#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q08379	intact:EBI-11522208	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	-	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:ylr445w(display_short)|psi-mi:EBI-11522208(display_long)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11522206|imex:IM-24995-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N|entrezgene/locuslink:2801(identity)	sgd:YLR445W(identity)	-	-	no-uniprot-update:	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2017/05/26	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	rogid:kUe7etYjGLH6i6KZ5N2LXUnjAf04932	intact-crc:DA91EB272E6D34D4|rigid:KkBN0sQ8Zc2sadqGnr4/J3iuD1A	false	sufficient binding region:383-1002	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
intact:EBI-11522220	uniprotkb:J3KPQ4	-	intact:EBI-11522225	psi-mi:lsb3(display_short)|psi-mi:EBI-11522220(display_long)	psi-mi:j3kpq4_human(display_long)|uniprotkb:hCG_39668(orf name)|uniprotkb:ARHGAP9(gene name)|psi-mi:ARHGAP9(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11522223|imex:IM-24995-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:YFR024C-A(identity)	interpro:IPR000198(RhoGAP)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035465|refseq:NP_001306779.1|go:"GO:0005096"(GTPase activator activity)|go:"GO:0007165"(signal transduction)|interpro:IPR036020|interpro:IPR036028|entrezgene/locuslink:64333(identity)	-	no-uniprot-update:	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:lsGJZWImagMoiiCZztCcxCn2LlU4932	rogid:H9MJrfHtg/AF6G6rqm+nDFz32lo9606	intact-crc:1F56C3D81CA01986|rigid:RtOoXkTmAlkeS6I+dTMX6DKn6hY	false	-	sufficient binding region:72-821	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
intact:EBI-11522238	uniprotkb:O14641	-	intact:EBI-740850|ensembl:ENSP00000005340|uniprotkb:Q53XM0|uniprotkb:D3DTN3	psi-mi:cyc2(display_short)|psi-mi:EBI-11522238(display_long)	psi-mi:dvl2_human(display_long)|uniprotkb:DSH homolog 2(gene name synonym)|uniprotkb:DVL2(gene name)|psi-mi:DVL2(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11522241|imex:IM-24995-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:YOR037W(identity)	refseq:NP_004413.1|ensembl:ENSG00000004975(gene)|ensembl:ENST00000005340(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005109"(frizzled binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0007507"(heart development)|go:"GO:0016235"(aggresome)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044340"(canonical Wnt signaling pathway involved in regulation of cell proliferation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0150012"(positive regulation of neuron projection arborization)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008341(Dishevelled-2 region)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:O14641|rcsb pdb:2REY|rcsb pdb:3CBX|rcsb pdb:3CBY|rcsb pdb:3CBZ|rcsb pdb:3CC0|rcsb pdb:4WIP|rcsb pdb:5LNP|rcsb pdb:5SUY|rcsb pdb:5SUZ|rcsb pdb:6IW3|rcsb pdb:6JCK|reactome:R-HSA-201681|reactome:R-HSA-201688|reactome:R-HSA-2028269|reactome:R-HSA-4086400|reactome:R-HSA-4608870|reactome:R-HSA-4641258|reactome:R-HSA-4641262|reactome:R-HSA-5099900|reactome:R-HSA-5368598|reactome:R-HSA-5663220|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9673324|ensembl:ENSP00000005340|dip:DIP-34433N|entrezgene/locuslink:1856(identity)	-	no-uniprot-update:	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:5RstlUmv8fpj9QSGrNaQaZc2OUU4932	rogid:2Vdc8oRnT4Mz/j+EXQXrL3AszOc9606	intact-crc:2E2CEC34B542BA56|rigid:VJEDE9PWZ37MtC3IhzljtXXrmE0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P14136	intact:EBI-11522220	intact:EBI-744302|uniprotkb:Q53H98|uniprotkb:Q5D055|uniprotkb:Q6ZQS3|uniprotkb:Q7Z5J6|uniprotkb:Q7Z5J7|uniprotkb:Q96KS4|uniprotkb:Q96P18|uniprotkb:Q9UFD0|uniprotkb:B2RD44|uniprotkb:D3DX59|intact:EBI-3909365|uniprotkb:E9PAX3|ensembl:ENSP00000466598|uniprotkb:A7REI1	-	psi-mi:gfap_human(display_long)|uniprotkb:GFAP(gene name)|psi-mi:GFAP(display_short)	psi-mi:lsb3(display_short)|psi-mi:EBI-11522220(display_long)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11522289|imex:IM-24995-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001124491.1|refseq:NP_001229305.1|refseq:NP_002046.1|ensembl:ENSG00000131095(gene)|ensembl:ENST00000588735(transcript)|go:"GO:0005178"(integrin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0009611"(response to wounding)|go:"GO:0010467"(gene expression)|go:"GO:0010625"(positive regulation of Schwann cell proliferation)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0014002"(astrocyte development)|go:"GO:0019900"(kinase binding)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0031102"(neuron projection regeneration)|go:"GO:0042802"(identical protein binding)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0044297"(cell body)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0051580"(regulation of neurotransmitter uptake)|go:"GO:0060020"(Bergmann glial cell differentiation)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0070779"(D-aspartate import across plasma membrane)|go:"GO:0097450"(astrocyte end-foot)|go:"GO:0098574"(cytoplasmic side of lysosomal membrane)|go:"GO:1904714"(regulation of chaperone-mediated autophagy)|interpro:IPR006821(Intermediate filament, DNA-binding region)|interpro:IPR018039|interpro:IPR027701|interpro:IPR039008|mint:P14136|rcsb pdb:6A9P|reactome:R-HSA-1251985|reactome:R-HSA-9613829|entrezgene/locuslink:2670(identity)	sgd:YFR024C-A(identity)	-	-	no-uniprot-update:	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Pz4JW0WjMjBYILTDSX9jUmMqWhg9606	rogid:lsGJZWImagMoiiCZztCcxCn2LlU4932	intact-crc:5721C3B153169E72|rigid:lWp7O9BNA3tICjiU1HeSWb4cvmo	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
intact:EBI-11522220	uniprotkb:O15156-2	-	intact:EBI-11522250|ensembl:ENSP00000406286	psi-mi:lsb3(display_short)|psi-mi:EBI-11522220(display_long)	psi-mi:o15156-2(display_long)|uniprotkb:ZBTB7B(gene name)|psi-mi:ZBTB7B(display_short)|uniprotkb:Krueppel-related zinc finger protein cKrox(gene name synonym)|uniprotkb:T-helper-inducing POZ/Krueppel-like factor(gene name synonym)|uniprotkb:ZBTB15(gene name synonym)|uniprotkb:ZFP67(gene name synonym)|uniprotkb:ZNF857B(gene name synonym)|uniprotkb:Zinc finger and BTB domain-containing protein 15(gene name synonym)|uniprotkb:Zinc finger protein 67 homolog(gene name synonym)|uniprotkb:Zinc finger protein 857B(gene name synonym)|uniprotkb:Zinc finger protein Th-POK(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11522254|imex:IM-24995-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:YFR024C-A(identity)	intact:EBI-740434(isoform-parent)|ensembl:ENSG00000160685(gene)|ensembl:ENST00000417934(transcript)|uniprotkb:O15156-2(isoform-parent)|entrezgene/locuslink:51043(identity)	-	no-uniprot-update:	isoform-comment:No experimental confirmation available.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:lsGJZWImagMoiiCZztCcxCn2LlU4932	rogid:41NEFYyprTXI+fOHVFh78TPKF289606	intact-crc:98EDA62E00B7AD65|rigid:8Xzv2aOPdULdtJOvuLu4NO8LkC8	false	-	sufficient binding region:35-573	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O43765	intact:EBI-11522265	intact:EBI-347996|ensembl:ENSP00000221566|ensembl:ENSP00000503397|ensembl:ENSP00000504495|uniprotkb:Q9BTZ9|intact:EBI-1045243|uniprotkb:Q6FIA9|uniprotkb:D6W610	-	psi-mi:sgta_human(display_long)|uniprotkb:SGTA(gene name)|psi-mi:SGTA(display_short)|uniprotkb:SGT(gene name synonym)|uniprotkb:Alpha-SGT(gene name synonym)|uniprotkb:Vpu-binding protein(gene name synonym)|uniprotkb:SGT1(gene name synonym)	psi-mi:pth2(display_short)|psi-mi:EBI-11522265(display_long)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11522268|imex:IM-24995-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:4CPG|rcsb pdb:4GOD|rcsb pdb:4GOE|rcsb pdb:4GOF|reactome:R-HSA-9609523|rcsb pdb:2VYI|ensembl:ENSG00000104969(gene)|ensembl:ENST00000221566(transcript)|ensembl:ENST00000676943(transcript)|ensembl:ENST00000677149(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072380"(TRC complex)|go:"GO:0098850"(extrinsic component of synaptic vesicle membrane)|go:"GO:1903070"(negative regulation of ER-associated ubiquitin-dependent protein catabolic process)|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)|go:"GO:1903646"(positive regulation of chaperone-mediated protein folding)|go:"GO:1904288"(BAT3 complex binding)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR032374|mint:O43765|refseq:XP_011526480.1|refseq:NP_003012.1|entrezgene/locuslink:6449(identity)	sgd:YBL057C(identity)	-	-	no-uniprot-update:	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:r/Cyj4UJk/cS8QdrbjhTZMPCigI9606	rogid:pRGxsdHHpne2ORtwUYJZXHw7qPA4932	intact-crc:8783F5D95BBAB2AA|rigid:Tr4HPuY4tbotOsKellP2JQdWRVc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
intact:EBI-11522279	uniprotkb:O95994	-	intact:EBI-712648|ensembl:ENSP00000391490	psi-mi:hsp150(display_short)|psi-mi:EBI-11522279(display_long)	psi-mi:agr2_human(display_long)|uniprotkb:Secreted cement gland protein XAG-2 homolog(gene name synonym)|uniprotkb:HPC8(gene name synonym)|uniprotkb:AG2(gene name synonym)|uniprotkb:UNQ515/PRO1030(orf name)|uniprotkb:AGR2(gene name)|psi-mi:AGR2(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11522277|imex:IM-24995-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:YJL159W(identity)	go:"GO:0005615"(extracellular space)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0042802"(identical protein binding)|go:"GO:0045742"(positive regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0048546"(digestive tract morphogenesis)|go:"GO:0048639"(positive regulation of developmental growth)|go:"GO:0060480"(lung goblet cell differentiation)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070254"(mucus secretion)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:1903896"(positive regulation of IRE1-mediated unfolded protein response)|go:"GO:1903899"(positive regulation of PERK-mediated unfolded protein response)|interpro:IPR036249|rcsb pdb:2LNS|rcsb pdb:2LNT|ensembl:ENSG00000106541(gene)|ensembl:ENST00000419304(transcript)|go:"GO:0002162"(dystroglycan binding)|go:"GO:0005154"(epidermal growth factor receptor binding)|refseq:NP_006399.1|refseq:XP_005249638.1|dip:DIP-48825N|entrezgene/locuslink:10551(identity)	-	no-uniprot-update:	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:6kfIxwLCGf2jj4GQK7oFLVnLfXU4932	rogid:E824a1MDXuGzk23ohjS7HAeEx5U9606	intact-crc:6122D88F307CD2FA|rigid:6Zb01R8bdSK9bglzfjUt4aN1QpQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
intact:EBI-11522208	uniprotkb:P43355	-	intact:EBI-740978|ensembl:ENSP00000349085|uniprotkb:O00346|uniprotkb:B2RC81	psi-mi:ylr445w(display_short)|psi-mi:EBI-11522208(display_long)	psi-mi:maga1_human(display_long)|uniprotkb:MAGE-1 antigen(gene name synonym)|uniprotkb:Antigen MZ2-E(gene name synonym)|uniprotkb:Cancer/testis antigen 1.1(gene name synonym)|uniprotkb:MAGEA1(gene name)|psi-mi:MAGEA1(display_short)|uniprotkb:MAGE1(gene name synonym)|uniprotkb:MAGE1A(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11522319|imex:IM-24995-10	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:YLR445W(identity)	refseq:NP_004979.3|ensembl:ENSG00000198681(gene)|ensembl:ENST00000356661(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|interpro:IPR002190(MAGE protein)|interpro:IPR021072|interpro:IPR030093|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|rcsb pdb:1W72|rcsb pdb:3BO8|dip:DIP-54794N|entrezgene/locuslink:4100(identity)	-	no-uniprot-update:	crc64:544EEB1F9F4E9D33	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:kUe7etYjGLH6i6KZ5N2LXUnjAf04932	rogid:6XW3mnTNM3yvOtXmiFbU8Uz3hjA9606	intact-crc:5B896B58B560189E|rigid:OyU+sBbEyvPELhKOadGOyFu9W4g	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
intact:EBI-11522220	uniprotkb:P14317	-	intact:EBI-750369|uniprotkb:B4DQ69|uniprotkb:Q53Y93|uniprotkb:Q6IBK9|uniprotkb:Q9UDK0|ensembl:ENSP00000320176	psi-mi:lsb3(display_short)|psi-mi:EBI-11522220(display_long)	psi-mi:hcls1_human(display_long)|uniprotkb:Hematopoietic cell-specific LYN substrate 1(gene name synonym)|uniprotkb:LckBP1(gene name synonym)|uniprotkb:p75(gene name synonym)|uniprotkb:HCLS1(gene name)|psi-mi:HCLS1(display_short)|uniprotkb:HS1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11522298|imex:IM-24995-8	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:YFR024C-A(identity)	ensembl:ENSP00000320176|ensembl:ENST00000495491|ensembl:ENSP00000418299|refseq:NP_001278970.1|refseq:NP_005326.2|ensembl:ENSG00000180353(gene)|ensembl:ENST00000314583(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009725"(response to hormone)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030427"(site of polarized growth)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030854"(positive regulation of granulocyte differentiation)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045651"(positive regulation of macrophage differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0051015"(actin filament binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:2000107"(negative regulation of leukocyte apoptotic process)|go:"GO:2000251"(positive regulation of actin cytoskeleton reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR003134(Hs1/Cortactin)|interpro:IPR028534|interpro:IPR036028|mint:P14317|entrezgene/locuslink:3059(identity)	-	no-uniprot-update:	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:lsGJZWImagMoiiCZztCcxCn2LlU4932	rogid:sViasWf8ZiLb/dmYn3VEr7t2L0Y9606	intact-crc:1F7BF763C5613E8B|rigid:pFBbhqbSkpRlbGtTdrie/j+YySs	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:A0A6A5PPQ8	uniprotkb:P40855	intact:EBI-11522307	intact:EBI-594747|uniprotkb:Q8NI97|intact:EBI-981972|uniprotkb:Q5QNY4|uniprotkb:D3DVE7|ensembl:ENSP00000357051	psi-mi:a0a6a5ppq8_yeasx(display_long)|uniprotkb:PACBIOSEQ_LOCUS4583(orf name)|uniprotkb:PACBIOSEQ_LOCUS4587(orf name)|uniprotkb:PACBIOSEQ_LOCUS4600(orf name)|uniprotkb:PACBIOSEQ_LOCUS4626(orf name)|uniprotkb:PACBIOSEQ_LOCUS4639(orf name)|uniprotkb:PACBIOSEQ_LOCUS4679(orf name)	psi-mi:pex19_human(display_long)|uniprotkb:PEX19(gene name)|psi-mi:PEX19(display_short)|uniprotkb:HK33(gene name synonym)|uniprotkb:PXF(gene name synonym)|uniprotkb:OK/SW-cl.22(orf name)|uniprotkb:Peroxin-19(gene name synonym)|uniprotkb:Peroxisomal farnesylated protein(gene name synonym)|uniprotkb:33 kDa housekeeping protein(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11522310|imex:IM-24995-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016021"(integral component of membrane)|uniprotkb:A0A250WEQ4(uniprot-removed-ac)|sgd:YMR122W-A(identity)	refseq:NP_001180573.1|refseq:NP_002848.1|dip:DIP-24172N|ensembl:ENSG00000162735(gene)|ensembl:ENST00000368072(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006625"(protein targeting to peroxisome)|go:"GO:0007031"(peroxisome organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016557"(peroxisome membrane biogenesis)|go:"GO:0016559"(peroxisome fission)|go:"GO:0031526"(brush border membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033328"(peroxisome membrane targeting sequence binding)|go:"GO:0036105"(peroxisome membrane class-1 targeting sequence binding)|go:"GO:0045046"(protein import into peroxisome membrane)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0072663"(establishment of protein localization to peroxisome)|go:"GO:0140597"(protein carrier chaperone)|go:"GO:1900131"(negative regulation of lipid binding)|interpro:IPR006708(Pex19 protein)|interpro:IPR038322|mint:P40855|rcsb pdb:2W85|rcsb pdb:2WL8|rcsb pdb:3AJB|rcsb pdb:3MK4|rcsb pdb:5LNF|reactome:R-HSA-1369062|reactome:R-HSA-9603798|entrezgene/locuslink:5824(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:f+RZksZwcG8Xqd6IVrksanQ54vE4932	rogid:yNnX2hPPJ7miGaz2Req0qFn0L189606	intact-crc:2227EED04BF8E4D9|rigid:ygWK9jcKDtOt4y7w3JAAtKGOTWE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
intact:EBI-11522371	uniprotkb:Q13422-7	-	intact:EBI-11522367|ensembl:ENSP00000352123|ensembl:ENSP00000413025	psi-mi:yjr003c(display_short)|psi-mi:EBI-11522371(display_long)	psi-mi:q13422-7(display_long)|uniprotkb:IKZF1(gene name)|psi-mi:IKZF1(display_short)|uniprotkb:IK1(gene name synonym)|uniprotkb:IKAROS(gene name synonym)|uniprotkb:Ikaros family zinc finger protein 1(gene name synonym)|uniprotkb:LYF1(gene name synonym)|uniprotkb:Lymphoid transcription factor LyF-1(gene name synonym)|uniprotkb:ZNFN1A1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11522374|imex:IM-24995-15	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:YJR003C(identity)	intact:EBI-745305(isoform-parent)|ensembl:ENSG00000185811(gene)|ensembl:ENST00000359197(transcript)|ensembl:ENST00000439701(transcript)|uniprotkb:Q13422-7(isoform-parent)|entrezgene/locuslink:10320(identity)	-	no-uniprot-update:	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:dYGrrP3JnrXO2rj4v/nTT64la6A4932	rogid:ou/ovXYoMneBNVp4pj38VxenfyY9606	intact-crc:E1C851372A7EC913|rigid:E0mitkr1eJGaEWkr0L13/d3MwQw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q13191	intact:EBI-11522220	intact:EBI-744027|uniprotkb:Q63Z43|uniprotkb:A8K9S7|uniprotkb:Q13192|uniprotkb:Q13193|uniprotkb:Q3LIC0|uniprotkb:Q8IVC5|uniprotkb:B7WNM4|intact:EBI-28969458|ensembl:ENSP00000377598|intact:EBI-8051403|intact:MINT-7907019	-	psi-mi:cblb_human(display_long)|uniprotkb:Signal transduction protein CBL-B(gene name synonym)|uniprotkb:SH3-binding protein CBL-B(gene name synonym)|uniprotkb:Casitas B-lineage lymphoma proto-oncogene b(gene name synonym)|uniprotkb:RING finger protein 56(gene name synonym)|uniprotkb:CBLB(gene name)|psi-mi:CBLB(display_short)|uniprotkb:RNF56(gene name synonym)|uniprotkb:Nbla00127(orf name)|uniprotkb:RING-type E3 ubiquitin transferase CBL-B(gene name synonym)	psi-mi:lsb3(display_short)|psi-mi:EBI-11522220(display_long)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11522358|imex:IM-24995-14	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_733762.2|refseq:NP_001308717.1|ensembl:ENSP00000377598|ensembl:ENST00000403724|ensembl:ENSP00000384816|ensembl:ENST00000405772|ensembl:ENSP00000384938|refseq:XP_011511559.1|ensembl:ENSG00000114423(gene)|ensembl:ENST00000394030(transcript)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0002669"(positive regulation of T cell anergy)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0007175"(negative regulation of epidermal growth factor-activated receptor activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0018193"(peptidyl-amino acid modification)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0005829"(cytosol)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042110"(T cell activation)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046642"(negative regulation of alpha-beta T cell proliferation)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050860"(negative regulation of T cell receptor signaling pathway)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:2000583"(regulation of platelet-derived growth factor receptor-alpha signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003153(Adaptor protein Cbl, N-terminal helical)|interpro:IPR011992(EF-Hand type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014742(Adaptor protein Cbl, SH2-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR017907|interpro:IPR024159|interpro:IPR024162|interpro:IPR036537|interpro:IPR036860|interpro:IPR039520|mint:Q13191|rcsb pdb:2AK5|rcsb pdb:2BZ8|rcsb pdb:2DO6|rcsb pdb:2J6F|rcsb pdb:2JNH|rcsb pdb:2LDR|rcsb pdb:2OOA|rcsb pdb:2OOB|rcsb pdb:3PFV|rcsb pdb:3VGO|rcsb pdb:3ZNI|reactome:R-HSA-983168|interpro:IPR014741(Adaptor protein Cbl, EF hand-like)|dip:DIP-33091N|entrezgene/locuslink:868(identity)	sgd:YFR024C-A(identity)	-	-	no-uniprot-update:	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:cJ5eLH0TMyM6OtmS1sM3rhsrsIk9606	rogid:lsGJZWImagMoiiCZztCcxCn2LlU4932	intact-crc:A6BECA969B5D2A40|rigid:b4mXxgUlwqy89aav6wvlaaGSutc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P43358	intact:EBI-11522208	intact:EBI-743122|ensembl:ENSP00000276344|ensembl:ENSP00000353379|ensembl:ENSP00000359360|ensembl:ENSP00000359365|ensembl:ENSP00000377497|ensembl:ENSP00000377498|ensembl:ENSP00000394149|ensembl:ENSP00000402186|ensembl:ENSP00000506838|ensembl:ENSP00000507023|uniprotkb:Q14798	-	psi-mi:maga4_human(display_long)|uniprotkb:MAGE-4 antigen(gene name synonym)|uniprotkb:MAGE-X2 antigen(gene name synonym)|uniprotkb:MAGE-41 antigen(gene name synonym)|uniprotkb:Cancer/testis antigen 1.4(gene name synonym)|uniprotkb:MAGEA4(gene name)|psi-mi:MAGEA4(display_short)|uniprotkb:MAGE4(gene name synonym)	psi-mi:ylr445w(display_short)|psi-mi:EBI-11522208(display_long)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11522328|imex:IM-24995-11	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000147381(gene)|ensembl:ENST00000276344(transcript)|ensembl:ENST00000360243(transcript)|ensembl:ENST00000370335(transcript)|ensembl:ENST00000370340(transcript)|ensembl:ENST00000393920(transcript)|ensembl:ENST00000393921(transcript)|ensembl:ENST00000430273(transcript)|ensembl:ENST00000457310(transcript)|ensembl:ENST00000682265(transcript)|ensembl:ENST00000684668(transcript)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045787"(positive regulation of cell cycle)|interpro:IPR002190(MAGE protein)|interpro:IPR021072|interpro:IPR030098|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|mint:P43358|rcsb pdb:1I4F|rcsb pdb:2WA0|rcsb pdb:6TRN|rcsb pdb:6TRO|refseq:NP_001011548.1|refseq:NP_001011549.1|refseq:NP_001011550.1|refseq:NP_002353.3|refseq:XP_005274735.1|refseq:XP_005274736.1|entrezgene/locuslink:4103(identity)	sgd:YLR445W(identity)	-	-	no-uniprot-update:	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:wF193QbpesCr14OlGMQD+BabWvs9606	rogid:kUe7etYjGLH6i6KZ5N2LXUnjAf04932	intact-crc:92AE3C1EABA8C8E3|rigid:MdsWg7Q3c+qYxXgxDIdBhk0IZso	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P51116	intact:EBI-11522220	intact:EBI-740459|uniprotkb:Q8WUM2|uniprotkb:Q86V09|uniprotkb:B2R9M2|uniprotkb:D3DTQ1|ensembl:ENSP00000250113	-	psi-mi:fxr2_human(display_long)|uniprotkb:FXR2(gene name)|psi-mi:FXR2(display_short)|uniprotkb:FMR1L2(gene name synonym)	psi-mi:lsb3(display_short)|psi-mi:EBI-11522220(display_long)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11522337|imex:IM-24995-12	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR004087(K Homology)|refseq:NP_004851.2|ensembl:ENSG00000129245(gene)|ensembl:ENST00000250113(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0044326"(dendritic spine neck)|go:"GO:0045182"(translation regulator activity)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0098793"(presynapse)|go:"GO:1902737"(dendritic filopodium)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|interpro:IPR004088(K Homology, type 1)|interpro:IPR008395(Agenet)|interpro:IPR022034|interpro:IPR032172|interpro:IPR036612|interpro:IPR040148|interpro:IPR040472|interpro:IPR041560|mint:P51116|rcsb pdb:3H8Z|entrezgene/locuslink:9513(identity)	sgd:YFR024C-A(identity)	-	-	no-uniprot-update:	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:NnYgyzD2NRGIO1ZHukr5qy44qRE9606	rogid:lsGJZWImagMoiiCZztCcxCn2LlU4932	intact-crc:29816DEE55C7E327|rigid:Ip2hgPhCGE2zPYgJQ9/bnSugGCk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
intact:EBI-11522346	uniprotkb:P63279	-	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	psi-mi:ctt1(display_short)|psi-mi:EBI-11522346(display_long)	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11522349|imex:IM-24995-13	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:YGR088W(identity)	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N|entrezgene/locuslink:7329(identity)	-	no-uniprot-update:	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:jNEGATUEb58kyyOUWh6Xi7tJTk04932	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	intact-crc:D3B9FADB8922722E|rigid:ZzCTm/J4wYAeXTuzTojCTEMWyUo	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
intact:EBI-11522371	uniprotkb:Q53EZ4	-	intact:EBI-747776|uniprotkb:Q32WF5|uniprotkb:Q3MV20|uniprotkb:Q5VY28|uniprotkb:Q6N034|ensembl:ENSP00000360540|uniprotkb:Q96H32|uniprotkb:Q9NVS7|uniprotkb:B2RDG8|intact:EBI-10173536|uniprotkb:D3DR37|intact:EBI-28973801	psi-mi:yjr003c(display_short)|psi-mi:EBI-11522371(display_long)	psi-mi:cep55_human(display_long)|uniprotkb:Up-regulated in colon cancer 6(gene name synonym)|uniprotkb:CEP55(gene name)|psi-mi:CEP55(display_short)|uniprotkb:URCC6(gene name synonym)|uniprotkb:C10orf3(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11522422|imex:IM-24995-20	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:YJR003C(identity)	refseq:NP_001120654.1|refseq:NP_060601.3|ensembl:ENSG00000138180(gene)|ensembl:ENST00000371485(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0014066"(regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0030496"(midbody)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042802"(identical protein binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0061952"(midbody abscission)|go:"GO:0090543"(Flemming body)|go:"GO:1904888"(cranial skeletal system development)|interpro:IPR022008|interpro:IPR038926|mint:Q53EZ4|rcsb pdb:3E1R|rcsb pdb:3WUT|rcsb pdb:3WUU|rcsb pdb:3WUV|go:"GO:0005814"(centriole)|ensembl:ENSP00000360540|dip:DIP-44581N|entrezgene/locuslink:55165(identity)	-	no-uniprot-update:	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:dYGrrP3JnrXO2rj4v/nTT64la6A4932	rogid:tuo36vVb8ZgPDR81YjZFNEg559w9606	intact-crc:358EB809A8F7C231|rigid:Ziq/qA2vX/etQxiTQCosKuYngCs	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
intact:EBI-11522403	uniprotkb:Q16637-3	-	intact:EBI-395447|ensembl:ENSP00000424926|ensembl:ENSP00000486152|ensembl:ENSP00000487015|ensembl:ENSP00000487029|intact:EBI-8628183|intact:MINT-95595	psi-mi:nhp2(display_short)|psi-mi:EBI-11522403(display_long)	psi-mi:q16637-3(display_long)|uniprotkb:Iso7-SMN(isoform synonym)|uniprotkb:SMN1(gene name)|psi-mi:SMN1(display_short)|uniprotkb:SMN2(gene name)|psi-mi:SMN2(display_short)|uniprotkb:SMN(gene name synonym)|uniprotkb:SMNT(gene name synonym)|uniprotkb:SMNC(gene name synonym)|uniprotkb:Component of gems 1(gene name synonym)|uniprotkb:Gemin-1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11522413|imex:IM-24995-19	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:YDL208W(identity)	intact:EBI-395421(smn_human)|ensembl:ENSG00000275349(gene)|ensembl:ENST00000506163(transcript)|ensembl:ENST00000626847(transcript)|ensembl:ENST00000628353(transcript)|ensembl:ENST00000628642(transcript)|ensembl:ENSG00000172062(gene)|ensembl:ENSG00000205571(gene)|ensembl:ENSG00000273772(gene)|uniprotkb:Q16637-3(isoform-parent)|entrezgene/locuslink:6607(identity)	-	no-uniprot-update:	isoform-comment:Thought to be a non-functional protein that lacks the capacity to oligomerize and thus cannot interact with Sm proteins. Primarily derived from SMN2 gene.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:FFduCSFjK3s7VNWPyW67FjyPE7Y4932	rogid:ICA63eidVxJ219M+YZJ20zNh+xU9606	intact-crc:6C19ECB9D8731588|rigid:F+LPh6d3R3r87DAdu/iZ1G3pXbA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q13829	intact:EBI-11522371	intact:EBI-2505861|uniprotkb:B7Z6M4|uniprotkb:Q5TZQ1|ensembl:ENSP00000226225	-	psi-mi:bacd2_human(display_long)|uniprotkb:BACURD2(gene name synonym)|uniprotkb:BTB/POZ domain-containing protein TNFAIP1(gene name synonym)|uniprotkb:Protein B12(gene name synonym)|uniprotkb:TNFAIP1(gene name)|psi-mi:TNFAIP1(display_short)|uniprotkb:EDP1(gene name synonym)|uniprotkb:Tumor necrosis factor, alpha-induced protein 1, endothelial(gene name synonym)	psi-mi:yjr003c(display_short)|psi-mi:EBI-11522371(display_long)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11522383|imex:IM-24995-16	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_066960.1|ensembl:ENSG00000109079(gene)|ensembl:ENST00000226225(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006955"(immune response)|go:"GO:0016477"(cell migration)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030332"(cyclin binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0043149"(stress fiber assembly)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0051260"(protein homooligomerization)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR003131(Potassium channel, voltage dependent, Kv,  tetramerisation)|interpro:IPR011333(BTB/POZ fold)|mint:Q13829|reactome:R-HSA-9696264|reactome:R-HSA-9696270|entrezgene/locuslink:7126(identity)	sgd:YJR003C(identity)	-	-	no-uniprot-update:	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:8vM9HnNmkirDbJRETV/TeE8pONY9606	rogid:dYGrrP3JnrXO2rj4v/nTT64la6A4932	intact-crc:71904085F4A119C7|rigid:9a3A/8NdlJMCCNvngc0qbz5NaMk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q15427	intact:EBI-11522220	intact:EBI-348469|ensembl:ENSP00000271628|intact:EBI-1047735|uniprotkb:Q5SZ63	-	psi-mi:sf3b4_human(display_long)|uniprotkb:SF3B4(gene name)|psi-mi:SF3B4(display_short)|uniprotkb:SAP49(gene name synonym)|uniprotkb:Spliceosome-associated protein 49(gene name synonym)|uniprotkb:Pre-mRNA-splicing factor SF3b 49 kDa subunit(gene name synonym)	psi-mi:lsb3(display_short)|psi-mi:EBI-11522220(display_long)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11522392|imex:IM-24995-17	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005841.1|ensembl:ENSG00000143368(gene)|ensembl:ENST00000271628(transcript)|rcsb pdb:6QX9|rcsb pdb:6Y53|rcsb pdb:6Y5Q|rcsb pdb:7ABG|rcsb pdb:7ABH|rcsb pdb:7ABI|rcsb pdb:7DVQ|reactome:R-HSA-72163|reactome:R-HSA-72165|rcsb pdb:6AHD|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:1990935"(splicing factor binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034158|go:"GO:0000375"(RNA splicing, via transesterification reactions)|interpro:IPR034159|interpro:IPR035979|mint:Q15427|rcsb pdb:1X5T|rcsb pdb:5GVQ|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|entrezgene/locuslink:10262(identity)	sgd:YFR024C-A(identity)	-	-	no-uniprot-update:	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Jgy6WmBFKkphpZLLte2GgsagUVI9606	rogid:lsGJZWImagMoiiCZztCcxCn2LlU4932	intact-crc:ED76FED24C964876|rigid:NuuZz3pXah3Iu9b4yqvrb3ZKfZE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
intact:EBI-11522403	uniprotkb:Q16637	-	intact:EBI-395421|uniprotkb:Q13119|uniprotkb:Q549U5|uniprotkb:Q96J51|ensembl:ENSP00000305857|uniprotkb:A8K0V4|ensembl:ENSP00000370083|ensembl:ENSP00000370117|ensembl:ENSP00000370119|ensembl:ENSP00000479920|ensembl:ENSP00000482966|ensembl:ENSP00000483515|ensembl:ENSP00000483819|ensembl:ENSP00000487206|ensembl:ENSP00000487421	psi-mi:nhp2(display_short)|psi-mi:EBI-11522403(display_long)	psi-mi:smn_human(display_long)|uniprotkb:SMN1(gene name)|psi-mi:SMN1(display_short)|uniprotkb:SMN(gene name synonym)|uniprotkb:SMNT(gene name synonym)|uniprotkb:SMN2(gene name)|psi-mi:SMN2(display_short)|uniprotkb:SMNC(gene name synonym)|uniprotkb:Component of gems 1(gene name synonym)|uniprotkb:Gemin-1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11522401|imex:IM-24995-18	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:YDL208W(identity)	refseq:NP_000335.1|refseq:NP_059107.1|refseq:NP_075012.1|refseq:NP_075013.1|refseq:NP_075014.1|refseq:NP_075015.1|ensembl:ENSG00000172062(gene)|ensembl:ENSG00000205571(gene)|ensembl:ENSG00000273772(gene)|ensembl:ENSG00000275349(gene)|ensembl:ENSG00000277773(gene)|ensembl:ENST00000351205(transcript)|ensembl:ENST00000380707(transcript)|ensembl:ENST00000380741(transcript)|ensembl:ENST00000380743(transcript)|ensembl:ENST00000614610(transcript)|ensembl:ENST00000618251(transcript)|ensembl:ENST00000618661(transcript)|ensembl:ENST00000622739(transcript)|ensembl:ENST00000627341(transcript)|ensembl:ENST00000629122(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0007399"(nervous system development)|go:"GO:0015030"(Cajal body)|go:"GO:0016604"(nuclear body)|go:"GO:0030018"(Z disc)|go:"GO:0030424"(axon)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043204"(perikaryon)|go:"GO:0097504"(Gemini of coiled bodies)|interpro:IPR002999(Tudor)|interpro:IPR010304(Survival motor neuron)|mint:Q16637|rcsb pdb:1G5V|rcsb pdb:1MHN|rcsb pdb:2LEH|rcsb pdb:4A4E|rcsb pdb:4A4G|rcsb pdb:4GLI|rcsb pdb:4QQ6|rcsb pdb:5XJL|go:"GO:0034719"(SMN-Sm protein complex)|rcsb pdb:5XJQ|rcsb pdb:5XJR|rcsb pdb:5XJS|rcsb pdb:5XJT|rcsb pdb:5XJU|reactome:R-HSA-191859|go:"GO:0032797"(SMN complex)|refseq:NP_001284644.1|ensembl:ENSP00000305857|ensembl:ENSP00000370083|ensembl:ENSP00000370117|ensembl:ENST00000380742|ensembl:ENSP00000370118|ensembl:ENSP00000370119|ensembl:ENST00000503079|ensembl:ENSP00000428128|ensembl:ENST00000506163|ensembl:ENSP00000424926|ensembl:ENST00000611442|ensembl:ENSP00000483768|ensembl:ENST00000614240|ensembl:ENSP00000479279|ensembl:ENSP00000479920|ensembl:ENST00000614773|ensembl:ENSP00000481427|ensembl:ENSP00000483515|ensembl:ENSP00000483819|ensembl:ENST00000622158|ensembl:ENSP00000480906|ensembl:ENSP00000482966|ensembl:ENST00000624634|ensembl:ENSP00000485595|ensembl:ENST00000626847|ensembl:ENSP00000486152|ensembl:ENSP00000487421|ensembl:ENST00000628353|ensembl:ENSP00000487029|ensembl:ENST00000628642|ensembl:ENSP00000487015|ensembl:ENSP00000487206|refseq:XP_016865275.1|dip:DIP-31309N|entrezgene/locuslink:6607(identity)	-	no-uniprot-update:	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:FFduCSFjK3s7VNWPyW67FjyPE7Y4932	rogid:QGivm7E8suciCWXO4l0zCUzCl2g9606	intact-crc:6FA0E04D73C6FEF8|rigid:kJnLGc37hChO//AWrVZFL3x7IuY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q5TD97	intact:EBI-11522444	intact:EBI-750641|uniprotkb:Q5TD98|uniprotkb:Q8WW21|uniprotkb:Q9NQU2|uniprotkb:B2RBD1|uniprotkb:E1P526|ensembl:ENSP00000326022|ensembl:ENSP00000396390|ensembl:ENSP00000442357	-	psi-mi:fhl5_human(display_long)|uniprotkb:Activator of cAMP-responsive element modulator in testis(gene name synonym)|uniprotkb:FHL5(gene name)|psi-mi:FHL5(display_short)|uniprotkb:ACT(gene name synonym)	psi-mi:sen15(display_short)|psi-mi:EBI-11522444(display_long)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11522447|imex:IM-24995-22	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164278.1|refseq:NP_065228.4|refseq:NP_001309395.1|refseq:NP_001309396.1|ensembl:ENSG00000112214(gene)|ensembl:ENST00000326771(transcript)|ensembl:ENST00000450218(transcript)|ensembl:ENST00000541107(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0030018"(Z disc)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR037987|interpro:IPR042947|mint:Q5TD97|rcsb pdb:1X68|entrezgene/locuslink:9457(identity)	sgd:YMR059W(identity)	-	-	no-uniprot-update:	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:AYHIHh+ibS4sNYAZY4ghojZOJOI9606	rogid:mmn7/rD7T68r+kJ8RV9USn4gnNI4932	intact-crc:09F4F468808D8A31|rigid:4Hg+guIIlsN0d0amItLmu80gYKc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
intact:EBI-11522371	uniprotkb:Q5JR59-3	-	intact:EBI-11522433|ensembl:ENSP00000370186	psi-mi:yjr003c(display_short)|psi-mi:EBI-11522371(display_long)	psi-mi:q5jr59-3(display_long)|uniprotkb:MTUS2(gene name)|psi-mi:MTUS2(display_short)|uniprotkb:CAZIP(gene name synonym)|uniprotkb:Cardiac zipper protein(gene name synonym)|uniprotkb:KIAA0774(gene name synonym)|uniprotkb:Microtubule plus-end tracking protein TIP150(gene name synonym)|uniprotkb:TIP150(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11522431|imex:IM-24995-21	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:YJR003C(identity)	ensembl:ENSG00000132938(gene)|ensembl:ENST00000380808(transcript)|intact:EBI-742948(isoform-parent)|uniprotkb:Q5JR59-3(isoform-parent)|entrezgene/locuslink:23281(identity)	-	no-uniprot-update:	isoform-comment:No experimental confirmation available.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:dYGrrP3JnrXO2rj4v/nTT64la6A4932	rogid:npId9tC7VoLN/jteoBiRbSYChPs9606	intact-crc:074505F07F88D5AA|rigid:/VcQ18j57lmRaJc5lZLRViDVBO8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8N6Y0	intact:EBI-11522208	intact:EBI-739895|uniprotkb:Q8NBX7|uniprotkb:Q96KH3|uniprotkb:Q9BYI8|uniprotkb:A8K7L6|uniprotkb:B2RCR9|ensembl:ENSP00000252597	-	psi-mi:usbp1_human(display_long)|uniprotkb:USHBP1(gene name)|psi-mi:USHBP1(display_short)|uniprotkb:MCC-2(gene name synonym)|uniprotkb:AIE-75-binding protein(gene name synonym)|uniprotkb:AIEBP(gene name synonym)|uniprotkb:MCC2(gene name synonym)|uniprotkb:Mutated in colon cancer protein 2(gene name synonym)	psi-mi:ylr445w(display_short)|psi-mi:EBI-11522208(display_long)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11522456|imex:IM-24995-23	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001284632.1|refseq:NP_114147.2|refseq:NP_001308346.1|ensembl:ENSG00000130307(gene)|ensembl:ENST00000252597(transcript)|go:"GO:0030165"(PDZ domain binding)|interpro:IPR019536|interpro:IPR040171|entrezgene/locuslink:83878(identity)	sgd:YLR445W(identity)	-	-	no-uniprot-update:	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:vY1qx73Ju/z7WDu6k1kd10ZDVRo9606	rogid:kUe7etYjGLH6i6KZ5N2LXUnjAf04932	intact-crc:E82F6382C9E08990|rigid:ZdV5IG7C1GfGBnajMMlqxT7pdQc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8NEH6	intact:EBI-11522371	intact:EBI-743811|uniprotkb:Q8IYT6|uniprotkb:Q9NUP4|ensembl:ENSP00000260453	-	psi-mi:mns1_human(display_long)|uniprotkb:MNS1(gene name)|psi-mi:MNS1(display_short)	psi-mi:yjr003c(display_short)|psi-mi:EBI-11522371(display_long)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11522465|imex:IM-24995-24	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060835.1|ensembl:ENSG00000138587(gene)|ensembl:ENST00000260453(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005882"(intermediate filament)|go:"GO:0005930"(axoneme)|go:"GO:0007288"(sperm axoneme assembly)|go:"GO:0031514"(motile cilium)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042802"(identical protein binding)|go:"GO:0044782"(cilium organization)|go:"GO:0045724"(positive regulation of cilium assembly)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070986"(left/right axis specification)|interpro:IPR026504|interpro:IPR043597|mint:Q8NEH6|entrezgene/locuslink:55329(identity)	sgd:YJR003C(identity)	-	-	no-uniprot-update:	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:MRimzaWPUjIEXfbT3YufZtjt7Fk9606	rogid:dYGrrP3JnrXO2rj4v/nTT64la6A4932	intact-crc:0531A310F1211A2D|rigid:+zu8ArXu8e08GzieRA9lcwUAg1U	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
intact:EBI-11522371	uniprotkb:Q8NHQ1	-	intact:EBI-739624|ensembl:ENSP00000264982|ensembl:ENSP00000419231|uniprotkb:Q96B31|uniprotkb:Q9H2C3|uniprotkb:Q9H2Z1|uniprotkb:Q9H940|uniprotkb:D3DNE9|uniprotkb:B7Z5I8|uniprotkb:B7Z7E8|uniprotkb:F5GZX8	psi-mi:yjr003c(display_short)|psi-mi:EBI-11522371(display_long)	psi-mi:cep70_human(display_long)|uniprotkb:CEP70(gene name)|psi-mi:CEP70(display_short)|uniprotkb:BITE(gene name synonym)|uniprotkb:p10-binding protein(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11522474|imex:IM-24995-25	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:YJR003C(identity)	ensembl:ENSG00000114107(gene)|ensembl:ENST00000264982(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|interpro:IPR019734|interpro:IPR037692|mint:Q8NHQ1|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|ensembl:ENST00000484888(transcript)|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_077817.2|refseq:XP_016862764.1|refseq:NP_001275893.1|refseq:NP_001275894.1|refseq:NP_001275895.1|refseq:NP_001275896.1|refseq:NP_001307527.1|refseq:NP_001307529.1|entrezgene/locuslink:80321(identity)	-	no-uniprot-update:	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:dYGrrP3JnrXO2rj4v/nTT64la6A4932	rogid:S4yveQWcvdVtAUX65gqrJ5Dv0Mc9606	intact-crc:550C476B038D4DAC|rigid:jjEF/VSJJhKBsAhjrSDzZiMDUfo	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
intact:EBI-11522371	uniprotkb:Q96IK5	-	intact:EBI-2548508|ensembl:ENSP00000282570|uniprotkb:Q9H826|uniprotkb:Q9H8V7|uniprotkb:Q9H927	psi-mi:yjr003c(display_short)|psi-mi:EBI-11522371(display_long)	psi-mi:gmcl1_human(display_long)|uniprotkb:GMCL1(gene name)|psi-mi:GMCL1(display_short)|uniprotkb:GCL(gene name synonym)|uniprotkb:BTBD13(gene name synonym)|uniprotkb:SPATA29(gene name synonym)|uniprotkb:Spermatogenesis-associated protein 29(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11522530|imex:IM-24995-30	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:YJR003C(identity)	ensembl:ENSG00000087338(gene)|ensembl:ENST00000282570(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0007281"(germ cell development)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016363"(nuclear matrix)|go:"GO:0042802"(identical protein binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR043380|refseq:NP_848526.1|entrezgene/locuslink:64395(identity)	-	no-uniprot-update:	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:dYGrrP3JnrXO2rj4v/nTT64la6A4932	rogid:ED8yqySVu7BWxpw3DUSNBZSQWrk9606	intact-crc:1E66577CD0B38D5E|rigid:dbccop0gcphLz75QVz1aGzwaVvg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96BA8	intact:EBI-11522518	intact:EBI-6942903|ensembl:ENSP00000481956|intact:MINT-268046|intact:MINT-8162577|uniprotkb:Q8N2D5|uniprotkb:Q96CP0	-	psi-mi:cr3l1_human(display_long)|uniprotkb:CREB3L1(gene name)|psi-mi:CREB3L1(display_short)|uniprotkb:OASIS(gene name synonym)|uniprotkb:PSEC0238(orf name)|uniprotkb:Old astrocyte specifically-induced substance(gene name synonym)	psi-mi:ost2(display_short)|psi-mi:EBI-11522518(display_long)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11522521|imex:IM-24995-29	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157613(gene)|ensembl:ENST00000621158(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0070278"(extracellular matrix constituent secretion)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029805|mint:Q96BA8|reactome:R-HSA-8874211|refseq:NP_443086.1|entrezgene/locuslink:90993(identity)	sgd:YOR103C(identity)	-	comment:mint|function:"Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE"	no-uniprot-update:	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:sMWUFmBeBBCO+T0Y2CuB/un1lBg9606	rogid:3gHEG/j4fiaHHY/qWGorqbRMBsg4932	intact-crc:42B26881843A5EAA|rigid:XEPVU11Ksmf99eDRO+Gztb1+AeY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q92841	intact:EBI-11522220	intact:EBI-746012|uniprotkb:Q69YT1|uniprotkb:Q6ICD6|uniprotkb:H3BLZ8|uniprotkb:B1AHM0|ensembl:ENSP00000385536	-	psi-mi:ddx17_human(display_long)|uniprotkb:DEAD box protein 17(gene name synonym)|uniprotkb:RNA-dependent helicase p72(gene name synonym)|uniprotkb:DEAD box protein p72(gene name synonym)|uniprotkb:DDX17(gene name)|psi-mi:DDX17(display_short)|uniprotkb:DEAD box protein p82(gene name synonym)	psi-mi:lsb3(display_short)|psi-mi:EBI-11522220(display_long)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11522483|imex:IM-24995-26	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006377.2|ensembl:ENSG00000100201(gene)|ensembl:ENST00000403230(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006364"(rRNA processing)|go:"GO:0006396"(RNA processing)|go:"GO:0008186"(ATP-dependent activity, acting on RNA)|go:"GO:0010586"(miRNA metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0045445"(myoblast differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051607"(defense response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2001014"(regulation of skeletal muscle cell differentiation)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:Q92841|rcsb pdb:6UV0|rcsb pdb:6UV1|rcsb pdb:6UV2|rcsb pdb:6UV3|rcsb pdb:6UV4|reactome:R-HSA-3899300|dip:DIP-29843N|entrezgene/locuslink:10521(identity)	sgd:YFR024C-A(identity)	-	-	no-uniprot-update:	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:3UhUuhRSZg/zlM7UPDKYCqNmUho9606	rogid:lsGJZWImagMoiiCZztCcxCn2LlU4932	intact-crc:BBE73DBBCC9FBB1B|rigid:v6GkDh8mDkD5LIPm/bIWOwh+zZ0	false	sufficient binding region:80-729	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:A0A6L1C4M5	uniprotkb:Q969F0	intact:EBI-11522494	intact:EBI-743099|ensembl:ENSP00000359375	psi-mi:a0a6l1c4m5_yeasx(display_long)|uniprotkb:PACBIOSEQ_LOCUS6219(orf name)|uniprotkb:PACBIOSEQ_LOCUS6225(orf name)|uniprotkb:PACBIOSEQ_LOCUS6235(orf name)|uniprotkb:PACBIOSEQ_LOCUS6264(orf name)|uniprotkb:PACBIOSEQ_LOCUS6286(orf name)|uniprotkb:PACBIOSEQ_LOCUS6327(orf name)|uniprotkb:SCNYR20_0005038000(orf name)|uniprotkb:SCP684_0005037600(orf name)	psi-mi:fate1_human(display_long)|uniprotkb:Tumor antigen BJ-HCC-2(gene name synonym)|uniprotkb:Cancer/testis antigen 43(gene name synonym)|uniprotkb:FATE1(gene name)|psi-mi:FATE1(display_short)|uniprotkb:FATE(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11522497|imex:IM-24995-27	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016021"(integral component of membrane)|uniprotkb:A0A250WEI1(uniprot-removed-ac)|interpro:IPR019334|sgd:YPR153W(identity)	refseq:NP_149076.1|ensembl:ENSG00000147378(gene)|ensembl:ENST00000370350(transcript)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|go:"GO:0051562"(negative regulation of mitochondrial calcium ion concentration)|interpro:IPR039153|interpro:IPR039433|mint:Q969F0|entrezgene/locuslink:89885(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:SRq+kqkRupgoOO2oywFAv0D2VGc4932	rogid:Nm1N6lO92MHr5rIKC007oouF5RE9606	intact-crc:DB6FB2B4BA80426E|rigid:q8MR7lCVVaclXUxjJkQXOdptm2w	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q969F0	intact:EBI-11522506	intact:EBI-743099|ensembl:ENSP00000359375	-	psi-mi:fate1_human(display_long)|uniprotkb:Tumor antigen BJ-HCC-2(gene name synonym)|uniprotkb:Cancer/testis antigen 43(gene name synonym)|uniprotkb:FATE1(gene name)|psi-mi:FATE1(display_short)|uniprotkb:FATE(gene name synonym)	psi-mi:mps3(display_short)|psi-mi:EBI-11522506(display_long)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11522509|imex:IM-24995-28	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_149076.1|ensembl:ENSG00000147378(gene)|ensembl:ENST00000370350(transcript)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|go:"GO:0051562"(negative regulation of mitochondrial calcium ion concentration)|interpro:IPR039153|interpro:IPR039433|mint:Q969F0|entrezgene/locuslink:89885(identity)	sgd:YJL019W(identity)	-	-	no-uniprot-update:	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Nm1N6lO92MHr5rIKC007oouF5RE9606	rogid:L0dsobyr9SpxA4nDPBr9V2OBaqU4932	intact-crc:64D27A500A0598CF|rigid:2wk6m3/qprPOZIJ4MLIY5UEXyU0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
intact:EBI-11522208	uniprotkb:Q9NPJ6	-	intact:EBI-394607|uniprotkb:Q9BS95|uniprotkb:Q9NYR5|uniprotkb:Q53GB4|uniprotkb:Q53H68|uniprotkb:Q5T912|uniprotkb:Q6FHC4|uniprotkb:Q6IA79|uniprotkb:B4DX67|ensembl:ENSP00000258648	psi-mi:ylr445w(display_short)|psi-mi:EBI-11522208(display_long)	psi-mi:med4_human(display_long)|uniprotkb:HSPC126(orf name)|uniprotkb:DRIP36(gene name synonym)|uniprotkb:MED4(gene name)|psi-mi:MED4(display_short)|uniprotkb:ARC36(gene name synonym)|uniprotkb:Mediator complex subunit 4(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex 36 kDa component(gene name synonym)|uniprotkb:Activator-recruited cofactor 36 kDa component(gene name synonym)|uniprotkb:TRAP/SMCC/PC2 subunit p36 subunit(gene name synonym)|uniprotkb:VDRIP(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11522585|imex:IM-24995-35	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:YLR445W(identity)	refseq:NP_001257558.1|refseq:NP_054885.1|ensembl:ENSG00000136146(gene)|ensembl:ENST00000258648(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0070847"(core mediator complex)|interpro:IPR019258|mint:Q9NPJ6|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|entrezgene/locuslink:29079(identity)	-	no-uniprot-update:	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:kUe7etYjGLH6i6KZ5N2LXUnjAf04932	rogid:Bept2Oec50gruA9e4pf+eEUiANM9606	intact-crc:563F1FFEACFF5DBD|rigid:5GC7wSGOu6bpZglvGPIeDsMqEms	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9HD26-2	intact:EBI-11522575	intact:EBI-11102276|ensembl:ENSP00000052569	-	psi-mi:q9hd26-2(display_long)|uniprotkb:GOPC(gene name)|psi-mi:GOPC(display_short)|uniprotkb:CAL(gene name synonym)|uniprotkb:CFTR-associated ligand(gene name synonym)|uniprotkb:FIG(gene name synonym)|uniprotkb:Fused in glioblastoma(gene name synonym)|uniprotkb:PDZ protein interacting specifically with TC10(gene name synonym)	psi-mi:mrpl15(display_short)|psi-mi:EBI-11522575(display_long)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11522573|imex:IM-24995-34	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000047932(gene)|ensembl:ENST00000052569(transcript)|intact:EBI-349832(isoform-parent)|uniprotkb:Q9HD26-2(isoform-parent)|entrezgene/locuslink:57120(identity)	sgd:YLR312W-A(identity)	-	-	no-uniprot-update:	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:QoEGY54FfmwTrpGVMQN9ASGPgVI9606	rogid:ZU12R+PdYknw8Q1ARUw5V55WN/84932	intact-crc:84BDF98A4F82F133|rigid:vQuqXIXBBj18kH4Ysh8GtSN2BtU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
intact:EBI-11522371	uniprotkb:Q96MT8-3	-	intact:EBI-11522539|ensembl:ENSP00000507703|ensembl:ENSP00000328382|ensembl:ENSP00000506728|ensembl:ENSP00000506791|ensembl:ENSP00000506828|ensembl:ENSP00000507228	psi-mi:yjr003c(display_short)|psi-mi:EBI-11522371(display_long)	psi-mi:q96mt8-3(display_long)|uniprotkb:CEP63(gene name)|psi-mi:CEP63(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11522543|imex:IM-24995-31	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:YJR003C(identity)	intact:EBI-741977(isoform-parent)|ensembl:ENST00000332047(transcript)|ensembl:ENST00000682042(transcript)|ensembl:ENST00000682800(transcript)|ensembl:ENST00000682858(transcript)|ensembl:ENST00000683177(transcript)|ensembl:ENST00000683861(transcript)|ensembl:ENSG00000182923(gene)|uniprotkb:Q96MT8-3(isoform-parent)|entrezgene/locuslink:80254(identity)	-	no-uniprot-update:	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:dYGrrP3JnrXO2rj4v/nTT64la6A4932	rogid:U0uvVcOCzA8Qp2cCB0ilixgd4Yc9606	intact-crc:EAD41442552DC5D7|rigid:vrpSQQZOtDJzpIaBlSp7W6As+vI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9C005	intact:EBI-11522552	intact:EBI-744973|uniprotkb:D6W578|ensembl:ENSP00000295066|ensembl:ENSP00000345837	-	psi-mi:dpy30_human(display_long)|uniprotkb:DPY30(gene name)|psi-mi:DPY30(display_short)|uniprotkb:Dpy-30-like protein(gene name synonym)	psi-mi:urh1(display_short)|psi-mi:EBI-11522552(display_long)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11522555|imex:IM-24995-32	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_115963.1|ensembl:ENSG00000162961(gene)|ensembl:ENST00000295066(transcript)|ensembl:ENST00000342166(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006348"|go:"GO:0016197"(endosomal transport)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|interpro:IPR007858(Dpy-30)|interpro:IPR037856|mint:Q9C005|rcsb pdb:3G36|rcsb pdb:4RIQ|rcsb pdb:4RT4|rcsb pdb:4RTA|rcsb pdb:6E2H|rcsb pdb:6PWV|reactome:R-HSA-3214841|reactome:R-HSA-8936459|refseq:NP_001308138.1|dip:DIP-34476N|entrezgene/locuslink:84661(identity)	sgd:YDR400W(identity)	-	-	no-uniprot-update:	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:yC9NJhTfEIT+YyfWRSJLGbRsQkc9606	rogid:uuys9fg/B71sAw+Tb2BvegAXdp84932	intact-crc:F1AF318F4FA80EDC|rigid:EL2T1hfc1Qz1xHaMPIuYHKHh9+c	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9H9H4	intact:EBI-11522220	intact:EBI-4400866|intact:EBI-28975719|ensembl:ENSP00000267202	-	psi-mi:vp37b_human(display_long)|uniprotkb:VPS37B(gene name)|psi-mi:VPS37B(display_short)|uniprotkb:ESCRT-I complex subunit VPS37B(gene name synonym)	psi-mi:lsb3(display_short)|psi-mi:EBI-11522220(display_long)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11522564|imex:IM-24995-33	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000267202|refseq:NP_078943.1|ensembl:ENSG00000139722(gene)|ensembl:ENST00000267202(transcript)|go:"GO:0000813"(ESCRT I complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0010008"(endosome membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0030496"(midbody)|go:"GO:0031902"(late endosome membrane)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1902188"(obsolete positive regulation of viral release from host cell)|go:"GO:1903774"(positive regulation of viral budding via host ESCRT complex)|interpro:IPR009851(Modifier of rudimentary, Modr)|interpro:IPR029012|interpro:IPR037202|mint:Q9H9H4|rcsb pdb:6VME|reactome:R-HSA-162588|reactome:R-HSA-174490|reactome:R-HSA-917729|reactome:R-HSA-9610379|reactome:R-HSA-9615710|entrezgene/locuslink:79720(identity)	sgd:YFR024C-A(identity)	-	-	no-uniprot-update:	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:dj398+zsegXf+gk9OiSeZAVlmqk9606	rogid:lsGJZWImagMoiiCZztCcxCn2LlU4932	intact-crc:0C3A36FA0EDCF6B6|rigid:UNiURDIqj4ktekX/LN3iVCNQy6o	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O13539	uniprotkb:Q7Z6G3-2	intact:EBI-30898|uniprotkb:D3DLB6|ensemblfungi:YHR167W	intact:EBI-10172876|ensembl:ENSP00000457354|intact:EBI-14062040	psi-mi:thp2_yeast(display_long)|uniprotkb:THP2(gene name)|psi-mi:THP2(display_short)|uniprotkb:YHR167W(locus name)	psi-mi:q7z6g3-2(display_long)|uniprotkb:EFCBP2(gene name synonym)|uniprotkb:Neuronal calcium-binding protein 2(gene name synonym)|uniprotkb:Synaptotagmin-interacting protein 2(gene name synonym)|uniprotkb:NECAB2(gene name)|psi-mi:NECAB2(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11522638|imex:IM-24995-40	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012037.1|sgd:S000001210|dip:DIP-4246N|mint:O13539|ensemblfungi:YHR167W(gene)|ensemblfungi:YHR167W_mRNA(transcript)|go:"GO:0000445"(THO complex part of transcription export complex)|go:"GO:0000446"(nucleoplasmic THO complex)|go:"GO:0000723"(telomere maintenance)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0006310"(DNA recombination)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0034063"(stress granule assembly)|interpro:IPR018557|rcsb pdb:7APX|rcsb pdb:7LUV|sgd:YHR167W(identity)	ensembl:ENSG00000103154(gene)|ensembl:ENST00000565691(transcript)|uniprotkb:Q7Z6G3-2(isoform-parent)|intact:EBI-950070(isoform-parent)|entrezgene/locuslink:54550(identity)	-	crc64:16EFA6F464507C57	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:SaTSL6jLwX1hTVCqvU8ZNR96r8U559292	rogid:4S7oIx6h+mKzV3EPxqcfMNqaNko9606	intact-crc:E4DA667832469F2A|rigid:V2uDZVRRDFQLR0A82FXu/kkIes8	false	-	sufficient binding region:65-303	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UMX0	intact:EBI-11522626	intact:EBI-741480|uniprotkb:Q8IXS9|uniprotkb:Q8N2Q3|uniprotkb:Q9H0T8|uniprotkb:Q9H3R4|uniprotkb:Q9HAZ5|intact:EBI-28967608|ensembl:ENSP00000365576|uniprotkb:Q5T6J5|uniprotkb:Q5T6J9|uniprotkb:A0A024R284	-	psi-mi:ubql1_human(display_long)|uniprotkb:Protein linking IAP with cytoskeleton 1(gene name synonym)|uniprotkb:UBQLN1(gene name)|psi-mi:UBQLN1(display_short)|uniprotkb:DA41(gene name synonym)|uniprotkb:PLIC1(gene name synonym)	psi-mi:a0a6a5q521_yeasx(display_short)|psi-mi:EBI-11522626(display_long)|uniprotkb:PACBIOSEQ_LOCUS284(orf name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11522629|imex:IM-24995-39	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000257468|ensembl:ENSP00000257468|ensembl:ENSP00000365576|ensembl:ENSG00000135018(gene)|ensembl:ENST00000376395(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000502"(proteasome complex)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016235"(aggresome)|go:"GO:0016236"(macroautophagy)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0019900"(kinase binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035973"(aggrephagy)|go:"GO:0042802"(identical protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0097352"(autophagosome maturation)|go:"GO:1901340"(negative regulation of store-operated calcium channel activity)|go:"GO:1902175"(regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)|interpro:IPR000626(Ubiquitin)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR028430|interpro:IPR029071|mint:Q9UMX0|rcsb pdb:2JY5|rcsb pdb:2JY6|rcsb pdb:2KLC|reactome:R-HSA-8856825|refseq:NP_038466.2|refseq:NP_444295.1|dip:DIP-41629N|entrezgene/locuslink:29979(identity)	uniprotkb:A0A6A5Q521(uniprot-removed-ac)|sgd:YBR067C(identity)	-	-	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:nCFfZbGCTvRYaXhQ4R99XblslvM9606	rogid:FaEZGfVcEXllbT1sM1VpEOeuSZ44932	intact-crc:427BEC5901F63944|rigid:Tg01hQ8vVfdjzmV3F2fkNjQw2B4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
intact:EBI-11522552	uniprotkb:Q9UGJ1-2	-	intact:EBI-10964469|ensembl:ENSP00000456648	psi-mi:urh1(display_short)|psi-mi:EBI-11522552(display_long)	psi-mi:q9ugj1-2(display_long)|uniprotkb:TUBGCP4(gene name)|psi-mi:TUBGCP4(display_short)|uniprotkb:76P(gene name synonym)|uniprotkb:GCP4(gene name synonym)|uniprotkb:Gamma-ring complex protein 76 kDa(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11522594|imex:IM-24995-36	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:YDR400W(identity)	intact:EBI-1052544(isoform-parent)|ensembl:ENSG00000137822(gene)|ensembl:ENST00000564079(transcript)|uniprotkb:Q9UGJ1-2(isoform-parent)|entrezgene/locuslink:27229(identity)	-	no-uniprot-update:	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:uuys9fg/B71sAw+Tb2BvegAXdp84932	rogid:+lfeIRS3N2OU1+y84kUyKY7ePNA9606	intact-crc:E45EA91049020C2B|rigid:00J1gknyAajcVLBEJSsfaooFtGE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UJX2	intact:EBI-11522371	intact:EBI-396137|uniprotkb:O75433|uniprotkb:Q9BS73|uniprotkb:B4E3A2|uniprotkb:B7WP05|uniprotkb:Q53FN2|uniprotkb:A8K6E5|uniprotkb:D3DQB7|ensembl:ENSP00000378350	-	psi-mi:cdc23_human(display_long)|uniprotkb:CDC23(gene name)|psi-mi:CDC23(display_short)|uniprotkb:ANAPC8(gene name synonym)|uniprotkb:Anaphase-promoting complex subunit 8(gene name synonym)|uniprotkb:Cyclosome subunit 8(gene name synonym)	psi-mi:yjr003c(display_short)|psi-mi:EBI-11522371(display_long)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11522603|imex:IM-24995-37	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004652.2|dip:DIP-32959N|ensembl:ENSG00000094880(gene)|ensembl:ENST00000394886(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0007091"(metaphase/anaphase transition of mitotic cell cycle)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030071"(regulation of mitotic metaphase/anaphase transition)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0051301"(cell division)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR007192(Cdc23)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|mint:Q9UJX2|rcsb pdb:4UI9|rcsb pdb:5A31|rcsb pdb:5G04|rcsb pdb:5G05|rcsb pdb:5KHR|rcsb pdb:5KHU|rcsb pdb:5L9T|rcsb pdb:5L9U|rcsb pdb:5LCW|rcsb pdb:6Q6G|rcsb pdb:6Q6H|rcsb pdb:6TLJ|rcsb pdb:6TM5|rcsb pdb:6TNT|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-9687136|reactome:R-HSA-983168|entrezgene/locuslink:8697(identity)	sgd:YJR003C(identity)	-	-	no-uniprot-update:	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:uTZL2UHzZHLoKnio/1LcuSzZpW09606	rogid:dYGrrP3JnrXO2rj4v/nTT64la6A4932	intact-crc:D262CE239FF9A445|rigid:PDeq10RYhZ+fN+OuxIR+rI3fZWw	false	sufficient binding region:7-597	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:A0A6A5PVQ3	uniprotkb:Q9UMX0	intact:EBI-11522614	intact:EBI-741480|uniprotkb:Q8IXS9|uniprotkb:Q8N2Q3|uniprotkb:Q9H0T8|uniprotkb:Q9H3R4|uniprotkb:Q9HAZ5|intact:EBI-28967608|ensembl:ENSP00000365576|uniprotkb:Q5T6J5|uniprotkb:Q5T6J9|uniprotkb:A0A024R284	psi-mi:a0a6a5pvq3_yeasx(display_long)|uniprotkb:PACBIOSEQ_LOCUS3560(orf name)|uniprotkb:PACBIOSEQ_LOCUS3564(orf name)|uniprotkb:PACBIOSEQ_LOCUS3592(orf name)|uniprotkb:PACBIOSEQ_LOCUS3594(orf name)|uniprotkb:PACBIOSEQ_LOCUS3635(orf name)|uniprotkb:SCNYR20_0010010900(orf name)|uniprotkb:SCP684_0010010800(orf name)	psi-mi:ubql1_human(display_long)|uniprotkb:Protein linking IAP with cytoskeleton 1(gene name synonym)|uniprotkb:UBQLN1(gene name)|psi-mi:UBQLN1(display_short)|uniprotkb:DA41(gene name synonym)|uniprotkb:PLIC1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11522617|imex:IM-24995-38	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR000420(Yeast PIR protein repeat)|go:"GO:0005199"(structural constituent of cell wall)|go:"GO:0005618"(cell wall)|uniprotkb:A0A250WIX2(uniprot-removed-ac)|sgd:YKL096W-A(identity)	ensembl:ENST00000257468|ensembl:ENSP00000257468|ensembl:ENSP00000365576|ensembl:ENSG00000135018(gene)|ensembl:ENST00000376395(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000502"(proteasome complex)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016235"(aggresome)|go:"GO:0016236"(macroautophagy)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0019900"(kinase binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035973"(aggrephagy)|go:"GO:0042802"(identical protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0097352"(autophagosome maturation)|go:"GO:1901340"(negative regulation of store-operated calcium channel activity)|go:"GO:1902175"(regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)|interpro:IPR000626(Ubiquitin)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR028430|interpro:IPR029071|mint:Q9UMX0|rcsb pdb:2JY5|rcsb pdb:2JY6|rcsb pdb:2KLC|reactome:R-HSA-8856825|refseq:NP_038466.2|refseq:NP_444295.1|dip:DIP-41629N|entrezgene/locuslink:29979(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:I1pf6N/8dUODvb5jhcXC902uuew4932	rogid:nCFfZbGCTvRYaXhQ4R99XblslvM9606	intact-crc:A03364AFE6026310|rigid:+8QzAI8pX+olAfWRefZI12z170I	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O14468	uniprotkb:Q96HT8	intact:EBI-2343965|uniprotkb:D6W304|ensemblfungi:YOR304C-A	intact:EBI-748896|uniprotkb:Q6NXT8|uniprotkb:Q9P0J5|uniprotkb:B2R6R0|ensembl:ENSP00000318154	psi-mi:yo304_yeast(display_long)|uniprotkb:YOR304C-A(locus name)	psi-mi:mr1l1_human(display_long)|uniprotkb:PP784(orf name)|uniprotkb:MRFAP1L1(gene name)|psi-mi:MRFAP1L1(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11522709|imex:IM-24995-47	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005830|refseq:NP_014949.3|mint:O14468|ensemblfungi:YOR304C-A(gene)|ensemblfungi:YOR304C-A_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005933"(cellular bud)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0043332"(mating projection tip)|go:"GO:0051017"(actin filament bundle assembly)|sgd:YOR304C-A(identity)	refseq:NP_982287.1|refseq:XP_005247989.1|ensembl:ENSG00000178988(gene)|ensembl:ENST00000320848(transcript)|go:"GO:0042802"(identical protein binding)|interpro:IPR029254|mint:Q96HT8|dip:DIP-29019N|entrezgene/locuslink:114932(identity)	-	-	caution:This sequence has been withdrawn from Uniprot.|crc64:6C914B0B4BEECAE5	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:+5KU/P9FeqlhSbGhpYJ1V6DqQNg559292	rogid:hb4enqSS7DeieOByDoLDkXkSlIk9606	intact-crc:CC277D0038240248|rigid:vkfqnxFf5tR9GxUo1dAyIRUfIB0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O14468	uniprotkb:Q8TC20-4	intact:EBI-2343965|uniprotkb:D6W304|ensemblfungi:YOR304C-A	intact:EBI-11522698|ensembl:ENSP00000390644	psi-mi:yo304_yeast(display_long)|uniprotkb:YOR304C-A(locus name)	psi-mi:q8tc20-4(display_long)|uniprotkb:CTAG3(gene name synonym)|uniprotkb:Cancer/testis antigen 3(gene name synonym)|uniprotkb:CAGE1(gene name)|psi-mi:CAGE1(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11522696|imex:IM-24995-46	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005830|refseq:NP_014949.3|mint:O14468|ensemblfungi:YOR304C-A(gene)|ensemblfungi:YOR304C-A_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005933"(cellular bud)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0043332"(mating projection tip)|go:"GO:0051017"(actin filament bundle assembly)|sgd:YOR304C-A(identity)	intact:EBI-10196469(isoform-parent)|ensembl:ENSG00000164304(gene)|ensembl:ENST00000458291(transcript)|uniprotkb:Q8TC20-4(isoform-parent)|entrezgene/locuslink:285782(identity)	-	-	isoform-comment:No experimental confirmation available. May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:+5KU/P9FeqlhSbGhpYJ1V6DqQNg559292	rogid:rbycl1bawuMuBA8D5NfrekzCADM9606	intact-crc:D733546863EF99FD|rigid:m8EFDhKq0op7IB8ISGsuBL8uk4s	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O13566	uniprotkb:O14964	intact:EBI-29708|ensemblfungi:YPR123C	intact:EBI-740220|uniprotkb:Q9NR36|ensembl:ENSP00000331201|ensembl:ENSP00000504106	psi-mi:yp123_yeast(display_long)|uniprotkb:P9642.4B(orf name)|uniprotkb:YPR123C(locus name)	psi-mi:hgs_human(display_long)|uniprotkb:Protein pp110(gene name synonym)|uniprotkb:Hrs(gene name synonym)|uniprotkb:HGS(gene name)|psi-mi:HGS(display_short)|uniprotkb:HRS(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11522687|imex:IM-24995-45	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000006327|dip:DIP-3811N|ensemblfungi:YPR123C(gene)|ensemblfungi:YPR123C_mRNA(transcript)|go:"GO:0016021"(integral component of membrane)|sgd:YPR123C(identity)	refseq:NP_004703.1|dip:DIP-29050N|ensembl:ENSG00000185359(gene)|ensembl:ENST00000329138(transcript)|ensembl:ENST00000676546(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0007165"(signal transduction)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010324"(membrane invagination)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010642"(negative regulation of platelet-derived growth factor receptor signaling pathway)|go:"GO:0016197"(endosomal transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032585"(multivesicular body membrane)|go:"GO:0033565"(ESCRT-0 complex)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043405"(regulation of MAP kinase activity)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072657"(protein localization to membrane)|go:"GO:0097013"(phagocytic vesicle lumen)|go:"GO:1903543"(positive regulation of exosomal secretion)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR002014(VHS)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017073(Ubiquitin binding protein, Hrs/VPS27)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR024641|mint:O14964|rcsb pdb:2D3G|rcsb pdb:3F1I|rcsb pdb:3OBQ|rcsb pdb:3ZYQ|rcsb pdb:4AVX|reactome:R-HSA-182971|reactome:R-HSA-432720|reactome:R-HSA-5689880|reactome:R-HSA-6807004|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8875360|reactome:R-HSA-9013420|reactome:R-HSA-917729|reactome:R-HSA-9635644|reactome:R-HSA-9636383|reactome:R-HSA-9706019|entrezgene/locuslink:9146(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:tb84y2TgUcLXIj6zwqC/7T8QHKg559292	rogid:z/AnREuqEpyJ9/Zj6JFCJCJem1I9606	intact-crc:8931FAFE68894DE1|rigid:Rl06iksuRyNqdidnPspyEoRr7kI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O13539	uniprotkb:O14964	intact:EBI-30898|uniprotkb:D3DLB6|ensemblfungi:YHR167W	intact:EBI-740220|uniprotkb:Q9NR36|ensembl:ENSP00000331201|ensembl:ENSP00000504106	psi-mi:thp2_yeast(display_long)|uniprotkb:THP2(gene name)|psi-mi:THP2(display_short)|uniprotkb:YHR167W(locus name)	psi-mi:hgs_human(display_long)|uniprotkb:Protein pp110(gene name synonym)|uniprotkb:Hrs(gene name synonym)|uniprotkb:HGS(gene name)|psi-mi:HGS(display_short)|uniprotkb:HRS(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11522649|imex:IM-24995-41	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012037.1|sgd:S000001210|dip:DIP-4246N|mint:O13539|ensemblfungi:YHR167W(gene)|ensemblfungi:YHR167W_mRNA(transcript)|go:"GO:0000445"(THO complex part of transcription export complex)|go:"GO:0000446"(nucleoplasmic THO complex)|go:"GO:0000723"(telomere maintenance)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0006310"(DNA recombination)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0034063"(stress granule assembly)|interpro:IPR018557|rcsb pdb:7APX|rcsb pdb:7LUV|sgd:YHR167W(identity)	refseq:NP_004703.1|dip:DIP-29050N|ensembl:ENSG00000185359(gene)|ensembl:ENST00000329138(transcript)|ensembl:ENST00000676546(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0007165"(signal transduction)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010324"(membrane invagination)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010642"(negative regulation of platelet-derived growth factor receptor signaling pathway)|go:"GO:0016197"(endosomal transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032585"(multivesicular body membrane)|go:"GO:0033565"(ESCRT-0 complex)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043405"(regulation of MAP kinase activity)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072657"(protein localization to membrane)|go:"GO:0097013"(phagocytic vesicle lumen)|go:"GO:1903543"(positive regulation of exosomal secretion)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR002014(VHS)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017073(Ubiquitin binding protein, Hrs/VPS27)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR024641|mint:O14964|rcsb pdb:2D3G|rcsb pdb:3F1I|rcsb pdb:3OBQ|rcsb pdb:3ZYQ|rcsb pdb:4AVX|reactome:R-HSA-182971|reactome:R-HSA-432720|reactome:R-HSA-5689880|reactome:R-HSA-6807004|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8875360|reactome:R-HSA-9013420|reactome:R-HSA-917729|reactome:R-HSA-9635644|reactome:R-HSA-9636383|reactome:R-HSA-9706019|entrezgene/locuslink:9146(identity)	-	crc64:16EFA6F464507C57	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:SaTSL6jLwX1hTVCqvU8ZNR96r8U559292	rogid:z/AnREuqEpyJ9/Zj6JFCJCJem1I9606	intact-crc:CE22320CF4577252|rigid:UC+FrYLu9HP0ocapfmrftA9xbGU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q15834	uniprotkb:O13539	intact:EBI-739674|uniprotkb:Q96HA0|uniprotkb:B2R598|ensembl:ENSP00000311695	intact:EBI-30898|uniprotkb:D3DLB6|ensemblfungi:YHR167W	psi-mi:cc85b_human(display_long)|uniprotkb:CCDC85B(gene name)|psi-mi:CCDC85B(display_short)|uniprotkb:Hepatitis delta antigen-interacting protein A(gene name synonym)|uniprotkb:DIPA(gene name synonym)	psi-mi:thp2_yeast(display_long)|uniprotkb:THP2(gene name)|psi-mi:THP2(display_short)|uniprotkb:YHR167W(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11522667|imex:IM-24995-43	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006839.2|ensembl:ENSG00000175602(gene)|ensembl:ENST00000312579(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005912"(adherens junction)|go:"GO:0030154"(cell differentiation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0070097"(delta-catenin binding)|interpro:IPR019359|entrezgene/locuslink:11007(identity)	refseq:NP_012037.1|sgd:S000001210|dip:DIP-4246N|mint:O13539|ensemblfungi:YHR167W(gene)|ensemblfungi:YHR167W_mRNA(transcript)|go:"GO:0000445"(THO complex part of transcription export complex)|go:"GO:0000446"(nucleoplasmic THO complex)|go:"GO:0000723"(telomere maintenance)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0006310"(DNA recombination)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0034063"(stress granule assembly)|interpro:IPR018557|rcsb pdb:7APX|rcsb pdb:7LUV|sgd:YHR167W(identity)	-	-	crc64:16EFA6F464507C57	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:DUMY8gDRLRjC4Iu+z7SVBZ6sQkY9606	rogid:SaTSL6jLwX1hTVCqvU8ZNR96r8U559292	intact-crc:AF5F1D13E066B22D|rigid:P/TDjEqBpyXpQmTQQPkNo6/Nytc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P43365	uniprotkb:O13539	intact:EBI-749530|uniprotkb:Q9NSD3|intact:EBI-10178394|uniprotkb:Q6FHH8|ensembl:ENSP00000350592|ensembl:ENSP00000377447|ensembl:ENSP00000377478	intact:EBI-30898|uniprotkb:D3DLB6|ensemblfungi:YHR167W	psi-mi:magac_human(display_long)|uniprotkb:MAGE-12 antigen(gene name synonym)|uniprotkb:MAGE12F antigen(gene name synonym)|uniprotkb:Cancer/testis antigen 1.12(gene name synonym)|uniprotkb:MAGEA12(gene name)|psi-mi:MAGEA12(display_short)|uniprotkb:MAGE12(gene name synonym)	psi-mi:thp2_yeast(display_long)|uniprotkb:THP2(gene name)|psi-mi:THP2(display_short)|uniprotkb:YHR167W(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11522658|imex:IM-24995-42	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001159858.1|refseq:NP_001159859.1|refseq:NP_005358.2|ensembl:ENSG00000213401(gene)|ensembl:ENST00000357916(transcript)|ensembl:ENST00000393869(transcript)|ensembl:ENST00000393900(transcript)|interpro:IPR002190(MAGE protein)|interpro:IPR021072|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|entrezgene/locuslink:4111(identity)	refseq:NP_012037.1|sgd:S000001210|dip:DIP-4246N|mint:O13539|ensemblfungi:YHR167W(gene)|ensemblfungi:YHR167W_mRNA(transcript)|go:"GO:0000445"(THO complex part of transcription export complex)|go:"GO:0000446"(nucleoplasmic THO complex)|go:"GO:0000723"(telomere maintenance)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0006310"(DNA recombination)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0034063"(stress granule assembly)|interpro:IPR018557|rcsb pdb:7APX|rcsb pdb:7LUV|sgd:YHR167W(identity)	-	-	crc64:16EFA6F464507C57	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:3/Jxz2VsFOb67RWqWj3xbTrw3s49606	rogid:SaTSL6jLwX1hTVCqvU8ZNR96r8U559292	intact-crc:2B0DAF9760FDA379|rigid:Jen9lZoSJESpiOwO7zbT6YrU1sw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O13541	uniprotkb:Q96ED9-2	intact:EBI-11522678|ensemblfungi:YLR280C	intact:EBI-10961706|ensembl:ENSP00000264827	psi-mi:yl280_yeast(display_long)|uniprotkb:YLR280C(locus name)	psi-mi:q96ed9-2(display_long)|uniprotkb:HOOK2(gene name)|psi-mi:HOOK2(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11522676|imex:IM-24995-44	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YLR280C(gene)|ensemblfungi:YLR280C_mRNA(transcript)|sgd:S000004270|sgd:YLR280C(identity)	ensembl:ENSG00000095066(gene)|ensembl:ENST00000264827(transcript)|intact:EBI-743290(isoform-parent)|uniprotkb:Q96ED9-2(isoform-parent)|entrezgene/locuslink:29911(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/03/16	rogid:tBIn1i72eUTn5Ht00WY4yxkAAFU559292	rogid:aJZ/iDJpRk5dFL1NiouLuTjnOnc9606	intact-crc:BF89B5BB8DE43791|rigid:Zg6EYZUtXKY0+thghDqrLPJuSnw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P00431	uniprotkb:Q969L2	intact:EBI-4389|uniprotkb:Q6Q5M9|uniprotkb:D6VXC7|ensemblfungi:YKR066C	intact:EBI-944295|uniprotkb:Q6ZMD9|uniprotkb:B2R520|ensembl:ENSP00000479708	psi-mi:ccpr_yeast(display_long)|uniprotkb:CCP1(gene name)|psi-mi:CCP1(display_short)|uniprotkb:CCP(gene name synonym)|uniprotkb:CPO(gene name synonym)|uniprotkb:YKR066C(locus name)	psi-mi:mal2_human(display_long)|uniprotkb:MAL2(gene name)|psi-mi:MAL2(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11522771|imex:IM-24995-53	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012992.1|sgd:S000001774|dip:DIP-6251N|ensemblfungi:YKR066C(gene)|ensemblfungi:YKR066C_mRNA(transcript)|go:"GO:0000302"(response to reactive oxygen species)|go:"GO:0004130"(cytochrome-c peroxidase activity)|go:"GO:0004601"(peroxidase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0020037"(heme binding)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0046872"(metal ion binding)|interpro:IPR002016(Haem peroxidase, plant/fungal/bacterial)|interpro:IPR002207(Plant ascorbate peroxidase)|interpro:IPR010255(Haem peroxidase)|interpro:IPR019793|interpro:IPR019794|interpro:IPR044831|rcsb pdb:1A2F|rcsb pdb:1A2G|rcsb pdb:1AA4|rcsb pdb:1AC4|rcsb pdb:1AC8|rcsb pdb:1AEB|rcsb pdb:1AED|rcsb pdb:1AEE|rcsb pdb:1AEF|rcsb pdb:1AEG|rcsb pdb:1AEH|rcsb pdb:1AEJ|rcsb pdb:1AEK|rcsb pdb:1AEM|rcsb pdb:1AEN|rcsb pdb:1AEO|rcsb pdb:1AEQ|rcsb pdb:1AES|rcsb pdb:1AET|rcsb pdb:1AEU|rcsb pdb:1AEV|rcsb pdb:1BEJ|rcsb pdb:1BEK|rcsb pdb:1BEM|rcsb pdb:1BEP|rcsb pdb:1BEQ|rcsb pdb:1BES|rcsb pdb:1BJ9|rcsb pdb:1BVA|rcsb pdb:1CCA|rcsb pdb:1CCB|rcsb pdb:1CCC|rcsb pdb:1CCE|rcsb pdb:1CCG|rcsb pdb:1CCI|rcsb pdb:1CCJ|rcsb pdb:1CCK|rcsb pdb:1CCL|rcsb pdb:1CCP|rcsb pdb:1CMP|rcsb pdb:1CMQ|rcsb pdb:1CMT|rcsb pdb:1CPD|rcsb pdb:1CPE|rcsb pdb:1CPF|rcsb pdb:1CPG|rcsb pdb:1CYF|rcsb pdb:1DCC|rcsb pdb:1DJ1|rcsb pdb:1DJ5|rcsb pdb:1DS4|rcsb pdb:1DSE|rcsb pdb:1DSG|rcsb pdb:1DSO|rcsb pdb:1DSP|rcsb pdb:1EBE|rcsb pdb:1JCI|rcsb pdb:1JDR|rcsb pdb:1KOK|rcsb pdb:1KRJ|rcsb pdb:1KXM|rcsb pdb:1KXN|rcsb pdb:1MK8|rcsb pdb:1MKQ|rcsb pdb:1MKR|rcsb pdb:1ML2|rcsb pdb:1RYC|rcsb pdb:1S6V|rcsb pdb:1S73|rcsb pdb:1SBM|rcsb pdb:1SDQ|rcsb pdb:1SOG|rcsb pdb:1STQ|rcsb pdb:1U74|rcsb pdb:1U75|rcsb pdb:1Z53|rcsb pdb:1ZBY|rcsb pdb:1ZBZ|rcsb pdb:2ANZ|rcsb pdb:2AQD|rcsb pdb:2AS1|rcsb pdb:2AS2|rcsb pdb:2AS3|rcsb pdb:2AS4|rcsb pdb:2AS6|rcsb pdb:2B0Z|rcsb pdb:2B10|rcsb pdb:2B11|rcsb pdb:2B12|rcsb pdb:2BCN|rcsb pdb:2CCP|rcsb pdb:2CEP|rcsb pdb:2CYP|rcsb pdb:2EUN|rcsb pdb:2EUO|rcsb pdb:2EUP|rcsb pdb:2EUQ|rcsb pdb:2EUR|rcsb pdb:2EUS|rcsb pdb:2EUT|rcsb pdb:2EUU|rcsb pdb:2GB8|rcsb pdb:2IA8|rcsb pdb:2ICV|rcsb pdb:2JTI|rcsb pdb:2N18|rcsb pdb:2PCB|rcsb pdb:2PCC|rcsb pdb:2RBT|rcsb pdb:2RBU|rcsb pdb:2RBV|rcsb pdb:2RBW|rcsb pdb:2RBX|rcsb pdb:2RBY|rcsb pdb:2RBZ|rcsb pdb:2RC0|rcsb pdb:2RC1|rcsb pdb:2RC2|rcsb pdb:2V23|rcsb pdb:2V2E|rcsb pdb:2X07|rcsb pdb:2X08|rcsb pdb:2XIL|rcsb pdb:2XJ5|rcsb pdb:2XJ8|rcsb pdb:2Y5A|rcsb pdb:2YCG|rcsb pdb:3CCP|rcsb pdb:3CCX|rcsb pdb:3E2N|rcsb pdb:3E2O|rcsb pdb:3EXB|rcsb pdb:3M23|rcsb pdb:3M25|rcsb pdb:3M26|rcsb pdb:3M27|rcsb pdb:3M28|rcsb pdb:3M29|rcsb pdb:3M2A|rcsb pdb:1CMU|rcsb pdb:3M2B|rcsb pdb:3M2C|rcsb pdb:3M2D|rcsb pdb:3M2E|rcsb pdb:3M2F|rcsb pdb:3M2G|rcsb pdb:3M2H|rcsb pdb:3M2I|rcsb pdb:3R98|rcsb pdb:3R99|rcsb pdb:4A6Z|rcsb pdb:4A71|rcsb pdb:4A78|rcsb pdb:4A7M|rcsb pdb:4CCP|rcsb pdb:4CCX|rcsb pdb:4CVI|rcsb pdb:4CVJ|rcsb pdb:4JB4|rcsb pdb:4NFG|rcsb pdb:4P4Q|rcsb pdb:4XV4|rcsb pdb:4XV5|rcsb pdb:4XV6|rcsb pdb:4XV7|rcsb pdb:4XV8|rcsb pdb:4XVA|rcsb pdb:5CCP|rcsb pdb:5CIB|rcsb pdb:5CIC|rcsb pdb:5CID|rcsb pdb:5CIE|rcsb pdb:5CIF|rcsb pdb:5CIG|rcsb pdb:5CIH|rcsb pdb:5D6M|rcsb pdb:5EJT|rcsb pdb:5EJX|rcsb pdb:6CCP|rcsb pdb:6H08|rcsb pdb:6P41|rcsb pdb:6P42|rcsb pdb:6P43|rcsb pdb:6Y1T|rcsb pdb:6Y2Y|rcsb pdb:7CCP|sgd:YKR066C(identity)	refseq:NP_443118.1|ensembl:ENSG00000147676(gene)|ensembl:ENST00000614891(transcript)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019911"(structural constituent of myelin sheath)|go:"GO:0042552"(myelination)|go:"GO:0045056"(transcytosis)|go:"GO:0045121"(membrane raft)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|interpro:IPR008253(Marvel)|interpro:IPR013295("Myelin and lymphocyte (MAL)")|interpro:IPR033240|entrezgene/locuslink:114569(identity)	-	crc64:A5D26385DA6F0A0B	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:LkPXY1wuYoCFzMQPSsAtXZrRi8w559292	rogid:7SApzrGTzj8V3GIwkdO0X/z6geg9606	intact-crc:A359E030ADD510F1|rigid:BmiQ9cVqnLWMzah7G4aLQsu7hF4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P00431	uniprotkb:Q6RW13-2	intact:EBI-4389|uniprotkb:Q6Q5M9|uniprotkb:D6VXC7|ensemblfungi:YKR066C	intact:EBI-11522760|ensembl:ENSP00000365816	psi-mi:ccpr_yeast(display_long)|uniprotkb:CCP1(gene name)|psi-mi:CCP1(display_short)|uniprotkb:CCP(gene name synonym)|uniprotkb:CPO(gene name synonym)|uniprotkb:YKR066C(locus name)	psi-mi:q6rw13-2(display_long)|uniprotkb:AGTRAP(gene name)|psi-mi:AGTRAP(display_short)|uniprotkb:AT1 receptor-associated protein(gene name synonym)|uniprotkb:ATRAP(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11522758|imex:IM-24995-52	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012992.1|sgd:S000001774|dip:DIP-6251N|ensemblfungi:YKR066C(gene)|ensemblfungi:YKR066C_mRNA(transcript)|go:"GO:0000302"(response to reactive oxygen species)|go:"GO:0004130"(cytochrome-c peroxidase activity)|go:"GO:0004601"(peroxidase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0020037"(heme binding)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0046872"(metal ion binding)|interpro:IPR002016(Haem peroxidase, plant/fungal/bacterial)|interpro:IPR002207(Plant ascorbate peroxidase)|interpro:IPR010255(Haem peroxidase)|interpro:IPR019793|interpro:IPR019794|interpro:IPR044831|rcsb pdb:1A2F|rcsb pdb:1A2G|rcsb pdb:1AA4|rcsb pdb:1AC4|rcsb pdb:1AC8|rcsb pdb:1AEB|rcsb pdb:1AED|rcsb pdb:1AEE|rcsb pdb:1AEF|rcsb pdb:1AEG|rcsb pdb:1AEH|rcsb pdb:1AEJ|rcsb pdb:1AEK|rcsb pdb:1AEM|rcsb pdb:1AEN|rcsb pdb:1AEO|rcsb pdb:1AEQ|rcsb pdb:1AES|rcsb pdb:1AET|rcsb pdb:1AEU|rcsb pdb:1AEV|rcsb pdb:1BEJ|rcsb pdb:1BEK|rcsb pdb:1BEM|rcsb pdb:1BEP|rcsb pdb:1BEQ|rcsb pdb:1BES|rcsb pdb:1BJ9|rcsb pdb:1BVA|rcsb pdb:1CCA|rcsb pdb:1CCB|rcsb pdb:1CCC|rcsb pdb:1CCE|rcsb pdb:1CCG|rcsb pdb:1CCI|rcsb pdb:1CCJ|rcsb pdb:1CCK|rcsb pdb:1CCL|rcsb pdb:1CCP|rcsb pdb:1CMP|rcsb pdb:1CMQ|rcsb pdb:1CMT|rcsb pdb:1CPD|rcsb pdb:1CPE|rcsb pdb:1CPF|rcsb pdb:1CPG|rcsb pdb:1CYF|rcsb pdb:1DCC|rcsb pdb:1DJ1|rcsb pdb:1DJ5|rcsb pdb:1DS4|rcsb pdb:1DSE|rcsb pdb:1DSG|rcsb pdb:1DSO|rcsb pdb:1DSP|rcsb pdb:1EBE|rcsb pdb:1JCI|rcsb pdb:1JDR|rcsb pdb:1KOK|rcsb pdb:1KRJ|rcsb pdb:1KXM|rcsb pdb:1KXN|rcsb pdb:1MK8|rcsb pdb:1MKQ|rcsb pdb:1MKR|rcsb pdb:1ML2|rcsb pdb:1RYC|rcsb pdb:1S6V|rcsb pdb:1S73|rcsb pdb:1SBM|rcsb pdb:1SDQ|rcsb pdb:1SOG|rcsb pdb:1STQ|rcsb pdb:1U74|rcsb pdb:1U75|rcsb pdb:1Z53|rcsb pdb:1ZBY|rcsb pdb:1ZBZ|rcsb pdb:2ANZ|rcsb pdb:2AQD|rcsb pdb:2AS1|rcsb pdb:2AS2|rcsb pdb:2AS3|rcsb pdb:2AS4|rcsb pdb:2AS6|rcsb pdb:2B0Z|rcsb pdb:2B10|rcsb pdb:2B11|rcsb pdb:2B12|rcsb pdb:2BCN|rcsb pdb:2CCP|rcsb pdb:2CEP|rcsb pdb:2CYP|rcsb pdb:2EUN|rcsb pdb:2EUO|rcsb pdb:2EUP|rcsb pdb:2EUQ|rcsb pdb:2EUR|rcsb pdb:2EUS|rcsb pdb:2EUT|rcsb pdb:2EUU|rcsb pdb:2GB8|rcsb pdb:2IA8|rcsb pdb:2ICV|rcsb pdb:2JTI|rcsb pdb:2N18|rcsb pdb:2PCB|rcsb pdb:2PCC|rcsb pdb:2RBT|rcsb pdb:2RBU|rcsb pdb:2RBV|rcsb pdb:2RBW|rcsb pdb:2RBX|rcsb pdb:2RBY|rcsb pdb:2RBZ|rcsb pdb:2RC0|rcsb pdb:2RC1|rcsb pdb:2RC2|rcsb pdb:2V23|rcsb pdb:2V2E|rcsb pdb:2X07|rcsb pdb:2X08|rcsb pdb:2XIL|rcsb pdb:2XJ5|rcsb pdb:2XJ8|rcsb pdb:2Y5A|rcsb pdb:2YCG|rcsb pdb:3CCP|rcsb pdb:3CCX|rcsb pdb:3E2N|rcsb pdb:3E2O|rcsb pdb:3EXB|rcsb pdb:3M23|rcsb pdb:3M25|rcsb pdb:3M26|rcsb pdb:3M27|rcsb pdb:3M28|rcsb pdb:3M29|rcsb pdb:3M2A|rcsb pdb:1CMU|rcsb pdb:3M2B|rcsb pdb:3M2C|rcsb pdb:3M2D|rcsb pdb:3M2E|rcsb pdb:3M2F|rcsb pdb:3M2G|rcsb pdb:3M2H|rcsb pdb:3M2I|rcsb pdb:3R98|rcsb pdb:3R99|rcsb pdb:4A6Z|rcsb pdb:4A71|rcsb pdb:4A78|rcsb pdb:4A7M|rcsb pdb:4CCP|rcsb pdb:4CCX|rcsb pdb:4CVI|rcsb pdb:4CVJ|rcsb pdb:4JB4|rcsb pdb:4NFG|rcsb pdb:4P4Q|rcsb pdb:4XV4|rcsb pdb:4XV5|rcsb pdb:4XV6|rcsb pdb:4XV7|rcsb pdb:4XV8|rcsb pdb:4XVA|rcsb pdb:5CCP|rcsb pdb:5CIB|rcsb pdb:5CIC|rcsb pdb:5CID|rcsb pdb:5CIE|rcsb pdb:5CIF|rcsb pdb:5CIG|rcsb pdb:5CIH|rcsb pdb:5D6M|rcsb pdb:5EJT|rcsb pdb:5EJX|rcsb pdb:6CCP|rcsb pdb:6H08|rcsb pdb:6P41|rcsb pdb:6P42|rcsb pdb:6P43|rcsb pdb:6Y1T|rcsb pdb:6Y2Y|rcsb pdb:7CCP|sgd:YKR066C(identity)	ensembl:ENSG00000177674(gene)|ensembl:ENST00000376629(transcript)|intact:EBI-741181(isoform-parent)|uniprotkb:Q6RW13-2(isoform-parent)|entrezgene/locuslink:57085(identity)	-	crc64:A5D26385DA6F0A0B	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:LkPXY1wuYoCFzMQPSsAtXZrRi8w559292	rogid:PNzVis/8puQZBJ562gCqZKc078s9606	intact-crc:9741BA8F31DB0ACE|rigid:5UDqt3eotijjhpIZik/N0KGkdIo	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O14468	uniprotkb:Q9BYV6-2	intact:EBI-2343965|uniprotkb:D6W304|ensemblfungi:YOR304C-A	intact:EBI-11522718|ensembl:ENSP00000297348	psi-mi:yo304_yeast(display_long)|uniprotkb:YOR304C-A(locus name)	psi-mi:q9byv6-2(display_long)|uniprotkb:TRIM55(gene name)|psi-mi:TRIM55(display_short)|uniprotkb:MURF2(gene name synonym)|uniprotkb:Muscle-specific RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 29(gene name synonym)|uniprotkb:RNF29(gene name synonym)|uniprotkb:p50(isoform synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11522722|imex:IM-24995-48	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005830|refseq:NP_014949.3|mint:O14468|ensemblfungi:YOR304C-A(gene)|ensemblfungi:YOR304C-A_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005933"(cellular bud)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0043332"(mating projection tip)|go:"GO:0051017"(actin filament bundle assembly)|sgd:YOR304C-A(identity)	intact:EBI-2341179(isoform-parent)|uniprotkb:Q9BYV6-2(isoform-parent)|ensembl:ENSG00000147573(gene)|ensembl:ENST00000353317(transcript)|entrezgene/locuslink:84675(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:+5KU/P9FeqlhSbGhpYJ1V6DqQNg559292	rogid:9t8UhK+Z1yBqjnQrOqPD76NuXGg9606	intact-crc:0C5998E417D3A932|rigid:psr/fBzv8+d0CL4Ih+FUBQXeXww	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P00330	uniprotkb:Q15645	intact:EBI-2218|uniprotkb:D6W1Y3|ensemblfungi:YOL086C	intact:EBI-358993|uniprotkb:C9K0T3|uniprotkb:O15324|ensembl:ENSP00000166345|uniprotkb:D3DTC0	psi-mi:adh1_yeast(display_long)|uniprotkb:ADH1(gene name)|psi-mi:ADH1(display_short)|uniprotkb:ADC1(gene name synonym)|uniprotkb:YOL086C(locus name)|uniprotkb:O0947(orf name)|uniprotkb:Alcohol dehydrogenase I(gene name synonym)|uniprotkb:YADH-1(gene name synonym)	psi-mi:pch2_human(display_long)|uniprotkb:TRIP13(gene name)|psi-mi:TRIP13(display_short)|uniprotkb:Thyroid receptor-interacting protein 13(gene name synonym)|uniprotkb:PCH2(gene name synonym)|uniprotkb:Thyroid hormone receptor interactor 13(gene name synonym)|uniprotkb:Human papillomavirus type 16 E1 protein-binding protein(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11522740|imex:IM-24995-50	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014555.1|sgd:S000005446|dip:DIP-1143N|mint:P00330|ensemblfungi:YOL086C(gene)|ensemblfungi:YOL086C_mRNA(transcript)|go:"GO:0000947"(amino acid catabolic process to alcohol via Ehrlich pathway)|go:"GO:0004022"("alcohol dehydrogenase (NAD+) activity")|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006116"(NADH oxidation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019170"("methylglyoxal reductase (NADH-dependent) activity")|go:"GO:0042802"(identical protein binding)|go:"GO:0043458"(ethanol biosynthetic process involved in glucose fermentation to ethanol)|go:"GO:0045069"(regulation of viral genome replication)|go:"GO:0046809"(replication compartment)|go:"GO:1904408"(melatonin binding)|interpro:IPR002328(Alcohol dehydrogenase, zinc-containing, conserved site)|interpro:IPR011032(GroES-like)|interpro:IPR013149(Alcohol dehydrogenase, zinc-binding)|interpro:IPR013154(Alcohol dehydrogenase GroES-like)|interpro:IPR020843|interpro:IPR036291|rcsb pdb:4W6Z|rcsb pdb:5ENV|sgd:YOL086C(identity)	refseq:NP_004228.1|ensembl:ENSG00000071539(gene)|ensembl:ENST00000166345(transcript)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|refseq:XP_011512465.1|dip:DIP-34493N|go:"GO:0005694"(chromosome)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0007141"(male meiosis I)|go:"GO:0007144"(female meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007286"(spermatid development)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051598"(meiotic recombination checkpoint signaling)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR027417|interpro:IPR044539|mint:Q15645|rcsb pdb:5VQ9|rcsb pdb:5VQA|rcsb pdb:5WC2|rcsb pdb:6F0X|rcsb pdb:6LK0|rcsb pdb:7L9P|entrezgene/locuslink:9319(identity)	-	crc64:F14AE24B5D8D12A5	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:ud0TIPDwB9vm9Ug9a5a4wY20oZ8559292	rogid:heF2f3R2lGIpZ80mZHnhMktXTE49606	intact-crc:16E310489FFC8969|rigid:84bDhYeVJEiw569dEKt/iNyltFs	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O14468	uniprotkb:Q9P2A4	intact:EBI-2343965|uniprotkb:D6W304|ensemblfungi:YOR304C-A	intact:EBI-742038|uniprotkb:C9IZN8|ensembl:ENSP00000225941|uniprotkb:Q9H0P6	psi-mi:yo304_yeast(display_long)|uniprotkb:YOR304C-A(locus name)	psi-mi:abi3_human(display_long)|uniprotkb:New molecule including SH3(gene name synonym)|uniprotkb:ABI3(gene name)|psi-mi:ABI3(display_short)|uniprotkb:NESH(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11522731|imex:IM-24995-49	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005830|refseq:NP_014949.3|mint:O14468|ensemblfungi:YOR304C-A(gene)|ensemblfungi:YOR304C-A_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005933"(cellular bud)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0043332"(mating projection tip)|go:"GO:0051017"(actin filament bundle assembly)|sgd:YOR304C-A(identity)	refseq:NP_001128658.1|refseq:NP_057512.1|ensembl:ENSG00000108798(gene)|ensembl:ENST00000225941(transcript)|go:"GO:0002357"(defense response to tumor cell)|go:"GO:0005737"(cytoplasm)|go:"GO:0010593"(negative regulation of lamellipodium assembly)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031209"(SCAR complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0051015"(actin filament binding)|go:"GO:0061001"(regulation of dendritic spine morphogenesis)|go:"GO:0099151"(regulation of postsynaptic density assembly)|go:"GO:1900028"(negative regulation of ruffle assembly)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|go:"GO:2000249"(regulation of actin cytoskeleton reorganization)|go:"GO:2000774"(positive regulation of cellular senescence)|interpro:IPR001452(Src homology-3)|interpro:IPR012849(Abl-interactor, homeo-domain homologous region)|interpro:IPR028455|interpro:IPR028457|interpro:IPR036028|mint:Q9P2A4|entrezgene/locuslink:51225(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:+5KU/P9FeqlhSbGhpYJ1V6DqQNg559292	rogid:VAjz40ulLa5L+GmfL7ia5wTDND49606	intact-crc:59CA180B3C257BD3|rigid:SQBbXoZnK7LCw4iWRo2H61tTfMM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P00431	uniprotkb:P43355	intact:EBI-4389|uniprotkb:Q6Q5M9|uniprotkb:D6VXC7|ensemblfungi:YKR066C	intact:EBI-740978|ensembl:ENSP00000349085|uniprotkb:O00346|uniprotkb:B2RC81	psi-mi:ccpr_yeast(display_long)|uniprotkb:CCP1(gene name)|psi-mi:CCP1(display_short)|uniprotkb:CCP(gene name synonym)|uniprotkb:CPO(gene name synonym)|uniprotkb:YKR066C(locus name)	psi-mi:maga1_human(display_long)|uniprotkb:MAGE-1 antigen(gene name synonym)|uniprotkb:Antigen MZ2-E(gene name synonym)|uniprotkb:Cancer/testis antigen 1.1(gene name synonym)|uniprotkb:MAGEA1(gene name)|psi-mi:MAGEA1(display_short)|uniprotkb:MAGE1(gene name synonym)|uniprotkb:MAGE1A(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11522749|imex:IM-24995-51	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012992.1|sgd:S000001774|dip:DIP-6251N|ensemblfungi:YKR066C(gene)|ensemblfungi:YKR066C_mRNA(transcript)|go:"GO:0000302"(response to reactive oxygen species)|go:"GO:0004130"(cytochrome-c peroxidase activity)|go:"GO:0004601"(peroxidase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0020037"(heme binding)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0046872"(metal ion binding)|interpro:IPR002016(Haem peroxidase, plant/fungal/bacterial)|interpro:IPR002207(Plant ascorbate peroxidase)|interpro:IPR010255(Haem peroxidase)|interpro:IPR019793|interpro:IPR019794|interpro:IPR044831|rcsb pdb:1A2F|rcsb pdb:1A2G|rcsb pdb:1AA4|rcsb pdb:1AC4|rcsb pdb:1AC8|rcsb pdb:1AEB|rcsb pdb:1AED|rcsb pdb:1AEE|rcsb pdb:1AEF|rcsb pdb:1AEG|rcsb pdb:1AEH|rcsb pdb:1AEJ|rcsb pdb:1AEK|rcsb pdb:1AEM|rcsb pdb:1AEN|rcsb pdb:1AEO|rcsb pdb:1AEQ|rcsb pdb:1AES|rcsb pdb:1AET|rcsb pdb:1AEU|rcsb pdb:1AEV|rcsb pdb:1BEJ|rcsb pdb:1BEK|rcsb pdb:1BEM|rcsb pdb:1BEP|rcsb pdb:1BEQ|rcsb pdb:1BES|rcsb pdb:1BJ9|rcsb pdb:1BVA|rcsb pdb:1CCA|rcsb pdb:1CCB|rcsb pdb:1CCC|rcsb pdb:1CCE|rcsb pdb:1CCG|rcsb pdb:1CCI|rcsb pdb:1CCJ|rcsb pdb:1CCK|rcsb pdb:1CCL|rcsb pdb:1CCP|rcsb pdb:1CMP|rcsb pdb:1CMQ|rcsb pdb:1CMT|rcsb pdb:1CPD|rcsb pdb:1CPE|rcsb pdb:1CPF|rcsb pdb:1CPG|rcsb pdb:1CYF|rcsb pdb:1DCC|rcsb pdb:1DJ1|rcsb pdb:1DJ5|rcsb pdb:1DS4|rcsb pdb:1DSE|rcsb pdb:1DSG|rcsb pdb:1DSO|rcsb pdb:1DSP|rcsb pdb:1EBE|rcsb pdb:1JCI|rcsb pdb:1JDR|rcsb pdb:1KOK|rcsb pdb:1KRJ|rcsb pdb:1KXM|rcsb pdb:1KXN|rcsb pdb:1MK8|rcsb pdb:1MKQ|rcsb pdb:1MKR|rcsb pdb:1ML2|rcsb pdb:1RYC|rcsb pdb:1S6V|rcsb pdb:1S73|rcsb pdb:1SBM|rcsb pdb:1SDQ|rcsb pdb:1SOG|rcsb pdb:1STQ|rcsb pdb:1U74|rcsb pdb:1U75|rcsb pdb:1Z53|rcsb pdb:1ZBY|rcsb pdb:1ZBZ|rcsb pdb:2ANZ|rcsb pdb:2AQD|rcsb pdb:2AS1|rcsb pdb:2AS2|rcsb pdb:2AS3|rcsb pdb:2AS4|rcsb pdb:2AS6|rcsb pdb:2B0Z|rcsb pdb:2B10|rcsb pdb:2B11|rcsb pdb:2B12|rcsb pdb:2BCN|rcsb pdb:2CCP|rcsb pdb:2CEP|rcsb pdb:2CYP|rcsb pdb:2EUN|rcsb pdb:2EUO|rcsb pdb:2EUP|rcsb pdb:2EUQ|rcsb pdb:2EUR|rcsb pdb:2EUS|rcsb pdb:2EUT|rcsb pdb:2EUU|rcsb pdb:2GB8|rcsb pdb:2IA8|rcsb pdb:2ICV|rcsb pdb:2JTI|rcsb pdb:2N18|rcsb pdb:2PCB|rcsb pdb:2PCC|rcsb pdb:2RBT|rcsb pdb:2RBU|rcsb pdb:2RBV|rcsb pdb:2RBW|rcsb pdb:2RBX|rcsb pdb:2RBY|rcsb pdb:2RBZ|rcsb pdb:2RC0|rcsb pdb:2RC1|rcsb pdb:2RC2|rcsb pdb:2V23|rcsb pdb:2V2E|rcsb pdb:2X07|rcsb pdb:2X08|rcsb pdb:2XIL|rcsb pdb:2XJ5|rcsb pdb:2XJ8|rcsb pdb:2Y5A|rcsb pdb:2YCG|rcsb pdb:3CCP|rcsb pdb:3CCX|rcsb pdb:3E2N|rcsb pdb:3E2O|rcsb pdb:3EXB|rcsb pdb:3M23|rcsb pdb:3M25|rcsb pdb:3M26|rcsb pdb:3M27|rcsb pdb:3M28|rcsb pdb:3M29|rcsb pdb:3M2A|rcsb pdb:1CMU|rcsb pdb:3M2B|rcsb pdb:3M2C|rcsb pdb:3M2D|rcsb pdb:3M2E|rcsb pdb:3M2F|rcsb pdb:3M2G|rcsb pdb:3M2H|rcsb pdb:3M2I|rcsb pdb:3R98|rcsb pdb:3R99|rcsb pdb:4A6Z|rcsb pdb:4A71|rcsb pdb:4A78|rcsb pdb:4A7M|rcsb pdb:4CCP|rcsb pdb:4CCX|rcsb pdb:4CVI|rcsb pdb:4CVJ|rcsb pdb:4JB4|rcsb pdb:4NFG|rcsb pdb:4P4Q|rcsb pdb:4XV4|rcsb pdb:4XV5|rcsb pdb:4XV6|rcsb pdb:4XV7|rcsb pdb:4XV8|rcsb pdb:4XVA|rcsb pdb:5CCP|rcsb pdb:5CIB|rcsb pdb:5CIC|rcsb pdb:5CID|rcsb pdb:5CIE|rcsb pdb:5CIF|rcsb pdb:5CIG|rcsb pdb:5CIH|rcsb pdb:5D6M|rcsb pdb:5EJT|rcsb pdb:5EJX|rcsb pdb:6CCP|rcsb pdb:6H08|rcsb pdb:6P41|rcsb pdb:6P42|rcsb pdb:6P43|rcsb pdb:6Y1T|rcsb pdb:6Y2Y|rcsb pdb:7CCP|sgd:YKR066C(identity)	refseq:NP_004979.3|ensembl:ENSG00000198681(gene)|ensembl:ENST00000356661(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|interpro:IPR002190(MAGE protein)|interpro:IPR021072|interpro:IPR030093|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|rcsb pdb:1W72|rcsb pdb:3BO8|dip:DIP-54794N|entrezgene/locuslink:4100(identity)	-	crc64:A5D26385DA6F0A0B	crc64:544EEB1F9F4E9D33	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:LkPXY1wuYoCFzMQPSsAtXZrRi8w559292	rogid:6XW3mnTNM3yvOtXmiFbU8Uz3hjA9606	intact-crc:F1338ECB9CEC2FA4|rigid:VQneuJ3S6d1jG8dpkHfjjzGW/0w	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96DZ9-2	uniprotkb:P00431	intact:EBI-11522780|ensembl:ENSP00000352270|ensembl:ENSP00000497215	intact:EBI-4389|uniprotkb:Q6Q5M9|uniprotkb:D6VXC7|ensemblfungi:YKR066C	psi-mi:q96dz9-2(display_long)|uniprotkb:CMTM5(gene name)|psi-mi:CMTM5(display_short)|uniprotkb:CKLFSF5(gene name synonym)|uniprotkb:Chemokine-like factor superfamily member 5(gene name synonym)	psi-mi:ccpr_yeast(display_long)|uniprotkb:CCP1(gene name)|psi-mi:CCP1(display_short)|uniprotkb:CCP(gene name synonym)|uniprotkb:CPO(gene name synonym)|uniprotkb:YKR066C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11522784|imex:IM-24995-54	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000166091(gene)|ensembl:ENST00000359320(transcript)|ensembl:ENST00000649278(transcript)|intact:EBI-2548702(isoform-parent)|uniprotkb:Q96DZ9-2(isoform-parent)|entrezgene/locuslink:116173(identity)	refseq:NP_012992.1|sgd:S000001774|dip:DIP-6251N|ensemblfungi:YKR066C(gene)|ensemblfungi:YKR066C_mRNA(transcript)|go:"GO:0000302"(response to reactive oxygen species)|go:"GO:0004130"(cytochrome-c peroxidase activity)|go:"GO:0004601"(peroxidase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0020037"(heme binding)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0046872"(metal ion binding)|interpro:IPR002016(Haem peroxidase, plant/fungal/bacterial)|interpro:IPR002207(Plant ascorbate peroxidase)|interpro:IPR010255(Haem peroxidase)|interpro:IPR019793|interpro:IPR019794|interpro:IPR044831|rcsb pdb:1A2F|rcsb pdb:1A2G|rcsb pdb:1AA4|rcsb pdb:1AC4|rcsb pdb:1AC8|rcsb pdb:1AEB|rcsb pdb:1AED|rcsb pdb:1AEE|rcsb pdb:1AEF|rcsb pdb:1AEG|rcsb pdb:1AEH|rcsb pdb:1AEJ|rcsb pdb:1AEK|rcsb pdb:1AEM|rcsb pdb:1AEN|rcsb pdb:1AEO|rcsb pdb:1AEQ|rcsb pdb:1AES|rcsb pdb:1AET|rcsb pdb:1AEU|rcsb pdb:1AEV|rcsb pdb:1BEJ|rcsb pdb:1BEK|rcsb pdb:1BEM|rcsb pdb:1BEP|rcsb pdb:1BEQ|rcsb pdb:1BES|rcsb pdb:1BJ9|rcsb pdb:1BVA|rcsb pdb:1CCA|rcsb pdb:1CCB|rcsb pdb:1CCC|rcsb pdb:1CCE|rcsb pdb:1CCG|rcsb pdb:1CCI|rcsb pdb:1CCJ|rcsb pdb:1CCK|rcsb pdb:1CCL|rcsb pdb:1CCP|rcsb pdb:1CMP|rcsb pdb:1CMQ|rcsb pdb:1CMT|rcsb pdb:1CPD|rcsb pdb:1CPE|rcsb pdb:1CPF|rcsb pdb:1CPG|rcsb pdb:1CYF|rcsb pdb:1DCC|rcsb pdb:1DJ1|rcsb pdb:1DJ5|rcsb pdb:1DS4|rcsb pdb:1DSE|rcsb pdb:1DSG|rcsb pdb:1DSO|rcsb pdb:1DSP|rcsb pdb:1EBE|rcsb pdb:1JCI|rcsb pdb:1JDR|rcsb pdb:1KOK|rcsb pdb:1KRJ|rcsb pdb:1KXM|rcsb pdb:1KXN|rcsb pdb:1MK8|rcsb pdb:1MKQ|rcsb pdb:1MKR|rcsb pdb:1ML2|rcsb pdb:1RYC|rcsb pdb:1S6V|rcsb pdb:1S73|rcsb pdb:1SBM|rcsb pdb:1SDQ|rcsb pdb:1SOG|rcsb pdb:1STQ|rcsb pdb:1U74|rcsb pdb:1U75|rcsb pdb:1Z53|rcsb pdb:1ZBY|rcsb pdb:1ZBZ|rcsb pdb:2ANZ|rcsb pdb:2AQD|rcsb pdb:2AS1|rcsb pdb:2AS2|rcsb pdb:2AS3|rcsb pdb:2AS4|rcsb pdb:2AS6|rcsb pdb:2B0Z|rcsb pdb:2B10|rcsb pdb:2B11|rcsb pdb:2B12|rcsb pdb:2BCN|rcsb pdb:2CCP|rcsb pdb:2CEP|rcsb pdb:2CYP|rcsb pdb:2EUN|rcsb pdb:2EUO|rcsb pdb:2EUP|rcsb pdb:2EUQ|rcsb pdb:2EUR|rcsb pdb:2EUS|rcsb pdb:2EUT|rcsb pdb:2EUU|rcsb pdb:2GB8|rcsb pdb:2IA8|rcsb pdb:2ICV|rcsb pdb:2JTI|rcsb pdb:2N18|rcsb pdb:2PCB|rcsb pdb:2PCC|rcsb pdb:2RBT|rcsb pdb:2RBU|rcsb pdb:2RBV|rcsb pdb:2RBW|rcsb pdb:2RBX|rcsb pdb:2RBY|rcsb pdb:2RBZ|rcsb pdb:2RC0|rcsb pdb:2RC1|rcsb pdb:2RC2|rcsb pdb:2V23|rcsb pdb:2V2E|rcsb pdb:2X07|rcsb pdb:2X08|rcsb pdb:2XIL|rcsb pdb:2XJ5|rcsb pdb:2XJ8|rcsb pdb:2Y5A|rcsb pdb:2YCG|rcsb pdb:3CCP|rcsb pdb:3CCX|rcsb pdb:3E2N|rcsb pdb:3E2O|rcsb pdb:3EXB|rcsb pdb:3M23|rcsb pdb:3M25|rcsb pdb:3M26|rcsb pdb:3M27|rcsb pdb:3M28|rcsb pdb:3M29|rcsb pdb:3M2A|rcsb pdb:1CMU|rcsb pdb:3M2B|rcsb pdb:3M2C|rcsb pdb:3M2D|rcsb pdb:3M2E|rcsb pdb:3M2F|rcsb pdb:3M2G|rcsb pdb:3M2H|rcsb pdb:3M2I|rcsb pdb:3R98|rcsb pdb:3R99|rcsb pdb:4A6Z|rcsb pdb:4A71|rcsb pdb:4A78|rcsb pdb:4A7M|rcsb pdb:4CCP|rcsb pdb:4CCX|rcsb pdb:4CVI|rcsb pdb:4CVJ|rcsb pdb:4JB4|rcsb pdb:4NFG|rcsb pdb:4P4Q|rcsb pdb:4XV4|rcsb pdb:4XV5|rcsb pdb:4XV6|rcsb pdb:4XV7|rcsb pdb:4XV8|rcsb pdb:4XVA|rcsb pdb:5CCP|rcsb pdb:5CIB|rcsb pdb:5CIC|rcsb pdb:5CID|rcsb pdb:5CIE|rcsb pdb:5CIF|rcsb pdb:5CIG|rcsb pdb:5CIH|rcsb pdb:5D6M|rcsb pdb:5EJT|rcsb pdb:5EJX|rcsb pdb:6CCP|rcsb pdb:6H08|rcsb pdb:6P41|rcsb pdb:6P42|rcsb pdb:6P43|rcsb pdb:6Y1T|rcsb pdb:6Y2Y|rcsb pdb:7CCP|sgd:YKR066C(identity)	-	-	crc64:A5D26385DA6F0A0B	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:2TJ7rZKQNb5hH5gz9i+ujOEOIOg9606	rogid:LkPXY1wuYoCFzMQPSsAtXZrRi8w559292	intact-crc:072AE829BEFCB539|rigid:/CtEOzSMFSlCAlHj1MH2wk8S2PA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P01098	uniprotkb:Q96MT8-3	intact:EBI-8080380|intact:MINT-2785764|uniprotkb:D6VRL9|ensemblfungi:YDL130W-A	intact:EBI-11522539|ensembl:ENSP00000507703|ensembl:ENSP00000328382|ensembl:ENSP00000506728|ensembl:ENSP00000506791|ensembl:ENSP00000506828|ensembl:ENSP00000507228	psi-mi:stf1_yeast(display_long)|uniprotkb:STF1(gene name)|psi-mi:STF1(display_short)|uniprotkb:AIS2(gene name synonym)|uniprotkb:ATP synthase F1 subunit epsilon(gene name synonym)|uniprotkb:YDL130BW(orf name)|uniprotkb:YDL130W-A(locus name)	psi-mi:q96mt8-3(display_long)|uniprotkb:CEP63(gene name)|psi-mi:CEP63(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11522844|imex:IM-24995-60	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010152.1|mint:P01098|interpro:IPR007648(Mitochondrial ATPase inhibitor, IATP)|sgd:S000007232|ensemblfungi:YDL130W-A_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0042030"(ATPase inhibitor activity)|go:"GO:0051117"(ATPase binding)|ensemblfungi:YDL130W-A(gene)|sgd:YDL130W-A(identity)	intact:EBI-741977(isoform-parent)|ensembl:ENST00000332047(transcript)|ensembl:ENST00000682042(transcript)|ensembl:ENST00000682800(transcript)|ensembl:ENST00000682858(transcript)|ensembl:ENST00000683177(transcript)|ensembl:ENST00000683861(transcript)|ensembl:ENSG00000182923(gene)|uniprotkb:Q96MT8-3(isoform-parent)|entrezgene/locuslink:80254(identity)	-	comment:mint|function:This is 1 of 2 proteins that can stabilize the ATPase-inhibitor complex, which normally dissociates when externally added ATP has been consumed	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:YxrqEhb1G8Ln3oLqBYbVRmFM7E4559292	rogid:U0uvVcOCzA8Qp2cCB0ilixgd4Yc9606	intact-crc:7FC7878BDA95E5AE|rigid:EPQDMBePklXPquu8Tb6djvAIJwc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9C0F1	uniprotkb:P01097	intact:EBI-744115|uniprotkb:A8K8W9|uniprotkb:B3KT53|uniprotkb:Q8IXZ4|uniprotkb:A8MW11|uniprotkb:D3DP42|ensembl:ENSP00000296519|ensembl:ENSP00000380009|ensembl:ENSP00000423153	intact:EBI-8874|ensemblfungi:YDL181W|uniprotkb:D6VRH1	psi-mi:cep44_human(display_long)|uniprotkb:HBV PreS1-transactivated protein 3(gene name synonym)|uniprotkb:CEP44(gene name)|psi-mi:CEP44(display_short)|uniprotkb:KIAA1712(gene name synonym)	psi-mi:atif_yeast(display_long)|uniprotkb:INH1(gene name)|psi-mi:INH1(display_short)|uniprotkb:ATP synthase F1 subunit epsilon(gene name synonym)|uniprotkb:D1305(orf name)|uniprotkb:YDL181W(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11522835|imex:IM-24995-59	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001035247.1|refseq:NP_001138786.1|refseq:XP_011530587.1|refseq:XP_011530588.1|refseq:XP_011530589.1|refseq:XP_016864143.1|refseq:XP_016864144.1|ensembl:ENSG00000164118(gene)|ensembl:ENST00000296519(transcript)|ensembl:ENST00000396791(transcript)|ensembl:ENST00000503780(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007099"(centriole replication)|go:"GO:0008017"(microtubule binding)|go:"GO:0010457"(centriole-centriole cohesion)|go:"GO:0030496"(midbody)|interpro:IPR029157|interpro:IPR033603|mint:Q9C0F1|entrezgene/locuslink:80817(identity)	ensemblfungi:YDL181W(gene)|ensemblfungi:YDL181W_mRNA(transcript)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0042030"(ATPase inhibitor activity)|interpro:IPR007648(Mitochondrial ATPase inhibitor, IATP)|rcsb pdb:3ZIA|refseq:NP_010100.1|sgd:S000002340|mint:P01097|dip:DIP-2985N|sgd:YDL181W(identity)	-	-	crc64:E1AF73A47F63CE58	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:gDTC64oDhudGdsssC7v+suIHZkA9606	rogid:3wsu4TOLAZdm97Kfhla8l4UKFEk559292	intact-crc:EEEF92D519E01198|rigid:p+z+1wfAmX+mwOWyhlzLBKNFvtg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P00431	uniprotkb:Q9UMX0	intact:EBI-4389|uniprotkb:Q6Q5M9|uniprotkb:D6VXC7|ensemblfungi:YKR066C	intact:EBI-741480|uniprotkb:Q8IXS9|uniprotkb:Q8N2Q3|uniprotkb:Q9H0T8|uniprotkb:Q9H3R4|uniprotkb:Q9HAZ5|intact:EBI-28967608|ensembl:ENSP00000365576|uniprotkb:Q5T6J5|uniprotkb:Q5T6J9|uniprotkb:A0A024R284	psi-mi:ccpr_yeast(display_long)|uniprotkb:CCP1(gene name)|psi-mi:CCP1(display_short)|uniprotkb:CCP(gene name synonym)|uniprotkb:CPO(gene name synonym)|uniprotkb:YKR066C(locus name)	psi-mi:ubql1_human(display_long)|uniprotkb:Protein linking IAP with cytoskeleton 1(gene name synonym)|uniprotkb:UBQLN1(gene name)|psi-mi:UBQLN1(display_short)|uniprotkb:DA41(gene name synonym)|uniprotkb:PLIC1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11522793|imex:IM-24995-55	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012992.1|sgd:S000001774|dip:DIP-6251N|ensemblfungi:YKR066C(gene)|ensemblfungi:YKR066C_mRNA(transcript)|go:"GO:0000302"(response to reactive oxygen species)|go:"GO:0004130"(cytochrome-c peroxidase activity)|go:"GO:0004601"(peroxidase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0020037"(heme binding)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0046872"(metal ion binding)|interpro:IPR002016(Haem peroxidase, plant/fungal/bacterial)|interpro:IPR002207(Plant ascorbate peroxidase)|interpro:IPR010255(Haem peroxidase)|interpro:IPR019793|interpro:IPR019794|interpro:IPR044831|rcsb pdb:1A2F|rcsb pdb:1A2G|rcsb pdb:1AA4|rcsb pdb:1AC4|rcsb pdb:1AC8|rcsb pdb:1AEB|rcsb pdb:1AED|rcsb pdb:1AEE|rcsb pdb:1AEF|rcsb pdb:1AEG|rcsb pdb:1AEH|rcsb pdb:1AEJ|rcsb pdb:1AEK|rcsb pdb:1AEM|rcsb pdb:1AEN|rcsb pdb:1AEO|rcsb pdb:1AEQ|rcsb pdb:1AES|rcsb pdb:1AET|rcsb pdb:1AEU|rcsb pdb:1AEV|rcsb pdb:1BEJ|rcsb pdb:1BEK|rcsb pdb:1BEM|rcsb pdb:1BEP|rcsb pdb:1BEQ|rcsb pdb:1BES|rcsb pdb:1BJ9|rcsb pdb:1BVA|rcsb pdb:1CCA|rcsb pdb:1CCB|rcsb pdb:1CCC|rcsb pdb:1CCE|rcsb pdb:1CCG|rcsb pdb:1CCI|rcsb pdb:1CCJ|rcsb pdb:1CCK|rcsb pdb:1CCL|rcsb pdb:1CCP|rcsb pdb:1CMP|rcsb pdb:1CMQ|rcsb pdb:1CMT|rcsb pdb:1CPD|rcsb pdb:1CPE|rcsb pdb:1CPF|rcsb pdb:1CPG|rcsb pdb:1CYF|rcsb pdb:1DCC|rcsb pdb:1DJ1|rcsb pdb:1DJ5|rcsb pdb:1DS4|rcsb pdb:1DSE|rcsb pdb:1DSG|rcsb pdb:1DSO|rcsb pdb:1DSP|rcsb pdb:1EBE|rcsb pdb:1JCI|rcsb pdb:1JDR|rcsb pdb:1KOK|rcsb pdb:1KRJ|rcsb pdb:1KXM|rcsb pdb:1KXN|rcsb pdb:1MK8|rcsb pdb:1MKQ|rcsb pdb:1MKR|rcsb pdb:1ML2|rcsb pdb:1RYC|rcsb pdb:1S6V|rcsb pdb:1S73|rcsb pdb:1SBM|rcsb pdb:1SDQ|rcsb pdb:1SOG|rcsb pdb:1STQ|rcsb pdb:1U74|rcsb pdb:1U75|rcsb pdb:1Z53|rcsb pdb:1ZBY|rcsb pdb:1ZBZ|rcsb pdb:2ANZ|rcsb pdb:2AQD|rcsb pdb:2AS1|rcsb pdb:2AS2|rcsb pdb:2AS3|rcsb pdb:2AS4|rcsb pdb:2AS6|rcsb pdb:2B0Z|rcsb pdb:2B10|rcsb pdb:2B11|rcsb pdb:2B12|rcsb pdb:2BCN|rcsb pdb:2CCP|rcsb pdb:2CEP|rcsb pdb:2CYP|rcsb pdb:2EUN|rcsb pdb:2EUO|rcsb pdb:2EUP|rcsb pdb:2EUQ|rcsb pdb:2EUR|rcsb pdb:2EUS|rcsb pdb:2EUT|rcsb pdb:2EUU|rcsb pdb:2GB8|rcsb pdb:2IA8|rcsb pdb:2ICV|rcsb pdb:2JTI|rcsb pdb:2N18|rcsb pdb:2PCB|rcsb pdb:2PCC|rcsb pdb:2RBT|rcsb pdb:2RBU|rcsb pdb:2RBV|rcsb pdb:2RBW|rcsb pdb:2RBX|rcsb pdb:2RBY|rcsb pdb:2RBZ|rcsb pdb:2RC0|rcsb pdb:2RC1|rcsb pdb:2RC2|rcsb pdb:2V23|rcsb pdb:2V2E|rcsb pdb:2X07|rcsb pdb:2X08|rcsb pdb:2XIL|rcsb pdb:2XJ5|rcsb pdb:2XJ8|rcsb pdb:2Y5A|rcsb pdb:2YCG|rcsb pdb:3CCP|rcsb pdb:3CCX|rcsb pdb:3E2N|rcsb pdb:3E2O|rcsb pdb:3EXB|rcsb pdb:3M23|rcsb pdb:3M25|rcsb pdb:3M26|rcsb pdb:3M27|rcsb pdb:3M28|rcsb pdb:3M29|rcsb pdb:3M2A|rcsb pdb:1CMU|rcsb pdb:3M2B|rcsb pdb:3M2C|rcsb pdb:3M2D|rcsb pdb:3M2E|rcsb pdb:3M2F|rcsb pdb:3M2G|rcsb pdb:3M2H|rcsb pdb:3M2I|rcsb pdb:3R98|rcsb pdb:3R99|rcsb pdb:4A6Z|rcsb pdb:4A71|rcsb pdb:4A78|rcsb pdb:4A7M|rcsb pdb:4CCP|rcsb pdb:4CCX|rcsb pdb:4CVI|rcsb pdb:4CVJ|rcsb pdb:4JB4|rcsb pdb:4NFG|rcsb pdb:4P4Q|rcsb pdb:4XV4|rcsb pdb:4XV5|rcsb pdb:4XV6|rcsb pdb:4XV7|rcsb pdb:4XV8|rcsb pdb:4XVA|rcsb pdb:5CCP|rcsb pdb:5CIB|rcsb pdb:5CIC|rcsb pdb:5CID|rcsb pdb:5CIE|rcsb pdb:5CIF|rcsb pdb:5CIG|rcsb pdb:5CIH|rcsb pdb:5D6M|rcsb pdb:5EJT|rcsb pdb:5EJX|rcsb pdb:6CCP|rcsb pdb:6H08|rcsb pdb:6P41|rcsb pdb:6P42|rcsb pdb:6P43|rcsb pdb:6Y1T|rcsb pdb:6Y2Y|rcsb pdb:7CCP|sgd:YKR066C(identity)	ensembl:ENST00000257468|ensembl:ENSP00000257468|ensembl:ENSP00000365576|ensembl:ENSG00000135018(gene)|ensembl:ENST00000376395(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000502"(proteasome complex)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016235"(aggresome)|go:"GO:0016236"(macroautophagy)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0019900"(kinase binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035973"(aggrephagy)|go:"GO:0042802"(identical protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0097352"(autophagosome maturation)|go:"GO:1901340"(negative regulation of store-operated calcium channel activity)|go:"GO:1902175"(regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)|interpro:IPR000626(Ubiquitin)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR028430|interpro:IPR029071|mint:Q9UMX0|rcsb pdb:2JY5|rcsb pdb:2JY6|rcsb pdb:2KLC|reactome:R-HSA-8856825|refseq:NP_038466.2|refseq:NP_444295.1|dip:DIP-41629N|entrezgene/locuslink:29979(identity)	-	crc64:A5D26385DA6F0A0B	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:LkPXY1wuYoCFzMQPSsAtXZrRi8w559292	rogid:nCFfZbGCTvRYaXhQ4R99XblslvM9606	intact-crc:67906DC832714B8E|rigid:g40l7JFLNqTJJNp+yGPGLvMZdY4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8IUQ4-2	uniprotkb:P01097	intact:EBI-11522811|ensembl:ENSP00000349156	intact:EBI-8874|ensemblfungi:YDL181W|uniprotkb:D6VRH1	psi-mi:q8iuq4-2(display_long)|uniprotkb:SIAH1(gene name)|psi-mi:SIAH1(display_short)|uniprotkb:HUMSIAH(gene name synonym)|uniprotkb:Seven in absentia homolog 1(gene name synonym)|uniprotkb:Siah-1a(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase SIAH1(gene name synonym)	psi-mi:atif_yeast(display_long)|uniprotkb:INH1(gene name)|psi-mi:INH1(display_short)|uniprotkb:ATP synthase F1 subunit epsilon(gene name synonym)|uniprotkb:D1305(orf name)|uniprotkb:YDL181W(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11522815|imex:IM-24995-57	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-747107(isoform-parent)|ensembl:ENSG00000196470(gene)|ensembl:ENST00000356721(transcript)|uniprotkb:Q8IUQ4-2(isoform-parent)|entrezgene/locuslink:6477(identity)	ensemblfungi:YDL181W(gene)|ensemblfungi:YDL181W_mRNA(transcript)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0042030"(ATPase inhibitor activity)|interpro:IPR007648(Mitochondrial ATPase inhibitor, IATP)|rcsb pdb:3ZIA|refseq:NP_010100.1|sgd:S000002340|mint:P01097|dip:DIP-2985N|sgd:YDL181W(identity)	-	-	crc64:E1AF73A47F63CE58	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:M4q06jVbWuq1mGMXvtuFBaMEgZM9606	rogid:3wsu4TOLAZdm97Kfhla8l4UKFEk559292	intact-crc:AA9910113485F41D|rigid:lxgj5yAVRLdMImSQ2jj9qkoEhcI	false	sufficient binding region:32-313	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O43765	uniprotkb:P00724	intact:EBI-347996|ensembl:ENSP00000221566|ensembl:ENSP00000503397|ensembl:ENSP00000504495|uniprotkb:Q9BTZ9|intact:EBI-1045243|uniprotkb:Q6FIA9|uniprotkb:D6W610	intact:EBI-9282|ensemblfungi:YIL162W|uniprotkb:Q12671|uniprotkb:D6VVC4	psi-mi:sgta_human(display_long)|uniprotkb:SGTA(gene name)|psi-mi:SGTA(display_short)|uniprotkb:SGT(gene name synonym)|uniprotkb:Alpha-SGT(gene name synonym)|uniprotkb:Vpu-binding protein(gene name synonym)|uniprotkb:SGT1(gene name synonym)	psi-mi:inv2_yeast(display_long)|uniprotkb:SUC2(gene name)|psi-mi:SUC2(display_short)|uniprotkb:YIL162W(locus name)|uniprotkb:Beta-fructofuranosidase 2(gene name synonym)|uniprotkb:Saccharase(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11522802|imex:IM-24995-56	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:4CPG|rcsb pdb:4GOD|rcsb pdb:4GOE|rcsb pdb:4GOF|reactome:R-HSA-9609523|rcsb pdb:2VYI|ensembl:ENSG00000104969(gene)|ensembl:ENST00000221566(transcript)|ensembl:ENST00000676943(transcript)|ensembl:ENST00000677149(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072380"(TRC complex)|go:"GO:0098850"(extrinsic component of synaptic vesicle membrane)|go:"GO:1903070"(negative regulation of ER-associated ubiquitin-dependent protein catabolic process)|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)|go:"GO:1903646"(positive regulation of chaperone-mediated protein folding)|go:"GO:1904288"(BAT3 complex binding)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR032374|mint:O43765|refseq:XP_011526480.1|refseq:NP_003012.1|entrezgene/locuslink:6449(identity)	ensemblfungi:YIL162W(gene)|ensemblfungi:YIL162W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0004564"(beta-fructofuranosidase activity)|go:"GO:0004575"(sucrose alpha-glucosidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005987"(sucrose catabolic process)|go:"GO:0010147"(fructan catabolic process)|go:"GO:0034484"(raffinose catabolic process)|go:"GO:0051670"(inulinase activity)|go:"GO:0071944"(cell periphery)|go:"GO:1902927"(inulin catabolic process)|interpro:IPR001362(Glycoside hydrolase, family 32)|interpro:IPR013148(Glycosyl hydrolases family 32, N-terminal)|interpro:IPR013189(Glycosyl hydrolase family 32, C-terminal)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR018053|interpro:IPR023296|rcsb pdb:4EQV|refseq:NP_012104.1|sgd:S000001424|dip:DIP-5542N|mint:P00724|sgd:YIL162W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:r/Cyj4UJk/cS8QdrbjhTZMPCigI9606	rogid:I6j4m4s8gvTdurEXs3Q7hTrpO30559292	intact-crc:7DB0BF57D2016233|rigid:v2A+BV0dFY1i3+2cxNb0J5rI+DE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P01097	uniprotkb:Q96MT8-3	intact:EBI-8874|ensemblfungi:YDL181W|uniprotkb:D6VRH1	intact:EBI-11522539|ensembl:ENSP00000507703|ensembl:ENSP00000328382|ensembl:ENSP00000506728|ensembl:ENSP00000506791|ensembl:ENSP00000506828|ensembl:ENSP00000507228	psi-mi:atif_yeast(display_long)|uniprotkb:INH1(gene name)|psi-mi:INH1(display_short)|uniprotkb:ATP synthase F1 subunit epsilon(gene name synonym)|uniprotkb:D1305(orf name)|uniprotkb:YDL181W(locus name)	psi-mi:q96mt8-3(display_long)|uniprotkb:CEP63(gene name)|psi-mi:CEP63(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11522826|imex:IM-24995-58	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YDL181W(gene)|ensemblfungi:YDL181W_mRNA(transcript)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0042030"(ATPase inhibitor activity)|interpro:IPR007648(Mitochondrial ATPase inhibitor, IATP)|rcsb pdb:3ZIA|refseq:NP_010100.1|sgd:S000002340|mint:P01097|dip:DIP-2985N|sgd:YDL181W(identity)	intact:EBI-741977(isoform-parent)|ensembl:ENST00000332047(transcript)|ensembl:ENST00000682042(transcript)|ensembl:ENST00000682800(transcript)|ensembl:ENST00000682858(transcript)|ensembl:ENST00000683177(transcript)|ensembl:ENST00000683861(transcript)|ensembl:ENSG00000182923(gene)|uniprotkb:Q96MT8-3(isoform-parent)|entrezgene/locuslink:80254(identity)	-	crc64:E1AF73A47F63CE58	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:3wsu4TOLAZdm97Kfhla8l4UKFEk559292	rogid:U0uvVcOCzA8Qp2cCB0ilixgd4Yc9606	intact-crc:3AFC4F678E929BA6|rigid:5ZYraKRCqZFQ5aHI1Bh7OK50qkY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P01123	uniprotkb:Q96CV9	intact:EBI-29496|uniprotkb:D6VTJ2|ensemblfungi:YFL038C	intact:EBI-748974|uniprotkb:Q5T672|uniprotkb:Q5T673|uniprotkb:Q5T674|uniprotkb:Q5T675|uniprotkb:Q7LDL9|uniprotkb:Q8N562|uniprotkb:Q9UET9|uniprotkb:Q9UEV4|uniprotkb:Q9Y218|uniprotkb:B3KP00|uniprotkb:D3DRS4|uniprotkb:D3DRS8|ensembl:ENSP00000263036|ensembl:ENSP00000368021|ensembl:ENSP00000368022|ensembl:ENSP00000368032	psi-mi:ypt1_yeast(display_long)|uniprotkb:YFL038C(locus name)|uniprotkb:YPT1(gene name)|psi-mi:YPT1(display_short)|uniprotkb:YP2(gene name synonym)|uniprotkb:Rab GTPase YPT1(gene name synonym)|uniprotkb:Transport GTPase YPT1(gene name synonym)|uniprotkb:Protein YP2(gene name synonym)	psi-mi:optn_human(display_long)|uniprotkb:HYPL(gene name synonym)|uniprotkb:Optic neuropathy-inducing protein(gene name synonym)|uniprotkb:E3-14.7K-interacting protein(gene name synonym)|uniprotkb:FIP-2(gene name synonym)|uniprotkb:Huntingtin-interacting protein L(gene name synonym)|uniprotkb:Huntingtin yeast partner L(gene name synonym)|uniprotkb:NEMO-related protein(gene name synonym)|uniprotkb:Transcription factor IIIA-interacting protein(gene name synonym)|uniprotkb:OPTN(gene name)|psi-mi:OPTN(display_short)|uniprotkb:FIP2(gene name synonym)|uniprotkb:GLC1E(gene name synonym)|uniprotkb:NRP(gene name synonym)|uniprotkb:HIP7(gene name synonym)|uniprotkb:Huntingtin-interacting protein 7(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11522853|imex:IM-24995-61	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_116615.1|sgd:S000001856|dip:DIP-2019N|mint:P01123|ensemblfungi:YFL038C(gene)|ensemblfungi:YFL038C_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005795"(Golgi stack)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0012505"(endomembrane system)|go:"GO:0016236"(macroautophagy)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0032456"(endocytic recycling)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0034498"(early endosome to Golgi transport)|go:"GO:0035493"(SNARE complex assembly)|go:"GO:0035494"(SNARE complex disassembly)|go:"GO:0043549"(regulation of kinase activity)|go:"GO:0048194"(Golgi vesicle budding)|go:"GO:0048211"(Golgi vesicle docking)|go:"GO:0061709"(reticulophagy)|go:"GO:0090114"(COPII-coated vesicle budding)|go:"GO:1900101"(regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1990261"(pre-mRNA catabolic process)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|rcsb pdb:1UKV|rcsb pdb:1YZN|rcsb pdb:2BCG|rcsb pdb:3CUE|rcsb pdb:7KMT|reactome:R-SCE-162658|reactome:R-SCE-204005|reactome:R-SCE-6807878|reactome:R-SCE-6811434|reactome:R-SCE-8873719|reactome:R-SCE-8876198|sgd:YFL038C(identity)	refseq:NP_001008212.1|refseq:NP_001008213.1|refseq:NP_001008214.1|refseq:NP_068815.2|ensembl:ENSG00000123240(gene)|ensembl:ENST00000263036(transcript)|ensembl:ENST00000378747(transcript)|ensembl:ENST00000378748(transcript)|ensembl:ENST00000378757(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001920"(negative regulation of receptor recycling)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0007030"(Golgi organization)|go:"GO:0007165"(signal transduction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008219"(cell death)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0061734"(parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:1904417"(positive regulation of xenophagy)|interpro:IPR021063|interpro:IPR032419|interpro:IPR032939|interpro:IPR034735|mint:Q96CV9|rcsb pdb:2LO4|rcsb pdb:2LUE|rcsb pdb:3VTV|rcsb pdb:3VTW|rcsb pdb:5AAZ|rcsb pdb:5B83|rcsb pdb:5EOA|rcsb pdb:5EOF|rcsb pdb:7CZM|reactome:R-HSA-2565942|reactome:R-HSA-8854214|dip:DIP-42001N|entrezgene/locuslink:10133(identity)	-	crc64:F8C704F6BF2D227B	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2018/04/06	rogid:IMz/iERXs1zvX+wgJ9x7Uk0ovQ8559292	rogid:jcCTXDx1bJq3K5mgNUD73jeWeBU9606	intact-crc:2CCD1C86AAF328DE|rigid:XU2Ln8eZWI9Gyv83WsGcWnDzStU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96BA8	uniprotkb:P05375	intact:EBI-6942903|ensembl:ENSP00000481956|intact:MINT-268046|intact:MINT-8162577|uniprotkb:Q8N2D5|uniprotkb:Q96CP0	intact:EBI-13119|uniprotkb:D6VWP3|ensemblfungi:YJR073C	psi-mi:cr3l1_human(display_long)|uniprotkb:CREB3L1(gene name)|psi-mi:CREB3L1(display_short)|uniprotkb:OASIS(gene name synonym)|uniprotkb:PSEC0238(orf name)|uniprotkb:Old astrocyte specifically-induced substance(gene name synonym)	psi-mi:plmt_yeast(display_long)|uniprotkb:OPI3(gene name)|psi-mi:OPI3(display_short)|uniprotkb:PEM2(gene name synonym)|uniprotkb:Overproducer of inositol protein 3(gene name synonym)|uniprotkb:Phospholipid methyltransferase(gene name synonym)|uniprotkb:J1824(orf name)|uniprotkb:YJR073C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11522916|imex:IM-24995-68	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157613(gene)|ensembl:ENST00000621158(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0070278"(extracellular matrix constituent secretion)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029805|mint:Q96BA8|reactome:R-HSA-8874211|refseq:NP_443086.1|entrezgene/locuslink:90993(identity)	refseq:NP_012607.1|sgd:S000003834|reactome:R-SCE-1483191|dip:DIP-2888N|ensemblfungi:YJR073C(gene)|ensemblfungi:YJR073C_mRNA(transcript)|go:"GO:0000773"(phosphatidyl-N-methylethanolamine N-methyltransferase activity)|go:"GO:0004608"(phosphatidylethanolamine N-methyltransferase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006656"(phosphatidylcholine biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032259"(methylation)|go:"GO:0071944"(cell periphery)|go:"GO:0080101"(phosphatidyl-N-dimethylethanolamine N-methyltransferase activity)|interpro:IPR007318(Phospholipid methyltransferase)|interpro:IPR024960|sgd:YJR073C(identity)	-	comment:mint|function:"Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE"	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:sMWUFmBeBBCO+T0Y2CuB/un1lBg9606	rogid:5jLJ+pCvOmgw3FFJDmZ5HOwI+BI559292	intact-crc:3072B80CFC822437|rigid:mak0qGTKwIm2BLg50IeXlVkEyiA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96DZ9-2	uniprotkb:P04819	intact:EBI-11522780|ensembl:ENSP00000352270|ensembl:ENSP00000497215	intact:EBI-5991|uniprotkb:Q12736|uniprotkb:D6VRI7|ensemblfungi:YDL164C	psi-mi:q96dz9-2(display_long)|uniprotkb:CMTM5(gene name)|psi-mi:CMTM5(display_short)|uniprotkb:CKLFSF5(gene name synonym)|uniprotkb:Chemokine-like factor superfamily member 5(gene name synonym)	psi-mi:dnli1_yeast(display_long)|uniprotkb:YDL164C(locus name)|uniprotkb:CDC9(gene name)|psi-mi:CDC9(display_short)|uniprotkb:DNA ligase I(gene name synonym)|uniprotkb:Polydeoxyribonucleotide synthase [ATP] 1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11522907|imex:IM-24995-67	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000166091(gene)|ensembl:ENST00000359320(transcript)|ensembl:ENST00000649278(transcript)|intact:EBI-2548702(isoform-parent)|uniprotkb:Q96DZ9-2(isoform-parent)|entrezgene/locuslink:116173(identity)	refseq:NP_010117.1|sgd:S000002323|dip:DIP-5630N|mint:P04819|ensemblfungi:YDL164C(gene)|ensemblfungi:YDL164C_mRNA(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003677"(DNA binding)|go:"GO:0003910"("DNA ligase (ATP) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006266"(DNA ligation)|go:"GO:0006273"(lagging strand elongation)|go:"GO:0006284"(base-excision repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0035753"(maintenance of DNA trinucleotide repeats)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:0071897"(DNA biosynthetic process)|go:"GO:1903461"(Okazaki fragment processing involved in mitotic DNA replication)|interpro:IPR000977(ATP-dependent DNA ligase)|interpro:IPR012308(DNA ligase, N-terminal)|interpro:IPR012309(ATP dependent DNA ligase, C-terminal)|interpro:IPR012310(ATP dependent DNA ligase, central)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR016059(ATP-dependent DNA ligase, conserved site)|interpro:IPR036599|rcsb pdb:2OD8|reactome:R-SCE-5358565|reactome:R-SCE-5358606|reactome:R-SCE-6782210|reactome:R-SCE-69183|sgd:YDL164C(identity)	-	-	crc64:B7C2ECAF5C61CAE7	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:2TJ7rZKQNb5hH5gz9i+ujOEOIOg9606	rogid:sl00ubCmkTFwW2bznucqEF60I3M559292	intact-crc:2433F73BE5C54E32|rigid:3eAaeCLoVTYQ+m29PX6da1v9rFg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96CV9-2	uniprotkb:P01123	intact:EBI-9091423|ensembl:ENSP00000368027|ensembl:ENSP00000368040	intact:EBI-29496|uniprotkb:D6VTJ2|ensemblfungi:YFL038C	psi-mi:q96cv9-2(display_long)|uniprotkb:E3-14.7K-interacting protein(gene name synonym)|uniprotkb:FIP-2(gene name synonym)|uniprotkb:FIP2(gene name synonym)|uniprotkb:GLC1E(gene name synonym)|uniprotkb:HIP7(gene name synonym)|uniprotkb:HYPL(gene name synonym)|uniprotkb:Huntingtin yeast partner L(gene name synonym)|uniprotkb:Huntingtin-interacting protein 7(gene name synonym)|uniprotkb:Huntingtin-interacting protein L(gene name synonym)|uniprotkb:NEMO-related protein(gene name synonym)|uniprotkb:NRP(gene name synonym)|uniprotkb:Optic neuropathy-inducing protein(gene name synonym)|uniprotkb:Transcription factor IIIA-interacting protein(gene name synonym)|uniprotkb:OPTN(gene name)|psi-mi:OPTN(display_short)	psi-mi:ypt1_yeast(display_long)|uniprotkb:YFL038C(locus name)|uniprotkb:YPT1(gene name)|psi-mi:YPT1(display_short)|uniprotkb:YP2(gene name synonym)|uniprotkb:Rab GTPase YPT1(gene name synonym)|uniprotkb:Transport GTPase YPT1(gene name synonym)|uniprotkb:Protein YP2(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11522862|imex:IM-24995-62	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-748974(isoform-parent)|ensembl:ENST00000378752(transcript)|ensembl:ENST00000378764(transcript)|ensembl:ENSG00000123240(gene)|uniprotkb:Q96CV9-2(isoform-parent)|entrezgene/locuslink:10133(identity)	refseq:NP_116615.1|sgd:S000001856|dip:DIP-2019N|mint:P01123|ensemblfungi:YFL038C(gene)|ensemblfungi:YFL038C_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005795"(Golgi stack)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0012505"(endomembrane system)|go:"GO:0016236"(macroautophagy)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0032456"(endocytic recycling)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0034498"(early endosome to Golgi transport)|go:"GO:0035493"(SNARE complex assembly)|go:"GO:0035494"(SNARE complex disassembly)|go:"GO:0043549"(regulation of kinase activity)|go:"GO:0048194"(Golgi vesicle budding)|go:"GO:0048211"(Golgi vesicle docking)|go:"GO:0061709"(reticulophagy)|go:"GO:0090114"(COPII-coated vesicle budding)|go:"GO:1900101"(regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1990261"(pre-mRNA catabolic process)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|rcsb pdb:1UKV|rcsb pdb:1YZN|rcsb pdb:2BCG|rcsb pdb:3CUE|rcsb pdb:7KMT|reactome:R-SCE-162658|reactome:R-SCE-204005|reactome:R-SCE-6807878|reactome:R-SCE-6811434|reactome:R-SCE-8873719|reactome:R-SCE-8876198|sgd:YFL038C(identity)	-	isoform-comment:No experimental confirmation available.	crc64:F8C704F6BF2D227B	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2018/04/06	rogid:ygzEQkiDJwDAMUuFQuOWsSIqwAk9606	rogid:IMz/iERXs1zvX+wgJ9x7Uk0ovQ8559292	intact-crc:A959F6F5715845AD|rigid:iKF4Z+I6+j8IuUp9FYB7VvlHFgw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q6RW13-2	uniprotkb:P04819	intact:EBI-11522760|ensembl:ENSP00000365816	intact:EBI-5991|uniprotkb:Q12736|uniprotkb:D6VRI7|ensemblfungi:YDL164C	psi-mi:q6rw13-2(display_long)|uniprotkb:AGTRAP(gene name)|psi-mi:AGTRAP(display_short)|uniprotkb:AT1 receptor-associated protein(gene name synonym)|uniprotkb:ATRAP(gene name synonym)	psi-mi:dnli1_yeast(display_long)|uniprotkb:YDL164C(locus name)|uniprotkb:CDC9(gene name)|psi-mi:CDC9(display_short)|uniprotkb:DNA ligase I(gene name synonym)|uniprotkb:Polydeoxyribonucleotide synthase [ATP] 1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11522889|imex:IM-24995-65	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000177674(gene)|ensembl:ENST00000376629(transcript)|intact:EBI-741181(isoform-parent)|uniprotkb:Q6RW13-2(isoform-parent)|entrezgene/locuslink:57085(identity)	refseq:NP_010117.1|sgd:S000002323|dip:DIP-5630N|mint:P04819|ensemblfungi:YDL164C(gene)|ensemblfungi:YDL164C_mRNA(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003677"(DNA binding)|go:"GO:0003910"("DNA ligase (ATP) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006266"(DNA ligation)|go:"GO:0006273"(lagging strand elongation)|go:"GO:0006284"(base-excision repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0035753"(maintenance of DNA trinucleotide repeats)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:0071897"(DNA biosynthetic process)|go:"GO:1903461"(Okazaki fragment processing involved in mitotic DNA replication)|interpro:IPR000977(ATP-dependent DNA ligase)|interpro:IPR012308(DNA ligase, N-terminal)|interpro:IPR012309(ATP dependent DNA ligase, C-terminal)|interpro:IPR012310(ATP dependent DNA ligase, central)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR016059(ATP-dependent DNA ligase, conserved site)|interpro:IPR036599|rcsb pdb:2OD8|reactome:R-SCE-5358565|reactome:R-SCE-5358606|reactome:R-SCE-6782210|reactome:R-SCE-69183|sgd:YDL164C(identity)	-	-	crc64:B7C2ECAF5C61CAE7	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:PNzVis/8puQZBJ562gCqZKc078s9606	rogid:sl00ubCmkTFwW2bznucqEF60I3M559292	intact-crc:022042515527870D|rigid:BQ0xwnjpl3+ZguuTGK0dY4JVs44	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P04819	uniprotkb:Q15041	intact:EBI-5991|uniprotkb:Q12736|uniprotkb:D6VRI7|ensemblfungi:YDL164C	intact:EBI-714543|ensembl:ENSP00000306788|uniprotkb:B7Z6S5|uniprotkb:B7Z791|uniprotkb:F5GXP4	psi-mi:dnli1_yeast(display_long)|uniprotkb:YDL164C(locus name)|uniprotkb:CDC9(gene name)|psi-mi:CDC9(display_short)|uniprotkb:DNA ligase I(gene name synonym)|uniprotkb:Polydeoxyribonucleotide synthase [ATP] 1(gene name synonym)	psi-mi:ar6p1_human(display_long)|uniprotkb:ARL6IP(gene name synonym)|uniprotkb:ARL6IP1(gene name)|psi-mi:ARL6IP1(display_short)|uniprotkb:KIAA0069(gene name synonym)|uniprotkb:ARMER(gene name synonym)|uniprotkb:Apoptotic regulator in the membrane of the endoplasmic reticulum(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11522880|imex:IM-24995-64	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010117.1|sgd:S000002323|dip:DIP-5630N|mint:P04819|ensemblfungi:YDL164C(gene)|ensemblfungi:YDL164C_mRNA(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003677"(DNA binding)|go:"GO:0003910"("DNA ligase (ATP) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006266"(DNA ligation)|go:"GO:0006273"(lagging strand elongation)|go:"GO:0006284"(base-excision repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0035753"(maintenance of DNA trinucleotide repeats)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:0071897"(DNA biosynthetic process)|go:"GO:1903461"(Okazaki fragment processing involved in mitotic DNA replication)|interpro:IPR000977(ATP-dependent DNA ligase)|interpro:IPR012308(DNA ligase, N-terminal)|interpro:IPR012309(ATP dependent DNA ligase, C-terminal)|interpro:IPR012310(ATP dependent DNA ligase, central)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR016059(ATP-dependent DNA ligase, conserved site)|interpro:IPR036599|rcsb pdb:2OD8|reactome:R-SCE-5358565|reactome:R-SCE-5358606|reactome:R-SCE-6782210|reactome:R-SCE-69183|sgd:YDL164C(identity)	refseq:NP_055976.1|ensembl:ENSG00000170540(gene)|ensembl:ENST00000304414(transcript)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006613"(cotranslational protein targeting to membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0071787"(endoplasmic reticulum tubular network formation)|go:"GO:1903371"(regulation of endoplasmic reticulum tubular network organization)|go:"GO:1990809"(endoplasmic reticulum tubular network membrane organization)|interpro:IPR033301|mint:Q15041|go:"GO:0002038"(positive regulation of L-glutamate import across plasma membrane)|refseq:NP_001300787.1|entrezgene/locuslink:23204(identity)	-	crc64:B7C2ECAF5C61CAE7	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:sl00ubCmkTFwW2bznucqEF60I3M559292	rogid:3fjkoyvUx25po7xsPcXgpjEeLJg9606	intact-crc:F9DCC4FDEA7F769C|rigid:ERVbPUWiIjvEJNHRtyq/VzxEWUk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P63279	uniprotkb:P04046	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	intact:EBI-14238|ensemblfungi:YMR300C|uniprotkb:D6W0C7	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:pur1_yeast(display_long)|uniprotkb:Glutamine phosphoribosylpyrophosphate amidotransferase(gene name synonym)|uniprotkb:ADE4(gene name)|psi-mi:ADE4(display_short)|uniprotkb:YMR300C(locus name)|uniprotkb:YM9952.02C(orf name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11522871|imex:IM-24995-63	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N|entrezgene/locuslink:7329(identity)	refseq:NP_014029.1|sgd:S000004915|ensemblfungi:YMR300C(gene)|go:"GO:0009116"(nucleoside metabolic process)|go:"GO:0046872"(metal ion binding)|interpro:IPR000836(Phosphoribosyltransferase)|interpro:IPR005854(Amidophosphoribosyl transferase)|ensemblfungi:YMR300C_mRNA(transcript)|go:"GO:0004044"(amidophosphoribosyltransferase activity)|go:"GO:0005737"(cytoplasm)|interpro:IPR017932|interpro:IPR029055|interpro:IPR029057|interpro:IPR035584|go:"GO:0006164"(purine nucleotide biosynthetic process)|go:"GO:0006189"('de novo' IMP biosynthetic process)|go:"GO:0006541"(glutamine metabolic process)|go:"GO:0009113"(purine nucleobase biosynthetic process)|mint:P04046|dip:DIP-6727N|sgd:YMR300C(identity)	-	-	crc64:1FE7A6F5B7C96710	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	rogid:v3Q2NjIC4OuMxGAFnC+1r4y70mw559292	intact-crc:9035F0832A97B023|rigid:emC0gnGMB34N9GN/LUQPL3YvnPk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q969L2	uniprotkb:P04819	intact:EBI-944295|uniprotkb:Q6ZMD9|uniprotkb:B2R520|ensembl:ENSP00000479708	intact:EBI-5991|uniprotkb:Q12736|uniprotkb:D6VRI7|ensemblfungi:YDL164C	psi-mi:mal2_human(display_long)|uniprotkb:MAL2(gene name)|psi-mi:MAL2(display_short)	psi-mi:dnli1_yeast(display_long)|uniprotkb:YDL164C(locus name)|uniprotkb:CDC9(gene name)|psi-mi:CDC9(display_short)|uniprotkb:DNA ligase I(gene name synonym)|uniprotkb:Polydeoxyribonucleotide synthase [ATP] 1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11522898|imex:IM-24995-66	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_443118.1|ensembl:ENSG00000147676(gene)|ensembl:ENST00000614891(transcript)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019911"(structural constituent of myelin sheath)|go:"GO:0042552"(myelination)|go:"GO:0045056"(transcytosis)|go:"GO:0045121"(membrane raft)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|interpro:IPR008253(Marvel)|interpro:IPR013295("Myelin and lymphocyte (MAL)")|interpro:IPR033240|entrezgene/locuslink:114569(identity)	refseq:NP_010117.1|sgd:S000002323|dip:DIP-5630N|mint:P04819|ensemblfungi:YDL164C(gene)|ensemblfungi:YDL164C_mRNA(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003677"(DNA binding)|go:"GO:0003910"("DNA ligase (ATP) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006266"(DNA ligation)|go:"GO:0006273"(lagging strand elongation)|go:"GO:0006284"(base-excision repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0035753"(maintenance of DNA trinucleotide repeats)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:0071897"(DNA biosynthetic process)|go:"GO:1903461"(Okazaki fragment processing involved in mitotic DNA replication)|interpro:IPR000977(ATP-dependent DNA ligase)|interpro:IPR012308(DNA ligase, N-terminal)|interpro:IPR012309(ATP dependent DNA ligase, C-terminal)|interpro:IPR012310(ATP dependent DNA ligase, central)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR016059(ATP-dependent DNA ligase, conserved site)|interpro:IPR036599|rcsb pdb:2OD8|reactome:R-SCE-5358565|reactome:R-SCE-5358606|reactome:R-SCE-6782210|reactome:R-SCE-69183|sgd:YDL164C(identity)	-	-	crc64:B7C2ECAF5C61CAE7	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:7SApzrGTzj8V3GIwkdO0X/z6geg9606	rogid:sl00ubCmkTFwW2bznucqEF60I3M559292	intact-crc:828316775089FF96|rigid:/Drab1hR2vpQO5x3xAkCFelwpTQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P50222	uniprotkb:P06782	intact:EBI-748397|uniprotkb:O75263|ensembl:ENSP00000262041|uniprotkb:Q9UPL6|uniprotkb:B2R8I7|intact:EBI-10172134|intact:EBI-11522964|intact:EBI-11750003|intact:EBI-12702266|uniprotkb:A4D127	intact:EBI-17516|uniprotkb:D6VTA0|ensemblfungi:YDR477W	psi-mi:meox2_human(display_long)|uniprotkb:Mesenchyme homeobox 2(gene name synonym)|uniprotkb:Growth arrest-specific homeobox(gene name synonym)|uniprotkb:MEOX2(gene name)|psi-mi:MEOX2(display_short)|uniprotkb:GAX(gene name synonym)|uniprotkb:MOX2(gene name synonym)	psi-mi:snf1_yeast(display_long)|uniprotkb:SNF1(gene name)|psi-mi:SNF1(display_short)|uniprotkb:CAT1(gene name synonym)|uniprotkb:CCR1(gene name synonym)|uniprotkb:GLC2(gene name synonym)|uniprotkb:PAS14(gene name synonym)|uniprotkb:Sucrose nonfermentating protein 1(gene name synonym)|uniprotkb:D8035.20(orf name)|uniprotkb:YDR477W(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11522962|imex:IM-24995-73	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000106511(gene)|ensembl:ENST00000262041(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0001757"(somite specification)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007275"(multicellular organism development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008015"(blood circulation)|go:"GO:0016607"(nuclear speck)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060173"(limb development)|go:"GO:0061053"(somite development)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR042634|refseq:NP_005915.2|entrezgene/locuslink:4223(identity)	refseq:NP_010765.3|sgd:S000002885|ensemblfungi:YDR477W(gene)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0071940"(fungal-type cell wall assembly)|go:"GO:0090606"(single-species surface biofilm formation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900436"(positive regulation of filamentous growth of a population of unicellular organisms in response to starvation)|go:"GO:2000222"(positive regulation of pseudohyphal growth)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013896(Ubiquitin-associated region 2)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR028375|interpro:IPR032270|rcsb pdb:2FH9|rcsb pdb:2QLV|rcsb pdb:3DAE|rcsb pdb:3HYH|rcsb pdb:3MN3|rcsb pdb:3T4N|rcsb pdb:3TDH|rcsb pdb:3TE5|reactome:R-SCE-1632852|reactome:R-SCE-163680|reactome:R-SCE-200425|reactome:R-SCE-380972|ensemblfungi:YDR477W_mRNA(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000144"(cellular bud neck septin ring)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004679"(AMP-activated protein kinase activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005641"(nuclear envelope lumen)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0007155"(cell adhesion)|go:"GO:0016239"(positive regulation of macroautophagy)|dip:DIP-18N|mint:P06782|sgd:YDR477W(identity)	-	-	crc64:F5C63565C986C4E3	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2017/05/26	rogid:fMv0ruKikzQ3MC0PBvJ3pOAjW+U9606	rogid:O/SAW1kJE3fpoXPHGLG01i9RePs559292	intact-crc:B606443E7D79CE4C|rigid:PszU6JY+588CpoIjGSz9UPjgW0o	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8N6L0	uniprotkb:P06197	intact:EBI-749265|uniprotkb:Q96MC3|ensembl:ENSP00000404220	intact:EBI-13458|uniprotkb:D6W4B2|ensemblfungi:YPR113W	psi-mi:kash5_human(display_long)|uniprotkb:KASH5(gene name)|psi-mi:KASH5(display_short)|uniprotkb:CCDC155(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 155(gene name synonym)|uniprotkb:KASH domain-containing protein 5(gene name synonym)	psi-mi:pis_yeast(display_long)|uniprotkb:PIS1(gene name)|psi-mi:PIS1(display_short)|uniprotkb:Phosphatidylinositol synthase(gene name synonym)|uniprotkb:PIS(gene name synonym)|uniprotkb:P8283.5(orf name)|uniprotkb:YPR113W(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11522953|imex:IM-24995-72	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_653289.3|ensembl:ENSG00000161609(gene)|ensembl:ENST00000447857(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034397"(telomere localization)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051225"(spindle assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0090172"(microtubule cytoskeleton organization involved in homologous chromosome segregation)|go:"GO:0090220"(chromosome localization to nuclear envelope involved in homologous chromosome segregation)|go:"GO:0090619"(meiotic spindle pole)|interpro:IPR011992(EF-Hand type)|interpro:IPR028168|interpro:IPR028170|interpro:IPR039508|mint:Q8N6L0|rcsb pdb:6R2I|rcsb pdb:6WMF|entrezgene/locuslink:147872(identity)	refseq:NP_015438.1|sgd:S000006317|mint:P06197|dip:DIP-3815N|ensemblfungi:YPR113W(gene)|ensemblfungi:YPR113W_mRNA(transcript)|go:"GO:0003881"(CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000462(CDP-alcohol phosphatidyltransferase)|interpro:IPR014387(CDP-diacylglycerol-inositol 3-phosphatidyltransferase, eukaryote)|interpro:IPR043130|reactome:R-SCE-1483226|sgd:YPR113W(identity)	-	-	crc64:6E2E62252B3CB5E2	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Wl9L7AcvDHCZuKjYLn8QgGIbZTc9606	rogid:tdcTqpKpIDy8+8RRpLxehIeTrRU559292	intact-crc:264EF501B6ADE976|rigid:9RrThZupbs1yPSEiQudQWJFGrpk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P05738	uniprotkb:O14641	intact:EBI-15439|uniprotkb:D6VU02|ensemblfungi:YGL147C	intact:EBI-740850|ensembl:ENSP00000005340|uniprotkb:Q53XM0|uniprotkb:D3DTN3	psi-mi:rl9a_yeast(display_long)|uniprotkb:RPL9A(gene name)|psi-mi:RPL9A(display_short)|uniprotkb:RPL9(gene name synonym)|uniprotkb:RPL8A(gene name synonym)|uniprotkb:L8(gene name synonym)|uniprotkb:YL11(gene name synonym)|uniprotkb:RP24(gene name synonym)|uniprotkb:YGL147C(locus name)|uniprotkb:Large ribosomal subunit protein uL6-A(gene name synonym)	psi-mi:dvl2_human(display_long)|uniprotkb:DSH homolog 2(gene name synonym)|uniprotkb:DVL2(gene name)|psi-mi:DVL2(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11522926|imex:IM-24995-69	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003115|refseq:NP_011368.3|ensemblfungi:YGL147C(gene)|ensemblfungi:YGL147C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0019843"(rRNA binding)|go:"GO:0022625"(cytosolic large ribosomal subunit)|interpro:IPR000702(Ribosomal protein L6)|interpro:IPR002359(Ribosomal protein L6, conserved site-2)|interpro:IPR020040|interpro:IPR036789|rcsb pdb:1K5Y|rcsb pdb:3J16|rcsb pdb:3J6X|rcsb pdb:3J6Y|rcsb pdb:3J77|rcsb pdb:3J78|rcsb pdb:3JCT|rcsb pdb:4U3M|rcsb pdb:4U3N|rcsb pdb:4U3U|rcsb pdb:4U4N|rcsb pdb:4U4O|rcsb pdb:4U4Q|rcsb pdb:4U4R|rcsb pdb:4U4U|rcsb pdb:4U4Y|rcsb pdb:4U4Z|rcsb pdb:4U50|rcsb pdb:4U51|rcsb pdb:4U52|rcsb pdb:4U53|rcsb pdb:4U55|rcsb pdb:4U56|rcsb pdb:4U6F|rcsb pdb:4V4B|rcsb pdb:4V6I|rcsb pdb:4V7F|rcsb pdb:4V7R|rcsb pdb:4V88|rcsb pdb:4V8T|rcsb pdb:4V8Y|rcsb pdb:7NRD|rcsb pdb:4V8Z|rcsb pdb:4V91|rcsb pdb:5APN|rcsb pdb:5APO|rcsb pdb:5DAT|rcsb pdb:5DC3|rcsb pdb:5DGE|rcsb pdb:5DGF|rcsb pdb:5DGV|rcsb pdb:5FCI|rcsb pdb:5FCJ|rcsb pdb:5FL8|rcsb pdb:5GAK|rcsb pdb:5H4P|rcsb pdb:5I4L|rcsb pdb:5JCS|rcsb pdb:5JUO|rcsb pdb:5JUP|rcsb pdb:5JUS|rcsb pdb:5JUT|rcsb pdb:5JUU|rcsb pdb:5LYB|rcsb pdb:5M1J|rcsb pdb:5MC6|rcsb pdb:5MEI|rcsb pdb:5NDG|rcsb pdb:5NDV|rcsb pdb:5NDW|rcsb pdb:5OBM|rcsb pdb:5ON6|rcsb pdb:5T62|rcsb pdb:5T6R|rcsb pdb:5TBW|rcsb pdb:5TGA|rcsb pdb:5TGM|rcsb pdb:5Z3G|rcsb pdb:6ELZ|rcsb pdb:6EM1|rcsb pdb:6EM5|rcsb pdb:6FT6|rcsb pdb:6GQ1|rcsb pdb:6GQB|rcsb pdb:6GQV|rcsb pdb:6HD7|rcsb pdb:6HHQ|rcsb pdb:6I7O|rcsb pdb:6M62|rcsb pdb:6N8J|rcsb pdb:6N8K|rcsb pdb:6N8L|rcsb pdb:6N8M|rcsb pdb:6N8N|rcsb pdb:6N8O|rcsb pdb:6OIG|rcsb pdb:6Q8Y|rcsb pdb:6QIK|rcsb pdb:6QT0|rcsb pdb:6QTZ|rcsb pdb:6R84|rcsb pdb:6R86|rcsb pdb:6R87|rcsb pdb:6RI5|rcsb pdb:6RZZ|rcsb pdb:6S05|rcsb pdb:6S47|rcsb pdb:6SNT|rcsb pdb:6SV4|rcsb pdb:6T4Q|rcsb pdb:6T7I|rcsb pdb:6T7T|rcsb pdb:6T83|rcsb pdb:6TB3|rcsb pdb:6TNU|rcsb pdb:6YLG|rcsb pdb:6YLH|rcsb pdb:6YLX|rcsb pdb:6YLY|rcsb pdb:6Z6J|rcsb pdb:6Z6K|rcsb pdb:7AZY|rcsb pdb:7B7D|rcsb pdb:7BT6|rcsb pdb:7BTB|rcsb pdb:7NRC|dip:DIP-4826N|sgd:YGL147C(identity)	refseq:NP_004413.1|ensembl:ENSG00000004975(gene)|ensembl:ENST00000005340(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005109"(frizzled binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0007507"(heart development)|go:"GO:0016235"(aggresome)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044340"(canonical Wnt signaling pathway involved in regulation of cell proliferation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0150012"(positive regulation of neuron projection arborization)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008341(Dishevelled-2 region)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:O14641|rcsb pdb:2REY|rcsb pdb:3CBX|rcsb pdb:3CBY|rcsb pdb:3CBZ|rcsb pdb:3CC0|rcsb pdb:4WIP|rcsb pdb:5LNP|rcsb pdb:5SUY|rcsb pdb:5SUZ|rcsb pdb:6IW3|rcsb pdb:6JCK|reactome:R-HSA-201681|reactome:R-HSA-201688|reactome:R-HSA-2028269|reactome:R-HSA-4086400|reactome:R-HSA-4608870|reactome:R-HSA-4641258|reactome:R-HSA-4641262|reactome:R-HSA-5099900|reactome:R-HSA-5368598|reactome:R-HSA-5663220|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9673324|ensembl:ENSP00000005340|dip:DIP-34433N|entrezgene/locuslink:1856(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:TCDvdj9QlqdgRadKyIWG7ane1hw559292	rogid:2Vdc8oRnT4Mz/j+EXQXrL3AszOc9606	intact-crc:38B95F622EFA7D05|rigid:KqIOTMa/9fGdg3f2mHv0SPhCTw0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P05738	uniprotkb:Q92997	intact:EBI-15439|uniprotkb:D6VU02|ensemblfungi:YGL147C	intact:EBI-739789|uniprotkb:O14642|uniprotkb:Q13531|uniprotkb:Q8N5E9|uniprotkb:Q92607|uniprotkb:D3DNT0|intact:EBI-11081380|uniprotkb:B4E3E5|ensembl:ENSP00000316054	psi-mi:rl9a_yeast(display_long)|uniprotkb:RPL9A(gene name)|psi-mi:RPL9A(display_short)|uniprotkb:RPL9(gene name synonym)|uniprotkb:RPL8A(gene name synonym)|uniprotkb:L8(gene name synonym)|uniprotkb:YL11(gene name synonym)|uniprotkb:RP24(gene name synonym)|uniprotkb:YGL147C(locus name)|uniprotkb:Large ribosomal subunit protein uL6-A(gene name synonym)	psi-mi:dvl3_human(display_long)|uniprotkb:DVL3(gene name)|psi-mi:DVL3(display_short)|uniprotkb:KIAA0208(gene name synonym)|uniprotkb:DSH homolog 3(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11522935|imex:IM-24995-70	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003115|refseq:NP_011368.3|ensemblfungi:YGL147C(gene)|ensemblfungi:YGL147C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0019843"(rRNA binding)|go:"GO:0022625"(cytosolic large ribosomal subunit)|interpro:IPR000702(Ribosomal protein L6)|interpro:IPR002359(Ribosomal protein L6, conserved site-2)|interpro:IPR020040|interpro:IPR036789|rcsb pdb:1K5Y|rcsb pdb:3J16|rcsb pdb:3J6X|rcsb pdb:3J6Y|rcsb pdb:3J77|rcsb pdb:3J78|rcsb pdb:3JCT|rcsb pdb:4U3M|rcsb pdb:4U3N|rcsb pdb:4U3U|rcsb pdb:4U4N|rcsb pdb:4U4O|rcsb pdb:4U4Q|rcsb pdb:4U4R|rcsb pdb:4U4U|rcsb pdb:4U4Y|rcsb pdb:4U4Z|rcsb pdb:4U50|rcsb pdb:4U51|rcsb pdb:4U52|rcsb pdb:4U53|rcsb pdb:4U55|rcsb pdb:4U56|rcsb pdb:4U6F|rcsb pdb:4V4B|rcsb pdb:4V6I|rcsb pdb:4V7F|rcsb pdb:4V7R|rcsb pdb:4V88|rcsb pdb:4V8T|rcsb pdb:4V8Y|rcsb pdb:7NRD|rcsb pdb:4V8Z|rcsb pdb:4V91|rcsb pdb:5APN|rcsb pdb:5APO|rcsb pdb:5DAT|rcsb pdb:5DC3|rcsb pdb:5DGE|rcsb pdb:5DGF|rcsb pdb:5DGV|rcsb pdb:5FCI|rcsb pdb:5FCJ|rcsb pdb:5FL8|rcsb pdb:5GAK|rcsb pdb:5H4P|rcsb pdb:5I4L|rcsb pdb:5JCS|rcsb pdb:5JUO|rcsb pdb:5JUP|rcsb pdb:5JUS|rcsb pdb:5JUT|rcsb pdb:5JUU|rcsb pdb:5LYB|rcsb pdb:5M1J|rcsb pdb:5MC6|rcsb pdb:5MEI|rcsb pdb:5NDG|rcsb pdb:5NDV|rcsb pdb:5NDW|rcsb pdb:5OBM|rcsb pdb:5ON6|rcsb pdb:5T62|rcsb pdb:5T6R|rcsb pdb:5TBW|rcsb pdb:5TGA|rcsb pdb:5TGM|rcsb pdb:5Z3G|rcsb pdb:6ELZ|rcsb pdb:6EM1|rcsb pdb:6EM5|rcsb pdb:6FT6|rcsb pdb:6GQ1|rcsb pdb:6GQB|rcsb pdb:6GQV|rcsb pdb:6HD7|rcsb pdb:6HHQ|rcsb pdb:6I7O|rcsb pdb:6M62|rcsb pdb:6N8J|rcsb pdb:6N8K|rcsb pdb:6N8L|rcsb pdb:6N8M|rcsb pdb:6N8N|rcsb pdb:6N8O|rcsb pdb:6OIG|rcsb pdb:6Q8Y|rcsb pdb:6QIK|rcsb pdb:6QT0|rcsb pdb:6QTZ|rcsb pdb:6R84|rcsb pdb:6R86|rcsb pdb:6R87|rcsb pdb:6RI5|rcsb pdb:6RZZ|rcsb pdb:6S05|rcsb pdb:6S47|rcsb pdb:6SNT|rcsb pdb:6SV4|rcsb pdb:6T4Q|rcsb pdb:6T7I|rcsb pdb:6T7T|rcsb pdb:6T83|rcsb pdb:6TB3|rcsb pdb:6TNU|rcsb pdb:6YLG|rcsb pdb:6YLH|rcsb pdb:6YLX|rcsb pdb:6YLY|rcsb pdb:6Z6J|rcsb pdb:6Z6K|rcsb pdb:7AZY|rcsb pdb:7B7D|rcsb pdb:7BT6|rcsb pdb:7BTB|rcsb pdb:7NRC|dip:DIP-4826N|sgd:YGL147C(identity)	refseq:NP_004414.3|dip:DIP-34509N|ensembl:ENSG00000161202(gene)|ensembl:ENST00000313143(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002020"(protease binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005109"(frizzled binding)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0038031"(non-canonical Wnt signaling pathway via JNK cascade)|go:"GO:0042493"|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050821"(protein stabilization)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0150012"(positive regulation of neuron projection arborization)|go:"GO:1903827"|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008342(Dishevelled-3 protein, C-terminal)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:Q92997|rcsb pdb:6V7O|rcsb pdb:6ZC6|rcsb pdb:6ZC8|reactome:R-HSA-201681|reactome:R-HSA-201688|reactome:R-HSA-4086400|reactome:R-HSA-4641258|reactome:R-HSA-4641262|reactome:R-HSA-5368598|reactome:R-HSA-5663220|reactome:R-HSA-9673324|entrezgene/locuslink:1857(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:TCDvdj9QlqdgRadKyIWG7ane1hw559292	rogid:yJ3YIp5IhvKTQwa3bK5yTjNyqXk9606	intact-crc:EF468AE31A2C90B2|rigid:zMFEPUFkowDpfM3kSMjbz6SoM/0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P05759	uniprotkb:Q13137	intact:EBI-16127|uniprotkb:P14800|ensemblfungi:YLR167W|uniprotkb:D6VYH3|uniprotkb:P04838|uniprotkb:P61864|uniprotkb:Q6LA96	intact:EBI-739580|uniprotkb:B4DDC4|uniprotkb:E7ENK0|uniprotkb:Q53FQ5|uniprotkb:Q53HB5|uniprotkb:Q6IBN9|uniprotkb:Q9BTF7|uniprotkb:B2RBT0|ensembl:ENSP00000258947|uniprotkb:B4E0C0|uniprotkb:E7ETP5|uniprotkb:B4DDT4|uniprotkb:B4DP36|uniprotkb:E9PBE5	psi-mi:rs31_yeast(display_long)|uniprotkb:RPS31(gene name)|psi-mi:RPS31(display_short)|uniprotkb:UBI3(gene name synonym)|uniprotkb:YLR167W(locus name)|uniprotkb:L9470.14(orf name)|uniprotkb:RPS37(gene name synonym)	psi-mi:caco2_human(display_long)|uniprotkb:CALCOCO2(gene name)|psi-mi:CALCOCO2(display_short)|uniprotkb:NDP52(gene name synonym)|uniprotkb:Nuclear domain 10 protein NDP52(gene name synonym)|uniprotkb:Antigen nuclear dot 52 kDa protein(gene name synonym)|uniprotkb:Nuclear dot protein 52(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11522944|imex:IM-24995-71	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:6WOO|rcsb pdb:6Z6J|rcsb pdb:6Z6K|rcsb pdb:6ZCE|rcsb pdb:6ZQH|rcsb pdb:6ZU9|rcsb pdb:6ZVI|rcsb pdb:7A1G|rcsb pdb:7B7D|rcsb pdb:7NRC|rcsb pdb:7NRD|rcsb pdb:5WYJ|rcsb pdb:6EML|rcsb pdb:6GQ1|rcsb pdb:6GQB|rcsb pdb:6GQV|rcsb pdb:6HHQ|rcsb pdb:6I7O|rcsb pdb:6Q8Y|rcsb pdb:6RBE|rcsb pdb:6S47|rcsb pdb:6SNT|rcsb pdb:6SV4|rcsb pdb:6T4Q|rcsb pdb:6T7I|rcsb pdb:6T7T|rcsb pdb:6T83|rcsb pdb:6TB3|rcsb pdb:6TNU|rcsb pdb:6WDR|ensemblfungi:YLR167W(gene)|ensemblfungi:YLR167W_mRNA(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0002109"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, LSU-rRNA,5S)")|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0031386"(protein tag)|rcsb pdb:4U56|rcsb pdb:4U6F|rcsb pdb:4V88|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0046872"(metal ion binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR002906(Ribosomal protein S27a)|interpro:IPR011332(Ribosomal protein, zinc-binding)|interpro:IPR019954|interpro:IPR019956|interpro:IPR029071|rcsb pdb:4V8Y|interpro:IPR038582|rcsb pdb:3J6X|rcsb pdb:3J6Y|rcsb pdb:3J77|rcsb pdb:4V8Z|rcsb pdb:3J78|rcsb pdb:4U3M|rcsb pdb:4U3N|rcsb pdb:4U3U|rcsb pdb:4U4N|rcsb pdb:4U4O|rcsb pdb:4U4Q|rcsb pdb:4U4R|rcsb pdb:4U4U|rcsb pdb:4U4Y|rcsb pdb:4U4Z|rcsb pdb:4U50|rcsb pdb:4U51|rcsb pdb:4U52|rcsb pdb:4U53|rcsb pdb:4U55|rcsb pdb:4V92|rcsb pdb:5DAT|rcsb pdb:5DC3|rcsb pdb:5DGE|rcsb pdb:5DGF|rcsb pdb:5DGV|rcsb pdb:5FCI|rcsb pdb:5FCJ|rcsb pdb:5I4L|rcsb pdb:5JUO|rcsb pdb:5JUP|rcsb pdb:5JUS|rcsb pdb:5JUT|rcsb pdb:5JUU|rcsb pdb:5L6H|rcsb pdb:5L6I|rcsb pdb:5L6J|rcsb pdb:5LYB|rcsb pdb:5M1J|rcsb pdb:5MC6|rcsb pdb:5NDG|rcsb pdb:5NDW|rcsb pdb:5OBM|rcsb pdb:5TGA|rcsb pdb:5TGM|rcsb pdb:5U4P|refseq:NP_013268.1|sgd:S000004157|dip:DIP-6389N|mint:P05759|sgd:YLR167W(identity)	refseq:NP_001248319.1|refseq:NP_001248320.1|refseq:NP_001248322.1|refseq:NP_005822.1|ensembl:ENSG00000136436(gene)|ensembl:ENST00000258947(transcript)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016032"(viral process)|go:"GO:0016605"(PML body)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0098792"(xenophagy)|go:"GO:1901098"(positive regulation of autophagosome maturation)|interpro:IPR041611|interpro:IPR041641|mint:Q13137|rcsb pdb:2MXP|rcsb pdb:3VVV|rcsb pdb:3VVW|rcsb pdb:4GXL|rcsb pdb:4HAN|rcsb pdb:4XKL|rcsb pdb:5AAQ|rcsb pdb:5Z7A|rcsb pdb:5Z7L|refseq:NP_001248324.1|dip:DIP-57534N|entrezgene/locuslink:10241(identity)	-	-	crc64:609B121DA1A9DCB8	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:y4P4l0xJoM/1nElb1uDDTpc3oJA559292	rogid:N/GPJUGBK+Dh5Cg+csmafphuo9M9606	intact-crc:03F4B191956689B4|rigid:uJnikN2n0oe5MdDeAivESK4TArY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P06782	uniprotkb:Q9UKT9	intact:EBI-17516|uniprotkb:D6VTA0|ensemblfungi:YDR477W	intact:EBI-747204|uniprotkb:Q8WWQ9|uniprotkb:Q8WWR0|uniprotkb:Q8WWR1|uniprotkb:Q8WWR2|uniprotkb:Q8WWR3|uniprotkb:Q8N574|uniprotkb:B4DVV5|uniprotkb:Q69BL6|uniprotkb:Q69BL7|uniprotkb:Q69BL8|uniprotkb:Q69BL9|uniprotkb:Q69BM0|uniprotkb:Q69BM1|uniprotkb:Q69BM2|uniprotkb:Q69BM3|uniprotkb:Q69BM5|ensembl:ENSP00000344544	psi-mi:snf1_yeast(display_long)|uniprotkb:SNF1(gene name)|psi-mi:SNF1(display_short)|uniprotkb:CAT1(gene name synonym)|uniprotkb:CCR1(gene name synonym)|uniprotkb:GLC2(gene name synonym)|uniprotkb:PAS14(gene name synonym)|uniprotkb:Sucrose nonfermentating protein 1(gene name synonym)|uniprotkb:D8035.20(orf name)|uniprotkb:YDR477W(locus name)	psi-mi:ikzf3_human(display_long)|uniprotkb:ZNFN1A3(gene name synonym)|uniprotkb:Ikaros family zinc finger protein 3(gene name synonym)|uniprotkb:IKZF3(gene name)|psi-mi:IKZF3(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11523031|imex:IM-24995-80	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010765.3|sgd:S000002885|ensemblfungi:YDR477W(gene)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0071940"(fungal-type cell wall assembly)|go:"GO:0090606"(single-species surface biofilm formation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900436"(positive regulation of filamentous growth of a population of unicellular organisms in response to starvation)|go:"GO:2000222"(positive regulation of pseudohyphal growth)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013896(Ubiquitin-associated region 2)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR028375|interpro:IPR032270|rcsb pdb:2FH9|rcsb pdb:2QLV|rcsb pdb:3DAE|rcsb pdb:3HYH|rcsb pdb:3MN3|rcsb pdb:3T4N|rcsb pdb:3TDH|rcsb pdb:3TE5|reactome:R-SCE-1632852|reactome:R-SCE-163680|reactome:R-SCE-200425|reactome:R-SCE-380972|ensemblfungi:YDR477W_mRNA(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000144"(cellular bud neck septin ring)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004679"(AMP-activated protein kinase activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005641"(nuclear envelope lumen)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0007155"(cell adhesion)|go:"GO:0016239"(positive regulation of macroautophagy)|dip:DIP-18N|mint:P06782|sgd:YDR477W(identity)	refseq:NP_001271443.1|refseq:NP_001271444.1|refseq:NP_036613.2|refseq:NP_899051.1|refseq:NP_899052.1|refseq:NP_899053.1|refseq:NP_899054.1|refseq:NP_899055.1|refseq:NP_001271445.1|refseq:NP_001244337.1|refseq:NP_001244338.1|refseq:NP_001244339.1|refseq:NP_001244340.1|refseq:NP_001244341.1|refseq:NP_001244342.1|refseq:NP_001244343.1|ensembl:ENSG00000161405(gene)|ensembl:ENST00000346872(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007498"(mesoderm development)|go:"GO:0009617"(response to bacterium)|go:"GO:0030888"(regulation of B cell proliferation)|go:"GO:0042113"(B cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045577"(regulation of B cell differentiation)|go:"GO:0045619"(regulation of lymphocyte differentiation)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|go:"GO:0046872"(metal ion binding)|dip:DIP-56975N|entrezgene/locuslink:22806(identity)	-	crc64:F5C63565C986C4E3	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:O/SAW1kJE3fpoXPHGLG01i9RePs559292	rogid:2Kp6LefSLfK5VIiE6DmQusFIfMY9606	intact-crc:0948A4DE91D1BDDD|rigid:lqfFs/MV9M4ricnpIgL3cu1sG64	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P06782	uniprotkb:Q9BQ66	intact:EBI-17516|uniprotkb:D6VTA0|ensemblfungi:YDR477W	intact:EBI-739863|uniprotkb:A3KMC5|uniprotkb:Q495I0|ensembl:ENSP00000377582|ensembl:ENSP00000458979	psi-mi:snf1_yeast(display_long)|uniprotkb:SNF1(gene name)|psi-mi:SNF1(display_short)|uniprotkb:CAT1(gene name synonym)|uniprotkb:CCR1(gene name synonym)|uniprotkb:GLC2(gene name synonym)|uniprotkb:PAS14(gene name synonym)|uniprotkb:Sucrose nonfermentating protein 1(gene name synonym)|uniprotkb:D8035.20(orf name)|uniprotkb:YDR477W(locus name)	psi-mi:kr412_human(display_long)|uniprotkb:KRTAP4-12(gene name)|psi-mi:KRTAP4-12(display_short)|uniprotkb:KAP4.12(gene name synonym)|uniprotkb:KRTAP4.12(gene name synonym)|uniprotkb:Keratin-associated protein 4.12(gene name synonym)|uniprotkb:Ultrahigh sulfur keratin-associated protein 4.12(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11523022|imex:IM-24995-79	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010765.3|sgd:S000002885|ensemblfungi:YDR477W(gene)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0071940"(fungal-type cell wall assembly)|go:"GO:0090606"(single-species surface biofilm formation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900436"(positive regulation of filamentous growth of a population of unicellular organisms in response to starvation)|go:"GO:2000222"(positive regulation of pseudohyphal growth)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013896(Ubiquitin-associated region 2)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR028375|interpro:IPR032270|rcsb pdb:2FH9|rcsb pdb:2QLV|rcsb pdb:3DAE|rcsb pdb:3HYH|rcsb pdb:3MN3|rcsb pdb:3T4N|rcsb pdb:3TDH|rcsb pdb:3TE5|reactome:R-SCE-1632852|reactome:R-SCE-163680|reactome:R-SCE-200425|reactome:R-SCE-380972|ensemblfungi:YDR477W_mRNA(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000144"(cellular bud neck septin ring)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004679"(AMP-activated protein kinase activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005641"(nuclear envelope lumen)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0007155"(cell adhesion)|go:"GO:0016239"(positive regulation of macroautophagy)|dip:DIP-18N|mint:P06782|sgd:YDR477W(identity)	refseq:NP_114060.1|ensembl:ENSG00000213416(gene)|ensembl:ENSG00000263236(gene)|ensembl:ENST00000394014(transcript)|ensembl:ENST00000571271(transcript)|go:"GO:0045095"(keratin filament)|interpro:IPR002494(Keratin, high sulphur B2 protein)|entrezgene/locuslink:83755(identity)	-	crc64:F5C63565C986C4E3	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:O/SAW1kJE3fpoXPHGLG01i9RePs559292	rogid:XLiYOwNd549kn287BJWgx5zmDCY9606	intact-crc:740906B944766AD8|rigid:aFoJnKS6fhMQMaDuej7AMRvcy2c	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q99750	uniprotkb:P06782	intact:EBI-724076|ensembl:ENSP00000230321|ensembl:ENSP00000362142	intact:EBI-17516|uniprotkb:D6VTA0|ensemblfungi:YDR477W	psi-mi:mdfi_human(display_long)|uniprotkb:Myogenic repressor I-mf(gene name synonym)|uniprotkb:MDFI(gene name)|psi-mi:MDFI(display_short)	psi-mi:snf1_yeast(display_long)|uniprotkb:SNF1(gene name)|psi-mi:SNF1(display_short)|uniprotkb:CAT1(gene name synonym)|uniprotkb:CCR1(gene name synonym)|uniprotkb:GLC2(gene name synonym)|uniprotkb:PAS14(gene name synonym)|uniprotkb:Sucrose nonfermentating protein 1(gene name synonym)|uniprotkb:D8035.20(orf name)|uniprotkb:YDR477W(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11523013|imex:IM-24995-78	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005577.1|ensembl:ENSG00000112559(gene)|ensembl:ENST00000230321(transcript)|ensembl:ENST00000373051(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR026134|mint:Q99750|refseq:NP_001287733.1|refseq:NP_001287734.1|refseq:NP_001287735.1|entrezgene/locuslink:4188(identity)	refseq:NP_010765.3|sgd:S000002885|ensemblfungi:YDR477W(gene)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0071940"(fungal-type cell wall assembly)|go:"GO:0090606"(single-species surface biofilm formation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900436"(positive regulation of filamentous growth of a population of unicellular organisms in response to starvation)|go:"GO:2000222"(positive regulation of pseudohyphal growth)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013896(Ubiquitin-associated region 2)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR028375|interpro:IPR032270|rcsb pdb:2FH9|rcsb pdb:2QLV|rcsb pdb:3DAE|rcsb pdb:3HYH|rcsb pdb:3MN3|rcsb pdb:3T4N|rcsb pdb:3TDH|rcsb pdb:3TE5|reactome:R-SCE-1632852|reactome:R-SCE-163680|reactome:R-SCE-200425|reactome:R-SCE-380972|ensemblfungi:YDR477W_mRNA(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000144"(cellular bud neck septin ring)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004679"(AMP-activated protein kinase activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005641"(nuclear envelope lumen)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0007155"(cell adhesion)|go:"GO:0016239"(positive regulation of macroautophagy)|dip:DIP-18N|mint:P06782|sgd:YDR477W(identity)	-	-	crc64:F5C63565C986C4E3	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:V3vU0fihMOW18DMHAiDbuZ3asNU9606	rogid:O/SAW1kJE3fpoXPHGLG01i9RePs559292	intact-crc:2A790A1A79579589|rigid:cSDwEv05Wb9pdoi2U44eYzMbaHM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P06782	uniprotkb:Q8N5R6	intact:EBI-17516|uniprotkb:D6VTA0|ensemblfungi:YDR477W	intact:EBI-740841|intact:EBI-953781|uniprotkb:B3KQ49|uniprotkb:A8K3U4|uniprotkb:A8MPQ6|uniprotkb:A8MV61|uniprotkb:A8MVU9|uniprotkb:Q9H5Q6|uniprotkb:Q8TAX6|intact:EBI-2320546|intact:EBI-11522976	psi-mi:snf1_yeast(display_long)|uniprotkb:SNF1(gene name)|psi-mi:SNF1(display_short)|uniprotkb:CAT1(gene name synonym)|uniprotkb:CCR1(gene name synonym)|uniprotkb:GLC2(gene name synonym)|uniprotkb:PAS14(gene name synonym)|uniprotkb:Sucrose nonfermentating protein 1(gene name synonym)|uniprotkb:D8035.20(orf name)|uniprotkb:YDR477W(locus name)	psi-mi:ccd33_human(display_long)|uniprotkb:CCDC33(gene name)|psi-mi:CCDC33(display_short)|uniprotkb:Cancer/testis antigen 61(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11522974|imex:IM-24995-74	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010765.3|sgd:S000002885|ensemblfungi:YDR477W(gene)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0071940"(fungal-type cell wall assembly)|go:"GO:0090606"(single-species surface biofilm formation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900436"(positive regulation of filamentous growth of a population of unicellular organisms in response to starvation)|go:"GO:2000222"(positive regulation of pseudohyphal growth)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013896(Ubiquitin-associated region 2)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR028375|interpro:IPR032270|rcsb pdb:2FH9|rcsb pdb:2QLV|rcsb pdb:3DAE|rcsb pdb:3HYH|rcsb pdb:3MN3|rcsb pdb:3T4N|rcsb pdb:3TDH|rcsb pdb:3TE5|reactome:R-SCE-1632852|reactome:R-SCE-163680|reactome:R-SCE-200425|reactome:R-SCE-380972|ensemblfungi:YDR477W_mRNA(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000144"(cellular bud neck septin ring)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004679"(AMP-activated protein kinase activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005641"(nuclear envelope lumen)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0007155"(cell adhesion)|go:"GO:0016239"(positive regulation of macroautophagy)|dip:DIP-18N|mint:P06782|sgd:YDR477W(identity)	refseq:NP_079331.3|interpro:IPR000008(C2 calcium-dependent membrane targeting)|go:"GO:0005777"(peroxisome)|refseq:NP_001274110.1|refseq:NP_877592.2|mint:Q8N5R6|interpro:IPR035892|interpro:IPR039889|entrezgene/locuslink:80125(identity)	-	crc64:F5C63565C986C4E3	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2021/11/30	rogid:O/SAW1kJE3fpoXPHGLG01i9RePs559292	rogid:eEIn7pQyfdHWx8TeLJpYy0i/gww9606	intact-crc:4FA3868550479D44|rigid:ZRLG728wbypxjsqZJneIKHvxyVk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P06782	uniprotkb:P14373	intact:EBI-17516|uniprotkb:D6VTA0|ensemblfungi:YDR477W	intact:EBI-719493|uniprotkb:A2BE15|uniprotkb:Q5RJA8|uniprotkb:Q5ST26|uniprotkb:Q6LA73|uniprotkb:Q6NXR9|uniprotkb:Q9BZY6|uniprotkb:Q9UJL3|ensembl:ENSP00000383555|ensembl:ENSP00000392787|ensembl:ENSP00000405229|ensembl:ENSP00000414793|ensembl:ENSP00000366404	psi-mi:snf1_yeast(display_long)|uniprotkb:SNF1(gene name)|psi-mi:SNF1(display_short)|uniprotkb:CAT1(gene name synonym)|uniprotkb:CCR1(gene name synonym)|uniprotkb:GLC2(gene name synonym)|uniprotkb:PAS14(gene name synonym)|uniprotkb:Sucrose nonfermentating protein 1(gene name synonym)|uniprotkb:D8035.20(orf name)|uniprotkb:YDR477W(locus name)	psi-mi:tri27_human(display_long)|uniprotkb:TRIM27(gene name)|psi-mi:TRIM27(display_short)|uniprotkb:RNF76(gene name synonym)|uniprotkb:RFP(gene name synonym)|uniprotkb:Ret finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 27(gene name synonym)|uniprotkb:RING finger protein 76(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM27(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11522995|imex:IM-24995-76	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010765.3|sgd:S000002885|ensemblfungi:YDR477W(gene)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0071940"(fungal-type cell wall assembly)|go:"GO:0090606"(single-species surface biofilm formation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900436"(positive regulation of filamentous growth of a population of unicellular organisms in response to starvation)|go:"GO:2000222"(positive regulation of pseudohyphal growth)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013896(Ubiquitin-associated region 2)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR028375|interpro:IPR032270|rcsb pdb:2FH9|rcsb pdb:2QLV|rcsb pdb:3DAE|rcsb pdb:3HYH|rcsb pdb:3MN3|rcsb pdb:3T4N|rcsb pdb:3TDH|rcsb pdb:3TE5|reactome:R-SCE-1632852|reactome:R-SCE-163680|reactome:R-SCE-200425|reactome:R-SCE-380972|ensemblfungi:YDR477W_mRNA(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000144"(cellular bud neck septin ring)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004679"(AMP-activated protein kinase activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005641"(nuclear envelope lumen)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0007155"(cell adhesion)|go:"GO:0016239"(positive regulation of macroautophagy)|dip:DIP-18N|mint:P06782|sgd:YDR477W(identity)	refseq:NP_006501.1|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0090281"(negative regulation of calcium ion import)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR020457|interpro:IPR035791|interpro:IPR043136|mint:P14373|reactome:R-HSA-3232142|reactome:R-HSA-9635465|reactome:R-HSA-8948751|ensembl:ENSG00000204713(gene)|ensembl:ENSG00000215641(gene)|ensembl:ENSG00000229006(gene)|ensembl:ENSG00000234495(gene)|ensembl:ENSG00000237071(gene)|ensembl:ENST00000377199(transcript)|ensembl:ENST00000400720(transcript)|ensembl:ENST00000431123(transcript)|ensembl:ENST00000435528(transcript)|ensembl:ENST00000437160(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001650"(fibrillar center)|go:"GO:0002820"(negative regulation of adaptive immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|entrezgene/locuslink:5987(identity)	-	crc64:F5C63565C986C4E3	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:O/SAW1kJE3fpoXPHGLG01i9RePs559292	rogid:dsfH5OUghD8KSaTz1SFw9OYVTK49606	intact-crc:1DA6EE03CCE1932F|rigid:h7VfHQetYAIiUYbPMZSfzqd4VHM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O43597	uniprotkb:P06782	intact:EBI-742487|uniprotkb:Q5T6Z7|ensembl:ENSP00000366306|ensembl:ENSP00000366308|uniprotkb:B2R9J9	intact:EBI-17516|uniprotkb:D6VTA0|ensemblfungi:YDR477W	psi-mi:spy2_human(display_long)|uniprotkb:SPRY2(gene name)|psi-mi:SPRY2(display_short)	psi-mi:snf1_yeast(display_long)|uniprotkb:SNF1(gene name)|psi-mi:SNF1(display_short)|uniprotkb:CAT1(gene name synonym)|uniprotkb:CCR1(gene name synonym)|uniprotkb:GLC2(gene name synonym)|uniprotkb:PAS14(gene name synonym)|uniprotkb:Sucrose nonfermentating protein 1(gene name synonym)|uniprotkb:D8035.20(orf name)|uniprotkb:YDR477W(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11522986|imex:IM-24995-75	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005833.1|rcsb pdb:5HL0|reactome:R-HSA-1295596|reactome:R-HSA-182971|rcsb pdb:5HKZ|ensembl:ENST00000377102(transcript)|ensembl:ENST00000377104(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|ensembl:ENSG00000136158(gene)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030291"(protein serine/threonine kinase inhibitor activity)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031345"(negative regulation of cell projection organization)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0032587"(ruffle membrane)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0045165"(cell fate commitment)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048513"(animal organ development)|go:"GO:0051387"(negative regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060437"(lung growth)|go:"GO:0060449"(bud elongation involved in lung branching)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:1900747"(negative regulation of vascular endothelial growth factor signaling pathway)|go:"GO:1902747"(negative regulation of lens fiber cell differentiation)|go:"GO:1990752"(microtubule end)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR007875(Sprouty)|interpro:IPR030780|mint:O43597|rcsb pdb:3BUM|rcsb pdb:3OB1|rcsb pdb:5HKY|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|refseq:NP_001305465.1|refseq:NP_001305466.1|refseq:NP_001305467.1|entrezgene/locuslink:10253(identity)	refseq:NP_010765.3|sgd:S000002885|ensemblfungi:YDR477W(gene)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0071940"(fungal-type cell wall assembly)|go:"GO:0090606"(single-species surface biofilm formation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900436"(positive regulation of filamentous growth of a population of unicellular organisms in response to starvation)|go:"GO:2000222"(positive regulation of pseudohyphal growth)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013896(Ubiquitin-associated region 2)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR028375|interpro:IPR032270|rcsb pdb:2FH9|rcsb pdb:2QLV|rcsb pdb:3DAE|rcsb pdb:3HYH|rcsb pdb:3MN3|rcsb pdb:3T4N|rcsb pdb:3TDH|rcsb pdb:3TE5|reactome:R-SCE-1632852|reactome:R-SCE-163680|reactome:R-SCE-200425|reactome:R-SCE-380972|ensemblfungi:YDR477W_mRNA(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000144"(cellular bud neck septin ring)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004679"(AMP-activated protein kinase activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005641"(nuclear envelope lumen)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0007155"(cell adhesion)|go:"GO:0016239"(positive regulation of macroautophagy)|dip:DIP-18N|mint:P06782|sgd:YDR477W(identity)	-	-	crc64:F5C63565C986C4E3	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:u1omauzisc6MdZlogMotUmtauSI9606	rogid:O/SAW1kJE3fpoXPHGLG01i9RePs559292	intact-crc:7E2B101963F3FF83|rigid:/pIvrusIwTiKh0zizHtESKccyf0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P54619	uniprotkb:P06782	intact:EBI-1181439|ensembl:ENSP00000447433|uniprotkb:B4DDT7|uniprotkb:Q8N7V9	intact:EBI-17516|uniprotkb:D6VTA0|ensemblfungi:YDR477W	psi-mi:aakg1_human(display_long)|uniprotkb:PRKAG1(gene name)|psi-mi:PRKAG1(display_short)	psi-mi:snf1_yeast(display_long)|uniprotkb:SNF1(gene name)|psi-mi:SNF1(display_short)|uniprotkb:CAT1(gene name synonym)|uniprotkb:CCR1(gene name synonym)|uniprotkb:GLC2(gene name synonym)|uniprotkb:PAS14(gene name synonym)|uniprotkb:Sucrose nonfermentating protein 1(gene name synonym)|uniprotkb:D8035.20(orf name)|uniprotkb:YDR477W(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11523004|imex:IM-24995-77	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001193638.1|refseq:NP_001193639.1|refseq:NP_002724.1|refseq:XP_011536864.1|reactome:R-HSA-9619483|reactome:R-HSA-9613354|ensembl:ENSG00000181929(gene)|ensembl:ENST00000548065(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004691"(cAMP-dependent protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006110"(regulation of glycolytic process)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008603"(cAMP-dependent protein kinase regulator activity)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016208"(AMP binding)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0043531"(ADP binding)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051170"(import into nucleus)|go:"GO:0071900"(regulation of protein serine/threonine kinase activity)|interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR039166|mint:P54619|rcsb pdb:2UV4|rcsb pdb:2UV5|rcsb pdb:2UV6|rcsb pdb:2UV7|rcsb pdb:4CFE|rcsb pdb:4CFF|rcsb pdb:4RER|rcsb pdb:4REW|rcsb pdb:4ZHX|rcsb pdb:5EZV|rcsb pdb:5ISO|rcsb pdb:6B1U|rcsb pdb:6B2E|rcsb pdb:6C9F|rcsb pdb:6C9G|rcsb pdb:6C9H|rcsb pdb:6C9J|reactome:R-HSA-1445148|reactome:R-HSA-1632852|reactome:R-HSA-2151209|reactome:R-HSA-380972|reactome:R-HSA-5628897|reactome:R-HSA-6804756|refseq:XP_006719562.1|dip:DIP-39974N|entrezgene/locuslink:5571(identity)	refseq:NP_010765.3|sgd:S000002885|ensemblfungi:YDR477W(gene)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0071940"(fungal-type cell wall assembly)|go:"GO:0090606"(single-species surface biofilm formation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900436"(positive regulation of filamentous growth of a population of unicellular organisms in response to starvation)|go:"GO:2000222"(positive regulation of pseudohyphal growth)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013896(Ubiquitin-associated region 2)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR028375|interpro:IPR032270|rcsb pdb:2FH9|rcsb pdb:2QLV|rcsb pdb:3DAE|rcsb pdb:3HYH|rcsb pdb:3MN3|rcsb pdb:3T4N|rcsb pdb:3TDH|rcsb pdb:3TE5|reactome:R-SCE-1632852|reactome:R-SCE-163680|reactome:R-SCE-200425|reactome:R-SCE-380972|ensemblfungi:YDR477W_mRNA(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000144"(cellular bud neck septin ring)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004679"(AMP-activated protein kinase activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005641"(nuclear envelope lumen)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0007155"(cell adhesion)|go:"GO:0016239"(positive regulation of macroautophagy)|dip:DIP-18N|mint:P06782|sgd:YDR477W(identity)	-	-	crc64:F5C63565C986C4E3	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:JNBzPdCbcgr37RKb2sk6yVL+7649606	rogid:O/SAW1kJE3fpoXPHGLG01i9RePs559292	intact-crc:B564EF04F544D7D8|rigid:IgHiISYAnTxvf0XuRQBFtsbYGuE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P0CD91	uniprotkb:Q8N6L0	intact:EBI-3820350|uniprotkb:O74680|uniprotkb:P53386|uniprotkb:D6W4J2|ensemblfungi:YPR192W	intact:EBI-749265|uniprotkb:Q96MC3|ensembl:ENSP00000404220	psi-mi:aqy1_yeast(display_long)|uniprotkb:AQY1(gene name)|psi-mi:AQY1(display_short)|uniprotkb:AQY1-2(gene name synonym)|uniprotkb:P9677.5(orf name)|uniprotkb:YPR192W(locus name)	psi-mi:kash5_human(display_long)|uniprotkb:KASH5(gene name)|psi-mi:KASH5(display_short)|uniprotkb:CCDC155(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 155(gene name synonym)|uniprotkb:KASH domain-containing protein 5(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11523095|imex:IM-24995-86	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR034294|refseq:NP_015518.1|sgd:S000006396|interpro:IPR023271|interpro:IPR000425(Major intrinsic protein)|interpro:IPR022357|ensemblfungi:YPR192W(gene)|ensemblfungi:YPR192W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006833"(water transport)|go:"GO:0015250"(water channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030437"(ascospore formation)|go:"GO:0055085"(transmembrane transport)|sgd:YPR192W(identity)	refseq:NP_653289.3|ensembl:ENSG00000161609(gene)|ensembl:ENST00000447857(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034397"(telomere localization)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051225"(spindle assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0090172"(microtubule cytoskeleton organization involved in homologous chromosome segregation)|go:"GO:0090220"(chromosome localization to nuclear envelope involved in homologous chromosome segregation)|go:"GO:0090619"(meiotic spindle pole)|interpro:IPR011992(EF-Hand type)|interpro:IPR028168|interpro:IPR028170|interpro:IPR039508|mint:Q8N6L0|rcsb pdb:6R2I|rcsb pdb:6WMF|entrezgene/locuslink:147872(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:SJZXHf9xXd6KcuK51HURax8JgsY559292	rogid:Wl9L7AcvDHCZuKjYLn8QgGIbZTc9606	intact-crc:6B7CF14DC83E441F|rigid:nKqk8JDYCD82tNVDhnNg9XNSiyA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P09435	uniprotkb:Q9NZL4	intact:EBI-8611|uniprotkb:P18862|uniprotkb:D6VPS7|ensemblfungi:YBL075C	intact:EBI-356763|uniprotkb:O95351|uniprotkb:Q6ZNU5|uniprotkb:B3KQP0|uniprotkb:B4DG11|ensembl:ENSP00000255631|ensembl:ENSP00000398244|ensembl:ENSP00000467574	psi-mi:hsp73_yeast(display_long)|uniprotkb:YBL06.07(orf name)|uniprotkb:YBL0610(orf name)|uniprotkb:YBL075C(locus name)|uniprotkb:SSA3(gene name)|psi-mi:SSA3(display_short)	psi-mi:hpbp1_human(display_long)|uniprotkb:HSPBP1(gene name)|psi-mi:HSPBP1(display_short)|uniprotkb:HSPBP(gene name synonym)|uniprotkb:PP1845(orf name)|uniprotkb:Heat shock protein-binding protein 1(gene name synonym)|uniprotkb:Hsp70-interacting protein 1(gene name synonym)|uniprotkb:Hsp70-binding protein 2(gene name synonym)|uniprotkb:Hsp70-interacting protein 2(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11523080|imex:IM-24995-85	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009478.1|sgd:S000000171|mint:P09435|dip:DIP-2266N|ensemblfungi:YBL075C(gene)|ensemblfungi:YBL075C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|sgd:YBL075C(identity)	refseq:NP_001123578.1|refseq:NP_036399.3|ensembl:ENSG00000133265(gene)|ensembl:ENST00000255631(transcript)|ensembl:ENST00000433386(transcript)|ensembl:ENST00000587922(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006457"(protein folding)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013918(Nucleotide exchange factor Fes1)|interpro:IPR016024(Armadillo-type fold)|mint:Q9NZL4|rcsb pdb:1XQR|rcsb pdb:1XQS|refseq:NP_001284529.1|refseq:XP_016882033.1|entrezgene/locuslink:23640(identity)	-	crc64:F4B136759B7D4636	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2018/09/20	rogid:u3ayjvFHnVNMMrDZdrB7NWaGzBg559292	rogid:26Au2GesO5ysT/yhYX/0oOO9Md89606	intact-crc:A1B9CDE4485A5D78|rigid:dUh2qq010WSAE0IUFY/aCrP3YqM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P06787	uniprotkb:O94983-5	intact:EBI-3976|uniprotkb:D6VQA8|ensemblfungi:YBR109C	intact:EBI-10176008	psi-mi:calm_yeast(display_long)|uniprotkb:YBR0904(orf name)|uniprotkb:YBR109C(locus name)|uniprotkb:CMD1(gene name)|psi-mi:CMD1(display_short)	psi-mi:o94983-5(display_long)|uniprotkb:KIAA0909(gene name synonym)|uniprotkb:CAMTA2(gene name)|psi-mi:CAMTA2(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11523040|imex:IM-24995-81	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009667.1|sgd:S000000313|dip:DIP-536N|mint:P06787|ensemblfungi:YBR109C(gene)|ensemblfungi:YBR109C_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0000742"(karyogamy involved in conjugation with cellular fusion)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005823"(central plaque of spindle pole body)|go:"GO:0005933"(cellular bud)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0006897"(endocytosis)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007114"(cell budding)|go:"GO:0016237"(lysosomal microautophagy)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0042144"(vacuole fusion, non-autophagic)|go:"GO:0043332"(mating projection tip)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051019"(mitogen-activated protein kinase binding)|go:"GO:0051300"(spindle pole body organization)|go:"GO:1903525"(regulation of membrane tubulation)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR039030|rcsb pdb:1F54|rcsb pdb:1F55|rcsb pdb:1LKJ|rcsb pdb:2LHH|rcsb pdb:2LHI|rcsb pdb:6OQQ|reactome:R-SCE-111932|reactome:R-SCE-114608|reactome:R-SCE-1474151|reactome:R-SCE-203615|reactome:R-SCE-2871809|reactome:R-SCE-4086398|reactome:R-SCE-442729|reactome:R-SCE-5218920|reactome:R-SCE-5607763|reactome:R-SCE-5626467|reactome:R-SCE-6798695|reactome:R-SCE-9009391|reactome:R-SCE-9619229|sgd:YBR109C(identity)	intact:EBI-936534(isoform-parent)|uniprotkb:O94983-5(isoform-parent)|entrezgene/locuslink:23125(identity)	-	crc64:819ED1AD5D9400D3	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:jyNQ4XuG4o2uZi6ztTIMCcgbQFM559292	rogid:vzdEZ0CgkqevyH4Na04MPr4O6TM9606	intact-crc:5BE477905805A43E|rigid:15hU7apRfQRdlXDSqgd2L1/aR6k	false	-	sufficient binding region:109-329	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P09467	uniprotkb:P09201	intact:EBI-712740|ensembl:ENSP00000364475|ensembl:ENSP00000408025|uniprotkb:O75571|uniprotkb:Q53F94|uniprotkb:Q96E46	intact:EBI-6744|uniprotkb:D6VZ13|ensemblfungi:YLR377C	psi-mi:f16p1_human(display_long)|uniprotkb:D-fructose-1,6-bisphosphate 1-phosphohydrolase 1(gene name synonym)|uniprotkb:FBP1(gene name)|psi-mi:FBP1(display_short)|uniprotkb:FBP(gene name synonym)|uniprotkb:Liver FBPase(gene name synonym)	psi-mi:f16p_yeast(display_long)|uniprotkb:FBP1(gene name)|psi-mi:FBP1(display_short)|uniprotkb:YLR377C(locus name)|uniprotkb:L8039.18(orf name)|uniprotkb:D-fructose-1,6-bisphosphate 1-phosphohydrolase(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11523062|imex:IM-24995-83	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000375326(transcript)|ensembl:ENST00000415431(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005986"(sucrose biosynthetic process)|go:"GO:0006000"(fructose metabolic process)|go:"GO:0006002"(fructose 6-phosphate metabolic process)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006111"(regulation of gluconeogenesis)|go:"GO:0016208"(AMP binding)|go:"GO:0016311"(dephosphorylation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030388"(fructose 1,6-bisphosphate metabolic process)|go:"GO:0035690"|go:"GO:0042132"(fructose 1,6-bisphosphate 1-phosphatase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0045820"(negative regulation of glycolytic process)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0046872"(metal ion binding)|go:"GO:0048029"(monosaccharide binding)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071286"(cellular response to magnesium ion)|interpro:IPR000146(Inositol phosphatase/fructose-1,6-bisphosphatase)|interpro:IPR020548|interpro:IPR028343|interpro:IPR033391|interpro:IPR044015|mint:P09467|rcsb pdb:1FTA|rcsb pdb:2FHY|rcsb pdb:2FIE|rcsb pdb:2FIX|rcsb pdb:2JJK|rcsb pdb:2VT5|rcsb pdb:2WBB|rcsb pdb:2WBD|rcsb pdb:2Y5K|rcsb pdb:2Y5L|rcsb pdb:3A29|rcsb pdb:3KBZ|rcsb pdb:3KC0|ensembl:ENSG00000165140(gene)|rcsb pdb:3KC1|rcsb pdb:4MJO|rcsb pdb:5LDZ|rcsb pdb:5PZR|rcsb pdb:5PZS|rcsb pdb:5PZT|rcsb pdb:5PZU|rcsb pdb:5PZV|rcsb pdb:5PZW|rcsb pdb:5PZX|rcsb pdb:5PZY|rcsb pdb:5PZZ|rcsb pdb:5Q00|rcsb pdb:5Q01|rcsb pdb:5Q02|rcsb pdb:5Q03|rcsb pdb:5Q04|rcsb pdb:5Q05|rcsb pdb:5Q06|rcsb pdb:5Q07|rcsb pdb:5Q08|rcsb pdb:5Q09|rcsb pdb:5PZQ|rcsb pdb:5Q0A|rcsb pdb:5Q0B|rcsb pdb:6LS5|rcsb pdb:6LW2|rcsb pdb:7C9Q|rcsb pdb:7CVN|reactome:R-HSA-70263|refseq:NP_000498.2|refseq:NP_001121100.1|dip:DIP-46677N|entrezgene/locuslink:2203(identity)	refseq:NP_013481.3|sgd:S000004369|dip:DIP-3986N|mint:P09201|ensemblfungi:YLR377C(gene)|ensemblfungi:YLR377C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005986"(sucrose biosynthetic process)|go:"GO:0006000"(fructose metabolic process)|go:"GO:0006002"(fructose 6-phosphate metabolic process)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0030388"(fructose 1,6-bisphosphate metabolic process)|go:"GO:0042132"(fructose 1,6-bisphosphate 1-phosphatase activity)|go:"GO:0042597"(periplasmic space)|go:"GO:0046872"(metal ion binding)|go:"GO:0072593"(reactive oxygen species metabolic process)|interpro:IPR000146(Inositol phosphatase/fructose-1,6-bisphosphatase)|interpro:IPR020548|interpro:IPR028343|interpro:IPR033391|interpro:IPR044015|rcsb pdb:7NS5|reactome:R-SCE-70263|sgd:YLR377C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:DnrtyrU5WL/7ut1qWv7LndveJT89606	rogid:hvvSZcZrdcN9FcOmFzY/jCYIcJY559292	intact-crc:6440C59F7F038633|rigid:/hmm1xVCnVzWSAVYiTg4jul4030	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9NWX6	uniprotkb:P08458	intact:EBI-746510|uniprotkb:Q53G12|uniprotkb:Q7L5R3|uniprotkb:Q9H0S2|uniprotkb:D3DQJ5|ensembl:ENSP00000231198	intact:EBI-17889|uniprotkb:D6VTE3|ensemblfungi:YDR523C	psi-mi:thg1_human(display_long)|uniprotkb:Induced in high glucose-1(gene name synonym)|uniprotkb:tRNA-histidine guanylyltransferase(gene name synonym)|uniprotkb:Interphase cytoplasmic foci protein 45(gene name synonym)|uniprotkb:THG1L(gene name)|psi-mi:THG1L(display_short)|uniprotkb:ICF45(gene name synonym)	psi-mi:sps1_yeast(display_long)|uniprotkb:D9719.27(orf name)|uniprotkb:YDR523C(locus name)|uniprotkb:SPS1(gene name)|psi-mi:SPS1(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11523051|imex:IM-24995-82	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001304753.1|refseq:NP_001304754.1|refseq:NP_001304755.1|refseq:NP_060342.2|ensembl:ENSG00000113272(gene)|ensembl:ENST00000231198(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006400"(tRNA modification)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008033"(tRNA processing)|go:"GO:0008053"(mitochondrial fusion)|go:"GO:0008193"(tRNA guanylyltransferase activity)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0051289"(protein homotetramerization)|go:"GO:1990046"(stress-induced mitochondrial fusion)|go:"GO:1990234"(transferase complex)|interpro:IPR007537(tRNAHis guanylyltransferase)|interpro:IPR024956|interpro:IPR025845|interpro:IPR038469|rcsb pdb:3OTB|rcsb pdb:3OTC|rcsb pdb:3OTD|rcsb pdb:3OTE|rcsb pdb:7CV1|reactome:R-HSA-6782315|dip:DIP-59479N|entrezgene/locuslink:54974(identity)	refseq:NP_010811.1|sgd:S000002931|ensemblfungi:YDR523C(gene)|ensemblfungi:YDR523C_mRNA(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005628"(prospore membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0030437"(ascospore formation)|go:"GO:0030476"(ascospore wall assembly)|go:"GO:0051229"(meiotic spindle disassembly)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903024"(positive regulation of ascospore-type prospore membrane formation)|go:"GO:1904750"(negative regulation of protein localization to nucleolus)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|dip:DIP-6598N|mint:P08458|sgd:YDR523C(identity)	-	-	crc64:6143055E85BAF4FF	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:P1Q3muoqX06qZw9Xu0Gz5f8ALv49606	rogid:icg6ZPlLWE0X6aii9Onq9FVzOuM559292	intact-crc:14AC34DB630140D9|rigid:SrDa8HKNeMAkeD8LtzmHv59JIFQ	false	sufficient binding region:30-298	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9NZL4	uniprotkb:P09435	intact:EBI-356763|uniprotkb:O95351|uniprotkb:Q6ZNU5|uniprotkb:B3KQP0|uniprotkb:B4DG11|ensembl:ENSP00000255631|ensembl:ENSP00000398244|ensembl:ENSP00000467574	intact:EBI-8611|uniprotkb:P18862|uniprotkb:D6VPS7|ensemblfungi:YBL075C	psi-mi:hpbp1_human(display_long)|uniprotkb:HSPBP1(gene name)|psi-mi:HSPBP1(display_short)|uniprotkb:HSPBP(gene name synonym)|uniprotkb:PP1845(orf name)|uniprotkb:Heat shock protein-binding protein 1(gene name synonym)|uniprotkb:Hsp70-interacting protein 1(gene name synonym)|uniprotkb:Hsp70-binding protein 2(gene name synonym)|uniprotkb:Hsp70-interacting protein 2(gene name synonym)	psi-mi:hsp73_yeast(display_long)|uniprotkb:YBL06.07(orf name)|uniprotkb:YBL0610(orf name)|uniprotkb:YBL075C(locus name)|uniprotkb:SSA3(gene name)|psi-mi:SSA3(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11523071|imex:IM-24995-84	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001123578.1|refseq:NP_036399.3|ensembl:ENSG00000133265(gene)|ensembl:ENST00000255631(transcript)|ensembl:ENST00000433386(transcript)|ensembl:ENST00000587922(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006457"(protein folding)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013918(Nucleotide exchange factor Fes1)|interpro:IPR016024(Armadillo-type fold)|mint:Q9NZL4|rcsb pdb:1XQR|rcsb pdb:1XQS|refseq:NP_001284529.1|refseq:XP_016882033.1|entrezgene/locuslink:23640(identity)	refseq:NP_009478.1|sgd:S000000171|mint:P09435|dip:DIP-2266N|ensemblfungi:YBL075C(gene)|ensemblfungi:YBL075C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|sgd:YBL075C(identity)	-	-	crc64:F4B136759B7D4636	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2018/09/18	rogid:26Au2GesO5ysT/yhYX/0oOO9Md89606	rogid:u3ayjvFHnVNMMrDZdrB7NWaGzBg559292	intact-crc:589D9AAE9FE8AEF3|rigid:dUh2qq010WSAE0IUFY/aCrP3YqM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q15038	uniprotkb:P0CH08	intact:EBI-724310|ensembl:ENSP00000394699|uniprotkb:E9PB45|uniprotkb:A8K254|uniprotkb:B4DDT5|uniprotkb:C9JA96|uniprotkb:C9JP84|uniprotkb:B4E1G3|uniprotkb:F8VU62	intact:EBI-11523108|uniprotkb:D6VVD9|uniprotkb:P04838|uniprotkb:P14796|uniprotkb:P61864|uniprotkb:Q6LA96|ensemblfungi:YIL148W|ensemblfungi:YKR094C	psi-mi:dazp2_human(display_long)|uniprotkb:Deleted in azoospermia-associated protein 2(gene name synonym)|uniprotkb:DAZAP2(gene name)|psi-mi:DAZAP2(display_short)|uniprotkb:KIAA0058(gene name synonym)	psi-mi:rl40a_yeast(display_long)|uniprotkb:RPL40A(gene name)|psi-mi:RPL40A(display_short)|uniprotkb:UBI1(gene name synonym)|uniprotkb:YIL148W(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11523130|imex:IM-24995-89	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000183283(gene)|ensembl:ENST00000412716(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0016607"(nuclear speck)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0050699"(WW domain binding)|interpro:IPR022730|mint:Q15038|refseq:NP_001129736.1|refseq:NP_055579.1|ensembl:ENSP00000394699|ensembl:ENST00000425012|ensembl:ENSP00000408251|ensembl:ENST00000439799|ensembl:ENSP00000398804|ensembl:ENST00000449723|ensembl:ENSP00000412812|ensembl:ENST00000549555|ensembl:ENSP00000448051|ensembl:ENST00000549732|ensembl:ENSP00000446554|refseq:NP_001129741.1|refseq:NP_001129739.1|refseq:NP_001129740.1|refseq:NP_001129738.1|entrezgene/locuslink:9802(identity)	rcsb pdb:5NDG|rcsb pdb:5NDV|rcsb pdb:5NDW|rcsb pdb:5OBM|rcsb pdb:6WOO|interpro:IPR000626(Ubiquitin)|interpro:IPR001975(Ribosomal protein L40e)|interpro:IPR019954|interpro:IPR019956|interpro:IPR029071|rcsb pdb:3J6X|rcsb pdb:3J6Y|rcsb pdb:3J77|rcsb pdb:3J78|rcsb pdb:4U3M|rcsb pdb:4U3N|rcsb pdb:4U3U|rcsb pdb:4U4N|rcsb pdb:4U4O|rcsb pdb:4U4Q|rcsb pdb:4U4R|rcsb pdb:4U4U|rcsb pdb:4U4Y|rcsb pdb:4U4Z|rcsb pdb:4U50|rcsb pdb:4U51|rcsb pdb:4U52|rcsb pdb:4U53|rcsb pdb:4U55|rcsb pdb:4U56|rcsb pdb:4U6F|rcsb pdb:4V6I|rcsb pdb:4V88|rcsb pdb:4V8T|rcsb pdb:4V8Y|rcsb pdb:4V8Z|rcsb pdb:5APN|rcsb pdb:5APO|refseq:NP_012118.1|refseq:NP_013020.3|sgd:S000001410|rcsb pdb:6TB3|rcsb pdb:6TNU|rcsb pdb:5DGE|rcsb pdb:5M1J|rcsb pdb:5MC6|rcsb pdb:5TGM|rcsb pdb:6EF3|rcsb pdb:6OIG|rcsb pdb:6OA9|rcsb pdb:6OAA|rcsb pdb:6QIK|rcsb pdb:6QT0|rcsb pdb:6QTZ|rcsb pdb:6R84|rcsb pdb:6R87|rcsb pdb:6RI5|rcsb pdb:5FCI|rcsb pdb:5FCJ|rcsb pdb:5DGF|rcsb pdb:5DGV|rcsb pdb:5LYB|rcsb pdb:5TGA|rcsb pdb:6HHQ|rcsb pdb:5DC3|rcsb pdb:5I4L|rcsb pdb:6N8M|rcsb pdb:6N8N|rcsb pdb:6N8O|rcsb pdb:6I7O|rcsb pdb:7AZY|rcsb pdb:7B7D|rcsb pdb:7NRC|rcsb pdb:7NRD|reactome:R-SCE-1169408|reactome:R-SCE-5656169|rcsb pdb:5GAK|rcsb pdb:6Q8Y|ensemblfungi:YIL148W(gene)|ensemblfungi:YIL148W_mRNA(transcript)|ensemblfungi:YKR094C(gene)|ensemblfungi:YKR094C_mRNA(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0031386"(protein tag)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042254"(ribosome biogenesis)|rcsb pdb:6HD7|rcsb pdb:5ON6|rcsb pdb:5DAT|rcsb pdb:5JUO|rcsb pdb:5JUP|rcsb pdb:5JUS|rcsb pdb:5JUT|rcsb pdb:5JUU|rcsb pdb:5T62|rcsb pdb:5T6R|interpro:IPR038587|rcsb pdb:5MEI|rcsb pdb:5TBW|rcsb pdb:6GQ1|rcsb pdb:6GQB|rcsb pdb:6GQV|rcsb pdb:6R86|rcsb pdb:6S47|rcsb pdb:6NYO|rcsb pdb:6T4Q|rcsb pdb:6T7I|rcsb pdb:6T7T|rcsb pdb:6T83|rcsb pdb:6SNT|rcsb pdb:6SV4|rcsb pdb:6XIQ|rcsb pdb:6Z6J|rcsb pdb:6Z6K|sgd:YKR094C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/03/16	rogid:ASRqCZBG4q1U/y95PUSMKsgfm/g9606	rogid:6+5uVAktIpS9HyPHQ6BzXEuT/y0559292	intact-crc:F57313B39EA21166|rigid:Lh/mIxvSJnpc6qjoQ5u0j8lqgrA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q13137	uniprotkb:P0CH08	intact:EBI-739580|uniprotkb:B4DDC4|uniprotkb:E7ENK0|uniprotkb:Q53FQ5|uniprotkb:Q53HB5|uniprotkb:Q6IBN9|uniprotkb:Q9BTF7|uniprotkb:B2RBT0|ensembl:ENSP00000258947|uniprotkb:B4E0C0|uniprotkb:E7ETP5|uniprotkb:B4DDT4|uniprotkb:B4DP36|uniprotkb:E9PBE5	intact:EBI-11523108|uniprotkb:D6VVD9|uniprotkb:P04838|uniprotkb:P14796|uniprotkb:P61864|uniprotkb:Q6LA96|ensemblfungi:YIL148W|ensemblfungi:YKR094C	psi-mi:caco2_human(display_long)|uniprotkb:CALCOCO2(gene name)|psi-mi:CALCOCO2(display_short)|uniprotkb:NDP52(gene name synonym)|uniprotkb:Nuclear domain 10 protein NDP52(gene name synonym)|uniprotkb:Antigen nuclear dot 52 kDa protein(gene name synonym)|uniprotkb:Nuclear dot protein 52(gene name synonym)	psi-mi:rl40a_yeast(display_long)|uniprotkb:RPL40A(gene name)|psi-mi:RPL40A(display_short)|uniprotkb:UBI1(gene name synonym)|uniprotkb:YIL148W(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11523121|imex:IM-24995-88	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001248319.1|refseq:NP_001248320.1|refseq:NP_001248322.1|refseq:NP_005822.1|ensembl:ENSG00000136436(gene)|ensembl:ENST00000258947(transcript)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016032"(viral process)|go:"GO:0016605"(PML body)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0098792"(xenophagy)|go:"GO:1901098"(positive regulation of autophagosome maturation)|interpro:IPR041611|interpro:IPR041641|mint:Q13137|rcsb pdb:2MXP|rcsb pdb:3VVV|rcsb pdb:3VVW|rcsb pdb:4GXL|rcsb pdb:4HAN|rcsb pdb:4XKL|rcsb pdb:5AAQ|rcsb pdb:5Z7A|rcsb pdb:5Z7L|refseq:NP_001248324.1|dip:DIP-57534N|entrezgene/locuslink:10241(identity)	rcsb pdb:5NDG|rcsb pdb:5NDV|rcsb pdb:5NDW|rcsb pdb:5OBM|rcsb pdb:6WOO|interpro:IPR000626(Ubiquitin)|interpro:IPR001975(Ribosomal protein L40e)|interpro:IPR019954|interpro:IPR019956|interpro:IPR029071|rcsb pdb:3J6X|rcsb pdb:3J6Y|rcsb pdb:3J77|rcsb pdb:3J78|rcsb pdb:4U3M|rcsb pdb:4U3N|rcsb pdb:4U3U|rcsb pdb:4U4N|rcsb pdb:4U4O|rcsb pdb:4U4Q|rcsb pdb:4U4R|rcsb pdb:4U4U|rcsb pdb:4U4Y|rcsb pdb:4U4Z|rcsb pdb:4U50|rcsb pdb:4U51|rcsb pdb:4U52|rcsb pdb:4U53|rcsb pdb:4U55|rcsb pdb:4U56|rcsb pdb:4U6F|rcsb pdb:4V6I|rcsb pdb:4V88|rcsb pdb:4V8T|rcsb pdb:4V8Y|rcsb pdb:4V8Z|rcsb pdb:5APN|rcsb pdb:5APO|refseq:NP_012118.1|refseq:NP_013020.3|sgd:S000001410|rcsb pdb:6TB3|rcsb pdb:6TNU|rcsb pdb:5DGE|rcsb pdb:5M1J|rcsb pdb:5MC6|rcsb pdb:5TGM|rcsb pdb:6EF3|rcsb pdb:6OIG|rcsb pdb:6OA9|rcsb pdb:6OAA|rcsb pdb:6QIK|rcsb pdb:6QT0|rcsb pdb:6QTZ|rcsb pdb:6R84|rcsb pdb:6R87|rcsb pdb:6RI5|rcsb pdb:5FCI|rcsb pdb:5FCJ|rcsb pdb:5DGF|rcsb pdb:5DGV|rcsb pdb:5LYB|rcsb pdb:5TGA|rcsb pdb:6HHQ|rcsb pdb:5DC3|rcsb pdb:5I4L|rcsb pdb:6N8M|rcsb pdb:6N8N|rcsb pdb:6N8O|rcsb pdb:6I7O|rcsb pdb:7AZY|rcsb pdb:7B7D|rcsb pdb:7NRC|rcsb pdb:7NRD|reactome:R-SCE-1169408|reactome:R-SCE-5656169|rcsb pdb:5GAK|rcsb pdb:6Q8Y|ensemblfungi:YIL148W(gene)|ensemblfungi:YIL148W_mRNA(transcript)|ensemblfungi:YKR094C(gene)|ensemblfungi:YKR094C_mRNA(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0031386"(protein tag)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042254"(ribosome biogenesis)|rcsb pdb:6HD7|rcsb pdb:5ON6|rcsb pdb:5DAT|rcsb pdb:5JUO|rcsb pdb:5JUP|rcsb pdb:5JUS|rcsb pdb:5JUT|rcsb pdb:5JUU|rcsb pdb:5T62|rcsb pdb:5T6R|interpro:IPR038587|rcsb pdb:5MEI|rcsb pdb:5TBW|rcsb pdb:6GQ1|rcsb pdb:6GQB|rcsb pdb:6GQV|rcsb pdb:6R86|rcsb pdb:6S47|rcsb pdb:6NYO|rcsb pdb:6T4Q|rcsb pdb:6T7I|rcsb pdb:6T7T|rcsb pdb:6T83|rcsb pdb:6SNT|rcsb pdb:6SV4|rcsb pdb:6XIQ|rcsb pdb:6Z6J|rcsb pdb:6Z6K|sgd:YKR094C(identity)	-	crc64:609B121DA1A9DCB8	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/03/16	rogid:N/GPJUGBK+Dh5Cg+csmafphuo9M9606	rogid:6+5uVAktIpS9HyPHQ6BzXEuT/y0559292	intact-crc:BBDE5AB3094989E1|rigid:5MdELz9eh+rq5yMhwoRRG8yaiP4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P0CH08	uniprotkb:E9PFK9	intact:EBI-11523108|uniprotkb:D6VVD9|uniprotkb:P04838|uniprotkb:P14796|uniprotkb:P61864|uniprotkb:Q6LA96|ensemblfungi:YIL148W|ensemblfungi:YKR094C	intact:EBI-11523104|ensembl:ENSP00000403429	psi-mi:rl40a_yeast(display_long)|uniprotkb:RPL40A(gene name)|psi-mi:RPL40A(display_short)|uniprotkb:UBI1(gene name synonym)|uniprotkb:YIL148W(locus name)	psi-mi:e9pfk9_human(display_long)|uniprotkb:RABGEF1(gene name)|psi-mi:RABGEF1(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11523110|imex:IM-24995-87	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:5NDG|rcsb pdb:5NDV|rcsb pdb:5NDW|rcsb pdb:5OBM|rcsb pdb:6WOO|interpro:IPR000626(Ubiquitin)|interpro:IPR001975(Ribosomal protein L40e)|interpro:IPR019954|interpro:IPR019956|interpro:IPR029071|rcsb pdb:3J6X|rcsb pdb:3J6Y|rcsb pdb:3J77|rcsb pdb:3J78|rcsb pdb:4U3M|rcsb pdb:4U3N|rcsb pdb:4U3U|rcsb pdb:4U4N|rcsb pdb:4U4O|rcsb pdb:4U4Q|rcsb pdb:4U4R|rcsb pdb:4U4U|rcsb pdb:4U4Y|rcsb pdb:4U4Z|rcsb pdb:4U50|rcsb pdb:4U51|rcsb pdb:4U52|rcsb pdb:4U53|rcsb pdb:4U55|rcsb pdb:4U56|rcsb pdb:4U6F|rcsb pdb:4V6I|rcsb pdb:4V88|rcsb pdb:4V8T|rcsb pdb:4V8Y|rcsb pdb:4V8Z|rcsb pdb:5APN|rcsb pdb:5APO|refseq:NP_012118.1|refseq:NP_013020.3|sgd:S000001410|rcsb pdb:6TB3|rcsb pdb:6TNU|rcsb pdb:5DGE|rcsb pdb:5M1J|rcsb pdb:5MC6|rcsb pdb:5TGM|rcsb pdb:6EF3|rcsb pdb:6OIG|rcsb pdb:6OA9|rcsb pdb:6OAA|rcsb pdb:6QIK|rcsb pdb:6QT0|rcsb pdb:6QTZ|rcsb pdb:6R84|rcsb pdb:6R87|rcsb pdb:6RI5|rcsb pdb:5FCI|rcsb pdb:5FCJ|rcsb pdb:5DGF|rcsb pdb:5DGV|rcsb pdb:5LYB|rcsb pdb:5TGA|rcsb pdb:6HHQ|rcsb pdb:5DC3|rcsb pdb:5I4L|rcsb pdb:6N8M|rcsb pdb:6N8N|rcsb pdb:6N8O|rcsb pdb:6I7O|rcsb pdb:7AZY|rcsb pdb:7B7D|rcsb pdb:7NRC|rcsb pdb:7NRD|reactome:R-SCE-1169408|reactome:R-SCE-5656169|rcsb pdb:5GAK|rcsb pdb:6Q8Y|ensemblfungi:YIL148W(gene)|ensemblfungi:YIL148W_mRNA(transcript)|ensemblfungi:YKR094C(gene)|ensemblfungi:YKR094C_mRNA(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0031386"(protein tag)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042254"(ribosome biogenesis)|rcsb pdb:6HD7|rcsb pdb:5ON6|rcsb pdb:5DAT|rcsb pdb:5JUO|rcsb pdb:5JUP|rcsb pdb:5JUS|rcsb pdb:5JUT|rcsb pdb:5JUU|rcsb pdb:5T62|rcsb pdb:5T6R|interpro:IPR038587|rcsb pdb:5MEI|rcsb pdb:5TBW|rcsb pdb:6GQ1|rcsb pdb:6GQB|rcsb pdb:6GQV|rcsb pdb:6R86|rcsb pdb:6S47|rcsb pdb:6NYO|rcsb pdb:6T4Q|rcsb pdb:6T7I|rcsb pdb:6T7T|rcsb pdb:6T83|rcsb pdb:6SNT|rcsb pdb:6SV4|rcsb pdb:6XIQ|rcsb pdb:6Z6J|rcsb pdb:6Z6K|sgd:YKR094C(identity)	ensembl:ENSG00000154710(gene)|ensembl:ENST00000439720(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|interpro:IPR002653(Zinc finger, A20-type)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR037191|interpro:IPR041545|entrezgene/locuslink:27342(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/03/16	rogid:6+5uVAktIpS9HyPHQ6BzXEuT/y0559292	rogid:JDHW8cuCB2z39j6a+LlkARnLfYo9606	intact-crc:D96AE3D280883941|rigid:Wx9NGINsPfl18eLv0ZOa7FGIPRA	false	-	sufficient binding region:14-504	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P10507	uniprotkb:Q8WTU0	intact:EBI-11212|uniprotkb:D6VYG9|ensemblfungi:YLR163C	intact:EBI-748248|uniprotkb:Q7Z4U6|uniprotkb:Q8WTS3|ensembl:ENSP00000302805	psi-mi:mppb_yeast(display_long)|uniprotkb:MAS1(gene name)|psi-mi:MAS1(display_short)|uniprotkb:MIF1(gene name synonym)|uniprotkb:Beta-MPP(gene name synonym)|uniprotkb:Mitochondrial assembly protein 1(gene name synonym)|uniprotkb:Processing enhancing protein(gene name synonym)|uniprotkb:L9632.10(orf name)|uniprotkb:YLR163C(locus name)	psi-mi:ddi1_human(display_long)|uniprotkb:DDI1(gene name)|psi-mi:DDI1(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11523139|imex:IM-24995-90	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:1HR8|rcsb pdb:1HR9|reactome:R-SCE-611105|ensemblfungi:YLR163C_mRNA(transcript)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006627"(protein processing involved in protein targeting to mitochondrion)|go:"GO:0017087"(mitochondrial processing peptidase complex)|go:"GO:0046872"(metal ion binding)|interpro:IPR001431(Peptidase M16, zinc-binding site)|interpro:IPR007863(Peptidase M16, C-terminal)|interpro:IPR011249(Metalloenzyme, LuxS/M16 peptidase-like, metal-binding)|interpro:IPR011765(Peptidase M16, N-terminal)|rcsb pdb:1HR6|rcsb pdb:1HR7|ensemblfungi:YLR163C(gene)|refseq:NP_013264.1|sgd:S000004153|mint:P10507|dip:DIP-2402N|sgd:YLR163C(identity)	refseq:NP_001001711.1|interpro:IPR000626(Ubiquitin)|interpro:IPR019103|interpro:IPR021109|interpro:IPR029071|interpro:IPR033882|rcsb pdb:3S8I|go:"GO:0097752"(regulation of DNA stability)|ensembl:ENSG00000170967(gene)|ensembl:ENST00000302259(transcript)|go:"GO:0004190"(aspartic-type endopeptidase activity)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0072711"(cellular response to hydroxyurea)|dip:DIP-60626N|entrezgene/locuslink:414301(identity)	-	crc64:084CE63C495EDFC4	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:VwOYuBlWEvXC631d5WAhOhjVAPc559292	rogid:000xGRvL5rBRHv7/sbuzB7i7Wtc9606	intact-crc:2567AF6D11CC8F2C|rigid:jpx1gdbg9ahPZ4bWDn5eNL6p70k	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P31153	uniprotkb:P10659	intact:EBI-1050743|uniprotkb:Q53SP5|uniprotkb:A8K511|uniprotkb:D6W5L1|ensembl:ENSP00000303147|uniprotkb:B4DN45	intact:EBI-10789|ensemblfungi:YLR180W|uniprotkb:D6VYI4	psi-mi:metk2_human(display_long)|uniprotkb:Methionine adenosyltransferase 2(gene name synonym)|uniprotkb:Methionine adenosyltransferase II(gene name synonym)|uniprotkb:MAT2A(gene name)|psi-mi:MAT2A(display_short)|uniprotkb:AMS2(gene name synonym)|uniprotkb:MATA2(gene name synonym)	psi-mi:metk1_yeast(display_long)|uniprotkb:SAM1(gene name)|psi-mi:SAM1(display_short)|uniprotkb:ETH10(gene name synonym)|uniprotkb:YLR180W(locus name)|uniprotkb:L9470.9(orf name)|uniprotkb:Methionine adenosyltransferase 1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11523157|imex:IM-24995-92	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005902.1|rcsb pdb:5A1G|rcsb pdb:5A1I|rcsb pdb:5UGH|rcsb pdb:6FAJ|rcsb pdb:6FBN|rcsb pdb:6FBO|rcsb pdb:6FBP|rcsb pdb:6FCB|rcsb pdb:6FCD|rcsb pdb:6FWB|ensembl:ENSG00000168906(gene)|ensembl:ENST00000306434(transcript)|go:"GO:0004478"(methionine adenosyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006556"(S-adenosylmethionine biosynthetic process)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0034214"(protein hexamerization)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048269"(methionine adenosyltransferase complex)|go:"GO:0051291"(protein heterooligomerization)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR002133(S-adenosylmethionine synthetase)|rcsb pdb:6G6R|rcsb pdb:6P9V|rcsb pdb:6WKB|interpro:IPR022628|rcsb pdb:7BHR|rcsb pdb:7BHS|interpro:IPR022629|interpro:IPR022630|interpro:IPR022631|interpro:IPR022636|mint:P31153|rcsb pdb:2P02|rcsb pdb:4KTT|rcsb pdb:4KTV|rcsb pdb:4NDN|rcsb pdb:5A19|rcsb pdb:7BHT|rcsb pdb:7BHU|rcsb pdb:7BHV|rcsb pdb:7BHW|rcsb pdb:7BHX|rcsb pdb:7KCC|rcsb pdb:7KCE|rcsb pdb:7KCF|rcsb pdb:7KDA|rcsb pdb:7KDB|rcsb pdb:7L1A|reactome:R-HSA-156581|entrezgene/locuslink:4144(identity)	ensemblfungi:YLR180W(gene)|ensemblfungi:YLR180W_mRNA(transcript)|go:"GO:0004478"(methionine adenosyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006555"(methionine metabolic process)|go:"GO:0006556"(S-adenosylmethionine biosynthetic process)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0046872"(metal ion binding)|interpro:IPR002133(S-adenosylmethionine synthetase)|interpro:IPR022628|interpro:IPR022629|interpro:IPR022630|interpro:IPR022631|interpro:IPR022636|reactome:R-SCE-156581|reactome:R-SCE-1614635|reactome:R-SCE-2408508|refseq:NP_013281.1|sgd:S000004170|mint:P10659|dip:DIP-6667N|sgd:YLR180W(identity)	-	-	crc64:18F82FC809EE4706	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:8QDKkbuHcvQtfzy2XkVjCKjTK709606	rogid:PmIeDsMIksGSxihwmK1DqLFOItc559292	intact-crc:4308D58AB906514E|rigid:CosvTDA0SKTdkrPi4EY0Y/z7Dm0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P10507	uniprotkb:Q96IK5	intact:EBI-11212|uniprotkb:D6VYG9|ensemblfungi:YLR163C	intact:EBI-2548508|ensembl:ENSP00000282570|uniprotkb:Q9H826|uniprotkb:Q9H8V7|uniprotkb:Q9H927	psi-mi:mppb_yeast(display_long)|uniprotkb:MAS1(gene name)|psi-mi:MAS1(display_short)|uniprotkb:MIF1(gene name synonym)|uniprotkb:Beta-MPP(gene name synonym)|uniprotkb:Mitochondrial assembly protein 1(gene name synonym)|uniprotkb:Processing enhancing protein(gene name synonym)|uniprotkb:L9632.10(orf name)|uniprotkb:YLR163C(locus name)	psi-mi:gmcl1_human(display_long)|uniprotkb:GMCL1(gene name)|psi-mi:GMCL1(display_short)|uniprotkb:GCL(gene name synonym)|uniprotkb:BTBD13(gene name synonym)|uniprotkb:SPATA29(gene name synonym)|uniprotkb:Spermatogenesis-associated protein 29(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11523148|imex:IM-24995-91	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:1HR8|rcsb pdb:1HR9|reactome:R-SCE-611105|ensemblfungi:YLR163C_mRNA(transcript)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006627"(protein processing involved in protein targeting to mitochondrion)|go:"GO:0017087"(mitochondrial processing peptidase complex)|go:"GO:0046872"(metal ion binding)|interpro:IPR001431(Peptidase M16, zinc-binding site)|interpro:IPR007863(Peptidase M16, C-terminal)|interpro:IPR011249(Metalloenzyme, LuxS/M16 peptidase-like, metal-binding)|interpro:IPR011765(Peptidase M16, N-terminal)|rcsb pdb:1HR6|rcsb pdb:1HR7|ensemblfungi:YLR163C(gene)|refseq:NP_013264.1|sgd:S000004153|mint:P10507|dip:DIP-2402N|sgd:YLR163C(identity)	ensembl:ENSG00000087338(gene)|ensembl:ENST00000282570(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0007281"(germ cell development)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016363"(nuclear matrix)|go:"GO:0042802"(identical protein binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR043380|refseq:NP_848526.1|entrezgene/locuslink:64395(identity)	-	crc64:084CE63C495EDFC4	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:VwOYuBlWEvXC631d5WAhOhjVAPc559292	rogid:ED8yqySVu7BWxpw3DUSNBZSQWrk9606	intact-crc:DA13C8720C6582C1|rigid:kUmOXYm7g25dCm8NYfT0YIStVMA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q02818	uniprotkb:P10823	intact:EBI-2622179|uniprotkb:Q7Z4J7|uniprotkb:B2RD64|uniprotkb:Q9BUR1|uniprotkb:Q15838|intact:EBI-28978015|ensembl:ENSP00000385211|ensembl:ENSP00000385923	intact:EBI-7382|uniprotkb:D3DLR9|ensemblfungi:YER020W	psi-mi:nucb1_human(display_long)|uniprotkb:NUC(gene name synonym)|uniprotkb:CALNUC(gene name synonym)|uniprotkb:NUCB1(gene name)|psi-mi:NUCB1(display_short)	psi-mi:gpa2_yeast(display_long)|uniprotkb:YER020W(locus name)|uniprotkb:GPA2(gene name)|psi-mi:GPA2(display_short)|uniprotkb:SSP101(gene name synonym)|uniprotkb:GP2-alpha(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11523166|imex:IM-24995-93	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000385923|ensembl:ENSP00000385211|refseq:NP_006175.2|refseq:XP_016882334.1|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072718"(response to cisplatin)|go:"GO:0090498"(extrinsic component of Golgi membrane)|go:"GO:0098547"(lumenal side of Golgi membrane)|go:"GO:1903533"(regulation of protein targeting)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR040250|interpro:IPR040253|mint:Q02818|rcsb pdb:1SNL|reactome:R-HSA-381426|reactome:R-HSA-8957275|ensembl:ENSG00000104805(gene)|ensembl:ENST00000405315(transcript)|ensembl:ENST00000407032(transcript)|go:"GO:0001965"(G-protein alpha-subunit binding)|go:"GO:0003677"(DNA binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005769"(early endosome)|entrezgene/locuslink:4924(identity)	sgd:S000000822|refseq:NP_010937.3|mint:P10823|dip:DIP-4346N|ensemblfungi:YER020W(gene)|ensemblfungi:YER020W_mRNA(transcript)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0007165"(signal transduction)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0008361"(regulation of cell size)|go:"GO:0009757"(hexose mediated signaling)|go:"GO:0010255"(glucose mediated signaling pathway)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0030437"(ascospore formation)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR002975(Fungal G-protein, alpha subunit)|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|reactome:R-SCE-112043|reactome:R-SCE-202040|reactome:R-SCE-399997|reactome:R-SCE-416476|reactome:R-SCE-416482|reactome:R-SCE-418592|reactome:R-SCE-434316|reactome:R-SCE-9013148|sgd:YER020W(identity)	-	-	crc64:881B91792AE91748	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:exoVYPq5+NxEpgkm/gAQay/Uwuk9606	rogid:ujQYVD/yCqR8/T2eRPygiuTD7Jg559292	intact-crc:22C3698DA8C9D582|rigid:KhM6hQ81nDdyd4SpwilDV4QHX/A	false	sufficient binding region:286-461	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P12612	uniprotkb:P23497-2	intact:EBI-19045|uniprotkb:D6VSJ6|ensemblfungi:YDR212W	intact:EBI-6589365|ensembl:ENSP00000386404	psi-mi:tcpa_yeast(display_long)|uniprotkb:TCP1(gene name)|psi-mi:TCP1(display_short)|uniprotkb:CCT1(gene name synonym)|uniprotkb:YDR212W(locus name)|uniprotkb:YD8142.13(orf name)|uniprotkb:YD8142B.04(orf name)|uniprotkb:CCT-alpha(gene name synonym)	psi-mi:p23497-2(display_long)|uniprotkb:SP100(isoform synonym)|uniprotkb:SP100(gene name)|psi-mi:SP100(display_short)|uniprotkb:Nuclear dot-associated Sp100 protein(gene name synonym)|uniprotkb:Speckled 100 kDa(gene name synonym)|uniprotkb:SP100A(isoform synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11523228|imex:IM-24995-99	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010498.1|sgd:S000002620|ensemblfungi:YDR212W(gene)|ensemblfungi:YDR212W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012715(T-complex protein 1, alpha subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|rcsb pdb:4V81|rcsb pdb:4V8R|rcsb pdb:4V94|rcsb pdb:5GW4|rcsb pdb:5GW5|rcsb pdb:6KRD|rcsb pdb:6KRE|rcsb pdb:6KS6|rcsb pdb:6KS7|rcsb pdb:6KS8|reactome:R-SCE-390471|reactome:R-SCE-6814122|dip:DIP-2965N|mint:P12612|sgd:YDR212W(identity)	intact:EBI-751145(isoform-parent)|uniprotkb:P23497-2(isoform-parent)|ensembl:ENSG00000067066(gene)|ensembl:ENST00000409341(transcript)|entrezgene/locuslink:6672(identity)	-	crc64:02C625D329359E61	isoform-comment:Major isoform.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:xWMsvY106Y6yQ54SOif2UlScafM559292	rogid:HrcogLANB///4vkSYtZ7OtzOb2k9606	intact-crc:8B1A9DD61EA5D7E0|rigid:b276Sfs8Vc0EZEcpKKwu77YIemc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P12612	uniprotkb:O60232	intact:EBI-19045|uniprotkb:D6VSJ6|ensemblfungi:YDR212W	intact:EBI-741415|ensembl:ENSP00000312318	psi-mi:tcpa_yeast(display_long)|uniprotkb:TCP1(gene name)|psi-mi:TCP1(display_short)|uniprotkb:CCT1(gene name synonym)|uniprotkb:YDR212W(locus name)|uniprotkb:YD8142.13(orf name)|uniprotkb:YD8142B.04(orf name)|uniprotkb:CCT-alpha(gene name synonym)	psi-mi:znrd2_human(display_long)|uniprotkb:ZNRD2(gene name)|psi-mi:ZNRD2(display_short)|uniprotkb:Autoantigen p27(gene name synonym)|uniprotkb:SSSCA1(gene name synonym)|uniprotkb:Sjoegren syndrome/scleroderma autoantigen 1(gene name synonym)|uniprotkb:Zinc ribbon domain-containing protein 2(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11523219|imex:IM-24995-98	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010498.1|sgd:S000002620|ensemblfungi:YDR212W(gene)|ensemblfungi:YDR212W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012715(T-complex protein 1, alpha subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|rcsb pdb:4V81|rcsb pdb:4V8R|rcsb pdb:4V94|rcsb pdb:5GW4|rcsb pdb:5GW5|rcsb pdb:6KRD|rcsb pdb:6KRE|rcsb pdb:6KS6|rcsb pdb:6KS7|rcsb pdb:6KS8|reactome:R-SCE-390471|reactome:R-SCE-6814122|dip:DIP-2965N|mint:P12612|sgd:YDR212W(identity)	refseq:NP_006387.1|ensembl:ENSG00000173465(gene)|ensembl:ENST00000309328(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0051301"(cell division)|interpro:IPR009563(Sjogrens syndrome scleroderma autoantigen 1)|rcsb pdb:6HCZ|entrezgene/locuslink:10534(identity)	-	crc64:02C625D329359E61	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:xWMsvY106Y6yQ54SOif2UlScafM559292	rogid:Uou80pZneoL39/0YYzb1TAbiB2I9606	intact-crc:7DAA7BAACC3CD30C|rigid://TjGLfHSuH0wACVj1nKRpTLARQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P10823	uniprotkb:Q9GZZ9	intact:EBI-7382|uniprotkb:D3DLR9|ensemblfungi:YER020W	intact:EBI-747805|uniprotkb:A6NJL3|uniprotkb:Q96ST1|uniprotkb:D3DNC8|ensembl:ENSP00000348565	psi-mi:gpa2_yeast(display_long)|uniprotkb:YER020W(locus name)|uniprotkb:GPA2(gene name)|psi-mi:GPA2(display_short)|uniprotkb:SSP101(gene name synonym)|uniprotkb:GP2-alpha(gene name synonym)	psi-mi:uba5_human(display_long)|uniprotkb:Ubiquitin-activating enzyme E1 domain-containing protein 1(gene name synonym)|uniprotkb:UFM1-activating enzyme(gene name synonym)|uniprotkb:ThiFP1(gene name synonym)|uniprotkb:UBA5(gene name)|psi-mi:UBA5(display_short)|uniprotkb:UBE1DC1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11523177|imex:IM-24995-94	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000000822|refseq:NP_010937.3|mint:P10823|dip:DIP-4346N|ensemblfungi:YER020W(gene)|ensemblfungi:YER020W_mRNA(transcript)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0007165"(signal transduction)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0008361"(regulation of cell size)|go:"GO:0009757"(hexose mediated signaling)|go:"GO:0010255"(glucose mediated signaling pathway)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0030437"(ascospore formation)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR002975(Fungal G-protein, alpha subunit)|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|reactome:R-SCE-112043|reactome:R-SCE-202040|reactome:R-SCE-399997|reactome:R-SCE-416476|reactome:R-SCE-416482|reactome:R-SCE-418592|reactome:R-SCE-434316|reactome:R-SCE-9013148|sgd:YER020W(identity)	refseq:NP_079094.1|refseq:NP_938143.1|refseq:NP_001307139.1|refseq:NP_001308167.1|refseq:NP_001308168.1|ensembl:ENSG00000081307(gene)|ensembl:ENST00000356232(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030219"(megakaryocyte differentiation)|go:"GO:0032446"(protein modification by small protein conjugation)|go:"GO:0033146"(regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050905"(neuromuscular process)|go:"GO:0061709"(reticulophagy)|go:"GO:0071566"(UFM1 activating enzyme activity)|go:"GO:0071569"(protein ufmylation)|go:"GO:1990592"(protein K69-linked ufmylation)|interpro:IPR000594(UBA/THIF-type NAD/FAD binding fold)|interpro:IPR029752|interpro:IPR035985|rcsb pdb:3GUC|rcsb pdb:3H8V|rcsb pdb:5HKH|rcsb pdb:5IA8|rcsb pdb:5IAA|rcsb pdb:5L95|rcsb pdb:6H77|rcsb pdb:6H78|rcsb pdb:6H8C|reactome:R-HSA-983168|entrezgene/locuslink:79876(identity)	-	crc64:881B91792AE91748	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:ujQYVD/yCqR8/T2eRPygiuTD7Jg559292	rogid:qEziScb8+GA1rGAqnWD5O1w7MIg9606	intact-crc:1CA6A451DB2E3407|rigid:1hPwqqR0NCPfLZp0/Inpe8QzEmk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P11972	uniprotkb:Q53EZ4	intact:EBI-18232|uniprotkb:Q06207|uniprotkb:D6VZ86|ensemblfungi:YLR452C	intact:EBI-747776|uniprotkb:Q32WF5|uniprotkb:Q3MV20|uniprotkb:Q5VY28|uniprotkb:Q6N034|ensembl:ENSP00000360540|uniprotkb:Q96H32|uniprotkb:Q9NVS7|uniprotkb:B2RDG8|intact:EBI-10173536|uniprotkb:D3DR37|intact:EBI-28973801	psi-mi:sst2_yeast(display_long)|uniprotkb:SST2(gene name)|psi-mi:SST2(display_short)|uniprotkb:L9324.9(orf name)|uniprotkb:YLR452C(locus name)	psi-mi:cep55_human(display_long)|uniprotkb:Up-regulated in colon cancer 6(gene name synonym)|uniprotkb:CEP55(gene name)|psi-mi:CEP55(display_short)|uniprotkb:URCC6(gene name synonym)|uniprotkb:C10orf3(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11523201|imex:IM-24995-96	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013557.1|sgd:S000004444|ensemblfungi:YLR452C(gene)|ensemblfungi:YLR452C_mRNA(transcript)|go:"GO:0000754"(adaptation of signaling pathway by response to pheromone involved in conjugation with cellular fusion)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0009968"(negative regulation of signal transduction)|go:"GO:0035556"(intracellular signal transduction)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR036305|interpro:IPR036388|interpro:IPR036390|interpro:IPR016137(Regulator of G protein signalling superfamily)|dip:DIP-2354N|mint:P11972|sgd:YLR452C(identity)	refseq:NP_001120654.1|refseq:NP_060601.3|ensembl:ENSG00000138180(gene)|ensembl:ENST00000371485(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0014066"(regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0030496"(midbody)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042802"(identical protein binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0061952"(midbody abscission)|go:"GO:0090543"(Flemming body)|go:"GO:1904888"(cranial skeletal system development)|interpro:IPR022008|interpro:IPR038926|mint:Q53EZ4|rcsb pdb:3E1R|rcsb pdb:3WUT|rcsb pdb:3WUU|rcsb pdb:3WUV|go:"GO:0005814"(centriole)|ensembl:ENSP00000360540|dip:DIP-44581N|entrezgene/locuslink:55165(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:a452jzptv3MtejNfc+LDrwSFSks559292	rogid:tuo36vVb8ZgPDR81YjZFNEg559w9606	intact-crc:B9DD4AA54A9EB3E2|rigid:2CY9YiVxtRxh2T3VgAvA03Km7O0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
intact:EBI-11523186	uniprotkb:P11747	-	intact:EBI-18897|uniprotkb:D6W0I7|ensemblfungi:YML098W	psi-mi:q5t063_human(display_short)|psi-mi:EBI-11523186(display_long)|uniprotkb:COQ3(gene name)|psi-mi:COQ3(display_short)	psi-mi:taf13_yeast(display_long)|uniprotkb:TAF13(gene name)|psi-mi:TAF13(display_short)|uniprotkb:FUN81(gene name synonym)|uniprotkb:TAF19(gene name synonym)|uniprotkb:YML098W(locus name)|uniprotkb:TBP-associated factor 13(gene name synonym)|uniprotkb:TBP-associated factor 19 kDa(gene name synonym)|uniprotkb:TAFII-19(gene name synonym)|uniprotkb:Function unknown 81 protein(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11523190|imex:IM-24995-95	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:Q5T063(uniprot-removed-ac)|entrezgene/locuslink:51805(identity)	refseq:NP_013611.1|sgd:S000004564|ensemblfungi:YML098W(gene)|ensemblfungi:YML098W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|interpro:IPR003195(Transcription initiation factor IID, 18 kDa subunit)|interpro:IPR009072(Histone-fold)|reactome:R-SCE-674695|reactome:R-SCE-6807505|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-76042|dip:DIP-2054N|mint:P11747|sgd:YML098W(identity)	-	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:A5Vp86bBACqUThgdTwfnKnqyE6c9606	rogid:N+MUCqLYlBQa1L2NcpyY5ImMIYM559292	intact-crc:F7229D13A7F7C351|rigid:8gx9Dw6LjBH5VRxbQobSaSpEuIc	false	sufficient binding region:61-310	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P11972	uniprotkb:Q8N6L0	intact:EBI-18232|uniprotkb:Q06207|uniprotkb:D6VZ86|ensemblfungi:YLR452C	intact:EBI-749265|uniprotkb:Q96MC3|ensembl:ENSP00000404220	psi-mi:sst2_yeast(display_long)|uniprotkb:SST2(gene name)|psi-mi:SST2(display_short)|uniprotkb:L9324.9(orf name)|uniprotkb:YLR452C(locus name)	psi-mi:kash5_human(display_long)|uniprotkb:KASH5(gene name)|psi-mi:KASH5(display_short)|uniprotkb:CCDC155(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 155(gene name synonym)|uniprotkb:KASH domain-containing protein 5(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11523210|imex:IM-24995-97	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013557.1|sgd:S000004444|ensemblfungi:YLR452C(gene)|ensemblfungi:YLR452C_mRNA(transcript)|go:"GO:0000754"(adaptation of signaling pathway by response to pheromone involved in conjugation with cellular fusion)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0009968"(negative regulation of signal transduction)|go:"GO:0035556"(intracellular signal transduction)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR036305|interpro:IPR036388|interpro:IPR036390|interpro:IPR016137(Regulator of G protein signalling superfamily)|dip:DIP-2354N|mint:P11972|sgd:YLR452C(identity)	refseq:NP_653289.3|ensembl:ENSG00000161609(gene)|ensembl:ENST00000447857(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034397"(telomere localization)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051225"(spindle assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0090172"(microtubule cytoskeleton organization involved in homologous chromosome segregation)|go:"GO:0090220"(chromosome localization to nuclear envelope involved in homologous chromosome segregation)|go:"GO:0090619"(meiotic spindle pole)|interpro:IPR011992(EF-Hand type)|interpro:IPR028168|interpro:IPR028170|interpro:IPR039508|mint:Q8N6L0|rcsb pdb:6R2I|rcsb pdb:6WMF|entrezgene/locuslink:147872(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:a452jzptv3MtejNfc+LDrwSFSks559292	rogid:Wl9L7AcvDHCZuKjYLn8QgGIbZTc9606	intact-crc:32E01E260CC5D4E4|rigid:rEa7jcAmNBUUvSpnXWFPLwT8+Fg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P13130	uniprotkb:Q9UMX0	intact:EBI-11523294|uniprotkb:D3DL88|ensemblfungi:YHR139C	intact:EBI-741480|uniprotkb:Q8IXS9|uniprotkb:Q8N2Q3|uniprotkb:Q9H0T8|uniprotkb:Q9H3R4|uniprotkb:Q9HAZ5|intact:EBI-28967608|ensembl:ENSP00000365576|uniprotkb:Q5T6J5|uniprotkb:Q5T6J9|uniprotkb:A0A024R284	psi-mi:ss100_yeast(display_long)|uniprotkb:SPS100(gene name)|psi-mi:SPS100(display_short)|uniprotkb:YHR139C(locus name)	psi-mi:ubql1_human(display_long)|uniprotkb:Protein linking IAP with cytoskeleton 1(gene name synonym)|uniprotkb:UBQLN1(gene name)|psi-mi:UBQLN1(display_short)|uniprotkb:DA41(gene name synonym)|uniprotkb:PLIC1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11523303|imex:IM-24995-107	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR006034(Asparaginase/glutaminase)|refseq:NP_012007.1|sgd:S000001181|ensemblfungi:YHR139C(gene)|ensemblfungi:YHR139C_mRNA(transcript)|go:"GO:0030476"(ascospore wall assembly)|interpro:IPR036152|sgd:YHR139C(identity)	ensembl:ENST00000257468|ensembl:ENSP00000257468|ensembl:ENSP00000365576|ensembl:ENSG00000135018(gene)|ensembl:ENST00000376395(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000502"(proteasome complex)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016235"(aggresome)|go:"GO:0016236"(macroautophagy)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0019900"(kinase binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035973"(aggrephagy)|go:"GO:0042802"(identical protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0097352"(autophagosome maturation)|go:"GO:1901340"(negative regulation of store-operated calcium channel activity)|go:"GO:1902175"(regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)|interpro:IPR000626(Ubiquitin)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR028430|interpro:IPR029071|mint:Q9UMX0|rcsb pdb:2JY5|rcsb pdb:2JY6|rcsb pdb:2KLC|reactome:R-HSA-8856825|refseq:NP_038466.2|refseq:NP_444295.1|dip:DIP-41629N|entrezgene/locuslink:29979(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/03/16	rogid:ThKMilyLHPEAiJu+3ty4DXcUEE4559292	rogid:nCFfZbGCTvRYaXhQ4R99XblslvM9606	intact-crc:C8E6CA8C9D2C723C|rigid:KGsi58uLomNB8/QsHP3n0SrQW/M	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P13130	uniprotkb:Q8TAP6	intact:EBI-11523294|uniprotkb:D3DL88|ensemblfungi:YHR139C	intact:EBI-742887|ensembl:ENSP00000262127|uniprotkb:Q658N5|uniprotkb:Q9H9U7|uniprotkb:B0YJB2|uniprotkb:B4DXG5|uniprotkb:B4DZW1	psi-mi:ss100_yeast(display_long)|uniprotkb:SPS100(gene name)|psi-mi:SPS100(display_short)|uniprotkb:YHR139C(locus name)	psi-mi:cep76_human(display_long)|uniprotkb:CEP76(gene name)|psi-mi:CEP76(display_short)|uniprotkb:C18orf9(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11523292|imex:IM-24995-106	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR006034(Asparaginase/glutaminase)|refseq:NP_012007.1|sgd:S000001181|ensemblfungi:YHR139C(gene)|ensemblfungi:YHR139C_mRNA(transcript)|go:"GO:0030476"(ascospore wall assembly)|interpro:IPR036152|sgd:YHR139C(identity)	refseq:NP_079175.2|ensembl:ENSG00000101624(gene)|ensembl:ENST00000262127(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0046599"(regulation of centriole replication)|interpro:IPR028926|interpro:IPR038765|mint:Q8TAP6|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_001258918.1|entrezgene/locuslink:79959(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/03/16	rogid:ThKMilyLHPEAiJu+3ty4DXcUEE4559292	rogid:fWzb8oIU35oVWomyDrf8u5sbxUk9606	intact-crc:AD21259234ADCDB4|rigid:YRjep4LcIYNbHrjtIgVJr+fIq6A	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8N6L0	uniprotkb:P12945	intact:EBI-749265|uniprotkb:Q96MC3|ensembl:ENSP00000404220	intact:EBI-11868|ensemblfungi:YDL040C|uniprotkb:D6VRV5	psi-mi:kash5_human(display_long)|uniprotkb:KASH5(gene name)|psi-mi:KASH5(display_short)|uniprotkb:CCDC155(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 155(gene name synonym)|uniprotkb:KASH domain-containing protein 5(gene name synonym)	psi-mi:nat1_yeast(display_long)|uniprotkb:NAT1(gene name)|psi-mi:NAT1(display_short)|uniprotkb:AAA1(gene name synonym)|uniprotkb:YDL040C(locus name)|uniprotkb:D2720(orf name)|uniprotkb:Amino-terminal, alpha-amino, acetyltransferase 1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11523283|imex:IM-24995-105	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_653289.3|ensembl:ENSG00000161609(gene)|ensembl:ENST00000447857(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034397"(telomere localization)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051225"(spindle assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0090172"(microtubule cytoskeleton organization involved in homologous chromosome segregation)|go:"GO:0090220"(chromosome localization to nuclear envelope involved in homologous chromosome segregation)|go:"GO:0090619"(meiotic spindle pole)|interpro:IPR011992(EF-Hand type)|interpro:IPR028168|interpro:IPR028170|interpro:IPR039508|mint:Q8N6L0|rcsb pdb:6R2I|rcsb pdb:6WMF|entrezgene/locuslink:147872(identity)	ensemblfungi:YDL040C(gene)|ensemblfungi:YDL040C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006474"(N-terminal protein amino acid acetylation)|go:"GO:0017196"(N-terminal peptidyl-methionine acetylation)|go:"GO:0031415"(NatA complex)|go:"GO:0043022"(ribosome binding)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR021183|rcsb pdb:4HNW|rcsb pdb:4HNY|rcsb pdb:4XNH|rcsb pdb:4XPD|rcsb pdb:4Y49|rcsb pdb:6HD5|rcsb pdb:6HD7|rcsb pdb:6O07|refseq:NP_010244.1|sgd:S000002198|dip:DIP-6329N|mint:P12945|sgd:YDL040C(identity)	-	-	crc64:DCFB870D049F91E6	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Wl9L7AcvDHCZuKjYLn8QgGIbZTc9606	rogid:uzbL/wNoQ9nAcZzglVrbI4GKzOg559292	intact-crc:F753272DBE3058B7|rigid:arqSMYQnLNdGXT0Ig8HGi8iPt2c	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q15041	uniprotkb:P12612	intact:EBI-714543|ensembl:ENSP00000306788|uniprotkb:B7Z6S5|uniprotkb:B7Z791|uniprotkb:F5GXP4	intact:EBI-19045|uniprotkb:D6VSJ6|ensemblfungi:YDR212W	psi-mi:ar6p1_human(display_long)|uniprotkb:ARL6IP(gene name synonym)|uniprotkb:ARL6IP1(gene name)|psi-mi:ARL6IP1(display_short)|uniprotkb:KIAA0069(gene name synonym)|uniprotkb:ARMER(gene name synonym)|uniprotkb:Apoptotic regulator in the membrane of the endoplasmic reticulum(gene name synonym)	psi-mi:tcpa_yeast(display_long)|uniprotkb:TCP1(gene name)|psi-mi:TCP1(display_short)|uniprotkb:CCT1(gene name synonym)|uniprotkb:YDR212W(locus name)|uniprotkb:YD8142.13(orf name)|uniprotkb:YD8142B.04(orf name)|uniprotkb:CCT-alpha(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11523237|imex:IM-24995-100	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055976.1|ensembl:ENSG00000170540(gene)|ensembl:ENST00000304414(transcript)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006613"(cotranslational protein targeting to membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0071787"(endoplasmic reticulum tubular network formation)|go:"GO:1903371"(regulation of endoplasmic reticulum tubular network organization)|go:"GO:1990809"(endoplasmic reticulum tubular network membrane organization)|interpro:IPR033301|mint:Q15041|go:"GO:0002038"(positive regulation of L-glutamate import across plasma membrane)|refseq:NP_001300787.1|entrezgene/locuslink:23204(identity)	refseq:NP_010498.1|sgd:S000002620|ensemblfungi:YDR212W(gene)|ensemblfungi:YDR212W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012715(T-complex protein 1, alpha subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|rcsb pdb:4V81|rcsb pdb:4V8R|rcsb pdb:4V94|rcsb pdb:5GW4|rcsb pdb:5GW5|rcsb pdb:6KRD|rcsb pdb:6KRE|rcsb pdb:6KS6|rcsb pdb:6KS7|rcsb pdb:6KS8|reactome:R-SCE-390471|reactome:R-SCE-6814122|dip:DIP-2965N|mint:P12612|sgd:YDR212W(identity)	-	-	crc64:02C625D329359E61	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:3fjkoyvUx25po7xsPcXgpjEeLJg9606	rogid:xWMsvY106Y6yQ54SOif2UlScafM559292	intact-crc:CB2D7E223877EF63|rigid:hg9kriFmHA5VRfK4C/zEWeN7Jeg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P12709	uniprotkb:Q13501	intact:EBI-7238|uniprotkb:D6VQJ0|ensemblfungi:YBR196C	intact:EBI-307104|uniprotkb:Q13446|uniprotkb:Q9BUV7|uniprotkb:Q9BVS6|uniprotkb:Q9UEU1|uniprotkb:A6NFN7|uniprotkb:B2R661|uniprotkb:B3KUW5|intact:EBI-28976133|ensembl:ENSP00000374455	psi-mi:g6pi_yeast(display_long)|uniprotkb:PGI1(gene name)|psi-mi:PGI1(display_short)|uniprotkb:YBR196C(locus name)|uniprotkb:YBR1406(orf name)|uniprotkb:Phosphoglucose isomerase(gene name synonym)|uniprotkb:Phosphohexose isomerase(gene name synonym)	psi-mi:sqstm_human(display_long)|uniprotkb:SQSTM1(gene name)|psi-mi:SQSTM1(display_short)|uniprotkb:ORCA(gene name synonym)|uniprotkb:OSIL(gene name synonym)|uniprotkb:Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa(gene name synonym)|uniprotkb:Ubiquitin-binding protein p62(gene name synonym)|uniprotkb:EBI3-associated protein of 60 kDa(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11523264|imex:IM-24995-103	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009755.1|sgd:S000000400|mint:P12709|dip:DIP-1605N|ensemblfungi:YBR196C(gene)|ensemblfungi:YBR196C_mRNA(transcript)|go:"GO:0004347"(glucose-6-phosphate isomerase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006096"(glycolytic process)|go:"GO:0048029"(monosaccharide binding)|go:"GO:0051156"(glucose 6-phosphate metabolic process)|interpro:IPR001672("Phosphoglucose isomerase (PGI)")|interpro:IPR018189|interpro:IPR023096|interpro:IPR035476|interpro:IPR035482|reactome:R-SCE-5628897|reactome:R-SCE-6798695|reactome:R-SCE-70171|reactome:R-SCE-70263|sgd:YBR196C(identity)	ensembl:ENST00000360718|ensembl:ENSP00000353944|ensembl:ENSP00000374455|ensembl:ENSG00000161011(gene)|ensembl:ENST00000389805(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0000423"(mitophagy)|go:"GO:0000932"(P-body)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002376"(immune system process)|go:"GO:0002931"(response to ischemia)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006914"(autophagy)|go:"GO:0006915"(apoptotic process)|go:"GO:0007032"(endosome organization)|go:"GO:0008104"(protein localization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016197"(endosomal transport)|go:"GO:0016234"(inclusion body)|go:"GO:0016235"(aggresome)|go:"GO:0016236"(macroautophagy)|go:"GO:0016605"(PML body)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030017"(sarcomere)|go:"GO:0030154"(cell differentiation)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035973"(aggrephagy)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046578"(regulation of Ras protein signal transduction)|go:"GO:0061635"(regulation of protein complex stability)|go:"GO:0061912"(selective autophagy)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:0097225"(sperm midpiece)|go:"GO:0097413"(Lewy body)|go:"GO:0098780"(response to mitochondrial depolarisation)|go:"GO:1900273"(positive regulation of long-term synaptic potentiation)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1905719"(protein localization to perinuclear region of cytoplasm)|interpro:IPR000270(Octicosapeptide/Phox/Bem1p)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR009060(UBA-like)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR033741|go:"GO:0044753"(amphisome)|interpro:IPR034866|interpro:IPR043145|mint:Q13501|rcsb pdb:1Q02|rcsb pdb:2JY7|rcsb pdb:2JY8|rcsb pdb:2K0B|rcsb pdb:2KNV|go:"GO:0044754"(autolysosome)|rcsb pdb:4MJS|rcsb pdb:4UF8|rcsb pdb:4UF9|go:"GO:0044877"(protein-containing complex binding)|rcsb pdb:5YP7|rcsb pdb:5YP8|rcsb pdb:5YPA|rcsb pdb:5YPB|rcsb pdb:5YPC|rcsb pdb:5YPE|rcsb pdb:5YPF|rcsb pdb:5YPG|rcsb pdb:5YPH|rcsb pdb:6JM4|rcsb pdb:6KHZ|rcsb pdb:6MJ7|rcsb pdb:6TGY|rcsb pdb:6TH3|reactome:R-HSA-205043|reactome:R-HSA-209543|reactome:R-HSA-209560|reactome:R-HSA-5205685|reactome:R-HSA-9020702|reactome:R-HSA-9664873|refseq:NP_001135770.1|refseq:NP_001135771.1|refseq:NP_003891.1|dip:DIP-34443N|refseq:XP_016865499.1|entrezgene/locuslink:8878(identity)	-	crc64:556D3D3B77EED052	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:hle82HMm3aAvYrUuuGoaxqyg/VA559292	rogid:paIcBLmyiv1+D9QMym5MY3yc8MI9606	intact-crc:6FF46A6BCE3DD6C6|rigid:qlvg6UNiNpdoIDTLjzlG09foy/w	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9C0F1	uniprotkb:P12612	intact:EBI-744115|uniprotkb:A8K8W9|uniprotkb:B3KT53|uniprotkb:Q8IXZ4|uniprotkb:A8MW11|uniprotkb:D3DP42|ensembl:ENSP00000296519|ensembl:ENSP00000380009|ensembl:ENSP00000423153	intact:EBI-19045|uniprotkb:D6VSJ6|ensemblfungi:YDR212W	psi-mi:cep44_human(display_long)|uniprotkb:HBV PreS1-transactivated protein 3(gene name synonym)|uniprotkb:CEP44(gene name)|psi-mi:CEP44(display_short)|uniprotkb:KIAA1712(gene name synonym)	psi-mi:tcpa_yeast(display_long)|uniprotkb:TCP1(gene name)|psi-mi:TCP1(display_short)|uniprotkb:CCT1(gene name synonym)|uniprotkb:YDR212W(locus name)|uniprotkb:YD8142.13(orf name)|uniprotkb:YD8142B.04(orf name)|uniprotkb:CCT-alpha(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11523255|imex:IM-24995-102	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001035247.1|refseq:NP_001138786.1|refseq:XP_011530587.1|refseq:XP_011530588.1|refseq:XP_011530589.1|refseq:XP_016864143.1|refseq:XP_016864144.1|ensembl:ENSG00000164118(gene)|ensembl:ENST00000296519(transcript)|ensembl:ENST00000396791(transcript)|ensembl:ENST00000503780(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007099"(centriole replication)|go:"GO:0008017"(microtubule binding)|go:"GO:0010457"(centriole-centriole cohesion)|go:"GO:0030496"(midbody)|interpro:IPR029157|interpro:IPR033603|mint:Q9C0F1|entrezgene/locuslink:80817(identity)	refseq:NP_010498.1|sgd:S000002620|ensemblfungi:YDR212W(gene)|ensemblfungi:YDR212W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012715(T-complex protein 1, alpha subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|rcsb pdb:4V81|rcsb pdb:4V8R|rcsb pdb:4V94|rcsb pdb:5GW4|rcsb pdb:5GW5|rcsb pdb:6KRD|rcsb pdb:6KRE|rcsb pdb:6KS6|rcsb pdb:6KS7|rcsb pdb:6KS8|reactome:R-SCE-390471|reactome:R-SCE-6814122|dip:DIP-2965N|mint:P12612|sgd:YDR212W(identity)	-	-	crc64:02C625D329359E61	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:gDTC64oDhudGdsssC7v+suIHZkA9606	rogid:xWMsvY106Y6yQ54SOif2UlScafM559292	intact-crc:BD2CC77017AC948B|rigid:/6ENGopr6rtDq1OlgLpBBq/+eik	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P12612	uniprotkb:Q96BR9	intact:EBI-19045|uniprotkb:D6VSJ6|ensemblfungi:YDR212W	intact:EBI-742740|uniprotkb:Q8IUL5|uniprotkb:Q8IWR9|uniprotkb:Q8N2Y5|uniprotkb:Q96BX0|ensembl:ENSP00000362609	psi-mi:tcpa_yeast(display_long)|uniprotkb:TCP1(gene name)|psi-mi:TCP1(display_short)|uniprotkb:CCT1(gene name synonym)|uniprotkb:YDR212W(locus name)|uniprotkb:YD8142.13(orf name)|uniprotkb:YD8142B.04(orf name)|uniprotkb:CCT-alpha(gene name synonym)	psi-mi:zbt8a_human(display_long)|uniprotkb:ZBTB8A(gene name)|psi-mi:ZBTB8A(display_short)|uniprotkb:BOZF1(gene name synonym)|uniprotkb:BTB/POZ and zinc-finger domain-containing factor(gene name synonym)|uniprotkb:BTB/POZ and zinc-finger domains factor on chromosome 1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11523246|imex:IM-24995-101	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010498.1|sgd:S000002620|ensemblfungi:YDR212W(gene)|ensemblfungi:YDR212W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012715(T-complex protein 1, alpha subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|rcsb pdb:4V81|rcsb pdb:4V8R|rcsb pdb:4V94|rcsb pdb:5GW4|rcsb pdb:5GW5|rcsb pdb:6KRD|rcsb pdb:6KRE|rcsb pdb:6KS6|rcsb pdb:6KS7|rcsb pdb:6KS8|reactome:R-SCE-390471|reactome:R-SCE-6814122|dip:DIP-2965N|mint:P12612|sgd:YDR212W(identity)	ensembl:ENSG00000160062(gene)|ensembl:ENST00000373510(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|refseq:NP_001035531.2|refseq:NP_001278425.1|entrezgene/locuslink:653121(identity)	-	crc64:02C625D329359E61	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:xWMsvY106Y6yQ54SOif2UlScafM559292	rogid:tsrPT2tHvuBryODKgRXnceXz9s09606	intact-crc:B218BF16416FE555|rigid:eOKcrORbn1aYRa7IKh+kR33ysqI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q15025	uniprotkb:P12945	intact:EBI-357849|uniprotkb:A4F1W8|uniprotkb:O76008|uniprotkb:Q96EL9|uniprotkb:Q99833|uniprotkb:Q9H1J3|uniprotkb:B7Z699|uniprotkb:Q6N077|ensembl:ENSP00000317891|ensembl:ENSP00000428187|ensembl:ENSP00000430760|uniprotkb:A4F1W9|uniprotkb:A4F1X2|uniprotkb:A4F1X4|uniprotkb:A4F1X5|uniprotkb:A4F1X6|uniprotkb:A4F1X7|uniprotkb:A4F1X9|uniprotkb:E7EPY1|uniprotkb:E7ET96|uniprotkb:Q05KP3|uniprotkb:Q05KP4	intact:EBI-11868|ensemblfungi:YDL040C|uniprotkb:D6VRV5	psi-mi:tnip1_human(display_long)|uniprotkb:TNIP1(gene name)|psi-mi:TNIP1(display_short)|uniprotkb:KIAA0113(gene name synonym)|uniprotkb:NAF1(gene name synonym)|uniprotkb:Nef-associated factor 1(gene name synonym)|uniprotkb:HIV-1 Nef-interacting protein(gene name synonym)|uniprotkb:Virion-associated nuclear shuttling protein(gene name synonym)|uniprotkb:Nip40-1(gene name synonym)|uniprotkb:A20-binding inhibitor of NF-kappa-B activation 1(gene name synonym)	psi-mi:nat1_yeast(display_long)|uniprotkb:NAT1(gene name)|psi-mi:NAT1(display_short)|uniprotkb:AAA1(gene name synonym)|uniprotkb:YDL040C(locus name)|uniprotkb:D2720(orf name)|uniprotkb:Amino-terminal, alpha-amino, acetyltransferase 1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11523273|imex:IM-24995-104	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006049.3|refseq:NP_001239319.1|refseq:NP_001239320.1|refseq:NP_001239321.1|refseq:NP_001239322.1|refseq:NP_001245383.1|dip:DIP-27577N|refseq:NP_001239315.1|ensembl:ENSG00000145901(gene)|ensembl:ENST00000315050(transcript)|ensembl:ENST00000521591(transcript)|ensembl:ENST00000522226(transcript)|go:"GO:0002755"(MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0006952"(defense response)|go:"GO:0006954"(inflammatory response)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0009101"(glycoprotein biosynthetic process)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0085032"(modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade)|go:"GO:1903003"(positive regulation of protein deubiquitination)|interpro:IPR033372|mint:Q15025|reactome:R-HSA-5689896|go:"GO:0051019"(mitogen-activated protein kinase binding)|refseq:NP_001239314.1|refseq:NP_001245384.1|refseq:NP_001245385.1|refseq:XP_006714814.1|refseq:XP_006714815.1|entrezgene/locuslink:10318(identity)	ensemblfungi:YDL040C(gene)|ensemblfungi:YDL040C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006474"(N-terminal protein amino acid acetylation)|go:"GO:0017196"(N-terminal peptidyl-methionine acetylation)|go:"GO:0031415"(NatA complex)|go:"GO:0043022"(ribosome binding)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR021183|rcsb pdb:4HNW|rcsb pdb:4HNY|rcsb pdb:4XNH|rcsb pdb:4XPD|rcsb pdb:4Y49|rcsb pdb:6HD5|rcsb pdb:6HD7|rcsb pdb:6O07|refseq:NP_010244.1|sgd:S000002198|dip:DIP-6329N|mint:P12945|sgd:YDL040C(identity)	-	-	crc64:DCFB870D049F91E6	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:16Vjb5CuGTAbW2M22qbCxgXtV1o9606	rogid:uzbL/wNoQ9nAcZzglVrbI4GKzOg559292	intact-crc:835CCE5C39BEBAAC|rigid:nJkoXSkwLxk4qiNvOrjpzpV7Uos	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P15202	uniprotkb:Q9ULX6	intact:EBI-4061|uniprotkb:E9P947|uniprotkb:D6VSN6|ensemblfungi:YDR256C	intact:EBI-357530|uniprotkb:O94792|uniprotkb:Q96J58|uniprotkb:Q9NRQ0|uniprotkb:Q9UGM0|uniprotkb:B5BU90|uniprotkb:B4DJ74|ensembl:ENSP00000380557	psi-mi:cata_yeast(display_long)|uniprotkb:YD9320A.06C(orf name)|uniprotkb:YDR256C(locus name)|uniprotkb:CTA1(gene name)|psi-mi:CTA1(display_short)	psi-mi:akp8l_human(display_long)|uniprotkb:AKAP8L(gene name)|psi-mi:AKAP8L(display_short)|uniprotkb:HRIHFB2018(orf name)|uniprotkb:NAKAP95(gene name synonym)|uniprotkb:Neighbor of A-kinase-anchoring protein 95(gene name synonym)|uniprotkb:Homologous to AKAP95 protein(gene name synonym)|uniprotkb:Helicase A-binding protein 95(gene name synonym)|uniprotkb:NAKAP(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11523369|imex:IM-24995-113	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002664|refseq:NP_010542.1|dip:DIP-4320N|mint:P15202|ensemblfungi:YDR256C(gene)|ensemblfungi:YDR256C_mRNA(transcript)|go:"GO:0000302"(response to reactive oxygen species)|go:"GO:0001315"(age-dependent response to reactive oxygen species)|go:"GO:0004096"(catalase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005777"(peroxisome)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0020037"(heme binding)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0046872"(metal ion binding)|interpro:IPR002226(Catalase)|interpro:IPR010582(Catalase-related)|interpro:IPR011614(Catalase, N-terminal)|interpro:IPR018028|interpro:IPR020835|interpro:IPR024708|interpro:IPR024711|rcsb pdb:1A4E|sgd:YDR256C(identity)	refseq:NP_001278407.1|refseq:NP_055186.3|dip:DIP-27541N|ensembl:ENSG00000011243(gene)|ensembl:ENST00000397410(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010793"(regulation of mRNA export from nucleus)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016605"(PML body)|go:"GO:0016607"(nuclear speck)|go:"GO:0017151"(DEAD/H-box RNA helicase binding)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0033127"(regulation of histone phosphorylation)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0044839"(cell cycle G2/M phase transition)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0051081"(nuclear membrane disassembly)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR007071("A-kinase anchoring protein 95 (AKAP95)")|interpro:IPR034736|mint:Q9ULX6|entrezgene/locuslink:26993(identity)	-	crc64:22DFCC599D79801F	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2018/09/18	rogid:+NMosmB3jzYGleF7X88sJ2qLm/Y559292	rogid:SAs8jxuWxLOiWN/TRyjVvr5m/5Y9606	intact-crc:0B10A6009995984A|rigid:MQs7mJ+EXKvoppESJeluyw51LxA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P15202	uniprotkb:Q9NRG1	intact:EBI-4061|uniprotkb:E9P947|uniprotkb:D6VSN6|ensemblfungi:YDR256C	intact:EBI-739759|uniprotkb:Q53HA7|uniprotkb:Q59EL9|uniprotkb:Q5VV18|uniprotkb:Q5VV20|uniprotkb:B7Z1Z3|ensembl:ENSP00000318602	psi-mi:cata_yeast(display_long)|uniprotkb:YD9320A.06C(orf name)|uniprotkb:YDR256C(locus name)|uniprotkb:CTA1(gene name)|psi-mi:CTA1(display_short)	psi-mi:prdc1_human(display_long)|uniprotkb:PRTFDC1(gene name)|psi-mi:PRTFDC1(display_short)|uniprotkb:HHGP(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11523360|imex:IM-24995-112	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002664|refseq:NP_010542.1|dip:DIP-4320N|mint:P15202|ensemblfungi:YDR256C(gene)|ensemblfungi:YDR256C_mRNA(transcript)|go:"GO:0000302"(response to reactive oxygen species)|go:"GO:0001315"(age-dependent response to reactive oxygen species)|go:"GO:0004096"(catalase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005777"(peroxisome)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0020037"(heme binding)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0046872"(metal ion binding)|interpro:IPR002226(Catalase)|interpro:IPR010582(Catalase-related)|interpro:IPR011614(Catalase, N-terminal)|interpro:IPR018028|interpro:IPR020835|interpro:IPR024708|interpro:IPR024711|rcsb pdb:1A4E|sgd:YDR256C(identity)	refseq:NP_001269715.1|refseq:NP_064585.1|ensembl:ENSG00000099256(gene)|ensembl:ENST00000320152(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0006166"(purine ribonucleoside salvage)|go:"GO:0042803"(protein homodimerization activity)|interpro:IPR000836(Phosphoribosyltransferase)|interpro:IPR005904(Hypoxanthine phosphoribosyl transferase)|interpro:IPR029057|rcsb pdb:2JBH|entrezgene/locuslink:56952(identity)	-	crc64:22DFCC599D79801F	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:+NMosmB3jzYGleF7X88sJ2qLm/Y559292	rogid:grTZnSalFILRSeeZBjM1mTtF0xo9606	intact-crc:0234D15BED0619DF|rigid:9q7gYQNJc5B+h4/yED4XUFOSjUs	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P13130	uniprotkb:Q9Y5P4-2	intact:EBI-11523294|uniprotkb:D3DL88|ensemblfungi:YHR139C	intact:EBI-11156432|ensembl:ENSP00000493563|ensembl:ENSP00000495446|ensembl:ENSP00000496243	psi-mi:ss100_yeast(display_long)|uniprotkb:SPS100(gene name)|psi-mi:SPS100(display_short)|uniprotkb:YHR139C(locus name)	psi-mi:q9y5p4-2(display_long)|uniprotkb:Goodpasture antigen-binding protein(gene name synonym)|uniprotkb:STARD11(gene name synonym)|uniprotkb:START domain-containing protein 11(gene name synonym)|uniprotkb:StAR-related lipid transfer protein 11(gene name synonym)|uniprotkb:CERT(isoform synonym)|uniprotkb:Delta26(isoform synonym)|uniprotkb:GPBPD26(isoform synonym)|uniprotkb:CERT(gene name synonym)|uniprotkb:COL4A3BP(gene name synonym)|uniprotkb:CERT1(gene name)|psi-mi:CERT1(display_short)|uniprotkb:Collagen type IV alpha-3-binding protein(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11523312|imex:IM-24995-108	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR006034(Asparaginase/glutaminase)|refseq:NP_012007.1|sgd:S000001181|ensemblfungi:YHR139C(gene)|ensemblfungi:YHR139C_mRNA(transcript)|go:"GO:0030476"(ascospore wall assembly)|interpro:IPR036152|sgd:YHR139C(identity)	ensembl:ENSG00000113163(gene)|ensembl:ENST00000644445(transcript)|ensembl:ENST00000645483(transcript)|ensembl:ENST00000646511(transcript)|intact:EBI-739994(isoform-parent)|uniprotkb:Q9Y5P4-2(isoform-parent)|entrezgene/locuslink:10087(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/03/16	rogid:ThKMilyLHPEAiJu+3ty4DXcUEE4559292	rogid:UXQeqtW4rknHeYKQlqBZ9HMX8Qs9606	intact-crc:324B2145436A1CA5|rigid:VsTEV5Bu7ezKNSFK0ZMGd3Tp0yo	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P14905	uniprotkb:O95273	intact:EBI-4163|uniprotkb:D6VSI0|ensemblfungi:YDR197W	intact:EBI-748961|uniprotkb:A8K3Q0|uniprotkb:A8K3U2|uniprotkb:Q6ZQN9|uniprotkb:Q7Z519|uniprotkb:Q8NBS7|uniprotkb:Q8NBY2|uniprotkb:Q9NS19|uniprotkb:Q9NYH3|uniprotkb:Q9UHX9|ensembl:ENSP00000300213	psi-mi:cbs2_yeast(display_long)|uniprotkb:CBS2(gene name)|psi-mi:CBS2(display_short)|uniprotkb:CBP7(gene name synonym)|uniprotkb:YDR197W(locus name)|uniprotkb:YD9346.08(orf name)	psi-mi:ccdb1_human(display_long)|uniprotkb:Grap2 and cyclin-D-interacting protein(gene name synonym)|uniprotkb:Human homolog of Maid(gene name synonym)|uniprotkb:CCNDBP1(gene name)|psi-mi:CCNDBP1(display_short)|uniprotkb:DIP1(gene name synonym)|uniprotkb:GCIP(gene name synonym)|uniprotkb:HHM(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11523336|imex:IM-24995-110	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010483.1|sgd:S000002605|interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|interpro:IPR013752(Ketopantoate reductase ApbA/PanE, C-terminal)|interpro:IPR013328(Dehydrogenase, multihelical)|ensemblfungi:YDR197W(gene)|ensemblfungi:YDR197W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005761"(mitochondrial ribosome)|go:"GO:0008677"(2-dehydropantoate 2-reductase activity)|go:"GO:0031314"(extrinsic component of mitochondrial inner membrane)|go:"GO:0045182"(translation regulator activity)|go:"GO:0050661"(NADP binding)|go:"GO:0070131"(positive regulation of mitochondrial translation)|sgd:YDR197W(identity)	refseq:NP_036274.3|ensembl:ENSG00000166946(gene)|ensembl:ENST00000300213(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0016604"(nuclear body)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR026907|mint:O95273|rcsb pdb:3AY5|entrezgene/locuslink:23582(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:KEEVJQEjHPVx7AU4JFmwGnoEptU559292	rogid:Vi9aoFc+Mov6P3X6KGmsTxXqxvM9606	intact-crc:89D2811610D8721A|rigid:q/3T4XXuCPOQCtjMxHiqDceUpZU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q86V42-3	uniprotkb:P13186	intact:EBI-11523323|ensembl:ENSP00000481212	intact:EBI-9723|uniprotkb:Q12384|ensemblfungi:YLR096W|uniprotkb:D6VY96	psi-mi:q86v42-3(display_long)|uniprotkb:FAM124A(gene name)|psi-mi:FAM124A(display_short)	psi-mi:kin2_yeast(display_long)|uniprotkb:L8004.3(orf name)|uniprotkb:YLR096W(locus name)|uniprotkb:KIN2(gene name)|psi-mi:KIN2(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11523321|imex:IM-24995-109	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000150510(gene)|ensembl:ENST00000615498(transcript)|intact:EBI-744506(isoform-parent)|entrezgene/locuslink:220108(identity)	go:"GO:0005935"(cellular bud neck)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006887"(exocytosis)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0045921"(positive regulation of exocytosis)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903896"(positive regulation of IRE1-mediated unfolded protein response)|interpro:IPR000719(Protein kinase, core)|ensemblfungi:YLR096W(gene)|ensemblfungi:YLR096W_mRNA(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005934"(cellular bud tip)|interpro:IPR001772(Kinase-associated KA1)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR028375|reactome:R-SCE-1632852|reactome:R-SCE-380972|refseq:NP_013197.1|sgd:S000004086|dip:DIP-6276N|mint:P13186|sgd:YLR096W(identity)	-	-	crc64:AC2660BF3CA69600	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:tWx14HsCfMtI8yIrYJCt8V4lr+c9606	rogid:OkRLTXiGL1oYkrvvB/KznlaEvrE559292	intact-crc:E7539545873B10F1|rigid:col8/KUv7mr3nLS9KHMq/YIXCnM	false	sufficient binding region:1-288	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P14907	uniprotkb:Q8IYF3-3	intact:EBI-12265|uniprotkb:D6VWE3	intact:EBI-11523345|ensembl:ENSP00000363453	psi-mi:nsp1_yeast(display_long)|uniprotkb:NSP1(gene name)|psi-mi:NSP1(display_short)|uniprotkb:YJL041W(locus name)|uniprotkb:J1207(orf name)|uniprotkb:Nuclear pore protein NSP1(gene name synonym)|uniprotkb:Nucleoskeletal-like protein(gene name synonym)|uniprotkb:p110(gene name synonym)	psi-mi:q8iyf3-3(display_long)|uniprotkb:TEX11(gene name)|psi-mi:TEX11(display_short)|uniprotkb:Protein ZIP4 homolog(gene name synonym)|uniprotkb:ZIP4(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11523349|imex:IM-24995-111	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005643"(nuclear pore)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006409"(tRNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034399"(nuclear periphery)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0044615"(nuclear pore nuclear basket)|go:"GO:0097064"(ncRNA export from nucleus)|interpro:IPR007758(Nucleoporin, Nsp1-like, C-terminal)|interpro:IPR026010|rcsb pdb:1O6O|refseq:NP_012494.3|sgd:S000003577|mint:P14907|dip:DIP-1484N|sgd:YJL041W(identity)	ensembl:ENSG00000120498(gene)|ensembl:ENST00000374333(transcript)|intact:EBI-742397(isoform-parent)|uniprotkb:Q8IYF3-3(isoform-parent)|entrezgene/locuslink:56159(identity)	-	crc64:A258003CB1917810	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:wFdC6D8JzkhJpF+k3qtnFj9+4pA559292	rogid:PUAMFmnm5ZV2rnJ1rhm9ZeRCixg9606	intact-crc:8D102891DC219765|rigid:Vos9JzohYWyh3B2VJRQIX3CQZAE	false	-	sufficient binding region:9-925	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P15625	uniprotkb:O15162	intact:EBI-18678|uniprotkb:D6VTK8|ensemblfungi:YFL022C	intact:EBI-740019|ensembl:ENSP00000345494|uniprotkb:B2R8H8|uniprotkb:B4DTE8	psi-mi:syfa_yeast(display_long)|uniprotkb:FRS2(gene name)|psi-mi:FRS2(display_short)|uniprotkb:Phenylalanyl-tRNA synthetase alpha subunit(gene name synonym)|uniprotkb:YFL022C(locus name)	psi-mi:pls1_human(display_long)|uniprotkb:PLSCR1(gene name)|psi-mi:PLSCR1(display_short)|uniprotkb:"Ca(2+)-dependent phospholipid scramblase 1"(gene name synonym)|uniprotkb:Erythrocyte phospholipid scramblase(gene name synonym)|uniprotkb:MmTRA1b(gene name synonym)|uniprotkb:"Mg(2+)-dependent nuclease"(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11523414|imex:IM-24995-118	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_116631.1|sgd:S000001872|ensemblfungi:YFL022C(gene)|ensemblfungi:YFL022C_mRNA(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0002161"(aminoacyl-tRNA editing activity)|go:"GO:0004826"(phenylalanine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006432"(phenylalanyl-tRNA aminoacylation)|go:"GO:0009328"(phenylalanine-tRNA ligase complex)|interpro:IPR002319(Phenylalanyl-tRNA synthetase, class IIc)|interpro:IPR004529(Phenylalanyl-tRNA synthetase, class IIc, alpha subunit)|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR040586|interpro:IPR040725|dip:DIP-5428N|mint:P15625|sgd:YFL022C(identity)	ensembl:ENSG00000188313(gene)|ensembl:ENST00000342435(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001618"(virus receptor activity)|go:"GO:0003677"(DNA binding)|go:"GO:0004518"(nuclease activity)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006659"(phosphatidylserine biosynthetic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0006953"(acute-phase response)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010288"(response to lead ion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0017121"(plasma membrane phospholipid scrambling)|go:"GO:0017124"(SH3 domain binding)|ensembl:ENSP00000345494|ensembl:ENST00000448787|ensembl:ENSP00000411675|refseq:NP_066928.1|go:"GO:0017128"(phospholipid scramblase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030168"(platelet activation)|go:"GO:0032791"(lead ion binding)|go:"GO:0033003"(regulation of mast cell activation)|go:"GO:0035456"(response to interferon-beta)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0045340"(mercury ion binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0051607"(defense response to virus)|go:"GO:0060368"(regulation of Fc receptor mediated stimulatory signaling pathway)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070782"(phosphatidylserine exposure on apoptotic cell surface)|go:"GO:1905820"(positive regulation of chromosome separation)|go:"GO:2000373"("positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity")|interpro:IPR005552(Scramblase)|mint:O15162|rcsb pdb:1Y2A|refseq:XP_011511209.1|refseq:XP_011511206.1|refseq:XP_005247595.1|refseq:XP_011511208.1|refseq:XP_016862118.1|entrezgene/locuslink:5359(identity)	-	crc64:50B7EAC675AB559B	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:hOEtrjcfIHQLY9FwCDb3XI593A4559292	rogid:XudfvUkrZbB28t9tpFkokgnDFGc9606	intact-crc:EA5E35F8D1EFFB33|rigid:7WyGodAFnXD8EApEF8VHsdlfy+A	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P15365	uniprotkb:Q969F0	intact:EBI-5527|uniprotkb:D6VWX1|ensemblfungi:YJR152W	intact:EBI-743099|ensembl:ENSP00000359375	psi-mi:dal5_yeast(display_long)|uniprotkb:DAL5(gene name)|psi-mi:DAL5(display_short)|uniprotkb:UREP1(gene name synonym)|uniprotkb:YJR152W(locus name)|uniprotkb:J2230(orf name)	psi-mi:fate1_human(display_long)|uniprotkb:Tumor antigen BJ-HCC-2(gene name synonym)|uniprotkb:Cancer/testis antigen 43(gene name synonym)|uniprotkb:FATE1(gene name)|psi-mi:FATE1(display_short)|uniprotkb:FATE(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11523405|imex:IM-24995-117	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003913|refseq:NP_012686.3|dip:DIP-7873N|mint:P15365|ensemblfungi:YJR152W(gene)|ensemblfungi:YJR152W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0015124"(allantoate transmembrane transporter activity)|go:"GO:0015719"(allantoate transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0031224"(intrinsic component of membrane)|go:"GO:0042938"(dipeptide transport)|go:"GO:0042939"(tripeptide transport)|go:"GO:0071916"(dipeptide transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR036259|sgd:YJR152W(identity)	refseq:NP_149076.1|ensembl:ENSG00000147378(gene)|ensembl:ENST00000370350(transcript)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|go:"GO:0051562"(negative regulation of mitochondrial calcium ion concentration)|interpro:IPR039153|interpro:IPR039433|mint:Q969F0|entrezgene/locuslink:89885(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Y2kCv3dK4Hjn9hJpK+WK5rp6VKU559292	rogid:Nm1N6lO92MHr5rIKC007oouF5RE9606	intact-crc:E22089125A9838E5|rigid:RD0RDUauwGS/643juHawjhQo/4A	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O75477	uniprotkb:P15303	intact:EBI-359299|uniprotkb:B0QZ42|uniprotkb:Q53HV0|ensembl:ENSP00000384900|ensembl:ENSP00000410964|intact:EBI-21351077|uniprotkb:D3DR65	intact:EBI-16584|ensemblfungi:YPR181C|uniprotkb:D6W4I1	psi-mi:erln1_human(display_long)|uniprotkb:KEO4(gene name synonym)|uniprotkb:ERLIN1(gene name)|psi-mi:ERLIN1(display_short)|uniprotkb:C10orf69(gene name synonym)|uniprotkb:KE04(gene name synonym)|uniprotkb:SPFH1(gene name synonym)|uniprotkb:Endoplasmic reticulum lipid raft-associated protein 1(gene name synonym)|uniprotkb:Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 1(gene name synonym)|uniprotkb:Protein KE04(gene name synonym)	psi-mi:sec23_yeast(display_long)|uniprotkb:SEC23(gene name)|psi-mi:SEC23(display_short)|uniprotkb:P9705.14(orf name)|uniprotkb:YPR181C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11523378|imex:IM-24995-114	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001094096.1|refseq:NP_006450.2|ensembl:ENSG00000107566(gene)|ensembl:ENST00000407654(transcript)|ensembl:ENST00000421367(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032933"(SREBP signaling pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045541"(negative regulation of cholesterol biosynthetic process)|go:"GO:0045717"(negative regulation of fatty acid biosynthetic process)|interpro:IPR001107(Band 7 protein)|interpro:IPR033294|interpro:IPR036013|mint:O75477|reactome:R-HSA-382556|reactome:R-HSA-5678895|refseq:NP_001334786.1|refseq:NP_001334788.1|refseq:NP_001334789.1|refseq:NP_001334790.1|entrezgene/locuslink:10613(identity)	refseq:NP_015507.1|sgd:S000006385|ensemblfungi:YPR181C(gene)|ensemblfungi:YPR181C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003400"(regulation of COPII vesicle coating)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016236"(macroautophagy)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0061709"(reticulophagy)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:0090110"(COPII-coated vesicle cargo loading)|interpro:IPR006895(Zinc finger, Sec23/Sec24-type)|interpro:IPR006896(Sec23/Sec24 trunk region)|interpro:IPR006900(Sec23/Sec24 helical region)|interpro:IPR007123(Gelsolin region)|interpro:IPR012990(Sec23/Sec24 beta-sandwich)|interpro:IPR029006|interpro:IPR036174|interpro:IPR036175|interpro:IPR036180|interpro:IPR036465|interpro:IPR037364|interpro:IPR037550|rcsb pdb:1M2O|rcsb pdb:2QTV|rcsb pdb:4BZI|rcsb pdb:6GNI|rcsb pdb:6ZGA|reactome:R-SCE-204005|reactome:R-SCE-5694530|reactome:R-SCE-983170|rcsb pdb:1M2V|dip:DIP-2232N|mint:P15303|sgd:YPR181C(identity)	-	-	crc64:69811913848265FB	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2019/05/28	rogid:HycFhL5qL5GLmaIIc9NtTcBbu1M9606	rogid:IqC3qOrbef6aMHBztUW5+7DZ4IQ559292	intact-crc:8FED6439D09A5AC4|rigid:uipxd6WuchHbeGrUAlWl4Mm1AYo	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8IYX7	uniprotkb:P15303	intact:EBI-3957636|ensembl:ENSP00000369907|intact:EBI-10174528|uniprotkb:A8K880|uniprotkb:Q5VY58	intact:EBI-16584|ensemblfungi:YPR181C|uniprotkb:D6W4I1	psi-mi:saxo1_human(display_long)|uniprotkb:SAXO1(gene name)|psi-mi:SAXO1(display_short)|uniprotkb:C9orf138(gene name synonym)|uniprotkb:FAM154A(gene name synonym)	psi-mi:sec23_yeast(display_long)|uniprotkb:SEC23(gene name)|psi-mi:SEC23(display_short)|uniprotkb:P9705.14(orf name)|uniprotkb:YPR181C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11523387|imex:IM-24995-115	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000155875(gene)|ensembl:ENST00000380534(transcript)|go:"GO:0005814"(centriole)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0008017"(microtubule binding)|go:"GO:0009631"(cold acclimation)|go:"GO:0030030"(cell projection organization)|go:"GO:0031514"(motile cilium)|go:"GO:0034453"(microtubule anchoring)|go:"GO:0036064"(ciliary basal body)|go:"GO:0036126"(sperm flagellum)|go:"GO:0045724"(positive regulation of cilium assembly)|go:"GO:0050821"(protein stabilization)|go:"GO:0070417"(cellular response to cold)|interpro:IPR033336|refseq:NP_714918.2|refseq:NP_001273978.1|refseq:NP_001273979.1|entrezgene/locuslink:158297(identity)	refseq:NP_015507.1|sgd:S000006385|ensemblfungi:YPR181C(gene)|ensemblfungi:YPR181C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003400"(regulation of COPII vesicle coating)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016236"(macroautophagy)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0061709"(reticulophagy)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:0090110"(COPII-coated vesicle cargo loading)|interpro:IPR006895(Zinc finger, Sec23/Sec24-type)|interpro:IPR006896(Sec23/Sec24 trunk region)|interpro:IPR006900(Sec23/Sec24 helical region)|interpro:IPR007123(Gelsolin region)|interpro:IPR012990(Sec23/Sec24 beta-sandwich)|interpro:IPR029006|interpro:IPR036174|interpro:IPR036175|interpro:IPR036180|interpro:IPR036465|interpro:IPR037364|interpro:IPR037550|rcsb pdb:1M2O|rcsb pdb:2QTV|rcsb pdb:4BZI|rcsb pdb:6GNI|rcsb pdb:6ZGA|reactome:R-SCE-204005|reactome:R-SCE-5694530|reactome:R-SCE-983170|rcsb pdb:1M2V|dip:DIP-2232N|mint:P15303|sgd:YPR181C(identity)	-	-	crc64:69811913848265FB	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:34It0miSDTtv5wwJ+ERHXJzWRiQ9606	rogid:IqC3qOrbef6aMHBztUW5+7DZ4IQ559292	intact-crc:F6077808C471B67C|rigid:CcnZTitK+IXIqlud5ojOCUOJdcs	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9BSE2	uniprotkb:P15303	intact:EBI-8649725|ensembl:ENSP00000295694|ensembl:ENSP00000384748|intact:MINT-8163648|uniprotkb:D3DVB8|uniprotkb:B2RE22	intact:EBI-16584|ensemblfungi:YPR181C|uniprotkb:D6W4I1	psi-mi:tmm79_human(display_long)|uniprotkb:MATT(gene name synonym)|uniprotkb:TMEM79(gene name)|psi-mi:TMEM79(display_short)|uniprotkb:Mattrin(gene name synonym)	psi-mi:sec23_yeast(display_long)|uniprotkb:SEC23(gene name)|psi-mi:SEC23(display_short)|uniprotkb:P9705.14(orf name)|uniprotkb:YPR181C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11523396|imex:IM-24995-116	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000163472(gene)|ensembl:ENST00000295694(transcript)|ensembl:ENST00000405535(transcript)|go:"GO:0002070"(epithelial cell maturation)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031069"(hair follicle morphogenesis)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0042335"(cuticle development)|go:"GO:0042802"(identical protein binding)|go:"GO:0045055"(regulated exocytosis)|go:"GO:0045684"(positive regulation of epidermis development)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070268"(cornification)|mint:Q9BSE2|refseq:NP_115699.1|entrezgene/locuslink:84283(identity)	refseq:NP_015507.1|sgd:S000006385|ensemblfungi:YPR181C(gene)|ensemblfungi:YPR181C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003400"(regulation of COPII vesicle coating)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016236"(macroautophagy)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0061709"(reticulophagy)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:0090110"(COPII-coated vesicle cargo loading)|interpro:IPR006895(Zinc finger, Sec23/Sec24-type)|interpro:IPR006896(Sec23/Sec24 trunk region)|interpro:IPR006900(Sec23/Sec24 helical region)|interpro:IPR007123(Gelsolin region)|interpro:IPR012990(Sec23/Sec24 beta-sandwich)|interpro:IPR029006|interpro:IPR036174|interpro:IPR036175|interpro:IPR036180|interpro:IPR036465|interpro:IPR037364|interpro:IPR037550|rcsb pdb:1M2O|rcsb pdb:2QTV|rcsb pdb:4BZI|rcsb pdb:6GNI|rcsb pdb:6ZGA|reactome:R-SCE-204005|reactome:R-SCE-5694530|reactome:R-SCE-983170|rcsb pdb:1M2V|dip:DIP-2232N|mint:P15303|sgd:YPR181C(identity)	-	comment:mint	crc64:69811913848265FB	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:QdmILKEdTJzJUhBdigw/4vC4R3o9606	rogid:IqC3qOrbef6aMHBztUW5+7DZ4IQ559292	intact-crc:2D842D98AB248497|rigid:24mlGqSFa+DOaxDKtlfF/GK7GEg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P15732	uniprotkb:Q9Y4K3	intact:EBI-2097669|uniprotkb:D6VS45|ensemblfungi:YDR059C	intact:EBI-359276|uniprotkb:Q8NEH5|uniprotkb:A6NKI7|uniprotkb:A8KAB3|ensembl:ENSP00000337853|ensembl:ENSP00000433623|uniprotkb:D3DR16	psi-mi:ubc5_yeast(display_long)|uniprotkb:UBC5(gene name)|psi-mi:UBC5(display_short)|uniprotkb:Ubiquitin-protein ligase(gene name synonym)|uniprotkb:Ubiquitin carrier protein(gene name synonym)|uniprotkb:YD9609.13C(orf name)|uniprotkb:D4234(orf name)|uniprotkb:YDR059C(locus name)|uniprotkb:E2 ubiquitin-conjugating enzyme 5(gene name synonym)	psi-mi:traf6_human(display_long)|uniprotkb:TRAF6(gene name)|psi-mi:TRAF6(display_short)|uniprotkb:RNF85(gene name synonym)|uniprotkb:Interleukin-1 signal transducer(gene name synonym)|uniprotkb:RING finger protein 85(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase TRAF6(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRAF6(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11523475|imex:IM-24995-124	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010344.1|sgd:S000002466|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR023313|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|mint:P15732|ensemblfungi:YDR059C(gene)|ensemblfungi:YDR059C_mRNA(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034605"(cellular response to heat)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070628"(proteasome binding)|reactome:R-SCE-8866652|reactome:R-SCE-8866654|reactome:R-SCE-9033241|reactome:R-SCE-983168|sgd:YDR059C(identity)	refseq:NP_004611.1|refseq:NP_665802.1|ensembl:ENSG00000175104(gene)|ensembl:ENST00000348124(transcript)|ensembl:ENST00000526995(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001503"(ossification)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001843"(neural tube closure)|go:"GO:0002223"(stimulatory C-type lectin receptor signaling pathway)|go:"GO:0002637"(regulation of immunoglobulin production)|go:"GO:0002726"(positive regulation of T cell cytokine production)|go:"GO:0002753"(cytoplasmic pattern recognition receptor signaling pathway)|go:"GO:0002755"(MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007254"(JNK cascade)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030316"(osteoclast differentiation)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031666"(positive regulation of lipopolysaccharide-mediated signaling pathway)|go:"GO:0031996"(thioesterase binding)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035631"(CD40 receptor complex)|go:"GO:0038095"(Fc-epsilon receptor signaling pathway)|go:"GO:0042088"(T-helper 1 type immune response)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043011"(myeloid dendritic cell differentiation)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0045453"(bone resorption)|go:"GO:0045672"(positive regulation of osteoclast differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048468"(cell development)|go:"GO:0032813"(tumor necrosis factor receptor superfamily binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051865"(protein autoubiquitination)|interpro:IPR012227(TNF receptor-associated factor TRAF)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR027139|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070498"(interleukin-1-mediated signaling pathway)|interpro:IPR037309|interpro:IPR041310|interpro:IPR043211|mint:Q9Y4K3|rcsb pdb:1LB4|rcsb pdb:1LB5|go:"GO:0070534"(protein K63-linked ubiquitination)|rcsb pdb:1LB6|rcsb pdb:2ECI|rcsb pdb:2JMD|rcsb pdb:3HCS|rcsb pdb:3HCT|rcsb pdb:3HCU|rcsb pdb:4Z8M|rcsb pdb:5ZUJ|rcsb pdb:6A33|go:"GO:0070555"(response to interleukin-1)|rcsb pdb:7L3L|reactome:R-HSA-1257604|reactome:R-HSA-166058|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-205043|go:"GO:0071222"(cellular response to lipopolysaccharide)|reactome:R-HSA-209543|reactome:R-HSA-209560|reactome:R-HSA-2871837|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0097400"(interleukin-17-mediated signaling pathway)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1904996"(positive regulation of leukocyte adhesion to vascular endothelial cell)|go:"GO:2000679"(positive regulation of transcription regulatory region DNA binding)|interpro:IPR001293(Zinc finger, TRAF-type)|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-5607764|reactome:R-HSA-5689880|reactome:R-HSA-5689896|reactome:R-HSA-6811558|reactome:R-HSA-9014325|reactome:R-HSA-9020702|reactome:R-HSA-933541|reactome:R-HSA-933542|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-937042|reactome:R-HSA-937072|reactome:R-HSA-9645460|reactome:R-HSA-975110|reactome:R-HSA-975138|reactome:R-HSA-975144|reactome:R-HSA-975155|reactome:R-HSA-975163|reactome:R-HSA-975871|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|dip:DIP-27515N|entrezgene/locuslink:7189(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:lhkS9orGIZV1O+L0mEfzlpRvgtk559292	rogid:m0TTXwlrtXnnjXWbg0MsEULlq0I9606	intact-crc:2A26297E23863918|rigid:WyHHVlaKokHfqjsp56sg2/L1Sg8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P15732	uniprotkb:Q9UJV3-2	intact:EBI-2097669|uniprotkb:D6VS45|ensemblfungi:YDR059C	intact:EBI-10172526|ensembl:ENSP00000413976	psi-mi:ubc5_yeast(display_long)|uniprotkb:UBC5(gene name)|psi-mi:UBC5(display_short)|uniprotkb:Ubiquitin-protein ligase(gene name synonym)|uniprotkb:Ubiquitin carrier protein(gene name synonym)|uniprotkb:YD9609.13C(orf name)|uniprotkb:D4234(orf name)|uniprotkb:YDR059C(locus name)|uniprotkb:E2 ubiquitin-conjugating enzyme 5(gene name synonym)	psi-mi:q9ujv3-2(display_long)|uniprotkb:RING-type E3 ubiquitin transferase MID2(gene name synonym)|uniprotkb:FXY2(gene name synonym)|uniprotkb:Midin-2(gene name synonym)|uniprotkb:Midline defect 2(gene name synonym)|uniprotkb:Midline-2(gene name synonym)|uniprotkb:RING finger protein 60(gene name synonym)|uniprotkb:RNF60(gene name synonym)|uniprotkb:TRIM1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 1(gene name synonym)|uniprotkb:MID2(gene name)|psi-mi:MID2(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11523464|imex:IM-24995-123	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010344.1|sgd:S000002466|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR023313|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|mint:P15732|ensemblfungi:YDR059C(gene)|ensemblfungi:YDR059C_mRNA(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034605"(cellular response to heat)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070628"(proteasome binding)|reactome:R-SCE-8866652|reactome:R-SCE-8866654|reactome:R-SCE-9033241|reactome:R-SCE-983168|sgd:YDR059C(identity)	intact:EBI-751983(isoform-parent)|uniprotkb:Q9UJV3-2(isoform-parent)|ensembl:ENSG00000080561(gene)|ensembl:ENST00000443968(transcript)|entrezgene/locuslink:11043(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:lhkS9orGIZV1O+L0mEfzlpRvgtk559292	rogid:/FJ+V2H7SaWon7caUWkEkmHFVxQ9606	intact-crc:F2F2BC0903343DBB|rigid:7Oh3b3p86ZEAyVjJqseGj5X4AeE	false	-	sufficient binding region:21-705	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9HD26-2	uniprotkb:P15625	intact:EBI-11102276|ensembl:ENSP00000052569	intact:EBI-18678|uniprotkb:D6VTK8|ensemblfungi:YFL022C	psi-mi:q9hd26-2(display_long)|uniprotkb:GOPC(gene name)|psi-mi:GOPC(display_short)|uniprotkb:CAL(gene name synonym)|uniprotkb:CFTR-associated ligand(gene name synonym)|uniprotkb:FIG(gene name synonym)|uniprotkb:Fused in glioblastoma(gene name synonym)|uniprotkb:PDZ protein interacting specifically with TC10(gene name synonym)	psi-mi:syfa_yeast(display_long)|uniprotkb:FRS2(gene name)|psi-mi:FRS2(display_short)|uniprotkb:Phenylalanyl-tRNA synthetase alpha subunit(gene name synonym)|uniprotkb:YFL022C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11523423|imex:IM-24995-119	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000047932(gene)|ensembl:ENST00000052569(transcript)|intact:EBI-349832(isoform-parent)|uniprotkb:Q9HD26-2(isoform-parent)|entrezgene/locuslink:57120(identity)	refseq:NP_116631.1|sgd:S000001872|ensemblfungi:YFL022C(gene)|ensemblfungi:YFL022C_mRNA(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0002161"(aminoacyl-tRNA editing activity)|go:"GO:0004826"(phenylalanine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006432"(phenylalanyl-tRNA aminoacylation)|go:"GO:0009328"(phenylalanine-tRNA ligase complex)|interpro:IPR002319(Phenylalanyl-tRNA synthetase, class IIc)|interpro:IPR004529(Phenylalanyl-tRNA synthetase, class IIc, alpha subunit)|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR040586|interpro:IPR040725|dip:DIP-5428N|mint:P15625|sgd:YFL022C(identity)	-	-	crc64:50B7EAC675AB559B	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:QoEGY54FfmwTrpGVMQN9ASGPgVI9606	rogid:hOEtrjcfIHQLY9FwCDb3XI593A4559292	intact-crc:614237113637EE01|rigid:srErfDzAAmIU+g7YaBH+fja4yiM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P14373	uniprotkb:P15705	intact:EBI-719493|uniprotkb:A2BE15|uniprotkb:Q5RJA8|uniprotkb:Q5ST26|uniprotkb:Q6LA73|uniprotkb:Q6NXR9|uniprotkb:Q9BZY6|uniprotkb:Q9UJL3|ensembl:ENSP00000383555|ensembl:ENSP00000392787|ensembl:ENSP00000405229|ensembl:ENSP00000414793|ensembl:ENSP00000366404	intact:EBI-18418|uniprotkb:D6W293|ensemblfungi:YOR027W	psi-mi:tri27_human(display_long)|uniprotkb:TRIM27(gene name)|psi-mi:TRIM27(display_short)|uniprotkb:RNF76(gene name synonym)|uniprotkb:RFP(gene name synonym)|uniprotkb:Ret finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 27(gene name synonym)|uniprotkb:RING finger protein 76(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM27(gene name synonym)	psi-mi:sti1_yeast(display_long)|uniprotkb:STI1(gene name)|psi-mi:STI1(display_short)|uniprotkb:OR26.17(orf name)|uniprotkb:YOR027W(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11523441|imex:IM-24995-121	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006501.1|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0090281"(negative regulation of calcium ion import)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR020457|interpro:IPR035791|interpro:IPR043136|mint:P14373|reactome:R-HSA-3232142|reactome:R-HSA-9635465|reactome:R-HSA-8948751|ensembl:ENSG00000204713(gene)|ensembl:ENSG00000215641(gene)|ensembl:ENSG00000229006(gene)|ensembl:ENSG00000234495(gene)|ensembl:ENSG00000237071(gene)|ensembl:ENST00000377199(transcript)|ensembl:ENST00000400720(transcript)|ensembl:ENST00000431123(transcript)|ensembl:ENST00000435528(transcript)|ensembl:ENST00000437160(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001650"(fibrillar center)|go:"GO:0002820"(negative regulation of adaptive immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|entrezgene/locuslink:5987(identity)	refseq:NP_014670.1|sgd:S000005553|ensemblfungi:YOR027W(gene)|ensemblfungi:YOR027W_mRNA(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0008104"(protein localization)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0042030"(ATPase inhibitor activity)|go:"GO:0051879"(Hsp90 protein binding)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR041243|rcsb pdb:2LLV|rcsb pdb:2LLW|rcsb pdb:3UPV|rcsb pdb:3UQ3|reactome:R-SCE-3371497|reactome:R-SCE-9696273|dip:DIP-2329N|mint:P15705|sgd:YOR027W(identity)	-	-	crc64:CF8A85C2BBD3C44C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:dsfH5OUghD8KSaTz1SFw9OYVTK49606	rogid:+w2ibiXXPwvtcC3RxknGi0ELvvE559292	intact-crc:41540B4FDE50B8F6|rigid:/0f+kHMDtL8MhCjXJzxLlnLTMwo	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q16637	uniprotkb:P15646	intact:EBI-395421|uniprotkb:Q13119|uniprotkb:Q549U5|uniprotkb:Q96J51|ensembl:ENSP00000305857|uniprotkb:A8K0V4|ensembl:ENSP00000370083|ensembl:ENSP00000370117|ensembl:ENSP00000370119|ensembl:ENSP00000479920|ensembl:ENSP00000482966|ensembl:ENSP00000483515|ensembl:ENSP00000483819|ensembl:ENSP00000487206|ensembl:ENSP00000487421	intact:EBI-6838|uniprotkb:P89890|uniprotkb:D6VRX5|ensemblfungi:YDL014W	psi-mi:smn_human(display_long)|uniprotkb:SMN1(gene name)|psi-mi:SMN1(display_short)|uniprotkb:SMN(gene name synonym)|uniprotkb:SMNT(gene name synonym)|uniprotkb:SMN2(gene name)|psi-mi:SMN2(display_short)|uniprotkb:SMNC(gene name synonym)|uniprotkb:Component of gems 1(gene name synonym)|uniprotkb:Gemin-1(gene name synonym)	psi-mi:fbrl_yeast(display_long)|uniprotkb:NOP1(gene name)|psi-mi:NOP1(display_short)|uniprotkb:LOT3(gene name synonym)|uniprotkb:YDL014W(locus name)|uniprotkb:D2870(orf name)|uniprotkb:U3 small nucleolar RNA-associated protein NOP1(gene name synonym)|uniprotkb:Histone-glutamine methyltransferase(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11523432|imex:IM-24995-120	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000335.1|refseq:NP_059107.1|refseq:NP_075012.1|refseq:NP_075013.1|refseq:NP_075014.1|refseq:NP_075015.1|ensembl:ENSG00000172062(gene)|ensembl:ENSG00000205571(gene)|ensembl:ENSG00000273772(gene)|ensembl:ENSG00000275349(gene)|ensembl:ENSG00000277773(gene)|ensembl:ENST00000351205(transcript)|ensembl:ENST00000380707(transcript)|ensembl:ENST00000380741(transcript)|ensembl:ENST00000380743(transcript)|ensembl:ENST00000614610(transcript)|ensembl:ENST00000618251(transcript)|ensembl:ENST00000618661(transcript)|ensembl:ENST00000622739(transcript)|ensembl:ENST00000627341(transcript)|ensembl:ENST00000629122(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0007399"(nervous system development)|go:"GO:0015030"(Cajal body)|go:"GO:0016604"(nuclear body)|go:"GO:0030018"(Z disc)|go:"GO:0030424"(axon)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043204"(perikaryon)|go:"GO:0097504"(Gemini of coiled bodies)|interpro:IPR002999(Tudor)|interpro:IPR010304(Survival motor neuron)|mint:Q16637|rcsb pdb:1G5V|rcsb pdb:1MHN|rcsb pdb:2LEH|rcsb pdb:4A4E|rcsb pdb:4A4G|rcsb pdb:4GLI|rcsb pdb:4QQ6|rcsb pdb:5XJL|go:"GO:0034719"(SMN-Sm protein complex)|rcsb pdb:5XJQ|rcsb pdb:5XJR|rcsb pdb:5XJS|rcsb pdb:5XJT|rcsb pdb:5XJU|reactome:R-HSA-191859|go:"GO:0032797"(SMN complex)|refseq:NP_001284644.1|ensembl:ENSP00000305857|ensembl:ENSP00000370083|ensembl:ENSP00000370117|ensembl:ENST00000380742|ensembl:ENSP00000370118|ensembl:ENSP00000370119|ensembl:ENST00000503079|ensembl:ENSP00000428128|ensembl:ENST00000506163|ensembl:ENSP00000424926|ensembl:ENST00000611442|ensembl:ENSP00000483768|ensembl:ENST00000614240|ensembl:ENSP00000479279|ensembl:ENSP00000479920|ensembl:ENST00000614773|ensembl:ENSP00000481427|ensembl:ENSP00000483515|ensembl:ENSP00000483819|ensembl:ENST00000622158|ensembl:ENSP00000480906|ensembl:ENSP00000482966|ensembl:ENST00000624634|ensembl:ENSP00000485595|ensembl:ENST00000626847|ensembl:ENSP00000486152|ensembl:ENSP00000487421|ensembl:ENST00000628353|ensembl:ENSP00000487029|ensembl:ENST00000628642|ensembl:ENSP00000487015|ensembl:ENSP00000487206|refseq:XP_016865275.1|dip:DIP-31309N|entrezgene/locuslink:6607(identity)	refseq:NP_010270.1|sgd:S000002172|mint:P15646|dip:DIP-698N|ensemblfungi:YDL014W(gene)|ensemblfungi:YDL014W_mRNA(transcript)|go:"GO:0000451"(rRNA 2'-O-methylation)|go:"GO:0000494"(box C/D RNA 3'-end processing)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006356"(regulation of transcription by RNA polymerase I)|go:"GO:0006364"(rRNA processing)|go:"GO:0008171"(O-methyltransferase activity)|go:"GO:0008649"(rRNA methyltransferase activity)|go:"GO:0030686"(90S preribosome)|go:"GO:0031167"(rRNA methylation)|go:"GO:0031428"(box C/D RNP complex)|go:"GO:0032040"(small-subunit processome)|go:"GO:0043144"("sno(s)RNA processing")|go:"GO:1990258"(histone glutamine methylation)|go:"GO:1990259"(histone-glutamine methyltransferase activity)|interpro:IPR000692(Fibrillarin)|interpro:IPR020813|interpro:IPR029063|rcsb pdb:5WLC|rcsb pdb:5WYJ|rcsb pdb:5WYK|rcsb pdb:6KE6|rcsb pdb:6LQP|rcsb pdb:6LQQ|rcsb pdb:6LQR|rcsb pdb:6LQS|rcsb pdb:6LQT|rcsb pdb:6LQU|rcsb pdb:6LQV|rcsb pdb:6ND4|rcsb pdb:6ZDT|rcsb pdb:6ZQA|rcsb pdb:6ZQB|rcsb pdb:6ZQC|rcsb pdb:6ZQD|rcsb pdb:6ZQE|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-6791226|sgd:YDL014W(identity)	-	-	crc64:56A8B958A7B6066E	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:QGivm7E8suciCWXO4l0zCUzCl2g9606	rogid:zc81RbHf8PxId/8oPXPD3/MpmBU559292	intact-crc:E32D096520001879|rigid:lM0zfvKUz7wkBKJV2PFPNPJ+goI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P15732	uniprotkb:Q9HCM9-2	intact:EBI-2097669|uniprotkb:D6VS45|ensemblfungi:YDR059C	intact:EBI-11523450|ensembl:ENSP00000365847|ensembl:ENSP00000373095|ensembl:ENSP00000373097|ensembl:ENSP00000379797|ensembl:ENSP00000379800|ensembl:ENSP00000383486|ensembl:ENSP00000387445|ensembl:ENSP00000389198|ensembl:ENSP00000389852|ensembl:ENSP00000392130|ensembl:ENSP00000394353|ensembl:ENSP00000396986|ensembl:ENSP00000398956|ensembl:ENSP00000401071|ensembl:ENSP00000401184|ensembl:ENSP00000404340|ensembl:ENSP00000404904|ensembl:ENSP00000411582|ensembl:ENSP00000412743|ensembl:ENSP00000414525|ensembl:ENSP00000415259	psi-mi:ubc5_yeast(display_long)|uniprotkb:UBC5(gene name)|psi-mi:UBC5(display_short)|uniprotkb:Ubiquitin-protein ligase(gene name synonym)|uniprotkb:Ubiquitin carrier protein(gene name synonym)|uniprotkb:YD9609.13C(orf name)|uniprotkb:D4234(orf name)|uniprotkb:YDR059C(locus name)|uniprotkb:E2 ubiquitin-conjugating enzyme 5(gene name synonym)	psi-mi:q9hcm9-2(display_long)|uniprotkb:TRIM39(gene name)|psi-mi:TRIM39(display_short)|uniprotkb:RING finger protein 23(gene name synonym)|uniprotkb:RNF23(gene name synonym)|uniprotkb:TFP(gene name synonym)|uniprotkb:Testis-abundant finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 39(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM39(gene name synonym)|uniprotkb:TIM39beta(isoform synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11523454|imex:IM-24995-122	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010344.1|sgd:S000002466|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR023313|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|mint:P15732|ensemblfungi:YDR059C(gene)|ensemblfungi:YDR059C_mRNA(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034605"(cellular response to heat)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070628"(proteasome binding)|reactome:R-SCE-8866652|reactome:R-SCE-8866654|reactome:R-SCE-9033241|reactome:R-SCE-983168|sgd:YDR059C(identity)	intact:EBI-739510(isoform-parent)|ensembl:ENSG00000204599(gene)|ensembl:ENSG00000206495(gene)|ensembl:ENSG00000224994(gene)|ensembl:ENSG00000226437(gene)|ensembl:ENSG00000229929(gene)|ensembl:ENSG00000230308(gene)|ensembl:ENSG00000232839(gene)|ensembl:ENST00000376659(transcript)|ensembl:ENST00000383601(transcript)|ensembl:ENST00000383603(transcript)|ensembl:ENST00000396548(transcript)|ensembl:ENST00000396551(transcript)|ensembl:ENST00000400644(transcript)|ensembl:ENST00000414015(transcript)|ensembl:ENST00000419790(transcript)|ensembl:ENST00000430502(transcript)|ensembl:ENST00000431272(transcript)|ensembl:ENST00000433900(transcript)|ensembl:ENST00000438076(transcript)|ensembl:ENST00000438859(transcript)|ensembl:ENST00000440117(transcript)|ensembl:ENST00000443109(transcript)|ensembl:ENST00000446397(transcript)|ensembl:ENST00000449318(transcript)|ensembl:ENST00000450778(transcript)|ensembl:ENST00000451132(transcript)|ensembl:ENST00000452705(transcript)|ensembl:ENST00000458607(transcript)|uniprotkb:Q9HCM9-2(isoform-parent)|entrezgene/locuslink:56658(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:lhkS9orGIZV1O+L0mEfzlpRvgtk559292	rogid:UfSn2+IVRxtGomVeDGdZpL7mz5I9606	intact-crc:6B1494A93BB6CBFE|rigid:P6Z55egYY1Vj8JOem5y9wSpIWKA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P17157	uniprotkb:Q08379	intact:EBI-13327|uniprotkb:Q03089|uniprotkb:Q06888|ensemblfungi:YPL031C|uniprotkb:D6W3Y2	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	psi-mi:pho85_yeast(display_long)|uniprotkb:PHO85(gene name)|psi-mi:PHO85(display_short)|uniprotkb:SSG3(gene name synonym)|uniprotkb:P7102.18A(orf name)|uniprotkb:Serine/threonine-protein kinase PHO85(gene name synonym)|uniprotkb:Negative regulator of the PHO system(gene name synonym)|uniprotkb:YPL031C(locus name)	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11523539|imex:IM-24995-130	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015294.1|sgd:S000005952|ensemblfungi:YPL031C(gene)|ensemblfungi:YPL031C_mRNA(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016242"(negative regulation of macroautophagy)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032878"(regulation of establishment or maintenance of cell polarity)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045719"(negative regulation of glycogen biosynthetic process)|go:"GO:0045936"(negative regulation of phosphate metabolic process)|go:"GO:0046822"(regulation of nucleocytoplasmic transport)|go:"GO:0050849"(negative regulation of calcium-mediated signaling)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0005737"(cytoplasm)|rcsb pdb:2PK9|rcsb pdb:2PMI|rcsb pdb:4KRC|rcsb pdb:4KRD|go:"GO:0005634"(nucleus)|go:"GO:0071073"(positive regulation of phospholipid biosynthetic process)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901987"(regulation of cell cycle phase transition)|go:"GO:1990860"(Pho85-Pho80 CDK-cyclin complex)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P17157|dip:DIP-1493N|sgd:YPL031C(identity)	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N|entrezgene/locuslink:2801(identity)	-	crc64:246A4358870B00EC	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2017/05/26	rogid:hrRlpgrzGGTT3/GQ5x0LgsjaGeE559292	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	intact-crc:3B995AEB91543C08|rigid:yhUw4ej2ECe4hzP0ttntGIKK+bM	false	-	sufficient binding region:383-1002	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P16622	uniprotkb:Q13554-3	intact:EBI-8261|uniprotkb:D6W2N2|ensemblfungi:YOR176W	intact:EBI-11523526|ensembl:ENSP00000351542	psi-mi:hemh_yeast(display_long)|uniprotkb:YOR176W(locus name)|uniprotkb:HEM15(gene name)|psi-mi:HEM15(display_short)|uniprotkb:Protoheme ferro-lyase(gene name synonym)|uniprotkb:Heme synthase(gene name synonym)	psi-mi:q13554-3(display_long)|uniprotkb:CAMK2B(gene name)|psi-mi:CAMK2B(display_short)|uniprotkb:CAM2(gene name synonym)|uniprotkb:CAMK2(gene name synonym)|uniprotkb:CAMKB(gene name synonym)|uniprotkb:Beta'E(isoform synonym)|uniprotkb:Beta1(isoform synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11523530|imex:IM-24995-129	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005702|reactome:R-SCE-189451|refseq:NP_014819.3|dip:DIP-4133N|ensemblfungi:YOR176W(gene)|ensemblfungi:YOR176W_mRNA(transcript)|go:"GO:0004325"(ferrochelatase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006783"(heme biosynthetic process)|interpro:IPR001015(Ferrochelatase)|interpro:IPR019772|interpro:IPR033644|interpro:IPR033659|rcsb pdb:1L8X|rcsb pdb:1LBQ|sgd:YOR176W(identity)	ensembl:ENSG00000058404(gene)|ensembl:ENST00000358707(transcript)|intact:EBI-1058722(isoform-parent)|uniprotkb:Q13554-3(isoform-parent)|entrezgene/locuslink:816(identity)	-	crc64:F04E7C7AAD36C24F	isoform-comment:"Ref.1 (AAD42036) sequence is in conflict in position: 316:A->V."	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:XIsqmtBuj9oH1aN0DT4zEfQ7u9Q559292	rogid:H/SPSRbW/NRcHPJs7Z2y6ESTrhM9606	intact-crc:1ECCFCE935B7EFBB|rigid:N6Dnldxy/SX+NigiURwyH6sVW3M	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P15807	uniprotkb:Q8N0S2	intact:EBI-10770|ensemblfungi:YBR213W|uniprotkb:D6VQK9	intact:EBI-6872807|ensembl:ENSP00000341282|uniprotkb:Q9BWU4|uniprotkb:B2RC80|uniprotkb:Q9BWU3	psi-mi:met8_yeast(display_long)|uniprotkb:YBR1461(orf name)|uniprotkb:YBR213W(locus name)|uniprotkb:MET8(gene name)|psi-mi:MET8(display_short)	psi-mi:syce1_human(display_long)|uniprotkb:C10orf94(gene name synonym)|uniprotkb:Cancer/testis antigen 76(gene name synonym)|uniprotkb:SYCE1(gene name)|psi-mi:SYCE1(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11523484|imex:IM-24995-125	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YBR213W(gene)|ensemblfungi:YBR213W_mRNA(transcript)|go:"GO:0000103"(sulfate assimilation)|go:"GO:0004325"(ferrochelatase activity)|go:"GO:0019354"(siroheme biosynthetic process)|go:"GO:0043115"(precorrin-2 dehydrogenase activity)|go:"GO:0051266"(sirohydrochlorin ferrochelatase activity)|interpro:IPR028161|interpro:IPR028162|interpro:IPR028281|interpro:IPR036291|rcsb pdb:1KYQ|refseq:NP_009772.1|sgd:S000000417|mint:P15807|dip:DIP-4944N|sgd:YBR213W(identity)	ensembl:ENSG00000171772(gene)|ensembl:ENST00000343131(transcript)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0000801"(central element)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051301"(cell division)|interpro:IPR026676|reactome:R-HSA-1221632|refseq:NP_001137235.1|refseq:NP_570140.1|entrezgene/locuslink:93426(identity)	-	crc64:0EE9A6DE8A43673E	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:4Z2yZage0Yi6KB2YM/gANFSLcC0559292	rogid:qLVqIlFiwZJHFfoyYXV3jrqdd609606	intact-crc:362CA5F8878770A9|rigid:hD30oL8Wp0apbcFpk6VS7i9/3u4	false	-	sufficient binding region:37-351	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P15873	uniprotkb:P63279	intact:EBI-12993|uniprotkb:D6VQ89|ensemblfungi:YBR088C	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	psi-mi:pcna_yeast(display_long)|uniprotkb:YBR0811(orf name)|uniprotkb:YBR088C(locus name)|uniprotkb:POL30(gene name)|psi-mi:POL30(display_short)	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11523508|imex:IM-24995-127	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009645.1|sgd:S000000292|go:"GO:0043626"(PCNA complex)|go:"GO:0070987"(error-free translesion synthesis)|go:"GO:1902394"(positive regulation of exodeoxyribonuclease activity)|go:"GO:1903022"(positive regulation of phosphodiesterase activity, acting on 3'-phosphoglycolate-terminated DNA strands)|go:"GO:1905779"(positive regulation of exonuclease activity)|interpro:IPR000730(Proliferating cell nuclear antigen, PCNA)|interpro:IPR022648|interpro:IPR022649|interpro:IPR022659|rcsb pdb:1PLQ|rcsb pdb:1PLR|rcsb pdb:1SXJ|rcsb pdb:2OD8|rcsb pdb:3F1W|rcsb pdb:3GPM|rcsb pdb:3GPN|rcsb pdb:3L0W|rcsb pdb:4L6P|rcsb pdb:3L0X|rcsb pdb:3L10|rcsb pdb:4YHR|rcsb pdb:3PGE|rcsb pdb:3V60|rcsb pdb:3V61|rcsb pdb:3V62|rcsb pdb:5JNE|rcsb pdb:4L60|mint:P15873|dip:DIP-2417N|go:"GO:0035753"(maintenance of DNA trinucleotide repeats)|ensemblfungi:YBR088C(gene)|ensemblfungi:YBR088C_mRNA(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000710"(meiotic mismatch repair)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005657"(replication fork)|go:"GO:0006272"(leading strand elongation)|go:"GO:0006273"(lagging strand elongation)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006298"(mismatch repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0006348"|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0019985"(translesion synthesis)|go:"GO:0030337"(DNA polymerase processivity factor activity)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0034087"(establishment of mitotic sister chromatid cohesion)|go:"GO:0042802"(identical protein binding)|rcsb pdb:5T9D|rcsb pdb:5V7K|rcsb pdb:5V7M|rcsb pdb:5ZUT|rcsb pdb:6CX2|rcsb pdb:6CX3|rcsb pdb:6CX4|rcsb pdb:6D0Q|rcsb pdb:6D0R|rcsb pdb:6E49|rcsb pdb:6W9W|rcsb pdb:6WAC|reactome:R-SCE-110312|reactome:R-SCE-110320|reactome:R-SCE-4615885|reactome:R-SCE-5358565|reactome:R-SCE-5655862|reactome:R-SCE-5656121|reactome:R-SCE-5656169|reactome:R-SCE-6782135|reactome:R-SCE-69091|reactome:R-SCE-69166|reactome:R-SCE-69183|reactome:R-SCE-8866654|rcsb pdb:5V7L|sgd:YBR088C(identity)	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N|entrezgene/locuslink:7329(identity)	-	crc64:9B56C5851621DDDC	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:/+XSPV99OBBwBBC/nY0JiHaAeSI559292	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	intact-crc:BAEADE1F4B92D188|rigid:YdniTwKdzx3mimAIA3uHlEvBwf0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P15873	uniprotkb:P30260-2	intact:EBI-12993|uniprotkb:D6VQ89|ensemblfungi:YBR088C	intact:EBI-11523497|ensembl:ENSP00000434614	psi-mi:pcna_yeast(display_long)|uniprotkb:YBR0811(orf name)|uniprotkb:YBR088C(locus name)|uniprotkb:POL30(gene name)|psi-mi:POL30(display_short)	psi-mi:p30260-2(display_long)|uniprotkb:CDC27(gene name)|psi-mi:CDC27(display_short)|uniprotkb:ANAPC3(gene name synonym)|uniprotkb:Anaphase-promoting complex subunit 3(gene name synonym)|uniprotkb:CDC27 homolog(gene name synonym)|uniprotkb:D0S1430E(gene name synonym)|uniprotkb:D17S978E(gene name synonym)|uniprotkb:H-NUC(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11523495|imex:IM-24995-126	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009645.1|sgd:S000000292|go:"GO:0043626"(PCNA complex)|go:"GO:0070987"(error-free translesion synthesis)|go:"GO:1902394"(positive regulation of exodeoxyribonuclease activity)|go:"GO:1903022"(positive regulation of phosphodiesterase activity, acting on 3'-phosphoglycolate-terminated DNA strands)|go:"GO:1905779"(positive regulation of exonuclease activity)|interpro:IPR000730(Proliferating cell nuclear antigen, PCNA)|interpro:IPR022648|interpro:IPR022649|interpro:IPR022659|rcsb pdb:1PLQ|rcsb pdb:1PLR|rcsb pdb:1SXJ|rcsb pdb:2OD8|rcsb pdb:3F1W|rcsb pdb:3GPM|rcsb pdb:3GPN|rcsb pdb:3L0W|rcsb pdb:4L6P|rcsb pdb:3L0X|rcsb pdb:3L10|rcsb pdb:4YHR|rcsb pdb:3PGE|rcsb pdb:3V60|rcsb pdb:3V61|rcsb pdb:3V62|rcsb pdb:5JNE|rcsb pdb:4L60|mint:P15873|dip:DIP-2417N|go:"GO:0035753"(maintenance of DNA trinucleotide repeats)|ensemblfungi:YBR088C(gene)|ensemblfungi:YBR088C_mRNA(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000710"(meiotic mismatch repair)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005657"(replication fork)|go:"GO:0006272"(leading strand elongation)|go:"GO:0006273"(lagging strand elongation)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006298"(mismatch repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0006348"|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0019985"(translesion synthesis)|go:"GO:0030337"(DNA polymerase processivity factor activity)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0034087"(establishment of mitotic sister chromatid cohesion)|go:"GO:0042802"(identical protein binding)|rcsb pdb:5T9D|rcsb pdb:5V7K|rcsb pdb:5V7M|rcsb pdb:5ZUT|rcsb pdb:6CX2|rcsb pdb:6CX3|rcsb pdb:6CX4|rcsb pdb:6D0Q|rcsb pdb:6D0R|rcsb pdb:6E49|rcsb pdb:6W9W|rcsb pdb:6WAC|reactome:R-SCE-110312|reactome:R-SCE-110320|reactome:R-SCE-4615885|reactome:R-SCE-5358565|reactome:R-SCE-5655862|reactome:R-SCE-5656121|reactome:R-SCE-5656169|reactome:R-SCE-6782135|reactome:R-SCE-69091|reactome:R-SCE-69166|reactome:R-SCE-69183|reactome:R-SCE-8866654|rcsb pdb:5V7L|sgd:YBR088C(identity)	ensembl:ENSG00000004897(gene)|ensembl:ENST00000531206(transcript)|intact:EBI-994813(isoform-parent)|entrezgene/locuslink:996(identity)	-	crc64:9B56C5851621DDDC	isoform-comment:No experimental confirmation available. May be due to competing acceptor splice site.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:/+XSPV99OBBwBBC/nY0JiHaAeSI559292	rogid:/GhmGv1GqwYuwjZWyCXHEd5UN3M9606	intact-crc:6FBDF0CB0B9A4F4A|rigid:4EM3yzg8PzpDhnm9KhYccsP8+yo	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9NYB9-2	uniprotkb:P16523	intact:EBI-11096309|ensembl:ENSP00000261017	intact:EBI-10736|ensemblfungi:YNL210W|uniprotkb:D6W0Y0	psi-mi:q9nyb9-2(display_long)|uniprotkb:ABI2(gene name)|psi-mi:ABI2(display_short)|uniprotkb:ARGBPIA(gene name synonym)|uniprotkb:Abelson interactor 2(gene name synonym)|uniprotkb:Abl-binding protein 3(gene name synonym)|uniprotkb:Arg-binding protein 1(gene name synonym)	psi-mi:mer1_yeast(display_long)|uniprotkb:N1330(orf name)|uniprotkb:YNL210W(locus name)|uniprotkb:MER1(gene name)|psi-mi:MER1(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11523517|imex:IM-24995-128	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-743598(isoform-parent)|ensembl:ENSG00000138443(gene)|ensembl:ENST00000261017(transcript)|uniprotkb:Q9NYB9-2(isoform-parent)|entrezgene/locuslink:10152(identity)	ensemblfungi:YNL210W(gene)|ensemblfungi:YNL210W_mRNA(transcript)|go:"GO:0000280"(nuclear division)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005844"(polysome)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:1990446"(U1 snRNP binding)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR036612|refseq:NP_014189.1|sgd:S000005154|dip:DIP-1436N|sgd:YNL210W(identity)	-	-	crc64:D23EC9B4849D73BA	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:VNi9aUeavD8+CCi+n1DXS+7mmbs9606	rogid:z5sxL8DmpJlmKWc7u/shEOoJkrQ559292	intact-crc:961BEF36EDB81B6F|rigid:41Yb9vz0z9pMOt+GLAV4Yrjvdx4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P17214	uniprotkb:O14641	intact:EBI-6684|uniprotkb:Q05997|uniprotkb:D6VYN3|ensemblfungi:YLR233C	intact:EBI-740850|ensembl:ENSP00000005340|uniprotkb:Q53XM0|uniprotkb:D3DTN3	psi-mi:est1_yeast(display_long)|uniprotkb:EST1(gene name)|psi-mi:EST1(display_short)|uniprotkb:YLR233C(locus name)|uniprotkb:L8083.15(orf name)|uniprotkb:Ever shorter telomeres protein 1(gene name synonym)	psi-mi:dvl2_human(display_long)|uniprotkb:DSH homolog 2(gene name synonym)|uniprotkb:DVL2(gene name)|psi-mi:DVL2(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11523580|imex:IM-24995-134	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013334.1|sgd:S000004223|reactome:R-SCE-975957|dip:DIP-1306N|ensemblfungi:YLR233C(gene)|ensemblfungi:YLR233C_mRNA(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005730"(nucleolus)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0032210"(regulation of telomere maintenance via telomerase)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0071919"(G-quadruplex DNA formation)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR018834|interpro:IPR019458|sgd:YLR233C(identity)	refseq:NP_004413.1|ensembl:ENSG00000004975(gene)|ensembl:ENST00000005340(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005109"(frizzled binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0007507"(heart development)|go:"GO:0016235"(aggresome)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044340"(canonical Wnt signaling pathway involved in regulation of cell proliferation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0150012"(positive regulation of neuron projection arborization)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008341(Dishevelled-2 region)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:O14641|rcsb pdb:2REY|rcsb pdb:3CBX|rcsb pdb:3CBY|rcsb pdb:3CBZ|rcsb pdb:3CC0|rcsb pdb:4WIP|rcsb pdb:5LNP|rcsb pdb:5SUY|rcsb pdb:5SUZ|rcsb pdb:6IW3|rcsb pdb:6JCK|reactome:R-HSA-201681|reactome:R-HSA-201688|reactome:R-HSA-2028269|reactome:R-HSA-4086400|reactome:R-HSA-4608870|reactome:R-HSA-4641258|reactome:R-HSA-4641262|reactome:R-HSA-5099900|reactome:R-HSA-5368598|reactome:R-HSA-5663220|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9673324|ensembl:ENSP00000005340|dip:DIP-34433N|entrezgene/locuslink:1856(identity)	-	crc64:9CF552AFDA6BDEDE	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:hu3SMHhlU1yKF9bVHdYQucREmxQ559292	rogid:2Vdc8oRnT4Mz/j+EXQXrL3AszOc9606	intact-crc:96DDD8F33E4A1254|rigid:mkiA782rXN9MsNLHSrz90WSvBRE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P17214	intact:EBI-11523568	intact:EBI-6684|uniprotkb:Q05997|uniprotkb:D6VYN3|ensemblfungi:YLR233C	-	psi-mi:est1_yeast(display_long)|uniprotkb:EST1(gene name)|psi-mi:EST1(display_short)|uniprotkb:YLR233C(locus name)|uniprotkb:L8083.15(orf name)|uniprotkb:Ever shorter telomeres protein 1(gene name synonym)	psi-mi:nav2(display_short)|psi-mi:EBI-11523568(display_long)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11523571|imex:IM-24995-133	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013334.1|sgd:S000004223|reactome:R-SCE-975957|dip:DIP-1306N|ensemblfungi:YLR233C(gene)|ensemblfungi:YLR233C_mRNA(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005730"(nucleolus)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0032210"(regulation of telomere maintenance via telomerase)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0071919"(G-quadruplex DNA formation)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR018834|interpro:IPR019458|sgd:YLR233C(identity)	entrezgene/locuslink:89797(identity)	-	crc64:9CF552AFDA6BDEDE	no-uniprot-update:	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:hu3SMHhlU1yKF9bVHdYQucREmxQ559292	rogid:WyH5VrQlZ4x7Sr5Hd4ApJ74qrL49606	intact-crc:6770CB1BCA47FD88|rigid:J1SSoGLyVpnh58nSouQ0nL7cFuk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P17255	uniprotkb:P43355	intact:EBI-20245|uniprotkb:O74301|uniprotkb:Q9Y7W5|uniprotkb:D6VRG7|ensemblfungi:YDL185W	intact:EBI-740978|ensembl:ENSP00000349085|uniprotkb:O00346|uniprotkb:B2RC81	psi-mi:vata_yeast(display_long)|uniprotkb:VMA1(gene name)|psi-mi:VMA1(display_short)|uniprotkb:CLS8(gene name synonym)|uniprotkb:TFP1(gene name synonym)|uniprotkb:YDL185W(locus name)|uniprotkb:D1286(orf name)|uniprotkb:Vacuolar proton pump subunit A(gene name synonym)	psi-mi:maga1_human(display_long)|uniprotkb:MAGE-1 antigen(gene name synonym)|uniprotkb:Antigen MZ2-E(gene name synonym)|uniprotkb:Cancer/testis antigen 1.1(gene name synonym)|uniprotkb:MAGEA1(gene name)|psi-mi:MAGEA1(display_short)|uniprotkb:MAGE1(gene name synonym)|uniprotkb:MAGE1A(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11523589|imex:IM-24995-135	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010096.1|sgd:S000002344|mint:P17255|ensemblfungi:YDL185W(gene)|ensemblfungi:YDL185W_mRNA(transcript)|go:"GO:0000221"(vacuolar proton-transporting V-type ATPase, V1 domain)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0003677"(DNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006314"(intron homing)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0012505"(endomembrane system)|go:"GO:0016539"(intein-mediated protein splicing)|go:"GO:0044267"(cellular protein metabolic process)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR003586(Hedgehog/intein hint domain, C-terminal)|interpro:IPR003587(Hedgehog/intein hint, N-terminal)|interpro:IPR004042(Intein DOD homing endonuclease)|interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR006141(Intein splicing site)|interpro:IPR006142(Intein)|interpro:IPR007868(Hom-end-associated Hint)|interpro:IPR007869(Homing endonuclease)|interpro:IPR020003|interpro:IPR022878|interpro:IPR023366|interpro:IPR027417|interpro:IPR027434|interpro:IPR030934|interpro:IPR031686|interpro:IPR036121|interpro:IPR036844|rcsb pdb:1DFA|rcsb pdb:1EF0|rcsb pdb:1GPP|rcsb pdb:1JVA|rcsb pdb:1LWS|rcsb pdb:1LWT|rcsb pdb:1UM2|rcsb pdb:1VDE|rcsb pdb:3J9T|rcsb pdb:3J9U|rcsb pdb:3J9V|rcsb pdb:5BW9|rcsb pdb:5D80|rcsb pdb:5VOX|rcsb pdb:5VOY|rcsb pdb:5VOZ|reactome:R-SCE-1222556|reactome:R-SCE-77387|reactome:R-SCE-917977|reactome:R-SCE-9639288|interpro:IPR024034|dip:DIP-2293N|sgd:YDL185W(identity)	refseq:NP_004979.3|ensembl:ENSG00000198681(gene)|ensembl:ENST00000356661(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|interpro:IPR002190(MAGE protein)|interpro:IPR021072|interpro:IPR030093|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|rcsb pdb:1W72|rcsb pdb:3BO8|dip:DIP-54794N|entrezgene/locuslink:4100(identity)	-	crc64:2A4C65D2F59426FD	crc64:544EEB1F9F4E9D33	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:YdmGZxIMX2IXMHC4EO85uOAf1Hg559292	rogid:6XW3mnTNM3yvOtXmiFbU8Uz3hjA9606	intact-crc:BBD45E79185AEFA5|rigid:eU2IYpxCFkXgEheF4T+xo6dsyI0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O96006	uniprotkb:P17157	intact:EBI-740037|uniprotkb:Q96BY4|ensembl:ENSP00000370616|ensembl:ENSP00000370620|ensembl:ENSP00000370621|ensembl:ENSP00000498725	intact:EBI-13327|uniprotkb:Q03089|uniprotkb:Q06888|ensemblfungi:YPL031C|uniprotkb:D6W3Y2	psi-mi:zbed1_human(display_long)|uniprotkb:ZBED1(gene name)|psi-mi:ZBED1(display_short)|uniprotkb:ALTE(gene name synonym)|uniprotkb:DREF(gene name synonym)|uniprotkb:KIAA0785(gene name synonym)|uniprotkb:TRAMP(gene name synonym)|uniprotkb:dREF homolog(gene name synonym)|uniprotkb:Putative Ac-like transposable element(gene name synonym)|uniprotkb:DNA replication-related element-binding factor(gene name synonym)|uniprotkb:Zinc finger BED domain-containing protein 1(gene name synonym)|uniprotkb:hDREF(gene name synonym)	psi-mi:pho85_yeast(display_long)|uniprotkb:PHO85(gene name)|psi-mi:PHO85(display_short)|uniprotkb:SSG3(gene name synonym)|uniprotkb:P7102.18A(orf name)|uniprotkb:Serine/threonine-protein kinase PHO85(gene name synonym)|uniprotkb:Negative regulator of the PHO system(gene name synonym)|uniprotkb:YPL031C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11523550|imex:IM-24995-131	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164606.1|refseq:NP_001164607.1|refseq:NP_004720.1|ensembl:ENSG00000214717(gene)|ensembl:ENST00000381218(transcript)|ensembl:ENST00000381222(transcript)|ensembl:ENST00000381223(transcript)|ensembl:ENST00000652001(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0031965"(nuclear membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044828"(negative regulation by host of viral genome replication)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0061665"(SUMO ligase activity)|go:"GO:1990466"(protein autosumoylation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003656(Zinc finger, BED-type predicted)|interpro:IPR008906(HAT dimerisation)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR036236|mint:O96006|rcsb pdb:2CT5|reactome:R-HSA-4551638|go:"GO:0005813"(centrosome)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016605"(PML body)|entrezgene/locuslink:9189(identity)	refseq:NP_015294.1|sgd:S000005952|ensemblfungi:YPL031C(gene)|ensemblfungi:YPL031C_mRNA(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016242"(negative regulation of macroautophagy)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032878"(regulation of establishment or maintenance of cell polarity)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045719"(negative regulation of glycogen biosynthetic process)|go:"GO:0045936"(negative regulation of phosphate metabolic process)|go:"GO:0046822"(regulation of nucleocytoplasmic transport)|go:"GO:0050849"(negative regulation of calcium-mediated signaling)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0005737"(cytoplasm)|rcsb pdb:2PK9|rcsb pdb:2PMI|rcsb pdb:4KRC|rcsb pdb:4KRD|go:"GO:0005634"(nucleus)|go:"GO:0071073"(positive regulation of phospholipid biosynthetic process)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901987"(regulation of cell cycle phase transition)|go:"GO:1990860"(Pho85-Pho80 CDK-cyclin complex)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P17157|dip:DIP-1493N|sgd:YPL031C(identity)	-	-	crc64:246A4358870B00EC	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:jl97ZV2Kz5YAmQKktWt/wk7OkRw9606	rogid:hrRlpgrzGGTT3/GQ5x0LgsjaGeE559292	intact-crc:BC2AE3738A473FAE|rigid:bv1kpjcMnZ71+67yBuT1w6rQrXM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9NSC5	uniprotkb:P17157	intact:EBI-748420|uniprotkb:O14580|uniprotkb:O95350|uniprotkb:Q9NSB9|uniprotkb:Q9NSC0|intact:EBI-2557809|uniprotkb:E9PCW9|uniprotkb:Q9NSC1|intact:EBI-28972925|ensembl:ENSP00000376162|ensembl:ENSP00000439937|ensembl:ENSP00000446026|intact:EBI-10175777|uniprotkb:B2RA10	intact:EBI-13327|uniprotkb:Q03089|uniprotkb:Q06888|ensemblfungi:YPL031C|uniprotkb:D6W3Y2	psi-mi:home3_human(display_long)|uniprotkb:HOMER3(gene name)|psi-mi:HOMER3(display_short)	psi-mi:pho85_yeast(display_long)|uniprotkb:PHO85(gene name)|psi-mi:PHO85(display_short)|uniprotkb:SSG3(gene name synonym)|uniprotkb:P7102.18A(orf name)|uniprotkb:Serine/threonine-protein kinase PHO85(gene name synonym)|uniprotkb:Negative regulator of the PHO system(gene name synonym)|uniprotkb:YPL031C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11523559|imex:IM-24995-132	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000221222|ensembl:ENSP00000221222|ensembl:ENSP00000376162|ensembl:ENST00000433218|ensembl:ENSP00000396154|ensembl:ENSP00000439937|ensembl:ENSP00000446026|ensembl:ENST00000594439|ensembl:ENSP00000471835|refseq:XP_006723006.1|refseq:XP_006723007.1|refseq:NP_001139193.1|refseq:NP_001139194.1|refseq:NP_004829.3|refseq:NP_001139196.1|ensembl:ENSG00000051128(gene)|ensembl:ENST00000392351(transcript)|ensembl:ENST00000539827(transcript)|ensembl:ENST00000542541(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006605"(protein targeting)|go:"GO:0007216"(G protein-coupled glutamate receptor signaling pathway)|go:"GO:0014069"(postsynaptic density)|go:"GO:0030425"(dendrite)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0035256"(G protein-coupled glutamate receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|go:"GO:2001256"(regulation of store-operated calcium entry)|interpro:IPR000697(EVH1)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR044100|mint:Q9NSC5|rcsb pdb:2P8V|rcsb pdb:3CVF|reactome:R-HSA-6794361|entrezgene/locuslink:9454(identity)	refseq:NP_015294.1|sgd:S000005952|ensemblfungi:YPL031C(gene)|ensemblfungi:YPL031C_mRNA(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016242"(negative regulation of macroautophagy)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032878"(regulation of establishment or maintenance of cell polarity)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045719"(negative regulation of glycogen biosynthetic process)|go:"GO:0045936"(negative regulation of phosphate metabolic process)|go:"GO:0046822"(regulation of nucleocytoplasmic transport)|go:"GO:0050849"(negative regulation of calcium-mediated signaling)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0005737"(cytoplasm)|rcsb pdb:2PK9|rcsb pdb:2PMI|rcsb pdb:4KRC|rcsb pdb:4KRD|go:"GO:0005634"(nucleus)|go:"GO:0071073"(positive regulation of phospholipid biosynthetic process)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901987"(regulation of cell cycle phase transition)|go:"GO:1990860"(Pho85-Pho80 CDK-cyclin complex)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P17157|dip:DIP-1493N|sgd:YPL031C(identity)	-	-	crc64:246A4358870B00EC	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:U1y/y52nnf7zQUCNQlqk7JDgXi49606	rogid:hrRlpgrzGGTT3/GQ5x0LgsjaGeE559292	intact-crc:379D70BCDAF866AB|rigid:t1O3hmM+iD7DreqbG4upHbUR+uI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q6RW13-2	uniprotkb:P18496	intact:EBI-11522760|ensembl:ENSP00000365816	intact:EBI-3323|uniprotkb:Q06020|uniprotkb:D6VZ28|ensemblfungi:YLR393W	psi-mi:q6rw13-2(display_long)|uniprotkb:AGTRAP(gene name)|psi-mi:AGTRAP(display_short)|uniprotkb:AT1 receptor-associated protein(gene name synonym)|uniprotkb:ATRAP(gene name synonym)	psi-mi:atp10_yeast(display_long)|uniprotkb:ATP10(gene name)|psi-mi:ATP10(display_short)|uniprotkb:L8084.8(orf name)|uniprotkb:YLR393W(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11523647|imex:IM-24995-141	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000177674(gene)|ensembl:ENST00000376629(transcript)|intact:EBI-741181(isoform-parent)|uniprotkb:Q6RW13-2(isoform-parent)|entrezgene/locuslink:57085(identity)	refseq:NP_013497.1|sgd:S000004385|dip:DIP-4641N|ensemblfungi:YLR393W(gene)|ensemblfungi:YLR393W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0032592"(integral component of mitochondrial membrane)|go:"GO:0033615"(mitochondrial proton-transporting ATP synthase complex assembly)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR007849(ATP10)|sgd:YLR393W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:PNzVis/8puQZBJ562gCqZKc078s9606	rogid:3LfbKFFgOegWNYA+M/jOd0ORiAk559292	intact-crc:6A8939E2ECA51E07|rigid:RjK1ml/F9cQO92ApAhPt9NTHlcc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P17967	uniprotkb:Q9Y6N9-4	intact:EBI-13012|uniprotkb:D6VQX3|ensemblfungi:YCL043C	intact:EBI-11523636|ensembl:ENSP00000436934	psi-mi:pdi_yeast(display_long)|uniprotkb:TRG1(gene name synonym)|uniprotkb:YCL313(orf name)|uniprotkb:PDI1(gene name)|psi-mi:PDI1(display_short)|uniprotkb:MFP1(gene name synonym)|uniprotkb:Thioredoxin-related glycoprotein 1(gene name synonym)|uniprotkb:YCL43C(orf name)|uniprotkb:YCL043C(locus name)	psi-mi:q9y6n9-4(display_long)|uniprotkb:USH1C(gene name)|psi-mi:USH1C(display_short)|uniprotkb:AIE75(gene name synonym)|uniprotkb:Antigen NY-CO-38/NY-CO-37(gene name synonym)|uniprotkb:Autoimmune enteropathy-related antigen AIE-75(gene name synonym)|uniprotkb:Protein PDZ-73(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-3(gene name synonym)|uniprotkb:Usher syndrome type-1C protein(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11523634|imex:IM-24995-140	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009887.1|sgd:S000000548|mint:P17967|dip:DIP-4978N|ensemblfungi:YCL043C(gene)|ensemblfungi:YCL043C_mRNA(transcript)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006457"(protein folding)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0036508"(protein alpha-1,2-demannosylation)|go:"GO:0051082"(unfolded protein binding)|go:"GO:1904382"(mannose trimming involved in glycoprotein ERAD pathway)|interpro:IPR005792(Protein disulphide isomerase)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017937|interpro:IPR036249|rcsb pdb:2B5E|rcsb pdb:3BOA|reactome:R-SCE-901042|sgd:YCL043C(identity)	ensembl:ENSG00000006611(gene)|ensembl:ENST00000527020(transcript)|intact:EBI-954308(isoform-parent)|uniprotkb:Q9Y6N9-4(isoform-parent)|entrezgene/locuslink:10083(identity)	-	crc64:69CF3E05D7F74C94	isoform-comment:No experimental confirmation available.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:tyy52cf76yr9hl+9ggGGS4zDO/A559292	rogid:lC4fbXfsFOZFtutcdQYHSWpgcJY9606	intact-crc:C4241C5353D81E41|rigid:O5OTQq4ev081rwavpiPaYwg+7MA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P63279	uniprotkb:P17423	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	intact:EBI-9685|ensemblfungi:YHR025W|uniprotkb:D3DKX2	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:khse_yeast(display_long)|uniprotkb:THR1(gene name)|psi-mi:THR1(display_short)|uniprotkb:YHR025W(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11523598|imex:IM-24995-136	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N|entrezgene/locuslink:7329(identity)	ensemblfungi:YHR025W(gene)|ensemblfungi:YHR025W_mRNA(transcript)|go:"GO:0004413"(homoserine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0009088"(threonine biosynthetic process)|go:"GO:0009092"(homoserine metabolic process)|interpro:IPR000870(Homoserine kinase)|interpro:IPR006203(GHMP kinase, ATP-binding, conserved site)|interpro:IPR006204(GHMP kinase)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR020568|interpro:IPR036554|refseq:NP_011890.1|sgd:S000001067|dip:DIP-4305N|mint:P17423|sgd:YHR025W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	rogid:S6tiEUJn7YZY4ydBnYraAdecCRY559292	intact-crc:680C3FCD64B8FAB0|rigid:KOg4s/9QXLC+PzaNW9zzYbldD3A	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P17695	uniprotkb:Q96EQ0	intact:EBI-7699|uniprotkb:Q6B234|uniprotkb:D6VTD4|ensemblfungi:YDR513W	intact:EBI-744081|ensembl:ENSP00000370395	psi-mi:glrx2_yeast(display_long)|uniprotkb:TTR(gene name synonym)|uniprotkb:GRX2(gene name)|psi-mi:GRX2(display_short)|uniprotkb:Thioltransferase(gene name synonym)|uniprotkb:Glutathione-dependent oxidoreductase 2(gene name synonym)|uniprotkb:TTR1(gene name synonym)|uniprotkb:D9719.17(orf name)|uniprotkb:YDR513W(locus name)	psi-mi:sgtb_human(display_long)|uniprotkb:Beta-SGT(gene name synonym)|uniprotkb:Small glutamine-rich protein with tetratricopeptide repeats 2(gene name synonym)|uniprotkb:SGTB(gene name)|psi-mi:SGTB(display_short)|uniprotkb:SGT2(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11523616|imex:IM-24995-138	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010801.1|sgd:S000002921|dip:DIP-5271N|ensemblfungi:YDR513W(gene)|ensemblfungi:YDR513W_mRNA(transcript)|go:"GO:0004362"("glutathione-disulfide reductase (NADPH) activity")|go:"GO:0004364"(glutathione transferase activity)|go:"GO:0004602"(glutathione peroxidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0015036"(disulfide oxidoreductase activity)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0097573"(glutathione oxidoreductase activity)|interpro:IPR002109(Glutaredoxin)|interpro:IPR011767(Glutaredoxin active site)|interpro:IPR011899(Glutaredoxin, eukaryotic and viruses)|interpro:IPR014025(Glutaredoxin subgroup)|interpro:IPR036249|rcsb pdb:3CTF|rcsb pdb:3CTG|rcsb pdb:3D4M|rcsb pdb:3D5J|sgd:YDR513W(identity)	refseq:NP_061945.1|refseq:XP_005248605.1|ensembl:ENSG00000197860(gene)|ensembl:ENST00000381007(transcript)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0072380"(TRC complex)|go:"GO:1903646"(positive regulation of chaperone-mediated protein folding)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR032374|entrezgene/locuslink:54557(identity)	-	crc64:99A79B87695B2266	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:u4CcRMaG3tJhhzqf3yNKktvKfv4559292	rogid:emIgH8U/yVmXT00Ty9yybIqQqas9606	intact-crc:2323D5CB2966D7E4|rigid:UOpuro/yb07aRANWDzKKbv6TiI8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P17695	uniprotkb:O43765	intact:EBI-7699|uniprotkb:Q6B234|uniprotkb:D6VTD4|ensemblfungi:YDR513W	intact:EBI-347996|ensembl:ENSP00000221566|ensembl:ENSP00000503397|ensembl:ENSP00000504495|uniprotkb:Q9BTZ9|intact:EBI-1045243|uniprotkb:Q6FIA9|uniprotkb:D6W610	psi-mi:glrx2_yeast(display_long)|uniprotkb:TTR(gene name synonym)|uniprotkb:GRX2(gene name)|psi-mi:GRX2(display_short)|uniprotkb:Thioltransferase(gene name synonym)|uniprotkb:Glutathione-dependent oxidoreductase 2(gene name synonym)|uniprotkb:TTR1(gene name synonym)|uniprotkb:D9719.17(orf name)|uniprotkb:YDR513W(locus name)	psi-mi:sgta_human(display_long)|uniprotkb:SGTA(gene name)|psi-mi:SGTA(display_short)|uniprotkb:SGT(gene name synonym)|uniprotkb:Alpha-SGT(gene name synonym)|uniprotkb:Vpu-binding protein(gene name synonym)|uniprotkb:SGT1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11523607|imex:IM-24995-137	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010801.1|sgd:S000002921|dip:DIP-5271N|ensemblfungi:YDR513W(gene)|ensemblfungi:YDR513W_mRNA(transcript)|go:"GO:0004362"("glutathione-disulfide reductase (NADPH) activity")|go:"GO:0004364"(glutathione transferase activity)|go:"GO:0004602"(glutathione peroxidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0015036"(disulfide oxidoreductase activity)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0097573"(glutathione oxidoreductase activity)|interpro:IPR002109(Glutaredoxin)|interpro:IPR011767(Glutaredoxin active site)|interpro:IPR011899(Glutaredoxin, eukaryotic and viruses)|interpro:IPR014025(Glutaredoxin subgroup)|interpro:IPR036249|rcsb pdb:3CTF|rcsb pdb:3CTG|rcsb pdb:3D4M|rcsb pdb:3D5J|sgd:YDR513W(identity)	rcsb pdb:4CPG|rcsb pdb:4GOD|rcsb pdb:4GOE|rcsb pdb:4GOF|reactome:R-HSA-9609523|rcsb pdb:2VYI|ensembl:ENSG00000104969(gene)|ensembl:ENST00000221566(transcript)|ensembl:ENST00000676943(transcript)|ensembl:ENST00000677149(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072380"(TRC complex)|go:"GO:0098850"(extrinsic component of synaptic vesicle membrane)|go:"GO:1903070"(negative regulation of ER-associated ubiquitin-dependent protein catabolic process)|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)|go:"GO:1903646"(positive regulation of chaperone-mediated protein folding)|go:"GO:1904288"(BAT3 complex binding)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR032374|mint:O43765|refseq:XP_011526480.1|refseq:NP_003012.1|entrezgene/locuslink:6449(identity)	-	crc64:99A79B87695B2266	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:u4CcRMaG3tJhhzqf3yNKktvKfv4559292	rogid:r/Cyj4UJk/cS8QdrbjhTZMPCigI9606	intact-crc:2FBC785213DCD0E6|rigid:UrLJNS0V1U9lTAQcdJO0Z/NX+X0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q14145	uniprotkb:P17709	intact:EBI-751001|uniprotkb:B3KPD5|uniprotkb:Q8WTX1|uniprotkb:Q6LEP0|uniprotkb:Q9BPY9|intact:EBI-28976014|ensembl:ENSP00000171111|ensembl:ENSP00000377245	intact:EBI-8744|ensemblfungi:YCL040W|uniprotkb:D6VQX5	psi-mi:keap1_human(display_long)|uniprotkb:Cytosolic inhibitor of Nrf2(gene name synonym)|uniprotkb:Kelch-like protein 19(gene name synonym)|uniprotkb:KEAP1(gene name)|psi-mi:KEAP1(display_short)|uniprotkb:INRF2(gene name synonym)|uniprotkb:KIAA0132(gene name synonym)|uniprotkb:KLHL19(gene name synonym)	psi-mi:hxkg_yeast(display_long)|uniprotkb:GLK1(gene name)|psi-mi:GLK1(display_short)|uniprotkb:HOR3(gene name synonym)|uniprotkb:YCL040W(locus name)|uniprotkb:YCL40W(orf name)|uniprotkb:YCL312(orf name)|uniprotkb:Glucose kinase 1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11523625|imex:IM-24995-139	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_036421.2|refseq:NP_987096.1|ensembl:ENSP00000171111|ensembl:ENSP00000377245|refseq:XP_011526754.1|refseq:XP_005260230.1|refseq:XP_005260231.1|dip:DIP-42134N|ensembl:ENSG00000079999(gene)|ensembl:ENST00000171111(transcript)|ensembl:ENST00000393623(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0016234"(inclusion body)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030496"(midbody)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0034451"(centriolar satellite)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045604"(regulation of epidermal cell differentiation)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR017096(Kelch-like protein, gigaxonin)|interpro:IPR030563|mint:Q14145|rcsb pdb:1U6D|rcsb pdb:1ZGK|rcsb pdb:2FLU|rcsb pdb:3VNG|rcsb pdb:3VNH|rcsb pdb:3ZGC|rcsb pdb:3ZGD|rcsb pdb:4CXI|rcsb pdb:4CXJ|rcsb pdb:4CXT|rcsb pdb:4IFJ|rcsb pdb:4IFL|rcsb pdb:4IFN|rcsb pdb:4IN4|rcsb pdb:4IQK|rcsb pdb:4L7B|rcsb pdb:4L7C|rcsb pdb:4L7D|rcsb pdb:4N1B|rcsb pdb:4XMB|rcsb pdb:5DAD|rcsb pdb:5DAF|rcsb pdb:5F72|rcsb pdb:5GIT|rcsb pdb:5NLB|rcsb pdb:5WFL|rcsb pdb:5WFV|rcsb pdb:5WG1|rcsb pdb:5WHL|rcsb pdb:5WHO|rcsb pdb:5WIY|rcsb pdb:5X54|rcsb pdb:6FFM|rcsb pdb:6FMP|rcsb pdb:6FMQ|rcsb pdb:6HWS|rcsb pdb:6LRZ|rcsb pdb:6ROG|rcsb pdb:6SP1|rcsb pdb:6SP4|rcsb pdb:6T7V|rcsb pdb:6T7Z|rcsb pdb:6TG8|rcsb pdb:6TYM|rcsb pdb:6TYP|rcsb pdb:6UF0|rcsb pdb:6W66|rcsb pdb:6W67|rcsb pdb:6W68|rcsb pdb:6W69|rcsb pdb:6WCQ|rcsb pdb:6Z6A|rcsb pdb:7K28|rcsb pdb:7K29|rcsb pdb:7K2A|rcsb pdb:7K2B|rcsb pdb:7K2C|rcsb pdb:7K2D|rcsb pdb:7K2E|rcsb pdb:7K2F|rcsb pdb:7K2G|rcsb pdb:7K2H|rcsb pdb:7K2I|rcsb pdb:7K2J|rcsb pdb:7K2K|rcsb pdb:7K2L|rcsb pdb:7K2M|rcsb pdb:7K2N|rcsb pdb:7K2O|rcsb pdb:7K2P|rcsb pdb:7K2Q|rcsb pdb:7K2R|rcsb pdb:7K2S|reactome:R-HSA-5689880|reactome:R-HSA-8932339|reactome:R-HSA-8951664|reactome:R-HSA-983168|rcsb pdb:6V6Z|entrezgene/locuslink:9817(identity)	rcsb pdb:6PDT|reactome:R-SCE-170822|reactome:R-SCE-6798695|reactome:R-SCE-70171|go:"GO:0005536"(glucose binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006013"(mannose metabolic process)|go:"GO:0006096"(glycolytic process)|go:"GO:0008865"(fructokinase activity)|go:"GO:0019158"(mannokinase activity)|go:"GO:0046323"(glucose import)|go:"GO:0051156"(glucose 6-phosphate metabolic process)|interpro:IPR001312(Hexokinase)|interpro:IPR019807|interpro:IPR022672|interpro:IPR022673|interpro:IPR043129|rcsb pdb:6P4X|ensemblfungi:YCL040W(gene)|ensemblfungi:YCL040W_mRNA(transcript)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0004340"(glucokinase activity)|go:"GO:0005524"(ATP binding)|refseq:NP_009890.1|sgd:S000000545|mint:P17709|dip:DIP-525N|sgd:YCL040W(identity)	-	-	crc64:A7A417041D7A961F	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:3y/KqnUK+5nIyjhOEfkkthmP1OA9606	rogid:r6qkUttc6MTLWY6RYa26ZBCw2zg559292	intact-crc:4DB3BC086C082A54|rigid:YG4NPEf1kZrlg9Su05LxmqNqT0s	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P31153	uniprotkb:P19358	intact:EBI-1050743|uniprotkb:Q53SP5|uniprotkb:A8K511|uniprotkb:D6W5L1|ensembl:ENSP00000303147|uniprotkb:B4DN45	intact:EBI-10795|uniprotkb:E9P927|ensemblfungi:YDR502C|uniprotkb:D6VTC4	psi-mi:metk2_human(display_long)|uniprotkb:Methionine adenosyltransferase 2(gene name synonym)|uniprotkb:Methionine adenosyltransferase II(gene name synonym)|uniprotkb:MAT2A(gene name)|psi-mi:MAT2A(display_short)|uniprotkb:AMS2(gene name synonym)|uniprotkb:MATA2(gene name synonym)	psi-mi:metk2_yeast(display_long)|uniprotkb:SAM2(gene name)|psi-mi:SAM2(display_short)|uniprotkb:ETH2(gene name synonym)|uniprotkb:YDR502C(locus name)|uniprotkb:D9719.8(orf name)|uniprotkb:Methionine adenosyltransferase 2(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11523692|imex:IM-24995-146	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005902.1|rcsb pdb:5A1G|rcsb pdb:5A1I|rcsb pdb:5UGH|rcsb pdb:6FAJ|rcsb pdb:6FBN|rcsb pdb:6FBO|rcsb pdb:6FBP|rcsb pdb:6FCB|rcsb pdb:6FCD|rcsb pdb:6FWB|ensembl:ENSG00000168906(gene)|ensembl:ENST00000306434(transcript)|go:"GO:0004478"(methionine adenosyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006556"(S-adenosylmethionine biosynthetic process)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0034214"(protein hexamerization)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048269"(methionine adenosyltransferase complex)|go:"GO:0051291"(protein heterooligomerization)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR002133(S-adenosylmethionine synthetase)|rcsb pdb:6G6R|rcsb pdb:6P9V|rcsb pdb:6WKB|interpro:IPR022628|rcsb pdb:7BHR|rcsb pdb:7BHS|interpro:IPR022629|interpro:IPR022630|interpro:IPR022631|interpro:IPR022636|mint:P31153|rcsb pdb:2P02|rcsb pdb:4KTT|rcsb pdb:4KTV|rcsb pdb:4NDN|rcsb pdb:5A19|rcsb pdb:7BHT|rcsb pdb:7BHU|rcsb pdb:7BHV|rcsb pdb:7BHW|rcsb pdb:7BHX|rcsb pdb:7KCC|rcsb pdb:7KCE|rcsb pdb:7KCF|rcsb pdb:7KDA|rcsb pdb:7KDB|rcsb pdb:7L1A|reactome:R-HSA-156581|entrezgene/locuslink:4144(identity)	ensemblfungi:YDR502C(gene)|ensemblfungi:YDR502C_mRNA(transcript)|go:"GO:0006556"(S-adenosylmethionine biosynthetic process)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0046872"(metal ion binding)|interpro:IPR002133(S-adenosylmethionine synthetase)|interpro:IPR022628|interpro:IPR022629|interpro:IPR022630|interpro:IPR022631|interpro:IPR022636|reactome:R-SCE-156581|reactome:R-SCE-1614635|reactome:R-SCE-2408508|go:"GO:0004478"(methionine adenosyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006555"(methionine metabolic process)|sgd:S000002910|refseq:NP_010790.3|mint:P19358|dip:DIP-4001N|sgd:YDR502C(identity)	-	-	crc64:0AFCB0BA386F088B	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:8QDKkbuHcvQtfzy2XkVjCKjTK709606	rogid:fLg9TMOk+nR4ZuRNqkqur0qzv/E559292	intact-crc:7089C62D5B3C23ED|rigid:OAdSwEtKPQ2xBwonkNrjPt/ZKpY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UGJ1-2	uniprotkb:P18961	intact:EBI-10964469|ensembl:ENSP00000456648	intact:EBI-29484|uniprotkb:D6VZS6|ensemblfungi:YMR104C	psi-mi:q9ugj1-2(display_long)|uniprotkb:TUBGCP4(gene name)|psi-mi:TUBGCP4(display_short)|uniprotkb:76P(gene name synonym)|uniprotkb:GCP4(gene name synonym)|uniprotkb:Gamma-ring complex protein 76 kDa(gene name synonym)	psi-mi:ypk2_yeast(display_long)|uniprotkb:YPK2(gene name)|psi-mi:YPK2(display_short)|uniprotkb:YKR2(gene name synonym)|uniprotkb:YMR104C(locus name)|uniprotkb:YM9718.03C(orf name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11523683|imex:IM-24995-145	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-1052544(isoform-parent)|ensembl:ENSG00000137822(gene)|ensembl:ENST00000564079(transcript)|uniprotkb:Q9UGJ1-2(isoform-parent)|entrezgene/locuslink:27229(identity)	refseq:NP_013822.1|sgd:S000004710|dip:DIP-4438N|mint:P18961|ensemblfungi:YMR104C(gene)|ensemblfungi:YMR104C_mRNA(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0060237"(regulation of fungal-type cell wall organization)|go:"GO:0070941"(eisosome assembly)|go:"GO:0071555"(cell wall organization)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|sgd:YMR104C(identity)	-	-	crc64:E1FAB0295386A113	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:+lfeIRS3N2OU1+y84kUyKY7ePNA9606	rogid:wDHCJlSmOMy9MWExwxHzLA4+dO0559292	intact-crc:36AFAD713A7F9508|rigid:ipJEgY3MjfpnuYhhjgXoypki4dk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P18961	uniprotkb:Q8N5R6	intact:EBI-29484|uniprotkb:D6VZS6|ensemblfungi:YMR104C	intact:EBI-740841|intact:EBI-953781|uniprotkb:B3KQ49|uniprotkb:A8K3U4|uniprotkb:A8MPQ6|uniprotkb:A8MV61|uniprotkb:A8MVU9|uniprotkb:Q9H5Q6|uniprotkb:Q8TAX6|intact:EBI-2320546|intact:EBI-11522976	psi-mi:ypk2_yeast(display_long)|uniprotkb:YPK2(gene name)|psi-mi:YPK2(display_short)|uniprotkb:YKR2(gene name synonym)|uniprotkb:YMR104C(locus name)|uniprotkb:YM9718.03C(orf name)	psi-mi:ccd33_human(display_long)|uniprotkb:CCDC33(gene name)|psi-mi:CCDC33(display_short)|uniprotkb:Cancer/testis antigen 61(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11523656|imex:IM-24995-142	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013822.1|sgd:S000004710|dip:DIP-4438N|mint:P18961|ensemblfungi:YMR104C(gene)|ensemblfungi:YMR104C_mRNA(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0060237"(regulation of fungal-type cell wall organization)|go:"GO:0070941"(eisosome assembly)|go:"GO:0071555"(cell wall organization)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|sgd:YMR104C(identity)	refseq:NP_079331.3|interpro:IPR000008(C2 calcium-dependent membrane targeting)|go:"GO:0005777"(peroxisome)|refseq:NP_001274110.1|refseq:NP_877592.2|mint:Q8N5R6|interpro:IPR035892|interpro:IPR039889|entrezgene/locuslink:80125(identity)	-	crc64:E1FAB0295386A113	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2021/11/30	rogid:wDHCJlSmOMy9MWExwxHzLA4+dO0559292	rogid:eEIn7pQyfdHWx8TeLJpYy0i/gww9606	intact-crc:2EF30052F8947522|rigid:G9G1d64MxZogkpe+g+zrI4doMs4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O00444	uniprotkb:P18961	intact:EBI-746202|uniprotkb:Q8IYF0|uniprotkb:Q96Q95|uniprotkb:B2RAL0|uniprotkb:B7Z837|uniprotkb:B7Z8G7|uniprotkb:Q9UD84|uniprotkb:Q9UDE2|ensembl:ENSP00000270861	intact:EBI-29484|uniprotkb:D6VZS6|ensemblfungi:YMR104C	psi-mi:plk4_human(display_long)|uniprotkb:Polo-like kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase Sak(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 18(gene name synonym)|uniprotkb:PLK4(gene name)|psi-mi:PLK4(display_short)|uniprotkb:SAK(gene name synonym)|uniprotkb:STK18(gene name synonym)	psi-mi:ypk2_yeast(display_long)|uniprotkb:YPK2(gene name)|psi-mi:YPK2(display_short)|uniprotkb:YKR2(gene name synonym)|uniprotkb:YMR104C(locus name)|uniprotkb:YM9718.03C(orf name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11523665|imex:IM-24995-143	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001177728.1|refseq:NP_001177730.1|refseq:NP_055079.3|dip:DIP-34467N|rcsb pdb:5LHZ|rcsb pdb:6N45|rcsb pdb:6N46|rcsb pdb:6W38|rcsb pdb:6W3I|rcsb pdb:6W3J|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|rcsb pdb:5LHY|reactome:R-HSA-5620912|reactome:R-HSA-8854518|ensembl:ENSG00000142731(gene)|ensembl:ENST00000270861(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0001741"(XY body)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007099"(centriole replication)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0046601"(positive regulation of centriole replication)|go:"GO:0060271"(cilium assembly)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0098535"(de novo centriole assembly involved in multi-ciliated epithelial cell differentiation)|go:"GO:0098536"(deuterosome)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033696|interpro:IPR033698|interpro:IPR033699|interpro:IPR033700|mint:O00444|rcsb pdb:2N19|rcsb pdb:3COK|rcsb pdb:4JXF|rcsb pdb:4N7V|rcsb pdb:4N7Z|rcsb pdb:4N9J|rcsb pdb:4YUR|rcsb pdb:4YYP|entrezgene/locuslink:10733(identity)	refseq:NP_013822.1|sgd:S000004710|dip:DIP-4438N|mint:P18961|ensemblfungi:YMR104C(gene)|ensemblfungi:YMR104C_mRNA(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0060237"(regulation of fungal-type cell wall organization)|go:"GO:0070941"(eisosome assembly)|go:"GO:0071555"(cell wall organization)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|sgd:YMR104C(identity)	-	-	crc64:E1FAB0295386A113	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:xqjVEnoGXDk/+2AzLRAkyPK80OI9606	rogid:wDHCJlSmOMy9MWExwxHzLA4+dO0559292	intact-crc:01E6E7170926BBA0|rigid:t8IsHTPshCST0iHthikEDRrlCys	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9BRK4	uniprotkb:P18961	intact:EBI-741037|ensembl:ENSP00000359240|ensembl:ENSP00000359243|uniprotkb:Q8N3I0|uniprotkb:Q96J79|uniprotkb:Q96JL2|uniprotkb:B1AL14|uniprotkb:D3DR72	intact:EBI-29484|uniprotkb:D6VZS6|ensemblfungi:YMR104C	psi-mi:lzts2_human(display_long)|uniprotkb:Protein LAPSER1(gene name synonym)|uniprotkb:LZTS2(gene name)|psi-mi:LZTS2(display_short)|uniprotkb:KIAA1813(gene name synonym)|uniprotkb:LAPSER1(gene name synonym)	psi-mi:ypk2_yeast(display_long)|uniprotkb:YPK2(gene name)|psi-mi:YPK2(display_short)|uniprotkb:YKR2(gene name synonym)|uniprotkb:YMR104C(locus name)|uniprotkb:YM9718.03C(orf name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11523674|imex:IM-24995-144	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_115805.1|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030496"(midbody)|go:"GO:0031982"(vesicle)|go:"GO:0051013"(microtubule severing)|go:"GO:0051168"(nuclear export)|go:"GO:0051255"(spindle midzone assembly)|go:"GO:0060682"(primary ureteric bud growth)|go:"GO:0072197"(ureter morphogenesis)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|interpro:IPR028597|mint:Q9BRK4|ensembl:ENSG00000107816(gene)|ensembl:ENST00000370220(transcript)|ensembl:ENST00000370223(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0008285"(negative regulation of cell population proliferation)|refseq:XP_016872269.1|refseq:NP_001305028.1|refseq:NP_001305029.1|refseq:NP_001305030.1|refseq:XP_005270279.1|entrezgene/locuslink:84445(identity)	refseq:NP_013822.1|sgd:S000004710|dip:DIP-4438N|mint:P18961|ensemblfungi:YMR104C(gene)|ensemblfungi:YMR104C_mRNA(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0060237"(regulation of fungal-type cell wall organization)|go:"GO:0070941"(eisosome assembly)|go:"GO:0071555"(cell wall organization)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|sgd:YMR104C(identity)	-	-	crc64:E1FAB0295386A113	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:OaMJmnmfm6JniKUJeyg7fS6zRcw9606	rogid:wDHCJlSmOMy9MWExwxHzLA4+dO0559292	intact-crc:33ABF95E1F8E8984|rigid:jd2ap/wQphjhYJ/mLe0t8IsF0HU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P20053	uniprotkb:P14373	intact:EBI-219|uniprotkb:D6W4H8|ensemblfungi:YPR178W	intact:EBI-719493|uniprotkb:A2BE15|uniprotkb:Q5RJA8|uniprotkb:Q5ST26|uniprotkb:Q6LA73|uniprotkb:Q6NXR9|uniprotkb:Q9BZY6|uniprotkb:Q9UJL3|ensembl:ENSP00000383555|ensembl:ENSP00000392787|ensembl:ENSP00000405229|ensembl:ENSP00000414793|ensembl:ENSP00000366404	psi-mi:prp4_yeast(display_long)|uniprotkb:PRP4(gene name)|psi-mi:PRP4(display_short)|uniprotkb:RNA4(gene name synonym)|uniprotkb:YPR178W(locus name)|uniprotkb:P9705.6(orf name)|uniprotkb:Pre-mRNA-processing protein 4(gene name synonym)	psi-mi:tri27_human(display_long)|uniprotkb:TRIM27(gene name)|psi-mi:TRIM27(display_short)|uniprotkb:RNF76(gene name synonym)|uniprotkb:RFP(gene name synonym)|uniprotkb:Ret finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 27(gene name synonym)|uniprotkb:RING finger protein 76(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM27(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11523750|imex:IM-24995-152	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015504.1|sgd:S000006382|mint:P20053|dip:DIP-2607N|ensemblfungi:YPR178W(gene)|ensemblfungi:YPR178W_mRNA(transcript)|go:"GO:0000393"(spliceosomal conformational changes to generate catalytic conformation)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0030621"(U4 snRNA binding)|go:"GO:0034247"(snoRNA splicing)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR014906("Pre-mRNA processing factor 4 (PRP4) like")|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|rcsb pdb:3JCM|rcsb pdb:5GAN|rcsb pdb:5GAP|rcsb pdb:5NRL|rcsb pdb:5ZWM|rcsb pdb:5ZWO|sgd:YPR178W(identity)	refseq:NP_006501.1|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0090281"(negative regulation of calcium ion import)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR020457|interpro:IPR035791|interpro:IPR043136|mint:P14373|reactome:R-HSA-3232142|reactome:R-HSA-9635465|reactome:R-HSA-8948751|ensembl:ENSG00000204713(gene)|ensembl:ENSG00000215641(gene)|ensembl:ENSG00000229006(gene)|ensembl:ENSG00000234495(gene)|ensembl:ENSG00000237071(gene)|ensembl:ENST00000377199(transcript)|ensembl:ENST00000400720(transcript)|ensembl:ENST00000431123(transcript)|ensembl:ENST00000435528(transcript)|ensembl:ENST00000437160(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001650"(fibrillar center)|go:"GO:0002820"(negative regulation of adaptive immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|entrezgene/locuslink:5987(identity)	-	crc64:7CCCA3A92AC0CE78	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:vvz5G0rqqyrugTvAPelDKit9FpQ559292	rogid:dsfH5OUghD8KSaTz1SFw9OYVTK49606	intact-crc:CE1AF40ACE53CC78|rigid:POgDzDouQfkuac4iSySiCK+tyQ8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O43186	uniprotkb:P20053	intact:EBI-748171|uniprotkb:Q0QD45|ensembl:ENSP00000221996|ensembl:ENSP00000445565	intact:EBI-219|uniprotkb:D6W4H8|ensemblfungi:YPR178W	psi-mi:crx_human(display_long)|uniprotkb:CRX(gene name)|psi-mi:CRX(display_short)|uniprotkb:CORD2(gene name synonym)	psi-mi:prp4_yeast(display_long)|uniprotkb:PRP4(gene name)|psi-mi:PRP4(display_short)|uniprotkb:RNA4(gene name synonym)|uniprotkb:YPR178W(locus name)|uniprotkb:P9705.6(orf name)|uniprotkb:Pre-mRNA-processing protein 4(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11523741|imex:IM-24995-151	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000545.1|ensembl:ENSG00000105392(gene)|ensembl:ENST00000221996(transcript)|ensembl:ENST00000539067(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007601"(visual perception)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050896"(response to stimulus)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013851(Transcription factor Otx, C-terminal)|interpro:IPR017970|entrezgene/locuslink:1406(identity)	refseq:NP_015504.1|sgd:S000006382|mint:P20053|dip:DIP-2607N|ensemblfungi:YPR178W(gene)|ensemblfungi:YPR178W_mRNA(transcript)|go:"GO:0000393"(spliceosomal conformational changes to generate catalytic conformation)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0030621"(U4 snRNA binding)|go:"GO:0034247"(snoRNA splicing)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR014906("Pre-mRNA processing factor 4 (PRP4) like")|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|rcsb pdb:3JCM|rcsb pdb:5GAN|rcsb pdb:5GAP|rcsb pdb:5NRL|rcsb pdb:5ZWM|rcsb pdb:5ZWO|sgd:YPR178W(identity)	-	-	crc64:7CCCA3A92AC0CE78	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:v/bkO/0iLzq1Q2HtieWQQ40RF9M9606	rogid:vvz5G0rqqyrugTvAPelDKit9FpQ559292	intact-crc:211B5D4DD966FE87|rigid:5xdYT8xK3b48eAEKcfSQjFxSIxw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q13643	uniprotkb:P19955	intact:EBI-741101|ensembl:ENSP00000362107|uniprotkb:Q6I9T0|uniprotkb:Q9BVA2|uniprotkb:D3DPT6	intact:EBI-16295|ensemblfungi:YFR049W|uniprotkb:D6VTT2	psi-mi:fhl3_human(display_long)|uniprotkb:FHL3(gene name)|psi-mi:FHL3(display_short)|uniprotkb:SLIM2(gene name synonym)|uniprotkb:Skeletal muscle LIM-protein 2(gene name synonym)	psi-mi:rt31_yeast(display_long)|uniprotkb:YFR049W(locus name)|uniprotkb:YMR31(gene name)|psi-mi:YMR31(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11523701|imex:IM-24995-147	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004459.2|ensembl:ENSG00000183386(gene)|ensembl:ENST00000373016(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005925"(focal adhesion)|go:"GO:0007517"(muscle organ development)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0046872"(metal ion binding)|interpro:IPR001781(Zinc finger, LIM-type)|mint:Q13643|rcsb pdb:1WYH|rcsb pdb:2CUQ|rcsb pdb:2EHE|interpro:IPR037987|refseq:NP_001230807.1|dip:DIP-42030N|entrezgene/locuslink:2275(identity)	sgd:S000001945|ensemblfungi:YFR049W(gene)|ensemblfungi:YFR049W_mRNA(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005761"(mitochondrial ribosome)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006103"(2-oxoglutarate metabolic process)|interpro:IPR020373|go:"GO:0009353"(mitochondrial oxoglutarate dehydrogenase complex)|refseq:NP_116707.3|dip:DIP-5447N|mint:P19955|sgd:YFR049W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:RAo+b/VgFSnHSbgR+zXuxJvypxM9606	rogid:6QZyCc2+sOr3rdTswAxjMopU9/A559292	intact-crc:AFC50BA97C239368|rigid:5dxyVPMtLsP9iRozP88z/4JGD64	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8N5R6	uniprotkb:P20053	intact:EBI-740841|intact:EBI-953781|uniprotkb:B3KQ49|uniprotkb:A8K3U4|uniprotkb:A8MPQ6|uniprotkb:A8MV61|uniprotkb:A8MVU9|uniprotkb:Q9H5Q6|uniprotkb:Q8TAX6|intact:EBI-2320546|intact:EBI-11522976	intact:EBI-219|uniprotkb:D6W4H8|ensemblfungi:YPR178W	psi-mi:ccd33_human(display_long)|uniprotkb:CCDC33(gene name)|psi-mi:CCDC33(display_short)|uniprotkb:Cancer/testis antigen 61(gene name synonym)	psi-mi:prp4_yeast(display_long)|uniprotkb:PRP4(gene name)|psi-mi:PRP4(display_short)|uniprotkb:RNA4(gene name synonym)|uniprotkb:YPR178W(locus name)|uniprotkb:P9705.6(orf name)|uniprotkb:Pre-mRNA-processing protein 4(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11523719|imex:IM-24995-149	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_079331.3|interpro:IPR000008(C2 calcium-dependent membrane targeting)|go:"GO:0005777"(peroxisome)|refseq:NP_001274110.1|refseq:NP_877592.2|mint:Q8N5R6|interpro:IPR035892|interpro:IPR039889|entrezgene/locuslink:80125(identity)	refseq:NP_015504.1|sgd:S000006382|mint:P20053|dip:DIP-2607N|ensemblfungi:YPR178W(gene)|ensemblfungi:YPR178W_mRNA(transcript)|go:"GO:0000393"(spliceosomal conformational changes to generate catalytic conformation)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0030621"(U4 snRNA binding)|go:"GO:0034247"(snoRNA splicing)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR014906("Pre-mRNA processing factor 4 (PRP4) like")|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|rcsb pdb:3JCM|rcsb pdb:5GAN|rcsb pdb:5GAP|rcsb pdb:5NRL|rcsb pdb:5ZWM|rcsb pdb:5ZWO|sgd:YPR178W(identity)	-	-	crc64:7CCCA3A92AC0CE78	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2021/11/30	rogid:eEIn7pQyfdHWx8TeLJpYy0i/gww9606	rogid:vvz5G0rqqyrugTvAPelDKit9FpQ559292	intact-crc:1752DCE3D8A47BDA|rigid:ptA+Hsnjl/Y0xmHa4k1KOheQruE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O75928-2	uniprotkb:P20049	intact:EBI-348567|ensembl:ENSP00000317163|intact:EBI-7259183|intact:MINT-1455402	intact:EBI-19686|uniprotkb:D6VQG2|ensemblfungi:YBR166C	psi-mi:o75928-2(display_long)|uniprotkb:Msx-interacting zinc finger protein(gene name synonym)|uniprotkb:PIAS-NY protein(gene name synonym)|uniprotkb:Protein inhibitor of activated STAT x(gene name synonym)|uniprotkb:Protein inhibitor of activated STAT2(gene name synonym)|uniprotkb:PIAS2(gene name)|psi-mi:PIAS2(display_short)|uniprotkb:PIASX(gene name synonym)|uniprotkb:Androgen receptor-interacting protein 3(gene name synonym)|uniprotkb:DAB2-interacting protein(gene name synonym)|uniprotkb:PIASx-alpha(isoform synonym)|uniprotkb:ARIP3(isoform synonym)|uniprotkb:E3 SUMO-protein transferase PIAS2(gene name synonym)	psi-mi:tyr1_yeast(display_long)|uniprotkb:TYR1(gene name)|psi-mi:TYR1(display_short)|uniprotkb:YBR1218(orf name)|uniprotkb:YBR166C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11523710|imex:IM-24995-148	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-348555(pias2_human)|ensembl:ENSG00000078043(gene)|ensembl:ENST00000324794(transcript)|uniprotkb:O75928-2(isoform-parent)|entrezgene/locuslink:9063(identity)	refseq:NP_009725.1|sgd:S000000370|ensemblfungi:YBR166C(gene)|ensemblfungi:YBR166C_mRNA(transcript)|go:"GO:0004665"("prephenate dehydrogenase (NADP+) activity")|go:"GO:0005737"(cytoplasm)|go:"GO:0006570"(tyrosine metabolic process)|go:"GO:0006571"(tyrosine biosynthetic process)|go:"GO:0008652"(cellular amino acid biosynthetic process)|go:"GO:0008977"("prephenate dehydrogenase (NAD+) activity")|go:"GO:0070403"(NAD+ binding)|interpro:IPR003099(Prephenate dehydrogenase)|interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|interpro:IPR012385(Prephenate dehydrogenase, fungal)|interpro:IPR036291|dip:DIP-4627N|mint:P20049|sgd:YBR166C(identity)	-	isoform-comment:"Contains a glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) at position 562."	crc64:D483B93ABBC8F8F4	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:JNC3UGf8YuVcrXbFnO27d4orf4I9606	rogid:tqskEEcG2cewNJk/xHHqihVa8ss559292	intact-crc:C3EFF2F87FA00075|rigid:GzTNSfB4U5rOKiODhLM8nL6bcyY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:A0A024R0Y4	uniprotkb:P20053	intact:EBI-11523730|ensembl:ENSP00000477709|ensembl:ENSP00000478363|ensembl:ENSP00000481091	intact:EBI-219|uniprotkb:D6W4H8|ensemblfungi:YPR178W	psi-mi:a0a024r0y4_human(display_long)|uniprotkb:TADA2A(gene name)|psi-mi:TADA2A(display_short)|uniprotkb:TADA2L(gene name synonym)|uniprotkb:hCG_28187(orf name)	psi-mi:prp4_yeast(display_long)|uniprotkb:PRP4(gene name)|psi-mi:PRP4(display_short)|uniprotkb:RNA4(gene name synonym)|uniprotkb:YPR178W(locus name)|uniprotkb:P9705.6(orf name)|uniprotkb:Pre-mRNA-processing protein 4(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11523728|imex:IM-24995-150	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001159577.2|refseq:NP_001479.4|ensembl:ENSG00000276234(gene)|ensembl:ENST00000612272(transcript)|ensembl:ENST00000615182(transcript)|ensembl:ENST00000620628(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031063"(regulation of histone deacetylation)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0035065"(regulation of histone acetylation)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090043"(regulation of tubulin deacetylation)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016827(Transcriptional adaptor 2)|interpro:IPR017884|interpro:IPR017930|interpro:IPR036388|interpro:IPR041983|interpro:IPR043145|entrezgene/locuslink:6871(identity)	refseq:NP_015504.1|sgd:S000006382|mint:P20053|dip:DIP-2607N|ensemblfungi:YPR178W(gene)|ensemblfungi:YPR178W_mRNA(transcript)|go:"GO:0000393"(spliceosomal conformational changes to generate catalytic conformation)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0030621"(U4 snRNA binding)|go:"GO:0034247"(snoRNA splicing)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR014906("Pre-mRNA processing factor 4 (PRP4) like")|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|rcsb pdb:3JCM|rcsb pdb:5GAN|rcsb pdb:5GAP|rcsb pdb:5NRL|rcsb pdb:5ZWM|rcsb pdb:5ZWO|sgd:YPR178W(identity)	-	-	crc64:7CCCA3A92AC0CE78	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:IGh7vC68gMLe+tAVGM4gc0rzc6Y9606	rogid:vvz5G0rqqyrugTvAPelDKit9FpQ559292	intact-crc:71038E9968C315DD|rigid:OC6yQLt062fWuC2VxG3k80O5t54	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P20081	uniprotkb:P81877	intact:EBI-6961|uniprotkb:D6W147|ensemblfungi:YNL135C	intact:EBI-748077|uniprotkb:Q8N2Q2|uniprotkb:Q9BWW6|uniprotkb:Q9Y4T7|uniprotkb:B7Z2L9|uniprotkb:E9PDA8|uniprotkb:B2R5W1|uniprotkb:B7Z1J2|uniprotkb:B7Z665|uniprotkb:D6RH18|uniprotkb:E9PB74|intact:EBI-28967061|ensembl:ENSP00000322977	psi-mi:fkbp_yeast(display_long)|uniprotkb:RBP1(gene name synonym)|uniprotkb:N1213(orf name)|uniprotkb:N1845(orf name)|uniprotkb:YNL135C(locus name)|uniprotkb:FPR1(gene name)|psi-mi:FPR1(display_short)|uniprotkb:FKB1(gene name synonym)|uniprotkb:Peptidyl-prolyl cis-trans isomerase(gene name synonym)|uniprotkb:Rapamycin-binding protein(gene name synonym)	psi-mi:ssbp2_human(display_long)|uniprotkb:Sequence-specific single-stranded-DNA-binding protein 2(gene name synonym)|uniprotkb:SSBP2(gene name)|psi-mi:SSBP2(display_short)|uniprotkb:SSDP2(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11523821|imex:IM-24995-159	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014264.1|sgd:S000005079|dip:DIP-1263N|mint:P20081|ensemblfungi:YNL135C(gene)|ensemblfungi:YNL135C_mRNA(transcript)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005527"(macrolide binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006325"(chromatin organization)|go:"GO:0006457"(protein folding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:1901710"(regulation of homoserine biosynthetic process)|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)|rcsb pdb:1YAT|sgd:YNL135C(identity)	ensembl:ENSP00000322977|ensembl:ENST00000505980|ensembl:ENSP00000423969|ensembl:ENST00000509053|ensembl:ENSP00000422961|ensembl:ENST00000514493|ensembl:ENSP00000426183|ensembl:ENST00000515395|ensembl:ENSP00000424657|refseq:NP_001243661.1|refseq:NP_036578.2|refseq:NP_001243665.1|refseq:NP_001243663.1|refseq:NP_001243664.1|refseq:NP_001243662.1|ensembl:ENSG00000145687(gene)|ensembl:ENST00000320672(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR008116(Sequence-specific single-strand DNA-binding protein)|mint:P81877|rcsb pdb:6IWV|rcsb pdb:6TYD|dip:DIP-29459N|entrezgene/locuslink:23635(identity)	-	crc64:65C134830D300C06	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:8afvGSk+mPghtqkVoWd2rHJXXhQ559292	rogid:CMmZPTurp1G6Y2q7GP/pTMlFM549606	intact-crc:3157B2C849140F8A|rigid:uZJRlMh9x8XnKjRL2xHC18tthvk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P20081	uniprotkb:P53992	intact:EBI-6961|uniprotkb:D6W147|ensemblfungi:YNL135C	intact:EBI-81134|uniprotkb:Q8WV25|ensembl:ENSP00000321845|ensembl:ENSP00000343405|uniprotkb:B4DZT4	psi-mi:fkbp_yeast(display_long)|uniprotkb:RBP1(gene name synonym)|uniprotkb:N1213(orf name)|uniprotkb:N1845(orf name)|uniprotkb:YNL135C(locus name)|uniprotkb:FPR1(gene name)|psi-mi:FPR1(display_short)|uniprotkb:FKB1(gene name synonym)|uniprotkb:Peptidyl-prolyl cis-trans isomerase(gene name synonym)|uniprotkb:Rapamycin-binding protein(gene name synonym)	psi-mi:sc24c_human(display_long)|uniprotkb:SEC24C(gene name)|psi-mi:SEC24C(display_short)|uniprotkb:KIAA0079(gene name synonym)|uniprotkb:SEC24-related protein C(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11523812|imex:IM-24995-158	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014264.1|sgd:S000005079|dip:DIP-1263N|mint:P20081|ensemblfungi:YNL135C(gene)|ensemblfungi:YNL135C_mRNA(transcript)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005527"(macrolide binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006325"(chromatin organization)|go:"GO:0006457"(protein folding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:1901710"(regulation of homoserine biosynthetic process)|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)|rcsb pdb:1YAT|sgd:YNL135C(identity)	go:"GO:0090110"(COPII-coated vesicle cargo loading)|go:"GO:0070971"(endoplasmic reticulum exit site)|interpro:IPR006895(Zinc finger, Sec23/Sec24-type)|interpro:IPR006896(Sec23/Sec24 trunk region)|interpro:IPR006900(Sec23/Sec24 helical region)|interpro:IPR007123(Gelsolin region)|interpro:IPR012990(Sec23/Sec24 beta-sandwich)|interpro:IPR029006|interpro:IPR036174|interpro:IPR036175|interpro:IPR036180|interpro:IPR036465|interpro:IPR041742|mint:P53992|rcsb pdb:3EH2|rcsb pdb:6PU1|reactome:R-HSA-1655829|reactome:R-HSA-204005|reactome:R-HSA-2132295|reactome:R-HSA-983170|reactome:R-HSA-5694530|ensembl:ENSG00000176986(gene)|ensembl:ENST00000339365(transcript)|ensembl:ENST00000345254(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0008270"(zinc ion binding)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0030127"(COPII vesicle coat)|refseq:NP_004913.2|refseq:NP_940999.1|dip:DIP-30981N|entrezgene/locuslink:9632(identity)	-	crc64:65C134830D300C06	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:8afvGSk+mPghtqkVoWd2rHJXXhQ559292	rogid:kOKJkIWFOlIpRFLj5JshAGqAg6s9606	intact-crc:B6BDDE25F1D8C35D|rigid:Zf31zF/KLpq8P12LqD+1kWSQAIY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P20081	uniprotkb:A0A0C4DGF1	intact:EBI-6961|uniprotkb:D6W147|ensemblfungi:YNL135C	intact:EBI-10188476|ensembl:ENSP00000433657	psi-mi:fkbp_yeast(display_long)|uniprotkb:RBP1(gene name synonym)|uniprotkb:N1213(orf name)|uniprotkb:N1845(orf name)|uniprotkb:YNL135C(locus name)|uniprotkb:FPR1(gene name)|psi-mi:FPR1(display_short)|uniprotkb:FKB1(gene name synonym)|uniprotkb:Peptidyl-prolyl cis-trans isomerase(gene name synonym)|uniprotkb:Rapamycin-binding protein(gene name synonym)	psi-mi:a0a0c4dgf1_human(display_long)|uniprotkb:ZBTB32(gene name)|psi-mi:ZBTB32(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11523803|imex:IM-24995-157	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014264.1|sgd:S000005079|dip:DIP-1263N|mint:P20081|ensemblfungi:YNL135C(gene)|ensemblfungi:YNL135C_mRNA(transcript)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005527"(macrolide binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006325"(chromatin organization)|go:"GO:0006457"(protein folding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:1901710"(regulation of homoserine biosynthetic process)|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)|rcsb pdb:1YAT|sgd:YNL135C(identity)	interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|ensembl:ENSG00000011590(gene)|ensembl:ENST00000481182(transcript)|go:"GO:0042802"(identical protein binding)|entrezgene/locuslink:27033(identity)	-	crc64:65C134830D300C06	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:8afvGSk+mPghtqkVoWd2rHJXXhQ559292	rogid:w3k7YT4kw/T+Xi5YBqGHSpHtwMM9606	intact-crc:FA19DF84E232A4E8|rigid:aH70cUocyuJplPpMqCt6QIeja2w	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8N684-3	uniprotkb:P20053	intact:EBI-11523759|ensembl:ENSP00000345412	intact:EBI-219|uniprotkb:D6W4H8|ensemblfungi:YPR178W	psi-mi:q8n684-3(display_long)|uniprotkb:Cleavage factor Im complex 59 kDa subunit(gene name synonym)|uniprotkb:CPSF7(gene name)|psi-mi:CPSF7(display_short)|uniprotkb:Cleavage and polyadenylation specificity factor 59 kDa subunit(gene name synonym)|uniprotkb:Pre-mRNA cleavage factor Im 59 kDa subunit(gene name synonym)	psi-mi:prp4_yeast(display_long)|uniprotkb:PRP4(gene name)|psi-mi:PRP4(display_short)|uniprotkb:RNA4(gene name synonym)|uniprotkb:YPR178W(locus name)|uniprotkb:P9705.6(orf name)|uniprotkb:Pre-mRNA-processing protein 4(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11523763|imex:IM-24995-153	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-746909(isoform-parent)|ensembl:ENSG00000149532(gene)|ensembl:ENST00000340437(transcript)|uniprotkb:Q8N684-3(isoform-parent)|entrezgene/locuslink:79869(identity)	refseq:NP_015504.1|sgd:S000006382|mint:P20053|dip:DIP-2607N|ensemblfungi:YPR178W(gene)|ensemblfungi:YPR178W_mRNA(transcript)|go:"GO:0000393"(spliceosomal conformational changes to generate catalytic conformation)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0030621"(U4 snRNA binding)|go:"GO:0034247"(snoRNA splicing)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR014906("Pre-mRNA processing factor 4 (PRP4) like")|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|rcsb pdb:3JCM|rcsb pdb:5GAN|rcsb pdb:5GAP|rcsb pdb:5NRL|rcsb pdb:5ZWM|rcsb pdb:5ZWO|sgd:YPR178W(identity)	-	-	crc64:7CCCA3A92AC0CE78	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:hnk6o9HBKsdIRWKRuEdjdByVKxM9606	rogid:vvz5G0rqqyrugTvAPelDKit9FpQ559292	intact-crc:DFDD938CF1DB2CC7|rigid:5QtYmVwYNwdsIJirXMxzEGeQUeU	false	sufficient binding region:44-514	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8NHQ1	uniprotkb:P20053	intact:EBI-739624|ensembl:ENSP00000264982|ensembl:ENSP00000419231|uniprotkb:Q96B31|uniprotkb:Q9H2C3|uniprotkb:Q9H2Z1|uniprotkb:Q9H940|uniprotkb:D3DNE9|uniprotkb:B7Z5I8|uniprotkb:B7Z7E8|uniprotkb:F5GZX8	intact:EBI-219|uniprotkb:D6W4H8|ensemblfungi:YPR178W	psi-mi:cep70_human(display_long)|uniprotkb:CEP70(gene name)|psi-mi:CEP70(display_short)|uniprotkb:BITE(gene name synonym)|uniprotkb:p10-binding protein(gene name synonym)	psi-mi:prp4_yeast(display_long)|uniprotkb:PRP4(gene name)|psi-mi:PRP4(display_short)|uniprotkb:RNA4(gene name synonym)|uniprotkb:YPR178W(locus name)|uniprotkb:P9705.6(orf name)|uniprotkb:Pre-mRNA-processing protein 4(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11523783|imex:IM-24995-155	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114107(gene)|ensembl:ENST00000264982(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|interpro:IPR019734|interpro:IPR037692|mint:Q8NHQ1|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|ensembl:ENST00000484888(transcript)|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_077817.2|refseq:XP_016862764.1|refseq:NP_001275893.1|refseq:NP_001275894.1|refseq:NP_001275895.1|refseq:NP_001275896.1|refseq:NP_001307527.1|refseq:NP_001307529.1|entrezgene/locuslink:80321(identity)	refseq:NP_015504.1|sgd:S000006382|mint:P20053|dip:DIP-2607N|ensemblfungi:YPR178W(gene)|ensemblfungi:YPR178W_mRNA(transcript)|go:"GO:0000393"(spliceosomal conformational changes to generate catalytic conformation)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0030621"(U4 snRNA binding)|go:"GO:0034247"(snoRNA splicing)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR014906("Pre-mRNA processing factor 4 (PRP4) like")|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|rcsb pdb:3JCM|rcsb pdb:5GAN|rcsb pdb:5GAP|rcsb pdb:5NRL|rcsb pdb:5ZWM|rcsb pdb:5ZWO|sgd:YPR178W(identity)	-	-	crc64:7CCCA3A92AC0CE78	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:S4yveQWcvdVtAUX65gqrJ5Dv0Mc9606	rogid:vvz5G0rqqyrugTvAPelDKit9FpQ559292	intact-crc:3B1ABEDCC76C3B85|rigid:bYutni7rDWOdZwLAyW9uUowQ90M	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P20053	uniprotkb:Q8N6Y0	intact:EBI-219|uniprotkb:D6W4H8|ensemblfungi:YPR178W	intact:EBI-739895|uniprotkb:Q8NBX7|uniprotkb:Q96KH3|uniprotkb:Q9BYI8|uniprotkb:A8K7L6|uniprotkb:B2RCR9|ensembl:ENSP00000252597	psi-mi:prp4_yeast(display_long)|uniprotkb:PRP4(gene name)|psi-mi:PRP4(display_short)|uniprotkb:RNA4(gene name synonym)|uniprotkb:YPR178W(locus name)|uniprotkb:P9705.6(orf name)|uniprotkb:Pre-mRNA-processing protein 4(gene name synonym)	psi-mi:usbp1_human(display_long)|uniprotkb:USHBP1(gene name)|psi-mi:USHBP1(display_short)|uniprotkb:MCC-2(gene name synonym)|uniprotkb:AIE-75-binding protein(gene name synonym)|uniprotkb:AIEBP(gene name synonym)|uniprotkb:MCC2(gene name synonym)|uniprotkb:Mutated in colon cancer protein 2(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11523774|imex:IM-24995-154	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015504.1|sgd:S000006382|mint:P20053|dip:DIP-2607N|ensemblfungi:YPR178W(gene)|ensemblfungi:YPR178W_mRNA(transcript)|go:"GO:0000393"(spliceosomal conformational changes to generate catalytic conformation)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0030621"(U4 snRNA binding)|go:"GO:0034247"(snoRNA splicing)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR014906("Pre-mRNA processing factor 4 (PRP4) like")|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|rcsb pdb:3JCM|rcsb pdb:5GAN|rcsb pdb:5GAP|rcsb pdb:5NRL|rcsb pdb:5ZWM|rcsb pdb:5ZWO|sgd:YPR178W(identity)	refseq:NP_001284632.1|refseq:NP_114147.2|refseq:NP_001308346.1|ensembl:ENSG00000130307(gene)|ensembl:ENST00000252597(transcript)|go:"GO:0030165"(PDZ domain binding)|interpro:IPR019536|interpro:IPR040171|entrezgene/locuslink:83878(identity)	-	crc64:7CCCA3A92AC0CE78	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:vvz5G0rqqyrugTvAPelDKit9FpQ559292	rogid:vY1qx73Ju/z7WDu6k1kd10ZDVRo9606	intact-crc:C07C1F8E5F72F43A|rigid:oGHx2Y1m3J2Qzbyujb+NjaM4buI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P20053	uniprotkb:Q9UJV3-2	intact:EBI-219|uniprotkb:D6W4H8|ensemblfungi:YPR178W	intact:EBI-10172526|ensembl:ENSP00000413976	psi-mi:prp4_yeast(display_long)|uniprotkb:PRP4(gene name)|psi-mi:PRP4(display_short)|uniprotkb:RNA4(gene name synonym)|uniprotkb:YPR178W(locus name)|uniprotkb:P9705.6(orf name)|uniprotkb:Pre-mRNA-processing protein 4(gene name synonym)	psi-mi:q9ujv3-2(display_long)|uniprotkb:RING-type E3 ubiquitin transferase MID2(gene name synonym)|uniprotkb:FXY2(gene name synonym)|uniprotkb:Midin-2(gene name synonym)|uniprotkb:Midline defect 2(gene name synonym)|uniprotkb:Midline-2(gene name synonym)|uniprotkb:RING finger protein 60(gene name synonym)|uniprotkb:RNF60(gene name synonym)|uniprotkb:TRIM1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 1(gene name synonym)|uniprotkb:MID2(gene name)|psi-mi:MID2(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11523792|imex:IM-24995-156	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015504.1|sgd:S000006382|mint:P20053|dip:DIP-2607N|ensemblfungi:YPR178W(gene)|ensemblfungi:YPR178W_mRNA(transcript)|go:"GO:0000393"(spliceosomal conformational changes to generate catalytic conformation)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0030621"(U4 snRNA binding)|go:"GO:0034247"(snoRNA splicing)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR014906("Pre-mRNA processing factor 4 (PRP4) like")|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|rcsb pdb:3JCM|rcsb pdb:5GAN|rcsb pdb:5GAP|rcsb pdb:5NRL|rcsb pdb:5ZWM|rcsb pdb:5ZWO|sgd:YPR178W(identity)	intact:EBI-751983(isoform-parent)|uniprotkb:Q9UJV3-2(isoform-parent)|ensembl:ENSG00000080561(gene)|ensembl:ENST00000443968(transcript)|entrezgene/locuslink:11043(identity)	-	crc64:7CCCA3A92AC0CE78	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:vvz5G0rqqyrugTvAPelDKit9FpQ559292	rogid:/FJ+V2H7SaWon7caUWkEkmHFVxQ9606	intact-crc:EE8F191422EEE031|rigid:Y29ymQkU+f+NbtmdHZNAvPot/9U	false	-	sufficient binding region:21-705	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P20081	uniprotkb:Q8N684-3	intact:EBI-6961|uniprotkb:D6W147|ensemblfungi:YNL135C	intact:EBI-11523759|ensembl:ENSP00000345412	psi-mi:fkbp_yeast(display_long)|uniprotkb:RBP1(gene name synonym)|uniprotkb:N1213(orf name)|uniprotkb:N1845(orf name)|uniprotkb:YNL135C(locus name)|uniprotkb:FPR1(gene name)|psi-mi:FPR1(display_short)|uniprotkb:FKB1(gene name synonym)|uniprotkb:Peptidyl-prolyl cis-trans isomerase(gene name synonym)|uniprotkb:Rapamycin-binding protein(gene name synonym)	psi-mi:q8n684-3(display_long)|uniprotkb:Cleavage factor Im complex 59 kDa subunit(gene name synonym)|uniprotkb:CPSF7(gene name)|psi-mi:CPSF7(display_short)|uniprotkb:Cleavage and polyadenylation specificity factor 59 kDa subunit(gene name synonym)|uniprotkb:Pre-mRNA cleavage factor Im 59 kDa subunit(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11523861|imex:IM-24995-163	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014264.1|sgd:S000005079|dip:DIP-1263N|mint:P20081|ensemblfungi:YNL135C(gene)|ensemblfungi:YNL135C_mRNA(transcript)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005527"(macrolide binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006325"(chromatin organization)|go:"GO:0006457"(protein folding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:1901710"(regulation of homoserine biosynthetic process)|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)|rcsb pdb:1YAT|sgd:YNL135C(identity)	intact:EBI-746909(isoform-parent)|ensembl:ENSG00000149532(gene)|ensembl:ENST00000340437(transcript)|uniprotkb:Q8N684-3(isoform-parent)|entrezgene/locuslink:79869(identity)	-	crc64:65C134830D300C06	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:8afvGSk+mPghtqkVoWd2rHJXXhQ559292	rogid:hnk6o9HBKsdIRWKRuEdjdByVKxM9606	intact-crc:9BB96AD6DE0417D7|rigid:eeeSKW6VR6Te456svsfGznIKuDY	false	-	sufficient binding region:44-514	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P20081	uniprotkb:Q15427	intact:EBI-6961|uniprotkb:D6W147|ensemblfungi:YNL135C	intact:EBI-348469|ensembl:ENSP00000271628|intact:EBI-1047735|uniprotkb:Q5SZ63	psi-mi:fkbp_yeast(display_long)|uniprotkb:RBP1(gene name synonym)|uniprotkb:N1213(orf name)|uniprotkb:N1845(orf name)|uniprotkb:YNL135C(locus name)|uniprotkb:FPR1(gene name)|psi-mi:FPR1(display_short)|uniprotkb:FKB1(gene name synonym)|uniprotkb:Peptidyl-prolyl cis-trans isomerase(gene name synonym)|uniprotkb:Rapamycin-binding protein(gene name synonym)	psi-mi:sf3b4_human(display_long)|uniprotkb:SF3B4(gene name)|psi-mi:SF3B4(display_short)|uniprotkb:SAP49(gene name synonym)|uniprotkb:Spliceosome-associated protein 49(gene name synonym)|uniprotkb:Pre-mRNA-splicing factor SF3b 49 kDa subunit(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11523830|imex:IM-24995-160	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014264.1|sgd:S000005079|dip:DIP-1263N|mint:P20081|ensemblfungi:YNL135C(gene)|ensemblfungi:YNL135C_mRNA(transcript)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005527"(macrolide binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006325"(chromatin organization)|go:"GO:0006457"(protein folding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:1901710"(regulation of homoserine biosynthetic process)|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)|rcsb pdb:1YAT|sgd:YNL135C(identity)	refseq:NP_005841.1|ensembl:ENSG00000143368(gene)|ensembl:ENST00000271628(transcript)|rcsb pdb:6QX9|rcsb pdb:6Y53|rcsb pdb:6Y5Q|rcsb pdb:7ABG|rcsb pdb:7ABH|rcsb pdb:7ABI|rcsb pdb:7DVQ|reactome:R-HSA-72163|reactome:R-HSA-72165|rcsb pdb:6AHD|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:1990935"(splicing factor binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034158|go:"GO:0000375"(RNA splicing, via transesterification reactions)|interpro:IPR034159|interpro:IPR035979|mint:Q15427|rcsb pdb:1X5T|rcsb pdb:5GVQ|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|entrezgene/locuslink:10262(identity)	-	crc64:65C134830D300C06	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:8afvGSk+mPghtqkVoWd2rHJXXhQ559292	rogid:Jgy6WmBFKkphpZLLte2GgsagUVI9606	intact-crc:06D3082EDC5FB97A|rigid:225teJT55udQNVL3ZYsd/JkGmp0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P20081	uniprotkb:Q16630-2	intact:EBI-6961|uniprotkb:D6W147|ensemblfungi:YNL135C	intact:EBI-11088043|ensembl:ENSP00000266679	psi-mi:fkbp_yeast(display_long)|uniprotkb:RBP1(gene name synonym)|uniprotkb:N1213(orf name)|uniprotkb:N1845(orf name)|uniprotkb:YNL135C(locus name)|uniprotkb:FPR1(gene name)|psi-mi:FPR1(display_short)|uniprotkb:FKB1(gene name synonym)|uniprotkb:Peptidyl-prolyl cis-trans isomerase(gene name synonym)|uniprotkb:Rapamycin-binding protein(gene name synonym)	psi-mi:q16630-2(display_long)|uniprotkb:CPSF6(gene name)|psi-mi:CPSF6(display_short)|uniprotkb:CFIM68(gene name synonym)|uniprotkb:Cleavage and polyadenylation specificity factor 68 kDa subunit(gene name synonym)|uniprotkb:Pre-mRNA cleavage factor Im 68 kDa subunit(gene name synonym)|uniprotkb:Protein HPBRII-4/7(gene name synonym)|uniprotkb:Cleavage factor Im complex 68 kDa subunit(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11523839|imex:IM-24995-161	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014264.1|sgd:S000005079|dip:DIP-1263N|mint:P20081|ensemblfungi:YNL135C(gene)|ensemblfungi:YNL135C_mRNA(transcript)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005527"(macrolide binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006325"(chromatin organization)|go:"GO:0006457"(protein folding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:1901710"(regulation of homoserine biosynthetic process)|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)|rcsb pdb:1YAT|sgd:YNL135C(identity)	intact:EBI-358410(isoform-parent)|ensembl:ENSG00000111605(gene)|ensembl:ENST00000266679(transcript)|uniprotkb:Q16630-2(isoform-parent)|entrezgene/locuslink:11052(identity)	-	crc64:65C134830D300C06	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:8afvGSk+mPghtqkVoWd2rHJXXhQ559292	rogid:y66l9ctsSYs6fhxdYD5CJ0cDZFA9606	intact-crc:2C267B98EA708FA1|rigid:tJHZJQq9S7vVqWv1C+ntEmixQd8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q16630-3	uniprotkb:P20081	intact:EBI-11523850	intact:EBI-6961|uniprotkb:D6W147|ensemblfungi:YNL135C	psi-mi:q16630-3(display_long)|uniprotkb:CFIM68(gene name synonym)|uniprotkb:Cleavage and polyadenylation specificity factor 68 kDa subunit(gene name synonym)|uniprotkb:Pre-mRNA cleavage factor Im 68 kDa subunit(gene name synonym)|uniprotkb:Protein HPBRII-4/7(gene name synonym)|uniprotkb:CPSF6(gene name)|psi-mi:CPSF6(display_short)|uniprotkb:Cleavage factor Im complex 68 kDa subunit(gene name synonym)	psi-mi:fkbp_yeast(display_long)|uniprotkb:RBP1(gene name synonym)|uniprotkb:N1213(orf name)|uniprotkb:N1845(orf name)|uniprotkb:YNL135C(locus name)|uniprotkb:FPR1(gene name)|psi-mi:FPR1(display_short)|uniprotkb:FKB1(gene name synonym)|uniprotkb:Peptidyl-prolyl cis-trans isomerase(gene name synonym)|uniprotkb:Rapamycin-binding protein(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11523848|imex:IM-24995-162	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-358410(isoform-parent)|entrezgene/locuslink:11052(identity)	refseq:NP_014264.1|sgd:S000005079|dip:DIP-1263N|mint:P20081|ensemblfungi:YNL135C(gene)|ensemblfungi:YNL135C_mRNA(transcript)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005527"(macrolide binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006325"(chromatin organization)|go:"GO:0006457"(protein folding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:1901710"(regulation of homoserine biosynthetic process)|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)|rcsb pdb:1YAT|sgd:YNL135C(identity)	-	-	crc64:65C134830D300C06	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:diwzHQNNZ4fMHYzs292gLpdKfE09606	rogid:8afvGSk+mPghtqkVoWd2rHJXXhQ559292	intact-crc:A47788452122E807|rigid:MYZyptYN7WodpKxm8QFAfiQIfvE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96IK5	uniprotkb:P20459	intact:EBI-2548508|ensembl:ENSP00000282570|uniprotkb:Q9H826|uniprotkb:Q9H8V7|uniprotkb:Q9H927	intact:EBI-8915|uniprotkb:E9P8T6|ensemblfungi:YJR007W|uniprotkb:D6VWI2	psi-mi:gmcl1_human(display_long)|uniprotkb:GMCL1(gene name)|psi-mi:GMCL1(display_short)|uniprotkb:GCL(gene name synonym)|uniprotkb:BTBD13(gene name synonym)|uniprotkb:SPATA29(gene name synonym)|uniprotkb:Spermatogenesis-associated protein 29(gene name synonym)	psi-mi:if2a_yeast(display_long)|uniprotkb:SUI2(gene name)|psi-mi:SUI2(display_short)|uniprotkb:TIF211(gene name synonym)|uniprotkb:YJR007W(locus name)|uniprotkb:J1429(orf name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11523921|imex:IM-24995-169	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000087338(gene)|ensembl:ENST00000282570(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0007281"(germ cell development)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016363"(nuclear matrix)|go:"GO:0042802"(identical protein binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR043380|refseq:NP_848526.1|entrezgene/locuslink:64395(identity)	interpro:IPR022967|interpro:IPR024054|interpro:IPR024055|interpro:IPR044126|rcsb pdb:1Q46|rcsb pdb:2A19|rcsb pdb:2A1A|rcsb pdb:3J81|rcsb pdb:3JAP|rcsb pdb:3JAQ|rcsb pdb:6FYX|rcsb pdb:6FYY|rcsb pdb:6GSM|rcsb pdb:6GSN|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6JLY|rcsb pdb:6JLZ|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-156827|reactome:R-SCE-381042|reactome:R-SCE-72649|reactome:R-SCE-72695|reactome:R-SCE-72702|reactome:R-SCE-72731|ensemblfungi:YJR007W(gene)|ensemblfungi:YJR007W_mRNA(transcript)|go:"GO:0001731"(formation of translation preinitiation complex)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005850"(eukaryotic translation initiation factor 2 complex)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0043022"(ribosome binding)|go:"GO:0043614"(multi-eIF complex)|interpro:IPR003029(S1, RNA binding)|interpro:IPR011488(Eukaryotic translation initiation factor 2, alpha subunit)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|refseq:NP_012540.3|sgd:S000003767|mint:P20459|dip:DIP-2327N|sgd:YJR007W(identity)	-	-	crc64:AF4F1C80303A4E98	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:ED8yqySVu7BWxpw3DUSNBZSQWrk9606	rogid:9/iGImP9/c8HSYwgmItME27z7lE559292	intact-crc:C837FB0D75166022|rigid:IoMb+WSQ/W6Elnkz1GDET4tvspo	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P20133	uniprotkb:Q9UJC3	intact:EBI-3559|uniprotkb:P32433|uniprotkb:D6W4H7|ensemblfungi:YPR176C	intact:EBI-746704|uniprotkb:O60561|uniprotkb:Q5TG44|uniprotkb:A8MU44|uniprotkb:B4DX15|uniprotkb:A8K8E9|intact:EBI-10969618|ensembl:ENSP00000360252	psi-mi:pgtb2_yeast(display_long)|uniprotkb:Geranylgeranyl transferase type II subunit beta(gene name synonym)|uniprotkb:Type II protein geranyl-geranyltransferase subunit beta(gene name synonym)|uniprotkb:YPT1/SEC4 proteins geranylgeranyltransferase subunit beta(gene name synonym)|uniprotkb:BET2(gene name)|psi-mi:BET2(display_short)|uniprotkb:YPR176C(locus name)|uniprotkb:P9705.12(orf name)	psi-mi:hook1_human(display_long)|uniprotkb:HOOK1(gene name)|psi-mi:HOOK1(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11523912|imex:IM-24995-168	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015502.1|sgd:S000006380|reactome:R-SCE-6803205|reactome:R-SCE-8873719|dip:DIP-2214N|ensemblfungi:YPR176C(gene)|ensemblfungi:YPR176C_mRNA(transcript)|go:"GO:0004663"(Rab geranylgeranyltransferase activity)|go:"GO:0005829"(cytosol)|go:"GO:0005968"(Rab-protein geranylgeranyltransferase complex)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0008270"(zinc ion binding)|go:"GO:0018342"(protein prenylation)|go:"GO:0018344"(protein geranylgeranylation)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001330(Prenyltransferase/squalene oxidase)|interpro:IPR008930(Terpenoid cylases/protein prenyltransferase alpha-alpha toroid)|interpro:IPR026873|sgd:YPR176C(identity)	refseq:NP_056972.1|ensembl:ENSG00000134709(gene)|ensembl:ENST00000371208(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0007030"(Golgi organization)|go:"GO:0007032"(endosome organization)|go:"GO:0007040"(lysosome organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0015031"(protein transport)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0051959"(dynein light intermediate chain binding)|go:"GO:0070695"(FHF complex)|go:"GO:1905198"(manchette assembly)|go:"GO:1905719"(protein localization to perinuclear region of cytoplasm)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR008636(HOOK)|interpro:IPR036872|interpro:IPR043936|mint:Q9UJC3|entrezgene/locuslink:51361(identity)	-	crc64:6A9C44DFBE62AAFC	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Fxribu0N2yK6IA2GZDfO0YmqLAo559292	rogid:QOcYbuKfnNIlNKzos5v+0+A2h3I9606	intact-crc:BBD5B382490EF6FE|rigid:FQ1SnE45bUOCAXYw9TLiJyl8nCw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P20133	uniprotkb:Q15008	intact:EBI-3559|uniprotkb:P32433|uniprotkb:D6W4H7|ensemblfungi:YPR176C	intact:EBI-359701|uniprotkb:E9PHI9|uniprotkb:A8K2E0|ensembl:ENSP00000295901|uniprotkb:Q6UV22	psi-mi:pgtb2_yeast(display_long)|uniprotkb:Geranylgeranyl transferase type II subunit beta(gene name synonym)|uniprotkb:Type II protein geranyl-geranyltransferase subunit beta(gene name synonym)|uniprotkb:YPT1/SEC4 proteins geranylgeranyltransferase subunit beta(gene name synonym)|uniprotkb:BET2(gene name)|psi-mi:BET2(display_short)|uniprotkb:YPR176C(locus name)|uniprotkb:P9705.12(orf name)	psi-mi:psmd6_human(display_long)|uniprotkb:PSMD6(gene name)|psi-mi:PSMD6(display_short)|uniprotkb:KIAA0107(gene name synonym)|uniprotkb:PFAAP4(gene name synonym)|uniprotkb:26S proteasome regulatory subunit S10(gene name synonym)|uniprotkb:p42A(gene name synonym)|uniprotkb:Proteasome regulatory particle subunit p44S10(gene name synonym)|uniprotkb:Phosphonoformate immuno-associated protein 4(gene name synonym)|uniprotkb:Breast cancer-associated protein SGA-113M(gene name synonym)|uniprotkb:26S proteasome regulatory subunit RPN7(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11523903|imex:IM-24995-167	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015502.1|sgd:S000006380|reactome:R-SCE-6803205|reactome:R-SCE-8873719|dip:DIP-2214N|ensemblfungi:YPR176C(gene)|ensemblfungi:YPR176C_mRNA(transcript)|go:"GO:0004663"(Rab geranylgeranyltransferase activity)|go:"GO:0005829"(cytosol)|go:"GO:0005968"(Rab-protein geranylgeranyltransferase complex)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0008270"(zinc ion binding)|go:"GO:0018342"(protein prenylation)|go:"GO:0018344"(protein geranylgeranylation)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001330(Prenyltransferase/squalene oxidase)|interpro:IPR008930(Terpenoid cylases/protein prenyltransferase alpha-alpha toroid)|interpro:IPR026873|sgd:YPR176C(identity)	refseq:NP_055629.1|ensembl:ENSG00000163636(gene)|ensembl:ENST00000295901(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019585|interpro:IPR035268|interpro:IPR036390|mint:Q15008|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4K|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSG|rcsb pdb:6MSH|reactome:R-HSA-5358346|reactome:R-HSA-1236978|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-1236974|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-69601|reactome:R-HSA-69481|refseq:NP_001258708.1|refseq:NP_001258709.1|refseq:NP_001258710.1|dip:DIP-27590N|entrezgene/locuslink:9861(identity)	-	crc64:6A9C44DFBE62AAFC	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Fxribu0N2yK6IA2GZDfO0YmqLAo559292	rogid:ULOM02v6J56vZLlAGn7wN3N6Efw9606	intact-crc:FCAF44B1895E29B1|rigid:fL/QqaO2d11ZBD1qWxfd5l+y8o8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
intact:EBI-11523890	uniprotkb:P20107	-	intact:EBI-29667|uniprotkb:D6W070|ensemblfungi:YMR243C	psi-mi:a0a087wwc3_human(display_short)|psi-mi:EBI-11523890(display_long)|uniprotkb:PDCL2(gene name)|psi-mi:PDCL2(display_short)	psi-mi:zrc1_yeast(display_long)|uniprotkb:ZRC1(gene name)|psi-mi:ZRC1(display_short)|uniprotkb:YM9408.05C(orf name)|uniprotkb:YMR243C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11523894|imex:IM-24995-166	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:A0A087WWC3(uniprot-removed-ac)|entrezgene/locuslink:132954(identity)	refseq:NP_013970.1|sgd:S000004856|dip:DIP-2030N|mint:P20107|ensemblfungi:YMR243C(gene)|ensemblfungi:YMR243C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005385"(zinc ion transmembrane transporter activity)|go:"GO:0006882"(cellular zinc ion homeostasis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0071577"(zinc ion transmembrane transport)|interpro:IPR002524(Cation efflux protein)|interpro:IPR027469|interpro:IPR036837|reactome:R-SCE-425410|reactome:R-SCE-435368|sgd:YMR243C(identity)	-	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:vhktqKnu+qJ9+neTG7Pkfxd3rG49606	rogid:ZZlCJ2Xj5Hiumdl3BNStZFS9qM4559292	intact-crc:499D2CCCB706B9DC|rigid:TdKuORqOHMmkfsvl18iHcBjb19M	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q5D1E8	uniprotkb:P20095	intact:EBI-747793|uniprotkb:Q6I9Z1|uniprotkb:Q9H5P1|uniprotkb:D3DPT0|ensembl:ENSP00000362179	intact:EBI-13820|ensemblfungi:YNR011C|uniprotkb:D6W1I6	psi-mi:zc12a_human(display_long)|uniprotkb:MCPIP(gene name synonym)|uniprotkb:MCPIP1(gene name synonym)|uniprotkb:ZC3H12A(gene name)|psi-mi:ZC3H12A(display_short)|uniprotkb:Monocyte chemotactic protein-induced protein 1(gene name synonym)|uniprotkb:Regnase-1(gene name synonym)|uniprotkb:Zinc finger CCCH domain-containing protein 12A(gene name synonym)	psi-mi:prp2_yeast(display_long)|uniprotkb:PRP2(gene name)|psi-mi:PRP2(display_short)|uniprotkb:RNA2(gene name synonym)|uniprotkb:YNR011C(locus name)|uniprotkb:N2048(orf name)|uniprotkb:Pre-mRNA-processing protein 2(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11523881|imex:IM-24995-165	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_079355.2|refseq:NP_001310479.1|ensembl:ENSG00000163874(gene)|ensembl:ENST00000373087(transcript)|go:"GO:0000294"(nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay)|go:"GO:0000932"(P-body)|go:"GO:0001525"(angiogenesis)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0002757"(immune response-activating signal transduction)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0004532"(exoribonuclease activity)|go:"GO:0004540"(ribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007399"(nervous system development)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010656"(negative regulation of muscle cell apoptotic process)|go:"GO:0010884"(positive regulation of lipid storage)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0030154"(cell differentiation)|go:"GO:0030867"(rough endoplasmic reticulum membrane)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032691"(negative regulation of interleukin-1 beta production)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035198"(miRNA binding)|go:"GO:0035613"(RNA stem-loop binding)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042406"(extrinsic component of endoplasmic reticulum membrane)|go:"GO:0043022"(ribosome binding)|go:"GO:0043031"(negative regulation of macrophage activation)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0044828"(negative regulation by host of viral genome replication)|go:"GO:0045019"(negative regulation of nitric oxide biosynthetic process)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051607"(defense response to virus)|go:"GO:0055118"(negative regulation of cardiac muscle contraction)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0090501"(RNA phosphodiester bond hydrolysis)|go:"GO:0090502"(RNA phosphodiester bond hydrolysis, endonucleolytic)|go:"GO:0098586"(cellular response to virus)|go:"GO:1900016"(negative regulation of cytokine production involved in inflammatory response)|go:"GO:1900119"(positive regulation of execution phase of apoptosis)|go:"GO:1901223"(negative regulation of NIK/NF-kappaB signaling)|go:"GO:1903003"(positive regulation of protein deubiquitination)|go:"GO:1903799"(negative regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1903936"(cellular response to sodium arsenite)|go:"GO:1904637"(cellular response to ionomycin)|go:"GO:1990869"(cellular response to chemokine)|go:"GO:2000320"(negative regulation of T-helper 17 cell differentiation)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|go:"GO:2000627"(positive regulation of miRNA catabolic process)|interpro:IPR021869|interpro:IPR040546|interpro:IPR040757|rcsb pdb:3V32|rcsb pdb:3V33|rcsb pdb:3V34|go:"GO:1900745"(positive regulation of p38MAPK cascade)|entrezgene/locuslink:80149(identity)	refseq:NP_014408.1|sgd:S000005294|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|rcsb pdb:5GM6|rcsb pdb:5LQW|rcsb pdb:7DCO|rcsb pdb:7DCP|rcsb pdb:7DCQ|rcsb pdb:7DCR|rcsb pdb:7DD3|go:"GO:0140603"(obsolete ATP hydrolysis activity)|ensemblfungi:YNR011C(gene)|ensemblfungi:YNR011C_mRNA(transcript)|go:"GO:0000349"(generation of catalytic spliceosome for first transesterification step)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0008186"(ATP-dependent activity, acting on RNA)|go:"GO:0034247"(snoRNA splicing)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|mint:P20095|dip:DIP-3961N|sgd:YNR011C(identity)	-	-	crc64:7EB3E1EE93215F57	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:3FqqH/XrYjHaa5oJpPXvfYwHKCQ9606	rogid:wfkc/eidpcEF1HlVabj2p/arPiY559292	intact-crc:A74FB3C9ACF194B6|rigid:1XVpLofLTzJg9RI/NFUp2L3C13M	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P20081	uniprotkb:Q9Y2W2	intact:EBI-6961|uniprotkb:D6W147|ensemblfungi:YNL135C	intact:EBI-714455|ensembl:ENSP00000261167|uniprotkb:Q96AY8	psi-mi:fkbp_yeast(display_long)|uniprotkb:RBP1(gene name synonym)|uniprotkb:N1213(orf name)|uniprotkb:N1845(orf name)|uniprotkb:YNL135C(locus name)|uniprotkb:FPR1(gene name)|psi-mi:FPR1(display_short)|uniprotkb:FKB1(gene name synonym)|uniprotkb:Peptidyl-prolyl cis-trans isomerase(gene name synonym)|uniprotkb:Rapamycin-binding protein(gene name synonym)	psi-mi:wbp11_human(display_long)|uniprotkb:SH3 domain-binding protein SNP70(gene name synonym)|uniprotkb:Npw38-binding protein(gene name synonym)|uniprotkb:WBP11(gene name)|psi-mi:WBP11(display_short)|uniprotkb:NPWBP(gene name synonym)|uniprotkb:SNP70(gene name synonym)|uniprotkb:SIPP1(gene name synonym)|uniprotkb:Splicing factor that interacts with PQBP-1 and PP1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11523872|imex:IM-24995-164	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014264.1|sgd:S000005079|dip:DIP-1263N|mint:P20081|ensemblfungi:YNL135C(gene)|ensemblfungi:YNL135C_mRNA(transcript)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005527"(macrolide binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006325"(chromatin organization)|go:"GO:0006457"(protein folding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:1901710"(regulation of homoserine biosynthetic process)|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)|rcsb pdb:1YAT|sgd:YNL135C(identity)	rcsb pdb:7ABG|reactome:R-HSA-72163|ensembl:ENSG00000084463(gene)|ensembl:ENST00000261167(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045292"(mRNA cis splicing, via spliceosome)|go:"GO:0050699"(WW domain binding)|interpro:IPR019007|mint:Q9Y2W2|rcsb pdb:7ABF|refseq:NP_057396.1|entrezgene/locuslink:51729(identity)	-	crc64:65C134830D300C06	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:8afvGSk+mPghtqkVoWd2rHJXXhQ559292	rogid:qE03bpSsQiJouJbn6ISt8DnD/pA9606	intact-crc:24A7A5F646089068|rigid:Yp9hgufBgRCAaH1qCnbXNzwHKb0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P21734	uniprotkb:Q9C040	intact:EBI-19717|uniprotkb:D6VSF9|ensemblfungi:YDR177W	intact:EBI-749840|uniprotkb:O60272|uniprotkb:Q9BSI9|uniprotkb:Q9UFZ1|ensembl:ENSP00000415812|ensembl:ENSP00000501586|ensembl:ENSP00000501612|ensembl:ENSP00000501652|ensembl:ENSP00000501662|ensembl:ENSP00000501792|ensembl:ENSP00000501822|ensembl:ENSP00000501951|ensembl:ENSP00000501994|ensembl:ENSP00000502089|ensembl:ENSP00000502114|ensembl:ENSP00000502159|ensembl:ENSP00000502273|ensembl:ENSP00000502348|ensembl:ENSP00000502356|ensembl:ENSP00000502519|ensembl:ENSP00000502543|ensembl:ENSP00000502676|uniprotkb:D3DP09	psi-mi:ubc1_yeast(display_long)|uniprotkb:UBC1(gene name)|psi-mi:UBC1(display_short)|uniprotkb:YDR177W(locus name)|uniprotkb:YD9395.10(orf name)|uniprotkb:Ubiquitin-protein ligase(gene name synonym)|uniprotkb:Ubiquitin carrier protein(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-24 kDa(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme 1(gene name synonym)	psi-mi:trim2_human(display_long)|uniprotkb:RING finger protein 86(gene name synonym)|uniprotkb:TRIM2(gene name)|psi-mi:TRIM2(display_short)|uniprotkb:KIAA0517(gene name synonym)|uniprotkb:RNF86(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM2(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase TRIM2(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11523977|imex:IM-24995-175	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002584|ensemblfungi:YDR177W(gene)|ensemblfungi:YDR177W_mRNA(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016050"(vesicle organization)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070628"(proteasome binding)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR009060(UBA-like)|interpro:IPR015368(Ubiquitin-conjugating enzyme, C-terminal fungi)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1FXT|rcsb pdb:1FZY|rcsb pdb:1TTE|reactome:R-SCE-8866652|reactome:R-SCE-983168|refseq:NP_010462.3|dip:DIP-6594N|mint:P21734|sgd:YDR177W(identity)	refseq:NP_001123539.1|refseq:NP_056086.2|ensembl:ENST00000437508(transcript)|ensembl:ENST00000674874(transcript)|ensembl:ENST00000674876(transcript)|ensembl:ENSG00000109654(gene)|refseq:XP_016863433.1|refseq:XP_016863434.1|refseq:XP_016863437.1|refseq:XP_016863438.1|refseq:XP_016863439.1|refseq:XP_016863440.1|refseq:XP_016863441.1|ensembl:ENST00000674976(transcript)|ensembl:ENST00000675054(transcript)|ensembl:ENST00000675159(transcript)|ensembl:ENST00000675293(transcript)|ensembl:ENST00000675315(transcript)|ensembl:ENST00000675384(transcript)|ensembl:ENST00000675745(transcript)|ensembl:ENST00000675835(transcript)|ensembl:ENST00000676172(transcript)|ensembl:ENST00000676252(transcript)|ensembl:ENST00000676264(transcript)|ensembl:ENST00000676348(transcript)|ensembl:ENST00000676374(transcript)|ensembl:ENST00000676423(transcript)|ensembl:ENST00000676458(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017868|interpro:IPR017907|interpro:IPR027370|mint:Q9C040|rcsb pdb:7B2R|reactome:R-HSA-877300|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001258(NHL repeat)|interpro:IPR001298(Filamin/ABP280 repeat)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR013017(NHL repeat, subgroup)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|entrezgene/locuslink:23321(identity)	-	crc64:899CC397A1285145	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:3N1WHZJcgMeK0OglGpGI2m4XU8Q559292	rogid:vcyraMhX0YqrCi9PXhvlJ7QqhGs9606	intact-crc:36AED4960102862F|rigid:U5sD2HuFEJJxijpgqcIgCEoEveU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O95376	uniprotkb:P21734	intact:EBI-711158|uniprotkb:Q9HBZ6|uniprotkb:Q9UEM9|ensembl:ENSP00000348769|ensembl:ENSP00000403222	intact:EBI-19717|uniprotkb:D6VSF9|ensemblfungi:YDR177W	psi-mi:ari2_human(display_long)|uniprotkb:Triad1 protein(gene name synonym)|uniprotkb:ARIH2(gene name)|psi-mi:ARIH2(display_short)|uniprotkb:ARI2(gene name synonym)|uniprotkb:TRIAD1(gene name synonym)|uniprotkb:HT005(orf name)|uniprotkb:RING-type E3 ubiquitin transferase ARIH2(gene name synonym)	psi-mi:ubc1_yeast(display_long)|uniprotkb:UBC1(gene name)|psi-mi:UBC1(display_short)|uniprotkb:YDR177W(locus name)|uniprotkb:YD9395.10(orf name)|uniprotkb:Ubiquitin-protein ligase(gene name synonym)|uniprotkb:Ubiquitin carrier protein(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-24 kDa(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme 1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11523968|imex:IM-24995-174	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001304262.1|refseq:NP_001304263.1|refseq:NP_006312.1|ensembl:ENSG00000177479(gene)|ensembl:ENST00000356401(transcript)|ensembl:ENST00000449376(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0048588"(developmental cell growth)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0071425"(hematopoietic stem cell proliferation)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002867(Zinc finger, C6HC-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR031126|interpro:IPR031127|interpro:IPR044066|reactome:R-HSA-983168|refseq:XP_016861020.1|refseq:XP_016861021.1|entrezgene/locuslink:10425(identity)	sgd:S000002584|ensemblfungi:YDR177W(gene)|ensemblfungi:YDR177W_mRNA(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016050"(vesicle organization)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070628"(proteasome binding)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR009060(UBA-like)|interpro:IPR015368(Ubiquitin-conjugating enzyme, C-terminal fungi)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1FXT|rcsb pdb:1FZY|rcsb pdb:1TTE|reactome:R-SCE-8866652|reactome:R-SCE-983168|refseq:NP_010462.3|dip:DIP-6594N|mint:P21734|sgd:YDR177W(identity)	-	-	crc64:899CC397A1285145	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:536Qu2bpbptYcIhxoeLJNTErLTM9606	rogid:3N1WHZJcgMeK0OglGpGI2m4XU8Q559292	intact-crc:EBCF13D0E720039A|rigid:j7z9megFLIB4albVuagtbf0OQ80	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q08379	uniprotkb:P20676	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	intact:EBI-12392|ensemblfungi:YOR098C|uniprotkb:D6W2F9	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:nup1_yeast(display_long)|uniprotkb:NUP1(gene name)|psi-mi:NUP1(display_short)|uniprotkb:YOR098C(locus name)|uniprotkb:YOR3182C(orf name)|uniprotkb:Nuclear pore protein NUP1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11523930|imex:IM-24995-170	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N|entrezgene/locuslink:2801(identity)	ensemblfungi:YOR098C(gene)|ensemblfungi:YOR098C_mRNA(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000972"(transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0005643"(nuclear pore)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0044615"(nuclear pore nuclear basket)|interpro:IPR026054|rcsb pdb:4C31|rcsb pdb:4MBE|rcsb pdb:5OWU|go:"GO:0006607"(NLS-bearing protein import into nucleus)|refseq:NP_014741.1|sgd:S000005624|mint:P20676|dip:DIP-81N|sgd:YOR098C(identity)	-	-	crc64:4AC23567D2FB53CC	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2017/05/26	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	rogid:X1AjTIzoXjQ7vXlKzI88m7xfu6w559292	intact-crc:D8BBA9E4DD851426|rigid:NiqQjTaP3EVF+eZ72FYDbdhmnC8	false	sufficient binding region:383-1002	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96IK5	uniprotkb:P21651	intact:EBI-2548508|ensembl:ENSP00000282570|uniprotkb:Q9H826|uniprotkb:Q9H8V7|uniprotkb:Q9H927	intact:EBI-10742|ensemblfungi:YJR021C|uniprotkb:D6VWJ5	psi-mi:gmcl1_human(display_long)|uniprotkb:GMCL1(gene name)|psi-mi:GMCL1(display_short)|uniprotkb:GCL(gene name synonym)|uniprotkb:BTBD13(gene name synonym)|uniprotkb:SPATA29(gene name synonym)|uniprotkb:Spermatogenesis-associated protein 29(gene name synonym)	psi-mi:re107_yeast(display_long)|uniprotkb:MER2(gene name synonym)|uniprotkb:J1462(orf name)|uniprotkb:YJR021C(locus name)|uniprotkb:REC107(gene name)|psi-mi:REC107(display_short)|uniprotkb:Meiotic recombination protein 2(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11523950|imex:IM-24995-172	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000087338(gene)|ensembl:ENST00000282570(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0007281"(germ cell development)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016363"(nuclear matrix)|go:"GO:0042802"(identical protein binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR043380|refseq:NP_848526.1|entrezgene/locuslink:64395(identity)	ensemblfungi:YJR021C(gene)|ensemblfungi:YJR021C_mRNA(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0042802"(identical protein binding)|interpro:IPR015159(Mer2)|sgd:S000003782|refseq:NP_012555.1|dip:DIP-5265N|sgd:YJR021C(identity)	-	-	crc64:46F426AC0DFDFAD0	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:ED8yqySVu7BWxpw3DUSNBZSQWrk9606	rogid:v9kR3rBIptwb/cZE7B5IMAkYWKc559292	intact-crc:5C792CD78F55AC3D|rigid:bOFaBcDqb6RObTx/Mdo/KzneuAU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P20676	uniprotkb:P51116	intact:EBI-12392|ensemblfungi:YOR098C|uniprotkb:D6W2F9	intact:EBI-740459|uniprotkb:Q8WUM2|uniprotkb:Q86V09|uniprotkb:B2R9M2|uniprotkb:D3DTQ1|ensembl:ENSP00000250113	psi-mi:nup1_yeast(display_long)|uniprotkb:NUP1(gene name)|psi-mi:NUP1(display_short)|uniprotkb:YOR098C(locus name)|uniprotkb:YOR3182C(orf name)|uniprotkb:Nuclear pore protein NUP1(gene name synonym)	psi-mi:fxr2_human(display_long)|uniprotkb:FXR2(gene name)|psi-mi:FXR2(display_short)|uniprotkb:FMR1L2(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11523941|imex:IM-24995-171	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YOR098C(gene)|ensemblfungi:YOR098C_mRNA(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000972"(transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0005643"(nuclear pore)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0044615"(nuclear pore nuclear basket)|interpro:IPR026054|rcsb pdb:4C31|rcsb pdb:4MBE|rcsb pdb:5OWU|go:"GO:0006607"(NLS-bearing protein import into nucleus)|refseq:NP_014741.1|sgd:S000005624|mint:P20676|dip:DIP-81N|sgd:YOR098C(identity)	interpro:IPR004087(K Homology)|refseq:NP_004851.2|ensembl:ENSG00000129245(gene)|ensembl:ENST00000250113(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0044326"(dendritic spine neck)|go:"GO:0045182"(translation regulator activity)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0098793"(presynapse)|go:"GO:1902737"(dendritic filopodium)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|interpro:IPR004088(K Homology, type 1)|interpro:IPR008395(Agenet)|interpro:IPR022034|interpro:IPR032172|interpro:IPR036612|interpro:IPR040148|interpro:IPR040472|interpro:IPR041560|mint:P51116|rcsb pdb:3H8Z|entrezgene/locuslink:9513(identity)	-	crc64:4AC23567D2FB53CC	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:X1AjTIzoXjQ7vXlKzI88m7xfu6w559292	rogid:NnYgyzD2NRGIO1ZHukr5qy44qRE9606	intact-crc:F2BC7D2FC67AC20E|rigid:EiytHB1z8daib+C292mqC/9Yc/o	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9HD26-2	uniprotkb:P21651	intact:EBI-11102276|ensembl:ENSP00000052569	intact:EBI-10742|ensemblfungi:YJR021C|uniprotkb:D6VWJ5	psi-mi:q9hd26-2(display_long)|uniprotkb:GOPC(gene name)|psi-mi:GOPC(display_short)|uniprotkb:CAL(gene name synonym)|uniprotkb:CFTR-associated ligand(gene name synonym)|uniprotkb:FIG(gene name synonym)|uniprotkb:Fused in glioblastoma(gene name synonym)|uniprotkb:PDZ protein interacting specifically with TC10(gene name synonym)	psi-mi:re107_yeast(display_long)|uniprotkb:MER2(gene name synonym)|uniprotkb:J1462(orf name)|uniprotkb:YJR021C(locus name)|uniprotkb:REC107(gene name)|psi-mi:REC107(display_short)|uniprotkb:Meiotic recombination protein 2(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11523959|imex:IM-24995-173	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000047932(gene)|ensembl:ENST00000052569(transcript)|intact:EBI-349832(isoform-parent)|uniprotkb:Q9HD26-2(isoform-parent)|entrezgene/locuslink:57120(identity)	ensemblfungi:YJR021C(gene)|ensemblfungi:YJR021C_mRNA(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0042802"(identical protein binding)|interpro:IPR015159(Mer2)|sgd:S000003782|refseq:NP_012555.1|dip:DIP-5265N|sgd:YJR021C(identity)	-	-	crc64:46F426AC0DFDFAD0	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:QoEGY54FfmwTrpGVMQN9ASGPgVI9606	rogid:v9kR3rBIptwb/cZE7B5IMAkYWKc559292	intact-crc:CCD0A7131376555C|rigid:GfCz05Or0PqXzJLkD4GZ2URvuhY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P22803	uniprotkb:Q8TBB1	intact:EBI-19598|uniprotkb:D6VUZ2|ensemblfungi:YGR209C	intact:EBI-739832|uniprotkb:Q4W5K7|uniprotkb:Q8N4C2|uniprotkb:Q96MJ7|uniprotkb:Q9BY20|ensembl:ENSP00000263925	psi-mi:trx2_yeast(display_long)|uniprotkb:TRX2(gene name)|psi-mi:TRX2(display_short)|uniprotkb:TRX1(gene name synonym)|uniprotkb:G7746(orf name)|uniprotkb:YGR209C(locus name)|uniprotkb:Thioredoxin II(gene name synonym)|uniprotkb:Thioredoxin-1(gene name synonym)	psi-mi:lnx1_human(display_long)|uniprotkb:LNX1(gene name)|psi-mi:LNX1(display_short)|uniprotkb:LNX(gene name synonym)|uniprotkb:Numb-binding protein 1(gene name synonym)|uniprotkb:Ligand of Numb-protein X 1(gene name synonym)|uniprotkb:PDZ domain-containing RING finger protein 2(gene name synonym)|uniprotkb:PDZRN2(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase LNX(gene name synonym)|uniprotkb:UNQ574/PRO1136(orf name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11524023|imex:IM-24995-180	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003441|go:"GO:0009263"(deoxyribonucleotide biosynthetic process)|go:"GO:0015031"(protein transport)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0015036"(disulfide oxidoreductase activity)|go:"GO:0042144"(vacuole fusion, non-autophagic)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0080058"(protein deglutathionylation)|interpro:IPR005746(Thioredoxin)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017937|interpro:IPR036249|rcsb pdb:2FA4|rcsb pdb:2HSY|rcsb pdb:3PIN|rcsb pdb:4DSS|rcsb pdb:7BVV|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|ensemblfungi:YGR209C(gene)|ensemblfungi:YGR209C_mRNA(transcript)|go:"GO:0000011"(vacuole inheritance)|go:"GO:0000103"(sulfate assimilation)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006662"(glycerol ether metabolic process)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|refseq:NP_011725.3|dip:DIP-5552N|mint:P22803|sgd:YGR209C(identity)	refseq:NP_001119800.1|refseq:NP_116011.2|refseq:XP_005265842.1|refseq:XP_016864265.1|ensembl:ENSG00000072201(gene)|ensembl:ENST00000263925(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR036034|mint:Q8TBB1|rcsb pdb:3B76|rcsb pdb:5H7R|rcsb pdb:5H7S|reactome:R-HSA-983168|entrezgene/locuslink:84708(identity)	-	crc64:071503762C90D451	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:pRt9fGROPXW+o4g6ynOmCDiclFk559292	rogid:tWvePnVxh9yxWl8nQd3KZhCSKKo9606	intact-crc:B2FC3D622D36CD15|rigid:MqEiw6U/WmcKG7kZPaq/vJFAgWQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P22354	uniprotkb:O95273	intact:EBI-15536|uniprotkb:D6VXE5|ensemblfungi:YKR085C	intact:EBI-748961|uniprotkb:A8K3Q0|uniprotkb:A8K3U2|uniprotkb:Q6ZQN9|uniprotkb:Q7Z519|uniprotkb:Q8NBS7|uniprotkb:Q8NBY2|uniprotkb:Q9NS19|uniprotkb:Q9NYH3|uniprotkb:Q9UHX9|ensembl:ENSP00000300213	psi-mi:rm20_yeast(display_long)|uniprotkb:MRPL20(gene name)|psi-mi:MRPL20(display_short)|uniprotkb:YKR085C(locus name)|uniprotkb:YKR405(orf name)|uniprotkb:YmL20(gene name synonym)|uniprotkb:Mitochondrial large ribosomal subunit protein mL58(gene name synonym)	psi-mi:ccdb1_human(display_long)|uniprotkb:Grap2 and cyclin-D-interacting protein(gene name synonym)|uniprotkb:Human homolog of Maid(gene name synonym)|uniprotkb:CCNDBP1(gene name)|psi-mi:CCNDBP1(display_short)|uniprotkb:DIP1(gene name synonym)|uniprotkb:GCIP(gene name synonym)|uniprotkb:HHM(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11524014|imex:IM-24995-179	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013011.1|sgd:S000001793|rcsb pdb:5MRE|rcsb pdb:5MRF|ensemblfungi:YKR085C(gene)|ensemblfungi:YKR085C_mRNA(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR024388|rcsb pdb:3J6B|rcsb pdb:5MRC|dip:DIP-6793N|mint:P22354|sgd:YKR085C(identity)	refseq:NP_036274.3|ensembl:ENSG00000166946(gene)|ensembl:ENST00000300213(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0016604"(nuclear body)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR026907|mint:O95273|rcsb pdb:3AY5|entrezgene/locuslink:23582(identity)	-	crc64:3165663C8C19EC60	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:DkeQ+P79JhbEGKxUK2g8JXvgBSA559292	rogid:Vi9aoFc+Mov6P3X6KGmsTxXqxvM9606	intact-crc:4C53322C4E17649E|rigid:PvXhIWJN9xYnvSkM9aLFQuOQjXQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9HCM9-2	uniprotkb:P21734	intact:EBI-11523450|ensembl:ENSP00000365847|ensembl:ENSP00000373095|ensembl:ENSP00000373097|ensembl:ENSP00000379797|ensembl:ENSP00000379800|ensembl:ENSP00000383486|ensembl:ENSP00000387445|ensembl:ENSP00000389198|ensembl:ENSP00000389852|ensembl:ENSP00000392130|ensembl:ENSP00000394353|ensembl:ENSP00000396986|ensembl:ENSP00000398956|ensembl:ENSP00000401071|ensembl:ENSP00000401184|ensembl:ENSP00000404340|ensembl:ENSP00000404904|ensembl:ENSP00000411582|ensembl:ENSP00000412743|ensembl:ENSP00000414525|ensembl:ENSP00000415259	intact:EBI-19717|uniprotkb:D6VSF9|ensemblfungi:YDR177W	psi-mi:q9hcm9-2(display_long)|uniprotkb:TRIM39(gene name)|psi-mi:TRIM39(display_short)|uniprotkb:RING finger protein 23(gene name synonym)|uniprotkb:RNF23(gene name synonym)|uniprotkb:TFP(gene name synonym)|uniprotkb:Testis-abundant finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 39(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM39(gene name synonym)|uniprotkb:TIM39beta(isoform synonym)	psi-mi:ubc1_yeast(display_long)|uniprotkb:UBC1(gene name)|psi-mi:UBC1(display_short)|uniprotkb:YDR177W(locus name)|uniprotkb:YD9395.10(orf name)|uniprotkb:Ubiquitin-protein ligase(gene name synonym)|uniprotkb:Ubiquitin carrier protein(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-24 kDa(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme 1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11523986|imex:IM-24995-176	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-739510(isoform-parent)|ensembl:ENSG00000204599(gene)|ensembl:ENSG00000206495(gene)|ensembl:ENSG00000224994(gene)|ensembl:ENSG00000226437(gene)|ensembl:ENSG00000229929(gene)|ensembl:ENSG00000230308(gene)|ensembl:ENSG00000232839(gene)|ensembl:ENST00000376659(transcript)|ensembl:ENST00000383601(transcript)|ensembl:ENST00000383603(transcript)|ensembl:ENST00000396548(transcript)|ensembl:ENST00000396551(transcript)|ensembl:ENST00000400644(transcript)|ensembl:ENST00000414015(transcript)|ensembl:ENST00000419790(transcript)|ensembl:ENST00000430502(transcript)|ensembl:ENST00000431272(transcript)|ensembl:ENST00000433900(transcript)|ensembl:ENST00000438076(transcript)|ensembl:ENST00000438859(transcript)|ensembl:ENST00000440117(transcript)|ensembl:ENST00000443109(transcript)|ensembl:ENST00000446397(transcript)|ensembl:ENST00000449318(transcript)|ensembl:ENST00000450778(transcript)|ensembl:ENST00000451132(transcript)|ensembl:ENST00000452705(transcript)|ensembl:ENST00000458607(transcript)|uniprotkb:Q9HCM9-2(isoform-parent)|entrezgene/locuslink:56658(identity)	sgd:S000002584|ensemblfungi:YDR177W(gene)|ensemblfungi:YDR177W_mRNA(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016050"(vesicle organization)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070628"(proteasome binding)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR009060(UBA-like)|interpro:IPR015368(Ubiquitin-conjugating enzyme, C-terminal fungi)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1FXT|rcsb pdb:1FZY|rcsb pdb:1TTE|reactome:R-SCE-8866652|reactome:R-SCE-983168|refseq:NP_010462.3|dip:DIP-6594N|mint:P21734|sgd:YDR177W(identity)	-	-	crc64:899CC397A1285145	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:UfSn2+IVRxtGomVeDGdZpL7mz5I9606	rogid:3N1WHZJcgMeK0OglGpGI2m4XU8Q559292	intact-crc:2E4BFD2E6737960E|rigid:diOzZx6LRU1fphQaRrHjmYvYAd0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q15437	uniprotkb:P22215	intact:EBI-742673|uniprotkb:Q5W183|uniprotkb:Q9BS15|uniprotkb:Q9BSI2|uniprotkb:Q9H1D7|intact:EBI-1048165|uniprotkb:Q503A9|uniprotkb:D3DW33|ensembl:ENSP00000262544|ensembl:ENSP00000338844|ensembl:ENSP00000366685|ensembl:ENSP00000497473	intact:EBI-17397|uniprotkb:D6W307|ensemblfungi:YOR307C	psi-mi:sc23b_human(display_long)|uniprotkb:SEC23-related protein B(gene name synonym)|uniprotkb:SEC23B(gene name)|psi-mi:SEC23B(display_short)	psi-mi:sly41_yeast(display_long)|uniprotkb:O5663(orf name)|uniprotkb:YOR307C(locus name)|uniprotkb:SLY41(gene name)|psi-mi:SLY41(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11523996|imex:IM-24995-177	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001166216.1|refseq:NP_006354.2|refseq:NP_116780.1|refseq:NP_116781.1|ensembl:ENSG00000101310(gene)|ensembl:ENST00000262544(transcript)|ensembl:ENST00000336714(transcript)|ensembl:ENST00000377465(transcript)|ensembl:ENST00000650089(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008270"(zinc ion binding)|go:"GO:0012505"(endomembrane system)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0090110"(COPII-coated vesicle cargo loading)|go:"GO:0070971"(endoplasmic reticulum exit site)|interpro:IPR006895(Zinc finger, Sec23/Sec24-type)|interpro:IPR006896(Sec23/Sec24 trunk region)|interpro:IPR006900(Sec23/Sec24 helical region)|interpro:IPR007123(Gelsolin region)|interpro:IPR012990(Sec23/Sec24 beta-sandwich)|interpro:IPR029006|interpro:IPR036174|interpro:IPR036175|interpro:IPR036180|interpro:IPR036465|interpro:IPR037364|interpro:IPR037550|mint:Q15437|refseq:XP_016883082.1|entrezgene/locuslink:10483(identity)	refseq:NP_014952.1|sgd:S000005834|ensemblfungi:YOR307C(gene)|ensemblfungi:YOR307C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0015297"(antiporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0089721"(phosphoenolpyruvate transmembrane transporter activity)|go:"GO:1990536"(phosphoenolpyruvate transmembrane import into Golgi lumen)|interpro:IPR004696(Tpt phosphate/phosphoenolpyruvate translocator)|interpro:IPR004853(Protein of unknown function DUF250)|dip:DIP-2919N|sgd:YOR307C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:+3KZ/1jjziSgJRcr81Axquofkl49606	rogid:ZlrKRnUmlnFI2o8e365rgea//gA559292	intact-crc:EC5D18868A348D93|rigid:CEqncGa+9X+oy3T+p0p0cAwbhdo	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96D03	uniprotkb:P22217	intact:EBI-742054|uniprotkb:B2R7C3|ensembl:ENSP00000354830	intact:EBI-19607|uniprotkb:D6VY45|ensemblfungi:YLR043C	psi-mi:ddt4l_human(display_long)|uniprotkb:Protein regulated in development and DNA damage response 2(gene name synonym)|uniprotkb:HIF-1 responsive protein RTP801-like(gene name synonym)|uniprotkb:DDIT4L(gene name)|psi-mi:DDIT4L(display_short)|uniprotkb:REDD2(gene name synonym)|uniprotkb:RTP801L(gene name synonym)	psi-mi:trx1_yeast(display_long)|uniprotkb:TRX1(gene name)|psi-mi:TRX1(display_short)|uniprotkb:TRX2(gene name synonym)|uniprotkb:YLR043C(locus name)|uniprotkb:Thioredoxin I(gene name synonym)|uniprotkb:Thioredoxin-2(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11524005|imex:IM-24995-178	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_660287.1|ensembl:ENSG00000145358(gene)|ensembl:ENST00000273990(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0009968"(negative regulation of signal transduction)|interpro:IPR012918(RTP801, C-terminal)|interpro:IPR038281|entrezgene/locuslink:115265(identity)	refseq:NP_013144.1|sgd:S000004033|interpro:IPR005746(Thioredoxin)|interpro:IPR017937|interpro:IPR013766(Thioredoxin domain)|ensemblfungi:YLR043C(gene)|ensemblfungi:YLR043C_mRNA(transcript)|go:"GO:0000011"(vacuole inheritance)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0009263"(deoxyribonucleotide biosynthetic process)|go:"GO:0015031"(protein transport)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0015036"(disulfide oxidoreductase activity)|go:"GO:0042144"(vacuole fusion, non-autophagic)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0080058"(protein deglutathionylation)|rcsb pdb:2I9H|rcsb pdb:2N5A|rcsb pdb:2N5B|rcsb pdb:3F3Q|rcsb pdb:3F3R|go:"GO:0006662"(glycerol ether metabolic process)|mint:P22217|interpro:IPR036249|sgd:YLR043C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:DHXiWraTchl3LZgh/lXlUr3LKwE9606	rogid:HTTjl3NGIuQllhjAI5NASyqqIlc559292	intact-crc:E24DA78B43BF7A2C|rigid:Yyhl69PcyPOAWqvyRxqGPz4VrB8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P23059	uniprotkb:Q9UKT9	intact:EBI-10950|ensemblfungi:YCR020C-A|uniprotkb:D6VR29	intact:EBI-747204|uniprotkb:Q8WWQ9|uniprotkb:Q8WWR0|uniprotkb:Q8WWR1|uniprotkb:Q8WWR2|uniprotkb:Q8WWR3|uniprotkb:Q8N574|uniprotkb:B4DVV5|uniprotkb:Q69BL6|uniprotkb:Q69BL7|uniprotkb:Q69BL8|uniprotkb:Q69BL9|uniprotkb:Q69BM0|uniprotkb:Q69BM1|uniprotkb:Q69BM2|uniprotkb:Q69BM3|uniprotkb:Q69BM5|ensembl:ENSP00000344544	psi-mi:naa38_yeast(display_long)|uniprotkb:MAK31(gene name)|psi-mi:MAK31(display_short)|uniprotkb:YCR020C-A(locus name)|uniprotkb:YCR20C-A(orf name)|uniprotkb:L-A virus GAG protein N-acetyltransferase subunit MAK31(gene name synonym)|uniprotkb:Maintenance of killer protein 31(gene name synonym)|uniprotkb:NAA38(gene name synonym)|uniprotkb:N-terminal acetyltransferase C complex subunit MAK31(gene name synonym)	psi-mi:ikzf3_human(display_long)|uniprotkb:ZNFN1A3(gene name synonym)|uniprotkb:Ikaros family zinc finger protein 3(gene name synonym)|uniprotkb:IKZF3(gene name)|psi-mi:IKZF3(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11524072|imex:IM-24995-185	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YCR020C-A(gene)|ensemblfungi:YCR020C-A_mRNA(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005688"(U6 snRNP)|go:"GO:0005829"(cytosol)|go:"GO:0006474"(N-terminal protein amino acid acetylation)|go:"GO:0016070"(RNA metabolic process)|go:"GO:0031417"(NatC complex)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071011"(precatalytic spliceosome)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR034110|rcsb pdb:6YGA|rcsb pdb:6YGB|rcsb pdb:6YGC|rcsb pdb:6YGD|refseq:NP_009948.1|sgd:S000000614|mint:P23059|dip:DIP-1429N|sgd:YCR020C-A(identity)	refseq:NP_001271443.1|refseq:NP_001271444.1|refseq:NP_036613.2|refseq:NP_899051.1|refseq:NP_899052.1|refseq:NP_899053.1|refseq:NP_899054.1|refseq:NP_899055.1|refseq:NP_001271445.1|refseq:NP_001244337.1|refseq:NP_001244338.1|refseq:NP_001244339.1|refseq:NP_001244340.1|refseq:NP_001244341.1|refseq:NP_001244342.1|refseq:NP_001244343.1|ensembl:ENSG00000161405(gene)|ensembl:ENST00000346872(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007498"(mesoderm development)|go:"GO:0009617"(response to bacterium)|go:"GO:0030888"(regulation of B cell proliferation)|go:"GO:0042113"(B cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045577"(regulation of B cell differentiation)|go:"GO:0045619"(regulation of lymphocyte differentiation)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|go:"GO:0046872"(metal ion binding)|dip:DIP-56975N|entrezgene/locuslink:22806(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:VUwG0xxj0NeyZKANRYCAgJGuqs8559292	rogid:2Kp6LefSLfK5VIiE6DmQusFIfMY9606	intact-crc:04854D65C6A1FB9A|rigid:7/DvT/1dtf1pZQqfsZaJOCyhnUI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UJV3-2	uniprotkb:P23059	intact:EBI-10172526|ensembl:ENSP00000413976	intact:EBI-10950|ensemblfungi:YCR020C-A|uniprotkb:D6VR29	psi-mi:q9ujv3-2(display_long)|uniprotkb:RING-type E3 ubiquitin transferase MID2(gene name synonym)|uniprotkb:FXY2(gene name synonym)|uniprotkb:Midin-2(gene name synonym)|uniprotkb:Midline defect 2(gene name synonym)|uniprotkb:Midline-2(gene name synonym)|uniprotkb:RING finger protein 60(gene name synonym)|uniprotkb:RNF60(gene name synonym)|uniprotkb:TRIM1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 1(gene name synonym)|uniprotkb:MID2(gene name)|psi-mi:MID2(display_short)	psi-mi:naa38_yeast(display_long)|uniprotkb:MAK31(gene name)|psi-mi:MAK31(display_short)|uniprotkb:YCR020C-A(locus name)|uniprotkb:YCR20C-A(orf name)|uniprotkb:L-A virus GAG protein N-acetyltransferase subunit MAK31(gene name synonym)|uniprotkb:Maintenance of killer protein 31(gene name synonym)|uniprotkb:NAA38(gene name synonym)|uniprotkb:N-terminal acetyltransferase C complex subunit MAK31(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11524061|imex:IM-24995-184	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-751983(isoform-parent)|uniprotkb:Q9UJV3-2(isoform-parent)|ensembl:ENSG00000080561(gene)|ensembl:ENST00000443968(transcript)|entrezgene/locuslink:11043(identity)	ensemblfungi:YCR020C-A(gene)|ensemblfungi:YCR020C-A_mRNA(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005688"(U6 snRNP)|go:"GO:0005829"(cytosol)|go:"GO:0006474"(N-terminal protein amino acid acetylation)|go:"GO:0016070"(RNA metabolic process)|go:"GO:0031417"(NatC complex)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071011"(precatalytic spliceosome)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR034110|rcsb pdb:6YGA|rcsb pdb:6YGB|rcsb pdb:6YGC|rcsb pdb:6YGD|refseq:NP_009948.1|sgd:S000000614|mint:P23059|dip:DIP-1429N|sgd:YCR020C-A(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:/FJ+V2H7SaWon7caUWkEkmHFVxQ9606	rogid:VUwG0xxj0NeyZKANRYCAgJGuqs8559292	intact-crc:81316A9F8AFE57DC|rigid:UHUc4T8tYrgIDj6hGi2K0oJGCYk	false	sufficient binding region:21-705	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96D03	uniprotkb:P22803	intact:EBI-742054|uniprotkb:B2R7C3|ensembl:ENSP00000354830	intact:EBI-19598|uniprotkb:D6VUZ2|ensemblfungi:YGR209C	psi-mi:ddt4l_human(display_long)|uniprotkb:Protein regulated in development and DNA damage response 2(gene name synonym)|uniprotkb:HIF-1 responsive protein RTP801-like(gene name synonym)|uniprotkb:DDIT4L(gene name)|psi-mi:DDIT4L(display_short)|uniprotkb:REDD2(gene name synonym)|uniprotkb:RTP801L(gene name synonym)	psi-mi:trx2_yeast(display_long)|uniprotkb:TRX2(gene name)|psi-mi:TRX2(display_short)|uniprotkb:TRX1(gene name synonym)|uniprotkb:G7746(orf name)|uniprotkb:YGR209C(locus name)|uniprotkb:Thioredoxin II(gene name synonym)|uniprotkb:Thioredoxin-1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11524032|imex:IM-24995-181	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_660287.1|ensembl:ENSG00000145358(gene)|ensembl:ENST00000273990(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0009968"(negative regulation of signal transduction)|interpro:IPR012918(RTP801, C-terminal)|interpro:IPR038281|entrezgene/locuslink:115265(identity)	sgd:S000003441|go:"GO:0009263"(deoxyribonucleotide biosynthetic process)|go:"GO:0015031"(protein transport)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0015036"(disulfide oxidoreductase activity)|go:"GO:0042144"(vacuole fusion, non-autophagic)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0080058"(protein deglutathionylation)|interpro:IPR005746(Thioredoxin)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017937|interpro:IPR036249|rcsb pdb:2FA4|rcsb pdb:2HSY|rcsb pdb:3PIN|rcsb pdb:4DSS|rcsb pdb:7BVV|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|ensemblfungi:YGR209C(gene)|ensemblfungi:YGR209C_mRNA(transcript)|go:"GO:0000011"(vacuole inheritance)|go:"GO:0000103"(sulfate assimilation)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006662"(glycerol ether metabolic process)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|refseq:NP_011725.3|dip:DIP-5552N|mint:P22803|sgd:YGR209C(identity)	-	-	crc64:071503762C90D451	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:DHXiWraTchl3LZgh/lXlUr3LKwE9606	rogid:pRt9fGROPXW+o4g6ynOmCDiclFk559292	intact-crc:73C94FD3C8D59F6E|rigid:8t0PJQHcNgIXZyZ5Zhffs+CPVkg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P23059	uniprotkb:Q13422-7	intact:EBI-10950|ensemblfungi:YCR020C-A|uniprotkb:D6VR29	intact:EBI-11522367|ensembl:ENSP00000352123|ensembl:ENSP00000413025	psi-mi:naa38_yeast(display_long)|uniprotkb:MAK31(gene name)|psi-mi:MAK31(display_short)|uniprotkb:YCR020C-A(locus name)|uniprotkb:YCR20C-A(orf name)|uniprotkb:L-A virus GAG protein N-acetyltransferase subunit MAK31(gene name synonym)|uniprotkb:Maintenance of killer protein 31(gene name synonym)|uniprotkb:NAA38(gene name synonym)|uniprotkb:N-terminal acetyltransferase C complex subunit MAK31(gene name synonym)	psi-mi:q13422-7(display_long)|uniprotkb:IKZF1(gene name)|psi-mi:IKZF1(display_short)|uniprotkb:IK1(gene name synonym)|uniprotkb:IKAROS(gene name synonym)|uniprotkb:Ikaros family zinc finger protein 1(gene name synonym)|uniprotkb:LYF1(gene name synonym)|uniprotkb:Lymphoid transcription factor LyF-1(gene name synonym)|uniprotkb:ZNFN1A1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11524041|imex:IM-24995-182	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YCR020C-A(gene)|ensemblfungi:YCR020C-A_mRNA(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005688"(U6 snRNP)|go:"GO:0005829"(cytosol)|go:"GO:0006474"(N-terminal protein amino acid acetylation)|go:"GO:0016070"(RNA metabolic process)|go:"GO:0031417"(NatC complex)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071011"(precatalytic spliceosome)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR034110|rcsb pdb:6YGA|rcsb pdb:6YGB|rcsb pdb:6YGC|rcsb pdb:6YGD|refseq:NP_009948.1|sgd:S000000614|mint:P23059|dip:DIP-1429N|sgd:YCR020C-A(identity)	intact:EBI-745305(isoform-parent)|ensembl:ENSG00000185811(gene)|ensembl:ENST00000359197(transcript)|ensembl:ENST00000439701(transcript)|uniprotkb:Q13422-7(isoform-parent)|entrezgene/locuslink:10320(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:VUwG0xxj0NeyZKANRYCAgJGuqs8559292	rogid:ou/ovXYoMneBNVp4pj38VxenfyY9606	intact-crc:354D28928CCBB4A0|rigid:VoFNN/v7hsuD62HSV31gHLpXIy8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P23059	uniprotkb:Q9UFD9	intact:EBI-10950|ensemblfungi:YCR020C-A|uniprotkb:D6VR29	intact:EBI-10182375|uniprotkb:Q9UFQ5|uniprotkb:Q8IYP7|uniprotkb:Q9BY94|intact:EBI-28984856|ensembl:ENSP00000483386	psi-mi:naa38_yeast(display_long)|uniprotkb:MAK31(gene name)|psi-mi:MAK31(display_short)|uniprotkb:YCR020C-A(locus name)|uniprotkb:YCR20C-A(orf name)|uniprotkb:L-A virus GAG protein N-acetyltransferase subunit MAK31(gene name synonym)|uniprotkb:Maintenance of killer protein 31(gene name synonym)|uniprotkb:NAA38(gene name synonym)|uniprotkb:N-terminal acetyltransferase C complex subunit MAK31(gene name synonym)	psi-mi:rim3a_human(display_long)|uniprotkb:RIMBP3(gene name)|psi-mi:RIMBP3(display_short)|uniprotkb:KIAA1666(gene name synonym)|uniprotkb:RIMBP3A(gene name synonym)|uniprotkb:RIMS-binding protein 3.1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11524050|imex:IM-24995-183	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YCR020C-A(gene)|ensemblfungi:YCR020C-A_mRNA(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005688"(U6 snRNP)|go:"GO:0005829"(cytosol)|go:"GO:0006474"(N-terminal protein amino acid acetylation)|go:"GO:0016070"(RNA metabolic process)|go:"GO:0031417"(NatC complex)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071011"(precatalytic spliceosome)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR034110|rcsb pdb:6YGA|rcsb pdb:6YGB|rcsb pdb:6YGC|rcsb pdb:6YGD|refseq:NP_009948.1|sgd:S000000614|mint:P23059|dip:DIP-1429N|sgd:YCR020C-A(identity)	refseq:NP_056487.1|ensembl:ENSP00000483386|ensembl:ENSG00000275793(gene)|ensembl:ENST00000619918(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007286"(spermatid development)|go:"GO:0009566"(fertilization)|go:"GO:0030156"(benzodiazepine receptor binding)|go:"GO:0045202"(synapse)|interpro:IPR001452(Src homology-3)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR035515|interpro:IPR036028|interpro:IPR036116|interpro:IPR040325|rcsb pdb:2EGE|entrezgene/locuslink:85376(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:VUwG0xxj0NeyZKANRYCAgJGuqs8559292	rogid:iw34Gee4nqAH3pqUfCgQ6Jj++AA9606	intact-crc:90ED102DAFDB45A0|rigid:zNTOeTjSl+BVSEzL3VF/E9J4h2o	false	-	sufficient binding region:838-1639	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q5JR59-3	uniprotkb:P23293	intact:EBI-11522433|ensembl:ENSP00000370186	intact:EBI-17078|ensemblfungi:YPR161C|uniprotkb:D6W4G2	psi-mi:q5jr59-3(display_long)|uniprotkb:MTUS2(gene name)|psi-mi:MTUS2(display_short)|uniprotkb:CAZIP(gene name synonym)|uniprotkb:Cardiac zipper protein(gene name synonym)|uniprotkb:KIAA0774(gene name synonym)|uniprotkb:Microtubule plus-end tracking protein TIP150(gene name synonym)|uniprotkb:TIP150(gene name synonym)	psi-mi:bur1_yeast(display_long)|uniprotkb:SGV1(gene name)|psi-mi:SGV1(display_short)|uniprotkb:BUR1(gene name synonym)|uniprotkb:YPR161C(locus name)|uniprotkb:P9584.8(orf name)|uniprotkb:Bypass UAS requirement protein 1(gene name synonym)|uniprotkb:Suppressor of GPA1-Vall50 mutation protein 1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11524119|imex:IM-24995-190	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000132938(gene)|ensembl:ENST00000380808(transcript)|intact:EBI-742948(isoform-parent)|uniprotkb:Q5JR59-3(isoform-parent)|entrezgene/locuslink:23281(identity)	interpro:IPR011009(Protein kinase-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-SCE-674695|reactome:R-SCE-6796648|reactome:R-SCE-6807505|reactome:R-SCE-75955|reactome:R-SCE-9018519|refseq:NP_015487.1|sgd:S000006365|ensemblfungi:YPR161C(gene)|ensemblfungi:YPR161C_mRNA(transcript)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0030332"(cyclin binding)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|dip:DIP-5916N|mint:P23293|sgd:YPR161C(identity)	-	isoform-comment:No experimental confirmation available.	crc64:CC9034A4B10A510E	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:npId9tC7VoLN/jteoBiRbSYChPs9606	rogid:yPWc2VNSXjSxoSgzeiu7Jy5S1C0559292	intact-crc:788AB7A18A3F48EC|rigid:/q/RGhuOXkmYRC6xFcgGn2RsXgQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P23293	uniprotkb:Q08379	intact:EBI-17078|ensemblfungi:YPR161C|uniprotkb:D6W4G2	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	psi-mi:bur1_yeast(display_long)|uniprotkb:SGV1(gene name)|psi-mi:SGV1(display_short)|uniprotkb:BUR1(gene name synonym)|uniprotkb:YPR161C(locus name)|uniprotkb:P9584.8(orf name)|uniprotkb:Bypass UAS requirement protein 1(gene name synonym)|uniprotkb:Suppressor of GPA1-Vall50 mutation protein 1(gene name synonym)	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11524108|imex:IM-24995-189	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR011009(Protein kinase-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-SCE-674695|reactome:R-SCE-6796648|reactome:R-SCE-6807505|reactome:R-SCE-75955|reactome:R-SCE-9018519|refseq:NP_015487.1|sgd:S000006365|ensemblfungi:YPR161C(gene)|ensemblfungi:YPR161C_mRNA(transcript)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0030332"(cyclin binding)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|dip:DIP-5916N|mint:P23293|sgd:YPR161C(identity)	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N|entrezgene/locuslink:2801(identity)	-	crc64:CC9034A4B10A510E	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2017/05/26	rogid:yPWc2VNSXjSxoSgzeiu7Jy5S1C0559292	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	intact-crc:5DE97ABB7198D3FF|rigid:c8aT+hdlQkCrd4qPTq7qtHXpwp4	false	-	sufficient binding region:383-1002	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P23180	uniprotkb:Q9BYV6-2	intact:EBI-24332|uniprotkb:D3DKP4|ensemblfungi:YHL021C	intact:EBI-11522718|ensembl:ENSP00000297348	psi-mi:aim17_yeast(display_long)|uniprotkb:AIM17(gene name)|psi-mi:AIM17(display_short)|uniprotkb:FMP12(gene name synonym)|uniprotkb:Altered inheritance of mitochondria protein 17, mitochondrial(gene name synonym)|uniprotkb:Found in mitochondrial proteome protein 12(gene name synonym)|uniprotkb:YHL021C(locus name)	psi-mi:q9byv6-2(display_long)|uniprotkb:TRIM55(gene name)|psi-mi:TRIM55(display_short)|uniprotkb:MURF2(gene name synonym)|uniprotkb:Muscle-specific RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 29(gene name synonym)|uniprotkb:RNF29(gene name synonym)|uniprotkb:p50(isoform synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11524081|imex:IM-24995-186	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011842.1|sgd:S000001013|reactome:R-SCE-71262|dip:DIP-4919N|ensemblfungi:YHL021C(gene)|ensemblfungi:YHL021C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0045329"(carnitine biosynthetic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0051213"(dioxygenase activity)|interpro:IPR003819(Taurine catabolism dioxygenase TauD/TfdA)|interpro:IPR042098|sgd:YHL021C(identity)	intact:EBI-2341179(isoform-parent)|uniprotkb:Q9BYV6-2(isoform-parent)|ensembl:ENSG00000147573(gene)|ensembl:ENST00000353317(transcript)|entrezgene/locuslink:84675(identity)	-	crc64:568B17051DB60899	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:EckG7oFiGF7UJou9Cu2fZCGiUKE559292	rogid:9t8UhK+Z1yBqjnQrOqPD76NuXGg9606	intact-crc:0E37BBA8B188E4C2|rigid:r5UIlR4ULSzRqRpAZyIMdIwM8e8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P46379-2	uniprotkb:P23285	intact:EBI-10988864|ensembl:ENSP00000211379|ensembl:ENSP00000365143|ensembl:ENSP00000372938|ensembl:ENSP00000372940|ensembl:ENSP00000389121|ensembl:ENSP00000410156|ensembl:ENSP00000412110|ensembl:ENSP00000413698	intact:EBI-5448|uniprotkb:D3DL06|ensemblfungi:YHR057C	psi-mi:p46379-2(display_long)|uniprotkb:BAG6(gene name)|psi-mi:BAG6(display_short)|uniprotkb:BAG family molecular chaperone regulator 6(gene name synonym)|uniprotkb:BAT3(gene name synonym)|uniprotkb:BCL2-associated athanogene 6(gene name synonym)|uniprotkb:G3(gene name synonym)|uniprotkb:HLA-B-associated transcript 3(gene name synonym)|uniprotkb:Protein G3(gene name synonym)|uniprotkb:Protein Scythe(gene name synonym)	psi-mi:cypb_yeast(display_long)|uniprotkb:CYP2(gene name synonym)|uniprotkb:YHR057C(locus name)|uniprotkb:CPR2(gene name)|psi-mi:CPR2(display_short)|uniprotkb:CRG(gene name synonym)|uniprotkb:SCC2(gene name synonym)|uniprotkb:Cyclophilin B(gene name synonym)|uniprotkb:Cyclophilin-related protein(gene name synonym)|uniprotkb:Rotamase B(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11524090|imex:IM-24995-187	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-347552(isoform-parent)|uniprotkb:P46379-2(isoform-parent)|ensembl:ENSG00000096155(gene)|ensembl:ENSG00000204463(gene)|ensembl:ENSG00000229524(gene)|ensembl:ENSG00000233348(gene)|ensembl:ENST00000211379(transcript)|ensembl:ENST00000375976(transcript)|ensembl:ENST00000383446(transcript)|ensembl:ENST00000383448(transcript)|ensembl:ENST00000417144(transcript)|ensembl:ENST00000419847(transcript)|ensembl:ENST00000442479(transcript)|ensembl:ENST00000443182(transcript)|entrezgene/locuslink:7917(identity)	refseq:NP_011924.1|sgd:S000001099|dip:DIP-1280N|ensemblfungi:YHR057C(gene)|ensemblfungi:YHR057C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006457"(protein folding)|go:"GO:0016018"(cyclosporin A binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|interpro:IPR020892|interpro:IPR024936|interpro:IPR029000|sgd:YHR057C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:7y9hxqfcTmnCBRON6qNoHPCdODY9606	rogid:jKSwBj1KpYZTRNaWOrKxCwC0rAY559292	intact-crc:7096C5C9DBD1FFA6|rigid:GJevR6h5GvKTdi1t8sJsrw+dIgE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9Y2W7	uniprotkb:P23285	intact:EBI-751501|uniprotkb:Q53TJ5|uniprotkb:Q96T40|uniprotkb:Q9UJ84|uniprotkb:Q9UJ85|uniprotkb:Q3YAC3|uniprotkb:Q3YAC4|uniprotkb:H7BY46|ensembl:ENSP00000295225	intact:EBI-5448|uniprotkb:D3DL06|ensemblfungi:YHR057C	psi-mi:csen_human(display_long)|uniprotkb:Kv channel-interacting protein 3(gene name synonym)|uniprotkb:A-type potassium channel modulatory protein 3(gene name synonym)|uniprotkb:DRE-antagonist modulator(gene name synonym)|uniprotkb:KCNIP3(gene name)|psi-mi:KCNIP3(display_short)|uniprotkb:DREAM(gene name synonym)|uniprotkb:KCHIP3(gene name synonym)|uniprotkb:CSEN(gene name synonym)	psi-mi:cypb_yeast(display_long)|uniprotkb:CYP2(gene name synonym)|uniprotkb:YHR057C(locus name)|uniprotkb:CPR2(gene name)|psi-mi:CPR2(display_short)|uniprotkb:CRG(gene name synonym)|uniprotkb:SCC2(gene name synonym)|uniprotkb:Cyclophilin B(gene name synonym)|uniprotkb:Cyclophilin-related protein(gene name synonym)|uniprotkb:Rotamase B(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11524099|imex:IM-24995-188	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001030086.1|refseq:NP_038462.1|ensembl:ENSG00000115041(gene)|ensembl:ENST00000295225(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005244"(voltage-gated ion channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0030425"(dendrite)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0043679"(axon terminus)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:1901379"(regulation of potassium ion transmembrane transport)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR028846|rcsb pdb:2E6W|reactome:R-HSA-5576894|entrezgene/locuslink:30818(identity)	refseq:NP_011924.1|sgd:S000001099|dip:DIP-1280N|ensemblfungi:YHR057C(gene)|ensemblfungi:YHR057C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006457"(protein folding)|go:"GO:0016018"(cyclosporin A binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|interpro:IPR020892|interpro:IPR024936|interpro:IPR029000|sgd:YHR057C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Mqp4XdEur4uc6jY9dGsn8CHLE4w9606	rogid:jKSwBj1KpYZTRNaWOrKxCwC0rAY559292	intact-crc:3294C8924DE3E74A|rigid:aQbFCfB0uPIea3j+XVISVUl8XIw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P24280	uniprotkb:Q96DZ9-2	intact:EBI-16535|uniprotkb:D6VZQ3|ensemblfungi:YMR079W	intact:EBI-11522780|ensembl:ENSP00000352270|ensembl:ENSP00000497215	psi-mi:sec14_yeast(display_long)|uniprotkb:SEC14(gene name)|psi-mi:SEC14(display_short)|uniprotkb:Phosphatidylinositol/phosphatidylcholine transfer protein(gene name synonym)|uniprotkb:PIT1(gene name synonym)|uniprotkb:YM9582.04(orf name)|uniprotkb:YMR079W(locus name)	psi-mi:q96dz9-2(display_long)|uniprotkb:CMTM5(gene name)|psi-mi:CMTM5(display_short)|uniprotkb:CKLFSF5(gene name synonym)|uniprotkb:Chemokine-like factor superfamily member 5(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11524165|imex:IM-24995-195	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013796.1|sgd:S000004684|ensemblfungi:YMR079W(gene)|ensemblfungi:YMR079W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0008525"(phosphatidylcholine transporter activity)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0008526"(phosphatidylinositol transfer activity)|go:"GO:0015914"(phospholipid transport)|go:"GO:0030437"(ascospore formation)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0046488"(phosphatidylinositol metabolic process)|go:"GO:0048194"(Golgi vesicle budding)|go:"GO:1901352"(negative regulation of phosphatidylglycerol biosynthetic process)|go:"GO:2001246"(negative regulation of phosphatidylcholine biosynthetic process)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR011074(Phosphatidylinositol transfer protein-like, N-terminal)|interpro:IPR036273|interpro:IPR036865|rcsb pdb:1AUA|rcsb pdb:6F0E|dip:DIP-1610N|mint:P24280|sgd:YMR079W(identity)	ensembl:ENSG00000166091(gene)|ensembl:ENST00000359320(transcript)|ensembl:ENST00000649278(transcript)|intact:EBI-2548702(isoform-parent)|uniprotkb:Q96DZ9-2(isoform-parent)|entrezgene/locuslink:116173(identity)	-	crc64:CCB69404A8A0963B	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:6KY0fOn92xmZkZBq10NHRCWtd7w559292	rogid:2TJ7rZKQNb5hH5gz9i+ujOEOIOg9606	intact-crc:71B257F22440426E|rigid:L/SnJTuS/SdJO7xn0y/aL4LubYI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P24280	uniprotkb:Q6RW13-2	intact:EBI-16535|uniprotkb:D6VZQ3|ensemblfungi:YMR079W	intact:EBI-11522760|ensembl:ENSP00000365816	psi-mi:sec14_yeast(display_long)|uniprotkb:SEC14(gene name)|psi-mi:SEC14(display_short)|uniprotkb:Phosphatidylinositol/phosphatidylcholine transfer protein(gene name synonym)|uniprotkb:PIT1(gene name synonym)|uniprotkb:YM9582.04(orf name)|uniprotkb:YMR079W(locus name)	psi-mi:q6rw13-2(display_long)|uniprotkb:AGTRAP(gene name)|psi-mi:AGTRAP(display_short)|uniprotkb:AT1 receptor-associated protein(gene name synonym)|uniprotkb:ATRAP(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11524156|imex:IM-24995-194	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013796.1|sgd:S000004684|ensemblfungi:YMR079W(gene)|ensemblfungi:YMR079W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0008525"(phosphatidylcholine transporter activity)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0008526"(phosphatidylinositol transfer activity)|go:"GO:0015914"(phospholipid transport)|go:"GO:0030437"(ascospore formation)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0046488"(phosphatidylinositol metabolic process)|go:"GO:0048194"(Golgi vesicle budding)|go:"GO:1901352"(negative regulation of phosphatidylglycerol biosynthetic process)|go:"GO:2001246"(negative regulation of phosphatidylcholine biosynthetic process)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR011074(Phosphatidylinositol transfer protein-like, N-terminal)|interpro:IPR036273|interpro:IPR036865|rcsb pdb:1AUA|rcsb pdb:6F0E|dip:DIP-1610N|mint:P24280|sgd:YMR079W(identity)	ensembl:ENSG00000177674(gene)|ensembl:ENST00000376629(transcript)|intact:EBI-741181(isoform-parent)|uniprotkb:Q6RW13-2(isoform-parent)|entrezgene/locuslink:57085(identity)	-	crc64:CCB69404A8A0963B	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:6KY0fOn92xmZkZBq10NHRCWtd7w559292	rogid:PNzVis/8puQZBJ562gCqZKc078s9606	intact-crc:07C5F64A57391333|rigid:Om2ejsdhmZcM+TfO/PN828HwyqI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8N6L0	uniprotkb:P23968	intact:EBI-749265|uniprotkb:Q96MC3|ensembl:ENSP00000404220	intact:EBI-20293|uniprotkb:D3DKX3|ensemblfungi:YHR026W	psi-mi:kash5_human(display_long)|uniprotkb:KASH5(gene name)|psi-mi:KASH5(display_short)|uniprotkb:CCDC155(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 155(gene name synonym)|uniprotkb:KASH domain-containing protein 5(gene name synonym)	psi-mi:vato_yeast(display_long)|uniprotkb:VMA16(gene name)|psi-mi:VMA16(display_short)|uniprotkb:PPA1(gene name synonym)|uniprotkb:YHR026W(locus name)|uniprotkb:Vacuolar proton pump c'' subunit(gene name synonym)|uniprotkb:V-ATPase 22 kDa proteolipid subunit(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11524128|imex:IM-24995-191	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_653289.3|ensembl:ENSG00000161609(gene)|ensembl:ENST00000447857(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034397"(telomere localization)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051225"(spindle assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0090172"(microtubule cytoskeleton organization involved in homologous chromosome segregation)|go:"GO:0090220"(chromosome localization to nuclear envelope involved in homologous chromosome segregation)|go:"GO:0090619"(meiotic spindle pole)|interpro:IPR011992(EF-Hand type)|interpro:IPR028168|interpro:IPR028170|interpro:IPR039508|mint:Q8N6L0|rcsb pdb:6R2I|rcsb pdb:6WMF|entrezgene/locuslink:147872(identity)	refseq:NP_011891.1|sgd:S000001068|rcsb pdb:6O7W|rcsb pdb:6O7X|rcsb pdb:6PE4|rcsb pdb:6PE5|reactome:R-SCE-1222556|reactome:R-SCE-77387|reactome:R-SCE-917977|reactome:R-SCE-9639288|ensemblfungi:YHR026W(gene)|ensemblfungi:YHR026W_mRNA(transcript)|go:"GO:0000220"(vacuolar proton-transporting V-type ATPase, V0 domain)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0008553"(P-type proton-exporting transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016471"(vacuolar proton-transporting V-type ATPase complex)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR000245(ATPase, V0 complex, proteolipid subunit C,)|interpro:IPR002379(ATPase, F0/V0 complex, subunit C)|interpro:IPR035921|rcsb pdb:5TJ5|rcsb pdb:5VOX|rcsb pdb:5VOY|rcsb pdb:5VOZ|rcsb pdb:6C6L|rcsb pdb:6M0R|rcsb pdb:6M0S|rcsb pdb:6O7T|rcsb pdb:6O7U|rcsb pdb:6O7V|dip:DIP-4054N|mint:P23968|sgd:YHR026W(identity)	-	-	crc64:033FF5A516B97F8B	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Wl9L7AcvDHCZuKjYLn8QgGIbZTc9606	rogid:pQMMMGsUAtBoa6IF8yVU2t+odQQ559292	intact-crc:8892D508BE638A89|rigid:6kULBrDc7RKOSwU40SNKrsukouQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96BA8	uniprotkb:P23968	intact:EBI-6942903|ensembl:ENSP00000481956|intact:MINT-268046|intact:MINT-8162577|uniprotkb:Q8N2D5|uniprotkb:Q96CP0	intact:EBI-20293|uniprotkb:D3DKX3|ensemblfungi:YHR026W	psi-mi:cr3l1_human(display_long)|uniprotkb:CREB3L1(gene name)|psi-mi:CREB3L1(display_short)|uniprotkb:OASIS(gene name synonym)|uniprotkb:PSEC0238(orf name)|uniprotkb:Old astrocyte specifically-induced substance(gene name synonym)	psi-mi:vato_yeast(display_long)|uniprotkb:VMA16(gene name)|psi-mi:VMA16(display_short)|uniprotkb:PPA1(gene name synonym)|uniprotkb:YHR026W(locus name)|uniprotkb:Vacuolar proton pump c'' subunit(gene name synonym)|uniprotkb:V-ATPase 22 kDa proteolipid subunit(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11524137|imex:IM-24995-192	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157613(gene)|ensembl:ENST00000621158(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0070278"(extracellular matrix constituent secretion)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029805|mint:Q96BA8|reactome:R-HSA-8874211|refseq:NP_443086.1|entrezgene/locuslink:90993(identity)	refseq:NP_011891.1|sgd:S000001068|rcsb pdb:6O7W|rcsb pdb:6O7X|rcsb pdb:6PE4|rcsb pdb:6PE5|reactome:R-SCE-1222556|reactome:R-SCE-77387|reactome:R-SCE-917977|reactome:R-SCE-9639288|ensemblfungi:YHR026W(gene)|ensemblfungi:YHR026W_mRNA(transcript)|go:"GO:0000220"(vacuolar proton-transporting V-type ATPase, V0 domain)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0008553"(P-type proton-exporting transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016471"(vacuolar proton-transporting V-type ATPase complex)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR000245(ATPase, V0 complex, proteolipid subunit C,)|interpro:IPR002379(ATPase, F0/V0 complex, subunit C)|interpro:IPR035921|rcsb pdb:5TJ5|rcsb pdb:5VOX|rcsb pdb:5VOY|rcsb pdb:5VOZ|rcsb pdb:6C6L|rcsb pdb:6M0R|rcsb pdb:6M0S|rcsb pdb:6O7T|rcsb pdb:6O7U|rcsb pdb:6O7V|dip:DIP-4054N|mint:P23968|sgd:YHR026W(identity)	-	comment:mint|function:"Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE"	crc64:033FF5A516B97F8B	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:sMWUFmBeBBCO+T0Y2CuB/un1lBg9606	rogid:pQMMMGsUAtBoa6IF8yVU2t+odQQ559292	intact-crc:4E6A5262DDDD00B9|rigid:yZXLin542GrbPE4nOM51K4bgRXA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P24279	uniprotkb:Q9BTE3-2	intact:EBI-10541|ensemblfungi:YEL032W|uniprotkb:D3DLL7	intact:EBI-9384556|ensembl:ENSP00000358073	psi-mi:mcm3_yeast(display_long)|uniprotkb:MCM3(gene name)|psi-mi:MCM3(display_short)|uniprotkb:YEL032W(locus name)|uniprotkb:SYGP-ORF23(orf name)|uniprotkb:Minichromosome maintenance protein 3(gene name synonym)	psi-mi:q9bte3-2(display_long)|uniprotkb:MCMBP(gene name)|psi-mi:MCMBP(display_short)|uniprotkb:C10orf119(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11524147|imex:IM-24995-193	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010882.1|sgd:S000000758|go:"GO:0005524"(ATP binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006348"|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0042555"(MCM complex)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902975"(mitotic DNA replication initiation)|go:"GO:1904931"(MCM complex binding)|interpro:IPR001208(MCM)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR008046(MCM protein 3)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|rcsb pdb:3JA8|rcsb pdb:3JC5|rcsb pdb:3JC6|rcsb pdb:3JC7|rcsb pdb:5BK4|rcsb pdb:5U8S|rcsb pdb:5U8T|rcsb pdb:5V8F|rcsb pdb:6EYC|rcsb pdb:6F0L|rcsb pdb:6HV9|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6RQC|rcsb pdb:6SKL|rcsb pdb:6SKO|rcsb pdb:6U0M|rcsb pdb:6WGC|rcsb pdb:6WGF|rcsb pdb:6WGG|rcsb pdb:6WGI|reactome:R-SCE-68949|reactome:R-SCE-68962|reactome:R-SCE-69052|rcsb pdb:5XF8|ensemblfungi:YEL032W(gene)|ensemblfungi:YEL032W_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|mint:P24279|dip:DIP-2407N|sgd:YEL032W(identity)	intact:EBI-749378(isoform-parent)|uniprotkb:Q9BTE3-2(isoform-parent)|ensembl:ENSG00000197771(gene)|ensembl:ENST00000369077(transcript)|entrezgene/locuslink:79892(identity)	-	crc64:43DD4DACAF4456DC	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:OsFbdaTeE1vPQObriGt5M6mTPzk559292	rogid:nJOq6jis1maK+M/X0TcR44HlxRw9606	intact-crc:A0FA09ABA0656087|rigid:vu2Hl8RYLaSrtUaj8zIr7gqfUhw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9HD26-2	uniprotkb:P25299	intact:EBI-11102276|ensembl:ENSP00000052569	intact:EBI-15640|uniprotkb:D6VU95|ensemblfungi:YGL044C	psi-mi:q9hd26-2(display_long)|uniprotkb:GOPC(gene name)|psi-mi:GOPC(display_short)|uniprotkb:CAL(gene name synonym)|uniprotkb:CFTR-associated ligand(gene name synonym)|uniprotkb:FIG(gene name synonym)|uniprotkb:Fused in glioblastoma(gene name synonym)|uniprotkb:PDZ protein interacting specifically with TC10(gene name synonym)	psi-mi:rna15_yeast(display_long)|uniprotkb:YGL044C(locus name)|uniprotkb:RNA15(gene name)|psi-mi:RNA15(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11524198|imex:IM-24995-198	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000047932(gene)|ensembl:ENST00000052569(transcript)|intact:EBI-349832(isoform-parent)|uniprotkb:Q9HD26-2(isoform-parent)|entrezgene/locuslink:57120(identity)	refseq:NP_011471.1|sgd:S000003012|ensemblfungi:YGL044C(gene)|ensemblfungi:YGL044C_mRNA(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0005849"(mRNA cleavage factor complex)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0072423"(response to DNA damage checkpoint signaling)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR026896|interpro:IPR035979|interpro:IPR038192|rcsb pdb:2KM8|rcsb pdb:2L9B|rcsb pdb:2X1A|rcsb pdb:2X1B|rcsb pdb:2X1F|dip:DIP-1489N|mint:P25299|sgd:YGL044C(identity)	-	-	crc64:10053B8648A71ECB	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:QoEGY54FfmwTrpGVMQN9ASGPgVI9606	rogid:TqfxsTHAh9CPJJ6Q7uH6kz988hk559292	intact-crc:5750910DE7DA11D4|rigid:uWGqexURRYxTTx+kiSeq1kdSbkc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P25299	uniprotkb:Q7Z3B4	intact:EBI-15640|uniprotkb:D6VU95|ensemblfungi:YGL044C	intact:EBI-741048|uniprotkb:Q96EA7|uniprotkb:Q9NVL5|uniprotkb:Q9P0I1|uniprotkb:B2RCK7|intact:EBI-10966427|uniprotkb:B4DT35|ensembl:ENSP00000264883	psi-mi:rna15_yeast(display_long)|uniprotkb:YGL044C(locus name)|uniprotkb:RNA15(gene name)|psi-mi:RNA15(display_short)	psi-mi:nup54_human(display_long)|uniprotkb:54 kDa nucleoporin(gene name synonym)|uniprotkb:NUP54(gene name)|psi-mi:NUP54(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11524187|imex:IM-24995-197	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011471.1|sgd:S000003012|ensemblfungi:YGL044C(gene)|ensemblfungi:YGL044C_mRNA(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0005849"(mRNA cleavage factor complex)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0072423"(response to DNA damage checkpoint signaling)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR026896|interpro:IPR035979|interpro:IPR038192|rcsb pdb:2KM8|rcsb pdb:2L9B|rcsb pdb:2X1A|rcsb pdb:2X1B|rcsb pdb:2X1F|dip:DIP-1489N|mint:P25299|sgd:YGL044C(identity)	refseq:NP_059122.2|refseq:NP_001265532.1|ensembl:ENSG00000138750(gene)|ensembl:ENST00000264883(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0006605"(protein targeting)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036228"(protein localization to nuclear inner membrane)|go:"GO:0042306"(regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051028"(mRNA transport)|interpro:IPR024864|interpro:IPR025712|interpro:IPR040985|mint:Q7Z3B4|rcsb pdb:4JNU|rcsb pdb:4JNV|rcsb pdb:4JO7|rcsb pdb:4JO9|rcsb pdb:5IJN|rcsb pdb:5IJO|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|entrezgene/locuslink:53371(identity)	-	crc64:10053B8648A71ECB	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:TqfxsTHAh9CPJJ6Q7uH6kz988hk559292	rogid:/X2b8J20uRh86bEeCc1tJSRuaIM9606	intact-crc:D02D4F581CF43CEA|rigid:DPrDjqDiTFRoLirTjKgYNRaYX3Q	false	-	sufficient binding region:1-493	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UJ83	uniprotkb:P25299	intact:EBI-746580|uniprotkb:Q9BV42|uniprotkb:Q9P0A2|ensembl:ENSP00000323811|uniprotkb:E9PEN4|uniprotkb:B4DWI1|uniprotkb:B4DXI5	intact:EBI-15640|uniprotkb:D6VU95|ensemblfungi:YGL044C	psi-mi:hacl1_human(display_long)|uniprotkb:2-hydroxyphytanoyl-CoA lyase(gene name synonym)|uniprotkb:Phytanoyl-CoA 2-hydroxylase 2(gene name synonym)|uniprotkb:HACL1(gene name)|psi-mi:HACL1(display_short)|uniprotkb:HPCL2(gene name synonym)|uniprotkb:HSPC279(orf name)|uniprotkb:HPCL(gene name synonym)|uniprotkb:PHYH2(gene name synonym)	psi-mi:rna15_yeast(display_long)|uniprotkb:YGL044C(locus name)|uniprotkb:RNA15(gene name)|psi-mi:RNA15(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11524207|imex:IM-24995-199	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001271344.1|refseq:NP_036392.2|ensembl:ENSG00000131373(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005777"(peroxisome)|ensembl:ENST00000321169(transcript)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006625"(protein targeting to peroxisome)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0016830"(carbon-carbon lyase activity)|go:"GO:0030976"(thiamine pyrophosphate binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0097089"(methyl-branched fatty acid metabolic process)|go:"GO:0106360"(2-hydroxy-3-methylhexadecanoyl-CoA lyase activity)|go:"GO:0106376"(2-hydroxyphytanoyl-CoA lyase activity)|go:"GO:1903512"(phytanic acid metabolic process)|interpro:IPR011766(Thiamine pyrophosphate enzyme, C-terminal TPP-binding)|interpro:IPR012000(Thiamine pyrophosphate enzyme, central region)|interpro:IPR012001(Thiamine pyrophosphate enzyme, N-terminal TPP binding region)|interpro:IPR029035|interpro:IPR029061|reactome:R-HSA-389599|reactome:R-HSA-9033241|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001561"(fatty acid alpha-oxidation)|refseq:NP_001271342.1|refseq:NP_001271345.1|entrezgene/locuslink:26061(identity)	refseq:NP_011471.1|sgd:S000003012|ensemblfungi:YGL044C(gene)|ensemblfungi:YGL044C_mRNA(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0005849"(mRNA cleavage factor complex)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0072423"(response to DNA damage checkpoint signaling)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR026896|interpro:IPR035979|interpro:IPR038192|rcsb pdb:2KM8|rcsb pdb:2L9B|rcsb pdb:2X1A|rcsb pdb:2X1B|rcsb pdb:2X1F|dip:DIP-1489N|mint:P25299|sgd:YGL044C(identity)	-	-	crc64:10053B8648A71ECB	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:030QpE5/e+3ZEuyUaK+RM3w8x4A9606	rogid:TqfxsTHAh9CPJJ6Q7uH6kz988hk559292	intact-crc:01BDEBE8833A429F|rigid:Ufyq0B2HZmr8lq+Ii+gGlqTRJ1E	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P25337	uniprotkb:Q9BW62	intact:EBI-547|ensemblfungi:YCR063W|uniprotkb:D6VR67	intact:EBI-743591|uniprotkb:A8K5X4|ensembl:ENSP00000369989|ensembl:ENSP00000369991	psi-mi:bud31_yeast(display_long)|uniprotkb:BUD31(gene name)|psi-mi:BUD31(display_short)|uniprotkb:Bud site selection protein 31(gene name synonym)|uniprotkb:CWC14(gene name synonym)|uniprotkb:Complexed with CEF1 protein 14(gene name synonym)|uniprotkb:YCR63W(orf name)|uniprotkb:YCR903(orf name)|uniprotkb:YCR063W(locus name)	psi-mi:katl1_human(display_long)|uniprotkb:p60 katanin-like 1(gene name synonym)|uniprotkb:KATNAL1(gene name)|psi-mi:KATNAL1(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11524225|imex:IM-24995-201	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009990.1|sgd:S000000659|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005686"(U2 snRNP)|interpro:IPR001748(G10 protein)|interpro:IPR018230|rcsb pdb:2MY1|ensemblfungi:YCR063W(gene)|ensemblfungi:YCR063W_mRNA(transcript)|go:"GO:0000282"(cellular bud site selection)|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|dip:DIP-1180N|mint:P25337|sgd:YCR063W(identity)	refseq:NP_001014402.1|refseq:NP_115492.1|refseq:XP_005266631.1|ensembl:ENSG00000102781(gene)|ensembl:ENST00000380615(transcript)|ensembl:ENST00000380617(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005874"(microtubule)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008017"(microtubule binding)|go:"GO:0008568"(microtubule-severing ATPase activity)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016853"(isomerase activity)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0042802"(identical protein binding)|go:"GO:0051013"(microtubule severing)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR027417|interpro:IPR028594|interpro:IPR028596|interpro:IPR041569|rcsb pdb:6B5C|entrezgene/locuslink:84056(identity)	-	crc64:70A8B15F8DA6F85D	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:DImrf7jgUrSuQtfiOvBeJr5Cl/w559292	rogid:Usi4KXsvZnNfMOGuWVSz4mfrTaE9606	intact-crc:2C156945B8A32596|rigid:gvpInP+Nf6YG6/dZY+d6nRz8z3k	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O15217	uniprotkb:P25335	intact:EBI-752440|uniprotkb:Q5T7Q8|uniprotkb:Q9BX18|uniprotkb:Q9H414|uniprotkb:B2RD15|uniprotkb:Q6P4G1|ensembl:ENSP00000359998|ensembl:ENSP00000360002	intact:EBI-2442|uniprotkb:D6VVW0|ensemblfungi:YIR029W	psi-mi:gsta4_human(display_long)|uniprotkb:Glutathione S-transferase A4-4(gene name synonym)|uniprotkb:GST class-alpha member 4(gene name synonym)|uniprotkb:GSTA4(gene name)|psi-mi:GSTA4(display_short)	psi-mi:allc_yeast(display_long)|uniprotkb:DAL2(gene name)|psi-mi:DAL2(display_short)|uniprotkb:ALC1(gene name synonym)|uniprotkb:Allantoate amidinohydrolase(gene name synonym)|uniprotkb:YIR029W(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11524216|imex:IM-24995-200	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001503.1|refseq:XP_005249092.1|ensembl:ENSG00000170899(gene)|ensembl:ENST00000370959(transcript)|ensembl:ENST00000370963(transcript)|go:"GO:0004364"(glutathione transferase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0006805"(xenobiotic metabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|interpro:IPR003080(Glutathione S-transferase, alpha class)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR036249|interpro:IPR036282|interpro:IPR040079|rcsb pdb:1GUL|rcsb pdb:1GUM|rcsb pdb:3IK7|reactome:R-HSA-156590|entrezgene/locuslink:2941(identity)	refseq:NP_012295.1|sgd:S000001468|interpro:IPR005164(Allantoicase)|interpro:IPR015908(Allantoicase region)|interpro:IPR008979(Galactose-binding like)|rcsb pdb:1O59|rcsb pdb:1SG3|ensemblfungi:YIR029W(gene)|ensemblfungi:YIR029W_mRNA(transcript)|go:"GO:0000256"(allantoin catabolic process)|go:"GO:0004037"(allantoicase activity)|go:"GO:0006144"(purine nucleobase metabolic process)|sgd:YIR029W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:9yVcqmJL64S0kxOW5RJWbOJ25bo9606	rogid:N4TpitQzuAZuemg9Jk458EUQUWc559292	intact-crc:DD95BF3305014445|rigid:HcrN/v7EspNcIkRwbk4OjqYnRgk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9H972-2	uniprotkb:P25044	intact:EBI-11524174|ensembl:ENSP00000341353	intact:EBI-14183|ensemblfungi:YDL230W|uniprotkb:D6VRC6	psi-mi:q9h972-2(display_long)|uniprotkb:C14orf93(gene name)|psi-mi:C14orf93(display_short)	psi-mi:ptp1_yeast(display_long)|uniprotkb:Protein-tyrosine phosphatase 1(gene name synonym)|uniprotkb:PTP1(gene name)|psi-mi:PTP1(display_short)|uniprotkb:YDL230W(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11524178|imex:IM-24995-196	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-10329620(isoform-parent)|ensembl:ENSG00000100802(gene)|ensembl:ENST00000341470(transcript)|uniprotkb:Q9H972-2(isoform-parent)|entrezgene/locuslink:60686(identity)	refseq:NP_010051.1|sgd:S000002389|ensemblfungi:YDL230W(gene)|ensemblfungi:YDL230W_mRNA(transcript)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007124"(pseudohyphal growth)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR016277(Non-receptor tyrosine-protein phosphatase type 1, yeast)|interpro:IPR029021|go:"GO:0005737"(cytoplasm)|dip:DIP-2765N|reactome:R-SCE-6798695|sgd:YDL230W(identity)	-	isoform-comment:No experimental confirmation available.	crc64:15F71E50694BE562	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:78CwgvNc8HhvQM4urISJ8VU88BU9606	rogid:uQd7Homoz5Z834hLaSgQssol+EE559292	intact-crc:FA9F9B2BF9358C07|rigid:BlfdJ2WU+yBQv0fitvOxz4ATEXg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q969F0	uniprotkb:P25353	intact:EBI-743099|ensembl:ENSP00000359375	intact:EBI-3691762|uniprotkb:D6VR36|uniprotkb:Q8NIL9|ensemblfungi:YCR026C	psi-mi:fate1_human(display_long)|uniprotkb:Tumor antigen BJ-HCC-2(gene name synonym)|uniprotkb:Cancer/testis antigen 43(gene name synonym)|uniprotkb:FATE1(gene name)|psi-mi:FATE1(display_short)|uniprotkb:FATE(gene name synonym)	psi-mi:npp1_yeast(display_long)|uniprotkb:NPP1(gene name)|psi-mi:NPP1(display_short)|uniprotkb:YCR26C(orf name)|uniprotkb:YCR246(orf name)|uniprotkb:YCR026C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11524272|imex:IM-24995-206	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_149076.1|ensembl:ENSG00000147378(gene)|ensembl:ENST00000370350(transcript)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|go:"GO:0051562"(negative regulation of mitochondrial calcium ion concentration)|interpro:IPR039153|interpro:IPR039433|mint:Q969F0|entrezgene/locuslink:89885(identity)	refseq:NP_009955.2|sgd:S000000621|interpro:IPR017850(Alkaline-phosphatase-like, core domain)|interpro:IPR002591(Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase)|reactome:R-SCE-1660662|reactome:R-SCE-6814848|ensemblfungi:YCR026C(gene)|ensemblfungi:YCR026C_mRNA(transcript)|go:"GO:0004528"(phosphodiesterase I activity)|go:"GO:0009141"(nucleoside triphosphate metabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016036"(cellular response to phosphate starvation)|go:"GO:0017111"(nucleoside-triphosphatase activity)|go:"GO:0035529"(NADH pyrophosphatase activity)|go:"GO:0036218"(dTTP diphosphatase activity)|go:"GO:0047429"(nucleoside-triphosphate diphosphatase activity)|reactome:R-SCE-196843|reactome:R-SCE-6798695|sgd:YCR026C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Nm1N6lO92MHr5rIKC007oouF5RE9606	rogid:eudbgXN3Y6QR2ebTYl+l1JoNuG0559292	intact-crc:CBB729E3EEC3E951|rigid:iOSqFRP5udaWXmqwEmtaFlHj9jM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9H9H4	uniprotkb:P25343	intact:EBI-4400866|intact:EBI-28975719|ensembl:ENSP00000267202	intact:EBI-14490|uniprotkb:D6VR18|ensemblfungi:YCR009C	psi-mi:vp37b_human(display_long)|uniprotkb:VPS37B(gene name)|psi-mi:VPS37B(display_short)|uniprotkb:ESCRT-I complex subunit VPS37B(gene name synonym)	psi-mi:rv161_yeast(display_long)|uniprotkb:RVS161(gene name)|psi-mi:RVS161(display_short)|uniprotkb:END6(gene name synonym)|uniprotkb:SPE161(gene name synonym)|uniprotkb:YCR009C(locus name)|uniprotkb:YCR9C(orf name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11524263|imex:IM-24995-205	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000267202|refseq:NP_078943.1|ensembl:ENSG00000139722(gene)|ensembl:ENST00000267202(transcript)|go:"GO:0000813"(ESCRT I complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0010008"(endosome membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0030496"(midbody)|go:"GO:0031902"(late endosome membrane)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1902188"(obsolete positive regulation of viral release from host cell)|go:"GO:1903774"(positive regulation of viral budding via host ESCRT complex)|interpro:IPR009851(Modifier of rudimentary, Modr)|interpro:IPR029012|interpro:IPR037202|mint:Q9H9H4|rcsb pdb:6VME|reactome:R-HSA-162588|reactome:R-HSA-174490|reactome:R-HSA-917729|reactome:R-HSA-9610379|reactome:R-HSA-9615710|entrezgene/locuslink:79720(identity)	ensemblfungi:YCR009C(gene)|ensemblfungi:YCR009C_mRNA(transcript)|go:"GO:0000747"(conjugation with cellular fusion)|go:"GO:0005829"(cytosol)|go:"GO:0005937"(mating projection)|go:"GO:0006897"(endocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030479"(actin cortical patch)|go:"GO:0031097"(medial cortex)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0042594"(response to starvation)|go:"GO:0043332"(mating projection tip)|go:"GO:0045121"(membrane raft)|go:"GO:0051666"(actin cortical patch localization)|go:"GO:0060988"(lipid tube assembly)|go:"GO:0097320"(plasma membrane tubulation)|go:"GO:1990528"(Rvs161p-Rvs167p complex)|interpro:IPR004148(BAR)|interpro:IPR027267|go:"GO:0006970"(response to osmotic stress)|interpro:IPR037429|refseq:NP_009935.1|sgd:S000000602|mint:P25343|dip:DIP-1601N|sgd:YCR009C(identity)	-	-	crc64:B35EA00E0C900E2D	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:dj398+zsegXf+gk9OiSeZAVlmqk9606	rogid:IdjO8RS5vcYMeGxuoPoa/5e7QJQ559292	intact-crc:973682E89AF5AFFE|rigid:pgwHh6rLZ+gz+I8+RrqpD7S9KyI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P25343	uniprotkb:O15156-2	intact:EBI-14490|uniprotkb:D6VR18|ensemblfungi:YCR009C	intact:EBI-11522250|ensembl:ENSP00000406286	psi-mi:rv161_yeast(display_long)|uniprotkb:RVS161(gene name)|psi-mi:RVS161(display_short)|uniprotkb:END6(gene name synonym)|uniprotkb:SPE161(gene name synonym)|uniprotkb:YCR009C(locus name)|uniprotkb:YCR9C(orf name)	psi-mi:o15156-2(display_long)|uniprotkb:ZBTB7B(gene name)|psi-mi:ZBTB7B(display_short)|uniprotkb:Krueppel-related zinc finger protein cKrox(gene name synonym)|uniprotkb:T-helper-inducing POZ/Krueppel-like factor(gene name synonym)|uniprotkb:ZBTB15(gene name synonym)|uniprotkb:ZFP67(gene name synonym)|uniprotkb:ZNF857B(gene name synonym)|uniprotkb:Zinc finger and BTB domain-containing protein 15(gene name synonym)|uniprotkb:Zinc finger protein 67 homolog(gene name synonym)|uniprotkb:Zinc finger protein 857B(gene name synonym)|uniprotkb:Zinc finger protein Th-POK(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11524234|imex:IM-24995-202	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YCR009C(gene)|ensemblfungi:YCR009C_mRNA(transcript)|go:"GO:0000747"(conjugation with cellular fusion)|go:"GO:0005829"(cytosol)|go:"GO:0005937"(mating projection)|go:"GO:0006897"(endocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030479"(actin cortical patch)|go:"GO:0031097"(medial cortex)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0042594"(response to starvation)|go:"GO:0043332"(mating projection tip)|go:"GO:0045121"(membrane raft)|go:"GO:0051666"(actin cortical patch localization)|go:"GO:0060988"(lipid tube assembly)|go:"GO:0097320"(plasma membrane tubulation)|go:"GO:1990528"(Rvs161p-Rvs167p complex)|interpro:IPR004148(BAR)|interpro:IPR027267|go:"GO:0006970"(response to osmotic stress)|interpro:IPR037429|refseq:NP_009935.1|sgd:S000000602|mint:P25343|dip:DIP-1601N|sgd:YCR009C(identity)	intact:EBI-740434(isoform-parent)|ensembl:ENSG00000160685(gene)|ensembl:ENST00000417934(transcript)|uniprotkb:O15156-2(isoform-parent)|entrezgene/locuslink:51043(identity)	-	crc64:B35EA00E0C900E2D	isoform-comment:No experimental confirmation available.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:IdjO8RS5vcYMeGxuoPoa/5e7QJQ559292	rogid:41NEFYyprTXI+fOHVFh78TPKF289606	intact-crc:728B7BBADCF7BE81|rigid:gM6N97nvBxr3+9i2/GfwyjGQenQ	false	-	sufficient binding region:35-573	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P14136	uniprotkb:P25343	intact:EBI-744302|uniprotkb:Q53H98|uniprotkb:Q5D055|uniprotkb:Q6ZQS3|uniprotkb:Q7Z5J6|uniprotkb:Q7Z5J7|uniprotkb:Q96KS4|uniprotkb:Q96P18|uniprotkb:Q9UFD0|uniprotkb:B2RD44|uniprotkb:D3DX59|intact:EBI-3909365|uniprotkb:E9PAX3|ensembl:ENSP00000466598|uniprotkb:A7REI1	intact:EBI-14490|uniprotkb:D6VR18|ensemblfungi:YCR009C	psi-mi:gfap_human(display_long)|uniprotkb:GFAP(gene name)|psi-mi:GFAP(display_short)	psi-mi:rv161_yeast(display_long)|uniprotkb:RVS161(gene name)|psi-mi:RVS161(display_short)|uniprotkb:END6(gene name synonym)|uniprotkb:SPE161(gene name synonym)|uniprotkb:YCR009C(locus name)|uniprotkb:YCR9C(orf name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11524245|imex:IM-24995-203	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001124491.1|refseq:NP_001229305.1|refseq:NP_002046.1|ensembl:ENSG00000131095(gene)|ensembl:ENST00000588735(transcript)|go:"GO:0005178"(integrin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0009611"(response to wounding)|go:"GO:0010467"(gene expression)|go:"GO:0010625"(positive regulation of Schwann cell proliferation)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0014002"(astrocyte development)|go:"GO:0019900"(kinase binding)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0031102"(neuron projection regeneration)|go:"GO:0042802"(identical protein binding)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0044297"(cell body)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0051580"(regulation of neurotransmitter uptake)|go:"GO:0060020"(Bergmann glial cell differentiation)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0070779"(D-aspartate import across plasma membrane)|go:"GO:0097450"(astrocyte end-foot)|go:"GO:0098574"(cytoplasmic side of lysosomal membrane)|go:"GO:1904714"(regulation of chaperone-mediated autophagy)|interpro:IPR006821(Intermediate filament, DNA-binding region)|interpro:IPR018039|interpro:IPR027701|interpro:IPR039008|mint:P14136|rcsb pdb:6A9P|reactome:R-HSA-1251985|reactome:R-HSA-9613829|entrezgene/locuslink:2670(identity)	ensemblfungi:YCR009C(gene)|ensemblfungi:YCR009C_mRNA(transcript)|go:"GO:0000747"(conjugation with cellular fusion)|go:"GO:0005829"(cytosol)|go:"GO:0005937"(mating projection)|go:"GO:0006897"(endocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030479"(actin cortical patch)|go:"GO:0031097"(medial cortex)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0042594"(response to starvation)|go:"GO:0043332"(mating projection tip)|go:"GO:0045121"(membrane raft)|go:"GO:0051666"(actin cortical patch localization)|go:"GO:0060988"(lipid tube assembly)|go:"GO:0097320"(plasma membrane tubulation)|go:"GO:1990528"(Rvs161p-Rvs167p complex)|interpro:IPR004148(BAR)|interpro:IPR027267|go:"GO:0006970"(response to osmotic stress)|interpro:IPR037429|refseq:NP_009935.1|sgd:S000000602|mint:P25343|dip:DIP-1601N|sgd:YCR009C(identity)	-	-	crc64:B35EA00E0C900E2D	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Pz4JW0WjMjBYILTDSX9jUmMqWhg9606	rogid:IdjO8RS5vcYMeGxuoPoa/5e7QJQ559292	intact-crc:96BE75A7650E04CB|rigid:WHUjOicWVQnQ5I/yFWGjBsSZtUQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P25343	uniprotkb:Q15427	intact:EBI-14490|uniprotkb:D6VR18|ensemblfungi:YCR009C	intact:EBI-348469|ensembl:ENSP00000271628|intact:EBI-1047735|uniprotkb:Q5SZ63	psi-mi:rv161_yeast(display_long)|uniprotkb:RVS161(gene name)|psi-mi:RVS161(display_short)|uniprotkb:END6(gene name synonym)|uniprotkb:SPE161(gene name synonym)|uniprotkb:YCR009C(locus name)|uniprotkb:YCR9C(orf name)	psi-mi:sf3b4_human(display_long)|uniprotkb:SF3B4(gene name)|psi-mi:SF3B4(display_short)|uniprotkb:SAP49(gene name synonym)|uniprotkb:Spliceosome-associated protein 49(gene name synonym)|uniprotkb:Pre-mRNA-splicing factor SF3b 49 kDa subunit(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11524254|imex:IM-24995-204	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YCR009C(gene)|ensemblfungi:YCR009C_mRNA(transcript)|go:"GO:0000747"(conjugation with cellular fusion)|go:"GO:0005829"(cytosol)|go:"GO:0005937"(mating projection)|go:"GO:0006897"(endocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030479"(actin cortical patch)|go:"GO:0031097"(medial cortex)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0042594"(response to starvation)|go:"GO:0043332"(mating projection tip)|go:"GO:0045121"(membrane raft)|go:"GO:0051666"(actin cortical patch localization)|go:"GO:0060988"(lipid tube assembly)|go:"GO:0097320"(plasma membrane tubulation)|go:"GO:1990528"(Rvs161p-Rvs167p complex)|interpro:IPR004148(BAR)|interpro:IPR027267|go:"GO:0006970"(response to osmotic stress)|interpro:IPR037429|refseq:NP_009935.1|sgd:S000000602|mint:P25343|dip:DIP-1601N|sgd:YCR009C(identity)	refseq:NP_005841.1|ensembl:ENSG00000143368(gene)|ensembl:ENST00000271628(transcript)|rcsb pdb:6QX9|rcsb pdb:6Y53|rcsb pdb:6Y5Q|rcsb pdb:7ABG|rcsb pdb:7ABH|rcsb pdb:7ABI|rcsb pdb:7DVQ|reactome:R-HSA-72163|reactome:R-HSA-72165|rcsb pdb:6AHD|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:1990935"(splicing factor binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034158|go:"GO:0000375"(RNA splicing, via transesterification reactions)|interpro:IPR034159|interpro:IPR035979|mint:Q15427|rcsb pdb:1X5T|rcsb pdb:5GVQ|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|entrezgene/locuslink:10262(identity)	-	crc64:B35EA00E0C900E2D	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:IdjO8RS5vcYMeGxuoPoa/5e7QJQ559292	rogid:Jgy6WmBFKkphpZLLte2GgsagUVI9606	intact-crc:1F536A2218DF381C|rigid:bknMPZefJNeyCajFqg2U1zUynFk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O14641	uniprotkb:P25372	intact:EBI-740850|ensembl:ENSP00000005340|uniprotkb:Q53XM0|uniprotkb:D3DTN3	intact:EBI-19616|uniprotkb:D6VR84|ensemblfungi:YCR083W	psi-mi:dvl2_human(display_long)|uniprotkb:DSH homolog 2(gene name synonym)|uniprotkb:DVL2(gene name)|psi-mi:DVL2(display_short)	psi-mi:trx3_yeast(display_long)|uniprotkb:TRX3(gene name)|psi-mi:TRX3(display_short)|uniprotkb:YCR83W(orf name)|uniprotkb:YCR083W(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11524313|imex:IM-24995-210	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004413.1|ensembl:ENSG00000004975(gene)|ensembl:ENST00000005340(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005109"(frizzled binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0007507"(heart development)|go:"GO:0016235"(aggresome)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044340"(canonical Wnt signaling pathway involved in regulation of cell proliferation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0150012"(positive regulation of neuron projection arborization)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008341(Dishevelled-2 region)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:O14641|rcsb pdb:2REY|rcsb pdb:3CBX|rcsb pdb:3CBY|rcsb pdb:3CBZ|rcsb pdb:3CC0|rcsb pdb:4WIP|rcsb pdb:5LNP|rcsb pdb:5SUY|rcsb pdb:5SUZ|rcsb pdb:6IW3|rcsb pdb:6JCK|reactome:R-HSA-201681|reactome:R-HSA-201688|reactome:R-HSA-2028269|reactome:R-HSA-4086400|reactome:R-HSA-4608870|reactome:R-HSA-4641258|reactome:R-HSA-4641262|reactome:R-HSA-5099900|reactome:R-HSA-5368598|reactome:R-HSA-5663220|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9673324|ensembl:ENSP00000005340|dip:DIP-34433N|entrezgene/locuslink:1856(identity)	interpro:IPR036249|refseq:NP_010006.1|sgd:S000000679|interpro:IPR017937|interpro:IPR013766(Thioredoxin domain)|rcsb pdb:2OE0|rcsb pdb:2OE1|rcsb pdb:2OE3|ensemblfungi:YCR083W(gene)|ensemblfungi:YCR083W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0015036"(disulfide oxidoreductase activity)|go:"GO:0034599"(cellular response to oxidative stress)|rcsb pdb:5YKW|sgd:YCR083W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:2Vdc8oRnT4Mz/j+EXQXrL3AszOc9606	rogid:g0xjGf9GvJRl8iv2qoT5tOs7jXI559292	intact-crc:40B3A93CD784935E|rigid:qW2yYituG07tnqilIn18HK/zMxA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P63279	uniprotkb:P25354	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	intact:EBI-21848|uniprotkb:Q70DH1|uniprotkb:Q70DH4|uniprotkb:Q70DH6|uniprotkb:D6VR16|ensemblfungi:YCR007C	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:ycp7_yeast(display_long)|uniprotkb:YCR045(orf name)|uniprotkb:YCR7C(orf name)|uniprotkb:YCR007C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11524281|imex:IM-24995-207	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N|entrezgene/locuslink:7329(identity)	refseq:NP_009933.1|sgd:S000000600|dip:DIP-4043N|ensemblfungi:YCR007C(gene)|ensemblfungi:YCR007C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|interpro:IPR001142(Yeast membrane protein DUP)|sgd:YCR007C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	rogid:5AYWvsKbIkyI0AaAP811MKfdVXI559292	intact-crc:EE3C412FD61BB90B|rigid:R1WRsBaowNpKKdpBR0jtU7mUOMU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P25372	intact:EBI-11524292	intact:EBI-19616|uniprotkb:D6VR84|ensemblfungi:YCR083W	-	psi-mi:trx3_yeast(display_long)|uniprotkb:TRX3(gene name)|psi-mi:TRX3(display_short)|uniprotkb:YCR83W(orf name)|uniprotkb:YCR083W(locus name)	psi-mi:trip6(display_short)|psi-mi:EBI-11524292(display_long)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11524290|imex:IM-24995-208	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR036249|refseq:NP_010006.1|sgd:S000000679|interpro:IPR017937|interpro:IPR013766(Thioredoxin domain)|rcsb pdb:2OE0|rcsb pdb:2OE1|rcsb pdb:2OE3|ensemblfungi:YCR083W(gene)|ensemblfungi:YCR083W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0015036"(disulfide oxidoreductase activity)|go:"GO:0034599"(cellular response to oxidative stress)|rcsb pdb:5YKW|sgd:YCR083W(identity)	entrezgene/locuslink:7205(identity)	-	-	no-uniprot-update:	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:g0xjGf9GvJRl8iv2qoT5tOs7jXI559292	rogid:S6W5lkNauGhNejln9bTVoqZjNL49606	intact-crc:7201FC5F3C37ABDC|rigid:bwExTIDGQGpNGL73rMESgXrHyc0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q08379	uniprotkb:P25372	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	intact:EBI-19616|uniprotkb:D6VR84|ensemblfungi:YCR083W	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:trx3_yeast(display_long)|uniprotkb:TRX3(gene name)|psi-mi:TRX3(display_short)|uniprotkb:YCR83W(orf name)|uniprotkb:YCR083W(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11524302|imex:IM-24995-209	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N|entrezgene/locuslink:2801(identity)	interpro:IPR036249|refseq:NP_010006.1|sgd:S000000679|interpro:IPR017937|interpro:IPR013766(Thioredoxin domain)|rcsb pdb:2OE0|rcsb pdb:2OE1|rcsb pdb:2OE3|ensemblfungi:YCR083W(gene)|ensemblfungi:YCR083W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0015036"(disulfide oxidoreductase activity)|go:"GO:0034599"(cellular response to oxidative stress)|rcsb pdb:5YKW|sgd:YCR083W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2017/05/26	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	rogid:g0xjGf9GvJRl8iv2qoT5tOs7jXI559292	intact-crc:A436ED1B13F9D4EE|rigid:nwv71IkwKmL4x3nV92ZKFMB1U+U	false	sufficient binding region:383-1002	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12800	uniprotkb:P25372	intact:EBI-717422|uniprotkb:Q12801|uniprotkb:Q9UD77|uniprotkb:A8K5E9|uniprotkb:Q9UD75|ensembl:ENSP00000257915	intact:EBI-19616|uniprotkb:D6VR84|ensemblfungi:YCR083W	psi-mi:tfcp2_human(display_long)|uniprotkb:Transcription factor LSF(gene name synonym)|uniprotkb:SAA3 enhancer factor(gene name synonym)|uniprotkb:TFCP2(gene name)|psi-mi:TFCP2(display_short)|uniprotkb:LSF(gene name synonym)|uniprotkb:SEF(gene name synonym)	psi-mi:trx3_yeast(display_long)|uniprotkb:TRX3(gene name)|psi-mi:TRX3(display_short)|uniprotkb:YCR83W(orf name)|uniprotkb:YCR083W(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11524369|imex:IM-24995-216	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001166923.1|refseq:NP_001166924.1|refseq:NP_005644.2|ensembl:ENSG00000135457(gene)|ensembl:ENST00000257915(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR007604(CP2 transcription factor)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR037599|interpro:IPR041418|mint:Q12800|entrezgene/locuslink:7024(identity)	interpro:IPR036249|refseq:NP_010006.1|sgd:S000000679|interpro:IPR017937|interpro:IPR013766(Thioredoxin domain)|rcsb pdb:2OE0|rcsb pdb:2OE1|rcsb pdb:2OE3|ensemblfungi:YCR083W(gene)|ensemblfungi:YCR083W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0015036"(disulfide oxidoreductase activity)|go:"GO:0034599"(cellular response to oxidative stress)|rcsb pdb:5YKW|sgd:YCR083W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:M7mQ08NDYxuawmUEKRgjSdIr+Og9606	rogid:g0xjGf9GvJRl8iv2qoT5tOs7jXI559292	intact-crc:D6A91FF4A4766597|rigid:32XPbIfd3r2o9unzkwhEZF9w+Kk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P25372	uniprotkb:P19012	intact:EBI-19616|uniprotkb:D6VR84|ensemblfungi:YCR083W	intact:EBI-739566|uniprotkb:Q53XV8|uniprotkb:Q9BUG4|uniprotkb:B3KQY1|uniprotkb:B3KRA2|uniprotkb:E0CX14|ensembl:ENSP00000254043|ensembl:ENSP00000377546	psi-mi:trx3_yeast(display_long)|uniprotkb:TRX3(gene name)|psi-mi:TRX3(display_short)|uniprotkb:YCR83W(orf name)|uniprotkb:YCR083W(locus name)	psi-mi:k1c15_human(display_long)|uniprotkb:KRT15(gene name)|psi-mi:KRT15(display_short)|uniprotkb:KRTB(gene name synonym)|uniprotkb:Cytokeratin-15(gene name synonym)|uniprotkb:Keratin-15(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11524360|imex:IM-24995-215	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR036249|refseq:NP_010006.1|sgd:S000000679|interpro:IPR017937|interpro:IPR013766(Thioredoxin domain)|rcsb pdb:2OE0|rcsb pdb:2OE1|rcsb pdb:2OE3|ensemblfungi:YCR083W(gene)|ensemblfungi:YCR083W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0015036"(disulfide oxidoreductase activity)|go:"GO:0034599"(cellular response to oxidative stress)|rcsb pdb:5YKW|sgd:YCR083W(identity)	refseq:NP_002266.2|ensembl:ENSG00000171346(gene)|ensembl:ENST00000254043(transcript)|ensembl:ENST00000393976(transcript)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0008544"(epidermis development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097110"(scaffold protein binding)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR039008|mint:P19012|reactome:R-HSA-6805567|reactome:R-HSA-6809371|entrezgene/locuslink:3866(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:g0xjGf9GvJRl8iv2qoT5tOs7jXI559292	rogid:WrZQBYQvrWcfrR5ojWXrXp6spPE9606	intact-crc:D2EC408417DDA523|rigid:rhj9ZjA14YeiQhCoKba8ZQBdWXI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P25372	uniprotkb:O43379	intact:EBI-19616|uniprotkb:D6VR84|ensemblfungi:YCR083W	intact:EBI-714790|uniprotkb:Q63HP9|uniprotkb:Q659D7|uniprotkb:Q8NBF7|uniprotkb:Q96AD9|intact:EBI-2563293|ensembl:ENSP00000270301	psi-mi:trx3_yeast(display_long)|uniprotkb:TRX3(gene name)|psi-mi:TRX3(display_short)|uniprotkb:YCR83W(orf name)|uniprotkb:YCR083W(locus name)	psi-mi:wdr62_human(display_long)|uniprotkb:WDR62(gene name)|psi-mi:WDR62(display_short)|uniprotkb:C19orf14(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11524322|imex:IM-24995-211	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR036249|refseq:NP_010006.1|sgd:S000000679|interpro:IPR017937|interpro:IPR013766(Thioredoxin domain)|rcsb pdb:2OE0|rcsb pdb:2OE1|rcsb pdb:2OE3|ensemblfungi:YCR083W(gene)|ensemblfungi:YCR083W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0015036"(disulfide oxidoreductase activity)|go:"GO:0034599"(cellular response to oxidative stress)|rcsb pdb:5YKW|sgd:YCR083W(identity)	go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007099"(centriole replication)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0022008"(neurogenesis)|go:"GO:0034451"(centriolar satellite)|interpro:IPR001680(WD40 repeat)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR024977|interpro:IPR036322|mint:O43379|go:"GO:0005813"(centrosome)|ensembl:ENSG00000075702(gene)|ensembl:ENST00000270301(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|refseq:NP_001077430.1|refseq:NP_775907.4|refseq:XP_016882154.1|dip:DIP-56792N|entrezgene/locuslink:284403(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:g0xjGf9GvJRl8iv2qoT5tOs7jXI559292	rogid:bKUivd80luQPFZHsU9mDdwyGwi89606	intact-crc:36CB0B679ABFC80E|rigid:ItU3uRHsL/1Qfpgrmgytvc+ufWg	false	-	sufficient binding region:889-1518	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P01100	uniprotkb:P25372	intact:EBI-852851|uniprotkb:P18849|uniprotkb:A8K4E2|uniprotkb:B4DQ65|ensembl:ENSP00000306245	intact:EBI-19616|uniprotkb:D6VR84|ensemblfungi:YCR083W	psi-mi:fos_human(display_long)|uniprotkb:Cellular oncogene fos(gene name synonym)|uniprotkb:G0/G1 switch regulatory protein 7(gene name synonym)|uniprotkb:FOS(gene name)|psi-mi:FOS(display_short)|uniprotkb:G0S7(gene name synonym)	psi-mi:trx3_yeast(display_long)|uniprotkb:TRX3(gene name)|psi-mi:TRX3(display_short)|uniprotkb:YCR83W(orf name)|uniprotkb:YCR083W(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11524342|imex:IM-24995-213	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005243.1|dip:DIP-1047N|ensembl:ENSG00000170345(gene)|ensembl:ENST00000303562(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001661"(conditioned taste aversion)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006306"(DNA methylation)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006954"(inflammatory response)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007399"(nervous system development)|go:"GO:0007565"(female pregnancy)|go:"GO:0007568"(aging)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009409"(response to cold)|go:"GO:0009416"(response to light stimulus)|go:"GO:0009629"(response to gravity)|go:"GO:0009636"(response to toxic substance)|go:"GO:0016020"(membrane)|go:"GO:0030431"(sleep)|go:"GO:0031668"(cellular response to extracellular stimulus)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032570"(response to progesterone)|go:"GO:0032870"(cellular response to hormone stimulus)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034097"(response to cytokine)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035902"(response to immobilization stress)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0035976"(transcription factor AP-1 complex)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045672"(positive regulation of osteoclast differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051412"(response to corticosterone)|go:"GO:0051591"(response to cAMP)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000837(Fos transforming protein)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029816|rcsb pdb:1A02|rcsb pdb:1FOS|rcsb pdb:1S9K|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2871796|reactome:R-HSA-450341|reactome:R-HSA-6785807|reactome:R-HSA-6796648|reactome:R-HSA-9018519|reactome:R-HSA-9031628|reactome:R-HSA-9634638|entrezgene/locuslink:2353(identity)	interpro:IPR036249|refseq:NP_010006.1|sgd:S000000679|interpro:IPR017937|interpro:IPR013766(Thioredoxin domain)|rcsb pdb:2OE0|rcsb pdb:2OE1|rcsb pdb:2OE3|ensemblfungi:YCR083W(gene)|ensemblfungi:YCR083W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0015036"(disulfide oxidoreductase activity)|go:"GO:0034599"(cellular response to oxidative stress)|rcsb pdb:5YKW|sgd:YCR083W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:R09jzTKeAyzIQYTQAsps2UWFyFE9606	rogid:g0xjGf9GvJRl8iv2qoT5tOs7jXI559292	intact-crc:FD762F55761A2DBC|rigid:I9lOBxbMyqcagDUwjOiVWfRerZc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O95073-2	uniprotkb:P25372	intact:EBI-10696047	intact:EBI-19616|uniprotkb:D6VR84|ensemblfungi:YCR083W	psi-mi:o95073-2(display_long)|uniprotkb:FSBP(gene name)|psi-mi:FSBP(display_short)	psi-mi:trx3_yeast(display_long)|uniprotkb:TRX3(gene name)|psi-mi:TRX3(display_short)|uniprotkb:YCR83W(orf name)|uniprotkb:YCR083W(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11524333|imex:IM-24995-212	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-1059030(isoform-parent)|uniprotkb:O95073-2(isoform-parent)|entrezgene/locuslink:25788(identity)	interpro:IPR036249|refseq:NP_010006.1|sgd:S000000679|interpro:IPR017937|interpro:IPR013766(Thioredoxin domain)|rcsb pdb:2OE0|rcsb pdb:2OE1|rcsb pdb:2OE3|ensemblfungi:YCR083W(gene)|ensemblfungi:YCR083W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0015036"(disulfide oxidoreductase activity)|go:"GO:0034599"(cellular response to oxidative stress)|rcsb pdb:5YKW|sgd:YCR083W(identity)	-	isoform-comment:No experimental confirmation available.	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:j4ktleFZa7rAjRFENAKAGdAd+Fs9606	rogid:g0xjGf9GvJRl8iv2qoT5tOs7jXI559292	intact-crc:D720544AC5AC4D4C|rigid:pVxgkpSkBuFL5XF5oz/yAWRx/4Y	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P14373	uniprotkb:P25372	intact:EBI-719493|uniprotkb:A2BE15|uniprotkb:Q5RJA8|uniprotkb:Q5ST26|uniprotkb:Q6LA73|uniprotkb:Q6NXR9|uniprotkb:Q9BZY6|uniprotkb:Q9UJL3|ensembl:ENSP00000383555|ensembl:ENSP00000392787|ensembl:ENSP00000405229|ensembl:ENSP00000414793|ensembl:ENSP00000366404	intact:EBI-19616|uniprotkb:D6VR84|ensemblfungi:YCR083W	psi-mi:tri27_human(display_long)|uniprotkb:TRIM27(gene name)|psi-mi:TRIM27(display_short)|uniprotkb:RNF76(gene name synonym)|uniprotkb:RFP(gene name synonym)|uniprotkb:Ret finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 27(gene name synonym)|uniprotkb:RING finger protein 76(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM27(gene name synonym)	psi-mi:trx3_yeast(display_long)|uniprotkb:TRX3(gene name)|psi-mi:TRX3(display_short)|uniprotkb:YCR83W(orf name)|uniprotkb:YCR083W(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11524351|imex:IM-24995-214	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006501.1|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0090281"(negative regulation of calcium ion import)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR020457|interpro:IPR035791|interpro:IPR043136|mint:P14373|reactome:R-HSA-3232142|reactome:R-HSA-9635465|reactome:R-HSA-8948751|ensembl:ENSG00000204713(gene)|ensembl:ENSG00000215641(gene)|ensembl:ENSG00000229006(gene)|ensembl:ENSG00000234495(gene)|ensembl:ENSG00000237071(gene)|ensembl:ENST00000377199(transcript)|ensembl:ENST00000400720(transcript)|ensembl:ENST00000431123(transcript)|ensembl:ENST00000435528(transcript)|ensembl:ENST00000437160(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001650"(fibrillar center)|go:"GO:0002820"(negative regulation of adaptive immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|entrezgene/locuslink:5987(identity)	interpro:IPR036249|refseq:NP_010006.1|sgd:S000000679|interpro:IPR017937|interpro:IPR013766(Thioredoxin domain)|rcsb pdb:2OE0|rcsb pdb:2OE1|rcsb pdb:2OE3|ensemblfungi:YCR083W(gene)|ensemblfungi:YCR083W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0015036"(disulfide oxidoreductase activity)|go:"GO:0034599"(cellular response to oxidative stress)|rcsb pdb:5YKW|sgd:YCR083W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:dsfH5OUghD8KSaTz1SFw9OYVTK49606	rogid:g0xjGf9GvJRl8iv2qoT5tOs7jXI559292	intact-crc:768AA655224C69B3|rigid:or242VUGNkFq7Yqk1gx8Af1pjBQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8IUQ4-2	uniprotkb:P25372	intact:EBI-11522811|ensembl:ENSP00000349156	intact:EBI-19616|uniprotkb:D6VR84|ensemblfungi:YCR083W	psi-mi:q8iuq4-2(display_long)|uniprotkb:SIAH1(gene name)|psi-mi:SIAH1(display_short)|uniprotkb:HUMSIAH(gene name synonym)|uniprotkb:Seven in absentia homolog 1(gene name synonym)|uniprotkb:Siah-1a(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase SIAH1(gene name synonym)	psi-mi:trx3_yeast(display_long)|uniprotkb:TRX3(gene name)|psi-mi:TRX3(display_short)|uniprotkb:YCR83W(orf name)|uniprotkb:YCR083W(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11524419|imex:IM-24995-221	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-747107(isoform-parent)|ensembl:ENSG00000196470(gene)|ensembl:ENST00000356721(transcript)|uniprotkb:Q8IUQ4-2(isoform-parent)|entrezgene/locuslink:6477(identity)	interpro:IPR036249|refseq:NP_010006.1|sgd:S000000679|interpro:IPR017937|interpro:IPR013766(Thioredoxin domain)|rcsb pdb:2OE0|rcsb pdb:2OE1|rcsb pdb:2OE3|ensemblfungi:YCR083W(gene)|ensemblfungi:YCR083W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0015036"(disulfide oxidoreductase activity)|go:"GO:0034599"(cellular response to oxidative stress)|rcsb pdb:5YKW|sgd:YCR083W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:M4q06jVbWuq1mGMXvtuFBaMEgZM9606	rogid:g0xjGf9GvJRl8iv2qoT5tOs7jXI559292	intact-crc:406AD135FF14D58D|rigid:ag+O9md4JZaSgB2+97fHyAL1Ft8	false	sufficient binding region:32-313	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P25372	uniprotkb:Q5T124-6	intact:EBI-19616|uniprotkb:D6VR84|ensemblfungi:YCR083W	intact:EBI-11524408	psi-mi:trx3_yeast(display_long)|uniprotkb:TRX3(gene name)|psi-mi:TRX3(display_short)|uniprotkb:YCR83W(orf name)|uniprotkb:YCR083W(locus name)	psi-mi:q5t124-6(display_long)|uniprotkb:UBXN11(gene name)|psi-mi:UBXN11(display_short)|uniprotkb:Colorectal tumor-associated antigen COA-1(gene name synonym)|uniprotkb:SOC(gene name synonym)|uniprotkb:Socius(gene name synonym)|uniprotkb:UBX domain-containing protein 5(gene name synonym)|uniprotkb:UBXD5(gene name synonym)|uniprotkb:PP2243(orf name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11524406|imex:IM-24995-220	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR036249|refseq:NP_010006.1|sgd:S000000679|interpro:IPR017937|interpro:IPR013766(Thioredoxin domain)|rcsb pdb:2OE0|rcsb pdb:2OE1|rcsb pdb:2OE3|ensemblfungi:YCR083W(gene)|ensemblfungi:YCR083W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0015036"(disulfide oxidoreductase activity)|go:"GO:0034599"(cellular response to oxidative stress)|rcsb pdb:5YKW|sgd:YCR083W(identity)	intact:EBI-746004(isoform-parent)|uniprotkb:Q5T124-6(isoform-parent)|entrezgene/locuslink:91544(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:g0xjGf9GvJRl8iv2qoT5tOs7jXI559292	rogid:1YSjG/p2ihcjl4P8KdPCaX2HxiY9606	intact-crc:573DE57425D67F4F|rigid:u+mMQM8pDMXQxLofCI551fVRpVk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q13422-7	uniprotkb:P25372	intact:EBI-11522367|ensembl:ENSP00000352123|ensembl:ENSP00000413025	intact:EBI-19616|uniprotkb:D6VR84|ensemblfungi:YCR083W	psi-mi:q13422-7(display_long)|uniprotkb:IKZF1(gene name)|psi-mi:IKZF1(display_short)|uniprotkb:IK1(gene name synonym)|uniprotkb:IKAROS(gene name synonym)|uniprotkb:Ikaros family zinc finger protein 1(gene name synonym)|uniprotkb:LYF1(gene name synonym)|uniprotkb:Lymphoid transcription factor LyF-1(gene name synonym)|uniprotkb:ZNFN1A1(gene name synonym)	psi-mi:trx3_yeast(display_long)|uniprotkb:TRX3(gene name)|psi-mi:TRX3(display_short)|uniprotkb:YCR83W(orf name)|uniprotkb:YCR083W(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11524378|imex:IM-24995-217	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-745305(isoform-parent)|ensembl:ENSG00000185811(gene)|ensembl:ENST00000359197(transcript)|ensembl:ENST00000439701(transcript)|uniprotkb:Q13422-7(isoform-parent)|entrezgene/locuslink:10320(identity)	interpro:IPR036249|refseq:NP_010006.1|sgd:S000000679|interpro:IPR017937|interpro:IPR013766(Thioredoxin domain)|rcsb pdb:2OE0|rcsb pdb:2OE1|rcsb pdb:2OE3|ensemblfungi:YCR083W(gene)|ensemblfungi:YCR083W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0015036"(disulfide oxidoreductase activity)|go:"GO:0034599"(cellular response to oxidative stress)|rcsb pdb:5YKW|sgd:YCR083W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:ou/ovXYoMneBNVp4pj38VxenfyY9606	rogid:g0xjGf9GvJRl8iv2qoT5tOs7jXI559292	intact-crc:5B10CFCFD773CD17|rigid:hAtZFbHwprHaYM4ZMSZuJSh4SWk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P25372	uniprotkb:Q13643	intact:EBI-19616|uniprotkb:D6VR84|ensemblfungi:YCR083W	intact:EBI-741101|ensembl:ENSP00000362107|uniprotkb:Q6I9T0|uniprotkb:Q9BVA2|uniprotkb:D3DPT6	psi-mi:trx3_yeast(display_long)|uniprotkb:TRX3(gene name)|psi-mi:TRX3(display_short)|uniprotkb:YCR83W(orf name)|uniprotkb:YCR083W(locus name)	psi-mi:fhl3_human(display_long)|uniprotkb:FHL3(gene name)|psi-mi:FHL3(display_short)|uniprotkb:SLIM2(gene name synonym)|uniprotkb:Skeletal muscle LIM-protein 2(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11524387|imex:IM-24995-218	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR036249|refseq:NP_010006.1|sgd:S000000679|interpro:IPR017937|interpro:IPR013766(Thioredoxin domain)|rcsb pdb:2OE0|rcsb pdb:2OE1|rcsb pdb:2OE3|ensemblfungi:YCR083W(gene)|ensemblfungi:YCR083W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0015036"(disulfide oxidoreductase activity)|go:"GO:0034599"(cellular response to oxidative stress)|rcsb pdb:5YKW|sgd:YCR083W(identity)	refseq:NP_004459.2|ensembl:ENSG00000183386(gene)|ensembl:ENST00000373016(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005925"(focal adhesion)|go:"GO:0007517"(muscle organ development)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0046872"(metal ion binding)|interpro:IPR001781(Zinc finger, LIM-type)|mint:Q13643|rcsb pdb:1WYH|rcsb pdb:2CUQ|rcsb pdb:2EHE|interpro:IPR037987|refseq:NP_001230807.1|dip:DIP-42030N|entrezgene/locuslink:2275(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:g0xjGf9GvJRl8iv2qoT5tOs7jXI559292	rogid:RAo+b/VgFSnHSbgR+zXuxJvypxM9606	intact-crc:233DF9CB4B91697F|rigid:YeK0bnB8BkoATG8To/38UsoOSAI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P25372	uniprotkb:Q15654	intact:EBI-19616|uniprotkb:D6VR84|ensemblfungi:YCR083W	intact:EBI-742327|uniprotkb:O15170|uniprotkb:O15275|uniprotkb:Q9BTB2|uniprotkb:Q9BUE5|uniprotkb:Q9BXP3|uniprotkb:Q9UNT4|uniprotkb:A4D2E7|ensembl:ENSP00000200457|uniprotkb:F2ZC07|uniprotkb:F2ZC08	psi-mi:trx3_yeast(display_long)|uniprotkb:TRX3(gene name)|psi-mi:TRX3(display_short)|uniprotkb:YCR83W(orf name)|uniprotkb:YCR083W(locus name)	psi-mi:trip6_human(display_long)|uniprotkb:TRIP6(gene name)|psi-mi:TRIP6(display_short)|uniprotkb:OIP1(gene name synonym)|uniprotkb:Opa-interacting protein 1(gene name synonym)|uniprotkb:Zyxin-related protein 1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11524396|imex:IM-24995-219	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR036249|refseq:NP_010006.1|sgd:S000000679|interpro:IPR017937|interpro:IPR013766(Thioredoxin domain)|rcsb pdb:2OE0|rcsb pdb:2OE1|rcsb pdb:2OE3|ensemblfungi:YCR083W(gene)|ensemblfungi:YCR083W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0015036"(disulfide oxidoreductase activity)|go:"GO:0034599"(cellular response to oxidative stress)|rcsb pdb:5YKW|sgd:YCR083W(identity)	refseq:NP_003293.2|ensembl:ENSP00000200457|ensembl:ENST00000417475|ensembl:ENSP00000413817|ensembl:ENST00000437505|ensembl:ENSP00000410736|ensembl:ENST00000619988|ensembl:ENSP00000479865|ensembl:ENSG00000087077(gene)|ensembl:ENST00000200457(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003723"(RNA binding)|go:"GO:0005149"(interleukin-1 receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0019900"(kinase binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0043009"(chordate embryonic development)|go:"GO:0046872"(metal ion binding)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|interpro:IPR001781(Zinc finger, LIM-type)|mint:Q15654|rcsb pdb:1X61|rcsb pdb:2DLO|dip:DIP-34466N|entrezgene/locuslink:7205(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:g0xjGf9GvJRl8iv2qoT5tOs7jXI559292	rogid:9Okf3b6sMMwX5awAx991GN9iSsQ9606	intact-crc:18EA6222280DABD6|rigid:LQ5IHqe2DXnYjM69+r3vayu38eE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P25372	uniprotkb:Q8N9N5-2	intact:EBI-19616|uniprotkb:D6VR84|ensemblfungi:YCR083W	intact:EBI-11524452|ensembl:ENSP00000347125	psi-mi:trx3_yeast(display_long)|uniprotkb:TRX3(gene name)|psi-mi:TRX3(display_short)|uniprotkb:YCR83W(orf name)|uniprotkb:YCR083W(locus name)	psi-mi:q8n9n5-2(display_long)|uniprotkb:BANP(gene name)|psi-mi:BANP(display_short)|uniprotkb:BEN domain-containing protein 1(gene name synonym)|uniprotkb:BEND1(gene name synonym)|uniprotkb:Btg3-associated nuclear protein(gene name synonym)|uniprotkb:SMAR1(gene name synonym)|uniprotkb:Scaffold/matrix-associated region-1-binding protein(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11524456|imex:IM-24995-224	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR036249|refseq:NP_010006.1|sgd:S000000679|interpro:IPR017937|interpro:IPR013766(Thioredoxin domain)|rcsb pdb:2OE0|rcsb pdb:2OE1|rcsb pdb:2OE3|ensemblfungi:YCR083W(gene)|ensemblfungi:YCR083W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0015036"(disulfide oxidoreductase activity)|go:"GO:0034599"(cellular response to oxidative stress)|rcsb pdb:5YKW|sgd:YCR083W(identity)	ensembl:ENSG00000172530(gene)|ensembl:ENST00000355022(transcript)|intact:EBI-744695(isoform-parent)|uniprotkb:Q8N9N5-2(isoform-parent)|entrezgene/locuslink:54971(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:g0xjGf9GvJRl8iv2qoT5tOs7jXI559292	rogid:ESe6iCAhvq+i57fQHz3rGyg6UOo9606	intact-crc:DD5A1BA8C61B4C1D|rigid:D2t9mdT178XNXvZzowu3vAPVZPE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8IYA8	uniprotkb:P25372	intact:EBI-8638439|intact:EBI-28969497|ensembl:ENSP00000296449|ensembl:ENSP00000391788|ensembl:ENSP00000407837|uniprotkb:C9JJL0|uniprotkb:Q96LP7|intact:MINT-8162095|uniprotkb:Q05DG9	intact:EBI-19616|uniprotkb:D6VR84|ensemblfungi:YCR083W	psi-mi:iho1_human(display_long)|uniprotkb:IHO1(gene name)|psi-mi:IHO1(display_short)|uniprotkb:CCDC36(gene name synonym)|uniprotkb:Cancer/testis antigen 74(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 36(gene name synonym)	psi-mi:trx3_yeast(display_long)|uniprotkb:TRX3(gene name)|psi-mi:TRX3(display_short)|uniprotkb:YCR83W(orf name)|uniprotkb:YCR083W(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11524430|imex:IM-24995-222	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000296449|ensembl:ENST00000366429|ensembl:ENSP00000403700|ensembl:ENSP00000391788|ensembl:ENSP00000407837|ensembl:ENSG00000173421(gene)|ensembl:ENST00000296449(transcript)|ensembl:ENST00000438782(transcript)|ensembl:ENST00000452691(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0006310"(DNA recombination)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0042138"(meiotic DNA double-strand break formation)|go:"GO:0048477"(oogenesis)|go:"GO:0060629"(regulation of homologous chromosome segregation)|interpro:IPR031529|mint:Q8IYA8|refseq:XP_011531974.1|refseq:XP_011531975.1|refseq:NP_001128669.1|refseq:NP_835467.2|refseq:XP_006713187.1|entrezgene/locuslink:339834(identity)	interpro:IPR036249|refseq:NP_010006.1|sgd:S000000679|interpro:IPR017937|interpro:IPR013766(Thioredoxin domain)|rcsb pdb:2OE0|rcsb pdb:2OE1|rcsb pdb:2OE3|ensemblfungi:YCR083W(gene)|ensemblfungi:YCR083W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0015036"(disulfide oxidoreductase activity)|go:"GO:0034599"(cellular response to oxidative stress)|rcsb pdb:5YKW|sgd:YCR083W(identity)	-	comment:mint	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:+TNQLExkhmC1NWqsE240Cx7zFVU9606	rogid:g0xjGf9GvJRl8iv2qoT5tOs7jXI559292	intact-crc:E1A352740BEF21DE|rigid:2zq189Faq2pyv39vLJcAMbQ4yiY	false	sufficient binding region:11-594	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P25372	uniprotkb:Q8N7W2-2	intact:EBI-19616|uniprotkb:D6VR84|ensemblfungi:YCR083W	intact:EBI-10181188|ensembl:ENSP00000367868	psi-mi:trx3_yeast(display_long)|uniprotkb:TRX3(gene name)|psi-mi:TRX3(display_short)|uniprotkb:YCR83W(orf name)|uniprotkb:YCR083W(locus name)	psi-mi:q8n7w2-2(display_long)|uniprotkb:C10orf30(gene name synonym)|uniprotkb:BEND7(gene name)|psi-mi:BEND7(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11524441|imex:IM-24995-223	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR036249|refseq:NP_010006.1|sgd:S000000679|interpro:IPR017937|interpro:IPR013766(Thioredoxin domain)|rcsb pdb:2OE0|rcsb pdb:2OE1|rcsb pdb:2OE3|ensemblfungi:YCR083W(gene)|ensemblfungi:YCR083W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0015036"(disulfide oxidoreductase activity)|go:"GO:0034599"(cellular response to oxidative stress)|rcsb pdb:5YKW|sgd:YCR083W(identity)	ensembl:ENSG00000165626(gene)|ensembl:ENST00000378605(transcript)|intact:EBI-743382(isoform-parent)|uniprotkb:Q8N7W2-2(isoform-parent)|entrezgene/locuslink:222389(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:g0xjGf9GvJRl8iv2qoT5tOs7jXI559292	rogid:p6qrTn80hLyVU0W2Tvwn50Q4m5I9606	intact-crc:A44693846F832D02|rigid:o0fB5iTlqwudH6QuYtl3LKu7IBE	false	-	sufficient binding region:10-374	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9NYB9-2	uniprotkb:P25372	intact:EBI-11096309|ensembl:ENSP00000261017	intact:EBI-19616|uniprotkb:D6VR84|ensemblfungi:YCR083W	psi-mi:q9nyb9-2(display_long)|uniprotkb:ABI2(gene name)|psi-mi:ABI2(display_short)|uniprotkb:ARGBPIA(gene name synonym)|uniprotkb:Abelson interactor 2(gene name synonym)|uniprotkb:Abl-binding protein 3(gene name synonym)|uniprotkb:Arg-binding protein 1(gene name synonym)	psi-mi:trx3_yeast(display_long)|uniprotkb:TRX3(gene name)|psi-mi:TRX3(display_short)|uniprotkb:YCR83W(orf name)|uniprotkb:YCR083W(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11524514|imex:IM-24995-230	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-743598(isoform-parent)|ensembl:ENSG00000138443(gene)|ensembl:ENST00000261017(transcript)|uniprotkb:Q9NYB9-2(isoform-parent)|entrezgene/locuslink:10152(identity)	interpro:IPR036249|refseq:NP_010006.1|sgd:S000000679|interpro:IPR017937|interpro:IPR013766(Thioredoxin domain)|rcsb pdb:2OE0|rcsb pdb:2OE1|rcsb pdb:2OE3|ensemblfungi:YCR083W(gene)|ensemblfungi:YCR083W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0015036"(disulfide oxidoreductase activity)|go:"GO:0034599"(cellular response to oxidative stress)|rcsb pdb:5YKW|sgd:YCR083W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:VNi9aUeavD8+CCi+n1DXS+7mmbs9606	rogid:g0xjGf9GvJRl8iv2qoT5tOs7jXI559292	intact-crc:BAA5E53BC113A253|rigid:nwQyVIFS3EIBtCZK24g9kspA1yM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9NVV9	uniprotkb:P25372	intact:EBI-741515|uniprotkb:Q53FQ1|uniprotkb:Q6IA99|ensembl:ENSP00000254250|uniprotkb:A6NCB6|uniprotkb:D3DSY5|uniprotkb:H9KV49	intact:EBI-19616|uniprotkb:D6VR84|ensemblfungi:YCR083W	psi-mi:thap1_human(display_long)|uniprotkb:THAP1(gene name)|psi-mi:THAP1(display_short)	psi-mi:trx3_yeast(display_long)|uniprotkb:TRX3(gene name)|psi-mi:TRX3(display_short)|uniprotkb:YCR83W(orf name)|uniprotkb:YCR083W(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11524505|imex:IM-24995-229	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060575.1|ensembl:ENSG00000131931(gene)|ensembl:ENST00000254250(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001650"(fibrillar center)|go:"GO:0001935"(endothelial cell proliferation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007049"(cell cycle)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016605"(PML body)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR006612(Zinc finger, C2CH-type)|interpro:IPR026516|interpro:IPR038441|mint:Q9NVV9|rcsb pdb:2JTG|rcsb pdb:2KO0|rcsb pdb:2L1G|refseq:NP_945354.1|entrezgene/locuslink:55145(identity)	interpro:IPR036249|refseq:NP_010006.1|sgd:S000000679|interpro:IPR017937|interpro:IPR013766(Thioredoxin domain)|rcsb pdb:2OE0|rcsb pdb:2OE1|rcsb pdb:2OE3|ensemblfungi:YCR083W(gene)|ensemblfungi:YCR083W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0015036"(disulfide oxidoreductase activity)|go:"GO:0034599"(cellular response to oxidative stress)|rcsb pdb:5YKW|sgd:YCR083W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:/KO90pu5tBnIVq9SMx1JYPXFCEQ9606	rogid:g0xjGf9GvJRl8iv2qoT5tOs7jXI559292	intact-crc:C16E7FF45ABA58F7|rigid:gt2+hlOW9j2rlOxnM5RKPuBqBs4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8NF99-2	uniprotkb:P25372	intact:EBI-11524467|ensembl:ENSP00000261333	intact:EBI-19616|uniprotkb:D6VR84|ensemblfungi:YCR083W	psi-mi:q8nf99-2(display_long)|uniprotkb:ZNF47(gene name synonym)|uniprotkb:ZSCAN15(gene name synonym)|uniprotkb:Zinc finger and SCAN domain-containing protein 15(gene name synonym)|uniprotkb:Zinc finger protein 47(gene name synonym)|uniprotkb:ZNF397(gene name)|psi-mi:ZNF397(display_short)	psi-mi:trx3_yeast(display_long)|uniprotkb:TRX3(gene name)|psi-mi:TRX3(display_short)|uniprotkb:YCR83W(orf name)|uniprotkb:YCR083W(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11524465|imex:IM-24995-225	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-10213894(isoform-parent)|ensembl:ENSG00000186812(gene)|ensembl:ENST00000261333(transcript)|uniprotkb:Q8NF99-2(isoform-parent)|entrezgene/locuslink:84307(identity)	interpro:IPR036249|refseq:NP_010006.1|sgd:S000000679|interpro:IPR017937|interpro:IPR013766(Thioredoxin domain)|rcsb pdb:2OE0|rcsb pdb:2OE1|rcsb pdb:2OE3|ensemblfungi:YCR083W(gene)|ensemblfungi:YCR083W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0015036"(disulfide oxidoreductase activity)|go:"GO:0034599"(cellular response to oxidative stress)|rcsb pdb:5YKW|sgd:YCR083W(identity)	-	isoform-comment:No experimental confirmation available.	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:CGdD3rsdZjS7lhobp1xohK8ewPg9606	rogid:g0xjGf9GvJRl8iv2qoT5tOs7jXI559292	intact-crc:DB1A54C3F9397B25|rigid:b8nkJhl66djEkj5zPYbYu0c2h4g	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P25372	uniprotkb:Q96BR9	intact:EBI-19616|uniprotkb:D6VR84|ensemblfungi:YCR083W	intact:EBI-742740|uniprotkb:Q8IUL5|uniprotkb:Q8IWR9|uniprotkb:Q8N2Y5|uniprotkb:Q96BX0|ensembl:ENSP00000362609	psi-mi:trx3_yeast(display_long)|uniprotkb:TRX3(gene name)|psi-mi:TRX3(display_short)|uniprotkb:YCR83W(orf name)|uniprotkb:YCR083W(locus name)	psi-mi:zbt8a_human(display_long)|uniprotkb:ZBTB8A(gene name)|psi-mi:ZBTB8A(display_short)|uniprotkb:BOZF1(gene name synonym)|uniprotkb:BTB/POZ and zinc-finger domain-containing factor(gene name synonym)|uniprotkb:BTB/POZ and zinc-finger domains factor on chromosome 1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11524487|imex:IM-24995-227	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR036249|refseq:NP_010006.1|sgd:S000000679|interpro:IPR017937|interpro:IPR013766(Thioredoxin domain)|rcsb pdb:2OE0|rcsb pdb:2OE1|rcsb pdb:2OE3|ensemblfungi:YCR083W(gene)|ensemblfungi:YCR083W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0015036"(disulfide oxidoreductase activity)|go:"GO:0034599"(cellular response to oxidative stress)|rcsb pdb:5YKW|sgd:YCR083W(identity)	ensembl:ENSG00000160062(gene)|ensembl:ENST00000373510(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|refseq:NP_001035531.2|refseq:NP_001278425.1|entrezgene/locuslink:653121(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:g0xjGf9GvJRl8iv2qoT5tOs7jXI559292	rogid:tsrPT2tHvuBryODKgRXnceXz9s09606	intact-crc:3B9327554C1005EC|rigid:53vtLDth6ciX/tVN2LjZ7vKzi6s	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8NHQ1	uniprotkb:P25372	intact:EBI-739624|ensembl:ENSP00000264982|ensembl:ENSP00000419231|uniprotkb:Q96B31|uniprotkb:Q9H2C3|uniprotkb:Q9H2Z1|uniprotkb:Q9H940|uniprotkb:D3DNE9|uniprotkb:B7Z5I8|uniprotkb:B7Z7E8|uniprotkb:F5GZX8	intact:EBI-19616|uniprotkb:D6VR84|ensemblfungi:YCR083W	psi-mi:cep70_human(display_long)|uniprotkb:CEP70(gene name)|psi-mi:CEP70(display_short)|uniprotkb:BITE(gene name synonym)|uniprotkb:p10-binding protein(gene name synonym)	psi-mi:trx3_yeast(display_long)|uniprotkb:TRX3(gene name)|psi-mi:TRX3(display_short)|uniprotkb:YCR83W(orf name)|uniprotkb:YCR083W(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11524478|imex:IM-24995-226	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114107(gene)|ensembl:ENST00000264982(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|interpro:IPR019734|interpro:IPR037692|mint:Q8NHQ1|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|ensembl:ENST00000484888(transcript)|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_077817.2|refseq:XP_016862764.1|refseq:NP_001275893.1|refseq:NP_001275894.1|refseq:NP_001275895.1|refseq:NP_001275896.1|refseq:NP_001307527.1|refseq:NP_001307529.1|entrezgene/locuslink:80321(identity)	interpro:IPR036249|refseq:NP_010006.1|sgd:S000000679|interpro:IPR017937|interpro:IPR013766(Thioredoxin domain)|rcsb pdb:2OE0|rcsb pdb:2OE1|rcsb pdb:2OE3|ensemblfungi:YCR083W(gene)|ensemblfungi:YCR083W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0015036"(disulfide oxidoreductase activity)|go:"GO:0034599"(cellular response to oxidative stress)|rcsb pdb:5YKW|sgd:YCR083W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:S4yveQWcvdVtAUX65gqrJ5Dv0Mc9606	rogid:g0xjGf9GvJRl8iv2qoT5tOs7jXI559292	intact-crc:38CDC7A62CF1774A|rigid:USumgpr/MOfPlWxaf3nEjvTt9Sw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P25372	uniprotkb:Q9BRK4	intact:EBI-19616|uniprotkb:D6VR84|ensemblfungi:YCR083W	intact:EBI-741037|ensembl:ENSP00000359240|ensembl:ENSP00000359243|uniprotkb:Q8N3I0|uniprotkb:Q96J79|uniprotkb:Q96JL2|uniprotkb:B1AL14|uniprotkb:D3DR72	psi-mi:trx3_yeast(display_long)|uniprotkb:TRX3(gene name)|psi-mi:TRX3(display_short)|uniprotkb:YCR83W(orf name)|uniprotkb:YCR083W(locus name)	psi-mi:lzts2_human(display_long)|uniprotkb:Protein LAPSER1(gene name synonym)|uniprotkb:LZTS2(gene name)|psi-mi:LZTS2(display_short)|uniprotkb:KIAA1813(gene name synonym)|uniprotkb:LAPSER1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11524496|imex:IM-24995-228	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR036249|refseq:NP_010006.1|sgd:S000000679|interpro:IPR017937|interpro:IPR013766(Thioredoxin domain)|rcsb pdb:2OE0|rcsb pdb:2OE1|rcsb pdb:2OE3|ensemblfungi:YCR083W(gene)|ensemblfungi:YCR083W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0015036"(disulfide oxidoreductase activity)|go:"GO:0034599"(cellular response to oxidative stress)|rcsb pdb:5YKW|sgd:YCR083W(identity)	refseq:NP_115805.1|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030496"(midbody)|go:"GO:0031982"(vesicle)|go:"GO:0051013"(microtubule severing)|go:"GO:0051168"(nuclear export)|go:"GO:0051255"(spindle midzone assembly)|go:"GO:0060682"(primary ureteric bud growth)|go:"GO:0072197"(ureter morphogenesis)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|interpro:IPR028597|mint:Q9BRK4|ensembl:ENSG00000107816(gene)|ensembl:ENST00000370220(transcript)|ensembl:ENST00000370223(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0008285"(negative regulation of cell population proliferation)|refseq:XP_016872269.1|refseq:NP_001305028.1|refseq:NP_001305029.1|refseq:NP_001305030.1|refseq:XP_005270279.1|entrezgene/locuslink:84445(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:g0xjGf9GvJRl8iv2qoT5tOs7jXI559292	rogid:OaMJmnmfm6JniKUJeyg7fS6zRcw9606	intact-crc:CF94DCE60BD6B05C|rigid:v5gLRQMqyctMImI8qbPOhcFVTqE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P25377	uniprotkb:P43365	intact:EBI-2347652|uniprotkb:D6VRA5|ensemblfungi:YCR105W	intact:EBI-749530|uniprotkb:Q9NSD3|intact:EBI-10178394|uniprotkb:Q6FHH8|ensembl:ENSP00000350592|ensembl:ENSP00000377447|ensembl:ENSP00000377478	psi-mi:adh7_yeast(display_long)|uniprotkb:ADH7(gene name)|psi-mi:ADH7(display_short)|uniprotkb:NADP-dependent alcohol dehydrogenase VII(gene name synonym)|uniprotkb:YCR105W(locus name)	psi-mi:magac_human(display_long)|uniprotkb:MAGE-12 antigen(gene name synonym)|uniprotkb:MAGE12F antigen(gene name synonym)|uniprotkb:Cancer/testis antigen 1.12(gene name synonym)|uniprotkb:MAGEA12(gene name)|psi-mi:MAGEA12(display_short)|uniprotkb:MAGE12(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11524564|imex:IM-24995-235	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010030.1|sgd:S000000702|dip:DIP-7661N|mint:P25377|ensemblfungi:YCR105W(gene)|ensemblfungi:YCR105W_mRNA(transcript)|go:"GO:0006066"(alcohol metabolic process)|go:"GO:0008106"("alcohol dehydrogenase (NADP+) activity")|go:"GO:0008270"(zinc ion binding)|go:"GO:0016616"(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|interpro:IPR002328(Alcohol dehydrogenase, zinc-containing, conserved site)|interpro:IPR011032(GroES-like)|interpro:IPR013149(Alcohol dehydrogenase, zinc-binding)|interpro:IPR013154(Alcohol dehydrogenase GroES-like)|interpro:IPR020843|interpro:IPR029752|interpro:IPR036291|sgd:YCR105W(identity)	refseq:NP_001159858.1|refseq:NP_001159859.1|refseq:NP_005358.2|ensembl:ENSG00000213401(gene)|ensembl:ENST00000357916(transcript)|ensembl:ENST00000393869(transcript)|ensembl:ENST00000393900(transcript)|interpro:IPR002190(MAGE protein)|interpro:IPR021072|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|entrezgene/locuslink:4111(identity)	-	crc64:BFB0E6C5F93D3F07	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:PGCt+bqhn63vUVgS5IKrrOukXgg559292	rogid:3/Jxz2VsFOb67RWqWj3xbTrw3s49606	intact-crc:195F82B1F334D2E7|rigid:keh5VjBC/XE8jCKzGiHnaFBh6e4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P25377	uniprotkb:P38432	intact:EBI-2347652|uniprotkb:D6VRA5|ensemblfungi:YCR105W	intact:EBI-945751|uniprotkb:B2R931|ensembl:ENSP00000240316	psi-mi:adh7_yeast(display_long)|uniprotkb:ADH7(gene name)|psi-mi:ADH7(display_short)|uniprotkb:NADP-dependent alcohol dehydrogenase VII(gene name synonym)|uniprotkb:YCR105W(locus name)	psi-mi:coil_human(display_long)|uniprotkb:COIL(gene name)|psi-mi:COIL(display_short)|uniprotkb:CLN80(gene name synonym)|uniprotkb:p80-coilin(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11524555|imex:IM-24995-234	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010030.1|sgd:S000000702|dip:DIP-7661N|mint:P25377|ensemblfungi:YCR105W(gene)|ensemblfungi:YCR105W_mRNA(transcript)|go:"GO:0006066"(alcohol metabolic process)|go:"GO:0008106"("alcohol dehydrogenase (NADP+) activity")|go:"GO:0008270"(zinc ion binding)|go:"GO:0016616"(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|interpro:IPR002328(Alcohol dehydrogenase, zinc-containing, conserved site)|interpro:IPR011032(GroES-like)|interpro:IPR013149(Alcohol dehydrogenase, zinc-binding)|interpro:IPR013154(Alcohol dehydrogenase GroES-like)|interpro:IPR020843|interpro:IPR029752|interpro:IPR036291|sgd:YCR105W(identity)	refseq:NP_004636.1|dip:DIP-38503N|ensembl:ENSG00000121058(gene)|ensembl:ENST00000240316(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0015030"(Cajal body)|go:"GO:0016020"(membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0030619"(U1 snRNA binding)|go:"GO:0030620"(U2 snRNA binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR024822|interpro:IPR031722|mint:P38432|entrezgene/locuslink:8161(identity)	-	crc64:BFB0E6C5F93D3F07	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:PGCt+bqhn63vUVgS5IKrrOukXgg559292	rogid:hd5p6AbyA/GYNEeca99Mdb41qM09606	intact-crc:AB7E44C9FE27A4F7|rigid:f+UCxJGH8DarSYA0nEMYqaC7YRI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P25372	uniprotkb:Q9Y3Q8	intact:EBI-19616|uniprotkb:D6VR84|ensemblfungi:YCR083W	intact:EBI-739485|uniprotkb:A8MWR6|ensembl:ENSP00000300181|uniprotkb:A4D2C3|uniprotkb:D6W5V9	psi-mi:trx3_yeast(display_long)|uniprotkb:TRX3(gene name)|psi-mi:TRX3(display_short)|uniprotkb:YCR83W(orf name)|uniprotkb:YCR083W(locus name)	psi-mi:t22d4_human(display_long)|uniprotkb:TSC22D4(gene name)|psi-mi:TSC22D4(display_short)|uniprotkb:TILZ2(gene name synonym)|uniprotkb:TSC22-related-inducible leucine zipper protein 2(gene name synonym)|uniprotkb:Tsc-22-like protein THG-1(gene name synonym)|uniprotkb:THG1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11524523|imex:IM-24995-231	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR036249|refseq:NP_010006.1|sgd:S000000679|interpro:IPR017937|interpro:IPR013766(Thioredoxin domain)|rcsb pdb:2OE0|rcsb pdb:2OE1|rcsb pdb:2OE3|ensemblfungi:YCR083W(gene)|ensemblfungi:YCR083W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0015036"(disulfide oxidoreductase activity)|go:"GO:0034599"(cellular response to oxidative stress)|rcsb pdb:5YKW|sgd:YCR083W(identity)	ensembl:ENSG00000166925(gene)|ensembl:ENST00000300181(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006970"(response to osmotic stress)|interpro:IPR000580(TSC-22 / Dip / Bun)|interpro:IPR042553|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|refseq:NP_112197.1|refseq:NP_001289972.1|entrezgene/locuslink:81628(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:g0xjGf9GvJRl8iv2qoT5tOs7jXI559292	rogid:eL12cHY76zEPOXzT1HFKPSckS8Y9606	intact-crc:66099E146EF39FFB|rigid:YczFP5l/qUDh5ND1iOxBAW2Cp9w	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9NPC3	uniprotkb:P25375	intact:EBI-745269|ensembl:ENSP00000337396|ensembl:ENSP00000351810|ensembl:ENSP00000381226|ensembl:ENSP00000381229|ensembl:ENSP00000381235|ensembl:ENSP00000409896	intact:EBI-13932|uniprotkb:E9P942|uniprotkb:D6VQW0|ensemblfungi:YCL057W	psi-mi:cip1_human(display_long)|uniprotkb:Cyclin-B1-interacting protein 1(gene name synonym)|uniprotkb:Human enhancer of invasion 10(gene name synonym)|uniprotkb:CCNB1IP1(gene name)|psi-mi:CCNB1IP1(display_short)|uniprotkb:C14orf18(gene name synonym)|uniprotkb:HEI10(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase CCNB1IP1(gene name synonym)	psi-mi:prtd_yeast(display_long)|uniprotkb:PRD1(gene name)|psi-mi:PRD1(display_short)|uniprotkb:YCL057W(locus name)|uniprotkb:YCL57W(orf name)|uniprotkb:Protease D(gene name synonym)|uniprotkb:Proteinase yscD(gene name synonym)|uniprotkb:Oligopeptidase YSCD(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11524533|imex:IM-24995-232	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_067001.3|refseq:NP_878269.1|refseq:NP_878272.1|ensembl:ENSG00000100814(gene)|ensembl:ENST00000353689(transcript)|ensembl:ENST00000358932(transcript)|ensembl:ENST00000398160(transcript)|ensembl:ENST00000398163(transcript)|ensembl:ENST00000398169(transcript)|ensembl:ENST00000437553(transcript)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001825"(blastocyst formation)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0007286"(spermatid development)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051026"(chiasma assembly)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR042448|entrezgene/locuslink:57820(identity)	refseq:NP_009874.1|sgd:S000000562|ensemblfungi:YCL057W(gene)|ensemblfungi:YCL057W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006508"(proteolysis)|go:"GO:0006518"(peptide metabolic process)|go:"GO:0046872"(metal ion binding)|interpro:IPR001567(Peptidase M3A and M3B, thimet/oligopeptidase F)|interpro:IPR024077|interpro:IPR024079|interpro:IPR024080|reactome:R-SCE-983168|mint:P25375|dip:DIP-4938N|sgd:YCL057W(identity)	-	-	crc64:340910B7FDAFBE37	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:UyF392Md+IuOz5wp9kW2Pjr2ZzY9606	rogid:WXFCl27lNmdlkUaDqmVZl0u4bGg559292	intact-crc:E90942CCFC83513C|rigid:81gO47TC1Ngvuv+dQnrkjbeuJPc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O76083-2	uniprotkb:P25377	intact:EBI-11524542|ensembl:ENSP00000335242	intact:EBI-2347652|uniprotkb:D6VRA5|ensemblfungi:YCR105W	psi-mi:o76083-2(display_long)|uniprotkb:PDE9A(gene name)|psi-mi:PDE9A(display_short)	psi-mi:adh7_yeast(display_long)|uniprotkb:ADH7(gene name)|psi-mi:ADH7(display_short)|uniprotkb:NADP-dependent alcohol dehydrogenase VII(gene name synonym)|uniprotkb:YCR105W(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11524546|imex:IM-24995-233	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-742764(isoform-parent)|ensembl:ENSG00000160191(gene)|ensembl:ENST00000335512(transcript)|uniprotkb:O76083-2(isoform-parent)|entrezgene/locuslink:5152(identity)	refseq:NP_010030.1|sgd:S000000702|dip:DIP-7661N|mint:P25377|ensemblfungi:YCR105W(gene)|ensemblfungi:YCR105W_mRNA(transcript)|go:"GO:0006066"(alcohol metabolic process)|go:"GO:0008106"("alcohol dehydrogenase (NADP+) activity")|go:"GO:0008270"(zinc ion binding)|go:"GO:0016616"(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|interpro:IPR002328(Alcohol dehydrogenase, zinc-containing, conserved site)|interpro:IPR011032(GroES-like)|interpro:IPR013149(Alcohol dehydrogenase, zinc-binding)|interpro:IPR013154(Alcohol dehydrogenase GroES-like)|interpro:IPR020843|interpro:IPR029752|interpro:IPR036291|sgd:YCR105W(identity)	-	-	crc64:BFB0E6C5F93D3F07	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:nTzgeYGOwTM/7VJUgxSnlnDiCFo9606	rogid:PGCt+bqhn63vUVgS5IKrrOukXgg559292	intact-crc:54AB9CB1C9D1DE24|rigid:JbiTJHJ1iOe/jhMhIOce+Tu0vtY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P25515	uniprotkb:P63279	intact:EBI-7739233|ensemblfungi:YEL027W|intact:MINT-1353979|uniprotkb:D3DLM1	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	psi-mi:vatl1_yeast(display_long)|uniprotkb:VMA3(gene name)|psi-mi:VMA3(display_short)|uniprotkb:CLS7(gene name synonym)|uniprotkb:CUP5(gene name synonym)|uniprotkb:GEF2(gene name synonym)|uniprotkb:YEL027W(locus name)|uniprotkb:Vacuolar proton pump c subunit(gene name synonym)|uniprotkb:V-ATPase 16 kDa proteolipid subunit 1(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor 2(gene name synonym)	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11524613|imex:IM-24995-240	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR002379(ATPase, F0/V0 complex, subunit C)|interpro:IPR011555(ATPase, V0 complex, proteolipid subunit C, eukaryotic)|interpro:IPR035921|rcsb pdb:3J9T|rcsb pdb:3J9U|rcsb pdb:3J9V|rcsb pdb:5TJ5|rcsb pdb:5VOX|rcsb pdb:5VOY|rcsb pdb:5VOZ|rcsb pdb:6C6L|rcsb pdb:6M0R|rcsb pdb:6M0S|rcsb pdb:6O7T|rcsb pdb:6O7U|rcsb pdb:6O7V|rcsb pdb:6O7W|rcsb pdb:6O7X|rcsb pdb:6PE4|rcsb pdb:6PE5|reactome:R-SCE-1222556|reactome:R-SCE-6798695|reactome:R-SCE-77387|reactome:R-SCE-917977|reactome:R-SCE-9639288|ensemblfungi:YEL027W(gene)|ensemblfungi:YEL027W_mRNA(transcript)|go:"GO:0000220"(vacuolar proton-transporting V-type ATPase, V0 domain)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006878"(cellular copper ion homeostasis)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0006897"(endocytosis)|go:"GO:0007033"(vacuole organization)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR000245(ATPase, V0 complex, proteolipid subunit C,)|sgd:S000000753|mint:P25515|refseq:NP_010887.3|dip:DIP-8123N|sgd:YEL027W(identity)	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N|entrezgene/locuslink:7329(identity)	-	crc64:FB8A142FFA1FA964|comment:mint|function:Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. It is an electrogenic proton pump that generates a proton motive force of 180 mv, inside positive and acidic, in the vacuolar membrane vesicles	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:MAXfIOCwZyeV4Vy1T0eKqIbS4ZQ559292	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	intact-crc:F848EED2BC731EB3|rigid:+lYpw9WhGGP2lQbI4FItuk7aeGw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P25453	uniprotkb:P63279	intact:EBI-5955|uniprotkb:D3DM88|ensemblfungi:YER179W	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	psi-mi:dmc1_yeast(display_long)|uniprotkb:YER179W(locus name)|uniprotkb:DMC1(gene name)|psi-mi:DMC1(display_short)|uniprotkb:ISC2(gene name synonym)	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11524604|imex:IM-24995-239	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011106.1|sgd:S000000981|dip:DIP-110N|mint:P25453|ensemblfungi:YER179W(gene)|ensemblfungi:YER179W_mRNA(transcript)|go:"GO:0000150"(DNA strand exchange activity)|go:"GO:0000709"(meiotic joint molecule formation)|go:"GO:0000730"(DNA recombinase assembly)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006312"(mitotic recombination)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0030435"(sporulation resulting in formation of a cellular spore)|go:"GO:0042030"(ATPase inhibitor activity)|go:"GO:0042148"(strand invasion)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070192"(chromosome organization involved in meiotic cell cycle)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010995(DNA repair Rad51/transcription factor NusA, alpha-helical)|interpro:IPR011940(Meiotic recombinase Dmc1)|interpro:IPR013632(Rad51, C-terminal)|interpro:IPR016467(DNA repair and recombination, RecA-like)|interpro:IPR020587|interpro:IPR020588|interpro:IPR027417|interpro:IPR033925|sgd:YER179W(identity)	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N|entrezgene/locuslink:7329(identity)	-	crc64:00B0503D7FAF5CB3	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:tbn7/STS08gIJBzfUmIz/yPmBJ8559292	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	intact-crc:3E7DC913AC4420AA|rigid:3bEIEs4jkQOFMJU/UEvB+mRwNfU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P25377	uniprotkb:P61371	intact:EBI-2347652|uniprotkb:D6VRA5|ensemblfungi:YCR105W	intact:EBI-3906896|uniprotkb:P47894|uniprotkb:P20663|ensembl:ENSP00000230658	psi-mi:adh7_yeast(display_long)|uniprotkb:ADH7(gene name)|psi-mi:ADH7(display_short)|uniprotkb:NADP-dependent alcohol dehydrogenase VII(gene name synonym)|uniprotkb:YCR105W(locus name)	psi-mi:isl1_human(display_long)|uniprotkb:ISL1(gene name)|psi-mi:ISL1(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11524573|imex:IM-24995-236	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010030.1|sgd:S000000702|dip:DIP-7661N|mint:P25377|ensemblfungi:YCR105W(gene)|ensemblfungi:YCR105W_mRNA(transcript)|go:"GO:0006066"(alcohol metabolic process)|go:"GO:0008106"("alcohol dehydrogenase (NADP+) activity")|go:"GO:0008270"(zinc ion binding)|go:"GO:0016616"(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|interpro:IPR002328(Alcohol dehydrogenase, zinc-containing, conserved site)|interpro:IPR011032(GroES-like)|interpro:IPR013149(Alcohol dehydrogenase, zinc-binding)|interpro:IPR013154(Alcohol dehydrogenase GroES-like)|interpro:IPR020843|interpro:IPR029752|interpro:IPR036291|sgd:YCR105W(identity)	refseq:NP_002193.2|ensembl:ENSP00000230658|ensembl:ENSG00000016082(gene)|ensembl:ENST00000230658(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001755"(neural crest cell migration)|go:"GO:0003139"(secondary heart field specification)|go:"GO:0003148"(outflow tract septum morphogenesis)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0003203"(endocardial cushion morphogenesis)|go:"GO:0003215"(cardiac right ventricle morphogenesis)|go:"GO:0003266"(regulation of secondary heart field cardioblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007409"(axonogenesis)|go:"GO:0007507"(heart development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010575"(positive regulation of vascular endothelial growth factor production)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0021520"(spinal cord motor neuron cell fate specification)|go:"GO:0021522"(spinal cord motor neuron differentiation)|go:"GO:0021524"(visceral motor neuron differentiation)|go:"GO:0021559"(trigeminal nerve development)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0031016"(pancreas development)|go:"GO:0031103"(axon regeneration)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0031290"(retinal ganglion cell axon guidance)|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048665"(neuron fate specification)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0048880"(sensory system development)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0048936"(peripheral nervous system neuron axonogenesis)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0060037"(pharyngeal system development)|go:"GO:0060379"(cardiac muscle cell myoblast differentiation)|go:"GO:0060384"(innervation)|go:"GO:0060413"(atrial septum morphogenesis)|go:"GO:0060913"(cardiac cell fate determination)|go:"GO:0060931"(sinoatrial node cell development)|go:"GO:0032725"(positive regulation of granulocyte macrophage colony-stimulating factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032730"(positive regulation of interleukin-1 alpha production)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0071657"(positive regulation of granulocyte colony-stimulating factor production)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1901258"(positive regulation of macrophage colony-stimulating factor production)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001356(Homeobox)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|mint:P61371|reactome:R-HSA-400511|reactome:R-HSA-9010553|entrezgene/locuslink:3670(identity)	-	crc64:BFB0E6C5F93D3F07	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:PGCt+bqhn63vUVgS5IKrrOukXgg559292	rogid:1eir7wLzkoqlwl4AfQuBtjjiyd09606	intact-crc:331CB78BBB059EA8|rigid:EdWNISKdl+iTNjPZeQZyVi1XzTo	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8WXE1-3	uniprotkb:P25377	intact:EBI-11524582|ensembl:ENSP00000400930	intact:EBI-2347652|uniprotkb:D6VRA5|ensemblfungi:YCR105W	psi-mi:q8wxe1-3(display_long)|uniprotkb:ATRIP(gene name)|psi-mi:ATRIP(display_short)|uniprotkb:AGS1(gene name synonym)|uniprotkb:ATM and Rad3-related-interacting protein(gene name synonym)	psi-mi:adh7_yeast(display_long)|uniprotkb:ADH7(gene name)|psi-mi:ADH7(display_short)|uniprotkb:NADP-dependent alcohol dehydrogenase VII(gene name synonym)|uniprotkb:YCR105W(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11524586|imex:IM-24995-237	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-747353(isoform-parent)|ensembl:ENSG00000164053(gene)|ensembl:ENST00000412052(transcript)|entrezgene/locuslink:84126(identity)	refseq:NP_010030.1|sgd:S000000702|dip:DIP-7661N|mint:P25377|ensemblfungi:YCR105W(gene)|ensemblfungi:YCR105W_mRNA(transcript)|go:"GO:0006066"(alcohol metabolic process)|go:"GO:0008106"("alcohol dehydrogenase (NADP+) activity")|go:"GO:0008270"(zinc ion binding)|go:"GO:0016616"(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|interpro:IPR002328(Alcohol dehydrogenase, zinc-containing, conserved site)|interpro:IPR011032(GroES-like)|interpro:IPR013149(Alcohol dehydrogenase, zinc-binding)|interpro:IPR013154(Alcohol dehydrogenase GroES-like)|interpro:IPR020843|interpro:IPR029752|interpro:IPR036291|sgd:YCR105W(identity)	-	isoform-comment:No experimental confirmation available.	crc64:BFB0E6C5F93D3F07	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:NKCjy1jGZEySEhUOf8rJ6h9pyxY9606	rogid:PGCt+bqhn63vUVgS5IKrrOukXgg559292	intact-crc:3FDA5EA8D5950682|rigid:QIrliXieSc8Ux2A78vwZ+kw2xIU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P25385	uniprotkb:Q12846	intact:EBI-3735|uniprotkb:D6VY78|ensemblfungi:YLR078C	intact:EBI-744942|uniprotkb:Q15525|ensembl:ENSP00000317714|uniprotkb:Q6FHE8|uniprotkb:A8MXY0	psi-mi:bos1_yeast(display_long)|uniprotkb:BOS1(gene name)|psi-mi:BOS1(display_short)|uniprotkb:YLR078C(locus name)|uniprotkb:L9449.9(orf name)|uniprotkb:Bet one suppressor 1(gene name synonym)	psi-mi:stx4_human(display_long)|uniprotkb:Renal carcinoma antigen NY-REN-31(gene name synonym)|uniprotkb:STX4(gene name)|psi-mi:STX4(display_short)|uniprotkb:STX4A(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11524595|imex:IM-24995-238	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013179.1|sgd:S000004068|reactome:R-SCE-204005|reactome:R-SCE-5694530|reactome:R-SCE-6807878|dip:DIP-2020N|ensemblfungi:YLR078C(gene)|ensemblfungi:YLR078C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0006906"(vesicle fusion)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0031902"(late endosome membrane)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0048280"(vesicle fusion with Golgi apparatus)|interpro:IPR027027|sgd:YLR078C(identity)	ensembl:ENSG00000103496(gene)|refseq:NP_004595.2|ensembl:ENST00000313843(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0000322"(storage vacuole)|go:"GO:0002639"(positive regulation of immunoglobulin production)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005768"(endosome)|go:"GO:0005773"(vacuole)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006887"(exocytosis)|go:"GO:0006906"(vesicle fusion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016230"(sphingomyelin phosphodiesterase activator activity)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0032589"(neuron projection membrane)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035493"(SNARE complex assembly)|go:"GO:0035749"(myelin sheath adaxonal region)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0036477"(somatodendritic compartment)|go:"GO:0042581"(specific granule)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043197"(dendritic spine)|go:"GO:0043219"(lateral loop)|go:"GO:0043311"(positive regulation of eosinophil degranulation)|go:"GO:0045202"(synapse)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0048278"(vesicle docking)|go:"GO:0048284"(organelle fusion)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048787"(presynaptic active zone membrane)|go:"GO:0050921"(positive regulation of chemotaxis)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1902041"(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1903575"(cornified envelope assembly)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|reactome:R-HSA-114516|reactome:R-HSA-1236974|reactome:R-HSA-1445148|reactome:R-HSA-199992|reactome:R-HSA-449836|interpro:IPR006011(Syntaxin, N-terminal)|refseq:NP_001259025.1|entrezgene/locuslink:6810(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Rwf+Olm3mXTGhh/KZUgtVel+wzc559292	rogid:NvOLGIGe/XO2aDPSpdPzrtKniZY9606	intact-crc:A5E0CD1813B4A7E6|rigid:h0WCNB/fcQEBEqbIlGx+UKyw0L8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P25611	uniprotkb:P63279	intact:EBI-22052|uniprotkb:D6VRA6|ensemblfungi:YCR106W	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	psi-mi:rds1_yeast(display_long)|uniprotkb:YCR106W(locus name)|uniprotkb:RDS1(gene name)|psi-mi:RDS1(display_short)	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11524667|imex:IM-24995-246	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010031.1|sgd:S000000703|dip:DIP-2014N|ensemblfungi:YCR106W(gene)|ensemblfungi:YCR106W_mRNA(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009410"(response to xenobiotic stimulus)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR001138(Fungal transcriptional regulatory protein, N-terminal)|interpro:IPR036864|mint:P25611|sgd:YCR106W(identity)	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N|entrezgene/locuslink:7329(identity)	-	crc64:7DF91D86AF08E4E3	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:1um+FEn46D2/f4P58Zo/rIQSEZU559292	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	intact-crc:939420C595E7B1EE|rigid:tbMuMDUh0kZb/AIj+CkKwP4JPyw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96BR9	uniprotkb:P25586	intact:EBI-742740|uniprotkb:Q8IUL5|uniprotkb:Q8IWR9|uniprotkb:Q8N2Y5|uniprotkb:Q96BX0|ensembl:ENSP00000362609	intact:EBI-21773|uniprotkb:D6VQV7|ensemblfungi:YCL059C	psi-mi:zbt8a_human(display_long)|uniprotkb:ZBTB8A(gene name)|psi-mi:ZBTB8A(display_short)|uniprotkb:BOZF1(gene name synonym)|uniprotkb:BTB/POZ and zinc-finger domain-containing factor(gene name synonym)|uniprotkb:BTB/POZ and zinc-finger domains factor on chromosome 1(gene name synonym)	psi-mi:krr1_yeast(display_long)|uniprotkb:KRR1(gene name)|psi-mi:KRR1(display_short)|uniprotkb:KRR-R motif-containing protein 1(gene name synonym)|uniprotkb:Ribosomal RNA assembly protein KRR1(gene name synonym)|uniprotkb:YCL59C(orf name)|uniprotkb:YCL059C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11524658|imex:IM-24995-245	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000160062(gene)|ensembl:ENST00000373510(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|refseq:NP_001035531.2|refseq:NP_001278425.1|entrezgene/locuslink:653121(identity)	refseq:NP_009872.1|sgd:S000000564|mint:P25586|dip:DIP-1408N|ensemblfungi:YCL059C_mRNA(transcript)|go:"GO:0000447"("endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0030686"(90S preribosome)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0032040"(small-subunit processome)|go:"GO:0042274"(ribosomal small subunit biogenesis)|interpro:IPR004087(K Homology)|interpro:IPR024166|interpro:IPR036612|interpro:IPR041174|rcsb pdb:4QMF|rcsb pdb:5WLC|rcsb pdb:5WYJ|rcsb pdb:5WYK|rcsb pdb:6KE6|rcsb pdb:6LQP|rcsb pdb:6LQQ|rcsb pdb:6LQU|rcsb pdb:6ZQA|rcsb pdb:6ZQB|rcsb pdb:6ZQC|rcsb pdb:7AJT|reactome:R-SCE-6791226|ensemblfungi:YCL059C(gene)|sgd:YCL059C(identity)	-	-	crc64:7A7F964E2C7FD056	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:tsrPT2tHvuBryODKgRXnceXz9s09606	rogid:wveCX/DmVjCNLOIejb/nWbrbX3o559292	intact-crc:EB062B106A14950B|rigid:14DucJA9ZMk13aDdze4XbiwfpgU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P25566	uniprotkb:Q12800	intact:EBI-21713|uniprotkb:D6VQY2|ensemblfungi:YCL033C	intact:EBI-717422|uniprotkb:Q12801|uniprotkb:Q9UD77|uniprotkb:A8K5E9|uniprotkb:Q9UD75|ensembl:ENSP00000257915	psi-mi:mxr2_yeast(display_long)|uniprotkb:YCL033C(locus name)|uniprotkb:YCL33C(orf name)|uniprotkb:MXR2(gene name)|psi-mi:MXR2(display_short)|uniprotkb:MSRB(gene name synonym)	psi-mi:tfcp2_human(display_long)|uniprotkb:Transcription factor LSF(gene name synonym)|uniprotkb:SAA3 enhancer factor(gene name synonym)|uniprotkb:TFCP2(gene name)|psi-mi:TFCP2(display_short)|uniprotkb:LSF(gene name synonym)|uniprotkb:SEF(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11524622|imex:IM-24995-241	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009897.1|sgd:S000000538|dip:DIP-4861N|ensemblfungi:YCL033C(gene)|ensemblfungi:YCL033C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0030091"(protein repair)|go:"GO:0033743"("peptide-methionine (R)-S-oxide reductase activity")|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0046872"(metal ion binding)|interpro:IPR002579(Methionine sulphoxide reductase B)|interpro:IPR011057(Mss4-like)|interpro:IPR028427|sgd:YCL033C(identity)	refseq:NP_001166923.1|refseq:NP_001166924.1|refseq:NP_005644.2|ensembl:ENSG00000135457(gene)|ensembl:ENST00000257915(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR007604(CP2 transcription factor)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR037599|interpro:IPR041418|mint:Q12800|entrezgene/locuslink:7024(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:iqa3p6vw9Ah3pxugESw1TdFd6bU559292	rogid:M7mQ08NDYxuawmUEKRgjSdIr+Og9606	intact-crc:CB640141AE84F500|rigid:T81VuNmA06E5rN2a8yPQld5qp7s	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q93062-3	uniprotkb:P25566	intact:EBI-740343|ensembl:ENSP00000340176	intact:EBI-21713|uniprotkb:D6VQY2|ensemblfungi:YCL033C	psi-mi:q93062-3(display_long)|uniprotkb:RBPMS(gene name)|psi-mi:RBPMS(display_short)|uniprotkb:HERMES(gene name synonym)|uniprotkb:Heart and RRM expressed sequence(gene name synonym)	psi-mi:mxr2_yeast(display_long)|uniprotkb:YCL033C(locus name)|uniprotkb:YCL33C(orf name)|uniprotkb:MXR2(gene name)|psi-mi:MXR2(display_short)|uniprotkb:MSRB(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11524640|imex:IM-24995-243	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-740322(rbpms_human)|uniprotkb:Q93062-3(isoform-parent)|ensembl:ENSG00000157110(gene)|ensembl:ENST00000339877(transcript)|entrezgene/locuslink:11030(identity)	refseq:NP_009897.1|sgd:S000000538|dip:DIP-4861N|ensemblfungi:YCL033C(gene)|ensemblfungi:YCL033C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0030091"(protein repair)|go:"GO:0033743"("peptide-methionine (R)-S-oxide reductase activity")|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0046872"(metal ion binding)|interpro:IPR002579(Methionine sulphoxide reductase B)|interpro:IPR011057(Mss4-like)|interpro:IPR028427|sgd:YCL033C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:nlPMQAJoKEbPYBwsL3xodmCKd7c9606	rogid:iqa3p6vw9Ah3pxugESw1TdFd6bU559292	intact-crc:855F1DA11085B4E6|rigid:tiFI/MCyj+mCRyIppJ+RuLF762E	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8N9N5-2	uniprotkb:P25566	intact:EBI-11524452|ensembl:ENSP00000347125	intact:EBI-21713|uniprotkb:D6VQY2|ensemblfungi:YCL033C	psi-mi:q8n9n5-2(display_long)|uniprotkb:BANP(gene name)|psi-mi:BANP(display_short)|uniprotkb:BEN domain-containing protein 1(gene name synonym)|uniprotkb:BEND1(gene name synonym)|uniprotkb:Btg3-associated nuclear protein(gene name synonym)|uniprotkb:SMAR1(gene name synonym)|uniprotkb:Scaffold/matrix-associated region-1-binding protein(gene name synonym)	psi-mi:mxr2_yeast(display_long)|uniprotkb:YCL033C(locus name)|uniprotkb:YCL33C(orf name)|uniprotkb:MXR2(gene name)|psi-mi:MXR2(display_short)|uniprotkb:MSRB(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11524631|imex:IM-24995-242	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000172530(gene)|ensembl:ENST00000355022(transcript)|intact:EBI-744695(isoform-parent)|uniprotkb:Q8N9N5-2(isoform-parent)|entrezgene/locuslink:54971(identity)	refseq:NP_009897.1|sgd:S000000538|dip:DIP-4861N|ensemblfungi:YCL033C(gene)|ensemblfungi:YCL033C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0030091"(protein repair)|go:"GO:0033743"("peptide-methionine (R)-S-oxide reductase activity")|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0046872"(metal ion binding)|interpro:IPR002579(Methionine sulphoxide reductase B)|interpro:IPR011057(Mss4-like)|interpro:IPR028427|sgd:YCL033C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:ESe6iCAhvq+i57fQHz3rGyg6UOo9606	rogid:iqa3p6vw9Ah3pxugESw1TdFd6bU559292	intact-crc:5631CD9518544AAD|rigid:QDKId1BrMktzR5nKsR1jWENa2Lk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O95751	uniprotkb:P25586	intact:EBI-740738|ensembl:ENSP00000359557|uniprotkb:Q6IAR6	intact:EBI-21773|uniprotkb:D6VQV7|ensemblfungi:YCL059C	psi-mi:ldoc1_human(display_long)|uniprotkb:Leucine zipper protein down-regulated in cancer cells(gene name synonym)|uniprotkb:LDOC1(gene name)|psi-mi:LDOC1(display_short)|uniprotkb:BCUR1(gene name synonym)	psi-mi:krr1_yeast(display_long)|uniprotkb:KRR1(gene name)|psi-mi:KRR1(display_short)|uniprotkb:KRR-R motif-containing protein 1(gene name synonym)|uniprotkb:Ribosomal RNA assembly protein KRR1(gene name synonym)|uniprotkb:YCL59C(orf name)|uniprotkb:YCL059C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11524649|imex:IM-24995-244	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_036449.1|ensembl:ENSG00000182195(gene)|ensembl:ENST00000370526(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071225"(cellular response to muramyl dipeptide)|interpro:IPR032549|interpro:IPR032567|entrezgene/locuslink:23641(identity)	refseq:NP_009872.1|sgd:S000000564|mint:P25586|dip:DIP-1408N|ensemblfungi:YCL059C_mRNA(transcript)|go:"GO:0000447"("endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0030686"(90S preribosome)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0032040"(small-subunit processome)|go:"GO:0042274"(ribosomal small subunit biogenesis)|interpro:IPR004087(K Homology)|interpro:IPR024166|interpro:IPR036612|interpro:IPR041174|rcsb pdb:4QMF|rcsb pdb:5WLC|rcsb pdb:5WYJ|rcsb pdb:5WYK|rcsb pdb:6KE6|rcsb pdb:6LQP|rcsb pdb:6LQQ|rcsb pdb:6LQU|rcsb pdb:6ZQA|rcsb pdb:6ZQB|rcsb pdb:6ZQC|rcsb pdb:7AJT|reactome:R-SCE-6791226|ensemblfungi:YCL059C(gene)|sgd:YCL059C(identity)	-	-	crc64:7A7F964E2C7FD056	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Ediu0oNiZ/+YVY8l3fNdgP5A+v09606	rogid:wveCX/DmVjCNLOIejb/nWbrbX3o559292	intact-crc:66653C5DB5C1B2F6|rigid:Fb8dyjYSS1xcF+wKlzG0bFqw6nQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O00635	uniprotkb:P25635	intact:EBI-2130415|uniprotkb:B2R862|ensembl:ENSP00000349596	intact:EBI-14332|uniprotkb:P25633|uniprotkb:P25636|uniprotkb:D6VR63|ensemblfungi:YCR057C	psi-mi:tri38_human(display_long)|uniprotkb:TRIM38(gene name)|psi-mi:TRIM38(display_short)|uniprotkb:RNF15(gene name synonym)|uniprotkb:RORET(gene name synonym)|uniprotkb:RING finger protein 15(gene name synonym)|uniprotkb:Zinc finger protein RoRet(gene name synonym)|uniprotkb:Tripartite motif-containing protein 38(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM38(gene name synonym)	psi-mi:pwp2_yeast(display_long)|uniprotkb:PWP2(gene name)|psi-mi:PWP2(display_short)|uniprotkb:UTP1(gene name synonym)|uniprotkb:YCR057C(locus name)|uniprotkb:YCR55C/YCR57C/YCR58C(orf name)|uniprotkb:U3 small nucleolar RNA-associated protein 1(gene name synonym)|uniprotkb:U three protein 1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11524703|imex:IM-24995-250	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006346.1|refseq:XP_005248856.1|refseq:XP_005248857.1|ensembl:ENSG00000112343(gene)|ensembl:ENST00000357085(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046598"(positive regulation of viral entry into host cell)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR035790|interpro:IPR043136|reactome:R-HSA-877300|entrezgene/locuslink:10475(identity)	go:"GO:0000920"(septum digestion after cytokinesis)|go:"GO:0003729"(mRNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030686"(90S preribosome)|go:"GO:0032040"(small-subunit processome)|go:"GO:0034388"(Pwp2p-containing subcomplex of 90S preribosome)|interpro:IPR001680(WD40 repeat)|interpro:IPR007148(Small-subunit processome, Utp12)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR027145|interpro:IPR036322|rcsb pdb:5I2T|rcsb pdb:5WLC|rcsb pdb:5WYJ|ensemblfungi:YCR057C(gene)|ensemblfungi:YCR057C_mRNA(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0000447"("endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|rcsb pdb:5WYK|go:"GO:0000472"("endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000480"("endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|rcsb pdb:6KE6|rcsb pdb:6LQP|rcsb pdb:6LQQ|rcsb pdb:6LQR|rcsb pdb:6LQS|rcsb pdb:6LQT|rcsb pdb:6LQU|rcsb pdb:6LQV|rcsb pdb:6ND4|rcsb pdb:6ZQA|rcsb pdb:6ZQB|rcsb pdb:6ZQC|rcsb pdb:6ZQD|rcsb pdb:6ZQE|rcsb pdb:6ZQF|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-6791226|refseq:NP_009984.1|sgd:S000000653|mint:P25635|dip:DIP-1868N|sgd:YCR057C(identity)	-	-	crc64:CBEE4720F81378B6	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Zh4X/6v/qKZlDkMV6hhn7OsvPnQ9606	rogid:3JKhaE50yPlCymnkEC14JB9atNY559292	intact-crc:830FC742E815B091|rigid:5UniEi26OZCrhkjs49PI/+pPHEk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96BA8	uniprotkb:P25619	intact:EBI-6942903|ensembl:ENSP00000481956|intact:MINT-268046|intact:MINT-8162577|uniprotkb:Q8N2D5|uniprotkb:Q96CP0	intact:EBI-8563|uniprotkb:Q04556|uniprotkb:D6VR31|ensemblfungi:YCR021C	psi-mi:cr3l1_human(display_long)|uniprotkb:CREB3L1(gene name)|psi-mi:CREB3L1(display_short)|uniprotkb:OASIS(gene name synonym)|uniprotkb:PSEC0238(orf name)|uniprotkb:Old astrocyte specifically-induced substance(gene name synonym)	psi-mi:hsp30_yeast(display_long)|uniprotkb:YCR21C(orf name)|uniprotkb:YCR021C(locus name)|uniprotkb:HSP30(gene name)|psi-mi:HSP30(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11524676|imex:IM-24995-247	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157613(gene)|ensembl:ENST00000621158(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0070278"(extracellular matrix constituent secretion)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029805|mint:Q96BA8|reactome:R-HSA-8874211|refseq:NP_443086.1|entrezgene/locuslink:90993(identity)	refseq:NP_009950.1|sgd:S000000615|mint:P25619|dip:DIP-4586N|ensemblfungi:YCR021C(gene)|ensemblfungi:YCR021C_mRNA(transcript)|go:"GO:0005216"(ion channel activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0034605"(cellular response to heat)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0071470"(cellular response to osmotic stress)|interpro:IPR001425(Rhodopsin, bacterial)|interpro:IPR043476|sgd:YCR021C(identity)	-	comment:mint|function:"Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE"	crc64:260474A481D29AC5	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:sMWUFmBeBBCO+T0Y2CuB/un1lBg9606	rogid:hkFai3t0xeh5wGaj/RAYUfPwoPw559292	intact-crc:10F4394B5743A348|rigid:67qn36GAPcksjVg01uLfF9E88fk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O14874	uniprotkb:P25631	intact:EBI-1046765|uniprotkb:Q96IN5|uniprotkb:Q6FGL4|intact:EBI-1210327|uniprotkb:A8MY43|uniprotkb:Q96G95|ensembl:ENSP00000219794|ensembl:ENSP00000378405	intact:EBI-2347265|uniprotkb:D6VR59|ensemblfungi:YCR051W	psi-mi:bckd_human(display_long)|uniprotkb:Branched-chain alpha-ketoacid dehydrogenase kinase(gene name synonym)|uniprotkb:BCKDK(gene name)|psi-mi:BCKDK(display_short)	psi-mi:ycu1_yeast(display_long)|uniprotkb:YCR51W(orf name)|uniprotkb:YCR051W(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11524685|imex:IM-24995-248	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005872.2|go:"GO:0005947"(mitochondrial alpha-ketoglutarate dehydrogenase complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006550"(isoleucine catabolic process)|go:"GO:0006552"(leucine catabolic process)|go:"GO:0006574"(valine catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009063"(cellular amino acid catabolic process)|go:"GO:0009083"(branched-chain amino acid catabolic process)|go:"GO:0010906"(regulation of glucose metabolic process)|go:"GO:0016301"(kinase activity)|go:"GO:0016310"(phosphorylation)|go:"GO:0045763"(negative regulation of cellular amino acid metabolic process)|go:"GO:0047323"("[3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring)] kinase activity")|interpro:IPR003594(ATP-binding region, ATPase-like)|refseq:NP_001116429.1|refseq:NP_001258855.1|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR018955|go:"GO:0005759"(mitochondrial matrix)|interpro:IPR036784|interpro:IPR036890|interpro:IPR039028|mint:O14874|reactome:R-HSA-70895|ensembl:ENSG00000103507(gene)|ensembl:ENST00000219794(transcript)|ensembl:ENST00000394951(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004740"("pyruvate dehydrogenase (acetyl-transferring) kinase activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|entrezgene/locuslink:10295(identity)	refseq:NP_009980.1|sgd:S000000647|interpro:IPR002110(Ankyrin)|interpro:IPR036770|ensemblfungi:YCR051W(gene)|ensemblfungi:YCR051W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|sgd:YCR051W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:0hiSb7/qtSPoHt/cmLnUo7Gq6OI9606	rogid:xSvXYNOUhBZjJgwGzwJ+muPq8tU559292	intact-crc:FA9C5FF3BD764223|rigid:yZ1XK5JunV7csCewqliY0rXO2FY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P25631	uniprotkb:Q8TBB1	intact:EBI-2347265|uniprotkb:D6VR59|ensemblfungi:YCR051W	intact:EBI-739832|uniprotkb:Q4W5K7|uniprotkb:Q8N4C2|uniprotkb:Q96MJ7|uniprotkb:Q9BY20|ensembl:ENSP00000263925	psi-mi:ycu1_yeast(display_long)|uniprotkb:YCR51W(orf name)|uniprotkb:YCR051W(locus name)	psi-mi:lnx1_human(display_long)|uniprotkb:LNX1(gene name)|psi-mi:LNX1(display_short)|uniprotkb:LNX(gene name synonym)|uniprotkb:Numb-binding protein 1(gene name synonym)|uniprotkb:Ligand of Numb-protein X 1(gene name synonym)|uniprotkb:PDZ domain-containing RING finger protein 2(gene name synonym)|uniprotkb:PDZRN2(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase LNX(gene name synonym)|uniprotkb:UNQ574/PRO1136(orf name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11524694|imex:IM-24995-249	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009980.1|sgd:S000000647|interpro:IPR002110(Ankyrin)|interpro:IPR036770|ensemblfungi:YCR051W(gene)|ensemblfungi:YCR051W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|sgd:YCR051W(identity)	refseq:NP_001119800.1|refseq:NP_116011.2|refseq:XP_005265842.1|refseq:XP_016864265.1|ensembl:ENSG00000072201(gene)|ensembl:ENST00000263925(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR036034|mint:Q8TBB1|rcsb pdb:3B76|rcsb pdb:5H7R|rcsb pdb:5H7S|reactome:R-HSA-983168|entrezgene/locuslink:84708(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:xSvXYNOUhBZjJgwGzwJ+muPq8tU559292	rogid:tWvePnVxh9yxWl8nQd3KZhCSKKo9606	intact-crc:55A471C2541ACF6A|rigid:/Yna5fluuFNb50rujtP1z/VIRlM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P25641	uniprotkb:Q96HH9	intact:EBI-375693|uniprotkb:Q8NIL6|uniprotkb:D6VR71|ensemblfungi:YCR068W	intact:EBI-2832937|uniprotkb:Q9H753|uniprotkb:D3DSZ3|uniprotkb:B7Z1F2|uniprotkb:B7Z3R1|uniprotkb:B7Z6D8|uniprotkb:B7Z8T2|ensembl:ENSP00000285689	psi-mi:atg15_yeast(display_long)|uniprotkb:ATG15(gene name)|psi-mi:ATG15(display_short)|uniprotkb:AUT5(gene name synonym)|uniprotkb:CVT17(gene name synonym)|uniprotkb:YCR068W(locus name)|uniprotkb:YCR68W(orf name)|uniprotkb:Autophagy-related protein 15(gene name synonym)|uniprotkb:Cytoplasm to vacuole targeting protein 17(gene name synonym)	psi-mi:grm2b_human(display_long)|uniprotkb:GRAMD2B(gene name)|psi-mi:GRAMD2B(display_short)|uniprotkb:GRAMD3(gene name synonym)|uniprotkb:HCV NS3-transactivated protein 2(gene name synonym)|uniprotkb:NS3TP2(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11524750|imex:IM-24995-255	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YCR068W_mRNA(transcript)|go:"GO:0000425"(pexophagy)|go:"GO:0004620"(phospholipase activity)|go:"GO:0004806"(triglyceride lipase activity)|go:"GO:0005775"(vacuolar lumen)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006624"(vacuolar protein processing)|go:"GO:0006660"(phosphatidylserine catabolic process)|go:"GO:0006914"(autophagy)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0030397"(membrane disassembly)|go:"GO:0032585"(multivesicular body membrane)|go:"GO:0034496"(multivesicular body membrane disassembly)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0046461"(neutral lipid catabolic process)|interpro:IPR002921(Lipase, class 3)|interpro:IPR029058|ensemblfungi:YCR068W(gene)|refseq:NP_009994.2|sgd:S000000664|dip:DIP-5001N|sgd:YCR068W(identity)	refseq:XP_016865274.1|refseq:NP_001139791.1|refseq:NP_001139792.1|refseq:NP_001139793.1|refseq:NP_001139794.1|refseq:NP_076416.2|refseq:XP_005272120.1|ensembl:ENSG00000155324(gene)|ensembl:ENST00000285689(transcript)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0042802"(identical protein binding)|interpro:IPR004182(GRAM)|interpro:IPR011993(Pleckstrin homology-type)|entrezgene/locuslink:65983(identity)	-	crc64:B56ABAB72B999019	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:ttgDIIQIdYUuP+ME547oz2gZuEA559292	rogid:6UkVJddV5/mHpLX/rk00jMwCA+k9606	intact-crc:C93EFB67374EA82D|rigid:O18CJOhduXKvpXhJ8XULUTU5KbU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P25638	uniprotkb:P24278	intact:EBI-21956|uniprotkb:D6VR65|ensemblfungi:YCR060W	intact:EBI-739899|uniprotkb:Q8IYH9|uniprotkb:B3KUX6|ensembl:ENSP00000378204|ensembl:ENSP00000476746	psi-mi:tah1_yeast(display_long)|uniprotkb:YCR60W(orf name)|uniprotkb:YCR060W(locus name)|uniprotkb:TAH1(gene name)|psi-mi:TAH1(display_short)	psi-mi:zbt25_human(display_long)|uniprotkb:ZBTB25(gene name)|psi-mi:ZBTB25(display_short)|uniprotkb:KUP(gene name synonym)|uniprotkb:ZNF46(gene name synonym)|uniprotkb:Zinc finger protein 46(gene name synonym)|uniprotkb:Zinc finger protein KUP(gene name synonym)|uniprotkb:C14orf51(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11524741|imex:IM-24995-254	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009986.1|sgd:S000000656|mint:P25638|dip:DIP-5000N|ensemblfungi:YCR060W(gene)|ensemblfungi:YCR060W_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|go:"GO:0051087"(chaperone binding)|go:"GO:0097255"(R2TP complex)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|rcsb pdb:2L6J|rcsb pdb:2LSU|rcsb pdb:2LSV|rcsb pdb:2MNJ|rcsb pdb:4CGQ|rcsb pdb:4CGU|sgd:YCR060W(identity)	refseq:NP_008908.2|ensembl:ENSG00000089775(gene)|ensembl:ENST00000394715(transcript)|ensembl:ENST00000608382(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:P24278|refseq:NP_001291436.1|refseq:XP_011535445.1|refseq:XP_006720314.1|refseq:XP_006720315.1|refseq:XP_016877121.1|refseq:XP_016877122.1|refseq:XP_016877123.1|refseq:XP_016877124.1|entrezgene/locuslink:7597(identity)	-	crc64:3738DE6F227F803A	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:DXXWcBPtKzTtK2Hp7l4g0ukIZPQ559292	rogid:xi3bM5CoeXvVZNBOzaQlZdWU4ag9606	intact-crc:444FDAAFB51D22A6|rigid:gnRe71VsITlsLNC5wTF4zzIJG8s	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q2NKX8	uniprotkb:P25635	intact:EBI-1042535|uniprotkb:Q8NCI1|uniprotkb:Q96H93|uniprotkb:Q9NXQ8|intact:EBI-2560904|ensembl:ENSP00000334675	intact:EBI-14332|uniprotkb:P25633|uniprotkb:P25636|uniprotkb:D6VR63|ensemblfungi:YCR057C	psi-mi:erc6l_human(display_long)|uniprotkb:ERCC6L(gene name)|psi-mi:ERCC6L(display_short)|uniprotkb:PICH(gene name synonym)|uniprotkb:ATP-dependent helicase ERCC6-like(gene name synonym)|uniprotkb:PLK1-interacting checkpoint helicase(gene name synonym)|uniprotkb:Tumor antigen BJ-HCC-15(gene name synonym)	psi-mi:pwp2_yeast(display_long)|uniprotkb:PWP2(gene name)|psi-mi:PWP2(display_short)|uniprotkb:UTP1(gene name synonym)|uniprotkb:YCR057C(locus name)|uniprotkb:YCR55C/YCR57C/YCR58C(orf name)|uniprotkb:U3 small nucleolar RNA-associated protein 1(gene name synonym)|uniprotkb:U three protein 1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11524712|imex:IM-24995-251	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060139.2|ensembl:ENSG00000186871(gene)|ensembl:ENST00000334463(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0015616"(DNA translocase activity)|go:"GO:0016020"(membrane)|go:"GO:0051301"(cell division)|go:"GO:0070615"|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000330(SNF2-related)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR038718|rcsb pdb:5JNO|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|entrezgene/locuslink:54821(identity)	go:"GO:0000920"(septum digestion after cytokinesis)|go:"GO:0003729"(mRNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030686"(90S preribosome)|go:"GO:0032040"(small-subunit processome)|go:"GO:0034388"(Pwp2p-containing subcomplex of 90S preribosome)|interpro:IPR001680(WD40 repeat)|interpro:IPR007148(Small-subunit processome, Utp12)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR027145|interpro:IPR036322|rcsb pdb:5I2T|rcsb pdb:5WLC|rcsb pdb:5WYJ|ensemblfungi:YCR057C(gene)|ensemblfungi:YCR057C_mRNA(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0000447"("endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|rcsb pdb:5WYK|go:"GO:0000472"("endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000480"("endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|rcsb pdb:6KE6|rcsb pdb:6LQP|rcsb pdb:6LQQ|rcsb pdb:6LQR|rcsb pdb:6LQS|rcsb pdb:6LQT|rcsb pdb:6LQU|rcsb pdb:6LQV|rcsb pdb:6ND4|rcsb pdb:6ZQA|rcsb pdb:6ZQB|rcsb pdb:6ZQC|rcsb pdb:6ZQD|rcsb pdb:6ZQE|rcsb pdb:6ZQF|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-6791226|refseq:NP_009984.1|sgd:S000000653|mint:P25635|dip:DIP-1868N|sgd:YCR057C(identity)	-	-	crc64:CBEE4720F81378B6	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:3HZtZq9pgDyQB+UcxtAQjHv7+7o9606	rogid:3JKhaE50yPlCymnkEC14JB9atNY559292	intact-crc:B1E1CA388BA3FA38|rigid:Lg3oW65HHrRjOLx+yUC5fbxZUKk	false	sufficient binding region:832-1250	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8N4C7	uniprotkb:P25635	intact:EBI-8484990|intact:MINT-6940674|ensembl:ENSP00000320679	intact:EBI-14332|uniprotkb:P25633|uniprotkb:P25636|uniprotkb:D6VR63|ensemblfungi:YCR057C	psi-mi:stx19_human(display_long)|uniprotkb:STX19(gene name)|psi-mi:STX19(display_short)	psi-mi:pwp2_yeast(display_long)|uniprotkb:PWP2(gene name)|psi-mi:PWP2(display_short)|uniprotkb:UTP1(gene name synonym)|uniprotkb:YCR057C(locus name)|uniprotkb:YCR55C/YCR57C/YCR58C(orf name)|uniprotkb:U3 small nucleolar RNA-associated protein 1(gene name synonym)|uniprotkb:U three protein 1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11524723|imex:IM-24995-252	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011511144.1|refseq:NP_001001850.1|ensembl:ENSG00000178750(gene)|ensembl:ENST00000315099(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006887"(exocytosis)|go:"GO:0006906"(vesicle fusion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0048278"(vesicle docking)|go:"GO:0048787"(presynaptic active zone membrane)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006011(Syntaxin, N-terminal)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|interpro:IPR015708(Syntaxin-3)|mint:Q8N4C7|entrezgene/locuslink:415117(identity)	go:"GO:0000920"(septum digestion after cytokinesis)|go:"GO:0003729"(mRNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030686"(90S preribosome)|go:"GO:0032040"(small-subunit processome)|go:"GO:0034388"(Pwp2p-containing subcomplex of 90S preribosome)|interpro:IPR001680(WD40 repeat)|interpro:IPR007148(Small-subunit processome, Utp12)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR027145|interpro:IPR036322|rcsb pdb:5I2T|rcsb pdb:5WLC|rcsb pdb:5WYJ|ensemblfungi:YCR057C(gene)|ensemblfungi:YCR057C_mRNA(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0000447"("endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|rcsb pdb:5WYK|go:"GO:0000472"("endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000480"("endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|rcsb pdb:6KE6|rcsb pdb:6LQP|rcsb pdb:6LQQ|rcsb pdb:6LQR|rcsb pdb:6LQS|rcsb pdb:6LQT|rcsb pdb:6LQU|rcsb pdb:6LQV|rcsb pdb:6ND4|rcsb pdb:6ZQA|rcsb pdb:6ZQB|rcsb pdb:6ZQC|rcsb pdb:6ZQD|rcsb pdb:6ZQE|rcsb pdb:6ZQF|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-6791226|refseq:NP_009984.1|sgd:S000000653|mint:P25635|dip:DIP-1868N|sgd:YCR057C(identity)	-	comment:mint|comment:homomint	crc64:CBEE4720F81378B6	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:FNBoXbeKnFcWR1+dwnaJVvWJ23c9606	rogid:3JKhaE50yPlCymnkEC14JB9atNY559292	intact-crc:9ECB2087DBCA9F1D|rigid:8Xnxl0XOXaN/+rHr2sdkkqDMemY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P25637	uniprotkb:Q96HT8	intact:EBI-21951|uniprotkb:D6VR64|ensemblfungi:YCR059C	intact:EBI-748896|uniprotkb:Q6NXT8|uniprotkb:Q9P0J5|uniprotkb:B2R6R0|ensembl:ENSP00000318154	psi-mi:yih1_yeast(display_long)|uniprotkb:YCR59C(orf name)|uniprotkb:YCR059C(locus name)|uniprotkb:YIH1(gene name)|psi-mi:YIH1(display_short)	psi-mi:mr1l1_human(display_long)|uniprotkb:PP784(orf name)|uniprotkb:MRFAP1L1(gene name)|psi-mi:MRFAP1L1(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11524732|imex:IM-24995-253	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009985.1|sgd:S000000655|mint:P25637|dip:DIP-1846N|ensemblfungi:YCR059C(gene)|ensemblfungi:YCR059C_mRNA(transcript)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0003785"(actin monomer binding)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0033673"(negative regulation of kinase activity)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0043022"(ribosome binding)|go:"GO:0140469"(GCN2-mediated signaling)|go:"GO:1905538"(polysome binding)|interpro:IPR001498(Protein of unknown function UPF0029, N-terminal)|interpro:IPR006575(RWD)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR020568|interpro:IPR020569|interpro:IPR023582|interpro:IPR036956|rcsb pdb:6BQI|rcsb pdb:6U1L|rcsb pdb:6U1O|sgd:YCR059C(identity)	refseq:NP_982287.1|refseq:XP_005247989.1|ensembl:ENSG00000178988(gene)|ensembl:ENST00000320848(transcript)|go:"GO:0042802"(identical protein binding)|interpro:IPR029254|mint:Q96HT8|dip:DIP-29019N|entrezgene/locuslink:114932(identity)	-	-	caution:This sequence has been withdrawn from Uniprot.|crc64:6C914B0B4BEECAE5	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:aAbGir3o4M0LUpwOv6YBC25KpQQ559292	rogid:hb4enqSS7DeieOByDoLDkXkSlIk9606	intact-crc:0DD06695F8FB878A|rigid:DmLeJugk9z8HWbVTC4xBweyUnV0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P26343	uniprotkb:Q8IYF3-3	intact:EBI-5489|uniprotkb:D6VX97|ensemblfungi:YKR034W	intact:EBI-11523345|ensembl:ENSP00000363453	psi-mi:dal80_yeast(display_long)|uniprotkb:YKR034W(locus name)|uniprotkb:DAL80(gene name)|psi-mi:DAL80(display_short)|uniprotkb:UGA43(gene name synonym)|uniprotkb:Regulatory protein UGA43(gene name synonym)	psi-mi:q8iyf3-3(display_long)|uniprotkb:TEX11(gene name)|psi-mi:TEX11(display_short)|uniprotkb:Protein ZIP4 homolog(gene name synonym)|uniprotkb:ZIP4(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11524801|imex:IM-24995-260	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012959.1|sgd:S000001742|dip:DIP-2094N|ensemblfungi:YKR034W(gene)|ensemblfungi:YKR034W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042128"(nitrate assimilation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0090295"(nitrogen catabolite repression of transcription)|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR039355|sgd:YKR034W(identity)	ensembl:ENSG00000120498(gene)|ensembl:ENST00000374333(transcript)|intact:EBI-742397(isoform-parent)|uniprotkb:Q8IYF3-3(isoform-parent)|entrezgene/locuslink:56159(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Qfoc7DZ+/Nwthc4Hf93+iwuYgVg559292	rogid:PUAMFmnm5ZV2rnJ1rhm9ZeRCixg9606	intact-crc:5997240056ABFB35|rigid:1LkqKzGxU6MFIMhwAGfgH8AZjdQ	false	-	sufficient binding region:9-925	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P26343	uniprotkb:Q13643	intact:EBI-5489|uniprotkb:D6VX97|ensemblfungi:YKR034W	intact:EBI-741101|ensembl:ENSP00000362107|uniprotkb:Q6I9T0|uniprotkb:Q9BVA2|uniprotkb:D3DPT6	psi-mi:dal80_yeast(display_long)|uniprotkb:YKR034W(locus name)|uniprotkb:DAL80(gene name)|psi-mi:DAL80(display_short)|uniprotkb:UGA43(gene name synonym)|uniprotkb:Regulatory protein UGA43(gene name synonym)	psi-mi:fhl3_human(display_long)|uniprotkb:FHL3(gene name)|psi-mi:FHL3(display_short)|uniprotkb:SLIM2(gene name synonym)|uniprotkb:Skeletal muscle LIM-protein 2(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11524792|imex:IM-24995-259	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012959.1|sgd:S000001742|dip:DIP-2094N|ensemblfungi:YKR034W(gene)|ensemblfungi:YKR034W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042128"(nitrate assimilation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0090295"(nitrogen catabolite repression of transcription)|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR039355|sgd:YKR034W(identity)	refseq:NP_004459.2|ensembl:ENSG00000183386(gene)|ensembl:ENST00000373016(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005925"(focal adhesion)|go:"GO:0007517"(muscle organ development)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0046872"(metal ion binding)|interpro:IPR001781(Zinc finger, LIM-type)|mint:Q13643|rcsb pdb:1WYH|rcsb pdb:2CUQ|rcsb pdb:2EHE|interpro:IPR037987|refseq:NP_001230807.1|dip:DIP-42030N|entrezgene/locuslink:2275(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Qfoc7DZ+/Nwthc4Hf93+iwuYgVg559292	rogid:RAo+b/VgFSnHSbgR+zXuxJvypxM9606	intact-crc:7590E87A52A4C57F|rigid:OUrGCbGSLz09l+RBSshd6fA3siM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9BQY9-2	uniprotkb:P25651	intact:EBI-11524759|ensembl:ENSP00000349822|ensembl:ENSP00000354250|ensembl:ENSP00000361795|ensembl:ENSP00000361797|ensembl:ENSP00000361808	intact:EBI-22001|uniprotkb:D6VR86|ensemblfungi:YCR086W	psi-mi:q9bqy9-2(display_long)|uniprotkb:DBNDD2(gene name)|psi-mi:DBNDD2(display_short)|uniprotkb:C20orf35(gene name synonym)|uniprotkb:Casein kinase-1 binding protein(gene name synonym)|uniprotkb:HSMNP1(gene name synonym)	psi-mi:csm1_yeast(display_long)|uniprotkb:YCR086W(locus name)|uniprotkb:YCR86W(orf name)|uniprotkb:Chromosome segregation in meiosis protein 1(gene name synonym)|uniprotkb:CSM1(gene name)|psi-mi:CSM1(display_short)|uniprotkb:SPO86(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11524763|imex:IM-24995-256	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-747462(isoform-parent)|ensembl:ENSG00000244274(gene)|ensembl:ENST00000357275(transcript)|ensembl:ENST00000360981(transcript)|ensembl:ENST00000372710(transcript)|ensembl:ENST00000372712(transcript)|ensembl:ENST00000372723(transcript)|entrezgene/locuslink:55861(identity)	refseq:NP_010009.1|sgd:S000000682|dip:DIP-1283N|ensemblfungi:YCR086W(gene)|ensemblfungi:YCR086W_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005730"(nucleolus)|go:"GO:0033551"(monopolin complex)|go:"GO:0034503"(protein localization to nucleolar rDNA repeats)|go:"GO:0034506"(chromosome, centromeric core domain)|go:"GO:0042802"(identical protein binding)|go:"GO:0045132"(meiotic chromosome segregation)|go:"GO:0045143"(homologous chromosome segregation)|go:"GO:0045144"(meiotic sister chromatid segregation)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051455"(monopolar spindle attachment to meiosis I kinetochore)|go:"GO:0070550"(rDNA condensation)|go:"GO:0072686"(mitotic spindle)|go:"GO:1990644"(microtubule site clamp)|interpro:IPR020981|interpro:IPR038608|interpro:IPR040349|interpro:IPR041671|rcsb pdb:3N4R|rcsb pdb:3N4S|rcsb pdb:3N4X|rcsb pdb:3N7N|rcsb pdb:5KTB|rcsb pdb:5V1A|rcsb pdb:5V3N|rcsb pdb:6DEI|mint:P25651|sgd:YCR086W(identity)	-	-	crc64:9650E0DA89B31CC5	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:AfeXaSlYyOOp2QaUjv0FRzdfTNY9606	rogid:rN1hGW+i7AN2+SmrIrwqz4ZSbQk559292	intact-crc:9A437EB6E000E432|rigid:21rU79/LxmF6xVE+3TJFcYKgeYU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P25656	uniprotkb:Q969F0	intact:EBI-22014|uniprotkb:D6VR94|ensemblfungi:YCR094W	intact:EBI-743099|ensembl:ENSP00000359375	psi-mi:cdc50_yeast(display_long)|uniprotkb:YCR94W(orf name)|uniprotkb:YCR094W(locus name)|uniprotkb:CDC50(gene name)|psi-mi:CDC50(display_short)	psi-mi:fate1_human(display_long)|uniprotkb:Tumor antigen BJ-HCC-2(gene name synonym)|uniprotkb:Cancer/testis antigen 43(gene name synonym)|uniprotkb:FATE1(gene name)|psi-mi:FATE1(display_short)|uniprotkb:FATE(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11524772|imex:IM-24995-257	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010018.1|sgd:S000000690|dip:DIP-5138N|ensemblfungi:YCR094W(gene)|ensemblfungi:YCR094W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006897"(endocytosis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0045332"(phospholipid translocation)|go:"GO:0051666"(actin cortical patch localization)|go:"GO:0140331"(aminophospholipid translocation)|go:"GO:1990530"(Cdc50p-Drs2p complex)|interpro:IPR005045(Protein of unknown function DUF284, transmembrane eukaryotic)|rcsb pdb:6PSY|rcsb pdb:6ROH|rcsb pdb:6ROI|rcsb pdb:6ROJ|rcsb pdb:7OH4|rcsb pdb:7OH6|rcsb pdb:7OH7|reactome:R-SCE-6798695|rcsb pdb:6PSX|mint:P25656|sgd:YCR094W(identity)	refseq:NP_149076.1|ensembl:ENSG00000147378(gene)|ensembl:ENST00000370350(transcript)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|go:"GO:0051562"(negative regulation of mitochondrial calcium ion concentration)|interpro:IPR039153|interpro:IPR039433|mint:Q969F0|entrezgene/locuslink:89885(identity)	-	crc64:565575CA402C0C91	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:zVi09MNh1hpBUuc5AzasxmCrnKY559292	rogid:Nm1N6lO92MHr5rIKC007oouF5RE9606	intact-crc:3C8BF18ACE0DA0A5|rigid:Wvf8VIUEVahkuI+cHqFOqMHyVSU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q08379	uniprotkb:P26343	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	intact:EBI-5489|uniprotkb:D6VX97|ensemblfungi:YKR034W	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:dal80_yeast(display_long)|uniprotkb:YKR034W(locus name)|uniprotkb:DAL80(gene name)|psi-mi:DAL80(display_short)|uniprotkb:UGA43(gene name synonym)|uniprotkb:Regulatory protein UGA43(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11524781|imex:IM-24995-258	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N|entrezgene/locuslink:2801(identity)	refseq:NP_012959.1|sgd:S000001742|dip:DIP-2094N|ensemblfungi:YKR034W(gene)|ensemblfungi:YKR034W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042128"(nitrate assimilation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0090295"(nitrogen catabolite repression of transcription)|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR039355|sgd:YKR034W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2017/05/26	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	rogid:Qfoc7DZ+/Nwthc4Hf93+iwuYgVg559292	intact-crc:A30E1079B1D9F092|rigid:/MJXVD3xlFybQYVPoql6KjIiCSY	false	sufficient binding region:383-1002	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P26448	uniprotkb:Q8NA61-2	intact:EBI-3824|uniprotkb:D6VZN0|ensemblfungi:YMR055C	intact:EBI-11524851|ensembl:ENSP00000368249|ensembl:ENSP00000480148	psi-mi:bub2_yeast(display_long)|uniprotkb:BUB2(gene name)|psi-mi:BUB2(display_short)|uniprotkb:YMR055C(locus name)|uniprotkb:YM9796.08C(orf name)|uniprotkb:Cell cycle arrest protein BUB2(gene name synonym)	psi-mi:q8na61-2(display_long)|uniprotkb:CBY2(gene name)|psi-mi:CBY2(display_short)|uniprotkb:SPERT(gene name synonym)|uniprotkb:Spermatid-associated protein(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11524855|imex:IM-24995-265	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013771.1|sgd:S000004659|dip:DIP-1215N|mint:P26448|ensemblfungi:YMR055C(gene)|ensemblfungi:YMR055C_mRNA(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0031030"(negative regulation of septation initiation signaling)|go:"GO:0031578"(mitotic spindle orientation checkpoint signaling)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0051301"(cell division)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:1902543"(negative regulation of protein localization to mitotic spindle pole body)|go:"GO:1990334"(Bfa1-Bub2 complex)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR035969|sgd:YMR055C(identity)	intact:EBI-741724(isoform-parent)|ensembl:ENSG00000174015(gene)|ensembl:ENST00000378966(transcript)|ensembl:ENST00000610924(transcript)|uniprotkb:Q8NA61-2(isoform-parent)|entrezgene/locuslink:220082(identity)	-	crc64:A1DDBFB548E81EA3	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:+03m4HOOcKjpSjqpEZ8wCgD2Egc559292	rogid:SogYcXGGMYRYzB9xKC5o0pEtsDs9606	intact-crc:36384964CBE1C579|rigid:aQWoQmRaxtbCXfezUSu0zlJ/56g	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P26448	uniprotkb:Q8N6Y0	intact:EBI-3824|uniprotkb:D6VZN0|ensemblfungi:YMR055C	intact:EBI-739895|uniprotkb:Q8NBX7|uniprotkb:Q96KH3|uniprotkb:Q9BYI8|uniprotkb:A8K7L6|uniprotkb:B2RCR9|ensembl:ENSP00000252597	psi-mi:bub2_yeast(display_long)|uniprotkb:BUB2(gene name)|psi-mi:BUB2(display_short)|uniprotkb:YMR055C(locus name)|uniprotkb:YM9796.08C(orf name)|uniprotkb:Cell cycle arrest protein BUB2(gene name synonym)	psi-mi:usbp1_human(display_long)|uniprotkb:USHBP1(gene name)|psi-mi:USHBP1(display_short)|uniprotkb:MCC-2(gene name synonym)|uniprotkb:AIE-75-binding protein(gene name synonym)|uniprotkb:AIEBP(gene name synonym)|uniprotkb:MCC2(gene name synonym)|uniprotkb:Mutated in colon cancer protein 2(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11524842|imex:IM-24995-264	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013771.1|sgd:S000004659|dip:DIP-1215N|mint:P26448|ensemblfungi:YMR055C(gene)|ensemblfungi:YMR055C_mRNA(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0031030"(negative regulation of septation initiation signaling)|go:"GO:0031578"(mitotic spindle orientation checkpoint signaling)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0051301"(cell division)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:1902543"(negative regulation of protein localization to mitotic spindle pole body)|go:"GO:1990334"(Bfa1-Bub2 complex)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR035969|sgd:YMR055C(identity)	refseq:NP_001284632.1|refseq:NP_114147.2|refseq:NP_001308346.1|ensembl:ENSG00000130307(gene)|ensembl:ENST00000252597(transcript)|go:"GO:0030165"(PDZ domain binding)|interpro:IPR019536|interpro:IPR040171|entrezgene/locuslink:83878(identity)	-	crc64:A1DDBFB548E81EA3	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:+03m4HOOcKjpSjqpEZ8wCgD2Egc559292	rogid:vY1qx73Ju/z7WDu6k1kd10ZDVRo9606	intact-crc:E73E6A8731526A64|rigid:OJuPXnRBhcxEYj7Fg2EWN3c+DGI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P26343	uniprotkb:Q9HCM9-2	intact:EBI-5489|uniprotkb:D6VX97|ensemblfungi:YKR034W	intact:EBI-11523450|ensembl:ENSP00000365847|ensembl:ENSP00000373095|ensembl:ENSP00000373097|ensembl:ENSP00000379797|ensembl:ENSP00000379800|ensembl:ENSP00000383486|ensembl:ENSP00000387445|ensembl:ENSP00000389198|ensembl:ENSP00000389852|ensembl:ENSP00000392130|ensembl:ENSP00000394353|ensembl:ENSP00000396986|ensembl:ENSP00000398956|ensembl:ENSP00000401071|ensembl:ENSP00000401184|ensembl:ENSP00000404340|ensembl:ENSP00000404904|ensembl:ENSP00000411582|ensembl:ENSP00000412743|ensembl:ENSP00000414525|ensembl:ENSP00000415259	psi-mi:dal80_yeast(display_long)|uniprotkb:YKR034W(locus name)|uniprotkb:DAL80(gene name)|psi-mi:DAL80(display_short)|uniprotkb:UGA43(gene name synonym)|uniprotkb:Regulatory protein UGA43(gene name synonym)	psi-mi:q9hcm9-2(display_long)|uniprotkb:TRIM39(gene name)|psi-mi:TRIM39(display_short)|uniprotkb:RING finger protein 23(gene name synonym)|uniprotkb:RNF23(gene name synonym)|uniprotkb:TFP(gene name synonym)|uniprotkb:Testis-abundant finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 39(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM39(gene name synonym)|uniprotkb:TIM39beta(isoform synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11524812|imex:IM-24995-261	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012959.1|sgd:S000001742|dip:DIP-2094N|ensemblfungi:YKR034W(gene)|ensemblfungi:YKR034W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042128"(nitrate assimilation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0090295"(nitrogen catabolite repression of transcription)|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR039355|sgd:YKR034W(identity)	intact:EBI-739510(isoform-parent)|ensembl:ENSG00000204599(gene)|ensembl:ENSG00000206495(gene)|ensembl:ENSG00000224994(gene)|ensembl:ENSG00000226437(gene)|ensembl:ENSG00000229929(gene)|ensembl:ENSG00000230308(gene)|ensembl:ENSG00000232839(gene)|ensembl:ENST00000376659(transcript)|ensembl:ENST00000383601(transcript)|ensembl:ENST00000383603(transcript)|ensembl:ENST00000396548(transcript)|ensembl:ENST00000396551(transcript)|ensembl:ENST00000400644(transcript)|ensembl:ENST00000414015(transcript)|ensembl:ENST00000419790(transcript)|ensembl:ENST00000430502(transcript)|ensembl:ENST00000431272(transcript)|ensembl:ENST00000433900(transcript)|ensembl:ENST00000438076(transcript)|ensembl:ENST00000438859(transcript)|ensembl:ENST00000440117(transcript)|ensembl:ENST00000443109(transcript)|ensembl:ENST00000446397(transcript)|ensembl:ENST00000449318(transcript)|ensembl:ENST00000450778(transcript)|ensembl:ENST00000451132(transcript)|ensembl:ENST00000452705(transcript)|ensembl:ENST00000458607(transcript)|uniprotkb:Q9HCM9-2(isoform-parent)|entrezgene/locuslink:56658(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Qfoc7DZ+/Nwthc4Hf93+iwuYgVg559292	rogid:UfSn2+IVRxtGomVeDGdZpL7mz5I9606	intact-crc:75F9B92C956B6E9A|rigid:yi5zVgyt3q9xUyRgtYtQ4W4qgXI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O15156-2	uniprotkb:P26448	intact:EBI-11522250|ensembl:ENSP00000406286	intact:EBI-3824|uniprotkb:D6VZN0|ensemblfungi:YMR055C	psi-mi:o15156-2(display_long)|uniprotkb:ZBTB7B(gene name)|psi-mi:ZBTB7B(display_short)|uniprotkb:Krueppel-related zinc finger protein cKrox(gene name synonym)|uniprotkb:T-helper-inducing POZ/Krueppel-like factor(gene name synonym)|uniprotkb:ZBTB15(gene name synonym)|uniprotkb:ZFP67(gene name synonym)|uniprotkb:ZNF857B(gene name synonym)|uniprotkb:Zinc finger and BTB domain-containing protein 15(gene name synonym)|uniprotkb:Zinc finger protein 67 homolog(gene name synonym)|uniprotkb:Zinc finger protein 857B(gene name synonym)|uniprotkb:Zinc finger protein Th-POK(gene name synonym)	psi-mi:bub2_yeast(display_long)|uniprotkb:BUB2(gene name)|psi-mi:BUB2(display_short)|uniprotkb:YMR055C(locus name)|uniprotkb:YM9796.08C(orf name)|uniprotkb:Cell cycle arrest protein BUB2(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11524822|imex:IM-24995-262	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-740434(isoform-parent)|ensembl:ENSG00000160685(gene)|ensembl:ENST00000417934(transcript)|uniprotkb:O15156-2(isoform-parent)|entrezgene/locuslink:51043(identity)	refseq:NP_013771.1|sgd:S000004659|dip:DIP-1215N|mint:P26448|ensemblfungi:YMR055C(gene)|ensemblfungi:YMR055C_mRNA(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0031030"(negative regulation of septation initiation signaling)|go:"GO:0031578"(mitotic spindle orientation checkpoint signaling)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0051301"(cell division)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:1902543"(negative regulation of protein localization to mitotic spindle pole body)|go:"GO:1990334"(Bfa1-Bub2 complex)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR035969|sgd:YMR055C(identity)	-	isoform-comment:No experimental confirmation available.	crc64:A1DDBFB548E81EA3	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:41NEFYyprTXI+fOHVFh78TPKF289606	rogid:+03m4HOOcKjpSjqpEZ8wCgD2Egc559292	intact-crc:033540B81795EE85|rigid:ahVGA7Cxy0MID1b7oFyljnjiRUM	false	sufficient binding region:35-573	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q5JST6	uniprotkb:P26448	intact:EBI-2349927|uniprotkb:Q9H653|uniprotkb:Q5JST8|uniprotkb:Q68DK4|uniprotkb:Q8NEI0|intact:EBI-28971886|ensembl:ENSP00000404232	intact:EBI-3824|uniprotkb:D6VZN0|ensemblfungi:YMR055C	psi-mi:efhc2_human(display_long)|uniprotkb:EFHC2(gene name)|psi-mi:EFHC2(display_short)	psi-mi:bub2_yeast(display_long)|uniprotkb:BUB2(gene name)|psi-mi:BUB2(display_short)|uniprotkb:YMR055C(locus name)|uniprotkb:YM9796.08C(orf name)|uniprotkb:Cell cycle arrest protein BUB2(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11524833|imex:IM-24995-263	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000404232|refseq:NP_079460.2|ensembl:ENSG00000183690(gene)|ensembl:ENST00000420999(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005930"(axoneme)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0060285"(cilium-dependent cell motility)|go:"GO:0072686"(mitotic spindle)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR006602(Region of unknown function DM10)|interpro:IPR011992(EF-Hand type)|interpro:IPR040193|rcsb pdb:2Z13|rcsb pdb:2Z14|entrezgene/locuslink:80258(identity)	refseq:NP_013771.1|sgd:S000004659|dip:DIP-1215N|mint:P26448|ensemblfungi:YMR055C(gene)|ensemblfungi:YMR055C_mRNA(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0031030"(negative regulation of septation initiation signaling)|go:"GO:0031578"(mitotic spindle orientation checkpoint signaling)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0051301"(cell division)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:1902543"(negative regulation of protein localization to mitotic spindle pole body)|go:"GO:1990334"(Bfa1-Bub2 complex)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR035969|sgd:YMR055C(identity)	-	-	crc64:A1DDBFB548E81EA3	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:O1XriQSkLcYkk7H7AlanQ1FKIBY9606	rogid:+03m4HOOcKjpSjqpEZ8wCgD2Egc559292	intact-crc:6BBC7E48C4DEA158|rigid:zdhzFGfHhDSLfJrIv4Q+DERAIGw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9HD26-2	uniprotkb:P27882	intact:EBI-11102276|ensembl:ENSP00000052569	intact:EBI-6621|uniprotkb:D6VUG4|ensemblfungi:YGR029W	psi-mi:q9hd26-2(display_long)|uniprotkb:GOPC(gene name)|psi-mi:GOPC(display_short)|uniprotkb:CAL(gene name synonym)|uniprotkb:CFTR-associated ligand(gene name synonym)|uniprotkb:FIG(gene name synonym)|uniprotkb:Fused in glioblastoma(gene name synonym)|uniprotkb:PDZ protein interacting specifically with TC10(gene name synonym)	psi-mi:erv1_yeast(display_long)|uniprotkb:Essential for respiration and vegetative growth protein 1(gene name synonym)|uniprotkb:14 kDa regulatory protein(gene name synonym)|uniprotkb:ERV1(gene name)|psi-mi:ERV1(display_short)|uniprotkb:YGR029W(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11524904|imex:IM-24995-270	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000047932(gene)|ensembl:ENST00000052569(transcript)|intact:EBI-349832(isoform-parent)|uniprotkb:Q9HD26-2(isoform-parent)|entrezgene/locuslink:57120(identity)	refseq:NP_011543.4|sgd:S000003261|interpro:IPR017905|interpro:IPR036774|mint:P27882|interpro:IPR039799|ensemblfungi:YGR029W(gene)|ensemblfungi:YGR029W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0016971"(flavin-linked sulfhydryl oxidase activity)|go:"GO:0016972"(thiol oxidase activity)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0045041"(protein import into mitochondrial intermembrane space)|go:"GO:0050660"(flavin adenine dinucleotide binding)|rcsb pdb:3W4Y|rcsb pdb:4E0H|rcsb pdb:4E0I|sgd:YGR029W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:QoEGY54FfmwTrpGVMQN9ASGPgVI9606	rogid:nYYS2xiutIkSeWN8DabWui0hzr4559292	intact-crc:8383AA6CEB1AE4FA|rigid:xOqd6gwSBIX/gIXoj2DzzoCzauI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P27515	uniprotkb:P63279	intact:EBI-20151|uniprotkb:D6W1I7|ensemblfungi:YNR012W	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	psi-mi:urk1_yeast(display_long)|uniprotkb:URK1(gene name)|psi-mi:URK1(display_short)|uniprotkb:YNR012W(locus name)|uniprotkb:N2050(orf name)|uniprotkb:Uridine monophosphokinase(gene name synonym)	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11524895|imex:IM-24995-269	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014409.1|sgd:S000005295|ensemblfungi:YNR012W(gene)|ensemblfungi:YNR012W_mRNA(transcript)|go:"GO:0004849"(uridine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008655"(pyrimidine-containing compound salvage)|go:"GO:0009116"(nucleoside metabolic process)|go:"GO:0044206"(UMP salvage)|go:"GO:0044211"(CTP salvage)|interpro:IPR000764(Uridine kinase)|interpro:IPR000836(Phosphoribosyltransferase)|interpro:IPR006083(Phosphoribulokinase/uridine kinase)|interpro:IPR027417|interpro:IPR029057|dip:DIP-1720N|reactome:R-SCE-196807|reactome:R-SCE-73614|sgd:YNR012W(identity)	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N|entrezgene/locuslink:7329(identity)	-	crc64:30A0592899BCD040	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:0b4r1zm128hRdLTzXIPi6wctZZE559292	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	intact-crc:0C4715C9D81111C8|rigid:yK2Y7p5AY+W2Gkq+u9zS/BqQUX4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P26448	uniprotkb:Q96AA8	intact:EBI-3824|uniprotkb:D6VZN0|ensemblfungi:YMR055C	intact:EBI-752007|uniprotkb:O60302|uniprotkb:B4DSG0|uniprotkb:A4ZZA7|uniprotkb:Q548S1|uniprotkb:A8K5G5|uniprotkb:G5E9Y0|ensembl:ENSP00000265272	psi-mi:bub2_yeast(display_long)|uniprotkb:BUB2(gene name)|psi-mi:BUB2(display_short)|uniprotkb:YMR055C(locus name)|uniprotkb:YM9796.08C(orf name)|uniprotkb:Cell cycle arrest protein BUB2(gene name synonym)	psi-mi:jkip2_human(display_long)|uniprotkb:JAMIP2(gene name synonym)|uniprotkb:NECC1(gene name synonym)|uniprotkb:Neuroendocrine long coiled-coil protein 1(gene name synonym)|uniprotkb:CTCL tumor antigen HD-CL-04(gene name synonym)|uniprotkb:JAKMIP2(gene name)|psi-mi:JAKMIP2(display_short)|uniprotkb:KIAA0555(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11524864|imex:IM-24995-266	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013771.1|sgd:S000004659|dip:DIP-1215N|mint:P26448|ensemblfungi:YMR055C(gene)|ensemblfungi:YMR055C_mRNA(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0031030"(negative regulation of septation initiation signaling)|go:"GO:0031578"(mitotic spindle orientation checkpoint signaling)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0051301"(cell division)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:1902543"(negative regulation of protein localization to mitotic spindle pole body)|go:"GO:1990334"(Bfa1-Bub2 complex)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR035969|sgd:YMR055C(identity)	refseq:NP_055605.2|refseq:NP_001257870.1|refseq:NP_001257863.1|refseq:NP_001269211.1|refseq:XP_016865586.1|ensembl:ENSG00000176049(gene)|ensembl:ENST00000265272(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0008017"(microtubule binding)|go:"GO:0019900"(kinase binding)|interpro:IPR024836|interpro:IPR031994|entrezgene/locuslink:9832(identity)	-	crc64:A1DDBFB548E81EA3	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:+03m4HOOcKjpSjqpEZ8wCgD2Egc559292	rogid:WnaHkeDBQXut9F9AzzaCrDYpmAE9606	intact-crc:8844F43AD61CFA96|rigid:QAgHLUiC270GVGiAuKnK088snIY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P10644	uniprotkb:P27344	intact:EBI-476431|uniprotkb:Q567S7|uniprotkb:K7ER48|ensembl:ENSP00000351410|ensembl:ENSP00000376475|ensembl:ENSP00000445625|ensembl:ENSP00000464977|ensembl:ENSP00000466459	intact:EBI-6076|uniprotkb:D6VQS3|ensemblfungi:YBR278W	psi-mi:kap0_human(display_long)|uniprotkb:Tissue-specific extinguisher 1(gene name synonym)|uniprotkb:PRKAR1A(gene name)|psi-mi:PRKAR1A(display_short)|uniprotkb:PKR1(gene name synonym)|uniprotkb:PRKAR1(gene name synonym)|uniprotkb:TSE1(gene name synonym)	psi-mi:dpb3_yeast(display_long)|uniprotkb:DPB3(gene name)|psi-mi:DPB3(display_short)|uniprotkb:YBR278W(locus name)|uniprotkb:YBR2015(orf name)|uniprotkb:DNA polymerase II subunit C(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11524873|imex:IM-24995-267	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002725.1|refseq:NP_997636.1|refseq:NP_997637.1|refseq:XP_011523285.1|refseq:XP_011523286.1|refseq:XP_011523287.1|refseq:NP_001263218.1|refseq:NP_001263219.1|refseq:NP_001265362.1|dip:DIP-34368N|ensembl:ENSG00000108946(gene)|ensembl:ENST00000358598(transcript)|ensembl:ENST00000392711(transcript)|ensembl:ENST00000536854(transcript)|ensembl:ENST00000586397(transcript)|ensembl:ENST00000589228(transcript)|go:"GO:0001707"(mesoderm formation)|go:"GO:0004862"(cAMP-dependent protein kinase inhibitor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005771"(multivesicular body)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005952"(cAMP-dependent protein kinase complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007143"(female meiotic nuclear division)|go:"GO:0008603"(cAMP-dependent protein kinase regulator activity)|go:"GO:0010738"(regulation of protein kinase A signaling)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030552"(cAMP binding)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043949"(regulation of cAMP-mediated signaling)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045835"(negative regulation of meiotic nuclear division)|go:"GO:0046007"(negative regulation of activated T cell proliferation)|go:"GO:0060038"(cardiac muscle cell proliferation)|go:"GO:0097224"(sperm connecting piece)|go:"GO:0097546"(ciliary base)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:2000480"(negative regulation of cAMP-dependent protein kinase activity)|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR003117(cAMP-dependent protein kinase, regulatory subunit, type I/II alpha/beta)|interpro:IPR012198(cAMP-dependent protein kinase regulatory subunit)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR018488|rcsb pdb:5KJZ|reactome:R-HSA-163615|reactome:R-HSA-164378|reactome:R-HSA-180024|reactome:R-HSA-381676|reactome:R-HSA-432040|reactome:R-HSA-442720|reactome:R-HSA-5610787|reactome:R-HSA-9660821|reactome:R-HSA-9664323|reactome:R-HSA-983231|interpro:IPR018490|mint:P10644|rcsb pdb:5KJX|rcsb pdb:5KJY|entrezgene/locuslink:5573(identity)	refseq:NP_009837.1|sgd:S000000482|dip:DIP-4803N|mint:P27344|ensemblfungi:YBR278W(gene)|ensemblfungi:YBR278W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006272"(leading strand elongation)|go:"GO:0008622"(epsilon DNA polymerase complex)|go:"GO:0008623"(CHRAC)|go:"GO:0042276"(error-prone translesion synthesis)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0070868"(obsolete heterochromatin organization involved in chromatin silencing)|go:"GO:0090305"(nucleic acid phosphodiester bond hydrolysis)|interpro:IPR009072(Histone-fold)|rcsb pdb:6WJV|reactome:R-SCE-5656169|reactome:R-SCE-6782135|reactome:R-SCE-68952|reactome:R-SCE-68962|sgd:YBR278W(identity)	-	-	crc64:288913917D49C7F9	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:dUZaCJQnC0KZEG4pccIqoT066VY9606	rogid:vWWMmgZ4w7G1VF2V2TDY8cZpKas559292	intact-crc:FE10A5A5D8B016F5|rigid:DsFGaxwbG19Q0h9U1iDVuL5sUZw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q14141-4	uniprotkb:P27476	intact:EBI-11524882|ensembl:ENSP00000346169	intact:EBI-12274|ensemblfungi:YGR159C|uniprotkb:D6VUT9	psi-mi:q14141-4(display_long)|uniprotkb:SEPTIN6(gene name)|psi-mi:SEPTIN6(display_short)|uniprotkb:KIAA0128(gene name synonym)|uniprotkb:SEP2(gene name synonym)|uniprotkb:SEPT6(gene name synonym)	psi-mi:nsr1_yeast(display_long)|uniprotkb:NSR1(gene name)|psi-mi:NSR1(display_short)|uniprotkb:YGR159C(locus name)|uniprotkb:G7001(orf name)|uniprotkb:p67(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11524886|imex:IM-24995-268	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000125354(gene)|ensembl:ENST00000354228(transcript)|intact:EBI-745901(isoform-parent)|entrezgene/locuslink:23157(identity)	ensemblfungi:YGR159C(gene)|ensemblfungi:YGR159C_mRNA(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006364"(rRNA processing)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0043047"(single-stranded telomeric DNA binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034276|interpro:IPR035979|interpro:IPR034272|refseq:NP_011675.1|sgd:S000003391|mint:P27476|dip:DIP-5537N|sgd:YGR159C(identity)	-	-	crc64:90DEEE7BBC20BC0C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:QfLbdoBUG/Q5IYeoadJOtAK+kj49606	rogid:q0/AgJC55iTpn/5kCsxal2kQ7Ls559292	intact-crc:1EB9F5B626CFC56A|rigid:XNO6KTqFQk4W9Ap+A+2Gcj+WX/A	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P14373	uniprotkb:P28004	intact:EBI-719493|uniprotkb:A2BE15|uniprotkb:Q5RJA8|uniprotkb:Q5ST26|uniprotkb:Q6LA73|uniprotkb:Q6NXR9|uniprotkb:Q9BZY6|uniprotkb:Q9UJL3|ensembl:ENSP00000383555|ensembl:ENSP00000392787|ensembl:ENSP00000405229|ensembl:ENSP00000414793|ensembl:ENSP00000366404	intact:EBI-20640|uniprotkb:D6VPI6|ensemblfungi:YAL032C	psi-mi:tri27_human(display_long)|uniprotkb:TRIM27(gene name)|psi-mi:TRIM27(display_short)|uniprotkb:RNF76(gene name synonym)|uniprotkb:RFP(gene name synonym)|uniprotkb:Ret finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 27(gene name synonym)|uniprotkb:RING finger protein 76(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM27(gene name synonym)	psi-mi:prp45_yeast(display_long)|uniprotkb:YAL032C(locus name)|uniprotkb:PRP45(gene name)|psi-mi:PRP45(display_short)|uniprotkb:FUN20(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11524944|imex:IM-24995-274	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006501.1|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0090281"(negative regulation of calcium ion import)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR020457|interpro:IPR035791|interpro:IPR043136|mint:P14373|reactome:R-HSA-3232142|reactome:R-HSA-9635465|reactome:R-HSA-8948751|ensembl:ENSG00000204713(gene)|ensembl:ENSG00000215641(gene)|ensembl:ENSG00000229006(gene)|ensembl:ENSG00000234495(gene)|ensembl:ENSG00000237071(gene)|ensembl:ENST00000377199(transcript)|ensembl:ENST00000400720(transcript)|ensembl:ENST00000431123(transcript)|ensembl:ENST00000435528(transcript)|ensembl:ENST00000437160(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001650"(fibrillar center)|go:"GO:0002820"(negative regulation of adaptive immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|entrezgene/locuslink:5987(identity)	refseq:NP_009370.1|sgd:S000000030|ensemblfungi:YAL032C(gene)|ensemblfungi:YAL032C_mRNA(transcript)|go:"GO:0000350"(generation of catalytic spliceosome for second transesterification step)|go:"GO:0005634"(nucleus)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|interpro:IPR004015(SKIP/SNW)|interpro:IPR017862|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|dip:DIP-2774N|mint:P28004|sgd:YAL032C(identity)	-	-	crc64:FE5A724186D7FE84	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:dsfH5OUghD8KSaTz1SFw9OYVTK49606	rogid:qoHF1UsO3k+JOTOfigSuy2P84/k559292	intact-crc:D0105227A430D196|rigid:l1EOZvLuHrmcXFflP1U/fSP6oOQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q08379	uniprotkb:P28004	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	intact:EBI-20640|uniprotkb:D6VPI6|ensemblfungi:YAL032C	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:prp45_yeast(display_long)|uniprotkb:YAL032C(locus name)|uniprotkb:PRP45(gene name)|psi-mi:PRP45(display_short)|uniprotkb:FUN20(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11524913|imex:IM-24995-271	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N|entrezgene/locuslink:2801(identity)	refseq:NP_009370.1|sgd:S000000030|ensemblfungi:YAL032C(gene)|ensemblfungi:YAL032C_mRNA(transcript)|go:"GO:0000350"(generation of catalytic spliceosome for second transesterification step)|go:"GO:0005634"(nucleus)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|interpro:IPR004015(SKIP/SNW)|interpro:IPR017862|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|dip:DIP-2774N|mint:P28004|sgd:YAL032C(identity)	-	-	crc64:FE5A724186D7FE84	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2017/05/26	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	rogid:qoHF1UsO3k+JOTOfigSuy2P84/k559292	intact-crc:80E4E6AB92FCA85D|rigid:X6brJ2YxTeJSL1sKbSylOWcmUo0	false	sufficient binding region:383-1002	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P28004	uniprotkb:O15156-2	intact:EBI-20640|uniprotkb:D6VPI6|ensemblfungi:YAL032C	intact:EBI-11522250|ensembl:ENSP00000406286	psi-mi:prp45_yeast(display_long)|uniprotkb:YAL032C(locus name)|uniprotkb:PRP45(gene name)|psi-mi:PRP45(display_short)|uniprotkb:FUN20(gene name synonym)	psi-mi:o15156-2(display_long)|uniprotkb:ZBTB7B(gene name)|psi-mi:ZBTB7B(display_short)|uniprotkb:Krueppel-related zinc finger protein cKrox(gene name synonym)|uniprotkb:T-helper-inducing POZ/Krueppel-like factor(gene name synonym)|uniprotkb:ZBTB15(gene name synonym)|uniprotkb:ZFP67(gene name synonym)|uniprotkb:ZNF857B(gene name synonym)|uniprotkb:Zinc finger and BTB domain-containing protein 15(gene name synonym)|uniprotkb:Zinc finger protein 67 homolog(gene name synonym)|uniprotkb:Zinc finger protein 857B(gene name synonym)|uniprotkb:Zinc finger protein Th-POK(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11524924|imex:IM-24995-272	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009370.1|sgd:S000000030|ensemblfungi:YAL032C(gene)|ensemblfungi:YAL032C_mRNA(transcript)|go:"GO:0000350"(generation of catalytic spliceosome for second transesterification step)|go:"GO:0005634"(nucleus)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|interpro:IPR004015(SKIP/SNW)|interpro:IPR017862|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|dip:DIP-2774N|mint:P28004|sgd:YAL032C(identity)	intact:EBI-740434(isoform-parent)|ensembl:ENSG00000160685(gene)|ensembl:ENST00000417934(transcript)|uniprotkb:O15156-2(isoform-parent)|entrezgene/locuslink:51043(identity)	-	crc64:FE5A724186D7FE84	isoform-comment:No experimental confirmation available.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:qoHF1UsO3k+JOTOfigSuy2P84/k559292	rogid:41NEFYyprTXI+fOHVFh78TPKF289606	intact-crc:0424B92483FB90C4|rigid:8oaC+Ggh9JirICSVORCrzjxdpwY	false	-	sufficient binding region:35-573	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O95751	uniprotkb:P28004	intact:EBI-740738|ensembl:ENSP00000359557|uniprotkb:Q6IAR6	intact:EBI-20640|uniprotkb:D6VPI6|ensemblfungi:YAL032C	psi-mi:ldoc1_human(display_long)|uniprotkb:Leucine zipper protein down-regulated in cancer cells(gene name synonym)|uniprotkb:LDOC1(gene name)|psi-mi:LDOC1(display_short)|uniprotkb:BCUR1(gene name synonym)	psi-mi:prp45_yeast(display_long)|uniprotkb:YAL032C(locus name)|uniprotkb:PRP45(gene name)|psi-mi:PRP45(display_short)|uniprotkb:FUN20(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11524935|imex:IM-24995-273	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_036449.1|ensembl:ENSG00000182195(gene)|ensembl:ENST00000370526(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071225"(cellular response to muramyl dipeptide)|interpro:IPR032549|interpro:IPR032567|entrezgene/locuslink:23641(identity)	refseq:NP_009370.1|sgd:S000000030|ensemblfungi:YAL032C(gene)|ensemblfungi:YAL032C_mRNA(transcript)|go:"GO:0000350"(generation of catalytic spliceosome for second transesterification step)|go:"GO:0005634"(nucleus)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|interpro:IPR004015(SKIP/SNW)|interpro:IPR017862|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|dip:DIP-2774N|mint:P28004|sgd:YAL032C(identity)	-	-	crc64:FE5A724186D7FE84	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Ediu0oNiZ/+YVY8l3fNdgP5A+v09606	rogid:qoHF1UsO3k+JOTOfigSuy2P84/k559292	intact-crc:7D194D57EAD10DA3|rigid:5eAIzeJUFQEBthjaT++xS7X6z0Y	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P43365	uniprotkb:P28004	intact:EBI-749530|uniprotkb:Q9NSD3|intact:EBI-10178394|uniprotkb:Q6FHH8|ensembl:ENSP00000350592|ensembl:ENSP00000377447|ensembl:ENSP00000377478	intact:EBI-20640|uniprotkb:D6VPI6|ensemblfungi:YAL032C	psi-mi:magac_human(display_long)|uniprotkb:MAGE-12 antigen(gene name synonym)|uniprotkb:MAGE12F antigen(gene name synonym)|uniprotkb:Cancer/testis antigen 1.12(gene name synonym)|uniprotkb:MAGEA12(gene name)|psi-mi:MAGEA12(display_short)|uniprotkb:MAGE12(gene name synonym)	psi-mi:prp45_yeast(display_long)|uniprotkb:YAL032C(locus name)|uniprotkb:PRP45(gene name)|psi-mi:PRP45(display_short)|uniprotkb:FUN20(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11524971|imex:IM-24995-277	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001159858.1|refseq:NP_001159859.1|refseq:NP_005358.2|ensembl:ENSG00000213401(gene)|ensembl:ENST00000357916(transcript)|ensembl:ENST00000393869(transcript)|ensembl:ENST00000393900(transcript)|interpro:IPR002190(MAGE protein)|interpro:IPR021072|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|entrezgene/locuslink:4111(identity)	refseq:NP_009370.1|sgd:S000000030|ensemblfungi:YAL032C(gene)|ensemblfungi:YAL032C_mRNA(transcript)|go:"GO:0000350"(generation of catalytic spliceosome for second transesterification step)|go:"GO:0005634"(nucleus)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|interpro:IPR004015(SKIP/SNW)|interpro:IPR017862|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|dip:DIP-2774N|mint:P28004|sgd:YAL032C(identity)	-	-	crc64:FE5A724186D7FE84	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:3/Jxz2VsFOb67RWqWj3xbTrw3s49606	rogid:qoHF1UsO3k+JOTOfigSuy2P84/k559292	intact-crc:55A408FA55CBFC89|rigid:G+FbStO3V9B8noWIKuGba0HFTkE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P19012	uniprotkb:P28004	intact:EBI-739566|uniprotkb:Q53XV8|uniprotkb:Q9BUG4|uniprotkb:B3KQY1|uniprotkb:B3KRA2|uniprotkb:E0CX14|ensembl:ENSP00000254043|ensembl:ENSP00000377546	intact:EBI-20640|uniprotkb:D6VPI6|ensemblfungi:YAL032C	psi-mi:k1c15_human(display_long)|uniprotkb:KRT15(gene name)|psi-mi:KRT15(display_short)|uniprotkb:KRTB(gene name synonym)|uniprotkb:Cytokeratin-15(gene name synonym)|uniprotkb:Keratin-15(gene name synonym)	psi-mi:prp45_yeast(display_long)|uniprotkb:YAL032C(locus name)|uniprotkb:PRP45(gene name)|psi-mi:PRP45(display_short)|uniprotkb:FUN20(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11524953|imex:IM-24995-275	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002266.2|ensembl:ENSG00000171346(gene)|ensembl:ENST00000254043(transcript)|ensembl:ENST00000393976(transcript)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0008544"(epidermis development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097110"(scaffold protein binding)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR039008|mint:P19012|reactome:R-HSA-6805567|reactome:R-HSA-6809371|entrezgene/locuslink:3866(identity)	refseq:NP_009370.1|sgd:S000000030|ensemblfungi:YAL032C(gene)|ensemblfungi:YAL032C_mRNA(transcript)|go:"GO:0000350"(generation of catalytic spliceosome for second transesterification step)|go:"GO:0005634"(nucleus)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|interpro:IPR004015(SKIP/SNW)|interpro:IPR017862|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|dip:DIP-2774N|mint:P28004|sgd:YAL032C(identity)	-	-	crc64:FE5A724186D7FE84	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:WrZQBYQvrWcfrR5ojWXrXp6spPE9606	rogid:qoHF1UsO3k+JOTOfigSuy2P84/k559292	intact-crc:9C0D3C15BE37D4DF|rigid:4w+BxVSaSSy0ukWUMAf8EPr4mzM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P43355	uniprotkb:P28004	intact:EBI-740978|ensembl:ENSP00000349085|uniprotkb:O00346|uniprotkb:B2RC81	intact:EBI-20640|uniprotkb:D6VPI6|ensemblfungi:YAL032C	psi-mi:maga1_human(display_long)|uniprotkb:MAGE-1 antigen(gene name synonym)|uniprotkb:Antigen MZ2-E(gene name synonym)|uniprotkb:Cancer/testis antigen 1.1(gene name synonym)|uniprotkb:MAGEA1(gene name)|psi-mi:MAGEA1(display_short)|uniprotkb:MAGE1(gene name synonym)|uniprotkb:MAGE1A(gene name synonym)	psi-mi:prp45_yeast(display_long)|uniprotkb:YAL032C(locus name)|uniprotkb:PRP45(gene name)|psi-mi:PRP45(display_short)|uniprotkb:FUN20(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11524962|imex:IM-24995-276	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004979.3|ensembl:ENSG00000198681(gene)|ensembl:ENST00000356661(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|interpro:IPR002190(MAGE protein)|interpro:IPR021072|interpro:IPR030093|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|rcsb pdb:1W72|rcsb pdb:3BO8|dip:DIP-54794N|entrezgene/locuslink:4100(identity)	refseq:NP_009370.1|sgd:S000000030|ensemblfungi:YAL032C(gene)|ensemblfungi:YAL032C_mRNA(transcript)|go:"GO:0000350"(generation of catalytic spliceosome for second transesterification step)|go:"GO:0005634"(nucleus)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|interpro:IPR004015(SKIP/SNW)|interpro:IPR017862|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|dip:DIP-2774N|mint:P28004|sgd:YAL032C(identity)	-	crc64:544EEB1F9F4E9D33	crc64:FE5A724186D7FE84	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:6XW3mnTNM3yvOtXmiFbU8Uz3hjA9606	rogid:qoHF1UsO3k+JOTOfigSuy2P84/k559292	intact-crc:786ABE5472315612|rigid:atlGVCsRYtMXruwX/AYXgfjHlJs	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P28004	uniprotkb:Q8IYF3-3	intact:EBI-20640|uniprotkb:D6VPI6|ensemblfungi:YAL032C	intact:EBI-11523345|ensembl:ENSP00000363453	psi-mi:prp45_yeast(display_long)|uniprotkb:YAL032C(locus name)|uniprotkb:PRP45(gene name)|psi-mi:PRP45(display_short)|uniprotkb:FUN20(gene name synonym)	psi-mi:q8iyf3-3(display_long)|uniprotkb:TEX11(gene name)|psi-mi:TEX11(display_short)|uniprotkb:Protein ZIP4 homolog(gene name synonym)|uniprotkb:ZIP4(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11525016|imex:IM-24995-282	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009370.1|sgd:S000000030|ensemblfungi:YAL032C(gene)|ensemblfungi:YAL032C_mRNA(transcript)|go:"GO:0000350"(generation of catalytic spliceosome for second transesterification step)|go:"GO:0005634"(nucleus)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|interpro:IPR004015(SKIP/SNW)|interpro:IPR017862|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|dip:DIP-2774N|mint:P28004|sgd:YAL032C(identity)	ensembl:ENSG00000120498(gene)|ensembl:ENST00000374333(transcript)|intact:EBI-742397(isoform-parent)|uniprotkb:Q8IYF3-3(isoform-parent)|entrezgene/locuslink:56159(identity)	-	crc64:FE5A724186D7FE84	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:qoHF1UsO3k+JOTOfigSuy2P84/k559292	rogid:PUAMFmnm5ZV2rnJ1rhm9ZeRCixg9606	intact-crc:D9C34E5AC99D9726|rigid:bFlrER27s5qGZWGKEo74cSVGA2Y	false	-	sufficient binding region:9-925	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q5T124-6	uniprotkb:P28004	intact:EBI-11524408	intact:EBI-20640|uniprotkb:D6VPI6|ensemblfungi:YAL032C	psi-mi:q5t124-6(display_long)|uniprotkb:UBXN11(gene name)|psi-mi:UBXN11(display_short)|uniprotkb:Colorectal tumor-associated antigen COA-1(gene name synonym)|uniprotkb:SOC(gene name synonym)|uniprotkb:Socius(gene name synonym)|uniprotkb:UBX domain-containing protein 5(gene name synonym)|uniprotkb:UBXD5(gene name synonym)|uniprotkb:PP2243(orf name)	psi-mi:prp45_yeast(display_long)|uniprotkb:YAL032C(locus name)|uniprotkb:PRP45(gene name)|psi-mi:PRP45(display_short)|uniprotkb:FUN20(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11525007|imex:IM-24995-281	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-746004(isoform-parent)|uniprotkb:Q5T124-6(isoform-parent)|entrezgene/locuslink:91544(identity)	refseq:NP_009370.1|sgd:S000000030|ensemblfungi:YAL032C(gene)|ensemblfungi:YAL032C_mRNA(transcript)|go:"GO:0000350"(generation of catalytic spliceosome for second transesterification step)|go:"GO:0005634"(nucleus)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|interpro:IPR004015(SKIP/SNW)|interpro:IPR017862|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|dip:DIP-2774N|mint:P28004|sgd:YAL032C(identity)	-	-	crc64:FE5A724186D7FE84	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:1YSjG/p2ihcjl4P8KdPCaX2HxiY9606	rogid:qoHF1UsO3k+JOTOfigSuy2P84/k559292	intact-crc:95D02BC2D5319DF2|rigid:LrNsNOcmHu7Nauf8ed4RBHZX+Wg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q13422-7	uniprotkb:P28004	intact:EBI-11522367|ensembl:ENSP00000352123|ensembl:ENSP00000413025	intact:EBI-20640|uniprotkb:D6VPI6|ensemblfungi:YAL032C	psi-mi:q13422-7(display_long)|uniprotkb:IKZF1(gene name)|psi-mi:IKZF1(display_short)|uniprotkb:IK1(gene name synonym)|uniprotkb:IKAROS(gene name synonym)|uniprotkb:Ikaros family zinc finger protein 1(gene name synonym)|uniprotkb:LYF1(gene name synonym)|uniprotkb:Lymphoid transcription factor LyF-1(gene name synonym)|uniprotkb:ZNFN1A1(gene name synonym)	psi-mi:prp45_yeast(display_long)|uniprotkb:YAL032C(locus name)|uniprotkb:PRP45(gene name)|psi-mi:PRP45(display_short)|uniprotkb:FUN20(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11524980|imex:IM-24995-278	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-745305(isoform-parent)|ensembl:ENSG00000185811(gene)|ensembl:ENST00000359197(transcript)|ensembl:ENST00000439701(transcript)|uniprotkb:Q13422-7(isoform-parent)|entrezgene/locuslink:10320(identity)	refseq:NP_009370.1|sgd:S000000030|ensemblfungi:YAL032C(gene)|ensemblfungi:YAL032C_mRNA(transcript)|go:"GO:0000350"(generation of catalytic spliceosome for second transesterification step)|go:"GO:0005634"(nucleus)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|interpro:IPR004015(SKIP/SNW)|interpro:IPR017862|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|dip:DIP-2774N|mint:P28004|sgd:YAL032C(identity)	-	-	crc64:FE5A724186D7FE84	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:ou/ovXYoMneBNVp4pj38VxenfyY9606	rogid:qoHF1UsO3k+JOTOfigSuy2P84/k559292	intact-crc:7A0A4900F90E9F71|rigid:WMydF67ZCWFq4i6PYP0NLZP8YGw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P28004	uniprotkb:Q13643	intact:EBI-20640|uniprotkb:D6VPI6|ensemblfungi:YAL032C	intact:EBI-741101|ensembl:ENSP00000362107|uniprotkb:Q6I9T0|uniprotkb:Q9BVA2|uniprotkb:D3DPT6	psi-mi:prp45_yeast(display_long)|uniprotkb:YAL032C(locus name)|uniprotkb:PRP45(gene name)|psi-mi:PRP45(display_short)|uniprotkb:FUN20(gene name synonym)	psi-mi:fhl3_human(display_long)|uniprotkb:FHL3(gene name)|psi-mi:FHL3(display_short)|uniprotkb:SLIM2(gene name synonym)|uniprotkb:Skeletal muscle LIM-protein 2(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11524989|imex:IM-24995-279	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009370.1|sgd:S000000030|ensemblfungi:YAL032C(gene)|ensemblfungi:YAL032C_mRNA(transcript)|go:"GO:0000350"(generation of catalytic spliceosome for second transesterification step)|go:"GO:0005634"(nucleus)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|interpro:IPR004015(SKIP/SNW)|interpro:IPR017862|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|dip:DIP-2774N|mint:P28004|sgd:YAL032C(identity)	refseq:NP_004459.2|ensembl:ENSG00000183386(gene)|ensembl:ENST00000373016(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005925"(focal adhesion)|go:"GO:0007517"(muscle organ development)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0046872"(metal ion binding)|interpro:IPR001781(Zinc finger, LIM-type)|mint:Q13643|rcsb pdb:1WYH|rcsb pdb:2CUQ|rcsb pdb:2EHE|interpro:IPR037987|refseq:NP_001230807.1|dip:DIP-42030N|entrezgene/locuslink:2275(identity)	-	crc64:FE5A724186D7FE84	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:qoHF1UsO3k+JOTOfigSuy2P84/k559292	rogid:RAo+b/VgFSnHSbgR+zXuxJvypxM9606	intact-crc:07D13194D5AB8EBB|rigid:B/hjQikOusZuoTzjXLPHZWJuQHk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q5JR59-3	uniprotkb:P28004	intact:EBI-11522433|ensembl:ENSP00000370186	intact:EBI-20640|uniprotkb:D6VPI6|ensemblfungi:YAL032C	psi-mi:q5jr59-3(display_long)|uniprotkb:MTUS2(gene name)|psi-mi:MTUS2(display_short)|uniprotkb:CAZIP(gene name synonym)|uniprotkb:Cardiac zipper protein(gene name synonym)|uniprotkb:KIAA0774(gene name synonym)|uniprotkb:Microtubule plus-end tracking protein TIP150(gene name synonym)|uniprotkb:TIP150(gene name synonym)	psi-mi:prp45_yeast(display_long)|uniprotkb:YAL032C(locus name)|uniprotkb:PRP45(gene name)|psi-mi:PRP45(display_short)|uniprotkb:FUN20(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11524998|imex:IM-24995-280	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000132938(gene)|ensembl:ENST00000380808(transcript)|intact:EBI-742948(isoform-parent)|uniprotkb:Q5JR59-3(isoform-parent)|entrezgene/locuslink:23281(identity)	refseq:NP_009370.1|sgd:S000000030|ensemblfungi:YAL032C(gene)|ensemblfungi:YAL032C_mRNA(transcript)|go:"GO:0000350"(generation of catalytic spliceosome for second transesterification step)|go:"GO:0005634"(nucleus)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|interpro:IPR004015(SKIP/SNW)|interpro:IPR017862|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|dip:DIP-2774N|mint:P28004|sgd:YAL032C(identity)	-	isoform-comment:No experimental confirmation available.	crc64:FE5A724186D7FE84	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:npId9tC7VoLN/jteoBiRbSYChPs9606	rogid:qoHF1UsO3k+JOTOfigSuy2P84/k559292	intact-crc:6D808015713C3867|rigid:+4ZFzEaiSQIi/mKLMudoTNTyewE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8NHQ1	uniprotkb:P28004	intact:EBI-739624|ensembl:ENSP00000264982|ensembl:ENSP00000419231|uniprotkb:Q96B31|uniprotkb:Q9H2C3|uniprotkb:Q9H2Z1|uniprotkb:Q9H940|uniprotkb:D3DNE9|uniprotkb:B7Z5I8|uniprotkb:B7Z7E8|uniprotkb:F5GZX8	intact:EBI-20640|uniprotkb:D6VPI6|ensemblfungi:YAL032C	psi-mi:cep70_human(display_long)|uniprotkb:CEP70(gene name)|psi-mi:CEP70(display_short)|uniprotkb:BITE(gene name synonym)|uniprotkb:p10-binding protein(gene name synonym)	psi-mi:prp45_yeast(display_long)|uniprotkb:YAL032C(locus name)|uniprotkb:PRP45(gene name)|psi-mi:PRP45(display_short)|uniprotkb:FUN20(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11525036|imex:IM-24995-284	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114107(gene)|ensembl:ENST00000264982(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|interpro:IPR019734|interpro:IPR037692|mint:Q8NHQ1|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|ensembl:ENST00000484888(transcript)|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_077817.2|refseq:XP_016862764.1|refseq:NP_001275893.1|refseq:NP_001275894.1|refseq:NP_001275895.1|refseq:NP_001275896.1|refseq:NP_001307527.1|refseq:NP_001307529.1|entrezgene/locuslink:80321(identity)	refseq:NP_009370.1|sgd:S000000030|ensemblfungi:YAL032C(gene)|ensemblfungi:YAL032C_mRNA(transcript)|go:"GO:0000350"(generation of catalytic spliceosome for second transesterification step)|go:"GO:0005634"(nucleus)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|interpro:IPR004015(SKIP/SNW)|interpro:IPR017862|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|dip:DIP-2774N|mint:P28004|sgd:YAL032C(identity)	-	-	crc64:FE5A724186D7FE84	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:S4yveQWcvdVtAUX65gqrJ5Dv0Mc9606	rogid:qoHF1UsO3k+JOTOfigSuy2P84/k559292	intact-crc:5EDEEA897D28EC32|rigid:SN4sk0rmyaezL9EELRiB8gngOQ0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P28004	uniprotkb:Q8N6Y0	intact:EBI-20640|uniprotkb:D6VPI6|ensemblfungi:YAL032C	intact:EBI-739895|uniprotkb:Q8NBX7|uniprotkb:Q96KH3|uniprotkb:Q9BYI8|uniprotkb:A8K7L6|uniprotkb:B2RCR9|ensembl:ENSP00000252597	psi-mi:prp45_yeast(display_long)|uniprotkb:YAL032C(locus name)|uniprotkb:PRP45(gene name)|psi-mi:PRP45(display_short)|uniprotkb:FUN20(gene name synonym)	psi-mi:usbp1_human(display_long)|uniprotkb:USHBP1(gene name)|psi-mi:USHBP1(display_short)|uniprotkb:MCC-2(gene name synonym)|uniprotkb:AIE-75-binding protein(gene name synonym)|uniprotkb:AIEBP(gene name synonym)|uniprotkb:MCC2(gene name synonym)|uniprotkb:Mutated in colon cancer protein 2(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11525027|imex:IM-24995-283	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009370.1|sgd:S000000030|ensemblfungi:YAL032C(gene)|ensemblfungi:YAL032C_mRNA(transcript)|go:"GO:0000350"(generation of catalytic spliceosome for second transesterification step)|go:"GO:0005634"(nucleus)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|interpro:IPR004015(SKIP/SNW)|interpro:IPR017862|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|dip:DIP-2774N|mint:P28004|sgd:YAL032C(identity)	refseq:NP_001284632.1|refseq:NP_114147.2|refseq:NP_001308346.1|ensembl:ENSG00000130307(gene)|ensembl:ENST00000252597(transcript)|go:"GO:0030165"(PDZ domain binding)|interpro:IPR019536|interpro:IPR040171|entrezgene/locuslink:83878(identity)	-	crc64:FE5A724186D7FE84	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:qoHF1UsO3k+JOTOfigSuy2P84/k559292	rogid:vY1qx73Ju/z7WDu6k1kd10ZDVRo9606	intact-crc:794EEB5E85166E3D|rigid:58s9BfEOehK3LAa3Idmi3Xjo3vE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8TAP6	uniprotkb:P28004	intact:EBI-742887|ensembl:ENSP00000262127|uniprotkb:Q658N5|uniprotkb:Q9H9U7|uniprotkb:B0YJB2|uniprotkb:B4DXG5|uniprotkb:B4DZW1	intact:EBI-20640|uniprotkb:D6VPI6|ensemblfungi:YAL032C	psi-mi:cep76_human(display_long)|uniprotkb:CEP76(gene name)|psi-mi:CEP76(display_short)|uniprotkb:C18orf9(gene name synonym)	psi-mi:prp45_yeast(display_long)|uniprotkb:YAL032C(locus name)|uniprotkb:PRP45(gene name)|psi-mi:PRP45(display_short)|uniprotkb:FUN20(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11525045|imex:IM-24995-285	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_079175.2|ensembl:ENSG00000101624(gene)|ensembl:ENST00000262127(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0046599"(regulation of centriole replication)|interpro:IPR028926|interpro:IPR038765|mint:Q8TAP6|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_001258918.1|entrezgene/locuslink:79959(identity)	refseq:NP_009370.1|sgd:S000000030|ensemblfungi:YAL032C(gene)|ensemblfungi:YAL032C_mRNA(transcript)|go:"GO:0000350"(generation of catalytic spliceosome for second transesterification step)|go:"GO:0005634"(nucleus)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|interpro:IPR004015(SKIP/SNW)|interpro:IPR017862|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|dip:DIP-2774N|mint:P28004|sgd:YAL032C(identity)	-	-	crc64:FE5A724186D7FE84	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:fWzb8oIU35oVWomyDrf8u5sbxUk9606	rogid:qoHF1UsO3k+JOTOfigSuy2P84/k559292	intact-crc:32BAAEFFB54EA570|rigid:asauxzIqMwX/jnbHM8oNmdgnmJs	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P28004	uniprotkb:Q8WWB3	intact:EBI-20640|uniprotkb:D6VPI6|ensemblfungi:YAL032C	intact:EBI-740680|ensembl:ENSP00000361276|ensembl:ENSP00000361278|ensembl:ENSP00000402890|uniprotkb:Q5QP03|uniprotkb:Q5QP04|uniprotkb:Q6WNP4|uniprotkb:Q6ZU87|uniprotkb:A8K927	psi-mi:prp45_yeast(display_long)|uniprotkb:YAL032C(locus name)|uniprotkb:PRP45(gene name)|psi-mi:PRP45(display_short)|uniprotkb:FUN20(gene name synonym)	psi-mi:dydc1_human(display_long)|uniprotkb:DYDC1(gene name)|psi-mi:DYDC1(display_short)|uniprotkb:DPY30D1(gene name synonym)|uniprotkb:RSD9(orf name)|uniprotkb:RSD-9(orf name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11525054|imex:IM-24995-286	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009370.1|sgd:S000000030|ensemblfungi:YAL032C(gene)|ensemblfungi:YAL032C_mRNA(transcript)|go:"GO:0000350"(generation of catalytic spliceosome for second transesterification step)|go:"GO:0005634"(nucleus)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|interpro:IPR004015(SKIP/SNW)|interpro:IPR017862|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|dip:DIP-2774N|mint:P28004|sgd:YAL032C(identity)	refseq:NP_620167.1|ensembl:ENSG00000170788(gene)|ensembl:ENST00000372202(transcript)|ensembl:ENST00000372204(transcript)|ensembl:ENST00000421924(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0006348"|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|interpro:IPR007858(Dpy-30)|interpro:IPR037856|refseq:XP_011537636.1|refseq:XP_011537637.1|refseq:NP_001255982.1|refseq:XP_005269606.1|refseq:XP_005269607.1|entrezgene/locuslink:143241(identity)	-	crc64:FE5A724186D7FE84	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:qoHF1UsO3k+JOTOfigSuy2P84/k559292	rogid:W6GUazYFXZGHGijUBpAJ5GiRuXA9606	intact-crc:3E24B82B51E27D76|rigid:m+GJ+aeiVaLiiud/0VLVpK7jNIs	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P28004	uniprotkb:Q8WXE1-3	intact:EBI-20640|uniprotkb:D6VPI6|ensemblfungi:YAL032C	intact:EBI-11524582|ensembl:ENSP00000400930	psi-mi:prp45_yeast(display_long)|uniprotkb:YAL032C(locus name)|uniprotkb:PRP45(gene name)|psi-mi:PRP45(display_short)|uniprotkb:FUN20(gene name synonym)	psi-mi:q8wxe1-3(display_long)|uniprotkb:ATRIP(gene name)|psi-mi:ATRIP(display_short)|uniprotkb:AGS1(gene name synonym)|uniprotkb:ATM and Rad3-related-interacting protein(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11525063|imex:IM-24995-287	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009370.1|sgd:S000000030|ensemblfungi:YAL032C(gene)|ensemblfungi:YAL032C_mRNA(transcript)|go:"GO:0000350"(generation of catalytic spliceosome for second transesterification step)|go:"GO:0005634"(nucleus)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|interpro:IPR004015(SKIP/SNW)|interpro:IPR017862|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|dip:DIP-2774N|mint:P28004|sgd:YAL032C(identity)	intact:EBI-747353(isoform-parent)|ensembl:ENSG00000164053(gene)|ensembl:ENST00000412052(transcript)|entrezgene/locuslink:84126(identity)	-	crc64:FE5A724186D7FE84	isoform-comment:No experimental confirmation available.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:qoHF1UsO3k+JOTOfigSuy2P84/k559292	rogid:NKCjy1jGZEySEhUOf8rJ6h9pyxY9606	intact-crc:B52236E4E85FBC44|rigid:J70e7vmfBgj+wUTeeimePrYnIzM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9Y3Q8	uniprotkb:P28004	intact:EBI-739485|uniprotkb:A8MWR6|ensembl:ENSP00000300181|uniprotkb:A4D2C3|uniprotkb:D6W5V9	intact:EBI-20640|uniprotkb:D6VPI6|ensemblfungi:YAL032C	psi-mi:t22d4_human(display_long)|uniprotkb:TSC22D4(gene name)|psi-mi:TSC22D4(display_short)|uniprotkb:TILZ2(gene name synonym)|uniprotkb:TSC22-related-inducible leucine zipper protein 2(gene name synonym)|uniprotkb:Tsc-22-like protein THG-1(gene name synonym)|uniprotkb:THG1(gene name synonym)	psi-mi:prp45_yeast(display_long)|uniprotkb:YAL032C(locus name)|uniprotkb:PRP45(gene name)|psi-mi:PRP45(display_short)|uniprotkb:FUN20(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11525108|imex:IM-24995-292	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000166925(gene)|ensembl:ENST00000300181(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006970"(response to osmotic stress)|interpro:IPR000580(TSC-22 / Dip / Bun)|interpro:IPR042553|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|refseq:NP_112197.1|refseq:NP_001289972.1|entrezgene/locuslink:81628(identity)	refseq:NP_009370.1|sgd:S000000030|ensemblfungi:YAL032C(gene)|ensemblfungi:YAL032C_mRNA(transcript)|go:"GO:0000350"(generation of catalytic spliceosome for second transesterification step)|go:"GO:0005634"(nucleus)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|interpro:IPR004015(SKIP/SNW)|interpro:IPR017862|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|dip:DIP-2774N|mint:P28004|sgd:YAL032C(identity)	-	-	crc64:FE5A724186D7FE84	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:eL12cHY76zEPOXzT1HFKPSckS8Y9606	rogid:qoHF1UsO3k+JOTOfigSuy2P84/k559292	intact-crc:A625EE6DE9B96864|rigid:riVze4uPf7Sha0q+RYw99zeY8eI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P28004	uniprotkb:Q9UKT9	intact:EBI-20640|uniprotkb:D6VPI6|ensemblfungi:YAL032C	intact:EBI-747204|uniprotkb:Q8WWQ9|uniprotkb:Q8WWR0|uniprotkb:Q8WWR1|uniprotkb:Q8WWR2|uniprotkb:Q8WWR3|uniprotkb:Q8N574|uniprotkb:B4DVV5|uniprotkb:Q69BL6|uniprotkb:Q69BL7|uniprotkb:Q69BL8|uniprotkb:Q69BL9|uniprotkb:Q69BM0|uniprotkb:Q69BM1|uniprotkb:Q69BM2|uniprotkb:Q69BM3|uniprotkb:Q69BM5|ensembl:ENSP00000344544	psi-mi:prp45_yeast(display_long)|uniprotkb:YAL032C(locus name)|uniprotkb:PRP45(gene name)|psi-mi:PRP45(display_short)|uniprotkb:FUN20(gene name synonym)	psi-mi:ikzf3_human(display_long)|uniprotkb:ZNFN1A3(gene name synonym)|uniprotkb:Ikaros family zinc finger protein 3(gene name synonym)|uniprotkb:IKZF3(gene name)|psi-mi:IKZF3(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11525099|imex:IM-24995-291	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009370.1|sgd:S000000030|ensemblfungi:YAL032C(gene)|ensemblfungi:YAL032C_mRNA(transcript)|go:"GO:0000350"(generation of catalytic spliceosome for second transesterification step)|go:"GO:0005634"(nucleus)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|interpro:IPR004015(SKIP/SNW)|interpro:IPR017862|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|dip:DIP-2774N|mint:P28004|sgd:YAL032C(identity)	refseq:NP_001271443.1|refseq:NP_001271444.1|refseq:NP_036613.2|refseq:NP_899051.1|refseq:NP_899052.1|refseq:NP_899053.1|refseq:NP_899054.1|refseq:NP_899055.1|refseq:NP_001271445.1|refseq:NP_001244337.1|refseq:NP_001244338.1|refseq:NP_001244339.1|refseq:NP_001244340.1|refseq:NP_001244341.1|refseq:NP_001244342.1|refseq:NP_001244343.1|ensembl:ENSG00000161405(gene)|ensembl:ENST00000346872(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007498"(mesoderm development)|go:"GO:0009617"(response to bacterium)|go:"GO:0030888"(regulation of B cell proliferation)|go:"GO:0042113"(B cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045577"(regulation of B cell differentiation)|go:"GO:0045619"(regulation of lymphocyte differentiation)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|go:"GO:0046872"(metal ion binding)|dip:DIP-56975N|entrezgene/locuslink:22806(identity)	-	crc64:FE5A724186D7FE84	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:qoHF1UsO3k+JOTOfigSuy2P84/k559292	rogid:2Kp6LefSLfK5VIiE6DmQusFIfMY9606	intact-crc:F49F35E62629ED1B|rigid:v6leynU3zaB55LIQL3Ag/PFxtks	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96MT8-3	uniprotkb:P28004	intact:EBI-11522539|ensembl:ENSP00000507703|ensembl:ENSP00000328382|ensembl:ENSP00000506728|ensembl:ENSP00000506791|ensembl:ENSP00000506828|ensembl:ENSP00000507228	intact:EBI-20640|uniprotkb:D6VPI6|ensemblfungi:YAL032C	psi-mi:q96mt8-3(display_long)|uniprotkb:CEP63(gene name)|psi-mi:CEP63(display_short)	psi-mi:prp45_yeast(display_long)|uniprotkb:YAL032C(locus name)|uniprotkb:PRP45(gene name)|psi-mi:PRP45(display_short)|uniprotkb:FUN20(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11525072|imex:IM-24995-288	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-741977(isoform-parent)|ensembl:ENST00000332047(transcript)|ensembl:ENST00000682042(transcript)|ensembl:ENST00000682800(transcript)|ensembl:ENST00000682858(transcript)|ensembl:ENST00000683177(transcript)|ensembl:ENST00000683861(transcript)|ensembl:ENSG00000182923(gene)|uniprotkb:Q96MT8-3(isoform-parent)|entrezgene/locuslink:80254(identity)	refseq:NP_009370.1|sgd:S000000030|ensemblfungi:YAL032C(gene)|ensemblfungi:YAL032C_mRNA(transcript)|go:"GO:0000350"(generation of catalytic spliceosome for second transesterification step)|go:"GO:0005634"(nucleus)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|interpro:IPR004015(SKIP/SNW)|interpro:IPR017862|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|dip:DIP-2774N|mint:P28004|sgd:YAL032C(identity)	-	-	crc64:FE5A724186D7FE84	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:U0uvVcOCzA8Qp2cCB0ilixgd4Yc9606	rogid:qoHF1UsO3k+JOTOfigSuy2P84/k559292	intact-crc:3A978222E5E80185|rigid:EJ/r7IxMZYX8LJ5I6R1QwOOTrEs	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9NSC5	uniprotkb:P28004	intact:EBI-748420|uniprotkb:O14580|uniprotkb:O95350|uniprotkb:Q9NSB9|uniprotkb:Q9NSC0|intact:EBI-2557809|uniprotkb:E9PCW9|uniprotkb:Q9NSC1|intact:EBI-28972925|ensembl:ENSP00000376162|ensembl:ENSP00000439937|ensembl:ENSP00000446026|intact:EBI-10175777|uniprotkb:B2RA10	intact:EBI-20640|uniprotkb:D6VPI6|ensemblfungi:YAL032C	psi-mi:home3_human(display_long)|uniprotkb:HOMER3(gene name)|psi-mi:HOMER3(display_short)	psi-mi:prp45_yeast(display_long)|uniprotkb:YAL032C(locus name)|uniprotkb:PRP45(gene name)|psi-mi:PRP45(display_short)|uniprotkb:FUN20(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11525081|imex:IM-24995-289	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000221222|ensembl:ENSP00000221222|ensembl:ENSP00000376162|ensembl:ENST00000433218|ensembl:ENSP00000396154|ensembl:ENSP00000439937|ensembl:ENSP00000446026|ensembl:ENST00000594439|ensembl:ENSP00000471835|refseq:XP_006723006.1|refseq:XP_006723007.1|refseq:NP_001139193.1|refseq:NP_001139194.1|refseq:NP_004829.3|refseq:NP_001139196.1|ensembl:ENSG00000051128(gene)|ensembl:ENST00000392351(transcript)|ensembl:ENST00000539827(transcript)|ensembl:ENST00000542541(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006605"(protein targeting)|go:"GO:0007216"(G protein-coupled glutamate receptor signaling pathway)|go:"GO:0014069"(postsynaptic density)|go:"GO:0030425"(dendrite)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0035256"(G protein-coupled glutamate receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|go:"GO:2001256"(regulation of store-operated calcium entry)|interpro:IPR000697(EVH1)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR044100|mint:Q9NSC5|rcsb pdb:2P8V|rcsb pdb:3CVF|reactome:R-HSA-6794361|entrezgene/locuslink:9454(identity)	refseq:NP_009370.1|sgd:S000000030|ensemblfungi:YAL032C(gene)|ensemblfungi:YAL032C_mRNA(transcript)|go:"GO:0000350"(generation of catalytic spliceosome for second transesterification step)|go:"GO:0005634"(nucleus)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|interpro:IPR004015(SKIP/SNW)|interpro:IPR017862|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|dip:DIP-2774N|mint:P28004|sgd:YAL032C(identity)	-	-	crc64:FE5A724186D7FE84	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:U1y/y52nnf7zQUCNQlqk7JDgXi49606	rogid:qoHF1UsO3k+JOTOfigSuy2P84/k559292	intact-crc:CB461FD21BCB3EFA|rigid:Eduwq3iPRqhvty7rIjhzv5EAGG8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P28004	uniprotkb:Q9UDV6	intact:EBI-20640|uniprotkb:D6VPI6|ensemblfungi:YAL032C	intact:EBI-1640204|uniprotkb:Q13396|uniprotkb:Q8N664|uniprotkb:B2RCF4|ensembl:ENSP00000338572	psi-mi:prp45_yeast(display_long)|uniprotkb:YAL032C(locus name)|uniprotkb:PRP45(gene name)|psi-mi:PRP45(display_short)|uniprotkb:FUN20(gene name synonym)	psi-mi:zn212_human(display_long)|uniprotkb:ZNF212(gene name)|psi-mi:ZNF212(display_short)|uniprotkb:ZNFC150(gene name synonym)|uniprotkb:Zinc finger protein C2H2-150(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11525090|imex:IM-24995-290	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009370.1|sgd:S000000030|ensemblfungi:YAL032C(gene)|ensemblfungi:YAL032C_mRNA(transcript)|go:"GO:0000350"(generation of catalytic spliceosome for second transesterification step)|go:"GO:0005634"(nucleus)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|interpro:IPR004015(SKIP/SNW)|interpro:IPR017862|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|dip:DIP-2774N|mint:P28004|sgd:YAL032C(identity)	refseq:NP_036388.2|ensembl:ENSG00000170260(gene)|ensembl:ENST00000335870(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR022137|interpro:IPR036051|interpro:IPR036236|mint:Q9UDV6|reactome:R-HSA-212436|entrezgene/locuslink:7988(identity)	-	crc64:FE5A724186D7FE84	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:qoHF1UsO3k+JOTOfigSuy2P84/k559292	rogid:jZtScr5t/MR83+d1tdA9OiP4JCA9606	intact-crc:FEB2718AF961F1E9|rigid:JZrk/DQKgLpkDiy4/hqJoGL3uvo	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P29461	uniprotkb:P51116	intact:EBI-14188|ensemblfungi:YOR208W|uniprotkb:D6W2R4	intact:EBI-740459|uniprotkb:Q8WUM2|uniprotkb:Q86V09|uniprotkb:B2R9M2|uniprotkb:D3DTQ1|ensembl:ENSP00000250113	psi-mi:ptp2_yeast(display_long)|uniprotkb:Protein-tyrosine phosphatase 2(gene name synonym)|uniprotkb:PTP2(gene name)|psi-mi:PTP2(display_short)|uniprotkb:YOR208W(locus name)	psi-mi:fxr2_human(display_long)|uniprotkb:FXR2(gene name)|psi-mi:FXR2(display_short)|uniprotkb:FMR1L2(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11525153|imex:IM-24995-297	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005734|ensemblfungi:YOR208W(gene)|ensemblfungi:YOR208W_mRNA(transcript)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0043937"(regulation of sporulation)|go:"GO:0051457"(maintenance of protein location in nucleus)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|refseq:NP_014851.3|dip:DIP-2369N|sgd:YOR208W(identity)	interpro:IPR004087(K Homology)|refseq:NP_004851.2|ensembl:ENSG00000129245(gene)|ensembl:ENST00000250113(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0044326"(dendritic spine neck)|go:"GO:0045182"(translation regulator activity)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0098793"(presynapse)|go:"GO:1902737"(dendritic filopodium)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|interpro:IPR004088(K Homology, type 1)|interpro:IPR008395(Agenet)|interpro:IPR022034|interpro:IPR032172|interpro:IPR036612|interpro:IPR040148|interpro:IPR040472|interpro:IPR041560|mint:P51116|rcsb pdb:3H8Z|entrezgene/locuslink:9513(identity)	-	crc64:1033D2F0AA23BD35	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:y6lL7sE5o4uuIJ2YtaKCUzxz8o0559292	rogid:NnYgyzD2NRGIO1ZHukr5qy44qRE9606	intact-crc:6D35776A3EAE49BA|rigid:B5gDZeiWjPzPEo5bLYrloAF5b10	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P28777	uniprotkb:Q15025	intact:EBI-2906|uniprotkb:D6VU01|ensemblfungi:YGL148W	intact:EBI-357849|uniprotkb:A4F1W8|uniprotkb:O76008|uniprotkb:Q96EL9|uniprotkb:Q99833|uniprotkb:Q9H1J3|uniprotkb:B7Z699|uniprotkb:Q6N077|ensembl:ENSP00000317891|ensembl:ENSP00000428187|ensembl:ENSP00000430760|uniprotkb:A4F1W9|uniprotkb:A4F1X2|uniprotkb:A4F1X4|uniprotkb:A4F1X5|uniprotkb:A4F1X6|uniprotkb:A4F1X7|uniprotkb:A4F1X9|uniprotkb:E7EPY1|uniprotkb:E7ET96|uniprotkb:Q05KP3|uniprotkb:Q05KP4	psi-mi:aroc_yeast(display_long)|uniprotkb:ARO2(gene name)|psi-mi:ARO2(display_short)|uniprotkb:5-enolpyruvylshikimate-3-phosphate phospholyase(gene name synonym)|uniprotkb:YGL148W(locus name)	psi-mi:tnip1_human(display_long)|uniprotkb:TNIP1(gene name)|psi-mi:TNIP1(display_short)|uniprotkb:KIAA0113(gene name synonym)|uniprotkb:NAF1(gene name synonym)|uniprotkb:Nef-associated factor 1(gene name synonym)|uniprotkb:HIV-1 Nef-interacting protein(gene name synonym)|uniprotkb:Virion-associated nuclear shuttling protein(gene name synonym)|uniprotkb:Nip40-1(gene name synonym)|uniprotkb:A20-binding inhibitor of NF-kappa-B activation 1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11525144|imex:IM-24995-296	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011367.1|sgd:S000003116|dip:DIP-4219N|ensemblfungi:YGL148W(gene)|ensemblfungi:YGL148W_mRNA(transcript)|go:"GO:0004107"(chorismate synthase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008652"(cellular amino acid biosynthetic process)|go:"GO:0009073"(aromatic amino acid family biosynthetic process)|go:"GO:0009423"(chorismate biosynthetic process)|go:"GO:0010181"(FMN binding)|go:"GO:0042602"("riboflavin reductase (NADPH) activity")|interpro:IPR000453(Chorismate synthase)|interpro:IPR020541|interpro:IPR035904|rcsb pdb:1R52|rcsb pdb:1R53|sgd:YGL148W(identity)	refseq:NP_006049.3|refseq:NP_001239319.1|refseq:NP_001239320.1|refseq:NP_001239321.1|refseq:NP_001239322.1|refseq:NP_001245383.1|dip:DIP-27577N|refseq:NP_001239315.1|ensembl:ENSG00000145901(gene)|ensembl:ENST00000315050(transcript)|ensembl:ENST00000521591(transcript)|ensembl:ENST00000522226(transcript)|go:"GO:0002755"(MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0006952"(defense response)|go:"GO:0006954"(inflammatory response)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0009101"(glycoprotein biosynthetic process)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0085032"(modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade)|go:"GO:1903003"(positive regulation of protein deubiquitination)|interpro:IPR033372|mint:Q15025|reactome:R-HSA-5689896|go:"GO:0051019"(mitogen-activated protein kinase binding)|refseq:NP_001239314.1|refseq:NP_001245384.1|refseq:NP_001245385.1|refseq:XP_006714814.1|refseq:XP_006714815.1|entrezgene/locuslink:10318(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:JKW/ZDgiD3nPihuzkWGFypk8hlA559292	rogid:16Vjb5CuGTAbW2M22qbCxgXtV1o9606	intact-crc:8786CE4DFC872E78|rigid:xb67E17xpRCwxPHLuS+ViVrLr2Y	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P28004	uniprotkb:Q9Y6D9	intact:EBI-20640|uniprotkb:D6VPI6|ensemblfungi:YAL032C	intact:EBI-742610|uniprotkb:B3KR41|uniprotkb:Q9UNH0|uniprotkb:Q13312|uniprotkb:Q75MI0|uniprotkb:Q86UM4|ensembl:ENSP00000265854|ensembl:ENSP00000382562|ensembl:ENSP00000385334	psi-mi:prp45_yeast(display_long)|uniprotkb:YAL032C(locus name)|uniprotkb:PRP45(gene name)|psi-mi:PRP45(display_short)|uniprotkb:FUN20(gene name synonym)	psi-mi:md1l1_human(display_long)|uniprotkb:Mitotic arrest deficient 1-like protein 1(gene name synonym)|uniprotkb:Mitotic checkpoint MAD1 protein homolog(gene name synonym)|uniprotkb:Tax-binding protein 181(gene name synonym)|uniprotkb:MAD1L1(gene name)|psi-mi:MAD1L1(display_short)|uniprotkb:MAD1(gene name synonym)|uniprotkb:TXBP181(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11525117|imex:IM-24995-293	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009370.1|sgd:S000000030|ensemblfungi:YAL032C(gene)|ensemblfungi:YAL032C_mRNA(transcript)|go:"GO:0000350"(generation of catalytic spliceosome for second transesterification step)|go:"GO:0005634"(nucleus)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|interpro:IPR004015(SKIP/SNW)|interpro:IPR017862|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|dip:DIP-2774N|mint:P28004|sgd:YAL032C(identity)	refseq:NP_001013858.1|refseq:NP_001013859.1|refseq:NP_003541.2|refseq:NP_001291452.1|refseq:NP_001291453.1|ensembl:ENSG00000002822(gene)|ensembl:ENST00000265854(transcript)|go:"GO:0090235"(regulation of metaphase plate congression)|go:"GO:1902426"(deactivation of mitotic spindle assembly checkpoint)|interpro:IPR008672(Mitotic checkpoint)|mint:Q9Y6D9|rcsb pdb:1GO4|rcsb pdb:4DZO|rcsb pdb:7B1F|rcsb pdb:7B1H|rcsb pdb:7B1J|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|ensembl:ENST00000399654(transcript)|ensembl:ENST00000406869(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043515"(kinetochore binding)|go:"GO:0044615"(nuclear pore nuclear basket)|go:"GO:0048538"(thymus development)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0072686"(mitotic spindle)|refseq:XP_005249934.1|dip:DIP-29654N|entrezgene/locuslink:8379(identity)	-	crc64:FE5A724186D7FE84	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:qoHF1UsO3k+JOTOfigSuy2P84/k559292	rogid:9CcqpZlN0IgqC939rIo7vNgOvLQ9606	intact-crc:BC3F418F452E64CA|rigid:kbuda1h/jrILQ/THd5wtekEKM/4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P14136	uniprotkb:P28272	intact:EBI-744302|uniprotkb:Q53H98|uniprotkb:Q5D055|uniprotkb:Q6ZQS3|uniprotkb:Q7Z5J6|uniprotkb:Q7Z5J7|uniprotkb:Q96KS4|uniprotkb:Q96P18|uniprotkb:Q9UFD0|uniprotkb:B2RD44|uniprotkb:D3DX59|intact:EBI-3909365|uniprotkb:E9PAX3|ensembl:ENSP00000466598|uniprotkb:A7REI1	intact:EBI-14386|uniprotkb:Q2XN75|uniprotkb:Q70DC7|uniprotkb:D6VWY7|ensemblfungi:YKL216W	psi-mi:gfap_human(display_long)|uniprotkb:GFAP(gene name)|psi-mi:GFAP(display_short)	psi-mi:pyrd_yeast(display_long)|uniprotkb:YKL216W(locus name)|uniprotkb:URA1(gene name)|psi-mi:URA1(display_short)|uniprotkb:Dihydroorotate oxidase(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11525126|imex:IM-24995-294	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001124491.1|refseq:NP_001229305.1|refseq:NP_002046.1|ensembl:ENSG00000131095(gene)|ensembl:ENST00000588735(transcript)|go:"GO:0005178"(integrin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0009611"(response to wounding)|go:"GO:0010467"(gene expression)|go:"GO:0010625"(positive regulation of Schwann cell proliferation)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0014002"(astrocyte development)|go:"GO:0019900"(kinase binding)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0031102"(neuron projection regeneration)|go:"GO:0042802"(identical protein binding)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0044297"(cell body)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0051580"(regulation of neurotransmitter uptake)|go:"GO:0060020"(Bergmann glial cell differentiation)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0070779"(D-aspartate import across plasma membrane)|go:"GO:0097450"(astrocyte end-foot)|go:"GO:0098574"(cytoplasmic side of lysosomal membrane)|go:"GO:1904714"(regulation of chaperone-mediated autophagy)|interpro:IPR006821(Intermediate filament, DNA-binding region)|interpro:IPR018039|interpro:IPR027701|interpro:IPR039008|mint:P14136|rcsb pdb:6A9P|reactome:R-HSA-1251985|reactome:R-HSA-9613829|entrezgene/locuslink:2670(identity)	interpro:IPR023359|interpro:IPR024920|interpro:IPR033886|ensemblfungi:YKL216W(gene)|ensemblfungi:YKL216W_mRNA(transcript)|go:"GO:0004152"(dihydroorotate dehydrogenase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006207"('de novo' pyrimidine nucleobase biosynthetic process)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0044205"('de novo' UMP biosynthetic process)|go:"GO:1990663"("dihydroorotate dehydrogenase (fumarate) activity")|interpro:IPR001295(Dihydroorotate dehydrogenase, core)|interpro:IPR005720(Dihydroorotate dehydrogenase, class 1, core)|interpro:IPR012135(Dihydroorotate dehydrogenase, classes 1 and 2)|interpro:IPR013785(Aldolase-type TIM barrel)|refseq:NP_012706.1|sgd:S000001699|mint:P28272|dip:DIP-6573N|sgd:YKL216W(identity)	-	-	crc64:0F1FF9BDA7F8D68E	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Pz4JW0WjMjBYILTDSX9jUmMqWhg9606	rogid:EXmeAujwfMfvIaNkgvsl3YgWvPs559292	intact-crc:8065C89F79299184|rigid:AAroZq4KgO2UidBnxyZ6aHWVpTA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P28496	uniprotkb:Q8N6L0	intact:EBI-26585|uniprotkb:D6VXS8|ensemblfungi:YKL008C	intact:EBI-749265|uniprotkb:Q96MC3|ensembl:ENSP00000404220	psi-mi:lac1_yeast(display_long)|uniprotkb:LAC1(gene name)|psi-mi:LAC1(display_short)|uniprotkb:DGT1(gene name synonym)|uniprotkb:Very-long-chain ceramide synthase LAC1(gene name synonym)|uniprotkb:YKL156(orf name)|uniprotkb:YKL008C(locus name)	psi-mi:kash5_human(display_long)|uniprotkb:KASH5(gene name)|psi-mi:KASH5(display_short)|uniprotkb:CCDC155(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 155(gene name synonym)|uniprotkb:KASH domain-containing protein 5(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11525135|imex:IM-24995-295	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000001491|refseq:NP_012917.3|mint:P28496|dip:DIP-4348N|ensemblfungi:YKL008C(gene)|ensemblfungi:YKL008C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016410"(N-acyltransferase activity)|go:"GO:0034399"(nuclear periphery)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:0050291"(sphingosine N-acyltransferase activity)|go:"GO:0061576"(acyl-CoA ceramide synthase complex)|interpro:IPR006634(TRAM, LAG1 and CLN8 homology)|interpro:IPR013599(TRAM1-like protein)|interpro:IPR016439(Longevity assurance, LAG1/LAC1)|reactome:R-SCE-1660661|sgd:YKL008C(identity)	refseq:NP_653289.3|ensembl:ENSG00000161609(gene)|ensembl:ENST00000447857(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034397"(telomere localization)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051225"(spindle assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0090172"(microtubule cytoskeleton organization involved in homologous chromosome segregation)|go:"GO:0090220"(chromosome localization to nuclear envelope involved in homologous chromosome segregation)|go:"GO:0090619"(meiotic spindle pole)|interpro:IPR011992(EF-Hand type)|interpro:IPR028168|interpro:IPR028170|interpro:IPR039508|mint:Q8N6L0|rcsb pdb:6R2I|rcsb pdb:6WMF|entrezgene/locuslink:147872(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:gqRCCAHQcrRAHNO+R2LkQOzJ0mg559292	rogid:Wl9L7AcvDHCZuKjYLn8QgGIbZTc9606	intact-crc:9B2586E2ABD915A8|rigid:uxF2JNsk6pUSjMh4HBozlamYkDE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P29703	uniprotkb:A0A087X1U9	intact:EBI-14814|uniprotkb:D6VXR6|ensemblfungi:YKL019W	intact:EBI-11525184|ensembl:ENSP00000484475	psi-mi:fnta_yeast(display_long)|uniprotkb:YKL019W(locus name)|uniprotkb:RAM2(gene name)|psi-mi:RAM2(display_short)|uniprotkb:CAAX farnesyltransferase subunit alpha(gene name synonym)|uniprotkb:Ras proteins prenyltransferase subunit alpha(gene name synonym)|uniprotkb:FTase-alpha(gene name synonym)|uniprotkb:Type I protein geranyl-geranyltransferase subunit alpha(gene name synonym)	psi-mi:a0a087x1u9_human(display_long)|uniprotkb:GAK(gene name)|psi-mi:GAK(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11525188|imex:IM-24995-300	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000001502|refseq:NP_012906.3|go:"GO:0004662"(CAAX-protein geranylgeranyltransferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005953"(CAAX-protein geranylgeranyltransferase complex)|go:"GO:0005965"(protein farnesyltransferase complex)|go:"GO:0007323"(peptide pheromone maturation)|go:"GO:0018343"(protein farnesylation)|go:"GO:0018344"(protein geranylgeranylation)|interpro:IPR002088(Protein prenyltransferase, alpha subunit)|reactome:R-SCE-9648002|ensemblfungi:YKL019W(gene)|ensemblfungi:YKL019W_mRNA(transcript)|go:"GO:0004660"(protein farnesyltransferase activity)|go:"GO:0004661"(protein geranylgeranyltransferase activity)|dip:DIP-1233N|mint:P29703|sgd:YKL019W(identity)	ensembl:ENSG00000178950(gene)|ensembl:ENST00000618573(transcript)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR036869|entrezgene/locuslink:2580(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:u2rtpSuSW9Zd8LHWmniip7r5Ycs559292	rogid:9cLiPH0B6Uj9kREXyEJ+0f2ZQWw9606	intact-crc:4A2B378C03CFEB6C|rigid:3E6Ybvs/yLKLs7QpduyvkOxXCSA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96KN7-4	uniprotkb:P29461	intact:EBI-11525164|ensembl:ENSP00000372391	intact:EBI-14188|ensemblfungi:YOR208W|uniprotkb:D6W2R4	psi-mi:q96kn7-4(display_long)|uniprotkb:RPGRIP1(gene name)|psi-mi:RPGRIP1(display_short)	psi-mi:ptp2_yeast(display_long)|uniprotkb:Protein-tyrosine phosphatase 2(gene name synonym)|uniprotkb:PTP2(gene name)|psi-mi:PTP2(display_short)|uniprotkb:YOR208W(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11525162|imex:IM-24995-298	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-1050213(isoform-parent)|ensembl:ENSG00000092200(gene)|ensembl:ENST00000382933(transcript)|uniprotkb:Q96KN7-4(isoform-parent)|entrezgene/locuslink:57096(identity)	sgd:S000005734|ensemblfungi:YOR208W(gene)|ensemblfungi:YOR208W_mRNA(transcript)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0043937"(regulation of sporulation)|go:"GO:0051457"(maintenance of protein location in nucleus)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|refseq:NP_014851.3|dip:DIP-2369N|sgd:YOR208W(identity)	-	-	crc64:1033D2F0AA23BD35	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Xy0433uM/nWhWLM/EsfESPJDIy49606	rogid:y6lL7sE5o4uuIJ2YtaKCUzxz8o0559292	intact-crc:2037F882207A4E23|rigid:sWHPGmW1pLVHtqfUvOASr//pG4M	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P29703	uniprotkb:Q8N5R6	intact:EBI-14814|uniprotkb:D6VXR6|ensemblfungi:YKL019W	intact:EBI-740841|intact:EBI-953781|uniprotkb:B3KQ49|uniprotkb:A8K3U4|uniprotkb:A8MPQ6|uniprotkb:A8MV61|uniprotkb:A8MVU9|uniprotkb:Q9H5Q6|uniprotkb:Q8TAX6|intact:EBI-2320546|intact:EBI-11522976	psi-mi:fnta_yeast(display_long)|uniprotkb:YKL019W(locus name)|uniprotkb:RAM2(gene name)|psi-mi:RAM2(display_short)|uniprotkb:CAAX farnesyltransferase subunit alpha(gene name synonym)|uniprotkb:Ras proteins prenyltransferase subunit alpha(gene name synonym)|uniprotkb:FTase-alpha(gene name synonym)|uniprotkb:Type I protein geranyl-geranyltransferase subunit alpha(gene name synonym)	psi-mi:ccd33_human(display_long)|uniprotkb:CCDC33(gene name)|psi-mi:CCDC33(display_short)|uniprotkb:Cancer/testis antigen 61(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11525175|imex:IM-24995-299	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000001502|refseq:NP_012906.3|go:"GO:0004662"(CAAX-protein geranylgeranyltransferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005953"(CAAX-protein geranylgeranyltransferase complex)|go:"GO:0005965"(protein farnesyltransferase complex)|go:"GO:0007323"(peptide pheromone maturation)|go:"GO:0018343"(protein farnesylation)|go:"GO:0018344"(protein geranylgeranylation)|interpro:IPR002088(Protein prenyltransferase, alpha subunit)|reactome:R-SCE-9648002|ensemblfungi:YKL019W(gene)|ensemblfungi:YKL019W_mRNA(transcript)|go:"GO:0004660"(protein farnesyltransferase activity)|go:"GO:0004661"(protein geranylgeranyltransferase activity)|dip:DIP-1233N|mint:P29703|sgd:YKL019W(identity)	refseq:NP_079331.3|interpro:IPR000008(C2 calcium-dependent membrane targeting)|go:"GO:0005777"(peroxisome)|refseq:NP_001274110.1|refseq:NP_877592.2|mint:Q8N5R6|interpro:IPR035892|interpro:IPR039889|entrezgene/locuslink:80125(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2021/11/30	rogid:u2rtpSuSW9Zd8LHWmniip7r5Ycs559292	rogid:eEIn7pQyfdHWx8TeLJpYy0i/gww9606	intact-crc:338897EC400F400E|rigid:eNKRXOiTEKxKnSyeUuxyrUsxuiE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P37198	uniprotkb:P31384	intact:EBI-347978|intact:EBI-28983799|ensembl:ENSP00000305503|ensembl:ENSP00000407331|ensembl:ENSP00000471191|ensembl:ENSP00000473192|uniprotkb:Q6GTM2|uniprotkb:Q503A4|uniprotkb:Q96C43|uniprotkb:Q9NSL1|uniprotkb:B3KWU5	intact:EBI-4396|uniprotkb:D6VPJ7|ensemblfungi:YAL021C	psi-mi:nup62_human(display_long)|uniprotkb:NUP62(gene name)|psi-mi:NUP62(display_short)|uniprotkb:62 kDa nucleoporin(gene name synonym)|uniprotkb:Nucleoporin Nup62(gene name synonym)	psi-mi:ccr4_yeast(display_long)|uniprotkb:CCR4(gene name)|psi-mi:CCR4(display_short)|uniprotkb:Carbon catabolite repressor protein 4(gene name synonym)|uniprotkb:Cytoplasmic deadenylase(gene name synonym)|uniprotkb:Glucose-repressible alcohol dehydrogenase transcriptional effector(gene name synonym)|uniprotkb:FUN27(orf name)|uniprotkb:YAL021C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11525237|imex:IM-24995-305	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_714941.1|ensembl:ENSG00000213024(gene)|ensembl:ENST00000352066(transcript)|ensembl:ENST00000422090(transcript)|ensembl:ENST00000596217(transcript)|ensembl:ENST00000597029(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005642"(annulate lamellae)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007100"(mitotic centrosome separation)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007569"(cell aging)|go:"GO:0008219"(cell death)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0003682"(chromatin binding)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0019894"(kinesin binding)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042306"(regulation of protein import into nucleus)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043069"(negative regulation of programmed cell death)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045742"(positive regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046578"(regulation of Ras protein signal transduction)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0046601"(positive regulation of centriole replication)|go:"GO:0051028"(mRNA transport)|go:"GO:0051425"(PTB domain binding)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0072686"(mitotic spindle)|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|go:"GO:0090543"(Flemming body)|go:"GO:0098534"(centriole assembly)|go:"GO:1903438"(positive regulation of mitotic cytokinetic process)|go:"GO:1904781"(positive regulation of protein localization to centrosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR007758(Nucleoporin, Nsp1-like, C-terminal)|interpro:IPR026010|interpro:IPR033072|mint:P37198|rcsb pdb:2H4D|rcsb pdb:5IJN|rcsb pdb:5IJO|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|refseq:NP_714940.1|refseq:NP_001180286.1|refseq:NP_036478.2|refseq:NP_057637.2|ensembl:ENSP00000305503|ensembl:ENSP00000407331|ensembl:ENSP00000471191|ensembl:ENSP00000473192|dip:DIP-29749N|entrezgene/locuslink:23636(identity)	refseq:NP_009381.1|sgd:S000000019|dip:DIP-2522N|mint:P31384|ensemblfungi:YAL021C(gene)|ensemblfungi:YAL021C_mRNA(transcript)|go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0004535"("poly(A)-specific ribonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0007089"(traversing start control point of mitotic cell cycle)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0046872"(metal ion binding)|go:"GO:0048478"(replication fork protection)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR005135(Endonuclease/exonuclease/phosphatase)|interpro:IPR025875|interpro:IPR032675|interpro:IPR036691|rcsb pdb:4B8C|sgd:YAL021C(identity)	-	-	crc64:5CDB2E8FEDDBEF6F	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:v7mvKvTtVEnLMwcpUZIcdAzge009606	rogid:f5gxp32WdxKuHQnE8O9/EhhA3Gw559292	intact-crc:476B30FF84B02D21|rigid:LxPYRKS68Nq0z2/lCQwYo7kiCB4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P31384	uniprotkb:Q96IQ6	intact:EBI-4396|uniprotkb:D6VPJ7|ensemblfungi:YAL021C	intact:EBI-10295632|intact:EBI-11525227	psi-mi:ccr4_yeast(display_long)|uniprotkb:CCR4(gene name)|psi-mi:CCR4(display_short)|uniprotkb:Carbon catabolite repressor protein 4(gene name synonym)|uniprotkb:Cytoplasmic deadenylase(gene name synonym)|uniprotkb:Glucose-repressible alcohol dehydrogenase transcriptional effector(gene name synonym)|uniprotkb:FUN27(orf name)|uniprotkb:YAL021C(locus name)	psi-mi:q96iq6_human(display_long)|uniprotkb:CCR4-associated factor 1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11525225|imex:IM-24995-304	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009381.1|sgd:S000000019|dip:DIP-2522N|mint:P31384|ensemblfungi:YAL021C(gene)|ensemblfungi:YAL021C_mRNA(transcript)|go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0004535"("poly(A)-specific ribonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0007089"(traversing start control point of mitotic cell cycle)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0046872"(metal ion binding)|go:"GO:0048478"(replication fork protection)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR005135(Endonuclease/exonuclease/phosphatase)|interpro:IPR025875|interpro:IPR032675|interpro:IPR036691|rcsb pdb:4B8C|sgd:YAL021C(identity)	interpro:IPR039636|interpro:IPR039637|refseq:NP_001309019.1|refseq:NP_001309020.1|refseq:NP_001309021.1|refseq:NP_001309022.1|interpro:IPR006941(Ribonuclease CAF1)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|refseq:NP_001309023.1|refseq:NP_001309024.1|refseq:NP_001309025.1|refseq:NP_001309026.1|refseq:NP_037486.2|go:"GO:0003676"(nucleic acid binding)|go:"GO:0004535"("poly(A)-specific ribonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006417"(regulation of translation)|go:"GO:0030014"(CCR4-NOT complex)|interpro:IPR036397|entrezgene/locuslink:29883(identity)	-	crc64:5CDB2E8FEDDBEF6F	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/17	rogid:f5gxp32WdxKuHQnE8O9/EhhA3Gw559292	rogid:nAvs1jhkGYxf7NZ456rj5p+imsI9606	intact-crc:FEFD5634E7050213|rigid:1icdiwmRVXf6zQNT9XI8W2lxTWU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q15025	uniprotkb:P29703	intact:EBI-357849|uniprotkb:A4F1W8|uniprotkb:O76008|uniprotkb:Q96EL9|uniprotkb:Q99833|uniprotkb:Q9H1J3|uniprotkb:B7Z699|uniprotkb:Q6N077|ensembl:ENSP00000317891|ensembl:ENSP00000428187|ensembl:ENSP00000430760|uniprotkb:A4F1W9|uniprotkb:A4F1X2|uniprotkb:A4F1X4|uniprotkb:A4F1X5|uniprotkb:A4F1X6|uniprotkb:A4F1X7|uniprotkb:A4F1X9|uniprotkb:E7EPY1|uniprotkb:E7ET96|uniprotkb:Q05KP3|uniprotkb:Q05KP4	intact:EBI-14814|uniprotkb:D6VXR6|ensemblfungi:YKL019W	psi-mi:tnip1_human(display_long)|uniprotkb:TNIP1(gene name)|psi-mi:TNIP1(display_short)|uniprotkb:KIAA0113(gene name synonym)|uniprotkb:NAF1(gene name synonym)|uniprotkb:Nef-associated factor 1(gene name synonym)|uniprotkb:HIV-1 Nef-interacting protein(gene name synonym)|uniprotkb:Virion-associated nuclear shuttling protein(gene name synonym)|uniprotkb:Nip40-1(gene name synonym)|uniprotkb:A20-binding inhibitor of NF-kappa-B activation 1(gene name synonym)	psi-mi:fnta_yeast(display_long)|uniprotkb:YKL019W(locus name)|uniprotkb:RAM2(gene name)|psi-mi:RAM2(display_short)|uniprotkb:CAAX farnesyltransferase subunit alpha(gene name synonym)|uniprotkb:Ras proteins prenyltransferase subunit alpha(gene name synonym)|uniprotkb:FTase-alpha(gene name synonym)|uniprotkb:Type I protein geranyl-geranyltransferase subunit alpha(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11525197|imex:IM-24995-301	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006049.3|refseq:NP_001239319.1|refseq:NP_001239320.1|refseq:NP_001239321.1|refseq:NP_001239322.1|refseq:NP_001245383.1|dip:DIP-27577N|refseq:NP_001239315.1|ensembl:ENSG00000145901(gene)|ensembl:ENST00000315050(transcript)|ensembl:ENST00000521591(transcript)|ensembl:ENST00000522226(transcript)|go:"GO:0002755"(MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0006952"(defense response)|go:"GO:0006954"(inflammatory response)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0009101"(glycoprotein biosynthetic process)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0085032"(modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade)|go:"GO:1903003"(positive regulation of protein deubiquitination)|interpro:IPR033372|mint:Q15025|reactome:R-HSA-5689896|go:"GO:0051019"(mitogen-activated protein kinase binding)|refseq:NP_001239314.1|refseq:NP_001245384.1|refseq:NP_001245385.1|refseq:XP_006714814.1|refseq:XP_006714815.1|entrezgene/locuslink:10318(identity)	sgd:S000001502|refseq:NP_012906.3|go:"GO:0004662"(CAAX-protein geranylgeranyltransferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005953"(CAAX-protein geranylgeranyltransferase complex)|go:"GO:0005965"(protein farnesyltransferase complex)|go:"GO:0007323"(peptide pheromone maturation)|go:"GO:0018343"(protein farnesylation)|go:"GO:0018344"(protein geranylgeranylation)|interpro:IPR002088(Protein prenyltransferase, alpha subunit)|reactome:R-SCE-9648002|ensemblfungi:YKL019W(gene)|ensemblfungi:YKL019W_mRNA(transcript)|go:"GO:0004660"(protein farnesyltransferase activity)|go:"GO:0004661"(protein geranylgeranyltransferase activity)|dip:DIP-1233N|mint:P29703|sgd:YKL019W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:16Vjb5CuGTAbW2M22qbCxgXtV1o9606	rogid:u2rtpSuSW9Zd8LHWmniip7r5Ycs559292	intact-crc:D13CEF07AD5C8314|rigid:sQJPT1NPCq43/Y+YRi9FtfmfISo	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P29703	uniprotkb:Q8NA61-2	intact:EBI-14814|uniprotkb:D6VXR6|ensemblfungi:YKL019W	intact:EBI-11524851|ensembl:ENSP00000368249|ensembl:ENSP00000480148	psi-mi:fnta_yeast(display_long)|uniprotkb:YKL019W(locus name)|uniprotkb:RAM2(gene name)|psi-mi:RAM2(display_short)|uniprotkb:CAAX farnesyltransferase subunit alpha(gene name synonym)|uniprotkb:Ras proteins prenyltransferase subunit alpha(gene name synonym)|uniprotkb:FTase-alpha(gene name synonym)|uniprotkb:Type I protein geranyl-geranyltransferase subunit alpha(gene name synonym)	psi-mi:q8na61-2(display_long)|uniprotkb:CBY2(gene name)|psi-mi:CBY2(display_short)|uniprotkb:SPERT(gene name synonym)|uniprotkb:Spermatid-associated protein(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11525207|imex:IM-24995-302	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000001502|refseq:NP_012906.3|go:"GO:0004662"(CAAX-protein geranylgeranyltransferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005953"(CAAX-protein geranylgeranyltransferase complex)|go:"GO:0005965"(protein farnesyltransferase complex)|go:"GO:0007323"(peptide pheromone maturation)|go:"GO:0018343"(protein farnesylation)|go:"GO:0018344"(protein geranylgeranylation)|interpro:IPR002088(Protein prenyltransferase, alpha subunit)|reactome:R-SCE-9648002|ensemblfungi:YKL019W(gene)|ensemblfungi:YKL019W_mRNA(transcript)|go:"GO:0004660"(protein farnesyltransferase activity)|go:"GO:0004661"(protein geranylgeranyltransferase activity)|dip:DIP-1233N|mint:P29703|sgd:YKL019W(identity)	intact:EBI-741724(isoform-parent)|ensembl:ENSG00000174015(gene)|ensembl:ENST00000378966(transcript)|ensembl:ENST00000610924(transcript)|uniprotkb:Q8NA61-2(isoform-parent)|entrezgene/locuslink:220082(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:u2rtpSuSW9Zd8LHWmniip7r5Ycs559292	rogid:SogYcXGGMYRYzB9xKC5o0pEtsDs9606	intact-crc:85DEA9A25F53F390|rigid:i4d4cxUdwD81HyA2LjGD4Qevni8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P30665	uniprotkb:Q9BTE3-2	intact:EBI-4326|uniprotkb:D6W429|ensemblfungi:YPR019W	intact:EBI-9384556|ensembl:ENSP00000358073	psi-mi:mcm4_yeast(display_long)|uniprotkb:MCM4(gene name)|psi-mi:MCM4(display_short)|uniprotkb:HCD21(gene name synonym)|uniprotkb:YPR019W(locus name)|uniprotkb:YP9531.13(orf name)|uniprotkb:CDC54(gene name synonym)|uniprotkb:Cell division control protein 54(gene name synonym)	psi-mi:q9bte3-2(display_long)|uniprotkb:MCMBP(gene name)|psi-mi:MCMBP(display_short)|uniprotkb:C10orf119(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11525216|imex:IM-24995-303	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-2409N|refseq:NP_015344.1|sgd:S000006223|mint:P30665|ensemblfungi:YPR019W(gene)|ensemblfungi:YPR019W_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0033260"(nuclear DNA replication)|go:"GO:0034214"(protein hexamerization)|go:"GO:0042555"(MCM complex)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0071162"(CMG complex)|go:"GO:0097373"(MCM core complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902975"(mitotic DNA replication initiation)|interpro:IPR001208(MCM)|interpro:IPR008047(MCM protein 4)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR036388|interpro:IPR041562|rcsb pdb:3JA8|rcsb pdb:3JC5|rcsb pdb:3JC6|rcsb pdb:3JC7|rcsb pdb:5BK4|rcsb pdb:5U8S|rcsb pdb:5U8T|rcsb pdb:5V8F|rcsb pdb:5XF8|rcsb pdb:6EYC|rcsb pdb:6F0L|rcsb pdb:6HV9|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6RQC|rcsb pdb:6SKL|rcsb pdb:6SKO|rcsb pdb:6U0M|rcsb pdb:6WGF|rcsb pdb:6WGG|rcsb pdb:6WGI|reactome:R-SCE-68949|reactome:R-SCE-68962|reactome:R-SCE-69052|sgd:YPR019W(identity)	intact:EBI-749378(isoform-parent)|uniprotkb:Q9BTE3-2(isoform-parent)|ensembl:ENSG00000197771(gene)|ensembl:ENST00000369077(transcript)|entrezgene/locuslink:79892(identity)	-	crc64:382D542AE38975E3	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:KpsdSZBisjpmXnNAJTZncPINxYI559292	rogid:nJOq6jis1maK+M/X0TcR44HlxRw9606	intact-crc:73CC6C6376DA1235|rigid:YECPGzZy7IokEtBFfv3t22SmfDw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q08379	uniprotkb:P32335	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	intact:EBI-11318|uniprotkb:D6VYK4|ensemblfungi:YLR203C	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:mss51_yeast(display_long)|uniprotkb:MSS51(gene name)|psi-mi:MSS51(display_short)|uniprotkb:YLR203C(locus name)|uniprotkb:L8167.17(orf name)|uniprotkb:Mitochondrial splicing suppressor protein 51(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11525273|imex:IM-24995-309	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N|entrezgene/locuslink:2801(identity)	ensemblfungi:YLR203C(gene)|ensemblfungi:YLR203C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0031314"(extrinsic component of mitochondrial inner membrane)|go:"GO:0033617"(mitochondrial cytochrome c oxidase assembly)|go:"GO:0045182"(translation regulator activity)|go:"GO:0070131"(positive regulation of mitochondrial translation)|interpro:IPR032717|interpro:IPR013272(YL1 nuclear, C-terminal)|sgd:S000004193|refseq:NP_013304.1|mint:P32335|dip:DIP-4602N|sgd:YLR203C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2017/05/26	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	rogid:ytfyoVVQ1W2FaXmytaIbaxZyYjE559292	intact-crc:30BA94C5329567A4|rigid:cV+qhCKhh9qPlAq6QOMTwpceMzI	false	sufficient binding region:383-1002	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P31384	uniprotkb:Q9UFF9	intact:EBI-4396|uniprotkb:D6VPJ7|ensemblfungi:YAL021C	intact:EBI-742299|uniprotkb:O95709|uniprotkb:Q7Z521|uniprotkb:Q9H6Y1|uniprotkb:D3DQI8|uniprotkb:B2RAR8|intact:EBI-10979182|uniprotkb:B0AZS3|uniprotkb:B7Z8R1|ensembl:ENSP00000285896|ensembl:ENSP00000384747|ensembl:ENSP00000430493	psi-mi:ccr4_yeast(display_long)|uniprotkb:CCR4(gene name)|psi-mi:CCR4(display_short)|uniprotkb:Carbon catabolite repressor protein 4(gene name synonym)|uniprotkb:Cytoplasmic deadenylase(gene name synonym)|uniprotkb:Glucose-repressible alcohol dehydrogenase transcriptional effector(gene name synonym)|uniprotkb:FUN27(orf name)|uniprotkb:YAL021C(locus name)	psi-mi:cnot8_human(display_long)|uniprotkb:CNOT8(gene name)|psi-mi:CNOT8(display_short)|uniprotkb:CALIF(gene name synonym)|uniprotkb:POP2(gene name synonym)|uniprotkb:CCR4-associated factor 8(gene name synonym)|uniprotkb:CAF1-like protein(gene name synonym)|uniprotkb:CAF2(gene name synonym)|uniprotkb:Caf1b(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11525246|imex:IM-24995-306	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009381.1|sgd:S000000019|dip:DIP-2522N|mint:P31384|ensemblfungi:YAL021C(gene)|ensemblfungi:YAL021C_mRNA(transcript)|go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0004535"("poly(A)-specific ribonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0007089"(traversing start control point of mitotic cell cycle)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0046872"(metal ion binding)|go:"GO:0048478"(replication fork protection)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR005135(Endonuclease/exonuclease/phosphatase)|interpro:IPR025875|interpro:IPR032675|interpro:IPR036691|rcsb pdb:4B8C|sgd:YAL021C(identity)	refseq:NP_004770.4|refseq:XP_005268584.1|refseq:NP_001288002.1|refseq:NP_001288003.1|refseq:NP_001288004.1|refseq:NP_001288006.1|refseq:NP_001288009.1|refseq:NP_001288011.1|refseq:NP_001288012.1|refseq:NP_001288015.1|refseq:XP_011536008.1|refseq:XP_011536010.1|refseq:XP_016865537.1|refseq:XP_016865538.1|refseq:XP_016865539.1|refseq:XP_016865540.1|refseq:XP_016865541.1|refseq:XP_016865542.1|refseq:XP_016865543.1|refseq:XP_016865544.1|refseq:XP_016865545.1|refseq:XP_016865546.1|ensembl:ENSG00000155508(gene)|ensembl:ENST00000285896(transcript)|ensembl:ENST00000403027(transcript)|ensembl:ENST00000517876(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0004535"("poly(A)-specific ribonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0035195"(gene silencing by miRNA)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0046872"(metal ion binding)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|interpro:IPR006941(Ribonuclease CAF1)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR027212|interpro:IPR036397|interpro:IPR039637|mint:Q9UFF9|reactome:R-HSA-429947|reactome:R-HSA-6804115|dip:DIP-29084N|entrezgene/locuslink:9337(identity)	-	crc64:5CDB2E8FEDDBEF6F	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:f5gxp32WdxKuHQnE8O9/EhhA3Gw559292	rogid:pjaQYzYBGJWC7z5R5s8Te+v2sRA9606	intact-crc:893C4B63A23039F2|rigid:gFrxQ5V6bJZQ9MZJK/RYIsyvq/U	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96CN9	uniprotkb:P31412	intact:EBI-746252|uniprotkb:Q9H6N7|ensembl:ENSP00000318821	intact:EBI-20260|uniprotkb:D6VXK7|ensemblfungi:YKL080W	psi-mi:gcc1_human(display_long)|uniprotkb:Golgi coiled-coil protein 1(gene name synonym)|uniprotkb:GCC1(gene name)|psi-mi:GCC1(display_short)	psi-mi:vatc_yeast(display_long)|uniprotkb:VMA5(gene name)|psi-mi:VMA5(display_short)|uniprotkb:VAT3(gene name synonym)|uniprotkb:VATC(gene name synonym)|uniprotkb:YKL410(orf name)|uniprotkb:YKL080W(locus name)|uniprotkb:Vacuolar proton pump subunit C(gene name synonym)|uniprotkb:V-ATPase 42 kDa subunit(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11525255|imex:IM-24995-307	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_078799.2|ensembl:ENSG00000179562(gene)|ensembl:ENST00000321407(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0031267"(small GTPase binding)|interpro:IPR000237(GRIP)|reactome:R-HSA-6811440|go:"GO:0000138"(Golgi trans cisterna)|entrezgene/locuslink:79571(identity)	refseq:NP_012843.1|sgd:S000001563|ensemblfungi:YKL080W(gene)|ensemblfungi:YKL080W_mRNA(transcript)|go:"GO:0000221"(vacuolar proton-transporting V-type ATPase, V1 domain)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005524"(ATP binding)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|interpro:IPR004907(ATPase, V1 complex, subunit C)|interpro:IPR036132|rcsb pdb:1U7L|rcsb pdb:3J9T|rcsb pdb:3J9U|rcsb pdb:3J9V|rcsb pdb:4DL0|rcsb pdb:4EFA|rcsb pdb:5VOX|rcsb pdb:5VOY|rcsb pdb:5VOZ|rcsb pdb:6O7V|rcsb pdb:6O7W|rcsb pdb:6O7X|reactome:R-SCE-1222556|reactome:R-SCE-77387|reactome:R-SCE-917977|reactome:R-SCE-9639288|dip:DIP-4701N|mint:P31412|sgd:YKL080W(identity)	-	-	crc64:0CD1B814046C377E	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:SCI+peKjPIvl/HbUUpHGM++qiRE9606	rogid:NBI0upCB5yxAyMQgccBcLhjZk8s559292	intact-crc:DD8A3DA4234AAD34|rigid:RtDrn9y+os/mkYe0mRZfc8/yjS8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32335	uniprotkb:A0A0C4DGF1	intact:EBI-11318|uniprotkb:D6VYK4|ensemblfungi:YLR203C	intact:EBI-10188476|ensembl:ENSP00000433657	psi-mi:mss51_yeast(display_long)|uniprotkb:MSS51(gene name)|psi-mi:MSS51(display_short)|uniprotkb:YLR203C(locus name)|uniprotkb:L8167.17(orf name)|uniprotkb:Mitochondrial splicing suppressor protein 51(gene name synonym)	psi-mi:a0a0c4dgf1_human(display_long)|uniprotkb:ZBTB32(gene name)|psi-mi:ZBTB32(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11525264|imex:IM-24995-308	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YLR203C(gene)|ensemblfungi:YLR203C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0031314"(extrinsic component of mitochondrial inner membrane)|go:"GO:0033617"(mitochondrial cytochrome c oxidase assembly)|go:"GO:0045182"(translation regulator activity)|go:"GO:0070131"(positive regulation of mitochondrial translation)|interpro:IPR032717|interpro:IPR013272(YL1 nuclear, C-terminal)|sgd:S000004193|refseq:NP_013304.1|mint:P32335|dip:DIP-4602N|sgd:YLR203C(identity)	interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|ensembl:ENSG00000011590(gene)|ensembl:ENST00000481182(transcript)|go:"GO:0042802"(identical protein binding)|entrezgene/locuslink:27033(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:ytfyoVVQ1W2FaXmytaIbaxZyYjE559292	rogid:w3k7YT4kw/T+Xi5YBqGHSpHtwMM9606	intact-crc:46B1D7F6624AF0C9|rigid:9Z3qT3qmv5F1QZq68kZv2HPQHhk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8IZ13	uniprotkb:P32381	intact:EBI-7186123|ensembl:ENSP00000386184|ensembl:ENSP00000428831|uniprotkb:Q9H5S8|uniprotkb:D3DQJ9|intact:MINT-8163956|intact:MINT-8247520|uniprotkb:Q9UH87	intact:EBI-2927|uniprotkb:D6VRW3|ensemblfungi:YDL029W	psi-mi:zbed8_human(display_long)|uniprotkb:ZBED8(gene name)|psi-mi:ZBED8(display_short)|uniprotkb:Buster3(gene name synonym)|uniprotkb:C5orf54(gene name synonym)|uniprotkb:Transposon-derived Buster3 transposase-like protein(gene name synonym)|uniprotkb:Zinc finger BED domain-containing protein 8(gene name synonym)	psi-mi:arp2_yeast(display_long)|uniprotkb:ACT2(gene name synonym)|uniprotkb:YDL029W(locus name)|uniprotkb:D2778(orf name)|uniprotkb:ARP2(gene name)|psi-mi:ARP2(display_short)|uniprotkb:Actin-like protein ARP2(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11525313|imex:IM-24995-313	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001290180.1|ensembl:ENSG00000221886(gene)|ensembl:ENST00000408953(transcript)|ensembl:ENST00000523213(transcript)|go:"GO:0005654"(nucleoplasm)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR025398|mint:Q8IZ13|refseq:NP_071373.2|entrezgene/locuslink:63920(identity)	refseq:NP_010255.1|sgd:S000002187|dip:DIP-2217N|mint:P32381|ensemblfungi:YDL029W(gene)|ensemblfungi:YDL029W_mRNA(transcript)|go:"GO:0000001"(mitochondrion inheritance)|go:"GO:0003779"(actin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0030476"(ascospore wall assembly)|go:"GO:0030479"(actin cortical patch)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0044396"(actin cortical patch organization)|go:"GO:0051654"(establishment of mitochondrion localization)|interpro:IPR004000(Actin/actin-like)|interpro:IPR020902|interpro:IPR043129|reactome:R-SCE-2029482|reactome:R-SCE-5663213|reactome:R-SCE-6798695|reactome:R-SCE-8856828|sgd:YDL029W(identity)	-	comment:mint	crc64:4C9E8952B477A1B9	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:UMQXSqCyTL0MlOJybHaWQazjfPg9606	rogid:baSDcw/PZH3Z8YHhIcYqtlNO3mw559292	intact-crc:11DBDB57B51928C0|rigid:6GEbCj29ogHagPn37NpLBoQxNaw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32342	uniprotkb:Q9H190	intact:EBI-17984|uniprotkb:D6VXG8|ensemblfungi:YKL122C	intact:EBI-742426|ensembl:ENSP00000371233|uniprotkb:O95892|uniprotkb:Q5W0X1|uniprotkb:Q9BZ42|uniprotkb:Q9H567|uniprotkb:Q9NRY8|intact:EBI-28983470|ensembl:ENSP00000342935|ensembl:ENSP00000354013	psi-mi:srp21_yeast(display_long)|uniprotkb:SRP21(gene name)|psi-mi:SRP21(display_short)|uniprotkb:YKL122C(locus name)|uniprotkb:YKL527(orf name)|uniprotkb:Signal recognition particle 21 kDa protein(gene name synonym)	psi-mi:sdcb2_human(display_long)|uniprotkb:Similar to TACIP18(gene name synonym)|uniprotkb:SDCBP2(gene name)|psi-mi:SDCBP2(display_short)|uniprotkb:SITAC18(gene name synonym)|uniprotkb:Syndecan-binding protein 2(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11525284|imex:IM-24995-310	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012800.1|sgd:S000001605|ensemblfungi:YKL122C(gene)|ensemblfungi:YKL122C_mRNA(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005786"(signal recognition particle, endoplasmic reticulum targeting)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|interpro:IPR039432|reactome:R-SCE-1799339|dip:DIP-4863N|mint:P32342|sgd:YKL122C(identity)	refseq:NP_001186713.1|refseq:NP_056500.2|refseq:NP_536737.3|ensembl:ENSP00000342935|ensembl:ENSP00000354013|ensembl:ENST00000381808|ensembl:ENSP00000371229|ensembl:ENSP00000371233|ensembl:ENSG00000125775(gene)|ensembl:ENST00000360779(transcript)|ensembl:ENST00000381812(transcript)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007399"(nervous system development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016607"(nuclear speck)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046907"(intracellular transport)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036034|interpro:IPR041489|ensembl:ENST00000339987(transcript)|entrezgene/locuslink:27111(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:UXyZkJvr4xO44RgYpDeA8lsND/k559292	rogid:vlEtVZkwLTte5PJ4i8ce+SwE/4Y9606	intact-crc:86C5D20F844256C9|rigid:aHpe/9H37iI703H7ZyZKFbRzWX8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q08379	uniprotkb:P32354	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	intact:EBI-5965|uniprotkb:D6VVD7|ensemblfungi:YIL150C	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:mcm10_yeast(display_long)|uniprotkb:YIL150C(locus name)|uniprotkb:MCM10(gene name)|psi-mi:MCM10(display_short)|uniprotkb:DNA43(gene name synonym)|uniprotkb:Protein DNA43(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11525293|imex:IM-24995-311	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N|entrezgene/locuslink:2801(identity)	refseq:NP_012116.1|sgd:S000001412|dip:DIP-1293N|mint:P32354|ensemblfungi:YIL150C(gene)|ensemblfungi:YIL150C_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005657"(replication fork)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006348"|go:"GO:0007049"(cell cycle)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0046872"(metal ion binding)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR015408(Zinc finger, Mcm10/DnaG-type)|interpro:IPR040184|reactome:R-SCE-68962|sgd:YIL150C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2017/05/26	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	rogid:D2K/tLON/CnIcTTqkAQOdTZrRlg559292	intact-crc:82102370F03A5D31|rigid:+7ogc9529UUncV4bIF3BqIxIVco	false	sufficient binding region:383-1002	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P51116	uniprotkb:P32354	intact:EBI-740459|uniprotkb:Q8WUM2|uniprotkb:Q86V09|uniprotkb:B2R9M2|uniprotkb:D3DTQ1|ensembl:ENSP00000250113	intact:EBI-5965|uniprotkb:D6VVD7|ensemblfungi:YIL150C	psi-mi:fxr2_human(display_long)|uniprotkb:FXR2(gene name)|psi-mi:FXR2(display_short)|uniprotkb:FMR1L2(gene name synonym)	psi-mi:mcm10_yeast(display_long)|uniprotkb:YIL150C(locus name)|uniprotkb:MCM10(gene name)|psi-mi:MCM10(display_short)|uniprotkb:DNA43(gene name synonym)|uniprotkb:Protein DNA43(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11525304|imex:IM-24995-312	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR004087(K Homology)|refseq:NP_004851.2|ensembl:ENSG00000129245(gene)|ensembl:ENST00000250113(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0044326"(dendritic spine neck)|go:"GO:0045182"(translation regulator activity)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0098793"(presynapse)|go:"GO:1902737"(dendritic filopodium)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|interpro:IPR004088(K Homology, type 1)|interpro:IPR008395(Agenet)|interpro:IPR022034|interpro:IPR032172|interpro:IPR036612|interpro:IPR040148|interpro:IPR040472|interpro:IPR041560|mint:P51116|rcsb pdb:3H8Z|entrezgene/locuslink:9513(identity)	refseq:NP_012116.1|sgd:S000001412|dip:DIP-1293N|mint:P32354|ensemblfungi:YIL150C(gene)|ensemblfungi:YIL150C_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005657"(replication fork)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006348"|go:"GO:0007049"(cell cycle)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0046872"(metal ion binding)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR015408(Zinc finger, Mcm10/DnaG-type)|interpro:IPR040184|reactome:R-SCE-68962|sgd:YIL150C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:NnYgyzD2NRGIO1ZHukr5qy44qRE9606	rogid:D2K/tLON/CnIcTTqkAQOdTZrRlg559292	intact-crc:1E26932D5688A873|rigid:+bhE3w6I1kpJayBmaB4tg0UDEQ0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q969L2	uniprotkb:P32453	intact:EBI-944295|uniprotkb:Q6ZMD9|uniprotkb:B2R520|ensembl:ENSP00000479708	intact:EBI-3306|uniprotkb:D6W0N0|ensemblfungi:YNL315C	psi-mi:mal2_human(display_long)|uniprotkb:MAL2(gene name)|psi-mi:MAL2(display_short)	psi-mi:atp11_yeast(display_long)|uniprotkb:ATP11(gene name)|psi-mi:ATP11(display_short)|uniprotkb:N0357(orf name)|uniprotkb:YNL315C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11525358|imex:IM-24995-318	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_443118.1|ensembl:ENSG00000147676(gene)|ensembl:ENST00000614891(transcript)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019911"(structural constituent of myelin sheath)|go:"GO:0042552"(myelination)|go:"GO:0045056"(transcytosis)|go:"GO:0045121"(membrane raft)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|interpro:IPR008253(Marvel)|interpro:IPR013295("Myelin and lymphocyte (MAL)")|interpro:IPR033240|entrezgene/locuslink:114569(identity)	refseq:NP_014084.1|sgd:S000005259|dip:DIP-3026N|mint:P32453|ensemblfungi:YNL315C(gene)|ensemblfungi:YNL315C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0033615"(mitochondrial proton-transporting ATP synthase complex assembly)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR010591(ATP11)|sgd:YNL315C(identity)	-	-	crc64:61109AA4D338F2CD	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:7SApzrGTzj8V3GIwkdO0X/z6geg9606	rogid:JsQu6HtKtGqAVhHzaPVc8IMYdqM559292	intact-crc:A7FF24E71A59EC27|rigid:QrHmWBKsB/Y8StsD9Jm3zScI0eY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8N6L0	uniprotkb:P32453	intact:EBI-749265|uniprotkb:Q96MC3|ensembl:ENSP00000404220	intact:EBI-3306|uniprotkb:D6W0N0|ensemblfungi:YNL315C	psi-mi:kash5_human(display_long)|uniprotkb:KASH5(gene name)|psi-mi:KASH5(display_short)|uniprotkb:CCDC155(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 155(gene name synonym)|uniprotkb:KASH domain-containing protein 5(gene name synonym)	psi-mi:atp11_yeast(display_long)|uniprotkb:ATP11(gene name)|psi-mi:ATP11(display_short)|uniprotkb:N0357(orf name)|uniprotkb:YNL315C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11525349|imex:IM-24995-317	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_653289.3|ensembl:ENSG00000161609(gene)|ensembl:ENST00000447857(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034397"(telomere localization)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051225"(spindle assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0090172"(microtubule cytoskeleton organization involved in homologous chromosome segregation)|go:"GO:0090220"(chromosome localization to nuclear envelope involved in homologous chromosome segregation)|go:"GO:0090619"(meiotic spindle pole)|interpro:IPR011992(EF-Hand type)|interpro:IPR028168|interpro:IPR028170|interpro:IPR039508|mint:Q8N6L0|rcsb pdb:6R2I|rcsb pdb:6WMF|entrezgene/locuslink:147872(identity)	refseq:NP_014084.1|sgd:S000005259|dip:DIP-3026N|mint:P32453|ensemblfungi:YNL315C(gene)|ensemblfungi:YNL315C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0033615"(mitochondrial proton-transporting ATP synthase complex assembly)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR010591(ATP11)|sgd:YNL315C(identity)	-	-	crc64:61109AA4D338F2CD	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Wl9L7AcvDHCZuKjYLn8QgGIbZTc9606	rogid:JsQu6HtKtGqAVhHzaPVc8IMYdqM559292	intact-crc:0D919B78735E26C9|rigid:pDy+f65BuJZxYqNgX8MQxtuukRk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P35520	uniprotkb:P32449	intact:EBI-740135|uniprotkb:Q99425|uniprotkb:Q9BWC5|uniprotkb:B2R993|uniprotkb:D3DSK4|intact:EBI-14245939|ensembl:ENSP00000344460|ensembl:ENSP00000352643|ensembl:ENSP00000381225|ensembl:ENSP00000381231	intact:EBI-2915|uniprotkb:D6VQP5|ensemblfungi:YBR249C	psi-mi:cbs_human(display_long)|uniprotkb:CBS(gene name)|psi-mi:CBS(display_short)|uniprotkb:Serine sulfhydrase(gene name synonym)|uniprotkb:Beta-thionase(gene name synonym)	psi-mi:arog_yeast(display_long)|uniprotkb:ARO4(gene name)|psi-mi:ARO4(display_short)|uniprotkb:YBR249C(locus name)|uniprotkb:YBR1701(orf name)|uniprotkb:Phospho-2-keto-3-deoxyheptonate aldolase(gene name synonym)|uniprotkb:3-deoxy-D-arabino-heptulosonate 7-phosphate synthase(gene name synonym)|uniprotkb:DAHP synthase(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11525322|imex:IM-24995-314	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000062.1|refseq:NP_001171479.1|refseq:NP_001171480.1|ensembl:ENSG00000160200(gene)|ensembl:ENST00000352178(transcript)|ensembl:ENST00000359624(transcript)|ensembl:ENST00000398158(transcript)|go:"GO:0004122"(cystathionine beta-synthase activity)|ensembl:ENST00000398165(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006535"(cysteine biosynthetic process from serine)|go:"GO:0006563"(L-serine metabolic process)|go:"GO:0006565"(L-serine catabolic process)|go:"GO:0019343"(cysteine biosynthetic process via cystathionine)|go:"GO:0019344"(cysteine biosynthetic process)|go:"GO:0019346"(transsulfuration)|go:"GO:0019448"(L-cysteine catabolic process)|go:"GO:0019825"(oxygen binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0020037"(heme binding)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042262"(DNA protection)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043418"(homocysteine catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0050421"("nitrite reductase (NO-forming) activity")|go:"GO:0050667"(homocysteine metabolic process)|go:"GO:0070025"(carbon monoxide binding)|go:"GO:0070026"(nitric oxide binding)|go:"GO:0070814"(hydrogen sulfide biosynthetic process)|go:"GO:0072341"(modified amino acid binding)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR001216(Cysteine synthase/cystathionine beta-synthase P-phosphate-binding site)|interpro:IPR001926(Pyridoxal phosphate-dependent enzyme, beta subunit)|interpro:IPR005857(Cystathionine beta-synthase)|interpro:IPR036052|mint:P35520|rcsb pdb:1JBQ|rcsb pdb:1M54|rcsb pdb:4COO|rcsb pdb:4L0D|rcsb pdb:4L27|rcsb pdb:4L28|rcsb pdb:4L3V|rcsb pdb:4PCU|rcsb pdb:4UUU|rcsb pdb:5MMS|reactome:R-HSA-1614603|reactome:R-HSA-2408508|refseq:XP_011528079.1|refseq:XP_011528083.1|refseq:XP_011528084.1|refseq:XP_011544396.1|refseq:XP_011544397.1|refseq:XP_011544399.1|refseq:XP_011544400.1|refseq:XP_011544401.1|refseq:NP_001307227.1|refseq:NP_001308002.1|refseq:XP_016883700.1|refseq:XP_016883701.1|refseq:XP_016883702.1|refseq:XP_016883703.1|refseq:XP_016883704.1|refseq:XP_016883705.1|refseq:XP_016883706.1|refseq:XP_016883707.1|refseq:XP_016883978.1|refseq:XP_016883979.1|refseq:XP_016883980.1|refseq:XP_016883981.1|entrezgene/locuslink:875(identity)	refseq:NP_009808.1|sgd:S000000453|dip:DIP-4175N|mint:P32449|ensemblfungi:YBR249C(gene)|ensemblfungi:YBR249C_mRNA(transcript)|go:"GO:0003849"(3-deoxy-7-phosphoheptulonate synthase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008652"(cellular amino acid biosynthetic process)|go:"GO:0009073"(aromatic amino acid family biosynthetic process)|go:"GO:0009423"(chorismate biosynthetic process)|interpro:IPR006218(DAHP synthetase I/KDSA)|interpro:IPR006219(DHAP synthase, class 1)|interpro:IPR013785(Aldolase-type TIM barrel)|rcsb pdb:1HFB|rcsb pdb:1OAB|rcsb pdb:1OF6|rcsb pdb:1OF8|rcsb pdb:1OFA|rcsb pdb:1OFB|rcsb pdb:1OFO|rcsb pdb:1OFP|rcsb pdb:1OFQ|rcsb pdb:1OFR|rcsb pdb:1OG0|sgd:YBR249C(identity)	-	-	crc64:594ED48F24175979	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:f9eo0cPOHppVY7Nqejag3YyK18s9606	rogid:y1YXaSHJozc5Q77Q8LqQ61IA6Lw559292	intact-crc:F16F40A1061A37E8|rigid:ZtvOayfnVEJ2d3guFmvfzRJhXps	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32453	uniprotkb:Q15041	intact:EBI-3306|uniprotkb:D6W0N0|ensemblfungi:YNL315C	intact:EBI-714543|ensembl:ENSP00000306788|uniprotkb:B7Z6S5|uniprotkb:B7Z791|uniprotkb:F5GXP4	psi-mi:atp11_yeast(display_long)|uniprotkb:ATP11(gene name)|psi-mi:ATP11(display_short)|uniprotkb:N0357(orf name)|uniprotkb:YNL315C(locus name)	psi-mi:ar6p1_human(display_long)|uniprotkb:ARL6IP(gene name synonym)|uniprotkb:ARL6IP1(gene name)|psi-mi:ARL6IP1(display_short)|uniprotkb:KIAA0069(gene name synonym)|uniprotkb:ARMER(gene name synonym)|uniprotkb:Apoptotic regulator in the membrane of the endoplasmic reticulum(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11525331|imex:IM-24995-315	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014084.1|sgd:S000005259|dip:DIP-3026N|mint:P32453|ensemblfungi:YNL315C(gene)|ensemblfungi:YNL315C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0033615"(mitochondrial proton-transporting ATP synthase complex assembly)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR010591(ATP11)|sgd:YNL315C(identity)	refseq:NP_055976.1|ensembl:ENSG00000170540(gene)|ensembl:ENST00000304414(transcript)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006613"(cotranslational protein targeting to membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0071787"(endoplasmic reticulum tubular network formation)|go:"GO:1903371"(regulation of endoplasmic reticulum tubular network organization)|go:"GO:1990809"(endoplasmic reticulum tubular network membrane organization)|interpro:IPR033301|mint:Q15041|go:"GO:0002038"(positive regulation of L-glutamate import across plasma membrane)|refseq:NP_001300787.1|entrezgene/locuslink:23204(identity)	-	crc64:61109AA4D338F2CD	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:JsQu6HtKtGqAVhHzaPVc8IMYdqM559292	rogid:3fjkoyvUx25po7xsPcXgpjEeLJg9606	intact-crc:1318F9246B39C6F3|rigid:yyzxtYV9KcvFNA2QogAC0WqTvFY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q6RW13-2	uniprotkb:P32453	intact:EBI-11522760|ensembl:ENSP00000365816	intact:EBI-3306|uniprotkb:D6W0N0|ensemblfungi:YNL315C	psi-mi:q6rw13-2(display_long)|uniprotkb:AGTRAP(gene name)|psi-mi:AGTRAP(display_short)|uniprotkb:AT1 receptor-associated protein(gene name synonym)|uniprotkb:ATRAP(gene name synonym)	psi-mi:atp11_yeast(display_long)|uniprotkb:ATP11(gene name)|psi-mi:ATP11(display_short)|uniprotkb:N0357(orf name)|uniprotkb:YNL315C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11525340|imex:IM-24995-316	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000177674(gene)|ensembl:ENST00000376629(transcript)|intact:EBI-741181(isoform-parent)|uniprotkb:Q6RW13-2(isoform-parent)|entrezgene/locuslink:57085(identity)	refseq:NP_014084.1|sgd:S000005259|dip:DIP-3026N|mint:P32453|ensemblfungi:YNL315C(gene)|ensemblfungi:YNL315C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0033615"(mitochondrial proton-transporting ATP synthase complex assembly)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR010591(ATP11)|sgd:YNL315C(identity)	-	-	crc64:61109AA4D338F2CD	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:PNzVis/8puQZBJ562gCqZKc078s9606	rogid:JsQu6HtKtGqAVhHzaPVc8IMYdqM559292	intact-crc:18DCFDDA9D5B4322|rigid:Gl/aNuCOn/VnsjWxu27bfTvUiH8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q15019-3	uniprotkb:P32458	intact:EBI-11525407|ensembl:ENSP00000385109	intact:EBI-4178|uniprotkb:D6VWP6|ensemblfungi:YJR076C	psi-mi:q15019-3(display_long)|uniprotkb:SEPTIN2(gene name)|psi-mi:SEPTIN2(display_short)|uniprotkb:DIFF6(gene name synonym)|uniprotkb:KIAA0158(gene name synonym)|uniprotkb:NEDD5(gene name synonym)|uniprotkb:Neural precursor cell expressed developmentally down-regulated protein 5(gene name synonym)|uniprotkb:SEPT2(gene name synonym)	psi-mi:cdc11_yeast(display_long)|uniprotkb:CDC11(gene name)|psi-mi:CDC11(display_short)|uniprotkb:PSL9(gene name synonym)|uniprotkb:YJR076C(locus name)|uniprotkb:J1833(orf name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11525411|imex:IM-24995-323	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000401990(transcript)|ensembl:ENSG00000168385(gene)|intact:EBI-741220(isoform-parent)|uniprotkb:Q15019-3(isoform-parent)|entrezgene/locuslink:4735(identity)	refseq:NP_012610.1|sgd:S000003837|dip:DIP-1656N|mint:P32458|ensemblfungi:YJR076C(gene)|ensemblfungi:YJR076C_mRNA(transcript)|go:"GO:0000144"(cellular bud neck septin ring)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000915"(actomyosin contractile ring assembly)|go:"GO:0000917"(division septum assembly)|go:"GO:0001400"(mating projection base)|go:"GO:0003924"(GTPase activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005619"(ascospore wall)|go:"GO:0005628"(prospore membrane)|go:"GO:0005876"(spindle microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0005935"(cellular bud neck)|go:"GO:0005940"(septin ring)|go:"GO:0010314"(phosphatidylinositol-5-phosphate binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030011"(maintenance of cell polarity)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0032160"(septin filament array)|go:"GO:0032186"(cellular bud neck septin ring organization)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042802"(identical protein binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0072687"(meiotic spindle)|go:"GO:0097271"(protein localization to bud neck)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|rcsb pdb:5AR1|sgd:YJR076C(identity)	-	isoform-comment:No experimental confirmation available.	crc64:5CFFD4CD1F6C57D4	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:fBY0oYn+bn7aJbJr9OyZEpqkhLc9606	rogid:KRcNMx6EOTmvHb+6u15UrVoyb3s559292	intact-crc:D17AC5E2439F6C68|rigid:QIyrwTQRextVuKXuXcgYW43FQbQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32458	uniprotkb:P63279	intact:EBI-4178|uniprotkb:D6VWP6|ensemblfungi:YJR076C	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	psi-mi:cdc11_yeast(display_long)|uniprotkb:CDC11(gene name)|psi-mi:CDC11(display_short)|uniprotkb:PSL9(gene name synonym)|uniprotkb:YJR076C(locus name)|uniprotkb:J1833(orf name)	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11525398|imex:IM-24995-322	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012610.1|sgd:S000003837|dip:DIP-1656N|mint:P32458|ensemblfungi:YJR076C(gene)|ensemblfungi:YJR076C_mRNA(transcript)|go:"GO:0000144"(cellular bud neck septin ring)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000915"(actomyosin contractile ring assembly)|go:"GO:0000917"(division septum assembly)|go:"GO:0001400"(mating projection base)|go:"GO:0003924"(GTPase activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005619"(ascospore wall)|go:"GO:0005628"(prospore membrane)|go:"GO:0005876"(spindle microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0005935"(cellular bud neck)|go:"GO:0005940"(septin ring)|go:"GO:0010314"(phosphatidylinositol-5-phosphate binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030011"(maintenance of cell polarity)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0032160"(septin filament array)|go:"GO:0032186"(cellular bud neck septin ring organization)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042802"(identical protein binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0072687"(meiotic spindle)|go:"GO:0097271"(protein localization to bud neck)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|rcsb pdb:5AR1|sgd:YJR076C(identity)	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N|entrezgene/locuslink:7329(identity)	-	crc64:5CFFD4CD1F6C57D4	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:KRcNMx6EOTmvHb+6u15UrVoyb3s559292	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	intact-crc:DEFB9C16C242BBDF|rigid:1L1ArCGXPA6CF4VZPo9nfrMSdDM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32453	uniprotkb:Q96DZ9-2	intact:EBI-3306|uniprotkb:D6W0N0|ensemblfungi:YNL315C	intact:EBI-11522780|ensembl:ENSP00000352270|ensembl:ENSP00000497215	psi-mi:atp11_yeast(display_long)|uniprotkb:ATP11(gene name)|psi-mi:ATP11(display_short)|uniprotkb:N0357(orf name)|uniprotkb:YNL315C(locus name)	psi-mi:q96dz9-2(display_long)|uniprotkb:CMTM5(gene name)|psi-mi:CMTM5(display_short)|uniprotkb:CKLFSF5(gene name synonym)|uniprotkb:Chemokine-like factor superfamily member 5(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11525367|imex:IM-24995-319	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014084.1|sgd:S000005259|dip:DIP-3026N|mint:P32453|ensemblfungi:YNL315C(gene)|ensemblfungi:YNL315C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0033615"(mitochondrial proton-transporting ATP synthase complex assembly)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR010591(ATP11)|sgd:YNL315C(identity)	ensembl:ENSG00000166091(gene)|ensembl:ENST00000359320(transcript)|ensembl:ENST00000649278(transcript)|intact:EBI-2548702(isoform-parent)|uniprotkb:Q96DZ9-2(isoform-parent)|entrezgene/locuslink:116173(identity)	-	crc64:61109AA4D338F2CD	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:JsQu6HtKtGqAVhHzaPVc8IMYdqM559292	rogid:2TJ7rZKQNb5hH5gz9i+ujOEOIOg9606	intact-crc:E0972F9C85B5EBA2|rigid:bdERYZdEf3ixhCdnf5xhi5ZNSm0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32458	uniprotkb:B0QYN7	intact:EBI-4178|uniprotkb:D6VWP6|ensemblfungi:YJR076C	intact:EBI-11525376|ensembl:ENSP00000384361	psi-mi:cdc11_yeast(display_long)|uniprotkb:CDC11(gene name)|psi-mi:CDC11(display_short)|uniprotkb:PSL9(gene name synonym)|uniprotkb:YJR076C(locus name)|uniprotkb:J1833(orf name)	psi-mi:b0qyn7_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11525380|imex:IM-24995-320	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012610.1|sgd:S000003837|dip:DIP-1656N|mint:P32458|ensemblfungi:YJR076C(gene)|ensemblfungi:YJR076C_mRNA(transcript)|go:"GO:0000144"(cellular bud neck septin ring)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000915"(actomyosin contractile ring assembly)|go:"GO:0000917"(division septum assembly)|go:"GO:0001400"(mating projection base)|go:"GO:0003924"(GTPase activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005619"(ascospore wall)|go:"GO:0005628"(prospore membrane)|go:"GO:0005876"(spindle microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0005935"(cellular bud neck)|go:"GO:0005940"(septin ring)|go:"GO:0010314"(phosphatidylinositol-5-phosphate binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030011"(maintenance of cell polarity)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0032160"(septin filament array)|go:"GO:0032186"(cellular bud neck septin ring organization)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042802"(identical protein binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0072687"(meiotic spindle)|go:"GO:0097271"(protein localization to bud neck)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|rcsb pdb:5AR1|sgd:YJR076C(identity)	refseq:XP_005255597.1|refseq:XP_005255598.1|refseq:XP_011520946.1|refseq:XP_011520947.1|ensembl:ENSG00000103275(gene)|ensembl:ENST00000402301(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0016740"(transferase activity)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|entrezgene/locuslink:7329(identity)	-	crc64:5CFFD4CD1F6C57D4	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:KRcNMx6EOTmvHb+6u15UrVoyb3s559292	rogid:zMqQOA+nnCUquTIxAUwemkElTYI9606	intact-crc:0DFD781820D73570|rigid:fb7aFDxlDpe3aiScIPewKqW1zHU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32458	uniprotkb:P23497-2	intact:EBI-4178|uniprotkb:D6VWP6|ensemblfungi:YJR076C	intact:EBI-6589365|ensembl:ENSP00000386404	psi-mi:cdc11_yeast(display_long)|uniprotkb:CDC11(gene name)|psi-mi:CDC11(display_short)|uniprotkb:PSL9(gene name synonym)|uniprotkb:YJR076C(locus name)|uniprotkb:J1833(orf name)	psi-mi:p23497-2(display_long)|uniprotkb:SP100(isoform synonym)|uniprotkb:SP100(gene name)|psi-mi:SP100(display_short)|uniprotkb:Nuclear dot-associated Sp100 protein(gene name synonym)|uniprotkb:Speckled 100 kDa(gene name synonym)|uniprotkb:SP100A(isoform synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11525389|imex:IM-24995-321	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012610.1|sgd:S000003837|dip:DIP-1656N|mint:P32458|ensemblfungi:YJR076C(gene)|ensemblfungi:YJR076C_mRNA(transcript)|go:"GO:0000144"(cellular bud neck septin ring)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000915"(actomyosin contractile ring assembly)|go:"GO:0000917"(division septum assembly)|go:"GO:0001400"(mating projection base)|go:"GO:0003924"(GTPase activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005619"(ascospore wall)|go:"GO:0005628"(prospore membrane)|go:"GO:0005876"(spindle microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0005935"(cellular bud neck)|go:"GO:0005940"(septin ring)|go:"GO:0010314"(phosphatidylinositol-5-phosphate binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030011"(maintenance of cell polarity)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0032160"(septin filament array)|go:"GO:0032186"(cellular bud neck septin ring organization)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042802"(identical protein binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0072687"(meiotic spindle)|go:"GO:0097271"(protein localization to bud neck)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|rcsb pdb:5AR1|sgd:YJR076C(identity)	intact:EBI-751145(isoform-parent)|uniprotkb:P23497-2(isoform-parent)|ensembl:ENSG00000067066(gene)|ensembl:ENST00000409341(transcript)|entrezgene/locuslink:6672(identity)	-	crc64:5CFFD4CD1F6C57D4	isoform-comment:Major isoform.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:KRcNMx6EOTmvHb+6u15UrVoyb3s559292	rogid:HrcogLANB///4vkSYtZ7OtzOb2k9606	intact-crc:C2558838CDF386F7|rigid:VtSDFukPmOGOWGX4zAcA3fIbVI4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32463	uniprotkb:O43281-2	intact:EBI-2113|uniprotkb:D6VX08|ensemblfungi:YKL192C	intact:EBI-11525448|ensembl:ENSP00000340607	psi-mi:acpm_yeast(display_long)|uniprotkb:ACP1(gene name)|psi-mi:ACP1(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 9.6 kDa subunit(gene name synonym)|uniprotkb:YKL192C(locus name)	psi-mi:o43281-2(display_long)|uniprotkb:CASS3(gene name synonym)|uniprotkb:Cas scaffolding protein family member 3(gene name synonym)|uniprotkb:EFS(gene name)|psi-mi:EFS(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11525446|imex:IM-24995-326	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012729.1|sgd:S000001675|dip:DIP-3990N|mint:P32463|ensemblfungi:YKL192C(gene)|ensemblfungi:YKL192C_mRNA(transcript)|go:"GO:0000035"(acyl binding)|go:"GO:0000036"(acyl carrier activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0009107"(lipoate biosynthetic process)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0070469"(respirasome)|go:"GO:0099128"(mitochondrial iron-sulfur cluster assembly complex)|interpro:IPR003231("Acyl carrier protein (ACP)")|interpro:IPR006162(Phosphopantetheine attachment site)|interpro:IPR009081(Acyl carrier protein-like)|interpro:IPR036736|reactome:R-SCE-389661|reactome:R-SCE-77289|sgd:YKL192C(identity)	intact:EBI-718488(isoform-parent)|ensembl:ENSG00000100842(gene)|ensembl:ENST00000351354(transcript)|uniprotkb:O43281-2(isoform-parent)|entrezgene/locuslink:10278(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:u1Dnj7iL+Ty5d20JWalQsAUxAS4559292	rogid:JdV6uL2+FglKvl/B+OVXk/eIIKQ9606	intact-crc:34A18929C91AAEDB|rigid:FWmc9lAegRJYcR77EXv33eoE0jk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9Y2J4	uniprotkb:P32458	intact:EBI-746752|intact:EBI-28986657|ensembl:ENSP00000409999|uniprotkb:Q53EP1|uniprotkb:Q96F99|uniprotkb:Q9UKB4|uniprotkb:A8K6F1|uniprotkb:B7Z5Q1|uniprotkb:E9PHW3	intact:EBI-4178|uniprotkb:D6VWP6|ensemblfungi:YJR076C	psi-mi:amol2_human(display_long)|uniprotkb:Leman coiled-coil protein(gene name synonym)|uniprotkb:AMOTL2(gene name)|psi-mi:AMOTL2(display_short)|uniprotkb:KIAA0989(gene name synonym)	psi-mi:cdc11_yeast(display_long)|uniprotkb:CDC11(gene name)|psi-mi:CDC11(display_short)|uniprotkb:PSL9(gene name synonym)|uniprotkb:YJR076C(locus name)|uniprotkb:J1833(orf name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11525420|imex:IM-24995-324	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001265612.1|refseq:NP_001265614.1|ensembl:ENSG00000114019(gene)|refseq:XP_006713717.1|refseq:NP_057285.3|refseq:XP_011511183.1|ensembl:ENST00000422605(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0003365"(establishment of cell polarity involved in ameboidal cell migration)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0035329"(hippo signaling)|go:"GO:0055037"(recycling endosome)|interpro:IPR009114(Angiomotin)|interpro:IPR024646|mint:Q9Y2J4|reactome:R-HSA-2028269|refseq:XP_016862069.1|refseq:XP_016862070.1|refseq:XP_016862071.1|ensembl:ENST00000249883|ensembl:ENSP00000249883|ensembl:ENSP00000409999|ensembl:ENST00000513145|ensembl:ENSP00000425475|ensembl:ENST00000514516|ensembl:ENSP00000424765|dip:DIP-57510N|entrezgene/locuslink:51421(identity)	refseq:NP_012610.1|sgd:S000003837|dip:DIP-1656N|mint:P32458|ensemblfungi:YJR076C(gene)|ensemblfungi:YJR076C_mRNA(transcript)|go:"GO:0000144"(cellular bud neck septin ring)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000915"(actomyosin contractile ring assembly)|go:"GO:0000917"(division septum assembly)|go:"GO:0001400"(mating projection base)|go:"GO:0003924"(GTPase activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005619"(ascospore wall)|go:"GO:0005628"(prospore membrane)|go:"GO:0005876"(spindle microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0005935"(cellular bud neck)|go:"GO:0005940"(septin ring)|go:"GO:0010314"(phosphatidylinositol-5-phosphate binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030011"(maintenance of cell polarity)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0032160"(septin filament array)|go:"GO:0032186"(cellular bud neck septin ring organization)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042802"(identical protein binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0072687"(meiotic spindle)|go:"GO:0097271"(protein localization to bud neck)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|rcsb pdb:5AR1|sgd:YJR076C(identity)	-	-	crc64:5CFFD4CD1F6C57D4	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:SHtKAcLLnTpSSLwVE7yQ1WECoZk9606	rogid:KRcNMx6EOTmvHb+6u15UrVoyb3s559292	intact-crc:913EBF11BC816785|rigid:jvPfSTR3KoFtSOGZW0zusIT43Pw	false	sufficient binding region:314-779	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:H0YCX2	uniprotkb:P32463	intact:EBI-11525431|ensembl:ENSP00000432463	intact:EBI-2113|uniprotkb:D6VX08|ensemblfungi:YKL192C	psi-mi:h0ycx2_human(display_long)|uniprotkb:FAM193B(gene name)|psi-mi:FAM193B(display_short)	psi-mi:acpm_yeast(display_long)|uniprotkb:ACP1(gene name)|psi-mi:ACP1(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 9.6 kDa subunit(gene name synonym)|uniprotkb:YKL192C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11525435|imex:IM-24995-325	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000146067(gene)|ensembl:ENST00000524677(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0016607"(nuclear speck)|interpro:IPR029717|interpro:IPR029722|interpro:IPR031802|entrezgene/locuslink:54540(identity)	refseq:NP_012729.1|sgd:S000001675|dip:DIP-3990N|mint:P32463|ensemblfungi:YKL192C(gene)|ensemblfungi:YKL192C_mRNA(transcript)|go:"GO:0000035"(acyl binding)|go:"GO:0000036"(acyl carrier activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0009107"(lipoate biosynthetic process)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0070469"(respirasome)|go:"GO:0099128"(mitochondrial iron-sulfur cluster assembly complex)|interpro:IPR003231("Acyl carrier protein (ACP)")|interpro:IPR006162(Phosphopantetheine attachment site)|interpro:IPR009081(Acyl carrier protein-like)|interpro:IPR036736|reactome:R-SCE-389661|reactome:R-SCE-77289|sgd:YKL192C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:aMr6uO1ZOLPg/THCfO6xLJWkO7Y9606	rogid:u1Dnj7iL+Ty5d20JWalQsAUxAS4559292	intact-crc:C8950E5194BD8154|rigid:re4U2XvrEj12Jkyq5nuQJkV7lmM	false	sufficient binding region:61-508	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32464	uniprotkb:Q86WT6-2	intact:EBI-8859|ensemblfungi:YKL189W|uniprotkb:D6VX11	intact:EBI-11525489|ensembl:ENSP00000342922|ensembl:ENSP00000479720	psi-mi:hym1_yeast(display_long)|uniprotkb:YKL189W(locus name)|uniprotkb:HYM1(gene name)|psi-mi:HYM1(display_short)	psi-mi:q86wt6-2(display_long)|uniprotkb:RING-type E3 ubiquitin transferase TRIM69(gene name synonym)|uniprotkb:TRIM69(gene name)|psi-mi:TRIM69(display_short)|uniprotkb:RFP-like domain-containing protein trimless(gene name synonym)|uniprotkb:RING finger protein 36(gene name synonym)|uniprotkb:RNF36(gene name synonym)|uniprotkb:Tripartite motif-containing protein 69(gene name synonym)|uniprotkb:HSD-34(orf name)|uniprotkb:HSD34(orf name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11525493|imex:IM-24995-330	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YKL189W(gene)|ensemblfungi:YKL189W_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0000920"(septum digestion after cytokinesis)|go:"GO:0005933"(cellular bud)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007118"(budding cell apical bud growth)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043332"(mating projection tip)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0044732"(mitotic spindle pole body)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013878(Mo25-like)|interpro:IPR016024(Armadillo-type fold)|reactome:R-SCE-6798695|refseq:NP_012732.1|sgd:S000001672|mint:P32464|dip:DIP-5425N|sgd:YKL189W(identity)	intact:EBI-749955(isoform-parent)|uniprotkb:Q86WT6-2(isoform-parent)|ensembl:ENSG00000185880(gene)|ensembl:ENSG00000278211(gene)|ensembl:ENST00000338264(transcript)|ensembl:ENST00000618398(transcript)|entrezgene/locuslink:140691(identity)	-	crc64:F48860754C892BA9	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:pOlQFFuYgFzmqf3ZGUVkBj9h7Uc559292	rogid:J0mzn4PSX5vWZqt4X3Ee1Wxx5hw9606	intact-crc:30832B8E29759C03|rigid:iy9StxYBZ2cOGdyRWb1zM+gLOQA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32464	uniprotkb:Q08379	intact:EBI-8859|ensemblfungi:YKL189W|uniprotkb:D6VX11	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	psi-mi:hym1_yeast(display_long)|uniprotkb:YKL189W(locus name)|uniprotkb:HYM1(gene name)|psi-mi:HYM1(display_short)	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11525459|imex:IM-24995-327	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YKL189W(gene)|ensemblfungi:YKL189W_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0000920"(septum digestion after cytokinesis)|go:"GO:0005933"(cellular bud)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007118"(budding cell apical bud growth)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043332"(mating projection tip)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0044732"(mitotic spindle pole body)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013878(Mo25-like)|interpro:IPR016024(Armadillo-type fold)|reactome:R-SCE-6798695|refseq:NP_012732.1|sgd:S000001672|mint:P32464|dip:DIP-5425N|sgd:YKL189W(identity)	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N|entrezgene/locuslink:2801(identity)	-	crc64:F48860754C892BA9	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2017/05/26	rogid:pOlQFFuYgFzmqf3ZGUVkBj9h7Uc559292	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	intact-crc:B3FCF5BB777456FE|rigid:TQTCCQDUSkfgGVImrqXaG4EjE+c	false	-	sufficient binding region:383-1002	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O14879	uniprotkb:P32464	intact:EBI-745127|uniprotkb:Q99634|uniprotkb:Q9BSK7|ensembl:ENSP00000360876|ensembl:ENSP00000360883|ensembl:ENSP00000505987	intact:EBI-8859|ensemblfungi:YKL189W|uniprotkb:D6VX11	psi-mi:ifit3_human(display_long)|uniprotkb:ISG-60(gene name synonym)|uniprotkb:CIG49(gene name synonym)|uniprotkb:Retinoic acid-induced gene G protein(gene name synonym)|uniprotkb:Interferon-induced protein with tetratricopeptide repeats 4(gene name synonym)|uniprotkb:Interferon-induced 60 kDa protein(gene name synonym)|uniprotkb:IFIT3(gene name)|psi-mi:IFIT3(display_short)|uniprotkb:IFI60(gene name synonym)|uniprotkb:IFIT4(gene name synonym)|uniprotkb:CIG-49(gene name synonym)|uniprotkb:ISG60(gene name synonym)	psi-mi:hym1_yeast(display_long)|uniprotkb:YKL189W(locus name)|uniprotkb:HYM1(gene name)|psi-mi:HYM1(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11525470|imex:IM-24995-328	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001026853.1|refseq:NP_001540.2|ensembl:ENSG00000119917(gene)|ensembl:ENST00000371811(transcript)|ensembl:ENST00000371818(transcript)|ensembl:ENST00000679781(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009615"(response to virus)|go:"GO:0035457"(cellular response to interferon-alpha)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR024122|mint:O14879|rcsb pdb:6C6K|reactome:R-HSA-909733|dip:DIP-37890N|entrezgene/locuslink:3437(identity)	ensemblfungi:YKL189W(gene)|ensemblfungi:YKL189W_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0000920"(septum digestion after cytokinesis)|go:"GO:0005933"(cellular bud)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007118"(budding cell apical bud growth)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043332"(mating projection tip)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0044732"(mitotic spindle pole body)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013878(Mo25-like)|interpro:IPR016024(Armadillo-type fold)|reactome:R-SCE-6798695|refseq:NP_012732.1|sgd:S000001672|mint:P32464|dip:DIP-5425N|sgd:YKL189W(identity)	-	-	crc64:F48860754C892BA9	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:K8uDHfKNx0YBgTkwpEaRKvx24/k9606	rogid:pOlQFFuYgFzmqf3ZGUVkBj9h7Uc559292	intact-crc:F004C6588D1C8009|rigid:1oLkIlyzqwp89jwljG2iTwKN9ww	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32464	uniprotkb:P14373	intact:EBI-8859|ensemblfungi:YKL189W|uniprotkb:D6VX11	intact:EBI-719493|uniprotkb:A2BE15|uniprotkb:Q5RJA8|uniprotkb:Q5ST26|uniprotkb:Q6LA73|uniprotkb:Q6NXR9|uniprotkb:Q9BZY6|uniprotkb:Q9UJL3|ensembl:ENSP00000383555|ensembl:ENSP00000392787|ensembl:ENSP00000405229|ensembl:ENSP00000414793|ensembl:ENSP00000366404	psi-mi:hym1_yeast(display_long)|uniprotkb:YKL189W(locus name)|uniprotkb:HYM1(gene name)|psi-mi:HYM1(display_short)	psi-mi:tri27_human(display_long)|uniprotkb:TRIM27(gene name)|psi-mi:TRIM27(display_short)|uniprotkb:RNF76(gene name synonym)|uniprotkb:RFP(gene name synonym)|uniprotkb:Ret finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 27(gene name synonym)|uniprotkb:RING finger protein 76(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM27(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11525480|imex:IM-24995-329	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YKL189W(gene)|ensemblfungi:YKL189W_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0000920"(septum digestion after cytokinesis)|go:"GO:0005933"(cellular bud)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007118"(budding cell apical bud growth)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043332"(mating projection tip)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0044732"(mitotic spindle pole body)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013878(Mo25-like)|interpro:IPR016024(Armadillo-type fold)|reactome:R-SCE-6798695|refseq:NP_012732.1|sgd:S000001672|mint:P32464|dip:DIP-5425N|sgd:YKL189W(identity)	refseq:NP_006501.1|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0090281"(negative regulation of calcium ion import)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR020457|interpro:IPR035791|interpro:IPR043136|mint:P14373|reactome:R-HSA-3232142|reactome:R-HSA-9635465|reactome:R-HSA-8948751|ensembl:ENSG00000204713(gene)|ensembl:ENSG00000215641(gene)|ensembl:ENSG00000229006(gene)|ensembl:ENSG00000234495(gene)|ensembl:ENSG00000237071(gene)|ensembl:ENST00000377199(transcript)|ensembl:ENST00000400720(transcript)|ensembl:ENST00000431123(transcript)|ensembl:ENST00000435528(transcript)|ensembl:ENST00000437160(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001650"(fibrillar center)|go:"GO:0002820"(negative regulation of adaptive immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|entrezgene/locuslink:5987(identity)	-	crc64:F48860754C892BA9	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:pOlQFFuYgFzmqf3ZGUVkBj9h7Uc559292	rogid:dsfH5OUghD8KSaTz1SFw9OYVTK49606	intact-crc:A11F4919A30A6318|rigid:2igrLlIUhR+ddAP5LUqSOBOq6IE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32464	uniprotkb:Q9BYV6-2	intact:EBI-8859|ensemblfungi:YKL189W|uniprotkb:D6VX11	intact:EBI-11522718|ensembl:ENSP00000297348	psi-mi:hym1_yeast(display_long)|uniprotkb:YKL189W(locus name)|uniprotkb:HYM1(gene name)|psi-mi:HYM1(display_short)	psi-mi:q9byv6-2(display_long)|uniprotkb:TRIM55(gene name)|psi-mi:TRIM55(display_short)|uniprotkb:MURF2(gene name synonym)|uniprotkb:Muscle-specific RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 29(gene name synonym)|uniprotkb:RNF29(gene name synonym)|uniprotkb:p50(isoform synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11525529|imex:IM-24995-334	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YKL189W(gene)|ensemblfungi:YKL189W_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0000920"(septum digestion after cytokinesis)|go:"GO:0005933"(cellular bud)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007118"(budding cell apical bud growth)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043332"(mating projection tip)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0044732"(mitotic spindle pole body)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013878(Mo25-like)|interpro:IPR016024(Armadillo-type fold)|reactome:R-SCE-6798695|refseq:NP_012732.1|sgd:S000001672|mint:P32464|dip:DIP-5425N|sgd:YKL189W(identity)	intact:EBI-2341179(isoform-parent)|uniprotkb:Q9BYV6-2(isoform-parent)|ensembl:ENSG00000147573(gene)|ensembl:ENST00000353317(transcript)|entrezgene/locuslink:84675(identity)	-	crc64:F48860754C892BA9	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:pOlQFFuYgFzmqf3ZGUVkBj9h7Uc559292	rogid:9t8UhK+Z1yBqjnQrOqPD76NuXGg9606	intact-crc:547133E685711FB0|rigid:Q00+a0cI06mHJvICa9lINScSzyk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8N3J3-3	uniprotkb:P32464	intact:EBI-11061081|ensembl:ENSP00000245382	intact:EBI-8859|ensemblfungi:YKL189W|uniprotkb:D6VX11	psi-mi:q8n3j3-3(display_long)|uniprotkb:HROB(gene name)|psi-mi:HROB(display_short)|uniprotkb:C17orf53(gene name synonym)	psi-mi:hym1_yeast(display_long)|uniprotkb:YKL189W(locus name)|uniprotkb:HYM1(gene name)|psi-mi:HYM1(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11525502|imex:IM-24995-331	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8465499(isoform-parent)|uniprotkb:Q8N3J3-3(isoform-parent)|ensembl:ENSG00000125319(gene)|ensembl:ENST00000245382(transcript)|entrezgene/locuslink:78995(identity)	ensemblfungi:YKL189W(gene)|ensemblfungi:YKL189W_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0000920"(septum digestion after cytokinesis)|go:"GO:0005933"(cellular bud)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007118"(budding cell apical bud growth)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043332"(mating projection tip)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0044732"(mitotic spindle pole body)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013878(Mo25-like)|interpro:IPR016024(Armadillo-type fold)|reactome:R-SCE-6798695|refseq:NP_012732.1|sgd:S000001672|mint:P32464|dip:DIP-5425N|sgd:YKL189W(identity)	-	isoform-comment:No experimental confirmation available.	crc64:F48860754C892BA9	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:CV8rVs1P1HH0w/igNSebho0bupA9606	rogid:pOlQFFuYgFzmqf3ZGUVkBj9h7Uc559292	intact-crc:AAB7519DAD5FBE16|rigid:4axyQ/CKyNEmBlfsCq5Oe22Q6PE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32464	uniprotkb:Q8NA61-2	intact:EBI-8859|ensemblfungi:YKL189W|uniprotkb:D6VX11	intact:EBI-11524851|ensembl:ENSP00000368249|ensembl:ENSP00000480148	psi-mi:hym1_yeast(display_long)|uniprotkb:YKL189W(locus name)|uniprotkb:HYM1(gene name)|psi-mi:HYM1(display_short)	psi-mi:q8na61-2(display_long)|uniprotkb:CBY2(gene name)|psi-mi:CBY2(display_short)|uniprotkb:SPERT(gene name synonym)|uniprotkb:Spermatid-associated protein(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11525511|imex:IM-24995-332	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YKL189W(gene)|ensemblfungi:YKL189W_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0000920"(septum digestion after cytokinesis)|go:"GO:0005933"(cellular bud)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007118"(budding cell apical bud growth)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043332"(mating projection tip)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0044732"(mitotic spindle pole body)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013878(Mo25-like)|interpro:IPR016024(Armadillo-type fold)|reactome:R-SCE-6798695|refseq:NP_012732.1|sgd:S000001672|mint:P32464|dip:DIP-5425N|sgd:YKL189W(identity)	intact:EBI-741724(isoform-parent)|ensembl:ENSG00000174015(gene)|ensembl:ENST00000378966(transcript)|ensembl:ENST00000610924(transcript)|uniprotkb:Q8NA61-2(isoform-parent)|entrezgene/locuslink:220082(identity)	-	crc64:F48860754C892BA9	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:pOlQFFuYgFzmqf3ZGUVkBj9h7Uc559292	rogid:SogYcXGGMYRYzB9xKC5o0pEtsDs9606	intact-crc:60D3771EEB398581|rigid:C9ytOIqS0AwNc/ow8UyMDpknYcQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32464	uniprotkb:Q9BRK4	intact:EBI-8859|ensemblfungi:YKL189W|uniprotkb:D6VX11	intact:EBI-741037|ensembl:ENSP00000359240|ensembl:ENSP00000359243|uniprotkb:Q8N3I0|uniprotkb:Q96J79|uniprotkb:Q96JL2|uniprotkb:B1AL14|uniprotkb:D3DR72	psi-mi:hym1_yeast(display_long)|uniprotkb:YKL189W(locus name)|uniprotkb:HYM1(gene name)|psi-mi:HYM1(display_short)	psi-mi:lzts2_human(display_long)|uniprotkb:Protein LAPSER1(gene name synonym)|uniprotkb:LZTS2(gene name)|psi-mi:LZTS2(display_short)|uniprotkb:KIAA1813(gene name synonym)|uniprotkb:LAPSER1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11525520|imex:IM-24995-333	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YKL189W(gene)|ensemblfungi:YKL189W_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0000920"(septum digestion after cytokinesis)|go:"GO:0005933"(cellular bud)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007118"(budding cell apical bud growth)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043332"(mating projection tip)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0044732"(mitotic spindle pole body)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013878(Mo25-like)|interpro:IPR016024(Armadillo-type fold)|reactome:R-SCE-6798695|refseq:NP_012732.1|sgd:S000001672|mint:P32464|dip:DIP-5425N|sgd:YKL189W(identity)	refseq:NP_115805.1|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030496"(midbody)|go:"GO:0031982"(vesicle)|go:"GO:0051013"(microtubule severing)|go:"GO:0051168"(nuclear export)|go:"GO:0051255"(spindle midzone assembly)|go:"GO:0060682"(primary ureteric bud growth)|go:"GO:0072197"(ureter morphogenesis)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|interpro:IPR028597|mint:Q9BRK4|ensembl:ENSG00000107816(gene)|ensembl:ENST00000370220(transcript)|ensembl:ENST00000370223(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0008285"(negative regulation of cell population proliferation)|refseq:XP_016872269.1|refseq:NP_001305028.1|refseq:NP_001305029.1|refseq:NP_001305030.1|refseq:XP_005270279.1|entrezgene/locuslink:84445(identity)	-	crc64:F48860754C892BA9	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:pOlQFFuYgFzmqf3ZGUVkBj9h7Uc559292	rogid:OaMJmnmfm6JniKUJeyg7fS6zRcw9606	intact-crc:30C07025D4B453BB|rigid:mGzOaKzCbGqGbkKZDZDgf+WUa10	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32502	uniprotkb:Q8N5R6	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	intact:EBI-740841|intact:EBI-953781|uniprotkb:B3KQ49|uniprotkb:A8K3U4|uniprotkb:A8MPQ6|uniprotkb:A8MV61|uniprotkb:A8MVU9|uniprotkb:Q9H5Q6|uniprotkb:Q8TAX6|intact:EBI-2320546|intact:EBI-11522976	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:ccd33_human(display_long)|uniprotkb:CCDC33(gene name)|psi-mi:CCDC33(display_short)|uniprotkb:Cancer/testis antigen 61(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11525566|imex:IM-24995-338	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	refseq:NP_079331.3|interpro:IPR000008(C2 calcium-dependent membrane targeting)|go:"GO:0005777"(peroxisome)|refseq:NP_001274110.1|refseq:NP_877592.2|mint:Q8N5R6|interpro:IPR035892|interpro:IPR039889|entrezgene/locuslink:80125(identity)	-	crc64:A5409FAF1594854C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2021/11/30	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	rogid:eEIn7pQyfdHWx8TeLJpYy0i/gww9606	intact-crc:643944CFB4E91D8F|rigid:5jyzF2xloZxY9H2TFqrNqEYTXQA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9P286	uniprotkb:P32474	intact:EBI-741896|ensembl:ENSP00000322957|ensembl:ENSP00000367679|ensembl:ENSP00000367686|intact:EBI-1051061|uniprotkb:A8K5T6|uniprotkb:D3DW14|uniprotkb:Q5W115|uniprotkb:Q8TB93|uniprotkb:Q9BX09|uniprotkb:Q9ULF6	intact:EBI-2343998|uniprotkb:D6VTD9|uniprotkb:E9P901|ensemblfungi:YDR518W	psi-mi:pak5_human(display_long)|uniprotkb:PAK5(gene name)|psi-mi:PAK5(display_short)|uniprotkb:KIAA1264(gene name synonym)|uniprotkb:PAK7(gene name synonym)|uniprotkb:p21-activated kinase 5(gene name synonym)|uniprotkb:p21-activated kinase 7(gene name synonym)	psi-mi:eug1_yeast(display_long)|uniprotkb:EUG1(gene name)|psi-mi:EUG1(display_short)|uniprotkb:Endoplasmic reticulum protein EUG1(gene name synonym)|uniprotkb:D9719.23(orf name)|uniprotkb:YDR518W(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11525538|imex:IM-24995-335	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000101349(gene)|go:"GO:0045202"(synapse)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR028754|interpro:IPR033923|interpro:IPR036936|rcsb pdb:2F57|reactome:R-HSA-428540|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013405|reactome:R-HSA-9013407|go:"GO:0043408"(regulation of MAPK cascade)|ensembl:ENST00000353224(transcript)|ensembl:ENST00000378423(transcript)|ensembl:ENST00000378429(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007165"(signal transduction)|go:"GO:0007612"(learning)|go:"GO:0007613"(memory)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016477"(cell migration)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0035556"(intracellular signal transduction)|refseq:NP_065074.1|refseq:NP_817127.1|refseq:XP_016883449.1|refseq:XP_016883450.1|refseq:XP_016883451.1|refseq:XP_016883452.1|refseq:XP_016883453.1|refseq:XP_016883454.1|entrezgene/locuslink:57144(identity)	refseq:NP_010806.1|sgd:S000002926|interpro:IPR005792(Protein disulphide isomerase)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR036249|ensemblfungi:YDR518W(gene)|ensemblfungi:YDR518W_mRNA(transcript)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006457"(protein folding)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0019153"("protein-disulfide reductase (glutathione) activity")|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0051082"(unfolded protein binding)|sgd:YDR518W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2017/06/28	rogid:xxNDwmHn4jv8toBmviGjFwBU32E9606	rogid:HGjMgN6bwOoRQeGJ4/p/rM1ay1g559292	intact-crc:B8B0345BC44F0172|rigid:5tzMT9/FZi944PcoXr1XnJ9v9mA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32477	uniprotkb:Q86UW9	intact:EBI-7910|uniprotkb:D6VW83|ensemblfungi:YJL101C	intact:EBI-740376|uniprotkb:Q96H69|uniprotkb:Q9H890|uniprotkb:Q9P200|uniprotkb:Q6XM88|ensembl:ENSP00000322885|ensembl:ENSP00000390218|ensembl:ENSP00000411986|uniprotkb:Q6XM87|intact:EBI-10192429|uniprotkb:Q4ZH49	psi-mi:gsh1_yeast(display_long)|uniprotkb:GSH1(gene name)|psi-mi:GSH1(display_short)|uniprotkb:YJL101C(locus name)|uniprotkb:J0832(orf name)|uniprotkb:Gamma-glutamylcysteine synthetase(gene name synonym)|uniprotkb:Gamma-ECS(gene name synonym)	psi-mi:dtx2_human(display_long)|uniprotkb:RING finger protein 58(gene name synonym)|uniprotkb:DTX2(gene name)|psi-mi:DTX2(display_short)|uniprotkb:KIAA1528(gene name synonym)|uniprotkb:RNF58(gene name synonym)|uniprotkb:Protein deltex-2(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase DTX2(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11525547|imex:IM-24995-336	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012434.1|sgd:S000003637|interpro:IPR004308(Glutamate-cysteine ligase catalytic subunit)|rcsb pdb:3IG5|rcsb pdb:3IG8|rcsb pdb:3LVV|rcsb pdb:3LVW|interpro:IPR014746(Glutamine synthetase/guanido kinase, catalytic region)|ensemblfungi:YJL101C(gene)|ensemblfungi:YJL101C_mRNA(transcript)|go:"GO:0004357"(glutamate-cysteine ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006750"(glutathione biosynthetic process)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0046686"(response to cadmium ion)|sgd:YJL101C(identity)	refseq:NP_001096064.1|refseq:NP_001096065.1|refseq:NP_001096066.1|refseq:NP_065943.2|ensembl:ENSP00000322885|ensembl:ENSP00000390218|ensembl:ENSP00000411986|ensembl:ENST00000446820|ensembl:ENSP00000392545|ensembl:ENSG00000091073(gene)|ensembl:ENST00000324432(transcript)|ensembl:ENST00000413936(transcript)|ensembl:ENST00000430490(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031965"(nuclear membrane)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR004170(WWE)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR018123|interpro:IPR018957|interpro:IPR037197|interpro:IPR039396|interpro:IPR039398|interpro:IPR039399|mint:Q86UW9|rcsb pdb:6IR0|rcsb pdb:6Y22|rcsb pdb:6Y2X|rcsb pdb:6Y3J|reactome:R-HSA-2122948|refseq:XP_011514074.1|refseq:XP_011514075.1|refseq:XP_011514076.1|refseq:XP_011514077.1|refseq:XP_005250188.1|refseq:XP_005250189.1|refseq:XP_016867212.1|refseq:XP_016867213.1|refseq:XP_016867214.1|refseq:XP_016867215.1|refseq:XP_016867216.1|entrezgene/locuslink:113878(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:83EkWwY4UUf7Rvoxtj6HiUr/uHE559292	rogid:ugnjqAbG6Ekyc8MGugCnjc9zVaI9606	intact-crc:867F7D2E48B60C2F|rigid:Tf2s0BnZ1YD0Jp6k+Nk+tDfHNzM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32497	uniprotkb:P26641	intact:EBI-8965|ensemblfungi:YMR309C|uniprotkb:D6W0D6	intact:EBI-351467|uniprotkb:Q6PJ62|uniprotkb:Q6PK31|uniprotkb:Q96CU2|uniprotkb:Q9P196|intact:EBI-2321928|uniprotkb:B4DTG2|ensembl:ENSP00000331901	psi-mi:eif3c_yeast(display_long)|uniprotkb:NIP1(gene name)|psi-mi:NIP1(display_short)|uniprotkb:YMR309C(locus name)|uniprotkb:YM9924.01C(orf name)|uniprotkb:YM9952.11C(orf name)|uniprotkb:Eukaryotic translation initiation factor 3 93 kDa subunit(gene name synonym)|uniprotkb:Nuclear transport protein NIP1(gene name synonym)|uniprotkb:Translation initiation factor eIF3, p93 subunit(gene name synonym)	psi-mi:ef1g_human(display_long)|uniprotkb:PRO1608(orf name)|uniprotkb:EEF1G(gene name)|psi-mi:EEF1G(display_short)|uniprotkb:EF1G(gene name synonym)|uniprotkb:eEF-1B gamma(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11525557|imex:IM-24995-337	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|ensemblfungi:YMR309C(gene)|ensemblfungi:YMR309C_mRNA(transcript)|go:"GO:0006413"(translational initiation)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0043614"(multi-eIF complex)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR008905(Eukaryotic translation initiation factor 3 subunit 8, N-terminal)|interpro:IPR027516|rcsb pdb:3JAP|rcsb pdb:4U1C|rcsb pdb:5H7U|rcsb pdb:6FYX|rcsb pdb:6FYY|rcsb pdb:6GSM|rcsb pdb:6GSN|rcsb pdb:6ZCE|rcsb pdb:6ZU9|reactome:R-SCE-156827|reactome:R-SCE-72649|reactome:R-SCE-72695|reactome:R-SCE-72702|refseq:NP_014040.1|sgd:S000004926|mint:P32497|dip:DIP-1470N|sgd:YMR309C(identity)	refseq:NP_001395.1|ensembl:ENSG00000254772(gene)|ensembl:ENST00000329251(transcript)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006414"(translational elongation)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001662(Translation elongation factor EF1B, gamma chain, conserved)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR036249|interpro:IPR036282|interpro:IPR036433|interpro:IPR040079|mint:P26641|rcsb pdb:1PBU|rcsb pdb:5DQS|rcsb pdb:5JPO|reactome:R-HSA-156842|dip:DIP-32516N|entrezgene/locuslink:1937(identity)	-	crc64:EE05097C44C45A4C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:D2B5DHNCbowAIRjWdoxAkeP/CXk559292	rogid:biVN96umeEdPm/wvPN4VwbSRHTs9606	intact-crc:B78E651D4044B9AD|rigid:UDC3Tvp+dHT39OFxJPk6nv7LHOc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:A0A0R4J2E4	uniprotkb:P32502	intact:EBI-11525602|ensembl:ENSP00000324292	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:a0a0r4j2e4_human(display_long)|uniprotkb:FBF1(gene name)|psi-mi:FBF1(display_short)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11525600|imex:IM-24995-341	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000188878(gene)|ensembl:ENST00000319129(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0060271"(cilium assembly)|go:"GO:0090162"(establishment of epithelial cell polarity)|go:"GO:0097539"(ciliary transition fiber)|interpro:IPR033561|entrezgene/locuslink:85302(identity)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	-	-	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/03/16	rogid:N4h8foiP1+HSYZRE7i66zhtqKlQ9606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:B43EF1F765DE2BA1|rigid:o1ADKMU+Hf56w0Mn/5d6v5jxhCA	false	sufficient binding region:649-1092	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
intact:EBI-11525577	uniprotkb:P32502	-	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:pde4dip(display_short)|psi-mi:EBI-11525577(display_long)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11525575|imex:IM-24995-339	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	entrezgene/locuslink:9659(identity)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	-	no-uniprot-update:	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:1FG5rtwoLqpyiNu81cqSpFdaXDY9606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:23577A8EE5D62D8E|rigid:3PkRr2VqTLqLOCdfIfBqDQ8Hk2E	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32502	uniprotkb:A0A0C4DFM0	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	intact:EBI-11525587|ensembl:ENSP00000216465	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:a0a0c4dfm0_human(display_long)|uniprotkb:hCG_22265(orf name)|uniprotkb:GSTZ1(gene name)|psi-mi:GSTZ1(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11525591|imex:IM-24995-340	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	refseq:NP_665877.1|ensembl:ENSG00000100577(gene)|ensembl:ENST00000216465(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0006559"(L-phenylalanine catabolic process)|go:"GO:0006572"(tyrosine catabolic process)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0016034"(maleylacetoacetate isomerase activity)|go:"GO:0016740"(transferase activity)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR005955(Maleylacetoacetate isomerase)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR034330|interpro:IPR034333|interpro:IPR036249|interpro:IPR036282|interpro:IPR040079|entrezgene/locuslink:2954(identity)	-	crc64:A5409FAF1594854C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	rogid:kAk3W6wTlhMKasX8CzDxF6U5/jc9606	intact-crc:9D1955092FE441C2|rigid:8sFEQIVUuAUQLaGakM51sY13Xcs	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:I6L8A6	uniprotkb:P32502	intact:EBI-11525639|ensembl:ENSP00000354024	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:i6l8a6_human(display_long)|uniprotkb:DNA endonuclease RBBP8(gene name synonym)|uniprotkb:RBBP8(gene name)|psi-mi:RBBP8(display_short)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11525643|imex:IM-24995-344	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000101773(gene)|ensembl:ENST00000360790(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003677"(DNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0010792"(DNA double-strand break processing involved in repair via single-strand annealing)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|interpro:IPR013882(DNA repair protein Sae2)|interpro:IPR019518|interpro:IPR033316|interpro:IPR033594|entrezgene/locuslink:5932(identity)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	-	-	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:GHiZbuwZR+0GRaqg0vt6Dsg4pCk9606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:2D372EA6D5AA43DD|rigid:9aDIyPR3htM3T7hxoOi2T6lRyt0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32502	uniprotkb:G5E962	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	intact:EBI-11525615|ensembl:ENSP00000328177	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:g5e962_human(display_long)|uniprotkb:hCG_1644200(orf name)|uniprotkb:MAGEA11(gene name)|psi-mi:MAGEA11(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11525613|imex:IM-24995-342	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	refseq:NP_001011544.1|ensembl:ENSG00000185247(gene)|ensembl:ENST00000333104(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016604"(nuclear body)|interpro:IPR002190(MAGE protein)|interpro:IPR021072|interpro:IPR030099|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|entrezgene/locuslink:4110(identity)	-	crc64:A5409FAF1594854C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	rogid:sVB0aA6yibWUx/d2SE+pwpKKgtI9606	intact-crc:70D28BFE137C711E|rigid:6aq7Xa/T42Sl2M+Fq5wpd1aNTio	false	-	sufficient binding region:82-400	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q7Z6G3-2	uniprotkb:P32502	intact:EBI-10172876|ensembl:ENSP00000457354|intact:EBI-14062040	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:q7z6g3-2(display_long)|uniprotkb:EFCBP2(gene name synonym)|uniprotkb:Neuronal calcium-binding protein 2(gene name synonym)|uniprotkb:Synaptotagmin-interacting protein 2(gene name synonym)|uniprotkb:NECAB2(gene name)|psi-mi:NECAB2(display_short)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11525628|imex:IM-24995-343	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000103154(gene)|ensembl:ENST00000565691(transcript)|uniprotkb:Q7Z6G3-2(isoform-parent)|intact:EBI-950070(isoform-parent)|entrezgene/locuslink:54550(identity)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	-	-	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:4S7oIx6h+mKzV3EPxqcfMNqaNko9606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:12DA86477B605BCC|rigid:83Cnms/xtYhuLT9dx6N+G4rH+m0	false	sufficient binding region:65-303	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O15156-2	uniprotkb:P32502	intact:EBI-11522250|ensembl:ENSP00000406286	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:o15156-2(display_long)|uniprotkb:ZBTB7B(gene name)|psi-mi:ZBTB7B(display_short)|uniprotkb:Krueppel-related zinc finger protein cKrox(gene name synonym)|uniprotkb:T-helper-inducing POZ/Krueppel-like factor(gene name synonym)|uniprotkb:ZBTB15(gene name synonym)|uniprotkb:ZFP67(gene name synonym)|uniprotkb:ZNF857B(gene name synonym)|uniprotkb:Zinc finger and BTB domain-containing protein 15(gene name synonym)|uniprotkb:Zinc finger protein 67 homolog(gene name synonym)|uniprotkb:Zinc finger protein 857B(gene name synonym)|uniprotkb:Zinc finger protein Th-POK(gene name synonym)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11525670|imex:IM-24995-347	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-740434(isoform-parent)|ensembl:ENSG00000160685(gene)|ensembl:ENST00000417934(transcript)|uniprotkb:O15156-2(isoform-parent)|entrezgene/locuslink:51043(identity)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	-	isoform-comment:No experimental confirmation available.	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:41NEFYyprTXI+fOHVFh78TPKF289606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:9D9BEC0EEF3AC761|rigid:/+UmWdQzSLdY3ig1erzXeqIHwFY	false	sufficient binding region:35-573	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32502	uniprotkb:O14641	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	intact:EBI-740850|ensembl:ENSP00000005340|uniprotkb:Q53XM0|uniprotkb:D3DTN3	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:dvl2_human(display_long)|uniprotkb:DSH homolog 2(gene name synonym)|uniprotkb:DVL2(gene name)|psi-mi:DVL2(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11525652|imex:IM-24995-345	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	refseq:NP_004413.1|ensembl:ENSG00000004975(gene)|ensembl:ENST00000005340(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005109"(frizzled binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0007507"(heart development)|go:"GO:0016235"(aggresome)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044340"(canonical Wnt signaling pathway involved in regulation of cell proliferation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0150012"(positive regulation of neuron projection arborization)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008341(Dishevelled-2 region)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:O14641|rcsb pdb:2REY|rcsb pdb:3CBX|rcsb pdb:3CBY|rcsb pdb:3CBZ|rcsb pdb:3CC0|rcsb pdb:4WIP|rcsb pdb:5LNP|rcsb pdb:5SUY|rcsb pdb:5SUZ|rcsb pdb:6IW3|rcsb pdb:6JCK|reactome:R-HSA-201681|reactome:R-HSA-201688|reactome:R-HSA-2028269|reactome:R-HSA-4086400|reactome:R-HSA-4608870|reactome:R-HSA-4641258|reactome:R-HSA-4641262|reactome:R-HSA-5099900|reactome:R-HSA-5368598|reactome:R-HSA-5663220|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9673324|ensembl:ENSP00000005340|dip:DIP-34433N|entrezgene/locuslink:1856(identity)	-	crc64:A5409FAF1594854C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	rogid:2Vdc8oRnT4Mz/j+EXQXrL3AszOc9606	intact-crc:D6CB654983001DCF|rigid:pm9EJtyO2bHhLP88C1nUq0TAN68	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O14964	uniprotkb:P32502	intact:EBI-740220|uniprotkb:Q9NR36|ensembl:ENSP00000331201|ensembl:ENSP00000504106	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:hgs_human(display_long)|uniprotkb:Protein pp110(gene name synonym)|uniprotkb:Hrs(gene name synonym)|uniprotkb:HGS(gene name)|psi-mi:HGS(display_short)|uniprotkb:HRS(gene name synonym)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11525661|imex:IM-24995-346	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004703.1|dip:DIP-29050N|ensembl:ENSG00000185359(gene)|ensembl:ENST00000329138(transcript)|ensembl:ENST00000676546(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0007165"(signal transduction)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010324"(membrane invagination)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010642"(negative regulation of platelet-derived growth factor receptor signaling pathway)|go:"GO:0016197"(endosomal transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032585"(multivesicular body membrane)|go:"GO:0033565"(ESCRT-0 complex)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043405"(regulation of MAP kinase activity)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072657"(protein localization to membrane)|go:"GO:0097013"(phagocytic vesicle lumen)|go:"GO:1903543"(positive regulation of exosomal secretion)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR002014(VHS)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017073(Ubiquitin binding protein, Hrs/VPS27)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR024641|mint:O14964|rcsb pdb:2D3G|rcsb pdb:3F1I|rcsb pdb:3OBQ|rcsb pdb:3ZYQ|rcsb pdb:4AVX|reactome:R-HSA-182971|reactome:R-HSA-432720|reactome:R-HSA-5689880|reactome:R-HSA-6807004|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8875360|reactome:R-HSA-9013420|reactome:R-HSA-917729|reactome:R-HSA-9635644|reactome:R-HSA-9636383|reactome:R-HSA-9706019|entrezgene/locuslink:9146(identity)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	-	-	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:z/AnREuqEpyJ9/Zj6JFCJCJem1I9606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:31DC3139E9E1BC6A|rigid:i5XcpStCfjaiDLc3pfO7yC2tQhI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O43809	uniprotkb:P32502	intact:EBI-355720|uniprotkb:Q6IB85|uniprotkb:Q6NE84|ensembl:ENSP00000300291	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:cpsf5_human(display_long)|uniprotkb:NUDT21(gene name)|psi-mi:NUDT21(display_short)|uniprotkb:CFIM25(gene name synonym)|uniprotkb:CPSF25(gene name synonym)|uniprotkb:CPSF5(gene name synonym)|uniprotkb:Cleavage and polyadenylation specificity factor 25 kDa subunit(gene name synonym)|uniprotkb:Nucleoside diphosphate-linked moiety X motif 21(gene name synonym)|uniprotkb:Cleavage factor Im complex 25 kDa subunit(gene name synonym)|uniprotkb:Nudix hydrolase 21(gene name synonym)|uniprotkb:Pre-mRNA cleavage factor Im 68 kDa subunit(gene name synonym)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11525699|imex:IM-24995-350	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_008937.1|ensembl:ENSG00000167005(gene)|ensembl:ENST00000300291(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0005849"(mRNA cleavage factor complex)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0006397"(mRNA processing)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0031439"(positive regulation of mRNA cleavage)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0042382"(paraspeckles)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051290"(protein heterotetramerization)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|go:"GO:0110104"(mRNA alternative polyadenylation)|go:"GO:1900365"(positive regulation of mRNA polyadenylation)|go:"GO:1990120"(messenger ribonucleoprotein complex assembly)|go:"GO:2000738"(positive regulation of stem cell differentiation)|go:"GO:2000975"(positive regulation of pro-B cell differentiation)|interpro:IPR000086(NUDIX hydrolase, core)|interpro:IPR015797(NUDIX)|interpro:IPR016706(Cleavage and polyadenylation specificity factor, 25 kDa subunit)|mint:O43809|rcsb pdb:2CL3|rcsb pdb:2J8Q|rcsb pdb:3BAP|rcsb pdb:3BHO|rcsb pdb:3MDG|rcsb pdb:3MDI|rcsb pdb:3N9U|rcsb pdb:3P5T|rcsb pdb:3P6Y|rcsb pdb:3Q2S|rcsb pdb:3Q2T|rcsb pdb:5R4P|rcsb pdb:5R4Q|rcsb pdb:5R4R|rcsb pdb:5R4S|rcsb pdb:5R4T|rcsb pdb:5R4U|rcsb pdb:5R64|rcsb pdb:5R65|rcsb pdb:5R66|rcsb pdb:5R67|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-77595|dip:DIP-42502N|entrezgene/locuslink:11051(identity)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	-	-	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Acad4mYVuS+Eox+X2CH8PYUkGAA9606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:EB1D390E99E04EF4|rigid:BP13JVI+4PVMBrwgCeg4x1bZzTw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O43597	uniprotkb:P32502	intact:EBI-742487|uniprotkb:Q5T6Z7|ensembl:ENSP00000366306|ensembl:ENSP00000366308|uniprotkb:B2R9J9	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:spy2_human(display_long)|uniprotkb:SPRY2(gene name)|psi-mi:SPRY2(display_short)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11525690|imex:IM-24995-349	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005833.1|rcsb pdb:5HL0|reactome:R-HSA-1295596|reactome:R-HSA-182971|rcsb pdb:5HKZ|ensembl:ENST00000377102(transcript)|ensembl:ENST00000377104(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|ensembl:ENSG00000136158(gene)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030291"(protein serine/threonine kinase inhibitor activity)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031345"(negative regulation of cell projection organization)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0032587"(ruffle membrane)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0045165"(cell fate commitment)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048513"(animal organ development)|go:"GO:0051387"(negative regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060437"(lung growth)|go:"GO:0060449"(bud elongation involved in lung branching)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:1900747"(negative regulation of vascular endothelial growth factor signaling pathway)|go:"GO:1902747"(negative regulation of lens fiber cell differentiation)|go:"GO:1990752"(microtubule end)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR007875(Sprouty)|interpro:IPR030780|mint:O43597|rcsb pdb:3BUM|rcsb pdb:3OB1|rcsb pdb:5HKY|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|refseq:NP_001305465.1|refseq:NP_001305466.1|refseq:NP_001305467.1|entrezgene/locuslink:10253(identity)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	-	-	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:u1omauzisc6MdZlogMotUmtauSI9606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:B6572E6549C465A8|rigid:3mEi232CWxAHeNyuaGfgfCcKtHw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O60232	uniprotkb:P32502	intact:EBI-741415|ensembl:ENSP00000312318	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:znrd2_human(display_long)|uniprotkb:ZNRD2(gene name)|psi-mi:ZNRD2(display_short)|uniprotkb:Autoantigen p27(gene name synonym)|uniprotkb:SSSCA1(gene name synonym)|uniprotkb:Sjoegren syndrome/scleroderma autoantigen 1(gene name synonym)|uniprotkb:Zinc ribbon domain-containing protein 2(gene name synonym)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11525708|imex:IM-24995-351	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006387.1|ensembl:ENSG00000173465(gene)|ensembl:ENST00000309328(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0051301"(cell division)|interpro:IPR009563(Sjogrens syndrome scleroderma autoantigen 1)|rcsb pdb:6HCZ|entrezgene/locuslink:10534(identity)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	-	-	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Uou80pZneoL39/0YYzb1TAbiB2I9606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:D512E9DD7102D062|rigid:Mv4bbKj+10EcTY9SVZ16eZ7Fty4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32502	uniprotkb:O75506	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	intact:EBI-748664|uniprotkb:Q7Z5Z3|uniprotkb:Q53XA8|ensembl:ENSP00000392896|ensembl:ENSP00000458007	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:hsbp1_human(display_long)|uniprotkb:Nasopharyngeal carcinoma-associated antigen 13(gene name synonym)|uniprotkb:HSBP1(gene name)|psi-mi:HSBP1(display_short)|uniprotkb:HSF1BP(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11525717|imex:IM-24995-352	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	refseq:NP_001528.1|interpro:IPR009643(Heat shock factor binding 1)|rcsb pdb:3CI9|reactome:R-HSA-3371511|reactome:R-HSA-3371568|reactome:R-HSA-3371571|ensembl:ENSG00000230989(gene)|ensembl:ENST00000433866(transcript)|ensembl:ENST00000570259(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006936"(muscle contraction)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0070370"(cellular heat acclimation)|entrezgene/locuslink:3281(identity)	-	crc64:A5409FAF1594854C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	rogid:3JML7OxHIw8M91ARKPfOhJ9kVbk9606	intact-crc:869CAB0AA5E5A0DB|rigid:dyaEbB+dUfXqlZ1ueee42GVMNUY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O15217	uniprotkb:P32502	intact:EBI-752440|uniprotkb:Q5T7Q8|uniprotkb:Q9BX18|uniprotkb:Q9H414|uniprotkb:B2RD15|uniprotkb:Q6P4G1|ensembl:ENSP00000359998|ensembl:ENSP00000360002	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:gsta4_human(display_long)|uniprotkb:Glutathione S-transferase A4-4(gene name synonym)|uniprotkb:GST class-alpha member 4(gene name synonym)|uniprotkb:GSTA4(gene name)|psi-mi:GSTA4(display_short)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11525681|imex:IM-24995-348	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001503.1|refseq:XP_005249092.1|ensembl:ENSG00000170899(gene)|ensembl:ENST00000370959(transcript)|ensembl:ENST00000370963(transcript)|go:"GO:0004364"(glutathione transferase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0006805"(xenobiotic metabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|interpro:IPR003080(Glutathione S-transferase, alpha class)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR036249|interpro:IPR036282|interpro:IPR040079|rcsb pdb:1GUL|rcsb pdb:1GUM|rcsb pdb:3IK7|reactome:R-HSA-156590|entrezgene/locuslink:2941(identity)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	-	-	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:9yVcqmJL64S0kxOW5RJWbOJ25bo9606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:9CCDC66A41318DF1|rigid:vivFJzLRywr+nlr9ldQiyJabTCY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32502	uniprotkb:O96006	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	intact:EBI-740037|uniprotkb:Q96BY4|ensembl:ENSP00000370616|ensembl:ENSP00000370620|ensembl:ENSP00000370621|ensembl:ENSP00000498725	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:zbed1_human(display_long)|uniprotkb:ZBED1(gene name)|psi-mi:ZBED1(display_short)|uniprotkb:ALTE(gene name synonym)|uniprotkb:DREF(gene name synonym)|uniprotkb:KIAA0785(gene name synonym)|uniprotkb:TRAMP(gene name synonym)|uniprotkb:dREF homolog(gene name synonym)|uniprotkb:Putative Ac-like transposable element(gene name synonym)|uniprotkb:DNA replication-related element-binding factor(gene name synonym)|uniprotkb:Zinc finger BED domain-containing protein 1(gene name synonym)|uniprotkb:hDREF(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11525757|imex:IM-24995-356	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	refseq:NP_001164606.1|refseq:NP_001164607.1|refseq:NP_004720.1|ensembl:ENSG00000214717(gene)|ensembl:ENST00000381218(transcript)|ensembl:ENST00000381222(transcript)|ensembl:ENST00000381223(transcript)|ensembl:ENST00000652001(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0031965"(nuclear membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044828"(negative regulation by host of viral genome replication)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0061665"(SUMO ligase activity)|go:"GO:1990466"(protein autosumoylation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003656(Zinc finger, BED-type predicted)|interpro:IPR008906(HAT dimerisation)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR036236|mint:O96006|rcsb pdb:2CT5|reactome:R-HSA-4551638|go:"GO:0005813"(centrosome)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016605"(PML body)|entrezgene/locuslink:9189(identity)	-	crc64:A5409FAF1594854C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	rogid:jl97ZV2Kz5YAmQKktWt/wk7OkRw9606	intact-crc:3E2CCE335DF86BE0|rigid:xnjMmbDtA3wd0wWMkdA+FSzpBpo	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O76083-2	uniprotkb:P32502	intact:EBI-11524542|ensembl:ENSP00000335242	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:o76083-2(display_long)|uniprotkb:PDE9A(gene name)|psi-mi:PDE9A(display_short)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11525726|imex:IM-24995-353	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-742764(isoform-parent)|ensembl:ENSG00000160191(gene)|ensembl:ENST00000335512(transcript)|uniprotkb:O76083-2(isoform-parent)|entrezgene/locuslink:5152(identity)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	-	-	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:nTzgeYGOwTM/7VJUgxSnlnDiCFo9606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:84CDAD560E05C3F9|rigid:K4ak8/bIDA6IYLzdcaWwFmmTfPg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O95197-3	uniprotkb:P32502	intact:EBI-11525735|ensembl:ENSP00000440874	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:o95197-3(display_long)|uniprotkb:RTN3(gene name)|psi-mi:RTN3(display_short)|uniprotkb:ASYIP(gene name synonym)|uniprotkb:Homolog of ASY protein(gene name synonym)|uniprotkb:NSPL2(gene name synonym)|uniprotkb:Neuroendocrine-specific protein-like 2(gene name synonym)|uniprotkb:Neuroendocrine-specific protein-like II(gene name synonym)|uniprotkb:A1(isoform synonym)|uniprotkb:B1(isoform synonym)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11525739|imex:IM-24995-354	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000133318(gene)|ensembl:ENST00000537981(transcript)|intact:EBI-740467(isoform-parent)|uniprotkb:O95197-3(isoform-parent)|entrezgene/locuslink:10313(identity)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	-	-	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:+TJnANu85CM52dRZ6s+hYMlUABE9606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:8C2835C848091226|rigid:qZKS34xaUps9By4csjsNmwDjfLQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32502	uniprotkb:O95273	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	intact:EBI-748961|uniprotkb:A8K3Q0|uniprotkb:A8K3U2|uniprotkb:Q6ZQN9|uniprotkb:Q7Z519|uniprotkb:Q8NBS7|uniprotkb:Q8NBY2|uniprotkb:Q9NS19|uniprotkb:Q9NYH3|uniprotkb:Q9UHX9|ensembl:ENSP00000300213	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:ccdb1_human(display_long)|uniprotkb:Grap2 and cyclin-D-interacting protein(gene name synonym)|uniprotkb:Human homolog of Maid(gene name synonym)|uniprotkb:CCNDBP1(gene name)|psi-mi:CCNDBP1(display_short)|uniprotkb:DIP1(gene name synonym)|uniprotkb:GCIP(gene name synonym)|uniprotkb:HHM(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11525748|imex:IM-24995-355	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	refseq:NP_036274.3|ensembl:ENSG00000166946(gene)|ensembl:ENST00000300213(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0016604"(nuclear body)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR026907|mint:O95273|rcsb pdb:3AY5|entrezgene/locuslink:23582(identity)	-	crc64:A5409FAF1594854C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	rogid:Vi9aoFc+Mov6P3X6KGmsTxXqxvM9606	intact-crc:20FF8BCB2D9236BE|rigid:aQNC2q2a67Rxblovfqfkg6WAZLM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32502	uniprotkb:P08727	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	intact:EBI-742756|uniprotkb:Q5XG83|uniprotkb:Q6NW33|uniprotkb:Q7L5M9|uniprotkb:Q96A53|uniprotkb:Q96FV1|uniprotkb:Q9BYF9|uniprotkb:Q9P1Y4|uniprotkb:B2R874|ensembl:ENSP00000355124	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:k1c19_human(display_long)|uniprotkb:Cytokeratin-19(gene name synonym)|uniprotkb:Keratin-19(gene name synonym)|uniprotkb:KRT19(gene name)|psi-mi:KRT19(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11525793|imex:IM-24995-360	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	refseq:NP_002267.2|ensembl:ENSG00000171345(gene)|ensembl:ENST00000361566(transcript)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0030018"(Z disc)|go:"GO:0042383"(sarcolemma)|go:"GO:0043034"(costamere)|go:"GO:0043627"(response to estrogen)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0060706"(cell differentiation involved in embryonic placenta development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071944"(cell periphery)|go:"GO:1990357"(terminal web)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR039008|mint:P08727|reactome:R-HSA-6805567|reactome:R-HSA-6809371|dip:DIP-35655N|entrezgene/locuslink:3880(identity)	-	crc64:A5409FAF1594854C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	rogid:fqsG2nghpcmTtI39LiYVLNYuFIA9606	intact-crc:13B04116763C74E7|rigid:GRI60gRVRUUKPM4dUxsitr4Uytg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P00492	uniprotkb:P32502	intact:EBI-748210|uniprotkb:A6NHF0|uniprotkb:B2R8M9|ensembl:ENSP00000298556	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:hprt_human(display_long)|uniprotkb:HPRT1(gene name)|psi-mi:HPRT1(display_short)|uniprotkb:HPRT(gene name synonym)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11525766|imex:IM-24995-357	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000185.1|ensembl:ENSG00000165704(gene)|ensembl:ENST00000298556(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001913"(T cell mediated cytotoxicity)|go:"GO:0001975"(response to amphetamine)|go:"GO:0004422"(hypoxanthine phosphoribosyltransferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006164"(purine nucleotide biosynthetic process)|go:"GO:0006166"(purine ribonucleoside salvage)|go:"GO:0006168"(adenine salvage)|go:"GO:0006178"(guanine salvage)|go:"GO:0007625"(grooming behavior)|go:"GO:0007626"(locomotory behavior)|go:"GO:0021756"(striatum development)|go:"GO:0021895"(cerebral cortex neuron differentiation)|go:"GO:0021954"(central nervous system neuron development)|go:"GO:0032263"(GMP salvage)|go:"GO:0032264"(IMP salvage)|go:"GO:0042417"(dopamine metabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043103"(hypoxanthine salvage)|go:"GO:0045964"(positive regulation of dopamine metabolic process)|go:"GO:0046038"(GMP catabolic process)|go:"GO:0046040"(IMP metabolic process)|go:"GO:0046100"(hypoxanthine metabolic process)|go:"GO:0046651"(lymphocyte proliferation)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0052657"(guanine phosphoribosyltransferase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000836(Phosphoribosyltransferase)|interpro:IPR005904(Hypoxanthine phosphoribosyl transferase)|interpro:IPR029057|mint:P00492|rcsb pdb:1BZY|rcsb pdb:1D6N|rcsb pdb:1HMP|rcsb pdb:1Z7G|go:"GO:0048813"(dendrite morphogenesis)|rcsb pdb:2VFA|rcsb pdb:3GEP|rcsb pdb:3GGC|rcsb pdb:3GGJ|rcsb pdb:4IJQ|rcsb pdb:4KN6|rcsb pdb:4RAB|rcsb pdb:4RAC|rcsb pdb:4RAD|rcsb pdb:4RAN|rcsb pdb:4RAO|rcsb pdb:4RAQ|rcsb pdb:5BRN|rcsb pdb:5BSK|rcsb pdb:5HIA|rcsb pdb:5W8V|rcsb pdb:6BNJ|reactome:R-HSA-74217|entrezgene/locuslink:3251(identity)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	-	-	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:w87Sv/qOAkHFqJm0vu0Ayqlz7TA9606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:5ABE8B690C081236|rigid:PISP8RuaU+d5E5vA27VfIBZftkI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32502	uniprotkb:P04271	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	intact:EBI-458391|ensembl:ENSP00000291700|ensembl:ENSP00000380769|uniprotkb:D3DSN6	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:s100b_human(display_long)|uniprotkb:S100B(gene name)|psi-mi:S100B(display_short)|uniprotkb:S100 calcium-binding protein B(gene name synonym)|uniprotkb:S-100 protein subunit beta(gene name synonym)|uniprotkb:S-100 protein beta chain(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11525775|imex:IM-24995-358	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	ensembl:ENSG00000160307(gene)|ensembl:ENST00000291700(transcript)|ensembl:ENST00000397648(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007409"(axonogenesis)|go:"GO:0007417"(central nervous system development)|go:"GO:0007611"(learning or memory)|go:"GO:0007613"(memory)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0031643"(positive regulation of myelination)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044548"(S100 protein binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0048168"(regulation of neuronal synaptic plasticity)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048708"(astrocyte differentiation)|go:"GO:0050786"(RAGE receptor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0051597"(response to methylmercury)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:2001015"(negative regulation of skeletal muscle cell differentiation)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR018247|interpro:IPR028481|mint:P04271|rcsb pdb:1MQ1|rcsb pdb:1UWO|rcsb pdb:2H61|rcsb pdb:2M49|rcsb pdb:2PRU|rcsb pdb:3CZT|rcsb pdb:3D0Y|rcsb pdb:3D10|rcsb pdb:3HCM|rcsb pdb:4XYN|rcsb pdb:5CSF|rcsb pdb:5CSI|rcsb pdb:5CSJ|rcsb pdb:5CSN|rcsb pdb:5D7F|go:"GO:0051384"(response to glucocorticoid)|reactome:R-HSA-1251985|reactome:R-HSA-445989|reactome:R-HSA-879415|reactome:R-HSA-933542|refseq:NP_006263.1|refseq:XP_016883913.1|entrezgene/locuslink:6285(identity)	-	crc64:A5409FAF1594854C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	rogid:e6p9zHV5sa8+lIZgYW1aiAAfq3s9606	intact-crc:14CF6513458C2BCC|rigid:R0s2qnF0R4cHOZOdmXpPr9Eil5U	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32502	uniprotkb:P07910-2	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	intact:EBI-5280084|ensembl:ENSP00000442816|ensembl:ENSP00000450544|ensembl:ENSP00000450725|ensembl:ENSP00000451176	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:p07910-2(display_long)|uniprotkb:HNRNPC(gene name)|psi-mi:HNRNPC(display_short)|uniprotkb:HNRPC(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11525784|imex:IM-24995-359	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	uniprotkb:P07910-2(isoform-parent)|intact:EBI-357966(isoform-parent)|ensembl:ENSG00000092199(gene)|ensembl:ENST00000430246(transcript)|ensembl:ENST00000553300(transcript)|ensembl:ENST00000554969(transcript)|ensembl:ENST00000556897(transcript)|entrezgene/locuslink:3183(identity)	-	crc64:A5409FAF1594854C	isoform-comment:Contains a phosphoserine at position 107. Contains a phosphoserine at position 108.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	rogid:r7AhGozE3aHdynLr8DrXPRtOuyI9606	intact-crc:577067C7FD8869F8|rigid:1cqi50rFIN9YGgs3/g3Rad18Oyk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32502	uniprotkb:P20591	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	intact:EBI-929476|uniprotkb:D3DSI8|uniprotkb:B2RDA5|uniprotkb:B3KU10|uniprotkb:C9IYV7|uniprotkb:C9J8D6|uniprotkb:C9JN19|uniprotkb:C9JN88|uniprotkb:C9JUL1|uniprotkb:C9JZS6|uniprotkb:Q86YP5|uniprotkb:Q96CI3|ensembl:ENSP00000381599|ensembl:ENSP00000381601|ensembl:ENSP00000392151|ensembl:ENSP00000402215|ensembl:ENSP00000408498|ensembl:ENSP00000410523|ensembl:ENSP00000505029|ensembl:ENSP00000505047|ensembl:ENSP00000505051|ensembl:ENSP00000505189|ensembl:ENSP00000505457|ensembl:ENSP00000505489|ensembl:ENSP00000505630|ensembl:ENSP00000505657|ensembl:ENSP00000505669|ensembl:ENSP00000505781|ensembl:ENSP00000505874|ensembl:ENSP00000506047|ensembl:ENSP00000506062|ensembl:ENSP00000506183|ensembl:ENSP00000506199|ensembl:ENSP00000506220|ensembl:ENSP00000506270|ensembl:ENSP00000506348|ensembl:ENSP00000506372|ensembl:ENSP00000506395|ensembl:ENSP00000506481|ensembl:ENSP00000506512|ensembl:ENSP00000506690|ensembl:ENSP00000506712	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:mx1_human(display_long)|uniprotkb:MX1(gene name)|psi-mi:MX1(display_short)|uniprotkb:Myxovirus resistance protein 1(gene name synonym)|uniprotkb:Interferon-regulated resistance GTP-binding protein MxA(gene name synonym)|uniprotkb:Interferon-induced protein p78(gene name synonym)|uniprotkb:Myxoma resistance protein 1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11525838|imex:IM-24995-365	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	refseq:NP_001269849.1|refseq:NP_001138397.1|refseq:NP_001171517.1|refseq:NP_002453.2|refseq:XP_011527870.1|refseq:XP_005261037.1|refseq:XP_005261038.1|refseq:XP_005261039.1|refseq:XP_005261035.1|refseq:XP_005261036.1|refseq:XP_016883838.1|refseq:XP_016883839.1|dip:DIP-35694N|ensembl:ENSG00000157601(gene)|ensembl:ENST00000398598(transcript)|ensembl:ENST00000398600(transcript)|ensembl:ENST00000413778(transcript)|ensembl:ENST00000417963(transcript)|ensembl:ENST00000419044(transcript)|ensembl:ENST00000455164(transcript)|ensembl:ENST00000679445(transcript)|ensembl:ENST00000679464(transcript)|ensembl:ENST00000679543(transcript)|ensembl:ENST00000679626(transcript)|ensembl:ENST00000679705(transcript)|ensembl:ENST00000679911(transcript)|ensembl:ENST00000680176(transcript)|ensembl:ENST00000680182(transcript)|ensembl:ENST00000680347(transcript)|ensembl:ENST00000680364(transcript)|ensembl:ENST00000680536(transcript)|ensembl:ENST00000680629(transcript)|ensembl:ENST00000680760(transcript)|ensembl:ENST00000680776(transcript)|ensembl:ENST00000681039(transcript)|ensembl:ENST00000681191(transcript)|ensembl:ENST00000681266(transcript)|ensembl:ENST00000681415(transcript)|ensembl:ENST00000681607(transcript)|ensembl:ENST00000681671(transcript)|ensembl:ENST00000681849(transcript)|ensembl:ENST00000681857(transcript)|ensembl:ENST00000681867(transcript)|ensembl:ENST00000681896(transcript)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0003374"(dynamin family protein polymerization involved in mitochondrial fission)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0006952"(defense response)|go:"GO:0007165"(signal transduction)|go:"GO:0008017"(microtubule binding)|go:"GO:0009615"(response to virus)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016185"(synaptic vesicle budding from presynaptic endocytic zone membrane)|go:"GO:0030424"(axon)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031623"(receptor internalization)|go:"GO:0031965"(nuclear membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0034340"(response to type I interferon)|go:"GO:0042802"(identical protein binding)|go:"GO:0044327"(dendritic spine head)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0051607"(defense response to virus)|go:"GO:0061025"(membrane fusion)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:0098793"(presynapse)|go:"GO:0098844"(postsynaptic endocytic zone membrane)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:0140374"(antiviral innate immune response)|interpro:IPR000375(Dynamin central region)|interpro:IPR001401(Dynamin, GTPase region)|interpro:IPR003130(Dynamin GTPase effector)|interpro:IPR019762|interpro:IPR020850|interpro:IPR022812|interpro:IPR027417|interpro:IPR030381|mint:P20591|rcsb pdb:3LJB|rcsb pdb:3SZR|rcsb pdb:3ZYS|rcsb pdb:4P4S|rcsb pdb:4P4T|rcsb pdb:4P4U|rcsb pdb:5GTM|reactome:R-HSA-1169408|reactome:R-HSA-909733|entrezgene/locuslink:4599(identity)	-	crc64:A5409FAF1594854C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	rogid:9rO7Zyl6v0Kq3xw6MKbVefk1hCA9606	intact-crc:386CCECDA213960F|rigid:zxPv0WONMV/801GzpWcMFh0tNEk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P19012	uniprotkb:P32502	intact:EBI-739566|uniprotkb:Q53XV8|uniprotkb:Q9BUG4|uniprotkb:B3KQY1|uniprotkb:B3KRA2|uniprotkb:E0CX14|ensembl:ENSP00000254043|ensembl:ENSP00000377546	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:k1c15_human(display_long)|uniprotkb:KRT15(gene name)|psi-mi:KRT15(display_short)|uniprotkb:KRTB(gene name synonym)|uniprotkb:Cytokeratin-15(gene name synonym)|uniprotkb:Keratin-15(gene name synonym)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11525829|imex:IM-24995-364	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002266.2|ensembl:ENSG00000171346(gene)|ensembl:ENST00000254043(transcript)|ensembl:ENST00000393976(transcript)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0008544"(epidermis development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097110"(scaffold protein binding)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR039008|mint:P19012|reactome:R-HSA-6805567|reactome:R-HSA-6809371|entrezgene/locuslink:3866(identity)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	-	-	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:WrZQBYQvrWcfrR5ojWXrXp6spPE9606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:DA211BF9AB11A9AD|rigid:0gvENk/O19qCoFW25bO+8k1LDdA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P14174	uniprotkb:P32502	intact:EBI-372712|uniprotkb:A5Z1R8|uniprotkb:B2R4S3|uniprotkb:Q6FHV0|uniprotkb:Q2V4Y5|ensembl:ENSP00000215754|ensembl:ENSP00000482779	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:mif_human(display_long)|uniprotkb:MIF(gene name)|psi-mi:MIF(display_short)|uniprotkb:MMIF(gene name synonym)|uniprotkb:GLIF(gene name synonym)|uniprotkb:Phenylpyruvate tautomerase(gene name synonym)|uniprotkb:Glycosylation-inhibiting factor(gene name synonym)|uniprotkb:L-dopachrome tautomerase(gene name synonym)|uniprotkb:L-dopachrome isomerase(gene name synonym)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11525802|imex:IM-24995-361	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002406.1|ensembl:ENST00000215754(transcript)|ensembl:ENST00000613839(transcript)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0004167"(dopachrome isomerase activity)|go:"GO:0005125"(cytokine activity)|go:"GO:0005126"(cytokine receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|ensembl:ENSG00000276701(gene)|go:"GO:0006954"(inflammatory response)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0009986"(cell surface)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010739"(positive regulation of protein kinase A signaling)|go:"GO:0010760"(negative regulation of macrophage chemotaxis)|go:"GO:0019752"(carboxylic acid metabolic process)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031982"(vesicle)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042056"(chemoattractant activity)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043030"(regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|ensembl:ENSG00000240972(gene)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045087"(innate immune response)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0050178"(phenylpyruvate tautomerase activity)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070207"(protein homotrimerization)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0090344"(negative regulation of cell aging)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR001398(Macrophage migration inhibitory factor)|interpro:IPR014347(Tautomerase)|interpro:IPR019829|mint:P14174|rcsb pdb:1CGQ|rcsb pdb:1GCZ|rcsb pdb:1GD0|rcsb pdb:1GIF|rcsb pdb:1LJT|rcsb pdb:1MIF|rcsb pdb:1P1G|rcsb pdb:2OOH|rcsb pdb:2OOW|rcsb pdb:2OOZ|rcsb pdb:3B9S|rcsb pdb:3CE4|rcsb pdb:3DJH|rcsb pdb:3DJI|rcsb pdb:3HOF|rcsb pdb:3IJG|rcsb pdb:3IJJ|rcsb pdb:3JSF|rcsb pdb:3JSG|rcsb pdb:3JTU|rcsb pdb:3L5P|rcsb pdb:3L5R|rcsb pdb:3L5S|rcsb pdb:3L5T|rcsb pdb:3L5U|rcsb pdb:3L5V|rcsb pdb:3SMB|rcsb pdb:3SMC|rcsb pdb:3U18|rcsb pdb:3WNR|rcsb pdb:3WNS|rcsb pdb:3WNT|rcsb pdb:4ETG|rcsb pdb:4EUI|rcsb pdb:4EVG|rcsb pdb:4F2K|rcsb pdb:4GRN|rcsb pdb:4GRO|rcsb pdb:4GRP|rcsb pdb:4GRQ|rcsb pdb:4GRR|rcsb pdb:4GRU|rcsb pdb:4GUM|rcsb pdb:4K9G|rcsb pdb:4OSF|rcsb pdb:4OYQ|rcsb pdb:4P01|rcsb pdb:4P0H|rcsb pdb:4PKK|rcsb pdb:4PKZ|rcsb pdb:4PLU|rcsb pdb:4TRF|rcsb pdb:4TRU|rcsb pdb:4WR8|rcsb pdb:4WRB|rcsb pdb:4XX7|rcsb pdb:4XX8|rcsb pdb:4Z15|rcsb pdb:4Z1T|rcsb pdb:4Z1U|rcsb pdb:5B4O|rcsb pdb:5BS9|rcsb pdb:5BSC|rcsb pdb:5BSI|rcsb pdb:5BSJ|rcsb pdb:5EIZ|rcsb pdb:5HVS|rcsb pdb:5HVT|rcsb pdb:5HVV|rcsb pdb:5J7P|rcsb pdb:5J7Q|rcsb pdb:5UMJ|rcsb pdb:5UMK|rcsb pdb:5UZY|rcsb pdb:5V70|rcsb pdb:5V73|rcsb pdb:5XEJ|rcsb pdb:1CA7|rcsb pdb:6B1C|rcsb pdb:6B1K|rcsb pdb:6B2C|rcsb pdb:6BG6|rcsb pdb:6BG7|rcsb pdb:6CB5|rcsb pdb:6CBF|rcsb pdb:6CBG|rcsb pdb:6FVE|rcsb pdb:6FVH|rcsb pdb:6OY8|rcsb pdb:6OYB|rcsb pdb:6OYE|rcsb pdb:6OYG|rcsb pdb:6PEG|reactome:R-HSA-202733|reactome:R-HSA-6798695|reactome:R-HSA-8950505|rcsb pdb:6CBH|dip:DIP-31137N|entrezgene/locuslink:4282(identity)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	-	-	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Vk+Sfaz5c59y8dKKJ4Qn+7fjwvQ9606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:87A66230D0B86312|rigid:e777KalAyYVYYod1TcXejrZ/0h0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32502	uniprotkb:P14373	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	intact:EBI-719493|uniprotkb:A2BE15|uniprotkb:Q5RJA8|uniprotkb:Q5ST26|uniprotkb:Q6LA73|uniprotkb:Q6NXR9|uniprotkb:Q9BZY6|uniprotkb:Q9UJL3|ensembl:ENSP00000383555|ensembl:ENSP00000392787|ensembl:ENSP00000405229|ensembl:ENSP00000414793|ensembl:ENSP00000366404	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:tri27_human(display_long)|uniprotkb:TRIM27(gene name)|psi-mi:TRIM27(display_short)|uniprotkb:RNF76(gene name synonym)|uniprotkb:RFP(gene name synonym)|uniprotkb:Ret finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 27(gene name synonym)|uniprotkb:RING finger protein 76(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM27(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11525811|imex:IM-24995-362	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	refseq:NP_006501.1|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0090281"(negative regulation of calcium ion import)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR020457|interpro:IPR035791|interpro:IPR043136|mint:P14373|reactome:R-HSA-3232142|reactome:R-HSA-9635465|reactome:R-HSA-8948751|ensembl:ENSG00000204713(gene)|ensembl:ENSG00000215641(gene)|ensembl:ENSG00000229006(gene)|ensembl:ENSG00000234495(gene)|ensembl:ENSG00000237071(gene)|ensembl:ENST00000377199(transcript)|ensembl:ENST00000400720(transcript)|ensembl:ENST00000431123(transcript)|ensembl:ENST00000435528(transcript)|ensembl:ENST00000437160(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001650"(fibrillar center)|go:"GO:0002820"(negative regulation of adaptive immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|entrezgene/locuslink:5987(identity)	-	crc64:A5409FAF1594854C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	rogid:dsfH5OUghD8KSaTz1SFw9OYVTK49606	intact-crc:A20B007B37210619|rigid:8TmBF4FZuoTGdTF2GdyM2n5jne4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32502	uniprotkb:P15531	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	intact:EBI-741141|ensembl:ENSP00000376892|uniprotkb:Q6FGK3|uniprotkb:Q86XQ2|uniprotkb:Q9UDJ6	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:ndka_human(display_long)|uniprotkb:Tumor metastatic process-associated protein(gene name synonym)|uniprotkb:Metastasis inhibition factor nm23(gene name synonym)|uniprotkb:Granzyme A-activated DNase(gene name synonym)|uniprotkb:NME1(gene name)|psi-mi:NME1(display_short)|uniprotkb:NDPKA(gene name synonym)|uniprotkb:NM23(gene name synonym)|uniprotkb:NM23-H1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11525820|imex:IM-24995-363	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	refseq:NP_000260.1|refseq:NP_937818.1|ensembl:ENSG00000239672(gene)|ensembl:ENST00000393196(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0002762"(negative regulation of myeloid leukocyte differentiation)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004536"(deoxyribonuclease activity)|go:"GO:0004550"(nucleoside diphosphate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0006183"(GTP biosynthetic process)|go:"GO:0006228"(UTP biosynthetic process)|go:"GO:0006241"(CTP biosynthetic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007595"(lactation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014075"(response to amine)|go:"GO:0016020"(membrane)|go:"GO:0019215"(intermediate filament binding)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051591"(response to cAMP)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071398"(cellular response to fatty acid)|interpro:IPR001564(Nucleoside diphosphate kinase, core)|go:"GO:0019899"(enzyme binding)|interpro:IPR023005|go:"GO:0021766"(hippocampus development)|interpro:IPR034907|interpro:IPR036850|mint:P15531|go:"GO:0030154"(cell differentiation)|go:"GO:0032587"(ruffle membrane)|rcsb pdb:1JXV|rcsb pdb:1UCN|go:"GO:0033574"(response to testosterone)|go:"GO:0035690"|rcsb pdb:2HVD|rcsb pdb:2HVE|rcsb pdb:3L7U|rcsb pdb:4ENO|rcsb pdb:5UI4|reactome:R-HSA-499943|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043024"(ribosomal small subunit binding)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|dip:DIP-39164N|entrezgene/locuslink:4830(identity)	-	crc64:A5409FAF1594854C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	rogid:Ut4gK1Xq786CaZzvqdS1eiU5op89606	intact-crc:1F7AB3020622253F|rigid:ApbTyx03y8NP4HEFMg5O/XwkyP8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P43365	uniprotkb:P32502	intact:EBI-749530|uniprotkb:Q9NSD3|intact:EBI-10178394|uniprotkb:Q6FHH8|ensembl:ENSP00000350592|ensembl:ENSP00000377447|ensembl:ENSP00000377478	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:magac_human(display_long)|uniprotkb:MAGE-12 antigen(gene name synonym)|uniprotkb:MAGE12F antigen(gene name synonym)|uniprotkb:Cancer/testis antigen 1.12(gene name synonym)|uniprotkb:MAGEA12(gene name)|psi-mi:MAGEA12(display_short)|uniprotkb:MAGE12(gene name synonym)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11525875|imex:IM-24995-369	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001159858.1|refseq:NP_001159859.1|refseq:NP_005358.2|ensembl:ENSG00000213401(gene)|ensembl:ENST00000357916(transcript)|ensembl:ENST00000393869(transcript)|ensembl:ENST00000393900(transcript)|interpro:IPR002190(MAGE protein)|interpro:IPR021072|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|entrezgene/locuslink:4111(identity)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	-	-	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:3/Jxz2VsFOb67RWqWj3xbTrw3s49606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:457ED85B533C84F6|rigid:6eAeGA0x7ECNoUuCK2qW0T7OZ8Y	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32502	uniprotkb:P35520	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	intact:EBI-740135|uniprotkb:Q99425|uniprotkb:Q9BWC5|uniprotkb:B2R993|uniprotkb:D3DSK4|intact:EBI-14245939|ensembl:ENSP00000344460|ensembl:ENSP00000352643|ensembl:ENSP00000381225|ensembl:ENSP00000381231	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:cbs_human(display_long)|uniprotkb:CBS(gene name)|psi-mi:CBS(display_short)|uniprotkb:Serine sulfhydrase(gene name synonym)|uniprotkb:Beta-thionase(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11525847|imex:IM-24995-366	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	refseq:NP_000062.1|refseq:NP_001171479.1|refseq:NP_001171480.1|ensembl:ENSG00000160200(gene)|ensembl:ENST00000352178(transcript)|ensembl:ENST00000359624(transcript)|ensembl:ENST00000398158(transcript)|go:"GO:0004122"(cystathionine beta-synthase activity)|ensembl:ENST00000398165(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006535"(cysteine biosynthetic process from serine)|go:"GO:0006563"(L-serine metabolic process)|go:"GO:0006565"(L-serine catabolic process)|go:"GO:0019343"(cysteine biosynthetic process via cystathionine)|go:"GO:0019344"(cysteine biosynthetic process)|go:"GO:0019346"(transsulfuration)|go:"GO:0019448"(L-cysteine catabolic process)|go:"GO:0019825"(oxygen binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0020037"(heme binding)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042262"(DNA protection)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043418"(homocysteine catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0050421"("nitrite reductase (NO-forming) activity")|go:"GO:0050667"(homocysteine metabolic process)|go:"GO:0070025"(carbon monoxide binding)|go:"GO:0070026"(nitric oxide binding)|go:"GO:0070814"(hydrogen sulfide biosynthetic process)|go:"GO:0072341"(modified amino acid binding)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR001216(Cysteine synthase/cystathionine beta-synthase P-phosphate-binding site)|interpro:IPR001926(Pyridoxal phosphate-dependent enzyme, beta subunit)|interpro:IPR005857(Cystathionine beta-synthase)|interpro:IPR036052|mint:P35520|rcsb pdb:1JBQ|rcsb pdb:1M54|rcsb pdb:4COO|rcsb pdb:4L0D|rcsb pdb:4L27|rcsb pdb:4L28|rcsb pdb:4L3V|rcsb pdb:4PCU|rcsb pdb:4UUU|rcsb pdb:5MMS|reactome:R-HSA-1614603|reactome:R-HSA-2408508|refseq:XP_011528079.1|refseq:XP_011528083.1|refseq:XP_011528084.1|refseq:XP_011544396.1|refseq:XP_011544397.1|refseq:XP_011544399.1|refseq:XP_011544400.1|refseq:XP_011544401.1|refseq:NP_001307227.1|refseq:NP_001308002.1|refseq:XP_016883700.1|refseq:XP_016883701.1|refseq:XP_016883702.1|refseq:XP_016883703.1|refseq:XP_016883704.1|refseq:XP_016883705.1|refseq:XP_016883706.1|refseq:XP_016883707.1|refseq:XP_016883978.1|refseq:XP_016883979.1|refseq:XP_016883980.1|refseq:XP_016883981.1|entrezgene/locuslink:875(identity)	-	crc64:A5409FAF1594854C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	rogid:f9eo0cPOHppVY7Nqejag3YyK18s9606	intact-crc:7212DC70771FDE67|rigid:ADANlPLz4St9Yu5ZB2FdFPX9NCA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38432	uniprotkb:P32502	intact:EBI-945751|uniprotkb:B2R931|ensembl:ENSP00000240316	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:coil_human(display_long)|uniprotkb:COIL(gene name)|psi-mi:COIL(display_short)|uniprotkb:CLN80(gene name synonym)|uniprotkb:p80-coilin(gene name synonym)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11525857|imex:IM-24995-367	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004636.1|dip:DIP-38503N|ensembl:ENSG00000121058(gene)|ensembl:ENST00000240316(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0015030"(Cajal body)|go:"GO:0016020"(membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0030619"(U1 snRNA binding)|go:"GO:0030620"(U2 snRNA binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR024822|interpro:IPR031722|mint:P38432|entrezgene/locuslink:8161(identity)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	-	-	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:hd5p6AbyA/GYNEeca99Mdb41qM09606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:6FEE11D039946565|rigid:xh14u3vqTThWSaUBxfd/0lTwQwA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32502	uniprotkb:P43356	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	intact:EBI-5650739|uniprotkb:A8K328|uniprotkb:Q32NC6|ensembl:ENSP00000333487|ensembl:ENSP00000359316|ensembl:ENSP00000469919|ensembl:ENSP00000470872|ensembl:ENSP00000480491|ensembl:ENSP00000480738|ensembl:ENSP00000484290|ensembl:ENSP00000485391|ensembl:ENSP00000485541|ensembl:ENSP00000507594|ensembl:ENSP00000507899	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:maga2_human(display_long)|uniprotkb:MAGEA2(gene name)|psi-mi:MAGEA2(display_short)|uniprotkb:MAGEA2B(gene name)|psi-mi:MAGEA2B(display_short)|uniprotkb:MAGE2(gene name synonym)|uniprotkb:MAGEA2A(gene name synonym)|uniprotkb:MAGE2(gene name synonym)|uniprotkb:MAGEA2(gene name synonym)|uniprotkb:Cancer/testis antigen 1.2(gene name synonym)|uniprotkb:MAGE-2 antigen(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11525866|imex:IM-24995-368	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	refseq:NP_001269430.1|refseq:NP_001269431.1|refseq:NP_001269433.1|refseq:NP_001269434.1|refseq:NP_001308329.1|refseq:NP_001308330.1|refseq:NP_001308331.1|refseq:NP_001308332.1|refseq:NP_001308333.1|refseq:NP_005352.1|refseq:NP_705692.1|refseq:NP_786884.1|refseq:NP_786885.1|dip:DIP-61231N|refseq:XP_016884895.1|refseq:XP_016885008.1|ensembl:ENSG00000183305(gene)|ensembl:ENSG00000268606(gene)|ensembl:ENST00000331220(transcript)|ensembl:ENST00000370293(transcript)|ensembl:ENST00000595583(transcript)|ensembl:ENST00000598543(transcript)|ensembl:ENST00000611557(transcript)|ensembl:ENST00000611674(transcript)|ensembl:ENST00000620710(transcript)|ensembl:ENST00000623438(transcript)|ensembl:ENST00000623806(transcript)|ensembl:ENST00000682532(transcript)|ensembl:ENST00000684311(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0016605"(PML body)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0033234"(negative regulation of protein sumoylation)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0044257"(cellular protein catabolic process)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0072331"(signal transduction by p53 class mediator)|go:"GO:0090398"(cellular senescence)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901984"(negative regulation of protein acetylation)|interpro:IPR002190(MAGE protein)|interpro:IPR021072|interpro:IPR030103|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|entrezgene/locuslink:266740(identity)	-	crc64:A5409FAF1594854C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	rogid:aYv4+irEk9vGE2f3yZQR8hCQGec9606	intact-crc:6C8866246637F3BE|rigid:4uhle33EU3ueWB3NIALf2R+j2dM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P55212	uniprotkb:P32502	intact:EBI-718729|uniprotkb:Q9BQE7|ensembl:ENSP00000265164	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:casp6_human(display_long)|uniprotkb:Apoptotic protease Mch-2(gene name synonym)|uniprotkb:CASP6(gene name)|psi-mi:CASP6(display_short)|uniprotkb:MCH2(gene name synonym)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11525904|imex:IM-24995-372	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001217.2|refseq:NP_116787.1|rcsb pdb:3K7E|rcsb pdb:3NKF|rcsb pdb:3NR2|rcsb pdb:3OD5|rcsb pdb:3P45|rcsb pdb:3P4U|rcsb pdb:3QNW|rcsb pdb:3S70|rcsb pdb:3S8E|rcsb pdb:3V6L|rcsb pdb:3V6M|rcsb pdb:4EJF|rcsb pdb:4FXO|rcsb pdb:4HVA|rcsb pdb:4IYR|rcsb pdb:4N5D|rcsb pdb:4N6G|rcsb pdb:4N7J|rcsb pdb:4N7M|rcsb pdb:4NBK|rcsb pdb:4NBL|rcsb pdb:4NBN|rcsb pdb:6DEU|rcsb pdb:6DEV|reactome:R-HSA-111465|reactome:R-HSA-264870|reactome:R-HSA-352238|reactome:R-HSA-6803207|ensembl:ENSG00000138794(gene)|ensembl:ENST00000265164(transcript)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006508"(proteolysis)|go:"GO:0006915"(apoptotic process)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0072734"(cellular response to staurosporine)|go:"GO:0097153"(cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0097200"(cysteine-type endopeptidase activity involved in execution phase of apoptosis)|interpro:IPR001309(Peptidase C14, ICE, catalytic subunit p20)|interpro:IPR002138(Peptidase C14, caspase non-catalytic subunit p10)|interpro:IPR002398(Peptidase C14, caspase precursor p45)|interpro:IPR015917(Peptidase C14, caspase precursor p45, core)|interpro:IPR016129(Peptidase C14, ICE, catalytic subunit p20, active site)|interpro:IPR029030|interpro:IPR033139|interpro:IPR037554|mint:P55212|rcsb pdb:1MI9|rcsb pdb:2WDP|dip:DIP-44649N|entrezgene/locuslink:839(identity)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	-	-	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:x335dTT6omZBrEGs7jzxOjUWaNM9606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:C2F0C7E3F9F56CB7|rigid:dfY8xgiMbt4rskxNsX0THjbpt1I	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48775	uniprotkb:P32502	intact:EBI-743494|ensembl:ENSP00000444788|ensembl:ENSP00000460086|uniprotkb:A8K053	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:t23o_human(display_long)|uniprotkb:Tryptophan pyrrolase(gene name synonym)|uniprotkb:Tryptophan oxygenase(gene name synonym)|uniprotkb:Tryptamin 2,3-dioxygenase(gene name synonym)|uniprotkb:TDO2(gene name)|psi-mi:TDO2(display_short)|uniprotkb:TDO(gene name synonym)|uniprotkb:Tryptophanase(gene name synonym)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11525884|imex:IM-24995-370	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000151790(gene)|ensembl:ENSG00000262635(gene)|ensembl:ENST00000536354(transcript)|ensembl:ENST00000573403(transcript)|go:"GO:0004833"(tryptophan 2,3-dioxygenase activity)|go:"GO:0005829"(cytosol)|go:"GO:0016597"(amino acid binding)|go:"GO:0019441"(tryptophan catabolic process to kynurenine)|go:"GO:0019442"(tryptophan catabolic process to acetyl-CoA)|go:"GO:0019825"(oxygen binding)|go:"GO:0020037"(heme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051289"(protein homotetramerization)|go:"GO:1904842"(response to nitroglycerin)|interpro:IPR004981(Tryptophan 2,3-dioxygenase)|interpro:IPR037217|mint:P48775|rcsb pdb:4PW8|rcsb pdb:5TI9|rcsb pdb:5TIA|rcsb pdb:6A4I|rcsb pdb:6PYY|rcsb pdb:6PYZ|rcsb pdb:6UD5|rcsb pdb:6VBN|reactome:R-HSA-71240|refseq:NP_005642.1|entrezgene/locuslink:6999(identity)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	-	-	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:S+cyc710I52nIFQWgKhXFul9QZw9606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:D8D8861D74716789|rigid:ppffcJhnWTZPhNOu91xniZ0FcvE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32502	uniprotkb:P49247	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	intact:EBI-744831|uniprotkb:Q541P9|uniprotkb:Q96BJ6|ensembl:ENSP00000283646	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:rpia_human(display_long)|uniprotkb:Phosphoriboisomerase(gene name synonym)|uniprotkb:RPIA(gene name)|psi-mi:RPIA(display_short)|uniprotkb:RPI(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11525893|imex:IM-24995-371	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	refseq:NP_653164.2|ensembl:ENSG00000153574(gene)|ensembl:ENST00000283646(transcript)|go:"GO:0004751"(ribose-5-phosphate isomerase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006014"(D-ribose metabolic process)|go:"GO:0006098"(pentose-phosphate shunt)|go:"GO:0009052"(pentose-phosphate shunt, non-oxidative branch)|go:"GO:0019693"(ribose phosphate metabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048029"(monosaccharide binding)|interpro:IPR004788(Ribose 5-phosphate isomerase)|interpro:IPR020672|interpro:IPR037171|mint:P49247|reactome:R-HSA-5659996|reactome:R-HSA-6791461|reactome:R-HSA-71336|entrezgene/locuslink:22934(identity)	-	crc64:A5409FAF1594854C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	rogid:gddu0Xp/dx4JwbFMs50pQCvvbws9606	intact-crc:5BF75D6E0DC25883|rigid:FIQgDE5w8ZRTYm40k7VpBlc0dhA	false	-	sufficient binding region:75-311	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P98170	uniprotkb:P32502	intact:EBI-517127|uniprotkb:Q9NQ14|uniprotkb:D3DTF2|ensembl:ENSP00000347858|ensembl:ENSP00000360242|ensembl:ENSP00000395230	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:xiap_human(display_long)|uniprotkb:Inhibitor of apoptosis protein 3(gene name synonym)|uniprotkb:X-linked inhibitor of apoptosis protein(gene name synonym)|uniprotkb:IAP-like protein(gene name synonym)|uniprotkb:XIAP(gene name)|psi-mi:XIAP(display_short)|uniprotkb:API3(gene name synonym)|uniprotkb:IAP3(gene name synonym)|uniprotkb:BIRC4(gene name synonym)|uniprotkb:Baculoviral IAP repeat-containing protein 4(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase XIAP(gene name synonym)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11525949|imex:IM-24995-377	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006724817.1|refseq:NP_001158.2|refseq:NP_001191330.1|refseq:XP_011529631.1|dip:DIP-27626N|ensembl:ENSG00000101966(gene)|ensembl:ENST00000355640(transcript)|ensembl:ENST00000371199(transcript)|ensembl:ENST00000434753(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005876"(spindle microtubule)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030510"(regulation of BMP signaling pathway)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0055070"(copper ion homeostasis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070424"(regulation of nucleotide-binding oligomerization domain containing signaling pathway)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:1902530"(positive regulation of protein linear polyubiquitination)|go:"GO:1990001"(inhibition of cysteine-type endopeptidase activity involved in apoptotic process)|interpro:IPR001370(Proteinase inhibitor I32, inhibitor of apoptosis)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011029(DEATH-like)|interpro:IPR042579|mint:P98170|rcsb pdb:1C9Q|rcsb pdb:1F9X|rcsb pdb:1G3F|rcsb pdb:1G73|rcsb pdb:1I3O|rcsb pdb:1I4O|rcsb pdb:1I51|rcsb pdb:1KMC|rcsb pdb:1NW9|rcsb pdb:1TFQ|rcsb pdb:1TFT|rcsb pdb:2ECG|rcsb pdb:2JK7|rcsb pdb:2KNA|rcsb pdb:2OPY|rcsb pdb:2OPZ|rcsb pdb:2POI|rcsb pdb:2POP|rcsb pdb:2QRA|rcsb pdb:2VSL|rcsb pdb:3CLX|rcsb pdb:3CM2|rcsb pdb:3CM7|rcsb pdb:3EYL|rcsb pdb:3G76|rcsb pdb:3HL5|rcsb pdb:3UW4|rcsb pdb:3UW5|rcsb pdb:4EC4|rcsb pdb:4HY0|rcsb pdb:4IC2|rcsb pdb:4IC3|rcsb pdb:4J3Y|rcsb pdb:4J44|rcsb pdb:4J45|rcsb pdb:4J46|rcsb pdb:4J47|rcsb pdb:4J48|rcsb pdb:4KJU|rcsb pdb:4KJV|rcsb pdb:4KMP|rcsb pdb:4MTZ|rcsb pdb:4OXC|rcsb pdb:4WVS|rcsb pdb:4WVT|rcsb pdb:4WVU|rcsb pdb:5C0K|rcsb pdb:5C0L|rcsb pdb:5C3H|rcsb pdb:5C3K|rcsb pdb:5C7A|rcsb pdb:5C7B|rcsb pdb:5C7C|rcsb pdb:5C7D|rcsb pdb:5C83|rcsb pdb:5C84|rcsb pdb:5M6E|rcsb pdb:5M6F|rcsb pdb:5M6H|rcsb pdb:5M6L|rcsb pdb:5M6M|rcsb pdb:5O6T|rcsb pdb:5OQW|rcsb pdb:6EY2|rcsb pdb:6GJW|rcsb pdb:6QCI|reactome:R-HSA-111459|reactome:R-HSA-111463|reactome:R-HSA-111464|reactome:R-HSA-111469|reactome:R-HSA-3769402|reactome:R-HSA-5213460|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5675482|reactome:R-HSA-8948747|reactome:R-HSA-8948751|reactome:R-HSA-9627069|entrezgene/locuslink:331(identity)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	-	-	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:6eDcOay+c2ZmIAD/pwnCDROBwgM9606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:E1C25372ED53E4FC|rigid:LhvS0Fwa9VQ4GHPRulcrwvJqPig	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32502	uniprotkb:P63279	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11525940|imex:IM-24995-376	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N|entrezgene/locuslink:7329(identity)	-	crc64:A5409FAF1594854C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	intact-crc:D992B2A617C05BB0|rigid:J5OBNYvMFV2v9zhlut1DhG67OVg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P56279	uniprotkb:P32502	intact:EBI-749995|uniprotkb:Q6IBK7|ensembl:ENSP00000385036|ensembl:ENSP00000450496|ensembl:ENSP00000450701|ensembl:ENSP00000451506	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:tcl1a_human(display_long)|uniprotkb:Protein p14 TCL1(gene name synonym)|uniprotkb:Oncogene TCL-1(gene name synonym)|uniprotkb:TCL1A(gene name)|psi-mi:TCL1A(display_short)|uniprotkb:TCL1(gene name synonym)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11525913|imex:IM-24995-373	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001092195.1|refseq:NP_068801.1|refseq:XP_016877165.1|refseq:XP_016877166.1|dip:DIP-60787N|ensembl:ENSG00000100721(gene)|ensembl:ENST00000402399(transcript)|ensembl:ENST00000554012(transcript)|ensembl:ENST00000555202(transcript)|ensembl:ENST00000556450(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010918"(positive regulation of mitochondrial membrane potential)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|interpro:IPR004832(TCL1/MTCP1)|interpro:IPR036672|rcsb pdb:1JSG|entrezgene/locuslink:8115(identity)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	-	-	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:c3GIYkYNb+wWlxn59oU2vpvbfhI9606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:19DC0C33E6793C84|rigid:CIW6CN8FzBdRzFyhwkSFg435ROc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P61289	uniprotkb:P32502	intact:EBI-355546|uniprotkb:O35563|uniprotkb:P97373|uniprotkb:Q12920|uniprotkb:Q13172|uniprotkb:Q9BQD9|uniprotkb:A8K9A3|ensembl:ENSP00000466794	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:psme3_human(display_long)|uniprotkb:PSME3(gene name)|psi-mi:PSME3(display_short)|uniprotkb:Proteasome activator 28 subunit gamma(gene name synonym)|uniprotkb:Activator of multicatalytic protease subunit 3(gene name synonym)|uniprotkb:11S regulator complex subunit gamma(gene name synonym)|uniprotkb:Ki nuclear autoantigen(gene name synonym)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11525922|imex:IM-24995-374	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005780.2|refseq:NP_789839.1|ensembl:ENSG00000131467(gene)|ensembl:ENST00000590720(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0008537"(proteasome activator complex)|go:"GO:0010950"(positive regulation of endopeptidase activity)|go:"GO:0016020"(membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0061133"(endopeptidase activator activity)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0097371"(MDM2/MDM4 family protein binding)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR003185(Proteasome activator pa28, REG alpha subunit)|interpro:IPR003186(Proteasome activator pa28, REG beta subunit)|interpro:IPR009077(Proteasome activator pa28, REG alpha/beta subunit)|interpro:IPR036252|interpro:IPR036996|interpro:IPR036997|mint:P61289|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|entrezgene/locuslink:10197(identity)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	-	-	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:6EQY2Kj3Juf++m4eBDzPWMgbC2k9606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:66B21C9DB54D0154|rigid:QW7H1v5iA2hK7wS1iphn9qRlhQg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32502	uniprotkb:P61457	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	intact:EBI-740475|ensembl:ENSP00000299299|uniprotkb:P70519|uniprotkb:P80095|uniprotkb:Q9D930	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:phs_human(display_long)|uniprotkb:4-alpha-hydroxy-tetrahydropterin dehydratase(gene name synonym)|uniprotkb:Phenylalanine hydroxylase-stimulating protein(gene name synonym)|uniprotkb:Pterin carbinolamine dehydratase(gene name synonym)|uniprotkb:Dimerization cofactor of hepatocyte nuclear factor 1-alpha(gene name synonym)|uniprotkb:PCBD1(gene name)|psi-mi:PCBD1(display_short)|uniprotkb:DCOH(gene name synonym)|uniprotkb:PCBD(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11525931|imex:IM-24995-375	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	refseq:NP_000272.1|ensembl:ENSG00000166228(gene)|ensembl:ENST00000299299(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004505"(phenylalanine 4-monooxygenase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006558"(L-phenylalanine metabolic process)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0008124"(4-alpha-hydroxytetrahydrobiopterin dehydratase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001533(Transcriptional coactivator/pterin dehydratase)|interpro:IPR036428|mint:P61457|reactome:R-HSA-8964208|refseq:NP_001276726.1|entrezgene/locuslink:5092(identity)	-	crc64:A5409FAF1594854C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	rogid:WsAu8slwInyWOA2p/z+JqTvyKP49606	intact-crc:303B3DEF1E771F08|rigid:ws63suhiisK0D+qYFpMFXmdE6YY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q13155	uniprotkb:P32502	intact:EBI-745226|uniprotkb:Q75MR1|uniprotkb:Q96CZ5|uniprotkb:Q9P1L2|ensembl:ENSP00000223029|uniprotkb:F8W950	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:aimp2_human(display_long)|uniprotkb:Protein JTV-1(gene name synonym)|uniprotkb:AIMP2(gene name)|psi-mi:AIMP2(display_short)|uniprotkb:PRO0992(orf name)|uniprotkb:JTV1(gene name synonym)|uniprotkb:Multisynthase complex auxiliary component p38(gene name synonym)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11525986|imex:IM-24995-381	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006294.2|ensembl:ENSG00000106305(gene)|ensembl:ENST00000223029(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0006915"(apoptotic process)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0017101"(aminoacyl-tRNA synthetase multienzyme complex)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060510"(type II pneumocyte differentiation)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1903632"(positive regulation of aminoacyl-tRNA ligase activity)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR031889|interpro:IPR036282|interpro:IPR041503|interpro:IPR042360|mint:Q13155|rcsb pdb:4DPG|rcsb pdb:4YCU|rcsb pdb:4YCW|rcsb pdb:5A1N|rcsb pdb:5A34|rcsb pdb:5A5H|rcsb pdb:5Y6L|rcsb pdb:6ILD|rcsb pdb:6IY6|rcsb pdb:6JPV|rcsb pdb:6K39|reactome:R-HSA-2408522|reactome:R-HSA-379716|dip:DIP-34421N|refseq:NP_001313536.1|entrezgene/locuslink:7965(identity)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	-	-	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:VEBmJjo6t3dBY6mKpmUyVLamJFQ9606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:13CEDF4915EF2E89|rigid:F3XDrjB1HkR0VvZZQGaFt+lZ3b0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32502	uniprotkb:Q00796	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	intact:EBI-750068|uniprotkb:B2R655|uniprotkb:Q16682|uniprotkb:Q9UMD6|uniprotkb:B7Z3A6|uniprotkb:J3JZZ5|ensembl:ENSP00000267814	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:dhso_human(display_long)|uniprotkb:L-iditol 2-dehydrogenase(gene name synonym)|uniprotkb:SORD(gene name)|psi-mi:SORD(display_short)|uniprotkb:"(R,R)-butanediol dehydrogenase"(gene name synonym)|uniprotkb:Polyol dehydrogenase(gene name synonym)|uniprotkb:Ribitol dehydrogenase(gene name synonym)|uniprotkb:Xylitol dehydrogenase(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11525958|imex:IM-24995-378	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	refseq:NP_003095.2|ensembl:ENSG00000140263(gene)|ensembl:ENST00000267814(transcript)|go:"GO:0000721"("(R,R)-butanediol dehydrogenase activity")|go:"GO:0003939"(L-iditol 2-dehydrogenase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006062"(sorbitol catabolic process)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009725"(response to hormone)|go:"GO:0016020"(membrane)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0031514"(motile cilium)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0046370"(fructose biosynthetic process)|go:"GO:0046526"(D-xylulose reductase activity)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0046688"(response to copper ion)|go:"GO:0050255"(ribitol 2-dehydrogenase activity)|go:"GO:0051160"(L-xylitol catabolic process)|go:"GO:0051164"(L-xylitol metabolic process)|go:"GO:0051287"(NAD binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002328(Alcohol dehydrogenase, zinc-containing, conserved site)|interpro:IPR011032(GroES-like)|interpro:IPR013149(Alcohol dehydrogenase, zinc-binding)|interpro:IPR013154(Alcohol dehydrogenase GroES-like)|interpro:IPR020843|interpro:IPR036291|mint:Q00796|rcsb pdb:1PL6|rcsb pdb:1PL7|rcsb pdb:1PL8|reactome:R-HSA-5652227|reactome:R-HSA-5661270|entrezgene/locuslink:6652(identity)	-	crc64:A5409FAF1594854C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	rogid:BGqvXy2I7nmCLPYTOkUcQ8fpCkk9606	intact-crc:F63D7A46771F1183|rigid:WUFHFrW4kPfzg2PwNlplkSvfOcI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q03393	uniprotkb:P32502	intact:EBI-712344|ensembl:ENSP00000280362|uniprotkb:Q8WVG8|uniprotkb:B0YJ87	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:ptps_human(display_long)|uniprotkb:PTS(gene name)|psi-mi:PTS(display_short)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11525967|imex:IM-24995-379	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000308.1|ensembl:ENSG00000150787(gene)|ensembl:ENST00000280362(transcript)|go:"GO:0003874"(6-pyruvoyltetrahydropterin synthase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006520"(cellular amino acid metabolic process)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0007417"(central nervous system development)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR007115(6-pyruvoyl tetrahydropterin synthase-related)|interpro:IPR022469|interpro:IPR022470|interpro:IPR038418|rcsb pdb:3I2B|reactome:R-HSA-1474151|entrezgene/locuslink:5805(identity)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	-	-	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Qa3bMpzyvRxrvDq9dZUSQlfbpeg9606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:6F27AE61C6CB4528|rigid:yR/xKlV7hNDD/Q9EM8NqkgdEspw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q13049	uniprotkb:P32502	intact:EBI-742790|ensembl:ENSP00000363095|ensembl:ENSP00000408292|uniprotkb:Q9NQP8	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:tri32_human(display_long)|uniprotkb:Zinc finger protein HT2A(gene name synonym)|uniprotkb:72 kDa Tat-interacting protein(gene name synonym)|uniprotkb:TRIM32(gene name)|psi-mi:TRIM32(display_short)|uniprotkb:HT2A(gene name synonym)|uniprotkb:Tripartite motif-containing protein 32(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM32(gene name synonym)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11525977|imex:IM-24995-380	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0043621"(protein self-association)|go:"GO:0045087"(innate immune response)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051155"(positive regulation of striated muscle cell differentiation)|go:"GO:0061564"(axon development)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1902187"|go:"GO:1902230"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:1903265"(positive regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:1903883"(positive regulation of interleukin-17-mediated signaling pathway)|go:"GO:1903886"("positive regulation of chemokine (C-C motif) ligand 20 production")|go:"GO:2000147"(positive regulation of cell motility)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENSG00000119401(gene)|ensembl:ENST00000373983(transcript)|ensembl:ENST00000450136(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001894"(tissue homeostasis)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005863"(striated muscle myosin thick filament)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007014"(actin ubiquitination)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009411"(response to UV)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0017022"(myosin binding)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030957"(Tat protein binding)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034612"(response to tumor necrosis factor)|go:"GO:0042802"(identical protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|interpro:IPR000315(Zinc finger, B-box)|refseq:NP_001093149.1|refseq:XP_011516700.1|refseq:NP_036342.2|refseq:XP_005251870.1|interpro:IPR001258(NHL repeat)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR013017(NHL repeat, subgroup)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR027370|mint:Q13049|rcsb pdb:2CT2|rcsb pdb:5FEY|reactome:R-HSA-3134975|reactome:R-HSA-983168|refseq:XP_016869975.1|entrezgene/locuslink:22954(identity)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	-	-	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:XuqprQd10kSpsuyGs+FSdzIdJ/Y9606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:FEC6284DE62B0F82|rigid:rHcMBkLR5Rdd3LnDcpJZingk8vU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32502	uniprotkb:Q53EZ4	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	intact:EBI-747776|uniprotkb:Q32WF5|uniprotkb:Q3MV20|uniprotkb:Q5VY28|uniprotkb:Q6N034|ensembl:ENSP00000360540|uniprotkb:Q96H32|uniprotkb:Q9NVS7|uniprotkb:B2RDG8|intact:EBI-10173536|uniprotkb:D3DR37|intact:EBI-28973801	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:cep55_human(display_long)|uniprotkb:Up-regulated in colon cancer 6(gene name synonym)|uniprotkb:CEP55(gene name)|psi-mi:CEP55(display_short)|uniprotkb:URCC6(gene name synonym)|uniprotkb:C10orf3(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11526023|imex:IM-24995-385	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	refseq:NP_001120654.1|refseq:NP_060601.3|ensembl:ENSG00000138180(gene)|ensembl:ENST00000371485(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0014066"(regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0030496"(midbody)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042802"(identical protein binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0061952"(midbody abscission)|go:"GO:0090543"(Flemming body)|go:"GO:1904888"(cranial skeletal system development)|interpro:IPR022008|interpro:IPR038926|mint:Q53EZ4|rcsb pdb:3E1R|rcsb pdb:3WUT|rcsb pdb:3WUU|rcsb pdb:3WUV|go:"GO:0005814"(centriole)|ensembl:ENSP00000360540|dip:DIP-44581N|entrezgene/locuslink:55165(identity)	-	crc64:A5409FAF1594854C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	rogid:tuo36vVb8ZgPDR81YjZFNEg559w9606	intact-crc:2A2347A7D83D3284|rigid:2kHflvspg2fhw+Zk3atP8GZBmTk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32502	uniprotkb:Q13490	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	intact:EBI-514538|uniprotkb:Q16516|uniprotkb:Q4TTG0|uniprotkb:B4E026|ensembl:ENSP00000227758|ensembl:ENSP00000477613	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:birc2_human(display_long)|uniprotkb:Inhibitor of apoptosis protein 2(gene name synonym)|uniprotkb:TNFR2-TRAF-signaling complex protein 2(gene name synonym)|uniprotkb:IAP homolog B(gene name synonym)|uniprotkb:RING finger protein 48(gene name synonym)|uniprotkb:BIRC2(gene name)|psi-mi:BIRC2(display_short)|uniprotkb:API1(gene name synonym)|uniprotkb:MIHB(gene name synonym)|uniprotkb:RNF48(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase BIRC2(gene name synonym)|uniprotkb:Cellular inhibitor of apoptosis 1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11525996|imex:IM-24995-382	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	refseq:NP_001157.1|refseq:NP_001243095.1|refseq:NP_001243092.1|dip:DIP-33485N|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0045471"(response to ethanol)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051087"(chaperone binding)|go:"GO:0051591"(response to cAMP)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060544"(regulation of necroptotic process)|go:"GO:0060546"(negative regulation of necroptotic process)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070266"(necroptotic process)|go:"GO:0070424"(regulation of nucleotide-binding oligomerization domain containing signaling pathway)|go:"GO:0098770"(FBXO family protein binding)|go:"GO:1901222"(regulation of NIK/NF-kappaB signaling)|go:"GO:1902443"(negative regulation of ripoptosome assembly involved in necroptotic process)|go:"GO:1902523"(positive regulation of protein K63-linked ubiquitination)|go:"GO:1902524"(positive regulation of protein K48-linked ubiquitination)|go:"GO:1902527"(positive regulation of protein monoubiquitination)|go:"GO:2000116"(regulation of cysteine-type endopeptidase activity)|go:"GO:2000377"(regulation of reactive oxygen species metabolic process)|interpro:IPR001315(Caspase Recruitment)|interpro:IPR001370(Proteinase inhibitor I32, inhibitor of apoptosis)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011029(DEATH-like)|interpro:IPR041933|mint:Q13490|rcsb pdb:1QBH|rcsb pdb:2L9M|rcsb pdb:3D9T|rcsb pdb:3D9U|rcsb pdb:3M1D|rcsb pdb:3MUP|rcsb pdb:3OZ1|rcsb pdb:3T6P|rcsb pdb:3UW4|rcsb pdb:4EB9|rcsb pdb:4HY4|rcsb pdb:4HY5|rcsb pdb:4KMN|rcsb pdb:4LGE|rcsb pdb:4LGU|rcsb pdb:4MTI|rcsb pdb:4MU7|rcsb pdb:5M6N|rcsb pdb:6EXW|rcsb pdb:6HPR|rcsb pdb:6W74|rcsb pdb:6W7O|rcsb pdb:6W8I|reactome:R-HSA-111465|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-5213460|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5668541|reactome:R-HSA-5675482|reactome:R-HSA-5676594|reactome:R-HSA-5689880|reactome:R-HSA-937041|ensembl:ENSG00000110330(gene)|ensembl:ENST00000227758(transcript)|ensembl:ENST00000613397(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001741"(XY body)|go:"GO:0001890"(placenta development)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0016740"(transferase activity)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034121"(regulation of toll-like receptor signaling pathway)|go:"GO:0035631"(CD40 receptor complex)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0039535"(regulation of RIG-I signaling pathway)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|entrezgene/locuslink:329(identity)	-	crc64:A5409FAF1594854C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	rogid:FOikzyDyDtlv2l69i/WNDNq674A9606	intact-crc:638E3626E69660B4|rigid:OzX/AG4aATDjYDYDEi8FO1Y3P2g	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32502	uniprotkb:Q13554-3	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	intact:EBI-11523526|ensembl:ENSP00000351542	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:q13554-3(display_long)|uniprotkb:CAMK2B(gene name)|psi-mi:CAMK2B(display_short)|uniprotkb:CAM2(gene name synonym)|uniprotkb:CAMK2(gene name synonym)|uniprotkb:CAMKB(gene name synonym)|uniprotkb:Beta'E(isoform synonym)|uniprotkb:Beta1(isoform synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11526005|imex:IM-24995-383	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	ensembl:ENSG00000058404(gene)|ensembl:ENST00000358707(transcript)|intact:EBI-1058722(isoform-parent)|uniprotkb:Q13554-3(isoform-parent)|entrezgene/locuslink:816(identity)	-	crc64:A5409FAF1594854C	isoform-comment:"Ref.1 (AAD42036) sequence is in conflict in position: 316:A->V."	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	rogid:H/SPSRbW/NRcHPJs7Z2y6ESTrhM9606	intact-crc:E8810E301E2DEC8B|rigid:DKdWSpVJL+VPJ6ZusJRxw/O5DJ4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q14749	uniprotkb:P32502	intact:EBI-744239|uniprotkb:Q9NNZ1|uniprotkb:Q9NS24|uniprotkb:Q5T8W2|ensembl:ENSP00000361894	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:gnmt_human(display_long)|uniprotkb:GNMT(gene name)|psi-mi:GNMT(display_short)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11526014|imex:IM-24995-384	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_061833.1|refseq:NP_001305794.1|ensembl:ENSG00000124713(gene)|ensembl:ENST00000372808(transcript)|go:"GO:0005542"(folic acid binding)|go:"GO:0005829"(cytosol)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0006111"(regulation of gluconeogenesis)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006555"(methionine metabolic process)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0016594"(glycine binding)|go:"GO:0017174"(glycine N-methyltransferase activity)|go:"GO:0032259"(methylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0046498"(S-adenosylhomocysteine metabolic process)|go:"GO:0046500"(S-adenosylmethionine metabolic process)|go:"GO:0051289"(protein homotetramerization)|go:"GO:1901052"(sarcosine metabolic process)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|interpro:IPR014369(Glycine N-methyltransferase)|interpro:IPR029063|interpro:IPR041698|rcsb pdb:1R74|rcsb pdb:2AZT|reactome:R-HSA-2408508|reactome:R-HSA-389661|entrezgene/locuslink:27232(identity)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	-	-	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:noj0nCgjJ1Dq079ycrwAu30a4AU9606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:DFD88E804B54A710|rigid:8x0vbouDfpgFXpuOOybPIvyDrhI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32502	uniprotkb:Q5VSY0	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	intact:EBI-743722|uniprotkb:Q9BYI2|uniprotkb:Q96LI0|uniprotkb:Q9BYI1|uniprotkb:Q9H225|ensembl:ENSP00000365550	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:gkap1_human(display_long)|uniprotkb:GKAP42(gene name synonym)|uniprotkb:cGMP-dependent protein kinase-anchoring protein of 42 kDa(gene name synonym)|uniprotkb:FKSG21(orf name)|uniprotkb:GKAP1(gene name)|psi-mi:GKAP1(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11526059|imex:IM-24995-389	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	ensembl:ENSG00000165113(gene)|refseq:NP_001129425.1|refseq:NP_079487.2|refseq:XP_011517360.1|refseq:XP_005252298.1|ensembl:ENST00000376371(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0007165"(signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|interpro:IPR026109|dip:DIP-47324N|entrezgene/locuslink:80318(identity)	-	crc64:A5409FAF1594854C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	rogid:WPAqDDTftv300tbwXkusTo6tmUo9606	intact-crc:07FFDD2B01A32B73|rigid:CoAQLd/ljLQV7hG1azX99tfKnaI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32502	uniprotkb:Q53G59	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	intact:EBI-740929|ensembl:ENSP00000356230|uniprotkb:A6NEN8|uniprotkb:B7Z7B8|uniprotkb:Q9HBX5	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:klh12_human(display_long)|uniprotkb:CUL3-interacting protein 1(gene name synonym)|uniprotkb:KLHL12(gene name)|psi-mi:KLHL12(display_short)|uniprotkb:C3IP1(gene name synonym)|uniprotkb:DKIR homolog(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11526032|imex:IM-24995-386	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048208"(COPII vesicle coating)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR017096(Kelch-like protein, gigaxonin)|mint:Q53G59|rcsb pdb:2VPJ|rcsb pdb:6TTK|rcsb pdb:6V7O|reactome:R-HSA-4641258|refseq:NP_067646.1|ensembl:ENSG00000117153(gene)|ensembl:ENST00000367261(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0014029"(neural crest formation)|go:"GO:0014032"(neural crest cell development)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0034451"(centriolar satellite)|refseq:NP_001289980.1|refseq:NP_001290038.1|entrezgene/locuslink:59349(identity)	-	crc64:A5409FAF1594854C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	rogid:C4I/Ys9vqNqfG61HsXRZhywP4vE9606	intact-crc:64BCB2AE06F88795|rigid:QkZKqnQnfaRcRbHr7Uib0bBlOJ8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32502	uniprotkb:Q5JR59-3	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	intact:EBI-11522433|ensembl:ENSP00000370186	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:q5jr59-3(display_long)|uniprotkb:MTUS2(gene name)|psi-mi:MTUS2(display_short)|uniprotkb:CAZIP(gene name synonym)|uniprotkb:Cardiac zipper protein(gene name synonym)|uniprotkb:KIAA0774(gene name synonym)|uniprotkb:Microtubule plus-end tracking protein TIP150(gene name synonym)|uniprotkb:TIP150(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11526041|imex:IM-24995-387	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	ensembl:ENSG00000132938(gene)|ensembl:ENST00000380808(transcript)|intact:EBI-742948(isoform-parent)|uniprotkb:Q5JR59-3(isoform-parent)|entrezgene/locuslink:23281(identity)	-	crc64:A5409FAF1594854C	isoform-comment:No experimental confirmation available.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	rogid:npId9tC7VoLN/jteoBiRbSYChPs9606	intact-crc:2F0F9389936582DA|rigid:TOLzTALWlWRNyacE8+VOm+bAeFA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32502	uniprotkb:Q5T124-6	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	intact:EBI-11524408	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:q5t124-6(display_long)|uniprotkb:UBXN11(gene name)|psi-mi:UBXN11(display_short)|uniprotkb:Colorectal tumor-associated antigen COA-1(gene name synonym)|uniprotkb:SOC(gene name synonym)|uniprotkb:Socius(gene name synonym)|uniprotkb:UBX domain-containing protein 5(gene name synonym)|uniprotkb:UBXD5(gene name synonym)|uniprotkb:PP2243(orf name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11526050|imex:IM-24995-388	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	intact:EBI-746004(isoform-parent)|uniprotkb:Q5T124-6(isoform-parent)|entrezgene/locuslink:91544(identity)	-	crc64:A5409FAF1594854C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	rogid:1YSjG/p2ihcjl4P8KdPCaX2HxiY9606	intact-crc:04A20F794B056EAB|rigid:TCELETJrv2CLPOCOuIEVqKThbSA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q86WT6-2	uniprotkb:P32502	intact:EBI-11525489|ensembl:ENSP00000342922|ensembl:ENSP00000479720	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:q86wt6-2(display_long)|uniprotkb:RING-type E3 ubiquitin transferase TRIM69(gene name synonym)|uniprotkb:TRIM69(gene name)|psi-mi:TRIM69(display_short)|uniprotkb:RFP-like domain-containing protein trimless(gene name synonym)|uniprotkb:RING finger protein 36(gene name synonym)|uniprotkb:RNF36(gene name synonym)|uniprotkb:Tripartite motif-containing protein 69(gene name synonym)|uniprotkb:HSD-34(orf name)|uniprotkb:HSD34(orf name)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11526068|imex:IM-24995-390	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-749955(isoform-parent)|uniprotkb:Q86WT6-2(isoform-parent)|ensembl:ENSG00000185880(gene)|ensembl:ENSG00000278211(gene)|ensembl:ENST00000338264(transcript)|ensembl:ENST00000618398(transcript)|entrezgene/locuslink:140691(identity)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	-	-	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:J0mzn4PSX5vWZqt4X3Ee1Wxx5hw9606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:082FBDE8F619E22E|rigid:LgqfhMLw94zWouczTI/WdTVZE4c	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32502	uniprotkb:Q8IUQ4-2	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	intact:EBI-11522811|ensembl:ENSP00000349156	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:q8iuq4-2(display_long)|uniprotkb:SIAH1(gene name)|psi-mi:SIAH1(display_short)|uniprotkb:HUMSIAH(gene name synonym)|uniprotkb:Seven in absentia homolog 1(gene name synonym)|uniprotkb:Siah-1a(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase SIAH1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11526077|imex:IM-24995-391	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	intact:EBI-747107(isoform-parent)|ensembl:ENSG00000196470(gene)|ensembl:ENST00000356721(transcript)|uniprotkb:Q8IUQ4-2(isoform-parent)|entrezgene/locuslink:6477(identity)	-	crc64:A5409FAF1594854C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	rogid:M4q06jVbWuq1mGMXvtuFBaMEgZM9606	intact-crc:FC0626EA871515F2|rigid:Jfgb2nu4MWuYBnqsnt63a0IKQZw	false	-	sufficient binding region:32-313	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8NA82	uniprotkb:P32502	intact:EBI-2341554|uniprotkb:D3DU09|uniprotkb:Q8N7Z7|uniprotkb:Q8IYS7|ensembl:ENSP00000311496|ensembl:ENSP00000416177	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:marha_human(display_long)|uniprotkb:MARCHF10(gene name)|psi-mi:MARCHF10(display_short)|uniprotkb:MARCH10(gene name synonym)|uniprotkb:Membrane-associated RING finger protein 10(gene name synonym)|uniprotkb:Membrane-associated RING-CH protein X(gene name synonym)|uniprotkb:RING finger protein 190(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase MARCHF10(gene name synonym)|uniprotkb:RNF190(gene name synonym)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11526117|imex:IM-24995-395	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001094345.1|refseq:NP_689811.2|refseq:NP_001275708.1|refseq:NP_001275709.1|ensembl:ENSG00000173838(gene)|ensembl:ENST00000311269(transcript)|ensembl:ENST00000456609(transcript)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016740"(transferase activity)|interpro:IPR011016(Zinc finger, variant RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR042583|entrezgene/locuslink:162333(identity)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	-	-	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:xYNhVYIVxXneNrLbdaSO0uTK9l89606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:14BE4FCB1FD065C0|rigid:3K6aRt9u5yZ2AdstYQGOqazRuOY	false	sufficient binding region:1-657	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8NA61-2	uniprotkb:P32502	intact:EBI-11524851|ensembl:ENSP00000368249|ensembl:ENSP00000480148	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:q8na61-2(display_long)|uniprotkb:CBY2(gene name)|psi-mi:CBY2(display_short)|uniprotkb:SPERT(gene name synonym)|uniprotkb:Spermatid-associated protein(gene name synonym)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11526108|imex:IM-24995-394	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-741724(isoform-parent)|ensembl:ENSG00000174015(gene)|ensembl:ENST00000378966(transcript)|ensembl:ENST00000610924(transcript)|uniprotkb:Q8NA61-2(isoform-parent)|entrezgene/locuslink:220082(identity)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	-	-	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:SogYcXGGMYRYzB9xKC5o0pEtsDs9606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:AECB2487D50A7514|rigid:1B4D21kYGCv/Xe0aARbP71v8ZGY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32502	uniprotkb:Q8N6L0	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	intact:EBI-749265|uniprotkb:Q96MC3|ensembl:ENSP00000404220	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:kash5_human(display_long)|uniprotkb:KASH5(gene name)|psi-mi:KASH5(display_short)|uniprotkb:CCDC155(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 155(gene name synonym)|uniprotkb:KASH domain-containing protein 5(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11526099|imex:IM-24995-393	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	refseq:NP_653289.3|ensembl:ENSG00000161609(gene)|ensembl:ENST00000447857(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034397"(telomere localization)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051225"(spindle assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0090172"(microtubule cytoskeleton organization involved in homologous chromosome segregation)|go:"GO:0090220"(chromosome localization to nuclear envelope involved in homologous chromosome segregation)|go:"GO:0090619"(meiotic spindle pole)|interpro:IPR011992(EF-Hand type)|interpro:IPR028168|interpro:IPR028170|interpro:IPR039508|mint:Q8N6L0|rcsb pdb:6R2I|rcsb pdb:6WMF|entrezgene/locuslink:147872(identity)	-	crc64:A5409FAF1594854C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	rogid:Wl9L7AcvDHCZuKjYLn8QgGIbZTc9606	intact-crc:B89319EE17F82369|rigid:2JxAFY6iMFYY2m55YCnuCUYq+lE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8IYA8	uniprotkb:P32502	intact:EBI-8638439|intact:EBI-28969497|ensembl:ENSP00000296449|ensembl:ENSP00000391788|ensembl:ENSP00000407837|uniprotkb:C9JJL0|uniprotkb:Q96LP7|intact:MINT-8162095|uniprotkb:Q05DG9	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:iho1_human(display_long)|uniprotkb:IHO1(gene name)|psi-mi:IHO1(display_short)|uniprotkb:CCDC36(gene name synonym)|uniprotkb:Cancer/testis antigen 74(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 36(gene name synonym)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11526088|imex:IM-24995-392	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000296449|ensembl:ENST00000366429|ensembl:ENSP00000403700|ensembl:ENSP00000391788|ensembl:ENSP00000407837|ensembl:ENSG00000173421(gene)|ensembl:ENST00000296449(transcript)|ensembl:ENST00000438782(transcript)|ensembl:ENST00000452691(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0006310"(DNA recombination)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0042138"(meiotic DNA double-strand break formation)|go:"GO:0048477"(oogenesis)|go:"GO:0060629"(regulation of homologous chromosome segregation)|interpro:IPR031529|mint:Q8IYA8|refseq:XP_011531974.1|refseq:XP_011531975.1|refseq:NP_001128669.1|refseq:NP_835467.2|refseq:XP_006713187.1|entrezgene/locuslink:339834(identity)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	-	comment:mint	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:+TNQLExkhmC1NWqsE240Cx7zFVU9606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:A86F0BC77DD08738|rigid:aD6ReVsQ4vnRgoWlg+1OttnqWGc	false	sufficient binding region:11-594	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8TAP6	uniprotkb:P32502	intact:EBI-742887|ensembl:ENSP00000262127|uniprotkb:Q658N5|uniprotkb:Q9H9U7|uniprotkb:B0YJB2|uniprotkb:B4DXG5|uniprotkb:B4DZW1	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:cep76_human(display_long)|uniprotkb:CEP76(gene name)|psi-mi:CEP76(display_short)|uniprotkb:C18orf9(gene name synonym)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11526163|imex:IM-24995-399	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_079175.2|ensembl:ENSG00000101624(gene)|ensembl:ENST00000262127(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0046599"(regulation of centriole replication)|interpro:IPR028926|interpro:IPR038765|mint:Q8TAP6|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_001258918.1|entrezgene/locuslink:79959(identity)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	-	-	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:fWzb8oIU35oVWomyDrf8u5sbxUk9606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:F5F4643B56E87EED|rigid:xIEW9O53WNj98bB1gVHS61fa9CM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32502	uniprotkb:Q8NFF5-2	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	intact:EBI-11526128|ensembl:ENSP00000317296	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:q8nff5-2(display_long)|uniprotkb:FLAD1(gene name)|psi-mi:FLAD1(display_short)|uniprotkb:FAD pyrophosphorylase(gene name synonym)|uniprotkb:FMN adenylyltransferase(gene name synonym)|uniprotkb:Flavin adenine dinucleotide synthase(gene name synonym)|uniprotkb:PP591(orf name)|uniprotkb:FADS2(isoform synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11526132|imex:IM-24995-396	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	uniprotkb:Q8NFF5-2(isoform-parent)|intact:EBI-742815(isoform-parent)|ensembl:ENST00000315144(transcript)|ensembl:ENSG00000160688(gene)|entrezgene/locuslink:80308(identity)	-	crc64:A5409FAF1594854C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	rogid:BU/WYJYTvm8VgRPN+e8jjYiw5yU9606	intact-crc:F62CFD5FECFC3157|rigid:LLyV3rv2PbU1E8qBienKt/ARbcE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32502	uniprotkb:Q8NHQ1	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	intact:EBI-739624|ensembl:ENSP00000264982|ensembl:ENSP00000419231|uniprotkb:Q96B31|uniprotkb:Q9H2C3|uniprotkb:Q9H2Z1|uniprotkb:Q9H940|uniprotkb:D3DNE9|uniprotkb:B7Z5I8|uniprotkb:B7Z7E8|uniprotkb:F5GZX8	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:cep70_human(display_long)|uniprotkb:CEP70(gene name)|psi-mi:CEP70(display_short)|uniprotkb:BITE(gene name synonym)|uniprotkb:p10-binding protein(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11526141|imex:IM-24995-397	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	ensembl:ENSG00000114107(gene)|ensembl:ENST00000264982(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|interpro:IPR019734|interpro:IPR037692|mint:Q8NHQ1|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|ensembl:ENST00000484888(transcript)|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_077817.2|refseq:XP_016862764.1|refseq:NP_001275893.1|refseq:NP_001275894.1|refseq:NP_001275895.1|refseq:NP_001275896.1|refseq:NP_001307527.1|refseq:NP_001307529.1|entrezgene/locuslink:80321(identity)	-	crc64:A5409FAF1594854C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	rogid:S4yveQWcvdVtAUX65gqrJ5Dv0Mc9606	intact-crc:436B8CDA32CCE165|rigid:wsx4pXsjZLscupso/4I0ctieg94	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8NHQ1-3	uniprotkb:P32502	intact:EBI-11526150|ensembl:ENSP00000419743	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:q8nhq1-3(display_long)|uniprotkb:CEP70(gene name)|psi-mi:CEP70(display_short)|uniprotkb:BITE(gene name synonym)|uniprotkb:p10-binding protein(gene name synonym)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11526154|imex:IM-24995-398	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114107(gene)|ensembl:ENST00000464035(transcript)|intact:EBI-739624(isoform-parent)|uniprotkb:Q8NHQ1-3(isoform-parent)|entrezgene/locuslink:80321(identity)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	-	-	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:hoF4iYo+GzWQ21hoaWZfTftWKCc9606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:B7E729EE7D43B5C5|rigid:gvbOoDyvh55QDtfHDRmfUJrq5uI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32502	uniprotkb:Q96CD2	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	intact:EBI-724333|uniprotkb:Q96SX0|ensembl:ENSP00000343190|uniprotkb:Q9HC17	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:coac_human(display_long)|uniprotkb:CoaC(gene name synonym)|uniprotkb:PPCDC(gene name)|psi-mi:PPCDC(display_short)|uniprotkb:COAC(gene name synonym)|uniprotkb:MDS018(orf name)|uniprotkb:UNQ9365/PRO34154(orf name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11526208|imex:IM-24995-404	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	refseq:NP_068595.3|rcsb pdb:1QZU|reactome:R-HSA-196783|mint:Q96CD2|ensembl:ENSG00000138621(gene)|ensembl:ENST00000342932(transcript)|go:"GO:0004633"(phosphopantothenoylcysteine decarboxylase activity)|go:"GO:0005829"(cytosol)|go:"GO:0010181"(FMN binding)|go:"GO:0015937"(coenzyme A biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0071513"(phosphopantothenoylcysteine decarboxylase complex)|interpro:IPR003382(Flavoprotein)|interpro:IPR036551|refseq:NP_001288030.1|refseq:NP_001288031.1|refseq:NP_001288032.1|refseq:NP_001288033.1|refseq:NP_001288034.1|entrezgene/locuslink:60490(identity)	-	crc64:A5409FAF1594854C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	rogid:2d686R1m4jA5uWpf/8O6rI6/Olo9606	intact-crc:4C28742D3AA24E92|rigid:bGg5IRa1rTNv8sVIwXENQbKQ60M	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96BR9	uniprotkb:P32502	intact:EBI-742740|uniprotkb:Q8IUL5|uniprotkb:Q8IWR9|uniprotkb:Q8N2Y5|uniprotkb:Q96BX0|ensembl:ENSP00000362609	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:zbt8a_human(display_long)|uniprotkb:ZBTB8A(gene name)|psi-mi:ZBTB8A(display_short)|uniprotkb:BOZF1(gene name synonym)|uniprotkb:BTB/POZ and zinc-finger domain-containing factor(gene name synonym)|uniprotkb:BTB/POZ and zinc-finger domains factor on chromosome 1(gene name synonym)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11526199|imex:IM-24995-403	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000160062(gene)|ensembl:ENST00000373510(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|refseq:NP_001035531.2|refseq:NP_001278425.1|entrezgene/locuslink:653121(identity)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	-	-	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:tsrPT2tHvuBryODKgRXnceXz9s09606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:3B05742E5928BE39|rigid:pGUYzMu13b6NYTUZKoG4AcVut4o	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32502	uniprotkb:Q8WXE1-3	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	intact:EBI-11524582|ensembl:ENSP00000400930	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:q8wxe1-3(display_long)|uniprotkb:ATRIP(gene name)|psi-mi:ATRIP(display_short)|uniprotkb:AGS1(gene name synonym)|uniprotkb:ATM and Rad3-related-interacting protein(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11526172|imex:IM-24995-400	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	intact:EBI-747353(isoform-parent)|ensembl:ENSG00000164053(gene)|ensembl:ENST00000412052(transcript)|entrezgene/locuslink:84126(identity)	-	crc64:A5409FAF1594854C	isoform-comment:No experimental confirmation available.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	rogid:NKCjy1jGZEySEhUOf8rJ6h9pyxY9606	intact-crc:5F53C0A6661B4508|rigid:8PRM6TuIS7PPBbI7W0s2tbT/MLs	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q969V4	uniprotkb:P32502	intact:EBI-10180409|uniprotkb:D3DTM7|ensembl:ENSP00000341346	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:tekt1_human(display_long)|uniprotkb:TEKT1(gene name)|psi-mi:TEKT1(display_short)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11526181|imex:IM-24995-401	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_444515.1|ensembl:ENSG00000167858(gene)|ensembl:ENST00000338694(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0031514"(motile cilium)|go:"GO:0060271"(cilium assembly)|go:"GO:0060294"(cilium movement involved in cell motility)|interpro:IPR000435(Tektin)|entrezgene/locuslink:83659(identity)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	-	-	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:5hh7T1hcmqrmmiOtJTT1OokmPrU9606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:8BBC913B2DFB695E|rigid:WCtLXYrTqxxPifGCBEDTzthl8bg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96AT9	uniprotkb:P32502	intact:EBI-372480|uniprotkb:O43767|uniprotkb:Q8N215|uniprotkb:Q96N34|uniprotkb:Q9BSB5|uniprotkb:B4E016|ensembl:ENSP00000352401|uniprotkb:A8K4S0|uniprotkb:C9JPQ7|uniprotkb:Q53TV9	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:rpe_human(display_long)|uniprotkb:Ribulose-5-phosphate-3-epimerase(gene name synonym)|uniprotkb:RPE(gene name)|psi-mi:RPE(display_short)|uniprotkb:HUSSY-17(orf name)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11526190|imex:IM-24995-402	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000197713(gene)|ensembl:ENST00000359429(transcript)|go:"GO:0004750"(D-ribulose-phosphate 3-epimerase activity)|go:"GO:0005829"(cytosol)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006098"(pentose-phosphate shunt)|go:"GO:0009052"(pentose-phosphate shunt, non-oxidative branch)|go:"GO:0019323"(pentose catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044262"(cellular carbohydrate metabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000056(Ribulose-phosphate 3-epimerase)|interpro:IPR011060(Ribulose-phosphate binding barrel)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR026019|rcsb pdb:3OVP|rcsb pdb:3OVQ|rcsb pdb:3OVR|rcsb pdb:3QC3|reactome:R-HSA-71336|refseq:NP_008847.1|refseq:NP_954699.1|refseq:NP_001305855.1|refseq:NP_001305856.1|refseq:NP_001305857.1|refseq:NP_001305858.1|refseq:NP_001305859.1|refseq:NP_001305860.1|refseq:NP_001265211.1|refseq:NP_001265212.1|refseq:NP_001265214.1|refseq:NP_001265215.1|refseq:NP_001265217.1|refseq:NP_001265218.1|refseq:XP_006712740.1|entrezgene/locuslink:6120(identity)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	-	-	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:lFQZZpLsSKKpUv9o+wSEvPlqG989606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:60ABEAE8A08BE3AB|rigid:pD+x8gZiGJrTozR0guYJRc/6Mgs	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32502	uniprotkb:Q96HA8	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	intact:EBI-741158|uniprotkb:B4DE68|uniprotkb:Q9NW95|ensembl:ENSP00000287387	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:ntaq1_human(display_long)|uniprotkb:NTAQ1(gene name)|psi-mi:NTAQ1(display_short)|uniprotkb:C8orf32(gene name synonym)|uniprotkb:Protein NH2-terminal glutamine deamidase(gene name synonym)|uniprotkb:WDYHV motif-containing protein 1(gene name synonym)|uniprotkb:WDYHV1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11526241|imex:IM-24995-407	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	refseq:NP_060494.1|refseq:NP_001269953.1|ensembl:ENSG00000156795(gene)|ensembl:ENST00000287387(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0008418"(protein-N-terminal asparagine amidohydrolase activity)|interpro:IPR023128|interpro:IPR037132|interpro:IPR039733|mint:Q96HA8|rcsb pdb:3C9Q|rcsb pdb:4W79|rcsb pdb:6KGJ|go:"GO:0070773"(protein-N-terminal glutamine amidohydrolase activity)|entrezgene/locuslink:55093(identity)	-	crc64:A5409FAF1594854C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	rogid:RKX6ww+Z/Zw6bmOXa0r8C0mxlvc9606	intact-crc:CC05A3DBA45ED3DB|rigid:xjYCO1ebvGyeUhWxDtdeHBql7yk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96CG3	uniprotkb:P32502	intact:EBI-740711|ensembl:ENSP00000354911|ensembl:ENSP00000424231	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:tifa_human(display_long)|uniprotkb:Putative NF-kappa-B-activating protein 20(gene name synonym)|uniprotkb:TIFA(gene name)|psi-mi:TIFA(display_short)|uniprotkb:T2BP(gene name synonym)|uniprotkb:TRAF2-binding protein(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM14(gene name synonym)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11526217|imex:IM-24995-405	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_443096.1|ensembl:ENSG00000145365(gene)|ensembl:ENST00000361717(transcript)|ensembl:ENST00000500655(transcript)|go:"GO:0002753"(cytoplasmic pattern recognition receptor signaling pathway)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0051260"(protein homooligomerization)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR033621|rcsb pdb:4YM4|rcsb pdb:4ZGI|rcsb pdb:5ZUJ|rcsb pdb:6A33|reactome:R-HSA-9645460|dip:DIP-40185N|entrezgene/locuslink:92610(identity)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	-	-	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:ppKFaTK8YYWSscDQlE1n/mONziY9606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:FB2D6C1FC2D28134|rigid:2KA272tjgq17guvrGjv0gA6SP4E	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96EY1-3	uniprotkb:P32502	intact:EBI-11526226|ensembl:ENSP00000393970	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:q96ey1-3(display_long)|uniprotkb:DnaJ protein Tid-1(gene name synonym)|uniprotkb:HCA57(gene name synonym)|uniprotkb:Hepatocellular carcinoma-associated antigen 57(gene name synonym)|uniprotkb:TID1(gene name synonym)|uniprotkb:Tumorous imaginal discs protein Tid56 homolog(gene name synonym)|uniprotkb:DNAJA3(gene name)|psi-mi:DNAJA3(display_short)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11526230|imex:IM-24995-406	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-356767(isoform-parent)|ensembl:ENSG00000103423(gene)|ensembl:ENST00000431375(transcript)|uniprotkb:Q96EY1-3(isoform-parent)|entrezgene/locuslink:9093(identity)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	-	isoform-comment:"Ref.3 (BAG58345) sequence is in conflict in position: 33:Y->H."	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:nMH4IaOZYO5w5bh+cdX4LoPSisc9606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:566B360792F779F4|rigid:aTXYAL3WN3g4e2tWaFZyCDv0gP0	false	sufficient binding region:60-300	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32502	uniprotkb:Q96QF0-2	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	intact:EBI-747865|ensembl:ENSP00000247833	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:q96qf0-2(display_long)|uniprotkb:alpha1(isoform synonym)|uniprotkb:RAB3IP(gene name)|psi-mi:RAB3IP(display_short)|uniprotkb:Rabin-3(gene name synonym)|uniprotkb:SSX2-interacting protein(gene name synonym)|uniprotkb:RABIN8(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11526268|imex:IM-24995-410	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	intact:EBI-747844(rab3i_human)|ensembl:ENSG00000127328(gene)|ensembl:ENST00000247833(transcript)|uniprotkb:Q96QF0-2(isoform-parent)|entrezgene/locuslink:117177(identity)	-	crc64:A5409FAF1594854C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	rogid:Vpmox/vANEwz2l+XaBdJslXrwyo9606	intact-crc:BDFE692736555764|rigid:RCBuD0oAg2xoF8AhY+F76pm7vTg	false	-	sufficient binding region:207-460	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96HD9	uniprotkb:P32502	intact:EBI-3916242|ensembl:ENSP00000255082	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:acy3_human(display_long)|uniprotkb:ACY3(gene name)|psi-mi:ACY3(display_short)|uniprotkb:Aspartoacylase-2(gene name synonym)|uniprotkb:ASPA2(gene name synonym)|uniprotkb:Acylase III(gene name synonym)|uniprotkb:Aminoacylase-3(gene name synonym)|uniprotkb:Hepatitis C virus core-binding protein 1(gene name synonym)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11526250|imex:IM-24995-408	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_542389.1|ensembl:ENSG00000132744(gene)|ensembl:ENST00000255082(transcript)|go:"GO:0004046"(aminoacylase activity)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016788"(hydrolase activity, acting on ester bonds)|go:"GO:0016811"("hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides")|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR007036(Succinylglutamate desuccinylase/aspartoacylase)|interpro:IPR016708(Aspartoacylase)|mint:Q96HD9|reactome:R-HSA-5423646|go:"GO:0005829"(cytosol)|entrezgene/locuslink:91703(identity)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	-	-	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Zjs7m7GTDeoVuV1/ggtGOu1LRhM9606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:68B3D1F44BB9E0D4|rigid:Lbvd1J6/Qa1iLlH2qOS4/t3acXI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32502	uniprotkb:Q96HR9	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	intact:EBI-750345|uniprotkb:Q96LM0|uniprotkb:B2RE01|uniprotkb:A0A1L5BXV3|uniprotkb:D6W5Z0|ensembl:ENSP00000378861	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:reep6_human(display_long)|uniprotkb:Polyposis locus protein 1-like 1(gene name synonym)|uniprotkb:REEP6(gene name)|psi-mi:REEP6(display_short)|uniprotkb:C19orf32(gene name synonym)|uniprotkb:DP1L1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11526259|imex:IM-24995-409	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	refseq:NP_612402.1|refseq:NP_001316485.1|ensembl:ENSG00000115255(gene)|ensembl:ENST00000395479(transcript)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030665"(clathrin-coated vesicle membrane)|go:"GO:0032386"(regulation of intracellular transport)|go:"GO:0050908"(detection of light stimulus involved in visual perception)|interpro:IPR004345(TB2/DP1 and HVA22 related protein)|mint:Q96HR9|reactome:R-HSA-381753|go:"GO:0005634"(nucleus)|entrezgene/locuslink:92840(identity)	-	crc64:A5409FAF1594854C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2017/05/05	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	rogid:pB8AjjNTpmaaLJ8j7MCBM45UAHE9606	intact-crc:07C534F9A44ADC6D|rigid:6hotnndLX78u2i77ARKqwuySncI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9H0E2	uniprotkb:P32502	intact:EBI-74615|ensembl:ENSP00000314733|uniprotkb:Q9H9E6|uniprotkb:Q9UJ69|uniprotkb:B3KXC6	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:tolip_human(display_long)|uniprotkb:TOLLIP(gene name)|psi-mi:TOLLIP(display_short)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11526306|imex:IM-24995-414	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000078902(gene)|ensembl:ENST00000317204(transcript)|go:"GO:0005150"(interleukin-1, type I receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006914"(autophagy)|go:"GO:0007165"(signal transduction)|go:"GO:0016310"(phosphorylation)|go:"GO:0016604"(nuclear body)|go:"GO:0019900"(kinase binding)|go:"GO:0006954"(inflammatory response)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032183"(SUMO binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0035580"(specific granule lumen)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045321"(leukocyte activation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070498"(interleukin-1-mediated signaling pathway)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR009060(UBA-like)|interpro:IPR035892|interpro:IPR037301|interpro:IPR041799|rcsb pdb:1WGL|rcsb pdb:2N31|reactome:R-HSA-6798695|reactome:R-HSA-9020702|refseq:NP_061882.2|refseq:NP_001305441.1|refseq:NP_001305443.1|refseq:NP_001305444.1|refseq:NP_001305445.1|dip:DIP-30845N|entrezgene/locuslink:54472(identity)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	-	-	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:HR6/CGVYMtuDqxW44fBD/KjScnk9606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:C7DE7D1CF1D1C18C|rigid:10OUQ1rGrklUcPLFH/qVdVfhXPU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32502	uniprotkb:Q9BPX1	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	intact:EBI-742664|uniprotkb:Q9UKU3|ensembl:ENSP00000263278	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:dhb14_human(display_long)|uniprotkb:DHRS10(gene name synonym)|uniprotkb:Dehydrogenase/reductase SDR family member 10(gene name synonym)|uniprotkb:17-beta-hydroxysteroid dehydrogenase DHRS10(gene name synonym)|uniprotkb:Retinal short-chain dehydrogenase/reductase retSDR3(gene name synonym)|uniprotkb:HSD17B14(gene name)|psi-mi:HSD17B14(display_short)|uniprotkb:SDR3(gene name synonym)|uniprotkb:SDR47C1(gene name synonym)|uniprotkb:Short chain dehydrogenase/reductase family 47C member 1(gene name synonym)|uniprotkb:UNQ502/PRO474(orf name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11526279|imex:IM-24995-411	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	refseq:NP_057330.2|ensembl:ENSG00000087076(gene)|ensembl:ENST00000263278(transcript)|go:"GO:0004303"(estradiol 17-beta-dehydrogenase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006706"(steroid catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0044594"("17-beta-hydroxysteroid dehydrogenase (NAD+) activity")|go:"GO:0047045"("testosterone 17-beta-dehydrogenase (NADP+) activity")|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR020904|interpro:IPR036291|rcsb pdb:1YDE|rcsb pdb:5EN4|rcsb pdb:5HS6|rcsb pdb:5ICM|rcsb pdb:5ICS|rcsb pdb:5JS6|rcsb pdb:5JSF|rcsb pdb:5L7T|rcsb pdb:5L7W|rcsb pdb:5L7Y|rcsb pdb:5O42|rcsb pdb:5O43|rcsb pdb:5O6O|rcsb pdb:5O6X|rcsb pdb:5O6Z|rcsb pdb:5O72|rcsb pdb:5O7C|rcsb pdb:6EMM|rcsb pdb:6FFB|rcsb pdb:6G4L|rcsb pdb:6GBT|rcsb pdb:6GTB|rcsb pdb:6GTU|rcsb pdb:6H0M|rcsb pdb:6HNO|rcsb pdb:6QCK|rcsb pdb:6ZDE|rcsb pdb:6ZDI|reactome:R-HSA-193144|entrezgene/locuslink:51171(identity)	-	crc64:A5409FAF1594854C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	rogid:/t03kHO/EWlqKNv7+TkWbTV9jpM9606	intact-crc:CB4C06D66D4C0BAB|rigid:vs25FILt8u/ffJMBLpyvWk9P8Cs	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32502	uniprotkb:Q9BQC3	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	intact:EBI-10237931|uniprotkb:O60623|uniprotkb:B4DNI8|uniprotkb:B2RDE3|uniprotkb:A8MVC9|ensembl:ENSP00000255108	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:dph2_human(display_long)|uniprotkb:Diphthamide biosynthesis protein 2(gene name synonym)|uniprotkb:Diphtheria toxin resistance protein 2(gene name synonym)|uniprotkb:DPH2(gene name)|psi-mi:DPH2(display_short)|uniprotkb:DPH2L2(gene name synonym)|uniprotkb:"S-adenosyl-L-methionine:L-histidine 3-amino-3-carboxypropyltransferase 2"(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11526288|imex:IM-24995-412	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	refseq:NP_001306095.1|refseq:NP_001306098.1|refseq:NP_001034678.1|refseq:NP_001375.2|ensembl:ENSG00000132768(gene)|ensembl:ENST00000255108(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0017183"(peptidyl-diphthamide biosynthetic process from peptidyl-histidine)|go:"GO:0090560"("2-(3-amino-3-carboxypropyl)histidine synthase activity")|interpro:IPR010014(Diphthamide synthesis, DHP2)|interpro:IPR016435(Diphthamide synthesis, DHP1)|interpro:IPR042263|interpro:IPR042265|reactome:R-HSA-5358493|entrezgene/locuslink:1802(identity)	-	crc64:A5409FAF1594854C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	rogid:/Z9UhAa8qkHe3rPFS3OPfiJ4RFM9606	intact-crc:16B364A8E8BD451B|rigid:nG0On3X0/CoAisHrSzA34Kvk14s	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9BQD3	uniprotkb:P32502	intact:EBI-739657|uniprotkb:O76098|ensembl:ENSP00000472678|ensembl:ENSP00000472836|ensembl:ENSP00000222307|ensembl:ENSP00000438903|ensembl:ENSP00000443549|ensembl:ENSP00000468990|ensembl:ENSP00000471554	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:kxdl1_human(display_long)|uniprotkb:KXD1(gene name)|psi-mi:KXD1(display_short)|uniprotkb:C19orf50(gene name synonym)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11526297|imex:IM-24995-413	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001165419.1|refseq:NP_001165420.1|refseq:NP_076974.2|ensembl:ENST00000222307(transcript)|ensembl:ENST00000539106(transcript)|ensembl:ENST00000540691(transcript)|ensembl:ENST00000595073(transcript)|ensembl:ENST00000599319(transcript)|ensembl:ENST00000600654(transcript)|ensembl:ENST00000602094(transcript)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0032418"(lysosome localization)|go:"GO:0099078"(BORC complex)|interpro:IPR019371|interpro:IPR039843|ensembl:ENSG00000105700(gene)|refseq:XP_016882770.1|refseq:XP_011526574.1|refseq:XP_011526575.1|refseq:XP_006722946.1|entrezgene/locuslink:79036(identity)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	-	-	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:5BoR6AN0Ywb1eI04Rw4chmlWVI09606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:D800A68D9FF581E5|rigid:/PHNZMGCVLir4/q0DlagUS4LjNQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32502	uniprotkb:Q9NRG1	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	intact:EBI-739759|uniprotkb:Q53HA7|uniprotkb:Q59EL9|uniprotkb:Q5VV18|uniprotkb:Q5VV20|uniprotkb:B7Z1Z3|ensembl:ENSP00000318602	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:prdc1_human(display_long)|uniprotkb:PRTFDC1(gene name)|psi-mi:PRTFDC1(display_short)|uniprotkb:HHGP(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11526346|imex:IM-24995-418	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	refseq:NP_001269715.1|refseq:NP_064585.1|ensembl:ENSG00000099256(gene)|ensembl:ENST00000320152(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0006166"(purine ribonucleoside salvage)|go:"GO:0042803"(protein homodimerization activity)|interpro:IPR000836(Phosphoribosyltransferase)|interpro:IPR005904(Hypoxanthine phosphoribosyl transferase)|interpro:IPR029057|rcsb pdb:2JBH|entrezgene/locuslink:56952(identity)	-	crc64:A5409FAF1594854C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	rogid:grTZnSalFILRSeeZBjM1mTtF0xo9606	intact-crc:187C8BC55425D194|rigid:zxrZ2roKd1hs5E5IEnuM1CbHXBk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9H773	uniprotkb:P32502	intact:EBI-723569|intact:EBI-1384169|ensembl:ENSP00000322524	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:dctp1_human(display_long)|uniprotkb:DCTPP1(gene name)|psi-mi:DCTPP1(display_short)|uniprotkb:RS21C6(gene name synonym)|uniprotkb:CDA03(orf name)|uniprotkb:XTP3TPA(gene name synonym)|uniprotkb:Deoxycytidine-triphosphatase 1(gene name synonym)|uniprotkb:XTP3-transactivated gene A protein(gene name synonym)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11526315|imex:IM-24995-415	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_077001.1|ensembl:ENST00000319285(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006253"(dCTP catabolic process)|go:"GO:0009143"(nucleoside triphosphate catabolic process)|go:"GO:0032556"(pyrimidine deoxyribonucleotide binding)|go:"GO:0042262"(DNA protection)|go:"GO:0042802"(identical protein binding)|go:"GO:0047429"(nucleoside-triphosphate diphosphatase activity)|go:"GO:0047840"(dCTP diphosphatase activity)|interpro:IPR025984|mint:Q9H773|reactome:R-HSA-499943|ensembl:ENSG00000179958(gene)|entrezgene/locuslink:79077(identity)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	-	-	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:4EfV2ZU2MgDiFXShthfualZnat09606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:B9AC6B436502830C|rigid:prSEHirUfm6oCGHNCI6tZroyySY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32502	uniprotkb:Q9NPJ6	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	intact:EBI-394607|uniprotkb:Q9BS95|uniprotkb:Q9NYR5|uniprotkb:Q53GB4|uniprotkb:Q53H68|uniprotkb:Q5T912|uniprotkb:Q6FHC4|uniprotkb:Q6IA79|uniprotkb:B4DX67|ensembl:ENSP00000258648	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:med4_human(display_long)|uniprotkb:HSPC126(orf name)|uniprotkb:DRIP36(gene name synonym)|uniprotkb:MED4(gene name)|psi-mi:MED4(display_short)|uniprotkb:ARC36(gene name synonym)|uniprotkb:Mediator complex subunit 4(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex 36 kDa component(gene name synonym)|uniprotkb:Activator-recruited cofactor 36 kDa component(gene name synonym)|uniprotkb:TRAP/SMCC/PC2 subunit p36 subunit(gene name synonym)|uniprotkb:VDRIP(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11526324|imex:IM-24995-416	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	refseq:NP_001257558.1|refseq:NP_054885.1|ensembl:ENSG00000136146(gene)|ensembl:ENST00000258648(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0070847"(core mediator complex)|interpro:IPR019258|mint:Q9NPJ6|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|entrezgene/locuslink:29079(identity)	-	crc64:A5409FAF1594854C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	rogid:Bept2Oec50gruA9e4pf+eEUiANM9606	intact-crc:63EF973D20EE6DC7|rigid:+53+PRs9H9BVSg/T98CNrYqG7DA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9NQC3-3	uniprotkb:P32502	intact:EBI-11526335|ensembl:ENSP00000378107	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:q9nqc3-3(display_long)|uniprotkb:Foocen(gene name synonym)|uniprotkb:KIAA0886(gene name synonym)|uniprotkb:NOGO(gene name synonym)|uniprotkb:Neurite outgrowth inhibitor(gene name synonym)|uniprotkb:Neuroendocrine-specific protein(gene name synonym)|uniprotkb:Neuroendocrine-specific protein C homolog(gene name synonym)|uniprotkb:RTN-x(gene name synonym)|uniprotkb:Reticulon-5(gene name synonym)|uniprotkb:My043(orf name)|uniprotkb:SP1507(orf name)|uniprotkb:Foocen-S(isoform synonym)|uniprotkb:Nogo-C(isoform synonym)|uniprotkb:RTN4(gene name)|psi-mi:RTN4(display_short)|uniprotkb:RTN4C(isoform synonym)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11526333|imex:IM-24995-417	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-715945(isoform-parent)|ensembl:ENSG00000115310(gene)|ensembl:ENST00000394609(transcript)|entrezgene/locuslink:57142(identity)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	-	-	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Iq/LlFtXjFyIIfxZ1l3NTKURpyA9606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:F48BB9FB0EE20469|rigid:vyF0xIDaWGKzxa2afM0/ZpIdraI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32502	uniprotkb:Q9NVV9	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	intact:EBI-741515|uniprotkb:Q53FQ1|uniprotkb:Q6IA99|ensembl:ENSP00000254250|uniprotkb:A6NCB6|uniprotkb:D3DSY5|uniprotkb:H9KV49	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:thap1_human(display_long)|uniprotkb:THAP1(gene name)|psi-mi:THAP1(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11526382|imex:IM-24995-422	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	refseq:NP_060575.1|ensembl:ENSG00000131931(gene)|ensembl:ENST00000254250(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001650"(fibrillar center)|go:"GO:0001935"(endothelial cell proliferation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007049"(cell cycle)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016605"(PML body)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR006612(Zinc finger, C2CH-type)|interpro:IPR026516|interpro:IPR038441|mint:Q9NVV9|rcsb pdb:2JTG|rcsb pdb:2KO0|rcsb pdb:2L1G|refseq:NP_945354.1|entrezgene/locuslink:55145(identity)	-	crc64:A5409FAF1594854C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	rogid:/KO90pu5tBnIVq9SMx1JYPXFCEQ9606	intact-crc:E8EAE968D34B5E6D|rigid:WfQwtYrbxl994hjGKdwyREUxCyI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32502	uniprotkb:Q9NRY6	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	intact:EBI-750734|uniprotkb:Q567U0|uniprotkb:Q8NBW6|uniprotkb:Q96F13|uniprotkb:A8K252|ensembl:ENSP00000316021|ensembl:ENSP00000459019|ensembl:ENSP00000459419|ensembl:ENSP00000491350|ensembl:ENSP00000491393|ensembl:ENSP00000492026|ensembl:ENSP00000492083|ensembl:ENSP00000483743	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:pls3_human(display_long)|uniprotkb:"Ca(2+)-dependent phospholipid scramblase 3"(gene name synonym)|uniprotkb:PLSCR3(gene name)|psi-mi:PLSCR3(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11526355|imex:IM-24995-419	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	refseq:NP_001188505.1|refseq:NP_065093.2|ensembl:ENSG00000187838(gene)|ensembl:ENSG00000284009(gene)|ensembl:ENST00000324822(transcript)|ensembl:ENST00000574401(transcript)|ensembl:ENST00000576201(transcript)|ensembl:ENST00000619711(transcript)|ensembl:ENST00000639780(transcript)|ensembl:ENST00000639874(transcript)|ensembl:ENST00000640053(transcript)|ensembl:ENST00000640375(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017121"(plasma membrane phospholipid scrambling)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0017128"(phospholipid scramblase activity)|go:"GO:0032049"(cardiolipin biosynthetic process)|go:"GO:0032791"(lead ion binding)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043621"(protein self-association)|go:"GO:0045340"(mercury ion binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0090199"(regulation of release of cytochrome c from mitochondria)|interpro:IPR005552(Scramblase)|entrezgene/locuslink:57048(identity)	-	crc64:A5409FAF1594854C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	rogid:JKzacFCwrCQpcI3EJsLvpAbLFCA9606	intact-crc:C62124A8FC6397FA|rigid:J7CqgW3akkZCt3ZZ9/kD37ajjBI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9NSC5	uniprotkb:P32502	intact:EBI-748420|uniprotkb:O14580|uniprotkb:O95350|uniprotkb:Q9NSB9|uniprotkb:Q9NSC0|intact:EBI-2557809|uniprotkb:E9PCW9|uniprotkb:Q9NSC1|intact:EBI-28972925|ensembl:ENSP00000376162|ensembl:ENSP00000439937|ensembl:ENSP00000446026|intact:EBI-10175777|uniprotkb:B2RA10	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:home3_human(display_long)|uniprotkb:HOMER3(gene name)|psi-mi:HOMER3(display_short)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11526364|imex:IM-24995-420	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000221222|ensembl:ENSP00000221222|ensembl:ENSP00000376162|ensembl:ENST00000433218|ensembl:ENSP00000396154|ensembl:ENSP00000439937|ensembl:ENSP00000446026|ensembl:ENST00000594439|ensembl:ENSP00000471835|refseq:XP_006723006.1|refseq:XP_006723007.1|refseq:NP_001139193.1|refseq:NP_001139194.1|refseq:NP_004829.3|refseq:NP_001139196.1|ensembl:ENSG00000051128(gene)|ensembl:ENST00000392351(transcript)|ensembl:ENST00000539827(transcript)|ensembl:ENST00000542541(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006605"(protein targeting)|go:"GO:0007216"(G protein-coupled glutamate receptor signaling pathway)|go:"GO:0014069"(postsynaptic density)|go:"GO:0030425"(dendrite)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0035256"(G protein-coupled glutamate receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|go:"GO:2001256"(regulation of store-operated calcium entry)|interpro:IPR000697(EVH1)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR044100|mint:Q9NSC5|rcsb pdb:2P8V|rcsb pdb:3CVF|reactome:R-HSA-6794361|entrezgene/locuslink:9454(identity)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	-	-	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:U1y/y52nnf7zQUCNQlqk7JDgXi49606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:8935AC69D6D48836|rigid:nQ/5cQZN/Z9bvMLr5D5+hLXF3n0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32502	uniprotkb:Q9NTM9	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	intact:EBI-714918|uniprotkb:Q5TCZ8|uniprotkb:Q9Y321|ensembl:ENSP00000359507	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:cutc_human(display_long)|uniprotkb:CUTC(gene name)|psi-mi:CUTC(display_short)|uniprotkb:CGI-32(orf name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11526373|imex:IM-24995-421	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	ensembl:ENSG00000119929(gene)|ensembl:ENST00000370476(transcript)|go:"GO:0005507"(copper ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006825"(copper ion transport)|go:"GO:0051262"(protein tetramerization)|go:"GO:0055070"(copper ion homeostasis)|interpro:IPR005627(CutC)|interpro:IPR023648|interpro:IPR036822|mint:Q9NTM9|refseq:NP_057044.2|reactome:R-HSA-936837|rcsb pdb:3IWP|entrezgene/locuslink:51076(identity)	-	crc64:A5409FAF1594854C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	rogid:MkxQTQ5IGq+/IZzPy3wSurdtB6w9606	intact-crc:BB448A3BA4F1801C|rigid:QuTE3NJKYsTVaEHhlnQxe8Ufvpc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32502	uniprotkb:Q9UHX1-5	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	intact:EBI-11526420|ensembl:ENSP00000395417|ensembl:ENSP00000478209	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:q9uhx1-5(display_long)|uniprotkb:PUF60(gene name)|psi-mi:PUF60(display_short)|uniprotkb:"60 kDa poly(U)-binding-splicing factor"(gene name synonym)|uniprotkb:FIR(gene name synonym)|uniprotkb:FUSE-binding protein-interacting repressor(gene name synonym)|uniprotkb:ROBPI(gene name synonym)|uniprotkb:Ro-binding protein 1(gene name synonym)|uniprotkb:SIAHBP1(gene name synonym)|uniprotkb:Siah-binding protein 1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11526418|imex:IM-24995-426	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	intact:EBI-1053259(isoform-parent)|ensembl:ENSG00000179950(gene)|ensembl:ENSG00000274081(gene)|ensembl:ENST00000456095(transcript)|ensembl:ENST00000620953(transcript)|entrezgene/locuslink:22827(identity)	-	crc64:A5409FAF1594854C	isoform-comment:"Contains a glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) at position 14."	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	rogid:PSbIU++DIL6ysF0ccd3ZHzeJ5rs9606	intact-crc:E651F85F81BDC52A|rigid:PzoP+QJrcfD3B9lJsjj4mbQViMs	false	-	sufficient binding region:15-530	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9NWS6	uniprotkb:P32502	intact:EBI-8638992|uniprotkb:B4DY02|ensembl:ENSP00000216214|ensembl:ENSP00000395892|intact:MINT-8162875|uniprotkb:Q5TII5|uniprotkb:B3KWG4|uniprotkb:Q96CY3	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:f118a_human(display_long)|uniprotkb:FAM118A(gene name)|psi-mi:FAM118A(display_short)|uniprotkb:C22orf8(gene name synonym)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11526391|imex:IM-24995-423	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000100376(gene)|ensembl:ENST00000216214(transcript)|ensembl:ENST00000441876(transcript)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|interpro:IPR033353|interpro:IPR038916|interpro:IPR039444|refseq:NP_060381.2|refseq:NP_001098065.1|entrezgene/locuslink:55007(identity)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	-	comment:mint	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:zZMOyeZwAeoDNLBQ9EKYRw4+0BM9606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:72CCF9035DDE69F7|rigid:r/x3t0aXwgqnxLaZbMM7TomZnds	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9P286	uniprotkb:P32502	intact:EBI-741896|ensembl:ENSP00000322957|ensembl:ENSP00000367679|ensembl:ENSP00000367686|intact:EBI-1051061|uniprotkb:A8K5T6|uniprotkb:D3DW14|uniprotkb:Q5W115|uniprotkb:Q8TB93|uniprotkb:Q9BX09|uniprotkb:Q9ULF6	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:pak5_human(display_long)|uniprotkb:PAK5(gene name)|psi-mi:PAK5(display_short)|uniprotkb:KIAA1264(gene name synonym)|uniprotkb:PAK7(gene name synonym)|uniprotkb:p21-activated kinase 5(gene name synonym)|uniprotkb:p21-activated kinase 7(gene name synonym)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11526400|imex:IM-24995-424	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000101349(gene)|go:"GO:0045202"(synapse)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR028754|interpro:IPR033923|interpro:IPR036936|rcsb pdb:2F57|reactome:R-HSA-428540|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013405|reactome:R-HSA-9013407|go:"GO:0043408"(regulation of MAPK cascade)|ensembl:ENST00000353224(transcript)|ensembl:ENST00000378423(transcript)|ensembl:ENST00000378429(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007165"(signal transduction)|go:"GO:0007612"(learning)|go:"GO:0007613"(memory)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016477"(cell migration)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0035556"(intracellular signal transduction)|refseq:NP_065074.1|refseq:NP_817127.1|refseq:XP_016883449.1|refseq:XP_016883450.1|refseq:XP_016883451.1|refseq:XP_016883452.1|refseq:XP_016883453.1|refseq:XP_016883454.1|entrezgene/locuslink:57144(identity)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	-	-	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2017/06/28	rogid:xxNDwmHn4jv8toBmviGjFwBU32E9606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:08EDF5464AF6BDC8|rigid:b6e7eWLgobYY9K2Dq57PbP/v+1I	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UDV6	uniprotkb:P32502	intact:EBI-1640204|uniprotkb:Q13396|uniprotkb:Q8N664|uniprotkb:B2RCF4|ensembl:ENSP00000338572	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:zn212_human(display_long)|uniprotkb:ZNF212(gene name)|psi-mi:ZNF212(display_short)|uniprotkb:ZNFC150(gene name synonym)|uniprotkb:Zinc finger protein C2H2-150(gene name synonym)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11526409|imex:IM-24995-425	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_036388.2|ensembl:ENSG00000170260(gene)|ensembl:ENST00000335870(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR022137|interpro:IPR036051|interpro:IPR036236|mint:Q9UDV6|reactome:R-HSA-212436|entrezgene/locuslink:7988(identity)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	-	-	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:jZtScr5t/MR83+d1tdA9OiP4JCA9606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:6C958FF02FE8E554|rigid:hz8jvORgxHnLSOF79Y5sMHeFAbc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32502	uniprotkb:Q9UHX1-6	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	intact:EBI-11085298|ensembl:ENSP00000431960	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:q9uhx1-6(display_long)|uniprotkb:PUF60(gene name)|psi-mi:PUF60(display_short)|uniprotkb:"60 kDa poly(U)-binding-splicing factor"(gene name synonym)|uniprotkb:FIR(gene name synonym)|uniprotkb:FUSE-binding protein-interacting repressor(gene name synonym)|uniprotkb:ROBPI(gene name synonym)|uniprotkb:Ro-binding protein 1(gene name synonym)|uniprotkb:SIAHBP1(gene name synonym)|uniprotkb:Siah-binding protein 1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11526433|imex:IM-24995-427	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	ensembl:ENSG00000179950(gene)|ensembl:ENST00000527197(transcript)|intact:EBI-1053259(isoform-parent)|uniprotkb:Q9UHX1-6(isoform-parent)|entrezgene/locuslink:22827(identity)	-	crc64:A5409FAF1594854C	isoform-comment:"Contains a glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) at position 14."	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	rogid:rSsTImwmpEAWMCxLzF5Y4zVdeFM9606	intact-crc:B36F8CF05838E75B|rigid:t73OVeVNVLQvgjkmczlo9d3vUIw	false	-	sufficient binding region:15-513	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32502	uniprotkb:Q9UI14	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	intact:EBI-712367|ensembl:ENSP00000222008|uniprotkb:Q7Z4Y2|uniprotkb:Q9Y3R1	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:praf1_human(display_long)|uniprotkb:PRA1 family protein 1(gene name synonym)|uniprotkb:RABAC1(gene name)|psi-mi:RABAC1(display_short)|uniprotkb:PRA1(gene name synonym)|uniprotkb:PRAF1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11526444|imex:IM-24995-428	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	refseq:NP_006414.2|ensembl:ENSG00000105404(gene)|ensembl:ENST00000222008(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0070064"(proline-rich region binding)|interpro:IPR004895(Prenylated rab acceptor PRA1)|mint:Q9UI14|entrezgene/locuslink:10567(identity)	-	crc64:A5409FAF1594854C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	rogid:WS2rUY7yXRbR7pqWgfUCbnEiDbg9606	intact-crc:9C1D55AB3277C765|rigid:1nv/6BMInnXsSwk8QbyMG8XZv/s	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UJV3-2	uniprotkb:P32502	intact:EBI-10172526|ensembl:ENSP00000413976	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:q9ujv3-2(display_long)|uniprotkb:RING-type E3 ubiquitin transferase MID2(gene name synonym)|uniprotkb:FXY2(gene name synonym)|uniprotkb:Midin-2(gene name synonym)|uniprotkb:Midline defect 2(gene name synonym)|uniprotkb:Midline-2(gene name synonym)|uniprotkb:RING finger protein 60(gene name synonym)|uniprotkb:RNF60(gene name synonym)|uniprotkb:TRIM1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 1(gene name synonym)|uniprotkb:MID2(gene name)|psi-mi:MID2(display_short)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11526478|imex:IM-24995-431	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-751983(isoform-parent)|uniprotkb:Q9UJV3-2(isoform-parent)|ensembl:ENSG00000080561(gene)|ensembl:ENST00000443968(transcript)|entrezgene/locuslink:11043(identity)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	-	-	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:/FJ+V2H7SaWon7caUWkEkmHFVxQ9606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:D0C146CD8FE5D1D6|rigid:gLKZX2c9WnbLhrFzr0iSTW6taIU	false	sufficient binding region:21-705	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UJ70-2	uniprotkb:P32502	intact:EBI-11526455|ensembl:ENSP00000389087|ensembl:ENSP00000477639	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:q9uj70-2(display_long)|uniprotkb:GlcNAc kinase(gene name synonym)|uniprotkb:NAGK(gene name)|psi-mi:NAGK(display_short)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11526453|imex:IM-24995-429	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-372578(isoform-parent)|ensembl:ENSG00000124357(gene)|ensembl:ENST00000455662(transcript)|ensembl:ENST00000613852(transcript)|uniprotkb:Q9UJ70-2(isoform-parent)|entrezgene/locuslink:55577(identity)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	-	-	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:zoy4C+HK341UnmDRUlMuJucczr89606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:4C196C9D847CC887|rigid:n0pwos02ttUq0m9zwT4vZ4lEN7E	false	sufficient binding region:47-390	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32502	uniprotkb:Q9UJC3	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	intact:EBI-746704|uniprotkb:O60561|uniprotkb:Q5TG44|uniprotkb:A8MU44|uniprotkb:B4DX15|uniprotkb:A8K8E9|intact:EBI-10969618|ensembl:ENSP00000360252	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:hook1_human(display_long)|uniprotkb:HOOK1(gene name)|psi-mi:HOOK1(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11526469|imex:IM-24995-430	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	refseq:NP_056972.1|ensembl:ENSG00000134709(gene)|ensembl:ENST00000371208(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0007030"(Golgi organization)|go:"GO:0007032"(endosome organization)|go:"GO:0007040"(lysosome organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0015031"(protein transport)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0051959"(dynein light intermediate chain binding)|go:"GO:0070695"(FHF complex)|go:"GO:1905198"(manchette assembly)|go:"GO:1905719"(protein localization to perinuclear region of cytoplasm)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR008636(HOOK)|interpro:IPR036872|interpro:IPR043936|mint:Q9UJC3|entrezgene/locuslink:51361(identity)	-	crc64:A5409FAF1594854C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	rogid:QOcYbuKfnNIlNKzos5v+0+A2h3I9606	intact-crc:2DE338084C57BBDA|rigid:7kYUYjTM18DA+gT+GyTew1DPD6Y	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9Y2D8	uniprotkb:P32502	intact:EBI-2212028|uniprotkb:B4DFE3|uniprotkb:J3KR02|uniprotkb:A8K8W0|uniprotkb:D3DT13|uniprotkb:Q6P2P8|uniprotkb:Q6ULS1|uniprotkb:Q7L168|uniprotkb:Q9UIX0|intact:EBI-10964529|ensembl:ENSP00000340279	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:adip_human(display_long)|uniprotkb:SSX2IP(gene name)|psi-mi:SSX2IP(display_short)|uniprotkb:KIAA0923(gene name synonym)|uniprotkb:Afadin DIL domain-interacting protein(gene name synonym)|uniprotkb:SSX2-interacting protein(gene name synonym)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11526518|imex:IM-24995-435	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011538912.1|refseq:NP_001159765.1|refseq:NP_001159766.1|refseq:NP_001159767.1|refseq:NP_001159889.1|refseq:NP_054740.3|refseq:XP_005270484.1|refseq:XP_005270485.1|refseq:XP_006710394.1|refseq:XP_016855723.1|ensembl:ENSG00000117155(gene)|ensembl:ENST00000342203(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005912"(adherens junction)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031252"(cell leading edge)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0035735"(intraciliary transport involved in cilium assembly)|go:"GO:0036064"(ciliary basal body)|go:"GO:0060271"(cilium assembly)|go:"GO:2000145"(regulation of cell motility)|interpro:IPR021622|mint:Q9Y2D8|entrezgene/locuslink:117178(identity)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	-	-	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:E0VeMRF9SrpQKSJFP01XEbMjeF89606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:360D7DDDE17B1B1E|rigid:RUc60KIbnAdYEr1IMFPesdm94Xs	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32502	uniprotkb:Q9UJX2	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	intact:EBI-396137|uniprotkb:O75433|uniprotkb:Q9BS73|uniprotkb:B4E3A2|uniprotkb:B7WP05|uniprotkb:Q53FN2|uniprotkb:A8K6E5|uniprotkb:D3DQB7|ensembl:ENSP00000378350	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:cdc23_human(display_long)|uniprotkb:CDC23(gene name)|psi-mi:CDC23(display_short)|uniprotkb:ANAPC8(gene name synonym)|uniprotkb:Anaphase-promoting complex subunit 8(gene name synonym)|uniprotkb:Cyclosome subunit 8(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11526489|imex:IM-24995-432	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	refseq:NP_004652.2|dip:DIP-32959N|ensembl:ENSG00000094880(gene)|ensembl:ENST00000394886(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0007091"(metaphase/anaphase transition of mitotic cell cycle)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030071"(regulation of mitotic metaphase/anaphase transition)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0051301"(cell division)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR007192(Cdc23)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|mint:Q9UJX2|rcsb pdb:4UI9|rcsb pdb:5A31|rcsb pdb:5G04|rcsb pdb:5G05|rcsb pdb:5KHR|rcsb pdb:5KHU|rcsb pdb:5L9T|rcsb pdb:5L9U|rcsb pdb:5LCW|rcsb pdb:6Q6G|rcsb pdb:6Q6H|rcsb pdb:6TLJ|rcsb pdb:6TM5|rcsb pdb:6TNT|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-9687136|reactome:R-HSA-983168|entrezgene/locuslink:8697(identity)	-	crc64:A5409FAF1594854C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	rogid:uTZL2UHzZHLoKnio/1LcuSzZpW09606	intact-crc:071F4324760F53A5|rigid:oByXm7mip5OSH18LrnwpeWvZn+U	false	-	sufficient binding region:7-597	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UNE7	uniprotkb:P32502	intact:EBI-357085|uniprotkb:O60526|uniprotkb:Q969U2|uniprotkb:Q9HBT1|uniprotkb:A2IDB9|ensembl:ENSP00000219548	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:chip_human(display_long)|uniprotkb:CHIP(gene name synonym)|uniprotkb:STUB1(gene name)|psi-mi:STUB1(display_short)|uniprotkb:PP1131(orf name)|uniprotkb:Carboxy terminus of Hsp70-interacting protein(gene name synonym)|uniprotkb:STIP1 homology and U box-containing protein 1(gene name synonym)|uniprotkb:CLL-associated antigen KW-8(gene name synonym)|uniprotkb:Antigen NY-CO-7(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase CHIP(gene name synonym)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11526500|imex:IM-24995-433	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-29752N|refseq:NP_005852.2|refseq:NP_001280126.1|ensembl:ENSG00000103266(gene)|ensembl:ENST00000219548(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0002931"(response to ischemia)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030911"(TPR domain binding)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031371"(ubiquitin conjugating enzyme complex)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031943"(regulation of glucocorticoid metabolic process)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|go:"GO:0034605"(cellular response to heat)|go:"GO:0038128"(ERBB2 signaling pathway)|go:"GO:0042405"(nuclear inclusion body)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0046332"(SMAD binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0051604"(protein maturation)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0030579"(ubiquitin-dependent SMAD protein catabolic process)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061684"(chaperone-mediated autophagy)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0071218"(cellular response to misfolded protein)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0090035"(positive regulation of chaperone-mediated protein complex assembly)|go:"GO:0101031"(chaperone complex)|interpro:IPR003613(U box)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019734|interpro:IPR041312|mint:Q9UNE7|rcsb pdb:4KBQ|rcsb pdb:6EFK|rcsb pdb:6NSV|reactome:R-HSA-2173788|reactome:R-HSA-5213460|reactome:R-HSA-5675482|reactome:R-HSA-8863795|reactome:R-HSA-8939902|reactome:R-HSA-8948751|reactome:R-HSA-983168|entrezgene/locuslink:10273(identity)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	-	-	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:h4QyIM0TptgkQppPUgiKn68XjP49606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:F08B522C3E22A17F|rigid:zTTDiLY+4UF0EULVlTU2BY5Jh4s	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32502	uniprotkb:Q9UPY8	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	intact:EBI-726739|uniprotkb:O00265|uniprotkb:Q6FI15|uniprotkb:Q9BZP7|uniprotkb:Q9BZP8|uniprotkb:B7WPK5|uniprotkb:Q6FHB0|ensembl:ENSP00000233121	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:mare3_human(display_long)|uniprotkb:End-binding protein 3(gene name synonym)|uniprotkb:EB1 protein family member 3(gene name synonym)|uniprotkb:RP3(gene name synonym)|uniprotkb:MAPRE3(gene name)|psi-mi:MAPRE3(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11526509|imex:IM-24995-434	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	refseq:NP_036458.2|refseq:XP_016859086.1|refseq:NP_001289979.1|refseq:XP_006712030.1|refseq:XP_011531002.1|dip:DIP-56069N|ensembl:ENSG00000084764(gene)|ensembl:ENST00000233121(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0008017"(microtubule binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030496"(midbody)|go:"GO:0031110"(regulation of microtubule polymerization or depolymerization)|go:"GO:0031113"(regulation of microtubule polymerization)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0042802"(identical protein binding)|go:"GO:0045737"(positive regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051233"(spindle midzone)|go:"GO:0051301"(cell division)|go:"GO:1903033"(positive regulation of microtubule plus-end binding)|go:"GO:1904825"(protein localization to microtubule plus-end)|go:"GO:1905721"(mitotic spindle astral microtubule end)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR004953(EB1, C-terminal)|interpro:IPR027328|interpro:IPR027738|interpro:IPR036133|interpro:IPR036872|mint:Q9UPY8|rcsb pdb:1WYO|rcsb pdb:3CO1|rcsb pdb:3JAK|rcsb pdb:3JAL|rcsb pdb:3JAR|rcsb pdb:3TQ7|entrezgene/locuslink:22924(identity)	-	crc64:A5409FAF1594854C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	rogid:LHuufxyNrygS3iFW5mmg13R43NE9606	intact-crc:0EF91735242650DC|rigid:pcUI+ZAYoWEoUxXaEdL9Ti4WkEA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38159	uniprotkb:P32505	intact:EBI-743526|ensembl:ENSP00000359645|uniprotkb:Q5JQ67|uniprotkb:Q969R3|uniprotkb:D3DWH0|uniprotkb:E9PG86|uniprotkb:Q8N8Y7|uniprotkb:B4E3U4	intact:EBI-11770|ensemblfungi:YGL122C|uniprotkb:D6VU26	psi-mi:rbmx_human(display_long)|uniprotkb:Glycoprotein p43(gene name synonym)|uniprotkb:RBMX(gene name)|psi-mi:RBMX(display_short)|uniprotkb:HNRPG(gene name synonym)|uniprotkb:RBMXP1(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein G(gene name synonym)	psi-mi:nab2_yeast(display_long)|uniprotkb:YGL122C(locus name)|uniprotkb:NAB2(gene name)|psi-mi:NAB2(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11526546|imex:IM-24995-438	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000147274(gene)|ensembl:ENST00000320676(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000791"(euchromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0044530"(supraspliceosomal complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0006509"(membrane protein ectodomain proteolysis)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012604(RBM1CTR)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|mint:P38159|rcsb pdb:2MB0|rcsb pdb:2MKS|reactome:R-HSA-72163|reactome:R-HSA-72203|reactome:R-HSA-9013418|reactome:R-HSA-9013422|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273|refseq:NP_002130.2|refseq:NP_001158275.1|dip:DIP-34447N|entrezgene/locuslink:27316(identity)	ensemblfungi:YGL122C(gene)|ensemblfungi:YGL122C_mRNA(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0008097"(5S rRNA binding)|go:"GO:0008143"("poly(A) binding")|go:"GO:0008312"(7S RNA binding)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0033204"(ribonuclease P RNA binding)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0046872"(metal ion binding)|go:"GO:1900152"(negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|interpro:IPR021083|interpro:IPR040366|go:"GO:0045945"(positive regulation of transcription by RNA polymerase III)|interpro:IPR041044|interpro:IPR043094|rcsb pdb:2JPS|rcsb pdb:2LHN|rcsb pdb:2V75|rcsb pdb:3LCN|rcsb pdb:3ZJ1|rcsb pdb:3ZJ2|rcsb pdb:4JLQ|rcsb pdb:5L2L|refseq:NP_011393.3|sgd:S000003090|mint:P32505|dip:DIP-1331N|sgd:YGL122C(identity)	-	-	crc64:40335C3D4658DD91	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:ocCkdy9PxjeVLUQf0tMVCEhFfO89606	rogid:tNdhCVVTRYjqg7BES5wD2Gg4rjw559292	intact-crc:EE5F858DA5D5D67C|rigid:OHmVTY27Tx1ptByqU/vkxddfBgc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32502	uniprotkb:Q9Y3Q8	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	intact:EBI-739485|uniprotkb:A8MWR6|ensembl:ENSP00000300181|uniprotkb:A4D2C3|uniprotkb:D6W5V9	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:t22d4_human(display_long)|uniprotkb:TSC22D4(gene name)|psi-mi:TSC22D4(display_short)|uniprotkb:TILZ2(gene name synonym)|uniprotkb:TSC22-related-inducible leucine zipper protein 2(gene name synonym)|uniprotkb:Tsc-22-like protein THG-1(gene name synonym)|uniprotkb:THG1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11526527|imex:IM-24995-436	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	ensembl:ENSG00000166925(gene)|ensembl:ENST00000300181(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006970"(response to osmotic stress)|interpro:IPR000580(TSC-22 / Dip / Bun)|interpro:IPR042553|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|refseq:NP_112197.1|refseq:NP_001289972.1|entrezgene/locuslink:81628(identity)	-	crc64:A5409FAF1594854C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	rogid:eL12cHY76zEPOXzT1HFKPSckS8Y9606	intact-crc:853F5C98EC665EDA|rigid:Di+XqheOggbNvebETiEmKrLRyVg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9Y6D9	uniprotkb:P32502	intact:EBI-742610|uniprotkb:B3KR41|uniprotkb:Q9UNH0|uniprotkb:Q13312|uniprotkb:Q75MI0|uniprotkb:Q86UM4|ensembl:ENSP00000265854|ensembl:ENSP00000382562|ensembl:ENSP00000385334	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:md1l1_human(display_long)|uniprotkb:Mitotic arrest deficient 1-like protein 1(gene name synonym)|uniprotkb:Mitotic checkpoint MAD1 protein homolog(gene name synonym)|uniprotkb:Tax-binding protein 181(gene name synonym)|uniprotkb:MAD1L1(gene name)|psi-mi:MAD1L1(display_short)|uniprotkb:MAD1(gene name synonym)|uniprotkb:TXBP181(gene name synonym)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11526537|imex:IM-24995-437	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001013858.1|refseq:NP_001013859.1|refseq:NP_003541.2|refseq:NP_001291452.1|refseq:NP_001291453.1|ensembl:ENSG00000002822(gene)|ensembl:ENST00000265854(transcript)|go:"GO:0090235"(regulation of metaphase plate congression)|go:"GO:1902426"(deactivation of mitotic spindle assembly checkpoint)|interpro:IPR008672(Mitotic checkpoint)|mint:Q9Y6D9|rcsb pdb:1GO4|rcsb pdb:4DZO|rcsb pdb:7B1F|rcsb pdb:7B1H|rcsb pdb:7B1J|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|ensembl:ENST00000399654(transcript)|ensembl:ENST00000406869(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043515"(kinetochore binding)|go:"GO:0044615"(nuclear pore nuclear basket)|go:"GO:0048538"(thymus development)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0072686"(mitotic spindle)|refseq:XP_005249934.1|dip:DIP-29654N|entrezgene/locuslink:8379(identity)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	-	-	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:9CcqpZlN0IgqC939rIo7vNgOvLQ9606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:9E98B79554D70E86|rigid:i1ztDpU8PgAzP0pVDv/71CBfv5k	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q13422-7	uniprotkb:P32529	intact:EBI-11522367|ensembl:ENSP00000352123|ensembl:ENSP00000413025	intact:EBI-15756|uniprotkb:D6VWN4|ensemblfungi:YJR063W	psi-mi:q13422-7(display_long)|uniprotkb:IKZF1(gene name)|psi-mi:IKZF1(display_short)|uniprotkb:IK1(gene name synonym)|uniprotkb:IKAROS(gene name synonym)|uniprotkb:Ikaros family zinc finger protein 1(gene name synonym)|uniprotkb:LYF1(gene name synonym)|uniprotkb:Lymphoid transcription factor LyF-1(gene name synonym)|uniprotkb:ZNFN1A1(gene name synonym)	psi-mi:rpa12_yeast(display_long)|uniprotkb:RPA12(gene name)|psi-mi:RPA12(display_short)|uniprotkb:RRN4(gene name synonym)|uniprotkb:YJR063W(locus name)|uniprotkb:J1747(orf name)|uniprotkb:DNA-directed RNA polymerase I 13.7 kDa polypeptide(gene name synonym)|uniprotkb:A12(gene name synonym)|uniprotkb:A12.2(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11526581|imex:IM-24995-441	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-745305(isoform-parent)|ensembl:ENSG00000185811(gene)|ensembl:ENST00000359197(transcript)|ensembl:ENST00000439701(transcript)|uniprotkb:Q13422-7(isoform-parent)|entrezgene/locuslink:10320(identity)	refseq:NP_012597.1|sgd:S000003824|dip:DIP-236N|mint:P32529|ensemblfungi:YJR063W(gene)|ensemblfungi:YJR063W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001054"(RNA polymerase I activity)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006363"(termination of RNA polymerase I transcription)|go:"GO:0006379"(mRNA cleavage)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042790"(nucleolar large rRNA transcription by RNA polymerase I)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR001222(Zinc finger, TFIIS-type)|interpro:IPR001529(DNA-directed RNA polymerase, M/15 kDa subunit)|interpro:IPR012164(DNA-directed RNA polymerase, subunit C11/M/9)|interpro:IPR019761|interpro:IPR034004|rcsb pdb:4C2M|rcsb pdb:4C3H|rcsb pdb:4C3I|rcsb pdb:4C3J|rcsb pdb:4YM7|rcsb pdb:5G5L|rcsb pdb:5LMX|rcsb pdb:5M3F|rcsb pdb:5M3M|rcsb pdb:5M5W|rcsb pdb:5M5X|rcsb pdb:5M5Y|rcsb pdb:5M64|rcsb pdb:5N5Y|rcsb pdb:5N5Z|rcsb pdb:5N60|rcsb pdb:5N61|rcsb pdb:5OA1|rcsb pdb:5W5Y|rcsb pdb:5W64|rcsb pdb:5W65|rcsb pdb:5W66|rcsb pdb:6H67|rcsb pdb:6H68|rcsb pdb:6HKO|rcsb pdb:6HLQ|rcsb pdb:6HLR|rcsb pdb:6HLS|rcsb pdb:6RQH|rcsb pdb:6RQL|rcsb pdb:6RQT|rcsb pdb:6RRD|rcsb pdb:6RUI|rcsb pdb:6RUO|rcsb pdb:6RWE|rcsb pdb:6TPS|reactome:R-SCE-73762|reactome:R-SCE-73772|sgd:YJR063W(identity)	-	-	crc64:D79372070819987C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:ou/ovXYoMneBNVp4pj38VxenfyY9606	rogid:B0Zmf643W8DtAQteaDk8PVvdqW4559292	intact-crc:9300AB19F0C080A9|rigid:OkVugayMDgkvP4sET1tDl42XLrc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q86SE5-3	uniprotkb:P32505	intact:EBI-11526555|ensembl:ENSP00000430128	intact:EBI-11770|ensemblfungi:YGL122C|uniprotkb:D6VU26	psi-mi:q86se5-3(display_long)|uniprotkb:RALYL(gene name)|psi-mi:RALYL(display_short)|uniprotkb:HNRPCL3(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein C-like 3(gene name synonym)	psi-mi:nab2_yeast(display_long)|uniprotkb:YGL122C(locus name)|uniprotkb:NAB2(gene name)|psi-mi:NAB2(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11526559|imex:IM-24995-439	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000184672(gene)|ensembl:ENST00000517638(transcript)|intact:EBI-741520(isoform-parent)|uniprotkb:Q86SE5-3(isoform-parent)|entrezgene/locuslink:138046(identity)	ensemblfungi:YGL122C(gene)|ensemblfungi:YGL122C_mRNA(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0008097"(5S rRNA binding)|go:"GO:0008143"("poly(A) binding")|go:"GO:0008312"(7S RNA binding)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0033204"(ribonuclease P RNA binding)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0046872"(metal ion binding)|go:"GO:1900152"(negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|interpro:IPR021083|interpro:IPR040366|go:"GO:0045945"(positive regulation of transcription by RNA polymerase III)|interpro:IPR041044|interpro:IPR043094|rcsb pdb:2JPS|rcsb pdb:2LHN|rcsb pdb:2V75|rcsb pdb:3LCN|rcsb pdb:3ZJ1|rcsb pdb:3ZJ2|rcsb pdb:4JLQ|rcsb pdb:5L2L|refseq:NP_011393.3|sgd:S000003090|mint:P32505|dip:DIP-1331N|sgd:YGL122C(identity)	-	isoform-comment:No experimental confirmation available.	crc64:40335C3D4658DD91	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:7Vx29NJ3c8JBc76fGQWhrrQ9Stg9606	rogid:tNdhCVVTRYjqg7BES5wD2Gg4rjw559292	intact-crc:CBD901AB84761C80|rigid:qh+Ucdp9I+wW4n5ydm5yk/WsF0c	false	sufficient binding region:14-304	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32529	uniprotkb:Q08379	intact:EBI-15756|uniprotkb:D6VWN4|ensemblfungi:YJR063W	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	psi-mi:rpa12_yeast(display_long)|uniprotkb:RPA12(gene name)|psi-mi:RPA12(display_short)|uniprotkb:RRN4(gene name synonym)|uniprotkb:YJR063W(locus name)|uniprotkb:J1747(orf name)|uniprotkb:DNA-directed RNA polymerase I 13.7 kDa polypeptide(gene name synonym)|uniprotkb:A12(gene name synonym)|uniprotkb:A12.2(gene name synonym)	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11526570|imex:IM-24995-440	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012597.1|sgd:S000003824|dip:DIP-236N|mint:P32529|ensemblfungi:YJR063W(gene)|ensemblfungi:YJR063W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001054"(RNA polymerase I activity)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006363"(termination of RNA polymerase I transcription)|go:"GO:0006379"(mRNA cleavage)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042790"(nucleolar large rRNA transcription by RNA polymerase I)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR001222(Zinc finger, TFIIS-type)|interpro:IPR001529(DNA-directed RNA polymerase, M/15 kDa subunit)|interpro:IPR012164(DNA-directed RNA polymerase, subunit C11/M/9)|interpro:IPR019761|interpro:IPR034004|rcsb pdb:4C2M|rcsb pdb:4C3H|rcsb pdb:4C3I|rcsb pdb:4C3J|rcsb pdb:4YM7|rcsb pdb:5G5L|rcsb pdb:5LMX|rcsb pdb:5M3F|rcsb pdb:5M3M|rcsb pdb:5M5W|rcsb pdb:5M5X|rcsb pdb:5M5Y|rcsb pdb:5M64|rcsb pdb:5N5Y|rcsb pdb:5N5Z|rcsb pdb:5N60|rcsb pdb:5N61|rcsb pdb:5OA1|rcsb pdb:5W5Y|rcsb pdb:5W64|rcsb pdb:5W65|rcsb pdb:5W66|rcsb pdb:6H67|rcsb pdb:6H68|rcsb pdb:6HKO|rcsb pdb:6HLQ|rcsb pdb:6HLR|rcsb pdb:6HLS|rcsb pdb:6RQH|rcsb pdb:6RQL|rcsb pdb:6RQT|rcsb pdb:6RRD|rcsb pdb:6RUI|rcsb pdb:6RUO|rcsb pdb:6RWE|rcsb pdb:6TPS|reactome:R-SCE-73762|reactome:R-SCE-73772|sgd:YJR063W(identity)	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N|entrezgene/locuslink:2801(identity)	-	crc64:D79372070819987C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2017/05/26	rogid:B0Zmf643W8DtAQteaDk8PVvdqW4559292	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	intact-crc:386F803BF0D1209C|rigid:iRbmEMepCZ591rpMbFdcN5GsJBU	false	-	sufficient binding region:383-1002	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q13422-7	uniprotkb:P32562	intact:EBI-11522367|ensembl:ENSP00000352123|ensembl:ENSP00000413025	intact:EBI-4440|ensemblfungi:YMR001C|uniprotkb:D6VZH5	psi-mi:q13422-7(display_long)|uniprotkb:IKZF1(gene name)|psi-mi:IKZF1(display_short)|uniprotkb:IK1(gene name synonym)|uniprotkb:IKAROS(gene name synonym)|uniprotkb:Ikaros family zinc finger protein 1(gene name synonym)|uniprotkb:LYF1(gene name synonym)|uniprotkb:Lymphoid transcription factor LyF-1(gene name synonym)|uniprotkb:ZNFN1A1(gene name synonym)	psi-mi:cdc5_yeast(display_long)|uniprotkb:CDC5(gene name)|psi-mi:CDC5(display_short)|uniprotkb:MSD2(gene name synonym)|uniprotkb:PKX2(gene name synonym)|uniprotkb:YMR001C(locus name)|uniprotkb:YM8270.03C(orf name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11526614|imex:IM-24995-444	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-745305(isoform-parent)|ensembl:ENSG00000185811(gene)|ensembl:ENST00000359197(transcript)|ensembl:ENST00000439701(transcript)|uniprotkb:Q13422-7(isoform-parent)|entrezgene/locuslink:10320(identity)	ensemblfungi:YMR001C(gene)|ensemblfungi:YMR001C_mRNA(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0000922"(spindle pole)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0010458"(exit from mitosis)|go:"GO:0010696"(positive regulation of mitotic spindle pole body separation)|go:"GO:0019237"(centromeric DNA binding)|refseq:NP_013714.1|sgd:S000004603|reactome:R-SCE-6804115|reactome:R-SCE-156711|reactome:R-SCE-162658|reactome:R-SCE-2565942|dip:DIP-2321N|reactome:R-SCE-2500257|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0035025"(positive regulation of Rho protein signal transduction)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051301"(cell division)|go:"GO:0070194"(synaptonemal complex disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0110083"(positive regulation of protein localization to cell division site involved in mitotic actomyosin contractile ring assembly)|go:"GO:1902542"(regulation of protein localization to mitotic spindle pole body)|go:"GO:1903353"(regulation of nucleus organization)|go:"GO:1904750"(negative regulation of protein localization to nucleolus)|go:"GO:1905339"(positive regulation of cohesin unloading)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033695|interpro:IPR033701|interpro:IPR036947|rcsb pdb:6MF4|rcsb pdb:6MF5|rcsb pdb:6MF6|sgd:YMR001C(identity)	-	-	crc64:B5A25F1BBBEAA3DC	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:ou/ovXYoMneBNVp4pj38VxenfyY9606	rogid:XXSkltYvBA9Zkh0Kr5s1znazUC0559292	intact-crc:8EA1512E9DDC656C|rigid:HDP6+0UygbB4Z+9FmY++33zoPyc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P14859-6	uniprotkb:P32562	intact:EBI-11526590|ensembl:ENSP00000356840	intact:EBI-4440|ensemblfungi:YMR001C|uniprotkb:D6VZH5	psi-mi:p14859-6(display_long)|uniprotkb:NF-A1(gene name synonym)|uniprotkb:OCT1(gene name synonym)|uniprotkb:OTF1(gene name synonym)|uniprotkb:Octamer-binding protein 1(gene name synonym)|uniprotkb:Octamer-binding transcription factor 1(gene name synonym)|uniprotkb:POU2F1(gene name)|psi-mi:POU2F1(display_short)	psi-mi:cdc5_yeast(display_long)|uniprotkb:CDC5(gene name)|psi-mi:CDC5(display_short)|uniprotkb:MSD2(gene name synonym)|uniprotkb:PKX2(gene name synonym)|uniprotkb:YMR001C(locus name)|uniprotkb:YM8270.03C(orf name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11526594|imex:IM-24995-442	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000143190(gene)|ensembl:ENST00000367866(transcript)|intact:EBI-624770(isoform-parent)|uniprotkb:P14859-6(isoform-parent)|entrezgene/locuslink:5451(identity)	ensemblfungi:YMR001C(gene)|ensemblfungi:YMR001C_mRNA(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0000922"(spindle pole)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0010458"(exit from mitosis)|go:"GO:0010696"(positive regulation of mitotic spindle pole body separation)|go:"GO:0019237"(centromeric DNA binding)|refseq:NP_013714.1|sgd:S000004603|reactome:R-SCE-6804115|reactome:R-SCE-156711|reactome:R-SCE-162658|reactome:R-SCE-2565942|dip:DIP-2321N|reactome:R-SCE-2500257|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0035025"(positive regulation of Rho protein signal transduction)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051301"(cell division)|go:"GO:0070194"(synaptonemal complex disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0110083"(positive regulation of protein localization to cell division site involved in mitotic actomyosin contractile ring assembly)|go:"GO:1902542"(regulation of protein localization to mitotic spindle pole body)|go:"GO:1903353"(regulation of nucleus organization)|go:"GO:1904750"(negative regulation of protein localization to nucleolus)|go:"GO:1905339"(positive regulation of cohesin unloading)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033695|interpro:IPR033701|interpro:IPR036947|rcsb pdb:6MF4|rcsb pdb:6MF5|rcsb pdb:6MF6|sgd:YMR001C(identity)	-	isoform-comment:No experimental confirmation available.	crc64:B5A25F1BBBEAA3DC	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:jKwhpG5wRMncTZjM6bNUCL0CPqQ9606	rogid:XXSkltYvBA9Zkh0Kr5s1znazUC0559292	intact-crc:078257C37C55F872|rigid:pKDK+p9Bd/jFaUKhj9be5X4eW2g	false	sufficient binding region:24-766	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P63279	uniprotkb:P32562	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	intact:EBI-4440|ensemblfungi:YMR001C|uniprotkb:D6VZH5	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:cdc5_yeast(display_long)|uniprotkb:CDC5(gene name)|psi-mi:CDC5(display_short)|uniprotkb:MSD2(gene name synonym)|uniprotkb:PKX2(gene name synonym)|uniprotkb:YMR001C(locus name)|uniprotkb:YM8270.03C(orf name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11526605|imex:IM-24995-443	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N|entrezgene/locuslink:7329(identity)	ensemblfungi:YMR001C(gene)|ensemblfungi:YMR001C_mRNA(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0000922"(spindle pole)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0010458"(exit from mitosis)|go:"GO:0010696"(positive regulation of mitotic spindle pole body separation)|go:"GO:0019237"(centromeric DNA binding)|refseq:NP_013714.1|sgd:S000004603|reactome:R-SCE-6804115|reactome:R-SCE-156711|reactome:R-SCE-162658|reactome:R-SCE-2565942|dip:DIP-2321N|reactome:R-SCE-2500257|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0035025"(positive regulation of Rho protein signal transduction)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051301"(cell division)|go:"GO:0070194"(synaptonemal complex disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0110083"(positive regulation of protein localization to cell division site involved in mitotic actomyosin contractile ring assembly)|go:"GO:1902542"(regulation of protein localization to mitotic spindle pole body)|go:"GO:1903353"(regulation of nucleus organization)|go:"GO:1904750"(negative regulation of protein localization to nucleolus)|go:"GO:1905339"(positive regulation of cohesin unloading)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033695|interpro:IPR033701|interpro:IPR036947|rcsb pdb:6MF4|rcsb pdb:6MF5|rcsb pdb:6MF6|sgd:YMR001C(identity)	-	-	crc64:B5A25F1BBBEAA3DC	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	rogid:XXSkltYvBA9Zkh0Kr5s1znazUC0559292	intact-crc:1907B641BFD6AC78|rigid:ko/lk8jigrCH06sKQuyEbR2AXj4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O94972	uniprotkb:P32571	intact:EBI-741602|uniprotkb:Q7Z3E6|uniprotkb:Q8IYF7|uniprotkb:Q8WYF7|intact:EBI-28976055|ensembl:ENSP00000262294|ensembl:ENSP00000376785|uniprotkb:A8K0V9|uniprotkb:A8K8U4|uniprotkb:A8MZ79|uniprotkb:B4DGZ3|uniprotkb:F8WEE6	intact:EBI-19840|uniprotkb:D6VS55|ensemblfungi:YDR069C	psi-mi:tri37_human(display_long)|uniprotkb:Mulibrey nanism protein(gene name synonym)|uniprotkb:TRIM37(gene name)|psi-mi:TRIM37(display_short)|uniprotkb:KIAA0898(gene name synonym)|uniprotkb:MUL(gene name synonym)|uniprotkb:POB1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 37(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM37(gene name synonym)	psi-mi:ubp4_yeast(display_long)|uniprotkb:DOA4(gene name)|psi-mi:DOA4(display_short)|uniprotkb:MUT4(gene name synonym)|uniprotkb:SSV7(gene name synonym)|uniprotkb:YDR069C(locus name)|uniprotkb:YD9609.23C(orf name)|uniprotkb:YD8554.02C(orf name)|uniprotkb:D4270(orf name)|uniprotkb:NPI2(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 4(gene name synonym)|uniprotkb:Deubiquitinating enzyme 4(gene name synonym)|uniprotkb:Vacuole biogenesis protein SSV7(gene name synonym)|uniprotkb:Ubiquitin thioesterase 4(gene name synonym)|uniprotkb:DOS1(gene name synonym)|uniprotkb:UBP4(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11526650|imex:IM-24995-448	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001005207.1|refseq:NP_056109.1|refseq:NP_001307916.1|ensembl:ENSP00000262294|ensembl:ENST00000393065|ensembl:ENSP00000376784|ensembl:ENSP00000376785|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046600"(negative regulation of centriole replication)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070842"(aggresome assembly)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002083(MATH)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR008974(TRAF-like)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR037299|rcsb pdb:3LRQ|reactome:R-HSA-983168|ensembl:ENSG00000108395(gene)|ensembl:ENST00000262294(transcript)|ensembl:ENST00000393066(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005777"(peroxisome)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016235"(aggresome)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0035518"(histone H2A monoubiquitination)|refseq:NP_001307919.1|dip:DIP-34437N|entrezgene/locuslink:4591(identity)	sgd:S000002476|ensemblfungi:YDR069C(gene)|ensemblfungi:YDR069C_mRNA(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005739"(mitochondrion)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0010992"(ubiquitin recycling)|go:"GO:0010995"(free ubiquitin chain depolymerization)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0031902"(late endosome membrane)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0070676"(intralumenal vesicle formation)|go:"GO:1904669"(ATP export)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR001763(Rhodanese-like)|interpro:IPR018200|interpro:IPR028889|interpro:IPR036873|interpro:IPR038765|refseq:NP_010354.3|dip:DIP-5298N|mint:P32571|sgd:YDR069C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:y2njeO0MUBrKU9MUvkbo1uZmqkE9606	rogid:UTBSWmpygyxo1ygxp/sQ8wgqnMo559292	intact-crc:5DE8A0EB87D6D3DC|rigid:Fip2dzLdN2rSbGgYxEH7/vyk+oU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q7L5A3	uniprotkb:P32562	intact:EBI-745689|uniprotkb:O60377|uniprotkb:Q9BQ60|uniprotkb:Q9HAI9|uniprotkb:Q9P1Y9|ensembl:ENSP00000319897|ensembl:ENSP00000367819|ensembl:ENSP00000367823|ensembl:ENSP00000474335|ensembl:ENSP00000474833|ensembl:ENSP00000475120|uniprotkb:D3DRN5|uniprotkb:B1AML4|uniprotkb:B1AML5	intact:EBI-4440|ensemblfungi:YMR001C|uniprotkb:D6VZH5	psi-mi:f214b_human(display_long)|uniprotkb:FAM214B(gene name)|psi-mi:FAM214B(display_short)|uniprotkb:KIAA1539(gene name synonym)	psi-mi:cdc5_yeast(display_long)|uniprotkb:CDC5(gene name)|psi-mi:CDC5(display_short)|uniprotkb:MSD2(gene name synonym)|uniprotkb:PKX2(gene name synonym)|uniprotkb:YMR001C(locus name)|uniprotkb:YM8270.03C(orf name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11526623|imex:IM-24995-445	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_079458.2|refseq:XP_011516339.1|refseq:XP_011516345.1|refseq:XP_011516346.1|ensembl:ENST00000603301(transcript)|ensembl:ENST00000605244(transcript)|go:"GO:0005634"(nucleus)|interpro:IPR025261|interpro:IPR033473|mint:Q7L5A3|ensembl:ENSG00000005238(gene)|ensembl:ENST00000322813(transcript)|ensembl:ENST00000378557(transcript)|ensembl:ENST00000378561(transcript)|ensembl:ENST00000488109(transcript)|refseq:NP_001304920.1|refseq:XP_005251645.1|refseq:XP_005251647.1|refseq:XP_005251648.1|refseq:XP_016870659.1|entrezgene/locuslink:80256(identity)	ensemblfungi:YMR001C(gene)|ensemblfungi:YMR001C_mRNA(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0000922"(spindle pole)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0010458"(exit from mitosis)|go:"GO:0010696"(positive regulation of mitotic spindle pole body separation)|go:"GO:0019237"(centromeric DNA binding)|refseq:NP_013714.1|sgd:S000004603|reactome:R-SCE-6804115|reactome:R-SCE-156711|reactome:R-SCE-162658|reactome:R-SCE-2565942|dip:DIP-2321N|reactome:R-SCE-2500257|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0035025"(positive regulation of Rho protein signal transduction)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051301"(cell division)|go:"GO:0070194"(synaptonemal complex disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0110083"(positive regulation of protein localization to cell division site involved in mitotic actomyosin contractile ring assembly)|go:"GO:1902542"(regulation of protein localization to mitotic spindle pole body)|go:"GO:1903353"(regulation of nucleus organization)|go:"GO:1904750"(negative regulation of protein localization to nucleolus)|go:"GO:1905339"(positive regulation of cohesin unloading)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033695|interpro:IPR033701|interpro:IPR036947|rcsb pdb:6MF4|rcsb pdb:6MF5|rcsb pdb:6MF6|sgd:YMR001C(identity)	-	-	crc64:B5A25F1BBBEAA3DC	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:M9Hjv238OhxmmyVQbKrX6JOYL7k9606	rogid:XXSkltYvBA9Zkh0Kr5s1znazUC0559292	intact-crc:279DE527DB002264|rigid:6bX+YSG9XqF0QTwLWHdgCismuoA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32562	uniprotkb:Q96M27	intact:EBI-4440|ensemblfungi:YMR001C|uniprotkb:D6VZH5	intact:EBI-2560879|intact:EBI-28987821|uniprotkb:Q8NEZ7|uniprotkb:Q86Y42|uniprotkb:Q69YM8|uniprotkb:Q7L2U7|uniprotkb:Q96AJ3|uniprotkb:Q8IVL4|uniprotkb:Q8IVJ4|ensembl:ENSP00000296666	psi-mi:cdc5_yeast(display_long)|uniprotkb:CDC5(gene name)|psi-mi:CDC5(display_short)|uniprotkb:MSD2(gene name synonym)|uniprotkb:PKX2(gene name synonym)|uniprotkb:YMR001C(locus name)|uniprotkb:YM8270.03C(orf name)	psi-mi:prrc1_human(display_long)|uniprotkb:PRRC1(gene name)|psi-mi:PRRC1(display_short)|uniprotkb:Proline-rich and coiled-coil-containing protein 1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11526632|imex:IM-24995-446	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YMR001C(gene)|ensemblfungi:YMR001C_mRNA(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0000922"(spindle pole)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0010458"(exit from mitosis)|go:"GO:0010696"(positive regulation of mitotic spindle pole body separation)|go:"GO:0019237"(centromeric DNA binding)|refseq:NP_013714.1|sgd:S000004603|reactome:R-SCE-6804115|reactome:R-SCE-156711|reactome:R-SCE-162658|reactome:R-SCE-2565942|dip:DIP-2321N|reactome:R-SCE-2500257|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0035025"(positive regulation of Rho protein signal transduction)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051301"(cell division)|go:"GO:0070194"(synaptonemal complex disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0110083"(positive regulation of protein localization to cell division site involved in mitotic actomyosin contractile ring assembly)|go:"GO:1902542"(regulation of protein localization to mitotic spindle pole body)|go:"GO:1903353"(regulation of nucleus organization)|go:"GO:1904750"(negative regulation of protein localization to nucleolus)|go:"GO:1905339"(positive regulation of cohesin unloading)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033695|interpro:IPR033701|interpro:IPR036947|rcsb pdb:6MF4|rcsb pdb:6MF5|rcsb pdb:6MF6|sgd:YMR001C(identity)	refseq:NP_570721.1|refseq:NP_001273737.1|ensembl:ENSP00000296666|ensembl:ENST00000442138|ensembl:ENSP00000392873|ensembl:ENST00000512635|ensembl:ENSP00000421965|refseq:XP_006714592.1|ensembl:ENSG00000164244(gene)|ensembl:ENST00000296666(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0034199"(activation of protein kinase A activity)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|interpro:IPR026533|interpro:IPR026534|interpro:IPR029001|mint:Q96M27|entrezgene/locuslink:133619(identity)	-	crc64:B5A25F1BBBEAA3DC	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:XXSkltYvBA9Zkh0Kr5s1znazUC0559292	rogid:PLR9r6Zo0BDrdOArwQjuDiVPIik9606	intact-crc:15A965FCD5CDB1B1|rigid:VWvzr7qeIgW0D1wCs3qAY4B3Ng8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
intact:EBI-11523568	uniprotkb:P32571	-	intact:EBI-19840|uniprotkb:D6VS55|ensemblfungi:YDR069C	psi-mi:nav2(display_short)|psi-mi:EBI-11523568(display_long)	psi-mi:ubp4_yeast(display_long)|uniprotkb:DOA4(gene name)|psi-mi:DOA4(display_short)|uniprotkb:MUT4(gene name synonym)|uniprotkb:SSV7(gene name synonym)|uniprotkb:YDR069C(locus name)|uniprotkb:YD9609.23C(orf name)|uniprotkb:YD8554.02C(orf name)|uniprotkb:D4270(orf name)|uniprotkb:NPI2(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 4(gene name synonym)|uniprotkb:Deubiquitinating enzyme 4(gene name synonym)|uniprotkb:Vacuole biogenesis protein SSV7(gene name synonym)|uniprotkb:Ubiquitin thioesterase 4(gene name synonym)|uniprotkb:DOS1(gene name synonym)|uniprotkb:UBP4(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11526641|imex:IM-24995-447	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	entrezgene/locuslink:89797(identity)	sgd:S000002476|ensemblfungi:YDR069C(gene)|ensemblfungi:YDR069C_mRNA(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005739"(mitochondrion)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0010992"(ubiquitin recycling)|go:"GO:0010995"(free ubiquitin chain depolymerization)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0031902"(late endosome membrane)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0070676"(intralumenal vesicle formation)|go:"GO:1904669"(ATP export)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR001763(Rhodanese-like)|interpro:IPR018200|interpro:IPR028889|interpro:IPR036873|interpro:IPR038765|refseq:NP_010354.3|dip:DIP-5298N|mint:P32571|sgd:YDR069C(identity)	-	no-uniprot-update:	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:WyH5VrQlZ4x7Sr5Hd4ApJ74qrL49606	rogid:UTBSWmpygyxo1ygxp/sQ8wgqnMo559292	intact-crc:D1775B04356A4FCB|rigid:mFA8pUXslEx569AJcgdfELXftIE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32571	uniprotkb:Q96ED9-2	intact:EBI-19840|uniprotkb:D6VS55|ensemblfungi:YDR069C	intact:EBI-10961706|ensembl:ENSP00000264827	psi-mi:ubp4_yeast(display_long)|uniprotkb:DOA4(gene name)|psi-mi:DOA4(display_short)|uniprotkb:MUT4(gene name synonym)|uniprotkb:SSV7(gene name synonym)|uniprotkb:YDR069C(locus name)|uniprotkb:YD9609.23C(orf name)|uniprotkb:YD8554.02C(orf name)|uniprotkb:D4270(orf name)|uniprotkb:NPI2(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 4(gene name synonym)|uniprotkb:Deubiquitinating enzyme 4(gene name synonym)|uniprotkb:Vacuole biogenesis protein SSV7(gene name synonym)|uniprotkb:Ubiquitin thioesterase 4(gene name synonym)|uniprotkb:DOS1(gene name synonym)|uniprotkb:UBP4(gene name synonym)	psi-mi:q96ed9-2(display_long)|uniprotkb:HOOK2(gene name)|psi-mi:HOOK2(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11526687|imex:IM-24995-452	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002476|ensemblfungi:YDR069C(gene)|ensemblfungi:YDR069C_mRNA(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005739"(mitochondrion)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0010992"(ubiquitin recycling)|go:"GO:0010995"(free ubiquitin chain depolymerization)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0031902"(late endosome membrane)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0070676"(intralumenal vesicle formation)|go:"GO:1904669"(ATP export)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR001763(Rhodanese-like)|interpro:IPR018200|interpro:IPR028889|interpro:IPR036873|interpro:IPR038765|refseq:NP_010354.3|dip:DIP-5298N|mint:P32571|sgd:YDR069C(identity)	ensembl:ENSG00000095066(gene)|ensembl:ENST00000264827(transcript)|intact:EBI-743290(isoform-parent)|uniprotkb:Q96ED9-2(isoform-parent)|entrezgene/locuslink:29911(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:UTBSWmpygyxo1ygxp/sQ8wgqnMo559292	rogid:aJZ/iDJpRk5dFL1NiouLuTjnOnc9606	intact-crc:EC9A9CFD2EF09EFF|rigid:u6BwzFlMwt2j4xi/nZM8QYjxRkI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q15025	uniprotkb:P32571	intact:EBI-357849|uniprotkb:A4F1W8|uniprotkb:O76008|uniprotkb:Q96EL9|uniprotkb:Q99833|uniprotkb:Q9H1J3|uniprotkb:B7Z699|uniprotkb:Q6N077|ensembl:ENSP00000317891|ensembl:ENSP00000428187|ensembl:ENSP00000430760|uniprotkb:A4F1W9|uniprotkb:A4F1X2|uniprotkb:A4F1X4|uniprotkb:A4F1X5|uniprotkb:A4F1X6|uniprotkb:A4F1X7|uniprotkb:A4F1X9|uniprotkb:E7EPY1|uniprotkb:E7ET96|uniprotkb:Q05KP3|uniprotkb:Q05KP4	intact:EBI-19840|uniprotkb:D6VS55|ensemblfungi:YDR069C	psi-mi:tnip1_human(display_long)|uniprotkb:TNIP1(gene name)|psi-mi:TNIP1(display_short)|uniprotkb:KIAA0113(gene name synonym)|uniprotkb:NAF1(gene name synonym)|uniprotkb:Nef-associated factor 1(gene name synonym)|uniprotkb:HIV-1 Nef-interacting protein(gene name synonym)|uniprotkb:Virion-associated nuclear shuttling protein(gene name synonym)|uniprotkb:Nip40-1(gene name synonym)|uniprotkb:A20-binding inhibitor of NF-kappa-B activation 1(gene name synonym)	psi-mi:ubp4_yeast(display_long)|uniprotkb:DOA4(gene name)|psi-mi:DOA4(display_short)|uniprotkb:MUT4(gene name synonym)|uniprotkb:SSV7(gene name synonym)|uniprotkb:YDR069C(locus name)|uniprotkb:YD9609.23C(orf name)|uniprotkb:YD8554.02C(orf name)|uniprotkb:D4270(orf name)|uniprotkb:NPI2(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 4(gene name synonym)|uniprotkb:Deubiquitinating enzyme 4(gene name synonym)|uniprotkb:Vacuole biogenesis protein SSV7(gene name synonym)|uniprotkb:Ubiquitin thioesterase 4(gene name synonym)|uniprotkb:DOS1(gene name synonym)|uniprotkb:UBP4(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11526659|imex:IM-24995-449	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006049.3|refseq:NP_001239319.1|refseq:NP_001239320.1|refseq:NP_001239321.1|refseq:NP_001239322.1|refseq:NP_001245383.1|dip:DIP-27577N|refseq:NP_001239315.1|ensembl:ENSG00000145901(gene)|ensembl:ENST00000315050(transcript)|ensembl:ENST00000521591(transcript)|ensembl:ENST00000522226(transcript)|go:"GO:0002755"(MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0006952"(defense response)|go:"GO:0006954"(inflammatory response)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0009101"(glycoprotein biosynthetic process)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0085032"(modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade)|go:"GO:1903003"(positive regulation of protein deubiquitination)|interpro:IPR033372|mint:Q15025|reactome:R-HSA-5689896|go:"GO:0051019"(mitogen-activated protein kinase binding)|refseq:NP_001239314.1|refseq:NP_001245384.1|refseq:NP_001245385.1|refseq:XP_006714814.1|refseq:XP_006714815.1|entrezgene/locuslink:10318(identity)	sgd:S000002476|ensemblfungi:YDR069C(gene)|ensemblfungi:YDR069C_mRNA(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005739"(mitochondrion)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0010992"(ubiquitin recycling)|go:"GO:0010995"(free ubiquitin chain depolymerization)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0031902"(late endosome membrane)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0070676"(intralumenal vesicle formation)|go:"GO:1904669"(ATP export)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR001763(Rhodanese-like)|interpro:IPR018200|interpro:IPR028889|interpro:IPR036873|interpro:IPR038765|refseq:NP_010354.3|dip:DIP-5298N|mint:P32571|sgd:YDR069C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:16Vjb5CuGTAbW2M22qbCxgXtV1o9606	rogid:UTBSWmpygyxo1ygxp/sQ8wgqnMo559292	intact-crc:7DA3B31C616448BA|rigid:ijitWknNv+h+mXOvzIRz19XPe8A	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32571	uniprotkb:Q5JR59-3	intact:EBI-19840|uniprotkb:D6VS55|ensemblfungi:YDR069C	intact:EBI-11522433|ensembl:ENSP00000370186	psi-mi:ubp4_yeast(display_long)|uniprotkb:DOA4(gene name)|psi-mi:DOA4(display_short)|uniprotkb:MUT4(gene name synonym)|uniprotkb:SSV7(gene name synonym)|uniprotkb:YDR069C(locus name)|uniprotkb:YD9609.23C(orf name)|uniprotkb:YD8554.02C(orf name)|uniprotkb:D4270(orf name)|uniprotkb:NPI2(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 4(gene name synonym)|uniprotkb:Deubiquitinating enzyme 4(gene name synonym)|uniprotkb:Vacuole biogenesis protein SSV7(gene name synonym)|uniprotkb:Ubiquitin thioesterase 4(gene name synonym)|uniprotkb:DOS1(gene name synonym)|uniprotkb:UBP4(gene name synonym)	psi-mi:q5jr59-3(display_long)|uniprotkb:MTUS2(gene name)|psi-mi:MTUS2(display_short)|uniprotkb:CAZIP(gene name synonym)|uniprotkb:Cardiac zipper protein(gene name synonym)|uniprotkb:KIAA0774(gene name synonym)|uniprotkb:Microtubule plus-end tracking protein TIP150(gene name synonym)|uniprotkb:TIP150(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11526669|imex:IM-24995-450	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002476|ensemblfungi:YDR069C(gene)|ensemblfungi:YDR069C_mRNA(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005739"(mitochondrion)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0010992"(ubiquitin recycling)|go:"GO:0010995"(free ubiquitin chain depolymerization)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0031902"(late endosome membrane)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0070676"(intralumenal vesicle formation)|go:"GO:1904669"(ATP export)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR001763(Rhodanese-like)|interpro:IPR018200|interpro:IPR028889|interpro:IPR036873|interpro:IPR038765|refseq:NP_010354.3|dip:DIP-5298N|mint:P32571|sgd:YDR069C(identity)	ensembl:ENSG00000132938(gene)|ensembl:ENST00000380808(transcript)|intact:EBI-742948(isoform-parent)|uniprotkb:Q5JR59-3(isoform-parent)|entrezgene/locuslink:23281(identity)	-	-	isoform-comment:No experimental confirmation available.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:UTBSWmpygyxo1ygxp/sQ8wgqnMo559292	rogid:npId9tC7VoLN/jteoBiRbSYChPs9606	intact-crc:DCF81C2DD3D279FF|rigid:mEWh4UkwNk8Pil//vX8dQyZ9SAA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32571	uniprotkb:Q8N6Y0	intact:EBI-19840|uniprotkb:D6VS55|ensemblfungi:YDR069C	intact:EBI-739895|uniprotkb:Q8NBX7|uniprotkb:Q96KH3|uniprotkb:Q9BYI8|uniprotkb:A8K7L6|uniprotkb:B2RCR9|ensembl:ENSP00000252597	psi-mi:ubp4_yeast(display_long)|uniprotkb:DOA4(gene name)|psi-mi:DOA4(display_short)|uniprotkb:MUT4(gene name synonym)|uniprotkb:SSV7(gene name synonym)|uniprotkb:YDR069C(locus name)|uniprotkb:YD9609.23C(orf name)|uniprotkb:YD8554.02C(orf name)|uniprotkb:D4270(orf name)|uniprotkb:NPI2(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 4(gene name synonym)|uniprotkb:Deubiquitinating enzyme 4(gene name synonym)|uniprotkb:Vacuole biogenesis protein SSV7(gene name synonym)|uniprotkb:Ubiquitin thioesterase 4(gene name synonym)|uniprotkb:DOS1(gene name synonym)|uniprotkb:UBP4(gene name synonym)	psi-mi:usbp1_human(display_long)|uniprotkb:USHBP1(gene name)|psi-mi:USHBP1(display_short)|uniprotkb:MCC-2(gene name synonym)|uniprotkb:AIE-75-binding protein(gene name synonym)|uniprotkb:AIEBP(gene name synonym)|uniprotkb:MCC2(gene name synonym)|uniprotkb:Mutated in colon cancer protein 2(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11526678|imex:IM-24995-451	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002476|ensemblfungi:YDR069C(gene)|ensemblfungi:YDR069C_mRNA(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005739"(mitochondrion)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0010992"(ubiquitin recycling)|go:"GO:0010995"(free ubiquitin chain depolymerization)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0031902"(late endosome membrane)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0070676"(intralumenal vesicle formation)|go:"GO:1904669"(ATP export)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR001763(Rhodanese-like)|interpro:IPR018200|interpro:IPR028889|interpro:IPR036873|interpro:IPR038765|refseq:NP_010354.3|dip:DIP-5298N|mint:P32571|sgd:YDR069C(identity)	refseq:NP_001284632.1|refseq:NP_114147.2|refseq:NP_001308346.1|ensembl:ENSG00000130307(gene)|ensembl:ENST00000252597(transcript)|go:"GO:0030165"(PDZ domain binding)|interpro:IPR019536|interpro:IPR040171|entrezgene/locuslink:83878(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:UTBSWmpygyxo1ygxp/sQ8wgqnMo559292	rogid:vY1qx73Ju/z7WDu6k1kd10ZDVRo9606	intact-crc:4C82BE8FA204F90C|rigid:DN8zgK0GuI+aCXH3yiBoVoqrj3U	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32589	uniprotkb:Q99750	intact:EBI-8648|uniprotkb:D6W3R1|ensemblfungi:YPL106C	intact:EBI-724076|ensembl:ENSP00000230321|ensembl:ENSP00000362142	psi-mi:hsp7f_yeast(display_long)|uniprotkb:SSE1(gene name)|psi-mi:SSE1(display_short)|uniprotkb:MSI3(gene name synonym)|uniprotkb:YPL106C(locus name)|uniprotkb:LPG3C(orf name)|uniprotkb:Chaperone protein MSI3(gene name synonym)	psi-mi:mdfi_human(display_long)|uniprotkb:Myogenic repressor I-mf(gene name synonym)|uniprotkb:MDFI(gene name)|psi-mi:MDFI(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11526723|imex:IM-24995-456	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015219.1|sgd:S000006027|mint:P32589|dip:DIP-6645N|ensemblfungi:YPL106C(gene)|ensemblfungi:YPL106C_mRNA(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0006457"(protein folding)|go:"GO:0006914"(autophagy)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0042026"(protein refolding)|go:"GO:0042277"(peptide binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|rcsb pdb:2QXL|rcsb pdb:3C7N|rcsb pdb:3D2E|rcsb pdb:3D2F|sgd:YPL106C(identity)	refseq:NP_005577.1|ensembl:ENSG00000112559(gene)|ensembl:ENST00000230321(transcript)|ensembl:ENST00000373051(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR026134|mint:Q99750|refseq:NP_001287733.1|refseq:NP_001287734.1|refseq:NP_001287735.1|entrezgene/locuslink:4188(identity)	-	crc64:6558259111B0BC38	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:16yTg05haoflKGNZTW4EqC7FSs0559292	rogid:V3vU0fihMOW18DMHAiDbuZ3asNU9606	intact-crc:D6EBE1F0ABCDB364|rigid:p5E3oQwlivMCNoDUDVqTwze95nY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96MT8-3	uniprotkb:P32571	intact:EBI-11522539|ensembl:ENSP00000507703|ensembl:ENSP00000328382|ensembl:ENSP00000506728|ensembl:ENSP00000506791|ensembl:ENSP00000506828|ensembl:ENSP00000507228	intact:EBI-19840|uniprotkb:D6VS55|ensemblfungi:YDR069C	psi-mi:q96mt8-3(display_long)|uniprotkb:CEP63(gene name)|psi-mi:CEP63(display_short)	psi-mi:ubp4_yeast(display_long)|uniprotkb:DOA4(gene name)|psi-mi:DOA4(display_short)|uniprotkb:MUT4(gene name synonym)|uniprotkb:SSV7(gene name synonym)|uniprotkb:YDR069C(locus name)|uniprotkb:YD9609.23C(orf name)|uniprotkb:YD8554.02C(orf name)|uniprotkb:D4270(orf name)|uniprotkb:NPI2(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 4(gene name synonym)|uniprotkb:Deubiquitinating enzyme 4(gene name synonym)|uniprotkb:Vacuole biogenesis protein SSV7(gene name synonym)|uniprotkb:Ubiquitin thioesterase 4(gene name synonym)|uniprotkb:DOS1(gene name synonym)|uniprotkb:UBP4(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11526696|imex:IM-24995-453	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-741977(isoform-parent)|ensembl:ENST00000332047(transcript)|ensembl:ENST00000682042(transcript)|ensembl:ENST00000682800(transcript)|ensembl:ENST00000682858(transcript)|ensembl:ENST00000683177(transcript)|ensembl:ENST00000683861(transcript)|ensembl:ENSG00000182923(gene)|uniprotkb:Q96MT8-3(isoform-parent)|entrezgene/locuslink:80254(identity)	sgd:S000002476|ensemblfungi:YDR069C(gene)|ensemblfungi:YDR069C_mRNA(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005739"(mitochondrion)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0010992"(ubiquitin recycling)|go:"GO:0010995"(free ubiquitin chain depolymerization)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0031902"(late endosome membrane)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0070676"(intralumenal vesicle formation)|go:"GO:1904669"(ATP export)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR001763(Rhodanese-like)|interpro:IPR018200|interpro:IPR028889|interpro:IPR036873|interpro:IPR038765|refseq:NP_010354.3|dip:DIP-5298N|mint:P32571|sgd:YDR069C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:U0uvVcOCzA8Qp2cCB0ilixgd4Yc9606	rogid:UTBSWmpygyxo1ygxp/sQ8wgqnMo559292	intact-crc:A265EC56DE3FF69F|rigid:kI8D2HOV+rSIzOY7Cz4dnMIPdhc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9NSC5	uniprotkb:P32571	intact:EBI-748420|uniprotkb:O14580|uniprotkb:O95350|uniprotkb:Q9NSB9|uniprotkb:Q9NSC0|intact:EBI-2557809|uniprotkb:E9PCW9|uniprotkb:Q9NSC1|intact:EBI-28972925|ensembl:ENSP00000376162|ensembl:ENSP00000439937|ensembl:ENSP00000446026|intact:EBI-10175777|uniprotkb:B2RA10	intact:EBI-19840|uniprotkb:D6VS55|ensemblfungi:YDR069C	psi-mi:home3_human(display_long)|uniprotkb:HOMER3(gene name)|psi-mi:HOMER3(display_short)	psi-mi:ubp4_yeast(display_long)|uniprotkb:DOA4(gene name)|psi-mi:DOA4(display_short)|uniprotkb:MUT4(gene name synonym)|uniprotkb:SSV7(gene name synonym)|uniprotkb:YDR069C(locus name)|uniprotkb:YD9609.23C(orf name)|uniprotkb:YD8554.02C(orf name)|uniprotkb:D4270(orf name)|uniprotkb:NPI2(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 4(gene name synonym)|uniprotkb:Deubiquitinating enzyme 4(gene name synonym)|uniprotkb:Vacuole biogenesis protein SSV7(gene name synonym)|uniprotkb:Ubiquitin thioesterase 4(gene name synonym)|uniprotkb:DOS1(gene name synonym)|uniprotkb:UBP4(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11526705|imex:IM-24995-454	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000221222|ensembl:ENSP00000221222|ensembl:ENSP00000376162|ensembl:ENST00000433218|ensembl:ENSP00000396154|ensembl:ENSP00000439937|ensembl:ENSP00000446026|ensembl:ENST00000594439|ensembl:ENSP00000471835|refseq:XP_006723006.1|refseq:XP_006723007.1|refseq:NP_001139193.1|refseq:NP_001139194.1|refseq:NP_004829.3|refseq:NP_001139196.1|ensembl:ENSG00000051128(gene)|ensembl:ENST00000392351(transcript)|ensembl:ENST00000539827(transcript)|ensembl:ENST00000542541(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006605"(protein targeting)|go:"GO:0007216"(G protein-coupled glutamate receptor signaling pathway)|go:"GO:0014069"(postsynaptic density)|go:"GO:0030425"(dendrite)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0035256"(G protein-coupled glutamate receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|go:"GO:2001256"(regulation of store-operated calcium entry)|interpro:IPR000697(EVH1)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR044100|mint:Q9NSC5|rcsb pdb:2P8V|rcsb pdb:3CVF|reactome:R-HSA-6794361|entrezgene/locuslink:9454(identity)	sgd:S000002476|ensemblfungi:YDR069C(gene)|ensemblfungi:YDR069C_mRNA(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005739"(mitochondrion)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0010992"(ubiquitin recycling)|go:"GO:0010995"(free ubiquitin chain depolymerization)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0031902"(late endosome membrane)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0070676"(intralumenal vesicle formation)|go:"GO:1904669"(ATP export)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR001763(Rhodanese-like)|interpro:IPR018200|interpro:IPR028889|interpro:IPR036873|interpro:IPR038765|refseq:NP_010354.3|dip:DIP-5298N|mint:P32571|sgd:YDR069C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:U1y/y52nnf7zQUCNQlqk7JDgXi49606	rogid:UTBSWmpygyxo1ygxp/sQ8wgqnMo559292	intact-crc:551BA1A4F319D8EE|rigid:9DyDDr3Gmjn5La0X0Ir9/eLyM+c	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32571	uniprotkb:Q9Y6D9	intact:EBI-19840|uniprotkb:D6VS55|ensemblfungi:YDR069C	intact:EBI-742610|uniprotkb:B3KR41|uniprotkb:Q9UNH0|uniprotkb:Q13312|uniprotkb:Q75MI0|uniprotkb:Q86UM4|ensembl:ENSP00000265854|ensembl:ENSP00000382562|ensembl:ENSP00000385334	psi-mi:ubp4_yeast(display_long)|uniprotkb:DOA4(gene name)|psi-mi:DOA4(display_short)|uniprotkb:MUT4(gene name synonym)|uniprotkb:SSV7(gene name synonym)|uniprotkb:YDR069C(locus name)|uniprotkb:YD9609.23C(orf name)|uniprotkb:YD8554.02C(orf name)|uniprotkb:D4270(orf name)|uniprotkb:NPI2(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 4(gene name synonym)|uniprotkb:Deubiquitinating enzyme 4(gene name synonym)|uniprotkb:Vacuole biogenesis protein SSV7(gene name synonym)|uniprotkb:Ubiquitin thioesterase 4(gene name synonym)|uniprotkb:DOS1(gene name synonym)|uniprotkb:UBP4(gene name synonym)	psi-mi:md1l1_human(display_long)|uniprotkb:Mitotic arrest deficient 1-like protein 1(gene name synonym)|uniprotkb:Mitotic checkpoint MAD1 protein homolog(gene name synonym)|uniprotkb:Tax-binding protein 181(gene name synonym)|uniprotkb:MAD1L1(gene name)|psi-mi:MAD1L1(display_short)|uniprotkb:MAD1(gene name synonym)|uniprotkb:TXBP181(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11526714|imex:IM-24995-455	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002476|ensemblfungi:YDR069C(gene)|ensemblfungi:YDR069C_mRNA(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005739"(mitochondrion)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0010992"(ubiquitin recycling)|go:"GO:0010995"(free ubiquitin chain depolymerization)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0031902"(late endosome membrane)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0070676"(intralumenal vesicle formation)|go:"GO:1904669"(ATP export)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR001763(Rhodanese-like)|interpro:IPR018200|interpro:IPR028889|interpro:IPR036873|interpro:IPR038765|refseq:NP_010354.3|dip:DIP-5298N|mint:P32571|sgd:YDR069C(identity)	refseq:NP_001013858.1|refseq:NP_001013859.1|refseq:NP_003541.2|refseq:NP_001291452.1|refseq:NP_001291453.1|ensembl:ENSG00000002822(gene)|ensembl:ENST00000265854(transcript)|go:"GO:0090235"(regulation of metaphase plate congression)|go:"GO:1902426"(deactivation of mitotic spindle assembly checkpoint)|interpro:IPR008672(Mitotic checkpoint)|mint:Q9Y6D9|rcsb pdb:1GO4|rcsb pdb:4DZO|rcsb pdb:7B1F|rcsb pdb:7B1H|rcsb pdb:7B1J|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|ensembl:ENST00000399654(transcript)|ensembl:ENST00000406869(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043515"(kinetochore binding)|go:"GO:0044615"(nuclear pore nuclear basket)|go:"GO:0048538"(thymus development)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0072686"(mitotic spindle)|refseq:XP_005249934.1|dip:DIP-29654N|entrezgene/locuslink:8379(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:UTBSWmpygyxo1ygxp/sQ8wgqnMo559292	rogid:9CcqpZlN0IgqC939rIo7vNgOvLQ9606	intact-crc:7954666A0A63E769|rigid:SJ0gDSH+tfkGAInWADUpSnggA8Y	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48775	uniprotkb:P32610	intact:EBI-743494|ensembl:ENSP00000444788|ensembl:ENSP00000460086|uniprotkb:A8K053	intact:EBI-20264|uniprotkb:D3DLJ9|ensemblfungi:YEL051W	psi-mi:t23o_human(display_long)|uniprotkb:Tryptophan pyrrolase(gene name synonym)|uniprotkb:Tryptophan oxygenase(gene name synonym)|uniprotkb:Tryptamin 2,3-dioxygenase(gene name synonym)|uniprotkb:TDO2(gene name)|psi-mi:TDO2(display_short)|uniprotkb:TDO(gene name synonym)|uniprotkb:Tryptophanase(gene name synonym)	psi-mi:vatd_yeast(display_long)|uniprotkb:VMA8(gene name)|psi-mi:VMA8(display_short)|uniprotkb:YEL051W(locus name)|uniprotkb:SYGP-ORF11(orf name)|uniprotkb:Vacuolar proton pump subunit D(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11526750|imex:IM-24995-459	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000151790(gene)|ensembl:ENSG00000262635(gene)|ensembl:ENST00000536354(transcript)|ensembl:ENST00000573403(transcript)|go:"GO:0004833"(tryptophan 2,3-dioxygenase activity)|go:"GO:0005829"(cytosol)|go:"GO:0016597"(amino acid binding)|go:"GO:0019441"(tryptophan catabolic process to kynurenine)|go:"GO:0019442"(tryptophan catabolic process to acetyl-CoA)|go:"GO:0019825"(oxygen binding)|go:"GO:0020037"(heme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051289"(protein homotetramerization)|go:"GO:1904842"(response to nitroglycerin)|interpro:IPR004981(Tryptophan 2,3-dioxygenase)|interpro:IPR037217|mint:P48775|rcsb pdb:4PW8|rcsb pdb:5TI9|rcsb pdb:5TIA|rcsb pdb:6A4I|rcsb pdb:6PYY|rcsb pdb:6PYZ|rcsb pdb:6UD5|rcsb pdb:6VBN|reactome:R-HSA-71240|refseq:NP_005642.1|entrezgene/locuslink:6999(identity)	refseq:NP_010863.1|sgd:S000000777|ensemblfungi:YEL051W(gene)|ensemblfungi:YEL051W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0016471"(vacuolar proton-transporting V-type ATPase complex)|go:"GO:0033176"(proton-transporting V-type ATPase complex)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR002699(ATPase, V1/A1 complex, subunit D)|rcsb pdb:3J9T|rcsb pdb:3J9U|rcsb pdb:3J9V|rcsb pdb:4RND|rcsb pdb:5BW9|rcsb pdb:5D80|rcsb pdb:5VOX|rcsb pdb:5VOY|rcsb pdb:5VOZ|rcsb pdb:6O7V|rcsb pdb:6O7W|rcsb pdb:6O7X|reactome:R-SCE-1222556|reactome:R-SCE-6798695|reactome:R-SCE-77387|reactome:R-SCE-917977|reactome:R-SCE-9639288|dip:DIP-2959N|mint:P32610|sgd:YEL051W(identity)	-	-	crc64:FDE93E1FAF0AEC5B	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:S+cyc710I52nIFQWgKhXFul9QZw9606	rogid:rrwRno7lCnDeTNwawONkGwV8Hkg559292	intact-crc:547E564A0E4D3E04|rigid:k/4RXew9tqL8bMsUlj6jyHMJQ30	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32601	uniprotkb:P26641	intact:EBI-6178|uniprotkb:Q12299|uniprotkb:Q3S1N1|uniprotkb:D6W427|ensemblfungi:YPR017C	intact:EBI-351467|uniprotkb:Q6PJ62|uniprotkb:Q6PK31|uniprotkb:Q96CU2|uniprotkb:Q9P196|intact:EBI-2321928|uniprotkb:B4DTG2|ensembl:ENSP00000331901	psi-mi:dss4_yeast(display_long)|uniprotkb:DSS4(gene name)|psi-mi:DSS4(display_short)|uniprotkb:LPZ16C(orf name)|uniprotkb:YP9531.11C(orf name)|uniprotkb:YPR017C(locus name)	psi-mi:ef1g_human(display_long)|uniprotkb:PRO1608(orf name)|uniprotkb:EEF1G(gene name)|psi-mi:EEF1G(display_short)|uniprotkb:EF1G(gene name synonym)|uniprotkb:eEF-1B gamma(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11526732|imex:IM-24995-457	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015342.1|sgd:S000006221|dip:DIP-1423N|ensemblfungi:YPR017C(gene)|ensemblfungi:YPR017C_mRNA(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008270"(zinc ion binding)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|interpro:IPR007515(Mss4)|interpro:IPR011057(Mss4-like)|interpro:IPR011323(Mss4/translationally controlled tumour-associated TCTP)|sgd:YPR017C(identity)	refseq:NP_001395.1|ensembl:ENSG00000254772(gene)|ensembl:ENST00000329251(transcript)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006414"(translational elongation)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001662(Translation elongation factor EF1B, gamma chain, conserved)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR036249|interpro:IPR036282|interpro:IPR036433|interpro:IPR040079|mint:P26641|rcsb pdb:1PBU|rcsb pdb:5DQS|rcsb pdb:5JPO|reactome:R-HSA-156842|dip:DIP-32516N|entrezgene/locuslink:1937(identity)	-	crc64:1D7B6D3443D93AE2	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:UKF+4mfZLTZ2s5CLkImTGcwgvUw559292	rogid:biVN96umeEdPm/wvPN4VwbSRHTs9606	intact-crc:D9E184478BE6FA23|rigid:EvKgM1/2L6A7SHxeu5xsDJiMmf4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P19012	uniprotkb:P32610	intact:EBI-739566|uniprotkb:Q53XV8|uniprotkb:Q9BUG4|uniprotkb:B3KQY1|uniprotkb:B3KRA2|uniprotkb:E0CX14|ensembl:ENSP00000254043|ensembl:ENSP00000377546	intact:EBI-20264|uniprotkb:D3DLJ9|ensemblfungi:YEL051W	psi-mi:k1c15_human(display_long)|uniprotkb:KRT15(gene name)|psi-mi:KRT15(display_short)|uniprotkb:KRTB(gene name synonym)|uniprotkb:Cytokeratin-15(gene name synonym)|uniprotkb:Keratin-15(gene name synonym)	psi-mi:vatd_yeast(display_long)|uniprotkb:VMA8(gene name)|psi-mi:VMA8(display_short)|uniprotkb:YEL051W(locus name)|uniprotkb:SYGP-ORF11(orf name)|uniprotkb:Vacuolar proton pump subunit D(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11526741|imex:IM-24995-458	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002266.2|ensembl:ENSG00000171346(gene)|ensembl:ENST00000254043(transcript)|ensembl:ENST00000393976(transcript)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0008544"(epidermis development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097110"(scaffold protein binding)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR039008|mint:P19012|reactome:R-HSA-6805567|reactome:R-HSA-6809371|entrezgene/locuslink:3866(identity)	refseq:NP_010863.1|sgd:S000000777|ensemblfungi:YEL051W(gene)|ensemblfungi:YEL051W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0016471"(vacuolar proton-transporting V-type ATPase complex)|go:"GO:0033176"(proton-transporting V-type ATPase complex)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR002699(ATPase, V1/A1 complex, subunit D)|rcsb pdb:3J9T|rcsb pdb:3J9U|rcsb pdb:3J9V|rcsb pdb:4RND|rcsb pdb:5BW9|rcsb pdb:5D80|rcsb pdb:5VOX|rcsb pdb:5VOY|rcsb pdb:5VOZ|rcsb pdb:6O7V|rcsb pdb:6O7W|rcsb pdb:6O7X|reactome:R-SCE-1222556|reactome:R-SCE-6798695|reactome:R-SCE-77387|reactome:R-SCE-917977|reactome:R-SCE-9639288|dip:DIP-2959N|mint:P32610|sgd:YEL051W(identity)	-	-	crc64:FDE93E1FAF0AEC5B	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:WrZQBYQvrWcfrR5ojWXrXp6spPE9606	rogid:rrwRno7lCnDeTNwawONkGwV8Hkg559292	intact-crc:EA9A9526BB514778|rigid:xGHgIT8Lu5s5UtthxS5AsbS9L9E	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O95544	uniprotkb:P32622	intact:EBI-743949|uniprotkb:Q9H931|uniprotkb:A8K296|uniprotkb:A6NNN3|uniprotkb:B7Z434|uniprotkb:F5GXR5|uniprotkb:Q5QPS4|uniprotkb:Q9H2P2|ensembl:ENSP00000341679|ensembl:ENSP00000344340	intact:EBI-22350|uniprotkb:D3DLK8|ensemblfungi:YEL041W	psi-mi:nadk_human(display_long)|uniprotkb:"Poly(P)/ATP NAD kinase"(gene name synonym)|uniprotkb:NADK(gene name)|psi-mi:NADK(display_short)	psi-mi:yef1_yeast(display_long)|uniprotkb:YEF1(gene name)|psi-mi:YEF1(display_short)|uniprotkb:SYGP-ORF17(orf name)|uniprotkb:YEL041W(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11526786|imex:IM-24995-463	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001185922.1|refseq:NP_001185923.1|refseq:NP_001185924.1|refseq:NP_075394.3|refseq:XP_005244835.1|refseq:XP_006710900.1|ensembl:ENSG00000008130(gene)|ensembl:ENST00000341426(transcript)|ensembl:ENST00000341991(transcript)|go:"GO:0003951"(NAD+ kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006741"(NADP biosynthetic process)|go:"GO:0016310"(phosphorylation)|go:"GO:0019674"(NAD metabolic process)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046872"(metal ion binding)|interpro:IPR002504(ATP-NAD/AcoX kinase)|interpro:IPR016064(ATP-NAD kinase, PpnK-type)|interpro:IPR017437(ATP-NAD kinase, PpnK-type, all-beta)|interpro:IPR017438(ATP-NAD kinase, PpnK-type, alpha/beta)|mint:O95544|rcsb pdb:3PFN|reactome:R-HSA-196807|entrezgene/locuslink:65220(identity)	refseq:NP_010873.1|sgd:S000000767|dip:DIP-1885N|mint:P32622|ensemblfungi:YEL041W(gene)|ensemblfungi:YEL041W_mRNA(transcript)|go:"GO:0003951"(NAD+ kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006741"(NADP biosynthetic process)|go:"GO:0019674"(NAD metabolic process)|go:"GO:0042736"(NADH kinase activity)|interpro:IPR002504(ATP-NAD/AcoX kinase)|interpro:IPR016064(ATP-NAD kinase, PpnK-type)|interpro:IPR017437(ATP-NAD kinase, PpnK-type, all-beta)|interpro:IPR017438(ATP-NAD kinase, PpnK-type, alpha/beta)|sgd:YEL041W(identity)	-	-	crc64:E8301D466249DA27	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:XPfRviZiKsV+1JOUi7BsMrIa3M49606	rogid:HAL9emGKdVRCmdDG9CMzn68CGUI559292	intact-crc:5D220BB796FA579C|rigid:/mJyZP7jnOwR5pOfg2RO3cVZgVU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96EV8	uniprotkb:P32610	intact:EBI-465804|uniprotkb:Q5THY3|uniprotkb:Q5THY4|uniprotkb:Q96NV2|intact:EBI-28986386|ensembl:ENSP00000341680|uniprotkb:Q9H0U2|uniprotkb:Q9H3J5|uniprotkb:A8K3V3	intact:EBI-20264|uniprotkb:D3DLJ9|ensemblfungi:YEL051W	psi-mi:dtbp1_human(display_long)|uniprotkb:My031(orf name)|uniprotkb:DTNBP1(gene name)|psi-mi:DTNBP1(display_short)|uniprotkb:Dystrobrevin-binding protein 1(gene name synonym)|uniprotkb:Hermansky-Pudlak syndrome 7 protein(gene name synonym)|uniprotkb:Dysbindin-1(gene name synonym)|uniprotkb:BLOC1S8(gene name synonym)|uniprotkb:Biogenesis of lysosome-related organelles complex 1 subunit 8(gene name synonym)	psi-mi:vatd_yeast(display_long)|uniprotkb:VMA8(gene name)|psi-mi:VMA8(display_short)|uniprotkb:YEL051W(locus name)|uniprotkb:SYGP-ORF11(orf name)|uniprotkb:Vacuolar proton pump subunit D(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11526759|imex:IM-24995-460	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000047579(gene)|ensembl:ENST00000344537(transcript)|go:"GO:0001956"(positive regulation of neurotransmitter secretion)|go:"GO:0005634"(nucleus)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007596"(blood coagulation)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014059"(regulation of dopamine secretion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016528"(sarcoplasm)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0030496"(midbody)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032438"(melanosome organization)|go:"GO:0033162"(melanosome membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0043005"(neuron projection)|go:"GO:0043197"(dendritic spine)|go:"GO:0005737"(cytoplasm)|go:"GO:0043506"(regulation of JUN kinase activity)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0060155"(platelet dense granule organization)|go:"GO:0060159"(regulation of dopamine receptor signaling pathway)|go:"GO:0071901"(negative regulation of protein serine/threonine kinase activity)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR007531(Dysbindin)|reactome:R-HSA-432722|go:"GO:0048490"(anterograde synaptic vesicle transport)|refseq:NP_115498.2|refseq:NP_898861.1|refseq:NP_001258597.1|refseq:NP_001258598.1|ensembl:ENST00000338950|ensembl:ENSP00000344718|ensembl:ENSP00000341680|refseq:NP_001258596.1|entrezgene/locuslink:84062(identity)	refseq:NP_010863.1|sgd:S000000777|ensemblfungi:YEL051W(gene)|ensemblfungi:YEL051W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0016471"(vacuolar proton-transporting V-type ATPase complex)|go:"GO:0033176"(proton-transporting V-type ATPase complex)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR002699(ATPase, V1/A1 complex, subunit D)|rcsb pdb:3J9T|rcsb pdb:3J9U|rcsb pdb:3J9V|rcsb pdb:4RND|rcsb pdb:5BW9|rcsb pdb:5D80|rcsb pdb:5VOX|rcsb pdb:5VOY|rcsb pdb:5VOZ|rcsb pdb:6O7V|rcsb pdb:6O7W|rcsb pdb:6O7X|reactome:R-SCE-1222556|reactome:R-SCE-6798695|reactome:R-SCE-77387|reactome:R-SCE-917977|reactome:R-SCE-9639288|dip:DIP-2959N|mint:P32610|sgd:YEL051W(identity)	-	-	crc64:FDE93E1FAF0AEC5B	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:PBwxp1vobm9l5yGoqev97lzkMHg9606	rogid:rrwRno7lCnDeTNwawONkGwV8Hkg559292	intact-crc:3551493F47F19455|rigid:SIIATUHtRJRLyRIKE2irBgkXGmA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32610	uniprotkb:Q9BUW7	intact:EBI-20264|uniprotkb:D3DLJ9|ensemblfungi:YEL051W	intact:EBI-752084|uniprotkb:Q9Y3F7|uniprotkb:Q5SYV8|ensembl:ENSP00000362085	psi-mi:vatd_yeast(display_long)|uniprotkb:VMA8(gene name)|psi-mi:VMA8(display_short)|uniprotkb:YEL051W(locus name)|uniprotkb:SYGP-ORF11(orf name)|uniprotkb:Vacuolar proton pump subunit D(gene name synonym)	psi-mi:bbln_human(display_long)|uniprotkb:BBLN(gene name)|psi-mi:BBLN(display_short)|uniprotkb:C9orf16(gene name synonym)|uniprotkb:UPF0184 protein C9orf16(gene name synonym)|uniprotkb:EST00098(orf name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11526768|imex:IM-24995-461	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010863.1|sgd:S000000777|ensemblfungi:YEL051W(gene)|ensemblfungi:YEL051W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0016471"(vacuolar proton-transporting V-type ATPase complex)|go:"GO:0033176"(proton-transporting V-type ATPase complex)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR002699(ATPase, V1/A1 complex, subunit D)|rcsb pdb:3J9T|rcsb pdb:3J9U|rcsb pdb:3J9V|rcsb pdb:4RND|rcsb pdb:5BW9|rcsb pdb:5D80|rcsb pdb:5VOX|rcsb pdb:5VOY|rcsb pdb:5VOZ|rcsb pdb:6O7V|rcsb pdb:6O7W|rcsb pdb:6O7X|reactome:R-SCE-1222556|reactome:R-SCE-6798695|reactome:R-SCE-77387|reactome:R-SCE-917977|reactome:R-SCE-9639288|dip:DIP-2959N|mint:P32610|sgd:YEL051W(identity)	refseq:NP_077017.1|dip:DIP-29481N|ensembl:ENSG00000171159(gene)|ensembl:ENST00000372994(transcript)|interpro:IPR005374(Protein of unknown function UPF0184)|entrezgene/locuslink:79095(identity)	-	crc64:FDE93E1FAF0AEC5B	crc64:EBE1D0AFAAD6DABB	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:rrwRno7lCnDeTNwawONkGwV8Hkg559292	rogid:O4VcHghk63gMrjyh5XKmkZovFZ49606	intact-crc:9E92D6FF305F225E|rigid:HBf3s4T1v7ErHlrRAY5ESbOe+30	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32614	uniprotkb:Q15102	intact:EBI-22366|uniprotkb:D3DLK3|ensemblfungi:YEL047C	intact:EBI-711522|uniprotkb:Q53X88|ensembl:ENSP00000262890|ensembl:ENSP00000444935	psi-mi:frds_yeast(display_long)|uniprotkb:FRD1(gene name)|psi-mi:FRD1(display_short)|uniprotkb:FAD-dependent oxidoreductase(gene name synonym)|uniprotkb:FRDS(gene name synonym)|uniprotkb:FRDS1(gene name synonym)|uniprotkb:NADH-dependent fumarate reductase(gene name synonym)|uniprotkb:Soluble fumarate reductase, cytoplasmic isozyme(gene name synonym)|uniprotkb:SYGP-ORF35(orf name)|uniprotkb:YEL047C(locus name)	psi-mi:pa1b3_human(display_long)|uniprotkb:PAFAH1B3(gene name)|psi-mi:PAFAH1B3(display_short)|uniprotkb:PAFAHG(gene name synonym)|uniprotkb:PAF acetylhydrolase 29 kDa subunit(gene name synonym)|uniprotkb:PAF-AH subunit gamma(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11526777|imex:IM-24995-462	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000000773|refseq:NP_010867.3|dip:DIP-5287N|mint:P32614|ensemblfungi:YEL047C(gene)|ensemblfungi:YEL047C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010181"(FMN binding)|go:"GO:0016156"("fumarate reductase (NADH) activity")|go:"GO:0071454"(cellular response to anoxia)|interpro:IPR003953(Fumarate reductase/succinate dehydrogenase flavoprotein, N-terminal)|interpro:IPR010960(Flavocytochrome c)|interpro:IPR027477|interpro:IPR036188|sgd:YEL047C(identity)	go:"GO:0016042"(lipid catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0047179"(platelet-activating factor acetyltransferase activity)|interpro:IPR013830(Esterase, SGNH hydrolase-type)|interpro:IPR036514|mint:Q15102|reactome:R-HSA-6811436|go:"GO:0005829"(cytosol)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0008247"(1-alkyl-2-acetylglycerophosphocholine esterase complex)|go:"GO:0016020"(membrane)|ensembl:ENSG00000079462(gene)|ensembl:ENST00000262890(transcript)|ensembl:ENST00000538771(transcript)|go:"GO:0003847"(1-alkyl-2-acetylglycerophosphocholine esterase activity)|go:"GO:0005737"(cytoplasm)|refseq:NP_001139411.1|refseq:NP_001139412.1|refseq:NP_002564.1|entrezgene/locuslink:5050(identity)	-	crc64:63C30B39252DC935	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:hkn/l2LN9LMWWw+e7kXvRXVqvr4559292	rogid:yxVKkXAs2AmH+fZFUW+hZN889k89606	intact-crc:A7205031B64727AE|rigid:sZ95JGMiTAmt5QKEhbl5f/wX+OE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32831	uniprotkb:Q08379	intact:EBI-12002|ensemblfungi:YBR212W|uniprotkb:D6VQK8	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	psi-mi:ngr1_yeast(display_long)|uniprotkb:NGR1(gene name)|psi-mi:NGR1(display_short)|uniprotkb:RBP1(gene name synonym)|uniprotkb:YBR212W(locus name)|uniprotkb:YBR1459(orf name)|uniprotkb:RNA-binding protein RBP1(gene name synonym)	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11526813|imex:IM-24995-466	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YBR212W(gene)|ensemblfungi:YBR212W_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|refseq:NP_009771.3|sgd:S000000416|mint:P32831|dip:DIP-5160N|sgd:YBR212W(identity)	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N|entrezgene/locuslink:2801(identity)	-	crc64:12F64EC4C5716750	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2017/05/26	rogid:MCNbYrmWkUp7dAyKpebSKsIzOxA559292	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	intact-crc:063F6EBD9EB70D14|rigid:v3TpDbdeJVmyOr+hoErXJ5VXAF0	false	-	sufficient binding region:383-1002	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32622	uniprotkb:P19474	intact:EBI-22350|uniprotkb:D3DLK8|ensemblfungi:YEL041W	intact:EBI-81290|uniprotkb:Q96RF8|uniprotkb:Q5XPV5|ensembl:ENSP00000254436	psi-mi:yef1_yeast(display_long)|uniprotkb:YEF1(gene name)|psi-mi:YEF1(display_short)|uniprotkb:SYGP-ORF17(orf name)|uniprotkb:YEL041W(locus name)	psi-mi:ro52_human(display_long)|uniprotkb:TRIM21(gene name)|psi-mi:TRIM21(display_short)|uniprotkb:RNF81(gene name synonym)|uniprotkb:Sjoegren syndrome type A antigen(gene name synonym)|uniprotkb:"Ro(SS-A)"(gene name synonym)|uniprotkb:52 kDa ribonucleoprotein autoantigen Ro/SS-A(gene name synonym)|uniprotkb:Tripartite motif-containing protein 21(gene name synonym)|uniprotkb:RING finger protein 81(gene name synonym)|uniprotkb:52 kDa Ro protein(gene name synonym)|uniprotkb:RO52(gene name synonym)|uniprotkb:SSA1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM21(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11526795|imex:IM-24995-464	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010873.1|sgd:S000000767|dip:DIP-1885N|mint:P32622|ensemblfungi:YEL041W(gene)|ensemblfungi:YEL041W_mRNA(transcript)|go:"GO:0003951"(NAD+ kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006741"(NADP biosynthetic process)|go:"GO:0019674"(NAD metabolic process)|go:"GO:0042736"(NADH kinase activity)|interpro:IPR002504(ATP-NAD/AcoX kinase)|interpro:IPR016064(ATP-NAD kinase, PpnK-type)|interpro:IPR017437(ATP-NAD kinase, PpnK-type, all-beta)|interpro:IPR017438(ATP-NAD kinase, PpnK-type, alpha/beta)|sgd:YEL041W(identity)	refseq:NP_003132.2|go:"GO:0019901"(protein kinase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031648"(protein destabilization)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032479"(regulation of type I interferon production)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045824"(negative regulation of innate immune response)|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046598"(positive regulation of viral entry into host cell)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0090086"(negative regulation of protein deubiquitination)|ensembl:ENSG00000132109(gene)|ensembl:ENST00000254436(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000932"(P-body)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0007049"(cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR020457|interpro:IPR035831|interpro:IPR043136|mint:P19474|rcsb pdb:2IWG|rcsb pdb:5JPX|rcsb pdb:5OLM|rcsb pdb:6FGA|rcsb pdb:6S53|rcsb pdb:7BBD|reactome:R-HSA-1834941|reactome:R-HSA-3134975|reactome:R-HSA-877300|reactome:R-HSA-983168|go:"GO:1902187"|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003613(U box)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|entrezgene/locuslink:6737(identity)	-	crc64:E8301D466249DA27	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:HAL9emGKdVRCmdDG9CMzn68CGUI559292	rogid:/9rpwdudXQWv8z8JLmRecXf3YQM9606	intact-crc:D7ED7E4E6C45CA2B|rigid:gt8pj4ZDFSCdBUapixL/5NGgO+s	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9H190	uniprotkb:P32796	intact:EBI-742426|ensembl:ENSP00000371233|uniprotkb:O95892|uniprotkb:Q5W0X1|uniprotkb:Q9BZ42|uniprotkb:Q9H567|uniprotkb:Q9NRY8|intact:EBI-28983470|ensembl:ENSP00000342935|ensembl:ENSP00000354013	intact:EBI-3935|uniprotkb:D6VZD3|ensemblfungi:YML042W	psi-mi:sdcb2_human(display_long)|uniprotkb:Similar to TACIP18(gene name synonym)|uniprotkb:SDCBP2(gene name)|psi-mi:SDCBP2(display_short)|uniprotkb:SITAC18(gene name synonym)|uniprotkb:Syndecan-binding protein 2(gene name synonym)	psi-mi:cacp_yeast(display_long)|uniprotkb:CAT2(gene name)|psi-mi:CAT2(display_short)|uniprotkb:CAT(gene name synonym)|uniprotkb:YCAT(gene name synonym)|uniprotkb:YML042W(locus name)|uniprotkb:YM8054.01(orf name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11526804|imex:IM-24995-465	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001186713.1|refseq:NP_056500.2|refseq:NP_536737.3|ensembl:ENSP00000342935|ensembl:ENSP00000354013|ensembl:ENST00000381808|ensembl:ENSP00000371229|ensembl:ENSP00000371233|ensembl:ENSG00000125775(gene)|ensembl:ENST00000360779(transcript)|ensembl:ENST00000381812(transcript)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007399"(nervous system development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016607"(nuclear speck)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046907"(intracellular transport)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036034|interpro:IPR041489|ensembl:ENST00000339987(transcript)|entrezgene/locuslink:27111(identity)	refseq:NP_013670.1|sgd:S000004506|dip:DIP-2476N|reactome:R-SCE-1483191|reactome:R-SCE-264642|reactome:R-SCE-389887|reactome:R-SCE-9033241|ensemblfungi:YML042W(gene)|ensemblfungi:YML042W_mRNA(transcript)|go:"GO:0004092"(carnitine O-acetyltransferase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005777"(peroxisome)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0009437"(carnitine metabolic process)|interpro:IPR000542(Acyltransferase ChoActase/COT/CPT)|interpro:IPR023213|interpro:IPR039551|interpro:IPR042231|sgd:YML042W(identity)	-	-	crc64:C707BAC7ECB4D095	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:vlEtVZkwLTte5PJ4i8ce+SwE/4Y9606	rogid:2UCscm7QlYT+CY3gtU/Wg37C/+Y559292	intact-crc:F18C6D7B8811FD84|rigid:GebY+wTkfNrK55hJdHdAHIewoxc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32895	uniprotkb:P60891	intact:EBI-9869|uniprotkb:D6VX20|ensemblfungi:YKL181W	intact:EBI-749195|uniprotkb:P09329|uniprotkb:B2R6T7|uniprotkb:B1ALA8|uniprotkb:B4DNL6|uniprotkb:D3DUX6|ensembl:ENSP00000361512	psi-mi:kpr1_yeast(display_long)|uniprotkb:PPS1(gene name synonym)|uniprotkb:PRP1(gene name synonym)|uniprotkb:PRPS(gene name synonym)|uniprotkb:PRPS1(gene name synonym)|uniprotkb:YKL181W(locus name)|uniprotkb:PRS1(gene name)|psi-mi:PRS1(display_short)|uniprotkb:Phosphoribosyl pyrophosphate synthase 1(gene name synonym)	psi-mi:prps1_human(display_long)|uniprotkb:Phosphoribosyl pyrophosphate synthase I(gene name synonym)|uniprotkb:PRPS1(gene name)|psi-mi:PRPS1(display_short)|uniprotkb:PPRibP(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11526842|imex:IM-24995-469	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012740.1|sgd:S000001664|ensemblfungi:YKL181W(gene)|ensemblfungi:YKL181W_mRNA(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0002189"(ribose phosphate diphosphokinase complex)|go:"GO:0004749"(ribose phosphate diphosphokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006015"(5-phosphoribose 1-diphosphate biosynthetic process)|go:"GO:0006164"(purine nucleotide biosynthetic process)|go:"GO:0009116"(nucleoside metabolic process)|go:"GO:0009156"(ribonucleoside monophosphate biosynthetic process)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016301"(kinase activity)|go:"GO:0031505"(fungal-type cell wall organization)|interpro:IPR000836(Phosphoribosyltransferase)|interpro:IPR000842(Phosphoribosyl pyrophosphate synthetase, conserved site)|interpro:IPR005946(Phosphoribosyl pyrophosphokinase)|interpro:IPR029057|interpro:IPR029099|reactome:R-SCE-73843|dip:DIP-4857N|mint:P32895|sgd:YKL181W(identity)	refseq:NP_001191331.1|refseq:NP_002755.1|ensembl:ENSG00000147224(gene)|ensembl:ENST00000372435(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0002189"(ribose phosphate diphosphokinase complex)|go:"GO:0004749"(ribose phosphate diphosphokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006015"(5-phosphoribose 1-diphosphate biosynthetic process)|go:"GO:0006164"(purine nucleotide biosynthetic process)|go:"GO:0006221"(pyrimidine nucleotide biosynthetic process)|go:"GO:0007399"(nervous system development)|go:"GO:0009116"(nucleoside metabolic process)|go:"GO:0009156"(ribonucleoside monophosphate biosynthetic process)|go:"GO:0016301"(kinase activity)|go:"GO:0034418"(urate biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046101"(hypoxanthine biosynthetic process)|interpro:IPR000836(Phosphoribosyltransferase)|interpro:IPR000842(Phosphoribosyl pyrophosphate synthetase, conserved site)|interpro:IPR005946(Phosphoribosyl pyrophosphokinase)|go:"GO:0006144"(purine nucleobase metabolic process)|interpro:IPR029057|interpro:IPR029099|interpro:IPR037515|rcsb pdb:2H06|rcsb pdb:2H07|rcsb pdb:2H08|rcsb pdb:2HCR|rcsb pdb:3EFH|rcsb pdb:3S5J|rcsb pdb:4F8E|rcsb pdb:4LYG|rcsb pdb:4LZN|rcsb pdb:4LZO|rcsb pdb:4M0P|rcsb pdb:4M0U|reactome:R-HSA-73843|dip:DIP-61999N|entrezgene/locuslink:5631(identity)	-	crc64:F3E93ACB25E703FF	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Ea45pOje4sjYrrU7ze4Af443yDk559292	rogid:+Hih2M7JLTsjEglauBlPj182h9M9606	intact-crc:C6B1B9BF42553E37|rigid:3TY8kxFwrUo6RAg2bNdsrGenDxc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32831	uniprotkb:Q15427	intact:EBI-12002|ensemblfungi:YBR212W|uniprotkb:D6VQK8	intact:EBI-348469|ensembl:ENSP00000271628|intact:EBI-1047735|uniprotkb:Q5SZ63	psi-mi:ngr1_yeast(display_long)|uniprotkb:NGR1(gene name)|psi-mi:NGR1(display_short)|uniprotkb:RBP1(gene name synonym)|uniprotkb:YBR212W(locus name)|uniprotkb:YBR1459(orf name)|uniprotkb:RNA-binding protein RBP1(gene name synonym)	psi-mi:sf3b4_human(display_long)|uniprotkb:SF3B4(gene name)|psi-mi:SF3B4(display_short)|uniprotkb:SAP49(gene name synonym)|uniprotkb:Spliceosome-associated protein 49(gene name synonym)|uniprotkb:Pre-mRNA-splicing factor SF3b 49 kDa subunit(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11526824|imex:IM-24995-467	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YBR212W(gene)|ensemblfungi:YBR212W_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|refseq:NP_009771.3|sgd:S000000416|mint:P32831|dip:DIP-5160N|sgd:YBR212W(identity)	refseq:NP_005841.1|ensembl:ENSG00000143368(gene)|ensembl:ENST00000271628(transcript)|rcsb pdb:6QX9|rcsb pdb:6Y53|rcsb pdb:6Y5Q|rcsb pdb:7ABG|rcsb pdb:7ABH|rcsb pdb:7ABI|rcsb pdb:7DVQ|reactome:R-HSA-72163|reactome:R-HSA-72165|rcsb pdb:6AHD|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:1990935"(splicing factor binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034158|go:"GO:0000375"(RNA splicing, via transesterification reactions)|interpro:IPR034159|interpro:IPR035979|mint:Q15427|rcsb pdb:1X5T|rcsb pdb:5GVQ|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|entrezgene/locuslink:10262(identity)	-	crc64:12F64EC4C5716750	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:MCNbYrmWkUp7dAyKpebSKsIzOxA559292	rogid:Jgy6WmBFKkphpZLLte2GgsagUVI9606	intact-crc:BFE273B64D0BF92B|rigid:WSu9Xoaj+gpfen6jYmc5WJVxJlk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32844	uniprotkb:Q8N5R6	intact:EBI-16874|uniprotkb:D6VVL6|ensemblfungi:YIL068C	intact:EBI-740841|intact:EBI-953781|uniprotkb:B3KQ49|uniprotkb:A8K3U4|uniprotkb:A8MPQ6|uniprotkb:A8MV61|uniprotkb:A8MVU9|uniprotkb:Q9H5Q6|uniprotkb:Q8TAX6|intact:EBI-2320546|intact:EBI-11522976	psi-mi:sec6_yeast(display_long)|uniprotkb:YIL068C(locus name)|uniprotkb:SEC6(gene name)|psi-mi:SEC6(display_short)	psi-mi:ccd33_human(display_long)|uniprotkb:CCDC33(gene name)|psi-mi:CCDC33(display_short)|uniprotkb:Cancer/testis antigen 61(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11526833|imex:IM-24995-468	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012196.1|sgd:S000001330|ensemblfungi:YIL068C(gene)|ensemblfungi:YIL068C_mRNA(transcript)|go:"GO:0000145"(exocyst)|go:"GO:0000149"(SNARE binding)|go:"GO:0005628"(prospore membrane)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0015031"(protein transport)|go:"GO:0035544"(negative regulation of SNARE complex assembly)|go:"GO:0043332"(mating projection tip)|go:"GO:0051601"(exocyst localization)|go:"GO:0090522"(vesicle tethering involved in exocytosis)|interpro:IPR010326(Exocyst complex component Sec6)|interpro:IPR042532|rcsb pdb:2FJI|rcsb pdb:5YFP|rcsb pdb:6VKL|reactome:R-SCE-264876|dip:DIP-5649N|mint:P32844|sgd:YIL068C(identity)	refseq:NP_079331.3|interpro:IPR000008(C2 calcium-dependent membrane targeting)|go:"GO:0005777"(peroxisome)|refseq:NP_001274110.1|refseq:NP_877592.2|mint:Q8N5R6|interpro:IPR035892|interpro:IPR039889|entrezgene/locuslink:80125(identity)	-	crc64:2B09BBBE15389239	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2021/11/30	rogid:SJtUIHyBTy38oPOc0h4D3Anipvc559292	rogid:eEIn7pQyfdHWx8TeLJpYy0i/gww9606	intact-crc:3A390989D20C9456|rigid:x4nnJ1Ba4hXL5Wbd4a9rc+M/1as	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q7Z6G3-2	uniprotkb:P32902	intact:EBI-10172876|ensembl:ENSP00000457354|intact:EBI-14062040	intact:EBI-16248|ensemblfungi:YHL004W|uniprotkb:D3DKR0	psi-mi:q7z6g3-2(display_long)|uniprotkb:EFCBP2(gene name synonym)|uniprotkb:Neuronal calcium-binding protein 2(gene name synonym)|uniprotkb:Synaptotagmin-interacting protein 2(gene name synonym)|uniprotkb:NECAB2(gene name)|psi-mi:NECAB2(display_short)	psi-mi:rt04_yeast(display_long)|uniprotkb:MRP4(gene name)|psi-mi:MRP4(display_short)|uniprotkb:MRP4A(gene name synonym)|uniprotkb:Mitochondrial small ribosomal subunit protein uS2m(gene name synonym)|uniprotkb:YHL004W(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11526869|imex:IM-24995-472	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000103154(gene)|ensembl:ENST00000565691(transcript)|uniprotkb:Q7Z6G3-2(isoform-parent)|intact:EBI-950070(isoform-parent)|entrezgene/locuslink:54550(identity)	ensemblfungi:YHL004W(gene)|ensemblfungi:YHL004W_mRNA(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR001865(Ribosomal protein S2)|interpro:IPR005706(Ribosomal protein S2, bacterial-type)|interpro:IPR018130|interpro:IPR023591|rcsb pdb:5MRC|rcsb pdb:5MRE|rcsb pdb:5MRF|refseq:NP_011859.1|sgd:S000000996|dip:DIP-5035N|mint:P32902|sgd:YHL004W(identity)	-	-	crc64:81A1CB33134BC559	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:4S7oIx6h+mKzV3EPxqcfMNqaNko9606	rogid:BlL3W6HUN+uAKF/AxwlV1zT5YZQ559292	intact-crc:344E2A12102289CC|rigid:m58Zj9qZ8WkdvEdqLw8LDRMDctM	false	sufficient binding region:65-303	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q14558	uniprotkb:P32895	intact:EBI-724449|uniprotkb:Q96H06|uniprotkb:B2R6M4	intact:EBI-9869|uniprotkb:D6VX20|ensemblfungi:YKL181W	psi-mi:kpra_human(display_long)|uniprotkb:39 kDa phosphoribosypyrophosphate synthase-associated protein(gene name synonym)|uniprotkb:PRPSAP1(gene name)|psi-mi:PRPSAP1(display_short)	psi-mi:kpr1_yeast(display_long)|uniprotkb:PPS1(gene name synonym)|uniprotkb:PRP1(gene name synonym)|uniprotkb:PRPS(gene name synonym)|uniprotkb:PRPS1(gene name synonym)|uniprotkb:YKL181W(locus name)|uniprotkb:PRS1(gene name)|psi-mi:PRS1(display_short)|uniprotkb:Phosphoribosyl pyrophosphate synthase 1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11526851|imex:IM-24995-470	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002757.2|interpro:IPR005946(Phosphoribosyl pyrophosphokinase)|rcsb pdb:2C4K|go:"GO:0000287"(magnesium ion binding)|go:"GO:0002189"(ribose phosphate diphosphokinase complex)|go:"GO:0004749"(ribose phosphate diphosphokinase activity)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006015"(5-phosphoribose 1-diphosphate biosynthetic process)|go:"GO:0006139"(nucleobase-containing compound metabolic process)|go:"GO:0006164"(purine nucleotide biosynthetic process)|go:"GO:0042802"(identical protein binding)|interpro:IPR029057|interpro:IPR029099|entrezgene/locuslink:5635(identity)	refseq:NP_012740.1|sgd:S000001664|ensemblfungi:YKL181W(gene)|ensemblfungi:YKL181W_mRNA(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0002189"(ribose phosphate diphosphokinase complex)|go:"GO:0004749"(ribose phosphate diphosphokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006015"(5-phosphoribose 1-diphosphate biosynthetic process)|go:"GO:0006164"(purine nucleotide biosynthetic process)|go:"GO:0009116"(nucleoside metabolic process)|go:"GO:0009156"(ribonucleoside monophosphate biosynthetic process)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016301"(kinase activity)|go:"GO:0031505"(fungal-type cell wall organization)|interpro:IPR000836(Phosphoribosyltransferase)|interpro:IPR000842(Phosphoribosyl pyrophosphate synthetase, conserved site)|interpro:IPR005946(Phosphoribosyl pyrophosphokinase)|interpro:IPR029057|interpro:IPR029099|reactome:R-SCE-73843|dip:DIP-4857N|mint:P32895|sgd:YKL181W(identity)	-	-	crc64:F3E93ACB25E703FF	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:7kFJX6q/3EcGnRNgAOImlr93Xys9606	rogid:Ea45pOje4sjYrrU7ze4Af443yDk559292	intact-crc:78E27DA91D6B5A15|rigid:qvyrZ/jsfWNgyC6izWzv5pYzHE4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32902	intact:EBI-11525577	intact:EBI-16248|ensemblfungi:YHL004W|uniprotkb:D3DKR0	-	psi-mi:rt04_yeast(display_long)|uniprotkb:MRP4(gene name)|psi-mi:MRP4(display_short)|uniprotkb:MRP4A(gene name synonym)|uniprotkb:Mitochondrial small ribosomal subunit protein uS2m(gene name synonym)|uniprotkb:YHL004W(locus name)	psi-mi:pde4dip(display_short)|psi-mi:EBI-11525577(display_long)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11526860|imex:IM-24995-471	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YHL004W(gene)|ensemblfungi:YHL004W_mRNA(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR001865(Ribosomal protein S2)|interpro:IPR005706(Ribosomal protein S2, bacterial-type)|interpro:IPR018130|interpro:IPR023591|rcsb pdb:5MRC|rcsb pdb:5MRE|rcsb pdb:5MRF|refseq:NP_011859.1|sgd:S000000996|dip:DIP-5035N|mint:P32902|sgd:YHL004W(identity)	entrezgene/locuslink:9659(identity)	-	crc64:81A1CB33134BC559	no-uniprot-update:	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:BlL3W6HUN+uAKF/AxwlV1zT5YZQ559292	rogid:1FG5rtwoLqpyiNu81cqSpFdaXDY9606	intact-crc:7491D2445F2C8243|rigid:RLNKJwoWVyDqVcuX5iOyxTOx78U	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32902	uniprotkb:P36406	intact:EBI-16248|ensemblfungi:YHL004W|uniprotkb:D3DKR0	intact:EBI-740098|uniprotkb:Q9BZY4|uniprotkb:Q9BZY5|ensembl:ENSP00000231524	psi-mi:rt04_yeast(display_long)|uniprotkb:MRP4(gene name)|psi-mi:MRP4(display_short)|uniprotkb:MRP4A(gene name synonym)|uniprotkb:Mitochondrial small ribosomal subunit protein uS2m(gene name synonym)|uniprotkb:YHL004W(locus name)	psi-mi:tri23_human(display_long)|uniprotkb:TRIM23(gene name)|psi-mi:TRIM23(display_short)|uniprotkb:ARD1(gene name synonym)|uniprotkb:ARFD1(gene name synonym)|uniprotkb:RNF46(gene name synonym)|uniprotkb:ADP-ribosylation factor domain-containing protein 1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 23(gene name synonym)|uniprotkb:RING finger protein 46(gene name synonym)|uniprotkb:GTP-binding protein ARD-1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM23(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11526907|imex:IM-24995-476	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YHL004W(gene)|ensemblfungi:YHL004W_mRNA(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR001865(Ribosomal protein S2)|interpro:IPR005706(Ribosomal protein S2, bacterial-type)|interpro:IPR018130|interpro:IPR023591|rcsb pdb:5MRC|rcsb pdb:5MRE|rcsb pdb:5MRF|refseq:NP_011859.1|sgd:S000000996|dip:DIP-5035N|mint:P32902|sgd:YHL004W(identity)	refseq:NP_001647.1|refseq:NP_150230.1|refseq:NP_150231.1|refseq:XP_016864933.1|ensembl:ENSG00000113595(gene)|ensembl:ENST00000231524(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019003"(GDP binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR017907|interpro:IPR027417|mint:P36406|rcsb pdb:5VZV|rcsb pdb:5VZW|entrezgene/locuslink:373(identity)	-	crc64:81A1CB33134BC559	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:BlL3W6HUN+uAKF/AxwlV1zT5YZQ559292	rogid:skGAO7nm9YvqJGWF6fzjtn5CWuc9606	intact-crc:715F36290B7F63F9|rigid:B+YCiMtTsROETnJFJlOLGrc0lvM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32902	uniprotkb:O95273	intact:EBI-16248|ensemblfungi:YHL004W|uniprotkb:D3DKR0	intact:EBI-748961|uniprotkb:A8K3Q0|uniprotkb:A8K3U2|uniprotkb:Q6ZQN9|uniprotkb:Q7Z519|uniprotkb:Q8NBS7|uniprotkb:Q8NBY2|uniprotkb:Q9NS19|uniprotkb:Q9NYH3|uniprotkb:Q9UHX9|ensembl:ENSP00000300213	psi-mi:rt04_yeast(display_long)|uniprotkb:MRP4(gene name)|psi-mi:MRP4(display_short)|uniprotkb:MRP4A(gene name synonym)|uniprotkb:Mitochondrial small ribosomal subunit protein uS2m(gene name synonym)|uniprotkb:YHL004W(locus name)	psi-mi:ccdb1_human(display_long)|uniprotkb:Grap2 and cyclin-D-interacting protein(gene name synonym)|uniprotkb:Human homolog of Maid(gene name synonym)|uniprotkb:CCNDBP1(gene name)|psi-mi:CCNDBP1(display_short)|uniprotkb:DIP1(gene name synonym)|uniprotkb:GCIP(gene name synonym)|uniprotkb:HHM(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11526880|imex:IM-24995-473	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YHL004W(gene)|ensemblfungi:YHL004W_mRNA(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR001865(Ribosomal protein S2)|interpro:IPR005706(Ribosomal protein S2, bacterial-type)|interpro:IPR018130|interpro:IPR023591|rcsb pdb:5MRC|rcsb pdb:5MRE|rcsb pdb:5MRF|refseq:NP_011859.1|sgd:S000000996|dip:DIP-5035N|mint:P32902|sgd:YHL004W(identity)	refseq:NP_036274.3|ensembl:ENSG00000166946(gene)|ensembl:ENST00000300213(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0016604"(nuclear body)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR026907|mint:O95273|rcsb pdb:3AY5|entrezgene/locuslink:23582(identity)	-	crc64:81A1CB33134BC559	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:BlL3W6HUN+uAKF/AxwlV1zT5YZQ559292	rogid:Vi9aoFc+Mov6P3X6KGmsTxXqxvM9606	intact-crc:C6F4D970A6CE7997|rigid:BDD/Zudt6reIXIk4+QnpoexF8Bc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O95751	uniprotkb:P32902	intact:EBI-740738|ensembl:ENSP00000359557|uniprotkb:Q6IAR6	intact:EBI-16248|ensemblfungi:YHL004W|uniprotkb:D3DKR0	psi-mi:ldoc1_human(display_long)|uniprotkb:Leucine zipper protein down-regulated in cancer cells(gene name synonym)|uniprotkb:LDOC1(gene name)|psi-mi:LDOC1(display_short)|uniprotkb:BCUR1(gene name synonym)	psi-mi:rt04_yeast(display_long)|uniprotkb:MRP4(gene name)|psi-mi:MRP4(display_short)|uniprotkb:MRP4A(gene name synonym)|uniprotkb:Mitochondrial small ribosomal subunit protein uS2m(gene name synonym)|uniprotkb:YHL004W(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11526889|imex:IM-24995-474	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_036449.1|ensembl:ENSG00000182195(gene)|ensembl:ENST00000370526(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071225"(cellular response to muramyl dipeptide)|interpro:IPR032549|interpro:IPR032567|entrezgene/locuslink:23641(identity)	ensemblfungi:YHL004W(gene)|ensemblfungi:YHL004W_mRNA(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR001865(Ribosomal protein S2)|interpro:IPR005706(Ribosomal protein S2, bacterial-type)|interpro:IPR018130|interpro:IPR023591|rcsb pdb:5MRC|rcsb pdb:5MRE|rcsb pdb:5MRF|refseq:NP_011859.1|sgd:S000000996|dip:DIP-5035N|mint:P32902|sgd:YHL004W(identity)	-	-	crc64:81A1CB33134BC559	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Ediu0oNiZ/+YVY8l3fNdgP5A+v09606	rogid:BlL3W6HUN+uAKF/AxwlV1zT5YZQ559292	intact-crc:FE1BD2E1B56276EA|rigid:3j66pJ42LxFcWILS+fD3GiJbTE4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32902	uniprotkb:P13196	intact:EBI-16248|ensemblfungi:YHL004W|uniprotkb:D3DKR0	intact:EBI-3905054|ensembl:ENSP00000309259|ensembl:ENSP00000378416|ensembl:ENSP00000417719|ensembl:ENSP00000418779	psi-mi:rt04_yeast(display_long)|uniprotkb:MRP4(gene name)|psi-mi:MRP4(display_short)|uniprotkb:MRP4A(gene name synonym)|uniprotkb:Mitochondrial small ribosomal subunit protein uS2m(gene name synonym)|uniprotkb:YHL004W(locus name)	psi-mi:hem1_human(display_long)|uniprotkb:ALAS1(gene name)|psi-mi:ALAS1(display_short)|uniprotkb:ALAS3(gene name synonym)|uniprotkb:ALASH(gene name synonym)|uniprotkb:5-aminolevulinic acid synthase 1(gene name synonym)|uniprotkb:Delta-ALA synthase 1(gene name synonym)|uniprotkb:Delta-aminolevulinate synthase 1(gene name synonym)|uniprotkb:OK/SW-cl.121(orf name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11526898|imex:IM-24995-475	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YHL004W(gene)|ensemblfungi:YHL004W_mRNA(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR001865(Ribosomal protein S2)|interpro:IPR005706(Ribosomal protein S2, bacterial-type)|interpro:IPR018130|interpro:IPR023591|rcsb pdb:5MRC|rcsb pdb:5MRE|rcsb pdb:5MRF|refseq:NP_011859.1|sgd:S000000996|dip:DIP-5035N|mint:P32902|sgd:YHL004W(identity)	refseq:NP_001291372.1|refseq:NP_001291373.1|refseq:NP_000679.1|refseq:NP_954635.1|go:"GO:0006783"(heme biosynthetic process)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0042541"(hemoglobin biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0048821"(erythrocyte development)|ensembl:ENSG00000023330(gene)|ensembl:ENST00000310271(transcript)|ensembl:ENST00000394965(transcript)|ensembl:ENST00000469224(transcript)|ensembl:ENST00000484952(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0003870"(5-aminolevulinate synthase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|interpro:IPR001917(Aminotransferase, class-II, pyridoxal-phosphate binding site)|interpro:IPR004839(Aminotransferase, class I and II)|interpro:IPR010961(Tetrapyrrole biosynthesis, 5-aminolevulinic acid synthase)|interpro:IPR015118(5-aminolevulinate synthase presequence)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|mint:P13196|reactome:R-HSA-189451|reactome:R-HSA-1989781|reactome:R-HSA-2151201|go:"GO:0006782"(protoporphyrinogen IX biosynthetic process)|entrezgene/locuslink:211(identity)	-	crc64:81A1CB33134BC559	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:BlL3W6HUN+uAKF/AxwlV1zT5YZQ559292	rogid:HFjJ6zrRF9UYD7LMB6A3CcxcS7c9606	intact-crc:CB016CCE144D9C30|rigid:hNk4Ti++B/6J9ajZ8u5eL5h10cY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32902	uniprotkb:Q5JR59-3	intact:EBI-16248|ensemblfungi:YHL004W|uniprotkb:D3DKR0	intact:EBI-11522433|ensembl:ENSP00000370186	psi-mi:rt04_yeast(display_long)|uniprotkb:MRP4(gene name)|psi-mi:MRP4(display_short)|uniprotkb:MRP4A(gene name synonym)|uniprotkb:Mitochondrial small ribosomal subunit protein uS2m(gene name synonym)|uniprotkb:YHL004W(locus name)	psi-mi:q5jr59-3(display_long)|uniprotkb:MTUS2(gene name)|psi-mi:MTUS2(display_short)|uniprotkb:CAZIP(gene name synonym)|uniprotkb:Cardiac zipper protein(gene name synonym)|uniprotkb:KIAA0774(gene name synonym)|uniprotkb:Microtubule plus-end tracking protein TIP150(gene name synonym)|uniprotkb:TIP150(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11526934|imex:IM-24995-479	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YHL004W(gene)|ensemblfungi:YHL004W_mRNA(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR001865(Ribosomal protein S2)|interpro:IPR005706(Ribosomal protein S2, bacterial-type)|interpro:IPR018130|interpro:IPR023591|rcsb pdb:5MRC|rcsb pdb:5MRE|rcsb pdb:5MRF|refseq:NP_011859.1|sgd:S000000996|dip:DIP-5035N|mint:P32902|sgd:YHL004W(identity)	ensembl:ENSG00000132938(gene)|ensembl:ENST00000380808(transcript)|intact:EBI-742948(isoform-parent)|uniprotkb:Q5JR59-3(isoform-parent)|entrezgene/locuslink:23281(identity)	-	crc64:81A1CB33134BC559	isoform-comment:No experimental confirmation available.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:BlL3W6HUN+uAKF/AxwlV1zT5YZQ559292	rogid:npId9tC7VoLN/jteoBiRbSYChPs9606	intact-crc:DD0FECBDB915E2CC|rigid:SUqmciFNzecgze196/COIEQtPY0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32902	uniprotkb:Q5T124-6	intact:EBI-16248|ensemblfungi:YHL004W|uniprotkb:D3DKR0	intact:EBI-11524408	psi-mi:rt04_yeast(display_long)|uniprotkb:MRP4(gene name)|psi-mi:MRP4(display_short)|uniprotkb:MRP4A(gene name synonym)|uniprotkb:Mitochondrial small ribosomal subunit protein uS2m(gene name synonym)|uniprotkb:YHL004W(locus name)	psi-mi:q5t124-6(display_long)|uniprotkb:UBXN11(gene name)|psi-mi:UBXN11(display_short)|uniprotkb:Colorectal tumor-associated antigen COA-1(gene name synonym)|uniprotkb:SOC(gene name synonym)|uniprotkb:Socius(gene name synonym)|uniprotkb:UBX domain-containing protein 5(gene name synonym)|uniprotkb:UBXD5(gene name synonym)|uniprotkb:PP2243(orf name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11526943|imex:IM-24995-480	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YHL004W(gene)|ensemblfungi:YHL004W_mRNA(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR001865(Ribosomal protein S2)|interpro:IPR005706(Ribosomal protein S2, bacterial-type)|interpro:IPR018130|interpro:IPR023591|rcsb pdb:5MRC|rcsb pdb:5MRE|rcsb pdb:5MRF|refseq:NP_011859.1|sgd:S000000996|dip:DIP-5035N|mint:P32902|sgd:YHL004W(identity)	intact:EBI-746004(isoform-parent)|uniprotkb:Q5T124-6(isoform-parent)|entrezgene/locuslink:91544(identity)	-	crc64:81A1CB33134BC559	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:BlL3W6HUN+uAKF/AxwlV1zT5YZQ559292	rogid:1YSjG/p2ihcjl4P8KdPCaX2HxiY9606	intact-crc:89E417C14CC8FF6D|rigid:Rn3lxpxa/3W/L2hcoFjM/QSt1G4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32902	uniprotkb:P43361	intact:EBI-16248|ensemblfungi:YHL004W|uniprotkb:D3DKR0	intact:EBI-10182930|uniprotkb:Q9BUN9|intact:EBI-28989087|ensembl:ENSP00000286482|ensembl:ENSP00000438293|ensembl:ENSP00000443776	psi-mi:rt04_yeast(display_long)|uniprotkb:MRP4(gene name)|psi-mi:MRP4(display_short)|uniprotkb:MRP4A(gene name synonym)|uniprotkb:Mitochondrial small ribosomal subunit protein uS2m(gene name synonym)|uniprotkb:YHL004W(locus name)	psi-mi:maga8_human(display_long)|uniprotkb:MAGEA8(gene name)|psi-mi:MAGEA8(display_short)|uniprotkb:Cancer/testis antigen 1.8(gene name synonym)|uniprotkb:MAGE-8 antigen(gene name synonym)|uniprotkb:MAGE8(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11526916|imex:IM-24995-477	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YHL004W(gene)|ensemblfungi:YHL004W_mRNA(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR001865(Ribosomal protein S2)|interpro:IPR005706(Ribosomal protein S2, bacterial-type)|interpro:IPR018130|interpro:IPR023591|rcsb pdb:5MRC|rcsb pdb:5MRE|rcsb pdb:5MRF|refseq:NP_011859.1|sgd:S000000996|dip:DIP-5035N|mint:P32902|sgd:YHL004W(identity)	refseq:NP_001159872.1|refseq:NP_001159873.1|refseq:NP_005355.2|refseq:XP_016885009.1|ensembl:ENSP00000286482|ensembl:ENSP00000438293|ensembl:ENSP00000443776|ensembl:ENSG00000156009(gene)|ensembl:ENST00000286482(transcript)|ensembl:ENST00000535454(transcript)|ensembl:ENST00000542674(transcript)|interpro:IPR002190(MAGE protein)|interpro:IPR021072|interpro:IPR030095|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|entrezgene/locuslink:4107(identity)	-	crc64:81A1CB33134BC559	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:BlL3W6HUN+uAKF/AxwlV1zT5YZQ559292	rogid:Qz29eM5nzFfUZl/DBtBcdhGQBNE9606	intact-crc:4850B083BAE8559A|rigid:VTbvHt8oLrIEYWwXe7e88GF4gGE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32902	uniprotkb:Q13137	intact:EBI-16248|ensemblfungi:YHL004W|uniprotkb:D3DKR0	intact:EBI-739580|uniprotkb:B4DDC4|uniprotkb:E7ENK0|uniprotkb:Q53FQ5|uniprotkb:Q53HB5|uniprotkb:Q6IBN9|uniprotkb:Q9BTF7|uniprotkb:B2RBT0|ensembl:ENSP00000258947|uniprotkb:B4E0C0|uniprotkb:E7ETP5|uniprotkb:B4DDT4|uniprotkb:B4DP36|uniprotkb:E9PBE5	psi-mi:rt04_yeast(display_long)|uniprotkb:MRP4(gene name)|psi-mi:MRP4(display_short)|uniprotkb:MRP4A(gene name synonym)|uniprotkb:Mitochondrial small ribosomal subunit protein uS2m(gene name synonym)|uniprotkb:YHL004W(locus name)	psi-mi:caco2_human(display_long)|uniprotkb:CALCOCO2(gene name)|psi-mi:CALCOCO2(display_short)|uniprotkb:NDP52(gene name synonym)|uniprotkb:Nuclear domain 10 protein NDP52(gene name synonym)|uniprotkb:Antigen nuclear dot 52 kDa protein(gene name synonym)|uniprotkb:Nuclear dot protein 52(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11526925|imex:IM-24995-478	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YHL004W(gene)|ensemblfungi:YHL004W_mRNA(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR001865(Ribosomal protein S2)|interpro:IPR005706(Ribosomal protein S2, bacterial-type)|interpro:IPR018130|interpro:IPR023591|rcsb pdb:5MRC|rcsb pdb:5MRE|rcsb pdb:5MRF|refseq:NP_011859.1|sgd:S000000996|dip:DIP-5035N|mint:P32902|sgd:YHL004W(identity)	refseq:NP_001248319.1|refseq:NP_001248320.1|refseq:NP_001248322.1|refseq:NP_005822.1|ensembl:ENSG00000136436(gene)|ensembl:ENST00000258947(transcript)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016032"(viral process)|go:"GO:0016605"(PML body)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0098792"(xenophagy)|go:"GO:1901098"(positive regulation of autophagosome maturation)|interpro:IPR041611|interpro:IPR041641|mint:Q13137|rcsb pdb:2MXP|rcsb pdb:3VVV|rcsb pdb:3VVW|rcsb pdb:4GXL|rcsb pdb:4HAN|rcsb pdb:4XKL|rcsb pdb:5AAQ|rcsb pdb:5Z7A|rcsb pdb:5Z7L|refseq:NP_001248324.1|dip:DIP-57534N|entrezgene/locuslink:10241(identity)	-	crc64:81A1CB33134BC559	crc64:609B121DA1A9DCB8	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:BlL3W6HUN+uAKF/AxwlV1zT5YZQ559292	rogid:N/GPJUGBK+Dh5Cg+csmafphuo9M9606	intact-crc:7E39083666E1B448|rigid:4ZnZLADDPmSwFQZcdVxBb3YFxqI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8NA61-2	uniprotkb:P32902	intact:EBI-11524851|ensembl:ENSP00000368249|ensembl:ENSP00000480148	intact:EBI-16248|ensemblfungi:YHL004W|uniprotkb:D3DKR0	psi-mi:q8na61-2(display_long)|uniprotkb:CBY2(gene name)|psi-mi:CBY2(display_short)|uniprotkb:SPERT(gene name synonym)|uniprotkb:Spermatid-associated protein(gene name synonym)	psi-mi:rt04_yeast(display_long)|uniprotkb:MRP4(gene name)|psi-mi:MRP4(display_short)|uniprotkb:MRP4A(gene name synonym)|uniprotkb:Mitochondrial small ribosomal subunit protein uS2m(gene name synonym)|uniprotkb:YHL004W(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11526972|imex:IM-24995-483	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-741724(isoform-parent)|ensembl:ENSG00000174015(gene)|ensembl:ENST00000378966(transcript)|ensembl:ENST00000610924(transcript)|uniprotkb:Q8NA61-2(isoform-parent)|entrezgene/locuslink:220082(identity)	ensemblfungi:YHL004W(gene)|ensemblfungi:YHL004W_mRNA(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR001865(Ribosomal protein S2)|interpro:IPR005706(Ribosomal protein S2, bacterial-type)|interpro:IPR018130|interpro:IPR023591|rcsb pdb:5MRC|rcsb pdb:5MRE|rcsb pdb:5MRF|refseq:NP_011859.1|sgd:S000000996|dip:DIP-5035N|mint:P32902|sgd:YHL004W(identity)	-	-	crc64:81A1CB33134BC559	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:SogYcXGGMYRYzB9xKC5o0pEtsDs9606	rogid:BlL3W6HUN+uAKF/AxwlV1zT5YZQ559292	intact-crc:493AA96A6D593FE6|rigid:efXubap58mIr57EWgtd3RkV3SoM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32902	uniprotkb:Q8IYF3-3	intact:EBI-16248|ensemblfungi:YHL004W|uniprotkb:D3DKR0	intact:EBI-11523345|ensembl:ENSP00000363453	psi-mi:rt04_yeast(display_long)|uniprotkb:MRP4(gene name)|psi-mi:MRP4(display_short)|uniprotkb:MRP4A(gene name synonym)|uniprotkb:Mitochondrial small ribosomal subunit protein uS2m(gene name synonym)|uniprotkb:YHL004W(locus name)	psi-mi:q8iyf3-3(display_long)|uniprotkb:TEX11(gene name)|psi-mi:TEX11(display_short)|uniprotkb:Protein ZIP4 homolog(gene name synonym)|uniprotkb:ZIP4(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11526952|imex:IM-24995-481	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YHL004W(gene)|ensemblfungi:YHL004W_mRNA(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR001865(Ribosomal protein S2)|interpro:IPR005706(Ribosomal protein S2, bacterial-type)|interpro:IPR018130|interpro:IPR023591|rcsb pdb:5MRC|rcsb pdb:5MRE|rcsb pdb:5MRF|refseq:NP_011859.1|sgd:S000000996|dip:DIP-5035N|mint:P32902|sgd:YHL004W(identity)	ensembl:ENSG00000120498(gene)|ensembl:ENST00000374333(transcript)|intact:EBI-742397(isoform-parent)|uniprotkb:Q8IYF3-3(isoform-parent)|entrezgene/locuslink:56159(identity)	-	crc64:81A1CB33134BC559	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:BlL3W6HUN+uAKF/AxwlV1zT5YZQ559292	rogid:PUAMFmnm5ZV2rnJ1rhm9ZeRCixg9606	intact-crc:427C47A59B780925|rigid:5O6jZs2BB4nz3YQQSmrfCo54JsY	false	-	sufficient binding region:9-925	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8N6Y0	uniprotkb:P32902	intact:EBI-739895|uniprotkb:Q8NBX7|uniprotkb:Q96KH3|uniprotkb:Q9BYI8|uniprotkb:A8K7L6|uniprotkb:B2RCR9|ensembl:ENSP00000252597	intact:EBI-16248|ensemblfungi:YHL004W|uniprotkb:D3DKR0	psi-mi:usbp1_human(display_long)|uniprotkb:USHBP1(gene name)|psi-mi:USHBP1(display_short)|uniprotkb:MCC-2(gene name synonym)|uniprotkb:AIE-75-binding protein(gene name synonym)|uniprotkb:AIEBP(gene name synonym)|uniprotkb:MCC2(gene name synonym)|uniprotkb:Mutated in colon cancer protein 2(gene name synonym)	psi-mi:rt04_yeast(display_long)|uniprotkb:MRP4(gene name)|psi-mi:MRP4(display_short)|uniprotkb:MRP4A(gene name synonym)|uniprotkb:Mitochondrial small ribosomal subunit protein uS2m(gene name synonym)|uniprotkb:YHL004W(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11526963|imex:IM-24995-482	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001284632.1|refseq:NP_114147.2|refseq:NP_001308346.1|ensembl:ENSG00000130307(gene)|ensembl:ENST00000252597(transcript)|go:"GO:0030165"(PDZ domain binding)|interpro:IPR019536|interpro:IPR040171|entrezgene/locuslink:83878(identity)	ensemblfungi:YHL004W(gene)|ensemblfungi:YHL004W_mRNA(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR001865(Ribosomal protein S2)|interpro:IPR005706(Ribosomal protein S2, bacterial-type)|interpro:IPR018130|interpro:IPR023591|rcsb pdb:5MRC|rcsb pdb:5MRE|rcsb pdb:5MRF|refseq:NP_011859.1|sgd:S000000996|dip:DIP-5035N|mint:P32902|sgd:YHL004W(identity)	-	-	crc64:81A1CB33134BC559	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:vY1qx73Ju/z7WDu6k1kd10ZDVRo9606	rogid:BlL3W6HUN+uAKF/AxwlV1zT5YZQ559292	intact-crc:1690024577367EBC|rigid:UpZ7rQV1DYkju5zEWzt11XSJgZ0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q93062-3	uniprotkb:P32902	intact:EBI-740343|ensembl:ENSP00000340176	intact:EBI-16248|ensemblfungi:YHL004W|uniprotkb:D3DKR0	psi-mi:q93062-3(display_long)|uniprotkb:RBPMS(gene name)|psi-mi:RBPMS(display_short)|uniprotkb:HERMES(gene name synonym)|uniprotkb:Heart and RRM expressed sequence(gene name synonym)	psi-mi:rt04_yeast(display_long)|uniprotkb:MRP4(gene name)|psi-mi:MRP4(display_short)|uniprotkb:MRP4A(gene name synonym)|uniprotkb:Mitochondrial small ribosomal subunit protein uS2m(gene name synonym)|uniprotkb:YHL004W(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11527008|imex:IM-24995-487	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-740322(rbpms_human)|uniprotkb:Q93062-3(isoform-parent)|ensembl:ENSG00000157110(gene)|ensembl:ENST00000339877(transcript)|entrezgene/locuslink:11030(identity)	ensemblfungi:YHL004W(gene)|ensemblfungi:YHL004W_mRNA(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR001865(Ribosomal protein S2)|interpro:IPR005706(Ribosomal protein S2, bacterial-type)|interpro:IPR018130|interpro:IPR023591|rcsb pdb:5MRC|rcsb pdb:5MRE|rcsb pdb:5MRF|refseq:NP_011859.1|sgd:S000000996|dip:DIP-5035N|mint:P32902|sgd:YHL004W(identity)	-	-	crc64:81A1CB33134BC559	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:nlPMQAJoKEbPYBwsL3xodmCKd7c9606	rogid:BlL3W6HUN+uAKF/AxwlV1zT5YZQ559292	intact-crc:8980739CA88A2EEE|rigid:mOQLEyFM/aDCReQLyjzL2d09iKY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8NHQ1	uniprotkb:P32902	intact:EBI-739624|ensembl:ENSP00000264982|ensembl:ENSP00000419231|uniprotkb:Q96B31|uniprotkb:Q9H2C3|uniprotkb:Q9H2Z1|uniprotkb:Q9H940|uniprotkb:D3DNE9|uniprotkb:B7Z5I8|uniprotkb:B7Z7E8|uniprotkb:F5GZX8	intact:EBI-16248|ensemblfungi:YHL004W|uniprotkb:D3DKR0	psi-mi:cep70_human(display_long)|uniprotkb:CEP70(gene name)|psi-mi:CEP70(display_short)|uniprotkb:BITE(gene name synonym)|uniprotkb:p10-binding protein(gene name synonym)	psi-mi:rt04_yeast(display_long)|uniprotkb:MRP4(gene name)|psi-mi:MRP4(display_short)|uniprotkb:MRP4A(gene name synonym)|uniprotkb:Mitochondrial small ribosomal subunit protein uS2m(gene name synonym)|uniprotkb:YHL004W(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11526981|imex:IM-24995-484	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114107(gene)|ensembl:ENST00000264982(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|interpro:IPR019734|interpro:IPR037692|mint:Q8NHQ1|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|ensembl:ENST00000484888(transcript)|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_077817.2|refseq:XP_016862764.1|refseq:NP_001275893.1|refseq:NP_001275894.1|refseq:NP_001275895.1|refseq:NP_001275896.1|refseq:NP_001307527.1|refseq:NP_001307529.1|entrezgene/locuslink:80321(identity)	ensemblfungi:YHL004W(gene)|ensemblfungi:YHL004W_mRNA(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR001865(Ribosomal protein S2)|interpro:IPR005706(Ribosomal protein S2, bacterial-type)|interpro:IPR018130|interpro:IPR023591|rcsb pdb:5MRC|rcsb pdb:5MRE|rcsb pdb:5MRF|refseq:NP_011859.1|sgd:S000000996|dip:DIP-5035N|mint:P32902|sgd:YHL004W(identity)	-	-	crc64:81A1CB33134BC559	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:S4yveQWcvdVtAUX65gqrJ5Dv0Mc9606	rogid:BlL3W6HUN+uAKF/AxwlV1zT5YZQ559292	intact-crc:B7246E4131D847E2|rigid:J2sM+DbG+y7tjVL8ykgESazQzJQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8WWB3	uniprotkb:P32902	intact:EBI-740680|ensembl:ENSP00000361276|ensembl:ENSP00000361278|ensembl:ENSP00000402890|uniprotkb:Q5QP03|uniprotkb:Q5QP04|uniprotkb:Q6WNP4|uniprotkb:Q6ZU87|uniprotkb:A8K927	intact:EBI-16248|ensemblfungi:YHL004W|uniprotkb:D3DKR0	psi-mi:dydc1_human(display_long)|uniprotkb:DYDC1(gene name)|psi-mi:DYDC1(display_short)|uniprotkb:DPY30D1(gene name synonym)|uniprotkb:RSD9(orf name)|uniprotkb:RSD-9(orf name)	psi-mi:rt04_yeast(display_long)|uniprotkb:MRP4(gene name)|psi-mi:MRP4(display_short)|uniprotkb:MRP4A(gene name synonym)|uniprotkb:Mitochondrial small ribosomal subunit protein uS2m(gene name synonym)|uniprotkb:YHL004W(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11526990|imex:IM-24995-485	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_620167.1|ensembl:ENSG00000170788(gene)|ensembl:ENST00000372202(transcript)|ensembl:ENST00000372204(transcript)|ensembl:ENST00000421924(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0006348"|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|interpro:IPR007858(Dpy-30)|interpro:IPR037856|refseq:XP_011537636.1|refseq:XP_011537637.1|refseq:NP_001255982.1|refseq:XP_005269606.1|refseq:XP_005269607.1|entrezgene/locuslink:143241(identity)	ensemblfungi:YHL004W(gene)|ensemblfungi:YHL004W_mRNA(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR001865(Ribosomal protein S2)|interpro:IPR005706(Ribosomal protein S2, bacterial-type)|interpro:IPR018130|interpro:IPR023591|rcsb pdb:5MRC|rcsb pdb:5MRE|rcsb pdb:5MRF|refseq:NP_011859.1|sgd:S000000996|dip:DIP-5035N|mint:P32902|sgd:YHL004W(identity)	-	-	crc64:81A1CB33134BC559	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:W6GUazYFXZGHGijUBpAJ5GiRuXA9606	rogid:BlL3W6HUN+uAKF/AxwlV1zT5YZQ559292	intact-crc:5A2C9D83D4E2E224|rigid:WzjHYqsDg3w44cS5krinjUt9vpI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32902	uniprotkb:Q8WXE1-3	intact:EBI-16248|ensemblfungi:YHL004W|uniprotkb:D3DKR0	intact:EBI-11524582|ensembl:ENSP00000400930	psi-mi:rt04_yeast(display_long)|uniprotkb:MRP4(gene name)|psi-mi:MRP4(display_short)|uniprotkb:MRP4A(gene name synonym)|uniprotkb:Mitochondrial small ribosomal subunit protein uS2m(gene name synonym)|uniprotkb:YHL004W(locus name)	psi-mi:q8wxe1-3(display_long)|uniprotkb:ATRIP(gene name)|psi-mi:ATRIP(display_short)|uniprotkb:AGS1(gene name synonym)|uniprotkb:ATM and Rad3-related-interacting protein(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11526999|imex:IM-24995-486	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YHL004W(gene)|ensemblfungi:YHL004W_mRNA(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR001865(Ribosomal protein S2)|interpro:IPR005706(Ribosomal protein S2, bacterial-type)|interpro:IPR018130|interpro:IPR023591|rcsb pdb:5MRC|rcsb pdb:5MRE|rcsb pdb:5MRF|refseq:NP_011859.1|sgd:S000000996|dip:DIP-5035N|mint:P32902|sgd:YHL004W(identity)	intact:EBI-747353(isoform-parent)|ensembl:ENSG00000164053(gene)|ensembl:ENST00000412052(transcript)|entrezgene/locuslink:84126(identity)	-	crc64:81A1CB33134BC559	isoform-comment:No experimental confirmation available.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:BlL3W6HUN+uAKF/AxwlV1zT5YZQ559292	rogid:NKCjy1jGZEySEhUOf8rJ6h9pyxY9606	intact-crc:C62DE7B3914EFFD1|rigid:q4kObxihjWSQ6C9C1opduIO+Xp0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96KN7-4	uniprotkb:P32902	intact:EBI-11525164|ensembl:ENSP00000372391	intact:EBI-16248|ensemblfungi:YHL004W|uniprotkb:D3DKR0	psi-mi:q96kn7-4(display_long)|uniprotkb:RPGRIP1(gene name)|psi-mi:RPGRIP1(display_short)	psi-mi:rt04_yeast(display_long)|uniprotkb:MRP4(gene name)|psi-mi:MRP4(display_short)|uniprotkb:MRP4A(gene name synonym)|uniprotkb:Mitochondrial small ribosomal subunit protein uS2m(gene name synonym)|uniprotkb:YHL004W(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11527035|imex:IM-24995-490	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-1050213(isoform-parent)|ensembl:ENSG00000092200(gene)|ensembl:ENST00000382933(transcript)|uniprotkb:Q96KN7-4(isoform-parent)|entrezgene/locuslink:57096(identity)	ensemblfungi:YHL004W(gene)|ensemblfungi:YHL004W_mRNA(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR001865(Ribosomal protein S2)|interpro:IPR005706(Ribosomal protein S2, bacterial-type)|interpro:IPR018130|interpro:IPR023591|rcsb pdb:5MRC|rcsb pdb:5MRE|rcsb pdb:5MRF|refseq:NP_011859.1|sgd:S000000996|dip:DIP-5035N|mint:P32902|sgd:YHL004W(identity)	-	-	crc64:81A1CB33134BC559	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Xy0433uM/nWhWLM/EsfESPJDIy49606	rogid:BlL3W6HUN+uAKF/AxwlV1zT5YZQ559292	intact-crc:925ED22EAA205FD7|rigid:XlxHB0UGXHGaHmIOBTNAOgoMUEc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96ED9-2	uniprotkb:P32902	intact:EBI-10961706|ensembl:ENSP00000264827	intact:EBI-16248|ensemblfungi:YHL004W|uniprotkb:D3DKR0	psi-mi:q96ed9-2(display_long)|uniprotkb:HOOK2(gene name)|psi-mi:HOOK2(display_short)	psi-mi:rt04_yeast(display_long)|uniprotkb:MRP4(gene name)|psi-mi:MRP4(display_short)|uniprotkb:MRP4A(gene name synonym)|uniprotkb:Mitochondrial small ribosomal subunit protein uS2m(gene name synonym)|uniprotkb:YHL004W(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11527017|imex:IM-24995-488	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000095066(gene)|ensembl:ENST00000264827(transcript)|intact:EBI-743290(isoform-parent)|uniprotkb:Q96ED9-2(isoform-parent)|entrezgene/locuslink:29911(identity)	ensemblfungi:YHL004W(gene)|ensemblfungi:YHL004W_mRNA(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR001865(Ribosomal protein S2)|interpro:IPR005706(Ribosomal protein S2, bacterial-type)|interpro:IPR018130|interpro:IPR023591|rcsb pdb:5MRC|rcsb pdb:5MRE|rcsb pdb:5MRF|refseq:NP_011859.1|sgd:S000000996|dip:DIP-5035N|mint:P32902|sgd:YHL004W(identity)	-	-	crc64:81A1CB33134BC559	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:aJZ/iDJpRk5dFL1NiouLuTjnOnc9606	rogid:BlL3W6HUN+uAKF/AxwlV1zT5YZQ559292	intact-crc:5D6F08925ED5E737|rigid:mdXrbh47M7UccastJZrUUg9uqFo	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96HT8	uniprotkb:P32902	intact:EBI-748896|uniprotkb:Q6NXT8|uniprotkb:Q9P0J5|uniprotkb:B2R6R0|ensembl:ENSP00000318154	intact:EBI-16248|ensemblfungi:YHL004W|uniprotkb:D3DKR0	psi-mi:mr1l1_human(display_long)|uniprotkb:PP784(orf name)|uniprotkb:MRFAP1L1(gene name)|psi-mi:MRFAP1L1(display_short)	psi-mi:rt04_yeast(display_long)|uniprotkb:MRP4(gene name)|psi-mi:MRP4(display_short)|uniprotkb:MRP4A(gene name synonym)|uniprotkb:Mitochondrial small ribosomal subunit protein uS2m(gene name synonym)|uniprotkb:YHL004W(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11527026|imex:IM-24995-489	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_982287.1|refseq:XP_005247989.1|ensembl:ENSG00000178988(gene)|ensembl:ENST00000320848(transcript)|go:"GO:0042802"(identical protein binding)|interpro:IPR029254|mint:Q96HT8|dip:DIP-29019N|entrezgene/locuslink:114932(identity)	ensemblfungi:YHL004W(gene)|ensemblfungi:YHL004W_mRNA(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR001865(Ribosomal protein S2)|interpro:IPR005706(Ribosomal protein S2, bacterial-type)|interpro:IPR018130|interpro:IPR023591|rcsb pdb:5MRC|rcsb pdb:5MRE|rcsb pdb:5MRF|refseq:NP_011859.1|sgd:S000000996|dip:DIP-5035N|mint:P32902|sgd:YHL004W(identity)	-	caution:This sequence has been withdrawn from Uniprot.|crc64:6C914B0B4BEECAE5	crc64:81A1CB33134BC559	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:hb4enqSS7DeieOByDoLDkXkSlIk9606	rogid:BlL3W6HUN+uAKF/AxwlV1zT5YZQ559292	intact-crc:2B4A216CEFF88922|rigid:BDBlsC/ZZCeS2HYGVz/rgdVL+1Y	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P33297	uniprotkb:P18848	intact:EBI-13920|uniprotkb:D6W2H6|ensemblfungi:YOR117W	intact:EBI-492498|uniprotkb:Q9UH31|ensembl:ENSP00000336790|ensembl:ENSP00000379912|ensembl:ENSP00000501783|ensembl:ENSP00000501863|ensembl:ENSP00000502400|ensembl:ENSP00000502610|ensembl:ENSP00000505360|ensembl:ENSP00000384587|intact:EBI-740263|uniprotkb:Q96AQ3	psi-mi:prs6a_yeast(display_long)|uniprotkb:RPT5(gene name)|psi-mi:RPT5(display_short)|uniprotkb:YTA1(gene name synonym)|uniprotkb:YOR117W(locus name)|uniprotkb:O3258(orf name)|uniprotkb:YOR3258W(orf name)|uniprotkb:Tat-binding protein homolog 1(gene name synonym)	psi-mi:atf4_human(display_long)|uniprotkb:Activating transcription factor 4(gene name synonym)|uniprotkb:CREB2(gene name synonym)|uniprotkb:ATF4(gene name)|psi-mi:ATF4(display_short)|uniprotkb:TXREB(gene name synonym)|uniprotkb:Cyclic AMP-responsive element-binding protein 2(gene name synonym)|uniprotkb:Tax-responsive enhancer element-binding protein 67(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11527071|imex:IM-24995-494	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005643|rcsb pdb:3WHL|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MP9|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|rcsb pdb:3WHK|reactome:R-SCE-5689880|reactome:R-SCE-6798695|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|ensemblfungi:YOR117W(gene)|ensemblfungi:YOR117W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0070682"(proteasome regulatory particle assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035254|interpro:IPR041569|rcsb pdb:3JCO|rcsb pdb:3JCP|refseq:NP_014760.3|mint:P33297|dip:DIP-1590N|sgd:YOR117W(identity)	refseq:NP_001666.2|refseq:NP_877962.1|ensembl:ENSG00000128272(gene)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005886"(plasma membrane)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008140"(cAMP response element binding protein binding)|go:"GO:0010575"(positive regulation of vascular endothelial growth factor production)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030282"(bone mineralization)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0032057"(negative regulation of translational initiation in response to stress)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070309"(lens fiber cell morphogenesis)|go:"GO:0070982"(L-asparagine metabolic process)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0140467"(integrated stress response signaling)|go:"GO:0140468"(HRI-mediated signaling)|go:"GO:1903204"(negative regulation of oxidative stress-induced neuron death)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:1990037"(Lewy body core)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990589"(ATF4-CREB1 transcription factor complex)|go:"GO:1990590"(ATF1-ATF4 transcription factor complex)|go:"GO:1990617"(CHOP-ATF4 complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029811|mint:P18848|rcsb pdb:1CI6|reactome:R-HSA-380994|reactome:R-HSA-381042|reactome:R-HSA-381183|reactome:R-HSA-9633012|reactome:R-HSA-9648895|go:"GO:0043005"(neuron projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045667"(regulation of osteoblast differentiation)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0036003"(positive regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0036091"(positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress)|go:"GO:0036499"(PERK-mediated unfolded protein response)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0061395"(positive regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|ensembl:ENST00000337304(transcript)|ensembl:ENST00000396680(transcript)|ensembl:ENST00000404241(transcript)|ensembl:ENST00000674568(transcript)|ensembl:ENST00000674835(transcript)|ensembl:ENST00000674920(transcript)|ensembl:ENST00000676346(transcript)|ensembl:ENST00000679776(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|refseq:XP_016884296.1|dip:DIP-354N|entrezgene/locuslink:468(identity)	-	crc64:C215422033FCE830	crc64:3BBB7379DC3B0D07|comment:"No Uniprot Update and Caution  removed \" The protein could not be merged with EBI-12907955 because of some conflicts with the protein sequence (features which cannot be shifted).\" -EBI-12907955 no longer exists."	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:jsQE3SjBA0ZZcysuLgFe/5M6pOc559292	rogid:2UolKWXxKFddysaOo70/U/1pI5k9606	intact-crc:232392621DFAB26C|rigid:LpstdSOApZI5A94yRRNDD3wsmz0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32902	uniprotkb:Q9BV19	intact:EBI-16248|ensemblfungi:YHL004W|uniprotkb:D3DKR0	intact:EBI-2874661|ensembl:ENSP00000361603	psi-mi:rt04_yeast(display_long)|uniprotkb:MRP4(gene name)|psi-mi:MRP4(display_short)|uniprotkb:MRP4A(gene name synonym)|uniprotkb:Mitochondrial small ribosomal subunit protein uS2m(gene name synonym)|uniprotkb:YHL004W(locus name)	psi-mi:ca050_human(display_long)|uniprotkb:C1orf50(gene name)|psi-mi:C1orf50(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11527044|imex:IM-24995-491	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YHL004W(gene)|ensemblfungi:YHL004W_mRNA(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR001865(Ribosomal protein S2)|interpro:IPR005706(Ribosomal protein S2, bacterial-type)|interpro:IPR018130|interpro:IPR023591|rcsb pdb:5MRC|rcsb pdb:5MRE|rcsb pdb:5MRF|refseq:NP_011859.1|sgd:S000000996|dip:DIP-5035N|mint:P32902|sgd:YHL004W(identity)	ensembl:ENSG00000164008(gene)|ensembl:ENST00000372525(transcript)|go:"GO:0042802"(identical protein binding)|interpro:IPR019534|refseq:NP_077002.2|entrezgene/locuslink:79078(identity)	-	crc64:81A1CB33134BC559	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:BlL3W6HUN+uAKF/AxwlV1zT5YZQ559292	rogid:TZfvza3lr44CQW5Piu+83qv5Igo9606	intact-crc:651B822C8B8E7160|rigid:TPzZxZtze0xixf9tIGcLTCyl0wE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32902	uniprotkb:Q9H892-2	intact:EBI-16248|ensemblfungi:YHL004W|uniprotkb:D3DKR0	intact:EBI-10274410|ensembl:ENSP00000315160|ensembl:ENSP00000435291	psi-mi:rt04_yeast(display_long)|uniprotkb:MRP4(gene name)|psi-mi:MRP4(display_short)|uniprotkb:MRP4A(gene name synonym)|uniprotkb:Mitochondrial small ribosomal subunit protein uS2m(gene name synonym)|uniprotkb:YHL004W(locus name)	psi-mi:q9h892-2(display_long)|uniprotkb:TTC12(gene name)|psi-mi:TTC12(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11527053|imex:IM-24995-492	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YHL004W(gene)|ensemblfungi:YHL004W_mRNA(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR001865(Ribosomal protein S2)|interpro:IPR005706(Ribosomal protein S2, bacterial-type)|interpro:IPR018130|interpro:IPR023591|rcsb pdb:5MRC|rcsb pdb:5MRE|rcsb pdb:5MRF|refseq:NP_011859.1|sgd:S000000996|dip:DIP-5035N|mint:P32902|sgd:YHL004W(identity)	ensembl:ENSG00000149292(gene)|ensembl:ENST00000314756(transcript)|ensembl:ENST00000494714(transcript)|intact:EBI-2548354(isoform-parent)|uniprotkb:Q9H892-2(isoform-parent)|entrezgene/locuslink:54970(identity)	-	crc64:81A1CB33134BC559	isoform-comment:May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:BlL3W6HUN+uAKF/AxwlV1zT5YZQ559292	rogid:OEjSVGC92wY/pn1l/B1t3wDa3s89606	intact-crc:7DEF0ECE26BB1816|rigid:zk8lMiY4sUBQ9FH8bwjlD/O+26U	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UPY8	uniprotkb:P32902	intact:EBI-726739|uniprotkb:O00265|uniprotkb:Q6FI15|uniprotkb:Q9BZP7|uniprotkb:Q9BZP8|uniprotkb:B7WPK5|uniprotkb:Q6FHB0|ensembl:ENSP00000233121	intact:EBI-16248|ensemblfungi:YHL004W|uniprotkb:D3DKR0	psi-mi:mare3_human(display_long)|uniprotkb:End-binding protein 3(gene name synonym)|uniprotkb:EB1 protein family member 3(gene name synonym)|uniprotkb:RP3(gene name synonym)|uniprotkb:MAPRE3(gene name)|psi-mi:MAPRE3(display_short)	psi-mi:rt04_yeast(display_long)|uniprotkb:MRP4(gene name)|psi-mi:MRP4(display_short)|uniprotkb:MRP4A(gene name synonym)|uniprotkb:Mitochondrial small ribosomal subunit protein uS2m(gene name synonym)|uniprotkb:YHL004W(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11527062|imex:IM-24995-493	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_036458.2|refseq:XP_016859086.1|refseq:NP_001289979.1|refseq:XP_006712030.1|refseq:XP_011531002.1|dip:DIP-56069N|ensembl:ENSG00000084764(gene)|ensembl:ENST00000233121(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0008017"(microtubule binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030496"(midbody)|go:"GO:0031110"(regulation of microtubule polymerization or depolymerization)|go:"GO:0031113"(regulation of microtubule polymerization)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0042802"(identical protein binding)|go:"GO:0045737"(positive regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051233"(spindle midzone)|go:"GO:0051301"(cell division)|go:"GO:1903033"(positive regulation of microtubule plus-end binding)|go:"GO:1904825"(protein localization to microtubule plus-end)|go:"GO:1905721"(mitotic spindle astral microtubule end)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR004953(EB1, C-terminal)|interpro:IPR027328|interpro:IPR027738|interpro:IPR036133|interpro:IPR036872|mint:Q9UPY8|rcsb pdb:1WYO|rcsb pdb:3CO1|rcsb pdb:3JAK|rcsb pdb:3JAL|rcsb pdb:3JAR|rcsb pdb:3TQ7|entrezgene/locuslink:22924(identity)	ensemblfungi:YHL004W(gene)|ensemblfungi:YHL004W_mRNA(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR001865(Ribosomal protein S2)|interpro:IPR005706(Ribosomal protein S2, bacterial-type)|interpro:IPR018130|interpro:IPR023591|rcsb pdb:5MRC|rcsb pdb:5MRE|rcsb pdb:5MRF|refseq:NP_011859.1|sgd:S000000996|dip:DIP-5035N|mint:P32902|sgd:YHL004W(identity)	-	-	crc64:81A1CB33134BC559	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:LHuufxyNrygS3iFW5mmg13R43NE9606	rogid:BlL3W6HUN+uAKF/AxwlV1zT5YZQ559292	intact-crc:0DFD375C83BAD5FD|rigid:y7KhdkY3BxPcBy0QUN8WFq2gJzU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P62333	uniprotkb:P33297	intact:EBI-357669|uniprotkb:Q92524|uniprotkb:P49719|uniprotkb:Q6IBU3|uniprotkb:B2R975|ensembl:ENSP00000401802	intact:EBI-13920|uniprotkb:D6W2H6|ensemblfungi:YOR117W	psi-mi:prs10_human(display_long)|uniprotkb:PSMC6(gene name)|psi-mi:PSMC6(display_short)|uniprotkb:SUG2(gene name synonym)|uniprotkb:Proteasome 26S subunit ATPase 6(gene name synonym)|uniprotkb:Proteasome subunit p42(gene name synonym)|uniprotkb:26S proteasome AAA-ATPase subunit RPT4(gene name synonym)	psi-mi:prs6a_yeast(display_long)|uniprotkb:RPT5(gene name)|psi-mi:RPT5(display_short)|uniprotkb:YTA1(gene name synonym)|uniprotkb:YOR117W(locus name)|uniprotkb:O3258(orf name)|uniprotkb:YOR3258W(orf name)|uniprotkb:Tat-binding protein homolog 1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11527081|imex:IM-24995-495	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002797.3|ensembl:ENST00000445930(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|ensembl:ENSG00000100519(gene)|go:"GO:0005829"(cytosol)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0016234"(inclusion body)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0042802"(identical protein binding)|interpro:IPR032501|interpro:IPR035263|interpro:IPR041569|mint:P62333|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHJ|rcsb pdb:5VHM|rcsb pdb:5VHN|rcsb pdb:5VHO|rcsb pdb:5VHP|rcsb pdb:5VHQ|rcsb pdb:5VHR|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090261"(positive regulation of inclusion body assembly)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-75815|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-174184|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|dip:DIP-38150N|entrezgene/locuslink:5706(identity)	sgd:S000005643|rcsb pdb:3WHL|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MP9|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|rcsb pdb:3WHK|reactome:R-SCE-5689880|reactome:R-SCE-6798695|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|ensemblfungi:YOR117W(gene)|ensemblfungi:YOR117W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0070682"(proteasome regulatory particle assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035254|interpro:IPR041569|rcsb pdb:3JCO|rcsb pdb:3JCP|refseq:NP_014760.3|mint:P33297|dip:DIP-1590N|sgd:YOR117W(identity)	-	-	crc64:C215422033FCE830	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:QE8jzSEp1bpzhOi/oAAnV18QK249606	rogid:jsQE3SjBA0ZZcysuLgFe/5M6pOc559292	intact-crc:8AFD95B4848FDC73|rigid:tsQRSTFYX7nwVpP+XsHPhk23dng	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P33297	uniprotkb:Q9P2K3-2	intact:EBI-13920|uniprotkb:D6W2H6|ensemblfungi:YOR117W	intact:EBI-1504830|ensembl:ENSP00000355973	psi-mi:prs6a_yeast(display_long)|uniprotkb:RPT5(gene name)|psi-mi:RPT5(display_short)|uniprotkb:YTA1(gene name synonym)|uniprotkb:YOR117W(locus name)|uniprotkb:O3258(orf name)|uniprotkb:YOR3258W(orf name)|uniprotkb:Tat-binding protein homolog 1(gene name synonym)	psi-mi:q9p2k3-2(display_long)|uniprotkb:RCOR3(gene name)|psi-mi:RCOR3(display_short)|uniprotkb:KIAA1343(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11527090|imex:IM-24995-496	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005643|rcsb pdb:3WHL|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MP9|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|rcsb pdb:3WHK|reactome:R-SCE-5689880|reactome:R-SCE-6798695|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|ensemblfungi:YOR117W(gene)|ensemblfungi:YOR117W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0070682"(proteasome regulatory particle assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035254|interpro:IPR041569|rcsb pdb:3JCO|rcsb pdb:3JCP|refseq:NP_014760.3|mint:P33297|dip:DIP-1590N|sgd:YOR117W(identity)	ensembl:ENSG00000117625(gene)|ensembl:ENST00000367006(transcript)|intact:EBI-743428(isoform-parent)|uniprotkb:Q9P2K3-2(isoform-parent)|entrezgene/locuslink:55758(identity)	-	crc64:C215422033FCE830	isoform-comment:No experimental confirmation available.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:jsQE3SjBA0ZZcysuLgFe/5M6pOc559292	rogid:RU9KkQB+JnxYVfG5IlAeNKnVFjw9606	intact-crc:72F2DC2920084682|rigid:KGMSSmrer4j3RPiU5j612Dn4HRc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P33417	uniprotkb:B0QYN7	intact:EBI-9401|ensemblfungi:YKL032C|uniprotkb:D6VXQ4	intact:EBI-11525376|ensembl:ENSP00000384361	psi-mi:ixr1_yeast(display_long)|uniprotkb:IXR1(gene name)|psi-mi:IXR1(display_short)|uniprotkb:ORD1(gene name synonym)|uniprotkb:YKL032C(locus name)|uniprotkb:YKL245(orf name)|uniprotkb:Structure-specific recognition protein(gene name synonym)	psi-mi:b0qyn7_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11527128|imex:IM-24995-500	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YKL032C(gene)|ensemblfungi:YKL032C_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0072718"(response to cisplatin)|go:"GO:0090069"(regulation of ribosome biogenesis)|go:"GO:2000819"(regulation of nucleotide-excision repair)|go:"GO:0005634"(nucleus)|reactome:R-SCE-5620971|reactome:R-SCE-5686938|reactome:R-SCE-6798695|sgd:S000001515|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR036910|refseq:NP_012893.3|interpro:IPR033311|reactome:R-SCE-140342|sgd:YKL032C(identity)	refseq:XP_005255597.1|refseq:XP_005255598.1|refseq:XP_011520946.1|refseq:XP_011520947.1|ensembl:ENSG00000103275(gene)|ensembl:ENST00000402301(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0016740"(transferase activity)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|entrezgene/locuslink:7329(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:owYbshNfmIe1+4PkRItBvAQ2GN0559292	rogid:zMqQOA+nnCUquTIxAUwemkElTYI9606	intact-crc:B193503F8CD1B322|rigid:5YXDqeqEV5DFKDVx4WmvJ0fP0ik	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9Y2J4	uniprotkb:P33297	intact:EBI-746752|intact:EBI-28986657|ensembl:ENSP00000409999|uniprotkb:Q53EP1|uniprotkb:Q96F99|uniprotkb:Q9UKB4|uniprotkb:A8K6F1|uniprotkb:B7Z5Q1|uniprotkb:E9PHW3	intact:EBI-13920|uniprotkb:D6W2H6|ensemblfungi:YOR117W	psi-mi:amol2_human(display_long)|uniprotkb:Leman coiled-coil protein(gene name synonym)|uniprotkb:AMOTL2(gene name)|psi-mi:AMOTL2(display_short)|uniprotkb:KIAA0989(gene name synonym)	psi-mi:prs6a_yeast(display_long)|uniprotkb:RPT5(gene name)|psi-mi:RPT5(display_short)|uniprotkb:YTA1(gene name synonym)|uniprotkb:YOR117W(locus name)|uniprotkb:O3258(orf name)|uniprotkb:YOR3258W(orf name)|uniprotkb:Tat-binding protein homolog 1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11527099|imex:IM-24995-497	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001265612.1|refseq:NP_001265614.1|ensembl:ENSG00000114019(gene)|refseq:XP_006713717.1|refseq:NP_057285.3|refseq:XP_011511183.1|ensembl:ENST00000422605(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0003365"(establishment of cell polarity involved in ameboidal cell migration)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0035329"(hippo signaling)|go:"GO:0055037"(recycling endosome)|interpro:IPR009114(Angiomotin)|interpro:IPR024646|mint:Q9Y2J4|reactome:R-HSA-2028269|refseq:XP_016862069.1|refseq:XP_016862070.1|refseq:XP_016862071.1|ensembl:ENST00000249883|ensembl:ENSP00000249883|ensembl:ENSP00000409999|ensembl:ENST00000513145|ensembl:ENSP00000425475|ensembl:ENST00000514516|ensembl:ENSP00000424765|dip:DIP-57510N|entrezgene/locuslink:51421(identity)	sgd:S000005643|rcsb pdb:3WHL|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MP9|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|rcsb pdb:3WHK|reactome:R-SCE-5689880|reactome:R-SCE-6798695|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|ensemblfungi:YOR117W(gene)|ensemblfungi:YOR117W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0070682"(proteasome regulatory particle assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035254|interpro:IPR041569|rcsb pdb:3JCO|rcsb pdb:3JCP|refseq:NP_014760.3|mint:P33297|dip:DIP-1590N|sgd:YOR117W(identity)	-	-	crc64:C215422033FCE830	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:SHtKAcLLnTpSSLwVE7yQ1WECoZk9606	rogid:jsQE3SjBA0ZZcysuLgFe/5M6pOc559292	intact-crc:8587D0CE4834031F|rigid:trg69QZNG/6NNJMYouXfyimxBg0	false	sufficient binding region:314-779	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P33299	uniprotkb:Q16401	intact:EBI-13910|uniprotkb:D6VX51|ensemblfungi:YKL145W	intact:EBI-752143|uniprotkb:Q15045|uniprotkb:Q4VXG8|intact:EBI-10968906|uniprotkb:B4DZM8|ensembl:ENSP00000210313	psi-mi:prs7_yeast(display_long)|uniprotkb:YKL145W(locus name)|uniprotkb:RPT1(gene name)|psi-mi:RPT1(display_short)|uniprotkb:CIM5(gene name synonym)|uniprotkb:YTA3(gene name synonym)|uniprotkb:Protein CIM5(gene name synonym)|uniprotkb:Tat-binding homolog 3(gene name synonym)	psi-mi:psmd5_human(display_long)|uniprotkb:26S proteasome subunit S5B(gene name synonym)|uniprotkb:26S protease subunit S5 basic(gene name synonym)|uniprotkb:PSMD5(gene name)|psi-mi:PSMD5(display_short)|uniprotkb:KIAA0072(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11527110|imex:IM-24995-498	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012777.1|sgd:S000001628|ensemblfungi:YKL145W(gene)|go:"GO:0070682"(proteasome regulatory particle assembly)|interpro:IPR003593(AAA+ ATPase, core)|ensemblfungi:YKL145W_mRNA(transcript)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|go:"GO:0005524"(ATP binding)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR035245|interpro:IPR041569|rcsb pdb:3JCO|rcsb pdb:3JCP|go:"GO:0005634"(nucleus)|rcsb pdb:3VLF|rcsb pdb:4A3V|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:4JPO|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|rcsb pdb:5A5B|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|rcsb pdb:5MP9|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0045732"(positive regulation of protein catabolic process)|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-6798695|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|rcsb pdb:6EF3|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|mint:P33299|dip:DIP-2883N|sgd:YKL145W(identity)	refseq:NP_005038.1|refseq:NP_001257356.1|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|ensembl:ENSG00000095261(gene)|ensembl:ENST00000210313(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0070682"(proteasome regulatory particle assembly)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR019538|mint:Q16401|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|entrezgene/locuslink:5711(identity)	-	crc64:8454BBC9D549EC5C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:8XXo53yZ1KevHObtYWABeFr0hWo559292	rogid:XLVvCeWct98fvc6ktvaWNXwt9dE9606	intact-crc:F2E08D5E2AF2C777|rigid:I7TUR8lYODCxwSY3l1utKDnZ0a8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9H190	uniprotkb:P33322	intact:EBI-742426|ensembl:ENSP00000371233|uniprotkb:O95892|uniprotkb:Q5W0X1|uniprotkb:Q9BZ42|uniprotkb:Q9H567|uniprotkb:Q9NRY8|intact:EBI-28983470|ensembl:ENSP00000342935|ensembl:ENSP00000354013	intact:EBI-4105|ensemblfungi:YLR175W|uniprotkb:D6VYH9	psi-mi:sdcb2_human(display_long)|uniprotkb:Similar to TACIP18(gene name synonym)|uniprotkb:SDCBP2(gene name)|psi-mi:SDCBP2(display_short)|uniprotkb:SITAC18(gene name synonym)|uniprotkb:Syndecan-binding protein 2(gene name synonym)	psi-mi:cbf5_yeast(display_long)|uniprotkb:Small nucleolar RNP protein CBF5(gene name synonym)|uniprotkb:L9470.11(orf name)|uniprotkb:YLR175W(locus name)|uniprotkb:CBF5(gene name)|psi-mi:CBF5(display_short)|uniprotkb:Centromere/microtubule-binding protein CBF5(gene name synonym)|uniprotkb:Centromere-binding factor 5(gene name synonym)|uniprotkb:H/ACA snoRNP protein CBF5(gene name synonym)|uniprotkb:p64'(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11527119|imex:IM-24995-499	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001186713.1|refseq:NP_056500.2|refseq:NP_536737.3|ensembl:ENSP00000342935|ensembl:ENSP00000354013|ensembl:ENST00000381808|ensembl:ENSP00000371229|ensembl:ENSP00000371233|ensembl:ENSG00000125775(gene)|ensembl:ENST00000360779(transcript)|ensembl:ENST00000381812(transcript)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007399"(nervous system development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016607"(nuclear speck)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046907"(intracellular transport)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036034|interpro:IPR041489|ensembl:ENST00000339987(transcript)|entrezgene/locuslink:27111(identity)	ensemblfungi:YLR175W(gene)|ensemblfungi:YLR175W_mRNA(transcript)|go:"GO:0000154"(rRNA modification)|go:"GO:0000495"(box H/ACA RNA 3'-end processing)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0006364"(rRNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0009982"(pseudouridine synthase activity)|go:"GO:0030686"(90S preribosome)|go:"GO:0031118"(rRNA pseudouridine synthesis)|go:"GO:0031120"(snRNA pseudouridine synthesis)|go:"GO:0031429"(box H/ACA snoRNP complex)|go:"GO:0051301"(cell division)|go:"GO:1990481"(mRNA pseudouridine synthesis)|refseq:NP_013276.1|sgd:S000004165|dip:DIP-4472N|mint:P33322|interpro:IPR002478(PUA)|interpro:IPR002501(tRNA pseudouridine synthase B, N-terminal)|interpro:IPR004521(Uncharacterized domain 2)|interpro:IPR004802(Putative rRNA pseudouridine synthase)|interpro:IPR012960(DKCLD)|interpro:IPR015947(PUA-like)|interpro:IPR020103|interpro:IPR032819|interpro:IPR036974|rcsb pdb:3U28|rcsb pdb:3UAI|rcsb pdb:3ZV0|reactome:R-SCE-171319|sgd:YLR175W(identity)	-	-	crc64:D356B39FDCC32E2D	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:vlEtVZkwLTte5PJ4i8ce+SwE/4Y9606	rogid:cBheN/I3bpmiXhl3cWX8OT/YWco559292	intact-crc:9FAA9E923F66F2AC|rigid:4zkyrwd7cHP1mj/wDfoxx/iBTEU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P33417	uniprotkb:P63279	intact:EBI-9401|ensemblfungi:YKL032C|uniprotkb:D6VXQ4	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	psi-mi:ixr1_yeast(display_long)|uniprotkb:IXR1(gene name)|psi-mi:IXR1(display_short)|uniprotkb:ORD1(gene name synonym)|uniprotkb:YKL032C(locus name)|uniprotkb:YKL245(orf name)|uniprotkb:Structure-specific recognition protein(gene name synonym)	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11527138|imex:IM-24995-501	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YKL032C(gene)|ensemblfungi:YKL032C_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0072718"(response to cisplatin)|go:"GO:0090069"(regulation of ribosome biogenesis)|go:"GO:2000819"(regulation of nucleotide-excision repair)|go:"GO:0005634"(nucleus)|reactome:R-SCE-5620971|reactome:R-SCE-5686938|reactome:R-SCE-6798695|sgd:S000001515|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR036910|refseq:NP_012893.3|interpro:IPR033311|reactome:R-SCE-140342|sgd:YKL032C(identity)	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N|entrezgene/locuslink:7329(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:owYbshNfmIe1+4PkRItBvAQ2GN0559292	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	intact-crc:6CE41493E8E015D3|rigid:1+ptW9qqRSPyAxtnJ7cZhUVrGeQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9BW62	uniprotkb:P33441	intact:EBI-743591|uniprotkb:A8K5X4|ensembl:ENSP00000369989|ensembl:ENSP00000369991	intact:EBI-10841|ensemblfungi:YML062C|uniprotkb:D6VZB1	psi-mi:katl1_human(display_long)|uniprotkb:p60 katanin-like 1(gene name synonym)|uniprotkb:KATNAL1(gene name)|psi-mi:KATNAL1(display_short)	psi-mi:mft1_yeast(display_long)|uniprotkb:YML062C(locus name)|uniprotkb:MFT1(gene name)|psi-mi:MFT1(display_short)|uniprotkb:Mitochondrial fusion target protein 1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11527147|imex:IM-24995-502	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001014402.1|refseq:NP_115492.1|refseq:XP_005266631.1|ensembl:ENSG00000102781(gene)|ensembl:ENST00000380615(transcript)|ensembl:ENST00000380617(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005874"(microtubule)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008017"(microtubule binding)|go:"GO:0008568"(microtubule-severing ATPase activity)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016853"(isomerase activity)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0042802"(identical protein binding)|go:"GO:0051013"(microtubule severing)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR027417|interpro:IPR028594|interpro:IPR028596|interpro:IPR041569|rcsb pdb:6B5C|entrezgene/locuslink:84056(identity)	go:"GO:0006397"(mRNA processing)|ensemblfungi:YML062C(gene)|ensemblfungi:YML062C_mRNA(transcript)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0034063"(stress granule assembly)|go:"GO:0060090"(molecular adaptor activity)|interpro:IPR008501(Protein of unknown function DUF783)|go:"GO:0000445"(THO complex part of transcription export complex)|go:"GO:0000446"(nucleoplasmic THO complex)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0006310"(DNA recombination)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|rcsb pdb:7APX|rcsb pdb:7AQO|rcsb pdb:7LUV|refseq:NP_013649.1|sgd:S000004527|mint:P33441|dip:DIP-4537N|sgd:YML062C(identity)	-	-	crc64:45A775F8C1DA3E29	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Usi4KXsvZnNfMOGuWVSz4mfrTaE9606	rogid:QFj+JFK+eAlExAo8oPxdoeJOpNY559292	intact-crc:7849AF88212BDDC7|rigid:vg/BvNAYp1SCVbcB+iAfapVORnk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P35176	uniprotkb:O43765	intact:EBI-5458|uniprotkb:D6VST3|ensemblfungi:YDR304C	intact:EBI-347996|ensembl:ENSP00000221566|ensembl:ENSP00000503397|ensembl:ENSP00000504495|uniprotkb:Q9BTZ9|intact:EBI-1045243|uniprotkb:Q6FIA9|uniprotkb:D6W610	psi-mi:cypd_yeast(display_long)|uniprotkb:CPR5(gene name)|psi-mi:CPR5(display_short)|uniprotkb:YDR304C(locus name)|uniprotkb:D9740.14(orf name)|uniprotkb:CYP5(gene name synonym)|uniprotkb:CYPD(gene name synonym)|uniprotkb:Cyclophilin D(gene name synonym)|uniprotkb:Rotamase D(gene name synonym)	psi-mi:sgta_human(display_long)|uniprotkb:SGTA(gene name)|psi-mi:SGTA(display_short)|uniprotkb:SGT(gene name synonym)|uniprotkb:Alpha-SGT(gene name synonym)|uniprotkb:Vpu-binding protein(gene name synonym)|uniprotkb:SGT1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11527201|imex:IM-24995-508	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002712|refseq:NP_010590.3|dip:DIP-5222N|mint:P35176|ensemblfungi:YDR304C(gene)|ensemblfungi:YDR304C_mRNA(transcript)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006457"(protein folding)|go:"GO:0016018"(cyclosporin A binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|interpro:IPR020892|interpro:IPR029000|sgd:YDR304C(identity)	rcsb pdb:4CPG|rcsb pdb:4GOD|rcsb pdb:4GOE|rcsb pdb:4GOF|reactome:R-HSA-9609523|rcsb pdb:2VYI|ensembl:ENSG00000104969(gene)|ensembl:ENST00000221566(transcript)|ensembl:ENST00000676943(transcript)|ensembl:ENST00000677149(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072380"(TRC complex)|go:"GO:0098850"(extrinsic component of synaptic vesicle membrane)|go:"GO:1903070"(negative regulation of ER-associated ubiquitin-dependent protein catabolic process)|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)|go:"GO:1903646"(positive regulation of chaperone-mediated protein folding)|go:"GO:1904288"(BAT3 complex binding)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR032374|mint:O43765|refseq:XP_011526480.1|refseq:NP_003012.1|entrezgene/locuslink:6449(identity)	-	crc64:F4861424C8443B58	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:aCn3loYoSVWfy5Tb5i+MsOHcUEo559292	rogid:r/Cyj4UJk/cS8QdrbjhTZMPCigI9606	intact-crc:32ED8C486E1FB02C|rigid:qQgJzAnQ9luCe7HRjqJy0vldZ2A	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P35176	uniprotkb:O43681	intact:EBI-5458|uniprotkb:D6VST3|ensemblfungi:YDR304C	intact:EBI-2515857|ensembl:ENSP00000349887|ensembl:ENSP00000466379|uniprotkb:Q53FC6|uniprotkb:A8K740|uniprotkb:A6NHP8|uniprotkb:Q92849|intact:EBI-2818109	psi-mi:cypd_yeast(display_long)|uniprotkb:CPR5(gene name)|psi-mi:CPR5(display_short)|uniprotkb:YDR304C(locus name)|uniprotkb:D9740.14(orf name)|uniprotkb:CYP5(gene name synonym)|uniprotkb:CYPD(gene name synonym)|uniprotkb:Cyclophilin D(gene name synonym)|uniprotkb:Rotamase D(gene name synonym)	psi-mi:get3_human(display_long)|uniprotkb:GET3(gene name)|psi-mi:GET3(display_short)|uniprotkb:ARSA(gene name synonym)|uniprotkb:ASNA1(gene name synonym)|uniprotkb:Arsenical pump-driving ATPase(gene name synonym)|uniprotkb:Arsenite-stimulated ATPase(gene name synonym)|uniprotkb:Guided entry of tail-anchored proteins factor 3, ATPase(gene name synonym)|uniprotkb:TRC40(gene name synonym)|uniprotkb:Transmembrane domain recognition complex 40 kDa ATPase subunit(gene name synonym)|uniprotkb:hARSA-I(gene name synonym)|uniprotkb:hASNA-I(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11527192|imex:IM-24995-507	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002712|refseq:NP_010590.3|dip:DIP-5222N|mint:P35176|ensemblfungi:YDR304C(gene)|ensemblfungi:YDR304C_mRNA(transcript)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006457"(protein folding)|go:"GO:0016018"(cyclosporin A binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|interpro:IPR020892|interpro:IPR029000|sgd:YDR304C(identity)	ensembl:ENSG00000198356(gene)|ensembl:ENST00000357332(transcript)|ensembl:ENST00000591090(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0015105"(arsenite transmembrane transporter activity)|go:"GO:0016787"(hydrolase activity)|go:"GO:0043529"(GET complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|interpro:IPR016300(Arsenite-transporting ATPase)|interpro:IPR025723|interpro:IPR027417|interpro:IPR027542|mint:O43681|rcsb pdb:6SO5|reactome:R-HSA-9609523|refseq:NP_004308.2|entrezgene/locuslink:439(identity)	-	crc64:F4861424C8443B58	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:aCn3loYoSVWfy5Tb5i+MsOHcUEo559292	rogid:j2jKZb3MH8Bd3hnoQhDO6bjbyxI9606	intact-crc:88DD973547258B97|rigid:o1R26f3SK3+5prTF5ubQbsjwHwU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O14641	uniprotkb:P33750	intact:EBI-740850|ensembl:ENSP00000005340|uniprotkb:Q53XM0|uniprotkb:D3DTN3	intact:EBI-17651|uniprotkb:D6VXZ1|ensemblfungi:YLL011W	psi-mi:dvl2_human(display_long)|uniprotkb:DSH homolog 2(gene name synonym)|uniprotkb:DVL2(gene name)|psi-mi:DVL2(display_short)	psi-mi:dca13_yeast(display_long)|uniprotkb:SOF1(gene name)|psi-mi:SOF1(display_short)|uniprotkb:YLL011W(locus name)|uniprotkb:L1339(orf name)|uniprotkb:U3 small nucleolar RNA-associated protein SOF1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11527156|imex:IM-24995-503	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004413.1|ensembl:ENSG00000004975(gene)|ensembl:ENST00000005340(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005109"(frizzled binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0007507"(heart development)|go:"GO:0016235"(aggresome)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044340"(canonical Wnt signaling pathway involved in regulation of cell proliferation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0150012"(positive regulation of neuron projection arborization)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008341(Dishevelled-2 region)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:O14641|rcsb pdb:2REY|rcsb pdb:3CBX|rcsb pdb:3CBY|rcsb pdb:3CBZ|rcsb pdb:3CC0|rcsb pdb:4WIP|rcsb pdb:5LNP|rcsb pdb:5SUY|rcsb pdb:5SUZ|rcsb pdb:6IW3|rcsb pdb:6JCK|reactome:R-HSA-201681|reactome:R-HSA-201688|reactome:R-HSA-2028269|reactome:R-HSA-4086400|reactome:R-HSA-4608870|reactome:R-HSA-4641258|reactome:R-HSA-4641262|reactome:R-HSA-5099900|reactome:R-HSA-5368598|reactome:R-HSA-5663220|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9673324|ensembl:ENSP00000005340|dip:DIP-34433N|entrezgene/locuslink:1856(identity)	ensemblfungi:YLL011W(gene)|ensemblfungi:YLL011W_mRNA(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003729"(mRNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0030686"(90S preribosome)|go:"GO:0032040"(small-subunit processome)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR007287(Sof1-like protein)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR020472|interpro:IPR036322|rcsb pdb:5WLC|rcsb pdb:6KE6|rcsb pdb:6LQP|rcsb pdb:6LQQ|rcsb pdb:6LQR|rcsb pdb:6LQS|rcsb pdb:6LQT|rcsb pdb:6LQU|rcsb pdb:6LQV|rcsb pdb:6ND4|rcsb pdb:6ZQA|rcsb pdb:6ZQB|rcsb pdb:6ZQC|rcsb pdb:6ZQD|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-6791226|refseq:NP_013090.1|sgd:S000003934|dip:DIP-746N|mint:P33750|sgd:YLL011W(identity)	-	-	crc64:4B28371CC61DE7E4	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:2Vdc8oRnT4Mz/j+EXQXrL3AszOc9606	rogid:stTLdABNsa3SvTkNOZBteSNAVJA559292	intact-crc:05EBA6E7D89DE5ED|rigid:j4xjxtpoVQnl/tte5rWikoJ91So	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P34164	uniprotkb:Q99750	intact:EBI-17187|uniprotkb:D6VTU7|ensemblfungi:YGL208W	intact:EBI-724076|ensembl:ENSP00000230321|ensembl:ENSP00000362142	psi-mi:sip2_yeast(display_long)|uniprotkb:SIP2(gene name)|psi-mi:SIP2(display_short)|uniprotkb:SPM2(gene name synonym)|uniprotkb:YGL208W(locus name)|uniprotkb:G1155(orf name)|uniprotkb:Protein SPM2(gene name synonym)|uniprotkb:SNF1-interacting protein 2(gene name synonym)	psi-mi:mdfi_human(display_long)|uniprotkb:Myogenic repressor I-mf(gene name synonym)|uniprotkb:MDFI(gene name)|psi-mi:MDFI(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11527174|imex:IM-24995-505	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011307.1|sgd:S000003176|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0080090"(regulation of primary metabolic process)|go:"GO:2000222"(positive regulation of pseudohyphal growth)|interpro:IPR006828(5-AMP-activated protein kinase, beta subunit, complex-interacting region)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030077|interpro:IPR032640|interpro:IPR037256|rcsb pdb:2QLV|rcsb pdb:3T4N|rcsb pdb:3TDH|rcsb pdb:3TE5|reactome:R-SCE-1632852|reactome:R-SCE-380972|go:"GO:0043254"(regulation of protein-containing complex assembly)|ensemblfungi:YGL208W(gene)|ensemblfungi:YGL208W_mRNA(transcript)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0042149"(cellular response to glucose starvation)|dip:DIP-865N|mint:P34164|sgd:YGL208W(identity)	refseq:NP_005577.1|ensembl:ENSG00000112559(gene)|ensembl:ENST00000230321(transcript)|ensembl:ENST00000373051(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR026134|mint:Q99750|refseq:NP_001287733.1|refseq:NP_001287734.1|refseq:NP_001287735.1|entrezgene/locuslink:4188(identity)	-	crc64:CBB4FCE0070A563F	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:KBJuNhrNAHm6B0INUd1UIiASmok559292	rogid:V3vU0fihMOW18DMHAiDbuZ3asNU9606	intact-crc:5728AD82043488C7|rigid:lVjeUXAAI3amze6bCE5iNeVAqCk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P33750	uniprotkb:Q92997	intact:EBI-17651|uniprotkb:D6VXZ1|ensemblfungi:YLL011W	intact:EBI-739789|uniprotkb:O14642|uniprotkb:Q13531|uniprotkb:Q8N5E9|uniprotkb:Q92607|uniprotkb:D3DNT0|intact:EBI-11081380|uniprotkb:B4E3E5|ensembl:ENSP00000316054	psi-mi:dca13_yeast(display_long)|uniprotkb:SOF1(gene name)|psi-mi:SOF1(display_short)|uniprotkb:YLL011W(locus name)|uniprotkb:L1339(orf name)|uniprotkb:U3 small nucleolar RNA-associated protein SOF1(gene name synonym)	psi-mi:dvl3_human(display_long)|uniprotkb:DVL3(gene name)|psi-mi:DVL3(display_short)|uniprotkb:KIAA0208(gene name synonym)|uniprotkb:DSH homolog 3(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11527165|imex:IM-24995-504	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YLL011W(gene)|ensemblfungi:YLL011W_mRNA(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003729"(mRNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0030686"(90S preribosome)|go:"GO:0032040"(small-subunit processome)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR007287(Sof1-like protein)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR020472|interpro:IPR036322|rcsb pdb:5WLC|rcsb pdb:6KE6|rcsb pdb:6LQP|rcsb pdb:6LQQ|rcsb pdb:6LQR|rcsb pdb:6LQS|rcsb pdb:6LQT|rcsb pdb:6LQU|rcsb pdb:6LQV|rcsb pdb:6ND4|rcsb pdb:6ZQA|rcsb pdb:6ZQB|rcsb pdb:6ZQC|rcsb pdb:6ZQD|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-6791226|refseq:NP_013090.1|sgd:S000003934|dip:DIP-746N|mint:P33750|sgd:YLL011W(identity)	refseq:NP_004414.3|dip:DIP-34509N|ensembl:ENSG00000161202(gene)|ensembl:ENST00000313143(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002020"(protease binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005109"(frizzled binding)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0038031"(non-canonical Wnt signaling pathway via JNK cascade)|go:"GO:0042493"|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050821"(protein stabilization)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0150012"(positive regulation of neuron projection arborization)|go:"GO:1903827"|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008342(Dishevelled-3 protein, C-terminal)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:Q92997|rcsb pdb:6V7O|rcsb pdb:6ZC6|rcsb pdb:6ZC8|reactome:R-HSA-201681|reactome:R-HSA-201688|reactome:R-HSA-4086400|reactome:R-HSA-4641258|reactome:R-HSA-4641262|reactome:R-HSA-5368598|reactome:R-HSA-5663220|reactome:R-HSA-9673324|entrezgene/locuslink:1857(identity)	-	crc64:4B28371CC61DE7E4	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:stTLdABNsa3SvTkNOZBteSNAVJA559292	rogid:yJ3YIp5IhvKTQwa3bK5yTjNyqXk9606	intact-crc:7B3B03C8103B9C8A|rigid:MKlnYeGFXqo+k8PhzoxLEikprNI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9BQ66	uniprotkb:P34164	intact:EBI-739863|uniprotkb:A3KMC5|uniprotkb:Q495I0|ensembl:ENSP00000377582|ensembl:ENSP00000458979	intact:EBI-17187|uniprotkb:D6VTU7|ensemblfungi:YGL208W	psi-mi:kr412_human(display_long)|uniprotkb:KRTAP4-12(gene name)|psi-mi:KRTAP4-12(display_short)|uniprotkb:KAP4.12(gene name synonym)|uniprotkb:KRTAP4.12(gene name synonym)|uniprotkb:Keratin-associated protein 4.12(gene name synonym)|uniprotkb:Ultrahigh sulfur keratin-associated protein 4.12(gene name synonym)	psi-mi:sip2_yeast(display_long)|uniprotkb:SIP2(gene name)|psi-mi:SIP2(display_short)|uniprotkb:SPM2(gene name synonym)|uniprotkb:YGL208W(locus name)|uniprotkb:G1155(orf name)|uniprotkb:Protein SPM2(gene name synonym)|uniprotkb:SNF1-interacting protein 2(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11527183|imex:IM-24995-506	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_114060.1|ensembl:ENSG00000213416(gene)|ensembl:ENSG00000263236(gene)|ensembl:ENST00000394014(transcript)|ensembl:ENST00000571271(transcript)|go:"GO:0045095"(keratin filament)|interpro:IPR002494(Keratin, high sulphur B2 protein)|entrezgene/locuslink:83755(identity)	refseq:NP_011307.1|sgd:S000003176|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0080090"(regulation of primary metabolic process)|go:"GO:2000222"(positive regulation of pseudohyphal growth)|interpro:IPR006828(5-AMP-activated protein kinase, beta subunit, complex-interacting region)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030077|interpro:IPR032640|interpro:IPR037256|rcsb pdb:2QLV|rcsb pdb:3T4N|rcsb pdb:3TDH|rcsb pdb:3TE5|reactome:R-SCE-1632852|reactome:R-SCE-380972|go:"GO:0043254"(regulation of protein-containing complex assembly)|ensemblfungi:YGL208W(gene)|ensemblfungi:YGL208W_mRNA(transcript)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0042149"(cellular response to glucose starvation)|dip:DIP-865N|mint:P34164|sgd:YGL208W(identity)	-	-	crc64:CBB4FCE0070A563F	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:XLiYOwNd549kn287BJWgx5zmDCY9606	rogid:KBJuNhrNAHm6B0INUd1UIiASmok559292	intact-crc:1C0F4F042B6F171D|rigid:hJwboUKLqAXxX4FMOLJNHYPWlWM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P35180	uniprotkb:Q53EZ4	intact:EBI-12522|uniprotkb:D6VUL4|ensemblfungi:YGR082W	intact:EBI-747776|uniprotkb:Q32WF5|uniprotkb:Q3MV20|uniprotkb:Q5VY28|uniprotkb:Q6N034|ensembl:ENSP00000360540|uniprotkb:Q96H32|uniprotkb:Q9NVS7|uniprotkb:B2RDG8|intact:EBI-10173536|uniprotkb:D3DR37|intact:EBI-28973801	psi-mi:tom20_yeast(display_long)|uniprotkb:MOM19(gene name synonym)|uniprotkb:YGR082W(locus name)|uniprotkb:TOM20(gene name)|psi-mi:TOM20(display_short)|uniprotkb:MAS20(gene name synonym)|uniprotkb:Mitochondrial 20 kDa outer membrane protein(gene name synonym)|uniprotkb:Translocase of outer membrane 20 kDa subunit(gene name synonym)|uniprotkb:Protein MAS20(gene name synonym)	psi-mi:cep55_human(display_long)|uniprotkb:Up-regulated in colon cancer 6(gene name synonym)|uniprotkb:CEP55(gene name)|psi-mi:CEP55(display_short)|uniprotkb:URCC6(gene name synonym)|uniprotkb:C10orf3(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11527264|imex:IM-24995-515	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YGR082W(gene)|ensemblfungi:YGR082W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005742"(mitochondrial outer membrane translocase complex)|go:"GO:0016031"(tRNA import into mitochondrion)|go:"GO:0030150"(protein import into mitochondrial matrix)|go:"GO:0030943"(mitochondrion targeting sequence binding)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|interpro:IPR002056(Protein import receptor MAS20)|interpro:IPR023392|refseq:NP_011596.1|sgd:S000003314|dip:DIP-2539N|mint:P35180|sgd:YGR082W(identity)	refseq:NP_001120654.1|refseq:NP_060601.3|ensembl:ENSG00000138180(gene)|ensembl:ENST00000371485(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0014066"(regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0030496"(midbody)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042802"(identical protein binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0061952"(midbody abscission)|go:"GO:0090543"(Flemming body)|go:"GO:1904888"(cranial skeletal system development)|interpro:IPR022008|interpro:IPR038926|mint:Q53EZ4|rcsb pdb:3E1R|rcsb pdb:3WUT|rcsb pdb:3WUU|rcsb pdb:3WUV|go:"GO:0005814"(centriole)|ensembl:ENSP00000360540|dip:DIP-44581N|entrezgene/locuslink:55165(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:7U00YLVWcaegWlJEKzGblv6STx4559292	rogid:tuo36vVb8ZgPDR81YjZFNEg559w9606	intact-crc:0CEABCE8C0C95E2D|rigid:d0peQzDL8PgCsaXwaCi695W2e0Y	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O43765	uniprotkb:P35180	intact:EBI-347996|ensembl:ENSP00000221566|ensembl:ENSP00000503397|ensembl:ENSP00000504495|uniprotkb:Q9BTZ9|intact:EBI-1045243|uniprotkb:Q6FIA9|uniprotkb:D6W610	intact:EBI-12522|uniprotkb:D6VUL4|ensemblfungi:YGR082W	psi-mi:sgta_human(display_long)|uniprotkb:SGTA(gene name)|psi-mi:SGTA(display_short)|uniprotkb:SGT(gene name synonym)|uniprotkb:Alpha-SGT(gene name synonym)|uniprotkb:Vpu-binding protein(gene name synonym)|uniprotkb:SGT1(gene name synonym)	psi-mi:tom20_yeast(display_long)|uniprotkb:MOM19(gene name synonym)|uniprotkb:YGR082W(locus name)|uniprotkb:TOM20(gene name)|psi-mi:TOM20(display_short)|uniprotkb:MAS20(gene name synonym)|uniprotkb:Mitochondrial 20 kDa outer membrane protein(gene name synonym)|uniprotkb:Translocase of outer membrane 20 kDa subunit(gene name synonym)|uniprotkb:Protein MAS20(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11527255|imex:IM-24995-514	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:4CPG|rcsb pdb:4GOD|rcsb pdb:4GOE|rcsb pdb:4GOF|reactome:R-HSA-9609523|rcsb pdb:2VYI|ensembl:ENSG00000104969(gene)|ensembl:ENST00000221566(transcript)|ensembl:ENST00000676943(transcript)|ensembl:ENST00000677149(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072380"(TRC complex)|go:"GO:0098850"(extrinsic component of synaptic vesicle membrane)|go:"GO:1903070"(negative regulation of ER-associated ubiquitin-dependent protein catabolic process)|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)|go:"GO:1903646"(positive regulation of chaperone-mediated protein folding)|go:"GO:1904288"(BAT3 complex binding)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR032374|mint:O43765|refseq:XP_011526480.1|refseq:NP_003012.1|entrezgene/locuslink:6449(identity)	ensemblfungi:YGR082W(gene)|ensemblfungi:YGR082W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005742"(mitochondrial outer membrane translocase complex)|go:"GO:0016031"(tRNA import into mitochondrion)|go:"GO:0030150"(protein import into mitochondrial matrix)|go:"GO:0030943"(mitochondrion targeting sequence binding)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|interpro:IPR002056(Protein import receptor MAS20)|interpro:IPR023392|refseq:NP_011596.1|sgd:S000003314|dip:DIP-2539N|mint:P35180|sgd:YGR082W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:r/Cyj4UJk/cS8QdrbjhTZMPCigI9606	rogid:7U00YLVWcaegWlJEKzGblv6STx4559292	intact-crc:07D196042B3CD6B7|rigid:tCGv0+3PfHGj2CCWFtHvrRZkpUo	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8N6L0	uniprotkb:P35179	intact:EBI-749265|uniprotkb:Q96MC3|ensembl:ENSP00000404220	intact:EBI-16406|ensemblfungi:YDR086C|uniprotkb:D6VS73	psi-mi:kash5_human(display_long)|uniprotkb:KASH5(gene name)|psi-mi:KASH5(display_short)|uniprotkb:CCDC155(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 155(gene name synonym)|uniprotkb:KASH domain-containing protein 5(gene name synonym)	psi-mi:sc61g_yeast(display_long)|uniprotkb:Sec61 complex subunit SSS1(gene name synonym)|uniprotkb:Ssh1 complex subunit SSS1(gene name synonym)|uniprotkb:D4475(orf name)|uniprotkb:YDR086C(locus name)|uniprotkb:SSS1(gene name)|psi-mi:SSS1(display_short)|uniprotkb:Sec61 complex subunit gamma(gene name synonym)|uniprotkb:Ssh1 complex subunit gamma(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11527246|imex:IM-24995-513	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_653289.3|ensembl:ENSG00000161609(gene)|ensembl:ENST00000447857(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034397"(telomere localization)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051225"(spindle assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0090172"(microtubule cytoskeleton organization involved in homologous chromosome segregation)|go:"GO:0090220"(chromosome localization to nuclear envelope involved in homologous chromosome segregation)|go:"GO:0090619"(meiotic spindle pole)|interpro:IPR011992(EF-Hand type)|interpro:IPR028168|interpro:IPR028170|interpro:IPR039508|mint:Q8N6L0|rcsb pdb:6R2I|rcsb pdb:6WMF|entrezgene/locuslink:147872(identity)	ensemblfungi:YDR086C(gene)|ensemblfungi:YDR086C_mRNA(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0015450"(protein-transporting ATPase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0071261"(Ssh1 translocon complex)|interpro:IPR001901(Protein secE/sec61-gamma protein)|interpro:IPR008158(Protein translocase SEC61 complex gamma subunit)|interpro:IPR023391|rcsb pdb:2WW9|rcsb pdb:2WWA|rcsb pdb:6N3Q|rcsb pdb:6ND1|rcsb pdb:7AFT|rcsb pdb:7KAH|rcsb pdb:7KAI|rcsb pdb:7KAJ|rcsb pdb:7KAO|rcsb pdb:7KAP|rcsb pdb:7KAQ|rcsb pdb:7KAR|rcsb pdb:7KAS|rcsb pdb:7KAT|rcsb pdb:7KAU|rcsb pdb:7KB5|reactome:R-SCE-9609523|refseq:NP_010371.1|sgd:S000002493|dip:DIP-2432N|mint:P35179|sgd:YDR086C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Wl9L7AcvDHCZuKjYLn8QgGIbZTc9606	rogid:QIi5kN/8mDxTSvxRiJVi2JsPdws559292	intact-crc:1B3A121964F63DF4|rigid:psdiHjU6yqzLy7znfHlfC8W4pSM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P46379-2	uniprotkb:P35176	intact:EBI-10988864|ensembl:ENSP00000211379|ensembl:ENSP00000365143|ensembl:ENSP00000372938|ensembl:ENSP00000372940|ensembl:ENSP00000389121|ensembl:ENSP00000410156|ensembl:ENSP00000412110|ensembl:ENSP00000413698	intact:EBI-5458|uniprotkb:D6VST3|ensemblfungi:YDR304C	psi-mi:p46379-2(display_long)|uniprotkb:BAG6(gene name)|psi-mi:BAG6(display_short)|uniprotkb:BAG family molecular chaperone regulator 6(gene name synonym)|uniprotkb:BAT3(gene name synonym)|uniprotkb:BCL2-associated athanogene 6(gene name synonym)|uniprotkb:G3(gene name synonym)|uniprotkb:HLA-B-associated transcript 3(gene name synonym)|uniprotkb:Protein G3(gene name synonym)|uniprotkb:Protein Scythe(gene name synonym)	psi-mi:cypd_yeast(display_long)|uniprotkb:CPR5(gene name)|psi-mi:CPR5(display_short)|uniprotkb:YDR304C(locus name)|uniprotkb:D9740.14(orf name)|uniprotkb:CYP5(gene name synonym)|uniprotkb:CYPD(gene name synonym)|uniprotkb:Cyclophilin D(gene name synonym)|uniprotkb:Rotamase D(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11527210|imex:IM-24995-509	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-347552(isoform-parent)|uniprotkb:P46379-2(isoform-parent)|ensembl:ENSG00000096155(gene)|ensembl:ENSG00000204463(gene)|ensembl:ENSG00000229524(gene)|ensembl:ENSG00000233348(gene)|ensembl:ENST00000211379(transcript)|ensembl:ENST00000375976(transcript)|ensembl:ENST00000383446(transcript)|ensembl:ENST00000383448(transcript)|ensembl:ENST00000417144(transcript)|ensembl:ENST00000419847(transcript)|ensembl:ENST00000442479(transcript)|ensembl:ENST00000443182(transcript)|entrezgene/locuslink:7917(identity)	sgd:S000002712|refseq:NP_010590.3|dip:DIP-5222N|mint:P35176|ensemblfungi:YDR304C(gene)|ensemblfungi:YDR304C_mRNA(transcript)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006457"(protein folding)|go:"GO:0016018"(cyclosporin A binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|interpro:IPR020892|interpro:IPR029000|sgd:YDR304C(identity)	-	-	crc64:F4861424C8443B58	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:7y9hxqfcTmnCBRON6qNoHPCdODY9606	rogid:aCn3loYoSVWfy5Tb5i+MsOHcUEo559292	intact-crc:F3B44776A6E000C8|rigid:yPAhK57/pKkWvoSCATzZn63M5Oo	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P35176	uniprotkb:Q9UMX0	intact:EBI-5458|uniprotkb:D6VST3|ensemblfungi:YDR304C	intact:EBI-741480|uniprotkb:Q8IXS9|uniprotkb:Q8N2Q3|uniprotkb:Q9H0T8|uniprotkb:Q9H3R4|uniprotkb:Q9HAZ5|intact:EBI-28967608|ensembl:ENSP00000365576|uniprotkb:Q5T6J5|uniprotkb:Q5T6J9|uniprotkb:A0A024R284	psi-mi:cypd_yeast(display_long)|uniprotkb:CPR5(gene name)|psi-mi:CPR5(display_short)|uniprotkb:YDR304C(locus name)|uniprotkb:D9740.14(orf name)|uniprotkb:CYP5(gene name synonym)|uniprotkb:CYPD(gene name synonym)|uniprotkb:Cyclophilin D(gene name synonym)|uniprotkb:Rotamase D(gene name synonym)	psi-mi:ubql1_human(display_long)|uniprotkb:Protein linking IAP with cytoskeleton 1(gene name synonym)|uniprotkb:UBQLN1(gene name)|psi-mi:UBQLN1(display_short)|uniprotkb:DA41(gene name synonym)|uniprotkb:PLIC1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11527228|imex:IM-24995-511	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002712|refseq:NP_010590.3|dip:DIP-5222N|mint:P35176|ensemblfungi:YDR304C(gene)|ensemblfungi:YDR304C_mRNA(transcript)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006457"(protein folding)|go:"GO:0016018"(cyclosporin A binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|interpro:IPR020892|interpro:IPR029000|sgd:YDR304C(identity)	ensembl:ENST00000257468|ensembl:ENSP00000257468|ensembl:ENSP00000365576|ensembl:ENSG00000135018(gene)|ensembl:ENST00000376395(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000502"(proteasome complex)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016235"(aggresome)|go:"GO:0016236"(macroautophagy)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0019900"(kinase binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035973"(aggrephagy)|go:"GO:0042802"(identical protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0097352"(autophagosome maturation)|go:"GO:1901340"(negative regulation of store-operated calcium channel activity)|go:"GO:1902175"(regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)|interpro:IPR000626(Ubiquitin)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR028430|interpro:IPR029071|mint:Q9UMX0|rcsb pdb:2JY5|rcsb pdb:2JY6|rcsb pdb:2KLC|reactome:R-HSA-8856825|refseq:NP_038466.2|refseq:NP_444295.1|dip:DIP-41629N|entrezgene/locuslink:29979(identity)	-	crc64:F4861424C8443B58	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:aCn3loYoSVWfy5Tb5i+MsOHcUEo559292	rogid:nCFfZbGCTvRYaXhQ4R99XblslvM9606	intact-crc:2ED2CD50BB3DED0F|rigid:YcVJPAT45FfmKo8R3+pr/TEAB2w	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96EQ0	uniprotkb:P35176	intact:EBI-744081|ensembl:ENSP00000370395	intact:EBI-5458|uniprotkb:D6VST3|ensemblfungi:YDR304C	psi-mi:sgtb_human(display_long)|uniprotkb:Beta-SGT(gene name synonym)|uniprotkb:Small glutamine-rich protein with tetratricopeptide repeats 2(gene name synonym)|uniprotkb:SGTB(gene name)|psi-mi:SGTB(display_short)|uniprotkb:SGT2(gene name synonym)	psi-mi:cypd_yeast(display_long)|uniprotkb:CPR5(gene name)|psi-mi:CPR5(display_short)|uniprotkb:YDR304C(locus name)|uniprotkb:D9740.14(orf name)|uniprotkb:CYP5(gene name synonym)|uniprotkb:CYPD(gene name synonym)|uniprotkb:Cyclophilin D(gene name synonym)|uniprotkb:Rotamase D(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11527219|imex:IM-24995-510	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_061945.1|refseq:XP_005248605.1|ensembl:ENSG00000197860(gene)|ensembl:ENST00000381007(transcript)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0072380"(TRC complex)|go:"GO:1903646"(positive regulation of chaperone-mediated protein folding)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR032374|entrezgene/locuslink:54557(identity)	sgd:S000002712|refseq:NP_010590.3|dip:DIP-5222N|mint:P35176|ensemblfungi:YDR304C(gene)|ensemblfungi:YDR304C_mRNA(transcript)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006457"(protein folding)|go:"GO:0016018"(cyclosporin A binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|interpro:IPR020892|interpro:IPR029000|sgd:YDR304C(identity)	-	-	crc64:F4861424C8443B58	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:emIgH8U/yVmXT00Ty9yybIqQqas9606	rogid:aCn3loYoSVWfy5Tb5i+MsOHcUEo559292	intact-crc:3D1247EE50600081|rigid:moBP3cAFyw6oKkz6/z7bg7JEHGU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9Y2W7	uniprotkb:P35176	intact:EBI-751501|uniprotkb:Q53TJ5|uniprotkb:Q96T40|uniprotkb:Q9UJ84|uniprotkb:Q9UJ85|uniprotkb:Q3YAC3|uniprotkb:Q3YAC4|uniprotkb:H7BY46|ensembl:ENSP00000295225	intact:EBI-5458|uniprotkb:D6VST3|ensemblfungi:YDR304C	psi-mi:csen_human(display_long)|uniprotkb:Kv channel-interacting protein 3(gene name synonym)|uniprotkb:A-type potassium channel modulatory protein 3(gene name synonym)|uniprotkb:DRE-antagonist modulator(gene name synonym)|uniprotkb:KCNIP3(gene name)|psi-mi:KCNIP3(display_short)|uniprotkb:DREAM(gene name synonym)|uniprotkb:KCHIP3(gene name synonym)|uniprotkb:CSEN(gene name synonym)	psi-mi:cypd_yeast(display_long)|uniprotkb:CPR5(gene name)|psi-mi:CPR5(display_short)|uniprotkb:YDR304C(locus name)|uniprotkb:D9740.14(orf name)|uniprotkb:CYP5(gene name synonym)|uniprotkb:CYPD(gene name synonym)|uniprotkb:Cyclophilin D(gene name synonym)|uniprotkb:Rotamase D(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11527237|imex:IM-24995-512	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001030086.1|refseq:NP_038462.1|ensembl:ENSG00000115041(gene)|ensembl:ENST00000295225(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005244"(voltage-gated ion channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0030425"(dendrite)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0043679"(axon terminus)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:1901379"(regulation of potassium ion transmembrane transport)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR028846|rcsb pdb:2E6W|reactome:R-HSA-5576894|entrezgene/locuslink:30818(identity)	sgd:S000002712|refseq:NP_010590.3|dip:DIP-5222N|mint:P35176|ensemblfungi:YDR304C(gene)|ensemblfungi:YDR304C_mRNA(transcript)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006457"(protein folding)|go:"GO:0016018"(cyclosporin A binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|interpro:IPR020892|interpro:IPR029000|sgd:YDR304C(identity)	-	-	crc64:F4861424C8443B58	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Mqp4XdEur4uc6jY9dGsn8CHLE4w9606	rogid:aCn3loYoSVWfy5Tb5i+MsOHcUEo559292	intact-crc:3B050B1787517011|rigid:Rgk6L/T/O7f9603f2m87crcxBaE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P35184	uniprotkb:Q53EZ4	intact:EBI-17971|uniprotkb:D6VVU2|ensemblfungi:YIR012W	intact:EBI-747776|uniprotkb:Q32WF5|uniprotkb:Q3MV20|uniprotkb:Q5VY28|uniprotkb:Q6N034|ensembl:ENSP00000360540|uniprotkb:Q96H32|uniprotkb:Q9NVS7|uniprotkb:B2RDG8|intact:EBI-10173536|uniprotkb:D3DR37|intact:EBI-28973801	psi-mi:sqt1_yeast(display_long)|uniprotkb:YIB12W(orf name)|uniprotkb:YIR012W(locus name)|uniprotkb:SQT1(gene name)|psi-mi:SQT1(display_short)	psi-mi:cep55_human(display_long)|uniprotkb:Up-regulated in colon cancer 6(gene name synonym)|uniprotkb:CEP55(gene name)|psi-mi:CEP55(display_short)|uniprotkb:URCC6(gene name synonym)|uniprotkb:C10orf3(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11527338|imex:IM-24995-523	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012277.1|sgd:S000001451|ensemblfungi:YIR012W_mRNA(transcript)|ensemblfungi:YIR012W(gene)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|rcsb pdb:4ZOV|rcsb pdb:4ZOX|rcsb pdb:5AMS|dip:DIP-2508N|mint:P35184|sgd:YIR012W(identity)	refseq:NP_001120654.1|refseq:NP_060601.3|ensembl:ENSG00000138180(gene)|ensembl:ENST00000371485(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0014066"(regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0030496"(midbody)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042802"(identical protein binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0061952"(midbody abscission)|go:"GO:0090543"(Flemming body)|go:"GO:1904888"(cranial skeletal system development)|interpro:IPR022008|interpro:IPR038926|mint:Q53EZ4|rcsb pdb:3E1R|rcsb pdb:3WUT|rcsb pdb:3WUU|rcsb pdb:3WUV|go:"GO:0005814"(centriole)|ensembl:ENSP00000360540|dip:DIP-44581N|entrezgene/locuslink:55165(identity)	-	crc64:981D566076B0C881	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:u/Q5uAjR85ZD3op0nHiN20IVCLY559292	rogid:tuo36vVb8ZgPDR81YjZFNEg559w9606	intact-crc:FEAEEE1FD2EDD704|rigid:kLNE7nwqG2v/iClYBogzIR2poAo	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12800	uniprotkb:P35184	intact:EBI-717422|uniprotkb:Q12801|uniprotkb:Q9UD77|uniprotkb:A8K5E9|uniprotkb:Q9UD75|ensembl:ENSP00000257915	intact:EBI-17971|uniprotkb:D6VVU2|ensemblfungi:YIR012W	psi-mi:tfcp2_human(display_long)|uniprotkb:Transcription factor LSF(gene name synonym)|uniprotkb:SAA3 enhancer factor(gene name synonym)|uniprotkb:TFCP2(gene name)|psi-mi:TFCP2(display_short)|uniprotkb:LSF(gene name synonym)|uniprotkb:SEF(gene name synonym)	psi-mi:sqt1_yeast(display_long)|uniprotkb:YIB12W(orf name)|uniprotkb:YIR012W(locus name)|uniprotkb:SQT1(gene name)|psi-mi:SQT1(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11527329|imex:IM-24995-522	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001166923.1|refseq:NP_001166924.1|refseq:NP_005644.2|ensembl:ENSG00000135457(gene)|ensembl:ENST00000257915(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR007604(CP2 transcription factor)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR037599|interpro:IPR041418|mint:Q12800|entrezgene/locuslink:7024(identity)	refseq:NP_012277.1|sgd:S000001451|ensemblfungi:YIR012W_mRNA(transcript)|ensemblfungi:YIR012W(gene)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|rcsb pdb:4ZOV|rcsb pdb:4ZOX|rcsb pdb:5AMS|dip:DIP-2508N|mint:P35184|sgd:YIR012W(identity)	-	-	crc64:981D566076B0C881	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:M7mQ08NDYxuawmUEKRgjSdIr+Og9606	rogid:u/Q5uAjR85ZD3op0nHiN20IVCLY559292	intact-crc:8F5A46B934343C99|rigid:FMPTmQoz52SdPqULmpj3dGDYuNo	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P35184	uniprotkb:P14373	intact:EBI-17971|uniprotkb:D6VVU2|ensemblfungi:YIR012W	intact:EBI-719493|uniprotkb:A2BE15|uniprotkb:Q5RJA8|uniprotkb:Q5ST26|uniprotkb:Q6LA73|uniprotkb:Q6NXR9|uniprotkb:Q9BZY6|uniprotkb:Q9UJL3|ensembl:ENSP00000383555|ensembl:ENSP00000392787|ensembl:ENSP00000405229|ensembl:ENSP00000414793|ensembl:ENSP00000366404	psi-mi:sqt1_yeast(display_long)|uniprotkb:YIB12W(orf name)|uniprotkb:YIR012W(locus name)|uniprotkb:SQT1(gene name)|psi-mi:SQT1(display_short)	psi-mi:tri27_human(display_long)|uniprotkb:TRIM27(gene name)|psi-mi:TRIM27(display_short)|uniprotkb:RNF76(gene name synonym)|uniprotkb:RFP(gene name synonym)|uniprotkb:Ret finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 27(gene name synonym)|uniprotkb:RING finger protein 76(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM27(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11527320|imex:IM-24995-521	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012277.1|sgd:S000001451|ensemblfungi:YIR012W_mRNA(transcript)|ensemblfungi:YIR012W(gene)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|rcsb pdb:4ZOV|rcsb pdb:4ZOX|rcsb pdb:5AMS|dip:DIP-2508N|mint:P35184|sgd:YIR012W(identity)	refseq:NP_006501.1|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0090281"(negative regulation of calcium ion import)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR020457|interpro:IPR035791|interpro:IPR043136|mint:P14373|reactome:R-HSA-3232142|reactome:R-HSA-9635465|reactome:R-HSA-8948751|ensembl:ENSG00000204713(gene)|ensembl:ENSG00000215641(gene)|ensembl:ENSG00000229006(gene)|ensembl:ENSG00000234495(gene)|ensembl:ENSG00000237071(gene)|ensembl:ENST00000377199(transcript)|ensembl:ENST00000400720(transcript)|ensembl:ENST00000431123(transcript)|ensembl:ENST00000435528(transcript)|ensembl:ENST00000437160(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001650"(fibrillar center)|go:"GO:0002820"(negative regulation of adaptive immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|entrezgene/locuslink:5987(identity)	-	crc64:981D566076B0C881	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:u/Q5uAjR85ZD3op0nHiN20IVCLY559292	rogid:dsfH5OUghD8KSaTz1SFw9OYVTK49606	intact-crc:2018D71EB7A47069|rigid:yNAYNi8fy6ovb44xWu73iHfwTu8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P35180	uniprotkb:Q8N6Y0	intact:EBI-12522|uniprotkb:D6VUL4|ensemblfungi:YGR082W	intact:EBI-739895|uniprotkb:Q8NBX7|uniprotkb:Q96KH3|uniprotkb:Q9BYI8|uniprotkb:A8K7L6|uniprotkb:B2RCR9|ensembl:ENSP00000252597	psi-mi:tom20_yeast(display_long)|uniprotkb:MOM19(gene name synonym)|uniprotkb:YGR082W(locus name)|uniprotkb:TOM20(gene name)|psi-mi:TOM20(display_short)|uniprotkb:MAS20(gene name synonym)|uniprotkb:Mitochondrial 20 kDa outer membrane protein(gene name synonym)|uniprotkb:Translocase of outer membrane 20 kDa subunit(gene name synonym)|uniprotkb:Protein MAS20(gene name synonym)	psi-mi:usbp1_human(display_long)|uniprotkb:USHBP1(gene name)|psi-mi:USHBP1(display_short)|uniprotkb:MCC-2(gene name synonym)|uniprotkb:AIE-75-binding protein(gene name synonym)|uniprotkb:AIEBP(gene name synonym)|uniprotkb:MCC2(gene name synonym)|uniprotkb:Mutated in colon cancer protein 2(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11527273|imex:IM-24995-516	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YGR082W(gene)|ensemblfungi:YGR082W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005742"(mitochondrial outer membrane translocase complex)|go:"GO:0016031"(tRNA import into mitochondrion)|go:"GO:0030150"(protein import into mitochondrial matrix)|go:"GO:0030943"(mitochondrion targeting sequence binding)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|interpro:IPR002056(Protein import receptor MAS20)|interpro:IPR023392|refseq:NP_011596.1|sgd:S000003314|dip:DIP-2539N|mint:P35180|sgd:YGR082W(identity)	refseq:NP_001284632.1|refseq:NP_114147.2|refseq:NP_001308346.1|ensembl:ENSG00000130307(gene)|ensembl:ENST00000252597(transcript)|go:"GO:0030165"(PDZ domain binding)|interpro:IPR019536|interpro:IPR040171|entrezgene/locuslink:83878(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:7U00YLVWcaegWlJEKzGblv6STx4559292	rogid:vY1qx73Ju/z7WDu6k1kd10ZDVRo9606	intact-crc:EFC62A553547E59F|rigid:vYGsXdseBt/8LAaKlng/wBgT/jY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8WV92	uniprotkb:P35182	intact:EBI-2691489|uniprotkb:Q69YV0|ensembl:ENSP00000289359	intact:EBI-12784|uniprotkb:D6VRY2|ensemblfungi:YDL006W	psi-mi:mitd1_human(display_long)|uniprotkb:MITD1(gene name)|psi-mi:MITD1(display_short)	psi-mi:pp2c1_yeast(display_long)|uniprotkb:PTC1(gene name)|psi-mi:PTC1(display_short)|uniprotkb:TPD1(gene name synonym)|uniprotkb:YDL006W(locus name)|uniprotkb:D2925(orf name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11527300|imex:IM-24995-519	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_620153.1|refseq:NP_001307346.1|refseq:NP_001307347.1|refseq:NP_001307348.1|ensembl:ENSG00000158411(gene)|ensembl:ENST00000289359(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030496"(midbody)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0061952"(midbody abscission)|go:"GO:0070062"(extracellular exosome)|interpro:IPR007330(MIT)|interpro:IPR032341|interpro:IPR036181|interpro:IPR038113|rcsb pdb:2YMB|rcsb pdb:4A5X|rcsb pdb:4A5Z|entrezgene/locuslink:129531(identity)	interpro:IPR000222(Protein phosphatase 2C,  manganese/magnesium aspartate binding site)|interpro:IPR001932(Protein phosphatase 2C-related)|interpro:IPR015655(Protein phosphatase 2C)|interpro:IPR036457|ensemblfungi:YDL006W(gene)|ensemblfungi:YDL006W_mRNA(transcript)|go:"GO:0000001"(mitochondrion inheritance)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006388"(tRNA splicing, via endonucleolytic cleavage and ligation)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0046872"(metal ion binding)|go:"GO:0051389"(obsolete inactivation of MAPKK activity)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1990439"(MAP kinase serine/threonine phosphatase activity)|refseq:NP_010278.3|sgd:S000002164|mint:P35182|dip:DIP-1537N|sgd:YDL006W(identity)	-	-	crc64:FA384D2541B20D50	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:VY5MeLAmoWXB0gKSJR3d9OhT1Vk9606	rogid:iWNdaik/M9S814zgZEQNyOktcX8559292	intact-crc:CB992B885BB132D0|rigid:knJUSs7YD4HeXZ2EhLi6hDFYgDI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P35180	uniprotkb:Q9UHV2	intact:EBI-12522|uniprotkb:D6VUL4|ensemblfungi:YGR082W	intact:EBI-748601|uniprotkb:Q9BUE7|ensembl:ENSP00000350633	psi-mi:tom20_yeast(display_long)|uniprotkb:MOM19(gene name synonym)|uniprotkb:YGR082W(locus name)|uniprotkb:TOM20(gene name)|psi-mi:TOM20(display_short)|uniprotkb:MAS20(gene name synonym)|uniprotkb:Mitochondrial 20 kDa outer membrane protein(gene name synonym)|uniprotkb:Translocase of outer membrane 20 kDa subunit(gene name synonym)|uniprotkb:Protein MAS20(gene name synonym)	psi-mi:srtd1_human(display_long)|uniprotkb:Transcriptional regulator interacting with the PHD-bromodomain 1(gene name synonym)|uniprotkb:CDK4-binding protein p34SEI1(gene name synonym)|uniprotkb:SERTAD1(gene name)|psi-mi:SERTAD1(display_short)|uniprotkb:SEI1(gene name synonym)|uniprotkb:TRIPBR1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11527291|imex:IM-24995-518	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YGR082W(gene)|ensemblfungi:YGR082W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005742"(mitochondrial outer membrane translocase complex)|go:"GO:0016031"(tRNA import into mitochondrion)|go:"GO:0030150"(protein import into mitochondrial matrix)|go:"GO:0030943"(mitochondrion targeting sequence binding)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|interpro:IPR002056(Protein import receptor MAS20)|interpro:IPR023392|refseq:NP_011596.1|sgd:S000003314|dip:DIP-2539N|mint:P35180|sgd:YGR082W(identity)	refseq:NP_037508.2|ensembl:ENSG00000197019(gene)|ensembl:ENST00000357949(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048096"|interpro:IPR009263(SERTA)|mint:Q9UHV2|entrezgene/locuslink:29950(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:7U00YLVWcaegWlJEKzGblv6STx4559292	rogid:40dvjniwxY/UQiyoVREicctpWe09606	intact-crc:65B7DC0961DABC14|rigid:gFB1jmG7TnN9Eb/EoV3Dfz5AHN0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P35180	uniprotkb:Q8NHQ1	intact:EBI-12522|uniprotkb:D6VUL4|ensemblfungi:YGR082W	intact:EBI-739624|ensembl:ENSP00000264982|ensembl:ENSP00000419231|uniprotkb:Q96B31|uniprotkb:Q9H2C3|uniprotkb:Q9H2Z1|uniprotkb:Q9H940|uniprotkb:D3DNE9|uniprotkb:B7Z5I8|uniprotkb:B7Z7E8|uniprotkb:F5GZX8	psi-mi:tom20_yeast(display_long)|uniprotkb:MOM19(gene name synonym)|uniprotkb:YGR082W(locus name)|uniprotkb:TOM20(gene name)|psi-mi:TOM20(display_short)|uniprotkb:MAS20(gene name synonym)|uniprotkb:Mitochondrial 20 kDa outer membrane protein(gene name synonym)|uniprotkb:Translocase of outer membrane 20 kDa subunit(gene name synonym)|uniprotkb:Protein MAS20(gene name synonym)	psi-mi:cep70_human(display_long)|uniprotkb:CEP70(gene name)|psi-mi:CEP70(display_short)|uniprotkb:BITE(gene name synonym)|uniprotkb:p10-binding protein(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11527282|imex:IM-24995-517	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YGR082W(gene)|ensemblfungi:YGR082W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005742"(mitochondrial outer membrane translocase complex)|go:"GO:0016031"(tRNA import into mitochondrion)|go:"GO:0030150"(protein import into mitochondrial matrix)|go:"GO:0030943"(mitochondrion targeting sequence binding)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|interpro:IPR002056(Protein import receptor MAS20)|interpro:IPR023392|refseq:NP_011596.1|sgd:S000003314|dip:DIP-2539N|mint:P35180|sgd:YGR082W(identity)	ensembl:ENSG00000114107(gene)|ensembl:ENST00000264982(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|interpro:IPR019734|interpro:IPR037692|mint:Q8NHQ1|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|ensembl:ENST00000484888(transcript)|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_077817.2|refseq:XP_016862764.1|refseq:NP_001275893.1|refseq:NP_001275894.1|refseq:NP_001275895.1|refseq:NP_001275896.1|refseq:NP_001307527.1|refseq:NP_001307529.1|entrezgene/locuslink:80321(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:7U00YLVWcaegWlJEKzGblv6STx4559292	rogid:S4yveQWcvdVtAUX65gqrJ5Dv0Mc9606	intact-crc:2E7F7BA7F6D9276F|rigid:z7WBjT6L0UwP5vPIEbn0OubQKjM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P35184	uniprotkb:Q08379	intact:EBI-17971|uniprotkb:D6VVU2|ensemblfungi:YIR012W	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	psi-mi:sqt1_yeast(display_long)|uniprotkb:YIB12W(orf name)|uniprotkb:YIR012W(locus name)|uniprotkb:SQT1(gene name)|psi-mi:SQT1(display_short)	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11527309|imex:IM-24995-520	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012277.1|sgd:S000001451|ensemblfungi:YIR012W_mRNA(transcript)|ensemblfungi:YIR012W(gene)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|rcsb pdb:4ZOV|rcsb pdb:4ZOX|rcsb pdb:5AMS|dip:DIP-2508N|mint:P35184|sgd:YIR012W(identity)	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N|entrezgene/locuslink:2801(identity)	-	crc64:981D566076B0C881	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2017/05/26	rogid:u/Q5uAjR85ZD3op0nHiN20IVCLY559292	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	intact-crc:BC0A9AFD5AAEA83C|rigid:4cdxPE30cCZSDpIJI9J3f+4xJLw	false	-	sufficient binding region:383-1002	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9NSC5	uniprotkb:P35191	intact:EBI-748420|uniprotkb:O14580|uniprotkb:O95350|uniprotkb:Q9NSB9|uniprotkb:Q9NSC0|intact:EBI-2557809|uniprotkb:E9PCW9|uniprotkb:Q9NSC1|intact:EBI-28972925|ensembl:ENSP00000376162|ensembl:ENSP00000439937|ensembl:ENSP00000446026|intact:EBI-10175777|uniprotkb:B2RA10	intact:EBI-10603|ensemblfungi:YFL016C|uniprotkb:D6VTL4	psi-mi:home3_human(display_long)|uniprotkb:HOMER3(gene name)|psi-mi:HOMER3(display_short)	psi-mi:mdj1_yeast(display_long)|uniprotkb:YFL016C(locus name)|uniprotkb:MDJ1(gene name)|psi-mi:MDJ1(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11527420|imex:IM-24995-531	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000221222|ensembl:ENSP00000221222|ensembl:ENSP00000376162|ensembl:ENST00000433218|ensembl:ENSP00000396154|ensembl:ENSP00000439937|ensembl:ENSP00000446026|ensembl:ENST00000594439|ensembl:ENSP00000471835|refseq:XP_006723006.1|refseq:XP_006723007.1|refseq:NP_001139193.1|refseq:NP_001139194.1|refseq:NP_004829.3|refseq:NP_001139196.1|ensembl:ENSG00000051128(gene)|ensembl:ENST00000392351(transcript)|ensembl:ENST00000539827(transcript)|ensembl:ENST00000542541(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006605"(protein targeting)|go:"GO:0007216"(G protein-coupled glutamate receptor signaling pathway)|go:"GO:0014069"(postsynaptic density)|go:"GO:0030425"(dendrite)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0035256"(G protein-coupled glutamate receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|go:"GO:2001256"(regulation of store-operated calcium entry)|interpro:IPR000697(EVH1)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR044100|mint:Q9NSC5|rcsb pdb:2P8V|rcsb pdb:3CVF|reactome:R-HSA-6794361|entrezgene/locuslink:9454(identity)	ensemblfungi:YFL016C(gene)|ensemblfungi:YFL016C_mRNA(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0009408"(response to heat)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031314"(extrinsic component of mitochondrial inner membrane)|go:"GO:0042026"(protein refolding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|interpro:IPR001305(Heat shock protein DnaJ, cysteine-rich region)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR012724(Chaperone DnaJ)|interpro:IPR018253|interpro:IPR036410|interpro:IPR036869|go:"GO:0005759"(mitochondrial matrix)|refseq:NP_116638.1|sgd:S000001878|mint:P35191|dip:DIP-764N|sgd:YFL016C(identity)	-	-	crc64:007343427C66D2B6	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:U1y/y52nnf7zQUCNQlqk7JDgXi49606	rogid:2JbQztkUZ2kj7Y45Ghq1vTAhYdU559292	intact-crc:FF6162F68C41C674|rigid:bMATE5CfS2vO46/cf0YpYoWM7VY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P35184	uniprotkb:Q9UJV3-2	intact:EBI-17971|uniprotkb:D6VVU2|ensemblfungi:YIR012W	intact:EBI-10172526|ensembl:ENSP00000413976	psi-mi:sqt1_yeast(display_long)|uniprotkb:YIB12W(orf name)|uniprotkb:YIR012W(locus name)|uniprotkb:SQT1(gene name)|psi-mi:SQT1(display_short)	psi-mi:q9ujv3-2(display_long)|uniprotkb:RING-type E3 ubiquitin transferase MID2(gene name synonym)|uniprotkb:FXY2(gene name synonym)|uniprotkb:Midin-2(gene name synonym)|uniprotkb:Midline defect 2(gene name synonym)|uniprotkb:Midline-2(gene name synonym)|uniprotkb:RING finger protein 60(gene name synonym)|uniprotkb:RNF60(gene name synonym)|uniprotkb:TRIM1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 1(gene name synonym)|uniprotkb:MID2(gene name)|psi-mi:MID2(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11527409|imex:IM-24995-530	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012277.1|sgd:S000001451|ensemblfungi:YIR012W_mRNA(transcript)|ensemblfungi:YIR012W(gene)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|rcsb pdb:4ZOV|rcsb pdb:4ZOX|rcsb pdb:5AMS|dip:DIP-2508N|mint:P35184|sgd:YIR012W(identity)	intact:EBI-751983(isoform-parent)|uniprotkb:Q9UJV3-2(isoform-parent)|ensembl:ENSG00000080561(gene)|ensembl:ENST00000443968(transcript)|entrezgene/locuslink:11043(identity)	-	crc64:981D566076B0C881	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:u/Q5uAjR85ZD3op0nHiN20IVCLY559292	rogid:/FJ+V2H7SaWon7caUWkEkmHFVxQ9606	intact-crc:358127B0C4F7BC71|rigid:SKAxlSi558MbzGjE3wZvuhoaL34	false	-	sufficient binding region:21-705	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P35184	uniprotkb:Q9NVV9	intact:EBI-17971|uniprotkb:D6VVU2|ensemblfungi:YIR012W	intact:EBI-741515|uniprotkb:Q53FQ1|uniprotkb:Q6IA99|ensembl:ENSP00000254250|uniprotkb:A6NCB6|uniprotkb:D3DSY5|uniprotkb:H9KV49	psi-mi:sqt1_yeast(display_long)|uniprotkb:YIB12W(orf name)|uniprotkb:YIR012W(locus name)|uniprotkb:SQT1(gene name)|psi-mi:SQT1(display_short)	psi-mi:thap1_human(display_long)|uniprotkb:THAP1(gene name)|psi-mi:THAP1(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11527400|imex:IM-24995-529	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012277.1|sgd:S000001451|ensemblfungi:YIR012W_mRNA(transcript)|ensemblfungi:YIR012W(gene)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|rcsb pdb:4ZOV|rcsb pdb:4ZOX|rcsb pdb:5AMS|dip:DIP-2508N|mint:P35184|sgd:YIR012W(identity)	refseq:NP_060575.1|ensembl:ENSG00000131931(gene)|ensembl:ENST00000254250(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001650"(fibrillar center)|go:"GO:0001935"(endothelial cell proliferation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007049"(cell cycle)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016605"(PML body)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR006612(Zinc finger, C2CH-type)|interpro:IPR026516|interpro:IPR038441|mint:Q9NVV9|rcsb pdb:2JTG|rcsb pdb:2KO0|rcsb pdb:2L1G|refseq:NP_945354.1|entrezgene/locuslink:55145(identity)	-	crc64:981D566076B0C881	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:u/Q5uAjR85ZD3op0nHiN20IVCLY559292	rogid:/KO90pu5tBnIVq9SMx1JYPXFCEQ9606	intact-crc:F3120783CB86FE60|rigid:MYQZw2Ov9iO6TKFJqd/zpvZgQTc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P35184	uniprotkb:Q8IXK0-5	intact:EBI-17971|uniprotkb:D6VVU2|ensemblfungi:YIR012W	intact:EBI-11527347|ensembl:ENSP00000507877	psi-mi:sqt1_yeast(display_long)|uniprotkb:YIB12W(orf name)|uniprotkb:YIR012W(locus name)|uniprotkb:SQT1(gene name)|psi-mi:SQT1(display_short)	psi-mi:q8ixk0-5(display_long)|uniprotkb:EDR2(gene name synonym)|uniprotkb:Early development regulatory protein 2(gene name synonym)|uniprotkb:PH2(gene name synonym)|uniprotkb:PHC2(gene name)|psi-mi:PHC2(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11527351|imex:IM-24995-524	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012277.1|sgd:S000001451|ensemblfungi:YIR012W_mRNA(transcript)|ensemblfungi:YIR012W(gene)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|rcsb pdb:4ZOV|rcsb pdb:4ZOX|rcsb pdb:5AMS|dip:DIP-2508N|mint:P35184|sgd:YIR012W(identity)	ensembl:ENSG00000134686(gene)|ensembl:ENST00000683057(transcript)|intact:EBI-713786(isoform-parent)|uniprotkb:Q8IXK0-5(isoform-parent)|entrezgene/locuslink:1912(identity)	-	crc64:981D566076B0C881	isoform-comment:No experimental confirmation available.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:u/Q5uAjR85ZD3op0nHiN20IVCLY559292	rogid:bkZ10pedX8mCMrcppjyd4tl7hm09606	intact-crc:77AC1C9E8CECF96C|rigid:Wn06aGS6Uorm+NPpnOaPqfFHt+U	false	-	sufficient binding region:537-859	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q93062-3	uniprotkb:P35184	intact:EBI-740343|ensembl:ENSP00000340176	intact:EBI-17971|uniprotkb:D6VVU2|ensemblfungi:YIR012W	psi-mi:q93062-3(display_long)|uniprotkb:RBPMS(gene name)|psi-mi:RBPMS(display_short)|uniprotkb:HERMES(gene name synonym)|uniprotkb:Heart and RRM expressed sequence(gene name synonym)	psi-mi:sqt1_yeast(display_long)|uniprotkb:YIB12W(orf name)|uniprotkb:YIR012W(locus name)|uniprotkb:SQT1(gene name)|psi-mi:SQT1(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11527382|imex:IM-24995-527	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-740322(rbpms_human)|uniprotkb:Q93062-3(isoform-parent)|ensembl:ENSG00000157110(gene)|ensembl:ENST00000339877(transcript)|entrezgene/locuslink:11030(identity)	refseq:NP_012277.1|sgd:S000001451|ensemblfungi:YIR012W_mRNA(transcript)|ensemblfungi:YIR012W(gene)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|rcsb pdb:4ZOV|rcsb pdb:4ZOX|rcsb pdb:5AMS|dip:DIP-2508N|mint:P35184|sgd:YIR012W(identity)	-	-	crc64:981D566076B0C881	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:nlPMQAJoKEbPYBwsL3xodmCKd7c9606	rogid:u/Q5uAjR85ZD3op0nHiN20IVCLY559292	intact-crc:CF75CA8C94CC9E9D|rigid:RFJo/2SQSQpoKxOsKkKuJxcY/ow	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P35184	uniprotkb:Q8N9N5-2	intact:EBI-17971|uniprotkb:D6VVU2|ensemblfungi:YIR012W	intact:EBI-11524452|ensembl:ENSP00000347125	psi-mi:sqt1_yeast(display_long)|uniprotkb:YIB12W(orf name)|uniprotkb:YIR012W(locus name)|uniprotkb:SQT1(gene name)|psi-mi:SQT1(display_short)	psi-mi:q8n9n5-2(display_long)|uniprotkb:BANP(gene name)|psi-mi:BANP(display_short)|uniprotkb:BEN domain-containing protein 1(gene name synonym)|uniprotkb:BEND1(gene name synonym)|uniprotkb:Btg3-associated nuclear protein(gene name synonym)|uniprotkb:SMAR1(gene name synonym)|uniprotkb:Scaffold/matrix-associated region-1-binding protein(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11527373|imex:IM-24995-526	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012277.1|sgd:S000001451|ensemblfungi:YIR012W_mRNA(transcript)|ensemblfungi:YIR012W(gene)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|rcsb pdb:4ZOV|rcsb pdb:4ZOX|rcsb pdb:5AMS|dip:DIP-2508N|mint:P35184|sgd:YIR012W(identity)	ensembl:ENSG00000172530(gene)|ensembl:ENST00000355022(transcript)|intact:EBI-744695(isoform-parent)|uniprotkb:Q8N9N5-2(isoform-parent)|entrezgene/locuslink:54971(identity)	-	crc64:981D566076B0C881	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:u/Q5uAjR85ZD3op0nHiN20IVCLY559292	rogid:ESe6iCAhvq+i57fQHz3rGyg6UOo9606	intact-crc:A79784706532E572|rigid:kNLcFGB1nOnQGr7O4/Jatl49fLg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P35184	uniprotkb:Q8N7W2-2	intact:EBI-17971|uniprotkb:D6VVU2|ensemblfungi:YIR012W	intact:EBI-10181188|ensembl:ENSP00000367868	psi-mi:sqt1_yeast(display_long)|uniprotkb:YIB12W(orf name)|uniprotkb:YIR012W(locus name)|uniprotkb:SQT1(gene name)|psi-mi:SQT1(display_short)	psi-mi:q8n7w2-2(display_long)|uniprotkb:C10orf30(gene name synonym)|uniprotkb:BEND7(gene name)|psi-mi:BEND7(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11527362|imex:IM-24995-525	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012277.1|sgd:S000001451|ensemblfungi:YIR012W_mRNA(transcript)|ensemblfungi:YIR012W(gene)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|rcsb pdb:4ZOV|rcsb pdb:4ZOX|rcsb pdb:5AMS|dip:DIP-2508N|mint:P35184|sgd:YIR012W(identity)	ensembl:ENSG00000165626(gene)|ensembl:ENST00000378605(transcript)|intact:EBI-743382(isoform-parent)|uniprotkb:Q8N7W2-2(isoform-parent)|entrezgene/locuslink:222389(identity)	-	crc64:981D566076B0C881	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:u/Q5uAjR85ZD3op0nHiN20IVCLY559292	rogid:p6qrTn80hLyVU0W2Tvwn50Q4m5I9606	intact-crc:F764D5A757738D50|rigid:toOVjX2vGMz6qqn4DYa1Ab6pYvg	false	-	sufficient binding region:10-374	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q99750	uniprotkb:P35184	intact:EBI-724076|ensembl:ENSP00000230321|ensembl:ENSP00000362142	intact:EBI-17971|uniprotkb:D6VVU2|ensemblfungi:YIR012W	psi-mi:mdfi_human(display_long)|uniprotkb:Myogenic repressor I-mf(gene name synonym)|uniprotkb:MDFI(gene name)|psi-mi:MDFI(display_short)	psi-mi:sqt1_yeast(display_long)|uniprotkb:YIB12W(orf name)|uniprotkb:YIR012W(locus name)|uniprotkb:SQT1(gene name)|psi-mi:SQT1(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11527391|imex:IM-24995-528	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005577.1|ensembl:ENSG00000112559(gene)|ensembl:ENST00000230321(transcript)|ensembl:ENST00000373051(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR026134|mint:Q99750|refseq:NP_001287733.1|refseq:NP_001287734.1|refseq:NP_001287735.1|entrezgene/locuslink:4188(identity)	refseq:NP_012277.1|sgd:S000001451|ensemblfungi:YIR012W_mRNA(transcript)|ensemblfungi:YIR012W(gene)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|rcsb pdb:4ZOV|rcsb pdb:4ZOX|rcsb pdb:5AMS|dip:DIP-2508N|mint:P35184|sgd:YIR012W(identity)	-	-	crc64:981D566076B0C881	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:V3vU0fihMOW18DMHAiDbuZ3asNU9606	rogid:u/Q5uAjR85ZD3op0nHiN20IVCLY559292	intact-crc:888C54FE4DEB7A1D|rigid:m98TxjikmR5tLdYm+xJ8H80jw/s	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P19012	uniprotkb:P36009	intact:EBI-739566|uniprotkb:Q53XV8|uniprotkb:Q9BUG4|uniprotkb:B3KQY1|uniprotkb:B3KRA2|uniprotkb:E0CX14|ensembl:ENSP00000254043|ensembl:ENSP00000377546	intact:EBI-5844|ensemblfungi:YKL078W|uniprotkb:Q07040|uniprotkb:D6VXK9	psi-mi:k1c15_human(display_long)|uniprotkb:KRT15(gene name)|psi-mi:KRT15(display_short)|uniprotkb:KRTB(gene name synonym)|uniprotkb:Cytokeratin-15(gene name synonym)|uniprotkb:Keratin-15(gene name synonym)	psi-mi:dhr2_yeast(display_long)|uniprotkb:DHR2(gene name)|psi-mi:DHR2(display_short)|uniprotkb:YKL078W(locus name)|uniprotkb:YKL408(orf name)|uniprotkb:DEAH box RNA helicase DHR2(gene name synonym)|uniprotkb:Helicase JA2(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11527489|imex:IM-24995-538	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002266.2|ensembl:ENSG00000171346(gene)|ensembl:ENST00000254043(transcript)|ensembl:ENST00000393976(transcript)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0008544"(epidermis development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097110"(scaffold protein binding)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR039008|mint:P19012|reactome:R-HSA-6805567|reactome:R-HSA-6809371|entrezgene/locuslink:3866(identity)	ensemblfungi:YKL078W(gene)|ensemblfungi:YKL078W_mRNA(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|refseq:NP_012845.1|sgd:S000001561|dip:DIP-6424N|mint:P36009|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|sgd:YKL078W(identity)	-	-	crc64:AAFA78B5F6215D89	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:WrZQBYQvrWcfrR5ojWXrXp6spPE9606	rogid:UneKv9+4eIsC09fOzm8AvKCOCVs559292	intact-crc:9AEC0B28EFD118CA|rigid:NaREkejE2qJ2se3b6PCZiveu60Q	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q969G2	uniprotkb:P36001	intact:EBI-2865388|uniprotkb:Q8NHM1|uniprotkb:Q969W2|uniprotkb:Q8TCJ1|uniprotkb:Q8NHE0|uniprotkb:Q8WWX2|ensembl:ENSP00000263726	intact:EBI-2083615|uniprotkb:D6VX64|ensemblfungi:YKL132C	psi-mi:lhx4_human(display_long)|uniprotkb:LHX4(gene name)|psi-mi:LHX4(display_short)	psi-mi:folc_yeast(display_long)|uniprotkb:RMA1(gene name)|psi-mi:RMA1(display_short)|uniprotkb:Folylpoly-gamma-glutamate synthetase(gene name synonym)|uniprotkb:Tetrahydrofolylpolyglutamate synthase(gene name synonym)|uniprotkb:YKL132C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11527480|imex:IM-24995-537	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_203129.1|dip:DIP-29454N|ensembl:ENSG00000121454(gene)|ensembl:ENST00000263726(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001890"(placenta development)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0021526"(medial motor column neuron differentiation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|mint:Q969G2|rcsb pdb:5HOD|reactome:R-HSA-9010553|entrezgene/locuslink:89884(identity)	refseq:NP_012790.1|sgd:S000001615|interpro:IPR001645(Folylpolyglutamate synthetase)|interpro:IPR018109|mint:P36001|interpro:IPR036565|interpro:IPR036615|ensemblfungi:YKL132C(gene)|ensemblfungi:YKL132C_mRNA(transcript)|go:"GO:0004326"(tetrahydrofolylpolyglutamate synthase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0008841"(dihydrofolate synthase activity)|go:"GO:0009396"(folic acid-containing compound biosynthetic process)|go:"GO:0016881"(acid-amino acid ligase activity)|go:"GO:0046872"(metal ion binding)|sgd:YKL132C(identity)	-	crc64:6499F38E78B79FD1	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:dCB3WgIBMdi0nNvaCFaioh+F9sw9606	rogid:pL0jH0sRdb39RE+KmXGMCnXkFZw559292	intact-crc:57B02CD8C27EB5A7|rigid:ojXQqv3rN6YPRhA+cjelvDLhNDo	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P35719	uniprotkb:P07954	intact:EBI-16255|ensemblfungi:YKL142W|uniprotkb:D6VX54	intact:EBI-1050358|uniprotkb:B1ANK7|ensembl:ENSP00000355518	psi-mi:mrp8_yeast(display_long)|uniprotkb:MRP8(gene name)|psi-mi:MRP8(display_short)|uniprotkb:YKL3(orf name)|uniprotkb:YKL142W(locus name)	psi-mi:fumh_human(display_long)|uniprotkb:FH(gene name)|psi-mi:FH(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11527471|imex:IM-24995-536	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012780.1|sgd:S000001625|ensemblfungi:YKL142W(gene)|go:"GO:0005737"(cytoplasm)|interpro:IPR012917(Ribosomal protein MRP8, mitochondrial)|ensemblfungi:YKL142W_mRNA(transcript)|dip:DIP-1437N|mint:P35719|sgd:YKL142W(identity)	refseq:NP_000134.2|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006106"(fumarate metabolic process)|go:"GO:0006108"(malate metabolic process)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042393"(histone binding)|go:"GO:0045239"(tricarboxylic acid cycle enzyme complex)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0070062"(extracellular exosome)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR000362(Fumarate lyase)|interpro:IPR005677(Fumarate hydratase, class II)|ensembl:ENSG00000091483(gene)|interpro:IPR008948(L-Aspartase-like)|interpro:IPR018951|ensembl:ENST00000366560(transcript)|interpro:IPR020557|interpro:IPR022761|go:"GO:0000050"(urea cycle)|interpro:IPR024083|mint:P07954|rcsb pdb:3E04|go:"GO:0000415"(negative regulation of histone H3-K36 methylation)|rcsb pdb:5D6B|go:"GO:0000821"(regulation of arginine metabolic process)|rcsb pdb:5UPP|rcsb pdb:6EBT|rcsb pdb:6V8F|rcsb pdb:6VBE|go:"GO:0004333"(fumarate hydratase activity)|reactome:R-HSA-71403|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|dip:DIP-46920N|entrezgene/locuslink:2271(identity)	-	crc64:CCAD54B7581A5ABE	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:xrv86SZgOYjf+CaLkNdme45DC9s559292	rogid:Jukx6wt0vi49nxgaTzdz5x1Q2Mc9606	intact-crc:CBF80CA0BF2B3C9F|rigid:quZA2L8oYW5/rFS9odvmcSs3UZc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P63279	uniprotkb:P35192	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	intact:EBI-10346|ensemblfungi:YMR021C|uniprotkb:D6VZJ5|uniprotkb:E9P8Z5	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:mac1_yeast(display_long)|uniprotkb:MAC1(gene name)|psi-mi:MAC1(display_short)|uniprotkb:CUA1(gene name synonym)|uniprotkb:YMR021C(locus name)|uniprotkb:YM9711.11C(orf name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11527429|imex:IM-24995-532	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N|entrezgene/locuslink:7329(identity)	refseq:NP_013734.1|sgd:S000004623|ensemblfungi:YMR021C(gene)|ensemblfungi:YMR021C_mRNA(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005507"(copper ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0006878"(cellular copper ion homeostasis)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR036395|interpro:IPR001083(Copper fist DNA-binding)|dip:DIP-4851N|sgd:YMR021C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	rogid:qm/hIB5eRjjEZv9H+Zng34N5ops559292	intact-crc:F7979A7731F3DCB9|rigid:FKAl0qhsW7XehKRyWFSuNYvGXFk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P35719	uniprotkb:A0A024R4Q5	intact:EBI-16255|ensemblfungi:YKL142W|uniprotkb:D6VX54	intact:EBI-11527449	psi-mi:mrp8_yeast(display_long)|uniprotkb:MRP8(gene name)|psi-mi:MRP8(display_short)|uniprotkb:YKL3(orf name)|uniprotkb:YKL142W(locus name)	psi-mi:a0a024r4q5_human(display_long)|uniprotkb:hCG_20946(orf name)|uniprotkb:TFPT(gene name)|psi-mi:TFPT(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11527447|imex:IM-24995-534	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012780.1|sgd:S000001625|ensemblfungi:YKL142W(gene)|go:"GO:0005737"(cytoplasm)|interpro:IPR012917(Ribosomal protein MRP8, mitochondrial)|ensemblfungi:YKL142W_mRNA(transcript)|dip:DIP-1437N|mint:P35719|sgd:YKL142W(identity)	refseq:NP_037474.1|interpro:IPR033555|go:"GO:0005654"(nucleoplasm)|go:"GO:0006915"(apoptotic process)|entrezgene/locuslink:29844(identity)	-	crc64:CCAD54B7581A5ABE	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:xrv86SZgOYjf+CaLkNdme45DC9s559292	rogid:juI/3gZemjc0hnXDJ9J+bIQ9pBw9606	intact-crc:8D6F8DE4F51EE631|rigid:t2kvQdRlFcuC5B3VyNAvAD0B5P0	false	-	sufficient binding region:10-253	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P35192	uniprotkb:Q8N9N5-2	intact:EBI-10346|ensemblfungi:YMR021C|uniprotkb:D6VZJ5|uniprotkb:E9P8Z5	intact:EBI-11524452|ensembl:ENSP00000347125	psi-mi:mac1_yeast(display_long)|uniprotkb:MAC1(gene name)|psi-mi:MAC1(display_short)|uniprotkb:CUA1(gene name synonym)|uniprotkb:YMR021C(locus name)|uniprotkb:YM9711.11C(orf name)	psi-mi:q8n9n5-2(display_long)|uniprotkb:BANP(gene name)|psi-mi:BANP(display_short)|uniprotkb:BEN domain-containing protein 1(gene name synonym)|uniprotkb:BEND1(gene name synonym)|uniprotkb:Btg3-associated nuclear protein(gene name synonym)|uniprotkb:SMAR1(gene name synonym)|uniprotkb:Scaffold/matrix-associated region-1-binding protein(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11527438|imex:IM-24995-533	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013734.1|sgd:S000004623|ensemblfungi:YMR021C(gene)|ensemblfungi:YMR021C_mRNA(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005507"(copper ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0006878"(cellular copper ion homeostasis)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR036395|interpro:IPR001083(Copper fist DNA-binding)|dip:DIP-4851N|sgd:YMR021C(identity)	ensembl:ENSG00000172530(gene)|ensembl:ENST00000355022(transcript)|intact:EBI-744695(isoform-parent)|uniprotkb:Q8N9N5-2(isoform-parent)|entrezgene/locuslink:54971(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:qm/hIB5eRjjEZv9H+Zng34N5ops559292	rogid:ESe6iCAhvq+i57fQHz3rGyg6UOo9606	intact-crc:974E0DF5D296374F|rigid:Ton7BCxl/TrkXRCpHGyZ531A/dM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O95273	uniprotkb:P35719	intact:EBI-748961|uniprotkb:A8K3Q0|uniprotkb:A8K3U2|uniprotkb:Q6ZQN9|uniprotkb:Q7Z519|uniprotkb:Q8NBS7|uniprotkb:Q8NBY2|uniprotkb:Q9NS19|uniprotkb:Q9NYH3|uniprotkb:Q9UHX9|ensembl:ENSP00000300213	intact:EBI-16255|ensemblfungi:YKL142W|uniprotkb:D6VX54	psi-mi:ccdb1_human(display_long)|uniprotkb:Grap2 and cyclin-D-interacting protein(gene name synonym)|uniprotkb:Human homolog of Maid(gene name synonym)|uniprotkb:CCNDBP1(gene name)|psi-mi:CCNDBP1(display_short)|uniprotkb:DIP1(gene name synonym)|uniprotkb:GCIP(gene name synonym)|uniprotkb:HHM(gene name synonym)	psi-mi:mrp8_yeast(display_long)|uniprotkb:MRP8(gene name)|psi-mi:MRP8(display_short)|uniprotkb:YKL3(orf name)|uniprotkb:YKL142W(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11527462|imex:IM-24995-535	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_036274.3|ensembl:ENSG00000166946(gene)|ensembl:ENST00000300213(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0016604"(nuclear body)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR026907|mint:O95273|rcsb pdb:3AY5|entrezgene/locuslink:23582(identity)	refseq:NP_012780.1|sgd:S000001625|ensemblfungi:YKL142W(gene)|go:"GO:0005737"(cytoplasm)|interpro:IPR012917(Ribosomal protein MRP8, mitochondrial)|ensemblfungi:YKL142W_mRNA(transcript)|dip:DIP-1437N|mint:P35719|sgd:YKL142W(identity)	-	-	crc64:CCAD54B7581A5ABE	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Vi9aoFc+Mov6P3X6KGmsTxXqxvM9606	rogid:xrv86SZgOYjf+CaLkNdme45DC9s559292	intact-crc:4C2054C092ECD6E7|rigid:4erpV7VkNjR/NOhLjNIqNdj0S1g	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P36084	uniprotkb:Q8N5R6	intact:EBI-11612|ensemblfungi:YKL074C|uniprotkb:D6VXL2	intact:EBI-740841|intact:EBI-953781|uniprotkb:B3KQ49|uniprotkb:A8K3U4|uniprotkb:A8MPQ6|uniprotkb:A8MV61|uniprotkb:A8MVU9|uniprotkb:Q9H5Q6|uniprotkb:Q8TAX6|intact:EBI-2320546|intact:EBI-11522976	psi-mi:mud2_yeast(display_long)|uniprotkb:MUD2(gene name)|psi-mi:MUD2(display_short)|uniprotkb:YKL358(orf name)|uniprotkb:YKL074C(locus name)	psi-mi:ccd33_human(display_long)|uniprotkb:CCDC33(gene name)|psi-mi:CCDC33(display_short)|uniprotkb:Cancer/testis antigen 61(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11527552|imex:IM-24995-545	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0000243"(commitment complex)|go:"GO:0000348"(mRNA branch site recognition)|go:"GO:0003729"(mRNA binding)|go:"GO:0008187"(poly-pyrimidine tract binding)|go:"GO:0016607"(nuclear speck)|ensemblfungi:YKL074C(gene)|go:"GO:0030628"(pre-mRNA 3'-splice site binding)|go:"GO:0045131"(pre-mRNA branch point binding)|go:"GO:0071004"(U2-type prespliceosome)|ensemblfungi:YKL074C_mRNA(transcript)|go:"GO:0089701"(U2AF complex)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|refseq:NP_012849.1|sgd:S000001557|mint:P36084|dip:DIP-758N|sgd:YKL074C(identity)	refseq:NP_079331.3|interpro:IPR000008(C2 calcium-dependent membrane targeting)|go:"GO:0005777"(peroxisome)|refseq:NP_001274110.1|refseq:NP_877592.2|mint:Q8N5R6|interpro:IPR035892|interpro:IPR039889|entrezgene/locuslink:80125(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2021/11/30	rogid:l/aBULMxdezuufNxUE5qqnYEN1Y559292	rogid:eEIn7pQyfdHWx8TeLJpYy0i/gww9606	intact-crc:CB7ED8D09262B8EA|rigid:9jA2zOpeNU+zSpP2ttF0RE5qAYg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O43765	uniprotkb:P36057	intact:EBI-347996|ensembl:ENSP00000221566|ensembl:ENSP00000503397|ensembl:ENSP00000504495|uniprotkb:Q9BTZ9|intact:EBI-1045243|uniprotkb:Q6FIA9|uniprotkb:D6W610	intact:EBI-18091|uniprotkb:D6VX44|ensemblfungi:YKL154W	psi-mi:sgta_human(display_long)|uniprotkb:SGTA(gene name)|psi-mi:SGTA(display_short)|uniprotkb:SGT(gene name synonym)|uniprotkb:Alpha-SGT(gene name synonym)|uniprotkb:Vpu-binding protein(gene name synonym)|uniprotkb:SGT1(gene name synonym)	psi-mi:srpb_yeast(display_long)|uniprotkb:SRP102(gene name)|psi-mi:SRP102(display_short)|uniprotkb:YKL609(orf name)|uniprotkb:YKL154W(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11527543|imex:IM-24995-544	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:4CPG|rcsb pdb:4GOD|rcsb pdb:4GOE|rcsb pdb:4GOF|reactome:R-HSA-9609523|rcsb pdb:2VYI|ensembl:ENSG00000104969(gene)|ensembl:ENST00000221566(transcript)|ensembl:ENST00000676943(transcript)|ensembl:ENST00000677149(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072380"(TRC complex)|go:"GO:0098850"(extrinsic component of synaptic vesicle membrane)|go:"GO:1903070"(negative regulation of ER-associated ubiquitin-dependent protein catabolic process)|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)|go:"GO:1903646"(positive regulation of chaperone-mediated protein folding)|go:"GO:1904288"(BAT3 complex binding)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR032374|mint:O43765|refseq:XP_011526480.1|refseq:NP_003012.1|entrezgene/locuslink:6449(identity)	refseq:NP_012768.1|sgd:S000001637|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045047"(protein targeting to ER)|interpro:IPR019009|interpro:IPR027417|rcsb pdb:1NRJ|rcsb pdb:2GED|ensemblfungi:YKL154W(gene)|ensemblfungi:YKL154W_mRNA(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005047"(signal recognition particle binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005785"(signal recognition particle receptor complex)|dip:DIP-4753N|sgd:YKL154W(identity)	-	-	crc64:EA4AE9126B2A04B5	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:r/Cyj4UJk/cS8QdrbjhTZMPCigI9606	rogid:PWBNmZgucFpCtOusxQ3OU1ZvAQ4559292	intact-crc:EE7CE54FB8995A8A|rigid:5IGU5+F3p/NfHYJeS33OkYCUrb8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8NEU8	uniprotkb:P36019	intact:EBI-741261|ensembl:ENSP00000258530|uniprotkb:Q8N4R7|uniprotkb:Q9NVL2|uniprotkb:B7Z411|uniprotkb:B7Z4B0|uniprotkb:F5GZG0|uniprotkb:F8W1P5	intact:EBI-29415|uniprotkb:Q45TZ5|uniprotkb:D6W187|ensemblfungi:YNL093W	psi-mi:dp13b_human(display_long)|uniprotkb:Adapter protein containing PH domain, PTB domain and leucine zipper motif 2(gene name synonym)|uniprotkb:APPL2(gene name)|psi-mi:APPL2(display_short)|uniprotkb:DIP13B(gene name synonym)	psi-mi:ypt53_yeast(display_long)|uniprotkb:YPT53(gene name)|psi-mi:YPT53(display_short)|uniprotkb:N2223(orf name)|uniprotkb:YNL093W(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11527534|imex:IM-24995-543	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0002024"(diet induced thermogenesis)|go:"GO:0005634"(nucleus)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0009631"(cold acclimation)|go:"GO:0010008"(endosome membrane)|go:"GO:0010762"(regulation of fibroblast migration)|go:"GO:0016020"(membrane)|go:"GO:0023052"(signaling)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032009"(early phagosome)|go:"GO:0032587"(ruffle membrane)|go:"GO:0033211"(adiponectin-activated signaling pathway)|go:"GO:0034143"(regulation of toll-like receptor 4 signaling pathway)|go:"GO:0035091"(phosphatidylinositol binding)|ensembl:ENSG00000136044(gene)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0036186"(early phagosome membrane)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|ensembl:ENST00000258530(transcript)|go:"GO:0044354"(macropinosome)|go:"GO:0001726"(ruffle)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000178"(negative regulation of neural precursor cell proliferation)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR027267|mint:Q8NEU8|rcsb pdb:4H8S|rcsb pdb:5C5B|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0046322"(negative regulation of fatty acid oxidation)|go:"GO:0046325"(negative regulation of glucose import)|go:"GO:0050768"(negative regulation of neurogenesis)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060100"(positive regulation of phagocytosis, engulfment)|go:"GO:0070062"(extracellular exosome)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1900016"(negative regulation of cytokine production involved in inflammatory response)|go:"GO:1900077"(negative regulation of cellular response to insulin stimulus)|go:"GO:1905303"(positive regulation of macropinocytosis)|go:"GO:1905451"(positive regulation of Fc-gamma receptor signaling pathway involved in phagocytosis)|refseq:NP_060641.2|refseq:XP_016875042.1|refseq:XP_016875041.1|refseq:NP_001238833.1|refseq:NP_001238834.1|entrezgene/locuslink:55198(identity)	sgd:S000005037|refseq:NP_014306.3|dip:DIP-2025N|ensemblfungi:YNL093W(gene)|ensemblfungi:YNL093W_mRNA(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0006897"(endocytosis)|go:"GO:0012505"(endomembrane system)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|sgd:YNL093W(identity)	-	-	crc64:ABA1D926D1EE9F68	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:8T+Y5phqYZ2On/CsfVVsOChSJNM9606	rogid:2IDdF9ESvaxekyjmAzuRL9vMYJ8559292	intact-crc:14F37DD1C5205948|rigid:Vsh+AYUv89QAliyy3oxOk5Jo9I0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P36009	uniprotkb:Q13422-7	intact:EBI-5844|ensemblfungi:YKL078W|uniprotkb:Q07040|uniprotkb:D6VXK9	intact:EBI-11522367|ensembl:ENSP00000352123|ensembl:ENSP00000413025	psi-mi:dhr2_yeast(display_long)|uniprotkb:DHR2(gene name)|psi-mi:DHR2(display_short)|uniprotkb:YKL078W(locus name)|uniprotkb:YKL408(orf name)|uniprotkb:DEAH box RNA helicase DHR2(gene name synonym)|uniprotkb:Helicase JA2(gene name synonym)	psi-mi:q13422-7(display_long)|uniprotkb:IKZF1(gene name)|psi-mi:IKZF1(display_short)|uniprotkb:IK1(gene name synonym)|uniprotkb:IKAROS(gene name synonym)|uniprotkb:Ikaros family zinc finger protein 1(gene name synonym)|uniprotkb:LYF1(gene name synonym)|uniprotkb:Lymphoid transcription factor LyF-1(gene name synonym)|uniprotkb:ZNFN1A1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11527498|imex:IM-24995-539	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YKL078W(gene)|ensemblfungi:YKL078W_mRNA(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|refseq:NP_012845.1|sgd:S000001561|dip:DIP-6424N|mint:P36009|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|sgd:YKL078W(identity)	intact:EBI-745305(isoform-parent)|ensembl:ENSG00000185811(gene)|ensembl:ENST00000359197(transcript)|ensembl:ENST00000439701(transcript)|uniprotkb:Q13422-7(isoform-parent)|entrezgene/locuslink:10320(identity)	-	crc64:AAFA78B5F6215D89	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:UneKv9+4eIsC09fOzm8AvKCOCVs559292	rogid:ou/ovXYoMneBNVp4pj38VxenfyY9606	intact-crc:03E48EE4D88DC000|rigid:FDHu/DRyfeVGom6qYipoARsDdRE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P36018	uniprotkb:Q8NEU8	intact:EBI-29407|uniprotkb:D6VX79|ensemblfungi:YKR014C	intact:EBI-741261|ensembl:ENSP00000258530|uniprotkb:Q8N4R7|uniprotkb:Q9NVL2|uniprotkb:B7Z411|uniprotkb:B7Z4B0|uniprotkb:F5GZG0|uniprotkb:F8W1P5	psi-mi:ypt52_yeast(display_long)|uniprotkb:YPT52(gene name)|psi-mi:YPT52(display_short)|uniprotkb:YK112(orf name)|uniprotkb:YKR014C(locus name)	psi-mi:dp13b_human(display_long)|uniprotkb:Adapter protein containing PH domain, PTB domain and leucine zipper motif 2(gene name synonym)|uniprotkb:APPL2(gene name)|psi-mi:APPL2(display_short)|uniprotkb:DIP13B(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11527516|imex:IM-24995-541	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012939.1|sgd:S000001722|dip:DIP-2121N|mint:P36018|ensemblfungi:YKR014C(gene)|ensemblfungi:YKR014C_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0006897"(endocytosis)|go:"GO:0012505"(endomembrane system)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0036258"(multivesicular body assembly)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|reactome:R-SCE-6798695|reactome:R-SCE-8856828|reactome:R-SCE-8873719|reactome:R-SCE-8876198|reactome:R-SCE-983231|sgd:YKR014C(identity)	go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0002024"(diet induced thermogenesis)|go:"GO:0005634"(nucleus)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0009631"(cold acclimation)|go:"GO:0010008"(endosome membrane)|go:"GO:0010762"(regulation of fibroblast migration)|go:"GO:0016020"(membrane)|go:"GO:0023052"(signaling)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032009"(early phagosome)|go:"GO:0032587"(ruffle membrane)|go:"GO:0033211"(adiponectin-activated signaling pathway)|go:"GO:0034143"(regulation of toll-like receptor 4 signaling pathway)|go:"GO:0035091"(phosphatidylinositol binding)|ensembl:ENSG00000136044(gene)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0036186"(early phagosome membrane)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|ensembl:ENST00000258530(transcript)|go:"GO:0044354"(macropinosome)|go:"GO:0001726"(ruffle)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000178"(negative regulation of neural precursor cell proliferation)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR027267|mint:Q8NEU8|rcsb pdb:4H8S|rcsb pdb:5C5B|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0046322"(negative regulation of fatty acid oxidation)|go:"GO:0046325"(negative regulation of glucose import)|go:"GO:0050768"(negative regulation of neurogenesis)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060100"(positive regulation of phagocytosis, engulfment)|go:"GO:0070062"(extracellular exosome)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1900016"(negative regulation of cytokine production involved in inflammatory response)|go:"GO:1900077"(negative regulation of cellular response to insulin stimulus)|go:"GO:1905303"(positive regulation of macropinocytosis)|go:"GO:1905451"(positive regulation of Fc-gamma receptor signaling pathway involved in phagocytosis)|refseq:NP_060641.2|refseq:XP_016875042.1|refseq:XP_016875041.1|refseq:NP_001238833.1|refseq:NP_001238834.1|entrezgene/locuslink:55198(identity)	-	crc64:34AB2FFE38697261	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:KZ9/F9Ilto2oDHiPHffIM2gcVnY559292	rogid:8T+Y5phqYZ2On/CsfVVsOChSJNM9606	intact-crc:AA33B9CC44923305|rigid:lHzj+ZFvH2+kCKWOePtCz1O1SO8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96BR9	uniprotkb:P36009	intact:EBI-742740|uniprotkb:Q8IUL5|uniprotkb:Q8IWR9|uniprotkb:Q8N2Y5|uniprotkb:Q96BX0|ensembl:ENSP00000362609	intact:EBI-5844|ensemblfungi:YKL078W|uniprotkb:Q07040|uniprotkb:D6VXK9	psi-mi:zbt8a_human(display_long)|uniprotkb:ZBTB8A(gene name)|psi-mi:ZBTB8A(display_short)|uniprotkb:BOZF1(gene name synonym)|uniprotkb:BTB/POZ and zinc-finger domain-containing factor(gene name synonym)|uniprotkb:BTB/POZ and zinc-finger domains factor on chromosome 1(gene name synonym)	psi-mi:dhr2_yeast(display_long)|uniprotkb:DHR2(gene name)|psi-mi:DHR2(display_short)|uniprotkb:YKL078W(locus name)|uniprotkb:YKL408(orf name)|uniprotkb:DEAH box RNA helicase DHR2(gene name synonym)|uniprotkb:Helicase JA2(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11527507|imex:IM-24995-540	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000160062(gene)|ensembl:ENST00000373510(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|refseq:NP_001035531.2|refseq:NP_001278425.1|entrezgene/locuslink:653121(identity)	ensemblfungi:YKL078W(gene)|ensemblfungi:YKL078W_mRNA(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|refseq:NP_012845.1|sgd:S000001561|dip:DIP-6424N|mint:P36009|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|sgd:YKL078W(identity)	-	-	crc64:AAFA78B5F6215D89	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:tsrPT2tHvuBryODKgRXnceXz9s09606	rogid:UneKv9+4eIsC09fOzm8AvKCOCVs559292	intact-crc:5E5AF1D0B4A15DB1|rigid:WbBEdlgDyAgMyDVt3Br/S+A2t+E	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P36019	uniprotkb:Q8N612	intact:EBI-29415|uniprotkb:Q45TZ5|uniprotkb:D6W187|ensemblfungi:YNL093W	intact:EBI-742137|uniprotkb:Q9C0A4|uniprotkb:Q9H0N3|uniprotkb:Q9H624|intact:EBI-28987623|ensembl:ENSP00000416918	psi-mi:ypt53_yeast(display_long)|uniprotkb:YPT53(gene name)|psi-mi:YPT53(display_short)|uniprotkb:N2223(orf name)|uniprotkb:YNL093W(locus name)	psi-mi:fhi1b_human(display_long)|uniprotkb:FHIP1B(gene name)|psi-mi:FHIP1B(display_short)|uniprotkb:C11orf56(gene name synonym)|uniprotkb:FAM160A2(gene name synonym)|uniprotkb:FTS and Hook-interacting protein(gene name synonym)|uniprotkb:KIAA1759(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11527525|imex:IM-24995-542	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005037|refseq:NP_014306.3|dip:DIP-2025N|ensemblfungi:YNL093W(gene)|ensemblfungi:YNL093W_mRNA(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0006897"(endocytosis)|go:"GO:0012505"(endomembrane system)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|sgd:YNL093W(identity)	refseq:NP_001092264.1|refseq:NP_115503.2|refseq:XP_011518699.1|ensembl:ENST00000265978|ensembl:ENSP00000265978|ensembl:ENSP00000416918|refseq:XP_006718406.1|ensembl:ENSG00000051009(gene)|ensembl:ENST00000449352(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0007032"(endosome organization)|go:"GO:0007040"(lysosome organization)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0015031"(protein transport)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0070695"(FHF complex)|go:"GO:1905719"(protein localization to perinuclear region of cytoplasm)|interpro:IPR019384|entrezgene/locuslink:84067(identity)	-	crc64:ABA1D926D1EE9F68	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:2IDdF9ESvaxekyjmAzuRL9vMYJ8559292	rogid:sHMptILNXi94k81XAjE55r829C49606	intact-crc:078F8D90AAB34201|rigid:LJcwCYkDrCltO+woa97BRuKD/8U	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96BD8	uniprotkb:P36118	intact:EBI-741854|uniprotkb:B2R9Y6|uniprotkb:B4E0P4|ensembl:ENSP00000285116|ensembl:ENSP00000381470|ensembl:ENSP00000458992|ensembl:ENSP00000478259	intact:EBI-26362|uniprotkb:D6VX87|ensemblfungi:YKR022C	psi-mi:ska1_human(display_long)|uniprotkb:SKA1(gene name)|psi-mi:SKA1(display_short)|uniprotkb:C18orf24(gene name synonym)	psi-mi:ntr2_yeast(display_long)|uniprotkb:YKR022C(locus name)|uniprotkb:Nineteen complex-related protein 2(gene name synonym)|uniprotkb:NTR2(gene name)|psi-mi:NTR2(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11527617|imex:IM-24995-552	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001034624.1|refseq:NP_659497.1|ensembl:ENSG00000154839(gene)|ensembl:ENSG00000262634(gene)|ensembl:ENST00000285116(transcript)|ensembl:ENST00000398452(transcript)|ensembl:ENST00000571751(transcript)|ensembl:ENST00000616604(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000940"(outer kinetochore)|go:"GO:0005829"(cytosol)|go:"GO:0005876"(spindle microtubule)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008017"(microtubule binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0031110"(regulation of microtubule polymerization or depolymerization)|go:"GO:0051301"(cell division)|go:"GO:0072686"(mitotic spindle)|interpro:IPR009829(Protein of unknown function DUF1395)|interpro:IPR042031|mint:Q96BD8|rcsb pdb:4AJ5|rcsb pdb:4C9Y|rcsb pdb:4CA0|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|entrezgene/locuslink:220134(identity)	sgd:S000001730|refseq:NP_012947.1|mint:P36118|dip:DIP-1924N|ensemblfungi:YKR022C(gene)|ensemblfungi:YKR022C_mRNA(transcript)|go:"GO:0000390"(spliceosomal complex disassembly)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0071008"(U2-type post-mRNA release spliceosomal complex)|interpro:IPR028211|rcsb pdb:5Y88|sgd:YKR022C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Z7y57MeLsUJK0R9JNqHJNBbKr/89606	rogid:q7LBRp/vP0mdE4MGFfqW71T1LQg559292	intact-crc:F4A4C06AFF163268|rigid:aA8MCdVRwzodM3hsX3LdAXASxss	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P36108	uniprotkb:Q96L14	intact:EBI-26574|uniprotkb:D6VXT5|ensemblfungi:YKL002W	intact:EBI-743488	psi-mi:did4_yeast(display_long)|uniprotkb:VPL2(gene name synonym)|uniprotkb:VPS2(gene name synonym)|uniprotkb:VPT14(gene name synonym)|uniprotkb:YKL002W(locus name)|uniprotkb:DID4(gene name)|psi-mi:DID4(display_short)|uniprotkb:CHM2(gene name synonym)|uniprotkb:GRD7(gene name synonym)|uniprotkb:REN1(gene name synonym)|uniprotkb:Vacuolar protein-sorting-associated protein 2(gene name synonym)|uniprotkb:Vacuolar protein-targeting protein 14(gene name synonym)|uniprotkb:ESCRT-III complex subunit VPS2(gene name synonym)	psi-mi:c170l_human(display_long)|uniprotkb:KIAA0470L(gene name synonym)|uniprotkb:CEP170P1(gene name)|psi-mi:CEP170P1(display_short)|uniprotkb:CEP170L(gene name synonym)|uniprotkb:CEP170 pseudogene 1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11527608|imex:IM-24995-551	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012924.2|sgd:S000001485|mint:P36108|dip:DIP-1916N|ensemblfungi:YKL002W(gene)|ensemblfungi:YKL002W_mRNA(transcript)|go:"GO:0000815"(ESCRT III complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005771"(multivesicular body)|go:"GO:0015031"(protein transport)|go:"GO:0032509"(endosome transport via multivesicular body sorting pathway)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0045053"(protein retention in Golgi apparatus)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0070676"(intralumenal vesicle formation)|go:"GO:1904669"(ATP export)|interpro:IPR005024(Snf7)|rcsb pdb:2V6X|rcsb pdb:6AP1|rcsb pdb:6BMF|reactome:R-SCE-1632852|reactome:R-SCE-917729|reactome:R-SCE-9668328|sgd:YKL002W(identity)	interpro:IPR026644|interpro:IPR029300|go:"GO:0042802"(identical protein binding)|entrezgene/locuslink:645455(identity)	-	crc64:200D07DB4C45DCBC	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:iQ8lcGhal3Pt46dwcOkIW2fp/G0559292	rogid:Z/Rium0Kwj3ZUHa4WE5PPksPXdg9606	intact-crc:5280BCF5B860F434|rigid:RYPdLnjN5ZPY/1MSObzNeUAzgKo	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P36086	uniprotkb:P19012	intact:EBI-2343631|uniprotkb:D6VXL5|ensemblfungi:YKL071W	intact:EBI-739566|uniprotkb:Q53XV8|uniprotkb:Q9BUG4|uniprotkb:B3KQY1|uniprotkb:B3KRA2|uniprotkb:E0CX14|ensembl:ENSP00000254043|ensembl:ENSP00000377546	psi-mi:ykh1_yeast(display_long)|uniprotkb:YKL071W(locus name)	psi-mi:k1c15_human(display_long)|uniprotkb:KRT15(gene name)|psi-mi:KRT15(display_short)|uniprotkb:KRTB(gene name synonym)|uniprotkb:Cytokeratin-15(gene name synonym)|uniprotkb:Keratin-15(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11527599|imex:IM-24995-550	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR002347(Glucose/ribitol dehydrogenase)|refseq:NP_012852.1|sgd:S000001554|interpro:IPR036291|ensemblfungi:YKL071W(gene)|ensemblfungi:YKL071W_mRNA(transcript)|go:"GO:0004022"("alcohol dehydrogenase (NAD+) activity")|go:"GO:0005737"(cytoplasm)|go:"GO:0110095"(cellular detoxification of aldehyde)|sgd:YKL071W(identity)	refseq:NP_002266.2|ensembl:ENSG00000171346(gene)|ensembl:ENST00000254043(transcript)|ensembl:ENST00000393976(transcript)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0008544"(epidermis development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097110"(scaffold protein binding)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR039008|mint:P19012|reactome:R-HSA-6805567|reactome:R-HSA-6809371|entrezgene/locuslink:3866(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:9+aUU4I1T7cAMKJgi1qbDD4t+WM559292	rogid:WrZQBYQvrWcfrR5ojWXrXp6spPE9606	intact-crc:1E07D73B61D2D1E6|rigid:yFBCH6y2fAf8NjyZpokQqbWZ0Lk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q08379	uniprotkb:P36084	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	intact:EBI-11612|ensemblfungi:YKL074C|uniprotkb:D6VXL2	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:mud2_yeast(display_long)|uniprotkb:MUD2(gene name)|psi-mi:MUD2(display_short)|uniprotkb:YKL358(orf name)|uniprotkb:YKL074C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11527561|imex:IM-24995-546	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N|entrezgene/locuslink:2801(identity)	go:"GO:0000243"(commitment complex)|go:"GO:0000348"(mRNA branch site recognition)|go:"GO:0003729"(mRNA binding)|go:"GO:0008187"(poly-pyrimidine tract binding)|go:"GO:0016607"(nuclear speck)|ensemblfungi:YKL074C(gene)|go:"GO:0030628"(pre-mRNA 3'-splice site binding)|go:"GO:0045131"(pre-mRNA branch point binding)|go:"GO:0071004"(U2-type prespliceosome)|ensemblfungi:YKL074C_mRNA(transcript)|go:"GO:0089701"(U2AF complex)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|refseq:NP_012849.1|sgd:S000001557|mint:P36084|dip:DIP-758N|sgd:YKL074C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2017/05/26	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	rogid:l/aBULMxdezuufNxUE5qqnYEN1Y559292	intact-crc:5FE1AB77BABE0B2B|rigid:GOJOGcJuewHTPD3FhWtNjgReEgU	false	sufficient binding region:383-1002	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q15415	uniprotkb:P36084	intact:EBI-8642021|uniprotkb:B2R916|intact:MINT-8163253|ensembl:ENSP00000250831|ensembl:ENSP00000307155	intact:EBI-11612|ensemblfungi:YKL074C|uniprotkb:D6VXL2	psi-mi:rby1f_human(display_long)|uniprotkb:RBMY1F(gene name)|psi-mi:RBMY1F(display_short)|uniprotkb:RBMY1J(gene name)|psi-mi:RBMY1J(display_short)|uniprotkb:Y chromosome RNA recognition motif 2(gene name synonym)|uniprotkb:YRRM2(gene name synonym)	psi-mi:mud2_yeast(display_long)|uniprotkb:MUD2(gene name)|psi-mi:MUD2(display_short)|uniprotkb:YKL358(orf name)|uniprotkb:YKL074C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11527581|imex:IM-24995-548	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001290339.1|refseq:NP_001006117.2|refseq:NP_689798.1|ensembl:ENSG00000169800(gene)|ensembl:ENSG00000226941(gene)|ensembl:ENST00000250831(transcript)|ensembl:ENST00000303766(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016607"(nuclear speck)|go:"GO:0042802"(identical protein binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012604(RBM1CTR)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|entrezgene/locuslink:159163(identity)	go:"GO:0000243"(commitment complex)|go:"GO:0000348"(mRNA branch site recognition)|go:"GO:0003729"(mRNA binding)|go:"GO:0008187"(poly-pyrimidine tract binding)|go:"GO:0016607"(nuclear speck)|ensemblfungi:YKL074C(gene)|go:"GO:0030628"(pre-mRNA 3'-splice site binding)|go:"GO:0045131"(pre-mRNA branch point binding)|go:"GO:0071004"(U2-type prespliceosome)|ensemblfungi:YKL074C_mRNA(transcript)|go:"GO:0089701"(U2AF complex)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|refseq:NP_012849.1|sgd:S000001557|mint:P36084|dip:DIP-758N|sgd:YKL074C(identity)	-	comment:mint	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:lEyv+LmtOFRifaC5g6jDlh5WCnM9606	rogid:l/aBULMxdezuufNxUE5qqnYEN1Y559292	intact-crc:8F917F4BB0C5AB5F|rigid:w65kkiCHGlmfPuALqJtb8HWbwCA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O14641	uniprotkb:P36084	intact:EBI-740850|ensembl:ENSP00000005340|uniprotkb:Q53XM0|uniprotkb:D3DTN3	intact:EBI-11612|ensemblfungi:YKL074C|uniprotkb:D6VXL2	psi-mi:dvl2_human(display_long)|uniprotkb:DSH homolog 2(gene name synonym)|uniprotkb:DVL2(gene name)|psi-mi:DVL2(display_short)	psi-mi:mud2_yeast(display_long)|uniprotkb:MUD2(gene name)|psi-mi:MUD2(display_short)|uniprotkb:YKL358(orf name)|uniprotkb:YKL074C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11527572|imex:IM-24995-547	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004413.1|ensembl:ENSG00000004975(gene)|ensembl:ENST00000005340(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005109"(frizzled binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0007507"(heart development)|go:"GO:0016235"(aggresome)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044340"(canonical Wnt signaling pathway involved in regulation of cell proliferation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0150012"(positive regulation of neuron projection arborization)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008341(Dishevelled-2 region)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:O14641|rcsb pdb:2REY|rcsb pdb:3CBX|rcsb pdb:3CBY|rcsb pdb:3CBZ|rcsb pdb:3CC0|rcsb pdb:4WIP|rcsb pdb:5LNP|rcsb pdb:5SUY|rcsb pdb:5SUZ|rcsb pdb:6IW3|rcsb pdb:6JCK|reactome:R-HSA-201681|reactome:R-HSA-201688|reactome:R-HSA-2028269|reactome:R-HSA-4086400|reactome:R-HSA-4608870|reactome:R-HSA-4641258|reactome:R-HSA-4641262|reactome:R-HSA-5099900|reactome:R-HSA-5368598|reactome:R-HSA-5663220|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9673324|ensembl:ENSP00000005340|dip:DIP-34433N|entrezgene/locuslink:1856(identity)	go:"GO:0000243"(commitment complex)|go:"GO:0000348"(mRNA branch site recognition)|go:"GO:0003729"(mRNA binding)|go:"GO:0008187"(poly-pyrimidine tract binding)|go:"GO:0016607"(nuclear speck)|ensemblfungi:YKL074C(gene)|go:"GO:0030628"(pre-mRNA 3'-splice site binding)|go:"GO:0045131"(pre-mRNA branch point binding)|go:"GO:0071004"(U2-type prespliceosome)|ensemblfungi:YKL074C_mRNA(transcript)|go:"GO:0089701"(U2AF complex)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|refseq:NP_012849.1|sgd:S000001557|mint:P36084|dip:DIP-758N|sgd:YKL074C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:2Vdc8oRnT4Mz/j+EXQXrL3AszOc9606	rogid:l/aBULMxdezuufNxUE5qqnYEN1Y559292	intact-crc:E75AAB4B399EFEE7|rigid:cAJUN1S7/U2jmncbEaTbGVNcAVk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q5VWX1	uniprotkb:P36084	intact:EBI-742808|uniprotkb:Q8TCZ4|uniprotkb:Q8N4I4|uniprotkb:A8K7M8|ensembl:ENSP00000281156	intact:EBI-11612|ensemblfungi:YKL074C|uniprotkb:D6VXL2	psi-mi:khdr2_human(display_long)|uniprotkb:SLM1(gene name synonym)|uniprotkb:Sam68-like mammalian protein 1(gene name synonym)|uniprotkb:KHDRBS2(gene name)|psi-mi:KHDRBS2(display_short)	psi-mi:mud2_yeast(display_long)|uniprotkb:MUD2(gene name)|psi-mi:MUD2(display_short)|uniprotkb:YKL358(orf name)|uniprotkb:YKL074C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11527590|imex:IM-24995-549	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_689901.2|ensembl:ENSG00000112232(gene)|ensembl:ENST00000281156(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008143"("poly(A) binding")|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0017124"(SH3 domain binding)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR032335|interpro:IPR032571|interpro:IPR036612|reactome:R-HSA-8849468|entrezgene/locuslink:202559(identity)	go:"GO:0000243"(commitment complex)|go:"GO:0000348"(mRNA branch site recognition)|go:"GO:0003729"(mRNA binding)|go:"GO:0008187"(poly-pyrimidine tract binding)|go:"GO:0016607"(nuclear speck)|ensemblfungi:YKL074C(gene)|go:"GO:0030628"(pre-mRNA 3'-splice site binding)|go:"GO:0045131"(pre-mRNA branch point binding)|go:"GO:0071004"(U2-type prespliceosome)|ensemblfungi:YKL074C_mRNA(transcript)|go:"GO:0089701"(U2AF complex)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|refseq:NP_012849.1|sgd:S000001557|mint:P36084|dip:DIP-758N|sgd:YKL074C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:IfFvZO2dIAo0Sdx+BUb5c8F7aQY9606	rogid:l/aBULMxdezuufNxUE5qqnYEN1Y559292	intact-crc:833271D82398C70D|rigid:dOhlVPfRR+6wCHG1eO4oovEzEsw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P37263	uniprotkb:Q9H190	intact:EBI-21659|uniprotkb:D6VR87|ensemblfungi:YCR087C-A	intact:EBI-742426|ensembl:ENSP00000371233|uniprotkb:O95892|uniprotkb:Q5W0X1|uniprotkb:Q9BZ42|uniprotkb:Q9H567|uniprotkb:Q9NRY8|intact:EBI-28983470|ensembl:ENSP00000342935|ensembl:ENSP00000354013	psi-mi:yc16_yeast(display_long)|uniprotkb:YCRX16C(orf name)|uniprotkb:YCR087C-A(locus name)	psi-mi:sdcb2_human(display_long)|uniprotkb:Similar to TACIP18(gene name synonym)|uniprotkb:SDCBP2(gene name)|psi-mi:SDCBP2(display_short)|uniprotkb:SITAC18(gene name synonym)|uniprotkb:Syndecan-binding protein 2(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11527674|imex:IM-24995-558	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010011.1|sgd:S000007223|mint:P37263|dip:DIP-4536N|ensemblfungi:YCR087C-A(gene)|ensemblfungi:YCR087C-A_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR014898(Zinc finger, C2H2, LYAR-type)|interpro:IPR036236|interpro:IPR039999|sgd:YCR087C-A(identity)	refseq:NP_001186713.1|refseq:NP_056500.2|refseq:NP_536737.3|ensembl:ENSP00000342935|ensembl:ENSP00000354013|ensembl:ENST00000381808|ensembl:ENSP00000371229|ensembl:ENSP00000371233|ensembl:ENSG00000125775(gene)|ensembl:ENST00000360779(transcript)|ensembl:ENST00000381812(transcript)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007399"(nervous system development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016607"(nuclear speck)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046907"(intracellular transport)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036034|interpro:IPR041489|ensembl:ENST00000339987(transcript)|entrezgene/locuslink:27111(identity)	-	crc64:B5B3B4CA37B82042	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:I7iIzRqPZAKdWQSe/IeGsW0qQcU559292	rogid:vlEtVZkwLTte5PJ4i8ce+SwE/4Y9606	intact-crc:AE743E8AC5959615|rigid:GZKCUp0YggGGRChHC1eqHtSHdEc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q969J2	uniprotkb:P37263	intact:EBI-2818641|uniprotkb:B2RE32|uniprotkb:Q5U7L4|intact:EBI-28979011|ensembl:ENSP00000366509	intact:EBI-21659|uniprotkb:D6VR87|ensemblfungi:YCR087C-A	psi-mi:zksc4_human(display_long)|uniprotkb:ZKSCAN4(gene name)|psi-mi:ZKSCAN4(display_short)|uniprotkb:ZNF307(gene name synonym)|uniprotkb:ZNF427(gene name synonym)|uniprotkb:P373c6.1(gene name synonym)|uniprotkb:Zinc finger protein 307(gene name synonym)|uniprotkb:Zinc finger protein 427(gene name synonym)	psi-mi:yc16_yeast(display_long)|uniprotkb:YCRX16C(orf name)|uniprotkb:YCR087C-A(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11527665|imex:IM-24995-557	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_061983.2|ensembl:ENSP00000366509|ensembl:ENSG00000187626(gene)|ensembl:ENST00000377294(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|interpro:IPR038269|mint:Q969J2|reactome:R-HSA-212436|refseq:XP_005249152.1|entrezgene/locuslink:387032(identity)	refseq:NP_010011.1|sgd:S000007223|mint:P37263|dip:DIP-4536N|ensemblfungi:YCR087C-A(gene)|ensemblfungi:YCR087C-A_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR014898(Zinc finger, C2H2, LYAR-type)|interpro:IPR036236|interpro:IPR039999|sgd:YCR087C-A(identity)	-	-	crc64:B5B3B4CA37B82042	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:5TWhAtzfmCXHkOSbjKwjgLIsCcs9606	rogid:I7iIzRqPZAKdWQSe/IeGsW0qQcU559292	intact-crc:C182AE87E8495EB3|rigid:sgHcAG6ilUhpQfZrKLC6ENwANsc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P63279	uniprotkb:P37263	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	intact:EBI-21659|uniprotkb:D6VR87|ensemblfungi:YCR087C-A	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:yc16_yeast(display_long)|uniprotkb:YCRX16C(orf name)|uniprotkb:YCR087C-A(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11527656|imex:IM-24995-556	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N|entrezgene/locuslink:7329(identity)	refseq:NP_010011.1|sgd:S000007223|mint:P37263|dip:DIP-4536N|ensemblfungi:YCR087C-A(gene)|ensemblfungi:YCR087C-A_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR014898(Zinc finger, C2H2, LYAR-type)|interpro:IPR036236|interpro:IPR039999|sgd:YCR087C-A(identity)	-	-	crc64:B5B3B4CA37B82042	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	rogid:I7iIzRqPZAKdWQSe/IeGsW0qQcU559292	intact-crc:9B605B7CEDC2A0C9|rigid:Qck8S7kbrP/Hrd/Os64j6Sm+l40	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P37263	uniprotkb:Q9HCM9-2	intact:EBI-21659|uniprotkb:D6VR87|ensemblfungi:YCR087C-A	intact:EBI-11523450|ensembl:ENSP00000365847|ensembl:ENSP00000373095|ensembl:ENSP00000373097|ensembl:ENSP00000379797|ensembl:ENSP00000379800|ensembl:ENSP00000383486|ensembl:ENSP00000387445|ensembl:ENSP00000389198|ensembl:ENSP00000389852|ensembl:ENSP00000392130|ensembl:ENSP00000394353|ensembl:ENSP00000396986|ensembl:ENSP00000398956|ensembl:ENSP00000401071|ensembl:ENSP00000401184|ensembl:ENSP00000404340|ensembl:ENSP00000404904|ensembl:ENSP00000411582|ensembl:ENSP00000412743|ensembl:ENSP00000414525|ensembl:ENSP00000415259	psi-mi:yc16_yeast(display_long)|uniprotkb:YCRX16C(orf name)|uniprotkb:YCR087C-A(locus name)	psi-mi:q9hcm9-2(display_long)|uniprotkb:TRIM39(gene name)|psi-mi:TRIM39(display_short)|uniprotkb:RING finger protein 23(gene name synonym)|uniprotkb:RNF23(gene name synonym)|uniprotkb:TFP(gene name synonym)|uniprotkb:Testis-abundant finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 39(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM39(gene name synonym)|uniprotkb:TIM39beta(isoform synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11527683|imex:IM-24995-559	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010011.1|sgd:S000007223|mint:P37263|dip:DIP-4536N|ensemblfungi:YCR087C-A(gene)|ensemblfungi:YCR087C-A_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR014898(Zinc finger, C2H2, LYAR-type)|interpro:IPR036236|interpro:IPR039999|sgd:YCR087C-A(identity)	intact:EBI-739510(isoform-parent)|ensembl:ENSG00000204599(gene)|ensembl:ENSG00000206495(gene)|ensembl:ENSG00000224994(gene)|ensembl:ENSG00000226437(gene)|ensembl:ENSG00000229929(gene)|ensembl:ENSG00000230308(gene)|ensembl:ENSG00000232839(gene)|ensembl:ENST00000376659(transcript)|ensembl:ENST00000383601(transcript)|ensembl:ENST00000383603(transcript)|ensembl:ENST00000396548(transcript)|ensembl:ENST00000396551(transcript)|ensembl:ENST00000400644(transcript)|ensembl:ENST00000414015(transcript)|ensembl:ENST00000419790(transcript)|ensembl:ENST00000430502(transcript)|ensembl:ENST00000431272(transcript)|ensembl:ENST00000433900(transcript)|ensembl:ENST00000438076(transcript)|ensembl:ENST00000438859(transcript)|ensembl:ENST00000440117(transcript)|ensembl:ENST00000443109(transcript)|ensembl:ENST00000446397(transcript)|ensembl:ENST00000449318(transcript)|ensembl:ENST00000450778(transcript)|ensembl:ENST00000451132(transcript)|ensembl:ENST00000452705(transcript)|ensembl:ENST00000458607(transcript)|uniprotkb:Q9HCM9-2(isoform-parent)|entrezgene/locuslink:56658(identity)	-	crc64:B5B3B4CA37B82042	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:I7iIzRqPZAKdWQSe/IeGsW0qQcU559292	rogid:UfSn2+IVRxtGomVeDGdZpL7mz5I9606	intact-crc:09F603D0A7E32A26|rigid:s7Y0G+75Dh7YfGv3z3b4iFW+XHA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q08379	uniprotkb:P36149	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	intact:EBI-3567|uniprotkb:D6VXC9|ensemblfungi:YKR068C	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:bet3_yeast(display_long)|uniprotkb:YKR068C(locus name)|uniprotkb:BET3(gene name)|psi-mi:BET3(display_short)|uniprotkb:Transport protein particle 22 kDa subunit(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11527636|imex:IM-24995-554	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N|entrezgene/locuslink:2801(identity)	refseq:NP_012994.1|sgd:S000001776|dip:DIP-1710N|mint:P36149|ensemblfungi:YKR068C(gene)|ensemblfungi:YKR068C_mRNA(transcript)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0030008"(TRAPP complex)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0033106"(cis-Golgi network membrane)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:1990070"(TRAPPI protein complex)|go:"GO:1990071"(TRAPPII protein complex)|go:"GO:1990072"(TRAPPIII protein complex)|interpro:IPR007194("Transport protein particle (TRAPP) component, Bet3")|interpro:IPR016721(TRAPP I complex, Bet3)|interpro:IPR024096|rcsb pdb:3CUE|rcsb pdb:7KMT|reactome:R-SCE-204005|reactome:R-SCE-8876198|sgd:YKR068C(identity)	-	-	crc64:C802D8A3563DE82B	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2017/05/26	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	rogid:XN0vyDhpSkOFxu+sgthTqABoSxM559292	intact-crc:1E59197ED6B512B6|rigid:pgPBy01O66tFxjGKHTFMly7kMfQ	false	sufficient binding region:383-1002	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q15437	uniprotkb:P36125	intact:EBI-742673|uniprotkb:Q5W183|uniprotkb:Q9BS15|uniprotkb:Q9BSI2|uniprotkb:Q9H1D7|intact:EBI-1048165|uniprotkb:Q503A9|uniprotkb:D3DW33|ensembl:ENSP00000262544|ensembl:ENSP00000338844|ensembl:ENSP00000366685|ensembl:ENSP00000497473	intact:EBI-26378|uniprotkb:D6VX95|ensemblfungi:YKR030W	psi-mi:sc23b_human(display_long)|uniprotkb:SEC23-related protein B(gene name synonym)|uniprotkb:SEC23B(gene name)|psi-mi:SEC23B(display_short)	psi-mi:gmh1_yeast(display_long)|uniprotkb:YKR030W(locus name)|uniprotkb:GEA1-6 membrane-associated high-copy suppressor protein 1(gene name synonym)|uniprotkb:GMH1(gene name)|psi-mi:GMH1(display_short)|uniprotkb:MSG1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11527626|imex:IM-24995-553	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001166216.1|refseq:NP_006354.2|refseq:NP_116780.1|refseq:NP_116781.1|ensembl:ENSG00000101310(gene)|ensembl:ENST00000262544(transcript)|ensembl:ENST00000336714(transcript)|ensembl:ENST00000377465(transcript)|ensembl:ENST00000650089(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008270"(zinc ion binding)|go:"GO:0012505"(endomembrane system)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0090110"(COPII-coated vesicle cargo loading)|go:"GO:0070971"(endoplasmic reticulum exit site)|interpro:IPR006895(Zinc finger, Sec23/Sec24-type)|interpro:IPR006896(Sec23/Sec24 trunk region)|interpro:IPR006900(Sec23/Sec24 helical region)|interpro:IPR007123(Gelsolin region)|interpro:IPR012990(Sec23/Sec24 beta-sandwich)|interpro:IPR029006|interpro:IPR036174|interpro:IPR036175|interpro:IPR036180|interpro:IPR036465|interpro:IPR037364|interpro:IPR037550|mint:Q15437|refseq:XP_016883082.1|entrezgene/locuslink:10483(identity)	refseq:NP_012955.1|sgd:S000001738|mint:P36125|dip:DIP-2023N|ensemblfungi:YKR030W(gene)|ensemblfungi:YKR030W_mRNA(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030173"(integral component of Golgi membrane)|interpro:IPR007881(UNC-50)|sgd:YKR030W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:+3KZ/1jjziSgJRcr81Axquofkl49606	rogid:lmgeWk7CkMQRDAfkDOgwqC9rb/g559292	intact-crc:34EE1F0A941EB1D3|rigid:DPf4M4oTuC9pt++S4M+AuOcy+zA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q13422-7	uniprotkb:P36534	intact:EBI-11522367|ensembl:ENSP00000352123|ensembl:ENSP00000413025	intact:EBI-15595|uniprotkb:D6W3J5|uniprotkb:Q6B277|ensemblfungi:YPL173W	psi-mi:q13422-7(display_long)|uniprotkb:IKZF1(gene name)|psi-mi:IKZF1(display_short)|uniprotkb:IK1(gene name synonym)|uniprotkb:IKAROS(gene name synonym)|uniprotkb:Ikaros family zinc finger protein 1(gene name synonym)|uniprotkb:LYF1(gene name synonym)|uniprotkb:Lymphoid transcription factor LyF-1(gene name synonym)|uniprotkb:ZNFN1A1(gene name synonym)	psi-mi:rm40_yeast(display_long)|uniprotkb:YPL173W(locus name)|uniprotkb:MRPL40(gene name)|psi-mi:MRPL40(display_short)|uniprotkb:YmL40(gene name synonym)|uniprotkb:Mitochondrial large ribosomal subunit protein uL24m(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11527647|imex:IM-24995-555	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-745305(isoform-parent)|ensembl:ENSG00000185811(gene)|ensembl:ENST00000359197(transcript)|ensembl:ENST00000439701(transcript)|uniprotkb:Q13422-7(isoform-parent)|entrezgene/locuslink:10320(identity)	refseq:NP_015152.1|sgd:S000006094|ensemblfungi:YPL173W(gene)|ensemblfungi:YPL173W_mRNA(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0006412"(translation)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR003256(Ribosomal protein L24)|interpro:IPR005824(KOW)|interpro:IPR005825(Ribosomal protein L24/L26, conserved site)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR014722(Translation protein SH3-like, subgroup)|rcsb pdb:3J6B|rcsb pdb:5MRC|rcsb pdb:5MRE|rcsb pdb:5MRF|dip:DIP-7947N|mint:P36534|sgd:YPL173W(identity)	-	-	crc64:D5BB2B7AE13ECBF9	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:ou/ovXYoMneBNVp4pj38VxenfyY9606	rogid:NDbI5dslWtZzVGLPfKQTxT2o/bc559292	intact-crc:884A77FA20514485|rigid:P3hHvaBL/xXDnJCNMpzj6COuUyc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38128	uniprotkb:O14641	intact:EBI-17469|uniprotkb:D6VQH6|ensemblfungi:YBR182C	intact:EBI-740850|ensembl:ENSP00000005340|uniprotkb:Q53XM0|uniprotkb:D3DTN3	psi-mi:smp1_yeast(display_long)|uniprotkb:YBR1245(orf name)|uniprotkb:YBR182C(locus name)|uniprotkb:SMP1(gene name)|psi-mi:SMP1(display_short)	psi-mi:dvl2_human(display_long)|uniprotkb:DSH homolog 2(gene name synonym)|uniprotkb:DVL2(gene name)|psi-mi:DVL2(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11527758|imex:IM-24995-567	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009741.3|sgd:S000000386|interpro:IPR002100(Transcription factor, MADS-box)|ensemblfungi:YBR182C(gene)|ensemblfungi:YBR182C_mRNA(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|reactome:R-SCE-525793|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR033896|interpro:IPR036879|sgd:YBR182C(identity)	refseq:NP_004413.1|ensembl:ENSG00000004975(gene)|ensembl:ENST00000005340(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005109"(frizzled binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0007507"(heart development)|go:"GO:0016235"(aggresome)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044340"(canonical Wnt signaling pathway involved in regulation of cell proliferation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0150012"(positive regulation of neuron projection arborization)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008341(Dishevelled-2 region)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:O14641|rcsb pdb:2REY|rcsb pdb:3CBX|rcsb pdb:3CBY|rcsb pdb:3CBZ|rcsb pdb:3CC0|rcsb pdb:4WIP|rcsb pdb:5LNP|rcsb pdb:5SUY|rcsb pdb:5SUZ|rcsb pdb:6IW3|rcsb pdb:6JCK|reactome:R-HSA-201681|reactome:R-HSA-201688|reactome:R-HSA-2028269|reactome:R-HSA-4086400|reactome:R-HSA-4608870|reactome:R-HSA-4641258|reactome:R-HSA-4641262|reactome:R-HSA-5099900|reactome:R-HSA-5368598|reactome:R-HSA-5663220|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9673324|ensembl:ENSP00000005340|dip:DIP-34433N|entrezgene/locuslink:1856(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:+iBP5NzZkrXnslYfo1RDMrlTAIQ559292	rogid:2Vdc8oRnT4Mz/j+EXQXrL3AszOc9606	intact-crc:271888E6B6EC69BE|rigid:S5InodNAye0yjRMkLGG5XROWwz0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38128	uniprotkb:O00505	intact:EBI-17469|uniprotkb:D6VQH6|ensemblfungi:YBR182C	intact:EBI-358297|intact:EBI-28976892|ensembl:ENSP00000261667|uniprotkb:O00191|uniprotkb:O43195|uniprotkb:Q96AA7|uniprotkb:Q5JVM9|intact:EBI-742146|uniprotkb:Q8IYQ9	psi-mi:smp1_yeast(display_long)|uniprotkb:YBR1245(orf name)|uniprotkb:YBR182C(locus name)|uniprotkb:SMP1(gene name)|psi-mi:SMP1(display_short)	psi-mi:ima4_human(display_long)|uniprotkb:KPNA3(gene name)|psi-mi:KPNA3(display_short)|uniprotkb:QIP2(gene name synonym)|uniprotkb:Karyopherin subunit alpha-3(gene name synonym)|uniprotkb:SRP1-gamma(gene name synonym)|uniprotkb:Importin alpha Q2(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11527749|imex:IM-24995-566	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009741.3|sgd:S000000386|interpro:IPR002100(Transcription factor, MADS-box)|ensemblfungi:YBR182C(gene)|ensemblfungi:YBR182C_mRNA(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|reactome:R-SCE-525793|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR033896|interpro:IPR036879|sgd:YBR182C(identity)	ensembl:ENSG00000102753(gene)|ensembl:ENST00000261667(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0043657"(host cell)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0075732"(viral penetration into host nucleus)|interpro:IPR000225(Armadillo)|refseq:NP_002258.2|ensembl:ENSP00000261667|dip:DIP-27586N|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|mint:O00505|reactome:R-HSA-1169408|reactome:R-HSA-168276|entrezgene/locuslink:3839(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:+iBP5NzZkrXnslYfo1RDMrlTAIQ559292	rogid:kx/oTYWMYG7dhwJHvr1POLD6FTU9606	intact-crc:ABB99DE59774CC9F|rigid:vW49bMlKUJPjsYRy+VockKtA2Hg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38128	uniprotkb:Q08379	intact:EBI-17469|uniprotkb:D6VQH6|ensemblfungi:YBR182C	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	psi-mi:smp1_yeast(display_long)|uniprotkb:YBR1245(orf name)|uniprotkb:YBR182C(locus name)|uniprotkb:SMP1(gene name)|psi-mi:SMP1(display_short)	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11527738|imex:IM-24995-565	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009741.3|sgd:S000000386|interpro:IPR002100(Transcription factor, MADS-box)|ensemblfungi:YBR182C(gene)|ensemblfungi:YBR182C_mRNA(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|reactome:R-SCE-525793|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR033896|interpro:IPR036879|sgd:YBR182C(identity)	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N|entrezgene/locuslink:2801(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2017/05/26	rogid:+iBP5NzZkrXnslYfo1RDMrlTAIQ559292	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	intact-crc:F38FA6929F9D3D78|rigid:PmM+1BLaqJRaEfEEELirz9uDHbg	false	-	sufficient binding region:383-1002	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9NP64	uniprotkb:P37263	intact:EBI-746345|uniprotkb:Q6PKH4|uniprotkb:Q9NYG4|uniprotkb:Q9P0M8|uniprotkb:D3DPN4|ensembl:ENSP00000343557|ensembl:ENSP00000362819|uniprotkb:B4DY38	intact:EBI-21659|uniprotkb:D6VR87|ensemblfungi:YCR087C-A	psi-mi:no40_human(display_long)|uniprotkb:Zinc finger CCHC domain-containing protein 17(gene name synonym)|uniprotkb:Putative S1 RNA-binding domain protein(gene name synonym)|uniprotkb:Pnn-interacting nucleolar protein(gene name synonym)|uniprotkb:ZCCHC17(gene name)|psi-mi:ZCCHC17(display_short)|uniprotkb:HSPC243(orf name)|uniprotkb:HSPC251(orf name)|uniprotkb:LDC4(orf name)|uniprotkb:PS1D(gene name synonym)	psi-mi:yc16_yeast(display_long)|uniprotkb:YCRX16C(orf name)|uniprotkb:YCR087C-A(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11527693|imex:IM-24995-560	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001269495.1|refseq:NP_001269496.1|refseq:NP_001269497.1|refseq:NP_001269498.1|refseq:NP_001269499.1|refseq:NP_001269500.1|refseq:NP_001269501.1|refseq:NP_001269502.1|refseq:NP_001269503.1|refseq:XP_006710744.1|refseq:NP_057589.2|refseq:XP_011539869.1|ensembl:ENSG00000121766(gene)|ensembl:ENST00000344147(transcript)|ensembl:ENST00000373714(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0042802"(identical protein binding)|go:"GO:0043489"(RNA stabilization)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR003029(S1, RNA binding)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR022967|interpro:IPR037320|mint:Q9NP64|rcsb pdb:2CQO|entrezgene/locuslink:51538(identity)	refseq:NP_010011.1|sgd:S000007223|mint:P37263|dip:DIP-4536N|ensemblfungi:YCR087C-A(gene)|ensemblfungi:YCR087C-A_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR014898(Zinc finger, C2H2, LYAR-type)|interpro:IPR036236|interpro:IPR039999|sgd:YCR087C-A(identity)	-	-	crc64:B5B3B4CA37B82042	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:e71wAulRWX6cM59s3g8R42PWXeU9606	rogid:I7iIzRqPZAKdWQSe/IeGsW0qQcU559292	intact-crc:2E92173349193E31|rigid:Ml0Q/8mbm2fJgykAKfM9sgQUtFs	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38084	uniprotkb:Q8N6L0	intact:EBI-3414|uniprotkb:D6VQ67|ensemblfungi:YBR068C	intact:EBI-749265|uniprotkb:Q96MC3|ensembl:ENSP00000404220	psi-mi:bap2_yeast(display_long)|uniprotkb:Branched-chain amino-acid permease 2(gene name synonym)|uniprotkb:BAP2(gene name)|psi-mi:BAP2(display_short)|uniprotkb:YBR068C(locus name)|uniprotkb:YBR0629(orf name)	psi-mi:kash5_human(display_long)|uniprotkb:KASH5(gene name)|psi-mi:KASH5(display_short)|uniprotkb:CCDC155(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 155(gene name synonym)|uniprotkb:KASH domain-containing protein 5(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11527720|imex:IM-24995-563	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000000272|refseq:NP_009624.4|dip:DIP-4910N|mint:P38084|ensemblfungi:YBR068C(gene)|ensemblfungi:YBR068C_mRNA(transcript)|go:"GO:0003333"(amino acid transmembrane transport)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006865"(amino acid transport)|go:"GO:0015171"(amino acid transmembrane transporter activity)|go:"GO:0015192"(L-phenylalanine transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0055085"(transmembrane transport)|go:"GO:0098713"(leucine import across plasma membrane)|interpro:IPR004762(Amino acid permease, fungi)|interpro:IPR004840(Amino acid permease, conserved site)|interpro:IPR004841(Amino acid permease-associated region)|sgd:YBR068C(identity)	refseq:NP_653289.3|ensembl:ENSG00000161609(gene)|ensembl:ENST00000447857(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034397"(telomere localization)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051225"(spindle assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0090172"(microtubule cytoskeleton organization involved in homologous chromosome segregation)|go:"GO:0090220"(chromosome localization to nuclear envelope involved in homologous chromosome segregation)|go:"GO:0090619"(meiotic spindle pole)|interpro:IPR011992(EF-Hand type)|interpro:IPR028168|interpro:IPR028170|interpro:IPR039508|mint:Q8N6L0|rcsb pdb:6R2I|rcsb pdb:6WMF|entrezgene/locuslink:147872(identity)	-	crc64:B87FD6A7464E07F5	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:7Fw7+M5mBikZBztHE2tSDpvBi/M559292	rogid:Wl9L7AcvDHCZuKjYLn8QgGIbZTc9606	intact-crc:69ED421D4DD012D7|rigid:06KZtVfu+Zg0jAEL0cOjOPGPNAI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38011	uniprotkb:Q13829	intact:EBI-7405|uniprotkb:Q6LAA5|uniprotkb:D6VZT9|ensemblfungi:YMR116C	intact:EBI-2505861|uniprotkb:B7Z6M4|uniprotkb:Q5TZQ1|ensembl:ENSP00000226225	psi-mi:gblp_yeast(display_long)|uniprotkb:ASC1(gene name)|psi-mi:ASC1(display_short)|uniprotkb:CPC2(gene name synonym)|uniprotkb:Receptor of activated protein kinase C 1(gene name synonym)|uniprotkb:Receptor for activated C kinase(gene name synonym)|uniprotkb:Small ribosomal subunit protein RACK1(gene name synonym)|uniprotkb:YM9718.15C(orf name)|uniprotkb:YMR116C(locus name)	psi-mi:bacd2_human(display_long)|uniprotkb:BACURD2(gene name synonym)|uniprotkb:BTB/POZ domain-containing protein TNFAIP1(gene name synonym)|uniprotkb:Protein B12(gene name synonym)|uniprotkb:TNFAIP1(gene name)|psi-mi:TNFAIP1(display_short)|uniprotkb:EDP1(gene name synonym)|uniprotkb:Tumor necrosis factor, alpha-induced protein 1, endothelial(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11527711|imex:IM-24995-562	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013834.1|sgd:S000004722|mint:P38011|dip:DIP-6465N|ensemblfungi:YMR116C(gene)|ensemblfungi:YMR116C_mRNA(transcript)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001965"(G-protein alpha-subunit binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005092"(GDP-dissociation inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0008104"(protein localization)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0043022"(ribosome binding)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0072344"(rescue of stalled ribosome)|go:"GO:0080135"(regulation of cellular response to stress)|go:"GO:1902660"(negative regulation of glucose mediated signaling pathway)|go:"GO:2001125"(negative regulation of translational frameshifting)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|rcsb pdb:1TRJ|rcsb pdb:3FRX|rcsb pdb:3J6X|rcsb pdb:3J6Y|rcsb pdb:3J77|rcsb pdb:3J78|rcsb pdb:3RFG|rcsb pdb:3RFH|rcsb pdb:4U3M|rcsb pdb:4U3N|rcsb pdb:4U3U|rcsb pdb:4U4N|rcsb pdb:4U4O|rcsb pdb:4U4Q|rcsb pdb:4U4R|rcsb pdb:4U4U|rcsb pdb:4U4Y|rcsb pdb:4U4Z|rcsb pdb:4U50|rcsb pdb:4U51|rcsb pdb:4U52|rcsb pdb:4U53|rcsb pdb:4U55|rcsb pdb:4U56|rcsb pdb:4U6F|rcsb pdb:4V6I|rcsb pdb:4V7R|rcsb pdb:4V88|rcsb pdb:4V8Y|rcsb pdb:4V8Z|rcsb pdb:4V92|rcsb pdb:5DAT|rcsb pdb:5DC3|rcsb pdb:5DGE|rcsb pdb:5DGF|rcsb pdb:5DGV|rcsb pdb:5FCI|rcsb pdb:5FCJ|rcsb pdb:5I4L|rcsb pdb:5JUO|rcsb pdb:5JUP|rcsb pdb:5JUS|rcsb pdb:5JUT|rcsb pdb:5JUU|rcsb pdb:5LYB|rcsb pdb:5M1J|rcsb pdb:5MC6|rcsb pdb:5MEI|rcsb pdb:5NDG|rcsb pdb:5NDV|rcsb pdb:5NDW|rcsb pdb:5OBM|rcsb pdb:5ON6|rcsb pdb:5TBW|rcsb pdb:5TGA|rcsb pdb:5TGM|rcsb pdb:6FAI|rcsb pdb:6GQ1|rcsb pdb:6GQB|rcsb pdb:6GQV|rcsb pdb:6HHQ|rcsb pdb:6I7O|rcsb pdb:6Q8Y|rcsb pdb:6RBE|rcsb pdb:6S47|rcsb pdb:6SNT|rcsb pdb:6SV4|rcsb pdb:6T4Q|rcsb pdb:6T7I|rcsb pdb:6T7T|rcsb pdb:6T83|rcsb pdb:6TB3|rcsb pdb:6TNU|rcsb pdb:6WDR|rcsb pdb:6WOO|rcsb pdb:6XIQ|rcsb pdb:6XIR|rcsb pdb:6Z6J|rcsb pdb:6Z6K|rcsb pdb:6ZCE|rcsb pdb:6ZU9|rcsb pdb:6ZVI|rcsb pdb:7A1G|rcsb pdb:7NRC|rcsb pdb:7NRD|rcsb pdb:7B7D|sgd:YMR116C(identity)	refseq:NP_066960.1|ensembl:ENSG00000109079(gene)|ensembl:ENST00000226225(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006955"(immune response)|go:"GO:0016477"(cell migration)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030332"(cyclin binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0043149"(stress fiber assembly)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0051260"(protein homooligomerization)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR003131(Potassium channel, voltage dependent, Kv,  tetramerisation)|interpro:IPR011333(BTB/POZ fold)|mint:Q13829|reactome:R-HSA-9696264|reactome:R-HSA-9696270|entrezgene/locuslink:7126(identity)	-	crc64:B9A5D4959A3C54FB	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:T9ugPN58tGKmSOjRbv1bD1rznH8559292	rogid:8vM9HnNmkirDbJRETV/TeE8pONY9606	intact-crc:498334F012623C23|rigid:JG78HbwXtpeoM+ZQxJKJuB72en0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38011	uniprotkb:O43765	intact:EBI-7405|uniprotkb:Q6LAA5|uniprotkb:D6VZT9|ensemblfungi:YMR116C	intact:EBI-347996|ensembl:ENSP00000221566|ensembl:ENSP00000503397|ensembl:ENSP00000504495|uniprotkb:Q9BTZ9|intact:EBI-1045243|uniprotkb:Q6FIA9|uniprotkb:D6W610	psi-mi:gblp_yeast(display_long)|uniprotkb:ASC1(gene name)|psi-mi:ASC1(display_short)|uniprotkb:CPC2(gene name synonym)|uniprotkb:Receptor of activated protein kinase C 1(gene name synonym)|uniprotkb:Receptor for activated C kinase(gene name synonym)|uniprotkb:Small ribosomal subunit protein RACK1(gene name synonym)|uniprotkb:YM9718.15C(orf name)|uniprotkb:YMR116C(locus name)	psi-mi:sgta_human(display_long)|uniprotkb:SGTA(gene name)|psi-mi:SGTA(display_short)|uniprotkb:SGT(gene name synonym)|uniprotkb:Alpha-SGT(gene name synonym)|uniprotkb:Vpu-binding protein(gene name synonym)|uniprotkb:SGT1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11527702|imex:IM-24995-561	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013834.1|sgd:S000004722|mint:P38011|dip:DIP-6465N|ensemblfungi:YMR116C(gene)|ensemblfungi:YMR116C_mRNA(transcript)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001965"(G-protein alpha-subunit binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005092"(GDP-dissociation inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0008104"(protein localization)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0043022"(ribosome binding)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0072344"(rescue of stalled ribosome)|go:"GO:0080135"(regulation of cellular response to stress)|go:"GO:1902660"(negative regulation of glucose mediated signaling pathway)|go:"GO:2001125"(negative regulation of translational frameshifting)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|rcsb pdb:1TRJ|rcsb pdb:3FRX|rcsb pdb:3J6X|rcsb pdb:3J6Y|rcsb pdb:3J77|rcsb pdb:3J78|rcsb pdb:3RFG|rcsb pdb:3RFH|rcsb pdb:4U3M|rcsb pdb:4U3N|rcsb pdb:4U3U|rcsb pdb:4U4N|rcsb pdb:4U4O|rcsb pdb:4U4Q|rcsb pdb:4U4R|rcsb pdb:4U4U|rcsb pdb:4U4Y|rcsb pdb:4U4Z|rcsb pdb:4U50|rcsb pdb:4U51|rcsb pdb:4U52|rcsb pdb:4U53|rcsb pdb:4U55|rcsb pdb:4U56|rcsb pdb:4U6F|rcsb pdb:4V6I|rcsb pdb:4V7R|rcsb pdb:4V88|rcsb pdb:4V8Y|rcsb pdb:4V8Z|rcsb pdb:4V92|rcsb pdb:5DAT|rcsb pdb:5DC3|rcsb pdb:5DGE|rcsb pdb:5DGF|rcsb pdb:5DGV|rcsb pdb:5FCI|rcsb pdb:5FCJ|rcsb pdb:5I4L|rcsb pdb:5JUO|rcsb pdb:5JUP|rcsb pdb:5JUS|rcsb pdb:5JUT|rcsb pdb:5JUU|rcsb pdb:5LYB|rcsb pdb:5M1J|rcsb pdb:5MC6|rcsb pdb:5MEI|rcsb pdb:5NDG|rcsb pdb:5NDV|rcsb pdb:5NDW|rcsb pdb:5OBM|rcsb pdb:5ON6|rcsb pdb:5TBW|rcsb pdb:5TGA|rcsb pdb:5TGM|rcsb pdb:6FAI|rcsb pdb:6GQ1|rcsb pdb:6GQB|rcsb pdb:6GQV|rcsb pdb:6HHQ|rcsb pdb:6I7O|rcsb pdb:6Q8Y|rcsb pdb:6RBE|rcsb pdb:6S47|rcsb pdb:6SNT|rcsb pdb:6SV4|rcsb pdb:6T4Q|rcsb pdb:6T7I|rcsb pdb:6T7T|rcsb pdb:6T83|rcsb pdb:6TB3|rcsb pdb:6TNU|rcsb pdb:6WDR|rcsb pdb:6WOO|rcsb pdb:6XIQ|rcsb pdb:6XIR|rcsb pdb:6Z6J|rcsb pdb:6Z6K|rcsb pdb:6ZCE|rcsb pdb:6ZU9|rcsb pdb:6ZVI|rcsb pdb:7A1G|rcsb pdb:7NRC|rcsb pdb:7NRD|rcsb pdb:7B7D|sgd:YMR116C(identity)	rcsb pdb:4CPG|rcsb pdb:4GOD|rcsb pdb:4GOE|rcsb pdb:4GOF|reactome:R-HSA-9609523|rcsb pdb:2VYI|ensembl:ENSG00000104969(gene)|ensembl:ENST00000221566(transcript)|ensembl:ENST00000676943(transcript)|ensembl:ENST00000677149(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072380"(TRC complex)|go:"GO:0098850"(extrinsic component of synaptic vesicle membrane)|go:"GO:1903070"(negative regulation of ER-associated ubiquitin-dependent protein catabolic process)|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)|go:"GO:1903646"(positive regulation of chaperone-mediated protein folding)|go:"GO:1904288"(BAT3 complex binding)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR032374|mint:O43765|refseq:XP_011526480.1|refseq:NP_003012.1|entrezgene/locuslink:6449(identity)	-	crc64:B9A5D4959A3C54FB	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:T9ugPN58tGKmSOjRbv1bD1rznH8559292	rogid:r/Cyj4UJk/cS8QdrbjhTZMPCigI9606	intact-crc:B5125EF4E1CF6A35|rigid:JI7BWoHcftxx3AMPzyO2ZAnVCjU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38109	uniprotkb:Q14145	intact:EBI-21638|uniprotkb:D6VQD5|ensemblfungi:YBR139W	intact:EBI-751001|uniprotkb:B3KPD5|uniprotkb:Q8WTX1|uniprotkb:Q6LEP0|uniprotkb:Q9BPY9|intact:EBI-28976014|ensembl:ENSP00000171111|ensembl:ENSP00000377245	psi-mi:yby9_yeast(display_long)|uniprotkb:YBR1015(orf name)|uniprotkb:YBR139W(locus name)	psi-mi:keap1_human(display_long)|uniprotkb:Cytosolic inhibitor of Nrf2(gene name synonym)|uniprotkb:Kelch-like protein 19(gene name synonym)|uniprotkb:KEAP1(gene name)|psi-mi:KEAP1(display_short)|uniprotkb:INRF2(gene name synonym)|uniprotkb:KIAA0132(gene name synonym)|uniprotkb:KLHL19(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11527729|imex:IM-24995-564	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000000343|refseq:NP_009697.3|mint:P38109|dip:DIP-4923N|ensemblfungi:YBR139W(gene)|ensemblfungi:YBR139W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000328"(fungal-type vacuole lumen)|go:"GO:0004185"(serine-type carboxypeptidase activity)|go:"GO:0016236"(macroautophagy)|go:"GO:0017171"(serine hydrolase activity)|go:"GO:0031638"(zymogen activation)|go:"GO:0046938"(phytochelatin biosynthetic process)|interpro:IPR001563(Peptidase S10, serine carboxypeptidase)|interpro:IPR018202|interpro:IPR029058|interpro:IPR033124|sgd:YBR139W(identity)	refseq:NP_036421.2|refseq:NP_987096.1|ensembl:ENSP00000171111|ensembl:ENSP00000377245|refseq:XP_011526754.1|refseq:XP_005260230.1|refseq:XP_005260231.1|dip:DIP-42134N|ensembl:ENSG00000079999(gene)|ensembl:ENST00000171111(transcript)|ensembl:ENST00000393623(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0016234"(inclusion body)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030496"(midbody)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0034451"(centriolar satellite)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045604"(regulation of epidermal cell differentiation)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR017096(Kelch-like protein, gigaxonin)|interpro:IPR030563|mint:Q14145|rcsb pdb:1U6D|rcsb pdb:1ZGK|rcsb pdb:2FLU|rcsb pdb:3VNG|rcsb pdb:3VNH|rcsb pdb:3ZGC|rcsb pdb:3ZGD|rcsb pdb:4CXI|rcsb pdb:4CXJ|rcsb pdb:4CXT|rcsb pdb:4IFJ|rcsb pdb:4IFL|rcsb pdb:4IFN|rcsb pdb:4IN4|rcsb pdb:4IQK|rcsb pdb:4L7B|rcsb pdb:4L7C|rcsb pdb:4L7D|rcsb pdb:4N1B|rcsb pdb:4XMB|rcsb pdb:5DAD|rcsb pdb:5DAF|rcsb pdb:5F72|rcsb pdb:5GIT|rcsb pdb:5NLB|rcsb pdb:5WFL|rcsb pdb:5WFV|rcsb pdb:5WG1|rcsb pdb:5WHL|rcsb pdb:5WHO|rcsb pdb:5WIY|rcsb pdb:5X54|rcsb pdb:6FFM|rcsb pdb:6FMP|rcsb pdb:6FMQ|rcsb pdb:6HWS|rcsb pdb:6LRZ|rcsb pdb:6ROG|rcsb pdb:6SP1|rcsb pdb:6SP4|rcsb pdb:6T7V|rcsb pdb:6T7Z|rcsb pdb:6TG8|rcsb pdb:6TYM|rcsb pdb:6TYP|rcsb pdb:6UF0|rcsb pdb:6W66|rcsb pdb:6W67|rcsb pdb:6W68|rcsb pdb:6W69|rcsb pdb:6WCQ|rcsb pdb:6Z6A|rcsb pdb:7K28|rcsb pdb:7K29|rcsb pdb:7K2A|rcsb pdb:7K2B|rcsb pdb:7K2C|rcsb pdb:7K2D|rcsb pdb:7K2E|rcsb pdb:7K2F|rcsb pdb:7K2G|rcsb pdb:7K2H|rcsb pdb:7K2I|rcsb pdb:7K2J|rcsb pdb:7K2K|rcsb pdb:7K2L|rcsb pdb:7K2M|rcsb pdb:7K2N|rcsb pdb:7K2O|rcsb pdb:7K2P|rcsb pdb:7K2Q|rcsb pdb:7K2R|rcsb pdb:7K2S|reactome:R-HSA-5689880|reactome:R-HSA-8932339|reactome:R-HSA-8951664|reactome:R-HSA-983168|rcsb pdb:6V6Z|entrezgene/locuslink:9817(identity)	-	crc64:AAB2806C8EE2EDE1	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:x1bs6aRSmYGGBe4qebG37+9v4ek559292	rogid:3y/KqnUK+5nIyjhOEfkkthmP1OA9606	intact-crc:3D552A1902A6517B|rigid:H05m15ogeIMWg5dFsLakXE30J8g	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38151	uniprotkb:Q8N7W2-2	intact:EBI-12968|uniprotkb:D6VQM8|ensemblfungi:YBR233W	intact:EBI-10181188|ensembl:ENSP00000367868	psi-mi:pbp2_yeast(display_long)|uniprotkb:YBR1531(orf name)|uniprotkb:YBR233W(locus name)|uniprotkb:PBP2(gene name)|psi-mi:PBP2(display_short)	psi-mi:q8n7w2-2(display_long)|uniprotkb:C10orf30(gene name synonym)|uniprotkb:BEND7(gene name)|psi-mi:BEND7(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11527823|imex:IM-24995-574	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000000437|refseq:NP_009792.3|dip:DIP-4947N|ensemblfungi:YBR233W(gene)|ensemblfungi:YBR233W_mRNA(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0051252"(regulation of RNA metabolic process)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR036612|sgd:YBR233W(identity)	ensembl:ENSG00000165626(gene)|ensembl:ENST00000378605(transcript)|intact:EBI-743382(isoform-parent)|uniprotkb:Q8N7W2-2(isoform-parent)|entrezgene/locuslink:222389(identity)	-	crc64:638846509BCE1840	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:zcN9K+pivnit4l3Cl75wfk5F4VI559292	rogid:p6qrTn80hLyVU0W2Tvwn50Q4m5I9606	intact-crc:A034409A3AB007D4|rigid:mnpGnz+q9xWMm9vKv1ViKcntT3M	false	-	sufficient binding region:10-374	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P09012	uniprotkb:P38151	intact:EBI-607085|ensembl:ENSP00000243563	intact:EBI-12968|uniprotkb:D6VQM8|ensemblfungi:YBR233W	psi-mi:snrpa_human(display_long)|uniprotkb:SNRPA(gene name)|psi-mi:SNRPA(display_short)	psi-mi:pbp2_yeast(display_long)|uniprotkb:YBR1531(orf name)|uniprotkb:YBR233W(locus name)|uniprotkb:PBP2(gene name)|psi-mi:PBP2(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11527814|imex:IM-24995-573	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005685"(U1 snRNP)|go:"GO:0030619"(U1 snRNA binding)|ensembl:ENSG00000077312(gene)|go:"GO:0042802"(identical protein binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034407|interpro:IPR034409|interpro:IPR035979|mint:P09012|rcsb pdb:1AUD|ensembl:ENST00000243563(transcript)|rcsb pdb:1DRZ|rcsb pdb:1DZ5|rcsb pdb:1FHT|rcsb pdb:1M5K|rcsb pdb:1M5O|rcsb pdb:1M5P|rcsb pdb:1M5V|rcsb pdb:1NU4|rcsb pdb:1OIA|rcsb pdb:1SJ3|rcsb pdb:1SJ4|rcsb pdb:1SJF|rcsb pdb:1U6B|rcsb pdb:1URN|rcsb pdb:1VBX|rcsb pdb:1VBY|rcsb pdb:1VBZ|rcsb pdb:1VC0|rcsb pdb:1VC5|rcsb pdb:1VC6|rcsb pdb:1ZZN|rcsb pdb:2A3J|rcsb pdb:2NZ4|rcsb pdb:2OIH|rcsb pdb:2OJ3|rcsb pdb:2U1A|rcsb pdb:3BO2|rcsb pdb:3BO3|rcsb pdb:3BO4|rcsb pdb:3CUL|rcsb pdb:3CUN|rcsb pdb:3EGZ|rcsb pdb:3G8S|rcsb pdb:3G8T|rcsb pdb:3G96|rcsb pdb:3G9C|rcsb pdb:3HHN|rcsb pdb:3IIN|rcsb pdb:3IRW|rcsb pdb:3IWN|rcsb pdb:3K0J|rcsb pdb:3L3C|rcsb pdb:3MUM|rcsb pdb:3MUR|rcsb pdb:3MUT|rcsb pdb:3R1H|rcsb pdb:3R1L|rcsb pdb:3UCU|rcsb pdb:3UCZ|rcsb pdb:3UD3|rcsb pdb:3UD4|rcsb pdb:3MUV|rcsb pdb:3UTR|rcsb pdb:4C4W|rcsb pdb:4PR6|rcsb pdb:4PRF|rcsb pdb:4W90|rcsb pdb:4W92|rcsb pdb:3MXH|rcsb pdb:3P49|rcsb pdb:3PGW|rcsb pdb:4YB1|rcsb pdb:5DDO|rcsb pdb:5DDP|rcsb pdb:5DDQ|rcsb pdb:5DDR|rcsb pdb:5FJ4|rcsb pdb:6LAS|rcsb pdb:6LAU|rcsb pdb:6LAX|rcsb pdb:6LAZ|rcsb pdb:6QX9|rcsb pdb:6SQN|rcsb pdb:6SQQ|rcsb pdb:6SQT|rcsb pdb:6SQV|rcsb pdb:6SR7|rcsb pdb:6XH0|rcsb pdb:6XH1|rcsb pdb:6XH2|rcsb pdb:6XH3|rcsb pdb:7AEP|rcsb pdb:7B0Y|rcsb pdb:7D7V|rcsb pdb:7LHX|reactome:R-HSA-72163|refseq:NP_004587.1|dip:DIP-29407N|entrezgene/locuslink:6626(identity)	sgd:S000000437|refseq:NP_009792.3|dip:DIP-4947N|ensemblfungi:YBR233W(gene)|ensemblfungi:YBR233W_mRNA(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0051252"(regulation of RNA metabolic process)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR036612|sgd:YBR233W(identity)	-	-	crc64:638846509BCE1840	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:BJ9zdDzOPs9JYgU8lErj/maq0AY9606	rogid:zcN9K+pivnit4l3Cl75wfk5F4VI559292	intact-crc:32A04B86DD74E3C4|rigid:VvCgiZmrrXTe79IE0dPM+8vL6Iw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q08379	uniprotkb:P38151	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	intact:EBI-12968|uniprotkb:D6VQM8|ensemblfungi:YBR233W	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:pbp2_yeast(display_long)|uniprotkb:YBR1531(orf name)|uniprotkb:YBR233W(locus name)|uniprotkb:PBP2(gene name)|psi-mi:PBP2(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11527803|imex:IM-24995-572	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N|entrezgene/locuslink:2801(identity)	sgd:S000000437|refseq:NP_009792.3|dip:DIP-4947N|ensemblfungi:YBR233W(gene)|ensemblfungi:YBR233W_mRNA(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0051252"(regulation of RNA metabolic process)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR036612|sgd:YBR233W(identity)	-	-	crc64:638846509BCE1840	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2017/05/26	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	rogid:zcN9K+pivnit4l3Cl75wfk5F4VI559292	intact-crc:F87B3F723D0726A0|rigid:xQUBfMMwoTlpWhUucmKFmlQ9oAA	false	sufficient binding region:383-1002	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38128	uniprotkb:P14373	intact:EBI-17469|uniprotkb:D6VQH6|ensemblfungi:YBR182C	intact:EBI-719493|uniprotkb:A2BE15|uniprotkb:Q5RJA8|uniprotkb:Q5ST26|uniprotkb:Q6LA73|uniprotkb:Q6NXR9|uniprotkb:Q9BZY6|uniprotkb:Q9UJL3|ensembl:ENSP00000383555|ensembl:ENSP00000392787|ensembl:ENSP00000405229|ensembl:ENSP00000414793|ensembl:ENSP00000366404	psi-mi:smp1_yeast(display_long)|uniprotkb:YBR1245(orf name)|uniprotkb:YBR182C(locus name)|uniprotkb:SMP1(gene name)|psi-mi:SMP1(display_short)	psi-mi:tri27_human(display_long)|uniprotkb:TRIM27(gene name)|psi-mi:TRIM27(display_short)|uniprotkb:RNF76(gene name synonym)|uniprotkb:RFP(gene name synonym)|uniprotkb:Ret finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 27(gene name synonym)|uniprotkb:RING finger protein 76(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM27(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11527767|imex:IM-24995-568	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009741.3|sgd:S000000386|interpro:IPR002100(Transcription factor, MADS-box)|ensemblfungi:YBR182C(gene)|ensemblfungi:YBR182C_mRNA(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|reactome:R-SCE-525793|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR033896|interpro:IPR036879|sgd:YBR182C(identity)	refseq:NP_006501.1|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0090281"(negative regulation of calcium ion import)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR020457|interpro:IPR035791|interpro:IPR043136|mint:P14373|reactome:R-HSA-3232142|reactome:R-HSA-9635465|reactome:R-HSA-8948751|ensembl:ENSG00000204713(gene)|ensembl:ENSG00000215641(gene)|ensembl:ENSG00000229006(gene)|ensembl:ENSG00000234495(gene)|ensembl:ENSG00000237071(gene)|ensembl:ENST00000377199(transcript)|ensembl:ENST00000400720(transcript)|ensembl:ENST00000431123(transcript)|ensembl:ENST00000435528(transcript)|ensembl:ENST00000437160(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001650"(fibrillar center)|go:"GO:0002820"(negative regulation of adaptive immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|entrezgene/locuslink:5987(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:+iBP5NzZkrXnslYfo1RDMrlTAIQ559292	rogid:dsfH5OUghD8KSaTz1SFw9OYVTK49606	intact-crc:7C61D8E861D3A510|rigid:t/9+zqK7MrZBLRPnAemxMVxZ3lo	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9NRQ2	uniprotkb:P38128	intact:EBI-769257|uniprotkb:Q2TTR3|uniprotkb:Q658L3|uniprotkb:Q7Z505|uniprotkb:A8K2E9|uniprotkb:Q6ZR73|ensembl:ENSP00000347038|ensembl:ENSP00000399315|ensembl:ENSP00000419040	intact:EBI-17469|uniprotkb:D6VQH6|ensemblfungi:YBR182C	psi-mi:pls4_human(display_long)|uniprotkb:"Ca(2+)-dependent phospholipid scramblase 4"(gene name synonym)|uniprotkb:TRA1(gene name synonym)|uniprotkb:Cell growth-inhibiting gene 43 protein(gene name synonym)|uniprotkb:PLSCR4(gene name)|psi-mi:PLSCR4(display_short)|uniprotkb:GIG43(orf name)	psi-mi:smp1_yeast(display_long)|uniprotkb:YBR1245(orf name)|uniprotkb:YBR182C(locus name)|uniprotkb:SMP1(gene name)|psi-mi:SMP1(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11527785|imex:IM-24995-570	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_005247711.1|refseq:XP_005247712.1|refseq:NP_001121778.1|refseq:NP_001170775.1|refseq:NP_065086.2|refseq:NP_001121776.1|refseq:NP_001121777.1|refseq:XP_011511333.1|ensembl:ENSP00000347038|ensembl:ENST00000433593|ensembl:ENSP00000415605|ensembl:ENSP00000399315|ensembl:ENSP00000419040|ensembl:ENSG00000114698(gene)|ensembl:ENST00000354952(transcript)|ensembl:ENST00000446574(transcript)|ensembl:ENST00000493382(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017121"(plasma membrane phospholipid scrambling)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0017128"(phospholipid scramblase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0071222"(cellular response to lipopolysaccharide)|interpro:IPR005552(Scramblase)|rcsb pdb:3Q5U|entrezgene/locuslink:57088(identity)	refseq:NP_009741.3|sgd:S000000386|interpro:IPR002100(Transcription factor, MADS-box)|ensemblfungi:YBR182C(gene)|ensemblfungi:YBR182C_mRNA(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|reactome:R-SCE-525793|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR033896|interpro:IPR036879|sgd:YBR182C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:bqEhBoGZZebMZn4JWpg/X0qU49A9606	rogid:+iBP5NzZkrXnslYfo1RDMrlTAIQ559292	intact-crc:A3F94D3590D401B5|rigid:dnwTh4HBKpMmYhau8jiYq073Chc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38128	uniprotkb:P62714	intact:EBI-17469|uniprotkb:D6VQH6|ensemblfungi:YBR182C	intact:EBI-1044367|ensembl:ENSP00000221138|uniprotkb:P11082|uniprotkb:D3DSV4|uniprotkb:Q6FHK5	psi-mi:smp1_yeast(display_long)|uniprotkb:YBR1245(orf name)|uniprotkb:YBR182C(locus name)|uniprotkb:SMP1(gene name)|psi-mi:SMP1(display_short)	psi-mi:pp2ab_human(display_long)|uniprotkb:PPP2CB(gene name)|psi-mi:PPP2CB(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11527776|imex:IM-24995-569	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009741.3|sgd:S000000386|interpro:IPR002100(Transcription factor, MADS-box)|ensemblfungi:YBR182C(gene)|ensemblfungi:YBR182C_mRNA(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|reactome:R-SCE-525793|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR033896|interpro:IPR036879|sgd:YBR182C(identity)	refseq:NP_001009552.1|ensembl:ENSG00000104695(gene)|ensembl:ENST00000221138(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0010288"(response to lead ion)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046872"(metal ion binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|go:"GO:0006470"(protein dephosphorylation)|interpro:IPR029052|mint:P62714|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5675221|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-6804757|reactome:R-HSA-5673000|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|dip:DIP-42325N|entrezgene/locuslink:5516(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:+iBP5NzZkrXnslYfo1RDMrlTAIQ559292	rogid:ZWmB6it7rr0BS5sy38IxZ9QdR7U9606	intact-crc:03A75E89D56623B7|rigid:XK/kpDX0uyVVJjPhxen/wCS2Yyc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38148	uniprotkb:Q96ED9-2	intact:EBI-21161|uniprotkb:D6VQS2|ensemblfungi:YBR276C	intact:EBI-10961706|ensembl:ENSP00000264827	psi-mi:pps1_yeast(display_long)|uniprotkb:YBR2013(orf name)|uniprotkb:YBR276C(locus name)|uniprotkb:PPS1(gene name)|psi-mi:PPS1(display_short)	psi-mi:q96ed9-2(display_long)|uniprotkb:HOOK2(gene name)|psi-mi:HOOK2(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11527794|imex:IM-24995-571	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009835.3|sgd:S000000480|mint:P38148|dip:DIP-6546N|ensemblfungi:YBR276C(gene)|ensemblfungi:YBR276C_mRNA(transcript)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0008138"(protein tyrosine/serine/threonine phosphatase activity)|go:"GO:0033260"(nuclear DNA replication)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR000340(Protein-tyrosine phosphatase, dual specificity)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR020422|interpro:IPR029021|sgd:YBR276C(identity)	ensembl:ENSG00000095066(gene)|ensembl:ENST00000264827(transcript)|intact:EBI-743290(isoform-parent)|uniprotkb:Q96ED9-2(isoform-parent)|entrezgene/locuslink:29911(identity)	-	crc64:17840CF7256EF785	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:wB3u8/rxsyTrBOJKCyqomBBHGyE559292	rogid:aJZ/iDJpRk5dFL1NiouLuTjnOnc9606	intact-crc:52341F20984019F8|rigid:G1FQB0O5hccyrpSsh+7wLum1r9I	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38182	uniprotkb:Q12983	intact:EBI-2684|uniprotkb:D6VPS5|ensemblfungi:YBL078C	intact:EBI-749464|uniprotkb:O14620|uniprotkb:Q96GP0|intact:EBI-28978130|ensembl:ENSP00000357625	psi-mi:atg8_yeast(display_long)|uniprotkb:ATG8(gene name)|psi-mi:ATG8(display_short)|uniprotkb:APG8(gene name synonym)|uniprotkb:AUT7(gene name synonym)|uniprotkb:YBL078C(locus name)|uniprotkb:YBL0732(orf name)|uniprotkb:CVT5(gene name synonym)|uniprotkb:Autophagy-related ubiquitin-like modifier ATG8(gene name synonym)|uniprotkb:Cytoplasm to vacuole targeting protein 5(gene name synonym)	psi-mi:bnip3_human(display_long)|uniprotkb:BNIP3(gene name)|psi-mi:BNIP3(display_short)|uniprotkb:NIP3(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11527901|imex:IM-24995-582	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000000174|refseq:NP_009475.1|dip:DIP-1197N|mint:P38182|ensemblfungi:YBL078C(gene)|ensemblfungi:YBL078C_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006914"(autophagy)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0008429"(phosphatidylethanolamine binding)|go:"GO:0016236"(macroautophagy)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0031386"(protein tag)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0033110"(Cvt vesicle membrane)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0034629"|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|go:"GO:0061025"(membrane fusion)|go:"GO:0061709"(reticulophagy)|go:"GO:0071211"(protein targeting to vacuole involved in autophagy)|go:"GO:0120095"(vacuole-isolation membrane contact site)|go:"GO:1905153"(regulation of membrane invagination)|interpro:IPR004241("Light chain 3 (LC3)")|interpro:IPR029071|rcsb pdb:2KQ7|rcsb pdb:2KWC|rcsb pdb:2LI5|rcsb pdb:2ZPN|rcsb pdb:3RUI|rcsb pdb:3VH3|rcsb pdb:3VH4|rcsb pdb:3VXW|rcsb pdb:5YEC|rcsb pdb:6AAG|rcsb pdb:6WY6|rcsb pdb:7BRN|reactome:R-SCE-1632852|reactome:R-SCE-8854214|reactome:R-SCE-8934903|sgd:YBL078C(identity)	ensembl:ENSP00000357625|refseq:NP_004043.3|dip:DIP-34429N|ensembl:ENSG00000176171(gene)|ensembl:ENST00000368636(transcript)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006915"(apoptotic process)|go:"GO:0008219"(cell death)|go:"GO:0009617"(response to bacterium)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010637"(negative regulation of mitochondrial fusion)|go:"GO:0010659"(cardiac muscle cell apoptotic process)|go:"GO:0010666"(positive regulation of cardiac muscle cell apoptotic process)|go:"GO:0010917"(negative regulation of mitochondrial membrane potential)|go:"GO:0010940"(positive regulation of necrotic cell death)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030425"(dendrite)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0035694"(mitochondrial protein catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043067"(regulation of programmed cell death)|go:"GO:0043068"(positive regulation of programmed cell death)|go:"GO:0043243"(positive regulation of protein-containing complex disassembly)|go:"GO:0043653"(mitochondrial fragmentation involved in apoptotic process)|go:"GO:0045837"(negative regulation of membrane potential)|go:"GO:0046902"(regulation of mitochondrial membrane permeability)|go:"GO:0048102"(autophagic cell death)|go:"GO:0048678"(response to axon injury)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0050873"(brown fat cell differentiation)|go:"GO:0051020"(GTPase binding)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051561"(positive regulation of mitochondrial calcium ion concentration)|go:"GO:0051607"(defense response to virus)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071279"(cellular response to cobalt ion)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|go:"GO:0090649"(response to oxygen-glucose deprivation)|go:"GO:0097345"(mitochondrial outer membrane permeabilization)|go:"GO:0140507"(granzyme-mediated programmed cell death signaling pathway)|go:"GO:1901998"(toxin transport)|go:"GO:1902109"(negative regulation of mitochondrial membrane permeability involved in apoptotic process)|go:"GO:1903599"(positive regulation of autophagy of mitochondrion)|go:"GO:1903715"(regulation of aerobic respiration)|go:"GO:1990144"(intrinsic apoptotic signaling pathway in response to hypoxia)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|interpro:IPR010548(BNIP3)|mint:Q12983|rcsb pdb:2J5D|rcsb pdb:2KA1|rcsb pdb:2KA2|entrezgene/locuslink:664(identity)	-	crc64:1246CEFF5A038819	crc64:53967696EDA005E2	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2017/06/28	rogid:UlmpBW3JgdYFHLkZCQeJeb7DpK4559292	rogid:f+opYD7xO+AbYqLXXC5wh4ZJqIE9606	intact-crc:10D91DC496CDC0E8|rigid:E/j5dg5KUIp1NpkVYjNR0weuIE0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38182	uniprotkb:O60238	intact:EBI-2684|uniprotkb:D6VPS5|ensemblfungi:YBL078C	intact:EBI-849893|uniprotkb:Q5JW63|uniprotkb:Q8NF87|uniprotkb:B0AZS9|intact:EBI-28977676|ensembl:ENSP00000370003	psi-mi:atg8_yeast(display_long)|uniprotkb:ATG8(gene name)|psi-mi:ATG8(display_short)|uniprotkb:APG8(gene name synonym)|uniprotkb:AUT7(gene name synonym)|uniprotkb:YBL078C(locus name)|uniprotkb:YBL0732(orf name)|uniprotkb:CVT5(gene name synonym)|uniprotkb:Autophagy-related ubiquitin-like modifier ATG8(gene name synonym)|uniprotkb:Cytoplasm to vacuole targeting protein 5(gene name synonym)	psi-mi:bni3l_human(display_long)|uniprotkb:NIP3-like protein X(gene name synonym)|uniprotkb:BCL2/adenovirus E1B 19 kDa protein-interacting protein 3A(gene name synonym)|uniprotkb:Adenovirus E1B19K-binding protein B5(gene name synonym)|uniprotkb:BNIP3L(gene name)|psi-mi:BNIP3L(display_short)|uniprotkb:BNIP3A(gene name synonym)|uniprotkb:BNIP3H(gene name synonym)|uniprotkb:NIX(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11527892|imex:IM-24995-581	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000000174|refseq:NP_009475.1|dip:DIP-1197N|mint:P38182|ensemblfungi:YBL078C(gene)|ensemblfungi:YBL078C_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006914"(autophagy)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0008429"(phosphatidylethanolamine binding)|go:"GO:0016236"(macroautophagy)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0031386"(protein tag)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0033110"(Cvt vesicle membrane)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0034629"|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|go:"GO:0061025"(membrane fusion)|go:"GO:0061709"(reticulophagy)|go:"GO:0071211"(protein targeting to vacuole involved in autophagy)|go:"GO:0120095"(vacuole-isolation membrane contact site)|go:"GO:1905153"(regulation of membrane invagination)|interpro:IPR004241("Light chain 3 (LC3)")|interpro:IPR029071|rcsb pdb:2KQ7|rcsb pdb:2KWC|rcsb pdb:2LI5|rcsb pdb:2ZPN|rcsb pdb:3RUI|rcsb pdb:3VH3|rcsb pdb:3VH4|rcsb pdb:3VXW|rcsb pdb:5YEC|rcsb pdb:6AAG|rcsb pdb:6WY6|rcsb pdb:7BRN|reactome:R-SCE-1632852|reactome:R-SCE-8854214|reactome:R-SCE-8934903|sgd:YBL078C(identity)	refseq:NP_004322.1|ensembl:ENSP00000370003|ensembl:ENST00000518611|ensembl:ENSP00000429851|ensembl:ENST00000520409|ensembl:ENSP00000428597|ensembl:ENST00000523515|ensembl:ENSP00000429698|dip:DIP-35187N|refseq:NP_001317420.1|ensembl:ENSG00000104765(gene)|ensembl:ENST00000380629(transcript)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0010917"(negative regulation of mitochondrial membrane potential)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016607"(nuclear speck)|go:"GO:0031224"(intrinsic component of membrane)|go:"GO:0035694"(mitochondrial protein catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043067"(regulation of programmed cell death)|go:"GO:0051607"(defense response to virus)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0097345"(mitochondrial outer membrane permeabilization)|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1903214"(regulation of protein targeting to mitochondrion)|interpro:IPR010548(BNIP3)|mint:O60238|reactome:R-HSA-6803204|entrezgene/locuslink:665(identity)	-	crc64:1246CEFF5A038819	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:UlmpBW3JgdYFHLkZCQeJeb7DpK4559292	rogid:GPDlK/z2VOVzJspIhN8XNFPSVMo9606	intact-crc:A4B7BE0C2A823A5A|rigid:qQxn+uhb8vHnRhHxH9+ec9/R3nQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O43379	uniprotkb:P38182	intact:EBI-714790|uniprotkb:Q63HP9|uniprotkb:Q659D7|uniprotkb:Q8NBF7|uniprotkb:Q96AD9|intact:EBI-2563293|ensembl:ENSP00000270301	intact:EBI-2684|uniprotkb:D6VPS5|ensemblfungi:YBL078C	psi-mi:wdr62_human(display_long)|uniprotkb:WDR62(gene name)|psi-mi:WDR62(display_short)|uniprotkb:C19orf14(gene name synonym)	psi-mi:atg8_yeast(display_long)|uniprotkb:ATG8(gene name)|psi-mi:ATG8(display_short)|uniprotkb:APG8(gene name synonym)|uniprotkb:AUT7(gene name synonym)|uniprotkb:YBL078C(locus name)|uniprotkb:YBL0732(orf name)|uniprotkb:CVT5(gene name synonym)|uniprotkb:Autophagy-related ubiquitin-like modifier ATG8(gene name synonym)|uniprotkb:Cytoplasm to vacuole targeting protein 5(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11527881|imex:IM-24995-580	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007099"(centriole replication)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0022008"(neurogenesis)|go:"GO:0034451"(centriolar satellite)|interpro:IPR001680(WD40 repeat)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR024977|interpro:IPR036322|mint:O43379|go:"GO:0005813"(centrosome)|ensembl:ENSG00000075702(gene)|ensembl:ENST00000270301(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|refseq:NP_001077430.1|refseq:NP_775907.4|refseq:XP_016882154.1|dip:DIP-56792N|entrezgene/locuslink:284403(identity)	sgd:S000000174|refseq:NP_009475.1|dip:DIP-1197N|mint:P38182|ensemblfungi:YBL078C(gene)|ensemblfungi:YBL078C_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006914"(autophagy)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0008429"(phosphatidylethanolamine binding)|go:"GO:0016236"(macroautophagy)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0031386"(protein tag)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0033110"(Cvt vesicle membrane)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0034629"|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|go:"GO:0061025"(membrane fusion)|go:"GO:0061709"(reticulophagy)|go:"GO:0071211"(protein targeting to vacuole involved in autophagy)|go:"GO:0120095"(vacuole-isolation membrane contact site)|go:"GO:1905153"(regulation of membrane invagination)|interpro:IPR004241("Light chain 3 (LC3)")|interpro:IPR029071|rcsb pdb:2KQ7|rcsb pdb:2KWC|rcsb pdb:2LI5|rcsb pdb:2ZPN|rcsb pdb:3RUI|rcsb pdb:3VH3|rcsb pdb:3VH4|rcsb pdb:3VXW|rcsb pdb:5YEC|rcsb pdb:6AAG|rcsb pdb:6WY6|rcsb pdb:7BRN|reactome:R-SCE-1632852|reactome:R-SCE-8854214|reactome:R-SCE-8934903|sgd:YBL078C(identity)	-	-	crc64:1246CEFF5A038819	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:bKUivd80luQPFZHsU9mDdwyGwi89606	rogid:UlmpBW3JgdYFHLkZCQeJeb7DpK4559292	intact-crc:B49E1FFF26E573EC|rigid:Mf1TAEYS+GdwEh4qdc1A2+skDkQ	false	sufficient binding region:889-1518	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38151	uniprotkb:Q96PU8	intact:EBI-12968|uniprotkb:D6VQM8|ensemblfungi:YBR233W	intact:EBI-945792|uniprotkb:Q2I375|uniprotkb:Q5MJQ1|uniprotkb:Q969L9|uniprotkb:Q96EJ3|uniprotkb:Q96KA3|uniprotkb:Q96PU6|uniprotkb:Q96PU7|uniprotkb:Q9P0X6|uniprotkb:Q9P0X7|uniprotkb:Q9P0X8|uniprotkb:Q9P0X9|uniprotkb:Q9P0Y0|uniprotkb:Q9P0Y1|ensembl:ENSP00000355094	psi-mi:pbp2_yeast(display_long)|uniprotkb:YBR1531(orf name)|uniprotkb:YBR233W(locus name)|uniprotkb:PBP2(gene name)|psi-mi:PBP2(display_short)	psi-mi:qki_human(display_long)|uniprotkb:QKI(gene name)|psi-mi:QKI(display_short)|uniprotkb:HKQ(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11527834|imex:IM-24995-575	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000000437|refseq:NP_009792.3|dip:DIP-4947N|ensemblfungi:YBR233W(gene)|ensemblfungi:YBR233W_mRNA(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0051252"(regulation of RNA metabolic process)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR036612|sgd:YBR233W(identity)	refseq:NP_006766.1|refseq:NP_996735.1|refseq:NP_996736.1|refseq:NP_996737.1|refseq:NP_001288014.1|refseq:XP_011534561.1|ensembl:ENSG00000112531(gene)|ensembl:ENST00000361752(transcript)|go:"GO:0001570"(vasculogenesis)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0006417"(regulation of translation)|go:"GO:0007286"(spermatid development)|go:"GO:0008380"(RNA splicing)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0042552"(myelination)|go:"GO:0042692"(muscle cell differentiation)|go:"GO:0042759"(long-chain fatty acid biosynthetic process)|go:"GO:0045202"(synapse)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0051028"(mRNA transport)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR032367|interpro:IPR032377|interpro:IPR036612|mint:Q96PU8|rcsb pdb:4JVH|reactome:R-HSA-6802952|entrezgene/locuslink:9444(identity)	-	crc64:638846509BCE1840	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:zcN9K+pivnit4l3Cl75wfk5F4VI559292	rogid:7dcw5OyNAhQTE+yTch3qbSlZJdE9606	intact-crc:514FB82EE34BD004|rigid:LpPFQcO9qpi9sQJVGxaytAmOhKc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q15437	uniprotkb:P38166	intact:EBI-742673|uniprotkb:Q5W183|uniprotkb:Q9BS15|uniprotkb:Q9BSI2|uniprotkb:Q9H1D7|intact:EBI-1048165|uniprotkb:Q503A9|uniprotkb:D3DW33|ensembl:ENSP00000262544|ensembl:ENSP00000338844|ensembl:ENSP00000366685|ensembl:ENSP00000497473	intact:EBI-17046|uniprotkb:D6VPQ1|ensemblfungi:YBL102W	psi-mi:sc23b_human(display_long)|uniprotkb:SEC23-related protein B(gene name synonym)|uniprotkb:SEC23B(gene name)|psi-mi:SEC23B(display_short)	psi-mi:sft2_yeast(display_long)|uniprotkb:YBL0812(orf name)|uniprotkb:YBL102W(locus name)|uniprotkb:SFT2(gene name)|psi-mi:SFT2(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11527862|imex:IM-24995-578	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001166216.1|refseq:NP_006354.2|refseq:NP_116780.1|refseq:NP_116781.1|ensembl:ENSG00000101310(gene)|ensembl:ENST00000262544(transcript)|ensembl:ENST00000336714(transcript)|ensembl:ENST00000377465(transcript)|ensembl:ENST00000650089(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008270"(zinc ion binding)|go:"GO:0012505"(endomembrane system)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0090110"(COPII-coated vesicle cargo loading)|go:"GO:0070971"(endoplasmic reticulum exit site)|interpro:IPR006895(Zinc finger, Sec23/Sec24-type)|interpro:IPR006896(Sec23/Sec24 trunk region)|interpro:IPR006900(Sec23/Sec24 helical region)|interpro:IPR007123(Gelsolin region)|interpro:IPR012990(Sec23/Sec24 beta-sandwich)|interpro:IPR029006|interpro:IPR036174|interpro:IPR036175|interpro:IPR036180|interpro:IPR036465|interpro:IPR037364|interpro:IPR037550|mint:Q15437|refseq:XP_016883082.1|entrezgene/locuslink:10483(identity)	ensemblfungi:YBL102W(gene)|ensemblfungi:YBL102W_mRNA(transcript)|go:"GO:0000138"(Golgi trans cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005829"(cytosol)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|interpro:IPR007305(Got1-like protein)|interpro:IPR011691(SFT2-like)|refseq:NP_009448.1|sgd:S000000198|dip:DIP-1865N|mint:P38166|sgd:YBL102W(identity)	-	-	crc64:1BF971749814382C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:+3KZ/1jjziSgJRcr81Axquofkl49606	rogid:tGTSgSqEOsu/4dXIp31UzvtkyKs559292	intact-crc:EF80F2BD23B798B2|rigid:s/Px0A+1Hb5Mw2Fxv5DKdhsoRtA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9HCM9-2	uniprotkb:P38151	intact:EBI-11523450|ensembl:ENSP00000365847|ensembl:ENSP00000373095|ensembl:ENSP00000373097|ensembl:ENSP00000379797|ensembl:ENSP00000379800|ensembl:ENSP00000383486|ensembl:ENSP00000387445|ensembl:ENSP00000389198|ensembl:ENSP00000389852|ensembl:ENSP00000392130|ensembl:ENSP00000394353|ensembl:ENSP00000396986|ensembl:ENSP00000398956|ensembl:ENSP00000401071|ensembl:ENSP00000401184|ensembl:ENSP00000404340|ensembl:ENSP00000404904|ensembl:ENSP00000411582|ensembl:ENSP00000412743|ensembl:ENSP00000414525|ensembl:ENSP00000415259	intact:EBI-12968|uniprotkb:D6VQM8|ensemblfungi:YBR233W	psi-mi:q9hcm9-2(display_long)|uniprotkb:TRIM39(gene name)|psi-mi:TRIM39(display_short)|uniprotkb:RING finger protein 23(gene name synonym)|uniprotkb:RNF23(gene name synonym)|uniprotkb:TFP(gene name synonym)|uniprotkb:Testis-abundant finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 39(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM39(gene name synonym)|uniprotkb:TIM39beta(isoform synonym)	psi-mi:pbp2_yeast(display_long)|uniprotkb:YBR1531(orf name)|uniprotkb:YBR233W(locus name)|uniprotkb:PBP2(gene name)|psi-mi:PBP2(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11527852|imex:IM-24995-577	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-739510(isoform-parent)|ensembl:ENSG00000204599(gene)|ensembl:ENSG00000206495(gene)|ensembl:ENSG00000224994(gene)|ensembl:ENSG00000226437(gene)|ensembl:ENSG00000229929(gene)|ensembl:ENSG00000230308(gene)|ensembl:ENSG00000232839(gene)|ensembl:ENST00000376659(transcript)|ensembl:ENST00000383601(transcript)|ensembl:ENST00000383603(transcript)|ensembl:ENST00000396548(transcript)|ensembl:ENST00000396551(transcript)|ensembl:ENST00000400644(transcript)|ensembl:ENST00000414015(transcript)|ensembl:ENST00000419790(transcript)|ensembl:ENST00000430502(transcript)|ensembl:ENST00000431272(transcript)|ensembl:ENST00000433900(transcript)|ensembl:ENST00000438076(transcript)|ensembl:ENST00000438859(transcript)|ensembl:ENST00000440117(transcript)|ensembl:ENST00000443109(transcript)|ensembl:ENST00000446397(transcript)|ensembl:ENST00000449318(transcript)|ensembl:ENST00000450778(transcript)|ensembl:ENST00000451132(transcript)|ensembl:ENST00000452705(transcript)|ensembl:ENST00000458607(transcript)|uniprotkb:Q9HCM9-2(isoform-parent)|entrezgene/locuslink:56658(identity)	sgd:S000000437|refseq:NP_009792.3|dip:DIP-4947N|ensemblfungi:YBR233W(gene)|ensemblfungi:YBR233W_mRNA(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0051252"(regulation of RNA metabolic process)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR036612|sgd:YBR233W(identity)	-	-	crc64:638846509BCE1840	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:UfSn2+IVRxtGomVeDGdZpL7mz5I9606	rogid:zcN9K+pivnit4l3Cl75wfk5F4VI559292	intact-crc:48129B714B94706B|rigid:bVlRgMoN5MAv7jTlzTgLikI5FNw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9HAN9	uniprotkb:P38151	intact:EBI-3917542|uniprotkb:Q8TAE9|uniprotkb:Q9H6B6|uniprotkb:Q9H247|uniprotkb:B1AN63|ensembl:ENSP00000366410|ensembl:ENSP00000435134	intact:EBI-12968|uniprotkb:D6VQM8|ensemblfungi:YBR233W	psi-mi:nmna1_human(display_long)|uniprotkb:NMNAT1(gene name)|psi-mi:NMNAT1(display_short)|uniprotkb:NMNAT(gene name synonym)|uniprotkb:Nicotinate-nucleotide adenylyltransferase 1(gene name synonym)|uniprotkb:Nicotinamide-nucleotide adenylyltransferase 1(gene name synonym)	psi-mi:pbp2_yeast(display_long)|uniprotkb:YBR1531(orf name)|uniprotkb:YBR233W(locus name)|uniprotkb:PBP2(gene name)|psi-mi:PBP2(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11527843|imex:IM-24995-576	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001284707.1|refseq:NP_073624.2|ensembl:ENSG00000173614(gene)|ensembl:ENST00000377205(transcript)|ensembl:ENST00000462686(transcript)|go:"GO:0000309"(nicotinamide-nucleotide adenylyltransferase activity)|go:"GO:0004515"(nicotinate-nucleotide adenylyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0009165"(nucleotide biosynthetic process)|go:"GO:0009435"(NAD biosynthetic process)|go:"GO:0009611"(response to wounding)|go:"GO:0016604"(nuclear body)|go:"GO:0042802"(identical protein binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:1902511"(negative regulation of apoptotic DNA fragmentation)|go:"GO:1990966"(ATP generation from poly-ADP-D-ribose)|interpro:IPR004821(Cytidyltransferase-related)|interpro:IPR005248(Probable nicotinate-nucleotide adenylyltransferase)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|mint:Q9HAN9|rcsb pdb:1GZU|rcsb pdb:1KKU|rcsb pdb:1KQN|rcsb pdb:1KQO|rcsb pdb:1KR2|reactome:R-HSA-196807|refseq:XP_016857596.1|dip:DIP-60881N|entrezgene/locuslink:64802(identity)	sgd:S000000437|refseq:NP_009792.3|dip:DIP-4947N|ensemblfungi:YBR233W(gene)|ensemblfungi:YBR233W_mRNA(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0051252"(regulation of RNA metabolic process)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR036612|sgd:YBR233W(identity)	-	-	crc64:638846509BCE1840	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:KwV9lz04z3ptlVpKu3b534Yekpc9606	rogid:zcN9K+pivnit4l3Cl75wfk5F4VI559292	intact-crc:E9B08532BC7B5373|rigid:ueKN62aID4CjKR81IgQzdYM3Tk8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O43765	uniprotkb:P38168	intact:EBI-347996|ensembl:ENSP00000221566|ensembl:ENSP00000503397|ensembl:ENSP00000504495|uniprotkb:Q9BTZ9|intact:EBI-1045243|uniprotkb:Q6FIA9|uniprotkb:D6W610	intact:EBI-21355|ensemblfungi:YBL100C	psi-mi:sgta_human(display_long)|uniprotkb:SGTA(gene name)|psi-mi:SGTA(display_short)|uniprotkb:SGT(gene name synonym)|uniprotkb:Alpha-SGT(gene name synonym)|uniprotkb:Vpu-binding protein(gene name synonym)|uniprotkb:SGT1(gene name synonym)	psi-mi:ybk0_yeast(display_long)|uniprotkb:YBL0826(orf name)|uniprotkb:YBL100C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11527872|imex:IM-24995-579	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:4CPG|rcsb pdb:4GOD|rcsb pdb:4GOE|rcsb pdb:4GOF|reactome:R-HSA-9609523|rcsb pdb:2VYI|ensembl:ENSG00000104969(gene)|ensembl:ENST00000221566(transcript)|ensembl:ENST00000676943(transcript)|ensembl:ENST00000677149(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072380"(TRC complex)|go:"GO:0098850"(extrinsic component of synaptic vesicle membrane)|go:"GO:1903070"(negative regulation of ER-associated ubiquitin-dependent protein catabolic process)|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)|go:"GO:1903646"(positive regulation of chaperone-mediated protein folding)|go:"GO:1904288"(BAT3 complex binding)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR032374|mint:O43765|refseq:XP_011526480.1|refseq:NP_003012.1|entrezgene/locuslink:6449(identity)	sgd:S000000196|dip:DIP-5675N|ensemblfungi:YBL100C(gene)|ensemblfungi:YBL100C_mRNA(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|sgd:YBL100C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:r/Cyj4UJk/cS8QdrbjhTZMPCigI9606	rogid:gPuMXsZP2fRnDh4HhKc6uX1tT8M559292	intact-crc:35EAC6A6E4A0DE9C|rigid:3OnFZnXxD10R/tRtUYSZvlE7F5g	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8N6L0	uniprotkb:P38206	intact:EBI-749265|uniprotkb:Q96MC3|ensembl:ENSP00000404220	intact:EBI-15028|uniprotkb:Q05814|uniprotkb:D6VPY0|ensemblfungi:YBL020W	psi-mi:kash5_human(display_long)|uniprotkb:KASH5(gene name)|psi-mi:KASH5(display_short)|uniprotkb:CCDC155(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 155(gene name synonym)|uniprotkb:KASH domain-containing protein 5(gene name synonym)	psi-mi:rft1_yeast(display_long)|uniprotkb:RFT1(gene name)|psi-mi:RFT1(display_short)|uniprotkb:YBL020W(locus name)|uniprotkb:YBL0442(orf name)|uniprotkb:Requiring fifty-three protein 1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11527956|imex:IM-24995-588	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_653289.3|ensembl:ENSG00000161609(gene)|ensembl:ENST00000447857(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034397"(telomere localization)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051225"(spindle assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0090172"(microtubule cytoskeleton organization involved in homologous chromosome segregation)|go:"GO:0090220"(chromosome localization to nuclear envelope involved in homologous chromosome segregation)|go:"GO:0090619"(meiotic spindle pole)|interpro:IPR011992(EF-Hand type)|interpro:IPR028168|interpro:IPR028170|interpro:IPR039508|mint:Q8N6L0|rcsb pdb:6R2I|rcsb pdb:6WMF|entrezgene/locuslink:147872(identity)	refseq:NP_009533.1|sgd:S000000116|ensemblfungi:YBL020W(gene)|ensemblfungi:YBL020W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006488"(dolichol-linked oligosaccharide biosynthetic process)|go:"GO:0008643"(carbohydrate transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034202"(glycolipid floppase activity)|go:"GO:0034203"(glycolipid translocation)|interpro:IPR007594(RFT1)|dip:DIP-3885N|mint:P38206|sgd:YBL020W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Wl9L7AcvDHCZuKjYLn8QgGIbZTc9606	rogid:nBfsGoVh81NwPryblR48jOVVQsU559292	intact-crc:FFACCE06F6C0CCC9|rigid:+mKcNMiv2h/xD/MRZ7N4T/Iqe50	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8IV61	uniprotkb:P38206	intact:EBI-1047876|uniprotkb:O94931|uniprotkb:Q53SD7|uniprotkb:D6W583|ensembl:ENSP00000384192|ensembl:ENSP00000385886	intact:EBI-15028|uniprotkb:Q05814|uniprotkb:D6VPY0|ensemblfungi:YBL020W	psi-mi:grp3_human(display_long)|uniprotkb:Calcium and DAG-regulated guanine nucleotide exchange factor III(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor for Rap1(gene name synonym)|uniprotkb:RASGRP3(gene name)|psi-mi:RASGRP3(display_short)|uniprotkb:GRP3(gene name synonym)|uniprotkb:KIAA0846(gene name synonym)	psi-mi:rft1_yeast(display_long)|uniprotkb:RFT1(gene name)|psi-mi:RFT1(display_short)|uniprotkb:YBL020W(locus name)|uniprotkb:YBL0442(orf name)|uniprotkb:Requiring fifty-three protein 1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11527947|imex:IM-24995-587	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001132960.1|refseq:NP_056191.1|refseq:NP_733772.1|refseq:XP_011531048.1|refseq:XP_011531049.1|refseq:XP_016859248.1|refseq:XP_016859249.1|refseq:XP_016859250.1|refseq:XP_016859251.1|refseq:XP_016859252.1|refseq:XP_011531050.2|ensembl:ENSG00000152689(gene)|ensembl:ENST00000402538(transcript)|ensembl:ENST00000403687(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0019900"(kinase binding)|go:"GO:0019992"(diacylglycerol binding)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR000651(Guanine nucleotide exchange factor for Ras-like GTPases, N-terminal)|interpro:IPR001895(Guanine-nucleotide dissociation stimulator CDC25)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008937(Ras guanine nucleotide exchange factor)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR020454|interpro:IPR023578|interpro:IPR029645|interpro:IPR036964|reactome:R-HSA-1169092|reactome:R-HSA-5673001|refseq:XP_005264303.1|entrezgene/locuslink:25780(identity)	refseq:NP_009533.1|sgd:S000000116|ensemblfungi:YBL020W(gene)|ensemblfungi:YBL020W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006488"(dolichol-linked oligosaccharide biosynthetic process)|go:"GO:0008643"(carbohydrate transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034202"(glycolipid floppase activity)|go:"GO:0034203"(glycolipid translocation)|interpro:IPR007594(RFT1)|dip:DIP-3885N|mint:P38206|sgd:YBL020W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:yO4CIzGZmGYS124YcNmFKQh7+bo9606	rogid:nBfsGoVh81NwPryblR48jOVVQsU559292	intact-crc:55A54393A754E0B5|rigid:ni8QLeHB1RRrD7d0Bqy0qtRmISk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38203	uniprotkb:P14373	intact:EBI-180|ensemblfungi:YBL026W|uniprotkb:D6VPX4	intact:EBI-719493|uniprotkb:A2BE15|uniprotkb:Q5RJA8|uniprotkb:Q5ST26|uniprotkb:Q6LA73|uniprotkb:Q6NXR9|uniprotkb:Q9BZY6|uniprotkb:Q9UJL3|ensembl:ENSP00000383555|ensembl:ENSP00000392787|ensembl:ENSP00000405229|ensembl:ENSP00000414793|ensembl:ENSP00000366404	psi-mi:lsm2_yeast(display_long)|uniprotkb:LSM2(gene name)|psi-mi:LSM2(display_short)|uniprotkb:Small nuclear ribonucleoprotein D homolog SNP3(gene name synonym)|uniprotkb:SMX5(gene name synonym)|uniprotkb:SNP3(gene name synonym)|uniprotkb:YBL0425(orf name)|uniprotkb:YBL026W(locus name)	psi-mi:tri27_human(display_long)|uniprotkb:TRIM27(gene name)|psi-mi:TRIM27(display_short)|uniprotkb:RNF76(gene name synonym)|uniprotkb:RFP(gene name synonym)|uniprotkb:Ret finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 27(gene name synonym)|uniprotkb:RING finger protein 76(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM27(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11527938|imex:IM-24995-586	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009527.1|sgd:S000000122|go:"GO:0005688"(U6 snRNP)|go:"GO:0005730"(nucleolus)|go:"GO:0005732"("sno(s)RNA-containing ribonucleoprotein complex")|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0008033"(tRNA processing)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990726"(Lsm1-7-Pat1 complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR016654(U6 snRNA-associated Sm-like protein LSm2)|rcsb pdb:3JCM|rcsb pdb:4C8Q|rcsb pdb:4C92|rcsb pdb:4M75|rcsb pdb:4M77|ensemblfungi:YBL026W(gene)|ensemblfungi:YBL026W_mRNA(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|mint:P38203|dip:DIP-794N|rcsb pdb:4M78|rcsb pdb:4M7A|rcsb pdb:4M7D|rcsb pdb:4N0A|rcsb pdb:5GAN|rcsb pdb:5NRL|rcsb pdb:5VSU|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:6ASO|reactome:R-SCE-430039|sgd:YBL026W(identity)	refseq:NP_006501.1|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0090281"(negative regulation of calcium ion import)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR020457|interpro:IPR035791|interpro:IPR043136|mint:P14373|reactome:R-HSA-3232142|reactome:R-HSA-9635465|reactome:R-HSA-8948751|ensembl:ENSG00000204713(gene)|ensembl:ENSG00000215641(gene)|ensembl:ENSG00000229006(gene)|ensembl:ENSG00000234495(gene)|ensembl:ENSG00000237071(gene)|ensembl:ENST00000377199(transcript)|ensembl:ENST00000400720(transcript)|ensembl:ENST00000431123(transcript)|ensembl:ENST00000435528(transcript)|ensembl:ENST00000437160(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001650"(fibrillar center)|go:"GO:0002820"(negative regulation of adaptive immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|entrezgene/locuslink:5987(identity)	-	crc64:C23856268CEE92E2	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:3E5c7Mzg433awFPmamamsKjtJmY559292	rogid:dsfH5OUghD8KSaTz1SFw9OYVTK49606	intact-crc:6F6C9102700136CA|rigid:hXyimIo/ILQQZTcsfdF11Q+LFPc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UH92-3	uniprotkb:P38182	intact:EBI-8852072|ensembl:ENSP00000416627	intact:EBI-2684|uniprotkb:D6VPS5|ensemblfungi:YBL078C	psi-mi:q9uh92-3(display_long)|uniprotkb:MLX(gene name)|psi-mi:MLX(display_short)|uniprotkb:BHLHD13(gene name synonym)|uniprotkb:TCFL4(gene name synonym)|uniprotkb:Class D basic helix-loop-helix protein 13(gene name synonym)|uniprotkb:Max-like bHLHZip protein(gene name synonym)|uniprotkb:Protein BigMax(gene name synonym)|uniprotkb:Transcription factor-like protein 4(gene name synonym)	psi-mi:atg8_yeast(display_long)|uniprotkb:ATG8(gene name)|psi-mi:ATG8(display_short)|uniprotkb:APG8(gene name synonym)|uniprotkb:AUT7(gene name synonym)|uniprotkb:YBL078C(locus name)|uniprotkb:YBL0732(orf name)|uniprotkb:CVT5(gene name synonym)|uniprotkb:Autophagy-related ubiquitin-like modifier ATG8(gene name synonym)|uniprotkb:Cytoplasm to vacuole targeting protein 5(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11527929|imex:IM-24995-585	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000108788(gene)|ensembl:ENST00000435881(transcript)|intact:EBI-741109(isoform-parent)|uniprotkb:Q9UH92-3(isoform-parent)|entrezgene/locuslink:6945(identity)	sgd:S000000174|refseq:NP_009475.1|dip:DIP-1197N|mint:P38182|ensemblfungi:YBL078C(gene)|ensemblfungi:YBL078C_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006914"(autophagy)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0008429"(phosphatidylethanolamine binding)|go:"GO:0016236"(macroautophagy)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0031386"(protein tag)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0033110"(Cvt vesicle membrane)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0034629"|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|go:"GO:0061025"(membrane fusion)|go:"GO:0061709"(reticulophagy)|go:"GO:0071211"(protein targeting to vacuole involved in autophagy)|go:"GO:0120095"(vacuole-isolation membrane contact site)|go:"GO:1905153"(regulation of membrane invagination)|interpro:IPR004241("Light chain 3 (LC3)")|interpro:IPR029071|rcsb pdb:2KQ7|rcsb pdb:2KWC|rcsb pdb:2LI5|rcsb pdb:2ZPN|rcsb pdb:3RUI|rcsb pdb:3VH3|rcsb pdb:3VH4|rcsb pdb:3VXW|rcsb pdb:5YEC|rcsb pdb:6AAG|rcsb pdb:6WY6|rcsb pdb:7BRN|reactome:R-SCE-1632852|reactome:R-SCE-8854214|reactome:R-SCE-8934903|sgd:YBL078C(identity)	-	-	crc64:1246CEFF5A038819	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:M3gABDaYvwenMrLrp6Tbpl6ZU909606	rogid:UlmpBW3JgdYFHLkZCQeJeb7DpK4559292	intact-crc:91B6E8661165F7FB|rigid:EWuh8wGIWzo/TY2TXJgjg7rbuHc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96GX9	uniprotkb:P38182	intact:EBI-359248|ensembl:ENSP00000379133|intact:EBI-2848621|uniprotkb:Q6PJX6|uniprotkb:Q8WVU2|uniprotkb:Q96HK2|uniprotkb:Q9Y318|uniprotkb:A8K9D3	intact:EBI-2684|uniprotkb:D6VPS5|ensemblfungi:YBL078C	psi-mi:mtnb_human(display_long)|uniprotkb:APIP(gene name)|psi-mi:APIP(display_short)|uniprotkb:CGI-29(orf name)|uniprotkb:APAF1-interacting protein(gene name synonym)	psi-mi:atg8_yeast(display_long)|uniprotkb:ATG8(gene name)|psi-mi:ATG8(display_short)|uniprotkb:APG8(gene name synonym)|uniprotkb:AUT7(gene name synonym)|uniprotkb:YBL078C(locus name)|uniprotkb:YBL0732(orf name)|uniprotkb:CVT5(gene name synonym)|uniprotkb:Autophagy-related ubiquitin-like modifier ATG8(gene name synonym)|uniprotkb:Cytoplasm to vacuole targeting protein 5(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11527919|imex:IM-24995-584	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000149089(gene)|ensembl:ENST00000395787(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019284"(L-methionine salvage from S-adenosylmethionine)|go:"GO:0019509"(L-methionine salvage from methylthioadenosine)|refseq:NP_057041.2|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0046570"(methylthioribulose 1-phosphate dehydratase activity)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0070269"(pyroptosis)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|interpro:IPR001303(Class II aldolase/adducin, N-terminal)|interpro:IPR017714(Methylthioribulose-1-phosphate dehydratase)|interpro:IPR027514|interpro:IPR036409|rcsb pdb:4M6R|reactome:R-HSA-111458|reactome:R-HSA-1237112|reactome:R-HSA-9627069|entrezgene/locuslink:51074(identity)	sgd:S000000174|refseq:NP_009475.1|dip:DIP-1197N|mint:P38182|ensemblfungi:YBL078C(gene)|ensemblfungi:YBL078C_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006914"(autophagy)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0008429"(phosphatidylethanolamine binding)|go:"GO:0016236"(macroautophagy)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0031386"(protein tag)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0033110"(Cvt vesicle membrane)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0034629"|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|go:"GO:0061025"(membrane fusion)|go:"GO:0061709"(reticulophagy)|go:"GO:0071211"(protein targeting to vacuole involved in autophagy)|go:"GO:0120095"(vacuole-isolation membrane contact site)|go:"GO:1905153"(regulation of membrane invagination)|interpro:IPR004241("Light chain 3 (LC3)")|interpro:IPR029071|rcsb pdb:2KQ7|rcsb pdb:2KWC|rcsb pdb:2LI5|rcsb pdb:2ZPN|rcsb pdb:3RUI|rcsb pdb:3VH3|rcsb pdb:3VH4|rcsb pdb:3VXW|rcsb pdb:5YEC|rcsb pdb:6AAG|rcsb pdb:6WY6|rcsb pdb:7BRN|reactome:R-SCE-1632852|reactome:R-SCE-8854214|reactome:R-SCE-8934903|sgd:YBL078C(identity)	-	-	crc64:1246CEFF5A038819	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:k+IcLEB6jPgZW0Zl597PZyGbHH49606	rogid:UlmpBW3JgdYFHLkZCQeJeb7DpK4559292	intact-crc:32D8F83B7380D13A|rigid:wgy+lOhNd+Qn5eTzjT8SW6Hbl6g	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38182	uniprotkb:Q92609	intact:EBI-2684|uniprotkb:D6VPS5|ensemblfungi:YBL078C	intact:EBI-742381|uniprotkb:A6NP25|intact:EBI-28978959|ensembl:ENSP00000253692|ensembl:ENSP00000398127|uniprotkb:C9JP52	psi-mi:atg8_yeast(display_long)|uniprotkb:ATG8(gene name)|psi-mi:ATG8(display_short)|uniprotkb:APG8(gene name synonym)|uniprotkb:AUT7(gene name synonym)|uniprotkb:YBL078C(locus name)|uniprotkb:YBL0732(orf name)|uniprotkb:CVT5(gene name synonym)|uniprotkb:Autophagy-related ubiquitin-like modifier ATG8(gene name synonym)|uniprotkb:Cytoplasm to vacuole targeting protein 5(gene name synonym)	psi-mi:tbcd5_human(display_long)|uniprotkb:TBC1D5(gene name)|psi-mi:TBC1D5(display_short)|uniprotkb:KIAA0210(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11527910|imex:IM-24995-583	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000000174|refseq:NP_009475.1|dip:DIP-1197N|mint:P38182|ensemblfungi:YBL078C(gene)|ensemblfungi:YBL078C_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006914"(autophagy)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0008429"(phosphatidylethanolamine binding)|go:"GO:0016236"(macroautophagy)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0031386"(protein tag)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0033110"(Cvt vesicle membrane)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0034629"|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|go:"GO:0061025"(membrane fusion)|go:"GO:0061709"(reticulophagy)|go:"GO:0071211"(protein targeting to vacuole involved in autophagy)|go:"GO:0120095"(vacuole-isolation membrane contact site)|go:"GO:1905153"(regulation of membrane invagination)|interpro:IPR004241("Light chain 3 (LC3)")|interpro:IPR029071|rcsb pdb:2KQ7|rcsb pdb:2KWC|rcsb pdb:2LI5|rcsb pdb:2ZPN|rcsb pdb:3RUI|rcsb pdb:3VH3|rcsb pdb:3VH4|rcsb pdb:3VXW|rcsb pdb:5YEC|rcsb pdb:6AAG|rcsb pdb:6WY6|rcsb pdb:7BRN|reactome:R-SCE-1632852|reactome:R-SCE-8854214|reactome:R-SCE-8934903|sgd:YBL078C(identity)	ensembl:ENSP00000253692|ensembl:ENSP00000398127|ensembl:ENSP00000402935|ensembl:ENST00000446818|refseq:NP_055559.1|refseq:XP_011532586.1|refseq:XP_011532583.1|refseq:XP_011532585.1|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005776"(autophagosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006914"(autophagy)|go:"GO:0010008"(endosome membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0030904"(retromer complex)|go:"GO:0035612"(AP-2 adaptor complex binding)|ensembl:ENSG00000131374(gene)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042594"(response to starvation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:1905394"(retromer complex binding)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR035969|mint:Q92609|rcsb pdb:5GTU|ensembl:ENST00000253692(transcript)|ensembl:ENST00000429383(transcript)|go:"GO:0002092"(positive regulation of receptor internalization)|refseq:NP_001127853.1|refseq:XP_006713493.1|refseq:XP_016863041.1|refseq:XP_016863042.1|refseq:XP_016863043.1|refseq:XP_016863044.1|refseq:XP_016863045.1|refseq:XP_016863046.1|entrezgene/locuslink:9779(identity)	-	crc64:1246CEFF5A038819	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:UlmpBW3JgdYFHLkZCQeJeb7DpK4559292	rogid:GZ7WP4suMiSPSAJK0TZWQMQZxzU9606	intact-crc:C135CFD924C1C73B|rigid:7v+nlQJThCowWc7ZH5aEqne9ilQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q08379	uniprotkb:P38261	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	intact:EBI-21567|uniprotkb:D6VQA1|ensemblfungi:YBR102C	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:exo84_yeast(display_long)|uniprotkb:YBR102C(locus name)|uniprotkb:YBR0831(orf name)|uniprotkb:Exocyst complex protein of 84 kDa(gene name synonym)|uniprotkb:EXO84(gene name)|psi-mi:EXO84(display_short)|uniprotkb:USA3(gene name synonym)|uniprotkb:U1 SNP1-associating protein 3(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11528023|imex:IM-24995-595	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N|entrezgene/locuslink:2801(identity)	refseq:NP_009660.1|sgd:S000000306|mint:P38261|dip:DIP-2732N|ensemblfungi:YBR102C(gene)|ensemblfungi:YBR102C_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0000145"(exocyst)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0001927"(exocyst assembly)|go:"GO:0005628"(prospore membrane)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0008104"(protein localization)|go:"GO:0015031"(protein transport)|go:"GO:0030133"(transport vesicle)|go:"GO:0043332"(mating projection tip)|go:"GO:0051601"(exocyst localization)|go:"GO:0090522"(vesicle tethering involved in exocytosis)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR032403|interpro:IPR033961|interpro:IPR042560|interpro:IPR042561|rcsb pdb:2D2S|rcsb pdb:5YFP|rcsb pdb:6VKL|reactome:R-SCE-264876|sgd:YBR102C(identity)	-	-	crc64:1BCDE834466C3536	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2017/05/26	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	rogid:tJ29//zd8m0QGJu94oH597pBVTg559292	intact-crc:0B18A2368E843D32|rigid:CwIf3wQ9preYNggEHdldYdCDy/w	false	sufficient binding region:383-1002	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38260	uniprotkb:Q9UJV3-2	intact:EBI-21563|uniprotkb:D6VQA0|ensemblfungi:YBR101C	intact:EBI-10172526|ensembl:ENSP00000413976	psi-mi:fes1_yeast(display_long)|uniprotkb:YBR101C(locus name)|uniprotkb:YBR0830(orf name)|uniprotkb:Factor exchange for SSA1 protein 1(gene name synonym)|uniprotkb:FES1(gene name)|psi-mi:FES1(display_short)	psi-mi:q9ujv3-2(display_long)|uniprotkb:RING-type E3 ubiquitin transferase MID2(gene name synonym)|uniprotkb:FXY2(gene name synonym)|uniprotkb:Midin-2(gene name synonym)|uniprotkb:Midline defect 2(gene name synonym)|uniprotkb:Midline-2(gene name synonym)|uniprotkb:RING finger protein 60(gene name synonym)|uniprotkb:RNF60(gene name synonym)|uniprotkb:TRIM1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 1(gene name synonym)|uniprotkb:MID2(gene name)|psi-mi:MID2(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11528012|imex:IM-24995-594	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000000305|refseq:NP_009659.3|mint:P38260|dip:DIP-4918N|ensemblfungi:YBR101C(gene)|ensemblfungi:YBR101C_mRNA(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006417"(regulation of translation)|go:"GO:0071629"(cytoplasm protein quality control by the ubiquitin-proteasome system)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013918(Nucleotide exchange factor Fes1)|interpro:IPR016024(Armadillo-type fold)|sgd:YBR101C(identity)	intact:EBI-751983(isoform-parent)|uniprotkb:Q9UJV3-2(isoform-parent)|ensembl:ENSG00000080561(gene)|ensembl:ENST00000443968(transcript)|entrezgene/locuslink:11043(identity)	-	crc64:4A50D069625BA500	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:swXhGbIfsVTGs+eOqqViPwySpI0559292	rogid:/FJ+V2H7SaWon7caUWkEkmHFVxQ9606	intact-crc:BEEABA141CF142B2|rigid:qDyPLF8u93/d6IjBmA8FV6aV7CI	false	-	sufficient binding region:21-705	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38260	uniprotkb:P11142	intact:EBI-21563|uniprotkb:D6VQA0|ensemblfungi:YBR101C	intact:EBI-351896|uniprotkb:Q9H3R6|ensembl:ENSP00000227378|ensembl:ENSP00000432083|ensembl:ENSP00000437125	psi-mi:fes1_yeast(display_long)|uniprotkb:YBR101C(locus name)|uniprotkb:YBR0830(orf name)|uniprotkb:Factor exchange for SSA1 protein 1(gene name synonym)|uniprotkb:FES1(gene name)|psi-mi:FES1(display_short)	psi-mi:hsp7c_human(display_long)|uniprotkb:HSPA8(gene name)|psi-mi:HSPA8(display_short)|uniprotkb:HSC70(gene name synonym)|uniprotkb:HSP73(gene name synonym)|uniprotkb:HSPA10(gene name synonym)|uniprotkb:Heat shock 70 kDa protein 8(gene name synonym)|uniprotkb:Lipopolysaccharide-associated protein 1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11528001|imex:IM-24995-593	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000000305|refseq:NP_009659.3|mint:P38260|dip:DIP-4918N|ensemblfungi:YBR101C(gene)|ensemblfungi:YBR101C_mRNA(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006417"(regulation of translation)|go:"GO:0071629"(cytoplasm protein quality control by the ubiquitin-proteasome system)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013918(Nucleotide exchange factor Fes1)|interpro:IPR016024(Armadillo-type fold)|sgd:YBR101C(identity)	refseq:NP_006588.1|refseq:NP_694881.1|refseq:XP_011541100.1|ensembl:ENSG00000109971(gene)|ensembl:ENST00000227378(transcript)|ensembl:ENST00000532636(transcript)|ensembl:ENST00000534624(transcript)|go:"GO:0000974"(Prp19 complex)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006397"(mRNA processing)|go:"GO:0006457"(protein folding)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008380"(RNA splicing)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030425"(dendrite)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042026"(protein refolding)|go:"GO:0042470"(melanosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0043195"(terminal bouton)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044829"(positive regulation by host of viral genome replication)|go:"GO:0045296"(cadherin binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0055131"(C3HC4-type RING finger domain binding)|go:"GO:0061024"(membrane organization)|go:"GO:0061202"(clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane)|go:"GO:0061635"(regulation of protein complex stability)|go:"GO:0061684"(chaperone-mediated autophagy)|go:"GO:0061738"(late endosomal microautophagy)|go:"GO:0061740"(protein targeting to lysosome involved in chaperone-mediated autophagy)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0098575"(lumenal side of lysosomal membrane)|go:"GO:0098684"(photoreceptor ribbon synapse)|go:"GO:0098690"(glycinergic synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099175"(regulation of postsynapse organization)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099634"(postsynaptic specialization membrane)|go:"GO:0101031"(chaperone complex)|go:"GO:0140545"(protein disaggregase activity)|go:"GO:0140597"(protein carrier chaperone)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902904"(negative regulation of supramolecular fiber organization)|go:"GO:1904589"(regulation of protein import)|go:"GO:1904764"(chaperone-mediated autophagy translocation complex disassembly)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1990832"(slow axonal transport)|go:"GO:1990833"(clathrin-uncoating ATPase activity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|mint:P11142|rcsb pdb:3AGY|rcsb pdb:3AGZ|rcsb pdb:3ESK|rcsb pdb:3FZF|rcsb pdb:3FZH|rcsb pdb:3FZK|rcsb pdb:3FZL|rcsb pdb:3FZM|rcsb pdb:3LDQ|rcsb pdb:3M3Z|rcsb pdb:4H5N|rcsb pdb:4H5R|rcsb pdb:4H5T|rcsb pdb:4H5V|rcsb pdb:4H5W|rcsb pdb:4HWI|rcsb pdb:4KBQ|rcsb pdb:5AQF|rcsb pdb:5AQG|rcsb pdb:5AQH|rcsb pdb:5AQI|rcsb pdb:5AQJ|rcsb pdb:5AQK|rcsb pdb:5AQL|rcsb pdb:5AQM|rcsb pdb:5AQN|rcsb pdb:5AQO|rcsb pdb:5AQP|rcsb pdb:5AQQ|rcsb pdb:5AQR|rcsb pdb:5AQS|rcsb pdb:5AQT|rcsb pdb:5AQU|rcsb pdb:5AQV|rcsb pdb:6B1I|rcsb pdb:6B1M|rcsb pdb:6B1N|rcsb pdb:6ZYJ|reactome:R-HSA-3371453|reactome:R-HSA-3371497|reactome:R-HSA-3371568|reactome:R-HSA-3371571|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-447041|reactome:R-HSA-450408|reactome:R-HSA-6785807|reactome:R-HSA-6798695|reactome:R-HSA-72163|reactome:R-HSA-8856828|reactome:R-HSA-8876725|reactome:R-HSA-888590|reactome:R-HSA-9613354|reactome:R-HSA-9613829|reactome:R-HSA-9615710|dip:DIP-32874N|entrezgene/locuslink:3312(identity)	-	crc64:4A50D069625BA500	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:swXhGbIfsVTGs+eOqqViPwySpI0559292	rogid:0I+wYut3naJRzzgmMSax/1mZZwA9606	intact-crc:7B04C99198A1CE6D|rigid:wjVULKBxWaRB64mV9VWXcOKdgDU	false	-	sufficient binding region:61-646	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8N5R6	uniprotkb:P38234	intact:EBI-740841|intact:EBI-953781|uniprotkb:B3KQ49|uniprotkb:A8K3U4|uniprotkb:A8MPQ6|uniprotkb:A8MV61|uniprotkb:A8MVU9|uniprotkb:Q9H5Q6|uniprotkb:Q8TAX6|intact:EBI-2320546|intact:EBI-11522976	intact:EBI-21445|uniprotkb:D6VQ51|ensemblfungi:YBR052C	psi-mi:ccd33_human(display_long)|uniprotkb:CCDC33(gene name)|psi-mi:CCDC33(display_short)|uniprotkb:Cancer/testis antigen 61(gene name synonym)	psi-mi:rfs1_yeast(display_long)|uniprotkb:YBR052C(locus name)|uniprotkb:YBR0505(orf name)|uniprotkb:RFS1(gene name)|psi-mi:RFS1(display_short)|uniprotkb:RAD55 suppressor protein 1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11527965|imex:IM-24995-589	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_079331.3|interpro:IPR000008(C2 calcium-dependent membrane targeting)|go:"GO:0005777"(peroxisome)|refseq:NP_001274110.1|refseq:NP_877592.2|mint:Q8N5R6|interpro:IPR035892|interpro:IPR039889|entrezgene/locuslink:80125(identity)	refseq:NP_009608.1|sgd:S000000256|mint:P38234|dip:DIP-1761N|ensemblfungi:YBR052C(gene)|ensemblfungi:YBR052C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0010181"(FMN binding)|go:"GO:0045121"(membrane raft)|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|interpro:IPR029039|sgd:YBR052C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2021/11/30	rogid:eEIn7pQyfdHWx8TeLJpYy0i/gww9606	rogid:cb04D8hoVh5fvWEd5oT6iDTL2X0559292	intact-crc:DD27B5CCDA7AC47C|rigid:IRoMaPKSynRAVuLRVfQGYPuTB3o	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38251	uniprotkb:P56279	intact:EBI-15016|uniprotkb:D6VQ88|ensemblfungi:YBR087W	intact:EBI-749995|uniprotkb:Q6IBK7|ensembl:ENSP00000385036|ensembl:ENSP00000450496|ensembl:ENSP00000450701|ensembl:ENSP00000451506	psi-mi:rfc5_yeast(display_long)|uniprotkb:RFC5(gene name)|psi-mi:RFC5(display_short)|uniprotkb:YBR087W(locus name)|uniprotkb:YBR0810(orf name)|uniprotkb:Activator 1 40 kDa subunit(gene name synonym)	psi-mi:tcl1a_human(display_long)|uniprotkb:Protein p14 TCL1(gene name synonym)|uniprotkb:Oncogene TCL-1(gene name synonym)|uniprotkb:TCL1A(gene name)|psi-mi:TCL1A(display_short)|uniprotkb:TCL1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11527983|imex:IM-24995-591	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000000291|refseq:NP_009644.3|go:"GO:0005634"(nucleus)|go:"GO:0005663"(DNA replication factor C complex)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006272"(leading strand elongation)|go:"GO:0006281"(DNA repair)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0031389"(Rad17 RFC-like complex)|go:"GO:0031390"(Ctf18 RFC-like complex)|go:"GO:0031391"(Elg1 RFC-like complex)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR027417|rcsb pdb:1SXJ|reactome:R-SCE-110312|reactome:R-SCE-110320|reactome:R-SCE-176187|reactome:R-SCE-5655862|reactome:R-SCE-5656121|reactome:R-SCE-5656169|reactome:R-SCE-5696397|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-69091|go:"GO:0005524"(ATP binding)|ensemblfungi:YBR087W(gene)|ensemblfungi:YBR087W_mRNA(transcript)|go:"GO:0003677"(DNA binding)|dip:DIP-2531N|mint:P38251|sgd:YBR087W(identity)	refseq:NP_001092195.1|refseq:NP_068801.1|refseq:XP_016877165.1|refseq:XP_016877166.1|dip:DIP-60787N|ensembl:ENSG00000100721(gene)|ensembl:ENST00000402399(transcript)|ensembl:ENST00000554012(transcript)|ensembl:ENST00000555202(transcript)|ensembl:ENST00000556450(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010918"(positive regulation of mitochondrial membrane potential)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|interpro:IPR004832(TCL1/MTCP1)|interpro:IPR036672|rcsb pdb:1JSG|entrezgene/locuslink:8115(identity)	-	crc64:4CD403AF2AFA2961	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:+ZnpxdiC5XBOQaSnExK98LVvFvA559292	rogid:c3GIYkYNb+wWlxn59oU2vpvbfhI9606	intact-crc:AB5DB52FC3931097|rigid:LA6kcR6908IRGzzUl0yjuxi7oxQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38247	uniprotkb:Q9UNE7	intact:EBI-21507|uniprotkb:D6VQ76|ensemblfungi:YBR077C	intact:EBI-357085|uniprotkb:O60526|uniprotkb:Q969U2|uniprotkb:Q9HBT1|uniprotkb:A2IDB9|ensembl:ENSP00000219548	psi-mi:slm4_yeast(display_long)|uniprotkb:YBR077C(locus name)|uniprotkb:YBR0723(orf name)|uniprotkb:GSE complex subunit 1(gene name synonym)|uniprotkb:EGO complex subunit 3(gene name synonym)|uniprotkb:SLM4(gene name)|psi-mi:SLM4(display_short)|uniprotkb:EGO3(gene name synonym)|uniprotkb:GSE1(gene name synonym)	psi-mi:chip_human(display_long)|uniprotkb:CHIP(gene name synonym)|uniprotkb:STUB1(gene name)|psi-mi:STUB1(display_short)|uniprotkb:PP1131(orf name)|uniprotkb:Carboxy terminus of Hsp70-interacting protein(gene name synonym)|uniprotkb:STIP1 homology and U box-containing protein 1(gene name synonym)|uniprotkb:CLL-associated antigen KW-8(gene name synonym)|uniprotkb:Antigen NY-CO-7(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase CHIP(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11527974|imex:IM-24995-590	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009633.3|sgd:S000000281|mint:P38247|dip:DIP-1763N|ensemblfungi:YBR077C(gene)|ensemblfungi:YBR077C_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0007165"(signal transduction)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016237"(lysosomal microautophagy)|go:"GO:0031902"(late endosome membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0071986"(Ragulator complex)|interpro:IPR020233|rcsb pdb:3LGO|rcsb pdb:4FTX|rcsb pdb:4FUW|rcsb pdb:4XPM|rcsb pdb:6JWP|sgd:YBR077C(identity)	dip:DIP-29752N|refseq:NP_005852.2|refseq:NP_001280126.1|ensembl:ENSG00000103266(gene)|ensembl:ENST00000219548(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0002931"(response to ischemia)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030911"(TPR domain binding)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031371"(ubiquitin conjugating enzyme complex)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031943"(regulation of glucocorticoid metabolic process)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|go:"GO:0034605"(cellular response to heat)|go:"GO:0038128"(ERBB2 signaling pathway)|go:"GO:0042405"(nuclear inclusion body)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0046332"(SMAD binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0051604"(protein maturation)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0030579"(ubiquitin-dependent SMAD protein catabolic process)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061684"(chaperone-mediated autophagy)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0071218"(cellular response to misfolded protein)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0090035"(positive regulation of chaperone-mediated protein complex assembly)|go:"GO:0101031"(chaperone complex)|interpro:IPR003613(U box)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019734|interpro:IPR041312|mint:Q9UNE7|rcsb pdb:4KBQ|rcsb pdb:6EFK|rcsb pdb:6NSV|reactome:R-HSA-2173788|reactome:R-HSA-5213460|reactome:R-HSA-5675482|reactome:R-HSA-8863795|reactome:R-HSA-8939902|reactome:R-HSA-8948751|reactome:R-HSA-983168|entrezgene/locuslink:10273(identity)	-	crc64:D64ABDE1CDF265FD	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:BCEWjA3PQvwm3n08QwY0D//TpbA559292	rogid:h4QyIM0TptgkQppPUgiKn68XjP49606	intact-crc:BD73074B9B54C5B3|rigid:iLCs6fLjNe3KPIp16E3mT4+dQwM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38260	uniprotkb:O95273	intact:EBI-21563|uniprotkb:D6VQA0|ensemblfungi:YBR101C	intact:EBI-748961|uniprotkb:A8K3Q0|uniprotkb:A8K3U2|uniprotkb:Q6ZQN9|uniprotkb:Q7Z519|uniprotkb:Q8NBS7|uniprotkb:Q8NBY2|uniprotkb:Q9NS19|uniprotkb:Q9NYH3|uniprotkb:Q9UHX9|ensembl:ENSP00000300213	psi-mi:fes1_yeast(display_long)|uniprotkb:YBR101C(locus name)|uniprotkb:YBR0830(orf name)|uniprotkb:Factor exchange for SSA1 protein 1(gene name synonym)|uniprotkb:FES1(gene name)|psi-mi:FES1(display_short)	psi-mi:ccdb1_human(display_long)|uniprotkb:Grap2 and cyclin-D-interacting protein(gene name synonym)|uniprotkb:Human homolog of Maid(gene name synonym)|uniprotkb:CCNDBP1(gene name)|psi-mi:CCNDBP1(display_short)|uniprotkb:DIP1(gene name synonym)|uniprotkb:GCIP(gene name synonym)|uniprotkb:HHM(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11527992|imex:IM-24995-592	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000000305|refseq:NP_009659.3|mint:P38260|dip:DIP-4918N|ensemblfungi:YBR101C(gene)|ensemblfungi:YBR101C_mRNA(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006417"(regulation of translation)|go:"GO:0071629"(cytoplasm protein quality control by the ubiquitin-proteasome system)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013918(Nucleotide exchange factor Fes1)|interpro:IPR016024(Armadillo-type fold)|sgd:YBR101C(identity)	refseq:NP_036274.3|ensembl:ENSG00000166946(gene)|ensembl:ENST00000300213(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0016604"(nuclear body)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR026907|mint:O95273|rcsb pdb:3AY5|entrezgene/locuslink:23582(identity)	-	crc64:4A50D069625BA500	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:swXhGbIfsVTGs+eOqqViPwySpI0559292	rogid:Vi9aoFc+Mov6P3X6KGmsTxXqxvM9606	intact-crc:DAC18F0E785A405A|rigid:oUDMwT/PEowBr+fIUoVzUYlKGIY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38263	uniprotkb:Q9UKT9	intact:EBI-20304|uniprotkb:D6VQA4|ensemblfungi:YBR105C	intact:EBI-747204|uniprotkb:Q8WWQ9|uniprotkb:Q8WWR0|uniprotkb:Q8WWR1|uniprotkb:Q8WWR2|uniprotkb:Q8WWR3|uniprotkb:Q8N574|uniprotkb:B4DVV5|uniprotkb:Q69BL6|uniprotkb:Q69BL7|uniprotkb:Q69BL8|uniprotkb:Q69BL9|uniprotkb:Q69BM0|uniprotkb:Q69BM1|uniprotkb:Q69BM2|uniprotkb:Q69BM3|uniprotkb:Q69BM5|ensembl:ENSP00000344544	psi-mi:gid4_yeast(display_long)|uniprotkb:VID24(gene name)|psi-mi:VID24(display_short)|uniprotkb:YBR105C(locus name)|uniprotkb:YBR0834(orf name)|uniprotkb:GID4(gene name synonym)|uniprotkb:Glucose-induced degradation protein 4(gene name synonym)	psi-mi:ikzf3_human(display_long)|uniprotkb:ZNFN1A3(gene name synonym)|uniprotkb:Ikaros family zinc finger protein 3(gene name synonym)|uniprotkb:IKZF3(gene name)|psi-mi:IKZF3(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11528092|imex:IM-24995-602	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009663.1|sgd:S000000309|ensemblfungi:YBR105C(gene)|ensemblfungi:YBR105C_mRNA(transcript)|go:"GO:0005773"(vacuole)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0007039"(protein catabolic process in the vacuole)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034657"(GID complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045721"(negative regulation of gluconeogenesis)|go:"GO:0071596"(ubiquitin-dependent protein catabolic process via the N-end rule pathway)|interpro:IPR018618|rcsb pdb:6SWY|dip:DIP-4502N|mint:P38263|sgd:YBR105C(identity)	refseq:NP_001271443.1|refseq:NP_001271444.1|refseq:NP_036613.2|refseq:NP_899051.1|refseq:NP_899052.1|refseq:NP_899053.1|refseq:NP_899054.1|refseq:NP_899055.1|refseq:NP_001271445.1|refseq:NP_001244337.1|refseq:NP_001244338.1|refseq:NP_001244339.1|refseq:NP_001244340.1|refseq:NP_001244341.1|refseq:NP_001244342.1|refseq:NP_001244343.1|ensembl:ENSG00000161405(gene)|ensembl:ENST00000346872(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007498"(mesoderm development)|go:"GO:0009617"(response to bacterium)|go:"GO:0030888"(regulation of B cell proliferation)|go:"GO:0042113"(B cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045577"(regulation of B cell differentiation)|go:"GO:0045619"(regulation of lymphocyte differentiation)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|go:"GO:0046872"(metal ion binding)|dip:DIP-56975N|entrezgene/locuslink:22806(identity)	-	crc64:FF020B239676E0B2	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:ag6caXMIP/qIv27yJtSEmlBoI7g559292	rogid:2Kp6LefSLfK5VIiE6DmQusFIfMY9606	intact-crc:06E565B37C60D9DD|rigid:cTZ1r5urqYii2IhNTMEvDSPo/oQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8TAP6	uniprotkb:P38263	intact:EBI-742887|ensembl:ENSP00000262127|uniprotkb:Q658N5|uniprotkb:Q9H9U7|uniprotkb:B0YJB2|uniprotkb:B4DXG5|uniprotkb:B4DZW1	intact:EBI-20304|uniprotkb:D6VQA4|ensemblfungi:YBR105C	psi-mi:cep76_human(display_long)|uniprotkb:CEP76(gene name)|psi-mi:CEP76(display_short)|uniprotkb:C18orf9(gene name synonym)	psi-mi:gid4_yeast(display_long)|uniprotkb:VID24(gene name)|psi-mi:VID24(display_short)|uniprotkb:YBR105C(locus name)|uniprotkb:YBR0834(orf name)|uniprotkb:GID4(gene name synonym)|uniprotkb:Glucose-induced degradation protein 4(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11528083|imex:IM-24995-601	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_079175.2|ensembl:ENSG00000101624(gene)|ensembl:ENST00000262127(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0046599"(regulation of centriole replication)|interpro:IPR028926|interpro:IPR038765|mint:Q8TAP6|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_001258918.1|entrezgene/locuslink:79959(identity)	refseq:NP_009663.1|sgd:S000000309|ensemblfungi:YBR105C(gene)|ensemblfungi:YBR105C_mRNA(transcript)|go:"GO:0005773"(vacuole)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0007039"(protein catabolic process in the vacuole)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034657"(GID complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045721"(negative regulation of gluconeogenesis)|go:"GO:0071596"(ubiquitin-dependent protein catabolic process via the N-end rule pathway)|interpro:IPR018618|rcsb pdb:6SWY|dip:DIP-4502N|mint:P38263|sgd:YBR105C(identity)	-	-	crc64:FF020B239676E0B2	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:fWzb8oIU35oVWomyDrf8u5sbxUk9606	rogid:ag6caXMIP/qIv27yJtSEmlBoI7g559292	intact-crc:0A7D90E9591C0342|rigid:ZDC0HXWv5sC1tHgjF4wrRkR6x2Q	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38263	uniprotkb:Q5SW96	intact:EBI-20304|uniprotkb:D6VQA4|ensemblfungi:YBR105C	intact:EBI-747813|uniprotkb:A2BHI5|uniprotkb:Q6TQS9|uniprotkb:Q8N2Y0|uniprotkb:Q9UFI9|intact:EBI-28971912|ensembl:ENSP00000363458	psi-mi:gid4_yeast(display_long)|uniprotkb:VID24(gene name)|psi-mi:VID24(display_short)|uniprotkb:YBR105C(locus name)|uniprotkb:YBR0834(orf name)|uniprotkb:GID4(gene name synonym)|uniprotkb:Glucose-induced degradation protein 4(gene name synonym)	psi-mi:arh_human(display_long)|uniprotkb:Autosomal recessive hypercholesterolemia protein(gene name synonym)|uniprotkb:LDLRAP1(gene name)|psi-mi:LDLRAP1(display_short)|uniprotkb:ARH(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11528072|imex:IM-24995-600	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009663.1|sgd:S000000309|ensemblfungi:YBR105C(gene)|ensemblfungi:YBR105C_mRNA(transcript)|go:"GO:0005773"(vacuole)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0007039"(protein catabolic process in the vacuole)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034657"(GID complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045721"(negative regulation of gluconeogenesis)|go:"GO:0071596"(ubiquitin-dependent protein catabolic process via the N-end rule pathway)|interpro:IPR018618|rcsb pdb:6SWY|dip:DIP-4502N|mint:P38263|sgd:YBR105C(identity)	ensembl:ENSP00000363458|refseq:NP_056442.2|go:"GO:0042982"(amyloid precursor protein metabolic process)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0055037"(recycling endosome)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0090118"(receptor-mediated endocytosis involved in cholesterol transport)|go:"GO:0090205"(positive regulation of cholesterol metabolic process)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905581"(positive regulation of low-density lipoprotein particle clearance)|go:"GO:1905602"(positive regulation of receptor-mediated endocytosis involved in cholesterol transport)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|rcsb pdb:2G30|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8964026|reactome:R-HSA-8964038|ensembl:ENSG00000157978(gene)|ensembl:ENST00000374338(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005883"(neurofilament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030276"(clathrin binding)|go:"GO:0030301"(cholesterol transport)|go:"GO:0030424"(axon)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031623"(receptor internalization)|go:"GO:0034383"(low-density lipoprotein particle clearance)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0035612"(AP-2 adaptor complex binding)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0035650"(AP-1 adaptor complex binding)|go:"GO:0042632"(cholesterol homeostasis)|entrezgene/locuslink:26119(identity)	-	crc64:FF020B239676E0B2	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:ag6caXMIP/qIv27yJtSEmlBoI7g559292	rogid:dtBWLcVpVD/R0aKQZr9Nucfa1oo9606	intact-crc:79FBD77F4CA65F58|rigid:fXQk8T6iq+9VLa3t8eummQvUx0o	false	-	sufficient binding region:46-308	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38261	uniprotkb:Q9UKT9	intact:EBI-21567|uniprotkb:D6VQA1|ensemblfungi:YBR102C	intact:EBI-747204|uniprotkb:Q8WWQ9|uniprotkb:Q8WWR0|uniprotkb:Q8WWR1|uniprotkb:Q8WWR2|uniprotkb:Q8WWR3|uniprotkb:Q8N574|uniprotkb:B4DVV5|uniprotkb:Q69BL6|uniprotkb:Q69BL7|uniprotkb:Q69BL8|uniprotkb:Q69BL9|uniprotkb:Q69BM0|uniprotkb:Q69BM1|uniprotkb:Q69BM2|uniprotkb:Q69BM3|uniprotkb:Q69BM5|ensembl:ENSP00000344544	psi-mi:exo84_yeast(display_long)|uniprotkb:YBR102C(locus name)|uniprotkb:YBR0831(orf name)|uniprotkb:Exocyst complex protein of 84 kDa(gene name synonym)|uniprotkb:EXO84(gene name)|psi-mi:EXO84(display_short)|uniprotkb:USA3(gene name synonym)|uniprotkb:U1 SNP1-associating protein 3(gene name synonym)	psi-mi:ikzf3_human(display_long)|uniprotkb:ZNFN1A3(gene name synonym)|uniprotkb:Ikaros family zinc finger protein 3(gene name synonym)|uniprotkb:IKZF3(gene name)|psi-mi:IKZF3(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11528034|imex:IM-24995-596	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009660.1|sgd:S000000306|mint:P38261|dip:DIP-2732N|ensemblfungi:YBR102C(gene)|ensemblfungi:YBR102C_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0000145"(exocyst)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0001927"(exocyst assembly)|go:"GO:0005628"(prospore membrane)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0008104"(protein localization)|go:"GO:0015031"(protein transport)|go:"GO:0030133"(transport vesicle)|go:"GO:0043332"(mating projection tip)|go:"GO:0051601"(exocyst localization)|go:"GO:0090522"(vesicle tethering involved in exocytosis)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR032403|interpro:IPR033961|interpro:IPR042560|interpro:IPR042561|rcsb pdb:2D2S|rcsb pdb:5YFP|rcsb pdb:6VKL|reactome:R-SCE-264876|sgd:YBR102C(identity)	refseq:NP_001271443.1|refseq:NP_001271444.1|refseq:NP_036613.2|refseq:NP_899051.1|refseq:NP_899052.1|refseq:NP_899053.1|refseq:NP_899054.1|refseq:NP_899055.1|refseq:NP_001271445.1|refseq:NP_001244337.1|refseq:NP_001244338.1|refseq:NP_001244339.1|refseq:NP_001244340.1|refseq:NP_001244341.1|refseq:NP_001244342.1|refseq:NP_001244343.1|ensembl:ENSG00000161405(gene)|ensembl:ENST00000346872(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007498"(mesoderm development)|go:"GO:0009617"(response to bacterium)|go:"GO:0030888"(regulation of B cell proliferation)|go:"GO:0042113"(B cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045577"(regulation of B cell differentiation)|go:"GO:0045619"(regulation of lymphocyte differentiation)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|go:"GO:0046872"(metal ion binding)|dip:DIP-56975N|entrezgene/locuslink:22806(identity)	-	crc64:1BCDE834466C3536	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:tJ29//zd8m0QGJu94oH597pBVTg559292	rogid:2Kp6LefSLfK5VIiE6DmQusFIfMY9606	intact-crc:0343A6D76F2ABC55|rigid:vWYb+BjNTJ6s0RM+v9zw/HiC52w	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P14373	uniprotkb:P38263	intact:EBI-719493|uniprotkb:A2BE15|uniprotkb:Q5RJA8|uniprotkb:Q5ST26|uniprotkb:Q6LA73|uniprotkb:Q6NXR9|uniprotkb:Q9BZY6|uniprotkb:Q9UJL3|ensembl:ENSP00000383555|ensembl:ENSP00000392787|ensembl:ENSP00000405229|ensembl:ENSP00000414793|ensembl:ENSP00000366404	intact:EBI-20304|uniprotkb:D6VQA4|ensemblfungi:YBR105C	psi-mi:tri27_human(display_long)|uniprotkb:TRIM27(gene name)|psi-mi:TRIM27(display_short)|uniprotkb:RNF76(gene name synonym)|uniprotkb:RFP(gene name synonym)|uniprotkb:Ret finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 27(gene name synonym)|uniprotkb:RING finger protein 76(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM27(gene name synonym)	psi-mi:gid4_yeast(display_long)|uniprotkb:VID24(gene name)|psi-mi:VID24(display_short)|uniprotkb:YBR105C(locus name)|uniprotkb:YBR0834(orf name)|uniprotkb:GID4(gene name synonym)|uniprotkb:Glucose-induced degradation protein 4(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11528054|imex:IM-24995-598	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006501.1|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0090281"(negative regulation of calcium ion import)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR020457|interpro:IPR035791|interpro:IPR043136|mint:P14373|reactome:R-HSA-3232142|reactome:R-HSA-9635465|reactome:R-HSA-8948751|ensembl:ENSG00000204713(gene)|ensembl:ENSG00000215641(gene)|ensembl:ENSG00000229006(gene)|ensembl:ENSG00000234495(gene)|ensembl:ENSG00000237071(gene)|ensembl:ENST00000377199(transcript)|ensembl:ENST00000400720(transcript)|ensembl:ENST00000431123(transcript)|ensembl:ENST00000435528(transcript)|ensembl:ENST00000437160(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001650"(fibrillar center)|go:"GO:0002820"(negative regulation of adaptive immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|entrezgene/locuslink:5987(identity)	refseq:NP_009663.1|sgd:S000000309|ensemblfungi:YBR105C(gene)|ensemblfungi:YBR105C_mRNA(transcript)|go:"GO:0005773"(vacuole)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0007039"(protein catabolic process in the vacuole)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034657"(GID complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045721"(negative regulation of gluconeogenesis)|go:"GO:0071596"(ubiquitin-dependent protein catabolic process via the N-end rule pathway)|interpro:IPR018618|rcsb pdb:6SWY|dip:DIP-4502N|mint:P38263|sgd:YBR105C(identity)	-	-	crc64:FF020B239676E0B2	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:dsfH5OUghD8KSaTz1SFw9OYVTK49606	rogid:ag6caXMIP/qIv27yJtSEmlBoI7g559292	intact-crc:ADF47847CC6B569A|rigid:Euv0GGsb1JA1Id2ofa27N81yVkI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38263	uniprotkb:Q08379	intact:EBI-20304|uniprotkb:D6VQA4|ensemblfungi:YBR105C	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	psi-mi:gid4_yeast(display_long)|uniprotkb:VID24(gene name)|psi-mi:VID24(display_short)|uniprotkb:YBR105C(locus name)|uniprotkb:YBR0834(orf name)|uniprotkb:GID4(gene name synonym)|uniprotkb:Glucose-induced degradation protein 4(gene name synonym)	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11528043|imex:IM-24995-597	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009663.1|sgd:S000000309|ensemblfungi:YBR105C(gene)|ensemblfungi:YBR105C_mRNA(transcript)|go:"GO:0005773"(vacuole)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0007039"(protein catabolic process in the vacuole)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034657"(GID complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045721"(negative regulation of gluconeogenesis)|go:"GO:0071596"(ubiquitin-dependent protein catabolic process via the N-end rule pathway)|interpro:IPR018618|rcsb pdb:6SWY|dip:DIP-4502N|mint:P38263|sgd:YBR105C(identity)	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N|entrezgene/locuslink:2801(identity)	-	crc64:FF020B239676E0B2	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2017/05/26	rogid:ag6caXMIP/qIv27yJtSEmlBoI7g559292	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	intact-crc:510A630DE6FDD268|rigid:tulP4I+Hi4CulghhzjhObGzAJfk	false	-	sufficient binding region:383-1002	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38263	uniprotkb:Q15654	intact:EBI-20304|uniprotkb:D6VQA4|ensemblfungi:YBR105C	intact:EBI-742327|uniprotkb:O15170|uniprotkb:O15275|uniprotkb:Q9BTB2|uniprotkb:Q9BUE5|uniprotkb:Q9BXP3|uniprotkb:Q9UNT4|uniprotkb:A4D2E7|ensembl:ENSP00000200457|uniprotkb:F2ZC07|uniprotkb:F2ZC08	psi-mi:gid4_yeast(display_long)|uniprotkb:VID24(gene name)|psi-mi:VID24(display_short)|uniprotkb:YBR105C(locus name)|uniprotkb:YBR0834(orf name)|uniprotkb:GID4(gene name synonym)|uniprotkb:Glucose-induced degradation protein 4(gene name synonym)	psi-mi:trip6_human(display_long)|uniprotkb:TRIP6(gene name)|psi-mi:TRIP6(display_short)|uniprotkb:OIP1(gene name synonym)|uniprotkb:Opa-interacting protein 1(gene name synonym)|uniprotkb:Zyxin-related protein 1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11528063|imex:IM-24995-599	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009663.1|sgd:S000000309|ensemblfungi:YBR105C(gene)|ensemblfungi:YBR105C_mRNA(transcript)|go:"GO:0005773"(vacuole)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0007039"(protein catabolic process in the vacuole)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034657"(GID complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045721"(negative regulation of gluconeogenesis)|go:"GO:0071596"(ubiquitin-dependent protein catabolic process via the N-end rule pathway)|interpro:IPR018618|rcsb pdb:6SWY|dip:DIP-4502N|mint:P38263|sgd:YBR105C(identity)	refseq:NP_003293.2|ensembl:ENSP00000200457|ensembl:ENST00000417475|ensembl:ENSP00000413817|ensembl:ENST00000437505|ensembl:ENSP00000410736|ensembl:ENST00000619988|ensembl:ENSP00000479865|ensembl:ENSG00000087077(gene)|ensembl:ENST00000200457(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003723"(RNA binding)|go:"GO:0005149"(interleukin-1 receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0019900"(kinase binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0043009"(chordate embryonic development)|go:"GO:0046872"(metal ion binding)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|interpro:IPR001781(Zinc finger, LIM-type)|mint:Q15654|rcsb pdb:1X61|rcsb pdb:2DLO|dip:DIP-34466N|entrezgene/locuslink:7205(identity)	-	crc64:FF020B239676E0B2	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:ag6caXMIP/qIv27yJtSEmlBoI7g559292	rogid:9Okf3b6sMMwX5awAx991GN9iSsQ9606	intact-crc:1CE0B4D717FF1616|rigid:xb2A35dOA0wawIH6nclhVdXnXro	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38319	uniprotkb:P63279	intact:EBI-20997|uniprotkb:D6VQM0|ensemblfungi:YBR223C	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	psi-mi:tydp1_yeast(display_long)|uniprotkb:TDP1(gene name)|psi-mi:TDP1(display_short)|uniprotkb:YBR1520(orf name)|uniprotkb:YBR223C(locus name)	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11528157|imex:IM-24995-609	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000000427|refseq:NP_009782.3|mint:P38319|dip:DIP-4945N|rcsb pdb:3SQ3|rcsb pdb:3SQ5|rcsb pdb:3SQ7|rcsb pdb:3SQ8|ensemblfungi:YBR223C(gene)|ensemblfungi:YBR223C_mRNA(transcript)|go:"GO:0000012"(single strand break repair)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0004527"(exonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006281"(DNA repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0017005"(3'-tyrosyl-DNA phosphodiesterase activity)|go:"GO:0070260"(5'-tyrosyl-DNA phosphodiesterase activity)|interpro:IPR010347(Tyrosyl-DNA phosphodiesterase)|rcsb pdb:1Q32|sgd:YBR223C(identity)	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N|entrezgene/locuslink:7329(identity)	-	crc64:E84C6685312DEC3F	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:VQHWWxxN+ijh3tjTmmwaPiIfGnU559292	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	intact-crc:1C031154C838F0D8|rigid:z8t5VknMUNe0ysJOGV5SKuS8VNY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9BW62	uniprotkb:P38306	intact:EBI-743591|uniprotkb:A8K5X4|ensembl:ENSP00000369989|ensembl:ENSP00000369991	intact:EBI-20943|uniprotkb:D6VQJ3|ensemblfungi:YBR197C	psi-mi:katl1_human(display_long)|uniprotkb:p60 katanin-like 1(gene name synonym)|uniprotkb:KATNAL1(gene name)|psi-mi:KATNAL1(display_short)	psi-mi:yb47_yeast(display_long)|uniprotkb:YBR1409(orf name)|uniprotkb:YBR197C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11528148|imex:IM-24995-608	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001014402.1|refseq:NP_115492.1|refseq:XP_005266631.1|ensembl:ENSG00000102781(gene)|ensembl:ENST00000380615(transcript)|ensembl:ENST00000380617(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005874"(microtubule)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008017"(microtubule binding)|go:"GO:0008568"(microtubule-severing ATPase activity)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016853"(isomerase activity)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0042802"(identical protein binding)|go:"GO:0051013"(microtubule severing)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR027417|interpro:IPR028594|interpro:IPR028596|interpro:IPR041569|rcsb pdb:6B5C|entrezgene/locuslink:84056(identity)	sgd:S000000401|refseq:NP_009756.1|mint:P38306|dip:DIP-4258N|ensemblfungi:YBR197C(gene)|ensemblfungi:YBR197C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|sgd:YBR197C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Usi4KXsvZnNfMOGuWVSz4mfrTaE9606	rogid:mHsNhEvvGEIB7YFXO768m+tkHeU559292	intact-crc:369BB4F077F933BB|rigid:AfadzUHZucs5QWHSQjJNH2h/fGs	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38302	uniprotkb:Q92733	intact:EBI-20921|uniprotkb:D6VQI3|ensemblfungi:YBR188C	intact:EBI-4397741|uniprotkb:A8K1F7|uniprotkb:O00665|uniprotkb:O00724|uniprotkb:Q5SZ06|ensembl:ENSP00000271526	psi-mi:ntc20_yeast(display_long)|uniprotkb:YBR188C(locus name)|uniprotkb:YBR1316(orf name)|uniprotkb:NTC20(gene name)|psi-mi:NTC20(display_short)|uniprotkb:SNT384(gene name synonym)|uniprotkb:PRP19-associated complex protein 20(gene name synonym)|uniprotkb:Synergistic to PRP19 mutation protein 384(gene name synonym)	psi-mi:prcc_human(display_long)|uniprotkb:PRCC(gene name)|psi-mi:PRCC(display_short)|uniprotkb:TPRC(gene name synonym)|uniprotkb:Papillary renal cell carcinoma translocation-associated gene protein(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11528139|imex:IM-24995-607	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009747.3|sgd:S000000392|mint:P38302|ensemblfungi:YBR188C(gene)|ensemblfungi:YBR188C_mRNA(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000974"(Prp19 complex)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|dip:DIP-1683N|sgd:YBR188C(identity)	refseq:NP_005964.3|ensembl:ENSG00000143294(gene)|ensembl:ENST00000271526(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0016607"(nuclear speck)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR018800|mint:Q92733|reactome:R-HSA-72163|entrezgene/locuslink:5546(identity)	-	crc64:15C5234B25213223	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Ucc4R0lhhhAQfrsXvs+BtCnuJQg559292	rogid:Q6sXpPQm/3mr9HS0XF0VdxLSFzc9606	intact-crc:F33B5866C4BE0697|rigid:CFrGe6z8//a9KmB1lr9NaETc6wU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P14136	uniprotkb:P38265	intact:EBI-744302|uniprotkb:Q53H98|uniprotkb:Q5D055|uniprotkb:Q6ZQS3|uniprotkb:Q7Z5J6|uniprotkb:Q7Z5J7|uniprotkb:Q96KS4|uniprotkb:Q96P18|uniprotkb:Q9UFD0|uniprotkb:B2RD44|uniprotkb:D3DX59|intact:EBI-3909365|uniprotkb:E9PAX3|ensembl:ENSP00000466598|uniprotkb:A7REI1	intact:EBI-21579|uniprotkb:D6VQA6|ensemblfungi:YBR107C	psi-mi:gfap_human(display_long)|uniprotkb:GFAP(gene name)|psi-mi:GFAP(display_short)	psi-mi:cenpl_yeast(display_long)|uniprotkb:YBR107C(locus name)|uniprotkb:YBR0836(orf name)|uniprotkb:Increased minichromosome loss protein 3(gene name synonym)|uniprotkb:Minichromosome maintenance protein 19(gene name synonym)|uniprotkb:IML3(gene name)|psi-mi:IML3(display_short)|uniprotkb:MCM19(gene name synonym)|uniprotkb:CENP-L homolog(gene name synonym)|uniprotkb:Constitutive centromere-associated network protein IML3(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11528101|imex:IM-24995-603	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001124491.1|refseq:NP_001229305.1|refseq:NP_002046.1|ensembl:ENSG00000131095(gene)|ensembl:ENST00000588735(transcript)|go:"GO:0005178"(integrin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0009611"(response to wounding)|go:"GO:0010467"(gene expression)|go:"GO:0010625"(positive regulation of Schwann cell proliferation)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0014002"(astrocyte development)|go:"GO:0019900"(kinase binding)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0031102"(neuron projection regeneration)|go:"GO:0042802"(identical protein binding)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0044297"(cell body)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0051580"(regulation of neurotransmitter uptake)|go:"GO:0060020"(Bergmann glial cell differentiation)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0070779"(D-aspartate import across plasma membrane)|go:"GO:0097450"(astrocyte end-foot)|go:"GO:0098574"(cytoplasmic side of lysosomal membrane)|go:"GO:1904714"(regulation of chaperone-mediated autophagy)|interpro:IPR006821(Intermediate filament, DNA-binding region)|interpro:IPR018039|interpro:IPR027701|interpro:IPR039008|mint:P14136|rcsb pdb:6A9P|reactome:R-HSA-1251985|reactome:R-HSA-9613829|entrezgene/locuslink:2670(identity)	sgd:S000000311|refseq:NP_009665.3|mint:P38265|dip:DIP-5360N|ensemblfungi:YBR107C(gene)|ensemblfungi:YBR107C_mRNA(transcript)|go:"GO:0000940"(outer kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0030437"(ascospore formation)|go:"GO:0034087"(establishment of mitotic sister chromatid cohesion)|go:"GO:0034089"(establishment of meiotic sister chromatid cohesion)|go:"GO:0034090"(maintenance of meiotic sister chromatid cohesion)|go:"GO:0045144"(meiotic sister chromatid segregation)|go:"GO:0051301"(cell division)|go:"GO:0071459"(protein localization to chromosome, centromeric region)|rcsb pdb:4IT3|rcsb pdb:4JE3|rcsb pdb:4KR1|rcsb pdb:6NUW|rcsb pdb:6QLD|rcsb pdb:6QLE|rcsb pdb:6QLF|sgd:YBR107C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Pz4JW0WjMjBYILTDSX9jUmMqWhg9606	rogid:Wq132ybN9X9ZoP+Z9KcTTvkz2t4559292	intact-crc:07E967E84B1CD373|rigid:hWeq1Mm67dM5sUZLU4tMzDOgmUA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38295	uniprotkb:Q9UI14	intact:EBI-20890|uniprotkb:D6VQH2|ensemblfungi:YBR177C	intact:EBI-712367|ensembl:ENSP00000222008|uniprotkb:Q7Z4Y2|uniprotkb:Q9Y3R1	psi-mi:mcfs2_yeast(display_long)|uniprotkb:YBR177C(locus name)|uniprotkb:YBR1239(orf name)|uniprotkb:EHT1(gene name)|psi-mi:EHT1(display_short)|uniprotkb:Alcohol O-acetyltransferase(gene name synonym)|uniprotkb:Ethanol hexanoyl transferase 1(gene name synonym)	psi-mi:praf1_human(display_long)|uniprotkb:PRA1 family protein 1(gene name synonym)|uniprotkb:RABAC1(gene name)|psi-mi:RABAC1(display_short)|uniprotkb:PRA1(gene name synonym)|uniprotkb:PRAF1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11528121|imex:IM-24995-605	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009736.3|sgd:S000000381|interpro:IPR012020(AB-hydrolase YheT, putative)|interpro:IPR000073(Alpha/beta hydrolase fold-1)|interpro:IPR000952(Protein of unknown function UPF0017, hydrolase-like, conserved site)|mint:P38295|interpro:IPR029058|ensemblfungi:YBR177C(gene)|ensemblfungi:YBR177C_mRNA(transcript)|go:"GO:0004026"(alcohol O-acetyltransferase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0008126"(acetylesterase activity)|go:"GO:0017171"(serine hydrolase activity)|go:"GO:0034319"(alcohol O-butanoyltransferase activity)|go:"GO:0034338"(short-chain carboxylesterase activity)|go:"GO:0044255"(cellular lipid metabolic process)|go:"GO:0047372"(acylglycerol lipase activity)|go:"GO:0051792"(medium-chain fatty acid biosynthetic process)|go:"GO:0051793"(medium-chain fatty acid catabolic process)|reactome:R-SCE-1483191|sgd:YBR177C(identity)	refseq:NP_006414.2|ensembl:ENSG00000105404(gene)|ensembl:ENST00000222008(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0070064"(proline-rich region binding)|interpro:IPR004895(Prenylated rab acceptor PRA1)|mint:Q9UI14|entrezgene/locuslink:10567(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:9arzlcrZmkK0VXN7Zw87dAe1Txc559292	rogid:WS2rUY7yXRbR7pqWgfUCbnEiDbg9606	intact-crc:2DCC329C8E7024AC|rigid:PLLUrVsNaFuk2Qvs8fALPfUfHE4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96LP2	uniprotkb:P38271	intact:EBI-10290827|ensembl:ENSP00000283357	intact:EBI-12563|uniprotkb:D6VQC6|ensemblfungi:YBR129C	psi-mi:fa81b_human(display_long)|uniprotkb:FAM81B(gene name)|psi-mi:FAM81B(display_short)	psi-mi:opy1_yeast(display_long)|uniprotkb:OPY1(gene name)|psi-mi:OPY1(display_short)|uniprotkb:YBR129C(locus name)|uniprotkb:YBR1004(orf name)|uniprotkb:Overproduction-induced pheromone-resistant yeast protein 1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11528110|imex:IM-24995-604	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_689761.2|ensembl:ENSG00000153347(gene)|ensembl:ENST00000283357(transcript)|go:"GO:0005634"(nucleus)|interpro:IPR029619|interpro:IPR029620|entrezgene/locuslink:153643(identity)	ensemblfungi:YBR129C(gene)|ensemblfungi:YBR129C_mRNA(transcript)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:1902647"(negative regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016609(Uncharacterised conserved protein UCP013217, Opy1p)|refseq:NP_009687.1|sgd:S000000333|dip:DIP-4768N|sgd:YBR129C(identity)	-	-	crc64:BB4BECCA7C67A5D9	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2020/03/03	rogid:V9VtnYUHk767ZnWUCuuxiUfJF+09606	rogid:97mFgMzTXaBI8NoMtAweXDE8i3s559292	intact-crc:2C609247C1A479F3|rigid:n0Yhpn+39w5sOOefaMKMeX8eiVc	false	sufficient binding region:39-452	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P43365	uniprotkb:P38302	intact:EBI-749530|uniprotkb:Q9NSD3|intact:EBI-10178394|uniprotkb:Q6FHH8|ensembl:ENSP00000350592|ensembl:ENSP00000377447|ensembl:ENSP00000377478	intact:EBI-20921|uniprotkb:D6VQI3|ensemblfungi:YBR188C	psi-mi:magac_human(display_long)|uniprotkb:MAGE-12 antigen(gene name synonym)|uniprotkb:MAGE12F antigen(gene name synonym)|uniprotkb:Cancer/testis antigen 1.12(gene name synonym)|uniprotkb:MAGEA12(gene name)|psi-mi:MAGEA12(display_short)|uniprotkb:MAGE12(gene name synonym)	psi-mi:ntc20_yeast(display_long)|uniprotkb:YBR188C(locus name)|uniprotkb:YBR1316(orf name)|uniprotkb:NTC20(gene name)|psi-mi:NTC20(display_short)|uniprotkb:SNT384(gene name synonym)|uniprotkb:PRP19-associated complex protein 20(gene name synonym)|uniprotkb:Synergistic to PRP19 mutation protein 384(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11528130|imex:IM-24995-606	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001159858.1|refseq:NP_001159859.1|refseq:NP_005358.2|ensembl:ENSG00000213401(gene)|ensembl:ENST00000357916(transcript)|ensembl:ENST00000393869(transcript)|ensembl:ENST00000393900(transcript)|interpro:IPR002190(MAGE protein)|interpro:IPR021072|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|entrezgene/locuslink:4111(identity)	refseq:NP_009747.3|sgd:S000000392|mint:P38302|ensemblfungi:YBR188C(gene)|ensemblfungi:YBR188C_mRNA(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000974"(Prp19 complex)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|dip:DIP-1683N|sgd:YBR188C(identity)	-	-	crc64:15C5234B25213223	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:3/Jxz2VsFOb67RWqWj3xbTrw3s49606	rogid:Ucc4R0lhhhAQfrsXvs+BtCnuJQg559292	intact-crc:892265EB31E5E06B|rigid:vsfcggVYFPxIV6OVMPdpHABFr28	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8N5R6	uniprotkb:P38340	intact:EBI-740841|intact:EBI-953781|uniprotkb:B3KQ49|uniprotkb:A8K3U4|uniprotkb:A8MPQ6|uniprotkb:A8MV61|uniprotkb:A8MVU9|uniprotkb:Q9H5Q6|uniprotkb:Q8TAX6|intact:EBI-2320546|intact:EBI-11522976	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:ccd33_human(display_long)|uniprotkb:CCDC33(gene name)|psi-mi:CCDC33(display_short)|uniprotkb:Cancer/testis antigen 61(gene name synonym)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11528202|imex:IM-24995-614	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_079331.3|interpro:IPR000008(C2 calcium-dependent membrane targeting)|go:"GO:0005777"(peroxisome)|refseq:NP_001274110.1|refseq:NP_877592.2|mint:Q8N5R6|interpro:IPR035892|interpro:IPR039889|entrezgene/locuslink:80125(identity)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	-	-	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2021/11/30	rogid:eEIn7pQyfdHWx8TeLJpYy0i/gww9606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:F545A321A6EBB439|rigid:WXW+UkaLERQjfcPvEM30JXP5Ay8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q13490	uniprotkb:P38339	intact:EBI-514538|uniprotkb:Q16516|uniprotkb:Q4TTG0|uniprotkb:B4E026|ensembl:ENSP00000227758|ensembl:ENSP00000477613	intact:EBI-15065|uniprotkb:D6VQQ7|ensemblfungi:YBR260C	psi-mi:birc2_human(display_long)|uniprotkb:Inhibitor of apoptosis protein 2(gene name synonym)|uniprotkb:TNFR2-TRAF-signaling complex protein 2(gene name synonym)|uniprotkb:IAP homolog B(gene name synonym)|uniprotkb:RING finger protein 48(gene name synonym)|uniprotkb:BIRC2(gene name)|psi-mi:BIRC2(display_short)|uniprotkb:API1(gene name synonym)|uniprotkb:MIHB(gene name synonym)|uniprotkb:RNF48(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase BIRC2(gene name synonym)|uniprotkb:Cellular inhibitor of apoptosis 1(gene name synonym)	psi-mi:rgd1_yeast(display_long)|uniprotkb:RGD1(gene name)|psi-mi:RGD1(display_short)|uniprotkb:YBR260C(locus name)|uniprotkb:YBR1728(orf name)|uniprotkb:Related GAP domain protein 1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11528193|imex:IM-24995-613	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001157.1|refseq:NP_001243095.1|refseq:NP_001243092.1|dip:DIP-33485N|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0045471"(response to ethanol)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051087"(chaperone binding)|go:"GO:0051591"(response to cAMP)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060544"(regulation of necroptotic process)|go:"GO:0060546"(negative regulation of necroptotic process)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070266"(necroptotic process)|go:"GO:0070424"(regulation of nucleotide-binding oligomerization domain containing signaling pathway)|go:"GO:0098770"(FBXO family protein binding)|go:"GO:1901222"(regulation of NIK/NF-kappaB signaling)|go:"GO:1902443"(negative regulation of ripoptosome assembly involved in necroptotic process)|go:"GO:1902523"(positive regulation of protein K63-linked ubiquitination)|go:"GO:1902524"(positive regulation of protein K48-linked ubiquitination)|go:"GO:1902527"(positive regulation of protein monoubiquitination)|go:"GO:2000116"(regulation of cysteine-type endopeptidase activity)|go:"GO:2000377"(regulation of reactive oxygen species metabolic process)|interpro:IPR001315(Caspase Recruitment)|interpro:IPR001370(Proteinase inhibitor I32, inhibitor of apoptosis)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011029(DEATH-like)|interpro:IPR041933|mint:Q13490|rcsb pdb:1QBH|rcsb pdb:2L9M|rcsb pdb:3D9T|rcsb pdb:3D9U|rcsb pdb:3M1D|rcsb pdb:3MUP|rcsb pdb:3OZ1|rcsb pdb:3T6P|rcsb pdb:3UW4|rcsb pdb:4EB9|rcsb pdb:4HY4|rcsb pdb:4HY5|rcsb pdb:4KMN|rcsb pdb:4LGE|rcsb pdb:4LGU|rcsb pdb:4MTI|rcsb pdb:4MU7|rcsb pdb:5M6N|rcsb pdb:6EXW|rcsb pdb:6HPR|rcsb pdb:6W74|rcsb pdb:6W7O|rcsb pdb:6W8I|reactome:R-HSA-111465|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-5213460|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5668541|reactome:R-HSA-5675482|reactome:R-HSA-5676594|reactome:R-HSA-5689880|reactome:R-HSA-937041|ensembl:ENSG00000110330(gene)|ensembl:ENST00000227758(transcript)|ensembl:ENST00000613397(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001741"(XY body)|go:"GO:0001890"(placenta development)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0016740"(transferase activity)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034121"(regulation of toll-like receptor signaling pathway)|go:"GO:0035631"(CD40 receptor complex)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0039535"(regulation of RIG-I signaling pathway)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|entrezgene/locuslink:329(identity)	refseq:NP_009819.1|sgd:S000000464|ensemblfungi:YBR260C(gene)|ensemblfungi:YBR260C_mRNA(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005628"(prospore membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005933"(cellular bud)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007165"(signal transduction)|go:"GO:0010314"(phosphatidylinositol-5-phosphate binding)|go:"GO:0010447"(response to acidic pH)|go:"GO:0030479"(actin cortical patch)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043332"(mating projection tip)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|interpro:IPR000198(RhoGAP)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR027267|interpro:IPR031160|rcsb pdb:4WPC|rcsb pdb:5MY3|reactome:R-SCE-6798695|reactome:R-SCE-8980692|reactome:R-SCE-9013148|reactome:R-SCE-9013405|reactome:R-SCE-9013423|reactome:R-SCE-9035034|dip:DIP-4950N|mint:P38339|sgd:YBR260C(identity)	-	-	crc64:711D9CC717E9111D	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:FOikzyDyDtlv2l69i/WNDNq674A9606	rogid:xHHGufxy5DvB8ngwbICIkYD3DA8559292	intact-crc:7DABD87D5DA1D431|rigid:HaBnP7Z3zycxAx+3jRtT2Z4LiN8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96HH9	uniprotkb:P38331	intact:EBI-2832937|uniprotkb:Q9H753|uniprotkb:D3DSZ3|uniprotkb:B7Z1F2|uniprotkb:B7Z3R1|uniprotkb:B7Z6D8|uniprotkb:B7Z8T2|ensembl:ENSP00000285689	intact:EBI-21083|uniprotkb:D6VQN8|ensemblfungi:YBR242W	psi-mi:grm2b_human(display_long)|uniprotkb:GRAMD2B(gene name)|psi-mi:GRAMD2B(display_short)|uniprotkb:GRAMD3(gene name synonym)|uniprotkb:HCV NS3-transactivated protein 2(gene name synonym)|uniprotkb:NS3TP2(gene name synonym)	psi-mi:yb92_yeast(display_long)|uniprotkb:YBR1627(orf name)|uniprotkb:YBR242W(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11528166|imex:IM-24995-610	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_016865274.1|refseq:NP_001139791.1|refseq:NP_001139792.1|refseq:NP_001139793.1|refseq:NP_001139794.1|refseq:NP_076416.2|refseq:XP_005272120.1|ensembl:ENSG00000155324(gene)|ensembl:ENST00000285689(transcript)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0042802"(identical protein binding)|interpro:IPR004182(GRAM)|interpro:IPR011993(Pleckstrin homology-type)|entrezgene/locuslink:65983(identity)	refseq:NP_009801.1|sgd:S000000446|dip:DIP-4887N|ensemblfungi:YBR242W(gene)|ensemblfungi:YBR242W_mRNA(transcript)|go:"GO:0002953"(5'-deoxynucleotidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009159"(deoxyribonucleoside monophosphate catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0050484"(GMP 5'-nucleotidase activity)|interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|interpro:IPR039356|sgd:YBR242W(identity)	-	-	crc64:CDE8283134B6F48F	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:6UkVJddV5/mHpLX/rk00jMwCA+k9606	rogid:YD0aYpVRCD7mMD3RTxVDksZoE1Q559292	intact-crc:7EAAFE458DD7F26D|rigid:ss4LaWn4LwpKJo9z82Mte3KQUTQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38334	uniprotkb:O43617	intact:EBI-19468|uniprotkb:D6VQQ0|ensemblfungi:YBR254C	intact:EBI-743566|uniprotkb:B2RDN2|uniprotkb:D3DPS2|uniprotkb:A6NDN0|ensembl:ENSP00000362261	psi-mi:trs20_yeast(display_long)|uniprotkb:TRS20(gene name)|psi-mi:TRS20(display_short)|uniprotkb:YBR254C(locus name)|uniprotkb:YBR1722(orf name)|uniprotkb:Transport protein particle 20 kDa subunit(gene name synonym)	psi-mi:tppc3_human(display_long)|uniprotkb:BET3 homolog(gene name synonym)|uniprotkb:TRAPPC3(gene name)|psi-mi:TRAPPC3(display_short)|uniprotkb:BET3(gene name synonym)|uniprotkb:CDABP0066(orf name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11528175|imex:IM-24995-611	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009813.1|sgd:S000000458|ensemblfungi:YBR254C(gene)|ensemblfungi:YBR254C_mRNA(transcript)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006914"(autophagy)|go:"GO:0030008"(TRAPP complex)|go:"GO:0034622"|go:"GO:1990070"(TRAPPI protein complex)|go:"GO:1990071"(TRAPPII protein complex)|go:"GO:1990072"(TRAPPIII protein complex)|interpro:IPR006722(Sedlin)|interpro:IPR011012(Longin-like)|rcsb pdb:7KMT|reactome:R-SCE-204005|reactome:R-SCE-8876198|dip:DIP-1711N|mint:P38334|sgd:YBR254C(identity)	refseq:NP_055223.1|refseq:NP_001257823.1|refseq:NP_001257824.1|refseq:NP_001257825.1|refseq:NP_001257826.1|ensembl:ENSG00000054116(gene)|ensembl:ENST00000373166(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0030008"(TRAPP complex)|go:"GO:0033106"(cis-Golgi network membrane)|interpro:IPR007194("Transport protein particle (TRAPP) component, Bet3")|interpro:IPR016721(TRAPP I complex, Bet3)|interpro:IPR024096|mint:O43617|rcsb pdb:1SZ7|rcsb pdb:2C0J|rcsb pdb:2CFH|rcsb pdb:3KXC|reactome:R-HSA-204005|reactome:R-HSA-8876198|dip:DIP-47627N|entrezgene/locuslink:27095(identity)	-	crc64:82285CAEAC2735D9	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:RaZlF+nwUS/H7Sprxgo1jQ38V+8559292	rogid:YEQWfs0KIBIDkvJ+2Xtz8afsDCc9606	intact-crc:50C901753AE70C6C|rigid:UVDmTrFMJBfUf4/fBI8TwZplmlE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38339	uniprotkb:O14641	intact:EBI-15065|uniprotkb:D6VQQ7|ensemblfungi:YBR260C	intact:EBI-740850|ensembl:ENSP00000005340|uniprotkb:Q53XM0|uniprotkb:D3DTN3	psi-mi:rgd1_yeast(display_long)|uniprotkb:RGD1(gene name)|psi-mi:RGD1(display_short)|uniprotkb:YBR260C(locus name)|uniprotkb:YBR1728(orf name)|uniprotkb:Related GAP domain protein 1(gene name synonym)	psi-mi:dvl2_human(display_long)|uniprotkb:DSH homolog 2(gene name synonym)|uniprotkb:DVL2(gene name)|psi-mi:DVL2(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11528184|imex:IM-24995-612	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009819.1|sgd:S000000464|ensemblfungi:YBR260C(gene)|ensemblfungi:YBR260C_mRNA(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005628"(prospore membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005933"(cellular bud)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007165"(signal transduction)|go:"GO:0010314"(phosphatidylinositol-5-phosphate binding)|go:"GO:0010447"(response to acidic pH)|go:"GO:0030479"(actin cortical patch)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043332"(mating projection tip)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|interpro:IPR000198(RhoGAP)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR027267|interpro:IPR031160|rcsb pdb:4WPC|rcsb pdb:5MY3|reactome:R-SCE-6798695|reactome:R-SCE-8980692|reactome:R-SCE-9013148|reactome:R-SCE-9013405|reactome:R-SCE-9013423|reactome:R-SCE-9035034|dip:DIP-4950N|mint:P38339|sgd:YBR260C(identity)	refseq:NP_004413.1|ensembl:ENSG00000004975(gene)|ensembl:ENST00000005340(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005109"(frizzled binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0007507"(heart development)|go:"GO:0016235"(aggresome)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044340"(canonical Wnt signaling pathway involved in regulation of cell proliferation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0150012"(positive regulation of neuron projection arborization)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008341(Dishevelled-2 region)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:O14641|rcsb pdb:2REY|rcsb pdb:3CBX|rcsb pdb:3CBY|rcsb pdb:3CBZ|rcsb pdb:3CC0|rcsb pdb:4WIP|rcsb pdb:5LNP|rcsb pdb:5SUY|rcsb pdb:5SUZ|rcsb pdb:6IW3|rcsb pdb:6JCK|reactome:R-HSA-201681|reactome:R-HSA-201688|reactome:R-HSA-2028269|reactome:R-HSA-4086400|reactome:R-HSA-4608870|reactome:R-HSA-4641258|reactome:R-HSA-4641262|reactome:R-HSA-5099900|reactome:R-HSA-5368598|reactome:R-HSA-5663220|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9673324|ensembl:ENSP00000005340|dip:DIP-34433N|entrezgene/locuslink:1856(identity)	-	crc64:711D9CC717E9111D	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:xHHGufxy5DvB8ngwbICIkYD3DA8559292	rogid:2Vdc8oRnT4Mz/j+EXQXrL3AszOc9606	intact-crc:10AEE1B579DA52FF|rigid:NC2obhGm8+/XWATnLm6RDtrAfj8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38340	uniprotkb:P04179	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-716989|intact:EBI-1058533|uniprotkb:P78434|uniprotkb:Q16792|uniprotkb:Q5TCM1|uniprotkb:Q96EE6|uniprotkb:Q9P2Z3|uniprotkb:B2R7R1|uniprotkb:E1P5A9|uniprotkb:B3KUK2|uniprotkb:B4E3K9|intact:EBI-11528264|uniprotkb:B4DL20|ensembl:ENSP00000356022|ensembl:ENSP00000446252	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:sodm_human(display_long)|uniprotkb:SOD2(gene name)|psi-mi:SOD2(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11528262|imex:IM-24995-619	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	refseq:NP_001019637.1|refseq:NP_000627.2|refseq:NP_001019636.1|refseq:NP_001309743.1|refseq:NP_001309744.1|refseq:NP_001309746.1|refseq:NP_001309748.1|refseq:NP_001309749.1|ensembl:ENSG00000112096(gene)|ensembl:ENST00000367055(transcript)|ensembl:ENST00000538183(transcript)|go:"GO:0000303"(response to superoxide)|go:"GO:0001315"(age-dependent response to reactive oxygen species)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0003069"(acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure)|go:"GO:0003677"(DNA binding)|go:"GO:0004784"(superoxide dismutase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006801"(superoxide metabolic process)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009314"(response to radiation)|go:"GO:0009409"(response to cold)|go:"GO:0010042"(response to manganese ion)|go:"GO:0010043"(response to zinc ion)|go:"GO:0010269"(response to selenium ion)|go:"GO:0010729"(positive regulation of hydrogen peroxide biosynthetic process)|go:"GO:0014823"(response to activity)|go:"GO:0019430"(removal of superoxide radicals)|go:"GO:0019825"(oxygen binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030145"(manganese ion binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0032364"(oxygen homeostasis)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0033591"(response to L-ascorbic acid)|go:"GO:0034021"(response to silicon dioxide)|go:"GO:0035900"(response to isolation stress)|go:"GO:0035902"(response to immobilization stress)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042802"(identical protein binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0050665"(hydrogen peroxide biosynthetic process)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071000"(response to magnetism)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:1902176"(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1902631"(negative regulation of membrane hyperpolarization)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|go:"GO:1905932"(positive regulation of vascular associated smooth muscle cell differentiation involved in phenotypic switching)|interpro:IPR001189(Manganese and iron superoxide dismutase)|interpro:IPR019831|interpro:IPR019832|interpro:IPR019833|interpro:IPR036314|interpro:IPR036324|mint:P04179|rcsb pdb:1AP5|rcsb pdb:1AP6|rcsb pdb:1EM1|rcsb pdb:1JA8|rcsb pdb:1LUV|rcsb pdb:1LUW|rcsb pdb:1MSD|rcsb pdb:1N0J|rcsb pdb:1N0N|rcsb pdb:1PL4|rcsb pdb:1PM9|rcsb pdb:1QNM|rcsb pdb:1SZX|rcsb pdb:1VAR|rcsb pdb:1XDC|rcsb pdb:1XIL|rcsb pdb:1ZTE|rcsb pdb:1ZUQ|rcsb pdb:2ADP|rcsb pdb:2ADQ|rcsb pdb:2GDS|rcsb pdb:2P4K|rcsb pdb:2QKA|rcsb pdb:2QKC|rcsb pdb:3C3S|rcsb pdb:3C3T|rcsb pdb:5GXO|rcsb pdb:5T30|rcsb pdb:5VF9|rcsb pdb:7KKS|rcsb pdb:7KKU|rcsb pdb:7KKW|rcsb pdb:7KLB|reactome:R-HSA-2151201|reactome:R-HSA-3299685|reactome:R-HSA-8862803|reactome:R-HSA-8950505|rcsb pdb:1ZSP|reactome:R-HSA-9615017|entrezgene/locuslink:6648(identity)	-	crc64:66699F37B0013088	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2018/02/26	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:W5bvoLylgk4nEcm5peimceKIBbE9606	intact-crc:FCB26006C6DB0FF5|rigid:exJgdTfj27ljprbIWmnpTK9FJm4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:A0A0A0MQS1	uniprotkb:P38340	intact:EBI-11528247|ensembl:ENSP00000220966|ensembl:ENSP00000484458	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:a0a0a0mqs1_human(display_long)|uniprotkb:PYCR3(gene name)|psi-mi:PYCR3(display_short)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11528251|imex:IM-24995-618	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_075566.2|ensembl:ENSG00000104524(gene)|ensembl:ENSG00000276657(gene)|ensembl:ENST00000220966(transcript)|ensembl:ENST00000616663(transcript)|go:"GO:0004735"(pyrroline-5-carboxylate reductase activity)|go:"GO:0005829"(cytosol)|go:"GO:0045171"(intercellular bridge)|go:"GO:0055129"(L-proline biosynthetic process)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000304(Delta 1-pyrroline-5-carboxylate reductase)|interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|interpro:IPR028939|interpro:IPR029036|interpro:IPR036291|entrezgene/locuslink:65263(identity)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	-	-	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:kN384/dufzrR3P6KOXbFMYoj0zc9606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:A9C3B9ADC7698F17|rigid:/WYBpOjvXMEfItB+e7NBTIhhtco	false	sufficient binding region:13-286	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38340	intact:EBI-11528211	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	-	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:enox2(display_short)|psi-mi:EBI-11528211(display_long)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11528214|imex:IM-24995-615	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	entrezgene/locuslink:10495(identity)	-	crc64:66699F37B0013088	no-uniprot-update:	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:mwLMSKBYuz2EZOAkdg8N9MLSkXE9606	intact-crc:30B8D02164ED12DB|rigid:PeR0wVW3EbiAR3iK/a2zYQ0y6iU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38340	intact:EBI-11528223	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	-	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:znf471(display_short)|psi-mi:EBI-11528223(display_long)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11528226|imex:IM-24995-616	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	entrezgene/locuslink:57573(identity)	-	crc64:66699F37B0013088	no-uniprot-update:	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:x1KdEVhuKo5sZGVPBGE9eyTup9w9606	intact-crc:51E8095E8083D566|rigid:6nI/DovSV6EE/RcJSsHhQqjEH8g	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96A10	uniprotkb:P38340	intact:EBI-10486892|intact:EBI-11528237|ensembl:ENSP00000488921	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:q96a10_human(display_long)|uniprotkb:ERVK3-1(gene name)|psi-mi:ERVK3-1(display_short)|uniprotkb:hCG_2043597(orf name)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11528235|imex:IM-24995-617	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000142396(gene)|ensembl:ENST00000427361(transcript)|entrezgene/locuslink:113386(identity)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	-	-	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/17	rogid:UGl9ZpnDNz58eECRstJXxM5bj9I9606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:45CE1D0ACA0D9F9C|rigid:YJyo2r0ijA0z/uAq/mMlfx5VD3o	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q7Z6G3-2	uniprotkb:P38340	intact:EBI-10172876|ensembl:ENSP00000457354|intact:EBI-14062040	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:q7z6g3-2(display_long)|uniprotkb:EFCBP2(gene name synonym)|uniprotkb:Neuronal calcium-binding protein 2(gene name synonym)|uniprotkb:Synaptotagmin-interacting protein 2(gene name synonym)|uniprotkb:NECAB2(gene name)|psi-mi:NECAB2(display_short)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11528301|imex:IM-24995-622	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000103154(gene)|ensembl:ENST00000565691(transcript)|uniprotkb:Q7Z6G3-2(isoform-parent)|intact:EBI-950070(isoform-parent)|entrezgene/locuslink:54550(identity)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	-	-	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:4S7oIx6h+mKzV3EPxqcfMNqaNko9606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:6AD53F256674DF97|rigid:HePbFZ6mzdKTou/1BHktJZUUsEk	false	sufficient binding region:65-303	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:E7EUC7	uniprotkb:P38340	intact:EBI-11528286|ensembl:ENSP00000411803	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:e7euc7_human(display_long)|uniprotkb:UGP2(gene name)|psi-mi:UGP2(display_short)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11528290|imex:IM-24995-621	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000169764(gene)|ensembl:ENST00000445915(transcript)|go:"GO:0003983"("UTP:glucose-1-phosphate uridylyltransferase activity")|go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0006011"(UDP-glucose metabolic process)|interpro:IPR002618(UTP--glucose-1-phosphate uridylyltransferase)|interpro:IPR016267(UTP--glucose-1-phosphate uridylyltransferase, subgroup)|interpro:IPR029044|entrezgene/locuslink:7360(identity)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	-	-	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:+NfRORYv+EzUaQOJJ7vdI/Plv5o9606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:48B4084E8FD6C152|rigid:H37AqMtrt28Esz0gavvvEKcGlvM	false	sufficient binding region:21-517	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38340	uniprotkb:O00463	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-523498|ensembl:ENSP00000261464|ensembl:ENSP00000336825|ensembl:ENSP00000355971|uniprotkb:Q6FHY1|uniprotkb:B4DIS9|uniprotkb:B4E0A2	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:traf5_human(display_long)|uniprotkb:RING finger protein 84(gene name synonym)|uniprotkb:TRAF5(gene name)|psi-mi:TRAF5(display_short)|uniprotkb:RNF84(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11528312|imex:IM-24995-623	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	refseq:NP_001306136.1|refseq:XP_011508261.1|refseq:XP_011508262.1|ensembl:ENSG00000082512(gene)|ensembl:ENST00000261464(transcript)|ensembl:ENST00000336184(transcript)|ensembl:ENST00000367004(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031996"(thioesterase binding)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035631"(CD40 receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0097400"(interleukin-17-mediated signaling pathway)|interpro:IPR001293(Zinc finger, TRAF-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|interpro:IPR012227(TNF receptor-associated factor TRAF)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018957|interpro:IPR027130|interpro:IPR043211|mint:O00463|rcsb pdb:7L3L|refseq:NP_001029082.1|refseq:NP_004610.1|refseq:NP_665702.1|refseq:XP_016857710.1|entrezgene/locuslink:7188(identity)	-	crc64:66699F37B0013088	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:xPAQGevMJLEAPcT6eX3n304eSOw9606	intact-crc:EBBC03374C8D924F|rigid:pkuLBc2UxLhn82KLCoJBiJlN04M	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38340	uniprotkb:O15217	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-752440|uniprotkb:Q5T7Q8|uniprotkb:Q9BX18|uniprotkb:Q9H414|uniprotkb:B2RD15|uniprotkb:Q6P4G1|ensembl:ENSP00000359998|ensembl:ENSP00000360002	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:gsta4_human(display_long)|uniprotkb:Glutathione S-transferase A4-4(gene name synonym)|uniprotkb:GST class-alpha member 4(gene name synonym)|uniprotkb:GSTA4(gene name)|psi-mi:GSTA4(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11528330|imex:IM-24995-625	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	refseq:NP_001503.1|refseq:XP_005249092.1|ensembl:ENSG00000170899(gene)|ensembl:ENST00000370959(transcript)|ensembl:ENST00000370963(transcript)|go:"GO:0004364"(glutathione transferase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0006805"(xenobiotic metabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|interpro:IPR003080(Glutathione S-transferase, alpha class)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR036249|interpro:IPR036282|interpro:IPR040079|rcsb pdb:1GUL|rcsb pdb:1GUM|rcsb pdb:3IK7|reactome:R-HSA-156590|entrezgene/locuslink:2941(identity)	-	crc64:66699F37B0013088	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:9yVcqmJL64S0kxOW5RJWbOJ25bo9606	intact-crc:CB08391B41AA890B|rigid:CQe1YtkJPmZO9D7RLFGMIU2cnpo	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38340	uniprotkb:O00635	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-2130415|uniprotkb:B2R862|ensembl:ENSP00000349596	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:tri38_human(display_long)|uniprotkb:TRIM38(gene name)|psi-mi:TRIM38(display_short)|uniprotkb:RNF15(gene name synonym)|uniprotkb:RORET(gene name synonym)|uniprotkb:RING finger protein 15(gene name synonym)|uniprotkb:Zinc finger protein RoRet(gene name synonym)|uniprotkb:Tripartite motif-containing protein 38(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM38(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11528321|imex:IM-24995-624	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	refseq:NP_006346.1|refseq:XP_005248856.1|refseq:XP_005248857.1|ensembl:ENSG00000112343(gene)|ensembl:ENST00000357085(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046598"(positive regulation of viral entry into host cell)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR035790|interpro:IPR043136|reactome:R-HSA-877300|entrezgene/locuslink:10475(identity)	-	crc64:66699F37B0013088	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:Zh4X/6v/qKZlDkMV6hhn7OsvPnQ9606	intact-crc:414D1BEDBE27C1D0|rigid:PSSGJVXhFQXVtirX3AU6PNf5XwQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:A0A0R4J2E4	uniprotkb:P38340	intact:EBI-11525602|ensembl:ENSP00000324292	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:a0a0r4j2e4_human(display_long)|uniprotkb:FBF1(gene name)|psi-mi:FBF1(display_short)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11528275|imex:IM-24995-620	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000188878(gene)|ensembl:ENST00000319129(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0060271"(cilium assembly)|go:"GO:0090162"(establishment of epithelial cell polarity)|go:"GO:0097539"(ciliary transition fiber)|interpro:IPR033561|entrezgene/locuslink:85302(identity)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	-	-	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/03/16	rogid:N4h8foiP1+HSYZRE7i66zhtqKlQ9606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:048FB21D6B88A50C|rigid:V5Ib2iPlTNrAWfrrK9eBf406bCo	false	sufficient binding region:649-1092	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38340	uniprotkb:O95045-2	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-11528386|ensembl:ENSP00000474090	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:o95045-2(display_long)|uniprotkb:UPP2(gene name)|psi-mi:UPP2(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11528384|imex:IM-24995-631	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	intact:EBI-10191025(isoform-parent)|ensembl:ENSG00000007001(gene)|ensembl:ENST00000605860(transcript)|uniprotkb:O95045-2(isoform-parent)|entrezgene/locuslink:151531(identity)	-	crc64:66699F37B0013088	isoform-comment:No experimental confirmation available.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:owY6a3SJ4JVsFePCTPW+NLGK6QQ9606	intact-crc:A3180B3C9074C45B|rigid:V72wliDv5yx9hOM+q/HouxwfR5E	false	-	sufficient binding region:58-374	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38340	uniprotkb:O75525	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-722504|uniprotkb:Q6NUL8|uniprotkb:Q9UPA8|ensembl:ENSP00000348108	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:khdr3_human(display_long)|uniprotkb:Sam68-like mammalian protein 2(gene name synonym)|uniprotkb:Sam68-like phosphotyrosine protein(gene name synonym)|uniprotkb:RNA-binding protein T-Star(gene name synonym)|uniprotkb:KHDRBS3(gene name)|psi-mi:KHDRBS3(display_short)|uniprotkb:SALP(gene name synonym)|uniprotkb:SLM2(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11528375|imex:IM-24995-630	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	refseq:NP_006549.1|ensembl:ENSG00000131773(gene)|ensembl:ENST00000355849(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR032335|interpro:IPR032571|interpro:IPR036612|mint:O75525|rcsb pdb:5EL3|rcsb pdb:5ELR|rcsb pdb:5ELS|rcsb pdb:5ELT|rcsb pdb:5EMO|reactome:R-HSA-8849468|entrezgene/locuslink:10656(identity)	-	crc64:66699F37B0013088	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:9ZoB3JVp0Q9nxeFRsmWhNThzWoE9606	intact-crc:4DA11B6119498E60|rigid:HE8C5amJM/2YjlkjyDW3gJAZjtA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O43791	uniprotkb:P38340	intact:EBI-743549|uniprotkb:Q53HJ1|uniprotkb:B2R6S3|uniprotkb:D3DTW7|ensembl:ENSP00000240327|ensembl:ENSP00000377001|ensembl:ENSP00000420908|ensembl:ENSP00000424119|ensembl:ENSP00000425905|ensembl:ENSP00000426986|ensembl:ENSP00000499562	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:spop_human(display_long)|uniprotkb:HIB homolog 1(gene name synonym)|uniprotkb:Roadkill homolog 1(gene name synonym)|uniprotkb:SPOP(gene name)|psi-mi:SPOP(display_short)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11528339|imex:IM-24995-626	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001007227.1|refseq:NP_001007228.1|refseq:NP_001007229.1|refseq:NP_001007230.1|refseq:NP_001007231.1|refseq:NP_003554.1|refseq:XP_005257780.1|refseq:XP_005257781.1|ensembl:ENSG00000121067(gene)|ensembl:ENST00000347630(transcript)|ensembl:ENST00000393328(transcript)|ensembl:ENST00000503676(transcript)|ensembl:ENST00000504102(transcript)|ensembl:ENST00000509079(transcript)|ensembl:ENST00000514121(transcript)|ensembl:ENST00000665825(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0016607"(nuclear speck)|go:"GO:0030162"(regulation of proteolysis)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR034089|mint:O43791|rcsb pdb:2CR2|rcsb pdb:3HQH|rcsb pdb:3HQI|rcsb pdb:3HQL|rcsb pdb:3HQM|rcsb pdb:3HSV|rcsb pdb:3HTM|rcsb pdb:3HU6|rcsb pdb:3IVB|rcsb pdb:3IVQ|rcsb pdb:3IVV|rcsb pdb:4EOZ|rcsb pdb:4HS2|rcsb pdb:4J8Z|rcsb pdb:4O1V|rcsb pdb:6F8F|rcsb pdb:6F8G|rcsb pdb:6I41|rcsb pdb:6I5P|rcsb pdb:6I68|rcsb pdb:6I7A|rcsb pdb:7D3D|rcsb pdb:7LIN|rcsb pdb:7LIO|rcsb pdb:7LIP|rcsb pdb:7LIQ|reactome:R-HSA-5632684|go:"GO:0005634"(nucleus)|refseq:XP_016880693.1|dip:DIP-50517N|entrezgene/locuslink:8405(identity)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	-	-	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:PC9ofpvk14xwTnnqT590/YRnx/49606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:83CD54562E2559A0|rigid:t/pDXBo/dfZ4YElZ7GMLcsDBsrA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38340	uniprotkb:O60547	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-746373|uniprotkb:O75357|uniprotkb:Q5T954|uniprotkb:Q6FH09|uniprotkb:Q9UGZ3|uniprotkb:Q9UJK9|ensembl:ENSP00000370194|intact:EBI-10968896|uniprotkb:E9PI88	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:gmds_human(display_long)|uniprotkb:GDP-D-mannose dehydratase(gene name synonym)|uniprotkb:GMDS(gene name)|psi-mi:GMDS(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11528357|imex:IM-24995-628	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	refseq:NP_001491.1|ensembl:ENSG00000112699(gene)|ensembl:ENST00000380815(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0008446"(GDP-mannose 4,6-dehydratase activity)|go:"GO:0019673"(GDP-mannose metabolic process)|go:"GO:0042351"('de novo' GDP-L-fucose biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070401"(NADP+ binding)|interpro:IPR006368(GDP-mannose 4,6-dehydratase)|interpro:IPR016040("NAD(P)-binding")|interpro:IPR036291|rcsb pdb:1T2A|rcsb pdb:5IN4|rcsb pdb:5IN5|rcsb pdb:6GPJ|rcsb pdb:6GPK|rcsb pdb:6GPL|rcsb pdb:6Q94|reactome:R-HSA-6787639|refseq:NP_001240775.1|entrezgene/locuslink:2762(identity)	-	crc64:66699F37B0013088	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:phGw3/m75gYQcBlRP3OXK4mQvhM9606	intact-crc:B0A9E98F82F7B6B1|rigid:PrxLMY8mTgPT6dYfmKllhPebQmA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38340	uniprotkb:O60232	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-741415|ensembl:ENSP00000312318	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:znrd2_human(display_long)|uniprotkb:ZNRD2(gene name)|psi-mi:ZNRD2(display_short)|uniprotkb:Autoantigen p27(gene name synonym)|uniprotkb:SSSCA1(gene name synonym)|uniprotkb:Sjoegren syndrome/scleroderma autoantigen 1(gene name synonym)|uniprotkb:Zinc ribbon domain-containing protein 2(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11528348|imex:IM-24995-627	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	refseq:NP_006387.1|ensembl:ENSG00000173465(gene)|ensembl:ENST00000309328(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0051301"(cell division)|interpro:IPR009563(Sjogrens syndrome scleroderma autoantigen 1)|rcsb pdb:6HCZ|entrezgene/locuslink:10534(identity)	-	crc64:66699F37B0013088	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:Uou80pZneoL39/0YYzb1TAbiB2I9606	intact-crc:9CC1094824C5BF2A|rigid:r8e1XvMTUwwFv0utOolzotby7J8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38340	uniprotkb:O75150	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-744408|uniprotkb:Q6AHZ6|uniprotkb:Q6N005|uniprotkb:Q7L3T6|uniprotkb:Q8N615|uniprotkb:Q96T18|uniprotkb:Q9BSV9|uniprotkb:Q9HC82|ensembl:ENSP00000325677|uniprotkb:A0A024QZG0	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:bre1b_human(display_long)|uniprotkb:95 kDa retinoblastoma-associated protein(gene name synonym)|uniprotkb:RING finger protein 40(gene name synonym)|uniprotkb:RNF40(gene name)|psi-mi:RNF40(display_short)|uniprotkb:BRE1B(gene name synonym)|uniprotkb:KIAA0661(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase BRE1B(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11528366|imex:IM-24995-629	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	refseq:NP_001273501.1|refseq:NP_001193962.1|refseq:NP_001193963.1|refseq:NP_055586.1|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|go:"GO:1902916"(positive regulation of protein polyubiquitination)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013956(E3 ubiquitin ligase, BRE1)|interpro:IPR017907|mint:O75150|reactome:R-HSA-8866654|go:"GO:0046872"(metal ion binding)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0043679"(axon terminus)|go:"GO:0044877"(protein-containing complex binding)|ensembl:ENSG00000103549(gene)|ensembl:ENST00000324685(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016020"(membrane)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0033503"(HULC complex)|entrezgene/locuslink:9810(identity)	-	crc64:66699F37B0013088	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2018/09/18	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:POkQZhEBe4cw3Y9V3YOwJDgvYJ89606	intact-crc:CE577B93DBB73288|rigid:Sy3yc2wsAABEI+8dEkNmd7HhUCI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P02792	uniprotkb:P38340	intact:EBI-713279|uniprotkb:Q7Z2W1|uniprotkb:Q9BTZ8|ensembl:ENSP00000366525|uniprotkb:B2R4B9|uniprotkb:Q6IBT7|uniprotkb:Q86WI9|uniprotkb:Q8WU07|uniprotkb:Q96AU9|uniprotkb:Q96CU0	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:fril_human(display_long)|uniprotkb:FTL(gene name)|psi-mi:FTL(display_short)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11528444|imex:IM-24995-637	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000137.2|ensembl:ENSG00000087086(gene)|ensembl:ENST00000331825(transcript)|go:"GO:0005506"(iron ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006826"(iron ion transport)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0006880"(intracellular sequestering of iron ion)|go:"GO:0008043"(intracellular ferritin complex)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008199"(ferric iron binding)|go:"GO:0016020"(membrane)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0042802"(identical protein binding)|go:"GO:0044754"(autolysosome)|go:"GO:0055072"(iron ion homeostasis)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001519(Ferritin, N-terminal)|interpro:IPR008331(Ferritin and Dps)|interpro:IPR009040(Ferritin-like)|interpro:IPR009078(Ferritin/ribonucleotide reductase-like)|interpro:IPR012347(Ferritin-related)|interpro:IPR014034(Ferritin, conserved site)|mint:P02792|rcsb pdb:2FFX|rcsb pdb:2FG4|rcsb pdb:2FG8|rcsb pdb:3KXU|rcsb pdb:4V6B|rcsb pdb:5LG8|rcsb pdb:6TR9|rcsb pdb:6TS0|rcsb pdb:6TS1|rcsb pdb:6TSA|rcsb pdb:6TSF|rcsb pdb:6TSJ|rcsb pdb:6WX6|reactome:R-HSA-3000480|reactome:R-HSA-432722|reactome:R-HSA-6798695|reactome:R-HSA-917937|dip:DIP-31248N|entrezgene/locuslink:2512(identity)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	-	-	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:+mbnoETQ9TuBZg8Gc09nwAjwKTE9606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:094D5F48A5088DCE|rigid:WAT4Ve4kETxjryeBc7GwTF2nUqk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P00492	uniprotkb:P38340	intact:EBI-748210|uniprotkb:A6NHF0|uniprotkb:B2R8M9|ensembl:ENSP00000298556	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:hprt_human(display_long)|uniprotkb:HPRT1(gene name)|psi-mi:HPRT1(display_short)|uniprotkb:HPRT(gene name synonym)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11528435|imex:IM-24995-636	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000185.1|ensembl:ENSG00000165704(gene)|ensembl:ENST00000298556(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001913"(T cell mediated cytotoxicity)|go:"GO:0001975"(response to amphetamine)|go:"GO:0004422"(hypoxanthine phosphoribosyltransferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006164"(purine nucleotide biosynthetic process)|go:"GO:0006166"(purine ribonucleoside salvage)|go:"GO:0006168"(adenine salvage)|go:"GO:0006178"(guanine salvage)|go:"GO:0007625"(grooming behavior)|go:"GO:0007626"(locomotory behavior)|go:"GO:0021756"(striatum development)|go:"GO:0021895"(cerebral cortex neuron differentiation)|go:"GO:0021954"(central nervous system neuron development)|go:"GO:0032263"(GMP salvage)|go:"GO:0032264"(IMP salvage)|go:"GO:0042417"(dopamine metabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043103"(hypoxanthine salvage)|go:"GO:0045964"(positive regulation of dopamine metabolic process)|go:"GO:0046038"(GMP catabolic process)|go:"GO:0046040"(IMP metabolic process)|go:"GO:0046100"(hypoxanthine metabolic process)|go:"GO:0046651"(lymphocyte proliferation)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0052657"(guanine phosphoribosyltransferase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000836(Phosphoribosyltransferase)|interpro:IPR005904(Hypoxanthine phosphoribosyl transferase)|interpro:IPR029057|mint:P00492|rcsb pdb:1BZY|rcsb pdb:1D6N|rcsb pdb:1HMP|rcsb pdb:1Z7G|go:"GO:0048813"(dendrite morphogenesis)|rcsb pdb:2VFA|rcsb pdb:3GEP|rcsb pdb:3GGC|rcsb pdb:3GGJ|rcsb pdb:4IJQ|rcsb pdb:4KN6|rcsb pdb:4RAB|rcsb pdb:4RAC|rcsb pdb:4RAD|rcsb pdb:4RAN|rcsb pdb:4RAO|rcsb pdb:4RAQ|rcsb pdb:5BRN|rcsb pdb:5BSK|rcsb pdb:5HIA|rcsb pdb:5W8V|rcsb pdb:6BNJ|reactome:R-HSA-74217|entrezgene/locuslink:3251(identity)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	-	-	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:w87Sv/qOAkHFqJm0vu0Ayqlz7TA9606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:D73F07AAA3B0729D|rigid:kN3HSjFHCL+psSPe3dh3+6GQJ0o	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38340	uniprotkb:O95073-2	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-10696047	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:o95073-2(display_long)|uniprotkb:FSBP(gene name)|psi-mi:FSBP(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11528399|imex:IM-24995-632	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	intact:EBI-1059030(isoform-parent)|uniprotkb:O95073-2(isoform-parent)|entrezgene/locuslink:25788(identity)	-	crc64:66699F37B0013088	isoform-comment:No experimental confirmation available.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:j4ktleFZa7rAjRFENAKAGdAd+Fs9606	intact-crc:830DF462CF43D93A|rigid:3CHju8AVHoaJuwXoNLMo4eK2jk4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38340	uniprotkb:O95199	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-742404|uniprotkb:B2RDW8|ensembl:ENSP00000345144	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:rcbt2_human(display_long)|uniprotkb:RCBTB2(gene name)|psi-mi:RCBTB2(display_short)|uniprotkb:CHC1L(gene name synonym)|uniprotkb:RLG(gene name synonym)|uniprotkb:Regulator of chromosome condensation and BTB domain-containing protein 2(gene name synonym)|uniprotkb:Chromosome condensation 1-like(gene name synonym)|uniprotkb:RCC1-like G exchanging factor(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11528417|imex:IM-24995-634	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	refseq:NP_001259.1|refseq:NP_001273759.1|refseq:NP_001273760.1|refseq:NP_001273761.1|refseq:XP_005266299.1|refseq:XP_005266301.1|refseq:XP_006719822.1|ensembl:ENSG00000136161(gene)|ensembl:ENST00000344532(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR000408(Regulator of chromosome condensation, RCC1)|interpro:IPR009091(Regulator of chromosome condensation/beta-lactamase-inhibitor protein II)|interpro:IPR011333(BTB/POZ fold)|entrezgene/locuslink:1102(identity)	-	crc64:66699F37B0013088	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:VJjauSy5q9k4V5QceqoSYZQ5ep49606	intact-crc:2F297B96BF8EE562|rigid:AprCXFdpSyNS16xZwsp7R5S4ILk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38340	uniprotkb:O95198	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-746999|uniprotkb:B2RD18|uniprotkb:Q8N484|uniprotkb:Q8TBH5|uniprotkb:A6NCM7|uniprotkb:B4DFH7|uniprotkb:F5H6M3|ensembl:ENSP00000226725	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:klhl2_human(display_long)|uniprotkb:Actin-binding protein Mayven(gene name synonym)|uniprotkb:KLHL2(gene name)|psi-mi:KLHL2(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11528408|imex:IM-24995-633	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	refseq:NP_001154993.1|refseq:NP_001154994.1|refseq:NP_009177.3|refseq:NP_001317952.1|refseq:NP_001317953.1|refseq:XP_016863165.1|ensembl:ENSG00000109466(gene)|ensembl:ENST00000226725(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030027"(lamellipodium)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR017096(Kelch-like protein, gigaxonin)|interpro:IPR044072|mint:O95198|rcsb pdb:2XN4|rcsb pdb:4CHB|reactome:R-HSA-8951664|reactome:R-HSA-983168|go:"GO:0042802"(identical protein binding)|entrezgene/locuslink:11275(identity)	-	crc64:66699F37B0013088	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:tFegR2lJZccRqs4qUjdT3PNjNnk9606	intact-crc:CE559DA93D764234|rigid:lJxC0eiGxMGHHLeQdu8zDmVW8Ps	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O96006	uniprotkb:P38340	intact:EBI-740037|uniprotkb:Q96BY4|ensembl:ENSP00000370616|ensembl:ENSP00000370620|ensembl:ENSP00000370621|ensembl:ENSP00000498725	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:zbed1_human(display_long)|uniprotkb:ZBED1(gene name)|psi-mi:ZBED1(display_short)|uniprotkb:ALTE(gene name synonym)|uniprotkb:DREF(gene name synonym)|uniprotkb:KIAA0785(gene name synonym)|uniprotkb:TRAMP(gene name synonym)|uniprotkb:dREF homolog(gene name synonym)|uniprotkb:Putative Ac-like transposable element(gene name synonym)|uniprotkb:DNA replication-related element-binding factor(gene name synonym)|uniprotkb:Zinc finger BED domain-containing protein 1(gene name synonym)|uniprotkb:hDREF(gene name synonym)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11528426|imex:IM-24995-635	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164606.1|refseq:NP_001164607.1|refseq:NP_004720.1|ensembl:ENSG00000214717(gene)|ensembl:ENST00000381218(transcript)|ensembl:ENST00000381222(transcript)|ensembl:ENST00000381223(transcript)|ensembl:ENST00000652001(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0031965"(nuclear membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044828"(negative regulation by host of viral genome replication)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0061665"(SUMO ligase activity)|go:"GO:1990466"(protein autosumoylation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003656(Zinc finger, BED-type predicted)|interpro:IPR008906(HAT dimerisation)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR036236|mint:O96006|rcsb pdb:2CT5|reactome:R-HSA-4551638|go:"GO:0005813"(centrosome)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016605"(PML body)|entrezgene/locuslink:9189(identity)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	-	-	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:jl97ZV2Kz5YAmQKktWt/wk7OkRw9606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:98BE2CCB34ED603E|rigid:OsutfvhFYaGz8t3mj3RghBXI6Xw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38340	uniprotkb:P23511-2	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-11061759|ensembl:ENSP00000229418	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:p23511-2(display_long)|uniprotkb:NFYA(gene name)|psi-mi:NFYA(display_short)|uniprotkb:CAAT box DNA-binding protein subunit A(gene name synonym)|uniprotkb:Nuclear transcription factor Y subunit A(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11528509|imex:IM-24995-644	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	intact:EBI-389739(isoform-parent)|ensembl:ENSG00000001167(gene)|ensembl:ENST00000353205(transcript)|uniprotkb:P23511-2(isoform-parent)|entrezgene/locuslink:4800(identity)	-	crc64:66699F37B0013088	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:9IOUoaGszX6kd9hzrCj6BBkgJ+09606	intact-crc:DC168549C789968E|rigid:G3HyeGy+Y4dllNBePDME7Qpu6I8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38340	uniprotkb:P20591	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-929476|uniprotkb:D3DSI8|uniprotkb:B2RDA5|uniprotkb:B3KU10|uniprotkb:C9IYV7|uniprotkb:C9J8D6|uniprotkb:C9JN19|uniprotkb:C9JN88|uniprotkb:C9JUL1|uniprotkb:C9JZS6|uniprotkb:Q86YP5|uniprotkb:Q96CI3|ensembl:ENSP00000381599|ensembl:ENSP00000381601|ensembl:ENSP00000392151|ensembl:ENSP00000402215|ensembl:ENSP00000408498|ensembl:ENSP00000410523|ensembl:ENSP00000505029|ensembl:ENSP00000505047|ensembl:ENSP00000505051|ensembl:ENSP00000505189|ensembl:ENSP00000505457|ensembl:ENSP00000505489|ensembl:ENSP00000505630|ensembl:ENSP00000505657|ensembl:ENSP00000505669|ensembl:ENSP00000505781|ensembl:ENSP00000505874|ensembl:ENSP00000506047|ensembl:ENSP00000506062|ensembl:ENSP00000506183|ensembl:ENSP00000506199|ensembl:ENSP00000506220|ensembl:ENSP00000506270|ensembl:ENSP00000506348|ensembl:ENSP00000506372|ensembl:ENSP00000506395|ensembl:ENSP00000506481|ensembl:ENSP00000506512|ensembl:ENSP00000506690|ensembl:ENSP00000506712	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:mx1_human(display_long)|uniprotkb:MX1(gene name)|psi-mi:MX1(display_short)|uniprotkb:Myxovirus resistance protein 1(gene name synonym)|uniprotkb:Interferon-regulated resistance GTP-binding protein MxA(gene name synonym)|uniprotkb:Interferon-induced protein p78(gene name synonym)|uniprotkb:Myxoma resistance protein 1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11528500|imex:IM-24995-643	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	refseq:NP_001269849.1|refseq:NP_001138397.1|refseq:NP_001171517.1|refseq:NP_002453.2|refseq:XP_011527870.1|refseq:XP_005261037.1|refseq:XP_005261038.1|refseq:XP_005261039.1|refseq:XP_005261035.1|refseq:XP_005261036.1|refseq:XP_016883838.1|refseq:XP_016883839.1|dip:DIP-35694N|ensembl:ENSG00000157601(gene)|ensembl:ENST00000398598(transcript)|ensembl:ENST00000398600(transcript)|ensembl:ENST00000413778(transcript)|ensembl:ENST00000417963(transcript)|ensembl:ENST00000419044(transcript)|ensembl:ENST00000455164(transcript)|ensembl:ENST00000679445(transcript)|ensembl:ENST00000679464(transcript)|ensembl:ENST00000679543(transcript)|ensembl:ENST00000679626(transcript)|ensembl:ENST00000679705(transcript)|ensembl:ENST00000679911(transcript)|ensembl:ENST00000680176(transcript)|ensembl:ENST00000680182(transcript)|ensembl:ENST00000680347(transcript)|ensembl:ENST00000680364(transcript)|ensembl:ENST00000680536(transcript)|ensembl:ENST00000680629(transcript)|ensembl:ENST00000680760(transcript)|ensembl:ENST00000680776(transcript)|ensembl:ENST00000681039(transcript)|ensembl:ENST00000681191(transcript)|ensembl:ENST00000681266(transcript)|ensembl:ENST00000681415(transcript)|ensembl:ENST00000681607(transcript)|ensembl:ENST00000681671(transcript)|ensembl:ENST00000681849(transcript)|ensembl:ENST00000681857(transcript)|ensembl:ENST00000681867(transcript)|ensembl:ENST00000681896(transcript)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0003374"(dynamin family protein polymerization involved in mitochondrial fission)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0006952"(defense response)|go:"GO:0007165"(signal transduction)|go:"GO:0008017"(microtubule binding)|go:"GO:0009615"(response to virus)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016185"(synaptic vesicle budding from presynaptic endocytic zone membrane)|go:"GO:0030424"(axon)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031623"(receptor internalization)|go:"GO:0031965"(nuclear membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0034340"(response to type I interferon)|go:"GO:0042802"(identical protein binding)|go:"GO:0044327"(dendritic spine head)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0051607"(defense response to virus)|go:"GO:0061025"(membrane fusion)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:0098793"(presynapse)|go:"GO:0098844"(postsynaptic endocytic zone membrane)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:0140374"(antiviral innate immune response)|interpro:IPR000375(Dynamin central region)|interpro:IPR001401(Dynamin, GTPase region)|interpro:IPR003130(Dynamin GTPase effector)|interpro:IPR019762|interpro:IPR020850|interpro:IPR022812|interpro:IPR027417|interpro:IPR030381|mint:P20591|rcsb pdb:3LJB|rcsb pdb:3SZR|rcsb pdb:3ZYS|rcsb pdb:4P4S|rcsb pdb:4P4T|rcsb pdb:4P4U|rcsb pdb:5GTM|reactome:R-HSA-1169408|reactome:R-HSA-909733|entrezgene/locuslink:4599(identity)	-	crc64:66699F37B0013088	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:9rO7Zyl6v0Kq3xw6MKbVefk1hCA9606	intact-crc:F5DDA51168FB0E0C|rigid:2isHB41HHZLGGKSn1+EQx02KZHg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P15531	uniprotkb:P38340	intact:EBI-741141|ensembl:ENSP00000376892|uniprotkb:Q6FGK3|uniprotkb:Q86XQ2|uniprotkb:Q9UDJ6	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:ndka_human(display_long)|uniprotkb:Tumor metastatic process-associated protein(gene name synonym)|uniprotkb:Metastasis inhibition factor nm23(gene name synonym)|uniprotkb:Granzyme A-activated DNase(gene name synonym)|uniprotkb:NME1(gene name)|psi-mi:NME1(display_short)|uniprotkb:NDPKA(gene name synonym)|uniprotkb:NM23(gene name synonym)|uniprotkb:NM23-H1(gene name synonym)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11528491|imex:IM-24995-642	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000260.1|refseq:NP_937818.1|ensembl:ENSG00000239672(gene)|ensembl:ENST00000393196(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0002762"(negative regulation of myeloid leukocyte differentiation)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004536"(deoxyribonuclease activity)|go:"GO:0004550"(nucleoside diphosphate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0006183"(GTP biosynthetic process)|go:"GO:0006228"(UTP biosynthetic process)|go:"GO:0006241"(CTP biosynthetic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007595"(lactation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014075"(response to amine)|go:"GO:0016020"(membrane)|go:"GO:0019215"(intermediate filament binding)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051591"(response to cAMP)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071398"(cellular response to fatty acid)|interpro:IPR001564(Nucleoside diphosphate kinase, core)|go:"GO:0019899"(enzyme binding)|interpro:IPR023005|go:"GO:0021766"(hippocampus development)|interpro:IPR034907|interpro:IPR036850|mint:P15531|go:"GO:0030154"(cell differentiation)|go:"GO:0032587"(ruffle membrane)|rcsb pdb:1JXV|rcsb pdb:1UCN|go:"GO:0033574"(response to testosterone)|go:"GO:0035690"|rcsb pdb:2HVD|rcsb pdb:2HVE|rcsb pdb:3L7U|rcsb pdb:4ENO|rcsb pdb:5UI4|reactome:R-HSA-499943|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043024"(ribosomal small subunit binding)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|dip:DIP-39164N|entrezgene/locuslink:4830(identity)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	-	-	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Ut4gK1Xq786CaZzvqdS1eiU5op89606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:1360DCA1ADF66380|rigid:An9Y00CWrtenqHtdvGrjdLIdIfk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P07195	uniprotkb:P38340	intact:EBI-358748|ensembl:ENSP00000229319|ensembl:ENSP00000379386	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:ldhb_human(display_long)|uniprotkb:LDHB(gene name)|psi-mi:LDHB(display_short)|uniprotkb:LDH heart subunit(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-46(gene name synonym)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11528455|imex:IM-24995-638	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001167568.1|refseq:NP_002291.1|refseq:NP_001302466.1|ensembl:ENSG00000111716(gene)|ensembl:ENST00000350669(transcript)|ensembl:ENST00000396076(transcript)|go:"GO:0004459"(L-lactate dehydrogenase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0019752"(carboxylic acid metabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0045121"(membrane raft)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001236(Lactate/malate dehydrogenase)|interpro:IPR001557(L-lactate/malate dehydrogenase)|interpro:IPR011304(L-lactate dehydrogenase)|interpro:IPR015955(Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal)|interpro:IPR018177|interpro:IPR022383|interpro:IPR036291|mint:P07195|rcsb pdb:1I0Z|rcsb pdb:1T2F|reactome:R-HSA-70268|entrezgene/locuslink:3945(identity)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	-	-	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:umdj6fjSO7+4SM9Hrl1/K2EiKls9606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:D145A2AD915BC457|rigid:u8nJ3fWsXWTbmmVX+FV2vOEmMDQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38340	uniprotkb:P07910-2	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-5280084|ensembl:ENSP00000442816|ensembl:ENSP00000450544|ensembl:ENSP00000450725|ensembl:ENSP00000451176	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:p07910-2(display_long)|uniprotkb:HNRNPC(gene name)|psi-mi:HNRNPC(display_short)|uniprotkb:HNRPC(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11528473|imex:IM-24995-640	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	uniprotkb:P07910-2(isoform-parent)|intact:EBI-357966(isoform-parent)|ensembl:ENSG00000092199(gene)|ensembl:ENST00000430246(transcript)|ensembl:ENST00000553300(transcript)|ensembl:ENST00000554969(transcript)|ensembl:ENST00000556897(transcript)|entrezgene/locuslink:3183(identity)	-	crc64:66699F37B0013088	isoform-comment:Contains a phosphoserine at position 107. Contains a phosphoserine at position 108.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:r7AhGozE3aHdynLr8DrXPRtOuyI9606	intact-crc:90465B6B44D485F7|rigid:/IqKzh8jrl3ECXJ1Fx+WsR4iX6M	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38340	uniprotkb:P07910	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-357966|uniprotkb:P22628|uniprotkb:Q53EX2|uniprotkb:Q59FD3|uniprotkb:Q5FWE8|uniprotkb:Q86SF8|uniprotkb:Q86U45|uniprotkb:Q96HK7|uniprotkb:Q96HM4|uniprotkb:Q96IY5|uniprotkb:Q9BTS3|uniprotkb:D3DS19|uniprotkb:D3DS22|intact:EBI-28976506|ensembl:ENSP00000404848|ensembl:ENSP00000451291|ensembl:ENSP00000452276	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:hnrpc_human(display_long)|uniprotkb:HNRNPC(gene name)|psi-mi:HNRNPC(display_short)|uniprotkb:HNRPC(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11528464|imex:IM-24995-639	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	refseq:NP_001070910.1|refseq:NP_001070911.1|refseq:NP_004491.2|refseq:NP_112604.2|ensembl:ENSP00000404848|ensembl:ENST00000430246|ensembl:ENSP00000442816|ensembl:ENST00000553300|ensembl:ENSP00000450544|ensembl:ENSP00000451291|ensembl:ENST00000554969|ensembl:ENSP00000452276|ensembl:ENSP00000450725|ensembl:ENST00000555883|ensembl:ENSP00000450629|ensembl:ENST00000556628|ensembl:ENSP00000451652|ensembl:ENST00000556897|ensembl:ENSP00000451176|refseq:XP_011535010.1|refseq:XP_011535011.1|refseq:XP_011535012.1|refseq:XP_011535013.1|refseq:XP_011535014.1|refseq:XP_016876741.1|refseq:XP_016876742.1|dip:DIP-29854N|refseq:XP_006720188.1|ensembl:ENSG00000092199(gene)|ensembl:ENST00000420743(transcript)|ensembl:ENST00000554455(transcript)|ensembl:ENST00000557201(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000785"(chromatin)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005829"(cytosol)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0008380"(RNA splicing)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043044"|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070935"(3'-UTR-mediated mRNA stabilization)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990247"(N6-methyladenosine-containing RNA binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR017347(Heterogeneous nuclear ribonucleoprotein C, Raly)|interpro:IPR035979|mint:P07910|rcsb pdb:1TXP|rcsb pdb:1WF2|rcsb pdb:2MXY|rcsb pdb:2MZ1|rcsb pdb:3LN4|reactome:R-HSA-4570464|reactome:R-HSA-72163|reactome:R-HSA-72203|reactome:R-HSA-9013418|reactome:R-HSA-9013422|entrezgene/locuslink:3183(identity)	-	crc64:66699F37B0013088	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:Fj5tiH0wrNUjTnsURIg8dB8laMg9606	intact-crc:BCF3BDD2C4F796E2|rigid:/dGmj8DEWCpiwUdODoXbKQWMeJI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P12268	uniprotkb:P38340	intact:EBI-353389|uniprotkb:Q6LEF3|ensembl:ENSP00000321584	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:imdh2_human(display_long)|uniprotkb:IMPDH2(gene name)|psi-mi:IMPDH2(display_short)|uniprotkb:IMPD2(gene name synonym)|uniprotkb:Inosine-5'-monophosphate dehydrogenase type II(gene name synonym)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11528482|imex:IM-24995-641	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000875.2|ensembl:ENSG00000178035(gene)|ensembl:ENST00000326739(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003938"(IMP dehydrogenase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006177"(GMP biosynthetic process)|go:"GO:0006183"(GTP biosynthetic process)|go:"GO:0007623"(circadian rhythm)|go:"GO:0016020"(membrane)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042802"(identical protein binding)|go:"GO:0046651"(lymphocyte proliferation)|go:"GO:0046872"(metal ion binding)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR001093(IMP dehydrogenase/GMP reductase)|interpro:IPR005990(IMP dehydrogenase)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR015875(IMP dehydrogenase / GMP reductase, conserved site)|mint:P12268|rcsb pdb:1B3O|rcsb pdb:1NF7|rcsb pdb:1NFB|rcsb pdb:6I0M|rcsb pdb:6I0O|rcsb pdb:6U8E|rcsb pdb:6U8N|rcsb pdb:6U8R|rcsb pdb:6U8S|rcsb pdb:6U9O|rcsb pdb:6UA2|rcsb pdb:6UA4|rcsb pdb:6UA5|rcsb pdb:6UAJ|rcsb pdb:6UC2|rcsb pdb:6UDO|rcsb pdb:6UDP|rcsb pdb:6UDQ|reactome:R-HSA-6798695|reactome:R-HSA-73817|reactome:R-HSA-9679191|entrezgene/locuslink:3615(identity)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	-	-	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:qGPwBxhEgtYik3OetHZbpyktoLE9606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:8D09FD124BB41B3C|rigid:tdNFZkQsBnNk6qxyY9zk21jBHGA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38340	uniprotkb:P49247	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-744831|uniprotkb:Q541P9|uniprotkb:Q96BJ6|ensembl:ENSP00000283646	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:rpia_human(display_long)|uniprotkb:Phosphoriboisomerase(gene name synonym)|uniprotkb:RPIA(gene name)|psi-mi:RPIA(display_short)|uniprotkb:RPI(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11528564|imex:IM-24995-650	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	refseq:NP_653164.2|ensembl:ENSG00000153574(gene)|ensembl:ENST00000283646(transcript)|go:"GO:0004751"(ribose-5-phosphate isomerase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006014"(D-ribose metabolic process)|go:"GO:0006098"(pentose-phosphate shunt)|go:"GO:0009052"(pentose-phosphate shunt, non-oxidative branch)|go:"GO:0019693"(ribose phosphate metabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048029"(monosaccharide binding)|interpro:IPR004788(Ribose 5-phosphate isomerase)|interpro:IPR020672|interpro:IPR037171|mint:P49247|reactome:R-HSA-5659996|reactome:R-HSA-6791461|reactome:R-HSA-71336|entrezgene/locuslink:22934(identity)	-	crc64:66699F37B0013088	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:gddu0Xp/dx4JwbFMs50pQCvvbws9606	intact-crc:7A28771CF84EBBCC|rigid:N5V4GvqknWvyrUhzlVV65DEhyfw	false	-	sufficient binding region:75-311	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48775	uniprotkb:P38340	intact:EBI-743494|ensembl:ENSP00000444788|ensembl:ENSP00000460086|uniprotkb:A8K053	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:t23o_human(display_long)|uniprotkb:Tryptophan pyrrolase(gene name synonym)|uniprotkb:Tryptophan oxygenase(gene name synonym)|uniprotkb:Tryptamin 2,3-dioxygenase(gene name synonym)|uniprotkb:TDO2(gene name)|psi-mi:TDO2(display_short)|uniprotkb:TDO(gene name synonym)|uniprotkb:Tryptophanase(gene name synonym)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11528555|imex:IM-24995-649	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000151790(gene)|ensembl:ENSG00000262635(gene)|ensembl:ENST00000536354(transcript)|ensembl:ENST00000573403(transcript)|go:"GO:0004833"(tryptophan 2,3-dioxygenase activity)|go:"GO:0005829"(cytosol)|go:"GO:0016597"(amino acid binding)|go:"GO:0019441"(tryptophan catabolic process to kynurenine)|go:"GO:0019442"(tryptophan catabolic process to acetyl-CoA)|go:"GO:0019825"(oxygen binding)|go:"GO:0020037"(heme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051289"(protein homotetramerization)|go:"GO:1904842"(response to nitroglycerin)|interpro:IPR004981(Tryptophan 2,3-dioxygenase)|interpro:IPR037217|mint:P48775|rcsb pdb:4PW8|rcsb pdb:5TI9|rcsb pdb:5TIA|rcsb pdb:6A4I|rcsb pdb:6PYY|rcsb pdb:6PYZ|rcsb pdb:6UD5|rcsb pdb:6VBN|reactome:R-HSA-71240|refseq:NP_005642.1|entrezgene/locuslink:6999(identity)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	-	-	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:S+cyc710I52nIFQWgKhXFul9QZw9606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:4CD534AC1654C3E2|rigid:0jJMO8ij0i4soToT9UC7lpFwQVI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P35520	uniprotkb:P38340	intact:EBI-740135|uniprotkb:Q99425|uniprotkb:Q9BWC5|uniprotkb:B2R993|uniprotkb:D3DSK4|intact:EBI-14245939|ensembl:ENSP00000344460|ensembl:ENSP00000352643|ensembl:ENSP00000381225|ensembl:ENSP00000381231	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:cbs_human(display_long)|uniprotkb:CBS(gene name)|psi-mi:CBS(display_short)|uniprotkb:Serine sulfhydrase(gene name synonym)|uniprotkb:Beta-thionase(gene name synonym)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11528518|imex:IM-24995-645	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000062.1|refseq:NP_001171479.1|refseq:NP_001171480.1|ensembl:ENSG00000160200(gene)|ensembl:ENST00000352178(transcript)|ensembl:ENST00000359624(transcript)|ensembl:ENST00000398158(transcript)|go:"GO:0004122"(cystathionine beta-synthase activity)|ensembl:ENST00000398165(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006535"(cysteine biosynthetic process from serine)|go:"GO:0006563"(L-serine metabolic process)|go:"GO:0006565"(L-serine catabolic process)|go:"GO:0019343"(cysteine biosynthetic process via cystathionine)|go:"GO:0019344"(cysteine biosynthetic process)|go:"GO:0019346"(transsulfuration)|go:"GO:0019448"(L-cysteine catabolic process)|go:"GO:0019825"(oxygen binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0020037"(heme binding)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042262"(DNA protection)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043418"(homocysteine catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0050421"("nitrite reductase (NO-forming) activity")|go:"GO:0050667"(homocysteine metabolic process)|go:"GO:0070025"(carbon monoxide binding)|go:"GO:0070026"(nitric oxide binding)|go:"GO:0070814"(hydrogen sulfide biosynthetic process)|go:"GO:0072341"(modified amino acid binding)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR001216(Cysteine synthase/cystathionine beta-synthase P-phosphate-binding site)|interpro:IPR001926(Pyridoxal phosphate-dependent enzyme, beta subunit)|interpro:IPR005857(Cystathionine beta-synthase)|interpro:IPR036052|mint:P35520|rcsb pdb:1JBQ|rcsb pdb:1M54|rcsb pdb:4COO|rcsb pdb:4L0D|rcsb pdb:4L27|rcsb pdb:4L28|rcsb pdb:4L3V|rcsb pdb:4PCU|rcsb pdb:4UUU|rcsb pdb:5MMS|reactome:R-HSA-1614603|reactome:R-HSA-2408508|refseq:XP_011528079.1|refseq:XP_011528083.1|refseq:XP_011528084.1|refseq:XP_011544396.1|refseq:XP_011544397.1|refseq:XP_011544399.1|refseq:XP_011544400.1|refseq:XP_011544401.1|refseq:NP_001307227.1|refseq:NP_001308002.1|refseq:XP_016883700.1|refseq:XP_016883701.1|refseq:XP_016883702.1|refseq:XP_016883703.1|refseq:XP_016883704.1|refseq:XP_016883705.1|refseq:XP_016883706.1|refseq:XP_016883707.1|refseq:XP_016883978.1|refseq:XP_016883979.1|refseq:XP_016883980.1|refseq:XP_016883981.1|entrezgene/locuslink:875(identity)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	-	-	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:f9eo0cPOHppVY7Nqejag3YyK18s9606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:3D3F1080375CDBB2|rigid:UctRQejoRQJyfKCSH+eIvdt/Fx0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38432	uniprotkb:P38340	intact:EBI-945751|uniprotkb:B2R931|ensembl:ENSP00000240316	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:coil_human(display_long)|uniprotkb:COIL(gene name)|psi-mi:COIL(display_short)|uniprotkb:CLN80(gene name synonym)|uniprotkb:p80-coilin(gene name synonym)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11528537|imex:IM-24995-647	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004636.1|dip:DIP-38503N|ensembl:ENSG00000121058(gene)|ensembl:ENST00000240316(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0015030"(Cajal body)|go:"GO:0016020"(membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0030619"(U1 snRNA binding)|go:"GO:0030620"(U2 snRNA binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR024822|interpro:IPR031722|mint:P38432|entrezgene/locuslink:8161(identity)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	-	-	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:hd5p6AbyA/GYNEeca99Mdb41qM09606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:57F0D0EEB500F8F5|rigid:LampXM0o/TLDnA7/30h35Wyu4V4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38340	uniprotkb:P38159	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-743526|ensembl:ENSP00000359645|uniprotkb:Q5JQ67|uniprotkb:Q969R3|uniprotkb:D3DWH0|uniprotkb:E9PG86|uniprotkb:Q8N8Y7|uniprotkb:B4E3U4	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:rbmx_human(display_long)|uniprotkb:Glycoprotein p43(gene name synonym)|uniprotkb:RBMX(gene name)|psi-mi:RBMX(display_short)|uniprotkb:HNRPG(gene name synonym)|uniprotkb:RBMXP1(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein G(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11528528|imex:IM-24995-646	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	ensembl:ENSG00000147274(gene)|ensembl:ENST00000320676(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000791"(euchromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0044530"(supraspliceosomal complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0006509"(membrane protein ectodomain proteolysis)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012604(RBM1CTR)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|mint:P38159|rcsb pdb:2MB0|rcsb pdb:2MKS|reactome:R-HSA-72163|reactome:R-HSA-72203|reactome:R-HSA-9013418|reactome:R-HSA-9013422|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273|refseq:NP_002130.2|refseq:NP_001158275.1|dip:DIP-34447N|entrezgene/locuslink:27316(identity)	-	crc64:66699F37B0013088	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:ocCkdy9PxjeVLUQf0tMVCEhFfO89606	intact-crc:BA21662C8363E54C|rigid:Lr3MO6Jzc9pvQFInXgb84MSkeJ8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38340	uniprotkb:P38646	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-354932|ensembl:ENSP00000297185|uniprotkb:P30036|uniprotkb:P31932|uniprotkb:Q6GU03|uniprotkb:Q9BWB7|uniprotkb:B2RCM1|uniprotkb:Q1HB43|uniprotkb:Q53H23|uniprotkb:Q9UC56	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:grp75_human(display_long)|uniprotkb:HSPA9(gene name)|psi-mi:HSPA9(display_short)|uniprotkb:GRP75(gene name synonym)|uniprotkb:HSPA9B(gene name synonym)|uniprotkb:75 kDa glucose-regulated protein(gene name synonym)|uniprotkb:Heat shock 70 kDa protein 9(gene name synonym)|uniprotkb:Peptide-binding protein 74(gene name synonym)|uniprotkb:Mortalin(gene name synonym)|uniprotkb:mt-HSP70(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11528546|imex:IM-24995-648	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	reactome:R-HSA-8949613|reactome:R-HSA-8950505|ensembl:ENSG00000113013(gene)|ensembl:ENST00000297185(transcript)|go:"GO:0001401"(SAM complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005925"(focal adhesion)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0007007"(inner mitochondrial membrane organization)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045646"(regulation of erythrocyte differentiation)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0140275"(MIB complex)|go:"GO:1902037"(negative regulation of hematopoietic stem cell differentiation)|go:"GO:1903707"(negative regulation of hemopoiesis)|interpro:IPR012725(Chaperone DnaK)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|go:"GO:0070062"(extracellular exosome)|interpro:IPR043129|mint:P38646|rcsb pdb:3N8E|rcsb pdb:4KBO|rcsb pdb:6NHK|rcsb pdb:6P2U|rcsb pdb:6PMT|reactome:R-HSA-1268020|reactome:R-HSA-3371453|refseq:NP_004125.3|dip:DIP-32936N|entrezgene/locuslink:3313(identity)	-	crc64:66699F37B0013088	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:xjSHeTKBb/lH1XNEEiMIjsM+XcE9606	intact-crc:EEB7091B11403367|rigid:pM5gDg0qNFxvRHzy6g57D7kSfCw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38340	uniprotkb:P63279	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11528622|imex:IM-24995-656	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N|entrezgene/locuslink:7329(identity)	-	crc64:66699F37B0013088	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	intact-crc:5030B1EC8E9A2F60|rigid:yPWLvTo5VQGN2yAOaM1tPNCnHvg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38340	uniprotkb:P63261	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-351292|uniprotkb:P02571|uniprotkb:P14104|uniprotkb:P99022|uniprotkb:Q5U032|uniprotkb:Q96E67|uniprotkb:A8K7C2|ensembl:ENSP00000505060|ensembl:ENSP00000505193|ensembl:ENSP00000505235|ensembl:ENSP00000506126|ensembl:ENSP00000506201|ensembl:ENSP00000506253|ensembl:ENSP00000458162|ensembl:ENSP00000458435|ensembl:ENSP00000459119|ensembl:ENSP00000459124|ensembl:ENSP00000460464|ensembl:ENSP00000460660|ensembl:ENSP00000461672|ensembl:ENSP00000466346|ensembl:ENSP00000477968	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:actg_human(display_long)|uniprotkb:ACTG1(gene name)|psi-mi:ACTG1(display_short)|uniprotkb:ACTG(gene name synonym)|uniprotkb:Gamma-actin(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11528612|imex:IM-24995-655	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	refseq:NP_001186883.1|refseq:NP_001605.1|ensembl:ENST00000570382(transcript)|ensembl:ENSG00000184009(gene)|ensembl:ENST00000571721(transcript)|ensembl:ENST00000573283(transcript)|ensembl:ENST00000575087(transcript)|ensembl:ENST00000575659(transcript)|ensembl:ENST00000575842(transcript)|ensembl:ENST00000575994(transcript)|ensembl:ENST00000576544(transcript)|ensembl:ENST00000615544(transcript)|ensembl:ENST00000679480(transcript)|ensembl:ENST00000679778(transcript)|ensembl:ENST00000680227(transcript)|ensembl:ENST00000680727(transcript)|ensembl:ENST00000681052(transcript)|ensembl:ENST00000681842(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0001895"(retina homeostasis)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005522"(profilin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0030016"(myofibril)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031941"(filamentous actin)|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0044305"(calyx of Held)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0051492"(regulation of stress fiber assembly)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070527"(platelet aggregation)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0072562"(blood microparticle)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0097433"(dense body)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098973"(structural constituent of postsynaptic actin cytoskeleton)|go:"GO:0120192"(tight junction assembly)|go:"GO:0120220"(basal body patch)|go:"GO:0150111"(regulation of transepithelial transport)|go:"GO:1902396"(protein localization to bicellular tight junction)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P63261|rcsb pdb:5JLH|rcsb pdb:6CXI|rcsb pdb:6CXJ|rcsb pdb:6G2T|rcsb pdb:6V62|rcsb pdb:6V63|rcsb pdb:6WK1|rcsb pdb:6WK2|reactome:R-HSA-1445148|reactome:R-HSA-190873|reactome:R-HSA-196025|reactome:R-HSA-2029482|reactome:R-HSA-3928662|reactome:R-HSA-3928665|reactome:R-HSA-418990|reactome:R-HSA-437239|reactome:R-HSA-4420097|reactome:R-HSA-445095|reactome:R-HSA-446353|reactome:R-HSA-5626467|reactome:R-HSA-5663213|reactome:R-HSA-5663220|reactome:R-HSA-5674135|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8856828|reactome:R-HSA-9013418|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9662360|reactome:R-HSA-9662361|reactome:R-HSA-9664422|entrezgene/locuslink:71(identity)	-	crc64:66699F37B0013088	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:B2OOsE06lTfo90H3g8tlmUJQ7cY9606	intact-crc:7CB7475442EAF74E|rigid:MnDFBVJYjyHANBw0C0Mv5JYfEM0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P60709	uniprotkb:P38340	intact:EBI-353944|uniprotkb:P02570|uniprotkb:P70514|uniprotkb:P99021|uniprotkb:Q11211|uniprotkb:Q64316|uniprotkb:Q75MN2|uniprotkb:Q96B34|uniprotkb:Q96HG5|ensembl:ENSP00000494269|ensembl:ENSP00000494750|ensembl:ENSP00000495995|ensembl:ENSP00000501862|ensembl:ENSP00000502821	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:actb_human(display_long)|uniprotkb:ACTB(gene name)|psi-mi:ACTB(display_short)|uniprotkb:Beta-actin(gene name synonym)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11528575|imex:IM-24995-651	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001092.1|ensembl:ENSG00000075624(gene)|ensembl:ENST00000493945(transcript)|ensembl:ENST00000642480(transcript)|ensembl:ENST00000646664(transcript)|ensembl:ENST00000674681(transcript)|ensembl:ENST00000675515(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000785"(chromatin)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0001895"(retina homeostasis)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007409"(axonogenesis)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019894"(kinesin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0022898"(regulation of transmembrane transporter activity)|go:"GO:0030027"(lamellipodium)|go:"GO:0030424"(axon)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0030957"(Tat protein binding)|go:"GO:0031982"(vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034333"(adherens junction assembly)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043044"|go:"GO:0043296"(apical junction complex)|go:"GO:0044305"(calyx of Held)|go:"GO:0045176"(apical protein localization)|go:"GO:0045202"(synapse)|go:"GO:0048156"(tau protein binding)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048870"(cell motility)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051621"(regulation of norepinephrine uptake)|go:"GO:0051623"(positive regulation of norepinephrine uptake)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070160"(tight junction)|go:"GO:0070527"(platelet aggregation)|reactome:R-HSA-4420097|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0072562"(blood microparticle)|go:"GO:0072749"(cellular response to cytochalasin B)|go:"GO:0097433"(dense body)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098973"(structural constituent of postsynaptic actin cytoskeleton)|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0150111"(regulation of transepithelial transport)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P60709|rcsb pdb:3BYH|rcsb pdb:3D2U|rcsb pdb:3J82|rcsb pdb:3LUE|rcsb pdb:6ANU|rcsb pdb:6ICT|rcsb pdb:6ICV|rcsb pdb:6LTJ|rcsb pdb:6MBJ|rcsb pdb:6MBK|rcsb pdb:6MBL|rcsb pdb:6NBW|rcsb pdb:6OX0|rcsb pdb:6OX1|rcsb pdb:6OX2|rcsb pdb:6OX3|rcsb pdb:6OX4|rcsb pdb:6OX5|rcsb pdb:6V62|rcsb pdb:6V63|rcsb pdb:6WK1|rcsb pdb:6WK2|rcsb pdb:7AS4|reactome:R-HSA-1445148|reactome:R-HSA-190873|reactome:R-HSA-196025|reactome:R-HSA-2029482|reactome:R-HSA-3214847|reactome:R-HSA-389957|reactome:R-HSA-390450|reactome:R-HSA-3928662|reactome:R-HSA-3928665|reactome:R-HSA-418990|reactome:R-HSA-437239|reactome:R-HSA-446353|reactome:R-HSA-5250924|reactome:R-HSA-5626467|reactome:R-HSA-5663213|reactome:R-HSA-5663220|reactome:R-HSA-5674135|reactome:R-HSA-5689603|reactome:R-HSA-5696394|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8856828|reactome:R-HSA-9035034|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9662360|reactome:R-HSA-9662361|reactome:R-HSA-9664422|reactome:R-HSA-983231|reactome:R-HSA-445095|dip:DIP-29686N|entrezgene/locuslink:60(identity)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	-	-	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Hoge1B8Pn56kvbNTpkSLsQuHwRc9606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:854A4B898BE58A49|rigid:dOsk2RtACj0gTuWtoa2+2MORKdE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38340	uniprotkb:P61289	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-355546|uniprotkb:O35563|uniprotkb:P97373|uniprotkb:Q12920|uniprotkb:Q13172|uniprotkb:Q9BQD9|uniprotkb:A8K9A3|ensembl:ENSP00000466794	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:psme3_human(display_long)|uniprotkb:PSME3(gene name)|psi-mi:PSME3(display_short)|uniprotkb:Proteasome activator 28 subunit gamma(gene name synonym)|uniprotkb:Activator of multicatalytic protease subunit 3(gene name synonym)|uniprotkb:11S regulator complex subunit gamma(gene name synonym)|uniprotkb:Ki nuclear autoantigen(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11528594|imex:IM-24995-653	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	refseq:NP_005780.2|refseq:NP_789839.1|ensembl:ENSG00000131467(gene)|ensembl:ENST00000590720(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0008537"(proteasome activator complex)|go:"GO:0010950"(positive regulation of endopeptidase activity)|go:"GO:0016020"(membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0061133"(endopeptidase activator activity)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0097371"(MDM2/MDM4 family protein binding)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR003185(Proteasome activator pa28, REG alpha subunit)|interpro:IPR003186(Proteasome activator pa28, REG beta subunit)|interpro:IPR009077(Proteasome activator pa28, REG alpha/beta subunit)|interpro:IPR036252|interpro:IPR036996|interpro:IPR036997|mint:P61289|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|entrezgene/locuslink:10197(identity)	-	crc64:66699F37B0013088	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:6EQY2Kj3Juf++m4eBDzPWMgbC2k9606	intact-crc:D212783F0579995F|rigid:7U4wu5I6Bsc+tS2OG9Fyn5XNSG8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P60891	uniprotkb:P38340	intact:EBI-749195|uniprotkb:P09329|uniprotkb:B2R6T7|uniprotkb:B1ALA8|uniprotkb:B4DNL6|uniprotkb:D3DUX6|ensembl:ENSP00000361512	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:prps1_human(display_long)|uniprotkb:Phosphoribosyl pyrophosphate synthase I(gene name synonym)|uniprotkb:PRPS1(gene name)|psi-mi:PRPS1(display_short)|uniprotkb:PPRibP(gene name synonym)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11528585|imex:IM-24995-652	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001191331.1|refseq:NP_002755.1|ensembl:ENSG00000147224(gene)|ensembl:ENST00000372435(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0002189"(ribose phosphate diphosphokinase complex)|go:"GO:0004749"(ribose phosphate diphosphokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006015"(5-phosphoribose 1-diphosphate biosynthetic process)|go:"GO:0006164"(purine nucleotide biosynthetic process)|go:"GO:0006221"(pyrimidine nucleotide biosynthetic process)|go:"GO:0007399"(nervous system development)|go:"GO:0009116"(nucleoside metabolic process)|go:"GO:0009156"(ribonucleoside monophosphate biosynthetic process)|go:"GO:0016301"(kinase activity)|go:"GO:0034418"(urate biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046101"(hypoxanthine biosynthetic process)|interpro:IPR000836(Phosphoribosyltransferase)|interpro:IPR000842(Phosphoribosyl pyrophosphate synthetase, conserved site)|interpro:IPR005946(Phosphoribosyl pyrophosphokinase)|go:"GO:0006144"(purine nucleobase metabolic process)|interpro:IPR029057|interpro:IPR029099|interpro:IPR037515|rcsb pdb:2H06|rcsb pdb:2H07|rcsb pdb:2H08|rcsb pdb:2HCR|rcsb pdb:3EFH|rcsb pdb:3S5J|rcsb pdb:4F8E|rcsb pdb:4LYG|rcsb pdb:4LZN|rcsb pdb:4LZO|rcsb pdb:4M0P|rcsb pdb:4M0U|reactome:R-HSA-73843|dip:DIP-61999N|entrezgene/locuslink:5631(identity)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	-	-	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:+Hih2M7JLTsjEglauBlPj182h9M9606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:1409C79A54C8C4DC|rigid:EEjOnv8wbKDeIzNK2fZ28hS+xLw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38340	uniprotkb:P62333	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-357669|uniprotkb:Q92524|uniprotkb:P49719|uniprotkb:Q6IBU3|uniprotkb:B2R975|ensembl:ENSP00000401802	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:prs10_human(display_long)|uniprotkb:PSMC6(gene name)|psi-mi:PSMC6(display_short)|uniprotkb:SUG2(gene name synonym)|uniprotkb:Proteasome 26S subunit ATPase 6(gene name synonym)|uniprotkb:Proteasome subunit p42(gene name synonym)|uniprotkb:26S proteasome AAA-ATPase subunit RPT4(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11528603|imex:IM-24995-654	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	refseq:NP_002797.3|ensembl:ENST00000445930(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|ensembl:ENSG00000100519(gene)|go:"GO:0005829"(cytosol)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0016234"(inclusion body)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0042802"(identical protein binding)|interpro:IPR032501|interpro:IPR035263|interpro:IPR041569|mint:P62333|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHJ|rcsb pdb:5VHM|rcsb pdb:5VHN|rcsb pdb:5VHO|rcsb pdb:5VHP|rcsb pdb:5VHQ|rcsb pdb:5VHR|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090261"(positive regulation of inclusion body assembly)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-75815|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-174184|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|dip:DIP-38150N|entrezgene/locuslink:5706(identity)	-	crc64:66699F37B0013088	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:QE8jzSEp1bpzhOi/oAAnV18QK249606	intact-crc:FB24B56FBA253333|rigid:pDcOS7AIb75qNpuh4qYhVztcmHI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q13867	uniprotkb:P38340	intact:EBI-718504|uniprotkb:Q53F86|uniprotkb:Q9UER9|uniprotkb:B2R796|ensembl:ENSP00000261714	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:blmh_human(display_long)|uniprotkb:BLMH(gene name)|psi-mi:BLMH(display_short)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11528678|imex:IM-24995-662	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000377.1|ensembl:ENSG00000108578(gene)|ensembl:ENST00000261714(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004177"(aminopeptidase activity)|go:"GO:0004180"(carboxypeptidase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006508"(proteolysis)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0009636"(response to toxic substance)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043418"(homocysteine catabolic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000169(Peptidase, cysteine peptidase active site)|interpro:IPR004134(Peptidase C1B, bleomycin hydrolase)|interpro:IPR038765|mint:Q13867|rcsb pdb:1CB5|rcsb pdb:2CB5|reactome:R-HSA-983168|entrezgene/locuslink:642(identity)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	-	-	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:THDv63DC81eQzFvmyWs1rlCBMyk9606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:92E088258F922AAD|rigid:yUwNVOPo80ORo/HA36C+4GlHasM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38340	uniprotkb:Q13155	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-745226|uniprotkb:Q75MR1|uniprotkb:Q96CZ5|uniprotkb:Q9P1L2|ensembl:ENSP00000223029|uniprotkb:F8W950	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:aimp2_human(display_long)|uniprotkb:Protein JTV-1(gene name synonym)|uniprotkb:AIMP2(gene name)|psi-mi:AIMP2(display_short)|uniprotkb:PRO0992(orf name)|uniprotkb:JTV1(gene name synonym)|uniprotkb:Multisynthase complex auxiliary component p38(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11528668|imex:IM-24995-661	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	refseq:NP_006294.2|ensembl:ENSG00000106305(gene)|ensembl:ENST00000223029(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0006915"(apoptotic process)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0017101"(aminoacyl-tRNA synthetase multienzyme complex)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060510"(type II pneumocyte differentiation)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1903632"(positive regulation of aminoacyl-tRNA ligase activity)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR031889|interpro:IPR036282|interpro:IPR041503|interpro:IPR042360|mint:Q13155|rcsb pdb:4DPG|rcsb pdb:4YCU|rcsb pdb:4YCW|rcsb pdb:5A1N|rcsb pdb:5A34|rcsb pdb:5A5H|rcsb pdb:5Y6L|rcsb pdb:6ILD|rcsb pdb:6IY6|rcsb pdb:6JPV|rcsb pdb:6K39|reactome:R-HSA-2408522|reactome:R-HSA-379716|dip:DIP-34421N|refseq:NP_001313536.1|entrezgene/locuslink:7965(identity)	-	crc64:66699F37B0013088	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:VEBmJjo6t3dBY6mKpmUyVLamJFQ9606	intact-crc:2979026FBC179719|rigid:jR+RbnhnSRFmhMPqtcFqWwRSkMw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38340	uniprotkb:P98170	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-517127|uniprotkb:Q9NQ14|uniprotkb:D3DTF2|ensembl:ENSP00000347858|ensembl:ENSP00000360242|ensembl:ENSP00000395230	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:xiap_human(display_long)|uniprotkb:Inhibitor of apoptosis protein 3(gene name synonym)|uniprotkb:X-linked inhibitor of apoptosis protein(gene name synonym)|uniprotkb:IAP-like protein(gene name synonym)|uniprotkb:XIAP(gene name)|psi-mi:XIAP(display_short)|uniprotkb:API3(gene name synonym)|uniprotkb:IAP3(gene name synonym)|uniprotkb:BIRC4(gene name synonym)|uniprotkb:Baculoviral IAP repeat-containing protein 4(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase XIAP(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11528631|imex:IM-24995-657	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	refseq:XP_006724817.1|refseq:NP_001158.2|refseq:NP_001191330.1|refseq:XP_011529631.1|dip:DIP-27626N|ensembl:ENSG00000101966(gene)|ensembl:ENST00000355640(transcript)|ensembl:ENST00000371199(transcript)|ensembl:ENST00000434753(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005876"(spindle microtubule)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030510"(regulation of BMP signaling pathway)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0055070"(copper ion homeostasis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070424"(regulation of nucleotide-binding oligomerization domain containing signaling pathway)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:1902530"(positive regulation of protein linear polyubiquitination)|go:"GO:1990001"(inhibition of cysteine-type endopeptidase activity involved in apoptotic process)|interpro:IPR001370(Proteinase inhibitor I32, inhibitor of apoptosis)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011029(DEATH-like)|interpro:IPR042579|mint:P98170|rcsb pdb:1C9Q|rcsb pdb:1F9X|rcsb pdb:1G3F|rcsb pdb:1G73|rcsb pdb:1I3O|rcsb pdb:1I4O|rcsb pdb:1I51|rcsb pdb:1KMC|rcsb pdb:1NW9|rcsb pdb:1TFQ|rcsb pdb:1TFT|rcsb pdb:2ECG|rcsb pdb:2JK7|rcsb pdb:2KNA|rcsb pdb:2OPY|rcsb pdb:2OPZ|rcsb pdb:2POI|rcsb pdb:2POP|rcsb pdb:2QRA|rcsb pdb:2VSL|rcsb pdb:3CLX|rcsb pdb:3CM2|rcsb pdb:3CM7|rcsb pdb:3EYL|rcsb pdb:3G76|rcsb pdb:3HL5|rcsb pdb:3UW4|rcsb pdb:3UW5|rcsb pdb:4EC4|rcsb pdb:4HY0|rcsb pdb:4IC2|rcsb pdb:4IC3|rcsb pdb:4J3Y|rcsb pdb:4J44|rcsb pdb:4J45|rcsb pdb:4J46|rcsb pdb:4J47|rcsb pdb:4J48|rcsb pdb:4KJU|rcsb pdb:4KJV|rcsb pdb:4KMP|rcsb pdb:4MTZ|rcsb pdb:4OXC|rcsb pdb:4WVS|rcsb pdb:4WVT|rcsb pdb:4WVU|rcsb pdb:5C0K|rcsb pdb:5C0L|rcsb pdb:5C3H|rcsb pdb:5C3K|rcsb pdb:5C7A|rcsb pdb:5C7B|rcsb pdb:5C7C|rcsb pdb:5C7D|rcsb pdb:5C83|rcsb pdb:5C84|rcsb pdb:5M6E|rcsb pdb:5M6F|rcsb pdb:5M6H|rcsb pdb:5M6L|rcsb pdb:5M6M|rcsb pdb:5O6T|rcsb pdb:5OQW|rcsb pdb:6EY2|rcsb pdb:6GJW|rcsb pdb:6QCI|reactome:R-HSA-111459|reactome:R-HSA-111463|reactome:R-HSA-111464|reactome:R-HSA-111469|reactome:R-HSA-3769402|reactome:R-HSA-5213460|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5675482|reactome:R-HSA-8948747|reactome:R-HSA-8948751|reactome:R-HSA-9627069|entrezgene/locuslink:331(identity)	-	crc64:66699F37B0013088	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:6eDcOay+c2ZmIAD/pwnCDROBwgM9606	intact-crc:F5B8F77B5456E73A|rigid:hKpSWqBZNFklBmgvmQu7TjwTT2Y	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38340	uniprotkb:Q12800	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-717422|uniprotkb:Q12801|uniprotkb:Q9UD77|uniprotkb:A8K5E9|uniprotkb:Q9UD75|ensembl:ENSP00000257915	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:tfcp2_human(display_long)|uniprotkb:Transcription factor LSF(gene name synonym)|uniprotkb:SAA3 enhancer factor(gene name synonym)|uniprotkb:TFCP2(gene name)|psi-mi:TFCP2(display_short)|uniprotkb:LSF(gene name synonym)|uniprotkb:SEF(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11528650|imex:IM-24995-659	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	refseq:NP_001166923.1|refseq:NP_001166924.1|refseq:NP_005644.2|ensembl:ENSG00000135457(gene)|ensembl:ENST00000257915(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR007604(CP2 transcription factor)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR037599|interpro:IPR041418|mint:Q12800|entrezgene/locuslink:7024(identity)	-	crc64:66699F37B0013088	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:M7mQ08NDYxuawmUEKRgjSdIr+Og9606	intact-crc:7638925174C13986|rigid:yH67WZVVVPUmvnYbu6oMf54oRps	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38340	uniprotkb:Q03393	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-712344|ensembl:ENSP00000280362|uniprotkb:Q8WVG8|uniprotkb:B0YJ87	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:ptps_human(display_long)|uniprotkb:PTS(gene name)|psi-mi:PTS(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11528640|imex:IM-24995-658	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	refseq:NP_000308.1|ensembl:ENSG00000150787(gene)|ensembl:ENST00000280362(transcript)|go:"GO:0003874"(6-pyruvoyltetrahydropterin synthase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006520"(cellular amino acid metabolic process)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0007417"(central nervous system development)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR007115(6-pyruvoyl tetrahydropterin synthase-related)|interpro:IPR022469|interpro:IPR022470|interpro:IPR038418|rcsb pdb:3I2B|reactome:R-HSA-1474151|entrezgene/locuslink:5805(identity)	-	crc64:66699F37B0013088	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:Qa3bMpzyvRxrvDq9dZUSQlfbpeg9606	intact-crc:F4879293C7BD830A|rigid:/B45h0c5qBVDxEyJmefaim2Nfjw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38340	uniprotkb:Q13049	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-742790|ensembl:ENSP00000363095|ensembl:ENSP00000408292|uniprotkb:Q9NQP8	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:tri32_human(display_long)|uniprotkb:Zinc finger protein HT2A(gene name synonym)|uniprotkb:72 kDa Tat-interacting protein(gene name synonym)|uniprotkb:TRIM32(gene name)|psi-mi:TRIM32(display_short)|uniprotkb:HT2A(gene name synonym)|uniprotkb:Tripartite motif-containing protein 32(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM32(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11528659|imex:IM-24995-660	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	go:"GO:0043621"(protein self-association)|go:"GO:0045087"(innate immune response)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051155"(positive regulation of striated muscle cell differentiation)|go:"GO:0061564"(axon development)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1902187"|go:"GO:1902230"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:1903265"(positive regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:1903883"(positive regulation of interleukin-17-mediated signaling pathway)|go:"GO:1903886"("positive regulation of chemokine (C-C motif) ligand 20 production")|go:"GO:2000147"(positive regulation of cell motility)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENSG00000119401(gene)|ensembl:ENST00000373983(transcript)|ensembl:ENST00000450136(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001894"(tissue homeostasis)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005863"(striated muscle myosin thick filament)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007014"(actin ubiquitination)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009411"(response to UV)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0017022"(myosin binding)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030957"(Tat protein binding)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034612"(response to tumor necrosis factor)|go:"GO:0042802"(identical protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|interpro:IPR000315(Zinc finger, B-box)|refseq:NP_001093149.1|refseq:XP_011516700.1|refseq:NP_036342.2|refseq:XP_005251870.1|interpro:IPR001258(NHL repeat)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR013017(NHL repeat, subgroup)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR027370|mint:Q13049|rcsb pdb:2CT2|rcsb pdb:5FEY|reactome:R-HSA-3134975|reactome:R-HSA-983168|refseq:XP_016869975.1|entrezgene/locuslink:22954(identity)	-	crc64:66699F37B0013088	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:XuqprQd10kSpsuyGs+FSdzIdJ/Y9606	intact-crc:3EC16F0FB6A9F542|rigid:wrjCZrkmckE2GdnFZY8FI/59o0U	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q16637	uniprotkb:P38340	intact:EBI-395421|uniprotkb:Q13119|uniprotkb:Q549U5|uniprotkb:Q96J51|ensembl:ENSP00000305857|uniprotkb:A8K0V4|ensembl:ENSP00000370083|ensembl:ENSP00000370117|ensembl:ENSP00000370119|ensembl:ENSP00000479920|ensembl:ENSP00000482966|ensembl:ENSP00000483515|ensembl:ENSP00000483819|ensembl:ENSP00000487206|ensembl:ENSP00000487421	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:smn_human(display_long)|uniprotkb:SMN1(gene name)|psi-mi:SMN1(display_short)|uniprotkb:SMN(gene name synonym)|uniprotkb:SMNT(gene name synonym)|uniprotkb:SMN2(gene name)|psi-mi:SMN2(display_short)|uniprotkb:SMNC(gene name synonym)|uniprotkb:Component of gems 1(gene name synonym)|uniprotkb:Gemin-1(gene name synonym)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11528733|imex:IM-24995-668	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000335.1|refseq:NP_059107.1|refseq:NP_075012.1|refseq:NP_075013.1|refseq:NP_075014.1|refseq:NP_075015.1|ensembl:ENSG00000172062(gene)|ensembl:ENSG00000205571(gene)|ensembl:ENSG00000273772(gene)|ensembl:ENSG00000275349(gene)|ensembl:ENSG00000277773(gene)|ensembl:ENST00000351205(transcript)|ensembl:ENST00000380707(transcript)|ensembl:ENST00000380741(transcript)|ensembl:ENST00000380743(transcript)|ensembl:ENST00000614610(transcript)|ensembl:ENST00000618251(transcript)|ensembl:ENST00000618661(transcript)|ensembl:ENST00000622739(transcript)|ensembl:ENST00000627341(transcript)|ensembl:ENST00000629122(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0007399"(nervous system development)|go:"GO:0015030"(Cajal body)|go:"GO:0016604"(nuclear body)|go:"GO:0030018"(Z disc)|go:"GO:0030424"(axon)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043204"(perikaryon)|go:"GO:0097504"(Gemini of coiled bodies)|interpro:IPR002999(Tudor)|interpro:IPR010304(Survival motor neuron)|mint:Q16637|rcsb pdb:1G5V|rcsb pdb:1MHN|rcsb pdb:2LEH|rcsb pdb:4A4E|rcsb pdb:4A4G|rcsb pdb:4GLI|rcsb pdb:4QQ6|rcsb pdb:5XJL|go:"GO:0034719"(SMN-Sm protein complex)|rcsb pdb:5XJQ|rcsb pdb:5XJR|rcsb pdb:5XJS|rcsb pdb:5XJT|rcsb pdb:5XJU|reactome:R-HSA-191859|go:"GO:0032797"(SMN complex)|refseq:NP_001284644.1|ensembl:ENSP00000305857|ensembl:ENSP00000370083|ensembl:ENSP00000370117|ensembl:ENST00000380742|ensembl:ENSP00000370118|ensembl:ENSP00000370119|ensembl:ENST00000503079|ensembl:ENSP00000428128|ensembl:ENST00000506163|ensembl:ENSP00000424926|ensembl:ENST00000611442|ensembl:ENSP00000483768|ensembl:ENST00000614240|ensembl:ENSP00000479279|ensembl:ENSP00000479920|ensembl:ENST00000614773|ensembl:ENSP00000481427|ensembl:ENSP00000483515|ensembl:ENSP00000483819|ensembl:ENST00000622158|ensembl:ENSP00000480906|ensembl:ENSP00000482966|ensembl:ENST00000624634|ensembl:ENSP00000485595|ensembl:ENST00000626847|ensembl:ENSP00000486152|ensembl:ENSP00000487421|ensembl:ENST00000628353|ensembl:ENSP00000487029|ensembl:ENST00000628642|ensembl:ENSP00000487015|ensembl:ENSP00000487206|refseq:XP_016865275.1|dip:DIP-31309N|entrezgene/locuslink:6607(identity)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	-	-	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:QGivm7E8suciCWXO4l0zCUzCl2g9606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:E1FFB00F89049671|rigid:Kq/4LIJwTNVmItvsCg9v0/vIhBM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38340	uniprotkb:Q15427	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-348469|ensembl:ENSP00000271628|intact:EBI-1047735|uniprotkb:Q5SZ63	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:sf3b4_human(display_long)|uniprotkb:SF3B4(gene name)|psi-mi:SF3B4(display_short)|uniprotkb:SAP49(gene name synonym)|uniprotkb:Spliceosome-associated protein 49(gene name synonym)|uniprotkb:Pre-mRNA-splicing factor SF3b 49 kDa subunit(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11528724|imex:IM-24995-667	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	refseq:NP_005841.1|ensembl:ENSG00000143368(gene)|ensembl:ENST00000271628(transcript)|rcsb pdb:6QX9|rcsb pdb:6Y53|rcsb pdb:6Y5Q|rcsb pdb:7ABG|rcsb pdb:7ABH|rcsb pdb:7ABI|rcsb pdb:7DVQ|reactome:R-HSA-72163|reactome:R-HSA-72165|rcsb pdb:6AHD|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:1990935"(splicing factor binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034158|go:"GO:0000375"(RNA splicing, via transesterification reactions)|interpro:IPR034159|interpro:IPR035979|mint:Q15427|rcsb pdb:1X5T|rcsb pdb:5GVQ|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|entrezgene/locuslink:10262(identity)	-	crc64:66699F37B0013088	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:Jgy6WmBFKkphpZLLte2GgsagUVI9606	intact-crc:577959A702C1E307|rigid:3VKOeIx9t1GaLwUpa67IqPqIbOA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38340	uniprotkb:Q14749	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-744239|uniprotkb:Q9NNZ1|uniprotkb:Q9NS24|uniprotkb:Q5T8W2|ensembl:ENSP00000361894	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:gnmt_human(display_long)|uniprotkb:GNMT(gene name)|psi-mi:GNMT(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11528687|imex:IM-24995-663	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	refseq:NP_061833.1|refseq:NP_001305794.1|ensembl:ENSG00000124713(gene)|ensembl:ENST00000372808(transcript)|go:"GO:0005542"(folic acid binding)|go:"GO:0005829"(cytosol)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0006111"(regulation of gluconeogenesis)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006555"(methionine metabolic process)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0016594"(glycine binding)|go:"GO:0017174"(glycine N-methyltransferase activity)|go:"GO:0032259"(methylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0046498"(S-adenosylhomocysteine metabolic process)|go:"GO:0046500"(S-adenosylmethionine metabolic process)|go:"GO:0051289"(protein homotetramerization)|go:"GO:1901052"(sarcosine metabolic process)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|interpro:IPR014369(Glycine N-methyltransferase)|interpro:IPR029063|interpro:IPR041698|rcsb pdb:1R74|rcsb pdb:2AZT|reactome:R-HSA-2408508|reactome:R-HSA-389661|entrezgene/locuslink:27232(identity)	-	crc64:66699F37B0013088	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:noj0nCgjJ1Dq079ycrwAu30a4AU9606	intact-crc:E1C4E2C6ED5EDDBE|rigid:c92KjjiBa0Gz8YncPU5yIUfJv7M	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38340	uniprotkb:Q15038	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-724310|ensembl:ENSP00000394699|uniprotkb:E9PB45|uniprotkb:A8K254|uniprotkb:B4DDT5|uniprotkb:C9JA96|uniprotkb:C9JP84|uniprotkb:B4E1G3|uniprotkb:F8VU62	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:dazp2_human(display_long)|uniprotkb:Deleted in azoospermia-associated protein 2(gene name synonym)|uniprotkb:DAZAP2(gene name)|psi-mi:DAZAP2(display_short)|uniprotkb:KIAA0058(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11528706|imex:IM-24995-665	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	ensembl:ENSG00000183283(gene)|ensembl:ENST00000412716(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0016607"(nuclear speck)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0050699"(WW domain binding)|interpro:IPR022730|mint:Q15038|refseq:NP_001129736.1|refseq:NP_055579.1|ensembl:ENSP00000394699|ensembl:ENST00000425012|ensembl:ENSP00000408251|ensembl:ENST00000439799|ensembl:ENSP00000398804|ensembl:ENST00000449723|ensembl:ENSP00000412812|ensembl:ENST00000549555|ensembl:ENSP00000448051|ensembl:ENST00000549732|ensembl:ENSP00000446554|refseq:NP_001129741.1|refseq:NP_001129739.1|refseq:NP_001129740.1|refseq:NP_001129738.1|entrezgene/locuslink:9802(identity)	-	crc64:66699F37B0013088	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:ASRqCZBG4q1U/y95PUSMKsgfm/g9606	intact-crc:5F8317E400FB7D25|rigid:tWYfZtkHuwaAtyHJIKpEo2Z9YTY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q15025	uniprotkb:P38340	intact:EBI-357849|uniprotkb:A4F1W8|uniprotkb:O76008|uniprotkb:Q96EL9|uniprotkb:Q99833|uniprotkb:Q9H1J3|uniprotkb:B7Z699|uniprotkb:Q6N077|ensembl:ENSP00000317891|ensembl:ENSP00000428187|ensembl:ENSP00000430760|uniprotkb:A4F1W9|uniprotkb:A4F1X2|uniprotkb:A4F1X4|uniprotkb:A4F1X5|uniprotkb:A4F1X6|uniprotkb:A4F1X7|uniprotkb:A4F1X9|uniprotkb:E7EPY1|uniprotkb:E7ET96|uniprotkb:Q05KP3|uniprotkb:Q05KP4	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:tnip1_human(display_long)|uniprotkb:TNIP1(gene name)|psi-mi:TNIP1(display_short)|uniprotkb:KIAA0113(gene name synonym)|uniprotkb:NAF1(gene name synonym)|uniprotkb:Nef-associated factor 1(gene name synonym)|uniprotkb:HIV-1 Nef-interacting protein(gene name synonym)|uniprotkb:Virion-associated nuclear shuttling protein(gene name synonym)|uniprotkb:Nip40-1(gene name synonym)|uniprotkb:A20-binding inhibitor of NF-kappa-B activation 1(gene name synonym)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11528696|imex:IM-24995-664	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006049.3|refseq:NP_001239319.1|refseq:NP_001239320.1|refseq:NP_001239321.1|refseq:NP_001239322.1|refseq:NP_001245383.1|dip:DIP-27577N|refseq:NP_001239315.1|ensembl:ENSG00000145901(gene)|ensembl:ENST00000315050(transcript)|ensembl:ENST00000521591(transcript)|ensembl:ENST00000522226(transcript)|go:"GO:0002755"(MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0006952"(defense response)|go:"GO:0006954"(inflammatory response)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0009101"(glycoprotein biosynthetic process)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0085032"(modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade)|go:"GO:1903003"(positive regulation of protein deubiquitination)|interpro:IPR033372|mint:Q15025|reactome:R-HSA-5689896|go:"GO:0051019"(mitogen-activated protein kinase binding)|refseq:NP_001239314.1|refseq:NP_001245384.1|refseq:NP_001245385.1|refseq:XP_006714814.1|refseq:XP_006714815.1|entrezgene/locuslink:10318(identity)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	-	-	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:16Vjb5CuGTAbW2M22qbCxgXtV1o9606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:9A6C316DE43C3003|rigid:SBHyqjq5wE+LbLMQbXVnKqxweoo	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q15415	uniprotkb:P38340	intact:EBI-8642021|uniprotkb:B2R916|intact:MINT-8163253|ensembl:ENSP00000250831|ensembl:ENSP00000307155	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:rby1f_human(display_long)|uniprotkb:RBMY1F(gene name)|psi-mi:RBMY1F(display_short)|uniprotkb:RBMY1J(gene name)|psi-mi:RBMY1J(display_short)|uniprotkb:Y chromosome RNA recognition motif 2(gene name synonym)|uniprotkb:YRRM2(gene name synonym)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11528715|imex:IM-24995-666	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001290339.1|refseq:NP_001006117.2|refseq:NP_689798.1|ensembl:ENSG00000169800(gene)|ensembl:ENSG00000226941(gene)|ensembl:ENST00000250831(transcript)|ensembl:ENST00000303766(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016607"(nuclear speck)|go:"GO:0042802"(identical protein binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012604(RBM1CTR)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|entrezgene/locuslink:159163(identity)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	-	comment:mint	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:lEyv+LmtOFRifaC5g6jDlh5WCnM9606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:813BA95AF8EB0D4D|rigid:wQHrJT0tIFinJYuQMAAo3VWix+M	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38340	uniprotkb:Q6RW13-2	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-11522760|ensembl:ENSP00000365816	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:q6rw13-2(display_long)|uniprotkb:AGTRAP(gene name)|psi-mi:AGTRAP(display_short)|uniprotkb:AT1 receptor-associated protein(gene name synonym)|uniprotkb:ATRAP(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11528787|imex:IM-24995-674	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	ensembl:ENSG00000177674(gene)|ensembl:ENST00000376629(transcript)|intact:EBI-741181(isoform-parent)|uniprotkb:Q6RW13-2(isoform-parent)|entrezgene/locuslink:57085(identity)	-	crc64:66699F37B0013088	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:PNzVis/8puQZBJ562gCqZKc078s9606	intact-crc:2AB16055166419BD|rigid:A+Xt1mCM+n7/uS0ETA2CRRNAvNY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q5VWX1	uniprotkb:P38340	intact:EBI-742808|uniprotkb:Q8TCZ4|uniprotkb:Q8N4I4|uniprotkb:A8K7M8|ensembl:ENSP00000281156	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:khdr2_human(display_long)|uniprotkb:SLM1(gene name synonym)|uniprotkb:Sam68-like mammalian protein 1(gene name synonym)|uniprotkb:KHDRBS2(gene name)|psi-mi:KHDRBS2(display_short)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11528778|imex:IM-24995-673	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_689901.2|ensembl:ENSG00000112232(gene)|ensembl:ENST00000281156(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008143"("poly(A) binding")|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0017124"(SH3 domain binding)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR032335|interpro:IPR032571|interpro:IPR036612|reactome:R-HSA-8849468|entrezgene/locuslink:202559(identity)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	-	-	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:IfFvZO2dIAo0Sdx+BUb5c8F7aQY9606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:B6E232EE8207BD39|rigid:0T4js7J5FoPVuVYAEbM1jIc36Ic	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38340	uniprotkb:Q16637-3	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-395447|ensembl:ENSP00000424926|ensembl:ENSP00000486152|ensembl:ENSP00000487015|ensembl:ENSP00000487029|intact:EBI-8628183|intact:MINT-95595	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:q16637-3(display_long)|uniprotkb:Iso7-SMN(isoform synonym)|uniprotkb:SMN1(gene name)|psi-mi:SMN1(display_short)|uniprotkb:SMN2(gene name)|psi-mi:SMN2(display_short)|uniprotkb:SMN(gene name synonym)|uniprotkb:SMNT(gene name synonym)|uniprotkb:SMNC(gene name synonym)|uniprotkb:Component of gems 1(gene name synonym)|uniprotkb:Gemin-1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11528742|imex:IM-24995-669	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	intact:EBI-395421(smn_human)|ensembl:ENSG00000275349(gene)|ensembl:ENST00000506163(transcript)|ensembl:ENST00000626847(transcript)|ensembl:ENST00000628353(transcript)|ensembl:ENST00000628642(transcript)|ensembl:ENSG00000172062(gene)|ensembl:ENSG00000205571(gene)|ensembl:ENSG00000273772(gene)|uniprotkb:Q16637-3(isoform-parent)|entrezgene/locuslink:6607(identity)	-	crc64:66699F37B0013088	isoform-comment:Thought to be a non-functional protein that lacks the capacity to oligomerize and thus cannot interact with Sm proteins. Primarily derived from SMN2 gene.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:ICA63eidVxJ219M+YZJ20zNh+xU9606	intact-crc:E79C7F694A0552C7|rigid:wu48ZQpwfDqQm7Y7vGLoNyQek4Q	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38340	uniprotkb:Q5JST6	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-2349927|uniprotkb:Q9H653|uniprotkb:Q5JST8|uniprotkb:Q68DK4|uniprotkb:Q8NEI0|intact:EBI-28971886|ensembl:ENSP00000404232	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:efhc2_human(display_long)|uniprotkb:EFHC2(gene name)|psi-mi:EFHC2(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11528760|imex:IM-24995-671	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	ensembl:ENSP00000404232|refseq:NP_079460.2|ensembl:ENSG00000183690(gene)|ensembl:ENST00000420999(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005930"(axoneme)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0060285"(cilium-dependent cell motility)|go:"GO:0072686"(mitotic spindle)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR006602(Region of unknown function DM10)|interpro:IPR011992(EF-Hand type)|interpro:IPR040193|rcsb pdb:2Z13|rcsb pdb:2Z14|entrezgene/locuslink:80258(identity)	-	crc64:66699F37B0013088	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:O1XriQSkLcYkk7H7AlanQ1FKIBY9606	intact-crc:0DE3E9F528C0CDAE|rigid:sbi4qDEg3OEUgfzrgQnqO7aHA24	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q53EZ4	uniprotkb:P38340	intact:EBI-747776|uniprotkb:Q32WF5|uniprotkb:Q3MV20|uniprotkb:Q5VY28|uniprotkb:Q6N034|ensembl:ENSP00000360540|uniprotkb:Q96H32|uniprotkb:Q9NVS7|uniprotkb:B2RDG8|intact:EBI-10173536|uniprotkb:D3DR37|intact:EBI-28973801	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:cep55_human(display_long)|uniprotkb:Up-regulated in colon cancer 6(gene name synonym)|uniprotkb:CEP55(gene name)|psi-mi:CEP55(display_short)|uniprotkb:URCC6(gene name synonym)|uniprotkb:C10orf3(gene name synonym)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11528751|imex:IM-24995-670	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001120654.1|refseq:NP_060601.3|ensembl:ENSG00000138180(gene)|ensembl:ENST00000371485(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0014066"(regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0030496"(midbody)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042802"(identical protein binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0061952"(midbody abscission)|go:"GO:0090543"(Flemming body)|go:"GO:1904888"(cranial skeletal system development)|interpro:IPR022008|interpro:IPR038926|mint:Q53EZ4|rcsb pdb:3E1R|rcsb pdb:3WUT|rcsb pdb:3WUU|rcsb pdb:3WUV|go:"GO:0005814"(centriole)|ensembl:ENSP00000360540|dip:DIP-44581N|entrezgene/locuslink:55165(identity)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	-	-	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:tuo36vVb8ZgPDR81YjZFNEg559w9606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:72D867CDFC2C4D3F|rigid:dnMfuhgSQScUNIvPg2emyYRhpSc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38340	uniprotkb:Q5T124-6	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-11524408	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:q5t124-6(display_long)|uniprotkb:UBXN11(gene name)|psi-mi:UBXN11(display_short)|uniprotkb:Colorectal tumor-associated antigen COA-1(gene name synonym)|uniprotkb:SOC(gene name synonym)|uniprotkb:Socius(gene name synonym)|uniprotkb:UBX domain-containing protein 5(gene name synonym)|uniprotkb:UBXD5(gene name synonym)|uniprotkb:PP2243(orf name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11528769|imex:IM-24995-672	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	intact:EBI-746004(isoform-parent)|uniprotkb:Q5T124-6(isoform-parent)|entrezgene/locuslink:91544(identity)	-	crc64:66699F37B0013088	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:1YSjG/p2ihcjl4P8KdPCaX2HxiY9606	intact-crc:900BA8AE1C2A8789|rigid:mJIZimAvyqKNqPRmPVlcNf+vq5E	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38340	uniprotkb:Q8IXK0-5	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-11527347|ensembl:ENSP00000507877	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:q8ixk0-5(display_long)|uniprotkb:EDR2(gene name synonym)|uniprotkb:Early development regulatory protein 2(gene name synonym)|uniprotkb:PH2(gene name synonym)|uniprotkb:PHC2(gene name)|psi-mi:PHC2(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11528826|imex:IM-24995-678	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	ensembl:ENSG00000134686(gene)|ensembl:ENST00000683057(transcript)|intact:EBI-713786(isoform-parent)|uniprotkb:Q8IXK0-5(isoform-parent)|entrezgene/locuslink:1912(identity)	-	crc64:66699F37B0013088	isoform-comment:No experimental confirmation available.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:bkZ10pedX8mCMrcppjyd4tl7hm09606	intact-crc:BC6363D59108E182|rigid:UK282+UTG2MbTh7PNk4WAupJt0w	false	-	sufficient binding region:537-859	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38340	uniprotkb:Q86UW9	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-740376|uniprotkb:Q96H69|uniprotkb:Q9H890|uniprotkb:Q9P200|uniprotkb:Q6XM88|ensembl:ENSP00000322885|ensembl:ENSP00000390218|ensembl:ENSP00000411986|uniprotkb:Q6XM87|intact:EBI-10192429|uniprotkb:Q4ZH49	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:dtx2_human(display_long)|uniprotkb:RING finger protein 58(gene name synonym)|uniprotkb:DTX2(gene name)|psi-mi:DTX2(display_short)|uniprotkb:KIAA1528(gene name synonym)|uniprotkb:RNF58(gene name synonym)|uniprotkb:Protein deltex-2(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase DTX2(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11528796|imex:IM-24995-675	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	refseq:NP_001096064.1|refseq:NP_001096065.1|refseq:NP_001096066.1|refseq:NP_065943.2|ensembl:ENSP00000322885|ensembl:ENSP00000390218|ensembl:ENSP00000411986|ensembl:ENST00000446820|ensembl:ENSP00000392545|ensembl:ENSG00000091073(gene)|ensembl:ENST00000324432(transcript)|ensembl:ENST00000413936(transcript)|ensembl:ENST00000430490(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031965"(nuclear membrane)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR004170(WWE)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR018123|interpro:IPR018957|interpro:IPR037197|interpro:IPR039396|interpro:IPR039398|interpro:IPR039399|mint:Q86UW9|rcsb pdb:6IR0|rcsb pdb:6Y22|rcsb pdb:6Y2X|rcsb pdb:6Y3J|reactome:R-HSA-2122948|refseq:XP_011514074.1|refseq:XP_011514075.1|refseq:XP_011514076.1|refseq:XP_011514077.1|refseq:XP_005250188.1|refseq:XP_005250189.1|refseq:XP_016867212.1|refseq:XP_016867213.1|refseq:XP_016867214.1|refseq:XP_016867215.1|refseq:XP_016867216.1|entrezgene/locuslink:113878(identity)	-	crc64:66699F37B0013088	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:ugnjqAbG6Ekyc8MGugCnjc9zVaI9606	intact-crc:FD3D403435736C47|rigid:1Ha/wQdxNX3u33uinTzJuwTQHR4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q86WT6-2	uniprotkb:P38340	intact:EBI-11525489|ensembl:ENSP00000342922|ensembl:ENSP00000479720	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:q86wt6-2(display_long)|uniprotkb:RING-type E3 ubiquitin transferase TRIM69(gene name synonym)|uniprotkb:TRIM69(gene name)|psi-mi:TRIM69(display_short)|uniprotkb:RFP-like domain-containing protein trimless(gene name synonym)|uniprotkb:RING finger protein 36(gene name synonym)|uniprotkb:RNF36(gene name synonym)|uniprotkb:Tripartite motif-containing protein 69(gene name synonym)|uniprotkb:HSD-34(orf name)|uniprotkb:HSD34(orf name)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11528806|imex:IM-24995-676	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-749955(isoform-parent)|uniprotkb:Q86WT6-2(isoform-parent)|ensembl:ENSG00000185880(gene)|ensembl:ENSG00000278211(gene)|ensembl:ENST00000338264(transcript)|ensembl:ENST00000618398(transcript)|entrezgene/locuslink:140691(identity)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	-	-	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:J0mzn4PSX5vWZqt4X3Ee1Wxx5hw9606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:FC74AC7BB03E2BC8|rigid:rYUx2nVbzRHViiZnnNUPEFxMCpA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8IUQ4-2	uniprotkb:P38340	intact:EBI-11522811|ensembl:ENSP00000349156	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:q8iuq4-2(display_long)|uniprotkb:SIAH1(gene name)|psi-mi:SIAH1(display_short)|uniprotkb:HUMSIAH(gene name synonym)|uniprotkb:Seven in absentia homolog 1(gene name synonym)|uniprotkb:Siah-1a(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase SIAH1(gene name synonym)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11528815|imex:IM-24995-677	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-747107(isoform-parent)|ensembl:ENSG00000196470(gene)|ensembl:ENST00000356721(transcript)|uniprotkb:Q8IUQ4-2(isoform-parent)|entrezgene/locuslink:6477(identity)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	-	-	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:M4q06jVbWuq1mGMXvtuFBaMEgZM9606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:8ACDD7EE5C2F755E|rigid:0el1JYLTyDSSh/VBenuQxdsjgiE	false	sufficient binding region:32-313	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38340	uniprotkb:Q8NHQ1	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-739624|ensembl:ENSP00000264982|ensembl:ENSP00000419231|uniprotkb:Q96B31|uniprotkb:Q9H2C3|uniprotkb:Q9H2Z1|uniprotkb:Q9H940|uniprotkb:D3DNE9|uniprotkb:B7Z5I8|uniprotkb:B7Z7E8|uniprotkb:F5GZX8	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:cep70_human(display_long)|uniprotkb:CEP70(gene name)|psi-mi:CEP70(display_short)|uniprotkb:BITE(gene name synonym)|uniprotkb:p10-binding protein(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11528879|imex:IM-24995-683	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	ensembl:ENSG00000114107(gene)|ensembl:ENST00000264982(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|interpro:IPR019734|interpro:IPR037692|mint:Q8NHQ1|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|ensembl:ENST00000484888(transcript)|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_077817.2|refseq:XP_016862764.1|refseq:NP_001275893.1|refseq:NP_001275894.1|refseq:NP_001275895.1|refseq:NP_001275896.1|refseq:NP_001307527.1|refseq:NP_001307529.1|entrezgene/locuslink:80321(identity)	-	crc64:66699F37B0013088	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:S4yveQWcvdVtAUX65gqrJ5Dv0Mc9606	intact-crc:5E71B91D9F63D28A|rigid:tp1An3X6liuUeZd/ZN9x5Ms1p3M	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38340	uniprotkb:Q8NDC0	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-741424|uniprotkb:Q96BG5|ensembl:ENSP00000378851|ensembl:ENSP00000481882|uniprotkb:B2RDD8	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:missl_human(display_long)|uniprotkb:C14orf32(gene name synonym)|uniprotkb:Mitogen-activated protein kinase 1-interacting protein 1-like(gene name synonym)|uniprotkb:MAPK1IP1L(gene name)|psi-mi:MAPK1IP1L(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11528870|imex:IM-24995-682	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	refseq:NP_653179.1|ensembl:ENSG00000168175(gene)|ensembl:ENST00000395468(transcript)|ensembl:ENST00000622254(transcript)|interpro:IPR031653|entrezgene/locuslink:93487(identity)	-	crc64:66699F37B0013088	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:CX220vB2TjggPEso5CHNUVzl79g9606	intact-crc:33A3615B9B67DD15|rigid:WWegKoQBJiuvFiywqiCXJStd3AI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8NA61-2	uniprotkb:P38340	intact:EBI-11524851|ensembl:ENSP00000368249|ensembl:ENSP00000480148	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:q8na61-2(display_long)|uniprotkb:CBY2(gene name)|psi-mi:CBY2(display_short)|uniprotkb:SPERT(gene name synonym)|uniprotkb:Spermatid-associated protein(gene name synonym)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11528861|imex:IM-24995-681	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-741724(isoform-parent)|ensembl:ENSG00000174015(gene)|ensembl:ENST00000378966(transcript)|ensembl:ENST00000610924(transcript)|uniprotkb:Q8NA61-2(isoform-parent)|entrezgene/locuslink:220082(identity)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	-	-	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:SogYcXGGMYRYzB9xKC5o0pEtsDs9606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:32CCF6CD24D323A7|rigid:NhAM0HIjA6aSDU1k4mqFLCknSvI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8N6K7-2	uniprotkb:P38340	intact:EBI-11528848|ensembl:ENSP00000324874	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:q8n6k7-2(display_long)|uniprotkb:SAMD3(gene name)|psi-mi:SAMD3(display_short)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11528852|imex:IM-24995-680	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-748741(isoform-parent)|ensembl:ENSG00000164483(gene)|ensembl:ENST00000324172(transcript)|uniprotkb:Q8N6K7-2(isoform-parent)|entrezgene/locuslink:154075(identity)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	-	isoform-comment:No experimental confirmation available.	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:2ZsHFOFMqw/yebw24QlvgpYFVso9606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:32CB12FEB9033D3D|rigid:bEcj5U8qypoTMCNPiWZwGC6WGYY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8N0S2	uniprotkb:P38340	intact:EBI-6872807|ensembl:ENSP00000341282|uniprotkb:Q9BWU4|uniprotkb:B2RC80|uniprotkb:Q9BWU3	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:syce1_human(display_long)|uniprotkb:C10orf94(gene name synonym)|uniprotkb:Cancer/testis antigen 76(gene name synonym)|uniprotkb:SYCE1(gene name)|psi-mi:SYCE1(display_short)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11528837|imex:IM-24995-679	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000171772(gene)|ensembl:ENST00000343131(transcript)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0000801"(central element)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051301"(cell division)|interpro:IPR026676|reactome:R-HSA-1221632|refseq:NP_001137235.1|refseq:NP_570140.1|entrezgene/locuslink:93426(identity)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	-	-	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:qLVqIlFiwZJHFfoyYXV3jrqdd609606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:40064F29E1042DCD|rigid:D4In7CizkteBP9/zVwBSbM0sqmA	false	sufficient binding region:37-351	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q969F0	uniprotkb:P38340	intact:EBI-743099|ensembl:ENSP00000359375	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:fate1_human(display_long)|uniprotkb:Tumor antigen BJ-HCC-2(gene name synonym)|uniprotkb:Cancer/testis antigen 43(gene name synonym)|uniprotkb:FATE1(gene name)|psi-mi:FATE1(display_short)|uniprotkb:FATE(gene name synonym)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11528937|imex:IM-24995-689	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_149076.1|ensembl:ENSG00000147378(gene)|ensembl:ENST00000370350(transcript)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|go:"GO:0051562"(negative regulation of mitochondrial calcium ion concentration)|interpro:IPR039153|interpro:IPR039433|mint:Q969F0|entrezgene/locuslink:89885(identity)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	-	-	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Nm1N6lO92MHr5rIKC007oouF5RE9606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:D6AC1389D72269FA|rigid:/+zc1OuYwsGDsNuo4mQd/iw7VIE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q93062-3	uniprotkb:P38340	intact:EBI-740343|ensembl:ENSP00000340176	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:q93062-3(display_long)|uniprotkb:RBPMS(gene name)|psi-mi:RBPMS(display_short)|uniprotkb:HERMES(gene name synonym)|uniprotkb:Heart and RRM expressed sequence(gene name synonym)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11528928|imex:IM-24995-688	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-740322(rbpms_human)|uniprotkb:Q93062-3(isoform-parent)|ensembl:ENSG00000157110(gene)|ensembl:ENST00000339877(transcript)|entrezgene/locuslink:11030(identity)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	-	-	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:nlPMQAJoKEbPYBwsL3xodmCKd7c9606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:199B4C90B0C63374|rigid:jAPBmauEX7JrUhtS3lKietn4MpQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38340	uniprotkb:Q8WW34-2	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-11528917|ensembl:ENSP00000369959	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:q8ww34-2(display_long)|uniprotkb:TMEM239(gene name)|psi-mi:TMEM239(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11528915|imex:IM-24995-687	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	intact:EBI-9675724(isoform-parent)|uniprotkb:Q8WW34-2(isoform-parent)|ensembl:ENSG00000198326(gene)|ensembl:ENST00000380585(transcript)|entrezgene/locuslink:100288797(identity)	-	crc64:66699F37B0013088	isoform-comment:No experimental confirmation available.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:1VqWIwPpWs6WjW8eDoJUHz2pegw9606	intact-crc:8050A6F2116431FF|rigid:N6bd/BTl+wSDGwf83LA5bfD+5CM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8WVF5	uniprotkb:P38340	intact:EBI-741463|ensembl:ENSP00000368402|uniprotkb:Q5W0P9	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:kctd4_human(display_long)|uniprotkb:KCTD4(gene name)|psi-mi:KCTD4(display_short)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11528906|imex:IM-24995-686	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000180332(gene)|ensembl:ENST00000379108(transcript)|go:"GO:0051260"(protein homooligomerization)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR003131(Potassium channel, voltage dependent, Kv,  tetramerisation)|interpro:IPR011333(BTB/POZ fold)|refseq:NP_940686.2|entrezgene/locuslink:386618(identity)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	-	-	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:03cd1lqmT8fReXzYqjrKSWUdqY89606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:7D22819C1747A2EC|rigid:VEISpv+OQR1w87VcnwpVTRsUVoQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38340	uniprotkb:Q8TAP6	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-742887|ensembl:ENSP00000262127|uniprotkb:Q658N5|uniprotkb:Q9H9U7|uniprotkb:B0YJB2|uniprotkb:B4DXG5|uniprotkb:B4DZW1	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:cep76_human(display_long)|uniprotkb:CEP76(gene name)|psi-mi:CEP76(display_short)|uniprotkb:C18orf9(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11528897|imex:IM-24995-685	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	refseq:NP_079175.2|ensembl:ENSG00000101624(gene)|ensembl:ENST00000262127(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0046599"(regulation of centriole replication)|interpro:IPR028926|interpro:IPR038765|mint:Q8TAP6|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_001258918.1|entrezgene/locuslink:79959(identity)	-	crc64:66699F37B0013088	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:fWzb8oIU35oVWomyDrf8u5sbxUk9606	intact-crc:A7BAD5FC2F2F0899|rigid:b2+5OSmw5xO3lz9jgC8XS5gTSMk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8NHQ1-3	uniprotkb:P38340	intact:EBI-11526150|ensembl:ENSP00000419743	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:q8nhq1-3(display_long)|uniprotkb:CEP70(gene name)|psi-mi:CEP70(display_short)|uniprotkb:BITE(gene name synonym)|uniprotkb:p10-binding protein(gene name synonym)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11528888|imex:IM-24995-684	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114107(gene)|ensembl:ENST00000464035(transcript)|intact:EBI-739624(isoform-parent)|uniprotkb:Q8NHQ1-3(isoform-parent)|entrezgene/locuslink:80321(identity)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	-	-	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:hoF4iYo+GzWQ21hoaWZfTftWKCc9606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:C9B7ED4C34B0668A|rigid:VGCTdbYQlaQljsg+888qhNQjDFE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96EY1-3	uniprotkb:P38340	intact:EBI-11526226|ensembl:ENSP00000393970	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:q96ey1-3(display_long)|uniprotkb:DnaJ protein Tid-1(gene name synonym)|uniprotkb:HCA57(gene name synonym)|uniprotkb:Hepatocellular carcinoma-associated antigen 57(gene name synonym)|uniprotkb:TID1(gene name synonym)|uniprotkb:Tumorous imaginal discs protein Tid56 homolog(gene name synonym)|uniprotkb:DNAJA3(gene name)|psi-mi:DNAJA3(display_short)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11528982|imex:IM-24995-694	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-356767(isoform-parent)|ensembl:ENSG00000103423(gene)|ensembl:ENST00000431375(transcript)|uniprotkb:Q96EY1-3(isoform-parent)|entrezgene/locuslink:9093(identity)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	-	isoform-comment:"Ref.3 (BAG58345) sequence is in conflict in position: 33:Y->H."	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:nMH4IaOZYO5w5bh+cdX4LoPSisc9606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:6AF6839F04C479BD|rigid:k6U6xtX0na4XLi0xPmqP91pJVWY	false	sufficient binding region:60-300	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38340	uniprotkb:Q96DZ9-2	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-11522780|ensembl:ENSP00000352270|ensembl:ENSP00000497215	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:q96dz9-2(display_long)|uniprotkb:CMTM5(gene name)|psi-mi:CMTM5(display_short)|uniprotkb:CKLFSF5(gene name synonym)|uniprotkb:Chemokine-like factor superfamily member 5(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11528973|imex:IM-24995-693	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	ensembl:ENSG00000166091(gene)|ensembl:ENST00000359320(transcript)|ensembl:ENST00000649278(transcript)|intact:EBI-2548702(isoform-parent)|uniprotkb:Q96DZ9-2(isoform-parent)|entrezgene/locuslink:116173(identity)	-	crc64:66699F37B0013088	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:2TJ7rZKQNb5hH5gz9i+ujOEOIOg9606	intact-crc:723AE666B44CF252|rigid:7Tza29kWNlcvzcQUi0MEeZ+mf3s	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96CD2	uniprotkb:P38340	intact:EBI-724333|uniprotkb:Q96SX0|ensembl:ENSP00000343190|uniprotkb:Q9HC17	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:coac_human(display_long)|uniprotkb:CoaC(gene name synonym)|uniprotkb:PPCDC(gene name)|psi-mi:PPCDC(display_short)|uniprotkb:COAC(gene name synonym)|uniprotkb:MDS018(orf name)|uniprotkb:UNQ9365/PRO34154(orf name)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11528964|imex:IM-24995-692	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_068595.3|rcsb pdb:1QZU|reactome:R-HSA-196783|mint:Q96CD2|ensembl:ENSG00000138621(gene)|ensembl:ENST00000342932(transcript)|go:"GO:0004633"(phosphopantothenoylcysteine decarboxylase activity)|go:"GO:0005829"(cytosol)|go:"GO:0010181"(FMN binding)|go:"GO:0015937"(coenzyme A biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0071513"(phosphopantothenoylcysteine decarboxylase complex)|interpro:IPR003382(Flavoprotein)|interpro:IPR036551|refseq:NP_001288030.1|refseq:NP_001288031.1|refseq:NP_001288032.1|refseq:NP_001288033.1|refseq:NP_001288034.1|entrezgene/locuslink:60490(identity)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	-	-	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:2d686R1m4jA5uWpf/8O6rI6/Olo9606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:C28D71AB9EC47580|rigid:Ie5XThJd1VV+gcdIt5EeSfKwT1g	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38340	uniprotkb:Q96BR9	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-742740|uniprotkb:Q8IUL5|uniprotkb:Q8IWR9|uniprotkb:Q8N2Y5|uniprotkb:Q96BX0|ensembl:ENSP00000362609	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:zbt8a_human(display_long)|uniprotkb:ZBTB8A(gene name)|psi-mi:ZBTB8A(display_short)|uniprotkb:BOZF1(gene name synonym)|uniprotkb:BTB/POZ and zinc-finger domain-containing factor(gene name synonym)|uniprotkb:BTB/POZ and zinc-finger domains factor on chromosome 1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11528955|imex:IM-24995-691	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	ensembl:ENSG00000160062(gene)|ensembl:ENST00000373510(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|refseq:NP_001035531.2|refseq:NP_001278425.1|entrezgene/locuslink:653121(identity)	-	crc64:66699F37B0013088	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:tsrPT2tHvuBryODKgRXnceXz9s09606	intact-crc:A67EA91D87E00860|rigid:DuH/mBVmT+SjtiDNS+xDBvkP3c0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38340	uniprotkb:Q96AA8	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-752007|uniprotkb:O60302|uniprotkb:B4DSG0|uniprotkb:A4ZZA7|uniprotkb:Q548S1|uniprotkb:A8K5G5|uniprotkb:G5E9Y0|ensembl:ENSP00000265272	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:jkip2_human(display_long)|uniprotkb:JAMIP2(gene name synonym)|uniprotkb:NECC1(gene name synonym)|uniprotkb:Neuroendocrine long coiled-coil protein 1(gene name synonym)|uniprotkb:CTCL tumor antigen HD-CL-04(gene name synonym)|uniprotkb:JAKMIP2(gene name)|psi-mi:JAKMIP2(display_short)|uniprotkb:KIAA0555(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11528946|imex:IM-24995-690	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	refseq:NP_055605.2|refseq:NP_001257870.1|refseq:NP_001257863.1|refseq:NP_001269211.1|refseq:XP_016865586.1|ensembl:ENSG00000176049(gene)|ensembl:ENST00000265272(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0008017"(microtubule binding)|go:"GO:0019900"(kinase binding)|interpro:IPR024836|interpro:IPR031994|entrezgene/locuslink:9832(identity)	-	crc64:66699F37B0013088	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:WnaHkeDBQXut9F9AzzaCrDYpmAE9606	intact-crc:962DB3B8806A287D|rigid:npYgIZdHQ/NERxzGsNzFH1B4wyU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q99836	uniprotkb:P38340	intact:EBI-447677|uniprotkb:P78397|uniprotkb:Q53XS7|uniprotkb:B4DKH8|uniprotkb:B4DKU4|uniprotkb:J3KPU4|uniprotkb:J3KQ87|uniprotkb:J3KQJ6|uniprotkb:B4DQ60|uniprotkb:B4DQ72|ensembl:ENSP00000379625|ensembl:ENSP00000498360	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:myd88_human(display_long)|uniprotkb:MYD88(gene name)|psi-mi:MYD88(display_short)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11529033|imex:IM-24995-699	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001166037.1|refseq:NP_001166039.1|refseq:NP_001166040.1|refseq:NP_002459.2|dip:DIP-31349N|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032740"(positive regulation of interleukin-17 production)|go:"GO:0032747"(positive regulation of interleukin-23 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034158"(toll-like receptor 8 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042802"(identical protein binding)|go:"GO:0042832"(defense response to protozoan)|go:"GO:0050671"(positive regulation of lymphocyte proliferation)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043621"(protein self-association)|go:"GO:0045087"(innate immune response)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:1902622"(regulation of neutrophil migration)|go:"GO:2000338"("regulation of chemokine (C-X-C motif) ligand 1 production")|go:"GO:2000341"("regulation of chemokine (C-X-C motif) ligand 2 production")|interpro:IPR000157(Toll-Interleukin receptor)|interpro:IPR000488(Death)|interpro:IPR011029(DEATH-like)|interpro:IPR017281(Myeloid differentiation primary response protein MyD88)|interpro:IPR034249|interpro:IPR035897|mint:Q99836|rcsb pdb:2JS7|rcsb pdb:2Z5V|rcsb pdb:3MOP|rcsb pdb:4DOM|rcsb pdb:4EO7|rcsb pdb:6I3N|rcsb pdb:7BEQ|rcsb pdb:7BER|rcsb pdb:7L6W|reactome:R-HSA-1236974|reactome:R-HSA-1257604|reactome:R-HSA-166058|reactome:R-HSA-1810476|reactome:R-HSA-209543|reactome:R-HSA-3134963|reactome:R-HSA-5602498|reactome:R-HSA-5602680|reactome:R-HSA-5603037|reactome:R-HSA-5603041|reactome:R-HSA-6811558|reactome:R-HSA-9020702|reactome:R-HSA-975110|reactome:R-HSA-975155|reactome:R-HSA-975871|reactome:R-HSA-975138|ensembl:ENSG00000172936(gene)|ensembl:ENST00000396334(transcript)|ensembl:ENST00000650905(transcript)|go:"GO:0002238"(response to molecule of fungal origin)|go:"GO:0002269"(leukocyte activation involved in inflammatory response)|go:"GO:0002283"(neutrophil activation involved in immune response)|go:"GO:0002755"(MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0005121"(Toll binding)|go:"GO:0005123"(death receptor binding)|go:"GO:0005149"(interleukin-1 receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007254"(JNK cascade)|go:"GO:0008063"(Toll signaling pathway)|go:"GO:0009682"(induced systemic resistance)|go:"GO:0010008"(endosome membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032494"(response to peptidoglycan)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051607"(defense response to virus)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0070498"(interleukin-1-mediated signaling pathway)|go:"GO:0070555"(response to interleukin-1)|go:"GO:0070935"(3'-UTR-mediated mRNA stabilization)|go:"GO:0070944"(neutrophil-mediated killing of bacterium)|go:"GO:0070976"(TIR domain binding)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0090557"(establishment of endothelial intestinal barrier)|go:"GO:0140052"(cellular response to oxidised low-density lipoprotein particle stimulus)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:1900227"(positive regulation of NLRP3 inflammasome complex assembly)|go:"GO:0050830"(defense response to Gram-positive bacterium)|entrezgene/locuslink:4615(identity)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	-	-	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:B920s5F0eUql/jtwlByyhI7ojGI9606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:C758F87A1E155F60|rigid:9WjnDYl3V5Wej9V4AXAdqGwm5XY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38340	uniprotkb:Q96PU8	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-945792|uniprotkb:Q2I375|uniprotkb:Q5MJQ1|uniprotkb:Q969L9|uniprotkb:Q96EJ3|uniprotkb:Q96KA3|uniprotkb:Q96PU6|uniprotkb:Q96PU7|uniprotkb:Q9P0X6|uniprotkb:Q9P0X7|uniprotkb:Q9P0X8|uniprotkb:Q9P0X9|uniprotkb:Q9P0Y0|uniprotkb:Q9P0Y1|ensembl:ENSP00000355094	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:qki_human(display_long)|uniprotkb:QKI(gene name)|psi-mi:QKI(display_short)|uniprotkb:HKQ(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11529024|imex:IM-24995-698	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	refseq:NP_006766.1|refseq:NP_996735.1|refseq:NP_996736.1|refseq:NP_996737.1|refseq:NP_001288014.1|refseq:XP_011534561.1|ensembl:ENSG00000112531(gene)|ensembl:ENST00000361752(transcript)|go:"GO:0001570"(vasculogenesis)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0006417"(regulation of translation)|go:"GO:0007286"(spermatid development)|go:"GO:0008380"(RNA splicing)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0042552"(myelination)|go:"GO:0042692"(muscle cell differentiation)|go:"GO:0042759"(long-chain fatty acid biosynthetic process)|go:"GO:0045202"(synapse)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0051028"(mRNA transport)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR032367|interpro:IPR032377|interpro:IPR036612|mint:Q96PU8|rcsb pdb:4JVH|reactome:R-HSA-6802952|entrezgene/locuslink:9444(identity)	-	crc64:66699F37B0013088	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:7dcw5OyNAhQTE+yTch3qbSlZJdE9606	intact-crc:FE3BAB1F8F549E1A|rigid:gys1RPpQVAeyV88aDboHQby7lpw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96MF2	uniprotkb:P38340	intact:EBI-745680|uniprotkb:B4DUK9|uniprotkb:Q96HU5|ensembl:ENSP00000329200	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:stac3_human(display_long)|uniprotkb:STAC3(gene name)|psi-mi:STAC3(display_short)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11529013|imex:IM-24995-697	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001273185.1|refseq:NP_001273186.1|refseq:NP_659501.1|refseq:XP_011536428.1|ensembl:ENSG00000185482(gene)|ensembl:ENST00000332782(transcript)|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0030315"(T-tubule)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:1901387"(positive regulation of voltage-gated calcium channel activity)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|interpro:IPR001452(Src homology-3)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR035736|interpro:IPR036028|interpro:IPR039688|mint:Q96MF2|rcsb pdb:2DB6|rcsb pdb:6B29|rcsb pdb:6UY7|rcsb pdb:6UY8|rcsb pdb:6UY9|entrezgene/locuslink:246329(identity)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	-	-	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:PzyVrp74OzLhtbODzinH5fHSGRc9606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:5D7B925DB654CB40|rigid:7E6s5XTKhed7xn4oHkLVynXBEvY	false	sufficient binding region:40-364	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38340	uniprotkb:Q96MA1	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-954466|uniprotkb:Q96SD2|ensembl:ENSP00000360500	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:dmrtb_human(display_long)|uniprotkb:DMRTB1(gene name)|psi-mi:DMRTB1(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11529002|imex:IM-24995-696	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|ensembl:ENSG00000143006(gene)|ensembl:ENST00000371445(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007281"(germ cell development)|go:"GO:0007548"(sex differentiation)|go:"GO:0046872"(metal ion binding)|interpro:IPR001275(DM DNA-binding)|interpro:IPR026607|interpro:IPR036407|mint:Q96MA1|refseq:NP_149056.1|ensembl:ENSP00000360500|entrezgene/locuslink:63948(identity)	-	crc64:66699F37B0013088	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:GU1xgsv/Oyy91PEorOlxBqAvIzc9606	intact-crc:EC0CE3CC39F792EA|rigid:XEOf/4DkhSl+14Sc5v3TJ+135Jo	false	-	sufficient binding region:154-342	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96HR9	uniprotkb:P38340	intact:EBI-750345|uniprotkb:Q96LM0|uniprotkb:B2RE01|uniprotkb:A0A1L5BXV3|uniprotkb:D6W5Z0|ensembl:ENSP00000378861	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:reep6_human(display_long)|uniprotkb:Polyposis locus protein 1-like 1(gene name synonym)|uniprotkb:REEP6(gene name)|psi-mi:REEP6(display_short)|uniprotkb:C19orf32(gene name synonym)|uniprotkb:DP1L1(gene name synonym)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11528993|imex:IM-24995-695	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_612402.1|refseq:NP_001316485.1|ensembl:ENSG00000115255(gene)|ensembl:ENST00000395479(transcript)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030665"(clathrin-coated vesicle membrane)|go:"GO:0032386"(regulation of intracellular transport)|go:"GO:0050908"(detection of light stimulus involved in visual perception)|interpro:IPR004345(TB2/DP1 and HVA22 related protein)|mint:Q96HR9|reactome:R-HSA-381753|go:"GO:0005634"(nucleus)|entrezgene/locuslink:92840(identity)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	-	-	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2017/05/05	rogid:pB8AjjNTpmaaLJ8j7MCBM45UAHE9606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:15F787B8740643B5|rigid:L17CSpZs0kLHM9zevg3Ez0Ws3s4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9BYV6-2	uniprotkb:P38340	intact:EBI-11522718|ensembl:ENSP00000297348	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:q9byv6-2(display_long)|uniprotkb:TRIM55(gene name)|psi-mi:TRIM55(display_short)|uniprotkb:MURF2(gene name synonym)|uniprotkb:Muscle-specific RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 29(gene name synonym)|uniprotkb:RNF29(gene name synonym)|uniprotkb:p50(isoform synonym)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11529078|imex:IM-24995-704	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-2341179(isoform-parent)|uniprotkb:Q9BYV6-2(isoform-parent)|ensembl:ENSG00000147573(gene)|ensembl:ENST00000353317(transcript)|entrezgene/locuslink:84675(identity)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	-	-	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:9t8UhK+Z1yBqjnQrOqPD76NuXGg9606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:EAEC37E05B921510|rigid:D6TuJ5LQQI7/fHckMWSouMivIz0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9BV19	uniprotkb:P38340	intact:EBI-2874661|ensembl:ENSP00000361603	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:ca050_human(display_long)|uniprotkb:C1orf50(gene name)|psi-mi:C1orf50(display_short)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11529069|imex:IM-24995-703	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000164008(gene)|ensembl:ENST00000372525(transcript)|go:"GO:0042802"(identical protein binding)|interpro:IPR019534|refseq:NP_077002.2|entrezgene/locuslink:79078(identity)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	-	-	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:TZfvza3lr44CQW5Piu+83qv5Igo9606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:A90D7C9E84A7AB9F|rigid:apcvklzGvvboxdB4d6bfWHA+zIQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9BUZ4	uniprotkb:P38340	intact:EBI-3650647|uniprotkb:O75615|uniprotkb:Q14848|uniprotkb:Q2KJU4|uniprotkb:Q2PJN8|ensembl:ENSP00000262395	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:traf4_human(display_long)|uniprotkb:TRAF4(gene name)|psi-mi:TRAF4(display_short)|uniprotkb:CART1(gene name synonym)|uniprotkb:MLN62(gene name synonym)|uniprotkb:RNF83(gene name synonym)|uniprotkb:Cysteine-rich domain associated with RING and Traf domains protein 1(gene name synonym)|uniprotkb:Metastatic lymph node gene 62 protein(gene name synonym)|uniprotkb:RING finger protein 83(gene name synonym)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11529060|imex:IM-24995-702	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004286.2|dip:DIP-40910N|ensembl:ENSG00000076604(gene)|ensembl:ENST00000262395(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006915"(apoptotic process)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030323"(respiratory tube development)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031996"(thioesterase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050699"(WW domain binding)|interpro:IPR001293(Zinc finger, TRAF-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|interpro:IPR012227(TNF receptor-associated factor TRAF)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018957|interpro:IPR027138|interpro:IPR037307|interpro:IPR043211|mint:Q9BUZ4|rcsb pdb:2EOD|rcsb pdb:2YUC|rcsb pdb:3ZJB|rcsb pdb:4K8U|rcsb pdb:4M4E|rcsb pdb:5YC1|entrezgene/locuslink:9618(identity)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	-	-	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:9Bjl/NCcleyKgZb7suHw3AVWpG09606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:3762B75E00AA7AC9|rigid:IG24QeboR2KuQKIq2Km2w4i+Gto	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9BPX1	uniprotkb:P38340	intact:EBI-742664|uniprotkb:Q9UKU3|ensembl:ENSP00000263278	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:dhb14_human(display_long)|uniprotkb:DHRS10(gene name synonym)|uniprotkb:Dehydrogenase/reductase SDR family member 10(gene name synonym)|uniprotkb:17-beta-hydroxysteroid dehydrogenase DHRS10(gene name synonym)|uniprotkb:Retinal short-chain dehydrogenase/reductase retSDR3(gene name synonym)|uniprotkb:HSD17B14(gene name)|psi-mi:HSD17B14(display_short)|uniprotkb:SDR3(gene name synonym)|uniprotkb:SDR47C1(gene name synonym)|uniprotkb:Short chain dehydrogenase/reductase family 47C member 1(gene name synonym)|uniprotkb:UNQ502/PRO474(orf name)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11529051|imex:IM-24995-701	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_057330.2|ensembl:ENSG00000087076(gene)|ensembl:ENST00000263278(transcript)|go:"GO:0004303"(estradiol 17-beta-dehydrogenase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006706"(steroid catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0044594"("17-beta-hydroxysteroid dehydrogenase (NAD+) activity")|go:"GO:0047045"("testosterone 17-beta-dehydrogenase (NADP+) activity")|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR020904|interpro:IPR036291|rcsb pdb:1YDE|rcsb pdb:5EN4|rcsb pdb:5HS6|rcsb pdb:5ICM|rcsb pdb:5ICS|rcsb pdb:5JS6|rcsb pdb:5JSF|rcsb pdb:5L7T|rcsb pdb:5L7W|rcsb pdb:5L7Y|rcsb pdb:5O42|rcsb pdb:5O43|rcsb pdb:5O6O|rcsb pdb:5O6X|rcsb pdb:5O6Z|rcsb pdb:5O72|rcsb pdb:5O7C|rcsb pdb:6EMM|rcsb pdb:6FFB|rcsb pdb:6G4L|rcsb pdb:6GBT|rcsb pdb:6GTB|rcsb pdb:6GTU|rcsb pdb:6H0M|rcsb pdb:6HNO|rcsb pdb:6QCK|rcsb pdb:6ZDE|rcsb pdb:6ZDI|reactome:R-HSA-193144|entrezgene/locuslink:51171(identity)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	-	-	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:/t03kHO/EWlqKNv7+TkWbTV9jpM9606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:F7CB8A6F09E33560|rigid:YpBKWwGDzxQyIyVR8BXnGsfOtRo	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q99942	uniprotkb:P38340	intact:EBI-348482|ensembl:ENSP00000364235|ensembl:ENSP00000387879|ensembl:ENSP00000388795|ensembl:ENSP00000401172|ensembl:ENSP00000413131|ensembl:ENSP00000415127|ensembl:ENSP00000415784|uniprotkb:A2BFI6|uniprotkb:Q0VDB7|uniprotkb:Q9UMQ2|uniprotkb:B2R4K3	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:rnf5_human(display_long)|uniprotkb:RNF5(gene name)|psi-mi:RNF5(display_short)|uniprotkb:G16(gene name synonym)|uniprotkb:RING finger protein 5(gene name synonym)|uniprotkb:Protein G16(gene name synonym)|uniprotkb:NG2(gene name synonym)|uniprotkb:RMA1(gene name synonym)|uniprotkb:Ram1 homolog(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF5(gene name synonym)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11529042|imex:IM-24995-700	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_008844.1|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009617"(response to bacterium)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031648"(protein destabilization)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0036503"(ERAD pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0044257"(cellular protein catabolic process)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0044390"(ubiquitin-like protein conjugating enzyme binding)|ensembl:ENST00000456167(transcript)|ensembl:ENSG00000183574(gene)|ensembl:ENSG00000204308(gene)|ensembl:ENSG00000223767(gene)|ensembl:ENSG00000225452(gene)|ensembl:ENSG00000227277(gene)|ensembl:ENSG00000228405(gene)|ensembl:ENSG00000228907(gene)|ensembl:ENST00000375094(transcript)|ensembl:ENST00000413786(transcript)|ensembl:ENST00000432616(transcript)|ensembl:ENST00000445885(transcript)|ensembl:ENST00000449794(transcript)|ensembl:ENST00000453473(transcript)|go:"GO:0055085"(transmembrane transport)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|go:"GO:2000785"(regulation of autophagosome assembly)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|reactome:R-HSA-382556|reactome:R-HSA-5678895|reactome:R-HSA-901032|go:"GO:0044877"(protein-containing complex binding)|dip:DIP-29268N|entrezgene/locuslink:6048(identity)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	-	-	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:eHlCD+xbWmpzFdhVn6OC5MPqeNE9606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:3DD10E7FC4392FD5|rigid:wnWWHJark3LiQ8F96socQHho5FA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38340	uniprotkb:Q9NRY6	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-750734|uniprotkb:Q567U0|uniprotkb:Q8NBW6|uniprotkb:Q96F13|uniprotkb:A8K252|ensembl:ENSP00000316021|ensembl:ENSP00000459019|ensembl:ENSP00000459419|ensembl:ENSP00000491350|ensembl:ENSP00000491393|ensembl:ENSP00000492026|ensembl:ENSP00000492083|ensembl:ENSP00000483743	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:pls3_human(display_long)|uniprotkb:"Ca(2+)-dependent phospholipid scramblase 3"(gene name synonym)|uniprotkb:PLSCR3(gene name)|psi-mi:PLSCR3(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11529123|imex:IM-24995-709	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	refseq:NP_001188505.1|refseq:NP_065093.2|ensembl:ENSG00000187838(gene)|ensembl:ENSG00000284009(gene)|ensembl:ENST00000324822(transcript)|ensembl:ENST00000574401(transcript)|ensembl:ENST00000576201(transcript)|ensembl:ENST00000619711(transcript)|ensembl:ENST00000639780(transcript)|ensembl:ENST00000639874(transcript)|ensembl:ENST00000640053(transcript)|ensembl:ENST00000640375(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017121"(plasma membrane phospholipid scrambling)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0017128"(phospholipid scramblase activity)|go:"GO:0032049"(cardiolipin biosynthetic process)|go:"GO:0032791"(lead ion binding)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043621"(protein self-association)|go:"GO:0045340"(mercury ion binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0090199"(regulation of release of cytochrome c from mitochondria)|interpro:IPR005552(Scramblase)|entrezgene/locuslink:57048(identity)	-	crc64:66699F37B0013088	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:JKzacFCwrCQpcI3EJsLvpAbLFCA9606	intact-crc:144188B266CCC8FE|rigid:kYHWB6acjNUbKK6TPDe1djT2Fc0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9NQC3-3	uniprotkb:P38340	intact:EBI-11526335|ensembl:ENSP00000378107	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:q9nqc3-3(display_long)|uniprotkb:Foocen(gene name synonym)|uniprotkb:KIAA0886(gene name synonym)|uniprotkb:NOGO(gene name synonym)|uniprotkb:Neurite outgrowth inhibitor(gene name synonym)|uniprotkb:Neuroendocrine-specific protein(gene name synonym)|uniprotkb:Neuroendocrine-specific protein C homolog(gene name synonym)|uniprotkb:RTN-x(gene name synonym)|uniprotkb:Reticulon-5(gene name synonym)|uniprotkb:My043(orf name)|uniprotkb:SP1507(orf name)|uniprotkb:Foocen-S(isoform synonym)|uniprotkb:Nogo-C(isoform synonym)|uniprotkb:RTN4(gene name)|psi-mi:RTN4(display_short)|uniprotkb:RTN4C(isoform synonym)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11529114|imex:IM-24995-708	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-715945(isoform-parent)|ensembl:ENSG00000115310(gene)|ensembl:ENST00000394609(transcript)|entrezgene/locuslink:57142(identity)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	-	-	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Iq/LlFtXjFyIIfxZ1l3NTKURpyA9606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:6B88EF6DB07FA4BB|rigid:RPbYVC0UaomGCxRAx3vYWwqIvCQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38340	uniprotkb:Q9HCK0	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-3918996|ensembl:ENSP00000362758|ensembl:ENSP00000362760|uniprotkb:B3KQ53|uniprotkb:Q8WTR1	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:zbt26_human(display_long)|uniprotkb:ZBTB26(gene name)|psi-mi:ZBTB26(display_short)|uniprotkb:KIAA1572(gene name synonym)|uniprotkb:ZNF481(gene name synonym)|uniprotkb:Zinc finger protein 481(gene name synonym)|uniprotkb:Zinc finger protein Bioref(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11529105|imex:IM-24995-707	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	ensembl:ENSG00000171448(gene)|ensembl:ENST00000373654(transcript)|ensembl:ENST00000373656(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|refseq:NP_001291292.1|refseq:NP_001291293.1|refseq:NP_065975.1|entrezgene/locuslink:57684(identity)	-	crc64:66699F37B0013088	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:o5XKyl1Z7AtQOJH5HBqkYh5w1n89606	intact-crc:30ED42A9A2372D88|rigid:Ft7v8Okidfj2nRLaVFStbCWJREY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9HAN9	uniprotkb:P38340	intact:EBI-3917542|uniprotkb:Q8TAE9|uniprotkb:Q9H6B6|uniprotkb:Q9H247|uniprotkb:B1AN63|ensembl:ENSP00000366410|ensembl:ENSP00000435134	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:nmna1_human(display_long)|uniprotkb:NMNAT1(gene name)|psi-mi:NMNAT1(display_short)|uniprotkb:NMNAT(gene name synonym)|uniprotkb:Nicotinate-nucleotide adenylyltransferase 1(gene name synonym)|uniprotkb:Nicotinamide-nucleotide adenylyltransferase 1(gene name synonym)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11529096|imex:IM-24995-706	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001284707.1|refseq:NP_073624.2|ensembl:ENSG00000173614(gene)|ensembl:ENST00000377205(transcript)|ensembl:ENST00000462686(transcript)|go:"GO:0000309"(nicotinamide-nucleotide adenylyltransferase activity)|go:"GO:0004515"(nicotinate-nucleotide adenylyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0009165"(nucleotide biosynthetic process)|go:"GO:0009435"(NAD biosynthetic process)|go:"GO:0009611"(response to wounding)|go:"GO:0016604"(nuclear body)|go:"GO:0042802"(identical protein binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:1902511"(negative regulation of apoptotic DNA fragmentation)|go:"GO:1990966"(ATP generation from poly-ADP-D-ribose)|interpro:IPR004821(Cytidyltransferase-related)|interpro:IPR005248(Probable nicotinate-nucleotide adenylyltransferase)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|mint:Q9HAN9|rcsb pdb:1GZU|rcsb pdb:1KKU|rcsb pdb:1KQN|rcsb pdb:1KQO|rcsb pdb:1KR2|reactome:R-HSA-196807|refseq:XP_016857596.1|dip:DIP-60881N|entrezgene/locuslink:64802(identity)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	-	-	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:KwV9lz04z3ptlVpKu3b534Yekpc9606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:A3D4EDE8BACEA35C|rigid:TsLbVS534F30ED4+TUYXBnjmJXc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9C0F1	uniprotkb:P38340	intact:EBI-744115|uniprotkb:A8K8W9|uniprotkb:B3KT53|uniprotkb:Q8IXZ4|uniprotkb:A8MW11|uniprotkb:D3DP42|ensembl:ENSP00000296519|ensembl:ENSP00000380009|ensembl:ENSP00000423153	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:cep44_human(display_long)|uniprotkb:HBV PreS1-transactivated protein 3(gene name synonym)|uniprotkb:CEP44(gene name)|psi-mi:CEP44(display_short)|uniprotkb:KIAA1712(gene name synonym)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11529087|imex:IM-24995-705	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001035247.1|refseq:NP_001138786.1|refseq:XP_011530587.1|refseq:XP_011530588.1|refseq:XP_011530589.1|refseq:XP_016864143.1|refseq:XP_016864144.1|ensembl:ENSG00000164118(gene)|ensembl:ENST00000296519(transcript)|ensembl:ENST00000396791(transcript)|ensembl:ENST00000503780(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007099"(centriole replication)|go:"GO:0008017"(microtubule binding)|go:"GO:0010457"(centriole-centriole cohesion)|go:"GO:0030496"(midbody)|interpro:IPR029157|interpro:IPR033603|mint:Q9C0F1|entrezgene/locuslink:80817(identity)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	-	-	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:gDTC64oDhudGdsssC7v+suIHZkA9606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:56B9B4DFC59E8141|rigid:b9Pj/2akUY0/l21/+ZcQGgH58UM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38340	uniprotkb:Q9UHX1-2	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-11529177|ensembl:ENSP00000322036|ensembl:ENSP00000478495	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:q9uhx1-2(display_long)|uniprotkb:PUF60(gene name)|psi-mi:PUF60(display_short)|uniprotkb:"60 kDa poly(U)-binding-splicing factor"(gene name synonym)|uniprotkb:FIR(gene name synonym)|uniprotkb:FUSE-binding protein-interacting repressor(gene name synonym)|uniprotkb:ROBPI(gene name synonym)|uniprotkb:Ro-binding protein 1(gene name synonym)|uniprotkb:SIAHBP1(gene name synonym)|uniprotkb:Siah-binding protein 1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11529181|imex:IM-24995-715	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	intact:EBI-1053259(isoform-parent)|ensembl:ENSG00000179950(gene)|ensembl:ENSG00000274081(gene)|ensembl:ENST00000349157(transcript)|ensembl:ENST00000612237(transcript)|uniprotkb:Q9UHX1-2(isoform-parent)|entrezgene/locuslink:22827(identity)	-	crc64:66699F37B0013088	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:snVN9Lw5+MP2/aiq4z08ANwvr209606	intact-crc:9593DF5773B512D4|rigid:9yjNEVIDBi5WlCsKOQdzJS9UL3I	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UDV6	uniprotkb:P38340	intact:EBI-1640204|uniprotkb:Q13396|uniprotkb:Q8N664|uniprotkb:B2RCF4|ensembl:ENSP00000338572	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:zn212_human(display_long)|uniprotkb:ZNF212(gene name)|psi-mi:ZNF212(display_short)|uniprotkb:ZNFC150(gene name synonym)|uniprotkb:Zinc finger protein C2H2-150(gene name synonym)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11529168|imex:IM-24995-714	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_036388.2|ensembl:ENSG00000170260(gene)|ensembl:ENST00000335870(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR022137|interpro:IPR036051|interpro:IPR036236|mint:Q9UDV6|reactome:R-HSA-212436|entrezgene/locuslink:7988(identity)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	-	-	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:jZtScr5t/MR83+d1tdA9OiP4JCA9606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:EFF18D790D74906D|rigid:qXq1mnyZehMkMSTEz8juyKSjq8E	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38340	uniprotkb:Q9P2A4	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-742038|uniprotkb:C9IZN8|ensembl:ENSP00000225941|uniprotkb:Q9H0P6	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:abi3_human(display_long)|uniprotkb:New molecule including SH3(gene name synonym)|uniprotkb:ABI3(gene name)|psi-mi:ABI3(display_short)|uniprotkb:NESH(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11529159|imex:IM-24995-713	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	refseq:NP_001128658.1|refseq:NP_057512.1|ensembl:ENSG00000108798(gene)|ensembl:ENST00000225941(transcript)|go:"GO:0002357"(defense response to tumor cell)|go:"GO:0005737"(cytoplasm)|go:"GO:0010593"(negative regulation of lamellipodium assembly)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031209"(SCAR complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0051015"(actin filament binding)|go:"GO:0061001"(regulation of dendritic spine morphogenesis)|go:"GO:0099151"(regulation of postsynaptic density assembly)|go:"GO:1900028"(negative regulation of ruffle assembly)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|go:"GO:2000249"(regulation of actin cytoskeleton reorganization)|go:"GO:2000774"(positive regulation of cellular senescence)|interpro:IPR001452(Src homology-3)|interpro:IPR012849(Abl-interactor, homeo-domain homologous region)|interpro:IPR028455|interpro:IPR028457|interpro:IPR036028|mint:Q9P2A4|entrezgene/locuslink:51225(identity)	-	crc64:66699F37B0013088	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:VAjz40ulLa5L+GmfL7ia5wTDND49606	intact-crc:3B2F1C4D5FFDE2D3|rigid:ZzmrJLOHIzqscfc6FvWmLPw50F8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9NWS6	uniprotkb:P38340	intact:EBI-8638992|uniprotkb:B4DY02|ensembl:ENSP00000216214|ensembl:ENSP00000395892|intact:MINT-8162875|uniprotkb:Q5TII5|uniprotkb:B3KWG4|uniprotkb:Q96CY3	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:f118a_human(display_long)|uniprotkb:FAM118A(gene name)|psi-mi:FAM118A(display_short)|uniprotkb:C22orf8(gene name synonym)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11529150|imex:IM-24995-712	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000100376(gene)|ensembl:ENST00000216214(transcript)|ensembl:ENST00000441876(transcript)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|interpro:IPR033353|interpro:IPR038916|interpro:IPR039444|refseq:NP_060381.2|refseq:NP_001098065.1|entrezgene/locuslink:55007(identity)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	-	comment:mint	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:zZMOyeZwAeoDNLBQ9EKYRw4+0BM9606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:E2E2ECC2318FC1CE|rigid:ViXk1gZdB3sdHGkhG4tOPMJF124	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38340	uniprotkb:Q9NVV9	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-741515|uniprotkb:Q53FQ1|uniprotkb:Q6IA99|ensembl:ENSP00000254250|uniprotkb:A6NCB6|uniprotkb:D3DSY5|uniprotkb:H9KV49	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:thap1_human(display_long)|uniprotkb:THAP1(gene name)|psi-mi:THAP1(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11529141|imex:IM-24995-711	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	refseq:NP_060575.1|ensembl:ENSG00000131931(gene)|ensembl:ENST00000254250(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001650"(fibrillar center)|go:"GO:0001935"(endothelial cell proliferation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007049"(cell cycle)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016605"(PML body)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR006612(Zinc finger, C2CH-type)|interpro:IPR026516|interpro:IPR038441|mint:Q9NVV9|rcsb pdb:2JTG|rcsb pdb:2KO0|rcsb pdb:2L1G|refseq:NP_945354.1|entrezgene/locuslink:55145(identity)	-	crc64:66699F37B0013088	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:/KO90pu5tBnIVq9SMx1JYPXFCEQ9606	intact-crc:0926D1B0CA178E05|rigid:nXSsDqXxvAuQuiN3QMDBNnUTHxk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9NSC5	uniprotkb:P38340	intact:EBI-748420|uniprotkb:O14580|uniprotkb:O95350|uniprotkb:Q9NSB9|uniprotkb:Q9NSC0|intact:EBI-2557809|uniprotkb:E9PCW9|uniprotkb:Q9NSC1|intact:EBI-28972925|ensembl:ENSP00000376162|ensembl:ENSP00000439937|ensembl:ENSP00000446026|intact:EBI-10175777|uniprotkb:B2RA10	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:home3_human(display_long)|uniprotkb:HOMER3(gene name)|psi-mi:HOMER3(display_short)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11529132|imex:IM-24995-710	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000221222|ensembl:ENSP00000221222|ensembl:ENSP00000376162|ensembl:ENST00000433218|ensembl:ENSP00000396154|ensembl:ENSP00000439937|ensembl:ENSP00000446026|ensembl:ENST00000594439|ensembl:ENSP00000471835|refseq:XP_006723006.1|refseq:XP_006723007.1|refseq:NP_001139193.1|refseq:NP_001139194.1|refseq:NP_004829.3|refseq:NP_001139196.1|ensembl:ENSG00000051128(gene)|ensembl:ENST00000392351(transcript)|ensembl:ENST00000539827(transcript)|ensembl:ENST00000542541(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006605"(protein targeting)|go:"GO:0007216"(G protein-coupled glutamate receptor signaling pathway)|go:"GO:0014069"(postsynaptic density)|go:"GO:0030425"(dendrite)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0035256"(G protein-coupled glutamate receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|go:"GO:2001256"(regulation of store-operated calcium entry)|interpro:IPR000697(EVH1)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR044100|mint:Q9NSC5|rcsb pdb:2P8V|rcsb pdb:3CVF|reactome:R-HSA-6794361|entrezgene/locuslink:9454(identity)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	-	-	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:U1y/y52nnf7zQUCNQlqk7JDgXi49606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:86BA15D596E30E9A|rigid:MadKq7FrrRQ7KphkPSb9mHcWQFQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9Y281	uniprotkb:P38340	intact:EBI-351218|uniprotkb:G3V5P4|ensembl:ENSP00000298159|ensembl:ENSP00000340635|ensembl:ENSP00000500375|ensembl:ENSP00000500532	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:cof2_human(display_long)|uniprotkb:CFL2(gene name)|psi-mi:CFL2(display_short)|uniprotkb:Cofilin, muscle isoform(gene name synonym)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11529230|imex:IM-24995-720	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_068733.1|refseq:NP_619579.1|refseq:XP_011534665.1|refseq:NP_001230574.1|dip:DIP-33178N|ensembl:ENSG00000165410(gene)|ensembl:ENST00000298159(transcript)|ensembl:ENST00000341223(transcript)|ensembl:ENST00000672163(transcript)|ensembl:ENST00000672517(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016363"(nuclear matrix)|go:"GO:0030018"(Z disc)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030043"(actin filament fragmentation)|go:"GO:0030836"(positive regulation of actin filament depolymerization)|go:"GO:0031674"(I band)|go:"GO:0045214"(sarcomere organization)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0048870"(cell motility)|go:"GO:0051014"(actin filament severing)|go:"GO:0051015"(actin filament binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002108(Actin-binding, cofilin/tropomyosin type)|interpro:IPR017904|interpro:IPR029006|mint:Q9Y281|entrezgene/locuslink:1073(identity)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	-	-	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:HwYoUPZRkuRzqMLvuQctwNCOREA9606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:60D34D2B58412C78|rigid:dkDxg6oyNPMCnLXoGQkGZlDBp1E	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9ULA0	uniprotkb:P38340	intact:EBI-748356|uniprotkb:Q9BW44|uniprotkb:Q9NUV5|uniprotkb:Q9NV55|ensembl:ENSP00000273075	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:dnpep_human(display_long)|uniprotkb:ASPEP(gene name synonym)|uniprotkb:DAP(gene name synonym)|uniprotkb:DNPEP(gene name)|psi-mi:DNPEP(display_short)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11529221|imex:IM-24995-719	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306049.1|refseq:NP_036232.2|ensembl:ENSG00000123992(gene)|ensembl:ENST00000273075(transcript)|go:"GO:0004177"(aminopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006518"(peptide metabolic process)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0072562"(blood microparticle)|interpro:IPR001948(Peptidase M18, aminopeptidase I)|interpro:IPR023358|rcsb pdb:4DYO|entrezgene/locuslink:23549(identity)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	-	-	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2020/10/21	rogid:xG06vZosglPmA5ktZd8A8EH9h0g9606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:A16D17C3F15C3E19|rigid:Fp77wJo8+HbRZpyPHuZBtGTjUXA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UI14	uniprotkb:P38340	intact:EBI-712367|ensembl:ENSP00000222008|uniprotkb:Q7Z4Y2|uniprotkb:Q9Y3R1	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:praf1_human(display_long)|uniprotkb:PRA1 family protein 1(gene name synonym)|uniprotkb:RABAC1(gene name)|psi-mi:RABAC1(display_short)|uniprotkb:PRA1(gene name synonym)|uniprotkb:PRAF1(gene name synonym)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11529212|imex:IM-24995-718	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006414.2|ensembl:ENSG00000105404(gene)|ensembl:ENST00000222008(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0070064"(proline-rich region binding)|interpro:IPR004895(Prenylated rab acceptor PRA1)|mint:Q9UI14|entrezgene/locuslink:10567(identity)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	-	-	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:WS2rUY7yXRbR7pqWgfUCbnEiDbg9606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:25CEF454997223D3|rigid:BK1n3/d6sldlD+wVYtMoikRhz2E	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38340	uniprotkb:Q9UHX1-6	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-11085298|ensembl:ENSP00000431960	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:q9uhx1-6(display_long)|uniprotkb:PUF60(gene name)|psi-mi:PUF60(display_short)|uniprotkb:"60 kDa poly(U)-binding-splicing factor"(gene name synonym)|uniprotkb:FIR(gene name synonym)|uniprotkb:FUSE-binding protein-interacting repressor(gene name synonym)|uniprotkb:ROBPI(gene name synonym)|uniprotkb:Ro-binding protein 1(gene name synonym)|uniprotkb:SIAHBP1(gene name synonym)|uniprotkb:Siah-binding protein 1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11529201|imex:IM-24995-717	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	ensembl:ENSG00000179950(gene)|ensembl:ENST00000527197(transcript)|intact:EBI-1053259(isoform-parent)|uniprotkb:Q9UHX1-6(isoform-parent)|entrezgene/locuslink:22827(identity)	-	crc64:66699F37B0013088	isoform-comment:"Contains a glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) at position 14."	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:rSsTImwmpEAWMCxLzF5Y4zVdeFM9606	intact-crc:1121634E71654EFA|rigid:AGw+HnxGbnqrYFDQxeuC0bO441g	false	-	sufficient binding region:15-513	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UHX1-5	uniprotkb:P38340	intact:EBI-11526420|ensembl:ENSP00000395417|ensembl:ENSP00000478209	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:q9uhx1-5(display_long)|uniprotkb:PUF60(gene name)|psi-mi:PUF60(display_short)|uniprotkb:"60 kDa poly(U)-binding-splicing factor"(gene name synonym)|uniprotkb:FIR(gene name synonym)|uniprotkb:FUSE-binding protein-interacting repressor(gene name synonym)|uniprotkb:ROBPI(gene name synonym)|uniprotkb:Ro-binding protein 1(gene name synonym)|uniprotkb:SIAHBP1(gene name synonym)|uniprotkb:Siah-binding protein 1(gene name synonym)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11529190|imex:IM-24995-716	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-1053259(isoform-parent)|ensembl:ENSG00000179950(gene)|ensembl:ENSG00000274081(gene)|ensembl:ENST00000456095(transcript)|ensembl:ENST00000620953(transcript)|entrezgene/locuslink:22827(identity)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	-	isoform-comment:"Contains a glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) at position 14."	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:PSbIU++DIL6ysF0ccd3ZHzeJ5rs9606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:DF2834A7DEBC57FB|rigid:arMDTNRejdWEm+w41YUmN6muyD8	false	sufficient binding region:15-530	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8NF64	uniprotkb:P38635	intact:EBI-745786|uniprotkb:O94790|uniprotkb:Q0VGB4|uniprotkb:Q659A8|uniprotkb:Q6JKL5|uniprotkb:Q8WTX8|uniprotkb:Q96Q01|uniprotkb:Q9BQH7|uniprotkb:A4D2K7|uniprotkb:D3DVL1|intact:EBI-28976701|ensembl:ENSP00000311778|ensembl:ENSP00000414723	intact:EBI-2045554|uniprotkb:D6VTQ5|ensemblfungi:YFR025C	psi-mi:zmiz2_human(display_long)|uniprotkb:PIAS-like protein Zimp7(gene name synonym)|uniprotkb:ZMIZ2(gene name)|psi-mi:ZMIZ2(display_short)|uniprotkb:KIAA1886(gene name synonym)|uniprotkb:HRIHFB2007(orf name)|uniprotkb:ZIMP7(gene name synonym)	psi-mi:his9_yeast(display_long)|uniprotkb:YFR025C(locus name)|uniprotkb:HIS2(gene name)|psi-mi:HIS2(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11529266|imex:IM-24995-724	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_113637.3|refseq:NP_777589.2|ensembl:ENST00000265346|ensembl:ENSP00000265346|ensembl:ENSP00000311778|ensembl:ENST00000413916|ensembl:ENSP00000409648|ensembl:ENSP00000414723|refseq:NP_001287888.1|ensembl:ENSG00000122515(gene)|ensembl:ENST00000309315(transcript)|ensembl:ENST00000441627(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048096"|interpro:IPR004181(Zinc finger, MIZ-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|refseq:XP_005249926.1|refseq:XP_005249929.1|entrezgene/locuslink:83637(identity)	refseq:NP_116681.1|sgd:S000001921|interpro:IPR010140(Histidinol phosphate phosphatase, HisJ)|interpro:IPR004013(PHP, C-terminal)|interpro:IPR016195(Polymerase and histidinol phosphatase-like)|mint:P38635|ensemblfungi:YFR025C(gene)|ensemblfungi:YFR025C_mRNA(transcript)|go:"GO:0000105"(histidine biosynthetic process)|go:"GO:0004401"(histidinol-phosphatase activity)|go:"GO:0005737"(cytoplasm)|sgd:YFR025C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:gkO57EyOLACt/8WYxFQbasiqRro9606	rogid:3gGqFDbJWtM4it1O4HJjk6KoTL4559292	intact-crc:A1DB8FE9BDA5768B|rigid:BOZGMKK7jJJWJv9E7l0s2M5uWlo	false	sufficient binding region:479-920	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96BA8	uniprotkb:P38374	intact:EBI-6942903|ensembl:ENSP00000481956|intact:MINT-268046|intact:MINT-8162577|uniprotkb:Q8N2D5|uniprotkb:Q96CP0	intact:EBI-29585|uniprotkb:D6VQF8|ensemblfungi:YBR162W-A	psi-mi:cr3l1_human(display_long)|uniprotkb:CREB3L1(gene name)|psi-mi:CREB3L1(display_short)|uniprotkb:OASIS(gene name synonym)|uniprotkb:PSEC0238(orf name)|uniprotkb:Old astrocyte specifically-induced substance(gene name synonym)	psi-mi:ysy6_yeast(display_long)|uniprotkb:YSY6(gene name)|psi-mi:YSY6(display_short)|uniprotkb:YBR162BW(orf name)|uniprotkb:YBR162W-A(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11529257|imex:IM-24995-723	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157613(gene)|ensembl:ENST00000621158(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0070278"(extracellular matrix constituent secretion)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029805|mint:Q96BA8|reactome:R-HSA-8874211|refseq:NP_443086.1|entrezgene/locuslink:90993(identity)	sgd:S000002158|refseq:NP_009721.1|dip:DIP-4936N|reactome:R-SCE-9609523|ensemblfungi:YBR162W-A(gene)|ensemblfungi:YBR162W-A_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006486"(protein glycosylation)|go:"GO:0009306"(protein secretion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|interpro:IPR010580(Ribosome associated membrane RAMP4)|sgd:YBR162W-A(identity)	-	comment:mint|function:"Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE"	crc64:326410AB4772B33D	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:sMWUFmBeBBCO+T0Y2CuB/un1lBg9606	rogid:FwDeAMLCEaMmEgCDK1xjQS4MDFg559292	intact-crc:3ABAA059E73B4921|rigid:wrj9U3bRG1qZzkdHsBORIH0Q+2s	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38340	uniprotkb:Q9Y371	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-2623095|uniprotkb:Q9H3Z0|uniprotkb:Q9NYA9|uniprotkb:Q9NR47|uniprotkb:Q5H8U5|ensembl:ENSP00000473267|uniprotkb:B4E182	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:shlb1_human(display_long)|uniprotkb:KIAA0491(gene name synonym)|uniprotkb:Bax-interacting factor 1(gene name synonym)|uniprotkb:SH3 domain-containing GRB2-like protein B1(gene name synonym)|uniprotkb:CGI-61(orf name)|uniprotkb:SH3GLB1(gene name)|psi-mi:SH3GLB1(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11529248|imex:IM-24995-722	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	refseq:NP_001193580.1|refseq:NP_001193581.1|refseq:NP_057093.1|go:"GO:0030496"(midbody)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032801"(receptor catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0048102"(autophagic cell death)|go:"GO:0090148"(membrane fission)|go:"GO:1903527"(positive regulation of membrane tubulation)|go:"GO:1903778"(protein localization to vacuolar membrane)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|go:"GO:2000786"(positive regulation of autophagosome assembly)|interpro:IPR001452(Src homology-3)|interpro:IPR004148(BAR)|interpro:IPR027267|interpro:IPR028503|interpro:IPR035695|interpro:IPR036028|mint:Q9Y371|rcsb pdb:6UP6|rcsb pdb:6UPN|ensembl:ENSG00000097033(gene)|ensembl:ENST00000370558(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0006915"(apoptotic process)|go:"GO:0008289"(lipid binding)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016241"(regulation of macroautophagy)|refseq:NP_001193582.1|dip:DIP-41970N|entrezgene/locuslink:51100(identity)	-	crc64:66699F37B0013088	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:HSs455W45ciZL56fJSPOIvfhUIw9606	intact-crc:8DBBD239374E6384|rigid:y/esqv3+RMBW2Zk3eJGXwnsBAZ0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38340	uniprotkb:Q9Y2D8	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-2212028|uniprotkb:B4DFE3|uniprotkb:J3KR02|uniprotkb:A8K8W0|uniprotkb:D3DT13|uniprotkb:Q6P2P8|uniprotkb:Q6ULS1|uniprotkb:Q7L168|uniprotkb:Q9UIX0|intact:EBI-10964529|ensembl:ENSP00000340279	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:adip_human(display_long)|uniprotkb:SSX2IP(gene name)|psi-mi:SSX2IP(display_short)|uniprotkb:KIAA0923(gene name synonym)|uniprotkb:Afadin DIL domain-interacting protein(gene name synonym)|uniprotkb:SSX2-interacting protein(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11529239|imex:IM-24995-721	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	refseq:XP_011538912.1|refseq:NP_001159765.1|refseq:NP_001159766.1|refseq:NP_001159767.1|refseq:NP_001159889.1|refseq:NP_054740.3|refseq:XP_005270484.1|refseq:XP_005270485.1|refseq:XP_006710394.1|refseq:XP_016855723.1|ensembl:ENSG00000117155(gene)|ensembl:ENST00000342203(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005912"(adherens junction)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031252"(cell leading edge)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0035735"(intraciliary transport involved in cilium assembly)|go:"GO:0036064"(ciliary basal body)|go:"GO:0060271"(cilium assembly)|go:"GO:2000145"(regulation of cell motility)|interpro:IPR021622|mint:Q9Y2D8|entrezgene/locuslink:117178(identity)	-	crc64:66699F37B0013088	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:E0VeMRF9SrpQKSJFP01XEbMjeF89606	intact-crc:FE4D6E6C511A5A1E|rigid:6qAMXpSLuBuvHe7iirMVkcK0K8o	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O75569	uniprotkb:P38732	intact:EBI-713955|ensembl:ENSP00000318176|uniprotkb:Q53G24|uniprotkb:Q6X7T5|uniprotkb:Q8NDK4|uniprotkb:A8K3I6	intact:EBI-24379|uniprotkb:D3DKT0|ensemblfungi:YHL039W	psi-mi:prkra_human(display_long)|uniprotkb:Protein activator of the interferon-induced protein kinase(gene name synonym)|uniprotkb:PKR-associated protein X(gene name synonym)|uniprotkb:PKR-associating protein X(gene name synonym)|uniprotkb:HSD-14(orf name)|uniprotkb:PRKRA(gene name)|psi-mi:PRKRA(display_short)|uniprotkb:RAX(gene name synonym)|uniprotkb:PACT(gene name synonym)|uniprotkb:HSD14(orf name)|uniprotkb:Protein kinase, interferon-inducible double-stranded RNA-dependent activator(gene name synonym)	psi-mi:efm1_yeast(display_long)|uniprotkb:EFM1(gene name)|psi-mi:EFM1(display_short)|uniprotkb:Elongation factor methyltransferase 1(gene name synonym)|uniprotkb:YHL039W(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11529314|imex:IM-24995-729	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006955"(immune response)|go:"GO:0008047"(enzyme activator activity)|ensembl:ENSG00000180228(gene)|ensembl:ENST00000325748(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030422"(production of siRNA involved in RNA interference)|go:"GO:0031054"(pre-miRNA processing)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035196"(production of miRNAs involved in gene silencing by miRNA)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042474"(middle ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:0050821"(protein stabilization)|go:"GO:0070578"(RISC-loading complex)|go:"GO:0070883"(pre-miRNA binding)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR032478|interpro:IPR033363|interpro:IPR044465|interpro:IPR044466|interpro:IPR044467|mint:O75569|rcsb pdb:2DIX|reactome:R-HSA-203927|reactome:R-HSA-426486|refseq:NP_001132989.1|refseq:NP_001132990.1|refseq:NP_003681.1|dip:DIP-41809N|entrezgene/locuslink:8575(identity)	refseq:NP_011824.1|sgd:S000001031|dip:DIP-6582N|mint:P38732|ensemblfungi:YHL039W(gene)|ensemblfungi:YHL039W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0018026"(peptidyl-lysine monomethylation)|go:"GO:0018027"(peptidyl-lysine dimethylation)|interpro:IPR001214(SET)|interpro:IPR017119(Ribosomal lysine methyltransferase 1)|interpro:IPR044432|sgd:YHL039W(identity)	-	-	crc64:84BC2D3A204D9D29	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:tZfziopZlC+1d3De97G3kDY+Tog9606	rogid:e5E4ijHZAIzzKWrxCzPqifR2v8U559292	intact-crc:41182971751A87F9|rigid:a/LTA+bxGClszC704i1ljQY/RaQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38703	uniprotkb:P63279	intact:EBI-10035|uniprotkb:Q6LD26|uniprotkb:D3DKR1|ensemblfungi:YHL003C	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	psi-mi:lag1_yeast(display_long)|uniprotkb:LAG1(gene name)|psi-mi:LAG1(display_short)|uniprotkb:Longevity assurance factor 1(gene name synonym)|uniprotkb:Longevity assurance protein 1(gene name synonym)|uniprotkb:Longevity assurance gene 1 protein(gene name synonym)|uniprotkb:Very-long-chain ceramide synthase LAG1(gene name synonym)|uniprotkb:YHL003C(locus name)	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11529305|imex:IM-24995-728	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011860.1|sgd:S000000995|ensemblfungi:YHL003C(gene)|ensemblfungi:YHL003C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016410"(N-acyltransferase activity)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:0050291"(sphingosine N-acyltransferase activity)|go:"GO:0061576"(acyl-CoA ceramide synthase complex)|interpro:IPR006634(TRAM, LAG1 and CLN8 homology)|interpro:IPR013599(TRAM1-like protein)|interpro:IPR016439(Longevity assurance, LAG1/LAC1)|reactome:R-SCE-1660661|dip:DIP-4393N|mint:P38703|sgd:YHL003C(identity)	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N|entrezgene/locuslink:7329(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:KCAjx/gXmy0oGd3aKgasDuFHJzw559292	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	intact-crc:4DAD722887737219|rigid:GzR5EKIvbhutmOl+4ZPKiZuCbPE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96BA8	uniprotkb:P38695	intact:EBI-6942903|ensembl:ENSP00000481956|intact:MINT-268046|intact:MINT-8162577|uniprotkb:Q8N2D5|uniprotkb:Q96CP0	intact:EBI-8778|ensemblfungi:YHR096C|uniprotkb:D3DL46	psi-mi:cr3l1_human(display_long)|uniprotkb:CREB3L1(gene name)|psi-mi:CREB3L1(display_short)|uniprotkb:OASIS(gene name synonym)|uniprotkb:PSEC0238(orf name)|uniprotkb:Old astrocyte specifically-induced substance(gene name synonym)	psi-mi:hxt5_yeast(display_long)|uniprotkb:YHR096C(locus name)|uniprotkb:HXT5(gene name)|psi-mi:HXT5(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11529295|imex:IM-24995-727	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157613(gene)|ensembl:ENST00000621158(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0070278"(extracellular matrix constituent secretion)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029805|mint:Q96BA8|reactome:R-HSA-8874211|refseq:NP_443086.1|entrezgene/locuslink:90993(identity)	ensemblfungi:YHR096C(gene)|ensemblfungi:YHR096C_mRNA(transcript)|go:"GO:0005351"("carbohydrate:proton symporter activity")|go:"GO:0005355"(glucose transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005353"(fructose transmembrane transporter activity)|go:"GO:0008643"(carbohydrate transport)|go:"GO:0008645"(hexose transmembrane transport)|go:"GO:0015578"(mannose transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|go:"GO:1904659"(glucose transmembrane transport)|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259|refseq:NP_011964.1|sgd:S000001138|mint:P38695|dip:DIP-5594N|sgd:YHR096C(identity)	-	comment:mint|function:"Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE"	crc64:6906721BAC1A5F87	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:sMWUFmBeBBCO+T0Y2CuB/un1lBg9606	rogid:aZGrWmUu+AZ4G6qmTG+Z+p6i7hs559292	intact-crc:41431542A3F1637A|rigid:clZKqOoiykAaQU0HwL5bwgX/Tt0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38695	uniprotkb:Q8N6L0	intact:EBI-8778|ensemblfungi:YHR096C|uniprotkb:D3DL46	intact:EBI-749265|uniprotkb:Q96MC3|ensembl:ENSP00000404220	psi-mi:hxt5_yeast(display_long)|uniprotkb:YHR096C(locus name)|uniprotkb:HXT5(gene name)|psi-mi:HXT5(display_short)	psi-mi:kash5_human(display_long)|uniprotkb:KASH5(gene name)|psi-mi:KASH5(display_short)|uniprotkb:CCDC155(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 155(gene name synonym)|uniprotkb:KASH domain-containing protein 5(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11529286|imex:IM-24995-726	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YHR096C(gene)|ensemblfungi:YHR096C_mRNA(transcript)|go:"GO:0005351"("carbohydrate:proton symporter activity")|go:"GO:0005355"(glucose transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005353"(fructose transmembrane transporter activity)|go:"GO:0008643"(carbohydrate transport)|go:"GO:0008645"(hexose transmembrane transport)|go:"GO:0015578"(mannose transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|go:"GO:1904659"(glucose transmembrane transport)|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259|refseq:NP_011964.1|sgd:S000001138|mint:P38695|dip:DIP-5594N|sgd:YHR096C(identity)	refseq:NP_653289.3|ensembl:ENSG00000161609(gene)|ensembl:ENST00000447857(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034397"(telomere localization)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051225"(spindle assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0090172"(microtubule cytoskeleton organization involved in homologous chromosome segregation)|go:"GO:0090220"(chromosome localization to nuclear envelope involved in homologous chromosome segregation)|go:"GO:0090619"(meiotic spindle pole)|interpro:IPR011992(EF-Hand type)|interpro:IPR028168|interpro:IPR028170|interpro:IPR039508|mint:Q8N6L0|rcsb pdb:6R2I|rcsb pdb:6WMF|entrezgene/locuslink:147872(identity)	-	crc64:6906721BAC1A5F87	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:aZGrWmUu+AZ4G6qmTG+Z+p6i7hs559292	rogid:Wl9L7AcvDHCZuKjYLn8QgGIbZTc9606	intact-crc:1BEE89DD76F1FCD6|rigid:t8lYMWTXrz7eoxfyij3jYiVMNaM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q99259	uniprotkb:P38635	intact:EBI-743184|ensembl:ENSP00000350928|uniprotkb:Q53TQ7|uniprotkb:Q9BU91|uniprotkb:Q9UHH4|uniprotkb:Q49AK1	intact:EBI-2045554|uniprotkb:D6VTQ5|ensemblfungi:YFR025C	psi-mi:dce1_human(display_long)|uniprotkb:Glutamate decarboxylase 67 kDa isoform(gene name synonym)|uniprotkb:67 kDa glutamic acid decarboxylase(gene name synonym)|uniprotkb:GAD1(gene name)|psi-mi:GAD1(display_short)|uniprotkb:GAD(gene name synonym)|uniprotkb:GAD67(gene name synonym)	psi-mi:his9_yeast(display_long)|uniprotkb:YFR025C(locus name)|uniprotkb:HIS2(gene name)|psi-mi:HIS2(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11529277|imex:IM-24995-725	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000808.2|refseq:NP_038473.2|ensembl:ENSG00000128683(gene)|ensembl:ENST00000358196(transcript)|go:"GO:0004351"(glutamate decarboxylase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0060077"(inhibitory synapse)|go:"GO:0061202"(clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006538"(glutamate catabolic process)|go:"GO:0006540"(glutamate decarboxylation to succinate)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0009449"(gamma-aminobutyric acid biosynthetic process)|go:"GO:0012506"(vesicle membrane)|go:"GO:0016595"(glutamate binding)|go:"GO:0018352"(protein-pyridoxal-5-phosphate linkage)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0035176"(social behavior)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0042136"(neurotransmitter biosynthetic process)|go:"GO:0042493"|go:"GO:0043679"(axon terminus)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048786"(presynaptic active zone)|interpro:IPR002129(Pyridoxal phosphate-dependent decarboxylase)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR021115|mint:Q99259|rcsb pdb:2OKJ|rcsb pdb:3VP6|reactome:R-HSA-888568|reactome:R-HSA-888590|reactome:R-HSA-9022927|refseq:XP_011509224.1|refseq:XP_005246501.1|refseq:XP_016859245.1|refseq:XP_016859247.1|dip:DIP-29292N|entrezgene/locuslink:2571(identity)	refseq:NP_116681.1|sgd:S000001921|interpro:IPR010140(Histidinol phosphate phosphatase, HisJ)|interpro:IPR004013(PHP, C-terminal)|interpro:IPR016195(Polymerase and histidinol phosphatase-like)|mint:P38635|ensemblfungi:YFR025C(gene)|ensemblfungi:YFR025C_mRNA(transcript)|go:"GO:0000105"(histidine biosynthetic process)|go:"GO:0004401"(histidinol-phosphatase activity)|go:"GO:0005737"(cytoplasm)|sgd:YFR025C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:tFlqx11D9m3HofJUdpZynm2jKIQ9606	rogid:3gGqFDbJWtM4it1O4HJjk6KoTL4559292	intact-crc:BD48EA80AEBA0A7A|rigid:RPeVitSwH4UGTGHiXyA/r5yXpQU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8WW34-2	uniprotkb:P38736	intact:EBI-11528917|ensembl:ENSP00000369959	intact:EBI-24365|uniprotkb:D3DKT7|ensemblfungi:YHL031C	psi-mi:q8ww34-2(display_long)|uniprotkb:TMEM239(gene name)|psi-mi:TMEM239(display_short)	psi-mi:gosr1_yeast(display_long)|uniprotkb:Golgi SNARE protein 1(gene name synonym)|uniprotkb:GOS1(gene name)|psi-mi:GOS1(display_short)|uniprotkb:Protein transport protein GOS1(gene name synonym)|uniprotkb:YHL031C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11529363|imex:IM-24995-734	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-9675724(isoform-parent)|uniprotkb:Q8WW34-2(isoform-parent)|ensembl:ENSG00000198326(gene)|ensembl:ENST00000380585(transcript)|entrezgene/locuslink:100288797(identity)	refseq:NP_011832.1|sgd:S000001023|reactome:R-SCE-6811438|dip:DIP-2490N|reactome:R-SCE-6807878|ensemblfungi:YHL031C(gene)|ensemblfungi:YHL031C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005797"(Golgi medial cisterna)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0048193"(Golgi vesicle transport)|go:"GO:0048209"(regulation of vesicle targeting, to, from or within Golgi)|interpro:IPR023601|go:"GO:0006906"(vesicle fusion)|sgd:YHL031C(identity)	-	isoform-comment:No experimental confirmation available.	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:1VqWIwPpWs6WjW8eDoJUHz2pegw9606	rogid:pAzDzV46XXzIOB4p/oc1PlMc54E559292	intact-crc:AAF126EEC43D61C8|rigid:JPdB/sKMG5ILWTWJY5RggSkGkzw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38736	uniprotkb:Q8N6L0	intact:EBI-24365|uniprotkb:D3DKT7|ensemblfungi:YHL031C	intact:EBI-749265|uniprotkb:Q96MC3|ensembl:ENSP00000404220	psi-mi:gosr1_yeast(display_long)|uniprotkb:Golgi SNARE protein 1(gene name synonym)|uniprotkb:GOS1(gene name)|psi-mi:GOS1(display_short)|uniprotkb:Protein transport protein GOS1(gene name synonym)|uniprotkb:YHL031C(locus name)	psi-mi:kash5_human(display_long)|uniprotkb:KASH5(gene name)|psi-mi:KASH5(display_short)|uniprotkb:CCDC155(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 155(gene name synonym)|uniprotkb:KASH domain-containing protein 5(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11529354|imex:IM-24995-733	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011832.1|sgd:S000001023|reactome:R-SCE-6811438|dip:DIP-2490N|reactome:R-SCE-6807878|ensemblfungi:YHL031C(gene)|ensemblfungi:YHL031C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005797"(Golgi medial cisterna)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0048193"(Golgi vesicle transport)|go:"GO:0048209"(regulation of vesicle targeting, to, from or within Golgi)|interpro:IPR023601|go:"GO:0006906"(vesicle fusion)|sgd:YHL031C(identity)	refseq:NP_653289.3|ensembl:ENSG00000161609(gene)|ensembl:ENST00000447857(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034397"(telomere localization)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051225"(spindle assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0090172"(microtubule cytoskeleton organization involved in homologous chromosome segregation)|go:"GO:0090220"(chromosome localization to nuclear envelope involved in homologous chromosome segregation)|go:"GO:0090619"(meiotic spindle pole)|interpro:IPR011992(EF-Hand type)|interpro:IPR028168|interpro:IPR028170|interpro:IPR039508|mint:Q8N6L0|rcsb pdb:6R2I|rcsb pdb:6WMF|entrezgene/locuslink:147872(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:pAzDzV46XXzIOB4p/oc1PlMc54E559292	rogid:Wl9L7AcvDHCZuKjYLn8QgGIbZTc9606	intact-crc:FEB6650641E602AA|rigid:AwEJ1X9wku/5sYyHJ7+ja3HtWaQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12846	uniprotkb:P38736	intact:EBI-744942|uniprotkb:Q15525|ensembl:ENSP00000317714|uniprotkb:Q6FHE8|uniprotkb:A8MXY0	intact:EBI-24365|uniprotkb:D3DKT7|ensemblfungi:YHL031C	psi-mi:stx4_human(display_long)|uniprotkb:Renal carcinoma antigen NY-REN-31(gene name synonym)|uniprotkb:STX4(gene name)|psi-mi:STX4(display_short)|uniprotkb:STX4A(gene name synonym)	psi-mi:gosr1_yeast(display_long)|uniprotkb:Golgi SNARE protein 1(gene name synonym)|uniprotkb:GOS1(gene name)|psi-mi:GOS1(display_short)|uniprotkb:Protein transport protein GOS1(gene name synonym)|uniprotkb:YHL031C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11529345|imex:IM-24995-732	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000103496(gene)|refseq:NP_004595.2|ensembl:ENST00000313843(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0000322"(storage vacuole)|go:"GO:0002639"(positive regulation of immunoglobulin production)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005768"(endosome)|go:"GO:0005773"(vacuole)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006887"(exocytosis)|go:"GO:0006906"(vesicle fusion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016230"(sphingomyelin phosphodiesterase activator activity)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0032589"(neuron projection membrane)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035493"(SNARE complex assembly)|go:"GO:0035749"(myelin sheath adaxonal region)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0036477"(somatodendritic compartment)|go:"GO:0042581"(specific granule)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043197"(dendritic spine)|go:"GO:0043219"(lateral loop)|go:"GO:0043311"(positive regulation of eosinophil degranulation)|go:"GO:0045202"(synapse)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0048278"(vesicle docking)|go:"GO:0048284"(organelle fusion)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048787"(presynaptic active zone membrane)|go:"GO:0050921"(positive regulation of chemotaxis)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1902041"(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1903575"(cornified envelope assembly)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|reactome:R-HSA-114516|reactome:R-HSA-1236974|reactome:R-HSA-1445148|reactome:R-HSA-199992|reactome:R-HSA-449836|interpro:IPR006011(Syntaxin, N-terminal)|refseq:NP_001259025.1|entrezgene/locuslink:6810(identity)	refseq:NP_011832.1|sgd:S000001023|reactome:R-SCE-6811438|dip:DIP-2490N|reactome:R-SCE-6807878|ensemblfungi:YHL031C(gene)|ensemblfungi:YHL031C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005797"(Golgi medial cisterna)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0048193"(Golgi vesicle transport)|go:"GO:0048209"(regulation of vesicle targeting, to, from or within Golgi)|interpro:IPR023601|go:"GO:0006906"(vesicle fusion)|sgd:YHL031C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:NvOLGIGe/XO2aDPSpdPzrtKniZY9606	rogid:pAzDzV46XXzIOB4p/oc1PlMc54E559292	intact-crc:028403323FC61CF5|rigid:szKyYXHC1lWBdl3DK2CWB+V8uW8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9H898-2	uniprotkb:P38732	intact:EBI-11529334|ensembl:ENSP00000319785	intact:EBI-24379|uniprotkb:D3DKT0|ensemblfungi:YHL039W	psi-mi:q9h898-2(display_long)|uniprotkb:ZMAT4(gene name)|psi-mi:ZMAT4(display_short)	psi-mi:efm1_yeast(display_long)|uniprotkb:EFM1(gene name)|psi-mi:EFM1(display_short)|uniprotkb:Elongation factor methyltransferase 1(gene name synonym)|uniprotkb:YHL039W(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11529332|imex:IM-24995-731	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000165061(gene)|ensembl:ENST00000315769(transcript)|intact:EBI-2548542(isoform-parent)|uniprotkb:Q9H898-2(isoform-parent)|entrezgene/locuslink:79698(identity)	refseq:NP_011824.1|sgd:S000001031|dip:DIP-6582N|mint:P38732|ensemblfungi:YHL039W(gene)|ensemblfungi:YHL039W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0018026"(peptidyl-lysine monomethylation)|go:"GO:0018027"(peptidyl-lysine dimethylation)|interpro:IPR001214(SET)|interpro:IPR017119(Ribosomal lysine methyltransferase 1)|interpro:IPR044432|sgd:YHL039W(identity)	-	-	crc64:84BC2D3A204D9D29	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:LOS8TGoD/X97NtzSXSQ3uppdS6s9606	rogid:e5E4ijHZAIzzKWrxCzPqifR2v8U559292	intact-crc:4CE4CFEAE3036354|rigid:yR7MxZvdtOouBGQrd9CwGxb10Ro	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38432	uniprotkb:P38732	intact:EBI-945751|uniprotkb:B2R931|ensembl:ENSP00000240316	intact:EBI-24379|uniprotkb:D3DKT0|ensemblfungi:YHL039W	psi-mi:coil_human(display_long)|uniprotkb:COIL(gene name)|psi-mi:COIL(display_short)|uniprotkb:CLN80(gene name synonym)|uniprotkb:p80-coilin(gene name synonym)	psi-mi:efm1_yeast(display_long)|uniprotkb:EFM1(gene name)|psi-mi:EFM1(display_short)|uniprotkb:Elongation factor methyltransferase 1(gene name synonym)|uniprotkb:YHL039W(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11529323|imex:IM-24995-730	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004636.1|dip:DIP-38503N|ensembl:ENSG00000121058(gene)|ensembl:ENST00000240316(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0015030"(Cajal body)|go:"GO:0016020"(membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0030619"(U1 snRNA binding)|go:"GO:0030620"(U2 snRNA binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR024822|interpro:IPR031722|mint:P38432|entrezgene/locuslink:8161(identity)	refseq:NP_011824.1|sgd:S000001031|dip:DIP-6582N|mint:P38732|ensemblfungi:YHL039W(gene)|ensemblfungi:YHL039W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0018026"(peptidyl-lysine monomethylation)|go:"GO:0018027"(peptidyl-lysine dimethylation)|interpro:IPR001214(SET)|interpro:IPR017119(Ribosomal lysine methyltransferase 1)|interpro:IPR044432|sgd:YHL039W(identity)	-	-	crc64:84BC2D3A204D9D29	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:hd5p6AbyA/GYNEeca99Mdb41qM09606	rogid:e5E4ijHZAIzzKWrxCzPqifR2v8U559292	intact-crc:AABCC2A377247BA0|rigid:g8DjAPiY7s/Ez4qEL6eO+HZ0ojI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q7L190	uniprotkb:P38744	intact:EBI-710457|intact:EBI-28975079|ensembl:ENSP00000335306|uniprotkb:Q9H9N5|uniprotkb:Q9NVI6|uniprotkb:A8K4M7	intact:EBI-13396|uniprotkb:D3DKR5|ensemblfungi:YHL018W	psi-mi:dppa4_human(display_long)|uniprotkb:DPPA4(gene name)|psi-mi:DPPA4(display_short)	psi-mi:phs_yeast(display_long)|uniprotkb:4-alpha-hydroxy-tetrahydropterin dehydratase(gene name synonym)|uniprotkb:Pterin carbinolamine dehydratase(gene name synonym)|uniprotkb:YHL018W(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11529408|imex:IM-24995-739	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060659.3|mint:Q7L190|reactome:R-HSA-2892247|ensembl:ENSG00000121570(gene)|ensembl:ENST00000335658(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0048731"(system development)|go:"GO:0060484"(lung-associated mesenchyme development)|interpro:IPR025891|interpro:IPR025892|interpro:IPR039590|interpro:IPR039836|ensembl:ENSP00000335306|entrezgene/locuslink:55211(identity)	refseq:NP_011845.1|sgd:S000001010|interpro:IPR036428|interpro:IPR001533(Transcriptional coactivator/pterin dehydratase)|ensemblfungi:YHL018W(gene)|ensemblfungi:YHL018W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0008124"(4-alpha-hydroxytetrahydrobiopterin dehydratase activity)|dip:DIP-1872N|reactome:R-SCE-8964208|sgd:YHL018W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:WKqQ0ipAAfKsDRuXJhtTWJcROdc9606	rogid:7+JuLX1wFw/tkE4NcSCTK62b4DU559292	intact-crc:FE92870E754CF9D0|rigid:v9KswGtAu+XifBD3ie3kecZgK+w	false	sufficient binding region:11-304	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q5JR59-3	uniprotkb:P38744	intact:EBI-11522433|ensembl:ENSP00000370186	intact:EBI-13396|uniprotkb:D3DKR5|ensemblfungi:YHL018W	psi-mi:q5jr59-3(display_long)|uniprotkb:MTUS2(gene name)|psi-mi:MTUS2(display_short)|uniprotkb:CAZIP(gene name synonym)|uniprotkb:Cardiac zipper protein(gene name synonym)|uniprotkb:KIAA0774(gene name synonym)|uniprotkb:Microtubule plus-end tracking protein TIP150(gene name synonym)|uniprotkb:TIP150(gene name synonym)	psi-mi:phs_yeast(display_long)|uniprotkb:4-alpha-hydroxy-tetrahydropterin dehydratase(gene name synonym)|uniprotkb:Pterin carbinolamine dehydratase(gene name synonym)|uniprotkb:YHL018W(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11529399|imex:IM-24995-738	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000132938(gene)|ensembl:ENST00000380808(transcript)|intact:EBI-742948(isoform-parent)|uniprotkb:Q5JR59-3(isoform-parent)|entrezgene/locuslink:23281(identity)	refseq:NP_011845.1|sgd:S000001010|interpro:IPR036428|interpro:IPR001533(Transcriptional coactivator/pterin dehydratase)|ensemblfungi:YHL018W(gene)|ensemblfungi:YHL018W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0008124"(4-alpha-hydroxytetrahydrobiopterin dehydratase activity)|dip:DIP-1872N|reactome:R-SCE-8964208|sgd:YHL018W(identity)	-	isoform-comment:No experimental confirmation available.	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:npId9tC7VoLN/jteoBiRbSYChPs9606	rogid:7+JuLX1wFw/tkE4NcSCTK62b4DU559292	intact-crc:B026CB3A77D6FD80|rigid:OqlY1umJIVGHXTYTVzd2M3kGP9k	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38744	uniprotkb:Q02363	intact:EBI-13396|uniprotkb:D3DKR5|ensemblfungi:YHL018W	intact:EBI-713450|ensembl:ENSP00000234091|ensembl:ENSP00000379585|ensembl:ENSP00000385465	psi-mi:phs_yeast(display_long)|uniprotkb:4-alpha-hydroxy-tetrahydropterin dehydratase(gene name synonym)|uniprotkb:Pterin carbinolamine dehydratase(gene name synonym)|uniprotkb:YHL018W(locus name)	psi-mi:id2_human(display_long)|uniprotkb:Inhibitor of DNA binding 2(gene name synonym)|uniprotkb:ID2(gene name)|psi-mi:ID2(display_short)|uniprotkb:BHLHB26(gene name synonym)|uniprotkb:Class B basic helix-loop-helix protein 26(gene name synonym)|uniprotkb:Inhibitor of differentiation 2(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11529390|imex:IM-24995-737	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011845.1|sgd:S000001010|interpro:IPR036428|interpro:IPR001533(Transcriptional coactivator/pterin dehydratase)|ensemblfungi:YHL018W(gene)|ensemblfungi:YHL018W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0008124"(4-alpha-hydroxytetrahydrobiopterin dehydratase activity)|dip:DIP-1872N|reactome:R-SCE-8964208|sgd:YHL018W(identity)	ensembl:ENSG00000115738(gene)|ensembl:ENST00000234091(transcript)|ensembl:ENST00000331129(transcript)|ensembl:ENST00000396290(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000791"(euchromatin)|go:"GO:0003166"(bundle of His development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007507"(heart development)|go:"GO:0007623"(circadian rhythm)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0030154"(cell differentiation)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033598"(mammary gland epithelial cell proliferation)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0043353"(enucleate erythrocyte differentiation)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0045578"(negative regulation of B cell differentiation)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045651"(positive regulation of macrophage differentiation)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0045777"(positive regulation of blood pressure)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0048663"(neuron fate commitment)|go:"GO:0048711"(positive regulation of astrocyte differentiation)|go:"GO:0051148"(negative regulation of muscle cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0061030"(epithelial cell differentiation involved in mammary gland alveolus development)|go:"GO:0061031"(endodermal digestive tract morphogenesis)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0071931"(positive regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0090398"(cellular senescence)|go:"GO:0140416"(transcription regulator inhibitor activity)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000177"(regulation of neural precursor cell proliferation)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR026052|interpro:IPR036638|mint:Q02363|rcsb pdb:4AYA|reactome:R-HSA-9031628|refseq:NP_002157.2|dip:DIP-46874N|entrezgene/locuslink:3398(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:7+JuLX1wFw/tkE4NcSCTK62b4DU559292	rogid:zKX4mIq64fyS8DVPGQNeL7+c50w9606	intact-crc:79809A4AC94789B8|rigid:oNdc+G4sFcPRPhFkvBSc240INoY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O76083-2	uniprotkb:P38744	intact:EBI-11524542|ensembl:ENSP00000335242	intact:EBI-13396|uniprotkb:D3DKR5|ensemblfungi:YHL018W	psi-mi:o76083-2(display_long)|uniprotkb:PDE9A(gene name)|psi-mi:PDE9A(display_short)	psi-mi:phs_yeast(display_long)|uniprotkb:4-alpha-hydroxy-tetrahydropterin dehydratase(gene name synonym)|uniprotkb:Pterin carbinolamine dehydratase(gene name synonym)|uniprotkb:YHL018W(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11529381|imex:IM-24995-736	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-742764(isoform-parent)|ensembl:ENSG00000160191(gene)|ensembl:ENST00000335512(transcript)|uniprotkb:O76083-2(isoform-parent)|entrezgene/locuslink:5152(identity)	refseq:NP_011845.1|sgd:S000001010|interpro:IPR036428|interpro:IPR001533(Transcriptional coactivator/pterin dehydratase)|ensemblfungi:YHL018W(gene)|ensemblfungi:YHL018W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0008124"(4-alpha-hydroxytetrahydrobiopterin dehydratase activity)|dip:DIP-1872N|reactome:R-SCE-8964208|sgd:YHL018W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:nTzgeYGOwTM/7VJUgxSnlnDiCFo9606	rogid:7+JuLX1wFw/tkE4NcSCTK62b4DU559292	intact-crc:637E02B5B60429A6|rigid:SeKXelifYejMqVdZovbthoJLm68	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96BA8	uniprotkb:P38736	intact:EBI-6942903|ensembl:ENSP00000481956|intact:MINT-268046|intact:MINT-8162577|uniprotkb:Q8N2D5|uniprotkb:Q96CP0	intact:EBI-24365|uniprotkb:D3DKT7|ensemblfungi:YHL031C	psi-mi:cr3l1_human(display_long)|uniprotkb:CREB3L1(gene name)|psi-mi:CREB3L1(display_short)|uniprotkb:OASIS(gene name synonym)|uniprotkb:PSEC0238(orf name)|uniprotkb:Old astrocyte specifically-induced substance(gene name synonym)	psi-mi:gosr1_yeast(display_long)|uniprotkb:Golgi SNARE protein 1(gene name synonym)|uniprotkb:GOS1(gene name)|psi-mi:GOS1(display_short)|uniprotkb:Protein transport protein GOS1(gene name synonym)|uniprotkb:YHL031C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11529372|imex:IM-24995-735	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157613(gene)|ensembl:ENST00000621158(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0070278"(extracellular matrix constituent secretion)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029805|mint:Q96BA8|reactome:R-HSA-8874211|refseq:NP_443086.1|entrezgene/locuslink:90993(identity)	refseq:NP_011832.1|sgd:S000001023|reactome:R-SCE-6811438|dip:DIP-2490N|reactome:R-SCE-6807878|ensemblfungi:YHL031C(gene)|ensemblfungi:YHL031C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005797"(Golgi medial cisterna)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0048193"(Golgi vesicle transport)|go:"GO:0048209"(regulation of vesicle targeting, to, from or within Golgi)|interpro:IPR023601|go:"GO:0006906"(vesicle fusion)|sgd:YHL031C(identity)	-	comment:mint|function:"Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE"	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:sMWUFmBeBBCO+T0Y2CuB/un1lBg9606	rogid:pAzDzV46XXzIOB4p/oc1PlMc54E559292	intact-crc:2F83C6740D083E89|rigid:nyLw3FZJsmx2KHNyGUz8o3CuFSk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38763	uniprotkb:Q8IYF3-3	intact:EBI-24475|uniprotkb:D3DKW8|ensemblfungi:YHR022C	intact:EBI-11523345|ensembl:ENSP00000363453	psi-mi:yhi2_yeast(display_long)|uniprotkb:YHR022C(locus name)	psi-mi:q8iyf3-3(display_long)|uniprotkb:TEX11(gene name)|psi-mi:TEX11(display_short)|uniprotkb:Protein ZIP4 homolog(gene name synonym)|uniprotkb:ZIP4(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11529428|imex:IM-24995-741	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011887.1|sgd:S000001064|dip:DIP-1876N|ensemblfungi:YHR022C(gene)|ensemblfungi:YHR022C_mRNA(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0012505"(endomembrane system)|interpro:IPR001806(Ras GTPase)|interpro:IPR027417|reactome:R-SCE-6811440|reactome:R-SCE-8873719|reactome:R-SCE-8876198|sgd:YHR022C(identity)	ensembl:ENSG00000120498(gene)|ensembl:ENST00000374333(transcript)|intact:EBI-742397(isoform-parent)|uniprotkb:Q8IYF3-3(isoform-parent)|entrezgene/locuslink:56159(identity)	-	crc64:8A4A500681EF3D74	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:jcjAXgGlLpgsG473/s41ALnbUQo559292	rogid:PUAMFmnm5ZV2rnJ1rhm9ZeRCixg9606	intact-crc:DD9D8F623BAD0C23|rigid:8zgdx4i3Cj+n7krc8HseIoEhcHc	false	-	sufficient binding region:9-925	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P10644	uniprotkb:P38756	intact:EBI-476431|uniprotkb:Q567S7|uniprotkb:K7ER48|ensembl:ENSP00000351410|ensembl:ENSP00000376475|ensembl:ENSP00000445625|ensembl:ENSP00000464977|ensembl:ENSP00000466459	intact:EBI-24431|uniprotkb:D3DKU6|ensemblfungi:YHR003C	psi-mi:kap0_human(display_long)|uniprotkb:Tissue-specific extinguisher 1(gene name synonym)|uniprotkb:PRKAR1A(gene name)|psi-mi:PRKAR1A(display_short)|uniprotkb:PKR1(gene name synonym)|uniprotkb:PRKAR1(gene name synonym)|uniprotkb:TSE1(gene name synonym)	psi-mi:tcd1_yeast(display_long)|uniprotkb:TCD1(gene name)|psi-mi:TCD1(display_short)|uniprotkb:"t(6)A37 dehydratase 1"(gene name synonym)|uniprotkb:YHR003C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11529419|imex:IM-24995-740	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002725.1|refseq:NP_997636.1|refseq:NP_997637.1|refseq:XP_011523285.1|refseq:XP_011523286.1|refseq:XP_011523287.1|refseq:NP_001263218.1|refseq:NP_001263219.1|refseq:NP_001265362.1|dip:DIP-34368N|ensembl:ENSG00000108946(gene)|ensembl:ENST00000358598(transcript)|ensembl:ENST00000392711(transcript)|ensembl:ENST00000536854(transcript)|ensembl:ENST00000586397(transcript)|ensembl:ENST00000589228(transcript)|go:"GO:0001707"(mesoderm formation)|go:"GO:0004862"(cAMP-dependent protein kinase inhibitor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005771"(multivesicular body)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005952"(cAMP-dependent protein kinase complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007143"(female meiotic nuclear division)|go:"GO:0008603"(cAMP-dependent protein kinase regulator activity)|go:"GO:0010738"(regulation of protein kinase A signaling)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030552"(cAMP binding)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043949"(regulation of cAMP-mediated signaling)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045835"(negative regulation of meiotic nuclear division)|go:"GO:0046007"(negative regulation of activated T cell proliferation)|go:"GO:0060038"(cardiac muscle cell proliferation)|go:"GO:0097224"(sperm connecting piece)|go:"GO:0097546"(ciliary base)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:2000480"(negative regulation of cAMP-dependent protein kinase activity)|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR003117(cAMP-dependent protein kinase, regulatory subunit, type I/II alpha/beta)|interpro:IPR012198(cAMP-dependent protein kinase regulatory subunit)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR018488|rcsb pdb:5KJZ|reactome:R-HSA-163615|reactome:R-HSA-164378|reactome:R-HSA-180024|reactome:R-HSA-381676|reactome:R-HSA-432040|reactome:R-HSA-442720|reactome:R-HSA-5610787|reactome:R-HSA-9660821|reactome:R-HSA-9664323|reactome:R-HSA-983231|interpro:IPR018490|mint:P10644|rcsb pdb:5KJX|rcsb pdb:5KJY|entrezgene/locuslink:5573(identity)	refseq:NP_011866.1|sgd:S000001045|dip:DIP-4417N|mint:P38756|ensemblfungi:YHR003C(gene)|ensemblfungi:YHR003C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0008641"(ubiquitin-like modifier activating enzyme activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0061503"(tRNA threonylcarbamoyladenosine dehydratase)|go:"GO:0061504"(cyclic threonylcarbamoyladenosine biosynthetic process)|interpro:IPR000594(UBA/THIF-type NAD/FAD binding fold)|interpro:IPR035985|sgd:YHR003C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:dUZaCJQnC0KZEG4pccIqoT066VY9606	rogid:Mce7jBtBDJ9bSrw+cQDCbhK8DvY559292	intact-crc:377B97C272439B39|rigid:OXtZ/T6SUL0umW5fFMkbi7YCawM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96BA8	uniprotkb:P38775	intact:EBI-6942903|ensembl:ENSP00000481956|intact:MINT-268046|intact:MINT-8162577|uniprotkb:Q8N2D5|uniprotkb:Q96CP0	intact:EBI-24520|uniprotkb:D3DKZ3|ensemblfungi:YHR045W	psi-mi:cr3l1_human(display_long)|uniprotkb:CREB3L1(gene name)|psi-mi:CREB3L1(display_short)|uniprotkb:OASIS(gene name synonym)|uniprotkb:PSEC0238(orf name)|uniprotkb:Old astrocyte specifically-induced substance(gene name synonym)	psi-mi:yhk5_yeast(display_long)|uniprotkb:YHR045W(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11529470|imex:IM-24995-745	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157613(gene)|ensembl:ENST00000621158(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0070278"(extracellular matrix constituent secretion)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029805|mint:Q96BA8|reactome:R-HSA-8874211|refseq:NP_443086.1|entrezgene/locuslink:90993(identity)	sgd:S000001087|refseq:NP_011911.1|dip:DIP-5587N|mint:P38775|ensemblfungi:YHR045W(gene)|ensemblfungi:YHR045W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0016021"(integral component of membrane)|sgd:YHR045W(identity)	-	comment:mint|function:"Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE"	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:sMWUFmBeBBCO+T0Y2CuB/un1lBg9606	rogid:DIfjsK4iO1b4tmBBj9gsbfGBAoE559292	intact-crc:3F8820F2C2C13539|rigid:AlqmBVYU0BvJlGUq9nEYs5yqXZI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UJW9	uniprotkb:P38770	intact:EBI-748621|uniprotkb:Q96CQ2|uniprotkb:B3KQB3|ensembl:ENSP00000325414|ensembl:ENSP00000375882	intact:EBI-24507|uniprotkb:D3DKY3|ensemblfungi:YHR036W	psi-mi:srtd3_human(display_long)|uniprotkb:Replication protein-binding trans-activator(gene name synonym)|uniprotkb:SERTAD3(gene name)|psi-mi:SERTAD3(display_short)|uniprotkb:RBT1(gene name synonym)	psi-mi:brl1_yeast(display_long)|uniprotkb:BRL1(gene name)|psi-mi:BRL1(display_short)|uniprotkb:BRR6-like protein 1(gene name synonym)|uniprotkb:YHR036W(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11529461|imex:IM-24995-744	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006723242.1|refseq:NP_037500.2|refseq:NP_976219.1|refseq:XP_005258889.1|ensembl:ENSG00000167565(gene)|ensembl:ENST00000322354(transcript)|ensembl:ENST00000392028(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR009263(SERTA)|interpro:IPR039585|entrezgene/locuslink:29946(identity)	refseq:NP_011901.1|sgd:S000001078|dip:DIP-5580N|mint:P38770|ensemblfungi:YHR036W(gene)|ensemblfungi:YHR036W_mRNA(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006998"(nuclear envelope organization)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0051028"(mRNA transport)|go:"GO:0055088"(lipid homeostasis)|interpro:IPR018767|interpro:IPR040202|sgd:YHR036W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:zraVKcqHA7SNRrMV50iyPK6O7ok9606	rogid:gLJXF3VREvr8+oW8HZYTfHDho4A559292	intact-crc:859A206E870BA20B|rigid:PAl3pboTff33jepoEJ8ViVlEyUk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38770	uniprotkb:Q9BXL8	intact:EBI-24507|uniprotkb:D3DKY3|ensemblfungi:YHR036W	intact:EBI-1773949|uniprotkb:Q8TB18|uniprotkb:Q9NWK7|ensembl:ENSP00000337226|ensembl:ENSP00000376369	psi-mi:brl1_yeast(display_long)|uniprotkb:BRL1(gene name)|psi-mi:BRL1(display_short)|uniprotkb:BRR6-like protein 1(gene name synonym)|uniprotkb:YHR036W(locus name)	psi-mi:cdca4_human(display_long)|uniprotkb:CDCA4(gene name)|psi-mi:CDCA4(display_short)|uniprotkb:HEPP(gene name synonym)|uniprotkb:Hematopoietic progenitor protein(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11529452|imex:IM-24995-743	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011901.1|sgd:S000001078|dip:DIP-5580N|mint:P38770|ensemblfungi:YHR036W(gene)|ensemblfungi:YHR036W_mRNA(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006998"(nuclear envelope organization)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0051028"(mRNA transport)|go:"GO:0055088"(lipid homeostasis)|interpro:IPR018767|interpro:IPR040202|sgd:YHR036W(identity)	refseq:NP_060425.2|refseq:NP_663747.1|ensembl:ENSG00000170779(gene)|ensembl:ENST00000336219(transcript)|ensembl:ENST00000392590(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0048096"|interpro:IPR009263(SERTA)|mint:Q9BXL8|entrezgene/locuslink:55038(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:gLJXF3VREvr8+oW8HZYTfHDho4A559292	rogid:sxwZ0Yw0uG+MjnhKtVv+8PHvPCo9606	intact-crc:298E383BE5ECE96E|rigid:X/OgNRGYdVkcb3UluzUCgcjpNdI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P63010-2	uniprotkb:P38769	intact:EBI-11529439|ensembl:ENSP00000482835|ensembl:ENSP00000483185	intact:EBI-24503|uniprotkb:D3DKY2|ensemblfungi:YHR035W	psi-mi:p63010-2(display_long)|uniprotkb:ADTB2(gene name synonym)|uniprotkb:AP105B(gene name synonym)|uniprotkb:Adaptor protein complex AP-2 subunit beta(gene name synonym)|uniprotkb:Adaptor-related protein complex 2 subunit beta(gene name synonym)|uniprotkb:Beta-2-adaptin(gene name synonym)|uniprotkb:Beta-adaptin(gene name synonym)|uniprotkb:CLAPB1(gene name synonym)|uniprotkb:Clathrin assembly protein complex 2 beta large chain(gene name synonym)|uniprotkb:AP2B1(gene name)|psi-mi:AP2B1(display_short)|uniprotkb:Plasma membrane adaptor HA2/AP2 adaptin beta subunit(gene name synonym)	psi-mi:nel1_yeast(display_long)|uniprotkb:NEL1(gene name)|psi-mi:NEL1(display_short)|uniprotkb:Non-ERES-localized SEC23 homolog 1(gene name synonym)|uniprotkb:YHR035W(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11529443|imex:IM-24995-742	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-432924(isoform-parent)|uniprotkb:P63010-2(isoform-parent)|ensembl:ENSG00000006125(gene)|ensembl:ENST00000610402(transcript)|ensembl:ENST00000618940(transcript)|entrezgene/locuslink:163(identity)	refseq:NP_011900.1|sgd:S000001077|dip:DIP-806N|mint:P38769|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:0090110"(COPII-coated vesicle cargo loading)|interpro:IPR006896(Sec23/Sec24 trunk region)|interpro:IPR036174|interpro:IPR036180|interpro:IPR036465|interpro:IPR037364|ensemblfungi:YHR035W_mRNA(transcript)|ensemblfungi:YHR035W(gene)|sgd:YHR035W(identity)	-	-	crc64:C42D24351D4FA75D	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:RpFHKbLgdxGqagTUoCCgQ2W+9nw9606	rogid:qiEwgSjz+4y1ObyBwCewGx9/NPc559292	intact-crc:8181B24ADBF9F86A|rigid:VzAs8w+jsKqLm4oY1Hmkgr7Iy8o	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8TAP6	uniprotkb:P38792	intact:EBI-742887|ensembl:ENSP00000262127|uniprotkb:Q658N5|uniprotkb:Q9H9U7|uniprotkb:B0YJB2|uniprotkb:B4DXG5|uniprotkb:B4DZW1	intact:EBI-1757|uniprotkb:D3DL18|ensemblfungi:YHR069C	psi-mi:cep76_human(display_long)|uniprotkb:CEP76(gene name)|psi-mi:CEP76(display_short)|uniprotkb:C18orf9(gene name synonym)	psi-mi:rrp4_yeast(display_long)|uniprotkb:RRP4(gene name)|psi-mi:RRP4(display_short)|uniprotkb:Ribosomal RNA-processing protein 4(gene name synonym)|uniprotkb:YHR069C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11529512|imex:IM-24995-749	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_079175.2|ensembl:ENSG00000101624(gene)|ensembl:ENST00000262127(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0046599"(regulation of centriole replication)|interpro:IPR028926|interpro:IPR038765|mint:Q8TAP6|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_001258918.1|entrezgene/locuslink:79959(identity)	refseq:NP_011936.1|sgd:S000001111|dip:DIP-5888N|mint:P38792|ensemblfungi:YHR069C(gene)|ensemblfungi:YHR069C_mRNA(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0071034"(CUT catabolic process)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071049"|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR004088(K Homology, type 1)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR025721|interpro:IPR026699|interpro:IPR036612|rcsb pdb:4IFD|rcsb pdb:4OO1|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5G06|rcsb pdb:5JEA|rcsb pdb:5K36|rcsb pdb:5OKZ|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-429958|reactome:R-SCE-450385|reactome:R-SCE-450513|reactome:R-SCE-6791226|sgd:YHR069C(identity)	-	-	crc64:0718A7ABF42E9B9B	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:fWzb8oIU35oVWomyDrf8u5sbxUk9606	rogid:ZgBS9xjR7jC96sAb0m63ElPvM7M559292	intact-crc:46A82F2AFBC5B4A6|rigid:FdK9E/hOr2p/p0E8zMPp69HfxXg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38792	uniprotkb:G5E962	intact:EBI-1757|uniprotkb:D3DL18|ensemblfungi:YHR069C	intact:EBI-11525615|ensembl:ENSP00000328177	psi-mi:rrp4_yeast(display_long)|uniprotkb:RRP4(gene name)|psi-mi:RRP4(display_short)|uniprotkb:Ribosomal RNA-processing protein 4(gene name synonym)|uniprotkb:YHR069C(locus name)	psi-mi:g5e962_human(display_long)|uniprotkb:hCG_1644200(orf name)|uniprotkb:MAGEA11(gene name)|psi-mi:MAGEA11(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11529501|imex:IM-24995-748	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011936.1|sgd:S000001111|dip:DIP-5888N|mint:P38792|ensemblfungi:YHR069C(gene)|ensemblfungi:YHR069C_mRNA(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0071034"(CUT catabolic process)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071049"|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR004088(K Homology, type 1)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR025721|interpro:IPR026699|interpro:IPR036612|rcsb pdb:4IFD|rcsb pdb:4OO1|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5G06|rcsb pdb:5JEA|rcsb pdb:5K36|rcsb pdb:5OKZ|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-429958|reactome:R-SCE-450385|reactome:R-SCE-450513|reactome:R-SCE-6791226|sgd:YHR069C(identity)	refseq:NP_001011544.1|ensembl:ENSG00000185247(gene)|ensembl:ENST00000333104(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016604"(nuclear body)|interpro:IPR002190(MAGE protein)|interpro:IPR021072|interpro:IPR030099|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|entrezgene/locuslink:4110(identity)	-	crc64:0718A7ABF42E9B9B	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:ZgBS9xjR7jC96sAb0m63ElPvM7M559292	rogid:sVB0aA6yibWUx/d2SE+pwpKKgtI9606	intact-crc:82EBDAB9C2D72143|rigid:IDlrQJoGydTypSzPj8mX6Azug1k	false	-	sufficient binding region:82-400	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38781	uniprotkb:Q9Y6N9-4	intact:EBI-24549|uniprotkb:D3DL05|ensemblfungi:YHR056C	intact:EBI-11523636|ensembl:ENSP00000436934	psi-mi:rsc30_yeast(display_long)|uniprotkb:RSC30(gene name)|psi-mi:RSC30(display_short)|uniprotkb:Remodel the structure of chromatin complex subunit 30(gene name synonym)|uniprotkb:YHR056C(locus name)	psi-mi:q9y6n9-4(display_long)|uniprotkb:USH1C(gene name)|psi-mi:USH1C(display_short)|uniprotkb:AIE75(gene name synonym)|uniprotkb:Antigen NY-CO-38/NY-CO-37(gene name synonym)|uniprotkb:Autoimmune enteropathy-related antigen AIE-75(gene name synonym)|uniprotkb:Protein PDZ-73(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-3(gene name synonym)|uniprotkb:Usher syndrome type-1C protein(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11529490|imex:IM-24995-747	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011923.2|sgd:S000001098|dip:DIP-4275N|ensemblfungi:YHR056C(gene)|ensemblfungi:YHR056C_mRNA(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006337"(nucleosome disassembly)|rcsb pdb:6KW4|rcsb pdb:6KW5|rcsb pdb:6V8O|rcsb pdb:6V92|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016586"(RSC-type complex)|interpro:IPR001138(Fungal transcriptional regulatory protein, N-terminal)|interpro:IPR036864|rcsb pdb:6K15|rcsb pdb:6KW3|sgd:YHR056C(identity)	ensembl:ENSG00000006611(gene)|ensembl:ENST00000527020(transcript)|intact:EBI-954308(isoform-parent)|uniprotkb:Q9Y6N9-4(isoform-parent)|entrezgene/locuslink:10083(identity)	-	-	isoform-comment:No experimental confirmation available.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:NzGOxIaNyDat2EcQdWPobugunh0559292	rogid:lC4fbXfsFOZFtutcdQYHSWpgcJY9606	intact-crc:5D68076349F7B4F0|rigid:NGbrqKUhac/AX2xIvvMSab9r7RA	false	sufficient binding region:52-883	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96KN7-4	uniprotkb:P38781	intact:EBI-11525164|ensembl:ENSP00000372391	intact:EBI-24549|uniprotkb:D3DL05|ensemblfungi:YHR056C	psi-mi:q96kn7-4(display_long)|uniprotkb:RPGRIP1(gene name)|psi-mi:RPGRIP1(display_short)	psi-mi:rsc30_yeast(display_long)|uniprotkb:RSC30(gene name)|psi-mi:RSC30(display_short)|uniprotkb:Remodel the structure of chromatin complex subunit 30(gene name synonym)|uniprotkb:YHR056C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11529479|imex:IM-24995-746	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-1050213(isoform-parent)|ensembl:ENSG00000092200(gene)|ensembl:ENST00000382933(transcript)|uniprotkb:Q96KN7-4(isoform-parent)|entrezgene/locuslink:57096(identity)	refseq:NP_011923.2|sgd:S000001098|dip:DIP-4275N|ensemblfungi:YHR056C(gene)|ensemblfungi:YHR056C_mRNA(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006337"(nucleosome disassembly)|rcsb pdb:6KW4|rcsb pdb:6KW5|rcsb pdb:6V8O|rcsb pdb:6V92|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016586"(RSC-type complex)|interpro:IPR001138(Fungal transcriptional regulatory protein, N-terminal)|interpro:IPR036864|rcsb pdb:6K15|rcsb pdb:6KW3|sgd:YHR056C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Xy0433uM/nWhWLM/EsfESPJDIy49606	rogid:NzGOxIaNyDat2EcQdWPobugunh0559292	intact-crc:A04078395B173FBA|rigid:+lhorYUPJWwM4GE9f+q87nqe1Iw	false	-	sufficient binding region:52-883	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96GY0	uniprotkb:P38822	intact:EBI-5458880|uniprotkb:Q9Y372|ensembl:ENSP00000263849	intact:EBI-3889|uniprotkb:E9P8V2|uniprotkb:D3DL64|ensemblfungi:YHR114W	psi-mi:zc21a_human(display_long)|uniprotkb:ZC2HC1A(gene name)|psi-mi:ZC2HC1A(display_short)|uniprotkb:C8orf70(gene name synonym)|uniprotkb:FAM164A(gene name synonym)|uniprotkb:CGI-62(orf name)	psi-mi:bzz1_yeast(display_long)|uniprotkb:BZZ1(gene name)|psi-mi:BZZ1(display_short)|uniprotkb:LAS17-binding protein 7(gene name synonym)|uniprotkb:LSB7(gene name synonym)|uniprotkb:YHR114W(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11529566|imex:IM-24995-755	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_057094.2|ensembl:ENSG00000104427(gene)|ensembl:ENST00000263849(transcript)|go:"GO:0046872"(metal ion binding)|interpro:IPR026319|entrezgene/locuslink:51101(identity)	refseq:NP_011982.1|sgd:S000001156|dip:DIP-2143N|mint:P38822|ensemblfungi:YHR114W(gene)|ensemblfungi:YHR114W_mRNA(transcript)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006897"(endocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0009651"(response to salt stress)|go:"GO:0030479"(actin cortical patch)|go:"GO:0043332"(mating projection tip)|go:"GO:0045010"(actin nucleation)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR027267|interpro:IPR031160|interpro:IPR036028|rcsb pdb:1ZUU|rcsb pdb:2A28|reactome:R-SCE-8856828|reactome:R-SCE-9013406|reactome:R-SCE-9696270|sgd:YHR114W(identity)	-	-	crc64:5C73DACC69611B41	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:5QYEwHhPJBrdqbU1jKnxdZFYC7c9606	rogid:lnoTdZ+pWCE2mDz3Ha7VQOOCfM8559292	intact-crc:E1E9EDCCE25A2C5C|rigid:c7PMZXUdiAE6cIMTeiRiWPtID/c	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38815	uniprotkb:Q9UI14	intact:EBI-24665|uniprotkb:D3DL55|ensemblfungi:YHR105W	intact:EBI-712367|ensembl:ENSP00000222008|uniprotkb:Q7Z4Y2|uniprotkb:Q9Y3R1	psi-mi:ypt35_yeast(display_long)|uniprotkb:YHR105W(locus name)|uniprotkb:YPT35(gene name)|psi-mi:YPT35(display_short)	psi-mi:praf1_human(display_long)|uniprotkb:PRA1 family protein 1(gene name synonym)|uniprotkb:RABAC1(gene name)|psi-mi:RABAC1(display_short)|uniprotkb:PRA1(gene name synonym)|uniprotkb:PRAF1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11529557|imex:IM-24995-754	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011973.1|sgd:S000001147|dip:DIP-1881N|ensemblfungi:YHR105W(gene)|ensemblfungi:YHR105W_mRNA(transcript)|go:"GO:0005768"(endosome)|go:"GO:0010008"(endosome membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|interpro:IPR001683(Phox-like)|interpro:IPR036871|interpro:IPR037917|sgd:YHR105W(identity)	refseq:NP_006414.2|ensembl:ENSG00000105404(gene)|ensembl:ENST00000222008(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0070064"(proline-rich region binding)|interpro:IPR004895(Prenylated rab acceptor PRA1)|mint:Q9UI14|entrezgene/locuslink:10567(identity)	-	crc64:2ADD21AF107094DC	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:fUTJG8BaTveH3zB/0W1vNh4BU2Y559292	rogid:WS2rUY7yXRbR7pqWgfUCbnEiDbg9606	intact-crc:314F10391DFE6FB8|rigid:prvpKhWrJiDUl4kjr1YUwrA7ZTc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38815	uniprotkb:Q96HR9	intact:EBI-24665|uniprotkb:D3DL55|ensemblfungi:YHR105W	intact:EBI-750345|uniprotkb:Q96LM0|uniprotkb:B2RE01|uniprotkb:A0A1L5BXV3|uniprotkb:D6W5Z0|ensembl:ENSP00000378861	psi-mi:ypt35_yeast(display_long)|uniprotkb:YHR105W(locus name)|uniprotkb:YPT35(gene name)|psi-mi:YPT35(display_short)	psi-mi:reep6_human(display_long)|uniprotkb:Polyposis locus protein 1-like 1(gene name synonym)|uniprotkb:REEP6(gene name)|psi-mi:REEP6(display_short)|uniprotkb:C19orf32(gene name synonym)|uniprotkb:DP1L1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11529548|imex:IM-24995-753	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011973.1|sgd:S000001147|dip:DIP-1881N|ensemblfungi:YHR105W(gene)|ensemblfungi:YHR105W_mRNA(transcript)|go:"GO:0005768"(endosome)|go:"GO:0010008"(endosome membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|interpro:IPR001683(Phox-like)|interpro:IPR036871|interpro:IPR037917|sgd:YHR105W(identity)	refseq:NP_612402.1|refseq:NP_001316485.1|ensembl:ENSG00000115255(gene)|ensembl:ENST00000395479(transcript)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030665"(clathrin-coated vesicle membrane)|go:"GO:0032386"(regulation of intracellular transport)|go:"GO:0050908"(detection of light stimulus involved in visual perception)|interpro:IPR004345(TB2/DP1 and HVA22 related protein)|mint:Q96HR9|reactome:R-HSA-381753|go:"GO:0005634"(nucleus)|entrezgene/locuslink:92840(identity)	-	crc64:2ADD21AF107094DC	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2017/05/05	rogid:fUTJG8BaTveH3zB/0W1vNh4BU2Y559292	rogid:pB8AjjNTpmaaLJ8j7MCBM45UAHE9606	intact-crc:9A80189EE06162A9|rigid:c9CbZDzhbB3Kso14dHqlrn66Jag	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38815	uniprotkb:Q8WW34-2	intact:EBI-24665|uniprotkb:D3DL55|ensemblfungi:YHR105W	intact:EBI-11528917|ensembl:ENSP00000369959	psi-mi:ypt35_yeast(display_long)|uniprotkb:YHR105W(locus name)|uniprotkb:YPT35(gene name)|psi-mi:YPT35(display_short)	psi-mi:q8ww34-2(display_long)|uniprotkb:TMEM239(gene name)|psi-mi:TMEM239(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11529539|imex:IM-24995-752	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011973.1|sgd:S000001147|dip:DIP-1881N|ensemblfungi:YHR105W(gene)|ensemblfungi:YHR105W_mRNA(transcript)|go:"GO:0005768"(endosome)|go:"GO:0010008"(endosome membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|interpro:IPR001683(Phox-like)|interpro:IPR036871|interpro:IPR037917|sgd:YHR105W(identity)	intact:EBI-9675724(isoform-parent)|uniprotkb:Q8WW34-2(isoform-parent)|ensembl:ENSG00000198326(gene)|ensembl:ENST00000380585(transcript)|entrezgene/locuslink:100288797(identity)	-	crc64:2ADD21AF107094DC	isoform-comment:No experimental confirmation available.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:fUTJG8BaTveH3zB/0W1vNh4BU2Y559292	rogid:1VqWIwPpWs6WjW8eDoJUHz2pegw9606	intact-crc:5B70078128BC9629|rigid:Tc5Z00Ijf1H/4/CoUQ9k/8XVdxs	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38815	uniprotkb:Q6RW13-2	intact:EBI-24665|uniprotkb:D3DL55|ensemblfungi:YHR105W	intact:EBI-11522760|ensembl:ENSP00000365816	psi-mi:ypt35_yeast(display_long)|uniprotkb:YHR105W(locus name)|uniprotkb:YPT35(gene name)|psi-mi:YPT35(display_short)	psi-mi:q6rw13-2(display_long)|uniprotkb:AGTRAP(gene name)|psi-mi:AGTRAP(display_short)|uniprotkb:AT1 receptor-associated protein(gene name synonym)|uniprotkb:ATRAP(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11529530|imex:IM-24995-751	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011973.1|sgd:S000001147|dip:DIP-1881N|ensemblfungi:YHR105W(gene)|ensemblfungi:YHR105W_mRNA(transcript)|go:"GO:0005768"(endosome)|go:"GO:0010008"(endosome membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|interpro:IPR001683(Phox-like)|interpro:IPR036871|interpro:IPR037917|sgd:YHR105W(identity)	ensembl:ENSG00000177674(gene)|ensembl:ENST00000376629(transcript)|intact:EBI-741181(isoform-parent)|uniprotkb:Q6RW13-2(isoform-parent)|entrezgene/locuslink:57085(identity)	-	crc64:2ADD21AF107094DC	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:fUTJG8BaTveH3zB/0W1vNh4BU2Y559292	rogid:PNzVis/8puQZBJ562gCqZKc078s9606	intact-crc:79E1D7BA7BC0463B|rigid:TljLFTagZAaBJcwIVz4e6tNIXTU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q13137	uniprotkb:P38815	intact:EBI-739580|uniprotkb:B4DDC4|uniprotkb:E7ENK0|uniprotkb:Q53FQ5|uniprotkb:Q53HB5|uniprotkb:Q6IBN9|uniprotkb:Q9BTF7|uniprotkb:B2RBT0|ensembl:ENSP00000258947|uniprotkb:B4E0C0|uniprotkb:E7ETP5|uniprotkb:B4DDT4|uniprotkb:B4DP36|uniprotkb:E9PBE5	intact:EBI-24665|uniprotkb:D3DL55|ensemblfungi:YHR105W	psi-mi:caco2_human(display_long)|uniprotkb:CALCOCO2(gene name)|psi-mi:CALCOCO2(display_short)|uniprotkb:NDP52(gene name synonym)|uniprotkb:Nuclear domain 10 protein NDP52(gene name synonym)|uniprotkb:Antigen nuclear dot 52 kDa protein(gene name synonym)|uniprotkb:Nuclear dot protein 52(gene name synonym)	psi-mi:ypt35_yeast(display_long)|uniprotkb:YHR105W(locus name)|uniprotkb:YPT35(gene name)|psi-mi:YPT35(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11529521|imex:IM-24995-750	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001248319.1|refseq:NP_001248320.1|refseq:NP_001248322.1|refseq:NP_005822.1|ensembl:ENSG00000136436(gene)|ensembl:ENST00000258947(transcript)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016032"(viral process)|go:"GO:0016605"(PML body)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0098792"(xenophagy)|go:"GO:1901098"(positive regulation of autophagosome maturation)|interpro:IPR041611|interpro:IPR041641|mint:Q13137|rcsb pdb:2MXP|rcsb pdb:3VVV|rcsb pdb:3VVW|rcsb pdb:4GXL|rcsb pdb:4HAN|rcsb pdb:4XKL|rcsb pdb:5AAQ|rcsb pdb:5Z7A|rcsb pdb:5Z7L|refseq:NP_001248324.1|dip:DIP-57534N|entrezgene/locuslink:10241(identity)	refseq:NP_011973.1|sgd:S000001147|dip:DIP-1881N|ensemblfungi:YHR105W(gene)|ensemblfungi:YHR105W_mRNA(transcript)|go:"GO:0005768"(endosome)|go:"GO:0010008"(endosome membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|interpro:IPR001683(Phox-like)|interpro:IPR036871|interpro:IPR037917|sgd:YHR105W(identity)	-	crc64:609B121DA1A9DCB8	crc64:2ADD21AF107094DC	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:N/GPJUGBK+Dh5Cg+csmafphuo9M9606	rogid:fUTJG8BaTveH3zB/0W1vNh4BU2Y559292	intact-crc:CA5A60DC8FB17455|rigid:uCIg90GaLpsIGsMeB/4WqatfkPQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96BA8	uniprotkb:P38842	intact:EBI-6942903|ensembl:ENSP00000481956|intact:MINT-268046|intact:MINT-8162577|uniprotkb:Q8N2D5|uniprotkb:Q96CP0	intact:EBI-24752|uniprotkb:D3DL89|uniprotkb:Q6B2K3|ensemblfungi:YHR140W	psi-mi:cr3l1_human(display_long)|uniprotkb:CREB3L1(gene name)|psi-mi:CREB3L1(display_short)|uniprotkb:OASIS(gene name synonym)|uniprotkb:PSEC0238(orf name)|uniprotkb:Old astrocyte specifically-induced substance(gene name synonym)	psi-mi:yhu0_yeast(display_long)|uniprotkb:YHR140W(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11529611|imex:IM-24995-760	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157613(gene)|ensembl:ENST00000621158(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0070278"(extracellular matrix constituent secretion)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029805|mint:Q96BA8|reactome:R-HSA-8874211|refseq:NP_443086.1|entrezgene/locuslink:90993(identity)	refseq:NP_012009.1|sgd:S000001182|dip:DIP-1786N|ensemblfungi:YHR140W(gene)|ensemblfungi:YHR140W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR006838(FAR-17a/AIG1-like protein)|sgd:YHR140W(identity)	-	comment:mint|function:"Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE"	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:sMWUFmBeBBCO+T0Y2CuB/un1lBg9606	rogid:3CroWy45MlZdD8WyMGvawdwQhrs559292	intact-crc:9F627021CFA20982|rigid:0DA9kqjAyPL7wELZ/7YsnW6pIKk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8N6L0	uniprotkb:P38842	intact:EBI-749265|uniprotkb:Q96MC3|ensembl:ENSP00000404220	intact:EBI-24752|uniprotkb:D3DL89|uniprotkb:Q6B2K3|ensemblfungi:YHR140W	psi-mi:kash5_human(display_long)|uniprotkb:KASH5(gene name)|psi-mi:KASH5(display_short)|uniprotkb:CCDC155(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 155(gene name synonym)|uniprotkb:KASH domain-containing protein 5(gene name synonym)	psi-mi:yhu0_yeast(display_long)|uniprotkb:YHR140W(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11529602|imex:IM-24995-759	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_653289.3|ensembl:ENSG00000161609(gene)|ensembl:ENST00000447857(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034397"(telomere localization)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051225"(spindle assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0090172"(microtubule cytoskeleton organization involved in homologous chromosome segregation)|go:"GO:0090220"(chromosome localization to nuclear envelope involved in homologous chromosome segregation)|go:"GO:0090619"(meiotic spindle pole)|interpro:IPR011992(EF-Hand type)|interpro:IPR028168|interpro:IPR028170|interpro:IPR039508|mint:Q8N6L0|rcsb pdb:6R2I|rcsb pdb:6WMF|entrezgene/locuslink:147872(identity)	refseq:NP_012009.1|sgd:S000001182|dip:DIP-1786N|ensemblfungi:YHR140W(gene)|ensemblfungi:YHR140W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR006838(FAR-17a/AIG1-like protein)|sgd:YHR140W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Wl9L7AcvDHCZuKjYLn8QgGIbZTc9606	rogid:3CroWy45MlZdD8WyMGvawdwQhrs559292	intact-crc:FA3ECB64F0BE7563|rigid:pFlcWSa+b6rZZSlavQm3DHY7grw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38838	uniprotkb:P63279	intact:EBI-24737|uniprotkb:D3DL83|ensemblfungi:YHR134W	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	psi-mi:wss1_yeast(display_long)|uniprotkb:YHR134W(locus name)|uniprotkb:WSS1(gene name)|psi-mi:WSS1(display_short)|uniprotkb:Weak suppressor of SMT3 protein 1(gene name synonym)|uniprotkb:DNA damage response protein WSS1(gene name synonym)|uniprotkb:SUMO-dependent isopeptidase WSS1(gene name synonym)	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11529593|imex:IM-24995-758	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012002.1|sgd:S000001176|dip:DIP-1600N|ensemblfungi:YHR134W(gene)|ensemblfungi:YHR134W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0006508"(proteolysis)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0010224"(response to UV-B)|go:"GO:0010225"(response to UV-C)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019985"(translesion synthesis)|go:"GO:0032183"(SUMO binding)|go:"GO:0036205"(histone catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0061665"(SUMO ligase activity)|go:"GO:0106300"(protein-DNA covalent cross-linking repair)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|go:"GO:1990466"(protein autosumoylation)|interpro:IPR013536(WLM)|sgd:YHR134W(identity)	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N|entrezgene/locuslink:7329(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:nRxYgrZjnBdPN8uneoPl3Rq01+g559292	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	intact-crc:BC86E8B3B9D88742|rigid:mRIfEHJp/M50+xqUmA9KVh7Eb1c	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8N6L0	uniprotkb:P38837	intact:EBI-749265|uniprotkb:Q96MC3|ensembl:ENSP00000404220	intact:EBI-24733|uniprotkb:D3DL82|uniprotkb:Q6Q5G1|ensemblfungi:YHR133C	psi-mi:kash5_human(display_long)|uniprotkb:KASH5(gene name)|psi-mi:KASH5(display_short)|uniprotkb:CCDC155(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 155(gene name synonym)|uniprotkb:KASH domain-containing protein 5(gene name synonym)	psi-mi:nsg1_yeast(display_long)|uniprotkb:INSIG homolog 1(gene name synonym)|uniprotkb:YHR133C(locus name)|uniprotkb:NSG1(gene name)|psi-mi:NSG1(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11529584|imex:IM-24995-757	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_653289.3|ensembl:ENSG00000161609(gene)|ensembl:ENST00000447857(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034397"(telomere localization)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051225"(spindle assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0090172"(microtubule cytoskeleton organization involved in homologous chromosome segregation)|go:"GO:0090220"(chromosome localization to nuclear envelope involved in homologous chromosome segregation)|go:"GO:0090619"(meiotic spindle pole)|interpro:IPR011992(EF-Hand type)|interpro:IPR028168|interpro:IPR028170|interpro:IPR039508|mint:Q8N6L0|rcsb pdb:6R2I|rcsb pdb:6WMF|entrezgene/locuslink:147872(identity)	sgd:S000001175|refseq:NP_012001.1|dip:DIP-2775N|mint:P38837|ensemblfungi:YHR133C(gene)|ensemblfungi:YHR133C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016126"(sterol biosynthetic process)|go:"GO:0034399"(nuclear periphery)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR025929|sgd:YHR133C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Wl9L7AcvDHCZuKjYLn8QgGIbZTc9606	rogid:ALle5Ub0gjK3Uh+6sfIgbfa7BYw559292	intact-crc:7715F7CF428D7766|rigid:GGHvrnEzAxYlA3jNZxR9DvvfxHw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38828	uniprotkb:Q8TAP6	intact:EBI-24700|uniprotkb:D3DL71|ensemblfungi:YHR121W	intact:EBI-742887|ensembl:ENSP00000262127|uniprotkb:Q658N5|uniprotkb:Q9H9U7|uniprotkb:B0YJB2|uniprotkb:B4DXG5|uniprotkb:B4DZW1	psi-mi:lsm12_yeast(display_long)|uniprotkb:YHR121W(locus name)|uniprotkb:LSM12(gene name)|psi-mi:LSM12(display_short)|uniprotkb:Sm-like protein 12(gene name synonym)	psi-mi:cep76_human(display_long)|uniprotkb:CEP76(gene name)|psi-mi:CEP76(display_short)|uniprotkb:C18orf9(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11529575|imex:IM-24995-756	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011989.1|sgd:S000001163|dip:DIP-5545N|mint:P38828|ensemblfungi:YHR121W(gene)|ensemblfungi:YHR121W_mRNA(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016070"(RNA metabolic process)|interpro:IPR016521(Uncharacterised conserved protein UCP007783, YHR121w)|interpro:IPR019181|interpro:IPR039683|sgd:YHR121W(identity)	refseq:NP_079175.2|ensembl:ENSG00000101624(gene)|ensembl:ENST00000262127(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0046599"(regulation of centriole replication)|interpro:IPR028926|interpro:IPR038765|mint:Q8TAP6|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_001258918.1|entrezgene/locuslink:79959(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:6xw9WGjtFwkmKlO6QHoSSS2aMro559292	rogid:fWzb8oIU35oVWomyDrf8u5sbxUk9606	intact-crc:6010D566AB32D492|rigid:4MdpdXBICplRwkaqS7/1NVvtVeQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UMX0	uniprotkb:P38868	intact:EBI-741480|uniprotkb:Q8IXS9|uniprotkb:Q8N2Q3|uniprotkb:Q9H0T8|uniprotkb:Q9H3R4|uniprotkb:Q9HAZ5|intact:EBI-28967608|ensembl:ENSP00000365576|uniprotkb:Q5T6J5|uniprotkb:Q5T6J9|uniprotkb:A0A024R284	intact:EBI-24840|uniprotkb:A0A1S0T004|ensemblfungi:YHR180W	psi-mi:ubql1_human(display_long)|uniprotkb:Protein linking IAP with cytoskeleton 1(gene name synonym)|uniprotkb:UBQLN1(gene name)|psi-mi:UBQLN1(display_short)|uniprotkb:DA41(gene name synonym)|uniprotkb:PLIC1(gene name synonym)	psi-mi:yhy0_yeast(display_long)|uniprotkb:YHR180W(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11529650|imex:IM-24995-764	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000257468|ensembl:ENSP00000257468|ensembl:ENSP00000365576|ensembl:ENSG00000135018(gene)|ensembl:ENST00000376395(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000502"(proteasome complex)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016235"(aggresome)|go:"GO:0016236"(macroautophagy)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0019900"(kinase binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035973"(aggrephagy)|go:"GO:0042802"(identical protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0097352"(autophagosome maturation)|go:"GO:1901340"(negative regulation of store-operated calcium channel activity)|go:"GO:1902175"(regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)|interpro:IPR000626(Ubiquitin)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR028430|interpro:IPR029071|mint:Q9UMX0|rcsb pdb:2JY5|rcsb pdb:2JY6|rcsb pdb:2KLC|reactome:R-HSA-8856825|refseq:NP_038466.2|refseq:NP_444295.1|dip:DIP-41629N|entrezgene/locuslink:29979(identity)	sgd:S000001223|dip:DIP-4332N|ensemblfungi:YHR180W(gene)|ensemblfungi:YHR180W_mRNA(transcript)|go:"GO:0016021"(integral component of membrane)|sgd:YHR180W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:nCFfZbGCTvRYaXhQ4R99XblslvM9606	rogid:E7zJN1iVyb08WvBGa7NXcqw4sqw559292	intact-crc:585050F530504225|rigid:q50hN7Nm+coUXkalINXCfafkEsE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q6P1W5	uniprotkb:P38868	intact:EBI-946029|uniprotkb:B3KVT1|uniprotkb:Q96IC8|ensembl:ENSP00000435634|uniprotkb:D3DPR3|uniprotkb:E9PJ76	intact:EBI-24840|uniprotkb:A0A1S0T004|ensemblfungi:YHR180W	psi-mi:ca094_human(display_long)|uniprotkb:C1orf94(gene name)|psi-mi:C1orf94(display_short)	psi-mi:yhy0_yeast(display_long)|uniprotkb:YHR180W(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11529639|imex:IM-24995-763	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001128206.1|refseq:NP_116273.2|ensembl:ENSG00000142698(gene)|ensembl:ENST00000488417(transcript)|interpro:IPR031496|entrezgene/locuslink:84970(identity)	sgd:S000001223|dip:DIP-4332N|ensemblfungi:YHR180W(gene)|ensemblfungi:YHR180W_mRNA(transcript)|go:"GO:0016021"(integral component of membrane)|sgd:YHR180W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:y1o4xWvTl2CBA1J7jsP7y8ZjLzM9606	rogid:E7zJN1iVyb08WvBGa7NXcqw4sqw559292	intact-crc:16C25B8DC4373D29|rigid:hVpdiBz4Xv9ToxTQ5x2xu/Sj0QU	false	sufficient binding region:191-598	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q13049	uniprotkb:P38868	intact:EBI-742790|ensembl:ENSP00000363095|ensembl:ENSP00000408292|uniprotkb:Q9NQP8	intact:EBI-24840|uniprotkb:A0A1S0T004|ensemblfungi:YHR180W	psi-mi:tri32_human(display_long)|uniprotkb:Zinc finger protein HT2A(gene name synonym)|uniprotkb:72 kDa Tat-interacting protein(gene name synonym)|uniprotkb:TRIM32(gene name)|psi-mi:TRIM32(display_short)|uniprotkb:HT2A(gene name synonym)|uniprotkb:Tripartite motif-containing protein 32(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM32(gene name synonym)	psi-mi:yhy0_yeast(display_long)|uniprotkb:YHR180W(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11529630|imex:IM-24995-762	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0043621"(protein self-association)|go:"GO:0045087"(innate immune response)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051155"(positive regulation of striated muscle cell differentiation)|go:"GO:0061564"(axon development)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1902187"|go:"GO:1902230"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:1903265"(positive regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:1903883"(positive regulation of interleukin-17-mediated signaling pathway)|go:"GO:1903886"("positive regulation of chemokine (C-C motif) ligand 20 production")|go:"GO:2000147"(positive regulation of cell motility)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENSG00000119401(gene)|ensembl:ENST00000373983(transcript)|ensembl:ENST00000450136(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001894"(tissue homeostasis)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005863"(striated muscle myosin thick filament)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007014"(actin ubiquitination)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009411"(response to UV)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0017022"(myosin binding)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030957"(Tat protein binding)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034612"(response to tumor necrosis factor)|go:"GO:0042802"(identical protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|interpro:IPR000315(Zinc finger, B-box)|refseq:NP_001093149.1|refseq:XP_011516700.1|refseq:NP_036342.2|refseq:XP_005251870.1|interpro:IPR001258(NHL repeat)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR013017(NHL repeat, subgroup)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR027370|mint:Q13049|rcsb pdb:2CT2|rcsb pdb:5FEY|reactome:R-HSA-3134975|reactome:R-HSA-983168|refseq:XP_016869975.1|entrezgene/locuslink:22954(identity)	sgd:S000001223|dip:DIP-4332N|ensemblfungi:YHR180W(gene)|ensemblfungi:YHR180W_mRNA(transcript)|go:"GO:0016021"(integral component of membrane)|sgd:YHR180W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:XuqprQd10kSpsuyGs+FSdzIdJ/Y9606	rogid:E7zJN1iVyb08WvBGa7NXcqw4sqw559292	intact-crc:7C78B4DC48A401F9|rigid:AjIWCkstYp9m6gL/ZjCq5bWK7gc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O43765	uniprotkb:P38868	intact:EBI-347996|ensembl:ENSP00000221566|ensembl:ENSP00000503397|ensembl:ENSP00000504495|uniprotkb:Q9BTZ9|intact:EBI-1045243|uniprotkb:Q6FIA9|uniprotkb:D6W610	intact:EBI-24840|uniprotkb:A0A1S0T004|ensemblfungi:YHR180W	psi-mi:sgta_human(display_long)|uniprotkb:SGTA(gene name)|psi-mi:SGTA(display_short)|uniprotkb:SGT(gene name synonym)|uniprotkb:Alpha-SGT(gene name synonym)|uniprotkb:Vpu-binding protein(gene name synonym)|uniprotkb:SGT1(gene name synonym)	psi-mi:yhy0_yeast(display_long)|uniprotkb:YHR180W(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11529621|imex:IM-24995-761	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:4CPG|rcsb pdb:4GOD|rcsb pdb:4GOE|rcsb pdb:4GOF|reactome:R-HSA-9609523|rcsb pdb:2VYI|ensembl:ENSG00000104969(gene)|ensembl:ENST00000221566(transcript)|ensembl:ENST00000676943(transcript)|ensembl:ENST00000677149(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072380"(TRC complex)|go:"GO:0098850"(extrinsic component of synaptic vesicle membrane)|go:"GO:1903070"(negative regulation of ER-associated ubiquitin-dependent protein catabolic process)|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)|go:"GO:1903646"(positive regulation of chaperone-mediated protein folding)|go:"GO:1904288"(BAT3 complex binding)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR032374|mint:O43765|refseq:XP_011526480.1|refseq:NP_003012.1|entrezgene/locuslink:6449(identity)	sgd:S000001223|dip:DIP-4332N|ensemblfungi:YHR180W(gene)|ensemblfungi:YHR180W_mRNA(transcript)|go:"GO:0016021"(integral component of membrane)|sgd:YHR180W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:r/Cyj4UJk/cS8QdrbjhTZMPCigI9606	rogid:E7zJN1iVyb08WvBGa7NXcqw4sqw559292	intact-crc:3733771B5D91F2D5|rigid:xhGW+dGqWWFn41O+2W907wqnGZk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38886	uniprotkb:Q9BYV6-2	intact:EBI-15949|ensemblfungi:YHR200W|uniprotkb:D3DLE9	intact:EBI-11522718|ensembl:ENSP00000297348	psi-mi:rpn10_yeast(display_long)|uniprotkb:RPN10(gene name)|psi-mi:RPN10(display_short)|uniprotkb:MCB1(gene name synonym)|uniprotkb:SUN1(gene name synonym)|uniprotkb:YHR200W(locus name)	psi-mi:q9byv6-2(display_long)|uniprotkb:TRIM55(gene name)|psi-mi:TRIM55(display_short)|uniprotkb:MURF2(gene name synonym)|uniprotkb:Muscle-specific RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 29(gene name synonym)|uniprotkb:RNF29(gene name synonym)|uniprotkb:p50(isoform synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11529689|imex:IM-24995-768	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YHR200W(gene)|ensemblfungi:YHR200W_mRNA(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|sgd:S000001243|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0036435"(K48-linked polyubiquitin modification-dependent protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043248"(proteasome assembly)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR027040|interpro:IPR036465|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5LN1|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5MPD|rcsb pdb:5MPE|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|refseq:NP_012070.3|dip:DIP-2100N|mint:P38886|sgd:YHR200W(identity)	intact:EBI-2341179(isoform-parent)|uniprotkb:Q9BYV6-2(isoform-parent)|ensembl:ENSG00000147573(gene)|ensembl:ENST00000353317(transcript)|entrezgene/locuslink:84675(identity)	-	crc64:8A05198B0CD7C0C3	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Lg2bjPWMUcvXdLDZZMWFWyXbCcA559292	rogid:9t8UhK+Z1yBqjnQrOqPD76NuXGg9606	intact-crc:D84530FF625468B1|rigid:YoDMoSc/LsIPVqeFajJU5v39FdY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9HCM9-2	uniprotkb:P38879	intact:EBI-11523450|ensembl:ENSP00000365847|ensembl:ENSP00000373095|ensembl:ENSP00000373097|ensembl:ENSP00000379797|ensembl:ENSP00000379800|ensembl:ENSP00000383486|ensembl:ENSP00000387445|ensembl:ENSP00000389198|ensembl:ENSP00000389852|ensembl:ENSP00000392130|ensembl:ENSP00000394353|ensembl:ENSP00000396986|ensembl:ENSP00000398956|ensembl:ENSP00000401071|ensembl:ENSP00000401184|ensembl:ENSP00000404340|ensembl:ENSP00000404904|ensembl:ENSP00000411582|ensembl:ENSP00000412743|ensembl:ENSP00000414525|ensembl:ENSP00000415259	intact:EBI-6379|uniprotkb:D3DLE1|ensemblfungi:YHR193C	psi-mi:q9hcm9-2(display_long)|uniprotkb:TRIM39(gene name)|psi-mi:TRIM39(display_short)|uniprotkb:RING finger protein 23(gene name synonym)|uniprotkb:RNF23(gene name synonym)|uniprotkb:TFP(gene name synonym)|uniprotkb:Testis-abundant finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 39(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM39(gene name synonym)|uniprotkb:TIM39beta(isoform synonym)	psi-mi:naca_yeast(display_long)|uniprotkb:EGD2(gene name)|psi-mi:EGD2(display_short)|uniprotkb:Alpha-NAC(gene name synonym)|uniprotkb:GAL4 DNA-binding enhancer protein 2(gene name synonym)|uniprotkb:YHR193C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11529679|imex:IM-24995-767	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-739510(isoform-parent)|ensembl:ENSG00000204599(gene)|ensembl:ENSG00000206495(gene)|ensembl:ENSG00000224994(gene)|ensembl:ENSG00000226437(gene)|ensembl:ENSG00000229929(gene)|ensembl:ENSG00000230308(gene)|ensembl:ENSG00000232839(gene)|ensembl:ENST00000376659(transcript)|ensembl:ENST00000383601(transcript)|ensembl:ENST00000383603(transcript)|ensembl:ENST00000396548(transcript)|ensembl:ENST00000396551(transcript)|ensembl:ENST00000400644(transcript)|ensembl:ENST00000414015(transcript)|ensembl:ENST00000419790(transcript)|ensembl:ENST00000430502(transcript)|ensembl:ENST00000431272(transcript)|ensembl:ENST00000433900(transcript)|ensembl:ENST00000438076(transcript)|ensembl:ENST00000438859(transcript)|ensembl:ENST00000440117(transcript)|ensembl:ENST00000443109(transcript)|ensembl:ENST00000446397(transcript)|ensembl:ENST00000449318(transcript)|ensembl:ENST00000450778(transcript)|ensembl:ENST00000451132(transcript)|ensembl:ENST00000452705(transcript)|ensembl:ENST00000458607(transcript)|uniprotkb:Q9HCM9-2(isoform-parent)|entrezgene/locuslink:56658(identity)	sgd:S000001236|refseq:NP_012063.3|mint:P38879|dip:DIP-2098N|ensemblfungi:YHR193C(gene)|ensemblfungi:YHR193C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005854"(nascent polypeptide-associated complex)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0070300"(phosphatidic acid binding)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|interpro:IPR002715(Nascent polypeptide-associated complex NAC)|interpro:IPR009060(UBA-like)|interpro:IPR016641(Nascent polypeptide-associated complex, alpha subunit)|interpro:IPR038187|interpro:IPR044034|sgd:YHR193C(identity)	-	-	crc64:86CE0C4E6194C286	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:UfSn2+IVRxtGomVeDGdZpL7mz5I9606	rogid:IjsgR+hZDgTQDvy2Wf8JEX4kF+A559292	intact-crc:F82F8702C0F3C15E|rigid:A0MHhunKyob6sVK1SSl8etIg/pU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38879	uniprotkb:P20290-2	intact:EBI-6379|uniprotkb:D3DLE1|ensemblfungi:YHR193C	intact:EBI-1054703|ensembl:ENSP00000338516	psi-mi:naca_yeast(display_long)|uniprotkb:EGD2(gene name)|psi-mi:EGD2(display_short)|uniprotkb:Alpha-NAC(gene name synonym)|uniprotkb:GAL4 DNA-binding enhancer protein 2(gene name synonym)|uniprotkb:YHR193C(locus name)	psi-mi:p20290-2(display_long)|uniprotkb:BTF3b(isoform synonym)|uniprotkb:BTF3(gene name)|psi-mi:BTF3(display_short)|uniprotkb:NACB(gene name synonym)|uniprotkb:RNA polymerase B transcription factor 3(gene name synonym)|uniprotkb:OK/SW-cl.8(orf name)|uniprotkb:Nascent polypeptide-associated complex subunit beta(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11529670|imex:IM-24995-766	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000001236|refseq:NP_012063.3|mint:P38879|dip:DIP-2098N|ensemblfungi:YHR193C(gene)|ensemblfungi:YHR193C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005854"(nascent polypeptide-associated complex)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0070300"(phosphatidic acid binding)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|interpro:IPR002715(Nascent polypeptide-associated complex NAC)|interpro:IPR009060(UBA-like)|interpro:IPR016641(Nascent polypeptide-associated complex, alpha subunit)|interpro:IPR038187|interpro:IPR044034|sgd:YHR193C(identity)	intact:EBI-1054687(btf3_human)|ensembl:ENSG00000145741(gene)|ensembl:ENST00000335895(transcript)|uniprotkb:P20290-2(isoform-parent)|entrezgene/locuslink:689(identity)	-	crc64:86CE0C4E6194C286	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:IjsgR+hZDgTQDvy2Wf8JEX4kF+A559292	rogid:nViZ1CRkho2stQQ1ts0kUzwhOO09606	intact-crc:43A92DA3AD88F2DF|rigid:YbdnKjy0+72+LWtuT2IYSXhsw1o	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:G5E962	uniprotkb:P38871	intact:EBI-11525615|ensembl:ENSP00000328177	intact:EBI-24852|uniprotkb:D3DLD2|ensemblfungi:YHR184W	psi-mi:g5e962_human(display_long)|uniprotkb:hCG_1644200(orf name)|uniprotkb:MAGEA11(gene name)|psi-mi:MAGEA11(display_short)	psi-mi:ssp1_yeast(display_long)|uniprotkb:SSP1(gene name)|psi-mi:SSP1(display_short)|uniprotkb:YHR184W(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11529659|imex:IM-24995-765	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001011544.1|ensembl:ENSG00000185247(gene)|ensembl:ENST00000333104(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016604"(nuclear body)|interpro:IPR002190(MAGE protein)|interpro:IPR021072|interpro:IPR030099|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|entrezgene/locuslink:4110(identity)	sgd:S000001227|refseq:NP_012054.1|dip:DIP-1674N|ensemblfungi:YHR184W(gene)|ensemblfungi:YHR184W_mRNA(transcript)|go:"GO:0005628"(prospore membrane)|go:"GO:0030476"(ascospore wall assembly)|go:"GO:0032120"(ascospore-type prospore membrane formation)|go:"GO:0051301"(cell division)|go:"GO:0070056"(prospore membrane leading edge)|sgd:YHR184W(identity)	-	-	crc64:A199EB4159771A03	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:sVB0aA6yibWUx/d2SE+pwpKKgtI9606	rogid:oYmvoKYf2OWiVyfG4zRm731HTRs559292	intact-crc:B58A507B0D41506E|rigid:V13Cy51tf7GR/hmN/udbtu+VqSk	false	sufficient binding region:82-400	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UMX0	uniprotkb:P38886	intact:EBI-741480|uniprotkb:Q8IXS9|uniprotkb:Q8N2Q3|uniprotkb:Q9H0T8|uniprotkb:Q9H3R4|uniprotkb:Q9HAZ5|intact:EBI-28967608|ensembl:ENSP00000365576|uniprotkb:Q5T6J5|uniprotkb:Q5T6J9|uniprotkb:A0A024R284	intact:EBI-15949|ensemblfungi:YHR200W|uniprotkb:D3DLE9	psi-mi:ubql1_human(display_long)|uniprotkb:Protein linking IAP with cytoskeleton 1(gene name synonym)|uniprotkb:UBQLN1(gene name)|psi-mi:UBQLN1(display_short)|uniprotkb:DA41(gene name synonym)|uniprotkb:PLIC1(gene name synonym)	psi-mi:rpn10_yeast(display_long)|uniprotkb:RPN10(gene name)|psi-mi:RPN10(display_short)|uniprotkb:MCB1(gene name synonym)|uniprotkb:SUN1(gene name synonym)|uniprotkb:YHR200W(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11529698|imex:IM-24995-769	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000257468|ensembl:ENSP00000257468|ensembl:ENSP00000365576|ensembl:ENSG00000135018(gene)|ensembl:ENST00000376395(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000502"(proteasome complex)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016235"(aggresome)|go:"GO:0016236"(macroautophagy)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0019900"(kinase binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035973"(aggrephagy)|go:"GO:0042802"(identical protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0097352"(autophagosome maturation)|go:"GO:1901340"(negative regulation of store-operated calcium channel activity)|go:"GO:1902175"(regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)|interpro:IPR000626(Ubiquitin)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR028430|interpro:IPR029071|mint:Q9UMX0|rcsb pdb:2JY5|rcsb pdb:2JY6|rcsb pdb:2KLC|reactome:R-HSA-8856825|refseq:NP_038466.2|refseq:NP_444295.1|dip:DIP-41629N|entrezgene/locuslink:29979(identity)	ensemblfungi:YHR200W(gene)|ensemblfungi:YHR200W_mRNA(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|sgd:S000001243|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0036435"(K48-linked polyubiquitin modification-dependent protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043248"(proteasome assembly)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR027040|interpro:IPR036465|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5LN1|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5MPD|rcsb pdb:5MPE|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|refseq:NP_012070.3|dip:DIP-2100N|mint:P38886|sgd:YHR200W(identity)	-	-	crc64:8A05198B0CD7C0C3	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:nCFfZbGCTvRYaXhQ4R99XblslvM9606	rogid:Lg2bjPWMUcvXdLDZZMWFWyXbCcA559292	intact-crc:589FBCFBC0FBB07A|rigid:jRQ6SH8wVZdoEyLJO0cGcrIO2eI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96HU1	uniprotkb:P38913	intact:EBI-7362971|uniprotkb:B0QY79|intact:UNK-5498582|uniprotkb:Q7Z709|uniprotkb:Q9NT69|ensembl:ENSP00000248929	intact:EBI-6763|ensemblfungi:YDL045C|uniprotkb:D6VRV1	psi-mi:sgsm3_human(display_long)|uniprotkb:SGSM3(gene name)|psi-mi:SGSM3(display_short)|uniprotkb:MAP(gene name synonym)|uniprotkb:RABGAPLP(gene name synonym)|uniprotkb:RUTBC3(gene name synonym)|uniprotkb:RUN and TBC1 domain-containing protein 3(gene name synonym)|uniprotkb:Rab-GTPase-activating protein-like protein(gene name synonym)|uniprotkb:Merlin-associated protein(gene name synonym)	psi-mi:fad1_yeast(display_long)|uniprotkb:FAD1(gene name)|psi-mi:FAD1(display_short)|uniprotkb:FMN adenylyltransferase(gene name synonym)|uniprotkb:D2702(orf name)|uniprotkb:YDL045C(locus name)|uniprotkb:FAD pyrophosphorylase(gene name synonym)|uniprotkb:Flavin adenine dinucleotide synthase(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11529726|imex:IM-24995-772	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001288778.1|refseq:NP_056520.2|ensembl:ENSG00000100359(gene)|ensembl:ENST00000248929(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005829"(cytosol)|go:"GO:0005921"(gap junction)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007049"(cell cycle)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032483"(regulation of Rab protein signal transduction)|go:"GO:0032486"(Rap protein signal transduction)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0048227"(plasma membrane to endosome transport)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR001452(Src homology-3)|interpro:IPR004012(RUN)|interpro:IPR035833|interpro:IPR035969|interpro:IPR036028|interpro:IPR037213|entrezgene/locuslink:27352(identity)	refseq:NP_010239.1|sgd:S000002203|ensemblfungi:YDL045C(gene)|ensemblfungi:YDL045C_mRNA(transcript)|go:"GO:0003919"(FMN adenylyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006747"(FAD biosynthetic process)|interpro:IPR002500(Phosphoadenosine phosphosulphate reductase)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|rcsb pdb:2WSI|reactome:R-SCE-196843|dip:DIP-4735N|sgd:YDL045C(identity)	-	function:May play a cooperative role in NF2-mediated growth suppression of cells|comment:mint|comment:homomint	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:9V+BpqGXordWG7hcdP/l6QL4+Lg9606	rogid:fdv5ldkxx7ZxwNTBS+oAAbwPkOc559292	intact-crc:7779C06149978D66|rigid:MBbbXEOtPz5tgr0lhq0U/cqNHgA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96BA8	uniprotkb:P38894	intact:EBI-6942903|ensembl:ENSP00000481956|intact:MINT-268046|intact:MINT-8162577|uniprotkb:Q8N2D5|uniprotkb:Q96CP0	intact:EBI-6990|uniprotkb:D3DLG0|ensemblfungi:YHR211W	psi-mi:cr3l1_human(display_long)|uniprotkb:CREB3L1(gene name)|psi-mi:CREB3L1(display_short)|uniprotkb:OASIS(gene name synonym)|uniprotkb:PSEC0238(orf name)|uniprotkb:Old astrocyte specifically-induced substance(gene name synonym)	psi-mi:flo5_yeast(display_long)|uniprotkb:YHR211W(locus name)|uniprotkb:FLO5(gene name)|psi-mi:FLO5(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11529716|imex:IM-24995-771	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157613(gene)|ensembl:ENST00000621158(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0070278"(extracellular matrix constituent secretion)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029805|mint:Q96BA8|reactome:R-HSA-8874211|refseq:NP_443086.1|entrezgene/locuslink:90993(identity)	refseq:NP_012081.1|sgd:S000001254|dip:DIP-4056N|ensemblfungi:YHR211W(gene)|ensemblfungi:YHR211W_mRNA(transcript)|go:"GO:0000128"(flocculation)|go:"GO:0005537"(mannose binding)|go:"GO:0005576"(extracellular region)|go:"GO:0009277"(fungal-type cell wall)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0031589"(cell-substrate adhesion)|go:"GO:0071944"(cell periphery)|interpro:IPR001389(Flocculin)|interpro:IPR011658(PA14)|interpro:IPR025928|interpro:IPR037524|rcsb pdb:2XJP|rcsb pdb:2XJQ|rcsb pdb:2XJR|rcsb pdb:2XJS|rcsb pdb:2XJT|rcsb pdb:2XJU|rcsb pdb:2XJV|rcsb pdb:4AHW|rcsb pdb:4AHX|rcsb pdb:4AHY|rcsb pdb:4AHZ|rcsb pdb:4AI0|rcsb pdb:4AI1|rcsb pdb:4AI2|rcsb pdb:4AI3|sgd:YHR211W(identity)	-	comment:mint|function:"Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE"	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:sMWUFmBeBBCO+T0Y2CuB/un1lBg9606	rogid:kWs25Mzne+np7M/ebYwa4Fg1yqg559292	intact-crc:01E1B19A8750A41C|rigid:6ICkyyI0yZYCyTwytnUg3TaeUrA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O14641	uniprotkb:P38891	intact:EBI-740850|ensembl:ENSP00000005340|uniprotkb:Q53XM0|uniprotkb:D3DTN3	intact:EBI-3455|uniprotkb:D3DLF7|ensemblfungi:YHR208W	psi-mi:dvl2_human(display_long)|uniprotkb:DSH homolog 2(gene name synonym)|uniprotkb:DVL2(gene name)|psi-mi:DVL2(display_short)	psi-mi:bca1_yeast(display_long)|uniprotkb:Protein TWT1(gene name synonym)|uniprotkb:Protein ECA39(gene name synonym)|uniprotkb:BAT1(gene name)|psi-mi:BAT1(display_short)|uniprotkb:ECA39(gene name synonym)|uniprotkb:TWT1(gene name synonym)|uniprotkb:YHR208W(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11529707|imex:IM-24995-770	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004413.1|ensembl:ENSG00000004975(gene)|ensembl:ENST00000005340(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005109"(frizzled binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0007507"(heart development)|go:"GO:0016235"(aggresome)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044340"(canonical Wnt signaling pathway involved in regulation of cell proliferation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0150012"(positive regulation of neuron projection arborization)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008341(Dishevelled-2 region)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:O14641|rcsb pdb:2REY|rcsb pdb:3CBX|rcsb pdb:3CBY|rcsb pdb:3CBZ|rcsb pdb:3CC0|rcsb pdb:4WIP|rcsb pdb:5LNP|rcsb pdb:5SUY|rcsb pdb:5SUZ|rcsb pdb:6IW3|rcsb pdb:6JCK|reactome:R-HSA-201681|reactome:R-HSA-201688|reactome:R-HSA-2028269|reactome:R-HSA-4086400|reactome:R-HSA-4608870|reactome:R-HSA-4641258|reactome:R-HSA-4641262|reactome:R-HSA-5099900|reactome:R-HSA-5368598|reactome:R-HSA-5663220|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9673324|ensembl:ENSP00000005340|dip:DIP-34433N|entrezgene/locuslink:1856(identity)	sgd:S000001251|reactome:R-SCE-70895|refseq:NP_012078.3|dip:DIP-6475N|ensemblfungi:YHR208W(gene)|ensemblfungi:YHR208W_mRNA(transcript)|go:"GO:0004084"(branched-chain-amino-acid transaminase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0009082"(branched-chain amino acid biosynthetic process)|go:"GO:0009083"(branched-chain amino acid catabolic process)|go:"GO:0009097"(isoleucine biosynthetic process)|go:"GO:0009098"(leucine biosynthetic process)|go:"GO:0009099"(valine biosynthetic process)|go:"GO:0019509"(L-methionine salvage from methylthioadenosine)|go:"GO:0050048"("L-leucine:2-oxoglutarate aminotransferase activity")|go:"GO:0052654"(L-leucine transaminase activity)|go:"GO:0052655"(L-valine transaminase activity)|go:"GO:0052656"(L-isoleucine transaminase activity)|interpro:IPR001544(Aminotransferase, class IV)|interpro:IPR005786(Branched-chain amino acid aminotransferase II)|interpro:IPR018300|interpro:IPR033939|interpro:IPR036038|interpro:IPR043131|interpro:IPR043132|sgd:YHR208W(identity)	-	-	crc64:E76604F326A7C674	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:2Vdc8oRnT4Mz/j+EXQXrL3AszOc9606	rogid:Rz/okB+egLztOJhwPzzPpl8yXlc559292	intact-crc:0472DCA93821FA2C|rigid:afXbXqSons1qGvi/zoOlKg8qE0s	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P63279	uniprotkb:P38986	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	intact:EBI-3014|uniprotkb:D6VSV3|ensemblfungi:YDR321W	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:aspg1_yeast(display_long)|uniprotkb:YDR321W(locus name)|uniprotkb:D9798.6(orf name)|uniprotkb:ASP1(gene name)|psi-mi:ASP1(display_short)|uniprotkb:L-asparaginase I(gene name synonym)|uniprotkb:L-asparagine amidohydrolase I(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11529746|imex:IM-24995-774	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N|entrezgene/locuslink:7329(identity)	sgd:S000002729|refseq:NP_010607.3|dip:DIP-4030N|mint:P38986|ensemblfungi:YDR321W(gene)|ensemblfungi:YDR321W_mRNA(transcript)|go:"GO:0004067"(asparaginase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006530"(asparagine catabolic process)|go:"GO:0042597"(periplasmic space)|interpro:IPR004550(L-asparaginase, type II)|interpro:IPR006034(Asparaginase/glutaminase)|interpro:IPR020827|interpro:IPR027473|interpro:IPR027474|interpro:IPR027475|interpro:IPR036152|interpro:IPR037152|interpro:IPR040919|sgd:YDR321W(identity)	-	-	crc64:8204CB7C58B5B75F	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	rogid:vIy3riBmCKfYQjsh3cIcO7o1Bzw559292	intact-crc:188DDFB063A1EFE6|rigid:5tyG65EjXp2hDPPyg7E12KfBvvE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38986	uniprotkb:Q96IK5	intact:EBI-3014|uniprotkb:D6VSV3|ensemblfungi:YDR321W	intact:EBI-2548508|ensembl:ENSP00000282570|uniprotkb:Q9H826|uniprotkb:Q9H8V7|uniprotkb:Q9H927	psi-mi:aspg1_yeast(display_long)|uniprotkb:YDR321W(locus name)|uniprotkb:D9798.6(orf name)|uniprotkb:ASP1(gene name)|psi-mi:ASP1(display_short)|uniprotkb:L-asparaginase I(gene name synonym)|uniprotkb:L-asparagine amidohydrolase I(gene name synonym)	psi-mi:gmcl1_human(display_long)|uniprotkb:GMCL1(gene name)|psi-mi:GMCL1(display_short)|uniprotkb:GCL(gene name synonym)|uniprotkb:BTBD13(gene name synonym)|uniprotkb:SPATA29(gene name synonym)|uniprotkb:Spermatogenesis-associated protein 29(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11529755|imex:IM-24995-775	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002729|refseq:NP_010607.3|dip:DIP-4030N|mint:P38986|ensemblfungi:YDR321W(gene)|ensemblfungi:YDR321W_mRNA(transcript)|go:"GO:0004067"(asparaginase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006530"(asparagine catabolic process)|go:"GO:0042597"(periplasmic space)|interpro:IPR004550(L-asparaginase, type II)|interpro:IPR006034(Asparaginase/glutaminase)|interpro:IPR020827|interpro:IPR027473|interpro:IPR027474|interpro:IPR027475|interpro:IPR036152|interpro:IPR037152|interpro:IPR040919|sgd:YDR321W(identity)	ensembl:ENSG00000087338(gene)|ensembl:ENST00000282570(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0007281"(germ cell development)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016363"(nuclear matrix)|go:"GO:0042802"(identical protein binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR043380|refseq:NP_848526.1|entrezgene/locuslink:64395(identity)	-	crc64:8204CB7C58B5B75F	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:vIy3riBmCKfYQjsh3cIcO7o1Bzw559292	rogid:ED8yqySVu7BWxpw3DUSNBZSQWrk9606	intact-crc:2E1E2CAF43D7C164|rigid:oy943M8+iFCiGMpW9GCtR8GGXvI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38932	uniprotkb:Q13190	intact:EBI-20444|uniprotkb:D6VU50|ensemblfungi:YGL095C	intact:EBI-714206|uniprotkb:Q5U0D4|uniprotkb:Q7Z3T6|uniprotkb:Q9BUG1|uniprotkb:B2R8T2|ensembl:ENSP00000294179|uniprotkb:F8W8Q9	psi-mi:vps45_yeast(display_long)|uniprotkb:VPS45(gene name)|psi-mi:VPS45(display_short)|uniprotkb:STT10(gene name synonym)|uniprotkb:VPL28(gene name synonym)|uniprotkb:YGL095C(locus name)	psi-mi:stx5_human(display_long)|uniprotkb:STX5(gene name)|psi-mi:STX5(display_short)|uniprotkb:STX5A(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11529735|imex:IM-24995-773	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003063|refseq:NP_011420.3|ensemblfungi:YGL095C(gene)|ensemblfungi:YGL095C_mRNA(transcript)|go:"GO:0000011"(vacuole inheritance)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0007033"(vacuole organization)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0035543"(positive regulation of SNARE complex assembly)|go:"GO:0048210"(Golgi vesicle fusion to target membrane)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR001619(Sec1-like protein)|interpro:IPR027482|interpro:IPR036045|interpro:IPR043127|interpro:IPR043154|reactome:R-SCE-983231|dip:DIP-2693N|mint:P38932|sgd:YGL095C(identity)	refseq:NP_003155.2|ensembl:ENSG00000162236(gene)|ensembl:ENST00000294179(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006906"(vesicle fusion)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0031982"(vesicle)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034498"(early endosome to Golgi transport)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0045296"(cadherin binding)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048278"(vesicle docking)|go:"GO:0048280"(vesicle fusion with Golgi apparatus)|go:"GO:0090166"(Golgi disassembly)|go:"GO:1903358"(regulation of Golgi organization)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|interpro:IPR021538|mint:Q13190|rcsb pdb:3EFO|reactome:R-HSA-204005|reactome:R-HSA-5694530|reactome:R-HSA-6807878|reactome:R-HSA-6811438|reactome:R-HSA-8980692|reactome:R-HSA-9013106|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|reactome:R-HSA-9013408|reactome:R-HSA-9609523|refseq:NP_001231595.1|refseq:NP_001317223.1|dip:DIP-56987N|entrezgene/locuslink:6811(identity)	-	crc64:4AA50D568228228F	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:HSNdSBz2AD5AS/nSUjPV02ym8HQ559292	rogid:cR4cS695ZWQQ5Bkim9HqmCE0hCE9606	intact-crc:3D94F767182582EC|rigid:fn3RpZMtWU2aSdpMHGtsEOjS0pI	false	-	sufficient binding region:55-355	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O00444	uniprotkb:P39009	intact:EBI-746202|uniprotkb:Q8IYF0|uniprotkb:Q96Q95|uniprotkb:B2RAL0|uniprotkb:B7Z837|uniprotkb:B7Z8G7|uniprotkb:Q9UD84|uniprotkb:Q9UDE2|ensembl:ENSP00000270861	intact:EBI-6194|uniprotkb:D6VRP9|ensemblfungi:YDL101C	psi-mi:plk4_human(display_long)|uniprotkb:Polo-like kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase Sak(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 18(gene name synonym)|uniprotkb:PLK4(gene name)|psi-mi:PLK4(display_short)|uniprotkb:SAK(gene name synonym)|uniprotkb:STK18(gene name synonym)	psi-mi:dun1_yeast(display_long)|uniprotkb:DUN1(gene name)|psi-mi:DUN1(display_short)|uniprotkb:D2370(orf name)|uniprotkb:YDL101C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11529773|imex:IM-24995-777	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001177728.1|refseq:NP_001177730.1|refseq:NP_055079.3|dip:DIP-34467N|rcsb pdb:5LHZ|rcsb pdb:6N45|rcsb pdb:6N46|rcsb pdb:6W38|rcsb pdb:6W3I|rcsb pdb:6W3J|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|rcsb pdb:5LHY|reactome:R-HSA-5620912|reactome:R-HSA-8854518|ensembl:ENSG00000142731(gene)|ensembl:ENST00000270861(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0001741"(XY body)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007099"(centriole replication)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0046601"(positive regulation of centriole replication)|go:"GO:0060271"(cilium assembly)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0098535"(de novo centriole assembly involved in multi-ciliated epithelial cell differentiation)|go:"GO:0098536"(deuterosome)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033696|interpro:IPR033698|interpro:IPR033699|interpro:IPR033700|mint:O00444|rcsb pdb:2N19|rcsb pdb:3COK|rcsb pdb:4JXF|rcsb pdb:4N7V|rcsb pdb:4N7Z|rcsb pdb:4N9J|rcsb pdb:4YUR|rcsb pdb:4YYP|entrezgene/locuslink:10733(identity)	refseq:NP_010182.1|sgd:S000002259|dip:DIP-1772N|reactome:R-SCE-5693565|reactome:R-SCE-69473|reactome:R-SCE-69601|reactome:R-SCE-75035|ensemblfungi:YDL101C(gene)|ensemblfungi:YDL101C_mRNA(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0042770"(signal transduction in response to DNA damage)|go:"GO:0044773"(mitotic DNA damage checkpoint signaling)|go:"GO:0048478"(replication fork protection)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000253(Forkhead-associated)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:2JQJ|rcsb pdb:2JQL|sgd:YDL101C(identity)	-	-	crc64:4990F24F024702D7	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:xqjVEnoGXDk/+2AzLRAkyPK80OI9606	rogid:/BmlSDRdkj7efDRuXH/qWpdTv/U559292	intact-crc:7D6F4D467E7A8532|rigid:3TXIx6nf/xaNuijN+DIwGHgtYHI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O14641	uniprotkb:P39009	intact:EBI-740850|ensembl:ENSP00000005340|uniprotkb:Q53XM0|uniprotkb:D3DTN3	intact:EBI-6194|uniprotkb:D6VRP9|ensemblfungi:YDL101C	psi-mi:dvl2_human(display_long)|uniprotkb:DSH homolog 2(gene name synonym)|uniprotkb:DVL2(gene name)|psi-mi:DVL2(display_short)	psi-mi:dun1_yeast(display_long)|uniprotkb:DUN1(gene name)|psi-mi:DUN1(display_short)|uniprotkb:D2370(orf name)|uniprotkb:YDL101C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11529782|imex:IM-24995-778	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004413.1|ensembl:ENSG00000004975(gene)|ensembl:ENST00000005340(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005109"(frizzled binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0007507"(heart development)|go:"GO:0016235"(aggresome)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044340"(canonical Wnt signaling pathway involved in regulation of cell proliferation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0150012"(positive regulation of neuron projection arborization)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008341(Dishevelled-2 region)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:O14641|rcsb pdb:2REY|rcsb pdb:3CBX|rcsb pdb:3CBY|rcsb pdb:3CBZ|rcsb pdb:3CC0|rcsb pdb:4WIP|rcsb pdb:5LNP|rcsb pdb:5SUY|rcsb pdb:5SUZ|rcsb pdb:6IW3|rcsb pdb:6JCK|reactome:R-HSA-201681|reactome:R-HSA-201688|reactome:R-HSA-2028269|reactome:R-HSA-4086400|reactome:R-HSA-4608870|reactome:R-HSA-4641258|reactome:R-HSA-4641262|reactome:R-HSA-5099900|reactome:R-HSA-5368598|reactome:R-HSA-5663220|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9673324|ensembl:ENSP00000005340|dip:DIP-34433N|entrezgene/locuslink:1856(identity)	refseq:NP_010182.1|sgd:S000002259|dip:DIP-1772N|reactome:R-SCE-5693565|reactome:R-SCE-69473|reactome:R-SCE-69601|reactome:R-SCE-75035|ensemblfungi:YDL101C(gene)|ensemblfungi:YDL101C_mRNA(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0042770"(signal transduction in response to DNA damage)|go:"GO:0044773"(mitotic DNA damage checkpoint signaling)|go:"GO:0048478"(replication fork protection)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000253(Forkhead-associated)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:2JQJ|rcsb pdb:2JQL|sgd:YDL101C(identity)	-	-	crc64:4990F24F024702D7	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:2Vdc8oRnT4Mz/j+EXQXrL3AszOc9606	rogid:/BmlSDRdkj7efDRuXH/qWpdTv/U559292	intact-crc:2816E8572BE51CC2|rigid:8ujev4UxGU6V0MpRNV9N7YEpg+E	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O94972	uniprotkb:P39009	intact:EBI-741602|uniprotkb:Q7Z3E6|uniprotkb:Q8IYF7|uniprotkb:Q8WYF7|intact:EBI-28976055|ensembl:ENSP00000262294|ensembl:ENSP00000376785|uniprotkb:A8K0V9|uniprotkb:A8K8U4|uniprotkb:A8MZ79|uniprotkb:B4DGZ3|uniprotkb:F8WEE6	intact:EBI-6194|uniprotkb:D6VRP9|ensemblfungi:YDL101C	psi-mi:tri37_human(display_long)|uniprotkb:Mulibrey nanism protein(gene name synonym)|uniprotkb:TRIM37(gene name)|psi-mi:TRIM37(display_short)|uniprotkb:KIAA0898(gene name synonym)|uniprotkb:MUL(gene name synonym)|uniprotkb:POB1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 37(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM37(gene name synonym)	psi-mi:dun1_yeast(display_long)|uniprotkb:DUN1(gene name)|psi-mi:DUN1(display_short)|uniprotkb:D2370(orf name)|uniprotkb:YDL101C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11529791|imex:IM-24995-779	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001005207.1|refseq:NP_056109.1|refseq:NP_001307916.1|ensembl:ENSP00000262294|ensembl:ENST00000393065|ensembl:ENSP00000376784|ensembl:ENSP00000376785|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046600"(negative regulation of centriole replication)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070842"(aggresome assembly)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002083(MATH)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR008974(TRAF-like)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR037299|rcsb pdb:3LRQ|reactome:R-HSA-983168|ensembl:ENSG00000108395(gene)|ensembl:ENST00000262294(transcript)|ensembl:ENST00000393066(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005777"(peroxisome)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016235"(aggresome)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0035518"(histone H2A monoubiquitination)|refseq:NP_001307919.1|dip:DIP-34437N|entrezgene/locuslink:4591(identity)	refseq:NP_010182.1|sgd:S000002259|dip:DIP-1772N|reactome:R-SCE-5693565|reactome:R-SCE-69473|reactome:R-SCE-69601|reactome:R-SCE-75035|ensemblfungi:YDL101C(gene)|ensemblfungi:YDL101C_mRNA(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0042770"(signal transduction in response to DNA damage)|go:"GO:0044773"(mitotic DNA damage checkpoint signaling)|go:"GO:0048478"(replication fork protection)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000253(Forkhead-associated)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:2JQJ|rcsb pdb:2JQL|sgd:YDL101C(identity)	-	-	crc64:4990F24F024702D7	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:y2njeO0MUBrKU9MUvkbo1uZmqkE9606	rogid:/BmlSDRdkj7efDRuXH/qWpdTv/U559292	intact-crc:234952EAEAF903D7|rigid:QR+AyAVHr6gXRTVaED8l3Arm+Xg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38991	uniprotkb:P63279	intact:EBI-9319|ensemblfungi:YPL209C|uniprotkb:D6W3G1	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	psi-mi:ipl1_yeast(display_long)|uniprotkb:IPL1(gene name)|psi-mi:IPL1(display_short)|uniprotkb:YPL209C(locus name)|uniprotkb:Aurora kinase(gene name synonym)|uniprotkb:Increase-in-ploidy protein 1(gene name synonym)	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11529764|imex:IM-24995-776	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YPL209C(gene)|ensemblfungi:YPL209C_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005828"(kinetochore microtubule)|go:"GO:0005874"(microtubule)|go:"GO:0005876"(spindle microtubule)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008608"(attachment of spindle microtubules to kinetochore)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0032133"(chromosome passenger complex)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0035174"(histone serine kinase activity)|go:"GO:0044774"(mitotic DNA integrity checkpoint signaling)|go:"GO:0045143"(homologous chromosome segregation)|go:"GO:0045144"(meiotic sister chromatid segregation)|go:"GO:0051228"(mitotic spindle disassembly)|go:"GO:0051233"(spindle midzone)|go:"GO:0090266"(regulation of mitotic cell cycle spindle assembly checkpoint)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901673"(regulation of mitotic spindle assembly)|go:"GO:1901925"(negative regulation of protein import into nucleus during spindle assembly checkpoint)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR030616|reactome:R-SCE-8854050|refseq:NP_015115.1|sgd:S000006130|dip:DIP-2771N|mint:P38991|sgd:YPL209C(identity)	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N|entrezgene/locuslink:7329(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:hNg/pnDWxuP6BSpguV7aFh50wtE559292	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	intact-crc:6C068F106841C1C2|rigid:6iS+zoUtLDyAWkBXjVkV2AjXdmg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O14777	uniprotkb:P39518	intact:EBI-715849|uniprotkb:Q6PJX2|ensembl:ENSP00000261597	intact:EBI-10082|uniprotkb:D3DLR3|ensemblfungi:YER015W	psi-mi:ndc80_human(display_long)|uniprotkb:Kinetochore protein Hec1(gene name synonym)|uniprotkb:Kinetochore-associated protein 2(gene name synonym)|uniprotkb:Highly expressed in cancer protein(gene name synonym)|uniprotkb:Retinoblastoma-associated protein HEC(gene name synonym)|uniprotkb:NDC80(gene name)|psi-mi:NDC80(display_short)|uniprotkb:HEC(gene name synonym)|uniprotkb:KNTC2(gene name synonym)|uniprotkb:HEC1(gene name synonym)	psi-mi:lcf2_yeast(display_long)|uniprotkb:YER015W(locus name)|uniprotkb:FAA2(gene name)|psi-mi:FAA2(display_short)|uniprotkb:FAM1(gene name synonym)|uniprotkb:Long-chain acyl-CoA synthetase 2(gene name synonym)|uniprotkb:Fatty acid activator 2(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11529828|imex:IM-24995-783	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006092.1|ensembl:ENSG00000080986(gene)|ensembl:ENST00000261597(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000940"(outer kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008608"(attachment of spindle microtubules to kinetochore)|go:"GO:0016020"(membrane)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051298"(centrosome duplication)|go:"GO:0051301"(cell division)|go:"GO:0051310"(metaphase plate congression)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051383"(kinetochore organization)|go:"GO:0090267"(positive regulation of mitotic cell cycle spindle assembly checkpoint)|go:"GO:1905342"(positive regulation of protein localization to kinetochore)|interpro:IPR005550(HEC/Ndc80p)|interpro:IPR038273|interpro:IPR040967|mint:O14777|rcsb pdb:2IGP|rcsb pdb:2VE7|rcsb pdb:3IZ0|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|dip:DIP-35100N|entrezgene/locuslink:10403(identity)	sgd:S000000817|ensemblfungi:YER015W_mRNA(transcript)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0004467"(long-chain fatty acid-CoA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0015910"(long-chain fatty acid import into peroxisome)|go:"GO:0015916"(fatty-acyl-CoA transport)|go:"GO:0016020"(membrane)|go:"GO:0031956"(medium-chain fatty acid-CoA ligase activity)|go:"GO:0031957"(very long-chain fatty acid-CoA ligase activity)|go:"GO:0042760"(very long-chain fatty acid catabolic process)|go:"GO:0102391"(decanoate-CoA ligase activity)|ensemblfungi:YER015W(gene)|interpro:IPR020845|interpro:IPR000873(AMP-dependent synthetase and ligase)|reactome:R-SCE-75876|refseq:NP_010931.3|dip:DIP-6565N|sgd:YER015W(identity)	-	-	crc64:1E023C18682805BC	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:5OsXbZPvJTMWPepp7M+AXlJUQ649606	rogid:N0W+wPvCsl01y0k8hJZ156LztOo559292	intact-crc:E0517378865AE6D2|rigid:1gnk8ybQrgiQ3DaBb+Wo4SQgyjc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P39518	uniprotkb:O00635	intact:EBI-10082|uniprotkb:D3DLR3|ensemblfungi:YER015W	intact:EBI-2130415|uniprotkb:B2R862|ensembl:ENSP00000349596	psi-mi:lcf2_yeast(display_long)|uniprotkb:YER015W(locus name)|uniprotkb:FAA2(gene name)|psi-mi:FAA2(display_short)|uniprotkb:FAM1(gene name synonym)|uniprotkb:Long-chain acyl-CoA synthetase 2(gene name synonym)|uniprotkb:Fatty acid activator 2(gene name synonym)	psi-mi:tri38_human(display_long)|uniprotkb:TRIM38(gene name)|psi-mi:TRIM38(display_short)|uniprotkb:RNF15(gene name synonym)|uniprotkb:RORET(gene name synonym)|uniprotkb:RING finger protein 15(gene name synonym)|uniprotkb:Zinc finger protein RoRet(gene name synonym)|uniprotkb:Tripartite motif-containing protein 38(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM38(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11529819|imex:IM-24995-782	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000000817|ensemblfungi:YER015W_mRNA(transcript)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0004467"(long-chain fatty acid-CoA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0015910"(long-chain fatty acid import into peroxisome)|go:"GO:0015916"(fatty-acyl-CoA transport)|go:"GO:0016020"(membrane)|go:"GO:0031956"(medium-chain fatty acid-CoA ligase activity)|go:"GO:0031957"(very long-chain fatty acid-CoA ligase activity)|go:"GO:0042760"(very long-chain fatty acid catabolic process)|go:"GO:0102391"(decanoate-CoA ligase activity)|ensemblfungi:YER015W(gene)|interpro:IPR020845|interpro:IPR000873(AMP-dependent synthetase and ligase)|reactome:R-SCE-75876|refseq:NP_010931.3|dip:DIP-6565N|sgd:YER015W(identity)	refseq:NP_006346.1|refseq:XP_005248856.1|refseq:XP_005248857.1|ensembl:ENSG00000112343(gene)|ensembl:ENST00000357085(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046598"(positive regulation of viral entry into host cell)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR035790|interpro:IPR043136|reactome:R-HSA-877300|entrezgene/locuslink:10475(identity)	-	crc64:1E023C18682805BC	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:N0W+wPvCsl01y0k8hJZ156LztOo559292	rogid:Zh4X/6v/qKZlDkMV6hhn7OsvPnQ9606	intact-crc:C449743A0AB946BC|rigid:DYAXS5I8rCUG/nH272qtRBbq/p8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P39014	uniprotkb:A0A0C4DGF1	intact:EBI-11507|uniprotkb:D6VVN6|ensemblfungi:YIL046W	intact:EBI-10188476|ensembl:ENSP00000433657	psi-mi:met30_yeast(display_long)|uniprotkb:YIL046W(locus name)|uniprotkb:MET30(gene name)|psi-mi:MET30(display_short)|uniprotkb:Methionine-requiring protein 30(gene name synonym)|uniprotkb:"E3 ubiquitin ligase complex SCF(Met30) subunit MET30"(gene name synonym)	psi-mi:a0a0c4dgf1_human(display_long)|uniprotkb:ZBTB32(gene name)|psi-mi:ZBTB32(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11529800|imex:IM-24995-780	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YIL046W_mRNA(transcript)|ensemblfungi:YIL046W(gene)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009086"(methionine biosynthetic process)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019344"(cysteine biosynthetic process)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043224"(nuclear SCF ubiquitin ligase complex)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0046686"(response to cadmium ion)|interpro:IPR001680(WD40 repeat)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036047|interpro:IPR036322|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|refseq:NP_012218.1|sgd:S000001308|mint:P39014|dip:DIP-1439N|sgd:YIL046W(identity)	interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|ensembl:ENSG00000011590(gene)|ensembl:ENST00000481182(transcript)|go:"GO:0042802"(identical protein binding)|entrezgene/locuslink:27033(identity)	-	crc64:5135D4BCA2E1EB97	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:B138OcWsG8zW/eFMselD2pFyy5c559292	rogid:w3k7YT4kw/T+Xi5YBqGHSpHtwMM9606	intact-crc:C63699C0C458007F|rigid:IXhuelB6Pd5JIjAYg+O/Vx1v0tM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P39078	uniprotkb:Q13287	intact:EBI-19054|uniprotkb:Q07561|uniprotkb:D6VRK5|ensemblfungi:YDL143W	intact:EBI-372942|uniprotkb:Q53TI8|intact:EBI-10174268|uniprotkb:Q8WTW2|uniprotkb:Q9BVE5|uniprotkb:B5BU69|ensembl:ENSP00000243346	psi-mi:tcpd_yeast(display_long)|uniprotkb:YDL143W(locus name)|uniprotkb:CCT4(gene name)|psi-mi:CCT4(display_short)|uniprotkb:ANC2(gene name synonym)|uniprotkb:TCP4(gene name synonym)|uniprotkb:CCT-delta(gene name synonym)	psi-mi:nmi_human(display_long)|uniprotkb:NMI(gene name)|psi-mi:NMI(display_short)|uniprotkb:N-myc and STAT interactor(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11529809|imex:IM-24995-781	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010138.1|sgd:S000002302|ensemblfungi:YDL143W(gene)|ensemblfungi:YDL143W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0006457"(protein folding)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012717(T-complex protein 1, delta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|rcsb pdb:4V81|rcsb pdb:4V8R|rcsb pdb:4V94|rcsb pdb:5GW4|rcsb pdb:5GW5|rcsb pdb:6KRD|rcsb pdb:6KRE|rcsb pdb:6KS6|rcsb pdb:6KS7|rcsb pdb:6KS8|reactome:R-SCE-390471|reactome:R-SCE-6814122|dip:DIP-6753N|mint:P39078|sgd:YDL143W(identity)	refseq:NP_004679.2|refseq:XP_005246998.1|ensembl:ENSG00000123609(gene)|ensembl:ENST00000243346(transcript)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0032687"(negative regulation of interferon-alpha production)|go:"GO:0032688"(negative regulation of interferon-beta production)|go:"GO:0034142"(toll-like receptor 4 signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0045824"(negative regulation of innate immune response)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:1901223"(negative regulation of NIK/NF-kappaB signaling)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1902524"(positive regulation of protein K48-linked ubiquitination)|interpro:IPR009909(Nmi/IFP 35)|interpro:IPR009938(Interferon-induced 35 kDa, N-terminal)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033527|mint:Q13287|refseq:XP_016860736.1|entrezgene/locuslink:9111(identity)	-	crc64:F01146D76F4E850C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:GCSpoIEgtQxu/8dbncxp/4AXEls559292	rogid:qOkzIuloaWW88apb9JH2DT/Bnuk9606	intact-crc:80F66C7D69F0973C|rigid:iQuVQOjFrxdRxUi15OftIUlJaN0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O95197-3	uniprotkb:P39518	intact:EBI-11525735|ensembl:ENSP00000440874	intact:EBI-10082|uniprotkb:D3DLR3|ensemblfungi:YER015W	psi-mi:o95197-3(display_long)|uniprotkb:RTN3(gene name)|psi-mi:RTN3(display_short)|uniprotkb:ASYIP(gene name synonym)|uniprotkb:Homolog of ASY protein(gene name synonym)|uniprotkb:NSPL2(gene name synonym)|uniprotkb:Neuroendocrine-specific protein-like 2(gene name synonym)|uniprotkb:Neuroendocrine-specific protein-like II(gene name synonym)|uniprotkb:A1(isoform synonym)|uniprotkb:B1(isoform synonym)	psi-mi:lcf2_yeast(display_long)|uniprotkb:YER015W(locus name)|uniprotkb:FAA2(gene name)|psi-mi:FAA2(display_short)|uniprotkb:FAM1(gene name synonym)|uniprotkb:Long-chain acyl-CoA synthetase 2(gene name synonym)|uniprotkb:Fatty acid activator 2(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11529846|imex:IM-24995-785	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000133318(gene)|ensembl:ENST00000537981(transcript)|intact:EBI-740467(isoform-parent)|uniprotkb:O95197-3(isoform-parent)|entrezgene/locuslink:10313(identity)	sgd:S000000817|ensemblfungi:YER015W_mRNA(transcript)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0004467"(long-chain fatty acid-CoA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0015910"(long-chain fatty acid import into peroxisome)|go:"GO:0015916"(fatty-acyl-CoA transport)|go:"GO:0016020"(membrane)|go:"GO:0031956"(medium-chain fatty acid-CoA ligase activity)|go:"GO:0031957"(very long-chain fatty acid-CoA ligase activity)|go:"GO:0042760"(very long-chain fatty acid catabolic process)|go:"GO:0102391"(decanoate-CoA ligase activity)|ensemblfungi:YER015W(gene)|interpro:IPR020845|interpro:IPR000873(AMP-dependent synthetase and ligase)|reactome:R-SCE-75876|refseq:NP_010931.3|dip:DIP-6565N|sgd:YER015W(identity)	-	-	crc64:1E023C18682805BC	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:+TJnANu85CM52dRZ6s+hYMlUABE9606	rogid:N0W+wPvCsl01y0k8hJZ156LztOo559292	intact-crc:7CE6605530EB255B|rigid:x+n4ZW7+LM8GqBUsDoGUzPA9Vc8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P39518	uniprotkb:P22234	intact:EBI-10082|uniprotkb:D3DLR3|ensemblfungi:YER015W	intact:EBI-712261|ensembl:ENSP00000264221|ensembl:ENSP00000421096|uniprotkb:E9PDH9|uniprotkb:Q68CQ5|intact:EBI-21352784	psi-mi:lcf2_yeast(display_long)|uniprotkb:YER015W(locus name)|uniprotkb:FAA2(gene name)|psi-mi:FAA2(display_short)|uniprotkb:FAM1(gene name synonym)|uniprotkb:Long-chain acyl-CoA synthetase 2(gene name synonym)|uniprotkb:Fatty acid activator 2(gene name synonym)	psi-mi:pur6_human(display_long)|uniprotkb:PAICS(gene name)|psi-mi:PAICS(display_short)|uniprotkb:ADE2(gene name synonym)|uniprotkb:AIRC(gene name synonym)|uniprotkb:PAIS(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11529874|imex:IM-24995-788	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000000817|ensemblfungi:YER015W_mRNA(transcript)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0004467"(long-chain fatty acid-CoA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0015910"(long-chain fatty acid import into peroxisome)|go:"GO:0015916"(fatty-acyl-CoA transport)|go:"GO:0016020"(membrane)|go:"GO:0031956"(medium-chain fatty acid-CoA ligase activity)|go:"GO:0031957"(very long-chain fatty acid-CoA ligase activity)|go:"GO:0042760"(very long-chain fatty acid catabolic process)|go:"GO:0102391"(decanoate-CoA ligase activity)|ensemblfungi:YER015W(gene)|interpro:IPR020845|interpro:IPR000873(AMP-dependent synthetase and ligase)|reactome:R-SCE-75876|refseq:NP_010931.3|dip:DIP-6565N|sgd:YER015W(identity)	ensembl:ENSG00000128050(gene)|ensembl:ENST00000264221(transcript)|ensembl:ENST00000512576(transcript)|go:"GO:0004639"(phosphoribosylaminoimidazolesuccinocarboxamide synthase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006189"('de novo' IMP biosynthetic process)|go:"GO:0009113"(purine nucleobase biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043727"(5-amino-4-imidazole carboxylate lyase activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000031("1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase")|interpro:IPR018236|interpro:IPR028923|interpro:IPR033626|mint:P22234|rcsb pdb:2H31|rcsb pdb:6YB8|go:"GO:0004638"(phosphoribosylaminoimidazole carboxylase activity)|rcsb pdb:6YB9|reactome:R-HSA-73817|refseq:NP_001072992.1|refseq:NP_001072993.1|refseq:NP_006443.1|entrezgene/locuslink:10606(identity)	-	crc64:1E023C18682805BC	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:N0W+wPvCsl01y0k8hJZ156LztOo559292	rogid:aR4Xj14ZQrPiY8cldw5o9AvjkAo9606	intact-crc:B368490A7B7C0CBC|rigid:XQYQO3vd7kUaC61bqXSD4A5ow5k	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P39518	uniprotkb:P07910-2	intact:EBI-10082|uniprotkb:D3DLR3|ensemblfungi:YER015W	intact:EBI-5280084|ensembl:ENSP00000442816|ensembl:ENSP00000450544|ensembl:ENSP00000450725|ensembl:ENSP00000451176	psi-mi:lcf2_yeast(display_long)|uniprotkb:YER015W(locus name)|uniprotkb:FAA2(gene name)|psi-mi:FAA2(display_short)|uniprotkb:FAM1(gene name synonym)|uniprotkb:Long-chain acyl-CoA synthetase 2(gene name synonym)|uniprotkb:Fatty acid activator 2(gene name synonym)	psi-mi:p07910-2(display_long)|uniprotkb:HNRNPC(gene name)|psi-mi:HNRNPC(display_short)|uniprotkb:HNRPC(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11529864|imex:IM-24995-787	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000000817|ensemblfungi:YER015W_mRNA(transcript)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0004467"(long-chain fatty acid-CoA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0015910"(long-chain fatty acid import into peroxisome)|go:"GO:0015916"(fatty-acyl-CoA transport)|go:"GO:0016020"(membrane)|go:"GO:0031956"(medium-chain fatty acid-CoA ligase activity)|go:"GO:0031957"(very long-chain fatty acid-CoA ligase activity)|go:"GO:0042760"(very long-chain fatty acid catabolic process)|go:"GO:0102391"(decanoate-CoA ligase activity)|ensemblfungi:YER015W(gene)|interpro:IPR020845|interpro:IPR000873(AMP-dependent synthetase and ligase)|reactome:R-SCE-75876|refseq:NP_010931.3|dip:DIP-6565N|sgd:YER015W(identity)	uniprotkb:P07910-2(isoform-parent)|intact:EBI-357966(isoform-parent)|ensembl:ENSG00000092199(gene)|ensembl:ENST00000430246(transcript)|ensembl:ENST00000553300(transcript)|ensembl:ENST00000554969(transcript)|ensembl:ENST00000556897(transcript)|entrezgene/locuslink:3183(identity)	-	crc64:1E023C18682805BC	isoform-comment:Contains a phosphoserine at position 107. Contains a phosphoserine at position 108.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:N0W+wPvCsl01y0k8hJZ156LztOo559292	rogid:r7AhGozE3aHdynLr8DrXPRtOuyI9606	intact-crc:21373ECA8FD18548|rigid:Yh1FrBuSQDLkgkAtbCm/laXsAgQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O96006	uniprotkb:P39518	intact:EBI-740037|uniprotkb:Q96BY4|ensembl:ENSP00000370616|ensembl:ENSP00000370620|ensembl:ENSP00000370621|ensembl:ENSP00000498725	intact:EBI-10082|uniprotkb:D3DLR3|ensemblfungi:YER015W	psi-mi:zbed1_human(display_long)|uniprotkb:ZBED1(gene name)|psi-mi:ZBED1(display_short)|uniprotkb:ALTE(gene name synonym)|uniprotkb:DREF(gene name synonym)|uniprotkb:KIAA0785(gene name synonym)|uniprotkb:TRAMP(gene name synonym)|uniprotkb:dREF homolog(gene name synonym)|uniprotkb:Putative Ac-like transposable element(gene name synonym)|uniprotkb:DNA replication-related element-binding factor(gene name synonym)|uniprotkb:Zinc finger BED domain-containing protein 1(gene name synonym)|uniprotkb:hDREF(gene name synonym)	psi-mi:lcf2_yeast(display_long)|uniprotkb:YER015W(locus name)|uniprotkb:FAA2(gene name)|psi-mi:FAA2(display_short)|uniprotkb:FAM1(gene name synonym)|uniprotkb:Long-chain acyl-CoA synthetase 2(gene name synonym)|uniprotkb:Fatty acid activator 2(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11529855|imex:IM-24995-786	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164606.1|refseq:NP_001164607.1|refseq:NP_004720.1|ensembl:ENSG00000214717(gene)|ensembl:ENST00000381218(transcript)|ensembl:ENST00000381222(transcript)|ensembl:ENST00000381223(transcript)|ensembl:ENST00000652001(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0031965"(nuclear membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044828"(negative regulation by host of viral genome replication)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0061665"(SUMO ligase activity)|go:"GO:1990466"(protein autosumoylation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003656(Zinc finger, BED-type predicted)|interpro:IPR008906(HAT dimerisation)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR036236|mint:O96006|rcsb pdb:2CT5|reactome:R-HSA-4551638|go:"GO:0005813"(centrosome)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016605"(PML body)|entrezgene/locuslink:9189(identity)	sgd:S000000817|ensemblfungi:YER015W_mRNA(transcript)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0004467"(long-chain fatty acid-CoA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0015910"(long-chain fatty acid import into peroxisome)|go:"GO:0015916"(fatty-acyl-CoA transport)|go:"GO:0016020"(membrane)|go:"GO:0031956"(medium-chain fatty acid-CoA ligase activity)|go:"GO:0031957"(very long-chain fatty acid-CoA ligase activity)|go:"GO:0042760"(very long-chain fatty acid catabolic process)|go:"GO:0102391"(decanoate-CoA ligase activity)|ensemblfungi:YER015W(gene)|interpro:IPR020845|interpro:IPR000873(AMP-dependent synthetase and ligase)|reactome:R-SCE-75876|refseq:NP_010931.3|dip:DIP-6565N|sgd:YER015W(identity)	-	-	crc64:1E023C18682805BC	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:jl97ZV2Kz5YAmQKktWt/wk7OkRw9606	rogid:N0W+wPvCsl01y0k8hJZ156LztOo559292	intact-crc:9BF23AA858BD7721|rigid:sZdkYiOSON76+GVlp5u9S9LSf58	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O76083-2	uniprotkb:P39518	intact:EBI-11524542|ensembl:ENSP00000335242	intact:EBI-10082|uniprotkb:D3DLR3|ensemblfungi:YER015W	psi-mi:o76083-2(display_long)|uniprotkb:PDE9A(gene name)|psi-mi:PDE9A(display_short)	psi-mi:lcf2_yeast(display_long)|uniprotkb:YER015W(locus name)|uniprotkb:FAA2(gene name)|psi-mi:FAA2(display_short)|uniprotkb:FAM1(gene name synonym)|uniprotkb:Long-chain acyl-CoA synthetase 2(gene name synonym)|uniprotkb:Fatty acid activator 2(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11529837|imex:IM-24995-784	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-742764(isoform-parent)|ensembl:ENSG00000160191(gene)|ensembl:ENST00000335512(transcript)|uniprotkb:O76083-2(isoform-parent)|entrezgene/locuslink:5152(identity)	sgd:S000000817|ensemblfungi:YER015W_mRNA(transcript)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0004467"(long-chain fatty acid-CoA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0015910"(long-chain fatty acid import into peroxisome)|go:"GO:0015916"(fatty-acyl-CoA transport)|go:"GO:0016020"(membrane)|go:"GO:0031956"(medium-chain fatty acid-CoA ligase activity)|go:"GO:0031957"(very long-chain fatty acid-CoA ligase activity)|go:"GO:0042760"(very long-chain fatty acid catabolic process)|go:"GO:0102391"(decanoate-CoA ligase activity)|ensemblfungi:YER015W(gene)|interpro:IPR020845|interpro:IPR000873(AMP-dependent synthetase and ligase)|reactome:R-SCE-75876|refseq:NP_010931.3|dip:DIP-6565N|sgd:YER015W(identity)	-	-	crc64:1E023C18682805BC	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:nTzgeYGOwTM/7VJUgxSnlnDiCFo9606	rogid:N0W+wPvCsl01y0k8hJZ156LztOo559292	intact-crc:2F93D4AC42ACDC8E|rigid:Dk/8xP4LKaNsYTJltvWK8HDs5Js	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P39518	uniprotkb:P49902	intact:EBI-10082|uniprotkb:D3DLR3|ensemblfungi:YER015W	intact:EBI-742084|uniprotkb:Q5JUV5|uniprotkb:D3DR91|ensembl:ENSP00000339479|ensembl:ENSP00000383960|ensembl:ENSP00000501689|ensembl:ENSP00000502205|ensembl:ENSP00000502679|ensembl:ENSP00000502801|uniprotkb:B7Z382	psi-mi:lcf2_yeast(display_long)|uniprotkb:YER015W(locus name)|uniprotkb:FAA2(gene name)|psi-mi:FAA2(display_short)|uniprotkb:FAM1(gene name synonym)|uniprotkb:Long-chain acyl-CoA synthetase 2(gene name synonym)|uniprotkb:Fatty acid activator 2(gene name synonym)	psi-mi:5ntc_human(display_long)|uniprotkb:Cytosolic 5'-nucleotidase II(gene name synonym)|uniprotkb:NT5C2(gene name)|psi-mi:NT5C2(display_short)|uniprotkb:NT5B(gene name synonym)|uniprotkb:NT5CP(gene name synonym)|uniprotkb:PNT5(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11529893|imex:IM-24995-790	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000000817|ensemblfungi:YER015W_mRNA(transcript)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0004467"(long-chain fatty acid-CoA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0015910"(long-chain fatty acid import into peroxisome)|go:"GO:0015916"(fatty-acyl-CoA transport)|go:"GO:0016020"(membrane)|go:"GO:0031956"(medium-chain fatty acid-CoA ligase activity)|go:"GO:0031957"(very long-chain fatty acid-CoA ligase activity)|go:"GO:0042760"(very long-chain fatty acid catabolic process)|go:"GO:0102391"(decanoate-CoA ligase activity)|ensemblfungi:YER015W(gene)|interpro:IPR020845|interpro:IPR000873(AMP-dependent synthetase and ligase)|reactome:R-SCE-75876|refseq:NP_010931.3|dip:DIP-6565N|sgd:YER015W(identity)	ensembl:ENST00000675326(transcript)|refseq:NP_001127845.1|refseq:NP_036361.1|ensembl:ENSG00000076685(gene)|ensembl:ENST00000343289(transcript)|ensembl:ENST00000404739(transcript)|ensembl:ENST00000674696(transcript)|ensembl:ENST00000676449(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0005829"(cytosol)|go:"GO:0006204"(IMP catabolic process)|go:"GO:0008253"(5'-nucleotidase activity)|go:"GO:0019428"(allantoin biosynthetic process)|go:"GO:0046040"(IMP metabolic process)|go:"GO:0046085"(adenosine metabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0050483"(IMP 5'-nucleotidase activity)|interpro:IPR008380(HAD-superfamily hydrolase, subfamily IG, 5'-nucleotidase)|interpro:IPR016695(Purine 5'-nucleotidase)|interpro:IPR023214|interpro:IPR036412|mint:P49902|rcsb pdb:2J2C|rcsb pdb:2JC9|rcsb pdb:2JCM|rcsb pdb:2XCV|rcsb pdb:2XCW|rcsb pdb:2XCX|rcsb pdb:2XJB|rcsb pdb:2XJC|rcsb pdb:2XJD|rcsb pdb:2XJE|rcsb pdb:2XJF|rcsb pdb:4H4B|rcsb pdb:5CQZ|rcsb pdb:5CR7|rcsb pdb:5K7Y|rcsb pdb:5L4Z|rcsb pdb:5L50|rcsb pdb:5OPK|rcsb pdb:5OPL|rcsb pdb:5OPM|rcsb pdb:5OPN|rcsb pdb:5OPO|rcsb pdb:5OPP|rcsb pdb:6DD3|rcsb pdb:6DDB|rcsb pdb:6DDC|rcsb pdb:6DDH|rcsb pdb:6DDK|rcsb pdb:6DDL|ensembl:ENST00000676428(transcript)|rcsb pdb:6DDO|rcsb pdb:6DDQ|rcsb pdb:6DDX|rcsb pdb:6DDY|rcsb pdb:6DDZ|rcsb pdb:6DE0|rcsb pdb:6DE1|rcsb pdb:6DE2|rcsb pdb:6DE3|rcsb pdb:6FIR|rcsb pdb:6FIS|rcsb pdb:6FIU|rcsb pdb:6FIW|rcsb pdb:6FXH|reactome:R-HSA-2161541|reactome:R-HSA-74259|refseq:XP_005269693.1|refseq:XP_005269696.1|entrezgene/locuslink:22978(identity)	-	crc64:1E023C18682805BC	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:N0W+wPvCsl01y0k8hJZ156LztOo559292	rogid:5CDp+/pOJ1IRk/ndDr4SGP0Ext89606	intact-crc:21B13DEFC64AB4FF|rigid:W9yB3Ioq/6qjAeSCgael0VrS98k	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q13137	uniprotkb:P39518	intact:EBI-739580|uniprotkb:B4DDC4|uniprotkb:E7ENK0|uniprotkb:Q53FQ5|uniprotkb:Q53HB5|uniprotkb:Q6IBN9|uniprotkb:Q9BTF7|uniprotkb:B2RBT0|ensembl:ENSP00000258947|uniprotkb:B4E0C0|uniprotkb:E7ETP5|uniprotkb:B4DDT4|uniprotkb:B4DP36|uniprotkb:E9PBE5	intact:EBI-10082|uniprotkb:D3DLR3|ensemblfungi:YER015W	psi-mi:caco2_human(display_long)|uniprotkb:CALCOCO2(gene name)|psi-mi:CALCOCO2(display_short)|uniprotkb:NDP52(gene name synonym)|uniprotkb:Nuclear domain 10 protein NDP52(gene name synonym)|uniprotkb:Antigen nuclear dot 52 kDa protein(gene name synonym)|uniprotkb:Nuclear dot protein 52(gene name synonym)	psi-mi:lcf2_yeast(display_long)|uniprotkb:YER015W(locus name)|uniprotkb:FAA2(gene name)|psi-mi:FAA2(display_short)|uniprotkb:FAM1(gene name synonym)|uniprotkb:Long-chain acyl-CoA synthetase 2(gene name synonym)|uniprotkb:Fatty acid activator 2(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11529902|imex:IM-24995-791	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001248319.1|refseq:NP_001248320.1|refseq:NP_001248322.1|refseq:NP_005822.1|ensembl:ENSG00000136436(gene)|ensembl:ENST00000258947(transcript)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016032"(viral process)|go:"GO:0016605"(PML body)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0098792"(xenophagy)|go:"GO:1901098"(positive regulation of autophagosome maturation)|interpro:IPR041611|interpro:IPR041641|mint:Q13137|rcsb pdb:2MXP|rcsb pdb:3VVV|rcsb pdb:3VVW|rcsb pdb:4GXL|rcsb pdb:4HAN|rcsb pdb:4XKL|rcsb pdb:5AAQ|rcsb pdb:5Z7A|rcsb pdb:5Z7L|refseq:NP_001248324.1|dip:DIP-57534N|entrezgene/locuslink:10241(identity)	sgd:S000000817|ensemblfungi:YER015W_mRNA(transcript)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0004467"(long-chain fatty acid-CoA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0015910"(long-chain fatty acid import into peroxisome)|go:"GO:0015916"(fatty-acyl-CoA transport)|go:"GO:0016020"(membrane)|go:"GO:0031956"(medium-chain fatty acid-CoA ligase activity)|go:"GO:0031957"(very long-chain fatty acid-CoA ligase activity)|go:"GO:0042760"(very long-chain fatty acid catabolic process)|go:"GO:0102391"(decanoate-CoA ligase activity)|ensemblfungi:YER015W(gene)|interpro:IPR020845|interpro:IPR000873(AMP-dependent synthetase and ligase)|reactome:R-SCE-75876|refseq:NP_010931.3|dip:DIP-6565N|sgd:YER015W(identity)	-	crc64:609B121DA1A9DCB8	crc64:1E023C18682805BC	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:N/GPJUGBK+Dh5Cg+csmafphuo9M9606	rogid:N0W+wPvCsl01y0k8hJZ156LztOo559292	intact-crc:8ACF58D796AB7A8C|rigid:JuBP4SQdwbjIksL/sT7y/Ft556A	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q13422-7	uniprotkb:P39518	intact:EBI-11522367|ensembl:ENSP00000352123|ensembl:ENSP00000413025	intact:EBI-10082|uniprotkb:D3DLR3|ensemblfungi:YER015W	psi-mi:q13422-7(display_long)|uniprotkb:IKZF1(gene name)|psi-mi:IKZF1(display_short)|uniprotkb:IK1(gene name synonym)|uniprotkb:IKAROS(gene name synonym)|uniprotkb:Ikaros family zinc finger protein 1(gene name synonym)|uniprotkb:LYF1(gene name synonym)|uniprotkb:Lymphoid transcription factor LyF-1(gene name synonym)|uniprotkb:ZNFN1A1(gene name synonym)	psi-mi:lcf2_yeast(display_long)|uniprotkb:YER015W(locus name)|uniprotkb:FAA2(gene name)|psi-mi:FAA2(display_short)|uniprotkb:FAM1(gene name synonym)|uniprotkb:Long-chain acyl-CoA synthetase 2(gene name synonym)|uniprotkb:Fatty acid activator 2(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11529911|imex:IM-24995-792	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-745305(isoform-parent)|ensembl:ENSG00000185811(gene)|ensembl:ENST00000359197(transcript)|ensembl:ENST00000439701(transcript)|uniprotkb:Q13422-7(isoform-parent)|entrezgene/locuslink:10320(identity)	sgd:S000000817|ensemblfungi:YER015W_mRNA(transcript)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0004467"(long-chain fatty acid-CoA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0015910"(long-chain fatty acid import into peroxisome)|go:"GO:0015916"(fatty-acyl-CoA transport)|go:"GO:0016020"(membrane)|go:"GO:0031956"(medium-chain fatty acid-CoA ligase activity)|go:"GO:0031957"(very long-chain fatty acid-CoA ligase activity)|go:"GO:0042760"(very long-chain fatty acid catabolic process)|go:"GO:0102391"(decanoate-CoA ligase activity)|ensemblfungi:YER015W(gene)|interpro:IPR020845|interpro:IPR000873(AMP-dependent synthetase and ligase)|reactome:R-SCE-75876|refseq:NP_010931.3|dip:DIP-6565N|sgd:YER015W(identity)	-	-	crc64:1E023C18682805BC	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:ou/ovXYoMneBNVp4pj38VxenfyY9606	rogid:N0W+wPvCsl01y0k8hJZ156LztOo559292	intact-crc:14BEF34F1B4693B3|rigid:tr2RoegfWLDzWC6PNjVH9qBlufc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P39518	uniprotkb:Q15041	intact:EBI-10082|uniprotkb:D3DLR3|ensemblfungi:YER015W	intact:EBI-714543|ensembl:ENSP00000306788|uniprotkb:B7Z6S5|uniprotkb:B7Z791|uniprotkb:F5GXP4	psi-mi:lcf2_yeast(display_long)|uniprotkb:YER015W(locus name)|uniprotkb:FAA2(gene name)|psi-mi:FAA2(display_short)|uniprotkb:FAM1(gene name synonym)|uniprotkb:Long-chain acyl-CoA synthetase 2(gene name synonym)|uniprotkb:Fatty acid activator 2(gene name synonym)	psi-mi:ar6p1_human(display_long)|uniprotkb:ARL6IP(gene name synonym)|uniprotkb:ARL6IP1(gene name)|psi-mi:ARL6IP1(display_short)|uniprotkb:KIAA0069(gene name synonym)|uniprotkb:ARMER(gene name synonym)|uniprotkb:Apoptotic regulator in the membrane of the endoplasmic reticulum(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11529920|imex:IM-24995-793	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000000817|ensemblfungi:YER015W_mRNA(transcript)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0004467"(long-chain fatty acid-CoA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0015910"(long-chain fatty acid import into peroxisome)|go:"GO:0015916"(fatty-acyl-CoA transport)|go:"GO:0016020"(membrane)|go:"GO:0031956"(medium-chain fatty acid-CoA ligase activity)|go:"GO:0031957"(very long-chain fatty acid-CoA ligase activity)|go:"GO:0042760"(very long-chain fatty acid catabolic process)|go:"GO:0102391"(decanoate-CoA ligase activity)|ensemblfungi:YER015W(gene)|interpro:IPR020845|interpro:IPR000873(AMP-dependent synthetase and ligase)|reactome:R-SCE-75876|refseq:NP_010931.3|dip:DIP-6565N|sgd:YER015W(identity)	refseq:NP_055976.1|ensembl:ENSG00000170540(gene)|ensembl:ENST00000304414(transcript)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006613"(cotranslational protein targeting to membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0071787"(endoplasmic reticulum tubular network formation)|go:"GO:1903371"(regulation of endoplasmic reticulum tubular network organization)|go:"GO:1990809"(endoplasmic reticulum tubular network membrane organization)|interpro:IPR033301|mint:Q15041|go:"GO:0002038"(positive regulation of L-glutamate import across plasma membrane)|refseq:NP_001300787.1|entrezgene/locuslink:23204(identity)	-	crc64:1E023C18682805BC	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:N0W+wPvCsl01y0k8hJZ156LztOo559292	rogid:3fjkoyvUx25po7xsPcXgpjEeLJg9606	intact-crc:977DF71C39DF0AB5|rigid:ov9rVkwnhLHkf4vKK1snMQdp5sY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P35520	uniprotkb:P39518	intact:EBI-740135|uniprotkb:Q99425|uniprotkb:Q9BWC5|uniprotkb:B2R993|uniprotkb:D3DSK4|intact:EBI-14245939|ensembl:ENSP00000344460|ensembl:ENSP00000352643|ensembl:ENSP00000381225|ensembl:ENSP00000381231	intact:EBI-10082|uniprotkb:D3DLR3|ensemblfungi:YER015W	psi-mi:cbs_human(display_long)|uniprotkb:CBS(gene name)|psi-mi:CBS(display_short)|uniprotkb:Serine sulfhydrase(gene name synonym)|uniprotkb:Beta-thionase(gene name synonym)	psi-mi:lcf2_yeast(display_long)|uniprotkb:YER015W(locus name)|uniprotkb:FAA2(gene name)|psi-mi:FAA2(display_short)|uniprotkb:FAM1(gene name synonym)|uniprotkb:Long-chain acyl-CoA synthetase 2(gene name synonym)|uniprotkb:Fatty acid activator 2(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11529883|imex:IM-24995-789	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000062.1|refseq:NP_001171479.1|refseq:NP_001171480.1|ensembl:ENSG00000160200(gene)|ensembl:ENST00000352178(transcript)|ensembl:ENST00000359624(transcript)|ensembl:ENST00000398158(transcript)|go:"GO:0004122"(cystathionine beta-synthase activity)|ensembl:ENST00000398165(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006535"(cysteine biosynthetic process from serine)|go:"GO:0006563"(L-serine metabolic process)|go:"GO:0006565"(L-serine catabolic process)|go:"GO:0019343"(cysteine biosynthetic process via cystathionine)|go:"GO:0019344"(cysteine biosynthetic process)|go:"GO:0019346"(transsulfuration)|go:"GO:0019448"(L-cysteine catabolic process)|go:"GO:0019825"(oxygen binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0020037"(heme binding)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042262"(DNA protection)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043418"(homocysteine catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0050421"("nitrite reductase (NO-forming) activity")|go:"GO:0050667"(homocysteine metabolic process)|go:"GO:0070025"(carbon monoxide binding)|go:"GO:0070026"(nitric oxide binding)|go:"GO:0070814"(hydrogen sulfide biosynthetic process)|go:"GO:0072341"(modified amino acid binding)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR001216(Cysteine synthase/cystathionine beta-synthase P-phosphate-binding site)|interpro:IPR001926(Pyridoxal phosphate-dependent enzyme, beta subunit)|interpro:IPR005857(Cystathionine beta-synthase)|interpro:IPR036052|mint:P35520|rcsb pdb:1JBQ|rcsb pdb:1M54|rcsb pdb:4COO|rcsb pdb:4L0D|rcsb pdb:4L27|rcsb pdb:4L28|rcsb pdb:4L3V|rcsb pdb:4PCU|rcsb pdb:4UUU|rcsb pdb:5MMS|reactome:R-HSA-1614603|reactome:R-HSA-2408508|refseq:XP_011528079.1|refseq:XP_011528083.1|refseq:XP_011528084.1|refseq:XP_011544396.1|refseq:XP_011544397.1|refseq:XP_011544399.1|refseq:XP_011544400.1|refseq:XP_011544401.1|refseq:NP_001307227.1|refseq:NP_001308002.1|refseq:XP_016883700.1|refseq:XP_016883701.1|refseq:XP_016883702.1|refseq:XP_016883703.1|refseq:XP_016883704.1|refseq:XP_016883705.1|refseq:XP_016883706.1|refseq:XP_016883707.1|refseq:XP_016883978.1|refseq:XP_016883979.1|refseq:XP_016883980.1|refseq:XP_016883981.1|entrezgene/locuslink:875(identity)	sgd:S000000817|ensemblfungi:YER015W_mRNA(transcript)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0004467"(long-chain fatty acid-CoA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0015910"(long-chain fatty acid import into peroxisome)|go:"GO:0015916"(fatty-acyl-CoA transport)|go:"GO:0016020"(membrane)|go:"GO:0031956"(medium-chain fatty acid-CoA ligase activity)|go:"GO:0031957"(very long-chain fatty acid-CoA ligase activity)|go:"GO:0042760"(very long-chain fatty acid catabolic process)|go:"GO:0102391"(decanoate-CoA ligase activity)|ensemblfungi:YER015W(gene)|interpro:IPR020845|interpro:IPR000873(AMP-dependent synthetase and ligase)|reactome:R-SCE-75876|refseq:NP_010931.3|dip:DIP-6565N|sgd:YER015W(identity)	-	-	crc64:1E023C18682805BC	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:f9eo0cPOHppVY7Nqejag3YyK18s9606	rogid:N0W+wPvCsl01y0k8hJZ156LztOo559292	intact-crc:C1C64F3B7E758230|rigid:ngkmAHGpWOuDy4j3IBLXuwd8SN4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P39518	uniprotkb:Q96BR9	intact:EBI-10082|uniprotkb:D3DLR3|ensemblfungi:YER015W	intact:EBI-742740|uniprotkb:Q8IUL5|uniprotkb:Q8IWR9|uniprotkb:Q8N2Y5|uniprotkb:Q96BX0|ensembl:ENSP00000362609	psi-mi:lcf2_yeast(display_long)|uniprotkb:YER015W(locus name)|uniprotkb:FAA2(gene name)|psi-mi:FAA2(display_short)|uniprotkb:FAM1(gene name synonym)|uniprotkb:Long-chain acyl-CoA synthetase 2(gene name synonym)|uniprotkb:Fatty acid activator 2(gene name synonym)	psi-mi:zbt8a_human(display_long)|uniprotkb:ZBTB8A(gene name)|psi-mi:ZBTB8A(display_short)|uniprotkb:BOZF1(gene name synonym)|uniprotkb:BTB/POZ and zinc-finger domain-containing factor(gene name synonym)|uniprotkb:BTB/POZ and zinc-finger domains factor on chromosome 1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11529951|imex:IM-24995-796	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000000817|ensemblfungi:YER015W_mRNA(transcript)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0004467"(long-chain fatty acid-CoA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0015910"(long-chain fatty acid import into peroxisome)|go:"GO:0015916"(fatty-acyl-CoA transport)|go:"GO:0016020"(membrane)|go:"GO:0031956"(medium-chain fatty acid-CoA ligase activity)|go:"GO:0031957"(very long-chain fatty acid-CoA ligase activity)|go:"GO:0042760"(very long-chain fatty acid catabolic process)|go:"GO:0102391"(decanoate-CoA ligase activity)|ensemblfungi:YER015W(gene)|interpro:IPR020845|interpro:IPR000873(AMP-dependent synthetase and ligase)|reactome:R-SCE-75876|refseq:NP_010931.3|dip:DIP-6565N|sgd:YER015W(identity)	ensembl:ENSG00000160062(gene)|ensembl:ENST00000373510(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|refseq:NP_001035531.2|refseq:NP_001278425.1|entrezgene/locuslink:653121(identity)	-	crc64:1E023C18682805BC	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:N0W+wPvCsl01y0k8hJZ156LztOo559292	rogid:tsrPT2tHvuBryODKgRXnceXz9s09606	intact-crc:B19290EF94191CBC|rigid:Gr/sWGuaQeQTACIYn7TXknaBu6k	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8IUQ4-2	uniprotkb:P39518	intact:EBI-11522811|ensembl:ENSP00000349156	intact:EBI-10082|uniprotkb:D3DLR3|ensemblfungi:YER015W	psi-mi:q8iuq4-2(display_long)|uniprotkb:SIAH1(gene name)|psi-mi:SIAH1(display_short)|uniprotkb:HUMSIAH(gene name synonym)|uniprotkb:Seven in absentia homolog 1(gene name synonym)|uniprotkb:Siah-1a(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase SIAH1(gene name synonym)	psi-mi:lcf2_yeast(display_long)|uniprotkb:YER015W(locus name)|uniprotkb:FAA2(gene name)|psi-mi:FAA2(display_short)|uniprotkb:FAM1(gene name synonym)|uniprotkb:Long-chain acyl-CoA synthetase 2(gene name synonym)|uniprotkb:Fatty acid activator 2(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11529929|imex:IM-24995-794	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-747107(isoform-parent)|ensembl:ENSG00000196470(gene)|ensembl:ENST00000356721(transcript)|uniprotkb:Q8IUQ4-2(isoform-parent)|entrezgene/locuslink:6477(identity)	sgd:S000000817|ensemblfungi:YER015W_mRNA(transcript)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0004467"(long-chain fatty acid-CoA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0015910"(long-chain fatty acid import into peroxisome)|go:"GO:0015916"(fatty-acyl-CoA transport)|go:"GO:0016020"(membrane)|go:"GO:0031956"(medium-chain fatty acid-CoA ligase activity)|go:"GO:0031957"(very long-chain fatty acid-CoA ligase activity)|go:"GO:0042760"(very long-chain fatty acid catabolic process)|go:"GO:0102391"(decanoate-CoA ligase activity)|ensemblfungi:YER015W(gene)|interpro:IPR020845|interpro:IPR000873(AMP-dependent synthetase and ligase)|reactome:R-SCE-75876|refseq:NP_010931.3|dip:DIP-6565N|sgd:YER015W(identity)	-	-	crc64:1E023C18682805BC	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:M4q06jVbWuq1mGMXvtuFBaMEgZM9606	rogid:N0W+wPvCsl01y0k8hJZ156LztOo559292	intact-crc:5C6AB2EB25D27755|rigid:QY3qRKX+Ly4iEvVnVLbkyovBdqQ	false	sufficient binding region:32-313	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8N7W2-2	uniprotkb:P39518	intact:EBI-10181188|ensembl:ENSP00000367868	intact:EBI-10082|uniprotkb:D3DLR3|ensemblfungi:YER015W	psi-mi:q8n7w2-2(display_long)|uniprotkb:C10orf30(gene name synonym)|uniprotkb:BEND7(gene name)|psi-mi:BEND7(display_short)	psi-mi:lcf2_yeast(display_long)|uniprotkb:YER015W(locus name)|uniprotkb:FAA2(gene name)|psi-mi:FAA2(display_short)|uniprotkb:FAM1(gene name synonym)|uniprotkb:Long-chain acyl-CoA synthetase 2(gene name synonym)|uniprotkb:Fatty acid activator 2(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11529940|imex:IM-24995-795	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000165626(gene)|ensembl:ENST00000378605(transcript)|intact:EBI-743382(isoform-parent)|uniprotkb:Q8N7W2-2(isoform-parent)|entrezgene/locuslink:222389(identity)	sgd:S000000817|ensemblfungi:YER015W_mRNA(transcript)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0004467"(long-chain fatty acid-CoA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0015910"(long-chain fatty acid import into peroxisome)|go:"GO:0015916"(fatty-acyl-CoA transport)|go:"GO:0016020"(membrane)|go:"GO:0031956"(medium-chain fatty acid-CoA ligase activity)|go:"GO:0031957"(very long-chain fatty acid-CoA ligase activity)|go:"GO:0042760"(very long-chain fatty acid catabolic process)|go:"GO:0102391"(decanoate-CoA ligase activity)|ensemblfungi:YER015W(gene)|interpro:IPR020845|interpro:IPR000873(AMP-dependent synthetase and ligase)|reactome:R-SCE-75876|refseq:NP_010931.3|dip:DIP-6565N|sgd:YER015W(identity)	-	-	crc64:1E023C18682805BC	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:p6qrTn80hLyVU0W2Tvwn50Q4m5I9606	rogid:N0W+wPvCsl01y0k8hJZ156LztOo559292	intact-crc:035DD98CA1346331|rigid:EjK37wZoiPafiy8nv3vpz9zYSac	false	sufficient binding region:10-374	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P39682	uniprotkb:O14641	intact:EBI-612|uniprotkb:D6VZC9|uniprotkb:E9P8Z1|ensemblfungi:YML046W	intact:EBI-740850|ensembl:ENSP00000005340|uniprotkb:Q53XM0|uniprotkb:D3DTN3	psi-mi:prp39_yeast(display_long)|uniprotkb:YM9827.06(orf name)|uniprotkb:YML046W(locus name)|uniprotkb:PRP39(gene name)|psi-mi:PRP39(display_short)	psi-mi:dvl2_human(display_long)|uniprotkb:DSH homolog 2(gene name synonym)|uniprotkb:DVL2(gene name)|psi-mi:DVL2(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11529996|imex:IM-24995-801	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013667.1|sgd:S000004509|dip:DIP-812N|mint:P39682|ensemblfungi:YML046W(gene)|ensemblfungi:YML046W_mRNA(transcript)|go:"GO:0000243"(commitment complex)|go:"GO:0000395"(mRNA 5'-splice site recognition)|go:"GO:0005685"(U1 snRNP)|go:"GO:0071004"(U2-type prespliceosome)|interpro:IPR003107(RNA-processing protein, HAT helix)|interpro:IPR011990(Tetratricopeptide-like helical)|rcsb pdb:5ZWN|rcsb pdb:6G90|rcsb pdb:6N7P|rcsb pdb:6N7R|rcsb pdb:6N7X|sgd:YML046W(identity)	refseq:NP_004413.1|ensembl:ENSG00000004975(gene)|ensembl:ENST00000005340(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005109"(frizzled binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0007507"(heart development)|go:"GO:0016235"(aggresome)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044340"(canonical Wnt signaling pathway involved in regulation of cell proliferation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0150012"(positive regulation of neuron projection arborization)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008341(Dishevelled-2 region)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:O14641|rcsb pdb:2REY|rcsb pdb:3CBX|rcsb pdb:3CBY|rcsb pdb:3CBZ|rcsb pdb:3CC0|rcsb pdb:4WIP|rcsb pdb:5LNP|rcsb pdb:5SUY|rcsb pdb:5SUZ|rcsb pdb:6IW3|rcsb pdb:6JCK|reactome:R-HSA-201681|reactome:R-HSA-201688|reactome:R-HSA-2028269|reactome:R-HSA-4086400|reactome:R-HSA-4608870|reactome:R-HSA-4641258|reactome:R-HSA-4641262|reactome:R-HSA-5099900|reactome:R-HSA-5368598|reactome:R-HSA-5663220|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9673324|ensembl:ENSP00000005340|dip:DIP-34433N|entrezgene/locuslink:1856(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:urVLzQFKnYT1bYOs3yRd9dd7lMk559292	rogid:2Vdc8oRnT4Mz/j+EXQXrL3AszOc9606	intact-crc:AB8E459C9F490415|rigid:Pfvm9smdLdGgF8hkioD1aRn7hOQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P39518	uniprotkb:Q9UI14	intact:EBI-10082|uniprotkb:D3DLR3|ensemblfungi:YER015W	intact:EBI-712367|ensembl:ENSP00000222008|uniprotkb:Q7Z4Y2|uniprotkb:Q9Y3R1	psi-mi:lcf2_yeast(display_long)|uniprotkb:YER015W(locus name)|uniprotkb:FAA2(gene name)|psi-mi:FAA2(display_short)|uniprotkb:FAM1(gene name synonym)|uniprotkb:Long-chain acyl-CoA synthetase 2(gene name synonym)|uniprotkb:Fatty acid activator 2(gene name synonym)	psi-mi:praf1_human(display_long)|uniprotkb:PRA1 family protein 1(gene name synonym)|uniprotkb:RABAC1(gene name)|psi-mi:RABAC1(display_short)|uniprotkb:PRA1(gene name synonym)|uniprotkb:PRAF1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11529978|imex:IM-24995-799	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000000817|ensemblfungi:YER015W_mRNA(transcript)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0004467"(long-chain fatty acid-CoA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0015910"(long-chain fatty acid import into peroxisome)|go:"GO:0015916"(fatty-acyl-CoA transport)|go:"GO:0016020"(membrane)|go:"GO:0031956"(medium-chain fatty acid-CoA ligase activity)|go:"GO:0031957"(very long-chain fatty acid-CoA ligase activity)|go:"GO:0042760"(very long-chain fatty acid catabolic process)|go:"GO:0102391"(decanoate-CoA ligase activity)|ensemblfungi:YER015W(gene)|interpro:IPR020845|interpro:IPR000873(AMP-dependent synthetase and ligase)|reactome:R-SCE-75876|refseq:NP_010931.3|dip:DIP-6565N|sgd:YER015W(identity)	refseq:NP_006414.2|ensembl:ENSG00000105404(gene)|ensembl:ENST00000222008(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0070064"(proline-rich region binding)|interpro:IPR004895(Prenylated rab acceptor PRA1)|mint:Q9UI14|entrezgene/locuslink:10567(identity)	-	crc64:1E023C18682805BC	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:N0W+wPvCsl01y0k8hJZ156LztOo559292	rogid:WS2rUY7yXRbR7pqWgfUCbnEiDbg9606	intact-crc:0C74E7A365314946|rigid:jPhhAt1Bsy7WNtT3Ax4kIVJhUQo	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9NPJ6	uniprotkb:P39518	intact:EBI-394607|uniprotkb:Q9BS95|uniprotkb:Q9NYR5|uniprotkb:Q53GB4|uniprotkb:Q53H68|uniprotkb:Q5T912|uniprotkb:Q6FHC4|uniprotkb:Q6IA79|uniprotkb:B4DX67|ensembl:ENSP00000258648	intact:EBI-10082|uniprotkb:D3DLR3|ensemblfungi:YER015W	psi-mi:med4_human(display_long)|uniprotkb:HSPC126(orf name)|uniprotkb:DRIP36(gene name synonym)|uniprotkb:MED4(gene name)|psi-mi:MED4(display_short)|uniprotkb:ARC36(gene name synonym)|uniprotkb:Mediator complex subunit 4(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex 36 kDa component(gene name synonym)|uniprotkb:Activator-recruited cofactor 36 kDa component(gene name synonym)|uniprotkb:TRAP/SMCC/PC2 subunit p36 subunit(gene name synonym)|uniprotkb:VDRIP(gene name synonym)	psi-mi:lcf2_yeast(display_long)|uniprotkb:YER015W(locus name)|uniprotkb:FAA2(gene name)|psi-mi:FAA2(display_short)|uniprotkb:FAM1(gene name synonym)|uniprotkb:Long-chain acyl-CoA synthetase 2(gene name synonym)|uniprotkb:Fatty acid activator 2(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11529969|imex:IM-24995-798	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001257558.1|refseq:NP_054885.1|ensembl:ENSG00000136146(gene)|ensembl:ENST00000258648(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0070847"(core mediator complex)|interpro:IPR019258|mint:Q9NPJ6|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|entrezgene/locuslink:29079(identity)	sgd:S000000817|ensemblfungi:YER015W_mRNA(transcript)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0004467"(long-chain fatty acid-CoA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0015910"(long-chain fatty acid import into peroxisome)|go:"GO:0015916"(fatty-acyl-CoA transport)|go:"GO:0016020"(membrane)|go:"GO:0031956"(medium-chain fatty acid-CoA ligase activity)|go:"GO:0031957"(very long-chain fatty acid-CoA ligase activity)|go:"GO:0042760"(very long-chain fatty acid catabolic process)|go:"GO:0102391"(decanoate-CoA ligase activity)|ensemblfungi:YER015W(gene)|interpro:IPR020845|interpro:IPR000873(AMP-dependent synthetase and ligase)|reactome:R-SCE-75876|refseq:NP_010931.3|dip:DIP-6565N|sgd:YER015W(identity)	-	-	crc64:1E023C18682805BC	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Bept2Oec50gruA9e4pf+eEUiANM9606	rogid:N0W+wPvCsl01y0k8hJZ156LztOo559292	intact-crc:65735DB614261770|rigid:i1z/5yTyyQ+u3OtNUB+vUE5MzCI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P39518	uniprotkb:Q96KN7-4	intact:EBI-10082|uniprotkb:D3DLR3|ensemblfungi:YER015W	intact:EBI-11525164|ensembl:ENSP00000372391	psi-mi:lcf2_yeast(display_long)|uniprotkb:YER015W(locus name)|uniprotkb:FAA2(gene name)|psi-mi:FAA2(display_short)|uniprotkb:FAM1(gene name synonym)|uniprotkb:Long-chain acyl-CoA synthetase 2(gene name synonym)|uniprotkb:Fatty acid activator 2(gene name synonym)	psi-mi:q96kn7-4(display_long)|uniprotkb:RPGRIP1(gene name)|psi-mi:RPGRIP1(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11529960|imex:IM-24995-797	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000000817|ensemblfungi:YER015W_mRNA(transcript)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0004467"(long-chain fatty acid-CoA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0015910"(long-chain fatty acid import into peroxisome)|go:"GO:0015916"(fatty-acyl-CoA transport)|go:"GO:0016020"(membrane)|go:"GO:0031956"(medium-chain fatty acid-CoA ligase activity)|go:"GO:0031957"(very long-chain fatty acid-CoA ligase activity)|go:"GO:0042760"(very long-chain fatty acid catabolic process)|go:"GO:0102391"(decanoate-CoA ligase activity)|ensemblfungi:YER015W(gene)|interpro:IPR020845|interpro:IPR000873(AMP-dependent synthetase and ligase)|reactome:R-SCE-75876|refseq:NP_010931.3|dip:DIP-6565N|sgd:YER015W(identity)	intact:EBI-1050213(isoform-parent)|ensembl:ENSG00000092200(gene)|ensembl:ENST00000382933(transcript)|uniprotkb:Q96KN7-4(isoform-parent)|entrezgene/locuslink:57096(identity)	-	crc64:1E023C18682805BC	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:N0W+wPvCsl01y0k8hJZ156LztOo559292	rogid:Xy0433uM/nWhWLM/EsfESPJDIy49606	intact-crc:6D9271D9586F2E7A|rigid:/6AjyN53VR+VGsZRy2aKUCAVJLw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9BSE2	uniprotkb:P39547	intact:EBI-8649725|ensembl:ENSP00000295694|ensembl:ENSP00000384748|intact:MINT-8163648|uniprotkb:D3DVB8|uniprotkb:B2RE22	intact:EBI-20760|uniprotkb:D6VPM9|ensemblfungi:YAR027W	psi-mi:tmm79_human(display_long)|uniprotkb:MATT(gene name synonym)|uniprotkb:TMEM79(gene name)|psi-mi:TMEM79(display_short)|uniprotkb:Mattrin(gene name synonym)	psi-mi:uip3_yeast(display_long)|uniprotkb:UIP3(gene name)|psi-mi:UIP3(display_short)|uniprotkb:YAR027W(locus name)|uniprotkb:FUN55(orf name)|uniprotkb:DUP240 protein UIP3(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11529987|imex:IM-24995-800	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000163472(gene)|ensembl:ENST00000295694(transcript)|ensembl:ENST00000405535(transcript)|go:"GO:0002070"(epithelial cell maturation)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031069"(hair follicle morphogenesis)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0042335"(cuticle development)|go:"GO:0042802"(identical protein binding)|go:"GO:0045055"(regulated exocytosis)|go:"GO:0045684"(positive regulation of epidermis development)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070268"(cornification)|mint:Q9BSE2|refseq:NP_115699.1|entrezgene/locuslink:84283(identity)	sgd:S000000075|refseq:NP_009414.1|ensemblfungi:YAR027W(gene)|ensemblfungi:YAR027W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031965"(nuclear membrane)|interpro:IPR001142(Yeast membrane protein DUP)|dip:DIP-2031N|sgd:YAR027W(identity)	-	comment:mint	crc64:9DBF29F9C2395AB2	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:QdmILKEdTJzJUhBdigw/4vC4R3o9606	rogid:2Eb82iBxbdvlroWw/nM4BQeiVIc559292	intact-crc:691DCF38CBC14843|rigid:9DZxVoVQDjwUMiByyxSNbVWEbJ0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96MA1	uniprotkb:P39682	intact:EBI-954466|uniprotkb:Q96SD2|ensembl:ENSP00000360500	intact:EBI-612|uniprotkb:D6VZC9|uniprotkb:E9P8Z1|ensemblfungi:YML046W	psi-mi:dmrtb_human(display_long)|uniprotkb:DMRTB1(gene name)|psi-mi:DMRTB1(display_short)	psi-mi:prp39_yeast(display_long)|uniprotkb:YM9827.06(orf name)|uniprotkb:YML046W(locus name)|uniprotkb:PRP39(gene name)|psi-mi:PRP39(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11530014|imex:IM-24995-803	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|ensembl:ENSG00000143006(gene)|ensembl:ENST00000371445(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007281"(germ cell development)|go:"GO:0007548"(sex differentiation)|go:"GO:0046872"(metal ion binding)|interpro:IPR001275(DM DNA-binding)|interpro:IPR026607|interpro:IPR036407|mint:Q96MA1|refseq:NP_149056.1|ensembl:ENSP00000360500|entrezgene/locuslink:63948(identity)	refseq:NP_013667.1|sgd:S000004509|dip:DIP-812N|mint:P39682|ensemblfungi:YML046W(gene)|ensemblfungi:YML046W_mRNA(transcript)|go:"GO:0000243"(commitment complex)|go:"GO:0000395"(mRNA 5'-splice site recognition)|go:"GO:0005685"(U1 snRNP)|go:"GO:0071004"(U2-type prespliceosome)|interpro:IPR003107(RNA-processing protein, HAT helix)|interpro:IPR011990(Tetratricopeptide-like helical)|rcsb pdb:5ZWN|rcsb pdb:6G90|rcsb pdb:6N7P|rcsb pdb:6N7R|rcsb pdb:6N7X|sgd:YML046W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:GU1xgsv/Oyy91PEorOlxBqAvIzc9606	rogid:urVLzQFKnYT1bYOs3yRd9dd7lMk559292	intact-crc:D54B0ED5BCDB0E42|rigid:FUMZ+VXl/dUFXcBRRDFQsjRZQLA	false	sufficient binding region:154-342	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P39682	uniprotkb:Q9NSC5	intact:EBI-612|uniprotkb:D6VZC9|uniprotkb:E9P8Z1|ensemblfungi:YML046W	intact:EBI-748420|uniprotkb:O14580|uniprotkb:O95350|uniprotkb:Q9NSB9|uniprotkb:Q9NSC0|intact:EBI-2557809|uniprotkb:E9PCW9|uniprotkb:Q9NSC1|intact:EBI-28972925|ensembl:ENSP00000376162|ensembl:ENSP00000439937|ensembl:ENSP00000446026|intact:EBI-10175777|uniprotkb:B2RA10	psi-mi:prp39_yeast(display_long)|uniprotkb:YM9827.06(orf name)|uniprotkb:YML046W(locus name)|uniprotkb:PRP39(gene name)|psi-mi:PRP39(display_short)	psi-mi:home3_human(display_long)|uniprotkb:HOMER3(gene name)|psi-mi:HOMER3(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11530025|imex:IM-24995-804	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013667.1|sgd:S000004509|dip:DIP-812N|mint:P39682|ensemblfungi:YML046W(gene)|ensemblfungi:YML046W_mRNA(transcript)|go:"GO:0000243"(commitment complex)|go:"GO:0000395"(mRNA 5'-splice site recognition)|go:"GO:0005685"(U1 snRNP)|go:"GO:0071004"(U2-type prespliceosome)|interpro:IPR003107(RNA-processing protein, HAT helix)|interpro:IPR011990(Tetratricopeptide-like helical)|rcsb pdb:5ZWN|rcsb pdb:6G90|rcsb pdb:6N7P|rcsb pdb:6N7R|rcsb pdb:6N7X|sgd:YML046W(identity)	ensembl:ENST00000221222|ensembl:ENSP00000221222|ensembl:ENSP00000376162|ensembl:ENST00000433218|ensembl:ENSP00000396154|ensembl:ENSP00000439937|ensembl:ENSP00000446026|ensembl:ENST00000594439|ensembl:ENSP00000471835|refseq:XP_006723006.1|refseq:XP_006723007.1|refseq:NP_001139193.1|refseq:NP_001139194.1|refseq:NP_004829.3|refseq:NP_001139196.1|ensembl:ENSG00000051128(gene)|ensembl:ENST00000392351(transcript)|ensembl:ENST00000539827(transcript)|ensembl:ENST00000542541(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006605"(protein targeting)|go:"GO:0007216"(G protein-coupled glutamate receptor signaling pathway)|go:"GO:0014069"(postsynaptic density)|go:"GO:0030425"(dendrite)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0035256"(G protein-coupled glutamate receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|go:"GO:2001256"(regulation of store-operated calcium entry)|interpro:IPR000697(EVH1)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR044100|mint:Q9NSC5|rcsb pdb:2P8V|rcsb pdb:3CVF|reactome:R-HSA-6794361|entrezgene/locuslink:9454(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:urVLzQFKnYT1bYOs3yRd9dd7lMk559292	rogid:U1y/y52nnf7zQUCNQlqk7JDgXi49606	intact-crc:5CBD2BE47DAC9560|rigid:PoE+zlZR11lNp7vEcRbZ8w/iRpo	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P39682	uniprotkb:Q9P2A4	intact:EBI-612|uniprotkb:D6VZC9|uniprotkb:E9P8Z1|ensemblfungi:YML046W	intact:EBI-742038|uniprotkb:C9IZN8|ensembl:ENSP00000225941|uniprotkb:Q9H0P6	psi-mi:prp39_yeast(display_long)|uniprotkb:YM9827.06(orf name)|uniprotkb:YML046W(locus name)|uniprotkb:PRP39(gene name)|psi-mi:PRP39(display_short)	psi-mi:abi3_human(display_long)|uniprotkb:New molecule including SH3(gene name synonym)|uniprotkb:ABI3(gene name)|psi-mi:ABI3(display_short)|uniprotkb:NESH(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11530034|imex:IM-24995-805	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013667.1|sgd:S000004509|dip:DIP-812N|mint:P39682|ensemblfungi:YML046W(gene)|ensemblfungi:YML046W_mRNA(transcript)|go:"GO:0000243"(commitment complex)|go:"GO:0000395"(mRNA 5'-splice site recognition)|go:"GO:0005685"(U1 snRNP)|go:"GO:0071004"(U2-type prespliceosome)|interpro:IPR003107(RNA-processing protein, HAT helix)|interpro:IPR011990(Tetratricopeptide-like helical)|rcsb pdb:5ZWN|rcsb pdb:6G90|rcsb pdb:6N7P|rcsb pdb:6N7R|rcsb pdb:6N7X|sgd:YML046W(identity)	refseq:NP_001128658.1|refseq:NP_057512.1|ensembl:ENSG00000108798(gene)|ensembl:ENST00000225941(transcript)|go:"GO:0002357"(defense response to tumor cell)|go:"GO:0005737"(cytoplasm)|go:"GO:0010593"(negative regulation of lamellipodium assembly)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031209"(SCAR complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0051015"(actin filament binding)|go:"GO:0061001"(regulation of dendritic spine morphogenesis)|go:"GO:0099151"(regulation of postsynaptic density assembly)|go:"GO:1900028"(negative regulation of ruffle assembly)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|go:"GO:2000249"(regulation of actin cytoskeleton reorganization)|go:"GO:2000774"(positive regulation of cellular senescence)|interpro:IPR001452(Src homology-3)|interpro:IPR012849(Abl-interactor, homeo-domain homologous region)|interpro:IPR028455|interpro:IPR028457|interpro:IPR036028|mint:Q9P2A4|entrezgene/locuslink:51225(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:urVLzQFKnYT1bYOs3yRd9dd7lMk559292	rogid:VAjz40ulLa5L+GmfL7ia5wTDND49606	intact-crc:E09AD182ACA82916|rigid:UCLOxnRR+nFmXuBy6ddfW7m0mDc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P39682	uniprotkb:P31249	intact:EBI-612|uniprotkb:D6VZC9|uniprotkb:E9P8Z1|ensemblfungi:YML046W	intact:EBI-3957655|ensembl:ENSP00000249440|ensembl:ENSP00000386498|ensembl:ENSP00000507129|uniprotkb:Q99955|uniprotkb:Q9BSC5	psi-mi:prp39_yeast(display_long)|uniprotkb:YM9827.06(orf name)|uniprotkb:YML046W(locus name)|uniprotkb:PRP39(gene name)|psi-mi:PRP39(display_short)	psi-mi:hxd3_human(display_long)|uniprotkb:HOXD3(gene name)|psi-mi:HOXD3(display_short)|uniprotkb:HOX1D(gene name synonym)|uniprotkb:HOX4A(gene name synonym)|uniprotkb:Homeobox protein Hox-4A(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11530005|imex:IM-24995-802	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013667.1|sgd:S000004509|dip:DIP-812N|mint:P39682|ensemblfungi:YML046W(gene)|ensemblfungi:YML046W_mRNA(transcript)|go:"GO:0000243"(commitment complex)|go:"GO:0000395"(mRNA 5'-splice site recognition)|go:"GO:0005685"(U1 snRNP)|go:"GO:0071004"(U2-type prespliceosome)|interpro:IPR003107(RNA-processing protein, HAT helix)|interpro:IPR011990(Tetratricopeptide-like helical)|rcsb pdb:5ZWN|rcsb pdb:6G90|rcsb pdb:6N7P|rcsb pdb:6N7R|rcsb pdb:6N7X|sgd:YML046W(identity)	ensembl:ENSG00000128652(gene)|ensembl:ENST00000249440(transcript)|ensembl:ENST00000410016(transcript)|ensembl:ENST00000683222(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016235"(aggresome)|go:"GO:0016604"(nuclear body)|go:"GO:0030878"(thyroid gland development)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0051216"(cartilage development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001827(Homeobox protein, antennapedia type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR025281|reactome:R-HSA-5617472|refseq:XP_011509367.1|refseq:XP_011509368.1|refseq:NP_008829.3|refseq:XP_005246566.1|refseq:XP_005246567.1|refseq:XP_005246568.1|refseq:XP_005246570.1|refseq:XP_006712540.1|entrezgene/locuslink:3232(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:urVLzQFKnYT1bYOs3yRd9dd7lMk559292	rogid:6egSlcCWXDnEWbOnwNGI/0ZxBM49606	intact-crc:D52F73BB9492B7D4|rigid:lHvJJ2aYGlXmwZMSAt4SgWVhhbU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P39682	uniprotkb:Q9Y2W2	intact:EBI-612|uniprotkb:D6VZC9|uniprotkb:E9P8Z1|ensemblfungi:YML046W	intact:EBI-714455|ensembl:ENSP00000261167|uniprotkb:Q96AY8	psi-mi:prp39_yeast(display_long)|uniprotkb:YM9827.06(orf name)|uniprotkb:YML046W(locus name)|uniprotkb:PRP39(gene name)|psi-mi:PRP39(display_short)	psi-mi:wbp11_human(display_long)|uniprotkb:SH3 domain-binding protein SNP70(gene name synonym)|uniprotkb:Npw38-binding protein(gene name synonym)|uniprotkb:WBP11(gene name)|psi-mi:WBP11(display_short)|uniprotkb:NPWBP(gene name synonym)|uniprotkb:SNP70(gene name synonym)|uniprotkb:SIPP1(gene name synonym)|uniprotkb:Splicing factor that interacts with PQBP-1 and PP1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11530074|imex:IM-24995-809	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013667.1|sgd:S000004509|dip:DIP-812N|mint:P39682|ensemblfungi:YML046W(gene)|ensemblfungi:YML046W_mRNA(transcript)|go:"GO:0000243"(commitment complex)|go:"GO:0000395"(mRNA 5'-splice site recognition)|go:"GO:0005685"(U1 snRNP)|go:"GO:0071004"(U2-type prespliceosome)|interpro:IPR003107(RNA-processing protein, HAT helix)|interpro:IPR011990(Tetratricopeptide-like helical)|rcsb pdb:5ZWN|rcsb pdb:6G90|rcsb pdb:6N7P|rcsb pdb:6N7R|rcsb pdb:6N7X|sgd:YML046W(identity)	rcsb pdb:7ABG|reactome:R-HSA-72163|ensembl:ENSG00000084463(gene)|ensembl:ENST00000261167(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045292"(mRNA cis splicing, via spliceosome)|go:"GO:0050699"(WW domain binding)|interpro:IPR019007|mint:Q9Y2W2|rcsb pdb:7ABF|refseq:NP_057396.1|entrezgene/locuslink:51729(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:urVLzQFKnYT1bYOs3yRd9dd7lMk559292	rogid:qE03bpSsQiJouJbn6ISt8DnD/pA9606	intact-crc:E41FB2EE1A1A03AF|rigid:oltImCl3zp8ZWC8W1/c6MUH6kTI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UHX1-6	uniprotkb:P39682	intact:EBI-11085298|ensembl:ENSP00000431960	intact:EBI-612|uniprotkb:D6VZC9|uniprotkb:E9P8Z1|ensemblfungi:YML046W	psi-mi:q9uhx1-6(display_long)|uniprotkb:PUF60(gene name)|psi-mi:PUF60(display_short)|uniprotkb:"60 kDa poly(U)-binding-splicing factor"(gene name synonym)|uniprotkb:FIR(gene name synonym)|uniprotkb:FUSE-binding protein-interacting repressor(gene name synonym)|uniprotkb:ROBPI(gene name synonym)|uniprotkb:Ro-binding protein 1(gene name synonym)|uniprotkb:SIAHBP1(gene name synonym)|uniprotkb:Siah-binding protein 1(gene name synonym)	psi-mi:prp39_yeast(display_long)|uniprotkb:YM9827.06(orf name)|uniprotkb:YML046W(locus name)|uniprotkb:PRP39(gene name)|psi-mi:PRP39(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11530063|imex:IM-24995-808	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000179950(gene)|ensembl:ENST00000527197(transcript)|intact:EBI-1053259(isoform-parent)|uniprotkb:Q9UHX1-6(isoform-parent)|entrezgene/locuslink:22827(identity)	refseq:NP_013667.1|sgd:S000004509|dip:DIP-812N|mint:P39682|ensemblfungi:YML046W(gene)|ensemblfungi:YML046W_mRNA(transcript)|go:"GO:0000243"(commitment complex)|go:"GO:0000395"(mRNA 5'-splice site recognition)|go:"GO:0005685"(U1 snRNP)|go:"GO:0071004"(U2-type prespliceosome)|interpro:IPR003107(RNA-processing protein, HAT helix)|interpro:IPR011990(Tetratricopeptide-like helical)|rcsb pdb:5ZWN|rcsb pdb:6G90|rcsb pdb:6N7P|rcsb pdb:6N7R|rcsb pdb:6N7X|sgd:YML046W(identity)	-	isoform-comment:"Contains a glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) at position 14."	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:rSsTImwmpEAWMCxLzF5Y4zVdeFM9606	rogid:urVLzQFKnYT1bYOs3yRd9dd7lMk559292	intact-crc:520EE84DF603DDD1|rigid:h06io8tHQ7CJ44GBbEpCK/JxMjc	false	sufficient binding region:15-513	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UHX1-5	uniprotkb:P39682	intact:EBI-11526420|ensembl:ENSP00000395417|ensembl:ENSP00000478209	intact:EBI-612|uniprotkb:D6VZC9|uniprotkb:E9P8Z1|ensemblfungi:YML046W	psi-mi:q9uhx1-5(display_long)|uniprotkb:PUF60(gene name)|psi-mi:PUF60(display_short)|uniprotkb:"60 kDa poly(U)-binding-splicing factor"(gene name synonym)|uniprotkb:FIR(gene name synonym)|uniprotkb:FUSE-binding protein-interacting repressor(gene name synonym)|uniprotkb:ROBPI(gene name synonym)|uniprotkb:Ro-binding protein 1(gene name synonym)|uniprotkb:SIAHBP1(gene name synonym)|uniprotkb:Siah-binding protein 1(gene name synonym)	psi-mi:prp39_yeast(display_long)|uniprotkb:YM9827.06(orf name)|uniprotkb:YML046W(locus name)|uniprotkb:PRP39(gene name)|psi-mi:PRP39(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11530052|imex:IM-24995-807	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-1053259(isoform-parent)|ensembl:ENSG00000179950(gene)|ensembl:ENSG00000274081(gene)|ensembl:ENST00000456095(transcript)|ensembl:ENST00000620953(transcript)|entrezgene/locuslink:22827(identity)	refseq:NP_013667.1|sgd:S000004509|dip:DIP-812N|mint:P39682|ensemblfungi:YML046W(gene)|ensemblfungi:YML046W_mRNA(transcript)|go:"GO:0000243"(commitment complex)|go:"GO:0000395"(mRNA 5'-splice site recognition)|go:"GO:0005685"(U1 snRNP)|go:"GO:0071004"(U2-type prespliceosome)|interpro:IPR003107(RNA-processing protein, HAT helix)|interpro:IPR011990(Tetratricopeptide-like helical)|rcsb pdb:5ZWN|rcsb pdb:6G90|rcsb pdb:6N7P|rcsb pdb:6N7R|rcsb pdb:6N7X|sgd:YML046W(identity)	-	isoform-comment:"Contains a glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) at position 14."	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:PSbIU++DIL6ysF0ccd3ZHzeJ5rs9606	rogid:urVLzQFKnYT1bYOs3yRd9dd7lMk559292	intact-crc:C100C048221CF31E|rigid:Spa7EzJSdtfwuHn1cV5zMiXBmgs	false	sufficient binding region:15-530	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UHX1-2	uniprotkb:P39682	intact:EBI-11529177|ensembl:ENSP00000322036|ensembl:ENSP00000478495	intact:EBI-612|uniprotkb:D6VZC9|uniprotkb:E9P8Z1|ensemblfungi:YML046W	psi-mi:q9uhx1-2(display_long)|uniprotkb:PUF60(gene name)|psi-mi:PUF60(display_short)|uniprotkb:"60 kDa poly(U)-binding-splicing factor"(gene name synonym)|uniprotkb:FIR(gene name synonym)|uniprotkb:FUSE-binding protein-interacting repressor(gene name synonym)|uniprotkb:ROBPI(gene name synonym)|uniprotkb:Ro-binding protein 1(gene name synonym)|uniprotkb:SIAHBP1(gene name synonym)|uniprotkb:Siah-binding protein 1(gene name synonym)	psi-mi:prp39_yeast(display_long)|uniprotkb:YM9827.06(orf name)|uniprotkb:YML046W(locus name)|uniprotkb:PRP39(gene name)|psi-mi:PRP39(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11530043|imex:IM-24995-806	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-1053259(isoform-parent)|ensembl:ENSG00000179950(gene)|ensembl:ENSG00000274081(gene)|ensembl:ENST00000349157(transcript)|ensembl:ENST00000612237(transcript)|uniprotkb:Q9UHX1-2(isoform-parent)|entrezgene/locuslink:22827(identity)	refseq:NP_013667.1|sgd:S000004509|dip:DIP-812N|mint:P39682|ensemblfungi:YML046W(gene)|ensemblfungi:YML046W_mRNA(transcript)|go:"GO:0000243"(commitment complex)|go:"GO:0000395"(mRNA 5'-splice site recognition)|go:"GO:0005685"(U1 snRNP)|go:"GO:0071004"(U2-type prespliceosome)|interpro:IPR003107(RNA-processing protein, HAT helix)|interpro:IPR011990(Tetratricopeptide-like helical)|rcsb pdb:5ZWN|rcsb pdb:6G90|rcsb pdb:6N7P|rcsb pdb:6N7R|rcsb pdb:6N7X|sgd:YML046W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:snVN9Lw5+MP2/aiq4z08ANwvr209606	rogid:urVLzQFKnYT1bYOs3yRd9dd7lMk559292	intact-crc:2A013D58FF00CA7F|rigid:C3+tQHyQVRHPL3u5/4qmzT1w/iw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P39724	uniprotkb:Q15654	intact:EBI-2343154|uniprotkb:D6VPH0|ensemblfungi:YAL046C	intact:EBI-742327|uniprotkb:O15170|uniprotkb:O15275|uniprotkb:Q9BTB2|uniprotkb:Q9BUE5|uniprotkb:Q9BXP3|uniprotkb:Q9UNT4|uniprotkb:A4D2E7|ensembl:ENSP00000200457|uniprotkb:F2ZC07|uniprotkb:F2ZC08	psi-mi:bol3_yeast(display_long)|uniprotkb:BOL3(gene name)|psi-mi:BOL3(display_short)|uniprotkb:AIM1(gene name synonym)|uniprotkb:Altered inheritance of mitochondria protein 1(gene name synonym)|uniprotkb:YAL046C(locus name)	psi-mi:trip6_human(display_long)|uniprotkb:TRIP6(gene name)|psi-mi:TRIP6(display_short)|uniprotkb:OIP1(gene name synonym)|uniprotkb:Opa-interacting protein 1(gene name synonym)|uniprotkb:Zyxin-related protein 1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11530110|imex:IM-24995-813	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009353.1|sgd:S000000044|interpro:IPR002634(BolA-like protein)|interpro:IPR036065|mint:P39724|ensemblfungi:YAL046C(gene)|ensemblfungi:YAL046C_mRNA(transcript)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0106035"(protein maturation by [4Fe-4S] cluster transfer)|sgd:YAL046C(identity)	refseq:NP_003293.2|ensembl:ENSP00000200457|ensembl:ENST00000417475|ensembl:ENSP00000413817|ensembl:ENST00000437505|ensembl:ENSP00000410736|ensembl:ENST00000619988|ensembl:ENSP00000479865|ensembl:ENSG00000087077(gene)|ensembl:ENST00000200457(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003723"(RNA binding)|go:"GO:0005149"(interleukin-1 receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0019900"(kinase binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0043009"(chordate embryonic development)|go:"GO:0046872"(metal ion binding)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|interpro:IPR001781(Zinc finger, LIM-type)|mint:Q15654|rcsb pdb:1X61|rcsb pdb:2DLO|dip:DIP-34466N|entrezgene/locuslink:7205(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:MLrW6Iu4YKXf87O1cyx5bY03VdE559292	rogid:9Okf3b6sMMwX5awAx991GN9iSsQ9606	intact-crc:A468CF69BCE63FAB|rigid:DQ5th5VfoAYEXx1mb5UxyiScCQI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q15437	uniprotkb:P39724	intact:EBI-742673|uniprotkb:Q5W183|uniprotkb:Q9BS15|uniprotkb:Q9BSI2|uniprotkb:Q9H1D7|intact:EBI-1048165|uniprotkb:Q503A9|uniprotkb:D3DW33|ensembl:ENSP00000262544|ensembl:ENSP00000338844|ensembl:ENSP00000366685|ensembl:ENSP00000497473	intact:EBI-2343154|uniprotkb:D6VPH0|ensemblfungi:YAL046C	psi-mi:sc23b_human(display_long)|uniprotkb:SEC23-related protein B(gene name synonym)|uniprotkb:SEC23B(gene name)|psi-mi:SEC23B(display_short)	psi-mi:bol3_yeast(display_long)|uniprotkb:BOL3(gene name)|psi-mi:BOL3(display_short)|uniprotkb:AIM1(gene name synonym)|uniprotkb:Altered inheritance of mitochondria protein 1(gene name synonym)|uniprotkb:YAL046C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11530101|imex:IM-24995-812	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001166216.1|refseq:NP_006354.2|refseq:NP_116780.1|refseq:NP_116781.1|ensembl:ENSG00000101310(gene)|ensembl:ENST00000262544(transcript)|ensembl:ENST00000336714(transcript)|ensembl:ENST00000377465(transcript)|ensembl:ENST00000650089(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008270"(zinc ion binding)|go:"GO:0012505"(endomembrane system)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0090110"(COPII-coated vesicle cargo loading)|go:"GO:0070971"(endoplasmic reticulum exit site)|interpro:IPR006895(Zinc finger, Sec23/Sec24-type)|interpro:IPR006896(Sec23/Sec24 trunk region)|interpro:IPR006900(Sec23/Sec24 helical region)|interpro:IPR007123(Gelsolin region)|interpro:IPR012990(Sec23/Sec24 beta-sandwich)|interpro:IPR029006|interpro:IPR036174|interpro:IPR036175|interpro:IPR036180|interpro:IPR036465|interpro:IPR037364|interpro:IPR037550|mint:Q15437|refseq:XP_016883082.1|entrezgene/locuslink:10483(identity)	refseq:NP_009353.1|sgd:S000000044|interpro:IPR002634(BolA-like protein)|interpro:IPR036065|mint:P39724|ensemblfungi:YAL046C(gene)|ensemblfungi:YAL046C_mRNA(transcript)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0106035"(protein maturation by [4Fe-4S] cluster transfer)|sgd:YAL046C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:+3KZ/1jjziSgJRcr81Axquofkl49606	rogid:MLrW6Iu4YKXf87O1cyx5bY03VdE559292	intact-crc:6194733A8CCA84B0|rigid:8MkNnnAeJJBcyFBfag9U5MtleHo	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P39724	uniprotkb:Q13422-7	intact:EBI-2343154|uniprotkb:D6VPH0|ensemblfungi:YAL046C	intact:EBI-11522367|ensembl:ENSP00000352123|ensembl:ENSP00000413025	psi-mi:bol3_yeast(display_long)|uniprotkb:BOL3(gene name)|psi-mi:BOL3(display_short)|uniprotkb:AIM1(gene name synonym)|uniprotkb:Altered inheritance of mitochondria protein 1(gene name synonym)|uniprotkb:YAL046C(locus name)	psi-mi:q13422-7(display_long)|uniprotkb:IKZF1(gene name)|psi-mi:IKZF1(display_short)|uniprotkb:IK1(gene name synonym)|uniprotkb:IKAROS(gene name synonym)|uniprotkb:Ikaros family zinc finger protein 1(gene name synonym)|uniprotkb:LYF1(gene name synonym)|uniprotkb:Lymphoid transcription factor LyF-1(gene name synonym)|uniprotkb:ZNFN1A1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11530092|imex:IM-24995-811	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009353.1|sgd:S000000044|interpro:IPR002634(BolA-like protein)|interpro:IPR036065|mint:P39724|ensemblfungi:YAL046C(gene)|ensemblfungi:YAL046C_mRNA(transcript)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0106035"(protein maturation by [4Fe-4S] cluster transfer)|sgd:YAL046C(identity)	intact:EBI-745305(isoform-parent)|ensembl:ENSG00000185811(gene)|ensembl:ENST00000359197(transcript)|ensembl:ENST00000439701(transcript)|uniprotkb:Q13422-7(isoform-parent)|entrezgene/locuslink:10320(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:MLrW6Iu4YKXf87O1cyx5bY03VdE559292	rogid:ou/ovXYoMneBNVp4pj38VxenfyY9606	intact-crc:CCCE4E96D5E33342|rigid:lFaKlyvgqMNhBmdwnTwouFOxKOM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O76003	uniprotkb:P39724	intact:EBI-374781|uniprotkb:Q96CE0|uniprotkb:Q9P1B0|uniprotkb:Q9P1B1|uniprotkb:B3KMP7|uniprotkb:B3KMQ5|uniprotkb:Q5JV01|ensembl:ENSP00000330836|ensembl:ENSP00000357633|ensembl:ENSP00000435445|uniprotkb:D3DRG2	intact:EBI-2343154|uniprotkb:D6VPH0|ensemblfungi:YAL046C	psi-mi:glrx3_human(display_long)|uniprotkb:GLRX3(gene name)|psi-mi:GLRX3(display_short)|uniprotkb:Thioredoxin-like protein 2(gene name synonym)|uniprotkb:PKC-interacting cousin of thioredoxin(gene name synonym)|uniprotkb:PKC-theta-interacting protein(gene name synonym)|uniprotkb:PICOT(gene name synonym)|uniprotkb:HUSSY-22(orf name)|uniprotkb:TXNL2(gene name synonym)	psi-mi:bol3_yeast(display_long)|uniprotkb:BOL3(gene name)|psi-mi:BOL3(display_short)|uniprotkb:AIM1(gene name synonym)|uniprotkb:Altered inheritance of mitochondria protein 1(gene name synonym)|uniprotkb:YAL046C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11530083|imex:IM-24995-810	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000108010(gene)|ensembl:ENST00000331244(transcript)|ensembl:ENST00000368644(transcript)|ensembl:ENST00000481034(transcript)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0003723"(RNA binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0030018"(Z disc)|go:"GO:0030425"(dendrite)|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051536"(iron-sulfur cluster binding)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|go:"GO:0097573"(glutathione oxidoreductase activity)|interpro:IPR002109(Glutaredoxin)|interpro:IPR004480(Glutaredoxin-related protein)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR033658|interpro:IPR036249|mint:O76003|rcsb pdb:2DIY|rcsb pdb:2WZ9|rcsb pdb:2YAN|rcsb pdb:3ZYW|reactome:R-HSA-917937|refseq:NP_001186797.1|refseq:NP_006532.2|dip:DIP-31306N|entrezgene/locuslink:10539(identity)	refseq:NP_009353.1|sgd:S000000044|interpro:IPR002634(BolA-like protein)|interpro:IPR036065|mint:P39724|ensemblfungi:YAL046C(gene)|ensemblfungi:YAL046C_mRNA(transcript)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0106035"(protein maturation by [4Fe-4S] cluster transfer)|sgd:YAL046C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:iKUSt6zbNzzXSKvW+vXMq3hKsEM9606	rogid:MLrW6Iu4YKXf87O1cyx5bY03VdE559292	intact-crc:7A0CBA734E787CA4|rigid:65CXs8AEkDwCIAvSRuAP0q6t2ck	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q14566	uniprotkb:P39946	intact:EBI-374900|uniprotkb:Q13504|uniprotkb:Q99859|uniprotkb:B2R6H2|ensembl:ENSP00000264156	intact:EBI-12838|uniprotkb:D6W2W9|ensemblfungi:YOR269W	psi-mi:mcm6_human(display_long)|uniprotkb:MCM6(gene name)|psi-mi:MCM6(display_short)|uniprotkb:p105MCM(gene name synonym)	psi-mi:lis1_yeast(display_long)|uniprotkb:PAC1(gene name)|psi-mi:PAC1(display_short)|uniprotkb:nudF homolog(gene name synonym)|uniprotkb:LIS1(gene name synonym)|uniprotkb:Lissencephaly-1 homolog(gene name synonym)|uniprotkb:YOR269W(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11530157|imex:IM-24995-818	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000264156(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0042555"(MCM complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902969"(mitotic DNA replication)|ensembl:ENSG00000076003(gene)|reactome:R-HSA-68962|reactome:R-HSA-69052|interpro:IPR008049(MCM protein 6)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041024|interpro:IPR041562|interpro:IPR001208(MCM)|mint:Q14566|rcsb pdb:2KLQ|rcsb pdb:2LE8|rcsb pdb:6XTX|rcsb pdb:6XTY|reactome:R-HSA-176187|reactome:R-HSA-176974|reactome:R-HSA-68867|reactome:R-HSA-68949|refseq:NP_005906.2|dip:DIP-31727N|entrezgene/locuslink:4175(identity)	ensemblfungi:YOR269W(gene)|ensemblfungi:YOR269W_mRNA(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007097"(nuclear migration)|go:"GO:0030473"(nuclear migration along microtubule)|go:"GO:0031023"(microtubule organizing center organization)|go:"GO:0042802"(identical protein binding)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0051012"(microtubule sliding)|go:"GO:0051301"(cell division)|go:"GO:0070840"(dynein complex binding)|go:"GO:1903033"(positive regulation of microtubule plus-end binding)|go:"GO:2000574"(obsolete regulation of microtubule motor activity)|go:"GO:2000582"(obsolete positive regulation of microtubule motor activity, plus-end-directed)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR017252(Dynein regulator)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|interpro:IPR037190|rcsb pdb:5VH9|rcsb pdb:5VLJ|refseq:NP_014912.1|sgd:S000005795|mint:P39946|dip:DIP-1485N|sgd:YOR269W(identity)	-	-	crc64:E667E4BA7602FB3B	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:gVpEwgfSwwxvP2T2CvCzIukthY49606	rogid:tyU5fR5V8csklk2QqAQHt3Mmz7c559292	intact-crc:2463889D67BE9B5E|rigid:ph2S3f8CdLJnhy9N1oGHGPx3SBc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P39729	uniprotkb:Q9UKT9	intact:EBI-20651|uniprotkb:D6VPI1|ensemblfungi:YAL036C	intact:EBI-747204|uniprotkb:Q8WWQ9|uniprotkb:Q8WWR0|uniprotkb:Q8WWR1|uniprotkb:Q8WWR2|uniprotkb:Q8WWR3|uniprotkb:Q8N574|uniprotkb:B4DVV5|uniprotkb:Q69BL6|uniprotkb:Q69BL7|uniprotkb:Q69BL8|uniprotkb:Q69BL9|uniprotkb:Q69BM0|uniprotkb:Q69BM1|uniprotkb:Q69BM2|uniprotkb:Q69BM3|uniprotkb:Q69BM5|ensembl:ENSP00000344544	psi-mi:rbg1_yeast(display_long)|uniprotkb:GTP-binding protein RBG1(gene name synonym)|uniprotkb:YAL036C(locus name)|uniprotkb:RBG1(gene name)|psi-mi:RBG1(display_short)|uniprotkb:FUN11(gene name synonym)|uniprotkb:Genetically interacts with ribosomal genes protein 1(gene name synonym)	psi-mi:ikzf3_human(display_long)|uniprotkb:ZNFN1A3(gene name synonym)|uniprotkb:Ikaros family zinc finger protein 3(gene name synonym)|uniprotkb:IKZF3(gene name)|psi-mi:IKZF3(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11530148|imex:IM-24995-817	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009364.1|sgd:S000000034|ensemblfungi:YAL036C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005844"(polysome)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:1903833"(positive regulation of cellular response to amino acid starvation)|interpro:IPR004095(TGS)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006073(GTP1/OBG)|interpro:IPR006074(GTP1/OBG, conserved site)|interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|interpro:IPR012676(TGS-like)|interpro:IPR027417|interpro:IPR031167|interpro:IPR031662|rcsb pdb:4A9A|ensemblfungi:YAL036C(gene)|dip:DIP-1750N|mint:P39729|sgd:YAL036C(identity)	refseq:NP_001271443.1|refseq:NP_001271444.1|refseq:NP_036613.2|refseq:NP_899051.1|refseq:NP_899052.1|refseq:NP_899053.1|refseq:NP_899054.1|refseq:NP_899055.1|refseq:NP_001271445.1|refseq:NP_001244337.1|refseq:NP_001244338.1|refseq:NP_001244339.1|refseq:NP_001244340.1|refseq:NP_001244341.1|refseq:NP_001244342.1|refseq:NP_001244343.1|ensembl:ENSG00000161405(gene)|ensembl:ENST00000346872(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007498"(mesoderm development)|go:"GO:0009617"(response to bacterium)|go:"GO:0030888"(regulation of B cell proliferation)|go:"GO:0042113"(B cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045577"(regulation of B cell differentiation)|go:"GO:0045619"(regulation of lymphocyte differentiation)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|go:"GO:0046872"(metal ion binding)|dip:DIP-56975N|entrezgene/locuslink:22806(identity)	-	crc64:D25C6C732B462A6B	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:PYUgCeuX5pWutVTDI01InMby/OE559292	rogid:2Kp6LefSLfK5VIiE6DmQusFIfMY9606	intact-crc:1DC36F0E5E95329F|rigid:Sa2J/1L1/w2ba1KoabuxlTAyzQE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q08379	uniprotkb:P39729	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	intact:EBI-20651|uniprotkb:D6VPI1|ensemblfungi:YAL036C	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:rbg1_yeast(display_long)|uniprotkb:GTP-binding protein RBG1(gene name synonym)|uniprotkb:YAL036C(locus name)|uniprotkb:RBG1(gene name)|psi-mi:RBG1(display_short)|uniprotkb:FUN11(gene name synonym)|uniprotkb:Genetically interacts with ribosomal genes protein 1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11530137|imex:IM-24995-816	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N|entrezgene/locuslink:2801(identity)	refseq:NP_009364.1|sgd:S000000034|ensemblfungi:YAL036C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005844"(polysome)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:1903833"(positive regulation of cellular response to amino acid starvation)|interpro:IPR004095(TGS)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006073(GTP1/OBG)|interpro:IPR006074(GTP1/OBG, conserved site)|interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|interpro:IPR012676(TGS-like)|interpro:IPR027417|interpro:IPR031167|interpro:IPR031662|rcsb pdb:4A9A|ensemblfungi:YAL036C(gene)|dip:DIP-1750N|mint:P39729|sgd:YAL036C(identity)	-	-	crc64:D25C6C732B462A6B	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2017/05/26	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	rogid:PYUgCeuX5pWutVTDI01InMby/OE559292	intact-crc:31549E1B5DE90C64|rigid:NPLA9nGy9IG1IB+lxlh4nLZNLCU	false	sufficient binding region:383-1002	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8NHQ1	uniprotkb:P39724	intact:EBI-739624|ensembl:ENSP00000264982|ensembl:ENSP00000419231|uniprotkb:Q96B31|uniprotkb:Q9H2C3|uniprotkb:Q9H2Z1|uniprotkb:Q9H940|uniprotkb:D3DNE9|uniprotkb:B7Z5I8|uniprotkb:B7Z7E8|uniprotkb:F5GZX8	intact:EBI-2343154|uniprotkb:D6VPH0|ensemblfungi:YAL046C	psi-mi:cep70_human(display_long)|uniprotkb:CEP70(gene name)|psi-mi:CEP70(display_short)|uniprotkb:BITE(gene name synonym)|uniprotkb:p10-binding protein(gene name synonym)	psi-mi:bol3_yeast(display_long)|uniprotkb:BOL3(gene name)|psi-mi:BOL3(display_short)|uniprotkb:AIM1(gene name synonym)|uniprotkb:Altered inheritance of mitochondria protein 1(gene name synonym)|uniprotkb:YAL046C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11530128|imex:IM-24995-815	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114107(gene)|ensembl:ENST00000264982(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|interpro:IPR019734|interpro:IPR037692|mint:Q8NHQ1|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|ensembl:ENST00000484888(transcript)|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_077817.2|refseq:XP_016862764.1|refseq:NP_001275893.1|refseq:NP_001275894.1|refseq:NP_001275895.1|refseq:NP_001275896.1|refseq:NP_001307527.1|refseq:NP_001307529.1|entrezgene/locuslink:80321(identity)	refseq:NP_009353.1|sgd:S000000044|interpro:IPR002634(BolA-like protein)|interpro:IPR036065|mint:P39724|ensemblfungi:YAL046C(gene)|ensemblfungi:YAL046C_mRNA(transcript)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0106035"(protein maturation by [4Fe-4S] cluster transfer)|sgd:YAL046C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:S4yveQWcvdVtAUX65gqrJ5Dv0Mc9606	rogid:MLrW6Iu4YKXf87O1cyx5bY03VdE559292	intact-crc:F62DD01C0F4D2BA6|rigid:8wdt3l1cquQehSaPTrETtvhqtDw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8N9N5-2	uniprotkb:P39724	intact:EBI-11524452|ensembl:ENSP00000347125	intact:EBI-2343154|uniprotkb:D6VPH0|ensemblfungi:YAL046C	psi-mi:q8n9n5-2(display_long)|uniprotkb:BANP(gene name)|psi-mi:BANP(display_short)|uniprotkb:BEN domain-containing protein 1(gene name synonym)|uniprotkb:BEND1(gene name synonym)|uniprotkb:Btg3-associated nuclear protein(gene name synonym)|uniprotkb:SMAR1(gene name synonym)|uniprotkb:Scaffold/matrix-associated region-1-binding protein(gene name synonym)	psi-mi:bol3_yeast(display_long)|uniprotkb:BOL3(gene name)|psi-mi:BOL3(display_short)|uniprotkb:AIM1(gene name synonym)|uniprotkb:Altered inheritance of mitochondria protein 1(gene name synonym)|uniprotkb:YAL046C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11530119|imex:IM-24995-814	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000172530(gene)|ensembl:ENST00000355022(transcript)|intact:EBI-744695(isoform-parent)|uniprotkb:Q8N9N5-2(isoform-parent)|entrezgene/locuslink:54971(identity)	refseq:NP_009353.1|sgd:S000000044|interpro:IPR002634(BolA-like protein)|interpro:IPR036065|mint:P39724|ensemblfungi:YAL046C(gene)|ensemblfungi:YAL046C_mRNA(transcript)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0106035"(protein maturation by [4Fe-4S] cluster transfer)|sgd:YAL046C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:ESe6iCAhvq+i57fQHz3rGyg6UOo9606	rogid:MLrW6Iu4YKXf87O1cyx5bY03VdE559292	intact-crc:8152D1BF343821F5|rigid:ccEvLtoXDVwSCelr9mseh0wQBAY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P39961	uniprotkb:Q9H9H4	intact:EBI-22239|uniprotkb:D3DM93|ensemblfungi:YER184C	intact:EBI-4400866|intact:EBI-28975719|ensembl:ENSP00000267202	psi-mi:tog1_yeast(display_long)|uniprotkb:TOG1(gene name)|psi-mi:TOG1(display_short)|uniprotkb:Transcriptional regulator of oleate 1(gene name synonym)|uniprotkb:YER184C(locus name)	psi-mi:vp37b_human(display_long)|uniprotkb:VPS37B(gene name)|psi-mi:VPS37B(display_short)|uniprotkb:ESCRT-I complex subunit VPS37B(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11530195|imex:IM-24995-822	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011111.1|sgd:S000000986|dip:DIP-5488N|mint:P39961|ensemblfungi:YER184C(gene)|ensemblfungi:YER184C_mRNA(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR001138(Fungal transcriptional regulatory protein, N-terminal)|interpro:IPR007219(Fungal specific transcription factor)|interpro:IPR036864|sgd:YER184C(identity)	ensembl:ENSP00000267202|refseq:NP_078943.1|ensembl:ENSG00000139722(gene)|ensembl:ENST00000267202(transcript)|go:"GO:0000813"(ESCRT I complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0010008"(endosome membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0030496"(midbody)|go:"GO:0031902"(late endosome membrane)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1902188"(obsolete positive regulation of viral release from host cell)|go:"GO:1903774"(positive regulation of viral budding via host ESCRT complex)|interpro:IPR009851(Modifier of rudimentary, Modr)|interpro:IPR029012|interpro:IPR037202|mint:Q9H9H4|rcsb pdb:6VME|reactome:R-HSA-162588|reactome:R-HSA-174490|reactome:R-HSA-917729|reactome:R-HSA-9610379|reactome:R-HSA-9615710|entrezgene/locuslink:79720(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:5LvJUSL4Do4rBxPon6hQplqYXFU559292	rogid:dj398+zsegXf+gk9OiSeZAVlmqk9606	intact-crc:2674DE137CF3FBEB|rigid:T3u93KxnR1U6au4MV/V3opPIwjE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UJV3-2	uniprotkb:P39946	intact:EBI-10172526|ensembl:ENSP00000413976	intact:EBI-12838|uniprotkb:D6W2W9|ensemblfungi:YOR269W	psi-mi:q9ujv3-2(display_long)|uniprotkb:RING-type E3 ubiquitin transferase MID2(gene name synonym)|uniprotkb:FXY2(gene name synonym)|uniprotkb:Midin-2(gene name synonym)|uniprotkb:Midline defect 2(gene name synonym)|uniprotkb:Midline-2(gene name synonym)|uniprotkb:RING finger protein 60(gene name synonym)|uniprotkb:RNF60(gene name synonym)|uniprotkb:TRIM1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 1(gene name synonym)|uniprotkb:MID2(gene name)|psi-mi:MID2(display_short)	psi-mi:lis1_yeast(display_long)|uniprotkb:PAC1(gene name)|psi-mi:PAC1(display_short)|uniprotkb:nudF homolog(gene name synonym)|uniprotkb:LIS1(gene name synonym)|uniprotkb:Lissencephaly-1 homolog(gene name synonym)|uniprotkb:YOR269W(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11530184|imex:IM-24995-821	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-751983(isoform-parent)|uniprotkb:Q9UJV3-2(isoform-parent)|ensembl:ENSG00000080561(gene)|ensembl:ENST00000443968(transcript)|entrezgene/locuslink:11043(identity)	ensemblfungi:YOR269W(gene)|ensemblfungi:YOR269W_mRNA(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007097"(nuclear migration)|go:"GO:0030473"(nuclear migration along microtubule)|go:"GO:0031023"(microtubule organizing center organization)|go:"GO:0042802"(identical protein binding)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0051012"(microtubule sliding)|go:"GO:0051301"(cell division)|go:"GO:0070840"(dynein complex binding)|go:"GO:1903033"(positive regulation of microtubule plus-end binding)|go:"GO:2000574"(obsolete regulation of microtubule motor activity)|go:"GO:2000582"(obsolete positive regulation of microtubule motor activity, plus-end-directed)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR017252(Dynein regulator)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|interpro:IPR037190|rcsb pdb:5VH9|rcsb pdb:5VLJ|refseq:NP_014912.1|sgd:S000005795|mint:P39946|dip:DIP-1485N|sgd:YOR269W(identity)	-	-	crc64:E667E4BA7602FB3B	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:/FJ+V2H7SaWon7caUWkEkmHFVxQ9606	rogid:tyU5fR5V8csklk2QqAQHt3Mmz7c559292	intact-crc:473BAD39E8143DA3|rigid:ARbzysojGHvgGNGr1TPCQwd7Vfc	false	sufficient binding region:21-705	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P39946	uniprotkb:Q96HB5	intact:EBI-12838|uniprotkb:D6W2W9|ensemblfungi:YOR269W	intact:EBI-744556|uniprotkb:B4DTU2|ensembl:ENSP00000470294|ensembl:ENSP00000474761|ensembl:ENSP00000475676|uniprotkb:A8K5Q5|uniprotkb:B4DF24|uniprotkb:F5GZU4|uniprotkb:B4DFC1	psi-mi:lis1_yeast(display_long)|uniprotkb:PAC1(gene name)|psi-mi:PAC1(display_short)|uniprotkb:nudF homolog(gene name synonym)|uniprotkb:LIS1(gene name synonym)|uniprotkb:Lissencephaly-1 homolog(gene name synonym)|uniprotkb:YOR269W(locus name)	psi-mi:cc120_human(display_long)|uniprotkb:CCDC120(gene name)|psi-mi:CCDC120(display_short)|uniprotkb:JM11(orf name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11530175|imex:IM-24995-820	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YOR269W(gene)|ensemblfungi:YOR269W_mRNA(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007097"(nuclear migration)|go:"GO:0030473"(nuclear migration along microtubule)|go:"GO:0031023"(microtubule organizing center organization)|go:"GO:0042802"(identical protein binding)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0051012"(microtubule sliding)|go:"GO:0051301"(cell division)|go:"GO:0070840"(dynein complex binding)|go:"GO:1903033"(positive regulation of microtubule plus-end binding)|go:"GO:2000574"(obsolete regulation of microtubule motor activity)|go:"GO:2000582"(obsolete positive regulation of microtubule motor activity, plus-end-directed)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR017252(Dynein regulator)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|interpro:IPR037190|rcsb pdb:5VH9|rcsb pdb:5VLJ|refseq:NP_014912.1|sgd:S000005795|mint:P39946|dip:DIP-1485N|sgd:YOR269W(identity)	refseq:NP_001156795.1|refseq:NP_296375.1|go:"GO:0005814"(centriole)|go:"GO:0008104"(protein localization)|go:"GO:0030426"(growth cone)|go:"GO:0034454"(microtubule anchoring at centrosome)|go:"GO:0120103"(centriolar subdistal appendage)|interpro:IPR021774|interpro:IPR039108|interpro:IPR043447|ensembl:ENSG00000147144(gene)|ensembl:ENST00000496529(transcript)|ensembl:ENST00000597275(transcript)|ensembl:ENST00000606812(transcript)|go:"GO:0005768"(endosome)|refseq:NP_001258764.1|refseq:NP_001258765.1|refseq:NP_001156793.2|refseq:NP_001156794.1|entrezgene/locuslink:90060(identity)	-	crc64:E667E4BA7602FB3B	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:tyU5fR5V8csklk2QqAQHt3Mmz7c559292	rogid:uBgmQJDTqECaTKOU/uQQHkWB/Nc9606	intact-crc:4ECC0C450DFFD4B2|rigid:uN0faWdTYD57KDUYwnOtCHBY2BE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P39946	uniprotkb:Q5JR59-3	intact:EBI-12838|uniprotkb:D6W2W9|ensemblfungi:YOR269W	intact:EBI-11522433|ensembl:ENSP00000370186	psi-mi:lis1_yeast(display_long)|uniprotkb:PAC1(gene name)|psi-mi:PAC1(display_short)|uniprotkb:nudF homolog(gene name synonym)|uniprotkb:LIS1(gene name synonym)|uniprotkb:Lissencephaly-1 homolog(gene name synonym)|uniprotkb:YOR269W(locus name)	psi-mi:q5jr59-3(display_long)|uniprotkb:MTUS2(gene name)|psi-mi:MTUS2(display_short)|uniprotkb:CAZIP(gene name synonym)|uniprotkb:Cardiac zipper protein(gene name synonym)|uniprotkb:KIAA0774(gene name synonym)|uniprotkb:Microtubule plus-end tracking protein TIP150(gene name synonym)|uniprotkb:TIP150(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11530166|imex:IM-24995-819	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YOR269W(gene)|ensemblfungi:YOR269W_mRNA(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007097"(nuclear migration)|go:"GO:0030473"(nuclear migration along microtubule)|go:"GO:0031023"(microtubule organizing center organization)|go:"GO:0042802"(identical protein binding)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0051012"(microtubule sliding)|go:"GO:0051301"(cell division)|go:"GO:0070840"(dynein complex binding)|go:"GO:1903033"(positive regulation of microtubule plus-end binding)|go:"GO:2000574"(obsolete regulation of microtubule motor activity)|go:"GO:2000582"(obsolete positive regulation of microtubule motor activity, plus-end-directed)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR017252(Dynein regulator)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|interpro:IPR037190|rcsb pdb:5VH9|rcsb pdb:5VLJ|refseq:NP_014912.1|sgd:S000005795|mint:P39946|dip:DIP-1485N|sgd:YOR269W(identity)	ensembl:ENSG00000132938(gene)|ensembl:ENST00000380808(transcript)|intact:EBI-742948(isoform-parent)|uniprotkb:Q5JR59-3(isoform-parent)|entrezgene/locuslink:23281(identity)	-	crc64:E667E4BA7602FB3B	isoform-comment:No experimental confirmation available.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:tyU5fR5V8csklk2QqAQHt3Mmz7c559292	rogid:npId9tC7VoLN/jteoBiRbSYChPs9606	intact-crc:9395631389F90807|rigid:mcPqwa1Q/HPtG6yn9wOQcWws6DA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49910	uniprotkb:P39984	intact:EBI-741694|intact:EBI-28968591|ensembl:ENSP00000366542|ensembl:ENSP00000507525	intact:EBI-8185|uniprotkb:D3DLJ4|ensemblfungi:YEL056W	psi-mi:zn165_human(display_long)|uniprotkb:LD65(gene name synonym)|uniprotkb:Zinc finger and SCAN domain-containing protein 7(gene name synonym)|uniprotkb:Cancer/testis antigen 53(gene name synonym)|uniprotkb:ZNF165(gene name)|psi-mi:ZNF165(display_short)|uniprotkb:ZPF165(gene name synonym)|uniprotkb:ZSCAN7(gene name synonym)	psi-mi:hat2_yeast(display_long)|uniprotkb:HAT2(gene name)|psi-mi:HAT2(display_short)|uniprotkb:YEL056W(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11530222|imex:IM-24995-825	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003438.1|ensembl:ENSP00000366542|ensembl:ENSP00000507525|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR038269|mint:P49910|ensembl:ENSG00000197279(gene)|ensembl:ENST00000377325(transcript)|ensembl:ENST00000683778(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|refseq:XP_016866747.1|refseq:XP_016866748.1|refseq:XP_016866749.1|entrezgene/locuslink:7718(identity)	sgd:S000000782|refseq:NP_010858.3|mint:P39984|dip:DIP-2363N|ensemblfungi:YEL056W(gene)|ensemblfungi:YEL056W_mRNA(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006333"(chromatin assembly or disassembly)|go:"GO:0006348"|go:"GO:0016573"(histone acetylation)|go:"GO:0042393"(histone binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR022052|interpro:IPR036322|rcsb pdb:4PSW|rcsb pdb:4PSX|reactome:R-SCE-3214815|reactome:R-SCE-3214847|reactome:R-SCE-3214858|sgd:YEL056W(identity)	-	-	crc64:C27A91C99D9FCAB7	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:4BpNwyrtFulW7rWXuy+Y7cdgYps9606	rogid:WlhnJ6TT8FLgKn4ZtoJh0tWUBQk559292	intact-crc:5B4FECC7E8BD7142|rigid:0LRXkxK0Tebwqa2us2WlyR13F1Q	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P39976	uniprotkb:Q9Y6D9	intact:EBI-5933|uniprotkb:D3DLI0|ensemblfungi:YEL071W	intact:EBI-742610|uniprotkb:B3KR41|uniprotkb:Q9UNH0|uniprotkb:Q13312|uniprotkb:Q75MI0|uniprotkb:Q86UM4|ensembl:ENSP00000265854|ensembl:ENSP00000382562|ensembl:ENSP00000385334	psi-mi:dld3_yeast(display_long)|uniprotkb:YEL071W(locus name)|uniprotkb:DLD3(gene name)|psi-mi:DLD3(display_short)|uniprotkb:D-lactate ferricytochrome C oxidoreductase(gene name synonym)|uniprotkb:"(R)-2-hydroxyglutarate--pyruvate transhydrogenase"(gene name synonym)|uniprotkb:D-lactate dehydrogenase [cytochrome] 3(gene name synonym)	psi-mi:md1l1_human(display_long)|uniprotkb:Mitotic arrest deficient 1-like protein 1(gene name synonym)|uniprotkb:Mitotic checkpoint MAD1 protein homolog(gene name synonym)|uniprotkb:Tax-binding protein 181(gene name synonym)|uniprotkb:MAD1L1(gene name)|psi-mi:MAD1L1(display_short)|uniprotkb:MAD1(gene name synonym)|uniprotkb:TXBP181(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11530213|imex:IM-24995-824	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010843.1|sgd:S000000797|dip:DIP-6418N|mint:P39976|ensemblfungi:YEL071W(gene)|ensemblfungi:YEL071W_mRNA(transcript)|go:"GO:0004458"("D-lactate dehydrogenase (cytochrome) activity")|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0019249"(lactate biosynthetic process)|go:"GO:0030447"(filamentous growth)|go:"GO:0071949"(FAD binding)|go:"GO:0099615"("(D)-2-hydroxyglutarate-pyruvate transhydrogenase activity")|interpro:IPR004113(FAD-linked oxidase, C-terminal)|interpro:IPR006094(FAD linked oxidase, N-terminal)|interpro:IPR016164(FAD-linked oxidase-like, C-terminal)|interpro:IPR016166(FAD-binding, type 2)|interpro:IPR016167(FAD-binding, type 2, subdomain 1)|interpro:IPR016169(CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2)|interpro:IPR016171(Vanillyl-alcohol oxidase, C-terminal subdomain 2)|interpro:IPR036318|sgd:YEL071W(identity)	refseq:NP_001013858.1|refseq:NP_001013859.1|refseq:NP_003541.2|refseq:NP_001291452.1|refseq:NP_001291453.1|ensembl:ENSG00000002822(gene)|ensembl:ENST00000265854(transcript)|go:"GO:0090235"(regulation of metaphase plate congression)|go:"GO:1902426"(deactivation of mitotic spindle assembly checkpoint)|interpro:IPR008672(Mitotic checkpoint)|mint:Q9Y6D9|rcsb pdb:1GO4|rcsb pdb:4DZO|rcsb pdb:7B1F|rcsb pdb:7B1H|rcsb pdb:7B1J|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|ensembl:ENST00000399654(transcript)|ensembl:ENST00000406869(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043515"(kinetochore binding)|go:"GO:0044615"(nuclear pore nuclear basket)|go:"GO:0048538"(thymus development)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0072686"(mitotic spindle)|refseq:XP_005249934.1|dip:DIP-29654N|entrezgene/locuslink:8379(identity)	-	crc64:4809F74EDF07F520	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:f0zrUtFfKHDu2gUN7thcyPp/Z50559292	rogid:9CcqpZlN0IgqC939rIo7vNgOvLQ9606	intact-crc:701FD0E89441CD14|rigid:T24bmbHLm6aNwasOX9GG0Wfbgy0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P39962	uniprotkb:P50222	intact:EBI-4740|uniprotkb:D3DM29|ensemblfungi:YER123W	intact:EBI-748397|uniprotkb:O75263|ensembl:ENSP00000262041|uniprotkb:Q9UPL6|uniprotkb:B2R8I7|intact:EBI-10172134|intact:EBI-11522964|intact:EBI-11750003|intact:EBI-12702266|uniprotkb:A4D127	psi-mi:kc13_yeast(display_long)|uniprotkb:YCK3(gene name)|psi-mi:YCK3(display_short)|uniprotkb:CKI3(gene name synonym)|uniprotkb:YER123W(locus name)	psi-mi:meox2_human(display_long)|uniprotkb:Mesenchyme homeobox 2(gene name synonym)|uniprotkb:Growth arrest-specific homeobox(gene name synonym)|uniprotkb:MEOX2(gene name)|psi-mi:MEOX2(display_short)|uniprotkb:GAX(gene name synonym)|uniprotkb:MOX2(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11530204|imex:IM-24995-823	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011049.2|sgd:S000000925|dip:DIP-6331N|mint:P39962|ensemblfungi:YER123W(gene)|ensemblfungi:YER123W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006897"(endocytosis)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0031965"(nuclear membrane)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|sgd:YER123W(identity)	ensembl:ENSG00000106511(gene)|ensembl:ENST00000262041(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0001757"(somite specification)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007275"(multicellular organism development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008015"(blood circulation)|go:"GO:0016607"(nuclear speck)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060173"(limb development)|go:"GO:0061053"(somite development)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR042634|refseq:NP_005915.2|entrezgene/locuslink:4223(identity)	-	crc64:FD4BBA311D0CD805	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2017/05/26	rogid:RIRZO4asqxXqkm1L6tHZtWI/rQQ559292	rogid:fMv0ruKikzQ3MC0PBvJ3pOAjW+U9606	intact-crc:F01F8B166FE62E1B|rigid:cwsTXbnKusLLEFlzzX/sy7fgHR4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P39996	uniprotkb:Q8N6L0	intact:EBI-22308|uniprotkb:D3DLN3|ensemblfungi:YEL017W	intact:EBI-749265|uniprotkb:Q96MC3|ensembl:ENSP00000404220	psi-mi:gtt3_yeast(display_long)|uniprotkb:GTT3(gene name)|psi-mi:GTT3(display_short)|uniprotkb:YEL017W(locus name)	psi-mi:kash5_human(display_long)|uniprotkb:KASH5(gene name)|psi-mi:KASH5(display_short)|uniprotkb:CCDC155(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 155(gene name synonym)|uniprotkb:KASH domain-containing protein 5(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11530258|imex:IM-24995-829	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000000743|refseq:NP_010899.3|dip:DIP-2062N|mint:P39996|ensemblfungi:YEL017W(gene)|ensemblfungi:YEL017W_mRNA(transcript)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034399"(nuclear periphery)|interpro:IPR038872|sgd:YEL017W(identity)	refseq:NP_653289.3|ensembl:ENSG00000161609(gene)|ensembl:ENST00000447857(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034397"(telomere localization)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051225"(spindle assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0090172"(microtubule cytoskeleton organization involved in homologous chromosome segregation)|go:"GO:0090220"(chromosome localization to nuclear envelope involved in homologous chromosome segregation)|go:"GO:0090619"(meiotic spindle pole)|interpro:IPR011992(EF-Hand type)|interpro:IPR028168|interpro:IPR028170|interpro:IPR039508|mint:Q8N6L0|rcsb pdb:6R2I|rcsb pdb:6WMF|entrezgene/locuslink:147872(identity)	-	crc64:E9F07EFD2A522006	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:YxznRNPatBf8VkhVPwSCfB5pCDU559292	rogid:Wl9L7AcvDHCZuKjYLn8QgGIbZTc9606	intact-crc:8A40D4F7CD6C659F|rigid:ZOF8n/du+kl3uNplIoAReVMTnjI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8N6G5	uniprotkb:P39996	intact:EBI-10267100|uniprotkb:Q9P1I6|uniprotkb:Q6MZJ5|uniprotkb:B3KWL7|uniprotkb:Q8TCH4|uniprotkb:Q6MZP6|ensembl:ENSP00000363590	intact:EBI-22308|uniprotkb:D3DLN3|ensemblfungi:YEL017W	psi-mi:cgat2_human(display_long)|uniprotkb:CSGALNACT2(gene name)|psi-mi:CSGALNACT2(display_short)|uniprotkb:CHGN2(gene name synonym)|uniprotkb:Chondroitin beta-1,4-N-acetylgalactosaminyltransferase 2(gene name synonym)|uniprotkb:GALNACT2(gene name synonym)|uniprotkb:PRO0082(orf name)	psi-mi:gtt3_yeast(display_long)|uniprotkb:GTT3(gene name)|psi-mi:GTT3(display_short)|uniprotkb:YEL017W(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11530249|imex:IM-24995-828	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_061060.3|ensembl:ENSG00000169826(gene)|ensembl:ENST00000374466(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0008376"(acetylgalactosaminyltransferase activity)|go:"GO:0016020"(membrane)|go:"GO:0030166"(proteoglycan biosynthetic process)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0030206"(chondroitin sulfate biosynthetic process)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0047237"(glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity)|go:"GO:0047238"(glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity)|go:"GO:0050650"(chondroitin sulfate proteoglycan biosynthetic process)|go:"GO:0050651"(dermatan sulfate proteoglycan biosynthetic process)|go:"GO:0050652"(dermatan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process)|go:"GO:0050653"(chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process)|interpro:IPR008428(Chondroitin N-acetylgalactosaminyltransferase)|interpro:IPR029044|reactome:R-HSA-2022870|refseq:NP_001306583.1|refseq:NP_001306585.1|entrezgene/locuslink:55454(identity)	sgd:S000000743|refseq:NP_010899.3|dip:DIP-2062N|mint:P39996|ensemblfungi:YEL017W(gene)|ensemblfungi:YEL017W_mRNA(transcript)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034399"(nuclear periphery)|interpro:IPR038872|sgd:YEL017W(identity)	-	-	crc64:E9F07EFD2A522006	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:uK24H440Kn7+cnVc8C+3dV4SXw89606	rogid:YxznRNPatBf8VkhVPwSCfB5pCDU559292	intact-crc:36FDFDE8CF8B97D3|rigid:gWMsutxXJu4ebSSQXUfh46BadP0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q16637-3	uniprotkb:P39990	intact:EBI-395447|ensembl:ENSP00000424926|ensembl:ENSP00000486152|ensembl:ENSP00000487015|ensembl:ENSP00000487029|intact:EBI-8628183|intact:MINT-95595	intact:EBI-12032|ensemblfungi:YEL026W|uniprotkb:D3DLM2	psi-mi:q16637-3(display_long)|uniprotkb:Iso7-SMN(isoform synonym)|uniprotkb:SMN1(gene name)|psi-mi:SMN1(display_short)|uniprotkb:SMN2(gene name)|psi-mi:SMN2(display_short)|uniprotkb:SMN(gene name synonym)|uniprotkb:SMNT(gene name synonym)|uniprotkb:SMNC(gene name synonym)|uniprotkb:Component of gems 1(gene name synonym)|uniprotkb:Gemin-1(gene name synonym)	psi-mi:snu13_yeast(display_long)|uniprotkb:YEL026W(locus name)|uniprotkb:SNU13(gene name)|psi-mi:SNU13(display_short)|uniprotkb:Small nuclear ribonucleoprotein-associated protein 1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11530240|imex:IM-24995-827	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-395421(smn_human)|ensembl:ENSG00000275349(gene)|ensembl:ENST00000506163(transcript)|ensembl:ENST00000626847(transcript)|ensembl:ENST00000628353(transcript)|ensembl:ENST00000628642(transcript)|ensembl:ENSG00000172062(gene)|ensembl:ENSG00000205571(gene)|ensembl:ENSG00000273772(gene)|uniprotkb:Q16637-3(isoform-parent)|entrezgene/locuslink:6607(identity)	ensemblfungi:YEL026W(gene)|ensemblfungi:YEL026W_mRNA(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0030490"(maturation of SSU-rRNA)|go:"GO:0030621"(U4 snRNA binding)|go:"GO:0031428"(box C/D RNP complex)|go:"GO:0032040"(small-subunit processome)|go:"GO:0034511"(U3 snoRNA binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:1905216"(positive regulation of RNA binding)|interpro:IPR002415(High mobility group-like nuclear protein)|interpro:IPR004037(Ribosomal protein L7Ae)|interpro:IPR004038(Ribosomal protein L7Ae/L30e/S12e/Gadd45)|interpro:IPR018492|interpro:IPR029064|rcsb pdb:1ZWZ|rcsb pdb:2ALE|rcsb pdb:3JCM|go:"GO:0005654"(nucleoplasm)|rcsb pdb:5GAN|rcsb pdb:5GAP|rcsb pdb:5NRL|rcsb pdb:5TZS|rcsb pdb:5WLC|rcsb pdb:5WYJ|rcsb pdb:5WYK|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:6KE6|rcsb pdb:6LQP|rcsb pdb:6LQQ|rcsb pdb:6LQR|rcsb pdb:6LQS|rcsb pdb:6LQT|rcsb pdb:6LQU|rcsb pdb:6LQV|rcsb pdb:6ND4|rcsb pdb:6ZQA|rcsb pdb:6ZQB|rcsb pdb:6ZQC|rcsb pdb:6ZQD|rcsb pdb:6ZQE|rcsb pdb:7AJT|rcsb pdb:7AJU|rcsb pdb:4NUT|reactome:R-SCE-6791226|refseq:NP_010888.1|sgd:S000000752|mint:P39990|dip:DIP-2870N|sgd:YEL026W(identity)	-	isoform-comment:Thought to be a non-functional protein that lacks the capacity to oligomerize and thus cannot interact with Sm proteins. Primarily derived from SMN2 gene.	crc64:4489780153E8F182	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:ICA63eidVxJ219M+YZJ20zNh+xU9606	rogid:4C07wkvZ4Nts4Oxw4/L7QMkwcmE559292	intact-crc:47DACDB7EA5619F1|rigid:gHrDiO7IspHzzgYrGnScU0x9cyM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q16637	uniprotkb:P39990	intact:EBI-395421|uniprotkb:Q13119|uniprotkb:Q549U5|uniprotkb:Q96J51|ensembl:ENSP00000305857|uniprotkb:A8K0V4|ensembl:ENSP00000370083|ensembl:ENSP00000370117|ensembl:ENSP00000370119|ensembl:ENSP00000479920|ensembl:ENSP00000482966|ensembl:ENSP00000483515|ensembl:ENSP00000483819|ensembl:ENSP00000487206|ensembl:ENSP00000487421	intact:EBI-12032|ensemblfungi:YEL026W|uniprotkb:D3DLM2	psi-mi:smn_human(display_long)|uniprotkb:SMN1(gene name)|psi-mi:SMN1(display_short)|uniprotkb:SMN(gene name synonym)|uniprotkb:SMNT(gene name synonym)|uniprotkb:SMN2(gene name)|psi-mi:SMN2(display_short)|uniprotkb:SMNC(gene name synonym)|uniprotkb:Component of gems 1(gene name synonym)|uniprotkb:Gemin-1(gene name synonym)	psi-mi:snu13_yeast(display_long)|uniprotkb:YEL026W(locus name)|uniprotkb:SNU13(gene name)|psi-mi:SNU13(display_short)|uniprotkb:Small nuclear ribonucleoprotein-associated protein 1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11530231|imex:IM-24995-826	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000335.1|refseq:NP_059107.1|refseq:NP_075012.1|refseq:NP_075013.1|refseq:NP_075014.1|refseq:NP_075015.1|ensembl:ENSG00000172062(gene)|ensembl:ENSG00000205571(gene)|ensembl:ENSG00000273772(gene)|ensembl:ENSG00000275349(gene)|ensembl:ENSG00000277773(gene)|ensembl:ENST00000351205(transcript)|ensembl:ENST00000380707(transcript)|ensembl:ENST00000380741(transcript)|ensembl:ENST00000380743(transcript)|ensembl:ENST00000614610(transcript)|ensembl:ENST00000618251(transcript)|ensembl:ENST00000618661(transcript)|ensembl:ENST00000622739(transcript)|ensembl:ENST00000627341(transcript)|ensembl:ENST00000629122(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0007399"(nervous system development)|go:"GO:0015030"(Cajal body)|go:"GO:0016604"(nuclear body)|go:"GO:0030018"(Z disc)|go:"GO:0030424"(axon)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043204"(perikaryon)|go:"GO:0097504"(Gemini of coiled bodies)|interpro:IPR002999(Tudor)|interpro:IPR010304(Survival motor neuron)|mint:Q16637|rcsb pdb:1G5V|rcsb pdb:1MHN|rcsb pdb:2LEH|rcsb pdb:4A4E|rcsb pdb:4A4G|rcsb pdb:4GLI|rcsb pdb:4QQ6|rcsb pdb:5XJL|go:"GO:0034719"(SMN-Sm protein complex)|rcsb pdb:5XJQ|rcsb pdb:5XJR|rcsb pdb:5XJS|rcsb pdb:5XJT|rcsb pdb:5XJU|reactome:R-HSA-191859|go:"GO:0032797"(SMN complex)|refseq:NP_001284644.1|ensembl:ENSP00000305857|ensembl:ENSP00000370083|ensembl:ENSP00000370117|ensembl:ENST00000380742|ensembl:ENSP00000370118|ensembl:ENSP00000370119|ensembl:ENST00000503079|ensembl:ENSP00000428128|ensembl:ENST00000506163|ensembl:ENSP00000424926|ensembl:ENST00000611442|ensembl:ENSP00000483768|ensembl:ENST00000614240|ensembl:ENSP00000479279|ensembl:ENSP00000479920|ensembl:ENST00000614773|ensembl:ENSP00000481427|ensembl:ENSP00000483515|ensembl:ENSP00000483819|ensembl:ENST00000622158|ensembl:ENSP00000480906|ensembl:ENSP00000482966|ensembl:ENST00000624634|ensembl:ENSP00000485595|ensembl:ENST00000626847|ensembl:ENSP00000486152|ensembl:ENSP00000487421|ensembl:ENST00000628353|ensembl:ENSP00000487029|ensembl:ENST00000628642|ensembl:ENSP00000487015|ensembl:ENSP00000487206|refseq:XP_016865275.1|dip:DIP-31309N|entrezgene/locuslink:6607(identity)	ensemblfungi:YEL026W(gene)|ensemblfungi:YEL026W_mRNA(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0030490"(maturation of SSU-rRNA)|go:"GO:0030621"(U4 snRNA binding)|go:"GO:0031428"(box C/D RNP complex)|go:"GO:0032040"(small-subunit processome)|go:"GO:0034511"(U3 snoRNA binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:1905216"(positive regulation of RNA binding)|interpro:IPR002415(High mobility group-like nuclear protein)|interpro:IPR004037(Ribosomal protein L7Ae)|interpro:IPR004038(Ribosomal protein L7Ae/L30e/S12e/Gadd45)|interpro:IPR018492|interpro:IPR029064|rcsb pdb:1ZWZ|rcsb pdb:2ALE|rcsb pdb:3JCM|go:"GO:0005654"(nucleoplasm)|rcsb pdb:5GAN|rcsb pdb:5GAP|rcsb pdb:5NRL|rcsb pdb:5TZS|rcsb pdb:5WLC|rcsb pdb:5WYJ|rcsb pdb:5WYK|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:6KE6|rcsb pdb:6LQP|rcsb pdb:6LQQ|rcsb pdb:6LQR|rcsb pdb:6LQS|rcsb pdb:6LQT|rcsb pdb:6LQU|rcsb pdb:6LQV|rcsb pdb:6ND4|rcsb pdb:6ZQA|rcsb pdb:6ZQB|rcsb pdb:6ZQC|rcsb pdb:6ZQD|rcsb pdb:6ZQE|rcsb pdb:7AJT|rcsb pdb:7AJU|rcsb pdb:4NUT|reactome:R-SCE-6791226|refseq:NP_010888.1|sgd:S000000752|mint:P39990|dip:DIP-2870N|sgd:YEL026W(identity)	-	-	crc64:4489780153E8F182	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:QGivm7E8suciCWXO4l0zCUzCl2g9606	rogid:4C07wkvZ4Nts4Oxw4/L7QMkwcmE559292	intact-crc:3D873A3F2AE23D03|rigid:1WMvd1mwKFzwChd4wkZR1F0aP18	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q15311	uniprotkb:P40014	intact:EBI-749285|uniprotkb:D3DUI0|ensembl:ENSP00000019317|ensembl:ENSP00000372924	intact:EBI-22458|uniprotkb:D3DLR6|ensemblfungi:YER018C	psi-mi:rbp1_human(display_long)|uniprotkb:Ral-interacting protein 1(gene name synonym)|uniprotkb:76 kDa Ral-interacting protein(gene name synonym)|uniprotkb:Dinitrophenyl S-glutathione ATPase(gene name synonym)|uniprotkb:RALBP1(gene name)|psi-mi:RALBP1(display_short)|uniprotkb:RLIP1(gene name synonym)|uniprotkb:RLIP76(gene name synonym)|uniprotkb:RLIP(gene name synonym)	psi-mi:spc25_yeast(display_long)|uniprotkb:YER018C(locus name)|uniprotkb:SPC25(gene name)|psi-mi:SPC25(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11530296|imex:IM-24995-833	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006779.1|ensembl:ENSG00000017797(gene)|ensembl:ENST00000019317(transcript)|ensembl:ENST00000383432(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0006935"(chemotaxis)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008559"(ABC-type xenobiotic transporter activity)|go:"GO:0015431"(ABC-type glutathione S-conjugate transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032489"(regulation of Cdc42 protein signal transduction)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0055085"(transmembrane transport)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:1900753"(doxorubicin transport)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR000198(RhoGAP)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR039767|mint:Q15311|rcsb pdb:2KWH|rcsb pdb:2KWI|rcsb pdb:2MBG|rcsb pdb:6ZQT|rcsb pdb:6ZRN|reactome:R-HSA-9013148|reactome:R-HSA-9013149|entrezgene/locuslink:10928(identity)	refseq:NP_010934.3|sgd:S000000820|dip:DIP-2990N|mint:P40014|ensemblfungi:YER018C(gene)|ensemblfungi:YER018C_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0051301"(cell division)|go:"GO:0098653"(centromere clustering)|interpro:IPR038066|rcsb pdb:2FTX|rcsb pdb:2FV4|rcsb pdb:4GEQ|rcsb pdb:5T6J|rcsb pdb:5TCS|rcsb pdb:5TD8|rcsb pdb:7KDF|sgd:YER018C(identity)	-	-	crc64:1BED6CCFF330A5D8	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:6u1yy+UdGWJbJ9SiItSAp+CqeVk9606	rogid:i5gKRZA7GAjnCVzuX/qP8YmpQRA559292	intact-crc:0029754294AB952B|rigid:HtFQGc/1uQod6UrVVKxZtrNLaK0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40014	uniprotkb:P37198	intact:EBI-22458|uniprotkb:D3DLR6|ensemblfungi:YER018C	intact:EBI-347978|intact:EBI-28983799|ensembl:ENSP00000305503|ensembl:ENSP00000407331|ensembl:ENSP00000471191|ensembl:ENSP00000473192|uniprotkb:Q6GTM2|uniprotkb:Q503A4|uniprotkb:Q96C43|uniprotkb:Q9NSL1|uniprotkb:B3KWU5	psi-mi:spc25_yeast(display_long)|uniprotkb:YER018C(locus name)|uniprotkb:SPC25(gene name)|psi-mi:SPC25(display_short)	psi-mi:nup62_human(display_long)|uniprotkb:NUP62(gene name)|psi-mi:NUP62(display_short)|uniprotkb:62 kDa nucleoporin(gene name synonym)|uniprotkb:Nucleoporin Nup62(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11530287|imex:IM-24995-832	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010934.3|sgd:S000000820|dip:DIP-2990N|mint:P40014|ensemblfungi:YER018C(gene)|ensemblfungi:YER018C_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0051301"(cell division)|go:"GO:0098653"(centromere clustering)|interpro:IPR038066|rcsb pdb:2FTX|rcsb pdb:2FV4|rcsb pdb:4GEQ|rcsb pdb:5T6J|rcsb pdb:5TCS|rcsb pdb:5TD8|rcsb pdb:7KDF|sgd:YER018C(identity)	refseq:NP_714941.1|ensembl:ENSG00000213024(gene)|ensembl:ENST00000352066(transcript)|ensembl:ENST00000422090(transcript)|ensembl:ENST00000596217(transcript)|ensembl:ENST00000597029(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005642"(annulate lamellae)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007100"(mitotic centrosome separation)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007569"(cell aging)|go:"GO:0008219"(cell death)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0003682"(chromatin binding)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0019894"(kinesin binding)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042306"(regulation of protein import into nucleus)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043069"(negative regulation of programmed cell death)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045742"(positive regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046578"(regulation of Ras protein signal transduction)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0046601"(positive regulation of centriole replication)|go:"GO:0051028"(mRNA transport)|go:"GO:0051425"(PTB domain binding)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0072686"(mitotic spindle)|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|go:"GO:0090543"(Flemming body)|go:"GO:0098534"(centriole assembly)|go:"GO:1903438"(positive regulation of mitotic cytokinetic process)|go:"GO:1904781"(positive regulation of protein localization to centrosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR007758(Nucleoporin, Nsp1-like, C-terminal)|interpro:IPR026010|interpro:IPR033072|mint:P37198|rcsb pdb:2H4D|rcsb pdb:5IJN|rcsb pdb:5IJO|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|refseq:NP_714940.1|refseq:NP_001180286.1|refseq:NP_036478.2|refseq:NP_057637.2|ensembl:ENSP00000305503|ensembl:ENSP00000407331|ensembl:ENSP00000471191|ensembl:ENSP00000473192|dip:DIP-29749N|entrezgene/locuslink:23636(identity)	-	crc64:1BED6CCFF330A5D8	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:i5gKRZA7GAjnCVzuX/qP8YmpQRA559292	rogid:v7mvKvTtVEnLMwcpUZIcdAzge009606	intact-crc:8B6383D61967427E|rigid:oeFv3L40gCjAcSxUtWPfYIyIC0Q	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40014	uniprotkb:P19012	intact:EBI-22458|uniprotkb:D3DLR6|ensemblfungi:YER018C	intact:EBI-739566|uniprotkb:Q53XV8|uniprotkb:Q9BUG4|uniprotkb:B3KQY1|uniprotkb:B3KRA2|uniprotkb:E0CX14|ensembl:ENSP00000254043|ensembl:ENSP00000377546	psi-mi:spc25_yeast(display_long)|uniprotkb:YER018C(locus name)|uniprotkb:SPC25(gene name)|psi-mi:SPC25(display_short)	psi-mi:k1c15_human(display_long)|uniprotkb:KRT15(gene name)|psi-mi:KRT15(display_short)|uniprotkb:KRTB(gene name synonym)|uniprotkb:Cytokeratin-15(gene name synonym)|uniprotkb:Keratin-15(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11530278|imex:IM-24995-831	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010934.3|sgd:S000000820|dip:DIP-2990N|mint:P40014|ensemblfungi:YER018C(gene)|ensemblfungi:YER018C_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0051301"(cell division)|go:"GO:0098653"(centromere clustering)|interpro:IPR038066|rcsb pdb:2FTX|rcsb pdb:2FV4|rcsb pdb:4GEQ|rcsb pdb:5T6J|rcsb pdb:5TCS|rcsb pdb:5TD8|rcsb pdb:7KDF|sgd:YER018C(identity)	refseq:NP_002266.2|ensembl:ENSG00000171346(gene)|ensembl:ENST00000254043(transcript)|ensembl:ENST00000393976(transcript)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0008544"(epidermis development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097110"(scaffold protein binding)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR039008|mint:P19012|reactome:R-HSA-6805567|reactome:R-HSA-6809371|entrezgene/locuslink:3866(identity)	-	crc64:1BED6CCFF330A5D8	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:i5gKRZA7GAjnCVzuX/qP8YmpQRA559292	rogid:WrZQBYQvrWcfrR5ojWXrXp6spPE9606	intact-crc:6130FE3C7E424E32|rigid:oUgxdUwOfZcG73bJAbMTmS43eWU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40014	uniprotkb:Q08379	intact:EBI-22458|uniprotkb:D3DLR6|ensemblfungi:YER018C	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	psi-mi:spc25_yeast(display_long)|uniprotkb:YER018C(locus name)|uniprotkb:SPC25(gene name)|psi-mi:SPC25(display_short)	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11530267|imex:IM-24995-830	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010934.3|sgd:S000000820|dip:DIP-2990N|mint:P40014|ensemblfungi:YER018C(gene)|ensemblfungi:YER018C_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0051301"(cell division)|go:"GO:0098653"(centromere clustering)|interpro:IPR038066|rcsb pdb:2FTX|rcsb pdb:2FV4|rcsb pdb:4GEQ|rcsb pdb:5T6J|rcsb pdb:5TCS|rcsb pdb:5TD8|rcsb pdb:7KDF|sgd:YER018C(identity)	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N|entrezgene/locuslink:2801(identity)	-	crc64:1BED6CCFF330A5D8	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2017/05/26	rogid:i5gKRZA7GAjnCVzuX/qP8YmpQRA559292	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	intact-crc:EFB4B3CB04DA950F|rigid:eJgt/sLTHxO0GUAEoQCNeFv/uvk	false	-	sufficient binding region:383-1002	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UKT9	uniprotkb:P40014	intact:EBI-747204|uniprotkb:Q8WWQ9|uniprotkb:Q8WWR0|uniprotkb:Q8WWR1|uniprotkb:Q8WWR2|uniprotkb:Q8WWR3|uniprotkb:Q8N574|uniprotkb:B4DVV5|uniprotkb:Q69BL6|uniprotkb:Q69BL7|uniprotkb:Q69BL8|uniprotkb:Q69BL9|uniprotkb:Q69BM0|uniprotkb:Q69BM1|uniprotkb:Q69BM2|uniprotkb:Q69BM3|uniprotkb:Q69BM5|ensembl:ENSP00000344544	intact:EBI-22458|uniprotkb:D3DLR6|ensemblfungi:YER018C	psi-mi:ikzf3_human(display_long)|uniprotkb:ZNFN1A3(gene name synonym)|uniprotkb:Ikaros family zinc finger protein 3(gene name synonym)|uniprotkb:IKZF3(gene name)|psi-mi:IKZF3(display_short)	psi-mi:spc25_yeast(display_long)|uniprotkb:YER018C(locus name)|uniprotkb:SPC25(gene name)|psi-mi:SPC25(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11530325|imex:IM-24995-836	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001271443.1|refseq:NP_001271444.1|refseq:NP_036613.2|refseq:NP_899051.1|refseq:NP_899052.1|refseq:NP_899053.1|refseq:NP_899054.1|refseq:NP_899055.1|refseq:NP_001271445.1|refseq:NP_001244337.1|refseq:NP_001244338.1|refseq:NP_001244339.1|refseq:NP_001244340.1|refseq:NP_001244341.1|refseq:NP_001244342.1|refseq:NP_001244343.1|ensembl:ENSG00000161405(gene)|ensembl:ENST00000346872(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007498"(mesoderm development)|go:"GO:0009617"(response to bacterium)|go:"GO:0030888"(regulation of B cell proliferation)|go:"GO:0042113"(B cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045577"(regulation of B cell differentiation)|go:"GO:0045619"(regulation of lymphocyte differentiation)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|go:"GO:0046872"(metal ion binding)|dip:DIP-56975N|entrezgene/locuslink:22806(identity)	refseq:NP_010934.3|sgd:S000000820|dip:DIP-2990N|mint:P40014|ensemblfungi:YER018C(gene)|ensemblfungi:YER018C_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0051301"(cell division)|go:"GO:0098653"(centromere clustering)|interpro:IPR038066|rcsb pdb:2FTX|rcsb pdb:2FV4|rcsb pdb:4GEQ|rcsb pdb:5T6J|rcsb pdb:5TCS|rcsb pdb:5TD8|rcsb pdb:7KDF|sgd:YER018C(identity)	-	-	crc64:1BED6CCFF330A5D8	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:2Kp6LefSLfK5VIiE6DmQusFIfMY9606	rogid:i5gKRZA7GAjnCVzuX/qP8YmpQRA559292	intact-crc:E6C970734C81CDE8|rigid:fjco9Hw8L8MpKcC5f63nO4QBPYE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8N6Y0	uniprotkb:P40014	intact:EBI-739895|uniprotkb:Q8NBX7|uniprotkb:Q96KH3|uniprotkb:Q9BYI8|uniprotkb:A8K7L6|uniprotkb:B2RCR9|ensembl:ENSP00000252597	intact:EBI-22458|uniprotkb:D3DLR6|ensemblfungi:YER018C	psi-mi:usbp1_human(display_long)|uniprotkb:USHBP1(gene name)|psi-mi:USHBP1(display_short)|uniprotkb:MCC-2(gene name synonym)|uniprotkb:AIE-75-binding protein(gene name synonym)|uniprotkb:AIEBP(gene name synonym)|uniprotkb:MCC2(gene name synonym)|uniprotkb:Mutated in colon cancer protein 2(gene name synonym)	psi-mi:spc25_yeast(display_long)|uniprotkb:YER018C(locus name)|uniprotkb:SPC25(gene name)|psi-mi:SPC25(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11530316|imex:IM-24995-835	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001284632.1|refseq:NP_114147.2|refseq:NP_001308346.1|ensembl:ENSG00000130307(gene)|ensembl:ENST00000252597(transcript)|go:"GO:0030165"(PDZ domain binding)|interpro:IPR019536|interpro:IPR040171|entrezgene/locuslink:83878(identity)	refseq:NP_010934.3|sgd:S000000820|dip:DIP-2990N|mint:P40014|ensemblfungi:YER018C(gene)|ensemblfungi:YER018C_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0051301"(cell division)|go:"GO:0098653"(centromere clustering)|interpro:IPR038066|rcsb pdb:2FTX|rcsb pdb:2FV4|rcsb pdb:4GEQ|rcsb pdb:5T6J|rcsb pdb:5TCS|rcsb pdb:5TD8|rcsb pdb:7KDF|sgd:YER018C(identity)	-	-	crc64:1BED6CCFF330A5D8	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:vY1qx73Ju/z7WDu6k1kd10ZDVRo9606	rogid:i5gKRZA7GAjnCVzuX/qP8YmpQRA559292	intact-crc:5DC9F079CDA937BB|rigid:rDgEicRDXpzi4eKB+1VHat4fpJ0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40014	uniprotkb:Q6P1W5	intact:EBI-22458|uniprotkb:D3DLR6|ensemblfungi:YER018C	intact:EBI-946029|uniprotkb:B3KVT1|uniprotkb:Q96IC8|ensembl:ENSP00000435634|uniprotkb:D3DPR3|uniprotkb:E9PJ76	psi-mi:spc25_yeast(display_long)|uniprotkb:YER018C(locus name)|uniprotkb:SPC25(gene name)|psi-mi:SPC25(display_short)	psi-mi:ca094_human(display_long)|uniprotkb:C1orf94(gene name)|psi-mi:C1orf94(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11530305|imex:IM-24995-834	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010934.3|sgd:S000000820|dip:DIP-2990N|mint:P40014|ensemblfungi:YER018C(gene)|ensemblfungi:YER018C_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0051301"(cell division)|go:"GO:0098653"(centromere clustering)|interpro:IPR038066|rcsb pdb:2FTX|rcsb pdb:2FV4|rcsb pdb:4GEQ|rcsb pdb:5T6J|rcsb pdb:5TCS|rcsb pdb:5TD8|rcsb pdb:7KDF|sgd:YER018C(identity)	refseq:NP_001128206.1|refseq:NP_116273.2|ensembl:ENSG00000142698(gene)|ensembl:ENST00000488417(transcript)|interpro:IPR031496|entrezgene/locuslink:84970(identity)	-	crc64:1BED6CCFF330A5D8	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:i5gKRZA7GAjnCVzuX/qP8YmpQRA559292	rogid:y1o4xWvTl2CBA1J7jsP7y8ZjLzM9606	intact-crc:C74170211CE8B1DD|rigid:7whOMEJOuuXKJBnESrRfZGxlaI0	false	-	sufficient binding region:191-598	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40070	uniprotkb:Q13049	intact:EBI-188|uniprotkb:Q07091|uniprotkb:D3DM18|ensemblfungi:YER112W	intact:EBI-742790|ensembl:ENSP00000363095|ensembl:ENSP00000408292|uniprotkb:Q9NQP8	psi-mi:lsm4_yeast(display_long)|uniprotkb:LSM4(gene name)|psi-mi:LSM4(display_short)|uniprotkb:SDB23(gene name synonym)|uniprotkb:USS1(gene name synonym)|uniprotkb:YER112W(locus name)	psi-mi:tri32_human(display_long)|uniprotkb:Zinc finger protein HT2A(gene name synonym)|uniprotkb:72 kDa Tat-interacting protein(gene name synonym)|uniprotkb:TRIM32(gene name)|psi-mi:TRIM32(display_short)|uniprotkb:HT2A(gene name synonym)|uniprotkb:Tripartite motif-containing protein 32(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM32(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11530354|imex:IM-24995-839	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000000914|refseq:NP_011037.3|mint:P40070|dip:DIP-848N|ensemblfungi:YER112W(gene)|ensemblfungi:YER112W_mRNA(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000932"(P-body)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005688"(U6 snRNP)|go:"GO:0005730"(nucleolus)|go:"GO:0005732"("sno(s)RNA-containing ribonucleoprotein complex")|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0008033"(tRNA processing)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0033962"(P-body assembly)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0097526"(spliceosomal tri-snRNP complex)|go:"GO:1990726"(Lsm1-7-Pat1 complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR027141|interpro:IPR034101|rcsb pdb:3JCM|rcsb pdb:4C8Q|rcsb pdb:4C92|rcsb pdb:4M75|rcsb pdb:4M77|rcsb pdb:4M78|rcsb pdb:4M7A|rcsb pdb:4M7D|rcsb pdb:5GAN|rcsb pdb:5NRL|rcsb pdb:5VSU|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:6ASO|reactome:R-SCE-430039|sgd:YER112W(identity)	go:"GO:0043621"(protein self-association)|go:"GO:0045087"(innate immune response)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051155"(positive regulation of striated muscle cell differentiation)|go:"GO:0061564"(axon development)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1902187"|go:"GO:1902230"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:1903265"(positive regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:1903883"(positive regulation of interleukin-17-mediated signaling pathway)|go:"GO:1903886"("positive regulation of chemokine (C-C motif) ligand 20 production")|go:"GO:2000147"(positive regulation of cell motility)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENSG00000119401(gene)|ensembl:ENST00000373983(transcript)|ensembl:ENST00000450136(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001894"(tissue homeostasis)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005863"(striated muscle myosin thick filament)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007014"(actin ubiquitination)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009411"(response to UV)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0017022"(myosin binding)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030957"(Tat protein binding)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034612"(response to tumor necrosis factor)|go:"GO:0042802"(identical protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|interpro:IPR000315(Zinc finger, B-box)|refseq:NP_001093149.1|refseq:XP_011516700.1|refseq:NP_036342.2|refseq:XP_005251870.1|interpro:IPR001258(NHL repeat)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR013017(NHL repeat, subgroup)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR027370|mint:Q13049|rcsb pdb:2CT2|rcsb pdb:5FEY|reactome:R-HSA-3134975|reactome:R-HSA-983168|refseq:XP_016869975.1|entrezgene/locuslink:22954(identity)	-	crc64:69CAC1F01D5BFA98	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Sz8HLaybwgxCRbeCESby3YThqeM559292	rogid:XuqprQd10kSpsuyGs+FSdzIdJ/Y9606	intact-crc:C1FD749CFC4F1DD0|rigid:e+QfnPkpuY4D6PAkml9j4dlL/tg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40045	uniprotkb:P19012	intact:EBI-22573|uniprotkb:D3DLX6|ensemblfungi:YER071C	intact:EBI-739566|uniprotkb:Q53XV8|uniprotkb:Q9BUG4|uniprotkb:B3KQY1|uniprotkb:B3KRA2|uniprotkb:E0CX14|ensembl:ENSP00000254043|ensembl:ENSP00000377546	psi-mi:tda2_yeast(display_long)|uniprotkb:YER071C(locus name)|uniprotkb:TDA2(gene name)|psi-mi:TDA2(display_short)	psi-mi:k1c15_human(display_long)|uniprotkb:KRT15(gene name)|psi-mi:KRT15(display_short)|uniprotkb:KRTB(gene name synonym)|uniprotkb:Cytokeratin-15(gene name synonym)|uniprotkb:Keratin-15(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11530345|imex:IM-24995-838	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010994.3|sgd:S000000873|dip:DIP-4134N|mint:P40045|ensemblfungi:YER071C(gene)|ensemblfungi:YER071C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0030479"(actin cortical patch)|go:"GO:0030837"(negative regulation of actin filament polymerization)|go:"GO:0043332"(mating projection tip)|go:"GO:0110131"(Aim21-Tda2 complex)|interpro:IPR005334(Tctex-1)|interpro:IPR038586|rcsb pdb:5VKY|sgd:YER071C(identity)	refseq:NP_002266.2|ensembl:ENSG00000171346(gene)|ensembl:ENST00000254043(transcript)|ensembl:ENST00000393976(transcript)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0008544"(epidermis development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097110"(scaffold protein binding)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR039008|mint:P19012|reactome:R-HSA-6805567|reactome:R-HSA-6809371|entrezgene/locuslink:3866(identity)	-	crc64:2F5CD27AF0C9AFE3	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:xlo2Qkef4nrF1u7WQ+p7SjixmFs559292	rogid:WrZQBYQvrWcfrR5ojWXrXp6spPE9606	intact-crc:1A35284D62592D57|rigid:Bj3x2ESld+NXJ5RwNeaNYdaHqco	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O76081-6	uniprotkb:P40045	intact:EBI-10178530|ensembl:ENSP00000276500	intact:EBI-22573|uniprotkb:D3DLX6|ensemblfungi:YER071C	psi-mi:o76081-6(display_long)|uniprotkb:RGS20(gene name)|psi-mi:RGS20(display_short)|uniprotkb:Gz-selective GTPase-activating protein(gene name synonym)|uniprotkb:RGSZ1(gene name synonym)|uniprotkb:Regulator of G-protein signaling Z1(gene name synonym)|uniprotkb:Regulator of Gz-selective protein signaling 1(gene name synonym)|uniprotkb:ZGAP1(gene name synonym)	psi-mi:tda2_yeast(display_long)|uniprotkb:YER071C(locus name)|uniprotkb:TDA2(gene name)|psi-mi:TDA2(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11530334|imex:IM-24995-837	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-1052678(isoform-parent)|uniprotkb:O76081-6(isoform-parent)|ensembl:ENSG00000147509(gene)|ensembl:ENST00000276500(transcript)|entrezgene/locuslink:8601(identity)	refseq:NP_010994.3|sgd:S000000873|dip:DIP-4134N|mint:P40045|ensemblfungi:YER071C(gene)|ensemblfungi:YER071C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0030479"(actin cortical patch)|go:"GO:0030837"(negative regulation of actin filament polymerization)|go:"GO:0043332"(mating projection tip)|go:"GO:0110131"(Aim21-Tda2 complex)|interpro:IPR005334(Tctex-1)|interpro:IPR038586|rcsb pdb:5VKY|sgd:YER071C(identity)	-	-	crc64:2F5CD27AF0C9AFE3	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:5ddWx+4uSAxIhugOqlfdCIOD8sM9606	rogid:xlo2Qkef4nrF1u7WQ+p7SjixmFs559292	intact-crc:F7577C8A77CEA8B5|rigid:Se6nOEof1Yp+d3QlMTxO8dcz+O4	false	sufficient binding region:25-241	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O14641	uniprotkb:P40087	intact:EBI-740850|ensembl:ENSP00000005340|uniprotkb:Q53XM0|uniprotkb:D3DTN3	intact:EBI-5717|uniprotkb:D3DM50|ensemblfungi:YER143W	psi-mi:dvl2_human(display_long)|uniprotkb:DSH homolog 2(gene name synonym)|uniprotkb:DVL2(gene name)|psi-mi:DVL2(display_short)	psi-mi:ddi1_yeast(display_long)|uniprotkb:DDI1(gene name)|psi-mi:DDI1(display_short)|uniprotkb:v-SNARE-master 1(gene name synonym)|uniprotkb:VSM1(gene name synonym)|uniprotkb:YER143W(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11530390|imex:IM-24995-843	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004413.1|ensembl:ENSG00000004975(gene)|ensembl:ENST00000005340(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005109"(frizzled binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0007507"(heart development)|go:"GO:0016235"(aggresome)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044340"(canonical Wnt signaling pathway involved in regulation of cell proliferation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0150012"(positive regulation of neuron projection arborization)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008341(Dishevelled-2 region)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:O14641|rcsb pdb:2REY|rcsb pdb:3CBX|rcsb pdb:3CBY|rcsb pdb:3CBZ|rcsb pdb:3CC0|rcsb pdb:4WIP|rcsb pdb:5LNP|rcsb pdb:5SUY|rcsb pdb:5SUZ|rcsb pdb:6IW3|rcsb pdb:6JCK|reactome:R-HSA-201681|reactome:R-HSA-201688|reactome:R-HSA-2028269|reactome:R-HSA-4086400|reactome:R-HSA-4608870|reactome:R-HSA-4641258|reactome:R-HSA-4641262|reactome:R-HSA-5099900|reactome:R-HSA-5368598|reactome:R-HSA-5663220|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9673324|ensembl:ENSP00000005340|dip:DIP-34433N|entrezgene/locuslink:1856(identity)	sgd:S000000945|refseq:NP_011070.3|dip:DIP-1216N|mint:P40087|rcsb pdb:2MRP|rcsb pdb:2MWS|rcsb pdb:2N7E|rcsb pdb:4Z2Z|rcsb pdb:5KES|ensemblfungi:YER143W(gene)|ensemblfungi:YER143W_mRNA(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0004190"(aspartic-type endopeptidase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0009306"(protein secretion)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043328"(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0072710"(response to hydroxyurea)|go:"GO:1904855"(proteasome regulatory particle binding)|interpro:IPR001995(Peptidase A2A, retrovirus, catalytic)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR019103|interpro:IPR021109|interpro:IPR033882|rcsb pdb:2I1A|rcsb pdb:2MR9|rcsb pdb:2MRO|sgd:YER143W(identity)	-	-	crc64:B43425B029B7658B	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:2Vdc8oRnT4Mz/j+EXQXrL3AszOc9606	rogid:DHcLrKv/gQNKEXCievX6k6ikKL0559292	intact-crc:AFE0EB9FCA26278F|rigid:GeUpq3+MJUcBavhPhRoJUMMCLdE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40078	uniprotkb:O14641	intact:EBI-22681|uniprotkb:D3DM32|ensemblfungi:YER126C	intact:EBI-740850|ensembl:ENSP00000005340|uniprotkb:Q53XM0|uniprotkb:D3DTN3	psi-mi:nsa2_yeast(display_long)|uniprotkb:YER126C(locus name)|uniprotkb:SYGP-ORF47(orf name)|uniprotkb:NSA2(gene name)|psi-mi:NSA2(display_short)|uniprotkb:NOP7-associated protein 2(gene name synonym)	psi-mi:dvl2_human(display_long)|uniprotkb:DSH homolog 2(gene name synonym)|uniprotkb:DVL2(gene name)|psi-mi:DVL2(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11530381|imex:IM-24995-842	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011052.1|sgd:S000000928|dip:DIP-1892N|mint:P40078|ensemblfungi:YER126C(gene)|ensemblfungi:YER126C_mRNA(transcript)|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000466"("maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0042273"(ribosomal large subunit biogenesis)|interpro:IPR022309|interpro:IPR039411|rcsb pdb:3JCT|rcsb pdb:4WJV|rcsb pdb:6ELZ|rcsb pdb:6EM1|rcsb pdb:6EM5|rcsb pdb:6FT6|rcsb pdb:6M62|rcsb pdb:6N8J|rcsb pdb:7BT6|rcsb pdb:7BTB|sgd:YER126C(identity)	refseq:NP_004413.1|ensembl:ENSG00000004975(gene)|ensembl:ENST00000005340(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005109"(frizzled binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0007507"(heart development)|go:"GO:0016235"(aggresome)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044340"(canonical Wnt signaling pathway involved in regulation of cell proliferation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0150012"(positive regulation of neuron projection arborization)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008341(Dishevelled-2 region)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:O14641|rcsb pdb:2REY|rcsb pdb:3CBX|rcsb pdb:3CBY|rcsb pdb:3CBZ|rcsb pdb:3CC0|rcsb pdb:4WIP|rcsb pdb:5LNP|rcsb pdb:5SUY|rcsb pdb:5SUZ|rcsb pdb:6IW3|rcsb pdb:6JCK|reactome:R-HSA-201681|reactome:R-HSA-201688|reactome:R-HSA-2028269|reactome:R-HSA-4086400|reactome:R-HSA-4608870|reactome:R-HSA-4641258|reactome:R-HSA-4641262|reactome:R-HSA-5099900|reactome:R-HSA-5368598|reactome:R-HSA-5663220|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9673324|ensembl:ENSP00000005340|dip:DIP-34433N|entrezgene/locuslink:1856(identity)	-	crc64:545C8B4250BCB0C9	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:ru6dofBbaVkHM+0tunQ4n36y98M559292	rogid:2Vdc8oRnT4Mz/j+EXQXrL3AszOc9606	intact-crc:E9FC2F41F6975492|rigid:tWCDx+BU2anm9C6WOZ01tGn0vL8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40075	uniprotkb:O15209	intact:EBI-16735|ensemblfungi:YER120W|uniprotkb:D3DM26	intact:EBI-723574|uniprotkb:Q5HYV4|uniprotkb:Q5STL0|uniprotkb:Q5STR7|uniprotkb:Q8WV82|ensembl:ENSP00000372683|ensembl:ENSP00000388191|ensembl:ENSP00000393514|ensembl:ENSP00000396292|ensembl:ENSP00000404403|ensembl:ENSP00000407545|uniprotkb:B0V007	psi-mi:scs2_yeast(display_long)|uniprotkb:YER120W(locus name)|uniprotkb:SCS2(gene name)|psi-mi:SCS2(display_short)|uniprotkb:VAP homolog 1(gene name synonym)|uniprotkb:Choline sensitivity suppressor protein 2(gene name synonym)	psi-mi:zbt22_human(display_long)|uniprotkb:Zinc finger protein 297(gene name synonym)|uniprotkb:Protein BING1(gene name synonym)|uniprotkb:Zinc finger and BTB domain-containing protein 22A(gene name synonym)|uniprotkb:ZBTB22(gene name)|psi-mi:ZBTB22(display_short)|uniprotkb:BING1(gene name synonym)|uniprotkb:ZBTB22A(gene name synonym)|uniprotkb:ZNF297(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11530372|imex:IM-24995-841	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011046.3|ensemblfungi:YER120W(gene)|ensemblfungi:YER120W_mRNA(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042308"(negative regulation of protein import into nucleus)|go:"GO:0048309"(endoplasmic reticulum inheritance)|go:"GO:0060304"(regulation of phosphatidylinositol dephosphorylation)|go:"GO:0005886"(plasma membrane)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0061163"(endoplasmic reticulum polarization)|go:"GO:0006348"|go:"GO:0061817"(endoplasmic reticulum-plasma membrane tethering)|go:"GO:0008654"(phospholipid biosynthetic process)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032377"(regulation of intracellular lipid transport)|go:"GO:0033149"(FFAT motif binding)|go:"GO:0071561"(nucleus-vacuole junction)|go:"GO:0090158"(endoplasmic reticulum membrane organization)|interpro:IPR000535(Major sperm protein)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016763(Vesicle-associated membrane protein)|rcsb pdb:6LP4|reactome:R-SCE-6798695|reactome:R-SCE-9609523|sgd:S000000922|dip:DIP-2272N|mint:P40075|sgd:YER120W(identity)	refseq:NP_001138810.1|refseq:NP_005444.4|ensembl:ENSG00000206280(gene)|ensembl:ENSG00000227780(gene)|ensembl:ENSG00000229253(gene)|ensembl:ENSG00000236104(gene)|ensembl:ENSG00000237056(gene)|ensembl:ENST00000418724(transcript)|ensembl:ENST00000431845(transcript)|ensembl:ENST00000445320(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR029833|interpro:IPR036236|ensembl:ENST00000383196(transcript)|ensembl:ENST00000416097(transcript)|ensembl:ENST00000418540(transcript)|dip:DIP-62047N|entrezgene/locuslink:9278(identity)	-	crc64:45390E24E31D392E	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:P5Pirj7wRxTi5bdoNs8lCzzTNPI559292	rogid:/u3Is9uJ0nS5Ru7xZKg4MqF6dzE9606	intact-crc:677666AF17A60D77|rigid:Pxr8b2kLMXZ4AHOUGCSBcjtKp3M	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96BA8	uniprotkb:P40074	intact:EBI-6942903|ensembl:ENSP00000481956|intact:MINT-268046|intact:MINT-8162577|uniprotkb:Q8N2D5|uniprotkb:Q96CP0	intact:EBI-22666|uniprotkb:D3DM25|ensemblfungi:YER119C	psi-mi:cr3l1_human(display_long)|uniprotkb:CREB3L1(gene name)|psi-mi:CREB3L1(display_short)|uniprotkb:OASIS(gene name synonym)|uniprotkb:PSEC0238(orf name)|uniprotkb:Old astrocyte specifically-induced substance(gene name synonym)	psi-mi:avt6_yeast(display_long)|uniprotkb:YER119C(locus name)|uniprotkb:AVT6(gene name)|psi-mi:AVT6(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11530363|imex:IM-24995-840	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157613(gene)|ensembl:ENST00000621158(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0070278"(extracellular matrix constituent secretion)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029805|mint:Q96BA8|reactome:R-HSA-8874211|refseq:NP_443086.1|entrezgene/locuslink:90993(identity)	refseq:NP_011044.1|sgd:S000000921|dip:DIP-4489N|ensemblfungi:YER119C(gene)|ensemblfungi:YER119C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0003333"(amino acid transmembrane transport)|go:"GO:0005290"(L-histidine transmembrane transporter activity)|go:"GO:0005302"(L-tyrosine transmembrane transporter activity)|go:"GO:0005313"(L-glutamate transmembrane transporter activity)|go:"GO:0015171"(amino acid transmembrane transporter activity)|go:"GO:0015183"(L-aspartate transmembrane transporter activity)|go:"GO:0015189"(L-lysine transmembrane transporter activity)|go:"GO:0015194"(L-serine transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032974"(amino acid transmembrane export from vacuole)|go:"GO:0055085"(transmembrane transport)|go:"GO:0061459"(L-arginine transmembrane transporter activity)|interpro:IPR013057(Amino acid transporter, transmembrane)|sgd:YER119C(identity)	-	comment:mint|function:"Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE"	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:sMWUFmBeBBCO+T0Y2CuB/un1lBg9606	rogid:KSuV+ucakPCtl1xQLMI6W54S7r0559292	intact-crc:DEDDF3ECF3F84747|rigid:ejPtOwiLtFx+6GXyn4cOSdiuTUg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40099	uniprotkb:A0A0C4DFM5	intact:EBI-2059710|uniprotkb:D3DM92|ensemblfungi:YER183C	intact:EBI-11530418|ensembl:ENSP00000239926	psi-mi:fthc_yeast(display_long)|uniprotkb:FAU1(gene name)|psi-mi:FAU1(display_short)|uniprotkb:5,10-methenyl-tetrahydrofolate synthetase(gene name synonym)|uniprotkb:YER183C(locus name)	psi-mi:a0a0c4dfm5_human(display_long)|uniprotkb:hCG_39937(orf name)|uniprotkb:MYOT(gene name)|psi-mi:MYOT(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11530422|imex:IM-24995-846	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	reactome:R-SCE-196757|refseq:NP_011110.1|sgd:S000000985|interpro:IPR002698(5-formyltetrahydrofolate cyclo-ligase)|interpro:IPR024185|interpro:IPR037171|ensemblfungi:YER183C(gene)|ensemblfungi:YER183C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0009396"(folic acid-containing compound biosynthetic process)|go:"GO:0030272"(5-formyltetrahydrofolate cyclo-ligase activity)|go:"GO:0035999"(tetrahydrofolate interconversion)|sgd:YER183C(identity)	refseq:NP_006781.1|ensembl:ENSG00000120729(gene)|ensembl:ENST00000239926(transcript)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|entrezgene/locuslink:9499(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:dS0v0wrvp9isCvc/Sp4d5aiOhnY559292	rogid:ggHzlR2dbSQfddxEwJplKIQXGK89606	intact-crc:8592638DE8C19A70|rigid:a7sWIXwPEmsQ7O7UxJl9GvBu72M	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UMX0	uniprotkb:P40092	intact:EBI-741480|uniprotkb:Q8IXS9|uniprotkb:Q8N2Q3|uniprotkb:Q9H0T8|uniprotkb:Q9H3R4|uniprotkb:Q9HAZ5|intact:EBI-28967608|ensembl:ENSP00000365576|uniprotkb:Q5T6J5|uniprotkb:Q5T6J9|uniprotkb:A0A024R284	intact:EBI-22721|uniprotkb:D3DM57|ensemblfungi:YER150W	psi-mi:ubql1_human(display_long)|uniprotkb:Protein linking IAP with cytoskeleton 1(gene name synonym)|uniprotkb:UBQLN1(gene name)|psi-mi:UBQLN1(display_short)|uniprotkb:DA41(gene name synonym)|uniprotkb:PLIC1(gene name synonym)	psi-mi:spi1_yeast(display_long)|uniprotkb:YER150W(locus name)|uniprotkb:SPI1(gene name)|psi-mi:SPI1(display_short)|uniprotkb:Stationary phase-induced protein 1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11530409|imex:IM-24995-845	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000257468|ensembl:ENSP00000257468|ensembl:ENSP00000365576|ensembl:ENSG00000135018(gene)|ensembl:ENST00000376395(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000502"(proteasome complex)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016235"(aggresome)|go:"GO:0016236"(macroautophagy)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0019900"(kinase binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035973"(aggrephagy)|go:"GO:0042802"(identical protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0097352"(autophagosome maturation)|go:"GO:1901340"(negative regulation of store-operated calcium channel activity)|go:"GO:1902175"(regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)|interpro:IPR000626(Ubiquitin)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR028430|interpro:IPR029071|mint:Q9UMX0|rcsb pdb:2JY5|rcsb pdb:2JY6|rcsb pdb:2KLC|reactome:R-HSA-8856825|refseq:NP_038466.2|refseq:NP_444295.1|dip:DIP-41629N|entrezgene/locuslink:29979(identity)	sgd:S000000952|refseq:NP_011077.1|dip:DIP-2064N|go:"GO:0071944"(cell periphery)|interpro:IPR038843|go:"GO:0031505"(fungal-type cell wall organization)|ensemblfungi:YER150W(gene)|ensemblfungi:YER150W_mRNA(transcript)|go:"GO:0005199"(structural constituent of cell wall)|go:"GO:0005576"(extracellular region)|go:"GO:0009277"(fungal-type cell wall)|go:"GO:0010447"(response to acidic pH)|go:"GO:0031225"(anchored component of membrane)|sgd:YER150W(identity)	-	-	crc64:F65B20225FE2A5ED	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:nCFfZbGCTvRYaXhQ4R99XblslvM9606	rogid:0S1OQwJ9EXGKjALQ4oF2uW7KCjc559292	intact-crc:4BA52DC1AE0FC255|rigid:01eOMBD/vl6nTSTP4Kt9aXWkDe0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8WTU0	uniprotkb:P40087	intact:EBI-748248|uniprotkb:Q7Z4U6|uniprotkb:Q8WTS3|ensembl:ENSP00000302805	intact:EBI-5717|uniprotkb:D3DM50|ensemblfungi:YER143W	psi-mi:ddi1_human(display_long)|uniprotkb:DDI1(gene name)|psi-mi:DDI1(display_short)	psi-mi:ddi1_yeast(display_long)|uniprotkb:DDI1(gene name)|psi-mi:DDI1(display_short)|uniprotkb:v-SNARE-master 1(gene name synonym)|uniprotkb:VSM1(gene name synonym)|uniprotkb:YER143W(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11530399|imex:IM-24995-844	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001001711.1|interpro:IPR000626(Ubiquitin)|interpro:IPR019103|interpro:IPR021109|interpro:IPR029071|interpro:IPR033882|rcsb pdb:3S8I|go:"GO:0097752"(regulation of DNA stability)|ensembl:ENSG00000170967(gene)|ensembl:ENST00000302259(transcript)|go:"GO:0004190"(aspartic-type endopeptidase activity)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0072711"(cellular response to hydroxyurea)|dip:DIP-60626N|entrezgene/locuslink:414301(identity)	sgd:S000000945|refseq:NP_011070.3|dip:DIP-1216N|mint:P40087|rcsb pdb:2MRP|rcsb pdb:2MWS|rcsb pdb:2N7E|rcsb pdb:4Z2Z|rcsb pdb:5KES|ensemblfungi:YER143W(gene)|ensemblfungi:YER143W_mRNA(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0004190"(aspartic-type endopeptidase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0009306"(protein secretion)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043328"(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0072710"(response to hydroxyurea)|go:"GO:1904855"(proteasome regulatory particle binding)|interpro:IPR001995(Peptidase A2A, retrovirus, catalytic)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR019103|interpro:IPR021109|interpro:IPR033882|rcsb pdb:2I1A|rcsb pdb:2MR9|rcsb pdb:2MRO|sgd:YER143W(identity)	-	-	crc64:B43425B029B7658B	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:000xGRvL5rBRHv7/sbuzB7i7Wtc9606	rogid:DHcLrKv/gQNKEXCievX6k6ikKL0559292	intact-crc:98B26D9E780197B1|rigid:wvG9/y0FG/QD7dqPs2aJuOh5m3I	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P63279	uniprotkb:P40151	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	intact:EBI-29152|uniprotkb:D6W0X2|ensemblfungi:YNL218W	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:wrip1_yeast(display_long)|uniprotkb:Maintenance of genome stability protein 1(gene name synonym)|uniprotkb:YNL218W(locus name)|uniprotkb:N1302(orf name)|uniprotkb:MGS1(gene name)|psi-mi:MGS1(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11530459|imex:IM-24995-850	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N|entrezgene/locuslink:7329(identity)	refseq:NP_014181.1|sgd:S000005162|dip:DIP-1638N|ensemblfungi:YNL218W(gene)|ensemblfungi:YNL218W_mRNA(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0017116"(single-stranded DNA helicase activity)|go:"GO:0033567"(DNA replication, Okazaki fragment processing)|go:"GO:0046872"(metal ion binding)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR006642(Zinc finger, Rad18-type putative)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR021886|interpro:IPR027417|interpro:IPR032423|sgd:YNL218W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	rogid:p3Wxu3/I3MK3y5fH85a0FFsg2Qo559292	intact-crc:902E08BF8C9467B8|rigid:F75dw3xBEpoULeIzUTw1/2dCaaU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O60684	uniprotkb:P40151	intact:EBI-359923|uniprotkb:Q5VVU3|uniprotkb:B2RDC7|ensembl:ENSP00000362728|uniprotkb:D3DPP5	intact:EBI-29152|uniprotkb:D6W0X2|ensemblfungi:YNL218W	psi-mi:ima7_human(display_long)|uniprotkb:KPNA6(gene name)|psi-mi:KPNA6(display_short)|uniprotkb:IPOA7(gene name synonym)|uniprotkb:Karyopherin subunit alpha-6(gene name synonym)	psi-mi:wrip1_yeast(display_long)|uniprotkb:Maintenance of genome stability protein 1(gene name synonym)|uniprotkb:YNL218W(locus name)|uniprotkb:N1302(orf name)|uniprotkb:MGS1(gene name)|psi-mi:MGS1(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11530450|imex:IM-24995-849	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_036448.1|ensembl:ENSG00000025800(gene)|ensembl:ENST00000373625(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0016020"(membrane)|go:"GO:0019079"(viral genome replication)|go:"GO:0030682"(mitigation of host defenses by symbiont)|go:"GO:0043657"(host cell)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060135"(maternal process involved in female pregnancy)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0075506"(entry of viral genome into host nucleus through nuclear pore complex via importin)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:1903902"(positive regulation of viral life cycle)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|mint:O60684|rcsb pdb:4UAD|dip:DIP-27609N|entrezgene/locuslink:23633(identity)	refseq:NP_014181.1|sgd:S000005162|dip:DIP-1638N|ensemblfungi:YNL218W(gene)|ensemblfungi:YNL218W_mRNA(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0017116"(single-stranded DNA helicase activity)|go:"GO:0033567"(DNA replication, Okazaki fragment processing)|go:"GO:0046872"(metal ion binding)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR006642(Zinc finger, Rad18-type putative)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR021886|interpro:IPR027417|interpro:IPR032423|sgd:YNL218W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:3NsSIcE6BHIqYlvfGRolUKD/5uc9606	rogid:p3Wxu3/I3MK3y5fH85a0FFsg2Qo559292	intact-crc:7B3CCD50B1EA7095|rigid:V7syCjAy9ACvfvoaFtDSyAjbkwI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96BA8	uniprotkb:P40107	intact:EBI-6942903|ensembl:ENSP00000481956|intact:MINT-268046|intact:MINT-8162577|uniprotkb:Q8N2D5|uniprotkb:Q96CP0	intact:EBI-7764|uniprotkb:D6VVB0|ensemblfungi:YGL225W	psi-mi:cr3l1_human(display_long)|uniprotkb:CREB3L1(gene name)|psi-mi:CREB3L1(display_short)|uniprotkb:OASIS(gene name synonym)|uniprotkb:PSEC0238(orf name)|uniprotkb:Old astrocyte specifically-induced substance(gene name synonym)	psi-mi:gmt1_yeast(display_long)|uniprotkb:VRG4(gene name)|psi-mi:VRG4(display_short)|uniprotkb:MCD3(gene name synonym)|uniprotkb:VAN2(gene name synonym)|uniprotkb:GOG5(gene name synonym)|uniprotkb:LDB3(gene name synonym)|uniprotkb:Vanadate resistance glycosylation protein 4(gene name synonym)|uniprotkb:Low dye-binding protein 3(gene name synonym)|uniprotkb:Morphogenesis checkpoint-dependent protein 3(gene name synonym)|uniprotkb:VIG4(gene name synonym)|uniprotkb:YGL225W(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11530440|imex:IM-24995-848	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157613(gene)|ensembl:ENST00000621158(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0070278"(extracellular matrix constituent secretion)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029805|mint:Q96BA8|reactome:R-HSA-8874211|refseq:NP_443086.1|entrezgene/locuslink:90993(identity)	refseq:NP_011290.1|sgd:S000003193|dip:DIP-5108N|ensemblfungi:YGL225W(gene)|ensemblfungi:YGL225W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005458"(GDP-mannose transmembrane transporter activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0008643"(carbohydrate transport)|go:"GO:0015297"(antiporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:1990570"(GDP-mannose transmembrane transport)|interpro:IPR038736|rcsb pdb:5OGE|rcsb pdb:5OGK|rcsb pdb:6QSK|sgd:YGL225W(identity)	-	comment:mint|function:"Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE"	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:sMWUFmBeBBCO+T0Y2CuB/un1lBg9606	rogid:ZYzY/DU+8rq6BJZz/a4LlZa8I4w559292	intact-crc:CD50D35F1CFCE947|rigid:ZzXUPAYRI5Hrp+MRYH8Rif5ZS9A	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P13196	uniprotkb:P40099	intact:EBI-3905054|ensembl:ENSP00000309259|ensembl:ENSP00000378416|ensembl:ENSP00000417719|ensembl:ENSP00000418779	intact:EBI-2059710|uniprotkb:D3DM92|ensemblfungi:YER183C	psi-mi:hem1_human(display_long)|uniprotkb:ALAS1(gene name)|psi-mi:ALAS1(display_short)|uniprotkb:ALAS3(gene name synonym)|uniprotkb:ALASH(gene name synonym)|uniprotkb:5-aminolevulinic acid synthase 1(gene name synonym)|uniprotkb:Delta-ALA synthase 1(gene name synonym)|uniprotkb:Delta-aminolevulinate synthase 1(gene name synonym)|uniprotkb:OK/SW-cl.121(orf name)	psi-mi:fthc_yeast(display_long)|uniprotkb:FAU1(gene name)|psi-mi:FAU1(display_short)|uniprotkb:5,10-methenyl-tetrahydrofolate synthetase(gene name synonym)|uniprotkb:YER183C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11530431|imex:IM-24995-847	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001291372.1|refseq:NP_001291373.1|refseq:NP_000679.1|refseq:NP_954635.1|go:"GO:0006783"(heme biosynthetic process)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0042541"(hemoglobin biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0048821"(erythrocyte development)|ensembl:ENSG00000023330(gene)|ensembl:ENST00000310271(transcript)|ensembl:ENST00000394965(transcript)|ensembl:ENST00000469224(transcript)|ensembl:ENST00000484952(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0003870"(5-aminolevulinate synthase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|interpro:IPR001917(Aminotransferase, class-II, pyridoxal-phosphate binding site)|interpro:IPR004839(Aminotransferase, class I and II)|interpro:IPR010961(Tetrapyrrole biosynthesis, 5-aminolevulinic acid synthase)|interpro:IPR015118(5-aminolevulinate synthase presequence)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|mint:P13196|reactome:R-HSA-189451|reactome:R-HSA-1989781|reactome:R-HSA-2151201|go:"GO:0006782"(protoporphyrinogen IX biosynthetic process)|entrezgene/locuslink:211(identity)	reactome:R-SCE-196757|refseq:NP_011110.1|sgd:S000000985|interpro:IPR002698(5-formyltetrahydrofolate cyclo-ligase)|interpro:IPR024185|interpro:IPR037171|ensemblfungi:YER183C(gene)|ensemblfungi:YER183C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0009396"(folic acid-containing compound biosynthetic process)|go:"GO:0030272"(5-formyltetrahydrofolate cyclo-ligase activity)|go:"GO:0035999"(tetrahydrofolate interconversion)|sgd:YER183C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:HFjJ6zrRF9UYD7LMB6A3CcxcS7c9606	rogid:dS0v0wrvp9isCvc/Sp4d5aiOhnY559292	intact-crc:1A8E968562F19ADE|rigid:ux1CwXxyarshXQ76Iz25Fcf2c8A	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96BA8	uniprotkb:P40260	intact:EBI-6942903|ensembl:ENSP00000481956|intact:MINT-268046|intact:MINT-8162577|uniprotkb:Q8N2D5|uniprotkb:Q96CP0	intact:EBI-10714|ensemblfungi:YGR121C|uniprotkb:D6VUQ2	psi-mi:cr3l1_human(display_long)|uniprotkb:CREB3L1(gene name)|psi-mi:CREB3L1(display_short)|uniprotkb:OASIS(gene name synonym)|uniprotkb:PSEC0238(orf name)|uniprotkb:Old astrocyte specifically-induced substance(gene name synonym)	psi-mi:mep1_yeast(display_long)|uniprotkb:MEP1(gene name)|psi-mi:MEP1(display_short)|uniprotkb:YGR121C(locus name)|uniprotkb:G6331(orf name)|uniprotkb:AMT1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11530495|imex:IM-24995-854	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157613(gene)|ensembl:ENST00000621158(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0070278"(extracellular matrix constituent secretion)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029805|mint:Q96BA8|reactome:R-HSA-8874211|refseq:NP_443086.1|entrezgene/locuslink:90993(identity)	ensemblfungi:YGR121C(gene)|ensemblfungi:YGR121C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008519"(ammonium transmembrane transporter activity)|go:"GO:0015696"|go:"GO:0019740"(nitrogen utilization)|interpro:IPR001905(Ammonium transporter)|interpro:IPR018047|interpro:IPR024041|interpro:IPR029020|sgd:S000003353|refseq:NP_011636.3|mint:P40260|dip:DIP-5530N|sgd:YGR121C(identity)	-	comment:mint|function:"Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE"	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:sMWUFmBeBBCO+T0Y2CuB/un1lBg9606	rogid:VnoBl5jhQD24N0SbCLv68HCwl1U559292	intact-crc:A18E15D038647189|rigid:ZKdgQdgjnCX7kncCJGtxbUP2YH8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40217	uniprotkb:O75821	intact:EBI-8951|ensemblfungi:YMR146C|uniprotkb:D6VZW8	intact:EBI-366632|uniprotkb:O14801|uniprotkb:Q969U5|intact:EBI-28974438|ensembl:ENSP00000253108	psi-mi:eif3i_yeast(display_long)|uniprotkb:TIF34(gene name)|psi-mi:TIF34(display_short)|uniprotkb:YMR146C(locus name)|uniprotkb:YM9375.16C(orf name)|uniprotkb:Eukaryotic translation initiation factor 3 39 kDa subunit(gene name synonym)	psi-mi:eif3g_human(display_long)|uniprotkb:EIF3G(gene name)|psi-mi:EIF3G(display_short)|uniprotkb:EIF3S4(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 4(gene name synonym)|uniprotkb:eIF-3-delta(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 RNA-binding subunit(gene name synonym)|uniprotkb:eIF3 p44(gene name synonym)|uniprotkb:eIF3 p42(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11530486|imex:IM-24995-853	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YMR146C(gene)|ensemblfungi:YMR146C_mRNA(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0002183"(cytoplasmic translational initiation)|go:"GO:0002188"(translation reinitiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0043614"(multi-eIF complex)|go:"GO:0071541"(eukaryotic translation initiation factor 3 complex, eIF3m)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR027525|interpro:IPR036322|rcsb pdb:3JAP|rcsb pdb:3JAQ|rcsb pdb:3ZWL|rcsb pdb:5A5U|rcsb pdb:6FYX|rcsb pdb:6FYY|rcsb pdb:6GSM|rcsb pdb:6GSN|rcsb pdb:6ZCE|rcsb pdb:6ZU9|reactome:R-SCE-156827|reactome:R-SCE-72649|reactome:R-SCE-72695|reactome:R-SCE-72702|refseq:NP_013866.1|sgd:S000004754|mint:P40217|dip:DIP-2520N|sgd:YMR146C(identity)	ensembl:ENSP00000253108|refseq:NP_003746.2|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0075525"(viral translational termination-reinitiation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR017334(Translation initiation factor 3, RNA-binding subunit)|interpro:IPR024675|interpro:IPR034240|interpro:IPR035979|mint:O75821|rcsb pdb:2CQ0|rcsb pdb:2MJC|rcsb pdb:5K0Y|rcsb pdb:6YBS|rcsb pdb:6ZMW|reactome:R-HSA-156827|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|ensembl:ENSG00000130811(gene)|ensembl:ENST00000253108(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|dip:DIP-31115N|entrezgene/locuslink:8666(identity)	-	crc64:E6C0D0B275E87622	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:yiEGZUsT5RdaocsqZq2BUELIsR8559292	rogid:ZHm8Il08Zyb6kFAavZo4tnuUN4g9606	intact-crc:0345F6818B2503FF|rigid:vzNfpj9VStpaFdO/Ylg0KfiZkgA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40185	uniprotkb:Q12800	intact:EBI-11022|ensemblfungi:YIL051C|uniprotkb:D6VVN0	intact:EBI-717422|uniprotkb:Q12801|uniprotkb:Q9UD77|uniprotkb:A8K5E9|uniprotkb:Q9UD75|ensembl:ENSP00000257915	psi-mi:mmf1_yeast(display_long)|uniprotkb:MMF1(gene name)|psi-mi:MMF1(display_short)|uniprotkb:IBM1(gene name synonym)|uniprotkb:Maintenance of mitochondrial function 1(gene name synonym)|uniprotkb:Isoleucine biosynthesis and maintenance of intact mitochondria 1(gene name synonym)|uniprotkb:YIL051C(locus name)	psi-mi:tfcp2_human(display_long)|uniprotkb:Transcription factor LSF(gene name synonym)|uniprotkb:SAA3 enhancer factor(gene name synonym)|uniprotkb:TFCP2(gene name)|psi-mi:TFCP2(display_short)|uniprotkb:LSF(gene name synonym)|uniprotkb:SEF(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11530477|imex:IM-24995-852	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YIL051C(gene)|ensemblfungi:YIL051C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0009097"(isoleucine biosynthetic process)|go:"GO:0019239"(deaminase activity)|go:"GO:0032543"(mitochondrial translation)|go:"GO:1901565"(organonitrogen compound catabolic process)|interpro:IPR006056(YjgF-like protein)|interpro:IPR006175(Endoribonuclease L-PSP)|interpro:IPR019897|interpro:IPR035959|rcsb pdb:3QUW|refseq:NP_012213.3|sgd:S000001313|mint:P40185|dip:DIP-4714N|sgd:YIL051C(identity)	refseq:NP_001166923.1|refseq:NP_001166924.1|refseq:NP_005644.2|ensembl:ENSG00000135457(gene)|ensembl:ENST00000257915(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR007604(CP2 transcription factor)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR037599|interpro:IPR041418|mint:Q12800|entrezgene/locuslink:7024(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:N825kjK9jblhOOg4MZP7RmQXN1M559292	rogid:M7mQ08NDYxuawmUEKRgjSdIr+Og9606	intact-crc:2114420D2FB61100|rigid:nuT+IJit7wXV1lpOKf+gK5hVN+I	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96BA8	uniprotkb:P40152	intact:EBI-6942903|ensembl:ENSP00000481956|intact:MINT-268046|intact:MINT-8162577|uniprotkb:Q8N2D5|uniprotkb:Q96CP0	intact:EBI-29148|uniprotkb:D6W0X3|ensemblfungi:YNL217W	psi-mi:cr3l1_human(display_long)|uniprotkb:CREB3L1(gene name)|psi-mi:CREB3L1(display_short)|uniprotkb:OASIS(gene name synonym)|uniprotkb:PSEC0238(orf name)|uniprotkb:Old astrocyte specifically-induced substance(gene name synonym)	psi-mi:ynv7_yeast(display_long)|uniprotkb:N1306(orf name)|uniprotkb:YNL217W(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11530468|imex:IM-24995-851	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157613(gene)|ensembl:ENST00000621158(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0070278"(extracellular matrix constituent secretion)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029805|mint:Q96BA8|reactome:R-HSA-8874211|refseq:NP_443086.1|entrezgene/locuslink:90993(identity)	refseq:NP_014182.1|sgd:S000005161|dip:DIP-4934N|ensemblfungi:YNL217W(gene)|ensemblfungi:YNL217W_mRNA(transcript)|go:"GO:0000298"(endopolyphosphatase activity)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005775"(vacuolar lumen)|go:"GO:0006798"(polyphosphate catabolic process)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR029052|sgd:YNL217W(identity)	-	comment:mint|function:"Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE"	crc64:D69F22A94C4C6684	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:sMWUFmBeBBCO+T0Y2CuB/un1lBg9606	rogid:t4PQ2ND+pPVb7QdkoNSpFPNr+SE559292	intact-crc:ED13D3532FF8C689|rigid:hlK3iuu+1zoyfgZlPVMD9BxN8lk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40302	uniprotkb:O75936	intact:EBI-13955|ensemblfungi:YMR314W|uniprotkb:D6W0E1	intact:EBI-715662|uniprotkb:Q6IBJ2|ensembl:ENSP00000263182|ensembl:ENSP00000433772|ensembl:ENSP00000434918|ensembl:ENSP00000435781|uniprotkb:B2R8L7|uniprotkb:D3DQZ1	psi-mi:psa6_yeast(display_long)|uniprotkb:PRE5(gene name)|psi-mi:PRE5(display_short)|uniprotkb:YMR314W(locus name)|uniprotkb:YM9924.06(orf name)|uniprotkb:Proteasome component PRE5(gene name synonym)|uniprotkb:Macropain subunit PRE5(gene name synonym)|uniprotkb:Proteinase YSCE subunit PRE5(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit PRE5(gene name synonym)	psi-mi:bodg_human(display_long)|uniprotkb:Gamma-butyrobetaine,2-oxoglutarate dioxygenase(gene name synonym)|uniprotkb:Gamma-butyrobetaine hydroxylase(gene name synonym)|uniprotkb:BBOX1(gene name)|psi-mi:BBOX1(display_short)|uniprotkb:BBH(gene name synonym)|uniprotkb:BBOX(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11530524|imex:IM-24995-857	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:4Y8T|rcsb pdb:4Y8U|rcsb pdb:4Y9Y|rcsb pdb:4Y9Z|rcsb pdb:4YA0|rcsb pdb:4YA1|rcsb pdb:4YA2|rcsb pdb:4YA3|rcsb pdb:4YA4|rcsb pdb:4YA5|rcsb pdb:4Y7X|rcsb pdb:4Y7Y|rcsb pdb:4Y80|rcsb pdb:4Y81|rcsb pdb:4Y82|rcsb pdb:4Y84|rcsb pdb:4Y8G|rcsb pdb:4Y8H|rcsb pdb:4Y8I|rcsb pdb:4Y8J|rcsb pdb:4Y8K|rcsb pdb:4Y8L|rcsb pdb:4Y8M|rcsb pdb:4Y8N|rcsb pdb:4Y8O|rcsb pdb:4Y8P|rcsb pdb:4Y8Q|rcsb pdb:4Y8R|rcsb pdb:4Y8S|rcsb pdb:5FG7|rcsb pdb:5FG9|rcsb pdb:5FGA|rcsb pdb:4YA7|rcsb pdb:4YA9|rcsb pdb:4Z1L|rcsb pdb:5A5B|rcsb pdb:5AHJ|rcsb pdb:5BOU|rcsb pdb:5BXL|rcsb pdb:5BXN|rcsb pdb:5CGF|rcsb pdb:5CGG|rcsb pdb:5CGH|rcsb pdb:5CGI|rcsb pdb:5CZ4|rcsb pdb:5CZ5|rcsb pdb:5CZ6|rcsb pdb:5CZ7|rcsb pdb:5CZ8|rcsb pdb:5CZ9|rcsb pdb:5CZA|rcsb pdb:5D0S|rcsb pdb:5D0T|rcsb pdb:5D0V|rcsb pdb:5D0W|rcsb pdb:5D0X|rcsb pdb:5D0Z|rcsb pdb:5DKI|rcsb pdb:5DKJ|rcsb pdb:5FGD|rcsb pdb:3HYE|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:3MG0|rcsb pdb:3MG4|rcsb pdb:3MG6|rcsb pdb:3MG7|rcsb pdb:3MG8|rcsb pdb:3NZJ|rcsb pdb:3NZW|rcsb pdb:3NZX|rcsb pdb:3OEU|rcsb pdb:3OEV|rcsb pdb:3OKJ|rcsb pdb:3SDI|rcsb pdb:3SDK|rcsb pdb:3SHJ|rcsb pdb:3TDD|rcsb pdb:3UN4|rcsb pdb:3UN8|rcsb pdb:3WXR|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:4EU2|rcsb pdb:4FZC|rcsb pdb:4FZG|rcsb pdb:4G4S|rcsb pdb:4GK7|rcsb pdb:4HNP|rcsb pdb:4HRC|rcsb pdb:4HRD|rcsb pdb:4INR|rcsb pdb:4INT|rcsb pdb:4INU|rcsb pdb:4J70|rcsb pdb:4JSQ|rcsb pdb:4JSU|rcsb pdb:4JT0|rcsb pdb:4LQI|rcsb pdb:4LTC|rcsb pdb:4NNN|rcsb pdb:4NNW|rcsb pdb:4NO1|rcsb pdb:4NO6|rcsb pdb:4NO8|rcsb pdb:4NO9|rcsb pdb:5FGE|rcsb pdb:5FGF|rcsb pdb:5FGG|rcsb pdb:5FGH|rcsb pdb:5FGI|rcsb pdb:5FHS|rcsb pdb:5JHR|rcsb pdb:5JHS|rcsb pdb:5L52|rcsb pdb:5L54|rcsb pdb:5L55|rcsb pdb:5L5A|rcsb pdb:5L5B|rcsb pdb:5L5D|rcsb pdb:5L5E|rcsb pdb:5L5F|rcsb pdb:5L5H|rcsb pdb:5L5I|rcsb pdb:5L5J|rcsb pdb:5L5O|rcsb pdb:5L5P|rcsb pdb:5L5Q|rcsb pdb:5L5R|rcsb pdb:4Q1S|rcsb pdb:4QBY|rcsb pdb:4QLQ|rcsb pdb:4QLS|rcsb pdb:4QLT|rcsb pdb:4QLU|rcsb pdb:4QLV|rcsb pdb:4QUX|rcsb pdb:4QUY|rcsb pdb:4QV0|rcsb pdb:4QV1|rcsb pdb:4QV3|rcsb pdb:4QV4|rcsb pdb:4QV5|rcsb pdb:4QV6|rcsb pdb:4QV7|rcsb pdb:4QV8|rcsb pdb:4QV9|rcsb pdb:4QVL|ensemblfungi:YMR314W(gene)|ensemblfungi:YMR314W_mRNA(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0042175"(nuclear outer membrane-endoplasmic reticulum membrane network)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR035144|rcsb pdb:1FNT|rcsb pdb:1G0U|rcsb pdb:1G65|rcsb pdb:1JD2|rcsb pdb:1RYP|rcsb pdb:1Z7Q|rcsb pdb:2F16|rcsb pdb:2FAK|rcsb pdb:2GPL|rcsb pdb:2ZCY|rcsb pdb:3BDM|rcsb pdb:3D29|rcsb pdb:3DY3|rcsb pdb:3DY4|rcsb pdb:3E47|rcsb pdb:3GPJ|rcsb pdb:3GPT|rcsb pdb:3GPW|rcsb pdb:4QVM|rcsb pdb:4QVN|rcsb pdb:4QVP|rcsb pdb:4QVQ|rcsb pdb:4QVV|rcsb pdb:4QVW|rcsb pdb:4QVY|rcsb pdb:4QW0|rcsb pdb:4QW1|rcsb pdb:4QW3|rcsb pdb:4QW4|rcsb pdb:4QW5|rcsb pdb:4QW6|rcsb pdb:4QW7|rcsb pdb:4QWF|rcsb pdb:4QWG|rcsb pdb:4QWI|rcsb pdb:4QWJ|rcsb pdb:4QWK|rcsb pdb:4QWL|rcsb pdb:4QWR|rcsb pdb:4QWS|rcsb pdb:4QWU|rcsb pdb:4QWX|rcsb pdb:4QXJ|rcsb pdb:4QZ0|rcsb pdb:4QZ1|rcsb pdb:4QZ2|rcsb pdb:4QZ3|rcsb pdb:4QZ4|rcsb pdb:4QZ5|rcsb pdb:4QZ6|rcsb pdb:4QZ7|rcsb pdb:4QZW|rcsb pdb:4QZX|rcsb pdb:4QZZ|rcsb pdb:4R00|rcsb pdb:4R02|rcsb pdb:4R17|rcsb pdb:4R18|rcsb pdb:4RUR|rcsb pdb:4V7O|rcsb pdb:4X6Z|rcsb pdb:4Y69|rcsb pdb:4Y6A|rcsb pdb:4Y6V|rcsb pdb:4Y6Z|rcsb pdb:4Y70|rcsb pdb:4Y74|rcsb pdb:4Y75|rcsb pdb:4Y77|rcsb pdb:4Y78|rcsb pdb:4Y7W|rcsb pdb:5LTT|rcsb pdb:5M2B|rcsb pdb:5MP9|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5NIF|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6G7F|rcsb pdb:6G8M|rcsb pdb:6G8N|rcsb pdb:6GOP|rcsb pdb:6H39|rcsb pdb:6HTB|rcsb pdb:6HTC|rcsb pdb:6HTD|rcsb pdb:6HTP|rcsb pdb:6HTR|rcsb pdb:6HUB|rcsb pdb:6HUC|rcsb pdb:6HUQ|rcsb pdb:6HUU|rcsb pdb:6HUV|rcsb pdb:6HV3|rcsb pdb:6HV4|rcsb pdb:6HV5|rcsb pdb:6HV7|rcsb pdb:6HVA|rcsb pdb:6HVR|rcsb pdb:6HVS|rcsb pdb:6HVT|rcsb pdb:6HVU|rcsb pdb:6HVV|rcsb pdb:5L5S|rcsb pdb:5L5T|rcsb pdb:5L5U|rcsb pdb:5L5V|rcsb pdb:5L5W|rcsb pdb:5L5X|rcsb pdb:5L5Y|rcsb pdb:5L5Z|rcsb pdb:5L60|rcsb pdb:5L61|rcsb pdb:5L62|rcsb pdb:5L63|rcsb pdb:5L64|rcsb pdb:5L65|rcsb pdb:5L66|rcsb pdb:5L67|rcsb pdb:5L68|rcsb pdb:5L69|rcsb pdb:5L6A|rcsb pdb:5L6B|rcsb pdb:5L6C|rcsb pdb:5LAI|rcsb pdb:5LAJ|rcsb pdb:6HVW|rcsb pdb:6HVX|rcsb pdb:6HVY|rcsb pdb:6HW0|rcsb pdb:6HW3|rcsb pdb:6HW4|rcsb pdb:6HW5|rcsb pdb:6HW6|rcsb pdb:6HW7|rcsb pdb:6HW8|rcsb pdb:6HW9|rcsb pdb:6HWA|rcsb pdb:6HWB|rcsb pdb:6HWC|rcsb pdb:6HWD|rcsb pdb:6HWE|rcsb pdb:6HWF|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2X|rcsb pdb:6J30|rcsb pdb:6ZOU|rcsb pdb:6ZP6|rcsb pdb:6ZP8|rcsb pdb:7LS5|rcsb pdb:7LS6|rcsb pdb:7LSX|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|rcsb pdb:6J2Q|refseq:NP_014045.1|sgd:S000004931|mint:P40302|dip:DIP-1528N|sgd:YMR314W(identity)	refseq:NP_003977.1|refseq:XP_005253216.1|refseq:XP_005253217.1|refseq:XP_005253218.1|ensembl:ENSG00000129151(gene)|ensembl:ENST00000263182(transcript)|ensembl:ENST00000525090(transcript)|ensembl:ENST00000528583(transcript)|ensembl:ENST00000529202(transcript)|go:"GO:0005506"(iron ion binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008336"(gamma-butyrobetaine dioxygenase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0045329"(carnitine biosynthetic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR003819(Taurine catabolism dioxygenase TauD/TfdA)|interpro:IPR010376(Protein of unknown function DUF971)|interpro:IPR012775(Gamma-butyrobetaine,2-oxoglutarate dioxygenase)|interpro:IPR038492|interpro:IPR042098|mint:O75936|rcsb pdb:3MS5|rcsb pdb:3N6W|rcsb pdb:3O2G|rcsb pdb:4BG1|rcsb pdb:4BGK|rcsb pdb:4BGM|rcsb pdb:4BHF|rcsb pdb:4BHG|rcsb pdb:4BHI|rcsb pdb:4C5W|rcsb pdb:4C8R|rcsb pdb:4CWD|reactome:R-HSA-71262|refseq:XP_011518704.1|refseq:XP_016873892.1|entrezgene/locuslink:8424(identity)	-	crc64:C43CBCC1C6B9E39E	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:C9GPb0JAklkBz0t/YYqRMNEiQss559292	rogid:oEjzTzRRvj9ygqEj2pca6MxK1Jo9606	intact-crc:FDE371EF30EFB86D|rigid:l/M0DjcolNXCiU1n3A7/37FZ5p4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q7Z6G3-2	uniprotkb:P40302	intact:EBI-10172876|ensembl:ENSP00000457354|intact:EBI-14062040	intact:EBI-13955|ensemblfungi:YMR314W|uniprotkb:D6W0E1	psi-mi:q7z6g3-2(display_long)|uniprotkb:EFCBP2(gene name synonym)|uniprotkb:Neuronal calcium-binding protein 2(gene name synonym)|uniprotkb:Synaptotagmin-interacting protein 2(gene name synonym)|uniprotkb:NECAB2(gene name)|psi-mi:NECAB2(display_short)	psi-mi:psa6_yeast(display_long)|uniprotkb:PRE5(gene name)|psi-mi:PRE5(display_short)|uniprotkb:YMR314W(locus name)|uniprotkb:YM9924.06(orf name)|uniprotkb:Proteasome component PRE5(gene name synonym)|uniprotkb:Macropain subunit PRE5(gene name synonym)|uniprotkb:Proteinase YSCE subunit PRE5(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit PRE5(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11530513|imex:IM-24995-856	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000103154(gene)|ensembl:ENST00000565691(transcript)|uniprotkb:Q7Z6G3-2(isoform-parent)|intact:EBI-950070(isoform-parent)|entrezgene/locuslink:54550(identity)	rcsb pdb:4Y8T|rcsb pdb:4Y8U|rcsb pdb:4Y9Y|rcsb pdb:4Y9Z|rcsb pdb:4YA0|rcsb pdb:4YA1|rcsb pdb:4YA2|rcsb pdb:4YA3|rcsb pdb:4YA4|rcsb pdb:4YA5|rcsb pdb:4Y7X|rcsb pdb:4Y7Y|rcsb pdb:4Y80|rcsb pdb:4Y81|rcsb pdb:4Y82|rcsb pdb:4Y84|rcsb pdb:4Y8G|rcsb pdb:4Y8H|rcsb pdb:4Y8I|rcsb pdb:4Y8J|rcsb pdb:4Y8K|rcsb pdb:4Y8L|rcsb pdb:4Y8M|rcsb pdb:4Y8N|rcsb pdb:4Y8O|rcsb pdb:4Y8P|rcsb pdb:4Y8Q|rcsb pdb:4Y8R|rcsb pdb:4Y8S|rcsb pdb:5FG7|rcsb pdb:5FG9|rcsb pdb:5FGA|rcsb pdb:4YA7|rcsb pdb:4YA9|rcsb pdb:4Z1L|rcsb pdb:5A5B|rcsb pdb:5AHJ|rcsb pdb:5BOU|rcsb pdb:5BXL|rcsb pdb:5BXN|rcsb pdb:5CGF|rcsb pdb:5CGG|rcsb pdb:5CGH|rcsb pdb:5CGI|rcsb pdb:5CZ4|rcsb pdb:5CZ5|rcsb pdb:5CZ6|rcsb pdb:5CZ7|rcsb pdb:5CZ8|rcsb pdb:5CZ9|rcsb pdb:5CZA|rcsb pdb:5D0S|rcsb pdb:5D0T|rcsb pdb:5D0V|rcsb pdb:5D0W|rcsb pdb:5D0X|rcsb pdb:5D0Z|rcsb pdb:5DKI|rcsb pdb:5DKJ|rcsb pdb:5FGD|rcsb pdb:3HYE|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:3MG0|rcsb pdb:3MG4|rcsb pdb:3MG6|rcsb pdb:3MG7|rcsb pdb:3MG8|rcsb pdb:3NZJ|rcsb pdb:3NZW|rcsb pdb:3NZX|rcsb pdb:3OEU|rcsb pdb:3OEV|rcsb pdb:3OKJ|rcsb pdb:3SDI|rcsb pdb:3SDK|rcsb pdb:3SHJ|rcsb pdb:3TDD|rcsb pdb:3UN4|rcsb pdb:3UN8|rcsb pdb:3WXR|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:4EU2|rcsb pdb:4FZC|rcsb pdb:4FZG|rcsb pdb:4G4S|rcsb pdb:4GK7|rcsb pdb:4HNP|rcsb pdb:4HRC|rcsb pdb:4HRD|rcsb pdb:4INR|rcsb pdb:4INT|rcsb pdb:4INU|rcsb pdb:4J70|rcsb pdb:4JSQ|rcsb pdb:4JSU|rcsb pdb:4JT0|rcsb pdb:4LQI|rcsb pdb:4LTC|rcsb pdb:4NNN|rcsb pdb:4NNW|rcsb pdb:4NO1|rcsb pdb:4NO6|rcsb pdb:4NO8|rcsb pdb:4NO9|rcsb pdb:5FGE|rcsb pdb:5FGF|rcsb pdb:5FGG|rcsb pdb:5FGH|rcsb pdb:5FGI|rcsb pdb:5FHS|rcsb pdb:5JHR|rcsb pdb:5JHS|rcsb pdb:5L52|rcsb pdb:5L54|rcsb pdb:5L55|rcsb pdb:5L5A|rcsb pdb:5L5B|rcsb pdb:5L5D|rcsb pdb:5L5E|rcsb pdb:5L5F|rcsb pdb:5L5H|rcsb pdb:5L5I|rcsb pdb:5L5J|rcsb pdb:5L5O|rcsb pdb:5L5P|rcsb pdb:5L5Q|rcsb pdb:5L5R|rcsb pdb:4Q1S|rcsb pdb:4QBY|rcsb pdb:4QLQ|rcsb pdb:4QLS|rcsb pdb:4QLT|rcsb pdb:4QLU|rcsb pdb:4QLV|rcsb pdb:4QUX|rcsb pdb:4QUY|rcsb pdb:4QV0|rcsb pdb:4QV1|rcsb pdb:4QV3|rcsb pdb:4QV4|rcsb pdb:4QV5|rcsb pdb:4QV6|rcsb pdb:4QV7|rcsb pdb:4QV8|rcsb pdb:4QV9|rcsb pdb:4QVL|ensemblfungi:YMR314W(gene)|ensemblfungi:YMR314W_mRNA(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0042175"(nuclear outer membrane-endoplasmic reticulum membrane network)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR035144|rcsb pdb:1FNT|rcsb pdb:1G0U|rcsb pdb:1G65|rcsb pdb:1JD2|rcsb pdb:1RYP|rcsb pdb:1Z7Q|rcsb pdb:2F16|rcsb pdb:2FAK|rcsb pdb:2GPL|rcsb pdb:2ZCY|rcsb pdb:3BDM|rcsb pdb:3D29|rcsb pdb:3DY3|rcsb pdb:3DY4|rcsb pdb:3E47|rcsb pdb:3GPJ|rcsb pdb:3GPT|rcsb pdb:3GPW|rcsb pdb:4QVM|rcsb pdb:4QVN|rcsb pdb:4QVP|rcsb pdb:4QVQ|rcsb pdb:4QVV|rcsb pdb:4QVW|rcsb pdb:4QVY|rcsb pdb:4QW0|rcsb pdb:4QW1|rcsb pdb:4QW3|rcsb pdb:4QW4|rcsb pdb:4QW5|rcsb pdb:4QW6|rcsb pdb:4QW7|rcsb pdb:4QWF|rcsb pdb:4QWG|rcsb pdb:4QWI|rcsb pdb:4QWJ|rcsb pdb:4QWK|rcsb pdb:4QWL|rcsb pdb:4QWR|rcsb pdb:4QWS|rcsb pdb:4QWU|rcsb pdb:4QWX|rcsb pdb:4QXJ|rcsb pdb:4QZ0|rcsb pdb:4QZ1|rcsb pdb:4QZ2|rcsb pdb:4QZ3|rcsb pdb:4QZ4|rcsb pdb:4QZ5|rcsb pdb:4QZ6|rcsb pdb:4QZ7|rcsb pdb:4QZW|rcsb pdb:4QZX|rcsb pdb:4QZZ|rcsb pdb:4R00|rcsb pdb:4R02|rcsb pdb:4R17|rcsb pdb:4R18|rcsb pdb:4RUR|rcsb pdb:4V7O|rcsb pdb:4X6Z|rcsb pdb:4Y69|rcsb pdb:4Y6A|rcsb pdb:4Y6V|rcsb pdb:4Y6Z|rcsb pdb:4Y70|rcsb pdb:4Y74|rcsb pdb:4Y75|rcsb pdb:4Y77|rcsb pdb:4Y78|rcsb pdb:4Y7W|rcsb pdb:5LTT|rcsb pdb:5M2B|rcsb pdb:5MP9|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5NIF|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6G7F|rcsb pdb:6G8M|rcsb pdb:6G8N|rcsb pdb:6GOP|rcsb pdb:6H39|rcsb pdb:6HTB|rcsb pdb:6HTC|rcsb pdb:6HTD|rcsb pdb:6HTP|rcsb pdb:6HTR|rcsb pdb:6HUB|rcsb pdb:6HUC|rcsb pdb:6HUQ|rcsb pdb:6HUU|rcsb pdb:6HUV|rcsb pdb:6HV3|rcsb pdb:6HV4|rcsb pdb:6HV5|rcsb pdb:6HV7|rcsb pdb:6HVA|rcsb pdb:6HVR|rcsb pdb:6HVS|rcsb pdb:6HVT|rcsb pdb:6HVU|rcsb pdb:6HVV|rcsb pdb:5L5S|rcsb pdb:5L5T|rcsb pdb:5L5U|rcsb pdb:5L5V|rcsb pdb:5L5W|rcsb pdb:5L5X|rcsb pdb:5L5Y|rcsb pdb:5L5Z|rcsb pdb:5L60|rcsb pdb:5L61|rcsb pdb:5L62|rcsb pdb:5L63|rcsb pdb:5L64|rcsb pdb:5L65|rcsb pdb:5L66|rcsb pdb:5L67|rcsb pdb:5L68|rcsb pdb:5L69|rcsb pdb:5L6A|rcsb pdb:5L6B|rcsb pdb:5L6C|rcsb pdb:5LAI|rcsb pdb:5LAJ|rcsb pdb:6HVW|rcsb pdb:6HVX|rcsb pdb:6HVY|rcsb pdb:6HW0|rcsb pdb:6HW3|rcsb pdb:6HW4|rcsb pdb:6HW5|rcsb pdb:6HW6|rcsb pdb:6HW7|rcsb pdb:6HW8|rcsb pdb:6HW9|rcsb pdb:6HWA|rcsb pdb:6HWB|rcsb pdb:6HWC|rcsb pdb:6HWD|rcsb pdb:6HWE|rcsb pdb:6HWF|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2X|rcsb pdb:6J30|rcsb pdb:6ZOU|rcsb pdb:6ZP6|rcsb pdb:6ZP8|rcsb pdb:7LS5|rcsb pdb:7LS6|rcsb pdb:7LSX|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|rcsb pdb:6J2Q|refseq:NP_014045.1|sgd:S000004931|mint:P40302|dip:DIP-1528N|sgd:YMR314W(identity)	-	-	crc64:C43CBCC1C6B9E39E	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:4S7oIx6h+mKzV3EPxqcfMNqaNko9606	rogid:C9GPb0JAklkBz0t/YYqRMNEiQss559292	intact-crc:2256DB03BF7F8C47|rigid:S01jGR6LjAADiaZ9tYOiC9wrNaM	false	sufficient binding region:65-303	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:A9UHW6-2	uniprotkb:P40302	intact:EBI-9118295|ensembl:ENSP00000245551	intact:EBI-13955|ensemblfungi:YMR314W|uniprotkb:D6W0E1	psi-mi:a9uhw6-2(display_long)|uniprotkb:MIF4GD(gene name)|psi-mi:MIF4GD(display_short)|uniprotkb:SLIP1(gene name synonym)|uniprotkb:SLBP-interacting protein 1(gene name synonym)	psi-mi:psa6_yeast(display_long)|uniprotkb:PRE5(gene name)|psi-mi:PRE5(display_short)|uniprotkb:YMR314W(locus name)|uniprotkb:YM9924.06(orf name)|uniprotkb:Proteasome component PRE5(gene name synonym)|uniprotkb:Macropain subunit PRE5(gene name synonym)|uniprotkb:Proteinase YSCE subunit PRE5(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit PRE5(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11530504|imex:IM-24995-855	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-373498(isoform-parent)|ensembl:ENSG00000125457(gene)|ensembl:ENST00000245551(transcript)|uniprotkb:A9UHW6-2(isoform-parent)|entrezgene/locuslink:57409(identity)	rcsb pdb:4Y8T|rcsb pdb:4Y8U|rcsb pdb:4Y9Y|rcsb pdb:4Y9Z|rcsb pdb:4YA0|rcsb pdb:4YA1|rcsb pdb:4YA2|rcsb pdb:4YA3|rcsb pdb:4YA4|rcsb pdb:4YA5|rcsb pdb:4Y7X|rcsb pdb:4Y7Y|rcsb pdb:4Y80|rcsb pdb:4Y81|rcsb pdb:4Y82|rcsb pdb:4Y84|rcsb pdb:4Y8G|rcsb pdb:4Y8H|rcsb pdb:4Y8I|rcsb pdb:4Y8J|rcsb pdb:4Y8K|rcsb pdb:4Y8L|rcsb pdb:4Y8M|rcsb pdb:4Y8N|rcsb pdb:4Y8O|rcsb pdb:4Y8P|rcsb pdb:4Y8Q|rcsb pdb:4Y8R|rcsb pdb:4Y8S|rcsb pdb:5FG7|rcsb pdb:5FG9|rcsb pdb:5FGA|rcsb pdb:4YA7|rcsb pdb:4YA9|rcsb pdb:4Z1L|rcsb pdb:5A5B|rcsb pdb:5AHJ|rcsb pdb:5BOU|rcsb pdb:5BXL|rcsb pdb:5BXN|rcsb pdb:5CGF|rcsb pdb:5CGG|rcsb pdb:5CGH|rcsb pdb:5CGI|rcsb pdb:5CZ4|rcsb pdb:5CZ5|rcsb pdb:5CZ6|rcsb pdb:5CZ7|rcsb pdb:5CZ8|rcsb pdb:5CZ9|rcsb pdb:5CZA|rcsb pdb:5D0S|rcsb pdb:5D0T|rcsb pdb:5D0V|rcsb pdb:5D0W|rcsb pdb:5D0X|rcsb pdb:5D0Z|rcsb pdb:5DKI|rcsb pdb:5DKJ|rcsb pdb:5FGD|rcsb pdb:3HYE|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:3MG0|rcsb pdb:3MG4|rcsb pdb:3MG6|rcsb pdb:3MG7|rcsb pdb:3MG8|rcsb pdb:3NZJ|rcsb pdb:3NZW|rcsb pdb:3NZX|rcsb pdb:3OEU|rcsb pdb:3OEV|rcsb pdb:3OKJ|rcsb pdb:3SDI|rcsb pdb:3SDK|rcsb pdb:3SHJ|rcsb pdb:3TDD|rcsb pdb:3UN4|rcsb pdb:3UN8|rcsb pdb:3WXR|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:4EU2|rcsb pdb:4FZC|rcsb pdb:4FZG|rcsb pdb:4G4S|rcsb pdb:4GK7|rcsb pdb:4HNP|rcsb pdb:4HRC|rcsb pdb:4HRD|rcsb pdb:4INR|rcsb pdb:4INT|rcsb pdb:4INU|rcsb pdb:4J70|rcsb pdb:4JSQ|rcsb pdb:4JSU|rcsb pdb:4JT0|rcsb pdb:4LQI|rcsb pdb:4LTC|rcsb pdb:4NNN|rcsb pdb:4NNW|rcsb pdb:4NO1|rcsb pdb:4NO6|rcsb pdb:4NO8|rcsb pdb:4NO9|rcsb pdb:5FGE|rcsb pdb:5FGF|rcsb pdb:5FGG|rcsb pdb:5FGH|rcsb pdb:5FGI|rcsb pdb:5FHS|rcsb pdb:5JHR|rcsb pdb:5JHS|rcsb pdb:5L52|rcsb pdb:5L54|rcsb pdb:5L55|rcsb pdb:5L5A|rcsb pdb:5L5B|rcsb pdb:5L5D|rcsb pdb:5L5E|rcsb pdb:5L5F|rcsb pdb:5L5H|rcsb pdb:5L5I|rcsb pdb:5L5J|rcsb pdb:5L5O|rcsb pdb:5L5P|rcsb pdb:5L5Q|rcsb pdb:5L5R|rcsb pdb:4Q1S|rcsb pdb:4QBY|rcsb pdb:4QLQ|rcsb pdb:4QLS|rcsb pdb:4QLT|rcsb pdb:4QLU|rcsb pdb:4QLV|rcsb pdb:4QUX|rcsb pdb:4QUY|rcsb pdb:4QV0|rcsb pdb:4QV1|rcsb pdb:4QV3|rcsb pdb:4QV4|rcsb pdb:4QV5|rcsb pdb:4QV6|rcsb pdb:4QV7|rcsb pdb:4QV8|rcsb pdb:4QV9|rcsb pdb:4QVL|ensemblfungi:YMR314W(gene)|ensemblfungi:YMR314W_mRNA(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0042175"(nuclear outer membrane-endoplasmic reticulum membrane network)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR035144|rcsb pdb:1FNT|rcsb pdb:1G0U|rcsb pdb:1G65|rcsb pdb:1JD2|rcsb pdb:1RYP|rcsb pdb:1Z7Q|rcsb pdb:2F16|rcsb pdb:2FAK|rcsb pdb:2GPL|rcsb pdb:2ZCY|rcsb pdb:3BDM|rcsb pdb:3D29|rcsb pdb:3DY3|rcsb pdb:3DY4|rcsb pdb:3E47|rcsb pdb:3GPJ|rcsb pdb:3GPT|rcsb pdb:3GPW|rcsb pdb:4QVM|rcsb pdb:4QVN|rcsb pdb:4QVP|rcsb pdb:4QVQ|rcsb pdb:4QVV|rcsb pdb:4QVW|rcsb pdb:4QVY|rcsb pdb:4QW0|rcsb pdb:4QW1|rcsb pdb:4QW3|rcsb pdb:4QW4|rcsb pdb:4QW5|rcsb pdb:4QW6|rcsb pdb:4QW7|rcsb pdb:4QWF|rcsb pdb:4QWG|rcsb pdb:4QWI|rcsb pdb:4QWJ|rcsb pdb:4QWK|rcsb pdb:4QWL|rcsb pdb:4QWR|rcsb pdb:4QWS|rcsb pdb:4QWU|rcsb pdb:4QWX|rcsb pdb:4QXJ|rcsb pdb:4QZ0|rcsb pdb:4QZ1|rcsb pdb:4QZ2|rcsb pdb:4QZ3|rcsb pdb:4QZ4|rcsb pdb:4QZ5|rcsb pdb:4QZ6|rcsb pdb:4QZ7|rcsb pdb:4QZW|rcsb pdb:4QZX|rcsb pdb:4QZZ|rcsb pdb:4R00|rcsb pdb:4R02|rcsb pdb:4R17|rcsb pdb:4R18|rcsb pdb:4RUR|rcsb pdb:4V7O|rcsb pdb:4X6Z|rcsb pdb:4Y69|rcsb pdb:4Y6A|rcsb pdb:4Y6V|rcsb pdb:4Y6Z|rcsb pdb:4Y70|rcsb pdb:4Y74|rcsb pdb:4Y75|rcsb pdb:4Y77|rcsb pdb:4Y78|rcsb pdb:4Y7W|rcsb pdb:5LTT|rcsb pdb:5M2B|rcsb pdb:5MP9|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5NIF|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6G7F|rcsb pdb:6G8M|rcsb pdb:6G8N|rcsb pdb:6GOP|rcsb pdb:6H39|rcsb pdb:6HTB|rcsb pdb:6HTC|rcsb pdb:6HTD|rcsb pdb:6HTP|rcsb pdb:6HTR|rcsb pdb:6HUB|rcsb pdb:6HUC|rcsb pdb:6HUQ|rcsb pdb:6HUU|rcsb pdb:6HUV|rcsb pdb:6HV3|rcsb pdb:6HV4|rcsb pdb:6HV5|rcsb pdb:6HV7|rcsb pdb:6HVA|rcsb pdb:6HVR|rcsb pdb:6HVS|rcsb pdb:6HVT|rcsb pdb:6HVU|rcsb pdb:6HVV|rcsb pdb:5L5S|rcsb pdb:5L5T|rcsb pdb:5L5U|rcsb pdb:5L5V|rcsb pdb:5L5W|rcsb pdb:5L5X|rcsb pdb:5L5Y|rcsb pdb:5L5Z|rcsb pdb:5L60|rcsb pdb:5L61|rcsb pdb:5L62|rcsb pdb:5L63|rcsb pdb:5L64|rcsb pdb:5L65|rcsb pdb:5L66|rcsb pdb:5L67|rcsb pdb:5L68|rcsb pdb:5L69|rcsb pdb:5L6A|rcsb pdb:5L6B|rcsb pdb:5L6C|rcsb pdb:5LAI|rcsb pdb:5LAJ|rcsb pdb:6HVW|rcsb pdb:6HVX|rcsb pdb:6HVY|rcsb pdb:6HW0|rcsb pdb:6HW3|rcsb pdb:6HW4|rcsb pdb:6HW5|rcsb pdb:6HW6|rcsb pdb:6HW7|rcsb pdb:6HW8|rcsb pdb:6HW9|rcsb pdb:6HWA|rcsb pdb:6HWB|rcsb pdb:6HWC|rcsb pdb:6HWD|rcsb pdb:6HWE|rcsb pdb:6HWF|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2X|rcsb pdb:6J30|rcsb pdb:6ZOU|rcsb pdb:6ZP6|rcsb pdb:6ZP8|rcsb pdb:7LS5|rcsb pdb:7LS6|rcsb pdb:7LSX|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|rcsb pdb:6J2Q|refseq:NP_014045.1|sgd:S000004931|mint:P40302|dip:DIP-1528N|sgd:YMR314W(identity)	-	-	crc64:C43CBCC1C6B9E39E	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:XBdXA9tE5Tk5Pn7mO+RIKrlqhEM9606	rogid:C9GPb0JAklkBz0t/YYqRMNEiQss559292	intact-crc:E5747AB6B74F91A0|rigid:7wBQ45RgYl7SXSUSonM+ak+4HdU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40302	uniprotkb:Q14566	intact:EBI-13955|ensemblfungi:YMR314W|uniprotkb:D6W0E1	intact:EBI-374900|uniprotkb:Q13504|uniprotkb:Q99859|uniprotkb:B2R6H2|ensembl:ENSP00000264156	psi-mi:psa6_yeast(display_long)|uniprotkb:PRE5(gene name)|psi-mi:PRE5(display_short)|uniprotkb:YMR314W(locus name)|uniprotkb:YM9924.06(orf name)|uniprotkb:Proteasome component PRE5(gene name synonym)|uniprotkb:Macropain subunit PRE5(gene name synonym)|uniprotkb:Proteinase YSCE subunit PRE5(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit PRE5(gene name synonym)	psi-mi:mcm6_human(display_long)|uniprotkb:MCM6(gene name)|psi-mi:MCM6(display_short)|uniprotkb:p105MCM(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11530560|imex:IM-24995-861	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:4Y8T|rcsb pdb:4Y8U|rcsb pdb:4Y9Y|rcsb pdb:4Y9Z|rcsb pdb:4YA0|rcsb pdb:4YA1|rcsb pdb:4YA2|rcsb pdb:4YA3|rcsb pdb:4YA4|rcsb pdb:4YA5|rcsb pdb:4Y7X|rcsb pdb:4Y7Y|rcsb pdb:4Y80|rcsb pdb:4Y81|rcsb pdb:4Y82|rcsb pdb:4Y84|rcsb pdb:4Y8G|rcsb pdb:4Y8H|rcsb pdb:4Y8I|rcsb pdb:4Y8J|rcsb pdb:4Y8K|rcsb pdb:4Y8L|rcsb pdb:4Y8M|rcsb pdb:4Y8N|rcsb pdb:4Y8O|rcsb pdb:4Y8P|rcsb pdb:4Y8Q|rcsb pdb:4Y8R|rcsb pdb:4Y8S|rcsb pdb:5FG7|rcsb pdb:5FG9|rcsb pdb:5FGA|rcsb pdb:4YA7|rcsb pdb:4YA9|rcsb pdb:4Z1L|rcsb pdb:5A5B|rcsb pdb:5AHJ|rcsb pdb:5BOU|rcsb pdb:5BXL|rcsb pdb:5BXN|rcsb pdb:5CGF|rcsb pdb:5CGG|rcsb pdb:5CGH|rcsb pdb:5CGI|rcsb pdb:5CZ4|rcsb pdb:5CZ5|rcsb pdb:5CZ6|rcsb pdb:5CZ7|rcsb pdb:5CZ8|rcsb pdb:5CZ9|rcsb pdb:5CZA|rcsb pdb:5D0S|rcsb pdb:5D0T|rcsb pdb:5D0V|rcsb pdb:5D0W|rcsb pdb:5D0X|rcsb pdb:5D0Z|rcsb pdb:5DKI|rcsb pdb:5DKJ|rcsb pdb:5FGD|rcsb pdb:3HYE|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:3MG0|rcsb pdb:3MG4|rcsb pdb:3MG6|rcsb pdb:3MG7|rcsb pdb:3MG8|rcsb pdb:3NZJ|rcsb pdb:3NZW|rcsb pdb:3NZX|rcsb pdb:3OEU|rcsb pdb:3OEV|rcsb pdb:3OKJ|rcsb pdb:3SDI|rcsb pdb:3SDK|rcsb pdb:3SHJ|rcsb pdb:3TDD|rcsb pdb:3UN4|rcsb pdb:3UN8|rcsb pdb:3WXR|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:4EU2|rcsb pdb:4FZC|rcsb pdb:4FZG|rcsb pdb:4G4S|rcsb pdb:4GK7|rcsb pdb:4HNP|rcsb pdb:4HRC|rcsb pdb:4HRD|rcsb pdb:4INR|rcsb pdb:4INT|rcsb pdb:4INU|rcsb pdb:4J70|rcsb pdb:4JSQ|rcsb pdb:4JSU|rcsb pdb:4JT0|rcsb pdb:4LQI|rcsb pdb:4LTC|rcsb pdb:4NNN|rcsb pdb:4NNW|rcsb pdb:4NO1|rcsb pdb:4NO6|rcsb pdb:4NO8|rcsb pdb:4NO9|rcsb pdb:5FGE|rcsb pdb:5FGF|rcsb pdb:5FGG|rcsb pdb:5FGH|rcsb pdb:5FGI|rcsb pdb:5FHS|rcsb pdb:5JHR|rcsb pdb:5JHS|rcsb pdb:5L52|rcsb pdb:5L54|rcsb pdb:5L55|rcsb pdb:5L5A|rcsb pdb:5L5B|rcsb pdb:5L5D|rcsb pdb:5L5E|rcsb pdb:5L5F|rcsb pdb:5L5H|rcsb pdb:5L5I|rcsb pdb:5L5J|rcsb pdb:5L5O|rcsb pdb:5L5P|rcsb pdb:5L5Q|rcsb pdb:5L5R|rcsb pdb:4Q1S|rcsb pdb:4QBY|rcsb pdb:4QLQ|rcsb pdb:4QLS|rcsb pdb:4QLT|rcsb pdb:4QLU|rcsb pdb:4QLV|rcsb pdb:4QUX|rcsb pdb:4QUY|rcsb pdb:4QV0|rcsb pdb:4QV1|rcsb pdb:4QV3|rcsb pdb:4QV4|rcsb pdb:4QV5|rcsb pdb:4QV6|rcsb pdb:4QV7|rcsb pdb:4QV8|rcsb pdb:4QV9|rcsb pdb:4QVL|ensemblfungi:YMR314W(gene)|ensemblfungi:YMR314W_mRNA(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0042175"(nuclear outer membrane-endoplasmic reticulum membrane network)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR035144|rcsb pdb:1FNT|rcsb pdb:1G0U|rcsb pdb:1G65|rcsb pdb:1JD2|rcsb pdb:1RYP|rcsb pdb:1Z7Q|rcsb pdb:2F16|rcsb pdb:2FAK|rcsb pdb:2GPL|rcsb pdb:2ZCY|rcsb pdb:3BDM|rcsb pdb:3D29|rcsb pdb:3DY3|rcsb pdb:3DY4|rcsb pdb:3E47|rcsb pdb:3GPJ|rcsb pdb:3GPT|rcsb pdb:3GPW|rcsb pdb:4QVM|rcsb pdb:4QVN|rcsb pdb:4QVP|rcsb pdb:4QVQ|rcsb pdb:4QVV|rcsb pdb:4QVW|rcsb pdb:4QVY|rcsb pdb:4QW0|rcsb pdb:4QW1|rcsb pdb:4QW3|rcsb pdb:4QW4|rcsb pdb:4QW5|rcsb pdb:4QW6|rcsb pdb:4QW7|rcsb pdb:4QWF|rcsb pdb:4QWG|rcsb pdb:4QWI|rcsb pdb:4QWJ|rcsb pdb:4QWK|rcsb pdb:4QWL|rcsb pdb:4QWR|rcsb pdb:4QWS|rcsb pdb:4QWU|rcsb pdb:4QWX|rcsb pdb:4QXJ|rcsb pdb:4QZ0|rcsb pdb:4QZ1|rcsb pdb:4QZ2|rcsb pdb:4QZ3|rcsb pdb:4QZ4|rcsb pdb:4QZ5|rcsb pdb:4QZ6|rcsb pdb:4QZ7|rcsb pdb:4QZW|rcsb pdb:4QZX|rcsb pdb:4QZZ|rcsb pdb:4R00|rcsb pdb:4R02|rcsb pdb:4R17|rcsb pdb:4R18|rcsb pdb:4RUR|rcsb pdb:4V7O|rcsb pdb:4X6Z|rcsb pdb:4Y69|rcsb pdb:4Y6A|rcsb pdb:4Y6V|rcsb pdb:4Y6Z|rcsb pdb:4Y70|rcsb pdb:4Y74|rcsb pdb:4Y75|rcsb pdb:4Y77|rcsb pdb:4Y78|rcsb pdb:4Y7W|rcsb pdb:5LTT|rcsb pdb:5M2B|rcsb pdb:5MP9|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5NIF|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6G7F|rcsb pdb:6G8M|rcsb pdb:6G8N|rcsb pdb:6GOP|rcsb pdb:6H39|rcsb pdb:6HTB|rcsb pdb:6HTC|rcsb pdb:6HTD|rcsb pdb:6HTP|rcsb pdb:6HTR|rcsb pdb:6HUB|rcsb pdb:6HUC|rcsb pdb:6HUQ|rcsb pdb:6HUU|rcsb pdb:6HUV|rcsb pdb:6HV3|rcsb pdb:6HV4|rcsb pdb:6HV5|rcsb pdb:6HV7|rcsb pdb:6HVA|rcsb pdb:6HVR|rcsb pdb:6HVS|rcsb pdb:6HVT|rcsb pdb:6HVU|rcsb pdb:6HVV|rcsb pdb:5L5S|rcsb pdb:5L5T|rcsb pdb:5L5U|rcsb pdb:5L5V|rcsb pdb:5L5W|rcsb pdb:5L5X|rcsb pdb:5L5Y|rcsb pdb:5L5Z|rcsb pdb:5L60|rcsb pdb:5L61|rcsb pdb:5L62|rcsb pdb:5L63|rcsb pdb:5L64|rcsb pdb:5L65|rcsb pdb:5L66|rcsb pdb:5L67|rcsb pdb:5L68|rcsb pdb:5L69|rcsb pdb:5L6A|rcsb pdb:5L6B|rcsb pdb:5L6C|rcsb pdb:5LAI|rcsb pdb:5LAJ|rcsb pdb:6HVW|rcsb pdb:6HVX|rcsb pdb:6HVY|rcsb pdb:6HW0|rcsb pdb:6HW3|rcsb pdb:6HW4|rcsb pdb:6HW5|rcsb pdb:6HW6|rcsb pdb:6HW7|rcsb pdb:6HW8|rcsb pdb:6HW9|rcsb pdb:6HWA|rcsb pdb:6HWB|rcsb pdb:6HWC|rcsb pdb:6HWD|rcsb pdb:6HWE|rcsb pdb:6HWF|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2X|rcsb pdb:6J30|rcsb pdb:6ZOU|rcsb pdb:6ZP6|rcsb pdb:6ZP8|rcsb pdb:7LS5|rcsb pdb:7LS6|rcsb pdb:7LSX|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|rcsb pdb:6J2Q|refseq:NP_014045.1|sgd:S000004931|mint:P40302|dip:DIP-1528N|sgd:YMR314W(identity)	ensembl:ENST00000264156(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0042555"(MCM complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902969"(mitotic DNA replication)|ensembl:ENSG00000076003(gene)|reactome:R-HSA-68962|reactome:R-HSA-69052|interpro:IPR008049(MCM protein 6)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041024|interpro:IPR041562|interpro:IPR001208(MCM)|mint:Q14566|rcsb pdb:2KLQ|rcsb pdb:2LE8|rcsb pdb:6XTX|rcsb pdb:6XTY|reactome:R-HSA-176187|reactome:R-HSA-176974|reactome:R-HSA-68867|reactome:R-HSA-68949|refseq:NP_005906.2|dip:DIP-31727N|entrezgene/locuslink:4175(identity)	-	crc64:C43CBCC1C6B9E39E	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:C9GPb0JAklkBz0t/YYqRMNEiQss559292	rogid:gVpEwgfSwwxvP2T2CvCzIukthY49606	intact-crc:9E4DAC7C62C22332|rigid:ka1v5tXFyE92Gheko7mHscWzz+U	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q13137	uniprotkb:P40302	intact:EBI-739580|uniprotkb:B4DDC4|uniprotkb:E7ENK0|uniprotkb:Q53FQ5|uniprotkb:Q53HB5|uniprotkb:Q6IBN9|uniprotkb:Q9BTF7|uniprotkb:B2RBT0|ensembl:ENSP00000258947|uniprotkb:B4E0C0|uniprotkb:E7ETP5|uniprotkb:B4DDT4|uniprotkb:B4DP36|uniprotkb:E9PBE5	intact:EBI-13955|ensemblfungi:YMR314W|uniprotkb:D6W0E1	psi-mi:caco2_human(display_long)|uniprotkb:CALCOCO2(gene name)|psi-mi:CALCOCO2(display_short)|uniprotkb:NDP52(gene name synonym)|uniprotkb:Nuclear domain 10 protein NDP52(gene name synonym)|uniprotkb:Antigen nuclear dot 52 kDa protein(gene name synonym)|uniprotkb:Nuclear dot protein 52(gene name synonym)	psi-mi:psa6_yeast(display_long)|uniprotkb:PRE5(gene name)|psi-mi:PRE5(display_short)|uniprotkb:YMR314W(locus name)|uniprotkb:YM9924.06(orf name)|uniprotkb:Proteasome component PRE5(gene name synonym)|uniprotkb:Macropain subunit PRE5(gene name synonym)|uniprotkb:Proteinase YSCE subunit PRE5(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit PRE5(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11530551|imex:IM-24995-860	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001248319.1|refseq:NP_001248320.1|refseq:NP_001248322.1|refseq:NP_005822.1|ensembl:ENSG00000136436(gene)|ensembl:ENST00000258947(transcript)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016032"(viral process)|go:"GO:0016605"(PML body)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0098792"(xenophagy)|go:"GO:1901098"(positive regulation of autophagosome maturation)|interpro:IPR041611|interpro:IPR041641|mint:Q13137|rcsb pdb:2MXP|rcsb pdb:3VVV|rcsb pdb:3VVW|rcsb pdb:4GXL|rcsb pdb:4HAN|rcsb pdb:4XKL|rcsb pdb:5AAQ|rcsb pdb:5Z7A|rcsb pdb:5Z7L|refseq:NP_001248324.1|dip:DIP-57534N|entrezgene/locuslink:10241(identity)	rcsb pdb:4Y8T|rcsb pdb:4Y8U|rcsb pdb:4Y9Y|rcsb pdb:4Y9Z|rcsb pdb:4YA0|rcsb pdb:4YA1|rcsb pdb:4YA2|rcsb pdb:4YA3|rcsb pdb:4YA4|rcsb pdb:4YA5|rcsb pdb:4Y7X|rcsb pdb:4Y7Y|rcsb pdb:4Y80|rcsb pdb:4Y81|rcsb pdb:4Y82|rcsb pdb:4Y84|rcsb pdb:4Y8G|rcsb pdb:4Y8H|rcsb pdb:4Y8I|rcsb pdb:4Y8J|rcsb pdb:4Y8K|rcsb pdb:4Y8L|rcsb pdb:4Y8M|rcsb pdb:4Y8N|rcsb pdb:4Y8O|rcsb pdb:4Y8P|rcsb pdb:4Y8Q|rcsb pdb:4Y8R|rcsb pdb:4Y8S|rcsb pdb:5FG7|rcsb pdb:5FG9|rcsb pdb:5FGA|rcsb pdb:4YA7|rcsb pdb:4YA9|rcsb pdb:4Z1L|rcsb pdb:5A5B|rcsb pdb:5AHJ|rcsb pdb:5BOU|rcsb pdb:5BXL|rcsb pdb:5BXN|rcsb pdb:5CGF|rcsb pdb:5CGG|rcsb pdb:5CGH|rcsb pdb:5CGI|rcsb pdb:5CZ4|rcsb pdb:5CZ5|rcsb pdb:5CZ6|rcsb pdb:5CZ7|rcsb pdb:5CZ8|rcsb pdb:5CZ9|rcsb pdb:5CZA|rcsb pdb:5D0S|rcsb pdb:5D0T|rcsb pdb:5D0V|rcsb pdb:5D0W|rcsb pdb:5D0X|rcsb pdb:5D0Z|rcsb pdb:5DKI|rcsb pdb:5DKJ|rcsb pdb:5FGD|rcsb pdb:3HYE|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:3MG0|rcsb pdb:3MG4|rcsb pdb:3MG6|rcsb pdb:3MG7|rcsb pdb:3MG8|rcsb pdb:3NZJ|rcsb pdb:3NZW|rcsb pdb:3NZX|rcsb pdb:3OEU|rcsb pdb:3OEV|rcsb pdb:3OKJ|rcsb pdb:3SDI|rcsb pdb:3SDK|rcsb pdb:3SHJ|rcsb pdb:3TDD|rcsb pdb:3UN4|rcsb pdb:3UN8|rcsb pdb:3WXR|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:4EU2|rcsb pdb:4FZC|rcsb pdb:4FZG|rcsb pdb:4G4S|rcsb pdb:4GK7|rcsb pdb:4HNP|rcsb pdb:4HRC|rcsb pdb:4HRD|rcsb pdb:4INR|rcsb pdb:4INT|rcsb pdb:4INU|rcsb pdb:4J70|rcsb pdb:4JSQ|rcsb pdb:4JSU|rcsb pdb:4JT0|rcsb pdb:4LQI|rcsb pdb:4LTC|rcsb pdb:4NNN|rcsb pdb:4NNW|rcsb pdb:4NO1|rcsb pdb:4NO6|rcsb pdb:4NO8|rcsb pdb:4NO9|rcsb pdb:5FGE|rcsb pdb:5FGF|rcsb pdb:5FGG|rcsb pdb:5FGH|rcsb pdb:5FGI|rcsb pdb:5FHS|rcsb pdb:5JHR|rcsb pdb:5JHS|rcsb pdb:5L52|rcsb pdb:5L54|rcsb pdb:5L55|rcsb pdb:5L5A|rcsb pdb:5L5B|rcsb pdb:5L5D|rcsb pdb:5L5E|rcsb pdb:5L5F|rcsb pdb:5L5H|rcsb pdb:5L5I|rcsb pdb:5L5J|rcsb pdb:5L5O|rcsb pdb:5L5P|rcsb pdb:5L5Q|rcsb pdb:5L5R|rcsb pdb:4Q1S|rcsb pdb:4QBY|rcsb pdb:4QLQ|rcsb pdb:4QLS|rcsb pdb:4QLT|rcsb pdb:4QLU|rcsb pdb:4QLV|rcsb pdb:4QUX|rcsb pdb:4QUY|rcsb pdb:4QV0|rcsb pdb:4QV1|rcsb pdb:4QV3|rcsb pdb:4QV4|rcsb pdb:4QV5|rcsb pdb:4QV6|rcsb pdb:4QV7|rcsb pdb:4QV8|rcsb pdb:4QV9|rcsb pdb:4QVL|ensemblfungi:YMR314W(gene)|ensemblfungi:YMR314W_mRNA(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0042175"(nuclear outer membrane-endoplasmic reticulum membrane network)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR035144|rcsb pdb:1FNT|rcsb pdb:1G0U|rcsb pdb:1G65|rcsb pdb:1JD2|rcsb pdb:1RYP|rcsb pdb:1Z7Q|rcsb pdb:2F16|rcsb pdb:2FAK|rcsb pdb:2GPL|rcsb pdb:2ZCY|rcsb pdb:3BDM|rcsb pdb:3D29|rcsb pdb:3DY3|rcsb pdb:3DY4|rcsb pdb:3E47|rcsb pdb:3GPJ|rcsb pdb:3GPT|rcsb pdb:3GPW|rcsb pdb:4QVM|rcsb pdb:4QVN|rcsb pdb:4QVP|rcsb pdb:4QVQ|rcsb pdb:4QVV|rcsb pdb:4QVW|rcsb pdb:4QVY|rcsb pdb:4QW0|rcsb pdb:4QW1|rcsb pdb:4QW3|rcsb pdb:4QW4|rcsb pdb:4QW5|rcsb pdb:4QW6|rcsb pdb:4QW7|rcsb pdb:4QWF|rcsb pdb:4QWG|rcsb pdb:4QWI|rcsb pdb:4QWJ|rcsb pdb:4QWK|rcsb pdb:4QWL|rcsb pdb:4QWR|rcsb pdb:4QWS|rcsb pdb:4QWU|rcsb pdb:4QWX|rcsb pdb:4QXJ|rcsb pdb:4QZ0|rcsb pdb:4QZ1|rcsb pdb:4QZ2|rcsb pdb:4QZ3|rcsb pdb:4QZ4|rcsb pdb:4QZ5|rcsb pdb:4QZ6|rcsb pdb:4QZ7|rcsb pdb:4QZW|rcsb pdb:4QZX|rcsb pdb:4QZZ|rcsb pdb:4R00|rcsb pdb:4R02|rcsb pdb:4R17|rcsb pdb:4R18|rcsb pdb:4RUR|rcsb pdb:4V7O|rcsb pdb:4X6Z|rcsb pdb:4Y69|rcsb pdb:4Y6A|rcsb pdb:4Y6V|rcsb pdb:4Y6Z|rcsb pdb:4Y70|rcsb pdb:4Y74|rcsb pdb:4Y75|rcsb pdb:4Y77|rcsb pdb:4Y78|rcsb pdb:4Y7W|rcsb pdb:5LTT|rcsb pdb:5M2B|rcsb pdb:5MP9|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5NIF|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6G7F|rcsb pdb:6G8M|rcsb pdb:6G8N|rcsb pdb:6GOP|rcsb pdb:6H39|rcsb pdb:6HTB|rcsb pdb:6HTC|rcsb pdb:6HTD|rcsb pdb:6HTP|rcsb pdb:6HTR|rcsb pdb:6HUB|rcsb pdb:6HUC|rcsb pdb:6HUQ|rcsb pdb:6HUU|rcsb pdb:6HUV|rcsb pdb:6HV3|rcsb pdb:6HV4|rcsb pdb:6HV5|rcsb pdb:6HV7|rcsb pdb:6HVA|rcsb pdb:6HVR|rcsb pdb:6HVS|rcsb pdb:6HVT|rcsb pdb:6HVU|rcsb pdb:6HVV|rcsb pdb:5L5S|rcsb pdb:5L5T|rcsb pdb:5L5U|rcsb pdb:5L5V|rcsb pdb:5L5W|rcsb pdb:5L5X|rcsb pdb:5L5Y|rcsb pdb:5L5Z|rcsb pdb:5L60|rcsb pdb:5L61|rcsb pdb:5L62|rcsb pdb:5L63|rcsb pdb:5L64|rcsb pdb:5L65|rcsb pdb:5L66|rcsb pdb:5L67|rcsb pdb:5L68|rcsb pdb:5L69|rcsb pdb:5L6A|rcsb pdb:5L6B|rcsb pdb:5L6C|rcsb pdb:5LAI|rcsb pdb:5LAJ|rcsb pdb:6HVW|rcsb pdb:6HVX|rcsb pdb:6HVY|rcsb pdb:6HW0|rcsb pdb:6HW3|rcsb pdb:6HW4|rcsb pdb:6HW5|rcsb pdb:6HW6|rcsb pdb:6HW7|rcsb pdb:6HW8|rcsb pdb:6HW9|rcsb pdb:6HWA|rcsb pdb:6HWB|rcsb pdb:6HWC|rcsb pdb:6HWD|rcsb pdb:6HWE|rcsb pdb:6HWF|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2X|rcsb pdb:6J30|rcsb pdb:6ZOU|rcsb pdb:6ZP6|rcsb pdb:6ZP8|rcsb pdb:7LS5|rcsb pdb:7LS6|rcsb pdb:7LSX|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|rcsb pdb:6J2Q|refseq:NP_014045.1|sgd:S000004931|mint:P40302|dip:DIP-1528N|sgd:YMR314W(identity)	-	crc64:609B121DA1A9DCB8	crc64:C43CBCC1C6B9E39E	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:N/GPJUGBK+Dh5Cg+csmafphuo9M9606	rogid:C9GPb0JAklkBz0t/YYqRMNEiQss559292	intact-crc:0DC8059525C4BF81|rigid:ZfDt5eZYjTzVB9Ttb5Mz5Rmtrd4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40302	uniprotkb:P14373	intact:EBI-13955|ensemblfungi:YMR314W|uniprotkb:D6W0E1	intact:EBI-719493|uniprotkb:A2BE15|uniprotkb:Q5RJA8|uniprotkb:Q5ST26|uniprotkb:Q6LA73|uniprotkb:Q6NXR9|uniprotkb:Q9BZY6|uniprotkb:Q9UJL3|ensembl:ENSP00000383555|ensembl:ENSP00000392787|ensembl:ENSP00000405229|ensembl:ENSP00000414793|ensembl:ENSP00000366404	psi-mi:psa6_yeast(display_long)|uniprotkb:PRE5(gene name)|psi-mi:PRE5(display_short)|uniprotkb:YMR314W(locus name)|uniprotkb:YM9924.06(orf name)|uniprotkb:Proteasome component PRE5(gene name synonym)|uniprotkb:Macropain subunit PRE5(gene name synonym)|uniprotkb:Proteinase YSCE subunit PRE5(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit PRE5(gene name synonym)	psi-mi:tri27_human(display_long)|uniprotkb:TRIM27(gene name)|psi-mi:TRIM27(display_short)|uniprotkb:RNF76(gene name synonym)|uniprotkb:RFP(gene name synonym)|uniprotkb:Ret finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 27(gene name synonym)|uniprotkb:RING finger protein 76(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM27(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11530542|imex:IM-24995-859	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:4Y8T|rcsb pdb:4Y8U|rcsb pdb:4Y9Y|rcsb pdb:4Y9Z|rcsb pdb:4YA0|rcsb pdb:4YA1|rcsb pdb:4YA2|rcsb pdb:4YA3|rcsb pdb:4YA4|rcsb pdb:4YA5|rcsb pdb:4Y7X|rcsb pdb:4Y7Y|rcsb pdb:4Y80|rcsb pdb:4Y81|rcsb pdb:4Y82|rcsb pdb:4Y84|rcsb pdb:4Y8G|rcsb pdb:4Y8H|rcsb pdb:4Y8I|rcsb pdb:4Y8J|rcsb pdb:4Y8K|rcsb pdb:4Y8L|rcsb pdb:4Y8M|rcsb pdb:4Y8N|rcsb pdb:4Y8O|rcsb pdb:4Y8P|rcsb pdb:4Y8Q|rcsb pdb:4Y8R|rcsb pdb:4Y8S|rcsb pdb:5FG7|rcsb pdb:5FG9|rcsb pdb:5FGA|rcsb pdb:4YA7|rcsb pdb:4YA9|rcsb pdb:4Z1L|rcsb pdb:5A5B|rcsb pdb:5AHJ|rcsb pdb:5BOU|rcsb pdb:5BXL|rcsb pdb:5BXN|rcsb pdb:5CGF|rcsb pdb:5CGG|rcsb pdb:5CGH|rcsb pdb:5CGI|rcsb pdb:5CZ4|rcsb pdb:5CZ5|rcsb pdb:5CZ6|rcsb pdb:5CZ7|rcsb pdb:5CZ8|rcsb pdb:5CZ9|rcsb pdb:5CZA|rcsb pdb:5D0S|rcsb pdb:5D0T|rcsb pdb:5D0V|rcsb pdb:5D0W|rcsb pdb:5D0X|rcsb pdb:5D0Z|rcsb pdb:5DKI|rcsb pdb:5DKJ|rcsb pdb:5FGD|rcsb pdb:3HYE|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:3MG0|rcsb pdb:3MG4|rcsb pdb:3MG6|rcsb pdb:3MG7|rcsb pdb:3MG8|rcsb pdb:3NZJ|rcsb pdb:3NZW|rcsb pdb:3NZX|rcsb pdb:3OEU|rcsb pdb:3OEV|rcsb pdb:3OKJ|rcsb pdb:3SDI|rcsb pdb:3SDK|rcsb pdb:3SHJ|rcsb pdb:3TDD|rcsb pdb:3UN4|rcsb pdb:3UN8|rcsb pdb:3WXR|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:4EU2|rcsb pdb:4FZC|rcsb pdb:4FZG|rcsb pdb:4G4S|rcsb pdb:4GK7|rcsb pdb:4HNP|rcsb pdb:4HRC|rcsb pdb:4HRD|rcsb pdb:4INR|rcsb pdb:4INT|rcsb pdb:4INU|rcsb pdb:4J70|rcsb pdb:4JSQ|rcsb pdb:4JSU|rcsb pdb:4JT0|rcsb pdb:4LQI|rcsb pdb:4LTC|rcsb pdb:4NNN|rcsb pdb:4NNW|rcsb pdb:4NO1|rcsb pdb:4NO6|rcsb pdb:4NO8|rcsb pdb:4NO9|rcsb pdb:5FGE|rcsb pdb:5FGF|rcsb pdb:5FGG|rcsb pdb:5FGH|rcsb pdb:5FGI|rcsb pdb:5FHS|rcsb pdb:5JHR|rcsb pdb:5JHS|rcsb pdb:5L52|rcsb pdb:5L54|rcsb pdb:5L55|rcsb pdb:5L5A|rcsb pdb:5L5B|rcsb pdb:5L5D|rcsb pdb:5L5E|rcsb pdb:5L5F|rcsb pdb:5L5H|rcsb pdb:5L5I|rcsb pdb:5L5J|rcsb pdb:5L5O|rcsb pdb:5L5P|rcsb pdb:5L5Q|rcsb pdb:5L5R|rcsb pdb:4Q1S|rcsb pdb:4QBY|rcsb pdb:4QLQ|rcsb pdb:4QLS|rcsb pdb:4QLT|rcsb pdb:4QLU|rcsb pdb:4QLV|rcsb pdb:4QUX|rcsb pdb:4QUY|rcsb pdb:4QV0|rcsb pdb:4QV1|rcsb pdb:4QV3|rcsb pdb:4QV4|rcsb pdb:4QV5|rcsb pdb:4QV6|rcsb pdb:4QV7|rcsb pdb:4QV8|rcsb pdb:4QV9|rcsb pdb:4QVL|ensemblfungi:YMR314W(gene)|ensemblfungi:YMR314W_mRNA(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0042175"(nuclear outer membrane-endoplasmic reticulum membrane network)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR035144|rcsb pdb:1FNT|rcsb pdb:1G0U|rcsb pdb:1G65|rcsb pdb:1JD2|rcsb pdb:1RYP|rcsb pdb:1Z7Q|rcsb pdb:2F16|rcsb pdb:2FAK|rcsb pdb:2GPL|rcsb pdb:2ZCY|rcsb pdb:3BDM|rcsb pdb:3D29|rcsb pdb:3DY3|rcsb pdb:3DY4|rcsb pdb:3E47|rcsb pdb:3GPJ|rcsb pdb:3GPT|rcsb pdb:3GPW|rcsb pdb:4QVM|rcsb pdb:4QVN|rcsb pdb:4QVP|rcsb pdb:4QVQ|rcsb pdb:4QVV|rcsb pdb:4QVW|rcsb pdb:4QVY|rcsb pdb:4QW0|rcsb pdb:4QW1|rcsb pdb:4QW3|rcsb pdb:4QW4|rcsb pdb:4QW5|rcsb pdb:4QW6|rcsb pdb:4QW7|rcsb pdb:4QWF|rcsb pdb:4QWG|rcsb pdb:4QWI|rcsb pdb:4QWJ|rcsb pdb:4QWK|rcsb pdb:4QWL|rcsb pdb:4QWR|rcsb pdb:4QWS|rcsb pdb:4QWU|rcsb pdb:4QWX|rcsb pdb:4QXJ|rcsb pdb:4QZ0|rcsb pdb:4QZ1|rcsb pdb:4QZ2|rcsb pdb:4QZ3|rcsb pdb:4QZ4|rcsb pdb:4QZ5|rcsb pdb:4QZ6|rcsb pdb:4QZ7|rcsb pdb:4QZW|rcsb pdb:4QZX|rcsb pdb:4QZZ|rcsb pdb:4R00|rcsb pdb:4R02|rcsb pdb:4R17|rcsb pdb:4R18|rcsb pdb:4RUR|rcsb pdb:4V7O|rcsb pdb:4X6Z|rcsb pdb:4Y69|rcsb pdb:4Y6A|rcsb pdb:4Y6V|rcsb pdb:4Y6Z|rcsb pdb:4Y70|rcsb pdb:4Y74|rcsb pdb:4Y75|rcsb pdb:4Y77|rcsb pdb:4Y78|rcsb pdb:4Y7W|rcsb pdb:5LTT|rcsb pdb:5M2B|rcsb pdb:5MP9|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5NIF|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6G7F|rcsb pdb:6G8M|rcsb pdb:6G8N|rcsb pdb:6GOP|rcsb pdb:6H39|rcsb pdb:6HTB|rcsb pdb:6HTC|rcsb pdb:6HTD|rcsb pdb:6HTP|rcsb pdb:6HTR|rcsb pdb:6HUB|rcsb pdb:6HUC|rcsb pdb:6HUQ|rcsb pdb:6HUU|rcsb pdb:6HUV|rcsb pdb:6HV3|rcsb pdb:6HV4|rcsb pdb:6HV5|rcsb pdb:6HV7|rcsb pdb:6HVA|rcsb pdb:6HVR|rcsb pdb:6HVS|rcsb pdb:6HVT|rcsb pdb:6HVU|rcsb pdb:6HVV|rcsb pdb:5L5S|rcsb pdb:5L5T|rcsb pdb:5L5U|rcsb pdb:5L5V|rcsb pdb:5L5W|rcsb pdb:5L5X|rcsb pdb:5L5Y|rcsb pdb:5L5Z|rcsb pdb:5L60|rcsb pdb:5L61|rcsb pdb:5L62|rcsb pdb:5L63|rcsb pdb:5L64|rcsb pdb:5L65|rcsb pdb:5L66|rcsb pdb:5L67|rcsb pdb:5L68|rcsb pdb:5L69|rcsb pdb:5L6A|rcsb pdb:5L6B|rcsb pdb:5L6C|rcsb pdb:5LAI|rcsb pdb:5LAJ|rcsb pdb:6HVW|rcsb pdb:6HVX|rcsb pdb:6HVY|rcsb pdb:6HW0|rcsb pdb:6HW3|rcsb pdb:6HW4|rcsb pdb:6HW5|rcsb pdb:6HW6|rcsb pdb:6HW7|rcsb pdb:6HW8|rcsb pdb:6HW9|rcsb pdb:6HWA|rcsb pdb:6HWB|rcsb pdb:6HWC|rcsb pdb:6HWD|rcsb pdb:6HWE|rcsb pdb:6HWF|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2X|rcsb pdb:6J30|rcsb pdb:6ZOU|rcsb pdb:6ZP6|rcsb pdb:6ZP8|rcsb pdb:7LS5|rcsb pdb:7LS6|rcsb pdb:7LSX|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|rcsb pdb:6J2Q|refseq:NP_014045.1|sgd:S000004931|mint:P40302|dip:DIP-1528N|sgd:YMR314W(identity)	refseq:NP_006501.1|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0090281"(negative regulation of calcium ion import)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR020457|interpro:IPR035791|interpro:IPR043136|mint:P14373|reactome:R-HSA-3232142|reactome:R-HSA-9635465|reactome:R-HSA-8948751|ensembl:ENSG00000204713(gene)|ensembl:ENSG00000215641(gene)|ensembl:ENSG00000229006(gene)|ensembl:ENSG00000234495(gene)|ensembl:ENSG00000237071(gene)|ensembl:ENST00000377199(transcript)|ensembl:ENST00000400720(transcript)|ensembl:ENST00000431123(transcript)|ensembl:ENST00000435528(transcript)|ensembl:ENST00000437160(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001650"(fibrillar center)|go:"GO:0002820"(negative regulation of adaptive immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|entrezgene/locuslink:5987(identity)	-	crc64:C43CBCC1C6B9E39E	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:C9GPb0JAklkBz0t/YYqRMNEiQss559292	rogid:dsfH5OUghD8KSaTz1SFw9OYVTK49606	intact-crc:99E0C46CBB6189F5|rigid:NWGPMzOW08lVjEjcmDD50hI80bY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O95073-2	uniprotkb:P40302	intact:EBI-10696047	intact:EBI-13955|ensemblfungi:YMR314W|uniprotkb:D6W0E1	psi-mi:o95073-2(display_long)|uniprotkb:FSBP(gene name)|psi-mi:FSBP(display_short)	psi-mi:psa6_yeast(display_long)|uniprotkb:PRE5(gene name)|psi-mi:PRE5(display_short)|uniprotkb:YMR314W(locus name)|uniprotkb:YM9924.06(orf name)|uniprotkb:Proteasome component PRE5(gene name synonym)|uniprotkb:Macropain subunit PRE5(gene name synonym)|uniprotkb:Proteinase YSCE subunit PRE5(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit PRE5(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11530533|imex:IM-24995-858	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-1059030(isoform-parent)|uniprotkb:O95073-2(isoform-parent)|entrezgene/locuslink:25788(identity)	rcsb pdb:4Y8T|rcsb pdb:4Y8U|rcsb pdb:4Y9Y|rcsb pdb:4Y9Z|rcsb pdb:4YA0|rcsb pdb:4YA1|rcsb pdb:4YA2|rcsb pdb:4YA3|rcsb pdb:4YA4|rcsb pdb:4YA5|rcsb pdb:4Y7X|rcsb pdb:4Y7Y|rcsb pdb:4Y80|rcsb pdb:4Y81|rcsb pdb:4Y82|rcsb pdb:4Y84|rcsb pdb:4Y8G|rcsb pdb:4Y8H|rcsb pdb:4Y8I|rcsb pdb:4Y8J|rcsb pdb:4Y8K|rcsb pdb:4Y8L|rcsb pdb:4Y8M|rcsb pdb:4Y8N|rcsb pdb:4Y8O|rcsb pdb:4Y8P|rcsb pdb:4Y8Q|rcsb pdb:4Y8R|rcsb pdb:4Y8S|rcsb pdb:5FG7|rcsb pdb:5FG9|rcsb pdb:5FGA|rcsb pdb:4YA7|rcsb pdb:4YA9|rcsb pdb:4Z1L|rcsb pdb:5A5B|rcsb pdb:5AHJ|rcsb pdb:5BOU|rcsb pdb:5BXL|rcsb pdb:5BXN|rcsb pdb:5CGF|rcsb pdb:5CGG|rcsb pdb:5CGH|rcsb pdb:5CGI|rcsb pdb:5CZ4|rcsb pdb:5CZ5|rcsb pdb:5CZ6|rcsb pdb:5CZ7|rcsb pdb:5CZ8|rcsb pdb:5CZ9|rcsb pdb:5CZA|rcsb pdb:5D0S|rcsb pdb:5D0T|rcsb pdb:5D0V|rcsb pdb:5D0W|rcsb pdb:5D0X|rcsb pdb:5D0Z|rcsb pdb:5DKI|rcsb pdb:5DKJ|rcsb pdb:5FGD|rcsb pdb:3HYE|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:3MG0|rcsb pdb:3MG4|rcsb pdb:3MG6|rcsb pdb:3MG7|rcsb pdb:3MG8|rcsb pdb:3NZJ|rcsb pdb:3NZW|rcsb pdb:3NZX|rcsb pdb:3OEU|rcsb pdb:3OEV|rcsb pdb:3OKJ|rcsb pdb:3SDI|rcsb pdb:3SDK|rcsb pdb:3SHJ|rcsb pdb:3TDD|rcsb pdb:3UN4|rcsb pdb:3UN8|rcsb pdb:3WXR|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:4EU2|rcsb pdb:4FZC|rcsb pdb:4FZG|rcsb pdb:4G4S|rcsb pdb:4GK7|rcsb pdb:4HNP|rcsb pdb:4HRC|rcsb pdb:4HRD|rcsb pdb:4INR|rcsb pdb:4INT|rcsb pdb:4INU|rcsb pdb:4J70|rcsb pdb:4JSQ|rcsb pdb:4JSU|rcsb pdb:4JT0|rcsb pdb:4LQI|rcsb pdb:4LTC|rcsb pdb:4NNN|rcsb pdb:4NNW|rcsb pdb:4NO1|rcsb pdb:4NO6|rcsb pdb:4NO8|rcsb pdb:4NO9|rcsb pdb:5FGE|rcsb pdb:5FGF|rcsb pdb:5FGG|rcsb pdb:5FGH|rcsb pdb:5FGI|rcsb pdb:5FHS|rcsb pdb:5JHR|rcsb pdb:5JHS|rcsb pdb:5L52|rcsb pdb:5L54|rcsb pdb:5L55|rcsb pdb:5L5A|rcsb pdb:5L5B|rcsb pdb:5L5D|rcsb pdb:5L5E|rcsb pdb:5L5F|rcsb pdb:5L5H|rcsb pdb:5L5I|rcsb pdb:5L5J|rcsb pdb:5L5O|rcsb pdb:5L5P|rcsb pdb:5L5Q|rcsb pdb:5L5R|rcsb pdb:4Q1S|rcsb pdb:4QBY|rcsb pdb:4QLQ|rcsb pdb:4QLS|rcsb pdb:4QLT|rcsb pdb:4QLU|rcsb pdb:4QLV|rcsb pdb:4QUX|rcsb pdb:4QUY|rcsb pdb:4QV0|rcsb pdb:4QV1|rcsb pdb:4QV3|rcsb pdb:4QV4|rcsb pdb:4QV5|rcsb pdb:4QV6|rcsb pdb:4QV7|rcsb pdb:4QV8|rcsb pdb:4QV9|rcsb pdb:4QVL|ensemblfungi:YMR314W(gene)|ensemblfungi:YMR314W_mRNA(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0042175"(nuclear outer membrane-endoplasmic reticulum membrane network)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR035144|rcsb pdb:1FNT|rcsb pdb:1G0U|rcsb pdb:1G65|rcsb pdb:1JD2|rcsb pdb:1RYP|rcsb pdb:1Z7Q|rcsb pdb:2F16|rcsb pdb:2FAK|rcsb pdb:2GPL|rcsb pdb:2ZCY|rcsb pdb:3BDM|rcsb pdb:3D29|rcsb pdb:3DY3|rcsb pdb:3DY4|rcsb pdb:3E47|rcsb pdb:3GPJ|rcsb pdb:3GPT|rcsb pdb:3GPW|rcsb pdb:4QVM|rcsb pdb:4QVN|rcsb pdb:4QVP|rcsb pdb:4QVQ|rcsb pdb:4QVV|rcsb pdb:4QVW|rcsb pdb:4QVY|rcsb pdb:4QW0|rcsb pdb:4QW1|rcsb pdb:4QW3|rcsb pdb:4QW4|rcsb pdb:4QW5|rcsb pdb:4QW6|rcsb pdb:4QW7|rcsb pdb:4QWF|rcsb pdb:4QWG|rcsb pdb:4QWI|rcsb pdb:4QWJ|rcsb pdb:4QWK|rcsb pdb:4QWL|rcsb pdb:4QWR|rcsb pdb:4QWS|rcsb pdb:4QWU|rcsb pdb:4QWX|rcsb pdb:4QXJ|rcsb pdb:4QZ0|rcsb pdb:4QZ1|rcsb pdb:4QZ2|rcsb pdb:4QZ3|rcsb pdb:4QZ4|rcsb pdb:4QZ5|rcsb pdb:4QZ6|rcsb pdb:4QZ7|rcsb pdb:4QZW|rcsb pdb:4QZX|rcsb pdb:4QZZ|rcsb pdb:4R00|rcsb pdb:4R02|rcsb pdb:4R17|rcsb pdb:4R18|rcsb pdb:4RUR|rcsb pdb:4V7O|rcsb pdb:4X6Z|rcsb pdb:4Y69|rcsb pdb:4Y6A|rcsb pdb:4Y6V|rcsb pdb:4Y6Z|rcsb pdb:4Y70|rcsb pdb:4Y74|rcsb pdb:4Y75|rcsb pdb:4Y77|rcsb pdb:4Y78|rcsb pdb:4Y7W|rcsb pdb:5LTT|rcsb pdb:5M2B|rcsb pdb:5MP9|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5NIF|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6G7F|rcsb pdb:6G8M|rcsb pdb:6G8N|rcsb pdb:6GOP|rcsb pdb:6H39|rcsb pdb:6HTB|rcsb pdb:6HTC|rcsb pdb:6HTD|rcsb pdb:6HTP|rcsb pdb:6HTR|rcsb pdb:6HUB|rcsb pdb:6HUC|rcsb pdb:6HUQ|rcsb pdb:6HUU|rcsb pdb:6HUV|rcsb pdb:6HV3|rcsb pdb:6HV4|rcsb pdb:6HV5|rcsb pdb:6HV7|rcsb pdb:6HVA|rcsb pdb:6HVR|rcsb pdb:6HVS|rcsb pdb:6HVT|rcsb pdb:6HVU|rcsb pdb:6HVV|rcsb pdb:5L5S|rcsb pdb:5L5T|rcsb pdb:5L5U|rcsb pdb:5L5V|rcsb pdb:5L5W|rcsb pdb:5L5X|rcsb pdb:5L5Y|rcsb pdb:5L5Z|rcsb pdb:5L60|rcsb pdb:5L61|rcsb pdb:5L62|rcsb pdb:5L63|rcsb pdb:5L64|rcsb pdb:5L65|rcsb pdb:5L66|rcsb pdb:5L67|rcsb pdb:5L68|rcsb pdb:5L69|rcsb pdb:5L6A|rcsb pdb:5L6B|rcsb pdb:5L6C|rcsb pdb:5LAI|rcsb pdb:5LAJ|rcsb pdb:6HVW|rcsb pdb:6HVX|rcsb pdb:6HVY|rcsb pdb:6HW0|rcsb pdb:6HW3|rcsb pdb:6HW4|rcsb pdb:6HW5|rcsb pdb:6HW6|rcsb pdb:6HW7|rcsb pdb:6HW8|rcsb pdb:6HW9|rcsb pdb:6HWA|rcsb pdb:6HWB|rcsb pdb:6HWC|rcsb pdb:6HWD|rcsb pdb:6HWE|rcsb pdb:6HWF|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2X|rcsb pdb:6J30|rcsb pdb:6ZOU|rcsb pdb:6ZP6|rcsb pdb:6ZP8|rcsb pdb:7LS5|rcsb pdb:7LS6|rcsb pdb:7LSX|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|rcsb pdb:6J2Q|refseq:NP_014045.1|sgd:S000004931|mint:P40302|dip:DIP-1528N|sgd:YMR314W(identity)	-	isoform-comment:No experimental confirmation available.	crc64:C43CBCC1C6B9E39E	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:j4ktleFZa7rAjRFENAKAGdAd+Fs9606	rogid:C9GPb0JAklkBz0t/YYqRMNEiQss559292	intact-crc:FE8BB51ACD023F8E|rigid:/4/t9j6pG8UVth1hTqK8+YOMRxc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96CV9-2	uniprotkb:P40302	intact:EBI-9091423|ensembl:ENSP00000368027|ensembl:ENSP00000368040	intact:EBI-13955|ensemblfungi:YMR314W|uniprotkb:D6W0E1	psi-mi:q96cv9-2(display_long)|uniprotkb:E3-14.7K-interacting protein(gene name synonym)|uniprotkb:FIP-2(gene name synonym)|uniprotkb:FIP2(gene name synonym)|uniprotkb:GLC1E(gene name synonym)|uniprotkb:HIP7(gene name synonym)|uniprotkb:HYPL(gene name synonym)|uniprotkb:Huntingtin yeast partner L(gene name synonym)|uniprotkb:Huntingtin-interacting protein 7(gene name synonym)|uniprotkb:Huntingtin-interacting protein L(gene name synonym)|uniprotkb:NEMO-related protein(gene name synonym)|uniprotkb:NRP(gene name synonym)|uniprotkb:Optic neuropathy-inducing protein(gene name synonym)|uniprotkb:Transcription factor IIIA-interacting protein(gene name synonym)|uniprotkb:OPTN(gene name)|psi-mi:OPTN(display_short)	psi-mi:psa6_yeast(display_long)|uniprotkb:PRE5(gene name)|psi-mi:PRE5(display_short)|uniprotkb:YMR314W(locus name)|uniprotkb:YM9924.06(orf name)|uniprotkb:Proteasome component PRE5(gene name synonym)|uniprotkb:Macropain subunit PRE5(gene name synonym)|uniprotkb:Proteinase YSCE subunit PRE5(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit PRE5(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11530596|imex:IM-24995-865	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-748974(isoform-parent)|ensembl:ENST00000378752(transcript)|ensembl:ENST00000378764(transcript)|ensembl:ENSG00000123240(gene)|uniprotkb:Q96CV9-2(isoform-parent)|entrezgene/locuslink:10133(identity)	rcsb pdb:4Y8T|rcsb pdb:4Y8U|rcsb pdb:4Y9Y|rcsb pdb:4Y9Z|rcsb pdb:4YA0|rcsb pdb:4YA1|rcsb pdb:4YA2|rcsb pdb:4YA3|rcsb pdb:4YA4|rcsb pdb:4YA5|rcsb pdb:4Y7X|rcsb pdb:4Y7Y|rcsb pdb:4Y80|rcsb pdb:4Y81|rcsb pdb:4Y82|rcsb pdb:4Y84|rcsb pdb:4Y8G|rcsb pdb:4Y8H|rcsb pdb:4Y8I|rcsb pdb:4Y8J|rcsb pdb:4Y8K|rcsb pdb:4Y8L|rcsb pdb:4Y8M|rcsb pdb:4Y8N|rcsb pdb:4Y8O|rcsb pdb:4Y8P|rcsb pdb:4Y8Q|rcsb pdb:4Y8R|rcsb pdb:4Y8S|rcsb pdb:5FG7|rcsb pdb:5FG9|rcsb pdb:5FGA|rcsb pdb:4YA7|rcsb pdb:4YA9|rcsb pdb:4Z1L|rcsb pdb:5A5B|rcsb pdb:5AHJ|rcsb pdb:5BOU|rcsb pdb:5BXL|rcsb pdb:5BXN|rcsb pdb:5CGF|rcsb pdb:5CGG|rcsb pdb:5CGH|rcsb pdb:5CGI|rcsb pdb:5CZ4|rcsb pdb:5CZ5|rcsb pdb:5CZ6|rcsb pdb:5CZ7|rcsb pdb:5CZ8|rcsb pdb:5CZ9|rcsb pdb:5CZA|rcsb pdb:5D0S|rcsb pdb:5D0T|rcsb pdb:5D0V|rcsb pdb:5D0W|rcsb pdb:5D0X|rcsb pdb:5D0Z|rcsb pdb:5DKI|rcsb pdb:5DKJ|rcsb pdb:5FGD|rcsb pdb:3HYE|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:3MG0|rcsb pdb:3MG4|rcsb pdb:3MG6|rcsb pdb:3MG7|rcsb pdb:3MG8|rcsb pdb:3NZJ|rcsb pdb:3NZW|rcsb pdb:3NZX|rcsb pdb:3OEU|rcsb pdb:3OEV|rcsb pdb:3OKJ|rcsb pdb:3SDI|rcsb pdb:3SDK|rcsb pdb:3SHJ|rcsb pdb:3TDD|rcsb pdb:3UN4|rcsb pdb:3UN8|rcsb pdb:3WXR|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:4EU2|rcsb pdb:4FZC|rcsb pdb:4FZG|rcsb pdb:4G4S|rcsb pdb:4GK7|rcsb pdb:4HNP|rcsb pdb:4HRC|rcsb pdb:4HRD|rcsb pdb:4INR|rcsb pdb:4INT|rcsb pdb:4INU|rcsb pdb:4J70|rcsb pdb:4JSQ|rcsb pdb:4JSU|rcsb pdb:4JT0|rcsb pdb:4LQI|rcsb pdb:4LTC|rcsb pdb:4NNN|rcsb pdb:4NNW|rcsb pdb:4NO1|rcsb pdb:4NO6|rcsb pdb:4NO8|rcsb pdb:4NO9|rcsb pdb:5FGE|rcsb pdb:5FGF|rcsb pdb:5FGG|rcsb pdb:5FGH|rcsb pdb:5FGI|rcsb pdb:5FHS|rcsb pdb:5JHR|rcsb pdb:5JHS|rcsb pdb:5L52|rcsb pdb:5L54|rcsb pdb:5L55|rcsb pdb:5L5A|rcsb pdb:5L5B|rcsb pdb:5L5D|rcsb pdb:5L5E|rcsb pdb:5L5F|rcsb pdb:5L5H|rcsb pdb:5L5I|rcsb pdb:5L5J|rcsb pdb:5L5O|rcsb pdb:5L5P|rcsb pdb:5L5Q|rcsb pdb:5L5R|rcsb pdb:4Q1S|rcsb pdb:4QBY|rcsb pdb:4QLQ|rcsb pdb:4QLS|rcsb pdb:4QLT|rcsb pdb:4QLU|rcsb pdb:4QLV|rcsb pdb:4QUX|rcsb pdb:4QUY|rcsb pdb:4QV0|rcsb pdb:4QV1|rcsb pdb:4QV3|rcsb pdb:4QV4|rcsb pdb:4QV5|rcsb pdb:4QV6|rcsb pdb:4QV7|rcsb pdb:4QV8|rcsb pdb:4QV9|rcsb pdb:4QVL|ensemblfungi:YMR314W(gene)|ensemblfungi:YMR314W_mRNA(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0042175"(nuclear outer membrane-endoplasmic reticulum membrane network)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR035144|rcsb pdb:1FNT|rcsb pdb:1G0U|rcsb pdb:1G65|rcsb pdb:1JD2|rcsb pdb:1RYP|rcsb pdb:1Z7Q|rcsb pdb:2F16|rcsb pdb:2FAK|rcsb pdb:2GPL|rcsb pdb:2ZCY|rcsb pdb:3BDM|rcsb pdb:3D29|rcsb pdb:3DY3|rcsb pdb:3DY4|rcsb pdb:3E47|rcsb pdb:3GPJ|rcsb pdb:3GPT|rcsb pdb:3GPW|rcsb pdb:4QVM|rcsb pdb:4QVN|rcsb pdb:4QVP|rcsb pdb:4QVQ|rcsb pdb:4QVV|rcsb pdb:4QVW|rcsb pdb:4QVY|rcsb pdb:4QW0|rcsb pdb:4QW1|rcsb pdb:4QW3|rcsb pdb:4QW4|rcsb pdb:4QW5|rcsb pdb:4QW6|rcsb pdb:4QW7|rcsb pdb:4QWF|rcsb pdb:4QWG|rcsb pdb:4QWI|rcsb pdb:4QWJ|rcsb pdb:4QWK|rcsb pdb:4QWL|rcsb pdb:4QWR|rcsb pdb:4QWS|rcsb pdb:4QWU|rcsb pdb:4QWX|rcsb pdb:4QXJ|rcsb pdb:4QZ0|rcsb pdb:4QZ1|rcsb pdb:4QZ2|rcsb pdb:4QZ3|rcsb pdb:4QZ4|rcsb pdb:4QZ5|rcsb pdb:4QZ6|rcsb pdb:4QZ7|rcsb pdb:4QZW|rcsb pdb:4QZX|rcsb pdb:4QZZ|rcsb pdb:4R00|rcsb pdb:4R02|rcsb pdb:4R17|rcsb pdb:4R18|rcsb pdb:4RUR|rcsb pdb:4V7O|rcsb pdb:4X6Z|rcsb pdb:4Y69|rcsb pdb:4Y6A|rcsb pdb:4Y6V|rcsb pdb:4Y6Z|rcsb pdb:4Y70|rcsb pdb:4Y74|rcsb pdb:4Y75|rcsb pdb:4Y77|rcsb pdb:4Y78|rcsb pdb:4Y7W|rcsb pdb:5LTT|rcsb pdb:5M2B|rcsb pdb:5MP9|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5NIF|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6G7F|rcsb pdb:6G8M|rcsb pdb:6G8N|rcsb pdb:6GOP|rcsb pdb:6H39|rcsb pdb:6HTB|rcsb pdb:6HTC|rcsb pdb:6HTD|rcsb pdb:6HTP|rcsb pdb:6HTR|rcsb pdb:6HUB|rcsb pdb:6HUC|rcsb pdb:6HUQ|rcsb pdb:6HUU|rcsb pdb:6HUV|rcsb pdb:6HV3|rcsb pdb:6HV4|rcsb pdb:6HV5|rcsb pdb:6HV7|rcsb pdb:6HVA|rcsb pdb:6HVR|rcsb pdb:6HVS|rcsb pdb:6HVT|rcsb pdb:6HVU|rcsb pdb:6HVV|rcsb pdb:5L5S|rcsb pdb:5L5T|rcsb pdb:5L5U|rcsb pdb:5L5V|rcsb pdb:5L5W|rcsb pdb:5L5X|rcsb pdb:5L5Y|rcsb pdb:5L5Z|rcsb pdb:5L60|rcsb pdb:5L61|rcsb pdb:5L62|rcsb pdb:5L63|rcsb pdb:5L64|rcsb pdb:5L65|rcsb pdb:5L66|rcsb pdb:5L67|rcsb pdb:5L68|rcsb pdb:5L69|rcsb pdb:5L6A|rcsb pdb:5L6B|rcsb pdb:5L6C|rcsb pdb:5LAI|rcsb pdb:5LAJ|rcsb pdb:6HVW|rcsb pdb:6HVX|rcsb pdb:6HVY|rcsb pdb:6HW0|rcsb pdb:6HW3|rcsb pdb:6HW4|rcsb pdb:6HW5|rcsb pdb:6HW6|rcsb pdb:6HW7|rcsb pdb:6HW8|rcsb pdb:6HW9|rcsb pdb:6HWA|rcsb pdb:6HWB|rcsb pdb:6HWC|rcsb pdb:6HWD|rcsb pdb:6HWE|rcsb pdb:6HWF|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2X|rcsb pdb:6J30|rcsb pdb:6ZOU|rcsb pdb:6ZP6|rcsb pdb:6ZP8|rcsb pdb:7LS5|rcsb pdb:7LS6|rcsb pdb:7LSX|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|rcsb pdb:6J2Q|refseq:NP_014045.1|sgd:S000004931|mint:P40302|dip:DIP-1528N|sgd:YMR314W(identity)	-	isoform-comment:No experimental confirmation available.	crc64:C43CBCC1C6B9E39E	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2018/04/06	rogid:ygzEQkiDJwDAMUuFQuOWsSIqwAk9606	rogid:C9GPb0JAklkBz0t/YYqRMNEiQss559292	intact-crc:9AB649F194699DF0|rigid:oIuyRqKqPpz576ZXWukSRwQC/v4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96CV9	uniprotkb:P40302	intact:EBI-748974|uniprotkb:Q5T672|uniprotkb:Q5T673|uniprotkb:Q5T674|uniprotkb:Q5T675|uniprotkb:Q7LDL9|uniprotkb:Q8N562|uniprotkb:Q9UET9|uniprotkb:Q9UEV4|uniprotkb:Q9Y218|uniprotkb:B3KP00|uniprotkb:D3DRS4|uniprotkb:D3DRS8|ensembl:ENSP00000263036|ensembl:ENSP00000368021|ensembl:ENSP00000368022|ensembl:ENSP00000368032	intact:EBI-13955|ensemblfungi:YMR314W|uniprotkb:D6W0E1	psi-mi:optn_human(display_long)|uniprotkb:HYPL(gene name synonym)|uniprotkb:Optic neuropathy-inducing protein(gene name synonym)|uniprotkb:E3-14.7K-interacting protein(gene name synonym)|uniprotkb:FIP-2(gene name synonym)|uniprotkb:Huntingtin-interacting protein L(gene name synonym)|uniprotkb:Huntingtin yeast partner L(gene name synonym)|uniprotkb:NEMO-related protein(gene name synonym)|uniprotkb:Transcription factor IIIA-interacting protein(gene name synonym)|uniprotkb:OPTN(gene name)|psi-mi:OPTN(display_short)|uniprotkb:FIP2(gene name synonym)|uniprotkb:GLC1E(gene name synonym)|uniprotkb:NRP(gene name synonym)|uniprotkb:HIP7(gene name synonym)|uniprotkb:Huntingtin-interacting protein 7(gene name synonym)	psi-mi:psa6_yeast(display_long)|uniprotkb:PRE5(gene name)|psi-mi:PRE5(display_short)|uniprotkb:YMR314W(locus name)|uniprotkb:YM9924.06(orf name)|uniprotkb:Proteasome component PRE5(gene name synonym)|uniprotkb:Macropain subunit PRE5(gene name synonym)|uniprotkb:Proteinase YSCE subunit PRE5(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit PRE5(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11530587|imex:IM-24995-864	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001008212.1|refseq:NP_001008213.1|refseq:NP_001008214.1|refseq:NP_068815.2|ensembl:ENSG00000123240(gene)|ensembl:ENST00000263036(transcript)|ensembl:ENST00000378747(transcript)|ensembl:ENST00000378748(transcript)|ensembl:ENST00000378757(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001920"(negative regulation of receptor recycling)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0007030"(Golgi organization)|go:"GO:0007165"(signal transduction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008219"(cell death)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0061734"(parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:1904417"(positive regulation of xenophagy)|interpro:IPR021063|interpro:IPR032419|interpro:IPR032939|interpro:IPR034735|mint:Q96CV9|rcsb pdb:2LO4|rcsb pdb:2LUE|rcsb pdb:3VTV|rcsb pdb:3VTW|rcsb pdb:5AAZ|rcsb pdb:5B83|rcsb pdb:5EOA|rcsb pdb:5EOF|rcsb pdb:7CZM|reactome:R-HSA-2565942|reactome:R-HSA-8854214|dip:DIP-42001N|entrezgene/locuslink:10133(identity)	rcsb pdb:4Y8T|rcsb pdb:4Y8U|rcsb pdb:4Y9Y|rcsb pdb:4Y9Z|rcsb pdb:4YA0|rcsb pdb:4YA1|rcsb pdb:4YA2|rcsb pdb:4YA3|rcsb pdb:4YA4|rcsb pdb:4YA5|rcsb pdb:4Y7X|rcsb pdb:4Y7Y|rcsb pdb:4Y80|rcsb pdb:4Y81|rcsb pdb:4Y82|rcsb pdb:4Y84|rcsb pdb:4Y8G|rcsb pdb:4Y8H|rcsb pdb:4Y8I|rcsb pdb:4Y8J|rcsb pdb:4Y8K|rcsb pdb:4Y8L|rcsb pdb:4Y8M|rcsb pdb:4Y8N|rcsb pdb:4Y8O|rcsb pdb:4Y8P|rcsb pdb:4Y8Q|rcsb pdb:4Y8R|rcsb pdb:4Y8S|rcsb pdb:5FG7|rcsb pdb:5FG9|rcsb pdb:5FGA|rcsb pdb:4YA7|rcsb pdb:4YA9|rcsb pdb:4Z1L|rcsb pdb:5A5B|rcsb pdb:5AHJ|rcsb pdb:5BOU|rcsb pdb:5BXL|rcsb pdb:5BXN|rcsb pdb:5CGF|rcsb pdb:5CGG|rcsb pdb:5CGH|rcsb pdb:5CGI|rcsb pdb:5CZ4|rcsb pdb:5CZ5|rcsb pdb:5CZ6|rcsb pdb:5CZ7|rcsb pdb:5CZ8|rcsb pdb:5CZ9|rcsb pdb:5CZA|rcsb pdb:5D0S|rcsb pdb:5D0T|rcsb pdb:5D0V|rcsb pdb:5D0W|rcsb pdb:5D0X|rcsb pdb:5D0Z|rcsb pdb:5DKI|rcsb pdb:5DKJ|rcsb pdb:5FGD|rcsb pdb:3HYE|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:3MG0|rcsb pdb:3MG4|rcsb pdb:3MG6|rcsb pdb:3MG7|rcsb pdb:3MG8|rcsb pdb:3NZJ|rcsb pdb:3NZW|rcsb pdb:3NZX|rcsb pdb:3OEU|rcsb pdb:3OEV|rcsb pdb:3OKJ|rcsb pdb:3SDI|rcsb pdb:3SDK|rcsb pdb:3SHJ|rcsb pdb:3TDD|rcsb pdb:3UN4|rcsb pdb:3UN8|rcsb pdb:3WXR|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:4EU2|rcsb pdb:4FZC|rcsb pdb:4FZG|rcsb pdb:4G4S|rcsb pdb:4GK7|rcsb pdb:4HNP|rcsb pdb:4HRC|rcsb pdb:4HRD|rcsb pdb:4INR|rcsb pdb:4INT|rcsb pdb:4INU|rcsb pdb:4J70|rcsb pdb:4JSQ|rcsb pdb:4JSU|rcsb pdb:4JT0|rcsb pdb:4LQI|rcsb pdb:4LTC|rcsb pdb:4NNN|rcsb pdb:4NNW|rcsb pdb:4NO1|rcsb pdb:4NO6|rcsb pdb:4NO8|rcsb pdb:4NO9|rcsb pdb:5FGE|rcsb pdb:5FGF|rcsb pdb:5FGG|rcsb pdb:5FGH|rcsb pdb:5FGI|rcsb pdb:5FHS|rcsb pdb:5JHR|rcsb pdb:5JHS|rcsb pdb:5L52|rcsb pdb:5L54|rcsb pdb:5L55|rcsb pdb:5L5A|rcsb pdb:5L5B|rcsb pdb:5L5D|rcsb pdb:5L5E|rcsb pdb:5L5F|rcsb pdb:5L5H|rcsb pdb:5L5I|rcsb pdb:5L5J|rcsb pdb:5L5O|rcsb pdb:5L5P|rcsb pdb:5L5Q|rcsb pdb:5L5R|rcsb pdb:4Q1S|rcsb pdb:4QBY|rcsb pdb:4QLQ|rcsb pdb:4QLS|rcsb pdb:4QLT|rcsb pdb:4QLU|rcsb pdb:4QLV|rcsb pdb:4QUX|rcsb pdb:4QUY|rcsb pdb:4QV0|rcsb pdb:4QV1|rcsb pdb:4QV3|rcsb pdb:4QV4|rcsb pdb:4QV5|rcsb pdb:4QV6|rcsb pdb:4QV7|rcsb pdb:4QV8|rcsb pdb:4QV9|rcsb pdb:4QVL|ensemblfungi:YMR314W(gene)|ensemblfungi:YMR314W_mRNA(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0042175"(nuclear outer membrane-endoplasmic reticulum membrane network)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR035144|rcsb pdb:1FNT|rcsb pdb:1G0U|rcsb pdb:1G65|rcsb pdb:1JD2|rcsb pdb:1RYP|rcsb pdb:1Z7Q|rcsb pdb:2F16|rcsb pdb:2FAK|rcsb pdb:2GPL|rcsb pdb:2ZCY|rcsb pdb:3BDM|rcsb pdb:3D29|rcsb pdb:3DY3|rcsb pdb:3DY4|rcsb pdb:3E47|rcsb pdb:3GPJ|rcsb pdb:3GPT|rcsb pdb:3GPW|rcsb pdb:4QVM|rcsb pdb:4QVN|rcsb pdb:4QVP|rcsb pdb:4QVQ|rcsb pdb:4QVV|rcsb pdb:4QVW|rcsb pdb:4QVY|rcsb pdb:4QW0|rcsb pdb:4QW1|rcsb pdb:4QW3|rcsb pdb:4QW4|rcsb pdb:4QW5|rcsb pdb:4QW6|rcsb pdb:4QW7|rcsb pdb:4QWF|rcsb pdb:4QWG|rcsb pdb:4QWI|rcsb pdb:4QWJ|rcsb pdb:4QWK|rcsb pdb:4QWL|rcsb pdb:4QWR|rcsb pdb:4QWS|rcsb pdb:4QWU|rcsb pdb:4QWX|rcsb pdb:4QXJ|rcsb pdb:4QZ0|rcsb pdb:4QZ1|rcsb pdb:4QZ2|rcsb pdb:4QZ3|rcsb pdb:4QZ4|rcsb pdb:4QZ5|rcsb pdb:4QZ6|rcsb pdb:4QZ7|rcsb pdb:4QZW|rcsb pdb:4QZX|rcsb pdb:4QZZ|rcsb pdb:4R00|rcsb pdb:4R02|rcsb pdb:4R17|rcsb pdb:4R18|rcsb pdb:4RUR|rcsb pdb:4V7O|rcsb pdb:4X6Z|rcsb pdb:4Y69|rcsb pdb:4Y6A|rcsb pdb:4Y6V|rcsb pdb:4Y6Z|rcsb pdb:4Y70|rcsb pdb:4Y74|rcsb pdb:4Y75|rcsb pdb:4Y77|rcsb pdb:4Y78|rcsb pdb:4Y7W|rcsb pdb:5LTT|rcsb pdb:5M2B|rcsb pdb:5MP9|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5NIF|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6G7F|rcsb pdb:6G8M|rcsb pdb:6G8N|rcsb pdb:6GOP|rcsb pdb:6H39|rcsb pdb:6HTB|rcsb pdb:6HTC|rcsb pdb:6HTD|rcsb pdb:6HTP|rcsb pdb:6HTR|rcsb pdb:6HUB|rcsb pdb:6HUC|rcsb pdb:6HUQ|rcsb pdb:6HUU|rcsb pdb:6HUV|rcsb pdb:6HV3|rcsb pdb:6HV4|rcsb pdb:6HV5|rcsb pdb:6HV7|rcsb pdb:6HVA|rcsb pdb:6HVR|rcsb pdb:6HVS|rcsb pdb:6HVT|rcsb pdb:6HVU|rcsb pdb:6HVV|rcsb pdb:5L5S|rcsb pdb:5L5T|rcsb pdb:5L5U|rcsb pdb:5L5V|rcsb pdb:5L5W|rcsb pdb:5L5X|rcsb pdb:5L5Y|rcsb pdb:5L5Z|rcsb pdb:5L60|rcsb pdb:5L61|rcsb pdb:5L62|rcsb pdb:5L63|rcsb pdb:5L64|rcsb pdb:5L65|rcsb pdb:5L66|rcsb pdb:5L67|rcsb pdb:5L68|rcsb pdb:5L69|rcsb pdb:5L6A|rcsb pdb:5L6B|rcsb pdb:5L6C|rcsb pdb:5LAI|rcsb pdb:5LAJ|rcsb pdb:6HVW|rcsb pdb:6HVX|rcsb pdb:6HVY|rcsb pdb:6HW0|rcsb pdb:6HW3|rcsb pdb:6HW4|rcsb pdb:6HW5|rcsb pdb:6HW6|rcsb pdb:6HW7|rcsb pdb:6HW8|rcsb pdb:6HW9|rcsb pdb:6HWA|rcsb pdb:6HWB|rcsb pdb:6HWC|rcsb pdb:6HWD|rcsb pdb:6HWE|rcsb pdb:6HWF|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2X|rcsb pdb:6J30|rcsb pdb:6ZOU|rcsb pdb:6ZP6|rcsb pdb:6ZP8|rcsb pdb:7LS5|rcsb pdb:7LS6|rcsb pdb:7LSX|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|rcsb pdb:6J2Q|refseq:NP_014045.1|sgd:S000004931|mint:P40302|dip:DIP-1528N|sgd:YMR314W(identity)	-	-	crc64:C43CBCC1C6B9E39E	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2018/04/06	rogid:jcCTXDx1bJq3K5mgNUD73jeWeBU9606	rogid:C9GPb0JAklkBz0t/YYqRMNEiQss559292	intact-crc:7A7976096ED087BC|rigid:cavY4vnk2ijUHCXNWZ63l8OL7sk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8TAP6	uniprotkb:P40302	intact:EBI-742887|ensembl:ENSP00000262127|uniprotkb:Q658N5|uniprotkb:Q9H9U7|uniprotkb:B0YJB2|uniprotkb:B4DXG5|uniprotkb:B4DZW1	intact:EBI-13955|ensemblfungi:YMR314W|uniprotkb:D6W0E1	psi-mi:cep76_human(display_long)|uniprotkb:CEP76(gene name)|psi-mi:CEP76(display_short)|uniprotkb:C18orf9(gene name synonym)	psi-mi:psa6_yeast(display_long)|uniprotkb:PRE5(gene name)|psi-mi:PRE5(display_short)|uniprotkb:YMR314W(locus name)|uniprotkb:YM9924.06(orf name)|uniprotkb:Proteasome component PRE5(gene name synonym)|uniprotkb:Macropain subunit PRE5(gene name synonym)|uniprotkb:Proteinase YSCE subunit PRE5(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit PRE5(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11530578|imex:IM-24995-863	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_079175.2|ensembl:ENSG00000101624(gene)|ensembl:ENST00000262127(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0046599"(regulation of centriole replication)|interpro:IPR028926|interpro:IPR038765|mint:Q8TAP6|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_001258918.1|entrezgene/locuslink:79959(identity)	rcsb pdb:4Y8T|rcsb pdb:4Y8U|rcsb pdb:4Y9Y|rcsb pdb:4Y9Z|rcsb pdb:4YA0|rcsb pdb:4YA1|rcsb pdb:4YA2|rcsb pdb:4YA3|rcsb pdb:4YA4|rcsb pdb:4YA5|rcsb pdb:4Y7X|rcsb pdb:4Y7Y|rcsb pdb:4Y80|rcsb pdb:4Y81|rcsb pdb:4Y82|rcsb pdb:4Y84|rcsb pdb:4Y8G|rcsb pdb:4Y8H|rcsb pdb:4Y8I|rcsb pdb:4Y8J|rcsb pdb:4Y8K|rcsb pdb:4Y8L|rcsb pdb:4Y8M|rcsb pdb:4Y8N|rcsb pdb:4Y8O|rcsb pdb:4Y8P|rcsb pdb:4Y8Q|rcsb pdb:4Y8R|rcsb pdb:4Y8S|rcsb pdb:5FG7|rcsb pdb:5FG9|rcsb pdb:5FGA|rcsb pdb:4YA7|rcsb pdb:4YA9|rcsb pdb:4Z1L|rcsb pdb:5A5B|rcsb pdb:5AHJ|rcsb pdb:5BOU|rcsb pdb:5BXL|rcsb pdb:5BXN|rcsb pdb:5CGF|rcsb pdb:5CGG|rcsb pdb:5CGH|rcsb pdb:5CGI|rcsb pdb:5CZ4|rcsb pdb:5CZ5|rcsb pdb:5CZ6|rcsb pdb:5CZ7|rcsb pdb:5CZ8|rcsb pdb:5CZ9|rcsb pdb:5CZA|rcsb pdb:5D0S|rcsb pdb:5D0T|rcsb pdb:5D0V|rcsb pdb:5D0W|rcsb pdb:5D0X|rcsb pdb:5D0Z|rcsb pdb:5DKI|rcsb pdb:5DKJ|rcsb pdb:5FGD|rcsb pdb:3HYE|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:3MG0|rcsb pdb:3MG4|rcsb pdb:3MG6|rcsb pdb:3MG7|rcsb pdb:3MG8|rcsb pdb:3NZJ|rcsb pdb:3NZW|rcsb pdb:3NZX|rcsb pdb:3OEU|rcsb pdb:3OEV|rcsb pdb:3OKJ|rcsb pdb:3SDI|rcsb pdb:3SDK|rcsb pdb:3SHJ|rcsb pdb:3TDD|rcsb pdb:3UN4|rcsb pdb:3UN8|rcsb pdb:3WXR|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:4EU2|rcsb pdb:4FZC|rcsb pdb:4FZG|rcsb pdb:4G4S|rcsb pdb:4GK7|rcsb pdb:4HNP|rcsb pdb:4HRC|rcsb pdb:4HRD|rcsb pdb:4INR|rcsb pdb:4INT|rcsb pdb:4INU|rcsb pdb:4J70|rcsb pdb:4JSQ|rcsb pdb:4JSU|rcsb pdb:4JT0|rcsb pdb:4LQI|rcsb pdb:4LTC|rcsb pdb:4NNN|rcsb pdb:4NNW|rcsb pdb:4NO1|rcsb pdb:4NO6|rcsb pdb:4NO8|rcsb pdb:4NO9|rcsb pdb:5FGE|rcsb pdb:5FGF|rcsb pdb:5FGG|rcsb pdb:5FGH|rcsb pdb:5FGI|rcsb pdb:5FHS|rcsb pdb:5JHR|rcsb pdb:5JHS|rcsb pdb:5L52|rcsb pdb:5L54|rcsb pdb:5L55|rcsb pdb:5L5A|rcsb pdb:5L5B|rcsb pdb:5L5D|rcsb pdb:5L5E|rcsb pdb:5L5F|rcsb pdb:5L5H|rcsb pdb:5L5I|rcsb pdb:5L5J|rcsb pdb:5L5O|rcsb pdb:5L5P|rcsb pdb:5L5Q|rcsb pdb:5L5R|rcsb pdb:4Q1S|rcsb pdb:4QBY|rcsb pdb:4QLQ|rcsb pdb:4QLS|rcsb pdb:4QLT|rcsb pdb:4QLU|rcsb pdb:4QLV|rcsb pdb:4QUX|rcsb pdb:4QUY|rcsb pdb:4QV0|rcsb pdb:4QV1|rcsb pdb:4QV3|rcsb pdb:4QV4|rcsb pdb:4QV5|rcsb pdb:4QV6|rcsb pdb:4QV7|rcsb pdb:4QV8|rcsb pdb:4QV9|rcsb pdb:4QVL|ensemblfungi:YMR314W(gene)|ensemblfungi:YMR314W_mRNA(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0042175"(nuclear outer membrane-endoplasmic reticulum membrane network)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR035144|rcsb pdb:1FNT|rcsb pdb:1G0U|rcsb pdb:1G65|rcsb pdb:1JD2|rcsb pdb:1RYP|rcsb pdb:1Z7Q|rcsb pdb:2F16|rcsb pdb:2FAK|rcsb pdb:2GPL|rcsb pdb:2ZCY|rcsb pdb:3BDM|rcsb pdb:3D29|rcsb pdb:3DY3|rcsb pdb:3DY4|rcsb pdb:3E47|rcsb pdb:3GPJ|rcsb pdb:3GPT|rcsb pdb:3GPW|rcsb pdb:4QVM|rcsb pdb:4QVN|rcsb pdb:4QVP|rcsb pdb:4QVQ|rcsb pdb:4QVV|rcsb pdb:4QVW|rcsb pdb:4QVY|rcsb pdb:4QW0|rcsb pdb:4QW1|rcsb pdb:4QW3|rcsb pdb:4QW4|rcsb pdb:4QW5|rcsb pdb:4QW6|rcsb pdb:4QW7|rcsb pdb:4QWF|rcsb pdb:4QWG|rcsb pdb:4QWI|rcsb pdb:4QWJ|rcsb pdb:4QWK|rcsb pdb:4QWL|rcsb pdb:4QWR|rcsb pdb:4QWS|rcsb pdb:4QWU|rcsb pdb:4QWX|rcsb pdb:4QXJ|rcsb pdb:4QZ0|rcsb pdb:4QZ1|rcsb pdb:4QZ2|rcsb pdb:4QZ3|rcsb pdb:4QZ4|rcsb pdb:4QZ5|rcsb pdb:4QZ6|rcsb pdb:4QZ7|rcsb pdb:4QZW|rcsb pdb:4QZX|rcsb pdb:4QZZ|rcsb pdb:4R00|rcsb pdb:4R02|rcsb pdb:4R17|rcsb pdb:4R18|rcsb pdb:4RUR|rcsb pdb:4V7O|rcsb pdb:4X6Z|rcsb pdb:4Y69|rcsb pdb:4Y6A|rcsb pdb:4Y6V|rcsb pdb:4Y6Z|rcsb pdb:4Y70|rcsb pdb:4Y74|rcsb pdb:4Y75|rcsb pdb:4Y77|rcsb pdb:4Y78|rcsb pdb:4Y7W|rcsb pdb:5LTT|rcsb pdb:5M2B|rcsb pdb:5MP9|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5NIF|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6G7F|rcsb pdb:6G8M|rcsb pdb:6G8N|rcsb pdb:6GOP|rcsb pdb:6H39|rcsb pdb:6HTB|rcsb pdb:6HTC|rcsb pdb:6HTD|rcsb pdb:6HTP|rcsb pdb:6HTR|rcsb pdb:6HUB|rcsb pdb:6HUC|rcsb pdb:6HUQ|rcsb pdb:6HUU|rcsb pdb:6HUV|rcsb pdb:6HV3|rcsb pdb:6HV4|rcsb pdb:6HV5|rcsb pdb:6HV7|rcsb pdb:6HVA|rcsb pdb:6HVR|rcsb pdb:6HVS|rcsb pdb:6HVT|rcsb pdb:6HVU|rcsb pdb:6HVV|rcsb pdb:5L5S|rcsb pdb:5L5T|rcsb pdb:5L5U|rcsb pdb:5L5V|rcsb pdb:5L5W|rcsb pdb:5L5X|rcsb pdb:5L5Y|rcsb pdb:5L5Z|rcsb pdb:5L60|rcsb pdb:5L61|rcsb pdb:5L62|rcsb pdb:5L63|rcsb pdb:5L64|rcsb pdb:5L65|rcsb pdb:5L66|rcsb pdb:5L67|rcsb pdb:5L68|rcsb pdb:5L69|rcsb pdb:5L6A|rcsb pdb:5L6B|rcsb pdb:5L6C|rcsb pdb:5LAI|rcsb pdb:5LAJ|rcsb pdb:6HVW|rcsb pdb:6HVX|rcsb pdb:6HVY|rcsb pdb:6HW0|rcsb pdb:6HW3|rcsb pdb:6HW4|rcsb pdb:6HW5|rcsb pdb:6HW6|rcsb pdb:6HW7|rcsb pdb:6HW8|rcsb pdb:6HW9|rcsb pdb:6HWA|rcsb pdb:6HWB|rcsb pdb:6HWC|rcsb pdb:6HWD|rcsb pdb:6HWE|rcsb pdb:6HWF|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2X|rcsb pdb:6J30|rcsb pdb:6ZOU|rcsb pdb:6ZP6|rcsb pdb:6ZP8|rcsb pdb:7LS5|rcsb pdb:7LS6|rcsb pdb:7LSX|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|rcsb pdb:6J2Q|refseq:NP_014045.1|sgd:S000004931|mint:P40302|dip:DIP-1528N|sgd:YMR314W(identity)	-	-	crc64:C43CBCC1C6B9E39E	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:fWzb8oIU35oVWomyDrf8u5sbxUk9606	rogid:C9GPb0JAklkBz0t/YYqRMNEiQss559292	intact-crc:49B29F24902A8B8F|rigid:DHzAsX9ZS6IcNW2eAj2hsBeJhXE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40302	uniprotkb:Q5JR59-3	intact:EBI-13955|ensemblfungi:YMR314W|uniprotkb:D6W0E1	intact:EBI-11522433|ensembl:ENSP00000370186	psi-mi:psa6_yeast(display_long)|uniprotkb:PRE5(gene name)|psi-mi:PRE5(display_short)|uniprotkb:YMR314W(locus name)|uniprotkb:YM9924.06(orf name)|uniprotkb:Proteasome component PRE5(gene name synonym)|uniprotkb:Macropain subunit PRE5(gene name synonym)|uniprotkb:Proteinase YSCE subunit PRE5(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit PRE5(gene name synonym)	psi-mi:q5jr59-3(display_long)|uniprotkb:MTUS2(gene name)|psi-mi:MTUS2(display_short)|uniprotkb:CAZIP(gene name synonym)|uniprotkb:Cardiac zipper protein(gene name synonym)|uniprotkb:KIAA0774(gene name synonym)|uniprotkb:Microtubule plus-end tracking protein TIP150(gene name synonym)|uniprotkb:TIP150(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11530569|imex:IM-24995-862	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:4Y8T|rcsb pdb:4Y8U|rcsb pdb:4Y9Y|rcsb pdb:4Y9Z|rcsb pdb:4YA0|rcsb pdb:4YA1|rcsb pdb:4YA2|rcsb pdb:4YA3|rcsb pdb:4YA4|rcsb pdb:4YA5|rcsb pdb:4Y7X|rcsb pdb:4Y7Y|rcsb pdb:4Y80|rcsb pdb:4Y81|rcsb pdb:4Y82|rcsb pdb:4Y84|rcsb pdb:4Y8G|rcsb pdb:4Y8H|rcsb pdb:4Y8I|rcsb pdb:4Y8J|rcsb pdb:4Y8K|rcsb pdb:4Y8L|rcsb pdb:4Y8M|rcsb pdb:4Y8N|rcsb pdb:4Y8O|rcsb pdb:4Y8P|rcsb pdb:4Y8Q|rcsb pdb:4Y8R|rcsb pdb:4Y8S|rcsb pdb:5FG7|rcsb pdb:5FG9|rcsb pdb:5FGA|rcsb pdb:4YA7|rcsb pdb:4YA9|rcsb pdb:4Z1L|rcsb pdb:5A5B|rcsb pdb:5AHJ|rcsb pdb:5BOU|rcsb pdb:5BXL|rcsb pdb:5BXN|rcsb pdb:5CGF|rcsb pdb:5CGG|rcsb pdb:5CGH|rcsb pdb:5CGI|rcsb pdb:5CZ4|rcsb pdb:5CZ5|rcsb pdb:5CZ6|rcsb pdb:5CZ7|rcsb pdb:5CZ8|rcsb pdb:5CZ9|rcsb pdb:5CZA|rcsb pdb:5D0S|rcsb pdb:5D0T|rcsb pdb:5D0V|rcsb pdb:5D0W|rcsb pdb:5D0X|rcsb pdb:5D0Z|rcsb pdb:5DKI|rcsb pdb:5DKJ|rcsb pdb:5FGD|rcsb pdb:3HYE|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:3MG0|rcsb pdb:3MG4|rcsb pdb:3MG6|rcsb pdb:3MG7|rcsb pdb:3MG8|rcsb pdb:3NZJ|rcsb pdb:3NZW|rcsb pdb:3NZX|rcsb pdb:3OEU|rcsb pdb:3OEV|rcsb pdb:3OKJ|rcsb pdb:3SDI|rcsb pdb:3SDK|rcsb pdb:3SHJ|rcsb pdb:3TDD|rcsb pdb:3UN4|rcsb pdb:3UN8|rcsb pdb:3WXR|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:4EU2|rcsb pdb:4FZC|rcsb pdb:4FZG|rcsb pdb:4G4S|rcsb pdb:4GK7|rcsb pdb:4HNP|rcsb pdb:4HRC|rcsb pdb:4HRD|rcsb pdb:4INR|rcsb pdb:4INT|rcsb pdb:4INU|rcsb pdb:4J70|rcsb pdb:4JSQ|rcsb pdb:4JSU|rcsb pdb:4JT0|rcsb pdb:4LQI|rcsb pdb:4LTC|rcsb pdb:4NNN|rcsb pdb:4NNW|rcsb pdb:4NO1|rcsb pdb:4NO6|rcsb pdb:4NO8|rcsb pdb:4NO9|rcsb pdb:5FGE|rcsb pdb:5FGF|rcsb pdb:5FGG|rcsb pdb:5FGH|rcsb pdb:5FGI|rcsb pdb:5FHS|rcsb pdb:5JHR|rcsb pdb:5JHS|rcsb pdb:5L52|rcsb pdb:5L54|rcsb pdb:5L55|rcsb pdb:5L5A|rcsb pdb:5L5B|rcsb pdb:5L5D|rcsb pdb:5L5E|rcsb pdb:5L5F|rcsb pdb:5L5H|rcsb pdb:5L5I|rcsb pdb:5L5J|rcsb pdb:5L5O|rcsb pdb:5L5P|rcsb pdb:5L5Q|rcsb pdb:5L5R|rcsb pdb:4Q1S|rcsb pdb:4QBY|rcsb pdb:4QLQ|rcsb pdb:4QLS|rcsb pdb:4QLT|rcsb pdb:4QLU|rcsb pdb:4QLV|rcsb pdb:4QUX|rcsb pdb:4QUY|rcsb pdb:4QV0|rcsb pdb:4QV1|rcsb pdb:4QV3|rcsb pdb:4QV4|rcsb pdb:4QV5|rcsb pdb:4QV6|rcsb pdb:4QV7|rcsb pdb:4QV8|rcsb pdb:4QV9|rcsb pdb:4QVL|ensemblfungi:YMR314W(gene)|ensemblfungi:YMR314W_mRNA(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0042175"(nuclear outer membrane-endoplasmic reticulum membrane network)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR035144|rcsb pdb:1FNT|rcsb pdb:1G0U|rcsb pdb:1G65|rcsb pdb:1JD2|rcsb pdb:1RYP|rcsb pdb:1Z7Q|rcsb pdb:2F16|rcsb pdb:2FAK|rcsb pdb:2GPL|rcsb pdb:2ZCY|rcsb pdb:3BDM|rcsb pdb:3D29|rcsb pdb:3DY3|rcsb pdb:3DY4|rcsb pdb:3E47|rcsb pdb:3GPJ|rcsb pdb:3GPT|rcsb pdb:3GPW|rcsb pdb:4QVM|rcsb pdb:4QVN|rcsb pdb:4QVP|rcsb pdb:4QVQ|rcsb pdb:4QVV|rcsb pdb:4QVW|rcsb pdb:4QVY|rcsb pdb:4QW0|rcsb pdb:4QW1|rcsb pdb:4QW3|rcsb pdb:4QW4|rcsb pdb:4QW5|rcsb pdb:4QW6|rcsb pdb:4QW7|rcsb pdb:4QWF|rcsb pdb:4QWG|rcsb pdb:4QWI|rcsb pdb:4QWJ|rcsb pdb:4QWK|rcsb pdb:4QWL|rcsb pdb:4QWR|rcsb pdb:4QWS|rcsb pdb:4QWU|rcsb pdb:4QWX|rcsb pdb:4QXJ|rcsb pdb:4QZ0|rcsb pdb:4QZ1|rcsb pdb:4QZ2|rcsb pdb:4QZ3|rcsb pdb:4QZ4|rcsb pdb:4QZ5|rcsb pdb:4QZ6|rcsb pdb:4QZ7|rcsb pdb:4QZW|rcsb pdb:4QZX|rcsb pdb:4QZZ|rcsb pdb:4R00|rcsb pdb:4R02|rcsb pdb:4R17|rcsb pdb:4R18|rcsb pdb:4RUR|rcsb pdb:4V7O|rcsb pdb:4X6Z|rcsb pdb:4Y69|rcsb pdb:4Y6A|rcsb pdb:4Y6V|rcsb pdb:4Y6Z|rcsb pdb:4Y70|rcsb pdb:4Y74|rcsb pdb:4Y75|rcsb pdb:4Y77|rcsb pdb:4Y78|rcsb pdb:4Y7W|rcsb pdb:5LTT|rcsb pdb:5M2B|rcsb pdb:5MP9|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5NIF|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6G7F|rcsb pdb:6G8M|rcsb pdb:6G8N|rcsb pdb:6GOP|rcsb pdb:6H39|rcsb pdb:6HTB|rcsb pdb:6HTC|rcsb pdb:6HTD|rcsb pdb:6HTP|rcsb pdb:6HTR|rcsb pdb:6HUB|rcsb pdb:6HUC|rcsb pdb:6HUQ|rcsb pdb:6HUU|rcsb pdb:6HUV|rcsb pdb:6HV3|rcsb pdb:6HV4|rcsb pdb:6HV5|rcsb pdb:6HV7|rcsb pdb:6HVA|rcsb pdb:6HVR|rcsb pdb:6HVS|rcsb pdb:6HVT|rcsb pdb:6HVU|rcsb pdb:6HVV|rcsb pdb:5L5S|rcsb pdb:5L5T|rcsb pdb:5L5U|rcsb pdb:5L5V|rcsb pdb:5L5W|rcsb pdb:5L5X|rcsb pdb:5L5Y|rcsb pdb:5L5Z|rcsb pdb:5L60|rcsb pdb:5L61|rcsb pdb:5L62|rcsb pdb:5L63|rcsb pdb:5L64|rcsb pdb:5L65|rcsb pdb:5L66|rcsb pdb:5L67|rcsb pdb:5L68|rcsb pdb:5L69|rcsb pdb:5L6A|rcsb pdb:5L6B|rcsb pdb:5L6C|rcsb pdb:5LAI|rcsb pdb:5LAJ|rcsb pdb:6HVW|rcsb pdb:6HVX|rcsb pdb:6HVY|rcsb pdb:6HW0|rcsb pdb:6HW3|rcsb pdb:6HW4|rcsb pdb:6HW5|rcsb pdb:6HW6|rcsb pdb:6HW7|rcsb pdb:6HW8|rcsb pdb:6HW9|rcsb pdb:6HWA|rcsb pdb:6HWB|rcsb pdb:6HWC|rcsb pdb:6HWD|rcsb pdb:6HWE|rcsb pdb:6HWF|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2X|rcsb pdb:6J30|rcsb pdb:6ZOU|rcsb pdb:6ZP6|rcsb pdb:6ZP8|rcsb pdb:7LS5|rcsb pdb:7LS6|rcsb pdb:7LSX|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|rcsb pdb:6J2Q|refseq:NP_014045.1|sgd:S000004931|mint:P40302|dip:DIP-1528N|sgd:YMR314W(identity)	ensembl:ENSG00000132938(gene)|ensembl:ENST00000380808(transcript)|intact:EBI-742948(isoform-parent)|uniprotkb:Q5JR59-3(isoform-parent)|entrezgene/locuslink:23281(identity)	-	crc64:C43CBCC1C6B9E39E	isoform-comment:No experimental confirmation available.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:C9GPb0JAklkBz0t/YYqRMNEiQss559292	rogid:npId9tC7VoLN/jteoBiRbSYChPs9606	intact-crc:EF4B7E0EFC18AA47|rigid:VE5JD2ppecB/NGSKdKwKlvM1j3o	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9NSC5	uniprotkb:P40302	intact:EBI-748420|uniprotkb:O14580|uniprotkb:O95350|uniprotkb:Q9NSB9|uniprotkb:Q9NSC0|intact:EBI-2557809|uniprotkb:E9PCW9|uniprotkb:Q9NSC1|intact:EBI-28972925|ensembl:ENSP00000376162|ensembl:ENSP00000439937|ensembl:ENSP00000446026|intact:EBI-10175777|uniprotkb:B2RA10	intact:EBI-13955|ensemblfungi:YMR314W|uniprotkb:D6W0E1	psi-mi:home3_human(display_long)|uniprotkb:HOMER3(gene name)|psi-mi:HOMER3(display_short)	psi-mi:psa6_yeast(display_long)|uniprotkb:PRE5(gene name)|psi-mi:PRE5(display_short)|uniprotkb:YMR314W(locus name)|uniprotkb:YM9924.06(orf name)|uniprotkb:Proteasome component PRE5(gene name synonym)|uniprotkb:Macropain subunit PRE5(gene name synonym)|uniprotkb:Proteinase YSCE subunit PRE5(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit PRE5(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11530627|imex:IM-24995-868	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000221222|ensembl:ENSP00000221222|ensembl:ENSP00000376162|ensembl:ENST00000433218|ensembl:ENSP00000396154|ensembl:ENSP00000439937|ensembl:ENSP00000446026|ensembl:ENST00000594439|ensembl:ENSP00000471835|refseq:XP_006723006.1|refseq:XP_006723007.1|refseq:NP_001139193.1|refseq:NP_001139194.1|refseq:NP_004829.3|refseq:NP_001139196.1|ensembl:ENSG00000051128(gene)|ensembl:ENST00000392351(transcript)|ensembl:ENST00000539827(transcript)|ensembl:ENST00000542541(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006605"(protein targeting)|go:"GO:0007216"(G protein-coupled glutamate receptor signaling pathway)|go:"GO:0014069"(postsynaptic density)|go:"GO:0030425"(dendrite)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0035256"(G protein-coupled glutamate receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|go:"GO:2001256"(regulation of store-operated calcium entry)|interpro:IPR000697(EVH1)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR044100|mint:Q9NSC5|rcsb pdb:2P8V|rcsb pdb:3CVF|reactome:R-HSA-6794361|entrezgene/locuslink:9454(identity)	rcsb pdb:4Y8T|rcsb pdb:4Y8U|rcsb pdb:4Y9Y|rcsb pdb:4Y9Z|rcsb pdb:4YA0|rcsb pdb:4YA1|rcsb pdb:4YA2|rcsb pdb:4YA3|rcsb pdb:4YA4|rcsb pdb:4YA5|rcsb pdb:4Y7X|rcsb pdb:4Y7Y|rcsb pdb:4Y80|rcsb pdb:4Y81|rcsb pdb:4Y82|rcsb pdb:4Y84|rcsb pdb:4Y8G|rcsb pdb:4Y8H|rcsb pdb:4Y8I|rcsb pdb:4Y8J|rcsb pdb:4Y8K|rcsb pdb:4Y8L|rcsb pdb:4Y8M|rcsb pdb:4Y8N|rcsb pdb:4Y8O|rcsb pdb:4Y8P|rcsb pdb:4Y8Q|rcsb pdb:4Y8R|rcsb pdb:4Y8S|rcsb pdb:5FG7|rcsb pdb:5FG9|rcsb pdb:5FGA|rcsb pdb:4YA7|rcsb pdb:4YA9|rcsb pdb:4Z1L|rcsb pdb:5A5B|rcsb pdb:5AHJ|rcsb pdb:5BOU|rcsb pdb:5BXL|rcsb pdb:5BXN|rcsb pdb:5CGF|rcsb pdb:5CGG|rcsb pdb:5CGH|rcsb pdb:5CGI|rcsb pdb:5CZ4|rcsb pdb:5CZ5|rcsb pdb:5CZ6|rcsb pdb:5CZ7|rcsb pdb:5CZ8|rcsb pdb:5CZ9|rcsb pdb:5CZA|rcsb pdb:5D0S|rcsb pdb:5D0T|rcsb pdb:5D0V|rcsb pdb:5D0W|rcsb pdb:5D0X|rcsb pdb:5D0Z|rcsb pdb:5DKI|rcsb pdb:5DKJ|rcsb pdb:5FGD|rcsb pdb:3HYE|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:3MG0|rcsb pdb:3MG4|rcsb pdb:3MG6|rcsb pdb:3MG7|rcsb pdb:3MG8|rcsb pdb:3NZJ|rcsb pdb:3NZW|rcsb pdb:3NZX|rcsb pdb:3OEU|rcsb pdb:3OEV|rcsb pdb:3OKJ|rcsb pdb:3SDI|rcsb pdb:3SDK|rcsb pdb:3SHJ|rcsb pdb:3TDD|rcsb pdb:3UN4|rcsb pdb:3UN8|rcsb pdb:3WXR|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:4EU2|rcsb pdb:4FZC|rcsb pdb:4FZG|rcsb pdb:4G4S|rcsb pdb:4GK7|rcsb pdb:4HNP|rcsb pdb:4HRC|rcsb pdb:4HRD|rcsb pdb:4INR|rcsb pdb:4INT|rcsb pdb:4INU|rcsb pdb:4J70|rcsb pdb:4JSQ|rcsb pdb:4JSU|rcsb pdb:4JT0|rcsb pdb:4LQI|rcsb pdb:4LTC|rcsb pdb:4NNN|rcsb pdb:4NNW|rcsb pdb:4NO1|rcsb pdb:4NO6|rcsb pdb:4NO8|rcsb pdb:4NO9|rcsb pdb:5FGE|rcsb pdb:5FGF|rcsb pdb:5FGG|rcsb pdb:5FGH|rcsb pdb:5FGI|rcsb pdb:5FHS|rcsb pdb:5JHR|rcsb pdb:5JHS|rcsb pdb:5L52|rcsb pdb:5L54|rcsb pdb:5L55|rcsb pdb:5L5A|rcsb pdb:5L5B|rcsb pdb:5L5D|rcsb pdb:5L5E|rcsb pdb:5L5F|rcsb pdb:5L5H|rcsb pdb:5L5I|rcsb pdb:5L5J|rcsb pdb:5L5O|rcsb pdb:5L5P|rcsb pdb:5L5Q|rcsb pdb:5L5R|rcsb pdb:4Q1S|rcsb pdb:4QBY|rcsb pdb:4QLQ|rcsb pdb:4QLS|rcsb pdb:4QLT|rcsb pdb:4QLU|rcsb pdb:4QLV|rcsb pdb:4QUX|rcsb pdb:4QUY|rcsb pdb:4QV0|rcsb pdb:4QV1|rcsb pdb:4QV3|rcsb pdb:4QV4|rcsb pdb:4QV5|rcsb pdb:4QV6|rcsb pdb:4QV7|rcsb pdb:4QV8|rcsb pdb:4QV9|rcsb pdb:4QVL|ensemblfungi:YMR314W(gene)|ensemblfungi:YMR314W_mRNA(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0042175"(nuclear outer membrane-endoplasmic reticulum membrane network)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR035144|rcsb pdb:1FNT|rcsb pdb:1G0U|rcsb pdb:1G65|rcsb pdb:1JD2|rcsb pdb:1RYP|rcsb pdb:1Z7Q|rcsb pdb:2F16|rcsb pdb:2FAK|rcsb pdb:2GPL|rcsb pdb:2ZCY|rcsb pdb:3BDM|rcsb pdb:3D29|rcsb pdb:3DY3|rcsb pdb:3DY4|rcsb pdb:3E47|rcsb pdb:3GPJ|rcsb pdb:3GPT|rcsb pdb:3GPW|rcsb pdb:4QVM|rcsb pdb:4QVN|rcsb pdb:4QVP|rcsb pdb:4QVQ|rcsb pdb:4QVV|rcsb pdb:4QVW|rcsb pdb:4QVY|rcsb pdb:4QW0|rcsb pdb:4QW1|rcsb pdb:4QW3|rcsb pdb:4QW4|rcsb pdb:4QW5|rcsb pdb:4QW6|rcsb pdb:4QW7|rcsb pdb:4QWF|rcsb pdb:4QWG|rcsb pdb:4QWI|rcsb pdb:4QWJ|rcsb pdb:4QWK|rcsb pdb:4QWL|rcsb pdb:4QWR|rcsb pdb:4QWS|rcsb pdb:4QWU|rcsb pdb:4QWX|rcsb pdb:4QXJ|rcsb pdb:4QZ0|rcsb pdb:4QZ1|rcsb pdb:4QZ2|rcsb pdb:4QZ3|rcsb pdb:4QZ4|rcsb pdb:4QZ5|rcsb pdb:4QZ6|rcsb pdb:4QZ7|rcsb pdb:4QZW|rcsb pdb:4QZX|rcsb pdb:4QZZ|rcsb pdb:4R00|rcsb pdb:4R02|rcsb pdb:4R17|rcsb pdb:4R18|rcsb pdb:4RUR|rcsb pdb:4V7O|rcsb pdb:4X6Z|rcsb pdb:4Y69|rcsb pdb:4Y6A|rcsb pdb:4Y6V|rcsb pdb:4Y6Z|rcsb pdb:4Y70|rcsb pdb:4Y74|rcsb pdb:4Y75|rcsb pdb:4Y77|rcsb pdb:4Y78|rcsb pdb:4Y7W|rcsb pdb:5LTT|rcsb pdb:5M2B|rcsb pdb:5MP9|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5NIF|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6G7F|rcsb pdb:6G8M|rcsb pdb:6G8N|rcsb pdb:6GOP|rcsb pdb:6H39|rcsb pdb:6HTB|rcsb pdb:6HTC|rcsb pdb:6HTD|rcsb pdb:6HTP|rcsb pdb:6HTR|rcsb pdb:6HUB|rcsb pdb:6HUC|rcsb pdb:6HUQ|rcsb pdb:6HUU|rcsb pdb:6HUV|rcsb pdb:6HV3|rcsb pdb:6HV4|rcsb pdb:6HV5|rcsb pdb:6HV7|rcsb pdb:6HVA|rcsb pdb:6HVR|rcsb pdb:6HVS|rcsb pdb:6HVT|rcsb pdb:6HVU|rcsb pdb:6HVV|rcsb pdb:5L5S|rcsb pdb:5L5T|rcsb pdb:5L5U|rcsb pdb:5L5V|rcsb pdb:5L5W|rcsb pdb:5L5X|rcsb pdb:5L5Y|rcsb pdb:5L5Z|rcsb pdb:5L60|rcsb pdb:5L61|rcsb pdb:5L62|rcsb pdb:5L63|rcsb pdb:5L64|rcsb pdb:5L65|rcsb pdb:5L66|rcsb pdb:5L67|rcsb pdb:5L68|rcsb pdb:5L69|rcsb pdb:5L6A|rcsb pdb:5L6B|rcsb pdb:5L6C|rcsb pdb:5LAI|rcsb pdb:5LAJ|rcsb pdb:6HVW|rcsb pdb:6HVX|rcsb pdb:6HVY|rcsb pdb:6HW0|rcsb pdb:6HW3|rcsb pdb:6HW4|rcsb pdb:6HW5|rcsb pdb:6HW6|rcsb pdb:6HW7|rcsb pdb:6HW8|rcsb pdb:6HW9|rcsb pdb:6HWA|rcsb pdb:6HWB|rcsb pdb:6HWC|rcsb pdb:6HWD|rcsb pdb:6HWE|rcsb pdb:6HWF|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2X|rcsb pdb:6J30|rcsb pdb:6ZOU|rcsb pdb:6ZP6|rcsb pdb:6ZP8|rcsb pdb:7LS5|rcsb pdb:7LS6|rcsb pdb:7LSX|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|rcsb pdb:6J2Q|refseq:NP_014045.1|sgd:S000004931|mint:P40302|dip:DIP-1528N|sgd:YMR314W(identity)	-	-	crc64:C43CBCC1C6B9E39E	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:U1y/y52nnf7zQUCNQlqk7JDgXi49606	rogid:C9GPb0JAklkBz0t/YYqRMNEiQss559292	intact-crc:697D21B3D21A66CB|rigid:xJu4udRnt8uJIyFOJNW18Br9+yU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40302	uniprotkb:Q9H773	intact:EBI-13955|ensemblfungi:YMR314W|uniprotkb:D6W0E1	intact:EBI-723569|intact:EBI-1384169|ensembl:ENSP00000322524	psi-mi:psa6_yeast(display_long)|uniprotkb:PRE5(gene name)|psi-mi:PRE5(display_short)|uniprotkb:YMR314W(locus name)|uniprotkb:YM9924.06(orf name)|uniprotkb:Proteasome component PRE5(gene name synonym)|uniprotkb:Macropain subunit PRE5(gene name synonym)|uniprotkb:Proteinase YSCE subunit PRE5(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit PRE5(gene name synonym)	psi-mi:dctp1_human(display_long)|uniprotkb:DCTPP1(gene name)|psi-mi:DCTPP1(display_short)|uniprotkb:RS21C6(gene name synonym)|uniprotkb:CDA03(orf name)|uniprotkb:XTP3TPA(gene name synonym)|uniprotkb:Deoxycytidine-triphosphatase 1(gene name synonym)|uniprotkb:XTP3-transactivated gene A protein(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11530618|imex:IM-24995-867	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:4Y8T|rcsb pdb:4Y8U|rcsb pdb:4Y9Y|rcsb pdb:4Y9Z|rcsb pdb:4YA0|rcsb pdb:4YA1|rcsb pdb:4YA2|rcsb pdb:4YA3|rcsb pdb:4YA4|rcsb pdb:4YA5|rcsb pdb:4Y7X|rcsb pdb:4Y7Y|rcsb pdb:4Y80|rcsb pdb:4Y81|rcsb pdb:4Y82|rcsb pdb:4Y84|rcsb pdb:4Y8G|rcsb pdb:4Y8H|rcsb pdb:4Y8I|rcsb pdb:4Y8J|rcsb pdb:4Y8K|rcsb pdb:4Y8L|rcsb pdb:4Y8M|rcsb pdb:4Y8N|rcsb pdb:4Y8O|rcsb pdb:4Y8P|rcsb pdb:4Y8Q|rcsb pdb:4Y8R|rcsb pdb:4Y8S|rcsb pdb:5FG7|rcsb pdb:5FG9|rcsb pdb:5FGA|rcsb pdb:4YA7|rcsb pdb:4YA9|rcsb pdb:4Z1L|rcsb pdb:5A5B|rcsb pdb:5AHJ|rcsb pdb:5BOU|rcsb pdb:5BXL|rcsb pdb:5BXN|rcsb pdb:5CGF|rcsb pdb:5CGG|rcsb pdb:5CGH|rcsb pdb:5CGI|rcsb pdb:5CZ4|rcsb pdb:5CZ5|rcsb pdb:5CZ6|rcsb pdb:5CZ7|rcsb pdb:5CZ8|rcsb pdb:5CZ9|rcsb pdb:5CZA|rcsb pdb:5D0S|rcsb pdb:5D0T|rcsb pdb:5D0V|rcsb pdb:5D0W|rcsb pdb:5D0X|rcsb pdb:5D0Z|rcsb pdb:5DKI|rcsb pdb:5DKJ|rcsb pdb:5FGD|rcsb pdb:3HYE|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:3MG0|rcsb pdb:3MG4|rcsb pdb:3MG6|rcsb pdb:3MG7|rcsb pdb:3MG8|rcsb pdb:3NZJ|rcsb pdb:3NZW|rcsb pdb:3NZX|rcsb pdb:3OEU|rcsb pdb:3OEV|rcsb pdb:3OKJ|rcsb pdb:3SDI|rcsb pdb:3SDK|rcsb pdb:3SHJ|rcsb pdb:3TDD|rcsb pdb:3UN4|rcsb pdb:3UN8|rcsb pdb:3WXR|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:4EU2|rcsb pdb:4FZC|rcsb pdb:4FZG|rcsb pdb:4G4S|rcsb pdb:4GK7|rcsb pdb:4HNP|rcsb pdb:4HRC|rcsb pdb:4HRD|rcsb pdb:4INR|rcsb pdb:4INT|rcsb pdb:4INU|rcsb pdb:4J70|rcsb pdb:4JSQ|rcsb pdb:4JSU|rcsb pdb:4JT0|rcsb pdb:4LQI|rcsb pdb:4LTC|rcsb pdb:4NNN|rcsb pdb:4NNW|rcsb pdb:4NO1|rcsb pdb:4NO6|rcsb pdb:4NO8|rcsb pdb:4NO9|rcsb pdb:5FGE|rcsb pdb:5FGF|rcsb pdb:5FGG|rcsb pdb:5FGH|rcsb pdb:5FGI|rcsb pdb:5FHS|rcsb pdb:5JHR|rcsb pdb:5JHS|rcsb pdb:5L52|rcsb pdb:5L54|rcsb pdb:5L55|rcsb pdb:5L5A|rcsb pdb:5L5B|rcsb pdb:5L5D|rcsb pdb:5L5E|rcsb pdb:5L5F|rcsb pdb:5L5H|rcsb pdb:5L5I|rcsb pdb:5L5J|rcsb pdb:5L5O|rcsb pdb:5L5P|rcsb pdb:5L5Q|rcsb pdb:5L5R|rcsb pdb:4Q1S|rcsb pdb:4QBY|rcsb pdb:4QLQ|rcsb pdb:4QLS|rcsb pdb:4QLT|rcsb pdb:4QLU|rcsb pdb:4QLV|rcsb pdb:4QUX|rcsb pdb:4QUY|rcsb pdb:4QV0|rcsb pdb:4QV1|rcsb pdb:4QV3|rcsb pdb:4QV4|rcsb pdb:4QV5|rcsb pdb:4QV6|rcsb pdb:4QV7|rcsb pdb:4QV8|rcsb pdb:4QV9|rcsb pdb:4QVL|ensemblfungi:YMR314W(gene)|ensemblfungi:YMR314W_mRNA(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0042175"(nuclear outer membrane-endoplasmic reticulum membrane network)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR035144|rcsb pdb:1FNT|rcsb pdb:1G0U|rcsb pdb:1G65|rcsb pdb:1JD2|rcsb pdb:1RYP|rcsb pdb:1Z7Q|rcsb pdb:2F16|rcsb pdb:2FAK|rcsb pdb:2GPL|rcsb pdb:2ZCY|rcsb pdb:3BDM|rcsb pdb:3D29|rcsb pdb:3DY3|rcsb pdb:3DY4|rcsb pdb:3E47|rcsb pdb:3GPJ|rcsb pdb:3GPT|rcsb pdb:3GPW|rcsb pdb:4QVM|rcsb pdb:4QVN|rcsb pdb:4QVP|rcsb pdb:4QVQ|rcsb pdb:4QVV|rcsb pdb:4QVW|rcsb pdb:4QVY|rcsb pdb:4QW0|rcsb pdb:4QW1|rcsb pdb:4QW3|rcsb pdb:4QW4|rcsb pdb:4QW5|rcsb pdb:4QW6|rcsb pdb:4QW7|rcsb pdb:4QWF|rcsb pdb:4QWG|rcsb pdb:4QWI|rcsb pdb:4QWJ|rcsb pdb:4QWK|rcsb pdb:4QWL|rcsb pdb:4QWR|rcsb pdb:4QWS|rcsb pdb:4QWU|rcsb pdb:4QWX|rcsb pdb:4QXJ|rcsb pdb:4QZ0|rcsb pdb:4QZ1|rcsb pdb:4QZ2|rcsb pdb:4QZ3|rcsb pdb:4QZ4|rcsb pdb:4QZ5|rcsb pdb:4QZ6|rcsb pdb:4QZ7|rcsb pdb:4QZW|rcsb pdb:4QZX|rcsb pdb:4QZZ|rcsb pdb:4R00|rcsb pdb:4R02|rcsb pdb:4R17|rcsb pdb:4R18|rcsb pdb:4RUR|rcsb pdb:4V7O|rcsb pdb:4X6Z|rcsb pdb:4Y69|rcsb pdb:4Y6A|rcsb pdb:4Y6V|rcsb pdb:4Y6Z|rcsb pdb:4Y70|rcsb pdb:4Y74|rcsb pdb:4Y75|rcsb pdb:4Y77|rcsb pdb:4Y78|rcsb pdb:4Y7W|rcsb pdb:5LTT|rcsb pdb:5M2B|rcsb pdb:5MP9|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5NIF|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6G7F|rcsb pdb:6G8M|rcsb pdb:6G8N|rcsb pdb:6GOP|rcsb pdb:6H39|rcsb pdb:6HTB|rcsb pdb:6HTC|rcsb pdb:6HTD|rcsb pdb:6HTP|rcsb pdb:6HTR|rcsb pdb:6HUB|rcsb pdb:6HUC|rcsb pdb:6HUQ|rcsb pdb:6HUU|rcsb pdb:6HUV|rcsb pdb:6HV3|rcsb pdb:6HV4|rcsb pdb:6HV5|rcsb pdb:6HV7|rcsb pdb:6HVA|rcsb pdb:6HVR|rcsb pdb:6HVS|rcsb pdb:6HVT|rcsb pdb:6HVU|rcsb pdb:6HVV|rcsb pdb:5L5S|rcsb pdb:5L5T|rcsb pdb:5L5U|rcsb pdb:5L5V|rcsb pdb:5L5W|rcsb pdb:5L5X|rcsb pdb:5L5Y|rcsb pdb:5L5Z|rcsb pdb:5L60|rcsb pdb:5L61|rcsb pdb:5L62|rcsb pdb:5L63|rcsb pdb:5L64|rcsb pdb:5L65|rcsb pdb:5L66|rcsb pdb:5L67|rcsb pdb:5L68|rcsb pdb:5L69|rcsb pdb:5L6A|rcsb pdb:5L6B|rcsb pdb:5L6C|rcsb pdb:5LAI|rcsb pdb:5LAJ|rcsb pdb:6HVW|rcsb pdb:6HVX|rcsb pdb:6HVY|rcsb pdb:6HW0|rcsb pdb:6HW3|rcsb pdb:6HW4|rcsb pdb:6HW5|rcsb pdb:6HW6|rcsb pdb:6HW7|rcsb pdb:6HW8|rcsb pdb:6HW9|rcsb pdb:6HWA|rcsb pdb:6HWB|rcsb pdb:6HWC|rcsb pdb:6HWD|rcsb pdb:6HWE|rcsb pdb:6HWF|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2X|rcsb pdb:6J30|rcsb pdb:6ZOU|rcsb pdb:6ZP6|rcsb pdb:6ZP8|rcsb pdb:7LS5|rcsb pdb:7LS6|rcsb pdb:7LSX|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|rcsb pdb:6J2Q|refseq:NP_014045.1|sgd:S000004931|mint:P40302|dip:DIP-1528N|sgd:YMR314W(identity)	refseq:NP_077001.1|ensembl:ENST00000319285(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006253"(dCTP catabolic process)|go:"GO:0009143"(nucleoside triphosphate catabolic process)|go:"GO:0032556"(pyrimidine deoxyribonucleotide binding)|go:"GO:0042262"(DNA protection)|go:"GO:0042802"(identical protein binding)|go:"GO:0047429"(nucleoside-triphosphate diphosphatase activity)|go:"GO:0047840"(dCTP diphosphatase activity)|interpro:IPR025984|mint:Q9H773|reactome:R-HSA-499943|ensembl:ENSG00000179958(gene)|entrezgene/locuslink:79077(identity)	-	crc64:C43CBCC1C6B9E39E	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:C9GPb0JAklkBz0t/YYqRMNEiQss559292	rogid:4EfV2ZU2MgDiFXShthfualZnat09606	intact-crc:7A3C0B1393FFCBC3|rigid:mfoAdWwBictblqsBI2yhgBhCIQQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9H257-2	uniprotkb:P40302	intact:EBI-11530605|ensembl:ENSP00000360799	intact:EBI-13955|ensemblfungi:YMR314W|uniprotkb:D6W0E1	psi-mi:q9h257-2(display_long)|uniprotkb:CARD9(gene name)|psi-mi:CARD9(display_short)	psi-mi:psa6_yeast(display_long)|uniprotkb:PRE5(gene name)|psi-mi:PRE5(display_short)|uniprotkb:YMR314W(locus name)|uniprotkb:YM9924.06(orf name)|uniprotkb:Proteasome component PRE5(gene name synonym)|uniprotkb:Macropain subunit PRE5(gene name synonym)|uniprotkb:Proteinase YSCE subunit PRE5(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit PRE5(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11530609|imex:IM-24995-866	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-751319(isoform-parent)|uniprotkb:Q9H257-2(isoform-parent)|ensembl:ENSG00000187796(gene)|ensembl:ENST00000371734(transcript)|entrezgene/locuslink:64170(identity)	rcsb pdb:4Y8T|rcsb pdb:4Y8U|rcsb pdb:4Y9Y|rcsb pdb:4Y9Z|rcsb pdb:4YA0|rcsb pdb:4YA1|rcsb pdb:4YA2|rcsb pdb:4YA3|rcsb pdb:4YA4|rcsb pdb:4YA5|rcsb pdb:4Y7X|rcsb pdb:4Y7Y|rcsb pdb:4Y80|rcsb pdb:4Y81|rcsb pdb:4Y82|rcsb pdb:4Y84|rcsb pdb:4Y8G|rcsb pdb:4Y8H|rcsb pdb:4Y8I|rcsb pdb:4Y8J|rcsb pdb:4Y8K|rcsb pdb:4Y8L|rcsb pdb:4Y8M|rcsb pdb:4Y8N|rcsb pdb:4Y8O|rcsb pdb:4Y8P|rcsb pdb:4Y8Q|rcsb pdb:4Y8R|rcsb pdb:4Y8S|rcsb pdb:5FG7|rcsb pdb:5FG9|rcsb pdb:5FGA|rcsb pdb:4YA7|rcsb pdb:4YA9|rcsb pdb:4Z1L|rcsb pdb:5A5B|rcsb pdb:5AHJ|rcsb pdb:5BOU|rcsb pdb:5BXL|rcsb pdb:5BXN|rcsb pdb:5CGF|rcsb pdb:5CGG|rcsb pdb:5CGH|rcsb pdb:5CGI|rcsb pdb:5CZ4|rcsb pdb:5CZ5|rcsb pdb:5CZ6|rcsb pdb:5CZ7|rcsb pdb:5CZ8|rcsb pdb:5CZ9|rcsb pdb:5CZA|rcsb pdb:5D0S|rcsb pdb:5D0T|rcsb pdb:5D0V|rcsb pdb:5D0W|rcsb pdb:5D0X|rcsb pdb:5D0Z|rcsb pdb:5DKI|rcsb pdb:5DKJ|rcsb pdb:5FGD|rcsb pdb:3HYE|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:3MG0|rcsb pdb:3MG4|rcsb pdb:3MG6|rcsb pdb:3MG7|rcsb pdb:3MG8|rcsb pdb:3NZJ|rcsb pdb:3NZW|rcsb pdb:3NZX|rcsb pdb:3OEU|rcsb pdb:3OEV|rcsb pdb:3OKJ|rcsb pdb:3SDI|rcsb pdb:3SDK|rcsb pdb:3SHJ|rcsb pdb:3TDD|rcsb pdb:3UN4|rcsb pdb:3UN8|rcsb pdb:3WXR|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:4EU2|rcsb pdb:4FZC|rcsb pdb:4FZG|rcsb pdb:4G4S|rcsb pdb:4GK7|rcsb pdb:4HNP|rcsb pdb:4HRC|rcsb pdb:4HRD|rcsb pdb:4INR|rcsb pdb:4INT|rcsb pdb:4INU|rcsb pdb:4J70|rcsb pdb:4JSQ|rcsb pdb:4JSU|rcsb pdb:4JT0|rcsb pdb:4LQI|rcsb pdb:4LTC|rcsb pdb:4NNN|rcsb pdb:4NNW|rcsb pdb:4NO1|rcsb pdb:4NO6|rcsb pdb:4NO8|rcsb pdb:4NO9|rcsb pdb:5FGE|rcsb pdb:5FGF|rcsb pdb:5FGG|rcsb pdb:5FGH|rcsb pdb:5FGI|rcsb pdb:5FHS|rcsb pdb:5JHR|rcsb pdb:5JHS|rcsb pdb:5L52|rcsb pdb:5L54|rcsb pdb:5L55|rcsb pdb:5L5A|rcsb pdb:5L5B|rcsb pdb:5L5D|rcsb pdb:5L5E|rcsb pdb:5L5F|rcsb pdb:5L5H|rcsb pdb:5L5I|rcsb pdb:5L5J|rcsb pdb:5L5O|rcsb pdb:5L5P|rcsb pdb:5L5Q|rcsb pdb:5L5R|rcsb pdb:4Q1S|rcsb pdb:4QBY|rcsb pdb:4QLQ|rcsb pdb:4QLS|rcsb pdb:4QLT|rcsb pdb:4QLU|rcsb pdb:4QLV|rcsb pdb:4QUX|rcsb pdb:4QUY|rcsb pdb:4QV0|rcsb pdb:4QV1|rcsb pdb:4QV3|rcsb pdb:4QV4|rcsb pdb:4QV5|rcsb pdb:4QV6|rcsb pdb:4QV7|rcsb pdb:4QV8|rcsb pdb:4QV9|rcsb pdb:4QVL|ensemblfungi:YMR314W(gene)|ensemblfungi:YMR314W_mRNA(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0042175"(nuclear outer membrane-endoplasmic reticulum membrane network)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR035144|rcsb pdb:1FNT|rcsb pdb:1G0U|rcsb pdb:1G65|rcsb pdb:1JD2|rcsb pdb:1RYP|rcsb pdb:1Z7Q|rcsb pdb:2F16|rcsb pdb:2FAK|rcsb pdb:2GPL|rcsb pdb:2ZCY|rcsb pdb:3BDM|rcsb pdb:3D29|rcsb pdb:3DY3|rcsb pdb:3DY4|rcsb pdb:3E47|rcsb pdb:3GPJ|rcsb pdb:3GPT|rcsb pdb:3GPW|rcsb pdb:4QVM|rcsb pdb:4QVN|rcsb pdb:4QVP|rcsb pdb:4QVQ|rcsb pdb:4QVV|rcsb pdb:4QVW|rcsb pdb:4QVY|rcsb pdb:4QW0|rcsb pdb:4QW1|rcsb pdb:4QW3|rcsb pdb:4QW4|rcsb pdb:4QW5|rcsb pdb:4QW6|rcsb pdb:4QW7|rcsb pdb:4QWF|rcsb pdb:4QWG|rcsb pdb:4QWI|rcsb pdb:4QWJ|rcsb pdb:4QWK|rcsb pdb:4QWL|rcsb pdb:4QWR|rcsb pdb:4QWS|rcsb pdb:4QWU|rcsb pdb:4QWX|rcsb pdb:4QXJ|rcsb pdb:4QZ0|rcsb pdb:4QZ1|rcsb pdb:4QZ2|rcsb pdb:4QZ3|rcsb pdb:4QZ4|rcsb pdb:4QZ5|rcsb pdb:4QZ6|rcsb pdb:4QZ7|rcsb pdb:4QZW|rcsb pdb:4QZX|rcsb pdb:4QZZ|rcsb pdb:4R00|rcsb pdb:4R02|rcsb pdb:4R17|rcsb pdb:4R18|rcsb pdb:4RUR|rcsb pdb:4V7O|rcsb pdb:4X6Z|rcsb pdb:4Y69|rcsb pdb:4Y6A|rcsb pdb:4Y6V|rcsb pdb:4Y6Z|rcsb pdb:4Y70|rcsb pdb:4Y74|rcsb pdb:4Y75|rcsb pdb:4Y77|rcsb pdb:4Y78|rcsb pdb:4Y7W|rcsb pdb:5LTT|rcsb pdb:5M2B|rcsb pdb:5MP9|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5NIF|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6G7F|rcsb pdb:6G8M|rcsb pdb:6G8N|rcsb pdb:6GOP|rcsb pdb:6H39|rcsb pdb:6HTB|rcsb pdb:6HTC|rcsb pdb:6HTD|rcsb pdb:6HTP|rcsb pdb:6HTR|rcsb pdb:6HUB|rcsb pdb:6HUC|rcsb pdb:6HUQ|rcsb pdb:6HUU|rcsb pdb:6HUV|rcsb pdb:6HV3|rcsb pdb:6HV4|rcsb pdb:6HV5|rcsb pdb:6HV7|rcsb pdb:6HVA|rcsb pdb:6HVR|rcsb pdb:6HVS|rcsb pdb:6HVT|rcsb pdb:6HVU|rcsb pdb:6HVV|rcsb pdb:5L5S|rcsb pdb:5L5T|rcsb pdb:5L5U|rcsb pdb:5L5V|rcsb pdb:5L5W|rcsb pdb:5L5X|rcsb pdb:5L5Y|rcsb pdb:5L5Z|rcsb pdb:5L60|rcsb pdb:5L61|rcsb pdb:5L62|rcsb pdb:5L63|rcsb pdb:5L64|rcsb pdb:5L65|rcsb pdb:5L66|rcsb pdb:5L67|rcsb pdb:5L68|rcsb pdb:5L69|rcsb pdb:5L6A|rcsb pdb:5L6B|rcsb pdb:5L6C|rcsb pdb:5LAI|rcsb pdb:5LAJ|rcsb pdb:6HVW|rcsb pdb:6HVX|rcsb pdb:6HVY|rcsb pdb:6HW0|rcsb pdb:6HW3|rcsb pdb:6HW4|rcsb pdb:6HW5|rcsb pdb:6HW6|rcsb pdb:6HW7|rcsb pdb:6HW8|rcsb pdb:6HW9|rcsb pdb:6HWA|rcsb pdb:6HWB|rcsb pdb:6HWC|rcsb pdb:6HWD|rcsb pdb:6HWE|rcsb pdb:6HWF|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2X|rcsb pdb:6J30|rcsb pdb:6ZOU|rcsb pdb:6ZP6|rcsb pdb:6ZP8|rcsb pdb:7LS5|rcsb pdb:7LS6|rcsb pdb:7LSX|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|rcsb pdb:6J2Q|refseq:NP_014045.1|sgd:S000004931|mint:P40302|dip:DIP-1528N|sgd:YMR314W(identity)	-	isoform-comment:No experimental confirmation available.	crc64:C43CBCC1C6B9E39E	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:ZXH7B3K5NAzF1LZaeK50ciH1RTE9606	rogid:C9GPb0JAklkBz0t/YYqRMNEiQss559292	intact-crc:0F67A8E48C6F085C|rigid:VeHZM7S8tZjQXJfmOgOF/t5Ecz4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40312	uniprotkb:Q8N6L0	intact:EBI-2095239|uniprotkb:D6W170|ensemblfungi:YNL111C	intact:EBI-749265|uniprotkb:Q96MC3|ensembl:ENSP00000404220	psi-mi:cyb5_yeast(display_long)|uniprotkb:N1949(orf name)|uniprotkb:YNL111C(locus name)|uniprotkb:CYB5(gene name)|psi-mi:CYB5(display_short)	psi-mi:kash5_human(display_long)|uniprotkb:KASH5(gene name)|psi-mi:KASH5(display_short)|uniprotkb:CCDC155(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 155(gene name synonym)|uniprotkb:KASH domain-containing protein 5(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11530656|imex:IM-24995-871	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005055|interpro:IPR001199(Cytochrome b5)|interpro:IPR018506|refseq:NP_014288.3|mint:P40312|interpro:IPR036400|ensemblfungi:YNL111C(gene)|ensemblfungi:YNL111C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0009055"(electron transfer activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016126"(sterol biosynthetic process)|go:"GO:0020037"(heme binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|reactome:R-SCE-196836|reactome:R-SCE-9609523|sgd:YNL111C(identity)	refseq:NP_653289.3|ensembl:ENSG00000161609(gene)|ensembl:ENST00000447857(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034397"(telomere localization)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051225"(spindle assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0090172"(microtubule cytoskeleton organization involved in homologous chromosome segregation)|go:"GO:0090220"(chromosome localization to nuclear envelope involved in homologous chromosome segregation)|go:"GO:0090619"(meiotic spindle pole)|interpro:IPR011992(EF-Hand type)|interpro:IPR028168|interpro:IPR028170|interpro:IPR039508|mint:Q8N6L0|rcsb pdb:6R2I|rcsb pdb:6WMF|entrezgene/locuslink:147872(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:aB5Ul8scxDg0gRGx3rkZwTtfNM4559292	rogid:Wl9L7AcvDHCZuKjYLn8QgGIbZTc9606	intact-crc:D3B750DF544B2C4B|rigid:8eqAa6AQQ/XG1Q8umWLNxw2xuiw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8NEU8	uniprotkb:P40303	intact:EBI-741261|ensembl:ENSP00000258530|uniprotkb:Q8N4R7|uniprotkb:Q9NVL2|uniprotkb:B7Z411|uniprotkb:B7Z4B0|uniprotkb:F5GZG0|uniprotkb:F8W1P5	intact:EBI-13980|ensemblfungi:YOL038W|uniprotkb:D6W229	psi-mi:dp13b_human(display_long)|uniprotkb:Adapter protein containing PH domain, PTB domain and leucine zipper motif 2(gene name synonym)|uniprotkb:APPL2(gene name)|psi-mi:APPL2(display_short)|uniprotkb:DIP13B(gene name synonym)	psi-mi:psa4_yeast(display_long)|uniprotkb:PRE6(gene name)|psi-mi:PRE6(display_short)|uniprotkb:YOL038W(locus name)|uniprotkb:Proteasome component PRE6(gene name synonym)|uniprotkb:Macropain subunit PRE6(gene name synonym)|uniprotkb:Proteinase YSCE subunit PRE6(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit PRE6(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11530647|imex:IM-24995-870	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0002024"(diet induced thermogenesis)|go:"GO:0005634"(nucleus)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0009631"(cold acclimation)|go:"GO:0010008"(endosome membrane)|go:"GO:0010762"(regulation of fibroblast migration)|go:"GO:0016020"(membrane)|go:"GO:0023052"(signaling)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032009"(early phagosome)|go:"GO:0032587"(ruffle membrane)|go:"GO:0033211"(adiponectin-activated signaling pathway)|go:"GO:0034143"(regulation of toll-like receptor 4 signaling pathway)|go:"GO:0035091"(phosphatidylinositol binding)|ensembl:ENSG00000136044(gene)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0036186"(early phagosome membrane)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|ensembl:ENST00000258530(transcript)|go:"GO:0044354"(macropinosome)|go:"GO:0001726"(ruffle)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000178"(negative regulation of neural precursor cell proliferation)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR027267|mint:Q8NEU8|rcsb pdb:4H8S|rcsb pdb:5C5B|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0046322"(negative regulation of fatty acid oxidation)|go:"GO:0046325"(negative regulation of glucose import)|go:"GO:0050768"(negative regulation of neurogenesis)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060100"(positive regulation of phagocytosis, engulfment)|go:"GO:0070062"(extracellular exosome)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1900016"(negative regulation of cytokine production involved in inflammatory response)|go:"GO:1900077"(negative regulation of cellular response to insulin stimulus)|go:"GO:1905303"(positive regulation of macropinocytosis)|go:"GO:1905451"(positive regulation of Fc-gamma receptor signaling pathway involved in phagocytosis)|refseq:NP_060641.2|refseq:XP_016875042.1|refseq:XP_016875041.1|refseq:NP_001238833.1|refseq:NP_001238834.1|entrezgene/locuslink:55198(identity)	ensemblfungi:YOL038W(gene)|ensemblfungi:YOL038W_mRNA(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0042175"(nuclear outer membrane-endoplasmic reticulum membrane network)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023332|interpro:IPR029055|rcsb pdb:1FNT|rcsb pdb:1G0U|rcsb pdb:1G65|rcsb pdb:1JD2|rcsb pdb:1RYP|rcsb pdb:1Z7Q|rcsb pdb:2F16|rcsb pdb:2FAK|rcsb pdb:2GPL|rcsb pdb:2ZCY|rcsb pdb:3BDM|rcsb pdb:3D29|rcsb pdb:3DY3|rcsb pdb:3DY4|rcsb pdb:4QZ1|rcsb pdb:4QZ2|rcsb pdb:4QZ3|rcsb pdb:4QZ4|rcsb pdb:4QZ5|rcsb pdb:4QZ6|rcsb pdb:4QZ7|rcsb pdb:4QZW|rcsb pdb:4QZX|rcsb pdb:4QZZ|rcsb pdb:4R00|rcsb pdb:4R02|rcsb pdb:4R17|rcsb pdb:4R18|rcsb pdb:4RUR|rcsb pdb:4V7O|rcsb pdb:4X6Z|rcsb pdb:4Y69|rcsb pdb:4Y6A|rcsb pdb:4Y6V|rcsb pdb:4Y6Z|rcsb pdb:4Y70|rcsb pdb:4Y74|rcsb pdb:4Y75|rcsb pdb:4Y77|rcsb pdb:4Y78|rcsb pdb:4Y7W|rcsb pdb:4Y7X|rcsb pdb:4Y7Y|rcsb pdb:4Y80|rcsb pdb:4QZ0|rcsb pdb:4Y81|rcsb pdb:4Y82|rcsb pdb:4Y84|rcsb pdb:4Y8H|rcsb pdb:4Y8I|rcsb pdb:4Y8J|rcsb pdb:4Y8K|rcsb pdb:4Y8L|rcsb pdb:4Y8M|rcsb pdb:4Y8N|rcsb pdb:4Y8O|rcsb pdb:4Y8P|rcsb pdb:4Y8Q|rcsb pdb:4Y8R|rcsb pdb:4Y8S|rcsb pdb:4Y8T|rcsb pdb:4Y8U|rcsb pdb:4Y9Y|rcsb pdb:4Y9Z|rcsb pdb:4YA0|rcsb pdb:4YA1|rcsb pdb:4YA2|rcsb pdb:4YA3|rcsb pdb:4Y8G|rcsb pdb:4YA4|rcsb pdb:4YA5|rcsb pdb:4YA7|rcsb pdb:4YA9|rcsb pdb:4Z1L|rcsb pdb:5A5B|rcsb pdb:5AHJ|rcsb pdb:5BOU|rcsb pdb:5BXN|rcsb pdb:5CGF|rcsb pdb:5CGG|rcsb pdb:5CGH|rcsb pdb:5CGI|rcsb pdb:5CZ4|rcsb pdb:5CZ5|rcsb pdb:5CZ6|rcsb pdb:5CZ7|rcsb pdb:5CZ8|rcsb pdb:5CZ9|rcsb pdb:5CZA|rcsb pdb:5D0S|rcsb pdb:5D0T|rcsb pdb:5D0V|rcsb pdb:5D0W|rcsb pdb:5D0X|rcsb pdb:5BXL|rcsb pdb:5D0Z|rcsb pdb:5DKI|rcsb pdb:5DKJ|rcsb pdb:5FG9|rcsb pdb:5FGA|rcsb pdb:5FGD|rcsb pdb:5FGE|rcsb pdb:5FGF|rcsb pdb:5FGG|rcsb pdb:5FGH|rcsb pdb:5FG7|rcsb pdb:5FGI|rcsb pdb:5FHS|rcsb pdb:5JHR|rcsb pdb:5JHS|rcsb pdb:5L52|rcsb pdb:5L54|rcsb pdb:5L55|rcsb pdb:5L5A|rcsb pdb:5L5B|rcsb pdb:5L5D|rcsb pdb:5L5E|rcsb pdb:5L5F|rcsb pdb:5L5H|rcsb pdb:5L5I|rcsb pdb:5L5J|rcsb pdb:5L5O|rcsb pdb:5L5P|rcsb pdb:5L5Q|rcsb pdb:5L5R|rcsb pdb:5L5S|rcsb pdb:5L5T|rcsb pdb:5L5U|rcsb pdb:5L5V|rcsb pdb:5L5W|rcsb pdb:5L5X|rcsb pdb:5L5Y|rcsb pdb:5L5Z|rcsb pdb:5L60|rcsb pdb:5L61|rcsb pdb:5L62|rcsb pdb:5L63|rcsb pdb:5L64|rcsb pdb:5L65|rcsb pdb:5L66|rcsb pdb:5L67|rcsb pdb:5L68|rcsb pdb:5L69|rcsb pdb:5L6A|rcsb pdb:5L6B|rcsb pdb:5LAI|rcsb pdb:5LAJ|rcsb pdb:5LTT|rcsb pdb:5M2B|rcsb pdb:5MP9|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5NIF|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:5L6C|rcsb pdb:6FVW|rcsb pdb:6FVY|rcsb pdb:6G7F|rcsb pdb:6G8M|rcsb pdb:6G8N|rcsb pdb:6GOP|rcsb pdb:6H39|rcsb pdb:6HTB|rcsb pdb:6HTC|rcsb pdb:6HTD|rcsb pdb:6HTP|rcsb pdb:6HTR|rcsb pdb:6HUB|rcsb pdb:6HUC|rcsb pdb:6HUQ|rcsb pdb:6FVX|rcsb pdb:6HUU|rcsb pdb:6HUV|rcsb pdb:6HV3|rcsb pdb:6HV4|rcsb pdb:6HV5|rcsb pdb:6HV7|rcsb pdb:6HVA|rcsb pdb:6HVR|rcsb pdb:6HVS|rcsb pdb:6HVT|rcsb pdb:6HVU|rcsb pdb:6HVV|rcsb pdb:6HVW|rcsb pdb:6HVX|rcsb pdb:6HVY|rcsb pdb:6HW0|rcsb pdb:6HW3|rcsb pdb:6HW4|rcsb pdb:6HW5|rcsb pdb:6HW6|rcsb pdb:6HW7|rcsb pdb:6HW8|rcsb pdb:6HW9|rcsb pdb:6HWA|rcsb pdb:6HWB|rcsb pdb:6HWC|rcsb pdb:6HWE|rcsb pdb:6HWF|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6HWD|rcsb pdb:6J2X|rcsb pdb:6J30|rcsb pdb:6ZOU|rcsb pdb:6ZP6|rcsb pdb:6ZP8|rcsb pdb:7LS5|rcsb pdb:7LS6|rcsb pdb:7LSX|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|rcsb pdb:3E47|rcsb pdb:3GPJ|rcsb pdb:3GPT|rcsb pdb:3GPW|rcsb pdb:3HYE|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:3MG0|rcsb pdb:3MG4|rcsb pdb:3MG6|rcsb pdb:3MG7|rcsb pdb:3MG8|rcsb pdb:3NZJ|rcsb pdb:3NZW|rcsb pdb:3NZX|rcsb pdb:3OEU|rcsb pdb:3OEV|rcsb pdb:3OKJ|rcsb pdb:3SDI|rcsb pdb:3SDK|rcsb pdb:3SHJ|rcsb pdb:3TDD|rcsb pdb:3UN4|rcsb pdb:3UN8|rcsb pdb:3WXR|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:4EU2|rcsb pdb:4FZC|rcsb pdb:4FZG|rcsb pdb:4G4S|rcsb pdb:4GK7|rcsb pdb:4HRC|rcsb pdb:4HRD|rcsb pdb:4INR|rcsb pdb:4INT|rcsb pdb:4INU|rcsb pdb:4J70|rcsb pdb:4JSQ|rcsb pdb:4JSU|rcsb pdb:4JT0|rcsb pdb:4LQI|rcsb pdb:4LTC|rcsb pdb:4NNN|rcsb pdb:4NNW|rcsb pdb:4NO1|rcsb pdb:4HNP|rcsb pdb:4NO6|rcsb pdb:4NO8|rcsb pdb:4NO9|rcsb pdb:4Q1S|rcsb pdb:4QBY|rcsb pdb:4QLQ|rcsb pdb:4QLS|rcsb pdb:4QLT|rcsb pdb:4QLU|rcsb pdb:4QLV|rcsb pdb:4QUX|rcsb pdb:4QUY|rcsb pdb:4QV1|rcsb pdb:4QV3|rcsb pdb:4QV4|rcsb pdb:4QV5|rcsb pdb:4QV6|rcsb pdb:4QV7|rcsb pdb:4QV8|rcsb pdb:4QV9|rcsb pdb:4QVL|rcsb pdb:4QVM|rcsb pdb:4QVN|rcsb pdb:4QVP|rcsb pdb:4QVQ|rcsb pdb:4QVV|rcsb pdb:4QVW|rcsb pdb:4QVY|rcsb pdb:4QW0|rcsb pdb:4QW1|rcsb pdb:4QW3|rcsb pdb:4QW4|rcsb pdb:4QW5|rcsb pdb:4QW6|rcsb pdb:4QW7|rcsb pdb:4QWF|rcsb pdb:4QWG|rcsb pdb:4QV0|rcsb pdb:4QWI|rcsb pdb:4QWJ|rcsb pdb:4QWK|rcsb pdb:4QWL|rcsb pdb:4QWR|rcsb pdb:4QWS|rcsb pdb:4QWU|rcsb pdb:4QWX|rcsb pdb:4QXJ|refseq:NP_014604.1|sgd:S000005398|mint:P40303|dip:DIP-4844N|sgd:YOL038W(identity)	-	-	crc64:73AEE63B836E618A	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:8T+Y5phqYZ2On/CsfVVsOChSJNM9606	rogid:G8IQr0G8FhiWc0DYUlh3vecHQsU559292	intact-crc:B493D0D98C540872|rigid:tKdwVIRRkDlkwHnZtCmlUdnHbM4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40303	uniprotkb:Q08379	intact:EBI-13980|ensemblfungi:YOL038W|uniprotkb:D6W229	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	psi-mi:psa4_yeast(display_long)|uniprotkb:PRE6(gene name)|psi-mi:PRE6(display_short)|uniprotkb:YOL038W(locus name)|uniprotkb:Proteasome component PRE6(gene name synonym)|uniprotkb:Macropain subunit PRE6(gene name synonym)|uniprotkb:Proteinase YSCE subunit PRE6(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit PRE6(gene name synonym)	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11530636|imex:IM-24995-869	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YOL038W(gene)|ensemblfungi:YOL038W_mRNA(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0042175"(nuclear outer membrane-endoplasmic reticulum membrane network)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023332|interpro:IPR029055|rcsb pdb:1FNT|rcsb pdb:1G0U|rcsb pdb:1G65|rcsb pdb:1JD2|rcsb pdb:1RYP|rcsb pdb:1Z7Q|rcsb pdb:2F16|rcsb pdb:2FAK|rcsb pdb:2GPL|rcsb pdb:2ZCY|rcsb pdb:3BDM|rcsb pdb:3D29|rcsb pdb:3DY3|rcsb pdb:3DY4|rcsb pdb:4QZ1|rcsb pdb:4QZ2|rcsb pdb:4QZ3|rcsb pdb:4QZ4|rcsb pdb:4QZ5|rcsb pdb:4QZ6|rcsb pdb:4QZ7|rcsb pdb:4QZW|rcsb pdb:4QZX|rcsb pdb:4QZZ|rcsb pdb:4R00|rcsb pdb:4R02|rcsb pdb:4R17|rcsb pdb:4R18|rcsb pdb:4RUR|rcsb pdb:4V7O|rcsb pdb:4X6Z|rcsb pdb:4Y69|rcsb pdb:4Y6A|rcsb pdb:4Y6V|rcsb pdb:4Y6Z|rcsb pdb:4Y70|rcsb pdb:4Y74|rcsb pdb:4Y75|rcsb pdb:4Y77|rcsb pdb:4Y78|rcsb pdb:4Y7W|rcsb pdb:4Y7X|rcsb pdb:4Y7Y|rcsb pdb:4Y80|rcsb pdb:4QZ0|rcsb pdb:4Y81|rcsb pdb:4Y82|rcsb pdb:4Y84|rcsb pdb:4Y8H|rcsb pdb:4Y8I|rcsb pdb:4Y8J|rcsb pdb:4Y8K|rcsb pdb:4Y8L|rcsb pdb:4Y8M|rcsb pdb:4Y8N|rcsb pdb:4Y8O|rcsb pdb:4Y8P|rcsb pdb:4Y8Q|rcsb pdb:4Y8R|rcsb pdb:4Y8S|rcsb pdb:4Y8T|rcsb pdb:4Y8U|rcsb pdb:4Y9Y|rcsb pdb:4Y9Z|rcsb pdb:4YA0|rcsb pdb:4YA1|rcsb pdb:4YA2|rcsb pdb:4YA3|rcsb pdb:4Y8G|rcsb pdb:4YA4|rcsb pdb:4YA5|rcsb pdb:4YA7|rcsb pdb:4YA9|rcsb pdb:4Z1L|rcsb pdb:5A5B|rcsb pdb:5AHJ|rcsb pdb:5BOU|rcsb pdb:5BXN|rcsb pdb:5CGF|rcsb pdb:5CGG|rcsb pdb:5CGH|rcsb pdb:5CGI|rcsb pdb:5CZ4|rcsb pdb:5CZ5|rcsb pdb:5CZ6|rcsb pdb:5CZ7|rcsb pdb:5CZ8|rcsb pdb:5CZ9|rcsb pdb:5CZA|rcsb pdb:5D0S|rcsb pdb:5D0T|rcsb pdb:5D0V|rcsb pdb:5D0W|rcsb pdb:5D0X|rcsb pdb:5BXL|rcsb pdb:5D0Z|rcsb pdb:5DKI|rcsb pdb:5DKJ|rcsb pdb:5FG9|rcsb pdb:5FGA|rcsb pdb:5FGD|rcsb pdb:5FGE|rcsb pdb:5FGF|rcsb pdb:5FGG|rcsb pdb:5FGH|rcsb pdb:5FG7|rcsb pdb:5FGI|rcsb pdb:5FHS|rcsb pdb:5JHR|rcsb pdb:5JHS|rcsb pdb:5L52|rcsb pdb:5L54|rcsb pdb:5L55|rcsb pdb:5L5A|rcsb pdb:5L5B|rcsb pdb:5L5D|rcsb pdb:5L5E|rcsb pdb:5L5F|rcsb pdb:5L5H|rcsb pdb:5L5I|rcsb pdb:5L5J|rcsb pdb:5L5O|rcsb pdb:5L5P|rcsb pdb:5L5Q|rcsb pdb:5L5R|rcsb pdb:5L5S|rcsb pdb:5L5T|rcsb pdb:5L5U|rcsb pdb:5L5V|rcsb pdb:5L5W|rcsb pdb:5L5X|rcsb pdb:5L5Y|rcsb pdb:5L5Z|rcsb pdb:5L60|rcsb pdb:5L61|rcsb pdb:5L62|rcsb pdb:5L63|rcsb pdb:5L64|rcsb pdb:5L65|rcsb pdb:5L66|rcsb pdb:5L67|rcsb pdb:5L68|rcsb pdb:5L69|rcsb pdb:5L6A|rcsb pdb:5L6B|rcsb pdb:5LAI|rcsb pdb:5LAJ|rcsb pdb:5LTT|rcsb pdb:5M2B|rcsb pdb:5MP9|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5NIF|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:5L6C|rcsb pdb:6FVW|rcsb pdb:6FVY|rcsb pdb:6G7F|rcsb pdb:6G8M|rcsb pdb:6G8N|rcsb pdb:6GOP|rcsb pdb:6H39|rcsb pdb:6HTB|rcsb pdb:6HTC|rcsb pdb:6HTD|rcsb pdb:6HTP|rcsb pdb:6HTR|rcsb pdb:6HUB|rcsb pdb:6HUC|rcsb pdb:6HUQ|rcsb pdb:6FVX|rcsb pdb:6HUU|rcsb pdb:6HUV|rcsb pdb:6HV3|rcsb pdb:6HV4|rcsb pdb:6HV5|rcsb pdb:6HV7|rcsb pdb:6HVA|rcsb pdb:6HVR|rcsb pdb:6HVS|rcsb pdb:6HVT|rcsb pdb:6HVU|rcsb pdb:6HVV|rcsb pdb:6HVW|rcsb pdb:6HVX|rcsb pdb:6HVY|rcsb pdb:6HW0|rcsb pdb:6HW3|rcsb pdb:6HW4|rcsb pdb:6HW5|rcsb pdb:6HW6|rcsb pdb:6HW7|rcsb pdb:6HW8|rcsb pdb:6HW9|rcsb pdb:6HWA|rcsb pdb:6HWB|rcsb pdb:6HWC|rcsb pdb:6HWE|rcsb pdb:6HWF|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6HWD|rcsb pdb:6J2X|rcsb pdb:6J30|rcsb pdb:6ZOU|rcsb pdb:6ZP6|rcsb pdb:6ZP8|rcsb pdb:7LS5|rcsb pdb:7LS6|rcsb pdb:7LSX|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|rcsb pdb:3E47|rcsb pdb:3GPJ|rcsb pdb:3GPT|rcsb pdb:3GPW|rcsb pdb:3HYE|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:3MG0|rcsb pdb:3MG4|rcsb pdb:3MG6|rcsb pdb:3MG7|rcsb pdb:3MG8|rcsb pdb:3NZJ|rcsb pdb:3NZW|rcsb pdb:3NZX|rcsb pdb:3OEU|rcsb pdb:3OEV|rcsb pdb:3OKJ|rcsb pdb:3SDI|rcsb pdb:3SDK|rcsb pdb:3SHJ|rcsb pdb:3TDD|rcsb pdb:3UN4|rcsb pdb:3UN8|rcsb pdb:3WXR|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:4EU2|rcsb pdb:4FZC|rcsb pdb:4FZG|rcsb pdb:4G4S|rcsb pdb:4GK7|rcsb pdb:4HRC|rcsb pdb:4HRD|rcsb pdb:4INR|rcsb pdb:4INT|rcsb pdb:4INU|rcsb pdb:4J70|rcsb pdb:4JSQ|rcsb pdb:4JSU|rcsb pdb:4JT0|rcsb pdb:4LQI|rcsb pdb:4LTC|rcsb pdb:4NNN|rcsb pdb:4NNW|rcsb pdb:4NO1|rcsb pdb:4HNP|rcsb pdb:4NO6|rcsb pdb:4NO8|rcsb pdb:4NO9|rcsb pdb:4Q1S|rcsb pdb:4QBY|rcsb pdb:4QLQ|rcsb pdb:4QLS|rcsb pdb:4QLT|rcsb pdb:4QLU|rcsb pdb:4QLV|rcsb pdb:4QUX|rcsb pdb:4QUY|rcsb pdb:4QV1|rcsb pdb:4QV3|rcsb pdb:4QV4|rcsb pdb:4QV5|rcsb pdb:4QV6|rcsb pdb:4QV7|rcsb pdb:4QV8|rcsb pdb:4QV9|rcsb pdb:4QVL|rcsb pdb:4QVM|rcsb pdb:4QVN|rcsb pdb:4QVP|rcsb pdb:4QVQ|rcsb pdb:4QVV|rcsb pdb:4QVW|rcsb pdb:4QVY|rcsb pdb:4QW0|rcsb pdb:4QW1|rcsb pdb:4QW3|rcsb pdb:4QW4|rcsb pdb:4QW5|rcsb pdb:4QW6|rcsb pdb:4QW7|rcsb pdb:4QWF|rcsb pdb:4QWG|rcsb pdb:4QV0|rcsb pdb:4QWI|rcsb pdb:4QWJ|rcsb pdb:4QWK|rcsb pdb:4QWL|rcsb pdb:4QWR|rcsb pdb:4QWS|rcsb pdb:4QWU|rcsb pdb:4QWX|rcsb pdb:4QXJ|refseq:NP_014604.1|sgd:S000005398|mint:P40303|dip:DIP-4844N|sgd:YOL038W(identity)	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N|entrezgene/locuslink:2801(identity)	-	crc64:73AEE63B836E618A	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2017/05/26	rogid:G8IQr0G8FhiWc0DYUlh3vecHQsU559292	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	intact-crc:EC81503ABD5171D1|rigid:ISh8x9sKRumZ+m46aodWbR7ddg8	false	-	sufficient binding region:383-1002	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O14641	uniprotkb:P40325	intact:EBI-740850|ensembl:ENSP00000005340|uniprotkb:Q53XM0|uniprotkb:D3DTN3	intact:EBI-23614|uniprotkb:D6VV46|ensemblfungi:YGR268C	psi-mi:dvl2_human(display_long)|uniprotkb:DSH homolog 2(gene name synonym)|uniprotkb:DVL2(gene name)|psi-mi:DVL2(display_short)	psi-mi:hua1_yeast(display_long)|uniprotkb:HUA1(gene name)|psi-mi:HUA1(display_short)|uniprotkb:YGR268C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11530685|imex:IM-24995-874	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004413.1|ensembl:ENSG00000004975(gene)|ensembl:ENST00000005340(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005109"(frizzled binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0007507"(heart development)|go:"GO:0016235"(aggresome)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044340"(canonical Wnt signaling pathway involved in regulation of cell proliferation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0150012"(positive regulation of neuron projection arborization)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008341(Dishevelled-2 region)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:O14641|rcsb pdb:2REY|rcsb pdb:3CBX|rcsb pdb:3CBY|rcsb pdb:3CBZ|rcsb pdb:3CC0|rcsb pdb:4WIP|rcsb pdb:5LNP|rcsb pdb:5SUY|rcsb pdb:5SUZ|rcsb pdb:6IW3|rcsb pdb:6JCK|reactome:R-HSA-201681|reactome:R-HSA-201688|reactome:R-HSA-2028269|reactome:R-HSA-4086400|reactome:R-HSA-4608870|reactome:R-HSA-4641258|reactome:R-HSA-4641262|reactome:R-HSA-5099900|reactome:R-HSA-5368598|reactome:R-HSA-5663220|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9673324|ensembl:ENSP00000005340|dip:DIP-34433N|entrezgene/locuslink:1856(identity)	sgd:S000003500|refseq:NP_011784.3|dip:DIP-1987N|ensemblfungi:YGR268C(gene)|ensemblfungi:YGR268C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|interpro:IPR038910|sgd:YGR268C(identity)	-	-	crc64:78029FD484168793	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:2Vdc8oRnT4Mz/j+EXQXrL3AszOc9606	rogid:xliNG9XUWbYRd0Nbu+xzCgxNrAs559292	intact-crc:DD076888234C01BF|rigid:jooQ7Ge+kEOIeZpv8+uU/HTP9Gw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O00308	uniprotkb:P40325	intact:EBI-743923|uniprotkb:H3BRF3|uniprotkb:Q6ZTQ5|uniprotkb:A6NEP1|uniprotkb:Q96CZ2|uniprotkb:Q9BWN6|uniprotkb:B2R706|uniprotkb:B4DTL5|uniprotkb:F5H213|uniprotkb:I3RSG8|ensembl:ENSP00000352069	intact:EBI-23614|uniprotkb:D6VV46|ensemblfungi:YGR268C	psi-mi:wwp2_human(display_long)|uniprotkb:WW domain-containing protein 2(gene name synonym)|uniprotkb:Atrophin-1-interacting protein 2(gene name synonym)|uniprotkb:WWP2(gene name)|psi-mi:WWP2(display_short)|uniprotkb:HECT-type E3 ubiquitin transferase WWP2(gene name synonym)	psi-mi:hua1_yeast(display_long)|uniprotkb:HUA1(gene name)|psi-mi:HUA1(display_short)|uniprotkb:YGR268C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11530676|imex:IM-24995-873	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_008945.2|refseq:NP_001257383.1|refseq:NP_001257384.1|refseq:XP_011521125.1|refseq:XP_011521127.1|refseq:XP_011521128.1|refseq:NP_001257382.1|refseq:NP_955456.1|refseq:XP_016878368.1|refseq:XP_016878369.1|refseq:XP_016878370.1|ensembl:ENSG00000198373(gene)|ensembl:ENST00000359154(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006858"(extracellular transport)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032410"(negative regulation of transporter activity)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0051224"(negative regulation of protein transport)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:1901016"(regulation of potassium ion transmembrane transporter activity)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000569(HECT)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR024928|interpro:IPR035892|interpro:IPR035983|interpro:IPR036020|mint:O00308|rcsb pdb:4Y07|rcsb pdb:5TJ7|rcsb pdb:5TJ8|rcsb pdb:5TJQ|rcsb pdb:6J1Z|rcsb pdb:6RSS|reactome:R-HSA-8948751|reactome:R-HSA-9013406|reactome:R-HSA-9013409|reactome:R-HSA-9013420|reactome:R-HSA-9013507|entrezgene/locuslink:11060(identity)	sgd:S000003500|refseq:NP_011784.3|dip:DIP-1987N|ensemblfungi:YGR268C(gene)|ensemblfungi:YGR268C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|interpro:IPR038910|sgd:YGR268C(identity)	-	-	crc64:78029FD484168793	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Xj0Xssn75HP9sp/tHNe4n83eHPE9606	rogid:xliNG9XUWbYRd0Nbu+xzCgxNrAs559292	intact-crc:3E6748744021E6D7|rigid:YmFWIjYzfPfhf5yuAI2KMCmrd00	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:E9PFK9	uniprotkb:P40325	intact:EBI-11523104|ensembl:ENSP00000403429	intact:EBI-23614|uniprotkb:D6VV46|ensemblfungi:YGR268C	psi-mi:e9pfk9_human(display_long)|uniprotkb:RABGEF1(gene name)|psi-mi:RABGEF1(display_short)	psi-mi:hua1_yeast(display_long)|uniprotkb:HUA1(gene name)|psi-mi:HUA1(display_short)|uniprotkb:YGR268C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11530665|imex:IM-24995-872	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000154710(gene)|ensembl:ENST00000439720(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|interpro:IPR002653(Zinc finger, A20-type)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR037191|interpro:IPR041545|entrezgene/locuslink:27342(identity)	sgd:S000003500|refseq:NP_011784.3|dip:DIP-1987N|ensemblfungi:YGR268C(gene)|ensemblfungi:YGR268C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|interpro:IPR038910|sgd:YGR268C(identity)	-	-	crc64:78029FD484168793	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:JDHW8cuCB2z39j6a+LlkARnLfYo9606	rogid:xliNG9XUWbYRd0Nbu+xzCgxNrAs559292	intact-crc:C288C58465862AE9|rigid:HAvEPRZLIiZozCqVw7mjCvpShpU	false	sufficient binding region:14-504	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40325	uniprotkb:Q13137	intact:EBI-23614|uniprotkb:D6VV46|ensemblfungi:YGR268C	intact:EBI-739580|uniprotkb:B4DDC4|uniprotkb:E7ENK0|uniprotkb:Q53FQ5|uniprotkb:Q53HB5|uniprotkb:Q6IBN9|uniprotkb:Q9BTF7|uniprotkb:B2RBT0|ensembl:ENSP00000258947|uniprotkb:B4E0C0|uniprotkb:E7ETP5|uniprotkb:B4DDT4|uniprotkb:B4DP36|uniprotkb:E9PBE5	psi-mi:hua1_yeast(display_long)|uniprotkb:HUA1(gene name)|psi-mi:HUA1(display_short)|uniprotkb:YGR268C(locus name)	psi-mi:caco2_human(display_long)|uniprotkb:CALCOCO2(gene name)|psi-mi:CALCOCO2(display_short)|uniprotkb:NDP52(gene name synonym)|uniprotkb:Nuclear domain 10 protein NDP52(gene name synonym)|uniprotkb:Antigen nuclear dot 52 kDa protein(gene name synonym)|uniprotkb:Nuclear dot protein 52(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11530725|imex:IM-24995-878	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003500|refseq:NP_011784.3|dip:DIP-1987N|ensemblfungi:YGR268C(gene)|ensemblfungi:YGR268C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|interpro:IPR038910|sgd:YGR268C(identity)	refseq:NP_001248319.1|refseq:NP_001248320.1|refseq:NP_001248322.1|refseq:NP_005822.1|ensembl:ENSG00000136436(gene)|ensembl:ENST00000258947(transcript)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016032"(viral process)|go:"GO:0016605"(PML body)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0098792"(xenophagy)|go:"GO:1901098"(positive regulation of autophagosome maturation)|interpro:IPR041611|interpro:IPR041641|mint:Q13137|rcsb pdb:2MXP|rcsb pdb:3VVV|rcsb pdb:3VVW|rcsb pdb:4GXL|rcsb pdb:4HAN|rcsb pdb:4XKL|rcsb pdb:5AAQ|rcsb pdb:5Z7A|rcsb pdb:5Z7L|refseq:NP_001248324.1|dip:DIP-57534N|entrezgene/locuslink:10241(identity)	-	crc64:78029FD484168793	crc64:609B121DA1A9DCB8	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:xliNG9XUWbYRd0Nbu+xzCgxNrAs559292	rogid:N/GPJUGBK+Dh5Cg+csmafphuo9M9606	intact-crc:E72B38FDEF11DAC9|rigid:ZU1zP1fdskcG37I7zNqOy95qCLQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40325	uniprotkb:Q04323-2	intact:EBI-23614|uniprotkb:D6VV46|ensemblfungi:YGR268C	intact:EBI-11530712|ensembl:ENSP00000294119	psi-mi:hua1_yeast(display_long)|uniprotkb:HUA1(gene name)|psi-mi:HUA1(display_short)|uniprotkb:YGR268C(locus name)	psi-mi:q04323-2(display_long)|uniprotkb:UBXN1(gene name)|psi-mi:UBXN1(display_short)|uniprotkb:SAKS1(gene name synonym)|uniprotkb:SAPK substrate protein 1(gene name synonym)|uniprotkb:UBA/UBX 33.3 kDa protein(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11530716|imex:IM-24995-877	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003500|refseq:NP_011784.3|dip:DIP-1987N|ensemblfungi:YGR268C(gene)|ensemblfungi:YGR268C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|interpro:IPR038910|sgd:YGR268C(identity)	ensembl:ENSG00000162191(gene)|ensembl:ENST00000294119(transcript)|intact:EBI-1058647(isoform-parent)|uniprotkb:Q04323-2(isoform-parent)|entrezgene/locuslink:51035(identity)	-	crc64:78029FD484168793	isoform-comment:No experimental confirmation available.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:xliNG9XUWbYRd0Nbu+xzCgxNrAs559292	rogid:3DD93eyg5bSqmm3twiOfff+2Bps9606	intact-crc:92F28E219BD5A602|rigid:LciiCbDcklBbHVh0PdJE3y0ERzY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40325	uniprotkb:Q04323	intact:EBI-23614|uniprotkb:D6VV46|ensemblfungi:YGR268C	intact:EBI-1058647|ensembl:ENSP00000303991|uniprotkb:Q9BV93|uniprotkb:Q9BVV5|intact:EBI-1993649	psi-mi:hua1_yeast(display_long)|uniprotkb:HUA1(gene name)|psi-mi:HUA1(display_short)|uniprotkb:YGR268C(locus name)	psi-mi:ubxn1_human(display_long)|uniprotkb:UBXN1(gene name)|psi-mi:UBXN1(display_short)|uniprotkb:SAKS1(gene name synonym)|uniprotkb:SAPK substrate protein 1(gene name synonym)|uniprotkb:UBA/UBX 33.3 kDa protein(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11530703|imex:IM-24995-876	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003500|refseq:NP_011784.3|dip:DIP-1987N|ensemblfungi:YGR268C(gene)|ensemblfungi:YGR268C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|interpro:IPR038910|sgd:YGR268C(identity)	ensembl:ENSG00000162191(gene)|ensembl:ENST00000301935(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0030425"(dendrite)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0036435"(K48-linked polyubiquitin modification-dependent protein binding)|refseq:NP_001273006.1|refseq:NP_001273007.1|refseq:NP_056937.2|go:"GO:0043025"(neuronal cell body)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0051117"(ATPase binding)|go:"GO:0071796"(K6-linked polyubiquitin modification-dependent protein binding)|go:"GO:1903094"(negative regulation of protein K48-linked deubiquitination)|go:"GO:1904293"(negative regulation of ERAD pathway)|go:"GO:1904855"(proteasome regulatory particle binding)|go:"GO:2000157"(negative regulation of ubiquitin-specific protease activity)|interpro:IPR001012(UBX)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR029071|interpro:IPR041923|reactome:R-HSA-532668|reactome:R-HSA-5693565|go:"GO:0043130"(ubiquitin binding)|refseq:XP_005274090.1|refseq:XP_016873363.1|dip:DIP-29467N|entrezgene/locuslink:51035(identity)	-	crc64:78029FD484168793	crc64:E4E0C8BBAC93F2BB	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:xliNG9XUWbYRd0Nbu+xzCgxNrAs559292	rogid:KdHMRM9FSd6VT6MvJTxzdjARlRw9606	intact-crc:9695347333B3524B|rigid:Uta6w9dHHb/gnO/HqSVuBGJTaqE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O75886	uniprotkb:P40325	intact:EBI-373258|uniprotkb:Q7LDQ0|uniprotkb:Q9UF58|uniprotkb:A8K8A0|uniprotkb:D3DPA1|ensembl:ENSP00000263904	intact:EBI-23614|uniprotkb:D6VV46|ensemblfungi:YGR268C	psi-mi:stam2_human(display_long)|uniprotkb:STAM2(gene name)|psi-mi:STAM2(display_short)|uniprotkb:HBP(gene name synonym)|uniprotkb:Hrs-binding protein(gene name synonym)	psi-mi:hua1_yeast(display_long)|uniprotkb:HUA1(gene name)|psi-mi:HUA1(display_short)|uniprotkb:YGR268C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11530694|imex:IM-24995-875	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005834.4|ensembl:ENSG00000115145(gene)|ensembl:ENST00000263904(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0015031"(protein transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0031901"(early endosome membrane)|go:"GO:0033565"(ESCRT-0 complex)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR001452(Src homology-3)|interpro:IPR002014(VHS)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR035675|interpro:IPR036028|mint:O75886|rcsb pdb:1X2Q|rcsb pdb:1X5B|rcsb pdb:2L0T|rcsb pdb:5CRV|rcsb pdb:5IXF|reactome:R-HSA-182971|reactome:R-HSA-5689880|reactome:R-HSA-6807004|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8875360|reactome:R-HSA-9013420|reactome:R-HSA-917729|entrezgene/locuslink:10254(identity)	sgd:S000003500|refseq:NP_011784.3|dip:DIP-1987N|ensemblfungi:YGR268C(gene)|ensemblfungi:YGR268C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|interpro:IPR038910|sgd:YGR268C(identity)	-	-	crc64:78029FD484168793	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:e5brcAWS5So29SdnZV3cAm/dZAk9606	rogid:xliNG9XUWbYRd0Nbu+xzCgxNrAs559292	intact-crc:54B4FC9801E6C9E1|rigid:0Ll8W5USnqPLfOJFREug13vfCME	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96C32	uniprotkb:P40325	intact:EBI-745483|ensembl:ENSP00000443053	intact:EBI-23614|uniprotkb:D6VV46|ensemblfungi:YGR268C	psi-mi:q96c32_human(display_long)|uniprotkb:UBC(gene name)|psi-mi:UBC(display_short)	psi-mi:hua1_yeast(display_long)|uniprotkb:HUA1(gene name)|psi-mi:HUA1(display_short)|uniprotkb:YGR268C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11530754|imex:IM-24995-881	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000150991(gene)|ensembl:ENST00000538617(transcript)|interpro:IPR000626(Ubiquitin)|interpro:IPR019954|interpro:IPR019956|interpro:IPR029071|entrezgene/locuslink:7316(identity)	sgd:S000003500|refseq:NP_011784.3|dip:DIP-1987N|ensemblfungi:YGR268C(gene)|ensemblfungi:YGR268C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|interpro:IPR038910|sgd:YGR268C(identity)	-	-	crc64:78029FD484168793	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:IkHD1AAO/mSSvaZqrZi5tXVfPOw9606	rogid:xliNG9XUWbYRd0Nbu+xzCgxNrAs559292	intact-crc:B42DDB3683627A33|rigid:yFAItV8WCJx6w3KzRXcFvymZeww	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40325	uniprotkb:Q15025	intact:EBI-23614|uniprotkb:D6VV46|ensemblfungi:YGR268C	intact:EBI-357849|uniprotkb:A4F1W8|uniprotkb:O76008|uniprotkb:Q96EL9|uniprotkb:Q99833|uniprotkb:Q9H1J3|uniprotkb:B7Z699|uniprotkb:Q6N077|ensembl:ENSP00000317891|ensembl:ENSP00000428187|ensembl:ENSP00000430760|uniprotkb:A4F1W9|uniprotkb:A4F1X2|uniprotkb:A4F1X4|uniprotkb:A4F1X5|uniprotkb:A4F1X6|uniprotkb:A4F1X7|uniprotkb:A4F1X9|uniprotkb:E7EPY1|uniprotkb:E7ET96|uniprotkb:Q05KP3|uniprotkb:Q05KP4	psi-mi:hua1_yeast(display_long)|uniprotkb:HUA1(gene name)|psi-mi:HUA1(display_short)|uniprotkb:YGR268C(locus name)	psi-mi:tnip1_human(display_long)|uniprotkb:TNIP1(gene name)|psi-mi:TNIP1(display_short)|uniprotkb:KIAA0113(gene name synonym)|uniprotkb:NAF1(gene name synonym)|uniprotkb:Nef-associated factor 1(gene name synonym)|uniprotkb:HIV-1 Nef-interacting protein(gene name synonym)|uniprotkb:Virion-associated nuclear shuttling protein(gene name synonym)|uniprotkb:Nip40-1(gene name synonym)|uniprotkb:A20-binding inhibitor of NF-kappa-B activation 1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11530744|imex:IM-24995-880	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003500|refseq:NP_011784.3|dip:DIP-1987N|ensemblfungi:YGR268C(gene)|ensemblfungi:YGR268C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|interpro:IPR038910|sgd:YGR268C(identity)	refseq:NP_006049.3|refseq:NP_001239319.1|refseq:NP_001239320.1|refseq:NP_001239321.1|refseq:NP_001239322.1|refseq:NP_001245383.1|dip:DIP-27577N|refseq:NP_001239315.1|ensembl:ENSG00000145901(gene)|ensembl:ENST00000315050(transcript)|ensembl:ENST00000521591(transcript)|ensembl:ENST00000522226(transcript)|go:"GO:0002755"(MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0006952"(defense response)|go:"GO:0006954"(inflammatory response)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0009101"(glycoprotein biosynthetic process)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0085032"(modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade)|go:"GO:1903003"(positive regulation of protein deubiquitination)|interpro:IPR033372|mint:Q15025|reactome:R-HSA-5689896|go:"GO:0051019"(mitogen-activated protein kinase binding)|refseq:NP_001239314.1|refseq:NP_001245384.1|refseq:NP_001245385.1|refseq:XP_006714814.1|refseq:XP_006714815.1|entrezgene/locuslink:10318(identity)	-	crc64:78029FD484168793	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:xliNG9XUWbYRd0Nbu+xzCgxNrAs559292	rogid:16Vjb5CuGTAbW2M22qbCxgXtV1o9606	intact-crc:B60CDA30DC2E63C9|rigid:yPFZ0WNJj6iZqkuwZFycMhRekpE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40325	uniprotkb:Q13490	intact:EBI-23614|uniprotkb:D6VV46|ensemblfungi:YGR268C	intact:EBI-514538|uniprotkb:Q16516|uniprotkb:Q4TTG0|uniprotkb:B4E026|ensembl:ENSP00000227758|ensembl:ENSP00000477613	psi-mi:hua1_yeast(display_long)|uniprotkb:HUA1(gene name)|psi-mi:HUA1(display_short)|uniprotkb:YGR268C(locus name)	psi-mi:birc2_human(display_long)|uniprotkb:Inhibitor of apoptosis protein 2(gene name synonym)|uniprotkb:TNFR2-TRAF-signaling complex protein 2(gene name synonym)|uniprotkb:IAP homolog B(gene name synonym)|uniprotkb:RING finger protein 48(gene name synonym)|uniprotkb:BIRC2(gene name)|psi-mi:BIRC2(display_short)|uniprotkb:API1(gene name synonym)|uniprotkb:MIHB(gene name synonym)|uniprotkb:RNF48(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase BIRC2(gene name synonym)|uniprotkb:Cellular inhibitor of apoptosis 1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11530735|imex:IM-24995-879	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003500|refseq:NP_011784.3|dip:DIP-1987N|ensemblfungi:YGR268C(gene)|ensemblfungi:YGR268C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|interpro:IPR038910|sgd:YGR268C(identity)	refseq:NP_001157.1|refseq:NP_001243095.1|refseq:NP_001243092.1|dip:DIP-33485N|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0045471"(response to ethanol)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051087"(chaperone binding)|go:"GO:0051591"(response to cAMP)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060544"(regulation of necroptotic process)|go:"GO:0060546"(negative regulation of necroptotic process)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070266"(necroptotic process)|go:"GO:0070424"(regulation of nucleotide-binding oligomerization domain containing signaling pathway)|go:"GO:0098770"(FBXO family protein binding)|go:"GO:1901222"(regulation of NIK/NF-kappaB signaling)|go:"GO:1902443"(negative regulation of ripoptosome assembly involved in necroptotic process)|go:"GO:1902523"(positive regulation of protein K63-linked ubiquitination)|go:"GO:1902524"(positive regulation of protein K48-linked ubiquitination)|go:"GO:1902527"(positive regulation of protein monoubiquitination)|go:"GO:2000116"(regulation of cysteine-type endopeptidase activity)|go:"GO:2000377"(regulation of reactive oxygen species metabolic process)|interpro:IPR001315(Caspase Recruitment)|interpro:IPR001370(Proteinase inhibitor I32, inhibitor of apoptosis)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011029(DEATH-like)|interpro:IPR041933|mint:Q13490|rcsb pdb:1QBH|rcsb pdb:2L9M|rcsb pdb:3D9T|rcsb pdb:3D9U|rcsb pdb:3M1D|rcsb pdb:3MUP|rcsb pdb:3OZ1|rcsb pdb:3T6P|rcsb pdb:3UW4|rcsb pdb:4EB9|rcsb pdb:4HY4|rcsb pdb:4HY5|rcsb pdb:4KMN|rcsb pdb:4LGE|rcsb pdb:4LGU|rcsb pdb:4MTI|rcsb pdb:4MU7|rcsb pdb:5M6N|rcsb pdb:6EXW|rcsb pdb:6HPR|rcsb pdb:6W74|rcsb pdb:6W7O|rcsb pdb:6W8I|reactome:R-HSA-111465|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-5213460|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5668541|reactome:R-HSA-5675482|reactome:R-HSA-5676594|reactome:R-HSA-5689880|reactome:R-HSA-937041|ensembl:ENSG00000110330(gene)|ensembl:ENST00000227758(transcript)|ensembl:ENST00000613397(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001741"(XY body)|go:"GO:0001890"(placenta development)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0016740"(transferase activity)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034121"(regulation of toll-like receptor signaling pathway)|go:"GO:0035631"(CD40 receptor complex)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0039535"(regulation of RIG-I signaling pathway)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|entrezgene/locuslink:329(identity)	-	crc64:78029FD484168793	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:xliNG9XUWbYRd0Nbu+xzCgxNrAs559292	rogid:FOikzyDyDtlv2l69i/WNDNq674A9606	intact-crc:979747B68F89CCA3|rigid:Pl0sRkozh4Fe0A0tmTVh9BsVWgY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40325	uniprotkb:Q9UMX0	intact:EBI-23614|uniprotkb:D6VV46|ensemblfungi:YGR268C	intact:EBI-741480|uniprotkb:Q8IXS9|uniprotkb:Q8N2Q3|uniprotkb:Q9H0T8|uniprotkb:Q9H3R4|uniprotkb:Q9HAZ5|intact:EBI-28967608|ensembl:ENSP00000365576|uniprotkb:Q5T6J5|uniprotkb:Q5T6J9|uniprotkb:A0A024R284	psi-mi:hua1_yeast(display_long)|uniprotkb:HUA1(gene name)|psi-mi:HUA1(display_short)|uniprotkb:YGR268C(locus name)	psi-mi:ubql1_human(display_long)|uniprotkb:Protein linking IAP with cytoskeleton 1(gene name synonym)|uniprotkb:UBQLN1(gene name)|psi-mi:UBQLN1(display_short)|uniprotkb:DA41(gene name synonym)|uniprotkb:PLIC1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11530790|imex:IM-24995-885	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003500|refseq:NP_011784.3|dip:DIP-1987N|ensemblfungi:YGR268C(gene)|ensemblfungi:YGR268C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|interpro:IPR038910|sgd:YGR268C(identity)	ensembl:ENST00000257468|ensembl:ENSP00000257468|ensembl:ENSP00000365576|ensembl:ENSG00000135018(gene)|ensembl:ENST00000376395(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000502"(proteasome complex)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016235"(aggresome)|go:"GO:0016236"(macroautophagy)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0019900"(kinase binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035973"(aggrephagy)|go:"GO:0042802"(identical protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0097352"(autophagosome maturation)|go:"GO:1901340"(negative regulation of store-operated calcium channel activity)|go:"GO:1902175"(regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)|interpro:IPR000626(Ubiquitin)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR028430|interpro:IPR029071|mint:Q9UMX0|rcsb pdb:2JY5|rcsb pdb:2JY6|rcsb pdb:2KLC|reactome:R-HSA-8856825|refseq:NP_038466.2|refseq:NP_444295.1|dip:DIP-41629N|entrezgene/locuslink:29979(identity)	-	crc64:78029FD484168793	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:xliNG9XUWbYRd0Nbu+xzCgxNrAs559292	rogid:nCFfZbGCTvRYaXhQ4R99XblslvM9606	intact-crc:7382AEF110749D37|rigid:MJOj4t/4plp19fbfmUPOCxunltg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9NPJ6	uniprotkb:P40325	intact:EBI-394607|uniprotkb:Q9BS95|uniprotkb:Q9NYR5|uniprotkb:Q53GB4|uniprotkb:Q53H68|uniprotkb:Q5T912|uniprotkb:Q6FHC4|uniprotkb:Q6IA79|uniprotkb:B4DX67|ensembl:ENSP00000258648	intact:EBI-23614|uniprotkb:D6VV46|ensemblfungi:YGR268C	psi-mi:med4_human(display_long)|uniprotkb:HSPC126(orf name)|uniprotkb:DRIP36(gene name synonym)|uniprotkb:MED4(gene name)|psi-mi:MED4(display_short)|uniprotkb:ARC36(gene name synonym)|uniprotkb:Mediator complex subunit 4(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex 36 kDa component(gene name synonym)|uniprotkb:Activator-recruited cofactor 36 kDa component(gene name synonym)|uniprotkb:TRAP/SMCC/PC2 subunit p36 subunit(gene name synonym)|uniprotkb:VDRIP(gene name synonym)	psi-mi:hua1_yeast(display_long)|uniprotkb:HUA1(gene name)|psi-mi:HUA1(display_short)|uniprotkb:YGR268C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11530781|imex:IM-24995-884	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001257558.1|refseq:NP_054885.1|ensembl:ENSG00000136146(gene)|ensembl:ENST00000258648(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0070847"(core mediator complex)|interpro:IPR019258|mint:Q9NPJ6|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|entrezgene/locuslink:29079(identity)	sgd:S000003500|refseq:NP_011784.3|dip:DIP-1987N|ensemblfungi:YGR268C(gene)|ensemblfungi:YGR268C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|interpro:IPR038910|sgd:YGR268C(identity)	-	-	crc64:78029FD484168793	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Bept2Oec50gruA9e4pf+eEUiANM9606	rogid:xliNG9XUWbYRd0Nbu+xzCgxNrAs559292	intact-crc:61858BF294B08A62|rigid:YjjL0fdYfJwMYhA7NMox2pVSZCI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96CV9-2	uniprotkb:P40325	intact:EBI-9091423|ensembl:ENSP00000368027|ensembl:ENSP00000368040	intact:EBI-23614|uniprotkb:D6VV46|ensemblfungi:YGR268C	psi-mi:q96cv9-2(display_long)|uniprotkb:E3-14.7K-interacting protein(gene name synonym)|uniprotkb:FIP-2(gene name synonym)|uniprotkb:FIP2(gene name synonym)|uniprotkb:GLC1E(gene name synonym)|uniprotkb:HIP7(gene name synonym)|uniprotkb:HYPL(gene name synonym)|uniprotkb:Huntingtin yeast partner L(gene name synonym)|uniprotkb:Huntingtin-interacting protein 7(gene name synonym)|uniprotkb:Huntingtin-interacting protein L(gene name synonym)|uniprotkb:NEMO-related protein(gene name synonym)|uniprotkb:NRP(gene name synonym)|uniprotkb:Optic neuropathy-inducing protein(gene name synonym)|uniprotkb:Transcription factor IIIA-interacting protein(gene name synonym)|uniprotkb:OPTN(gene name)|psi-mi:OPTN(display_short)	psi-mi:hua1_yeast(display_long)|uniprotkb:HUA1(gene name)|psi-mi:HUA1(display_short)|uniprotkb:YGR268C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11530772|imex:IM-24995-883	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-748974(isoform-parent)|ensembl:ENST00000378752(transcript)|ensembl:ENST00000378764(transcript)|ensembl:ENSG00000123240(gene)|uniprotkb:Q96CV9-2(isoform-parent)|entrezgene/locuslink:10133(identity)	sgd:S000003500|refseq:NP_011784.3|dip:DIP-1987N|ensemblfungi:YGR268C(gene)|ensemblfungi:YGR268C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|interpro:IPR038910|sgd:YGR268C(identity)	-	isoform-comment:No experimental confirmation available.	crc64:78029FD484168793	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2018/04/06	rogid:ygzEQkiDJwDAMUuFQuOWsSIqwAk9606	rogid:xliNG9XUWbYRd0Nbu+xzCgxNrAs559292	intact-crc:3064B085916CD60E|rigid:uOCMr9eJT/Mm90dBbTyVfrbsS5o	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40325	uniprotkb:Q96CV9	intact:EBI-23614|uniprotkb:D6VV46|ensemblfungi:YGR268C	intact:EBI-748974|uniprotkb:Q5T672|uniprotkb:Q5T673|uniprotkb:Q5T674|uniprotkb:Q5T675|uniprotkb:Q7LDL9|uniprotkb:Q8N562|uniprotkb:Q9UET9|uniprotkb:Q9UEV4|uniprotkb:Q9Y218|uniprotkb:B3KP00|uniprotkb:D3DRS4|uniprotkb:D3DRS8|ensembl:ENSP00000263036|ensembl:ENSP00000368021|ensembl:ENSP00000368022|ensembl:ENSP00000368032	psi-mi:hua1_yeast(display_long)|uniprotkb:HUA1(gene name)|psi-mi:HUA1(display_short)|uniprotkb:YGR268C(locus name)	psi-mi:optn_human(display_long)|uniprotkb:HYPL(gene name synonym)|uniprotkb:Optic neuropathy-inducing protein(gene name synonym)|uniprotkb:E3-14.7K-interacting protein(gene name synonym)|uniprotkb:FIP-2(gene name synonym)|uniprotkb:Huntingtin-interacting protein L(gene name synonym)|uniprotkb:Huntingtin yeast partner L(gene name synonym)|uniprotkb:NEMO-related protein(gene name synonym)|uniprotkb:Transcription factor IIIA-interacting protein(gene name synonym)|uniprotkb:OPTN(gene name)|psi-mi:OPTN(display_short)|uniprotkb:FIP2(gene name synonym)|uniprotkb:GLC1E(gene name synonym)|uniprotkb:NRP(gene name synonym)|uniprotkb:HIP7(gene name synonym)|uniprotkb:Huntingtin-interacting protein 7(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11530763|imex:IM-24995-882	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003500|refseq:NP_011784.3|dip:DIP-1987N|ensemblfungi:YGR268C(gene)|ensemblfungi:YGR268C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|interpro:IPR038910|sgd:YGR268C(identity)	refseq:NP_001008212.1|refseq:NP_001008213.1|refseq:NP_001008214.1|refseq:NP_068815.2|ensembl:ENSG00000123240(gene)|ensembl:ENST00000263036(transcript)|ensembl:ENST00000378747(transcript)|ensembl:ENST00000378748(transcript)|ensembl:ENST00000378757(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001920"(negative regulation of receptor recycling)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0007030"(Golgi organization)|go:"GO:0007165"(signal transduction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008219"(cell death)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0061734"(parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:1904417"(positive regulation of xenophagy)|interpro:IPR021063|interpro:IPR032419|interpro:IPR032939|interpro:IPR034735|mint:Q96CV9|rcsb pdb:2LO4|rcsb pdb:2LUE|rcsb pdb:3VTV|rcsb pdb:3VTW|rcsb pdb:5AAZ|rcsb pdb:5B83|rcsb pdb:5EOA|rcsb pdb:5EOF|rcsb pdb:7CZM|reactome:R-HSA-2565942|reactome:R-HSA-8854214|dip:DIP-42001N|entrezgene/locuslink:10133(identity)	-	crc64:78029FD484168793	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2018/04/06	rogid:xliNG9XUWbYRd0Nbu+xzCgxNrAs559292	rogid:jcCTXDx1bJq3K5mgNUD73jeWeBU9606	intact-crc:487396FE185DFB90|rigid:XRF29S3IqlMdBF01fxwAe3LRwug	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P37198	uniprotkb:P40368	intact:EBI-347978|intact:EBI-28983799|ensembl:ENSP00000305503|ensembl:ENSP00000407331|ensembl:ENSP00000471191|ensembl:ENSP00000473192|uniprotkb:Q6GTM2|uniprotkb:Q503A4|uniprotkb:Q96C43|uniprotkb:Q9NSL1|uniprotkb:B3KWU5	intact:EBI-12331|ensemblfungi:YJL061W|uniprotkb:D6VWC1	psi-mi:nup62_human(display_long)|uniprotkb:NUP62(gene name)|psi-mi:NUP62(display_short)|uniprotkb:62 kDa nucleoporin(gene name synonym)|uniprotkb:Nucleoporin Nup62(gene name synonym)	psi-mi:nup82_yeast(display_long)|uniprotkb:NUP82(gene name)|psi-mi:NUP82(display_short)|uniprotkb:YJL061W(locus name)|uniprotkb:J1135(orf name)|uniprotkb:HRB187(orf name)|uniprotkb:Nuclear pore protein NUP82(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11530824|imex:IM-24995-888	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_714941.1|ensembl:ENSG00000213024(gene)|ensembl:ENST00000352066(transcript)|ensembl:ENST00000422090(transcript)|ensembl:ENST00000596217(transcript)|ensembl:ENST00000597029(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005642"(annulate lamellae)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007100"(mitotic centrosome separation)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007569"(cell aging)|go:"GO:0008219"(cell death)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0003682"(chromatin binding)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0019894"(kinesin binding)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042306"(regulation of protein import into nucleus)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043069"(negative regulation of programmed cell death)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045742"(positive regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046578"(regulation of Ras protein signal transduction)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0046601"(positive regulation of centriole replication)|go:"GO:0051028"(mRNA transport)|go:"GO:0051425"(PTB domain binding)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0072686"(mitotic spindle)|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|go:"GO:0090543"(Flemming body)|go:"GO:0098534"(centriole assembly)|go:"GO:1903438"(positive regulation of mitotic cytokinetic process)|go:"GO:1904781"(positive regulation of protein localization to centrosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR007758(Nucleoporin, Nsp1-like, C-terminal)|interpro:IPR026010|interpro:IPR033072|mint:P37198|rcsb pdb:2H4D|rcsb pdb:5IJN|rcsb pdb:5IJO|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|refseq:NP_714940.1|refseq:NP_001180286.1|refseq:NP_036478.2|refseq:NP_057637.2|ensembl:ENSP00000305503|ensembl:ENSP00000407331|ensembl:ENSP00000471191|ensembl:ENSP00000473192|dip:DIP-29749N|entrezgene/locuslink:23636(identity)	refseq:NP_012474.1|sgd:S000003597|ensemblfungi:YJL061W(gene)|ensemblfungi:YJL061W_mRNA(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0005634"(nucleus)|interpro:IPR037700|rcsb pdb:3PBP|rcsb pdb:3TKN|go:"GO:0005643"(nuclear pore)|go:"GO:0005829"(cytosol)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0044612"(nuclear pore linkers)|go:"GO:0044614"(nuclear pore cytoplasmic filaments)|mint:P40368|dip:DIP-913N|sgd:YJL061W(identity)	-	-	crc64:C379B5E111E26B50	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:v7mvKvTtVEnLMwcpUZIcdAzge009606	rogid:g1+jqOMmde8phrNI9H7nFlXwjH0559292	intact-crc:C5B50FCB36C25887|rigid:RwOsFdGv+DFarKE9DT5kv5U33iw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:A2A369	uniprotkb:P40354	intact:EBI-11530808|ensembl:ENSP00000371766	intact:EBI-12280|ensemblfungi:YJR062C|uniprotkb:D6VWN3	psi-mi:a2a369_human(display_long)|uniprotkb:DOCK8(gene name)|psi-mi:DOCK8(display_short)	psi-mi:nta1_yeast(display_long)|uniprotkb:J1742(orf name)|uniprotkb:YJR062C(locus name)|uniprotkb:NTA1(gene name)|psi-mi:NTA1(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11530813|imex:IM-24995-887	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000107099(gene)|ensembl:ENST00000382329(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0007264"(small GTPase mediated signal transduction)|interpro:IPR010703(Dedicator of cytokinesis)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026791|interpro:IPR027007|interpro:IPR027357|interpro:IPR035892|interpro:IPR043161|interpro:IPR043162|entrezgene/locuslink:81704(identity)	ensemblfungi:YJR062C(gene)|ensemblfungi:YJR062C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0008418"(protein-N-terminal asparagine amidohydrolase activity)|go:"GO:0030163"(protein catabolic process)|go:"GO:0031365"(N-terminal protein amino acid modification)|go:"GO:0070773"(protein-N-terminal glutamine amidohydrolase activity)|interpro:IPR003010(Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase)|interpro:IPR036526|interpro:IPR039703|refseq:NP_012596.3|sgd:S000003823|dip:DIP-6478N|sgd:YJR062C(identity)	-	-	crc64:E6259FBBFB25A889	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Sa5ulmmVxrpxZ+GAhN64RAHXYdk9606	rogid:WuneoUOKjrppTwFurxcO41hR/W0559292	intact-crc:363ADB12E65748E0|rigid:hW09oO4w8ZshylXet9c+t1cQ05Q	false	sufficient binding region:1054-1566	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8NHQ1	uniprotkb:P40348	intact:EBI-739624|ensembl:ENSP00000264982|ensembl:ENSP00000419231|uniprotkb:Q96B31|uniprotkb:Q9H2C3|uniprotkb:Q9H2Z1|uniprotkb:Q9H940|uniprotkb:D3DNE9|uniprotkb:B7Z5I8|uniprotkb:B7Z7E8|uniprotkb:F5GZX8	intact:EBI-14992|uniprotkb:E9P8U1|uniprotkb:D6VWN9|ensemblfungi:YJR068W	psi-mi:cep70_human(display_long)|uniprotkb:CEP70(gene name)|psi-mi:CEP70(display_short)|uniprotkb:BITE(gene name synonym)|uniprotkb:p10-binding protein(gene name synonym)	psi-mi:rfc2_yeast(display_long)|uniprotkb:RFC2(gene name)|psi-mi:RFC2(display_short)|uniprotkb:YJR068W(locus name)|uniprotkb:J1808(orf name)|uniprotkb:Activator 1 41 kDa subunit(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11530799|imex:IM-24995-886	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114107(gene)|ensembl:ENST00000264982(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|interpro:IPR019734|interpro:IPR037692|mint:Q8NHQ1|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|ensembl:ENST00000484888(transcript)|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_077817.2|refseq:XP_016862764.1|refseq:NP_001275893.1|refseq:NP_001275894.1|refseq:NP_001275895.1|refseq:NP_001275896.1|refseq:NP_001307527.1|refseq:NP_001307529.1|entrezgene/locuslink:80321(identity)	sgd:S000003829|refseq:NP_012602.3|ensemblfungi:YJR068W(gene)|ensemblfungi:YJR068W_mRNA(transcript)|go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005663"(DNA replication factor C complex)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006272"(leading strand elongation)|go:"GO:0006281"(DNA repair)|go:"GO:0006298"(mismatch repair)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0031389"(Rad17 RFC-like complex)|go:"GO:0031390"(Ctf18 RFC-like complex)|go:"GO:0031391"(Elg1 RFC-like complex)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR013748(Replication factor C)|interpro:IPR027417|rcsb pdb:1SXJ|reactome:R-SCE-110312|reactome:R-SCE-110320|reactome:R-SCE-176187|reactome:R-SCE-5655862|reactome:R-SCE-5656121|reactome:R-SCE-5656169|reactome:R-SCE-5696397|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-69091|dip:DIP-2528N|mint:P40348|sgd:YJR068W(identity)	-	-	crc64:59B2C4223B0D13BF	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:S4yveQWcvdVtAUX65gqrJ5Dv0Mc9606	rogid:Z0Rwf5Gg3mAcfGIC8toCXrjnD2g559292	intact-crc:9702B3EAB7194F82|rigid:ZQXGmLKGNXI8B5Paj1yQo5BBS6A	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40368	uniprotkb:Q9Y3C0	intact:EBI-12331|ensemblfungi:YJL061W|uniprotkb:D6VWC1	intact:EBI-712969|ensembl:ENSP00000240079|uniprotkb:Q53FF0|uniprotkb:Q6IAI4|uniprotkb:Q96QK0|uniprotkb:B2RC74	psi-mi:nup82_yeast(display_long)|uniprotkb:NUP82(gene name)|psi-mi:NUP82(display_short)|uniprotkb:YJL061W(locus name)|uniprotkb:J1135(orf name)|uniprotkb:HRB187(orf name)|uniprotkb:Nuclear pore protein NUP82(gene name synonym)	psi-mi:wasc3_human(display_long)|uniprotkb:WASHC3(gene name)|psi-mi:WASHC3(display_short)|uniprotkb:Coiled-coil domain-containing protein 53(gene name synonym)|uniprotkb:AD-016(orf name)|uniprotkb:CCDC53(orf name)|uniprotkb:CGI-116(orf name)|uniprotkb:x0009(orf name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11530851|imex:IM-24995-891	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012474.1|sgd:S000003597|ensemblfungi:YJL061W(gene)|ensemblfungi:YJL061W_mRNA(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0005634"(nucleus)|interpro:IPR037700|rcsb pdb:3PBP|rcsb pdb:3TKN|go:"GO:0005643"(nuclear pore)|go:"GO:0005829"(cytosol)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0044612"(nuclear pore linkers)|go:"GO:0044614"(nuclear pore cytoplasmic filaments)|mint:P40368|dip:DIP-913N|sgd:YJL061W(identity)	ensembl:ENSG00000120860(gene)|ensembl:ENST00000240079(transcript)|go:"GO:0005769"(early endosome)|go:"GO:0006887"(exocytosis)|go:"GO:0015031"(protein transport)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0071203"(WASH complex)|interpro:IPR019309|mint:Q9Y3C0|refseq:NP_057137.1|entrezgene/locuslink:51019(identity)	-	crc64:C379B5E111E26B50	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:g1+jqOMmde8phrNI9H7nFlXwjH0559292	rogid:jonEQJt0wEcrS2YEiKcmmIiZjCA9606	intact-crc:A63A4CF705CB64AA|rigid:+K6/4kcgYqa47kJX3VAfnTyqRmY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40368	uniprotkb:Q9HCM9-2	intact:EBI-12331|ensemblfungi:YJL061W|uniprotkb:D6VWC1	intact:EBI-11523450|ensembl:ENSP00000365847|ensembl:ENSP00000373095|ensembl:ENSP00000373097|ensembl:ENSP00000379797|ensembl:ENSP00000379800|ensembl:ENSP00000383486|ensembl:ENSP00000387445|ensembl:ENSP00000389198|ensembl:ENSP00000389852|ensembl:ENSP00000392130|ensembl:ENSP00000394353|ensembl:ENSP00000396986|ensembl:ENSP00000398956|ensembl:ENSP00000401071|ensembl:ENSP00000401184|ensembl:ENSP00000404340|ensembl:ENSP00000404904|ensembl:ENSP00000411582|ensembl:ENSP00000412743|ensembl:ENSP00000414525|ensembl:ENSP00000415259	psi-mi:nup82_yeast(display_long)|uniprotkb:NUP82(gene name)|psi-mi:NUP82(display_short)|uniprotkb:YJL061W(locus name)|uniprotkb:J1135(orf name)|uniprotkb:HRB187(orf name)|uniprotkb:Nuclear pore protein NUP82(gene name synonym)	psi-mi:q9hcm9-2(display_long)|uniprotkb:TRIM39(gene name)|psi-mi:TRIM39(display_short)|uniprotkb:RING finger protein 23(gene name synonym)|uniprotkb:RNF23(gene name synonym)|uniprotkb:TFP(gene name synonym)|uniprotkb:Testis-abundant finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 39(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM39(gene name synonym)|uniprotkb:TIM39beta(isoform synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11530842|imex:IM-24995-890	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012474.1|sgd:S000003597|ensemblfungi:YJL061W(gene)|ensemblfungi:YJL061W_mRNA(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0005634"(nucleus)|interpro:IPR037700|rcsb pdb:3PBP|rcsb pdb:3TKN|go:"GO:0005643"(nuclear pore)|go:"GO:0005829"(cytosol)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0044612"(nuclear pore linkers)|go:"GO:0044614"(nuclear pore cytoplasmic filaments)|mint:P40368|dip:DIP-913N|sgd:YJL061W(identity)	intact:EBI-739510(isoform-parent)|ensembl:ENSG00000204599(gene)|ensembl:ENSG00000206495(gene)|ensembl:ENSG00000224994(gene)|ensembl:ENSG00000226437(gene)|ensembl:ENSG00000229929(gene)|ensembl:ENSG00000230308(gene)|ensembl:ENSG00000232839(gene)|ensembl:ENST00000376659(transcript)|ensembl:ENST00000383601(transcript)|ensembl:ENST00000383603(transcript)|ensembl:ENST00000396548(transcript)|ensembl:ENST00000396551(transcript)|ensembl:ENST00000400644(transcript)|ensembl:ENST00000414015(transcript)|ensembl:ENST00000419790(transcript)|ensembl:ENST00000430502(transcript)|ensembl:ENST00000431272(transcript)|ensembl:ENST00000433900(transcript)|ensembl:ENST00000438076(transcript)|ensembl:ENST00000438859(transcript)|ensembl:ENST00000440117(transcript)|ensembl:ENST00000443109(transcript)|ensembl:ENST00000446397(transcript)|ensembl:ENST00000449318(transcript)|ensembl:ENST00000450778(transcript)|ensembl:ENST00000451132(transcript)|ensembl:ENST00000452705(transcript)|ensembl:ENST00000458607(transcript)|uniprotkb:Q9HCM9-2(isoform-parent)|entrezgene/locuslink:56658(identity)	-	crc64:C379B5E111E26B50	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:g1+jqOMmde8phrNI9H7nFlXwjH0559292	rogid:UfSn2+IVRxtGomVeDGdZpL7mz5I9606	intact-crc:69331182142FF5A4|rigid:puDWn9l6XgDWaTpECixgtQCXIGI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40368	uniprotkb:Q9BQD3	intact:EBI-12331|ensemblfungi:YJL061W|uniprotkb:D6VWC1	intact:EBI-739657|uniprotkb:O76098|ensembl:ENSP00000472678|ensembl:ENSP00000472836|ensembl:ENSP00000222307|ensembl:ENSP00000438903|ensembl:ENSP00000443549|ensembl:ENSP00000468990|ensembl:ENSP00000471554	psi-mi:nup82_yeast(display_long)|uniprotkb:NUP82(gene name)|psi-mi:NUP82(display_short)|uniprotkb:YJL061W(locus name)|uniprotkb:J1135(orf name)|uniprotkb:HRB187(orf name)|uniprotkb:Nuclear pore protein NUP82(gene name synonym)	psi-mi:kxdl1_human(display_long)|uniprotkb:KXD1(gene name)|psi-mi:KXD1(display_short)|uniprotkb:C19orf50(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11530833|imex:IM-24995-889	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012474.1|sgd:S000003597|ensemblfungi:YJL061W(gene)|ensemblfungi:YJL061W_mRNA(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0005634"(nucleus)|interpro:IPR037700|rcsb pdb:3PBP|rcsb pdb:3TKN|go:"GO:0005643"(nuclear pore)|go:"GO:0005829"(cytosol)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0044612"(nuclear pore linkers)|go:"GO:0044614"(nuclear pore cytoplasmic filaments)|mint:P40368|dip:DIP-913N|sgd:YJL061W(identity)	refseq:NP_001165419.1|refseq:NP_001165420.1|refseq:NP_076974.2|ensembl:ENST00000222307(transcript)|ensembl:ENST00000539106(transcript)|ensembl:ENST00000540691(transcript)|ensembl:ENST00000595073(transcript)|ensembl:ENST00000599319(transcript)|ensembl:ENST00000600654(transcript)|ensembl:ENST00000602094(transcript)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0032418"(lysosome localization)|go:"GO:0099078"(BORC complex)|interpro:IPR019371|interpro:IPR039843|ensembl:ENSG00000105700(gene)|refseq:XP_016882770.1|refseq:XP_011526574.1|refseq:XP_011526575.1|refseq:XP_006722946.1|entrezgene/locuslink:79036(identity)	-	crc64:C379B5E111E26B50	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:g1+jqOMmde8phrNI9H7nFlXwjH0559292	rogid:5BoR6AN0Ywb1eI04Rw4chmlWVI09606	intact-crc:9E086F1551A81D4F|rigid:z+3r6dsLXpSeZpn1SwXxTO88OOM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:G5E962	uniprotkb:P40454	intact:EBI-11525615|ensembl:ENSP00000328177	intact:EBI-25278|uniprotkb:D6VVD4|ensemblfungi:YIL153W	psi-mi:g5e962_human(display_long)|uniprotkb:hCG_1644200(orf name)|uniprotkb:MAGEA11(gene name)|psi-mi:MAGEA11(display_short)	psi-mi:ptpa1_yeast(display_long)|uniprotkb:YIL153W(locus name)|uniprotkb:RRD1(gene name)|psi-mi:RRD1(display_short)|uniprotkb:NCS1(gene name synonym)|uniprotkb:YPA1(gene name synonym)|uniprotkb:Peptidyl-prolyl cis-trans isomerase PTPA-1(gene name synonym)|uniprotkb:Phosphotyrosyl phosphatase activator 1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11530882|imex:IM-24995-894	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001011544.1|ensembl:ENSG00000185247(gene)|ensembl:ENST00000333104(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016604"(nuclear body)|interpro:IPR002190(MAGE protein)|interpro:IPR021072|interpro:IPR030099|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|entrezgene/locuslink:4110(identity)	refseq:NP_012113.1|sgd:S000001415|mint:P40454|dip:DIP-5663N|ensemblfungi:YIL153W(gene)|ensemblfungi:YIL153W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006914"(autophagy)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008160"(protein tyrosine phosphatase activator activity)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0043618"(regulation of transcription from RNA polymerase II promoter in response to stress)|interpro:IPR004327(Phosphotyrosyl phosphatase activator, PTPA)|interpro:IPR037218|interpro:IPR043170|rcsb pdb:2IXO|rcsb pdb:2IXP|sgd:YIL153W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:sVB0aA6yibWUx/d2SE+pwpKKgtI9606	rogid:It2q8WlpmvLEZ1fqpRF5Fypw9Q4559292	intact-crc:5192BBEE93303ECC|rigid:KsVct/YV1zMOa+Ebr+FAG0MIZPE	false	sufficient binding region:82-400	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:A2A369	uniprotkb:P40454	intact:EBI-11530808|ensembl:ENSP00000371766	intact:EBI-25278|uniprotkb:D6VVD4|ensemblfungi:YIL153W	psi-mi:a2a369_human(display_long)|uniprotkb:DOCK8(gene name)|psi-mi:DOCK8(display_short)	psi-mi:ptpa1_yeast(display_long)|uniprotkb:YIL153W(locus name)|uniprotkb:RRD1(gene name)|psi-mi:RRD1(display_short)|uniprotkb:NCS1(gene name synonym)|uniprotkb:YPA1(gene name synonym)|uniprotkb:Peptidyl-prolyl cis-trans isomerase PTPA-1(gene name synonym)|uniprotkb:Phosphotyrosyl phosphatase activator 1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11530871|imex:IM-24995-893	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000107099(gene)|ensembl:ENST00000382329(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0007264"(small GTPase mediated signal transduction)|interpro:IPR010703(Dedicator of cytokinesis)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026791|interpro:IPR027007|interpro:IPR027357|interpro:IPR035892|interpro:IPR043161|interpro:IPR043162|entrezgene/locuslink:81704(identity)	refseq:NP_012113.1|sgd:S000001415|mint:P40454|dip:DIP-5663N|ensemblfungi:YIL153W(gene)|ensemblfungi:YIL153W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006914"(autophagy)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008160"(protein tyrosine phosphatase activator activity)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0043618"(regulation of transcription from RNA polymerase II promoter in response to stress)|interpro:IPR004327(Phosphotyrosyl phosphatase activator, PTPA)|interpro:IPR037218|interpro:IPR043170|rcsb pdb:2IXO|rcsb pdb:2IXP|sgd:YIL153W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Sa5ulmmVxrpxZ+GAhN64RAHXYdk9606	rogid:It2q8WlpmvLEZ1fqpRF5Fypw9Q4559292	intact-crc:D34BBC59B3BD25E6|rigid:BRPqghNdVaxCkDOG5Xsw8yD+iLA	false	sufficient binding region:1054-1566	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q15645	uniprotkb:P40446	intact:EBI-358993|uniprotkb:C9K0T3|uniprotkb:O15324|ensembl:ENSP00000166345|uniprotkb:D3DTC0	intact:EBI-11530862|uniprotkb:D6VVC2|uniprotkb:Q05730|ensemblfungi:YIL165C	psi-mi:pch2_human(display_long)|uniprotkb:TRIP13(gene name)|psi-mi:TRIP13(display_short)|uniprotkb:Thyroid receptor-interacting protein 13(gene name synonym)|uniprotkb:PCH2(gene name synonym)|uniprotkb:Thyroid hormone receptor interactor 13(gene name synonym)|uniprotkb:Human papillomavirus type 16 E1 protein-binding protein(gene name synonym)	psi-mi:yiq5_yeast(display_long)|uniprotkb:YI9402.10AC(orf name)|uniprotkb:YIL165C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11530860|imex:IM-24995-892	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004228.1|ensembl:ENSG00000071539(gene)|ensembl:ENST00000166345(transcript)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|refseq:XP_011512465.1|dip:DIP-34493N|go:"GO:0005694"(chromosome)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0007141"(male meiosis I)|go:"GO:0007144"(female meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007286"(spermatid development)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051598"(meiotic recombination checkpoint signaling)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR027417|interpro:IPR044539|mint:Q15645|rcsb pdb:5VQ9|rcsb pdb:5VQA|rcsb pdb:5WC2|rcsb pdb:6F0X|rcsb pdb:6LK0|rcsb pdb:7L9P|entrezgene/locuslink:9319(identity)	interpro:IPR003010(Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase)|refseq:NP_012101.1|sgd:S000001427|interpro:IPR044149|ensemblfungi:YIL165C(gene)|ensemblfungi:YIL165C_mRNA(transcript)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0003824"(catalytic activity)|go:"GO:0006807"(nitrogen compound metabolic process)|go:"GO:0016236"(macroautophagy)|interpro:IPR036526|sgd:YIL165C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/03/16	rogid:heF2f3R2lGIpZ80mZHnhMktXTE49606	rogid:5G/EX7rlenWVlKfGQdYrkSF26Lw559292	intact-crc:444100A6291588F7|rigid:tQ+Lq4y8f+dGePQC1yTsxnbJor4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O96006	uniprotkb:P40454	intact:EBI-740037|uniprotkb:Q96BY4|ensembl:ENSP00000370616|ensembl:ENSP00000370620|ensembl:ENSP00000370621|ensembl:ENSP00000498725	intact:EBI-25278|uniprotkb:D6VVD4|ensemblfungi:YIL153W	psi-mi:zbed1_human(display_long)|uniprotkb:ZBED1(gene name)|psi-mi:ZBED1(display_short)|uniprotkb:ALTE(gene name synonym)|uniprotkb:DREF(gene name synonym)|uniprotkb:KIAA0785(gene name synonym)|uniprotkb:TRAMP(gene name synonym)|uniprotkb:dREF homolog(gene name synonym)|uniprotkb:Putative Ac-like transposable element(gene name synonym)|uniprotkb:DNA replication-related element-binding factor(gene name synonym)|uniprotkb:Zinc finger BED domain-containing protein 1(gene name synonym)|uniprotkb:hDREF(gene name synonym)	psi-mi:ptpa1_yeast(display_long)|uniprotkb:YIL153W(locus name)|uniprotkb:RRD1(gene name)|psi-mi:RRD1(display_short)|uniprotkb:NCS1(gene name synonym)|uniprotkb:YPA1(gene name synonym)|uniprotkb:Peptidyl-prolyl cis-trans isomerase PTPA-1(gene name synonym)|uniprotkb:Phosphotyrosyl phosphatase activator 1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11530913|imex:IM-24995-897	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164606.1|refseq:NP_001164607.1|refseq:NP_004720.1|ensembl:ENSG00000214717(gene)|ensembl:ENST00000381218(transcript)|ensembl:ENST00000381222(transcript)|ensembl:ENST00000381223(transcript)|ensembl:ENST00000652001(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0031965"(nuclear membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044828"(negative regulation by host of viral genome replication)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0061665"(SUMO ligase activity)|go:"GO:1990466"(protein autosumoylation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003656(Zinc finger, BED-type predicted)|interpro:IPR008906(HAT dimerisation)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR036236|mint:O96006|rcsb pdb:2CT5|reactome:R-HSA-4551638|go:"GO:0005813"(centrosome)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016605"(PML body)|entrezgene/locuslink:9189(identity)	refseq:NP_012113.1|sgd:S000001415|mint:P40454|dip:DIP-5663N|ensemblfungi:YIL153W(gene)|ensemblfungi:YIL153W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006914"(autophagy)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008160"(protein tyrosine phosphatase activator activity)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0043618"(regulation of transcription from RNA polymerase II promoter in response to stress)|interpro:IPR004327(Phosphotyrosyl phosphatase activator, PTPA)|interpro:IPR037218|interpro:IPR043170|rcsb pdb:2IXO|rcsb pdb:2IXP|sgd:YIL153W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:jl97ZV2Kz5YAmQKktWt/wk7OkRw9606	rogid:It2q8WlpmvLEZ1fqpRF5Fypw9Q4559292	intact-crc:9FF28DC8099D1F7F|rigid:ZLGqKYVB2VfqEsWkHOH+FzojGYI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O76083-2	uniprotkb:P40454	intact:EBI-11524542|ensembl:ENSP00000335242	intact:EBI-25278|uniprotkb:D6VVD4|ensemblfungi:YIL153W	psi-mi:o76083-2(display_long)|uniprotkb:PDE9A(gene name)|psi-mi:PDE9A(display_short)	psi-mi:ptpa1_yeast(display_long)|uniprotkb:YIL153W(locus name)|uniprotkb:RRD1(gene name)|psi-mi:RRD1(display_short)|uniprotkb:NCS1(gene name synonym)|uniprotkb:YPA1(gene name synonym)|uniprotkb:Peptidyl-prolyl cis-trans isomerase PTPA-1(gene name synonym)|uniprotkb:Phosphotyrosyl phosphatase activator 1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11530904|imex:IM-24995-896	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-742764(isoform-parent)|ensembl:ENSG00000160191(gene)|ensembl:ENST00000335512(transcript)|uniprotkb:O76083-2(isoform-parent)|entrezgene/locuslink:5152(identity)	refseq:NP_012113.1|sgd:S000001415|mint:P40454|dip:DIP-5663N|ensemblfungi:YIL153W(gene)|ensemblfungi:YIL153W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006914"(autophagy)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008160"(protein tyrosine phosphatase activator activity)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0043618"(regulation of transcription from RNA polymerase II promoter in response to stress)|interpro:IPR004327(Phosphotyrosyl phosphatase activator, PTPA)|interpro:IPR037218|interpro:IPR043170|rcsb pdb:2IXO|rcsb pdb:2IXP|sgd:YIL153W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:nTzgeYGOwTM/7VJUgxSnlnDiCFo9606	rogid:It2q8WlpmvLEZ1fqpRF5Fypw9Q4559292	intact-crc:DBF8F29200B15C8F|rigid:BXZw2vFztuNWbIemzOgAazbzMhk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40454	uniprotkb:O15156-2	intact:EBI-25278|uniprotkb:D6VVD4|ensemblfungi:YIL153W	intact:EBI-11522250|ensembl:ENSP00000406286	psi-mi:ptpa1_yeast(display_long)|uniprotkb:YIL153W(locus name)|uniprotkb:RRD1(gene name)|psi-mi:RRD1(display_short)|uniprotkb:NCS1(gene name synonym)|uniprotkb:YPA1(gene name synonym)|uniprotkb:Peptidyl-prolyl cis-trans isomerase PTPA-1(gene name synonym)|uniprotkb:Phosphotyrosyl phosphatase activator 1(gene name synonym)	psi-mi:o15156-2(display_long)|uniprotkb:ZBTB7B(gene name)|psi-mi:ZBTB7B(display_short)|uniprotkb:Krueppel-related zinc finger protein cKrox(gene name synonym)|uniprotkb:T-helper-inducing POZ/Krueppel-like factor(gene name synonym)|uniprotkb:ZBTB15(gene name synonym)|uniprotkb:ZFP67(gene name synonym)|uniprotkb:ZNF857B(gene name synonym)|uniprotkb:Zinc finger and BTB domain-containing protein 15(gene name synonym)|uniprotkb:Zinc finger protein 67 homolog(gene name synonym)|uniprotkb:Zinc finger protein 857B(gene name synonym)|uniprotkb:Zinc finger protein Th-POK(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11530893|imex:IM-24995-895	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012113.1|sgd:S000001415|mint:P40454|dip:DIP-5663N|ensemblfungi:YIL153W(gene)|ensemblfungi:YIL153W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006914"(autophagy)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008160"(protein tyrosine phosphatase activator activity)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0043618"(regulation of transcription from RNA polymerase II promoter in response to stress)|interpro:IPR004327(Phosphotyrosyl phosphatase activator, PTPA)|interpro:IPR037218|interpro:IPR043170|rcsb pdb:2IXO|rcsb pdb:2IXP|sgd:YIL153W(identity)	intact:EBI-740434(isoform-parent)|ensembl:ENSG00000160685(gene)|ensembl:ENST00000417934(transcript)|uniprotkb:O15156-2(isoform-parent)|entrezgene/locuslink:51043(identity)	-	-	isoform-comment:No experimental confirmation available.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:It2q8WlpmvLEZ1fqpRF5Fypw9Q4559292	rogid:41NEFYyprTXI+fOHVFh78TPKF289606	intact-crc:56F1C0A7630F459F|rigid:Mt7Tv9gZQn2oR/jTpxqKaeswQOg	false	-	sufficient binding region:35-573	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40454	uniprotkb:P19012	intact:EBI-25278|uniprotkb:D6VVD4|ensemblfungi:YIL153W	intact:EBI-739566|uniprotkb:Q53XV8|uniprotkb:Q9BUG4|uniprotkb:B3KQY1|uniprotkb:B3KRA2|uniprotkb:E0CX14|ensembl:ENSP00000254043|ensembl:ENSP00000377546	psi-mi:ptpa1_yeast(display_long)|uniprotkb:YIL153W(locus name)|uniprotkb:RRD1(gene name)|psi-mi:RRD1(display_short)|uniprotkb:NCS1(gene name synonym)|uniprotkb:YPA1(gene name synonym)|uniprotkb:Peptidyl-prolyl cis-trans isomerase PTPA-1(gene name synonym)|uniprotkb:Phosphotyrosyl phosphatase activator 1(gene name synonym)	psi-mi:k1c15_human(display_long)|uniprotkb:KRT15(gene name)|psi-mi:KRT15(display_short)|uniprotkb:KRTB(gene name synonym)|uniprotkb:Cytokeratin-15(gene name synonym)|uniprotkb:Keratin-15(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11530940|imex:IM-24995-900	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012113.1|sgd:S000001415|mint:P40454|dip:DIP-5663N|ensemblfungi:YIL153W(gene)|ensemblfungi:YIL153W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006914"(autophagy)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008160"(protein tyrosine phosphatase activator activity)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0043618"(regulation of transcription from RNA polymerase II promoter in response to stress)|interpro:IPR004327(Phosphotyrosyl phosphatase activator, PTPA)|interpro:IPR037218|interpro:IPR043170|rcsb pdb:2IXO|rcsb pdb:2IXP|sgd:YIL153W(identity)	refseq:NP_002266.2|ensembl:ENSG00000171346(gene)|ensembl:ENST00000254043(transcript)|ensembl:ENST00000393976(transcript)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0008544"(epidermis development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097110"(scaffold protein binding)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR039008|mint:P19012|reactome:R-HSA-6805567|reactome:R-HSA-6809371|entrezgene/locuslink:3866(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:It2q8WlpmvLEZ1fqpRF5Fypw9Q4559292	rogid:WrZQBYQvrWcfrR5ojWXrXp6spPE9606	intact-crc:A5CCA432216BE10F|rigid:aA/Wb4gvWPLiwm3Mr6RMszphK/8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40454	uniprotkb:P15531	intact:EBI-25278|uniprotkb:D6VVD4|ensemblfungi:YIL153W	intact:EBI-741141|ensembl:ENSP00000376892|uniprotkb:Q6FGK3|uniprotkb:Q86XQ2|uniprotkb:Q9UDJ6	psi-mi:ptpa1_yeast(display_long)|uniprotkb:YIL153W(locus name)|uniprotkb:RRD1(gene name)|psi-mi:RRD1(display_short)|uniprotkb:NCS1(gene name synonym)|uniprotkb:YPA1(gene name synonym)|uniprotkb:Peptidyl-prolyl cis-trans isomerase PTPA-1(gene name synonym)|uniprotkb:Phosphotyrosyl phosphatase activator 1(gene name synonym)	psi-mi:ndka_human(display_long)|uniprotkb:Tumor metastatic process-associated protein(gene name synonym)|uniprotkb:Metastasis inhibition factor nm23(gene name synonym)|uniprotkb:Granzyme A-activated DNase(gene name synonym)|uniprotkb:NME1(gene name)|psi-mi:NME1(display_short)|uniprotkb:NDPKA(gene name synonym)|uniprotkb:NM23(gene name synonym)|uniprotkb:NM23-H1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11530931|imex:IM-24995-899	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012113.1|sgd:S000001415|mint:P40454|dip:DIP-5663N|ensemblfungi:YIL153W(gene)|ensemblfungi:YIL153W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006914"(autophagy)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008160"(protein tyrosine phosphatase activator activity)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0043618"(regulation of transcription from RNA polymerase II promoter in response to stress)|interpro:IPR004327(Phosphotyrosyl phosphatase activator, PTPA)|interpro:IPR037218|interpro:IPR043170|rcsb pdb:2IXO|rcsb pdb:2IXP|sgd:YIL153W(identity)	refseq:NP_000260.1|refseq:NP_937818.1|ensembl:ENSG00000239672(gene)|ensembl:ENST00000393196(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0002762"(negative regulation of myeloid leukocyte differentiation)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004536"(deoxyribonuclease activity)|go:"GO:0004550"(nucleoside diphosphate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0006183"(GTP biosynthetic process)|go:"GO:0006228"(UTP biosynthetic process)|go:"GO:0006241"(CTP biosynthetic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007595"(lactation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014075"(response to amine)|go:"GO:0016020"(membrane)|go:"GO:0019215"(intermediate filament binding)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051591"(response to cAMP)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071398"(cellular response to fatty acid)|interpro:IPR001564(Nucleoside diphosphate kinase, core)|go:"GO:0019899"(enzyme binding)|interpro:IPR023005|go:"GO:0021766"(hippocampus development)|interpro:IPR034907|interpro:IPR036850|mint:P15531|go:"GO:0030154"(cell differentiation)|go:"GO:0032587"(ruffle membrane)|rcsb pdb:1JXV|rcsb pdb:1UCN|go:"GO:0033574"(response to testosterone)|go:"GO:0035690"|rcsb pdb:2HVD|rcsb pdb:2HVE|rcsb pdb:3L7U|rcsb pdb:4ENO|rcsb pdb:5UI4|reactome:R-HSA-499943|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043024"(ribosomal small subunit binding)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|dip:DIP-39164N|entrezgene/locuslink:4830(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:It2q8WlpmvLEZ1fqpRF5Fypw9Q4559292	rogid:Ut4gK1Xq786CaZzvqdS1eiU5op89606	intact-crc:F50F4E14DA36AA5D|rigid:kIJctXvQmDZgb6/CHGf4titKCK0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P14373	uniprotkb:P40454	intact:EBI-719493|uniprotkb:A2BE15|uniprotkb:Q5RJA8|uniprotkb:Q5ST26|uniprotkb:Q6LA73|uniprotkb:Q6NXR9|uniprotkb:Q9BZY6|uniprotkb:Q9UJL3|ensembl:ENSP00000383555|ensembl:ENSP00000392787|ensembl:ENSP00000405229|ensembl:ENSP00000414793|ensembl:ENSP00000366404	intact:EBI-25278|uniprotkb:D6VVD4|ensemblfungi:YIL153W	psi-mi:tri27_human(display_long)|uniprotkb:TRIM27(gene name)|psi-mi:TRIM27(display_short)|uniprotkb:RNF76(gene name synonym)|uniprotkb:RFP(gene name synonym)|uniprotkb:Ret finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 27(gene name synonym)|uniprotkb:RING finger protein 76(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM27(gene name synonym)	psi-mi:ptpa1_yeast(display_long)|uniprotkb:YIL153W(locus name)|uniprotkb:RRD1(gene name)|psi-mi:RRD1(display_short)|uniprotkb:NCS1(gene name synonym)|uniprotkb:YPA1(gene name synonym)|uniprotkb:Peptidyl-prolyl cis-trans isomerase PTPA-1(gene name synonym)|uniprotkb:Phosphotyrosyl phosphatase activator 1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11530922|imex:IM-24995-898	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006501.1|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0090281"(negative regulation of calcium ion import)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR020457|interpro:IPR035791|interpro:IPR043136|mint:P14373|reactome:R-HSA-3232142|reactome:R-HSA-9635465|reactome:R-HSA-8948751|ensembl:ENSG00000204713(gene)|ensembl:ENSG00000215641(gene)|ensembl:ENSG00000229006(gene)|ensembl:ENSG00000234495(gene)|ensembl:ENSG00000237071(gene)|ensembl:ENST00000377199(transcript)|ensembl:ENST00000400720(transcript)|ensembl:ENST00000431123(transcript)|ensembl:ENST00000435528(transcript)|ensembl:ENST00000437160(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001650"(fibrillar center)|go:"GO:0002820"(negative regulation of adaptive immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|entrezgene/locuslink:5987(identity)	refseq:NP_012113.1|sgd:S000001415|mint:P40454|dip:DIP-5663N|ensemblfungi:YIL153W(gene)|ensemblfungi:YIL153W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006914"(autophagy)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008160"(protein tyrosine phosphatase activator activity)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0043618"(regulation of transcription from RNA polymerase II promoter in response to stress)|interpro:IPR004327(Phosphotyrosyl phosphatase activator, PTPA)|interpro:IPR037218|interpro:IPR043170|rcsb pdb:2IXO|rcsb pdb:2IXP|sgd:YIL153W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:dsfH5OUghD8KSaTz1SFw9OYVTK49606	rogid:It2q8WlpmvLEZ1fqpRF5Fypw9Q4559292	intact-crc:27C0338DE3886B31|rigid:FT90KDDa2w97Bz5XrnlMMA3S8so	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P81877	uniprotkb:P40454	intact:EBI-748077|uniprotkb:Q8N2Q2|uniprotkb:Q9BWW6|uniprotkb:Q9Y4T7|uniprotkb:B7Z2L9|uniprotkb:E9PDA8|uniprotkb:B2R5W1|uniprotkb:B7Z1J2|uniprotkb:B7Z665|uniprotkb:D6RH18|uniprotkb:E9PB74|intact:EBI-28967061|ensembl:ENSP00000322977	intact:EBI-25278|uniprotkb:D6VVD4|ensemblfungi:YIL153W	psi-mi:ssbp2_human(display_long)|uniprotkb:Sequence-specific single-stranded-DNA-binding protein 2(gene name synonym)|uniprotkb:SSBP2(gene name)|psi-mi:SSBP2(display_short)|uniprotkb:SSDP2(gene name synonym)	psi-mi:ptpa1_yeast(display_long)|uniprotkb:YIL153W(locus name)|uniprotkb:RRD1(gene name)|psi-mi:RRD1(display_short)|uniprotkb:NCS1(gene name synonym)|uniprotkb:YPA1(gene name synonym)|uniprotkb:Peptidyl-prolyl cis-trans isomerase PTPA-1(gene name synonym)|uniprotkb:Phosphotyrosyl phosphatase activator 1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11530976|imex:IM-24995-904	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000322977|ensembl:ENST00000505980|ensembl:ENSP00000423969|ensembl:ENST00000509053|ensembl:ENSP00000422961|ensembl:ENST00000514493|ensembl:ENSP00000426183|ensembl:ENST00000515395|ensembl:ENSP00000424657|refseq:NP_001243661.1|refseq:NP_036578.2|refseq:NP_001243665.1|refseq:NP_001243663.1|refseq:NP_001243664.1|refseq:NP_001243662.1|ensembl:ENSG00000145687(gene)|ensembl:ENST00000320672(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR008116(Sequence-specific single-strand DNA-binding protein)|mint:P81877|rcsb pdb:6IWV|rcsb pdb:6TYD|dip:DIP-29459N|entrezgene/locuslink:23635(identity)	refseq:NP_012113.1|sgd:S000001415|mint:P40454|dip:DIP-5663N|ensemblfungi:YIL153W(gene)|ensemblfungi:YIL153W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006914"(autophagy)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008160"(protein tyrosine phosphatase activator activity)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0043618"(regulation of transcription from RNA polymerase II promoter in response to stress)|interpro:IPR004327(Phosphotyrosyl phosphatase activator, PTPA)|interpro:IPR037218|interpro:IPR043170|rcsb pdb:2IXO|rcsb pdb:2IXP|sgd:YIL153W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:CMmZPTurp1G6Y2q7GP/pTMlFM549606	rogid:It2q8WlpmvLEZ1fqpRF5Fypw9Q4559292	intact-crc:88CB58FCAB8A55E4|rigid:GhV/GnLYK6m7wnyOqY+K5wXl64s	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40454	uniprotkb:P48775	intact:EBI-25278|uniprotkb:D6VVD4|ensemblfungi:YIL153W	intact:EBI-743494|ensembl:ENSP00000444788|ensembl:ENSP00000460086|uniprotkb:A8K053	psi-mi:ptpa1_yeast(display_long)|uniprotkb:YIL153W(locus name)|uniprotkb:RRD1(gene name)|psi-mi:RRD1(display_short)|uniprotkb:NCS1(gene name synonym)|uniprotkb:YPA1(gene name synonym)|uniprotkb:Peptidyl-prolyl cis-trans isomerase PTPA-1(gene name synonym)|uniprotkb:Phosphotyrosyl phosphatase activator 1(gene name synonym)	psi-mi:t23o_human(display_long)|uniprotkb:Tryptophan pyrrolase(gene name synonym)|uniprotkb:Tryptophan oxygenase(gene name synonym)|uniprotkb:Tryptamin 2,3-dioxygenase(gene name synonym)|uniprotkb:TDO2(gene name)|psi-mi:TDO2(display_short)|uniprotkb:TDO(gene name synonym)|uniprotkb:Tryptophanase(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11530967|imex:IM-24995-903	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012113.1|sgd:S000001415|mint:P40454|dip:DIP-5663N|ensemblfungi:YIL153W(gene)|ensemblfungi:YIL153W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006914"(autophagy)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008160"(protein tyrosine phosphatase activator activity)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0043618"(regulation of transcription from RNA polymerase II promoter in response to stress)|interpro:IPR004327(Phosphotyrosyl phosphatase activator, PTPA)|interpro:IPR037218|interpro:IPR043170|rcsb pdb:2IXO|rcsb pdb:2IXP|sgd:YIL153W(identity)	ensembl:ENSG00000151790(gene)|ensembl:ENSG00000262635(gene)|ensembl:ENST00000536354(transcript)|ensembl:ENST00000573403(transcript)|go:"GO:0004833"(tryptophan 2,3-dioxygenase activity)|go:"GO:0005829"(cytosol)|go:"GO:0016597"(amino acid binding)|go:"GO:0019441"(tryptophan catabolic process to kynurenine)|go:"GO:0019442"(tryptophan catabolic process to acetyl-CoA)|go:"GO:0019825"(oxygen binding)|go:"GO:0020037"(heme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051289"(protein homotetramerization)|go:"GO:1904842"(response to nitroglycerin)|interpro:IPR004981(Tryptophan 2,3-dioxygenase)|interpro:IPR037217|mint:P48775|rcsb pdb:4PW8|rcsb pdb:5TI9|rcsb pdb:5TIA|rcsb pdb:6A4I|rcsb pdb:6PYY|rcsb pdb:6PYZ|rcsb pdb:6UD5|rcsb pdb:6VBN|reactome:R-HSA-71240|refseq:NP_005642.1|entrezgene/locuslink:6999(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:It2q8WlpmvLEZ1fqpRF5Fypw9Q4559292	rogid:S+cyc710I52nIFQWgKhXFul9QZw9606	intact-crc:AF74C9D9AE35F2E5|rigid:t7CR6F0wQMIWVXG7RAozbNhJ+N0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40454	uniprotkb:P38432	intact:EBI-25278|uniprotkb:D6VVD4|ensemblfungi:YIL153W	intact:EBI-945751|uniprotkb:B2R931|ensembl:ENSP00000240316	psi-mi:ptpa1_yeast(display_long)|uniprotkb:YIL153W(locus name)|uniprotkb:RRD1(gene name)|psi-mi:RRD1(display_short)|uniprotkb:NCS1(gene name synonym)|uniprotkb:YPA1(gene name synonym)|uniprotkb:Peptidyl-prolyl cis-trans isomerase PTPA-1(gene name synonym)|uniprotkb:Phosphotyrosyl phosphatase activator 1(gene name synonym)	psi-mi:coil_human(display_long)|uniprotkb:COIL(gene name)|psi-mi:COIL(display_short)|uniprotkb:CLN80(gene name synonym)|uniprotkb:p80-coilin(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11530958|imex:IM-24995-902	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012113.1|sgd:S000001415|mint:P40454|dip:DIP-5663N|ensemblfungi:YIL153W(gene)|ensemblfungi:YIL153W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006914"(autophagy)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008160"(protein tyrosine phosphatase activator activity)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0043618"(regulation of transcription from RNA polymerase II promoter in response to stress)|interpro:IPR004327(Phosphotyrosyl phosphatase activator, PTPA)|interpro:IPR037218|interpro:IPR043170|rcsb pdb:2IXO|rcsb pdb:2IXP|sgd:YIL153W(identity)	refseq:NP_004636.1|dip:DIP-38503N|ensembl:ENSG00000121058(gene)|ensembl:ENST00000240316(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0015030"(Cajal body)|go:"GO:0016020"(membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0030619"(U1 snRNA binding)|go:"GO:0030620"(U2 snRNA binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR024822|interpro:IPR031722|mint:P38432|entrezgene/locuslink:8161(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:It2q8WlpmvLEZ1fqpRF5Fypw9Q4559292	rogid:hd5p6AbyA/GYNEeca99Mdb41qM09606	intact-crc:4DD9F98F35A8AE71|rigid:9BOWBg6pGUDiRMnXq/IwLYKkyEQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40454	uniprotkb:P35638	intact:EBI-25278|uniprotkb:D6VVD4|ensemblfungi:YIL153W	intact:EBI-742651|ensembl:ENSP00000340671|ensembl:ENSP00000447188|ensembl:ENSP00000494844|uniprotkb:F8VS99	psi-mi:ptpa1_yeast(display_long)|uniprotkb:YIL153W(locus name)|uniprotkb:RRD1(gene name)|psi-mi:RRD1(display_short)|uniprotkb:NCS1(gene name synonym)|uniprotkb:YPA1(gene name synonym)|uniprotkb:Peptidyl-prolyl cis-trans isomerase PTPA-1(gene name synonym)|uniprotkb:Phosphotyrosyl phosphatase activator 1(gene name synonym)	psi-mi:ddit3_human(display_long)|uniprotkb:CHOP10(gene name synonym)|uniprotkb:C/EBP-homologous protein(gene name synonym)|uniprotkb:DDIT3(gene name)|psi-mi:DDIT3(display_short)|uniprotkb:CHOP(gene name synonym)|uniprotkb:GADD153(gene name synonym)|uniprotkb:Growth arrest and DNA damage-inducible protein GADD153(gene name synonym)|uniprotkb:C/EBP-homologous protein 10(gene name synonym)|uniprotkb:C/EBP zeta(gene name synonym)|uniprotkb:CCAAT/enhancer-binding protein homologous protein(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11530949|imex:IM-24995-901	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012113.1|sgd:S000001415|mint:P40454|dip:DIP-5663N|ensemblfungi:YIL153W(gene)|ensemblfungi:YIL153W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006914"(autophagy)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008160"(protein tyrosine phosphatase activator activity)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0043618"(regulation of transcription from RNA polymerase II promoter in response to stress)|interpro:IPR004327(Phosphotyrosyl phosphatase activator, PTPA)|interpro:IPR037218|interpro:IPR043170|rcsb pdb:2IXO|rcsb pdb:2IXP|sgd:YIL153W(identity)	refseq:NP_001181986.1|refseq:NP_004074.2|refseq:NP_001181982.1|refseq:NP_001181983.1|refseq:NP_001181984.1|ensembl:ENSG00000175197(gene)|go:"GO:0001955"(blood vessel maturation)|ensembl:ENST00000346473(transcript)|ensembl:ENST00000547303(transcript)|ensembl:ENST00000623876(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003677"(DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032792"(negative regulation of CREB transcription factor activity)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0036488"(CHOP-C/EBP complex)|go:"GO:0036499"(PERK-mediated unfolded protein response)|go:"GO:0036500"(ATF6-mediated unfolded protein response)|go:"GO:0042594"(response to starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0032713"(negative regulation of interleukin-4 production)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006983"(ER overload response)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0007049"(cell cycle)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008140"(cAMP response element binding protein binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0005737"(cytoplasm)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0005770"(late endosome)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032700"(negative regulation of interleukin-17 production)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0072655"(establishment of protein localization to mitochondrion)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0140416"(transcription regulator inhibitor activity)|go:"GO:1902237"(positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903026"(negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990442"(intrinsic apoptotic signaling pathway in response to nitrosative stress)|go:"GO:1990617"(CHOP-ATF4 complex)|go:"GO:1990622"(CHOP-ATF3 complex)|go:"GO:2000016"(negative regulation of determination of dorsal identity)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR016670(DNA damage-inducible transcript 3)|mint:P35638|reactome:R-HSA-380994|reactome:R-HSA-381183|reactome:R-HSA-9614657|reactome:R-HSA-9633012|reactome:R-HSA-9648895|go:"GO:0043618"(regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045662"(negative regulation of myoblast differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|dip:DIP-41589N|entrezgene/locuslink:1649(identity)	-	-	crc64:31905293FB1FBBE2	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:It2q8WlpmvLEZ1fqpRF5Fypw9Q4559292	rogid:xyMsMwPwid+S2IYb3H0K0pnUc309606	intact-crc:CBFDB572D616F539|rigid:Jatb23/ICmSYg9k66GVVJQSkuTs	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8NHQ1	uniprotkb:P40454	intact:EBI-739624|ensembl:ENSP00000264982|ensembl:ENSP00000419231|uniprotkb:Q96B31|uniprotkb:Q9H2C3|uniprotkb:Q9H2Z1|uniprotkb:Q9H940|uniprotkb:D3DNE9|uniprotkb:B7Z5I8|uniprotkb:B7Z7E8|uniprotkb:F5GZX8	intact:EBI-25278|uniprotkb:D6VVD4|ensemblfungi:YIL153W	psi-mi:cep70_human(display_long)|uniprotkb:CEP70(gene name)|psi-mi:CEP70(display_short)|uniprotkb:BITE(gene name synonym)|uniprotkb:p10-binding protein(gene name synonym)	psi-mi:ptpa1_yeast(display_long)|uniprotkb:YIL153W(locus name)|uniprotkb:RRD1(gene name)|psi-mi:RRD1(display_short)|uniprotkb:NCS1(gene name synonym)|uniprotkb:YPA1(gene name synonym)|uniprotkb:Peptidyl-prolyl cis-trans isomerase PTPA-1(gene name synonym)|uniprotkb:Phosphotyrosyl phosphatase activator 1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11531014|imex:IM-24995-908	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114107(gene)|ensembl:ENST00000264982(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|interpro:IPR019734|interpro:IPR037692|mint:Q8NHQ1|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|ensembl:ENST00000484888(transcript)|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_077817.2|refseq:XP_016862764.1|refseq:NP_001275893.1|refseq:NP_001275894.1|refseq:NP_001275895.1|refseq:NP_001275896.1|refseq:NP_001307527.1|refseq:NP_001307529.1|entrezgene/locuslink:80321(identity)	refseq:NP_012113.1|sgd:S000001415|mint:P40454|dip:DIP-5663N|ensemblfungi:YIL153W(gene)|ensemblfungi:YIL153W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006914"(autophagy)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008160"(protein tyrosine phosphatase activator activity)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0043618"(regulation of transcription from RNA polymerase II promoter in response to stress)|interpro:IPR004327(Phosphotyrosyl phosphatase activator, PTPA)|interpro:IPR037218|interpro:IPR043170|rcsb pdb:2IXO|rcsb pdb:2IXP|sgd:YIL153W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:S4yveQWcvdVtAUX65gqrJ5Dv0Mc9606	rogid:It2q8WlpmvLEZ1fqpRF5Fypw9Q4559292	intact-crc:C93EBF0ADA3194A0|rigid:xt0sTaF6qMCpURJuIBUzQiFieOM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40454	uniprotkb:Q8NA61-2	intact:EBI-25278|uniprotkb:D6VVD4|ensemblfungi:YIL153W	intact:EBI-11524851|ensembl:ENSP00000368249|ensembl:ENSP00000480148	psi-mi:ptpa1_yeast(display_long)|uniprotkb:YIL153W(locus name)|uniprotkb:RRD1(gene name)|psi-mi:RRD1(display_short)|uniprotkb:NCS1(gene name synonym)|uniprotkb:YPA1(gene name synonym)|uniprotkb:Peptidyl-prolyl cis-trans isomerase PTPA-1(gene name synonym)|uniprotkb:Phosphotyrosyl phosphatase activator 1(gene name synonym)	psi-mi:q8na61-2(display_long)|uniprotkb:CBY2(gene name)|psi-mi:CBY2(display_short)|uniprotkb:SPERT(gene name synonym)|uniprotkb:Spermatid-associated protein(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11531005|imex:IM-24995-907	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012113.1|sgd:S000001415|mint:P40454|dip:DIP-5663N|ensemblfungi:YIL153W(gene)|ensemblfungi:YIL153W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006914"(autophagy)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008160"(protein tyrosine phosphatase activator activity)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0043618"(regulation of transcription from RNA polymerase II promoter in response to stress)|interpro:IPR004327(Phosphotyrosyl phosphatase activator, PTPA)|interpro:IPR037218|interpro:IPR043170|rcsb pdb:2IXO|rcsb pdb:2IXP|sgd:YIL153W(identity)	intact:EBI-741724(isoform-parent)|ensembl:ENSG00000174015(gene)|ensembl:ENST00000378966(transcript)|ensembl:ENST00000610924(transcript)|uniprotkb:Q8NA61-2(isoform-parent)|entrezgene/locuslink:220082(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:It2q8WlpmvLEZ1fqpRF5Fypw9Q4559292	rogid:SogYcXGGMYRYzB9xKC5o0pEtsDs9606	intact-crc:F280FB7CCA98800E|rigid:bQV0FaOfr/y8MZEI89atVwxZAjI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8N7W2-2	uniprotkb:P40454	intact:EBI-10181188|ensembl:ENSP00000367868	intact:EBI-25278|uniprotkb:D6VVD4|ensemblfungi:YIL153W	psi-mi:q8n7w2-2(display_long)|uniprotkb:C10orf30(gene name synonym)|uniprotkb:BEND7(gene name)|psi-mi:BEND7(display_short)	psi-mi:ptpa1_yeast(display_long)|uniprotkb:YIL153W(locus name)|uniprotkb:RRD1(gene name)|psi-mi:RRD1(display_short)|uniprotkb:NCS1(gene name synonym)|uniprotkb:YPA1(gene name synonym)|uniprotkb:Peptidyl-prolyl cis-trans isomerase PTPA-1(gene name synonym)|uniprotkb:Phosphotyrosyl phosphatase activator 1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11530994|imex:IM-24995-906	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000165626(gene)|ensembl:ENST00000378605(transcript)|intact:EBI-743382(isoform-parent)|uniprotkb:Q8N7W2-2(isoform-parent)|entrezgene/locuslink:222389(identity)	refseq:NP_012113.1|sgd:S000001415|mint:P40454|dip:DIP-5663N|ensemblfungi:YIL153W(gene)|ensemblfungi:YIL153W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006914"(autophagy)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008160"(protein tyrosine phosphatase activator activity)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0043618"(regulation of transcription from RNA polymerase II promoter in response to stress)|interpro:IPR004327(Phosphotyrosyl phosphatase activator, PTPA)|interpro:IPR037218|interpro:IPR043170|rcsb pdb:2IXO|rcsb pdb:2IXP|sgd:YIL153W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:p6qrTn80hLyVU0W2Tvwn50Q4m5I9606	rogid:It2q8WlpmvLEZ1fqpRF5Fypw9Q4559292	intact-crc:8B82E7F042E7C654|rigid:8uzaz0eS8i/AV8eTSZYTcOFuBWY	false	sufficient binding region:10-374	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40454	uniprotkb:Q5JR59-3	intact:EBI-25278|uniprotkb:D6VVD4|ensemblfungi:YIL153W	intact:EBI-11522433|ensembl:ENSP00000370186	psi-mi:ptpa1_yeast(display_long)|uniprotkb:YIL153W(locus name)|uniprotkb:RRD1(gene name)|psi-mi:RRD1(display_short)|uniprotkb:NCS1(gene name synonym)|uniprotkb:YPA1(gene name synonym)|uniprotkb:Peptidyl-prolyl cis-trans isomerase PTPA-1(gene name synonym)|uniprotkb:Phosphotyrosyl phosphatase activator 1(gene name synonym)	psi-mi:q5jr59-3(display_long)|uniprotkb:MTUS2(gene name)|psi-mi:MTUS2(display_short)|uniprotkb:CAZIP(gene name synonym)|uniprotkb:Cardiac zipper protein(gene name synonym)|uniprotkb:KIAA0774(gene name synonym)|uniprotkb:Microtubule plus-end tracking protein TIP150(gene name synonym)|uniprotkb:TIP150(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11530985|imex:IM-24995-905	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012113.1|sgd:S000001415|mint:P40454|dip:DIP-5663N|ensemblfungi:YIL153W(gene)|ensemblfungi:YIL153W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006914"(autophagy)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008160"(protein tyrosine phosphatase activator activity)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0043618"(regulation of transcription from RNA polymerase II promoter in response to stress)|interpro:IPR004327(Phosphotyrosyl phosphatase activator, PTPA)|interpro:IPR037218|interpro:IPR043170|rcsb pdb:2IXO|rcsb pdb:2IXP|sgd:YIL153W(identity)	ensembl:ENSG00000132938(gene)|ensembl:ENST00000380808(transcript)|intact:EBI-742948(isoform-parent)|uniprotkb:Q5JR59-3(isoform-parent)|entrezgene/locuslink:23281(identity)	-	-	isoform-comment:No experimental confirmation available.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:It2q8WlpmvLEZ1fqpRF5Fypw9Q4559292	rogid:npId9tC7VoLN/jteoBiRbSYChPs9606	intact-crc:D33169D441C4650B|rigid:63HnY7CBz4Rqs48lh7DgOXN3Gxw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96CV9-2	uniprotkb:P40454	intact:EBI-9091423|ensembl:ENSP00000368027|ensembl:ENSP00000368040	intact:EBI-25278|uniprotkb:D6VVD4|ensemblfungi:YIL153W	psi-mi:q96cv9-2(display_long)|uniprotkb:E3-14.7K-interacting protein(gene name synonym)|uniprotkb:FIP-2(gene name synonym)|uniprotkb:FIP2(gene name synonym)|uniprotkb:GLC1E(gene name synonym)|uniprotkb:HIP7(gene name synonym)|uniprotkb:HYPL(gene name synonym)|uniprotkb:Huntingtin yeast partner L(gene name synonym)|uniprotkb:Huntingtin-interacting protein 7(gene name synonym)|uniprotkb:Huntingtin-interacting protein L(gene name synonym)|uniprotkb:NEMO-related protein(gene name synonym)|uniprotkb:NRP(gene name synonym)|uniprotkb:Optic neuropathy-inducing protein(gene name synonym)|uniprotkb:Transcription factor IIIA-interacting protein(gene name synonym)|uniprotkb:OPTN(gene name)|psi-mi:OPTN(display_short)	psi-mi:ptpa1_yeast(display_long)|uniprotkb:YIL153W(locus name)|uniprotkb:RRD1(gene name)|psi-mi:RRD1(display_short)|uniprotkb:NCS1(gene name synonym)|uniprotkb:YPA1(gene name synonym)|uniprotkb:Peptidyl-prolyl cis-trans isomerase PTPA-1(gene name synonym)|uniprotkb:Phosphotyrosyl phosphatase activator 1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11531041|imex:IM-24995-911	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-748974(isoform-parent)|ensembl:ENST00000378752(transcript)|ensembl:ENST00000378764(transcript)|ensembl:ENSG00000123240(gene)|uniprotkb:Q96CV9-2(isoform-parent)|entrezgene/locuslink:10133(identity)	refseq:NP_012113.1|sgd:S000001415|mint:P40454|dip:DIP-5663N|ensemblfungi:YIL153W(gene)|ensemblfungi:YIL153W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006914"(autophagy)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008160"(protein tyrosine phosphatase activator activity)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0043618"(regulation of transcription from RNA polymerase II promoter in response to stress)|interpro:IPR004327(Phosphotyrosyl phosphatase activator, PTPA)|interpro:IPR037218|interpro:IPR043170|rcsb pdb:2IXO|rcsb pdb:2IXP|sgd:YIL153W(identity)	-	isoform-comment:No experimental confirmation available.	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2018/04/06	rogid:ygzEQkiDJwDAMUuFQuOWsSIqwAk9606	rogid:It2q8WlpmvLEZ1fqpRF5Fypw9Q4559292	intact-crc:4526E800C152DFCF|rigid:Bmag+6huo34L9cXAp9+ovi4Xffs	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40454	uniprotkb:Q96CV9	intact:EBI-25278|uniprotkb:D6VVD4|ensemblfungi:YIL153W	intact:EBI-748974|uniprotkb:Q5T672|uniprotkb:Q5T673|uniprotkb:Q5T674|uniprotkb:Q5T675|uniprotkb:Q7LDL9|uniprotkb:Q8N562|uniprotkb:Q9UET9|uniprotkb:Q9UEV4|uniprotkb:Q9Y218|uniprotkb:B3KP00|uniprotkb:D3DRS4|uniprotkb:D3DRS8|ensembl:ENSP00000263036|ensembl:ENSP00000368021|ensembl:ENSP00000368022|ensembl:ENSP00000368032	psi-mi:ptpa1_yeast(display_long)|uniprotkb:YIL153W(locus name)|uniprotkb:RRD1(gene name)|psi-mi:RRD1(display_short)|uniprotkb:NCS1(gene name synonym)|uniprotkb:YPA1(gene name synonym)|uniprotkb:Peptidyl-prolyl cis-trans isomerase PTPA-1(gene name synonym)|uniprotkb:Phosphotyrosyl phosphatase activator 1(gene name synonym)	psi-mi:optn_human(display_long)|uniprotkb:HYPL(gene name synonym)|uniprotkb:Optic neuropathy-inducing protein(gene name synonym)|uniprotkb:E3-14.7K-interacting protein(gene name synonym)|uniprotkb:FIP-2(gene name synonym)|uniprotkb:Huntingtin-interacting protein L(gene name synonym)|uniprotkb:Huntingtin yeast partner L(gene name synonym)|uniprotkb:NEMO-related protein(gene name synonym)|uniprotkb:Transcription factor IIIA-interacting protein(gene name synonym)|uniprotkb:OPTN(gene name)|psi-mi:OPTN(display_short)|uniprotkb:FIP2(gene name synonym)|uniprotkb:GLC1E(gene name synonym)|uniprotkb:NRP(gene name synonym)|uniprotkb:HIP7(gene name synonym)|uniprotkb:Huntingtin-interacting protein 7(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11531032|imex:IM-24995-910	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012113.1|sgd:S000001415|mint:P40454|dip:DIP-5663N|ensemblfungi:YIL153W(gene)|ensemblfungi:YIL153W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006914"(autophagy)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008160"(protein tyrosine phosphatase activator activity)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0043618"(regulation of transcription from RNA polymerase II promoter in response to stress)|interpro:IPR004327(Phosphotyrosyl phosphatase activator, PTPA)|interpro:IPR037218|interpro:IPR043170|rcsb pdb:2IXO|rcsb pdb:2IXP|sgd:YIL153W(identity)	refseq:NP_001008212.1|refseq:NP_001008213.1|refseq:NP_001008214.1|refseq:NP_068815.2|ensembl:ENSG00000123240(gene)|ensembl:ENST00000263036(transcript)|ensembl:ENST00000378747(transcript)|ensembl:ENST00000378748(transcript)|ensembl:ENST00000378757(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001920"(negative regulation of receptor recycling)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0007030"(Golgi organization)|go:"GO:0007165"(signal transduction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008219"(cell death)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0061734"(parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:1904417"(positive regulation of xenophagy)|interpro:IPR021063|interpro:IPR032419|interpro:IPR032939|interpro:IPR034735|mint:Q96CV9|rcsb pdb:2LO4|rcsb pdb:2LUE|rcsb pdb:3VTV|rcsb pdb:3VTW|rcsb pdb:5AAZ|rcsb pdb:5B83|rcsb pdb:5EOA|rcsb pdb:5EOF|rcsb pdb:7CZM|reactome:R-HSA-2565942|reactome:R-HSA-8854214|dip:DIP-42001N|entrezgene/locuslink:10133(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2018/04/06	rogid:It2q8WlpmvLEZ1fqpRF5Fypw9Q4559292	rogid:jcCTXDx1bJq3K5mgNUD73jeWeBU9606	intact-crc:8DDD4CD467ECFC10|rigid:qhPMcGgyIW6NDLjpoigBcTOf55k	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40454	uniprotkb:Q8TC20-4	intact:EBI-25278|uniprotkb:D6VVD4|ensemblfungi:YIL153W	intact:EBI-11522698|ensembl:ENSP00000390644	psi-mi:ptpa1_yeast(display_long)|uniprotkb:YIL153W(locus name)|uniprotkb:RRD1(gene name)|psi-mi:RRD1(display_short)|uniprotkb:NCS1(gene name synonym)|uniprotkb:YPA1(gene name synonym)|uniprotkb:Peptidyl-prolyl cis-trans isomerase PTPA-1(gene name synonym)|uniprotkb:Phosphotyrosyl phosphatase activator 1(gene name synonym)	psi-mi:q8tc20-4(display_long)|uniprotkb:CTAG3(gene name synonym)|uniprotkb:Cancer/testis antigen 3(gene name synonym)|uniprotkb:CAGE1(gene name)|psi-mi:CAGE1(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11531023|imex:IM-24995-909	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012113.1|sgd:S000001415|mint:P40454|dip:DIP-5663N|ensemblfungi:YIL153W(gene)|ensemblfungi:YIL153W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006914"(autophagy)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008160"(protein tyrosine phosphatase activator activity)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0043618"(regulation of transcription from RNA polymerase II promoter in response to stress)|interpro:IPR004327(Phosphotyrosyl phosphatase activator, PTPA)|interpro:IPR037218|interpro:IPR043170|rcsb pdb:2IXO|rcsb pdb:2IXP|sgd:YIL153W(identity)	intact:EBI-10196469(isoform-parent)|ensembl:ENSG00000164304(gene)|ensembl:ENST00000458291(transcript)|uniprotkb:Q8TC20-4(isoform-parent)|entrezgene/locuslink:285782(identity)	-	-	isoform-comment:No experimental confirmation available. May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:It2q8WlpmvLEZ1fqpRF5Fypw9Q4559292	rogid:rbycl1bawuMuBA8D5NfrekzCADM9606	intact-crc:017228A9903AF991|rigid:13PoisQfPDKOkC2l9hFj6Oh7Dzw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9H257-2	uniprotkb:P40454	intact:EBI-11530605|ensembl:ENSP00000360799	intact:EBI-25278|uniprotkb:D6VVD4|ensemblfungi:YIL153W	psi-mi:q9h257-2(display_long)|uniprotkb:CARD9(gene name)|psi-mi:CARD9(display_short)	psi-mi:ptpa1_yeast(display_long)|uniprotkb:YIL153W(locus name)|uniprotkb:RRD1(gene name)|psi-mi:RRD1(display_short)|uniprotkb:NCS1(gene name synonym)|uniprotkb:YPA1(gene name synonym)|uniprotkb:Peptidyl-prolyl cis-trans isomerase PTPA-1(gene name synonym)|uniprotkb:Phosphotyrosyl phosphatase activator 1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11531077|imex:IM-24995-915	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-751319(isoform-parent)|uniprotkb:Q9H257-2(isoform-parent)|ensembl:ENSG00000187796(gene)|ensembl:ENST00000371734(transcript)|entrezgene/locuslink:64170(identity)	refseq:NP_012113.1|sgd:S000001415|mint:P40454|dip:DIP-5663N|ensemblfungi:YIL153W(gene)|ensemblfungi:YIL153W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006914"(autophagy)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008160"(protein tyrosine phosphatase activator activity)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0043618"(regulation of transcription from RNA polymerase II promoter in response to stress)|interpro:IPR004327(Phosphotyrosyl phosphatase activator, PTPA)|interpro:IPR037218|interpro:IPR043170|rcsb pdb:2IXO|rcsb pdb:2IXP|sgd:YIL153W(identity)	-	isoform-comment:No experimental confirmation available.	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:ZXH7B3K5NAzF1LZaeK50ciH1RTE9606	rogid:It2q8WlpmvLEZ1fqpRF5Fypw9Q4559292	intact-crc:BD574C22CEE898CA|rigid:2z6QF0mbGBZcvk5p+cUtRMrS6YM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40454	uniprotkb:Q9BRK4	intact:EBI-25278|uniprotkb:D6VVD4|ensemblfungi:YIL153W	intact:EBI-741037|ensembl:ENSP00000359240|ensembl:ENSP00000359243|uniprotkb:Q8N3I0|uniprotkb:Q96J79|uniprotkb:Q96JL2|uniprotkb:B1AL14|uniprotkb:D3DR72	psi-mi:ptpa1_yeast(display_long)|uniprotkb:YIL153W(locus name)|uniprotkb:RRD1(gene name)|psi-mi:RRD1(display_short)|uniprotkb:NCS1(gene name synonym)|uniprotkb:YPA1(gene name synonym)|uniprotkb:Peptidyl-prolyl cis-trans isomerase PTPA-1(gene name synonym)|uniprotkb:Phosphotyrosyl phosphatase activator 1(gene name synonym)	psi-mi:lzts2_human(display_long)|uniprotkb:Protein LAPSER1(gene name synonym)|uniprotkb:LZTS2(gene name)|psi-mi:LZTS2(display_short)|uniprotkb:KIAA1813(gene name synonym)|uniprotkb:LAPSER1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11531068|imex:IM-24995-914	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012113.1|sgd:S000001415|mint:P40454|dip:DIP-5663N|ensemblfungi:YIL153W(gene)|ensemblfungi:YIL153W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006914"(autophagy)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008160"(protein tyrosine phosphatase activator activity)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0043618"(regulation of transcription from RNA polymerase II promoter in response to stress)|interpro:IPR004327(Phosphotyrosyl phosphatase activator, PTPA)|interpro:IPR037218|interpro:IPR043170|rcsb pdb:2IXO|rcsb pdb:2IXP|sgd:YIL153W(identity)	refseq:NP_115805.1|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030496"(midbody)|go:"GO:0031982"(vesicle)|go:"GO:0051013"(microtubule severing)|go:"GO:0051168"(nuclear export)|go:"GO:0051255"(spindle midzone assembly)|go:"GO:0060682"(primary ureteric bud growth)|go:"GO:0072197"(ureter morphogenesis)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|interpro:IPR028597|mint:Q9BRK4|ensembl:ENSG00000107816(gene)|ensembl:ENST00000370220(transcript)|ensembl:ENST00000370223(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0008285"(negative regulation of cell population proliferation)|refseq:XP_016872269.1|refseq:NP_001305028.1|refseq:NP_001305029.1|refseq:NP_001305030.1|refseq:XP_005270279.1|entrezgene/locuslink:84445(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:It2q8WlpmvLEZ1fqpRF5Fypw9Q4559292	rogid:OaMJmnmfm6JniKUJeyg7fS6zRcw9606	intact-crc:8A8DBC0CA7695775|rigid:vNww3lkR6EPnywLIB41ksn2lzxs	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96MT8-3	uniprotkb:P40454	intact:EBI-11522539|ensembl:ENSP00000507703|ensembl:ENSP00000328382|ensembl:ENSP00000506728|ensembl:ENSP00000506791|ensembl:ENSP00000506828|ensembl:ENSP00000507228	intact:EBI-25278|uniprotkb:D6VVD4|ensemblfungi:YIL153W	psi-mi:q96mt8-3(display_long)|uniprotkb:CEP63(gene name)|psi-mi:CEP63(display_short)	psi-mi:ptpa1_yeast(display_long)|uniprotkb:YIL153W(locus name)|uniprotkb:RRD1(gene name)|psi-mi:RRD1(display_short)|uniprotkb:NCS1(gene name synonym)|uniprotkb:YPA1(gene name synonym)|uniprotkb:Peptidyl-prolyl cis-trans isomerase PTPA-1(gene name synonym)|uniprotkb:Phosphotyrosyl phosphatase activator 1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11531059|imex:IM-24995-913	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-741977(isoform-parent)|ensembl:ENST00000332047(transcript)|ensembl:ENST00000682042(transcript)|ensembl:ENST00000682800(transcript)|ensembl:ENST00000682858(transcript)|ensembl:ENST00000683177(transcript)|ensembl:ENST00000683861(transcript)|ensembl:ENSG00000182923(gene)|uniprotkb:Q96MT8-3(isoform-parent)|entrezgene/locuslink:80254(identity)	refseq:NP_012113.1|sgd:S000001415|mint:P40454|dip:DIP-5663N|ensemblfungi:YIL153W(gene)|ensemblfungi:YIL153W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006914"(autophagy)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008160"(protein tyrosine phosphatase activator activity)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0043618"(regulation of transcription from RNA polymerase II promoter in response to stress)|interpro:IPR004327(Phosphotyrosyl phosphatase activator, PTPA)|interpro:IPR037218|interpro:IPR043170|rcsb pdb:2IXO|rcsb pdb:2IXP|sgd:YIL153W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:U0uvVcOCzA8Qp2cCB0ilixgd4Yc9606	rogid:It2q8WlpmvLEZ1fqpRF5Fypw9Q4559292	intact-crc:1D7EEB3E15215284|rigid:Ql13sIEA35Z0th8Tdvq89H0re2s	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96GX9	uniprotkb:P40454	intact:EBI-359248|ensembl:ENSP00000379133|intact:EBI-2848621|uniprotkb:Q6PJX6|uniprotkb:Q8WVU2|uniprotkb:Q96HK2|uniprotkb:Q9Y318|uniprotkb:A8K9D3	intact:EBI-25278|uniprotkb:D6VVD4|ensemblfungi:YIL153W	psi-mi:mtnb_human(display_long)|uniprotkb:APIP(gene name)|psi-mi:APIP(display_short)|uniprotkb:CGI-29(orf name)|uniprotkb:APAF1-interacting protein(gene name synonym)	psi-mi:ptpa1_yeast(display_long)|uniprotkb:YIL153W(locus name)|uniprotkb:RRD1(gene name)|psi-mi:RRD1(display_short)|uniprotkb:NCS1(gene name synonym)|uniprotkb:YPA1(gene name synonym)|uniprotkb:Peptidyl-prolyl cis-trans isomerase PTPA-1(gene name synonym)|uniprotkb:Phosphotyrosyl phosphatase activator 1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11531050|imex:IM-24995-912	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000149089(gene)|ensembl:ENST00000395787(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019284"(L-methionine salvage from S-adenosylmethionine)|go:"GO:0019509"(L-methionine salvage from methylthioadenosine)|refseq:NP_057041.2|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0046570"(methylthioribulose 1-phosphate dehydratase activity)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0070269"(pyroptosis)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|interpro:IPR001303(Class II aldolase/adducin, N-terminal)|interpro:IPR017714(Methylthioribulose-1-phosphate dehydratase)|interpro:IPR027514|interpro:IPR036409|rcsb pdb:4M6R|reactome:R-HSA-111458|reactome:R-HSA-1237112|reactome:R-HSA-9627069|entrezgene/locuslink:51074(identity)	refseq:NP_012113.1|sgd:S000001415|mint:P40454|dip:DIP-5663N|ensemblfungi:YIL153W(gene)|ensemblfungi:YIL153W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006914"(autophagy)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008160"(protein tyrosine phosphatase activator activity)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0043618"(regulation of transcription from RNA polymerase II promoter in response to stress)|interpro:IPR004327(Phosphotyrosyl phosphatase activator, PTPA)|interpro:IPR037218|interpro:IPR043170|rcsb pdb:2IXO|rcsb pdb:2IXP|sgd:YIL153W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:k+IcLEB6jPgZW0Zl597PZyGbHH49606	rogid:It2q8WlpmvLEZ1fqpRF5Fypw9Q4559292	intact-crc:06FCDABAE23898A9|rigid:HYMUYXyFDqqwnxfs/MAmVdVHFVU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UI14	uniprotkb:P40454	intact:EBI-712367|ensembl:ENSP00000222008|uniprotkb:Q7Z4Y2|uniprotkb:Q9Y3R1	intact:EBI-25278|uniprotkb:D6VVD4|ensemblfungi:YIL153W	psi-mi:praf1_human(display_long)|uniprotkb:PRA1 family protein 1(gene name synonym)|uniprotkb:RABAC1(gene name)|psi-mi:RABAC1(display_short)|uniprotkb:PRA1(gene name synonym)|uniprotkb:PRAF1(gene name synonym)	psi-mi:ptpa1_yeast(display_long)|uniprotkb:YIL153W(locus name)|uniprotkb:RRD1(gene name)|psi-mi:RRD1(display_short)|uniprotkb:NCS1(gene name synonym)|uniprotkb:YPA1(gene name synonym)|uniprotkb:Peptidyl-prolyl cis-trans isomerase PTPA-1(gene name synonym)|uniprotkb:Phosphotyrosyl phosphatase activator 1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11531095|imex:IM-24995-917	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006414.2|ensembl:ENSG00000105404(gene)|ensembl:ENST00000222008(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0070064"(proline-rich region binding)|interpro:IPR004895(Prenylated rab acceptor PRA1)|mint:Q9UI14|entrezgene/locuslink:10567(identity)	refseq:NP_012113.1|sgd:S000001415|mint:P40454|dip:DIP-5663N|ensemblfungi:YIL153W(gene)|ensemblfungi:YIL153W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006914"(autophagy)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008160"(protein tyrosine phosphatase activator activity)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0043618"(regulation of transcription from RNA polymerase II promoter in response to stress)|interpro:IPR004327(Phosphotyrosyl phosphatase activator, PTPA)|interpro:IPR037218|interpro:IPR043170|rcsb pdb:2IXO|rcsb pdb:2IXP|sgd:YIL153W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:WS2rUY7yXRbR7pqWgfUCbnEiDbg9606	rogid:It2q8WlpmvLEZ1fqpRF5Fypw9Q4559292	intact-crc:CBFE111A363ABD82|rigid:AUXe+NvVLCGB7t8ALTMh9ZY60R4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40454	uniprotkb:Q9NR46	intact:EBI-25278|uniprotkb:D6VVD4|ensemblfungi:YIL153W	intact:EBI-749607|uniprotkb:A8MPS4|uniprotkb:Q8WY61|uniprotkb:Q96JH9|uniprotkb:A6NC47|ensembl:ENSP00000361640|ensembl:ENSP00000361645	psi-mi:ptpa1_yeast(display_long)|uniprotkb:YIL153W(locus name)|uniprotkb:RRD1(gene name)|psi-mi:RRD1(display_short)|uniprotkb:NCS1(gene name synonym)|uniprotkb:YPA1(gene name synonym)|uniprotkb:Peptidyl-prolyl cis-trans isomerase PTPA-1(gene name synonym)|uniprotkb:Phosphotyrosyl phosphatase activator 1(gene name synonym)	psi-mi:shlb2_human(display_long)|uniprotkb:SH3 domain-containing GRB2-like protein B2(gene name synonym)|uniprotkb:SH3GLB2(gene name)|psi-mi:SH3GLB2(display_short)|uniprotkb:KIAA1848(gene name synonym)|uniprotkb:PP578(orf name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11531086|imex:IM-24995-916	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012113.1|sgd:S000001415|mint:P40454|dip:DIP-5663N|ensemblfungi:YIL153W(gene)|ensemblfungi:YIL153W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006914"(autophagy)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008160"(protein tyrosine phosphatase activator activity)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0043618"(regulation of transcription from RNA polymerase II promoter in response to stress)|interpro:IPR004327(Phosphotyrosyl phosphatase activator, PTPA)|interpro:IPR037218|interpro:IPR043170|rcsb pdb:2IXO|rcsb pdb:2IXP|sgd:YIL153W(identity)	refseq:NP_064530.1|refseq:NP_001273974.1|refseq:NP_001273975.1|refseq:XP_005252158.1|ensembl:ENSG00000148341(gene)|ensembl:ENST00000372559(transcript)|ensembl:ENST00000372564(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|interpro:IPR001452(Src homology-3)|interpro:IPR004148(BAR)|interpro:IPR027267|interpro:IPR035640|interpro:IPR036028|mint:Q9NR46|entrezgene/locuslink:56904(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:It2q8WlpmvLEZ1fqpRF5Fypw9Q4559292	rogid:9C0QF9xLb5A6eYQBK2aU/J1aGVo9606	intact-crc:C5C8BB327B8C6208|rigid:HyVSTToe8JVRRQ/VlG5SkOii4/4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UJV3-2	uniprotkb:P40454	intact:EBI-10172526|ensembl:ENSP00000413976	intact:EBI-25278|uniprotkb:D6VVD4|ensemblfungi:YIL153W	psi-mi:q9ujv3-2(display_long)|uniprotkb:RING-type E3 ubiquitin transferase MID2(gene name synonym)|uniprotkb:FXY2(gene name synonym)|uniprotkb:Midin-2(gene name synonym)|uniprotkb:Midline defect 2(gene name synonym)|uniprotkb:Midline-2(gene name synonym)|uniprotkb:RING finger protein 60(gene name synonym)|uniprotkb:RNF60(gene name synonym)|uniprotkb:TRIM1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 1(gene name synonym)|uniprotkb:MID2(gene name)|psi-mi:MID2(display_short)	psi-mi:ptpa1_yeast(display_long)|uniprotkb:YIL153W(locus name)|uniprotkb:RRD1(gene name)|psi-mi:RRD1(display_short)|uniprotkb:NCS1(gene name synonym)|uniprotkb:YPA1(gene name synonym)|uniprotkb:Peptidyl-prolyl cis-trans isomerase PTPA-1(gene name synonym)|uniprotkb:Phosphotyrosyl phosphatase activator 1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11531104|imex:IM-24995-918	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-751983(isoform-parent)|uniprotkb:Q9UJV3-2(isoform-parent)|ensembl:ENSG00000080561(gene)|ensembl:ENST00000443968(transcript)|entrezgene/locuslink:11043(identity)	refseq:NP_012113.1|sgd:S000001415|mint:P40454|dip:DIP-5663N|ensemblfungi:YIL153W(gene)|ensemblfungi:YIL153W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006914"(autophagy)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008160"(protein tyrosine phosphatase activator activity)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0043618"(regulation of transcription from RNA polymerase II promoter in response to stress)|interpro:IPR004327(Phosphotyrosyl phosphatase activator, PTPA)|interpro:IPR037218|interpro:IPR043170|rcsb pdb:2IXO|rcsb pdb:2IXP|sgd:YIL153W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:/FJ+V2H7SaWon7caUWkEkmHFVxQ9606	rogid:It2q8WlpmvLEZ1fqpRF5Fypw9Q4559292	intact-crc:31FB404665EF7C12|rigid:CcpVbbc0xfEqFA2I3Oq4E/m04K8	false	sufficient binding region:21-705	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40454	uniprotkb:Q9Y3Q8	intact:EBI-25278|uniprotkb:D6VVD4|ensemblfungi:YIL153W	intact:EBI-739485|uniprotkb:A8MWR6|ensembl:ENSP00000300181|uniprotkb:A4D2C3|uniprotkb:D6W5V9	psi-mi:ptpa1_yeast(display_long)|uniprotkb:YIL153W(locus name)|uniprotkb:RRD1(gene name)|psi-mi:RRD1(display_short)|uniprotkb:NCS1(gene name synonym)|uniprotkb:YPA1(gene name synonym)|uniprotkb:Peptidyl-prolyl cis-trans isomerase PTPA-1(gene name synonym)|uniprotkb:Phosphotyrosyl phosphatase activator 1(gene name synonym)	psi-mi:t22d4_human(display_long)|uniprotkb:TSC22D4(gene name)|psi-mi:TSC22D4(display_short)|uniprotkb:TILZ2(gene name synonym)|uniprotkb:TSC22-related-inducible leucine zipper protein 2(gene name synonym)|uniprotkb:Tsc-22-like protein THG-1(gene name synonym)|uniprotkb:THG1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11531135|imex:IM-24995-921	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012113.1|sgd:S000001415|mint:P40454|dip:DIP-5663N|ensemblfungi:YIL153W(gene)|ensemblfungi:YIL153W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006914"(autophagy)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008160"(protein tyrosine phosphatase activator activity)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0043618"(regulation of transcription from RNA polymerase II promoter in response to stress)|interpro:IPR004327(Phosphotyrosyl phosphatase activator, PTPA)|interpro:IPR037218|interpro:IPR043170|rcsb pdb:2IXO|rcsb pdb:2IXP|sgd:YIL153W(identity)	ensembl:ENSG00000166925(gene)|ensembl:ENST00000300181(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006970"(response to osmotic stress)|interpro:IPR000580(TSC-22 / Dip / Bun)|interpro:IPR042553|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|refseq:NP_112197.1|refseq:NP_001289972.1|entrezgene/locuslink:81628(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:It2q8WlpmvLEZ1fqpRF5Fypw9Q4559292	rogid:eL12cHY76zEPOXzT1HFKPSckS8Y9606	intact-crc:C3DDF019B404DAFF|rigid:Z3ZOSQgaqcMkkGs4LrBuRiUQYSc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40454	uniprotkb:Q9Y3A3	intact:EBI-25278|uniprotkb:D6VVD4|ensemblfungi:YIL153W	intact:EBI-713935|uniprotkb:Q7Z4Y6|uniprotkb:Q9H2P3|uniprotkb:Q53SE0|uniprotkb:Q9H5J1|uniprotkb:Q9Y4T8|ensembl:ENSP00000315702|uniprotkb:B4DML0	psi-mi:ptpa1_yeast(display_long)|uniprotkb:YIL153W(locus name)|uniprotkb:RRD1(gene name)|psi-mi:RRD1(display_short)|uniprotkb:NCS1(gene name synonym)|uniprotkb:YPA1(gene name synonym)|uniprotkb:Peptidyl-prolyl cis-trans isomerase PTPA-1(gene name synonym)|uniprotkb:Phosphotyrosyl phosphatase activator 1(gene name synonym)	psi-mi:phocn_human(display_long)|uniprotkb:MOB4(gene name)|psi-mi:MOB4(display_short)|uniprotkb:2C4D(gene name synonym)|uniprotkb:Class II mMOB1(gene name synonym)|uniprotkb:MOB3(gene name synonym)|uniprotkb:MOBKL3(gene name synonym)|uniprotkb:Mob1 homolog 3(gene name synonym)|uniprotkb:Mps one binder kinase activator-like 3(gene name synonym)|uniprotkb:PHOCN(gene name synonym)|uniprotkb:PREI3(gene name synonym)|uniprotkb:Preimplantation protein 3(gene name synonym)|uniprotkb:CGI-95(orf name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11531126|imex:IM-24995-920	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012113.1|sgd:S000001415|mint:P40454|dip:DIP-5663N|ensemblfungi:YIL153W(gene)|ensemblfungi:YIL153W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006914"(autophagy)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008160"(protein tyrosine phosphatase activator activity)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0043618"(regulation of transcription from RNA polymerase II promoter in response to stress)|interpro:IPR004327(Phosphotyrosyl phosphatase activator, PTPA)|interpro:IPR037218|interpro:IPR043170|rcsb pdb:2IXO|rcsb pdb:2IXP|sgd:YIL153W(identity)	ensembl:ENSG00000115540(gene)|ensembl:ENST00000323303(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR005301(Mob1/phocein)|interpro:IPR036703|mint:Q9Y3A3|rcsb pdb:5YF4|rcsb pdb:7K36|refseq:NP_001094289.1|refseq:NP_001191023.1|refseq:NP_056202.2|refseq:NP_955776.1|entrezgene/locuslink:25843(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:It2q8WlpmvLEZ1fqpRF5Fypw9Q4559292	rogid:ihsb3qrdGqwKdh6ZhHlJlwBGJbc9606	intact-crc:BB9884640ACC7BA4|rigid:Cbagm22pvT6WWsyDkpFx9yTzWz4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40454	uniprotkb:Q9Y2J4	intact:EBI-25278|uniprotkb:D6VVD4|ensemblfungi:YIL153W	intact:EBI-746752|intact:EBI-28986657|ensembl:ENSP00000409999|uniprotkb:Q53EP1|uniprotkb:Q96F99|uniprotkb:Q9UKB4|uniprotkb:A8K6F1|uniprotkb:B7Z5Q1|uniprotkb:E9PHW3	psi-mi:ptpa1_yeast(display_long)|uniprotkb:YIL153W(locus name)|uniprotkb:RRD1(gene name)|psi-mi:RRD1(display_short)|uniprotkb:NCS1(gene name synonym)|uniprotkb:YPA1(gene name synonym)|uniprotkb:Peptidyl-prolyl cis-trans isomerase PTPA-1(gene name synonym)|uniprotkb:Phosphotyrosyl phosphatase activator 1(gene name synonym)	psi-mi:amol2_human(display_long)|uniprotkb:Leman coiled-coil protein(gene name synonym)|uniprotkb:AMOTL2(gene name)|psi-mi:AMOTL2(display_short)|uniprotkb:KIAA0989(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11531115|imex:IM-24995-919	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012113.1|sgd:S000001415|mint:P40454|dip:DIP-5663N|ensemblfungi:YIL153W(gene)|ensemblfungi:YIL153W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006914"(autophagy)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008160"(protein tyrosine phosphatase activator activity)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0043618"(regulation of transcription from RNA polymerase II promoter in response to stress)|interpro:IPR004327(Phosphotyrosyl phosphatase activator, PTPA)|interpro:IPR037218|interpro:IPR043170|rcsb pdb:2IXO|rcsb pdb:2IXP|sgd:YIL153W(identity)	refseq:NP_001265612.1|refseq:NP_001265614.1|ensembl:ENSG00000114019(gene)|refseq:XP_006713717.1|refseq:NP_057285.3|refseq:XP_011511183.1|ensembl:ENST00000422605(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0003365"(establishment of cell polarity involved in ameboidal cell migration)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0035329"(hippo signaling)|go:"GO:0055037"(recycling endosome)|interpro:IPR009114(Angiomotin)|interpro:IPR024646|mint:Q9Y2J4|reactome:R-HSA-2028269|refseq:XP_016862069.1|refseq:XP_016862070.1|refseq:XP_016862071.1|ensembl:ENST00000249883|ensembl:ENSP00000249883|ensembl:ENSP00000409999|ensembl:ENST00000513145|ensembl:ENSP00000425475|ensembl:ENST00000514516|ensembl:ENSP00000424765|dip:DIP-57510N|entrezgene/locuslink:51421(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:It2q8WlpmvLEZ1fqpRF5Fypw9Q4559292	rogid:SHtKAcLLnTpSSLwVE7yQ1WECoZk9606	intact-crc:228917BBEE4A8139|rigid:rgEEfEcCVSwx03CIHbOgbMIWwIs	false	-	sufficient binding region:314-779	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8N9N5-2	uniprotkb:P40455	intact:EBI-11524452|ensembl:ENSP00000347125	intact:EBI-25274|uniprotkb:D6VVD5|ensemblfungi:YIL152W	psi-mi:q8n9n5-2(display_long)|uniprotkb:BANP(gene name)|psi-mi:BANP(display_short)|uniprotkb:BEN domain-containing protein 1(gene name synonym)|uniprotkb:BEND1(gene name synonym)|uniprotkb:Btg3-associated nuclear protein(gene name synonym)|uniprotkb:SMAR1(gene name synonym)|uniprotkb:Scaffold/matrix-associated region-1-binding protein(gene name synonym)	psi-mi:yip2_yeast(display_long)|uniprotkb:YIL152W(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11531173|imex:IM-24995-925	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000172530(gene)|ensembl:ENST00000355022(transcript)|intact:EBI-744695(isoform-parent)|uniprotkb:Q8N9N5-2(isoform-parent)|entrezgene/locuslink:54971(identity)	sgd:S000001414|refseq:NP_012114.1|mint:P40455|dip:DIP-2047N|ensemblfungi:YIL152W(gene)|ensemblfungi:YIL152W_mRNA(transcript)|sgd:YIL152W(identity)	-	-	crc64:07550E3F491F53A8	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:ESe6iCAhvq+i57fQHz3rGyg6UOo9606	rogid:t5hCm1ck6kpFUxpEd8CsyLrHbEw559292	intact-crc:8F443BB288FC84E0|rigid:Y6m8Umk009Rd1Pv4uhcYS7loBOg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q5JR59-3	uniprotkb:P40455	intact:EBI-11522433|ensembl:ENSP00000370186	intact:EBI-25274|uniprotkb:D6VVD5|ensemblfungi:YIL152W	psi-mi:q5jr59-3(display_long)|uniprotkb:MTUS2(gene name)|psi-mi:MTUS2(display_short)|uniprotkb:CAZIP(gene name synonym)|uniprotkb:Cardiac zipper protein(gene name synonym)|uniprotkb:KIAA0774(gene name synonym)|uniprotkb:Microtubule plus-end tracking protein TIP150(gene name synonym)|uniprotkb:TIP150(gene name synonym)	psi-mi:yip2_yeast(display_long)|uniprotkb:YIL152W(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11531164|imex:IM-24995-924	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000132938(gene)|ensembl:ENST00000380808(transcript)|intact:EBI-742948(isoform-parent)|uniprotkb:Q5JR59-3(isoform-parent)|entrezgene/locuslink:23281(identity)	sgd:S000001414|refseq:NP_012114.1|mint:P40455|dip:DIP-2047N|ensemblfungi:YIL152W(gene)|ensemblfungi:YIL152W_mRNA(transcript)|sgd:YIL152W(identity)	-	isoform-comment:No experimental confirmation available.	crc64:07550E3F491F53A8	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:npId9tC7VoLN/jteoBiRbSYChPs9606	rogid:t5hCm1ck6kpFUxpEd8CsyLrHbEw559292	intact-crc:7603E93A4EB0C363|rigid:rDuZDZJuGb65exhgQM2kW3j5YMI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O14641	uniprotkb:P40455	intact:EBI-740850|ensembl:ENSP00000005340|uniprotkb:Q53XM0|uniprotkb:D3DTN3	intact:EBI-25274|uniprotkb:D6VVD5|ensemblfungi:YIL152W	psi-mi:dvl2_human(display_long)|uniprotkb:DSH homolog 2(gene name synonym)|uniprotkb:DVL2(gene name)|psi-mi:DVL2(display_short)	psi-mi:yip2_yeast(display_long)|uniprotkb:YIL152W(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11531155|imex:IM-24995-923	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004413.1|ensembl:ENSG00000004975(gene)|ensembl:ENST00000005340(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005109"(frizzled binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0007507"(heart development)|go:"GO:0016235"(aggresome)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044340"(canonical Wnt signaling pathway involved in regulation of cell proliferation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0150012"(positive regulation of neuron projection arborization)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008341(Dishevelled-2 region)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:O14641|rcsb pdb:2REY|rcsb pdb:3CBX|rcsb pdb:3CBY|rcsb pdb:3CBZ|rcsb pdb:3CC0|rcsb pdb:4WIP|rcsb pdb:5LNP|rcsb pdb:5SUY|rcsb pdb:5SUZ|rcsb pdb:6IW3|rcsb pdb:6JCK|reactome:R-HSA-201681|reactome:R-HSA-201688|reactome:R-HSA-2028269|reactome:R-HSA-4086400|reactome:R-HSA-4608870|reactome:R-HSA-4641258|reactome:R-HSA-4641262|reactome:R-HSA-5099900|reactome:R-HSA-5368598|reactome:R-HSA-5663220|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9673324|ensembl:ENSP00000005340|dip:DIP-34433N|entrezgene/locuslink:1856(identity)	sgd:S000001414|refseq:NP_012114.1|mint:P40455|dip:DIP-2047N|ensemblfungi:YIL152W(gene)|ensemblfungi:YIL152W_mRNA(transcript)|sgd:YIL152W(identity)	-	-	crc64:07550E3F491F53A8	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:2Vdc8oRnT4Mz/j+EXQXrL3AszOc9606	rogid:t5hCm1ck6kpFUxpEd8CsyLrHbEw559292	intact-crc:4EA22CA6D7D21069|rigid:6KNcHMZ71nkyff8OYwPyQlhJ8vA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q08379	uniprotkb:P40455	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	intact:EBI-25274|uniprotkb:D6VVD5|ensemblfungi:YIL152W	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:yip2_yeast(display_long)|uniprotkb:YIL152W(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11531144|imex:IM-24995-922	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N|entrezgene/locuslink:2801(identity)	sgd:S000001414|refseq:NP_012114.1|mint:P40455|dip:DIP-2047N|ensemblfungi:YIL152W(gene)|ensemblfungi:YIL152W_mRNA(transcript)|sgd:YIL152W(identity)	-	-	crc64:07550E3F491F53A8	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2017/05/26	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	rogid:t5hCm1ck6kpFUxpEd8CsyLrHbEw559292	intact-crc:C65E8FF882C3C4A1|rigid:X+W6oH3jCPQgWHpfShH+ReGKEHU	false	sufficient binding region:383-1002	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40460	uniprotkb:O14964	intact:EBI-25247|uniprotkb:D6VVE3|ensemblfungi:YIL144W	intact:EBI-740220|uniprotkb:Q9NR36|ensembl:ENSP00000331201|ensembl:ENSP00000504106	psi-mi:ndc80_yeast(display_long)|uniprotkb:NDC80(gene name)|psi-mi:NDC80(display_short)|uniprotkb:80 kDa spindle component protein(gene name synonym)|uniprotkb:HEC1(gene name synonym)|uniprotkb:Nuclear division cycle protein 80(gene name synonym)|uniprotkb:TID3(gene name synonym)|uniprotkb:Two-hybrid interaction with DMC1 protein 3(gene name synonym)|uniprotkb:YIL144W(locus name)	psi-mi:hgs_human(display_long)|uniprotkb:Protein pp110(gene name synonym)|uniprotkb:Hrs(gene name synonym)|uniprotkb:HGS(gene name)|psi-mi:HGS(display_short)|uniprotkb:HRS(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11531200|imex:IM-24995-928	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000001406|refseq:NP_012122.3|mint:P40460|dip:DIP-818N|ensemblfungi:YIL144W(gene)|ensemblfungi:YIL144W_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0007059"(chromosome segregation)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0042802"(identical protein binding)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|interpro:IPR005550(HEC/Ndc80p)|interpro:IPR038273|interpro:IPR040967|rcsb pdb:5TCS|rcsb pdb:5TD8|rcsb pdb:7KDF|sgd:YIL144W(identity)	refseq:NP_004703.1|dip:DIP-29050N|ensembl:ENSG00000185359(gene)|ensembl:ENST00000329138(transcript)|ensembl:ENST00000676546(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0007165"(signal transduction)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010324"(membrane invagination)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010642"(negative regulation of platelet-derived growth factor receptor signaling pathway)|go:"GO:0016197"(endosomal transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032585"(multivesicular body membrane)|go:"GO:0033565"(ESCRT-0 complex)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043405"(regulation of MAP kinase activity)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072657"(protein localization to membrane)|go:"GO:0097013"(phagocytic vesicle lumen)|go:"GO:1903543"(positive regulation of exosomal secretion)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR002014(VHS)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017073(Ubiquitin binding protein, Hrs/VPS27)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR024641|mint:O14964|rcsb pdb:2D3G|rcsb pdb:3F1I|rcsb pdb:3OBQ|rcsb pdb:3ZYQ|rcsb pdb:4AVX|reactome:R-HSA-182971|reactome:R-HSA-432720|reactome:R-HSA-5689880|reactome:R-HSA-6807004|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8875360|reactome:R-HSA-9013420|reactome:R-HSA-917729|reactome:R-HSA-9635644|reactome:R-HSA-9636383|reactome:R-HSA-9706019|entrezgene/locuslink:9146(identity)	-	crc64:7DBC492227A80093	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:ZrT7N4pBKz6upSglhGhOqgeoAYw559292	rogid:z/AnREuqEpyJ9/Zj6JFCJCJem1I9606	intact-crc:94083552AABD0E34|rigid:q6e4XfVFovWkoLeZrXGfwCTLUAU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9Y3Q8	uniprotkb:P40455	intact:EBI-739485|uniprotkb:A8MWR6|ensembl:ENSP00000300181|uniprotkb:A4D2C3|uniprotkb:D6W5V9	intact:EBI-25274|uniprotkb:D6VVD5|ensemblfungi:YIL152W	psi-mi:t22d4_human(display_long)|uniprotkb:TSC22D4(gene name)|psi-mi:TSC22D4(display_short)|uniprotkb:TILZ2(gene name synonym)|uniprotkb:TSC22-related-inducible leucine zipper protein 2(gene name synonym)|uniprotkb:Tsc-22-like protein THG-1(gene name synonym)|uniprotkb:THG1(gene name synonym)	psi-mi:yip2_yeast(display_long)|uniprotkb:YIL152W(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11531191|imex:IM-24995-927	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000166925(gene)|ensembl:ENST00000300181(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006970"(response to osmotic stress)|interpro:IPR000580(TSC-22 / Dip / Bun)|interpro:IPR042553|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|refseq:NP_112197.1|refseq:NP_001289972.1|entrezgene/locuslink:81628(identity)	sgd:S000001414|refseq:NP_012114.1|mint:P40455|dip:DIP-2047N|ensemblfungi:YIL152W(gene)|ensemblfungi:YIL152W_mRNA(transcript)|sgd:YIL152W(identity)	-	-	crc64:07550E3F491F53A8	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:eL12cHY76zEPOXzT1HFKPSckS8Y9606	rogid:t5hCm1ck6kpFUxpEd8CsyLrHbEw559292	intact-crc:D460A76B6C5A4F2C|rigid:PGN/CnxnWOmURFFkj+OFUHbLKt4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40455	uniprotkb:Q9BRK4	intact:EBI-25274|uniprotkb:D6VVD5|ensemblfungi:YIL152W	intact:EBI-741037|ensembl:ENSP00000359240|ensembl:ENSP00000359243|uniprotkb:Q8N3I0|uniprotkb:Q96J79|uniprotkb:Q96JL2|uniprotkb:B1AL14|uniprotkb:D3DR72	psi-mi:yip2_yeast(display_long)|uniprotkb:YIL152W(locus name)	psi-mi:lzts2_human(display_long)|uniprotkb:Protein LAPSER1(gene name synonym)|uniprotkb:LZTS2(gene name)|psi-mi:LZTS2(display_short)|uniprotkb:KIAA1813(gene name synonym)|uniprotkb:LAPSER1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11531182|imex:IM-24995-926	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000001414|refseq:NP_012114.1|mint:P40455|dip:DIP-2047N|ensemblfungi:YIL152W(gene)|ensemblfungi:YIL152W_mRNA(transcript)|sgd:YIL152W(identity)	refseq:NP_115805.1|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030496"(midbody)|go:"GO:0031982"(vesicle)|go:"GO:0051013"(microtubule severing)|go:"GO:0051168"(nuclear export)|go:"GO:0051255"(spindle midzone assembly)|go:"GO:0060682"(primary ureteric bud growth)|go:"GO:0072197"(ureter morphogenesis)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|interpro:IPR028597|mint:Q9BRK4|ensembl:ENSG00000107816(gene)|ensembl:ENST00000370220(transcript)|ensembl:ENST00000370223(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0008285"(negative regulation of cell population proliferation)|refseq:XP_016872269.1|refseq:NP_001305028.1|refseq:NP_001305029.1|refseq:NP_001305030.1|refseq:XP_005270279.1|entrezgene/locuslink:84445(identity)	-	crc64:07550E3F491F53A8	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:t5hCm1ck6kpFUxpEd8CsyLrHbEw559292	rogid:OaMJmnmfm6JniKUJeyg7fS6zRcw9606	intact-crc:881E60206CC5CFDE|rigid:GoCOO6g/qfkgYjYzvQ4SGVZo+/Y	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q93062-3	uniprotkb:P40473	intact:EBI-740343|ensembl:ENSP00000340176	intact:EBI-25207|uniprotkb:D6VVG5|ensemblfungi:YIL122W	psi-mi:q93062-3(display_long)|uniprotkb:RBPMS(gene name)|psi-mi:RBPMS(display_short)|uniprotkb:HERMES(gene name synonym)|uniprotkb:Heart and RRM expressed sequence(gene name synonym)	psi-mi:pog1_yeast(display_long)|uniprotkb:YIL122W(locus name)|uniprotkb:POG1(gene name)|psi-mi:POG1(display_short)|uniprotkb:Promoter of growth protein 1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11531238|imex:IM-24995-932	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-740322(rbpms_human)|uniprotkb:Q93062-3(isoform-parent)|ensembl:ENSG00000157110(gene)|ensembl:ENST00000339877(transcript)|entrezgene/locuslink:11030(identity)	sgd:S000001384|refseq:NP_012144.1|dip:DIP-2755N|ensemblfungi:YIL122W(gene)|ensemblfungi:YIL122W_mRNA(transcript)|go:"GO:0000321"(re-entry into mitotic cell cycle after pheromone arrest)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051301"(cell division)|sgd:YIL122W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:nlPMQAJoKEbPYBwsL3xodmCKd7c9606	rogid:SL7E0QbXBSeu+JDSQhp7p5rNb8M559292	intact-crc:8F388014CF881514|rigid:LTfvaqT0gfP+tA02L0anJ8XFQLM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40473	uniprotkb:Q6P1W5	intact:EBI-25207|uniprotkb:D6VVG5|ensemblfungi:YIL122W	intact:EBI-946029|uniprotkb:B3KVT1|uniprotkb:Q96IC8|ensembl:ENSP00000435634|uniprotkb:D3DPR3|uniprotkb:E9PJ76	psi-mi:pog1_yeast(display_long)|uniprotkb:YIL122W(locus name)|uniprotkb:POG1(gene name)|psi-mi:POG1(display_short)|uniprotkb:Promoter of growth protein 1(gene name synonym)	psi-mi:ca094_human(display_long)|uniprotkb:C1orf94(gene name)|psi-mi:C1orf94(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11531227|imex:IM-24995-931	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000001384|refseq:NP_012144.1|dip:DIP-2755N|ensemblfungi:YIL122W(gene)|ensemblfungi:YIL122W_mRNA(transcript)|go:"GO:0000321"(re-entry into mitotic cell cycle after pheromone arrest)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051301"(cell division)|sgd:YIL122W(identity)	refseq:NP_001128206.1|refseq:NP_116273.2|ensembl:ENSG00000142698(gene)|ensembl:ENST00000488417(transcript)|interpro:IPR031496|entrezgene/locuslink:84970(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:SL7E0QbXBSeu+JDSQhp7p5rNb8M559292	rogid:y1o4xWvTl2CBA1J7jsP7y8ZjLzM9606	intact-crc:963E74B80240B8E7|rigid:sNt+ZNXzPZW48djk2nYkVKMe1kc	false	-	sufficient binding region:191-598	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P63279	uniprotkb:P40473	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	intact:EBI-25207|uniprotkb:D6VVG5|ensemblfungi:YIL122W	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:pog1_yeast(display_long)|uniprotkb:YIL122W(locus name)|uniprotkb:POG1(gene name)|psi-mi:POG1(display_short)|uniprotkb:Promoter of growth protein 1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11531218|imex:IM-24995-930	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N|entrezgene/locuslink:7329(identity)	sgd:S000001384|refseq:NP_012144.1|dip:DIP-2755N|ensemblfungi:YIL122W(gene)|ensemblfungi:YIL122W_mRNA(transcript)|go:"GO:0000321"(re-entry into mitotic cell cycle after pheromone arrest)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051301"(cell division)|sgd:YIL122W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	rogid:SL7E0QbXBSeu+JDSQhp7p5rNb8M559292	intact-crc:4E07234DE741BA1F|rigid:ex6IWOlG9aqouyaWAdEOM1N7cHs	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96BA8	uniprotkb:P40471	intact:EBI-6942903|ensembl:ENSP00000481956|intact:MINT-268046|intact:MINT-8162577|uniprotkb:Q8N2D5|uniprotkb:Q96CP0	intact:EBI-25213|uniprotkb:D6VVG3|ensemblfungi:YIL124W	psi-mi:cr3l1_human(display_long)|uniprotkb:CREB3L1(gene name)|psi-mi:CREB3L1(display_short)|uniprotkb:OASIS(gene name synonym)|uniprotkb:PSEC0238(orf name)|uniprotkb:Old astrocyte specifically-induced substance(gene name synonym)	psi-mi:ayr1_yeast(display_long)|uniprotkb:AYR1(gene name)|psi-mi:AYR1(display_short)|uniprotkb:Acylglycerone-phosphate reductase(gene name synonym)|uniprotkb:1-acyl DHAP reductase(gene name synonym)|uniprotkb:Acyl/alkyl DHAP reductase(gene name synonym)|uniprotkb:GBG1(gene name synonym)|uniprotkb:Triacylglycerol lipase AYR1(gene name synonym)|uniprotkb:YIL124W(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11531209|imex:IM-24995-929	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157613(gene)|ensembl:ENST00000621158(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0070278"(extracellular matrix constituent secretion)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029805|mint:Q96BA8|reactome:R-HSA-8874211|refseq:NP_443086.1|entrezgene/locuslink:90993(identity)	sgd:S000001386|refseq:NP_012142.3|mint:P40471|dip:DIP-4614N|ensemblfungi:YIL124W(gene)|ensemblfungi:YIL124W_mRNA(transcript)|go:"GO:0000140"(acylglycerone-phosphate reductase activity)|go:"GO:0004806"(triglyceride lipase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0006654"(phosphatidic acid biosynthetic process)|go:"GO:0019433"(triglyceride catabolic process)|go:"GO:0102566"(1-acyl dihydroxyacetone phosphate reductase activity)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR020904|interpro:IPR036291|sgd:YIL124W(identity)	-	comment:mint|function:"Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE"	crc64:B614C0E0B1FB0CE0	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:sMWUFmBeBBCO+T0Y2CuB/un1lBg9606	rogid:WE4RmSXARj683MNUEsYGLis36Xo559292	intact-crc:AA4A27420F1D9D79|rigid:PIdRZmUwxOaR2abQ9jw56/9k5Oo	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O43186	uniprotkb:P40482	intact:EBI-748171|uniprotkb:Q0QD45|ensembl:ENSP00000221996|ensembl:ENSP00000445565	intact:EBI-16592|ensemblfungi:YIL109C|uniprotkb:D6VVH8	psi-mi:crx_human(display_long)|uniprotkb:CRX(gene name)|psi-mi:CRX(display_short)|uniprotkb:CORD2(gene name synonym)	psi-mi:sec24_yeast(display_long)|uniprotkb:SEC24(gene name)|psi-mi:SEC24(display_short)|uniprotkb:Abnormal nuclear morphology 1(gene name synonym)|uniprotkb:ANU1(gene name synonym)|uniprotkb:YIL109C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11531258|imex:IM-24995-934	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000545.1|ensembl:ENSG00000105392(gene)|ensembl:ENST00000221996(transcript)|ensembl:ENST00000539067(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007601"(visual perception)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050896"(response to stimulus)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013851(Transcription factor Otx, C-terminal)|interpro:IPR017970|entrezgene/locuslink:1406(identity)	refseq:NP_012157.3|ensemblfungi:YIL109C(gene)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016236"(macroautophagy)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0070971"(endoplasmic reticulum exit site)|ensemblfungi:YIL109C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0090110"(COPII-coated vesicle cargo loading)|interpro:IPR006895(Zinc finger, Sec23/Sec24-type)|interpro:IPR006896(Sec23/Sec24 trunk region)|interpro:IPR006900(Sec23/Sec24 helical region)|interpro:IPR007123(Gelsolin region)|interpro:IPR012990(Sec23/Sec24 beta-sandwich)|interpro:IPR029006|interpro:IPR036174|interpro:IPR036175|interpro:IPR036180|go:"GO:0000149"(SNARE binding)|go:"GO:0000329"(fungal-type vacuole membrane)|interpro:IPR036465|interpro:IPR041742|rcsb pdb:1M2V|rcsb pdb:1PCX|rcsb pdb:1PD0|rcsb pdb:1PD1|rcsb pdb:4BZI|rcsb pdb:6GNI|rcsb pdb:6ZGA|reactome:R-SCE-204005|reactome:R-SCE-5694530|reactome:R-SCE-983170|go:"GO:0005048"(signal sequence binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|sgd:S000001371|dip:DIP-2233N|mint:P40482|sgd:YIL109C(identity)	-	-	crc64:35E2BDD24CC75899	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:v/bkO/0iLzq1Q2HtieWQQ40RF9M9606	rogid:e7ekVFzZJMZvfRUZ9Q2jDQ/hvs0559292	intact-crc:3951459CAF4E9666|rigid:9K4xOQkvhSsK+w7VgSKN3FAe70Y	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:G5E962	uniprotkb:P40481	intact:EBI-11525615|ensembl:ENSP00000328177	intact:EBI-25180|uniprotkb:D6VVH7|ensemblfungi:YIL110W	psi-mi:g5e962_human(display_long)|uniprotkb:hCG_1644200(orf name)|uniprotkb:MAGEA11(gene name)|psi-mi:MAGEA11(display_short)	psi-mi:hpm1_yeast(display_long)|uniprotkb:MNI1(gene name synonym)|uniprotkb:YIL110W(locus name)|uniprotkb:HPM1(gene name)|psi-mi:HPM1(display_short)|uniprotkb:Mitotic exit network interactor 1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11531247|imex:IM-24995-933	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001011544.1|ensembl:ENSG00000185247(gene)|ensembl:ENST00000333104(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016604"(nuclear body)|interpro:IPR002190(MAGE protein)|interpro:IPR021072|interpro:IPR030099|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|entrezgene/locuslink:4110(identity)	refseq:NP_012156.1|sgd:S000001372|dip:DIP-4710N|ensemblfungi:YIL110W(gene)|ensemblfungi:YIL110W_mRNA(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0018064"(protein-L-histidine N-tele-methyltransferase activity)|go:"GO:0042038"(peptidyl-histidine methylation, to form tele-methylhistidine)|go:"GO:0045903"(positive regulation of translational fidelity)|interpro:IPR019410|sgd:YIL110W(identity)	-	-	crc64:C90C67433B5BCA7A	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:sVB0aA6yibWUx/d2SE+pwpKKgtI9606	rogid:hoAVij8oaANAGDSPMwh+IW39rn8559292	intact-crc:5C330D6ABA3B5C2B|rigid:mtUIaU+R0fXUT35sYcjU6W1thdo	false	sufficient binding region:82-400	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q5T124-6	uniprotkb:P40482	intact:EBI-11524408	intact:EBI-16592|ensemblfungi:YIL109C|uniprotkb:D6VVH8	psi-mi:q5t124-6(display_long)|uniprotkb:UBXN11(gene name)|psi-mi:UBXN11(display_short)|uniprotkb:Colorectal tumor-associated antigen COA-1(gene name synonym)|uniprotkb:SOC(gene name synonym)|uniprotkb:Socius(gene name synonym)|uniprotkb:UBX domain-containing protein 5(gene name synonym)|uniprotkb:UBXD5(gene name synonym)|uniprotkb:PP2243(orf name)	psi-mi:sec24_yeast(display_long)|uniprotkb:SEC24(gene name)|psi-mi:SEC24(display_short)|uniprotkb:Abnormal nuclear morphology 1(gene name synonym)|uniprotkb:ANU1(gene name synonym)|uniprotkb:YIL109C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11531296|imex:IM-24995-938	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-746004(isoform-parent)|uniprotkb:Q5T124-6(isoform-parent)|entrezgene/locuslink:91544(identity)	refseq:NP_012157.3|ensemblfungi:YIL109C(gene)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016236"(macroautophagy)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0070971"(endoplasmic reticulum exit site)|ensemblfungi:YIL109C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0090110"(COPII-coated vesicle cargo loading)|interpro:IPR006895(Zinc finger, Sec23/Sec24-type)|interpro:IPR006896(Sec23/Sec24 trunk region)|interpro:IPR006900(Sec23/Sec24 helical region)|interpro:IPR007123(Gelsolin region)|interpro:IPR012990(Sec23/Sec24 beta-sandwich)|interpro:IPR029006|interpro:IPR036174|interpro:IPR036175|interpro:IPR036180|go:"GO:0000149"(SNARE binding)|go:"GO:0000329"(fungal-type vacuole membrane)|interpro:IPR036465|interpro:IPR041742|rcsb pdb:1M2V|rcsb pdb:1PCX|rcsb pdb:1PD0|rcsb pdb:1PD1|rcsb pdb:4BZI|rcsb pdb:6GNI|rcsb pdb:6ZGA|reactome:R-SCE-204005|reactome:R-SCE-5694530|reactome:R-SCE-983170|go:"GO:0005048"(signal sequence binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|sgd:S000001371|dip:DIP-2233N|mint:P40482|sgd:YIL109C(identity)	-	-	crc64:35E2BDD24CC75899	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:1YSjG/p2ihcjl4P8KdPCaX2HxiY9606	rogid:e7ekVFzZJMZvfRUZ9Q2jDQ/hvs0559292	intact-crc:FD738A039CF211DF|rigid:9dTYfYSi8mp0xvSI86f7WG71xgw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q5JST6	uniprotkb:P40482	intact:EBI-2349927|uniprotkb:Q9H653|uniprotkb:Q5JST8|uniprotkb:Q68DK4|uniprotkb:Q8NEI0|intact:EBI-28971886|ensembl:ENSP00000404232	intact:EBI-16592|ensemblfungi:YIL109C|uniprotkb:D6VVH8	psi-mi:efhc2_human(display_long)|uniprotkb:EFHC2(gene name)|psi-mi:EFHC2(display_short)	psi-mi:sec24_yeast(display_long)|uniprotkb:SEC24(gene name)|psi-mi:SEC24(display_short)|uniprotkb:Abnormal nuclear morphology 1(gene name synonym)|uniprotkb:ANU1(gene name synonym)|uniprotkb:YIL109C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11531287|imex:IM-24995-937	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000404232|refseq:NP_079460.2|ensembl:ENSG00000183690(gene)|ensembl:ENST00000420999(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005930"(axoneme)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0060285"(cilium-dependent cell motility)|go:"GO:0072686"(mitotic spindle)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR006602(Region of unknown function DM10)|interpro:IPR011992(EF-Hand type)|interpro:IPR040193|rcsb pdb:2Z13|rcsb pdb:2Z14|entrezgene/locuslink:80258(identity)	refseq:NP_012157.3|ensemblfungi:YIL109C(gene)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016236"(macroautophagy)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0070971"(endoplasmic reticulum exit site)|ensemblfungi:YIL109C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0090110"(COPII-coated vesicle cargo loading)|interpro:IPR006895(Zinc finger, Sec23/Sec24-type)|interpro:IPR006896(Sec23/Sec24 trunk region)|interpro:IPR006900(Sec23/Sec24 helical region)|interpro:IPR007123(Gelsolin region)|interpro:IPR012990(Sec23/Sec24 beta-sandwich)|interpro:IPR029006|interpro:IPR036174|interpro:IPR036175|interpro:IPR036180|go:"GO:0000149"(SNARE binding)|go:"GO:0000329"(fungal-type vacuole membrane)|interpro:IPR036465|interpro:IPR041742|rcsb pdb:1M2V|rcsb pdb:1PCX|rcsb pdb:1PD0|rcsb pdb:1PD1|rcsb pdb:4BZI|rcsb pdb:6GNI|rcsb pdb:6ZGA|reactome:R-SCE-204005|reactome:R-SCE-5694530|reactome:R-SCE-983170|go:"GO:0005048"(signal sequence binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|sgd:S000001371|dip:DIP-2233N|mint:P40482|sgd:YIL109C(identity)	-	-	crc64:35E2BDD24CC75899	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:O1XriQSkLcYkk7H7AlanQ1FKIBY9606	rogid:e7ekVFzZJMZvfRUZ9Q2jDQ/hvs0559292	intact-crc:5DA65E526999FC1A|rigid:K+jf9WcEspZ15KZ93IpZr04HG7I	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40482	uniprotkb:P48775	intact:EBI-16592|ensemblfungi:YIL109C|uniprotkb:D6VVH8	intact:EBI-743494|ensembl:ENSP00000444788|ensembl:ENSP00000460086|uniprotkb:A8K053	psi-mi:sec24_yeast(display_long)|uniprotkb:SEC24(gene name)|psi-mi:SEC24(display_short)|uniprotkb:Abnormal nuclear morphology 1(gene name synonym)|uniprotkb:ANU1(gene name synonym)|uniprotkb:YIL109C(locus name)	psi-mi:t23o_human(display_long)|uniprotkb:Tryptophan pyrrolase(gene name synonym)|uniprotkb:Tryptophan oxygenase(gene name synonym)|uniprotkb:Tryptamin 2,3-dioxygenase(gene name synonym)|uniprotkb:TDO2(gene name)|psi-mi:TDO2(display_short)|uniprotkb:TDO(gene name synonym)|uniprotkb:Tryptophanase(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11531278|imex:IM-24995-936	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012157.3|ensemblfungi:YIL109C(gene)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016236"(macroautophagy)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0070971"(endoplasmic reticulum exit site)|ensemblfungi:YIL109C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0090110"(COPII-coated vesicle cargo loading)|interpro:IPR006895(Zinc finger, Sec23/Sec24-type)|interpro:IPR006896(Sec23/Sec24 trunk region)|interpro:IPR006900(Sec23/Sec24 helical region)|interpro:IPR007123(Gelsolin region)|interpro:IPR012990(Sec23/Sec24 beta-sandwich)|interpro:IPR029006|interpro:IPR036174|interpro:IPR036175|interpro:IPR036180|go:"GO:0000149"(SNARE binding)|go:"GO:0000329"(fungal-type vacuole membrane)|interpro:IPR036465|interpro:IPR041742|rcsb pdb:1M2V|rcsb pdb:1PCX|rcsb pdb:1PD0|rcsb pdb:1PD1|rcsb pdb:4BZI|rcsb pdb:6GNI|rcsb pdb:6ZGA|reactome:R-SCE-204005|reactome:R-SCE-5694530|reactome:R-SCE-983170|go:"GO:0005048"(signal sequence binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|sgd:S000001371|dip:DIP-2233N|mint:P40482|sgd:YIL109C(identity)	ensembl:ENSG00000151790(gene)|ensembl:ENSG00000262635(gene)|ensembl:ENST00000536354(transcript)|ensembl:ENST00000573403(transcript)|go:"GO:0004833"(tryptophan 2,3-dioxygenase activity)|go:"GO:0005829"(cytosol)|go:"GO:0016597"(amino acid binding)|go:"GO:0019441"(tryptophan catabolic process to kynurenine)|go:"GO:0019442"(tryptophan catabolic process to acetyl-CoA)|go:"GO:0019825"(oxygen binding)|go:"GO:0020037"(heme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051289"(protein homotetramerization)|go:"GO:1904842"(response to nitroglycerin)|interpro:IPR004981(Tryptophan 2,3-dioxygenase)|interpro:IPR037217|mint:P48775|rcsb pdb:4PW8|rcsb pdb:5TI9|rcsb pdb:5TIA|rcsb pdb:6A4I|rcsb pdb:6PYY|rcsb pdb:6PYZ|rcsb pdb:6UD5|rcsb pdb:6VBN|reactome:R-HSA-71240|refseq:NP_005642.1|entrezgene/locuslink:6999(identity)	-	crc64:35E2BDD24CC75899	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:e7ekVFzZJMZvfRUZ9Q2jDQ/hvs0559292	rogid:S+cyc710I52nIFQWgKhXFul9QZw9606	intact-crc:2D6F53B59BEFC440|rigid:e1ekJe+ubt+dKlyu1GO5jSgwoVw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O76081-6	uniprotkb:P40482	intact:EBI-10178530|ensembl:ENSP00000276500	intact:EBI-16592|ensemblfungi:YIL109C|uniprotkb:D6VVH8	psi-mi:o76081-6(display_long)|uniprotkb:RGS20(gene name)|psi-mi:RGS20(display_short)|uniprotkb:Gz-selective GTPase-activating protein(gene name synonym)|uniprotkb:RGSZ1(gene name synonym)|uniprotkb:Regulator of G-protein signaling Z1(gene name synonym)|uniprotkb:Regulator of Gz-selective protein signaling 1(gene name synonym)|uniprotkb:ZGAP1(gene name synonym)	psi-mi:sec24_yeast(display_long)|uniprotkb:SEC24(gene name)|psi-mi:SEC24(display_short)|uniprotkb:Abnormal nuclear morphology 1(gene name synonym)|uniprotkb:ANU1(gene name synonym)|uniprotkb:YIL109C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11531267|imex:IM-24995-935	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-1052678(isoform-parent)|uniprotkb:O76081-6(isoform-parent)|ensembl:ENSG00000147509(gene)|ensembl:ENST00000276500(transcript)|entrezgene/locuslink:8601(identity)	refseq:NP_012157.3|ensemblfungi:YIL109C(gene)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016236"(macroautophagy)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0070971"(endoplasmic reticulum exit site)|ensemblfungi:YIL109C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0090110"(COPII-coated vesicle cargo loading)|interpro:IPR006895(Zinc finger, Sec23/Sec24-type)|interpro:IPR006896(Sec23/Sec24 trunk region)|interpro:IPR006900(Sec23/Sec24 helical region)|interpro:IPR007123(Gelsolin region)|interpro:IPR012990(Sec23/Sec24 beta-sandwich)|interpro:IPR029006|interpro:IPR036174|interpro:IPR036175|interpro:IPR036180|go:"GO:0000149"(SNARE binding)|go:"GO:0000329"(fungal-type vacuole membrane)|interpro:IPR036465|interpro:IPR041742|rcsb pdb:1M2V|rcsb pdb:1PCX|rcsb pdb:1PD0|rcsb pdb:1PD1|rcsb pdb:4BZI|rcsb pdb:6GNI|rcsb pdb:6ZGA|reactome:R-SCE-204005|reactome:R-SCE-5694530|reactome:R-SCE-983170|go:"GO:0005048"(signal sequence binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|sgd:S000001371|dip:DIP-2233N|mint:P40482|sgd:YIL109C(identity)	-	-	crc64:35E2BDD24CC75899	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:5ddWx+4uSAxIhugOqlfdCIOD8sM9606	rogid:e7ekVFzZJMZvfRUZ9Q2jDQ/hvs0559292	intact-crc:B788224A861FD84F|rigid:YhPTliygjtLXzPH62nXn2agvctI	false	sufficient binding region:25-241	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40482	uniprotkb:Q9Y2W2	intact:EBI-16592|ensemblfungi:YIL109C|uniprotkb:D6VVH8	intact:EBI-714455|ensembl:ENSP00000261167|uniprotkb:Q96AY8	psi-mi:sec24_yeast(display_long)|uniprotkb:SEC24(gene name)|psi-mi:SEC24(display_short)|uniprotkb:Abnormal nuclear morphology 1(gene name synonym)|uniprotkb:ANU1(gene name synonym)|uniprotkb:YIL109C(locus name)	psi-mi:wbp11_human(display_long)|uniprotkb:SH3 domain-binding protein SNP70(gene name synonym)|uniprotkb:Npw38-binding protein(gene name synonym)|uniprotkb:WBP11(gene name)|psi-mi:WBP11(display_short)|uniprotkb:NPWBP(gene name synonym)|uniprotkb:SNP70(gene name synonym)|uniprotkb:SIPP1(gene name synonym)|uniprotkb:Splicing factor that interacts with PQBP-1 and PP1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11531332|imex:IM-24995-942	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012157.3|ensemblfungi:YIL109C(gene)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016236"(macroautophagy)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0070971"(endoplasmic reticulum exit site)|ensemblfungi:YIL109C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0090110"(COPII-coated vesicle cargo loading)|interpro:IPR006895(Zinc finger, Sec23/Sec24-type)|interpro:IPR006896(Sec23/Sec24 trunk region)|interpro:IPR006900(Sec23/Sec24 helical region)|interpro:IPR007123(Gelsolin region)|interpro:IPR012990(Sec23/Sec24 beta-sandwich)|interpro:IPR029006|interpro:IPR036174|interpro:IPR036175|interpro:IPR036180|go:"GO:0000149"(SNARE binding)|go:"GO:0000329"(fungal-type vacuole membrane)|interpro:IPR036465|interpro:IPR041742|rcsb pdb:1M2V|rcsb pdb:1PCX|rcsb pdb:1PD0|rcsb pdb:1PD1|rcsb pdb:4BZI|rcsb pdb:6GNI|rcsb pdb:6ZGA|reactome:R-SCE-204005|reactome:R-SCE-5694530|reactome:R-SCE-983170|go:"GO:0005048"(signal sequence binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|sgd:S000001371|dip:DIP-2233N|mint:P40482|sgd:YIL109C(identity)	rcsb pdb:7ABG|reactome:R-HSA-72163|ensembl:ENSG00000084463(gene)|ensembl:ENST00000261167(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045292"(mRNA cis splicing, via spliceosome)|go:"GO:0050699"(WW domain binding)|interpro:IPR019007|mint:Q9Y2W2|rcsb pdb:7ABF|refseq:NP_057396.1|entrezgene/locuslink:51729(identity)	-	crc64:35E2BDD24CC75899	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:e7ekVFzZJMZvfRUZ9Q2jDQ/hvs0559292	rogid:qE03bpSsQiJouJbn6ISt8DnD/pA9606	intact-crc:E3DE5882B0EB5C5C|rigid:dzrYIXOOYHA8fIJECJRnipXxixE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UPT5-1	uniprotkb:P40482	intact:EBI-6251402|ensembl:ENSP00000468404	intact:EBI-16592|ensemblfungi:YIL109C|uniprotkb:D6VVH8	psi-mi:q9upt5-1(display_long)|uniprotkb:EXOC7(gene name)|psi-mi:EXOC7(display_short)|uniprotkb:EXO70(gene name synonym)|uniprotkb:KIAA1067(gene name synonym)|uniprotkb:Exocyst complex component Exo70(gene name synonym)	psi-mi:sec24_yeast(display_long)|uniprotkb:SEC24(gene name)|psi-mi:SEC24(display_short)|uniprotkb:Abnormal nuclear morphology 1(gene name synonym)|uniprotkb:ANU1(gene name synonym)|uniprotkb:YIL109C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11531323|imex:IM-24995-941	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000182473(gene)|ensembl:ENST00000589210(transcript)|intact:EBI-720048(isoform-parent)|uniprotkb:Q9UPT5-1(isoform-parent)|entrezgene/locuslink:23265(identity)	refseq:NP_012157.3|ensemblfungi:YIL109C(gene)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016236"(macroautophagy)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0070971"(endoplasmic reticulum exit site)|ensemblfungi:YIL109C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0090110"(COPII-coated vesicle cargo loading)|interpro:IPR006895(Zinc finger, Sec23/Sec24-type)|interpro:IPR006896(Sec23/Sec24 trunk region)|interpro:IPR006900(Sec23/Sec24 helical region)|interpro:IPR007123(Gelsolin region)|interpro:IPR012990(Sec23/Sec24 beta-sandwich)|interpro:IPR029006|interpro:IPR036174|interpro:IPR036175|interpro:IPR036180|go:"GO:0000149"(SNARE binding)|go:"GO:0000329"(fungal-type vacuole membrane)|interpro:IPR036465|interpro:IPR041742|rcsb pdb:1M2V|rcsb pdb:1PCX|rcsb pdb:1PD0|rcsb pdb:1PD1|rcsb pdb:4BZI|rcsb pdb:6GNI|rcsb pdb:6ZGA|reactome:R-SCE-204005|reactome:R-SCE-5694530|reactome:R-SCE-983170|go:"GO:0005048"(signal sequence binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|sgd:S000001371|dip:DIP-2233N|mint:P40482|sgd:YIL109C(identity)	-	-	crc64:35E2BDD24CC75899	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:CKIeTOGXIWrHA1Duuw7x1ycRPoc9606	rogid:e7ekVFzZJMZvfRUZ9Q2jDQ/hvs0559292	intact-crc:221FE5CCE45EC703|rigid:2Mrw3Ks+1DL9VaeNNYSumHGSw9g	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40482	uniprotkb:Q9BYV6-2	intact:EBI-16592|ensemblfungi:YIL109C|uniprotkb:D6VVH8	intact:EBI-11522718|ensembl:ENSP00000297348	psi-mi:sec24_yeast(display_long)|uniprotkb:SEC24(gene name)|psi-mi:SEC24(display_short)|uniprotkb:Abnormal nuclear morphology 1(gene name synonym)|uniprotkb:ANU1(gene name synonym)|uniprotkb:YIL109C(locus name)	psi-mi:q9byv6-2(display_long)|uniprotkb:TRIM55(gene name)|psi-mi:TRIM55(display_short)|uniprotkb:MURF2(gene name synonym)|uniprotkb:Muscle-specific RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 29(gene name synonym)|uniprotkb:RNF29(gene name synonym)|uniprotkb:p50(isoform synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11531314|imex:IM-24995-940	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012157.3|ensemblfungi:YIL109C(gene)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016236"(macroautophagy)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0070971"(endoplasmic reticulum exit site)|ensemblfungi:YIL109C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0090110"(COPII-coated vesicle cargo loading)|interpro:IPR006895(Zinc finger, Sec23/Sec24-type)|interpro:IPR006896(Sec23/Sec24 trunk region)|interpro:IPR006900(Sec23/Sec24 helical region)|interpro:IPR007123(Gelsolin region)|interpro:IPR012990(Sec23/Sec24 beta-sandwich)|interpro:IPR029006|interpro:IPR036174|interpro:IPR036175|interpro:IPR036180|go:"GO:0000149"(SNARE binding)|go:"GO:0000329"(fungal-type vacuole membrane)|interpro:IPR036465|interpro:IPR041742|rcsb pdb:1M2V|rcsb pdb:1PCX|rcsb pdb:1PD0|rcsb pdb:1PD1|rcsb pdb:4BZI|rcsb pdb:6GNI|rcsb pdb:6ZGA|reactome:R-SCE-204005|reactome:R-SCE-5694530|reactome:R-SCE-983170|go:"GO:0005048"(signal sequence binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|sgd:S000001371|dip:DIP-2233N|mint:P40482|sgd:YIL109C(identity)	intact:EBI-2341179(isoform-parent)|uniprotkb:Q9BYV6-2(isoform-parent)|ensembl:ENSG00000147573(gene)|ensembl:ENST00000353317(transcript)|entrezgene/locuslink:84675(identity)	-	crc64:35E2BDD24CC75899	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:e7ekVFzZJMZvfRUZ9Q2jDQ/hvs0559292	rogid:9t8UhK+Z1yBqjnQrOqPD76NuXGg9606	intact-crc:09420AFF3D35A62A|rigid:KagW2q0P9FpPsKOn82dMJCHzfjw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96BR9	uniprotkb:P40482	intact:EBI-742740|uniprotkb:Q8IUL5|uniprotkb:Q8IWR9|uniprotkb:Q8N2Y5|uniprotkb:Q96BX0|ensembl:ENSP00000362609	intact:EBI-16592|ensemblfungi:YIL109C|uniprotkb:D6VVH8	psi-mi:zbt8a_human(display_long)|uniprotkb:ZBTB8A(gene name)|psi-mi:ZBTB8A(display_short)|uniprotkb:BOZF1(gene name synonym)|uniprotkb:BTB/POZ and zinc-finger domain-containing factor(gene name synonym)|uniprotkb:BTB/POZ and zinc-finger domains factor on chromosome 1(gene name synonym)	psi-mi:sec24_yeast(display_long)|uniprotkb:SEC24(gene name)|psi-mi:SEC24(display_short)|uniprotkb:Abnormal nuclear morphology 1(gene name synonym)|uniprotkb:ANU1(gene name synonym)|uniprotkb:YIL109C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11531305|imex:IM-24995-939	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000160062(gene)|ensembl:ENST00000373510(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|refseq:NP_001035531.2|refseq:NP_001278425.1|entrezgene/locuslink:653121(identity)	refseq:NP_012157.3|ensemblfungi:YIL109C(gene)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016236"(macroautophagy)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0070971"(endoplasmic reticulum exit site)|ensemblfungi:YIL109C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0090110"(COPII-coated vesicle cargo loading)|interpro:IPR006895(Zinc finger, Sec23/Sec24-type)|interpro:IPR006896(Sec23/Sec24 trunk region)|interpro:IPR006900(Sec23/Sec24 helical region)|interpro:IPR007123(Gelsolin region)|interpro:IPR012990(Sec23/Sec24 beta-sandwich)|interpro:IPR029006|interpro:IPR036174|interpro:IPR036175|interpro:IPR036180|go:"GO:0000149"(SNARE binding)|go:"GO:0000329"(fungal-type vacuole membrane)|interpro:IPR036465|interpro:IPR041742|rcsb pdb:1M2V|rcsb pdb:1PCX|rcsb pdb:1PD0|rcsb pdb:1PD1|rcsb pdb:4BZI|rcsb pdb:6GNI|rcsb pdb:6ZGA|reactome:R-SCE-204005|reactome:R-SCE-5694530|reactome:R-SCE-983170|go:"GO:0005048"(signal sequence binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|sgd:S000001371|dip:DIP-2233N|mint:P40482|sgd:YIL109C(identity)	-	-	crc64:35E2BDD24CC75899	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:tsrPT2tHvuBryODKgRXnceXz9s09606	rogid:e7ekVFzZJMZvfRUZ9Q2jDQ/hvs0559292	intact-crc:757CC9CED1D1FEEE|rigid:TGMPKDd80thAEsAmUjkZybJMmFc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40498	uniprotkb:Q9Y2D8	intact:EBI-25113|uniprotkb:D6VVJ6|ensemblfungi:YIL091C	intact:EBI-2212028|uniprotkb:B4DFE3|uniprotkb:J3KR02|uniprotkb:A8K8W0|uniprotkb:D3DT13|uniprotkb:Q6P2P8|uniprotkb:Q6ULS1|uniprotkb:Q7L168|uniprotkb:Q9UIX0|intact:EBI-10964529|ensembl:ENSP00000340279	psi-mi:utp25_yeast(display_long)|uniprotkb:YIL091C(locus name)|uniprotkb:UTP25(gene name)|psi-mi:UTP25(display_short)|uniprotkb:U three protein 25(gene name synonym)	psi-mi:adip_human(display_long)|uniprotkb:SSX2IP(gene name)|psi-mi:SSX2IP(display_short)|uniprotkb:KIAA0923(gene name synonym)|uniprotkb:Afadin DIL domain-interacting protein(gene name synonym)|uniprotkb:SSX2-interacting protein(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11531359|imex:IM-24995-945	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012175.1|sgd:S000001353|mint:P40498|dip:DIP-5629N|ensemblfungi:YIL091C(gene)|ensemblfungi:YIL091C_mRNA(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0019843"(rRNA binding)|go:"GO:0032040"(small-subunit processome)|go:"GO:0034511"(U3 snoRNA binding)|go:"GO:0042274"(ribosomal small subunit biogenesis)|interpro:IPR010678(Protein of unknown function DUF1253)|interpro:IPR027417|reactome:R-SCE-6791226|sgd:YIL091C(identity)	refseq:XP_011538912.1|refseq:NP_001159765.1|refseq:NP_001159766.1|refseq:NP_001159767.1|refseq:NP_001159889.1|refseq:NP_054740.3|refseq:XP_005270484.1|refseq:XP_005270485.1|refseq:XP_006710394.1|refseq:XP_016855723.1|ensembl:ENSG00000117155(gene)|ensembl:ENST00000342203(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005912"(adherens junction)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031252"(cell leading edge)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0035735"(intraciliary transport involved in cilium assembly)|go:"GO:0036064"(ciliary basal body)|go:"GO:0060271"(cilium assembly)|go:"GO:2000145"(regulation of cell motility)|interpro:IPR021622|mint:Q9Y2D8|entrezgene/locuslink:117178(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:9OTjSNDfUXoxYLjdDlhobs3AKa8559292	rogid:E0VeMRF9SrpQKSJFP01XEbMjeF89606	intact-crc:6AB7A81BFDCBC03F|rigid:0S6RBVnmIXiApeCgZprKXozyULk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40491	uniprotkb:O95273	intact:EBI-25141|uniprotkb:D6VVI9|ensemblfungi:YIL098C	intact:EBI-748961|uniprotkb:A8K3Q0|uniprotkb:A8K3U2|uniprotkb:Q6ZQN9|uniprotkb:Q7Z519|uniprotkb:Q8NBS7|uniprotkb:Q8NBY2|uniprotkb:Q9NS19|uniprotkb:Q9NYH3|uniprotkb:Q9UHX9|ensembl:ENSP00000300213	psi-mi:fmc1_yeast(display_long)|uniprotkb:Formation of mitochondrial complexes protein 1(gene name synonym)|uniprotkb:YIL098C(locus name)|uniprotkb:FMC1(gene name)|psi-mi:FMC1(display_short)	psi-mi:ccdb1_human(display_long)|uniprotkb:Grap2 and cyclin-D-interacting protein(gene name synonym)|uniprotkb:Human homolog of Maid(gene name synonym)|uniprotkb:CCNDBP1(gene name)|psi-mi:CCNDBP1(display_short)|uniprotkb:DIP1(gene name synonym)|uniprotkb:GCIP(gene name synonym)|uniprotkb:HHM(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11531350|imex:IM-24995-944	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000001360|refseq:NP_012168.3|mint:P40491|dip:DIP-5652N|ensemblfungi:YIL098C(gene)|ensemblfungi:YIL098C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0016236"(macroautophagy)|go:"GO:0033615"(mitochondrial proton-transporting ATP synthase complex assembly)|interpro:IPR039196|sgd:YIL098C(identity)	refseq:NP_036274.3|ensembl:ENSG00000166946(gene)|ensembl:ENST00000300213(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0016604"(nuclear body)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR026907|mint:O95273|rcsb pdb:3AY5|entrezgene/locuslink:23582(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:lGt1inZN/0++e/TWYR1mZnMBG2o559292	rogid:Vi9aoFc+Mov6P3X6KGmsTxXqxvM9606	intact-crc:8E4F507745F7DDD8|rigid:xf9fPRteokFBvM531dSYRH/F6jU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40487	uniprotkb:Q9BQC3	intact:EBI-25162|uniprotkb:D6VVI4|ensemblfungi:YIL103W	intact:EBI-10237931|uniprotkb:O60623|uniprotkb:B4DNI8|uniprotkb:B2RDE3|uniprotkb:A8MVC9|ensembl:ENSP00000255108	psi-mi:dph1_yeast(display_long)|uniprotkb:DPH1(gene name)|psi-mi:DPH1(display_short)|uniprotkb:Diphthamide biosynthesis protein 1(gene name synonym)|uniprotkb:Diphtheria toxin resistance protein 1(gene name synonym)|uniprotkb:"S-adenosyl-L-methionine:L-histidine 3-amino-3-carboxypropyltransferase 1"(gene name synonym)|uniprotkb:YIL103W(locus name)	psi-mi:dph2_human(display_long)|uniprotkb:Diphthamide biosynthesis protein 2(gene name synonym)|uniprotkb:Diphtheria toxin resistance protein 2(gene name synonym)|uniprotkb:DPH2(gene name)|psi-mi:DPH2(display_short)|uniprotkb:DPH2L2(gene name synonym)|uniprotkb:"S-adenosyl-L-methionine:L-histidine 3-amino-3-carboxypropyltransferase 2"(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11531341|imex:IM-24995-943	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012163.1|sgd:S000001365|mint:P40487|dip:DIP-5653N|ensemblfungi:YIL103W(gene)|ensemblfungi:YIL103W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0017183"(peptidyl-diphthamide biosynthetic process from peptidyl-histidine)|go:"GO:0090560"("2-(3-amino-3-carboxypropyl)histidine synthase activity")|interpro:IPR016435(Diphthamide synthesis, DHP1)|interpro:IPR035435|interpro:IPR042263|interpro:IPR042264|interpro:IPR042265|reactome:R-SCE-5358493|sgd:YIL103W(identity)	refseq:NP_001306095.1|refseq:NP_001306098.1|refseq:NP_001034678.1|refseq:NP_001375.2|ensembl:ENSG00000132768(gene)|ensembl:ENST00000255108(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0017183"(peptidyl-diphthamide biosynthetic process from peptidyl-histidine)|go:"GO:0090560"("2-(3-amino-3-carboxypropyl)histidine synthase activity")|interpro:IPR010014(Diphthamide synthesis, DHP2)|interpro:IPR016435(Diphthamide synthesis, DHP1)|interpro:IPR042263|interpro:IPR042265|reactome:R-HSA-5358493|entrezgene/locuslink:1802(identity)	-	crc64:22E93852E03C6722	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:zk1Esuvz7u5GtymKbFzfv+PFAPQ559292	rogid:/Z9UhAa8qkHe3rPFS3OPfiJ4RFM9606	intact-crc:21B427EED19C4E80|rigid:2KWZtj6bcqiQy22WKS9+Eu5pQSw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40507	uniprotkb:O14641	intact:EBI-25083|uniprotkb:D6VVK5|ensemblfungi:YIL079C	intact:EBI-740850|ensembl:ENSP00000005340|uniprotkb:Q53XM0|uniprotkb:D3DTN3	psi-mi:air1_yeast(display_long)|uniprotkb:Arginine methyltransferase-interacting RING finger protein 1(gene name synonym)|uniprotkb:AIR1(gene name)|psi-mi:AIR1(display_short)|uniprotkb:YIL079C(locus name)	psi-mi:dvl2_human(display_long)|uniprotkb:DSH homolog 2(gene name synonym)|uniprotkb:DVL2(gene name)|psi-mi:DVL2(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11531388|imex:IM-24995-948	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012186.1|sgd:S000001341|mint:P40507|dip:DIP-2700N|ensemblfungi:YIL079C(gene)|ensemblfungi:YIL079C_mRNA(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031499"(TRAMP complex)|go:"GO:0043629"(ncRNA polyadenylation)|go:"GO:0071031"(nuclear mRNA surveillance of mRNA 3'-end processing)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071036"(nuclear polyadenylation-dependent snoRNA catabolic process)|go:"GO:0071037"(nuclear polyadenylation-dependent snRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071039"(nuclear polyadenylation-dependent CUT catabolic process)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR016713("Poly(A) polymerase complex, Air1/2")|interpro:IPR036875|sgd:YIL079C(identity)	refseq:NP_004413.1|ensembl:ENSG00000004975(gene)|ensembl:ENST00000005340(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005109"(frizzled binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0007507"(heart development)|go:"GO:0016235"(aggresome)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044340"(canonical Wnt signaling pathway involved in regulation of cell proliferation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0150012"(positive regulation of neuron projection arborization)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008341(Dishevelled-2 region)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:O14641|rcsb pdb:2REY|rcsb pdb:3CBX|rcsb pdb:3CBY|rcsb pdb:3CBZ|rcsb pdb:3CC0|rcsb pdb:4WIP|rcsb pdb:5LNP|rcsb pdb:5SUY|rcsb pdb:5SUZ|rcsb pdb:6IW3|rcsb pdb:6JCK|reactome:R-HSA-201681|reactome:R-HSA-201688|reactome:R-HSA-2028269|reactome:R-HSA-4086400|reactome:R-HSA-4608870|reactome:R-HSA-4641258|reactome:R-HSA-4641262|reactome:R-HSA-5099900|reactome:R-HSA-5368598|reactome:R-HSA-5663220|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9673324|ensembl:ENSP00000005340|dip:DIP-34433N|entrezgene/locuslink:1856(identity)	-	crc64:3CA920FA1204EC9C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:myPxXwP+mJgvoh50PLYk2Q3GMh4559292	rogid:2Vdc8oRnT4Mz/j+EXQXrL3AszOc9606	intact-crc:1F56DEF8162B737B|rigid:57oxXwgEOJrXbemx21HDveUyELo	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8N5R6	uniprotkb:P40507	intact:EBI-740841|intact:EBI-953781|uniprotkb:B3KQ49|uniprotkb:A8K3U4|uniprotkb:A8MPQ6|uniprotkb:A8MV61|uniprotkb:A8MVU9|uniprotkb:Q9H5Q6|uniprotkb:Q8TAX6|intact:EBI-2320546|intact:EBI-11522976	intact:EBI-25083|uniprotkb:D6VVK5|ensemblfungi:YIL079C	psi-mi:ccd33_human(display_long)|uniprotkb:CCDC33(gene name)|psi-mi:CCDC33(display_short)|uniprotkb:Cancer/testis antigen 61(gene name synonym)	psi-mi:air1_yeast(display_long)|uniprotkb:Arginine methyltransferase-interacting RING finger protein 1(gene name synonym)|uniprotkb:AIR1(gene name)|psi-mi:AIR1(display_short)|uniprotkb:YIL079C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11531379|imex:IM-24995-947	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_079331.3|interpro:IPR000008(C2 calcium-dependent membrane targeting)|go:"GO:0005777"(peroxisome)|refseq:NP_001274110.1|refseq:NP_877592.2|mint:Q8N5R6|interpro:IPR035892|interpro:IPR039889|entrezgene/locuslink:80125(identity)	refseq:NP_012186.1|sgd:S000001341|mint:P40507|dip:DIP-2700N|ensemblfungi:YIL079C(gene)|ensemblfungi:YIL079C_mRNA(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031499"(TRAMP complex)|go:"GO:0043629"(ncRNA polyadenylation)|go:"GO:0071031"(nuclear mRNA surveillance of mRNA 3'-end processing)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071036"(nuclear polyadenylation-dependent snoRNA catabolic process)|go:"GO:0071037"(nuclear polyadenylation-dependent snRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071039"(nuclear polyadenylation-dependent CUT catabolic process)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR016713("Poly(A) polymerase complex, Air1/2")|interpro:IPR036875|sgd:YIL079C(identity)	-	-	crc64:3CA920FA1204EC9C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2021/11/30	rogid:eEIn7pQyfdHWx8TeLJpYy0i/gww9606	rogid:myPxXwP+mJgvoh50PLYk2Q3GMh4559292	intact-crc:136D985BF9FED987|rigid:cim1x7HrbAQekz/HjixosQzWvzM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96BA8	uniprotkb:P40501	intact:EBI-6942903|ensembl:ENSP00000481956|intact:MINT-268046|intact:MINT-8162577|uniprotkb:Q8N2D5|uniprotkb:Q96CP0	intact:EBI-11531370|uniprotkb:D6VVJ9|ensemblfungi:YIL088C	psi-mi:cr3l1_human(display_long)|uniprotkb:CREB3L1(gene name)|psi-mi:CREB3L1(display_short)|uniprotkb:OASIS(gene name synonym)|uniprotkb:PSEC0238(orf name)|uniprotkb:Old astrocyte specifically-induced substance(gene name synonym)	psi-mi:avt7_yeast(display_long)|uniprotkb:AVT7(gene name)|psi-mi:AVT7(display_short)|uniprotkb:YIL088C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11531368|imex:IM-24995-946	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157613(gene)|ensembl:ENST00000621158(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0070278"(extracellular matrix constituent secretion)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029805|mint:Q96BA8|reactome:R-HSA-8874211|refseq:NP_443086.1|entrezgene/locuslink:90993(identity)	refseq:NP_012178.1|sgd:S000001350|ensemblfungi:YIL088C(gene)|ensemblfungi:YIL088C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0003333"(amino acid transmembrane transport)|go:"GO:0005290"(L-histidine transmembrane transporter activity)|go:"GO:0005302"(L-tyrosine transmembrane transporter activity)|go:"GO:0005313"(L-glutamate transmembrane transporter activity)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006865"(amino acid transport)|go:"GO:0015171"(amino acid transmembrane transporter activity)|go:"GO:0015189"(L-lysine transmembrane transporter activity)|go:"GO:0015194"(L-serine transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0043937"(regulation of sporulation)|go:"GO:0061459"(L-arginine transmembrane transporter activity)|interpro:IPR013057(Amino acid transporter, transmembrane)|dip:DIP-7299N|sgd:YIL088C(identity)	-	comment:mint|function:"Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE"	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/03/16	rogid:sMWUFmBeBBCO+T0Y2CuB/un1lBg9606	rogid:h/wTkn7UHQvjASI16kH6WV6wtC8559292	intact-crc:39E1D2FEAC998E21|rigid:w+mz918KyG6WmrOmroEz0EEF4YQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P07910-2	uniprotkb:P40507	intact:EBI-5280084|ensembl:ENSP00000442816|ensembl:ENSP00000450544|ensembl:ENSP00000450725|ensembl:ENSP00000451176	intact:EBI-25083|uniprotkb:D6VVK5|ensemblfungi:YIL079C	psi-mi:p07910-2(display_long)|uniprotkb:HNRNPC(gene name)|psi-mi:HNRNPC(display_short)|uniprotkb:HNRPC(gene name synonym)	psi-mi:air1_yeast(display_long)|uniprotkb:Arginine methyltransferase-interacting RING finger protein 1(gene name synonym)|uniprotkb:AIR1(gene name)|psi-mi:AIR1(display_short)|uniprotkb:YIL079C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11531397|imex:IM-24995-949	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:P07910-2(isoform-parent)|intact:EBI-357966(isoform-parent)|ensembl:ENSG00000092199(gene)|ensembl:ENST00000430246(transcript)|ensembl:ENST00000553300(transcript)|ensembl:ENST00000554969(transcript)|ensembl:ENST00000556897(transcript)|entrezgene/locuslink:3183(identity)	refseq:NP_012186.1|sgd:S000001341|mint:P40507|dip:DIP-2700N|ensemblfungi:YIL079C(gene)|ensemblfungi:YIL079C_mRNA(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031499"(TRAMP complex)|go:"GO:0043629"(ncRNA polyadenylation)|go:"GO:0071031"(nuclear mRNA surveillance of mRNA 3'-end processing)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071036"(nuclear polyadenylation-dependent snoRNA catabolic process)|go:"GO:0071037"(nuclear polyadenylation-dependent snRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071039"(nuclear polyadenylation-dependent CUT catabolic process)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR016713("Poly(A) polymerase complex, Air1/2")|interpro:IPR036875|sgd:YIL079C(identity)	-	isoform-comment:Contains a phosphoserine at position 107. Contains a phosphoserine at position 108.	crc64:3CA920FA1204EC9C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:r7AhGozE3aHdynLr8DrXPRtOuyI9606	rogid:myPxXwP+mJgvoh50PLYk2Q3GMh4559292	intact-crc:3F033CBCDE67360C|rigid:Sc9prlxF38fvgxdgRooc5Z7hWGM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38159	uniprotkb:P40507	intact:EBI-743526|ensembl:ENSP00000359645|uniprotkb:Q5JQ67|uniprotkb:Q969R3|uniprotkb:D3DWH0|uniprotkb:E9PG86|uniprotkb:Q8N8Y7|uniprotkb:B4E3U4	intact:EBI-25083|uniprotkb:D6VVK5|ensemblfungi:YIL079C	psi-mi:rbmx_human(display_long)|uniprotkb:Glycoprotein p43(gene name synonym)|uniprotkb:RBMX(gene name)|psi-mi:RBMX(display_short)|uniprotkb:HNRPG(gene name synonym)|uniprotkb:RBMXP1(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein G(gene name synonym)	psi-mi:air1_yeast(display_long)|uniprotkb:Arginine methyltransferase-interacting RING finger protein 1(gene name synonym)|uniprotkb:AIR1(gene name)|psi-mi:AIR1(display_short)|uniprotkb:YIL079C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11531418|imex:IM-24995-951	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000147274(gene)|ensembl:ENST00000320676(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000791"(euchromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0044530"(supraspliceosomal complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0006509"(membrane protein ectodomain proteolysis)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012604(RBM1CTR)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|mint:P38159|rcsb pdb:2MB0|rcsb pdb:2MKS|reactome:R-HSA-72163|reactome:R-HSA-72203|reactome:R-HSA-9013418|reactome:R-HSA-9013422|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273|refseq:NP_002130.2|refseq:NP_001158275.1|dip:DIP-34447N|entrezgene/locuslink:27316(identity)	refseq:NP_012186.1|sgd:S000001341|mint:P40507|dip:DIP-2700N|ensemblfungi:YIL079C(gene)|ensemblfungi:YIL079C_mRNA(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031499"(TRAMP complex)|go:"GO:0043629"(ncRNA polyadenylation)|go:"GO:0071031"(nuclear mRNA surveillance of mRNA 3'-end processing)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071036"(nuclear polyadenylation-dependent snoRNA catabolic process)|go:"GO:0071037"(nuclear polyadenylation-dependent snRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071039"(nuclear polyadenylation-dependent CUT catabolic process)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR016713("Poly(A) polymerase complex, Air1/2")|interpro:IPR036875|sgd:YIL079C(identity)	-	-	crc64:3CA920FA1204EC9C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:ocCkdy9PxjeVLUQf0tMVCEhFfO89606	rogid:myPxXwP+mJgvoh50PLYk2Q3GMh4559292	intact-crc:146ACDC0310D0445|rigid:/BQgaVjBAPbAXp3cUMSPBC9hM5w	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P15622-3	uniprotkb:P40507	intact:EBI-10177272|ensembl:ENSP00000393442	intact:EBI-25083|uniprotkb:D6VVK5|ensemblfungi:YIL079C	psi-mi:p15622-3(display_long)|uniprotkb:ZNF647(gene name synonym)|uniprotkb:Zinc finger protein 647(gene name synonym)|uniprotkb:ZNF250(gene name)|psi-mi:ZNF250(display_short)	psi-mi:air1_yeast(display_long)|uniprotkb:Arginine methyltransferase-interacting RING finger protein 1(gene name synonym)|uniprotkb:AIR1(gene name)|psi-mi:AIR1(display_short)|uniprotkb:YIL079C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11531407|imex:IM-24995-950	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000196150(gene)|ensembl:ENST00000417550(transcript)|intact:EBI-739678(isoform-parent)|uniprotkb:P15622-3(isoform-parent)|entrezgene/locuslink:58500(identity)	refseq:NP_012186.1|sgd:S000001341|mint:P40507|dip:DIP-2700N|ensemblfungi:YIL079C(gene)|ensemblfungi:YIL079C_mRNA(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031499"(TRAMP complex)|go:"GO:0043629"(ncRNA polyadenylation)|go:"GO:0071031"(nuclear mRNA surveillance of mRNA 3'-end processing)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071036"(nuclear polyadenylation-dependent snoRNA catabolic process)|go:"GO:0071037"(nuclear polyadenylation-dependent snRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071039"(nuclear polyadenylation-dependent CUT catabolic process)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR016713("Poly(A) polymerase complex, Air1/2")|interpro:IPR036875|sgd:YIL079C(identity)	-	isoform-comment:No experimental confirmation available.	crc64:3CA920FA1204EC9C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:4AVjeOREEATULMJWtdeZt7rhi889606	rogid:myPxXwP+mJgvoh50PLYk2Q3GMh4559292	intact-crc:F90F42EE268D210B|rigid:Dk5IFw8zoK+HyqUvFGaAk0kqfz4	false	sufficient binding region:46-555	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40507	uniprotkb:Q8WTR7	intact:EBI-25083|uniprotkb:D6VVK5|ensemblfungi:YIL079C	intact:EBI-751409|uniprotkb:Q9ULS9|uniprotkb:Q9Y4Q7|uniprotkb:A8K8T7|intact:EBI-28978826|ensembl:ENSP00000270617|ensembl:ENSP00000375697|ensembl:ENSP00000472808	psi-mi:air1_yeast(display_long)|uniprotkb:Arginine methyltransferase-interacting RING finger protein 1(gene name synonym)|uniprotkb:AIR1(gene name)|psi-mi:AIR1(display_short)|uniprotkb:YIL079C(locus name)	psi-mi:zn473_human(display_long)|uniprotkb:Zinc finger protein 100 homolog(gene name synonym)|uniprotkb:ZNF473(gene name)|psi-mi:ZNF473(display_short)|uniprotkb:KIAA1141(gene name synonym)|uniprotkb:ZFP100(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11531445|imex:IM-24995-954	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012186.1|sgd:S000001341|mint:P40507|dip:DIP-2700N|ensemblfungi:YIL079C(gene)|ensemblfungi:YIL079C_mRNA(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031499"(TRAMP complex)|go:"GO:0043629"(ncRNA polyadenylation)|go:"GO:0071031"(nuclear mRNA surveillance of mRNA 3'-end processing)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071036"(nuclear polyadenylation-dependent snoRNA catabolic process)|go:"GO:0071037"(nuclear polyadenylation-dependent snRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071039"(nuclear polyadenylation-dependent CUT catabolic process)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR016713("Poly(A) polymerase complex, Air1/2")|interpro:IPR036875|sgd:YIL079C(identity)	refseq:NP_001006657.1|refseq:NP_056243.1|ensembl:ENSP00000270617|ensembl:ENSP00000375697|ensembl:ENSP00000472808|refseq:NP_001295353.1|ensembl:ENSG00000142528(gene)|ensembl:ENST00000270617(transcript)|ensembl:ENST00000391821(transcript)|ensembl:ENST00000595661(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006398"(mRNA 3'-end processing by stem-loop binding and cleavage)|go:"GO:0015030"(Cajal body)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|rcsb pdb:2EMB|rcsb pdb:2EMC|rcsb pdb:2EME|rcsb pdb:2EOU|rcsb pdb:2EOX|rcsb pdb:2EOY|rcsb pdb:2EOZ|rcsb pdb:2YRH|rcsb pdb:2YRJ|rcsb pdb:2YSV|rcsb pdb:2YTD|rcsb pdb:2YTE|rcsb pdb:2YTT|rcsb pdb:2YU5|reactome:R-HSA-111367|reactome:R-HSA-212436|reactome:R-HSA-73856|reactome:R-HSA-77588|entrezgene/locuslink:25888(identity)	-	crc64:3CA920FA1204EC9C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:myPxXwP+mJgvoh50PLYk2Q3GMh4559292	rogid:Tm+mqhJ8JVqLYFprsek+VYhcnOI9606	intact-crc:E9C3330E24E89A81|rigid:mIzg72Yp2WZuS2yd/ygpPJ4s6Xg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40507	uniprotkb:Q8NHQ1	intact:EBI-25083|uniprotkb:D6VVK5|ensemblfungi:YIL079C	intact:EBI-739624|ensembl:ENSP00000264982|ensembl:ENSP00000419231|uniprotkb:Q96B31|uniprotkb:Q9H2C3|uniprotkb:Q9H2Z1|uniprotkb:Q9H940|uniprotkb:D3DNE9|uniprotkb:B7Z5I8|uniprotkb:B7Z7E8|uniprotkb:F5GZX8	psi-mi:air1_yeast(display_long)|uniprotkb:Arginine methyltransferase-interacting RING finger protein 1(gene name synonym)|uniprotkb:AIR1(gene name)|psi-mi:AIR1(display_short)|uniprotkb:YIL079C(locus name)	psi-mi:cep70_human(display_long)|uniprotkb:CEP70(gene name)|psi-mi:CEP70(display_short)|uniprotkb:BITE(gene name synonym)|uniprotkb:p10-binding protein(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11531436|imex:IM-24995-953	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012186.1|sgd:S000001341|mint:P40507|dip:DIP-2700N|ensemblfungi:YIL079C(gene)|ensemblfungi:YIL079C_mRNA(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031499"(TRAMP complex)|go:"GO:0043629"(ncRNA polyadenylation)|go:"GO:0071031"(nuclear mRNA surveillance of mRNA 3'-end processing)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071036"(nuclear polyadenylation-dependent snoRNA catabolic process)|go:"GO:0071037"(nuclear polyadenylation-dependent snRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071039"(nuclear polyadenylation-dependent CUT catabolic process)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR016713("Poly(A) polymerase complex, Air1/2")|interpro:IPR036875|sgd:YIL079C(identity)	ensembl:ENSG00000114107(gene)|ensembl:ENST00000264982(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|interpro:IPR019734|interpro:IPR037692|mint:Q8NHQ1|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|ensembl:ENST00000484888(transcript)|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_077817.2|refseq:XP_016862764.1|refseq:NP_001275893.1|refseq:NP_001275894.1|refseq:NP_001275895.1|refseq:NP_001275896.1|refseq:NP_001307527.1|refseq:NP_001307529.1|entrezgene/locuslink:80321(identity)	-	crc64:3CA920FA1204EC9C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:myPxXwP+mJgvoh50PLYk2Q3GMh4559292	rogid:S4yveQWcvdVtAUX65gqrJ5Dv0Mc9606	intact-crc:7DC96319391580C7|rigid:Hfww7CA+cje4UceaTeAirQcFeIg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40507	uniprotkb:Q5VWX1	intact:EBI-25083|uniprotkb:D6VVK5|ensemblfungi:YIL079C	intact:EBI-742808|uniprotkb:Q8TCZ4|uniprotkb:Q8N4I4|uniprotkb:A8K7M8|ensembl:ENSP00000281156	psi-mi:air1_yeast(display_long)|uniprotkb:Arginine methyltransferase-interacting RING finger protein 1(gene name synonym)|uniprotkb:AIR1(gene name)|psi-mi:AIR1(display_short)|uniprotkb:YIL079C(locus name)	psi-mi:khdr2_human(display_long)|uniprotkb:SLM1(gene name synonym)|uniprotkb:Sam68-like mammalian protein 1(gene name synonym)|uniprotkb:KHDRBS2(gene name)|psi-mi:KHDRBS2(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11531427|imex:IM-24995-952	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012186.1|sgd:S000001341|mint:P40507|dip:DIP-2700N|ensemblfungi:YIL079C(gene)|ensemblfungi:YIL079C_mRNA(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031499"(TRAMP complex)|go:"GO:0043629"(ncRNA polyadenylation)|go:"GO:0071031"(nuclear mRNA surveillance of mRNA 3'-end processing)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071036"(nuclear polyadenylation-dependent snoRNA catabolic process)|go:"GO:0071037"(nuclear polyadenylation-dependent snRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071039"(nuclear polyadenylation-dependent CUT catabolic process)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR016713("Poly(A) polymerase complex, Air1/2")|interpro:IPR036875|sgd:YIL079C(identity)	refseq:NP_689901.2|ensembl:ENSG00000112232(gene)|ensembl:ENST00000281156(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008143"("poly(A) binding")|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0017124"(SH3 domain binding)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR032335|interpro:IPR032571|interpro:IPR036612|reactome:R-HSA-8849468|entrezgene/locuslink:202559(identity)	-	crc64:3CA920FA1204EC9C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:myPxXwP+mJgvoh50PLYk2Q3GMh4559292	rogid:IfFvZO2dIAo0Sdx+BUb5c8F7aQY9606	intact-crc:42A3455B5267AC04|rigid:f2MNvYVqYGJ5XmyCqWbdv28GSI0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96BA8	uniprotkb:P40533	intact:EBI-6942903|ensembl:ENSP00000481956|intact:MINT-268046|intact:MINT-8162577|uniprotkb:Q8N2D5|uniprotkb:Q96CP0	intact:EBI-24998|uniprotkb:D6VVP3|ensemblfungi:YIL039W	psi-mi:cr3l1_human(display_long)|uniprotkb:CREB3L1(gene name)|psi-mi:CREB3L1(display_short)|uniprotkb:OASIS(gene name synonym)|uniprotkb:PSEC0238(orf name)|uniprotkb:Old astrocyte specifically-induced substance(gene name synonym)	psi-mi:ted1_yeast(display_long)|uniprotkb:TED1(gene name)|psi-mi:TED1(display_short)|uniprotkb:Trafficking of EMP24/ERV25-dependent cargo disrupted protein 1(gene name synonym)|uniprotkb:YIL039W(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11531483|imex:IM-24995-958	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157613(gene)|ensembl:ENST00000621158(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0070278"(extracellular matrix constituent secretion)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029805|mint:Q96BA8|reactome:R-HSA-8874211|refseq:NP_443086.1|entrezgene/locuslink:90993(identity)	refseq:NP_012225.1|sgd:S000001301|mint:P40533|dip:DIP-4575N|ensemblfungi:YIL039W(gene)|ensemblfungi:YIL039W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006506"(GPI anchor biosynthetic process)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016787"(hydrolase activity)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR029052|interpro:IPR033307|interpro:IPR033308|sgd:YIL039W(identity)	-	comment:mint|function:"Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE"	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:sMWUFmBeBBCO+T0Y2CuB/un1lBg9606	rogid:/O/7xxWpFv7PwN+keOZRqQQPoFw559292	intact-crc:BCC5CA24651033DF|rigid:dPR79iA9fNxkT0y99IcuJJhC1RI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8N6L0	uniprotkb:P40533	intact:EBI-749265|uniprotkb:Q96MC3|ensembl:ENSP00000404220	intact:EBI-24998|uniprotkb:D6VVP3|ensemblfungi:YIL039W	psi-mi:kash5_human(display_long)|uniprotkb:KASH5(gene name)|psi-mi:KASH5(display_short)|uniprotkb:CCDC155(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 155(gene name synonym)|uniprotkb:KASH domain-containing protein 5(gene name synonym)	psi-mi:ted1_yeast(display_long)|uniprotkb:TED1(gene name)|psi-mi:TED1(display_short)|uniprotkb:Trafficking of EMP24/ERV25-dependent cargo disrupted protein 1(gene name synonym)|uniprotkb:YIL039W(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11531474|imex:IM-24995-957	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_653289.3|ensembl:ENSG00000161609(gene)|ensembl:ENST00000447857(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034397"(telomere localization)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051225"(spindle assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0090172"(microtubule cytoskeleton organization involved in homologous chromosome segregation)|go:"GO:0090220"(chromosome localization to nuclear envelope involved in homologous chromosome segregation)|go:"GO:0090619"(meiotic spindle pole)|interpro:IPR011992(EF-Hand type)|interpro:IPR028168|interpro:IPR028170|interpro:IPR039508|mint:Q8N6L0|rcsb pdb:6R2I|rcsb pdb:6WMF|entrezgene/locuslink:147872(identity)	refseq:NP_012225.1|sgd:S000001301|mint:P40533|dip:DIP-4575N|ensemblfungi:YIL039W(gene)|ensemblfungi:YIL039W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006506"(GPI anchor biosynthetic process)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016787"(hydrolase activity)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR029052|interpro:IPR033307|interpro:IPR033308|sgd:YIL039W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Wl9L7AcvDHCZuKjYLn8QgGIbZTc9606	rogid:/O/7xxWpFv7PwN+keOZRqQQPoFw559292	intact-crc:E67C1F962343FAB7|rigid:atuyt74ltwZk0Cp4nQBel7EZ7BE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40507	uniprotkb:Q96IK5	intact:EBI-25083|uniprotkb:D6VVK5|ensemblfungi:YIL079C	intact:EBI-2548508|ensembl:ENSP00000282570|uniprotkb:Q9H826|uniprotkb:Q9H8V7|uniprotkb:Q9H927	psi-mi:air1_yeast(display_long)|uniprotkb:Arginine methyltransferase-interacting RING finger protein 1(gene name synonym)|uniprotkb:AIR1(gene name)|psi-mi:AIR1(display_short)|uniprotkb:YIL079C(locus name)	psi-mi:gmcl1_human(display_long)|uniprotkb:GMCL1(gene name)|psi-mi:GMCL1(display_short)|uniprotkb:GCL(gene name synonym)|uniprotkb:BTBD13(gene name synonym)|uniprotkb:SPATA29(gene name synonym)|uniprotkb:Spermatogenesis-associated protein 29(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11531465|imex:IM-24995-956	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012186.1|sgd:S000001341|mint:P40507|dip:DIP-2700N|ensemblfungi:YIL079C(gene)|ensemblfungi:YIL079C_mRNA(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031499"(TRAMP complex)|go:"GO:0043629"(ncRNA polyadenylation)|go:"GO:0071031"(nuclear mRNA surveillance of mRNA 3'-end processing)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071036"(nuclear polyadenylation-dependent snoRNA catabolic process)|go:"GO:0071037"(nuclear polyadenylation-dependent snRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071039"(nuclear polyadenylation-dependent CUT catabolic process)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR016713("Poly(A) polymerase complex, Air1/2")|interpro:IPR036875|sgd:YIL079C(identity)	ensembl:ENSG00000087338(gene)|ensembl:ENST00000282570(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0007281"(germ cell development)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016363"(nuclear matrix)|go:"GO:0042802"(identical protein binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR043380|refseq:NP_848526.1|entrezgene/locuslink:64395(identity)	-	crc64:3CA920FA1204EC9C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:myPxXwP+mJgvoh50PLYk2Q3GMh4559292	rogid:ED8yqySVu7BWxpw3DUSNBZSQWrk9606	intact-crc:440578C7E9092512|rigid:vdWOOQGg2EmQkl9dneCG+ZkcJBk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8WV44	uniprotkb:P40507	intact:EBI-725997|uniprotkb:Q5BKT0|uniprotkb:Q7L484|uniprotkb:Q96Q10|intact:EBI-1551110|uniprotkb:Q9BSL8|uniprotkb:B3KNJ6|uniprotkb:D3DWR9|ensembl:ENSP00000320869	intact:EBI-25083|uniprotkb:D6VVK5|ensemblfungi:YIL079C	psi-mi:tri41_human(display_long)|uniprotkb:TRIM41(gene name)|psi-mi:TRIM41(display_short)|uniprotkb:RINCK(gene name synonym)|uniprotkb:Tripartite motif-containing protein 41(gene name synonym)|uniprotkb:RING finger-interacting protein with C kinase(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM41(gene name synonym)	psi-mi:air1_yeast(display_long)|uniprotkb:Arginine methyltransferase-interacting RING finger protein 1(gene name synonym)|uniprotkb:AIR1(gene name)|psi-mi:AIR1(display_short)|uniprotkb:YIL079C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11531454|imex:IM-24995-955	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_291027.3|refseq:NP_963921.1|ensembl:ENSG00000146063(gene)|ensembl:ENST00000315073(transcript)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0042802"(identical protein binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071225"(cellular response to muramyl dipeptide)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR042828|interpro:IPR043136|mint:Q8WV44|rcsb pdb:2EGM|reactome:R-HSA-983168|entrezgene/locuslink:90933(identity)	refseq:NP_012186.1|sgd:S000001341|mint:P40507|dip:DIP-2700N|ensemblfungi:YIL079C(gene)|ensemblfungi:YIL079C_mRNA(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031499"(TRAMP complex)|go:"GO:0043629"(ncRNA polyadenylation)|go:"GO:0071031"(nuclear mRNA surveillance of mRNA 3'-end processing)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071036"(nuclear polyadenylation-dependent snoRNA catabolic process)|go:"GO:0071037"(nuclear polyadenylation-dependent snRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071039"(nuclear polyadenylation-dependent CUT catabolic process)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR016713("Poly(A) polymerase complex, Air1/2")|interpro:IPR036875|sgd:YIL079C(identity)	-	-	crc64:3CA920FA1204EC9C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:BVqf0OHXPGsYe8F66mHzvD4XQ549606	rogid:myPxXwP+mJgvoh50PLYk2Q3GMh4559292	intact-crc:D5C550C43B6EB900|rigid:Yz4r4Nxyaosre+oy+CJRJxVqaRc	false	sufficient binding region:86-630	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P26641	uniprotkb:P40560	intact:EBI-351467|uniprotkb:Q6PJ62|uniprotkb:Q6PK31|uniprotkb:Q96CU2|uniprotkb:Q9P196|intact:EBI-2321928|uniprotkb:B4DTG2|ensembl:ENSP00000331901	intact:EBI-24911|uniprotkb:D6VVT0|ensemblfungi:YIL001W	psi-mi:ef1g_human(display_long)|uniprotkb:PRO1608(orf name)|uniprotkb:EEF1G(gene name)|psi-mi:EEF1G(display_short)|uniprotkb:EF1G(gene name synonym)|uniprotkb:eEF-1B gamma(gene name synonym)	psi-mi:yia1_yeast(display_long)|uniprotkb:YIA1W(orf name)|uniprotkb:YIL001W(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11531513|imex:IM-24995-961	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001395.1|ensembl:ENSG00000254772(gene)|ensembl:ENST00000329251(transcript)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006414"(translational elongation)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001662(Translation elongation factor EF1B, gamma chain, conserved)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR036249|interpro:IPR036282|interpro:IPR036433|interpro:IPR040079|mint:P26641|rcsb pdb:1PBU|rcsb pdb:5DQS|rcsb pdb:5JPO|reactome:R-HSA-156842|dip:DIP-32516N|entrezgene/locuslink:1937(identity)	sgd:S000001263|refseq:NP_012265.3|dip:DIP-1375N|ensemblfungi:YIL001W(gene)|ensemblfungi:YIL001W_mRNA(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0005737"(cytoplasm)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR036770|interpro:IPR044515|sgd:YIL001W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:biVN96umeEdPm/wvPN4VwbSRHTs9606	rogid:IOv6oxjYJ3W/jLnmIcM03RDQ8Ww559292	intact-crc:586CB7E6A1ADCF89|rigid:5DcFCkb5tofX9knZyCskKKL7DSI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8N5R6	uniprotkb:P40560	intact:EBI-740841|intact:EBI-953781|uniprotkb:B3KQ49|uniprotkb:A8K3U4|uniprotkb:A8MPQ6|uniprotkb:A8MV61|uniprotkb:A8MVU9|uniprotkb:Q9H5Q6|uniprotkb:Q8TAX6|intact:EBI-2320546|intact:EBI-11522976	intact:EBI-24911|uniprotkb:D6VVT0|ensemblfungi:YIL001W	psi-mi:ccd33_human(display_long)|uniprotkb:CCDC33(gene name)|psi-mi:CCDC33(display_short)|uniprotkb:Cancer/testis antigen 61(gene name synonym)	psi-mi:yia1_yeast(display_long)|uniprotkb:YIA1W(orf name)|uniprotkb:YIL001W(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11531504|imex:IM-24995-960	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_079331.3|interpro:IPR000008(C2 calcium-dependent membrane targeting)|go:"GO:0005777"(peroxisome)|refseq:NP_001274110.1|refseq:NP_877592.2|mint:Q8N5R6|interpro:IPR035892|interpro:IPR039889|entrezgene/locuslink:80125(identity)	sgd:S000001263|refseq:NP_012265.3|dip:DIP-1375N|ensemblfungi:YIL001W(gene)|ensemblfungi:YIL001W_mRNA(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0005737"(cytoplasm)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR036770|interpro:IPR044515|sgd:YIL001W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2021/11/30	rogid:eEIn7pQyfdHWx8TeLJpYy0i/gww9606	rogid:IOv6oxjYJ3W/jLnmIcM03RDQ8Ww559292	intact-crc:6687FD6769E3D004|rigid:pxGUZW0PhxoZskEkamFgZBgxPHE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40554	intact:EBI-11531492	intact:EBI-24940|uniprotkb:D6VVS2|ensemblfungi:YIL008W	-	psi-mi:urm1_yeast(display_long)|uniprotkb:YIL008W(locus name)|uniprotkb:URM1(gene name)|psi-mi:URM1(display_short)	psi-mi:znf3(display_short)|psi-mi:EBI-11531492(display_long)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11531495|imex:IM-24995-959	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000001270|refseq:NP_012258.3|dip:DIP-1894N|ensemblfungi:YIL008W(gene)|ensemblfungi:YIL008W_mRNA(transcript)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0002143"(tRNA wobble position uridine thiolation)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007114"(cell budding)|go:"GO:0031386"(protein tag)|go:"GO:0032447"(protein urmylation)|go:"GO:0034227"(tRNA thio-modification)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0097163"(sulfur carrier activity)|interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|interpro:IPR015221(Ubiquitin related modifier 1)|interpro:IPR016155(Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp)|rcsb pdb:2AX5|rcsb pdb:2PKO|rcsb pdb:2QJL|sgd:YIL008W(identity)	entrezgene/locuslink:7551(identity)	-	crc64:A15356D6C1B6B5BC	no-uniprot-update:	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:JFW+GAegUnn1FQ2++OlVr9IbgBA559292	rogid:eSPiEBOxNojLEOXLwp/UY9zTIwo9606	intact-crc:033C3FF882F03B35|rigid:YY/IMmZxhjIgmlUfYuA9YevnKM8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96B96	uniprotkb:P40581	intact:EBI-7055862|ensembl:ENSP00000233047|ensembl:ENSP00000261388|ensembl:ENSP00000460687|ensembl:ENSP00000492164|ensembl:ENSP00000492501|ensembl:ENSP00000491056|intact:MINT-8163962|intact:MINT-8201794|uniprotkb:A6NMA9|uniprotkb:O00323|uniprotkb:B4DEC1	intact:EBI-7869|ensemblfungi:YIR037W|uniprotkb:D6VVW8	psi-mi:ldaf1_human(display_long)|uniprotkb:LDAF1(gene name)|psi-mi:LDAF1(display_short)|uniprotkb:Promethin(gene name synonym)|uniprotkb:TMEM159(gene name synonym)|uniprotkb:Transmembrane protein 159(gene name synonym)	psi-mi:gpx3_yeast(display_long)|uniprotkb:HYR1(gene name)|psi-mi:HYR1(display_short)|uniprotkb:ORP1(gene name synonym)|uniprotkb:Hydrogen peroxide resistance protein 1(gene name synonym)|uniprotkb:Oxidant receptor peroxidase 1(gene name synonym)|uniprotkb:Phospholipid hydroperoxide glutathione peroxidase 3(gene name synonym)|uniprotkb:GPX3(gene name synonym)|uniprotkb:YIR037W(locus name)|uniprotkb:Glutathione peroxidase homolog 3(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11531540|imex:IM-24995-964	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001288698.1|refseq:NP_001288700.1|refseq:NP_001288702.1|refseq:NP_001288703.1|refseq:NP_001288704.1|ensembl:ENSG00000011638(gene)|ensembl:ENSG00000283997(gene)|ensembl:ENST00000233047(transcript)|ensembl:ENST00000261388(transcript)|ensembl:ENST00000572599(transcript)|ensembl:ENST00000638934(transcript)|ensembl:ENST00000640188(transcript)|ensembl:ENST00000640514(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0016021"(integral component of membrane)|go:"GO:0140042"(lipid droplet formation)|interpro:IPR029709|mint:Q96B96|refseq:NP_065155.3|refseq:XP_005255496.1|refseq:XP_006721129.1|entrezgene/locuslink:57146(identity)	refseq:NP_012303.1|sgd:S000001476|ensemblfungi:YIR037W(gene)|ensemblfungi:YIR037W_mRNA(transcript)|go:"GO:0004601"(peroxidase activity)|go:"GO:0004602"(glutathione peroxidase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005829"(cytosol)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0047066"(phospholipid-hydroperoxide glutathione peroxidase activity)|go:"GO:0051920"(peroxiredoxin activity)|interpro:IPR000889(Glutathione peroxidase)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR029760|interpro:IPR036249|rcsb pdb:3CMI|reactome:R-SCE-2142712|reactome:R-SCE-9018676|reactome:R-SCE-9018896|reactome:R-SCE-9020265|reactome:R-SCE-9023661|interpro:IPR029759|mint:P40581|dip:DIP-1275N|sgd:YIR037W(identity)	-	comment:mint	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:qDMjn8OVxY8eRUFJTc8hxD3Tk0c9606	rogid:Pi8aaZEVc33CTMPyaM0mpscvLU4559292	intact-crc:5BDB9F9E9F5F516A|rigid:mgnY5oY9Y6iSPiFRmMFG4UvDHng	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8N6L0	uniprotkb:P40567	intact:EBI-749265|uniprotkb:Q96MC3|ensembl:ENSP00000404220	intact:EBI-789|uniprotkb:D6VVT9|ensemblfungi:YIR009W	psi-mi:kash5_human(display_long)|uniprotkb:KASH5(gene name)|psi-mi:KASH5(display_short)|uniprotkb:CCDC155(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 155(gene name synonym)|uniprotkb:KASH domain-containing protein 5(gene name synonym)	psi-mi:msl1_yeast(display_long)|uniprotkb:YIB9W(orf name)|uniprotkb:YIR009W(locus name)|uniprotkb:MSL1(gene name)|psi-mi:MSL1(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11531531|imex:IM-24995-963	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_653289.3|ensembl:ENSG00000161609(gene)|ensembl:ENST00000447857(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034397"(telomere localization)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051225"(spindle assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0090172"(microtubule cytoskeleton organization involved in homologous chromosome segregation)|go:"GO:0090220"(chromosome localization to nuclear envelope involved in homologous chromosome segregation)|go:"GO:0090619"(meiotic spindle pole)|interpro:IPR011992(EF-Hand type)|interpro:IPR028168|interpro:IPR028170|interpro:IPR039508|mint:Q8N6L0|rcsb pdb:6R2I|rcsb pdb:6WMF|entrezgene/locuslink:147872(identity)	refseq:NP_012274.1|sgd:S000001448|rcsb pdb:6BK8|ensemblfungi:YIR009W(gene)|ensemblfungi:YIR009W_mRNA(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005685"(U1 snRNP)|go:"GO:0030619"(U1 snRNA binding)|go:"GO:0030620"(U2 snRNA binding)|go:"GO:0071004"(U2-type prespliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5MQ0|rcsb pdb:5NRL|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:5ZWM|rcsb pdb:5ZWO|dip:DIP-816N|mint:P40567|rcsb pdb:6EXN|rcsb pdb:6G90|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|sgd:YIR009W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Wl9L7AcvDHCZuKjYLn8QgGIbZTc9606	rogid:GAiHZKcbfNjbem3+i1cZXFm4NfE559292	intact-crc:F0DCDC8582A4300E|rigid:n1Ez7t+dqoZQpQT8zY35xI/j6uY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P56279	uniprotkb:P40560	intact:EBI-749995|uniprotkb:Q6IBK7|ensembl:ENSP00000385036|ensembl:ENSP00000450496|ensembl:ENSP00000450701|ensembl:ENSP00000451506	intact:EBI-24911|uniprotkb:D6VVT0|ensemblfungi:YIL001W	psi-mi:tcl1a_human(display_long)|uniprotkb:Protein p14 TCL1(gene name synonym)|uniprotkb:Oncogene TCL-1(gene name synonym)|uniprotkb:TCL1A(gene name)|psi-mi:TCL1A(display_short)|uniprotkb:TCL1(gene name synonym)	psi-mi:yia1_yeast(display_long)|uniprotkb:YIA1W(orf name)|uniprotkb:YIL001W(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11531522|imex:IM-24995-962	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001092195.1|refseq:NP_068801.1|refseq:XP_016877165.1|refseq:XP_016877166.1|dip:DIP-60787N|ensembl:ENSG00000100721(gene)|ensembl:ENST00000402399(transcript)|ensembl:ENST00000554012(transcript)|ensembl:ENST00000555202(transcript)|ensembl:ENST00000556450(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010918"(positive regulation of mitochondrial membrane potential)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|interpro:IPR004832(TCL1/MTCP1)|interpro:IPR036672|rcsb pdb:1JSG|entrezgene/locuslink:8115(identity)	sgd:S000001263|refseq:NP_012265.3|dip:DIP-1375N|ensemblfungi:YIL001W(gene)|ensemblfungi:YIL001W_mRNA(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0005737"(cytoplasm)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR036770|interpro:IPR044515|sgd:YIL001W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:c3GIYkYNb+wWlxn59oU2vpvbfhI9606	rogid:IOv6oxjYJ3W/jLnmIcM03RDQ8Ww559292	intact-crc:45A68FFEA8E040E3|rigid:QdJLKH/PLO6O2Zc3fR0ilnWuV+8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:A0A0A0MQZ8	uniprotkb:P40956	intact:EBI-11531560|ensembl:ENSP00000297183	intact:EBI-7968|uniprotkb:D6VTX2|ensemblfungi:YGL181W	psi-mi:a0a0a0mqz8_human(display_long)|uniprotkb:ANKHD1(gene name)|psi-mi:ANKHD1(display_short)	psi-mi:gts1_yeast(display_long)|uniprotkb:YGL181W(locus name)|uniprotkb:GTS1(gene name)|psi-mi:GTS1(display_short)|uniprotkb:LSR1(gene name synonym)|uniprotkb:Protein LSR1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11531558|imex:IM-24995-966	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000131503(gene)|ensembl:ENST00000297183(transcript)|go:"GO:0003723"(RNA binding)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR036612|entrezgene/locuslink:54882(identity)	refseq:NP_011334.1|sgd:S000003149|mint:P40956|dip:DIP-2746N|ensemblfungi:YGL181W(gene)|ensemblfungi:YGL181W_mRNA(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0006897"(endocytosis)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010512"(negative regulation of phosphatidylinositol biosynthetic process)|go:"GO:0030479"(actin cortical patch)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR037278|interpro:IPR038508|sgd:YGL181W(identity)	-	-	crc64:D687E3BF6B620795	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:o5PbZ86LdldDZqy6ao7ukLpABbE9606	rogid:8kgpssCRrHiTHsFaOH2nDK6EIjk559292	intact-crc:914E675C70702782|rigid:/22GAeVY0E/rn992a9sDkg20l8w	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96BA8	uniprotkb:P40857	intact:EBI-6942903|ensembl:ENSP00000481956|intact:MINT-268046|intact:MINT-8162577|uniprotkb:Q8N2D5|uniprotkb:Q96CP0	intact:EBI-26003|uniprotkb:D6VW87|ensemblfungi:YJL097W	psi-mi:cr3l1_human(display_long)|uniprotkb:CREB3L1(gene name)|psi-mi:CREB3L1(display_short)|uniprotkb:OASIS(gene name synonym)|uniprotkb:PSEC0238(orf name)|uniprotkb:Old astrocyte specifically-induced substance(gene name synonym)	psi-mi:hacd_yeast(display_long)|uniprotkb:YJL097W(locus name)|uniprotkb:J0902(orf name)|uniprotkb:PTPLA homolog involved in sphingolipid biosynthesis protein 1(gene name synonym)|uniprotkb:PHS1(gene name)|psi-mi:PHS1(display_short)|uniprotkb:3-hydroxyacyl-CoA dehydratase PHS1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11531549|imex:IM-24995-965	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157613(gene)|ensembl:ENST00000621158(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0070278"(extracellular matrix constituent secretion)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029805|mint:Q96BA8|reactome:R-HSA-8874211|refseq:NP_443086.1|entrezgene/locuslink:90993(identity)	refseq:NP_012438.1|sgd:S000003633|reactome:R-SCE-75876|dip:DIP-2104N|ensemblfungi:YJL097W(gene)|ensemblfungi:YJL097W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0004300"(enoyl-CoA hydratase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0042175"(nuclear outer membrane-endoplasmic reticulum membrane network)|go:"GO:0042761"(very long-chain fatty acid biosynthetic process)|go:"GO:0102158"(very-long-chain 3-hydroxyacyl-CoA dehydratase activity)|go:"GO:0102343"(3-hydroxy-arachidoyl-CoA dehydratase activity)|go:"GO:0102344"(3-hydroxy-behenoyl-CoA dehydratase activity)|go:"GO:0102345"(3-hydroxy-lignoceroyl-CoA dehydratase activity)|interpro:IPR007482(Protein-tyrosine phosphatase-like, PTPLA)|go:"GO:0007034"(vacuolar transport)|go:"GO:0018812"(3-hydroxyacyl-CoA dehydratase activity)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030497"(fatty acid elongation)|sgd:YJL097W(identity)	-	comment:mint|function:"Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE"	crc64:5C87BC9563FB83AA	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:sMWUFmBeBBCO+T0Y2CuB/un1lBg9606	rogid:4C/5U50EeqZ6OR+MR8zFHLo36s8559292	intact-crc:6FF963CBAC6A575A|rigid:hgunBsGSYaLR369OyA9xNP3usLI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P23511-2	uniprotkb:P40956	intact:EBI-11061759|ensembl:ENSP00000229418	intact:EBI-7968|uniprotkb:D6VTX2|ensemblfungi:YGL181W	psi-mi:p23511-2(display_long)|uniprotkb:NFYA(gene name)|psi-mi:NFYA(display_short)|uniprotkb:CAAT box DNA-binding protein subunit A(gene name synonym)|uniprotkb:Nuclear transcription factor Y subunit A(gene name synonym)	psi-mi:gts1_yeast(display_long)|uniprotkb:YGL181W(locus name)|uniprotkb:GTS1(gene name)|psi-mi:GTS1(display_short)|uniprotkb:LSR1(gene name synonym)|uniprotkb:Protein LSR1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11531602|imex:IM-24995-970	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-389739(isoform-parent)|ensembl:ENSG00000001167(gene)|ensembl:ENST00000353205(transcript)|uniprotkb:P23511-2(isoform-parent)|entrezgene/locuslink:4800(identity)	refseq:NP_011334.1|sgd:S000003149|mint:P40956|dip:DIP-2746N|ensemblfungi:YGL181W(gene)|ensemblfungi:YGL181W_mRNA(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0006897"(endocytosis)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010512"(negative regulation of phosphatidylinositol biosynthetic process)|go:"GO:0030479"(actin cortical patch)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR037278|interpro:IPR038508|sgd:YGL181W(identity)	-	-	crc64:D687E3BF6B620795	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:9IOUoaGszX6kd9hzrCj6BBkgJ+09606	rogid:8kgpssCRrHiTHsFaOH2nDK6EIjk559292	intact-crc:50112468887B04E5|rigid:71UqtccFw4nTapWPLP3j01Da15k	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O43251-3	uniprotkb:P40956	intact:EBI-11531589|ensembl:ENSP00000262829|ensembl:ENSP00000485711	intact:EBI-7968|uniprotkb:D6VTX2|ensemblfungi:YGL181W	psi-mi:o43251-3(display_long)|uniprotkb:RBFOX2(gene name)|psi-mi:RBFOX2(display_short)|uniprotkb:FOX2(gene name synonym)|uniprotkb:Fox-1 homolog B(gene name synonym)|uniprotkb:HRNBP2(gene name synonym)|uniprotkb:Hexaribonucleotide-binding protein 2(gene name synonym)|uniprotkb:RBM9(gene name synonym)|uniprotkb:RNA-binding motif protein 9(gene name synonym)|uniprotkb:RNA-binding protein 9(gene name synonym)|uniprotkb:RTA(gene name synonym)|uniprotkb:Repressor of tamoxifen transcriptional activity(gene name synonym)	psi-mi:gts1_yeast(display_long)|uniprotkb:YGL181W(locus name)|uniprotkb:GTS1(gene name)|psi-mi:GTS1(display_short)|uniprotkb:LSR1(gene name synonym)|uniprotkb:Protein LSR1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11531593|imex:IM-24995-969	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-746056(isoform-parent)|ensembl:ENSG00000100320(gene)|ensembl:ENSG00000277564(gene)|ensembl:ENST00000262829(transcript)|ensembl:ENST00000631365(transcript)|uniprotkb:O43251-3(isoform-parent)|entrezgene/locuslink:23543(identity)	refseq:NP_011334.1|sgd:S000003149|mint:P40956|dip:DIP-2746N|ensemblfungi:YGL181W(gene)|ensemblfungi:YGL181W_mRNA(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0006897"(endocytosis)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010512"(negative regulation of phosphatidylinositol biosynthetic process)|go:"GO:0030479"(actin cortical patch)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR037278|interpro:IPR038508|sgd:YGL181W(identity)	-	isoform-comment:No experimental confirmation available. Contains a omega-N-methylarginine at position 249.	crc64:D687E3BF6B620795	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:NFXIvVJoroP1SezcZfQYKHTlTR09606	rogid:8kgpssCRrHiTHsFaOH2nDK6EIjk559292	intact-crc:EAC45BCDD69638BB|rigid:D7Jga27uEEhBeK+L+m1yop8Wfsk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O43186	uniprotkb:P40956	intact:EBI-748171|uniprotkb:Q0QD45|ensembl:ENSP00000221996|ensembl:ENSP00000445565	intact:EBI-7968|uniprotkb:D6VTX2|ensemblfungi:YGL181W	psi-mi:crx_human(display_long)|uniprotkb:CRX(gene name)|psi-mi:CRX(display_short)|uniprotkb:CORD2(gene name synonym)	psi-mi:gts1_yeast(display_long)|uniprotkb:YGL181W(locus name)|uniprotkb:GTS1(gene name)|psi-mi:GTS1(display_short)|uniprotkb:LSR1(gene name synonym)|uniprotkb:Protein LSR1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11531580|imex:IM-24995-968	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000545.1|ensembl:ENSG00000105392(gene)|ensembl:ENST00000221996(transcript)|ensembl:ENST00000539067(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007601"(visual perception)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050896"(response to stimulus)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013851(Transcription factor Otx, C-terminal)|interpro:IPR017970|entrezgene/locuslink:1406(identity)	refseq:NP_011334.1|sgd:S000003149|mint:P40956|dip:DIP-2746N|ensemblfungi:YGL181W(gene)|ensemblfungi:YGL181W_mRNA(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0006897"(endocytosis)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010512"(negative regulation of phosphatidylinositol biosynthetic process)|go:"GO:0030479"(actin cortical patch)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR037278|interpro:IPR038508|sgd:YGL181W(identity)	-	-	crc64:D687E3BF6B620795	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:v/bkO/0iLzq1Q2HtieWQQ40RF9M9606	rogid:8kgpssCRrHiTHsFaOH2nDK6EIjk559292	intact-crc:8133A8446AED6620|rigid:G2P8FEYVyuPKDDMlW1xHCR97OT8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O14641	uniprotkb:P40956	intact:EBI-740850|ensembl:ENSP00000005340|uniprotkb:Q53XM0|uniprotkb:D3DTN3	intact:EBI-7968|uniprotkb:D6VTX2|ensemblfungi:YGL181W	psi-mi:dvl2_human(display_long)|uniprotkb:DSH homolog 2(gene name synonym)|uniprotkb:DVL2(gene name)|psi-mi:DVL2(display_short)	psi-mi:gts1_yeast(display_long)|uniprotkb:YGL181W(locus name)|uniprotkb:GTS1(gene name)|psi-mi:GTS1(display_short)|uniprotkb:LSR1(gene name synonym)|uniprotkb:Protein LSR1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11531571|imex:IM-24995-967	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004413.1|ensembl:ENSG00000004975(gene)|ensembl:ENST00000005340(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005109"(frizzled binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0007507"(heart development)|go:"GO:0016235"(aggresome)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044340"(canonical Wnt signaling pathway involved in regulation of cell proliferation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0150012"(positive regulation of neuron projection arborization)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008341(Dishevelled-2 region)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:O14641|rcsb pdb:2REY|rcsb pdb:3CBX|rcsb pdb:3CBY|rcsb pdb:3CBZ|rcsb pdb:3CC0|rcsb pdb:4WIP|rcsb pdb:5LNP|rcsb pdb:5SUY|rcsb pdb:5SUZ|rcsb pdb:6IW3|rcsb pdb:6JCK|reactome:R-HSA-201681|reactome:R-HSA-201688|reactome:R-HSA-2028269|reactome:R-HSA-4086400|reactome:R-HSA-4608870|reactome:R-HSA-4641258|reactome:R-HSA-4641262|reactome:R-HSA-5099900|reactome:R-HSA-5368598|reactome:R-HSA-5663220|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9673324|ensembl:ENSP00000005340|dip:DIP-34433N|entrezgene/locuslink:1856(identity)	refseq:NP_011334.1|sgd:S000003149|mint:P40956|dip:DIP-2746N|ensemblfungi:YGL181W(gene)|ensemblfungi:YGL181W_mRNA(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0006897"(endocytosis)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010512"(negative regulation of phosphatidylinositol biosynthetic process)|go:"GO:0030479"(actin cortical patch)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR037278|interpro:IPR038508|sgd:YGL181W(identity)	-	-	crc64:D687E3BF6B620795	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:2Vdc8oRnT4Mz/j+EXQXrL3AszOc9606	rogid:8kgpssCRrHiTHsFaOH2nDK6EIjk559292	intact-crc:9E2DFD469262BD5F|rigid:f+XqEw2aghQg19Q6AH+2v3F0+68	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40956	uniprotkb:Q6P1W5	intact:EBI-7968|uniprotkb:D6VTX2|ensemblfungi:YGL181W	intact:EBI-946029|uniprotkb:B3KVT1|uniprotkb:Q96IC8|ensembl:ENSP00000435634|uniprotkb:D3DPR3|uniprotkb:E9PJ76	psi-mi:gts1_yeast(display_long)|uniprotkb:YGL181W(locus name)|uniprotkb:GTS1(gene name)|psi-mi:GTS1(display_short)|uniprotkb:LSR1(gene name synonym)|uniprotkb:Protein LSR1(gene name synonym)	psi-mi:ca094_human(display_long)|uniprotkb:C1orf94(gene name)|psi-mi:C1orf94(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11531629|imex:IM-24995-973	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011334.1|sgd:S000003149|mint:P40956|dip:DIP-2746N|ensemblfungi:YGL181W(gene)|ensemblfungi:YGL181W_mRNA(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0006897"(endocytosis)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010512"(negative regulation of phosphatidylinositol biosynthetic process)|go:"GO:0030479"(actin cortical patch)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR037278|interpro:IPR038508|sgd:YGL181W(identity)	refseq:NP_001128206.1|refseq:NP_116273.2|ensembl:ENSG00000142698(gene)|ensembl:ENST00000488417(transcript)|interpro:IPR031496|entrezgene/locuslink:84970(identity)	-	crc64:D687E3BF6B620795	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:8kgpssCRrHiTHsFaOH2nDK6EIjk559292	rogid:y1o4xWvTl2CBA1J7jsP7y8ZjLzM9606	intact-crc:C81EDEB8E315F84A|rigid:2rsxj/TugFNarklH///ujv8mEKg	false	-	sufficient binding region:191-598	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q15038	uniprotkb:P40956	intact:EBI-724310|ensembl:ENSP00000394699|uniprotkb:E9PB45|uniprotkb:A8K254|uniprotkb:B4DDT5|uniprotkb:C9JA96|uniprotkb:C9JP84|uniprotkb:B4E1G3|uniprotkb:F8VU62	intact:EBI-7968|uniprotkb:D6VTX2|ensemblfungi:YGL181W	psi-mi:dazp2_human(display_long)|uniprotkb:Deleted in azoospermia-associated protein 2(gene name synonym)|uniprotkb:DAZAP2(gene name)|psi-mi:DAZAP2(display_short)|uniprotkb:KIAA0058(gene name synonym)	psi-mi:gts1_yeast(display_long)|uniprotkb:YGL181W(locus name)|uniprotkb:GTS1(gene name)|psi-mi:GTS1(display_short)|uniprotkb:LSR1(gene name synonym)|uniprotkb:Protein LSR1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11531620|imex:IM-24995-972	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000183283(gene)|ensembl:ENST00000412716(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0016607"(nuclear speck)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0050699"(WW domain binding)|interpro:IPR022730|mint:Q15038|refseq:NP_001129736.1|refseq:NP_055579.1|ensembl:ENSP00000394699|ensembl:ENST00000425012|ensembl:ENSP00000408251|ensembl:ENST00000439799|ensembl:ENSP00000398804|ensembl:ENST00000449723|ensembl:ENSP00000412812|ensembl:ENST00000549555|ensembl:ENSP00000448051|ensembl:ENST00000549732|ensembl:ENSP00000446554|refseq:NP_001129741.1|refseq:NP_001129739.1|refseq:NP_001129740.1|refseq:NP_001129738.1|entrezgene/locuslink:9802(identity)	refseq:NP_011334.1|sgd:S000003149|mint:P40956|dip:DIP-2746N|ensemblfungi:YGL181W(gene)|ensemblfungi:YGL181W_mRNA(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0006897"(endocytosis)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010512"(negative regulation of phosphatidylinositol biosynthetic process)|go:"GO:0030479"(actin cortical patch)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR037278|interpro:IPR038508|sgd:YGL181W(identity)	-	-	crc64:D687E3BF6B620795	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:ASRqCZBG4q1U/y95PUSMKsgfm/g9606	rogid:8kgpssCRrHiTHsFaOH2nDK6EIjk559292	intact-crc:42CBC5A0183BA51A|rigid:tq/jX7xeiamy1eGRo5l6cuOWtgU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40956	uniprotkb:P63279	intact:EBI-7968|uniprotkb:D6VTX2|ensemblfungi:YGL181W	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	psi-mi:gts1_yeast(display_long)|uniprotkb:YGL181W(locus name)|uniprotkb:GTS1(gene name)|psi-mi:GTS1(display_short)|uniprotkb:LSR1(gene name synonym)|uniprotkb:Protein LSR1(gene name synonym)	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11531611|imex:IM-24995-971	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011334.1|sgd:S000003149|mint:P40956|dip:DIP-2746N|ensemblfungi:YGL181W(gene)|ensemblfungi:YGL181W_mRNA(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0006897"(endocytosis)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010512"(negative regulation of phosphatidylinositol biosynthetic process)|go:"GO:0030479"(actin cortical patch)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR037278|interpro:IPR038508|sgd:YGL181W(identity)	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N|entrezgene/locuslink:7329(identity)	-	crc64:D687E3BF6B620795	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:8kgpssCRrHiTHsFaOH2nDK6EIjk559292	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	intact-crc:363AA1162705BCD0|rigid:wtK95pRnYCE8bf/gF5tg06A8uk8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40956	uniprotkb:Q93062-3	intact:EBI-7968|uniprotkb:D6VTX2|ensemblfungi:YGL181W	intact:EBI-740343|ensembl:ENSP00000340176	psi-mi:gts1_yeast(display_long)|uniprotkb:YGL181W(locus name)|uniprotkb:GTS1(gene name)|psi-mi:GTS1(display_short)|uniprotkb:LSR1(gene name synonym)|uniprotkb:Protein LSR1(gene name synonym)	psi-mi:q93062-3(display_long)|uniprotkb:RBPMS(gene name)|psi-mi:RBPMS(display_short)|uniprotkb:HERMES(gene name synonym)|uniprotkb:Heart and RRM expressed sequence(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11531660|imex:IM-24995-976	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011334.1|sgd:S000003149|mint:P40956|dip:DIP-2746N|ensemblfungi:YGL181W(gene)|ensemblfungi:YGL181W_mRNA(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0006897"(endocytosis)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010512"(negative regulation of phosphatidylinositol biosynthetic process)|go:"GO:0030479"(actin cortical patch)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR037278|interpro:IPR038508|sgd:YGL181W(identity)	intact:EBI-740322(rbpms_human)|uniprotkb:Q93062-3(isoform-parent)|ensembl:ENSG00000157110(gene)|ensembl:ENST00000339877(transcript)|entrezgene/locuslink:11030(identity)	-	crc64:D687E3BF6B620795	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:8kgpssCRrHiTHsFaOH2nDK6EIjk559292	rogid:nlPMQAJoKEbPYBwsL3xodmCKd7c9606	intact-crc:3FA84CC3AED570D3|rigid:l+njoww6eYylGUddB6RVXgcNerY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40956	uniprotkb:Q92734	intact:EBI-7968|uniprotkb:D6VTX2|ensemblfungi:YGL181W	intact:EBI-357061|uniprotkb:Q15656|intact:EBI-357314|uniprotkb:Q969I2|uniprotkb:D3DN49|uniprotkb:K0J5S8|uniprotkb:K0J6K2|intact:EBI-28969365|ensembl:ENSP00000240851|ensembl:ENSP00000419960|ensembl:ENSP00000420797|ensembl:ENSP00000501815|ensembl:ENSP00000502071|ensembl:ENSP00000502450|ensembl:ENSP00000502592|ensembl:ENSP00000502734|uniprotkb:G5E9V1	psi-mi:gts1_yeast(display_long)|uniprotkb:YGL181W(locus name)|uniprotkb:GTS1(gene name)|psi-mi:GTS1(display_short)|uniprotkb:LSR1(gene name synonym)|uniprotkb:Protein LSR1(gene name synonym)	psi-mi:tfg_human(display_long)|uniprotkb:TFG(gene name)|psi-mi:TFG(display_short)|uniprotkb:TRK-fused gene protein(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11531651|imex:IM-24995-975	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011334.1|sgd:S000003149|mint:P40956|dip:DIP-2746N|ensemblfungi:YGL181W(gene)|ensemblfungi:YGL181W_mRNA(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0006897"(endocytosis)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010512"(negative regulation of phosphatidylinositol biosynthetic process)|go:"GO:0030479"(actin cortical patch)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR037278|interpro:IPR038508|sgd:YGL181W(identity)	refseq:NP_001007566.1|refseq:NP_001182407.1|refseq:NP_001182408.1|refseq:NP_006061.2|ensembl:ENSP00000240851|ensembl:ENST00000463568|ensembl:ENSP00000419504|ensembl:ENST00000476228|ensembl:ENSP00000417952|ensembl:ENSP00000420797|ensembl:ENSP00000419960|ensembl:ENST00000615993|ensembl:ENSP00000479269|ensembl:ENST00000620299|ensembl:ENSP00000479981|ensembl:ENSP00000502734|ensembl:ENST00000674645|ensembl:ENSP00000501892|ensembl:ENST00000674758|ensembl:ENSP00000502502|ensembl:ENST00000675047|ensembl:ENSP00000502497|ensembl:ENSP00000502592|ensembl:ENST00000675420|ensembl:ENSP00000502516|ensembl:ENSP00000502450|ensembl:ENST00000675543|ensembl:ENSP00000501815|ensembl:ENST00000675586|ensembl:ENSP00000502329|ensembl:ENST00000676111|ensembl:ENSP00000502139|ensembl:ENST00000676308|ensembl:ENSP00000502697|ensembl:ENSP00000502071|ensembl:ENST00000676431|ensembl:ENSP00000502698|ensembl:ENSP00000502229|refseq:XP_006713535.1|refseq:XP_006713536.1|ensembl:ENSG00000114354(gene)|ensembl:ENST00000240851(transcript)|ensembl:ENST00000487505(transcript)|ensembl:ENST00000490574(transcript)|ensembl:ENST00000674615(transcript)|ensembl:ENST00000675243(transcript)|ensembl:ENST00000675499(transcript)|ensembl:ENST00000675553(transcript)|ensembl:ENST00000676395(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048208"(COPII vesicle coating)|go:"GO:0070971"(endoplasmic reticulum exit site)|interpro:IPR000270(Octicosapeptide/Phox/Bem1p)|interpro:IPR033512|interpro:IPR034857|mint:Q92734|reactome:R-HSA-204005|refseq:XP_011510636.1|refseq:XP_005247123.1|refseq:XP_016861016.1|refseq:XP_016861017.1|refseq:XP_016861018.1|refseq:XP_016861019.1|entrezgene/locuslink:10342(identity)	-	crc64:D687E3BF6B620795	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:8kgpssCRrHiTHsFaOH2nDK6EIjk559292	rogid:y7aghh0X3Ewgpzcx5h5nB+X2dII9606	intact-crc:BC6D76A2A96F7260|rigid:/k+kbKNm/+JBeWuHk0bYBxyr74M	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40956	uniprotkb:Q8N684-3	intact:EBI-7968|uniprotkb:D6VTX2|ensemblfungi:YGL181W	intact:EBI-11523759|ensembl:ENSP00000345412	psi-mi:gts1_yeast(display_long)|uniprotkb:YGL181W(locus name)|uniprotkb:GTS1(gene name)|psi-mi:GTS1(display_short)|uniprotkb:LSR1(gene name synonym)|uniprotkb:Protein LSR1(gene name synonym)	psi-mi:q8n684-3(display_long)|uniprotkb:Cleavage factor Im complex 59 kDa subunit(gene name synonym)|uniprotkb:CPSF7(gene name)|psi-mi:CPSF7(display_short)|uniprotkb:Cleavage and polyadenylation specificity factor 59 kDa subunit(gene name synonym)|uniprotkb:Pre-mRNA cleavage factor Im 59 kDa subunit(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11531640|imex:IM-24995-974	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011334.1|sgd:S000003149|mint:P40956|dip:DIP-2746N|ensemblfungi:YGL181W(gene)|ensemblfungi:YGL181W_mRNA(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0006897"(endocytosis)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010512"(negative regulation of phosphatidylinositol biosynthetic process)|go:"GO:0030479"(actin cortical patch)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR037278|interpro:IPR038508|sgd:YGL181W(identity)	intact:EBI-746909(isoform-parent)|ensembl:ENSG00000149532(gene)|ensembl:ENST00000340437(transcript)|uniprotkb:Q8N684-3(isoform-parent)|entrezgene/locuslink:79869(identity)	-	crc64:D687E3BF6B620795	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:8kgpssCRrHiTHsFaOH2nDK6EIjk559292	rogid:hnk6o9HBKsdIRWKRuEdjdByVKxM9606	intact-crc:C49BC91AF46BBF26|rigid:vh7qvcU5v39+DjimLgDnPocm+bE	false	-	sufficient binding region:44-514	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40956	uniprotkb:Q9NP66	intact:EBI-7968|uniprotkb:D6VTX2|ensemblfungi:YGL181W	intact:EBI-740641|ensembl:ENSP00000336856|ensembl:ENSP00000371133|uniprotkb:A6NHY3|uniprotkb:Q53G31|uniprotkb:Q9NSF6|uniprotkb:D3DW78	psi-mi:gts1_yeast(display_long)|uniprotkb:YGL181W(locus name)|uniprotkb:GTS1(gene name)|psi-mi:GTS1(display_short)|uniprotkb:LSR1(gene name synonym)|uniprotkb:Protein LSR1(gene name synonym)	psi-mi:hm20a_human(display_long)|uniprotkb:HMG box-containing protein 20A(gene name synonym)|uniprotkb:HMG domain-containing protein HMGX1(gene name synonym)|uniprotkb:HMG20A(gene name)|psi-mi:HMG20A(display_short)|uniprotkb:HMGX1(gene name synonym)|uniprotkb:HMGXB1(gene name synonym)|uniprotkb:HMG domain-containing protein 1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11531689|imex:IM-24995-979	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011334.1|sgd:S000003149|mint:P40956|dip:DIP-2746N|ensemblfungi:YGL181W(gene)|ensemblfungi:YGL181W_mRNA(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0006897"(endocytosis)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010512"(negative regulation of phosphatidylinositol biosynthetic process)|go:"GO:0030479"(actin cortical patch)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR037278|interpro:IPR038508|sgd:YGL181W(identity)	refseq:NP_060670.1|ensembl:ENSG00000140382(gene)|ensembl:ENST00000336216(transcript)|ensembl:ENST00000381714(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0033234"(negative regulation of protein sumoylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045665"(negative regulation of neuron differentiation)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR036910|mint:Q9NP66|refseq:NP_001291433.1|refseq:NP_001291434.1|refseq:XP_011519460.1|entrezgene/locuslink:10363(identity)	-	crc64:D687E3BF6B620795	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:8kgpssCRrHiTHsFaOH2nDK6EIjk559292	rogid:LhilayeP+xv97pbYzIA8yMvwUbc9606	intact-crc:6D5781D3DFAD10CC|rigid:KFGEdcORXXfJ143rC9druKM9Cf8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9BQY4	uniprotkb:P40956	intact:EBI-372094|uniprotkb:Q9BR00|ensembl:ENSP00000360441	intact:EBI-7968|uniprotkb:D6VTX2|ensemblfungi:YGL181W	psi-mi:rhxf2_human(display_long)|uniprotkb:RHOXF2(gene name)|psi-mi:RHOXF2(display_short)|uniprotkb:THG1(gene name synonym)|uniprotkb:Paired-like homeobox protein PEPP-2(gene name synonym)|uniprotkb:Testis homeobox gene 1(gene name synonym)|uniprotkb:PEPP2(gene name synonym)	psi-mi:gts1_yeast(display_long)|uniprotkb:YGL181W(locus name)|uniprotkb:GTS1(gene name)|psi-mi:GTS1(display_short)|uniprotkb:LSR1(gene name synonym)|uniprotkb:Protein LSR1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11531680|imex:IM-24995-978	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_115887.1|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0042802"(identical protein binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|ensembl:ENSG00000131721(gene)|ensembl:ENST00000371388(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|entrezgene/locuslink:84528(identity)	refseq:NP_011334.1|sgd:S000003149|mint:P40956|dip:DIP-2746N|ensemblfungi:YGL181W(gene)|ensemblfungi:YGL181W_mRNA(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0006897"(endocytosis)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010512"(negative regulation of phosphatidylinositol biosynthetic process)|go:"GO:0030479"(actin cortical patch)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR037278|interpro:IPR038508|sgd:YGL181W(identity)	-	-	crc64:D687E3BF6B620795	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:shpgPqf80gNt+gFDv1K+827ELUQ9606	rogid:8kgpssCRrHiTHsFaOH2nDK6EIjk559292	intact-crc:4784E2B1CC5EDD89|rigid:RFaTOGL6SABsauK/jjDGC+NhWAY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40956	uniprotkb:Q96MA1	intact:EBI-7968|uniprotkb:D6VTX2|ensemblfungi:YGL181W	intact:EBI-954466|uniprotkb:Q96SD2|ensembl:ENSP00000360500	psi-mi:gts1_yeast(display_long)|uniprotkb:YGL181W(locus name)|uniprotkb:GTS1(gene name)|psi-mi:GTS1(display_short)|uniprotkb:LSR1(gene name synonym)|uniprotkb:Protein LSR1(gene name synonym)	psi-mi:dmrtb_human(display_long)|uniprotkb:DMRTB1(gene name)|psi-mi:DMRTB1(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11531669|imex:IM-24995-977	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011334.1|sgd:S000003149|mint:P40956|dip:DIP-2746N|ensemblfungi:YGL181W(gene)|ensemblfungi:YGL181W_mRNA(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0006897"(endocytosis)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010512"(negative regulation of phosphatidylinositol biosynthetic process)|go:"GO:0030479"(actin cortical patch)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR037278|interpro:IPR038508|sgd:YGL181W(identity)	go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|ensembl:ENSG00000143006(gene)|ensembl:ENST00000371445(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007281"(germ cell development)|go:"GO:0007548"(sex differentiation)|go:"GO:0046872"(metal ion binding)|interpro:IPR001275(DM DNA-binding)|interpro:IPR026607|interpro:IPR036407|mint:Q96MA1|refseq:NP_149056.1|ensembl:ENSP00000360500|entrezgene/locuslink:63948(identity)	-	crc64:D687E3BF6B620795	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:8kgpssCRrHiTHsFaOH2nDK6EIjk559292	rogid:GU1xgsv/Oyy91PEorOlxBqAvIzc9606	intact-crc:8BF53442401D725D|rigid:uwFrWjBNeLBqWbAyoWmobXU9zyQ	false	-	sufficient binding region:154-342	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40958	uniprotkb:Q5JR59-3	intact:EBI-10362|ensemblfungi:YJL030W|uniprotkb:D6VWF2	intact:EBI-11522433|ensembl:ENSP00000370186	psi-mi:mad2_yeast(display_long)|uniprotkb:MAD2(gene name)|psi-mi:MAD2(display_short)|uniprotkb:J1256(orf name)|uniprotkb:YJL030W(locus name)	psi-mi:q5jr59-3(display_long)|uniprotkb:MTUS2(gene name)|psi-mi:MTUS2(display_short)|uniprotkb:CAZIP(gene name synonym)|uniprotkb:Cardiac zipper protein(gene name synonym)|uniprotkb:KIAA0774(gene name synonym)|uniprotkb:Microtubule plus-end tracking protein TIP150(gene name synonym)|uniprotkb:TIP150(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11531720|imex:IM-24995-982	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003567|ensemblfungi:YJL030W(gene)|ensemblfungi:YJL030W_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0033597"(mitotic checkpoint complex)|go:"GO:0044774"(mitotic DNA integrity checkpoint signaling)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051301"(cell division)|go:"GO:0051312"(chromosome decondensation)|go:"GO:1902499"(positive regulation of protein autoubiquitination)|interpro:IPR003511(DNA-binding HORMA)|interpro:IPR027097|interpro:IPR036570|reactome:R-SCE-141405|reactome:R-SCE-141430|refseq:NP_012504.3|dip:DIP-815N|mint:P40958|sgd:YJL030W(identity)	ensembl:ENSG00000132938(gene)|ensembl:ENST00000380808(transcript)|intact:EBI-742948(isoform-parent)|uniprotkb:Q5JR59-3(isoform-parent)|entrezgene/locuslink:23281(identity)	-	-	isoform-comment:No experimental confirmation available.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:0pxFckODTcklkGn+JcczltjSHRU559292	rogid:npId9tC7VoLN/jteoBiRbSYChPs9606	intact-crc:AC2023CB6F66B1E0|rigid:GcG2aYAqQEdnpQZa1GwLlJzofBc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9NRA8-2	uniprotkb:P40956	intact:EBI-11531709|ensembl:ENSP00000342927	intact:EBI-7968|uniprotkb:D6VTX2|ensemblfungi:YGL181W	psi-mi:q9nra8-2(display_long)|uniprotkb:Eukaryotic translation initiation factor 4E nuclear import factor 1(gene name synonym)|uniprotkb:EIF4ENIF1(gene name)|psi-mi:EIF4ENIF1(display_short)	psi-mi:gts1_yeast(display_long)|uniprotkb:YGL181W(locus name)|uniprotkb:GTS1(gene name)|psi-mi:GTS1(display_short)|uniprotkb:LSR1(gene name synonym)|uniprotkb:Protein LSR1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11531707|imex:IM-24995-981	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000184708(gene)|ensembl:ENST00000344710(transcript)|intact:EBI-301024(isoform-parent)|uniprotkb:Q9NRA8-2(isoform-parent)|entrezgene/locuslink:56478(identity)	refseq:NP_011334.1|sgd:S000003149|mint:P40956|dip:DIP-2746N|ensemblfungi:YGL181W(gene)|ensemblfungi:YGL181W_mRNA(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0006897"(endocytosis)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010512"(negative regulation of phosphatidylinositol biosynthetic process)|go:"GO:0030479"(actin cortical patch)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR037278|interpro:IPR038508|sgd:YGL181W(identity)	-	isoform-comment:No experimental confirmation available.	crc64:D687E3BF6B620795	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:VQghhcptYh8k783QTJChpGbP/lU9606	rogid:8kgpssCRrHiTHsFaOH2nDK6EIjk559292	intact-crc:ECBC624A024020CE|rigid:WE2+SYyQQcCNUzCbGUz+wCkFZFo	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40956	uniprotkb:Q9NRA8	intact:EBI-7968|uniprotkb:D6VTX2|ensemblfungi:YGL181W	intact:EBI-301024|uniprotkb:B1AKL2|uniprotkb:Q8NCF2|uniprotkb:Q9H708|uniprotkb:B2RBF1|ensembl:ENSP00000328103|ensembl:ENSP00000380659|intact:EBI-877635|uniprotkb:B1AKL3	psi-mi:gts1_yeast(display_long)|uniprotkb:YGL181W(locus name)|uniprotkb:GTS1(gene name)|psi-mi:GTS1(display_short)|uniprotkb:LSR1(gene name synonym)|uniprotkb:Protein LSR1(gene name synonym)	psi-mi:4et_human(display_long)|uniprotkb:EIF4ENIF1(gene name)|psi-mi:EIF4ENIF1(display_short)|uniprotkb:Eukaryotic translation initiation factor 4E nuclear import factor 1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11531698|imex:IM-24995-980	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011334.1|sgd:S000003149|mint:P40956|dip:DIP-2746N|ensemblfungi:YGL181W(gene)|ensemblfungi:YGL181W_mRNA(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0006897"(endocytosis)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010512"(negative regulation of phosphatidylinositol biosynthetic process)|go:"GO:0030479"(actin cortical patch)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR037278|interpro:IPR038508|sgd:YGL181W(identity)	ensembl:ENSP00000328103|ensembl:ENST00000344710|ensembl:ENSP00000342927|ensembl:ENSP00000380659|ensembl:ENSG00000184708(gene)|ensembl:ENST00000330125(transcript)|ensembl:ENST00000397525(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0016020"(membrane)|go:"GO:0016605"(PML body)|go:"GO:0016607"(nuclear speck)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019900"(kinase binding)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0033962"(P-body assembly)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0106289"(negative regulation of deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:1905618"(positive regulation of miRNA-mediated gene silencing by inhibition of translation)|interpro:IPR018862|mint:Q9NRA8|rcsb pdb:5ANR|rcsb pdb:6F9W|rcsb pdb:6X2R|refseq:NP_001157973.1|refseq:NP_001157974.1|refseq:NP_062817.2|refseq:XP_011528582.1|refseq:XP_011528583.1|refseq:XP_005261743.1|refseq:XP_005261744.1|refseq:XP_005261745.1|refseq:XP_016884353.1|entrezgene/locuslink:56478(identity)	-	crc64:D687E3BF6B620795	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:8kgpssCRrHiTHsFaOH2nDK6EIjk559292	rogid:4A9mF81S/ePAraruTNYgovUdkT49606	intact-crc:91442B4E43F5F032|rigid:M4JgLF5EA5zU5iL3Fn5trsEiHac	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q13137	uniprotkb:P41911	intact:EBI-739580|uniprotkb:B4DDC4|uniprotkb:E7ENK0|uniprotkb:Q53FQ5|uniprotkb:Q53HB5|uniprotkb:Q6IBN9|uniprotkb:Q9BTF7|uniprotkb:B2RBT0|ensembl:ENSP00000258947|uniprotkb:B4E0C0|uniprotkb:E7ETP5|uniprotkb:B4DDT4|uniprotkb:B4DP36|uniprotkb:E9PBE5	intact:EBI-7791|uniprotkb:P50905|uniprotkb:D6W208|ensemblfungi:YOL059W	psi-mi:caco2_human(display_long)|uniprotkb:CALCOCO2(gene name)|psi-mi:CALCOCO2(display_short)|uniprotkb:NDP52(gene name synonym)|uniprotkb:Nuclear domain 10 protein NDP52(gene name synonym)|uniprotkb:Antigen nuclear dot 52 kDa protein(gene name synonym)|uniprotkb:Nuclear dot protein 52(gene name synonym)	psi-mi:gpd2_yeast(display_long)|uniprotkb:GPD2(gene name)|psi-mi:GPD2(display_short)|uniprotkb:GPD3(gene name synonym)|uniprotkb:YOL059W(locus name)|uniprotkb:O1222(orf name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11531747|imex:IM-24995-985	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001248319.1|refseq:NP_001248320.1|refseq:NP_001248322.1|refseq:NP_005822.1|ensembl:ENSG00000136436(gene)|ensembl:ENST00000258947(transcript)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016032"(viral process)|go:"GO:0016605"(PML body)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0098792"(xenophagy)|go:"GO:1901098"(positive regulation of autophagosome maturation)|interpro:IPR041611|interpro:IPR041641|mint:Q13137|rcsb pdb:2MXP|rcsb pdb:3VVV|rcsb pdb:3VVW|rcsb pdb:4GXL|rcsb pdb:4HAN|rcsb pdb:4XKL|rcsb pdb:5AAQ|rcsb pdb:5Z7A|rcsb pdb:5Z7L|refseq:NP_001248324.1|dip:DIP-57534N|entrezgene/locuslink:10241(identity)	refseq:NP_014582.1|sgd:S000005420|dip:DIP-1348N|mint:P41911|ensemblfungi:YOL059W(gene)|ensemblfungi:YOL059W_mRNA(transcript)|go:"GO:0004367"(glycerol-3-phosphate dehydrogenase [NAD+] activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006071"(glycerol metabolic process)|go:"GO:0006072"(glycerol-3-phosphate metabolic process)|go:"GO:0006116"(NADH oxidation)|go:"GO:0009331"(glycerol-3-phosphate dehydrogenase complex)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046168"(glycerol-3-phosphate catabolic process)|go:"GO:0051287"(NAD binding)|interpro:IPR006109(NAD-dependent glycerol-3-phosphate dehydrogenase, C-terminal)|interpro:IPR006168(NAD-dependent glycerol-3-phosphate dehydrogenase)|interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|interpro:IPR011128(NAD-dependent glycerol-3-phosphate dehydrogenase, N-terminal)|interpro:IPR013328(Dehydrogenase, multihelical)|interpro:IPR017751(NAD-dependent glycerol-3-phosphate dehydrogenase, eukaryotic)|interpro:IPR036291|reactome:R-SCE-1483166|sgd:YOL059W(identity)	-	crc64:609B121DA1A9DCB8	crc64:FA6C07034D3EC720	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:N/GPJUGBK+Dh5Cg+csmafphuo9M9606	rogid:RX8TddHnpQdQdh6KN8y9IR8Jgrg559292	intact-crc:DF66B1104B29E10B|rigid:3CRaXf3nmzXRGwe6e1gllePohpw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12800	uniprotkb:P41902	intact:EBI-717422|uniprotkb:Q12801|uniprotkb:Q9UD77|uniprotkb:A8K5E9|uniprotkb:Q9UD75|ensembl:ENSP00000257915	intact:EBI-5162|uniprotkb:D6W296	psi-mi:tfcp2_human(display_long)|uniprotkb:Transcription factor LSF(gene name synonym)|uniprotkb:SAA3 enhancer factor(gene name synonym)|uniprotkb:TFCP2(gene name)|psi-mi:TFCP2(display_short)|uniprotkb:LSF(gene name synonym)|uniprotkb:SEF(gene name synonym)	psi-mi:crs5_yeast(display_long)|uniprotkb:CRS5(gene name)|psi-mi:CRS5(display_short)|uniprotkb:O2675(orf name)|uniprotkb:YOR031W(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11531738|imex:IM-24995-984	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001166923.1|refseq:NP_001166924.1|refseq:NP_005644.2|ensembl:ENSG00000135457(gene)|ensembl:ENST00000257915(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR007604(CP2 transcription factor)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR037599|interpro:IPR041418|mint:Q12800|entrezgene/locuslink:7024(identity)	sgd:S000005557|dip:DIP-5511N|go:"GO:0005507"(copper ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0010038"(response to metal ion)|interpro:IPR035715|sgd:YOR031W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:M7mQ08NDYxuawmUEKRgjSdIr+Og9606	rogid:j4oJEwGSOVJeLFRydjF0k9ASq14559292	intact-crc:66CA69B5E18C552F|rigid:Ptae9zJfdvTrIUq6XDJvdTnn7GM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40959	uniprotkb:O43791	intact:EBI-11636|ensemblfungi:YMR004W|uniprotkb:D6VZH9	intact:EBI-743549|uniprotkb:Q53HJ1|uniprotkb:B2R6S3|uniprotkb:D3DTW7|ensembl:ENSP00000240327|ensembl:ENSP00000377001|ensembl:ENSP00000420908|ensembl:ENSP00000424119|ensembl:ENSP00000425905|ensembl:ENSP00000426986|ensembl:ENSP00000499562	psi-mi:mvp1_yeast(display_long)|uniprotkb:MVP1(gene name)|psi-mi:MVP1(display_short)|uniprotkb:YM8270.06(orf name)|uniprotkb:YMR004W(locus name)	psi-mi:spop_human(display_long)|uniprotkb:HIB homolog 1(gene name synonym)|uniprotkb:Roadkill homolog 1(gene name synonym)|uniprotkb:SPOP(gene name)|psi-mi:SPOP(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11531729|imex:IM-24995-983	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YMR004W(gene)|ensemblfungi:YMR004W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0016020"(membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0097320"(plasma membrane tubulation)|interpro:IPR001683(Phox-like)|interpro:IPR028662|interpro:IPR035704|interpro:IPR036871|rcsb pdb:6Q0X|refseq:NP_013717.1|sgd:S000004606|mint:P40959|dip:DIP-1764N|sgd:YMR004W(identity)	refseq:NP_001007227.1|refseq:NP_001007228.1|refseq:NP_001007229.1|refseq:NP_001007230.1|refseq:NP_001007231.1|refseq:NP_003554.1|refseq:XP_005257780.1|refseq:XP_005257781.1|ensembl:ENSG00000121067(gene)|ensembl:ENST00000347630(transcript)|ensembl:ENST00000393328(transcript)|ensembl:ENST00000503676(transcript)|ensembl:ENST00000504102(transcript)|ensembl:ENST00000509079(transcript)|ensembl:ENST00000514121(transcript)|ensembl:ENST00000665825(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0016607"(nuclear speck)|go:"GO:0030162"(regulation of proteolysis)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR034089|mint:O43791|rcsb pdb:2CR2|rcsb pdb:3HQH|rcsb pdb:3HQI|rcsb pdb:3HQL|rcsb pdb:3HQM|rcsb pdb:3HSV|rcsb pdb:3HTM|rcsb pdb:3HU6|rcsb pdb:3IVB|rcsb pdb:3IVQ|rcsb pdb:3IVV|rcsb pdb:4EOZ|rcsb pdb:4HS2|rcsb pdb:4J8Z|rcsb pdb:4O1V|rcsb pdb:6F8F|rcsb pdb:6F8G|rcsb pdb:6I41|rcsb pdb:6I5P|rcsb pdb:6I68|rcsb pdb:6I7A|rcsb pdb:7D3D|rcsb pdb:7LIN|rcsb pdb:7LIO|rcsb pdb:7LIP|rcsb pdb:7LIQ|reactome:R-HSA-5632684|go:"GO:0005634"(nucleus)|refseq:XP_016880693.1|dip:DIP-50517N|entrezgene/locuslink:8405(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:3IrMPCYXP5yb2l52Uhu2DiEuNdI559292	rogid:PC9ofpvk14xwTnnqT590/YRnx/49606	intact-crc:ED25B61CC869C74A|rigid:W0IEqqkqzN/r9Rp/S5G9rR8DnFc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40692	uniprotkb:P42843	intact:EBI-744248|uniprotkb:B4DI13|uniprotkb:B4DQ11|uniprotkb:E9PCU2|ensembl:ENSP00000231790	intact:EBI-28370|uniprotkb:Q6B2L9|uniprotkb:D6W0N4|ensemblfungi:YNL311C	psi-mi:mlh1_human(display_long)|uniprotkb:MutL protein homolog 1(gene name synonym)|uniprotkb:MLH1(gene name)|psi-mi:MLH1(display_short)|uniprotkb:COCA2(gene name synonym)	psi-mi:skp2_yeast(display_long)|uniprotkb:N0376(orf name)|uniprotkb:YNL311C(locus name)|uniprotkb:SKP2(gene name)|psi-mi:SKP2(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11531775|imex:IM-24995-988	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000240.1|refseq:NP_001161089.1|refseq:NP_001161090.1|refseq:NP_001161091.1|refseq:NP_001245200.1|refseq:NP_001245202.1|refseq:NP_001245203.1|dip:DIP-27601N|refseq:XP_005265220.1|refseq:XP_005265221.1|ensembl:ENSG00000076242(gene)|ensembl:ENST00000231790(transcript)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005712"(chiasma)|go:"GO:0005715"(late recombination nodule)|go:"GO:0006298"(mismatch repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0007060"(male meiosis chromosome segregation)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0009617"(response to bacterium)|go:"GO:0016020"(membrane)|go:"GO:0016321"(female meiosis chromosome segregation)|go:"GO:0016446"(somatic hypermutation of immunoglobulin genes)|go:"GO:0019899"(enzyme binding)|go:"GO:0032137"(guanine/thymine mispair binding)|go:"GO:0032300"(mismatch repair complex)|go:"GO:0032389"(MutLalpha complex)|go:"GO:0043060"(meiotic metaphase I plate congression)|go:"GO:0045141"(meiotic telomere clustering)|go:"GO:0045190"(isotype switching)|go:"GO:0045950"(negative regulation of mitotic recombination)|go:"GO:0048298"(positive regulation of isotype switching to IgA isotypes)|go:"GO:0048304"(positive regulation of isotype switching to IgG isotypes)|go:"GO:0048477"(oogenesis)|go:"GO:0051257"(meiotic spindle midzone assembly)|interpro:IPR002099(DNA mismatch repair protein)|interpro:IPR013507(DNA mismatch repair protein, C-terminal)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR014762(DNA mismatch repair, conserved site)|interpro:IPR020568|interpro:IPR032189|interpro:IPR036890|interpro:IPR038973|mint:P40692|rcsb pdb:3RBN|rcsb pdb:4P7A|rcsb pdb:5U5P|reactome:R-HSA-5358565|reactome:R-HSA-5358606|reactome:R-HSA-5545483|reactome:R-HSA-5632987|reactome:R-HSA-6796648|reactome:R-HSA-912446|entrezgene/locuslink:4292(identity)	refseq:NP_014088.1|sgd:S000005255|dip:DIP-1971N|ensemblfungi:YNL311C(gene)|ensemblfungi:YNL311C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031335"(regulation of sulfur amino acid metabolic process)|go:"GO:0044257"(cellular protein catabolic process)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR036047|sgd:YNL311C(identity)	-	-	crc64:81102168449051BC	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:v/ydpM1Cf5bF27dC+3JF6XXMp0Q9606	rogid:cvjKu9olqbvbZPvhBL6DK754CVA559292	intact-crc:D5E7718E608023D9|rigid:kYwRq4BtBtFhSAL5N1qqzkJjwfs	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96BA8	uniprotkb:P42836	intact:EBI-6942903|ensembl:ENSP00000481956|intact:MINT-268046|intact:MINT-8162577|uniprotkb:Q8N2D5|uniprotkb:Q96CP0	intact:EBI-28414|uniprotkb:D6W0M1|ensemblfungi:YNL326C	psi-mi:cr3l1_human(display_long)|uniprotkb:CREB3L1(gene name)|psi-mi:CREB3L1(display_short)|uniprotkb:OASIS(gene name synonym)|uniprotkb:PSEC0238(orf name)|uniprotkb:Old astrocyte specifically-induced substance(gene name synonym)	psi-mi:pfa3_yeast(display_long)|uniprotkb:YNL326C(locus name)|uniprotkb:N0325(orf name)|uniprotkb:PFA3(gene name)|psi-mi:PFA3(display_short)|uniprotkb:Protein fatty acyltransferase 3(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11531765|imex:IM-24995-987	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157613(gene)|ensembl:ENST00000621158(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0070278"(extracellular matrix constituent secretion)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029805|mint:Q96BA8|reactome:R-HSA-8874211|refseq:NP_443086.1|entrezgene/locuslink:90993(identity)	refseq:NP_014073.1|sgd:S000005270|dip:DIP-4833N|ensemblfungi:YNL326C(gene)|ensemblfungi:YNL326C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0042144"(vacuole fusion, non-autophagic)|interpro:IPR001594(Zinc finger, DHHC-type)|sgd:YNL326C(identity)	-	comment:mint|function:"Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE"	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:sMWUFmBeBBCO+T0Y2CuB/un1lBg9606	rogid:wDUIzJoLnfaV6fo96hca+beyKb4559292	intact-crc:1261C3DA48E26396|rigid:+paqGEhcUkhG4sNChbNbQOAbHo0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8NHQ1	uniprotkb:P41911	intact:EBI-739624|ensembl:ENSP00000264982|ensembl:ENSP00000419231|uniprotkb:Q96B31|uniprotkb:Q9H2C3|uniprotkb:Q9H2Z1|uniprotkb:Q9H940|uniprotkb:D3DNE9|uniprotkb:B7Z5I8|uniprotkb:B7Z7E8|uniprotkb:F5GZX8	intact:EBI-7791|uniprotkb:P50905|uniprotkb:D6W208|ensemblfungi:YOL059W	psi-mi:cep70_human(display_long)|uniprotkb:CEP70(gene name)|psi-mi:CEP70(display_short)|uniprotkb:BITE(gene name synonym)|uniprotkb:p10-binding protein(gene name synonym)	psi-mi:gpd2_yeast(display_long)|uniprotkb:GPD2(gene name)|psi-mi:GPD2(display_short)|uniprotkb:GPD3(gene name synonym)|uniprotkb:YOL059W(locus name)|uniprotkb:O1222(orf name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11531756|imex:IM-24995-986	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114107(gene)|ensembl:ENST00000264982(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|interpro:IPR019734|interpro:IPR037692|mint:Q8NHQ1|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|ensembl:ENST00000484888(transcript)|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_077817.2|refseq:XP_016862764.1|refseq:NP_001275893.1|refseq:NP_001275894.1|refseq:NP_001275895.1|refseq:NP_001275896.1|refseq:NP_001307527.1|refseq:NP_001307529.1|entrezgene/locuslink:80321(identity)	refseq:NP_014582.1|sgd:S000005420|dip:DIP-1348N|mint:P41911|ensemblfungi:YOL059W(gene)|ensemblfungi:YOL059W_mRNA(transcript)|go:"GO:0004367"(glycerol-3-phosphate dehydrogenase [NAD+] activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006071"(glycerol metabolic process)|go:"GO:0006072"(glycerol-3-phosphate metabolic process)|go:"GO:0006116"(NADH oxidation)|go:"GO:0009331"(glycerol-3-phosphate dehydrogenase complex)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046168"(glycerol-3-phosphate catabolic process)|go:"GO:0051287"(NAD binding)|interpro:IPR006109(NAD-dependent glycerol-3-phosphate dehydrogenase, C-terminal)|interpro:IPR006168(NAD-dependent glycerol-3-phosphate dehydrogenase)|interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|interpro:IPR011128(NAD-dependent glycerol-3-phosphate dehydrogenase, N-terminal)|interpro:IPR013328(Dehydrogenase, multihelical)|interpro:IPR017751(NAD-dependent glycerol-3-phosphate dehydrogenase, eukaryotic)|interpro:IPR036291|reactome:R-SCE-1483166|sgd:YOL059W(identity)	-	-	crc64:FA6C07034D3EC720	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:S4yveQWcvdVtAUX65gqrJ5Dv0Mc9606	rogid:RX8TddHnpQdQdh6KN8y9IR8Jgrg559292	intact-crc:39BDF5E1DD492DD5|rigid:Iu233k8WKSMtbV2xCJgemKCwEHI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P42937	uniprotkb:Q9UFD9	intact:EBI-23470|uniprotkb:D6VUY5|ensemblfungi:YGR203W	intact:EBI-10182375|uniprotkb:Q9UFQ5|uniprotkb:Q8IYP7|uniprotkb:Q9BY94|intact:EBI-28984856|ensembl:ENSP00000483386	psi-mi:ych1_yeast(display_long)|uniprotkb:YGR203W(locus name)|uniprotkb:G7731(orf name)|uniprotkb:YCH1(gene name)|psi-mi:YCH1(display_short)|uniprotkb:CDC25 homolog 1(gene name synonym)	psi-mi:rim3a_human(display_long)|uniprotkb:RIMBP3(gene name)|psi-mi:RIMBP3(display_short)|uniprotkb:KIAA1666(gene name synonym)|uniprotkb:RIMBP3A(gene name synonym)|uniprotkb:RIMS-binding protein 3.1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11531802|imex:IM-24995-991	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011719.1|sgd:S000003435|dip:DIP-885N|ensemblfungi:YGR203W(gene)|ensemblfungi:YGR203W_mRNA(transcript)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0004792"(thiosulfate sulfurtransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016311"(dephosphorylation)|go:"GO:0016791"(phosphatase activity)|interpro:IPR001763(Rhodanese-like)|interpro:IPR036873|rcsb pdb:3F4A|rcsb pdb:3FS5|sgd:YGR203W(identity)	refseq:NP_056487.1|ensembl:ENSP00000483386|ensembl:ENSG00000275793(gene)|ensembl:ENST00000619918(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007286"(spermatid development)|go:"GO:0009566"(fertilization)|go:"GO:0030156"(benzodiazepine receptor binding)|go:"GO:0045202"(synapse)|interpro:IPR001452(Src homology-3)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR035515|interpro:IPR036028|interpro:IPR036116|interpro:IPR040325|rcsb pdb:2EGE|entrezgene/locuslink:85376(identity)	-	crc64:41527DB282CBFF11	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:p8SYf/V7HMF1NdntyAYkfOBvlPk559292	rogid:iw34Gee4nqAH3pqUfCgQ6Jj++AA9606	intact-crc:1DD7481F582A4460|rigid:9l31IlXMhzvSc+WdrwcdhX/6RaY	false	-	sufficient binding region:838-1639	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P42937	uniprotkb:Q8N5R6	intact:EBI-23470|uniprotkb:D6VUY5|ensemblfungi:YGR203W	intact:EBI-740841|intact:EBI-953781|uniprotkb:B3KQ49|uniprotkb:A8K3U4|uniprotkb:A8MPQ6|uniprotkb:A8MV61|uniprotkb:A8MVU9|uniprotkb:Q9H5Q6|uniprotkb:Q8TAX6|intact:EBI-2320546|intact:EBI-11522976	psi-mi:ych1_yeast(display_long)|uniprotkb:YGR203W(locus name)|uniprotkb:G7731(orf name)|uniprotkb:YCH1(gene name)|psi-mi:YCH1(display_short)|uniprotkb:CDC25 homolog 1(gene name synonym)	psi-mi:ccd33_human(display_long)|uniprotkb:CCDC33(gene name)|psi-mi:CCDC33(display_short)|uniprotkb:Cancer/testis antigen 61(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11531793|imex:IM-24995-990	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011719.1|sgd:S000003435|dip:DIP-885N|ensemblfungi:YGR203W(gene)|ensemblfungi:YGR203W_mRNA(transcript)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0004792"(thiosulfate sulfurtransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016311"(dephosphorylation)|go:"GO:0016791"(phosphatase activity)|interpro:IPR001763(Rhodanese-like)|interpro:IPR036873|rcsb pdb:3F4A|rcsb pdb:3FS5|sgd:YGR203W(identity)	refseq:NP_079331.3|interpro:IPR000008(C2 calcium-dependent membrane targeting)|go:"GO:0005777"(peroxisome)|refseq:NP_001274110.1|refseq:NP_877592.2|mint:Q8N5R6|interpro:IPR035892|interpro:IPR039889|entrezgene/locuslink:80125(identity)	-	crc64:41527DB282CBFF11	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2021/11/30	rogid:p8SYf/V7HMF1NdntyAYkfOBvlPk559292	rogid:eEIn7pQyfdHWx8TeLJpYy0i/gww9606	intact-crc:051C8E8E68A45022|rigid:+vXoUJGEq5t7Gf9Xfd8nxl0T6uM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P42846	uniprotkb:Q9H190	intact:EBI-28360|uniprotkb:D6W0N7|ensemblfungi:YNL308C	intact:EBI-742426|ensembl:ENSP00000371233|uniprotkb:O95892|uniprotkb:Q5W0X1|uniprotkb:Q9BZ42|uniprotkb:Q9H567|uniprotkb:Q9NRY8|intact:EBI-28983470|ensembl:ENSP00000342935|ensembl:ENSP00000354013	psi-mi:kri1_yeast(display_long)|uniprotkb:YNL308C(locus name)|uniprotkb:N0388(orf name)|uniprotkb:KRR1-interacting protein 1(gene name synonym)|uniprotkb:KRI1(gene name)|psi-mi:KRI1(display_short)	psi-mi:sdcb2_human(display_long)|uniprotkb:Similar to TACIP18(gene name synonym)|uniprotkb:SDCBP2(gene name)|psi-mi:SDCBP2(display_short)|uniprotkb:SITAC18(gene name synonym)|uniprotkb:Syndecan-binding protein 2(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11531784|imex:IM-24995-989	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014091.1|sgd:S000005252|dip:DIP-4073N|mint:P42846|ensemblfungi:YNL308C(gene)|ensemblfungi:YNL308C_mRNA(transcript)|go:"GO:0000447"("endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0005730"(nucleolus)|go:"GO:0030686"(90S preribosome)|interpro:IPR018034|interpro:IPR024626|sgd:YNL308C(identity)	refseq:NP_001186713.1|refseq:NP_056500.2|refseq:NP_536737.3|ensembl:ENSP00000342935|ensembl:ENSP00000354013|ensembl:ENST00000381808|ensembl:ENSP00000371229|ensembl:ENSP00000371233|ensembl:ENSG00000125775(gene)|ensembl:ENST00000360779(transcript)|ensembl:ENST00000381812(transcript)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007399"(nervous system development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016607"(nuclear speck)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046907"(intracellular transport)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036034|interpro:IPR041489|ensembl:ENST00000339987(transcript)|entrezgene/locuslink:27111(identity)	-	crc64:3B637571EDB05EA6	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:NhrYBQD07sx7vTVgiDFulg1FrAI559292	rogid:vlEtVZkwLTte5PJ4i8ce+SwE/4Y9606	intact-crc:9C1ECFE9CC43E4ED|rigid:7fCfnus8xIBHPRTPaAKnPuow3RE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q99750	uniprotkb:P42947	intact:EBI-724076|ensembl:ENSP00000230321|ensembl:ENSP00000362142	intact:EBI-26023|uniprotkb:D6VW77|ensemblfungi:YJL107C	psi-mi:mdfi_human(display_long)|uniprotkb:Myogenic repressor I-mf(gene name synonym)|uniprotkb:MDFI(gene name)|psi-mi:MDFI(display_short)	psi-mi:yjk7_yeast(display_long)|uniprotkb:J0813(orf name)|uniprotkb:YJL107C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11531824|imex:IM-24995-993	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005577.1|ensembl:ENSG00000112559(gene)|ensembl:ENST00000230321(transcript)|ensembl:ENST00000373051(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR026134|mint:Q99750|refseq:NP_001287733.1|refseq:NP_001287734.1|refseq:NP_001287735.1|entrezgene/locuslink:4188(identity)	sgd:S000003643|refseq:NP_012428.1|mint:P42947|dip:DIP-5095N|ensemblfungi:YJL107C(gene)|ensemblfungi:YJL107C_mRNA(transcript)|interpro:IPR010619(Protein of unknown function DUF1212)|sgd:YJL107C(identity)	-	-	crc64:D7659D1955F5677F	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:V3vU0fihMOW18DMHAiDbuZ3asNU9606	rogid:U2SdxE3xuNnsKGX/4Gb0dpB6M+w559292	intact-crc:90C4F643471CCEBF|rigid:SfauxaIjEe1YZMuZdEusbsmH1v8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P42944	uniprotkb:Q08379	intact:EBI-8042|uniprotkb:D6VW74|ensemblfungi:YJL110C	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	psi-mi:gzf3_yeast(display_long)|uniprotkb:GZF3(gene name)|psi-mi:GZF3(display_short)|uniprotkb:J0806(orf name)|uniprotkb:YJL110C(locus name)	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11531813|imex:IM-24995-992	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012425.1|sgd:S000003646|mint:P42944|dip:DIP-1359N|ensemblfungi:YJL110C(gene)|ensemblfungi:YJL110C_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0090295"(nitrogen catabolite repression of transcription)|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR039355|reactome:R-SCE-9018519|sgd:YJL110C(identity)	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N|entrezgene/locuslink:2801(identity)	-	crc64:807243799BFAB704	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2017/05/26	rogid:HOMBFcxVuABRuzPHcnDG87+R6sQ559292	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	intact-crc:C740A64AEC4F63EA|rigid:6LN/DmegS/tGLsg5/MUSFS6ztsk	false	-	sufficient binding region:383-1002	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P43556	uniprotkb:Q9UJ70-2	intact:EBI-22845|uniprotkb:D6VTI3|ensemblfungi:YFL047W	intact:EBI-11526455|ensembl:ENSP00000389087|ensembl:ENSP00000477639	psi-mi:rgd2_yeast(display_long)|uniprotkb:RGD2(gene name)|psi-mi:RGD2(display_short)|uniprotkb:YFL047W(locus name)	psi-mi:q9uj70-2(display_long)|uniprotkb:GlcNAc kinase(gene name synonym)|uniprotkb:NAGK(gene name)|psi-mi:NAGK(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11531851|imex:IM-24995-996	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_428268.1|sgd:S000001847|dip:DIP-4958N|mint:P43556|go:"GO:0005935"(cellular bud neck)|interpro:IPR031160|reactome:R-SCE-8856828|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0032153"(cell division site)|interpro:IPR000198(RhoGAP)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR027267|ensemblfungi:YFL047W(gene)|ensemblfungi:YFL047W_mRNA(transcript)|go:"GO:0000935"(division septum)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005934"(cellular bud tip)|sgd:YFL047W(identity)	intact:EBI-372578(isoform-parent)|ensembl:ENSG00000124357(gene)|ensembl:ENST00000455662(transcript)|ensembl:ENST00000613852(transcript)|uniprotkb:Q9UJ70-2(isoform-parent)|entrezgene/locuslink:55577(identity)	-	crc64:52CF174C5F650157	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:TaphLAmYObi9RXMbE2tJDrHtVxA559292	rogid:zoy4C+HK341UnmDRUlMuJucczr89606	intact-crc:EC83C1BE013A67C1|rigid:7yBeKNZ0uHkUv4s/ch83jqe0tK4	false	-	sufficient binding region:47-390	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P43556	uniprotkb:Q8WW24	intact:EBI-22845|uniprotkb:D6VTI3|ensemblfungi:YFL047W	intact:EBI-750487|ensembl:ENSP00000295201	psi-mi:rgd2_yeast(display_long)|uniprotkb:RGD2(gene name)|psi-mi:RGD2(display_short)|uniprotkb:YFL047W(locus name)	psi-mi:tekt4_human(display_long)|uniprotkb:TEKT4(gene name)|psi-mi:TEKT4(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11531842|imex:IM-24995-995	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_428268.1|sgd:S000001847|dip:DIP-4958N|mint:P43556|go:"GO:0005935"(cellular bud neck)|interpro:IPR031160|reactome:R-SCE-8856828|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0032153"(cell division site)|interpro:IPR000198(RhoGAP)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR027267|ensemblfungi:YFL047W(gene)|ensemblfungi:YFL047W_mRNA(transcript)|go:"GO:0000935"(division septum)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005934"(cellular bud tip)|sgd:YFL047W(identity)	refseq:NP_653306.1|ensembl:ENSG00000163060(gene)|ensembl:ENST00000295201(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0036126"(sperm flagellum)|go:"GO:0060271"(cilium assembly)|go:"GO:0060294"(cilium movement involved in cell motility)|interpro:IPR000435(Tektin)|entrezgene/locuslink:150483(identity)	-	crc64:52CF174C5F650157	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:TaphLAmYObi9RXMbE2tJDrHtVxA559292	rogid:uSPBMKPN9VTr6rsdxgUPpfWynIA9606	intact-crc:4D4B8FA0465F34C9|rigid:W5rR4lur6RJr3g69DaeB1n63rxQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P43552	uniprotkb:P46379-2	intact:EBI-22855|uniprotkb:D6VTH9|ensemblfungi:YFL051C	intact:EBI-10988864|ensembl:ENSP00000211379|ensembl:ENSP00000365143|ensembl:ENSP00000372938|ensembl:ENSP00000372940|ensembl:ENSP00000389121|ensembl:ENSP00000410156|ensembl:ENSP00000412110|ensembl:ENSP00000413698	psi-mi:yff1_yeast(display_long)|uniprotkb:YFL051C(locus name)	psi-mi:p46379-2(display_long)|uniprotkb:BAG6(gene name)|psi-mi:BAG6(display_short)|uniprotkb:BAG family molecular chaperone regulator 6(gene name synonym)|uniprotkb:BAT3(gene name synonym)|uniprotkb:BCL2-associated athanogene 6(gene name synonym)|uniprotkb:G3(gene name synonym)|uniprotkb:HLA-B-associated transcript 3(gene name synonym)|uniprotkb:Protein G3(gene name synonym)|uniprotkb:Protein Scythe(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11531833|imex:IM-24995-994	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_116576.1|sgd:S000001843|dip:DIP-4270N|ensemblfungi:YFL051C(gene)|ensemblfungi:YFL051C_mRNA(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|sgd:YFL051C(identity)	intact:EBI-347552(isoform-parent)|uniprotkb:P46379-2(isoform-parent)|ensembl:ENSG00000096155(gene)|ensembl:ENSG00000204463(gene)|ensembl:ENSG00000229524(gene)|ensembl:ENSG00000233348(gene)|ensembl:ENST00000211379(transcript)|ensembl:ENST00000375976(transcript)|ensembl:ENST00000383446(transcript)|ensembl:ENST00000383448(transcript)|ensembl:ENST00000417144(transcript)|ensembl:ENST00000419847(transcript)|ensembl:ENST00000442479(transcript)|ensembl:ENST00000443182(transcript)|entrezgene/locuslink:7917(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:oiB9m73Dyv5h04x667Dlwx3MiC8559292	rogid:7y9hxqfcTmnCBRON6qNoHPCdODY9606	intact-crc:CFD7608ABFF2C6D1|rigid:1YisNh/uvaM61W64I65X41K4b1E	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P43592	uniprotkb:O95751	intact:EBI-22932|uniprotkb:D6VTN8|ensemblfungi:YFR008W	intact:EBI-740738|ensembl:ENSP00000359557|uniprotkb:Q6IAR6	psi-mi:far7_yeast(display_long)|uniprotkb:YFR008W(locus name)|uniprotkb:FAR7(gene name)|psi-mi:FAR7(display_short)	psi-mi:ldoc1_human(display_long)|uniprotkb:Leucine zipper protein down-regulated in cancer cells(gene name synonym)|uniprotkb:LDOC1(gene name)|psi-mi:LDOC1(display_short)|uniprotkb:BCUR1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11531881|imex:IM-24995-999	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000001904|refseq:NP_116663.1|dip:DIP-1315N|mint:P43592|ensemblfungi:YFR008W(gene)|ensemblfungi:YFR008W_mRNA(transcript)|go:"GO:0000321"(re-entry into mitotic cell cycle after pheromone arrest)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|sgd:YFR008W(identity)	refseq:NP_036449.1|ensembl:ENSG00000182195(gene)|ensembl:ENST00000370526(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071225"(cellular response to muramyl dipeptide)|interpro:IPR032549|interpro:IPR032567|entrezgene/locuslink:23641(identity)	-	crc64:81156978FF7AAD54	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:RB7IaPAzOtEtryalHHz8psxOYqw559292	rogid:Ediu0oNiZ/+YVY8l3fNdgP5A+v09606	intact-crc:EC01E16F20FBC040|rigid:O7PdVOCZde1KYP3b4BIZbVVrlrE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P43588	uniprotkb:Q9GZT8	intact:EBI-11219|uniprotkb:Q8J0T5|uniprotkb:D6VTN4|ensemblfungi:YFR004W	intact:EBI-740897|uniprotkb:Q9H2D2|uniprotkb:Q9HC18|uniprotkb:Q6X735|uniprotkb:Q53TX4|ensembl:ENSP00000386394|ensembl:ENSP00000387315|ensembl:ENSP00000498853	psi-mi:rpn11_yeast(display_long)|uniprotkb:YFR004W(locus name)|uniprotkb:RPN11(gene name)|psi-mi:RPN11(display_short)|uniprotkb:MPR1(gene name synonym)|uniprotkb:Protein MPR1(gene name synonym)|uniprotkb:26S proteasome regulatory subunit RPN11(gene name synonym)	psi-mi:nif3l_human(display_long)|uniprotkb:Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 1 protein(gene name synonym)|uniprotkb:MDS015(orf name)|uniprotkb:My018(orf name)|uniprotkb:NIF3L1(gene name)|psi-mi:NIF3L1(display_short)|uniprotkb:ALS2CR1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11531872|imex:IM-24995-998	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YFR004W(gene)|ensemblfungi:YFR004W_mRNA(transcript)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0016559"(peroxisome fission)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043248"(proteasome assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0061578"(Lys63-specific deubiquitinase activity)|go:"GO:0070628"(proteasome binding)|go:"GO:1902906"(proteasome storage granule assembly)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR024969|interpro:IPR035299|interpro:IPR037518|rcsb pdb:3J47|rcsb pdb:3JCK|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:4O8X|rcsb pdb:4O8Y|rcsb pdb:4OCL|rcsb pdb:4OCM|go:"GO:0070122"(isopeptidase activity)|rcsb pdb:4OCN|rcsb pdb:4OWP|rcsb pdb:5A5B|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5MPD|rcsb pdb:5MPE|rcsb pdb:5U4P|rcsb pdb:5W83|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-5689901|reactome:R-SCE-6798695|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|refseq:NP_116659.1|sgd:S000001900|mint:P43588|dip:DIP-1573N|sgd:YFR004W(identity)	refseq:NP_001129511.1|refseq:NP_001135827.1|refseq:NP_068596.2|refseq:XP_011509887.1|refseq:XP_011509884.1|refseq:XP_011509885.1|refseq:XP_011509886.1|refseq:NP_001135828.1|refseq:XP_005246799.1|refseq:XP_016860119.1|ensembl:ENSG00000196290(gene)|ensembl:ENST00000409020(transcript)|ensembl:ENST00000409357(transcript)|ensembl:ENST00000651500(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:1903507"(negative regulation of nucleic acid-templated transcription)|interpro:IPR002678(NGG1p interacting factor 3, NIF3)|interpro:IPR017222(Uncharacterised conserved protein UCP037490, NIF3, eukaryota)|interpro:IPR036069|mint:Q9GZT8|entrezgene/locuslink:60491(identity)	-	crc64:9DDE8BD74890894D	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:f3lAMY9siMcO2dAOfKvVrvKzfNM559292	rogid:Vvyb7CJpcwGtGAVKT2Zoqycr2yQ9606	intact-crc:CBD04BEC0C66D9AE|rigid:8KKyIvG5++kvD+nzm1lq/NQVyMQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O43639	uniprotkb:P43569	intact:EBI-713635|uniprotkb:Q9BWN9|uniprotkb:Q9UIC3|ensembl:ENSP00000233154|ensembl:ENSP00000377018|uniprotkb:D3DVK1	intact:EBI-22808|uniprotkb:D6VTK2|ensemblfungi:YFL028C	psi-mi:nck2_human(display_long)|uniprotkb:NCK adaptor protein 2(gene name synonym)|uniprotkb:SH2/SH3 adaptor protein NCK-beta(gene name synonym)|uniprotkb:NCK2(gene name)|psi-mi:NCK2(display_short)|uniprotkb:GRB4(gene name synonym)|uniprotkb:Growth factor receptor-bound protein 4(gene name synonym)	psi-mi:caf16_yeast(display_long)|uniprotkb:CAF16(gene name)|psi-mi:CAF16(display_short)|uniprotkb:YFL028C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11531863|imex:IM-24995-997	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006712860.1|refseq:NP_001004720.1|refseq:NP_003572.2|ensembl:ENSG00000071051(gene)|ensembl:ENST00000233154(transcript)|ensembl:ENST00000393349(transcript)|go:"GO:0001771"(immunological synapse formation)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0007015"(actin filament organization)|go:"GO:0007165"(signal transduction)|go:"GO:0007172"(signal complex assembly)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007176"(regulation of epidermal growth factor-activated receptor activity)|go:"GO:0008093"(cytoskeletal anchor activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0012506"(vesicle membrane)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016477"(cell migration)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0036493"(positive regulation of translation in response to endoplasmic reticulum stress)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042110"(T cell activation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0060996"(dendritic spine development)|go:"GO:0097110"(scaffold protein binding)|go:"GO:1902237"(positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903898"(negative regulation of PERK-mediated unfolded protein response)|go:"GO:1903912"(negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation)|go:"GO:1990441"(negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR017304(Cytoplasmic, NCK)|interpro:IPR028524|interpro:IPR035559|interpro:IPR035560|interpro:IPR035561|interpro:IPR035883|interpro:IPR036028|interpro:IPR036860|mint:O43639|rcsb pdb:1U5S|rcsb pdb:1WX6|rcsb pdb:1Z3K|rcsb pdb:2B86|rcsb pdb:2CIA|rcsb pdb:2FRW|rcsb pdb:2FRY|rcsb pdb:2JXB|rcsb pdb:4E6R|reactome:R-HSA-186763|reactome:R-HSA-373753|reactome:R-HSA-3928664|reactome:R-HSA-428540|reactome:R-HSA-4420097|reactome:R-HSA-8985801|reactome:R-HSA-9013420|reactome:R-HSA-9013424|refseq:XP_016860592.1|refseq:XP_016860593.1|refseq:XP_016860594.1|refseq:XP_011510293.1|entrezgene/locuslink:8440(identity)	refseq:NP_116625.1|sgd:S000001866|dip:DIP-5946N|ensemblfungi:YFL028C(gene)|ensemblfungi:YFL028C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0030014"(CCR4-NOT complex)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR027417|sgd:YFL028C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:WV9nJ78Im/ga5KQlRuSN2ODzWpQ9606	rogid:TEaj2ClpUSgtlaILtvQi9v5zB6A559292	intact-crc:CABD0F96F0459483|rigid:GAqQ92YJyTpMzbs4uDUGVOhHZZ0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P43592	uniprotkb:Q8N6Y0	intact:EBI-22932|uniprotkb:D6VTN8|ensemblfungi:YFR008W	intact:EBI-739895|uniprotkb:Q8NBX7|uniprotkb:Q96KH3|uniprotkb:Q9BYI8|uniprotkb:A8K7L6|uniprotkb:B2RCR9|ensembl:ENSP00000252597	psi-mi:far7_yeast(display_long)|uniprotkb:YFR008W(locus name)|uniprotkb:FAR7(gene name)|psi-mi:FAR7(display_short)	psi-mi:usbp1_human(display_long)|uniprotkb:USHBP1(gene name)|psi-mi:USHBP1(display_short)|uniprotkb:MCC-2(gene name synonym)|uniprotkb:AIE-75-binding protein(gene name synonym)|uniprotkb:AIEBP(gene name synonym)|uniprotkb:MCC2(gene name synonym)|uniprotkb:Mutated in colon cancer protein 2(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11531899|imex:IM-24995-1001	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000001904|refseq:NP_116663.1|dip:DIP-1315N|mint:P43592|ensemblfungi:YFR008W(gene)|ensemblfungi:YFR008W_mRNA(transcript)|go:"GO:0000321"(re-entry into mitotic cell cycle after pheromone arrest)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|sgd:YFR008W(identity)	refseq:NP_001284632.1|refseq:NP_114147.2|refseq:NP_001308346.1|ensembl:ENSG00000130307(gene)|ensembl:ENST00000252597(transcript)|go:"GO:0030165"(PDZ domain binding)|interpro:IPR019536|interpro:IPR040171|entrezgene/locuslink:83878(identity)	-	crc64:81156978FF7AAD54	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:RB7IaPAzOtEtryalHHz8psxOYqw559292	rogid:vY1qx73Ju/z7WDu6k1kd10ZDVRo9606	intact-crc:857EE5E457DD5305|rigid:SHiwDECj2vArFtny+DqMP2mvmOI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P43592	uniprotkb:P19012	intact:EBI-22932|uniprotkb:D6VTN8|ensemblfungi:YFR008W	intact:EBI-739566|uniprotkb:Q53XV8|uniprotkb:Q9BUG4|uniprotkb:B3KQY1|uniprotkb:B3KRA2|uniprotkb:E0CX14|ensembl:ENSP00000254043|ensembl:ENSP00000377546	psi-mi:far7_yeast(display_long)|uniprotkb:YFR008W(locus name)|uniprotkb:FAR7(gene name)|psi-mi:FAR7(display_short)	psi-mi:k1c15_human(display_long)|uniprotkb:KRT15(gene name)|psi-mi:KRT15(display_short)|uniprotkb:KRTB(gene name synonym)|uniprotkb:Cytokeratin-15(gene name synonym)|uniprotkb:Keratin-15(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11531890|imex:IM-24995-1000	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000001904|refseq:NP_116663.1|dip:DIP-1315N|mint:P43592|ensemblfungi:YFR008W(gene)|ensemblfungi:YFR008W_mRNA(transcript)|go:"GO:0000321"(re-entry into mitotic cell cycle after pheromone arrest)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|sgd:YFR008W(identity)	refseq:NP_002266.2|ensembl:ENSG00000171346(gene)|ensembl:ENST00000254043(transcript)|ensembl:ENST00000393976(transcript)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0008544"(epidermis development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097110"(scaffold protein binding)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR039008|mint:P19012|reactome:R-HSA-6805567|reactome:R-HSA-6809371|entrezgene/locuslink:3866(identity)	-	crc64:81156978FF7AAD54	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:RB7IaPAzOtEtryalHHz8psxOYqw559292	rogid:WrZQBYQvrWcfrR5ojWXrXp6spPE9606	intact-crc:2879B6674FC1723F|rigid:iFW+ndIy4CRKN6qrfc80CuyYFAE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40123	uniprotkb:P46680	intact:EBI-1051165|uniprotkb:Q6IAY2|uniprotkb:B2R5Y3|intact:EBI-11045298|uniprotkb:B7Z1C4|uniprotkb:B7Z214|ensembl:ENSP00000229922	intact:EBI-2406|uniprotkb:D6VZR5|ensemblfungi:YMR092C	psi-mi:cap2_human(display_long)|uniprotkb:CAP2(gene name)|psi-mi:CAP2(display_short)	psi-mi:aip1_yeast(display_long)|uniprotkb:AIP1(gene name)|psi-mi:AIP1(display_short)|uniprotkb:YM9582.17C(orf name)|uniprotkb:YMR092C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11531941|imex:IM-24995-1005	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006357.1|ensembl:ENSG00000112186(gene)|ensembl:ENST00000229922(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007165"(signal transduction)|go:"GO:0007190"(activation of adenylate cyclase activity)|go:"GO:0008179"(adenylate cyclase binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0042802"(identical protein binding)|go:"GO:0045761"(regulation of adenylate cyclase activity)|interpro:IPR001837(Adenylate cyclase-associated CAP)|interpro:IPR006599(CARP motif)|interpro:IPR013912(Adenylate cyclase-associated CAP,  C-terminal)|interpro:IPR013992(Adenylate cyclase-associated CAP, N-terminal)|interpro:IPR016098(Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal)|interpro:IPR017901|interpro:IPR018106|interpro:IPR028417|interpro:IPR028418|interpro:IPR036222|interpro:IPR036223|reactome:R-HSA-428890|go:"GO:0005886"(plasma membrane)|entrezgene/locuslink:10486(identity)	refseq:NP_013810.1|sgd:S000004698|reactome:R-SCE-114608|dip:DIP-890N|ensemblfungi:YMR092C(gene)|ensemblfungi:YMR092C_mRNA(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005884"(actin filament)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030479"(actin cortical patch)|go:"GO:0030836"(positive regulation of actin filament depolymerization)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032466"(negative regulation of cytokinesis)|go:"GO:0043332"(mating projection tip)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|rcsb pdb:1PGU|rcsb pdb:1PI6|sgd:YMR092C(identity)	-	-	crc64:B8340BF68DD08257	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:+B9t0sirXq7xJD3kZIlab7KBR9Y9606	rogid:TwLC/U+xqc7crYws+782F2f1rEo559292	intact-crc:27BD70E15D721F11|rigid:zfnwVDYx+4fpyXqpylfzXnZz11k	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UL45	uniprotkb:P46678	intact:EBI-465781|ensembl:ENSP00000220531	intact:EBI-19164|uniprotkb:D6W1E0|ensemblfungi:YNL039W	psi-mi:bl1s6_human(display_long)|uniprotkb:BLOC1S6(gene name)|psi-mi:BLOC1S6(display_short)|uniprotkb:PA(gene name synonym)|uniprotkb:PLDN(gene name synonym)|uniprotkb:Pallid protein homolog(gene name synonym)|uniprotkb:Pallidin(gene name synonym)|uniprotkb:Syntaxin 13-interacting protein(gene name synonym)	psi-mi:tfc5_yeast(display_long)|uniprotkb:TFIIIB90(gene name synonym)|uniprotkb:BDP1(gene name)|psi-mi:BDP1(display_short)|uniprotkb:TFC5(gene name synonym)|uniprotkb:YNL039W(locus name)|uniprotkb:N2682(orf name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11531932|imex:IM-24995-1004	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000104164(gene)|ensembl:ENST00000220531(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0007596"(blood coagulation)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0016081"(synaptic vesicle docking)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030133"(transport vesicle)|go:"GO:0030318"(melanocyte differentiation)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0032402"(melanosome transport)|go:"GO:0032438"(melanosome organization)|go:"GO:0032816"(positive regulation of natural killer cell activation)|go:"GO:0033299"(secretion of lysosomal enzymes)|go:"GO:0035646"(endosome to melanosome transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046907"(intracellular transport)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0050942"(positive regulation of pigment cell differentiation)|go:"GO:0051015"(actin filament binding)|go:"GO:0061025"(membrane fusion)|go:"GO:0098793"(presynapse)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR017242(BLOC-1 complex, pallidin subunit)|go:"GO:0031175"(neuron projection development)|interpro:IPR028119|mint:Q9UL45|reactome:R-HSA-432722|refseq:NP_036520.1|entrezgene/locuslink:26258(identity)	sgd:S000004984|ensemblfungi:YNL039W(gene)|ensemblfungi:YNL039W_mRNA(transcript)|go:"GO:0000126"(transcription factor TFIIIB complex)|go:"GO:0000995"(RNA polymerase III general transcription initiation factor activity)|go:"GO:0001112"(DNA-templated transcription open complex formation)|go:"GO:0001156"(TFIIIC-class transcription factor complex binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0070896"(positive regulation of transposon integration)|go:"GO:0070898"(RNA polymerase III preinitiation complex assembly)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017174(Transcription factor IIIB, Bdp1 subunit, fungi)|interpro:IPR039467|rcsb pdb:6CNB|rcsb pdb:6CNC|rcsb pdb:6CND|rcsb pdb:6CNF|rcsb pdb:6EU0|rcsb pdb:6F40|rcsb pdb:6F41|rcsb pdb:6F42|rcsb pdb:6F44|reactome:R-SCE-76061|reactome:R-SCE-76066|refseq:NP_014359.3|dip:DIP-964N|mint:P46678|sgd:YNL039W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:s5/ikwpqtA8Mm8gMd6ttfmBBKSA9606	rogid:UHI3UvDK3qlouZn4JrhYcxOhr1s559292	intact-crc:2042850ADCE43C76|rigid:DTzuh9oFssqrZFkUaM1psx1rxzQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9P1Z2	uniprotkb:P46678	intact:EBI-749920|uniprotkb:B3KVA8|uniprotkb:Q6FI59|uniprotkb:Q71RC3|uniprotkb:Q86WF8|uniprotkb:Q96JU3|uniprotkb:Q9H090|intact:EBI-2558801|ensembl:ENSP00000449960	intact:EBI-19164|uniprotkb:D6W1E0|ensemblfungi:YNL039W	psi-mi:caco1_human(display_long)|uniprotkb:CALCOCO1(gene name)|psi-mi:CALCOCO1(display_short)|uniprotkb:KIAA1536(gene name synonym)|uniprotkb:Calphoglin(gene name synonym)|uniprotkb:Sarcoma antigen NY-SAR-3(gene name synonym)|uniprotkb:Coiled-coil coactivator protein(gene name synonym)|uniprotkb:PP13275(orf name)|uniprotkb:UNQ2436/PRO4996(orf name)	psi-mi:tfc5_yeast(display_long)|uniprotkb:TFIIIB90(gene name synonym)|uniprotkb:BDP1(gene name)|psi-mi:BDP1(display_short)|uniprotkb:TFC5(gene name synonym)|uniprotkb:YNL039W(locus name)|uniprotkb:N2682(orf name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11531923|imex:IM-24995-1003	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001137154.1|refseq:NP_065949.1|refseq:XP_016875196.1|dip:DIP-47322N|ensembl:ENSG00000012822(gene)|ensembl:ENST00000550804(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0007165"(signal transduction)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0070016"(armadillo repeat domain binding)|interpro:IPR012852(Coiled-coil transcriptional coactivator-like)|interpro:IPR041611|interpro:IPR041641|mint:Q9P1Z2|entrezgene/locuslink:57658(identity)	sgd:S000004984|ensemblfungi:YNL039W(gene)|ensemblfungi:YNL039W_mRNA(transcript)|go:"GO:0000126"(transcription factor TFIIIB complex)|go:"GO:0000995"(RNA polymerase III general transcription initiation factor activity)|go:"GO:0001112"(DNA-templated transcription open complex formation)|go:"GO:0001156"(TFIIIC-class transcription factor complex binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0070896"(positive regulation of transposon integration)|go:"GO:0070898"(RNA polymerase III preinitiation complex assembly)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017174(Transcription factor IIIB, Bdp1 subunit, fungi)|interpro:IPR039467|rcsb pdb:6CNB|rcsb pdb:6CNC|rcsb pdb:6CND|rcsb pdb:6CNF|rcsb pdb:6EU0|rcsb pdb:6F40|rcsb pdb:6F41|rcsb pdb:6F42|rcsb pdb:6F44|reactome:R-SCE-76061|reactome:R-SCE-76066|refseq:NP_014359.3|dip:DIP-964N|mint:P46678|sgd:YNL039W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:4M9Qyq+7GZ1w2UAN6k0ntGQNTvw9606	rogid:UHI3UvDK3qlouZn4JrhYcxOhr1s559292	intact-crc:9B5305D141BF30A8|rigid:jQCvoloeNiBRCXgyf7rudSND1Ws	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P43618	uniprotkb:O95198	intact:EBI-23036|uniprotkb:D6VTS9|uniprotkb:Q6B2K8|ensemblfungi:YFR046C	intact:EBI-746999|uniprotkb:B2RD18|uniprotkb:Q8N484|uniprotkb:Q8TBH5|uniprotkb:A6NCM7|uniprotkb:B4DFH7|uniprotkb:F5H6M3|ensembl:ENSP00000226725	psi-mi:cenpt_yeast(display_long)|uniprotkb:CNN1(gene name)|psi-mi:CNN1(display_short)|uniprotkb:Co-purified with NNF1 protein 1(gene name synonym)|uniprotkb:CENP-T homolog(gene name synonym)|uniprotkb:Constitutive centromere-associated network protein CNN1(gene name synonym)|uniprotkb:YFR046C(locus name)	psi-mi:klhl2_human(display_long)|uniprotkb:Actin-binding protein Mayven(gene name synonym)|uniprotkb:KLHL2(gene name)|psi-mi:KLHL2(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11531914|imex:IM-24995-1002	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000001942|refseq:NP_116704.1|dip:DIP-5186N|ensemblfungi:YFR046C(gene)|ensemblfungi:YFR046C_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0019237"(centromeric DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051301"(cell division)|go:"GO:1901720"(negative regulation of NMS complex assembly)|rcsb pdb:4GEQ|rcsb pdb:6WUC|rcsb pdb:6YPC|sgd:YFR046C(identity)	refseq:NP_001154993.1|refseq:NP_001154994.1|refseq:NP_009177.3|refseq:NP_001317952.1|refseq:NP_001317953.1|refseq:XP_016863165.1|ensembl:ENSG00000109466(gene)|ensembl:ENST00000226725(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030027"(lamellipodium)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR017096(Kelch-like protein, gigaxonin)|interpro:IPR044072|mint:O95198|rcsb pdb:2XN4|rcsb pdb:4CHB|reactome:R-HSA-8951664|reactome:R-HSA-983168|go:"GO:0042802"(identical protein binding)|entrezgene/locuslink:11275(identity)	-	crc64:48CEEC087A056D42	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Pkvt7uOWT2WqZlcWh8NeZH67Mvs559292	rogid:tFegR2lJZccRqs4qUjdT3PNjNnk9606	intact-crc:7B6F20399C467E25|rigid:r9OW5JqnvYns5Kl5S88NI9Ly1nM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P63261	uniprotkb:P46680	intact:EBI-351292|uniprotkb:P02571|uniprotkb:P14104|uniprotkb:P99022|uniprotkb:Q5U032|uniprotkb:Q96E67|uniprotkb:A8K7C2|ensembl:ENSP00000505060|ensembl:ENSP00000505193|ensembl:ENSP00000505235|ensembl:ENSP00000506126|ensembl:ENSP00000506201|ensembl:ENSP00000506253|ensembl:ENSP00000458162|ensembl:ENSP00000458435|ensembl:ENSP00000459119|ensembl:ENSP00000459124|ensembl:ENSP00000460464|ensembl:ENSP00000460660|ensembl:ENSP00000461672|ensembl:ENSP00000466346|ensembl:ENSP00000477968	intact:EBI-2406|uniprotkb:D6VZR5|ensemblfungi:YMR092C	psi-mi:actg_human(display_long)|uniprotkb:ACTG1(gene name)|psi-mi:ACTG1(display_short)|uniprotkb:ACTG(gene name synonym)|uniprotkb:Gamma-actin(gene name synonym)	psi-mi:aip1_yeast(display_long)|uniprotkb:AIP1(gene name)|psi-mi:AIP1(display_short)|uniprotkb:YM9582.17C(orf name)|uniprotkb:YMR092C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11531960|imex:IM-24995-1007	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001186883.1|refseq:NP_001605.1|ensembl:ENST00000570382(transcript)|ensembl:ENSG00000184009(gene)|ensembl:ENST00000571721(transcript)|ensembl:ENST00000573283(transcript)|ensembl:ENST00000575087(transcript)|ensembl:ENST00000575659(transcript)|ensembl:ENST00000575842(transcript)|ensembl:ENST00000575994(transcript)|ensembl:ENST00000576544(transcript)|ensembl:ENST00000615544(transcript)|ensembl:ENST00000679480(transcript)|ensembl:ENST00000679778(transcript)|ensembl:ENST00000680227(transcript)|ensembl:ENST00000680727(transcript)|ensembl:ENST00000681052(transcript)|ensembl:ENST00000681842(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0001895"(retina homeostasis)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005522"(profilin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0030016"(myofibril)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031941"(filamentous actin)|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0044305"(calyx of Held)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0051492"(regulation of stress fiber assembly)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070527"(platelet aggregation)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0072562"(blood microparticle)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0097433"(dense body)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098973"(structural constituent of postsynaptic actin cytoskeleton)|go:"GO:0120192"(tight junction assembly)|go:"GO:0120220"(basal body patch)|go:"GO:0150111"(regulation of transepithelial transport)|go:"GO:1902396"(protein localization to bicellular tight junction)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P63261|rcsb pdb:5JLH|rcsb pdb:6CXI|rcsb pdb:6CXJ|rcsb pdb:6G2T|rcsb pdb:6V62|rcsb pdb:6V63|rcsb pdb:6WK1|rcsb pdb:6WK2|reactome:R-HSA-1445148|reactome:R-HSA-190873|reactome:R-HSA-196025|reactome:R-HSA-2029482|reactome:R-HSA-3928662|reactome:R-HSA-3928665|reactome:R-HSA-418990|reactome:R-HSA-437239|reactome:R-HSA-4420097|reactome:R-HSA-445095|reactome:R-HSA-446353|reactome:R-HSA-5626467|reactome:R-HSA-5663213|reactome:R-HSA-5663220|reactome:R-HSA-5674135|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8856828|reactome:R-HSA-9013418|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9662360|reactome:R-HSA-9662361|reactome:R-HSA-9664422|entrezgene/locuslink:71(identity)	refseq:NP_013810.1|sgd:S000004698|reactome:R-SCE-114608|dip:DIP-890N|ensemblfungi:YMR092C(gene)|ensemblfungi:YMR092C_mRNA(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005884"(actin filament)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030479"(actin cortical patch)|go:"GO:0030836"(positive regulation of actin filament depolymerization)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032466"(negative regulation of cytokinesis)|go:"GO:0043332"(mating projection tip)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|rcsb pdb:1PGU|rcsb pdb:1PI6|sgd:YMR092C(identity)	-	-	crc64:B8340BF68DD08257	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:B2OOsE06lTfo90H3g8tlmUJQ7cY9606	rogid:TwLC/U+xqc7crYws+782F2f1rEo559292	intact-crc:1FA8AF954FB11D4A|rigid:cPDgvvGA0FJRLriPJYA+vCDTtGQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P46680	uniprotkb:P60709	intact:EBI-2406|uniprotkb:D6VZR5|ensemblfungi:YMR092C	intact:EBI-353944|uniprotkb:P02570|uniprotkb:P70514|uniprotkb:P99021|uniprotkb:Q11211|uniprotkb:Q64316|uniprotkb:Q75MN2|uniprotkb:Q96B34|uniprotkb:Q96HG5|ensembl:ENSP00000494269|ensembl:ENSP00000494750|ensembl:ENSP00000495995|ensembl:ENSP00000501862|ensembl:ENSP00000502821	psi-mi:aip1_yeast(display_long)|uniprotkb:AIP1(gene name)|psi-mi:AIP1(display_short)|uniprotkb:YM9582.17C(orf name)|uniprotkb:YMR092C(locus name)	psi-mi:actb_human(display_long)|uniprotkb:ACTB(gene name)|psi-mi:ACTB(display_short)|uniprotkb:Beta-actin(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11531950|imex:IM-24995-1006	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013810.1|sgd:S000004698|reactome:R-SCE-114608|dip:DIP-890N|ensemblfungi:YMR092C(gene)|ensemblfungi:YMR092C_mRNA(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005884"(actin filament)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030479"(actin cortical patch)|go:"GO:0030836"(positive regulation of actin filament depolymerization)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032466"(negative regulation of cytokinesis)|go:"GO:0043332"(mating projection tip)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|rcsb pdb:1PGU|rcsb pdb:1PI6|sgd:YMR092C(identity)	refseq:NP_001092.1|ensembl:ENSG00000075624(gene)|ensembl:ENST00000493945(transcript)|ensembl:ENST00000642480(transcript)|ensembl:ENST00000646664(transcript)|ensembl:ENST00000674681(transcript)|ensembl:ENST00000675515(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000785"(chromatin)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0001895"(retina homeostasis)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007409"(axonogenesis)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019894"(kinesin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0022898"(regulation of transmembrane transporter activity)|go:"GO:0030027"(lamellipodium)|go:"GO:0030424"(axon)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0030957"(Tat protein binding)|go:"GO:0031982"(vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034333"(adherens junction assembly)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043044"|go:"GO:0043296"(apical junction complex)|go:"GO:0044305"(calyx of Held)|go:"GO:0045176"(apical protein localization)|go:"GO:0045202"(synapse)|go:"GO:0048156"(tau protein binding)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048870"(cell motility)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051621"(regulation of norepinephrine uptake)|go:"GO:0051623"(positive regulation of norepinephrine uptake)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070160"(tight junction)|go:"GO:0070527"(platelet aggregation)|reactome:R-HSA-4420097|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0072562"(blood microparticle)|go:"GO:0072749"(cellular response to cytochalasin B)|go:"GO:0097433"(dense body)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098973"(structural constituent of postsynaptic actin cytoskeleton)|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0150111"(regulation of transepithelial transport)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P60709|rcsb pdb:3BYH|rcsb pdb:3D2U|rcsb pdb:3J82|rcsb pdb:3LUE|rcsb pdb:6ANU|rcsb pdb:6ICT|rcsb pdb:6ICV|rcsb pdb:6LTJ|rcsb pdb:6MBJ|rcsb pdb:6MBK|rcsb pdb:6MBL|rcsb pdb:6NBW|rcsb pdb:6OX0|rcsb pdb:6OX1|rcsb pdb:6OX2|rcsb pdb:6OX3|rcsb pdb:6OX4|rcsb pdb:6OX5|rcsb pdb:6V62|rcsb pdb:6V63|rcsb pdb:6WK1|rcsb pdb:6WK2|rcsb pdb:7AS4|reactome:R-HSA-1445148|reactome:R-HSA-190873|reactome:R-HSA-196025|reactome:R-HSA-2029482|reactome:R-HSA-3214847|reactome:R-HSA-389957|reactome:R-HSA-390450|reactome:R-HSA-3928662|reactome:R-HSA-3928665|reactome:R-HSA-418990|reactome:R-HSA-437239|reactome:R-HSA-446353|reactome:R-HSA-5250924|reactome:R-HSA-5626467|reactome:R-HSA-5663213|reactome:R-HSA-5663220|reactome:R-HSA-5674135|reactome:R-HSA-5689603|reactome:R-HSA-5696394|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8856828|reactome:R-HSA-9035034|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9662360|reactome:R-HSA-9662361|reactome:R-HSA-9664422|reactome:R-HSA-983231|reactome:R-HSA-445095|dip:DIP-29686N|entrezgene/locuslink:60(identity)	-	crc64:B8340BF68DD08257	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:TwLC/U+xqc7crYws+782F2f1rEo559292	rogid:Hoge1B8Pn56kvbNTpkSLsQuHwRc9606	intact-crc:2D0E7252BB960E03|rigid:QcyuVysqGGcjywTrYed9rsrPJ28	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P46680	uniprotkb:Q9Y281	intact:EBI-2406|uniprotkb:D6VZR5|ensemblfungi:YMR092C	intact:EBI-351218|uniprotkb:G3V5P4|ensembl:ENSP00000298159|ensembl:ENSP00000340635|ensembl:ENSP00000500375|ensembl:ENSP00000500532	psi-mi:aip1_yeast(display_long)|uniprotkb:AIP1(gene name)|psi-mi:AIP1(display_short)|uniprotkb:YM9582.17C(orf name)|uniprotkb:YMR092C(locus name)	psi-mi:cof2_human(display_long)|uniprotkb:CFL2(gene name)|psi-mi:CFL2(display_short)|uniprotkb:Cofilin, muscle isoform(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11531970|imex:IM-24995-1008	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013810.1|sgd:S000004698|reactome:R-SCE-114608|dip:DIP-890N|ensemblfungi:YMR092C(gene)|ensemblfungi:YMR092C_mRNA(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005884"(actin filament)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030479"(actin cortical patch)|go:"GO:0030836"(positive regulation of actin filament depolymerization)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032466"(negative regulation of cytokinesis)|go:"GO:0043332"(mating projection tip)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|rcsb pdb:1PGU|rcsb pdb:1PI6|sgd:YMR092C(identity)	refseq:NP_068733.1|refseq:NP_619579.1|refseq:XP_011534665.1|refseq:NP_001230574.1|dip:DIP-33178N|ensembl:ENSG00000165410(gene)|ensembl:ENST00000298159(transcript)|ensembl:ENST00000341223(transcript)|ensembl:ENST00000672163(transcript)|ensembl:ENST00000672517(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016363"(nuclear matrix)|go:"GO:0030018"(Z disc)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030043"(actin filament fragmentation)|go:"GO:0030836"(positive regulation of actin filament depolymerization)|go:"GO:0031674"(I band)|go:"GO:0045214"(sarcomere organization)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0048870"(cell motility)|go:"GO:0051014"(actin filament severing)|go:"GO:0051015"(actin filament binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002108(Actin-binding, cofilin/tropomyosin type)|interpro:IPR017904|interpro:IPR029006|mint:Q9Y281|entrezgene/locuslink:1073(identity)	-	crc64:B8340BF68DD08257	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:TwLC/U+xqc7crYws+782F2f1rEo559292	rogid:HwYoUPZRkuRzqMLvuQctwNCOREA9606	intact-crc:859358EAC6CABAF2|rigid:3XBdOAwfyGwKG/zP3T5emtfdSgk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P46682	uniprotkb:P61289	intact:EBI-2213|uniprotkb:D6VV40|ensemblfungi:YGR261C	intact:EBI-355546|uniprotkb:O35563|uniprotkb:P97373|uniprotkb:Q12920|uniprotkb:Q13172|uniprotkb:Q9BQD9|uniprotkb:A8K9A3|ensembl:ENSP00000466794	psi-mi:ap3b_yeast(display_long)|uniprotkb:APL6(gene name)|psi-mi:APL6(display_short)|uniprotkb:YKS5(gene name synonym)|uniprotkb:YGR261C(locus name)|uniprotkb:G9331(orf name)|uniprotkb:Beta-3-adaptin(gene name synonym)|uniprotkb:Clathrin assembly protein complex 3 beta large chain(gene name synonym)|uniprotkb:Clathrin assembly protein large beta chain(gene name synonym)|uniprotkb:Adaptor-related protein complex 3 subunit beta(gene name synonym)	psi-mi:psme3_human(display_long)|uniprotkb:PSME3(gene name)|psi-mi:PSME3(display_short)|uniprotkb:Proteasome activator 28 subunit gamma(gene name synonym)|uniprotkb:Activator of multicatalytic protease subunit 3(gene name synonym)|uniprotkb:11S regulator complex subunit gamma(gene name synonym)|uniprotkb:Ki nuclear autoantigen(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11531979|imex:IM-24995-1009	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003493|refseq:NP_011777.3|ensemblfungi:YGR261C(gene)|ensemblfungi:YGR261C_mRNA(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030123"(AP-3 adaptor complex)|go:"GO:0030665"(clathrin-coated vesicle membrane)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026739|interpro:IPR026740|dip:DIP-2684N|mint:P46682|sgd:YGR261C(identity)	refseq:NP_005780.2|refseq:NP_789839.1|ensembl:ENSG00000131467(gene)|ensembl:ENST00000590720(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0008537"(proteasome activator complex)|go:"GO:0010950"(positive regulation of endopeptidase activity)|go:"GO:0016020"(membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0061133"(endopeptidase activator activity)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0097371"(MDM2/MDM4 family protein binding)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR003185(Proteasome activator pa28, REG alpha subunit)|interpro:IPR003186(Proteasome activator pa28, REG beta subunit)|interpro:IPR009077(Proteasome activator pa28, REG alpha/beta subunit)|interpro:IPR036252|interpro:IPR036996|interpro:IPR036997|mint:P61289|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|entrezgene/locuslink:10197(identity)	-	crc64:475DA3A4F6E68E97	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:J+pCwMtq9Jhj24BeTVg7XpCHmKE559292	rogid:6EQY2Kj3Juf++m4eBDzPWMgbC2k9606	intact-crc:BA02F2D59CE62FCF|rigid:DbAIVQbJkO3NIpxeEDw6z/iVMcw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P46682	uniprotkb:Q8NHQ1	intact:EBI-2213|uniprotkb:D6VV40|ensemblfungi:YGR261C	intact:EBI-739624|ensembl:ENSP00000264982|ensembl:ENSP00000419231|uniprotkb:Q96B31|uniprotkb:Q9H2C3|uniprotkb:Q9H2Z1|uniprotkb:Q9H940|uniprotkb:D3DNE9|uniprotkb:B7Z5I8|uniprotkb:B7Z7E8|uniprotkb:F5GZX8	psi-mi:ap3b_yeast(display_long)|uniprotkb:APL6(gene name)|psi-mi:APL6(display_short)|uniprotkb:YKS5(gene name synonym)|uniprotkb:YGR261C(locus name)|uniprotkb:G9331(orf name)|uniprotkb:Beta-3-adaptin(gene name synonym)|uniprotkb:Clathrin assembly protein complex 3 beta large chain(gene name synonym)|uniprotkb:Clathrin assembly protein large beta chain(gene name synonym)|uniprotkb:Adaptor-related protein complex 3 subunit beta(gene name synonym)	psi-mi:cep70_human(display_long)|uniprotkb:CEP70(gene name)|psi-mi:CEP70(display_short)|uniprotkb:BITE(gene name synonym)|uniprotkb:p10-binding protein(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11531988|imex:IM-24995-1010	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003493|refseq:NP_011777.3|ensemblfungi:YGR261C(gene)|ensemblfungi:YGR261C_mRNA(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030123"(AP-3 adaptor complex)|go:"GO:0030665"(clathrin-coated vesicle membrane)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026739|interpro:IPR026740|dip:DIP-2684N|mint:P46682|sgd:YGR261C(identity)	ensembl:ENSG00000114107(gene)|ensembl:ENST00000264982(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|interpro:IPR019734|interpro:IPR037692|mint:Q8NHQ1|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|ensembl:ENST00000484888(transcript)|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_077817.2|refseq:XP_016862764.1|refseq:NP_001275893.1|refseq:NP_001275894.1|refseq:NP_001275895.1|refseq:NP_001275896.1|refseq:NP_001307527.1|refseq:NP_001307529.1|entrezgene/locuslink:80321(identity)	-	crc64:475DA3A4F6E68E97	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:J+pCwMtq9Jhj24BeTVg7XpCHmKE559292	rogid:S4yveQWcvdVtAUX65gqrJ5Dv0Mc9606	intact-crc:14D0745B56186F1D|rigid:M8Dkr3+t2NvMQ21DMTr7naSknDo	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UJV3-2	uniprotkb:P46945	intact:EBI-10172526|ensembl:ENSP00000413976	intact:EBI-11531997|uniprotkb:D6VTX6|ensemblfungi:YGL176C	psi-mi:q9ujv3-2(display_long)|uniprotkb:RING-type E3 ubiquitin transferase MID2(gene name synonym)|uniprotkb:FXY2(gene name synonym)|uniprotkb:Midin-2(gene name synonym)|uniprotkb:Midline defect 2(gene name synonym)|uniprotkb:Midline-2(gene name synonym)|uniprotkb:RING finger protein 60(gene name synonym)|uniprotkb:RNF60(gene name synonym)|uniprotkb:TRIM1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 1(gene name synonym)|uniprotkb:MID2(gene name)|psi-mi:MID2(display_short)	psi-mi:ygs6_yeast(display_long)|uniprotkb:G1636(orf name)|uniprotkb:YGL176C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11531999|imex:IM-24995-1011	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-751983(isoform-parent)|uniprotkb:Q9UJV3-2(isoform-parent)|ensembl:ENSG00000080561(gene)|ensembl:ENST00000443968(transcript)|entrezgene/locuslink:11043(identity)	refseq:NP_011339.1|sgd:S000003144|ensemblfungi:YGL176C(gene)|ensemblfungi:YGL176C_mRNA(transcript)|sgd:YGL176C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/03/16	rogid:/FJ+V2H7SaWon7caUWkEkmHFVxQ9606	rogid:vWpHYgTdiHjJQSg5gUHb94U3Uhk559292	intact-crc:5B1BC9E4A59BFE27|rigid:eG8fkGozVkfJ5tFaS2KYEDcONnA	false	sufficient binding region:21-705	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P20807-4	uniprotkb:P46948	intact:EBI-11532021|ensembl:ENSP00000380384	intact:EBI-1788|uniprotkb:D6VUX7|ensemblfungi:YGR195W	psi-mi:p20807-4(display_long)|uniprotkb:CAPN3(gene name)|psi-mi:CAPN3(display_short)|uniprotkb:CANP3(gene name synonym)|uniprotkb:CANPL3(gene name synonym)|uniprotkb:Calcium-activated neutral proteinase 3(gene name synonym)|uniprotkb:Calpain L3(gene name synonym)|uniprotkb:Calpain p94(gene name synonym)|uniprotkb:Muscle-specific calcium-activated neutral protease 3(gene name synonym)|uniprotkb:NCL1(gene name synonym)|uniprotkb:New calpain 1(gene name synonym)	psi-mi:rrp41_yeast(display_long)|uniprotkb:SKI6(gene name)|psi-mi:SKI6(display_short)|uniprotkb:YGR195W(locus name)|uniprotkb:G7587(orf name)|uniprotkb:ECM20(gene name synonym)|uniprotkb:Ribosomal RNA-processing protein 41(gene name synonym)|uniprotkb:Superkiller protein 6(gene name synonym)|uniprotkb:Extracellular mutant protein 20(gene name synonym)|uniprotkb:RRP41(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11532025|imex:IM-24995-1013	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-5655000(isoform-parent)|uniprotkb:P20807-4(isoform-parent)|ensembl:ENSG00000092529(gene)|ensembl:ENST00000397200(transcript)|entrezgene/locuslink:825(identity)	sgd:S000003427|refseq:NP_011711.3|dip:DIP-2083N|mint:P46948|ensemblfungi:YGR195W(gene)|ensemblfungi:YGR195W_mRNA(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034473"(U1 snRNA 3'-end processing)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0034476"(U5 snRNA 3'-end processing)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071039"(nuclear polyadenylation-dependent CUT catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345|rcsb pdb:2WP8|rcsb pdb:4IFD|rcsb pdb:4OO1|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5G06|rcsb pdb:5JEA|rcsb pdb:5K36|rcsb pdb:5OKZ|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-429958|reactome:R-SCE-450385|reactome:R-SCE-450513|reactome:R-SCE-6791226|sgd:YGR195W(identity)	-	-	crc64:C80EFFB528A43044	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:6TrGg2jigHr0xYLsxBNCLjAl3J89606	rogid:I7vEo0EUB1jZO+3v12H0LwVbgmo559292	intact-crc:1CDFC4A89B6B636C|rigid:qR8dwfZsFl11ZR3gc4ETCIgmcEc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q08379	uniprotkb:P46948	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	intact:EBI-1788|uniprotkb:D6VUX7|ensemblfungi:YGR195W	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:rrp41_yeast(display_long)|uniprotkb:SKI6(gene name)|psi-mi:SKI6(display_short)|uniprotkb:YGR195W(locus name)|uniprotkb:G7587(orf name)|uniprotkb:ECM20(gene name synonym)|uniprotkb:Ribosomal RNA-processing protein 41(gene name synonym)|uniprotkb:Superkiller protein 6(gene name synonym)|uniprotkb:Extracellular mutant protein 20(gene name synonym)|uniprotkb:RRP41(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11532010|imex:IM-24995-1012	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N|entrezgene/locuslink:2801(identity)	sgd:S000003427|refseq:NP_011711.3|dip:DIP-2083N|mint:P46948|ensemblfungi:YGR195W(gene)|ensemblfungi:YGR195W_mRNA(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034473"(U1 snRNA 3'-end processing)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0034476"(U5 snRNA 3'-end processing)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071039"(nuclear polyadenylation-dependent CUT catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345|rcsb pdb:2WP8|rcsb pdb:4IFD|rcsb pdb:4OO1|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5G06|rcsb pdb:5JEA|rcsb pdb:5K36|rcsb pdb:5OKZ|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-429958|reactome:R-SCE-450385|reactome:R-SCE-450513|reactome:R-SCE-6791226|sgd:YGR195W(identity)	-	-	crc64:C80EFFB528A43044	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2017/05/26	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	rogid:I7vEo0EUB1jZO+3v12H0LwVbgmo559292	intact-crc:872B79D459705E4A|rigid:aYVsQbvOuS0rfHAKF/pT/tJUV3E	false	sufficient binding region:383-1002	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8IYX7	uniprotkb:P46948	intact:EBI-3957636|ensembl:ENSP00000369907|intact:EBI-10174528|uniprotkb:A8K880|uniprotkb:Q5VY58	intact:EBI-1788|uniprotkb:D6VUX7|ensemblfungi:YGR195W	psi-mi:saxo1_human(display_long)|uniprotkb:SAXO1(gene name)|psi-mi:SAXO1(display_short)|uniprotkb:C9orf138(gene name synonym)|uniprotkb:FAM154A(gene name synonym)	psi-mi:rrp41_yeast(display_long)|uniprotkb:SKI6(gene name)|psi-mi:SKI6(display_short)|uniprotkb:YGR195W(locus name)|uniprotkb:G7587(orf name)|uniprotkb:ECM20(gene name synonym)|uniprotkb:Ribosomal RNA-processing protein 41(gene name synonym)|uniprotkb:Superkiller protein 6(gene name synonym)|uniprotkb:Extracellular mutant protein 20(gene name synonym)|uniprotkb:RRP41(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11532034|imex:IM-24995-1014	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000155875(gene)|ensembl:ENST00000380534(transcript)|go:"GO:0005814"(centriole)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0008017"(microtubule binding)|go:"GO:0009631"(cold acclimation)|go:"GO:0030030"(cell projection organization)|go:"GO:0031514"(motile cilium)|go:"GO:0034453"(microtubule anchoring)|go:"GO:0036064"(ciliary basal body)|go:"GO:0036126"(sperm flagellum)|go:"GO:0045724"(positive regulation of cilium assembly)|go:"GO:0050821"(protein stabilization)|go:"GO:0070417"(cellular response to cold)|interpro:IPR033336|refseq:NP_714918.2|refseq:NP_001273978.1|refseq:NP_001273979.1|entrezgene/locuslink:158297(identity)	sgd:S000003427|refseq:NP_011711.3|dip:DIP-2083N|mint:P46948|ensemblfungi:YGR195W(gene)|ensemblfungi:YGR195W_mRNA(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034473"(U1 snRNA 3'-end processing)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0034476"(U5 snRNA 3'-end processing)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071039"(nuclear polyadenylation-dependent CUT catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345|rcsb pdb:2WP8|rcsb pdb:4IFD|rcsb pdb:4OO1|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5G06|rcsb pdb:5JEA|rcsb pdb:5K36|rcsb pdb:5OKZ|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-429958|reactome:R-SCE-450385|reactome:R-SCE-450513|reactome:R-SCE-6791226|sgd:YGR195W(identity)	-	-	crc64:C80EFFB528A43044	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:34It0miSDTtv5wwJ+ERHXJzWRiQ9606	rogid:I7vEo0EUB1jZO+3v12H0LwVbgmo559292	intact-crc:CABBDE267526CED5|rigid:tnCrBQySz/SLCacRedV2TfSkLr0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9Y3Q8	uniprotkb:P46948	intact:EBI-739485|uniprotkb:A8MWR6|ensembl:ENSP00000300181|uniprotkb:A4D2C3|uniprotkb:D6W5V9	intact:EBI-1788|uniprotkb:D6VUX7|ensemblfungi:YGR195W	psi-mi:t22d4_human(display_long)|uniprotkb:TSC22D4(gene name)|psi-mi:TSC22D4(display_short)|uniprotkb:TILZ2(gene name synonym)|uniprotkb:TSC22-related-inducible leucine zipper protein 2(gene name synonym)|uniprotkb:Tsc-22-like protein THG-1(gene name synonym)|uniprotkb:THG1(gene name synonym)	psi-mi:rrp41_yeast(display_long)|uniprotkb:SKI6(gene name)|psi-mi:SKI6(display_short)|uniprotkb:YGR195W(locus name)|uniprotkb:G7587(orf name)|uniprotkb:ECM20(gene name synonym)|uniprotkb:Ribosomal RNA-processing protein 41(gene name synonym)|uniprotkb:Superkiller protein 6(gene name synonym)|uniprotkb:Extracellular mutant protein 20(gene name synonym)|uniprotkb:RRP41(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11532070|imex:IM-24995-1018	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000166925(gene)|ensembl:ENST00000300181(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006970"(response to osmotic stress)|interpro:IPR000580(TSC-22 / Dip / Bun)|interpro:IPR042553|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|refseq:NP_112197.1|refseq:NP_001289972.1|entrezgene/locuslink:81628(identity)	sgd:S000003427|refseq:NP_011711.3|dip:DIP-2083N|mint:P46948|ensemblfungi:YGR195W(gene)|ensemblfungi:YGR195W_mRNA(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034473"(U1 snRNA 3'-end processing)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0034476"(U5 snRNA 3'-end processing)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071039"(nuclear polyadenylation-dependent CUT catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345|rcsb pdb:2WP8|rcsb pdb:4IFD|rcsb pdb:4OO1|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5G06|rcsb pdb:5JEA|rcsb pdb:5K36|rcsb pdb:5OKZ|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-429958|reactome:R-SCE-450385|reactome:R-SCE-450513|reactome:R-SCE-6791226|sgd:YGR195W(identity)	-	-	crc64:C80EFFB528A43044	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:eL12cHY76zEPOXzT1HFKPSckS8Y9606	rogid:I7vEo0EUB1jZO+3v12H0LwVbgmo559292	intact-crc:64D9FE84D9FD3919|rigid:ZXtHWRBKdozAbydNT2AWOJTR0OE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P46956	uniprotkb:Q8N6L0	intact:EBI-13337|uniprotkb:E9P8T7|ensemblfungi:YJL117W|uniprotkb:D6VW67	intact:EBI-749265|uniprotkb:Q96MC3|ensembl:ENSP00000404220	psi-mi:pho86_yeast(display_long)|uniprotkb:PHO86(gene name)|psi-mi:PHO86(display_short)|uniprotkb:J0744(orf name)|uniprotkb:YJL117W(locus name)	psi-mi:kash5_human(display_long)|uniprotkb:KASH5(gene name)|psi-mi:KASH5(display_short)|uniprotkb:CCDC155(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 155(gene name synonym)|uniprotkb:KASH domain-containing protein 5(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11532079|imex:IM-24995-1019	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012418.1|sgd:S000003653|interpro:IPR024297|ensemblfungi:YJL117W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006457"(protein folding)|go:"GO:0006817"(phosphate ion transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0010966"(regulation of phosphate transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0051082"(unfolded protein binding)|ensemblfungi:YJL117W(gene)|mint:P46956|dip:DIP-2769N|sgd:YJL117W(identity)	refseq:NP_653289.3|ensembl:ENSG00000161609(gene)|ensembl:ENST00000447857(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034397"(telomere localization)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051225"(spindle assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0090172"(microtubule cytoskeleton organization involved in homologous chromosome segregation)|go:"GO:0090220"(chromosome localization to nuclear envelope involved in homologous chromosome segregation)|go:"GO:0090619"(meiotic spindle pole)|interpro:IPR011992(EF-Hand type)|interpro:IPR028168|interpro:IPR028170|interpro:IPR039508|mint:Q8N6L0|rcsb pdb:6R2I|rcsb pdb:6WMF|entrezgene/locuslink:147872(identity)	-	crc64:1CB19C9184BF1C48	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:JITWReptfMoij1Uy6y1e3Oa6dAs559292	rogid:Wl9L7AcvDHCZuKjYLn8QgGIbZTc9606	intact-crc:B05735CF992BAECD|rigid:UjXzjWJ+P5RZ9QrBKzqQGs1bp0w	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P46948	uniprotkb:Q9UKT9	intact:EBI-1788|uniprotkb:D6VUX7|ensemblfungi:YGR195W	intact:EBI-747204|uniprotkb:Q8WWQ9|uniprotkb:Q8WWR0|uniprotkb:Q8WWR1|uniprotkb:Q8WWR2|uniprotkb:Q8WWR3|uniprotkb:Q8N574|uniprotkb:B4DVV5|uniprotkb:Q69BL6|uniprotkb:Q69BL7|uniprotkb:Q69BL8|uniprotkb:Q69BL9|uniprotkb:Q69BM0|uniprotkb:Q69BM1|uniprotkb:Q69BM2|uniprotkb:Q69BM3|uniprotkb:Q69BM5|ensembl:ENSP00000344544	psi-mi:rrp41_yeast(display_long)|uniprotkb:SKI6(gene name)|psi-mi:SKI6(display_short)|uniprotkb:YGR195W(locus name)|uniprotkb:G7587(orf name)|uniprotkb:ECM20(gene name synonym)|uniprotkb:Ribosomal RNA-processing protein 41(gene name synonym)|uniprotkb:Superkiller protein 6(gene name synonym)|uniprotkb:Extracellular mutant protein 20(gene name synonym)|uniprotkb:RRP41(gene name synonym)	psi-mi:ikzf3_human(display_long)|uniprotkb:ZNFN1A3(gene name synonym)|uniprotkb:Ikaros family zinc finger protein 3(gene name synonym)|uniprotkb:IKZF3(gene name)|psi-mi:IKZF3(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11532061|imex:IM-24995-1017	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003427|refseq:NP_011711.3|dip:DIP-2083N|mint:P46948|ensemblfungi:YGR195W(gene)|ensemblfungi:YGR195W_mRNA(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034473"(U1 snRNA 3'-end processing)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0034476"(U5 snRNA 3'-end processing)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071039"(nuclear polyadenylation-dependent CUT catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345|rcsb pdb:2WP8|rcsb pdb:4IFD|rcsb pdb:4OO1|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5G06|rcsb pdb:5JEA|rcsb pdb:5K36|rcsb pdb:5OKZ|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-429958|reactome:R-SCE-450385|reactome:R-SCE-450513|reactome:R-SCE-6791226|sgd:YGR195W(identity)	refseq:NP_001271443.1|refseq:NP_001271444.1|refseq:NP_036613.2|refseq:NP_899051.1|refseq:NP_899052.1|refseq:NP_899053.1|refseq:NP_899054.1|refseq:NP_899055.1|refseq:NP_001271445.1|refseq:NP_001244337.1|refseq:NP_001244338.1|refseq:NP_001244339.1|refseq:NP_001244340.1|refseq:NP_001244341.1|refseq:NP_001244342.1|refseq:NP_001244343.1|ensembl:ENSG00000161405(gene)|ensembl:ENST00000346872(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007498"(mesoderm development)|go:"GO:0009617"(response to bacterium)|go:"GO:0030888"(regulation of B cell proliferation)|go:"GO:0042113"(B cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045577"(regulation of B cell differentiation)|go:"GO:0045619"(regulation of lymphocyte differentiation)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|go:"GO:0046872"(metal ion binding)|dip:DIP-56975N|entrezgene/locuslink:22806(identity)	-	crc64:C80EFFB528A43044	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:I7vEo0EUB1jZO+3v12H0LwVbgmo559292	rogid:2Kp6LefSLfK5VIiE6DmQusFIfMY9606	intact-crc:D415EF6ABE561D4C|rigid:qKDGoE2ZgJtQkWAc5Ljsw98xx9w	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96L14	uniprotkb:P46948	intact:EBI-743488	intact:EBI-1788|uniprotkb:D6VUX7|ensemblfungi:YGR195W	psi-mi:c170l_human(display_long)|uniprotkb:KIAA0470L(gene name synonym)|uniprotkb:CEP170P1(gene name)|psi-mi:CEP170P1(display_short)|uniprotkb:CEP170L(gene name synonym)|uniprotkb:CEP170 pseudogene 1(gene name synonym)	psi-mi:rrp41_yeast(display_long)|uniprotkb:SKI6(gene name)|psi-mi:SKI6(display_short)|uniprotkb:YGR195W(locus name)|uniprotkb:G7587(orf name)|uniprotkb:ECM20(gene name synonym)|uniprotkb:Ribosomal RNA-processing protein 41(gene name synonym)|uniprotkb:Superkiller protein 6(gene name synonym)|uniprotkb:Extracellular mutant protein 20(gene name synonym)|uniprotkb:RRP41(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11532052|imex:IM-24995-1016	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR026644|interpro:IPR029300|go:"GO:0042802"(identical protein binding)|entrezgene/locuslink:645455(identity)	sgd:S000003427|refseq:NP_011711.3|dip:DIP-2083N|mint:P46948|ensemblfungi:YGR195W(gene)|ensemblfungi:YGR195W_mRNA(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034473"(U1 snRNA 3'-end processing)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0034476"(U5 snRNA 3'-end processing)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071039"(nuclear polyadenylation-dependent CUT catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345|rcsb pdb:2WP8|rcsb pdb:4IFD|rcsb pdb:4OO1|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5G06|rcsb pdb:5JEA|rcsb pdb:5K36|rcsb pdb:5OKZ|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-429958|reactome:R-SCE-450385|reactome:R-SCE-450513|reactome:R-SCE-6791226|sgd:YGR195W(identity)	-	-	crc64:C80EFFB528A43044	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Z/Rium0Kwj3ZUHa4WE5PPksPXdg9606	rogid:I7vEo0EUB1jZO+3v12H0LwVbgmo559292	intact-crc:339ED1FDFAB84D7A|rigid:lfDGJ3ZVkgNWvR78oVXv8QekVDA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96BA8	uniprotkb:P46956	intact:EBI-6942903|ensembl:ENSP00000481956|intact:MINT-268046|intact:MINT-8162577|uniprotkb:Q8N2D5|uniprotkb:Q96CP0	intact:EBI-13337|uniprotkb:E9P8T7|ensemblfungi:YJL117W|uniprotkb:D6VW67	psi-mi:cr3l1_human(display_long)|uniprotkb:CREB3L1(gene name)|psi-mi:CREB3L1(display_short)|uniprotkb:OASIS(gene name synonym)|uniprotkb:PSEC0238(orf name)|uniprotkb:Old astrocyte specifically-induced substance(gene name synonym)	psi-mi:pho86_yeast(display_long)|uniprotkb:PHO86(gene name)|psi-mi:PHO86(display_short)|uniprotkb:J0744(orf name)|uniprotkb:YJL117W(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11532088|imex:IM-24995-1020	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157613(gene)|ensembl:ENST00000621158(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0070278"(extracellular matrix constituent secretion)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029805|mint:Q96BA8|reactome:R-HSA-8874211|refseq:NP_443086.1|entrezgene/locuslink:90993(identity)	refseq:NP_012418.1|sgd:S000003653|interpro:IPR024297|ensemblfungi:YJL117W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006457"(protein folding)|go:"GO:0006817"(phosphate ion transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0010966"(regulation of phosphate transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0051082"(unfolded protein binding)|ensemblfungi:YJL117W(gene)|mint:P46956|dip:DIP-2769N|sgd:YJL117W(identity)	-	comment:mint|function:"Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE"	crc64:1CB19C9184BF1C48	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:sMWUFmBeBBCO+T0Y2CuB/un1lBg9606	rogid:JITWReptfMoij1Uy6y1e3Oa6dAs559292	intact-crc:CD644E5D2670DDB2|rigid:zNFUhUB559mW5v40Np8eyOmhspM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8TAP6	uniprotkb:P46948	intact:EBI-742887|ensembl:ENSP00000262127|uniprotkb:Q658N5|uniprotkb:Q9H9U7|uniprotkb:B0YJB2|uniprotkb:B4DXG5|uniprotkb:B4DZW1	intact:EBI-1788|uniprotkb:D6VUX7|ensemblfungi:YGR195W	psi-mi:cep76_human(display_long)|uniprotkb:CEP76(gene name)|psi-mi:CEP76(display_short)|uniprotkb:C18orf9(gene name synonym)	psi-mi:rrp41_yeast(display_long)|uniprotkb:SKI6(gene name)|psi-mi:SKI6(display_short)|uniprotkb:YGR195W(locus name)|uniprotkb:G7587(orf name)|uniprotkb:ECM20(gene name synonym)|uniprotkb:Ribosomal RNA-processing protein 41(gene name synonym)|uniprotkb:Superkiller protein 6(gene name synonym)|uniprotkb:Extracellular mutant protein 20(gene name synonym)|uniprotkb:RRP41(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11532043|imex:IM-24995-1015	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_079175.2|ensembl:ENSG00000101624(gene)|ensembl:ENST00000262127(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0046599"(regulation of centriole replication)|interpro:IPR028926|interpro:IPR038765|mint:Q8TAP6|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_001258918.1|entrezgene/locuslink:79959(identity)	sgd:S000003427|refseq:NP_011711.3|dip:DIP-2083N|mint:P46948|ensemblfungi:YGR195W(gene)|ensemblfungi:YGR195W_mRNA(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034473"(U1 snRNA 3'-end processing)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0034476"(U5 snRNA 3'-end processing)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071039"(nuclear polyadenylation-dependent CUT catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345|rcsb pdb:2WP8|rcsb pdb:4IFD|rcsb pdb:4OO1|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5G06|rcsb pdb:5JEA|rcsb pdb:5K36|rcsb pdb:5OKZ|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-429958|reactome:R-SCE-450385|reactome:R-SCE-450513|reactome:R-SCE-6791226|sgd:YGR195W(identity)	-	-	crc64:C80EFFB528A43044	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:fWzb8oIU35oVWomyDrf8u5sbxUk9606	rogid:I7vEo0EUB1jZO+3v12H0LwVbgmo559292	intact-crc:81FB63CBFA1E976E|rigid:5TWeomSSqBF09jLn+neEbi3/SeA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P46965	uniprotkb:Q8N6L0	intact:EBI-17823|uniprotkb:D6VWI6|ensemblfungi:YJR010C-A	intact:EBI-749265|uniprotkb:Q96MC3|ensembl:ENSP00000404220	psi-mi:spc1_yeast(display_long)|uniprotkb:SPC1(gene name)|psi-mi:SPC1(display_short)|uniprotkb:YJR010C-A(locus name)|uniprotkb:YJR010BW(orf name)|uniprotkb:Microsomal signal peptidase subunit 1(gene name synonym)	psi-mi:kash5_human(display_long)|uniprotkb:KASH5(gene name)|psi-mi:KASH5(display_short)|uniprotkb:CCDC155(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 155(gene name synonym)|uniprotkb:KASH domain-containing protein 5(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11532098|imex:IM-24995-1021	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012544.1|sgd:S000003770|ensemblfungi:YJR010C-A(gene)|ensemblfungi:YJR010C-A_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005787"(signal peptidase complex)|go:"GO:0006465"(signal peptide processing)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0045047"(protein targeting to ER)|interpro:IPR009542(Microsomal signal peptidase 12 kDa subunit)|interpro:IPR037713|mint:P46965|dip:DIP-2770N|sgd:YJR010C-A(identity)	refseq:NP_653289.3|ensembl:ENSG00000161609(gene)|ensembl:ENST00000447857(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034397"(telomere localization)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051225"(spindle assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0090172"(microtubule cytoskeleton organization involved in homologous chromosome segregation)|go:"GO:0090220"(chromosome localization to nuclear envelope involved in homologous chromosome segregation)|go:"GO:0090619"(meiotic spindle pole)|interpro:IPR011992(EF-Hand type)|interpro:IPR028168|interpro:IPR028170|interpro:IPR039508|mint:Q8N6L0|rcsb pdb:6R2I|rcsb pdb:6WMF|entrezgene/locuslink:147872(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:kchUi3mkadvzweVkrWO3QkbbHew559292	rogid:Wl9L7AcvDHCZuKjYLn8QgGIbZTc9606	intact-crc:BE7C98DDB74C5CA3|rigid:q6X7Z1tL2sUDclMaelgwNgDtn90	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P63279	uniprotkb:P46985	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	intact:EBI-11052|uniprotkb:E9P8Z0|ensemblfungi:YJL183W|uniprotkb:D6VW07	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:mnn11_yeast(display_long)|uniprotkb:MNN11(gene name)|psi-mi:MNN11(display_short)|uniprotkb:YJL183W(locus name)|uniprotkb:J0425(orf name)|uniprotkb:Mannan polymerase II complex MNN11 subunit(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11532107|imex:IM-24995-1022	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N|entrezgene/locuslink:7329(identity)	ensemblfungi:YJL183W(gene)|ensemblfungi:YJL183W_mRNA(transcript)|go:"GO:0000009"(alpha-1,6-mannosyltransferase activity)|go:"GO:0000032"(cell wall mannoprotein biosynthetic process)|go:"GO:0000136"(mannan polymerase complex)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006487"(protein N-linked glycosylation)|interpro:IPR008630(Galactosyl transferase)|interpro:IPR029044|go:"GO:0000139"(Golgi membrane)|refseq:NP_012352.2|sgd:S000003719|dip:DIP-914N|sgd:YJL183W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	rogid:JInEivytHOK2ZvKHg1LamaaIR70559292	intact-crc:7C4908641A5EC364|rigid:BC7/cijqzTCyCeVyp5im1PNdh/w	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8WV44	uniprotkb:P47009	intact:EBI-725997|uniprotkb:Q5BKT0|uniprotkb:Q7L484|uniprotkb:Q96Q10|intact:EBI-1551110|uniprotkb:Q9BSL8|uniprotkb:B3KNJ6|uniprotkb:D3DWR9|ensembl:ENSP00000320869	intact:EBI-3680883|uniprotkb:D6VW41|ensemblfungi:YJL144W	psi-mi:tri41_human(display_long)|uniprotkb:TRIM41(gene name)|psi-mi:TRIM41(display_short)|uniprotkb:RINCK(gene name synonym)|uniprotkb:Tripartite motif-containing protein 41(gene name synonym)|uniprotkb:RING finger-interacting protein with C kinase(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM41(gene name synonym)	psi-mi:yjo4_yeast(display_long)|uniprotkb:J0646(orf name)|uniprotkb:YJL144W(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11532116|imex:IM-24995-1023	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_291027.3|refseq:NP_963921.1|ensembl:ENSG00000146063(gene)|ensembl:ENST00000315073(transcript)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0042802"(identical protein binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071225"(cellular response to muramyl dipeptide)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR042828|interpro:IPR043136|mint:Q8WV44|rcsb pdb:2EGM|reactome:R-HSA-983168|entrezgene/locuslink:90933(identity)	mint:P47009|sgd:S000003680|refseq:NP_012391.1|ensemblfungi:YJL144W(gene)|ensemblfungi:YJL144W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0042631"(cellular response to water deprivation)|go:"GO:0055106"(ubiquitin-protein transferase regulator activity)|go:"GO:0120174"(stress-induced homeostatically regulated protein degradation pathway)|sgd:YJL144W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:BVqf0OHXPGsYe8F66mHzvD4XQ549606	rogid:7kshIHHxzHSMcpP1vGF+sbEHkfA559292	intact-crc:1E18D67F13ED9374|rigid:eN9UKvDnLfl7ng9xKtR6h2Aal4U	false	sufficient binding region:86-630	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P47041	uniprotkb:P08727	intact:EBI-25889|uniprotkb:D6VWC4|ensemblfungi:YJL058C	intact:EBI-742756|uniprotkb:Q5XG83|uniprotkb:Q6NW33|uniprotkb:Q7L5M9|uniprotkb:Q96A53|uniprotkb:Q96FV1|uniprotkb:Q9BYF9|uniprotkb:Q9P1Y4|uniprotkb:B2R874|ensembl:ENSP00000355124	psi-mi:bit61_yeast(display_long)|uniprotkb:YJL058C(locus name)|uniprotkb:J1141(orf name)|uniprotkb:61 kDa binding partner of TOR2 protein(gene name synonym)|uniprotkb:BIT61(gene name)|psi-mi:BIT61(display_short)	psi-mi:k1c19_human(display_long)|uniprotkb:Cytokeratin-19(gene name synonym)|uniprotkb:Keratin-19(gene name synonym)|uniprotkb:KRT19(gene name)|psi-mi:KRT19(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11532176|imex:IM-24995-1029	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012477.1|sgd:S000003594|dip:DIP-1444N|reactome:R-SCE-1257604|reactome:R-SCE-389357|reactome:R-SCE-5218920|ensemblfungi:YJL058C(gene)|ensemblfungi:YJL058C_mRNA(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005737"(cytoplasm)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0031932"(TORC2 complex)|go:"GO:0038203"(TORC2 signaling)|go:"GO:0071944"(cell periphery)|interpro:IPR013745(HbrB-like)|reactome:R-SCE-6804757|sgd:YJL058C(identity)	refseq:NP_002267.2|ensembl:ENSG00000171345(gene)|ensembl:ENST00000361566(transcript)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0030018"(Z disc)|go:"GO:0042383"(sarcolemma)|go:"GO:0043034"(costamere)|go:"GO:0043627"(response to estrogen)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0060706"(cell differentiation involved in embryonic placenta development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071944"(cell periphery)|go:"GO:1990357"(terminal web)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR039008|mint:P08727|reactome:R-HSA-6805567|reactome:R-HSA-6809371|dip:DIP-35655N|entrezgene/locuslink:3880(identity)	-	crc64:99F0F96840311F4B	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:H+zcKwbWL90wsmvD9TfWYmEbRwM559292	rogid:fqsG2nghpcmTtI39LiYVLNYuFIA9606	intact-crc:195A326A060CBF82|rigid:aYJO7KBTuT1h4d2KpovFGq0CFeI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q08379	uniprotkb:P47041	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	intact:EBI-25889|uniprotkb:D6VWC4|ensemblfungi:YJL058C	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:bit61_yeast(display_long)|uniprotkb:YJL058C(locus name)|uniprotkb:J1141(orf name)|uniprotkb:61 kDa binding partner of TOR2 protein(gene name synonym)|uniprotkb:BIT61(gene name)|psi-mi:BIT61(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11532154|imex:IM-24995-1027	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N|entrezgene/locuslink:2801(identity)	refseq:NP_012477.1|sgd:S000003594|dip:DIP-1444N|reactome:R-SCE-1257604|reactome:R-SCE-389357|reactome:R-SCE-5218920|ensemblfungi:YJL058C(gene)|ensemblfungi:YJL058C_mRNA(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005737"(cytoplasm)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0031932"(TORC2 complex)|go:"GO:0038203"(TORC2 signaling)|go:"GO:0071944"(cell periphery)|interpro:IPR013745(HbrB-like)|reactome:R-SCE-6804757|sgd:YJL058C(identity)	-	-	crc64:99F0F96840311F4B	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2017/05/26	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	rogid:H+zcKwbWL90wsmvD9TfWYmEbRwM559292	intact-crc:AC9B77197FCB18C6|rigid:yqQ5oEjpGHrzS/87teheWUEjnyw	false	sufficient binding region:383-1002	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
intact:EBI-11524292	uniprotkb:P47041	-	intact:EBI-25889|uniprotkb:D6VWC4|ensemblfungi:YJL058C	psi-mi:trip6(display_short)|psi-mi:EBI-11524292(display_long)	psi-mi:bit61_yeast(display_long)|uniprotkb:YJL058C(locus name)|uniprotkb:J1141(orf name)|uniprotkb:61 kDa binding partner of TOR2 protein(gene name synonym)|uniprotkb:BIT61(gene name)|psi-mi:BIT61(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11532145|imex:IM-24995-1026	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	entrezgene/locuslink:7205(identity)	refseq:NP_012477.1|sgd:S000003594|dip:DIP-1444N|reactome:R-SCE-1257604|reactome:R-SCE-389357|reactome:R-SCE-5218920|ensemblfungi:YJL058C(gene)|ensemblfungi:YJL058C_mRNA(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005737"(cytoplasm)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0031932"(TORC2 complex)|go:"GO:0038203"(TORC2 signaling)|go:"GO:0071944"(cell periphery)|interpro:IPR013745(HbrB-like)|reactome:R-SCE-6804757|sgd:YJL058C(identity)	-	no-uniprot-update:	crc64:99F0F96840311F4B	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:S6W5lkNauGhNejln9bTVoqZjNL49606	rogid:H+zcKwbWL90wsmvD9TfWYmEbRwM559292	intact-crc:9604C6DCA822CEFF|rigid:74ZznwJbqsjScwdu24D4Z64KWeg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P47041	uniprotkb:Q8N5R6	intact:EBI-25889|uniprotkb:D6VWC4|ensemblfungi:YJL058C	intact:EBI-740841|intact:EBI-953781|uniprotkb:B3KQ49|uniprotkb:A8K3U4|uniprotkb:A8MPQ6|uniprotkb:A8MV61|uniprotkb:A8MVU9|uniprotkb:Q9H5Q6|uniprotkb:Q8TAX6|intact:EBI-2320546|intact:EBI-11522976	psi-mi:bit61_yeast(display_long)|uniprotkb:YJL058C(locus name)|uniprotkb:J1141(orf name)|uniprotkb:61 kDa binding partner of TOR2 protein(gene name synonym)|uniprotkb:BIT61(gene name)|psi-mi:BIT61(display_short)	psi-mi:ccd33_human(display_long)|uniprotkb:CCDC33(gene name)|psi-mi:CCDC33(display_short)|uniprotkb:Cancer/testis antigen 61(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11532136|imex:IM-24995-1025	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012477.1|sgd:S000003594|dip:DIP-1444N|reactome:R-SCE-1257604|reactome:R-SCE-389357|reactome:R-SCE-5218920|ensemblfungi:YJL058C(gene)|ensemblfungi:YJL058C_mRNA(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005737"(cytoplasm)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0031932"(TORC2 complex)|go:"GO:0038203"(TORC2 signaling)|go:"GO:0071944"(cell periphery)|interpro:IPR013745(HbrB-like)|reactome:R-SCE-6804757|sgd:YJL058C(identity)	refseq:NP_079331.3|interpro:IPR000008(C2 calcium-dependent membrane targeting)|go:"GO:0005777"(peroxisome)|refseq:NP_001274110.1|refseq:NP_877592.2|mint:Q8N5R6|interpro:IPR035892|interpro:IPR039889|entrezgene/locuslink:80125(identity)	-	crc64:99F0F96840311F4B	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2021/11/30	rogid:H+zcKwbWL90wsmvD9TfWYmEbRwM559292	rogid:eEIn7pQyfdHWx8TeLJpYy0i/gww9606	intact-crc:A64582539FA044E2|rigid:LPWQIXNF9ahpGT/y0LCTww/kmqU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P47013	uniprotkb:Q8N6L0	intact:EBI-26081|uniprotkb:D6VW50|ensemblfungi:YJL134W	intact:EBI-749265|uniprotkb:Q96MC3|ensembl:ENSP00000404220	psi-mi:ds1p1_yeast(display_long)|uniprotkb:YJL134W(locus name)|uniprotkb:J0671(orf name)|uniprotkb:LCB3(gene name)|psi-mi:LCB3(display_short)|uniprotkb:LBP1(gene name synonym)|uniprotkb:YSR2(gene name synonym)|uniprotkb:Long-chain base protein 3(gene name synonym)|uniprotkb:Sphingolipid resistance protein 2(gene name synonym)	psi-mi:kash5_human(display_long)|uniprotkb:KASH5(gene name)|psi-mi:KASH5(display_short)|uniprotkb:CCDC155(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 155(gene name synonym)|uniprotkb:KASH domain-containing protein 5(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11532127|imex:IM-24995-1024	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012401.1|sgd:S000003670|reactome:R-SCE-1660661|dip:DIP-5685N|ensemblfungi:YJL134W(gene)|ensemblfungi:YJL134W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0042392"(sphingosine-1-phosphate phosphatase activity)|go:"GO:0046839"(phospholipid dephosphorylation)|go:"GO:0070780"(dihydrosphingosine-1-phosphate phosphatase activity)|interpro:IPR000326(Phosphatidic acid phosphatase type 2/haloperoxidase)|interpro:IPR036938|sgd:YJL134W(identity)	refseq:NP_653289.3|ensembl:ENSG00000161609(gene)|ensembl:ENST00000447857(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034397"(telomere localization)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051225"(spindle assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0090172"(microtubule cytoskeleton organization involved in homologous chromosome segregation)|go:"GO:0090220"(chromosome localization to nuclear envelope involved in homologous chromosome segregation)|go:"GO:0090619"(meiotic spindle pole)|interpro:IPR011992(EF-Hand type)|interpro:IPR028168|interpro:IPR028170|interpro:IPR039508|mint:Q8N6L0|rcsb pdb:6R2I|rcsb pdb:6WMF|entrezgene/locuslink:147872(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:PY4waY+3MkYSvto7aiARAO5UHzI559292	rogid:Wl9L7AcvDHCZuKjYLn8QgGIbZTc9606	intact-crc:CEC589A296776634|rigid:y76M63Y2OBtRHIjH4BLDQsH9Kqc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:A0A0R4J2E4	uniprotkb:P47041	intact:EBI-11525602|ensembl:ENSP00000324292	intact:EBI-25889|uniprotkb:D6VWC4|ensemblfungi:YJL058C	psi-mi:a0a0r4j2e4_human(display_long)|uniprotkb:FBF1(gene name)|psi-mi:FBF1(display_short)	psi-mi:bit61_yeast(display_long)|uniprotkb:YJL058C(locus name)|uniprotkb:J1141(orf name)|uniprotkb:61 kDa binding partner of TOR2 protein(gene name synonym)|uniprotkb:BIT61(gene name)|psi-mi:BIT61(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11532165|imex:IM-24995-1028	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000188878(gene)|ensembl:ENST00000319129(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0060271"(cilium assembly)|go:"GO:0090162"(establishment of epithelial cell polarity)|go:"GO:0097539"(ciliary transition fiber)|interpro:IPR033561|entrezgene/locuslink:85302(identity)	refseq:NP_012477.1|sgd:S000003594|dip:DIP-1444N|reactome:R-SCE-1257604|reactome:R-SCE-389357|reactome:R-SCE-5218920|ensemblfungi:YJL058C(gene)|ensemblfungi:YJL058C_mRNA(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005737"(cytoplasm)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0031932"(TORC2 complex)|go:"GO:0038203"(TORC2 signaling)|go:"GO:0071944"(cell periphery)|interpro:IPR013745(HbrB-like)|reactome:R-SCE-6804757|sgd:YJL058C(identity)	-	-	crc64:99F0F96840311F4B	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/03/16	rogid:N4h8foiP1+HSYZRE7i66zhtqKlQ9606	rogid:H+zcKwbWL90wsmvD9TfWYmEbRwM559292	intact-crc:7B7889CF0419FD91|rigid:IpsLsdQqXZdgJahitU1+lffJJ5s	false	sufficient binding region:649-1092	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8IYA8	uniprotkb:P47041	intact:EBI-8638439|intact:EBI-28969497|ensembl:ENSP00000296449|ensembl:ENSP00000391788|ensembl:ENSP00000407837|uniprotkb:C9JJL0|uniprotkb:Q96LP7|intact:MINT-8162095|uniprotkb:Q05DG9	intact:EBI-25889|uniprotkb:D6VWC4|ensemblfungi:YJL058C	psi-mi:iho1_human(display_long)|uniprotkb:IHO1(gene name)|psi-mi:IHO1(display_short)|uniprotkb:CCDC36(gene name synonym)|uniprotkb:Cancer/testis antigen 74(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 36(gene name synonym)	psi-mi:bit61_yeast(display_long)|uniprotkb:YJL058C(locus name)|uniprotkb:J1141(orf name)|uniprotkb:61 kDa binding partner of TOR2 protein(gene name synonym)|uniprotkb:BIT61(gene name)|psi-mi:BIT61(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11532241|imex:IM-24995-1036	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000296449|ensembl:ENST00000366429|ensembl:ENSP00000403700|ensembl:ENSP00000391788|ensembl:ENSP00000407837|ensembl:ENSG00000173421(gene)|ensembl:ENST00000296449(transcript)|ensembl:ENST00000438782(transcript)|ensembl:ENST00000452691(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0006310"(DNA recombination)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0042138"(meiotic DNA double-strand break formation)|go:"GO:0048477"(oogenesis)|go:"GO:0060629"(regulation of homologous chromosome segregation)|interpro:IPR031529|mint:Q8IYA8|refseq:XP_011531974.1|refseq:XP_011531975.1|refseq:NP_001128669.1|refseq:NP_835467.2|refseq:XP_006713187.1|entrezgene/locuslink:339834(identity)	refseq:NP_012477.1|sgd:S000003594|dip:DIP-1444N|reactome:R-SCE-1257604|reactome:R-SCE-389357|reactome:R-SCE-5218920|ensemblfungi:YJL058C(gene)|ensemblfungi:YJL058C_mRNA(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005737"(cytoplasm)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0031932"(TORC2 complex)|go:"GO:0038203"(TORC2 signaling)|go:"GO:0071944"(cell periphery)|interpro:IPR013745(HbrB-like)|reactome:R-SCE-6804757|sgd:YJL058C(identity)	-	comment:mint	crc64:99F0F96840311F4B	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:+TNQLExkhmC1NWqsE240Cx7zFVU9606	rogid:H+zcKwbWL90wsmvD9TfWYmEbRwM559292	intact-crc:F6A43ECA9CEE25C7|rigid:7jlmiMLt3QumiVKx94sv7aao7xc	false	sufficient binding region:11-594	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P47041	uniprotkb:Q5JST6	intact:EBI-25889|uniprotkb:D6VWC4|ensemblfungi:YJL058C	intact:EBI-2349927|uniprotkb:Q9H653|uniprotkb:Q5JST8|uniprotkb:Q68DK4|uniprotkb:Q8NEI0|intact:EBI-28971886|ensembl:ENSP00000404232	psi-mi:bit61_yeast(display_long)|uniprotkb:YJL058C(locus name)|uniprotkb:J1141(orf name)|uniprotkb:61 kDa binding partner of TOR2 protein(gene name synonym)|uniprotkb:BIT61(gene name)|psi-mi:BIT61(display_short)	psi-mi:efhc2_human(display_long)|uniprotkb:EFHC2(gene name)|psi-mi:EFHC2(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11532232|imex:IM-24995-1035	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012477.1|sgd:S000003594|dip:DIP-1444N|reactome:R-SCE-1257604|reactome:R-SCE-389357|reactome:R-SCE-5218920|ensemblfungi:YJL058C(gene)|ensemblfungi:YJL058C_mRNA(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005737"(cytoplasm)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0031932"(TORC2 complex)|go:"GO:0038203"(TORC2 signaling)|go:"GO:0071944"(cell periphery)|interpro:IPR013745(HbrB-like)|reactome:R-SCE-6804757|sgd:YJL058C(identity)	ensembl:ENSP00000404232|refseq:NP_079460.2|ensembl:ENSG00000183690(gene)|ensembl:ENST00000420999(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005930"(axoneme)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0060285"(cilium-dependent cell motility)|go:"GO:0072686"(mitotic spindle)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR006602(Region of unknown function DM10)|interpro:IPR011992(EF-Hand type)|interpro:IPR040193|rcsb pdb:2Z13|rcsb pdb:2Z14|entrezgene/locuslink:80258(identity)	-	crc64:99F0F96840311F4B	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:H+zcKwbWL90wsmvD9TfWYmEbRwM559292	rogid:O1XriQSkLcYkk7H7AlanQ1FKIBY9606	intact-crc:86333DD546988091|rigid:04DO0Pw4mEQB80QbSnV9DtvHa8A	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P47041	uniprotkb:Q15654	intact:EBI-25889|uniprotkb:D6VWC4|ensemblfungi:YJL058C	intact:EBI-742327|uniprotkb:O15170|uniprotkb:O15275|uniprotkb:Q9BTB2|uniprotkb:Q9BUE5|uniprotkb:Q9BXP3|uniprotkb:Q9UNT4|uniprotkb:A4D2E7|ensembl:ENSP00000200457|uniprotkb:F2ZC07|uniprotkb:F2ZC08	psi-mi:bit61_yeast(display_long)|uniprotkb:YJL058C(locus name)|uniprotkb:J1141(orf name)|uniprotkb:61 kDa binding partner of TOR2 protein(gene name synonym)|uniprotkb:BIT61(gene name)|psi-mi:BIT61(display_short)	psi-mi:trip6_human(display_long)|uniprotkb:TRIP6(gene name)|psi-mi:TRIP6(display_short)|uniprotkb:OIP1(gene name synonym)|uniprotkb:Opa-interacting protein 1(gene name synonym)|uniprotkb:Zyxin-related protein 1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11532213|imex:IM-24995-1033	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012477.1|sgd:S000003594|dip:DIP-1444N|reactome:R-SCE-1257604|reactome:R-SCE-389357|reactome:R-SCE-5218920|ensemblfungi:YJL058C(gene)|ensemblfungi:YJL058C_mRNA(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005737"(cytoplasm)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0031932"(TORC2 complex)|go:"GO:0038203"(TORC2 signaling)|go:"GO:0071944"(cell periphery)|interpro:IPR013745(HbrB-like)|reactome:R-SCE-6804757|sgd:YJL058C(identity)	refseq:NP_003293.2|ensembl:ENSP00000200457|ensembl:ENST00000417475|ensembl:ENSP00000413817|ensembl:ENST00000437505|ensembl:ENSP00000410736|ensembl:ENST00000619988|ensembl:ENSP00000479865|ensembl:ENSG00000087077(gene)|ensembl:ENST00000200457(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003723"(RNA binding)|go:"GO:0005149"(interleukin-1 receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0019900"(kinase binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0043009"(chordate embryonic development)|go:"GO:0046872"(metal ion binding)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|interpro:IPR001781(Zinc finger, LIM-type)|mint:Q15654|rcsb pdb:1X61|rcsb pdb:2DLO|dip:DIP-34466N|entrezgene/locuslink:7205(identity)	-	crc64:99F0F96840311F4B	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:H+zcKwbWL90wsmvD9TfWYmEbRwM559292	rogid:9Okf3b6sMMwX5awAx991GN9iSsQ9606	intact-crc:52F53C2EFD1940C5|rigid:TfpCjtS5+M2jhCdi2e0hjGITtNk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P19012	uniprotkb:P47041	intact:EBI-739566|uniprotkb:Q53XV8|uniprotkb:Q9BUG4|uniprotkb:B3KQY1|uniprotkb:B3KRA2|uniprotkb:E0CX14|ensembl:ENSP00000254043|ensembl:ENSP00000377546	intact:EBI-25889|uniprotkb:D6VWC4|ensemblfungi:YJL058C	psi-mi:k1c15_human(display_long)|uniprotkb:KRT15(gene name)|psi-mi:KRT15(display_short)|uniprotkb:KRTB(gene name synonym)|uniprotkb:Cytokeratin-15(gene name synonym)|uniprotkb:Keratin-15(gene name synonym)	psi-mi:bit61_yeast(display_long)|uniprotkb:YJL058C(locus name)|uniprotkb:J1141(orf name)|uniprotkb:61 kDa binding partner of TOR2 protein(gene name synonym)|uniprotkb:BIT61(gene name)|psi-mi:BIT61(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11532204|imex:IM-24995-1032	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002266.2|ensembl:ENSG00000171346(gene)|ensembl:ENST00000254043(transcript)|ensembl:ENST00000393976(transcript)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0008544"(epidermis development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097110"(scaffold protein binding)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR039008|mint:P19012|reactome:R-HSA-6805567|reactome:R-HSA-6809371|entrezgene/locuslink:3866(identity)	refseq:NP_012477.1|sgd:S000003594|dip:DIP-1444N|reactome:R-SCE-1257604|reactome:R-SCE-389357|reactome:R-SCE-5218920|ensemblfungi:YJL058C(gene)|ensemblfungi:YJL058C_mRNA(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005737"(cytoplasm)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0031932"(TORC2 complex)|go:"GO:0038203"(TORC2 signaling)|go:"GO:0071944"(cell periphery)|interpro:IPR013745(HbrB-like)|reactome:R-SCE-6804757|sgd:YJL058C(identity)	-	-	crc64:99F0F96840311F4B	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:WrZQBYQvrWcfrR5ojWXrXp6spPE9606	rogid:H+zcKwbWL90wsmvD9TfWYmEbRwM559292	intact-crc:7ED4EED142677ABC|rigid:6HX1d/7oa0CN5IOpc0gDYAlr24c	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P14373	uniprotkb:P47041	intact:EBI-719493|uniprotkb:A2BE15|uniprotkb:Q5RJA8|uniprotkb:Q5ST26|uniprotkb:Q6LA73|uniprotkb:Q6NXR9|uniprotkb:Q9BZY6|uniprotkb:Q9UJL3|ensembl:ENSP00000383555|ensembl:ENSP00000392787|ensembl:ENSP00000405229|ensembl:ENSP00000414793|ensembl:ENSP00000366404	intact:EBI-25889|uniprotkb:D6VWC4|ensemblfungi:YJL058C	psi-mi:tri27_human(display_long)|uniprotkb:TRIM27(gene name)|psi-mi:TRIM27(display_short)|uniprotkb:RNF76(gene name synonym)|uniprotkb:RFP(gene name synonym)|uniprotkb:Ret finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 27(gene name synonym)|uniprotkb:RING finger protein 76(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM27(gene name synonym)	psi-mi:bit61_yeast(display_long)|uniprotkb:YJL058C(locus name)|uniprotkb:J1141(orf name)|uniprotkb:61 kDa binding partner of TOR2 protein(gene name synonym)|uniprotkb:BIT61(gene name)|psi-mi:BIT61(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11532195|imex:IM-24995-1031	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006501.1|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0090281"(negative regulation of calcium ion import)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR020457|interpro:IPR035791|interpro:IPR043136|mint:P14373|reactome:R-HSA-3232142|reactome:R-HSA-9635465|reactome:R-HSA-8948751|ensembl:ENSG00000204713(gene)|ensembl:ENSG00000215641(gene)|ensembl:ENSG00000229006(gene)|ensembl:ENSG00000234495(gene)|ensembl:ENSG00000237071(gene)|ensembl:ENST00000377199(transcript)|ensembl:ENST00000400720(transcript)|ensembl:ENST00000431123(transcript)|ensembl:ENST00000435528(transcript)|ensembl:ENST00000437160(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001650"(fibrillar center)|go:"GO:0002820"(negative regulation of adaptive immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|entrezgene/locuslink:5987(identity)	refseq:NP_012477.1|sgd:S000003594|dip:DIP-1444N|reactome:R-SCE-1257604|reactome:R-SCE-389357|reactome:R-SCE-5218920|ensemblfungi:YJL058C(gene)|ensemblfungi:YJL058C_mRNA(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005737"(cytoplasm)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0031932"(TORC2 complex)|go:"GO:0038203"(TORC2 signaling)|go:"GO:0071944"(cell periphery)|interpro:IPR013745(HbrB-like)|reactome:R-SCE-6804757|sgd:YJL058C(identity)	-	-	crc64:99F0F96840311F4B	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:dsfH5OUghD8KSaTz1SFw9OYVTK49606	rogid:H+zcKwbWL90wsmvD9TfWYmEbRwM559292	intact-crc:235E6A47456FDB70|rigid:pFtOvJZe1d+/3DINI56Dp1R+MIE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P14136	uniprotkb:P47041	intact:EBI-744302|uniprotkb:Q53H98|uniprotkb:Q5D055|uniprotkb:Q6ZQS3|uniprotkb:Q7Z5J6|uniprotkb:Q7Z5J7|uniprotkb:Q96KS4|uniprotkb:Q96P18|uniprotkb:Q9UFD0|uniprotkb:B2RD44|uniprotkb:D3DX59|intact:EBI-3909365|uniprotkb:E9PAX3|ensembl:ENSP00000466598|uniprotkb:A7REI1	intact:EBI-25889|uniprotkb:D6VWC4|ensemblfungi:YJL058C	psi-mi:gfap_human(display_long)|uniprotkb:GFAP(gene name)|psi-mi:GFAP(display_short)	psi-mi:bit61_yeast(display_long)|uniprotkb:YJL058C(locus name)|uniprotkb:J1141(orf name)|uniprotkb:61 kDa binding partner of TOR2 protein(gene name synonym)|uniprotkb:BIT61(gene name)|psi-mi:BIT61(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11532186|imex:IM-24995-1030	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001124491.1|refseq:NP_001229305.1|refseq:NP_002046.1|ensembl:ENSG00000131095(gene)|ensembl:ENST00000588735(transcript)|go:"GO:0005178"(integrin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0009611"(response to wounding)|go:"GO:0010467"(gene expression)|go:"GO:0010625"(positive regulation of Schwann cell proliferation)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0014002"(astrocyte development)|go:"GO:0019900"(kinase binding)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0031102"(neuron projection regeneration)|go:"GO:0042802"(identical protein binding)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0044297"(cell body)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0051580"(regulation of neurotransmitter uptake)|go:"GO:0060020"(Bergmann glial cell differentiation)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0070779"(D-aspartate import across plasma membrane)|go:"GO:0097450"(astrocyte end-foot)|go:"GO:0098574"(cytoplasmic side of lysosomal membrane)|go:"GO:1904714"(regulation of chaperone-mediated autophagy)|interpro:IPR006821(Intermediate filament, DNA-binding region)|interpro:IPR018039|interpro:IPR027701|interpro:IPR039008|mint:P14136|rcsb pdb:6A9P|reactome:R-HSA-1251985|reactome:R-HSA-9613829|entrezgene/locuslink:2670(identity)	refseq:NP_012477.1|sgd:S000003594|dip:DIP-1444N|reactome:R-SCE-1257604|reactome:R-SCE-389357|reactome:R-SCE-5218920|ensemblfungi:YJL058C(gene)|ensemblfungi:YJL058C_mRNA(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005737"(cytoplasm)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0031932"(TORC2 complex)|go:"GO:0038203"(TORC2 signaling)|go:"GO:0071944"(cell periphery)|interpro:IPR013745(HbrB-like)|reactome:R-SCE-6804757|sgd:YJL058C(identity)	-	-	crc64:99F0F96840311F4B	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Pz4JW0WjMjBYILTDSX9jUmMqWhg9606	rogid:H+zcKwbWL90wsmvD9TfWYmEbRwM559292	intact-crc:EDCE388565E50C8C|rigid:Rk41K0v8fDB/mhKbElLL99T1QDQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P47041	uniprotkb:Q5JR59-3	intact:EBI-25889|uniprotkb:D6VWC4|ensemblfungi:YJL058C	intact:EBI-11522433|ensembl:ENSP00000370186	psi-mi:bit61_yeast(display_long)|uniprotkb:YJL058C(locus name)|uniprotkb:J1141(orf name)|uniprotkb:61 kDa binding partner of TOR2 protein(gene name synonym)|uniprotkb:BIT61(gene name)|psi-mi:BIT61(display_short)	psi-mi:q5jr59-3(display_long)|uniprotkb:MTUS2(gene name)|psi-mi:MTUS2(display_short)|uniprotkb:CAZIP(gene name synonym)|uniprotkb:Cardiac zipper protein(gene name synonym)|uniprotkb:KIAA0774(gene name synonym)|uniprotkb:Microtubule plus-end tracking protein TIP150(gene name synonym)|uniprotkb:TIP150(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11532223|imex:IM-24995-1034	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012477.1|sgd:S000003594|dip:DIP-1444N|reactome:R-SCE-1257604|reactome:R-SCE-389357|reactome:R-SCE-5218920|ensemblfungi:YJL058C(gene)|ensemblfungi:YJL058C_mRNA(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005737"(cytoplasm)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0031932"(TORC2 complex)|go:"GO:0038203"(TORC2 signaling)|go:"GO:0071944"(cell periphery)|interpro:IPR013745(HbrB-like)|reactome:R-SCE-6804757|sgd:YJL058C(identity)	ensembl:ENSG00000132938(gene)|ensembl:ENST00000380808(transcript)|intact:EBI-742948(isoform-parent)|uniprotkb:Q5JR59-3(isoform-parent)|entrezgene/locuslink:23281(identity)	-	crc64:99F0F96840311F4B	isoform-comment:No experimental confirmation available.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:H+zcKwbWL90wsmvD9TfWYmEbRwM559292	rogid:npId9tC7VoLN/jteoBiRbSYChPs9606	intact-crc:1F81DEA98D2E6F35|rigid:hyXrfFtNznuLrOumgbEL9f+b/iI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8IYF3-3	uniprotkb:P47041	intact:EBI-11523345|ensembl:ENSP00000363453	intact:EBI-25889|uniprotkb:D6VWC4|ensemblfungi:YJL058C	psi-mi:q8iyf3-3(display_long)|uniprotkb:TEX11(gene name)|psi-mi:TEX11(display_short)|uniprotkb:Protein ZIP4 homolog(gene name synonym)|uniprotkb:ZIP4(gene name synonym)	psi-mi:bit61_yeast(display_long)|uniprotkb:YJL058C(locus name)|uniprotkb:J1141(orf name)|uniprotkb:61 kDa binding partner of TOR2 protein(gene name synonym)|uniprotkb:BIT61(gene name)|psi-mi:BIT61(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11532252|imex:IM-24995-1037	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000120498(gene)|ensembl:ENST00000374333(transcript)|intact:EBI-742397(isoform-parent)|uniprotkb:Q8IYF3-3(isoform-parent)|entrezgene/locuslink:56159(identity)	refseq:NP_012477.1|sgd:S000003594|dip:DIP-1444N|reactome:R-SCE-1257604|reactome:R-SCE-389357|reactome:R-SCE-5218920|ensemblfungi:YJL058C(gene)|ensemblfungi:YJL058C_mRNA(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005737"(cytoplasm)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0031932"(TORC2 complex)|go:"GO:0038203"(TORC2 signaling)|go:"GO:0071944"(cell periphery)|interpro:IPR013745(HbrB-like)|reactome:R-SCE-6804757|sgd:YJL058C(identity)	-	-	crc64:99F0F96840311F4B	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:PUAMFmnm5ZV2rnJ1rhm9ZeRCixg9606	rogid:H+zcKwbWL90wsmvD9TfWYmEbRwM559292	intact-crc:8C68242FAE3CF0CD|rigid:GYyPQ0bcffXr+RKuIm21GO94QJE	false	sufficient binding region:9-925	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P47041	uniprotkb:Q8NA61-2	intact:EBI-25889|uniprotkb:D6VWC4|ensemblfungi:YJL058C	intact:EBI-11524851|ensembl:ENSP00000368249|ensembl:ENSP00000480148	psi-mi:bit61_yeast(display_long)|uniprotkb:YJL058C(locus name)|uniprotkb:J1141(orf name)|uniprotkb:61 kDa binding partner of TOR2 protein(gene name synonym)|uniprotkb:BIT61(gene name)|psi-mi:BIT61(display_short)	psi-mi:q8na61-2(display_long)|uniprotkb:CBY2(gene name)|psi-mi:CBY2(display_short)|uniprotkb:SPERT(gene name synonym)|uniprotkb:Spermatid-associated protein(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11532263|imex:IM-24995-1038	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012477.1|sgd:S000003594|dip:DIP-1444N|reactome:R-SCE-1257604|reactome:R-SCE-389357|reactome:R-SCE-5218920|ensemblfungi:YJL058C(gene)|ensemblfungi:YJL058C_mRNA(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005737"(cytoplasm)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0031932"(TORC2 complex)|go:"GO:0038203"(TORC2 signaling)|go:"GO:0071944"(cell periphery)|interpro:IPR013745(HbrB-like)|reactome:R-SCE-6804757|sgd:YJL058C(identity)	intact:EBI-741724(isoform-parent)|ensembl:ENSG00000174015(gene)|ensembl:ENST00000378966(transcript)|ensembl:ENST00000610924(transcript)|uniprotkb:Q8NA61-2(isoform-parent)|entrezgene/locuslink:220082(identity)	-	crc64:99F0F96840311F4B	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:H+zcKwbWL90wsmvD9TfWYmEbRwM559292	rogid:SogYcXGGMYRYzB9xKC5o0pEtsDs9606	intact-crc:6D8E8DE105461BC0|rigid:sLZfmeAyOhjxlAPvkl23LA8ehaE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P47041	uniprotkb:Q8NHQ1	intact:EBI-25889|uniprotkb:D6VWC4|ensemblfungi:YJL058C	intact:EBI-739624|ensembl:ENSP00000264982|ensembl:ENSP00000419231|uniprotkb:Q96B31|uniprotkb:Q9H2C3|uniprotkb:Q9H2Z1|uniprotkb:Q9H940|uniprotkb:D3DNE9|uniprotkb:B7Z5I8|uniprotkb:B7Z7E8|uniprotkb:F5GZX8	psi-mi:bit61_yeast(display_long)|uniprotkb:YJL058C(locus name)|uniprotkb:J1141(orf name)|uniprotkb:61 kDa binding partner of TOR2 protein(gene name synonym)|uniprotkb:BIT61(gene name)|psi-mi:BIT61(display_short)	psi-mi:cep70_human(display_long)|uniprotkb:CEP70(gene name)|psi-mi:CEP70(display_short)|uniprotkb:BITE(gene name synonym)|uniprotkb:p10-binding protein(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11532272|imex:IM-24995-1039	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012477.1|sgd:S000003594|dip:DIP-1444N|reactome:R-SCE-1257604|reactome:R-SCE-389357|reactome:R-SCE-5218920|ensemblfungi:YJL058C(gene)|ensemblfungi:YJL058C_mRNA(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005737"(cytoplasm)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0031932"(TORC2 complex)|go:"GO:0038203"(TORC2 signaling)|go:"GO:0071944"(cell periphery)|interpro:IPR013745(HbrB-like)|reactome:R-SCE-6804757|sgd:YJL058C(identity)	ensembl:ENSG00000114107(gene)|ensembl:ENST00000264982(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|interpro:IPR019734|interpro:IPR037692|mint:Q8NHQ1|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|ensembl:ENST00000484888(transcript)|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_077817.2|refseq:XP_016862764.1|refseq:NP_001275893.1|refseq:NP_001275894.1|refseq:NP_001275895.1|refseq:NP_001275896.1|refseq:NP_001307527.1|refseq:NP_001307529.1|entrezgene/locuslink:80321(identity)	-	crc64:99F0F96840311F4B	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:H+zcKwbWL90wsmvD9TfWYmEbRwM559292	rogid:S4yveQWcvdVtAUX65gqrJ5Dv0Mc9606	intact-crc:DDC41DB36FF0FAAB|rigid:wRL/cjvgWWdYQhzhnRhUzoozCiY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P47041	uniprotkb:Q8WWB3	intact:EBI-25889|uniprotkb:D6VWC4|ensemblfungi:YJL058C	intact:EBI-740680|ensembl:ENSP00000361276|ensembl:ENSP00000361278|ensembl:ENSP00000402890|uniprotkb:Q5QP03|uniprotkb:Q5QP04|uniprotkb:Q6WNP4|uniprotkb:Q6ZU87|uniprotkb:A8K927	psi-mi:bit61_yeast(display_long)|uniprotkb:YJL058C(locus name)|uniprotkb:J1141(orf name)|uniprotkb:61 kDa binding partner of TOR2 protein(gene name synonym)|uniprotkb:BIT61(gene name)|psi-mi:BIT61(display_short)	psi-mi:dydc1_human(display_long)|uniprotkb:DYDC1(gene name)|psi-mi:DYDC1(display_short)|uniprotkb:DPY30D1(gene name synonym)|uniprotkb:RSD9(orf name)|uniprotkb:RSD-9(orf name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11532281|imex:IM-24995-1040	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012477.1|sgd:S000003594|dip:DIP-1444N|reactome:R-SCE-1257604|reactome:R-SCE-389357|reactome:R-SCE-5218920|ensemblfungi:YJL058C(gene)|ensemblfungi:YJL058C_mRNA(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005737"(cytoplasm)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0031932"(TORC2 complex)|go:"GO:0038203"(TORC2 signaling)|go:"GO:0071944"(cell periphery)|interpro:IPR013745(HbrB-like)|reactome:R-SCE-6804757|sgd:YJL058C(identity)	refseq:NP_620167.1|ensembl:ENSG00000170788(gene)|ensembl:ENST00000372202(transcript)|ensembl:ENST00000372204(transcript)|ensembl:ENST00000421924(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0006348"|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|interpro:IPR007858(Dpy-30)|interpro:IPR037856|refseq:XP_011537636.1|refseq:XP_011537637.1|refseq:NP_001255982.1|refseq:XP_005269606.1|refseq:XP_005269607.1|entrezgene/locuslink:143241(identity)	-	crc64:99F0F96840311F4B	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:H+zcKwbWL90wsmvD9TfWYmEbRwM559292	rogid:W6GUazYFXZGHGijUBpAJ5GiRuXA9606	intact-crc:66103E7423D12CC0|rigid:jN/mk7rrsZJCN6xIQ7oIzgJAC2c	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8WXE1-3	uniprotkb:P47041	intact:EBI-11524582|ensembl:ENSP00000400930	intact:EBI-25889|uniprotkb:D6VWC4|ensemblfungi:YJL058C	psi-mi:q8wxe1-3(display_long)|uniprotkb:ATRIP(gene name)|psi-mi:ATRIP(display_short)|uniprotkb:AGS1(gene name synonym)|uniprotkb:ATM and Rad3-related-interacting protein(gene name synonym)	psi-mi:bit61_yeast(display_long)|uniprotkb:YJL058C(locus name)|uniprotkb:J1141(orf name)|uniprotkb:61 kDa binding partner of TOR2 protein(gene name synonym)|uniprotkb:BIT61(gene name)|psi-mi:BIT61(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11532290|imex:IM-24995-1041	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-747353(isoform-parent)|ensembl:ENSG00000164053(gene)|ensembl:ENST00000412052(transcript)|entrezgene/locuslink:84126(identity)	refseq:NP_012477.1|sgd:S000003594|dip:DIP-1444N|reactome:R-SCE-1257604|reactome:R-SCE-389357|reactome:R-SCE-5218920|ensemblfungi:YJL058C(gene)|ensemblfungi:YJL058C_mRNA(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005737"(cytoplasm)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0031932"(TORC2 complex)|go:"GO:0038203"(TORC2 signaling)|go:"GO:0071944"(cell periphery)|interpro:IPR013745(HbrB-like)|reactome:R-SCE-6804757|sgd:YJL058C(identity)	-	isoform-comment:No experimental confirmation available.	crc64:99F0F96840311F4B	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:NKCjy1jGZEySEhUOf8rJ6h9pyxY9606	rogid:H+zcKwbWL90wsmvD9TfWYmEbRwM559292	intact-crc:2FE85AAD33CBAAB6|rigid:CTDrD9+Jv3vAlskisDMRa4OYf/k	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P47041	uniprotkb:Q9UFD9	intact:EBI-25889|uniprotkb:D6VWC4|ensemblfungi:YJL058C	intact:EBI-10182375|uniprotkb:Q9UFQ5|uniprotkb:Q8IYP7|uniprotkb:Q9BY94|intact:EBI-28984856|ensembl:ENSP00000483386	psi-mi:bit61_yeast(display_long)|uniprotkb:YJL058C(locus name)|uniprotkb:J1141(orf name)|uniprotkb:61 kDa binding partner of TOR2 protein(gene name synonym)|uniprotkb:BIT61(gene name)|psi-mi:BIT61(display_short)	psi-mi:rim3a_human(display_long)|uniprotkb:RIMBP3(gene name)|psi-mi:RIMBP3(display_short)|uniprotkb:KIAA1666(gene name synonym)|uniprotkb:RIMBP3A(gene name synonym)|uniprotkb:RIMS-binding protein 3.1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11532319|imex:IM-24995-1044	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012477.1|sgd:S000003594|dip:DIP-1444N|reactome:R-SCE-1257604|reactome:R-SCE-389357|reactome:R-SCE-5218920|ensemblfungi:YJL058C(gene)|ensemblfungi:YJL058C_mRNA(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005737"(cytoplasm)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0031932"(TORC2 complex)|go:"GO:0038203"(TORC2 signaling)|go:"GO:0071944"(cell periphery)|interpro:IPR013745(HbrB-like)|reactome:R-SCE-6804757|sgd:YJL058C(identity)	refseq:NP_056487.1|ensembl:ENSP00000483386|ensembl:ENSG00000275793(gene)|ensembl:ENST00000619918(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007286"(spermatid development)|go:"GO:0009566"(fertilization)|go:"GO:0030156"(benzodiazepine receptor binding)|go:"GO:0045202"(synapse)|interpro:IPR001452(Src homology-3)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR035515|interpro:IPR036028|interpro:IPR036116|interpro:IPR040325|rcsb pdb:2EGE|entrezgene/locuslink:85376(identity)	-	crc64:99F0F96840311F4B	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:H+zcKwbWL90wsmvD9TfWYmEbRwM559292	rogid:iw34Gee4nqAH3pqUfCgQ6Jj++AA9606	intact-crc:2F02BFFEA6E416E5|rigid:znyYkX0tH6uay7ZGWZwtp67LFKk	false	-	sufficient binding region:838-1639	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96EY1-3	uniprotkb:P47041	intact:EBI-11526226|ensembl:ENSP00000393970	intact:EBI-25889|uniprotkb:D6VWC4|ensemblfungi:YJL058C	psi-mi:q96ey1-3(display_long)|uniprotkb:DnaJ protein Tid-1(gene name synonym)|uniprotkb:HCA57(gene name synonym)|uniprotkb:Hepatocellular carcinoma-associated antigen 57(gene name synonym)|uniprotkb:TID1(gene name synonym)|uniprotkb:Tumorous imaginal discs protein Tid56 homolog(gene name synonym)|uniprotkb:DNAJA3(gene name)|psi-mi:DNAJA3(display_short)	psi-mi:bit61_yeast(display_long)|uniprotkb:YJL058C(locus name)|uniprotkb:J1141(orf name)|uniprotkb:61 kDa binding partner of TOR2 protein(gene name synonym)|uniprotkb:BIT61(gene name)|psi-mi:BIT61(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11532299|imex:IM-24995-1042	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-356767(isoform-parent)|ensembl:ENSG00000103423(gene)|ensembl:ENST00000431375(transcript)|uniprotkb:Q96EY1-3(isoform-parent)|entrezgene/locuslink:9093(identity)	refseq:NP_012477.1|sgd:S000003594|dip:DIP-1444N|reactome:R-SCE-1257604|reactome:R-SCE-389357|reactome:R-SCE-5218920|ensemblfungi:YJL058C(gene)|ensemblfungi:YJL058C_mRNA(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005737"(cytoplasm)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0031932"(TORC2 complex)|go:"GO:0038203"(TORC2 signaling)|go:"GO:0071944"(cell periphery)|interpro:IPR013745(HbrB-like)|reactome:R-SCE-6804757|sgd:YJL058C(identity)	-	isoform-comment:"Ref.3 (BAG58345) sequence is in conflict in position: 33:Y->H."	crc64:99F0F96840311F4B	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:nMH4IaOZYO5w5bh+cdX4LoPSisc9606	rogid:H+zcKwbWL90wsmvD9TfWYmEbRwM559292	intact-crc:7CB201768ADC2669|rigid:BIUcqDzPWeKiECjMQJFdyG5lduk	false	sufficient binding region:60-300	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P47041	uniprotkb:Q9P286	intact:EBI-25889|uniprotkb:D6VWC4|ensemblfungi:YJL058C	intact:EBI-741896|ensembl:ENSP00000322957|ensembl:ENSP00000367679|ensembl:ENSP00000367686|intact:EBI-1051061|uniprotkb:A8K5T6|uniprotkb:D3DW14|uniprotkb:Q5W115|uniprotkb:Q8TB93|uniprotkb:Q9BX09|uniprotkb:Q9ULF6	psi-mi:bit61_yeast(display_long)|uniprotkb:YJL058C(locus name)|uniprotkb:J1141(orf name)|uniprotkb:61 kDa binding partner of TOR2 protein(gene name synonym)|uniprotkb:BIT61(gene name)|psi-mi:BIT61(display_short)	psi-mi:pak5_human(display_long)|uniprotkb:PAK5(gene name)|psi-mi:PAK5(display_short)|uniprotkb:KIAA1264(gene name synonym)|uniprotkb:PAK7(gene name synonym)|uniprotkb:p21-activated kinase 5(gene name synonym)|uniprotkb:p21-activated kinase 7(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11532310|imex:IM-24995-1043	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012477.1|sgd:S000003594|dip:DIP-1444N|reactome:R-SCE-1257604|reactome:R-SCE-389357|reactome:R-SCE-5218920|ensemblfungi:YJL058C(gene)|ensemblfungi:YJL058C_mRNA(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005737"(cytoplasm)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0031932"(TORC2 complex)|go:"GO:0038203"(TORC2 signaling)|go:"GO:0071944"(cell periphery)|interpro:IPR013745(HbrB-like)|reactome:R-SCE-6804757|sgd:YJL058C(identity)	ensembl:ENSG00000101349(gene)|go:"GO:0045202"(synapse)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR028754|interpro:IPR033923|interpro:IPR036936|rcsb pdb:2F57|reactome:R-HSA-428540|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013405|reactome:R-HSA-9013407|go:"GO:0043408"(regulation of MAPK cascade)|ensembl:ENST00000353224(transcript)|ensembl:ENST00000378423(transcript)|ensembl:ENST00000378429(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007165"(signal transduction)|go:"GO:0007612"(learning)|go:"GO:0007613"(memory)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016477"(cell migration)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0035556"(intracellular signal transduction)|refseq:NP_065074.1|refseq:NP_817127.1|refseq:XP_016883449.1|refseq:XP_016883450.1|refseq:XP_016883451.1|refseq:XP_016883452.1|refseq:XP_016883453.1|refseq:XP_016883454.1|entrezgene/locuslink:57144(identity)	-	crc64:99F0F96840311F4B	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2017/06/28	rogid:H+zcKwbWL90wsmvD9TfWYmEbRwM559292	rogid:xxNDwmHn4jv8toBmviGjFwBU32E9606	intact-crc:BB848ECB47AF8508|rigid:WEa7pLLKEqJ07g0CUxe3Q2BVVu0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q16637-3	uniprotkb:P47086	intact:EBI-395447|ensembl:ENSP00000424926|ensembl:ENSP00000486152|ensembl:ENSP00000487015|ensembl:ENSP00000487029|intact:EBI-8628183|intact:MINT-95595	intact:EBI-26299|uniprotkb:D6VWI7|uniprotkb:Q6Q5N5|ensemblfungi:YJR011C	psi-mi:q16637-3(display_long)|uniprotkb:Iso7-SMN(isoform synonym)|uniprotkb:SMN1(gene name)|psi-mi:SMN1(display_short)|uniprotkb:SMN2(gene name)|psi-mi:SMN2(display_short)|uniprotkb:SMN(gene name synonym)|uniprotkb:SMNT(gene name synonym)|uniprotkb:SMNC(gene name synonym)|uniprotkb:Component of gems 1(gene name synonym)|uniprotkb:Gemin-1(gene name synonym)	psi-mi:yjy1_yeast(display_long)|uniprotkb:J1438(orf name)|uniprotkb:YJR83.26(orf name)|uniprotkb:YJR011C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11532381|imex:IM-24995-1050	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-395421(smn_human)|ensembl:ENSG00000275349(gene)|ensembl:ENST00000506163(transcript)|ensembl:ENST00000626847(transcript)|ensembl:ENST00000628353(transcript)|ensembl:ENST00000628642(transcript)|ensembl:ENSG00000172062(gene)|ensembl:ENSG00000205571(gene)|ensembl:ENSG00000273772(gene)|uniprotkb:Q16637-3(isoform-parent)|entrezgene/locuslink:6607(identity)	sgd:S000003772|refseq:NP_012545.1|mint:P47086|dip:DIP-5694N|ensemblfungi:YJR011C(gene)|ensemblfungi:YJR011C_mRNA(transcript)|sgd:YJR011C(identity)	-	isoform-comment:Thought to be a non-functional protein that lacks the capacity to oligomerize and thus cannot interact with Sm proteins. Primarily derived from SMN2 gene.	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:ICA63eidVxJ219M+YZJ20zNh+xU9606	rogid:b7YXohJEN6FMN8gYKAKboZQkxvQ559292	intact-crc:DDE42408EB2BADAB|rigid:i7drGLsuBejxbIWgVhYb8wIJ0Ls	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q16637	uniprotkb:P47086	intact:EBI-395421|uniprotkb:Q13119|uniprotkb:Q549U5|uniprotkb:Q96J51|ensembl:ENSP00000305857|uniprotkb:A8K0V4|ensembl:ENSP00000370083|ensembl:ENSP00000370117|ensembl:ENSP00000370119|ensembl:ENSP00000479920|ensembl:ENSP00000482966|ensembl:ENSP00000483515|ensembl:ENSP00000483819|ensembl:ENSP00000487206|ensembl:ENSP00000487421	intact:EBI-26299|uniprotkb:D6VWI7|uniprotkb:Q6Q5N5|ensemblfungi:YJR011C	psi-mi:smn_human(display_long)|uniprotkb:SMN1(gene name)|psi-mi:SMN1(display_short)|uniprotkb:SMN(gene name synonym)|uniprotkb:SMNT(gene name synonym)|uniprotkb:SMN2(gene name)|psi-mi:SMN2(display_short)|uniprotkb:SMNC(gene name synonym)|uniprotkb:Component of gems 1(gene name synonym)|uniprotkb:Gemin-1(gene name synonym)	psi-mi:yjy1_yeast(display_long)|uniprotkb:J1438(orf name)|uniprotkb:YJR83.26(orf name)|uniprotkb:YJR011C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11532372|imex:IM-24995-1049	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000335.1|refseq:NP_059107.1|refseq:NP_075012.1|refseq:NP_075013.1|refseq:NP_075014.1|refseq:NP_075015.1|ensembl:ENSG00000172062(gene)|ensembl:ENSG00000205571(gene)|ensembl:ENSG00000273772(gene)|ensembl:ENSG00000275349(gene)|ensembl:ENSG00000277773(gene)|ensembl:ENST00000351205(transcript)|ensembl:ENST00000380707(transcript)|ensembl:ENST00000380741(transcript)|ensembl:ENST00000380743(transcript)|ensembl:ENST00000614610(transcript)|ensembl:ENST00000618251(transcript)|ensembl:ENST00000618661(transcript)|ensembl:ENST00000622739(transcript)|ensembl:ENST00000627341(transcript)|ensembl:ENST00000629122(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0007399"(nervous system development)|go:"GO:0015030"(Cajal body)|go:"GO:0016604"(nuclear body)|go:"GO:0030018"(Z disc)|go:"GO:0030424"(axon)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043204"(perikaryon)|go:"GO:0097504"(Gemini of coiled bodies)|interpro:IPR002999(Tudor)|interpro:IPR010304(Survival motor neuron)|mint:Q16637|rcsb pdb:1G5V|rcsb pdb:1MHN|rcsb pdb:2LEH|rcsb pdb:4A4E|rcsb pdb:4A4G|rcsb pdb:4GLI|rcsb pdb:4QQ6|rcsb pdb:5XJL|go:"GO:0034719"(SMN-Sm protein complex)|rcsb pdb:5XJQ|rcsb pdb:5XJR|rcsb pdb:5XJS|rcsb pdb:5XJT|rcsb pdb:5XJU|reactome:R-HSA-191859|go:"GO:0032797"(SMN complex)|refseq:NP_001284644.1|ensembl:ENSP00000305857|ensembl:ENSP00000370083|ensembl:ENSP00000370117|ensembl:ENST00000380742|ensembl:ENSP00000370118|ensembl:ENSP00000370119|ensembl:ENST00000503079|ensembl:ENSP00000428128|ensembl:ENST00000506163|ensembl:ENSP00000424926|ensembl:ENST00000611442|ensembl:ENSP00000483768|ensembl:ENST00000614240|ensembl:ENSP00000479279|ensembl:ENSP00000479920|ensembl:ENST00000614773|ensembl:ENSP00000481427|ensembl:ENSP00000483515|ensembl:ENSP00000483819|ensembl:ENST00000622158|ensembl:ENSP00000480906|ensembl:ENSP00000482966|ensembl:ENST00000624634|ensembl:ENSP00000485595|ensembl:ENST00000626847|ensembl:ENSP00000486152|ensembl:ENSP00000487421|ensembl:ENST00000628353|ensembl:ENSP00000487029|ensembl:ENST00000628642|ensembl:ENSP00000487015|ensembl:ENSP00000487206|refseq:XP_016865275.1|dip:DIP-31309N|entrezgene/locuslink:6607(identity)	sgd:S000003772|refseq:NP_012545.1|mint:P47086|dip:DIP-5694N|ensemblfungi:YJR011C(gene)|ensemblfungi:YJR011C_mRNA(transcript)|sgd:YJR011C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:QGivm7E8suciCWXO4l0zCUzCl2g9606	rogid:b7YXohJEN6FMN8gYKAKboZQkxvQ559292	intact-crc:2E8EE24D0263A4AC|rigid:ZQ6NMREfPqDMd+YBfYo0Pj7l2A0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P47086	uniprotkb:P78356-2	intact:EBI-26299|uniprotkb:D6VWI7|uniprotkb:Q6Q5N5|ensemblfungi:YJR011C	intact:EBI-11532361	psi-mi:yjy1_yeast(display_long)|uniprotkb:J1438(orf name)|uniprotkb:YJR83.26(orf name)|uniprotkb:YJR011C(locus name)	psi-mi:p78356-2(display_long)|uniprotkb:PIP4K2B(gene name)|psi-mi:PIP4K2B(display_short)|uniprotkb:1-phosphatidylinositol 5-phosphate 4-kinase 2-beta(gene name synonym)|uniprotkb:Diphosphoinositide kinase 2-beta(gene name synonym)|uniprotkb:PIP5K2B(gene name synonym)|uniprotkb:Phosphatidylinositol 5-phosphate 4-kinase type II beta(gene name synonym)|uniprotkb:"PtdIns(5)P-4-kinase isoform 2-beta"(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11532359|imex:IM-24995-1048	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003772|refseq:NP_012545.1|mint:P47086|dip:DIP-5694N|ensemblfungi:YJR011C(gene)|ensemblfungi:YJR011C_mRNA(transcript)|sgd:YJR011C(identity)	intact:EBI-947090(isoform-parent)|uniprotkb:P78356-2(isoform-parent)|entrezgene/locuslink:8396(identity)	-	-	isoform-comment:No experimental confirmation available.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:b7YXohJEN6FMN8gYKAKboZQkxvQ559292	rogid:vM046yHfiRTiHTWlLYpaqEegf0o9606	intact-crc:15A164285F2EB757|rigid:u9P+H3Bj4VVQyFi4wgifyu5XH0g	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UJV3-2	uniprotkb:P47041	intact:EBI-10172526|ensembl:ENSP00000413976	intact:EBI-25889|uniprotkb:D6VWC4|ensemblfungi:YJL058C	psi-mi:q9ujv3-2(display_long)|uniprotkb:RING-type E3 ubiquitin transferase MID2(gene name synonym)|uniprotkb:FXY2(gene name synonym)|uniprotkb:Midin-2(gene name synonym)|uniprotkb:Midline defect 2(gene name synonym)|uniprotkb:Midline-2(gene name synonym)|uniprotkb:RING finger protein 60(gene name synonym)|uniprotkb:RNF60(gene name synonym)|uniprotkb:TRIM1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 1(gene name synonym)|uniprotkb:MID2(gene name)|psi-mi:MID2(display_short)	psi-mi:bit61_yeast(display_long)|uniprotkb:YJL058C(locus name)|uniprotkb:J1141(orf name)|uniprotkb:61 kDa binding partner of TOR2 protein(gene name synonym)|uniprotkb:BIT61(gene name)|psi-mi:BIT61(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11532330|imex:IM-24995-1045	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-751983(isoform-parent)|uniprotkb:Q9UJV3-2(isoform-parent)|ensembl:ENSG00000080561(gene)|ensembl:ENST00000443968(transcript)|entrezgene/locuslink:11043(identity)	refseq:NP_012477.1|sgd:S000003594|dip:DIP-1444N|reactome:R-SCE-1257604|reactome:R-SCE-389357|reactome:R-SCE-5218920|ensemblfungi:YJL058C(gene)|ensemblfungi:YJL058C_mRNA(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005737"(cytoplasm)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0031932"(TORC2 complex)|go:"GO:0038203"(TORC2 signaling)|go:"GO:0071944"(cell periphery)|interpro:IPR013745(HbrB-like)|reactome:R-SCE-6804757|sgd:YJL058C(identity)	-	-	crc64:99F0F96840311F4B	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:/FJ+V2H7SaWon7caUWkEkmHFVxQ9606	rogid:H+zcKwbWL90wsmvD9TfWYmEbRwM559292	intact-crc:DADC9A08915F8E5B|rigid:hf9JTYnvR2caA0SqjlDsK8X6LhY	false	sufficient binding region:21-705	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P47086	uniprotkb:Q9C0F1	intact:EBI-26299|uniprotkb:D6VWI7|uniprotkb:Q6Q5N5|ensemblfungi:YJR011C	intact:EBI-744115|uniprotkb:A8K8W9|uniprotkb:B3KT53|uniprotkb:Q8IXZ4|uniprotkb:A8MW11|uniprotkb:D3DP42|ensembl:ENSP00000296519|ensembl:ENSP00000380009|ensembl:ENSP00000423153	psi-mi:yjy1_yeast(display_long)|uniprotkb:J1438(orf name)|uniprotkb:YJR83.26(orf name)|uniprotkb:YJR011C(locus name)	psi-mi:cep44_human(display_long)|uniprotkb:HBV PreS1-transactivated protein 3(gene name synonym)|uniprotkb:CEP44(gene name)|psi-mi:CEP44(display_short)|uniprotkb:KIAA1712(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11532390|imex:IM-24995-1051	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003772|refseq:NP_012545.1|mint:P47086|dip:DIP-5694N|ensemblfungi:YJR011C(gene)|ensemblfungi:YJR011C_mRNA(transcript)|sgd:YJR011C(identity)	refseq:NP_001035247.1|refseq:NP_001138786.1|refseq:XP_011530587.1|refseq:XP_011530588.1|refseq:XP_011530589.1|refseq:XP_016864143.1|refseq:XP_016864144.1|ensembl:ENSG00000164118(gene)|ensembl:ENST00000296519(transcript)|ensembl:ENST00000396791(transcript)|ensembl:ENST00000503780(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007099"(centriole replication)|go:"GO:0008017"(microtubule binding)|go:"GO:0010457"(centriole-centriole cohesion)|go:"GO:0030496"(midbody)|interpro:IPR029157|interpro:IPR033603|mint:Q9C0F1|entrezgene/locuslink:80817(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:b7YXohJEN6FMN8gYKAKboZQkxvQ559292	rogid:gDTC64oDhudGdsssC7v+suIHZkA9606	intact-crc:9714FD94F4C4D55B|rigid:IlkQ17p7yZ9vPCBu6RWm03zPPBQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9Y2D8	uniprotkb:P47041	intact:EBI-2212028|uniprotkb:B4DFE3|uniprotkb:J3KR02|uniprotkb:A8K8W0|uniprotkb:D3DT13|uniprotkb:Q6P2P8|uniprotkb:Q6ULS1|uniprotkb:Q7L168|uniprotkb:Q9UIX0|intact:EBI-10964529|ensembl:ENSP00000340279	intact:EBI-25889|uniprotkb:D6VWC4|ensemblfungi:YJL058C	psi-mi:adip_human(display_long)|uniprotkb:SSX2IP(gene name)|psi-mi:SSX2IP(display_short)|uniprotkb:KIAA0923(gene name synonym)|uniprotkb:Afadin DIL domain-interacting protein(gene name synonym)|uniprotkb:SSX2-interacting protein(gene name synonym)	psi-mi:bit61_yeast(display_long)|uniprotkb:YJL058C(locus name)|uniprotkb:J1141(orf name)|uniprotkb:61 kDa binding partner of TOR2 protein(gene name synonym)|uniprotkb:BIT61(gene name)|psi-mi:BIT61(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11532350|imex:IM-24995-1047	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011538912.1|refseq:NP_001159765.1|refseq:NP_001159766.1|refseq:NP_001159767.1|refseq:NP_001159889.1|refseq:NP_054740.3|refseq:XP_005270484.1|refseq:XP_005270485.1|refseq:XP_006710394.1|refseq:XP_016855723.1|ensembl:ENSG00000117155(gene)|ensembl:ENST00000342203(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005912"(adherens junction)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031252"(cell leading edge)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0035735"(intraciliary transport involved in cilium assembly)|go:"GO:0036064"(ciliary basal body)|go:"GO:0060271"(cilium assembly)|go:"GO:2000145"(regulation of cell motility)|interpro:IPR021622|mint:Q9Y2D8|entrezgene/locuslink:117178(identity)	refseq:NP_012477.1|sgd:S000003594|dip:DIP-1444N|reactome:R-SCE-1257604|reactome:R-SCE-389357|reactome:R-SCE-5218920|ensemblfungi:YJL058C(gene)|ensemblfungi:YJL058C_mRNA(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005737"(cytoplasm)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0031932"(TORC2 complex)|go:"GO:0038203"(TORC2 signaling)|go:"GO:0071944"(cell periphery)|interpro:IPR013745(HbrB-like)|reactome:R-SCE-6804757|sgd:YJL058C(identity)	-	-	crc64:99F0F96840311F4B	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:E0VeMRF9SrpQKSJFP01XEbMjeF89606	rogid:H+zcKwbWL90wsmvD9TfWYmEbRwM559292	intact-crc:35DFE9717E12F1ED|rigid:GsJ5roI+fl2JX8Dy+oaZhNpR7Fc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UKT9	uniprotkb:P47041	intact:EBI-747204|uniprotkb:Q8WWQ9|uniprotkb:Q8WWR0|uniprotkb:Q8WWR1|uniprotkb:Q8WWR2|uniprotkb:Q8WWR3|uniprotkb:Q8N574|uniprotkb:B4DVV5|uniprotkb:Q69BL6|uniprotkb:Q69BL7|uniprotkb:Q69BL8|uniprotkb:Q69BL9|uniprotkb:Q69BM0|uniprotkb:Q69BM1|uniprotkb:Q69BM2|uniprotkb:Q69BM3|uniprotkb:Q69BM5|ensembl:ENSP00000344544	intact:EBI-25889|uniprotkb:D6VWC4|ensemblfungi:YJL058C	psi-mi:ikzf3_human(display_long)|uniprotkb:ZNFN1A3(gene name synonym)|uniprotkb:Ikaros family zinc finger protein 3(gene name synonym)|uniprotkb:IKZF3(gene name)|psi-mi:IKZF3(display_short)	psi-mi:bit61_yeast(display_long)|uniprotkb:YJL058C(locus name)|uniprotkb:J1141(orf name)|uniprotkb:61 kDa binding partner of TOR2 protein(gene name synonym)|uniprotkb:BIT61(gene name)|psi-mi:BIT61(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11532341|imex:IM-24995-1046	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001271443.1|refseq:NP_001271444.1|refseq:NP_036613.2|refseq:NP_899051.1|refseq:NP_899052.1|refseq:NP_899053.1|refseq:NP_899054.1|refseq:NP_899055.1|refseq:NP_001271445.1|refseq:NP_001244337.1|refseq:NP_001244338.1|refseq:NP_001244339.1|refseq:NP_001244340.1|refseq:NP_001244341.1|refseq:NP_001244342.1|refseq:NP_001244343.1|ensembl:ENSG00000161405(gene)|ensembl:ENST00000346872(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007498"(mesoderm development)|go:"GO:0009617"(response to bacterium)|go:"GO:0030888"(regulation of B cell proliferation)|go:"GO:0042113"(B cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045577"(regulation of B cell differentiation)|go:"GO:0045619"(regulation of lymphocyte differentiation)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|go:"GO:0046872"(metal ion binding)|dip:DIP-56975N|entrezgene/locuslink:22806(identity)	refseq:NP_012477.1|sgd:S000003594|dip:DIP-1444N|reactome:R-SCE-1257604|reactome:R-SCE-389357|reactome:R-SCE-5218920|ensemblfungi:YJL058C(gene)|ensemblfungi:YJL058C_mRNA(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005737"(cytoplasm)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0031932"(TORC2 complex)|go:"GO:0038203"(TORC2 signaling)|go:"GO:0071944"(cell periphery)|interpro:IPR013745(HbrB-like)|reactome:R-SCE-6804757|sgd:YJL058C(identity)	-	-	crc64:99F0F96840311F4B	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:2Kp6LefSLfK5VIiE6DmQusFIfMY9606	rogid:H+zcKwbWL90wsmvD9TfWYmEbRwM559292	intact-crc:5DA3710DBD946E37|rigid:Jn6qVPw1QCEseCWRZX5P5z2dM34	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P47086	uniprotkb:Q9NWT6	intact:EBI-26299|uniprotkb:D6VWI7|uniprotkb:Q6Q5N5|ensemblfungi:YJR011C	intact:EBI-745632|uniprotkb:Q969Q7|uniprotkb:Q9NPV5|uniprotkb:Q5W147|ensembl:ENSP00000299163|uniprotkb:D3DR69	psi-mi:yjy1_yeast(display_long)|uniprotkb:J1438(orf name)|uniprotkb:YJR83.26(orf name)|uniprotkb:YJR011C(locus name)	psi-mi:hif1n_human(display_long)|uniprotkb:Hypoxia-inducible factor asparagine hydroxylase(gene name synonym)|uniprotkb:Factor inhibiting HIF-1(gene name synonym)|uniprotkb:HIF1AN(gene name)|psi-mi:HIF1AN(display_short)|uniprotkb:FIH1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11532399|imex:IM-24995-1052	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003772|refseq:NP_012545.1|mint:P47086|dip:DIP-5694N|ensemblfungi:YJR011C(gene)|ensemblfungi:YJR011C_mRNA(transcript)|sgd:YJR011C(identity)	refseq:NP_060372.2|ensembl:ENSG00000166135(gene)|ensembl:ENST00000299163(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0036138"(peptidyl-histidine hydroxylation)|go:"GO:0036139"(peptidyl-histidine dioxygenase activity)|go:"GO:0036140"(peptidyl-asparagine 3-dioxygenase activity)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0042265"(peptidyl-asparagine hydroxylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0102113"(hypoxia-inducible factor-asparagine oxygenase activity)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027445|interpro:IPR027452|interpro:IPR041667|mint:Q9NWT6|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1H2N|rcsb pdb:1IZ3|rcsb pdb:1MZE|rcsb pdb:1MZF|rcsb pdb:1YCI|rcsb pdb:2CGN|rcsb pdb:2CGO|rcsb pdb:2ILM|rcsb pdb:2W0X|rcsb pdb:2WA3|rcsb pdb:2WA4|rcsb pdb:2XUM|rcsb pdb:2Y0I|rcsb pdb:2YC0|rcsb pdb:2YDE|rcsb pdb:3D8C|rcsb pdb:3KCX|rcsb pdb:3KCY|rcsb pdb:3OD4|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:4AI8|rcsb pdb:4B7E|rcsb pdb:4B7K|rcsb pdb:4BIO|rcsb pdb:4JAA|rcsb pdb:4NR1|rcsb pdb:4Z1V|rcsb pdb:4Z2W|rcsb pdb:5JWK|rcsb pdb:5JWL|rcsb pdb:5JWP|rcsb pdb:5OP6|rcsb pdb:6H9J|rcsb pdb:6HA6|rcsb pdb:6HC8|rcsb pdb:6HKP|rcsb pdb:6HL5|rcsb pdb:6HL6|rcsb pdb:6RUJ|reactome:R-HSA-1234174|rcsb pdb:5OP8|rcsb pdb:5OPC|dip:DIP-35527N|entrezgene/locuslink:55662(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:b7YXohJEN6FMN8gYKAKboZQkxvQ559292	rogid:lvPtfqlB1+hOcdCAwcopj/Yl+3Y9606	intact-crc:751BE6C50B4409D1|rigid:nR1XPi9ZWReYQ/dZTk2ZSoxjNy4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UJW9	uniprotkb:P47086	intact:EBI-748621|uniprotkb:Q96CQ2|uniprotkb:B3KQB3|ensembl:ENSP00000325414|ensembl:ENSP00000375882	intact:EBI-26299|uniprotkb:D6VWI7|uniprotkb:Q6Q5N5|ensemblfungi:YJR011C	psi-mi:srtd3_human(display_long)|uniprotkb:Replication protein-binding trans-activator(gene name synonym)|uniprotkb:SERTAD3(gene name)|psi-mi:SERTAD3(display_short)|uniprotkb:RBT1(gene name synonym)	psi-mi:yjy1_yeast(display_long)|uniprotkb:J1438(orf name)|uniprotkb:YJR83.26(orf name)|uniprotkb:YJR011C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11532408|imex:IM-24995-1053	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006723242.1|refseq:NP_037500.2|refseq:NP_976219.1|refseq:XP_005258889.1|ensembl:ENSG00000167565(gene)|ensembl:ENST00000322354(transcript)|ensembl:ENST00000392028(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR009263(SERTA)|interpro:IPR039585|entrezgene/locuslink:29946(identity)	sgd:S000003772|refseq:NP_012545.1|mint:P47086|dip:DIP-5694N|ensemblfungi:YJR011C(gene)|ensemblfungi:YJR011C_mRNA(transcript)|sgd:YJR011C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:zraVKcqHA7SNRrMV50iyPK6O7ok9606	rogid:b7YXohJEN6FMN8gYKAKboZQkxvQ559292	intact-crc:C9214E1F498AD0B9|rigid:lPET/7vwNIdmGxP+T7v5gnf7vjE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96BA8	uniprotkb:P47088	intact:EBI-6942903|ensembl:ENSP00000481956|intact:MINT-268046|intact:MINT-8162577|uniprotkb:Q8N2D5|uniprotkb:Q96CP0	intact:EBI-26307|uniprotkb:D6VWI9|uniprotkb:E9P8R4|ensemblfungi:YJR013W	psi-mi:cr3l1_human(display_long)|uniprotkb:CREB3L1(gene name)|psi-mi:CREB3L1(display_short)|uniprotkb:OASIS(gene name synonym)|uniprotkb:PSEC0238(orf name)|uniprotkb:Old astrocyte specifically-induced substance(gene name synonym)	psi-mi:gpi14_yeast(display_long)|uniprotkb:GPI mannosyltransferase I(gene name synonym)|uniprotkb:Glycosylphosphatidylinositol-anchor biosynthesis protein 14(gene name synonym)|uniprotkb:YJR013W(locus name)|uniprotkb:J1444(orf name)|uniprotkb:YJR83.11(orf name)|uniprotkb:GPI14(gene name)|psi-mi:GPI14(display_short)|uniprotkb:PMH1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11532417|imex:IM-24995-1054	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157613(gene)|ensembl:ENST00000621158(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0070278"(extracellular matrix constituent secretion)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029805|mint:Q96BA8|reactome:R-HSA-8874211|refseq:NP_443086.1|entrezgene/locuslink:90993(identity)	refseq:NP_012547.2|sgd:S000003774|interpro:IPR007704(Mannosyltransferase, DXD)|ensemblfungi:YJR013W(gene)|ensemblfungi:YJR013W_mRNA(transcript)|go:"GO:0004376"(glycolipid mannosyltransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006506"(GPI anchor biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0051751"(alpha-1,4-mannosyltransferase activity)|go:"GO:1990529"(glycosylphosphatidylinositol-mannosyltransferase I complex)|sgd:YJR013W(identity)	-	comment:mint|function:"Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE"	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:sMWUFmBeBBCO+T0Y2CuB/un1lBg9606	rogid:I8WI1aDIsik8nbDq7V/vf4UY9oQ559292	intact-crc:0178CD3ECF29C78D|rigid:t6bn5S4A1t6XXfXKIRvCY7ja3UE	false	-	sufficient binding region:99-403	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O43765	uniprotkb:P47094	intact:EBI-347996|ensembl:ENSP00000221566|ensembl:ENSP00000503397|ensembl:ENSP00000504495|uniprotkb:Q9BTZ9|intact:EBI-1045243|uniprotkb:Q6FIA9|uniprotkb:D6W610	intact:EBI-26323|ensemblfungi:YJR023C	psi-mi:sgta_human(display_long)|uniprotkb:SGTA(gene name)|psi-mi:SGTA(display_short)|uniprotkb:SGT(gene name synonym)|uniprotkb:Alpha-SGT(gene name synonym)|uniprotkb:Vpu-binding protein(gene name synonym)|uniprotkb:SGT1(gene name synonym)	psi-mi:yjz3_yeast(display_long)|uniprotkb:J1470(orf name)|uniprotkb:YJR83.19(orf name)|uniprotkb:YJR023C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11532429|imex:IM-24995-1055	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:4CPG|rcsb pdb:4GOD|rcsb pdb:4GOE|rcsb pdb:4GOF|reactome:R-HSA-9609523|rcsb pdb:2VYI|ensembl:ENSG00000104969(gene)|ensembl:ENST00000221566(transcript)|ensembl:ENST00000676943(transcript)|ensembl:ENST00000677149(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072380"(TRC complex)|go:"GO:0098850"(extrinsic component of synaptic vesicle membrane)|go:"GO:1903070"(negative regulation of ER-associated ubiquitin-dependent protein catabolic process)|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)|go:"GO:1903646"(positive regulation of chaperone-mediated protein folding)|go:"GO:1904288"(BAT3 complex binding)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR032374|mint:O43765|refseq:XP_011526480.1|refseq:NP_003012.1|entrezgene/locuslink:6449(identity)	sgd:S000003784|dip:DIP-2641N|ensemblfungi:YJR023C(gene)|ensemblfungi:YJR023C_mRNA(transcript)|go:"GO:0016021"(integral component of membrane)|sgd:YJR023C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:r/Cyj4UJk/cS8QdrbjhTZMPCigI9606	rogid:lOcQ5QyAEpXz/uROltQZ2quCgzI559292	intact-crc:BA6213F8D96442F7|rigid:xIqeVpaNWZvv+ifhaApFY44L+H4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9HCM9-2	uniprotkb:P47107	intact:EBI-11523450|ensembl:ENSP00000365847|ensembl:ENSP00000373095|ensembl:ENSP00000373097|ensembl:ENSP00000379797|ensembl:ENSP00000379800|ensembl:ENSP00000383486|ensembl:ENSP00000387445|ensembl:ENSP00000389198|ensembl:ENSP00000389852|ensembl:ENSP00000392130|ensembl:ENSP00000394353|ensembl:ENSP00000396986|ensembl:ENSP00000398956|ensembl:ENSP00000401071|ensembl:ENSP00000401184|ensembl:ENSP00000404340|ensembl:ENSP00000404904|ensembl:ENSP00000411582|ensembl:ENSP00000412743|ensembl:ENSP00000414525|ensembl:ENSP00000415259	intact:EBI-2344909|uniprotkb:D6VWL0|ensemblfungi:YJR039W	psi-mi:q9hcm9-2(display_long)|uniprotkb:TRIM39(gene name)|psi-mi:TRIM39(display_short)|uniprotkb:RING finger protein 23(gene name synonym)|uniprotkb:RNF23(gene name synonym)|uniprotkb:TFP(gene name synonym)|uniprotkb:Testis-abundant finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 39(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM39(gene name synonym)|uniprotkb:TIM39beta(isoform synonym)	psi-mi:yj09_yeast(display_long)|uniprotkb:J1614(orf name)|uniprotkb:YJR039W(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11532438|imex:IM-24995-1056	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-739510(isoform-parent)|ensembl:ENSG00000204599(gene)|ensembl:ENSG00000206495(gene)|ensembl:ENSG00000224994(gene)|ensembl:ENSG00000226437(gene)|ensembl:ENSG00000229929(gene)|ensembl:ENSG00000230308(gene)|ensembl:ENSG00000232839(gene)|ensembl:ENST00000376659(transcript)|ensembl:ENST00000383601(transcript)|ensembl:ENST00000383603(transcript)|ensembl:ENST00000396548(transcript)|ensembl:ENST00000396551(transcript)|ensembl:ENST00000400644(transcript)|ensembl:ENST00000414015(transcript)|ensembl:ENST00000419790(transcript)|ensembl:ENST00000430502(transcript)|ensembl:ENST00000431272(transcript)|ensembl:ENST00000433900(transcript)|ensembl:ENST00000438076(transcript)|ensembl:ENST00000438859(transcript)|ensembl:ENST00000440117(transcript)|ensembl:ENST00000443109(transcript)|ensembl:ENST00000446397(transcript)|ensembl:ENST00000449318(transcript)|ensembl:ENST00000450778(transcript)|ensembl:ENST00000451132(transcript)|ensembl:ENST00000452705(transcript)|ensembl:ENST00000458607(transcript)|uniprotkb:Q9HCM9-2(isoform-parent)|entrezgene/locuslink:56658(identity)	sgd:S000003800|refseq:NP_012573.1|ensemblfungi:YJR039W(gene)|ensemblfungi:YJR039W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|sgd:YJR039W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:UfSn2+IVRxtGomVeDGdZpL7mz5I9606	rogid:79jOtKfgrrdJYmThBSRaCtpPF5A559292	intact-crc:322E3EA36E1A5479|rigid:0feV6Q6LdnFm13FzOqFPEOK8Dyg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96BA8	uniprotkb:P47111	intact:EBI-6942903|ensembl:ENSP00000481956|intact:MINT-268046|intact:MINT-8162577|uniprotkb:Q8N2D5|uniprotkb:Q96CP0	intact:EBI-25497|uniprotkb:D6VWL5|ensemblfungi:YJR044C	psi-mi:cr3l1_human(display_long)|uniprotkb:CREB3L1(gene name)|psi-mi:CREB3L1(display_short)|uniprotkb:OASIS(gene name synonym)|uniprotkb:PSEC0238(orf name)|uniprotkb:Old astrocyte specifically-induced substance(gene name synonym)	psi-mi:vps55_yeast(display_long)|uniprotkb:J1637(orf name)|uniprotkb:YJR044C(locus name)|uniprotkb:VPS55(gene name)|psi-mi:VPS55(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11532448|imex:IM-24995-1057	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157613(gene)|ensembl:ENST00000621158(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0070278"(extracellular matrix constituent secretion)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029805|mint:Q96BA8|reactome:R-HSA-8874211|refseq:NP_443086.1|entrezgene/locuslink:90993(identity)	sgd:S000003805|refseq:NP_012578.3|dip:DIP-7667N|mint:P47111|ensemblfungi:YJR044C(gene)|ensemblfungi:YJR044C_mRNA(transcript)|go:"GO:0005768"(endosome)|go:"GO:0005770"(late endosome)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0034424"(Vps55/Vps68 complex)|go:"GO:2000009"(negative regulation of protein localization to cell surface)|interpro:IPR007262(Vacuolar protein sorting 55)|sgd:YJR044C(identity)	-	comment:mint|function:"Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE"	crc64:1F207E62F093FC6D	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:sMWUFmBeBBCO+T0Y2CuB/un1lBg9606	rogid:J23lc6VW+GZsH/Tu+ukXF5QauPg559292	intact-crc:6A7F8945D9F14F5E|rigid:pDAsg3dJ2BzWP56eURgXagnzwS8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P47121	uniprotkb:P14136	intact:EBI-11532457|ensemblfungi:YJR071W	intact:EBI-744302|uniprotkb:Q53H98|uniprotkb:Q5D055|uniprotkb:Q6ZQS3|uniprotkb:Q7Z5J6|uniprotkb:Q7Z5J7|uniprotkb:Q96KS4|uniprotkb:Q96P18|uniprotkb:Q9UFD0|uniprotkb:B2RD44|uniprotkb:D3DX59|intact:EBI-3909365|uniprotkb:E9PAX3|ensembl:ENSP00000466598|uniprotkb:A7REI1	psi-mi:yj41_yeast(display_long)|uniprotkb:J1818(orf name)|uniprotkb:YJR071W(locus name)	psi-mi:gfap_human(display_long)|uniprotkb:GFAP(gene name)|psi-mi:GFAP(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11532459|imex:IM-24995-1058	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003832|ensemblfungi:YJR071W(gene)|ensemblfungi:YJR071W_mRNA(transcript)|sgd:YJR071W(identity)	refseq:NP_001124491.1|refseq:NP_001229305.1|refseq:NP_002046.1|ensembl:ENSG00000131095(gene)|ensembl:ENST00000588735(transcript)|go:"GO:0005178"(integrin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0009611"(response to wounding)|go:"GO:0010467"(gene expression)|go:"GO:0010625"(positive regulation of Schwann cell proliferation)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0014002"(astrocyte development)|go:"GO:0019900"(kinase binding)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0031102"(neuron projection regeneration)|go:"GO:0042802"(identical protein binding)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0044297"(cell body)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0051580"(regulation of neurotransmitter uptake)|go:"GO:0060020"(Bergmann glial cell differentiation)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0070779"(D-aspartate import across plasma membrane)|go:"GO:0097450"(astrocyte end-foot)|go:"GO:0098574"(cytoplasmic side of lysosomal membrane)|go:"GO:1904714"(regulation of chaperone-mediated autophagy)|interpro:IPR006821(Intermediate filament, DNA-binding region)|interpro:IPR018039|interpro:IPR027701|interpro:IPR039008|mint:P14136|rcsb pdb:6A9P|reactome:R-HSA-1251985|reactome:R-HSA-9613829|entrezgene/locuslink:2670(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/03/16	rogid:5IM71Y0Z5uWfytzg3rXeNU+zCIs559292	rogid:Pz4JW0WjMjBYILTDSX9jUmMqWhg9606	intact-crc:FFD2B77663424336|rigid:sThOr4vPEYaMHtC3NM5RUYom1j8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P47121	uniprotkb:P19012	intact:EBI-11532457|ensemblfungi:YJR071W	intact:EBI-739566|uniprotkb:Q53XV8|uniprotkb:Q9BUG4|uniprotkb:B3KQY1|uniprotkb:B3KRA2|uniprotkb:E0CX14|ensembl:ENSP00000254043|ensembl:ENSP00000377546	psi-mi:yj41_yeast(display_long)|uniprotkb:J1818(orf name)|uniprotkb:YJR071W(locus name)	psi-mi:k1c15_human(display_long)|uniprotkb:KRT15(gene name)|psi-mi:KRT15(display_short)|uniprotkb:KRTB(gene name synonym)|uniprotkb:Cytokeratin-15(gene name synonym)|uniprotkb:Keratin-15(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11532468|imex:IM-24995-1059	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003832|ensemblfungi:YJR071W(gene)|ensemblfungi:YJR071W_mRNA(transcript)|sgd:YJR071W(identity)	refseq:NP_002266.2|ensembl:ENSG00000171346(gene)|ensembl:ENST00000254043(transcript)|ensembl:ENST00000393976(transcript)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0008544"(epidermis development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097110"(scaffold protein binding)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR039008|mint:P19012|reactome:R-HSA-6805567|reactome:R-HSA-6809371|entrezgene/locuslink:3866(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/03/16	rogid:5IM71Y0Z5uWfytzg3rXeNU+zCIs559292	rogid:WrZQBYQvrWcfrR5ojWXrXp6spPE9606	intact-crc:BAEEC488BD4F8307|rigid:N7wAs75Cz60FYATyk61zyKc9+i0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96BA8	uniprotkb:P47124	intact:EBI-6942903|ensembl:ENSP00000481956|intact:MINT-268046|intact:MINT-8162577|uniprotkb:Q8N2D5|uniprotkb:Q96CP0	intact:EBI-8430|uniprotkb:E9P8X6|uniprotkb:D6VWP5|ensemblfungi:YJR075W	psi-mi:cr3l1_human(display_long)|uniprotkb:CREB3L1(gene name)|psi-mi:CREB3L1(display_short)|uniprotkb:OASIS(gene name synonym)|uniprotkb:PSEC0238(orf name)|uniprotkb:Old astrocyte specifically-induced substance(gene name synonym)	psi-mi:hoc1_yeast(display_long)|uniprotkb:HOC1(gene name)|psi-mi:HOC1(display_short)|uniprotkb:YJR075W(locus name)|uniprotkb:J1830(orf name)|uniprotkb:Mannan polymerase II complex HOC1 subunit(gene name synonym)|uniprotkb:M-Pol II subunit Hoc1p(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11532477|imex:IM-24995-1060	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157613(gene)|ensembl:ENST00000621158(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0070278"(extracellular matrix constituent secretion)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029805|mint:Q96BA8|reactome:R-HSA-8874211|refseq:NP_443086.1|entrezgene/locuslink:90993(identity)	sgd:S000003836|refseq:NP_012609.3|dip:DIP-918N|ensemblfungi:YJR075W(gene)|ensemblfungi:YJR075W_mRNA(transcript)|go:"GO:0000009"(alpha-1,6-mannosyltransferase activity)|go:"GO:0000032"(cell wall mannoprotein biosynthetic process)|go:"GO:0000136"(mannan polymerase complex)|go:"GO:0006080"(substituted mannan metabolic process)|go:"GO:0006491"(N-glycan processing)|interpro:IPR007577(Glycosyltransferase sugar-binding region containing DXD motif)|interpro:IPR029044|interpro:IPR039367|sgd:YJR075W(identity)	-	comment:mint|function:"Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE"	crc64:8BF77385510DE6B0	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:sMWUFmBeBBCO+T0Y2CuB/un1lBg9606	rogid:wfRzXnEiSgEJNFaUo37t6GRAYmY559292	intact-crc:6CEADB6998270881|rigid:6zFeAftRsIp5f5CsGelMlyM8KK0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8NHQ1	uniprotkb:P47130	intact:EBI-739624|ensembl:ENSP00000264982|ensembl:ENSP00000419231|uniprotkb:Q96B31|uniprotkb:Q9H2C3|uniprotkb:Q9H2Z1|uniprotkb:Q9H940|uniprotkb:D3DNE9|uniprotkb:B7Z5I8|uniprotkb:B7Z7E8|uniprotkb:F5GZX8	intact:EBI-763|uniprotkb:D6VWQ3|ensemblfungi:YJR084W	psi-mi:cep70_human(display_long)|uniprotkb:CEP70(gene name)|psi-mi:CEP70(display_short)|uniprotkb:BITE(gene name synonym)|uniprotkb:p10-binding protein(gene name synonym)	psi-mi:csn12_yeast(display_long)|uniprotkb:J1860(orf name)|uniprotkb:YJR084W(locus name)|uniprotkb:CSN12(gene name)|psi-mi:CSN12(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11532486|imex:IM-24995-1061	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114107(gene)|ensembl:ENST00000264982(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|interpro:IPR019734|interpro:IPR037692|mint:Q8NHQ1|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|ensembl:ENST00000484888(transcript)|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_077817.2|refseq:XP_016862764.1|refseq:NP_001275893.1|refseq:NP_001275894.1|refseq:NP_001275895.1|refseq:NP_001275896.1|refseq:NP_001307527.1|refseq:NP_001307529.1|entrezgene/locuslink:80321(identity)	refseq:NP_012617.1|sgd:S000003844|dip:DIP-6710N|mint:P47130|ensemblfungi:YJR084W(gene)|ensemblfungi:YJR084W_mRNA(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000754"(adaptation of signaling pathway by response to pheromone involved in conjugation with cellular fusion)|go:"GO:0000973"(posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0070390"(transcription export complex 2)|go:"GO:0071033"|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR036388|sgd:YJR084W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:S4yveQWcvdVtAUX65gqrJ5Dv0Mc9606	rogid:3mwOzmQkVCLzVvabW1WAjChHkg8559292	intact-crc:CDAE278DE9C58DDF|rigid:vZhLFDSYHDxeoMiZ7ixn8lWni20	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P47133	uniprotkb:P50222	intact:EBI-25568|uniprotkb:D6VWQ6|uniprotkb:Q66R61|ensemblfungi:YJR088C	intact:EBI-748397|uniprotkb:O75263|ensembl:ENSP00000262041|uniprotkb:Q9UPL6|uniprotkb:B2R8I7|intact:EBI-10172134|intact:EBI-11522964|intact:EBI-11750003|intact:EBI-12702266|uniprotkb:A4D127	psi-mi:emc2_yeast(display_long)|uniprotkb:EMC2(gene name)|psi-mi:EMC2(display_short)|uniprotkb:J1875(orf name)|uniprotkb:YJR088C(locus name)	psi-mi:meox2_human(display_long)|uniprotkb:Mesenchyme homeobox 2(gene name synonym)|uniprotkb:Growth arrest-specific homeobox(gene name synonym)|uniprotkb:MEOX2(gene name)|psi-mi:MEOX2(display_short)|uniprotkb:GAX(gene name synonym)|uniprotkb:MOX2(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11532495|imex:IM-24995-1062	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012621.1|sgd:S000003848|dip:DIP-7609N|ensemblfungi:YJR088C(gene)|ensemblfungi:YJR088C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0072546"(EMC complex)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR039856|rcsb pdb:6WB9|rcsb pdb:7KRA|rcsb pdb:7KTX|sgd:YJR088C(identity)	ensembl:ENSG00000106511(gene)|ensembl:ENST00000262041(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0001757"(somite specification)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007275"(multicellular organism development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008015"(blood circulation)|go:"GO:0016607"(nuclear speck)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060173"(limb development)|go:"GO:0061053"(somite development)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR042634|refseq:NP_005915.2|entrezgene/locuslink:4223(identity)	-	crc64:157A03E75FB9E72A	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2017/05/26	rogid:p1r7k3QtfCRO93w9iBzh6wYGL9Q559292	rogid:fMv0ruKikzQ3MC0PBvJ3pOAjW+U9606	intact-crc:82607F27F469D17B|rigid:Nl+LiBV9j9ECxZnmhoSaGE9xlXc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P47133	uniprotkb:Q8N6Y0	intact:EBI-25568|uniprotkb:D6VWQ6|uniprotkb:Q66R61|ensemblfungi:YJR088C	intact:EBI-739895|uniprotkb:Q8NBX7|uniprotkb:Q96KH3|uniprotkb:Q9BYI8|uniprotkb:A8K7L6|uniprotkb:B2RCR9|ensembl:ENSP00000252597	psi-mi:emc2_yeast(display_long)|uniprotkb:EMC2(gene name)|psi-mi:EMC2(display_short)|uniprotkb:J1875(orf name)|uniprotkb:YJR088C(locus name)	psi-mi:usbp1_human(display_long)|uniprotkb:USHBP1(gene name)|psi-mi:USHBP1(display_short)|uniprotkb:MCC-2(gene name synonym)|uniprotkb:AIE-75-binding protein(gene name synonym)|uniprotkb:AIEBP(gene name synonym)|uniprotkb:MCC2(gene name synonym)|uniprotkb:Mutated in colon cancer protein 2(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11532504|imex:IM-24995-1063	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012621.1|sgd:S000003848|dip:DIP-7609N|ensemblfungi:YJR088C(gene)|ensemblfungi:YJR088C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0072546"(EMC complex)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR039856|rcsb pdb:6WB9|rcsb pdb:7KRA|rcsb pdb:7KTX|sgd:YJR088C(identity)	refseq:NP_001284632.1|refseq:NP_114147.2|refseq:NP_001308346.1|ensembl:ENSG00000130307(gene)|ensembl:ENST00000252597(transcript)|go:"GO:0030165"(PDZ domain binding)|interpro:IPR019536|interpro:IPR040171|entrezgene/locuslink:83878(identity)	-	crc64:157A03E75FB9E72A	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:p1r7k3QtfCRO93w9iBzh6wYGL9Q559292	rogid:vY1qx73Ju/z7WDu6k1kd10ZDVRo9606	intact-crc:0E124ED3816FC29C|rigid:FYmRLOyXsbEWBakVmoQuJEvha18	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O00444	uniprotkb:P47141	intact:EBI-746202|uniprotkb:Q8IYF0|uniprotkb:Q96Q95|uniprotkb:B2RAL0|uniprotkb:B7Z837|uniprotkb:B7Z8G7|uniprotkb:Q9UD84|uniprotkb:Q9UDE2|ensembl:ENSP00000270861	intact:EBI-25588|uniprotkb:D6VWS0|ensemblfungi:YJR101W	psi-mi:plk4_human(display_long)|uniprotkb:Polo-like kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase Sak(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 18(gene name synonym)|uniprotkb:PLK4(gene name)|psi-mi:PLK4(display_short)|uniprotkb:SAK(gene name synonym)|uniprotkb:STK18(gene name synonym)	psi-mi:rt26_yeast(display_long)|uniprotkb:RSM26(gene name)|psi-mi:RSM26(display_short)|uniprotkb:Mitochondrial small ribosomal subunit protein mS42(gene name synonym)|uniprotkb:J1952(orf name)|uniprotkb:YJR101W(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11532513|imex:IM-24995-1064	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001177728.1|refseq:NP_001177730.1|refseq:NP_055079.3|dip:DIP-34467N|rcsb pdb:5LHZ|rcsb pdb:6N45|rcsb pdb:6N46|rcsb pdb:6W38|rcsb pdb:6W3I|rcsb pdb:6W3J|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|rcsb pdb:5LHY|reactome:R-HSA-5620912|reactome:R-HSA-8854518|ensembl:ENSG00000142731(gene)|ensembl:ENST00000270861(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0001741"(XY body)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007099"(centriole replication)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0046601"(positive regulation of centriole replication)|go:"GO:0060271"(cilium assembly)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0098535"(de novo centriole assembly involved in multi-ciliated epithelial cell differentiation)|go:"GO:0098536"(deuterosome)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033696|interpro:IPR033698|interpro:IPR033699|interpro:IPR033700|mint:O00444|rcsb pdb:2N19|rcsb pdb:3COK|rcsb pdb:4JXF|rcsb pdb:4N7V|rcsb pdb:4N7Z|rcsb pdb:4N9J|rcsb pdb:4YUR|rcsb pdb:4YYP|entrezgene/locuslink:10733(identity)	refseq:NP_012635.1|sgd:S000003862|mint:P47141|dip:DIP-6695N|ensemblfungi:YJR101W(gene)|ensemblfungi:YJR101W_mRNA(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0004784"(superoxide dismutase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0032543"(mitochondrial translation)|go:"GO:0046872"(metal ion binding)|interpro:IPR019832|interpro:IPR036314|interpro:IPR036324|rcsb pdb:5MRC|rcsb pdb:5MRE|rcsb pdb:5MRF|sgd:YJR101W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:xqjVEnoGXDk/+2AzLRAkyPK80OI9606	rogid:SlIhesyBGcjVv9vDlv43gnSLZ2o559292	intact-crc:722AA87DC35644FF|rigid:YSl4RqDpH160BRgvgBss6G3F8xE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96H20	uniprotkb:P47142	intact:EBI-747719|uniprotkb:Q8IXY3|uniprotkb:Q9UN50|ensembl:ENSP00000421380	intact:EBI-25595|uniprotkb:D6VWS1|ensemblfungi:YJR102C	psi-mi:snf8_human(display_long)|uniprotkb:ELL-associated protein of 30 kDa(gene name synonym)|uniprotkb:SNF8(gene name)|psi-mi:SNF8(display_short)|uniprotkb:EAP30(gene name synonym)|uniprotkb:ESCRT-II complex subunit VPS22(gene name synonym)	psi-mi:vps25_yeast(display_long)|uniprotkb:YJR102C(locus name)|uniprotkb:J1957(orf name)|uniprotkb:VPS25(gene name)|psi-mi:VPS25(display_short)|uniprotkb:VPT25(gene name synonym)|uniprotkb:ESCRT-II complex subunit VPS25(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11532522|imex:IM-24995-1065	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009172.2|refseq:NP_001304121.1|refseq:NP_001304122.1|refseq:NP_001304123.1|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010008"(endosome membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0016247"(channel regulator activity)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043328"(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055037"(recycling endosome)|go:"GO:0061635"(regulation of protein complex stability)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071985"(multivesicular body sorting pathway)|go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:1903772"(regulation of viral budding via host ESCRT complex)|interpro:IPR016689(ESCRT-2 complex, Snf8)|interpro:IPR036388|interpro:IPR036390|interpro:IPR040608|mint:Q96H20|rcsb pdb:2ZME|rcsb pdb:3CUQ|reactome:R-HSA-917729|reactome:R-HSA-9610379|ensembl:ENSG00000159210(gene)|ensembl:ENST00000502492(transcript)|go:"GO:0000814"(ESCRT II complex)|entrezgene/locuslink:11267(identity)	refseq:NP_012636.1|sgd:S000003863|mint:P47142|dip:DIP-4446N|ensemblfungi:YJR102C(gene)|ensemblfungi:YJR102C_mRNA(transcript)|go:"GO:0000433"(carbon catabolite repression of transcription from RNA polymerase II promoter by glucose)|go:"GO:0000814"(ESCRT II complex)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043328"(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:1904669"(ATP export)|interpro:IPR008570(ESCRT-II complex, vps25 subunit)|interpro:IPR014041(ESCRT-II complex, vps25 subunit, N-terminal winged helix)|interpro:IPR036388|interpro:IPR036390|rcsb pdb:1U5T|rcsb pdb:1W7P|rcsb pdb:1XB4|reactome:R-SCE-917729|sgd:YJR102C(identity)	-	-	crc64:6A4545A8BC772CA2	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:FyjlBpOt9okBFV8Z+g8YLUeyCm49606	rogid:LlNZVpWKYsWsgu0FcP2sL10lYHc559292	intact-crc:CFC494C08A71427F|rigid:FYnf8xbP9QsNSNXgRnwRbzuWSOE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:A0A024R4Q5	uniprotkb:P47167	intact:EBI-11527449	intact:EBI-25691|uniprotkb:D6VWV3|ensemblfungi:YJR135C	psi-mi:a0a024r4q5_human(display_long)|uniprotkb:hCG_20946(orf name)|uniprotkb:TFPT(gene name)|psi-mi:TFPT(display_short)	psi-mi:cenpk_yeast(display_long)|uniprotkb:YJR135C(locus name)|uniprotkb:J2122(orf name)|uniprotkb:MCM22(gene name)|psi-mi:MCM22(display_short)|uniprotkb:Minichromosome maintenance protein 22(gene name synonym)|uniprotkb:CENP-K homolog(gene name synonym)|uniprotkb:Constitutive centromere-associated network protein MCM22(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11532561|imex:IM-24995-1069	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_037474.1|interpro:IPR033555|go:"GO:0005654"(nucleoplasm)|go:"GO:0006915"(apoptotic process)|entrezgene/locuslink:29844(identity)	sgd:S000003896|refseq:NP_012669.1|mint:P47167|dip:DIP-1431N|ensemblfungi:YJR135C(gene)|ensemblfungi:YJR135C_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0007059"(chromosome segregation)|go:"GO:0034087"(establishment of mitotic sister chromatid cohesion)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|rcsb pdb:6OUA|rcsb pdb:6QLD|rcsb pdb:6QLE|rcsb pdb:6WUC|rcsb pdb:6YPC|rcsb pdb:7L7Q|sgd:YJR135C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:juI/3gZemjc0hnXDJ9J+bIQ9pBw9606	rogid:LcYkK++8vfcxUaACTUgOFftDVyc559292	intact-crc:A093C1574D6335DF|rigid:ZTXIMsSGw1x74kumZO63mW+N3Co	false	sufficient binding region:10-253	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P47162	uniprotkb:Q15038	intact:EBI-11532550|uniprotkb:A0A1S0T089|ensemblfungi:YJR128W	intact:EBI-724310|ensembl:ENSP00000394699|uniprotkb:E9PB45|uniprotkb:A8K254|uniprotkb:B4DDT5|uniprotkb:C9JA96|uniprotkb:C9JP84|uniprotkb:B4E1G3|uniprotkb:F8VU62	psi-mi:yj98_yeast(display_long)|uniprotkb:J2059(orf name)|uniprotkb:YJR128W(locus name)	psi-mi:dazp2_human(display_long)|uniprotkb:Deleted in azoospermia-associated protein 2(gene name synonym)|uniprotkb:DAZAP2(gene name)|psi-mi:DAZAP2(display_short)|uniprotkb:KIAA0058(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11532552|imex:IM-24995-1068	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003889|ensemblfungi:YJR128W(gene)|ensemblfungi:YJR128W_mRNA(transcript)|sgd:YJR128W(identity)	ensembl:ENSG00000183283(gene)|ensembl:ENST00000412716(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0016607"(nuclear speck)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0050699"(WW domain binding)|interpro:IPR022730|mint:Q15038|refseq:NP_001129736.1|refseq:NP_055579.1|ensembl:ENSP00000394699|ensembl:ENST00000425012|ensembl:ENSP00000408251|ensembl:ENST00000439799|ensembl:ENSP00000398804|ensembl:ENST00000449723|ensembl:ENSP00000412812|ensembl:ENST00000549555|ensembl:ENSP00000448051|ensembl:ENST00000549732|ensembl:ENSP00000446554|refseq:NP_001129741.1|refseq:NP_001129739.1|refseq:NP_001129740.1|refseq:NP_001129738.1|entrezgene/locuslink:9802(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/03/16	rogid:utEI06SlO/HvqiPnUtJUHtxxOBo559292	rogid:ASRqCZBG4q1U/y95PUSMKsgfm/g9606	intact-crc:136A4429CB46E5DC|rigid:wfMFpeoVlRmYhu/ezZM1vkzm8ek	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P19012	uniprotkb:P48232	intact:EBI-739566|uniprotkb:Q53XV8|uniprotkb:Q9BUG4|uniprotkb:B3KQY1|uniprotkb:B3KRA2|uniprotkb:E0CX14|ensembl:ENSP00000254043|ensembl:ENSP00000377546	intact:EBI-28775|uniprotkb:D6W193|ensemblfungi:YNL086W	psi-mi:k1c15_human(display_long)|uniprotkb:KRT15(gene name)|psi-mi:KRT15(display_short)|uniprotkb:KRTB(gene name synonym)|uniprotkb:Cytokeratin-15(gene name synonym)|uniprotkb:Keratin-15(gene name synonym)	psi-mi:snapn_yeast(display_long)|uniprotkb:YNL086W(locus name)|uniprotkb:N2254(orf name)|uniprotkb:SNN1(gene name)|psi-mi:SNN1(display_short)|uniprotkb:SNAPIN-like protein 1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11532591|imex:IM-24995-1072	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002266.2|ensembl:ENSG00000171346(gene)|ensembl:ENST00000254043(transcript)|ensembl:ENST00000393976(transcript)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0008544"(epidermis development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097110"(scaffold protein binding)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR039008|mint:P19012|reactome:R-HSA-6805567|reactome:R-HSA-6809371|entrezgene/locuslink:3866(identity)	refseq:NP_014313.1|sgd:S000005030|dip:DIP-1188N|mint:P48232|ensemblfungi:YNL086W(gene)|ensemblfungi:YNL086W_mRNA(transcript)|go:"GO:0005768"(endosome)|go:"GO:0007032"(endosome organization)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0032880"(regulation of protein localization)|sgd:YNL086W(identity)	-	-	crc64:33200D2F0F729DA1	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:WrZQBYQvrWcfrR5ojWXrXp6spPE9606	rogid:XCPaHuGC9oKD/3W0gY5ZY8jKtFs559292	intact-crc:F32AEC619D30AC54|rigid:hL9Sjv5M1RtaCp4N61Zl1BEcb5g	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P08727	uniprotkb:P48232	intact:EBI-742756|uniprotkb:Q5XG83|uniprotkb:Q6NW33|uniprotkb:Q7L5M9|uniprotkb:Q96A53|uniprotkb:Q96FV1|uniprotkb:Q9BYF9|uniprotkb:Q9P1Y4|uniprotkb:B2R874|ensembl:ENSP00000355124	intact:EBI-28775|uniprotkb:D6W193|ensemblfungi:YNL086W	psi-mi:k1c19_human(display_long)|uniprotkb:Cytokeratin-19(gene name synonym)|uniprotkb:Keratin-19(gene name synonym)|uniprotkb:KRT19(gene name)|psi-mi:KRT19(display_short)	psi-mi:snapn_yeast(display_long)|uniprotkb:YNL086W(locus name)|uniprotkb:N2254(orf name)|uniprotkb:SNN1(gene name)|psi-mi:SNN1(display_short)|uniprotkb:SNAPIN-like protein 1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11532581|imex:IM-24995-1071	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002267.2|ensembl:ENSG00000171345(gene)|ensembl:ENST00000361566(transcript)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0030018"(Z disc)|go:"GO:0042383"(sarcolemma)|go:"GO:0043034"(costamere)|go:"GO:0043627"(response to estrogen)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0060706"(cell differentiation involved in embryonic placenta development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071944"(cell periphery)|go:"GO:1990357"(terminal web)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR039008|mint:P08727|reactome:R-HSA-6805567|reactome:R-HSA-6809371|dip:DIP-35655N|entrezgene/locuslink:3880(identity)	refseq:NP_014313.1|sgd:S000005030|dip:DIP-1188N|mint:P48232|ensemblfungi:YNL086W(gene)|ensemblfungi:YNL086W_mRNA(transcript)|go:"GO:0005768"(endosome)|go:"GO:0007032"(endosome organization)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0032880"(regulation of protein localization)|sgd:YNL086W(identity)	-	-	crc64:33200D2F0F729DA1	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:fqsG2nghpcmTtI39LiYVLNYuFIA9606	rogid:XCPaHuGC9oKD/3W0gY5ZY8jKtFs559292	intact-crc:D72C2064F406FBD5|rigid:CwltGDU4oRqebkTElyclVSZmLGU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96BA8	uniprotkb:P47190	intact:EBI-6942903|ensembl:ENSP00000481956|intact:MINT-268046|intact:MINT-8162577|uniprotkb:Q8N2D5|uniprotkb:Q96CP0	intact:EBI-13579|uniprotkb:D6W319|ensemblfungi:YOR321W	psi-mi:cr3l1_human(display_long)|uniprotkb:CREB3L1(gene name)|psi-mi:CREB3L1(display_short)|uniprotkb:OASIS(gene name synonym)|uniprotkb:PSEC0238(orf name)|uniprotkb:Old astrocyte specifically-induced substance(gene name synonym)	psi-mi:pmt3_yeast(display_long)|uniprotkb:PMT3(gene name)|psi-mi:PMT3(display_short)|uniprotkb:O6148(orf name)|uniprotkb:YOR321W(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11532572|imex:IM-24995-1070	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157613(gene)|ensembl:ENST00000621158(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0070278"(extracellular matrix constituent secretion)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029805|mint:Q96BA8|reactome:R-HSA-8874211|refseq:NP_443086.1|entrezgene/locuslink:90993(identity)	refseq:NP_014966.1|sgd:S000005848|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:0097582"(dolichyl-phosphate-mannose-protein mannosyltransferase Pmt1p-Pmt2p dimer complex)|go:"GO:0097583"(dolichyl-phosphate-mannose-protein mannosyltransferase Pmt1p-Pmt3p dimer complex)|go:"GO:0097585"(dolichyl-phosphate-mannose-protein mannosyltransferase Pmt5p-Pmt3p dimer complex)|interpro:IPR003342(Glycosyl transferase, family 39)|interpro:IPR016093(MIR motif)|interpro:IPR027005|interpro:IPR032421|ensemblfungi:YOR321W(gene)|ensemblfungi:YOR321W_mRNA(transcript)|go:"GO:0004169"(dolichyl-phosphate-mannose-protein mannosyltransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006493"(protein O-linked glycosylation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035269"(protein O-linked mannosylation)|interpro:IPR036300|rcsb pdb:6ZQQ|dip:DIP-5158N|sgd:YOR321W(identity)	-	comment:mint|function:"Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE"	crc64:F076473B41EB6CBA	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:sMWUFmBeBBCO+T0Y2CuB/un1lBg9606	rogid:JsPUkzaK8sNWifvo5m9Ixhly2P8559292	intact-crc:C4A2302D85589FC4|rigid:xKfN74/ZVuRBhxSOHz5/z8hDN4A	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96BA8	uniprotkb:P47155	intact:EBI-6942903|ensembl:ENSP00000481956|intact:MINT-268046|intact:MINT-8162577|uniprotkb:Q8N2D5|uniprotkb:Q96CP0	intact:EBI-2051644|uniprotkb:D6VWT7|ensemblfungi:YJR118C	psi-mi:cr3l1_human(display_long)|uniprotkb:CREB3L1(gene name)|psi-mi:CREB3L1(display_short)|uniprotkb:OASIS(gene name synonym)|uniprotkb:PSEC0238(orf name)|uniprotkb:Old astrocyte specifically-induced substance(gene name synonym)	psi-mi:ilm1_yeast(display_long)|uniprotkb:Increased loss of mitochondrial DNA protein 1(gene name synonym)|uniprotkb:J2033(orf name)|uniprotkb:ILM1(gene name)|psi-mi:ILM1(display_short)|uniprotkb:YJR118C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11532540|imex:IM-24995-1067	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157613(gene)|ensembl:ENST00000621158(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0070278"(extracellular matrix constituent secretion)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029805|mint:Q96BA8|reactome:R-HSA-8874211|refseq:NP_443086.1|entrezgene/locuslink:90993(identity)	sgd:S000003879|interpro:IPR018815|refseq:NP_012652.3|mint:P47155|ensemblfungi:YJR118C(gene)|ensemblfungi:YJR118C_mRNA(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|sgd:YJR118C(identity)	-	comment:mint|function:"Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE"	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:sMWUFmBeBBCO+T0Y2CuB/un1lBg9606	rogid:BrQhbXGvUjNG6Bt5c0J7T8qzMeI559292	intact-crc:DD571432D3037C7D|rigid:lCg7wDQ2zuSIP1rO0i23xqrT9Zg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96H20-2	uniprotkb:P47142	intact:EBI-11121416|ensembl:ENSP00000290330	intact:EBI-25595|uniprotkb:D6VWS1|ensemblfungi:YJR102C	psi-mi:q96h20-2(display_long)|uniprotkb:SNF8(gene name)|psi-mi:SNF8(display_short)|uniprotkb:EAP30(gene name synonym)|uniprotkb:ELL-associated protein of 30 kDa(gene name synonym)|uniprotkb:ESCRT-II complex subunit VPS22(gene name synonym)	psi-mi:vps25_yeast(display_long)|uniprotkb:YJR102C(locus name)|uniprotkb:J1957(orf name)|uniprotkb:VPS25(gene name)|psi-mi:VPS25(display_short)|uniprotkb:VPT25(gene name synonym)|uniprotkb:ESCRT-II complex subunit VPS25(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11532531|imex:IM-24995-1066	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-747719(isoform-parent)|ensembl:ENSG00000159210(gene)|ensembl:ENST00000290330(transcript)|entrezgene/locuslink:11267(identity)	refseq:NP_012636.1|sgd:S000003863|mint:P47142|dip:DIP-4446N|ensemblfungi:YJR102C(gene)|ensemblfungi:YJR102C_mRNA(transcript)|go:"GO:0000433"(carbon catabolite repression of transcription from RNA polymerase II promoter by glucose)|go:"GO:0000814"(ESCRT II complex)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043328"(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:1904669"(ATP export)|interpro:IPR008570(ESCRT-II complex, vps25 subunit)|interpro:IPR014041(ESCRT-II complex, vps25 subunit, N-terminal winged helix)|interpro:IPR036388|interpro:IPR036390|rcsb pdb:1U5T|rcsb pdb:1W7P|rcsb pdb:1XB4|reactome:R-SCE-917729|sgd:YJR102C(identity)	-	isoform-comment:No experimental confirmation available.	crc64:6A4545A8BC772CA2	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Q8Kde7wzzgiTELEbfVpV36PVV5E9606	rogid:LlNZVpWKYsWsgu0FcP2sL10lYHc559292	intact-crc:B5E07DA84CC9DEAC|rigid:B0FGWfS0RZ18UHY60iRrpmjLYVQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48362	uniprotkb:Q969G2	intact:EBI-8304|uniprotkb:D6VUX0|ensemblfungi:YGR187C	intact:EBI-2865388|uniprotkb:Q8NHM1|uniprotkb:Q969W2|uniprotkb:Q8TCJ1|uniprotkb:Q8NHE0|uniprotkb:Q8WWX2|ensembl:ENSP00000263726	psi-mi:hgh1_yeast(display_long)|uniprotkb:HGH1(gene name)|psi-mi:HGH1(display_short)|uniprotkb:HMG1/2 protein homolog(gene name synonym)|uniprotkb:G7538(orf name)|uniprotkb:YGR187C(locus name)	psi-mi:lhx4_human(display_long)|uniprotkb:LHX4(gene name)|psi-mi:LHX4(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11532672|imex:IM-24995-1081	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003419|refseq:NP_011703.3|mint:P48362|dip:DIP-4721N|ensemblfungi:YGR187C(gene)|ensemblfungi:YGR187C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0061770"(translation elongation factor binding)|interpro:IPR007205(Protein of unknown function DUF383)|interpro:IPR007206(Protein of unknown function DUF384)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR039717|rcsb pdb:6HB1|rcsb pdb:6HB2|rcsb pdb:6HB3|sgd:YGR187C(identity)	refseq:NP_203129.1|dip:DIP-29454N|ensembl:ENSG00000121454(gene)|ensembl:ENST00000263726(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001890"(placenta development)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0021526"(medial motor column neuron differentiation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|mint:Q969G2|rcsb pdb:5HOD|reactome:R-HSA-9010553|entrezgene/locuslink:89884(identity)	-	crc64:24D4EFAEBD5D7A48	crc64:6499F38E78B79FD1	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:YQkKPiBqhycG0Z+2lxERBLVdy1w559292	rogid:dCB3WgIBMdi0nNvaCFaioh+F9sw9606	intact-crc:6B73E5C0845B04AA|rigid:+aolQ+4ablvd2k8Qys4GsTOkhZg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9NPJ6	uniprotkb:P48232	intact:EBI-394607|uniprotkb:Q9BS95|uniprotkb:Q9NYR5|uniprotkb:Q53GB4|uniprotkb:Q53H68|uniprotkb:Q5T912|uniprotkb:Q6FHC4|uniprotkb:Q6IA79|uniprotkb:B4DX67|ensembl:ENSP00000258648	intact:EBI-28775|uniprotkb:D6W193|ensemblfungi:YNL086W	psi-mi:med4_human(display_long)|uniprotkb:HSPC126(orf name)|uniprotkb:DRIP36(gene name synonym)|uniprotkb:MED4(gene name)|psi-mi:MED4(display_short)|uniprotkb:ARC36(gene name synonym)|uniprotkb:Mediator complex subunit 4(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex 36 kDa component(gene name synonym)|uniprotkb:Activator-recruited cofactor 36 kDa component(gene name synonym)|uniprotkb:TRAP/SMCC/PC2 subunit p36 subunit(gene name synonym)|uniprotkb:VDRIP(gene name synonym)	psi-mi:snapn_yeast(display_long)|uniprotkb:YNL086W(locus name)|uniprotkb:N2254(orf name)|uniprotkb:SNN1(gene name)|psi-mi:SNN1(display_short)|uniprotkb:SNAPIN-like protein 1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11532663|imex:IM-24995-1080	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001257558.1|refseq:NP_054885.1|ensembl:ENSG00000136146(gene)|ensembl:ENST00000258648(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0070847"(core mediator complex)|interpro:IPR019258|mint:Q9NPJ6|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|entrezgene/locuslink:29079(identity)	refseq:NP_014313.1|sgd:S000005030|dip:DIP-1188N|mint:P48232|ensemblfungi:YNL086W(gene)|ensemblfungi:YNL086W_mRNA(transcript)|go:"GO:0005768"(endosome)|go:"GO:0007032"(endosome organization)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0032880"(regulation of protein localization)|sgd:YNL086W(identity)	-	-	crc64:33200D2F0F729DA1	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Bept2Oec50gruA9e4pf+eEUiANM9606	rogid:XCPaHuGC9oKD/3W0gY5ZY8jKtFs559292	intact-crc:3D4B1EBE7E42ABE7|rigid:ZUrZqOehAmrIHlIcTMuqZVSdGYo	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48232	uniprotkb:Q9BUW7	intact:EBI-28775|uniprotkb:D6W193|ensemblfungi:YNL086W	intact:EBI-752084|uniprotkb:Q9Y3F7|uniprotkb:Q5SYV8|ensembl:ENSP00000362085	psi-mi:snapn_yeast(display_long)|uniprotkb:YNL086W(locus name)|uniprotkb:N2254(orf name)|uniprotkb:SNN1(gene name)|psi-mi:SNN1(display_short)|uniprotkb:SNAPIN-like protein 1(gene name synonym)	psi-mi:bbln_human(display_long)|uniprotkb:BBLN(gene name)|psi-mi:BBLN(display_short)|uniprotkb:C9orf16(gene name synonym)|uniprotkb:UPF0184 protein C9orf16(gene name synonym)|uniprotkb:EST00098(orf name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11532654|imex:IM-24995-1079	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014313.1|sgd:S000005030|dip:DIP-1188N|mint:P48232|ensemblfungi:YNL086W(gene)|ensemblfungi:YNL086W_mRNA(transcript)|go:"GO:0005768"(endosome)|go:"GO:0007032"(endosome organization)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0032880"(regulation of protein localization)|sgd:YNL086W(identity)	refseq:NP_077017.1|dip:DIP-29481N|ensembl:ENSG00000171159(gene)|ensembl:ENST00000372994(transcript)|interpro:IPR005374(Protein of unknown function UPF0184)|entrezgene/locuslink:79095(identity)	-	crc64:33200D2F0F729DA1	crc64:EBE1D0AFAAD6DABB	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:XCPaHuGC9oKD/3W0gY5ZY8jKtFs559292	rogid:O4VcHghk63gMrjyh5XKmkZovFZ49606	intact-crc:9DEA1BA3C6DC3B14|rigid:iljLLz95tUWEiho68kbnmxPDoTE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96L14	uniprotkb:P48232	intact:EBI-743488	intact:EBI-28775|uniprotkb:D6W193|ensemblfungi:YNL086W	psi-mi:c170l_human(display_long)|uniprotkb:KIAA0470L(gene name synonym)|uniprotkb:CEP170P1(gene name)|psi-mi:CEP170P1(display_short)|uniprotkb:CEP170L(gene name synonym)|uniprotkb:CEP170 pseudogene 1(gene name synonym)	psi-mi:snapn_yeast(display_long)|uniprotkb:YNL086W(locus name)|uniprotkb:N2254(orf name)|uniprotkb:SNN1(gene name)|psi-mi:SNN1(display_short)|uniprotkb:SNAPIN-like protein 1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11532645|imex:IM-24995-1078	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR026644|interpro:IPR029300|go:"GO:0042802"(identical protein binding)|entrezgene/locuslink:645455(identity)	refseq:NP_014313.1|sgd:S000005030|dip:DIP-1188N|mint:P48232|ensemblfungi:YNL086W(gene)|ensemblfungi:YNL086W_mRNA(transcript)|go:"GO:0005768"(endosome)|go:"GO:0007032"(endosome organization)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0032880"(regulation of protein localization)|sgd:YNL086W(identity)	-	-	crc64:33200D2F0F729DA1	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Z/Rium0Kwj3ZUHa4WE5PPksPXdg9606	rogid:XCPaHuGC9oKD/3W0gY5ZY8jKtFs559292	intact-crc:7BC1C3D6FE955C65|rigid:Nt9hHYoJV/gor2whzS37apTB0CM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96EV8	uniprotkb:P48232	intact:EBI-465804|uniprotkb:Q5THY3|uniprotkb:Q5THY4|uniprotkb:Q96NV2|intact:EBI-28986386|ensembl:ENSP00000341680|uniprotkb:Q9H0U2|uniprotkb:Q9H3J5|uniprotkb:A8K3V3	intact:EBI-28775|uniprotkb:D6W193|ensemblfungi:YNL086W	psi-mi:dtbp1_human(display_long)|uniprotkb:My031(orf name)|uniprotkb:DTNBP1(gene name)|psi-mi:DTNBP1(display_short)|uniprotkb:Dystrobrevin-binding protein 1(gene name synonym)|uniprotkb:Hermansky-Pudlak syndrome 7 protein(gene name synonym)|uniprotkb:Dysbindin-1(gene name synonym)|uniprotkb:BLOC1S8(gene name synonym)|uniprotkb:Biogenesis of lysosome-related organelles complex 1 subunit 8(gene name synonym)	psi-mi:snapn_yeast(display_long)|uniprotkb:YNL086W(locus name)|uniprotkb:N2254(orf name)|uniprotkb:SNN1(gene name)|psi-mi:SNN1(display_short)|uniprotkb:SNAPIN-like protein 1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11532636|imex:IM-24995-1077	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000047579(gene)|ensembl:ENST00000344537(transcript)|go:"GO:0001956"(positive regulation of neurotransmitter secretion)|go:"GO:0005634"(nucleus)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007596"(blood coagulation)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014059"(regulation of dopamine secretion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016528"(sarcoplasm)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0030496"(midbody)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032438"(melanosome organization)|go:"GO:0033162"(melanosome membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0043005"(neuron projection)|go:"GO:0043197"(dendritic spine)|go:"GO:0005737"(cytoplasm)|go:"GO:0043506"(regulation of JUN kinase activity)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0060155"(platelet dense granule organization)|go:"GO:0060159"(regulation of dopamine receptor signaling pathway)|go:"GO:0071901"(negative regulation of protein serine/threonine kinase activity)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR007531(Dysbindin)|reactome:R-HSA-432722|go:"GO:0048490"(anterograde synaptic vesicle transport)|refseq:NP_115498.2|refseq:NP_898861.1|refseq:NP_001258597.1|refseq:NP_001258598.1|ensembl:ENST00000338950|ensembl:ENSP00000344718|ensembl:ENSP00000341680|refseq:NP_001258596.1|entrezgene/locuslink:84062(identity)	refseq:NP_014313.1|sgd:S000005030|dip:DIP-1188N|mint:P48232|ensemblfungi:YNL086W(gene)|ensemblfungi:YNL086W_mRNA(transcript)|go:"GO:0005768"(endosome)|go:"GO:0007032"(endosome organization)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0032880"(regulation of protein localization)|sgd:YNL086W(identity)	-	-	crc64:33200D2F0F729DA1	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:PBwxp1vobm9l5yGoqev97lzkMHg9606	rogid:XCPaHuGC9oKD/3W0gY5ZY8jKtFs559292	intact-crc:544951C20D355E1C|rigid:G5QXP+d4EP28p40fQo/bbxOmhiQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48232	uniprotkb:Q96BD8	intact:EBI-28775|uniprotkb:D6W193|ensemblfungi:YNL086W	intact:EBI-741854|uniprotkb:B2R9Y6|uniprotkb:B4E0P4|ensembl:ENSP00000285116|ensembl:ENSP00000381470|ensembl:ENSP00000458992|ensembl:ENSP00000478259	psi-mi:snapn_yeast(display_long)|uniprotkb:YNL086W(locus name)|uniprotkb:N2254(orf name)|uniprotkb:SNN1(gene name)|psi-mi:SNN1(display_short)|uniprotkb:SNAPIN-like protein 1(gene name synonym)	psi-mi:ska1_human(display_long)|uniprotkb:SKA1(gene name)|psi-mi:SKA1(display_short)|uniprotkb:C18orf24(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11532627|imex:IM-24995-1076	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014313.1|sgd:S000005030|dip:DIP-1188N|mint:P48232|ensemblfungi:YNL086W(gene)|ensemblfungi:YNL086W_mRNA(transcript)|go:"GO:0005768"(endosome)|go:"GO:0007032"(endosome organization)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0032880"(regulation of protein localization)|sgd:YNL086W(identity)	refseq:NP_001034624.1|refseq:NP_659497.1|ensembl:ENSG00000154839(gene)|ensembl:ENSG00000262634(gene)|ensembl:ENST00000285116(transcript)|ensembl:ENST00000398452(transcript)|ensembl:ENST00000571751(transcript)|ensembl:ENST00000616604(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000940"(outer kinetochore)|go:"GO:0005829"(cytosol)|go:"GO:0005876"(spindle microtubule)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008017"(microtubule binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0031110"(regulation of microtubule polymerization or depolymerization)|go:"GO:0051301"(cell division)|go:"GO:0072686"(mitotic spindle)|interpro:IPR009829(Protein of unknown function DUF1395)|interpro:IPR042031|mint:Q96BD8|rcsb pdb:4AJ5|rcsb pdb:4C9Y|rcsb pdb:4CA0|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|entrezgene/locuslink:220134(identity)	-	crc64:33200D2F0F729DA1	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:XCPaHuGC9oKD/3W0gY5ZY8jKtFs559292	rogid:Z7y57MeLsUJK0R9JNqHJNBbKr/89606	intact-crc:7A2F56637B69E182|rigid:UB/Bin/IhLlBAU8regFNV3ErgzA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8NA61-2	uniprotkb:P48232	intact:EBI-11524851|ensembl:ENSP00000368249|ensembl:ENSP00000480148	intact:EBI-28775|uniprotkb:D6W193|ensemblfungi:YNL086W	psi-mi:q8na61-2(display_long)|uniprotkb:CBY2(gene name)|psi-mi:CBY2(display_short)|uniprotkb:SPERT(gene name synonym)|uniprotkb:Spermatid-associated protein(gene name synonym)	psi-mi:snapn_yeast(display_long)|uniprotkb:YNL086W(locus name)|uniprotkb:N2254(orf name)|uniprotkb:SNN1(gene name)|psi-mi:SNN1(display_short)|uniprotkb:SNAPIN-like protein 1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11532618|imex:IM-24995-1075	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-741724(isoform-parent)|ensembl:ENSG00000174015(gene)|ensembl:ENST00000378966(transcript)|ensembl:ENST00000610924(transcript)|uniprotkb:Q8NA61-2(isoform-parent)|entrezgene/locuslink:220082(identity)	refseq:NP_014313.1|sgd:S000005030|dip:DIP-1188N|mint:P48232|ensemblfungi:YNL086W(gene)|ensemblfungi:YNL086W_mRNA(transcript)|go:"GO:0005768"(endosome)|go:"GO:0007032"(endosome organization)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0032880"(regulation of protein localization)|sgd:YNL086W(identity)	-	-	crc64:33200D2F0F729DA1	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:SogYcXGGMYRYzB9xKC5o0pEtsDs9606	rogid:XCPaHuGC9oKD/3W0gY5ZY8jKtFs559292	intact-crc:51BAE614D1EDBFE3|rigid:92+xr8GGy4qpJmxzQhTfRNYxDWE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8N6Y0	uniprotkb:P48232	intact:EBI-739895|uniprotkb:Q8NBX7|uniprotkb:Q96KH3|uniprotkb:Q9BYI8|uniprotkb:A8K7L6|uniprotkb:B2RCR9|ensembl:ENSP00000252597	intact:EBI-28775|uniprotkb:D6W193|ensemblfungi:YNL086W	psi-mi:usbp1_human(display_long)|uniprotkb:USHBP1(gene name)|psi-mi:USHBP1(display_short)|uniprotkb:MCC-2(gene name synonym)|uniprotkb:AIE-75-binding protein(gene name synonym)|uniprotkb:AIEBP(gene name synonym)|uniprotkb:MCC2(gene name synonym)|uniprotkb:Mutated in colon cancer protein 2(gene name synonym)	psi-mi:snapn_yeast(display_long)|uniprotkb:YNL086W(locus name)|uniprotkb:N2254(orf name)|uniprotkb:SNN1(gene name)|psi-mi:SNN1(display_short)|uniprotkb:SNAPIN-like protein 1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11532609|imex:IM-24995-1074	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001284632.1|refseq:NP_114147.2|refseq:NP_001308346.1|ensembl:ENSG00000130307(gene)|ensembl:ENST00000252597(transcript)|go:"GO:0030165"(PDZ domain binding)|interpro:IPR019536|interpro:IPR040171|entrezgene/locuslink:83878(identity)	refseq:NP_014313.1|sgd:S000005030|dip:DIP-1188N|mint:P48232|ensemblfungi:YNL086W(gene)|ensemblfungi:YNL086W_mRNA(transcript)|go:"GO:0005768"(endosome)|go:"GO:0007032"(endosome organization)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0032880"(regulation of protein localization)|sgd:YNL086W(identity)	-	-	crc64:33200D2F0F729DA1	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:vY1qx73Ju/z7WDu6k1kd10ZDVRo9606	rogid:XCPaHuGC9oKD/3W0gY5ZY8jKtFs559292	intact-crc:815152F1AD859EA5|rigid:DY0xKzsTS1LyJKp5ymhNiy00JT8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48232	uniprotkb:P37198	intact:EBI-28775|uniprotkb:D6W193|ensemblfungi:YNL086W	intact:EBI-347978|intact:EBI-28983799|ensembl:ENSP00000305503|ensembl:ENSP00000407331|ensembl:ENSP00000471191|ensembl:ENSP00000473192|uniprotkb:Q6GTM2|uniprotkb:Q503A4|uniprotkb:Q96C43|uniprotkb:Q9NSL1|uniprotkb:B3KWU5	psi-mi:snapn_yeast(display_long)|uniprotkb:YNL086W(locus name)|uniprotkb:N2254(orf name)|uniprotkb:SNN1(gene name)|psi-mi:SNN1(display_short)|uniprotkb:SNAPIN-like protein 1(gene name synonym)	psi-mi:nup62_human(display_long)|uniprotkb:NUP62(gene name)|psi-mi:NUP62(display_short)|uniprotkb:62 kDa nucleoporin(gene name synonym)|uniprotkb:Nucleoporin Nup62(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11532600|imex:IM-24995-1073	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014313.1|sgd:S000005030|dip:DIP-1188N|mint:P48232|ensemblfungi:YNL086W(gene)|ensemblfungi:YNL086W_mRNA(transcript)|go:"GO:0005768"(endosome)|go:"GO:0007032"(endosome organization)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0032880"(regulation of protein localization)|sgd:YNL086W(identity)	refseq:NP_714941.1|ensembl:ENSG00000213024(gene)|ensembl:ENST00000352066(transcript)|ensembl:ENST00000422090(transcript)|ensembl:ENST00000596217(transcript)|ensembl:ENST00000597029(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005642"(annulate lamellae)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007100"(mitotic centrosome separation)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007569"(cell aging)|go:"GO:0008219"(cell death)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0003682"(chromatin binding)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0019894"(kinesin binding)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042306"(regulation of protein import into nucleus)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043069"(negative regulation of programmed cell death)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045742"(positive regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046578"(regulation of Ras protein signal transduction)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0046601"(positive regulation of centriole replication)|go:"GO:0051028"(mRNA transport)|go:"GO:0051425"(PTB domain binding)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0072686"(mitotic spindle)|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|go:"GO:0090543"(Flemming body)|go:"GO:0098534"(centriole assembly)|go:"GO:1903438"(positive regulation of mitotic cytokinetic process)|go:"GO:1904781"(positive regulation of protein localization to centrosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR007758(Nucleoporin, Nsp1-like, C-terminal)|interpro:IPR026010|interpro:IPR033072|mint:P37198|rcsb pdb:2H4D|rcsb pdb:5IJN|rcsb pdb:5IJO|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|refseq:NP_714940.1|refseq:NP_001180286.1|refseq:NP_036478.2|refseq:NP_057637.2|ensembl:ENSP00000305503|ensembl:ENSP00000407331|ensembl:ENSP00000471191|ensembl:ENSP00000473192|dip:DIP-29749N|entrezgene/locuslink:23636(identity)	-	crc64:33200D2F0F729DA1	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:XCPaHuGC9oKD/3W0gY5ZY8jKtFs559292	rogid:v7mvKvTtVEnLMwcpUZIcdAzge009606	intact-crc:F7A44AE2F1FC1325|rigid:rpFh96J0kfVyT0N8FIrOoIJ+kmM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P13196	uniprotkb:P48837	intact:EBI-3905054|ensembl:ENSP00000309259|ensembl:ENSP00000378416|ensembl:ENSP00000417719|ensembl:ENSP00000418779	intact:EBI-12324|ensemblfungi:YGR119C|uniprotkb:D6VUQ0	psi-mi:hem1_human(display_long)|uniprotkb:ALAS1(gene name)|psi-mi:ALAS1(display_short)|uniprotkb:ALAS3(gene name synonym)|uniprotkb:ALASH(gene name synonym)|uniprotkb:5-aminolevulinic acid synthase 1(gene name synonym)|uniprotkb:Delta-ALA synthase 1(gene name synonym)|uniprotkb:Delta-aminolevulinate synthase 1(gene name synonym)|uniprotkb:OK/SW-cl.121(orf name)	psi-mi:nup57_yeast(display_long)|uniprotkb:NUP57(gene name)|psi-mi:NUP57(display_short)|uniprotkb:YGR119C(locus name)|uniprotkb:G6320(orf name)|uniprotkb:Nuclear pore protein NUP57(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11532730|imex:IM-24995-1087	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001291372.1|refseq:NP_001291373.1|refseq:NP_000679.1|refseq:NP_954635.1|go:"GO:0006783"(heme biosynthetic process)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0042541"(hemoglobin biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0048821"(erythrocyte development)|ensembl:ENSG00000023330(gene)|ensembl:ENST00000310271(transcript)|ensembl:ENST00000394965(transcript)|ensembl:ENST00000469224(transcript)|ensembl:ENST00000484952(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0003870"(5-aminolevulinate synthase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|interpro:IPR001917(Aminotransferase, class-II, pyridoxal-phosphate binding site)|interpro:IPR004839(Aminotransferase, class I and II)|interpro:IPR010961(Tetrapyrrole biosynthesis, 5-aminolevulinic acid synthase)|interpro:IPR015118(5-aminolevulinate synthase presequence)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|mint:P13196|reactome:R-HSA-189451|reactome:R-HSA-1989781|reactome:R-HSA-2151201|go:"GO:0006782"(protoporphyrinogen IX biosynthetic process)|entrezgene/locuslink:211(identity)	ensemblfungi:YGR119C(gene)|ensemblfungi:YGR119C_mRNA(transcript)|go:"GO:0005643"(nuclear pore)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036228"(protein localization to nuclear inner membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0051028"(mRNA transport)|interpro:IPR024864|interpro:IPR025574|interpro:IPR025712|refseq:NP_011634.1|sgd:S000003351|mint:P48837|dip:DIP-866N|sgd:YGR119C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:HFjJ6zrRF9UYD7LMB6A3CcxcS7c9606	rogid:ultDTflWHx7n/y2FrlWFf+lBKmw559292	intact-crc:70D8B34B7B44757A|rigid:55dkBZdItqxpdefbuIni1NTAFrc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q7Z6G3-2	uniprotkb:P48837	intact:EBI-10172876|ensembl:ENSP00000457354|intact:EBI-14062040	intact:EBI-12324|ensemblfungi:YGR119C|uniprotkb:D6VUQ0	psi-mi:q7z6g3-2(display_long)|uniprotkb:EFCBP2(gene name synonym)|uniprotkb:Neuronal calcium-binding protein 2(gene name synonym)|uniprotkb:Synaptotagmin-interacting protein 2(gene name synonym)|uniprotkb:NECAB2(gene name)|psi-mi:NECAB2(display_short)	psi-mi:nup57_yeast(display_long)|uniprotkb:NUP57(gene name)|psi-mi:NUP57(display_short)|uniprotkb:YGR119C(locus name)|uniprotkb:G6320(orf name)|uniprotkb:Nuclear pore protein NUP57(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11532719|imex:IM-24995-1086	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000103154(gene)|ensembl:ENST00000565691(transcript)|uniprotkb:Q7Z6G3-2(isoform-parent)|intact:EBI-950070(isoform-parent)|entrezgene/locuslink:54550(identity)	ensemblfungi:YGR119C(gene)|ensemblfungi:YGR119C_mRNA(transcript)|go:"GO:0005643"(nuclear pore)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036228"(protein localization to nuclear inner membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0051028"(mRNA transport)|interpro:IPR024864|interpro:IPR025574|interpro:IPR025712|refseq:NP_011634.1|sgd:S000003351|mint:P48837|dip:DIP-866N|sgd:YGR119C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:4S7oIx6h+mKzV3EPxqcfMNqaNko9606	rogid:ultDTflWHx7n/y2FrlWFf+lBKmw559292	intact-crc:F26A8E9683B89CF4|rigid:2L/mQtHxIaS+bEFnqSRPYF5iGLE	false	sufficient binding region:65-303	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q08379	uniprotkb:P48837	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	intact:EBI-12324|ensemblfungi:YGR119C|uniprotkb:D6VUQ0	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:nup57_yeast(display_long)|uniprotkb:NUP57(gene name)|psi-mi:NUP57(display_short)|uniprotkb:YGR119C(locus name)|uniprotkb:G6320(orf name)|uniprotkb:Nuclear pore protein NUP57(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11532708|imex:IM-24995-1085	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N|entrezgene/locuslink:2801(identity)	ensemblfungi:YGR119C(gene)|ensemblfungi:YGR119C_mRNA(transcript)|go:"GO:0005643"(nuclear pore)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036228"(protein localization to nuclear inner membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0051028"(mRNA transport)|interpro:IPR024864|interpro:IPR025574|interpro:IPR025712|refseq:NP_011634.1|sgd:S000003351|mint:P48837|dip:DIP-866N|sgd:YGR119C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2017/05/26	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	rogid:ultDTflWHx7n/y2FrlWFf+lBKmw559292	intact-crc:8C2E6ACE37DBD47D|rigid:lWusjqueKh0Hnk8R2KrjGBwfThU	false	sufficient binding region:383-1002	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q99598	uniprotkb:P48606	intact:EBI-742638|intact:EBI-1050136|uniprotkb:B1APC6|refseq:NP_005990|dip:DIP-29463N	intact:EBI-18991|uniprotkb:D6W2W5|ensemblfungi:YOR265W	psi-mi:tsnax_human(display_long)|uniprotkb:Translin-associated factor X(gene name synonym)|uniprotkb:TSNAX(gene name)|psi-mi:TSNAX(display_short)|uniprotkb:TRAX(gene name synonym)	psi-mi:tbca_yeast(display_long)|uniprotkb:YOR265W(locus name)|uniprotkb:RBL2(gene name)|psi-mi:RBL2(display_short)|uniprotkb:Tubulin-folding cofactor A(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11532699|imex:IM-24995-1084	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005634"(nucleus)|go:"GO:0008565"(obsolete protein transporter activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0007275"(multicellular organism development)|go:"GO:0007283"(spermatogenesis)|refseq:NP_005990.1|interpro:IPR002848(Translin)|interpro:IPR016068(Translin, N-terminal)|rcsb pdb:3PJA|rcsb pdb:3QB5|ensembl:ENST00000366639|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0031047"(gene silencing by RNA)|reactome:R-HSA-426486|go:"GO:0030422"(production of siRNA involved in RNA interference)|interpro:IPR036081|go:"GO:0003677"(DNA binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0046872"(metal ion binding)|go:"GO:0005829"(cytosol)|ensembl:ENSG00000116918|ensembl:ENSP00000355599|go:"GO:0005654"(nucleoplasm)|go:"GO:0003723"(RNA binding)|dip:DIP-29463N|mint:MINT-1347706|go:"GO:0044822"|interpro:IPR016069(Translin, C-terminal)|go:"GO:0031687"(A2A adenosine receptor binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0003697"(single-stranded DNA binding)|entrezgene/locuslink:7257(identity)	ensemblfungi:YOR265W(gene)|ensemblfungi:YOR265W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:0007023"(post-chaperonin tubulin folding pathway)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0015631"(tubulin binding)|go:"GO:0048487"(beta-tubulin binding)|interpro:IPR004226(Tubulin binding cofactor A)|interpro:IPR036126|rcsb pdb:1QSD|refseq:NP_014908.1|sgd:S000005791|dip:DIP-4101N|mint:P48606|sgd:YOR265W(identity)	-	crc64:D38B0DD96B50C0B9|no-uniprot-update:|caution:"The protein could not be merged with EBI-12908040 because of some conflicts with the protein sequence (features which cannot be shifted)."	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:TaNIxjLHGusdq32WbdJ21DG9yBQ9606	rogid:Qbjv1Un+CKyQZ+gTbJl7ETlkc9o559292	intact-crc:0F57F50F746BF131|rigid:SmxS0R0ePAiBfY3hx6PXEYderCQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48510	uniprotkb:O14641	intact:EBI-6174|uniprotkb:D6W0A3|ensemblfungi:YMR276W	intact:EBI-740850|ensembl:ENSP00000005340|uniprotkb:Q53XM0|uniprotkb:D3DTN3	psi-mi:dsk2_yeast(display_long)|uniprotkb:DSK2(gene name)|psi-mi:DSK2(display_short)|uniprotkb:SHE4(gene name synonym)|uniprotkb:YMR276W(locus name)|uniprotkb:YM8021.02(orf name)	psi-mi:dvl2_human(display_long)|uniprotkb:DSH homolog 2(gene name synonym)|uniprotkb:DVL2(gene name)|psi-mi:DVL2(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11532690|imex:IM-24995-1083	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014003.1|sgd:S000004889|dip:DIP-4398N|mint:P48510|ensemblfungi:YMR276W(gene)|ensemblfungi:YMR276W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030474"(spindle pole body duplication)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0072665"(protein localization to vacuole)|interpro:IPR000626(Ubiquitin)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR019954|interpro:IPR029071|rcsb pdb:1WR1|rcsb pdb:2BWB|rcsb pdb:2BWE|rcsb pdb:2BWF|rcsb pdb:3M63|rcsb pdb:4UN2|reactome:R-SCE-8856825|sgd:YMR276W(identity)	refseq:NP_004413.1|ensembl:ENSG00000004975(gene)|ensembl:ENST00000005340(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005109"(frizzled binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0007507"(heart development)|go:"GO:0016235"(aggresome)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044340"(canonical Wnt signaling pathway involved in regulation of cell proliferation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0150012"(positive regulation of neuron projection arborization)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008341(Dishevelled-2 region)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:O14641|rcsb pdb:2REY|rcsb pdb:3CBX|rcsb pdb:3CBY|rcsb pdb:3CBZ|rcsb pdb:3CC0|rcsb pdb:4WIP|rcsb pdb:5LNP|rcsb pdb:5SUY|rcsb pdb:5SUZ|rcsb pdb:6IW3|rcsb pdb:6JCK|reactome:R-HSA-201681|reactome:R-HSA-201688|reactome:R-HSA-2028269|reactome:R-HSA-4086400|reactome:R-HSA-4608870|reactome:R-HSA-4641258|reactome:R-HSA-4641262|reactome:R-HSA-5099900|reactome:R-HSA-5368598|reactome:R-HSA-5663220|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9673324|ensembl:ENSP00000005340|dip:DIP-34433N|entrezgene/locuslink:1856(identity)	-	crc64:3F8691BB95E46569	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:1hHbfo970BiDc/ZuAO8Jc6V9vEI559292	rogid:2Vdc8oRnT4Mz/j+EXQXrL3AszOc9606	intact-crc:D08909F24F544352|rigid:OFBwQNwhklTLKJu+V2vrPLrktfw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48362	uniprotkb:Q9UHV2	intact:EBI-8304|uniprotkb:D6VUX0|ensemblfungi:YGR187C	intact:EBI-748601|uniprotkb:Q9BUE7|ensembl:ENSP00000350633	psi-mi:hgh1_yeast(display_long)|uniprotkb:HGH1(gene name)|psi-mi:HGH1(display_short)|uniprotkb:HMG1/2 protein homolog(gene name synonym)|uniprotkb:G7538(orf name)|uniprotkb:YGR187C(locus name)	psi-mi:srtd1_human(display_long)|uniprotkb:Transcriptional regulator interacting with the PHD-bromodomain 1(gene name synonym)|uniprotkb:CDK4-binding protein p34SEI1(gene name synonym)|uniprotkb:SERTAD1(gene name)|psi-mi:SERTAD1(display_short)|uniprotkb:SEI1(gene name synonym)|uniprotkb:TRIPBR1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11532681|imex:IM-24995-1082	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003419|refseq:NP_011703.3|mint:P48362|dip:DIP-4721N|ensemblfungi:YGR187C(gene)|ensemblfungi:YGR187C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0061770"(translation elongation factor binding)|interpro:IPR007205(Protein of unknown function DUF383)|interpro:IPR007206(Protein of unknown function DUF384)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR039717|rcsb pdb:6HB1|rcsb pdb:6HB2|rcsb pdb:6HB3|sgd:YGR187C(identity)	refseq:NP_037508.2|ensembl:ENSG00000197019(gene)|ensembl:ENST00000357949(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048096"|interpro:IPR009263(SERTA)|mint:Q9UHV2|entrezgene/locuslink:29950(identity)	-	crc64:24D4EFAEBD5D7A48	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:YQkKPiBqhycG0Z+2lxERBLVdy1w559292	rogid:40dvjniwxY/UQiyoVREicctpWe09606	intact-crc:F5FEA220449928AE|rigid:kPL182n1L1WDQj5e2ABipEAp9dM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q53EZ4	uniprotkb:P49089	intact:EBI-747776|uniprotkb:Q32WF5|uniprotkb:Q3MV20|uniprotkb:Q5VY28|uniprotkb:Q6N034|ensembl:ENSP00000360540|uniprotkb:Q96H32|uniprotkb:Q9NVS7|uniprotkb:B2RDG8|intact:EBI-10173536|uniprotkb:D3DR37|intact:EBI-28973801	intact:EBI-3043|uniprotkb:D6W4E2|ensemblfungi:YPR145W	psi-mi:cep55_human(display_long)|uniprotkb:Up-regulated in colon cancer 6(gene name synonym)|uniprotkb:CEP55(gene name)|psi-mi:CEP55(display_short)|uniprotkb:URCC6(gene name synonym)|uniprotkb:C10orf3(gene name synonym)	psi-mi:asns1_yeast(display_long)|uniprotkb:ASN1(gene name)|psi-mi:ASN1(display_short)|uniprotkb:YPR145W(locus name)|uniprotkb:P9659.3(orf name)|uniprotkb:Glutamine-dependent asparagine synthetase 1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11532802|imex:IM-24995-1095	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001120654.1|refseq:NP_060601.3|ensembl:ENSG00000138180(gene)|ensembl:ENST00000371485(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0014066"(regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0030496"(midbody)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042802"(identical protein binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0061952"(midbody abscission)|go:"GO:0090543"(Flemming body)|go:"GO:1904888"(cranial skeletal system development)|interpro:IPR022008|interpro:IPR038926|mint:Q53EZ4|rcsb pdb:3E1R|rcsb pdb:3WUT|rcsb pdb:3WUU|rcsb pdb:3WUV|go:"GO:0005814"(centriole)|ensembl:ENSP00000360540|dip:DIP-44581N|entrezgene/locuslink:55165(identity)	refseq:NP_015471.1|sgd:S000006349|dip:DIP-3810N|reactome:R-SCE-8963693|ensemblfungi:YPR145W(gene)|ensemblfungi:YPR145W_mRNA(transcript)|go:"GO:0004066"("asparagine synthase (glutamine-hydrolyzing) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006529"(asparagine biosynthetic process)|go:"GO:0006541"(glutamine metabolic process)|go:"GO:0070981"(L-asparagine biosynthetic process)|interpro:IPR001962(Asparagine synthase)|interpro:IPR006426(Asparagine synthase, glutamine-hydrolyzing)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR017932|interpro:IPR029055|interpro:IPR033738|sgd:YPR145W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:tuo36vVb8ZgPDR81YjZFNEg559w9606	rogid:jel8vvbk1/PZHmUs57fDe2ybZ3Q559292	intact-crc:9EFEB02AF6FF373B|rigid:VoacHHA6wqVGluBP+KxT9eZssmY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49017	uniprotkb:Q6RW13-2	intact:EBI-4937|ensemblfungi:YML110C|uniprotkb:D6W0H4	intact:EBI-11522760|ensembl:ENSP00000365816	psi-mi:coq5_yeast(display_long)|uniprotkb:COQ5(gene name)|psi-mi:COQ5(display_short)|uniprotkb:DBI56(gene name synonym)|uniprotkb:YML110C(locus name)|uniprotkb:YM8339.09C(orf name)|uniprotkb:Ubiquinone biosynthesis methyltransferase COQ5(gene name synonym)|uniprotkb:2-hexaprenyl-6-methoxy-1,4-benzoquinol methyltransferase(gene name synonym)	psi-mi:q6rw13-2(display_long)|uniprotkb:AGTRAP(gene name)|psi-mi:AGTRAP(display_short)|uniprotkb:AT1 receptor-associated protein(gene name synonym)|uniprotkb:ATRAP(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11532793|imex:IM-24995-1094	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YML110C(gene)|ensemblfungi:YML110C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006744"(ubiquinone biosynthetic process)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0009060"(aerobic respiration)|go:"GO:0031314"(extrinsic component of mitochondrial inner membrane)|go:"GO:0032259"(methylation)|go:"GO:0043333"(2-octaprenyl-6-methoxy-1,4-benzoquinone methylase activity)|go:"GO:0043334"(2-hexaprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity)|interpro:IPR004033(UbiE/COQ5 methyltransferase)|interpro:IPR023576|interpro:IPR029063|rcsb pdb:4OBW|rcsb pdb:4OBX|refseq:NP_013597.1|sgd:S000004578|dip:DIP-1639N|sgd:YML110C(identity)	ensembl:ENSG00000177674(gene)|ensembl:ENST00000376629(transcript)|intact:EBI-741181(isoform-parent)|uniprotkb:Q6RW13-2(isoform-parent)|entrezgene/locuslink:57085(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:rgHxCUvCLn3xoq9Jv4EMhFupCmI559292	rogid:PNzVis/8puQZBJ562gCqZKc078s9606	intact-crc:C063614F41E6D7D0|rigid:2l2i9Qj0Zo0jzW6ribbZQlzU90w	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48837	uniprotkb:Q9NPJ6	intact:EBI-12324|ensemblfungi:YGR119C|uniprotkb:D6VUQ0	intact:EBI-394607|uniprotkb:Q9BS95|uniprotkb:Q9NYR5|uniprotkb:Q53GB4|uniprotkb:Q53H68|uniprotkb:Q5T912|uniprotkb:Q6FHC4|uniprotkb:Q6IA79|uniprotkb:B4DX67|ensembl:ENSP00000258648	psi-mi:nup57_yeast(display_long)|uniprotkb:NUP57(gene name)|psi-mi:NUP57(display_short)|uniprotkb:YGR119C(locus name)|uniprotkb:G6320(orf name)|uniprotkb:Nuclear pore protein NUP57(gene name synonym)	psi-mi:med4_human(display_long)|uniprotkb:HSPC126(orf name)|uniprotkb:DRIP36(gene name synonym)|uniprotkb:MED4(gene name)|psi-mi:MED4(display_short)|uniprotkb:ARC36(gene name synonym)|uniprotkb:Mediator complex subunit 4(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex 36 kDa component(gene name synonym)|uniprotkb:Activator-recruited cofactor 36 kDa component(gene name synonym)|uniprotkb:TRAP/SMCC/PC2 subunit p36 subunit(gene name synonym)|uniprotkb:VDRIP(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11532784|imex:IM-24995-1093	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YGR119C(gene)|ensemblfungi:YGR119C_mRNA(transcript)|go:"GO:0005643"(nuclear pore)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036228"(protein localization to nuclear inner membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0051028"(mRNA transport)|interpro:IPR024864|interpro:IPR025574|interpro:IPR025712|refseq:NP_011634.1|sgd:S000003351|mint:P48837|dip:DIP-866N|sgd:YGR119C(identity)	refseq:NP_001257558.1|refseq:NP_054885.1|ensembl:ENSG00000136146(gene)|ensembl:ENST00000258648(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0070847"(core mediator complex)|interpro:IPR019258|mint:Q9NPJ6|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|entrezgene/locuslink:29079(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:ultDTflWHx7n/y2FrlWFf+lBKmw559292	rogid:Bept2Oec50gruA9e4pf+eEUiANM9606	intact-crc:BEC484071615611F|rigid:E4yC3H7ZNEmr16/ErOuydE6jpDM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48837	uniprotkb:Q8N6Y0	intact:EBI-12324|ensemblfungi:YGR119C|uniprotkb:D6VUQ0	intact:EBI-739895|uniprotkb:Q8NBX7|uniprotkb:Q96KH3|uniprotkb:Q9BYI8|uniprotkb:A8K7L6|uniprotkb:B2RCR9|ensembl:ENSP00000252597	psi-mi:nup57_yeast(display_long)|uniprotkb:NUP57(gene name)|psi-mi:NUP57(display_short)|uniprotkb:YGR119C(locus name)|uniprotkb:G6320(orf name)|uniprotkb:Nuclear pore protein NUP57(gene name synonym)	psi-mi:usbp1_human(display_long)|uniprotkb:USHBP1(gene name)|psi-mi:USHBP1(display_short)|uniprotkb:MCC-2(gene name synonym)|uniprotkb:AIE-75-binding protein(gene name synonym)|uniprotkb:AIEBP(gene name synonym)|uniprotkb:MCC2(gene name synonym)|uniprotkb:Mutated in colon cancer protein 2(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11532775|imex:IM-24995-1092	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YGR119C(gene)|ensemblfungi:YGR119C_mRNA(transcript)|go:"GO:0005643"(nuclear pore)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036228"(protein localization to nuclear inner membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0051028"(mRNA transport)|interpro:IPR024864|interpro:IPR025574|interpro:IPR025712|refseq:NP_011634.1|sgd:S000003351|mint:P48837|dip:DIP-866N|sgd:YGR119C(identity)	refseq:NP_001284632.1|refseq:NP_114147.2|refseq:NP_001308346.1|ensembl:ENSG00000130307(gene)|ensembl:ENST00000252597(transcript)|go:"GO:0030165"(PDZ domain binding)|interpro:IPR019536|interpro:IPR040171|entrezgene/locuslink:83878(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:ultDTflWHx7n/y2FrlWFf+lBKmw559292	rogid:vY1qx73Ju/z7WDu6k1kd10ZDVRo9606	intact-crc:1F7213188570D5B8|rigid:JZ0fyuEAWv0wjPEHyZnsVFCGo1M	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48837	uniprotkb:Q5JR59-3	intact:EBI-12324|ensemblfungi:YGR119C|uniprotkb:D6VUQ0	intact:EBI-11522433|ensembl:ENSP00000370186	psi-mi:nup57_yeast(display_long)|uniprotkb:NUP57(gene name)|psi-mi:NUP57(display_short)|uniprotkb:YGR119C(locus name)|uniprotkb:G6320(orf name)|uniprotkb:Nuclear pore protein NUP57(gene name synonym)	psi-mi:q5jr59-3(display_long)|uniprotkb:MTUS2(gene name)|psi-mi:MTUS2(display_short)|uniprotkb:CAZIP(gene name synonym)|uniprotkb:Cardiac zipper protein(gene name synonym)|uniprotkb:KIAA0774(gene name synonym)|uniprotkb:Microtubule plus-end tracking protein TIP150(gene name synonym)|uniprotkb:TIP150(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11532766|imex:IM-24995-1091	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YGR119C(gene)|ensemblfungi:YGR119C_mRNA(transcript)|go:"GO:0005643"(nuclear pore)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036228"(protein localization to nuclear inner membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0051028"(mRNA transport)|interpro:IPR024864|interpro:IPR025574|interpro:IPR025712|refseq:NP_011634.1|sgd:S000003351|mint:P48837|dip:DIP-866N|sgd:YGR119C(identity)	ensembl:ENSG00000132938(gene)|ensembl:ENST00000380808(transcript)|intact:EBI-742948(isoform-parent)|uniprotkb:Q5JR59-3(isoform-parent)|entrezgene/locuslink:23281(identity)	-	-	isoform-comment:No experimental confirmation available.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:ultDTflWHx7n/y2FrlWFf+lBKmw559292	rogid:npId9tC7VoLN/jteoBiRbSYChPs9606	intact-crc:FB6817436E3AAD10|rigid:qPpBrX3s1J3WortwGo2VBLAlPzI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P43365	uniprotkb:P48837	intact:EBI-749530|uniprotkb:Q9NSD3|intact:EBI-10178394|uniprotkb:Q6FHH8|ensembl:ENSP00000350592|ensembl:ENSP00000377447|ensembl:ENSP00000377478	intact:EBI-12324|ensemblfungi:YGR119C|uniprotkb:D6VUQ0	psi-mi:magac_human(display_long)|uniprotkb:MAGE-12 antigen(gene name synonym)|uniprotkb:MAGE12F antigen(gene name synonym)|uniprotkb:Cancer/testis antigen 1.12(gene name synonym)|uniprotkb:MAGEA12(gene name)|psi-mi:MAGEA12(display_short)|uniprotkb:MAGE12(gene name synonym)	psi-mi:nup57_yeast(display_long)|uniprotkb:NUP57(gene name)|psi-mi:NUP57(display_short)|uniprotkb:YGR119C(locus name)|uniprotkb:G6320(orf name)|uniprotkb:Nuclear pore protein NUP57(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11532757|imex:IM-24995-1090	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001159858.1|refseq:NP_001159859.1|refseq:NP_005358.2|ensembl:ENSG00000213401(gene)|ensembl:ENST00000357916(transcript)|ensembl:ENST00000393869(transcript)|ensembl:ENST00000393900(transcript)|interpro:IPR002190(MAGE protein)|interpro:IPR021072|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|entrezgene/locuslink:4111(identity)	ensemblfungi:YGR119C(gene)|ensemblfungi:YGR119C_mRNA(transcript)|go:"GO:0005643"(nuclear pore)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036228"(protein localization to nuclear inner membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0051028"(mRNA transport)|interpro:IPR024864|interpro:IPR025574|interpro:IPR025712|refseq:NP_011634.1|sgd:S000003351|mint:P48837|dip:DIP-866N|sgd:YGR119C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:3/Jxz2VsFOb67RWqWj3xbTrw3s49606	rogid:ultDTflWHx7n/y2FrlWFf+lBKmw559292	intact-crc:412C9196FDEF5A77|rigid:RsooH0U2Ig2+KcoPlyd4E/fjdww	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48837	uniprotkb:P37198	intact:EBI-12324|ensemblfungi:YGR119C|uniprotkb:D6VUQ0	intact:EBI-347978|intact:EBI-28983799|ensembl:ENSP00000305503|ensembl:ENSP00000407331|ensembl:ENSP00000471191|ensembl:ENSP00000473192|uniprotkb:Q6GTM2|uniprotkb:Q503A4|uniprotkb:Q96C43|uniprotkb:Q9NSL1|uniprotkb:B3KWU5	psi-mi:nup57_yeast(display_long)|uniprotkb:NUP57(gene name)|psi-mi:NUP57(display_short)|uniprotkb:YGR119C(locus name)|uniprotkb:G6320(orf name)|uniprotkb:Nuclear pore protein NUP57(gene name synonym)	psi-mi:nup62_human(display_long)|uniprotkb:NUP62(gene name)|psi-mi:NUP62(display_short)|uniprotkb:62 kDa nucleoporin(gene name synonym)|uniprotkb:Nucleoporin Nup62(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11532748|imex:IM-24995-1089	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YGR119C(gene)|ensemblfungi:YGR119C_mRNA(transcript)|go:"GO:0005643"(nuclear pore)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036228"(protein localization to nuclear inner membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0051028"(mRNA transport)|interpro:IPR024864|interpro:IPR025574|interpro:IPR025712|refseq:NP_011634.1|sgd:S000003351|mint:P48837|dip:DIP-866N|sgd:YGR119C(identity)	refseq:NP_714941.1|ensembl:ENSG00000213024(gene)|ensembl:ENST00000352066(transcript)|ensembl:ENST00000422090(transcript)|ensembl:ENST00000596217(transcript)|ensembl:ENST00000597029(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005642"(annulate lamellae)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007100"(mitotic centrosome separation)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007569"(cell aging)|go:"GO:0008219"(cell death)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0003682"(chromatin binding)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0019894"(kinesin binding)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042306"(regulation of protein import into nucleus)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043069"(negative regulation of programmed cell death)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045742"(positive regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046578"(regulation of Ras protein signal transduction)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0046601"(positive regulation of centriole replication)|go:"GO:0051028"(mRNA transport)|go:"GO:0051425"(PTB domain binding)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0072686"(mitotic spindle)|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|go:"GO:0090543"(Flemming body)|go:"GO:0098534"(centriole assembly)|go:"GO:1903438"(positive regulation of mitotic cytokinetic process)|go:"GO:1904781"(positive regulation of protein localization to centrosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR007758(Nucleoporin, Nsp1-like, C-terminal)|interpro:IPR026010|interpro:IPR033072|mint:P37198|rcsb pdb:2H4D|rcsb pdb:5IJN|rcsb pdb:5IJO|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|refseq:NP_714940.1|refseq:NP_001180286.1|refseq:NP_036478.2|refseq:NP_057637.2|ensembl:ENSP00000305503|ensembl:ENSP00000407331|ensembl:ENSP00000471191|ensembl:ENSP00000473192|dip:DIP-29749N|entrezgene/locuslink:23636(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:ultDTflWHx7n/y2FrlWFf+lBKmw559292	rogid:v7mvKvTtVEnLMwcpUZIcdAzge009606	intact-crc:693CDB25D1275582|rigid:VKD44/kn1QgtmQW8jZJ27AtTQoA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48837	uniprotkb:P19012	intact:EBI-12324|ensemblfungi:YGR119C|uniprotkb:D6VUQ0	intact:EBI-739566|uniprotkb:Q53XV8|uniprotkb:Q9BUG4|uniprotkb:B3KQY1|uniprotkb:B3KRA2|uniprotkb:E0CX14|ensembl:ENSP00000254043|ensembl:ENSP00000377546	psi-mi:nup57_yeast(display_long)|uniprotkb:NUP57(gene name)|psi-mi:NUP57(display_short)|uniprotkb:YGR119C(locus name)|uniprotkb:G6320(orf name)|uniprotkb:Nuclear pore protein NUP57(gene name synonym)	psi-mi:k1c15_human(display_long)|uniprotkb:KRT15(gene name)|psi-mi:KRT15(display_short)|uniprotkb:KRTB(gene name synonym)|uniprotkb:Cytokeratin-15(gene name synonym)|uniprotkb:Keratin-15(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11532739|imex:IM-24995-1088	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YGR119C(gene)|ensemblfungi:YGR119C_mRNA(transcript)|go:"GO:0005643"(nuclear pore)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036228"(protein localization to nuclear inner membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0051028"(mRNA transport)|interpro:IPR024864|interpro:IPR025574|interpro:IPR025712|refseq:NP_011634.1|sgd:S000003351|mint:P48837|dip:DIP-866N|sgd:YGR119C(identity)	refseq:NP_002266.2|ensembl:ENSG00000171346(gene)|ensembl:ENST00000254043(transcript)|ensembl:ENST00000393976(transcript)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0008544"(epidermis development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097110"(scaffold protein binding)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR039008|mint:P19012|reactome:R-HSA-6805567|reactome:R-HSA-6809371|entrezgene/locuslink:3866(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:ultDTflWHx7n/y2FrlWFf+lBKmw559292	rogid:WrZQBYQvrWcfrR5ojWXrXp6spPE9606	intact-crc:DF331732793EF0E5|rigid:EWdg0xHy45l7+DZ8VcH2+fSyZqU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49955	uniprotkb:Q9UHX1-6	intact:EBI-664|uniprotkb:D6W0B5|ensemblfungi:YMR288W	intact:EBI-11085298|ensembl:ENSP00000431960	psi-mi:sf3b1_yeast(display_long)|uniprotkb:YMR288W(locus name)|uniprotkb:YM8021.14(orf name)|uniprotkb:HSH155(gene name)|psi-mi:HSH155(display_short)	psi-mi:q9uhx1-6(display_long)|uniprotkb:PUF60(gene name)|psi-mi:PUF60(display_short)|uniprotkb:"60 kDa poly(U)-binding-splicing factor"(gene name synonym)|uniprotkb:FIR(gene name synonym)|uniprotkb:FUSE-binding protein-interacting repressor(gene name synonym)|uniprotkb:ROBPI(gene name synonym)|uniprotkb:Ro-binding protein 1(gene name synonym)|uniprotkb:SIAHBP1(gene name synonym)|uniprotkb:Siah-binding protein 1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11532859|imex:IM-24995-1101	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014015.1|sgd:S000004901|dip:DIP-2628N|mint:P49955|ensemblfungi:YMR288W(gene)|ensemblfungi:YMR288W_mRNA(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005686"(U2 snRNP)|go:"GO:0071004"(U2-type prespliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR038737|rcsb pdb:5GM6|rcsb pdb:5LQW|rcsb pdb:5NRL|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:6G90|sgd:YMR288W(identity)	ensembl:ENSG00000179950(gene)|ensembl:ENST00000527197(transcript)|intact:EBI-1053259(isoform-parent)|uniprotkb:Q9UHX1-6(isoform-parent)|entrezgene/locuslink:22827(identity)	-	crc64:27D26E4252A788E2	isoform-comment:"Contains a glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) at position 14."	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:t0fwQOOum/AO/xL8vhZdF2EGymo559292	rogid:rSsTImwmpEAWMCxLzF5Y4zVdeFM9606	intact-crc:A2BE122D4B9CD457|rigid:8EH56eX/wnavTFpdm70DHzxrVZI	false	-	sufficient binding region:15-513	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UHX1-5	uniprotkb:P49955	intact:EBI-11526420|ensembl:ENSP00000395417|ensembl:ENSP00000478209	intact:EBI-664|uniprotkb:D6W0B5|ensemblfungi:YMR288W	psi-mi:q9uhx1-5(display_long)|uniprotkb:PUF60(gene name)|psi-mi:PUF60(display_short)|uniprotkb:"60 kDa poly(U)-binding-splicing factor"(gene name synonym)|uniprotkb:FIR(gene name synonym)|uniprotkb:FUSE-binding protein-interacting repressor(gene name synonym)|uniprotkb:ROBPI(gene name synonym)|uniprotkb:Ro-binding protein 1(gene name synonym)|uniprotkb:SIAHBP1(gene name synonym)|uniprotkb:Siah-binding protein 1(gene name synonym)	psi-mi:sf3b1_yeast(display_long)|uniprotkb:YMR288W(locus name)|uniprotkb:YM8021.14(orf name)|uniprotkb:HSH155(gene name)|psi-mi:HSH155(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11532848|imex:IM-24995-1100	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-1053259(isoform-parent)|ensembl:ENSG00000179950(gene)|ensembl:ENSG00000274081(gene)|ensembl:ENST00000456095(transcript)|ensembl:ENST00000620953(transcript)|entrezgene/locuslink:22827(identity)	refseq:NP_014015.1|sgd:S000004901|dip:DIP-2628N|mint:P49955|ensemblfungi:YMR288W(gene)|ensemblfungi:YMR288W_mRNA(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005686"(U2 snRNP)|go:"GO:0071004"(U2-type prespliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR038737|rcsb pdb:5GM6|rcsb pdb:5LQW|rcsb pdb:5NRL|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:6G90|sgd:YMR288W(identity)	-	isoform-comment:"Contains a glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) at position 14."	crc64:27D26E4252A788E2	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:PSbIU++DIL6ysF0ccd3ZHzeJ5rs9606	rogid:t0fwQOOum/AO/xL8vhZdF2EGymo559292	intact-crc:D0401D53B60385AE|rigid:WDsds/ohoeSWpFKVxrSEtMUSDIU	false	sufficient binding region:15-530	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UHX1-2	uniprotkb:P49955	intact:EBI-11529177|ensembl:ENSP00000322036|ensembl:ENSP00000478495	intact:EBI-664|uniprotkb:D6W0B5|ensemblfungi:YMR288W	psi-mi:q9uhx1-2(display_long)|uniprotkb:PUF60(gene name)|psi-mi:PUF60(display_short)|uniprotkb:"60 kDa poly(U)-binding-splicing factor"(gene name synonym)|uniprotkb:FIR(gene name synonym)|uniprotkb:FUSE-binding protein-interacting repressor(gene name synonym)|uniprotkb:ROBPI(gene name synonym)|uniprotkb:Ro-binding protein 1(gene name synonym)|uniprotkb:SIAHBP1(gene name synonym)|uniprotkb:Siah-binding protein 1(gene name synonym)	psi-mi:sf3b1_yeast(display_long)|uniprotkb:YMR288W(locus name)|uniprotkb:YM8021.14(orf name)|uniprotkb:HSH155(gene name)|psi-mi:HSH155(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11532839|imex:IM-24995-1099	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-1053259(isoform-parent)|ensembl:ENSG00000179950(gene)|ensembl:ENSG00000274081(gene)|ensembl:ENST00000349157(transcript)|ensembl:ENST00000612237(transcript)|uniprotkb:Q9UHX1-2(isoform-parent)|entrezgene/locuslink:22827(identity)	refseq:NP_014015.1|sgd:S000004901|dip:DIP-2628N|mint:P49955|ensemblfungi:YMR288W(gene)|ensemblfungi:YMR288W_mRNA(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005686"(U2 snRNP)|go:"GO:0071004"(U2-type prespliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR038737|rcsb pdb:5GM6|rcsb pdb:5LQW|rcsb pdb:5NRL|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:6G90|sgd:YMR288W(identity)	-	-	crc64:27D26E4252A788E2	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:snVN9Lw5+MP2/aiq4z08ANwvr209606	rogid:t0fwQOOum/AO/xL8vhZdF2EGymo559292	intact-crc:2EE55C5D1F9005F5|rigid:+F97wpeDmVKWuj1/V1IUtVEp+iQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49723	uniprotkb:Q9H4P4	intact:EBI-15251|uniprotkb:Q66R92|uniprotkb:D6VUW4|ensemblfungi:YGR180C	intact:EBI-2130266|uniprotkb:B2RBT8|uniprotkb:O75598|intact:EBI-2563208|intact:EBI-11576203|uniprotkb:A6NFW0|ensembl:ENSP00000342755|ensembl:ENSP00000447303|ensembl:ENSP00000484671	psi-mi:rir4_yeast(display_long)|uniprotkb:RNR4(gene name)|psi-mi:RNR4(display_short)|uniprotkb:YGR180C(locus name)|uniprotkb:CRT3(gene name synonym)|uniprotkb:Ribonucleotide reductase small subunit 2(gene name synonym)|uniprotkb:Ribonucleotide reductase R2 subunit 2(gene name synonym)	psi-mi:rnf41_human(display_long)|uniprotkb:RNF41(gene name)|psi-mi:RNF41(display_short)|uniprotkb:FLRF(gene name synonym)|uniprotkb:NRDP1(gene name synonym)|uniprotkb:RING finger protein 41(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase NRDP1(gene name synonym)|uniprotkb:SBBI03(orf name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11532830|imex:IM-24995-1098	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003412|refseq:NP_011696.3|ensemblfungi:YGR180C(gene)|ensemblfungi:YGR180C_mRNA(transcript)|go:"GO:0004748"(ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005971"(ribonucleoside-diphosphate reductase complex)|go:"GO:0006260"(DNA replication)|go:"GO:0009263"(deoxyribonucleotide biosynthetic process)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR000358(Ribonucleotide reductase)|interpro:IPR012348(Ribonucleotide reductase-related)|interpro:IPR030475|interpro:IPR033909|rcsb pdb:1JK0|rcsb pdb:1SMS|rcsb pdb:1ZZD|interpro:IPR009078(Ferritin/ribonucleotide reductase-like)|dip:DIP-5381N|mint:P49723|sgd:YGR180C(identity)	refseq:XP_011536036.1|refseq:XP_011536037.1|refseq:NP_001229755.1|refseq:NP_005776.1|refseq:NP_919340.1|refseq:NP_919339.1|refseq:XP_005268618.1|ensembl:ENSG00000181852(gene)|ensembl:ENST00000345093(transcript)|ensembl:ENST00000552656(transcript)|ensembl:ENST00000615206(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:2000377"(regulation of reactive oxygen species metabolic process)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013010(Zinc finger, SIAH-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR015036(USP8 interacting)|interpro:IPR017907|interpro:IPR037255|rcsb pdb:2FZP|rcsb pdb:2GWF|reactome:R-HSA-1358803|reactome:R-HSA-983168|entrezgene/locuslink:10193(identity)	-	crc64:712853F2D87D3972	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:/Mx5xMzGpJSBsCDX8nwJMacQ6d4559292	rogid:jthVZwxUECSdqeJ2jZQ5UL28kDY9606	intact-crc:8FFB2533E7F9B4AB|rigid:5hHeel0/IkqZUsqHDInWX+FA8ZQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49723	uniprotkb:P63279	intact:EBI-15251|uniprotkb:Q66R92|uniprotkb:D6VUW4|ensemblfungi:YGR180C	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	psi-mi:rir4_yeast(display_long)|uniprotkb:RNR4(gene name)|psi-mi:RNR4(display_short)|uniprotkb:YGR180C(locus name)|uniprotkb:CRT3(gene name synonym)|uniprotkb:Ribonucleotide reductase small subunit 2(gene name synonym)|uniprotkb:Ribonucleotide reductase R2 subunit 2(gene name synonym)	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11532821|imex:IM-24995-1097	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003412|refseq:NP_011696.3|ensemblfungi:YGR180C(gene)|ensemblfungi:YGR180C_mRNA(transcript)|go:"GO:0004748"(ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005971"(ribonucleoside-diphosphate reductase complex)|go:"GO:0006260"(DNA replication)|go:"GO:0009263"(deoxyribonucleotide biosynthetic process)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR000358(Ribonucleotide reductase)|interpro:IPR012348(Ribonucleotide reductase-related)|interpro:IPR030475|interpro:IPR033909|rcsb pdb:1JK0|rcsb pdb:1SMS|rcsb pdb:1ZZD|interpro:IPR009078(Ferritin/ribonucleotide reductase-like)|dip:DIP-5381N|mint:P49723|sgd:YGR180C(identity)	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N|entrezgene/locuslink:7329(identity)	-	crc64:712853F2D87D3972	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:/Mx5xMzGpJSBsCDX8nwJMacQ6d4559292	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	intact-crc:1F4B1B07115FA0AB|rigid:B30fmCZAgY+r6nzkEimWDZSwJr8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49090	uniprotkb:P26641	intact:EBI-3048|uniprotkb:E9P8Y0|uniprotkb:D6VUQ6|ensemblfungi:YGR124W	intact:EBI-351467|uniprotkb:Q6PJ62|uniprotkb:Q6PK31|uniprotkb:Q96CU2|uniprotkb:Q9P196|intact:EBI-2321928|uniprotkb:B4DTG2|ensembl:ENSP00000331901	psi-mi:asns2_yeast(display_long)|uniprotkb:ASN2(gene name)|psi-mi:ASN2(display_short)|uniprotkb:YGR124W(locus name)|uniprotkb:G6358(orf name)|uniprotkb:Glutamine-dependent asparagine synthetase 2(gene name synonym)	psi-mi:ef1g_human(display_long)|uniprotkb:PRO1608(orf name)|uniprotkb:EEF1G(gene name)|psi-mi:EEF1G(display_short)|uniprotkb:EF1G(gene name synonym)|uniprotkb:eEF-1B gamma(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11532811|imex:IM-24995-1096	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011640.1|sgd:S000003356|dip:DIP-5189N|mint:P49090|ensemblfungi:YGR124W(gene)|ensemblfungi:YGR124W_mRNA(transcript)|go:"GO:0004066"("asparagine synthase (glutamine-hydrolyzing) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006529"(asparagine biosynthetic process)|go:"GO:0006541"(glutamine metabolic process)|go:"GO:0070981"(L-asparagine biosynthetic process)|interpro:IPR001962(Asparagine synthase)|interpro:IPR006426(Asparagine synthase, glutamine-hydrolyzing)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR017932|interpro:IPR029055|interpro:IPR033738|reactome:R-SCE-8963693|sgd:YGR124W(identity)	refseq:NP_001395.1|ensembl:ENSG00000254772(gene)|ensembl:ENST00000329251(transcript)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006414"(translational elongation)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001662(Translation elongation factor EF1B, gamma chain, conserved)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR036249|interpro:IPR036282|interpro:IPR036433|interpro:IPR040079|mint:P26641|rcsb pdb:1PBU|rcsb pdb:5DQS|rcsb pdb:5JPO|reactome:R-HSA-156842|dip:DIP-32516N|entrezgene/locuslink:1937(identity)	-	crc64:2809F3F0FEDE4183	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:h8FNSX14kWwOuKbbuLZsdxrqaXU559292	rogid:biVN96umeEdPm/wvPN4VwbSRHTs9606	intact-crc:06E714109B55BC51|rigid:K8jmAk945MRBrNKC+V+zagQ14uU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96G97-4	uniprotkb:P52870	intact:EBI-10178113|ensembl:ENSP00000354032|ensembl:ENSP00000433888|ensembl:ENSP00000505838	intact:EBI-16410|ensemblfungi:YER087C-B|uniprotkb:D3DLZ4	psi-mi:q96g97-4(display_long)|uniprotkb:Bernardinelli-Seip congenital lipodystrophy type 2 protein(gene name synonym)|uniprotkb:BSCL2(gene name)|psi-mi:BSCL2(display_short)	psi-mi:sc6b1_yeast(display_long)|uniprotkb:Sec61 complex subunit SBH1(gene name synonym)|uniprotkb:YER087BC(orf name)|uniprotkb:YER087C-B(locus name)|uniprotkb:SBH1(gene name)|psi-mi:SBH1(display_short)|uniprotkb:SEB1(gene name synonym)|uniprotkb:Sec61 complex subunit beta(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11532930|imex:IM-24995-1108	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000168000(gene)|ensembl:ENST00000360796(transcript)|ensembl:ENST00000524862(transcript)|ensembl:ENST00000679883(transcript)|intact:EBI-741806(isoform-parent)|uniprotkb:Q96G97-4(isoform-parent)|entrezgene/locuslink:26580(identity)	ensemblfungi:YER087C-B(gene)|ensemblfungi:YER087C-B_mRNA(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|interpro:IPR016482(Preprotein translocase Sec, Sec61-beta subunit, eukarya)|interpro:IPR030671|rcsb pdb:6N3Q|rcsb pdb:6ND1|rcsb pdb:7AFT|rcsb pdb:7KAH|rcsb pdb:7KAI|sgd:S000002128|rcsb pdb:7KAJ|rcsb pdb:7KAO|rcsb pdb:7KAP|rcsb pdb:7KAQ|rcsb pdb:7KAR|rcsb pdb:7KAS|rcsb pdb:7KAT|rcsb pdb:7KAU|rcsb pdb:7KB5|refseq:NP_011011.3|dip:DIP-5681N|mint:P52870|sgd:YER087C-A(identity)	-	isoform-comment:No experimental confirmation available.	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Kewl3FQYPECmEGogRRGyAethllI9606	rogid:9cYnDPhmMpAOdB2GV5TxikzpjI0559292	intact-crc:A4442ADE37497271|rigid:9CIBlAnJj1YRJCicuLOS1cjr4Xc	false	sufficient binding region:65-462	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96BA8	uniprotkb:P52870	intact:EBI-6942903|ensembl:ENSP00000481956|intact:MINT-268046|intact:MINT-8162577|uniprotkb:Q8N2D5|uniprotkb:Q96CP0	intact:EBI-16410|ensemblfungi:YER087C-B|uniprotkb:D3DLZ4	psi-mi:cr3l1_human(display_long)|uniprotkb:CREB3L1(gene name)|psi-mi:CREB3L1(display_short)|uniprotkb:OASIS(gene name synonym)|uniprotkb:PSEC0238(orf name)|uniprotkb:Old astrocyte specifically-induced substance(gene name synonym)	psi-mi:sc6b1_yeast(display_long)|uniprotkb:Sec61 complex subunit SBH1(gene name synonym)|uniprotkb:YER087BC(orf name)|uniprotkb:YER087C-B(locus name)|uniprotkb:SBH1(gene name)|psi-mi:SBH1(display_short)|uniprotkb:SEB1(gene name synonym)|uniprotkb:Sec61 complex subunit beta(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11532920|imex:IM-24995-1107	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157613(gene)|ensembl:ENST00000621158(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0070278"(extracellular matrix constituent secretion)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029805|mint:Q96BA8|reactome:R-HSA-8874211|refseq:NP_443086.1|entrezgene/locuslink:90993(identity)	ensemblfungi:YER087C-B(gene)|ensemblfungi:YER087C-B_mRNA(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|interpro:IPR016482(Preprotein translocase Sec, Sec61-beta subunit, eukarya)|interpro:IPR030671|rcsb pdb:6N3Q|rcsb pdb:6ND1|rcsb pdb:7AFT|rcsb pdb:7KAH|rcsb pdb:7KAI|sgd:S000002128|rcsb pdb:7KAJ|rcsb pdb:7KAO|rcsb pdb:7KAP|rcsb pdb:7KAQ|rcsb pdb:7KAR|rcsb pdb:7KAS|rcsb pdb:7KAT|rcsb pdb:7KAU|rcsb pdb:7KB5|refseq:NP_011011.3|dip:DIP-5681N|mint:P52870|sgd:YER087C-A(identity)	-	comment:mint|function:"Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE"	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:sMWUFmBeBBCO+T0Y2CuB/un1lBg9606	rogid:9cYnDPhmMpAOdB2GV5TxikzpjI0559292	intact-crc:CCBD087C273B269D|rigid:JJlwOt6m3hesNRsZyg8xVuaOAKY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P52870	uniprotkb:Q969F0	intact:EBI-16410|ensemblfungi:YER087C-B|uniprotkb:D3DLZ4	intact:EBI-743099|ensembl:ENSP00000359375	psi-mi:sc6b1_yeast(display_long)|uniprotkb:Sec61 complex subunit SBH1(gene name synonym)|uniprotkb:YER087BC(orf name)|uniprotkb:YER087C-B(locus name)|uniprotkb:SBH1(gene name)|psi-mi:SBH1(display_short)|uniprotkb:SEB1(gene name synonym)|uniprotkb:Sec61 complex subunit beta(gene name synonym)	psi-mi:fate1_human(display_long)|uniprotkb:Tumor antigen BJ-HCC-2(gene name synonym)|uniprotkb:Cancer/testis antigen 43(gene name synonym)|uniprotkb:FATE1(gene name)|psi-mi:FATE1(display_short)|uniprotkb:FATE(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11532911|imex:IM-24995-1106	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YER087C-B(gene)|ensemblfungi:YER087C-B_mRNA(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|interpro:IPR016482(Preprotein translocase Sec, Sec61-beta subunit, eukarya)|interpro:IPR030671|rcsb pdb:6N3Q|rcsb pdb:6ND1|rcsb pdb:7AFT|rcsb pdb:7KAH|rcsb pdb:7KAI|sgd:S000002128|rcsb pdb:7KAJ|rcsb pdb:7KAO|rcsb pdb:7KAP|rcsb pdb:7KAQ|rcsb pdb:7KAR|rcsb pdb:7KAS|rcsb pdb:7KAT|rcsb pdb:7KAU|rcsb pdb:7KB5|refseq:NP_011011.3|dip:DIP-5681N|mint:P52870|sgd:YER087C-A(identity)	refseq:NP_149076.1|ensembl:ENSG00000147378(gene)|ensembl:ENST00000370350(transcript)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|go:"GO:0051562"(negative regulation of mitochondrial calcium ion concentration)|interpro:IPR039153|interpro:IPR039433|mint:Q969F0|entrezgene/locuslink:89885(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:9cYnDPhmMpAOdB2GV5TxikzpjI0559292	rogid:Nm1N6lO92MHr5rIKC007oouF5RE9606	intact-crc:0712E4EF2C08CF27|rigid:c0v+1AqiLG1L7oPfiRG1Ud9D9w8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:J3KQ12	uniprotkb:P52870	intact:EBI-11532900|ensembl:ENSP00000385332	intact:EBI-16410|ensemblfungi:YER087C-B|uniprotkb:D3DLZ4	psi-mi:j3kq12_human(display_long)|uniprotkb:hCG_2020143(orf name)|uniprotkb:BSCL2(gene name)|psi-mi:BSCL2(display_short)	psi-mi:sc6b1_yeast(display_long)|uniprotkb:Sec61 complex subunit SBH1(gene name synonym)|uniprotkb:YER087BC(orf name)|uniprotkb:YER087C-B(locus name)|uniprotkb:SBH1(gene name)|psi-mi:SBH1(display_short)|uniprotkb:SEB1(gene name synonym)|uniprotkb:Sec61 complex subunit beta(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11532898|imex:IM-24995-1105	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000168000(gene)|ensembl:ENST00000405837(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019915"(lipid storage)|interpro:IPR009617(Protein of unknown function DUF1226)|entrezgene/locuslink:26580(identity)	ensemblfungi:YER087C-B(gene)|ensemblfungi:YER087C-B_mRNA(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|interpro:IPR016482(Preprotein translocase Sec, Sec61-beta subunit, eukarya)|interpro:IPR030671|rcsb pdb:6N3Q|rcsb pdb:6ND1|rcsb pdb:7AFT|rcsb pdb:7KAH|rcsb pdb:7KAI|sgd:S000002128|rcsb pdb:7KAJ|rcsb pdb:7KAO|rcsb pdb:7KAP|rcsb pdb:7KAQ|rcsb pdb:7KAR|rcsb pdb:7KAS|rcsb pdb:7KAT|rcsb pdb:7KAU|rcsb pdb:7KB5|refseq:NP_011011.3|dip:DIP-5681N|mint:P52870|sgd:YER087C-A(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:/q8SqeciXG5EVZxzVJRfX6gvRjY9606	rogid:9cYnDPhmMpAOdB2GV5TxikzpjI0559292	intact-crc:2391B1D0CEDAABDD|rigid:Qy2mgAPlh4qPTWcLYn9Ed+TxEzo	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9NXK8	uniprotkb:P52286	intact:EBI-719790|uniprotkb:Q9H5K4|uniprotkb:B3KSJ8|ensembl:ENSP00000247977	intact:EBI-4090|uniprotkb:Q07186|uniprotkb:D6VSW0|ensemblfungi:YDR328C	psi-mi:fxl12_human(display_long)|uniprotkb:F-box and leucine-rich repeat protein 12(gene name synonym)|uniprotkb:F-box protein FBL12(gene name synonym)|uniprotkb:FBXL12(gene name)|psi-mi:FBXL12(display_short)|uniprotkb:FBL12(gene name synonym)	psi-mi:skp1_yeast(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:CBF3D(gene name synonym)|uniprotkb:YDR328C(locus name)|uniprotkb:D9798.14(orf name)|uniprotkb:Centromere DNA-binding protein complex CBF3 subunit D(gene name synonym)|uniprotkb:E3 ubiquitin ligase complex SCF subunit SKP1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11532889|imex:IM-24995-1104	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060173.1|refseq:NP_001303865.1|refseq:NP_001303866.1|refseq:NP_001303867.1|refseq:NP_001303868.1|refseq:NP_001303869.1|refseq:NP_001303870.1|refseq:NP_001303871.1|ensembl:ENSG00000127452(gene)|ensembl:ENST00000247977(transcript)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR032675|interpro:IPR036047|mint:Q9NXK8|reactome:R-HSA-8951664|reactome:R-HSA-983168|entrezgene/locuslink:54850(identity)	sgd:S000002736|refseq:NP_010615.3|dip:DIP-1236N|mint:P52286|ensemblfungi:YDR328C(gene)|ensemblfungi:YDR328C_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0000921"(septin ring assembly)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0010458"(exit from mitosis)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031518"(CBF3 complex)|go:"GO:0034622"|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0043291"(RAVE complex)|go:"GO:0045116"(protein neddylation)|go:"GO:0051382"(kinetochore assembly)|go:"GO:0097602"(cullin family protein binding)|go:"GO:2000766"(negative regulation of cytoplasmic translation)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|rcsb pdb:1NEX|rcsb pdb:3MKS|rcsb pdb:3V7D|rcsb pdb:5AN3|rcsb pdb:6F07|rcsb pdb:6FE8|rcsb pdb:6GSA|rcsb pdb:6GYP|rcsb pdb:6GYS|rcsb pdb:6GYU|rcsb pdb:7K79|reactome:R-SCE-174113|reactome:R-SCE-68949|reactome:R-SCE-8854050|reactome:R-SCE-8951664|reactome:R-SCE-983168|sgd:YDR328C(identity)	-	-	crc64:746DDE6470A69432	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:b+3vZLMbZvEww+hdTa3YnLkPiC49606	rogid:HO5Uz+KzzWNBubxoXRDNTVi8eIA559292	intact-crc:45CAAE4C60F2F145|rigid:YrtKB5yhPOVeqJBX+IeEhvzitc4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9NVF7	uniprotkb:P52286	intact:EBI-740282|uniprotkb:O75070|ensembl:ENSP00000355827|uniprotkb:E9PEM8	intact:EBI-4090|uniprotkb:Q07186|uniprotkb:D6VSW0|ensemblfungi:YDR328C	psi-mi:fbx28_human(display_long)|uniprotkb:FBXO28(gene name)|psi-mi:FBXO28(display_short)|uniprotkb:KIAA0483(gene name synonym)|uniprotkb:CENP-30(gene name synonym)	psi-mi:skp1_yeast(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:CBF3D(gene name synonym)|uniprotkb:YDR328C(locus name)|uniprotkb:D9798.14(orf name)|uniprotkb:Centromere DNA-binding protein complex CBF3 subunit D(gene name synonym)|uniprotkb:E3 ubiquitin ligase complex SCF subunit SKP1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11532880|imex:IM-24995-1103	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055991.1|ensembl:ENSG00000143756(gene)|ensembl:ENST00000366862(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000776"(kinetochore)|go:"GO:0042802"(identical protein binding)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR036047|interpro:IPR039719|refseq:NP_001129587.1|dip:DIP-56683N|entrezgene/locuslink:23219(identity)	sgd:S000002736|refseq:NP_010615.3|dip:DIP-1236N|mint:P52286|ensemblfungi:YDR328C(gene)|ensemblfungi:YDR328C_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0000921"(septin ring assembly)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0010458"(exit from mitosis)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031518"(CBF3 complex)|go:"GO:0034622"|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0043291"(RAVE complex)|go:"GO:0045116"(protein neddylation)|go:"GO:0051382"(kinetochore assembly)|go:"GO:0097602"(cullin family protein binding)|go:"GO:2000766"(negative regulation of cytoplasmic translation)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|rcsb pdb:1NEX|rcsb pdb:3MKS|rcsb pdb:3V7D|rcsb pdb:5AN3|rcsb pdb:6F07|rcsb pdb:6FE8|rcsb pdb:6GSA|rcsb pdb:6GYP|rcsb pdb:6GYS|rcsb pdb:6GYU|rcsb pdb:7K79|reactome:R-SCE-174113|reactome:R-SCE-68949|reactome:R-SCE-8854050|reactome:R-SCE-8951664|reactome:R-SCE-983168|sgd:YDR328C(identity)	-	-	crc64:746DDE6470A69432	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Iz7yI5ugv60KqYH7MAdBjXjw2vs9606	rogid:HO5Uz+KzzWNBubxoXRDNTVi8eIA559292	intact-crc:ACB3F641DB612204|rigid:9LW09gw2oiP7ymssRKHBhvSsnlc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P50076	uniprotkb:Q96BA8	intact:EBI-7301533|intact:UNK-5379069|uniprotkb:D6VV08|ensemblfungi:YGR227W	intact:EBI-6942903|ensembl:ENSP00000481956|intact:MINT-268046|intact:MINT-8162577|uniprotkb:Q8N2D5|uniprotkb:Q96CP0	psi-mi:alg10_yeast(display_long)|uniprotkb:Alpha-1,2-glucosyltransferase ALG10-A(gene name synonym)|uniprotkb:DIE2(gene name)|psi-mi:DIE2(display_short)|uniprotkb:ALG10(gene name synonym)|uniprotkb:G8547(orf name)|uniprotkb:YGR227W(locus name)|uniprotkb:Alpha-2-glucosyltransferase ALG10(gene name synonym)|uniprotkb:Dolichyl-phosphoglucose-dependent glucosyltransferase ALG10(gene name synonym)|uniprotkb:Asparagine-linked glycosylation protein 10(gene name synonym)	psi-mi:cr3l1_human(display_long)|uniprotkb:CREB3L1(gene name)|psi-mi:CREB3L1(display_short)|uniprotkb:OASIS(gene name synonym)|uniprotkb:PSEC0238(orf name)|uniprotkb:Old astrocyte specifically-induced substance(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11532870|imex:IM-24995-1102	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003459|refseq:NP_011743.2|interpro:IPR016900(Alpha-1, 2 glucosyltransferase Alg10)|ensemblfungi:YGR227W(gene)|ensemblfungi:YGR227W_mRNA(transcript)|go:"GO:0004583"(dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0006488"(dolichol-linked oligosaccharide biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|go:"GO:0106073"(dolichyl pyrophosphate Glc2Man9GlcNAc2 alpha-1,2-glucosyltransferase activity)|sgd:YGR227W(identity)	ensembl:ENSG00000157613(gene)|ensembl:ENST00000621158(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0070278"(extracellular matrix constituent secretion)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029805|mint:Q96BA8|reactome:R-HSA-8874211|refseq:NP_443086.1|entrezgene/locuslink:90993(identity)	-	comment:mint|function:"Adds the third glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation. Transfers glucose from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide Glc(2)Man(9)GlcNAc(2)-PP-Dol"	comment:mint|function:"Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE"	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:CgcGK+aNZdx786YvH8/CbJHTirw559292	rogid:sMWUFmBeBBCO+T0Y2CuB/un1lBg9606	intact-crc:0DDAC424AC856C66|rigid:tBHOTfqU6XaQ5rubwjPCIwnswLA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8IYA8	uniprotkb:P53038	intact:EBI-8638439|intact:EBI-28969497|ensembl:ENSP00000296449|ensembl:ENSP00000391788|ensembl:ENSP00000407837|uniprotkb:C9JJL0|uniprotkb:Q96LP7|intact:MINT-8162095|uniprotkb:Q05DG9	intact:EBI-19106|uniprotkb:D6VUN1|ensemblfungi:YGR099W	psi-mi:iho1_human(display_long)|uniprotkb:IHO1(gene name)|psi-mi:IHO1(display_short)|uniprotkb:CCDC36(gene name synonym)|uniprotkb:Cancer/testis antigen 74(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 36(gene name synonym)	psi-mi:tel2_yeast(display_long)|uniprotkb:YGR099W(locus name)|uniprotkb:TEL2(gene name)|psi-mi:TEL2(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11532997|imex:IM-24995-1115	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000296449|ensembl:ENST00000366429|ensembl:ENSP00000403700|ensembl:ENSP00000391788|ensembl:ENSP00000407837|ensembl:ENSG00000173421(gene)|ensembl:ENST00000296449(transcript)|ensembl:ENST00000438782(transcript)|ensembl:ENST00000452691(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0006310"(DNA recombination)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0042138"(meiotic DNA double-strand break formation)|go:"GO:0048477"(oogenesis)|go:"GO:0060629"(regulation of homologous chromosome segregation)|interpro:IPR031529|mint:Q8IYA8|refseq:XP_011531974.1|refseq:XP_011531975.1|refseq:NP_001128669.1|refseq:NP_835467.2|refseq:XP_006713187.1|entrezgene/locuslink:339834(identity)	sgd:S000003331|ensemblfungi:YGR099W(gene)|ensemblfungi:YGR099W_mRNA(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0005829"(cytosol)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0034502"(protein localization to chromosome)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0070209"(ASTRA complex)|interpro:IPR019337|interpro:IPR038528|rcsb pdb:3O4Z|refseq:NP_011613.3|dip:DIP-1245N|mint:P53038|sgd:YGR099W(identity)	-	comment:mint	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:+TNQLExkhmC1NWqsE240Cx7zFVU9606	rogid:SZibPBili0M8YgHIwxf+sKkLk+M559292	intact-crc:E7CAF888ABB3CC68|rigid:XUwRPk82ZxXogZH7flupK9k8kbk	false	sufficient binding region:11-594	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P53038	uniprotkb:Q5JST6	intact:EBI-19106|uniprotkb:D6VUN1|ensemblfungi:YGR099W	intact:EBI-2349927|uniprotkb:Q9H653|uniprotkb:Q5JST8|uniprotkb:Q68DK4|uniprotkb:Q8NEI0|intact:EBI-28971886|ensembl:ENSP00000404232	psi-mi:tel2_yeast(display_long)|uniprotkb:YGR099W(locus name)|uniprotkb:TEL2(gene name)|psi-mi:TEL2(display_short)	psi-mi:efhc2_human(display_long)|uniprotkb:EFHC2(gene name)|psi-mi:EFHC2(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11532988|imex:IM-24995-1114	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003331|ensemblfungi:YGR099W(gene)|ensemblfungi:YGR099W_mRNA(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0005829"(cytosol)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0034502"(protein localization to chromosome)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0070209"(ASTRA complex)|interpro:IPR019337|interpro:IPR038528|rcsb pdb:3O4Z|refseq:NP_011613.3|dip:DIP-1245N|mint:P53038|sgd:YGR099W(identity)	ensembl:ENSP00000404232|refseq:NP_079460.2|ensembl:ENSG00000183690(gene)|ensembl:ENST00000420999(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005930"(axoneme)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0060285"(cilium-dependent cell motility)|go:"GO:0072686"(mitotic spindle)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR006602(Region of unknown function DM10)|interpro:IPR011992(EF-Hand type)|interpro:IPR040193|rcsb pdb:2Z13|rcsb pdb:2Z14|entrezgene/locuslink:80258(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:SZibPBili0M8YgHIwxf+sKkLk+M559292	rogid:O1XriQSkLcYkk7H7AlanQ1FKIBY9606	intact-crc:4438450AE98165DB|rigid:9giCatqt8PuQndlqWKpR+671cbI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P53012	uniprotkb:Q8N6L0	intact:EBI-16742|ensemblfungi:YGL126W|uniprotkb:E9P8W2|uniprotkb:D6VU22	intact:EBI-749265|uniprotkb:Q96MC3|ensembl:ENSP00000404220	psi-mi:scs3_yeast(display_long)|uniprotkb:SCS3(gene name)|psi-mi:SCS3(display_short)|uniprotkb:YGL126W(locus name)|uniprotkb:G2868(orf name)|uniprotkb:FIT2B(gene name synonym)|uniprotkb:FIT family protein SCS3(gene name synonym)	psi-mi:kash5_human(display_long)|uniprotkb:KASH5(gene name)|psi-mi:KASH5(display_short)|uniprotkb:CCDC155(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 155(gene name synonym)|uniprotkb:KASH domain-containing protein 5(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11532979|imex:IM-24995-1113	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011389.3|ensemblfungi:YGL126W(gene)|ensemblfungi:YGL126W_mRNA(transcript)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006644"(phospholipid metabolic process)|go:"GO:0008654"(phospholipid biosynthetic process)|go:"GO:0016818"(hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides)|go:"GO:0019915"(lipid storage)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0034389"(lipid droplet organization)|go:"GO:0140042"(lipid droplet formation)|go:"GO:1900480"(regulation of diacylglycerol biosynthetic process)|go:"GO:1900481"(negative regulation of diacylglycerol biosynthetic process)|interpro:IPR019388|go:"GO:0005783"(endoplasmic reticulum)|sgd:S000003094|reactome:R-SCE-8964572|dip:DIP-1209N|sgd:YGL126W(identity)	refseq:NP_653289.3|ensembl:ENSG00000161609(gene)|ensembl:ENST00000447857(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034397"(telomere localization)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051225"(spindle assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0090172"(microtubule cytoskeleton organization involved in homologous chromosome segregation)|go:"GO:0090220"(chromosome localization to nuclear envelope involved in homologous chromosome segregation)|go:"GO:0090619"(meiotic spindle pole)|interpro:IPR011992(EF-Hand type)|interpro:IPR028168|interpro:IPR028170|interpro:IPR039508|mint:Q8N6L0|rcsb pdb:6R2I|rcsb pdb:6WMF|entrezgene/locuslink:147872(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Hv4EhOlOeuhRkn8ZMn7vejwqoag559292	rogid:Wl9L7AcvDHCZuKjYLn8QgGIbZTc9606	intact-crc:53346CE1EBC30E2C|rigid:AiGxQzGNJCywWak4v2aAkBXyVv4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9HCM9-2	uniprotkb:P52917	intact:EBI-11523450|ensembl:ENSP00000365847|ensembl:ENSP00000373095|ensembl:ENSP00000373097|ensembl:ENSP00000379797|ensembl:ENSP00000379800|ensembl:ENSP00000383486|ensembl:ENSP00000387445|ensembl:ENSP00000389198|ensembl:ENSP00000389852|ensembl:ENSP00000392130|ensembl:ENSP00000394353|ensembl:ENSP00000396986|ensembl:ENSP00000398956|ensembl:ENSP00000401071|ensembl:ENSP00000401184|ensembl:ENSP00000404340|ensembl:ENSP00000404904|ensembl:ENSP00000411582|ensembl:ENSP00000412743|ensembl:ENSP00000414525|ensembl:ENSP00000415259	intact:EBI-20475|uniprotkb:D6W4H4|ensemblfungi:YPR173C	psi-mi:q9hcm9-2(display_long)|uniprotkb:TRIM39(gene name)|psi-mi:TRIM39(display_short)|uniprotkb:RING finger protein 23(gene name synonym)|uniprotkb:RNF23(gene name synonym)|uniprotkb:TFP(gene name synonym)|uniprotkb:Testis-abundant finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 39(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM39(gene name synonym)|uniprotkb:TIM39beta(isoform synonym)	psi-mi:vps4_yeast(display_long)|uniprotkb:VPS4(gene name)|psi-mi:VPS4(display_short)|uniprotkb:CSC1(gene name synonym)|uniprotkb:END13(gene name synonym)|uniprotkb:GRD13(gene name synonym)|uniprotkb:DID6(gene name synonym)|uniprotkb:Protein END13(gene name synonym)|uniprotkb:DOA4-independent degradation protein 6(gene name synonym)|uniprotkb:Vacuolar protein-targeting protein 10(gene name synonym)|uniprotkb:VPL4(gene name synonym)|uniprotkb:VPT10(gene name synonym)|uniprotkb:P9705.10(orf name)|uniprotkb:YPR173C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11532969|imex:IM-24995-1112	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-739510(isoform-parent)|ensembl:ENSG00000204599(gene)|ensembl:ENSG00000206495(gene)|ensembl:ENSG00000224994(gene)|ensembl:ENSG00000226437(gene)|ensembl:ENSG00000229929(gene)|ensembl:ENSG00000230308(gene)|ensembl:ENSG00000232839(gene)|ensembl:ENST00000376659(transcript)|ensembl:ENST00000383601(transcript)|ensembl:ENST00000383603(transcript)|ensembl:ENST00000396548(transcript)|ensembl:ENST00000396551(transcript)|ensembl:ENST00000400644(transcript)|ensembl:ENST00000414015(transcript)|ensembl:ENST00000419790(transcript)|ensembl:ENST00000430502(transcript)|ensembl:ENST00000431272(transcript)|ensembl:ENST00000433900(transcript)|ensembl:ENST00000438076(transcript)|ensembl:ENST00000438859(transcript)|ensembl:ENST00000440117(transcript)|ensembl:ENST00000443109(transcript)|ensembl:ENST00000446397(transcript)|ensembl:ENST00000449318(transcript)|ensembl:ENST00000450778(transcript)|ensembl:ENST00000451132(transcript)|ensembl:ENST00000452705(transcript)|ensembl:ENST00000458607(transcript)|uniprotkb:Q9HCM9-2(isoform-parent)|entrezgene/locuslink:56658(identity)	refseq:NP_015499.1|sgd:S000006377|ensemblfungi:YPR173C(gene)|ensemblfungi:YPR173C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0007033"(vacuole organization)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0016197"(endosomal transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045053"(protein retention in Golgi apparatus)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0061709"(reticulophagy)|go:"GO:0070676"(intralumenal vesicle formation)|go:"GO:1990621"(ESCRT IV complex)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR007330(MIT)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR027417|interpro:IPR036181|rcsb pdb:2QP9|rcsb pdb:2QPA|rcsb pdb:2RKO|rcsb pdb:2V6X|rcsb pdb:3EIE|rcsb pdb:3EIH|rcsb pdb:3MHV|rcsb pdb:4NIQ|rcsb pdb:5FVK|rcsb pdb:5FVL|rcsb pdb:5UIE|rcsb pdb:5XMI|rcsb pdb:5XMK|rcsb pdb:6AP1|rcsb pdb:6BMF|rcsb pdb:6NDY|rcsb pdb:6OO2|reactome:R-SCE-917729|reactome:R-SCE-9668328|dip:DIP-1746N|mint:P52917|sgd:YPR173C(identity)	-	-	crc64:E65BCDB19C9510DD	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:UfSn2+IVRxtGomVeDGdZpL7mz5I9606	rogid:qXGTfZcBZ9jWOVjm6tl3wIR/ngM559292	intact-crc:628612ECA68F7C12|rigid:QNirPDE+f0Ap2Ljj1NcZWn7j2PE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P52917	uniprotkb:Q5T124-6	intact:EBI-20475|uniprotkb:D6W4H4|ensemblfungi:YPR173C	intact:EBI-11524408	psi-mi:vps4_yeast(display_long)|uniprotkb:VPS4(gene name)|psi-mi:VPS4(display_short)|uniprotkb:CSC1(gene name synonym)|uniprotkb:END13(gene name synonym)|uniprotkb:GRD13(gene name synonym)|uniprotkb:DID6(gene name synonym)|uniprotkb:Protein END13(gene name synonym)|uniprotkb:DOA4-independent degradation protein 6(gene name synonym)|uniprotkb:Vacuolar protein-targeting protein 10(gene name synonym)|uniprotkb:VPL4(gene name synonym)|uniprotkb:VPT10(gene name synonym)|uniprotkb:P9705.10(orf name)|uniprotkb:YPR173C(locus name)	psi-mi:q5t124-6(display_long)|uniprotkb:UBXN11(gene name)|psi-mi:UBXN11(display_short)|uniprotkb:Colorectal tumor-associated antigen COA-1(gene name synonym)|uniprotkb:SOC(gene name synonym)|uniprotkb:Socius(gene name synonym)|uniprotkb:UBX domain-containing protein 5(gene name synonym)|uniprotkb:UBXD5(gene name synonym)|uniprotkb:PP2243(orf name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11532960|imex:IM-24995-1111	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015499.1|sgd:S000006377|ensemblfungi:YPR173C(gene)|ensemblfungi:YPR173C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0007033"(vacuole organization)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0016197"(endosomal transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045053"(protein retention in Golgi apparatus)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0061709"(reticulophagy)|go:"GO:0070676"(intralumenal vesicle formation)|go:"GO:1990621"(ESCRT IV complex)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR007330(MIT)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR027417|interpro:IPR036181|rcsb pdb:2QP9|rcsb pdb:2QPA|rcsb pdb:2RKO|rcsb pdb:2V6X|rcsb pdb:3EIE|rcsb pdb:3EIH|rcsb pdb:3MHV|rcsb pdb:4NIQ|rcsb pdb:5FVK|rcsb pdb:5FVL|rcsb pdb:5UIE|rcsb pdb:5XMI|rcsb pdb:5XMK|rcsb pdb:6AP1|rcsb pdb:6BMF|rcsb pdb:6NDY|rcsb pdb:6OO2|reactome:R-SCE-917729|reactome:R-SCE-9668328|dip:DIP-1746N|mint:P52917|sgd:YPR173C(identity)	intact:EBI-746004(isoform-parent)|uniprotkb:Q5T124-6(isoform-parent)|entrezgene/locuslink:91544(identity)	-	crc64:E65BCDB19C9510DD	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:qXGTfZcBZ9jWOVjm6tl3wIR/ngM559292	rogid:1YSjG/p2ihcjl4P8KdPCaX2HxiY9606	intact-crc:CBC5596A4496DB7B|rigid:7O1nNDYAqyasMOpQILRuAfgc7y0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9BSE2	uniprotkb:P52870	intact:EBI-8649725|ensembl:ENSP00000295694|ensembl:ENSP00000384748|intact:MINT-8163648|uniprotkb:D3DVB8|uniprotkb:B2RE22	intact:EBI-16410|ensemblfungi:YER087C-B|uniprotkb:D3DLZ4	psi-mi:tmm79_human(display_long)|uniprotkb:MATT(gene name synonym)|uniprotkb:TMEM79(gene name)|psi-mi:TMEM79(display_short)|uniprotkb:Mattrin(gene name synonym)	psi-mi:sc6b1_yeast(display_long)|uniprotkb:Sec61 complex subunit SBH1(gene name synonym)|uniprotkb:YER087BC(orf name)|uniprotkb:YER087C-B(locus name)|uniprotkb:SBH1(gene name)|psi-mi:SBH1(display_short)|uniprotkb:SEB1(gene name synonym)|uniprotkb:Sec61 complex subunit beta(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11532951|imex:IM-24995-1110	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000163472(gene)|ensembl:ENST00000295694(transcript)|ensembl:ENST00000405535(transcript)|go:"GO:0002070"(epithelial cell maturation)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031069"(hair follicle morphogenesis)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0042335"(cuticle development)|go:"GO:0042802"(identical protein binding)|go:"GO:0045055"(regulated exocytosis)|go:"GO:0045684"(positive regulation of epidermis development)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070268"(cornification)|mint:Q9BSE2|refseq:NP_115699.1|entrezgene/locuslink:84283(identity)	ensemblfungi:YER087C-B(gene)|ensemblfungi:YER087C-B_mRNA(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|interpro:IPR016482(Preprotein translocase Sec, Sec61-beta subunit, eukarya)|interpro:IPR030671|rcsb pdb:6N3Q|rcsb pdb:6ND1|rcsb pdb:7AFT|rcsb pdb:7KAH|rcsb pdb:7KAI|sgd:S000002128|rcsb pdb:7KAJ|rcsb pdb:7KAO|rcsb pdb:7KAP|rcsb pdb:7KAQ|rcsb pdb:7KAR|rcsb pdb:7KAS|rcsb pdb:7KAT|rcsb pdb:7KAU|rcsb pdb:7KB5|refseq:NP_011011.3|dip:DIP-5681N|mint:P52870|sgd:YER087C-A(identity)	-	comment:mint	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:QdmILKEdTJzJUhBdigw/4vC4R3o9606	rogid:9cYnDPhmMpAOdB2GV5TxikzpjI0559292	intact-crc:C85A9DEE9A964A4D|rigid:cSjcXahvE4kqU+2ue6xd72Sc1Rg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96HH9	uniprotkb:P52870	intact:EBI-2832937|uniprotkb:Q9H753|uniprotkb:D3DSZ3|uniprotkb:B7Z1F2|uniprotkb:B7Z3R1|uniprotkb:B7Z6D8|uniprotkb:B7Z8T2|ensembl:ENSP00000285689	intact:EBI-16410|ensemblfungi:YER087C-B|uniprotkb:D3DLZ4	psi-mi:grm2b_human(display_long)|uniprotkb:GRAMD2B(gene name)|psi-mi:GRAMD2B(display_short)|uniprotkb:GRAMD3(gene name synonym)|uniprotkb:HCV NS3-transactivated protein 2(gene name synonym)|uniprotkb:NS3TP2(gene name synonym)	psi-mi:sc6b1_yeast(display_long)|uniprotkb:Sec61 complex subunit SBH1(gene name synonym)|uniprotkb:YER087BC(orf name)|uniprotkb:YER087C-B(locus name)|uniprotkb:SBH1(gene name)|psi-mi:SBH1(display_short)|uniprotkb:SEB1(gene name synonym)|uniprotkb:Sec61 complex subunit beta(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11532942|imex:IM-24995-1109	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_016865274.1|refseq:NP_001139791.1|refseq:NP_001139792.1|refseq:NP_001139793.1|refseq:NP_001139794.1|refseq:NP_076416.2|refseq:XP_005272120.1|ensembl:ENSG00000155324(gene)|ensembl:ENST00000285689(transcript)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0042802"(identical protein binding)|interpro:IPR004182(GRAM)|interpro:IPR011993(Pleckstrin homology-type)|entrezgene/locuslink:65983(identity)	ensemblfungi:YER087C-B(gene)|ensemblfungi:YER087C-B_mRNA(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|interpro:IPR016482(Preprotein translocase Sec, Sec61-beta subunit, eukarya)|interpro:IPR030671|rcsb pdb:6N3Q|rcsb pdb:6ND1|rcsb pdb:7AFT|rcsb pdb:7KAH|rcsb pdb:7KAI|sgd:S000002128|rcsb pdb:7KAJ|rcsb pdb:7KAO|rcsb pdb:7KAP|rcsb pdb:7KAQ|rcsb pdb:7KAR|rcsb pdb:7KAS|rcsb pdb:7KAT|rcsb pdb:7KAU|rcsb pdb:7KB5|refseq:NP_011011.3|dip:DIP-5681N|mint:P52870|sgd:YER087C-A(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:6UkVJddV5/mHpLX/rk00jMwCA+k9606	rogid:9cYnDPhmMpAOdB2GV5TxikzpjI0559292	intact-crc:A834C01E00B0181F|rigid:yvhZg8l9r++wGI/kFZEEQLd35DU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P53129	uniprotkb:Q9Y2J4	intact:EBI-23945|uniprotkb:D6VU24|ensemblfungi:YGL124C	intact:EBI-746752|intact:EBI-28986657|ensembl:ENSP00000409999|uniprotkb:Q53EP1|uniprotkb:Q96F99|uniprotkb:Q9UKB4|uniprotkb:A8K6F1|uniprotkb:B7Z5Q1|uniprotkb:E9PHW3	psi-mi:mon1_yeast(display_long)|uniprotkb:YGL124C(locus name)|uniprotkb:G2889(orf name)|uniprotkb:MON1(gene name)|psi-mi:MON1(display_short)|uniprotkb:AUT12(gene name synonym)|uniprotkb:Monensin sensitivity protein 1(gene name synonym)|uniprotkb:Autophagy-related protein 12(gene name synonym)	psi-mi:amol2_human(display_long)|uniprotkb:Leman coiled-coil protein(gene name synonym)|uniprotkb:AMOTL2(gene name)|psi-mi:AMOTL2(display_short)|uniprotkb:KIAA0989(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11533048|imex:IM-24995-1120	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011391.2|sgd:S000003092|dip:DIP-5483N|mint:P53129|ensemblfungi:YGL124C(gene)|ensemblfungi:YGL124C_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006914"(autophagy)|go:"GO:0010314"(phosphatidylinositol-5-phosphate binding)|go:"GO:0016236"(macroautophagy)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0032585"(multivesicular body membrane)|go:"GO:0035658"(Mon1-Ccz1 complex)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044395"(protein targeting to vacuolar membrane)|go:"GO:0048278"(vesicle docking)|interpro:IPR004353(Protein of unknown function DUF254, SAND)|interpro:IPR043970|interpro:IPR043971|interpro:IPR043972|reactome:R-SCE-8876198|sgd:YGL124C(identity)	refseq:NP_001265612.1|refseq:NP_001265614.1|ensembl:ENSG00000114019(gene)|refseq:XP_006713717.1|refseq:NP_057285.3|refseq:XP_011511183.1|ensembl:ENST00000422605(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0003365"(establishment of cell polarity involved in ameboidal cell migration)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0035329"(hippo signaling)|go:"GO:0055037"(recycling endosome)|interpro:IPR009114(Angiomotin)|interpro:IPR024646|mint:Q9Y2J4|reactome:R-HSA-2028269|refseq:XP_016862069.1|refseq:XP_016862070.1|refseq:XP_016862071.1|ensembl:ENST00000249883|ensembl:ENSP00000249883|ensembl:ENSP00000409999|ensembl:ENST00000513145|ensembl:ENSP00000425475|ensembl:ENST00000514516|ensembl:ENSP00000424765|dip:DIP-57510N|entrezgene/locuslink:51421(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:9tNVB/LFcvinM/mEzRj6ezSNCWo559292	rogid:SHtKAcLLnTpSSLwVE7yQ1WECoZk9606	intact-crc:F3398FE5D388AEA8|rigid:4ZMhJLKK2G42jq8MacT3eZcTpvs	false	-	sufficient binding region:314-779	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P43355	uniprotkb:P53102	intact:EBI-740978|ensembl:ENSP00000349085|uniprotkb:O00346|uniprotkb:B2RC81	intact:EBI-24091|uniprotkb:D6VTX1|ensemblfungi:YGL183C	psi-mi:maga1_human(display_long)|uniprotkb:MAGE-1 antigen(gene name synonym)|uniprotkb:Antigen MZ2-E(gene name synonym)|uniprotkb:Cancer/testis antigen 1.1(gene name synonym)|uniprotkb:MAGEA1(gene name)|psi-mi:MAGEA1(display_short)|uniprotkb:MAGE1(gene name synonym)|uniprotkb:MAGE1A(gene name synonym)	psi-mi:mnd1_yeast(display_long)|uniprotkb:MND1(gene name)|psi-mi:MND1(display_short)|uniprotkb:G1604(orf name)|uniprotkb:YGL183C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11533037|imex:IM-24995-1119	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004979.3|ensembl:ENSG00000198681(gene)|ensembl:ENST00000356661(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|interpro:IPR002190(MAGE protein)|interpro:IPR021072|interpro:IPR030093|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|rcsb pdb:1W72|rcsb pdb:3BO8|dip:DIP-54794N|entrezgene/locuslink:4100(identity)	refseq:NP_011332.2|sgd:S000003151|dip:DIP-2673N|ensemblfungi:YGL183C(gene)|ensemblfungi:YGL183C_mRNA(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0007131"(reciprocal meiotic recombination)|interpro:IPR005647(meiotic nuclear division protein 1)|interpro:IPR040453|interpro:IPR040661|sgd:YGL183C(identity)	-	crc64:544EEB1F9F4E9D33	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:6XW3mnTNM3yvOtXmiFbU8Uz3hjA9606	rogid:wGVAo4LTwqSnDsJ+/xC3qIMqZ0k559292	intact-crc:0BA691F71FA82F56|rigid:B89B+XW3buuhr1+8kP6E7kSredc	false	-	sufficient binding region:46-219	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96BA8	uniprotkb:P53053	intact:EBI-6942903|ensembl:ENSP00000481956|intact:MINT-268046|intact:MINT-8162577|uniprotkb:Q8N2D5|uniprotkb:Q96CP0	intact:EBI-5002|uniprotkb:D6VV71|ensemblfungi:YGL263W	psi-mi:cr3l1_human(display_long)|uniprotkb:CREB3L1(gene name)|psi-mi:CREB3L1(display_short)|uniprotkb:OASIS(gene name synonym)|uniprotkb:PSEC0238(orf name)|uniprotkb:Old astrocyte specifically-induced substance(gene name synonym)	psi-mi:cos12_yeast(display_long)|uniprotkb:COS12(gene name)|psi-mi:COS12(display_short)|uniprotkb:NRC380(orf name)|uniprotkb:YGL263W(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11533028|imex:IM-24995-1118	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157613(gene)|ensembl:ENST00000621158(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0070278"(extracellular matrix constituent secretion)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029805|mint:Q96BA8|reactome:R-HSA-8874211|refseq:NP_443086.1|entrezgene/locuslink:90993(identity)	sgd:S000003232|refseq:NP_011251.1|dip:DIP-5034N|mint:P53053|ensemblfungi:YGL263W(gene)|ensemblfungi:YGL263W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005768"(endosome)|go:"GO:0016021"(integral component of membrane)|go:"GO:0043328"(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|interpro:IPR001142(Yeast membrane protein DUP)|sgd:YGL263W(identity)	-	comment:mint|function:"Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE"	crc64:52F58F4E400CA596	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:sMWUFmBeBBCO+T0Y2CuB/un1lBg9606	rogid:SqJH5ysFjpteLzoBp61CbATkXt8559292	intact-crc:23075904F3B3A9F3|rigid:IuS4cWZcVak54kXl6gI2iKw9N8U	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P53051	uniprotkb:P38646	intact:EBI-10464|ensemblfungi:YGR287C|uniprotkb:Q76CZ0|uniprotkb:D6VV64	intact:EBI-354932|ensembl:ENSP00000297185|uniprotkb:P30036|uniprotkb:P31932|uniprotkb:Q6GU03|uniprotkb:Q9BWB7|uniprotkb:B2RCM1|uniprotkb:Q1HB43|uniprotkb:Q53H23|uniprotkb:Q9UC56	psi-mi:malx3_yeast(display_long)|uniprotkb:YGR287C(locus name)|uniprotkb:IMA1(gene name)|psi-mi:IMA1(display_short)|uniprotkb:Alpha-glucosidase(gene name synonym)|uniprotkb:Isomaltase 1(gene name synonym)	psi-mi:grp75_human(display_long)|uniprotkb:HSPA9(gene name)|psi-mi:HSPA9(display_short)|uniprotkb:GRP75(gene name synonym)|uniprotkb:HSPA9B(gene name synonym)|uniprotkb:75 kDa glucose-regulated protein(gene name synonym)|uniprotkb:Heat shock 70 kDa protein 9(gene name synonym)|uniprotkb:Peptide-binding protein 74(gene name synonym)|uniprotkb:Mortalin(gene name synonym)|uniprotkb:mt-HSP70(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11533019|imex:IM-24995-1117	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003519|interpro:IPR006047(Glycosyl hydrolase, family 13, catalytic region)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|rcsb pdb:3A47|rcsb pdb:3A4A|rcsb pdb:3AJ7|ensemblfungi:YGR287C(gene)|ensemblfungi:YGR287C_mRNA(transcript)|go:"GO:0000025"(maltose catabolic process)|go:"GO:0004556"(alpha-amylase activity)|go:"GO:0004574"(oligo-1,6-glucosidase activity)|go:"GO:0004575"(sucrose alpha-glucosidase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005987"(sucrose catabolic process)|go:"GO:0009313"(oligosaccharide catabolic process)|go:"GO:0032450"(maltose alpha-glucosidase activity)|go:"GO:0033934"(glucan 1,4-alpha-maltotriohydrolase activity)|go:"GO:0046352"(disaccharide catabolic process)|rcsb pdb:3AXH|rcsb pdb:3AXI|refseq:NP_011803.3|interpro:IPR013780(Glycosyl hydrolase, family 13, all-beta)|reactome:R-SCE-352230|sgd:YGR287C(identity)	reactome:R-HSA-8949613|reactome:R-HSA-8950505|ensembl:ENSG00000113013(gene)|ensembl:ENST00000297185(transcript)|go:"GO:0001401"(SAM complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005925"(focal adhesion)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0007007"(inner mitochondrial membrane organization)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045646"(regulation of erythrocyte differentiation)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0140275"(MIB complex)|go:"GO:1902037"(negative regulation of hematopoietic stem cell differentiation)|go:"GO:1903707"(negative regulation of hemopoiesis)|interpro:IPR012725(Chaperone DnaK)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|go:"GO:0070062"(extracellular exosome)|interpro:IPR043129|mint:P38646|rcsb pdb:3N8E|rcsb pdb:4KBO|rcsb pdb:6NHK|rcsb pdb:6P2U|rcsb pdb:6PMT|reactome:R-HSA-1268020|reactome:R-HSA-3371453|refseq:NP_004125.3|dip:DIP-32936N|entrezgene/locuslink:3313(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:FhUpCS+n2c22jDt6Ai5m93wM3/w559292	rogid:xjSHeTKBb/lH1XNEEiMIjsM+XcE9606	intact-crc:C15CE37385EAAD37|rigid:Dkd2c8EWAskYKCAFjynK6eERRZM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P53038	uniprotkb:Q9UJV3-2	intact:EBI-19106|uniprotkb:D6VUN1|ensemblfungi:YGR099W	intact:EBI-10172526|ensembl:ENSP00000413976	psi-mi:tel2_yeast(display_long)|uniprotkb:YGR099W(locus name)|uniprotkb:TEL2(gene name)|psi-mi:TEL2(display_short)	psi-mi:q9ujv3-2(display_long)|uniprotkb:RING-type E3 ubiquitin transferase MID2(gene name synonym)|uniprotkb:FXY2(gene name synonym)|uniprotkb:Midin-2(gene name synonym)|uniprotkb:Midline defect 2(gene name synonym)|uniprotkb:Midline-2(gene name synonym)|uniprotkb:RING finger protein 60(gene name synonym)|uniprotkb:RNF60(gene name synonym)|uniprotkb:TRIM1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 1(gene name synonym)|uniprotkb:MID2(gene name)|psi-mi:MID2(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11533008|imex:IM-24995-1116	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003331|ensemblfungi:YGR099W(gene)|ensemblfungi:YGR099W_mRNA(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0005829"(cytosol)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0034502"(protein localization to chromosome)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0070209"(ASTRA complex)|interpro:IPR019337|interpro:IPR038528|rcsb pdb:3O4Z|refseq:NP_011613.3|dip:DIP-1245N|mint:P53038|sgd:YGR099W(identity)	intact:EBI-751983(isoform-parent)|uniprotkb:Q9UJV3-2(isoform-parent)|ensembl:ENSG00000080561(gene)|ensembl:ENST00000443968(transcript)|entrezgene/locuslink:11043(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:SZibPBili0M8YgHIwxf+sKkLk+M559292	rogid:/FJ+V2H7SaWon7caUWkEkmHFVxQ9606	intact-crc:04CE025866055AC1|rigid:six8sufYSUVN6LDhYbISxep+gaM	false	-	sufficient binding region:21-705	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P53202	uniprotkb:O43791	intact:EBI-23065|uniprotkb:D6VUE0|ensemblfungi:YGR003W	intact:EBI-743549|uniprotkb:Q53HJ1|uniprotkb:B2R6S3|uniprotkb:D3DTW7|ensembl:ENSP00000240327|ensembl:ENSP00000377001|ensembl:ENSP00000420908|ensembl:ENSP00000424119|ensembl:ENSP00000425905|ensembl:ENSP00000426986|ensembl:ENSP00000499562	psi-mi:cul3_yeast(display_long)|uniprotkb:CUL3(gene name)|psi-mi:CUL3(display_short)|uniprotkb:Cullin-B(gene name synonym)|uniprotkb:YGR003W(locus name)	psi-mi:spop_human(display_long)|uniprotkb:HIB homolog 1(gene name synonym)|uniprotkb:Roadkill homolog 1(gene name synonym)|uniprotkb:SPOP(gene name)|psi-mi:SPOP(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11533117|imex:IM-24995-1127	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011517.1|sgd:S000003235|dip:DIP-5506N|mint:P53202|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|ensemblfungi:YGR003W(gene)|ensemblfungi:YGR003W_mRNA(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|sgd:YGR003W(identity)	refseq:NP_001007227.1|refseq:NP_001007228.1|refseq:NP_001007229.1|refseq:NP_001007230.1|refseq:NP_001007231.1|refseq:NP_003554.1|refseq:XP_005257780.1|refseq:XP_005257781.1|ensembl:ENSG00000121067(gene)|ensembl:ENST00000347630(transcript)|ensembl:ENST00000393328(transcript)|ensembl:ENST00000503676(transcript)|ensembl:ENST00000504102(transcript)|ensembl:ENST00000509079(transcript)|ensembl:ENST00000514121(transcript)|ensembl:ENST00000665825(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0016607"(nuclear speck)|go:"GO:0030162"(regulation of proteolysis)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR034089|mint:O43791|rcsb pdb:2CR2|rcsb pdb:3HQH|rcsb pdb:3HQI|rcsb pdb:3HQL|rcsb pdb:3HQM|rcsb pdb:3HSV|rcsb pdb:3HTM|rcsb pdb:3HU6|rcsb pdb:3IVB|rcsb pdb:3IVQ|rcsb pdb:3IVV|rcsb pdb:4EOZ|rcsb pdb:4HS2|rcsb pdb:4J8Z|rcsb pdb:4O1V|rcsb pdb:6F8F|rcsb pdb:6F8G|rcsb pdb:6I41|rcsb pdb:6I5P|rcsb pdb:6I68|rcsb pdb:6I7A|rcsb pdb:7D3D|rcsb pdb:7LIN|rcsb pdb:7LIO|rcsb pdb:7LIP|rcsb pdb:7LIQ|reactome:R-HSA-5632684|go:"GO:0005634"(nucleus)|refseq:XP_016880693.1|dip:DIP-50517N|entrezgene/locuslink:8405(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:FvYjEpmLA9mF35UTi97nLZwp0eE559292	rogid:PC9ofpvk14xwTnnqT590/YRnx/49606	intact-crc:7A2EDA9519025780|rigid:zQaCFGgNUtTlFHC9ppqESiQzvUs	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P53176	uniprotkb:P63279	intact:EBI-6205|uniprotkb:D6VU89|ensemblfungi:YGL051W	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	psi-mi:mst27_yeast(display_long)|uniprotkb:MST27(gene name)|psi-mi:MST27(display_short)|uniprotkb:DUP2(gene name synonym)|uniprotkb:DUP240 protein MST27(gene name synonym)|uniprotkb:YGL051W(locus name)	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11533108|imex:IM-24995-1126	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003019|refseq:NP_011464.1|dip:DIP-1852N|ensemblfungi:YGL051W(gene)|ensemblfungi:YGL051W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030663"(COPI-coated vesicle membrane)|interpro:IPR001142(Yeast membrane protein DUP)|sgd:YGL051W(identity)	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N|entrezgene/locuslink:7329(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Vt2rgCK0Q+Ia3/1xU5hD7i+OCvg559292	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	intact-crc:B7474E645473DA0A|rigid:EDMg/R5oMoO1sTMuoldYSwH7pR4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P63279	uniprotkb:P53174	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	intact:EBI-6200|uniprotkb:D6VU88|ensemblfungi:YGL053W	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:prm8_yeast(display_long)|uniprotkb:PRM8(gene name)|psi-mi:PRM8(display_short)|uniprotkb:DUP1(gene name synonym)|uniprotkb:DUP240 protein PRM8(gene name synonym)|uniprotkb:Protein DUP1(gene name synonym)|uniprotkb:YGL053W(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11533099|imex:IM-24995-1125	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N|entrezgene/locuslink:7329(identity)	sgd:S000003021|refseq:NP_011462.1|dip:DIP-4067N|ensemblfungi:YGL053W(gene)|ensemblfungi:YGL053W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016192"(vesicle-mediated transport)|interpro:IPR001142(Yeast membrane protein DUP)|sgd:YGL053W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	rogid:rE9bUEB99azFFpZn5BA9/+Fhws8559292	intact-crc:F07A68A3211039F4|rigid:CV9iIx2ViQs/XU2hxbBckXZun4s	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96BA8	uniprotkb:P53173	intact:EBI-6942903|ensembl:ENSP00000481956|intact:MINT-268046|intact:MINT-8162577|uniprotkb:Q8N2D5|uniprotkb:Q96CP0	intact:EBI-6633|uniprotkb:D6VU87|ensemblfungi:YGL054C	psi-mi:cr3l1_human(display_long)|uniprotkb:CREB3L1(gene name)|psi-mi:CREB3L1(display_short)|uniprotkb:OASIS(gene name synonym)|uniprotkb:PSEC0238(orf name)|uniprotkb:Old astrocyte specifically-induced substance(gene name synonym)	psi-mi:erv14_yeast(display_long)|uniprotkb:ERV14(gene name)|psi-mi:ERV14(display_short)|uniprotkb:YGL054C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11533090|imex:IM-24995-1124	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157613(gene)|ensembl:ENST00000621158(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0070278"(extracellular matrix constituent secretion)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029805|mint:Q96BA8|reactome:R-HSA-8874211|refseq:NP_443086.1|entrezgene/locuslink:90993(identity)	refseq:NP_011461.1|sgd:S000003022|dip:DIP-5457N|ensemblfungi:YGL054C(gene)|ensemblfungi:YGL054C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007120"(axial cellular bud site selection)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0030437"(ascospore formation)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0071944"(cell periphery)|go:"GO:1902684"(negative regulation of receptor localization to synapse)|go:"GO:2000311"(regulation of AMPA receptor activity)|interpro:IPR003377(Cornichon)|interpro:IPR033466|sgd:YGL054C(identity)	-	comment:mint|function:"Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE"	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:sMWUFmBeBBCO+T0Y2CuB/un1lBg9606	rogid:KxwdOCXkpx+NMjtv4y+kU2ID99M559292	intact-crc:DA2128179CF09C4F|rigid:U6rII9M7DePFPuypuFYYswtZoiM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8N6L0	uniprotkb:P53142	intact:EBI-749265|uniprotkb:Q96MC3|ensembl:ENSP00000404220	intact:EBI-23899|uniprotkb:D6VU42|ensemblfungi:YGL104C	psi-mi:kash5_human(display_long)|uniprotkb:KASH5(gene name)|psi-mi:KASH5(display_short)|uniprotkb:CCDC155(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 155(gene name synonym)|uniprotkb:KASH domain-containing protein 5(gene name synonym)	psi-mi:vps73_yeast(display_long)|uniprotkb:VPS73(gene name)|psi-mi:VPS73(display_short)|uniprotkb:G3090(orf name)|uniprotkb:YGL104C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11533081|imex:IM-24995-1123	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_653289.3|ensembl:ENSG00000161609(gene)|ensembl:ENST00000447857(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034397"(telomere localization)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051225"(spindle assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0090172"(microtubule cytoskeleton organization involved in homologous chromosome segregation)|go:"GO:0090220"(chromosome localization to nuclear envelope involved in homologous chromosome segregation)|go:"GO:0090619"(meiotic spindle pole)|interpro:IPR011992(EF-Hand type)|interpro:IPR028168|interpro:IPR028170|interpro:IPR039508|mint:Q8N6L0|rcsb pdb:6R2I|rcsb pdb:6WMF|entrezgene/locuslink:147872(identity)	sgd:S000003072|refseq:NP_011411.3|reactome:R-SCE-5653890|dip:DIP-1727N|reactome:R-SCE-189200|reactome:R-SCE-196836|reactome:R-SCE-422356|reactome:R-SCE-6798695|reactome:R-SCE-8981373|ensemblfungi:YGL104C(gene)|ensemblfungi:YGL104C_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005739"(mitochondrion)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0055085"(transmembrane transport)|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR020846|interpro:IPR036259|sgd:YGL104C(identity)	-	-	crc64:D924D9112516450D	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Wl9L7AcvDHCZuKjYLn8QgGIbZTc9606	rogid:zkQIzKo7WxqNdwmETnOcsziImGk559292	intact-crc:23ADEA5BC7B22CD8|rigid:g0C5VCuajHxAAuy2R40a/94nheI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9H0B3-3	uniprotkb:P53141	intact:EBI-11533070	intact:EBI-10988|ensemblfungi:YGL106W|uniprotkb:D6VU40	psi-mi:q9h0b3-3(display_long)|uniprotkb:IQCN(gene name)|psi-mi:IQCN(display_short)|uniprotkb:KIAA1683(gene name synonym)	psi-mi:mlc1_yeast(display_long)|uniprotkb:G3080(orf name)|uniprotkb:MLC1(gene name)|psi-mi:MLC1(display_short)|uniprotkb:YGL106W(locus name)|uniprotkb:Myosin-2 light chain(gene name synonym)|uniprotkb:Calmodulin-like myosin light chain MLC1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11533068|imex:IM-24995-1122	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-745878(isoform-parent)|entrezgene/locuslink:80726(identity)	ensemblfungi:YGL106W(gene)|ensemblfungi:YGL106W_mRNA(transcript)|go:"GO:0000142"(cellular bud neck contractile ring)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005934"(cellular bud tip)|go:"GO:0006903"(vesicle targeting)|go:"GO:0016460"(myosin II complex)|go:"GO:0030427"(site of polarized growth)|go:"GO:0031489"(myosin V binding)|go:"GO:0031982"(vesicle)|go:"GO:0032038"(myosin II heavy chain binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0120155"(MIH complex)|go:"GO:1903476"(protein localization to cell division site involved in mitotic actomyosin contractile ring assembly)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|rcsb pdb:1M45|rcsb pdb:1M46|rcsb pdb:1N2D|rcsb pdb:2FCD|rcsb pdb:2FCE|reactome:R-SCE-5627123|go:"GO:0005935"(cellular bud neck)|refseq:NP_011409.1|sgd:S000003074|mint:P53141|dip:DIP-5576N|sgd:YGL106W(identity)	-	-	crc64:D7508123C101E4A6	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:oC4OG+AsWyQjmj2DKSPcLkrGYb89606	rogid:eC7nuA9RcHvmBgTFHG73tBQWfIY559292	intact-crc:D13DE1DA88812BCC|rigid:jOXjZZKV7oegFRCcMw2x0MI7Ig8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P43355	uniprotkb:P53140	intact:EBI-740978|ensembl:ENSP00000349085|uniprotkb:O00346|uniprotkb:B2RC81	intact:EBI-23904|uniprotkb:Q66RA9|uniprotkb:D6VU39|ensemblfungi:YGL107C	psi-mi:maga1_human(display_long)|uniprotkb:MAGE-1 antigen(gene name synonym)|uniprotkb:Antigen MZ2-E(gene name synonym)|uniprotkb:Cancer/testis antigen 1.1(gene name synonym)|uniprotkb:MAGEA1(gene name)|psi-mi:MAGEA1(display_short)|uniprotkb:MAGE1(gene name synonym)|uniprotkb:MAGE1A(gene name synonym)	psi-mi:rmd9_yeast(display_long)|uniprotkb:YGL107C(locus name)|uniprotkb:G3075(orf name)|uniprotkb:RMD9(gene name)|psi-mi:RMD9(display_short)|uniprotkb:Required for meiotic nuclear division protein 9(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11533059|imex:IM-24995-1121	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004979.3|ensembl:ENSG00000198681(gene)|ensembl:ENST00000356661(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|interpro:IPR002190(MAGE protein)|interpro:IPR021072|interpro:IPR030093|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|rcsb pdb:1W72|rcsb pdb:3BO8|dip:DIP-54794N|entrezgene/locuslink:4100(identity)	sgd:S000003075|refseq:NP_011408.1|interpro:IPR011990(Tetratricopeptide-like helical)|ensemblfungi:YGL107C(gene)|ensemblfungi:YGL107C_mRNA(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006413"(translational initiation)|go:"GO:0009060"(aerobic respiration)|go:"GO:0030435"(sporulation resulting in formation of a cellular spore)|go:"GO:0031314"(extrinsic component of mitochondrial inner membrane)|go:"GO:0043488"(regulation of mRNA stability)|rcsb pdb:7A9W|rcsb pdb:7A9X|sgd:YGL107C(identity)	-	crc64:544EEB1F9F4E9D33	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:6XW3mnTNM3yvOtXmiFbU8Uz3hjA9606	rogid:iO06ej1OrtaTNHBwQQFnMVZ1r1g559292	intact-crc:729FEAA4D7B031B7|rigid:5UBKUn8pyW5c8uX9ViH3Y8IOGZQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P53243	uniprotkb:P63279	intact:EBI-23197|uniprotkb:D6VUK1|ensemblfungi:YGR067C	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	psi-mi:yg2a_yeast(display_long)|uniprotkb:YGR067C(locus name)	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11533171|imex:IM-24995-1133	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003299|refseq:NP_011581.4|dip:DIP-2819N|mint:P53243|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|ensemblfungi:YGR067C(gene)|ensemblfungi:YGR067C_mRNA(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|sgd:YGR067C(identity)	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N|entrezgene/locuslink:7329(identity)	-	crc64:BB936C265B7B263F	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:/qkApijbHr7FKeeSJZ6IczHMf28559292	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	intact-crc:41112AFF41EFFC88|rigid:/jZIwuU3SbqWcHtgYxohgylsdM8	false	sufficient binding region:1-794	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9Y371	uniprotkb:P53218	intact:EBI-2623095|uniprotkb:Q9H3Z0|uniprotkb:Q9NYA9|uniprotkb:Q9NR47|uniprotkb:Q5H8U5|ensembl:ENSP00000473267|uniprotkb:B4E182	intact:EBI-13662|uniprotkb:D6VUG5|ensemblfungi:YGR030C	psi-mi:shlb1_human(display_long)|uniprotkb:KIAA0491(gene name synonym)|uniprotkb:Bax-interacting factor 1(gene name synonym)|uniprotkb:SH3 domain-containing GRB2-like protein B1(gene name synonym)|uniprotkb:CGI-61(orf name)|uniprotkb:SH3GLB1(gene name)|psi-mi:SH3GLB1(display_short)	psi-mi:pop6_yeast(display_long)|uniprotkb:POP6(gene name)|psi-mi:POP6(display_short)|uniprotkb:RNA-processing protein POP6(gene name synonym)|uniprotkb:RNases P/MRP 18.2 kDa subunit(gene name synonym)|uniprotkb:YGR030C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11533162|imex:IM-24995-1132	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001193580.1|refseq:NP_001193581.1|refseq:NP_057093.1|go:"GO:0030496"(midbody)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032801"(receptor catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0048102"(autophagic cell death)|go:"GO:0090148"(membrane fission)|go:"GO:1903527"(positive regulation of membrane tubulation)|go:"GO:1903778"(protein localization to vacuolar membrane)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|go:"GO:2000786"(positive regulation of autophagosome assembly)|interpro:IPR001452(Src homology-3)|interpro:IPR004148(BAR)|interpro:IPR027267|interpro:IPR028503|interpro:IPR035695|interpro:IPR036028|mint:Q9Y371|rcsb pdb:6UP6|rcsb pdb:6UPN|ensembl:ENSG00000097033(gene)|ensembl:ENST00000370558(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0006915"(apoptotic process)|go:"GO:0008289"(lipid binding)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016241"(regulation of macroautophagy)|refseq:NP_001193582.1|dip:DIP-41970N|entrezgene/locuslink:51100(identity)	refseq:NP_011544.1|sgd:S000003262|ensemblfungi:YGR030C(gene)|ensemblfungi:YGR030C_mRNA(transcript)|go:"GO:0000172"(ribonuclease MRP complex)|go:"GO:0000294"(nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay)|go:"GO:0003723"(RNA binding)|go:"GO:0004526"(ribonuclease P activity)|go:"GO:0005634"(nucleus)|go:"GO:0005655"(nucleolar ribonuclease P complex)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0008033"(tRNA processing)|go:"GO:0034965"(intronic box C/D RNA processing)|go:"GO:0042134"(rRNA primary transcript binding)|interpro:IPR002775(Alba, DNA/RNA-binding protein)|rcsb pdb:3IAB|rcsb pdb:6AGB|rcsb pdb:6AH3|rcsb pdb:6W6V|rcsb pdb:7C79|rcsb pdb:7C7A|mint:P53218|dip:DIP-6775N|sgd:YGR030C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:HSs455W45ciZL56fJSPOIvfhUIw9606	rogid:ynYc14nNfgwjbvWl8qgK5nKGOOo559292	intact-crc:D094E2BA63790926|rigid:eV2qszuzE22qQIQPSb168a36WRY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q969K4	uniprotkb:P53212	intact:EBI-7223971|uniprotkb:Q71MF1|uniprotkb:D3DNB0|intact:MINT-1193021|uniprotkb:Q6ZNU9|uniprotkb:Q96S63|uniprotkb:Q96S62|ensembl:ENSP00000232744	intact:EBI-23099|uniprotkb:D6VUF6|ensemblfungi:YGR021W	psi-mi:abtb1_human(display_long)|uniprotkb:ABTB1(gene name)|psi-mi:ABTB1(display_short)|uniprotkb:Elongation factor 1A-binding protein(gene name synonym)|uniprotkb:BPOZ(gene name synonym)|uniprotkb:PP2259(orf name)	psi-mi:yg1d_yeast(display_long)|uniprotkb:YGR021W(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11533153|imex:IM-24995-1131	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011511515.1|refseq:NP_115937.1|refseq:NP_742024.1|ensembl:ENSG00000114626(gene)|ensembl:ENST00000232744(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR020683|interpro:IPR036770|interpro:IPR044515|refseq:XP_016862776.1|entrezgene/locuslink:80325(identity)	refseq:NP_011535.1|sgd:S000003253|dip:DIP-6261N|mint:P53212|ensemblfungi:YGR021W(gene)|ensemblfungi:YGR021W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|interpro:IPR002876(Protein of unknown function DUF28)|interpro:IPR017856(Integrase, N-terminal zinc-binding domain-like)|interpro:IPR026564|interpro:IPR029072|sgd:YGR021W(identity)	-	comment:mint|comment:homomint|function:May act as a mediator of the PTEN growth-suppressive signaling pathway. May play a role in developmental processes	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:uWEJ/hAJBiKef/EJSNxP4OsXloM9606	rogid:/lU8xaIM/O6RTUPSlVUuReKFU5E559292	intact-crc:47B5069C5F7426FF|rigid:Wf1QdDYuUkCLAMcjXza8p6ERQG4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P53202	uniprotkb:Q9H898-2	intact:EBI-23065|uniprotkb:D6VUE0|ensemblfungi:YGR003W	intact:EBI-11529334|ensembl:ENSP00000319785	psi-mi:cul3_yeast(display_long)|uniprotkb:CUL3(gene name)|psi-mi:CUL3(display_short)|uniprotkb:Cullin-B(gene name synonym)|uniprotkb:YGR003W(locus name)	psi-mi:q9h898-2(display_long)|uniprotkb:ZMAT4(gene name)|psi-mi:ZMAT4(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11533144|imex:IM-24995-1130	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011517.1|sgd:S000003235|dip:DIP-5506N|mint:P53202|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|ensemblfungi:YGR003W(gene)|ensemblfungi:YGR003W_mRNA(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|sgd:YGR003W(identity)	ensembl:ENSG00000165061(gene)|ensembl:ENST00000315769(transcript)|intact:EBI-2548542(isoform-parent)|uniprotkb:Q9H898-2(isoform-parent)|entrezgene/locuslink:79698(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:FvYjEpmLA9mF35UTi97nLZwp0eE559292	rogid:LOS8TGoD/X97NtzSXSQ3uppdS6s9606	intact-crc:F0A1F0AE970D40C4|rigid:vDYwV4mPVgbNuC6HBYVnBl6io+E	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P53202	uniprotkb:Q96IK5	intact:EBI-23065|uniprotkb:D6VUE0|ensemblfungi:YGR003W	intact:EBI-2548508|ensembl:ENSP00000282570|uniprotkb:Q9H826|uniprotkb:Q9H8V7|uniprotkb:Q9H927	psi-mi:cul3_yeast(display_long)|uniprotkb:CUL3(gene name)|psi-mi:CUL3(display_short)|uniprotkb:Cullin-B(gene name synonym)|uniprotkb:YGR003W(locus name)	psi-mi:gmcl1_human(display_long)|uniprotkb:GMCL1(gene name)|psi-mi:GMCL1(display_short)|uniprotkb:GCL(gene name synonym)|uniprotkb:BTBD13(gene name synonym)|uniprotkb:SPATA29(gene name synonym)|uniprotkb:Spermatogenesis-associated protein 29(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11533135|imex:IM-24995-1129	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011517.1|sgd:S000003235|dip:DIP-5506N|mint:P53202|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|ensemblfungi:YGR003W(gene)|ensemblfungi:YGR003W_mRNA(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|sgd:YGR003W(identity)	ensembl:ENSG00000087338(gene)|ensembl:ENST00000282570(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0007281"(germ cell development)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016363"(nuclear matrix)|go:"GO:0042802"(identical protein binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR043380|refseq:NP_848526.1|entrezgene/locuslink:64395(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:FvYjEpmLA9mF35UTi97nLZwp0eE559292	rogid:ED8yqySVu7BWxpw3DUSNBZSQWrk9606	intact-crc:4A4DE5074A1C0D2C|rigid:kjnuALvK/s4J4YRNLcNbpMJrLbA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O95198	uniprotkb:P53202	intact:EBI-746999|uniprotkb:B2RD18|uniprotkb:Q8N484|uniprotkb:Q8TBH5|uniprotkb:A6NCM7|uniprotkb:B4DFH7|uniprotkb:F5H6M3|ensembl:ENSP00000226725	intact:EBI-23065|uniprotkb:D6VUE0|ensemblfungi:YGR003W	psi-mi:klhl2_human(display_long)|uniprotkb:Actin-binding protein Mayven(gene name synonym)|uniprotkb:KLHL2(gene name)|psi-mi:KLHL2(display_short)	psi-mi:cul3_yeast(display_long)|uniprotkb:CUL3(gene name)|psi-mi:CUL3(display_short)|uniprotkb:Cullin-B(gene name synonym)|uniprotkb:YGR003W(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11533126|imex:IM-24995-1128	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001154993.1|refseq:NP_001154994.1|refseq:NP_009177.3|refseq:NP_001317952.1|refseq:NP_001317953.1|refseq:XP_016863165.1|ensembl:ENSG00000109466(gene)|ensembl:ENST00000226725(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030027"(lamellipodium)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR017096(Kelch-like protein, gigaxonin)|interpro:IPR044072|mint:O95198|rcsb pdb:2XN4|rcsb pdb:4CHB|reactome:R-HSA-8951664|reactome:R-HSA-983168|go:"GO:0042802"(identical protein binding)|entrezgene/locuslink:11275(identity)	refseq:NP_011517.1|sgd:S000003235|dip:DIP-5506N|mint:P53202|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|ensemblfungi:YGR003W(gene)|ensemblfungi:YGR003W_mRNA(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|sgd:YGR003W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:tFegR2lJZccRqs4qUjdT3PNjNnk9606	rogid:FvYjEpmLA9mF35UTi97nLZwp0eE559292	intact-crc:6E122FA116794931|rigid:4KFd6cGaEu7kzWvz7zzXloqu8ak	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q969F0	uniprotkb:P53262	intact:EBI-743099|ensembl:ENSP00000359375	intact:EBI-2061527|uniprotkb:D6VUN8|ensemblfungi:YGR106C	psi-mi:fate1_human(display_long)|uniprotkb:Tumor antigen BJ-HCC-2(gene name synonym)|uniprotkb:Cancer/testis antigen 43(gene name synonym)|uniprotkb:FATE1(gene name)|psi-mi:FATE1(display_short)|uniprotkb:FATE(gene name synonym)	psi-mi:voa1_yeast(display_long)|uniprotkb:YGR106C(locus name)|uniprotkb:VOA1(gene name)|psi-mi:VOA1(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11533224|imex:IM-24995-1138	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_149076.1|ensembl:ENSG00000147378(gene)|ensembl:ENST00000370350(transcript)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|go:"GO:0051562"(negative regulation of mitochondrial calcium ion concentration)|interpro:IPR039153|interpro:IPR039433|mint:Q969F0|entrezgene/locuslink:89885(identity)	sgd:S000003338|refseq:NP_011620.1|mint:P53262|ensemblfungi:YGR106C(gene)|ensemblfungi:YGR106C_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034622"|rcsb pdb:6C6L|rcsb pdb:6M0R|rcsb pdb:6M0S|rcsb pdb:6O7T|rcsb pdb:6O7U|rcsb pdb:6O7V|rcsb pdb:6O7W|rcsb pdb:6O7X|rcsb pdb:6PE4|rcsb pdb:6PE5|sgd:YGR106C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Nm1N6lO92MHr5rIKC007oouF5RE9606	rogid:lKLIonttSEX36IQaIKlzxS/Cdxg559292	intact-crc:24E5575D07BCE54E|rigid:TrqFIPTlPqsUo/Q5JllfF0BXvLI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q2TAC2-2	uniprotkb:P53255	intact:EBI-10961624|ensembl:ENSP00000376154	intact:EBI-23234|uniprotkb:D6VUM5|ensemblfungi:YGR093W	psi-mi:q2tac2-2(display_long)|uniprotkb:CCDC57(gene name)|psi-mi:CCDC57(display_short)	psi-mi:drn1_yeast(display_long)|uniprotkb:YGR093W(locus name)|uniprotkb:DRN1(gene name)|psi-mi:DRN1(display_short)|uniprotkb:Debranching enzyme-associated ribonuclease 1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11533215|imex:IM-24995-1137	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000176155(gene)|ensembl:ENST00000392343(transcript)|uniprotkb:Q2TAC2-2(isoform-parent)|intact:EBI-2808286(isoform-parent)|entrezgene/locuslink:284001(identity)	sgd:S000003325|interpro:IPR006768(Protein similar to CwfJ, C-terminal 1)|interpro:IPR006767(Protein similar to CwfJ, C-terminal 2)|refseq:NP_011607.3|mint:P53255|interpro:IPR040194|interpro:IPR036265|ensemblfungi:YGR093W(gene)|ensemblfungi:YGR093W_mRNA(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0061632"(RNA lariat debranching enzyme activator activity)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|sgd:YGR093W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:RWcF0hgb1geIY959JUKrLK13Jx09606	rogid:oQ6T+SDSiEw5VpFLQvV/N6pRszs559292	intact-crc:1D693AD85D3A33A4|rigid:yQ2+o04bLwn6oSc0s6yweZVglRA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P63279	uniprotkb:P53252	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	intact:EBI-23225|uniprotkb:D6VUL8|ensemblfungi:YGR086C	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:pil1_yeast(display_long)|uniprotkb:YGR086C(locus name)|uniprotkb:PIL1(gene name)|psi-mi:PIL1(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11533206|imex:IM-24995-1136	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N|entrezgene/locuslink:7329(identity)	sgd:S000003318|refseq:NP_011600.3|dip:DIP-4618N|mint:P53252|ensemblfungi:YGR086C(gene)|ensemblfungi:YGR086C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0005886"(plasma membrane)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006897"(endocytosis)|go:"GO:0008104"(protein localization)|go:"GO:0008289"(lipid binding)|go:"GO:0009408"(response to heat)|go:"GO:0032126"(eisosome)|go:"GO:0036286"(eisosome filament)|go:"GO:0070941"(eisosome assembly)|go:"GO:0071944"(cell periphery)|go:"GO:0097446"(protein localization to eisosome filament)|interpro:IPR027267|interpro:IPR028245|sgd:YGR086C(identity)	-	-	crc64:C86AE5ABB508EA03	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	rogid:OtBCHiFwxzPwPX5y1oMTFqlc1Po559292	intact-crc:BA82B8B6451ACB70|rigid:8zEfk4Ahxs5xtk9FgPDZWRHYZBM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P53243	uniprotkb:Q96S82	intact:EBI-23197|uniprotkb:D6VUK1|ensemblfungi:YGR067C	intact:EBI-348604|uniprotkb:Q96I03|ensembl:ENSP00000378518|ensembl:ENSP00000454828|ensembl:ENSP00000457703|ensembl:ENSP00000457708|ensembl:ENSP00000500164|ensembl:ENSP00000500266|ensembl:ENSP00000500442|ensembl:ENSP00000500520|ensembl:ENSP00000500882|ensembl:ENSP00000354883|uniprotkb:D3DW57	psi-mi:yg2a_yeast(display_long)|uniprotkb:YGR067C(locus name)	psi-mi:ubl7_human(display_long)|uniprotkb:Ubiquitin-like protein SB132(gene name synonym)|uniprotkb:Bone marrow stromal cell ubiquitin-like protein(gene name synonym)|uniprotkb:UBL7(gene name)|psi-mi:UBL7(display_short)|uniprotkb:BMSCUBP(gene name synonym)|uniprotkb:SB132(orf name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11533195|imex:IM-24995-1135	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003299|refseq:NP_011581.4|dip:DIP-2819N|mint:P53243|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|ensemblfungi:YGR067C(gene)|ensemblfungi:YGR067C_mRNA(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|sgd:YGR067C(identity)	refseq:NP_116296.1|refseq:NP_957717.1|ensembl:ENST00000361351(transcript)|ensembl:ENST00000395081(transcript)|ensembl:ENST00000564488(transcript)|ensembl:ENST00000565335(transcript)|ensembl:ENST00000567435(transcript)|ensembl:ENST00000673054(transcript)|ensembl:ENST00000673073(transcript)|ensembl:ENST00000673120(transcript)|ensembl:ENST00000673153(transcript)|ensembl:ENST00000673461(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR029071|rcsb pdb:2CWB|rcsb pdb:2DEN|ensembl:ENSG00000138629(gene)|ensembl:ENSG00000288408(gene)|refseq:NP_001273668.1|refseq:NP_001273669.1|refseq:NP_001273670.1|refseq:NP_001273671.1|entrezgene/locuslink:84993(identity)	-	crc64:BB936C265B7B263F	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:/qkApijbHr7FKeeSJZ6IczHMf28559292	rogid:4E0ErEIkP/AQb+OHRuOd5wbXU/s9606	intact-crc:3151C9718B2ADCB7|rigid:S8zvAGQgBgIYqHUo1UXlwXsgxy8	false	sufficient binding region:1-794	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8IUQ4-2	uniprotkb:P53243	intact:EBI-11522811|ensembl:ENSP00000349156	intact:EBI-23197|uniprotkb:D6VUK1|ensemblfungi:YGR067C	psi-mi:q8iuq4-2(display_long)|uniprotkb:SIAH1(gene name)|psi-mi:SIAH1(display_short)|uniprotkb:HUMSIAH(gene name synonym)|uniprotkb:Seven in absentia homolog 1(gene name synonym)|uniprotkb:Siah-1a(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase SIAH1(gene name synonym)	psi-mi:yg2a_yeast(display_long)|uniprotkb:YGR067C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11533182|imex:IM-24995-1134	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-747107(isoform-parent)|ensembl:ENSG00000196470(gene)|ensembl:ENST00000356721(transcript)|uniprotkb:Q8IUQ4-2(isoform-parent)|entrezgene/locuslink:6477(identity)	sgd:S000003299|refseq:NP_011581.4|dip:DIP-2819N|mint:P53243|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|ensemblfungi:YGR067C(gene)|ensemblfungi:YGR067C_mRNA(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|sgd:YGR067C(identity)	-	-	crc64:BB936C265B7B263F	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:M4q06jVbWuq1mGMXvtuFBaMEgZM9606	rogid:/qkApijbHr7FKeeSJZ6IczHMf28559292	intact-crc:7383E21345D90817|rigid:trRKgSdgdVLhq8Xh70Mscr/zkUM	false	sufficient binding region:32-313	sufficient binding region:1-794	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P53286	uniprotkb:P63279	intact:EBI-3796|uniprotkb:D6VUS2|ensemblfungi:YGR142W	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	psi-mi:btn2_yeast(display_long)|uniprotkb:YGR142W(locus name)|uniprotkb:BTN2(gene name)|psi-mi:BTN2(display_short)|uniprotkb:Batten disease protein 2(gene name synonym)	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11533278|imex:IM-24995-1144	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003374|refseq:NP_011658.3|dip:DIP-5534N|mint:P53286|ensemblfungi:YGR142W(gene)|ensemblfungi:YGR142W_mRNA(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005634"(nucleus)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006865"(amino acid transport)|go:"GO:0006885"(regulation of pH)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051087"(chaperone binding)|go:"GO:0140311"(protein sequestering activity)|sgd:YGR142W(identity)	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N|entrezgene/locuslink:7329(identity)	-	crc64:E7AE1EB1E3612F3E	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Cu27xkwGMNyS4zLvUaG1UeH2mE0559292	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	intact-crc:EDF1EEEE61BB695E|rigid:gK6tt7o2LgaREYUhL/GCgAqYw1o	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P53286	uniprotkb:P14373	intact:EBI-3796|uniprotkb:D6VUS2|ensemblfungi:YGR142W	intact:EBI-719493|uniprotkb:A2BE15|uniprotkb:Q5RJA8|uniprotkb:Q5ST26|uniprotkb:Q6LA73|uniprotkb:Q6NXR9|uniprotkb:Q9BZY6|uniprotkb:Q9UJL3|ensembl:ENSP00000383555|ensembl:ENSP00000392787|ensembl:ENSP00000405229|ensembl:ENSP00000414793|ensembl:ENSP00000366404	psi-mi:btn2_yeast(display_long)|uniprotkb:YGR142W(locus name)|uniprotkb:BTN2(gene name)|psi-mi:BTN2(display_short)|uniprotkb:Batten disease protein 2(gene name synonym)	psi-mi:tri27_human(display_long)|uniprotkb:TRIM27(gene name)|psi-mi:TRIM27(display_short)|uniprotkb:RNF76(gene name synonym)|uniprotkb:RFP(gene name synonym)|uniprotkb:Ret finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 27(gene name synonym)|uniprotkb:RING finger protein 76(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM27(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11533269|imex:IM-24995-1143	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003374|refseq:NP_011658.3|dip:DIP-5534N|mint:P53286|ensemblfungi:YGR142W(gene)|ensemblfungi:YGR142W_mRNA(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005634"(nucleus)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006865"(amino acid transport)|go:"GO:0006885"(regulation of pH)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051087"(chaperone binding)|go:"GO:0140311"(protein sequestering activity)|sgd:YGR142W(identity)	refseq:NP_006501.1|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0090281"(negative regulation of calcium ion import)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR020457|interpro:IPR035791|interpro:IPR043136|mint:P14373|reactome:R-HSA-3232142|reactome:R-HSA-9635465|reactome:R-HSA-8948751|ensembl:ENSG00000204713(gene)|ensembl:ENSG00000215641(gene)|ensembl:ENSG00000229006(gene)|ensembl:ENSG00000234495(gene)|ensembl:ENSG00000237071(gene)|ensembl:ENST00000377199(transcript)|ensembl:ENST00000400720(transcript)|ensembl:ENST00000431123(transcript)|ensembl:ENST00000435528(transcript)|ensembl:ENST00000437160(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001650"(fibrillar center)|go:"GO:0002820"(negative regulation of adaptive immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|entrezgene/locuslink:5987(identity)	-	crc64:E7AE1EB1E3612F3E	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Cu27xkwGMNyS4zLvUaG1UeH2mE0559292	rogid:dsfH5OUghD8KSaTz1SFw9OYVTK49606	intact-crc:ACDCB757A80A4FD7|rigid:EeK2OKS7QHYLx/SeETjhKZnWZCY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P53286	uniprotkb:A0A0C4DGF1	intact:EBI-3796|uniprotkb:D6VUS2|ensemblfungi:YGR142W	intact:EBI-10188476|ensembl:ENSP00000433657	psi-mi:btn2_yeast(display_long)|uniprotkb:YGR142W(locus name)|uniprotkb:BTN2(gene name)|psi-mi:BTN2(display_short)|uniprotkb:Batten disease protein 2(gene name synonym)	psi-mi:a0a0c4dgf1_human(display_long)|uniprotkb:ZBTB32(gene name)|psi-mi:ZBTB32(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11533260|imex:IM-24995-1142	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003374|refseq:NP_011658.3|dip:DIP-5534N|mint:P53286|ensemblfungi:YGR142W(gene)|ensemblfungi:YGR142W_mRNA(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005634"(nucleus)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006865"(amino acid transport)|go:"GO:0006885"(regulation of pH)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051087"(chaperone binding)|go:"GO:0140311"(protein sequestering activity)|sgd:YGR142W(identity)	interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|ensembl:ENSG00000011590(gene)|ensembl:ENST00000481182(transcript)|go:"GO:0042802"(identical protein binding)|entrezgene/locuslink:27033(identity)	-	crc64:E7AE1EB1E3612F3E	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Cu27xkwGMNyS4zLvUaG1UeH2mE0559292	rogid:w3k7YT4kw/T+Xi5YBqGHSpHtwMM9606	intact-crc:4BEAFAE0D61B85D9|rigid:02tTGbPh1uOnYhZK9iXwT9tfYk4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8N5R6	uniprotkb:P53286	intact:EBI-740841|intact:EBI-953781|uniprotkb:B3KQ49|uniprotkb:A8K3U4|uniprotkb:A8MPQ6|uniprotkb:A8MV61|uniprotkb:A8MVU9|uniprotkb:Q9H5Q6|uniprotkb:Q8TAX6|intact:EBI-2320546|intact:EBI-11522976	intact:EBI-3796|uniprotkb:D6VUS2|ensemblfungi:YGR142W	psi-mi:ccd33_human(display_long)|uniprotkb:CCDC33(gene name)|psi-mi:CCDC33(display_short)|uniprotkb:Cancer/testis antigen 61(gene name synonym)	psi-mi:btn2_yeast(display_long)|uniprotkb:YGR142W(locus name)|uniprotkb:BTN2(gene name)|psi-mi:BTN2(display_short)|uniprotkb:Batten disease protein 2(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11533251|imex:IM-24995-1141	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_079331.3|interpro:IPR000008(C2 calcium-dependent membrane targeting)|go:"GO:0005777"(peroxisome)|refseq:NP_001274110.1|refseq:NP_877592.2|mint:Q8N5R6|interpro:IPR035892|interpro:IPR039889|entrezgene/locuslink:80125(identity)	sgd:S000003374|refseq:NP_011658.3|dip:DIP-5534N|mint:P53286|ensemblfungi:YGR142W(gene)|ensemblfungi:YGR142W_mRNA(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005634"(nucleus)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006865"(amino acid transport)|go:"GO:0006885"(regulation of pH)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051087"(chaperone binding)|go:"GO:0140311"(protein sequestering activity)|sgd:YGR142W(identity)	-	-	crc64:E7AE1EB1E3612F3E	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2021/11/30	rogid:eEIn7pQyfdHWx8TeLJpYy0i/gww9606	rogid:Cu27xkwGMNyS4zLvUaG1UeH2mE0559292	intact-crc:66982E0B1918E307|rigid:JS2g2RcnPmP5C7qNkAk1VjyMSKE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P53278	uniprotkb:P61289	intact:EBI-23314|uniprotkb:D6VUR2|ensemblfungi:YGR130C	intact:EBI-355546|uniprotkb:O35563|uniprotkb:P97373|uniprotkb:Q12920|uniprotkb:Q13172|uniprotkb:Q9BQD9|uniprotkb:A8K9A3|ensembl:ENSP00000466794	psi-mi:yg3a_yeast(display_long)|uniprotkb:YGR130C(locus name)	psi-mi:psme3_human(display_long)|uniprotkb:PSME3(gene name)|psi-mi:PSME3(display_short)|uniprotkb:Proteasome activator 28 subunit gamma(gene name synonym)|uniprotkb:Activator of multicatalytic protease subunit 3(gene name synonym)|uniprotkb:11S regulator complex subunit gamma(gene name synonym)|uniprotkb:Ki nuclear autoantigen(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11533242|imex:IM-24995-1140	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011646.1|sgd:S000003362|dip:DIP-3006N|mint:P53278|ensemblfungi:YGR130C(gene)|ensemblfungi:YGR130C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0032126"(eisosome)|sgd:YGR130C(identity)	refseq:NP_005780.2|refseq:NP_789839.1|ensembl:ENSG00000131467(gene)|ensembl:ENST00000590720(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0008537"(proteasome activator complex)|go:"GO:0010950"(positive regulation of endopeptidase activity)|go:"GO:0016020"(membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0061133"(endopeptidase activator activity)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0097371"(MDM2/MDM4 family protein binding)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR003185(Proteasome activator pa28, REG alpha subunit)|interpro:IPR003186(Proteasome activator pa28, REG beta subunit)|interpro:IPR009077(Proteasome activator pa28, REG alpha/beta subunit)|interpro:IPR036252|interpro:IPR036996|interpro:IPR036997|mint:P61289|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|entrezgene/locuslink:10197(identity)	-	crc64:D482327C9274C026	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:iTa1C3VXvI8QteEEgkfjQDp9gvY559292	rogid:6EQY2Kj3Juf++m4eBDzPWMgbC2k9606	intact-crc:0CB7D0850E5EF5AB|rigid:DC1j0vegFjPWtc6Trafxcf34fGE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O43791	uniprotkb:P53278	intact:EBI-743549|uniprotkb:Q53HJ1|uniprotkb:B2R6S3|uniprotkb:D3DTW7|ensembl:ENSP00000240327|ensembl:ENSP00000377001|ensembl:ENSP00000420908|ensembl:ENSP00000424119|ensembl:ENSP00000425905|ensembl:ENSP00000426986|ensembl:ENSP00000499562	intact:EBI-23314|uniprotkb:D6VUR2|ensemblfungi:YGR130C	psi-mi:spop_human(display_long)|uniprotkb:HIB homolog 1(gene name synonym)|uniprotkb:Roadkill homolog 1(gene name synonym)|uniprotkb:SPOP(gene name)|psi-mi:SPOP(display_short)	psi-mi:yg3a_yeast(display_long)|uniprotkb:YGR130C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11533233|imex:IM-24995-1139	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001007227.1|refseq:NP_001007228.1|refseq:NP_001007229.1|refseq:NP_001007230.1|refseq:NP_001007231.1|refseq:NP_003554.1|refseq:XP_005257780.1|refseq:XP_005257781.1|ensembl:ENSG00000121067(gene)|ensembl:ENST00000347630(transcript)|ensembl:ENST00000393328(transcript)|ensembl:ENST00000503676(transcript)|ensembl:ENST00000504102(transcript)|ensembl:ENST00000509079(transcript)|ensembl:ENST00000514121(transcript)|ensembl:ENST00000665825(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0016607"(nuclear speck)|go:"GO:0030162"(regulation of proteolysis)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR034089|mint:O43791|rcsb pdb:2CR2|rcsb pdb:3HQH|rcsb pdb:3HQI|rcsb pdb:3HQL|rcsb pdb:3HQM|rcsb pdb:3HSV|rcsb pdb:3HTM|rcsb pdb:3HU6|rcsb pdb:3IVB|rcsb pdb:3IVQ|rcsb pdb:3IVV|rcsb pdb:4EOZ|rcsb pdb:4HS2|rcsb pdb:4J8Z|rcsb pdb:4O1V|rcsb pdb:6F8F|rcsb pdb:6F8G|rcsb pdb:6I41|rcsb pdb:6I5P|rcsb pdb:6I68|rcsb pdb:6I7A|rcsb pdb:7D3D|rcsb pdb:7LIN|rcsb pdb:7LIO|rcsb pdb:7LIP|rcsb pdb:7LIQ|reactome:R-HSA-5632684|go:"GO:0005634"(nucleus)|refseq:XP_016880693.1|dip:DIP-50517N|entrezgene/locuslink:8405(identity)	refseq:NP_011646.1|sgd:S000003362|dip:DIP-3006N|mint:P53278|ensemblfungi:YGR130C(gene)|ensemblfungi:YGR130C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0032126"(eisosome)|sgd:YGR130C(identity)	-	-	crc64:D482327C9274C026	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:PC9ofpvk14xwTnnqT590/YRnx/49606	rogid:iTa1C3VXvI8QteEEgkfjQDp9gvY559292	intact-crc:FD37B02F9EE3E2BD|rigid:XtueZT1ahsSmPIYF7JfJWCuO+cQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q6P1W5	uniprotkb:P53286	intact:EBI-946029|uniprotkb:B3KVT1|uniprotkb:Q96IC8|ensembl:ENSP00000435634|uniprotkb:D3DPR3|uniprotkb:E9PJ76	intact:EBI-3796|uniprotkb:D6VUS2|ensemblfungi:YGR142W	psi-mi:ca094_human(display_long)|uniprotkb:C1orf94(gene name)|psi-mi:C1orf94(display_short)	psi-mi:btn2_yeast(display_long)|uniprotkb:YGR142W(locus name)|uniprotkb:BTN2(gene name)|psi-mi:BTN2(display_short)|uniprotkb:Batten disease protein 2(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11533338|imex:IM-24995-1150	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001128206.1|refseq:NP_116273.2|ensembl:ENSG00000142698(gene)|ensembl:ENST00000488417(transcript)|interpro:IPR031496|entrezgene/locuslink:84970(identity)	sgd:S000003374|refseq:NP_011658.3|dip:DIP-5534N|mint:P53286|ensemblfungi:YGR142W(gene)|ensemblfungi:YGR142W_mRNA(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005634"(nucleus)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006865"(amino acid transport)|go:"GO:0006885"(regulation of pH)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051087"(chaperone binding)|go:"GO:0140311"(protein sequestering activity)|sgd:YGR142W(identity)	-	-	crc64:E7AE1EB1E3612F3E	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:y1o4xWvTl2CBA1J7jsP7y8ZjLzM9606	rogid:Cu27xkwGMNyS4zLvUaG1UeH2mE0559292	intact-crc:B7C2B2C361F6B05F|rigid:rwo3wJUtUQCT6celj1ZqUnTbioI	false	sufficient binding region:191-598	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q6IBW4	uniprotkb:P53286	intact:EBI-2548296|ensembl:ENSP00000410088|uniprotkb:Q9BUT3|uniprotkb:Q9BVD1|uniprotkb:B7WPH1|uniprotkb:O43788|uniprotkb:Q13391|uniprotkb:Q96C14|uniprotkb:Q96GJ0|uniprotkb:Q9BQ71	intact:EBI-3796|uniprotkb:D6VUS2|ensemblfungi:YGR142W	psi-mi:cndh2_human(display_long)|uniprotkb:NCAPH2(gene name)|psi-mi:NCAPH2(display_short)|uniprotkb:CAPH2(gene name synonym)|uniprotkb:Non-SMC condensin II complex subunit H2(gene name synonym)|uniprotkb:Chromosome-associated protein H2(gene name synonym)|uniprotkb:Kleisin-beta(gene name synonym)	psi-mi:btn2_yeast(display_long)|uniprotkb:YGR142W(locus name)|uniprotkb:BTN2(gene name)|psi-mi:BTN2(display_short)|uniprotkb:Batten disease protein 2(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11533327|imex:IM-24995-1149	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000025770(gene)|ensembl:ENST00000420993(transcript)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000796"(condensin complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0010032"(meiotic chromosome condensation)|go:"GO:0016020"(membrane)|go:"GO:0030054"(cell junction)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0045171"(intercellular bridge)|go:"GO:0051306"(mitotic sister chromatid separation)|go:"GO:0051309"(female meiosis chromosome separation)|interpro:IPR009378(Protein of unknown function DUF1032)|interpro:IPR031719|interpro:IPR031737|interpro:IPR031739|mint:Q6IBW4|reactome:R-HSA-2299718|refseq:NP_001171940.1|refseq:NP_055366.3|refseq:NP_689512.2|dip:DIP-43901N|entrezgene/locuslink:29781(identity)	sgd:S000003374|refseq:NP_011658.3|dip:DIP-5534N|mint:P53286|ensemblfungi:YGR142W(gene)|ensemblfungi:YGR142W_mRNA(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005634"(nucleus)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006865"(amino acid transport)|go:"GO:0006885"(regulation of pH)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051087"(chaperone binding)|go:"GO:0140311"(protein sequestering activity)|sgd:YGR142W(identity)	-	-	crc64:E7AE1EB1E3612F3E	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:GTOZg0OoAHm+tj3C8/3sCGM+G5E9606	rogid:Cu27xkwGMNyS4zLvUaG1UeH2mE0559292	intact-crc:34B456B965516246|rigid:8Lov5MtCZxiAfmGnN71zLKWgNAk	false	sufficient binding region:150-605	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P53286	uniprotkb:Q5VWN6	intact:EBI-3796|uniprotkb:D6VUS2|ensemblfungi:YGR142W	intact:EBI-745958|uniprotkb:Q2YD91|uniprotkb:Q5VWN5|uniprotkb:Q6ZRQ8|uniprotkb:Q8IVG4|uniprotkb:Q9BUZ7|uniprotkb:Q9H5J9|uniprotkb:Q9H7A4|uniprotkb:Q9H996|uniprotkb:Q9NXA1|intact:EBI-28974916|ensembl:ENSP00000328426	psi-mi:btn2_yeast(display_long)|uniprotkb:YGR142W(locus name)|uniprotkb:BTN2(gene name)|psi-mi:BTN2(display_short)|uniprotkb:Batten disease protein 2(gene name synonym)	psi-mi:taso2_human(display_long)|uniprotkb:TASOR2(gene name)|psi-mi:TASOR2(display_short)|uniprotkb:C10orf18(gene name synonym)|uniprotkb:FAM208B(gene name synonym)|uniprotkb:KIAA2006(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11533316|imex:IM-24995-1148	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003374|refseq:NP_011658.3|dip:DIP-5534N|mint:P53286|ensemblfungi:YGR142W(gene)|ensemblfungi:YGR142W_mRNA(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005634"(nucleus)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006865"(amino acid transport)|go:"GO:0006885"(regulation of pH)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051087"(chaperone binding)|go:"GO:0140311"(protein sequestering activity)|sgd:YGR142W(identity)	refseq:NP_060252.4|ensembl:ENSP00000328426|refseq:XP_011517827.1|refseq:XP_016871852.1|refseq:XP_016871854.1|ensembl:ENSG00000108021(gene)|ensembl:ENST00000328090(transcript)|go:"GO:0005829"(cytosol)|interpro:IPR022168|interpro:IPR022188|mint:Q5VWN6|go:"GO:0005654"(nucleoplasm)|refseq:XP_005252532.1|refseq:XP_005252537.1|refseq:XP_005252538.1|refseq:XP_005252539.1|refseq:NP_001308712.1|refseq:NP_001308713.1|refseq:NP_001308714.1|entrezgene/locuslink:54906(identity)	-	crc64:E7AE1EB1E3612F3E	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Cu27xkwGMNyS4zLvUaG1UeH2mE0559292	rogid:mTRMzWB45dZojaB1ZrsaQRT48YQ9606	intact-crc:90EFE777BAC4F416|rigid:7+7MsobuGDkG6QcBDTEJk0uu9fc	false	-	sufficient binding region:1690-2430	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q5T124-6	uniprotkb:P53286	intact:EBI-11524408	intact:EBI-3796|uniprotkb:D6VUS2|ensemblfungi:YGR142W	psi-mi:q5t124-6(display_long)|uniprotkb:UBXN11(gene name)|psi-mi:UBXN11(display_short)|uniprotkb:Colorectal tumor-associated antigen COA-1(gene name synonym)|uniprotkb:SOC(gene name synonym)|uniprotkb:Socius(gene name synonym)|uniprotkb:UBX domain-containing protein 5(gene name synonym)|uniprotkb:UBXD5(gene name synonym)|uniprotkb:PP2243(orf name)	psi-mi:btn2_yeast(display_long)|uniprotkb:YGR142W(locus name)|uniprotkb:BTN2(gene name)|psi-mi:BTN2(display_short)|uniprotkb:Batten disease protein 2(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11533307|imex:IM-24995-1147	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-746004(isoform-parent)|uniprotkb:Q5T124-6(isoform-parent)|entrezgene/locuslink:91544(identity)	sgd:S000003374|refseq:NP_011658.3|dip:DIP-5534N|mint:P53286|ensemblfungi:YGR142W(gene)|ensemblfungi:YGR142W_mRNA(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005634"(nucleus)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006865"(amino acid transport)|go:"GO:0006885"(regulation of pH)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051087"(chaperone binding)|go:"GO:0140311"(protein sequestering activity)|sgd:YGR142W(identity)	-	-	crc64:E7AE1EB1E3612F3E	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:1YSjG/p2ihcjl4P8KdPCaX2HxiY9606	rogid:Cu27xkwGMNyS4zLvUaG1UeH2mE0559292	intact-crc:E93883C664FC0DE7|rigid:ja8+IzdWLG0ECQqfwNmkJEO2qik	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P53286	uniprotkb:Q53G59	intact:EBI-3796|uniprotkb:D6VUS2|ensemblfungi:YGR142W	intact:EBI-740929|ensembl:ENSP00000356230|uniprotkb:A6NEN8|uniprotkb:B7Z7B8|uniprotkb:Q9HBX5	psi-mi:btn2_yeast(display_long)|uniprotkb:YGR142W(locus name)|uniprotkb:BTN2(gene name)|psi-mi:BTN2(display_short)|uniprotkb:Batten disease protein 2(gene name synonym)	psi-mi:klh12_human(display_long)|uniprotkb:CUL3-interacting protein 1(gene name synonym)|uniprotkb:KLHL12(gene name)|psi-mi:KLHL12(display_short)|uniprotkb:C3IP1(gene name synonym)|uniprotkb:DKIR homolog(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11533298|imex:IM-24995-1146	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003374|refseq:NP_011658.3|dip:DIP-5534N|mint:P53286|ensemblfungi:YGR142W(gene)|ensemblfungi:YGR142W_mRNA(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005634"(nucleus)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006865"(amino acid transport)|go:"GO:0006885"(regulation of pH)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051087"(chaperone binding)|go:"GO:0140311"(protein sequestering activity)|sgd:YGR142W(identity)	go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048208"(COPII vesicle coating)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR017096(Kelch-like protein, gigaxonin)|mint:Q53G59|rcsb pdb:2VPJ|rcsb pdb:6TTK|rcsb pdb:6V7O|reactome:R-HSA-4641258|refseq:NP_067646.1|ensembl:ENSG00000117153(gene)|ensembl:ENST00000367261(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0014029"(neural crest formation)|go:"GO:0014032"(neural crest cell development)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0034451"(centriolar satellite)|refseq:NP_001289980.1|refseq:NP_001290038.1|entrezgene/locuslink:59349(identity)	-	crc64:E7AE1EB1E3612F3E	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Cu27xkwGMNyS4zLvUaG1UeH2mE0559292	rogid:C4I/Ys9vqNqfG61HsXRZhywP4vE9606	intact-crc:EA1938E6BC601F77|rigid:r2ZpBzJpduxdwbAVvF/LFDNgKak	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q13164	uniprotkb:P53286	intact:EBI-1213983|uniprotkb:Q16634|uniprotkb:Q59F50|uniprotkb:Q6QLU7|uniprotkb:Q7L4P4|uniprotkb:Q969G1|uniprotkb:Q96G51|intact:EBI-28979986|ensembl:ENSP00000311005|ensembl:ENSP00000378966|ensembl:ENSP00000378968	intact:EBI-3796|uniprotkb:D6VUS2|ensemblfungi:YGR142W	psi-mi:mk07_human(display_long)|uniprotkb:MAPK7(gene name)|psi-mi:MAPK7(display_short)|uniprotkb:BMK1(gene name synonym)|uniprotkb:ERK5(gene name synonym)|uniprotkb:PRKM7(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 5(gene name synonym)|uniprotkb:Big MAP kinase 1(gene name synonym)	psi-mi:btn2_yeast(display_long)|uniprotkb:YGR142W(locus name)|uniprotkb:BTN2(gene name)|psi-mi:BTN2(display_short)|uniprotkb:Batten disease protein 2(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11533287|imex:IM-24995-1145	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002740.2|refseq:NP_620601.1|refseq:NP_620602.2|refseq:NP_620603.2|ensembl:ENST00000299612|ensembl:ENSP00000299612|ensembl:ENSP00000311005|ensembl:ENSP00000378966|ensembl:ENSP00000378968|refseq:XP_011522259.1|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0036003"(positive regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0051019"(mitogen-activated protein kinase binding)|go:"GO:0051247"(positive regulation of protein metabolic process)|go:"GO:0051344"(negative regulation of cyclic-nucleotide phosphodiesterase activity)|go:"GO:0060761"(negative regulation of response to cytokine stimulus)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071499"(cellular response to laminar fluid shear stress)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1902176"(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:2000352"(negative regulation of endothelial cell apoptotic process)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q13164|rcsb pdb:2Q8Y|rcsb pdb:4B99|rcsb pdb:4IC7|rcsb pdb:4IC8|rcsb pdb:4ZSG|rcsb pdb:4ZSJ|rcsb pdb:4ZSL|rcsb pdb:5BYY|rcsb pdb:5BYZ|rcsb pdb:5O7I|rcsb pdb:6HKM|rcsb pdb:6HKN|reactome:R-HSA-198753|reactome:R-HSA-198765|reactome:R-HSA-202670|reactome:R-HSA-2559582|reactome:R-HSA-881907|reactome:R-HSA-8853659|ensembl:ENSG00000166484(gene)|ensembl:ENST00000308406(transcript)|ensembl:ENST00000395602(transcript)|ensembl:ENST00000395604(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0016605"(PML body)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0030154"(cell differentiation)|go:"GO:0034115"(negative regulation of heterotypic cell-cell adhesion)|entrezgene/locuslink:5598(identity)	sgd:S000003374|refseq:NP_011658.3|dip:DIP-5534N|mint:P53286|ensemblfungi:YGR142W(gene)|ensemblfungi:YGR142W_mRNA(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005634"(nucleus)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006865"(amino acid transport)|go:"GO:0006885"(regulation of pH)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051087"(chaperone binding)|go:"GO:0140311"(protein sequestering activity)|sgd:YGR142W(identity)	-	-	crc64:E7AE1EB1E3612F3E	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:dUTMnlgdjEkFhq0i6RmvpX5U7BM9606	rogid:Cu27xkwGMNyS4zLvUaG1UeH2mE0559292	intact-crc:29399BF63A5B9010|rigid:JEZNN4b3KaX3CQ1ZRZjBKbJOam0	false	sufficient binding region:140-816	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P53286	uniprotkb:Q8WV44	intact:EBI-3796|uniprotkb:D6VUS2|ensemblfungi:YGR142W	intact:EBI-725997|uniprotkb:Q5BKT0|uniprotkb:Q7L484|uniprotkb:Q96Q10|intact:EBI-1551110|uniprotkb:Q9BSL8|uniprotkb:B3KNJ6|uniprotkb:D3DWR9|ensembl:ENSP00000320869	psi-mi:btn2_yeast(display_long)|uniprotkb:YGR142W(locus name)|uniprotkb:BTN2(gene name)|psi-mi:BTN2(display_short)|uniprotkb:Batten disease protein 2(gene name synonym)	psi-mi:tri41_human(display_long)|uniprotkb:TRIM41(gene name)|psi-mi:TRIM41(display_short)|uniprotkb:RINCK(gene name synonym)|uniprotkb:Tripartite motif-containing protein 41(gene name synonym)|uniprotkb:RING finger-interacting protein with C kinase(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM41(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11533387|imex:IM-24995-1155	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003374|refseq:NP_011658.3|dip:DIP-5534N|mint:P53286|ensemblfungi:YGR142W(gene)|ensemblfungi:YGR142W_mRNA(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005634"(nucleus)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006865"(amino acid transport)|go:"GO:0006885"(regulation of pH)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051087"(chaperone binding)|go:"GO:0140311"(protein sequestering activity)|sgd:YGR142W(identity)	refseq:NP_291027.3|refseq:NP_963921.1|ensembl:ENSG00000146063(gene)|ensembl:ENST00000315073(transcript)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0042802"(identical protein binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071225"(cellular response to muramyl dipeptide)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR042828|interpro:IPR043136|mint:Q8WV44|rcsb pdb:2EGM|reactome:R-HSA-983168|entrezgene/locuslink:90933(identity)	-	crc64:E7AE1EB1E3612F3E	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Cu27xkwGMNyS4zLvUaG1UeH2mE0559292	rogid:BVqf0OHXPGsYe8F66mHzvD4XQ549606	intact-crc:67554F8FBEB06F98|rigid:iONbbSGxSDbnGs+cYcaSNydYe7s	false	-	sufficient binding region:86-630	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8NHQ1	uniprotkb:P53286	intact:EBI-739624|ensembl:ENSP00000264982|ensembl:ENSP00000419231|uniprotkb:Q96B31|uniprotkb:Q9H2C3|uniprotkb:Q9H2Z1|uniprotkb:Q9H940|uniprotkb:D3DNE9|uniprotkb:B7Z5I8|uniprotkb:B7Z7E8|uniprotkb:F5GZX8	intact:EBI-3796|uniprotkb:D6VUS2|ensemblfungi:YGR142W	psi-mi:cep70_human(display_long)|uniprotkb:CEP70(gene name)|psi-mi:CEP70(display_short)|uniprotkb:BITE(gene name synonym)|uniprotkb:p10-binding protein(gene name synonym)	psi-mi:btn2_yeast(display_long)|uniprotkb:YGR142W(locus name)|uniprotkb:BTN2(gene name)|psi-mi:BTN2(display_short)|uniprotkb:Batten disease protein 2(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11533378|imex:IM-24995-1154	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114107(gene)|ensembl:ENST00000264982(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|interpro:IPR019734|interpro:IPR037692|mint:Q8NHQ1|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|ensembl:ENST00000484888(transcript)|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_077817.2|refseq:XP_016862764.1|refseq:NP_001275893.1|refseq:NP_001275894.1|refseq:NP_001275895.1|refseq:NP_001275896.1|refseq:NP_001307527.1|refseq:NP_001307529.1|entrezgene/locuslink:80321(identity)	sgd:S000003374|refseq:NP_011658.3|dip:DIP-5534N|mint:P53286|ensemblfungi:YGR142W(gene)|ensemblfungi:YGR142W_mRNA(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005634"(nucleus)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006865"(amino acid transport)|go:"GO:0006885"(regulation of pH)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051087"(chaperone binding)|go:"GO:0140311"(protein sequestering activity)|sgd:YGR142W(identity)	-	-	crc64:E7AE1EB1E3612F3E	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:S4yveQWcvdVtAUX65gqrJ5Dv0Mc9606	rogid:Cu27xkwGMNyS4zLvUaG1UeH2mE0559292	intact-crc:2E9FD92139B4A132|rigid:kjA+AlYSmx6ikhMZAUDlty+Ng0g	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P53286	uniprotkb:Q8N6K7-2	intact:EBI-3796|uniprotkb:D6VUS2|ensemblfungi:YGR142W	intact:EBI-11528848|ensembl:ENSP00000324874	psi-mi:btn2_yeast(display_long)|uniprotkb:YGR142W(locus name)|uniprotkb:BTN2(gene name)|psi-mi:BTN2(display_short)|uniprotkb:Batten disease protein 2(gene name synonym)	psi-mi:q8n6k7-2(display_long)|uniprotkb:SAMD3(gene name)|psi-mi:SAMD3(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11533369|imex:IM-24995-1153	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003374|refseq:NP_011658.3|dip:DIP-5534N|mint:P53286|ensemblfungi:YGR142W(gene)|ensemblfungi:YGR142W_mRNA(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005634"(nucleus)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006865"(amino acid transport)|go:"GO:0006885"(regulation of pH)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051087"(chaperone binding)|go:"GO:0140311"(protein sequestering activity)|sgd:YGR142W(identity)	intact:EBI-748741(isoform-parent)|ensembl:ENSG00000164483(gene)|ensembl:ENST00000324172(transcript)|uniprotkb:Q8N6K7-2(isoform-parent)|entrezgene/locuslink:154075(identity)	-	crc64:E7AE1EB1E3612F3E	isoform-comment:No experimental confirmation available.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Cu27xkwGMNyS4zLvUaG1UeH2mE0559292	rogid:2ZsHFOFMqw/yebw24QlvgpYFVso9606	intact-crc:B657905B37C4D315|rigid:MmC7hO4tzKjiNILYyGE8qh1H7wo	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8IYX7	uniprotkb:P53286	intact:EBI-3957636|ensembl:ENSP00000369907|intact:EBI-10174528|uniprotkb:A8K880|uniprotkb:Q5VY58	intact:EBI-3796|uniprotkb:D6VUS2|ensemblfungi:YGR142W	psi-mi:saxo1_human(display_long)|uniprotkb:SAXO1(gene name)|psi-mi:SAXO1(display_short)|uniprotkb:C9orf138(gene name synonym)|uniprotkb:FAM154A(gene name synonym)	psi-mi:btn2_yeast(display_long)|uniprotkb:YGR142W(locus name)|uniprotkb:BTN2(gene name)|psi-mi:BTN2(display_short)|uniprotkb:Batten disease protein 2(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11533360|imex:IM-24995-1152	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000155875(gene)|ensembl:ENST00000380534(transcript)|go:"GO:0005814"(centriole)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0008017"(microtubule binding)|go:"GO:0009631"(cold acclimation)|go:"GO:0030030"(cell projection organization)|go:"GO:0031514"(motile cilium)|go:"GO:0034453"(microtubule anchoring)|go:"GO:0036064"(ciliary basal body)|go:"GO:0036126"(sperm flagellum)|go:"GO:0045724"(positive regulation of cilium assembly)|go:"GO:0050821"(protein stabilization)|go:"GO:0070417"(cellular response to cold)|interpro:IPR033336|refseq:NP_714918.2|refseq:NP_001273978.1|refseq:NP_001273979.1|entrezgene/locuslink:158297(identity)	sgd:S000003374|refseq:NP_011658.3|dip:DIP-5534N|mint:P53286|ensemblfungi:YGR142W(gene)|ensemblfungi:YGR142W_mRNA(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005634"(nucleus)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006865"(amino acid transport)|go:"GO:0006885"(regulation of pH)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051087"(chaperone binding)|go:"GO:0140311"(protein sequestering activity)|sgd:YGR142W(identity)	-	-	crc64:E7AE1EB1E3612F3E	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:34It0miSDTtv5wwJ+ERHXJzWRiQ9606	rogid:Cu27xkwGMNyS4zLvUaG1UeH2mE0559292	intact-crc:9EA893F020D07EB2|rigid:TDKUHObbGC3hTL1Ypp6YkuVWUjU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8IYA8	uniprotkb:P53286	intact:EBI-8638439|intact:EBI-28969497|ensembl:ENSP00000296449|ensembl:ENSP00000391788|ensembl:ENSP00000407837|uniprotkb:C9JJL0|uniprotkb:Q96LP7|intact:MINT-8162095|uniprotkb:Q05DG9	intact:EBI-3796|uniprotkb:D6VUS2|ensemblfungi:YGR142W	psi-mi:iho1_human(display_long)|uniprotkb:IHO1(gene name)|psi-mi:IHO1(display_short)|uniprotkb:CCDC36(gene name synonym)|uniprotkb:Cancer/testis antigen 74(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 36(gene name synonym)	psi-mi:btn2_yeast(display_long)|uniprotkb:YGR142W(locus name)|uniprotkb:BTN2(gene name)|psi-mi:BTN2(display_short)|uniprotkb:Batten disease protein 2(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11533349|imex:IM-24995-1151	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000296449|ensembl:ENST00000366429|ensembl:ENSP00000403700|ensembl:ENSP00000391788|ensembl:ENSP00000407837|ensembl:ENSG00000173421(gene)|ensembl:ENST00000296449(transcript)|ensembl:ENST00000438782(transcript)|ensembl:ENST00000452691(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0006310"(DNA recombination)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0042138"(meiotic DNA double-strand break formation)|go:"GO:0048477"(oogenesis)|go:"GO:0060629"(regulation of homologous chromosome segregation)|interpro:IPR031529|mint:Q8IYA8|refseq:XP_011531974.1|refseq:XP_011531975.1|refseq:NP_001128669.1|refseq:NP_835467.2|refseq:XP_006713187.1|entrezgene/locuslink:339834(identity)	sgd:S000003374|refseq:NP_011658.3|dip:DIP-5534N|mint:P53286|ensemblfungi:YGR142W(gene)|ensemblfungi:YGR142W_mRNA(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005634"(nucleus)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006865"(amino acid transport)|go:"GO:0006885"(regulation of pH)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051087"(chaperone binding)|go:"GO:0140311"(protein sequestering activity)|sgd:YGR142W(identity)	-	comment:mint	crc64:E7AE1EB1E3612F3E	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:+TNQLExkhmC1NWqsE240Cx7zFVU9606	rogid:Cu27xkwGMNyS4zLvUaG1UeH2mE0559292	intact-crc:A81E3B6E3FEBB264|rigid:/wTZoa7rX6rntZfQHb0One7J6Ew	false	sufficient binding region:11-594	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P53296	intact:EBI-11533440	intact:EBI-3165|uniprotkb:E9P955|ensemblfungi:YGR177C|uniprotkb:D6VUW1	-	psi-mi:atf2_yeast(display_long)|uniprotkb:ATF2(gene name)|psi-mi:ATF2(display_short)|uniprotkb:"Acetyl-CoA:pregnenolone acetyltransferase"(gene name synonym)|uniprotkb:G7135(orf name)|uniprotkb:YGR177C(locus name)	psi-mi:wac(display_short)|psi-mi:EBI-11533440(display_long)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11533438|imex:IM-24995-1160	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011693.1|sgd:S000003409|ensemblfungi:YGR177C(gene)|ensemblfungi:YGR177C_mRNA(transcript)|go:"GO:0004026"(alcohol O-acetyltransferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0008080"(N-acetyltransferase activity)|go:"GO:0008202"(steroid metabolic process)|go:"GO:0009636"(response to toxic substance)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0034209"(sterol acetylation)|go:"GO:1901089"(acetate ester metabolic process involved in fermentation)|interpro:IPR010828(Alcohol acetyltransferase)|dip:DIP-5544N|mint:P53296|sgd:YGR177C(identity)	entrezgene/locuslink:51322(identity)	-	-	no-uniprot-update:	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:tFI+2rcFXzDfDteDJv8wwBGUh0c559292	rogid:1lJ64iBkqUGKNB4Lz3jsp7Xu2nE9606	intact-crc:110F2F0F9A978B42|rigid:trBMDDEA9DoT5CNCQ5Q/nxnBYo8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P53286	uniprotkb:Q9UKT9	intact:EBI-3796|uniprotkb:D6VUS2|ensemblfungi:YGR142W	intact:EBI-747204|uniprotkb:Q8WWQ9|uniprotkb:Q8WWR0|uniprotkb:Q8WWR1|uniprotkb:Q8WWR2|uniprotkb:Q8WWR3|uniprotkb:Q8N574|uniprotkb:B4DVV5|uniprotkb:Q69BL6|uniprotkb:Q69BL7|uniprotkb:Q69BL8|uniprotkb:Q69BL9|uniprotkb:Q69BM0|uniprotkb:Q69BM1|uniprotkb:Q69BM2|uniprotkb:Q69BM3|uniprotkb:Q69BM5|ensembl:ENSP00000344544	psi-mi:btn2_yeast(display_long)|uniprotkb:YGR142W(locus name)|uniprotkb:BTN2(gene name)|psi-mi:BTN2(display_short)|uniprotkb:Batten disease protein 2(gene name synonym)	psi-mi:ikzf3_human(display_long)|uniprotkb:ZNFN1A3(gene name synonym)|uniprotkb:Ikaros family zinc finger protein 3(gene name synonym)|uniprotkb:IKZF3(gene name)|psi-mi:IKZF3(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11533429|imex:IM-24995-1159	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003374|refseq:NP_011658.3|dip:DIP-5534N|mint:P53286|ensemblfungi:YGR142W(gene)|ensemblfungi:YGR142W_mRNA(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005634"(nucleus)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006865"(amino acid transport)|go:"GO:0006885"(regulation of pH)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051087"(chaperone binding)|go:"GO:0140311"(protein sequestering activity)|sgd:YGR142W(identity)	refseq:NP_001271443.1|refseq:NP_001271444.1|refseq:NP_036613.2|refseq:NP_899051.1|refseq:NP_899052.1|refseq:NP_899053.1|refseq:NP_899054.1|refseq:NP_899055.1|refseq:NP_001271445.1|refseq:NP_001244337.1|refseq:NP_001244338.1|refseq:NP_001244339.1|refseq:NP_001244340.1|refseq:NP_001244341.1|refseq:NP_001244342.1|refseq:NP_001244343.1|ensembl:ENSG00000161405(gene)|ensembl:ENST00000346872(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007498"(mesoderm development)|go:"GO:0009617"(response to bacterium)|go:"GO:0030888"(regulation of B cell proliferation)|go:"GO:0042113"(B cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045577"(regulation of B cell differentiation)|go:"GO:0045619"(regulation of lymphocyte differentiation)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|go:"GO:0046872"(metal ion binding)|dip:DIP-56975N|entrezgene/locuslink:22806(identity)	-	crc64:E7AE1EB1E3612F3E	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Cu27xkwGMNyS4zLvUaG1UeH2mE0559292	rogid:2Kp6LefSLfK5VIiE6DmQusFIfMY9606	intact-crc:549A2BC8A3A06273|rigid:M2ObKjk04l5z10jOQwXnunL8BtE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9NRA8	uniprotkb:P53286	intact:EBI-301024|uniprotkb:B1AKL2|uniprotkb:Q8NCF2|uniprotkb:Q9H708|uniprotkb:B2RBF1|ensembl:ENSP00000328103|ensembl:ENSP00000380659|intact:EBI-877635|uniprotkb:B1AKL3	intact:EBI-3796|uniprotkb:D6VUS2|ensemblfungi:YGR142W	psi-mi:4et_human(display_long)|uniprotkb:EIF4ENIF1(gene name)|psi-mi:EIF4ENIF1(display_short)|uniprotkb:Eukaryotic translation initiation factor 4E nuclear import factor 1(gene name synonym)	psi-mi:btn2_yeast(display_long)|uniprotkb:YGR142W(locus name)|uniprotkb:BTN2(gene name)|psi-mi:BTN2(display_short)|uniprotkb:Batten disease protein 2(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11533420|imex:IM-24995-1158	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000328103|ensembl:ENST00000344710|ensembl:ENSP00000342927|ensembl:ENSP00000380659|ensembl:ENSG00000184708(gene)|ensembl:ENST00000330125(transcript)|ensembl:ENST00000397525(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0016020"(membrane)|go:"GO:0016605"(PML body)|go:"GO:0016607"(nuclear speck)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019900"(kinase binding)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0033962"(P-body assembly)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0106289"(negative regulation of deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:1905618"(positive regulation of miRNA-mediated gene silencing by inhibition of translation)|interpro:IPR018862|mint:Q9NRA8|rcsb pdb:5ANR|rcsb pdb:6F9W|rcsb pdb:6X2R|refseq:NP_001157973.1|refseq:NP_001157974.1|refseq:NP_062817.2|refseq:XP_011528582.1|refseq:XP_011528583.1|refseq:XP_005261743.1|refseq:XP_005261744.1|refseq:XP_005261745.1|refseq:XP_016884353.1|entrezgene/locuslink:56478(identity)	sgd:S000003374|refseq:NP_011658.3|dip:DIP-5534N|mint:P53286|ensemblfungi:YGR142W(gene)|ensemblfungi:YGR142W_mRNA(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005634"(nucleus)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006865"(amino acid transport)|go:"GO:0006885"(regulation of pH)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051087"(chaperone binding)|go:"GO:0140311"(protein sequestering activity)|sgd:YGR142W(identity)	-	-	crc64:E7AE1EB1E3612F3E	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:4A9mF81S/ePAraruTNYgovUdkT49606	rogid:Cu27xkwGMNyS4zLvUaG1UeH2mE0559292	intact-crc:8135A258559D1BA2|rigid:rK4UkiAgNVvsp9+KRrX3rwJzKz4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P53286	uniprotkb:Q96Q35-2	intact:EBI-3796|uniprotkb:D6VUS2|ensemblfungi:YGR142W	intact:EBI-11533409|ensembl:ENSP00000376086|ensembl:ENSP00000412073	psi-mi:btn2_yeast(display_long)|uniprotkb:YGR142W(locus name)|uniprotkb:BTN2(gene name)|psi-mi:BTN2(display_short)|uniprotkb:Batten disease protein 2(gene name synonym)	psi-mi:q96q35-2(display_long)|uniprotkb:FLACC1(gene name)|psi-mi:FLACC1(display_short)|uniprotkb:ALS2CR12(gene name synonym)|uniprotkb:Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 12 protein(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11533407|imex:IM-24995-1157	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003374|refseq:NP_011658.3|dip:DIP-5534N|mint:P53286|ensemblfungi:YGR142W(gene)|ensemblfungi:YGR142W_mRNA(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005634"(nucleus)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006865"(amino acid transport)|go:"GO:0006885"(regulation of pH)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051087"(chaperone binding)|go:"GO:0140311"(protein sequestering activity)|sgd:YGR142W(identity)	intact:EBI-750451(isoform-parent)|uniprotkb:Q96Q35-2(isoform-parent)|ensembl:ENSG00000155749(gene)|ensembl:ENST00000392257(transcript)|ensembl:ENST00000439709(transcript)|entrezgene/locuslink:130540(identity)	-	crc64:E7AE1EB1E3612F3E	isoform-comment:No experimental confirmation available.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Cu27xkwGMNyS4zLvUaG1UeH2mE0559292	rogid:bdqsMHSGebh2qVAwEO8DhTbZOHM9606	intact-crc:AE4D3FA4A7A170E3|rigid:fCuK39rzQsrSPULT0uqqR2hP8KQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8WXE1-3	uniprotkb:P53286	intact:EBI-11524582|ensembl:ENSP00000400930	intact:EBI-3796|uniprotkb:D6VUS2|ensemblfungi:YGR142W	psi-mi:q8wxe1-3(display_long)|uniprotkb:ATRIP(gene name)|psi-mi:ATRIP(display_short)|uniprotkb:AGS1(gene name synonym)|uniprotkb:ATM and Rad3-related-interacting protein(gene name synonym)	psi-mi:btn2_yeast(display_long)|uniprotkb:YGR142W(locus name)|uniprotkb:BTN2(gene name)|psi-mi:BTN2(display_short)|uniprotkb:Batten disease protein 2(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11533398|imex:IM-24995-1156	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-747353(isoform-parent)|ensembl:ENSG00000164053(gene)|ensembl:ENST00000412052(transcript)|entrezgene/locuslink:84126(identity)	sgd:S000003374|refseq:NP_011658.3|dip:DIP-5534N|mint:P53286|ensemblfungi:YGR142W(gene)|ensemblfungi:YGR142W_mRNA(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005634"(nucleus)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006865"(amino acid transport)|go:"GO:0006885"(regulation of pH)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051087"(chaperone binding)|go:"GO:0140311"(protein sequestering activity)|sgd:YGR142W(identity)	-	isoform-comment:No experimental confirmation available.	crc64:E7AE1EB1E3612F3E	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:NKCjy1jGZEySEhUOf8rJ6h9pyxY9606	rogid:Cu27xkwGMNyS4zLvUaG1UeH2mE0559292	intact-crc:797686E20AE38608|rigid:QecK8SllrIfV258shEgboJCRAHg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P53305	uniprotkb:O14641	intact:EBI-23490|uniprotkb:D6VUZ8|ensemblfungi:YGR215W	intact:EBI-740850|ensembl:ENSP00000005340|uniprotkb:Q53XM0|uniprotkb:D3DTN3	psi-mi:rt27_yeast(display_long)|uniprotkb:RSM27(gene name)|psi-mi:RSM27(display_short)|uniprotkb:Mitochondrial small ribosomal subunit protein mS33(gene name synonym)|uniprotkb:YGR215W(locus name)	psi-mi:dvl2_human(display_long)|uniprotkb:DSH homolog 2(gene name synonym)|uniprotkb:DVL2(gene name)|psi-mi:DVL2(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11533486|imex:IM-24995-1165	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003447|refseq:NP_011731.3|dip:DIP-5606N|mint:P53305|ensemblfungi:YGR215W(gene)|ensemblfungi:YGR215W_mRNA(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR013219(Ribosomal protein S27, mitochondrial)|rcsb pdb:5MRC|rcsb pdb:5MRE|rcsb pdb:5MRF|sgd:YGR215W(identity)	refseq:NP_004413.1|ensembl:ENSG00000004975(gene)|ensembl:ENST00000005340(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005109"(frizzled binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0007507"(heart development)|go:"GO:0016235"(aggresome)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044340"(canonical Wnt signaling pathway involved in regulation of cell proliferation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0150012"(positive regulation of neuron projection arborization)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008341(Dishevelled-2 region)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:O14641|rcsb pdb:2REY|rcsb pdb:3CBX|rcsb pdb:3CBY|rcsb pdb:3CBZ|rcsb pdb:3CC0|rcsb pdb:4WIP|rcsb pdb:5LNP|rcsb pdb:5SUY|rcsb pdb:5SUZ|rcsb pdb:6IW3|rcsb pdb:6JCK|reactome:R-HSA-201681|reactome:R-HSA-201688|reactome:R-HSA-2028269|reactome:R-HSA-4086400|reactome:R-HSA-4608870|reactome:R-HSA-4641258|reactome:R-HSA-4641262|reactome:R-HSA-5099900|reactome:R-HSA-5368598|reactome:R-HSA-5663220|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9673324|ensembl:ENSP00000005340|dip:DIP-34433N|entrezgene/locuslink:1856(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:IRBztDEm6s+cFbpp3GkrlJgUdp4559292	rogid:2Vdc8oRnT4Mz/j+EXQXrL3AszOc9606	intact-crc:0DB938463E75DAA4|rigid:1lEmCr91dLNwbHoUQylCqMMvyNk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P53296	uniprotkb:Q9UI14	intact:EBI-3165|uniprotkb:E9P955|ensemblfungi:YGR177C|uniprotkb:D6VUW1	intact:EBI-712367|ensembl:ENSP00000222008|uniprotkb:Q7Z4Y2|uniprotkb:Q9Y3R1	psi-mi:atf2_yeast(display_long)|uniprotkb:ATF2(gene name)|psi-mi:ATF2(display_short)|uniprotkb:"Acetyl-CoA:pregnenolone acetyltransferase"(gene name synonym)|uniprotkb:G7135(orf name)|uniprotkb:YGR177C(locus name)	psi-mi:praf1_human(display_long)|uniprotkb:PRA1 family protein 1(gene name synonym)|uniprotkb:RABAC1(gene name)|psi-mi:RABAC1(display_short)|uniprotkb:PRA1(gene name synonym)|uniprotkb:PRAF1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11533477|imex:IM-24995-1164	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011693.1|sgd:S000003409|ensemblfungi:YGR177C(gene)|ensemblfungi:YGR177C_mRNA(transcript)|go:"GO:0004026"(alcohol O-acetyltransferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0008080"(N-acetyltransferase activity)|go:"GO:0008202"(steroid metabolic process)|go:"GO:0009636"(response to toxic substance)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0034209"(sterol acetylation)|go:"GO:1901089"(acetate ester metabolic process involved in fermentation)|interpro:IPR010828(Alcohol acetyltransferase)|dip:DIP-5544N|mint:P53296|sgd:YGR177C(identity)	refseq:NP_006414.2|ensembl:ENSG00000105404(gene)|ensembl:ENST00000222008(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0070064"(proline-rich region binding)|interpro:IPR004895(Prenylated rab acceptor PRA1)|mint:Q9UI14|entrezgene/locuslink:10567(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:tFI+2rcFXzDfDteDJv8wwBGUh0c559292	rogid:WS2rUY7yXRbR7pqWgfUCbnEiDbg9606	intact-crc:D99FCCEC1A2D8E4E|rigid:mh1TetBF8MwxyPIhB9F7I1csQsE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P53296	uniprotkb:Q9NQC3-3	intact:EBI-3165|uniprotkb:E9P955|ensemblfungi:YGR177C|uniprotkb:D6VUW1	intact:EBI-11526335|ensembl:ENSP00000378107	psi-mi:atf2_yeast(display_long)|uniprotkb:ATF2(gene name)|psi-mi:ATF2(display_short)|uniprotkb:"Acetyl-CoA:pregnenolone acetyltransferase"(gene name synonym)|uniprotkb:G7135(orf name)|uniprotkb:YGR177C(locus name)	psi-mi:q9nqc3-3(display_long)|uniprotkb:Foocen(gene name synonym)|uniprotkb:KIAA0886(gene name synonym)|uniprotkb:NOGO(gene name synonym)|uniprotkb:Neurite outgrowth inhibitor(gene name synonym)|uniprotkb:Neuroendocrine-specific protein(gene name synonym)|uniprotkb:Neuroendocrine-specific protein C homolog(gene name synonym)|uniprotkb:RTN-x(gene name synonym)|uniprotkb:Reticulon-5(gene name synonym)|uniprotkb:My043(orf name)|uniprotkb:SP1507(orf name)|uniprotkb:Foocen-S(isoform synonym)|uniprotkb:Nogo-C(isoform synonym)|uniprotkb:RTN4(gene name)|psi-mi:RTN4(display_short)|uniprotkb:RTN4C(isoform synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11533468|imex:IM-24995-1163	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011693.1|sgd:S000003409|ensemblfungi:YGR177C(gene)|ensemblfungi:YGR177C_mRNA(transcript)|go:"GO:0004026"(alcohol O-acetyltransferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0008080"(N-acetyltransferase activity)|go:"GO:0008202"(steroid metabolic process)|go:"GO:0009636"(response to toxic substance)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0034209"(sterol acetylation)|go:"GO:1901089"(acetate ester metabolic process involved in fermentation)|interpro:IPR010828(Alcohol acetyltransferase)|dip:DIP-5544N|mint:P53296|sgd:YGR177C(identity)	intact:EBI-715945(isoform-parent)|ensembl:ENSG00000115310(gene)|ensembl:ENST00000394609(transcript)|entrezgene/locuslink:57142(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:tFI+2rcFXzDfDteDJv8wwBGUh0c559292	rogid:Iq/LlFtXjFyIIfxZ1l3NTKURpyA9606	intact-crc:8925E0960C0D0268|rigid:YGDqpIyHMtZotWwLPGQNqshzKi0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P53296	uniprotkb:Q15041	intact:EBI-3165|uniprotkb:E9P955|ensemblfungi:YGR177C|uniprotkb:D6VUW1	intact:EBI-714543|ensembl:ENSP00000306788|uniprotkb:B7Z6S5|uniprotkb:B7Z791|uniprotkb:F5GXP4	psi-mi:atf2_yeast(display_long)|uniprotkb:ATF2(gene name)|psi-mi:ATF2(display_short)|uniprotkb:"Acetyl-CoA:pregnenolone acetyltransferase"(gene name synonym)|uniprotkb:G7135(orf name)|uniprotkb:YGR177C(locus name)	psi-mi:ar6p1_human(display_long)|uniprotkb:ARL6IP(gene name synonym)|uniprotkb:ARL6IP1(gene name)|psi-mi:ARL6IP1(display_short)|uniprotkb:KIAA0069(gene name synonym)|uniprotkb:ARMER(gene name synonym)|uniprotkb:Apoptotic regulator in the membrane of the endoplasmic reticulum(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11533459|imex:IM-24995-1162	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011693.1|sgd:S000003409|ensemblfungi:YGR177C(gene)|ensemblfungi:YGR177C_mRNA(transcript)|go:"GO:0004026"(alcohol O-acetyltransferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0008080"(N-acetyltransferase activity)|go:"GO:0008202"(steroid metabolic process)|go:"GO:0009636"(response to toxic substance)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0034209"(sterol acetylation)|go:"GO:1901089"(acetate ester metabolic process involved in fermentation)|interpro:IPR010828(Alcohol acetyltransferase)|dip:DIP-5544N|mint:P53296|sgd:YGR177C(identity)	refseq:NP_055976.1|ensembl:ENSG00000170540(gene)|ensembl:ENST00000304414(transcript)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006613"(cotranslational protein targeting to membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0071787"(endoplasmic reticulum tubular network formation)|go:"GO:1903371"(regulation of endoplasmic reticulum tubular network organization)|go:"GO:1990809"(endoplasmic reticulum tubular network membrane organization)|interpro:IPR033301|mint:Q15041|go:"GO:0002038"(positive regulation of L-glutamate import across plasma membrane)|refseq:NP_001300787.1|entrezgene/locuslink:23204(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:tFI+2rcFXzDfDteDJv8wwBGUh0c559292	rogid:3fjkoyvUx25po7xsPcXgpjEeLJg9606	intact-crc:3CAB65ED95E186C7|rigid:xG/zV4XbXvlA5eYSWH2Ko7n+JJ0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49366	uniprotkb:P53331	intact:EBI-741925|ensembl:ENSP00000210060|uniprotkb:Q13184|uniprotkb:Q13276|uniprotkb:A8K688|uniprotkb:Q9UDG0|uniprotkb:M0R1I5	intact:EBI-23641|uniprotkb:D6VV53|ensemblfungi:YGR276C	psi-mi:dhys_human(display_long)|uniprotkb:DHPS(gene name)|psi-mi:DHPS(display_short)|uniprotkb:DS(gene name synonym)	psi-mi:rexo1_yeast(display_long)|uniprotkb:YGR276C(locus name)|uniprotkb:G9381(orf name)|uniprotkb:RNH70(gene name)|psi-mi:RNH70(display_short)|uniprotkb:REX1(gene name synonym)|uniprotkb:"RNase H(70)"(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11533495|imex:IM-24995-1166	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001193903.1|ensembl:ENSG00000095059(gene)|ensembl:ENST00000210060(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0008216"(spermidine metabolic process)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008612"(peptidyl-lysine modification to peptidyl-hypusine)|go:"GO:0034038"(deoxyhypusine synthase activity)|go:"GO:0042802"(identical protein binding)|interpro:IPR002773(Deoxyhypusine synthase)|interpro:IPR029035|interpro:IPR036982|mint:P49366|rcsb pdb:1DHS|rcsb pdb:1RLZ|rcsb pdb:1ROZ|rcsb pdb:1RQD|refseq:NP_001921.1|refseq:NP_037538.1|rcsb pdb:6P4V|rcsb pdb:6PGR|rcsb pdb:6WKZ|rcsb pdb:6WL6|rcsb pdb:6XXH|rcsb pdb:6XXI|rcsb pdb:6XXJ|rcsb pdb:6XXK|rcsb pdb:6XXL|rcsb pdb:6XXM|reactome:R-HSA-204626|refseq:XP_011526072.1|entrezgene/locuslink:1725(identity)	refseq:NP_011792.1|sgd:S000003508|dip:DIP-5564N|ensemblfungi:YGR276C(gene)|ensemblfungi:YGR276C_mRNA(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0002107"(generation of mature 3'-end of 5S rRNA generated by RNA polymerase III)|go:"GO:0003723"(RNA binding)|go:"GO:0004527"(exonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0008408"(3'-5' exonuclease activity)|go:"GO:0034415"(tRNA 3'-trailer cleavage, exonucleolytic)|go:"GO:0034476"(U5 snRNA 3'-end processing)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR013520(Exonuclease, RNase T and DNA polymerase III)|interpro:IPR034922|interpro:IPR036397|sgd:YGR276C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:4MuV3m6JWYn3kCENrfcLU6GAkto9606	rogid:mkFn9c/1OdcUX9TOL2m2kGd0K90559292	intact-crc:DD4F01973ED96643|rigid:2iJTqgivkLzk6BO5esa3v2uJU0s	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P53296	uniprotkb:O95197-3	intact:EBI-3165|uniprotkb:E9P955|ensemblfungi:YGR177C|uniprotkb:D6VUW1	intact:EBI-11525735|ensembl:ENSP00000440874	psi-mi:atf2_yeast(display_long)|uniprotkb:ATF2(gene name)|psi-mi:ATF2(display_short)|uniprotkb:"Acetyl-CoA:pregnenolone acetyltransferase"(gene name synonym)|uniprotkb:G7135(orf name)|uniprotkb:YGR177C(locus name)	psi-mi:o95197-3(display_long)|uniprotkb:RTN3(gene name)|psi-mi:RTN3(display_short)|uniprotkb:ASYIP(gene name synonym)|uniprotkb:Homolog of ASY protein(gene name synonym)|uniprotkb:NSPL2(gene name synonym)|uniprotkb:Neuroendocrine-specific protein-like 2(gene name synonym)|uniprotkb:Neuroendocrine-specific protein-like II(gene name synonym)|uniprotkb:A1(isoform synonym)|uniprotkb:B1(isoform synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11533450|imex:IM-24995-1161	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011693.1|sgd:S000003409|ensemblfungi:YGR177C(gene)|ensemblfungi:YGR177C_mRNA(transcript)|go:"GO:0004026"(alcohol O-acetyltransferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0008080"(N-acetyltransferase activity)|go:"GO:0008202"(steroid metabolic process)|go:"GO:0009636"(response to toxic substance)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0034209"(sterol acetylation)|go:"GO:1901089"(acetate ester metabolic process involved in fermentation)|interpro:IPR010828(Alcohol acetyltransferase)|dip:DIP-5544N|mint:P53296|sgd:YGR177C(identity)	ensembl:ENSG00000133318(gene)|ensembl:ENST00000537981(transcript)|intact:EBI-740467(isoform-parent)|uniprotkb:O95197-3(isoform-parent)|entrezgene/locuslink:10313(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:tFI+2rcFXzDfDteDJv8wwBGUh0c559292	rogid:+TJnANu85CM52dRZ6s+hYMlUABE9606	intact-crc:20FAC4AD066873BD|rigid:DyoaHsZ294v67cad9fx6YHSXQkY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P53583	uniprotkb:P50222	intact:EBI-11174|uniprotkb:D6W0U4|ensemblfungi:YNL249C	intact:EBI-748397|uniprotkb:O75263|ensembl:ENSP00000262041|uniprotkb:Q9UPL6|uniprotkb:B2R8I7|intact:EBI-10172134|intact:EBI-11522964|intact:EBI-11750003|intact:EBI-12702266|uniprotkb:A4D127	psi-mi:mpa43_yeast(display_long)|uniprotkb:N0875(orf name)|uniprotkb:YNL249C(locus name)|uniprotkb:MPA43(gene name)|psi-mi:MPA43(display_short)	psi-mi:meox2_human(display_long)|uniprotkb:Mesenchyme homeobox 2(gene name synonym)|uniprotkb:Growth arrest-specific homeobox(gene name synonym)|uniprotkb:MEOX2(gene name)|psi-mi:MEOX2(display_short)|uniprotkb:GAX(gene name synonym)|uniprotkb:MOX2(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11533541|imex:IM-24995-1171	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YNL249C(gene)|ensemblfungi:YNL249C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0016773"(phosphotransferase activity, alcohol group as acceptor)|refseq:NP_014150.1|sgd:S000005193|interpro:IPR018485|interpro:IPR018484|interpro:IPR043129|sgd:YNL249C(identity)	ensembl:ENSG00000106511(gene)|ensembl:ENST00000262041(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0001757"(somite specification)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007275"(multicellular organism development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008015"(blood circulation)|go:"GO:0016607"(nuclear speck)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060173"(limb development)|go:"GO:0061053"(somite development)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR042634|refseq:NP_005915.2|entrezgene/locuslink:4223(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2017/05/26	rogid:QQDVGr5IRob5uHE4ZvFNeyAgkZo559292	rogid:fMv0ruKikzQ3MC0PBvJ3pOAjW+U9606	intact-crc:6E526F94BCEF649E|rigid:08riUNnYPva+PY8cYs0aWMzSTiE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P53337	uniprotkb:Q8N6L0	intact:EBI-23662|uniprotkb:E9P8T4|uniprotkb:D6VV61|ensemblfungi:YGR284C	intact:EBI-749265|uniprotkb:Q96MC3|ensembl:ENSP00000404220	psi-mi:erv29_yeast(display_long)|uniprotkb:ERV29(gene name)|psi-mi:ERV29(display_short)|uniprotkb:YGR284C(locus name)	psi-mi:kash5_human(display_long)|uniprotkb:KASH5(gene name)|psi-mi:KASH5(display_short)|uniprotkb:CCDC155(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 155(gene name synonym)|uniprotkb:KASH domain-containing protein 5(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11533532|imex:IM-24995-1170	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011800.3|sgd:S000003516|dip:DIP-8110N|mint:P53337|ensemblfungi:YGR284C(gene)|ensemblfungi:YGR284C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0097020"(COPII receptor activity)|interpro:IPR002995(Surfeit locus 4)|reactome:R-SCE-6798695|reactome:R-SCE-6811434|sgd:YGR284C(identity)	refseq:NP_653289.3|ensembl:ENSG00000161609(gene)|ensembl:ENST00000447857(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034397"(telomere localization)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051225"(spindle assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0090172"(microtubule cytoskeleton organization involved in homologous chromosome segregation)|go:"GO:0090220"(chromosome localization to nuclear envelope involved in homologous chromosome segregation)|go:"GO:0090619"(meiotic spindle pole)|interpro:IPR011992(EF-Hand type)|interpro:IPR028168|interpro:IPR028170|interpro:IPR039508|mint:Q8N6L0|rcsb pdb:6R2I|rcsb pdb:6WMF|entrezgene/locuslink:147872(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:vlRDf0B9mDUXU6M2tLAiWqX4wN8559292	rogid:Wl9L7AcvDHCZuKjYLn8QgGIbZTc9606	intact-crc:B8991D5364999263|rigid:tBRhPS3XijxnDuDFWhH4kh8Nlf0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O14641	uniprotkb:P53617	intact:EBI-740850|ensembl:ENSP00000005340|uniprotkb:Q53XM0|uniprotkb:D3DTN3	intact:EBI-12228|ensemblfungi:YNL251C|uniprotkb:D6W0U2	psi-mi:dvl2_human(display_long)|uniprotkb:DSH homolog 2(gene name synonym)|uniprotkb:DVL2(gene name)|psi-mi:DVL2(display_short)	psi-mi:nrd1_yeast(display_long)|uniprotkb:N0868(orf name)|uniprotkb:YNL251C(locus name)|uniprotkb:NRD1(gene name)|psi-mi:NRD1(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11533550|imex:IM-24995-1172	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004413.1|ensembl:ENSG00000004975(gene)|ensembl:ENST00000005340(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005109"(frizzled binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0007507"(heart development)|go:"GO:0016235"(aggresome)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044340"(canonical Wnt signaling pathway involved in regulation of cell proliferation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0150012"(positive regulation of neuron projection arborization)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008341(Dishevelled-2 region)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:O14641|rcsb pdb:2REY|rcsb pdb:3CBX|rcsb pdb:3CBY|rcsb pdb:3CBZ|rcsb pdb:3CC0|rcsb pdb:4WIP|rcsb pdb:5LNP|rcsb pdb:5SUY|rcsb pdb:5SUZ|rcsb pdb:6IW3|rcsb pdb:6JCK|reactome:R-HSA-201681|reactome:R-HSA-201688|reactome:R-HSA-2028269|reactome:R-HSA-4086400|reactome:R-HSA-4608870|reactome:R-HSA-4641258|reactome:R-HSA-4641262|reactome:R-HSA-5099900|reactome:R-HSA-5368598|reactome:R-HSA-5663220|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9673324|ensembl:ENSP00000005340|dip:DIP-34433N|entrezgene/locuslink:1856(identity)	ensemblfungi:YNL251C(gene)|ensemblfungi:YNL251C_mRNA(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001068"(transcription regulatory region RNA binding)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030847"(termination of RNA polymerase II transcription, exosome-dependent)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0031126"("sno(s)RNA 3'-end processing")|go:"GO:0034472"(snRNA 3'-end processing)|go:"GO:0035649"(Nrd1 complex)|go:"GO:0042780"(tRNA 3'-end processing)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071034"(CUT catabolic process)|go:"GO:0071041"(antisense RNA transcript catabolic process)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR006569(Regulation of nuclear pre-mRNA protein)|interpro:IPR008942(ENTH/VHS)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034894|interpro:IPR035979|rcsb pdb:2LO6|rcsb pdb:2M88|rcsb pdb:2MOW|rcsb pdb:3CLJ|rcsb pdb:5O1T|rcsb pdb:5O1W|rcsb pdb:5O1X|rcsb pdb:5O1Y|rcsb pdb:5O1Z|rcsb pdb:5O20|rcsb pdb:6GC3|rcsb pdb:6O3W|rcsb pdb:6O3X|rcsb pdb:6O3Y|refseq:NP_014148.1|sgd:S000005195|mint:P53617|dip:DIP-6778N|sgd:YNL251C(identity)	-	-	crc64:75082BDB0C42AE37	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:2Vdc8oRnT4Mz/j+EXQXrL3AszOc9606	rogid:FJJxQtZfVVwYERLXtGkq6cJ9I1U559292	intact-crc:3AA22F8960CBD675|rigid:v77/dYwCC7t3dG3yE5DadupUjf0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P53335	uniprotkb:Q8NHQ1	intact:EBI-23652|uniprotkb:D6VV57|uniprotkb:Q8TG89|intact:EBI-33325|ensemblfungi:YGR280C	intact:EBI-739624|ensembl:ENSP00000264982|ensembl:ENSP00000419231|uniprotkb:Q96B31|uniprotkb:Q9H2C3|uniprotkb:Q9H2Z1|uniprotkb:Q9H940|uniprotkb:D3DNE9|uniprotkb:B7Z5I8|uniprotkb:B7Z7E8|uniprotkb:F5GZX8	psi-mi:pxr1_yeast(display_long)|uniprotkb:PXR1(gene name)|psi-mi:PXR1(display_short)|uniprotkb:GNO1(gene name synonym)|uniprotkb:PinX1-related protein 1(gene name synonym)|uniprotkb:G-patch nucleolar protein(gene name synonym)|uniprotkb:YGR280C(locus name)	psi-mi:cep70_human(display_long)|uniprotkb:CEP70(gene name)|psi-mi:CEP70(display_short)|uniprotkb:BITE(gene name synonym)|uniprotkb:p10-binding protein(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11533504|imex:IM-24995-1167	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011796.1|sgd:S000003512|dip:DIP-4308N|mint:P53335|ensemblfungi:YGR280C(gene)|ensemblfungi:YGR280C_mRNA(transcript)|go:"GO:0000494"(box C/D RNA 3'-end processing)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0010521"(telomerase inhibitor activity)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|interpro:IPR000467(D111/G-patch)|sgd:YGR280C(identity)	ensembl:ENSG00000114107(gene)|ensembl:ENST00000264982(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|interpro:IPR019734|interpro:IPR037692|mint:Q8NHQ1|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|ensembl:ENST00000484888(transcript)|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_077817.2|refseq:XP_016862764.1|refseq:NP_001275893.1|refseq:NP_001275894.1|refseq:NP_001275895.1|refseq:NP_001275896.1|refseq:NP_001307527.1|refseq:NP_001307529.1|entrezgene/locuslink:80321(identity)	-	crc64:D5AB6EB2C129922D	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:SzQtp13uvK3KbuNHyZQPJxKMzwY559292	rogid:S4yveQWcvdVtAUX65gqrJ5Dv0Mc9606	intact-crc:56D35EFBC9C899E7|rigid:w7ywsBjZq3ZfPloH3tu3ec70B7c	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9NVV9	uniprotkb:P53335	intact:EBI-741515|uniprotkb:Q53FQ1|uniprotkb:Q6IA99|ensembl:ENSP00000254250|uniprotkb:A6NCB6|uniprotkb:D3DSY5|uniprotkb:H9KV49	intact:EBI-23652|uniprotkb:D6VV57|uniprotkb:Q8TG89|intact:EBI-33325|ensemblfungi:YGR280C	psi-mi:thap1_human(display_long)|uniprotkb:THAP1(gene name)|psi-mi:THAP1(display_short)	psi-mi:pxr1_yeast(display_long)|uniprotkb:PXR1(gene name)|psi-mi:PXR1(display_short)|uniprotkb:GNO1(gene name synonym)|uniprotkb:PinX1-related protein 1(gene name synonym)|uniprotkb:G-patch nucleolar protein(gene name synonym)|uniprotkb:YGR280C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11533513|imex:IM-24995-1168	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060575.1|ensembl:ENSG00000131931(gene)|ensembl:ENST00000254250(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001650"(fibrillar center)|go:"GO:0001935"(endothelial cell proliferation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007049"(cell cycle)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016605"(PML body)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR006612(Zinc finger, C2CH-type)|interpro:IPR026516|interpro:IPR038441|mint:Q9NVV9|rcsb pdb:2JTG|rcsb pdb:2KO0|rcsb pdb:2L1G|refseq:NP_945354.1|entrezgene/locuslink:55145(identity)	refseq:NP_011796.1|sgd:S000003512|dip:DIP-4308N|mint:P53335|ensemblfungi:YGR280C(gene)|ensemblfungi:YGR280C_mRNA(transcript)|go:"GO:0000494"(box C/D RNA 3'-end processing)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0010521"(telomerase inhibitor activity)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|interpro:IPR000467(D111/G-patch)|sgd:YGR280C(identity)	-	-	crc64:D5AB6EB2C129922D	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:/KO90pu5tBnIVq9SMx1JYPXFCEQ9606	rogid:SzQtp13uvK3KbuNHyZQPJxKMzwY559292	intact-crc:D368DABCF5A029F4|rigid:3ht2BQNn8IjNP9ovA40HOmWiBTc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P53337	uniprotkb:Q15437	intact:EBI-23662|uniprotkb:E9P8T4|uniprotkb:D6VV61|ensemblfungi:YGR284C	intact:EBI-742673|uniprotkb:Q5W183|uniprotkb:Q9BS15|uniprotkb:Q9BSI2|uniprotkb:Q9H1D7|intact:EBI-1048165|uniprotkb:Q503A9|uniprotkb:D3DW33|ensembl:ENSP00000262544|ensembl:ENSP00000338844|ensembl:ENSP00000366685|ensembl:ENSP00000497473	psi-mi:erv29_yeast(display_long)|uniprotkb:ERV29(gene name)|psi-mi:ERV29(display_short)|uniprotkb:YGR284C(locus name)	psi-mi:sc23b_human(display_long)|uniprotkb:SEC23-related protein B(gene name synonym)|uniprotkb:SEC23B(gene name)|psi-mi:SEC23B(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11533522|imex:IM-24995-1169	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011800.3|sgd:S000003516|dip:DIP-8110N|mint:P53337|ensemblfungi:YGR284C(gene)|ensemblfungi:YGR284C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0097020"(COPII receptor activity)|interpro:IPR002995(Surfeit locus 4)|reactome:R-SCE-6798695|reactome:R-SCE-6811434|sgd:YGR284C(identity)	refseq:NP_001166216.1|refseq:NP_006354.2|refseq:NP_116780.1|refseq:NP_116781.1|ensembl:ENSG00000101310(gene)|ensembl:ENST00000262544(transcript)|ensembl:ENST00000336714(transcript)|ensembl:ENST00000377465(transcript)|ensembl:ENST00000650089(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008270"(zinc ion binding)|go:"GO:0012505"(endomembrane system)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0090110"(COPII-coated vesicle cargo loading)|go:"GO:0070971"(endoplasmic reticulum exit site)|interpro:IPR006895(Zinc finger, Sec23/Sec24-type)|interpro:IPR006896(Sec23/Sec24 trunk region)|interpro:IPR006900(Sec23/Sec24 helical region)|interpro:IPR007123(Gelsolin region)|interpro:IPR012990(Sec23/Sec24 beta-sandwich)|interpro:IPR029006|interpro:IPR036174|interpro:IPR036175|interpro:IPR036180|interpro:IPR036465|interpro:IPR037364|interpro:IPR037550|mint:Q15437|refseq:XP_016883082.1|entrezgene/locuslink:10483(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:vlRDf0B9mDUXU6M2tLAiWqX4wN8559292	rogid:+3KZ/1jjziSgJRcr81Axquofkl49606	intact-crc:172A57687FB8000A|rigid:6ziWyI9R7/6JLtW/u8QQLPdTMm4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P53829	uniprotkb:Q08379	intact:EBI-28306|uniprotkb:D6W0Q5|ensemblfungi:YNL288W	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	psi-mi:caf40_yeast(display_long)|uniprotkb:YNL288W(locus name)|uniprotkb:N0540(orf name)|uniprotkb:40 kDa CCR4-associated factor(gene name synonym)|uniprotkb:CAF40(gene name)|psi-mi:CAF40(display_short)	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11533577|imex:IM-24995-1175	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014111.1|sgd:S000005232|dip:DIP-1995N|mint:P53829|ensemblfungi:YNL288W(gene)|ensemblfungi:YNL288W_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR007216(Cell differentiation, Rcd1-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:4CV5|sgd:YNL288W(identity)	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N|entrezgene/locuslink:2801(identity)	-	crc64:F3DBABE6AD3C7F3C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2017/05/26	rogid:etuSSgFGQOcgxPDexEXUqQg6H5s559292	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	intact-crc:BB75B4E7B18E8E01|rigid:AIaiRZZYO7SNUfkmNR2PvjYLdGs	false	-	sufficient binding region:383-1002	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8N6L0	uniprotkb:P53730	intact:EBI-749265|uniprotkb:Q96MC3|ensembl:ENSP00000404220	intact:EBI-28496|uniprotkb:D6W1K4|ensemblfungi:YNR030W	psi-mi:kash5_human(display_long)|uniprotkb:KASH5(gene name)|psi-mi:KASH5(display_short)|uniprotkb:CCDC155(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 155(gene name synonym)|uniprotkb:KASH domain-containing protein 5(gene name synonym)	psi-mi:alg12_yeast(display_long)|uniprotkb:ALG12(gene name)|psi-mi:ALG12(display_short)|uniprotkb:ECM39(gene name synonym)|uniprotkb:YNR030W(locus name)|uniprotkb:N3265(orf name)|uniprotkb:Mannosyltransferase ALG12(gene name synonym)|uniprotkb:Extracellular mutant protein 39(gene name synonym)|uniprotkb:"Dolichyl-P-Man:Man(7)GlcNAc(2)-PP-dolichyl-alpha-1,6-mannosyltransferase"(gene name synonym)|uniprotkb:Asparagine-linked glycosylation protein 12(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11533568|imex:IM-24995-1174	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_653289.3|ensembl:ENSG00000161609(gene)|ensembl:ENST00000447857(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034397"(telomere localization)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051225"(spindle assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0090172"(microtubule cytoskeleton organization involved in homologous chromosome segregation)|go:"GO:0090220"(chromosome localization to nuclear envelope involved in homologous chromosome segregation)|go:"GO:0090619"(meiotic spindle pole)|interpro:IPR011992(EF-Hand type)|interpro:IPR028168|interpro:IPR028170|interpro:IPR039508|mint:Q8N6L0|rcsb pdb:6R2I|rcsb pdb:6WMF|entrezgene/locuslink:147872(identity)	refseq:NP_014427.1|sgd:S000005313|dip:DIP-4259N|mint:P53730|ensemblfungi:YNR030W(gene)|ensemblfungi:YNR030W_mRNA(transcript)|go:"GO:0000009"(alpha-1,6-mannosyltransferase activity)|go:"GO:0000030"(mannosyltransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0006488"(dolichol-linked oligosaccharide biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0052917"("dolichyl-P-Man:Man(7)GlcNAc(2)-PP-dolichol alpha-1,6-mannosyltransferase")|interpro:IPR005599(Alg9-like mannosyltransferase)|interpro:IPR039485|reactome:R-SCE-446193|sgd:YNR030W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Wl9L7AcvDHCZuKjYLn8QgGIbZTc9606	rogid:3OdDOcUZm9NImnU+imd8xJwvb/Q559292	intact-crc:9B53C741AB6503AC|rigid:zUZNmmlYHAgkp51A+owZX2vazzw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O95751	uniprotkb:P53617	intact:EBI-740738|ensembl:ENSP00000359557|uniprotkb:Q6IAR6	intact:EBI-12228|ensemblfungi:YNL251C|uniprotkb:D6W0U2	psi-mi:ldoc1_human(display_long)|uniprotkb:Leucine zipper protein down-regulated in cancer cells(gene name synonym)|uniprotkb:LDOC1(gene name)|psi-mi:LDOC1(display_short)|uniprotkb:BCUR1(gene name synonym)	psi-mi:nrd1_yeast(display_long)|uniprotkb:N0868(orf name)|uniprotkb:YNL251C(locus name)|uniprotkb:NRD1(gene name)|psi-mi:NRD1(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11533559|imex:IM-24995-1173	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_036449.1|ensembl:ENSG00000182195(gene)|ensembl:ENST00000370526(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071225"(cellular response to muramyl dipeptide)|interpro:IPR032549|interpro:IPR032567|entrezgene/locuslink:23641(identity)	ensemblfungi:YNL251C(gene)|ensemblfungi:YNL251C_mRNA(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001068"(transcription regulatory region RNA binding)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030847"(termination of RNA polymerase II transcription, exosome-dependent)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0031126"("sno(s)RNA 3'-end processing")|go:"GO:0034472"(snRNA 3'-end processing)|go:"GO:0035649"(Nrd1 complex)|go:"GO:0042780"(tRNA 3'-end processing)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071034"(CUT catabolic process)|go:"GO:0071041"(antisense RNA transcript catabolic process)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR006569(Regulation of nuclear pre-mRNA protein)|interpro:IPR008942(ENTH/VHS)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034894|interpro:IPR035979|rcsb pdb:2LO6|rcsb pdb:2M88|rcsb pdb:2MOW|rcsb pdb:3CLJ|rcsb pdb:5O1T|rcsb pdb:5O1W|rcsb pdb:5O1X|rcsb pdb:5O1Y|rcsb pdb:5O1Z|rcsb pdb:5O20|rcsb pdb:6GC3|rcsb pdb:6O3W|rcsb pdb:6O3X|rcsb pdb:6O3Y|refseq:NP_014148.1|sgd:S000005195|mint:P53617|dip:DIP-6778N|sgd:YNL251C(identity)	-	-	crc64:75082BDB0C42AE37	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Ediu0oNiZ/+YVY8l3fNdgP5A+v09606	rogid:FJJxQtZfVVwYERLXtGkq6cJ9I1U559292	intact-crc:B76C74B91D286FC1|rigid:EsLaDP+DGoWArV+Xn93wox8hmZs	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P53829	uniprotkb:P13196	intact:EBI-28306|uniprotkb:D6W0Q5|ensemblfungi:YNL288W	intact:EBI-3905054|ensembl:ENSP00000309259|ensembl:ENSP00000378416|ensembl:ENSP00000417719|ensembl:ENSP00000418779	psi-mi:caf40_yeast(display_long)|uniprotkb:YNL288W(locus name)|uniprotkb:N0540(orf name)|uniprotkb:40 kDa CCR4-associated factor(gene name synonym)|uniprotkb:CAF40(gene name)|psi-mi:CAF40(display_short)	psi-mi:hem1_human(display_long)|uniprotkb:ALAS1(gene name)|psi-mi:ALAS1(display_short)|uniprotkb:ALAS3(gene name synonym)|uniprotkb:ALASH(gene name synonym)|uniprotkb:5-aminolevulinic acid synthase 1(gene name synonym)|uniprotkb:Delta-ALA synthase 1(gene name synonym)|uniprotkb:Delta-aminolevulinate synthase 1(gene name synonym)|uniprotkb:OK/SW-cl.121(orf name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11533608|imex:IM-24995-1178	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014111.1|sgd:S000005232|dip:DIP-1995N|mint:P53829|ensemblfungi:YNL288W(gene)|ensemblfungi:YNL288W_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR007216(Cell differentiation, Rcd1-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:4CV5|sgd:YNL288W(identity)	refseq:NP_001291372.1|refseq:NP_001291373.1|refseq:NP_000679.1|refseq:NP_954635.1|go:"GO:0006783"(heme biosynthetic process)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0042541"(hemoglobin biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0048821"(erythrocyte development)|ensembl:ENSG00000023330(gene)|ensembl:ENST00000310271(transcript)|ensembl:ENST00000394965(transcript)|ensembl:ENST00000469224(transcript)|ensembl:ENST00000484952(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0003870"(5-aminolevulinate synthase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|interpro:IPR001917(Aminotransferase, class-II, pyridoxal-phosphate binding site)|interpro:IPR004839(Aminotransferase, class I and II)|interpro:IPR010961(Tetrapyrrole biosynthesis, 5-aminolevulinic acid synthase)|interpro:IPR015118(5-aminolevulinate synthase presequence)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|mint:P13196|reactome:R-HSA-189451|reactome:R-HSA-1989781|reactome:R-HSA-2151201|go:"GO:0006782"(protoporphyrinogen IX biosynthetic process)|entrezgene/locuslink:211(identity)	-	crc64:F3DBABE6AD3C7F3C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:etuSSgFGQOcgxPDexEXUqQg6H5s559292	rogid:HFjJ6zrRF9UYD7LMB6A3CcxcS7c9606	intact-crc:B5410FE9BC3C27B2|rigid:veJNsWE3nerBonQco5aUGJc24Cg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P53829	uniprotkb:P37198	intact:EBI-28306|uniprotkb:D6W0Q5|ensemblfungi:YNL288W	intact:EBI-347978|intact:EBI-28983799|ensembl:ENSP00000305503|ensembl:ENSP00000407331|ensembl:ENSP00000471191|ensembl:ENSP00000473192|uniprotkb:Q6GTM2|uniprotkb:Q503A4|uniprotkb:Q96C43|uniprotkb:Q9NSL1|uniprotkb:B3KWU5	psi-mi:caf40_yeast(display_long)|uniprotkb:YNL288W(locus name)|uniprotkb:N0540(orf name)|uniprotkb:40 kDa CCR4-associated factor(gene name synonym)|uniprotkb:CAF40(gene name)|psi-mi:CAF40(display_short)	psi-mi:nup62_human(display_long)|uniprotkb:NUP62(gene name)|psi-mi:NUP62(display_short)|uniprotkb:62 kDa nucleoporin(gene name synonym)|uniprotkb:Nucleoporin Nup62(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11533635|imex:IM-24995-1181	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014111.1|sgd:S000005232|dip:DIP-1995N|mint:P53829|ensemblfungi:YNL288W(gene)|ensemblfungi:YNL288W_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR007216(Cell differentiation, Rcd1-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:4CV5|sgd:YNL288W(identity)	refseq:NP_714941.1|ensembl:ENSG00000213024(gene)|ensembl:ENST00000352066(transcript)|ensembl:ENST00000422090(transcript)|ensembl:ENST00000596217(transcript)|ensembl:ENST00000597029(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005642"(annulate lamellae)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007100"(mitotic centrosome separation)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007569"(cell aging)|go:"GO:0008219"(cell death)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0003682"(chromatin binding)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0019894"(kinesin binding)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042306"(regulation of protein import into nucleus)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043069"(negative regulation of programmed cell death)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045742"(positive regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046578"(regulation of Ras protein signal transduction)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0046601"(positive regulation of centriole replication)|go:"GO:0051028"(mRNA transport)|go:"GO:0051425"(PTB domain binding)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0072686"(mitotic spindle)|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|go:"GO:0090543"(Flemming body)|go:"GO:0098534"(centriole assembly)|go:"GO:1903438"(positive regulation of mitotic cytokinetic process)|go:"GO:1904781"(positive regulation of protein localization to centrosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR007758(Nucleoporin, Nsp1-like, C-terminal)|interpro:IPR026010|interpro:IPR033072|mint:P37198|rcsb pdb:2H4D|rcsb pdb:5IJN|rcsb pdb:5IJO|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|refseq:NP_714940.1|refseq:NP_001180286.1|refseq:NP_036478.2|refseq:NP_057637.2|ensembl:ENSP00000305503|ensembl:ENSP00000407331|ensembl:ENSP00000471191|ensembl:ENSP00000473192|dip:DIP-29749N|entrezgene/locuslink:23636(identity)	-	crc64:F3DBABE6AD3C7F3C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:etuSSgFGQOcgxPDexEXUqQg6H5s559292	rogid:v7mvKvTtVEnLMwcpUZIcdAzge009606	intact-crc:48BF0748BA1A8EA9|rigid:0qAntt6PSBiPdBfSNgOEoe/3fxI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P53829	uniprotkb:P32321	intact:EBI-28306|uniprotkb:D6W0Q5|ensemblfungi:YNL288W	intact:EBI-739870|uniprotkb:Q9BVD8|uniprotkb:B2R836|uniprotkb:Q5M7Z8|uniprotkb:D3DP49|uniprotkb:D3DP50|ensembl:ENSP00000398194|ensembl:ENSP00000424017	psi-mi:caf40_yeast(display_long)|uniprotkb:YNL288W(locus name)|uniprotkb:N0540(orf name)|uniprotkb:40 kDa CCR4-associated factor(gene name synonym)|uniprotkb:CAF40(gene name)|psi-mi:CAF40(display_short)	psi-mi:dctd_human(display_long)|uniprotkb:DCTD(gene name)|psi-mi:DCTD(display_short)|uniprotkb:dCMP deaminase(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11533626|imex:IM-24995-1180	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014111.1|sgd:S000005232|dip:DIP-1995N|mint:P53829|ensemblfungi:YNL288W(gene)|ensemblfungi:YNL288W_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR007216(Cell differentiation, Rcd1-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:4CV5|sgd:YNL288W(identity)	refseq:NP_001012750.1|refseq:NP_001912.2|ensembl:ENSG00000129187(gene)|ensembl:ENST00000438320(transcript)|ensembl:ENST00000510370(transcript)|go:"GO:0004132"(dCMP deaminase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006220"(pyrimidine nucleotide metabolic process)|go:"GO:0006226"(dUMP biosynthetic process)|go:"GO:0006231"(dTMP biosynthetic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR002125(CMP/dCMP deaminase, zinc-binding)|interpro:IPR015517(Cytidine deaminase)|interpro:IPR016192(APOBEC/CMP deaminase, zinc-binding)|interpro:IPR016193(Cytidine deaminase-like)|interpro:IPR016473(dCMP deaminase)|interpro:IPR035105|mint:P32321|rcsb pdb:2W4L|reactome:R-HSA-499943|refseq:XP_005262836.1|refseq:XP_005262837.1|refseq:XP_011529976.1|refseq:XP_016863305.1|refseq:XP_016863306.1|refseq:XP_016863307.1|refseq:XP_016863308.1|refseq:XP_016863309.1|refseq:XP_016863310.1|refseq:XP_016863311.1|entrezgene/locuslink:1635(identity)	-	crc64:F3DBABE6AD3C7F3C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:etuSSgFGQOcgxPDexEXUqQg6H5s559292	rogid:lU3gEi7XdIJbuPlMkForbVKEOyY9606	intact-crc:D206E2575063FD9F|rigid:AxSpZw9n6xa4SlD4PHm1ExQ6IVs	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P53829	uniprotkb:P14136	intact:EBI-28306|uniprotkb:D6W0Q5|ensemblfungi:YNL288W	intact:EBI-744302|uniprotkb:Q53H98|uniprotkb:Q5D055|uniprotkb:Q6ZQS3|uniprotkb:Q7Z5J6|uniprotkb:Q7Z5J7|uniprotkb:Q96KS4|uniprotkb:Q96P18|uniprotkb:Q9UFD0|uniprotkb:B2RD44|uniprotkb:D3DX59|intact:EBI-3909365|uniprotkb:E9PAX3|ensembl:ENSP00000466598|uniprotkb:A7REI1	psi-mi:caf40_yeast(display_long)|uniprotkb:YNL288W(locus name)|uniprotkb:N0540(orf name)|uniprotkb:40 kDa CCR4-associated factor(gene name synonym)|uniprotkb:CAF40(gene name)|psi-mi:CAF40(display_short)	psi-mi:gfap_human(display_long)|uniprotkb:GFAP(gene name)|psi-mi:GFAP(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11533617|imex:IM-24995-1179	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014111.1|sgd:S000005232|dip:DIP-1995N|mint:P53829|ensemblfungi:YNL288W(gene)|ensemblfungi:YNL288W_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR007216(Cell differentiation, Rcd1-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:4CV5|sgd:YNL288W(identity)	refseq:NP_001124491.1|refseq:NP_001229305.1|refseq:NP_002046.1|ensembl:ENSG00000131095(gene)|ensembl:ENST00000588735(transcript)|go:"GO:0005178"(integrin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0009611"(response to wounding)|go:"GO:0010467"(gene expression)|go:"GO:0010625"(positive regulation of Schwann cell proliferation)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0014002"(astrocyte development)|go:"GO:0019900"(kinase binding)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0031102"(neuron projection regeneration)|go:"GO:0042802"(identical protein binding)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0044297"(cell body)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0051580"(regulation of neurotransmitter uptake)|go:"GO:0060020"(Bergmann glial cell differentiation)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0070779"(D-aspartate import across plasma membrane)|go:"GO:0097450"(astrocyte end-foot)|go:"GO:0098574"(cytoplasmic side of lysosomal membrane)|go:"GO:1904714"(regulation of chaperone-mediated autophagy)|interpro:IPR006821(Intermediate filament, DNA-binding region)|interpro:IPR018039|interpro:IPR027701|interpro:IPR039008|mint:P14136|rcsb pdb:6A9P|reactome:R-HSA-1251985|reactome:R-HSA-9613829|entrezgene/locuslink:2670(identity)	-	crc64:F3DBABE6AD3C7F3C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:etuSSgFGQOcgxPDexEXUqQg6H5s559292	rogid:Pz4JW0WjMjBYILTDSX9jUmMqWhg9606	intact-crc:DD71143743EA5687|rigid:C0lpqj92CSG9FmNjEftjqDxKnp8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P53829	uniprotkb:P00492	intact:EBI-28306|uniprotkb:D6W0Q5|ensemblfungi:YNL288W	intact:EBI-748210|uniprotkb:A6NHF0|uniprotkb:B2R8M9|ensembl:ENSP00000298556	psi-mi:caf40_yeast(display_long)|uniprotkb:YNL288W(locus name)|uniprotkb:N0540(orf name)|uniprotkb:40 kDa CCR4-associated factor(gene name synonym)|uniprotkb:CAF40(gene name)|psi-mi:CAF40(display_short)	psi-mi:hprt_human(display_long)|uniprotkb:HPRT1(gene name)|psi-mi:HPRT1(display_short)|uniprotkb:HPRT(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11533599|imex:IM-24995-1177	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014111.1|sgd:S000005232|dip:DIP-1995N|mint:P53829|ensemblfungi:YNL288W(gene)|ensemblfungi:YNL288W_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR007216(Cell differentiation, Rcd1-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:4CV5|sgd:YNL288W(identity)	refseq:NP_000185.1|ensembl:ENSG00000165704(gene)|ensembl:ENST00000298556(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001913"(T cell mediated cytotoxicity)|go:"GO:0001975"(response to amphetamine)|go:"GO:0004422"(hypoxanthine phosphoribosyltransferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006164"(purine nucleotide biosynthetic process)|go:"GO:0006166"(purine ribonucleoside salvage)|go:"GO:0006168"(adenine salvage)|go:"GO:0006178"(guanine salvage)|go:"GO:0007625"(grooming behavior)|go:"GO:0007626"(locomotory behavior)|go:"GO:0021756"(striatum development)|go:"GO:0021895"(cerebral cortex neuron differentiation)|go:"GO:0021954"(central nervous system neuron development)|go:"GO:0032263"(GMP salvage)|go:"GO:0032264"(IMP salvage)|go:"GO:0042417"(dopamine metabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043103"(hypoxanthine salvage)|go:"GO:0045964"(positive regulation of dopamine metabolic process)|go:"GO:0046038"(GMP catabolic process)|go:"GO:0046040"(IMP metabolic process)|go:"GO:0046100"(hypoxanthine metabolic process)|go:"GO:0046651"(lymphocyte proliferation)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0052657"(guanine phosphoribosyltransferase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000836(Phosphoribosyltransferase)|interpro:IPR005904(Hypoxanthine phosphoribosyl transferase)|interpro:IPR029057|mint:P00492|rcsb pdb:1BZY|rcsb pdb:1D6N|rcsb pdb:1HMP|rcsb pdb:1Z7G|go:"GO:0048813"(dendrite morphogenesis)|rcsb pdb:2VFA|rcsb pdb:3GEP|rcsb pdb:3GGC|rcsb pdb:3GGJ|rcsb pdb:4IJQ|rcsb pdb:4KN6|rcsb pdb:4RAB|rcsb pdb:4RAC|rcsb pdb:4RAD|rcsb pdb:4RAN|rcsb pdb:4RAO|rcsb pdb:4RAQ|rcsb pdb:5BRN|rcsb pdb:5BSK|rcsb pdb:5HIA|rcsb pdb:5W8V|rcsb pdb:6BNJ|reactome:R-HSA-74217|entrezgene/locuslink:3251(identity)	-	crc64:F3DBABE6AD3C7F3C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:etuSSgFGQOcgxPDexEXUqQg6H5s559292	rogid:w87Sv/qOAkHFqJm0vu0Ayqlz7TA9606	intact-crc:634CC87FCCB08FBC|rigid:amwpDhy02cE1/Ha06fNBQk+Smf8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P53829	uniprotkb:Q7Z6G3-2	intact:EBI-28306|uniprotkb:D6W0Q5|ensemblfungi:YNL288W	intact:EBI-10172876|ensembl:ENSP00000457354|intact:EBI-14062040	psi-mi:caf40_yeast(display_long)|uniprotkb:YNL288W(locus name)|uniprotkb:N0540(orf name)|uniprotkb:40 kDa CCR4-associated factor(gene name synonym)|uniprotkb:CAF40(gene name)|psi-mi:CAF40(display_short)	psi-mi:q7z6g3-2(display_long)|uniprotkb:EFCBP2(gene name synonym)|uniprotkb:Neuronal calcium-binding protein 2(gene name synonym)|uniprotkb:Synaptotagmin-interacting protein 2(gene name synonym)|uniprotkb:NECAB2(gene name)|psi-mi:NECAB2(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11533588|imex:IM-24995-1176	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014111.1|sgd:S000005232|dip:DIP-1995N|mint:P53829|ensemblfungi:YNL288W(gene)|ensemblfungi:YNL288W_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR007216(Cell differentiation, Rcd1-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:4CV5|sgd:YNL288W(identity)	ensembl:ENSG00000103154(gene)|ensembl:ENST00000565691(transcript)|uniprotkb:Q7Z6G3-2(isoform-parent)|intact:EBI-950070(isoform-parent)|entrezgene/locuslink:54550(identity)	-	crc64:F3DBABE6AD3C7F3C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:etuSSgFGQOcgxPDexEXUqQg6H5s559292	rogid:4S7oIx6h+mKzV3EPxqcfMNqaNko9606	intact-crc:D2450D635B7DE720|rigid:IDVmdYPY6eAPOqTBtXgJKUh2BfQ	false	-	sufficient binding region:65-303	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P53829	uniprotkb:Q15427	intact:EBI-28306|uniprotkb:D6W0Q5|ensemblfungi:YNL288W	intact:EBI-348469|ensembl:ENSP00000271628|intact:EBI-1047735|uniprotkb:Q5SZ63	psi-mi:caf40_yeast(display_long)|uniprotkb:YNL288W(locus name)|uniprotkb:N0540(orf name)|uniprotkb:40 kDa CCR4-associated factor(gene name synonym)|uniprotkb:CAF40(gene name)|psi-mi:CAF40(display_short)	psi-mi:sf3b4_human(display_long)|uniprotkb:SF3B4(gene name)|psi-mi:SF3B4(display_short)|uniprotkb:SAP49(gene name synonym)|uniprotkb:Spliceosome-associated protein 49(gene name synonym)|uniprotkb:Pre-mRNA-splicing factor SF3b 49 kDa subunit(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11533662|imex:IM-24995-1184	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014111.1|sgd:S000005232|dip:DIP-1995N|mint:P53829|ensemblfungi:YNL288W(gene)|ensemblfungi:YNL288W_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR007216(Cell differentiation, Rcd1-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:4CV5|sgd:YNL288W(identity)	refseq:NP_005841.1|ensembl:ENSG00000143368(gene)|ensembl:ENST00000271628(transcript)|rcsb pdb:6QX9|rcsb pdb:6Y53|rcsb pdb:6Y5Q|rcsb pdb:7ABG|rcsb pdb:7ABH|rcsb pdb:7ABI|rcsb pdb:7DVQ|reactome:R-HSA-72163|reactome:R-HSA-72165|rcsb pdb:6AHD|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:1990935"(splicing factor binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034158|go:"GO:0000375"(RNA splicing, via transesterification reactions)|interpro:IPR034159|interpro:IPR035979|mint:Q15427|rcsb pdb:1X5T|rcsb pdb:5GVQ|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|entrezgene/locuslink:10262(identity)	-	crc64:F3DBABE6AD3C7F3C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:etuSSgFGQOcgxPDexEXUqQg6H5s559292	rogid:Jgy6WmBFKkphpZLLte2GgsagUVI9606	intact-crc:C1519033FFDCF390|rigid:dEnI/usfnIkEGrMpac3rNG74SFw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P53829	uniprotkb:Q5D1E8	intact:EBI-28306|uniprotkb:D6W0Q5|ensemblfungi:YNL288W	intact:EBI-747793|uniprotkb:Q6I9Z1|uniprotkb:Q9H5P1|uniprotkb:D3DPT0|ensembl:ENSP00000362179	psi-mi:caf40_yeast(display_long)|uniprotkb:YNL288W(locus name)|uniprotkb:N0540(orf name)|uniprotkb:40 kDa CCR4-associated factor(gene name synonym)|uniprotkb:CAF40(gene name)|psi-mi:CAF40(display_short)	psi-mi:zc12a_human(display_long)|uniprotkb:MCPIP(gene name synonym)|uniprotkb:MCPIP1(gene name synonym)|uniprotkb:ZC3H12A(gene name)|psi-mi:ZC3H12A(display_short)|uniprotkb:Monocyte chemotactic protein-induced protein 1(gene name synonym)|uniprotkb:Regnase-1(gene name synonym)|uniprotkb:Zinc finger CCCH domain-containing protein 12A(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11533671|imex:IM-24995-1185	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014111.1|sgd:S000005232|dip:DIP-1995N|mint:P53829|ensemblfungi:YNL288W(gene)|ensemblfungi:YNL288W_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR007216(Cell differentiation, Rcd1-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:4CV5|sgd:YNL288W(identity)	refseq:NP_079355.2|refseq:NP_001310479.1|ensembl:ENSG00000163874(gene)|ensembl:ENST00000373087(transcript)|go:"GO:0000294"(nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay)|go:"GO:0000932"(P-body)|go:"GO:0001525"(angiogenesis)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0002757"(immune response-activating signal transduction)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0004532"(exoribonuclease activity)|go:"GO:0004540"(ribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007399"(nervous system development)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010656"(negative regulation of muscle cell apoptotic process)|go:"GO:0010884"(positive regulation of lipid storage)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0030154"(cell differentiation)|go:"GO:0030867"(rough endoplasmic reticulum membrane)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032691"(negative regulation of interleukin-1 beta production)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035198"(miRNA binding)|go:"GO:0035613"(RNA stem-loop binding)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042406"(extrinsic component of endoplasmic reticulum membrane)|go:"GO:0043022"(ribosome binding)|go:"GO:0043031"(negative regulation of macrophage activation)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0044828"(negative regulation by host of viral genome replication)|go:"GO:0045019"(negative regulation of nitric oxide biosynthetic process)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051607"(defense response to virus)|go:"GO:0055118"(negative regulation of cardiac muscle contraction)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0090501"(RNA phosphodiester bond hydrolysis)|go:"GO:0090502"(RNA phosphodiester bond hydrolysis, endonucleolytic)|go:"GO:0098586"(cellular response to virus)|go:"GO:1900016"(negative regulation of cytokine production involved in inflammatory response)|go:"GO:1900119"(positive regulation of execution phase of apoptosis)|go:"GO:1901223"(negative regulation of NIK/NF-kappaB signaling)|go:"GO:1903003"(positive regulation of protein deubiquitination)|go:"GO:1903799"(negative regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1903936"(cellular response to sodium arsenite)|go:"GO:1904637"(cellular response to ionomycin)|go:"GO:1990869"(cellular response to chemokine)|go:"GO:2000320"(negative regulation of T-helper 17 cell differentiation)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|go:"GO:2000627"(positive regulation of miRNA catabolic process)|interpro:IPR021869|interpro:IPR040546|interpro:IPR040757|rcsb pdb:3V32|rcsb pdb:3V33|rcsb pdb:3V34|go:"GO:1900745"(positive regulation of p38MAPK cascade)|entrezgene/locuslink:80149(identity)	-	crc64:F3DBABE6AD3C7F3C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:etuSSgFGQOcgxPDexEXUqQg6H5s559292	rogid:3FqqH/XrYjHaa5oJpPXvfYwHKCQ9606	intact-crc:F876C74ED954BD0E|rigid:9PZ5wbTppPaR8VCtVhxWGZzUepo	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P53829	uniprotkb:Q8NDC0	intact:EBI-28306|uniprotkb:D6W0Q5|ensemblfungi:YNL288W	intact:EBI-741424|uniprotkb:Q96BG5|ensembl:ENSP00000378851|ensembl:ENSP00000481882|uniprotkb:B2RDD8	psi-mi:caf40_yeast(display_long)|uniprotkb:YNL288W(locus name)|uniprotkb:N0540(orf name)|uniprotkb:40 kDa CCR4-associated factor(gene name synonym)|uniprotkb:CAF40(gene name)|psi-mi:CAF40(display_short)	psi-mi:missl_human(display_long)|uniprotkb:C14orf32(gene name synonym)|uniprotkb:Mitogen-activated protein kinase 1-interacting protein 1-like(gene name synonym)|uniprotkb:MAPK1IP1L(gene name)|psi-mi:MAPK1IP1L(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11533680|imex:IM-24995-1186	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014111.1|sgd:S000005232|dip:DIP-1995N|mint:P53829|ensemblfungi:YNL288W(gene)|ensemblfungi:YNL288W_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR007216(Cell differentiation, Rcd1-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:4CV5|sgd:YNL288W(identity)	refseq:NP_653179.1|ensembl:ENSG00000168175(gene)|ensembl:ENST00000395468(transcript)|ensembl:ENST00000622254(transcript)|interpro:IPR031653|entrezgene/locuslink:93487(identity)	-	crc64:F3DBABE6AD3C7F3C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:etuSSgFGQOcgxPDexEXUqQg6H5s559292	rogid:CX220vB2TjggPEso5CHNUVzl79g9606	intact-crc:E23E762ACD478DDF|rigid:omG8K9P74/OnVxCpgI4sniKFvzE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P53829	uniprotkb:Q8WWB3	intact:EBI-28306|uniprotkb:D6W0Q5|ensemblfungi:YNL288W	intact:EBI-740680|ensembl:ENSP00000361276|ensembl:ENSP00000361278|ensembl:ENSP00000402890|uniprotkb:Q5QP03|uniprotkb:Q5QP04|uniprotkb:Q6WNP4|uniprotkb:Q6ZU87|uniprotkb:A8K927	psi-mi:caf40_yeast(display_long)|uniprotkb:YNL288W(locus name)|uniprotkb:N0540(orf name)|uniprotkb:40 kDa CCR4-associated factor(gene name synonym)|uniprotkb:CAF40(gene name)|psi-mi:CAF40(display_short)	psi-mi:dydc1_human(display_long)|uniprotkb:DYDC1(gene name)|psi-mi:DYDC1(display_short)|uniprotkb:DPY30D1(gene name synonym)|uniprotkb:RSD9(orf name)|uniprotkb:RSD-9(orf name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11533689|imex:IM-24995-1187	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014111.1|sgd:S000005232|dip:DIP-1995N|mint:P53829|ensemblfungi:YNL288W(gene)|ensemblfungi:YNL288W_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR007216(Cell differentiation, Rcd1-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:4CV5|sgd:YNL288W(identity)	refseq:NP_620167.1|ensembl:ENSG00000170788(gene)|ensembl:ENST00000372202(transcript)|ensembl:ENST00000372204(transcript)|ensembl:ENST00000421924(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0006348"|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|interpro:IPR007858(Dpy-30)|interpro:IPR037856|refseq:XP_011537636.1|refseq:XP_011537637.1|refseq:NP_001255982.1|refseq:XP_005269606.1|refseq:XP_005269607.1|entrezgene/locuslink:143241(identity)	-	crc64:F3DBABE6AD3C7F3C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:etuSSgFGQOcgxPDexEXUqQg6H5s559292	rogid:W6GUazYFXZGHGijUBpAJ5GiRuXA9606	intact-crc:708DCAABB6113322|rigid:3uApgK1+ckwOYgj1xkBsy5HP/P4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P53829	uniprotkb:Q96IK5	intact:EBI-28306|uniprotkb:D6W0Q5|ensemblfungi:YNL288W	intact:EBI-2548508|ensembl:ENSP00000282570|uniprotkb:Q9H826|uniprotkb:Q9H8V7|uniprotkb:Q9H927	psi-mi:caf40_yeast(display_long)|uniprotkb:YNL288W(locus name)|uniprotkb:N0540(orf name)|uniprotkb:40 kDa CCR4-associated factor(gene name synonym)|uniprotkb:CAF40(gene name)|psi-mi:CAF40(display_short)	psi-mi:gmcl1_human(display_long)|uniprotkb:GMCL1(gene name)|psi-mi:GMCL1(display_short)|uniprotkb:GCL(gene name synonym)|uniprotkb:BTBD13(gene name synonym)|uniprotkb:SPATA29(gene name synonym)|uniprotkb:Spermatogenesis-associated protein 29(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11533698|imex:IM-24995-1188	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014111.1|sgd:S000005232|dip:DIP-1995N|mint:P53829|ensemblfungi:YNL288W(gene)|ensemblfungi:YNL288W_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR007216(Cell differentiation, Rcd1-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:4CV5|sgd:YNL288W(identity)	ensembl:ENSG00000087338(gene)|ensembl:ENST00000282570(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0007281"(germ cell development)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016363"(nuclear matrix)|go:"GO:0042802"(identical protein binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR043380|refseq:NP_848526.1|entrezgene/locuslink:64395(identity)	-	crc64:F3DBABE6AD3C7F3C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:etuSSgFGQOcgxPDexEXUqQg6H5s559292	rogid:ED8yqySVu7BWxpw3DUSNBZSQWrk9606	intact-crc:70355F79BF19CFF1|rigid:9+9FWWtCkFBRiYY6flmnSQGpyz4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P53829	uniprotkb:P42575	intact:EBI-28306|uniprotkb:D6W0Q5|ensemblfungi:YNL288W	intact:EBI-520342|ensembl:ENSP00000312664|uniprotkb:P42576|uniprotkb:D3DXD6|uniprotkb:Q59F21|uniprotkb:Q7KZL6|uniprotkb:Q86UJ3|uniprotkb:Q9BUP7|uniprotkb:Q9BZK9|uniprotkb:A8K5F9|uniprotkb:E9PDN0|uniprotkb:Q9BZL0	psi-mi:caf40_yeast(display_long)|uniprotkb:YNL288W(locus name)|uniprotkb:N0540(orf name)|uniprotkb:40 kDa CCR4-associated factor(gene name synonym)|uniprotkb:CAF40(gene name)|psi-mi:CAF40(display_short)	psi-mi:casp2_human(display_long)|uniprotkb:Protease ICH-1(gene name synonym)|uniprotkb:Neural precursor cell expressed developmentally down-regulated protein 2(gene name synonym)|uniprotkb:CASP2(gene name)|psi-mi:CASP2(display_short)|uniprotkb:ICH1(gene name synonym)|uniprotkb:NEDD2(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11533644|imex:IM-24995-1182	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014111.1|sgd:S000005232|dip:DIP-1995N|mint:P53829|ensemblfungi:YNL288W(gene)|ensemblfungi:YNL288W_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR007216(Cell differentiation, Rcd1-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:4CV5|sgd:YNL288W(identity)	ensembl:ENSG00000106144(gene)|ensembl:ENST00000310447(transcript)|go:"GO:0001554"(luteolysis)|go:"GO:0003407"(neural retina development)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0007420"(brain development)|go:"GO:0007568"(aging)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0016020"(membrane)|go:"GO:0016485"(protein processing)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0035234"(ectopic germ cell programmed cell death)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0097153"(cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0097192"(extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:0097194"(execution phase of apoptosis)|go:"GO:0097199"(cysteine-type endopeptidase activity involved in apoptotic signaling pathway)|go:"GO:0097200"(cysteine-type endopeptidase activity involved in execution phase of apoptosis)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR001309(Peptidase C14, ICE, catalytic subunit p20)|interpro:IPR001315(Caspase Recruitment)|interpro:IPR002138(Peptidase C14, caspase non-catalytic subunit p10)|interpro:IPR002398(Peptidase C14, caspase precursor p45)|interpro:IPR011029(DEATH-like)|interpro:IPR015917(Peptidase C14, caspase precursor p45, core)|interpro:IPR016129(Peptidase C14, ICE, catalytic subunit p20, active site)|interpro:IPR029030|interpro:IPR033139|interpro:IPR035702|rcsb pdb:1PYO|rcsb pdb:2P2C|rcsb pdb:3R5J|rcsb pdb:3R6G|rcsb pdb:3R6L|rcsb pdb:3R7B|rcsb pdb:3R7N|refseq:NP_001215.1|refseq:NP_116764.2|refseq:NP_116765.2|rcsb pdb:3R7S|rcsb pdb:3RJM|rcsb pdb:6GKF|rcsb pdb:6GKG|rcsb pdb:6S9K|rcsb pdb:6SAD|rcsb pdb:6Y8B|rcsb pdb:6Y8D|reactome:R-HSA-168638|reactome:R-HSA-205025|reactome:R-HSA-6803207|entrezgene/locuslink:835(identity)	-	crc64:F3DBABE6AD3C7F3C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:etuSSgFGQOcgxPDexEXUqQg6H5s559292	rogid:3WFvmDoYbW3J84Yd9RVGAOcR8ig9606	intact-crc:4F06FF746585618C|rigid:Ygl8eQbfjHfmfuTNoP01Z9Rqj1U	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P53829	uniprotkb:P53992	intact:EBI-28306|uniprotkb:D6W0Q5|ensemblfungi:YNL288W	intact:EBI-81134|uniprotkb:Q8WV25|ensembl:ENSP00000321845|ensembl:ENSP00000343405|uniprotkb:B4DZT4	psi-mi:caf40_yeast(display_long)|uniprotkb:YNL288W(locus name)|uniprotkb:N0540(orf name)|uniprotkb:40 kDa CCR4-associated factor(gene name synonym)|uniprotkb:CAF40(gene name)|psi-mi:CAF40(display_short)	psi-mi:sc24c_human(display_long)|uniprotkb:SEC24C(gene name)|psi-mi:SEC24C(display_short)|uniprotkb:KIAA0079(gene name synonym)|uniprotkb:SEC24-related protein C(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11533653|imex:IM-24995-1183	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014111.1|sgd:S000005232|dip:DIP-1995N|mint:P53829|ensemblfungi:YNL288W(gene)|ensemblfungi:YNL288W_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR007216(Cell differentiation, Rcd1-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:4CV5|sgd:YNL288W(identity)	go:"GO:0090110"(COPII-coated vesicle cargo loading)|go:"GO:0070971"(endoplasmic reticulum exit site)|interpro:IPR006895(Zinc finger, Sec23/Sec24-type)|interpro:IPR006896(Sec23/Sec24 trunk region)|interpro:IPR006900(Sec23/Sec24 helical region)|interpro:IPR007123(Gelsolin region)|interpro:IPR012990(Sec23/Sec24 beta-sandwich)|interpro:IPR029006|interpro:IPR036174|interpro:IPR036175|interpro:IPR036180|interpro:IPR036465|interpro:IPR041742|mint:P53992|rcsb pdb:3EH2|rcsb pdb:6PU1|reactome:R-HSA-1655829|reactome:R-HSA-204005|reactome:R-HSA-2132295|reactome:R-HSA-983170|reactome:R-HSA-5694530|ensembl:ENSG00000176986(gene)|ensembl:ENST00000339365(transcript)|ensembl:ENST00000345254(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0008270"(zinc ion binding)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0030127"(COPII vesicle coat)|refseq:NP_004913.2|refseq:NP_940999.1|dip:DIP-30981N|entrezgene/locuslink:9632(identity)	-	crc64:F3DBABE6AD3C7F3C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:etuSSgFGQOcgxPDexEXUqQg6H5s559292	rogid:kOKJkIWFOlIpRFLj5JshAGqAg6s9606	intact-crc:5F730E6E7D304BCF|rigid:P4fg5s32kxj2U9SlU+cnA9lU0nE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P53829	uniprotkb:Q9BW62	intact:EBI-28306|uniprotkb:D6W0Q5|ensemblfungi:YNL288W	intact:EBI-743591|uniprotkb:A8K5X4|ensembl:ENSP00000369989|ensembl:ENSP00000369991	psi-mi:caf40_yeast(display_long)|uniprotkb:YNL288W(locus name)|uniprotkb:N0540(orf name)|uniprotkb:40 kDa CCR4-associated factor(gene name synonym)|uniprotkb:CAF40(gene name)|psi-mi:CAF40(display_short)	psi-mi:katl1_human(display_long)|uniprotkb:p60 katanin-like 1(gene name synonym)|uniprotkb:KATNAL1(gene name)|psi-mi:KATNAL1(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11533716|imex:IM-24995-1190	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014111.1|sgd:S000005232|dip:DIP-1995N|mint:P53829|ensemblfungi:YNL288W(gene)|ensemblfungi:YNL288W_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR007216(Cell differentiation, Rcd1-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:4CV5|sgd:YNL288W(identity)	refseq:NP_001014402.1|refseq:NP_115492.1|refseq:XP_005266631.1|ensembl:ENSG00000102781(gene)|ensembl:ENST00000380615(transcript)|ensembl:ENST00000380617(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005874"(microtubule)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008017"(microtubule binding)|go:"GO:0008568"(microtubule-severing ATPase activity)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016853"(isomerase activity)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0042802"(identical protein binding)|go:"GO:0051013"(microtubule severing)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR027417|interpro:IPR028594|interpro:IPR028596|interpro:IPR041569|rcsb pdb:6B5C|entrezgene/locuslink:84056(identity)	-	crc64:F3DBABE6AD3C7F3C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:etuSSgFGQOcgxPDexEXUqQg6H5s559292	rogid:Usi4KXsvZnNfMOGuWVSz4mfrTaE9606	intact-crc:BA1A811F035403DA|rigid:iztkWzEAJT7OQQ9kuB+uGAcdOOs	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9H9H4	uniprotkb:P53829	intact:EBI-4400866|intact:EBI-28975719|ensembl:ENSP00000267202	intact:EBI-28306|uniprotkb:D6W0Q5|ensemblfungi:YNL288W	psi-mi:vp37b_human(display_long)|uniprotkb:VPS37B(gene name)|psi-mi:VPS37B(display_short)|uniprotkb:ESCRT-I complex subunit VPS37B(gene name synonym)	psi-mi:caf40_yeast(display_long)|uniprotkb:YNL288W(locus name)|uniprotkb:N0540(orf name)|uniprotkb:40 kDa CCR4-associated factor(gene name synonym)|uniprotkb:CAF40(gene name)|psi-mi:CAF40(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11533725|imex:IM-24995-1191	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000267202|refseq:NP_078943.1|ensembl:ENSG00000139722(gene)|ensembl:ENST00000267202(transcript)|go:"GO:0000813"(ESCRT I complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0010008"(endosome membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0030496"(midbody)|go:"GO:0031902"(late endosome membrane)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1902188"(obsolete positive regulation of viral release from host cell)|go:"GO:1903774"(positive regulation of viral budding via host ESCRT complex)|interpro:IPR009851(Modifier of rudimentary, Modr)|interpro:IPR029012|interpro:IPR037202|mint:Q9H9H4|rcsb pdb:6VME|reactome:R-HSA-162588|reactome:R-HSA-174490|reactome:R-HSA-917729|reactome:R-HSA-9610379|reactome:R-HSA-9615710|entrezgene/locuslink:79720(identity)	refseq:NP_014111.1|sgd:S000005232|dip:DIP-1995N|mint:P53829|ensemblfungi:YNL288W(gene)|ensemblfungi:YNL288W_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR007216(Cell differentiation, Rcd1-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:4CV5|sgd:YNL288W(identity)	-	-	crc64:F3DBABE6AD3C7F3C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:dj398+zsegXf+gk9OiSeZAVlmqk9606	rogid:etuSSgFGQOcgxPDexEXUqQg6H5s559292	intact-crc:3AC672E431A07D49|rigid:l24RfhSGwCw99FUchlCxB27/nQY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P53829	uniprotkb:Q9NRG1	intact:EBI-28306|uniprotkb:D6W0Q5|ensemblfungi:YNL288W	intact:EBI-739759|uniprotkb:Q53HA7|uniprotkb:Q59EL9|uniprotkb:Q5VV18|uniprotkb:Q5VV20|uniprotkb:B7Z1Z3|ensembl:ENSP00000318602	psi-mi:caf40_yeast(display_long)|uniprotkb:YNL288W(locus name)|uniprotkb:N0540(orf name)|uniprotkb:40 kDa CCR4-associated factor(gene name synonym)|uniprotkb:CAF40(gene name)|psi-mi:CAF40(display_short)	psi-mi:prdc1_human(display_long)|uniprotkb:PRTFDC1(gene name)|psi-mi:PRTFDC1(display_short)|uniprotkb:HHGP(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11533734|imex:IM-24995-1192	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014111.1|sgd:S000005232|dip:DIP-1995N|mint:P53829|ensemblfungi:YNL288W(gene)|ensemblfungi:YNL288W_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR007216(Cell differentiation, Rcd1-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:4CV5|sgd:YNL288W(identity)	refseq:NP_001269715.1|refseq:NP_064585.1|ensembl:ENSG00000099256(gene)|ensembl:ENST00000320152(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0006166"(purine ribonucleoside salvage)|go:"GO:0042803"(protein homodimerization activity)|interpro:IPR000836(Phosphoribosyltransferase)|interpro:IPR005904(Hypoxanthine phosphoribosyl transferase)|interpro:IPR029057|rcsb pdb:2JBH|entrezgene/locuslink:56952(identity)	-	crc64:F3DBABE6AD3C7F3C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:etuSSgFGQOcgxPDexEXUqQg6H5s559292	rogid:grTZnSalFILRSeeZBjM1mTtF0xo9606	intact-crc:3580C8C037E64415|rigid:djKy/pJTqauRfpWeChUlWsatnr4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9BQY4	uniprotkb:P53829	intact:EBI-372094|uniprotkb:Q9BR00|ensembl:ENSP00000360441	intact:EBI-28306|uniprotkb:D6W0Q5|ensemblfungi:YNL288W	psi-mi:rhxf2_human(display_long)|uniprotkb:RHOXF2(gene name)|psi-mi:RHOXF2(display_short)|uniprotkb:THG1(gene name synonym)|uniprotkb:Paired-like homeobox protein PEPP-2(gene name synonym)|uniprotkb:Testis homeobox gene 1(gene name synonym)|uniprotkb:PEPP2(gene name synonym)	psi-mi:caf40_yeast(display_long)|uniprotkb:YNL288W(locus name)|uniprotkb:N0540(orf name)|uniprotkb:40 kDa CCR4-associated factor(gene name synonym)|uniprotkb:CAF40(gene name)|psi-mi:CAF40(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11533707|imex:IM-24995-1189	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_115887.1|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0042802"(identical protein binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|ensembl:ENSG00000131721(gene)|ensembl:ENST00000371388(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|entrezgene/locuslink:84528(identity)	refseq:NP_014111.1|sgd:S000005232|dip:DIP-1995N|mint:P53829|ensemblfungi:YNL288W(gene)|ensemblfungi:YNL288W_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR007216(Cell differentiation, Rcd1-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:4CV5|sgd:YNL288W(identity)	-	-	crc64:F3DBABE6AD3C7F3C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:shpgPqf80gNt+gFDv1K+827ELUQ9606	rogid:etuSSgFGQOcgxPDexEXUqQg6H5s559292	intact-crc:1F818E6A89F0CEBB|rigid:cr3njtD9XOdDhbJXnJOvYX9vN0Q	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9NVV9	uniprotkb:P53829	intact:EBI-741515|uniprotkb:Q53FQ1|uniprotkb:Q6IA99|ensembl:ENSP00000254250|uniprotkb:A6NCB6|uniprotkb:D3DSY5|uniprotkb:H9KV49	intact:EBI-28306|uniprotkb:D6W0Q5|ensemblfungi:YNL288W	psi-mi:thap1_human(display_long)|uniprotkb:THAP1(gene name)|psi-mi:THAP1(display_short)	psi-mi:caf40_yeast(display_long)|uniprotkb:YNL288W(locus name)|uniprotkb:N0540(orf name)|uniprotkb:40 kDa CCR4-associated factor(gene name synonym)|uniprotkb:CAF40(gene name)|psi-mi:CAF40(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11533743|imex:IM-24995-1193	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060575.1|ensembl:ENSG00000131931(gene)|ensembl:ENST00000254250(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001650"(fibrillar center)|go:"GO:0001935"(endothelial cell proliferation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007049"(cell cycle)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016605"(PML body)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR006612(Zinc finger, C2CH-type)|interpro:IPR026516|interpro:IPR038441|mint:Q9NVV9|rcsb pdb:2JTG|rcsb pdb:2KO0|rcsb pdb:2L1G|refseq:NP_945354.1|entrezgene/locuslink:55145(identity)	refseq:NP_014111.1|sgd:S000005232|dip:DIP-1995N|mint:P53829|ensemblfungi:YNL288W(gene)|ensemblfungi:YNL288W_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR007216(Cell differentiation, Rcd1-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:4CV5|sgd:YNL288W(identity)	-	-	crc64:F3DBABE6AD3C7F3C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:/KO90pu5tBnIVq9SMx1JYPXFCEQ9606	rogid:etuSSgFGQOcgxPDexEXUqQg6H5s559292	intact-crc:58CFFF23D302009D|rigid:EOb1ad62YBbD7PDY8Bl/GbqC7i0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96HR9	uniprotkb:P53845	intact:EBI-750345|uniprotkb:Q96LM0|uniprotkb:B2RE01|uniprotkb:A0A1L5BXV3|uniprotkb:D6W5Z0|ensembl:ENSP00000378861	intact:EBI-28230|uniprotkb:D6W0T0|ensemblfungi:YNL263C	psi-mi:reep6_human(display_long)|uniprotkb:Polyposis locus protein 1-like 1(gene name synonym)|uniprotkb:REEP6(gene name)|psi-mi:REEP6(display_short)|uniprotkb:C19orf32(gene name synonym)|uniprotkb:DP1L1(gene name synonym)	psi-mi:yif1_yeast(display_long)|uniprotkb:YNL263C(locus name)|uniprotkb:N0820(orf name)|uniprotkb:YIF1(gene name)|psi-mi:YIF1(display_short)|uniprotkb:YIP1-interacting factor 1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11533781|imex:IM-24995-1197	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_612402.1|refseq:NP_001316485.1|ensembl:ENSG00000115255(gene)|ensembl:ENST00000395479(transcript)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030665"(clathrin-coated vesicle membrane)|go:"GO:0032386"(regulation of intracellular transport)|go:"GO:0050908"(detection of light stimulus involved in visual perception)|interpro:IPR004345(TB2/DP1 and HVA22 related protein)|mint:Q96HR9|reactome:R-HSA-381753|go:"GO:0005634"(nucleus)|entrezgene/locuslink:92840(identity)	refseq:NP_014136.1|sgd:S000005207|dip:DIP-1729N|ensemblfungi:YNL263C(gene)|ensemblfungi:YNL263C_mRNA(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0015031"(protein transport)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0030173"(integral component of Golgi membrane)|interpro:IPR005578(Hrf1)|sgd:YNL263C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2017/05/05	rogid:pB8AjjNTpmaaLJ8j7MCBM45UAHE9606	rogid:HEs4ZRFWRAkXinwmuLiWGpmUqsM559292	intact-crc:43A926EC8E5F027F|rigid:NrYeqeWFOpq/h3AvUoDJC6WdpbE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:A0A024R4Q5	uniprotkb:P53900	intact:EBI-11527449	intact:EBI-13246|uniprotkb:D6W130|ensemblfungi:YNL153C	psi-mi:a0a024r4q5_human(display_long)|uniprotkb:hCG_20946(orf name)|uniprotkb:TFPT(gene name)|psi-mi:TFPT(display_short)	psi-mi:pfd4_yeast(display_long)|uniprotkb:GIM3(gene name)|psi-mi:GIM3(display_short)|uniprotkb:PFD4(gene name synonym)|uniprotkb:YNL153C(locus name)|uniprotkb:N1761(orf name)|uniprotkb:Genes involved in microtubule biogenesis protein 3(gene name synonym)|uniprotkb:Gim complex subunit 3(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11533790|imex:IM-24995-1198	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_037474.1|interpro:IPR033555|go:"GO:0005654"(nucleoplasm)|go:"GO:0006915"(apoptotic process)|entrezgene/locuslink:29844(identity)	refseq:NP_014246.1|sgd:S000005097|mint:P53900|dip:DIP-3000N|ensemblfungi:YNL153C(gene)|ensemblfungi:YNL153C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:0015631"(tubulin binding)|go:"GO:0016272"(prefoldin complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0071629"(cytoplasm protein quality control by the ubiquitin-proteasome system)|interpro:IPR002777(Prefoldin beta-like)|interpro:IPR009053(Prefoldin)|interpro:IPR016661(Prefoldin, subunit 4)|sgd:YNL153C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:juI/3gZemjc0hnXDJ9J+bIQ9pBw9606	rogid:TdRDErsc5xwqaEqpI4SSCW0sCsg559292	intact-crc:82D9B7B3C167A792|rigid:1lexydUUIaNmP+up2nXxHIJg2AE	false	sufficient binding region:10-253	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P53845	uniprotkb:Q15041	intact:EBI-28230|uniprotkb:D6W0T0|ensemblfungi:YNL263C	intact:EBI-714543|ensembl:ENSP00000306788|uniprotkb:B7Z6S5|uniprotkb:B7Z791|uniprotkb:F5GXP4	psi-mi:yif1_yeast(display_long)|uniprotkb:YNL263C(locus name)|uniprotkb:N0820(orf name)|uniprotkb:YIF1(gene name)|psi-mi:YIF1(display_short)|uniprotkb:YIP1-interacting factor 1(gene name synonym)	psi-mi:ar6p1_human(display_long)|uniprotkb:ARL6IP(gene name synonym)|uniprotkb:ARL6IP1(gene name)|psi-mi:ARL6IP1(display_short)|uniprotkb:KIAA0069(gene name synonym)|uniprotkb:ARMER(gene name synonym)|uniprotkb:Apoptotic regulator in the membrane of the endoplasmic reticulum(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11533772|imex:IM-24995-1196	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014136.1|sgd:S000005207|dip:DIP-1729N|ensemblfungi:YNL263C(gene)|ensemblfungi:YNL263C_mRNA(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0015031"(protein transport)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0030173"(integral component of Golgi membrane)|interpro:IPR005578(Hrf1)|sgd:YNL263C(identity)	refseq:NP_055976.1|ensembl:ENSG00000170540(gene)|ensembl:ENST00000304414(transcript)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006613"(cotranslational protein targeting to membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0071787"(endoplasmic reticulum tubular network formation)|go:"GO:1903371"(regulation of endoplasmic reticulum tubular network organization)|go:"GO:1990809"(endoplasmic reticulum tubular network membrane organization)|interpro:IPR033301|mint:Q15041|go:"GO:0002038"(positive regulation of L-glutamate import across plasma membrane)|refseq:NP_001300787.1|entrezgene/locuslink:23204(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:HEs4ZRFWRAkXinwmuLiWGpmUqsM559292	rogid:3fjkoyvUx25po7xsPcXgpjEeLJg9606	intact-crc:7E4928BB78B26B7D|rigid:8t8aGnhVCEYy1sCcPsi+mIFoPcw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P53833	uniprotkb:O95273	intact:EBI-13638|uniprotkb:D6W0R2|ensemblfungi:YNL282W	intact:EBI-748961|uniprotkb:A8K3Q0|uniprotkb:A8K3U2|uniprotkb:Q6ZQN9|uniprotkb:Q7Z519|uniprotkb:Q8NBS7|uniprotkb:Q8NBY2|uniprotkb:Q9NS19|uniprotkb:Q9NYH3|uniprotkb:Q9UHX9|ensembl:ENSP00000300213	psi-mi:pop3_yeast(display_long)|uniprotkb:POP3(gene name)|psi-mi:POP3(display_short)|uniprotkb:YNL282W(locus name)|uniprotkb:N0586(orf name)|uniprotkb:RNA-processing protein POP3(gene name synonym)|uniprotkb:RNases MRP/P 22.6 kDa subunit(gene name synonym)	psi-mi:ccdb1_human(display_long)|uniprotkb:Grap2 and cyclin-D-interacting protein(gene name synonym)|uniprotkb:Human homolog of Maid(gene name synonym)|uniprotkb:CCNDBP1(gene name)|psi-mi:CCNDBP1(display_short)|uniprotkb:DIP1(gene name synonym)|uniprotkb:GCIP(gene name synonym)|uniprotkb:HHM(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11533763|imex:IM-24995-1195	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YNL282W(gene)|refseq:NP_014117.1|sgd:S000005226|ensemblfungi:YNL282W_mRNA(transcript)|go:"GO:0000172"(ribonuclease MRP complex)|go:"GO:0000294"(nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay)|go:"GO:0005634"(nucleus)|go:"GO:0005655"(nucleolar ribonuclease P complex)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0008033"(tRNA processing)|go:"GO:0034965"(intronic box C/D RNA processing)|go:"GO:0090502"(RNA phosphodiester bond hydrolysis, endonucleolytic)|interpro:IPR013241(RNase P, subunit Pop3)|rcsb pdb:6AGB|rcsb pdb:6AH3|rcsb pdb:7C79|rcsb pdb:7C7A|mint:P53833|dip:DIP-4997N|sgd:YNL282W(identity)	refseq:NP_036274.3|ensembl:ENSG00000166946(gene)|ensembl:ENST00000300213(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0016604"(nuclear body)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR026907|mint:O95273|rcsb pdb:3AY5|entrezgene/locuslink:23582(identity)	-	crc64:5091EE590BDBCBEA	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:t1z4FYhAJbd9swpeZ8/+rqxgKyk559292	rogid:Vi9aoFc+Mov6P3X6KGmsTxXqxvM9606	intact-crc:6810A1E1E2FBD8E3|rigid:c3J1i2AwKwN4hlWp3i+QGshpy4g	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P53829	uniprotkb:Q9Y2J4	intact:EBI-28306|uniprotkb:D6W0Q5|ensemblfungi:YNL288W	intact:EBI-746752|intact:EBI-28986657|ensembl:ENSP00000409999|uniprotkb:Q53EP1|uniprotkb:Q96F99|uniprotkb:Q9UKB4|uniprotkb:A8K6F1|uniprotkb:B7Z5Q1|uniprotkb:E9PHW3	psi-mi:caf40_yeast(display_long)|uniprotkb:YNL288W(locus name)|uniprotkb:N0540(orf name)|uniprotkb:40 kDa CCR4-associated factor(gene name synonym)|uniprotkb:CAF40(gene name)|psi-mi:CAF40(display_short)	psi-mi:amol2_human(display_long)|uniprotkb:Leman coiled-coil protein(gene name synonym)|uniprotkb:AMOTL2(gene name)|psi-mi:AMOTL2(display_short)|uniprotkb:KIAA0989(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11533752|imex:IM-24995-1194	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014111.1|sgd:S000005232|dip:DIP-1995N|mint:P53829|ensemblfungi:YNL288W(gene)|ensemblfungi:YNL288W_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR007216(Cell differentiation, Rcd1-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:4CV5|sgd:YNL288W(identity)	refseq:NP_001265612.1|refseq:NP_001265614.1|ensembl:ENSG00000114019(gene)|refseq:XP_006713717.1|refseq:NP_057285.3|refseq:XP_011511183.1|ensembl:ENST00000422605(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0003365"(establishment of cell polarity involved in ameboidal cell migration)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0035329"(hippo signaling)|go:"GO:0055037"(recycling endosome)|interpro:IPR009114(Angiomotin)|interpro:IPR024646|mint:Q9Y2J4|reactome:R-HSA-2028269|refseq:XP_016862069.1|refseq:XP_016862070.1|refseq:XP_016862071.1|ensembl:ENST00000249883|ensembl:ENSP00000249883|ensembl:ENSP00000409999|ensembl:ENST00000513145|ensembl:ENSP00000425475|ensembl:ENST00000514516|ensembl:ENSP00000424765|dip:DIP-57510N|entrezgene/locuslink:51421(identity)	-	crc64:F3DBABE6AD3C7F3C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:etuSSgFGQOcgxPDexEXUqQg6H5s559292	rogid:SHtKAcLLnTpSSLwVE7yQ1WECoZk9606	intact-crc:9A0BC6D8FCDB0C19|rigid:wL97b/N7Zx3p3qCYb4ZACTiLgkw	false	-	sufficient binding region:314-779	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P53900	uniprotkb:P43365	intact:EBI-13246|uniprotkb:D6W130|ensemblfungi:YNL153C	intact:EBI-749530|uniprotkb:Q9NSD3|intact:EBI-10178394|uniprotkb:Q6FHH8|ensembl:ENSP00000350592|ensembl:ENSP00000377447|ensembl:ENSP00000377478	psi-mi:pfd4_yeast(display_long)|uniprotkb:GIM3(gene name)|psi-mi:GIM3(display_short)|uniprotkb:PFD4(gene name synonym)|uniprotkb:YNL153C(locus name)|uniprotkb:N1761(orf name)|uniprotkb:Genes involved in microtubule biogenesis protein 3(gene name synonym)|uniprotkb:Gim complex subunit 3(gene name synonym)	psi-mi:magac_human(display_long)|uniprotkb:MAGE-12 antigen(gene name synonym)|uniprotkb:MAGE12F antigen(gene name synonym)|uniprotkb:Cancer/testis antigen 1.12(gene name synonym)|uniprotkb:MAGEA12(gene name)|psi-mi:MAGEA12(display_short)|uniprotkb:MAGE12(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11533801|imex:IM-24995-1199	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014246.1|sgd:S000005097|mint:P53900|dip:DIP-3000N|ensemblfungi:YNL153C(gene)|ensemblfungi:YNL153C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:0015631"(tubulin binding)|go:"GO:0016272"(prefoldin complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0071629"(cytoplasm protein quality control by the ubiquitin-proteasome system)|interpro:IPR002777(Prefoldin beta-like)|interpro:IPR009053(Prefoldin)|interpro:IPR016661(Prefoldin, subunit 4)|sgd:YNL153C(identity)	refseq:NP_001159858.1|refseq:NP_001159859.1|refseq:NP_005358.2|ensembl:ENSG00000213401(gene)|ensembl:ENST00000357916(transcript)|ensembl:ENST00000393869(transcript)|ensembl:ENST00000393900(transcript)|interpro:IPR002190(MAGE protein)|interpro:IPR021072|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|entrezgene/locuslink:4111(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:TdRDErsc5xwqaEqpI4SSCW0sCsg559292	rogid:3/Jxz2VsFOb67RWqWj3xbTrw3s49606	intact-crc:03DAEDC8A026E4D5|rigid:EPAg9IMHONr/O35Snf2Pkb3nT7k	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12800	uniprotkb:P53900	intact:EBI-717422|uniprotkb:Q12801|uniprotkb:Q9UD77|uniprotkb:A8K5E9|uniprotkb:Q9UD75|ensembl:ENSP00000257915	intact:EBI-13246|uniprotkb:D6W130|ensemblfungi:YNL153C	psi-mi:tfcp2_human(display_long)|uniprotkb:Transcription factor LSF(gene name synonym)|uniprotkb:SAA3 enhancer factor(gene name synonym)|uniprotkb:TFCP2(gene name)|psi-mi:TFCP2(display_short)|uniprotkb:LSF(gene name synonym)|uniprotkb:SEF(gene name synonym)	psi-mi:pfd4_yeast(display_long)|uniprotkb:GIM3(gene name)|psi-mi:GIM3(display_short)|uniprotkb:PFD4(gene name synonym)|uniprotkb:YNL153C(locus name)|uniprotkb:N1761(orf name)|uniprotkb:Genes involved in microtubule biogenesis protein 3(gene name synonym)|uniprotkb:Gim complex subunit 3(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11533810|imex:IM-24995-1200	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001166923.1|refseq:NP_001166924.1|refseq:NP_005644.2|ensembl:ENSG00000135457(gene)|ensembl:ENST00000257915(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR007604(CP2 transcription factor)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR037599|interpro:IPR041418|mint:Q12800|entrezgene/locuslink:7024(identity)	refseq:NP_014246.1|sgd:S000005097|mint:P53900|dip:DIP-3000N|ensemblfungi:YNL153C(gene)|ensemblfungi:YNL153C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:0015631"(tubulin binding)|go:"GO:0016272"(prefoldin complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0071629"(cytoplasm protein quality control by the ubiquitin-proteasome system)|interpro:IPR002777(Prefoldin beta-like)|interpro:IPR009053(Prefoldin)|interpro:IPR016661(Prefoldin, subunit 4)|sgd:YNL153C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:M7mQ08NDYxuawmUEKRgjSdIr+Og9606	rogid:TdRDErsc5xwqaEqpI4SSCW0sCsg559292	intact-crc:8FBE88F5E374616B|rigid:4kETE+1FpGLf+uZfabdDMW6BF5Y	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P53906	uniprotkb:Q8N6L0	intact:EBI-28943|ensemblfungi:YNL146W|uniprotkb:D6W137	intact:EBI-749265|uniprotkb:Q96MC3|ensembl:ENSP00000404220	psi-mi:yno6_yeast(display_long)|uniprotkb:N1203(orf name)|uniprotkb:N1785(orf name)|uniprotkb:YNL146W(locus name)	psi-mi:kash5_human(display_long)|uniprotkb:KASH5(gene name)|psi-mi:KASH5(display_short)|uniprotkb:CCDC155(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 155(gene name synonym)|uniprotkb:KASH domain-containing protein 5(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11533819|imex:IM-24995-1201	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005090|ensemblfungi:YNL146W(gene)|refseq:NP_014253.3|dip:DIP-8009N|ensemblfungi:YNL146W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|sgd:YNL146W(identity)	refseq:NP_653289.3|ensembl:ENSG00000161609(gene)|ensembl:ENST00000447857(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034397"(telomere localization)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051225"(spindle assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0090172"(microtubule cytoskeleton organization involved in homologous chromosome segregation)|go:"GO:0090220"(chromosome localization to nuclear envelope involved in homologous chromosome segregation)|go:"GO:0090619"(meiotic spindle pole)|interpro:IPR011992(EF-Hand type)|interpro:IPR028168|interpro:IPR028170|interpro:IPR039508|mint:Q8N6L0|rcsb pdb:6R2I|rcsb pdb:6WMF|entrezgene/locuslink:147872(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:SvwjVFPBttBj4iLtjQSzRM4+w+E559292	rogid:Wl9L7AcvDHCZuKjYLn8QgGIbZTc9606	intact-crc:79D0C8A3E4BC7355|rigid:d3Li+yGLH97Yu1w/g+m3e/WKWPI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96BA8	uniprotkb:P53906	intact:EBI-6942903|ensembl:ENSP00000481956|intact:MINT-268046|intact:MINT-8162577|uniprotkb:Q8N2D5|uniprotkb:Q96CP0	intact:EBI-28943|ensemblfungi:YNL146W|uniprotkb:D6W137	psi-mi:cr3l1_human(display_long)|uniprotkb:CREB3L1(gene name)|psi-mi:CREB3L1(display_short)|uniprotkb:OASIS(gene name synonym)|uniprotkb:PSEC0238(orf name)|uniprotkb:Old astrocyte specifically-induced substance(gene name synonym)	psi-mi:yno6_yeast(display_long)|uniprotkb:N1203(orf name)|uniprotkb:N1785(orf name)|uniprotkb:YNL146W(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11533828|imex:IM-24995-1202	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157613(gene)|ensembl:ENST00000621158(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0070278"(extracellular matrix constituent secretion)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029805|mint:Q96BA8|reactome:R-HSA-8874211|refseq:NP_443086.1|entrezgene/locuslink:90993(identity)	sgd:S000005090|ensemblfungi:YNL146W(gene)|refseq:NP_014253.3|dip:DIP-8009N|ensemblfungi:YNL146W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|sgd:YNL146W(identity)	-	comment:mint|function:"Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE"	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:sMWUFmBeBBCO+T0Y2CuB/un1lBg9606	rogid:SvwjVFPBttBj4iLtjQSzRM4+w+E559292	intact-crc:1973D9862D3CF33E|rigid:/A0HvqM6hwAcrJl7MjWObv4NNjc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P53919	uniprotkb:Q6P1W5	intact:EBI-28887|uniprotkb:B0KZR2|uniprotkb:B0KZS1|uniprotkb:B0KZT9|uniprotkb:B0KZZ3|uniprotkb:B0L002|uniprotkb:D6W159|ensemblfungi:YNL124W	intact:EBI-946029|uniprotkb:B3KVT1|uniprotkb:Q96IC8|ensembl:ENSP00000435634|uniprotkb:D3DPR3|uniprotkb:E9PJ76	psi-mi:naf1_yeast(display_long)|uniprotkb:YNL124W(locus name)|uniprotkb:N1888(orf name)|uniprotkb:NAF1(gene name)|psi-mi:NAF1(display_short)|uniprotkb:Nuclear assembly factor 1(gene name synonym)	psi-mi:ca094_human(display_long)|uniprotkb:C1orf94(gene name)|psi-mi:C1orf94(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11533838|imex:IM-24995-1203	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005068|refseq:NP_014275.3|dip:DIP-4345N|ensemblfungi:YNL124W(gene)|ensemblfungi:YNL124W_mRNA(transcript)|go:"GO:0000493"(box H/ACA snoRNP assembly)|go:"GO:0001522"(pseudouridine synthesis)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005732"("sno(s)RNA-containing ribonucleoprotein complex")|go:"GO:0006364"(rRNA processing)|go:"GO:0042254"(ribosome biogenesis)|interpro:IPR007504(Gar1 protein RNA-binding region)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR038664|interpro:IPR040309|rcsb pdb:2V3M|sgd:YNL124W(identity)	refseq:NP_001128206.1|refseq:NP_116273.2|ensembl:ENSG00000142698(gene)|ensembl:ENST00000488417(transcript)|interpro:IPR031496|entrezgene/locuslink:84970(identity)	-	crc64:5A496278070F6255	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:9ZtegpRDLFL25BUqw4ke9qJ393Q559292	rogid:y1o4xWvTl2CBA1J7jsP7y8ZjLzM9606	intact-crc:37F93C36DC094265|rigid:OrHkMbBJnu8C5r+nNaJaggvPGMs	false	-	sufficient binding region:191-598	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P43365	uniprotkb:P53923	intact:EBI-749530|uniprotkb:Q9NSD3|intact:EBI-10178394|uniprotkb:Q6FHH8|ensembl:ENSP00000350592|ensembl:ENSP00000377447|ensembl:ENSP00000377478	intact:EBI-28871|uniprotkb:B0KZW1|uniprotkb:B0L006|uniprotkb:Q66R25|uniprotkb:B0KZR6|uniprotkb:B0KZS5|uniprotkb:B0KZU3|uniprotkb:D6W163|ensemblfungi:YNL119W	psi-mi:magac_human(display_long)|uniprotkb:MAGE-12 antigen(gene name synonym)|uniprotkb:MAGE12F antigen(gene name synonym)|uniprotkb:Cancer/testis antigen 1.12(gene name synonym)|uniprotkb:MAGEA12(gene name)|psi-mi:MAGEA12(display_short)|uniprotkb:MAGE12(gene name synonym)	psi-mi:ctu2_yeast(display_long)|uniprotkb:TUC2(gene name synonym)|uniprotkb:N1913(orf name)|uniprotkb:YNL119W(locus name)|uniprotkb:NCS2(gene name)|psi-mi:NCS2(display_short)|uniprotkb:Thiolation of uridine in cytoplasmic tRNA protein 2(gene name synonym)|uniprotkb:CTU2(gene name synonym)|uniprotkb:Needs CLA4 to survive protein 2(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11533849|imex:IM-24995-1204	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001159858.1|refseq:NP_001159859.1|refseq:NP_005358.2|ensembl:ENSG00000213401(gene)|ensembl:ENST00000357916(transcript)|ensembl:ENST00000393869(transcript)|ensembl:ENST00000393900(transcript)|interpro:IPR002190(MAGE protein)|interpro:IPR021072|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|entrezgene/locuslink:4111(identity)	sgd:S000005063|refseq:NP_014280.3|dip:DIP-6649N|mint:P53923|ensemblfungi:YNL119W(gene)|ensemblfungi:YNL119W_mRNA(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0002143"(tRNA wobble position uridine thiolation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0016783"(sulfurtransferase activity)|go:"GO:0032447"(protein urmylation)|go:"GO:0034227"(tRNA thio-modification)|interpro:IPR019407|sgd:YNL119W(identity)	-	-	crc64:420FE465B982C43E	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:3/Jxz2VsFOb67RWqWj3xbTrw3s49606	rogid:TRbLQjCai4jNx+1IaH76vforp8c559292	intact-crc:6973B836678A717E|rigid:FIQmuXNX1WIeQSZFeh016yybyrw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O95273	uniprotkb:P53933	intact:EBI-748961|uniprotkb:A8K3Q0|uniprotkb:A8K3U2|uniprotkb:Q6ZQN9|uniprotkb:Q7Z519|uniprotkb:Q8NBS7|uniprotkb:Q8NBY2|uniprotkb:Q9NS19|uniprotkb:Q9NYH3|uniprotkb:Q9UHX9|ensembl:ENSP00000300213	intact:EBI-28798|uniprotkb:D6W186|ensemblfungi:YNL094W	psi-mi:ccdb1_human(display_long)|uniprotkb:Grap2 and cyclin-D-interacting protein(gene name synonym)|uniprotkb:Human homolog of Maid(gene name synonym)|uniprotkb:CCNDBP1(gene name)|psi-mi:CCNDBP1(display_short)|uniprotkb:DIP1(gene name synonym)|uniprotkb:GCIP(gene name synonym)|uniprotkb:HHM(gene name synonym)	psi-mi:app1_yeast(display_long)|uniprotkb:APP1(gene name)|psi-mi:APP1(display_short)|uniprotkb:Actin patch protein 1(gene name synonym)|uniprotkb:N2219(orf name)|uniprotkb:YNL094W(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11533897|imex:IM-24995-1209	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_036274.3|ensembl:ENSG00000166946(gene)|ensembl:ENST00000300213(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0016604"(nuclear body)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR026907|mint:O95273|rcsb pdb:3AY5|entrezgene/locuslink:23582(identity)	refseq:NP_014305.1|sgd:S000005038|dip:DIP-2006N|mint:P53933|ensemblfungi:YNL094W(gene)|ensemblfungi:YNL094W_mRNA(transcript)|go:"GO:0008195"(phosphatidate phosphatase activity)|go:"GO:0030479"(actin cortical patch)|go:"GO:0044255"(cellular lipid metabolic process)|interpro:IPR017210(Uncharacterised conserved protein UCP037464, actin patch protein 1)|interpro:IPR019236|sgd:YNL094W(identity)	-	-	crc64:B85C525548BA34BC	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Vi9aoFc+Mov6P3X6KGmsTxXqxvM9606	rogid:4ORrWVN2DOL+59LI2qWcKYYVfcE559292	intact-crc:74A7878554D99C48|rigid:iivbEsNNyXz10fs2+QP+UQnmd68	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q08379	uniprotkb:P53933	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	intact:EBI-28798|uniprotkb:D6W186|ensemblfungi:YNL094W	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:app1_yeast(display_long)|uniprotkb:APP1(gene name)|psi-mi:APP1(display_short)|uniprotkb:Actin patch protein 1(gene name synonym)|uniprotkb:N2219(orf name)|uniprotkb:YNL094W(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11533886|imex:IM-24995-1208	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N|entrezgene/locuslink:2801(identity)	refseq:NP_014305.1|sgd:S000005038|dip:DIP-2006N|mint:P53933|ensemblfungi:YNL094W(gene)|ensemblfungi:YNL094W_mRNA(transcript)|go:"GO:0008195"(phosphatidate phosphatase activity)|go:"GO:0030479"(actin cortical patch)|go:"GO:0044255"(cellular lipid metabolic process)|interpro:IPR017210(Uncharacterised conserved protein UCP037464, actin patch protein 1)|interpro:IPR019236|sgd:YNL094W(identity)	-	-	crc64:B85C525548BA34BC	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2017/05/26	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	rogid:4ORrWVN2DOL+59LI2qWcKYYVfcE559292	intact-crc:0CE736CB734F5B25|rigid:aZJHRGm/s29HLT82oyU7qLPpuxw	false	sufficient binding region:383-1002	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9H190	uniprotkb:P53927	intact:EBI-742426|ensembl:ENSP00000371233|uniprotkb:O95892|uniprotkb:Q5W0X1|uniprotkb:Q9BZ42|uniprotkb:Q9H567|uniprotkb:Q9NRY8|intact:EBI-28983470|ensembl:ENSP00000342935|ensembl:ENSP00000354013	intact:EBI-28853|uniprotkb:D6W171|ensemblfungi:YNL110C	psi-mi:sdcb2_human(display_long)|uniprotkb:Similar to TACIP18(gene name synonym)|uniprotkb:SDCBP2(gene name)|psi-mi:SDCBP2(display_short)|uniprotkb:SITAC18(gene name synonym)|uniprotkb:Syndecan-binding protein 2(gene name synonym)	psi-mi:nop15_yeast(display_long)|uniprotkb:YNL110C(locus name)|uniprotkb:N1954(orf name)|uniprotkb:Nucleolar protein 15(gene name synonym)|uniprotkb:NOP15(gene name)|psi-mi:NOP15(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11533858|imex:IM-24995-1205	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001186713.1|refseq:NP_056500.2|refseq:NP_536737.3|ensembl:ENSP00000342935|ensembl:ENSP00000354013|ensembl:ENST00000381808|ensembl:ENSP00000371229|ensembl:ENSP00000371233|ensembl:ENSG00000125775(gene)|ensembl:ENST00000360779(transcript)|ensembl:ENST00000381812(transcript)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007399"(nervous system development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016607"(nuclear speck)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046907"(intracellular transport)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036034|interpro:IPR041489|ensembl:ENST00000339987(transcript)|entrezgene/locuslink:27111(identity)	refseq:NP_014289.1|sgd:S000005054|dip:DIP-4741N|mint:P53927|ensemblfungi:YNL110C(gene)|ensemblfungi:YNL110C_mRNA(transcript)|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0019843"(rRNA binding)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0042273"(ribosomal large subunit biogenesis)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034469|interpro:IPR035979|rcsb pdb:3JCT|rcsb pdb:5T9P|rcsb pdb:5Z3G|rcsb pdb:6C0F|rcsb pdb:6CB1|rcsb pdb:6ELZ|rcsb pdb:6EM1|rcsb pdb:6EM3|rcsb pdb:6EM4|rcsb pdb:6EM5|rcsb pdb:6M62|rcsb pdb:6YLX|rcsb pdb:6YLY|rcsb pdb:7BTB|sgd:YNL110C(identity)	-	-	crc64:EC86E3C77C863292	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:vlEtVZkwLTte5PJ4i8ce+SwE/4Y9606	rogid:WHuY5zx7DUsm1G+00Bc6wM8JAJc559292	intact-crc:2B13786C38499796|rigid:/s3CJWR5qBcco0QZMZrfaau1PRs	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P53930	uniprotkb:Q13155	intact:EBI-28841|uniprotkb:Q6B1N1|uniprotkb:D6W173|ensemblfungi:YNL107W	intact:EBI-745226|uniprotkb:Q75MR1|uniprotkb:Q96CZ5|uniprotkb:Q9P1L2|ensembl:ENSP00000223029|uniprotkb:F8W950	psi-mi:af9_yeast(display_long)|uniprotkb:N1966(orf name)|uniprotkb:YNL107W(locus name)|uniprotkb:YAF9(gene name)|psi-mi:YAF9(display_short)	psi-mi:aimp2_human(display_long)|uniprotkb:Protein JTV-1(gene name synonym)|uniprotkb:AIMP2(gene name)|psi-mi:AIMP2(display_short)|uniprotkb:PRO0992(orf name)|uniprotkb:JTV1(gene name synonym)|uniprotkb:Multisynthase complex auxiliary component p38(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11533867|imex:IM-24995-1206	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005051|refseq:NP_014292.3|dip:DIP-4347N|mint:P53930|ensemblfungi:YNL107W(gene)|ensemblfungi:YNL107W_mRNA(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000812"(Swr1 complex)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006348"|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0043486"(histone exchange)|interpro:IPR005033(YEATS)|interpro:IPR037989|interpro:IPR038704|rcsb pdb:3FK3|rcsb pdb:3RLS|rcsb pdb:6AXJ|reactome:R-SCE-674695|reactome:R-SCE-75955|sgd:YNL107W(identity)	refseq:NP_006294.2|ensembl:ENSG00000106305(gene)|ensembl:ENST00000223029(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0006915"(apoptotic process)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0017101"(aminoacyl-tRNA synthetase multienzyme complex)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060510"(type II pneumocyte differentiation)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1903632"(positive regulation of aminoacyl-tRNA ligase activity)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR031889|interpro:IPR036282|interpro:IPR041503|interpro:IPR042360|mint:Q13155|rcsb pdb:4DPG|rcsb pdb:4YCU|rcsb pdb:4YCW|rcsb pdb:5A1N|rcsb pdb:5A34|rcsb pdb:5A5H|rcsb pdb:5Y6L|rcsb pdb:6ILD|rcsb pdb:6IY6|rcsb pdb:6JPV|rcsb pdb:6K39|reactome:R-HSA-2408522|reactome:R-HSA-379716|dip:DIP-34421N|refseq:NP_001313536.1|entrezgene/locuslink:7965(identity)	-	crc64:1FE08F72942061D1	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:oIwHCTPMu/kBEXUm82Yw5C0YYXw559292	rogid:VEBmJjo6t3dBY6mKpmUyVLamJFQ9606	intact-crc:291236EB7334AD06|rigid:WBnb8LWe6+acKCVJpW2TGVkKTlg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P53930	uniprotkb:Q53HC0	intact:EBI-28841|uniprotkb:Q6B1N1|uniprotkb:D6W173|ensemblfungi:YNL107W	intact:EBI-719994|uniprotkb:Q9H697|uniprotkb:B3KNQ0|ensembl:ENSP00000238156|ensembl:ENSP00000488830	psi-mi:af9_yeast(display_long)|uniprotkb:N1966(orf name)|uniprotkb:YNL107W(locus name)|uniprotkb:YAF9(gene name)|psi-mi:YAF9(display_short)	psi-mi:ccd92_human(display_long)|uniprotkb:Limkain beta-2(gene name synonym)|uniprotkb:CCDC92(gene name)|psi-mi:CCDC92(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11533877|imex:IM-24995-1207	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005051|refseq:NP_014292.3|dip:DIP-4347N|mint:P53930|ensemblfungi:YNL107W(gene)|ensemblfungi:YNL107W_mRNA(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000812"(Swr1 complex)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006348"|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0043486"(histone exchange)|interpro:IPR005033(YEATS)|interpro:IPR037989|interpro:IPR038704|rcsb pdb:3FK3|rcsb pdb:3RLS|rcsb pdb:6AXJ|reactome:R-SCE-674695|reactome:R-SCE-75955|sgd:YNL107W(identity)	refseq:NP_079416.1|ensembl:ENSG00000119242(gene)|ensembl:ENSG00000275035(gene)|ensembl:ENST00000238156(transcript)|ensembl:ENST00000632401(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR033224|interpro:IPR039496|interpro:IPR040370|mint:Q53HC0|refseq:NP_001291886.1|refseq:NP_001291887.1|refseq:NP_001291888.1|refseq:NP_001291889.1|refseq:NP_001291890.1|refseq:XP_005253681.1|refseq:XP_016875473.1|entrezgene/locuslink:80212(identity)	-	crc64:1FE08F72942061D1	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:oIwHCTPMu/kBEXUm82Yw5C0YYXw559292	rogid:Iu/FzTqEpzn8N5WUTt1OwoKWxyc9606	intact-crc:1D4270C7764C8B6D|rigid:So1yakNwnIwuhyz0Ca1SI8vUTvg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P53933	uniprotkb:Q9UNF0	intact:EBI-28798|uniprotkb:D6W186|ensemblfungi:YNL094W	intact:EBI-742503|uniprotkb:O95921|uniprotkb:Q96HV9|uniprotkb:Q9H0D3|uniprotkb:Q9NPN1|uniprotkb:Q9Y4V2|ensembl:ENSP00000385040|ensembl:ENSP00000385372|ensembl:ENSP00000263246	psi-mi:app1_yeast(display_long)|uniprotkb:APP1(gene name)|psi-mi:APP1(display_short)|uniprotkb:Actin patch protein 1(gene name synonym)|uniprotkb:N2219(orf name)|uniprotkb:YNL094W(locus name)	psi-mi:pacn2_human(display_long)|uniprotkb:PACSIN2(gene name)|psi-mi:PACSIN2(display_short)|uniprotkb:Syndapin-II(gene name synonym)|uniprotkb:Syndapin-2(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11533924|imex:IM-24995-1212	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014305.1|sgd:S000005038|dip:DIP-2006N|mint:P53933|ensemblfungi:YNL094W(gene)|ensemblfungi:YNL094W_mRNA(transcript)|go:"GO:0008195"(phosphatidate phosphatase activity)|go:"GO:0030479"(actin cortical patch)|go:"GO:0044255"(cellular lipid metabolic process)|interpro:IPR017210(Uncharacterised conserved protein UCP037464, actin patch protein 1)|interpro:IPR019236|sgd:YNL094W(identity)	refseq:NP_001171899.1|refseq:NP_001171900.1|refseq:NP_009160.2|refseq:XP_005261376.1|refseq:XP_016884053.1|ensembl:ENST00000263246(transcript)|ensembl:ENST00000402229(transcript)|ensembl:ENST00000403744(transcript)|go:"GO:0005215"(transporter activity)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|ensembl:ENSG00000100266(gene)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0032587"(ruffle membrane)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045296"(cadherin binding)|go:"GO:0045806"(negative regulation of endocytosis)|go:"GO:0048858"(cell projection morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070300"(phosphatidic acid binding)|go:"GO:0070836"(caveola assembly)|go:"GO:0072584"(caveolin-mediated endocytosis)|go:"GO:0097320"(plasma membrane tubulation)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR027267|interpro:IPR028521|interpro:IPR031160|interpro:IPR035743|interpro:IPR036028|interpro:IPR037453|mint:Q9UNF0|rcsb pdb:3ABH|rcsb pdb:3ACO|rcsb pdb:3HAJ|rcsb pdb:3Q0K|reactome:R-HSA-8856828|entrezgene/locuslink:11252(identity)	-	crc64:B85C525548BA34BC	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:4ORrWVN2DOL+59LI2qWcKYYVfcE559292	rogid:oEGsyQlsPg61RRGLjBdPGKDmkXc9606	intact-crc:8329439A2AE98E53|rigid:NP6BsaMOKux/N0SroiC1XlUAyrw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P53933	uniprotkb:Q9Y6D9	intact:EBI-28798|uniprotkb:D6W186|ensemblfungi:YNL094W	intact:EBI-742610|uniprotkb:B3KR41|uniprotkb:Q9UNH0|uniprotkb:Q13312|uniprotkb:Q75MI0|uniprotkb:Q86UM4|ensembl:ENSP00000265854|ensembl:ENSP00000382562|ensembl:ENSP00000385334	psi-mi:app1_yeast(display_long)|uniprotkb:APP1(gene name)|psi-mi:APP1(display_short)|uniprotkb:Actin patch protein 1(gene name synonym)|uniprotkb:N2219(orf name)|uniprotkb:YNL094W(locus name)	psi-mi:md1l1_human(display_long)|uniprotkb:Mitotic arrest deficient 1-like protein 1(gene name synonym)|uniprotkb:Mitotic checkpoint MAD1 protein homolog(gene name synonym)|uniprotkb:Tax-binding protein 181(gene name synonym)|uniprotkb:MAD1L1(gene name)|psi-mi:MAD1L1(display_short)|uniprotkb:MAD1(gene name synonym)|uniprotkb:TXBP181(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11533942|imex:IM-24995-1214	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014305.1|sgd:S000005038|dip:DIP-2006N|mint:P53933|ensemblfungi:YNL094W(gene)|ensemblfungi:YNL094W_mRNA(transcript)|go:"GO:0008195"(phosphatidate phosphatase activity)|go:"GO:0030479"(actin cortical patch)|go:"GO:0044255"(cellular lipid metabolic process)|interpro:IPR017210(Uncharacterised conserved protein UCP037464, actin patch protein 1)|interpro:IPR019236|sgd:YNL094W(identity)	refseq:NP_001013858.1|refseq:NP_001013859.1|refseq:NP_003541.2|refseq:NP_001291452.1|refseq:NP_001291453.1|ensembl:ENSG00000002822(gene)|ensembl:ENST00000265854(transcript)|go:"GO:0090235"(regulation of metaphase plate congression)|go:"GO:1902426"(deactivation of mitotic spindle assembly checkpoint)|interpro:IPR008672(Mitotic checkpoint)|mint:Q9Y6D9|rcsb pdb:1GO4|rcsb pdb:4DZO|rcsb pdb:7B1F|rcsb pdb:7B1H|rcsb pdb:7B1J|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|ensembl:ENST00000399654(transcript)|ensembl:ENST00000406869(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043515"(kinetochore binding)|go:"GO:0044615"(nuclear pore nuclear basket)|go:"GO:0048538"(thymus development)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0072686"(mitotic spindle)|refseq:XP_005249934.1|dip:DIP-29654N|entrezgene/locuslink:8379(identity)	-	crc64:B85C525548BA34BC	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:4ORrWVN2DOL+59LI2qWcKYYVfcE559292	rogid:9CcqpZlN0IgqC939rIo7vNgOvLQ9606	intact-crc:0341B6061F2C90FE|rigid:DNKK0rxktXI+kd4CBEvrsnfZ2CA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P53933	uniprotkb:Q9Y5X1	intact:EBI-28798|uniprotkb:D6W186|ensemblfungi:YNL094W	intact:EBI-77848|ensembl:ENSP00000376024|ensembl:ENSP00000506326|uniprotkb:Q9BSI7|uniprotkb:Q9BVM1|uniprotkb:Q9UJH6|uniprotkb:Q9UP20	psi-mi:app1_yeast(display_long)|uniprotkb:APP1(gene name)|psi-mi:APP1(display_short)|uniprotkb:Actin patch protein 1(gene name synonym)|uniprotkb:N2219(orf name)|uniprotkb:YNL094W(locus name)	psi-mi:snx9_human(display_long)|uniprotkb:SNX9(gene name)|psi-mi:SNX9(display_short)|uniprotkb:SH3PX1(gene name synonym)|uniprotkb:SH3PXD3A(gene name synonym)|uniprotkb:SH3 and PX domain-containing protein 1(gene name synonym)|uniprotkb:SH3 and PX domain-containing protein 3A(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11533933|imex:IM-24995-1213	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014305.1|sgd:S000005038|dip:DIP-2006N|mint:P53933|ensemblfungi:YNL094W(gene)|ensemblfungi:YNL094W_mRNA(transcript)|go:"GO:0008195"(phosphatidate phosphatase activity)|go:"GO:0030479"(actin cortical patch)|go:"GO:0044255"(cellular lipid metabolic process)|interpro:IPR017210(Uncharacterised conserved protein UCP037464, actin patch protein 1)|interpro:IPR019236|sgd:YNL094W(identity)	ensembl:ENSG00000130340(gene)|ensembl:ENST00000392185(transcript)|ensembl:ENST00000679814(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0001726"(ruffle)|go:"GO:0005545"(1-phosphatidylinositol binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006897"(endocytosis)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0016197"(endosomal transport)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032437"(cuticular plate)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0036089"(cleavage furrow formation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0051044"(positive regulation of membrane protein ectodomain proteolysis)|go:"GO:0060988"(lipid tube assembly)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071933"(Arp2/3 complex binding)|go:"GO:0097320"(plasma membrane tubulation)|interpro:IPR001452(Src homology-3)|interpro:IPR001683(Phox-like)|interpro:IPR014536(Sorting nexin, Snx9 type)|interpro:IPR019497|interpro:IPR027267|interpro:IPR028644|interpro:IPR035558|interpro:IPR036028|interpro:IPR036871|interpro:IPR037425|interpro:IPR037426|mint:Q9Y5X1|rcsb pdb:2RAI|rcsb pdb:2RAJ|rcsb pdb:2RAK|rcsb pdb:3DYT|rcsb pdb:3DYU|rcsb pdb:3LGE|reactome:R-HSA-432722|reactome:R-HSA-8856828|refseq:NP_057308.1|dip:DIP-30997N|entrezgene/locuslink:51429(identity)	-	crc64:B85C525548BA34BC	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:4ORrWVN2DOL+59LI2qWcKYYVfcE559292	rogid:qtqmMew2psrK6OJPAOWQGTVmNJA9606	intact-crc:C5005044A32624CA|rigid:heE4QMrICB90mjOoLbcWatLpn+8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P53933	uniprotkb:Q15642-2	intact:EBI-28798|uniprotkb:D6W186|ensemblfungi:YNL094W	intact:EBI-6550597|ensembl:ENSP00000320493	psi-mi:app1_yeast(display_long)|uniprotkb:APP1(gene name)|psi-mi:APP1(display_short)|uniprotkb:Actin patch protein 1(gene name synonym)|uniprotkb:N2219(orf name)|uniprotkb:YNL094W(locus name)	psi-mi:q15642-2(display_long)|uniprotkb:A(isoform synonym)|uniprotkb:W(isoform synonym)|uniprotkb:TRIP10(gene name)|psi-mi:TRIP10(display_short)|uniprotkb:CIP4(gene name synonym)|uniprotkb:STOT(gene name synonym)|uniprotkb:STP(gene name synonym)|uniprotkb:Protein Felic(gene name synonym)|uniprotkb:Salt tolerant protein(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 10(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11533915|imex:IM-24995-1211	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014305.1|sgd:S000005038|dip:DIP-2006N|mint:P53933|ensemblfungi:YNL094W(gene)|ensemblfungi:YNL094W_mRNA(transcript)|go:"GO:0008195"(phosphatidate phosphatase activity)|go:"GO:0030479"(actin cortical patch)|go:"GO:0044255"(cellular lipid metabolic process)|interpro:IPR017210(Uncharacterised conserved protein UCP037464, actin patch protein 1)|interpro:IPR019236|sgd:YNL094W(identity)	uniprotkb:Q15642-2(isoform-parent)|ensembl:ENSG00000125733(gene)|ensembl:ENST00000313285(transcript)|intact:EBI-739936(isoform-parent)|entrezgene/locuslink:9322(identity)	-	crc64:B85C525548BA34BC	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:4ORrWVN2DOL+59LI2qWcKYYVfcE559292	rogid:FppLeIANQu5tcNbD11u+F0kSOBQ9606	intact-crc:51D4DD3FC0D2917A|rigid:eMVEToYrW+Tmvt0fj+E8dB1WpiE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P14373	uniprotkb:P53933	intact:EBI-719493|uniprotkb:A2BE15|uniprotkb:Q5RJA8|uniprotkb:Q5ST26|uniprotkb:Q6LA73|uniprotkb:Q6NXR9|uniprotkb:Q9BZY6|uniprotkb:Q9UJL3|ensembl:ENSP00000383555|ensembl:ENSP00000392787|ensembl:ENSP00000405229|ensembl:ENSP00000414793|ensembl:ENSP00000366404	intact:EBI-28798|uniprotkb:D6W186|ensemblfungi:YNL094W	psi-mi:tri27_human(display_long)|uniprotkb:TRIM27(gene name)|psi-mi:TRIM27(display_short)|uniprotkb:RNF76(gene name synonym)|uniprotkb:RFP(gene name synonym)|uniprotkb:Ret finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 27(gene name synonym)|uniprotkb:RING finger protein 76(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM27(gene name synonym)	psi-mi:app1_yeast(display_long)|uniprotkb:APP1(gene name)|psi-mi:APP1(display_short)|uniprotkb:Actin patch protein 1(gene name synonym)|uniprotkb:N2219(orf name)|uniprotkb:YNL094W(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11533906|imex:IM-24995-1210	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006501.1|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0090281"(negative regulation of calcium ion import)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR020457|interpro:IPR035791|interpro:IPR043136|mint:P14373|reactome:R-HSA-3232142|reactome:R-HSA-9635465|reactome:R-HSA-8948751|ensembl:ENSG00000204713(gene)|ensembl:ENSG00000215641(gene)|ensembl:ENSG00000229006(gene)|ensembl:ENSG00000234495(gene)|ensembl:ENSG00000237071(gene)|ensembl:ENST00000377199(transcript)|ensembl:ENST00000400720(transcript)|ensembl:ENST00000431123(transcript)|ensembl:ENST00000435528(transcript)|ensembl:ENST00000437160(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001650"(fibrillar center)|go:"GO:0002820"(negative regulation of adaptive immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|entrezgene/locuslink:5987(identity)	refseq:NP_014305.1|sgd:S000005038|dip:DIP-2006N|mint:P53933|ensemblfungi:YNL094W(gene)|ensemblfungi:YNL094W_mRNA(transcript)|go:"GO:0008195"(phosphatidate phosphatase activity)|go:"GO:0030479"(actin cortical patch)|go:"GO:0044255"(cellular lipid metabolic process)|interpro:IPR017210(Uncharacterised conserved protein UCP037464, actin patch protein 1)|interpro:IPR019236|sgd:YNL094W(identity)	-	-	crc64:B85C525548BA34BC	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:dsfH5OUghD8KSaTz1SFw9OYVTK49606	rogid:4ORrWVN2DOL+59LI2qWcKYYVfcE559292	intact-crc:BA9B99923375587F|rigid:p9Jc60yOsm+pNpOb2wwtG/yIjMQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q969F0	uniprotkb:P54074	intact:EBI-743099|ensembl:ENSP00000359375	intact:EBI-27241|uniprotkb:D6VZU2|ensemblfungi:YMR119W	psi-mi:fate1_human(display_long)|uniprotkb:Tumor antigen BJ-HCC-2(gene name synonym)|uniprotkb:Cancer/testis antigen 43(gene name synonym)|uniprotkb:FATE1(gene name)|psi-mi:FATE1(display_short)|uniprotkb:FATE(gene name synonym)	psi-mi:asi1_yeast(display_long)|uniprotkb:YMR119W(locus name)|uniprotkb:YM9718.18(orf name)|uniprotkb:YM8564.01(orf name)|uniprotkb:Amino acid sensor-independent protein 1(gene name synonym)|uniprotkb:ASI1(gene name)|psi-mi:ASI1(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11533969|imex:IM-24995-1217	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_149076.1|ensembl:ENSG00000147378(gene)|ensembl:ENST00000370350(transcript)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|go:"GO:0051562"(negative regulation of mitochondrial calcium ion concentration)|interpro:IPR039153|interpro:IPR039433|mint:Q969F0|entrezgene/locuslink:89885(identity)	refseq:NP_013837.1|sgd:S000004725|dip:DIP-7733N|ensemblfungi:YMR119W(gene)|ensemblfungi:YMR119W_mRNA(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034399"(nuclear periphery)|go:"GO:0036369"(transcription factor catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0097658"(Asi complex)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|sgd:YMR119W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Nm1N6lO92MHr5rIKC007oouF5RE9606	rogid:CvH0AkCWby1t6LwuYC0K/dI2jgo559292	intact-crc:213F8B7097C30AFE|rigid:9yTvzpIj8pynG9tcp0PMLW1HC3U	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P54784	uniprotkb:Q96EY1-3	intact:EBI-12568|uniprotkb:D6VZA8|ensemblfungi:YML065W	intact:EBI-11526226|ensembl:ENSP00000393970	psi-mi:orc1_yeast(display_long)|uniprotkb:ORC1(gene name)|psi-mi:ORC1(display_short)|uniprotkb:YML065W(locus name)|uniprotkb:Origin recognition complex 120 kDa subunit(gene name synonym)	psi-mi:q96ey1-3(display_long)|uniprotkb:DnaJ protein Tid-1(gene name synonym)|uniprotkb:HCA57(gene name synonym)|uniprotkb:Hepatocellular carcinoma-associated antigen 57(gene name synonym)|uniprotkb:TID1(gene name synonym)|uniprotkb:Tumorous imaginal discs protein Tid56 homolog(gene name synonym)|uniprotkb:DNAJA3(gene name)|psi-mi:DNAJA3(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11533978|imex:IM-24995-1218	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:6WGG|rcsb pdb:6WGI|rcsb pdb:7MCA|reactome:R-SCE-68616|rcsb pdb:6WGC|reactome:R-SCE-68949|reactome:R-SCE-68962|ensemblfungi:YML065W(gene)|ensemblfungi:YML065W_mRNA(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031491"(nucleosome binding)|go:"GO:0033314"(mitotic DNA replication checkpoint signaling)|go:"GO:0043007"(maintenance of rDNA)|go:"GO:0046872"(metal ion binding)|interpro:IPR001025(Bromo adjacent region)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR020793|interpro:IPR027417|interpro:IPR041083|interpro:IPR043151|rcsb pdb:1M4Z|rcsb pdb:1ZBX|rcsb pdb:1ZHI|rcsb pdb:5V8F|rcsb pdb:5ZR1|rcsb pdb:6OM3|rcsb pdb:6RQC|refseq:NP_013646.1|sgd:S000004530|dip:DIP-2284N|mint:P54784|sgd:YML065W(identity)	intact:EBI-356767(isoform-parent)|ensembl:ENSG00000103423(gene)|ensembl:ENST00000431375(transcript)|uniprotkb:Q96EY1-3(isoform-parent)|entrezgene/locuslink:9093(identity)	-	crc64:BDAA9D3E40B4B76A	isoform-comment:"Ref.3 (BAG58345) sequence is in conflict in position: 33:Y->H."	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:ZTOvWqU+Rxwll7cRwOUsRqJC08M559292	rogid:nMH4IaOZYO5w5bh+cdX4LoPSisc9606	intact-crc:716749D3BF5ECDBC|rigid:uyQdY0emWwd3M6pHBgtdiMY4lq0	false	-	sufficient binding region:60-300	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P54787	uniprotkb:O14641	intact:EBI-20495|uniprotkb:D6W0I8|ensemblfungi:YML097C	intact:EBI-740850|ensembl:ENSP00000005340|uniprotkb:Q53XM0|uniprotkb:D3DTN3	psi-mi:vps9_yeast(display_long)|uniprotkb:VPS9(gene name)|psi-mi:VPS9(display_short)|uniprotkb:Vacuolar protein-targeting protein 9(gene name synonym)|uniprotkb:VPT9(gene name synonym)|uniprotkb:YML097C(locus name)	psi-mi:dvl2_human(display_long)|uniprotkb:DSH homolog 2(gene name synonym)|uniprotkb:DVL2(gene name)|psi-mi:DVL2(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11533989|imex:IM-24995-1219	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013612.1|sgd:S000004563|ensemblfungi:YML097C(gene)|ensemblfungi:YML097C_mRNA(transcript)|go:"GO:0000011"(vacuole inheritance)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR009060(UBA-like)|interpro:IPR037191|interpro:IPR041545|interpro:IPR041804|rcsb pdb:1MN3|rcsb pdb:1P3Q|reactome:R-SCE-8876198|reactome:R-SCE-8856828|dip:DIP-4526N|mint:P54787|sgd:YML097C(identity)	refseq:NP_004413.1|ensembl:ENSG00000004975(gene)|ensembl:ENST00000005340(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005109"(frizzled binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0007507"(heart development)|go:"GO:0016235"(aggresome)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044340"(canonical Wnt signaling pathway involved in regulation of cell proliferation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0150012"(positive regulation of neuron projection arborization)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008341(Dishevelled-2 region)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:O14641|rcsb pdb:2REY|rcsb pdb:3CBX|rcsb pdb:3CBY|rcsb pdb:3CBZ|rcsb pdb:3CC0|rcsb pdb:4WIP|rcsb pdb:5LNP|rcsb pdb:5SUY|rcsb pdb:5SUZ|rcsb pdb:6IW3|rcsb pdb:6JCK|reactome:R-HSA-201681|reactome:R-HSA-201688|reactome:R-HSA-2028269|reactome:R-HSA-4086400|reactome:R-HSA-4608870|reactome:R-HSA-4641258|reactome:R-HSA-4641262|reactome:R-HSA-5099900|reactome:R-HSA-5368598|reactome:R-HSA-5663220|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9673324|ensembl:ENSP00000005340|dip:DIP-34433N|entrezgene/locuslink:1856(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:ogXRiOOp698mlPdAiFidYakMtI4559292	rogid:2Vdc8oRnT4Mz/j+EXQXrL3AszOc9606	intact-crc:EC6A1CC9ECD008BF|rigid:6vhH6nB5Hy1JS8ihA9K04mjJlK4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96CN4	uniprotkb:P53949	intact:EBI-749523|uniprotkb:B9A6I9|ensembl:ENSP00000270530	intact:EBI-28725|uniprotkb:Q6B2U7|uniprotkb:D6W1C2|ensemblfungi:YNL056W	psi-mi:evi5l_human(display_long)|uniprotkb:Ecotropic viral integration site 5-like protein(gene name synonym)|uniprotkb:EVI5L(gene name)|psi-mi:EVI5L(display_short)	psi-mi:oca2_yeast(display_long)|uniprotkb:YNL056W(locus name)|uniprotkb:N2439(orf name)|uniprotkb:YNL2439W(orf name)|uniprotkb:Oxidant-induced cell-cycle arrest protein 2(gene name synonym)|uniprotkb:OCA2(gene name)|psi-mi:OCA2(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11533951|imex:IM-24995-1215	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153416.1|refseq:NP_660288.1|refseq:XP_005272515.1|refseq:XP_016881728.1|ensembl:ENSG00000142459(gene)|ensembl:ENST00000270530(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0031267"(small GTPase binding)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:1902018"(negative regulation of cilium assembly)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR031214|interpro:IPR035969|entrezgene/locuslink:115704(identity)	sgd:S000005001|refseq:NP_014342.3|dip:DIP-1989N|mint:P53949|ensemblfungi:YNL056W(gene)|ensemblfungi:YNL056W_mRNA(transcript)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005737"(cytoplasm)|interpro:IPR004861(Protein-tyrosine phosphatase, SIW14-like)|interpro:IPR020422|interpro:IPR029021|sgd:YNL056W(identity)	-	-	crc64:B5CF05FAABD9C236	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:OKfnOqdRupGBmq6gqoeApO0cgG09606	rogid:Ydjdu1aqlhPFCckVB/BjaRa1ITI559292	intact-crc:FFBD0F4C81DB3748|rigid:FiiWoxOKb2DhlfBnfPd0ypQsGbc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P53953	uniprotkb:Q53G59	intact:EBI-17006|uniprotkb:D6W1D0|ensemblfungi:YNL049C	intact:EBI-740929|ensembl:ENSP00000356230|uniprotkb:A6NEN8|uniprotkb:B7Z7B8|uniprotkb:Q9HBX5	psi-mi:sfb2_yeast(display_long)|uniprotkb:SFB2(gene name)|psi-mi:SFB2(display_short)|uniprotkb:ISS1(gene name synonym)|uniprotkb:YNL049C(locus name)|uniprotkb:N2505(orf name)|uniprotkb:YNL2505C(orf name)|uniprotkb:SEC24-related protein 2(gene name synonym)	psi-mi:klh12_human(display_long)|uniprotkb:CUL3-interacting protein 1(gene name synonym)|uniprotkb:KLHL12(gene name)|psi-mi:KLHL12(display_short)|uniprotkb:C3IP1(gene name synonym)|uniprotkb:DKIR homolog(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11533960|imex:IM-24995-1216	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YNL049C(gene)|ensemblfungi:YNL049C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0005048"(signal sequence binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:0090110"(COPII-coated vesicle cargo loading)|interpro:IPR006896(Sec23/Sec24 trunk region)|interpro:IPR006900(Sec23/Sec24 helical region)|interpro:IPR007123(Gelsolin region)|interpro:IPR012990(Sec23/Sec24 beta-sandwich)|interpro:IPR029006|interpro:IPR036174|interpro:IPR036175|interpro:IPR036180|interpro:IPR036465|interpro:IPR041742|reactome:R-SCE-204005|reactome:R-SCE-5694530|reactome:R-SCE-983170|interpro:IPR006895(Zinc finger, Sec23/Sec24-type)|refseq:NP_014349.1|sgd:S000004994|dip:DIP-4370N|mint:P53953|sgd:YNL049C(identity)	go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048208"(COPII vesicle coating)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR017096(Kelch-like protein, gigaxonin)|mint:Q53G59|rcsb pdb:2VPJ|rcsb pdb:6TTK|rcsb pdb:6V7O|reactome:R-HSA-4641258|refseq:NP_067646.1|ensembl:ENSG00000117153(gene)|ensembl:ENST00000367261(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0014029"(neural crest formation)|go:"GO:0014032"(neural crest cell development)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0034451"(centriolar satellite)|refseq:NP_001289980.1|refseq:NP_001290038.1|entrezgene/locuslink:59349(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:rG9Y9x8CduERmQuwFxUU/Z/wD1A559292	rogid:C4I/Ys9vqNqfG61HsXRZhywP4vE9606	intact-crc:E0EB76E1B4D9F86E|rigid:f+ZAsu7g439pPlhuwB+oe75JgIs	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UMX0	uniprotkb:P54860	intact:EBI-741480|uniprotkb:Q8IXS9|uniprotkb:Q8N2Q3|uniprotkb:Q9H0T8|uniprotkb:Q9H3R4|uniprotkb:Q9HAZ5|intact:EBI-28967608|ensembl:ENSP00000365576|uniprotkb:Q5T6J5|uniprotkb:Q5T6J9|uniprotkb:A0A024R284	intact:EBI-20003|uniprotkb:D6VRG3|ensemblfungi:YDL190C	psi-mi:ubql1_human(display_long)|uniprotkb:Protein linking IAP with cytoskeleton 1(gene name synonym)|uniprotkb:UBQLN1(gene name)|psi-mi:UBQLN1(display_short)|uniprotkb:DA41(gene name synonym)|uniprotkb:PLIC1(gene name synonym)	psi-mi:ufd2_yeast(display_long)|uniprotkb:UFD2(gene name)|psi-mi:UFD2(display_short)|uniprotkb:YDL190C(locus name)|uniprotkb:D1255(orf name)|uniprotkb:Ubiquitin fusion degradation protein 2(gene name synonym)|uniprotkb:Ubiquitin conjugation factor E4(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase UFD2(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11534018|imex:IM-24995-1222	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000257468|ensembl:ENSP00000257468|ensembl:ENSP00000365576|ensembl:ENSG00000135018(gene)|ensembl:ENST00000376395(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000502"(proteasome complex)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016235"(aggresome)|go:"GO:0016236"(macroautophagy)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0019900"(kinase binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035973"(aggrephagy)|go:"GO:0042802"(identical protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0097352"(autophagosome maturation)|go:"GO:1901340"(negative regulation of store-operated calcium channel activity)|go:"GO:1902175"(regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)|interpro:IPR000626(Ubiquitin)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR028430|interpro:IPR029071|mint:Q9UMX0|rcsb pdb:2JY5|rcsb pdb:2JY6|rcsb pdb:2KLC|reactome:R-HSA-8856825|refseq:NP_038466.2|refseq:NP_444295.1|dip:DIP-41629N|entrezgene/locuslink:29979(identity)	refseq:NP_010091.2|sgd:S000002349|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR003613(U box)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|go:"GO:0016567"(protein ubiquitination)|interpro:IPR019474|rcsb pdb:2QIZ|rcsb pdb:2QJ0|rcsb pdb:3M62|rcsb pdb:3M63|reactome:R-SCE-983168|ensemblfungi:YDL190C(gene)|ensemblfungi:YDL190C_mRNA(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|dip:DIP-5925N|mint:P54860|sgd:YDL190C(identity)	-	-	crc64:877ACB59AC29634A	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:nCFfZbGCTvRYaXhQ4R99XblslvM9606	rogid:E8YkPPAM7RTsLwjUHSHNCjQWq9M559292	intact-crc:B97E440F7E0A4893|rigid:4IfUBzrlDlTBoaaa1l8LS7SojVE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P54791	uniprotkb:Q08379	intact:EBI-12580|uniprotkb:D6W4G3|ensemblfungi:YPR162C	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	psi-mi:orc4_yeast(display_long)|uniprotkb:ORC4(gene name)|psi-mi:ORC4(display_short)|uniprotkb:YPR162C(locus name)|uniprotkb:P9325.5(orf name)|uniprotkb:Origin recognition complex 56 kDa subunit(gene name synonym)	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11534007|imex:IM-24995-1221	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YPR162C(gene)|ensemblfungi:YPR162C_mRNA(transcript)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031261"(DNA replication preinitiation complex)|interpro:IPR016527(Origin recognition complex, subunit 4)|interpro:IPR027417|interpro:IPR032705|rcsb pdb:5V8F|rcsb pdb:5ZR1|rcsb pdb:6RQC|rcsb pdb:6WGC|rcsb pdb:6WGG|rcsb pdb:6WGI|rcsb pdb:7MCA|reactome:R-SCE-68616|reactome:R-SCE-68962|reactome:R-SCE-68949|refseq:NP_015488.1|sgd:S000006366|dip:DIP-2287N|mint:P54791|sgd:YPR162C(identity)	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N|entrezgene/locuslink:2801(identity)	-	crc64:ACF064F2C633F13F	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2017/05/26	rogid:kJZ5UJVsvZNFQEkBR9tmPOJ+Iv8559292	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	intact-crc:48DA0CE8E7FEBD96|rigid:DSx17Ve2DO16uWh9vlHWt53cQjM	false	-	sufficient binding region:383-1002	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P54787	uniprotkb:Q15038	intact:EBI-20495|uniprotkb:D6W0I8|ensemblfungi:YML097C	intact:EBI-724310|ensembl:ENSP00000394699|uniprotkb:E9PB45|uniprotkb:A8K254|uniprotkb:B4DDT5|uniprotkb:C9JA96|uniprotkb:C9JP84|uniprotkb:B4E1G3|uniprotkb:F8VU62	psi-mi:vps9_yeast(display_long)|uniprotkb:VPS9(gene name)|psi-mi:VPS9(display_short)|uniprotkb:Vacuolar protein-targeting protein 9(gene name synonym)|uniprotkb:VPT9(gene name synonym)|uniprotkb:YML097C(locus name)	psi-mi:dazp2_human(display_long)|uniprotkb:Deleted in azoospermia-associated protein 2(gene name synonym)|uniprotkb:DAZAP2(gene name)|psi-mi:DAZAP2(display_short)|uniprotkb:KIAA0058(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11533998|imex:IM-24995-1220	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013612.1|sgd:S000004563|ensemblfungi:YML097C(gene)|ensemblfungi:YML097C_mRNA(transcript)|go:"GO:0000011"(vacuole inheritance)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR009060(UBA-like)|interpro:IPR037191|interpro:IPR041545|interpro:IPR041804|rcsb pdb:1MN3|rcsb pdb:1P3Q|reactome:R-SCE-8876198|reactome:R-SCE-8856828|dip:DIP-4526N|mint:P54787|sgd:YML097C(identity)	ensembl:ENSG00000183283(gene)|ensembl:ENST00000412716(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0016607"(nuclear speck)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0050699"(WW domain binding)|interpro:IPR022730|mint:Q15038|refseq:NP_001129736.1|refseq:NP_055579.1|ensembl:ENSP00000394699|ensembl:ENST00000425012|ensembl:ENSP00000408251|ensembl:ENST00000439799|ensembl:ENSP00000398804|ensembl:ENST00000449723|ensembl:ENSP00000412812|ensembl:ENST00000549555|ensembl:ENSP00000448051|ensembl:ENST00000549732|ensembl:ENSP00000446554|refseq:NP_001129741.1|refseq:NP_001129739.1|refseq:NP_001129740.1|refseq:NP_001129738.1|entrezgene/locuslink:9802(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:ogXRiOOp698mlPdAiFidYakMtI4559292	rogid:ASRqCZBG4q1U/y95PUSMKsgfm/g9606	intact-crc:8C6AD3AFD9945175|rigid:DwpVDWgt7l//tipQ+xSc9Jye/M8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P63279	uniprotkb:P60010	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	intact:EBI-2169|uniprotkb:P02579|uniprotkb:Q9P3X6|uniprotkb:Q9P3X7|uniprotkb:D6VTJ1|ensemblfungi:YFL039C	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:act_yeast(display_long)|uniprotkb:ACT1(gene name)|psi-mi:ACT1(display_short)|uniprotkb:ABY1(gene name synonym)|uniprotkb:END7(gene name synonym)|uniprotkb:YFL039C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11534056|imex:IM-24995-1226	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N|entrezgene/locuslink:7329(identity)	refseq:NP_116614.1|sgd:S000001855|dip:DIP-310N|mint:P60010|ensemblfungi:YFL039C(gene)|ensemblfungi:YFL039C_mRNA(transcript)|go:"GO:0000011"(vacuole inheritance)|go:"GO:0000142"(cellular bud neck contractile ring)|go:"GO:0000812"(Swr1 complex)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005524"(ATP binding)|go:"GO:0005884"(actin filament)|go:"GO:0006281"(DNA repair)|go:"GO:0006897"(endocytosis)|go:"GO:0009306"(protein secretion)|go:"GO:0016573"(histone acetylation)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030476"(ascospore wall assembly)|go:"GO:0030479"(actin cortical patch)|go:"GO:0031011"(Ino80 complex)|go:"GO:0032432"(actin filament bundle)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:1902404"(mitotic actomyosin contractile ring contraction)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|rcsb pdb:1YAG|rcsb pdb:1YVN|rcsb pdb:5NBL|rcsb pdb:5NBM|rcsb pdb:5NBN|rcsb pdb:5Y81|reactome:R-SCE-114608|reactome:R-SCE-190873|reactome:R-SCE-196025|reactome:R-SCE-2029482|reactome:R-SCE-5626467|reactome:R-SCE-5663213|reactome:R-SCE-8856828|reactome:R-SCE-8980692|reactome:R-SCE-9013026|sgd:YFL039C(identity)	-	-	crc64:87AC19B0B0BC9E71	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	rogid:yfgwiWq/Y0HviACqgjjUugpEKLw559292	intact-crc:EBF013B513715026|rigid:19emcZCbYXAS9jiEmSlPqcW4P9M	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P60010	uniprotkb:P63261	intact:EBI-2169|uniprotkb:P02579|uniprotkb:Q9P3X6|uniprotkb:Q9P3X7|uniprotkb:D6VTJ1|ensemblfungi:YFL039C	intact:EBI-351292|uniprotkb:P02571|uniprotkb:P14104|uniprotkb:P99022|uniprotkb:Q5U032|uniprotkb:Q96E67|uniprotkb:A8K7C2|ensembl:ENSP00000505060|ensembl:ENSP00000505193|ensembl:ENSP00000505235|ensembl:ENSP00000506126|ensembl:ENSP00000506201|ensembl:ENSP00000506253|ensembl:ENSP00000458162|ensembl:ENSP00000458435|ensembl:ENSP00000459119|ensembl:ENSP00000459124|ensembl:ENSP00000460464|ensembl:ENSP00000460660|ensembl:ENSP00000461672|ensembl:ENSP00000466346|ensembl:ENSP00000477968	psi-mi:act_yeast(display_long)|uniprotkb:ACT1(gene name)|psi-mi:ACT1(display_short)|uniprotkb:ABY1(gene name synonym)|uniprotkb:END7(gene name synonym)|uniprotkb:YFL039C(locus name)	psi-mi:actg_human(display_long)|uniprotkb:ACTG1(gene name)|psi-mi:ACTG1(display_short)|uniprotkb:ACTG(gene name synonym)|uniprotkb:Gamma-actin(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11534046|imex:IM-24995-1225	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_116614.1|sgd:S000001855|dip:DIP-310N|mint:P60010|ensemblfungi:YFL039C(gene)|ensemblfungi:YFL039C_mRNA(transcript)|go:"GO:0000011"(vacuole inheritance)|go:"GO:0000142"(cellular bud neck contractile ring)|go:"GO:0000812"(Swr1 complex)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005524"(ATP binding)|go:"GO:0005884"(actin filament)|go:"GO:0006281"(DNA repair)|go:"GO:0006897"(endocytosis)|go:"GO:0009306"(protein secretion)|go:"GO:0016573"(histone acetylation)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030476"(ascospore wall assembly)|go:"GO:0030479"(actin cortical patch)|go:"GO:0031011"(Ino80 complex)|go:"GO:0032432"(actin filament bundle)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:1902404"(mitotic actomyosin contractile ring contraction)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|rcsb pdb:1YAG|rcsb pdb:1YVN|rcsb pdb:5NBL|rcsb pdb:5NBM|rcsb pdb:5NBN|rcsb pdb:5Y81|reactome:R-SCE-114608|reactome:R-SCE-190873|reactome:R-SCE-196025|reactome:R-SCE-2029482|reactome:R-SCE-5626467|reactome:R-SCE-5663213|reactome:R-SCE-8856828|reactome:R-SCE-8980692|reactome:R-SCE-9013026|sgd:YFL039C(identity)	refseq:NP_001186883.1|refseq:NP_001605.1|ensembl:ENST00000570382(transcript)|ensembl:ENSG00000184009(gene)|ensembl:ENST00000571721(transcript)|ensembl:ENST00000573283(transcript)|ensembl:ENST00000575087(transcript)|ensembl:ENST00000575659(transcript)|ensembl:ENST00000575842(transcript)|ensembl:ENST00000575994(transcript)|ensembl:ENST00000576544(transcript)|ensembl:ENST00000615544(transcript)|ensembl:ENST00000679480(transcript)|ensembl:ENST00000679778(transcript)|ensembl:ENST00000680227(transcript)|ensembl:ENST00000680727(transcript)|ensembl:ENST00000681052(transcript)|ensembl:ENST00000681842(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0001895"(retina homeostasis)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005522"(profilin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0030016"(myofibril)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031941"(filamentous actin)|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0044305"(calyx of Held)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0051492"(regulation of stress fiber assembly)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070527"(platelet aggregation)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0072562"(blood microparticle)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0097433"(dense body)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098973"(structural constituent of postsynaptic actin cytoskeleton)|go:"GO:0120192"(tight junction assembly)|go:"GO:0120220"(basal body patch)|go:"GO:0150111"(regulation of transepithelial transport)|go:"GO:1902396"(protein localization to bicellular tight junction)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P63261|rcsb pdb:5JLH|rcsb pdb:6CXI|rcsb pdb:6CXJ|rcsb pdb:6G2T|rcsb pdb:6V62|rcsb pdb:6V63|rcsb pdb:6WK1|rcsb pdb:6WK2|reactome:R-HSA-1445148|reactome:R-HSA-190873|reactome:R-HSA-196025|reactome:R-HSA-2029482|reactome:R-HSA-3928662|reactome:R-HSA-3928665|reactome:R-HSA-418990|reactome:R-HSA-437239|reactome:R-HSA-4420097|reactome:R-HSA-445095|reactome:R-HSA-446353|reactome:R-HSA-5626467|reactome:R-HSA-5663213|reactome:R-HSA-5663220|reactome:R-HSA-5674135|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8856828|reactome:R-HSA-9013418|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9662360|reactome:R-HSA-9662361|reactome:R-HSA-9664422|entrezgene/locuslink:71(identity)	-	crc64:87AC19B0B0BC9E71	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:yfgwiWq/Y0HviACqgjjUugpEKLw559292	rogid:B2OOsE06lTfo90H3g8tlmUJQ7cY9606	intact-crc:D8F11288449E5CAC|rigid:RZtrroqUOrg1ChAbVxQhz5fMr1w	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P60709	uniprotkb:P60010	intact:EBI-353944|uniprotkb:P02570|uniprotkb:P70514|uniprotkb:P99021|uniprotkb:Q11211|uniprotkb:Q64316|uniprotkb:Q75MN2|uniprotkb:Q96B34|uniprotkb:Q96HG5|ensembl:ENSP00000494269|ensembl:ENSP00000494750|ensembl:ENSP00000495995|ensembl:ENSP00000501862|ensembl:ENSP00000502821	intact:EBI-2169|uniprotkb:P02579|uniprotkb:Q9P3X6|uniprotkb:Q9P3X7|uniprotkb:D6VTJ1|ensemblfungi:YFL039C	psi-mi:actb_human(display_long)|uniprotkb:ACTB(gene name)|psi-mi:ACTB(display_short)|uniprotkb:Beta-actin(gene name synonym)	psi-mi:act_yeast(display_long)|uniprotkb:ACT1(gene name)|psi-mi:ACT1(display_short)|uniprotkb:ABY1(gene name synonym)|uniprotkb:END7(gene name synonym)|uniprotkb:YFL039C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11534036|imex:IM-24995-1224	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001092.1|ensembl:ENSG00000075624(gene)|ensembl:ENST00000493945(transcript)|ensembl:ENST00000642480(transcript)|ensembl:ENST00000646664(transcript)|ensembl:ENST00000674681(transcript)|ensembl:ENST00000675515(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000785"(chromatin)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0001895"(retina homeostasis)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007409"(axonogenesis)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019894"(kinesin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0022898"(regulation of transmembrane transporter activity)|go:"GO:0030027"(lamellipodium)|go:"GO:0030424"(axon)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0030957"(Tat protein binding)|go:"GO:0031982"(vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034333"(adherens junction assembly)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043044"|go:"GO:0043296"(apical junction complex)|go:"GO:0044305"(calyx of Held)|go:"GO:0045176"(apical protein localization)|go:"GO:0045202"(synapse)|go:"GO:0048156"(tau protein binding)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048870"(cell motility)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051621"(regulation of norepinephrine uptake)|go:"GO:0051623"(positive regulation of norepinephrine uptake)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070160"(tight junction)|go:"GO:0070527"(platelet aggregation)|reactome:R-HSA-4420097|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0072562"(blood microparticle)|go:"GO:0072749"(cellular response to cytochalasin B)|go:"GO:0097433"(dense body)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098973"(structural constituent of postsynaptic actin cytoskeleton)|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0150111"(regulation of transepithelial transport)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P60709|rcsb pdb:3BYH|rcsb pdb:3D2U|rcsb pdb:3J82|rcsb pdb:3LUE|rcsb pdb:6ANU|rcsb pdb:6ICT|rcsb pdb:6ICV|rcsb pdb:6LTJ|rcsb pdb:6MBJ|rcsb pdb:6MBK|rcsb pdb:6MBL|rcsb pdb:6NBW|rcsb pdb:6OX0|rcsb pdb:6OX1|rcsb pdb:6OX2|rcsb pdb:6OX3|rcsb pdb:6OX4|rcsb pdb:6OX5|rcsb pdb:6V62|rcsb pdb:6V63|rcsb pdb:6WK1|rcsb pdb:6WK2|rcsb pdb:7AS4|reactome:R-HSA-1445148|reactome:R-HSA-190873|reactome:R-HSA-196025|reactome:R-HSA-2029482|reactome:R-HSA-3214847|reactome:R-HSA-389957|reactome:R-HSA-390450|reactome:R-HSA-3928662|reactome:R-HSA-3928665|reactome:R-HSA-418990|reactome:R-HSA-437239|reactome:R-HSA-446353|reactome:R-HSA-5250924|reactome:R-HSA-5626467|reactome:R-HSA-5663213|reactome:R-HSA-5663220|reactome:R-HSA-5674135|reactome:R-HSA-5689603|reactome:R-HSA-5696394|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8856828|reactome:R-HSA-9035034|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9662360|reactome:R-HSA-9662361|reactome:R-HSA-9664422|reactome:R-HSA-983231|reactome:R-HSA-445095|dip:DIP-29686N|entrezgene/locuslink:60(identity)	refseq:NP_116614.1|sgd:S000001855|dip:DIP-310N|mint:P60010|ensemblfungi:YFL039C(gene)|ensemblfungi:YFL039C_mRNA(transcript)|go:"GO:0000011"(vacuole inheritance)|go:"GO:0000142"(cellular bud neck contractile ring)|go:"GO:0000812"(Swr1 complex)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005524"(ATP binding)|go:"GO:0005884"(actin filament)|go:"GO:0006281"(DNA repair)|go:"GO:0006897"(endocytosis)|go:"GO:0009306"(protein secretion)|go:"GO:0016573"(histone acetylation)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030476"(ascospore wall assembly)|go:"GO:0030479"(actin cortical patch)|go:"GO:0031011"(Ino80 complex)|go:"GO:0032432"(actin filament bundle)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:1902404"(mitotic actomyosin contractile ring contraction)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|rcsb pdb:1YAG|rcsb pdb:1YVN|rcsb pdb:5NBL|rcsb pdb:5NBM|rcsb pdb:5NBN|rcsb pdb:5Y81|reactome:R-SCE-114608|reactome:R-SCE-190873|reactome:R-SCE-196025|reactome:R-SCE-2029482|reactome:R-SCE-5626467|reactome:R-SCE-5663213|reactome:R-SCE-8856828|reactome:R-SCE-8980692|reactome:R-SCE-9013026|sgd:YFL039C(identity)	-	-	crc64:87AC19B0B0BC9E71	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Hoge1B8Pn56kvbNTpkSLsQuHwRc9606	rogid:yfgwiWq/Y0HviACqgjjUugpEKLw559292	intact-crc:19B0D9234061C479|rigid:YgERg3OzIJM/7XW/p2uhHxVz360	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40123	uniprotkb:P60010	intact:EBI-1051165|uniprotkb:Q6IAY2|uniprotkb:B2R5Y3|intact:EBI-11045298|uniprotkb:B7Z1C4|uniprotkb:B7Z214|ensembl:ENSP00000229922	intact:EBI-2169|uniprotkb:P02579|uniprotkb:Q9P3X6|uniprotkb:Q9P3X7|uniprotkb:D6VTJ1|ensemblfungi:YFL039C	psi-mi:cap2_human(display_long)|uniprotkb:CAP2(gene name)|psi-mi:CAP2(display_short)	psi-mi:act_yeast(display_long)|uniprotkb:ACT1(gene name)|psi-mi:ACT1(display_short)|uniprotkb:ABY1(gene name synonym)|uniprotkb:END7(gene name synonym)|uniprotkb:YFL039C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11534027|imex:IM-24995-1223	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006357.1|ensembl:ENSG00000112186(gene)|ensembl:ENST00000229922(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007165"(signal transduction)|go:"GO:0007190"(activation of adenylate cyclase activity)|go:"GO:0008179"(adenylate cyclase binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0042802"(identical protein binding)|go:"GO:0045761"(regulation of adenylate cyclase activity)|interpro:IPR001837(Adenylate cyclase-associated CAP)|interpro:IPR006599(CARP motif)|interpro:IPR013912(Adenylate cyclase-associated CAP,  C-terminal)|interpro:IPR013992(Adenylate cyclase-associated CAP, N-terminal)|interpro:IPR016098(Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal)|interpro:IPR017901|interpro:IPR018106|interpro:IPR028417|interpro:IPR028418|interpro:IPR036222|interpro:IPR036223|reactome:R-HSA-428890|go:"GO:0005886"(plasma membrane)|entrezgene/locuslink:10486(identity)	refseq:NP_116614.1|sgd:S000001855|dip:DIP-310N|mint:P60010|ensemblfungi:YFL039C(gene)|ensemblfungi:YFL039C_mRNA(transcript)|go:"GO:0000011"(vacuole inheritance)|go:"GO:0000142"(cellular bud neck contractile ring)|go:"GO:0000812"(Swr1 complex)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005524"(ATP binding)|go:"GO:0005884"(actin filament)|go:"GO:0006281"(DNA repair)|go:"GO:0006897"(endocytosis)|go:"GO:0009306"(protein secretion)|go:"GO:0016573"(histone acetylation)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030476"(ascospore wall assembly)|go:"GO:0030479"(actin cortical patch)|go:"GO:0031011"(Ino80 complex)|go:"GO:0032432"(actin filament bundle)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:1902404"(mitotic actomyosin contractile ring contraction)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|rcsb pdb:1YAG|rcsb pdb:1YVN|rcsb pdb:5NBL|rcsb pdb:5NBM|rcsb pdb:5NBN|rcsb pdb:5Y81|reactome:R-SCE-114608|reactome:R-SCE-190873|reactome:R-SCE-196025|reactome:R-SCE-2029482|reactome:R-SCE-5626467|reactome:R-SCE-5663213|reactome:R-SCE-8856828|reactome:R-SCE-8980692|reactome:R-SCE-9013026|sgd:YFL039C(identity)	-	-	crc64:87AC19B0B0BC9E71	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:+B9t0sirXq7xJD3kZIlab7KBR9Y9606	rogid:yfgwiWq/Y0HviACqgjjUugpEKLw559292	intact-crc:89C9E26714F58C44|rigid:/eNgyaKHZ+vJNnJqoJIyS8i8+6s	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P69851	uniprotkb:Q7Z6G3-2	intact:EBI-975389|uniprotkb:D6VSV2|ensemblfungi:YDR320C-A	intact:EBI-10172876|ensembl:ENSP00000457354|intact:EBI-14062040	psi-mi:dad4_yeast(display_long)|uniprotkb:Outer kinetochore protein DAD4(gene name synonym)|uniprotkb:DUO1 and DAM1-interacting protein 4(gene name synonym)|uniprotkb:Helper of ASK1 protein 2(gene name synonym)|uniprotkb:DAD4(gene name)|psi-mi:DAD4(display_short)|uniprotkb:HSK2(gene name synonym)|uniprotkb:YDR320C-A(locus name)	psi-mi:q7z6g3-2(display_long)|uniprotkb:EFCBP2(gene name synonym)|uniprotkb:Neuronal calcium-binding protein 2(gene name synonym)|uniprotkb:Synaptotagmin-interacting protein 2(gene name synonym)|uniprotkb:NECAB2(gene name)|psi-mi:NECAB2(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11534074|imex:IM-24995-1228	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YDR320C-A(gene)|ensemblfungi:YDR320C-A_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0008608"(attachment of spindle microtubules to kinetochore)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0042729"(DASH complex)|go:"GO:0051301"(cell division)|go:"GO:0051987"(positive regulation of attachment of spindle microtubules to kinetochore)|go:"GO:0072686"(mitotic spindle)|sgd:S000007604|interpro:IPR013959(DASH complex, subunit Dad4)|refseq:NP_710144.3|mint:P69851|sgd:YDR320C-A(identity)	ensembl:ENSG00000103154(gene)|ensembl:ENST00000565691(transcript)|uniprotkb:Q7Z6G3-2(isoform-parent)|intact:EBI-950070(isoform-parent)|entrezgene/locuslink:54550(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:P+GXHuoP14//+W2vOt26MEdTBNo559292	rogid:4S7oIx6h+mKzV3EPxqcfMNqaNko9606	intact-crc:252E85C7D8ED13C5|rigid:XeYySTq6AMDc79CirC718x56X1k	false	-	sufficient binding region:65-303	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UMX0	uniprotkb:P61829	intact:EBI-741480|uniprotkb:Q8IXS9|uniprotkb:Q8N2Q3|uniprotkb:Q9H0T8|uniprotkb:Q9H3R4|uniprotkb:Q9HAZ5|intact:EBI-28967608|ensembl:ENSP00000365576|uniprotkb:Q5T6J5|uniprotkb:Q5T6J9|uniprotkb:A0A024R284	intact:EBI-9016907|uniprotkb:P00841|uniprotkb:Q37750|uniprotkb:A0A0A7P075|ensemblfungi:Q0130	psi-mi:ubql1_human(display_long)|uniprotkb:Protein linking IAP with cytoskeleton 1(gene name synonym)|uniprotkb:UBQLN1(gene name)|psi-mi:UBQLN1(display_short)|uniprotkb:DA41(gene name synonym)|uniprotkb:PLIC1(gene name synonym)	psi-mi:atp9_yeast(display_long)|uniprotkb:OLI1(gene name)|psi-mi:OLI1(display_short)|uniprotkb:ATP9(gene name synonym)|uniprotkb:Lipid-binding protein(gene name synonym)|uniprotkb:OLI3(gene name synonym)|uniprotkb:Oligomycin resistance protein 1(gene name synonym)|uniprotkb:PHO2(gene name synonym)|uniprotkb:Q0130(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11534065|imex:IM-24995-1227	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000257468|ensembl:ENSP00000257468|ensembl:ENSP00000365576|ensembl:ENSG00000135018(gene)|ensembl:ENST00000376395(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000502"(proteasome complex)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016235"(aggresome)|go:"GO:0016236"(macroautophagy)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0019900"(kinase binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035973"(aggrephagy)|go:"GO:0042802"(identical protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0097352"(autophagosome maturation)|go:"GO:1901340"(negative regulation of store-operated calcium channel activity)|go:"GO:1902175"(regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)|interpro:IPR000626(Ubiquitin)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR028430|interpro:IPR029071|mint:Q9UMX0|rcsb pdb:2JY5|rcsb pdb:2JY6|rcsb pdb:2KLC|reactome:R-HSA-8856825|refseq:NP_038466.2|refseq:NP_444295.1|dip:DIP-41629N|entrezgene/locuslink:29979(identity)	reactome:R-SCE-163210|reactome:R-SCE-8949613|refseq:NP_009319.1|sgd:S000007274|refseq:YP_009144710.1|ensemblfungi:Q0130(gene)|ensemblfungi:Q0130_mRNA(transcript)|go:"GO:0000276"("mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)")|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005829"(cytosol)|go:"GO:0008289"(lipid binding)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045263"("proton-transporting ATP synthase complex, coupling factor F(o)")|interpro:IPR000454(ATPase, F0 complex, subunit C)|interpro:IPR002379(ATPase, F0/V0 complex, subunit C)|interpro:IPR020537|interpro:IPR035921|interpro:IPR038662|rcsb pdb:2WPD|rcsb pdb:2XOK|rcsb pdb:3U2F|rcsb pdb:3U2Y|rcsb pdb:3U32|rcsb pdb:3UD0|rcsb pdb:3ZRY|rcsb pdb:4B2Q|rcsb pdb:4F4S|rcsb pdb:5BPS|rcsb pdb:5BQ6|rcsb pdb:5BQA|rcsb pdb:5BQJ|rcsb pdb:6B2Z|rcsb pdb:6B8H|rcsb pdb:6CP3|rcsb pdb:6CP5|rcsb pdb:6CP6|rcsb pdb:6CP7|rcsb pdb:6WTD|dip:DIP-3041N|sgd:Q0130(identity)	-	-	crc64:82B4477D6F75D758	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:nCFfZbGCTvRYaXhQ4R99XblslvM9606	rogid:z8+f6dq67i096v23FKqgqAt3Ba4559292	intact-crc:961EA6D81E6D0862|rigid:jygzs/RZYkYaXr521b/0wzywZAs	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8IYF3-3	uniprotkb:P87108	intact:EBI-11523345|ensembl:ENSP00000363453	intact:EBI-9115|ensemblfungi:YHR005C-A|uniprotkb:D3DKU9	psi-mi:q8iyf3-3(display_long)|uniprotkb:TEX11(gene name)|psi-mi:TEX11(display_short)|uniprotkb:Protein ZIP4 homolog(gene name synonym)|uniprotkb:ZIP4(gene name synonym)	psi-mi:tim10_yeast(display_long)|uniprotkb:MRS11(gene name synonym)|uniprotkb:YHR005BC(orf name)|uniprotkb:YHR005C-A(locus name)|uniprotkb:TIM10(gene name)|psi-mi:TIM10(display_short)|uniprotkb:Mitochondrial intermembrane protein MRS11(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11534103|imex:IM-24995-1231	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000120498(gene)|ensembl:ENST00000374333(transcript)|intact:EBI-742397(isoform-parent)|uniprotkb:Q8IYF3-3(isoform-parent)|entrezgene/locuslink:56159(identity)	ensemblfungi:YHR005C-A(gene)|ensemblfungi:YHR005C-A_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0042719"(mitochondrial intermembrane space protein transporter complex)|go:"GO:0045039"(protein insertion into mitochondrial inner membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0140318"(protein transporter activity)|interpro:IPR004217(Zinc finger, Tim10/DDP-type)|interpro:IPR027100|interpro:IPR035427|rcsb pdb:3DXR|rcsb pdb:6LO8|reactome:R-SCE-1268020|refseq:NP_011869.1|sgd:S000003530|dip:DIP-1141N|mint:P87108|sgd:YHR005C-A(identity)	-	-	crc64:70DD4764B944FF17	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:PUAMFmnm5ZV2rnJ1rhm9ZeRCixg9606	rogid:3AGstULCT5EBmHEk0EGsz9Rk9YA559292	intact-crc:0B0AB0EA4D37C545|rigid:qwPzymulS4vtLWgly/ubvTgvMCU	false	sufficient binding region:9-925	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P43356	uniprotkb:P87108	intact:EBI-5650739|uniprotkb:A8K328|uniprotkb:Q32NC6|ensembl:ENSP00000333487|ensembl:ENSP00000359316|ensembl:ENSP00000469919|ensembl:ENSP00000470872|ensembl:ENSP00000480491|ensembl:ENSP00000480738|ensembl:ENSP00000484290|ensembl:ENSP00000485391|ensembl:ENSP00000485541|ensembl:ENSP00000507594|ensembl:ENSP00000507899	intact:EBI-9115|ensemblfungi:YHR005C-A|uniprotkb:D3DKU9	psi-mi:maga2_human(display_long)|uniprotkb:MAGEA2(gene name)|psi-mi:MAGEA2(display_short)|uniprotkb:MAGEA2B(gene name)|psi-mi:MAGEA2B(display_short)|uniprotkb:MAGE2(gene name synonym)|uniprotkb:MAGEA2A(gene name synonym)|uniprotkb:MAGE2(gene name synonym)|uniprotkb:MAGEA2(gene name synonym)|uniprotkb:Cancer/testis antigen 1.2(gene name synonym)|uniprotkb:MAGE-2 antigen(gene name synonym)	psi-mi:tim10_yeast(display_long)|uniprotkb:MRS11(gene name synonym)|uniprotkb:YHR005BC(orf name)|uniprotkb:YHR005C-A(locus name)|uniprotkb:TIM10(gene name)|psi-mi:TIM10(display_short)|uniprotkb:Mitochondrial intermembrane protein MRS11(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11534094|imex:IM-24995-1230	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001269430.1|refseq:NP_001269431.1|refseq:NP_001269433.1|refseq:NP_001269434.1|refseq:NP_001308329.1|refseq:NP_001308330.1|refseq:NP_001308331.1|refseq:NP_001308332.1|refseq:NP_001308333.1|refseq:NP_005352.1|refseq:NP_705692.1|refseq:NP_786884.1|refseq:NP_786885.1|dip:DIP-61231N|refseq:XP_016884895.1|refseq:XP_016885008.1|ensembl:ENSG00000183305(gene)|ensembl:ENSG00000268606(gene)|ensembl:ENST00000331220(transcript)|ensembl:ENST00000370293(transcript)|ensembl:ENST00000595583(transcript)|ensembl:ENST00000598543(transcript)|ensembl:ENST00000611557(transcript)|ensembl:ENST00000611674(transcript)|ensembl:ENST00000620710(transcript)|ensembl:ENST00000623438(transcript)|ensembl:ENST00000623806(transcript)|ensembl:ENST00000682532(transcript)|ensembl:ENST00000684311(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0016605"(PML body)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0033234"(negative regulation of protein sumoylation)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0044257"(cellular protein catabolic process)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0072331"(signal transduction by p53 class mediator)|go:"GO:0090398"(cellular senescence)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901984"(negative regulation of protein acetylation)|interpro:IPR002190(MAGE protein)|interpro:IPR021072|interpro:IPR030103|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|entrezgene/locuslink:266740(identity)	ensemblfungi:YHR005C-A(gene)|ensemblfungi:YHR005C-A_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0042719"(mitochondrial intermembrane space protein transporter complex)|go:"GO:0045039"(protein insertion into mitochondrial inner membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0140318"(protein transporter activity)|interpro:IPR004217(Zinc finger, Tim10/DDP-type)|interpro:IPR027100|interpro:IPR035427|rcsb pdb:3DXR|rcsb pdb:6LO8|reactome:R-SCE-1268020|refseq:NP_011869.1|sgd:S000003530|dip:DIP-1141N|mint:P87108|sgd:YHR005C-A(identity)	-	-	crc64:70DD4764B944FF17	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:aYv4+irEk9vGE2f3yZQR8hCQGec9606	rogid:3AGstULCT5EBmHEk0EGsz9Rk9YA559292	intact-crc:02D0DDCB81107774|rigid:m2ZGLKKYf+pz/TOU270gTTuSVIU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P69851	uniprotkb:Q9UPT5-1	intact:EBI-975389|uniprotkb:D6VSV2|ensemblfungi:YDR320C-A	intact:EBI-6251402|ensembl:ENSP00000468404	psi-mi:dad4_yeast(display_long)|uniprotkb:Outer kinetochore protein DAD4(gene name synonym)|uniprotkb:DUO1 and DAM1-interacting protein 4(gene name synonym)|uniprotkb:Helper of ASK1 protein 2(gene name synonym)|uniprotkb:DAD4(gene name)|psi-mi:DAD4(display_short)|uniprotkb:HSK2(gene name synonym)|uniprotkb:YDR320C-A(locus name)	psi-mi:q9upt5-1(display_long)|uniprotkb:EXOC7(gene name)|psi-mi:EXOC7(display_short)|uniprotkb:EXO70(gene name synonym)|uniprotkb:KIAA1067(gene name synonym)|uniprotkb:Exocyst complex component Exo70(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11534085|imex:IM-24995-1229	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YDR320C-A(gene)|ensemblfungi:YDR320C-A_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0008608"(attachment of spindle microtubules to kinetochore)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0042729"(DASH complex)|go:"GO:0051301"(cell division)|go:"GO:0051987"(positive regulation of attachment of spindle microtubules to kinetochore)|go:"GO:0072686"(mitotic spindle)|sgd:S000007604|interpro:IPR013959(DASH complex, subunit Dad4)|refseq:NP_710144.3|mint:P69851|sgd:YDR320C-A(identity)	ensembl:ENSG00000182473(gene)|ensembl:ENST00000589210(transcript)|intact:EBI-720048(isoform-parent)|uniprotkb:Q9UPT5-1(isoform-parent)|entrezgene/locuslink:23265(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:P+GXHuoP14//+W2vOt26MEdTBNo559292	rogid:CKIeTOGXIWrHA1Duuw7x1ycRPoc9606	intact-crc:441642E5A3194C88|rigid:Dz3cuiQPy1CeDZl+jtjPoiO0azk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q5VWN6	uniprotkb:P89105	intact:EBI-745958|uniprotkb:Q2YD91|uniprotkb:Q5VWN5|uniprotkb:Q6ZRQ8|uniprotkb:Q8IVG4|uniprotkb:Q9BUZ7|uniprotkb:Q9H5J9|uniprotkb:Q9H7A4|uniprotkb:Q9H996|uniprotkb:Q9NXA1|intact:EBI-28974916|ensembl:ENSP00000328426	intact:EBI-5283|uniprotkb:O14409|uniprotkb:Q07332|uniprotkb:Q08292|uniprotkb:D6W1S4|ensemblfungi:YOL145C	psi-mi:taso2_human(display_long)|uniprotkb:TASOR2(gene name)|psi-mi:TASOR2(display_short)|uniprotkb:C10orf18(gene name synonym)|uniprotkb:FAM208B(gene name synonym)|uniprotkb:KIAA2006(gene name synonym)	psi-mi:ctr9_yeast(display_long)|uniprotkb:CTR9(gene name)|psi-mi:CTR9(display_short)|uniprotkb:CDP1(gene name synonym)|uniprotkb:Cln three-requiring protein 9(gene name synonym)|uniprotkb:Centromere-binding factor 1-dependent protein 1(gene name synonym)|uniprotkb:YOL145C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11534123|imex:IM-24995-1233	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060252.4|ensembl:ENSP00000328426|refseq:XP_011517827.1|refseq:XP_016871852.1|refseq:XP_016871854.1|ensembl:ENSG00000108021(gene)|ensembl:ENST00000328090(transcript)|go:"GO:0005829"(cytosol)|interpro:IPR022168|interpro:IPR022188|mint:Q5VWN6|go:"GO:0005654"(nucleoplasm)|refseq:XP_005252532.1|refseq:XP_005252537.1|refseq:XP_005252538.1|refseq:XP_005252539.1|refseq:NP_001308712.1|refseq:NP_001308713.1|refseq:NP_001308714.1|entrezgene/locuslink:54906(identity)	refseq:NP_014496.2|sgd:S000005505|dip:DIP-2814N|mint:P89105|ensemblfungi:YOL145C(gene)|ensemblfungi:YOL145C_mRNA(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001015"(snoRNA transcription by RNA polymerase II)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006362"(transcription elongation from RNA polymerase I promoter)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016570"(histone modification)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0031126"("sno(s)RNA 3'-end processing")|go:"GO:0031938"(obsolete regulation of chromatin silencing at telomere)|go:"GO:0035327"|go:"GO:0045142"(triplex DNA binding)|go:"GO:0051569"(regulation of histone H3-K4 methylation)|go:"GO:0060260"(regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0090262"(regulation of transcription-coupled nucleotide-excision repair)|go:"GO:1901525"(negative regulation of mitophagy)|go:"GO:1990269"(RNA polymerase II C-terminal domain phosphoserine binding)|go:"GO:2001165"(positive regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues)|go:"GO:2001173"(regulation of histone H2B conserved C-terminal lysine ubiquitination)|go:"GO:2001209"(positive regulation of transcription elongation from RNA polymerase I promoter)|go:"GO:2001255"(positive regulation of histone H3-K36 trimethylation)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR031101|rcsb pdb:5ZYP|reactome:R-SCE-674695|reactome:R-SCE-75955|sgd:YOL145C(identity)	-	-	crc64:F794ECBAD26D4820	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:mTRMzWB45dZojaB1ZrsaQRT48YQ9606	rogid:85qAqldtQL8T7JBgNxrvAYtHhd0559292	intact-crc:33E5E0A2279CAA81|rigid:FxzaTQsvu4zvbC5gJ0sb6VL7IaU	false	sufficient binding region:1690-2430	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P89105	uniprotkb:Q14596-2	intact:EBI-5283|uniprotkb:O14409|uniprotkb:Q07332|uniprotkb:Q08292|uniprotkb:D6W1S4|ensemblfungi:YOL145C	intact:EBI-11081753|ensembl:ENSP00000467816	psi-mi:ctr9_yeast(display_long)|uniprotkb:CTR9(gene name)|psi-mi:CTR9(display_short)|uniprotkb:CDP1(gene name synonym)|uniprotkb:Cln three-requiring protein 9(gene name synonym)|uniprotkb:Centromere-binding factor 1-dependent protein 1(gene name synonym)|uniprotkb:YOL145C(locus name)	psi-mi:q14596-2(display_long)|uniprotkb:NBR1(gene name)|psi-mi:NBR1(display_short)|uniprotkb:1A13B(gene name synonym)|uniprotkb:Cell migration-inducing gene 19 protein(gene name synonym)|uniprotkb:KIAA0049(gene name synonym)|uniprotkb:M17S2(gene name synonym)|uniprotkb:Membrane component chromosome 17 surface marker 2(gene name synonym)|uniprotkb:Neighbor of BRCA1 gene 1 protein(gene name synonym)|uniprotkb:Protein 1A1-3B(gene name synonym)|uniprotkb:MIG19(orf name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11534114|imex:IM-24995-1232	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014496.2|sgd:S000005505|dip:DIP-2814N|mint:P89105|ensemblfungi:YOL145C(gene)|ensemblfungi:YOL145C_mRNA(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001015"(snoRNA transcription by RNA polymerase II)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006362"(transcription elongation from RNA polymerase I promoter)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016570"(histone modification)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0031126"("sno(s)RNA 3'-end processing")|go:"GO:0031938"(obsolete regulation of chromatin silencing at telomere)|go:"GO:0035327"|go:"GO:0045142"(triplex DNA binding)|go:"GO:0051569"(regulation of histone H3-K4 methylation)|go:"GO:0060260"(regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0090262"(regulation of transcription-coupled nucleotide-excision repair)|go:"GO:1901525"(negative regulation of mitophagy)|go:"GO:1990269"(RNA polymerase II C-terminal domain phosphoserine binding)|go:"GO:2001165"(positive regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues)|go:"GO:2001173"(regulation of histone H2B conserved C-terminal lysine ubiquitination)|go:"GO:2001209"(positive regulation of transcription elongation from RNA polymerase I promoter)|go:"GO:2001255"(positive regulation of histone H3-K36 trimethylation)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR031101|rcsb pdb:5ZYP|reactome:R-SCE-674695|reactome:R-SCE-75955|sgd:YOL145C(identity)	intact:EBI-742698(isoform-parent)|ensembl:ENSG00000188554(gene)|ensembl:ENST00000589872(transcript)|uniprotkb:Q14596-2(isoform-parent)|entrezgene/locuslink:4077(identity)	-	crc64:F794ECBAD26D4820	isoform-comment:No experimental confirmation available.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:85qAqldtQL8T7JBgNxrvAYtHhd0559292	rogid:KrZKoabpN1yOvD3Bt6+CCN9Wv5g9606	intact-crc:D2F797DF2A9D65E3|rigid:LG3mv+dbVjN5SNCITI1CYwWPwyY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q01590	uniprotkb:Q8N6L0	intact:EBI-16930|uniprotkb:D6VY28|ensemblfungi:YLR026C	intact:EBI-749265|uniprotkb:Q96MC3|ensembl:ENSP00000404220	psi-mi:sed5_yeast(display_long)|uniprotkb:SED5(gene name)|psi-mi:SED5(display_short)|uniprotkb:YLR026C(locus name)	psi-mi:kash5_human(display_long)|uniprotkb:KASH5(gene name)|psi-mi:KASH5(display_short)|uniprotkb:CCDC155(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 155(gene name synonym)|uniprotkb:KASH domain-containing protein 5(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11534163|imex:IM-24995-1237	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013126.1|sgd:S000004016|ensemblfungi:YLR026C(gene)|ensemblfungi:YLR026C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0006906"(vesicle fusion)|go:"GO:0090083"(regulation of inclusion body assembly)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|interpro:IPR021538|rcsb pdb:1MQS|rcsb pdb:1PD0|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|reactome:R-SCE-204005|reactome:R-SCE-5694530|reactome:R-SCE-6807878|reactome:R-SCE-6811438|reactome:R-SCE-9609523|go:"GO:0031201"(SNARE complex)|go:"GO:0048278"(vesicle docking)|go:"GO:0048280"(vesicle fusion with Golgi apparatus)|dip:DIP-2489N|mint:Q01590|sgd:YLR026C(identity)	refseq:NP_653289.3|ensembl:ENSG00000161609(gene)|ensembl:ENST00000447857(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034397"(telomere localization)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051225"(spindle assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0090172"(microtubule cytoskeleton organization involved in homologous chromosome segregation)|go:"GO:0090220"(chromosome localization to nuclear envelope involved in homologous chromosome segregation)|go:"GO:0090619"(meiotic spindle pole)|interpro:IPR011992(EF-Hand type)|interpro:IPR028168|interpro:IPR028170|interpro:IPR039508|mint:Q8N6L0|rcsb pdb:6R2I|rcsb pdb:6WMF|entrezgene/locuslink:147872(identity)	-	crc64:B3192B57269A0B83	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:c+W+86qfjxcvWWJ9nMScyH5TjNA559292	rogid:Wl9L7AcvDHCZuKjYLn8QgGIbZTc9606	intact-crc:64CC7B4E114D2CD5|rigid:Tz4PxmOiFDvWjE8O6ssbXUTVHDA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q01589	uniprotkb:O95994	intact:EBI-16917|uniprotkb:D6VS63|uniprotkb:Q6Q5U8|uniprotkb:Q8J057|uniprotkb:Q8J270|uniprotkb:Q8J271|uniprotkb:Q8J272|uniprotkb:Q8J273|uniprotkb:Q8J274|uniprotkb:Q8J275|ensemblfungi:YDR077W	intact:EBI-712648|ensembl:ENSP00000391490	psi-mi:sed1_yeast(display_long)|uniprotkb:SED1(gene name)|psi-mi:SED1(display_short)|uniprotkb:YDR077W(locus name)|uniprotkb:D4431(orf name)|uniprotkb:Glycoprotein GP260(gene name synonym)	psi-mi:agr2_human(display_long)|uniprotkb:Secreted cement gland protein XAG-2 homolog(gene name synonym)|uniprotkb:HPC8(gene name synonym)|uniprotkb:AG2(gene name synonym)|uniprotkb:UNQ515/PRO1030(orf name)|uniprotkb:AGR2(gene name)|psi-mi:AGR2(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11534154|imex:IM-24995-1236	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010362.3|sgd:S000002484|ensemblfungi:YDR077W(gene)|ensemblfungi:YDR077W_mRNA(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0005199"(structural constituent of cell wall)|go:"GO:0005576"(extracellular region)|go:"GO:0005739"(mitochondrion)|go:"GO:0005840"(ribosome)|go:"GO:0009277"(fungal-type cell wall)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0071944"(cell periphery)|interpro:IPR038843|dip:DIP-1613N|sgd:YDR077W(identity)	go:"GO:0005615"(extracellular space)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0042802"(identical protein binding)|go:"GO:0045742"(positive regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0048546"(digestive tract morphogenesis)|go:"GO:0048639"(positive regulation of developmental growth)|go:"GO:0060480"(lung goblet cell differentiation)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070254"(mucus secretion)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:1903896"(positive regulation of IRE1-mediated unfolded protein response)|go:"GO:1903899"(positive regulation of PERK-mediated unfolded protein response)|interpro:IPR036249|rcsb pdb:2LNS|rcsb pdb:2LNT|ensembl:ENSG00000106541(gene)|ensembl:ENST00000419304(transcript)|go:"GO:0002162"(dystroglycan binding)|go:"GO:0005154"(epidermal growth factor receptor binding)|refseq:NP_006399.1|refseq:XP_005249638.1|dip:DIP-48825N|entrezgene/locuslink:10551(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:4Oyb3fialIFuwCLzsRFRcTML3ng559292	rogid:E824a1MDXuGzk23ohjS7HAeEx5U9606	intact-crc:47176A08F63EFBC3|rigid:+Og9Ak04gZMAOLZ+h81rO514dHk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q00618	uniprotkb:O76083-2	intact:EBI-3573|uniprotkb:D6VWF1|ensemblfungi:YJL031C	intact:EBI-11524542|ensembl:ENSP00000335242	psi-mi:pgta_yeast(display_long)|uniprotkb:Geranylgeranyl transferase type II subunit alpha(gene name synonym)|uniprotkb:Type II protein geranyl-geranyltransferase subunit alpha(gene name synonym)|uniprotkb:PGGT(gene name synonym)|uniprotkb:YPT1/SEC4 proteins geranylgeranyltransferase subunit alpha(gene name synonym)|uniprotkb:GGTase-II-alpha(gene name synonym)|uniprotkb:BET4(gene name)|psi-mi:BET4(display_short)|uniprotkb:YJL031C(locus name)|uniprotkb:J1254(orf name)	psi-mi:o76083-2(display_long)|uniprotkb:PDE9A(gene name)|psi-mi:PDE9A(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11534143|imex:IM-24995-1235	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012503.2|sgd:S000003568|reactome:R-SCE-6803205|reactome:R-SCE-8873719|dip:DIP-4994N|ensemblfungi:YJL031C(gene)|ensemblfungi:YJL031C_mRNA(transcript)|go:"GO:0004663"(Rab geranylgeranyltransferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005777"(peroxisome)|go:"GO:0005829"(cytosol)|go:"GO:0005968"(Rab-protein geranylgeranyltransferase complex)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0018344"(protein geranylgeranylation)|go:"GO:0031267"(small GTPase binding)|interpro:IPR002088(Protein prenyltransferase, alpha subunit)|interpro:IPR032955|sgd:YJL031C(identity)	intact:EBI-742764(isoform-parent)|ensembl:ENSG00000160191(gene)|ensembl:ENST00000335512(transcript)|uniprotkb:O76083-2(isoform-parent)|entrezgene/locuslink:5152(identity)	-	crc64:A7C3E16C14DDD09C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:xjJwfQovYxV3BOkX1NVrOXxq/PM559292	rogid:nTzgeYGOwTM/7VJUgxSnlnDiCFo9606	intact-crc:08C1140737562569|rigid:w0s0D19GLkafzdPDwaSttgLhW14	false	sufficient binding region:38-327	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P89886	uniprotkb:O43583	intact:EBI-33141|uniprotkb:D3DLQ4|ensemblfungi:YER007C-A	intact:EBI-716083|uniprotkb:Q9H3U6|uniprotkb:Q9UKZ0|ensembl:ENSP00000280557	psi-mi:tma20_yeast(display_long)|uniprotkb:TMA20(gene name)|psi-mi:TMA20(display_short)|uniprotkb:YER007C-A(locus name)	psi-mi:denr_human(display_long)|uniprotkb:Protein DRP1(gene name synonym)|uniprotkb:Smooth muscle cell-associated protein 3(gene name synonym)|uniprotkb:DENR(gene name)|psi-mi:DENR(display_short)|uniprotkb:DRP1(gene name synonym)|uniprotkb:H14(orf name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11534134|imex:IM-24995-1234	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002957|refseq:NP_010923.3|mint:P89886|dip:DIP-1841N|ensemblfungi:YER007C-A(gene)|ensemblfungi:YER007C-A_mRNA(transcript)|go:"GO:0001731"(formation of translation preinitiation complex)|go:"GO:0002188"(translation reinitiation)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0042254"(ribosome biogenesis)|interpro:IPR002478(PUA)|interpro:IPR004521(Uncharacterized domain 2)|interpro:IPR015947(PUA-like)|interpro:IPR016437(Translation machinery-associated RNA binding protein, predicted)|interpro:IPR041366|sgd:YER007C-A(identity)	refseq:NP_003668.2|go:"GO:0075522"(IRES-dependent viral translational initiation)|interpro:IPR001950(Translation initiation factor SUI1)|interpro:IPR005873(Density-regulated protein DRP1)|interpro:IPR036877|go:"GO:0032790"(ribosome disassembly)|mint:O43583|rcsb pdb:5ONS|rcsb pdb:5VYC|rcsb pdb:6MS4|rcsb pdb:6VPQ|rcsb pdb:6VPR|ensembl:ENSG00000139726(gene)|ensembl:ENST00000280557(transcript)|go:"GO:0001731"(formation of translation preinitiation complex)|go:"GO:0002188"(translation reinitiation)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|entrezgene/locuslink:8562(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:vBHXl1594jcHQvXHu/MCy4G6U4c559292	rogid:pZLEnnYWNEai+gZ/jD+Rt9B6j2E9606	intact-crc:710D3C6CBE9A9886|rigid:lI9/Vn8gtSU8OSadw26o/6OpIBo	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P98170	uniprotkb:Q01976	intact:EBI-517127|uniprotkb:Q9NQ14|uniprotkb:D3DTF2|ensembl:ENSP00000347858|ensembl:ENSP00000360242|ensembl:ENSP00000395230	intact:EBI-2344265|uniprotkb:D6VQB0|ensemblfungi:YBR111C	psi-mi:xiap_human(display_long)|uniprotkb:Inhibitor of apoptosis protein 3(gene name synonym)|uniprotkb:X-linked inhibitor of apoptosis protein(gene name synonym)|uniprotkb:IAP-like protein(gene name synonym)|uniprotkb:XIAP(gene name)|psi-mi:XIAP(display_short)|uniprotkb:API3(gene name synonym)|uniprotkb:IAP3(gene name synonym)|uniprotkb:BIRC4(gene name synonym)|uniprotkb:Baculoviral IAP repeat-containing protein 4(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase XIAP(gene name synonym)	psi-mi:adpp_yeast(display_long)|uniprotkb:YSA1(gene name)|psi-mi:YSA1(display_short)|uniprotkb:ADP-ribose diphosphatase(gene name synonym)|uniprotkb:Adenosine diphosphoribose pyrophosphatase(gene name synonym)|uniprotkb:ADP-ribose phosphohydrolase(gene name synonym)|uniprotkb:YBR0907(orf name)|uniprotkb:YBR111C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11534192|imex:IM-24995-1240	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006724817.1|refseq:NP_001158.2|refseq:NP_001191330.1|refseq:XP_011529631.1|dip:DIP-27626N|ensembl:ENSG00000101966(gene)|ensembl:ENST00000355640(transcript)|ensembl:ENST00000371199(transcript)|ensembl:ENST00000434753(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005876"(spindle microtubule)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030510"(regulation of BMP signaling pathway)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0055070"(copper ion homeostasis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070424"(regulation of nucleotide-binding oligomerization domain containing signaling pathway)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:1902530"(positive regulation of protein linear polyubiquitination)|go:"GO:1990001"(inhibition of cysteine-type endopeptidase activity involved in apoptotic process)|interpro:IPR001370(Proteinase inhibitor I32, inhibitor of apoptosis)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011029(DEATH-like)|interpro:IPR042579|mint:P98170|rcsb pdb:1C9Q|rcsb pdb:1F9X|rcsb pdb:1G3F|rcsb pdb:1G73|rcsb pdb:1I3O|rcsb pdb:1I4O|rcsb pdb:1I51|rcsb pdb:1KMC|rcsb pdb:1NW9|rcsb pdb:1TFQ|rcsb pdb:1TFT|rcsb pdb:2ECG|rcsb pdb:2JK7|rcsb pdb:2KNA|rcsb pdb:2OPY|rcsb pdb:2OPZ|rcsb pdb:2POI|rcsb pdb:2POP|rcsb pdb:2QRA|rcsb pdb:2VSL|rcsb pdb:3CLX|rcsb pdb:3CM2|rcsb pdb:3CM7|rcsb pdb:3EYL|rcsb pdb:3G76|rcsb pdb:3HL5|rcsb pdb:3UW4|rcsb pdb:3UW5|rcsb pdb:4EC4|rcsb pdb:4HY0|rcsb pdb:4IC2|rcsb pdb:4IC3|rcsb pdb:4J3Y|rcsb pdb:4J44|rcsb pdb:4J45|rcsb pdb:4J46|rcsb pdb:4J47|rcsb pdb:4J48|rcsb pdb:4KJU|rcsb pdb:4KJV|rcsb pdb:4KMP|rcsb pdb:4MTZ|rcsb pdb:4OXC|rcsb pdb:4WVS|rcsb pdb:4WVT|rcsb pdb:4WVU|rcsb pdb:5C0K|rcsb pdb:5C0L|rcsb pdb:5C3H|rcsb pdb:5C3K|rcsb pdb:5C7A|rcsb pdb:5C7B|rcsb pdb:5C7C|rcsb pdb:5C7D|rcsb pdb:5C83|rcsb pdb:5C84|rcsb pdb:5M6E|rcsb pdb:5M6F|rcsb pdb:5M6H|rcsb pdb:5M6L|rcsb pdb:5M6M|rcsb pdb:5O6T|rcsb pdb:5OQW|rcsb pdb:6EY2|rcsb pdb:6GJW|rcsb pdb:6QCI|reactome:R-HSA-111459|reactome:R-HSA-111463|reactome:R-HSA-111464|reactome:R-HSA-111469|reactome:R-HSA-3769402|reactome:R-HSA-5213460|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5675482|reactome:R-HSA-8948747|reactome:R-HSA-8948751|reactome:R-HSA-9627069|entrezgene/locuslink:331(identity)	refseq:NP_009669.1|sgd:S000000315|interpro:IPR020084|interpro:IPR000086(NUDIX hydrolase, core)|interpro:IPR015797(NUDIX)|reactome:R-SCE-2393930|ensemblfungi:YBR111C(gene)|ensemblfungi:YBR111C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006753"(nucleoside phosphate metabolic process)|go:"GO:0019693"(ribose phosphate metabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0047631"(ADP-ribose diphosphatase activity)|sgd:YBR111C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:6eDcOay+c2ZmIAD/pwnCDROBwgM9606	rogid:tpdVT9ttt/pL+UevSr0zW+rfyIc559292	intact-crc:49AB9C2B7C02813C|rigid:G4yBzu9FXOxAZj65iK+olxZAd+g	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q01976	uniprotkb:G5E962	intact:EBI-2344265|uniprotkb:D6VQB0|ensemblfungi:YBR111C	intact:EBI-11525615|ensembl:ENSP00000328177	psi-mi:adpp_yeast(display_long)|uniprotkb:YSA1(gene name)|psi-mi:YSA1(display_short)|uniprotkb:ADP-ribose diphosphatase(gene name synonym)|uniprotkb:Adenosine diphosphoribose pyrophosphatase(gene name synonym)|uniprotkb:ADP-ribose phosphohydrolase(gene name synonym)|uniprotkb:YBR0907(orf name)|uniprotkb:YBR111C(locus name)	psi-mi:g5e962_human(display_long)|uniprotkb:hCG_1644200(orf name)|uniprotkb:MAGEA11(gene name)|psi-mi:MAGEA11(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11534181|imex:IM-24995-1239	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009669.1|sgd:S000000315|interpro:IPR020084|interpro:IPR000086(NUDIX hydrolase, core)|interpro:IPR015797(NUDIX)|reactome:R-SCE-2393930|ensemblfungi:YBR111C(gene)|ensemblfungi:YBR111C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006753"(nucleoside phosphate metabolic process)|go:"GO:0019693"(ribose phosphate metabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0047631"(ADP-ribose diphosphatase activity)|sgd:YBR111C(identity)	refseq:NP_001011544.1|ensembl:ENSG00000185247(gene)|ensembl:ENST00000333104(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016604"(nuclear body)|interpro:IPR002190(MAGE protein)|interpro:IPR021072|interpro:IPR030099|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|entrezgene/locuslink:4110(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:tpdVT9ttt/pL+UevSr0zW+rfyIc559292	rogid:sVB0aA6yibWUx/d2SE+pwpKKgtI9606	intact-crc:01CEEA85E19CB3F4|rigid:+oIfTL7Jn2G8+m/q4jryuXjkY8U	false	-	sufficient binding region:82-400	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q01590	uniprotkb:Q9UI14	intact:EBI-16930|uniprotkb:D6VY28|ensemblfungi:YLR026C	intact:EBI-712367|ensembl:ENSP00000222008|uniprotkb:Q7Z4Y2|uniprotkb:Q9Y3R1	psi-mi:sed5_yeast(display_long)|uniprotkb:SED5(gene name)|psi-mi:SED5(display_short)|uniprotkb:YLR026C(locus name)	psi-mi:praf1_human(display_long)|uniprotkb:PRA1 family protein 1(gene name synonym)|uniprotkb:RABAC1(gene name)|psi-mi:RABAC1(display_short)|uniprotkb:PRA1(gene name synonym)|uniprotkb:PRAF1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11534172|imex:IM-24995-1238	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013126.1|sgd:S000004016|ensemblfungi:YLR026C(gene)|ensemblfungi:YLR026C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0006906"(vesicle fusion)|go:"GO:0090083"(regulation of inclusion body assembly)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|interpro:IPR021538|rcsb pdb:1MQS|rcsb pdb:1PD0|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|reactome:R-SCE-204005|reactome:R-SCE-5694530|reactome:R-SCE-6807878|reactome:R-SCE-6811438|reactome:R-SCE-9609523|go:"GO:0031201"(SNARE complex)|go:"GO:0048278"(vesicle docking)|go:"GO:0048280"(vesicle fusion with Golgi apparatus)|dip:DIP-2489N|mint:Q01590|sgd:YLR026C(identity)	refseq:NP_006414.2|ensembl:ENSG00000105404(gene)|ensembl:ENST00000222008(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0070064"(proline-rich region binding)|interpro:IPR004895(Prenylated rab acceptor PRA1)|mint:Q9UI14|entrezgene/locuslink:10567(identity)	-	crc64:B3192B57269A0B83	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:c+W+86qfjxcvWWJ9nMScyH5TjNA559292	rogid:WS2rUY7yXRbR7pqWgfUCbnEiDbg9606	intact-crc:4AA88F2E9E9C6413|rigid:RgVmkjyaRYAZv3poNv9+Q5mqOo4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q02256	uniprotkb:Q9Y5P8-2	intact:EBI-14322|uniprotkb:D6VVV7|ensemblfungi:YIR026C	intact:EBI-11534240	psi-mi:pvh1_yeast(display_long)|uniprotkb:YIR026C(locus name)|uniprotkb:YVH1(gene name)|psi-mi:YVH1(display_short)	psi-mi:q9y5p8-2(display_long)|uniprotkb:PP2A subunit B isoform PR48(gene name synonym)|uniprotkb:PPP2R3L(gene name synonym)|uniprotkb:Protein phosphatase 2A 48 kDa regulatory subunit(gene name synonym)|uniprotkb:PPP2R3B(gene name)|psi-mi:PPP2R3B(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11534238|imex:IM-24995-1245	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YIR026C_mRNA(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|ensemblfungi:YIR026C(gene)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0008138"(protein tyrosine/serine/threonine phosphatase activity)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0030476"(ascospore wall assembly)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:1990275"(preribosome binding)|go:"GO:2000786"(positive regulation of autophagosome assembly)|interpro:IPR000340(Protein-tyrosine phosphatase, dual specificity)|interpro:IPR000387(Protein-tyrosine phosphatase)|sgd:S000001465|interpro:IPR020422|interpro:IPR029021|rcsb pdb:6N8M|interpro:IPR016278(Tyrosine protein phosphatase, dual specificity, 12)|rcsb pdb:6N8N|rcsb pdb:6N8O|rcsb pdb:6RZZ|rcsb pdb:6S05|refseq:NP_012292.3|mint:Q02256|dip:DIP-5192N|sgd:YIR026C(identity)	intact:EBI-2479826(isoform-parent)|entrezgene/locuslink:28227(identity)	-	crc64:9E75C7CC14353B43	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:9C9+S3aubsVjSLE5Kklpws+PA0A559292	rogid:u/vhz15um2LQ5BCN/pXjf+NVCTc9606	intact-crc:AEBCF2A190C7E10B|rigid:VWGXq5x4MxFS/EKpecUkXmORX84	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9HCM9-2	uniprotkb:Q02209	intact:EBI-11523450|ensembl:ENSP00000365847|ensembl:ENSP00000373095|ensembl:ENSP00000373097|ensembl:ENSP00000379797|ensembl:ENSP00000379800|ensembl:ENSP00000383486|ensembl:ENSP00000387445|ensembl:ENSP00000389198|ensembl:ENSP00000389852|ensembl:ENSP00000392130|ensembl:ENSP00000394353|ensembl:ENSP00000396986|ensembl:ENSP00000398956|ensembl:ENSP00000401071|ensembl:ENSP00000401184|ensembl:ENSP00000404340|ensembl:ENSP00000404904|ensembl:ENSP00000411582|ensembl:ENSP00000412743|ensembl:ENSP00000414525|ensembl:ENSP00000415259	intact:EBI-27066|uniprotkb:D6VX77|ensemblfungi:YKR011C	psi-mi:q9hcm9-2(display_long)|uniprotkb:TRIM39(gene name)|psi-mi:TRIM39(display_short)|uniprotkb:RING finger protein 23(gene name synonym)|uniprotkb:RNF23(gene name synonym)|uniprotkb:TFP(gene name synonym)|uniprotkb:Testis-abundant finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 39(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM39(gene name synonym)|uniprotkb:TIM39beta(isoform synonym)	psi-mi:ykz1_yeast(display_long)|uniprotkb:YK110(orf name)|uniprotkb:YKR011C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11534228|imex:IM-24995-1244	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-739510(isoform-parent)|ensembl:ENSG00000204599(gene)|ensembl:ENSG00000206495(gene)|ensembl:ENSG00000224994(gene)|ensembl:ENSG00000226437(gene)|ensembl:ENSG00000229929(gene)|ensembl:ENSG00000230308(gene)|ensembl:ENSG00000232839(gene)|ensembl:ENST00000376659(transcript)|ensembl:ENST00000383601(transcript)|ensembl:ENST00000383603(transcript)|ensembl:ENST00000396548(transcript)|ensembl:ENST00000396551(transcript)|ensembl:ENST00000400644(transcript)|ensembl:ENST00000414015(transcript)|ensembl:ENST00000419790(transcript)|ensembl:ENST00000430502(transcript)|ensembl:ENST00000431272(transcript)|ensembl:ENST00000433900(transcript)|ensembl:ENST00000438076(transcript)|ensembl:ENST00000438859(transcript)|ensembl:ENST00000440117(transcript)|ensembl:ENST00000443109(transcript)|ensembl:ENST00000446397(transcript)|ensembl:ENST00000449318(transcript)|ensembl:ENST00000450778(transcript)|ensembl:ENST00000451132(transcript)|ensembl:ENST00000452705(transcript)|ensembl:ENST00000458607(transcript)|uniprotkb:Q9HCM9-2(isoform-parent)|entrezgene/locuslink:56658(identity)	sgd:S000001719|refseq:NP_012936.1|mint:Q02209|dip:DIP-1923N|ensemblfungi:YKR011C(gene)|ensemblfungi:YKR011C_mRNA(transcript)|go:"GO:0005634"(nucleus)|sgd:YKR011C(identity)	-	-	crc64:785423803C0EAD6A	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:UfSn2+IVRxtGomVeDGdZpL7mz5I9606	rogid:DWbgg9PhX711mFipd/pvqT970D4559292	intact-crc:BAA051C16E78E604|rigid:4pCUiK7bgdX8xPoHVTffVv/B03Q	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q01976	uniprotkb:Q9UGJ1-2	intact:EBI-2344265|uniprotkb:D6VQB0|ensemblfungi:YBR111C	intact:EBI-10964469|ensembl:ENSP00000456648	psi-mi:adpp_yeast(display_long)|uniprotkb:YSA1(gene name)|psi-mi:YSA1(display_short)|uniprotkb:ADP-ribose diphosphatase(gene name synonym)|uniprotkb:Adenosine diphosphoribose pyrophosphatase(gene name synonym)|uniprotkb:ADP-ribose phosphohydrolase(gene name synonym)|uniprotkb:YBR0907(orf name)|uniprotkb:YBR111C(locus name)	psi-mi:q9ugj1-2(display_long)|uniprotkb:TUBGCP4(gene name)|psi-mi:TUBGCP4(display_short)|uniprotkb:76P(gene name synonym)|uniprotkb:GCP4(gene name synonym)|uniprotkb:Gamma-ring complex protein 76 kDa(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11534219|imex:IM-24995-1243	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009669.1|sgd:S000000315|interpro:IPR020084|interpro:IPR000086(NUDIX hydrolase, core)|interpro:IPR015797(NUDIX)|reactome:R-SCE-2393930|ensemblfungi:YBR111C(gene)|ensemblfungi:YBR111C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006753"(nucleoside phosphate metabolic process)|go:"GO:0019693"(ribose phosphate metabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0047631"(ADP-ribose diphosphatase activity)|sgd:YBR111C(identity)	intact:EBI-1052544(isoform-parent)|ensembl:ENSG00000137822(gene)|ensembl:ENST00000564079(transcript)|uniprotkb:Q9UGJ1-2(isoform-parent)|entrezgene/locuslink:27229(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:tpdVT9ttt/pL+UevSr0zW+rfyIc559292	rogid:+lfeIRS3N2OU1+y84kUyKY7ePNA9606	intact-crc:8E50FF164A5918D8|rigid:Nl6vjWQsboG3a+WfLlabYcKtJaI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q01976	uniprotkb:Q9H8Y8	intact:EBI-2344265|uniprotkb:D6VQB0|ensemblfungi:YBR111C	intact:EBI-739467|uniprotkb:Q96I74|uniprotkb:Q96K84|uniprotkb:Q9H946|uniprotkb:Q9UFW4|uniprotkb:Q53TE3|intact:EBI-28970723|uniprotkb:B4DKT0|ensembl:ENSP00000234160	psi-mi:adpp_yeast(display_long)|uniprotkb:YSA1(gene name)|psi-mi:YSA1(display_short)|uniprotkb:ADP-ribose diphosphatase(gene name synonym)|uniprotkb:Adenosine diphosphoribose pyrophosphatase(gene name synonym)|uniprotkb:ADP-ribose phosphohydrolase(gene name synonym)|uniprotkb:YBR0907(orf name)|uniprotkb:YBR111C(locus name)	psi-mi:gors2_human(display_long)|uniprotkb:GORASP2(gene name)|psi-mi:GORASP2(display_short)|uniprotkb:Golgi reassembly-stacking protein of 55 kDa(gene name synonym)|uniprotkb:p59(gene name synonym)|uniprotkb:Golgi phosphoprotein 6(gene name synonym)|uniprotkb:GOLPH6(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11534210|imex:IM-24995-1242	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009669.1|sgd:S000000315|interpro:IPR020084|interpro:IPR000086(NUDIX hydrolase, core)|interpro:IPR015797(NUDIX)|reactome:R-SCE-2393930|ensemblfungi:YBR111C(gene)|ensemblfungi:YBR111C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006753"(nucleoside phosphate metabolic process)|go:"GO:0019693"(ribose phosphate metabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0047631"(ADP-ribose diphosphatase activity)|sgd:YBR111C(identity)	ensembl:ENSP00000234160|refseq:NP_001188357.1|refseq:NP_056345.3|refseq:XP_006712471.1|ensembl:ENSG00000115806(gene)|ensembl:ENST00000234160(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006996"(organelle organization)|go:"GO:0007030"(Golgi organization)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016020"(membrane)|go:"GO:0030154"(cell differentiation)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0061951"(establishment of protein localization to plasma membrane)|go:"GO:0070925"(organelle assembly)|interpro:IPR007583(GRASP55/65)|interpro:IPR024958|interpro:IPR036034|mint:Q9H8Y8|rcsb pdb:3RLE|rcsb pdb:4EDJ|reactome:R-HSA-162658|entrezgene/locuslink:26003(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:tpdVT9ttt/pL+UevSr0zW+rfyIc559292	rogid:xSy3HsObmteg/doer5eLoZiz+fU9606	intact-crc:8B3D07E53E7B08AA|rigid:OHa3n2x9t+6nqKgGZYVRAB//z5Q	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q13490	uniprotkb:Q01976	intact:EBI-514538|uniprotkb:Q16516|uniprotkb:Q4TTG0|uniprotkb:B4E026|ensembl:ENSP00000227758|ensembl:ENSP00000477613	intact:EBI-2344265|uniprotkb:D6VQB0|ensemblfungi:YBR111C	psi-mi:birc2_human(display_long)|uniprotkb:Inhibitor of apoptosis protein 2(gene name synonym)|uniprotkb:TNFR2-TRAF-signaling complex protein 2(gene name synonym)|uniprotkb:IAP homolog B(gene name synonym)|uniprotkb:RING finger protein 48(gene name synonym)|uniprotkb:BIRC2(gene name)|psi-mi:BIRC2(display_short)|uniprotkb:API1(gene name synonym)|uniprotkb:MIHB(gene name synonym)|uniprotkb:RNF48(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase BIRC2(gene name synonym)|uniprotkb:Cellular inhibitor of apoptosis 1(gene name synonym)	psi-mi:adpp_yeast(display_long)|uniprotkb:YSA1(gene name)|psi-mi:YSA1(display_short)|uniprotkb:ADP-ribose diphosphatase(gene name synonym)|uniprotkb:Adenosine diphosphoribose pyrophosphatase(gene name synonym)|uniprotkb:ADP-ribose phosphohydrolase(gene name synonym)|uniprotkb:YBR0907(orf name)|uniprotkb:YBR111C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11534201|imex:IM-24995-1241	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001157.1|refseq:NP_001243095.1|refseq:NP_001243092.1|dip:DIP-33485N|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0045471"(response to ethanol)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051087"(chaperone binding)|go:"GO:0051591"(response to cAMP)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060544"(regulation of necroptotic process)|go:"GO:0060546"(negative regulation of necroptotic process)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070266"(necroptotic process)|go:"GO:0070424"(regulation of nucleotide-binding oligomerization domain containing signaling pathway)|go:"GO:0098770"(FBXO family protein binding)|go:"GO:1901222"(regulation of NIK/NF-kappaB signaling)|go:"GO:1902443"(negative regulation of ripoptosome assembly involved in necroptotic process)|go:"GO:1902523"(positive regulation of protein K63-linked ubiquitination)|go:"GO:1902524"(positive regulation of protein K48-linked ubiquitination)|go:"GO:1902527"(positive regulation of protein monoubiquitination)|go:"GO:2000116"(regulation of cysteine-type endopeptidase activity)|go:"GO:2000377"(regulation of reactive oxygen species metabolic process)|interpro:IPR001315(Caspase Recruitment)|interpro:IPR001370(Proteinase inhibitor I32, inhibitor of apoptosis)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011029(DEATH-like)|interpro:IPR041933|mint:Q13490|rcsb pdb:1QBH|rcsb pdb:2L9M|rcsb pdb:3D9T|rcsb pdb:3D9U|rcsb pdb:3M1D|rcsb pdb:3MUP|rcsb pdb:3OZ1|rcsb pdb:3T6P|rcsb pdb:3UW4|rcsb pdb:4EB9|rcsb pdb:4HY4|rcsb pdb:4HY5|rcsb pdb:4KMN|rcsb pdb:4LGE|rcsb pdb:4LGU|rcsb pdb:4MTI|rcsb pdb:4MU7|rcsb pdb:5M6N|rcsb pdb:6EXW|rcsb pdb:6HPR|rcsb pdb:6W74|rcsb pdb:6W7O|rcsb pdb:6W8I|reactome:R-HSA-111465|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-5213460|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5668541|reactome:R-HSA-5675482|reactome:R-HSA-5676594|reactome:R-HSA-5689880|reactome:R-HSA-937041|ensembl:ENSG00000110330(gene)|ensembl:ENST00000227758(transcript)|ensembl:ENST00000613397(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001741"(XY body)|go:"GO:0001890"(placenta development)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0016740"(transferase activity)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034121"(regulation of toll-like receptor signaling pathway)|go:"GO:0035631"(CD40 receptor complex)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0039535"(regulation of RIG-I signaling pathway)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|entrezgene/locuslink:329(identity)	refseq:NP_009669.1|sgd:S000000315|interpro:IPR020084|interpro:IPR000086(NUDIX hydrolase, core)|interpro:IPR015797(NUDIX)|reactome:R-SCE-2393930|ensemblfungi:YBR111C(gene)|ensemblfungi:YBR111C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006753"(nucleoside phosphate metabolic process)|go:"GO:0019693"(ribose phosphate metabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0047631"(ADP-ribose diphosphatase activity)|sgd:YBR111C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:FOikzyDyDtlv2l69i/WNDNq674A9606	rogid:tpdVT9ttt/pL+UevSr0zW+rfyIc559292	intact-crc:25278977F5C43EBA|rigid:vhDiILxBzyjxGTbwEavei/yZJ00	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8IYA8	uniprotkb:Q02647	intact:EBI-8638439|intact:EBI-28969497|ensembl:ENSP00000296449|ensembl:ENSP00000391788|ensembl:ENSP00000407837|uniprotkb:C9JJL0|uniprotkb:Q96LP7|intact:MINT-8162095|uniprotkb:Q05DG9	intact:EBI-6240|uniprotkb:D6VT54|ensemblfungi:YDR424C	psi-mi:iho1_human(display_long)|uniprotkb:IHO1(gene name)|psi-mi:IHO1(display_short)|uniprotkb:CCDC36(gene name synonym)|uniprotkb:Cancer/testis antigen 74(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 36(gene name synonym)	psi-mi:dyl1_yeast(display_long)|uniprotkb:DYN2(gene name)|psi-mi:DYN2(display_short)|uniprotkb:SLC1(gene name synonym)|uniprotkb:YDR424C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11534278|imex:IM-24995-1249	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000296449|ensembl:ENST00000366429|ensembl:ENSP00000403700|ensembl:ENSP00000391788|ensembl:ENSP00000407837|ensembl:ENSG00000173421(gene)|ensembl:ENST00000296449(transcript)|ensembl:ENST00000438782(transcript)|ensembl:ENST00000452691(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0006310"(DNA recombination)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0042138"(meiotic DNA double-strand break formation)|go:"GO:0048477"(oogenesis)|go:"GO:0060629"(regulation of homologous chromosome segregation)|interpro:IPR031529|mint:Q8IYA8|refseq:XP_011531974.1|refseq:XP_011531975.1|refseq:NP_001128669.1|refseq:NP_835467.2|refseq:XP_006713187.1|entrezgene/locuslink:339834(identity)	refseq:NP_010712.1|sgd:S000002832|dip:DIP-6480N|mint:Q02647|interpro:IPR001372(Dynein light chain, type 1 and 2)|interpro:IPR019763|interpro:IPR037177|rcsb pdb:4DS1|rcsb pdb:4HT6|reactome:R-SCE-6798695|ensemblfungi:YDR424C(gene)|ensemblfungi:YDR424C_mRNA(transcript)|go:"GO:0005643"(nuclear pore)|go:"GO:0005868"(cytoplasmic dynein complex)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0015031"(protein transport)|go:"GO:0030286"(dynein complex)|go:"GO:0030473"(nuclear migration along microtubule)|go:"GO:0034399"(nuclear periphery)|go:"GO:0040001"(establishment of mitotic spindle localization)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0051028"(mRNA transport)|go:"GO:0051292"(nuclear pore complex assembly)|go:"GO:0051959"(dynein light intermediate chain binding)|go:"GO:1990429"(peroxisomal importomer complex)|go:"GO:2000582"(obsolete positive regulation of microtubule motor activity, plus-end-directed)|sgd:YDR424C(identity)	-	comment:mint	crc64:C25A690F35C3CEEC	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:+TNQLExkhmC1NWqsE240Cx7zFVU9606	rogid:VzzUwItKMyp/zI7n/iI7VK4QiEA559292	intact-crc:A92A267541B8670F|rigid:gohT56T3Co0JinL5kHIziH3vKxc	false	sufficient binding region:11-594	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q02647	uniprotkb:O96015	intact:EBI-6240|uniprotkb:D6VT54|ensemblfungi:YDR424C	intact:EBI-742362|uniprotkb:Q6FGB2|uniprotkb:Q6FGD0|ensembl:ENSP00000216068	psi-mi:dyl1_yeast(display_long)|uniprotkb:DYN2(gene name)|psi-mi:DYN2(display_short)|uniprotkb:SLC1(gene name synonym)|uniprotkb:YDR424C(locus name)	psi-mi:dnal4_human(display_long)|uniprotkb:DNAL4(gene name)|psi-mi:DNAL4(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11534269|imex:IM-24995-1248	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010712.1|sgd:S000002832|dip:DIP-6480N|mint:Q02647|interpro:IPR001372(Dynein light chain, type 1 and 2)|interpro:IPR019763|interpro:IPR037177|rcsb pdb:4DS1|rcsb pdb:4HT6|reactome:R-SCE-6798695|ensemblfungi:YDR424C(gene)|ensemblfungi:YDR424C_mRNA(transcript)|go:"GO:0005643"(nuclear pore)|go:"GO:0005868"(cytoplasmic dynein complex)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0015031"(protein transport)|go:"GO:0030286"(dynein complex)|go:"GO:0030473"(nuclear migration along microtubule)|go:"GO:0034399"(nuclear periphery)|go:"GO:0040001"(establishment of mitotic spindle localization)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0051028"(mRNA transport)|go:"GO:0051292"(nuclear pore complex assembly)|go:"GO:0051959"(dynein light intermediate chain binding)|go:"GO:1990429"(peroxisomal importomer complex)|go:"GO:2000582"(obsolete positive regulation of microtubule motor activity, plus-end-directed)|sgd:YDR424C(identity)	refseq:NP_005731.1|ensembl:ENSG00000100246(gene)|ensembl:ENST00000216068(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0030286"(dynein complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0051959"(dynein light intermediate chain binding)|go:"GO:2000582"(obsolete positive regulation of microtubule motor activity, plus-end-directed)|interpro:IPR001372(Dynein light chain, type 1 and 2)|interpro:IPR037177|mint:O96015|reactome:R-HSA-177504|go:"GO:0003777"(microtubule motor activity)|entrezgene/locuslink:10126(identity)	-	crc64:C25A690F35C3CEEC	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:VzzUwItKMyp/zI7n/iI7VK4QiEA559292	rogid:VT8OXlxBh2Jy6Bb4vMkrAY9M6AA9606	intact-crc:88F0065412ECF2EC|rigid:eccgkpyu1hz19GLGuUcA3KLr8xU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q02642	uniprotkb:P55347	intact:EBI-6371|uniprotkb:Q02107|uniprotkb:D6W3X7|ensemblfungi:YPL037C	intact:EBI-1373569|uniprotkb:O00528|uniprotkb:Q8IWT7|ensembl:ENSP00000291547	psi-mi:nacb1_yeast(display_long)|uniprotkb:EGD1(gene name)|psi-mi:EGD1(display_short)|uniprotkb:Beta-1-NAC(gene name synonym)|uniprotkb:GAL4 DNA-binding enhancer protein 1(gene name synonym)|uniprotkb:BTF3 homolog EGD1(gene name synonym)|uniprotkb:YPL037C(locus name)	psi-mi:pknx1_human(display_long)|uniprotkb:PBX/knotted homeobox 1(gene name synonym)|uniprotkb:Homeobox protein PREP-1(gene name synonym)|uniprotkb:PKNOX1(gene name)|psi-mi:PKNOX1(display_short)|uniprotkb:PREP1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11534260|imex:IM-24995-1247	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015288.1|sgd:S000005958|mint:Q02642|dip:DIP-6561N|ensemblfungi:YPL037C(gene)|ensemblfungi:YPL037C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005854"(nascent polypeptide-associated complex)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR002715(Nascent polypeptide-associated complex NAC)|interpro:IPR038187|interpro:IPR039370|sgd:YPL037C(identity)	refseq:NP_004562.2|ensembl:ENSG00000160199(gene)|ensembl:ENST00000291547(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0030217"(T cell differentiation)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0043010"(camera-type eye development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR008422(Coprinus cinereus mating-type protein)|interpro:IPR009057(Homeodomain-like)|interpro:IPR032453|rcsb pdb:1X2N|reactome:R-HSA-5617472|entrezgene/locuslink:5316(identity)	-	crc64:7C278A3DC79BF95B	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Lrun0emRynb8tO3ViEF/fkUI9SQ559292	rogid:Lg1nUBFHfBFWvGVk9elIXobm5BA9606	intact-crc:CD4FAEB8DDDDD7AB|rigid:bfalhloM1t44nFIvMTfX3o8/9XE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q02642	uniprotkb:P50222	intact:EBI-6371|uniprotkb:Q02107|uniprotkb:D6W3X7|ensemblfungi:YPL037C	intact:EBI-748397|uniprotkb:O75263|ensembl:ENSP00000262041|uniprotkb:Q9UPL6|uniprotkb:B2R8I7|intact:EBI-10172134|intact:EBI-11522964|intact:EBI-11750003|intact:EBI-12702266|uniprotkb:A4D127	psi-mi:nacb1_yeast(display_long)|uniprotkb:EGD1(gene name)|psi-mi:EGD1(display_short)|uniprotkb:Beta-1-NAC(gene name synonym)|uniprotkb:GAL4 DNA-binding enhancer protein 1(gene name synonym)|uniprotkb:BTF3 homolog EGD1(gene name synonym)|uniprotkb:YPL037C(locus name)	psi-mi:meox2_human(display_long)|uniprotkb:Mesenchyme homeobox 2(gene name synonym)|uniprotkb:Growth arrest-specific homeobox(gene name synonym)|uniprotkb:MEOX2(gene name)|psi-mi:MEOX2(display_short)|uniprotkb:GAX(gene name synonym)|uniprotkb:MOX2(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11534251|imex:IM-24995-1246	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015288.1|sgd:S000005958|mint:Q02642|dip:DIP-6561N|ensemblfungi:YPL037C(gene)|ensemblfungi:YPL037C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005854"(nascent polypeptide-associated complex)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR002715(Nascent polypeptide-associated complex NAC)|interpro:IPR038187|interpro:IPR039370|sgd:YPL037C(identity)	ensembl:ENSG00000106511(gene)|ensembl:ENST00000262041(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0001757"(somite specification)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007275"(multicellular organism development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008015"(blood circulation)|go:"GO:0016607"(nuclear speck)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060173"(limb development)|go:"GO:0061053"(somite development)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR042634|refseq:NP_005915.2|entrezgene/locuslink:4223(identity)	-	crc64:7C278A3DC79BF95B	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2017/05/26	rogid:Lrun0emRynb8tO3ViEF/fkUI9SQ559292	rogid:fMv0ruKikzQ3MC0PBvJ3pOAjW+U9606	intact-crc:C4B01B368EC633A0|rigid:n/w0hlOZmoo3PjnN4OQurGwqP9o	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q02724	uniprotkb:Q96DZ9-2	intact:EBI-20050|uniprotkb:D6W3Z2|ensemblfungi:YPL020C	intact:EBI-11522780|ensembl:ENSP00000352270|ensembl:ENSP00000497215	psi-mi:ulp1_yeast(display_long)|uniprotkb:ULP1(gene name)|psi-mi:ULP1(display_short)|uniprotkb:LPB11C(orf name)|uniprotkb:YPL020C(locus name)	psi-mi:q96dz9-2(display_long)|uniprotkb:CMTM5(gene name)|psi-mi:CMTM5(display_short)|uniprotkb:CKLFSF5(gene name synonym)|uniprotkb:Chemokine-like factor superfamily member 5(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11534325|imex:IM-24995-1254	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015305.1|sgd:S000005941|ensemblfungi:YPL020C(gene)|ensemblfungi:YPL020C_mRNA(transcript)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005730"(nucleolus)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0016926"(protein desumoylation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070140"(SUMO-specific isopeptidase activity)|interpro:IPR003653(Peptidase C48, SUMO/Sentrin/Ubl1)|interpro:IPR038765|rcsb pdb:1EUV|rcsb pdb:2HKP|rcsb pdb:2HL8|rcsb pdb:2HL9|rcsb pdb:5H2V|rcsb pdb:5H2W|rcsb pdb:5H2X|reactome:R-SCE-3065679|reactome:R-SCE-6791226|dip:DIP-4041N|mint:Q02724|sgd:YPL020C(identity)	ensembl:ENSG00000166091(gene)|ensembl:ENST00000359320(transcript)|ensembl:ENST00000649278(transcript)|intact:EBI-2548702(isoform-parent)|uniprotkb:Q96DZ9-2(isoform-parent)|entrezgene/locuslink:116173(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:H9B4qZf/ZMbHr7u4hbtR4fzz0ec559292	rogid:2TJ7rZKQNb5hH5gz9i+ujOEOIOg9606	intact-crc:009F54F402F656AB|rigid:bA9ChALF2ya3z9shfdEU0Vaxy9Q	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q02724	uniprotkb:Q8NHQ1	intact:EBI-20050|uniprotkb:D6W3Z2|ensemblfungi:YPL020C	intact:EBI-739624|ensembl:ENSP00000264982|ensembl:ENSP00000419231|uniprotkb:Q96B31|uniprotkb:Q9H2C3|uniprotkb:Q9H2Z1|uniprotkb:Q9H940|uniprotkb:D3DNE9|uniprotkb:B7Z5I8|uniprotkb:B7Z7E8|uniprotkb:F5GZX8	psi-mi:ulp1_yeast(display_long)|uniprotkb:ULP1(gene name)|psi-mi:ULP1(display_short)|uniprotkb:LPB11C(orf name)|uniprotkb:YPL020C(locus name)	psi-mi:cep70_human(display_long)|uniprotkb:CEP70(gene name)|psi-mi:CEP70(display_short)|uniprotkb:BITE(gene name synonym)|uniprotkb:p10-binding protein(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11534316|imex:IM-24995-1253	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015305.1|sgd:S000005941|ensemblfungi:YPL020C(gene)|ensemblfungi:YPL020C_mRNA(transcript)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005730"(nucleolus)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0016926"(protein desumoylation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070140"(SUMO-specific isopeptidase activity)|interpro:IPR003653(Peptidase C48, SUMO/Sentrin/Ubl1)|interpro:IPR038765|rcsb pdb:1EUV|rcsb pdb:2HKP|rcsb pdb:2HL8|rcsb pdb:2HL9|rcsb pdb:5H2V|rcsb pdb:5H2W|rcsb pdb:5H2X|reactome:R-SCE-3065679|reactome:R-SCE-6791226|dip:DIP-4041N|mint:Q02724|sgd:YPL020C(identity)	ensembl:ENSG00000114107(gene)|ensembl:ENST00000264982(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|interpro:IPR019734|interpro:IPR037692|mint:Q8NHQ1|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|ensembl:ENST00000484888(transcript)|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_077817.2|refseq:XP_016862764.1|refseq:NP_001275893.1|refseq:NP_001275894.1|refseq:NP_001275895.1|refseq:NP_001275896.1|refseq:NP_001307527.1|refseq:NP_001307529.1|entrezgene/locuslink:80321(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:H9B4qZf/ZMbHr7u4hbtR4fzz0ec559292	rogid:S4yveQWcvdVtAUX65gqrJ5Dv0Mc9606	intact-crc:7983CA362D4E8BBE|rigid:f93dJ2zT3oTwvFJuKkqvhFFZJkU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8N6L0	uniprotkb:Q02724	intact:EBI-749265|uniprotkb:Q96MC3|ensembl:ENSP00000404220	intact:EBI-20050|uniprotkb:D6W3Z2|ensemblfungi:YPL020C	psi-mi:kash5_human(display_long)|uniprotkb:KASH5(gene name)|psi-mi:KASH5(display_short)|uniprotkb:CCDC155(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 155(gene name synonym)|uniprotkb:KASH domain-containing protein 5(gene name synonym)	psi-mi:ulp1_yeast(display_long)|uniprotkb:ULP1(gene name)|psi-mi:ULP1(display_short)|uniprotkb:LPB11C(orf name)|uniprotkb:YPL020C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11534307|imex:IM-24995-1252	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_653289.3|ensembl:ENSG00000161609(gene)|ensembl:ENST00000447857(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034397"(telomere localization)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051225"(spindle assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0090172"(microtubule cytoskeleton organization involved in homologous chromosome segregation)|go:"GO:0090220"(chromosome localization to nuclear envelope involved in homologous chromosome segregation)|go:"GO:0090619"(meiotic spindle pole)|interpro:IPR011992(EF-Hand type)|interpro:IPR028168|interpro:IPR028170|interpro:IPR039508|mint:Q8N6L0|rcsb pdb:6R2I|rcsb pdb:6WMF|entrezgene/locuslink:147872(identity)	refseq:NP_015305.1|sgd:S000005941|ensemblfungi:YPL020C(gene)|ensemblfungi:YPL020C_mRNA(transcript)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005730"(nucleolus)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0016926"(protein desumoylation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070140"(SUMO-specific isopeptidase activity)|interpro:IPR003653(Peptidase C48, SUMO/Sentrin/Ubl1)|interpro:IPR038765|rcsb pdb:1EUV|rcsb pdb:2HKP|rcsb pdb:2HL8|rcsb pdb:2HL9|rcsb pdb:5H2V|rcsb pdb:5H2W|rcsb pdb:5H2X|reactome:R-SCE-3065679|reactome:R-SCE-6791226|dip:DIP-4041N|mint:Q02724|sgd:YPL020C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Wl9L7AcvDHCZuKjYLn8QgGIbZTc9606	rogid:H9B4qZf/ZMbHr7u4hbtR4fzz0ec559292	intact-crc:756E08B5F656293B|rigid:kcJcZoruEPpVCr09h4BbpwgBs2s	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q02724	uniprotkb:Q6RW13-2	intact:EBI-20050|uniprotkb:D6W3Z2|ensemblfungi:YPL020C	intact:EBI-11522760|ensembl:ENSP00000365816	psi-mi:ulp1_yeast(display_long)|uniprotkb:ULP1(gene name)|psi-mi:ULP1(display_short)|uniprotkb:LPB11C(orf name)|uniprotkb:YPL020C(locus name)	psi-mi:q6rw13-2(display_long)|uniprotkb:AGTRAP(gene name)|psi-mi:AGTRAP(display_short)|uniprotkb:AT1 receptor-associated protein(gene name synonym)|uniprotkb:ATRAP(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11534298|imex:IM-24995-1251	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015305.1|sgd:S000005941|ensemblfungi:YPL020C(gene)|ensemblfungi:YPL020C_mRNA(transcript)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005730"(nucleolus)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0016926"(protein desumoylation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070140"(SUMO-specific isopeptidase activity)|interpro:IPR003653(Peptidase C48, SUMO/Sentrin/Ubl1)|interpro:IPR038765|rcsb pdb:1EUV|rcsb pdb:2HKP|rcsb pdb:2HL8|rcsb pdb:2HL9|rcsb pdb:5H2V|rcsb pdb:5H2W|rcsb pdb:5H2X|reactome:R-SCE-3065679|reactome:R-SCE-6791226|dip:DIP-4041N|mint:Q02724|sgd:YPL020C(identity)	ensembl:ENSG00000177674(gene)|ensembl:ENST00000376629(transcript)|intact:EBI-741181(isoform-parent)|uniprotkb:Q6RW13-2(isoform-parent)|entrezgene/locuslink:57085(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:H9B4qZf/ZMbHr7u4hbtR4fzz0ec559292	rogid:PNzVis/8puQZBJ562gCqZKc078s9606	intact-crc:9B8DC18CA04C9D91|rigid:71n37RR9MkaYxPdD0E2912OYv14	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q02724	uniprotkb:Q15041	intact:EBI-20050|uniprotkb:D6W3Z2|ensemblfungi:YPL020C	intact:EBI-714543|ensembl:ENSP00000306788|uniprotkb:B7Z6S5|uniprotkb:B7Z791|uniprotkb:F5GXP4	psi-mi:ulp1_yeast(display_long)|uniprotkb:ULP1(gene name)|psi-mi:ULP1(display_short)|uniprotkb:LPB11C(orf name)|uniprotkb:YPL020C(locus name)	psi-mi:ar6p1_human(display_long)|uniprotkb:ARL6IP(gene name synonym)|uniprotkb:ARL6IP1(gene name)|psi-mi:ARL6IP1(display_short)|uniprotkb:KIAA0069(gene name synonym)|uniprotkb:ARMER(gene name synonym)|uniprotkb:Apoptotic regulator in the membrane of the endoplasmic reticulum(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11534289|imex:IM-24995-1250	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015305.1|sgd:S000005941|ensemblfungi:YPL020C(gene)|ensemblfungi:YPL020C_mRNA(transcript)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005730"(nucleolus)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0016926"(protein desumoylation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070140"(SUMO-specific isopeptidase activity)|interpro:IPR003653(Peptidase C48, SUMO/Sentrin/Ubl1)|interpro:IPR038765|rcsb pdb:1EUV|rcsb pdb:2HKP|rcsb pdb:2HL8|rcsb pdb:2HL9|rcsb pdb:5H2V|rcsb pdb:5H2W|rcsb pdb:5H2X|reactome:R-SCE-3065679|reactome:R-SCE-6791226|dip:DIP-4041N|mint:Q02724|sgd:YPL020C(identity)	refseq:NP_055976.1|ensembl:ENSG00000170540(gene)|ensembl:ENST00000304414(transcript)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006613"(cotranslational protein targeting to membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0071787"(endoplasmic reticulum tubular network formation)|go:"GO:1903371"(regulation of endoplasmic reticulum tubular network organization)|go:"GO:1990809"(endoplasmic reticulum tubular network membrane organization)|interpro:IPR033301|mint:Q15041|go:"GO:0002038"(positive regulation of L-glutamate import across plasma membrane)|refseq:NP_001300787.1|entrezgene/locuslink:23204(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:H9B4qZf/ZMbHr7u4hbtR4fzz0ec559292	rogid:3fjkoyvUx25po7xsPcXgpjEeLJg9606	intact-crc:0390FFCEFDE31EC2|rigid:RIbaQ21M7h0vj230QEBaFTZm9ok	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q02793	uniprotkb:Q5D1E8	intact:EBI-17260|uniprotkb:D6VTU2|ensemblfungi:YGL213C	intact:EBI-747793|uniprotkb:Q6I9Z1|uniprotkb:Q9H5P1|uniprotkb:D3DPT0|ensembl:ENSP00000362179	psi-mi:ski8_yeast(display_long)|uniprotkb:YGL213C(locus name)|uniprotkb:SKI8(gene name)|psi-mi:SKI8(display_short)|uniprotkb:REC103(gene name synonym)|uniprotkb:Superkiller protein 8(gene name synonym)	psi-mi:zc12a_human(display_long)|uniprotkb:MCPIP(gene name synonym)|uniprotkb:MCPIP1(gene name synonym)|uniprotkb:ZC3H12A(gene name)|psi-mi:ZC3H12A(display_short)|uniprotkb:Monocyte chemotactic protein-induced protein 1(gene name synonym)|uniprotkb:Regnase-1(gene name synonym)|uniprotkb:Zinc finger CCCH domain-containing protein 12A(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11534370|imex:IM-24995-1259	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011302.1|sgd:S000003181|ensemblfungi:YGL213C(gene)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034622"|go:"GO:0051607"(defense response to virus)|go:"GO:0055087"(Ski complex)|go:"GO:0065004"(protein-DNA complex assembly)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|rcsb pdb:1S4U|rcsb pdb:1SQ9|rcsb pdb:4BUJ|rcsb pdb:5MC6|reactome:R-SCE-429958|reactome:R-SCE-674695|reactome:R-SCE-75955|ensemblfungi:YGL213C_mRNA(transcript)|dip:DIP-1653N|mint:Q02793|sgd:YGL213C(identity)	refseq:NP_079355.2|refseq:NP_001310479.1|ensembl:ENSG00000163874(gene)|ensembl:ENST00000373087(transcript)|go:"GO:0000294"(nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay)|go:"GO:0000932"(P-body)|go:"GO:0001525"(angiogenesis)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0002757"(immune response-activating signal transduction)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0004532"(exoribonuclease activity)|go:"GO:0004540"(ribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007399"(nervous system development)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010656"(negative regulation of muscle cell apoptotic process)|go:"GO:0010884"(positive regulation of lipid storage)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0030154"(cell differentiation)|go:"GO:0030867"(rough endoplasmic reticulum membrane)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032691"(negative regulation of interleukin-1 beta production)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035198"(miRNA binding)|go:"GO:0035613"(RNA stem-loop binding)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042406"(extrinsic component of endoplasmic reticulum membrane)|go:"GO:0043022"(ribosome binding)|go:"GO:0043031"(negative regulation of macrophage activation)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0044828"(negative regulation by host of viral genome replication)|go:"GO:0045019"(negative regulation of nitric oxide biosynthetic process)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051607"(defense response to virus)|go:"GO:0055118"(negative regulation of cardiac muscle contraction)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0090501"(RNA phosphodiester bond hydrolysis)|go:"GO:0090502"(RNA phosphodiester bond hydrolysis, endonucleolytic)|go:"GO:0098586"(cellular response to virus)|go:"GO:1900016"(negative regulation of cytokine production involved in inflammatory response)|go:"GO:1900119"(positive regulation of execution phase of apoptosis)|go:"GO:1901223"(negative regulation of NIK/NF-kappaB signaling)|go:"GO:1903003"(positive regulation of protein deubiquitination)|go:"GO:1903799"(negative regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1903936"(cellular response to sodium arsenite)|go:"GO:1904637"(cellular response to ionomycin)|go:"GO:1990869"(cellular response to chemokine)|go:"GO:2000320"(negative regulation of T-helper 17 cell differentiation)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|go:"GO:2000627"(positive regulation of miRNA catabolic process)|interpro:IPR021869|interpro:IPR040546|interpro:IPR040757|rcsb pdb:3V32|rcsb pdb:3V33|rcsb pdb:3V34|go:"GO:1900745"(positive regulation of p38MAPK cascade)|entrezgene/locuslink:80149(identity)	-	crc64:C5E7B9D2268F9727	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:6K6FJYcctdlT1321Nv6pOnQPwq8559292	rogid:3FqqH/XrYjHaa5oJpPXvfYwHKCQ9606	intact-crc:EC50FF3798B08CC3|rigid:BYi2vr6auPKAMD8M263RLfI4o+4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q02793	uniprotkb:P38432	intact:EBI-17260|uniprotkb:D6VTU2|ensemblfungi:YGL213C	intact:EBI-945751|uniprotkb:B2R931|ensembl:ENSP00000240316	psi-mi:ski8_yeast(display_long)|uniprotkb:YGL213C(locus name)|uniprotkb:SKI8(gene name)|psi-mi:SKI8(display_short)|uniprotkb:REC103(gene name synonym)|uniprotkb:Superkiller protein 8(gene name synonym)	psi-mi:coil_human(display_long)|uniprotkb:COIL(gene name)|psi-mi:COIL(display_short)|uniprotkb:CLN80(gene name synonym)|uniprotkb:p80-coilin(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11534361|imex:IM-24995-1258	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011302.1|sgd:S000003181|ensemblfungi:YGL213C(gene)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034622"|go:"GO:0051607"(defense response to virus)|go:"GO:0055087"(Ski complex)|go:"GO:0065004"(protein-DNA complex assembly)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|rcsb pdb:1S4U|rcsb pdb:1SQ9|rcsb pdb:4BUJ|rcsb pdb:5MC6|reactome:R-SCE-429958|reactome:R-SCE-674695|reactome:R-SCE-75955|ensemblfungi:YGL213C_mRNA(transcript)|dip:DIP-1653N|mint:Q02793|sgd:YGL213C(identity)	refseq:NP_004636.1|dip:DIP-38503N|ensembl:ENSG00000121058(gene)|ensembl:ENST00000240316(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0015030"(Cajal body)|go:"GO:0016020"(membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0030619"(U1 snRNA binding)|go:"GO:0030620"(U2 snRNA binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR024822|interpro:IPR031722|mint:P38432|entrezgene/locuslink:8161(identity)	-	crc64:C5E7B9D2268F9727	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:6K6FJYcctdlT1321Nv6pOnQPwq8559292	rogid:hd5p6AbyA/GYNEeca99Mdb41qM09606	intact-crc:E9E9B1AD8BE24888|rigid:ABp9irOa3eI3gW27e08nrIbXS78	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q02793	uniprotkb:O00444	intact:EBI-17260|uniprotkb:D6VTU2|ensemblfungi:YGL213C	intact:EBI-746202|uniprotkb:Q8IYF0|uniprotkb:Q96Q95|uniprotkb:B2RAL0|uniprotkb:B7Z837|uniprotkb:B7Z8G7|uniprotkb:Q9UD84|uniprotkb:Q9UDE2|ensembl:ENSP00000270861	psi-mi:ski8_yeast(display_long)|uniprotkb:YGL213C(locus name)|uniprotkb:SKI8(gene name)|psi-mi:SKI8(display_short)|uniprotkb:REC103(gene name synonym)|uniprotkb:Superkiller protein 8(gene name synonym)	psi-mi:plk4_human(display_long)|uniprotkb:Polo-like kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase Sak(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 18(gene name synonym)|uniprotkb:PLK4(gene name)|psi-mi:PLK4(display_short)|uniprotkb:SAK(gene name synonym)|uniprotkb:STK18(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11534352|imex:IM-24995-1257	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011302.1|sgd:S000003181|ensemblfungi:YGL213C(gene)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034622"|go:"GO:0051607"(defense response to virus)|go:"GO:0055087"(Ski complex)|go:"GO:0065004"(protein-DNA complex assembly)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|rcsb pdb:1S4U|rcsb pdb:1SQ9|rcsb pdb:4BUJ|rcsb pdb:5MC6|reactome:R-SCE-429958|reactome:R-SCE-674695|reactome:R-SCE-75955|ensemblfungi:YGL213C_mRNA(transcript)|dip:DIP-1653N|mint:Q02793|sgd:YGL213C(identity)	refseq:NP_001177728.1|refseq:NP_001177730.1|refseq:NP_055079.3|dip:DIP-34467N|rcsb pdb:5LHZ|rcsb pdb:6N45|rcsb pdb:6N46|rcsb pdb:6W38|rcsb pdb:6W3I|rcsb pdb:6W3J|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|rcsb pdb:5LHY|reactome:R-HSA-5620912|reactome:R-HSA-8854518|ensembl:ENSG00000142731(gene)|ensembl:ENST00000270861(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0001741"(XY body)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007099"(centriole replication)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0046601"(positive regulation of centriole replication)|go:"GO:0060271"(cilium assembly)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0098535"(de novo centriole assembly involved in multi-ciliated epithelial cell differentiation)|go:"GO:0098536"(deuterosome)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033696|interpro:IPR033698|interpro:IPR033699|interpro:IPR033700|mint:O00444|rcsb pdb:2N19|rcsb pdb:3COK|rcsb pdb:4JXF|rcsb pdb:4N7V|rcsb pdb:4N7Z|rcsb pdb:4N9J|rcsb pdb:4YUR|rcsb pdb:4YYP|entrezgene/locuslink:10733(identity)	-	crc64:C5E7B9D2268F9727	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:6K6FJYcctdlT1321Nv6pOnQPwq8559292	rogid:xqjVEnoGXDk/+2AzLRAkyPK80OI9606	intact-crc:5889ADDBB1E394E4|rigid:b94IcmKAtMw/tw+81P5wYoO+MTk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96BA8	uniprotkb:Q02774	intact:EBI-6942903|ensembl:ENSP00000481956|intact:MINT-268046|intact:MINT-8162577|uniprotkb:Q8N2D5|uniprotkb:Q96CP0	intact:EBI-17099|uniprotkb:Q12413|ensemblfungi:YDL212W|uniprotkb:D6VRE2	psi-mi:cr3l1_human(display_long)|uniprotkb:CREB3L1(gene name)|psi-mi:CREB3L1(display_short)|uniprotkb:OASIS(gene name synonym)|uniprotkb:PSEC0238(orf name)|uniprotkb:Old astrocyte specifically-induced substance(gene name synonym)	psi-mi:shr3_yeast(display_long)|uniprotkb:D1022(orf name)|uniprotkb:YDL212W(locus name)|uniprotkb:SHR3(gene name)|psi-mi:SHR3(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11534343|imex:IM-24995-1256	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157613(gene)|ensembl:ENST00000621158(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0070278"(extracellular matrix constituent secretion)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029805|mint:Q96BA8|reactome:R-HSA-8874211|refseq:NP_443086.1|entrezgene/locuslink:90993(identity)	refseq:NP_010069.1|sgd:S000002371|ensemblfungi:YDL212W(gene)|ensemblfungi:YDL212W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006457"(protein folding)|go:"GO:0006865"(amino acid transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0015031"(protein transport)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0043332"(mating projection tip)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0090114"(COPII-coated vesicle budding)|interpro:IPR013248(Shr3 amino acid permease chaperone)|dip:DIP-1615N|mint:Q02774|sgd:YDL212W(identity)	-	comment:mint|function:"Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE"	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:sMWUFmBeBBCO+T0Y2CuB/un1lBg9606	rogid:IGYbkr6cAVoYYx9LhZxB/B9Onnc559292	intact-crc:66B9BA9E47488116|rigid:UDV0bPWPNi4/8lKzGW+XAxfEZNg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UMX0	uniprotkb:Q02771	intact:EBI-741480|uniprotkb:Q8IXS9|uniprotkb:Q8N2Q3|uniprotkb:Q9H0T8|uniprotkb:Q9H3R4|uniprotkb:Q9HAZ5|intact:EBI-28967608|ensembl:ENSP00000365576|uniprotkb:Q5T6J5|uniprotkb:Q5T6J9|uniprotkb:A0A024R284	intact:EBI-14092|ensemblfungi:YER058W|uniprotkb:D3DLW2	psi-mi:ubql1_human(display_long)|uniprotkb:Protein linking IAP with cytoskeleton 1(gene name synonym)|uniprotkb:UBQLN1(gene name)|psi-mi:UBQLN1(display_short)|uniprotkb:DA41(gene name synonym)|uniprotkb:PLIC1(gene name synonym)	psi-mi:pt117_yeast(display_long)|uniprotkb:PET117(gene name)|psi-mi:PET117(display_short)|uniprotkb:YER058W(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11534334|imex:IM-24995-1255	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000257468|ensembl:ENSP00000257468|ensembl:ENSP00000365576|ensembl:ENSG00000135018(gene)|ensembl:ENST00000376395(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000502"(proteasome complex)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016235"(aggresome)|go:"GO:0016236"(macroautophagy)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0019900"(kinase binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035973"(aggrephagy)|go:"GO:0042802"(identical protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0097352"(autophagosome maturation)|go:"GO:1901340"(negative regulation of store-operated calcium channel activity)|go:"GO:1902175"(regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)|interpro:IPR000626(Ubiquitin)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR028430|interpro:IPR029071|mint:Q9UMX0|rcsb pdb:2JY5|rcsb pdb:2JY6|rcsb pdb:2KLC|reactome:R-HSA-8856825|refseq:NP_038466.2|refseq:NP_444295.1|dip:DIP-41629N|entrezgene/locuslink:29979(identity)	sgd:S000000860|refseq:NP_010979.1|ensemblfungi:YER058W(gene)|ensemblfungi:YER058W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0033617"(mitochondrial cytochrome c oxidase assembly)|go:"GO:0099616"(extrinsic component of matrix side of mitochondrial inner membrane)|interpro:IPR031568|dip:DIP-5118N|sgd:YER058W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:nCFfZbGCTvRYaXhQ4R99XblslvM9606	rogid:olrpTXf4PLFKXG++Rcnf3PlDjLM559292	intact-crc:73FFAB923B13993D|rigid:XtkcU8jqAgTu14EfwtOcBwul8ZE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O00635	uniprotkb:Q02821	intact:EBI-2130415|uniprotkb:B2R862|ensembl:ENSP00000349596	intact:EBI-1797|uniprotkb:D6W0Z8|ensemblfungi:YNL189W	psi-mi:tri38_human(display_long)|uniprotkb:TRIM38(gene name)|psi-mi:TRIM38(display_short)|uniprotkb:RNF15(gene name synonym)|uniprotkb:RORET(gene name synonym)|uniprotkb:RING finger protein 15(gene name synonym)|uniprotkb:Zinc finger protein RoRet(gene name synonym)|uniprotkb:Tripartite motif-containing protein 38(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM38(gene name synonym)	psi-mi:ima1_yeast(display_long)|uniprotkb:SRP1(gene name)|psi-mi:SRP1(display_short)|uniprotkb:KAP60(gene name synonym)|uniprotkb:YNL189W(locus name)|uniprotkb:N1606(orf name)|uniprotkb:Karyopherin subunit alpha(gene name synonym)|uniprotkb:Karyopherin-60(gene name synonym)|uniprotkb:Serine-rich RNA polymerase I suppressor protein(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11534408|imex:IM-24995-1263	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006346.1|refseq:XP_005248856.1|refseq:XP_005248857.1|ensembl:ENSG00000112343(gene)|ensembl:ENST00000357085(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046598"(positive regulation of viral entry into host cell)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR035790|interpro:IPR043136|reactome:R-HSA-877300|entrezgene/locuslink:10475(identity)	refseq:NP_014210.1|sgd:S000005133|dip:DIP-728N|mint:Q02821|ensemblfungi:YNL189W(gene)|ensemblfungi:YNL189W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0031144"(proteasome localization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042564"(NLS-dependent protein nuclear import complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|rcsb pdb:1BK5|rcsb pdb:1BK6|rcsb pdb:1EE4|rcsb pdb:1EE5|rcsb pdb:1UN0|rcsb pdb:1WA5|rcsb pdb:2C1T|rcsb pdb:4PVZ|rcsb pdb:4XZR|rcsb pdb:5H2W|rcsb pdb:5H2X|rcsb pdb:5T94|sgd:YNL189W(identity)	-	-	crc64:8D3A0CB76F2E7C00	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Zh4X/6v/qKZlDkMV6hhn7OsvPnQ9606	rogid:NyzC93xnBCb8DX/AH346lwg4u2A559292	intact-crc:D666D326908AA712|rigid:oSEeJqNHyIdmz0zFygbv5rM4TXg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q7Z6G3-2	uniprotkb:Q02821	intact:EBI-10172876|ensembl:ENSP00000457354|intact:EBI-14062040	intact:EBI-1797|uniprotkb:D6W0Z8|ensemblfungi:YNL189W	psi-mi:q7z6g3-2(display_long)|uniprotkb:EFCBP2(gene name synonym)|uniprotkb:Neuronal calcium-binding protein 2(gene name synonym)|uniprotkb:Synaptotagmin-interacting protein 2(gene name synonym)|uniprotkb:NECAB2(gene name)|psi-mi:NECAB2(display_short)	psi-mi:ima1_yeast(display_long)|uniprotkb:SRP1(gene name)|psi-mi:SRP1(display_short)|uniprotkb:KAP60(gene name synonym)|uniprotkb:YNL189W(locus name)|uniprotkb:N1606(orf name)|uniprotkb:Karyopherin subunit alpha(gene name synonym)|uniprotkb:Karyopherin-60(gene name synonym)|uniprotkb:Serine-rich RNA polymerase I suppressor protein(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11534397|imex:IM-24995-1262	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000103154(gene)|ensembl:ENST00000565691(transcript)|uniprotkb:Q7Z6G3-2(isoform-parent)|intact:EBI-950070(isoform-parent)|entrezgene/locuslink:54550(identity)	refseq:NP_014210.1|sgd:S000005133|dip:DIP-728N|mint:Q02821|ensemblfungi:YNL189W(gene)|ensemblfungi:YNL189W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0031144"(proteasome localization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042564"(NLS-dependent protein nuclear import complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|rcsb pdb:1BK5|rcsb pdb:1BK6|rcsb pdb:1EE4|rcsb pdb:1EE5|rcsb pdb:1UN0|rcsb pdb:1WA5|rcsb pdb:2C1T|rcsb pdb:4PVZ|rcsb pdb:4XZR|rcsb pdb:5H2W|rcsb pdb:5H2X|rcsb pdb:5T94|sgd:YNL189W(identity)	-	-	crc64:8D3A0CB76F2E7C00	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:4S7oIx6h+mKzV3EPxqcfMNqaNko9606	rogid:NyzC93xnBCb8DX/AH346lwg4u2A559292	intact-crc:E8BD53B6D646800A|rigid:hrdlqQvsmzhYRpTN4bYczcX5pEA	false	sufficient binding region:65-303	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q02821	uniprotkb:A0A0C4DGF1	intact:EBI-1797|uniprotkb:D6W0Z8|ensemblfungi:YNL189W	intact:EBI-10188476|ensembl:ENSP00000433657	psi-mi:ima1_yeast(display_long)|uniprotkb:SRP1(gene name)|psi-mi:SRP1(display_short)|uniprotkb:KAP60(gene name synonym)|uniprotkb:YNL189W(locus name)|uniprotkb:N1606(orf name)|uniprotkb:Karyopherin subunit alpha(gene name synonym)|uniprotkb:Karyopherin-60(gene name synonym)|uniprotkb:Serine-rich RNA polymerase I suppressor protein(gene name synonym)	psi-mi:a0a0c4dgf1_human(display_long)|uniprotkb:ZBTB32(gene name)|psi-mi:ZBTB32(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11534388|imex:IM-24995-1261	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014210.1|sgd:S000005133|dip:DIP-728N|mint:Q02821|ensemblfungi:YNL189W(gene)|ensemblfungi:YNL189W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0031144"(proteasome localization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042564"(NLS-dependent protein nuclear import complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|rcsb pdb:1BK5|rcsb pdb:1BK6|rcsb pdb:1EE4|rcsb pdb:1EE5|rcsb pdb:1UN0|rcsb pdb:1WA5|rcsb pdb:2C1T|rcsb pdb:4PVZ|rcsb pdb:4XZR|rcsb pdb:5H2W|rcsb pdb:5H2X|rcsb pdb:5T94|sgd:YNL189W(identity)	interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|ensembl:ENSG00000011590(gene)|ensembl:ENST00000481182(transcript)|go:"GO:0042802"(identical protein binding)|entrezgene/locuslink:27033(identity)	-	crc64:8D3A0CB76F2E7C00	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:NyzC93xnBCb8DX/AH346lwg4u2A559292	rogid:w3k7YT4kw/T+Xi5YBqGHSpHtwMM9606	intact-crc:C55FE1A841CAD438|rigid:SJnLFil/JKxND/k7uaUdrRDCNwE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q02821	uniprotkb:Q96A10	intact:EBI-1797|uniprotkb:D6W0Z8|ensemblfungi:YNL189W	intact:EBI-10486892|intact:EBI-11528237|ensembl:ENSP00000488921	psi-mi:ima1_yeast(display_long)|uniprotkb:SRP1(gene name)|psi-mi:SRP1(display_short)|uniprotkb:KAP60(gene name synonym)|uniprotkb:YNL189W(locus name)|uniprotkb:N1606(orf name)|uniprotkb:Karyopherin subunit alpha(gene name synonym)|uniprotkb:Karyopherin-60(gene name synonym)|uniprotkb:Serine-rich RNA polymerase I suppressor protein(gene name synonym)	psi-mi:q96a10_human(display_long)|uniprotkb:ERVK3-1(gene name)|psi-mi:ERVK3-1(display_short)|uniprotkb:hCG_2043597(orf name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11534379|imex:IM-24995-1260	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014210.1|sgd:S000005133|dip:DIP-728N|mint:Q02821|ensemblfungi:YNL189W(gene)|ensemblfungi:YNL189W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0031144"(proteasome localization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042564"(NLS-dependent protein nuclear import complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|rcsb pdb:1BK5|rcsb pdb:1BK6|rcsb pdb:1EE4|rcsb pdb:1EE5|rcsb pdb:1UN0|rcsb pdb:1WA5|rcsb pdb:2C1T|rcsb pdb:4PVZ|rcsb pdb:4XZR|rcsb pdb:5H2W|rcsb pdb:5H2X|rcsb pdb:5T94|sgd:YNL189W(identity)	ensembl:ENSG00000142396(gene)|ensembl:ENST00000427361(transcript)|entrezgene/locuslink:113386(identity)	-	crc64:8D3A0CB76F2E7C00	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/17	rogid:NyzC93xnBCb8DX/AH346lwg4u2A559292	rogid:UGl9ZpnDNz58eECRstJXxM5bj9I9606	intact-crc:F8023018B45706C4|rigid:PfXqrP00JKkZ9DrWN17KbMlKCFg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q02821	uniprotkb:P60709	intact:EBI-1797|uniprotkb:D6W0Z8|ensemblfungi:YNL189W	intact:EBI-353944|uniprotkb:P02570|uniprotkb:P70514|uniprotkb:P99021|uniprotkb:Q11211|uniprotkb:Q64316|uniprotkb:Q75MN2|uniprotkb:Q96B34|uniprotkb:Q96HG5|ensembl:ENSP00000494269|ensembl:ENSP00000494750|ensembl:ENSP00000495995|ensembl:ENSP00000501862|ensembl:ENSP00000502821	psi-mi:ima1_yeast(display_long)|uniprotkb:SRP1(gene name)|psi-mi:SRP1(display_short)|uniprotkb:KAP60(gene name synonym)|uniprotkb:YNL189W(locus name)|uniprotkb:N1606(orf name)|uniprotkb:Karyopherin subunit alpha(gene name synonym)|uniprotkb:Karyopherin-60(gene name synonym)|uniprotkb:Serine-rich RNA polymerase I suppressor protein(gene name synonym)	psi-mi:actb_human(display_long)|uniprotkb:ACTB(gene name)|psi-mi:ACTB(display_short)|uniprotkb:Beta-actin(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11534454|imex:IM-24995-1268	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014210.1|sgd:S000005133|dip:DIP-728N|mint:Q02821|ensemblfungi:YNL189W(gene)|ensemblfungi:YNL189W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0031144"(proteasome localization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042564"(NLS-dependent protein nuclear import complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|rcsb pdb:1BK5|rcsb pdb:1BK6|rcsb pdb:1EE4|rcsb pdb:1EE5|rcsb pdb:1UN0|rcsb pdb:1WA5|rcsb pdb:2C1T|rcsb pdb:4PVZ|rcsb pdb:4XZR|rcsb pdb:5H2W|rcsb pdb:5H2X|rcsb pdb:5T94|sgd:YNL189W(identity)	refseq:NP_001092.1|ensembl:ENSG00000075624(gene)|ensembl:ENST00000493945(transcript)|ensembl:ENST00000642480(transcript)|ensembl:ENST00000646664(transcript)|ensembl:ENST00000674681(transcript)|ensembl:ENST00000675515(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000785"(chromatin)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0001895"(retina homeostasis)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007409"(axonogenesis)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019894"(kinesin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0022898"(regulation of transmembrane transporter activity)|go:"GO:0030027"(lamellipodium)|go:"GO:0030424"(axon)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0030957"(Tat protein binding)|go:"GO:0031982"(vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034333"(adherens junction assembly)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043044"|go:"GO:0043296"(apical junction complex)|go:"GO:0044305"(calyx of Held)|go:"GO:0045176"(apical protein localization)|go:"GO:0045202"(synapse)|go:"GO:0048156"(tau protein binding)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048870"(cell motility)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051621"(regulation of norepinephrine uptake)|go:"GO:0051623"(positive regulation of norepinephrine uptake)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070160"(tight junction)|go:"GO:0070527"(platelet aggregation)|reactome:R-HSA-4420097|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0072562"(blood microparticle)|go:"GO:0072749"(cellular response to cytochalasin B)|go:"GO:0097433"(dense body)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098973"(structural constituent of postsynaptic actin cytoskeleton)|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0150111"(regulation of transepithelial transport)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P60709|rcsb pdb:3BYH|rcsb pdb:3D2U|rcsb pdb:3J82|rcsb pdb:3LUE|rcsb pdb:6ANU|rcsb pdb:6ICT|rcsb pdb:6ICV|rcsb pdb:6LTJ|rcsb pdb:6MBJ|rcsb pdb:6MBK|rcsb pdb:6MBL|rcsb pdb:6NBW|rcsb pdb:6OX0|rcsb pdb:6OX1|rcsb pdb:6OX2|rcsb pdb:6OX3|rcsb pdb:6OX4|rcsb pdb:6OX5|rcsb pdb:6V62|rcsb pdb:6V63|rcsb pdb:6WK1|rcsb pdb:6WK2|rcsb pdb:7AS4|reactome:R-HSA-1445148|reactome:R-HSA-190873|reactome:R-HSA-196025|reactome:R-HSA-2029482|reactome:R-HSA-3214847|reactome:R-HSA-389957|reactome:R-HSA-390450|reactome:R-HSA-3928662|reactome:R-HSA-3928665|reactome:R-HSA-418990|reactome:R-HSA-437239|reactome:R-HSA-446353|reactome:R-HSA-5250924|reactome:R-HSA-5626467|reactome:R-HSA-5663213|reactome:R-HSA-5663220|reactome:R-HSA-5674135|reactome:R-HSA-5689603|reactome:R-HSA-5696394|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8856828|reactome:R-HSA-9035034|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9662360|reactome:R-HSA-9662361|reactome:R-HSA-9664422|reactome:R-HSA-983231|reactome:R-HSA-445095|dip:DIP-29686N|entrezgene/locuslink:60(identity)	-	crc64:8D3A0CB76F2E7C00	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:NyzC93xnBCb8DX/AH346lwg4u2A559292	rogid:Hoge1B8Pn56kvbNTpkSLsQuHwRc9606	intact-crc:6B66E6DFC40C6572|rigid:d5kT30yHU6iENIXi1DeN1T8yljU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P35520	uniprotkb:Q02821	intact:EBI-740135|uniprotkb:Q99425|uniprotkb:Q9BWC5|uniprotkb:B2R993|uniprotkb:D3DSK4|intact:EBI-14245939|ensembl:ENSP00000344460|ensembl:ENSP00000352643|ensembl:ENSP00000381225|ensembl:ENSP00000381231	intact:EBI-1797|uniprotkb:D6W0Z8|ensemblfungi:YNL189W	psi-mi:cbs_human(display_long)|uniprotkb:CBS(gene name)|psi-mi:CBS(display_short)|uniprotkb:Serine sulfhydrase(gene name synonym)|uniprotkb:Beta-thionase(gene name synonym)	psi-mi:ima1_yeast(display_long)|uniprotkb:SRP1(gene name)|psi-mi:SRP1(display_short)|uniprotkb:KAP60(gene name synonym)|uniprotkb:YNL189W(locus name)|uniprotkb:N1606(orf name)|uniprotkb:Karyopherin subunit alpha(gene name synonym)|uniprotkb:Karyopherin-60(gene name synonym)|uniprotkb:Serine-rich RNA polymerase I suppressor protein(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11534444|imex:IM-24995-1267	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000062.1|refseq:NP_001171479.1|refseq:NP_001171480.1|ensembl:ENSG00000160200(gene)|ensembl:ENST00000352178(transcript)|ensembl:ENST00000359624(transcript)|ensembl:ENST00000398158(transcript)|go:"GO:0004122"(cystathionine beta-synthase activity)|ensembl:ENST00000398165(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006535"(cysteine biosynthetic process from serine)|go:"GO:0006563"(L-serine metabolic process)|go:"GO:0006565"(L-serine catabolic process)|go:"GO:0019343"(cysteine biosynthetic process via cystathionine)|go:"GO:0019344"(cysteine biosynthetic process)|go:"GO:0019346"(transsulfuration)|go:"GO:0019448"(L-cysteine catabolic process)|go:"GO:0019825"(oxygen binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0020037"(heme binding)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042262"(DNA protection)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043418"(homocysteine catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0050421"("nitrite reductase (NO-forming) activity")|go:"GO:0050667"(homocysteine metabolic process)|go:"GO:0070025"(carbon monoxide binding)|go:"GO:0070026"(nitric oxide binding)|go:"GO:0070814"(hydrogen sulfide biosynthetic process)|go:"GO:0072341"(modified amino acid binding)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR001216(Cysteine synthase/cystathionine beta-synthase P-phosphate-binding site)|interpro:IPR001926(Pyridoxal phosphate-dependent enzyme, beta subunit)|interpro:IPR005857(Cystathionine beta-synthase)|interpro:IPR036052|mint:P35520|rcsb pdb:1JBQ|rcsb pdb:1M54|rcsb pdb:4COO|rcsb pdb:4L0D|rcsb pdb:4L27|rcsb pdb:4L28|rcsb pdb:4L3V|rcsb pdb:4PCU|rcsb pdb:4UUU|rcsb pdb:5MMS|reactome:R-HSA-1614603|reactome:R-HSA-2408508|refseq:XP_011528079.1|refseq:XP_011528083.1|refseq:XP_011528084.1|refseq:XP_011544396.1|refseq:XP_011544397.1|refseq:XP_011544399.1|refseq:XP_011544400.1|refseq:XP_011544401.1|refseq:NP_001307227.1|refseq:NP_001308002.1|refseq:XP_016883700.1|refseq:XP_016883701.1|refseq:XP_016883702.1|refseq:XP_016883703.1|refseq:XP_016883704.1|refseq:XP_016883705.1|refseq:XP_016883706.1|refseq:XP_016883707.1|refseq:XP_016883978.1|refseq:XP_016883979.1|refseq:XP_016883980.1|refseq:XP_016883981.1|entrezgene/locuslink:875(identity)	refseq:NP_014210.1|sgd:S000005133|dip:DIP-728N|mint:Q02821|ensemblfungi:YNL189W(gene)|ensemblfungi:YNL189W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0031144"(proteasome localization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042564"(NLS-dependent protein nuclear import complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|rcsb pdb:1BK5|rcsb pdb:1BK6|rcsb pdb:1EE4|rcsb pdb:1EE5|rcsb pdb:1UN0|rcsb pdb:1WA5|rcsb pdb:2C1T|rcsb pdb:4PVZ|rcsb pdb:4XZR|rcsb pdb:5H2W|rcsb pdb:5H2X|rcsb pdb:5T94|sgd:YNL189W(identity)	-	-	crc64:8D3A0CB76F2E7C00	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:f9eo0cPOHppVY7Nqejag3YyK18s9606	rogid:NyzC93xnBCb8DX/AH346lwg4u2A559292	intact-crc:D9EE58E90688206D|rigid:sHjkU2Xr5Rp+0zmlZ6aoAynaMus	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P22234	uniprotkb:Q02821	intact:EBI-712261|ensembl:ENSP00000264221|ensembl:ENSP00000421096|uniprotkb:E9PDH9|uniprotkb:Q68CQ5|intact:EBI-21352784	intact:EBI-1797|uniprotkb:D6W0Z8|ensemblfungi:YNL189W	psi-mi:pur6_human(display_long)|uniprotkb:PAICS(gene name)|psi-mi:PAICS(display_short)|uniprotkb:ADE2(gene name synonym)|uniprotkb:AIRC(gene name synonym)|uniprotkb:PAIS(gene name synonym)	psi-mi:ima1_yeast(display_long)|uniprotkb:SRP1(gene name)|psi-mi:SRP1(display_short)|uniprotkb:KAP60(gene name synonym)|uniprotkb:YNL189W(locus name)|uniprotkb:N1606(orf name)|uniprotkb:Karyopherin subunit alpha(gene name synonym)|uniprotkb:Karyopherin-60(gene name synonym)|uniprotkb:Serine-rich RNA polymerase I suppressor protein(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11534435|imex:IM-24995-1266	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000128050(gene)|ensembl:ENST00000264221(transcript)|ensembl:ENST00000512576(transcript)|go:"GO:0004639"(phosphoribosylaminoimidazolesuccinocarboxamide synthase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006189"('de novo' IMP biosynthetic process)|go:"GO:0009113"(purine nucleobase biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043727"(5-amino-4-imidazole carboxylate lyase activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000031("1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase")|interpro:IPR018236|interpro:IPR028923|interpro:IPR033626|mint:P22234|rcsb pdb:2H31|rcsb pdb:6YB8|go:"GO:0004638"(phosphoribosylaminoimidazole carboxylase activity)|rcsb pdb:6YB9|reactome:R-HSA-73817|refseq:NP_001072992.1|refseq:NP_001072993.1|refseq:NP_006443.1|entrezgene/locuslink:10606(identity)	refseq:NP_014210.1|sgd:S000005133|dip:DIP-728N|mint:Q02821|ensemblfungi:YNL189W(gene)|ensemblfungi:YNL189W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0031144"(proteasome localization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042564"(NLS-dependent protein nuclear import complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|rcsb pdb:1BK5|rcsb pdb:1BK6|rcsb pdb:1EE4|rcsb pdb:1EE5|rcsb pdb:1UN0|rcsb pdb:1WA5|rcsb pdb:2C1T|rcsb pdb:4PVZ|rcsb pdb:4XZR|rcsb pdb:5H2W|rcsb pdb:5H2X|rcsb pdb:5T94|sgd:YNL189W(identity)	-	-	crc64:8D3A0CB76F2E7C00	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:aR4Xj14ZQrPiY8cldw5o9AvjkAo9606	rogid:NyzC93xnBCb8DX/AH346lwg4u2A559292	intact-crc:362B6188015D82A5|rigid:XSq92qAfiIwgMiiBbsb5w5CSRFU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q02821	uniprotkb:P20591	intact:EBI-1797|uniprotkb:D6W0Z8|ensemblfungi:YNL189W	intact:EBI-929476|uniprotkb:D3DSI8|uniprotkb:B2RDA5|uniprotkb:B3KU10|uniprotkb:C9IYV7|uniprotkb:C9J8D6|uniprotkb:C9JN19|uniprotkb:C9JN88|uniprotkb:C9JUL1|uniprotkb:C9JZS6|uniprotkb:Q86YP5|uniprotkb:Q96CI3|ensembl:ENSP00000381599|ensembl:ENSP00000381601|ensembl:ENSP00000392151|ensembl:ENSP00000402215|ensembl:ENSP00000408498|ensembl:ENSP00000410523|ensembl:ENSP00000505029|ensembl:ENSP00000505047|ensembl:ENSP00000505051|ensembl:ENSP00000505189|ensembl:ENSP00000505457|ensembl:ENSP00000505489|ensembl:ENSP00000505630|ensembl:ENSP00000505657|ensembl:ENSP00000505669|ensembl:ENSP00000505781|ensembl:ENSP00000505874|ensembl:ENSP00000506047|ensembl:ENSP00000506062|ensembl:ENSP00000506183|ensembl:ENSP00000506199|ensembl:ENSP00000506220|ensembl:ENSP00000506270|ensembl:ENSP00000506348|ensembl:ENSP00000506372|ensembl:ENSP00000506395|ensembl:ENSP00000506481|ensembl:ENSP00000506512|ensembl:ENSP00000506690|ensembl:ENSP00000506712	psi-mi:ima1_yeast(display_long)|uniprotkb:SRP1(gene name)|psi-mi:SRP1(display_short)|uniprotkb:KAP60(gene name synonym)|uniprotkb:YNL189W(locus name)|uniprotkb:N1606(orf name)|uniprotkb:Karyopherin subunit alpha(gene name synonym)|uniprotkb:Karyopherin-60(gene name synonym)|uniprotkb:Serine-rich RNA polymerase I suppressor protein(gene name synonym)	psi-mi:mx1_human(display_long)|uniprotkb:MX1(gene name)|psi-mi:MX1(display_short)|uniprotkb:Myxovirus resistance protein 1(gene name synonym)|uniprotkb:Interferon-regulated resistance GTP-binding protein MxA(gene name synonym)|uniprotkb:Interferon-induced protein p78(gene name synonym)|uniprotkb:Myxoma resistance protein 1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11534426|imex:IM-24995-1265	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014210.1|sgd:S000005133|dip:DIP-728N|mint:Q02821|ensemblfungi:YNL189W(gene)|ensemblfungi:YNL189W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0031144"(proteasome localization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042564"(NLS-dependent protein nuclear import complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|rcsb pdb:1BK5|rcsb pdb:1BK6|rcsb pdb:1EE4|rcsb pdb:1EE5|rcsb pdb:1UN0|rcsb pdb:1WA5|rcsb pdb:2C1T|rcsb pdb:4PVZ|rcsb pdb:4XZR|rcsb pdb:5H2W|rcsb pdb:5H2X|rcsb pdb:5T94|sgd:YNL189W(identity)	refseq:NP_001269849.1|refseq:NP_001138397.1|refseq:NP_001171517.1|refseq:NP_002453.2|refseq:XP_011527870.1|refseq:XP_005261037.1|refseq:XP_005261038.1|refseq:XP_005261039.1|refseq:XP_005261035.1|refseq:XP_005261036.1|refseq:XP_016883838.1|refseq:XP_016883839.1|dip:DIP-35694N|ensembl:ENSG00000157601(gene)|ensembl:ENST00000398598(transcript)|ensembl:ENST00000398600(transcript)|ensembl:ENST00000413778(transcript)|ensembl:ENST00000417963(transcript)|ensembl:ENST00000419044(transcript)|ensembl:ENST00000455164(transcript)|ensembl:ENST00000679445(transcript)|ensembl:ENST00000679464(transcript)|ensembl:ENST00000679543(transcript)|ensembl:ENST00000679626(transcript)|ensembl:ENST00000679705(transcript)|ensembl:ENST00000679911(transcript)|ensembl:ENST00000680176(transcript)|ensembl:ENST00000680182(transcript)|ensembl:ENST00000680347(transcript)|ensembl:ENST00000680364(transcript)|ensembl:ENST00000680536(transcript)|ensembl:ENST00000680629(transcript)|ensembl:ENST00000680760(transcript)|ensembl:ENST00000680776(transcript)|ensembl:ENST00000681039(transcript)|ensembl:ENST00000681191(transcript)|ensembl:ENST00000681266(transcript)|ensembl:ENST00000681415(transcript)|ensembl:ENST00000681607(transcript)|ensembl:ENST00000681671(transcript)|ensembl:ENST00000681849(transcript)|ensembl:ENST00000681857(transcript)|ensembl:ENST00000681867(transcript)|ensembl:ENST00000681896(transcript)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0003374"(dynamin family protein polymerization involved in mitochondrial fission)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0006952"(defense response)|go:"GO:0007165"(signal transduction)|go:"GO:0008017"(microtubule binding)|go:"GO:0009615"(response to virus)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016185"(synaptic vesicle budding from presynaptic endocytic zone membrane)|go:"GO:0030424"(axon)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031623"(receptor internalization)|go:"GO:0031965"(nuclear membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0034340"(response to type I interferon)|go:"GO:0042802"(identical protein binding)|go:"GO:0044327"(dendritic spine head)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0051607"(defense response to virus)|go:"GO:0061025"(membrane fusion)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:0098793"(presynapse)|go:"GO:0098844"(postsynaptic endocytic zone membrane)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:0140374"(antiviral innate immune response)|interpro:IPR000375(Dynamin central region)|interpro:IPR001401(Dynamin, GTPase region)|interpro:IPR003130(Dynamin GTPase effector)|interpro:IPR019762|interpro:IPR020850|interpro:IPR022812|interpro:IPR027417|interpro:IPR030381|mint:P20591|rcsb pdb:3LJB|rcsb pdb:3SZR|rcsb pdb:3ZYS|rcsb pdb:4P4S|rcsb pdb:4P4T|rcsb pdb:4P4U|rcsb pdb:5GTM|reactome:R-HSA-1169408|reactome:R-HSA-909733|entrezgene/locuslink:4599(identity)	-	crc64:8D3A0CB76F2E7C00	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:NyzC93xnBCb8DX/AH346lwg4u2A559292	rogid:9rO7Zyl6v0Kq3xw6MKbVefk1hCA9606	intact-crc:60A4CE92AE9706CB|rigid:Ss/YtFxCh1OwLwdQC3gxslONYCc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P13196	uniprotkb:Q02821	intact:EBI-3905054|ensembl:ENSP00000309259|ensembl:ENSP00000378416|ensembl:ENSP00000417719|ensembl:ENSP00000418779	intact:EBI-1797|uniprotkb:D6W0Z8|ensemblfungi:YNL189W	psi-mi:hem1_human(display_long)|uniprotkb:ALAS1(gene name)|psi-mi:ALAS1(display_short)|uniprotkb:ALAS3(gene name synonym)|uniprotkb:ALASH(gene name synonym)|uniprotkb:5-aminolevulinic acid synthase 1(gene name synonym)|uniprotkb:Delta-ALA synthase 1(gene name synonym)|uniprotkb:Delta-aminolevulinate synthase 1(gene name synonym)|uniprotkb:OK/SW-cl.121(orf name)	psi-mi:ima1_yeast(display_long)|uniprotkb:SRP1(gene name)|psi-mi:SRP1(display_short)|uniprotkb:KAP60(gene name synonym)|uniprotkb:YNL189W(locus name)|uniprotkb:N1606(orf name)|uniprotkb:Karyopherin subunit alpha(gene name synonym)|uniprotkb:Karyopherin-60(gene name synonym)|uniprotkb:Serine-rich RNA polymerase I suppressor protein(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11534417|imex:IM-24995-1264	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001291372.1|refseq:NP_001291373.1|refseq:NP_000679.1|refseq:NP_954635.1|go:"GO:0006783"(heme biosynthetic process)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0042541"(hemoglobin biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0048821"(erythrocyte development)|ensembl:ENSG00000023330(gene)|ensembl:ENST00000310271(transcript)|ensembl:ENST00000394965(transcript)|ensembl:ENST00000469224(transcript)|ensembl:ENST00000484952(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0003870"(5-aminolevulinate synthase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|interpro:IPR001917(Aminotransferase, class-II, pyridoxal-phosphate binding site)|interpro:IPR004839(Aminotransferase, class I and II)|interpro:IPR010961(Tetrapyrrole biosynthesis, 5-aminolevulinic acid synthase)|interpro:IPR015118(5-aminolevulinate synthase presequence)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|mint:P13196|reactome:R-HSA-189451|reactome:R-HSA-1989781|reactome:R-HSA-2151201|go:"GO:0006782"(protoporphyrinogen IX biosynthetic process)|entrezgene/locuslink:211(identity)	refseq:NP_014210.1|sgd:S000005133|dip:DIP-728N|mint:Q02821|ensemblfungi:YNL189W(gene)|ensemblfungi:YNL189W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0031144"(proteasome localization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042564"(NLS-dependent protein nuclear import complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|rcsb pdb:1BK5|rcsb pdb:1BK6|rcsb pdb:1EE4|rcsb pdb:1EE5|rcsb pdb:1UN0|rcsb pdb:1WA5|rcsb pdb:2C1T|rcsb pdb:4PVZ|rcsb pdb:4XZR|rcsb pdb:5H2W|rcsb pdb:5H2X|rcsb pdb:5T94|sgd:YNL189W(identity)	-	-	crc64:8D3A0CB76F2E7C00	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:HFjJ6zrRF9UYD7LMB6A3CcxcS7c9606	rogid:NyzC93xnBCb8DX/AH346lwg4u2A559292	intact-crc:420A8478BA6CEDC2|rigid:I1igYh7FqhViL3owJKuaKs/NN4g	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q02821	uniprotkb:Q13557-8	intact:EBI-1797|uniprotkb:D6W0Z8|ensemblfungi:YNL189W	intact:EBI-11534483|ensembl:ENSP00000296402|ensembl:ENSP00000369098	psi-mi:ima1_yeast(display_long)|uniprotkb:SRP1(gene name)|psi-mi:SRP1(display_short)|uniprotkb:KAP60(gene name synonym)|uniprotkb:YNL189W(locus name)|uniprotkb:N1606(orf name)|uniprotkb:Karyopherin subunit alpha(gene name synonym)|uniprotkb:Karyopherin-60(gene name synonym)|uniprotkb:Serine-rich RNA polymerase I suppressor protein(gene name synonym)	psi-mi:q13557-8(display_long)|uniprotkb:CAMKD(gene name synonym)|uniprotkb:CAMK2D(gene name)|psi-mi:CAMK2D(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11534487|imex:IM-24995-1271	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014210.1|sgd:S000005133|dip:DIP-728N|mint:Q02821|ensemblfungi:YNL189W(gene)|ensemblfungi:YNL189W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0031144"(proteasome localization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042564"(NLS-dependent protein nuclear import complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|rcsb pdb:1BK5|rcsb pdb:1BK6|rcsb pdb:1EE4|rcsb pdb:1EE5|rcsb pdb:1UN0|rcsb pdb:1WA5|rcsb pdb:2C1T|rcsb pdb:4PVZ|rcsb pdb:4XZR|rcsb pdb:5H2W|rcsb pdb:5H2X|rcsb pdb:5T94|sgd:YNL189W(identity)	intact:EBI-351018(isoform-parent)|ensembl:ENSG00000145349(gene)|ensembl:ENST00000296402(transcript)|ensembl:ENST00000379773(transcript)|uniprotkb:Q13557-8(isoform-parent)|entrezgene/locuslink:817(identity)	-	crc64:8D3A0CB76F2E7C00	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:NyzC93xnBCb8DX/AH346lwg4u2A559292	rogid:44T/I8JdalScCNE5Vp/H+PnfdFo9606	intact-crc:6FB7223AC7456923|rigid:Vp8do7OhElgVpphFHYjWx5CkT18	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q13137	uniprotkb:Q02821	intact:EBI-739580|uniprotkb:B4DDC4|uniprotkb:E7ENK0|uniprotkb:Q53FQ5|uniprotkb:Q53HB5|uniprotkb:Q6IBN9|uniprotkb:Q9BTF7|uniprotkb:B2RBT0|ensembl:ENSP00000258947|uniprotkb:B4E0C0|uniprotkb:E7ETP5|uniprotkb:B4DDT4|uniprotkb:B4DP36|uniprotkb:E9PBE5	intact:EBI-1797|uniprotkb:D6W0Z8|ensemblfungi:YNL189W	psi-mi:caco2_human(display_long)|uniprotkb:CALCOCO2(gene name)|psi-mi:CALCOCO2(display_short)|uniprotkb:NDP52(gene name synonym)|uniprotkb:Nuclear domain 10 protein NDP52(gene name synonym)|uniprotkb:Antigen nuclear dot 52 kDa protein(gene name synonym)|uniprotkb:Nuclear dot protein 52(gene name synonym)	psi-mi:ima1_yeast(display_long)|uniprotkb:SRP1(gene name)|psi-mi:SRP1(display_short)|uniprotkb:KAP60(gene name synonym)|uniprotkb:YNL189W(locus name)|uniprotkb:N1606(orf name)|uniprotkb:Karyopherin subunit alpha(gene name synonym)|uniprotkb:Karyopherin-60(gene name synonym)|uniprotkb:Serine-rich RNA polymerase I suppressor protein(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11534474|imex:IM-24995-1270	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001248319.1|refseq:NP_001248320.1|refseq:NP_001248322.1|refseq:NP_005822.1|ensembl:ENSG00000136436(gene)|ensembl:ENST00000258947(transcript)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016032"(viral process)|go:"GO:0016605"(PML body)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0098792"(xenophagy)|go:"GO:1901098"(positive regulation of autophagosome maturation)|interpro:IPR041611|interpro:IPR041641|mint:Q13137|rcsb pdb:2MXP|rcsb pdb:3VVV|rcsb pdb:3VVW|rcsb pdb:4GXL|rcsb pdb:4HAN|rcsb pdb:4XKL|rcsb pdb:5AAQ|rcsb pdb:5Z7A|rcsb pdb:5Z7L|refseq:NP_001248324.1|dip:DIP-57534N|entrezgene/locuslink:10241(identity)	refseq:NP_014210.1|sgd:S000005133|dip:DIP-728N|mint:Q02821|ensemblfungi:YNL189W(gene)|ensemblfungi:YNL189W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0031144"(proteasome localization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042564"(NLS-dependent protein nuclear import complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|rcsb pdb:1BK5|rcsb pdb:1BK6|rcsb pdb:1EE4|rcsb pdb:1EE5|rcsb pdb:1UN0|rcsb pdb:1WA5|rcsb pdb:2C1T|rcsb pdb:4PVZ|rcsb pdb:4XZR|rcsb pdb:5H2W|rcsb pdb:5H2X|rcsb pdb:5T94|sgd:YNL189W(identity)	-	crc64:609B121DA1A9DCB8	crc64:8D3A0CB76F2E7C00	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:N/GPJUGBK+Dh5Cg+csmafphuo9M9606	rogid:NyzC93xnBCb8DX/AH346lwg4u2A559292	intact-crc:7070397BE4384DCF|rigid:hHMSqSo0VC7VlXnaDmX0YbMFn94	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P63261	uniprotkb:Q02821	intact:EBI-351292|uniprotkb:P02571|uniprotkb:P14104|uniprotkb:P99022|uniprotkb:Q5U032|uniprotkb:Q96E67|uniprotkb:A8K7C2|ensembl:ENSP00000505060|ensembl:ENSP00000505193|ensembl:ENSP00000505235|ensembl:ENSP00000506126|ensembl:ENSP00000506201|ensembl:ENSP00000506253|ensembl:ENSP00000458162|ensembl:ENSP00000458435|ensembl:ENSP00000459119|ensembl:ENSP00000459124|ensembl:ENSP00000460464|ensembl:ENSP00000460660|ensembl:ENSP00000461672|ensembl:ENSP00000466346|ensembl:ENSP00000477968	intact:EBI-1797|uniprotkb:D6W0Z8|ensemblfungi:YNL189W	psi-mi:actg_human(display_long)|uniprotkb:ACTG1(gene name)|psi-mi:ACTG1(display_short)|uniprotkb:ACTG(gene name synonym)|uniprotkb:Gamma-actin(gene name synonym)	psi-mi:ima1_yeast(display_long)|uniprotkb:SRP1(gene name)|psi-mi:SRP1(display_short)|uniprotkb:KAP60(gene name synonym)|uniprotkb:YNL189W(locus name)|uniprotkb:N1606(orf name)|uniprotkb:Karyopherin subunit alpha(gene name synonym)|uniprotkb:Karyopherin-60(gene name synonym)|uniprotkb:Serine-rich RNA polymerase I suppressor protein(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11534464|imex:IM-24995-1269	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001186883.1|refseq:NP_001605.1|ensembl:ENST00000570382(transcript)|ensembl:ENSG00000184009(gene)|ensembl:ENST00000571721(transcript)|ensembl:ENST00000573283(transcript)|ensembl:ENST00000575087(transcript)|ensembl:ENST00000575659(transcript)|ensembl:ENST00000575842(transcript)|ensembl:ENST00000575994(transcript)|ensembl:ENST00000576544(transcript)|ensembl:ENST00000615544(transcript)|ensembl:ENST00000679480(transcript)|ensembl:ENST00000679778(transcript)|ensembl:ENST00000680227(transcript)|ensembl:ENST00000680727(transcript)|ensembl:ENST00000681052(transcript)|ensembl:ENST00000681842(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0001895"(retina homeostasis)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005522"(profilin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0030016"(myofibril)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031941"(filamentous actin)|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0044305"(calyx of Held)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0051492"(regulation of stress fiber assembly)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070527"(platelet aggregation)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0072562"(blood microparticle)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0097433"(dense body)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098973"(structural constituent of postsynaptic actin cytoskeleton)|go:"GO:0120192"(tight junction assembly)|go:"GO:0120220"(basal body patch)|go:"GO:0150111"(regulation of transepithelial transport)|go:"GO:1902396"(protein localization to bicellular tight junction)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P63261|rcsb pdb:5JLH|rcsb pdb:6CXI|rcsb pdb:6CXJ|rcsb pdb:6G2T|rcsb pdb:6V62|rcsb pdb:6V63|rcsb pdb:6WK1|rcsb pdb:6WK2|reactome:R-HSA-1445148|reactome:R-HSA-190873|reactome:R-HSA-196025|reactome:R-HSA-2029482|reactome:R-HSA-3928662|reactome:R-HSA-3928665|reactome:R-HSA-418990|reactome:R-HSA-437239|reactome:R-HSA-4420097|reactome:R-HSA-445095|reactome:R-HSA-446353|reactome:R-HSA-5626467|reactome:R-HSA-5663213|reactome:R-HSA-5663220|reactome:R-HSA-5674135|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8856828|reactome:R-HSA-9013418|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9662360|reactome:R-HSA-9662361|reactome:R-HSA-9664422|entrezgene/locuslink:71(identity)	refseq:NP_014210.1|sgd:S000005133|dip:DIP-728N|mint:Q02821|ensemblfungi:YNL189W(gene)|ensemblfungi:YNL189W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0031144"(proteasome localization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042564"(NLS-dependent protein nuclear import complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|rcsb pdb:1BK5|rcsb pdb:1BK6|rcsb pdb:1EE4|rcsb pdb:1EE5|rcsb pdb:1UN0|rcsb pdb:1WA5|rcsb pdb:2C1T|rcsb pdb:4PVZ|rcsb pdb:4XZR|rcsb pdb:5H2W|rcsb pdb:5H2X|rcsb pdb:5T94|sgd:YNL189W(identity)	-	-	crc64:8D3A0CB76F2E7C00	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:B2OOsE06lTfo90H3g8tlmUJQ7cY9606	rogid:NyzC93xnBCb8DX/AH346lwg4u2A559292	intact-crc:A84DC0BD04E216AC|rigid:eAmSecUW+kV9D40b0fX57lQh+ZU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q02821	uniprotkb:Q9NS73	intact:EBI-1797|uniprotkb:D6W0Z8|ensemblfungi:YNL189W	intact:EBI-741953|uniprotkb:Q86TZ2|uniprotkb:Q96AS5|uniprotkb:Q9BS93|uniprotkb:Q9NZE1|ensembl:ENSP00000399718	psi-mi:ima1_yeast(display_long)|uniprotkb:SRP1(gene name)|psi-mi:SRP1(display_short)|uniprotkb:KAP60(gene name synonym)|uniprotkb:YNL189W(locus name)|uniprotkb:N1606(orf name)|uniprotkb:Karyopherin subunit alpha(gene name synonym)|uniprotkb:Karyopherin-60(gene name synonym)|uniprotkb:Serine-rich RNA polymerase I suppressor protein(gene name synonym)	psi-mi:mbip1_human(display_long)|uniprotkb:MAPK upstream kinase-binding inhibitory protein(gene name synonym)|uniprotkb:MBIP(gene name)|psi-mi:MBIP(display_short)|uniprotkb:BM-015(orf name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11534541|imex:IM-24995-1277	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014210.1|sgd:S000005133|dip:DIP-728N|mint:Q02821|ensemblfungi:YNL189W(gene)|ensemblfungi:YNL189W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0031144"(proteasome localization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042564"(NLS-dependent protein nuclear import complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|rcsb pdb:1BK5|rcsb pdb:1BK6|rcsb pdb:1EE4|rcsb pdb:1EE5|rcsb pdb:1UN0|rcsb pdb:1WA5|rcsb pdb:2C1T|rcsb pdb:4PVZ|rcsb pdb:4XZR|rcsb pdb:5H2W|rcsb pdb:5H2X|rcsb pdb:5T94|sgd:YNL189W(identity)	refseq:NP_001138363.1|refseq:NP_057670.2|ensembl:ENSG00000151332(gene)|ensembl:ENST00000416007(transcript)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0042802"(identical protein binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0046330"(positive regulation of JNK cascade)|interpro:IPR026062|mint:Q9NS73|reactome:R-HSA-3214847|go:"GO:0005654"(nucleoplasm)|refseq:NP_001295039.1|entrezgene/locuslink:51562(identity)	-	crc64:8D3A0CB76F2E7C00	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:NyzC93xnBCb8DX/AH346lwg4u2A559292	rogid:PjaEuab6wwOyGImpNYFZfQ+TUvU9606	intact-crc:287B91B3675DB0FD|rigid:QDAkj1JjcjC1M6fXPGwGjxHqPWE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9HAN9	uniprotkb:Q02821	intact:EBI-3917542|uniprotkb:Q8TAE9|uniprotkb:Q9H6B6|uniprotkb:Q9H247|uniprotkb:B1AN63|ensembl:ENSP00000366410|ensembl:ENSP00000435134	intact:EBI-1797|uniprotkb:D6W0Z8|ensemblfungi:YNL189W	psi-mi:nmna1_human(display_long)|uniprotkb:NMNAT1(gene name)|psi-mi:NMNAT1(display_short)|uniprotkb:NMNAT(gene name synonym)|uniprotkb:Nicotinate-nucleotide adenylyltransferase 1(gene name synonym)|uniprotkb:Nicotinamide-nucleotide adenylyltransferase 1(gene name synonym)	psi-mi:ima1_yeast(display_long)|uniprotkb:SRP1(gene name)|psi-mi:SRP1(display_short)|uniprotkb:KAP60(gene name synonym)|uniprotkb:YNL189W(locus name)|uniprotkb:N1606(orf name)|uniprotkb:Karyopherin subunit alpha(gene name synonym)|uniprotkb:Karyopherin-60(gene name synonym)|uniprotkb:Serine-rich RNA polymerase I suppressor protein(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11534532|imex:IM-24995-1276	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001284707.1|refseq:NP_073624.2|ensembl:ENSG00000173614(gene)|ensembl:ENST00000377205(transcript)|ensembl:ENST00000462686(transcript)|go:"GO:0000309"(nicotinamide-nucleotide adenylyltransferase activity)|go:"GO:0004515"(nicotinate-nucleotide adenylyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0009165"(nucleotide biosynthetic process)|go:"GO:0009435"(NAD biosynthetic process)|go:"GO:0009611"(response to wounding)|go:"GO:0016604"(nuclear body)|go:"GO:0042802"(identical protein binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:1902511"(negative regulation of apoptotic DNA fragmentation)|go:"GO:1990966"(ATP generation from poly-ADP-D-ribose)|interpro:IPR004821(Cytidyltransferase-related)|interpro:IPR005248(Probable nicotinate-nucleotide adenylyltransferase)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|mint:Q9HAN9|rcsb pdb:1GZU|rcsb pdb:1KKU|rcsb pdb:1KQN|rcsb pdb:1KQO|rcsb pdb:1KR2|reactome:R-HSA-196807|refseq:XP_016857596.1|dip:DIP-60881N|entrezgene/locuslink:64802(identity)	refseq:NP_014210.1|sgd:S000005133|dip:DIP-728N|mint:Q02821|ensemblfungi:YNL189W(gene)|ensemblfungi:YNL189W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0031144"(proteasome localization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042564"(NLS-dependent protein nuclear import complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|rcsb pdb:1BK5|rcsb pdb:1BK6|rcsb pdb:1EE4|rcsb pdb:1EE5|rcsb pdb:1UN0|rcsb pdb:1WA5|rcsb pdb:2C1T|rcsb pdb:4PVZ|rcsb pdb:4XZR|rcsb pdb:5H2W|rcsb pdb:5H2X|rcsb pdb:5T94|sgd:YNL189W(identity)	-	-	crc64:8D3A0CB76F2E7C00	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:KwV9lz04z3ptlVpKu3b534Yekpc9606	rogid:NyzC93xnBCb8DX/AH346lwg4u2A559292	intact-crc:7A0A5D04D68A3024|rigid:hiVoR93U7NxzHo9Ck1njCpBKh28	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8WVF5	uniprotkb:Q02821	intact:EBI-741463|ensembl:ENSP00000368402|uniprotkb:Q5W0P9	intact:EBI-1797|uniprotkb:D6W0Z8|ensemblfungi:YNL189W	psi-mi:kctd4_human(display_long)|uniprotkb:KCTD4(gene name)|psi-mi:KCTD4(display_short)	psi-mi:ima1_yeast(display_long)|uniprotkb:SRP1(gene name)|psi-mi:SRP1(display_short)|uniprotkb:KAP60(gene name synonym)|uniprotkb:YNL189W(locus name)|uniprotkb:N1606(orf name)|uniprotkb:Karyopherin subunit alpha(gene name synonym)|uniprotkb:Karyopherin-60(gene name synonym)|uniprotkb:Serine-rich RNA polymerase I suppressor protein(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11534523|imex:IM-24995-1275	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000180332(gene)|ensembl:ENST00000379108(transcript)|go:"GO:0051260"(protein homooligomerization)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR003131(Potassium channel, voltage dependent, Kv,  tetramerisation)|interpro:IPR011333(BTB/POZ fold)|refseq:NP_940686.2|entrezgene/locuslink:386618(identity)	refseq:NP_014210.1|sgd:S000005133|dip:DIP-728N|mint:Q02821|ensemblfungi:YNL189W(gene)|ensemblfungi:YNL189W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0031144"(proteasome localization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042564"(NLS-dependent protein nuclear import complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|rcsb pdb:1BK5|rcsb pdb:1BK6|rcsb pdb:1EE4|rcsb pdb:1EE5|rcsb pdb:1UN0|rcsb pdb:1WA5|rcsb pdb:2C1T|rcsb pdb:4PVZ|rcsb pdb:4XZR|rcsb pdb:5H2W|rcsb pdb:5H2X|rcsb pdb:5T94|sgd:YNL189W(identity)	-	-	crc64:8D3A0CB76F2E7C00	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:03cd1lqmT8fReXzYqjrKSWUdqY89606	rogid:NyzC93xnBCb8DX/AH346lwg4u2A559292	intact-crc:73D53B649602A9AB|rigid:6KdU4mjtwdu6qyVglZVNc05/CUs	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q02821	uniprotkb:Q15041	intact:EBI-1797|uniprotkb:D6W0Z8|ensemblfungi:YNL189W	intact:EBI-714543|ensembl:ENSP00000306788|uniprotkb:B7Z6S5|uniprotkb:B7Z791|uniprotkb:F5GXP4	psi-mi:ima1_yeast(display_long)|uniprotkb:SRP1(gene name)|psi-mi:SRP1(display_short)|uniprotkb:KAP60(gene name synonym)|uniprotkb:YNL189W(locus name)|uniprotkb:N1606(orf name)|uniprotkb:Karyopherin subunit alpha(gene name synonym)|uniprotkb:Karyopherin-60(gene name synonym)|uniprotkb:Serine-rich RNA polymerase I suppressor protein(gene name synonym)	psi-mi:ar6p1_human(display_long)|uniprotkb:ARL6IP(gene name synonym)|uniprotkb:ARL6IP1(gene name)|psi-mi:ARL6IP1(display_short)|uniprotkb:KIAA0069(gene name synonym)|uniprotkb:ARMER(gene name synonym)|uniprotkb:Apoptotic regulator in the membrane of the endoplasmic reticulum(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11534514|imex:IM-24995-1274	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014210.1|sgd:S000005133|dip:DIP-728N|mint:Q02821|ensemblfungi:YNL189W(gene)|ensemblfungi:YNL189W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0031144"(proteasome localization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042564"(NLS-dependent protein nuclear import complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|rcsb pdb:1BK5|rcsb pdb:1BK6|rcsb pdb:1EE4|rcsb pdb:1EE5|rcsb pdb:1UN0|rcsb pdb:1WA5|rcsb pdb:2C1T|rcsb pdb:4PVZ|rcsb pdb:4XZR|rcsb pdb:5H2W|rcsb pdb:5H2X|rcsb pdb:5T94|sgd:YNL189W(identity)	refseq:NP_055976.1|ensembl:ENSG00000170540(gene)|ensembl:ENST00000304414(transcript)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006613"(cotranslational protein targeting to membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0071787"(endoplasmic reticulum tubular network formation)|go:"GO:1903371"(regulation of endoplasmic reticulum tubular network organization)|go:"GO:1990809"(endoplasmic reticulum tubular network membrane organization)|interpro:IPR033301|mint:Q15041|go:"GO:0002038"(positive regulation of L-glutamate import across plasma membrane)|refseq:NP_001300787.1|entrezgene/locuslink:23204(identity)	-	crc64:8D3A0CB76F2E7C00	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:NyzC93xnBCb8DX/AH346lwg4u2A559292	rogid:3fjkoyvUx25po7xsPcXgpjEeLJg9606	intact-crc:1576A006B4945CC1|rigid:IgRYyzm7Dnd+YxZ8YMSEE+zMZNs	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q02821	uniprotkb:Q15038	intact:EBI-1797|uniprotkb:D6W0Z8|ensemblfungi:YNL189W	intact:EBI-724310|ensembl:ENSP00000394699|uniprotkb:E9PB45|uniprotkb:A8K254|uniprotkb:B4DDT5|uniprotkb:C9JA96|uniprotkb:C9JP84|uniprotkb:B4E1G3|uniprotkb:F8VU62	psi-mi:ima1_yeast(display_long)|uniprotkb:SRP1(gene name)|psi-mi:SRP1(display_short)|uniprotkb:KAP60(gene name synonym)|uniprotkb:YNL189W(locus name)|uniprotkb:N1606(orf name)|uniprotkb:Karyopherin subunit alpha(gene name synonym)|uniprotkb:Karyopherin-60(gene name synonym)|uniprotkb:Serine-rich RNA polymerase I suppressor protein(gene name synonym)	psi-mi:dazp2_human(display_long)|uniprotkb:Deleted in azoospermia-associated protein 2(gene name synonym)|uniprotkb:DAZAP2(gene name)|psi-mi:DAZAP2(display_short)|uniprotkb:KIAA0058(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11534505|imex:IM-24995-1273	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014210.1|sgd:S000005133|dip:DIP-728N|mint:Q02821|ensemblfungi:YNL189W(gene)|ensemblfungi:YNL189W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0031144"(proteasome localization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042564"(NLS-dependent protein nuclear import complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|rcsb pdb:1BK5|rcsb pdb:1BK6|rcsb pdb:1EE4|rcsb pdb:1EE5|rcsb pdb:1UN0|rcsb pdb:1WA5|rcsb pdb:2C1T|rcsb pdb:4PVZ|rcsb pdb:4XZR|rcsb pdb:5H2W|rcsb pdb:5H2X|rcsb pdb:5T94|sgd:YNL189W(identity)	ensembl:ENSG00000183283(gene)|ensembl:ENST00000412716(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0016607"(nuclear speck)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0050699"(WW domain binding)|interpro:IPR022730|mint:Q15038|refseq:NP_001129736.1|refseq:NP_055579.1|ensembl:ENSP00000394699|ensembl:ENST00000425012|ensembl:ENSP00000408251|ensembl:ENST00000439799|ensembl:ENSP00000398804|ensembl:ENST00000449723|ensembl:ENSP00000412812|ensembl:ENST00000549555|ensembl:ENSP00000448051|ensembl:ENST00000549732|ensembl:ENSP00000446554|refseq:NP_001129741.1|refseq:NP_001129739.1|refseq:NP_001129740.1|refseq:NP_001129738.1|entrezgene/locuslink:9802(identity)	-	crc64:8D3A0CB76F2E7C00	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:NyzC93xnBCb8DX/AH346lwg4u2A559292	rogid:ASRqCZBG4q1U/y95PUSMKsgfm/g9606	intact-crc:207B7EF63FDAB0D8|rigid:yCLVefhV7x77d29dFaxQHSx62kQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q13867	uniprotkb:Q02821	intact:EBI-718504|uniprotkb:Q53F86|uniprotkb:Q9UER9|uniprotkb:B2R796|ensembl:ENSP00000261714	intact:EBI-1797|uniprotkb:D6W0Z8|ensemblfungi:YNL189W	psi-mi:blmh_human(display_long)|uniprotkb:BLMH(gene name)|psi-mi:BLMH(display_short)	psi-mi:ima1_yeast(display_long)|uniprotkb:SRP1(gene name)|psi-mi:SRP1(display_short)|uniprotkb:KAP60(gene name synonym)|uniprotkb:YNL189W(locus name)|uniprotkb:N1606(orf name)|uniprotkb:Karyopherin subunit alpha(gene name synonym)|uniprotkb:Karyopherin-60(gene name synonym)|uniprotkb:Serine-rich RNA polymerase I suppressor protein(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11534496|imex:IM-24995-1272	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000377.1|ensembl:ENSG00000108578(gene)|ensembl:ENST00000261714(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004177"(aminopeptidase activity)|go:"GO:0004180"(carboxypeptidase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006508"(proteolysis)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0009636"(response to toxic substance)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043418"(homocysteine catabolic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000169(Peptidase, cysteine peptidase active site)|interpro:IPR004134(Peptidase C1B, bleomycin hydrolase)|interpro:IPR038765|mint:Q13867|rcsb pdb:1CB5|rcsb pdb:2CB5|reactome:R-HSA-983168|entrezgene/locuslink:642(identity)	refseq:NP_014210.1|sgd:S000005133|dip:DIP-728N|mint:Q02821|ensemblfungi:YNL189W(gene)|ensemblfungi:YNL189W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0031144"(proteasome localization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042564"(NLS-dependent protein nuclear import complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|rcsb pdb:1BK5|rcsb pdb:1BK6|rcsb pdb:1EE4|rcsb pdb:1EE5|rcsb pdb:1UN0|rcsb pdb:1WA5|rcsb pdb:2C1T|rcsb pdb:4PVZ|rcsb pdb:4XZR|rcsb pdb:5H2W|rcsb pdb:5H2X|rcsb pdb:5T94|sgd:YNL189W(identity)	-	-	crc64:8D3A0CB76F2E7C00	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:THDv63DC81eQzFvmyWs1rlCBMyk9606	rogid:NyzC93xnBCb8DX/AH346lwg4u2A559292	intact-crc:9DE7580E0576A610|rigid:mXEqsbkDTq9X7I09Sl2jwXhN0bE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q08379	uniprotkb:Q02831	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	intact:EBI-31828|uniprotkb:D6W3T9|ensemblfungi:YPL077C	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:yp077_yeast(display_long)|uniprotkb:YPL077C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11534568|imex:IM-24995-1280	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N|entrezgene/locuslink:2801(identity)	sgd:S000005998|refseq:NP_015248.1|dip:DIP-4022N|ensemblfungi:YPL077C(gene)|ensemblfungi:YPL077C_mRNA(transcript)|sgd:YPL077C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2017/05/26	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	rogid:yqOn4GWKNmFZ7UvGmyBEpgoyKlA559292	intact-crc:C587E8B4E24A6549|rigid:MRpEjW2Eb4yYRpTVVIPB+VFwef8	false	sufficient binding region:383-1002	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9NVV9	uniprotkb:Q02821	intact:EBI-741515|uniprotkb:Q53FQ1|uniprotkb:Q6IA99|ensembl:ENSP00000254250|uniprotkb:A6NCB6|uniprotkb:D3DSY5|uniprotkb:H9KV49	intact:EBI-1797|uniprotkb:D6W0Z8|ensemblfungi:YNL189W	psi-mi:thap1_human(display_long)|uniprotkb:THAP1(gene name)|psi-mi:THAP1(display_short)	psi-mi:ima1_yeast(display_long)|uniprotkb:SRP1(gene name)|psi-mi:SRP1(display_short)|uniprotkb:KAP60(gene name synonym)|uniprotkb:YNL189W(locus name)|uniprotkb:N1606(orf name)|uniprotkb:Karyopherin subunit alpha(gene name synonym)|uniprotkb:Karyopherin-60(gene name synonym)|uniprotkb:Serine-rich RNA polymerase I suppressor protein(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11534559|imex:IM-24995-1279	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060575.1|ensembl:ENSG00000131931(gene)|ensembl:ENST00000254250(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001650"(fibrillar center)|go:"GO:0001935"(endothelial cell proliferation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007049"(cell cycle)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016605"(PML body)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR006612(Zinc finger, C2CH-type)|interpro:IPR026516|interpro:IPR038441|mint:Q9NVV9|rcsb pdb:2JTG|rcsb pdb:2KO0|rcsb pdb:2L1G|refseq:NP_945354.1|entrezgene/locuslink:55145(identity)	refseq:NP_014210.1|sgd:S000005133|dip:DIP-728N|mint:Q02821|ensemblfungi:YNL189W(gene)|ensemblfungi:YNL189W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0031144"(proteasome localization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042564"(NLS-dependent protein nuclear import complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|rcsb pdb:1BK5|rcsb pdb:1BK6|rcsb pdb:1EE4|rcsb pdb:1EE5|rcsb pdb:1UN0|rcsb pdb:1WA5|rcsb pdb:2C1T|rcsb pdb:4PVZ|rcsb pdb:4XZR|rcsb pdb:5H2W|rcsb pdb:5H2X|rcsb pdb:5T94|sgd:YNL189W(identity)	-	-	crc64:8D3A0CB76F2E7C00	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:/KO90pu5tBnIVq9SMx1JYPXFCEQ9606	rogid:NyzC93xnBCb8DX/AH346lwg4u2A559292	intact-crc:1AF40E21440EA567|rigid:x/UGKue0dWbjDEhVKK+hw+DNx6Q	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q02821	uniprotkb:Q9NS73-5	intact:EBI-1797|uniprotkb:D6W0Z8|ensemblfungi:YNL189W	intact:EBI-10182361|ensembl:ENSP00000324444	psi-mi:ima1_yeast(display_long)|uniprotkb:SRP1(gene name)|psi-mi:SRP1(display_short)|uniprotkb:KAP60(gene name synonym)|uniprotkb:YNL189W(locus name)|uniprotkb:N1606(orf name)|uniprotkb:Karyopherin subunit alpha(gene name synonym)|uniprotkb:Karyopherin-60(gene name synonym)|uniprotkb:Serine-rich RNA polymerase I suppressor protein(gene name synonym)	psi-mi:q9ns73-5(display_long)|uniprotkb:MAPK upstream kinase-binding inhibitory protein(gene name synonym)|uniprotkb:BM-015(orf name)|uniprotkb:MBIP(gene name)|psi-mi:MBIP(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11534550|imex:IM-24995-1278	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014210.1|sgd:S000005133|dip:DIP-728N|mint:Q02821|ensemblfungi:YNL189W(gene)|ensemblfungi:YNL189W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0031144"(proteasome localization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042564"(NLS-dependent protein nuclear import complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|rcsb pdb:1BK5|rcsb pdb:1BK6|rcsb pdb:1EE4|rcsb pdb:1EE5|rcsb pdb:1UN0|rcsb pdb:1WA5|rcsb pdb:2C1T|rcsb pdb:4PVZ|rcsb pdb:4XZR|rcsb pdb:5H2W|rcsb pdb:5H2X|rcsb pdb:5T94|sgd:YNL189W(identity)	ensembl:ENSG00000151332(gene)|ensembl:ENST00000318473(transcript)|intact:EBI-741953(isoform-parent)|uniprotkb:Q9NS73-5(isoform-parent)|entrezgene/locuslink:51562(identity)	-	crc64:8D3A0CB76F2E7C00	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:NyzC93xnBCb8DX/AH346lwg4u2A559292	rogid:JVmcJrT3SXRZwv9U285cNqnXWQE9606	intact-crc:4A18D4E8AC5D6A35|rigid:keYNqWVWUF9B+O6/G0K2ascnBwA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q02831	uniprotkb:P37198	intact:EBI-31828|uniprotkb:D6W3T9|ensemblfungi:YPL077C	intact:EBI-347978|intact:EBI-28983799|ensembl:ENSP00000305503|ensembl:ENSP00000407331|ensembl:ENSP00000471191|ensembl:ENSP00000473192|uniprotkb:Q6GTM2|uniprotkb:Q503A4|uniprotkb:Q96C43|uniprotkb:Q9NSL1|uniprotkb:B3KWU5	psi-mi:yp077_yeast(display_long)|uniprotkb:YPL077C(locus name)	psi-mi:nup62_human(display_long)|uniprotkb:NUP62(gene name)|psi-mi:NUP62(display_short)|uniprotkb:62 kDa nucleoporin(gene name synonym)|uniprotkb:Nucleoporin Nup62(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11534617|imex:IM-24995-1285	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005998|refseq:NP_015248.1|dip:DIP-4022N|ensemblfungi:YPL077C(gene)|ensemblfungi:YPL077C_mRNA(transcript)|sgd:YPL077C(identity)	refseq:NP_714941.1|ensembl:ENSG00000213024(gene)|ensembl:ENST00000352066(transcript)|ensembl:ENST00000422090(transcript)|ensembl:ENST00000596217(transcript)|ensembl:ENST00000597029(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005642"(annulate lamellae)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007100"(mitotic centrosome separation)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007569"(cell aging)|go:"GO:0008219"(cell death)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0003682"(chromatin binding)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0019894"(kinesin binding)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042306"(regulation of protein import into nucleus)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043069"(negative regulation of programmed cell death)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045742"(positive regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046578"(regulation of Ras protein signal transduction)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0046601"(positive regulation of centriole replication)|go:"GO:0051028"(mRNA transport)|go:"GO:0051425"(PTB domain binding)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0072686"(mitotic spindle)|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|go:"GO:0090543"(Flemming body)|go:"GO:0098534"(centriole assembly)|go:"GO:1903438"(positive regulation of mitotic cytokinetic process)|go:"GO:1904781"(positive regulation of protein localization to centrosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR007758(Nucleoporin, Nsp1-like, C-terminal)|interpro:IPR026010|interpro:IPR033072|mint:P37198|rcsb pdb:2H4D|rcsb pdb:5IJN|rcsb pdb:5IJO|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|refseq:NP_714940.1|refseq:NP_001180286.1|refseq:NP_036478.2|refseq:NP_057637.2|ensembl:ENSP00000305503|ensembl:ENSP00000407331|ensembl:ENSP00000471191|ensembl:ENSP00000473192|dip:DIP-29749N|entrezgene/locuslink:23636(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:yqOn4GWKNmFZ7UvGmyBEpgoyKlA559292	rogid:v7mvKvTtVEnLMwcpUZIcdAzge009606	intact-crc:C3040575C63C69A9|rigid:Iu3MYsKsSKmQS3zrsuXCmq0qeY4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P19012	uniprotkb:Q02831	intact:EBI-739566|uniprotkb:Q53XV8|uniprotkb:Q9BUG4|uniprotkb:B3KQY1|uniprotkb:B3KRA2|uniprotkb:E0CX14|ensembl:ENSP00000254043|ensembl:ENSP00000377546	intact:EBI-31828|uniprotkb:D6W3T9|ensemblfungi:YPL077C	psi-mi:k1c15_human(display_long)|uniprotkb:KRT15(gene name)|psi-mi:KRT15(display_short)|uniprotkb:KRTB(gene name synonym)|uniprotkb:Cytokeratin-15(gene name synonym)|uniprotkb:Keratin-15(gene name synonym)	psi-mi:yp077_yeast(display_long)|uniprotkb:YPL077C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11534608|imex:IM-24995-1284	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002266.2|ensembl:ENSG00000171346(gene)|ensembl:ENST00000254043(transcript)|ensembl:ENST00000393976(transcript)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0008544"(epidermis development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097110"(scaffold protein binding)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR039008|mint:P19012|reactome:R-HSA-6805567|reactome:R-HSA-6809371|entrezgene/locuslink:3866(identity)	sgd:S000005998|refseq:NP_015248.1|dip:DIP-4022N|ensemblfungi:YPL077C(gene)|ensemblfungi:YPL077C_mRNA(transcript)|sgd:YPL077C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:WrZQBYQvrWcfrR5ojWXrXp6spPE9606	rogid:yqOn4GWKNmFZ7UvGmyBEpgoyKlA559292	intact-crc:40308956C0C49711|rigid:P9Ll3LXUd9uJ+1g3ix//cxWtTZM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P14373	uniprotkb:Q02831	intact:EBI-719493|uniprotkb:A2BE15|uniprotkb:Q5RJA8|uniprotkb:Q5ST26|uniprotkb:Q6LA73|uniprotkb:Q6NXR9|uniprotkb:Q9BZY6|uniprotkb:Q9UJL3|ensembl:ENSP00000383555|ensembl:ENSP00000392787|ensembl:ENSP00000405229|ensembl:ENSP00000414793|ensembl:ENSP00000366404	intact:EBI-31828|uniprotkb:D6W3T9|ensemblfungi:YPL077C	psi-mi:tri27_human(display_long)|uniprotkb:TRIM27(gene name)|psi-mi:TRIM27(display_short)|uniprotkb:RNF76(gene name synonym)|uniprotkb:RFP(gene name synonym)|uniprotkb:Ret finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 27(gene name synonym)|uniprotkb:RING finger protein 76(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM27(gene name synonym)	psi-mi:yp077_yeast(display_long)|uniprotkb:YPL077C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11534599|imex:IM-24995-1283	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006501.1|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0090281"(negative regulation of calcium ion import)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR020457|interpro:IPR035791|interpro:IPR043136|mint:P14373|reactome:R-HSA-3232142|reactome:R-HSA-9635465|reactome:R-HSA-8948751|ensembl:ENSG00000204713(gene)|ensembl:ENSG00000215641(gene)|ensembl:ENSG00000229006(gene)|ensembl:ENSG00000234495(gene)|ensembl:ENSG00000237071(gene)|ensembl:ENST00000377199(transcript)|ensembl:ENST00000400720(transcript)|ensembl:ENST00000431123(transcript)|ensembl:ENST00000435528(transcript)|ensembl:ENST00000437160(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001650"(fibrillar center)|go:"GO:0002820"(negative regulation of adaptive immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|entrezgene/locuslink:5987(identity)	sgd:S000005998|refseq:NP_015248.1|dip:DIP-4022N|ensemblfungi:YPL077C(gene)|ensemblfungi:YPL077C_mRNA(transcript)|sgd:YPL077C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:dsfH5OUghD8KSaTz1SFw9OYVTK49606	rogid:yqOn4GWKNmFZ7UvGmyBEpgoyKlA559292	intact-crc:1C2C2BDAD528AA89|rigid:Q8eGCfFM3ftJdYSF/cdD+C4spWQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q02831	uniprotkb:O95751	intact:EBI-31828|uniprotkb:D6W3T9|ensemblfungi:YPL077C	intact:EBI-740738|ensembl:ENSP00000359557|uniprotkb:Q6IAR6	psi-mi:yp077_yeast(display_long)|uniprotkb:YPL077C(locus name)	psi-mi:ldoc1_human(display_long)|uniprotkb:Leucine zipper protein down-regulated in cancer cells(gene name synonym)|uniprotkb:LDOC1(gene name)|psi-mi:LDOC1(display_short)|uniprotkb:BCUR1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11534590|imex:IM-24995-1282	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005998|refseq:NP_015248.1|dip:DIP-4022N|ensemblfungi:YPL077C(gene)|ensemblfungi:YPL077C_mRNA(transcript)|sgd:YPL077C(identity)	refseq:NP_036449.1|ensembl:ENSG00000182195(gene)|ensembl:ENST00000370526(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071225"(cellular response to muramyl dipeptide)|interpro:IPR032549|interpro:IPR032567|entrezgene/locuslink:23641(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:yqOn4GWKNmFZ7UvGmyBEpgoyKlA559292	rogid:Ediu0oNiZ/+YVY8l3fNdgP5A+v09606	intact-crc:E73E20DDBD3032E1|rigid:fHBBJNu1VoIgDlWXQtH3kp28p4c	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q02831	uniprotkb:Q7Z6G3-2	intact:EBI-31828|uniprotkb:D6W3T9|ensemblfungi:YPL077C	intact:EBI-10172876|ensembl:ENSP00000457354|intact:EBI-14062040	psi-mi:yp077_yeast(display_long)|uniprotkb:YPL077C(locus name)	psi-mi:q7z6g3-2(display_long)|uniprotkb:EFCBP2(gene name synonym)|uniprotkb:Neuronal calcium-binding protein 2(gene name synonym)|uniprotkb:Synaptotagmin-interacting protein 2(gene name synonym)|uniprotkb:NECAB2(gene name)|psi-mi:NECAB2(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11534579|imex:IM-24995-1281	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005998|refseq:NP_015248.1|dip:DIP-4022N|ensemblfungi:YPL077C(gene)|ensemblfungi:YPL077C_mRNA(transcript)|sgd:YPL077C(identity)	ensembl:ENSG00000103154(gene)|ensembl:ENST00000565691(transcript)|uniprotkb:Q7Z6G3-2(isoform-parent)|intact:EBI-950070(isoform-parent)|entrezgene/locuslink:54550(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:yqOn4GWKNmFZ7UvGmyBEpgoyKlA559292	rogid:4S7oIx6h+mKzV3EPxqcfMNqaNko9606	intact-crc:CFECA8469414D260|rigid:NS1rCXHrw1I2d8hIkI/N6uIQDic	false	-	sufficient binding region:65-303	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q02831	uniprotkb:Q9C0F1	intact:EBI-31828|uniprotkb:D6W3T9|ensemblfungi:YPL077C	intact:EBI-744115|uniprotkb:A8K8W9|uniprotkb:B3KT53|uniprotkb:Q8IXZ4|uniprotkb:A8MW11|uniprotkb:D3DP42|ensembl:ENSP00000296519|ensembl:ENSP00000380009|ensembl:ENSP00000423153	psi-mi:yp077_yeast(display_long)|uniprotkb:YPL077C(locus name)	psi-mi:cep44_human(display_long)|uniprotkb:HBV PreS1-transactivated protein 3(gene name synonym)|uniprotkb:CEP44(gene name)|psi-mi:CEP44(display_short)|uniprotkb:KIAA1712(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11534655|imex:IM-24995-1289	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005998|refseq:NP_015248.1|dip:DIP-4022N|ensemblfungi:YPL077C(gene)|ensemblfungi:YPL077C_mRNA(transcript)|sgd:YPL077C(identity)	refseq:NP_001035247.1|refseq:NP_001138786.1|refseq:XP_011530587.1|refseq:XP_011530588.1|refseq:XP_011530589.1|refseq:XP_016864143.1|refseq:XP_016864144.1|ensembl:ENSG00000164118(gene)|ensembl:ENST00000296519(transcript)|ensembl:ENST00000396791(transcript)|ensembl:ENST00000503780(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007099"(centriole replication)|go:"GO:0008017"(microtubule binding)|go:"GO:0010457"(centriole-centriole cohesion)|go:"GO:0030496"(midbody)|interpro:IPR029157|interpro:IPR033603|mint:Q9C0F1|entrezgene/locuslink:80817(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:yqOn4GWKNmFZ7UvGmyBEpgoyKlA559292	rogid:gDTC64oDhudGdsssC7v+suIHZkA9606	intact-crc:41CC587E235E341A|rigid:50Q2gyGzBzcnEF7jVh1IkGQULws	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q02831	uniprotkb:Q9BW62	intact:EBI-31828|uniprotkb:D6W3T9|ensemblfungi:YPL077C	intact:EBI-743591|uniprotkb:A8K5X4|ensembl:ENSP00000369989|ensembl:ENSP00000369991	psi-mi:yp077_yeast(display_long)|uniprotkb:YPL077C(locus name)	psi-mi:katl1_human(display_long)|uniprotkb:p60 katanin-like 1(gene name synonym)|uniprotkb:KATNAL1(gene name)|psi-mi:KATNAL1(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11534646|imex:IM-24995-1288	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005998|refseq:NP_015248.1|dip:DIP-4022N|ensemblfungi:YPL077C(gene)|ensemblfungi:YPL077C_mRNA(transcript)|sgd:YPL077C(identity)	refseq:NP_001014402.1|refseq:NP_115492.1|refseq:XP_005266631.1|ensembl:ENSG00000102781(gene)|ensembl:ENST00000380615(transcript)|ensembl:ENST00000380617(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005874"(microtubule)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008017"(microtubule binding)|go:"GO:0008568"(microtubule-severing ATPase activity)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016853"(isomerase activity)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0042802"(identical protein binding)|go:"GO:0051013"(microtubule severing)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR027417|interpro:IPR028594|interpro:IPR028596|interpro:IPR041569|rcsb pdb:6B5C|entrezgene/locuslink:84056(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:yqOn4GWKNmFZ7UvGmyBEpgoyKlA559292	rogid:Usi4KXsvZnNfMOGuWVSz4mfrTaE9606	intact-crc:15A5AC80A8CCD9AF|rigid:2q/MAHUgYzbqg3hSIr9fvteYX7Q	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q02831	uniprotkb:Q8N6Y0	intact:EBI-31828|uniprotkb:D6W3T9|ensemblfungi:YPL077C	intact:EBI-739895|uniprotkb:Q8NBX7|uniprotkb:Q96KH3|uniprotkb:Q9BYI8|uniprotkb:A8K7L6|uniprotkb:B2RCR9|ensembl:ENSP00000252597	psi-mi:yp077_yeast(display_long)|uniprotkb:YPL077C(locus name)	psi-mi:usbp1_human(display_long)|uniprotkb:USHBP1(gene name)|psi-mi:USHBP1(display_short)|uniprotkb:MCC-2(gene name synonym)|uniprotkb:AIE-75-binding protein(gene name synonym)|uniprotkb:AIEBP(gene name synonym)|uniprotkb:MCC2(gene name synonym)|uniprotkb:Mutated in colon cancer protein 2(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11534637|imex:IM-24995-1287	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005998|refseq:NP_015248.1|dip:DIP-4022N|ensemblfungi:YPL077C(gene)|ensemblfungi:YPL077C_mRNA(transcript)|sgd:YPL077C(identity)	refseq:NP_001284632.1|refseq:NP_114147.2|refseq:NP_001308346.1|ensembl:ENSG00000130307(gene)|ensembl:ENST00000252597(transcript)|go:"GO:0030165"(PDZ domain binding)|interpro:IPR019536|interpro:IPR040171|entrezgene/locuslink:83878(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:yqOn4GWKNmFZ7UvGmyBEpgoyKlA559292	rogid:vY1qx73Ju/z7WDu6k1kd10ZDVRo9606	intact-crc:03079F160D33FA27|rigid:A6DAO/TQOlWtb+Y+m+iQwuLfKpM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8IYF3-3	uniprotkb:Q02831	intact:EBI-11523345|ensembl:ENSP00000363453	intact:EBI-31828|uniprotkb:D6W3T9|ensemblfungi:YPL077C	psi-mi:q8iyf3-3(display_long)|uniprotkb:TEX11(gene name)|psi-mi:TEX11(display_short)|uniprotkb:Protein ZIP4 homolog(gene name synonym)|uniprotkb:ZIP4(gene name synonym)	psi-mi:yp077_yeast(display_long)|uniprotkb:YPL077C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11534626|imex:IM-24995-1286	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000120498(gene)|ensembl:ENST00000374333(transcript)|intact:EBI-742397(isoform-parent)|uniprotkb:Q8IYF3-3(isoform-parent)|entrezgene/locuslink:56159(identity)	sgd:S000005998|refseq:NP_015248.1|dip:DIP-4022N|ensemblfungi:YPL077C(gene)|ensemblfungi:YPL077C_mRNA(transcript)|sgd:YPL077C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:PUAMFmnm5ZV2rnJ1rhm9ZeRCixg9606	rogid:yqOn4GWKNmFZ7UvGmyBEpgoyKlA559292	intact-crc:8C50EAF6AF7CA0FC|rigid:yEHXFav+2oeLW097llC8xw/biz0	false	sufficient binding region:9-925	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q02872	uniprotkb:Q9NRF8	intact:EBI-38045|uniprotkb:D6W3Q9|ensemblfungi:YPL108W	intact:EBI-740874|ensembl:ENSP00000352222|ensembl:ENSP00000369590|ensembl:ENSP00000401264|uniprotkb:Q9BRI0|uniprotkb:Q9H809|uniprotkb:Q9H8K9|uniprotkb:B3KWM2	psi-mi:yp108_yeast(display_long)|uniprotkb:YPL108W(locus name)	psi-mi:pyrg2_human(display_long)|uniprotkb:UTP--ammonia ligase 2(gene name synonym)|uniprotkb:CTP synthetase 2(gene name synonym)|uniprotkb:CTPS2(gene name)|psi-mi:CTPS2(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11534673|imex:IM-24995-1291	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000006029|refseq:NP_015217.1|dip:DIP-5256N|ensemblfungi:YPL108W(gene)|ensemblfungi:YPL108W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|sgd:YPL108W(identity)	ensembl:ENSG00000047230(gene)|refseq:NP_001137474.1|refseq:NP_062831.3|refseq:NP_787055.1|ensembl:ENST00000359276(transcript)|ensembl:ENST00000380241(transcript)|ensembl:ENST00000443824(transcript)|go:"GO:0003883"(CTP synthase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006220"(pyrimidine nucleotide metabolic process)|go:"GO:0006241"(CTP biosynthetic process)|go:"GO:0006541"(glutamine metabolic process)|go:"GO:0019856"(pyrimidine nucleobase biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0044210"('de novo' CTP biosynthetic process)|go:"GO:0097268"(cytoophidium)|interpro:IPR004468(CTP synthase)|interpro:IPR017456(CTP synthase, N-terminal)|interpro:IPR017926|interpro:IPR027417|interpro:IPR029062|interpro:IPR033828|rcsb pdb:2V4U|rcsb pdb:2VKT|rcsb pdb:3IHL|rcsb pdb:6PK4|rcsb pdb:6PK7|reactome:R-HSA-499943|refseq:XP_006724566.1|refseq:XP_005274619.1|entrezgene/locuslink:56474(identity)	-	crc64:65A39A86CDA75D43	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:AzmIxOHHcaAoK/Paeo2aThOM2i8559292	rogid:BU/tvZTUS1d42+j0qSGAg7ND25Y9606	intact-crc:143AB338BE4F3CDA|rigid:W3tjJMSZcOCTqlcWwqXtIEyUQy8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UKT9	uniprotkb:Q02831	intact:EBI-747204|uniprotkb:Q8WWQ9|uniprotkb:Q8WWR0|uniprotkb:Q8WWR1|uniprotkb:Q8WWR2|uniprotkb:Q8WWR3|uniprotkb:Q8N574|uniprotkb:B4DVV5|uniprotkb:Q69BL6|uniprotkb:Q69BL7|uniprotkb:Q69BL8|uniprotkb:Q69BL9|uniprotkb:Q69BM0|uniprotkb:Q69BM1|uniprotkb:Q69BM2|uniprotkb:Q69BM3|uniprotkb:Q69BM5|ensembl:ENSP00000344544	intact:EBI-31828|uniprotkb:D6W3T9|ensemblfungi:YPL077C	psi-mi:ikzf3_human(display_long)|uniprotkb:ZNFN1A3(gene name synonym)|uniprotkb:Ikaros family zinc finger protein 3(gene name synonym)|uniprotkb:IKZF3(gene name)|psi-mi:IKZF3(display_short)	psi-mi:yp077_yeast(display_long)|uniprotkb:YPL077C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11534664|imex:IM-24995-1290	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001271443.1|refseq:NP_001271444.1|refseq:NP_036613.2|refseq:NP_899051.1|refseq:NP_899052.1|refseq:NP_899053.1|refseq:NP_899054.1|refseq:NP_899055.1|refseq:NP_001271445.1|refseq:NP_001244337.1|refseq:NP_001244338.1|refseq:NP_001244339.1|refseq:NP_001244340.1|refseq:NP_001244341.1|refseq:NP_001244342.1|refseq:NP_001244343.1|ensembl:ENSG00000161405(gene)|ensembl:ENST00000346872(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007498"(mesoderm development)|go:"GO:0009617"(response to bacterium)|go:"GO:0030888"(regulation of B cell proliferation)|go:"GO:0042113"(B cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045577"(regulation of B cell differentiation)|go:"GO:0045619"(regulation of lymphocyte differentiation)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|go:"GO:0046872"(metal ion binding)|dip:DIP-56975N|entrezgene/locuslink:22806(identity)	sgd:S000005998|refseq:NP_015248.1|dip:DIP-4022N|ensemblfungi:YPL077C(gene)|ensemblfungi:YPL077C_mRNA(transcript)|sgd:YPL077C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:2Kp6LefSLfK5VIiE6DmQusFIfMY9606	rogid:yqOn4GWKNmFZ7UvGmyBEpgoyKlA559292	intact-crc:6B37A02E5C5E135A|rigid:oScBJtu7xWOjgUIb5f5LQdYTiGI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P19012	uniprotkb:Q03020	intact:EBI-739566|uniprotkb:Q53XV8|uniprotkb:Q9BUG4|uniprotkb:B3KQY1|uniprotkb:B3KRA2|uniprotkb:E0CX14|ensembl:ENSP00000254043|ensembl:ENSP00000377546	intact:EBI-29901|uniprotkb:D6W3N2|ensemblfungi:YPL135W	psi-mi:k1c15_human(display_long)|uniprotkb:KRT15(gene name)|psi-mi:KRT15(display_short)|uniprotkb:KRTB(gene name synonym)|uniprotkb:Cytokeratin-15(gene name synonym)|uniprotkb:Keratin-15(gene name synonym)	psi-mi:isu1_yeast(display_long)|uniprotkb:YPL135W(locus name)|uniprotkb:Iron sulfur cluster scaffold protein 1(gene name synonym)|uniprotkb:ISU1(gene name)|psi-mi:ISU1(display_short)|uniprotkb:NUA1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11534702|imex:IM-24995-1294	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002266.2|ensembl:ENSG00000171346(gene)|ensembl:ENST00000254043(transcript)|ensembl:ENST00000393976(transcript)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0008544"(epidermis development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097110"(scaffold protein binding)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR039008|mint:P19012|reactome:R-HSA-6805567|reactome:R-HSA-6809371|entrezgene/locuslink:3866(identity)	refseq:NP_015190.1|sgd:S000006056|dip:DIP-6556N|mint:Q03020|ensemblfungi:YPL135W(gene)|ensemblfungi:YPL135W_mRNA(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005506"(iron ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR002871(NIF system FeS cluster assembly, NifU, N-terminal)|interpro:IPR011339(ISC system FeS cluster assembly, IscU scaffold)|rcsb pdb:5T0V|rcsb pdb:5TRE|reactome:R-SCE-1362409|sgd:YPL135W(identity)	-	-	crc64:E240845A27D2E9EE	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:WrZQBYQvrWcfrR5ojWXrXp6spPE9606	rogid:zpPseOgZoK3cF+mCetzw05ct9Kc559292	intact-crc:0407A565C1D9D180|rigid:v0AqN/Dy/CE4nd/2PzCo5gJ90m4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q03020	uniprotkb:P12268	intact:EBI-29901|uniprotkb:D6W3N2|ensemblfungi:YPL135W	intact:EBI-353389|uniprotkb:Q6LEF3|ensembl:ENSP00000321584	psi-mi:isu1_yeast(display_long)|uniprotkb:YPL135W(locus name)|uniprotkb:Iron sulfur cluster scaffold protein 1(gene name synonym)|uniprotkb:ISU1(gene name)|psi-mi:ISU1(display_short)|uniprotkb:NUA1(gene name synonym)	psi-mi:imdh2_human(display_long)|uniprotkb:IMPDH2(gene name)|psi-mi:IMPDH2(display_short)|uniprotkb:IMPD2(gene name synonym)|uniprotkb:Inosine-5'-monophosphate dehydrogenase type II(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11534693|imex:IM-24995-1293	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015190.1|sgd:S000006056|dip:DIP-6556N|mint:Q03020|ensemblfungi:YPL135W(gene)|ensemblfungi:YPL135W_mRNA(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005506"(iron ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR002871(NIF system FeS cluster assembly, NifU, N-terminal)|interpro:IPR011339(ISC system FeS cluster assembly, IscU scaffold)|rcsb pdb:5T0V|rcsb pdb:5TRE|reactome:R-SCE-1362409|sgd:YPL135W(identity)	refseq:NP_000875.2|ensembl:ENSG00000178035(gene)|ensembl:ENST00000326739(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003938"(IMP dehydrogenase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006177"(GMP biosynthetic process)|go:"GO:0006183"(GTP biosynthetic process)|go:"GO:0007623"(circadian rhythm)|go:"GO:0016020"(membrane)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042802"(identical protein binding)|go:"GO:0046651"(lymphocyte proliferation)|go:"GO:0046872"(metal ion binding)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR001093(IMP dehydrogenase/GMP reductase)|interpro:IPR005990(IMP dehydrogenase)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR015875(IMP dehydrogenase / GMP reductase, conserved site)|mint:P12268|rcsb pdb:1B3O|rcsb pdb:1NF7|rcsb pdb:1NFB|rcsb pdb:6I0M|rcsb pdb:6I0O|rcsb pdb:6U8E|rcsb pdb:6U8N|rcsb pdb:6U8R|rcsb pdb:6U8S|rcsb pdb:6U9O|rcsb pdb:6UA2|rcsb pdb:6UA4|rcsb pdb:6UA5|rcsb pdb:6UAJ|rcsb pdb:6UC2|rcsb pdb:6UDO|rcsb pdb:6UDP|rcsb pdb:6UDQ|reactome:R-HSA-6798695|reactome:R-HSA-73817|reactome:R-HSA-9679191|entrezgene/locuslink:3615(identity)	-	crc64:E240845A27D2E9EE	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:zpPseOgZoK3cF+mCetzw05ct9Kc559292	rogid:qGPwBxhEgtYik3OetHZbpyktoLE9606	intact-crc:55E27D35A06F04A8|rigid:UUS0JBOozVlfgyupMRQItfMqcVw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:E9PFK9	uniprotkb:Q02939	intact:EBI-11523104|ensembl:ENSP00000403429	intact:EBI-2345544|uniprotkb:D6W3P5|uniprotkb:P87331|ensemblfungi:YPL122C	psi-mi:e9pfk9_human(display_long)|uniprotkb:RABGEF1(gene name)|psi-mi:RABGEF1(display_short)	psi-mi:tfb2_yeast(display_long)|uniprotkb:RNA polymerase II transcription factor B subunit 2(gene name synonym)|uniprotkb:YPL122C(locus name)|uniprotkb:TFB2(gene name)|psi-mi:TFB2(display_short)|uniprotkb:RNA polymerase II transcription factor B p52 subunit(gene name synonym)|uniprotkb:RNA polymerase II transcription factor B 52 kDa subunit(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11534682|imex:IM-24995-1292	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000154710(gene)|ensembl:ENST00000439720(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|interpro:IPR002653(Zinc finger, A20-type)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR037191|interpro:IPR041545|entrezgene/locuslink:27342(identity)	refseq:NP_015203.1|sgd:S000006043|dip:DIP-5783N|mint:Q02939|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-5696395|reactome:R-SCE-674695|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-72086|reactome:R-SCE-73772|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075|ensemblfungi:YPL122C(gene)|ensemblfungi:YPL122C_mRNA(transcript)|go:"GO:0000112"(nucleotide-excision repair factor 3 complex)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR004598(Transcription factor Tfb2)|interpro:IPR040662|rcsb pdb:3DGP|rcsb pdb:3DOM|rcsb pdb:5FMF|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:5SVA|rcsb pdb:6GYM|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O4K|rcsb pdb:7O4L|rcsb pdb:7O72|rcsb pdb:7O73|sgd:YPL122C(identity)	-	-	crc64:9E440B566396A95A	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:JDHW8cuCB2z39j6a+LlkARnLfYo9606	rogid:TJC5kOBM7mOJLttEEiSqXvlVyXc559292	intact-crc:714B9E7F84EFD40E|rigid:Q8lrt3YrZkk3lWQRn1kFPM2jTyE	false	sufficient binding region:14-504	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9Y3Q8	uniprotkb:Q03020	intact:EBI-739485|uniprotkb:A8MWR6|ensembl:ENSP00000300181|uniprotkb:A4D2C3|uniprotkb:D6W5V9	intact:EBI-29901|uniprotkb:D6W3N2|ensemblfungi:YPL135W	psi-mi:t22d4_human(display_long)|uniprotkb:TSC22D4(gene name)|psi-mi:TSC22D4(display_short)|uniprotkb:TILZ2(gene name synonym)|uniprotkb:TSC22-related-inducible leucine zipper protein 2(gene name synonym)|uniprotkb:Tsc-22-like protein THG-1(gene name synonym)|uniprotkb:THG1(gene name synonym)	psi-mi:isu1_yeast(display_long)|uniprotkb:YPL135W(locus name)|uniprotkb:Iron sulfur cluster scaffold protein 1(gene name synonym)|uniprotkb:ISU1(gene name)|psi-mi:ISU1(display_short)|uniprotkb:NUA1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11534747|imex:IM-24995-1299	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000166925(gene)|ensembl:ENST00000300181(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006970"(response to osmotic stress)|interpro:IPR000580(TSC-22 / Dip / Bun)|interpro:IPR042553|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|refseq:NP_112197.1|refseq:NP_001289972.1|entrezgene/locuslink:81628(identity)	refseq:NP_015190.1|sgd:S000006056|dip:DIP-6556N|mint:Q03020|ensemblfungi:YPL135W(gene)|ensemblfungi:YPL135W_mRNA(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005506"(iron ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR002871(NIF system FeS cluster assembly, NifU, N-terminal)|interpro:IPR011339(ISC system FeS cluster assembly, IscU scaffold)|rcsb pdb:5T0V|rcsb pdb:5TRE|reactome:R-SCE-1362409|sgd:YPL135W(identity)	-	-	crc64:E240845A27D2E9EE	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:eL12cHY76zEPOXzT1HFKPSckS8Y9606	rogid:zpPseOgZoK3cF+mCetzw05ct9Kc559292	intact-crc:BFA81D8838B378BD|rigid:7/fk/v7+VK0rnscXpMwupZD/a2Y	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q03020	uniprotkb:Q969J2	intact:EBI-29901|uniprotkb:D6W3N2|ensemblfungi:YPL135W	intact:EBI-2818641|uniprotkb:B2RE32|uniprotkb:Q5U7L4|intact:EBI-28979011|ensembl:ENSP00000366509	psi-mi:isu1_yeast(display_long)|uniprotkb:YPL135W(locus name)|uniprotkb:Iron sulfur cluster scaffold protein 1(gene name synonym)|uniprotkb:ISU1(gene name)|psi-mi:ISU1(display_short)|uniprotkb:NUA1(gene name synonym)	psi-mi:zksc4_human(display_long)|uniprotkb:ZKSCAN4(gene name)|psi-mi:ZKSCAN4(display_short)|uniprotkb:ZNF307(gene name synonym)|uniprotkb:ZNF427(gene name synonym)|uniprotkb:P373c6.1(gene name synonym)|uniprotkb:Zinc finger protein 307(gene name synonym)|uniprotkb:Zinc finger protein 427(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11534738|imex:IM-24995-1298	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015190.1|sgd:S000006056|dip:DIP-6556N|mint:Q03020|ensemblfungi:YPL135W(gene)|ensemblfungi:YPL135W_mRNA(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005506"(iron ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR002871(NIF system FeS cluster assembly, NifU, N-terminal)|interpro:IPR011339(ISC system FeS cluster assembly, IscU scaffold)|rcsb pdb:5T0V|rcsb pdb:5TRE|reactome:R-SCE-1362409|sgd:YPL135W(identity)	refseq:NP_061983.2|ensembl:ENSP00000366509|ensembl:ENSG00000187626(gene)|ensembl:ENST00000377294(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|interpro:IPR038269|mint:Q969J2|reactome:R-HSA-212436|refseq:XP_005249152.1|entrezgene/locuslink:387032(identity)	-	crc64:E240845A27D2E9EE	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:zpPseOgZoK3cF+mCetzw05ct9Kc559292	rogid:5TWhAtzfmCXHkOSbjKwjgLIsCcs9606	intact-crc:B848D8BB30D25C6C|rigid:oyK6B/NIQxzojwQvcUz5rhG6Ilw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q93062-3	uniprotkb:Q03020	intact:EBI-740343|ensembl:ENSP00000340176	intact:EBI-29901|uniprotkb:D6W3N2|ensemblfungi:YPL135W	psi-mi:q93062-3(display_long)|uniprotkb:RBPMS(gene name)|psi-mi:RBPMS(display_short)|uniprotkb:HERMES(gene name synonym)|uniprotkb:Heart and RRM expressed sequence(gene name synonym)	psi-mi:isu1_yeast(display_long)|uniprotkb:YPL135W(locus name)|uniprotkb:Iron sulfur cluster scaffold protein 1(gene name synonym)|uniprotkb:ISU1(gene name)|psi-mi:ISU1(display_short)|uniprotkb:NUA1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11534729|imex:IM-24995-1297	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-740322(rbpms_human)|uniprotkb:Q93062-3(isoform-parent)|ensembl:ENSG00000157110(gene)|ensembl:ENST00000339877(transcript)|entrezgene/locuslink:11030(identity)	refseq:NP_015190.1|sgd:S000006056|dip:DIP-6556N|mint:Q03020|ensemblfungi:YPL135W(gene)|ensemblfungi:YPL135W_mRNA(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005506"(iron ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR002871(NIF system FeS cluster assembly, NifU, N-terminal)|interpro:IPR011339(ISC system FeS cluster assembly, IscU scaffold)|rcsb pdb:5T0V|rcsb pdb:5TRE|reactome:R-SCE-1362409|sgd:YPL135W(identity)	-	-	crc64:E240845A27D2E9EE	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:nlPMQAJoKEbPYBwsL3xodmCKd7c9606	rogid:zpPseOgZoK3cF+mCetzw05ct9Kc559292	intact-crc:DBE4AF71FAF985ED|rigid:p2Ku2KyhTX79IL6qo7CX0bDyGDc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q13643	uniprotkb:Q03020	intact:EBI-741101|ensembl:ENSP00000362107|uniprotkb:Q6I9T0|uniprotkb:Q9BVA2|uniprotkb:D3DPT6	intact:EBI-29901|uniprotkb:D6W3N2|ensemblfungi:YPL135W	psi-mi:fhl3_human(display_long)|uniprotkb:FHL3(gene name)|psi-mi:FHL3(display_short)|uniprotkb:SLIM2(gene name synonym)|uniprotkb:Skeletal muscle LIM-protein 2(gene name synonym)	psi-mi:isu1_yeast(display_long)|uniprotkb:YPL135W(locus name)|uniprotkb:Iron sulfur cluster scaffold protein 1(gene name synonym)|uniprotkb:ISU1(gene name)|psi-mi:ISU1(display_short)|uniprotkb:NUA1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11534720|imex:IM-24995-1296	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004459.2|ensembl:ENSG00000183386(gene)|ensembl:ENST00000373016(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005925"(focal adhesion)|go:"GO:0007517"(muscle organ development)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0046872"(metal ion binding)|interpro:IPR001781(Zinc finger, LIM-type)|mint:Q13643|rcsb pdb:1WYH|rcsb pdb:2CUQ|rcsb pdb:2EHE|interpro:IPR037987|refseq:NP_001230807.1|dip:DIP-42030N|entrezgene/locuslink:2275(identity)	refseq:NP_015190.1|sgd:S000006056|dip:DIP-6556N|mint:Q03020|ensemblfungi:YPL135W(gene)|ensemblfungi:YPL135W_mRNA(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005506"(iron ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR002871(NIF system FeS cluster assembly, NifU, N-terminal)|interpro:IPR011339(ISC system FeS cluster assembly, IscU scaffold)|rcsb pdb:5T0V|rcsb pdb:5TRE|reactome:R-SCE-1362409|sgd:YPL135W(identity)	-	-	crc64:E240845A27D2E9EE	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:RAo+b/VgFSnHSbgR+zXuxJvypxM9606	rogid:zpPseOgZoK3cF+mCetzw05ct9Kc559292	intact-crc:B72321467C0B2CF1|rigid:7JjiiY117RFpQJOaWkGL36p7ibY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P61289	uniprotkb:Q03020	intact:EBI-355546|uniprotkb:O35563|uniprotkb:P97373|uniprotkb:Q12920|uniprotkb:Q13172|uniprotkb:Q9BQD9|uniprotkb:A8K9A3|ensembl:ENSP00000466794	intact:EBI-29901|uniprotkb:D6W3N2|ensemblfungi:YPL135W	psi-mi:psme3_human(display_long)|uniprotkb:PSME3(gene name)|psi-mi:PSME3(display_short)|uniprotkb:Proteasome activator 28 subunit gamma(gene name synonym)|uniprotkb:Activator of multicatalytic protease subunit 3(gene name synonym)|uniprotkb:11S regulator complex subunit gamma(gene name synonym)|uniprotkb:Ki nuclear autoantigen(gene name synonym)	psi-mi:isu1_yeast(display_long)|uniprotkb:YPL135W(locus name)|uniprotkb:Iron sulfur cluster scaffold protein 1(gene name synonym)|uniprotkb:ISU1(gene name)|psi-mi:ISU1(display_short)|uniprotkb:NUA1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11534711|imex:IM-24995-1295	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005780.2|refseq:NP_789839.1|ensembl:ENSG00000131467(gene)|ensembl:ENST00000590720(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0008537"(proteasome activator complex)|go:"GO:0010950"(positive regulation of endopeptidase activity)|go:"GO:0016020"(membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0061133"(endopeptidase activator activity)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0097371"(MDM2/MDM4 family protein binding)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR003185(Proteasome activator pa28, REG alpha subunit)|interpro:IPR003186(Proteasome activator pa28, REG beta subunit)|interpro:IPR009077(Proteasome activator pa28, REG alpha/beta subunit)|interpro:IPR036252|interpro:IPR036996|interpro:IPR036997|mint:P61289|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|entrezgene/locuslink:10197(identity)	refseq:NP_015190.1|sgd:S000006056|dip:DIP-6556N|mint:Q03020|ensemblfungi:YPL135W(gene)|ensemblfungi:YPL135W_mRNA(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005506"(iron ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR002871(NIF system FeS cluster assembly, NifU, N-terminal)|interpro:IPR011339(ISC system FeS cluster assembly, IscU scaffold)|rcsb pdb:5T0V|rcsb pdb:5TRE|reactome:R-SCE-1362409|sgd:YPL135W(identity)	-	-	crc64:E240845A27D2E9EE	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:6EQY2Kj3Juf++m4eBDzPWMgbC2k9606	rogid:zpPseOgZoK3cF+mCetzw05ct9Kc559292	intact-crc:73AE905E4FA2C864|rigid:dQyLm0cBx4VWs2S9MCLhvoIl1/4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O43809	uniprotkb:Q03262	intact:EBI-355720|uniprotkb:Q6IB85|uniprotkb:Q6NE84|ensembl:ENSP00000300291	intact:EBI-27609|uniprotkb:D6W0A5|ensemblfungi:YMR278W	psi-mi:cpsf5_human(display_long)|uniprotkb:NUDT21(gene name)|psi-mi:NUDT21(display_short)|uniprotkb:CFIM25(gene name synonym)|uniprotkb:CPSF25(gene name synonym)|uniprotkb:CPSF5(gene name synonym)|uniprotkb:Cleavage and polyadenylation specificity factor 25 kDa subunit(gene name synonym)|uniprotkb:Nucleoside diphosphate-linked moiety X motif 21(gene name synonym)|uniprotkb:Cleavage factor Im complex 25 kDa subunit(gene name synonym)|uniprotkb:Nudix hydrolase 21(gene name synonym)|uniprotkb:Pre-mRNA cleavage factor Im 68 kDa subunit(gene name synonym)	psi-mi:pgm3_yeast(display_long)|uniprotkb:PRM15(gene name)|psi-mi:PRM15(display_short)|uniprotkb:PGM3(gene name synonym)|uniprotkb:Phosphoglucomutase 3(gene name synonym)|uniprotkb:YM8021.04(orf name)|uniprotkb:YMR278W(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11534793|imex:IM-24995-1304	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_008937.1|ensembl:ENSG00000167005(gene)|ensembl:ENST00000300291(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0005849"(mRNA cleavage factor complex)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0006397"(mRNA processing)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0031439"(positive regulation of mRNA cleavage)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0042382"(paraspeckles)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051290"(protein heterotetramerization)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|go:"GO:0110104"(mRNA alternative polyadenylation)|go:"GO:1900365"(positive regulation of mRNA polyadenylation)|go:"GO:1990120"(messenger ribonucleoprotein complex assembly)|go:"GO:2000738"(positive regulation of stem cell differentiation)|go:"GO:2000975"(positive regulation of pro-B cell differentiation)|interpro:IPR000086(NUDIX hydrolase, core)|interpro:IPR015797(NUDIX)|interpro:IPR016706(Cleavage and polyadenylation specificity factor, 25 kDa subunit)|mint:O43809|rcsb pdb:2CL3|rcsb pdb:2J8Q|rcsb pdb:3BAP|rcsb pdb:3BHO|rcsb pdb:3MDG|rcsb pdb:3MDI|rcsb pdb:3N9U|rcsb pdb:3P5T|rcsb pdb:3P6Y|rcsb pdb:3Q2S|rcsb pdb:3Q2T|rcsb pdb:5R4P|rcsb pdb:5R4Q|rcsb pdb:5R4R|rcsb pdb:5R4S|rcsb pdb:5R4T|rcsb pdb:5R4U|rcsb pdb:5R64|rcsb pdb:5R65|rcsb pdb:5R66|rcsb pdb:5R67|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-77595|dip:DIP-42502N|entrezgene/locuslink:11051(identity)	sgd:S000004891|refseq:NP_014005.1|reactome:R-SCE-3322077|reactome:R-SCE-71336|reactome:R-SCE-6798695|dip:DIP-5066N|reactome:R-SCE-70171|reactome:R-SCE-70221|reactome:R-SCE-70370|interpro:IPR036900|interpro:IPR016066(Alpha-D-phosphohexomutase, conserved site)|ensemblfungi:YMR278W(gene)|ensemblfungi:YMR278W_mRNA(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006148"(inosine catabolic process)|go:"GO:0006166"(purine ribonucleoside salvage)|go:"GO:0008973"(phosphopentomutase activity)|go:"GO:0046115"(guanosine catabolic process)|interpro:IPR005843(Alpha-D-phosphohexomutase, C-terminal)|interpro:IPR005844(Alpha-D-phosphohexomutase, alpha/beta/alpha domain I)|interpro:IPR005845(Alpha-D-phosphohexomutase, alpha/beta/alpha domain II)|interpro:IPR005846(Alpha-D-phosphohexomutase, alpha/beta/alpha domain III)|interpro:IPR016055(Alpha-D-phosphohexomutase, alpha/beta/alpha I, II and III)|sgd:YMR278W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Acad4mYVuS+Eox+X2CH8PYUkGAA9606	rogid:hEeb0XLedLqmf04ufZaiMNcwQXE559292	intact-crc:9F6527FE889272AC|rigid:XWdqPBSj+MwrHkF4/LloWEX52fE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q13422-7	uniprotkb:Q03233	intact:EBI-11522367|ensembl:ENSP00000352123|ensembl:ENSP00000413025	intact:EBI-27402|uniprotkb:D6W008|ensemblfungi:YMR184W	psi-mi:q13422-7(display_long)|uniprotkb:IKZF1(gene name)|psi-mi:IKZF1(display_short)|uniprotkb:IK1(gene name synonym)|uniprotkb:IKAROS(gene name synonym)|uniprotkb:Ikaros family zinc finger protein 1(gene name synonym)|uniprotkb:LYF1(gene name synonym)|uniprotkb:Lymphoid transcription factor LyF-1(gene name synonym)|uniprotkb:ZNFN1A1(gene name synonym)	psi-mi:add37_yeast(display_long)|uniprotkb:YM8010.14(orf name)|uniprotkb:YMR184W(locus name)|uniprotkb:ADD37(gene name)|psi-mi:ADD37(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11534784|imex:IM-24995-1303	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-745305(isoform-parent)|ensembl:ENSG00000185811(gene)|ensembl:ENST00000359197(transcript)|ensembl:ENST00000439701(transcript)|uniprotkb:Q13422-7(isoform-parent)|entrezgene/locuslink:10320(identity)	sgd:S000004796|refseq:NP_013909.1|dip:DIP-3848N|ensemblfungi:YMR184W(gene)|ensemblfungi:YMR184W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|sgd:YMR184W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:ou/ovXYoMneBNVp4pj38VxenfyY9606	rogid:1f4WwSzzLoaYs7mq9XrVap58RWE559292	intact-crc:9D91FDF65E7DEDA3|rigid:Q741FjeixosXKGt7X2veqa1bpo0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q03063	uniprotkb:P63279	intact:EBI-29752|uniprotkb:D6W3W5|ensemblfungi:YPL049C	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	psi-mi:dig1_yeast(display_long)|uniprotkb:DIG1(gene name)|psi-mi:DIG1(display_short)|uniprotkb:Regulator of sterile twelve 1(gene name synonym)|uniprotkb:Regulator of STE12 protein 1(gene name synonym)|uniprotkb:RST1(gene name synonym)|uniprotkb:P7102.02(orf name)|uniprotkb:YPL049C(locus name)	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11534775|imex:IM-24995-1302	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005970|refseq:NP_015276.1|dip:DIP-1291N|mint:Q03063|ensemblfungi:YPL049C(gene)|ensemblfungi:YPL049C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0008134"(transcription factor binding)|go:"GO:0046020"(negative regulation of transcription from RNA polymerase II promoter by pheromones)|go:"GO:1900240"(negative regulation of phenotypic switching)|go:"GO:1990526"(Ste12p-Dig1p-Dig2p complex)|go:"GO:1990527"(Tec1p-Ste12p-Dig1p complex)|go:"GO:2000218"(negative regulation of invasive growth in response to glucose limitation)|go:"GO:2000221"(negative regulation of pseudohyphal growth)|sgd:YPL049C(identity)	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N|entrezgene/locuslink:7329(identity)	-	crc64:2D27F9878BFADD30	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Qt+hpsHdt+kIqMB+GKG4AYKLgOQ559292	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	intact-crc:C6B7AFD6563FDE71|rigid:Umtwr71MyQ/+i5yADc7EBy2nXJs	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q03063	uniprotkb:P23497-2	intact:EBI-29752|uniprotkb:D6W3W5|ensemblfungi:YPL049C	intact:EBI-6589365|ensembl:ENSP00000386404	psi-mi:dig1_yeast(display_long)|uniprotkb:DIG1(gene name)|psi-mi:DIG1(display_short)|uniprotkb:Regulator of sterile twelve 1(gene name synonym)|uniprotkb:Regulator of STE12 protein 1(gene name synonym)|uniprotkb:RST1(gene name synonym)|uniprotkb:P7102.02(orf name)|uniprotkb:YPL049C(locus name)	psi-mi:p23497-2(display_long)|uniprotkb:SP100(isoform synonym)|uniprotkb:SP100(gene name)|psi-mi:SP100(display_short)|uniprotkb:Nuclear dot-associated Sp100 protein(gene name synonym)|uniprotkb:Speckled 100 kDa(gene name synonym)|uniprotkb:SP100A(isoform synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11534766|imex:IM-24995-1301	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005970|refseq:NP_015276.1|dip:DIP-1291N|mint:Q03063|ensemblfungi:YPL049C(gene)|ensemblfungi:YPL049C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0008134"(transcription factor binding)|go:"GO:0046020"(negative regulation of transcription from RNA polymerase II promoter by pheromones)|go:"GO:1900240"(negative regulation of phenotypic switching)|go:"GO:1990526"(Ste12p-Dig1p-Dig2p complex)|go:"GO:1990527"(Tec1p-Ste12p-Dig1p complex)|go:"GO:2000218"(negative regulation of invasive growth in response to glucose limitation)|go:"GO:2000221"(negative regulation of pseudohyphal growth)|sgd:YPL049C(identity)	intact:EBI-751145(isoform-parent)|uniprotkb:P23497-2(isoform-parent)|ensembl:ENSG00000067066(gene)|ensembl:ENST00000409341(transcript)|entrezgene/locuslink:6672(identity)	-	crc64:2D27F9878BFADD30	isoform-comment:Major isoform.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Qt+hpsHdt+kIqMB+GKG4AYKLgOQ559292	rogid:HrcogLANB///4vkSYtZ7OtzOb2k9606	intact-crc:707F2B9D8A7D0851|rigid:gd24i9x60yUV9LMH26ANwDUHUoo	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q03063	uniprotkb:O14641	intact:EBI-29752|uniprotkb:D6W3W5|ensemblfungi:YPL049C	intact:EBI-740850|ensembl:ENSP00000005340|uniprotkb:Q53XM0|uniprotkb:D3DTN3	psi-mi:dig1_yeast(display_long)|uniprotkb:DIG1(gene name)|psi-mi:DIG1(display_short)|uniprotkb:Regulator of sterile twelve 1(gene name synonym)|uniprotkb:Regulator of STE12 protein 1(gene name synonym)|uniprotkb:RST1(gene name synonym)|uniprotkb:P7102.02(orf name)|uniprotkb:YPL049C(locus name)	psi-mi:dvl2_human(display_long)|uniprotkb:DSH homolog 2(gene name synonym)|uniprotkb:DVL2(gene name)|psi-mi:DVL2(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11534757|imex:IM-24995-1300	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005970|refseq:NP_015276.1|dip:DIP-1291N|mint:Q03063|ensemblfungi:YPL049C(gene)|ensemblfungi:YPL049C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0008134"(transcription factor binding)|go:"GO:0046020"(negative regulation of transcription from RNA polymerase II promoter by pheromones)|go:"GO:1900240"(negative regulation of phenotypic switching)|go:"GO:1990526"(Ste12p-Dig1p-Dig2p complex)|go:"GO:1990527"(Tec1p-Ste12p-Dig1p complex)|go:"GO:2000218"(negative regulation of invasive growth in response to glucose limitation)|go:"GO:2000221"(negative regulation of pseudohyphal growth)|sgd:YPL049C(identity)	refseq:NP_004413.1|ensembl:ENSG00000004975(gene)|ensembl:ENST00000005340(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005109"(frizzled binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0007507"(heart development)|go:"GO:0016235"(aggresome)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044340"(canonical Wnt signaling pathway involved in regulation of cell proliferation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0150012"(positive regulation of neuron projection arborization)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008341(Dishevelled-2 region)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:O14641|rcsb pdb:2REY|rcsb pdb:3CBX|rcsb pdb:3CBY|rcsb pdb:3CBZ|rcsb pdb:3CC0|rcsb pdb:4WIP|rcsb pdb:5LNP|rcsb pdb:5SUY|rcsb pdb:5SUZ|rcsb pdb:6IW3|rcsb pdb:6JCK|reactome:R-HSA-201681|reactome:R-HSA-201688|reactome:R-HSA-2028269|reactome:R-HSA-4086400|reactome:R-HSA-4608870|reactome:R-HSA-4641258|reactome:R-HSA-4641262|reactome:R-HSA-5099900|reactome:R-HSA-5368598|reactome:R-HSA-5663220|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9673324|ensembl:ENSP00000005340|dip:DIP-34433N|entrezgene/locuslink:1856(identity)	-	crc64:2D27F9878BFADD30	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Qt+hpsHdt+kIqMB+GKG4AYKLgOQ559292	rogid:2Vdc8oRnT4Mz/j+EXQXrL3AszOc9606	intact-crc:6B67186885C19D8F|rigid:/wBHfqjPn6GO0FbXwA2Su0E5RvM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9C0F1	uniprotkb:Q03338	intact:EBI-744115|uniprotkb:A8K8W9|uniprotkb:B3KT53|uniprotkb:Q8IXZ4|uniprotkb:A8MW11|uniprotkb:D3DP42|ensembl:ENSP00000296519|ensembl:ENSP00000380009|ensembl:ENSP00000423153	intact:EBI-421|uniprotkb:D6VT97|ensemblfungi:YDR473C	psi-mi:cep44_human(display_long)|uniprotkb:HBV PreS1-transactivated protein 3(gene name synonym)|uniprotkb:CEP44(gene name)|psi-mi:CEP44(display_short)|uniprotkb:KIAA1712(gene name synonym)	psi-mi:prp3_yeast(display_long)|uniprotkb:PRP3(gene name)|psi-mi:PRP3(display_short)|uniprotkb:RNA3(gene name synonym)|uniprotkb:YDR473C(locus name)|uniprotkb:D8035.16(orf name)|uniprotkb:Pre-mRNA-splicing factor 3(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11534838|imex:IM-24995-1309	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001035247.1|refseq:NP_001138786.1|refseq:XP_011530587.1|refseq:XP_011530588.1|refseq:XP_011530589.1|refseq:XP_016864143.1|refseq:XP_016864144.1|ensembl:ENSG00000164118(gene)|ensembl:ENST00000296519(transcript)|ensembl:ENST00000396791(transcript)|ensembl:ENST00000503780(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007099"(centriole replication)|go:"GO:0008017"(microtubule binding)|go:"GO:0010457"(centriole-centriole cohesion)|go:"GO:0030496"(midbody)|interpro:IPR029157|interpro:IPR033603|mint:Q9C0F1|entrezgene/locuslink:80817(identity)	sgd:S000002881|refseq:NP_010761.3|ensemblfungi:YDR473C(gene)|ensemblfungi:YDR473C_mRNA(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|interpro:IPR010541(Protein of unknown function DUF1115)|interpro:IPR013881(Pre-mRNA-splicing factor 3)|interpro:IPR027104|rcsb pdb:3JCM|rcsb pdb:4YHU|rcsb pdb:4YHV|rcsb pdb:4YHW|rcsb pdb:5GAN|rcsb pdb:5GAP|rcsb pdb:5NRL|rcsb pdb:5ZWM|rcsb pdb:5ZWO|dip:DIP-5266N|mint:Q03338|sgd:YDR473C(identity)	-	-	crc64:E977FD9F708BDD91	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:gDTC64oDhudGdsssC7v+suIHZkA9606	rogid:KE0Y/kRXTq9LXt4PGsKnRcY7Sqg559292	intact-crc:B64C59168E79780C|rigid:qeZhAvTXkppjcuZ0FEe42k4EFUM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q03338	uniprotkb:Q96BR9	intact:EBI-421|uniprotkb:D6VT97|ensemblfungi:YDR473C	intact:EBI-742740|uniprotkb:Q8IUL5|uniprotkb:Q8IWR9|uniprotkb:Q8N2Y5|uniprotkb:Q96BX0|ensembl:ENSP00000362609	psi-mi:prp3_yeast(display_long)|uniprotkb:PRP3(gene name)|psi-mi:PRP3(display_short)|uniprotkb:RNA3(gene name synonym)|uniprotkb:YDR473C(locus name)|uniprotkb:D8035.16(orf name)|uniprotkb:Pre-mRNA-splicing factor 3(gene name synonym)	psi-mi:zbt8a_human(display_long)|uniprotkb:ZBTB8A(gene name)|psi-mi:ZBTB8A(display_short)|uniprotkb:BOZF1(gene name synonym)|uniprotkb:BTB/POZ and zinc-finger domain-containing factor(gene name synonym)|uniprotkb:BTB/POZ and zinc-finger domains factor on chromosome 1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11534829|imex:IM-24995-1308	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002881|refseq:NP_010761.3|ensemblfungi:YDR473C(gene)|ensemblfungi:YDR473C_mRNA(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|interpro:IPR010541(Protein of unknown function DUF1115)|interpro:IPR013881(Pre-mRNA-splicing factor 3)|interpro:IPR027104|rcsb pdb:3JCM|rcsb pdb:4YHU|rcsb pdb:4YHV|rcsb pdb:4YHW|rcsb pdb:5GAN|rcsb pdb:5GAP|rcsb pdb:5NRL|rcsb pdb:5ZWM|rcsb pdb:5ZWO|dip:DIP-5266N|mint:Q03338|sgd:YDR473C(identity)	ensembl:ENSG00000160062(gene)|ensembl:ENST00000373510(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|refseq:NP_001035531.2|refseq:NP_001278425.1|entrezgene/locuslink:653121(identity)	-	crc64:E977FD9F708BDD91	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:KE0Y/kRXTq9LXt4PGsKnRcY7Sqg559292	rogid:tsrPT2tHvuBryODKgRXnceXz9s09606	intact-crc:BDE1CF085F39F059|rigid:IVEbIOp9yqdYWIMXWUGgK0gWKck	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q03338	uniprotkb:Q8NHQ1	intact:EBI-421|uniprotkb:D6VT97|ensemblfungi:YDR473C	intact:EBI-739624|ensembl:ENSP00000264982|ensembl:ENSP00000419231|uniprotkb:Q96B31|uniprotkb:Q9H2C3|uniprotkb:Q9H2Z1|uniprotkb:Q9H940|uniprotkb:D3DNE9|uniprotkb:B7Z5I8|uniprotkb:B7Z7E8|uniprotkb:F5GZX8	psi-mi:prp3_yeast(display_long)|uniprotkb:PRP3(gene name)|psi-mi:PRP3(display_short)|uniprotkb:RNA3(gene name synonym)|uniprotkb:YDR473C(locus name)|uniprotkb:D8035.16(orf name)|uniprotkb:Pre-mRNA-splicing factor 3(gene name synonym)	psi-mi:cep70_human(display_long)|uniprotkb:CEP70(gene name)|psi-mi:CEP70(display_short)|uniprotkb:BITE(gene name synonym)|uniprotkb:p10-binding protein(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11534820|imex:IM-24995-1307	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002881|refseq:NP_010761.3|ensemblfungi:YDR473C(gene)|ensemblfungi:YDR473C_mRNA(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|interpro:IPR010541(Protein of unknown function DUF1115)|interpro:IPR013881(Pre-mRNA-splicing factor 3)|interpro:IPR027104|rcsb pdb:3JCM|rcsb pdb:4YHU|rcsb pdb:4YHV|rcsb pdb:4YHW|rcsb pdb:5GAN|rcsb pdb:5GAP|rcsb pdb:5NRL|rcsb pdb:5ZWM|rcsb pdb:5ZWO|dip:DIP-5266N|mint:Q03338|sgd:YDR473C(identity)	ensembl:ENSG00000114107(gene)|ensembl:ENST00000264982(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|interpro:IPR019734|interpro:IPR037692|mint:Q8NHQ1|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|ensembl:ENST00000484888(transcript)|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_077817.2|refseq:XP_016862764.1|refseq:NP_001275893.1|refseq:NP_001275894.1|refseq:NP_001275895.1|refseq:NP_001275896.1|refseq:NP_001307527.1|refseq:NP_001307529.1|entrezgene/locuslink:80321(identity)	-	crc64:E977FD9F708BDD91	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:KE0Y/kRXTq9LXt4PGsKnRcY7Sqg559292	rogid:S4yveQWcvdVtAUX65gqrJ5Dv0Mc9606	intact-crc:A66185D6CE2C2191|rigid:EVMV9nZXPApYzcEVft+zDK3DXyo	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q03338	uniprotkb:Q13422-7	intact:EBI-421|uniprotkb:D6VT97|ensemblfungi:YDR473C	intact:EBI-11522367|ensembl:ENSP00000352123|ensembl:ENSP00000413025	psi-mi:prp3_yeast(display_long)|uniprotkb:PRP3(gene name)|psi-mi:PRP3(display_short)|uniprotkb:RNA3(gene name synonym)|uniprotkb:YDR473C(locus name)|uniprotkb:D8035.16(orf name)|uniprotkb:Pre-mRNA-splicing factor 3(gene name synonym)	psi-mi:q13422-7(display_long)|uniprotkb:IKZF1(gene name)|psi-mi:IKZF1(display_short)|uniprotkb:IK1(gene name synonym)|uniprotkb:IKAROS(gene name synonym)|uniprotkb:Ikaros family zinc finger protein 1(gene name synonym)|uniprotkb:LYF1(gene name synonym)|uniprotkb:Lymphoid transcription factor LyF-1(gene name synonym)|uniprotkb:ZNFN1A1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11534811|imex:IM-24995-1306	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002881|refseq:NP_010761.3|ensemblfungi:YDR473C(gene)|ensemblfungi:YDR473C_mRNA(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|interpro:IPR010541(Protein of unknown function DUF1115)|interpro:IPR013881(Pre-mRNA-splicing factor 3)|interpro:IPR027104|rcsb pdb:3JCM|rcsb pdb:4YHU|rcsb pdb:4YHV|rcsb pdb:4YHW|rcsb pdb:5GAN|rcsb pdb:5GAP|rcsb pdb:5NRL|rcsb pdb:5ZWM|rcsb pdb:5ZWO|dip:DIP-5266N|mint:Q03338|sgd:YDR473C(identity)	intact:EBI-745305(isoform-parent)|ensembl:ENSG00000185811(gene)|ensembl:ENST00000359197(transcript)|ensembl:ENST00000439701(transcript)|uniprotkb:Q13422-7(isoform-parent)|entrezgene/locuslink:10320(identity)	-	crc64:E977FD9F708BDD91	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:KE0Y/kRXTq9LXt4PGsKnRcY7Sqg559292	rogid:ou/ovXYoMneBNVp4pj38VxenfyY9606	intact-crc:F8A3F76757CEBE95|rigid:sTPJqRmLHOwyDW1RvdBNcHNgQ4U	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O14641	uniprotkb:Q03338	intact:EBI-740850|ensembl:ENSP00000005340|uniprotkb:Q53XM0|uniprotkb:D3DTN3	intact:EBI-421|uniprotkb:D6VT97|ensemblfungi:YDR473C	psi-mi:dvl2_human(display_long)|uniprotkb:DSH homolog 2(gene name synonym)|uniprotkb:DVL2(gene name)|psi-mi:DVL2(display_short)	psi-mi:prp3_yeast(display_long)|uniprotkb:PRP3(gene name)|psi-mi:PRP3(display_short)|uniprotkb:RNA3(gene name synonym)|uniprotkb:YDR473C(locus name)|uniprotkb:D8035.16(orf name)|uniprotkb:Pre-mRNA-splicing factor 3(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11534802|imex:IM-24995-1305	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004413.1|ensembl:ENSG00000004975(gene)|ensembl:ENST00000005340(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005109"(frizzled binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0007507"(heart development)|go:"GO:0016235"(aggresome)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044340"(canonical Wnt signaling pathway involved in regulation of cell proliferation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0150012"(positive regulation of neuron projection arborization)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008341(Dishevelled-2 region)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:O14641|rcsb pdb:2REY|rcsb pdb:3CBX|rcsb pdb:3CBY|rcsb pdb:3CBZ|rcsb pdb:3CC0|rcsb pdb:4WIP|rcsb pdb:5LNP|rcsb pdb:5SUY|rcsb pdb:5SUZ|rcsb pdb:6IW3|rcsb pdb:6JCK|reactome:R-HSA-201681|reactome:R-HSA-201688|reactome:R-HSA-2028269|reactome:R-HSA-4086400|reactome:R-HSA-4608870|reactome:R-HSA-4641258|reactome:R-HSA-4641262|reactome:R-HSA-5099900|reactome:R-HSA-5368598|reactome:R-HSA-5663220|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9673324|ensembl:ENSP00000005340|dip:DIP-34433N|entrezgene/locuslink:1856(identity)	sgd:S000002881|refseq:NP_010761.3|ensemblfungi:YDR473C(gene)|ensemblfungi:YDR473C_mRNA(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|interpro:IPR010541(Protein of unknown function DUF1115)|interpro:IPR013881(Pre-mRNA-splicing factor 3)|interpro:IPR027104|rcsb pdb:3JCM|rcsb pdb:4YHU|rcsb pdb:4YHV|rcsb pdb:4YHW|rcsb pdb:5GAN|rcsb pdb:5GAP|rcsb pdb:5NRL|rcsb pdb:5ZWM|rcsb pdb:5ZWO|dip:DIP-5266N|mint:Q03338|sgd:YDR473C(identity)	-	-	crc64:E977FD9F708BDD91	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:2Vdc8oRnT4Mz/j+EXQXrL3AszOc9606	rogid:KE0Y/kRXTq9LXt4PGsKnRcY7Sqg559292	intact-crc:334FB780D8BE854B|rigid:3nza4C1jHUkLd7cvGrIQJ1bmWA4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q03373	uniprotkb:Q9BQY4	intact:EBI-34019|uniprotkb:D6VTA3|ensemblfungi:YDR480W	intact:EBI-372094|uniprotkb:Q9BR00|ensembl:ENSP00000360441	psi-mi:dig2_yeast(display_long)|uniprotkb:DIG2(gene name)|psi-mi:DIG2(display_short)|uniprotkb:Regulator of sterile twelve 2(gene name synonym)|uniprotkb:Regulator of STE12 protein 2(gene name synonym)|uniprotkb:RST2(gene name synonym)|uniprotkb:D8035.23(orf name)|uniprotkb:YDR480W(locus name)	psi-mi:rhxf2_human(display_long)|uniprotkb:RHOXF2(gene name)|psi-mi:RHOXF2(display_short)|uniprotkb:THG1(gene name synonym)|uniprotkb:Paired-like homeobox protein PEPP-2(gene name synonym)|uniprotkb:Testis homeobox gene 1(gene name synonym)|uniprotkb:PEPP2(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11534884|imex:IM-24995-1314	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002888|refseq:NP_010768.1|mint:Q03373|dip:DIP-1292N|ensemblfungi:YDR480W(gene)|ensemblfungi:YDR480W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0008134"(transcription factor binding)|go:"GO:0046020"(negative regulation of transcription from RNA polymerase II promoter by pheromones)|go:"GO:1990526"(Ste12p-Dig1p-Dig2p complex)|go:"GO:2000218"(negative regulation of invasive growth in response to glucose limitation)|go:"GO:2000221"(negative regulation of pseudohyphal growth)|sgd:YDR480W(identity)	refseq:NP_115887.1|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0042802"(identical protein binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|ensembl:ENSG00000131721(gene)|ensembl:ENST00000371388(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|entrezgene/locuslink:84528(identity)	-	crc64:8E71278ED6D3A912	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Uh6OsQDXtmnLKMAEZHl/NTKCEYY559292	rogid:shpgPqf80gNt+gFDv1K+827ELUQ9606	intact-crc:1B370BB5448A7639|rigid:fsCVKuQevcaXnW0lHqXZOKF+bPI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q03373	uniprotkb:P63279	intact:EBI-34019|uniprotkb:D6VTA3|ensemblfungi:YDR480W	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	psi-mi:dig2_yeast(display_long)|uniprotkb:DIG2(gene name)|psi-mi:DIG2(display_short)|uniprotkb:Regulator of sterile twelve 2(gene name synonym)|uniprotkb:Regulator of STE12 protein 2(gene name synonym)|uniprotkb:RST2(gene name synonym)|uniprotkb:D8035.23(orf name)|uniprotkb:YDR480W(locus name)	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11534875|imex:IM-24995-1313	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002888|refseq:NP_010768.1|mint:Q03373|dip:DIP-1292N|ensemblfungi:YDR480W(gene)|ensemblfungi:YDR480W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0008134"(transcription factor binding)|go:"GO:0046020"(negative regulation of transcription from RNA polymerase II promoter by pheromones)|go:"GO:1990526"(Ste12p-Dig1p-Dig2p complex)|go:"GO:2000218"(negative regulation of invasive growth in response to glucose limitation)|go:"GO:2000221"(negative regulation of pseudohyphal growth)|sgd:YDR480W(identity)	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N|entrezgene/locuslink:7329(identity)	-	crc64:8E71278ED6D3A912	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Uh6OsQDXtmnLKMAEZHl/NTKCEYY559292	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	intact-crc:8204DD895CF32A7C|rigid:ijMMvi5+BnGuI045ugOrZ5wp46A	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q03373	uniprotkb:P31947	intact:EBI-34019|uniprotkb:D6VTA3|ensemblfungi:YDR480W	intact:EBI-476295|uniprotkb:Q6FH30|uniprotkb:Q6FH51|uniprotkb:Q96DH0|ensembl:ENSP00000340989|intact:EBI-28970316	psi-mi:dig2_yeast(display_long)|uniprotkb:DIG2(gene name)|psi-mi:DIG2(display_short)|uniprotkb:Regulator of sterile twelve 2(gene name synonym)|uniprotkb:Regulator of STE12 protein 2(gene name synonym)|uniprotkb:RST2(gene name synonym)|uniprotkb:D8035.23(orf name)|uniprotkb:YDR480W(locus name)	psi-mi:1433s_human(display_long)|uniprotkb:Stratifin(gene name synonym)|uniprotkb:Epithelial cell marker protein 1(gene name synonym)|uniprotkb:HME1(gene name synonym)|uniprotkb:SFN(gene name)|psi-mi:SFN(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11534866|imex:IM-24995-1312	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002888|refseq:NP_010768.1|mint:Q03373|dip:DIP-1292N|ensemblfungi:YDR480W(gene)|ensemblfungi:YDR480W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0008134"(transcription factor binding)|go:"GO:0046020"(negative regulation of transcription from RNA polymerase II promoter by pheromones)|go:"GO:1990526"(Ste12p-Dig1p-Dig2p complex)|go:"GO:2000218"(negative regulation of invasive growth in response to glucose limitation)|go:"GO:2000221"(negative regulation of pseudohyphal growth)|sgd:YDR480W(identity)	ensembl:ENSP00000340989|go:"GO:0010839"(negative regulation of keratinocyte proliferation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0031424"(keratinization)|ensembl:ENSG00000175793(gene)|go:"GO:0042802"(identical protein binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|ensembl:ENST00000339276(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0045606"(positive regulation of epidermal cell differentiation)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000308(14-3-3 protein)|go:"GO:0003334"(keratinocyte development)|interpro:IPR023409|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007165"(signal transduction)|go:"GO:0008426"(protein kinase C inhibitor activity)|interpro:IPR023410|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0010482"(regulation of epidermal cell division)|interpro:IPR036815|interpro:IPR037435|mint:P31947|rcsb pdb:1YWT|rcsb pdb:3IQJ|rcsb pdb:3IQU|rcsb pdb:3IQV|rcsb pdb:3LW1|rcsb pdb:3MHR|rcsb pdb:3O8I|rcsb pdb:3P1N|rcsb pdb:3P1O|rcsb pdb:3P1P|rcsb pdb:3P1Q|rcsb pdb:3P1R|rcsb pdb:3P1S|rcsb pdb:3SMK|rcsb pdb:3SML|rcsb pdb:3SMM|rcsb pdb:3SMN|rcsb pdb:3SMO|rcsb pdb:3SP5|rcsb pdb:3SPR|rcsb pdb:3T0L|rcsb pdb:3T0M|rcsb pdb:3U9X|rcsb pdb:3UX0|rcsb pdb:4DAT|rcsb pdb:4DAU|rcsb pdb:4DHM|rcsb pdb:4DHN|rcsb pdb:4DHO|rcsb pdb:4DHP|rcsb pdb:4DHQ|rcsb pdb:4DHR|rcsb pdb:4DHS|rcsb pdb:4DHT|rcsb pdb:4DHU|rcsb pdb:4FL5|rcsb pdb:4FR3|rcsb pdb:4IEA|rcsb pdb:4JC3|rcsb pdb:4JDD|rcsb pdb:4QLI|rcsb pdb:4Y32|rcsb pdb:4Y3B|rcsb pdb:4Y5I|rcsb pdb:5BTV|rcsb pdb:5HF3|rcsb pdb:1YZ5|rcsb pdb:5LTW|rcsb pdb:5LU1|rcsb pdb:5LU2|rcsb pdb:5MHC|rcsb pdb:5MOC|rcsb pdb:5MXO|rcsb pdb:7O34|rcsb pdb:7O3A|rcsb pdb:7O3F|rcsb pdb:7O3P|rcsb pdb:7O3Q|rcsb pdb:7NZV|rcsb pdb:7O3R|rcsb pdb:7O3S|rcsb pdb:7O57|rcsb pdb:7O59|rcsb pdb:7O5A|rcsb pdb:7O5C|rcsb pdb:7O5D|rcsb pdb:7O5F|rcsb pdb:7O5G|rcsb pdb:7O5O|rcsb pdb:7O5P|rcsb pdb:7O5S|rcsb pdb:7O5U|rcsb pdb:7O5X|rcsb pdb:7O6F|rcsb pdb:7O6G|rcsb pdb:7O6I|rcsb pdb:7O6J|rcsb pdb:7O6K|rcsb pdb:7O6M|rcsb pdb:7O6O|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-5625740|reactome:R-HSA-5628897|rcsb pdb:6GHP|rcsb pdb:6HHP|rcsb pdb:6HKB|rcsb pdb:6HKF|rcsb pdb:6HMT|rcsb pdb:6G8Q|rcsb pdb:6HMU|rcsb pdb:6HN2|rcsb pdb:6NV2|rcsb pdb:6QDR|rcsb pdb:6QDS|rcsb pdb:6QDT|rcsb pdb:6QDU|rcsb pdb:6QHL|rcsb pdb:6QHM|rcsb pdb:6QIU|rcsb pdb:6QZR|rcsb pdb:6QZS|rcsb pdb:6R5L|rcsb pdb:6RHC|rcsb pdb:6RJL|rcsb pdb:6RJQ|rcsb pdb:6RJZ|rcsb pdb:6RK8|rcsb pdb:6RKI|rcsb pdb:6RKK|rcsb pdb:6RKM|rcsb pdb:6RL3|rcsb pdb:6RL4|rcsb pdb:6RL6|rcsb pdb:6RM5|rcsb pdb:6RM7|rcsb pdb:6RP6|rcsb pdb:6RWH|rcsb pdb:6RWI|rcsb pdb:5MYC|rcsb pdb:5N5R|rcsb pdb:5N5T|rcsb pdb:5N5W|rcsb pdb:5N75|rcsb pdb:5OEG|rcsb pdb:5OEH|rcsb pdb:5OK9|rcsb pdb:5OKF|rcsb pdb:5OM0|rcsb pdb:5OMA|rcsb pdb:6FAU|rcsb pdb:6FAV|rcsb pdb:6FAW|rcsb pdb:6FBB|rcsb pdb:6FBW|rcsb pdb:6FBY|rcsb pdb:6FCP|rcsb pdb:6FI4|rcsb pdb:6FI5|rcsb pdb:6G6X|rcsb pdb:6G8I|rcsb pdb:5MY9|rcsb pdb:6G8J|rcsb pdb:6G8K|rcsb pdb:6G8L|rcsb pdb:6G8P|rcsb pdb:6RWS|rcsb pdb:6TJM|rcsb pdb:6TL3|rcsb pdb:6RWU|rcsb pdb:6TLF|rcsb pdb:6TLG|rcsb pdb:6TM7|rcsb pdb:6TWZ|rcsb pdb:6W0L|rcsb pdb:6XWD|rcsb pdb:6XXC|rcsb pdb:6XY5|rcsb pdb:6Y18|rcsb pdb:6Y1D|rcsb pdb:6Y1J|rcsb pdb:6RX2|rcsb pdb:6S39|rcsb pdb:6S3C|rcsb pdb:6S40|rcsb pdb:6Y3M|rcsb pdb:6Y3O|rcsb pdb:6Y3R|rcsb pdb:6Y3S|rcsb pdb:6Y3V|rcsb pdb:6Y3W|rcsb pdb:6Y40|rcsb pdb:6S9Q|rcsb pdb:6Y44|rcsb pdb:6SIN|rcsb pdb:6Y58|rcsb pdb:6SIO|rcsb pdb:6Y7T|rcsb pdb:6SIP|rcsb pdb:6Y8A|rcsb pdb:6Y8B|rcsb pdb:6Y8D|rcsb pdb:6SIQ|rcsb pdb:6Y8E|rcsb pdb:6YE9|rcsb pdb:6YIA|rcsb pdb:6SLV|rcsb pdb:6YIB|rcsb pdb:6YIC|rcsb pdb:6YLU|rcsb pdb:6YOW|rcsb pdb:6YOX|rcsb pdb:6YOY|rcsb pdb:6YP2|rcsb pdb:6YP3|rcsb pdb:6YP8|rcsb pdb:6SLW|rcsb pdb:6SLX|rcsb pdb:6T5F|rcsb pdb:6T5H|rcsb pdb:6T80|rcsb pdb:6TCH|rcsb pdb:6YPL|rcsb pdb:6YPY|rcsb pdb:6YQ2|rcsb pdb:6ZCJ|rcsb pdb:7AEW|rcsb pdb:7AOG|rcsb pdb:7AXN|rcsb pdb:7AYF|rcsb pdb:7AZ1|rcsb pdb:7AZ2|rcsb pdb:7BDP|rcsb pdb:7BDT|rcsb pdb:7BDY|rcsb pdb:7BFW|rcsb pdb:7BG3|rcsb pdb:7BGQ|rcsb pdb:7BGR|rcsb pdb:7BGV|rcsb pdb:7BGW|rcsb pdb:7BI3|rcsb pdb:7BIQ|rcsb pdb:7BIY|rcsb pdb:7BJF|rcsb pdb:7BJL|rcsb pdb:7BJW|rcsb pdb:7BKH|rcsb pdb:7NFW|rcsb pdb:7NIF|rcsb pdb:7NIG|rcsb pdb:7NIX|rcsb pdb:7NJ6|rcsb pdb:7NJ8|rcsb pdb:7NJ9|rcsb pdb:7NJA|rcsb pdb:7NJB|rcsb pdb:7NK3|rcsb pdb:7NK5|rcsb pdb:7NLA|rcsb pdb:7NLE|rcsb pdb:7NM1|rcsb pdb:7NM3|rcsb pdb:7NM9|rcsb pdb:7NQP|rcsb pdb:7NR7|rcsb pdb:7NRK|rcsb pdb:7NRL|rcsb pdb:7NSV|rcsb pdb:7NV4|rcsb pdb:7NVI|rcsb pdb:7NWS|rcsb pdb:7NXS|rcsb pdb:7NXT|rcsb pdb:7NXW|rcsb pdb:7NXY|rcsb pdb:7NY4|rcsb pdb:7NYE|rcsb pdb:7NYF|rcsb pdb:7NYG|rcsb pdb:7NZ6|rcsb pdb:7NZG|rcsb pdb:7NZK|reactome:R-HSA-6804114|reactome:R-HSA-75035|reactome:R-HSA-9614399|refseq:NP_006133.1|dip:DIP-29861N|entrezgene/locuslink:2810(identity)	-	crc64:8E71278ED6D3A912	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Uh6OsQDXtmnLKMAEZHl/NTKCEYY559292	rogid:HI+I1sXZRxVaRy9nzl3O0HmaSSE9606	intact-crc:C4BC6E74440DBBC6|rigid:tQVJ4k2Zv3BGIQUdO+iwOfZEkx8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q03362	uniprotkb:Q9BSE4	intact:EBI-2057915|uniprotkb:D6VT99|ensemblfungi:YDR476C	intact:EBI-2868124|uniprotkb:A4D1Y8|uniprotkb:Q9H6F9|ensembl:ENSP00000310729|ensembl:ENSP00000379390	psi-mi:yd476_yeast(display_long)|uniprotkb:YDR476C(locus name)	psi-mi:herp2_human(display_long)|uniprotkb:HERPUD2(gene name)|psi-mi:HERPUD2(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11534857|imex:IM-24995-1311	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002884|refseq:NP_010764.1|mint:Q03362|ensemblfungi:YDR476C(gene)|ensemblfungi:YDR476C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|sgd:YDR476C(identity)	refseq:NP_071768.3|refseq:XP_016867995.1|ensembl:ENSG00000122557(gene)|ensembl:ENST00000311350(transcript)|ensembl:ENST00000396081(transcript)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|interpro:IPR000626(Ubiquitin)|interpro:IPR029071|interpro:IPR039751|rcsb pdb:2KDB|entrezgene/locuslink:64224(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:YEqaI+xtDR2srSbbY5vQtWY+h6s559292	rogid:h4jBbYdKwKQBN6Jd3/QQA0hNOQw9606	intact-crc:688A93BEA5855391|rigid:OJa1EzKTf96bXA5efxhhBZ6EO/s	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96BA8	uniprotkb:Q03362	intact:EBI-6942903|ensembl:ENSP00000481956|intact:MINT-268046|intact:MINT-8162577|uniprotkb:Q8N2D5|uniprotkb:Q96CP0	intact:EBI-2057915|uniprotkb:D6VT99|ensemblfungi:YDR476C	psi-mi:cr3l1_human(display_long)|uniprotkb:CREB3L1(gene name)|psi-mi:CREB3L1(display_short)|uniprotkb:OASIS(gene name synonym)|uniprotkb:PSEC0238(orf name)|uniprotkb:Old astrocyte specifically-induced substance(gene name synonym)	psi-mi:yd476_yeast(display_long)|uniprotkb:YDR476C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11534847|imex:IM-24995-1310	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157613(gene)|ensembl:ENST00000621158(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0070278"(extracellular matrix constituent secretion)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029805|mint:Q96BA8|reactome:R-HSA-8874211|refseq:NP_443086.1|entrezgene/locuslink:90993(identity)	sgd:S000002884|refseq:NP_010764.1|mint:Q03362|ensemblfungi:YDR476C(gene)|ensemblfungi:YDR476C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|sgd:YDR476C(identity)	-	comment:mint|function:"Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE"	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:sMWUFmBeBBCO+T0Y2CuB/un1lBg9606	rogid:YEqaI+xtDR2srSbbY5vQtWY+h6s559292	intact-crc:A9924DE208291489|rigid:7R5TCt7NUJ/xrrYIJFayBGRGKLQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q03654	uniprotkb:Q5JR59-3	intact:EBI-476|uniprotkb:Q6B1D8|ensemblfungi:YMR213W|uniprotkb:D6W038	intact:EBI-11522433|ensembl:ENSP00000370186	psi-mi:cef1_yeast(display_long)|uniprotkb:CEF1(gene name)|psi-mi:CEF1(display_short)|uniprotkb:YMR213W(locus name)|uniprotkb:YM8261.07(orf name)|uniprotkb:NTC85(gene name synonym)|uniprotkb:PRP nineteen-associated complex protein 85(gene name synonym)|uniprotkb:PRP19-associated complex protein 85(gene name synonym)	psi-mi:q5jr59-3(display_long)|uniprotkb:MTUS2(gene name)|psi-mi:MTUS2(display_short)|uniprotkb:CAZIP(gene name synonym)|uniprotkb:Cardiac zipper protein(gene name synonym)|uniprotkb:KIAA0774(gene name synonym)|uniprotkb:Microtubule plus-end tracking protein TIP150(gene name synonym)|uniprotkb:TIP150(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11534913|imex:IM-24995-1317	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013940.1|sgd:S000004826|ensemblfungi:YMR213W(gene)|ensemblfungi:YMR213W_mRNA(transcript)|go:"GO:0000350"(generation of catalytic spliceosome for second transesterification step)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000974"(Prp19 complex)|go:"GO:0003677"(DNA binding)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017930|interpro:IPR021786|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|rcsb pdb:7DCO|dip:DIP-1113N|mint:Q03654|sgd:YMR213W(identity)	ensembl:ENSG00000132938(gene)|ensembl:ENST00000380808(transcript)|intact:EBI-742948(isoform-parent)|uniprotkb:Q5JR59-3(isoform-parent)|entrezgene/locuslink:23281(identity)	-	crc64:A4C417A8B330EA9C	isoform-comment:No experimental confirmation available.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:AsbV7RtNk+8mCzLk2wZYqbULOFg559292	rogid:npId9tC7VoLN/jteoBiRbSYChPs9606	intact-crc:27B13C6D8B89F91A|rigid:bQMRsdSCaKABsIAcLn26s2IoIpM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:G5E962	uniprotkb:Q03654	intact:EBI-11525615|ensembl:ENSP00000328177	intact:EBI-476|uniprotkb:Q6B1D8|ensemblfungi:YMR213W|uniprotkb:D6W038	psi-mi:g5e962_human(display_long)|uniprotkb:hCG_1644200(orf name)|uniprotkb:MAGEA11(gene name)|psi-mi:MAGEA11(display_short)	psi-mi:cef1_yeast(display_long)|uniprotkb:CEF1(gene name)|psi-mi:CEF1(display_short)|uniprotkb:YMR213W(locus name)|uniprotkb:YM8261.07(orf name)|uniprotkb:NTC85(gene name synonym)|uniprotkb:PRP nineteen-associated complex protein 85(gene name synonym)|uniprotkb:PRP19-associated complex protein 85(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11534902|imex:IM-24995-1316	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001011544.1|ensembl:ENSG00000185247(gene)|ensembl:ENST00000333104(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016604"(nuclear body)|interpro:IPR002190(MAGE protein)|interpro:IPR021072|interpro:IPR030099|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|entrezgene/locuslink:4110(identity)	refseq:NP_013940.1|sgd:S000004826|ensemblfungi:YMR213W(gene)|ensemblfungi:YMR213W_mRNA(transcript)|go:"GO:0000350"(generation of catalytic spliceosome for second transesterification step)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000974"(Prp19 complex)|go:"GO:0003677"(DNA binding)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017930|interpro:IPR021786|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|rcsb pdb:7DCO|dip:DIP-1113N|mint:Q03654|sgd:YMR213W(identity)	-	-	crc64:A4C417A8B330EA9C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:sVB0aA6yibWUx/d2SE+pwpKKgtI9606	rogid:AsbV7RtNk+8mCzLk2wZYqbULOFg559292	intact-crc:90099101EBFD6675|rigid:L+RpFPw6IWhOHFNjUFked8U1UUM	false	sufficient binding region:82-400	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q03579	uniprotkb:Q8N6L0	intact:EBI-27640|uniprotkb:D6W0C5|ensemblfungi:YMR298W	intact:EBI-749265|uniprotkb:Q96MC3|ensembl:ENSP00000404220	psi-mi:lip1_yeast(display_long)|uniprotkb:YMR298W(locus name)|uniprotkb:LIP1(gene name)|psi-mi:LIP1(display_short)|uniprotkb:LAG1/LAC1-interacting protein 1(gene name synonym)	psi-mi:kash5_human(display_long)|uniprotkb:KASH5(gene name)|psi-mi:KASH5(display_short)|uniprotkb:CCDC155(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 155(gene name synonym)|uniprotkb:KASH domain-containing protein 5(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11534893|imex:IM-24995-1315	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014027.1|sgd:S000004913|dip:DIP-4392N|ensemblfungi:YMR298W(gene)|ensemblfungi:YMR298W_mRNA(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:0061576"(acyl-CoA ceramide synthase complex)|sgd:YMR298W(identity)	refseq:NP_653289.3|ensembl:ENSG00000161609(gene)|ensembl:ENST00000447857(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034397"(telomere localization)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051225"(spindle assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0090172"(microtubule cytoskeleton organization involved in homologous chromosome segregation)|go:"GO:0090220"(chromosome localization to nuclear envelope involved in homologous chromosome segregation)|go:"GO:0090619"(meiotic spindle pole)|interpro:IPR011992(EF-Hand type)|interpro:IPR028168|interpro:IPR028170|interpro:IPR039508|mint:Q8N6L0|rcsb pdb:6R2I|rcsb pdb:6WMF|entrezgene/locuslink:147872(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:9Z3aO01R1mik+xM40fm/dy+A/ec559292	rogid:Wl9L7AcvDHCZuKjYLn8QgGIbZTc9606	intact-crc:0595A357D6A33947|rigid:4vBKopNrNkdVE82v9RXyHdI6Soc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q03718	uniprotkb:Q9Y6D9	intact:EBI-27756|uniprotkb:D6VZF1|ensemblfungi:YML023C	intact:EBI-742610|uniprotkb:B3KR41|uniprotkb:Q9UNH0|uniprotkb:Q13312|uniprotkb:Q75MI0|uniprotkb:Q86UM4|ensembl:ENSP00000265854|ensembl:ENSP00000382562|ensembl:ENSP00000385334	psi-mi:nse5_yeast(display_long)|uniprotkb:YML023C(locus name)|uniprotkb:NSE5(gene name)|psi-mi:NSE5(display_short)	psi-mi:md1l1_human(display_long)|uniprotkb:Mitotic arrest deficient 1-like protein 1(gene name synonym)|uniprotkb:Mitotic checkpoint MAD1 protein homolog(gene name synonym)|uniprotkb:Tax-binding protein 181(gene name synonym)|uniprotkb:MAD1L1(gene name)|psi-mi:MAD1L1(display_short)|uniprotkb:MAD1(gene name synonym)|uniprotkb:TXBP181(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11534959|imex:IM-24995-1322	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013689.1|sgd:S000004485|dip:DIP-4547N|ensemblfungi:YML023C(gene)|ensemblfungi:YML023C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0016925"(protein sumoylation)|go:"GO:0030915"(Smc5-Smc6 complex)|interpro:IPR014803(DNA repair protein Nse5)|rcsb pdb:7LTO|sgd:YML023C(identity)	refseq:NP_001013858.1|refseq:NP_001013859.1|refseq:NP_003541.2|refseq:NP_001291452.1|refseq:NP_001291453.1|ensembl:ENSG00000002822(gene)|ensembl:ENST00000265854(transcript)|go:"GO:0090235"(regulation of metaphase plate congression)|go:"GO:1902426"(deactivation of mitotic spindle assembly checkpoint)|interpro:IPR008672(Mitotic checkpoint)|mint:Q9Y6D9|rcsb pdb:1GO4|rcsb pdb:4DZO|rcsb pdb:7B1F|rcsb pdb:7B1H|rcsb pdb:7B1J|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|ensembl:ENST00000399654(transcript)|ensembl:ENST00000406869(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043515"(kinetochore binding)|go:"GO:0044615"(nuclear pore nuclear basket)|go:"GO:0048538"(thymus development)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0072686"(mitotic spindle)|refseq:XP_005249934.1|dip:DIP-29654N|entrezgene/locuslink:8379(identity)	-	crc64:6680A04D91E537DD	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:xDmbHW4E/uX4NGGcDCMXTnUDQGk559292	rogid:9CcqpZlN0IgqC939rIo7vNgOvLQ9606	intact-crc:AC93DF59093FE6CF|rigid:xPpbcd/v/e7dd9G01hJetUFUDS8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q03718	uniprotkb:P63279	intact:EBI-27756|uniprotkb:D6VZF1|ensemblfungi:YML023C	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	psi-mi:nse5_yeast(display_long)|uniprotkb:YML023C(locus name)|uniprotkb:NSE5(gene name)|psi-mi:NSE5(display_short)	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11534950|imex:IM-24995-1321	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013689.1|sgd:S000004485|dip:DIP-4547N|ensemblfungi:YML023C(gene)|ensemblfungi:YML023C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0016925"(protein sumoylation)|go:"GO:0030915"(Smc5-Smc6 complex)|interpro:IPR014803(DNA repair protein Nse5)|rcsb pdb:7LTO|sgd:YML023C(identity)	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N|entrezgene/locuslink:7329(identity)	-	crc64:6680A04D91E537DD	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:xDmbHW4E/uX4NGGcDCMXTnUDQGk559292	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	intact-crc:CD83A80D94856A62|rigid:uLlN/Eozbz0vf94J6UEzlw91zWI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8N6L0	uniprotkb:Q03714	intact:EBI-749265|uniprotkb:Q96MC3|ensembl:ENSP00000404220	intact:EBI-27760|uniprotkb:D6VZE5|ensemblfungi:YML029W	psi-mi:kash5_human(display_long)|uniprotkb:KASH5(gene name)|psi-mi:KASH5(display_short)|uniprotkb:CCDC155(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 155(gene name synonym)|uniprotkb:KASH domain-containing protein 5(gene name synonym)	psi-mi:usa1_yeast(display_long)|uniprotkb:USA1(gene name)|psi-mi:USA1(display_short)|uniprotkb:YML029W(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11534941|imex:IM-24995-1320	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_653289.3|ensembl:ENSG00000161609(gene)|ensembl:ENST00000447857(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034397"(telomere localization)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051225"(spindle assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0090172"(microtubule cytoskeleton organization involved in homologous chromosome segregation)|go:"GO:0090220"(chromosome localization to nuclear envelope involved in homologous chromosome segregation)|go:"GO:0090619"(meiotic spindle pole)|interpro:IPR011992(EF-Hand type)|interpro:IPR028168|interpro:IPR028170|interpro:IPR039508|mint:Q8N6L0|rcsb pdb:6R2I|rcsb pdb:6WMF|entrezgene/locuslink:147872(identity)	refseq:NP_013683.1|sgd:S000004491|dip:DIP-6423N|mint:Q03714|ensemblfungi:YML029W(gene)|ensemblfungi:YML029W_mRNA(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:1902499"(positive regulation of protein autoubiquitination)|interpro:IPR000626(Ubiquitin)|interpro:IPR029071|rcsb pdb:6VJZ|rcsb pdb:6VK0|sgd:YML029W(identity)	-	-	crc64:9B93ECA6C5421FD6	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Wl9L7AcvDHCZuKjYLn8QgGIbZTc9606	rogid:k5/W6R8NnkOWchVSQSoXCbvaAZ8559292	intact-crc:4FDD6A744A21EA34|rigid:CfZ0q15whvyngzr6nXKsflD12lg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96BA8	uniprotkb:Q03697	intact:EBI-6942903|ensembl:ENSP00000481956|intact:MINT-268046|intact:MINT-8162577|uniprotkb:Q8N2D5|uniprotkb:Q96CP0	intact:EBI-27776|uniprotkb:D6VZD7|ensemblfungi:YML038C	psi-mi:cr3l1_human(display_long)|uniprotkb:CREB3L1(gene name)|psi-mi:CREB3L1(display_short)|uniprotkb:OASIS(gene name synonym)|uniprotkb:PSEC0238(orf name)|uniprotkb:Old astrocyte specifically-induced substance(gene name synonym)	psi-mi:ymd8_yeast(display_long)|uniprotkb:YML038C(locus name)|uniprotkb:YMD8(gene name)|psi-mi:YMD8(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11534931|imex:IM-24995-1319	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157613(gene)|ensembl:ENST00000621158(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0070278"(extracellular matrix constituent secretion)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029805|mint:Q96BA8|reactome:R-HSA-8874211|refseq:NP_443086.1|entrezgene/locuslink:90993(identity)	refseq:NP_013674.1|sgd:S000004502|dip:DIP-1312N|mint:Q03697|ensemblfungi:YML038C(gene)|ensemblfungi:YML038C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005338"(nucleotide-sugar transmembrane transporter activity)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0008643"(carbohydrate transport)|go:"GO:0015297"(antiporter activity)|go:"GO:0015780"(nucleotide-sugar transmembrane transport)|go:"GO:0015786"(UDP-glucose transmembrane transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030663"(COPI-coated vesicle membrane)|interpro:IPR004853(Protein of unknown function DUF250)|sgd:YML038C(identity)	-	comment:mint|function:"Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE"	crc64:37A03543D3AB695E	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:sMWUFmBeBBCO+T0Y2CuB/un1lBg9606	rogid:i2Fqb84s31vBiayw4lJW8o3S3WU559292	intact-crc:D9A23041D94ECFDF|rigid:QWAjWChgf4EUv0/21VdKrY0yHr4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q03654	uniprotkb:Q96MT8-3	intact:EBI-476|uniprotkb:Q6B1D8|ensemblfungi:YMR213W|uniprotkb:D6W038	intact:EBI-11522539|ensembl:ENSP00000507703|ensembl:ENSP00000328382|ensembl:ENSP00000506728|ensembl:ENSP00000506791|ensembl:ENSP00000506828|ensembl:ENSP00000507228	psi-mi:cef1_yeast(display_long)|uniprotkb:CEF1(gene name)|psi-mi:CEF1(display_short)|uniprotkb:YMR213W(locus name)|uniprotkb:YM8261.07(orf name)|uniprotkb:NTC85(gene name synonym)|uniprotkb:PRP nineteen-associated complex protein 85(gene name synonym)|uniprotkb:PRP19-associated complex protein 85(gene name synonym)	psi-mi:q96mt8-3(display_long)|uniprotkb:CEP63(gene name)|psi-mi:CEP63(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11534922|imex:IM-24995-1318	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013940.1|sgd:S000004826|ensemblfungi:YMR213W(gene)|ensemblfungi:YMR213W_mRNA(transcript)|go:"GO:0000350"(generation of catalytic spliceosome for second transesterification step)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000974"(Prp19 complex)|go:"GO:0003677"(DNA binding)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017930|interpro:IPR021786|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|rcsb pdb:7DCO|dip:DIP-1113N|mint:Q03654|sgd:YMR213W(identity)	intact:EBI-741977(isoform-parent)|ensembl:ENST00000332047(transcript)|ensembl:ENST00000682042(transcript)|ensembl:ENST00000682800(transcript)|ensembl:ENST00000682858(transcript)|ensembl:ENST00000683177(transcript)|ensembl:ENST00000683861(transcript)|ensembl:ENSG00000182923(gene)|uniprotkb:Q96MT8-3(isoform-parent)|entrezgene/locuslink:80254(identity)	-	crc64:A4C417A8B330EA9C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:AsbV7RtNk+8mCzLk2wZYqbULOFg559292	rogid:U0uvVcOCzA8Qp2cCB0ilixgd4Yc9606	intact-crc:737B3801F2C49713|rigid:M1Vh7K1UdJklmCjhPNABta8/GdY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q03782	uniprotkb:Q9NYB9-2	intact:EBI-627|uniprotkb:D6VSM1|ensemblfungi:YDR240C	intact:EBI-11096309|ensembl:ENSP00000261017	psi-mi:snu56_yeast(display_long)|uniprotkb:YDR240C(locus name)|uniprotkb:SNU56(gene name)|psi-mi:SNU56(display_short)|uniprotkb:MUD10(gene name synonym)	psi-mi:q9nyb9-2(display_long)|uniprotkb:ABI2(gene name)|psi-mi:ABI2(display_short)|uniprotkb:ARGBPIA(gene name synonym)|uniprotkb:Abelson interactor 2(gene name synonym)|uniprotkb:Abl-binding protein 3(gene name synonym)|uniprotkb:Arg-binding protein 1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11534995|imex:IM-24995-1326	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002648|refseq:NP_010526.1|dip:DIP-6514N|mint:Q03782|ensemblfungi:YDR240C(gene)|ensemblfungi:YDR240C_mRNA(transcript)|go:"GO:0000243"(commitment complex)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005685"(U1 snRNP)|go:"GO:0071004"(U2-type prespliceosome)|interpro:IPR043954|rcsb pdb:5ZWN|rcsb pdb:6G90|rcsb pdb:6N7P|rcsb pdb:6N7R|rcsb pdb:6N7X|sgd:YDR240C(identity)	intact:EBI-743598(isoform-parent)|ensembl:ENSG00000138443(gene)|ensembl:ENST00000261017(transcript)|uniprotkb:Q9NYB9-2(isoform-parent)|entrezgene/locuslink:10152(identity)	-	crc64:5E0C7A1FD577808F	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:gz3aUh/8pFF7Yn8XS9gdhSWrVNs559292	rogid:VNi9aUeavD8+CCi+n1DXS+7mmbs9606	intact-crc:3D5194A6715949CD|rigid:9EPgDys2FUgB+pXASx5eV7k66h4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P43355	uniprotkb:Q03782	intact:EBI-740978|ensembl:ENSP00000349085|uniprotkb:O00346|uniprotkb:B2RC81	intact:EBI-627|uniprotkb:D6VSM1|ensemblfungi:YDR240C	psi-mi:maga1_human(display_long)|uniprotkb:MAGE-1 antigen(gene name synonym)|uniprotkb:Antigen MZ2-E(gene name synonym)|uniprotkb:Cancer/testis antigen 1.1(gene name synonym)|uniprotkb:MAGEA1(gene name)|psi-mi:MAGEA1(display_short)|uniprotkb:MAGE1(gene name synonym)|uniprotkb:MAGE1A(gene name synonym)	psi-mi:snu56_yeast(display_long)|uniprotkb:YDR240C(locus name)|uniprotkb:SNU56(gene name)|psi-mi:SNU56(display_short)|uniprotkb:MUD10(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11534986|imex:IM-24995-1325	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004979.3|ensembl:ENSG00000198681(gene)|ensembl:ENST00000356661(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|interpro:IPR002190(MAGE protein)|interpro:IPR021072|interpro:IPR030093|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|rcsb pdb:1W72|rcsb pdb:3BO8|dip:DIP-54794N|entrezgene/locuslink:4100(identity)	sgd:S000002648|refseq:NP_010526.1|dip:DIP-6514N|mint:Q03782|ensemblfungi:YDR240C(gene)|ensemblfungi:YDR240C_mRNA(transcript)|go:"GO:0000243"(commitment complex)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005685"(U1 snRNP)|go:"GO:0071004"(U2-type prespliceosome)|interpro:IPR043954|rcsb pdb:5ZWN|rcsb pdb:6G90|rcsb pdb:6N7P|rcsb pdb:6N7R|rcsb pdb:6N7X|sgd:YDR240C(identity)	-	crc64:544EEB1F9F4E9D33	crc64:5E0C7A1FD577808F	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:6XW3mnTNM3yvOtXmiFbU8Uz3hjA9606	rogid:gz3aUh/8pFF7Yn8XS9gdhSWrVNs559292	intact-crc:EF79C948EC9E70A4|rigid:mWzhpwpq6fEPBATJay05BGCidGM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96AA8	uniprotkb:Q03768	intact:EBI-752007|uniprotkb:O60302|uniprotkb:B4DSG0|uniprotkb:A4ZZA7|uniprotkb:Q548S1|uniprotkb:A8K5G5|uniprotkb:G5E9Y0|ensembl:ENSP00000265272	intact:EBI-7618|uniprotkb:D6VSD4|ensemblfungi:YDR152W	psi-mi:jkip2_human(display_long)|uniprotkb:JAMIP2(gene name synonym)|uniprotkb:NECC1(gene name synonym)|uniprotkb:Neuroendocrine long coiled-coil protein 1(gene name synonym)|uniprotkb:CTCL tumor antigen HD-CL-04(gene name synonym)|uniprotkb:JAKMIP2(gene name)|psi-mi:JAKMIP2(display_short)|uniprotkb:KIAA0555(gene name synonym)	psi-mi:gir2_yeast(display_long)|uniprotkb:GIR2(gene name)|psi-mi:GIR2(display_short)|uniprotkb:YDR152W(locus name)|uniprotkb:YD8358.08(orf name)|uniprotkb:DFRP2(gene name synonym)|uniprotkb:DRG family-regulatory protein 2(gene name synonym)|uniprotkb:Genetically interacts with ribosomal genes protein 2(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11534977|imex:IM-24995-1324	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055605.2|refseq:NP_001257870.1|refseq:NP_001257863.1|refseq:NP_001269211.1|refseq:XP_016865586.1|ensembl:ENSG00000176049(gene)|ensembl:ENST00000265272(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0008017"(microtubule binding)|go:"GO:0019900"(kinase binding)|interpro:IPR024836|interpro:IPR031994|entrezgene/locuslink:9832(identity)	sgd:S000002559|refseq:NP_010436.3|mint:Q03768|dip:DIP-1751N|ensemblfungi:YDR152W(gene)|ensemblfungi:YDR152W_mRNA(transcript)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005844"(polysome)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:1903833"(positive regulation of cellular response to amino acid starvation)|interpro:IPR006575(RWD)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR040213|sgd:YDR152W(identity)	-	-	crc64:CE09A067388638ED	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:WnaHkeDBQXut9F9AzzaCrDYpmAE9606	rogid:2gb8Bf2IGl8RoOmNcIvEMlmgeTE559292	intact-crc:65684769F2053F51|rigid:f3XZjsvsBmJONZLjVfhud9qGzeo	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q03759	uniprotkb:Q5JST6	intact:EBI-27937|uniprotkb:D6W0H6|ensemblfungi:YML108W	intact:EBI-2349927|uniprotkb:Q9H653|uniprotkb:Q5JST8|uniprotkb:Q68DK4|uniprotkb:Q8NEI0|intact:EBI-28971886|ensembl:ENSP00000404232	psi-mi:ymk8_yeast(display_long)|uniprotkb:YM8339.11(orf name)|uniprotkb:YML108W(locus name)	psi-mi:efhc2_human(display_long)|uniprotkb:EFHC2(gene name)|psi-mi:EFHC2(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11534968|imex:IM-24995-1323	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013599.1|sgd:S000004576|dip:DIP-3849N|ensemblfungi:YML108W(gene)|ensemblfungi:YML108W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|interpro:IPR015080(Protein of unknown function DUF1892)|interpro:IPR035946|rcsb pdb:1N6Z|sgd:YML108W(identity)	ensembl:ENSP00000404232|refseq:NP_079460.2|ensembl:ENSG00000183690(gene)|ensembl:ENST00000420999(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005930"(axoneme)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0060285"(cilium-dependent cell motility)|go:"GO:0072686"(mitotic spindle)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR006602(Region of unknown function DM10)|interpro:IPR011992(EF-Hand type)|interpro:IPR040193|rcsb pdb:2Z13|rcsb pdb:2Z14|entrezgene/locuslink:80258(identity)	-	crc64:8D07986085C369C4	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:SLeZv2kwwNuEtzk4nFkrHoP4HOo559292	rogid:O1XriQSkLcYkk7H7AlanQ1FKIBY9606	intact-crc:68E5A88BB03E4D87|rigid:5cqc0lY4K7kuTXTQS+ghLIml7NU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q03860	uniprotkb:Q8N6L0	intact:EBI-37537|uniprotkb:D6VS87|ensemblfungi:YDR100W	intact:EBI-749265|uniprotkb:Q96MC3|ensembl:ENSP00000404220	psi-mi:tvp15_yeast(display_long)|uniprotkb:YDR100W(locus name)|uniprotkb:TVP15(gene name)|psi-mi:TVP15(display_short)|uniprotkb:TLG2 compartment vesicle protein 15(gene name synonym)|uniprotkb:TLG2-vesicle protein of 15 kDa(gene name synonym)	psi-mi:kash5_human(display_long)|uniprotkb:KASH5(gene name)|psi-mi:KASH5(display_short)|uniprotkb:CCDC155(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 155(gene name synonym)|uniprotkb:KASH domain-containing protein 5(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11535004|imex:IM-24995-1327	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002507|refseq:NP_010385.3|dip:DIP-2049N|mint:Q03860|ensemblfungi:YDR100W(gene)|ensemblfungi:YDR100W_mRNA(transcript)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0042802"(identical protein binding)|interpro:IPR013714(COPI associated)|sgd:YDR100W(identity)	refseq:NP_653289.3|ensembl:ENSG00000161609(gene)|ensembl:ENST00000447857(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034397"(telomere localization)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051225"(spindle assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0090172"(microtubule cytoskeleton organization involved in homologous chromosome segregation)|go:"GO:0090220"(chromosome localization to nuclear envelope involved in homologous chromosome segregation)|go:"GO:0090619"(meiotic spindle pole)|interpro:IPR011992(EF-Hand type)|interpro:IPR028168|interpro:IPR028170|interpro:IPR039508|mint:Q8N6L0|rcsb pdb:6R2I|rcsb pdb:6WMF|entrezgene/locuslink:147872(identity)	-	crc64:395F700FBB14C569	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:WUrBFK6BrbdV4tMhayDYqINQ5FM559292	rogid:Wl9L7AcvDHCZuKjYLn8QgGIbZTc9606	intact-crc:65CAB9FB2C090888|rigid:fuv98/dOVC/xa5CEB2tu0K6VsSg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9BUY5	uniprotkb:Q03920	intact:EBI-743265|ensembl:ENSP00000253115|ensembl:ENSP00000439017|uniprotkb:B3KTL2	intact:EBI-31378|uniprotkb:D6VSC3|ensemblfungi:YDR140W	psi-mi:zn426_human(display_long)|uniprotkb:ZNF426(gene name)|psi-mi:ZNF426(display_short)	psi-mi:mtq2_yeast(display_long)|uniprotkb:MTQ2(gene name)|psi-mi:MTQ2(display_short)|uniprotkb:MTC6(gene name synonym)|uniprotkb:"N(5)-glutamine methyltransferase MTQ2"(gene name synonym)|uniprotkb:YDR140W(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11535022|imex:IM-24995-1329	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_077011.1|ensembl:ENSG00000130818(gene)|ensembl:ENST00000253115(transcript)|ensembl:ENST00000535489(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|refseq:NP_001304984.1|refseq:NP_001304985.1|entrezgene/locuslink:79088(identity)	refseq:NP_010424.3|sgd:S000002547|dip:DIP-1755N|mint:Q03920|ensemblfungi:YDR140W(gene)|ensemblfungi:YDR140W_mRNA(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006417"(regulation of translation)|go:"GO:0008276"(protein methyltransferase activity)|go:"GO:0008757"(S-adenosylmethionine-dependent methyltransferase activity)|go:"GO:0018364"(peptidyl-glutamine methylation)|go:"GO:0035657"(eRF1 methyltransferase complex)|go:"GO:0102559"("protein-(glutamine-N5) methyltransferase activity")|interpro:IPR002052(N-6 adenine-specific DNA methylase, conserved site)|interpro:IPR004557(Putative methylase)|interpro:IPR007848(Methyltransferase small)|interpro:IPR029063|reactome:R-SCE-156581|reactome:R-SCE-72764|sgd:YDR140W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:QPI15/Fod+FtlArvKKNMPGSu3zQ9606	rogid:pu/ERTe9ojnsy8nxRKkRA+sHq80559292	intact-crc:3A46E64A39154CF1|rigid:XdZxrTaU/RWJjyUcL48LBOGZOr8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O43186	uniprotkb:Q03920	intact:EBI-748171|uniprotkb:Q0QD45|ensembl:ENSP00000221996|ensembl:ENSP00000445565	intact:EBI-31378|uniprotkb:D6VSC3|ensemblfungi:YDR140W	psi-mi:crx_human(display_long)|uniprotkb:CRX(gene name)|psi-mi:CRX(display_short)|uniprotkb:CORD2(gene name synonym)	psi-mi:mtq2_yeast(display_long)|uniprotkb:MTQ2(gene name)|psi-mi:MTQ2(display_short)|uniprotkb:MTC6(gene name synonym)|uniprotkb:"N(5)-glutamine methyltransferase MTQ2"(gene name synonym)|uniprotkb:YDR140W(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11535013|imex:IM-24995-1328	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000545.1|ensembl:ENSG00000105392(gene)|ensembl:ENST00000221996(transcript)|ensembl:ENST00000539067(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007601"(visual perception)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050896"(response to stimulus)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013851(Transcription factor Otx, C-terminal)|interpro:IPR017970|entrezgene/locuslink:1406(identity)	refseq:NP_010424.3|sgd:S000002547|dip:DIP-1755N|mint:Q03920|ensemblfungi:YDR140W(gene)|ensemblfungi:YDR140W_mRNA(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006417"(regulation of translation)|go:"GO:0008276"(protein methyltransferase activity)|go:"GO:0008757"(S-adenosylmethionine-dependent methyltransferase activity)|go:"GO:0018364"(peptidyl-glutamine methylation)|go:"GO:0035657"(eRF1 methyltransferase complex)|go:"GO:0102559"("protein-(glutamine-N5) methyltransferase activity")|interpro:IPR002052(N-6 adenine-specific DNA methylase, conserved site)|interpro:IPR004557(Putative methylase)|interpro:IPR007848(Methyltransferase small)|interpro:IPR029063|reactome:R-SCE-156581|reactome:R-SCE-72764|sgd:YDR140W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:v/bkO/0iLzq1Q2HtieWQQ40RF9M9606	rogid:pu/ERTe9ojnsy8nxRKkRA+sHq80559292	intact-crc:837706C69C5B984C|rigid:jK1E8/cYJFzaXPokj4t5pjA2Fhg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q04110	uniprotkb:P63279	intact:EBI-37150|uniprotkb:D6VT71|ensemblfungi:YDR446W	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	psi-mi:ecm11_yeast(display_long)|uniprotkb:ECM11(gene name)|psi-mi:ECM11(display_short)|uniprotkb:YDR446W(locus name)|uniprotkb:D9461.31(orf name)|uniprotkb:Extracellular mutant protein 11(gene name synonym)	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11535060|imex:IM-24995-1333	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002854|refseq:NP_010734.1|dip:DIP-2060N|ensemblfungi:YDR446W(gene)|ensemblfungi:YDR446W_mRNA(transcript)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0005634"(nucleus)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0070193"(synaptonemal complex organization)|go:"GO:0071555"(cell wall organization)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|interpro:IPR029178|sgd:YDR446W(identity)	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N|entrezgene/locuslink:7329(identity)	-	crc64:CB6890F4EE069232	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:F5ueMuYv+ymWlt2junW3o49OB/g559292	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	intact-crc:4B32FE8141C3EB5A|rigid:PbVxpQjOy6uwNdh04tE2X2XI63A	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q5JST6	uniprotkb:Q04087	intact:EBI-2349927|uniprotkb:Q9H653|uniprotkb:Q5JST8|uniprotkb:Q68DK4|uniprotkb:Q8NEI0|intact:EBI-28971886|ensembl:ENSP00000404232	intact:EBI-32189|uniprotkb:D6VT66|ensemblfungi:YDR439W	psi-mi:efhc2_human(display_long)|uniprotkb:EFHC2(gene name)|psi-mi:EFHC2(display_short)	psi-mi:lrs4_yeast(display_long)|uniprotkb:Loss of rDNA silencing protein 4(gene name synonym)|uniprotkb:LRS4(gene name)|psi-mi:LRS4(display_short)|uniprotkb:D9461.25(orf name)|uniprotkb:YDR439W(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11535051|imex:IM-24995-1332	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000404232|refseq:NP_079460.2|ensembl:ENSG00000183690(gene)|ensembl:ENST00000420999(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005930"(axoneme)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0060285"(cilium-dependent cell motility)|go:"GO:0072686"(mitotic spindle)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR006602(Region of unknown function DM10)|interpro:IPR011992(EF-Hand type)|interpro:IPR040193|rcsb pdb:2Z13|rcsb pdb:2Z14|entrezgene/locuslink:80258(identity)	refseq:NP_010727.1|sgd:S000002847|dip:DIP-1416N|mint:Q04087|ensemblfungi:YDR439W(gene)|ensemblfungi:YDR439W_mRNA(transcript)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0033551"(monopolin complex)|go:"GO:0034503"(protein localization to nucleolar rDNA repeats)|go:"GO:0045143"(homologous chromosome segregation)|go:"GO:0051455"(monopolar spindle attachment to meiosis I kinetochore)|go:"GO:0070550"(rDNA condensation)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|interpro:IPR018479|rcsb pdb:3N7N|sgd:YDR439W(identity)	-	-	crc64:60D880BA947B9005	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:O1XriQSkLcYkk7H7AlanQ1FKIBY9606	rogid:XJ/t2ftZBXOTJshr/zQeMxci/6Q559292	intact-crc:CE80B39266F1D2CF|rigid:G9MVygKpQUyOlAlbHk3FtZJ1nVc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P43356	uniprotkb:Q03981	intact:EBI-5650739|uniprotkb:A8K328|uniprotkb:Q32NC6|ensembl:ENSP00000333487|ensembl:ENSP00000359316|ensembl:ENSP00000469919|ensembl:ENSP00000470872|ensembl:ENSP00000480491|ensembl:ENSP00000480738|ensembl:ENSP00000484290|ensembl:ENSP00000485391|ensembl:ENSP00000485541|ensembl:ENSP00000507594|ensembl:ENSP00000507899	intact:EBI-33535|uniprotkb:D6VSG1|ensemblfungi:YDR179C	psi-mi:maga2_human(display_long)|uniprotkb:MAGEA2(gene name)|psi-mi:MAGEA2(display_short)|uniprotkb:MAGEA2B(gene name)|psi-mi:MAGEA2B(display_short)|uniprotkb:MAGE2(gene name synonym)|uniprotkb:MAGEA2A(gene name synonym)|uniprotkb:MAGE2(gene name synonym)|uniprotkb:MAGEA2(gene name synonym)|uniprotkb:Cancer/testis antigen 1.2(gene name synonym)|uniprotkb:MAGE-2 antigen(gene name synonym)	psi-mi:csn9_yeast(display_long)|uniprotkb:CSN9(gene name)|psi-mi:CSN9(display_short)|uniprotkb:YDR179C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11535042|imex:IM-24995-1331	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001269430.1|refseq:NP_001269431.1|refseq:NP_001269433.1|refseq:NP_001269434.1|refseq:NP_001308329.1|refseq:NP_001308330.1|refseq:NP_001308331.1|refseq:NP_001308332.1|refseq:NP_001308333.1|refseq:NP_005352.1|refseq:NP_705692.1|refseq:NP_786884.1|refseq:NP_786885.1|dip:DIP-61231N|refseq:XP_016884895.1|refseq:XP_016885008.1|ensembl:ENSG00000183305(gene)|ensembl:ENSG00000268606(gene)|ensembl:ENST00000331220(transcript)|ensembl:ENST00000370293(transcript)|ensembl:ENST00000595583(transcript)|ensembl:ENST00000598543(transcript)|ensembl:ENST00000611557(transcript)|ensembl:ENST00000611674(transcript)|ensembl:ENST00000620710(transcript)|ensembl:ENST00000623438(transcript)|ensembl:ENST00000623806(transcript)|ensembl:ENST00000682532(transcript)|ensembl:ENST00000684311(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0016605"(PML body)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0033234"(negative regulation of protein sumoylation)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0044257"(cellular protein catabolic process)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0072331"(signal transduction by p53 class mediator)|go:"GO:0090398"(cellular senescence)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901984"(negative regulation of protein acetylation)|interpro:IPR002190(MAGE protein)|interpro:IPR021072|interpro:IPR030103|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|entrezgene/locuslink:266740(identity)	refseq:NP_010464.1|sgd:S000002586|mint:Q03981|dip:DIP-1580N|ensemblfungi:YDR179C(gene)|ensemblfungi:YDR179C_mRNA(transcript)|go:"GO:0000338"(protein deneddylation)|go:"GO:0000754"(adaptation of signaling pathway by response to pheromone involved in conjugation with cellular fusion)|go:"GO:0005737"(cytoplasm)|go:"GO:0008180"(COP9 signalosome)|interpro:IPR016806(COP9 signalosome complex, subunit 9)|sgd:YDR179C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:aYv4+irEk9vGE2f3yZQR8hCQGec9606	rogid:DHoL1YAXDCBQU4RcLn9kg4T00V0559292	intact-crc:E7D25CA6FBD63165|rigid:DwZKi1PtUD53+blnRvAz8zMYZxk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q03973	uniprotkb:Q0VDD7	intact:EBI-33047|uniprotkb:D6VSF6|ensemblfungi:YDR174W	intact:EBI-741210|ensembl:ENSP00000465822|ensembl:ENSP00000500215|uniprotkb:Q13411|uniprotkb:Q8N825|uniprotkb:Q96D63|uniprotkb:Q9BU49	psi-mi:hmo1_yeast(display_long)|uniprotkb:HMO1(gene name)|psi-mi:HMO1(display_short)|uniprotkb:High spontaneous mutagenesis protein 2(gene name synonym)|uniprotkb:HSM2(gene name synonym)|uniprotkb:YD9395.07(orf name)|uniprotkb:YDR174W(locus name)	psi-mi:brme1_human(display_long)|uniprotkb:BRME1(gene name)|psi-mi:BRME1(display_short)|uniprotkb:C19orf57(gene name synonym)|uniprotkb:Pre-T/NK cell-associated protein 3B3(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11535031|imex:IM-24995-1330	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010459.1|sgd:S000002581|mint:Q03973|dip:DIP-1687N|ensemblfungi:YDR174W(gene)|ensemblfungi:YDR174W_mRNA(transcript)|go:"GO:0000400"(four-way junction DNA binding)|go:"GO:0001174"(transcriptional start site selection at RNA polymerase II promoter)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006265"(DNA topological change)|go:"GO:0006323"(DNA packaging)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006356"(regulation of transcription by RNA polymerase I)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0030261"(chromosome condensation)|go:"GO:0032040"(small-subunit processome)|go:"GO:0033553"(rDNA heterochromatin)|go:"GO:0044804"(autophagy of nucleus)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0060962"(regulation of ribosomal protein gene transcription by RNA polymerase II)|go:"GO:0070550"(rDNA condensation)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR036910|reactome:R-SCE-140342|reactome:R-SCE-5620971|reactome:R-SCE-5686938|reactome:R-SCE-6798695|sgd:YDR174W(identity)	refseq:NP_077299.3|ensembl:ENSG00000132016(gene)|ensembl:ENSG00000288152(gene)|ensembl:ENST00000586783(transcript)|ensembl:ENST00000672170(transcript)|go:"GO:0005694"(chromosome)|go:"GO:0007144"(female meiosis I)|go:"GO:0007275"(multicellular organism development)|go:"GO:0007283"(spermatogenesis)|go:"GO:1990918"(double-strand break repair involved in meiotic recombination)|interpro:IPR031441|refseq:NP_001332773.1|entrezgene/locuslink:79173(identity)	-	crc64:3D6DCD56A28B7D77	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:9sHGPuUbReXRmvQYqKvnd4fWBd4559292	rogid:YUbAjs5ZmWOPWRA9kq5qRZRioR49606	intact-crc:AF2CE99FA7056BAE|rigid:mqvSRvkWXmonNANRgMPSVNi47EY	false	-	sufficient binding region:336-668	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q04264	uniprotkb:Q9P1Z2	intact:EBI-13077|uniprotkb:Q04780|uniprotkb:D6VZQ0|ensemblfungi:YMR076C	intact:EBI-749920|uniprotkb:B3KVA8|uniprotkb:Q6FI59|uniprotkb:Q71RC3|uniprotkb:Q86WF8|uniprotkb:Q96JU3|uniprotkb:Q9H090|intact:EBI-2558801|ensembl:ENSP00000449960	psi-mi:pds5_yeast(display_long)|uniprotkb:PDS5(gene name)|psi-mi:PDS5(display_short)|uniprotkb:YMR076C(locus name)|uniprotkb:YM9916.15C(orf name)|uniprotkb:YM9582.01C(orf name)|uniprotkb:Precocious dissociation of sisters protein 5(gene name synonym)	psi-mi:caco1_human(display_long)|uniprotkb:CALCOCO1(gene name)|psi-mi:CALCOCO1(display_short)|uniprotkb:KIAA1536(gene name synonym)|uniprotkb:Calphoglin(gene name synonym)|uniprotkb:Sarcoma antigen NY-SAR-3(gene name synonym)|uniprotkb:Coiled-coil coactivator protein(gene name synonym)|uniprotkb:PP13275(orf name)|uniprotkb:UNQ2436/PRO4996(orf name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11535105|imex:IM-24995-1338	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013793.1|sgd:S000004681|mint:Q04264|dip:DIP-6799N|ensemblfungi:YMR076C(gene)|ensemblfungi:YMR076C_mRNA(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0035808"(meiotic recombination initiation complex)|go:"GO:0042138"(meiotic DNA double-strand break formation)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0140588"(chromatin looping)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR032682|interpro:IPR039776|rcsb pdb:5FRP|rcsb pdb:5FRR|rcsb pdb:5FRS|reactome:R-SCE-2468052|reactome:R-SCE-2500257|sgd:YMR076C(identity)	refseq:NP_001137154.1|refseq:NP_065949.1|refseq:XP_016875196.1|dip:DIP-47322N|ensembl:ENSG00000012822(gene)|ensembl:ENST00000550804(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0007165"(signal transduction)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0070016"(armadillo repeat domain binding)|interpro:IPR012852(Coiled-coil transcriptional coactivator-like)|interpro:IPR041611|interpro:IPR041641|mint:Q9P1Z2|entrezgene/locuslink:57658(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:JtsuFYTdfc1TRvCvtjuJ8AAHCoU559292	rogid:4M9Qyq+7GZ1w2UAN6k0ntGQNTvw9606	intact-crc:82EA59495C8AF753|rigid:xsK8GEqbD9RUATwoolwsYbSf/uw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q04264	uniprotkb:O95198	intact:EBI-13077|uniprotkb:Q04780|uniprotkb:D6VZQ0|ensemblfungi:YMR076C	intact:EBI-746999|uniprotkb:B2RD18|uniprotkb:Q8N484|uniprotkb:Q8TBH5|uniprotkb:A6NCM7|uniprotkb:B4DFH7|uniprotkb:F5H6M3|ensembl:ENSP00000226725	psi-mi:pds5_yeast(display_long)|uniprotkb:PDS5(gene name)|psi-mi:PDS5(display_short)|uniprotkb:YMR076C(locus name)|uniprotkb:YM9916.15C(orf name)|uniprotkb:YM9582.01C(orf name)|uniprotkb:Precocious dissociation of sisters protein 5(gene name synonym)	psi-mi:klhl2_human(display_long)|uniprotkb:Actin-binding protein Mayven(gene name synonym)|uniprotkb:KLHL2(gene name)|psi-mi:KLHL2(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11535096|imex:IM-24995-1337	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013793.1|sgd:S000004681|mint:Q04264|dip:DIP-6799N|ensemblfungi:YMR076C(gene)|ensemblfungi:YMR076C_mRNA(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0035808"(meiotic recombination initiation complex)|go:"GO:0042138"(meiotic DNA double-strand break formation)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0140588"(chromatin looping)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR032682|interpro:IPR039776|rcsb pdb:5FRP|rcsb pdb:5FRR|rcsb pdb:5FRS|reactome:R-SCE-2468052|reactome:R-SCE-2500257|sgd:YMR076C(identity)	refseq:NP_001154993.1|refseq:NP_001154994.1|refseq:NP_009177.3|refseq:NP_001317952.1|refseq:NP_001317953.1|refseq:XP_016863165.1|ensembl:ENSG00000109466(gene)|ensembl:ENST00000226725(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030027"(lamellipodium)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR017096(Kelch-like protein, gigaxonin)|interpro:IPR044072|mint:O95198|rcsb pdb:2XN4|rcsb pdb:4CHB|reactome:R-HSA-8951664|reactome:R-HSA-983168|go:"GO:0042802"(identical protein binding)|entrezgene/locuslink:11275(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:JtsuFYTdfc1TRvCvtjuJ8AAHCoU559292	rogid:tFegR2lJZccRqs4qUjdT3PNjNnk9606	intact-crc:0CCE5A5B9183F863|rigid:eApCGZd/gWtKLU55u76zojhWfPI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UMX0	uniprotkb:Q04201	intact:EBI-741480|uniprotkb:Q8IXS9|uniprotkb:Q8N2Q3|uniprotkb:Q9H0T8|uniprotkb:Q9H3R4|uniprotkb:Q9HAZ5|intact:EBI-28967608|ensembl:ENSP00000365576|uniprotkb:Q5T6J5|uniprotkb:Q5T6J9|uniprotkb:A0A024R284	intact:EBI-27928|uniprotkb:D6W0I3|ensemblfungi:YML101C	psi-mi:ubql1_human(display_long)|uniprotkb:Protein linking IAP with cytoskeleton 1(gene name synonym)|uniprotkb:UBQLN1(gene name)|psi-mi:UBQLN1(display_short)|uniprotkb:DA41(gene name synonym)|uniprotkb:PLIC1(gene name synonym)	psi-mi:cue4_yeast(display_long)|uniprotkb:YML101C(locus name)|uniprotkb:Coupling of ubiquitin conjugation to ER degradation protein 4(gene name synonym)|uniprotkb:CUE4(gene name)|psi-mi:CUE4(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11535087|imex:IM-24995-1336	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000257468|ensembl:ENSP00000257468|ensembl:ENSP00000365576|ensembl:ENSG00000135018(gene)|ensembl:ENST00000376395(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000502"(proteasome complex)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016235"(aggresome)|go:"GO:0016236"(macroautophagy)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0019900"(kinase binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035973"(aggrephagy)|go:"GO:0042802"(identical protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0097352"(autophagosome maturation)|go:"GO:1901340"(negative regulation of store-operated calcium channel activity)|go:"GO:1902175"(regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)|interpro:IPR000626(Ubiquitin)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR028430|interpro:IPR029071|mint:Q9UMX0|rcsb pdb:2JY5|rcsb pdb:2JY6|rcsb pdb:2KLC|reactome:R-HSA-8856825|refseq:NP_038466.2|refseq:NP_444295.1|dip:DIP-41629N|entrezgene/locuslink:29979(identity)	refseq:NP_013607.1|sgd:S000004568|dip:DIP-4525N|mint:Q04201|ensemblfungi:YML101C(gene)|ensemblfungi:YML101C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR003892(Ubiquitin system component Cue)|sgd:YML101C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:nCFfZbGCTvRYaXhQ4R99XblslvM9606	rogid:NMBJHZbX4/gU01fk4evPDXm/M6w559292	intact-crc:432D80E9380A1CF2|rigid:ZKinB3+wtv/LmQxyK10PpKsDcag	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q04201	uniprotkb:O43765	intact:EBI-27928|uniprotkb:D6W0I3|ensemblfungi:YML101C	intact:EBI-347996|ensembl:ENSP00000221566|ensembl:ENSP00000503397|ensembl:ENSP00000504495|uniprotkb:Q9BTZ9|intact:EBI-1045243|uniprotkb:Q6FIA9|uniprotkb:D6W610	psi-mi:cue4_yeast(display_long)|uniprotkb:YML101C(locus name)|uniprotkb:Coupling of ubiquitin conjugation to ER degradation protein 4(gene name synonym)|uniprotkb:CUE4(gene name)|psi-mi:CUE4(display_short)	psi-mi:sgta_human(display_long)|uniprotkb:SGTA(gene name)|psi-mi:SGTA(display_short)|uniprotkb:SGT(gene name synonym)|uniprotkb:Alpha-SGT(gene name synonym)|uniprotkb:Vpu-binding protein(gene name synonym)|uniprotkb:SGT1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11535078|imex:IM-24995-1335	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013607.1|sgd:S000004568|dip:DIP-4525N|mint:Q04201|ensemblfungi:YML101C(gene)|ensemblfungi:YML101C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR003892(Ubiquitin system component Cue)|sgd:YML101C(identity)	rcsb pdb:4CPG|rcsb pdb:4GOD|rcsb pdb:4GOE|rcsb pdb:4GOF|reactome:R-HSA-9609523|rcsb pdb:2VYI|ensembl:ENSG00000104969(gene)|ensembl:ENST00000221566(transcript)|ensembl:ENST00000676943(transcript)|ensembl:ENST00000677149(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072380"(TRC complex)|go:"GO:0098850"(extrinsic component of synaptic vesicle membrane)|go:"GO:1903070"(negative regulation of ER-associated ubiquitin-dependent protein catabolic process)|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)|go:"GO:1903646"(positive regulation of chaperone-mediated protein folding)|go:"GO:1904288"(BAT3 complex binding)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR032374|mint:O43765|refseq:XP_011526480.1|refseq:NP_003012.1|entrezgene/locuslink:6449(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:NMBJHZbX4/gU01fk4evPDXm/M6w559292	rogid:r/Cyj4UJk/cS8QdrbjhTZMPCigI9606	intact-crc:FF8BEDB354F41C72|rigid:lkUYU9YQdUZyJS+qFXE4avLypoQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96EV8	uniprotkb:Q04110	intact:EBI-465804|uniprotkb:Q5THY3|uniprotkb:Q5THY4|uniprotkb:Q96NV2|intact:EBI-28986386|ensembl:ENSP00000341680|uniprotkb:Q9H0U2|uniprotkb:Q9H3J5|uniprotkb:A8K3V3	intact:EBI-37150|uniprotkb:D6VT71|ensemblfungi:YDR446W	psi-mi:dtbp1_human(display_long)|uniprotkb:My031(orf name)|uniprotkb:DTNBP1(gene name)|psi-mi:DTNBP1(display_short)|uniprotkb:Dystrobrevin-binding protein 1(gene name synonym)|uniprotkb:Hermansky-Pudlak syndrome 7 protein(gene name synonym)|uniprotkb:Dysbindin-1(gene name synonym)|uniprotkb:BLOC1S8(gene name synonym)|uniprotkb:Biogenesis of lysosome-related organelles complex 1 subunit 8(gene name synonym)	psi-mi:ecm11_yeast(display_long)|uniprotkb:ECM11(gene name)|psi-mi:ECM11(display_short)|uniprotkb:YDR446W(locus name)|uniprotkb:D9461.31(orf name)|uniprotkb:Extracellular mutant protein 11(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11535069|imex:IM-24995-1334	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000047579(gene)|ensembl:ENST00000344537(transcript)|go:"GO:0001956"(positive regulation of neurotransmitter secretion)|go:"GO:0005634"(nucleus)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007596"(blood coagulation)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014059"(regulation of dopamine secretion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016528"(sarcoplasm)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0030496"(midbody)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032438"(melanosome organization)|go:"GO:0033162"(melanosome membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0043005"(neuron projection)|go:"GO:0043197"(dendritic spine)|go:"GO:0005737"(cytoplasm)|go:"GO:0043506"(regulation of JUN kinase activity)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0060155"(platelet dense granule organization)|go:"GO:0060159"(regulation of dopamine receptor signaling pathway)|go:"GO:0071901"(negative regulation of protein serine/threonine kinase activity)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR007531(Dysbindin)|reactome:R-HSA-432722|go:"GO:0048490"(anterograde synaptic vesicle transport)|refseq:NP_115498.2|refseq:NP_898861.1|refseq:NP_001258597.1|refseq:NP_001258598.1|ensembl:ENST00000338950|ensembl:ENSP00000344718|ensembl:ENSP00000341680|refseq:NP_001258596.1|entrezgene/locuslink:84062(identity)	sgd:S000002854|refseq:NP_010734.1|dip:DIP-2060N|ensemblfungi:YDR446W(gene)|ensemblfungi:YDR446W_mRNA(transcript)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0005634"(nucleus)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0070193"(synaptonemal complex organization)|go:"GO:0071555"(cell wall organization)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|interpro:IPR029178|sgd:YDR446W(identity)	-	-	crc64:CB6890F4EE069232	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:PBwxp1vobm9l5yGoqev97lzkMHg9606	rogid:F5ueMuYv+ymWlt2junW3o49OB/g559292	intact-crc:4B2A5BEBBAED3DB5|rigid:eqNiwv+OLd0YenZ8twdCDnpnE6U	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q04307	uniprotkb:P32321	intact:EBI-15858|uniprotkb:Q2VQW5|ensemblfungi:YDR045C|uniprotkb:D6VS33	intact:EBI-739870|uniprotkb:Q9BVD8|uniprotkb:B2R836|uniprotkb:Q5M7Z8|uniprotkb:D3DP49|uniprotkb:D3DP50|ensembl:ENSP00000398194|ensembl:ENSP00000424017	psi-mi:rpc10_yeast(display_long)|uniprotkb:RPC11(gene name)|psi-mi:RPC11(display_short)|uniprotkb:YDR045C(locus name)|uniprotkb:YD9609.01C(orf name)|uniprotkb:RNA polymerase III subunit C11(gene name synonym)|uniprotkb:DNA-directed RNA polymerases III 12.5 kDa polypeptide(gene name synonym)	psi-mi:dctd_human(display_long)|uniprotkb:DCTD(gene name)|psi-mi:DCTD(display_short)|uniprotkb:dCMP deaminase(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11535143|imex:IM-24995-1342	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YDR045C(gene)|refseq:NP_010330.1|sgd:S000002452|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006386"(termination of RNA polymerase III transcription)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042779"(tRNA 3'-trailer cleavage)|go:"GO:0042797"(tRNA transcription by RNA polymerase III)|interpro:IPR001222(Zinc finger, TFIIS-type)|interpro:IPR001529(DNA-directed RNA polymerase, M/15 kDa subunit)|interpro:IPR012164(DNA-directed RNA polymerase, subunit C11/M/9)|interpro:IPR019761|interpro:IPR034014|rcsb pdb:3QT1|ensemblfungi:YDR045C_mRNA(transcript)|rcsb pdb:5FJ8|rcsb pdb:5FJ9|rcsb pdb:5FJA|rcsb pdb:6CNB|rcsb pdb:6CNC|rcsb pdb:6CND|rcsb pdb:6CNF|rcsb pdb:6EU0|rcsb pdb:6EU2|rcsb pdb:6EU3|rcsb pdb:6F40|rcsb pdb:6F41|rcsb pdb:6F42|rcsb pdb:6F44|rcsb pdb:6TUT|reactome:R-SCE-76061|reactome:R-SCE-76066|rcsb pdb:6EU1|dip:DIP-887N|mint:Q04307|sgd:YDR045C(identity)	refseq:NP_001012750.1|refseq:NP_001912.2|ensembl:ENSG00000129187(gene)|ensembl:ENST00000438320(transcript)|ensembl:ENST00000510370(transcript)|go:"GO:0004132"(dCMP deaminase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006220"(pyrimidine nucleotide metabolic process)|go:"GO:0006226"(dUMP biosynthetic process)|go:"GO:0006231"(dTMP biosynthetic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR002125(CMP/dCMP deaminase, zinc-binding)|interpro:IPR015517(Cytidine deaminase)|interpro:IPR016192(APOBEC/CMP deaminase, zinc-binding)|interpro:IPR016193(Cytidine deaminase-like)|interpro:IPR016473(dCMP deaminase)|interpro:IPR035105|mint:P32321|rcsb pdb:2W4L|reactome:R-HSA-499943|refseq:XP_005262836.1|refseq:XP_005262837.1|refseq:XP_011529976.1|refseq:XP_016863305.1|refseq:XP_016863306.1|refseq:XP_016863307.1|refseq:XP_016863308.1|refseq:XP_016863309.1|refseq:XP_016863310.1|refseq:XP_016863311.1|entrezgene/locuslink:1635(identity)	-	crc64:E4AA802EC9F92230	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:G2fIQbptabHIUI224iPtTJF+dIs559292	rogid:lU3gEi7XdIJbuPlMkForbVKEOyY9606	intact-crc:84321A64394F252E|rigid:C+v6NwAw2T/AZMrpbmOP+ZTq6cI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q04307	uniprotkb:O94993	intact:EBI-15858|uniprotkb:Q2VQW5|ensemblfungi:YDR045C|uniprotkb:D6VS33	intact:EBI-742973|ensembl:ENSP00000265007|uniprotkb:O94995|uniprotkb:Q8IYX6	psi-mi:rpc10_yeast(display_long)|uniprotkb:RPC11(gene name)|psi-mi:RPC11(display_short)|uniprotkb:YDR045C(locus name)|uniprotkb:YD9609.01C(orf name)|uniprotkb:RNA polymerase III subunit C11(gene name synonym)|uniprotkb:DNA-directed RNA polymerases III 12.5 kDa polypeptide(gene name synonym)	psi-mi:sox30_human(display_long)|uniprotkb:SOX30(gene name)|psi-mi:SOX30(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11535134|imex:IM-24995-1341	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YDR045C(gene)|refseq:NP_010330.1|sgd:S000002452|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006386"(termination of RNA polymerase III transcription)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042779"(tRNA 3'-trailer cleavage)|go:"GO:0042797"(tRNA transcription by RNA polymerase III)|interpro:IPR001222(Zinc finger, TFIIS-type)|interpro:IPR001529(DNA-directed RNA polymerase, M/15 kDa subunit)|interpro:IPR012164(DNA-directed RNA polymerase, subunit C11/M/9)|interpro:IPR019761|interpro:IPR034014|rcsb pdb:3QT1|ensemblfungi:YDR045C_mRNA(transcript)|rcsb pdb:5FJ8|rcsb pdb:5FJ9|rcsb pdb:5FJA|rcsb pdb:6CNB|rcsb pdb:6CNC|rcsb pdb:6CND|rcsb pdb:6CNF|rcsb pdb:6EU0|rcsb pdb:6EU2|rcsb pdb:6EU3|rcsb pdb:6F40|rcsb pdb:6F41|rcsb pdb:6F42|rcsb pdb:6F44|rcsb pdb:6TUT|reactome:R-SCE-76061|reactome:R-SCE-76066|rcsb pdb:6EU1|dip:DIP-887N|mint:Q04307|sgd:YDR045C(identity)	rcsb pdb:7JJK|refseq:NP_008948.1|refseq:NP_848511.1|ensembl:ENSG00000039600(gene)|ensembl:ENST00000265007(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007286"(spermatid development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0010369"(chromocenter)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0031960"(response to corticosteroid)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0120211"(proacrosomal vesicle fusion)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR036910|refseq:NP_001295094.1|entrezgene/locuslink:11063(identity)	-	crc64:E4AA802EC9F92230	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:G2fIQbptabHIUI224iPtTJF+dIs559292	rogid:AriyqffK8zuvudW4qjQ9SvnA0Vg9606	intact-crc:921E65519E38F533|rigid:xzx0s+fgkwgoNfQYRTGCdsfHnvo	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q04307	uniprotkb:Q7Z6G3-2	intact:EBI-15858|uniprotkb:Q2VQW5|ensemblfungi:YDR045C|uniprotkb:D6VS33	intact:EBI-10172876|ensembl:ENSP00000457354|intact:EBI-14062040	psi-mi:rpc10_yeast(display_long)|uniprotkb:RPC11(gene name)|psi-mi:RPC11(display_short)|uniprotkb:YDR045C(locus name)|uniprotkb:YD9609.01C(orf name)|uniprotkb:RNA polymerase III subunit C11(gene name synonym)|uniprotkb:DNA-directed RNA polymerases III 12.5 kDa polypeptide(gene name synonym)	psi-mi:q7z6g3-2(display_long)|uniprotkb:EFCBP2(gene name synonym)|uniprotkb:Neuronal calcium-binding protein 2(gene name synonym)|uniprotkb:Synaptotagmin-interacting protein 2(gene name synonym)|uniprotkb:NECAB2(gene name)|psi-mi:NECAB2(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11535123|imex:IM-24995-1340	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YDR045C(gene)|refseq:NP_010330.1|sgd:S000002452|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006386"(termination of RNA polymerase III transcription)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042779"(tRNA 3'-trailer cleavage)|go:"GO:0042797"(tRNA transcription by RNA polymerase III)|interpro:IPR001222(Zinc finger, TFIIS-type)|interpro:IPR001529(DNA-directed RNA polymerase, M/15 kDa subunit)|interpro:IPR012164(DNA-directed RNA polymerase, subunit C11/M/9)|interpro:IPR019761|interpro:IPR034014|rcsb pdb:3QT1|ensemblfungi:YDR045C_mRNA(transcript)|rcsb pdb:5FJ8|rcsb pdb:5FJ9|rcsb pdb:5FJA|rcsb pdb:6CNB|rcsb pdb:6CNC|rcsb pdb:6CND|rcsb pdb:6CNF|rcsb pdb:6EU0|rcsb pdb:6EU2|rcsb pdb:6EU3|rcsb pdb:6F40|rcsb pdb:6F41|rcsb pdb:6F42|rcsb pdb:6F44|rcsb pdb:6TUT|reactome:R-SCE-76061|reactome:R-SCE-76066|rcsb pdb:6EU1|dip:DIP-887N|mint:Q04307|sgd:YDR045C(identity)	ensembl:ENSG00000103154(gene)|ensembl:ENST00000565691(transcript)|uniprotkb:Q7Z6G3-2(isoform-parent)|intact:EBI-950070(isoform-parent)|entrezgene/locuslink:54550(identity)	-	crc64:E4AA802EC9F92230	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:G2fIQbptabHIUI224iPtTJF+dIs559292	rogid:4S7oIx6h+mKzV3EPxqcfMNqaNko9606	intact-crc:9AF14B3388DD05F5|rigid:Um+HMOYZtBTpcWmb37no39hEDIw	false	-	sufficient binding region:65-303	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96H20	uniprotkb:Q04272	intact:EBI-747719|uniprotkb:Q8IXY3|uniprotkb:Q9UN50|ensembl:ENSP00000421380	intact:EBI-28157|uniprotkb:D6VZQ1|ensemblfungi:YMR077C	psi-mi:snf8_human(display_long)|uniprotkb:ELL-associated protein of 30 kDa(gene name synonym)|uniprotkb:SNF8(gene name)|psi-mi:SNF8(display_short)|uniprotkb:EAP30(gene name synonym)|uniprotkb:ESCRT-II complex subunit VPS22(gene name synonym)	psi-mi:vps20_yeast(display_long)|uniprotkb:ASI10(gene name synonym)|uniprotkb:CHM6(gene name synonym)|uniprotkb:VPT20(gene name synonym)|uniprotkb:YM9582.02C(orf name)|uniprotkb:YMR077C(locus name)|uniprotkb:VPS20(gene name)|psi-mi:VPS20(display_short)|uniprotkb:Vacuolar protein-targeting protein 20(gene name synonym)|uniprotkb:Amino acid sensor-independent protein 10(gene name synonym)|uniprotkb:Charged multivesicular body protein 6(gene name synonym)|uniprotkb:ESCRT-III complex subunit VPS20(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11535114|imex:IM-24995-1339	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009172.2|refseq:NP_001304121.1|refseq:NP_001304122.1|refseq:NP_001304123.1|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010008"(endosome membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0016247"(channel regulator activity)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043328"(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055037"(recycling endosome)|go:"GO:0061635"(regulation of protein complex stability)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071985"(multivesicular body sorting pathway)|go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:1903772"(regulation of viral budding via host ESCRT complex)|interpro:IPR016689(ESCRT-2 complex, Snf8)|interpro:IPR036388|interpro:IPR036390|interpro:IPR040608|mint:Q96H20|rcsb pdb:2ZME|rcsb pdb:3CUQ|reactome:R-HSA-917729|reactome:R-HSA-9610379|ensembl:ENSG00000159210(gene)|ensembl:ENST00000502492(transcript)|go:"GO:0000814"(ESCRT II complex)|entrezgene/locuslink:11267(identity)	reactome:R-SCE-1632852|refseq:NP_013794.1|sgd:S000004682|dip:DIP-1961N|reactome:R-SCE-917729|reactome:R-SCE-9668328|ensemblfungi:YMR077C(gene)|ensemblfungi:YMR077C_mRNA(transcript)|go:"GO:0000815"(ESCRT III complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005771"(multivesicular body)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0015031"(protein transport)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0070676"(intralumenal vesicle formation)|go:"GO:1904669"(ATP export)|interpro:IPR005024(Snf7)|rcsb pdb:5FVL|sgd:YMR077C(identity)	-	-	crc64:CDC88BC4ADA3D602	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:FyjlBpOt9okBFV8Z+g8YLUeyCm49606	rogid:K6P+RVrruRMbHsMdRoH/v0f+0Z0559292	intact-crc:96DFF35BDB44D2E5|rigid:Z6nSM53uGs9aFz1mYDvVCNl7R4w	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q04307	uniprotkb:Q6P1W5	intact:EBI-15858|uniprotkb:Q2VQW5|ensemblfungi:YDR045C|uniprotkb:D6VS33	intact:EBI-946029|uniprotkb:B3KVT1|uniprotkb:Q96IC8|ensembl:ENSP00000435634|uniprotkb:D3DPR3|uniprotkb:E9PJ76	psi-mi:rpc10_yeast(display_long)|uniprotkb:RPC11(gene name)|psi-mi:RPC11(display_short)|uniprotkb:YDR045C(locus name)|uniprotkb:YD9609.01C(orf name)|uniprotkb:RNA polymerase III subunit C11(gene name synonym)|uniprotkb:DNA-directed RNA polymerases III 12.5 kDa polypeptide(gene name synonym)	psi-mi:ca094_human(display_long)|uniprotkb:C1orf94(gene name)|psi-mi:C1orf94(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11535170|imex:IM-24995-1345	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YDR045C(gene)|refseq:NP_010330.1|sgd:S000002452|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006386"(termination of RNA polymerase III transcription)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042779"(tRNA 3'-trailer cleavage)|go:"GO:0042797"(tRNA transcription by RNA polymerase III)|interpro:IPR001222(Zinc finger, TFIIS-type)|interpro:IPR001529(DNA-directed RNA polymerase, M/15 kDa subunit)|interpro:IPR012164(DNA-directed RNA polymerase, subunit C11/M/9)|interpro:IPR019761|interpro:IPR034014|rcsb pdb:3QT1|ensemblfungi:YDR045C_mRNA(transcript)|rcsb pdb:5FJ8|rcsb pdb:5FJ9|rcsb pdb:5FJA|rcsb pdb:6CNB|rcsb pdb:6CNC|rcsb pdb:6CND|rcsb pdb:6CNF|rcsb pdb:6EU0|rcsb pdb:6EU2|rcsb pdb:6EU3|rcsb pdb:6F40|rcsb pdb:6F41|rcsb pdb:6F42|rcsb pdb:6F44|rcsb pdb:6TUT|reactome:R-SCE-76061|reactome:R-SCE-76066|rcsb pdb:6EU1|dip:DIP-887N|mint:Q04307|sgd:YDR045C(identity)	refseq:NP_001128206.1|refseq:NP_116273.2|ensembl:ENSG00000142698(gene)|ensembl:ENST00000488417(transcript)|interpro:IPR031496|entrezgene/locuslink:84970(identity)	-	crc64:E4AA802EC9F92230	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:G2fIQbptabHIUI224iPtTJF+dIs559292	rogid:y1o4xWvTl2CBA1J7jsP7y8ZjLzM9606	intact-crc:A6CD4A45741923FC|rigid:lAblKOzNr1tiUBq1jkBoEwAh1X0	false	-	sufficient binding region:191-598	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q04307	uniprotkb:Q15645	intact:EBI-15858|uniprotkb:Q2VQW5|ensemblfungi:YDR045C|uniprotkb:D6VS33	intact:EBI-358993|uniprotkb:C9K0T3|uniprotkb:O15324|ensembl:ENSP00000166345|uniprotkb:D3DTC0	psi-mi:rpc10_yeast(display_long)|uniprotkb:RPC11(gene name)|psi-mi:RPC11(display_short)|uniprotkb:YDR045C(locus name)|uniprotkb:YD9609.01C(orf name)|uniprotkb:RNA polymerase III subunit C11(gene name synonym)|uniprotkb:DNA-directed RNA polymerases III 12.5 kDa polypeptide(gene name synonym)	psi-mi:pch2_human(display_long)|uniprotkb:TRIP13(gene name)|psi-mi:TRIP13(display_short)|uniprotkb:Thyroid receptor-interacting protein 13(gene name synonym)|uniprotkb:PCH2(gene name synonym)|uniprotkb:Thyroid hormone receptor interactor 13(gene name synonym)|uniprotkb:Human papillomavirus type 16 E1 protein-binding protein(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11535161|imex:IM-24995-1344	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YDR045C(gene)|refseq:NP_010330.1|sgd:S000002452|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006386"(termination of RNA polymerase III transcription)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042779"(tRNA 3'-trailer cleavage)|go:"GO:0042797"(tRNA transcription by RNA polymerase III)|interpro:IPR001222(Zinc finger, TFIIS-type)|interpro:IPR001529(DNA-directed RNA polymerase, M/15 kDa subunit)|interpro:IPR012164(DNA-directed RNA polymerase, subunit C11/M/9)|interpro:IPR019761|interpro:IPR034014|rcsb pdb:3QT1|ensemblfungi:YDR045C_mRNA(transcript)|rcsb pdb:5FJ8|rcsb pdb:5FJ9|rcsb pdb:5FJA|rcsb pdb:6CNB|rcsb pdb:6CNC|rcsb pdb:6CND|rcsb pdb:6CNF|rcsb pdb:6EU0|rcsb pdb:6EU2|rcsb pdb:6EU3|rcsb pdb:6F40|rcsb pdb:6F41|rcsb pdb:6F42|rcsb pdb:6F44|rcsb pdb:6TUT|reactome:R-SCE-76061|reactome:R-SCE-76066|rcsb pdb:6EU1|dip:DIP-887N|mint:Q04307|sgd:YDR045C(identity)	refseq:NP_004228.1|ensembl:ENSG00000071539(gene)|ensembl:ENST00000166345(transcript)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|refseq:XP_011512465.1|dip:DIP-34493N|go:"GO:0005694"(chromosome)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0007141"(male meiosis I)|go:"GO:0007144"(female meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007286"(spermatid development)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051598"(meiotic recombination checkpoint signaling)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR027417|interpro:IPR044539|mint:Q15645|rcsb pdb:5VQ9|rcsb pdb:5VQA|rcsb pdb:5WC2|rcsb pdb:6F0X|rcsb pdb:6LK0|rcsb pdb:7L9P|entrezgene/locuslink:9319(identity)	-	crc64:E4AA802EC9F92230	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:G2fIQbptabHIUI224iPtTJF+dIs559292	rogid:heF2f3R2lGIpZ80mZHnhMktXTE49606	intact-crc:E70B8B44E281A565|rigid:xjGEbc9I5sNUM3H74oZtdRfa8/k	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q04307	uniprotkb:Q13422-7	intact:EBI-15858|uniprotkb:Q2VQW5|ensemblfungi:YDR045C|uniprotkb:D6VS33	intact:EBI-11522367|ensembl:ENSP00000352123|ensembl:ENSP00000413025	psi-mi:rpc10_yeast(display_long)|uniprotkb:RPC11(gene name)|psi-mi:RPC11(display_short)|uniprotkb:YDR045C(locus name)|uniprotkb:YD9609.01C(orf name)|uniprotkb:RNA polymerase III subunit C11(gene name synonym)|uniprotkb:DNA-directed RNA polymerases III 12.5 kDa polypeptide(gene name synonym)	psi-mi:q13422-7(display_long)|uniprotkb:IKZF1(gene name)|psi-mi:IKZF1(display_short)|uniprotkb:IK1(gene name synonym)|uniprotkb:IKAROS(gene name synonym)|uniprotkb:Ikaros family zinc finger protein 1(gene name synonym)|uniprotkb:LYF1(gene name synonym)|uniprotkb:Lymphoid transcription factor LyF-1(gene name synonym)|uniprotkb:ZNFN1A1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11535152|imex:IM-24995-1343	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YDR045C(gene)|refseq:NP_010330.1|sgd:S000002452|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006386"(termination of RNA polymerase III transcription)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042779"(tRNA 3'-trailer cleavage)|go:"GO:0042797"(tRNA transcription by RNA polymerase III)|interpro:IPR001222(Zinc finger, TFIIS-type)|interpro:IPR001529(DNA-directed RNA polymerase, M/15 kDa subunit)|interpro:IPR012164(DNA-directed RNA polymerase, subunit C11/M/9)|interpro:IPR019761|interpro:IPR034014|rcsb pdb:3QT1|ensemblfungi:YDR045C_mRNA(transcript)|rcsb pdb:5FJ8|rcsb pdb:5FJ9|rcsb pdb:5FJA|rcsb pdb:6CNB|rcsb pdb:6CNC|rcsb pdb:6CND|rcsb pdb:6CNF|rcsb pdb:6EU0|rcsb pdb:6EU2|rcsb pdb:6EU3|rcsb pdb:6F40|rcsb pdb:6F41|rcsb pdb:6F42|rcsb pdb:6F44|rcsb pdb:6TUT|reactome:R-SCE-76061|reactome:R-SCE-76066|rcsb pdb:6EU1|dip:DIP-887N|mint:Q04307|sgd:YDR045C(identity)	intact:EBI-745305(isoform-parent)|ensembl:ENSG00000185811(gene)|ensembl:ENST00000359197(transcript)|ensembl:ENST00000439701(transcript)|uniprotkb:Q13422-7(isoform-parent)|entrezgene/locuslink:10320(identity)	-	crc64:E4AA802EC9F92230	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:G2fIQbptabHIUI224iPtTJF+dIs559292	rogid:ou/ovXYoMneBNVp4pj38VxenfyY9606	intact-crc:739C356ACDCE6842|rigid:AguOrpXzwc0g3NAN036O7vb92XI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q04307	uniprotkb:Q8ND30	intact:EBI-15858|uniprotkb:Q2VQW5|ensemblfungi:YDR045C|uniprotkb:D6VS33	intact:EBI-744056|uniprotkb:O75337|uniprotkb:Q8WW26|intact:EBI-28975311|uniprotkb:B7Z433|uniprotkb:E9PK77|ensembl:ENSP00000299492	psi-mi:rpc10_yeast(display_long)|uniprotkb:RPC11(gene name)|psi-mi:RPC11(display_short)|uniprotkb:YDR045C(locus name)|uniprotkb:YD9609.01C(orf name)|uniprotkb:RNA polymerase III subunit C11(gene name synonym)|uniprotkb:DNA-directed RNA polymerases III 12.5 kDa polypeptide(gene name synonym)	psi-mi:lipb2_human(display_long)|uniprotkb:Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 2(gene name synonym)|uniprotkb:PPFIBP2(gene name)|psi-mi:PPFIBP2(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11535203|imex:IM-24995-1348	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YDR045C(gene)|refseq:NP_010330.1|sgd:S000002452|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006386"(termination of RNA polymerase III transcription)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042779"(tRNA 3'-trailer cleavage)|go:"GO:0042797"(tRNA transcription by RNA polymerase III)|interpro:IPR001222(Zinc finger, TFIIS-type)|interpro:IPR001529(DNA-directed RNA polymerase, M/15 kDa subunit)|interpro:IPR012164(DNA-directed RNA polymerase, subunit C11/M/9)|interpro:IPR019761|interpro:IPR034014|rcsb pdb:3QT1|ensemblfungi:YDR045C_mRNA(transcript)|rcsb pdb:5FJ8|rcsb pdb:5FJ9|rcsb pdb:5FJA|rcsb pdb:6CNB|rcsb pdb:6CNC|rcsb pdb:6CND|rcsb pdb:6CNF|rcsb pdb:6EU0|rcsb pdb:6EU2|rcsb pdb:6EU3|rcsb pdb:6F40|rcsb pdb:6F41|rcsb pdb:6F42|rcsb pdb:6F44|rcsb pdb:6TUT|reactome:R-SCE-76061|reactome:R-SCE-76066|rcsb pdb:6EU1|dip:DIP-887N|mint:Q04307|sgd:YDR045C(identity)	refseq:NP_003612.2|ensembl:ENSP00000299492|ensembl:ENST00000528883|ensembl:ENSP00000435469|ensembl:ENST00000530181|ensembl:ENSP00000437321|refseq:NP_001243497.1|refseq:XP_016873932.1|dip:DIP-42373N|ensembl:ENSG00000166387(gene)|ensembl:ENST00000299492(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0042802"(identical protein binding)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0050808"(synapse organization)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR029515|interpro:IPR030435|interpro:IPR037617|interpro:IPR037618|interpro:IPR037619|mint:Q8ND30|rcsb pdb:3QH9|reactome:R-HSA-388844|entrezgene/locuslink:8495(identity)	-	crc64:E4AA802EC9F92230	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:G2fIQbptabHIUI224iPtTJF+dIs559292	rogid:36bMLWHJuGN5eItyc1HvhoLonZA9606	intact-crc:041538F87E33E0B5|rigid:Q9dj5jef7/lx/22Iu6UUYIJH55M	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8N7W2-2	uniprotkb:Q04307	intact:EBI-10181188|ensembl:ENSP00000367868	intact:EBI-15858|uniprotkb:Q2VQW5|ensemblfungi:YDR045C|uniprotkb:D6VS33	psi-mi:q8n7w2-2(display_long)|uniprotkb:C10orf30(gene name synonym)|uniprotkb:BEND7(gene name)|psi-mi:BEND7(display_short)	psi-mi:rpc10_yeast(display_long)|uniprotkb:RPC11(gene name)|psi-mi:RPC11(display_short)|uniprotkb:YDR045C(locus name)|uniprotkb:YD9609.01C(orf name)|uniprotkb:RNA polymerase III subunit C11(gene name synonym)|uniprotkb:DNA-directed RNA polymerases III 12.5 kDa polypeptide(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11535192|imex:IM-24995-1347	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000165626(gene)|ensembl:ENST00000378605(transcript)|intact:EBI-743382(isoform-parent)|uniprotkb:Q8N7W2-2(isoform-parent)|entrezgene/locuslink:222389(identity)	ensemblfungi:YDR045C(gene)|refseq:NP_010330.1|sgd:S000002452|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006386"(termination of RNA polymerase III transcription)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042779"(tRNA 3'-trailer cleavage)|go:"GO:0042797"(tRNA transcription by RNA polymerase III)|interpro:IPR001222(Zinc finger, TFIIS-type)|interpro:IPR001529(DNA-directed RNA polymerase, M/15 kDa subunit)|interpro:IPR012164(DNA-directed RNA polymerase, subunit C11/M/9)|interpro:IPR019761|interpro:IPR034014|rcsb pdb:3QT1|ensemblfungi:YDR045C_mRNA(transcript)|rcsb pdb:5FJ8|rcsb pdb:5FJ9|rcsb pdb:5FJA|rcsb pdb:6CNB|rcsb pdb:6CNC|rcsb pdb:6CND|rcsb pdb:6CNF|rcsb pdb:6EU0|rcsb pdb:6EU2|rcsb pdb:6EU3|rcsb pdb:6F40|rcsb pdb:6F41|rcsb pdb:6F42|rcsb pdb:6F44|rcsb pdb:6TUT|reactome:R-SCE-76061|reactome:R-SCE-76066|rcsb pdb:6EU1|dip:DIP-887N|mint:Q04307|sgd:YDR045C(identity)	-	-	crc64:E4AA802EC9F92230	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:p6qrTn80hLyVU0W2Tvwn50Q4m5I9606	rogid:G2fIQbptabHIUI224iPtTJF+dIs559292	intact-crc:FB508E679F4967CD|rigid:9adlJDrnegjPAP7J4eGktnx2ZJI	false	sufficient binding region:10-374	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8IYA8	uniprotkb:Q04307	intact:EBI-8638439|intact:EBI-28969497|ensembl:ENSP00000296449|ensembl:ENSP00000391788|ensembl:ENSP00000407837|uniprotkb:C9JJL0|uniprotkb:Q96LP7|intact:MINT-8162095|uniprotkb:Q05DG9	intact:EBI-15858|uniprotkb:Q2VQW5|ensemblfungi:YDR045C|uniprotkb:D6VS33	psi-mi:iho1_human(display_long)|uniprotkb:IHO1(gene name)|psi-mi:IHO1(display_short)|uniprotkb:CCDC36(gene name synonym)|uniprotkb:Cancer/testis antigen 74(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 36(gene name synonym)	psi-mi:rpc10_yeast(display_long)|uniprotkb:RPC11(gene name)|psi-mi:RPC11(display_short)|uniprotkb:YDR045C(locus name)|uniprotkb:YD9609.01C(orf name)|uniprotkb:RNA polymerase III subunit C11(gene name synonym)|uniprotkb:DNA-directed RNA polymerases III 12.5 kDa polypeptide(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11535181|imex:IM-24995-1346	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000296449|ensembl:ENST00000366429|ensembl:ENSP00000403700|ensembl:ENSP00000391788|ensembl:ENSP00000407837|ensembl:ENSG00000173421(gene)|ensembl:ENST00000296449(transcript)|ensembl:ENST00000438782(transcript)|ensembl:ENST00000452691(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0006310"(DNA recombination)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0042138"(meiotic DNA double-strand break formation)|go:"GO:0048477"(oogenesis)|go:"GO:0060629"(regulation of homologous chromosome segregation)|interpro:IPR031529|mint:Q8IYA8|refseq:XP_011531974.1|refseq:XP_011531975.1|refseq:NP_001128669.1|refseq:NP_835467.2|refseq:XP_006713187.1|entrezgene/locuslink:339834(identity)	ensemblfungi:YDR045C(gene)|refseq:NP_010330.1|sgd:S000002452|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006386"(termination of RNA polymerase III transcription)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042779"(tRNA 3'-trailer cleavage)|go:"GO:0042797"(tRNA transcription by RNA polymerase III)|interpro:IPR001222(Zinc finger, TFIIS-type)|interpro:IPR001529(DNA-directed RNA polymerase, M/15 kDa subunit)|interpro:IPR012164(DNA-directed RNA polymerase, subunit C11/M/9)|interpro:IPR019761|interpro:IPR034014|rcsb pdb:3QT1|ensemblfungi:YDR045C_mRNA(transcript)|rcsb pdb:5FJ8|rcsb pdb:5FJ9|rcsb pdb:5FJA|rcsb pdb:6CNB|rcsb pdb:6CNC|rcsb pdb:6CND|rcsb pdb:6CNF|rcsb pdb:6EU0|rcsb pdb:6EU2|rcsb pdb:6EU3|rcsb pdb:6F40|rcsb pdb:6F41|rcsb pdb:6F42|rcsb pdb:6F44|rcsb pdb:6TUT|reactome:R-SCE-76061|reactome:R-SCE-76066|rcsb pdb:6EU1|dip:DIP-887N|mint:Q04307|sgd:YDR045C(identity)	-	comment:mint	crc64:E4AA802EC9F92230	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:+TNQLExkhmC1NWqsE240Cx7zFVU9606	rogid:G2fIQbptabHIUI224iPtTJF+dIs559292	intact-crc:DF9BB1EAB95DCCBD|rigid:LjCxaMqrV6DJwAVZcb9AK1ol74s	false	sufficient binding region:11-594	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q04307	uniprotkb:Q9UJW9	intact:EBI-15858|uniprotkb:Q2VQW5|ensemblfungi:YDR045C|uniprotkb:D6VS33	intact:EBI-748621|uniprotkb:Q96CQ2|uniprotkb:B3KQB3|ensembl:ENSP00000325414|ensembl:ENSP00000375882	psi-mi:rpc10_yeast(display_long)|uniprotkb:RPC11(gene name)|psi-mi:RPC11(display_short)|uniprotkb:YDR045C(locus name)|uniprotkb:YD9609.01C(orf name)|uniprotkb:RNA polymerase III subunit C11(gene name synonym)|uniprotkb:DNA-directed RNA polymerases III 12.5 kDa polypeptide(gene name synonym)	psi-mi:srtd3_human(display_long)|uniprotkb:Replication protein-binding trans-activator(gene name synonym)|uniprotkb:SERTAD3(gene name)|psi-mi:SERTAD3(display_short)|uniprotkb:RBT1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11535243|imex:IM-24995-1352	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YDR045C(gene)|refseq:NP_010330.1|sgd:S000002452|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006386"(termination of RNA polymerase III transcription)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042779"(tRNA 3'-trailer cleavage)|go:"GO:0042797"(tRNA transcription by RNA polymerase III)|interpro:IPR001222(Zinc finger, TFIIS-type)|interpro:IPR001529(DNA-directed RNA polymerase, M/15 kDa subunit)|interpro:IPR012164(DNA-directed RNA polymerase, subunit C11/M/9)|interpro:IPR019761|interpro:IPR034014|rcsb pdb:3QT1|ensemblfungi:YDR045C_mRNA(transcript)|rcsb pdb:5FJ8|rcsb pdb:5FJ9|rcsb pdb:5FJA|rcsb pdb:6CNB|rcsb pdb:6CNC|rcsb pdb:6CND|rcsb pdb:6CNF|rcsb pdb:6EU0|rcsb pdb:6EU2|rcsb pdb:6EU3|rcsb pdb:6F40|rcsb pdb:6F41|rcsb pdb:6F42|rcsb pdb:6F44|rcsb pdb:6TUT|reactome:R-SCE-76061|reactome:R-SCE-76066|rcsb pdb:6EU1|dip:DIP-887N|mint:Q04307|sgd:YDR045C(identity)	refseq:XP_006723242.1|refseq:NP_037500.2|refseq:NP_976219.1|refseq:XP_005258889.1|ensembl:ENSG00000167565(gene)|ensembl:ENST00000322354(transcript)|ensembl:ENST00000392028(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR009263(SERTA)|interpro:IPR039585|entrezgene/locuslink:29946(identity)	-	crc64:E4AA802EC9F92230	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:G2fIQbptabHIUI224iPtTJF+dIs559292	rogid:zraVKcqHA7SNRrMV50iyPK6O7ok9606	intact-crc:0A6282333CB5B152|rigid:MzT3LybxicBeAZjMmgwBKUpdDGo	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9NNX1-2	uniprotkb:Q04307	intact:EBI-11535232|ensembl:ENSP00000357841	intact:EBI-15858|uniprotkb:Q2VQW5|ensemblfungi:YDR045C|uniprotkb:D6VS33	psi-mi:q9nnx1-2(display_long)|uniprotkb:TUFT1(gene name)|psi-mi:TUFT1(display_short)	psi-mi:rpc10_yeast(display_long)|uniprotkb:RPC11(gene name)|psi-mi:RPC11(display_short)|uniprotkb:YDR045C(locus name)|uniprotkb:YD9609.01C(orf name)|uniprotkb:RNA polymerase III subunit C11(gene name synonym)|uniprotkb:DNA-directed RNA polymerases III 12.5 kDa polypeptide(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11535230|imex:IM-24995-1351	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-2557363(isoform-parent)|ensembl:ENSG00000143367(gene)|ensembl:ENST00000368848(transcript)|uniprotkb:Q9NNX1-2(isoform-parent)|entrezgene/locuslink:7286(identity)	ensemblfungi:YDR045C(gene)|refseq:NP_010330.1|sgd:S000002452|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006386"(termination of RNA polymerase III transcription)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042779"(tRNA 3'-trailer cleavage)|go:"GO:0042797"(tRNA transcription by RNA polymerase III)|interpro:IPR001222(Zinc finger, TFIIS-type)|interpro:IPR001529(DNA-directed RNA polymerase, M/15 kDa subunit)|interpro:IPR012164(DNA-directed RNA polymerase, subunit C11/M/9)|interpro:IPR019761|interpro:IPR034014|rcsb pdb:3QT1|ensemblfungi:YDR045C_mRNA(transcript)|rcsb pdb:5FJ8|rcsb pdb:5FJ9|rcsb pdb:5FJA|rcsb pdb:6CNB|rcsb pdb:6CNC|rcsb pdb:6CND|rcsb pdb:6CNF|rcsb pdb:6EU0|rcsb pdb:6EU2|rcsb pdb:6EU3|rcsb pdb:6F40|rcsb pdb:6F41|rcsb pdb:6F42|rcsb pdb:6F44|rcsb pdb:6TUT|reactome:R-SCE-76061|reactome:R-SCE-76066|rcsb pdb:6EU1|dip:DIP-887N|mint:Q04307|sgd:YDR045C(identity)	-	-	crc64:E4AA802EC9F92230	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Xt8rl/ePRyc25U9+KY9b8o1IcNs9606	rogid:G2fIQbptabHIUI224iPtTJF+dIs559292	intact-crc:22ED024FAB71A3A2|rigid:LHE5xu/Xg2ztWFBt6i7YHI5S7XU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q04307	uniprotkb:Q93062-3	intact:EBI-15858|uniprotkb:Q2VQW5|ensemblfungi:YDR045C|uniprotkb:D6VS33	intact:EBI-740343|ensembl:ENSP00000340176	psi-mi:rpc10_yeast(display_long)|uniprotkb:RPC11(gene name)|psi-mi:RPC11(display_short)|uniprotkb:YDR045C(locus name)|uniprotkb:YD9609.01C(orf name)|uniprotkb:RNA polymerase III subunit C11(gene name synonym)|uniprotkb:DNA-directed RNA polymerases III 12.5 kDa polypeptide(gene name synonym)	psi-mi:q93062-3(display_long)|uniprotkb:RBPMS(gene name)|psi-mi:RBPMS(display_short)|uniprotkb:HERMES(gene name synonym)|uniprotkb:Heart and RRM expressed sequence(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11535221|imex:IM-24995-1350	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YDR045C(gene)|refseq:NP_010330.1|sgd:S000002452|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006386"(termination of RNA polymerase III transcription)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042779"(tRNA 3'-trailer cleavage)|go:"GO:0042797"(tRNA transcription by RNA polymerase III)|interpro:IPR001222(Zinc finger, TFIIS-type)|interpro:IPR001529(DNA-directed RNA polymerase, M/15 kDa subunit)|interpro:IPR012164(DNA-directed RNA polymerase, subunit C11/M/9)|interpro:IPR019761|interpro:IPR034014|rcsb pdb:3QT1|ensemblfungi:YDR045C_mRNA(transcript)|rcsb pdb:5FJ8|rcsb pdb:5FJ9|rcsb pdb:5FJA|rcsb pdb:6CNB|rcsb pdb:6CNC|rcsb pdb:6CND|rcsb pdb:6CNF|rcsb pdb:6EU0|rcsb pdb:6EU2|rcsb pdb:6EU3|rcsb pdb:6F40|rcsb pdb:6F41|rcsb pdb:6F42|rcsb pdb:6F44|rcsb pdb:6TUT|reactome:R-SCE-76061|reactome:R-SCE-76066|rcsb pdb:6EU1|dip:DIP-887N|mint:Q04307|sgd:YDR045C(identity)	intact:EBI-740322(rbpms_human)|uniprotkb:Q93062-3(isoform-parent)|ensembl:ENSG00000157110(gene)|ensembl:ENST00000339877(transcript)|entrezgene/locuslink:11030(identity)	-	crc64:E4AA802EC9F92230	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:G2fIQbptabHIUI224iPtTJF+dIs559292	rogid:nlPMQAJoKEbPYBwsL3xodmCKd7c9606	intact-crc:54CDDF269A0072FF|rigid:ivhDb+JqObLZCtlrAtGVpM86ook	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8TAP6	uniprotkb:Q04307	intact:EBI-742887|ensembl:ENSP00000262127|uniprotkb:Q658N5|uniprotkb:Q9H9U7|uniprotkb:B0YJB2|uniprotkb:B4DXG5|uniprotkb:B4DZW1	intact:EBI-15858|uniprotkb:Q2VQW5|ensemblfungi:YDR045C|uniprotkb:D6VS33	psi-mi:cep76_human(display_long)|uniprotkb:CEP76(gene name)|psi-mi:CEP76(display_short)|uniprotkb:C18orf9(gene name synonym)	psi-mi:rpc10_yeast(display_long)|uniprotkb:RPC11(gene name)|psi-mi:RPC11(display_short)|uniprotkb:YDR045C(locus name)|uniprotkb:YD9609.01C(orf name)|uniprotkb:RNA polymerase III subunit C11(gene name synonym)|uniprotkb:DNA-directed RNA polymerases III 12.5 kDa polypeptide(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11535212|imex:IM-24995-1349	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_079175.2|ensembl:ENSG00000101624(gene)|ensembl:ENST00000262127(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0046599"(regulation of centriole replication)|interpro:IPR028926|interpro:IPR038765|mint:Q8TAP6|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_001258918.1|entrezgene/locuslink:79959(identity)	ensemblfungi:YDR045C(gene)|refseq:NP_010330.1|sgd:S000002452|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006386"(termination of RNA polymerase III transcription)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042779"(tRNA 3'-trailer cleavage)|go:"GO:0042797"(tRNA transcription by RNA polymerase III)|interpro:IPR001222(Zinc finger, TFIIS-type)|interpro:IPR001529(DNA-directed RNA polymerase, M/15 kDa subunit)|interpro:IPR012164(DNA-directed RNA polymerase, subunit C11/M/9)|interpro:IPR019761|interpro:IPR034014|rcsb pdb:3QT1|ensemblfungi:YDR045C_mRNA(transcript)|rcsb pdb:5FJ8|rcsb pdb:5FJ9|rcsb pdb:5FJA|rcsb pdb:6CNB|rcsb pdb:6CNC|rcsb pdb:6CND|rcsb pdb:6CNF|rcsb pdb:6EU0|rcsb pdb:6EU2|rcsb pdb:6EU3|rcsb pdb:6F40|rcsb pdb:6F41|rcsb pdb:6F42|rcsb pdb:6F44|rcsb pdb:6TUT|reactome:R-SCE-76061|reactome:R-SCE-76066|rcsb pdb:6EU1|dip:DIP-887N|mint:Q04307|sgd:YDR045C(identity)	-	-	crc64:E4AA802EC9F92230	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:fWzb8oIU35oVWomyDrf8u5sbxUk9606	rogid:G2fIQbptabHIUI224iPtTJF+dIs559292	intact-crc:E5CBF8F5713E6F58|rigid:weMc+1uTiK5j8BMXnQgGYI5a/DA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O95273	uniprotkb:Q04712	intact:EBI-748961|uniprotkb:A8K3Q0|uniprotkb:A8K3U2|uniprotkb:Q6ZQN9|uniprotkb:Q7Z519|uniprotkb:Q8NBS7|uniprotkb:Q8NBY2|uniprotkb:Q9NS19|uniprotkb:Q9NYH3|uniprotkb:Q9UHX9|ensembl:ENSP00000300213	intact:EBI-27790|uniprotkb:D6VZD2|ensemblfungi:YML043C	psi-mi:ccdb1_human(display_long)|uniprotkb:Grap2 and cyclin-D-interacting protein(gene name synonym)|uniprotkb:Human homolog of Maid(gene name synonym)|uniprotkb:CCNDBP1(gene name)|psi-mi:CCNDBP1(display_short)|uniprotkb:DIP1(gene name synonym)|uniprotkb:GCIP(gene name synonym)|uniprotkb:HHM(gene name synonym)	psi-mi:rrn11_yeast(display_long)|uniprotkb:YM9827.09C(orf name)|uniprotkb:YML043C(locus name)|uniprotkb:RRN11(gene name)|psi-mi:RRN11(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11535296|imex:IM-24995-1357	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_036274.3|ensembl:ENSG00000166946(gene)|ensembl:ENST00000300213(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0016604"(nuclear body)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR026907|mint:O95273|rcsb pdb:3AY5|entrezgene/locuslink:23582(identity)	refseq:NP_013669.1|sgd:S000004507|dip:DIP-4542N|mint:Q04712|ensemblfungi:YML043C(gene)|ensemblfungi:YML043C_mRNA(transcript)|go:"GO:0001164"(RNA polymerase I core promoter sequence-specific DNA binding)|go:"GO:0001181"(RNA polymerase I general transcription initiation factor activity)|go:"GO:0005730"(nucleolus)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0042790"(nucleolar large rRNA transcription by RNA polymerase I)|go:"GO:0070860"(RNA polymerase I core factor complex)|interpro:IPR007224(RNA polymerase I specific initiation factor)|interpro:IPR016850(Core factor complex, Rrn11 component)|rcsb pdb:5N5Y|rcsb pdb:5N5Z|rcsb pdb:5N60|rcsb pdb:5N61|rcsb pdb:5O7X|rcsb pdb:5OA1|rcsb pdb:5W5Y|rcsb pdb:5W64|rcsb pdb:5W65|rcsb pdb:5W66|rcsb pdb:6RQH|rcsb pdb:6RQL|rcsb pdb:6RRD|rcsb pdb:6RUI|rcsb pdb:6RUO|rcsb pdb:6RWE|rcsb pdb:6TPS|sgd:YML043C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Vi9aoFc+Mov6P3X6KGmsTxXqxvM9606	rogid:HeXVovHQGBfbg6FbSkFO9/T64hE559292	intact-crc:9D0BBE217B115B6F|rigid:kDcumX4pkJwS3XoIcxA5QZJa6JE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q04638	uniprotkb:Q8N5R6	intact:EBI-27858|uniprotkb:D6VZA5|ensemblfungi:YML068W	intact:EBI-740841|intact:EBI-953781|uniprotkb:B3KQ49|uniprotkb:A8K3U4|uniprotkb:A8MPQ6|uniprotkb:A8MV61|uniprotkb:A8MVU9|uniprotkb:Q9H5Q6|uniprotkb:Q8TAX6|intact:EBI-2320546|intact:EBI-11522976	psi-mi:itt1_yeast(display_long)|uniprotkb:ITT1(gene name)|psi-mi:ITT1(display_short)|uniprotkb:YML068W(locus name)	psi-mi:ccd33_human(display_long)|uniprotkb:CCDC33(gene name)|psi-mi:CCDC33(display_short)|uniprotkb:Cancer/testis antigen 61(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11535287|imex:IM-24995-1356	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013643.1|sgd:S000004533|dip:DIP-1952N|mint:Q04638|ensemblfungi:YML068W(gene)|ensemblfungi:YML068W_mRNA(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005737"(cytoplasm)|go:"GO:0006449"(regulation of translational termination)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002867(Zinc finger, C6HC-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR031127|interpro:IPR044066|sgd:YML068W(identity)	refseq:NP_079331.3|interpro:IPR000008(C2 calcium-dependent membrane targeting)|go:"GO:0005777"(peroxisome)|refseq:NP_001274110.1|refseq:NP_877592.2|mint:Q8N5R6|interpro:IPR035892|interpro:IPR039889|entrezgene/locuslink:80125(identity)	-	crc64:F481372B742AF63D	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2021/11/30	rogid:gPNBZ7jeo4QD4M26MqrTGBZqVZY559292	rogid:eEIn7pQyfdHWx8TeLJpYy0i/gww9606	intact-crc:580FD68AA04FE11B|rigid:Rv1qP9yRgGM74WMA2bnWZQ0Rev4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q04603	uniprotkb:Q01658	intact:EBI-29938|uniprotkb:D6VSA7|ensemblfungi:YDR121W	intact:EBI-750300|ensembl:ENSP00000359290|ensembl:ENSP00000359295	psi-mi:dpb4_yeast(display_long)|uniprotkb:DPB4(gene name)|psi-mi:DPB4(display_short)|uniprotkb:DNA polymerase II subunit D(gene name synonym)|uniprotkb:YDR121W(locus name)	psi-mi:nc2b_human(display_long)|uniprotkb:Down-regulator of transcription 1(gene name synonym)|uniprotkb:TATA-binding protein-associated phosphoprotein(gene name synonym)|uniprotkb:Negative cofactor 2-beta(gene name synonym)|uniprotkb:DR1(gene name)|psi-mi:DR1(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11535278|imex:IM-24995-1355	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002528|refseq:NP_010406.3|dip:DIP-4621N|mint:Q04603|ensemblfungi:YDR121W(gene)|ensemblfungi:YDR121W_mRNA(transcript)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006272"(leading strand elongation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008622"(epsilon DNA polymerase complex)|go:"GO:0008623"(CHRAC)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0042276"(error-prone translesion synthesis)|go:"GO:0042766"(nucleosome mobilization)|go:"GO:0043044"|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0070868"(obsolete heterochromatin organization involved in chromatin silencing)|go:"GO:0090305"(nucleic acid phosphodiester bond hydrolysis)|interpro:IPR009072(Histone-fold)|rcsb pdb:6WJV|reactome:R-SCE-5656169|reactome:R-SCE-6782135|reactome:R-SCE-68952|reactome:R-SCE-68962|sgd:YDR121W(identity)	refseq:NP_001929.1|ensembl:ENSG00000117505(gene)|ensembl:ENST00000370267(transcript)|ensembl:ENST00000370272(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0017054"(negative cofactor 2 complex)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR003958(Transcription factor CBF/NF-Y/archaeal histone)|interpro:IPR009072(Histone-fold)|interpro:IPR042225|mint:Q01658|rcsb pdb:1JFI|reactome:R-HSA-3214847|entrezgene/locuslink:1810(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:vEA21+6hLP2O4eSSuKA49lbi0E0559292	rogid:lrcYCVWbIkFU01ETSmd3cX++jLw9606	intact-crc:7CDC212E23A66F41|rigid:0oW2EWGQH4fLj7PWG+Nqd7E+B4U	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8N9N5-2	uniprotkb:Q04599	intact:EBI-11524452|ensembl:ENSP00000347125	intact:EBI-38719|uniprotkb:D6VSA1|ensemblfungi:YDR116C	psi-mi:q8n9n5-2(display_long)|uniprotkb:BANP(gene name)|psi-mi:BANP(display_short)|uniprotkb:BEN domain-containing protein 1(gene name synonym)|uniprotkb:BEND1(gene name synonym)|uniprotkb:Btg3-associated nuclear protein(gene name synonym)|uniprotkb:SMAR1(gene name synonym)|uniprotkb:Scaffold/matrix-associated region-1-binding protein(gene name synonym)	psi-mi:rm01_yeast(display_long)|uniprotkb:MRPL1(gene name)|psi-mi:MRPL1(display_short)|uniprotkb:Mitochondrial large ribosomal subunit protein uL1m(gene name synonym)|uniprotkb:YD9727.11C(orf name)|uniprotkb:YDR116C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11535269|imex:IM-24995-1354	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000172530(gene)|ensembl:ENST00000355022(transcript)|intact:EBI-744695(isoform-parent)|uniprotkb:Q8N9N5-2(isoform-parent)|entrezgene/locuslink:54971(identity)	refseq:NP_010401.1|sgd:S000002523|mint:Q04599|dip:DIP-5223N|ensemblfungi:YDR116C(gene)|ensemblfungi:YDR116C_mRNA(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR002143(Ribosomal protein L1)|interpro:IPR005879(Ribosomal protein L1, mitochondrial)|interpro:IPR016095(Ribosomal protein L1, 3-layer alpha/beta-sandwich)|interpro:IPR023673|interpro:IPR023674|interpro:IPR028364|sgd:YDR116C(identity)	-	-	crc64:59DB6C5D10421A77	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:ESe6iCAhvq+i57fQHz3rGyg6UOo9606	rogid:Vco7wlmhTOETdBwIRgrjIdRR92w559292	intact-crc:57738B597C606DD6|rigid:p1xQkU70QRwfT53XY1ZT+tRdRTc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:A2A369	uniprotkb:Q04461	intact:EBI-11530808|ensembl:ENSP00000371766	intact:EBI-27209|uniprotkb:D6VZT4|ensemblfungi:YMR111C	psi-mi:a2a369_human(display_long)|uniprotkb:DOCK8(gene name)|psi-mi:DOCK8(display_short)	psi-mi:euc1_yeast(display_long)|uniprotkb:EUC1(gene name)|psi-mi:EUC1(display_short)|uniprotkb:Enriches ubiquitin on chromatin protein 1(gene name synonym)|uniprotkb:YM9718.10C(orf name)|uniprotkb:YMR111C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11535258|imex:IM-24995-1353	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000107099(gene)|ensembl:ENST00000382329(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0007264"(small GTPase mediated signal transduction)|interpro:IPR010703(Dedicator of cytokinesis)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026791|interpro:IPR027007|interpro:IPR027357|interpro:IPR035892|interpro:IPR043161|interpro:IPR043162|entrezgene/locuslink:81704(identity)	refseq:NP_013829.1|sgd:S000004717|dip:DIP-2716N|ensemblfungi:YMR111C(gene)|ensemblfungi:YMR111C_mRNA(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0034629"|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0060963"(positive regulation of ribosomal protein gene transcription by RNA polymerase II)|interpro:IPR022210|sgd:YMR111C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Sa5ulmmVxrpxZ+GAhN64RAHXYdk9606	rogid:Wpg0ztvlnbV6BXPwJKqWehavPGA559292	intact-crc:5153F7BE55147EF3|rigid:BpcaaJVBWTylkwcmkR9N9YwL7EQ	false	sufficient binding region:1054-1566	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q04712	uniprotkb:Q9Y6K9	intact:EBI-27790|uniprotkb:D6VZD2|ensemblfungi:YML043C	intact:EBI-81279|intact:EBI-356130|uniprotkb:Q7LBY6|uniprotkb:Q7Z7F1|ensembl:ENSP00000471166|ensembl:ENSP00000479662	psi-mi:rrn11_yeast(display_long)|uniprotkb:YM9827.09C(orf name)|uniprotkb:YML043C(locus name)|uniprotkb:RRN11(gene name)|psi-mi:RRN11(display_short)	psi-mi:nemo_human(display_long)|uniprotkb:IKBKG(gene name)|psi-mi:IKBKG(display_short)|uniprotkb:FIP3(gene name synonym)|uniprotkb:NEMO(gene name synonym)|uniprotkb:NF-kappa-B essential modifier(gene name synonym)|uniprotkb:Inhibitor of nuclear factor kappa-B kinase subunit gamma(gene name synonym)|uniprotkb:IkB kinase-associated protein 1(gene name synonym)|uniprotkb:FIP-3(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11535332|imex:IM-24995-1361	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013669.1|sgd:S000004507|dip:DIP-4542N|mint:Q04712|ensemblfungi:YML043C(gene)|ensemblfungi:YML043C_mRNA(transcript)|go:"GO:0001164"(RNA polymerase I core promoter sequence-specific DNA binding)|go:"GO:0001181"(RNA polymerase I general transcription initiation factor activity)|go:"GO:0005730"(nucleolus)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0042790"(nucleolar large rRNA transcription by RNA polymerase I)|go:"GO:0070860"(RNA polymerase I core factor complex)|interpro:IPR007224(RNA polymerase I specific initiation factor)|interpro:IPR016850(Core factor complex, Rrn11 component)|rcsb pdb:5N5Y|rcsb pdb:5N5Z|rcsb pdb:5N60|rcsb pdb:5N61|rcsb pdb:5O7X|rcsb pdb:5OA1|rcsb pdb:5W5Y|rcsb pdb:5W64|rcsb pdb:5W65|rcsb pdb:5W66|rcsb pdb:6RQH|rcsb pdb:6RQL|rcsb pdb:6RRD|rcsb pdb:6RUI|rcsb pdb:6RUO|rcsb pdb:6RWE|rcsb pdb:6TPS|sgd:YML043C(identity)	refseq:NP_001308325.1|refseq:NP_001308326.1|refseq:NP_001093326.2|refseq:NP_001093327.1|refseq:NP_001138727.1|refseq:NP_003630.1|dip:DIP-27528N|ensembl:ENSG00000269335(gene)|ensembl:ENST00000594239(transcript)|ensembl:ENST00000611071(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0008385"(IkappaB kinase complex)|go:"GO:0009615"(response to virus)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043276"(anoikis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050862"(positive regulation of T cell receptor signaling pathway)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051650"(establishment of vesicle localization)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1990450"(linear polyubiquitin binding)|go:"GO:1990459"(transferrin receptor binding)|interpro:IPR021063|interpro:IPR032419|interpro:IPR034735|mint:Q9Y6K9|rcsb pdb:2JVX|rcsb pdb:2JVY|rcsb pdb:3BRT|rcsb pdb:3BRV|rcsb pdb:3CL3|rcsb pdb:3FX0|rcsb pdb:4BWN|rcsb pdb:5AAY|rcsb pdb:5LDE|rcsb pdb:6MI3|rcsb pdb:6MI4|rcsb pdb:6YEK|reactome:R-HSA-1169091|reactome:R-HSA-1236974|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-1810476|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-4755510|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5602636|reactome:R-HSA-5603027|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5684264|reactome:R-HSA-5689880|reactome:R-HSA-5689896|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-933543|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-975144|entrezgene/locuslink:8517(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:HeXVovHQGBfbg6FbSkFO9/T64hE559292	rogid:9OeZIMeJvNtDEMoiLaKwVEpxSSM9606	intact-crc:1C4E424A1F8B6790|rigid:Yb0h9SnRLz93S+simkWtrCpcYQg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9Y2D8	uniprotkb:Q04712	intact:EBI-2212028|uniprotkb:B4DFE3|uniprotkb:J3KR02|uniprotkb:A8K8W0|uniprotkb:D3DT13|uniprotkb:Q6P2P8|uniprotkb:Q6ULS1|uniprotkb:Q7L168|uniprotkb:Q9UIX0|intact:EBI-10964529|ensembl:ENSP00000340279	intact:EBI-27790|uniprotkb:D6VZD2|ensemblfungi:YML043C	psi-mi:adip_human(display_long)|uniprotkb:SSX2IP(gene name)|psi-mi:SSX2IP(display_short)|uniprotkb:KIAA0923(gene name synonym)|uniprotkb:Afadin DIL domain-interacting protein(gene name synonym)|uniprotkb:SSX2-interacting protein(gene name synonym)	psi-mi:rrn11_yeast(display_long)|uniprotkb:YM9827.09C(orf name)|uniprotkb:YML043C(locus name)|uniprotkb:RRN11(gene name)|psi-mi:RRN11(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11535323|imex:IM-24995-1360	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011538912.1|refseq:NP_001159765.1|refseq:NP_001159766.1|refseq:NP_001159767.1|refseq:NP_001159889.1|refseq:NP_054740.3|refseq:XP_005270484.1|refseq:XP_005270485.1|refseq:XP_006710394.1|refseq:XP_016855723.1|ensembl:ENSG00000117155(gene)|ensembl:ENST00000342203(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005912"(adherens junction)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031252"(cell leading edge)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0035735"(intraciliary transport involved in cilium assembly)|go:"GO:0036064"(ciliary basal body)|go:"GO:0060271"(cilium assembly)|go:"GO:2000145"(regulation of cell motility)|interpro:IPR021622|mint:Q9Y2D8|entrezgene/locuslink:117178(identity)	refseq:NP_013669.1|sgd:S000004507|dip:DIP-4542N|mint:Q04712|ensemblfungi:YML043C(gene)|ensemblfungi:YML043C_mRNA(transcript)|go:"GO:0001164"(RNA polymerase I core promoter sequence-specific DNA binding)|go:"GO:0001181"(RNA polymerase I general transcription initiation factor activity)|go:"GO:0005730"(nucleolus)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0042790"(nucleolar large rRNA transcription by RNA polymerase I)|go:"GO:0070860"(RNA polymerase I core factor complex)|interpro:IPR007224(RNA polymerase I specific initiation factor)|interpro:IPR016850(Core factor complex, Rrn11 component)|rcsb pdb:5N5Y|rcsb pdb:5N5Z|rcsb pdb:5N60|rcsb pdb:5N61|rcsb pdb:5O7X|rcsb pdb:5OA1|rcsb pdb:5W5Y|rcsb pdb:5W64|rcsb pdb:5W65|rcsb pdb:5W66|rcsb pdb:6RQH|rcsb pdb:6RQL|rcsb pdb:6RRD|rcsb pdb:6RUI|rcsb pdb:6RUO|rcsb pdb:6RWE|rcsb pdb:6TPS|sgd:YML043C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:E0VeMRF9SrpQKSJFP01XEbMjeF89606	rogid:HeXVovHQGBfbg6FbSkFO9/T64hE559292	intact-crc:C1CFD1A89A8781FA|rigid:b6xKGsfdNTImjel1uUuhs1+q4Gs	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q04712	uniprotkb:Q9UPY8	intact:EBI-27790|uniprotkb:D6VZD2|ensemblfungi:YML043C	intact:EBI-726739|uniprotkb:O00265|uniprotkb:Q6FI15|uniprotkb:Q9BZP7|uniprotkb:Q9BZP8|uniprotkb:B7WPK5|uniprotkb:Q6FHB0|ensembl:ENSP00000233121	psi-mi:rrn11_yeast(display_long)|uniprotkb:YM9827.09C(orf name)|uniprotkb:YML043C(locus name)|uniprotkb:RRN11(gene name)|psi-mi:RRN11(display_short)	psi-mi:mare3_human(display_long)|uniprotkb:End-binding protein 3(gene name synonym)|uniprotkb:EB1 protein family member 3(gene name synonym)|uniprotkb:RP3(gene name synonym)|uniprotkb:MAPRE3(gene name)|psi-mi:MAPRE3(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11535314|imex:IM-24995-1359	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013669.1|sgd:S000004507|dip:DIP-4542N|mint:Q04712|ensemblfungi:YML043C(gene)|ensemblfungi:YML043C_mRNA(transcript)|go:"GO:0001164"(RNA polymerase I core promoter sequence-specific DNA binding)|go:"GO:0001181"(RNA polymerase I general transcription initiation factor activity)|go:"GO:0005730"(nucleolus)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0042790"(nucleolar large rRNA transcription by RNA polymerase I)|go:"GO:0070860"(RNA polymerase I core factor complex)|interpro:IPR007224(RNA polymerase I specific initiation factor)|interpro:IPR016850(Core factor complex, Rrn11 component)|rcsb pdb:5N5Y|rcsb pdb:5N5Z|rcsb pdb:5N60|rcsb pdb:5N61|rcsb pdb:5O7X|rcsb pdb:5OA1|rcsb pdb:5W5Y|rcsb pdb:5W64|rcsb pdb:5W65|rcsb pdb:5W66|rcsb pdb:6RQH|rcsb pdb:6RQL|rcsb pdb:6RRD|rcsb pdb:6RUI|rcsb pdb:6RUO|rcsb pdb:6RWE|rcsb pdb:6TPS|sgd:YML043C(identity)	refseq:NP_036458.2|refseq:XP_016859086.1|refseq:NP_001289979.1|refseq:XP_006712030.1|refseq:XP_011531002.1|dip:DIP-56069N|ensembl:ENSG00000084764(gene)|ensembl:ENST00000233121(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0008017"(microtubule binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030496"(midbody)|go:"GO:0031110"(regulation of microtubule polymerization or depolymerization)|go:"GO:0031113"(regulation of microtubule polymerization)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0042802"(identical protein binding)|go:"GO:0045737"(positive regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051233"(spindle midzone)|go:"GO:0051301"(cell division)|go:"GO:1903033"(positive regulation of microtubule plus-end binding)|go:"GO:1904825"(protein localization to microtubule plus-end)|go:"GO:1905721"(mitotic spindle astral microtubule end)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR004953(EB1, C-terminal)|interpro:IPR027328|interpro:IPR027738|interpro:IPR036133|interpro:IPR036872|mint:Q9UPY8|rcsb pdb:1WYO|rcsb pdb:3CO1|rcsb pdb:3JAK|rcsb pdb:3JAL|rcsb pdb:3JAR|rcsb pdb:3TQ7|entrezgene/locuslink:22924(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:HeXVovHQGBfbg6FbSkFO9/T64hE559292	rogid:LHuufxyNrygS3iFW5mmg13R43NE9606	intact-crc:F4B7A0F9AC4C1610|rigid:EFNPljGHdNbt+95Zb2JFXjKST4A	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q04712	uniprotkb:Q96MT8-3	intact:EBI-27790|uniprotkb:D6VZD2|ensemblfungi:YML043C	intact:EBI-11522539|ensembl:ENSP00000507703|ensembl:ENSP00000328382|ensembl:ENSP00000506728|ensembl:ENSP00000506791|ensembl:ENSP00000506828|ensembl:ENSP00000507228	psi-mi:rrn11_yeast(display_long)|uniprotkb:YM9827.09C(orf name)|uniprotkb:YML043C(locus name)|uniprotkb:RRN11(gene name)|psi-mi:RRN11(display_short)	psi-mi:q96mt8-3(display_long)|uniprotkb:CEP63(gene name)|psi-mi:CEP63(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11535305|imex:IM-24995-1358	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013669.1|sgd:S000004507|dip:DIP-4542N|mint:Q04712|ensemblfungi:YML043C(gene)|ensemblfungi:YML043C_mRNA(transcript)|go:"GO:0001164"(RNA polymerase I core promoter sequence-specific DNA binding)|go:"GO:0001181"(RNA polymerase I general transcription initiation factor activity)|go:"GO:0005730"(nucleolus)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0042790"(nucleolar large rRNA transcription by RNA polymerase I)|go:"GO:0070860"(RNA polymerase I core factor complex)|interpro:IPR007224(RNA polymerase I specific initiation factor)|interpro:IPR016850(Core factor complex, Rrn11 component)|rcsb pdb:5N5Y|rcsb pdb:5N5Z|rcsb pdb:5N60|rcsb pdb:5N61|rcsb pdb:5O7X|rcsb pdb:5OA1|rcsb pdb:5W5Y|rcsb pdb:5W64|rcsb pdb:5W65|rcsb pdb:5W66|rcsb pdb:6RQH|rcsb pdb:6RQL|rcsb pdb:6RRD|rcsb pdb:6RUI|rcsb pdb:6RUO|rcsb pdb:6RWE|rcsb pdb:6TPS|sgd:YML043C(identity)	intact:EBI-741977(isoform-parent)|ensembl:ENST00000332047(transcript)|ensembl:ENST00000682042(transcript)|ensembl:ENST00000682800(transcript)|ensembl:ENST00000682858(transcript)|ensembl:ENST00000683177(transcript)|ensembl:ENST00000683861(transcript)|ensembl:ENSG00000182923(gene)|uniprotkb:Q96MT8-3(isoform-parent)|entrezgene/locuslink:80254(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:HeXVovHQGBfbg6FbSkFO9/T64hE559292	rogid:U0uvVcOCzA8Qp2cCB0ilixgd4Yc9606	intact-crc:2F24E0CBA66126BD|rigid:AF4Ija845Zk96YrfkC9lGqse1sk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q04978	uniprotkb:Q8TAP6	intact:EBI-27823|uniprotkb:D6VZC2|ensemblfungi:YML053C	intact:EBI-742887|ensembl:ENSP00000262127|uniprotkb:Q658N5|uniprotkb:Q9H9U7|uniprotkb:B0YJB2|uniprotkb:B4DXG5|uniprotkb:B4DZW1	psi-mi:ymf3_yeast(display_long)|uniprotkb:YM9958.09C(orf name)|uniprotkb:YML053C(locus name)	psi-mi:cep76_human(display_long)|uniprotkb:CEP76(gene name)|psi-mi:CEP76(display_short)|uniprotkb:C18orf9(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11535369|imex:IM-24995-1365	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000004517|refseq:NP_013659.1|dip:DIP-1950N|ensemblfungi:YML053C(gene)|ensemblfungi:YML053C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|sgd:YML053C(identity)	refseq:NP_079175.2|ensembl:ENSG00000101624(gene)|ensembl:ENST00000262127(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0046599"(regulation of centriole replication)|interpro:IPR028926|interpro:IPR038765|mint:Q8TAP6|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_001258918.1|entrezgene/locuslink:79959(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:eYvLCLQP+e6HSEiAjDeWkJBUCTU559292	rogid:fWzb8oIU35oVWomyDrf8u5sbxUk9606	intact-crc:1091FE48A9BEF423|rigid:Q71mEizYAeqEhHQP4PwKyLKNgpc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q04978	uniprotkb:O60684	intact:EBI-27823|uniprotkb:D6VZC2|ensemblfungi:YML053C	intact:EBI-359923|uniprotkb:Q5VVU3|uniprotkb:B2RDC7|ensembl:ENSP00000362728|uniprotkb:D3DPP5	psi-mi:ymf3_yeast(display_long)|uniprotkb:YM9958.09C(orf name)|uniprotkb:YML053C(locus name)	psi-mi:ima7_human(display_long)|uniprotkb:KPNA6(gene name)|psi-mi:KPNA6(display_short)|uniprotkb:IPOA7(gene name synonym)|uniprotkb:Karyopherin subunit alpha-6(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11535360|imex:IM-24995-1364	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000004517|refseq:NP_013659.1|dip:DIP-1950N|ensemblfungi:YML053C(gene)|ensemblfungi:YML053C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|sgd:YML053C(identity)	refseq:NP_036448.1|ensembl:ENSG00000025800(gene)|ensembl:ENST00000373625(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0016020"(membrane)|go:"GO:0019079"(viral genome replication)|go:"GO:0030682"(mitigation of host defenses by symbiont)|go:"GO:0043657"(host cell)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060135"(maternal process involved in female pregnancy)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0075506"(entry of viral genome into host nucleus through nuclear pore complex via importin)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:1903902"(positive regulation of viral life cycle)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|mint:O60684|rcsb pdb:4UAD|dip:DIP-27609N|entrezgene/locuslink:23633(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:eYvLCLQP+e6HSEiAjDeWkJBUCTU559292	rogid:3NsSIcE6BHIqYlvfGRolUKD/5uc9606	intact-crc:60CB217A20F4B3A4|rigid:GpHakCsqlndyZ6pH+os8y4W+2WU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96BA8	uniprotkb:Q04969	intact:EBI-6942903|ensembl:ENSP00000481956|intact:MINT-268046|intact:MINT-8162577|uniprotkb:Q8N2D5|uniprotkb:Q96CP0	intact:EBI-27827|uniprotkb:D6VZB9|ensemblfungi:YML055W	psi-mi:cr3l1_human(display_long)|uniprotkb:CREB3L1(gene name)|psi-mi:CREB3L1(display_short)|uniprotkb:OASIS(gene name synonym)|uniprotkb:PSEC0238(orf name)|uniprotkb:Old astrocyte specifically-induced substance(gene name synonym)	psi-mi:spc2_yeast(display_long)|uniprotkb:YML055W(locus name)|uniprotkb:YM9958.07(orf name)|uniprotkb:SPC2(gene name)|psi-mi:SPC2(display_short)|uniprotkb:SPY1(gene name synonym)|uniprotkb:Microsomal signal peptidase subunit 2(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11535350|imex:IM-24995-1363	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157613(gene)|ensembl:ENST00000621158(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0070278"(extracellular matrix constituent secretion)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029805|mint:Q96BA8|reactome:R-HSA-8874211|refseq:NP_443086.1|entrezgene/locuslink:90993(identity)	refseq:NP_013657.1|sgd:S000004519|dip:DIP-4540N|mint:Q04969|ensemblfungi:YML055W(gene)|ensemblfungi:YML055W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005787"(signal peptidase complex)|go:"GO:0006465"(signal peptide processing)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045047"(protein targeting to ER)|go:"GO:0120236"(negative regulation of posttranslational protein targeting to membrane, translocation)|interpro:IPR009582(Microsomal signal peptidase 25 kDa subunit)|sgd:YML055W(identity)	-	comment:mint|function:"Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE"	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:sMWUFmBeBBCO+T0Y2CuB/un1lBg9606	rogid:ZXf9rPA3/ryPnDqI4JGp0VMNMe4559292	intact-crc:756C8C72940B0F56|rigid:4iUkH+SMctTR3eWg5hEqFhhupzc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q04969	uniprotkb:Q8N6L0	intact:EBI-27827|uniprotkb:D6VZB9|ensemblfungi:YML055W	intact:EBI-749265|uniprotkb:Q96MC3|ensembl:ENSP00000404220	psi-mi:spc2_yeast(display_long)|uniprotkb:YML055W(locus name)|uniprotkb:YM9958.07(orf name)|uniprotkb:SPC2(gene name)|psi-mi:SPC2(display_short)|uniprotkb:SPY1(gene name synonym)|uniprotkb:Microsomal signal peptidase subunit 2(gene name synonym)	psi-mi:kash5_human(display_long)|uniprotkb:KASH5(gene name)|psi-mi:KASH5(display_short)|uniprotkb:CCDC155(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 155(gene name synonym)|uniprotkb:KASH domain-containing protein 5(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11535341|imex:IM-24995-1362	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013657.1|sgd:S000004519|dip:DIP-4540N|mint:Q04969|ensemblfungi:YML055W(gene)|ensemblfungi:YML055W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005787"(signal peptidase complex)|go:"GO:0006465"(signal peptide processing)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045047"(protein targeting to ER)|go:"GO:0120236"(negative regulation of posttranslational protein targeting to membrane, translocation)|interpro:IPR009582(Microsomal signal peptidase 25 kDa subunit)|sgd:YML055W(identity)	refseq:NP_653289.3|ensembl:ENSG00000161609(gene)|ensembl:ENST00000447857(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034397"(telomere localization)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051225"(spindle assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0090172"(microtubule cytoskeleton organization involved in homologous chromosome segregation)|go:"GO:0090220"(chromosome localization to nuclear envelope involved in homologous chromosome segregation)|go:"GO:0090619"(meiotic spindle pole)|interpro:IPR011992(EF-Hand type)|interpro:IPR028168|interpro:IPR028170|interpro:IPR039508|mint:Q8N6L0|rcsb pdb:6R2I|rcsb pdb:6WMF|entrezgene/locuslink:147872(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:ZXf9rPA3/ryPnDqI4JGp0VMNMe4559292	rogid:Wl9L7AcvDHCZuKjYLn8QgGIbZTc9606	intact-crc:FDEEC3B34F64237E|rigid:400OZ0VEOZXtLA3t20J6oKxeQQQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96DZ9-2	uniprotkb:Q05515	intact:EBI-11522780|ensembl:ENSP00000352270|ensembl:ENSP00000497215	intact:EBI-38400|uniprotkb:D6VSX6|ensemblfungi:YDR346C	psi-mi:q96dz9-2(display_long)|uniprotkb:CMTM5(gene name)|psi-mi:CMTM5(display_short)|uniprotkb:CKLFSF5(gene name synonym)|uniprotkb:Chemokine-like factor superfamily member 5(gene name synonym)	psi-mi:svf1_yeast(display_long)|uniprotkb:SVF1(gene name)|psi-mi:SVF1(display_short)|uniprotkb:SGI1(gene name synonym)|uniprotkb:YDR346C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11535407|imex:IM-24995-1369	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000166091(gene)|ensembl:ENST00000359320(transcript)|ensembl:ENST00000649278(transcript)|intact:EBI-2548702(isoform-parent)|uniprotkb:Q96DZ9-2(isoform-parent)|entrezgene/locuslink:116173(identity)	sgd:S000002754|refseq:NP_010633.3|mint:Q05515|dip:DIP-5243N|ensemblfungi:YDR346C(gene)|ensemblfungi:YDR346C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0034599"(cellular response to oxidative stress)|interpro:IPR013931(Oxidative stress survival, Svf1-like)|interpro:IPR033394|sgd:YDR346C(identity)	-	-	crc64:926A28FE140F87A5	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:2TJ7rZKQNb5hH5gz9i+ujOEOIOg9606	rogid:K9DLW9y+JFX3NTUKWKHVb/YpPVg559292	intact-crc:D48ADD9D7023D6AD|rigid:cHfqz9yeOR0kWYXEyZ1Kfja6aYE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O43791	uniprotkb:Q05164	intact:EBI-743549|uniprotkb:Q53HJ1|uniprotkb:B2R6S3|uniprotkb:D3DTW7|ensembl:ENSP00000240327|ensembl:ENSP00000377001|ensembl:ENSP00000420908|ensembl:ENSP00000424119|ensembl:ENSP00000425905|ensembl:ENSP00000426986|ensembl:ENSP00000499562	intact:EBI-31733|uniprotkb:Q08294|uniprotkb:D6W1R6|ensemblfungi:YOL155C	psi-mi:spop_human(display_long)|uniprotkb:HIB homolog 1(gene name synonym)|uniprotkb:Roadkill homolog 1(gene name synonym)|uniprotkb:SPOP(gene name)|psi-mi:SPOP(display_short)	psi-mi:hpf1_yeast(display_long)|uniprotkb:HPF1(gene name)|psi-mi:HPF1(display_short)|uniprotkb:AOF1001(orf name)|uniprotkb:YOL155C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11535398|imex:IM-24995-1368	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001007227.1|refseq:NP_001007228.1|refseq:NP_001007229.1|refseq:NP_001007230.1|refseq:NP_001007231.1|refseq:NP_003554.1|refseq:XP_005257780.1|refseq:XP_005257781.1|ensembl:ENSG00000121067(gene)|ensembl:ENST00000347630(transcript)|ensembl:ENST00000393328(transcript)|ensembl:ENST00000503676(transcript)|ensembl:ENST00000504102(transcript)|ensembl:ENST00000509079(transcript)|ensembl:ENST00000514121(transcript)|ensembl:ENST00000665825(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0016607"(nuclear speck)|go:"GO:0030162"(regulation of proteolysis)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR034089|mint:O43791|rcsb pdb:2CR2|rcsb pdb:3HQH|rcsb pdb:3HQI|rcsb pdb:3HQL|rcsb pdb:3HQM|rcsb pdb:3HSV|rcsb pdb:3HTM|rcsb pdb:3HU6|rcsb pdb:3IVB|rcsb pdb:3IVQ|rcsb pdb:3IVV|rcsb pdb:4EOZ|rcsb pdb:4HS2|rcsb pdb:4J8Z|rcsb pdb:4O1V|rcsb pdb:6F8F|rcsb pdb:6F8G|rcsb pdb:6I41|rcsb pdb:6I5P|rcsb pdb:6I68|rcsb pdb:6I7A|rcsb pdb:7D3D|rcsb pdb:7LIN|rcsb pdb:7LIO|rcsb pdb:7LIP|rcsb pdb:7LIQ|reactome:R-HSA-5632684|go:"GO:0005634"(nucleus)|refseq:XP_016880693.1|dip:DIP-50517N|entrezgene/locuslink:8405(identity)	sgd:S000005515|refseq:NP_014487.1|interpro:IPR021031|mint:Q05164|ensemblfungi:YOL155C(gene)|ensemblfungi:YOL155C_mRNA(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0009277"(fungal-type cell wall)|go:"GO:0015926"(glucosidase activity)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0071944"(cell periphery)|reactome:R-SCE-983168|sgd:YOL155C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:PC9ofpvk14xwTnnqT590/YRnx/49606	rogid:6bUWFxCsumvuNKLLVzCUfBbL1hA559292	intact-crc:65B7763BDC61EC1D|rigid:LtppZUYycnOgqRhpbMJVkBufiRg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:G5E962	uniprotkb:Q05164	intact:EBI-11525615|ensembl:ENSP00000328177	intact:EBI-31733|uniprotkb:Q08294|uniprotkb:D6W1R6|ensemblfungi:YOL155C	psi-mi:g5e962_human(display_long)|uniprotkb:hCG_1644200(orf name)|uniprotkb:MAGEA11(gene name)|psi-mi:MAGEA11(display_short)	psi-mi:hpf1_yeast(display_long)|uniprotkb:HPF1(gene name)|psi-mi:HPF1(display_short)|uniprotkb:AOF1001(orf name)|uniprotkb:YOL155C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11535387|imex:IM-24995-1367	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001011544.1|ensembl:ENSG00000185247(gene)|ensembl:ENST00000333104(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016604"(nuclear body)|interpro:IPR002190(MAGE protein)|interpro:IPR021072|interpro:IPR030099|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|entrezgene/locuslink:4110(identity)	sgd:S000005515|refseq:NP_014487.1|interpro:IPR021031|mint:Q05164|ensemblfungi:YOL155C(gene)|ensemblfungi:YOL155C_mRNA(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0009277"(fungal-type cell wall)|go:"GO:0015926"(glucosidase activity)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0071944"(cell periphery)|reactome:R-SCE-983168|sgd:YOL155C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:sVB0aA6yibWUx/d2SE+pwpKKgtI9606	rogid:6bUWFxCsumvuNKLLVzCUfBbL1hA559292	intact-crc:DCB2736A889BE711|rigid:MrtZO7x5n7XkNf1XvaUun1iGWrU	false	sufficient binding region:82-400	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q05021	uniprotkb:Q53G59	intact:EBI-27490|uniprotkb:D6W052|ensemblfungi:YMR227C	intact:EBI-740929|ensembl:ENSP00000356230|uniprotkb:A6NEN8|uniprotkb:B7Z7B8|uniprotkb:Q9HBX5	psi-mi:taf7_yeast(display_long)|uniprotkb:TAF7(gene name)|psi-mi:TAF7(display_short)|uniprotkb:TAF67(gene name synonym)|uniprotkb:YMR227C(locus name)|uniprotkb:YM9959.09C(orf name)|uniprotkb:TBP-associated factor 7(gene name synonym)|uniprotkb:TBP-associated factor 67 kDa(gene name synonym)|uniprotkb:TAFII-67(gene name synonym)	psi-mi:klh12_human(display_long)|uniprotkb:CUL3-interacting protein 1(gene name synonym)|uniprotkb:KLHL12(gene name)|psi-mi:KLHL12(display_short)|uniprotkb:C3IP1(gene name synonym)|uniprotkb:DKIR homolog(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11535378|imex:IM-24995-1366	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	mint:Q05021|refseq:NP_013954.1|sgd:S000004840|dip:DIP-6818N|ensemblfungi:YMR227C(gene)|ensemblfungi:YMR227C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|interpro:IPR006751(TAFII55 protein conserved region)|interpro:IPR037817|rcsb pdb:4OY2|reactome:R-SCE-674695|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-76042|sgd:YMR227C(identity)	go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048208"(COPII vesicle coating)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR017096(Kelch-like protein, gigaxonin)|mint:Q53G59|rcsb pdb:2VPJ|rcsb pdb:6TTK|rcsb pdb:6V7O|reactome:R-HSA-4641258|refseq:NP_067646.1|ensembl:ENSG00000117153(gene)|ensembl:ENST00000367261(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0014029"(neural crest formation)|go:"GO:0014032"(neural crest cell development)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0034451"(centriolar satellite)|refseq:NP_001289980.1|refseq:NP_001290038.1|entrezgene/locuslink:59349(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:VrnziwJxWKBtVBnyE3cijExq6/0559292	rogid:C4I/Ys9vqNqfG61HsXRZhywP4vE9606	intact-crc:FD2FAC4114FAA92D|rigid:cpfrkul7pqqF7qDfIyZG1amofRI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49760-3	uniprotkb:Q05947	intact:EBI-11535445|ensembl:ENSP00000354856|ensembl:ENSP00000459461	intact:EBI-33647|uniprotkb:D6VYM4|ensemblfungi:YLR224W	psi-mi:p49760-3(display_long)|uniprotkb:CDC-like kinase 2(gene name synonym)|uniprotkb:CLK2(gene name)|psi-mi:CLK2(display_short)	psi-mi:ucc1_yeast(display_long)|uniprotkb:UCC1(gene name)|psi-mi:UCC1(display_short)|uniprotkb:Ubiquitination of citrate synthase in the glyoxylate cycle protein 1(gene name synonym)|uniprotkb:YLR224W(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11535443|imex:IM-24995-1373	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-750020(isoform-parent)|ensembl:ENSG00000176444(gene)|ensembl:ENSG00000261893(gene)|ensembl:ENST00000361168(transcript)|ensembl:ENST00000572269(transcript)|uniprotkb:P49760-3(isoform-parent)|entrezgene/locuslink:1196(identity)	sgd:S000004214|refseq:NP_013325.1|mint:Q05947|dip:DIP-1630N|ensemblfungi:YLR224W(gene)|ensemblfungi:YLR224W_mRNA(transcript)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0071406"(cellular response to methylmercury)|sgd:YLR224W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:wFw4PjPFbFOw5k9Fqay3nAen8ZI9606	rogid:HOR8NxxNEa6zV2RmL1mMWrvNfEk559292	intact-crc:A6576A6B503F2FE9|rigid:dM41zON6cboSe/Qro4ldVJD1YVw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q05899	uniprotkb:Q99614	intact:EBI-33462|uniprotkb:D6VYU1|ensemblfungi:YLR297W	intact:EBI-742074|uniprotkb:Q9BVT3|uniprotkb:B2RCT2|uniprotkb:D3DQJ8|ensembl:ENSP00000231238|ensembl:ENSP00000429225|ensembl:ENSP00000507891	psi-mi:yl297_yeast(display_long)|uniprotkb:YLR297W(locus name)	psi-mi:ttc1_human(display_long)|uniprotkb:TTC1(gene name)|psi-mi:TTC1(display_short)|uniprotkb:TPR1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11535434|imex:IM-24995-1372	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000004288|refseq:NP_013400.1|dip:DIP-4684N|ensemblfungi:YLR297W(gene)|ensemblfungi:YLR297W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016021"(integral component of membrane)|sgd:YLR297W(identity)	refseq:NP_001269429.1|refseq:NP_003305.1|ensembl:ENST00000231238(transcript)|ensembl:ENST00000522793(transcript)|ensembl:ENST00000682719(transcript)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|ensembl:ENSG00000113312(gene)|entrezgene/locuslink:7265(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:5NnJTt1UJw0+xxbJS5roF36sLGI559292	rogid:jpDASWCrto0zMhBm3Cj9aDQURm09606	intact-crc:236859E7BFFDED36|rigid:EBQypxPb9QJrQeke+M9gnc/IFBo	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q05899	uniprotkb:O43765	intact:EBI-33462|uniprotkb:D6VYU1|ensemblfungi:YLR297W	intact:EBI-347996|ensembl:ENSP00000221566|ensembl:ENSP00000503397|ensembl:ENSP00000504495|uniprotkb:Q9BTZ9|intact:EBI-1045243|uniprotkb:Q6FIA9|uniprotkb:D6W610	psi-mi:yl297_yeast(display_long)|uniprotkb:YLR297W(locus name)	psi-mi:sgta_human(display_long)|uniprotkb:SGTA(gene name)|psi-mi:SGTA(display_short)|uniprotkb:SGT(gene name synonym)|uniprotkb:Alpha-SGT(gene name synonym)|uniprotkb:Vpu-binding protein(gene name synonym)|uniprotkb:SGT1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11535425|imex:IM-24995-1371	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000004288|refseq:NP_013400.1|dip:DIP-4684N|ensemblfungi:YLR297W(gene)|ensemblfungi:YLR297W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016021"(integral component of membrane)|sgd:YLR297W(identity)	rcsb pdb:4CPG|rcsb pdb:4GOD|rcsb pdb:4GOE|rcsb pdb:4GOF|reactome:R-HSA-9609523|rcsb pdb:2VYI|ensembl:ENSG00000104969(gene)|ensembl:ENST00000221566(transcript)|ensembl:ENST00000676943(transcript)|ensembl:ENST00000677149(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072380"(TRC complex)|go:"GO:0098850"(extrinsic component of synaptic vesicle membrane)|go:"GO:1903070"(negative regulation of ER-associated ubiquitin-dependent protein catabolic process)|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)|go:"GO:1903646"(positive regulation of chaperone-mediated protein folding)|go:"GO:1904288"(BAT3 complex binding)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR032374|mint:O43765|refseq:XP_011526480.1|refseq:NP_003012.1|entrezgene/locuslink:6449(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:5NnJTt1UJw0+xxbJS5roF36sLGI559292	rogid:r/Cyj4UJk/cS8QdrbjhTZMPCigI9606	intact-crc:091A9AD179470887|rigid:0yAmIuTTO1UefLVVsZaLO9S1Hs0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UI14	uniprotkb:Q05637	intact:EBI-712367|ensembl:ENSP00000222008|uniprotkb:Q7Z4Y2|uniprotkb:Q9Y3R1	intact:EBI-37326|uniprotkb:D6VSR1|ensemblfungi:YDR281C	psi-mi:praf1_human(display_long)|uniprotkb:PRA1 family protein 1(gene name synonym)|uniprotkb:RABAC1(gene name)|psi-mi:RABAC1(display_short)|uniprotkb:PRA1(gene name synonym)|uniprotkb:PRAF1(gene name synonym)	psi-mi:phm6_yeast(display_long)|uniprotkb:PHM6(gene name)|psi-mi:PHM6(display_short)|uniprotkb:D9954.14(orf name)|uniprotkb:YDR281C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11535416|imex:IM-24995-1370	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006414.2|ensembl:ENSG00000105404(gene)|ensembl:ENST00000222008(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0070064"(proline-rich region binding)|interpro:IPR004895(Prenylated rab acceptor PRA1)|mint:Q9UI14|entrezgene/locuslink:10567(identity)	sgd:S000002689|refseq:NP_010567.1|dip:DIP-4775N|ensemblfungi:YDR281C(gene)|ensemblfungi:YDR281C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0016021"(integral component of membrane)|sgd:YDR281C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:WS2rUY7yXRbR7pqWgfUCbnEiDbg9606	rogid:4CXswPUeUtOazQ3jQAWOO1E96Lg559292	intact-crc:5118AAE247BB7885|rigid:2WjLcCnzVfgd0x11TZ7gu507FkI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q06132	uniprotkb:P38432	intact:EBI-34377|uniprotkb:D6VYX6|ensemblfungi:YLR336C	intact:EBI-945751|uniprotkb:B2R931|ensembl:ENSP00000240316	psi-mi:sgd1_yeast(display_long)|uniprotkb:SGD1(gene name)|psi-mi:SGD1(display_short)|uniprotkb:YLR336C(locus name)	psi-mi:coil_human(display_long)|uniprotkb:COIL(gene name)|psi-mi:COIL(display_short)|uniprotkb:CLN80(gene name synonym)|uniprotkb:p80-coilin(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11535486|imex:IM-24995-1377	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013440.1|sgd:S000004328|mint:Q06132|dip:DIP-6333N|ensemblfungi:YLR336C(gene)|ensemblfungi:YLR336C_mRNA(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0006972"(hyperosmotic response)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0097078"(FAL1-SGD1 complex)|interpro:IPR003890(MIF4G-like, type 3)|interpro:IPR003891(Initiation factor eIF-4 gamma, MA3)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR016024(Armadillo-type fold)|sgd:YLR336C(identity)	refseq:NP_004636.1|dip:DIP-38503N|ensembl:ENSG00000121058(gene)|ensembl:ENST00000240316(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0015030"(Cajal body)|go:"GO:0016020"(membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0030619"(U1 snRNA binding)|go:"GO:0030620"(U2 snRNA binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR024822|interpro:IPR031722|mint:P38432|entrezgene/locuslink:8161(identity)	-	crc64:8EEFDB8258407FF3	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:FxZCxGejbcvEs/J2h1HEaWeVZLQ559292	rogid:hd5p6AbyA/GYNEeca99Mdb41qM09606	intact-crc:0DC2CB46C52F92B6|rigid:SO7As3jx3AzOgXxsft8fizVioPE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q6UN15	uniprotkb:Q06102	intact:EBI-1021914|uniprotkb:Q0VGE0|uniprotkb:Q499Y4|uniprotkb:Q49AU3|uniprotkb:Q7Z608|uniprotkb:Q8WVN3|uniprotkb:Q96F80|uniprotkb:Q9H077|intact:EBI-11535474|ensembl:ENSP00000336752|uniprotkb:B4DIR3|uniprotkb:G3XAD6	intact:EBI-38049|uniprotkb:D6W4A5|ensemblfungi:YPR107C	psi-mi:fip1_human(display_long)|uniprotkb:Factor interacting with PAP(gene name synonym)|uniprotkb:FIP1-like 1 protein(gene name synonym)|uniprotkb:Rearranged in hypereosinophilia(gene name synonym)|uniprotkb:FIP1L1(gene name)|psi-mi:FIP1L1(display_short)|uniprotkb:FIP1(gene name synonym)|uniprotkb:RHE(gene name synonym)	psi-mi:yth1_yeast(display_long)|uniprotkb:Yeast 30 kDa homolog 1(gene name synonym)|uniprotkb:YTH1(gene name)|psi-mi:YTH1(display_short)|uniprotkb:YPR107C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11535477|imex:IM-24995-1376	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000306932|ensembl:ENSP00000302993|ensembl:ENSP00000336752|ensembl:ENST00000358575|ensembl:ENSP00000351383|ensembl:ENST00000507922|ensembl:ENSP00000425456|refseq:NP_001128409.1|refseq:NP_001128410.1|refseq:NP_112179.2|ensembl:ENSG00000145216(gene)|ensembl:ENST00000337488(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|interpro:IPR007854(Fip1)|mint:Q6UN15|rcsb pdb:7K95|reactome:R-HSA-159231|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-77595|reactome:R-HSA-9673766|dip:DIP-42503N|entrezgene/locuslink:81608(identity)	refseq:NP_015432.1|sgd:S000006311|mint:Q06102|dip:DIP-2028N|ensemblfungi:YPR107C(gene)|ensemblfungi:YPR107C_mRNA(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR036855|rcsb pdb:6EOJ|reactome:R-SCE-77595|sgd:YPR107C(identity)	-	-	crc64:79C5993AE4E670EA	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/16	rogid:41uK1l8RV99q4k4Z7K9zeG3TJHA9606	rogid:rqNO3dAJtktR7RuM1ADpb9Nt0X8559292	intact-crc:6F2034BD8DBB52BE|rigid:fqElL4slW+Vuhpf1giO1nOAZ3po	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q06011	uniprotkb:Q8N9N5-2	intact:EBI-36392|uniprotkb:D6VZ25|ensemblfungi:YLR390W	intact:EBI-11524452|ensembl:ENSP00000347125	psi-mi:ecm19_yeast(display_long)|uniprotkb:ECM19(gene name)|psi-mi:ECM19(display_short)|uniprotkb:Extracellular mutant protein 19(gene name synonym)|uniprotkb:YLR390W(locus name)	psi-mi:q8n9n5-2(display_long)|uniprotkb:BANP(gene name)|psi-mi:BANP(display_short)|uniprotkb:BEN domain-containing protein 1(gene name synonym)|uniprotkb:BEND1(gene name synonym)|uniprotkb:Btg3-associated nuclear protein(gene name synonym)|uniprotkb:SMAR1(gene name synonym)|uniprotkb:Scaffold/matrix-associated region-1-binding protein(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11535465|imex:IM-24995-1375	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000004382|refseq:NP_013494.3|dip:DIP-8813N|ensemblfungi:YLR390W(gene)|ensemblfungi:YLR390W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0071555"(cell wall organization)|sgd:YLR390W(identity)	ensembl:ENSG00000172530(gene)|ensembl:ENST00000355022(transcript)|intact:EBI-744695(isoform-parent)|uniprotkb:Q8N9N5-2(isoform-parent)|entrezgene/locuslink:54971(identity)	-	crc64:B469042AC2025AA7	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:UBC9QbTkaTXXDvZdA/6/HJWDVqM559292	rogid:ESe6iCAhvq+i57fQHz3rGyg6UOo9606	intact-crc:46FFC274BEC94559|rigid:XAelBa76R8A2YR1Ckv+C/lnQi1I	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38432	uniprotkb:Q05955	intact:EBI-945751|uniprotkb:B2R931|ensembl:ENSP00000240316	intact:EBI-34541|uniprotkb:D6VYM7|ensemblfungi:YLR227C	psi-mi:coil_human(display_long)|uniprotkb:COIL(gene name)|psi-mi:COIL(display_short)|uniprotkb:CLN80(gene name synonym)|uniprotkb:p80-coilin(gene name synonym)	psi-mi:ady4_yeast(display_long)|uniprotkb:ADY4(gene name)|psi-mi:ADY4(display_short)|uniprotkb:L8083.11(orf name)|uniprotkb:YLR227C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11535456|imex:IM-24995-1374	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004636.1|dip:DIP-38503N|ensembl:ENSG00000121058(gene)|ensembl:ENST00000240316(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0015030"(Cajal body)|go:"GO:0016020"(membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0030619"(U1 snRNA binding)|go:"GO:0030620"(U2 snRNA binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR024822|interpro:IPR031722|mint:P38432|entrezgene/locuslink:8161(identity)	sgd:S000004217|refseq:NP_013328.1|dip:DIP-4786N|ensemblfungi:YLR227C(gene)|ensemblfungi:YLR227C_mRNA(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0030437"(ascospore formation)|go:"GO:0035974"(meiotic spindle pole body)|go:"GO:0051301"(cell division)|sgd:YLR227C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:hd5p6AbyA/GYNEeca99Mdb41qM09606	rogid:rYFhfauuzO793SGutv2Pee7hcBM559292	intact-crc:81E9DCD9533364BB|rigid:KMN+QdDdGOjToCWKTuBn3QggNs0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96BR9	uniprotkb:Q06132	intact:EBI-742740|uniprotkb:Q8IUL5|uniprotkb:Q8IWR9|uniprotkb:Q8N2Y5|uniprotkb:Q96BX0|ensembl:ENSP00000362609	intact:EBI-34377|uniprotkb:D6VYX6|ensemblfungi:YLR336C	psi-mi:zbt8a_human(display_long)|uniprotkb:ZBTB8A(gene name)|psi-mi:ZBTB8A(display_short)|uniprotkb:BOZF1(gene name synonym)|uniprotkb:BTB/POZ and zinc-finger domain-containing factor(gene name synonym)|uniprotkb:BTB/POZ and zinc-finger domains factor on chromosome 1(gene name synonym)	psi-mi:sgd1_yeast(display_long)|uniprotkb:SGD1(gene name)|psi-mi:SGD1(display_short)|uniprotkb:YLR336C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11535522|imex:IM-24995-1381	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000160062(gene)|ensembl:ENST00000373510(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|refseq:NP_001035531.2|refseq:NP_001278425.1|entrezgene/locuslink:653121(identity)	refseq:NP_013440.1|sgd:S000004328|mint:Q06132|dip:DIP-6333N|ensemblfungi:YLR336C(gene)|ensemblfungi:YLR336C_mRNA(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0006972"(hyperosmotic response)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0097078"(FAL1-SGD1 complex)|interpro:IPR003890(MIF4G-like, type 3)|interpro:IPR003891(Initiation factor eIF-4 gamma, MA3)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR016024(Armadillo-type fold)|sgd:YLR336C(identity)	-	-	crc64:8EEFDB8258407FF3	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:tsrPT2tHvuBryODKgRXnceXz9s09606	rogid:FxZCxGejbcvEs/J2h1HEaWeVZLQ559292	intact-crc:760B41DFE7BF60A7|rigid:OrBST+5s2tv+JURxyCkkkwDRIBs	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q06132	uniprotkb:Q8NHQ1	intact:EBI-34377|uniprotkb:D6VYX6|ensemblfungi:YLR336C	intact:EBI-739624|ensembl:ENSP00000264982|ensembl:ENSP00000419231|uniprotkb:Q96B31|uniprotkb:Q9H2C3|uniprotkb:Q9H2Z1|uniprotkb:Q9H940|uniprotkb:D3DNE9|uniprotkb:B7Z5I8|uniprotkb:B7Z7E8|uniprotkb:F5GZX8	psi-mi:sgd1_yeast(display_long)|uniprotkb:SGD1(gene name)|psi-mi:SGD1(display_short)|uniprotkb:YLR336C(locus name)	psi-mi:cep70_human(display_long)|uniprotkb:CEP70(gene name)|psi-mi:CEP70(display_short)|uniprotkb:BITE(gene name synonym)|uniprotkb:p10-binding protein(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11535513|imex:IM-24995-1380	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013440.1|sgd:S000004328|mint:Q06132|dip:DIP-6333N|ensemblfungi:YLR336C(gene)|ensemblfungi:YLR336C_mRNA(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0006972"(hyperosmotic response)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0097078"(FAL1-SGD1 complex)|interpro:IPR003890(MIF4G-like, type 3)|interpro:IPR003891(Initiation factor eIF-4 gamma, MA3)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR016024(Armadillo-type fold)|sgd:YLR336C(identity)	ensembl:ENSG00000114107(gene)|ensembl:ENST00000264982(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|interpro:IPR019734|interpro:IPR037692|mint:Q8NHQ1|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|ensembl:ENST00000484888(transcript)|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_077817.2|refseq:XP_016862764.1|refseq:NP_001275893.1|refseq:NP_001275894.1|refseq:NP_001275895.1|refseq:NP_001275896.1|refseq:NP_001307527.1|refseq:NP_001307529.1|entrezgene/locuslink:80321(identity)	-	crc64:8EEFDB8258407FF3	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:FxZCxGejbcvEs/J2h1HEaWeVZLQ559292	rogid:S4yveQWcvdVtAUX65gqrJ5Dv0Mc9606	intact-crc:B0A1724FEF2C49D0|rigid:PjjAmKyVVhJH+yc25AGY624IdxM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q06132	uniprotkb:Q53G59	intact:EBI-34377|uniprotkb:D6VYX6|ensemblfungi:YLR336C	intact:EBI-740929|ensembl:ENSP00000356230|uniprotkb:A6NEN8|uniprotkb:B7Z7B8|uniprotkb:Q9HBX5	psi-mi:sgd1_yeast(display_long)|uniprotkb:SGD1(gene name)|psi-mi:SGD1(display_short)|uniprotkb:YLR336C(locus name)	psi-mi:klh12_human(display_long)|uniprotkb:CUL3-interacting protein 1(gene name synonym)|uniprotkb:KLHL12(gene name)|psi-mi:KLHL12(display_short)|uniprotkb:C3IP1(gene name synonym)|uniprotkb:DKIR homolog(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11535504|imex:IM-24995-1379	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013440.1|sgd:S000004328|mint:Q06132|dip:DIP-6333N|ensemblfungi:YLR336C(gene)|ensemblfungi:YLR336C_mRNA(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0006972"(hyperosmotic response)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0097078"(FAL1-SGD1 complex)|interpro:IPR003890(MIF4G-like, type 3)|interpro:IPR003891(Initiation factor eIF-4 gamma, MA3)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR016024(Armadillo-type fold)|sgd:YLR336C(identity)	go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048208"(COPII vesicle coating)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR017096(Kelch-like protein, gigaxonin)|mint:Q53G59|rcsb pdb:2VPJ|rcsb pdb:6TTK|rcsb pdb:6V7O|reactome:R-HSA-4641258|refseq:NP_067646.1|ensembl:ENSG00000117153(gene)|ensembl:ENST00000367261(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0014029"(neural crest formation)|go:"GO:0014032"(neural crest cell development)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0034451"(centriolar satellite)|refseq:NP_001289980.1|refseq:NP_001290038.1|entrezgene/locuslink:59349(identity)	-	crc64:8EEFDB8258407FF3	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:FxZCxGejbcvEs/J2h1HEaWeVZLQ559292	rogid:C4I/Ys9vqNqfG61HsXRZhywP4vE9606	intact-crc:C9F00858D7586B44|rigid:uwuWNIj20Jz1K9Kbhna+kcAp4Ks	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P51116	uniprotkb:Q06132	intact:EBI-740459|uniprotkb:Q8WUM2|uniprotkb:Q86V09|uniprotkb:B2R9M2|uniprotkb:D3DTQ1|ensembl:ENSP00000250113	intact:EBI-34377|uniprotkb:D6VYX6|ensemblfungi:YLR336C	psi-mi:fxr2_human(display_long)|uniprotkb:FXR2(gene name)|psi-mi:FXR2(display_short)|uniprotkb:FMR1L2(gene name synonym)	psi-mi:sgd1_yeast(display_long)|uniprotkb:SGD1(gene name)|psi-mi:SGD1(display_short)|uniprotkb:YLR336C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11535495|imex:IM-24995-1378	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR004087(K Homology)|refseq:NP_004851.2|ensembl:ENSG00000129245(gene)|ensembl:ENST00000250113(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0044326"(dendritic spine neck)|go:"GO:0045182"(translation regulator activity)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0098793"(presynapse)|go:"GO:1902737"(dendritic filopodium)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|interpro:IPR004088(K Homology, type 1)|interpro:IPR008395(Agenet)|interpro:IPR022034|interpro:IPR032172|interpro:IPR036612|interpro:IPR040148|interpro:IPR040472|interpro:IPR041560|mint:P51116|rcsb pdb:3H8Z|entrezgene/locuslink:9513(identity)	refseq:NP_013440.1|sgd:S000004328|mint:Q06132|dip:DIP-6333N|ensemblfungi:YLR336C(gene)|ensemblfungi:YLR336C_mRNA(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0006972"(hyperosmotic response)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0097078"(FAL1-SGD1 complex)|interpro:IPR003890(MIF4G-like, type 3)|interpro:IPR003891(Initiation factor eIF-4 gamma, MA3)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR016024(Armadillo-type fold)|sgd:YLR336C(identity)	-	-	crc64:8EEFDB8258407FF3	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:NnYgyzD2NRGIO1ZHukr5qy44qRE9606	rogid:FxZCxGejbcvEs/J2h1HEaWeVZLQ559292	intact-crc:20BD3E66BFA2F914|rigid:xnbyTlAhgT+HBCSkbj2gfqWlCOw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8N6Y0	uniprotkb:Q06162	intact:EBI-739895|uniprotkb:Q8NBX7|uniprotkb:Q96KH3|uniprotkb:Q9BYI8|uniprotkb:A8K7L6|uniprotkb:B2RCR9|ensembl:ENSP00000252597	intact:EBI-34256|uniprotkb:D6VYV9|ensemblfungi:YLR315W	psi-mi:usbp1_human(display_long)|uniprotkb:USHBP1(gene name)|psi-mi:USHBP1(display_short)|uniprotkb:MCC-2(gene name synonym)|uniprotkb:AIE-75-binding protein(gene name synonym)|uniprotkb:AIEBP(gene name synonym)|uniprotkb:MCC2(gene name synonym)|uniprotkb:Mutated in colon cancer protein 2(gene name synonym)	psi-mi:nkp2_yeast(display_long)|uniprotkb:NKP2(gene name)|psi-mi:NKP2(display_short)|uniprotkb:Non-essential kinetochore protein 2(gene name synonym)|uniprotkb:YLR315W(locus name)|uniprotkb:Constitutive centromere-associated network protein NKP2(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11535551|imex:IM-24995-1384	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001284632.1|refseq:NP_114147.2|refseq:NP_001308346.1|ensembl:ENSG00000130307(gene)|ensembl:ENST00000252597(transcript)|go:"GO:0030165"(PDZ domain binding)|interpro:IPR019536|interpro:IPR040171|entrezgene/locuslink:83878(identity)	sgd:S000004307|refseq:NP_013419.1|mint:Q06162|dip:DIP-1939N|ensemblfungi:YLR315W(gene)|ensemblfungi:YLR315W_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0007059"(chromosome segregation)|go:"GO:0031511"(Mis6-Sim4 complex)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|interpro:IPR018565|rcsb pdb:6NUW|rcsb pdb:6QLD|rcsb pdb:6QLE|rcsb pdb:6QLF|sgd:YLR315W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:vY1qx73Ju/z7WDu6k1kd10ZDVRo9606	rogid:MT2+IEz8xQ2SVU5vvYYBI91cVKo559292	intact-crc:B52113C56DB7E369|rigid:Rq472ti3Fh+ZBVW5tCcxmNtu0/I	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96BA8	uniprotkb:Q06144	intact:EBI-6942903|ensembl:ENSP00000481956|intact:MINT-268046|intact:MINT-8162577|uniprotkb:Q8N2D5|uniprotkb:Q96CP0	intact:EBI-34916|uniprotkb:D6VYY8|ensemblfungi:YLR350W	psi-mi:cr3l1_human(display_long)|uniprotkb:CREB3L1(gene name)|psi-mi:CREB3L1(display_short)|uniprotkb:OASIS(gene name synonym)|uniprotkb:PSEC0238(orf name)|uniprotkb:Old astrocyte specifically-induced substance(gene name synonym)	psi-mi:orm2_yeast(display_long)|uniprotkb:ORM2(gene name)|psi-mi:ORM2(display_short)|uniprotkb:YLR350W(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11535542|imex:IM-24995-1383	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157613(gene)|ensembl:ENST00000621158(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0070278"(extracellular matrix constituent secretion)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029805|mint:Q96BA8|reactome:R-HSA-8874211|refseq:NP_443086.1|entrezgene/locuslink:90993(identity)	refseq:NP_013454.1|sgd:S000004342|mint:Q06144|dip:DIP-5579N|ensemblfungi:YLR350W(gene)|ensemblfungi:YLR350W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035339"(SPOTS complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0090155"(negative regulation of sphingolipid biosynthetic process)|go:"GO:0090156"(cellular sphingolipid homeostasis)|go:"GO:1900060"(negative regulation of ceramide biosynthetic process)|interpro:IPR007203(ORMDL)|reactome:R-SCE-6798695|sgd:YLR350W(identity)	-	comment:mint|function:"Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE"	crc64:2F474503CAB7C195	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:sMWUFmBeBBCO+T0Y2CuB/un1lBg9606	rogid:sY9Jt1Ogpw+lL+9cnBqUeXBiBdE559292	intact-crc:E97464606118ACCC|rigid:6cdPaXf69FAZGGC+M/4eauab+6w	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96MF2	uniprotkb:Q06132	intact:EBI-745680|uniprotkb:B4DUK9|uniprotkb:Q96HU5|ensembl:ENSP00000329200	intact:EBI-34377|uniprotkb:D6VYX6|ensemblfungi:YLR336C	psi-mi:stac3_human(display_long)|uniprotkb:STAC3(gene name)|psi-mi:STAC3(display_short)	psi-mi:sgd1_yeast(display_long)|uniprotkb:SGD1(gene name)|psi-mi:SGD1(display_short)|uniprotkb:YLR336C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11535531|imex:IM-24995-1382	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001273185.1|refseq:NP_001273186.1|refseq:NP_659501.1|refseq:XP_011536428.1|ensembl:ENSG00000185482(gene)|ensembl:ENST00000332782(transcript)|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0030315"(T-tubule)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:1901387"(positive regulation of voltage-gated calcium channel activity)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|interpro:IPR001452(Src homology-3)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR035736|interpro:IPR036028|interpro:IPR039688|mint:Q96MF2|rcsb pdb:2DB6|rcsb pdb:6B29|rcsb pdb:6UY7|rcsb pdb:6UY8|rcsb pdb:6UY9|entrezgene/locuslink:246329(identity)	refseq:NP_013440.1|sgd:S000004328|mint:Q06132|dip:DIP-6333N|ensemblfungi:YLR336C(gene)|ensemblfungi:YLR336C_mRNA(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0006972"(hyperosmotic response)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0097078"(FAL1-SGD1 complex)|interpro:IPR003890(MIF4G-like, type 3)|interpro:IPR003891(Initiation factor eIF-4 gamma, MA3)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR016024(Armadillo-type fold)|sgd:YLR336C(identity)	-	-	crc64:8EEFDB8258407FF3	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:PzyVrp74OzLhtbODzinH5fHSGRc9606	rogid:FxZCxGejbcvEs/J2h1HEaWeVZLQ559292	intact-crc:79643EA139DCC04A|rigid:cHruQ2Bu9L+amyG30Q0+EETJouQ	false	sufficient binding region:40-364	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q06251	uniprotkb:P62258	intact:EBI-32907|uniprotkb:D6VYI1|ensemblfungi:YLR177W	intact:EBI-356498|uniprotkb:P29360|uniprotkb:P42655|uniprotkb:Q53XZ5|uniprotkb:Q63631|uniprotkb:Q7M4R4|uniprotkb:B3KY71|uniprotkb:D3DTH5|uniprotkb:Q4VJB6|ensembl:ENSP00000264335|ensembl:ENSP00000487356	psi-mi:yl177_yeast(display_long)|uniprotkb:YLR177W(locus name)	psi-mi:1433e_human(display_long)|uniprotkb:YWHAE(gene name)|psi-mi:YWHAE(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11535587|imex:IM-24995-1388	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013278.1|sgd:S000004167|mint:Q06251|dip:DIP-4804N|ensemblfungi:YLR177W(gene)|ensemblfungi:YLR177W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|interpro:IPR007557(PSP1 C-terminal conserved region)|sgd:YLR177W(identity)	refseq:NP_006752.1|dip:DIP-36676N|reactome:R-HSA-1445148|reactome:R-HSA-2028269|reactome:R-HSA-205025|reactome:R-HSA-2565942|reactome:R-HSA-3371453|reactome:R-HSA-3371511|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-75035|reactome:R-HSA-8854518|reactome:R-HSA-8862803|reactome:R-HSA-8876198|ensembl:ENSG00000108953(gene)|ensembl:ENSG00000274474(gene)|ensembl:ENST00000264335(transcript)|ensembl:ENST00000627231(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0003064"(regulation of heart rate by hormone)|go:"GO:0003723"(RNA binding)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005925"(focal adhesion)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050815"(phosphoserine residue binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099072"(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:"GO:1901016"(regulation of potassium ion transmembrane transporter activity)|go:"GO:1901020"(negative regulation of calcium ion transmembrane transporter activity)|go:"GO:1902309"(negative regulation of peptidyl-serine dephosphorylation)|go:"GO:1905913"(negative regulation of calcium ion export across plasma membrane)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P62258|rcsb pdb:2BR9|rcsb pdb:3UAL|rcsb pdb:3UBW|rcsb pdb:6EIH|rcsb pdb:7C8E|reactome:R-HSA-111447|entrezgene/locuslink:7531(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:24pYGcKZbt39dfb9ITA+NxFPo0Y559292	rogid:mnuAjdnQZbMFojll2PnV3xFklXQ9606	intact-crc:9D5F207F14423ECC|rigid:i2S8lHUrARRRAcIR3XbOtl9ht4o	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38159	uniprotkb:Q06251	intact:EBI-743526|ensembl:ENSP00000359645|uniprotkb:Q5JQ67|uniprotkb:Q969R3|uniprotkb:D3DWH0|uniprotkb:E9PG86|uniprotkb:Q8N8Y7|uniprotkb:B4E3U4	intact:EBI-32907|uniprotkb:D6VYI1|ensemblfungi:YLR177W	psi-mi:rbmx_human(display_long)|uniprotkb:Glycoprotein p43(gene name synonym)|uniprotkb:RBMX(gene name)|psi-mi:RBMX(display_short)|uniprotkb:HNRPG(gene name synonym)|uniprotkb:RBMXP1(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein G(gene name synonym)	psi-mi:yl177_yeast(display_long)|uniprotkb:YLR177W(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11535578|imex:IM-24995-1387	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000147274(gene)|ensembl:ENST00000320676(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000791"(euchromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0044530"(supraspliceosomal complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0006509"(membrane protein ectodomain proteolysis)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012604(RBM1CTR)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|mint:P38159|rcsb pdb:2MB0|rcsb pdb:2MKS|reactome:R-HSA-72163|reactome:R-HSA-72203|reactome:R-HSA-9013418|reactome:R-HSA-9013422|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273|refseq:NP_002130.2|refseq:NP_001158275.1|dip:DIP-34447N|entrezgene/locuslink:27316(identity)	refseq:NP_013278.1|sgd:S000004167|mint:Q06251|dip:DIP-4804N|ensemblfungi:YLR177W(gene)|ensemblfungi:YLR177W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|interpro:IPR007557(PSP1 C-terminal conserved region)|sgd:YLR177W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:ocCkdy9PxjeVLUQf0tMVCEhFfO89606	rogid:24pYGcKZbt39dfb9ITA+NxFPo0Y559292	intact-crc:E3D5162046C28727|rigid:rSwQZlrHqP4qnxoHvnar+f6S5+I	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q06178	uniprotkb:Q9HAN9	intact:EBI-11803|ensemblfungi:YLR328W|uniprotkb:D6VYX0	intact:EBI-3917542|uniprotkb:Q8TAE9|uniprotkb:Q9H6B6|uniprotkb:Q9H247|uniprotkb:B1AN63|ensembl:ENSP00000366410|ensembl:ENSP00000435134	psi-mi:nma1_yeast(display_long)|uniprotkb:NMA1(gene name)|psi-mi:NMA1(display_short)|uniprotkb:"NAD(+) pyrophosphorylase 1"(gene name synonym)|uniprotkb:"NAD(+) diphosphorylase 1"(gene name synonym)|uniprotkb:Nicotinamide-nucleotide adenylyltransferase 1(gene name synonym)|uniprotkb:Nicotinate-nucleotide adenylyltransferase 1(gene name synonym)|uniprotkb:L8543.16(orf name)|uniprotkb:YLR328W(locus name)	psi-mi:nmna1_human(display_long)|uniprotkb:NMNAT1(gene name)|psi-mi:NMNAT1(display_short)|uniprotkb:NMNAT(gene name synonym)|uniprotkb:Nicotinate-nucleotide adenylyltransferase 1(gene name synonym)|uniprotkb:Nicotinamide-nucleotide adenylyltransferase 1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11535569|imex:IM-24995-1386	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YLR328W(gene)|ensemblfungi:YLR328W_mRNA(transcript)|go:"GO:0000309"(nicotinamide-nucleotide adenylyltransferase activity)|go:"GO:0004515"(nicotinate-nucleotide adenylyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009435"(NAD biosynthetic process)|go:"GO:0042802"(identical protein binding)|interpro:IPR004821(Cytidyltransferase-related)|interpro:IPR005248(Probable nicotinate-nucleotide adenylyltransferase)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|reactome:R-SCE-196807|refseq:NP_013432.1|sgd:S000004320|dip:DIP-1228N|mint:Q06178|sgd:YLR328W(identity)	refseq:NP_001284707.1|refseq:NP_073624.2|ensembl:ENSG00000173614(gene)|ensembl:ENST00000377205(transcript)|ensembl:ENST00000462686(transcript)|go:"GO:0000309"(nicotinamide-nucleotide adenylyltransferase activity)|go:"GO:0004515"(nicotinate-nucleotide adenylyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0009165"(nucleotide biosynthetic process)|go:"GO:0009435"(NAD biosynthetic process)|go:"GO:0009611"(response to wounding)|go:"GO:0016604"(nuclear body)|go:"GO:0042802"(identical protein binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:1902511"(negative regulation of apoptotic DNA fragmentation)|go:"GO:1990966"(ATP generation from poly-ADP-D-ribose)|interpro:IPR004821(Cytidyltransferase-related)|interpro:IPR005248(Probable nicotinate-nucleotide adenylyltransferase)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|mint:Q9HAN9|rcsb pdb:1GZU|rcsb pdb:1KKU|rcsb pdb:1KQN|rcsb pdb:1KQO|rcsb pdb:1KR2|reactome:R-HSA-196807|refseq:XP_016857596.1|dip:DIP-60881N|entrezgene/locuslink:64802(identity)	-	crc64:A176964E56A30DD8	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:VzrKsykGbQsR8Eh7CHCwn/bCID8559292	rogid:KwV9lz04z3ptlVpKu3b534Yekpc9606	intact-crc:C70D6BE58154EBD0|rigid:7dZJEHyGoAiPQXKWTkcPwt6rJi0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q06178	uniprotkb:P63279	intact:EBI-11803|ensemblfungi:YLR328W|uniprotkb:D6VYX0	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	psi-mi:nma1_yeast(display_long)|uniprotkb:NMA1(gene name)|psi-mi:NMA1(display_short)|uniprotkb:"NAD(+) pyrophosphorylase 1"(gene name synonym)|uniprotkb:"NAD(+) diphosphorylase 1"(gene name synonym)|uniprotkb:Nicotinamide-nucleotide adenylyltransferase 1(gene name synonym)|uniprotkb:Nicotinate-nucleotide adenylyltransferase 1(gene name synonym)|uniprotkb:L8543.16(orf name)|uniprotkb:YLR328W(locus name)	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11535560|imex:IM-24995-1385	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YLR328W(gene)|ensemblfungi:YLR328W_mRNA(transcript)|go:"GO:0000309"(nicotinamide-nucleotide adenylyltransferase activity)|go:"GO:0004515"(nicotinate-nucleotide adenylyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009435"(NAD biosynthetic process)|go:"GO:0042802"(identical protein binding)|interpro:IPR004821(Cytidyltransferase-related)|interpro:IPR005248(Probable nicotinate-nucleotide adenylyltransferase)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|reactome:R-SCE-196807|refseq:NP_013432.1|sgd:S000004320|dip:DIP-1228N|mint:Q06178|sgd:YLR328W(identity)	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N|entrezgene/locuslink:7329(identity)	-	crc64:A176964E56A30DD8	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:VzrKsykGbQsR8Eh7CHCwn/bCID8559292	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	intact-crc:F869D0792F2BA037|rigid:2h914wn3NQRlmLY0vGS3NzozEBE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q86UW9	uniprotkb:Q06389	intact:EBI-740376|uniprotkb:Q96H69|uniprotkb:Q9H890|uniprotkb:Q9P200|uniprotkb:Q6XM88|ensembl:ENSP00000322885|ensembl:ENSP00000390218|ensembl:ENSP00000411986|uniprotkb:Q6XM87|intact:EBI-10192429|uniprotkb:Q4ZH49	intact:EBI-11946|ensemblfungi:YDR373W|uniprotkb:D6VT04	psi-mi:dtx2_human(display_long)|uniprotkb:RING finger protein 58(gene name synonym)|uniprotkb:DTX2(gene name)|psi-mi:DTX2(display_short)|uniprotkb:KIAA1528(gene name synonym)|uniprotkb:RNF58(gene name synonym)|uniprotkb:Protein deltex-2(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase DTX2(gene name synonym)	psi-mi:ncs1_yeast(display_long)|uniprotkb:FRQ1(gene name)|psi-mi:FRQ1(display_short)|uniprotkb:NCS1(gene name synonym)|uniprotkb:YDR373W(locus name)|uniprotkb:D9481.6(orf name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11535624|imex:IM-24995-1392	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001096064.1|refseq:NP_001096065.1|refseq:NP_001096066.1|refseq:NP_065943.2|ensembl:ENSP00000322885|ensembl:ENSP00000390218|ensembl:ENSP00000411986|ensembl:ENST00000446820|ensembl:ENSP00000392545|ensembl:ENSG00000091073(gene)|ensembl:ENST00000324432(transcript)|ensembl:ENST00000413936(transcript)|ensembl:ENST00000430490(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031965"(nuclear membrane)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR004170(WWE)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR018123|interpro:IPR018957|interpro:IPR037197|interpro:IPR039396|interpro:IPR039398|interpro:IPR039399|mint:Q86UW9|rcsb pdb:6IR0|rcsb pdb:6Y22|rcsb pdb:6Y2X|rcsb pdb:6Y3J|reactome:R-HSA-2122948|refseq:XP_011514074.1|refseq:XP_011514075.1|refseq:XP_011514076.1|refseq:XP_011514077.1|refseq:XP_005250188.1|refseq:XP_005250189.1|refseq:XP_016867212.1|refseq:XP_016867213.1|refseq:XP_016867214.1|refseq:XP_016867215.1|refseq:XP_016867216.1|entrezgene/locuslink:113878(identity)	ensemblfungi:YDR373W(gene)|ensemblfungi:YDR373W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0033101"(cellular bud membrane)|go:"GO:0043128"(positive regulation of 1-phosphatidylinositol 4-kinase activity)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR028846|rcsb pdb:1FPW|rcsb pdb:2JU0|reactome:R-SCE-2514859|refseq:NP_010661.3|sgd:S000002781|mint:Q06389|dip:DIP-2733N|sgd:YDR373W(identity)	-	-	crc64:5E9D7F48F8AADA21	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:ugnjqAbG6Ekyc8MGugCnjc9zVaI9606	rogid:8mxxTP8CHNx24fQcjCxgDE7xhbs559292	intact-crc:19DB28455F0E3BCE|rigid:3wWYrx4hFjPIVMUN/p7zZOP9Wqg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q06389	uniprotkb:P01011	intact:EBI-11946|ensemblfungi:YDR373W|uniprotkb:D6VT04	intact:EBI-296557|uniprotkb:Q9UC47|uniprotkb:Q13703|uniprotkb:Q2TU87|uniprotkb:Q2TU88|uniprotkb:Q59GP9|uniprotkb:Q6LBY8|uniprotkb:Q6LDT7|uniprotkb:Q6NSC9|uniprotkb:Q8N177|uniprotkb:Q96DW8|uniprotkb:Q9UNU9|uniprotkb:B3KVQ7|ensembl:ENSP00000376793|ensembl:ENSP00000376795|ensembl:ENSP00000450540	psi-mi:ncs1_yeast(display_long)|uniprotkb:FRQ1(gene name)|psi-mi:FRQ1(display_short)|uniprotkb:NCS1(gene name synonym)|uniprotkb:YDR373W(locus name)|uniprotkb:D9481.6(orf name)	psi-mi:aact_human(display_long)|uniprotkb:Cell growth-inhibiting gene 24/25 protein(gene name synonym)|uniprotkb:SERPINA3(gene name)|psi-mi:SERPINA3(display_short)|uniprotkb:AACT(gene name synonym)|uniprotkb:GIG24(orf name)|uniprotkb:GIG25(orf name)|uniprotkb:Serpin A3(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11535614|imex:IM-24995-1391	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YDR373W(gene)|ensemblfungi:YDR373W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0033101"(cellular bud membrane)|go:"GO:0043128"(positive regulation of 1-phosphatidylinositol 4-kinase activity)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR028846|rcsb pdb:1FPW|rcsb pdb:2JU0|reactome:R-SCE-2514859|refseq:NP_010661.3|sgd:S000002781|mint:Q06389|dip:DIP-2733N|sgd:YDR373W(identity)	go:"GO:0006953"(acute-phase response)|refseq:NP_001076.2|ensembl:ENSG00000196136(gene)|ensembl:ENST00000393078(transcript)|ensembl:ENST00000393080(transcript)|ensembl:ENST00000467132(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|reactome:R-HSA-6798695|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0030277"(maintenance of gastrointestinal epithelium)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|interpro:IPR000215(Protease inhibitor I4, serpin)|go:"GO:0006954"(inflammatory response)|interpro:IPR023795|interpro:IPR023796|go:"GO:0010951"(negative regulation of endopeptidase activity)|interpro:IPR036186|interpro:IPR042178|interpro:IPR042185|mint:P01011|rcsb pdb:1AS4|rcsb pdb:1QMN|rcsb pdb:2ACH|rcsb pdb:3CAA|rcsb pdb:3DLW|rcsb pdb:4CAA|rcsb pdb:6HGE|reactome:R-HSA-114608|entrezgene/locuslink:12(identity)	-	crc64:5E9D7F48F8AADA21	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:8mxxTP8CHNx24fQcjCxgDE7xhbs559292	rogid:LTdrRsWwtOm8QvOWZ4h0SO8EuP09606	intact-crc:7AADF5D29E8F0712|rigid:n9tp04GjADA1tlOpNF09vF0RG90	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P63279	uniprotkb:Q06340	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	intact:EBI-33799|uniprotkb:D6VSZ1|ensemblfungi:YDR363W	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:esc2_yeast(display_long)|uniprotkb:YDR363W(locus name)|uniprotkb:ESC2(gene name)|psi-mi:ESC2(display_short)|uniprotkb:Establishes silent chromatin protein 2(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11535605|imex:IM-24995-1390	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N|entrezgene/locuslink:7329(identity)	refseq:NP_010650.1|sgd:S000002771|dip:DIP-5219N|ensemblfungi:YDR363W(gene)|ensemblfungi:YDR363W_mRNA(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0033235"(positive regulation of protein sumoylation)|interpro:IPR000626(Ubiquitin)|interpro:IPR022617|interpro:IPR029071|sgd:YDR363W(identity)	-	-	crc64:F691FB73ED2FAF15	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	rogid:LgEXHq17g/of0LB8TeMRHcceivk559292	intact-crc:A5A7E911698D208A|rigid:RE7bWgGGogHJBLPghe37QCyAJF4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O15209	uniprotkb:Q06287	intact:EBI-723574|uniprotkb:Q5HYV4|uniprotkb:Q5STL0|uniprotkb:Q5STR7|uniprotkb:Q8WV82|ensembl:ENSP00000372683|ensembl:ENSP00000388191|ensembl:ENSP00000393514|ensembl:ENSP00000396292|ensembl:ENSP00000404403|ensembl:ENSP00000407545|uniprotkb:B0V007	intact:EBI-11979|ensemblfungi:YLR186W|uniprotkb:E9P8U2|uniprotkb:D6VYI9	psi-mi:zbt22_human(display_long)|uniprotkb:Zinc finger protein 297(gene name synonym)|uniprotkb:Protein BING1(gene name synonym)|uniprotkb:Zinc finger and BTB domain-containing protein 22A(gene name synonym)|uniprotkb:ZBTB22(gene name)|psi-mi:ZBTB22(display_short)|uniprotkb:BING1(gene name synonym)|uniprotkb:ZBTB22A(gene name synonym)|uniprotkb:ZNF297(gene name synonym)	psi-mi:nep1_yeast(display_long)|uniprotkb:EMG1(gene name)|psi-mi:EMG1(display_short)|uniprotkb:NEP1(gene name synonym)|uniprotkb:YLR186W(locus name)|uniprotkb:L9470.5(orf name)|uniprotkb:Nucleolar essential protein 1(gene name synonym)|uniprotkb:"18S rRNA (pseudouridine(1189)-N1)-methyltransferase"(gene name synonym)|uniprotkb:Essential for mitotic growth protein 1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11535596|imex:IM-24995-1389	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001138810.1|refseq:NP_005444.4|ensembl:ENSG00000206280(gene)|ensembl:ENSG00000227780(gene)|ensembl:ENSG00000229253(gene)|ensembl:ENSG00000236104(gene)|ensembl:ENSG00000237056(gene)|ensembl:ENST00000418724(transcript)|ensembl:ENST00000431845(transcript)|ensembl:ENST00000445320(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR029833|interpro:IPR036236|ensembl:ENST00000383196(transcript)|ensembl:ENST00000416097(transcript)|ensembl:ENST00000418540(transcript)|dip:DIP-62047N|entrezgene/locuslink:9278(identity)	go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005880"(nuclear microtubule)|go:"GO:0006364"(rRNA processing)|go:"GO:0019843"(rRNA binding)|go:"GO:0030686"(90S preribosome)|go:"GO:0031167"(rRNA methylation)|go:"GO:0032040"(small-subunit processome)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0070037"("rRNA (pseudouridine) methyltransferase activity")|go:"GO:0070475"(rRNA base methylation)|interpro:IPR005304(Suppressor Mra1)|ensemblfungi:YLR186W(gene)|interpro:IPR029026|interpro:IPR029028|rcsb pdb:2V3J|rcsb pdb:2V3K|ensemblfungi:YLR186W_mRNA(transcript)|go:"GO:0000447"("endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000472"("endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000480"("endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0005634"(nucleus)|rcsb pdb:3OIJ|rcsb pdb:3OIN|rcsb pdb:5JPQ|rcsb pdb:5TZS|rcsb pdb:5WLC|rcsb pdb:5WYJ|rcsb pdb:5WYK|rcsb pdb:6KE6|rcsb pdb:6LQP|rcsb pdb:6LQQ|rcsb pdb:6LQR|rcsb pdb:6LQS|rcsb pdb:6LQT|rcsb pdb:6LQU|rcsb pdb:3OII|rcsb pdb:6LQV|rcsb pdb:6ZQA|rcsb pdb:6ZQB|rcsb pdb:6ZQC|rcsb pdb:6ZQD|rcsb pdb:6ZQE|rcsb pdb:6ZQF|rcsb pdb:6ZQG|rcsb pdb:7AJT|rcsb pdb:7AJU|sgd:S000004176|refseq:NP_013287.1|reactome:R-SCE-6791226|dip:DIP-6504N|sgd:YLR186W(identity)	-	-	crc64:4A8FCDA812051AD1	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:/u3Is9uJ0nS5Ru7xZKg4MqF6dzE9606	rogid:z62Fg9aJ4kKGgU5NIlAND2yHGrQ559292	intact-crc:E30981197FFC95A7|rigid:UMN0yqxmM5sRZxe9fSOd2ELtnJY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q05D60	uniprotkb:Q06411	intact:EBI-748597|uniprotkb:Q8NEF1|uniprotkb:Q96LL7|intact:EBI-10177066|uniprotkb:E9PJR5|ensembl:ENSP00000298050	intact:EBI-576|uniprotkb:D6VZ60|ensemblfungi:YLR424W	psi-mi:deup1_human(display_long)|uniprotkb:CCDC67(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 67(gene name synonym)|uniprotkb:DEUP1(gene name)|psi-mi:DEUP1(display_short)	psi-mi:sp382_yeast(display_long)|uniprotkb:NTR1(gene name synonym)|uniprotkb:YLR424W(locus name)|uniprotkb:SPP382(gene name)|psi-mi:SPP382(display_short)|uniprotkb:CCF8(gene name synonym)|uniprotkb:Suppressor of PRP38 protein 2(gene name synonym)|uniprotkb:Nineteen complex-related protein 1(gene name synonym)|uniprotkb:CLF1 complex factor 8(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11535652|imex:IM-24995-1395	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_857596.2|refseq:XP_005273859.1|ensembl:ENSG00000165325(gene)|ensembl:ENST00000298050(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005814"(centriole)|go:"GO:0007099"(centriole replication)|go:"GO:0042802"(identical protein binding)|go:"GO:0098535"(de novo centriole assembly involved in multi-ciliated epithelial cell differentiation)|go:"GO:0098536"(deuterosome)|go:"GO:1903251"(multi-ciliated epithelial cell differentiation)|interpro:IPR029611|interpro:IPR031470|go:"GO:0030030"(cell projection organization)|entrezgene/locuslink:159989(identity)	refseq:NP_013528.1|sgd:S000004416|dip:DIP-1491N|mint:Q06411|ensemblfungi:YLR424W(gene)|ensemblfungi:YLR424W_mRNA(transcript)|go:"GO:0000349"(generation of catalytic spliceosome for first transesterification step)|go:"GO:0000390"(spliceosomal complex disassembly)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0071008"(U2-type post-mRNA release spliceosomal complex)|go:"GO:1904876"(negative regulation of DNA ligase activity)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR000467(D111/G-patch)|rcsb pdb:5Y88|sgd:YLR424W(identity)	-	-	crc64:9986B547B9582338	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:/d2HVFtI68hr7u7nqJdBUwn06bE9606	rogid:HrG54vTE2zs7jxPSzi+9eeA23/k559292	intact-crc:BDCB283FC0A203FD|rigid:8PqKGM3lyIAAkFS+iM5UgSYr6zg	false	sufficient binding region:265-604	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38432	uniprotkb:Q06411	intact:EBI-945751|uniprotkb:B2R931|ensembl:ENSP00000240316	intact:EBI-576|uniprotkb:D6VZ60|ensemblfungi:YLR424W	psi-mi:coil_human(display_long)|uniprotkb:COIL(gene name)|psi-mi:COIL(display_short)|uniprotkb:CLN80(gene name synonym)|uniprotkb:p80-coilin(gene name synonym)	psi-mi:sp382_yeast(display_long)|uniprotkb:NTR1(gene name synonym)|uniprotkb:YLR424W(locus name)|uniprotkb:SPP382(gene name)|psi-mi:SPP382(display_short)|uniprotkb:CCF8(gene name synonym)|uniprotkb:Suppressor of PRP38 protein 2(gene name synonym)|uniprotkb:Nineteen complex-related protein 1(gene name synonym)|uniprotkb:CLF1 complex factor 8(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11535643|imex:IM-24995-1394	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004636.1|dip:DIP-38503N|ensembl:ENSG00000121058(gene)|ensembl:ENST00000240316(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0015030"(Cajal body)|go:"GO:0016020"(membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0030619"(U1 snRNA binding)|go:"GO:0030620"(U2 snRNA binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR024822|interpro:IPR031722|mint:P38432|entrezgene/locuslink:8161(identity)	refseq:NP_013528.1|sgd:S000004416|dip:DIP-1491N|mint:Q06411|ensemblfungi:YLR424W(gene)|ensemblfungi:YLR424W_mRNA(transcript)|go:"GO:0000349"(generation of catalytic spliceosome for first transesterification step)|go:"GO:0000390"(spliceosomal complex disassembly)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0071008"(U2-type post-mRNA release spliceosomal complex)|go:"GO:1904876"(negative regulation of DNA ligase activity)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR000467(D111/G-patch)|rcsb pdb:5Y88|sgd:YLR424W(identity)	-	-	crc64:9986B547B9582338	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:hd5p6AbyA/GYNEeca99Mdb41qM09606	rogid:HrG54vTE2zs7jxPSzi+9eeA23/k559292	intact-crc:6D3A8F526DE9B870|rigid:kt448FdSg/2TjseZenFZiXDSbyE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O75071	uniprotkb:Q06408	intact:EBI-2805635|ensembl:ENSP00000361001|uniprotkb:Q5SXB8|uniprotkb:D3DQ23	intact:EBI-32807|uniprotkb:D6VT13|ensemblfungi:YDR380W	psi-mi:efc14_human(display_long)|uniprotkb:EFCAB14(gene name)|psi-mi:EFCAB14(display_short)|uniprotkb:KIAA0494(gene name synonym)	psi-mi:aro10_yeast(display_long)|uniprotkb:ARO10(gene name)|psi-mi:ARO10(display_short)|uniprotkb:YDR380W(locus name)|uniprotkb:D9481.3(orf name)|uniprotkb:Transaminated branched-chain amino acid decarboxylase(gene name synonym)|uniprotkb:Thiamine diphosphate-dependent phenylpyruvate decarboxylase(gene name synonym)|uniprotkb:Thiamine pyrophosphate-dependent 2-oxo-acid decarboxylase(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11535634|imex:IM-24995-1393	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000159658(gene)|ensembl:ENST00000371933(transcript)|go:"GO:0005509"(calcium ion binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR042352|refseq:NP_055589.1|entrezgene/locuslink:9813(identity)	sgd:S000002788|refseq:NP_010668.3|dip:DIP-5252N|mint:Q06408|ensemblfungi:YDR380W(gene)|ensemblfungi:YDR380W_mRNA(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000949"(aromatic amino acid family catabolic process to alcohol via Ehrlich pathway)|go:"GO:0000950"(branched-chain amino acid catabolic process to alcohol via Ehrlich pathway)|go:"GO:0000951"(methionine catabolic process to 3-methylthiopropanol)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006552"(leucine catabolic process)|go:"GO:0006559"(L-phenylalanine catabolic process)|go:"GO:0006569"(tryptophan catabolic process)|go:"GO:0006572"(tyrosine catabolic process)|go:"GO:0016831"(carboxy-lyase activity)|go:"GO:0030976"(thiamine pyrophosphate binding)|go:"GO:0047433"(branched-chain-2-oxoacid decarboxylase activity)|go:"GO:0047434"(indolepyruvate decarboxylase activity)|go:"GO:0050177"(phenylpyruvate decarboxylase activity)|go:"GO:0050546"(4-hydroxyphenylpyruvate decarboxylase activity)|interpro:IPR011766(Thiamine pyrophosphate enzyme, C-terminal TPP-binding)|interpro:IPR012000(Thiamine pyrophosphate enzyme, central region)|interpro:IPR012001(Thiamine pyrophosphate enzyme, N-terminal TPP binding region)|interpro:IPR012110(Pyruvate decarboxylase/indolepyruvate decarboxylase)|interpro:IPR029035|interpro:IPR029061|sgd:YDR380W(identity)	-	-	crc64:616DF7E06DA82415	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:UhD1cgnq+/XOmI2Y7LZ7ANpf9wA9606	rogid:jh443SvRXK8vb+GUjPq95NB8jdU559292	intact-crc:BAA9A4A3619E24B6|rigid:6mjUoJ6yUoAOiX3za3cyKoGN3Nw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q06411	uniprotkb:Q9NS73-5	intact:EBI-576|uniprotkb:D6VZ60|ensemblfungi:YLR424W	intact:EBI-10182361|ensembl:ENSP00000324444	psi-mi:sp382_yeast(display_long)|uniprotkb:NTR1(gene name synonym)|uniprotkb:YLR424W(locus name)|uniprotkb:SPP382(gene name)|psi-mi:SPP382(display_short)|uniprotkb:CCF8(gene name synonym)|uniprotkb:Suppressor of PRP38 protein 2(gene name synonym)|uniprotkb:Nineteen complex-related protein 1(gene name synonym)|uniprotkb:CLF1 complex factor 8(gene name synonym)	psi-mi:q9ns73-5(display_long)|uniprotkb:MAPK upstream kinase-binding inhibitory protein(gene name synonym)|uniprotkb:BM-015(orf name)|uniprotkb:MBIP(gene name)|psi-mi:MBIP(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11535690|imex:IM-24995-1399	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013528.1|sgd:S000004416|dip:DIP-1491N|mint:Q06411|ensemblfungi:YLR424W(gene)|ensemblfungi:YLR424W_mRNA(transcript)|go:"GO:0000349"(generation of catalytic spliceosome for first transesterification step)|go:"GO:0000390"(spliceosomal complex disassembly)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0071008"(U2-type post-mRNA release spliceosomal complex)|go:"GO:1904876"(negative regulation of DNA ligase activity)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR000467(D111/G-patch)|rcsb pdb:5Y88|sgd:YLR424W(identity)	ensembl:ENSG00000151332(gene)|ensembl:ENST00000318473(transcript)|intact:EBI-741953(isoform-parent)|uniprotkb:Q9NS73-5(isoform-parent)|entrezgene/locuslink:51562(identity)	-	crc64:9986B547B9582338	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:HrG54vTE2zs7jxPSzi+9eeA23/k559292	rogid:JVmcJrT3SXRZwv9U285cNqnXWQE9606	intact-crc:CEE20FAEE1C45DF2|rigid:jFJGl0qhOY6Tud0wyHcxNT3P9XU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9NS73	uniprotkb:Q06411	intact:EBI-741953|uniprotkb:Q86TZ2|uniprotkb:Q96AS5|uniprotkb:Q9BS93|uniprotkb:Q9NZE1|ensembl:ENSP00000399718	intact:EBI-576|uniprotkb:D6VZ60|ensemblfungi:YLR424W	psi-mi:mbip1_human(display_long)|uniprotkb:MAPK upstream kinase-binding inhibitory protein(gene name synonym)|uniprotkb:MBIP(gene name)|psi-mi:MBIP(display_short)|uniprotkb:BM-015(orf name)	psi-mi:sp382_yeast(display_long)|uniprotkb:NTR1(gene name synonym)|uniprotkb:YLR424W(locus name)|uniprotkb:SPP382(gene name)|psi-mi:SPP382(display_short)|uniprotkb:CCF8(gene name synonym)|uniprotkb:Suppressor of PRP38 protein 2(gene name synonym)|uniprotkb:Nineteen complex-related protein 1(gene name synonym)|uniprotkb:CLF1 complex factor 8(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11535681|imex:IM-24995-1398	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001138363.1|refseq:NP_057670.2|ensembl:ENSG00000151332(gene)|ensembl:ENST00000416007(transcript)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0042802"(identical protein binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0046330"(positive regulation of JNK cascade)|interpro:IPR026062|mint:Q9NS73|reactome:R-HSA-3214847|go:"GO:0005654"(nucleoplasm)|refseq:NP_001295039.1|entrezgene/locuslink:51562(identity)	refseq:NP_013528.1|sgd:S000004416|dip:DIP-1491N|mint:Q06411|ensemblfungi:YLR424W(gene)|ensemblfungi:YLR424W_mRNA(transcript)|go:"GO:0000349"(generation of catalytic spliceosome for first transesterification step)|go:"GO:0000390"(spliceosomal complex disassembly)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0071008"(U2-type post-mRNA release spliceosomal complex)|go:"GO:1904876"(negative regulation of DNA ligase activity)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR000467(D111/G-patch)|rcsb pdb:5Y88|sgd:YLR424W(identity)	-	-	crc64:9986B547B9582338	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:PjaEuab6wwOyGImpNYFZfQ+TUvU9606	rogid:HrG54vTE2zs7jxPSzi+9eeA23/k559292	intact-crc:DF7516121EF1C8D5|rigid:8UFlC1frtUrvlYzYlmHIuHNhawM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8NHQ1	uniprotkb:Q06411	intact:EBI-739624|ensembl:ENSP00000264982|ensembl:ENSP00000419231|uniprotkb:Q96B31|uniprotkb:Q9H2C3|uniprotkb:Q9H2Z1|uniprotkb:Q9H940|uniprotkb:D3DNE9|uniprotkb:B7Z5I8|uniprotkb:B7Z7E8|uniprotkb:F5GZX8	intact:EBI-576|uniprotkb:D6VZ60|ensemblfungi:YLR424W	psi-mi:cep70_human(display_long)|uniprotkb:CEP70(gene name)|psi-mi:CEP70(display_short)|uniprotkb:BITE(gene name synonym)|uniprotkb:p10-binding protein(gene name synonym)	psi-mi:sp382_yeast(display_long)|uniprotkb:NTR1(gene name synonym)|uniprotkb:YLR424W(locus name)|uniprotkb:SPP382(gene name)|psi-mi:SPP382(display_short)|uniprotkb:CCF8(gene name synonym)|uniprotkb:Suppressor of PRP38 protein 2(gene name synonym)|uniprotkb:Nineteen complex-related protein 1(gene name synonym)|uniprotkb:CLF1 complex factor 8(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11535672|imex:IM-24995-1397	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114107(gene)|ensembl:ENST00000264982(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|interpro:IPR019734|interpro:IPR037692|mint:Q8NHQ1|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|ensembl:ENST00000484888(transcript)|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_077817.2|refseq:XP_016862764.1|refseq:NP_001275893.1|refseq:NP_001275894.1|refseq:NP_001275895.1|refseq:NP_001275896.1|refseq:NP_001307527.1|refseq:NP_001307529.1|entrezgene/locuslink:80321(identity)	refseq:NP_013528.1|sgd:S000004416|dip:DIP-1491N|mint:Q06411|ensemblfungi:YLR424W(gene)|ensemblfungi:YLR424W_mRNA(transcript)|go:"GO:0000349"(generation of catalytic spliceosome for first transesterification step)|go:"GO:0000390"(spliceosomal complex disassembly)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0071008"(U2-type post-mRNA release spliceosomal complex)|go:"GO:1904876"(negative regulation of DNA ligase activity)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR000467(D111/G-patch)|rcsb pdb:5Y88|sgd:YLR424W(identity)	-	-	crc64:9986B547B9582338	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:S4yveQWcvdVtAUX65gqrJ5Dv0Mc9606	rogid:HrG54vTE2zs7jxPSzi+9eeA23/k559292	intact-crc:E8E00B6F56B5C4F3|rigid:8gVaAftn5+nVBMvX2UnEShT6XlE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q53EZ4	uniprotkb:Q06411	intact:EBI-747776|uniprotkb:Q32WF5|uniprotkb:Q3MV20|uniprotkb:Q5VY28|uniprotkb:Q6N034|ensembl:ENSP00000360540|uniprotkb:Q96H32|uniprotkb:Q9NVS7|uniprotkb:B2RDG8|intact:EBI-10173536|uniprotkb:D3DR37|intact:EBI-28973801	intact:EBI-576|uniprotkb:D6VZ60|ensemblfungi:YLR424W	psi-mi:cep55_human(display_long)|uniprotkb:Up-regulated in colon cancer 6(gene name synonym)|uniprotkb:CEP55(gene name)|psi-mi:CEP55(display_short)|uniprotkb:URCC6(gene name synonym)|uniprotkb:C10orf3(gene name synonym)	psi-mi:sp382_yeast(display_long)|uniprotkb:NTR1(gene name synonym)|uniprotkb:YLR424W(locus name)|uniprotkb:SPP382(gene name)|psi-mi:SPP382(display_short)|uniprotkb:CCF8(gene name synonym)|uniprotkb:Suppressor of PRP38 protein 2(gene name synonym)|uniprotkb:Nineteen complex-related protein 1(gene name synonym)|uniprotkb:CLF1 complex factor 8(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11535663|imex:IM-24995-1396	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001120654.1|refseq:NP_060601.3|ensembl:ENSG00000138180(gene)|ensembl:ENST00000371485(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0014066"(regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0030496"(midbody)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042802"(identical protein binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0061952"(midbody abscission)|go:"GO:0090543"(Flemming body)|go:"GO:1904888"(cranial skeletal system development)|interpro:IPR022008|interpro:IPR038926|mint:Q53EZ4|rcsb pdb:3E1R|rcsb pdb:3WUT|rcsb pdb:3WUU|rcsb pdb:3WUV|go:"GO:0005814"(centriole)|ensembl:ENSP00000360540|dip:DIP-44581N|entrezgene/locuslink:55165(identity)	refseq:NP_013528.1|sgd:S000004416|dip:DIP-1491N|mint:Q06411|ensemblfungi:YLR424W(gene)|ensemblfungi:YLR424W_mRNA(transcript)|go:"GO:0000349"(generation of catalytic spliceosome for first transesterification step)|go:"GO:0000390"(spliceosomal complex disassembly)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0071008"(U2-type post-mRNA release spliceosomal complex)|go:"GO:1904876"(negative regulation of DNA ligase activity)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR000467(D111/G-patch)|rcsb pdb:5Y88|sgd:YLR424W(identity)	-	-	crc64:9986B547B9582338	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:tuo36vVb8ZgPDR81YjZFNEg559w9606	rogid:HrG54vTE2zs7jxPSzi+9eeA23/k559292	intact-crc:C0207D181EABD236|rigid:h0XN/2wUCVo5EFf2F1nVYCyhxCE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q06543	uniprotkb:Q8N5R6	intact:EBI-33132|uniprotkb:D6VYP1|ensemblfungi:YLR243W	intact:EBI-740841|intact:EBI-953781|uniprotkb:B3KQ49|uniprotkb:A8K3U4|uniprotkb:A8MPQ6|uniprotkb:A8MV61|uniprotkb:A8MVU9|uniprotkb:Q9H5Q6|uniprotkb:Q8TAX6|intact:EBI-2320546|intact:EBI-11522976	psi-mi:gpn3_yeast(display_long)|uniprotkb:GPN3(gene name)|psi-mi:GPN3(display_short)|uniprotkb:YLR243W(locus name)	psi-mi:ccd33_human(display_long)|uniprotkb:CCDC33(gene name)|psi-mi:CCDC33(display_short)|uniprotkb:Cancer/testis antigen 61(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11535719|imex:IM-24995-1402	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013344.1|sgd:S000004233|dip:DIP-1911N|ensemblfungi:YLR243W(gene)|ensemblfungi:YLR243W_mRNA(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007064"(mitotic sister chromatid cohesion)|interpro:IPR004130(Protein of unknown function, ATP binding)|interpro:IPR027417|interpro:IPR030228|sgd:YLR243W(identity)	refseq:NP_079331.3|interpro:IPR000008(C2 calcium-dependent membrane targeting)|go:"GO:0005777"(peroxisome)|refseq:NP_001274110.1|refseq:NP_877592.2|mint:Q8N5R6|interpro:IPR035892|interpro:IPR039889|entrezgene/locuslink:80125(identity)	-	crc64:96E478B8DD5988BB	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2021/11/30	rogid:XGJg0/XoYEbfio5kpjB/7Q9Cvjc559292	rogid:eEIn7pQyfdHWx8TeLJpYy0i/gww9606	intact-crc:64560D170102517A|rigid:M7pDBzuMW3ZgO/PQHF9jUqOW4og	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q06411	uniprotkb:Q9UKT9	intact:EBI-576|uniprotkb:D6VZ60|ensemblfungi:YLR424W	intact:EBI-747204|uniprotkb:Q8WWQ9|uniprotkb:Q8WWR0|uniprotkb:Q8WWR1|uniprotkb:Q8WWR2|uniprotkb:Q8WWR3|uniprotkb:Q8N574|uniprotkb:B4DVV5|uniprotkb:Q69BL6|uniprotkb:Q69BL7|uniprotkb:Q69BL8|uniprotkb:Q69BL9|uniprotkb:Q69BM0|uniprotkb:Q69BM1|uniprotkb:Q69BM2|uniprotkb:Q69BM3|uniprotkb:Q69BM5|ensembl:ENSP00000344544	psi-mi:sp382_yeast(display_long)|uniprotkb:NTR1(gene name synonym)|uniprotkb:YLR424W(locus name)|uniprotkb:SPP382(gene name)|psi-mi:SPP382(display_short)|uniprotkb:CCF8(gene name synonym)|uniprotkb:Suppressor of PRP38 protein 2(gene name synonym)|uniprotkb:Nineteen complex-related protein 1(gene name synonym)|uniprotkb:CLF1 complex factor 8(gene name synonym)	psi-mi:ikzf3_human(display_long)|uniprotkb:ZNFN1A3(gene name synonym)|uniprotkb:Ikaros family zinc finger protein 3(gene name synonym)|uniprotkb:IKZF3(gene name)|psi-mi:IKZF3(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11535710|imex:IM-24995-1401	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013528.1|sgd:S000004416|dip:DIP-1491N|mint:Q06411|ensemblfungi:YLR424W(gene)|ensemblfungi:YLR424W_mRNA(transcript)|go:"GO:0000349"(generation of catalytic spliceosome for first transesterification step)|go:"GO:0000390"(spliceosomal complex disassembly)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0071008"(U2-type post-mRNA release spliceosomal complex)|go:"GO:1904876"(negative regulation of DNA ligase activity)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR000467(D111/G-patch)|rcsb pdb:5Y88|sgd:YLR424W(identity)	refseq:NP_001271443.1|refseq:NP_001271444.1|refseq:NP_036613.2|refseq:NP_899051.1|refseq:NP_899052.1|refseq:NP_899053.1|refseq:NP_899054.1|refseq:NP_899055.1|refseq:NP_001271445.1|refseq:NP_001244337.1|refseq:NP_001244338.1|refseq:NP_001244339.1|refseq:NP_001244340.1|refseq:NP_001244341.1|refseq:NP_001244342.1|refseq:NP_001244343.1|ensembl:ENSG00000161405(gene)|ensembl:ENST00000346872(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007498"(mesoderm development)|go:"GO:0009617"(response to bacterium)|go:"GO:0030888"(regulation of B cell proliferation)|go:"GO:0042113"(B cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045577"(regulation of B cell differentiation)|go:"GO:0045619"(regulation of lymphocyte differentiation)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|go:"GO:0046872"(metal ion binding)|dip:DIP-56975N|entrezgene/locuslink:22806(identity)	-	crc64:9986B547B9582338	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:HrG54vTE2zs7jxPSzi+9eeA23/k559292	rogid:2Kp6LefSLfK5VIiE6DmQusFIfMY9606	intact-crc:8AB09A9616AD4B41|rigid:7PHYXTkfUcGLLjnZ7vE+v4asd6U	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q06411	uniprotkb:Q9UJV3-2	intact:EBI-576|uniprotkb:D6VZ60|ensemblfungi:YLR424W	intact:EBI-10172526|ensembl:ENSP00000413976	psi-mi:sp382_yeast(display_long)|uniprotkb:NTR1(gene name synonym)|uniprotkb:YLR424W(locus name)|uniprotkb:SPP382(gene name)|psi-mi:SPP382(display_short)|uniprotkb:CCF8(gene name synonym)|uniprotkb:Suppressor of PRP38 protein 2(gene name synonym)|uniprotkb:Nineteen complex-related protein 1(gene name synonym)|uniprotkb:CLF1 complex factor 8(gene name synonym)	psi-mi:q9ujv3-2(display_long)|uniprotkb:RING-type E3 ubiquitin transferase MID2(gene name synonym)|uniprotkb:FXY2(gene name synonym)|uniprotkb:Midin-2(gene name synonym)|uniprotkb:Midline defect 2(gene name synonym)|uniprotkb:Midline-2(gene name synonym)|uniprotkb:RING finger protein 60(gene name synonym)|uniprotkb:RNF60(gene name synonym)|uniprotkb:TRIM1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 1(gene name synonym)|uniprotkb:MID2(gene name)|psi-mi:MID2(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11535699|imex:IM-24995-1400	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013528.1|sgd:S000004416|dip:DIP-1491N|mint:Q06411|ensemblfungi:YLR424W(gene)|ensemblfungi:YLR424W_mRNA(transcript)|go:"GO:0000349"(generation of catalytic spliceosome for first transesterification step)|go:"GO:0000390"(spliceosomal complex disassembly)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0071008"(U2-type post-mRNA release spliceosomal complex)|go:"GO:1904876"(negative regulation of DNA ligase activity)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR000467(D111/G-patch)|rcsb pdb:5Y88|sgd:YLR424W(identity)	intact:EBI-751983(isoform-parent)|uniprotkb:Q9UJV3-2(isoform-parent)|ensembl:ENSG00000080561(gene)|ensembl:ENST00000443968(transcript)|entrezgene/locuslink:11043(identity)	-	crc64:9986B547B9582338	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:HrG54vTE2zs7jxPSzi+9eeA23/k559292	rogid:/FJ+V2H7SaWon7caUWkEkmHFVxQ9606	intact-crc:82C79F8AFBF0B37D|rigid:aCrhFYu1TtUd69F8tpEKOaWJIBc	false	-	sufficient binding region:21-705	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8N6L0	uniprotkb:Q06616	intact:EBI-749265|uniprotkb:Q96MC3|ensembl:ENSP00000404220	intact:EBI-36065|uniprotkb:D6W4H5|ensemblfungi:YPR174C	psi-mi:kash5_human(display_long)|uniprotkb:KASH5(gene name)|psi-mi:KASH5(display_short)|uniprotkb:CCDC155(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 155(gene name synonym)|uniprotkb:KASH domain-containing protein 5(gene name synonym)	psi-mi:yp174_yeast(display_long)|uniprotkb:YPR174C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11535750|imex:IM-24995-1405	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_653289.3|ensembl:ENSG00000161609(gene)|ensembl:ENST00000447857(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034397"(telomere localization)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051225"(spindle assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0090172"(microtubule cytoskeleton organization involved in homologous chromosome segregation)|go:"GO:0090220"(chromosome localization to nuclear envelope involved in homologous chromosome segregation)|go:"GO:0090619"(meiotic spindle pole)|interpro:IPR011992(EF-Hand type)|interpro:IPR028168|interpro:IPR028170|interpro:IPR039508|mint:Q8N6L0|rcsb pdb:6R2I|rcsb pdb:6WMF|entrezgene/locuslink:147872(identity)	refseq:NP_015500.1|sgd:S000006378|dip:DIP-3800N|ensemblfungi:YPR174C(gene)|ensemblfungi:YPR174C_mRNA(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034399"(nuclear periphery)|interpro:IPR013743(Nap binding NBP1, fungi)|sgd:YPR174C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Wl9L7AcvDHCZuKjYLn8QgGIbZTc9606	rogid:R+7auDlEsOm+VR9gJ1jZsF3ST88559292	intact-crc:CDA03BAB945423D4|rigid:HcU2H04ieLvzvIfH30kFyH3R7o0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q06616	uniprotkb:Q5SW96	intact:EBI-36065|uniprotkb:D6W4H5|ensemblfungi:YPR174C	intact:EBI-747813|uniprotkb:A2BHI5|uniprotkb:Q6TQS9|uniprotkb:Q8N2Y0|uniprotkb:Q9UFI9|intact:EBI-28971912|ensembl:ENSP00000363458	psi-mi:yp174_yeast(display_long)|uniprotkb:YPR174C(locus name)	psi-mi:arh_human(display_long)|uniprotkb:Autosomal recessive hypercholesterolemia protein(gene name synonym)|uniprotkb:LDLRAP1(gene name)|psi-mi:LDLRAP1(display_short)|uniprotkb:ARH(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11535739|imex:IM-24995-1404	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015500.1|sgd:S000006378|dip:DIP-3800N|ensemblfungi:YPR174C(gene)|ensemblfungi:YPR174C_mRNA(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034399"(nuclear periphery)|interpro:IPR013743(Nap binding NBP1, fungi)|sgd:YPR174C(identity)	ensembl:ENSP00000363458|refseq:NP_056442.2|go:"GO:0042982"(amyloid precursor protein metabolic process)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0055037"(recycling endosome)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0090118"(receptor-mediated endocytosis involved in cholesterol transport)|go:"GO:0090205"(positive regulation of cholesterol metabolic process)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905581"(positive regulation of low-density lipoprotein particle clearance)|go:"GO:1905602"(positive regulation of receptor-mediated endocytosis involved in cholesterol transport)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|rcsb pdb:2G30|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8964026|reactome:R-HSA-8964038|ensembl:ENSG00000157978(gene)|ensembl:ENST00000374338(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005883"(neurofilament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030276"(clathrin binding)|go:"GO:0030301"(cholesterol transport)|go:"GO:0030424"(axon)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031623"(receptor internalization)|go:"GO:0034383"(low-density lipoprotein particle clearance)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0035612"(AP-2 adaptor complex binding)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0035650"(AP-1 adaptor complex binding)|go:"GO:0042632"(cholesterol homeostasis)|entrezgene/locuslink:26119(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:R+7auDlEsOm+VR9gJ1jZsF3ST88559292	rogid:dtBWLcVpVD/R0aKQZr9Nucfa1oo9606	intact-crc:3E43748CC0748847|rigid:PTA3oZL7c7aWBEoYMxjMcJObqJA	false	-	sufficient binding region:46-308	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8N0S2	uniprotkb:Q06543	intact:EBI-6872807|ensembl:ENSP00000341282|uniprotkb:Q9BWU4|uniprotkb:B2RC80|uniprotkb:Q9BWU3	intact:EBI-33132|uniprotkb:D6VYP1|ensemblfungi:YLR243W	psi-mi:syce1_human(display_long)|uniprotkb:C10orf94(gene name synonym)|uniprotkb:Cancer/testis antigen 76(gene name synonym)|uniprotkb:SYCE1(gene name)|psi-mi:SYCE1(display_short)	psi-mi:gpn3_yeast(display_long)|uniprotkb:GPN3(gene name)|psi-mi:GPN3(display_short)|uniprotkb:YLR243W(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11535728|imex:IM-24995-1403	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000171772(gene)|ensembl:ENST00000343131(transcript)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0000801"(central element)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051301"(cell division)|interpro:IPR026676|reactome:R-HSA-1221632|refseq:NP_001137235.1|refseq:NP_570140.1|entrezgene/locuslink:93426(identity)	refseq:NP_013344.1|sgd:S000004233|dip:DIP-1911N|ensemblfungi:YLR243W(gene)|ensemblfungi:YLR243W_mRNA(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007064"(mitotic sister chromatid cohesion)|interpro:IPR004130(Protein of unknown function, ATP binding)|interpro:IPR027417|interpro:IPR030228|sgd:YLR243W(identity)	-	-	crc64:96E478B8DD5988BB	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:qLVqIlFiwZJHFfoyYXV3jrqdd609606	rogid:XGJg0/XoYEbfio5kpjB/7Q9Cvjc559292	intact-crc:624C4C59B1B112E1|rigid:nA5S7YO2+jToqKP3IVfrj1+eboU	false	sufficient binding region:37-351	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O15156-2	uniprotkb:Q06630	intact:EBI-11522250|ensembl:ENSP00000406286	intact:EBI-36794|uniprotkb:D6VSS5|ensemblfungi:YDR296W	psi-mi:o15156-2(display_long)|uniprotkb:ZBTB7B(gene name)|psi-mi:ZBTB7B(display_short)|uniprotkb:Krueppel-related zinc finger protein cKrox(gene name synonym)|uniprotkb:T-helper-inducing POZ/Krueppel-like factor(gene name synonym)|uniprotkb:ZBTB15(gene name synonym)|uniprotkb:ZFP67(gene name synonym)|uniprotkb:ZNF857B(gene name synonym)|uniprotkb:Zinc finger and BTB domain-containing protein 15(gene name synonym)|uniprotkb:Zinc finger protein 67 homolog(gene name synonym)|uniprotkb:Zinc finger protein 857B(gene name synonym)|uniprotkb:Zinc finger protein Th-POK(gene name synonym)	psi-mi:mhr1_yeast(display_long)|uniprotkb:MHR1(gene name)|psi-mi:MHR1(display_short)|uniprotkb:YDR296W(locus name)|uniprotkb:Cross-linked transcription component 1(gene name synonym)|uniprotkb:XTC1(gene name synonym)|uniprotkb:Mitochondrial large ribosomal subunit protein mL67(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11535788|imex:IM-24995-1409	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-740434(isoform-parent)|ensembl:ENSG00000160685(gene)|ensembl:ENST00000417934(transcript)|uniprotkb:O15156-2(isoform-parent)|entrezgene/locuslink:51043(identity)	sgd:S000002704|refseq:NP_010582.3|mint:Q06630|dip:DIP-5727N|ensemblfungi:YDR296W(gene)|ensemblfungi:YDR296W_mRNA(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0000150"(DNA strand exchange activity)|go:"GO:0003677"(DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0006310"(DNA recombination)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0032543"(mitochondrial translation)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0090297"(positive regulation of mitochondrial DNA replication)|interpro:IPR024629|rcsb pdb:3J6B|rcsb pdb:5MRC|rcsb pdb:5MRE|rcsb pdb:5MRF|sgd:YDR296W(identity)	-	isoform-comment:No experimental confirmation available.	crc64:F26903A4814091C4	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:41NEFYyprTXI+fOHVFh78TPKF289606	rogid:eA38S7UNOpP716XSQ0zzhYm2TqA559292	intact-crc:EC42FF9C3D2F3813|rigid:+gIfruCDlLpKi5ABf+MA+5VAKWI	false	sufficient binding region:35-573	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O14641	uniprotkb:Q06630	intact:EBI-740850|ensembl:ENSP00000005340|uniprotkb:Q53XM0|uniprotkb:D3DTN3	intact:EBI-36794|uniprotkb:D6VSS5|ensemblfungi:YDR296W	psi-mi:dvl2_human(display_long)|uniprotkb:DSH homolog 2(gene name synonym)|uniprotkb:DVL2(gene name)|psi-mi:DVL2(display_short)	psi-mi:mhr1_yeast(display_long)|uniprotkb:MHR1(gene name)|psi-mi:MHR1(display_short)|uniprotkb:YDR296W(locus name)|uniprotkb:Cross-linked transcription component 1(gene name synonym)|uniprotkb:XTC1(gene name synonym)|uniprotkb:Mitochondrial large ribosomal subunit protein mL67(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11535779|imex:IM-24995-1408	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004413.1|ensembl:ENSG00000004975(gene)|ensembl:ENST00000005340(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005109"(frizzled binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0007507"(heart development)|go:"GO:0016235"(aggresome)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044340"(canonical Wnt signaling pathway involved in regulation of cell proliferation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0150012"(positive regulation of neuron projection arborization)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008341(Dishevelled-2 region)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:O14641|rcsb pdb:2REY|rcsb pdb:3CBX|rcsb pdb:3CBY|rcsb pdb:3CBZ|rcsb pdb:3CC0|rcsb pdb:4WIP|rcsb pdb:5LNP|rcsb pdb:5SUY|rcsb pdb:5SUZ|rcsb pdb:6IW3|rcsb pdb:6JCK|reactome:R-HSA-201681|reactome:R-HSA-201688|reactome:R-HSA-2028269|reactome:R-HSA-4086400|reactome:R-HSA-4608870|reactome:R-HSA-4641258|reactome:R-HSA-4641262|reactome:R-HSA-5099900|reactome:R-HSA-5368598|reactome:R-HSA-5663220|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9673324|ensembl:ENSP00000005340|dip:DIP-34433N|entrezgene/locuslink:1856(identity)	sgd:S000002704|refseq:NP_010582.3|mint:Q06630|dip:DIP-5727N|ensemblfungi:YDR296W(gene)|ensemblfungi:YDR296W_mRNA(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0000150"(DNA strand exchange activity)|go:"GO:0003677"(DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0006310"(DNA recombination)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0032543"(mitochondrial translation)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0090297"(positive regulation of mitochondrial DNA replication)|interpro:IPR024629|rcsb pdb:3J6B|rcsb pdb:5MRC|rcsb pdb:5MRE|rcsb pdb:5MRF|sgd:YDR296W(identity)	-	-	crc64:F26903A4814091C4	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:2Vdc8oRnT4Mz/j+EXQXrL3AszOc9606	rogid:eA38S7UNOpP716XSQ0zzhYm2TqA559292	intact-crc:62E1A43D712985F8|rigid:KfACV2u1KAa7GX/3udfMqHYgtRY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q08379	uniprotkb:Q06630	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	intact:EBI-36794|uniprotkb:D6VSS5|ensemblfungi:YDR296W	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:mhr1_yeast(display_long)|uniprotkb:MHR1(gene name)|psi-mi:MHR1(display_short)|uniprotkb:YDR296W(locus name)|uniprotkb:Cross-linked transcription component 1(gene name synonym)|uniprotkb:XTC1(gene name synonym)|uniprotkb:Mitochondrial large ribosomal subunit protein mL67(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11535768|imex:IM-24995-1407	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N|entrezgene/locuslink:2801(identity)	sgd:S000002704|refseq:NP_010582.3|mint:Q06630|dip:DIP-5727N|ensemblfungi:YDR296W(gene)|ensemblfungi:YDR296W_mRNA(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0000150"(DNA strand exchange activity)|go:"GO:0003677"(DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0006310"(DNA recombination)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0032543"(mitochondrial translation)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0090297"(positive regulation of mitochondrial DNA replication)|interpro:IPR024629|rcsb pdb:3J6B|rcsb pdb:5MRC|rcsb pdb:5MRE|rcsb pdb:5MRF|sgd:YDR296W(identity)	-	-	crc64:F26903A4814091C4	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2017/05/26	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	rogid:eA38S7UNOpP716XSQ0zzhYm2TqA559292	intact-crc:A4BDA01292EFFD01|rigid:gl2QUcrSam/JZf9Zt3jttWwEaDQ	false	sufficient binding region:383-1002	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q969F0	uniprotkb:Q06616	intact:EBI-743099|ensembl:ENSP00000359375	intact:EBI-36065|uniprotkb:D6W4H5|ensemblfungi:YPR174C	psi-mi:fate1_human(display_long)|uniprotkb:Tumor antigen BJ-HCC-2(gene name synonym)|uniprotkb:Cancer/testis antigen 43(gene name synonym)|uniprotkb:FATE1(gene name)|psi-mi:FATE1(display_short)|uniprotkb:FATE(gene name synonym)	psi-mi:yp174_yeast(display_long)|uniprotkb:YPR174C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11535759|imex:IM-24995-1406	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_149076.1|ensembl:ENSG00000147378(gene)|ensembl:ENST00000370350(transcript)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|go:"GO:0051562"(negative regulation of mitochondrial calcium ion concentration)|interpro:IPR039153|interpro:IPR039433|mint:Q969F0|entrezgene/locuslink:89885(identity)	refseq:NP_015500.1|sgd:S000006378|dip:DIP-3800N|ensemblfungi:YPR174C(gene)|ensemblfungi:YPR174C_mRNA(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034399"(nuclear periphery)|interpro:IPR013743(Nap binding NBP1, fungi)|sgd:YPR174C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Nm1N6lO92MHr5rIKC007oouF5RE9606	rogid:R+7auDlEsOm+VR9gJ1jZsF3ST88559292	intact-crc:21FFE19CA24BAEF6|rigid:Lk+btTFjqrWeHn5nH/Yl1jEACt8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q13137	uniprotkb:Q06630	intact:EBI-739580|uniprotkb:B4DDC4|uniprotkb:E7ENK0|uniprotkb:Q53FQ5|uniprotkb:Q53HB5|uniprotkb:Q6IBN9|uniprotkb:Q9BTF7|uniprotkb:B2RBT0|ensembl:ENSP00000258947|uniprotkb:B4E0C0|uniprotkb:E7ETP5|uniprotkb:B4DDT4|uniprotkb:B4DP36|uniprotkb:E9PBE5	intact:EBI-36794|uniprotkb:D6VSS5|ensemblfungi:YDR296W	psi-mi:caco2_human(display_long)|uniprotkb:CALCOCO2(gene name)|psi-mi:CALCOCO2(display_short)|uniprotkb:NDP52(gene name synonym)|uniprotkb:Nuclear domain 10 protein NDP52(gene name synonym)|uniprotkb:Antigen nuclear dot 52 kDa protein(gene name synonym)|uniprotkb:Nuclear dot protein 52(gene name synonym)	psi-mi:mhr1_yeast(display_long)|uniprotkb:MHR1(gene name)|psi-mi:MHR1(display_short)|uniprotkb:YDR296W(locus name)|uniprotkb:Cross-linked transcription component 1(gene name synonym)|uniprotkb:XTC1(gene name synonym)|uniprotkb:Mitochondrial large ribosomal subunit protein mL67(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11535826|imex:IM-24995-1413	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001248319.1|refseq:NP_001248320.1|refseq:NP_001248322.1|refseq:NP_005822.1|ensembl:ENSG00000136436(gene)|ensembl:ENST00000258947(transcript)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016032"(viral process)|go:"GO:0016605"(PML body)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0098792"(xenophagy)|go:"GO:1901098"(positive regulation of autophagosome maturation)|interpro:IPR041611|interpro:IPR041641|mint:Q13137|rcsb pdb:2MXP|rcsb pdb:3VVV|rcsb pdb:3VVW|rcsb pdb:4GXL|rcsb pdb:4HAN|rcsb pdb:4XKL|rcsb pdb:5AAQ|rcsb pdb:5Z7A|rcsb pdb:5Z7L|refseq:NP_001248324.1|dip:DIP-57534N|entrezgene/locuslink:10241(identity)	sgd:S000002704|refseq:NP_010582.3|mint:Q06630|dip:DIP-5727N|ensemblfungi:YDR296W(gene)|ensemblfungi:YDR296W_mRNA(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0000150"(DNA strand exchange activity)|go:"GO:0003677"(DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0006310"(DNA recombination)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0032543"(mitochondrial translation)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0090297"(positive regulation of mitochondrial DNA replication)|interpro:IPR024629|rcsb pdb:3J6B|rcsb pdb:5MRC|rcsb pdb:5MRE|rcsb pdb:5MRF|sgd:YDR296W(identity)	-	crc64:609B121DA1A9DCB8	crc64:F26903A4814091C4	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:N/GPJUGBK+Dh5Cg+csmafphuo9M9606	rogid:eA38S7UNOpP716XSQ0zzhYm2TqA559292	intact-crc:1168D3EE9D8183EB|rigid:Y9bWtIjFM+q05QneRyN40QS46AA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q06630	uniprotkb:O95751	intact:EBI-36794|uniprotkb:D6VSS5|ensemblfungi:YDR296W	intact:EBI-740738|ensembl:ENSP00000359557|uniprotkb:Q6IAR6	psi-mi:mhr1_yeast(display_long)|uniprotkb:MHR1(gene name)|psi-mi:MHR1(display_short)|uniprotkb:YDR296W(locus name)|uniprotkb:Cross-linked transcription component 1(gene name synonym)|uniprotkb:XTC1(gene name synonym)|uniprotkb:Mitochondrial large ribosomal subunit protein mL67(gene name synonym)	psi-mi:ldoc1_human(display_long)|uniprotkb:Leucine zipper protein down-regulated in cancer cells(gene name synonym)|uniprotkb:LDOC1(gene name)|psi-mi:LDOC1(display_short)|uniprotkb:BCUR1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11535817|imex:IM-24995-1412	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002704|refseq:NP_010582.3|mint:Q06630|dip:DIP-5727N|ensemblfungi:YDR296W(gene)|ensemblfungi:YDR296W_mRNA(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0000150"(DNA strand exchange activity)|go:"GO:0003677"(DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0006310"(DNA recombination)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0032543"(mitochondrial translation)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0090297"(positive regulation of mitochondrial DNA replication)|interpro:IPR024629|rcsb pdb:3J6B|rcsb pdb:5MRC|rcsb pdb:5MRE|rcsb pdb:5MRF|sgd:YDR296W(identity)	refseq:NP_036449.1|ensembl:ENSG00000182195(gene)|ensembl:ENST00000370526(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071225"(cellular response to muramyl dipeptide)|interpro:IPR032549|interpro:IPR032567|entrezgene/locuslink:23641(identity)	-	crc64:F26903A4814091C4	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:eA38S7UNOpP716XSQ0zzhYm2TqA559292	rogid:Ediu0oNiZ/+YVY8l3fNdgP5A+v09606	intact-crc:5E2B67D82AC8F9DC|rigid:kvTpwC03DfjelXlTES8y8iAK6q0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O95273	uniprotkb:Q06630	intact:EBI-748961|uniprotkb:A8K3Q0|uniprotkb:A8K3U2|uniprotkb:Q6ZQN9|uniprotkb:Q7Z519|uniprotkb:Q8NBS7|uniprotkb:Q8NBY2|uniprotkb:Q9NS19|uniprotkb:Q9NYH3|uniprotkb:Q9UHX9|ensembl:ENSP00000300213	intact:EBI-36794|uniprotkb:D6VSS5|ensemblfungi:YDR296W	psi-mi:ccdb1_human(display_long)|uniprotkb:Grap2 and cyclin-D-interacting protein(gene name synonym)|uniprotkb:Human homolog of Maid(gene name synonym)|uniprotkb:CCNDBP1(gene name)|psi-mi:CCNDBP1(display_short)|uniprotkb:DIP1(gene name synonym)|uniprotkb:GCIP(gene name synonym)|uniprotkb:HHM(gene name synonym)	psi-mi:mhr1_yeast(display_long)|uniprotkb:MHR1(gene name)|psi-mi:MHR1(display_short)|uniprotkb:YDR296W(locus name)|uniprotkb:Cross-linked transcription component 1(gene name synonym)|uniprotkb:XTC1(gene name synonym)|uniprotkb:Mitochondrial large ribosomal subunit protein mL67(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11535808|imex:IM-24995-1411	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_036274.3|ensembl:ENSG00000166946(gene)|ensembl:ENST00000300213(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0016604"(nuclear body)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR026907|mint:O95273|rcsb pdb:3AY5|entrezgene/locuslink:23582(identity)	sgd:S000002704|refseq:NP_010582.3|mint:Q06630|dip:DIP-5727N|ensemblfungi:YDR296W(gene)|ensemblfungi:YDR296W_mRNA(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0000150"(DNA strand exchange activity)|go:"GO:0003677"(DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0006310"(DNA recombination)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0032543"(mitochondrial translation)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0090297"(positive regulation of mitochondrial DNA replication)|interpro:IPR024629|rcsb pdb:3J6B|rcsb pdb:5MRC|rcsb pdb:5MRE|rcsb pdb:5MRF|sgd:YDR296W(identity)	-	-	crc64:F26903A4814091C4	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Vi9aoFc+Mov6P3X6KGmsTxXqxvM9606	rogid:eA38S7UNOpP716XSQ0zzhYm2TqA559292	intact-crc:B84219867D1417B3|rigid:LtjyODNWPNiD5flamYEvq88v7kM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O43586	uniprotkb:Q06630	intact:EBI-1050964|uniprotkb:O43585|uniprotkb:O95657|uniprotkb:B5BUK4|uniprotkb:B5BU74|ensembl:ENSP00000452746	intact:EBI-36794|uniprotkb:D6VSS5|ensemblfungi:YDR296W	psi-mi:ppip1_human(display_long)|uniprotkb:CD2-binding protein 1(gene name synonym)|uniprotkb:H-PIP(gene name synonym)|uniprotkb:PSTPIP1(gene name)|psi-mi:PSTPIP1(display_short)|uniprotkb:CD2BP1(gene name synonym)	psi-mi:mhr1_yeast(display_long)|uniprotkb:MHR1(gene name)|psi-mi:MHR1(display_short)|uniprotkb:YDR296W(locus name)|uniprotkb:Cross-linked transcription component 1(gene name synonym)|uniprotkb:XTC1(gene name synonym)|uniprotkb:Mitochondrial large ribosomal subunit protein mL67(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11535799|imex:IM-24995-1410	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003969.2|refseq:NP_001308064.1|refseq:NP_001308066.1|ensembl:ENSG00000140368(gene)|ensembl:ENST00000558012(transcript)|go:"GO:0001931"(uropod)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0006954"(inflammatory response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0032154"(cleavage furrow)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051015"(actin filament binding)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR027267|interpro:IPR030777|interpro:IPR031160|interpro:IPR036028|mint:O43586|rcsb pdb:2DIL|reactome:R-HSA-844456|reactome:R-HSA-9660826|entrezgene/locuslink:9051(identity)	sgd:S000002704|refseq:NP_010582.3|mint:Q06630|dip:DIP-5727N|ensemblfungi:YDR296W(gene)|ensemblfungi:YDR296W_mRNA(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0000150"(DNA strand exchange activity)|go:"GO:0003677"(DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0006310"(DNA recombination)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0032543"(mitochondrial translation)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0090297"(positive regulation of mitochondrial DNA replication)|interpro:IPR024629|rcsb pdb:3J6B|rcsb pdb:5MRC|rcsb pdb:5MRE|rcsb pdb:5MRF|sgd:YDR296W(identity)	-	-	crc64:F26903A4814091C4	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:JWK4dCYdcVF6mKwe+hoOri1wwps9606	rogid:eA38S7UNOpP716XSQ0zzhYm2TqA559292	intact-crc:A826CCE6304E2B63|rigid:AWoM5SLQmf4iBA6nWh7+UiNOxcU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q06630	uniprotkb:Q9UJV3-2	intact:EBI-36794|uniprotkb:D6VSS5|ensemblfungi:YDR296W	intact:EBI-10172526|ensembl:ENSP00000413976	psi-mi:mhr1_yeast(display_long)|uniprotkb:MHR1(gene name)|psi-mi:MHR1(display_short)|uniprotkb:YDR296W(locus name)|uniprotkb:Cross-linked transcription component 1(gene name synonym)|uniprotkb:XTC1(gene name synonym)|uniprotkb:Mitochondrial large ribosomal subunit protein mL67(gene name synonym)	psi-mi:q9ujv3-2(display_long)|uniprotkb:RING-type E3 ubiquitin transferase MID2(gene name synonym)|uniprotkb:FXY2(gene name synonym)|uniprotkb:Midin-2(gene name synonym)|uniprotkb:Midline defect 2(gene name synonym)|uniprotkb:Midline-2(gene name synonym)|uniprotkb:RING finger protein 60(gene name synonym)|uniprotkb:RNF60(gene name synonym)|uniprotkb:TRIM1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 1(gene name synonym)|uniprotkb:MID2(gene name)|psi-mi:MID2(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11535853|imex:IM-24995-1416	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002704|refseq:NP_010582.3|mint:Q06630|dip:DIP-5727N|ensemblfungi:YDR296W(gene)|ensemblfungi:YDR296W_mRNA(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0000150"(DNA strand exchange activity)|go:"GO:0003677"(DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0006310"(DNA recombination)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0032543"(mitochondrial translation)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0090297"(positive regulation of mitochondrial DNA replication)|interpro:IPR024629|rcsb pdb:3J6B|rcsb pdb:5MRC|rcsb pdb:5MRE|rcsb pdb:5MRF|sgd:YDR296W(identity)	intact:EBI-751983(isoform-parent)|uniprotkb:Q9UJV3-2(isoform-parent)|ensembl:ENSG00000080561(gene)|ensembl:ENST00000443968(transcript)|entrezgene/locuslink:11043(identity)	-	crc64:F26903A4814091C4	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:eA38S7UNOpP716XSQ0zzhYm2TqA559292	rogid:/FJ+V2H7SaWon7caUWkEkmHFVxQ9606	intact-crc:05E76F0C2B5A3F93|rigid:uav9RSJq+r8k5yH7EhWpKx59nQ0	false	-	sufficient binding region:21-705	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q92997	uniprotkb:Q06630	intact:EBI-739789|uniprotkb:O14642|uniprotkb:Q13531|uniprotkb:Q8N5E9|uniprotkb:Q92607|uniprotkb:D3DNT0|intact:EBI-11081380|uniprotkb:B4E3E5|ensembl:ENSP00000316054	intact:EBI-36794|uniprotkb:D6VSS5|ensemblfungi:YDR296W	psi-mi:dvl3_human(display_long)|uniprotkb:DVL3(gene name)|psi-mi:DVL3(display_short)|uniprotkb:KIAA0208(gene name synonym)|uniprotkb:DSH homolog 3(gene name synonym)	psi-mi:mhr1_yeast(display_long)|uniprotkb:MHR1(gene name)|psi-mi:MHR1(display_short)|uniprotkb:YDR296W(locus name)|uniprotkb:Cross-linked transcription component 1(gene name synonym)|uniprotkb:XTC1(gene name synonym)|uniprotkb:Mitochondrial large ribosomal subunit protein mL67(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11535844|imex:IM-24995-1415	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004414.3|dip:DIP-34509N|ensembl:ENSG00000161202(gene)|ensembl:ENST00000313143(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002020"(protease binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005109"(frizzled binding)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0038031"(non-canonical Wnt signaling pathway via JNK cascade)|go:"GO:0042493"|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050821"(protein stabilization)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0150012"(positive regulation of neuron projection arborization)|go:"GO:1903827"|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008342(Dishevelled-3 protein, C-terminal)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:Q92997|rcsb pdb:6V7O|rcsb pdb:6ZC6|rcsb pdb:6ZC8|reactome:R-HSA-201681|reactome:R-HSA-201688|reactome:R-HSA-4086400|reactome:R-HSA-4641258|reactome:R-HSA-4641262|reactome:R-HSA-5368598|reactome:R-HSA-5663220|reactome:R-HSA-9673324|entrezgene/locuslink:1857(identity)	sgd:S000002704|refseq:NP_010582.3|mint:Q06630|dip:DIP-5727N|ensemblfungi:YDR296W(gene)|ensemblfungi:YDR296W_mRNA(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0000150"(DNA strand exchange activity)|go:"GO:0003677"(DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0006310"(DNA recombination)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0032543"(mitochondrial translation)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0090297"(positive regulation of mitochondrial DNA replication)|interpro:IPR024629|rcsb pdb:3J6B|rcsb pdb:5MRC|rcsb pdb:5MRE|rcsb pdb:5MRF|sgd:YDR296W(identity)	-	-	crc64:F26903A4814091C4	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:yJ3YIp5IhvKTQwa3bK5yTjNyqXk9606	rogid:eA38S7UNOpP716XSQ0zzhYm2TqA559292	intact-crc:E53F61651E768085|rigid:VeX5lQL9qHsDTykQ7ACrwGxW3y0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q06630	uniprotkb:Q5JR59-3	intact:EBI-36794|uniprotkb:D6VSS5|ensemblfungi:YDR296W	intact:EBI-11522433|ensembl:ENSP00000370186	psi-mi:mhr1_yeast(display_long)|uniprotkb:MHR1(gene name)|psi-mi:MHR1(display_short)|uniprotkb:YDR296W(locus name)|uniprotkb:Cross-linked transcription component 1(gene name synonym)|uniprotkb:XTC1(gene name synonym)|uniprotkb:Mitochondrial large ribosomal subunit protein mL67(gene name synonym)	psi-mi:q5jr59-3(display_long)|uniprotkb:MTUS2(gene name)|psi-mi:MTUS2(display_short)|uniprotkb:CAZIP(gene name synonym)|uniprotkb:Cardiac zipper protein(gene name synonym)|uniprotkb:KIAA0774(gene name synonym)|uniprotkb:Microtubule plus-end tracking protein TIP150(gene name synonym)|uniprotkb:TIP150(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11535835|imex:IM-24995-1414	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002704|refseq:NP_010582.3|mint:Q06630|dip:DIP-5727N|ensemblfungi:YDR296W(gene)|ensemblfungi:YDR296W_mRNA(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0000150"(DNA strand exchange activity)|go:"GO:0003677"(DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0006310"(DNA recombination)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0032543"(mitochondrial translation)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0090297"(positive regulation of mitochondrial DNA replication)|interpro:IPR024629|rcsb pdb:3J6B|rcsb pdb:5MRC|rcsb pdb:5MRE|rcsb pdb:5MRF|sgd:YDR296W(identity)	ensembl:ENSG00000132938(gene)|ensembl:ENST00000380808(transcript)|intact:EBI-742948(isoform-parent)|uniprotkb:Q5JR59-3(isoform-parent)|entrezgene/locuslink:23281(identity)	-	crc64:F26903A4814091C4	isoform-comment:No experimental confirmation available.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:eA38S7UNOpP716XSQ0zzhYm2TqA559292	rogid:npId9tC7VoLN/jteoBiRbSYChPs9606	intact-crc:3A646A187BB4AA84|rigid:FVW3iio5D5kaMySpXHM8SU1Py1A	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q06676	uniprotkb:Q15437	intact:EBI-30298|uniprotkb:D6VSV0|ensemblfungi:YDR319C	intact:EBI-742673|uniprotkb:Q5W183|uniprotkb:Q9BS15|uniprotkb:Q9BSI2|uniprotkb:Q9H1D7|intact:EBI-1048165|uniprotkb:Q503A9|uniprotkb:D3DW33|ensembl:ENSP00000262544|ensembl:ENSP00000338844|ensembl:ENSP00000366685|ensembl:ENSP00000497473	psi-mi:yft2_yeast(display_long)|uniprotkb:YFT2(gene name)|psi-mi:YFT2(display_short)|uniprotkb:FIT2A(gene name synonym)|uniprotkb:YDR319C(locus name)|uniprotkb:FIT family protein YFT2(gene name synonym)	psi-mi:sc23b_human(display_long)|uniprotkb:SEC23-related protein B(gene name synonym)|uniprotkb:SEC23B(gene name)|psi-mi:SEC23B(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11535882|imex:IM-24995-1419	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010605.1|sgd:S000002727|dip:DIP-4731N|reactome:R-SCE-8964572|ensemblfungi:YDR319C(gene)|ensemblfungi:YDR319C_mRNA(transcript)|go:"GO:0005773"(vacuole)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0008654"(phospholipid biosynthetic process)|go:"GO:0016818"(hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides)|go:"GO:0019915"(lipid storage)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0034389"(lipid droplet organization)|go:"GO:0140042"(lipid droplet formation)|go:"GO:1900480"(regulation of diacylglycerol biosynthetic process)|go:"GO:1900481"(negative regulation of diacylglycerol biosynthetic process)|interpro:IPR019388|sgd:YDR319C(identity)	refseq:NP_001166216.1|refseq:NP_006354.2|refseq:NP_116780.1|refseq:NP_116781.1|ensembl:ENSG00000101310(gene)|ensembl:ENST00000262544(transcript)|ensembl:ENST00000336714(transcript)|ensembl:ENST00000377465(transcript)|ensembl:ENST00000650089(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008270"(zinc ion binding)|go:"GO:0012505"(endomembrane system)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0090110"(COPII-coated vesicle cargo loading)|go:"GO:0070971"(endoplasmic reticulum exit site)|interpro:IPR006895(Zinc finger, Sec23/Sec24-type)|interpro:IPR006896(Sec23/Sec24 trunk region)|interpro:IPR006900(Sec23/Sec24 helical region)|interpro:IPR007123(Gelsolin region)|interpro:IPR012990(Sec23/Sec24 beta-sandwich)|interpro:IPR029006|interpro:IPR036174|interpro:IPR036175|interpro:IPR036180|interpro:IPR036465|interpro:IPR037364|interpro:IPR037550|mint:Q15437|refseq:XP_016883082.1|entrezgene/locuslink:10483(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:gy1kXEPAQZisfcLxF3V95W1JR60559292	rogid:+3KZ/1jjziSgJRcr81Axquofkl49606	intact-crc:D1F026762923C213|rigid:aA65udexRxRSI7Ii6EO8Hq/9uCE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q06671	uniprotkb:Q13422-7	intact:EBI-3685534|uniprotkb:D6VZ66|ensemblfungi:YLR431C	intact:EBI-11522367|ensembl:ENSP00000352123|ensembl:ENSP00000413025	psi-mi:atg23_yeast(display_long)|uniprotkb:ATG23(gene name)|psi-mi:ATG23(display_short)|uniprotkb:CVT23(gene name synonym)|uniprotkb:Cytoplasm to vacuole targeting protein 23(gene name synonym)|uniprotkb:YLR431C(locus name)	psi-mi:q13422-7(display_long)|uniprotkb:IKZF1(gene name)|psi-mi:IKZF1(display_short)|uniprotkb:IK1(gene name synonym)|uniprotkb:IKAROS(gene name synonym)|uniprotkb:Ikaros family zinc finger protein 1(gene name synonym)|uniprotkb:LYF1(gene name synonym)|uniprotkb:Lymphoid transcription factor LyF-1(gene name synonym)|uniprotkb:ZNFN1A1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11535873|imex:IM-24995-1418	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000004423|refseq:NP_013535.1|ensemblfungi:YLR431C(gene)|ensemblfungi:YLR431C_mRNA(transcript)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0044805"(late nucleophagy)|sgd:YLR431C(identity)	intact:EBI-745305(isoform-parent)|ensembl:ENSG00000185811(gene)|ensembl:ENST00000359197(transcript)|ensembl:ENST00000439701(transcript)|uniprotkb:Q13422-7(isoform-parent)|entrezgene/locuslink:10320(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:6KEtQbyIfmG3hnxsqr3+hHGrEa0559292	rogid:ou/ovXYoMneBNVp4pj38VxenfyY9606	intact-crc:70EFBB90C9DB7A5F|rigid:g+xJ5gDXbhYnOsvVB5FAHzXHfAk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P51116	uniprotkb:Q06667	intact:EBI-740459|uniprotkb:Q8WUM2|uniprotkb:Q86V09|uniprotkb:B2R9M2|uniprotkb:D3DTQ1|ensembl:ENSP00000250113	intact:EBI-33838|uniprotkb:D6VSU4|ensemblfungi:YDR315C	psi-mi:fxr2_human(display_long)|uniprotkb:FXR2(gene name)|psi-mi:FXR2(display_short)|uniprotkb:FMR1L2(gene name synonym)	psi-mi:ipk1_yeast(display_long)|uniprotkb:IPK1(gene name)|psi-mi:IPK1(display_short)|uniprotkb:GSL1(gene name synonym)|uniprotkb:Inositol-1,3,4,5,6-pentakisphosphate 2-kinase(gene name synonym)|uniprotkb:"Ins(1,3,4,5,6)P5 2-kinase"(gene name synonym)|uniprotkb:YDR315C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11535864|imex:IM-24995-1417	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR004087(K Homology)|refseq:NP_004851.2|ensembl:ENSG00000129245(gene)|ensembl:ENST00000250113(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0044326"(dendritic spine neck)|go:"GO:0045182"(translation regulator activity)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0098793"(presynapse)|go:"GO:1902737"(dendritic filopodium)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|interpro:IPR004088(K Homology, type 1)|interpro:IPR008395(Agenet)|interpro:IPR022034|interpro:IPR032172|interpro:IPR036612|interpro:IPR040148|interpro:IPR040472|interpro:IPR041560|mint:P51116|rcsb pdb:3H8Z|entrezgene/locuslink:9513(identity)	sgd:S000002723|reactome:R-SCE-1855167|reactome:R-SCE-1855191|refseq:NP_010601.3|dip:DIP-1388N|ensemblfungi:YDR315C(gene)|ensemblfungi:YDR315C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0032958"(inositol phosphate biosynthetic process)|go:"GO:0035299"(inositol pentakisphosphate 2-kinase activity)|go:"GO:0052746"(inositol phosphorylation)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|interpro:IPR009286(Protein of unknown function DUF941)|sgd:YDR315C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:NnYgyzD2NRGIO1ZHukr5qy44qRE9606	rogid:Fd1kGHt2rvWznhiE9yFCTiLo2oY559292	intact-crc:CD16E5F346F972D3|rigid:8Gufg/KxGSlSinauyqQH63xULZc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q06707	uniprotkb:Q13137	intact:EBI-32671|uniprotkb:D6VZ20|ensemblfungi:YLR385C	intact:EBI-739580|uniprotkb:B4DDC4|uniprotkb:E7ENK0|uniprotkb:Q53FQ5|uniprotkb:Q53HB5|uniprotkb:Q6IBN9|uniprotkb:Q9BTF7|uniprotkb:B2RBT0|ensembl:ENSP00000258947|uniprotkb:B4E0C0|uniprotkb:E7ETP5|uniprotkb:B4DDT4|uniprotkb:B4DP36|uniprotkb:E9PBE5	psi-mi:swc7_yeast(display_long)|uniprotkb:SWC7(gene name)|psi-mi:SWC7(display_short)|uniprotkb:AWS1(gene name synonym)|uniprotkb:YLR385C(locus name)	psi-mi:caco2_human(display_long)|uniprotkb:CALCOCO2(gene name)|psi-mi:CALCOCO2(display_short)|uniprotkb:NDP52(gene name synonym)|uniprotkb:Nuclear domain 10 protein NDP52(gene name synonym)|uniprotkb:Antigen nuclear dot 52 kDa protein(gene name synonym)|uniprotkb:Nuclear dot protein 52(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11535920|imex:IM-24995-1423	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013489.1|sgd:S000004377|dip:DIP-4645N|mint:Q06707|ensemblfungi:YLR385C(gene)|ensemblfungi:YLR385C_mRNA(transcript)|go:"GO:0000812"(Swr1 complex)|go:"GO:0005634"(nucleus)|go:"GO:0006338"(chromatin remodeling)|interpro:IPR020195|sgd:YLR385C(identity)	refseq:NP_001248319.1|refseq:NP_001248320.1|refseq:NP_001248322.1|refseq:NP_005822.1|ensembl:ENSG00000136436(gene)|ensembl:ENST00000258947(transcript)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016032"(viral process)|go:"GO:0016605"(PML body)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0098792"(xenophagy)|go:"GO:1901098"(positive regulation of autophagosome maturation)|interpro:IPR041611|interpro:IPR041641|mint:Q13137|rcsb pdb:2MXP|rcsb pdb:3VVV|rcsb pdb:3VVW|rcsb pdb:4GXL|rcsb pdb:4HAN|rcsb pdb:4XKL|rcsb pdb:5AAQ|rcsb pdb:5Z7A|rcsb pdb:5Z7L|refseq:NP_001248324.1|dip:DIP-57534N|entrezgene/locuslink:10241(identity)	-	crc64:92CCE2FF3DCE72F1	crc64:609B121DA1A9DCB8	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:7DWWay9S3JHtIRpmJHyHeELBg5M559292	rogid:N/GPJUGBK+Dh5Cg+csmafphuo9M9606	intact-crc:B6A50216B019AE84|rigid:EY1ZjaIkZK52NNMpTnv/YZWpAdU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q06707	uniprotkb:P37198	intact:EBI-32671|uniprotkb:D6VZ20|ensemblfungi:YLR385C	intact:EBI-347978|intact:EBI-28983799|ensembl:ENSP00000305503|ensembl:ENSP00000407331|ensembl:ENSP00000471191|ensembl:ENSP00000473192|uniprotkb:Q6GTM2|uniprotkb:Q503A4|uniprotkb:Q96C43|uniprotkb:Q9NSL1|uniprotkb:B3KWU5	psi-mi:swc7_yeast(display_long)|uniprotkb:SWC7(gene name)|psi-mi:SWC7(display_short)|uniprotkb:AWS1(gene name synonym)|uniprotkb:YLR385C(locus name)	psi-mi:nup62_human(display_long)|uniprotkb:NUP62(gene name)|psi-mi:NUP62(display_short)|uniprotkb:62 kDa nucleoporin(gene name synonym)|uniprotkb:Nucleoporin Nup62(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11535911|imex:IM-24995-1422	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013489.1|sgd:S000004377|dip:DIP-4645N|mint:Q06707|ensemblfungi:YLR385C(gene)|ensemblfungi:YLR385C_mRNA(transcript)|go:"GO:0000812"(Swr1 complex)|go:"GO:0005634"(nucleus)|go:"GO:0006338"(chromatin remodeling)|interpro:IPR020195|sgd:YLR385C(identity)	refseq:NP_714941.1|ensembl:ENSG00000213024(gene)|ensembl:ENST00000352066(transcript)|ensembl:ENST00000422090(transcript)|ensembl:ENST00000596217(transcript)|ensembl:ENST00000597029(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005642"(annulate lamellae)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007100"(mitotic centrosome separation)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007569"(cell aging)|go:"GO:0008219"(cell death)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0003682"(chromatin binding)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0019894"(kinesin binding)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042306"(regulation of protein import into nucleus)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043069"(negative regulation of programmed cell death)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045742"(positive regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046578"(regulation of Ras protein signal transduction)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0046601"(positive regulation of centriole replication)|go:"GO:0051028"(mRNA transport)|go:"GO:0051425"(PTB domain binding)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0072686"(mitotic spindle)|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|go:"GO:0090543"(Flemming body)|go:"GO:0098534"(centriole assembly)|go:"GO:1903438"(positive regulation of mitotic cytokinetic process)|go:"GO:1904781"(positive regulation of protein localization to centrosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR007758(Nucleoporin, Nsp1-like, C-terminal)|interpro:IPR026010|interpro:IPR033072|mint:P37198|rcsb pdb:2H4D|rcsb pdb:5IJN|rcsb pdb:5IJO|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|refseq:NP_714940.1|refseq:NP_001180286.1|refseq:NP_036478.2|refseq:NP_057637.2|ensembl:ENSP00000305503|ensembl:ENSP00000407331|ensembl:ENSP00000471191|ensembl:ENSP00000473192|dip:DIP-29749N|entrezgene/locuslink:23636(identity)	-	crc64:92CCE2FF3DCE72F1	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:7DWWay9S3JHtIRpmJHyHeELBg5M559292	rogid:v7mvKvTtVEnLMwcpUZIcdAzge009606	intact-crc:9612E98D0CB9EFD6|rigid:LmH67keCrwmZ13ODEvS29CWwdkw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q06707	uniprotkb:P19012	intact:EBI-32671|uniprotkb:D6VZ20|ensemblfungi:YLR385C	intact:EBI-739566|uniprotkb:Q53XV8|uniprotkb:Q9BUG4|uniprotkb:B3KQY1|uniprotkb:B3KRA2|uniprotkb:E0CX14|ensembl:ENSP00000254043|ensembl:ENSP00000377546	psi-mi:swc7_yeast(display_long)|uniprotkb:SWC7(gene name)|psi-mi:SWC7(display_short)|uniprotkb:AWS1(gene name synonym)|uniprotkb:YLR385C(locus name)	psi-mi:k1c15_human(display_long)|uniprotkb:KRT15(gene name)|psi-mi:KRT15(display_short)|uniprotkb:KRTB(gene name synonym)|uniprotkb:Cytokeratin-15(gene name synonym)|uniprotkb:Keratin-15(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11535902|imex:IM-24995-1421	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013489.1|sgd:S000004377|dip:DIP-4645N|mint:Q06707|ensemblfungi:YLR385C(gene)|ensemblfungi:YLR385C_mRNA(transcript)|go:"GO:0000812"(Swr1 complex)|go:"GO:0005634"(nucleus)|go:"GO:0006338"(chromatin remodeling)|interpro:IPR020195|sgd:YLR385C(identity)	refseq:NP_002266.2|ensembl:ENSG00000171346(gene)|ensembl:ENST00000254043(transcript)|ensembl:ENST00000393976(transcript)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0008544"(epidermis development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097110"(scaffold protein binding)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR039008|mint:P19012|reactome:R-HSA-6805567|reactome:R-HSA-6809371|entrezgene/locuslink:3866(identity)	-	crc64:92CCE2FF3DCE72F1	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:7DWWay9S3JHtIRpmJHyHeELBg5M559292	rogid:WrZQBYQvrWcfrR5ojWXrXp6spPE9606	intact-crc:4AB2507AE5D5C81F|rigid:T1Rwcy8baI7wPgKD8u8cgVBiNEw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q06678	uniprotkb:Q8IYF3-3	intact:EBI-392|uniprotkb:D6VSV4|ensemblfungi:YDR322W	intact:EBI-11523345|ensembl:ENSP00000363453	psi-mi:rm35_yeast(display_long)|uniprotkb:MRPL35(gene name)|psi-mi:MRPL35(display_short)|uniprotkb:YDR322W(locus name)|uniprotkb:D9798.5(orf name)|uniprotkb:YmL35(gene name synonym)|uniprotkb:Mitochondrial large ribosomal subunit protein mL38(gene name synonym)	psi-mi:q8iyf3-3(display_long)|uniprotkb:TEX11(gene name)|psi-mi:TEX11(display_short)|uniprotkb:Protein ZIP4 homolog(gene name synonym)|uniprotkb:ZIP4(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11535891|imex:IM-24995-1420	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010608.1|sgd:S000002730|ensemblfungi:YDR322W(gene)|ensemblfungi:YDR322W_mRNA(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0030162"(regulation of proteolysis)|go:"GO:0030414"(peptidase inhibitor activity)|go:"GO:0046578"(regulation of Ras protein signal transduction)|interpro:IPR008914(Phosphatidylethanolamine-binding protein PEBP)|interpro:IPR035810|interpro:IPR036610|rcsb pdb:3J6B|rcsb pdb:5MRC|rcsb pdb:5MRE|rcsb pdb:5MRF|dip:DIP-6832N|mint:Q06678|sgd:YDR322W(identity)	ensembl:ENSG00000120498(gene)|ensembl:ENST00000374333(transcript)|intact:EBI-742397(isoform-parent)|uniprotkb:Q8IYF3-3(isoform-parent)|entrezgene/locuslink:56159(identity)	-	crc64:C6A2C973121FF555	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:yeCXJ6cEZO5bkf31Et3mVexib3A559292	rogid:PUAMFmnm5ZV2rnJ1rhm9ZeRCixg9606	intact-crc:D801107F476D9146|rigid:lazbbfxyaIRV1E+N0HRaOp/7iZU	false	-	sufficient binding region:9-925	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9BUT1	uniprotkb:Q06819	intact:EBI-6137689|uniprotkb:A8K295|uniprotkb:B4DUF6|uniprotkb:Q503A0|uniprotkb:Q6IA46|uniprotkb:Q6UWD3|uniprotkb:Q9H8S8|uniprotkb:Q9NRX8|ensembl:ENSP00000296424	intact:EBI-166|ensemblfungi:YPR082C|uniprotkb:D6W484	psi-mi:bdh2_human(display_long)|uniprotkb:SDR15C1(gene name synonym)|uniprotkb:Short chain dehydrogenase/reductase family 15C member 1(gene name synonym)|uniprotkb:UNQ6308/PRO20933(orf name)|uniprotkb:BDH2(gene name)|psi-mi:BDH2(display_short)|uniprotkb:DHRS6(gene name synonym)|uniprotkb:Dehydrogenase/reductase SDR family member 6(gene name synonym)|uniprotkb:Oxidoreductase UCPA(gene name synonym)|uniprotkb:R-beta-hydroxybutyrate dehydrogenase(gene name synonym)	psi-mi:dib1_yeast(display_long)|uniprotkb:DIB1(gene name)|psi-mi:DIB1(display_short)|uniprotkb:CDH1(gene name synonym)|uniprotkb:SNU16(gene name synonym)|uniprotkb:YPR082C(locus name)|uniprotkb:P9513.12(orf name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11535958|imex:IM-24995-1427	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011530430.1|refseq:NP_064524.3|refseq:XP_016863951.1|ensembl:ENSG00000164039(gene)|ensembl:ENST00000296424(transcript)|go:"GO:0003858"(3-hydroxybutyrate dehydrogenase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0016616"(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|go:"GO:0016628"(oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor)|go:"GO:0019290"(siderophore biosynthetic process)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0042168"(heme metabolic process)|go:"GO:0051287"(NAD binding)|go:"GO:0055072"(iron ion homeostasis)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR020904|interpro:IPR036291|rcsb pdb:2AG5|reactome:R-HSA-77111|entrezgene/locuslink:56898(identity)	refseq:NP_015407.1|sgd:S000006286|ensemblfungi:YPR082C(gene)|ensemblfungi:YPR082C_mRNA(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005682"(U5 snRNP)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|interpro:IPR004123(mRNA splicing factor, thioredoxin-like U5 snRNP)|interpro:IPR036249|rcsb pdb:3JCM|rcsb pdb:5GAN|rcsb pdb:5GAP|rcsb pdb:5NRL|rcsb pdb:5ZWM|rcsb pdb:5ZWO|dip:DIP-1289N|sgd:YPR082C(identity)	-	-	crc64:B8C11278571C57E5	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:jo1enuFW27NpCn5SWMEBipbUKXA9606	rogid:mRibIpinKPlRNdh60VJj/Z0tjUc559292	intact-crc:23551FA3AC0E4235|rigid:PXBSTSrHAtEBVhKdNzJ15cl3Y9w	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8TBB1	uniprotkb:Q06819	intact:EBI-739832|uniprotkb:Q4W5K7|uniprotkb:Q8N4C2|uniprotkb:Q96MJ7|uniprotkb:Q9BY20|ensembl:ENSP00000263925	intact:EBI-166|ensemblfungi:YPR082C|uniprotkb:D6W484	psi-mi:lnx1_human(display_long)|uniprotkb:LNX1(gene name)|psi-mi:LNX1(display_short)|uniprotkb:LNX(gene name synonym)|uniprotkb:Numb-binding protein 1(gene name synonym)|uniprotkb:Ligand of Numb-protein X 1(gene name synonym)|uniprotkb:PDZ domain-containing RING finger protein 2(gene name synonym)|uniprotkb:PDZRN2(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase LNX(gene name synonym)|uniprotkb:UNQ574/PRO1136(orf name)	psi-mi:dib1_yeast(display_long)|uniprotkb:DIB1(gene name)|psi-mi:DIB1(display_short)|uniprotkb:CDH1(gene name synonym)|uniprotkb:SNU16(gene name synonym)|uniprotkb:YPR082C(locus name)|uniprotkb:P9513.12(orf name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11535949|imex:IM-24995-1426	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001119800.1|refseq:NP_116011.2|refseq:XP_005265842.1|refseq:XP_016864265.1|ensembl:ENSG00000072201(gene)|ensembl:ENST00000263925(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR036034|mint:Q8TBB1|rcsb pdb:3B76|rcsb pdb:5H7R|rcsb pdb:5H7S|reactome:R-HSA-983168|entrezgene/locuslink:84708(identity)	refseq:NP_015407.1|sgd:S000006286|ensemblfungi:YPR082C(gene)|ensemblfungi:YPR082C_mRNA(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005682"(U5 snRNP)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|interpro:IPR004123(mRNA splicing factor, thioredoxin-like U5 snRNP)|interpro:IPR036249|rcsb pdb:3JCM|rcsb pdb:5GAN|rcsb pdb:5GAP|rcsb pdb:5NRL|rcsb pdb:5ZWM|rcsb pdb:5ZWO|dip:DIP-1289N|sgd:YPR082C(identity)	-	-	crc64:B8C11278571C57E5	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:tWvePnVxh9yxWl8nQd3KZhCSKKo9606	rogid:mRibIpinKPlRNdh60VJj/Z0tjUc559292	intact-crc:BE1B09802D336A39|rigid:Z62+WYYqaD8KbDFQTEubq/DK/Pg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8IYA8	uniprotkb:Q06819	intact:EBI-8638439|intact:EBI-28969497|ensembl:ENSP00000296449|ensembl:ENSP00000391788|ensembl:ENSP00000407837|uniprotkb:C9JJL0|uniprotkb:Q96LP7|intact:MINT-8162095|uniprotkb:Q05DG9	intact:EBI-166|ensemblfungi:YPR082C|uniprotkb:D6W484	psi-mi:iho1_human(display_long)|uniprotkb:IHO1(gene name)|psi-mi:IHO1(display_short)|uniprotkb:CCDC36(gene name synonym)|uniprotkb:Cancer/testis antigen 74(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 36(gene name synonym)	psi-mi:dib1_yeast(display_long)|uniprotkb:DIB1(gene name)|psi-mi:DIB1(display_short)|uniprotkb:CDH1(gene name synonym)|uniprotkb:SNU16(gene name synonym)|uniprotkb:YPR082C(locus name)|uniprotkb:P9513.12(orf name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11535938|imex:IM-24995-1425	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000296449|ensembl:ENST00000366429|ensembl:ENSP00000403700|ensembl:ENSP00000391788|ensembl:ENSP00000407837|ensembl:ENSG00000173421(gene)|ensembl:ENST00000296449(transcript)|ensembl:ENST00000438782(transcript)|ensembl:ENST00000452691(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0006310"(DNA recombination)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0042138"(meiotic DNA double-strand break formation)|go:"GO:0048477"(oogenesis)|go:"GO:0060629"(regulation of homologous chromosome segregation)|interpro:IPR031529|mint:Q8IYA8|refseq:XP_011531974.1|refseq:XP_011531975.1|refseq:NP_001128669.1|refseq:NP_835467.2|refseq:XP_006713187.1|entrezgene/locuslink:339834(identity)	refseq:NP_015407.1|sgd:S000006286|ensemblfungi:YPR082C(gene)|ensemblfungi:YPR082C_mRNA(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005682"(U5 snRNP)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|interpro:IPR004123(mRNA splicing factor, thioredoxin-like U5 snRNP)|interpro:IPR036249|rcsb pdb:3JCM|rcsb pdb:5GAN|rcsb pdb:5GAP|rcsb pdb:5NRL|rcsb pdb:5ZWM|rcsb pdb:5ZWO|dip:DIP-1289N|sgd:YPR082C(identity)	-	comment:mint	crc64:B8C11278571C57E5	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:+TNQLExkhmC1NWqsE240Cx7zFVU9606	rogid:mRibIpinKPlRNdh60VJj/Z0tjUc559292	intact-crc:B8F5D4B02E9BFDD5|rigid:4GejNbKKpIULMOfZDB67JAlCfpM	false	sufficient binding region:11-594	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q06810	uniprotkb:O43765	intact:EBI-2068557|uniprotkb:D6W479|uniprotkb:Q6B149|ensemblfungi:YPR075C	intact:EBI-347996|ensembl:ENSP00000221566|ensembl:ENSP00000503397|ensembl:ENSP00000504495|uniprotkb:Q9BTZ9|intact:EBI-1045243|uniprotkb:Q6FIA9|uniprotkb:D6W610	psi-mi:opy2_yeast(display_long)|uniprotkb:OPY2(gene name)|psi-mi:OPY2(display_short)|uniprotkb:Overproduction-induced pheromone-resistant protein 2(gene name synonym)|uniprotkb:YPR075C(locus name)	psi-mi:sgta_human(display_long)|uniprotkb:SGTA(gene name)|psi-mi:SGTA(display_short)|uniprotkb:SGT(gene name synonym)|uniprotkb:Alpha-SGT(gene name synonym)|uniprotkb:Vpu-binding protein(gene name synonym)|uniprotkb:SGT1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11535929|imex:IM-24995-1424	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015400.1|sgd:S000006279|interpro:IPR018571|mint:Q06810|ensemblfungi:YPR075C(gene)|ensemblfungi:YPR075C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000751"(mitotic cell cycle G1 arrest in response to pheromone)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007231"(osmosensory signaling pathway)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:1900436"(positive regulation of filamentous growth of a population of unicellular organisms in response to starvation)|sgd:YPR075C(identity)	rcsb pdb:4CPG|rcsb pdb:4GOD|rcsb pdb:4GOE|rcsb pdb:4GOF|reactome:R-HSA-9609523|rcsb pdb:2VYI|ensembl:ENSG00000104969(gene)|ensembl:ENST00000221566(transcript)|ensembl:ENST00000676943(transcript)|ensembl:ENST00000677149(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072380"(TRC complex)|go:"GO:0098850"(extrinsic component of synaptic vesicle membrane)|go:"GO:1903070"(negative regulation of ER-associated ubiquitin-dependent protein catabolic process)|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)|go:"GO:1903646"(positive regulation of chaperone-mediated protein folding)|go:"GO:1904288"(BAT3 complex binding)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR032374|mint:O43765|refseq:XP_011526480.1|refseq:NP_003012.1|entrezgene/locuslink:6449(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:avNmi6o7WtIkxIyUvhoboBXL8sc559292	rogid:r/Cyj4UJk/cS8QdrbjhTZMPCigI9606	intact-crc:84F756309C4B157F|rigid:TCNluPxabzIjedlLFatvZqtighs	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q07379	uniprotkb:Q08379	intact:EBI-2342994|uniprotkb:D6VRT9|ensemblfungi:YDL057W	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	psi-mi:yd057_yeast(display_long)|uniprotkb:YDL057W(locus name)	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11535985|imex:IM-24995-1430	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002215|refseq:NP_010226.1|interpro:IPR022742|interpro:IPR029058|ensemblfungi:YDL057W(gene)|ensemblfungi:YDL057W_mRNA(transcript)|go:"GO:0016020"(membrane)|go:"GO:0016298"(lipase activity)|sgd:YDL057W(identity)	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N|entrezgene/locuslink:2801(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2017/05/26	rogid:U0Sf+t16Ti+vYEOEePrGjlqflhQ559292	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	intact-crc:15E3774EFF3CBDBF|rigid:t/tkMK4SbkVX9DfY0HE+ECrpGW4	false	-	sufficient binding region:383-1002	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q06892	uniprotkb:Q8N9N5-2	intact:EBI-13701|uniprotkb:Q08928|uniprotkb:D6W3I1|ensemblfungi:YPL188W	intact:EBI-11524452|ensembl:ENSP00000347125	psi-mi:pos5_yeast(display_long)|uniprotkb:POS5(gene name)|psi-mi:POS5(display_short)|uniprotkb:YPL188W(locus name)	psi-mi:q8n9n5-2(display_long)|uniprotkb:BANP(gene name)|psi-mi:BANP(display_short)|uniprotkb:BEN domain-containing protein 1(gene name synonym)|uniprotkb:BEND1(gene name synonym)|uniprotkb:Btg3-associated nuclear protein(gene name synonym)|uniprotkb:SMAR1(gene name synonym)|uniprotkb:Scaffold/matrix-associated region-1-binding protein(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11535976|imex:IM-24995-1429	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000006109|refseq:NP_015136.1|ensemblfungi:YPL188W(gene)|ensemblfungi:YPL188W_mRNA(transcript)|go:"GO:0003951"(NAD+ kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006741"(NADP biosynthetic process)|go:"GO:0019674"(NAD metabolic process)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0042736"(NADH kinase activity)|interpro:IPR002504(ATP-NAD/AcoX kinase)|interpro:IPR016064(ATP-NAD kinase, PpnK-type)|interpro:IPR017437(ATP-NAD kinase, PpnK-type, all-beta)|interpro:IPR017438(ATP-NAD kinase, PpnK-type, alpha/beta)|rcsb pdb:3AFO|dip:DIP-5503N|sgd:YPL188W(identity)	ensembl:ENSG00000172530(gene)|ensembl:ENST00000355022(transcript)|intact:EBI-744695(isoform-parent)|uniprotkb:Q8N9N5-2(isoform-parent)|entrezgene/locuslink:54971(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:4n8TcpxeCYBUCHDHMqmxXeNsiGg559292	rogid:ESe6iCAhvq+i57fQHz3rGyg6UOo9606	intact-crc:DC63563AA1FE44CC|rigid:fkIWPJt/JzO5lZHgnnu/7NAaj7s	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q06892	uniprotkb:O95544	intact:EBI-13701|uniprotkb:Q08928|uniprotkb:D6W3I1|ensemblfungi:YPL188W	intact:EBI-743949|uniprotkb:Q9H931|uniprotkb:A8K296|uniprotkb:A6NNN3|uniprotkb:B7Z434|uniprotkb:F5GXR5|uniprotkb:Q5QPS4|uniprotkb:Q9H2P2|ensembl:ENSP00000341679|ensembl:ENSP00000344340	psi-mi:pos5_yeast(display_long)|uniprotkb:POS5(gene name)|psi-mi:POS5(display_short)|uniprotkb:YPL188W(locus name)	psi-mi:nadk_human(display_long)|uniprotkb:"Poly(P)/ATP NAD kinase"(gene name synonym)|uniprotkb:NADK(gene name)|psi-mi:NADK(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11535967|imex:IM-24995-1428	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000006109|refseq:NP_015136.1|ensemblfungi:YPL188W(gene)|ensemblfungi:YPL188W_mRNA(transcript)|go:"GO:0003951"(NAD+ kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006741"(NADP biosynthetic process)|go:"GO:0019674"(NAD metabolic process)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0042736"(NADH kinase activity)|interpro:IPR002504(ATP-NAD/AcoX kinase)|interpro:IPR016064(ATP-NAD kinase, PpnK-type)|interpro:IPR017437(ATP-NAD kinase, PpnK-type, all-beta)|interpro:IPR017438(ATP-NAD kinase, PpnK-type, alpha/beta)|rcsb pdb:3AFO|dip:DIP-5503N|sgd:YPL188W(identity)	refseq:NP_001185922.1|refseq:NP_001185923.1|refseq:NP_001185924.1|refseq:NP_075394.3|refseq:XP_005244835.1|refseq:XP_006710900.1|ensembl:ENSG00000008130(gene)|ensembl:ENST00000341426(transcript)|ensembl:ENST00000341991(transcript)|go:"GO:0003951"(NAD+ kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006741"(NADP biosynthetic process)|go:"GO:0016310"(phosphorylation)|go:"GO:0019674"(NAD metabolic process)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046872"(metal ion binding)|interpro:IPR002504(ATP-NAD/AcoX kinase)|interpro:IPR016064(ATP-NAD kinase, PpnK-type)|interpro:IPR017437(ATP-NAD kinase, PpnK-type, all-beta)|interpro:IPR017438(ATP-NAD kinase, PpnK-type, alpha/beta)|mint:O95544|rcsb pdb:3PFN|reactome:R-HSA-196807|entrezgene/locuslink:65220(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:4n8TcpxeCYBUCHDHMqmxXeNsiGg559292	rogid:XPfRviZiKsV+1JOUi7BsMrIa3M49606	intact-crc:ACA606B37DA5E802|rigid:UBiQvKC4Vp5FyW8BDGGA5N6aQmM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q07379	uniprotkb:Q9Y2D8	intact:EBI-2342994|uniprotkb:D6VRT9|ensemblfungi:YDL057W	intact:EBI-2212028|uniprotkb:B4DFE3|uniprotkb:J3KR02|uniprotkb:A8K8W0|uniprotkb:D3DT13|uniprotkb:Q6P2P8|uniprotkb:Q6ULS1|uniprotkb:Q7L168|uniprotkb:Q9UIX0|intact:EBI-10964529|ensembl:ENSP00000340279	psi-mi:yd057_yeast(display_long)|uniprotkb:YDL057W(locus name)	psi-mi:adip_human(display_long)|uniprotkb:SSX2IP(gene name)|psi-mi:SSX2IP(display_short)|uniprotkb:KIAA0923(gene name synonym)|uniprotkb:Afadin DIL domain-interacting protein(gene name synonym)|uniprotkb:SSX2-interacting protein(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11536024|imex:IM-24995-1434	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002215|refseq:NP_010226.1|interpro:IPR022742|interpro:IPR029058|ensemblfungi:YDL057W(gene)|ensemblfungi:YDL057W_mRNA(transcript)|go:"GO:0016020"(membrane)|go:"GO:0016298"(lipase activity)|sgd:YDL057W(identity)	refseq:XP_011538912.1|refseq:NP_001159765.1|refseq:NP_001159766.1|refseq:NP_001159767.1|refseq:NP_001159889.1|refseq:NP_054740.3|refseq:XP_005270484.1|refseq:XP_005270485.1|refseq:XP_006710394.1|refseq:XP_016855723.1|ensembl:ENSG00000117155(gene)|ensembl:ENST00000342203(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005912"(adherens junction)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031252"(cell leading edge)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0035735"(intraciliary transport involved in cilium assembly)|go:"GO:0036064"(ciliary basal body)|go:"GO:0060271"(cilium assembly)|go:"GO:2000145"(regulation of cell motility)|interpro:IPR021622|mint:Q9Y2D8|entrezgene/locuslink:117178(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:U0Sf+t16Ti+vYEOEePrGjlqflhQ559292	rogid:E0VeMRF9SrpQKSJFP01XEbMjeF89606	intact-crc:A5D2DD9B4F8BEDAA|rigid:LpBusrQr3b/2e4C6qtgDdqgBuNo	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9HCM9-2	uniprotkb:Q07379	intact:EBI-11523450|ensembl:ENSP00000365847|ensembl:ENSP00000373095|ensembl:ENSP00000373097|ensembl:ENSP00000379797|ensembl:ENSP00000379800|ensembl:ENSP00000383486|ensembl:ENSP00000387445|ensembl:ENSP00000389198|ensembl:ENSP00000389852|ensembl:ENSP00000392130|ensembl:ENSP00000394353|ensembl:ENSP00000396986|ensembl:ENSP00000398956|ensembl:ENSP00000401071|ensembl:ENSP00000401184|ensembl:ENSP00000404340|ensembl:ENSP00000404904|ensembl:ENSP00000411582|ensembl:ENSP00000412743|ensembl:ENSP00000414525|ensembl:ENSP00000415259	intact:EBI-2342994|uniprotkb:D6VRT9|ensemblfungi:YDL057W	psi-mi:q9hcm9-2(display_long)|uniprotkb:TRIM39(gene name)|psi-mi:TRIM39(display_short)|uniprotkb:RING finger protein 23(gene name synonym)|uniprotkb:RNF23(gene name synonym)|uniprotkb:TFP(gene name synonym)|uniprotkb:Testis-abundant finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 39(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM39(gene name synonym)|uniprotkb:TIM39beta(isoform synonym)	psi-mi:yd057_yeast(display_long)|uniprotkb:YDL057W(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11536014|imex:IM-24995-1433	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-739510(isoform-parent)|ensembl:ENSG00000204599(gene)|ensembl:ENSG00000206495(gene)|ensembl:ENSG00000224994(gene)|ensembl:ENSG00000226437(gene)|ensembl:ENSG00000229929(gene)|ensembl:ENSG00000230308(gene)|ensembl:ENSG00000232839(gene)|ensembl:ENST00000376659(transcript)|ensembl:ENST00000383601(transcript)|ensembl:ENST00000383603(transcript)|ensembl:ENST00000396548(transcript)|ensembl:ENST00000396551(transcript)|ensembl:ENST00000400644(transcript)|ensembl:ENST00000414015(transcript)|ensembl:ENST00000419790(transcript)|ensembl:ENST00000430502(transcript)|ensembl:ENST00000431272(transcript)|ensembl:ENST00000433900(transcript)|ensembl:ENST00000438076(transcript)|ensembl:ENST00000438859(transcript)|ensembl:ENST00000440117(transcript)|ensembl:ENST00000443109(transcript)|ensembl:ENST00000446397(transcript)|ensembl:ENST00000449318(transcript)|ensembl:ENST00000450778(transcript)|ensembl:ENST00000451132(transcript)|ensembl:ENST00000452705(transcript)|ensembl:ENST00000458607(transcript)|uniprotkb:Q9HCM9-2(isoform-parent)|entrezgene/locuslink:56658(identity)	sgd:S000002215|refseq:NP_010226.1|interpro:IPR022742|interpro:IPR029058|ensemblfungi:YDL057W(gene)|ensemblfungi:YDL057W_mRNA(transcript)|go:"GO:0016020"(membrane)|go:"GO:0016298"(lipase activity)|sgd:YDL057W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:UfSn2+IVRxtGomVeDGdZpL7mz5I9606	rogid:U0Sf+t16Ti+vYEOEePrGjlqflhQ559292	intact-crc:61905DF8B7A681F2|rigid:LujSrb70dn9603zLaNySPeB9lTQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8TAP6	uniprotkb:Q07379	intact:EBI-742887|ensembl:ENSP00000262127|uniprotkb:Q658N5|uniprotkb:Q9H9U7|uniprotkb:B0YJB2|uniprotkb:B4DXG5|uniprotkb:B4DZW1	intact:EBI-2342994|uniprotkb:D6VRT9|ensemblfungi:YDL057W	psi-mi:cep76_human(display_long)|uniprotkb:CEP76(gene name)|psi-mi:CEP76(display_short)|uniprotkb:C18orf9(gene name synonym)	psi-mi:yd057_yeast(display_long)|uniprotkb:YDL057W(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11536005|imex:IM-24995-1432	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_079175.2|ensembl:ENSG00000101624(gene)|ensembl:ENST00000262127(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0046599"(regulation of centriole replication)|interpro:IPR028926|interpro:IPR038765|mint:Q8TAP6|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_001258918.1|entrezgene/locuslink:79959(identity)	sgd:S000002215|refseq:NP_010226.1|interpro:IPR022742|interpro:IPR029058|ensemblfungi:YDL057W(gene)|ensemblfungi:YDL057W_mRNA(transcript)|go:"GO:0016020"(membrane)|go:"GO:0016298"(lipase activity)|sgd:YDL057W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:fWzb8oIU35oVWomyDrf8u5sbxUk9606	rogid:U0Sf+t16Ti+vYEOEePrGjlqflhQ559292	intact-crc:D0781147F3FE2C82|rigid:aenOWHEG1ZfDrZNsCYxMcOs3fd4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P35520	uniprotkb:Q07379	intact:EBI-740135|uniprotkb:Q99425|uniprotkb:Q9BWC5|uniprotkb:B2R993|uniprotkb:D3DSK4|intact:EBI-14245939|ensembl:ENSP00000344460|ensembl:ENSP00000352643|ensembl:ENSP00000381225|ensembl:ENSP00000381231	intact:EBI-2342994|uniprotkb:D6VRT9|ensemblfungi:YDL057W	psi-mi:cbs_human(display_long)|uniprotkb:CBS(gene name)|psi-mi:CBS(display_short)|uniprotkb:Serine sulfhydrase(gene name synonym)|uniprotkb:Beta-thionase(gene name synonym)	psi-mi:yd057_yeast(display_long)|uniprotkb:YDL057W(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11535996|imex:IM-24995-1431	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000062.1|refseq:NP_001171479.1|refseq:NP_001171480.1|ensembl:ENSG00000160200(gene)|ensembl:ENST00000352178(transcript)|ensembl:ENST00000359624(transcript)|ensembl:ENST00000398158(transcript)|go:"GO:0004122"(cystathionine beta-synthase activity)|ensembl:ENST00000398165(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006535"(cysteine biosynthetic process from serine)|go:"GO:0006563"(L-serine metabolic process)|go:"GO:0006565"(L-serine catabolic process)|go:"GO:0019343"(cysteine biosynthetic process via cystathionine)|go:"GO:0019344"(cysteine biosynthetic process)|go:"GO:0019346"(transsulfuration)|go:"GO:0019448"(L-cysteine catabolic process)|go:"GO:0019825"(oxygen binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0020037"(heme binding)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042262"(DNA protection)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043418"(homocysteine catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0050421"("nitrite reductase (NO-forming) activity")|go:"GO:0050667"(homocysteine metabolic process)|go:"GO:0070025"(carbon monoxide binding)|go:"GO:0070026"(nitric oxide binding)|go:"GO:0070814"(hydrogen sulfide biosynthetic process)|go:"GO:0072341"(modified amino acid binding)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR001216(Cysteine synthase/cystathionine beta-synthase P-phosphate-binding site)|interpro:IPR001926(Pyridoxal phosphate-dependent enzyme, beta subunit)|interpro:IPR005857(Cystathionine beta-synthase)|interpro:IPR036052|mint:P35520|rcsb pdb:1JBQ|rcsb pdb:1M54|rcsb pdb:4COO|rcsb pdb:4L0D|rcsb pdb:4L27|rcsb pdb:4L28|rcsb pdb:4L3V|rcsb pdb:4PCU|rcsb pdb:4UUU|rcsb pdb:5MMS|reactome:R-HSA-1614603|reactome:R-HSA-2408508|refseq:XP_011528079.1|refseq:XP_011528083.1|refseq:XP_011528084.1|refseq:XP_011544396.1|refseq:XP_011544397.1|refseq:XP_011544399.1|refseq:XP_011544400.1|refseq:XP_011544401.1|refseq:NP_001307227.1|refseq:NP_001308002.1|refseq:XP_016883700.1|refseq:XP_016883701.1|refseq:XP_016883702.1|refseq:XP_016883703.1|refseq:XP_016883704.1|refseq:XP_016883705.1|refseq:XP_016883706.1|refseq:XP_016883707.1|refseq:XP_016883978.1|refseq:XP_016883979.1|refseq:XP_016883980.1|refseq:XP_016883981.1|entrezgene/locuslink:875(identity)	sgd:S000002215|refseq:NP_010226.1|interpro:IPR022742|interpro:IPR029058|ensemblfungi:YDL057W(gene)|ensemblfungi:YDL057W_mRNA(transcript)|go:"GO:0016020"(membrane)|go:"GO:0016298"(lipase activity)|sgd:YDL057W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:f9eo0cPOHppVY7Nqejag3YyK18s9606	rogid:U0Sf+t16Ti+vYEOEePrGjlqflhQ559292	intact-crc:41B5B6CFA556DDC2|rigid:T9PY+yIXzgaFi35EqGJeQoGF1As	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q07379	uniprotkb:Q9Y2J4	intact:EBI-2342994|uniprotkb:D6VRT9|ensemblfungi:YDL057W	intact:EBI-746752|intact:EBI-28986657|ensembl:ENSP00000409999|uniprotkb:Q53EP1|uniprotkb:Q96F99|uniprotkb:Q9UKB4|uniprotkb:A8K6F1|uniprotkb:B7Z5Q1|uniprotkb:E9PHW3	psi-mi:yd057_yeast(display_long)|uniprotkb:YDL057W(locus name)	psi-mi:amol2_human(display_long)|uniprotkb:Leman coiled-coil protein(gene name synonym)|uniprotkb:AMOTL2(gene name)|psi-mi:AMOTL2(display_short)|uniprotkb:KIAA0989(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11536033|imex:IM-24995-1435	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002215|refseq:NP_010226.1|interpro:IPR022742|interpro:IPR029058|ensemblfungi:YDL057W(gene)|ensemblfungi:YDL057W_mRNA(transcript)|go:"GO:0016020"(membrane)|go:"GO:0016298"(lipase activity)|sgd:YDL057W(identity)	refseq:NP_001265612.1|refseq:NP_001265614.1|ensembl:ENSG00000114019(gene)|refseq:XP_006713717.1|refseq:NP_057285.3|refseq:XP_011511183.1|ensembl:ENST00000422605(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0003365"(establishment of cell polarity involved in ameboidal cell migration)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0035329"(hippo signaling)|go:"GO:0055037"(recycling endosome)|interpro:IPR009114(Angiomotin)|interpro:IPR024646|mint:Q9Y2J4|reactome:R-HSA-2028269|refseq:XP_016862069.1|refseq:XP_016862070.1|refseq:XP_016862071.1|ensembl:ENST00000249883|ensembl:ENSP00000249883|ensembl:ENSP00000409999|ensembl:ENST00000513145|ensembl:ENSP00000425475|ensembl:ENST00000514516|ensembl:ENSP00000424765|dip:DIP-57510N|entrezgene/locuslink:51421(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:U0Sf+t16Ti+vYEOEePrGjlqflhQ559292	rogid:SHtKAcLLnTpSSLwVE7yQ1WECoZk9606	intact-crc:A77E15BEB886B873|rigid:lshhUmMY13Dj00iSsAILwXja8W8	false	-	sufficient binding region:314-779	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q07540	uniprotkb:Q92609	intact:EBI-2206814|uniprotkb:D6VRN0|ensemblfungi:YDL120W	intact:EBI-742381|uniprotkb:A6NP25|intact:EBI-28978959|ensembl:ENSP00000253692|ensembl:ENSP00000398127|uniprotkb:C9JP52	psi-mi:frda_yeast(display_long)|uniprotkb:YFH1(gene name)|psi-mi:YFH1(display_short)|uniprotkb:YDL120W(locus name)	psi-mi:tbcd5_human(display_long)|uniprotkb:TBC1D5(gene name)|psi-mi:TBC1D5(display_short)|uniprotkb:KIAA0210(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11536053|imex:IM-24995-1437	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-7485N|refseq:NP_010163.1|sgd:S000002278|mint:Q07540|ensemblfungi:YDL120W(gene)|ensemblfungi:YDL120W_mRNA(transcript)|go:"GO:0004322"(ferroxidase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006121"(mitochondrial electron transport, succinate to ubiquinone)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0006783"(heme biosynthetic process)|go:"GO:0006811"(ion transport)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008199"(ferric iron binding)|go:"GO:0010040"("response to iron(II) ion")|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0018283"(iron incorporation into metallo-sulfur cluster)|go:"GO:0034986"(iron chaperone activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|interpro:IPR002908(Frataxin-like)|interpro:IPR017789(Frataxin)|interpro:IPR020895|interpro:IPR036524|rcsb pdb:2FQL|rcsb pdb:2GA5|rcsb pdb:3OEQ|rcsb pdb:3OER|rcsb pdb:4EC2|rcsb pdb:5T0V|rcsb pdb:5TRE|reactome:R-SCE-1268020|reactome:R-SCE-1362409|go:"GO:0008198"(ferrous iron binding)|sgd:YDL120W(identity)	ensembl:ENSP00000253692|ensembl:ENSP00000398127|ensembl:ENSP00000402935|ensembl:ENST00000446818|refseq:NP_055559.1|refseq:XP_011532586.1|refseq:XP_011532583.1|refseq:XP_011532585.1|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005776"(autophagosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006914"(autophagy)|go:"GO:0010008"(endosome membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0030904"(retromer complex)|go:"GO:0035612"(AP-2 adaptor complex binding)|ensembl:ENSG00000131374(gene)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042594"(response to starvation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:1905394"(retromer complex binding)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR035969|mint:Q92609|rcsb pdb:5GTU|ensembl:ENST00000253692(transcript)|ensembl:ENST00000429383(transcript)|go:"GO:0002092"(positive regulation of receptor internalization)|refseq:NP_001127853.1|refseq:XP_006713493.1|refseq:XP_016863041.1|refseq:XP_016863042.1|refseq:XP_016863043.1|refseq:XP_016863044.1|refseq:XP_016863045.1|refseq:XP_016863046.1|entrezgene/locuslink:9779(identity)	-	crc64:AB1FF7478EF0E5D6	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:4UcroTodEXb/5+xHGpnXDXf/rd8559292	rogid:GZ7WP4suMiSPSAJK0TZWQMQZxzU9606	intact-crc:AB553B817C1CB4E5|rigid:ygkxYyPIYj4peP+w7qkAkVu9sz0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:A0A024R0Y4	uniprotkb:Q07540	intact:EBI-11523730|ensembl:ENSP00000477709|ensembl:ENSP00000478363|ensembl:ENSP00000481091	intact:EBI-2206814|uniprotkb:D6VRN0|ensemblfungi:YDL120W	psi-mi:a0a024r0y4_human(display_long)|uniprotkb:TADA2A(gene name)|psi-mi:TADA2A(display_short)|uniprotkb:TADA2L(gene name synonym)|uniprotkb:hCG_28187(orf name)	psi-mi:frda_yeast(display_long)|uniprotkb:YFH1(gene name)|psi-mi:YFH1(display_short)|uniprotkb:YDL120W(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11536044|imex:IM-24995-1436	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001159577.2|refseq:NP_001479.4|ensembl:ENSG00000276234(gene)|ensembl:ENST00000612272(transcript)|ensembl:ENST00000615182(transcript)|ensembl:ENST00000620628(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031063"(regulation of histone deacetylation)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0035065"(regulation of histone acetylation)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090043"(regulation of tubulin deacetylation)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016827(Transcriptional adaptor 2)|interpro:IPR017884|interpro:IPR017930|interpro:IPR036388|interpro:IPR041983|interpro:IPR043145|entrezgene/locuslink:6871(identity)	dip:DIP-7485N|refseq:NP_010163.1|sgd:S000002278|mint:Q07540|ensemblfungi:YDL120W(gene)|ensemblfungi:YDL120W_mRNA(transcript)|go:"GO:0004322"(ferroxidase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006121"(mitochondrial electron transport, succinate to ubiquinone)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0006783"(heme biosynthetic process)|go:"GO:0006811"(ion transport)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008199"(ferric iron binding)|go:"GO:0010040"("response to iron(II) ion")|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0018283"(iron incorporation into metallo-sulfur cluster)|go:"GO:0034986"(iron chaperone activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|interpro:IPR002908(Frataxin-like)|interpro:IPR017789(Frataxin)|interpro:IPR020895|interpro:IPR036524|rcsb pdb:2FQL|rcsb pdb:2GA5|rcsb pdb:3OEQ|rcsb pdb:3OER|rcsb pdb:4EC2|rcsb pdb:5T0V|rcsb pdb:5TRE|reactome:R-SCE-1268020|reactome:R-SCE-1362409|go:"GO:0008198"(ferrous iron binding)|sgd:YDL120W(identity)	-	-	crc64:AB1FF7478EF0E5D6	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:IGh7vC68gMLe+tAVGM4gc0rzc6Y9606	rogid:4UcroTodEXb/5+xHGpnXDXf/rd8559292	intact-crc:D827861A9D6C19B2|rigid:ATP/kj+Z6lPImhni88ySl6WER7c	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q07732	uniprotkb:Q96BR9	intact:EBI-33406|ensemblfungi:YDL239C|uniprotkb:D6VRB7	intact:EBI-742740|uniprotkb:Q8IUL5|uniprotkb:Q8IWR9|uniprotkb:Q8N2Y5|uniprotkb:Q96BX0|ensembl:ENSP00000362609	psi-mi:ady3_yeast(display_long)|uniprotkb:YDL239C(locus name)|uniprotkb:ADY3(gene name)|psi-mi:ADY3(display_short)	psi-mi:zbt8a_human(display_long)|uniprotkb:ZBTB8A(gene name)|psi-mi:ZBTB8A(display_short)|uniprotkb:BOZF1(gene name synonym)|uniprotkb:BTB/POZ and zinc-finger domain-containing factor(gene name synonym)|uniprotkb:BTB/POZ and zinc-finger domains factor on chromosome 1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11536089|imex:IM-24995-1441	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010042.2|sgd:S000002398|ensemblfungi:YDL239C(gene)|ensemblfungi:YDL239C_mRNA(transcript)|go:"GO:0000001"(mitochondrion inheritance)|go:"GO:0005628"(prospore membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0030435"(sporulation resulting in formation of a cellular spore)|go:"GO:0030476"(ascospore wall assembly)|go:"GO:0032120"(ascospore-type prospore membrane formation)|go:"GO:0051301"(cell division)|go:"GO:0070056"(prospore membrane leading edge)|interpro:IPR021750|mint:Q07732|dip:DIP-1811N|sgd:YDL239C(identity)	ensembl:ENSG00000160062(gene)|ensembl:ENST00000373510(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|refseq:NP_001035531.2|refseq:NP_001278425.1|entrezgene/locuslink:653121(identity)	-	crc64:46F17474F30FD3D9	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Cmac2NLDdbBzVKnJfFricfeeX24559292	rogid:tsrPT2tHvuBryODKgRXnceXz9s09606	intact-crc:68621CC6ACDADCB4|rigid:4nDxFkyXOQeI2CPShuXwWPWA6ew	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q07732	uniprotkb:Q8NA61-2	intact:EBI-33406|ensemblfungi:YDL239C|uniprotkb:D6VRB7	intact:EBI-11524851|ensembl:ENSP00000368249|ensembl:ENSP00000480148	psi-mi:ady3_yeast(display_long)|uniprotkb:YDL239C(locus name)|uniprotkb:ADY3(gene name)|psi-mi:ADY3(display_short)	psi-mi:q8na61-2(display_long)|uniprotkb:CBY2(gene name)|psi-mi:CBY2(display_short)|uniprotkb:SPERT(gene name synonym)|uniprotkb:Spermatid-associated protein(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11536080|imex:IM-24995-1440	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010042.2|sgd:S000002398|ensemblfungi:YDL239C(gene)|ensemblfungi:YDL239C_mRNA(transcript)|go:"GO:0000001"(mitochondrion inheritance)|go:"GO:0005628"(prospore membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0030435"(sporulation resulting in formation of a cellular spore)|go:"GO:0030476"(ascospore wall assembly)|go:"GO:0032120"(ascospore-type prospore membrane formation)|go:"GO:0051301"(cell division)|go:"GO:0070056"(prospore membrane leading edge)|interpro:IPR021750|mint:Q07732|dip:DIP-1811N|sgd:YDL239C(identity)	intact:EBI-741724(isoform-parent)|ensembl:ENSG00000174015(gene)|ensembl:ENST00000378966(transcript)|ensembl:ENST00000610924(transcript)|uniprotkb:Q8NA61-2(isoform-parent)|entrezgene/locuslink:220082(identity)	-	crc64:46F17474F30FD3D9	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Cmac2NLDdbBzVKnJfFricfeeX24559292	rogid:SogYcXGGMYRYzB9xKC5o0pEtsDs9606	intact-crc:402E88C1DE722C52|rigid:jaZwkCeZ60vDm4aVh1qzmjV6mYk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q07732	uniprotkb:Q53EZ4	intact:EBI-33406|ensemblfungi:YDL239C|uniprotkb:D6VRB7	intact:EBI-747776|uniprotkb:Q32WF5|uniprotkb:Q3MV20|uniprotkb:Q5VY28|uniprotkb:Q6N034|ensembl:ENSP00000360540|uniprotkb:Q96H32|uniprotkb:Q9NVS7|uniprotkb:B2RDG8|intact:EBI-10173536|uniprotkb:D3DR37|intact:EBI-28973801	psi-mi:ady3_yeast(display_long)|uniprotkb:YDL239C(locus name)|uniprotkb:ADY3(gene name)|psi-mi:ADY3(display_short)	psi-mi:cep55_human(display_long)|uniprotkb:Up-regulated in colon cancer 6(gene name synonym)|uniprotkb:CEP55(gene name)|psi-mi:CEP55(display_short)|uniprotkb:URCC6(gene name synonym)|uniprotkb:C10orf3(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11536071|imex:IM-24995-1439	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010042.2|sgd:S000002398|ensemblfungi:YDL239C(gene)|ensemblfungi:YDL239C_mRNA(transcript)|go:"GO:0000001"(mitochondrion inheritance)|go:"GO:0005628"(prospore membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0030435"(sporulation resulting in formation of a cellular spore)|go:"GO:0030476"(ascospore wall assembly)|go:"GO:0032120"(ascospore-type prospore membrane formation)|go:"GO:0051301"(cell division)|go:"GO:0070056"(prospore membrane leading edge)|interpro:IPR021750|mint:Q07732|dip:DIP-1811N|sgd:YDL239C(identity)	refseq:NP_001120654.1|refseq:NP_060601.3|ensembl:ENSG00000138180(gene)|ensembl:ENST00000371485(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0014066"(regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0030496"(midbody)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042802"(identical protein binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0061952"(midbody abscission)|go:"GO:0090543"(Flemming body)|go:"GO:1904888"(cranial skeletal system development)|interpro:IPR022008|interpro:IPR038926|mint:Q53EZ4|rcsb pdb:3E1R|rcsb pdb:3WUT|rcsb pdb:3WUU|rcsb pdb:3WUV|go:"GO:0005814"(centriole)|ensembl:ENSP00000360540|dip:DIP-44581N|entrezgene/locuslink:55165(identity)	-	crc64:46F17474F30FD3D9	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Cmac2NLDdbBzVKnJfFricfeeX24559292	rogid:tuo36vVb8ZgPDR81YjZFNEg559w9606	intact-crc:32F43EDE7D85D62B|rigid:6wOQ2W+NyTq4Z43Gtutq8hrUUEs	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q07540	uniprotkb:Q96DZ9-2	intact:EBI-2206814|uniprotkb:D6VRN0|ensemblfungi:YDL120W	intact:EBI-11522780|ensembl:ENSP00000352270|ensembl:ENSP00000497215	psi-mi:frda_yeast(display_long)|uniprotkb:YFH1(gene name)|psi-mi:YFH1(display_short)|uniprotkb:YDL120W(locus name)	psi-mi:q96dz9-2(display_long)|uniprotkb:CMTM5(gene name)|psi-mi:CMTM5(display_short)|uniprotkb:CKLFSF5(gene name synonym)|uniprotkb:Chemokine-like factor superfamily member 5(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11536062|imex:IM-24995-1438	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-7485N|refseq:NP_010163.1|sgd:S000002278|mint:Q07540|ensemblfungi:YDL120W(gene)|ensemblfungi:YDL120W_mRNA(transcript)|go:"GO:0004322"(ferroxidase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006121"(mitochondrial electron transport, succinate to ubiquinone)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0006783"(heme biosynthetic process)|go:"GO:0006811"(ion transport)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008199"(ferric iron binding)|go:"GO:0010040"("response to iron(II) ion")|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0018283"(iron incorporation into metallo-sulfur cluster)|go:"GO:0034986"(iron chaperone activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|interpro:IPR002908(Frataxin-like)|interpro:IPR017789(Frataxin)|interpro:IPR020895|interpro:IPR036524|rcsb pdb:2FQL|rcsb pdb:2GA5|rcsb pdb:3OEQ|rcsb pdb:3OER|rcsb pdb:4EC2|rcsb pdb:5T0V|rcsb pdb:5TRE|reactome:R-SCE-1268020|reactome:R-SCE-1362409|go:"GO:0008198"(ferrous iron binding)|sgd:YDL120W(identity)	ensembl:ENSG00000166091(gene)|ensembl:ENST00000359320(transcript)|ensembl:ENST00000649278(transcript)|intact:EBI-2548702(isoform-parent)|uniprotkb:Q96DZ9-2(isoform-parent)|entrezgene/locuslink:116173(identity)	-	crc64:AB1FF7478EF0E5D6	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:4UcroTodEXb/5+xHGpnXDXf/rd8559292	rogid:2TJ7rZKQNb5hH5gz9i+ujOEOIOg9606	intact-crc:D8C98549C8006EEB|rigid:TeTvZ46aWQK4pl4xiAKjWRnNeIU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q07821	uniprotkb:Q13137	intact:EBI-27136|uniprotkb:D6VXX7|ensemblfungi:YLL027W	intact:EBI-739580|uniprotkb:B4DDC4|uniprotkb:E7ENK0|uniprotkb:Q53FQ5|uniprotkb:Q53HB5|uniprotkb:Q6IBN9|uniprotkb:Q9BTF7|uniprotkb:B2RBT0|ensembl:ENSP00000258947|uniprotkb:B4E0C0|uniprotkb:E7ETP5|uniprotkb:B4DDT4|uniprotkb:B4DP36|uniprotkb:E9PBE5	psi-mi:isa1_yeast(display_long)|uniprotkb:YLL027W(locus name)|uniprotkb:ISA1(gene name)|psi-mi:ISA1(display_short)	psi-mi:caco2_human(display_long)|uniprotkb:CALCOCO2(gene name)|psi-mi:CALCOCO2(display_short)|uniprotkb:NDP52(gene name synonym)|uniprotkb:Nuclear domain 10 protein NDP52(gene name synonym)|uniprotkb:Antigen nuclear dot 52 kDa protein(gene name synonym)|uniprotkb:Nuclear dot protein 52(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11536127|imex:IM-24995-1445	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013073.1|sgd:S000003950|mint:Q07821|dip:DIP-1394N|ensemblfungi:YLL027W(gene)|ensemblfungi:YLL027W_mRNA(transcript)|go:"GO:0005506"(iron ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0009102"(biotin biosynthetic process)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0051536"(iron-sulfur cluster binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|go:"GO:0106035"(protein maturation by [4Fe-4S] cluster transfer)|interpro:IPR000361(HesB/YadR/YfhF-like)|interpro:IPR016092(HesB/YadR/YfhF)|interpro:IPR017870|interpro:IPR035903|reactome:R-SCE-1362409|sgd:YLL027W(identity)	refseq:NP_001248319.1|refseq:NP_001248320.1|refseq:NP_001248322.1|refseq:NP_005822.1|ensembl:ENSG00000136436(gene)|ensembl:ENST00000258947(transcript)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016032"(viral process)|go:"GO:0016605"(PML body)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0098792"(xenophagy)|go:"GO:1901098"(positive regulation of autophagosome maturation)|interpro:IPR041611|interpro:IPR041641|mint:Q13137|rcsb pdb:2MXP|rcsb pdb:3VVV|rcsb pdb:3VVW|rcsb pdb:4GXL|rcsb pdb:4HAN|rcsb pdb:4XKL|rcsb pdb:5AAQ|rcsb pdb:5Z7A|rcsb pdb:5Z7L|refseq:NP_001248324.1|dip:DIP-57534N|entrezgene/locuslink:10241(identity)	-	crc64:226C286B4F80DE6D	crc64:609B121DA1A9DCB8	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:QD74jkP7pZD875xxXj5J2YPKb5g559292	rogid:N/GPJUGBK+Dh5Cg+csmafphuo9M9606	intact-crc:FBA4DC615508B537|rigid:/QlFAJZFEm1z8taqFaGOjmznxy4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q07732	uniprotkb:Q9Y2J4	intact:EBI-33406|ensemblfungi:YDL239C|uniprotkb:D6VRB7	intact:EBI-746752|intact:EBI-28986657|ensembl:ENSP00000409999|uniprotkb:Q53EP1|uniprotkb:Q96F99|uniprotkb:Q9UKB4|uniprotkb:A8K6F1|uniprotkb:B7Z5Q1|uniprotkb:E9PHW3	psi-mi:ady3_yeast(display_long)|uniprotkb:YDL239C(locus name)|uniprotkb:ADY3(gene name)|psi-mi:ADY3(display_short)	psi-mi:amol2_human(display_long)|uniprotkb:Leman coiled-coil protein(gene name synonym)|uniprotkb:AMOTL2(gene name)|psi-mi:AMOTL2(display_short)|uniprotkb:KIAA0989(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11536116|imex:IM-24995-1444	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010042.2|sgd:S000002398|ensemblfungi:YDL239C(gene)|ensemblfungi:YDL239C_mRNA(transcript)|go:"GO:0000001"(mitochondrion inheritance)|go:"GO:0005628"(prospore membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0030435"(sporulation resulting in formation of a cellular spore)|go:"GO:0030476"(ascospore wall assembly)|go:"GO:0032120"(ascospore-type prospore membrane formation)|go:"GO:0051301"(cell division)|go:"GO:0070056"(prospore membrane leading edge)|interpro:IPR021750|mint:Q07732|dip:DIP-1811N|sgd:YDL239C(identity)	refseq:NP_001265612.1|refseq:NP_001265614.1|ensembl:ENSG00000114019(gene)|refseq:XP_006713717.1|refseq:NP_057285.3|refseq:XP_011511183.1|ensembl:ENST00000422605(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0003365"(establishment of cell polarity involved in ameboidal cell migration)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0035329"(hippo signaling)|go:"GO:0055037"(recycling endosome)|interpro:IPR009114(Angiomotin)|interpro:IPR024646|mint:Q9Y2J4|reactome:R-HSA-2028269|refseq:XP_016862069.1|refseq:XP_016862070.1|refseq:XP_016862071.1|ensembl:ENST00000249883|ensembl:ENSP00000249883|ensembl:ENSP00000409999|ensembl:ENST00000513145|ensembl:ENSP00000425475|ensembl:ENST00000514516|ensembl:ENSP00000424765|dip:DIP-57510N|entrezgene/locuslink:51421(identity)	-	crc64:46F17474F30FD3D9	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Cmac2NLDdbBzVKnJfFricfeeX24559292	rogid:SHtKAcLLnTpSSLwVE7yQ1WECoZk9606	intact-crc:D3D015E5FA06C004|rigid:O4SyFP0fLm1NYk8An6KJOIssr18	false	-	sufficient binding region:314-779	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q07732	uniprotkb:Q96IK5	intact:EBI-33406|ensemblfungi:YDL239C|uniprotkb:D6VRB7	intact:EBI-2548508|ensembl:ENSP00000282570|uniprotkb:Q9H826|uniprotkb:Q9H8V7|uniprotkb:Q9H927	psi-mi:ady3_yeast(display_long)|uniprotkb:YDL239C(locus name)|uniprotkb:ADY3(gene name)|psi-mi:ADY3(display_short)	psi-mi:gmcl1_human(display_long)|uniprotkb:GMCL1(gene name)|psi-mi:GMCL1(display_short)|uniprotkb:GCL(gene name synonym)|uniprotkb:BTBD13(gene name synonym)|uniprotkb:SPATA29(gene name synonym)|uniprotkb:Spermatogenesis-associated protein 29(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11536107|imex:IM-24995-1443	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010042.2|sgd:S000002398|ensemblfungi:YDL239C(gene)|ensemblfungi:YDL239C_mRNA(transcript)|go:"GO:0000001"(mitochondrion inheritance)|go:"GO:0005628"(prospore membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0030435"(sporulation resulting in formation of a cellular spore)|go:"GO:0030476"(ascospore wall assembly)|go:"GO:0032120"(ascospore-type prospore membrane formation)|go:"GO:0051301"(cell division)|go:"GO:0070056"(prospore membrane leading edge)|interpro:IPR021750|mint:Q07732|dip:DIP-1811N|sgd:YDL239C(identity)	ensembl:ENSG00000087338(gene)|ensembl:ENST00000282570(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0007281"(germ cell development)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016363"(nuclear matrix)|go:"GO:0042802"(identical protein binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR043380|refseq:NP_848526.1|entrezgene/locuslink:64395(identity)	-	crc64:46F17474F30FD3D9	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Cmac2NLDdbBzVKnJfFricfeeX24559292	rogid:ED8yqySVu7BWxpw3DUSNBZSQWrk9606	intact-crc:B8840B50BE68922F|rigid:tPzkqD4O/YtqXvlondCuqaUq5Yk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96CN9	uniprotkb:Q07732	intact:EBI-746252|uniprotkb:Q9H6N7|ensembl:ENSP00000318821	intact:EBI-33406|ensemblfungi:YDL239C|uniprotkb:D6VRB7	psi-mi:gcc1_human(display_long)|uniprotkb:Golgi coiled-coil protein 1(gene name synonym)|uniprotkb:GCC1(gene name)|psi-mi:GCC1(display_short)	psi-mi:ady3_yeast(display_long)|uniprotkb:YDL239C(locus name)|uniprotkb:ADY3(gene name)|psi-mi:ADY3(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11536098|imex:IM-24995-1442	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_078799.2|ensembl:ENSG00000179562(gene)|ensembl:ENST00000321407(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0031267"(small GTPase binding)|interpro:IPR000237(GRIP)|reactome:R-HSA-6811440|go:"GO:0000138"(Golgi trans cisterna)|entrezgene/locuslink:79571(identity)	refseq:NP_010042.2|sgd:S000002398|ensemblfungi:YDL239C(gene)|ensemblfungi:YDL239C_mRNA(transcript)|go:"GO:0000001"(mitochondrion inheritance)|go:"GO:0005628"(prospore membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0030435"(sporulation resulting in formation of a cellular spore)|go:"GO:0030476"(ascospore wall assembly)|go:"GO:0032120"(ascospore-type prospore membrane formation)|go:"GO:0051301"(cell division)|go:"GO:0070056"(prospore membrane leading edge)|interpro:IPR021750|mint:Q07732|dip:DIP-1811N|sgd:YDL239C(identity)	-	-	crc64:46F17474F30FD3D9	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:SCI+peKjPIvl/HbUUpHGM++qiRE9606	rogid:Cmac2NLDdbBzVKnJfFricfeeX24559292	intact-crc:0EA1768A990BC183|rigid:08Jt5ox7qz3ClHaE+1psuSQMvA0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q0VDD7	uniprotkb:Q07951	intact:EBI-741210|ensembl:ENSP00000465822|ensembl:ENSP00000500215|uniprotkb:Q13411|uniprotkb:Q8N825|uniprotkb:Q96D63|uniprotkb:Q9BU49	intact:EBI-31959|uniprotkb:D6VY23|ensemblfungi:YLR021W	psi-mi:brme1_human(display_long)|uniprotkb:BRME1(gene name)|psi-mi:BRME1(display_short)|uniprotkb:C19orf57(gene name synonym)|uniprotkb:Pre-T/NK cell-associated protein 3B3(gene name synonym)	psi-mi:poc3_yeast(display_long)|uniprotkb:POC3(gene name synonym)|uniprotkb:Increased recombination centers protein 25(gene name synonym)|uniprotkb:IRC25(gene name)|psi-mi:IRC25(display_short)|uniprotkb:DMP2(gene name synonym)|uniprotkb:YLR021W(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11536154|imex:IM-24995-1448	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_077299.3|ensembl:ENSG00000132016(gene)|ensembl:ENSG00000288152(gene)|ensembl:ENST00000586783(transcript)|ensembl:ENST00000672170(transcript)|go:"GO:0005694"(chromosome)|go:"GO:0007144"(female meiosis I)|go:"GO:0007275"(multicellular organism development)|go:"GO:0007283"(spermatogenesis)|go:"GO:1990918"(double-strand break repair involved in meiotic recombination)|interpro:IPR031441|refseq:NP_001332773.1|entrezgene/locuslink:79173(identity)	refseq:NP_013121.1|sgd:S000004011|dip:DIP-4747N|mint:Q07951|ensemblfungi:YLR021W(gene)|ensemblfungi:YLR021W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043248"(proteasome assembly)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|interpro:IPR018854|rcsb pdb:2Z5B|rcsb pdb:2Z5C|sgd:YLR021W(identity)	-	-	crc64:6CA25E8ED0491EE2	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:YUbAjs5ZmWOPWRA9kq5qRZRioR49606	rogid:5xcWnXqOt0DxQvelDvtc8ob2bj0559292	intact-crc:B977256A4B50B39F|rigid:35A6MX4dE+GvyRN0fhmWQM9BMAo	false	sufficient binding region:336-668	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q07951	uniprotkb:Q8N5R6	intact:EBI-31959|uniprotkb:D6VY23|ensemblfungi:YLR021W	intact:EBI-740841|intact:EBI-953781|uniprotkb:B3KQ49|uniprotkb:A8K3U4|uniprotkb:A8MPQ6|uniprotkb:A8MV61|uniprotkb:A8MVU9|uniprotkb:Q9H5Q6|uniprotkb:Q8TAX6|intact:EBI-2320546|intact:EBI-11522976	psi-mi:poc3_yeast(display_long)|uniprotkb:POC3(gene name synonym)|uniprotkb:Increased recombination centers protein 25(gene name synonym)|uniprotkb:IRC25(gene name)|psi-mi:IRC25(display_short)|uniprotkb:DMP2(gene name synonym)|uniprotkb:YLR021W(locus name)	psi-mi:ccd33_human(display_long)|uniprotkb:CCDC33(gene name)|psi-mi:CCDC33(display_short)|uniprotkb:Cancer/testis antigen 61(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11536145|imex:IM-24995-1447	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013121.1|sgd:S000004011|dip:DIP-4747N|mint:Q07951|ensemblfungi:YLR021W(gene)|ensemblfungi:YLR021W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043248"(proteasome assembly)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|interpro:IPR018854|rcsb pdb:2Z5B|rcsb pdb:2Z5C|sgd:YLR021W(identity)	refseq:NP_079331.3|interpro:IPR000008(C2 calcium-dependent membrane targeting)|go:"GO:0005777"(peroxisome)|refseq:NP_001274110.1|refseq:NP_877592.2|mint:Q8N5R6|interpro:IPR035892|interpro:IPR039889|entrezgene/locuslink:80125(identity)	-	crc64:6CA25E8ED0491EE2	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2021/11/30	rogid:5xcWnXqOt0DxQvelDvtc8ob2bj0559292	rogid:eEIn7pQyfdHWx8TeLJpYy0i/gww9606	intact-crc:C07D1E28F0409B28|rigid:k/XPBxFV+++TO+0BhS/Z4sYVhQQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O96006	uniprotkb:Q07887	intact:EBI-740037|uniprotkb:Q96BY4|ensembl:ENSP00000370616|ensembl:ENSP00000370620|ensembl:ENSP00000370621|ensembl:ENSP00000498725	intact:EBI-33243|uniprotkb:D6VXV9|ensemblfungi:YLL049W	psi-mi:zbed1_human(display_long)|uniprotkb:ZBED1(gene name)|psi-mi:ZBED1(display_short)|uniprotkb:ALTE(gene name synonym)|uniprotkb:DREF(gene name synonym)|uniprotkb:KIAA0785(gene name synonym)|uniprotkb:TRAMP(gene name synonym)|uniprotkb:dREF homolog(gene name synonym)|uniprotkb:Putative Ac-like transposable element(gene name synonym)|uniprotkb:DNA replication-related element-binding factor(gene name synonym)|uniprotkb:Zinc finger BED domain-containing protein 1(gene name synonym)|uniprotkb:hDREF(gene name synonym)	psi-mi:ldb18_yeast(display_long)|uniprotkb:Low dye-binding protein 18(gene name synonym)|uniprotkb:LDB18(gene name)|psi-mi:LDB18(display_short)|uniprotkb:YLL049W(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11536136|imex:IM-24995-1446	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164606.1|refseq:NP_001164607.1|refseq:NP_004720.1|ensembl:ENSG00000214717(gene)|ensembl:ENST00000381218(transcript)|ensembl:ENST00000381222(transcript)|ensembl:ENST00000381223(transcript)|ensembl:ENST00000652001(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0031965"(nuclear membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044828"(negative regulation by host of viral genome replication)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0061665"(SUMO ligase activity)|go:"GO:1990466"(protein autosumoylation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003656(Zinc finger, BED-type predicted)|interpro:IPR008906(HAT dimerisation)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR036236|mint:O96006|rcsb pdb:2CT5|reactome:R-HSA-4551638|go:"GO:0005813"(centrosome)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016605"(PML body)|entrezgene/locuslink:9189(identity)	sgd:S000003972|refseq:NP_013051.1|dip:DIP-1932N|ensemblfungi:YLL049W(gene)|ensemblfungi:YLL049W_mRNA(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0005869"(dynactin complex)|sgd:YLL049W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:jl97ZV2Kz5YAmQKktWt/wk7OkRw9606	rogid:oTvD3VEb0ZAfYezSviDPi8wVGxg559292	intact-crc:E5DCF039D6DACBB1|rigid:LMPnmhfxp/6331BqlNLbAhctQcA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q07978	uniprotkb:G5E962	intact:EBI-38683|uniprotkb:D6VY33|ensemblfungi:YLR031W	intact:EBI-11525615|ensembl:ENSP00000328177	psi-mi:yl031_yeast(display_long)|uniprotkb:YLR031W(locus name)	psi-mi:g5e962_human(display_long)|uniprotkb:hCG_1644200(orf name)|uniprotkb:MAGEA11(gene name)|psi-mi:MAGEA11(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11536165|imex:IM-24995-1449	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000004021|refseq:NP_013131.1|dip:DIP-4435N|ensemblfungi:YLR031W(gene)|ensemblfungi:YLR031W_mRNA(transcript)|sgd:YLR031W(identity)	refseq:NP_001011544.1|ensembl:ENSG00000185247(gene)|ensembl:ENST00000333104(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016604"(nuclear body)|interpro:IPR002190(MAGE protein)|interpro:IPR021072|interpro:IPR030099|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|entrezgene/locuslink:4110(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:T3r2tgTMVd+abiwf7/Ccb/QJ2ZQ559292	rogid:sVB0aA6yibWUx/d2SE+pwpKKgtI9606	intact-crc:D818C6801B2CA204|rigid:9pXV7NJ/j3aIqFAFo5bgeW9LAzI	false	-	sufficient binding region:82-400	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q07978	uniprotkb:Q15311	intact:EBI-38683|uniprotkb:D6VY33|ensemblfungi:YLR031W	intact:EBI-749285|uniprotkb:D3DUI0|ensembl:ENSP00000019317|ensembl:ENSP00000372924	psi-mi:yl031_yeast(display_long)|uniprotkb:YLR031W(locus name)	psi-mi:rbp1_human(display_long)|uniprotkb:Ral-interacting protein 1(gene name synonym)|uniprotkb:76 kDa Ral-interacting protein(gene name synonym)|uniprotkb:Dinitrophenyl S-glutathione ATPase(gene name synonym)|uniprotkb:RALBP1(gene name)|psi-mi:RALBP1(display_short)|uniprotkb:RLIP1(gene name synonym)|uniprotkb:RLIP76(gene name synonym)|uniprotkb:RLIP(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11536176|imex:IM-24995-1450	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000004021|refseq:NP_013131.1|dip:DIP-4435N|ensemblfungi:YLR031W(gene)|ensemblfungi:YLR031W_mRNA(transcript)|sgd:YLR031W(identity)	refseq:NP_006779.1|ensembl:ENSG00000017797(gene)|ensembl:ENST00000019317(transcript)|ensembl:ENST00000383432(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0006935"(chemotaxis)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008559"(ABC-type xenobiotic transporter activity)|go:"GO:0015431"(ABC-type glutathione S-conjugate transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032489"(regulation of Cdc42 protein signal transduction)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0055085"(transmembrane transport)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:1900753"(doxorubicin transport)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR000198(RhoGAP)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR039767|mint:Q15311|rcsb pdb:2KWH|rcsb pdb:2KWI|rcsb pdb:2MBG|rcsb pdb:6ZQT|rcsb pdb:6ZRN|reactome:R-HSA-9013148|reactome:R-HSA-9013149|entrezgene/locuslink:10928(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:T3r2tgTMVd+abiwf7/Ccb/QJ2ZQ559292	rogid:6u1yy+UdGWJbJ9SiItSAp+CqeVk9606	intact-crc:72BE5BD5B196338F|rigid:0n9EzCn+UfVIyeu8uLmWUuWgaZ4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8WWB3	uniprotkb:Q07978	intact:EBI-740680|ensembl:ENSP00000361276|ensembl:ENSP00000361278|ensembl:ENSP00000402890|uniprotkb:Q5QP03|uniprotkb:Q5QP04|uniprotkb:Q6WNP4|uniprotkb:Q6ZU87|uniprotkb:A8K927	intact:EBI-38683|uniprotkb:D6VY33|ensemblfungi:YLR031W	psi-mi:dydc1_human(display_long)|uniprotkb:DYDC1(gene name)|psi-mi:DYDC1(display_short)|uniprotkb:DPY30D1(gene name synonym)|uniprotkb:RSD9(orf name)|uniprotkb:RSD-9(orf name)	psi-mi:yl031_yeast(display_long)|uniprotkb:YLR031W(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11536185|imex:IM-24995-1451	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_620167.1|ensembl:ENSG00000170788(gene)|ensembl:ENST00000372202(transcript)|ensembl:ENST00000372204(transcript)|ensembl:ENST00000421924(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0006348"|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|interpro:IPR007858(Dpy-30)|interpro:IPR037856|refseq:XP_011537636.1|refseq:XP_011537637.1|refseq:NP_001255982.1|refseq:XP_005269606.1|refseq:XP_005269607.1|entrezgene/locuslink:143241(identity)	sgd:S000004021|refseq:NP_013131.1|dip:DIP-4435N|ensemblfungi:YLR031W(gene)|ensemblfungi:YLR031W_mRNA(transcript)|sgd:YLR031W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:W6GUazYFXZGHGijUBpAJ5GiRuXA9606	rogid:T3r2tgTMVd+abiwf7/Ccb/QJ2ZQ559292	intact-crc:8B245D800E733656|rigid:L6aPc/q8SYVlXcsNAWhyn+g24+U	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q08144	uniprotkb:Q969F0	intact:EBI-19302|uniprotkb:D6W248|uniprotkb:E9P933|ensemblfungi:YOL018C	intact:EBI-743099|ensembl:ENSP00000359375	psi-mi:tlg2_yeast(display_long)|uniprotkb:YOL018C(locus name)|uniprotkb:TLG2(gene name)|psi-mi:TLG2(display_short)|uniprotkb:Syntaxin TLG2(gene name synonym)	psi-mi:fate1_human(display_long)|uniprotkb:Tumor antigen BJ-HCC-2(gene name synonym)|uniprotkb:Cancer/testis antigen 43(gene name synonym)|uniprotkb:FATE1(gene name)|psi-mi:FATE1(display_short)|uniprotkb:FATE(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11536221|imex:IM-24995-1455	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014624.1|sgd:S000005378|ensemblfungi:YOL018C(gene)|ensemblfungi:YOL018C_mRNA(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006673"(inositol phosphoceramide metabolic process)|go:"GO:0006675"(mannosyl-inositol phosphorylceramide metabolic process)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0031303"(integral component of endosome membrane)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0032527"(protein exit from endoplasmic reticulum)|go:"GO:0048278"(vesicle docking)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|interpro:IPR028673|reactome:R-SCE-6811440|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0006897"(endocytosis)|go:"GO:0006906"(vesicle fusion)|go:"GO:0009306"(protein secretion)|dip:DIP-4244N|mint:Q08144|sgd:YOL018C(identity)	refseq:NP_149076.1|ensembl:ENSG00000147378(gene)|ensembl:ENST00000370350(transcript)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|go:"GO:0051562"(negative regulation of mitochondrial calcium ion concentration)|interpro:IPR039153|interpro:IPR039433|mint:Q969F0|entrezgene/locuslink:89885(identity)	-	crc64:CEBD6FE11278B1F0	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:M7Ezt/D1lvPf/T8TrjQwtKNhFhw559292	rogid:Nm1N6lO92MHr5rIKC007oouF5RE9606	intact-crc:18AB43DB025C3E81|rigid:cQACnOQCbuaL/pzJ2LBnjJi+ikM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q08144	uniprotkb:Q8N6L0	intact:EBI-19302|uniprotkb:D6W248|uniprotkb:E9P933|ensemblfungi:YOL018C	intact:EBI-749265|uniprotkb:Q96MC3|ensembl:ENSP00000404220	psi-mi:tlg2_yeast(display_long)|uniprotkb:YOL018C(locus name)|uniprotkb:TLG2(gene name)|psi-mi:TLG2(display_short)|uniprotkb:Syntaxin TLG2(gene name synonym)	psi-mi:kash5_human(display_long)|uniprotkb:KASH5(gene name)|psi-mi:KASH5(display_short)|uniprotkb:CCDC155(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 155(gene name synonym)|uniprotkb:KASH domain-containing protein 5(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11536212|imex:IM-24995-1454	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014624.1|sgd:S000005378|ensemblfungi:YOL018C(gene)|ensemblfungi:YOL018C_mRNA(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006673"(inositol phosphoceramide metabolic process)|go:"GO:0006675"(mannosyl-inositol phosphorylceramide metabolic process)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0031303"(integral component of endosome membrane)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0032527"(protein exit from endoplasmic reticulum)|go:"GO:0048278"(vesicle docking)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|interpro:IPR028673|reactome:R-SCE-6811440|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0006897"(endocytosis)|go:"GO:0006906"(vesicle fusion)|go:"GO:0009306"(protein secretion)|dip:DIP-4244N|mint:Q08144|sgd:YOL018C(identity)	refseq:NP_653289.3|ensembl:ENSG00000161609(gene)|ensembl:ENST00000447857(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034397"(telomere localization)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051225"(spindle assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0090172"(microtubule cytoskeleton organization involved in homologous chromosome segregation)|go:"GO:0090220"(chromosome localization to nuclear envelope involved in homologous chromosome segregation)|go:"GO:0090619"(meiotic spindle pole)|interpro:IPR011992(EF-Hand type)|interpro:IPR028168|interpro:IPR028170|interpro:IPR039508|mint:Q8N6L0|rcsb pdb:6R2I|rcsb pdb:6WMF|entrezgene/locuslink:147872(identity)	-	crc64:CEBD6FE11278B1F0	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:M7Ezt/D1lvPf/T8TrjQwtKNhFhw559292	rogid:Wl9L7AcvDHCZuKjYLn8QgGIbZTc9606	intact-crc:0E4388D560AEC8F2|rigid:7rwn6m3XKT9W7TGcSkZG80H+Vtc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8NEC5	uniprotkb:Q07986	intact:EBI-744545|uniprotkb:Q96P76|ensembl:ENSP00000309052	intact:EBI-37985|uniprotkb:D6VY39|ensemblfungi:YLR036C	psi-mi:ctsr1_human(display_long)|uniprotkb:CATSPER1(gene name)|psi-mi:CATSPER1(display_short)	psi-mi:yl036_yeast(display_long)|uniprotkb:YLR036C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11536194|imex:IM-24995-1452	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_444282.3|ensembl:ENSG00000175294(gene)|ensembl:ENST00000312106(transcript)|go:"GO:0005227"(calcium activated cation channel activity)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007283"(spermatogenesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0031514"(motile cilium)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0036128"(CatSper complex)|go:"GO:0060296"(regulation of cilium beat frequency involved in ciliary motility)|interpro:IPR005821(Ion transport)|interpro:IPR027359|interpro:IPR028746|reactome:R-HSA-1300642|entrezgene/locuslink:117144(identity)	sgd:S000004026|refseq:NP_013137.1|dip:DIP-2127N|ensemblfungi:YLR036C(gene)|ensemblfungi:YLR036C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0016021"(integral component of membrane)|interpro:IPR031427|sgd:YLR036C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:hY8kq7xGiDrD6FydKByugAo0t+U9606	rogid:GGcRlz7wYc6R9SI/NTywlmxOu8Q559292	intact-crc:C284C6EECFE1E78A|rigid:J0wMoMK8ttPT5GRI+vP3FHWpcTs	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12846	uniprotkb:Q08144	intact:EBI-744942|uniprotkb:Q15525|ensembl:ENSP00000317714|uniprotkb:Q6FHE8|uniprotkb:A8MXY0	intact:EBI-19302|uniprotkb:D6W248|uniprotkb:E9P933|ensemblfungi:YOL018C	psi-mi:stx4_human(display_long)|uniprotkb:Renal carcinoma antigen NY-REN-31(gene name synonym)|uniprotkb:STX4(gene name)|psi-mi:STX4(display_short)|uniprotkb:STX4A(gene name synonym)	psi-mi:tlg2_yeast(display_long)|uniprotkb:YOL018C(locus name)|uniprotkb:TLG2(gene name)|psi-mi:TLG2(display_short)|uniprotkb:Syntaxin TLG2(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11536203|imex:IM-24995-1453	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000103496(gene)|refseq:NP_004595.2|ensembl:ENST00000313843(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0000322"(storage vacuole)|go:"GO:0002639"(positive regulation of immunoglobulin production)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005768"(endosome)|go:"GO:0005773"(vacuole)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006887"(exocytosis)|go:"GO:0006906"(vesicle fusion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016230"(sphingomyelin phosphodiesterase activator activity)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0032589"(neuron projection membrane)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035493"(SNARE complex assembly)|go:"GO:0035749"(myelin sheath adaxonal region)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0036477"(somatodendritic compartment)|go:"GO:0042581"(specific granule)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043197"(dendritic spine)|go:"GO:0043219"(lateral loop)|go:"GO:0043311"(positive regulation of eosinophil degranulation)|go:"GO:0045202"(synapse)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0048278"(vesicle docking)|go:"GO:0048284"(organelle fusion)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048787"(presynaptic active zone membrane)|go:"GO:0050921"(positive regulation of chemotaxis)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1902041"(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1903575"(cornified envelope assembly)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|reactome:R-HSA-114516|reactome:R-HSA-1236974|reactome:R-HSA-1445148|reactome:R-HSA-199992|reactome:R-HSA-449836|interpro:IPR006011(Syntaxin, N-terminal)|refseq:NP_001259025.1|entrezgene/locuslink:6810(identity)	refseq:NP_014624.1|sgd:S000005378|ensemblfungi:YOL018C(gene)|ensemblfungi:YOL018C_mRNA(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006673"(inositol phosphoceramide metabolic process)|go:"GO:0006675"(mannosyl-inositol phosphorylceramide metabolic process)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0031303"(integral component of endosome membrane)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0032527"(protein exit from endoplasmic reticulum)|go:"GO:0048278"(vesicle docking)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|interpro:IPR028673|reactome:R-SCE-6811440|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0006897"(endocytosis)|go:"GO:0006906"(vesicle fusion)|go:"GO:0009306"(protein secretion)|dip:DIP-4244N|mint:Q08144|sgd:YOL018C(identity)	-	-	crc64:CEBD6FE11278B1F0	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:NvOLGIGe/XO2aDPSpdPzrtKniZY9606	rogid:M7Ezt/D1lvPf/T8TrjQwtKNhFhw559292	intact-crc:B961A44503EDC6F3|rigid:Z47hgCTIBXp+/pzO7xUoEJ74PoY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q5JR59-3	uniprotkb:Q08204	intact:EBI-11522433|ensembl:ENSP00000370186	intact:EBI-34125|uniprotkb:D6W231|ensemblfungi:YOL034W	psi-mi:q5jr59-3(display_long)|uniprotkb:MTUS2(gene name)|psi-mi:MTUS2(display_short)|uniprotkb:CAZIP(gene name synonym)|uniprotkb:Cardiac zipper protein(gene name synonym)|uniprotkb:KIAA0774(gene name synonym)|uniprotkb:Microtubule plus-end tracking protein TIP150(gene name synonym)|uniprotkb:TIP150(gene name synonym)	psi-mi:smc5_yeast(display_long)|uniprotkb:SMC5(gene name)|psi-mi:SMC5(display_short)|uniprotkb:YOL034W(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11536230|imex:IM-24995-1456	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000132938(gene)|ensembl:ENST00000380808(transcript)|intact:EBI-742948(isoform-parent)|uniprotkb:Q5JR59-3(isoform-parent)|entrezgene/locuslink:23281(identity)	refseq:NP_014608.1|sgd:S000005394|mint:Q08204|dip:DIP-1979N|ensemblfungi:YOL034W(gene)|ensemblfungi:YOL034W_mRNA(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000725"(recombinational repair)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006281"(DNA repair)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0016925"(protein sumoylation)|go:"GO:0030915"(Smc5-Smc6 complex)|go:"GO:0051304"(chromosome separation)|go:"GO:0071139"(resolution of recombination intermediates)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR027131|interpro:IPR027417|rcsb pdb:3HTK|reactome:R-SCE-3108214|sgd:YOL034W(identity)	-	isoform-comment:No experimental confirmation available.	crc64:6752B96438CFB549	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:npId9tC7VoLN/jteoBiRbSYChPs9606	rogid:7EBoBNiTfotgfzhZ2+a+PcQTAqc559292	intact-crc:92452A831CE3CB18|rigid:5FCJttU5dvY+BGiAtowtRs3KLuQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9Y2D8	uniprotkb:Q08204	intact:EBI-2212028|uniprotkb:B4DFE3|uniprotkb:J3KR02|uniprotkb:A8K8W0|uniprotkb:D3DT13|uniprotkb:Q6P2P8|uniprotkb:Q6ULS1|uniprotkb:Q7L168|uniprotkb:Q9UIX0|intact:EBI-10964529|ensembl:ENSP00000340279	intact:EBI-34125|uniprotkb:D6W231|ensemblfungi:YOL034W	psi-mi:adip_human(display_long)|uniprotkb:SSX2IP(gene name)|psi-mi:SSX2IP(display_short)|uniprotkb:KIAA0923(gene name synonym)|uniprotkb:Afadin DIL domain-interacting protein(gene name synonym)|uniprotkb:SSX2-interacting protein(gene name synonym)	psi-mi:smc5_yeast(display_long)|uniprotkb:SMC5(gene name)|psi-mi:SMC5(display_short)|uniprotkb:YOL034W(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11536252|imex:IM-24995-1458	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011538912.1|refseq:NP_001159765.1|refseq:NP_001159766.1|refseq:NP_001159767.1|refseq:NP_001159889.1|refseq:NP_054740.3|refseq:XP_005270484.1|refseq:XP_005270485.1|refseq:XP_006710394.1|refseq:XP_016855723.1|ensembl:ENSG00000117155(gene)|ensembl:ENST00000342203(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005912"(adherens junction)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031252"(cell leading edge)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0035735"(intraciliary transport involved in cilium assembly)|go:"GO:0036064"(ciliary basal body)|go:"GO:0060271"(cilium assembly)|go:"GO:2000145"(regulation of cell motility)|interpro:IPR021622|mint:Q9Y2D8|entrezgene/locuslink:117178(identity)	refseq:NP_014608.1|sgd:S000005394|mint:Q08204|dip:DIP-1979N|ensemblfungi:YOL034W(gene)|ensemblfungi:YOL034W_mRNA(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000725"(recombinational repair)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006281"(DNA repair)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0016925"(protein sumoylation)|go:"GO:0030915"(Smc5-Smc6 complex)|go:"GO:0051304"(chromosome separation)|go:"GO:0071139"(resolution of recombination intermediates)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR027131|interpro:IPR027417|rcsb pdb:3HTK|reactome:R-SCE-3108214|sgd:YOL034W(identity)	-	-	crc64:6752B96438CFB549	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:E0VeMRF9SrpQKSJFP01XEbMjeF89606	rogid:7EBoBNiTfotgfzhZ2+a+PcQTAqc559292	intact-crc:F3E7B2E7CF31658B|rigid:wstO6eypXHeYmVjGP2B+Nh8mE2M	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q08204	uniprotkb:Q9UKS7-2	intact:EBI-34125|uniprotkb:D6W231|ensemblfungi:YOL034W	intact:EBI-11536241|ensembl:ENSP00000363439	psi-mi:smc5_yeast(display_long)|uniprotkb:SMC5(gene name)|psi-mi:SMC5(display_short)|uniprotkb:YOL034W(locus name)	psi-mi:q9uks7-2(display_long)|uniprotkb:HELIOS(gene name synonym)|uniprotkb:Ikaros family zinc finger protein 2(gene name synonym)|uniprotkb:ZNFN1A2(gene name synonym)|uniprotkb:Helios 1v(isoform synonym)|uniprotkb:IKZF2(gene name)|psi-mi:IKZF2(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11536239|imex:IM-24995-1457	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014608.1|sgd:S000005394|mint:Q08204|dip:DIP-1979N|ensemblfungi:YOL034W(gene)|ensemblfungi:YOL034W_mRNA(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000725"(recombinational repair)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006281"(DNA repair)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0016925"(protein sumoylation)|go:"GO:0030915"(Smc5-Smc6 complex)|go:"GO:0051304"(chromosome separation)|go:"GO:0071139"(resolution of recombination intermediates)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR027131|interpro:IPR027417|rcsb pdb:3HTK|reactome:R-SCE-3108214|sgd:YOL034W(identity)	intact:EBI-3893057(isoform-parent)|ensembl:ENSG00000030419(gene)|ensembl:ENST00000374319(transcript)|uniprotkb:Q9UKS7-2(isoform-parent)|entrezgene/locuslink:22807(identity)	-	crc64:6752B96438CFB549	isoform-comment:"Contains a glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) at position 95."	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:7EBoBNiTfotgfzhZ2+a+PcQTAqc559292	rogid:BPYW+3VwNBn9+7Qbh63ii8np0F09606	intact-crc:F65983271B0CC33A|rigid:BcCyHJrysULnVjzARp46XnwdqmM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q08224	uniprotkb:Q9C0F1	intact:EBI-35298|uniprotkb:Q05664|uniprotkb:Q6B2F0|uniprotkb:D6W212|ensemblfungi:YOL055C	intact:EBI-744115|uniprotkb:A8K8W9|uniprotkb:B3KT53|uniprotkb:Q8IXZ4|uniprotkb:A8MW11|uniprotkb:D3DP42|ensembl:ENSP00000296519|ensembl:ENSP00000380009|ensembl:ENSP00000423153	psi-mi:thi20_yeast(display_long)|uniprotkb:THI20(gene name)|psi-mi:THI20(display_short)|uniprotkb:Hydroxymethylpyrimidine kinase(gene name synonym)|uniprotkb:YOL055C(locus name)|uniprotkb:O1239(orf name)|uniprotkb:Hydroxymethylpyrimidine phosphate kinase(gene name synonym)	psi-mi:cep44_human(display_long)|uniprotkb:HBV PreS1-transactivated protein 3(gene name synonym)|uniprotkb:CEP44(gene name)|psi-mi:CEP44(display_short)|uniprotkb:KIAA1712(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11536261|imex:IM-24995-1459	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014586.1|sgd:S000005416|dip:DIP-8852N|ensemblfungi:YOL055C(gene)|ensemblfungi:YOL055C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0008902"(hydroxymethylpyrimidine kinase activity)|go:"GO:0008972"(phosphomethylpyrimidine kinase activity)|go:"GO:0009228"(thiamine biosynthetic process)|go:"GO:0009229"(thiamine diphosphate biosynthetic process)|go:"GO:0009230"(thiamine catabolic process)|go:"GO:0050334"(thiaminase activity)|interpro:IPR004305(TENA/THI-4 protein/Coenzyme PQQ biosynthesis protein C)|interpro:IPR004399(Phosphomethylpyrimidine kinase type-2)|interpro:IPR013749(Phosphomethylpyrimidine kinase type-1)|interpro:IPR016084(Haem oxygenase-like, multi-helical)|interpro:IPR027574|interpro:IPR029056|rcsb pdb:3RM5|sgd:YOL055C(identity)	refseq:NP_001035247.1|refseq:NP_001138786.1|refseq:XP_011530587.1|refseq:XP_011530588.1|refseq:XP_011530589.1|refseq:XP_016864143.1|refseq:XP_016864144.1|ensembl:ENSG00000164118(gene)|ensembl:ENST00000296519(transcript)|ensembl:ENST00000396791(transcript)|ensembl:ENST00000503780(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007099"(centriole replication)|go:"GO:0008017"(microtubule binding)|go:"GO:0010457"(centriole-centriole cohesion)|go:"GO:0030496"(midbody)|interpro:IPR029157|interpro:IPR033603|mint:Q9C0F1|entrezgene/locuslink:80817(identity)	-	crc64:D57D1C6B693EE401	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:8Z2moCtUE4aAGFn00SHe4PMjdT4559292	rogid:gDTC64oDhudGdsssC7v+suIHZkA9606	intact-crc:A041222CAC14E295|rigid:uD4lCFeYF3kBtM74SDEXQnnErKA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q08273	uniprotkb:O43791	intact:EBI-31686|uniprotkb:D6W1T5|ensemblfungi:YOL133W	intact:EBI-743549|uniprotkb:Q53HJ1|uniprotkb:B2R6S3|uniprotkb:D3DTW7|ensembl:ENSP00000240327|ensembl:ENSP00000377001|ensembl:ENSP00000420908|ensembl:ENSP00000424119|ensembl:ENSP00000425905|ensembl:ENSP00000426986|ensembl:ENSP00000499562	psi-mi:rbx1_yeast(display_long)|uniprotkb:E3 ubiquitin-protein ligase complex SCF subunit HRT1(gene name synonym)|uniprotkb:High level expression reduces Ty3 transposition protein 1(gene name synonym)|uniprotkb:HRT1(gene name)|psi-mi:HRT1(display_short)|uniprotkb:RBX1(gene name synonym)|uniprotkb:ROC1(gene name synonym)|uniprotkb:Regulator of cullins protein 1(gene name synonym)|uniprotkb:YOL133W(locus name)	psi-mi:spop_human(display_long)|uniprotkb:HIB homolog 1(gene name synonym)|uniprotkb:Roadkill homolog 1(gene name synonym)|uniprotkb:SPOP(gene name)|psi-mi:SPOP(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11536270|imex:IM-24995-1460	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014508.1|sgd:S000005493|dip:DIP-1373N|mint:Q08273|ensemblfungi:YOL133W(gene)|ensemblfungi:YOL133W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0035361"(Cul8-RING ubiquitin ligase complex)|go:"GO:0051301"(cell division)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097602"(cullin family protein binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR024766|reactome:R-SCE-5696395|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-68949|reactome:R-SCE-8854050|reactome:R-SCE-8951664|reactome:R-SCE-983168|sgd:YOL133W(identity)	refseq:NP_001007227.1|refseq:NP_001007228.1|refseq:NP_001007229.1|refseq:NP_001007230.1|refseq:NP_001007231.1|refseq:NP_003554.1|refseq:XP_005257780.1|refseq:XP_005257781.1|ensembl:ENSG00000121067(gene)|ensembl:ENST00000347630(transcript)|ensembl:ENST00000393328(transcript)|ensembl:ENST00000503676(transcript)|ensembl:ENST00000504102(transcript)|ensembl:ENST00000509079(transcript)|ensembl:ENST00000514121(transcript)|ensembl:ENST00000665825(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0016607"(nuclear speck)|go:"GO:0030162"(regulation of proteolysis)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR034089|mint:O43791|rcsb pdb:2CR2|rcsb pdb:3HQH|rcsb pdb:3HQI|rcsb pdb:3HQL|rcsb pdb:3HQM|rcsb pdb:3HSV|rcsb pdb:3HTM|rcsb pdb:3HU6|rcsb pdb:3IVB|rcsb pdb:3IVQ|rcsb pdb:3IVV|rcsb pdb:4EOZ|rcsb pdb:4HS2|rcsb pdb:4J8Z|rcsb pdb:4O1V|rcsb pdb:6F8F|rcsb pdb:6F8G|rcsb pdb:6I41|rcsb pdb:6I5P|rcsb pdb:6I68|rcsb pdb:6I7A|rcsb pdb:7D3D|rcsb pdb:7LIN|rcsb pdb:7LIO|rcsb pdb:7LIP|rcsb pdb:7LIQ|reactome:R-HSA-5632684|go:"GO:0005634"(nucleus)|refseq:XP_016880693.1|dip:DIP-50517N|entrezgene/locuslink:8405(identity)	-	crc64:A9C3193E48CAF881	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:7LBUfvb6zpWuPkbMDrEAnrMuJj8559292	rogid:PC9ofpvk14xwTnnqT590/YRnx/49606	intact-crc:B0F99F4E835667A6|rigid:6/futgV6DhTWGv/wADWCfT5Ndw4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q08273	uniprotkb:Q13620	intact:EBI-31686|uniprotkb:D6W1T5|ensemblfungi:YOL133W	intact:EBI-456067|uniprotkb:Q6PIE4|uniprotkb:Q6UP07|uniprotkb:B3KVX4|uniprotkb:B7Z5K8|uniprotkb:Q7Z673|uniprotkb:Q9BY37|uniprotkb:Q9UEB7|uniprotkb:Q9UED7|uniprotkb:B1APK5|ensembl:ENSP00000505084|ensembl:ENSP00000505176|ensembl:ENSP00000506259	psi-mi:rbx1_yeast(display_long)|uniprotkb:E3 ubiquitin-protein ligase complex SCF subunit HRT1(gene name synonym)|uniprotkb:High level expression reduces Ty3 transposition protein 1(gene name synonym)|uniprotkb:HRT1(gene name)|psi-mi:HRT1(display_short)|uniprotkb:RBX1(gene name synonym)|uniprotkb:ROC1(gene name synonym)|uniprotkb:Regulator of cullins protein 1(gene name synonym)|uniprotkb:YOL133W(locus name)	psi-mi:cul4b_human(display_long)|uniprotkb:CUL4B(gene name)|psi-mi:CUL4B(display_short)|uniprotkb:KIAA0695(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11536288|imex:IM-24995-1462	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014508.1|sgd:S000005493|dip:DIP-1373N|mint:Q08273|ensemblfungi:YOL133W(gene)|ensemblfungi:YOL133W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0035361"(Cul8-RING ubiquitin ligase complex)|go:"GO:0051301"(cell division)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097602"(cullin family protein binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR024766|reactome:R-SCE-5696395|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-68949|reactome:R-SCE-8854050|reactome:R-SCE-8951664|reactome:R-SCE-983168|sgd:YOL133W(identity)	refseq:NP_001073341.1|refseq:NP_003579.3|ensembl:ENST00000371322|ensembl:ENSP00000360373|ensembl:ENST00000371323|ensembl:ENSP00000360374|ensembl:ENSP00000505084|ensembl:ENSP00000506259|ensembl:ENSP00000505176|refseq:XP_011529702.1|dip:DIP-31609N|ensembl:ENSG00000158290(gene)|ensembl:ENST00000680673(transcript)|ensembl:ENST00000681253(transcript)|ensembl:ENST00000681652(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031175"(neuron projection development)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031465"(Cul4B-RING E3 ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070914"(UV-damage excision repair)|reactome:R-HSA-5696394|reactome:R-HSA-5696395|reactome:R-HSA-5696400|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-8951664|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR033044|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|mint:Q13620|rcsb pdb:2DO7|rcsb pdb:4A0C|rcsb pdb:4A0L|rcsb pdb:4A64|reactome:R-HSA-110314|entrezgene/locuslink:8450(identity)	-	crc64:A9C3193E48CAF881	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:7LBUfvb6zpWuPkbMDrEAnrMuJj8559292	rogid:D75aMBt3GaBdpBt5Mxsxk7yiRVg9606	intact-crc:9B345ED0BCE7C4C1|rigid:Vra33FHy1ONLghMcrhOtZAGNVTo	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q08273	uniprotkb:O95198	intact:EBI-31686|uniprotkb:D6W1T5|ensemblfungi:YOL133W	intact:EBI-746999|uniprotkb:B2RD18|uniprotkb:Q8N484|uniprotkb:Q8TBH5|uniprotkb:A6NCM7|uniprotkb:B4DFH7|uniprotkb:F5H6M3|ensembl:ENSP00000226725	psi-mi:rbx1_yeast(display_long)|uniprotkb:E3 ubiquitin-protein ligase complex SCF subunit HRT1(gene name synonym)|uniprotkb:High level expression reduces Ty3 transposition protein 1(gene name synonym)|uniprotkb:HRT1(gene name)|psi-mi:HRT1(display_short)|uniprotkb:RBX1(gene name synonym)|uniprotkb:ROC1(gene name synonym)|uniprotkb:Regulator of cullins protein 1(gene name synonym)|uniprotkb:YOL133W(locus name)	psi-mi:klhl2_human(display_long)|uniprotkb:Actin-binding protein Mayven(gene name synonym)|uniprotkb:KLHL2(gene name)|psi-mi:KLHL2(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11536279|imex:IM-24995-1461	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014508.1|sgd:S000005493|dip:DIP-1373N|mint:Q08273|ensemblfungi:YOL133W(gene)|ensemblfungi:YOL133W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0035361"(Cul8-RING ubiquitin ligase complex)|go:"GO:0051301"(cell division)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097602"(cullin family protein binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR024766|reactome:R-SCE-5696395|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-68949|reactome:R-SCE-8854050|reactome:R-SCE-8951664|reactome:R-SCE-983168|sgd:YOL133W(identity)	refseq:NP_001154993.1|refseq:NP_001154994.1|refseq:NP_009177.3|refseq:NP_001317952.1|refseq:NP_001317953.1|refseq:XP_016863165.1|ensembl:ENSG00000109466(gene)|ensembl:ENST00000226725(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030027"(lamellipodium)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR017096(Kelch-like protein, gigaxonin)|interpro:IPR044072|mint:O95198|rcsb pdb:2XN4|rcsb pdb:4CHB|reactome:R-HSA-8951664|reactome:R-HSA-983168|go:"GO:0042802"(identical protein binding)|entrezgene/locuslink:11275(identity)	-	crc64:A9C3193E48CAF881	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:7LBUfvb6zpWuPkbMDrEAnrMuJj8559292	rogid:tFegR2lJZccRqs4qUjdT3PNjNnk9606	intact-crc:CB56B91E17544CFE|rigid:+ylwumnTyxVdpdyc4oGWKo865Bg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UH77	uniprotkb:Q08273	intact:EBI-8524663|uniprotkb:Q9ULU0|uniprotkb:B2RBK7|intact:UNK-6172988|uniprotkb:Q9UH76|uniprotkb:Q9UH75|uniprotkb:Q9Y6V6|ensembl:ENSP00000312397	intact:EBI-31686|uniprotkb:D6W1T5|ensemblfungi:YOL133W	psi-mi:klhl3_human(display_long)|uniprotkb:KLHL3(gene name)|psi-mi:KLHL3(display_short)|uniprotkb:KIAA1129(gene name synonym)	psi-mi:rbx1_yeast(display_long)|uniprotkb:E3 ubiquitin-protein ligase complex SCF subunit HRT1(gene name synonym)|uniprotkb:High level expression reduces Ty3 transposition protein 1(gene name synonym)|uniprotkb:HRT1(gene name)|psi-mi:HRT1(display_short)|uniprotkb:RBX1(gene name synonym)|uniprotkb:ROC1(gene name synonym)|uniprotkb:Regulator of cullins protein 1(gene name synonym)|uniprotkb:YOL133W(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11536297|imex:IM-24995-1463	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_059111.2|refseq:NP_001244124.1|refseq:NP_001244123.1|ensembl:ENSG00000146021(gene)|ensembl:ENST00000309755(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0050801"(ion homeostasis)|go:"GO:0061912"(selective autophagy)|go:"GO:0070294"(renal sodium ion absorption)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0072156"(distal tubule morphogenesis)|go:"GO:0097602"(cullin family protein binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR017096(Kelch-like protein, gigaxonin)|interpro:IPR030578|rcsb pdb:4CH9|rcsb pdb:4HXI|rcsb pdb:5NKP|reactome:R-HSA-8951664|reactome:R-HSA-983168|entrezgene/locuslink:26249(identity)	refseq:NP_014508.1|sgd:S000005493|dip:DIP-1373N|mint:Q08273|ensemblfungi:YOL133W(gene)|ensemblfungi:YOL133W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0035361"(Cul8-RING ubiquitin ligase complex)|go:"GO:0051301"(cell division)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097602"(cullin family protein binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR024766|reactome:R-SCE-5696395|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-68949|reactome:R-SCE-8854050|reactome:R-SCE-8951664|reactome:R-SCE-983168|sgd:YOL133W(identity)	-	comment:mint|comment:homomint|function:Probable substrate-specific adapter of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins	crc64:A9C3193E48CAF881	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:6iZNPY/wNDhLlUWeFLl0FyqtFXM9606	rogid:7LBUfvb6zpWuPkbMDrEAnrMuJj8559292	intact-crc:C2B3C5B2AD1F2ECA|rigid:stfWFAyIC45liOFdXxuWXPy9o8Y	false	sufficient binding region:1-301	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96CD2	uniprotkb:Q08438	intact:EBI-724333|uniprotkb:Q96SX0|ensembl:ENSP00000343190|uniprotkb:Q9HC17	intact:EBI-30482|uniprotkb:O00019|uniprotkb:D6W2B8|ensemblfungi:YOR054C	psi-mi:coac_human(display_long)|uniprotkb:CoaC(gene name synonym)|uniprotkb:PPCDC(gene name)|psi-mi:PPCDC(display_short)|uniprotkb:COAC(gene name synonym)|uniprotkb:MDS018(orf name)|uniprotkb:UNQ9365/PRO34154(orf name)	psi-mi:vhs3_yeast(display_long)|uniprotkb:Viable in a HAL3 SIT4 background protein 3(gene name synonym)|uniprotkb:VHS3(gene name)|psi-mi:VHS3(display_short)|uniprotkb:YOR054C(locus name)|uniprotkb:YOR29-05(orf name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11536308|imex:IM-24995-1464	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_068595.3|rcsb pdb:1QZU|reactome:R-HSA-196783|mint:Q96CD2|ensembl:ENSG00000138621(gene)|ensembl:ENST00000342932(transcript)|go:"GO:0004633"(phosphopantothenoylcysteine decarboxylase activity)|go:"GO:0005829"(cytosol)|go:"GO:0010181"(FMN binding)|go:"GO:0015937"(coenzyme A biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0071513"(phosphopantothenoylcysteine decarboxylase complex)|interpro:IPR003382(Flavoprotein)|interpro:IPR036551|refseq:NP_001288030.1|refseq:NP_001288031.1|refseq:NP_001288032.1|refseq:NP_001288033.1|refseq:NP_001288034.1|entrezgene/locuslink:60490(identity)	refseq:NP_014697.1|sgd:S000005580|dip:DIP-4172N|mint:Q08438|ensemblfungi:YOR054C(gene)|ensemblfungi:YOR054C_mRNA(transcript)|go:"GO:0003824"(catalytic activity)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0007049"(cell cycle)|go:"GO:0010181"(FMN binding)|go:"GO:0015937"(coenzyme A biosynthetic process)|go:"GO:0030004"(cellular monovalent inorganic cation homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0071513"(phosphopantothenoylcysteine decarboxylase complex)|go:"GO:1990143"(CoA-synthesizing protein complex)|interpro:IPR003382(Flavoprotein)|interpro:IPR036551|sgd:YOR054C(identity)	-	-	crc64:A97623473CB6F605	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:2d686R1m4jA5uWpf/8O6rI6/Olo9606	rogid:xBrkL/88mlDFkk10q3ASQnr0rv0559292	intact-crc:E802954B765F11DE|rigid:lDnVx8Qzd0Iw7P3JjS6ee4Lw1FE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P63279	uniprotkb:Q08581	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	intact:EBI-38556|uniprotkb:D6W2Q4|ensemblfungi:YOR195W	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:slk19_yeast(display_long)|uniprotkb:Synthetic lethal KAR3 protein 19(gene name synonym)|uniprotkb:SLK19(gene name)|psi-mi:SLK19(display_short)|uniprotkb:YOR195W(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11536317|imex:IM-24995-1465	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N|entrezgene/locuslink:7329(identity)	sgd:S000005721|refseq:NP_014838.3|mint:Q08581|dip:DIP-2595N|ensemblfungi:YOR195W(gene)|ensemblfungi:YOR195W_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0005819"(spindle)|go:"GO:0005874"(microtubule)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007097"(nuclear migration)|go:"GO:0031536"(positive regulation of exit from mitosis)|go:"GO:0051233"(spindle midzone)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0098653"(centromere clustering)|interpro:IPR024312|sgd:YOR195W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	rogid:3ufBU9ElgshvxT7WluCx2lQX2Rs559292	intact-crc:0F83AE109FF69A84|rigid:siA94kDoSEEwM7+nLStLP0Fb7w8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q08686	uniprotkb:Q92748	intact:EBI-19264|uniprotkb:D6W2V2|ensemblfungi:YOR251C	intact:EBI-1749955|uniprotkb:B2R4W7|ensembl:ENSP00000281030	psi-mi:thtr_yeast(display_long)|uniprotkb:YOR251C(locus name)|uniprotkb:TUM1(gene name)|psi-mi:TUM1(display_short)|uniprotkb:Thiouridine modification protein 1(gene name synonym)	psi-mi:thrsp_human(display_long)|uniprotkb:THRSP(gene name)|psi-mi:THRSP(display_short)|uniprotkb:Spot 14 protein(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11536326|imex:IM-24995-1466	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005777|ensemblfungi:YOR251C(gene)|ensemblfungi:YOR251C_mRNA(transcript)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0002143"(tRNA wobble position uridine thiolation)|go:"GO:0004792"(thiosulfate sulfurtransferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0019346"(transsulfuration)|interpro:IPR001307(Thiosulphate sulphurtransferase, conserved site)|interpro:IPR001763(Rhodanese-like)|interpro:IPR036873|rcsb pdb:3UTN|refseq:NP_014894.3|dip:DIP-4457N|reactome:R-SCE-1614558|sgd:YOR251C(identity)	dip:DIP-40451N|refseq:NP_003242.1|ensembl:ENSG00000151365(gene)|ensembl:ENST00000281030(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0009617"(response to bacterium)|go:"GO:0010866"(regulation of triglyceride biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046890"(regulation of lipid biosynthetic process)|interpro:IPR009786(Thyroid hormone-inducible hepatic Spot 14)|mint:Q92748|reactome:R-HSA-200425|entrezgene/locuslink:7069(identity)	-	crc64:F8082DF7CC279E82	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Hd0nLXm0qNzaqJcSHt/nV73+Pko559292	rogid:tkQQSNiBkUIynoBVT5olWEkCX/o9606	intact-crc:07E29A0C4C776083|rigid:frlWGUDksTUPQXs1A9qSmEDDGYs	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q08909	uniprotkb:O14641	intact:EBI-36654|uniprotkb:D6W378|ensemblfungi:YOR385W	intact:EBI-740850|ensembl:ENSP00000005340|uniprotkb:Q53XM0|uniprotkb:D3DTN3	psi-mi:yo385_yeast(display_long)|uniprotkb:YOR385W(locus name)	psi-mi:dvl2_human(display_long)|uniprotkb:DSH homolog 2(gene name synonym)|uniprotkb:DVL2(gene name)|psi-mi:DVL2(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11536344|imex:IM-24995-1468	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005912|refseq:NP_015030.3|dip:DIP-4047N|ensemblfungi:YOR385W(gene)|ensemblfungi:YOR385W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|sgd:YOR385W(identity)	refseq:NP_004413.1|ensembl:ENSG00000004975(gene)|ensembl:ENST00000005340(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005109"(frizzled binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0007507"(heart development)|go:"GO:0016235"(aggresome)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044340"(canonical Wnt signaling pathway involved in regulation of cell proliferation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0150012"(positive regulation of neuron projection arborization)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008341(Dishevelled-2 region)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:O14641|rcsb pdb:2REY|rcsb pdb:3CBX|rcsb pdb:3CBY|rcsb pdb:3CBZ|rcsb pdb:3CC0|rcsb pdb:4WIP|rcsb pdb:5LNP|rcsb pdb:5SUY|rcsb pdb:5SUZ|rcsb pdb:6IW3|rcsb pdb:6JCK|reactome:R-HSA-201681|reactome:R-HSA-201688|reactome:R-HSA-2028269|reactome:R-HSA-4086400|reactome:R-HSA-4608870|reactome:R-HSA-4641258|reactome:R-HSA-4641262|reactome:R-HSA-5099900|reactome:R-HSA-5368598|reactome:R-HSA-5663220|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9673324|ensembl:ENSP00000005340|dip:DIP-34433N|entrezgene/locuslink:1856(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:8SWTqlDNdzFcWIa8miL9cz87Peg559292	rogid:2Vdc8oRnT4Mz/j+EXQXrL3AszOc9606	intact-crc:7B0FAFE378B3BF04|rigid:jgeiMmVQa2XQYTNFI1203W6IS4w	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P62258	uniprotkb:Q08981	intact:EBI-356498|uniprotkb:P29360|uniprotkb:P42655|uniprotkb:Q53XZ5|uniprotkb:Q63631|uniprotkb:Q7M4R4|uniprotkb:B3KY71|uniprotkb:D3DTH5|uniprotkb:Q4VJB6|ensembl:ENSP00000264335|ensembl:ENSP00000487356	intact:EBI-2345174|uniprotkb:D6W3A3|ensemblfungi:YPL267W	psi-mi:1433e_human(display_long)|uniprotkb:YWHAE(gene name)|psi-mi:YWHAE(display_short)	psi-mi:acm1_yeast(display_long)|uniprotkb:ACM1(gene name)|psi-mi:ACM1(display_short)|uniprotkb:YPL267W(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11536353|imex:IM-24995-1469	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006752.1|dip:DIP-36676N|reactome:R-HSA-1445148|reactome:R-HSA-2028269|reactome:R-HSA-205025|reactome:R-HSA-2565942|reactome:R-HSA-3371453|reactome:R-HSA-3371511|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-75035|reactome:R-HSA-8854518|reactome:R-HSA-8862803|reactome:R-HSA-8876198|ensembl:ENSG00000108953(gene)|ensembl:ENSG00000274474(gene)|ensembl:ENST00000264335(transcript)|ensembl:ENST00000627231(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0003064"(regulation of heart rate by hormone)|go:"GO:0003723"(RNA binding)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005925"(focal adhesion)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050815"(phosphoserine residue binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099072"(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:"GO:1901016"(regulation of potassium ion transmembrane transporter activity)|go:"GO:1901020"(negative regulation of calcium ion transmembrane transporter activity)|go:"GO:1902309"(negative regulation of peptidyl-serine dephosphorylation)|go:"GO:1905913"(negative regulation of calcium ion export across plasma membrane)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P62258|rcsb pdb:2BR9|rcsb pdb:3UAL|rcsb pdb:3UBW|rcsb pdb:6EIH|rcsb pdb:7C8E|reactome:R-HSA-111447|entrezgene/locuslink:7531(identity)	sgd:S000006188|refseq:NP_015056.1|dip:DIP-8871N|mint:Q08981|ensemblfungi:YPL267W(gene)|ensemblfungi:YPL267W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0051301"(cell division)|go:"GO:0055105"(ubiquitin-protein transferase inhibitor activity)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|rcsb pdb:4BH6|sgd:YPL267W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:mnuAjdnQZbMFojll2PnV3xFklXQ9606	rogid:WiRejHsJpiS1aSY3PJUzdRflynM559292	intact-crc:F0FEEEB6BDEA694A|rigid:ilpXeDffZ4W4kHLt6mvDI0gWYeY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q08909	uniprotkb:O00308	intact:EBI-36654|uniprotkb:D6W378|ensemblfungi:YOR385W	intact:EBI-743923|uniprotkb:H3BRF3|uniprotkb:Q6ZTQ5|uniprotkb:A6NEP1|uniprotkb:Q96CZ2|uniprotkb:Q9BWN6|uniprotkb:B2R706|uniprotkb:B4DTL5|uniprotkb:F5H213|uniprotkb:I3RSG8|ensembl:ENSP00000352069	psi-mi:yo385_yeast(display_long)|uniprotkb:YOR385W(locus name)	psi-mi:wwp2_human(display_long)|uniprotkb:WW domain-containing protein 2(gene name synonym)|uniprotkb:Atrophin-1-interacting protein 2(gene name synonym)|uniprotkb:WWP2(gene name)|psi-mi:WWP2(display_short)|uniprotkb:HECT-type E3 ubiquitin transferase WWP2(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11536335|imex:IM-24995-1467	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005912|refseq:NP_015030.3|dip:DIP-4047N|ensemblfungi:YOR385W(gene)|ensemblfungi:YOR385W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|sgd:YOR385W(identity)	refseq:NP_008945.2|refseq:NP_001257383.1|refseq:NP_001257384.1|refseq:XP_011521125.1|refseq:XP_011521127.1|refseq:XP_011521128.1|refseq:NP_001257382.1|refseq:NP_955456.1|refseq:XP_016878368.1|refseq:XP_016878369.1|refseq:XP_016878370.1|ensembl:ENSG00000198373(gene)|ensembl:ENST00000359154(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006858"(extracellular transport)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032410"(negative regulation of transporter activity)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0051224"(negative regulation of protein transport)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:1901016"(regulation of potassium ion transmembrane transporter activity)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000569(HECT)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR024928|interpro:IPR035892|interpro:IPR035983|interpro:IPR036020|mint:O00308|rcsb pdb:4Y07|rcsb pdb:5TJ7|rcsb pdb:5TJ8|rcsb pdb:5TJQ|rcsb pdb:6J1Z|rcsb pdb:6RSS|reactome:R-HSA-8948751|reactome:R-HSA-9013406|reactome:R-HSA-9013409|reactome:R-HSA-9013420|reactome:R-HSA-9013507|entrezgene/locuslink:11060(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:8SWTqlDNdzFcWIa8miL9cz87Peg559292	rogid:Xj0Xssn75HP9sp/tHNe4n83eHPE9606	intact-crc:118148339BACECB6|rigid:GQDfiNCenB5G/dc71iclN6YSxhg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12006	uniprotkb:Q969F0	intact:EBI-36378|uniprotkb:D6W264|ensemblfungi:YOL003C	intact:EBI-743099|ensembl:ENSP00000359375	psi-mi:pfa4_yeast(display_long)|uniprotkb:PFA4(gene name)|psi-mi:PFA4(display_short)|uniprotkb:UNE378(orf name)|uniprotkb:Protein fatty acyltransferase 4(gene name synonym)|uniprotkb:YOL003C(locus name)|uniprotkb:Protein S-acyltransferase(gene name synonym)	psi-mi:fate1_human(display_long)|uniprotkb:Tumor antigen BJ-HCC-2(gene name synonym)|uniprotkb:Cancer/testis antigen 43(gene name synonym)|uniprotkb:FATE1(gene name)|psi-mi:FATE1(display_short)|uniprotkb:FATE(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11536371|imex:IM-24995-1471	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014640.1|sgd:S000005363|dip:DIP-4248N|reactome:R-SCE-203615|ensemblfungi:YOL003C(gene)|ensemblfungi:YOL003C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR033682|sgd:YOL003C(identity)	refseq:NP_149076.1|ensembl:ENSG00000147378(gene)|ensembl:ENST00000370350(transcript)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|go:"GO:0051562"(negative regulation of mitochondrial calcium ion concentration)|interpro:IPR039153|interpro:IPR039433|mint:Q969F0|entrezgene/locuslink:89885(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:yzNswK8Xpbra0kf0p0cRh+CXCqo559292	rogid:Nm1N6lO92MHr5rIKC007oouF5RE9606	intact-crc:CEAB508C51134ECD|rigid:3rCoXocZsVRHENUsM9wJMEg03BE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q10740	uniprotkb:Q8N9N5-2	intact:EBI-10175|uniprotkb:D6W1D4|ensemblfungi:YNL045W	intact:EBI-11524452|ensembl:ENSP00000347125	psi-mi:lkha4_yeast(display_long)|uniprotkb:LAP2(gene name)|psi-mi:LAP2(display_short)|uniprotkb:Epoxide hydrolase(gene name synonym)|uniprotkb:Leucyl aminopeptidase yscIV(gene name synonym)|uniprotkb:Leukotriene A-4 hydrolase homolog(gene name synonym)|uniprotkb:N2535(orf name)|uniprotkb:YNL045W(locus name)	psi-mi:q8n9n5-2(display_long)|uniprotkb:BANP(gene name)|psi-mi:BANP(display_short)|uniprotkb:BEN domain-containing protein 1(gene name synonym)|uniprotkb:BEND1(gene name synonym)|uniprotkb:Btg3-associated nuclear protein(gene name synonym)|uniprotkb:SMAR1(gene name synonym)|uniprotkb:Scaffold/matrix-associated region-1-binding protein(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11536362|imex:IM-24995-1470	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014353.1|sgd:S000004990|go:"GO:0008270"(zinc ion binding)|go:"GO:0030163"(protein catabolic process)|go:"GO:0043171"(peptide catabolic process)|go:"GO:0044255"(cellular lipid metabolic process)|ensemblfungi:YNL045W(gene)|ensemblfungi:YNL045W_mRNA(transcript)|go:"GO:0004177"(aminopeptidase activity)|go:"GO:0004301"(epoxide hydrolase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|interpro:IPR001930(Peptidase M1, membrane alanine aminopeptidase)|go:"GO:0005829"(cytosol)|interpro:IPR012777(Leukotriene A-4 hydrolase/aminopeptidase)|go:"GO:0008237"(metallopeptidase activity)|interpro:IPR014782(Peptidase M1, membrane alanine aminopeptidase, N-terminal)|interpro:IPR015211(Peptidase M1, leukotriene A4 hydrolase, aminopeptidase C-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027268|interpro:IPR034015|interpro:IPR038502|interpro:IPR042097|rcsb pdb:2XPZ|rcsb pdb:2XQ0|reactome:R-SCE-2142691|reactome:R-SCE-6798695|reactome:R-SCE-9018676|reactome:R-SCE-9018681|reactome:R-SCE-9018896|reactome:R-SCE-9020265|rcsb pdb:2XPY|reactome:R-SCE-9023661|dip:DIP-4371N|mint:Q10740|sgd:YNL045W(identity)	ensembl:ENSG00000172530(gene)|ensembl:ENST00000355022(transcript)|intact:EBI-744695(isoform-parent)|uniprotkb:Q8N9N5-2(isoform-parent)|entrezgene/locuslink:54971(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:CqwX8n+boaHaneIOt/jhsAJngF8559292	rogid:ESe6iCAhvq+i57fQHz3rGyg6UOo9606	intact-crc:20746FAFE16E0793|rigid:WO1wZSHxzAEB5Qw2g2FiUe0x0xk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96BA8	uniprotkb:Q12006	intact:EBI-6942903|ensembl:ENSP00000481956|intact:MINT-268046|intact:MINT-8162577|uniprotkb:Q8N2D5|uniprotkb:Q96CP0	intact:EBI-36378|uniprotkb:D6W264|ensemblfungi:YOL003C	psi-mi:cr3l1_human(display_long)|uniprotkb:CREB3L1(gene name)|psi-mi:CREB3L1(display_short)|uniprotkb:OASIS(gene name synonym)|uniprotkb:PSEC0238(orf name)|uniprotkb:Old astrocyte specifically-induced substance(gene name synonym)	psi-mi:pfa4_yeast(display_long)|uniprotkb:PFA4(gene name)|psi-mi:PFA4(display_short)|uniprotkb:UNE378(orf name)|uniprotkb:Protein fatty acyltransferase 4(gene name synonym)|uniprotkb:YOL003C(locus name)|uniprotkb:Protein S-acyltransferase(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11536380|imex:IM-24995-1472	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157613(gene)|ensembl:ENST00000621158(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0070278"(extracellular matrix constituent secretion)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029805|mint:Q96BA8|reactome:R-HSA-8874211|refseq:NP_443086.1|entrezgene/locuslink:90993(identity)	refseq:NP_014640.1|sgd:S000005363|dip:DIP-4248N|reactome:R-SCE-203615|ensemblfungi:YOL003C(gene)|ensemblfungi:YOL003C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR033682|sgd:YOL003C(identity)	-	comment:mint|function:"Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE"	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:sMWUFmBeBBCO+T0Y2CuB/un1lBg9606	rogid:yzNswK8Xpbra0kf0p0cRh+CXCqo559292	intact-crc:99E8B4657288F89E|rigid:j03lKme0dkUdMvCvlrnvcab836E	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12015	uniprotkb:Q9NX47	intact:EBI-31423|uniprotkb:D6W2S8|ensemblfungi:YOR223W	intact:EBI-2341610|ensembl:ENSP00000351813	psi-mi:dsc3_yeast(display_long)|uniprotkb:DSC3(gene name)|psi-mi:DSC3(display_short)|uniprotkb:Defective for SREBP cleavage protein 3(gene name synonym)|uniprotkb:YOR50-13(orf name)|uniprotkb:YOR223W(locus name)	psi-mi:marh5_human(display_long)|uniprotkb:MARCH5(gene name synonym)|uniprotkb:Membrane-associated RING finger protein 5(gene name synonym)|uniprotkb:Membrane-associated RING-CH protein V(gene name synonym)|uniprotkb:Mitochondrial ubiquitin ligase(gene name synonym)|uniprotkb:RING finger protein 153(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase MARCHF5(gene name synonym)|uniprotkb:MARCHF5(gene name)|psi-mi:MARCHF5(display_short)|uniprotkb:RNF153(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11536390|imex:IM-24995-1473	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014866.3|sgd:S000005749|interpro:IPR019413|interpro:IPR025390|ensemblfungi:YOR223W(gene)|ensemblfungi:YOR223W_mRNA(transcript)|go:"GO:0000328"(fungal-type vacuole lumen)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016485"(protein processing)|go:"GO:0044695"(Dsc E3 ubiquitin ligase complex)|sgd:YOR223W(identity)	refseq:NP_060294.1|ensembl:ENSG00000198060(gene)|ensembl:ENST00000358935(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0051020"(GTPase binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070585"(protein localization to mitochondrion)|go:"GO:0090140"(regulation of mitochondrial fission)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0090344"(negative regulation of cell aging)|interpro:IPR011016(Zinc finger, variant RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|mint:Q9NX47|entrezgene/locuslink:54708(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:ebWSvkqYXzLugE3xFfu285Cil8Y559292	rogid:/w+L/oINlKM5ZSm1OkI+R+8PxXg9606	intact-crc:56140741E0BEBF8D|rigid:i4kciKb1mhGdajNeZoHVy8oStDY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12020	uniprotkb:P63279	intact:EBI-38714|uniprotkb:D6VY82|ensemblfungi:YLR082C	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	psi-mi:srl2_yeast(display_long)|uniprotkb:Suppressor of RAD53 null lethality protein 2(gene name synonym)|uniprotkb:SRL2(gene name)|psi-mi:SRL2(display_short)|uniprotkb:YLR082C(locus name)	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11536399|imex:IM-24995-1474	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000004072|refseq:NP_013183.1|mint:Q12020|dip:DIP-1442N|ensemblfungi:YLR082C(gene)|ensemblfungi:YLR082C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006139"(nucleobase-containing compound metabolic process)|sgd:YLR082C(identity)	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N|entrezgene/locuslink:7329(identity)	-	crc64:A39CD3D2E0F9BBF3	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:HVo/JUo9fmmcCD0iLScF47NCDrM559292	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	intact-crc:F8A7872FB1BD181F|rigid:T6PAbjXxLoUlyOa/YM67dr1sJg8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12055	uniprotkb:O95751	intact:EBI-22197|uniprotkb:D6VRI5|uniprotkb:E9P8W4|ensemblfungi:YDL166C	intact:EBI-740738|ensembl:ENSP00000359557|uniprotkb:Q6IAR6	psi-mi:kad6_yeast(display_long)|uniprotkb:FAP7(gene name)|psi-mi:FAP7(display_short)|uniprotkb:POS9-activating factor 7(gene name synonym)|uniprotkb:YDL166C(locus name)|uniprotkb:Dual activity adenylate kinase/ATPase(gene name synonym)	psi-mi:ldoc1_human(display_long)|uniprotkb:Leucine zipper protein down-regulated in cancer cells(gene name synonym)|uniprotkb:LDOC1(gene name)|psi-mi:LDOC1(display_short)|uniprotkb:BCUR1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11536408|imex:IM-24995-1475	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010115.1|sgd:S000002325|reactome:R-SCE-499943|dip:DIP-4793N|ensemblfungi:YDL166C(gene)|ensemblfungi:YDL166C_mRNA(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0004017"(adenylate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0034599"(cellular response to oxidative stress)|interpro:IPR020618|interpro:IPR027417|sgd:YDL166C(identity)	refseq:NP_036449.1|ensembl:ENSG00000182195(gene)|ensembl:ENST00000370526(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071225"(cellular response to muramyl dipeptide)|interpro:IPR032549|interpro:IPR032567|entrezgene/locuslink:23641(identity)	-	crc64:836A25B0D7E2633C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:/hVE29n+kxI3CjMUlxtJxrvUpYk559292	rogid:Ediu0oNiZ/+YVY8l3fNdgP5A+v09606	intact-crc:5A5E8C12F0BAFB19|rigid:ekFS1249aT54NGZSYJuXfSriR8U	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12056	uniprotkb:Q08379	intact:EBI-30488|uniprotkb:D6W2T0|ensemblfungi:YOR226C	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	psi-mi:isu2_yeast(display_long)|uniprotkb:Iron sulfur cluster scaffold protein 2(gene name synonym)|uniprotkb:ISU2(gene name)|psi-mi:ISU2(display_short)|uniprotkb:NUA2(gene name synonym)|uniprotkb:YOR226C(locus name)	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11536439|imex:IM-24995-1478	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005752|refseq:NP_014869.3|dip:DIP-4123N|ensemblfungi:YOR226C(gene)|ensemblfungi:YOR226C_mRNA(transcript)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005737"(cytoplasm)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR002871(NIF system FeS cluster assembly, NifU, N-terminal)|interpro:IPR011339(ISC system FeS cluster assembly, IscU scaffold)|sgd:YOR226C(identity)	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N|entrezgene/locuslink:2801(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2017/05/26	rogid:e4qx7ic8wpO6cTHGl73je/JVzMY559292	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	intact-crc:A899ACCDA1BEDF5C|rigid:s6Eve3irpeAd2PIjh9OxC3n5OJs	false	-	sufficient binding region:383-1002	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8N7W2-2	uniprotkb:Q12055	intact:EBI-10181188|ensembl:ENSP00000367868	intact:EBI-22197|uniprotkb:D6VRI5|uniprotkb:E9P8W4|ensemblfungi:YDL166C	psi-mi:q8n7w2-2(display_long)|uniprotkb:C10orf30(gene name synonym)|uniprotkb:BEND7(gene name)|psi-mi:BEND7(display_short)	psi-mi:kad6_yeast(display_long)|uniprotkb:FAP7(gene name)|psi-mi:FAP7(display_short)|uniprotkb:POS9-activating factor 7(gene name synonym)|uniprotkb:YDL166C(locus name)|uniprotkb:Dual activity adenylate kinase/ATPase(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11536428|imex:IM-24995-1477	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000165626(gene)|ensembl:ENST00000378605(transcript)|intact:EBI-743382(isoform-parent)|uniprotkb:Q8N7W2-2(isoform-parent)|entrezgene/locuslink:222389(identity)	refseq:NP_010115.1|sgd:S000002325|reactome:R-SCE-499943|dip:DIP-4793N|ensemblfungi:YDL166C(gene)|ensemblfungi:YDL166C_mRNA(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0004017"(adenylate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0034599"(cellular response to oxidative stress)|interpro:IPR020618|interpro:IPR027417|sgd:YDL166C(identity)	-	-	crc64:836A25B0D7E2633C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:p6qrTn80hLyVU0W2Tvwn50Q4m5I9606	rogid:/hVE29n+kxI3CjMUlxtJxrvUpYk559292	intact-crc:9204FB32DE7F2471|rigid:tc2fv+VlLxFnsV55ohYeDNQErD8	false	sufficient binding region:10-374	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12055	uniprotkb:Q13164	intact:EBI-22197|uniprotkb:D6VRI5|uniprotkb:E9P8W4|ensemblfungi:YDL166C	intact:EBI-1213983|uniprotkb:Q16634|uniprotkb:Q59F50|uniprotkb:Q6QLU7|uniprotkb:Q7L4P4|uniprotkb:Q969G1|uniprotkb:Q96G51|intact:EBI-28979986|ensembl:ENSP00000311005|ensembl:ENSP00000378966|ensembl:ENSP00000378968	psi-mi:kad6_yeast(display_long)|uniprotkb:FAP7(gene name)|psi-mi:FAP7(display_short)|uniprotkb:POS9-activating factor 7(gene name synonym)|uniprotkb:YDL166C(locus name)|uniprotkb:Dual activity adenylate kinase/ATPase(gene name synonym)	psi-mi:mk07_human(display_long)|uniprotkb:MAPK7(gene name)|psi-mi:MAPK7(display_short)|uniprotkb:BMK1(gene name synonym)|uniprotkb:ERK5(gene name synonym)|uniprotkb:PRKM7(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 5(gene name synonym)|uniprotkb:Big MAP kinase 1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11536417|imex:IM-24995-1476	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010115.1|sgd:S000002325|reactome:R-SCE-499943|dip:DIP-4793N|ensemblfungi:YDL166C(gene)|ensemblfungi:YDL166C_mRNA(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0004017"(adenylate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0034599"(cellular response to oxidative stress)|interpro:IPR020618|interpro:IPR027417|sgd:YDL166C(identity)	refseq:NP_002740.2|refseq:NP_620601.1|refseq:NP_620602.2|refseq:NP_620603.2|ensembl:ENST00000299612|ensembl:ENSP00000299612|ensembl:ENSP00000311005|ensembl:ENSP00000378966|ensembl:ENSP00000378968|refseq:XP_011522259.1|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0036003"(positive regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0051019"(mitogen-activated protein kinase binding)|go:"GO:0051247"(positive regulation of protein metabolic process)|go:"GO:0051344"(negative regulation of cyclic-nucleotide phosphodiesterase activity)|go:"GO:0060761"(negative regulation of response to cytokine stimulus)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071499"(cellular response to laminar fluid shear stress)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1902176"(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:2000352"(negative regulation of endothelial cell apoptotic process)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q13164|rcsb pdb:2Q8Y|rcsb pdb:4B99|rcsb pdb:4IC7|rcsb pdb:4IC8|rcsb pdb:4ZSG|rcsb pdb:4ZSJ|rcsb pdb:4ZSL|rcsb pdb:5BYY|rcsb pdb:5BYZ|rcsb pdb:5O7I|rcsb pdb:6HKM|rcsb pdb:6HKN|reactome:R-HSA-198753|reactome:R-HSA-198765|reactome:R-HSA-202670|reactome:R-HSA-2559582|reactome:R-HSA-881907|reactome:R-HSA-8853659|ensembl:ENSG00000166484(gene)|ensembl:ENST00000308406(transcript)|ensembl:ENST00000395602(transcript)|ensembl:ENST00000395604(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0016605"(PML body)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0030154"(cell differentiation)|go:"GO:0034115"(negative regulation of heterotypic cell-cell adhesion)|entrezgene/locuslink:5598(identity)	-	crc64:836A25B0D7E2633C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:/hVE29n+kxI3CjMUlxtJxrvUpYk559292	rogid:dUTMnlgdjEkFhq0i6RmvpX5U7BM9606	intact-crc:4E6876A8C65AB8A3|rigid:5P8RW0Uuz0dwmHid/nbNPuLrHSQ	false	-	sufficient binding region:140-816	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UJC3	uniprotkb:Q12056	intact:EBI-746704|uniprotkb:O60561|uniprotkb:Q5TG44|uniprotkb:A8MU44|uniprotkb:B4DX15|uniprotkb:A8K8E9|intact:EBI-10969618|ensembl:ENSP00000360252	intact:EBI-30488|uniprotkb:D6W2T0|ensemblfungi:YOR226C	psi-mi:hook1_human(display_long)|uniprotkb:HOOK1(gene name)|psi-mi:HOOK1(display_short)	psi-mi:isu2_yeast(display_long)|uniprotkb:Iron sulfur cluster scaffold protein 2(gene name synonym)|uniprotkb:ISU2(gene name)|psi-mi:ISU2(display_short)|uniprotkb:NUA2(gene name synonym)|uniprotkb:YOR226C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11536468|imex:IM-24995-1481	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_056972.1|ensembl:ENSG00000134709(gene)|ensembl:ENST00000371208(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0007030"(Golgi organization)|go:"GO:0007032"(endosome organization)|go:"GO:0007040"(lysosome organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0015031"(protein transport)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0051959"(dynein light intermediate chain binding)|go:"GO:0070695"(FHF complex)|go:"GO:1905198"(manchette assembly)|go:"GO:1905719"(protein localization to perinuclear region of cytoplasm)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR008636(HOOK)|interpro:IPR036872|interpro:IPR043936|mint:Q9UJC3|entrezgene/locuslink:51361(identity)	sgd:S000005752|refseq:NP_014869.3|dip:DIP-4123N|ensemblfungi:YOR226C(gene)|ensemblfungi:YOR226C_mRNA(transcript)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005737"(cytoplasm)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR002871(NIF system FeS cluster assembly, NifU, N-terminal)|interpro:IPR011339(ISC system FeS cluster assembly, IscU scaffold)|sgd:YOR226C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:QOcYbuKfnNIlNKzos5v+0+A2h3I9606	rogid:e4qx7ic8wpO6cTHGl73je/JVzMY559292	intact-crc:DEF670A9554A88A0|rigid:gr7ksJ1UTUAWMb+nNZCp/sOdtA0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12056	uniprotkb:Q5JR59-3	intact:EBI-30488|uniprotkb:D6W2T0|ensemblfungi:YOR226C	intact:EBI-11522433|ensembl:ENSP00000370186	psi-mi:isu2_yeast(display_long)|uniprotkb:Iron sulfur cluster scaffold protein 2(gene name synonym)|uniprotkb:ISU2(gene name)|psi-mi:ISU2(display_short)|uniprotkb:NUA2(gene name synonym)|uniprotkb:YOR226C(locus name)	psi-mi:q5jr59-3(display_long)|uniprotkb:MTUS2(gene name)|psi-mi:MTUS2(display_short)|uniprotkb:CAZIP(gene name synonym)|uniprotkb:Cardiac zipper protein(gene name synonym)|uniprotkb:KIAA0774(gene name synonym)|uniprotkb:Microtubule plus-end tracking protein TIP150(gene name synonym)|uniprotkb:TIP150(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11536459|imex:IM-24995-1480	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005752|refseq:NP_014869.3|dip:DIP-4123N|ensemblfungi:YOR226C(gene)|ensemblfungi:YOR226C_mRNA(transcript)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005737"(cytoplasm)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR002871(NIF system FeS cluster assembly, NifU, N-terminal)|interpro:IPR011339(ISC system FeS cluster assembly, IscU scaffold)|sgd:YOR226C(identity)	ensembl:ENSG00000132938(gene)|ensembl:ENST00000380808(transcript)|intact:EBI-742948(isoform-parent)|uniprotkb:Q5JR59-3(isoform-parent)|entrezgene/locuslink:23281(identity)	-	-	isoform-comment:No experimental confirmation available.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:e4qx7ic8wpO6cTHGl73je/JVzMY559292	rogid:npId9tC7VoLN/jteoBiRbSYChPs9606	intact-crc:38760D8E0451E300|rigid:ib6N2MWFX4QO5wg3LquH2AFjOl0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P00492	uniprotkb:Q12056	intact:EBI-748210|uniprotkb:A6NHF0|uniprotkb:B2R8M9|ensembl:ENSP00000298556	intact:EBI-30488|uniprotkb:D6W2T0|ensemblfungi:YOR226C	psi-mi:hprt_human(display_long)|uniprotkb:HPRT1(gene name)|psi-mi:HPRT1(display_short)|uniprotkb:HPRT(gene name synonym)	psi-mi:isu2_yeast(display_long)|uniprotkb:Iron sulfur cluster scaffold protein 2(gene name synonym)|uniprotkb:ISU2(gene name)|psi-mi:ISU2(display_short)|uniprotkb:NUA2(gene name synonym)|uniprotkb:YOR226C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11536450|imex:IM-24995-1479	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000185.1|ensembl:ENSG00000165704(gene)|ensembl:ENST00000298556(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001913"(T cell mediated cytotoxicity)|go:"GO:0001975"(response to amphetamine)|go:"GO:0004422"(hypoxanthine phosphoribosyltransferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006164"(purine nucleotide biosynthetic process)|go:"GO:0006166"(purine ribonucleoside salvage)|go:"GO:0006168"(adenine salvage)|go:"GO:0006178"(guanine salvage)|go:"GO:0007625"(grooming behavior)|go:"GO:0007626"(locomotory behavior)|go:"GO:0021756"(striatum development)|go:"GO:0021895"(cerebral cortex neuron differentiation)|go:"GO:0021954"(central nervous system neuron development)|go:"GO:0032263"(GMP salvage)|go:"GO:0032264"(IMP salvage)|go:"GO:0042417"(dopamine metabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043103"(hypoxanthine salvage)|go:"GO:0045964"(positive regulation of dopamine metabolic process)|go:"GO:0046038"(GMP catabolic process)|go:"GO:0046040"(IMP metabolic process)|go:"GO:0046100"(hypoxanthine metabolic process)|go:"GO:0046651"(lymphocyte proliferation)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0052657"(guanine phosphoribosyltransferase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000836(Phosphoribosyltransferase)|interpro:IPR005904(Hypoxanthine phosphoribosyl transferase)|interpro:IPR029057|mint:P00492|rcsb pdb:1BZY|rcsb pdb:1D6N|rcsb pdb:1HMP|rcsb pdb:1Z7G|go:"GO:0048813"(dendrite morphogenesis)|rcsb pdb:2VFA|rcsb pdb:3GEP|rcsb pdb:3GGC|rcsb pdb:3GGJ|rcsb pdb:4IJQ|rcsb pdb:4KN6|rcsb pdb:4RAB|rcsb pdb:4RAC|rcsb pdb:4RAD|rcsb pdb:4RAN|rcsb pdb:4RAO|rcsb pdb:4RAQ|rcsb pdb:5BRN|rcsb pdb:5BSK|rcsb pdb:5HIA|rcsb pdb:5W8V|rcsb pdb:6BNJ|reactome:R-HSA-74217|entrezgene/locuslink:3251(identity)	sgd:S000005752|refseq:NP_014869.3|dip:DIP-4123N|ensemblfungi:YOR226C(gene)|ensemblfungi:YOR226C_mRNA(transcript)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005737"(cytoplasm)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR002871(NIF system FeS cluster assembly, NifU, N-terminal)|interpro:IPR011339(ISC system FeS cluster assembly, IscU scaffold)|sgd:YOR226C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:w87Sv/qOAkHFqJm0vu0Ayqlz7TA9606	rogid:e4qx7ic8wpO6cTHGl73je/JVzMY559292	intact-crc:AF448D8634B1438C|rigid:Lpr9k6sEcTlx/vkByavYO7/5wLg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12056	uniprotkb:Q9UJV3-2	intact:EBI-30488|uniprotkb:D6W2T0|ensemblfungi:YOR226C	intact:EBI-10172526|ensembl:ENSP00000413976	psi-mi:isu2_yeast(display_long)|uniprotkb:Iron sulfur cluster scaffold protein 2(gene name synonym)|uniprotkb:ISU2(gene name)|psi-mi:ISU2(display_short)|uniprotkb:NUA2(gene name synonym)|uniprotkb:YOR226C(locus name)	psi-mi:q9ujv3-2(display_long)|uniprotkb:RING-type E3 ubiquitin transferase MID2(gene name synonym)|uniprotkb:FXY2(gene name synonym)|uniprotkb:Midin-2(gene name synonym)|uniprotkb:Midline defect 2(gene name synonym)|uniprotkb:Midline-2(gene name synonym)|uniprotkb:RING finger protein 60(gene name synonym)|uniprotkb:RNF60(gene name synonym)|uniprotkb:TRIM1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 1(gene name synonym)|uniprotkb:MID2(gene name)|psi-mi:MID2(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11536477|imex:IM-24995-1482	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005752|refseq:NP_014869.3|dip:DIP-4123N|ensemblfungi:YOR226C(gene)|ensemblfungi:YOR226C_mRNA(transcript)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005737"(cytoplasm)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR002871(NIF system FeS cluster assembly, NifU, N-terminal)|interpro:IPR011339(ISC system FeS cluster assembly, IscU scaffold)|sgd:YOR226C(identity)	intact:EBI-751983(isoform-parent)|uniprotkb:Q9UJV3-2(isoform-parent)|ensembl:ENSG00000080561(gene)|ensembl:ENST00000443968(transcript)|entrezgene/locuslink:11043(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:e4qx7ic8wpO6cTHGl73je/JVzMY559292	rogid:/FJ+V2H7SaWon7caUWkEkmHFVxQ9606	intact-crc:924A6D0F4D9EE654|rigid:AvoXwGtX3clmjr6s4MtRim19PzA	false	-	sufficient binding region:21-705	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12071	uniprotkb:Q9H6J7-4	intact:EBI-36751|uniprotkb:D6VS12|ensemblfungi:YDR027C	intact:EBI-11536490|ensembl:ENSP00000367881	psi-mi:vps54_yeast(display_long)|uniprotkb:VPS54(gene name)|psi-mi:VPS54(display_short)|uniprotkb:CGP1(gene name synonym)|uniprotkb:CPF1 genetically-interacting protein 1(gene name synonym)|uniprotkb:Temperature-sensitive clathrin synthetic mutation protein 3(gene name synonym)|uniprotkb:LUV1(gene name synonym)|uniprotkb:RKI1(gene name synonym)|uniprotkb:TCS3(gene name synonym)|uniprotkb:YDR027C(locus name)|uniprotkb:PZF889(orf name)|uniprotkb:YD9813.05C(orf name)	psi-mi:q9h6j7-4(display_long)|uniprotkb:C11orf49(gene name)|psi-mi:C11orf49(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11536488|imex:IM-24995-1483	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010310.1|sgd:S000002434|mint:Q12071|dip:DIP-5903N|ensemblfungi:YDR027C(gene)|ensemblfungi:YDR027C_mRNA(transcript)|go:"GO:0000938"(GARP complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030476"(ascospore wall assembly)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0090156"(cellular sphingolipid homeostasis)|interpro:IPR039745|sgd:YDR027C(identity)	intact:EBI-721300(isoform-parent)|ensembl:ENSG00000149179(gene)|ensembl:ENST00000378618(transcript)|entrezgene/locuslink:79096(identity)	-	-	isoform-comment:No experimental confirmation available.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:zouXMNMGbIJwjId/O7zsCZccY90559292	rogid:IXWzzwfToJyIlZmm7FsAk7WFslY9606	intact-crc:63C262713AB78A77|rigid:QA97QFpcKzHeViAEcPx06mRXIoQ	false	-	sufficient binding region:1-274	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12083	uniprotkb:Q9BRK4	intact:EBI-31634|uniprotkb:D6W3K4|ensemblfungi:YPL164C	intact:EBI-741037|ensembl:ENSP00000359240|ensembl:ENSP00000359243|uniprotkb:Q8N3I0|uniprotkb:Q96J79|uniprotkb:Q96JL2|uniprotkb:B1AL14|uniprotkb:D3DR72	psi-mi:mlh3_yeast(display_long)|uniprotkb:MLH3(gene name)|psi-mi:MLH3(display_short)|uniprotkb:MutL protein homolog 3(gene name synonym)|uniprotkb:P2550(orf name)|uniprotkb:YPL164C(locus name)	psi-mi:lzts2_human(display_long)|uniprotkb:Protein LAPSER1(gene name synonym)|uniprotkb:LZTS2(gene name)|psi-mi:LZTS2(display_short)|uniprotkb:KIAA1813(gene name synonym)|uniprotkb:LAPSER1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11536530|imex:IM-24995-1487	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015161.1|sgd:S000006085|dip:DIP-2414N|ensemblfungi:YPL164C(gene)|ensemblfungi:YPL164C_mRNA(transcript)|go:"GO:0000710"(meiotic mismatch repair)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006298"(mismatch repair)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0030983"(mismatched DNA binding)|go:"GO:0032300"(mismatch repair complex)|go:"GO:0097587"(MutLgamma complex)|interpro:IPR013507(DNA mismatch repair protein, C-terminal)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR014790(MutL, C-terminal, dimerisation)|interpro:IPR020568|interpro:IPR028830|interpro:IPR036890|interpro:IPR037198|interpro:IPR038973|interpro:IPR042120|rcsb pdb:6RMN|rcsb pdb:6SHX|rcsb pdb:6SNS|rcsb pdb:6SNV|sgd:YPL164C(identity)	refseq:NP_115805.1|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030496"(midbody)|go:"GO:0031982"(vesicle)|go:"GO:0051013"(microtubule severing)|go:"GO:0051168"(nuclear export)|go:"GO:0051255"(spindle midzone assembly)|go:"GO:0060682"(primary ureteric bud growth)|go:"GO:0072197"(ureter morphogenesis)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|interpro:IPR028597|mint:Q9BRK4|ensembl:ENSG00000107816(gene)|ensembl:ENST00000370220(transcript)|ensembl:ENST00000370223(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0008285"(negative regulation of cell population proliferation)|refseq:XP_016872269.1|refseq:NP_001305028.1|refseq:NP_001305029.1|refseq:NP_001305030.1|refseq:XP_005270279.1|entrezgene/locuslink:84445(identity)	-	crc64:970FD7F57EB6E3B1	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:g47/5yM9oWZ13CIZOZ7QT6A+LW0559292	rogid:OaMJmnmfm6JniKUJeyg7fS6zRcw9606	intact-crc:244D07CE84D379B2|rigid:tr5QsIWPV4A3k7Sonu0je+Nrc7w	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96CN4	uniprotkb:Q12083	intact:EBI-749523|uniprotkb:B9A6I9|ensembl:ENSP00000270530	intact:EBI-31634|uniprotkb:D6W3K4|ensemblfungi:YPL164C	psi-mi:evi5l_human(display_long)|uniprotkb:Ecotropic viral integration site 5-like protein(gene name synonym)|uniprotkb:EVI5L(gene name)|psi-mi:EVI5L(display_short)	psi-mi:mlh3_yeast(display_long)|uniprotkb:MLH3(gene name)|psi-mi:MLH3(display_short)|uniprotkb:MutL protein homolog 3(gene name synonym)|uniprotkb:P2550(orf name)|uniprotkb:YPL164C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11536521|imex:IM-24995-1486	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153416.1|refseq:NP_660288.1|refseq:XP_005272515.1|refseq:XP_016881728.1|ensembl:ENSG00000142459(gene)|ensembl:ENST00000270530(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0031267"(small GTPase binding)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:1902018"(negative regulation of cilium assembly)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR031214|interpro:IPR035969|entrezgene/locuslink:115704(identity)	refseq:NP_015161.1|sgd:S000006085|dip:DIP-2414N|ensemblfungi:YPL164C(gene)|ensemblfungi:YPL164C_mRNA(transcript)|go:"GO:0000710"(meiotic mismatch repair)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006298"(mismatch repair)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0030983"(mismatched DNA binding)|go:"GO:0032300"(mismatch repair complex)|go:"GO:0097587"(MutLgamma complex)|interpro:IPR013507(DNA mismatch repair protein, C-terminal)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR014790(MutL, C-terminal, dimerisation)|interpro:IPR020568|interpro:IPR028830|interpro:IPR036890|interpro:IPR037198|interpro:IPR038973|interpro:IPR042120|rcsb pdb:6RMN|rcsb pdb:6SHX|rcsb pdb:6SNS|rcsb pdb:6SNV|sgd:YPL164C(identity)	-	-	crc64:970FD7F57EB6E3B1	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:OKfnOqdRupGBmq6gqoeApO0cgG09606	rogid:g47/5yM9oWZ13CIZOZ7QT6A+LW0559292	intact-crc:0734001438E39699|rigid:IqZlr/B4ItdV/mbNSy7C61AoElM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12083	uniprotkb:O14641	intact:EBI-31634|uniprotkb:D6W3K4|ensemblfungi:YPL164C	intact:EBI-740850|ensembl:ENSP00000005340|uniprotkb:Q53XM0|uniprotkb:D3DTN3	psi-mi:mlh3_yeast(display_long)|uniprotkb:MLH3(gene name)|psi-mi:MLH3(display_short)|uniprotkb:MutL protein homolog 3(gene name synonym)|uniprotkb:P2550(orf name)|uniprotkb:YPL164C(locus name)	psi-mi:dvl2_human(display_long)|uniprotkb:DSH homolog 2(gene name synonym)|uniprotkb:DVL2(gene name)|psi-mi:DVL2(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11536512|imex:IM-24995-1485	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015161.1|sgd:S000006085|dip:DIP-2414N|ensemblfungi:YPL164C(gene)|ensemblfungi:YPL164C_mRNA(transcript)|go:"GO:0000710"(meiotic mismatch repair)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006298"(mismatch repair)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0030983"(mismatched DNA binding)|go:"GO:0032300"(mismatch repair complex)|go:"GO:0097587"(MutLgamma complex)|interpro:IPR013507(DNA mismatch repair protein, C-terminal)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR014790(MutL, C-terminal, dimerisation)|interpro:IPR020568|interpro:IPR028830|interpro:IPR036890|interpro:IPR037198|interpro:IPR038973|interpro:IPR042120|rcsb pdb:6RMN|rcsb pdb:6SHX|rcsb pdb:6SNS|rcsb pdb:6SNV|sgd:YPL164C(identity)	refseq:NP_004413.1|ensembl:ENSG00000004975(gene)|ensembl:ENST00000005340(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005109"(frizzled binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0007507"(heart development)|go:"GO:0016235"(aggresome)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044340"(canonical Wnt signaling pathway involved in regulation of cell proliferation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0150012"(positive regulation of neuron projection arborization)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008341(Dishevelled-2 region)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:O14641|rcsb pdb:2REY|rcsb pdb:3CBX|rcsb pdb:3CBY|rcsb pdb:3CBZ|rcsb pdb:3CC0|rcsb pdb:4WIP|rcsb pdb:5LNP|rcsb pdb:5SUY|rcsb pdb:5SUZ|rcsb pdb:6IW3|rcsb pdb:6JCK|reactome:R-HSA-201681|reactome:R-HSA-201688|reactome:R-HSA-2028269|reactome:R-HSA-4086400|reactome:R-HSA-4608870|reactome:R-HSA-4641258|reactome:R-HSA-4641262|reactome:R-HSA-5099900|reactome:R-HSA-5368598|reactome:R-HSA-5663220|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9673324|ensembl:ENSP00000005340|dip:DIP-34433N|entrezgene/locuslink:1856(identity)	-	crc64:970FD7F57EB6E3B1	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:g47/5yM9oWZ13CIZOZ7QT6A+LW0559292	rogid:2Vdc8oRnT4Mz/j+EXQXrL3AszOc9606	intact-crc:B26C58744E6CA680|rigid:16ES/w009LWem2L7ONdWO8+tzbA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96BA8	uniprotkb:Q12078	intact:EBI-6942903|ensembl:ENSP00000481956|intact:MINT-268046|intact:MINT-8162577|uniprotkb:Q8N2D5|uniprotkb:Q96CP0	intact:EBI-37834|uniprotkb:D6VY36|ensemblfungi:YLR034C	psi-mi:cr3l1_human(display_long)|uniprotkb:CREB3L1(gene name)|psi-mi:CREB3L1(display_short)|uniprotkb:OASIS(gene name synonym)|uniprotkb:PSEC0238(orf name)|uniprotkb:Old astrocyte specifically-induced substance(gene name synonym)	psi-mi:smf3_yeast(display_long)|uniprotkb:SMF3(gene name)|psi-mi:SMF3(display_short)|uniprotkb:YLR034C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11536503|imex:IM-24995-1484	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157613(gene)|ensembl:ENST00000621158(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0070278"(extracellular matrix constituent secretion)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029805|mint:Q96BA8|reactome:R-HSA-8874211|refseq:NP_443086.1|entrezgene/locuslink:90993(identity)	refseq:NP_013134.1|sgd:S000004024|dip:DIP-4163N|mint:Q12078|ensemblfungi:YLR034C(gene)|ensemblfungi:YLR034C_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005384"(manganese ion transmembrane transporter activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006826"(iron ion transport)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0015086"(cadmium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022890"(inorganic cation transmembrane transporter activity)|go:"GO:0030026"(cellular manganese ion homeostasis)|go:"GO:0046872"(metal ion binding)|interpro:IPR001046(Natural resistance-associated macrophage protein)|sgd:YLR034C(identity)	-	comment:mint|function:"Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE"	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:sMWUFmBeBBCO+T0Y2CuB/un1lBg9606	rogid:H499EDh2oumEUzbjjW4GvAiVFBo559292	intact-crc:9117DDB4CBADDA1A|rigid:YWJmXxkxAkKRFYGR/c+7lgsFwuo	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12100	uniprotkb:Q9BYV6-2	intact:EBI-36072|uniprotkb:D6VRW6|ensemblfungi:YDL025C	intact:EBI-11522718|ensembl:ENSP00000297348	psi-mi:rtk1_yeast(display_long)|uniprotkb:YDL025C(locus name)|uniprotkb:D2810(orf name)|uniprotkb:RTK1(gene name)|psi-mi:RTK1(display_short)|uniprotkb:Ribosome biogenesis and tRNA synthetase-associated kinase 1(gene name synonym)	psi-mi:q9byv6-2(display_long)|uniprotkb:TRIM55(gene name)|psi-mi:TRIM55(display_short)|uniprotkb:MURF2(gene name synonym)|uniprotkb:Muscle-specific RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 29(gene name synonym)|uniprotkb:RNF29(gene name synonym)|uniprotkb:p50(isoform synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11536539|imex:IM-24995-1488	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010259.1|sgd:S000002183|dip:DIP-6483N|ensemblfungi:YDL025C(gene)|ensemblfungi:YDL025C_mRNA(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0071944"(cell periphery)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|sgd:YDL025C(identity)	intact:EBI-2341179(isoform-parent)|uniprotkb:Q9BYV6-2(isoform-parent)|ensembl:ENSG00000147573(gene)|ensembl:ENST00000353317(transcript)|entrezgene/locuslink:84675(identity)	-	crc64:AD6160F19F3B75CF	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:XBcHXpXSRZDscEoj+hGRn4NJORE559292	rogid:9t8UhK+Z1yBqjnQrOqPD76NuXGg9606	intact-crc:14E1431A64A4C221|rigid:qG6u9WnJpwZk5+NacyJyKRqP1tg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12118	uniprotkb:O95994	intact:EBI-31784|uniprotkb:D6W273|ensemblfungi:YOR007C	intact:EBI-712648|ensembl:ENSP00000391490	psi-mi:sgt2_yeast(display_long)|uniprotkb:Viral protein U-binding protein(gene name synonym)|uniprotkb:SGT/UBP(gene name synonym)|uniprotkb:SGT2(gene name)|psi-mi:SGT2(display_short)|uniprotkb:UNF346(orf name)|uniprotkb:YOR007C(locus name)	psi-mi:agr2_human(display_long)|uniprotkb:Secreted cement gland protein XAG-2 homolog(gene name synonym)|uniprotkb:HPC8(gene name synonym)|uniprotkb:AG2(gene name synonym)|uniprotkb:UNQ515/PRO1030(orf name)|uniprotkb:AGR2(gene name)|psi-mi:AGR2(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11536548|imex:IM-24995-1489	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014649.1|sgd:S000005533|dip:DIP-1983N|mint:Q12118|ensemblfungi:YOR007C(gene)|ensemblfungi:YOR007C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0009408"(response to heat)|go:"GO:0016020"(membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0072380"(TRC complex)|go:"GO:1903646"(positive regulation of chaperone-mediated protein folding)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR032374|rcsb pdb:2LXB|rcsb pdb:2LXC|rcsb pdb:3ZDM|rcsb pdb:4ASV|rcsb pdb:4ASW|rcsb pdb:5LYN|rcsb pdb:5LYP|reactome:R-SCE-9609523|sgd:YOR007C(identity)	go:"GO:0005615"(extracellular space)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0042802"(identical protein binding)|go:"GO:0045742"(positive regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0048546"(digestive tract morphogenesis)|go:"GO:0048639"(positive regulation of developmental growth)|go:"GO:0060480"(lung goblet cell differentiation)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070254"(mucus secretion)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:1903896"(positive regulation of IRE1-mediated unfolded protein response)|go:"GO:1903899"(positive regulation of PERK-mediated unfolded protein response)|interpro:IPR036249|rcsb pdb:2LNS|rcsb pdb:2LNT|ensembl:ENSG00000106541(gene)|ensembl:ENST00000419304(transcript)|go:"GO:0002162"(dystroglycan binding)|go:"GO:0005154"(epidermal growth factor receptor binding)|refseq:NP_006399.1|refseq:XP_005249638.1|dip:DIP-48825N|entrezgene/locuslink:10551(identity)	-	crc64:33539B74F742BD3C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:u4qztYWJIAVQOzZGnkLFnO3S2NA559292	rogid:E824a1MDXuGzk23ohjS7HAeEx5U9606	intact-crc:D80AFBED3FF62FAD|rigid:xaz+7kRyJHFYlSLNGF+ccJsj5sc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O14641	uniprotkb:Q12134	intact:EBI-740850|ensembl:ENSP00000005340|uniprotkb:Q53XM0|uniprotkb:D3DTN3	intact:EBI-37262|uniprotkb:D6W2Y2|ensemblfungi:YOR284W	psi-mi:dvl2_human(display_long)|uniprotkb:DSH homolog 2(gene name synonym)|uniprotkb:DVL2(gene name)|psi-mi:DVL2(display_short)	psi-mi:hua2_yeast(display_long)|uniprotkb:HUA2(gene name)|psi-mi:HUA2(display_short)|uniprotkb:YOR284W(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11536566|imex:IM-24995-1491	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004413.1|ensembl:ENSG00000004975(gene)|ensembl:ENST00000005340(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005109"(frizzled binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0007507"(heart development)|go:"GO:0016235"(aggresome)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044340"(canonical Wnt signaling pathway involved in regulation of cell proliferation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0150012"(positive regulation of neuron projection arborization)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008341(Dishevelled-2 region)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:O14641|rcsb pdb:2REY|rcsb pdb:3CBX|rcsb pdb:3CBY|rcsb pdb:3CBZ|rcsb pdb:3CC0|rcsb pdb:4WIP|rcsb pdb:5LNP|rcsb pdb:5SUY|rcsb pdb:5SUZ|rcsb pdb:6IW3|rcsb pdb:6JCK|reactome:R-HSA-201681|reactome:R-HSA-201688|reactome:R-HSA-2028269|reactome:R-HSA-4086400|reactome:R-HSA-4608870|reactome:R-HSA-4641258|reactome:R-HSA-4641262|reactome:R-HSA-5099900|reactome:R-HSA-5368598|reactome:R-HSA-5663220|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9673324|ensembl:ENSP00000005340|dip:DIP-34433N|entrezgene/locuslink:1856(identity)	sgd:S000005810|refseq:NP_014927.3|dip:DIP-1472N|ensemblfungi:YOR284W(gene)|ensemblfungi:YOR284W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|sgd:YOR284W(identity)	-	-	crc64:B1F3A81B7C0F65AC	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:2Vdc8oRnT4Mz/j+EXQXrL3AszOc9606	rogid:1pZZ+nqYY1Ah7Zdeu4QP4kvKfsw559292	intact-crc:F4F785E1C6C4D062|rigid:5PUN737MJ7ucAP8Bhs3yLOLJQ6M	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8N6L0	uniprotkb:Q12118	intact:EBI-749265|uniprotkb:Q96MC3|ensembl:ENSP00000404220	intact:EBI-31784|uniprotkb:D6W273|ensemblfungi:YOR007C	psi-mi:kash5_human(display_long)|uniprotkb:KASH5(gene name)|psi-mi:KASH5(display_short)|uniprotkb:CCDC155(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 155(gene name synonym)|uniprotkb:KASH domain-containing protein 5(gene name synonym)	psi-mi:sgt2_yeast(display_long)|uniprotkb:Viral protein U-binding protein(gene name synonym)|uniprotkb:SGT/UBP(gene name synonym)|uniprotkb:SGT2(gene name)|psi-mi:SGT2(display_short)|uniprotkb:UNF346(orf name)|uniprotkb:YOR007C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11536557|imex:IM-24995-1490	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_653289.3|ensembl:ENSG00000161609(gene)|ensembl:ENST00000447857(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034397"(telomere localization)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051225"(spindle assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0090172"(microtubule cytoskeleton organization involved in homologous chromosome segregation)|go:"GO:0090220"(chromosome localization to nuclear envelope involved in homologous chromosome segregation)|go:"GO:0090619"(meiotic spindle pole)|interpro:IPR011992(EF-Hand type)|interpro:IPR028168|interpro:IPR028170|interpro:IPR039508|mint:Q8N6L0|rcsb pdb:6R2I|rcsb pdb:6WMF|entrezgene/locuslink:147872(identity)	refseq:NP_014649.1|sgd:S000005533|dip:DIP-1983N|mint:Q12118|ensemblfungi:YOR007C(gene)|ensemblfungi:YOR007C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0009408"(response to heat)|go:"GO:0016020"(membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0072380"(TRC complex)|go:"GO:1903646"(positive regulation of chaperone-mediated protein folding)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR032374|rcsb pdb:2LXB|rcsb pdb:2LXC|rcsb pdb:3ZDM|rcsb pdb:4ASV|rcsb pdb:4ASW|rcsb pdb:5LYN|rcsb pdb:5LYP|reactome:R-SCE-9609523|sgd:YOR007C(identity)	-	-	crc64:33539B74F742BD3C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Wl9L7AcvDHCZuKjYLn8QgGIbZTc9606	rogid:u4qztYWJIAVQOzZGnkLFnO3S2NA559292	intact-crc:757BE1D22B074E42|rigid:oOlfY2RAvw3VKWEdOMZwnytHY8o	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9H190	uniprotkb:Q12134	intact:EBI-742426|ensembl:ENSP00000371233|uniprotkb:O95892|uniprotkb:Q5W0X1|uniprotkb:Q9BZ42|uniprotkb:Q9H567|uniprotkb:Q9NRY8|intact:EBI-28983470|ensembl:ENSP00000342935|ensembl:ENSP00000354013	intact:EBI-37262|uniprotkb:D6W2Y2|ensemblfungi:YOR284W	psi-mi:sdcb2_human(display_long)|uniprotkb:Similar to TACIP18(gene name synonym)|uniprotkb:SDCBP2(gene name)|psi-mi:SDCBP2(display_short)|uniprotkb:SITAC18(gene name synonym)|uniprotkb:Syndecan-binding protein 2(gene name synonym)	psi-mi:hua2_yeast(display_long)|uniprotkb:HUA2(gene name)|psi-mi:HUA2(display_short)|uniprotkb:YOR284W(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11536575|imex:IM-24995-1492	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001186713.1|refseq:NP_056500.2|refseq:NP_536737.3|ensembl:ENSP00000342935|ensembl:ENSP00000354013|ensembl:ENST00000381808|ensembl:ENSP00000371229|ensembl:ENSP00000371233|ensembl:ENSG00000125775(gene)|ensembl:ENST00000360779(transcript)|ensembl:ENST00000381812(transcript)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007399"(nervous system development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016607"(nuclear speck)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046907"(intracellular transport)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036034|interpro:IPR041489|ensembl:ENST00000339987(transcript)|entrezgene/locuslink:27111(identity)	sgd:S000005810|refseq:NP_014927.3|dip:DIP-1472N|ensemblfungi:YOR284W(gene)|ensemblfungi:YOR284W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|sgd:YOR284W(identity)	-	-	crc64:B1F3A81B7C0F65AC	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:vlEtVZkwLTte5PJ4i8ce+SwE/4Y9606	rogid:1pZZ+nqYY1Ah7Zdeu4QP4kvKfsw559292	intact-crc:2EF9424807AA1FC4|rigid:4ghmKfu8fA2mV/jIaTlq1waDxbs	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O15294-3	uniprotkb:Q12140	intact:EBI-11536584|ensembl:ENSP00000362805	intact:EBI-36401|uniprotkb:D6VRV7|ensemblfungi:YDL037C	psi-mi:o15294-3(display_long)|uniprotkb:O-GlcNAc transferase subunit p110(gene name synonym)|uniprotkb:O-linked N-acetylglucosamine transferase 110 kDa subunit(gene name synonym)|uniprotkb:OGT(gene name)|psi-mi:OGT(display_short)	psi-mi:bsc1_yeast(display_long)|uniprotkb:BSC1(gene name)|psi-mi:BSC1(display_short)|uniprotkb:D2734(orf name)|uniprotkb:YDL037C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11536589|imex:IM-24995-1493	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000147162(gene)|ensembl:ENST00000373701(transcript)|intact:EBI-539828(isoform-parent)|uniprotkb:O15294-3(isoform-parent)|entrezgene/locuslink:8473(identity)	sgd:S000002195|refseq:NP_010247.1|mint:Q12140|dip:DIP-5600N|ensemblfungi:YDL037C(gene)|ensemblfungi:YDL037C_mRNA(transcript)|interpro:IPR018789|sgd:YDL037C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:tD46KhQ2nrCEOBxms28dL2gQjFQ9606	rogid:SmUACU6i/VlGLn/aQLehbLRAWjg559292	intact-crc:8EACB0C0DF015FAB|rigid:4/hnLIUJAiygqxxyJvMKyADo424	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12140	uniprotkb:O95994	intact:EBI-36401|uniprotkb:D6VRV7|ensemblfungi:YDL037C	intact:EBI-712648|ensembl:ENSP00000391490	psi-mi:bsc1_yeast(display_long)|uniprotkb:BSC1(gene name)|psi-mi:BSC1(display_short)|uniprotkb:D2734(orf name)|uniprotkb:YDL037C(locus name)	psi-mi:agr2_human(display_long)|uniprotkb:Secreted cement gland protein XAG-2 homolog(gene name synonym)|uniprotkb:HPC8(gene name synonym)|uniprotkb:AG2(gene name synonym)|uniprotkb:UNQ515/PRO1030(orf name)|uniprotkb:AGR2(gene name)|psi-mi:AGR2(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11536598|imex:IM-24995-1494	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002195|refseq:NP_010247.1|mint:Q12140|dip:DIP-5600N|ensemblfungi:YDL037C(gene)|ensemblfungi:YDL037C_mRNA(transcript)|interpro:IPR018789|sgd:YDL037C(identity)	go:"GO:0005615"(extracellular space)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0042802"(identical protein binding)|go:"GO:0045742"(positive regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0048546"(digestive tract morphogenesis)|go:"GO:0048639"(positive regulation of developmental growth)|go:"GO:0060480"(lung goblet cell differentiation)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070254"(mucus secretion)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:1903896"(positive regulation of IRE1-mediated unfolded protein response)|go:"GO:1903899"(positive regulation of PERK-mediated unfolded protein response)|interpro:IPR036249|rcsb pdb:2LNS|rcsb pdb:2LNT|ensembl:ENSG00000106541(gene)|ensembl:ENST00000419304(transcript)|go:"GO:0002162"(dystroglycan binding)|go:"GO:0005154"(epidermal growth factor receptor binding)|refseq:NP_006399.1|refseq:XP_005249638.1|dip:DIP-48825N|entrezgene/locuslink:10551(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:SmUACU6i/VlGLn/aQLehbLRAWjg559292	rogid:E824a1MDXuGzk23ohjS7HAeEx5U9606	intact-crc:FCB4974EFC193C00|rigid:4FQbXEZpmcQEmuFAbCM/QPhhQOs	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12154	uniprotkb:O95994	intact:EBI-2989|uniprotkb:Q6B1B6|uniprotkb:D6VRQ0|ensemblfungi:YDL100C	intact:EBI-712648|ensembl:ENSP00000391490	psi-mi:get3_yeast(display_long)|uniprotkb:YDL100C(locus name)|uniprotkb:GET3(gene name)|psi-mi:GET3(display_short)|uniprotkb:ARR4(gene name synonym)|uniprotkb:D2371(orf name)|uniprotkb:Arsenical pump-driving ATPase(gene name synonym)|uniprotkb:Arsenite-stimulated ATPase(gene name synonym)|uniprotkb:Guided entry of tail-anchored proteins 3(gene name synonym)|uniprotkb:Golgi to ER traffic protein 3(gene name synonym)	psi-mi:agr2_human(display_long)|uniprotkb:Secreted cement gland protein XAG-2 homolog(gene name synonym)|uniprotkb:HPC8(gene name synonym)|uniprotkb:AG2(gene name synonym)|uniprotkb:UNQ515/PRO1030(orf name)|uniprotkb:AGR2(gene name)|psi-mi:AGR2(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11536631|imex:IM-24995-1497	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010183.1|sgd:S000002258|dip:DIP-3908N|mint:Q12154|ensemblfungi:YDL100C(gene)|ensemblfungi:YDL100C_mRNA(transcript)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0009408"(response to heat)|go:"GO:0010038"(response to metal ion)|go:"GO:0016787"(hydrolase activity)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043529"(GET complex)|go:"GO:0045048"(protein insertion into ER membrane)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0046872"(metal ion binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:1990507"(obsolete ATP-independent chaperone mediated protein folding)|interpro:IPR016300(Arsenite-transporting ATPase)|interpro:IPR025723|interpro:IPR027417|interpro:IPR027542|rcsb pdb:2WOJ|rcsb pdb:3A36|rcsb pdb:3A37|rcsb pdb:3B2E|rcsb pdb:3H84|rcsb pdb:3IDQ|rcsb pdb:3SJA|rcsb pdb:3SJB|rcsb pdb:3SJC|rcsb pdb:3SJD|rcsb pdb:3VLC|rcsb pdb:3ZS8|rcsb pdb:3ZS9|rcsb pdb:4PWX|rcsb pdb:4XTR|rcsb pdb:4XVU|rcsb pdb:4XWO|rcsb pdb:5BW8|rcsb pdb:5BWK|sgd:YDL100C(identity)	go:"GO:0005615"(extracellular space)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0042802"(identical protein binding)|go:"GO:0045742"(positive regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0048546"(digestive tract morphogenesis)|go:"GO:0048639"(positive regulation of developmental growth)|go:"GO:0060480"(lung goblet cell differentiation)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070254"(mucus secretion)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:1903896"(positive regulation of IRE1-mediated unfolded protein response)|go:"GO:1903899"(positive regulation of PERK-mediated unfolded protein response)|interpro:IPR036249|rcsb pdb:2LNS|rcsb pdb:2LNT|ensembl:ENSG00000106541(gene)|ensembl:ENST00000419304(transcript)|go:"GO:0002162"(dystroglycan binding)|go:"GO:0005154"(epidermal growth factor receptor binding)|refseq:NP_006399.1|refseq:XP_005249638.1|dip:DIP-48825N|entrezgene/locuslink:10551(identity)	-	crc64:F795C359B5A4A461	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Y+PTDg+beVeCH5mn4BvWi5wBP4A559292	rogid:E824a1MDXuGzk23ohjS7HAeEx5U9606	intact-crc:AA8FCF844134E6BA|rigid:hXSL9mu7GabI1rRK2Hhhykh85Mw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12154	uniprotkb:O95967	intact:EBI-2989|uniprotkb:Q6B1B6|uniprotkb:D6VRQ0|ensemblfungi:YDL100C	intact:EBI-743414|uniprotkb:O75967|uniprotkb:A8K7R4|uniprotkb:B3KM31|uniprotkb:B3KQT1|ensembl:ENSP00000309953|ensembl:ENSP00000435295	psi-mi:get3_yeast(display_long)|uniprotkb:YDL100C(locus name)|uniprotkb:GET3(gene name)|psi-mi:GET3(display_short)|uniprotkb:ARR4(gene name synonym)|uniprotkb:D2371(orf name)|uniprotkb:Arsenical pump-driving ATPase(gene name synonym)|uniprotkb:Arsenite-stimulated ATPase(gene name synonym)|uniprotkb:Guided entry of tail-anchored proteins 3(gene name synonym)|uniprotkb:Golgi to ER traffic protein 3(gene name synonym)	psi-mi:fbln4_human(display_long)|uniprotkb:Fibulin-4(gene name synonym)|uniprotkb:Protein UPH1(gene name synonym)|uniprotkb:EFEMP2(gene name)|psi-mi:EFEMP2(display_short)|uniprotkb:FBLN4(gene name synonym)|uniprotkb:UNQ200/PRO226(orf name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11536622|imex:IM-24995-1496	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010183.1|sgd:S000002258|dip:DIP-3908N|mint:Q12154|ensemblfungi:YDL100C(gene)|ensemblfungi:YDL100C_mRNA(transcript)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0009408"(response to heat)|go:"GO:0010038"(response to metal ion)|go:"GO:0016787"(hydrolase activity)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043529"(GET complex)|go:"GO:0045048"(protein insertion into ER membrane)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0046872"(metal ion binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:1990507"(obsolete ATP-independent chaperone mediated protein folding)|interpro:IPR016300(Arsenite-transporting ATPase)|interpro:IPR025723|interpro:IPR027417|interpro:IPR027542|rcsb pdb:2WOJ|rcsb pdb:3A36|rcsb pdb:3A37|rcsb pdb:3B2E|rcsb pdb:3H84|rcsb pdb:3IDQ|rcsb pdb:3SJA|rcsb pdb:3SJB|rcsb pdb:3SJC|rcsb pdb:3SJD|rcsb pdb:3VLC|rcsb pdb:3ZS8|rcsb pdb:3ZS9|rcsb pdb:4PWX|rcsb pdb:4XTR|rcsb pdb:4XVU|rcsb pdb:4XWO|rcsb pdb:5BW8|rcsb pdb:5BWK|sgd:YDL100C(identity)	refseq:NP_058634.4|ensembl:ENSG00000172638(gene)|ensembl:ENST00000307998(transcript)|ensembl:ENST00000531972(transcript)|go:"GO:0001527"(microfibril)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0008201"(heparin binding)|go:"GO:0031012"(extracellular matrix)|go:"GO:0035904"(aorta development)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0048251"(elastic fiber assembly)|go:"GO:0060414"(aorta smooth muscle tissue morphogenesis)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071953"(elastic fiber)|go:"GO:0097084"(vascular associated smooth muscle cell development)|go:"GO:1903561"(extracellular vesicle)|go:"GO:1904026"(regulation of collagen fibril organization)|go:"GO:1904028"(positive regulation of collagen fibril organization)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1904831"(positive regulation of aortic smooth muscle cell differentiation)|go:"GO:1905609"(positive regulation of smooth muscle cell-matrix adhesion)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR018097|interpro:IPR026823|interpro:IPR026824|mint:O95967|rcsb pdb:2KL7|reactome:R-HSA-2129379|dip:DIP-34518N|entrezgene/locuslink:30008(identity)	-	crc64:F795C359B5A4A461	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Y+PTDg+beVeCH5mn4BvWi5wBP4A559292	rogid:L8jMp8rFYb6DRRusfWgyd9zN2KI9606	intact-crc:C63540E87CF05A1D|rigid:/akFsFjlNJyDpjpxsyG/tWm3cig	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O43852-3	uniprotkb:Q12154	intact:EBI-11536607|ensembl:ENSP00000420381	intact:EBI-2989|uniprotkb:Q6B1B6|uniprotkb:D6VRQ0|ensemblfungi:YDL100C	psi-mi:o43852-3(display_long)|uniprotkb:CALU(gene name)|psi-mi:CALU(display_short)|uniprotkb:Crocalbin(gene name synonym)|uniprotkb:IEF SSP 9302(gene name synonym)	psi-mi:get3_yeast(display_long)|uniprotkb:YDL100C(locus name)|uniprotkb:GET3(gene name)|psi-mi:GET3(display_short)|uniprotkb:ARR4(gene name synonym)|uniprotkb:D2371(orf name)|uniprotkb:Arsenical pump-driving ATPase(gene name synonym)|uniprotkb:Arsenite-stimulated ATPase(gene name synonym)|uniprotkb:Guided entry of tail-anchored proteins 3(gene name synonym)|uniprotkb:Golgi to ER traffic protein 3(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11536611|imex:IM-24995-1495	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-1171069(isoform-parent)|ensembl:ENSG00000128595(gene)|ensembl:ENST00000479257(transcript)|uniprotkb:O43852-3(isoform-parent)|entrezgene/locuslink:813(identity)	refseq:NP_010183.1|sgd:S000002258|dip:DIP-3908N|mint:Q12154|ensemblfungi:YDL100C(gene)|ensemblfungi:YDL100C_mRNA(transcript)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0009408"(response to heat)|go:"GO:0010038"(response to metal ion)|go:"GO:0016787"(hydrolase activity)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043529"(GET complex)|go:"GO:0045048"(protein insertion into ER membrane)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0046872"(metal ion binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:1990507"(obsolete ATP-independent chaperone mediated protein folding)|interpro:IPR016300(Arsenite-transporting ATPase)|interpro:IPR025723|interpro:IPR027417|interpro:IPR027542|rcsb pdb:2WOJ|rcsb pdb:3A36|rcsb pdb:3A37|rcsb pdb:3B2E|rcsb pdb:3H84|rcsb pdb:3IDQ|rcsb pdb:3SJA|rcsb pdb:3SJB|rcsb pdb:3SJC|rcsb pdb:3SJD|rcsb pdb:3VLC|rcsb pdb:3ZS8|rcsb pdb:3ZS9|rcsb pdb:4PWX|rcsb pdb:4XTR|rcsb pdb:4XVU|rcsb pdb:4XWO|rcsb pdb:5BW8|rcsb pdb:5BWK|sgd:YDL100C(identity)	-	-	crc64:F795C359B5A4A461	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:aOndJVrdQPKMOgVAthD1hiWG67I9606	rogid:Y+PTDg+beVeCH5mn4BvWi5wBP4A559292	intact-crc:5150A6ED78AAE03B|rigid:GvPIIbD+WC8wfweB85M2uc9EhGA	false	sufficient binding region:9-323	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12156	uniprotkb:Q13164	intact:EBI-30371|uniprotkb:D6VS49|ensemblfungi:YDR063W	intact:EBI-1213983|uniprotkb:Q16634|uniprotkb:Q59F50|uniprotkb:Q6QLU7|uniprotkb:Q7L4P4|uniprotkb:Q969G1|uniprotkb:Q96G51|intact:EBI-28979986|ensembl:ENSP00000311005|ensembl:ENSP00000378966|ensembl:ENSP00000378968	psi-mi:aim7_yeast(display_long)|uniprotkb:AIM7(gene name)|psi-mi:AIM7(display_short)|uniprotkb:D4245(orf name)|uniprotkb:YDR063W(locus name)|uniprotkb:Altered inheritance rate of mitochondria protein 7(gene name synonym)	psi-mi:mk07_human(display_long)|uniprotkb:MAPK7(gene name)|psi-mi:MAPK7(display_short)|uniprotkb:BMK1(gene name synonym)|uniprotkb:ERK5(gene name synonym)|uniprotkb:PRKM7(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 5(gene name synonym)|uniprotkb:Big MAP kinase 1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11536655|imex:IM-24995-1499	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010348.1|sgd:S000002470|dip:DIP-1818N|mint:Q12156|ensemblfungi:YDR063W(gene)|ensemblfungi:YDR063W_mRNA(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0030479"(actin cortical patch)|go:"GO:0034316"(negative regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0071846"(actin filament debranching)|go:"GO:0071933"(Arp2/3 complex binding)|interpro:IPR002108(Actin-binding, cofilin/tropomyosin type)|interpro:IPR011171(Glia maturation factor beta)|interpro:IPR029006|reactome:R-SCE-6798695|sgd:YDR063W(identity)	refseq:NP_002740.2|refseq:NP_620601.1|refseq:NP_620602.2|refseq:NP_620603.2|ensembl:ENST00000299612|ensembl:ENSP00000299612|ensembl:ENSP00000311005|ensembl:ENSP00000378966|ensembl:ENSP00000378968|refseq:XP_011522259.1|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0036003"(positive regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0051019"(mitogen-activated protein kinase binding)|go:"GO:0051247"(positive regulation of protein metabolic process)|go:"GO:0051344"(negative regulation of cyclic-nucleotide phosphodiesterase activity)|go:"GO:0060761"(negative regulation of response to cytokine stimulus)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071499"(cellular response to laminar fluid shear stress)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1902176"(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:2000352"(negative regulation of endothelial cell apoptotic process)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q13164|rcsb pdb:2Q8Y|rcsb pdb:4B99|rcsb pdb:4IC7|rcsb pdb:4IC8|rcsb pdb:4ZSG|rcsb pdb:4ZSJ|rcsb pdb:4ZSL|rcsb pdb:5BYY|rcsb pdb:5BYZ|rcsb pdb:5O7I|rcsb pdb:6HKM|rcsb pdb:6HKN|reactome:R-HSA-198753|reactome:R-HSA-198765|reactome:R-HSA-202670|reactome:R-HSA-2559582|reactome:R-HSA-881907|reactome:R-HSA-8853659|ensembl:ENSG00000166484(gene)|ensembl:ENST00000308406(transcript)|ensembl:ENST00000395602(transcript)|ensembl:ENST00000395604(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0016605"(PML body)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0030154"(cell differentiation)|go:"GO:0034115"(negative regulation of heterotypic cell-cell adhesion)|entrezgene/locuslink:5598(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:gNpFPaIObSMCgvbNabMJOjJMjco559292	rogid:dUTMnlgdjEkFhq0i6RmvpX5U7BM9606	intact-crc:9B98BCA8AC013590|rigid:u53oTcdp6xI5CMxJ6KZDXnSo5HE	false	-	sufficient binding region:140-816	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12154	uniprotkb:Q9BXJ1-2	intact:EBI-2989|uniprotkb:Q6B1B6|uniprotkb:D6VRQ0|ensemblfungi:YDL100C	intact:EBI-11536642	psi-mi:get3_yeast(display_long)|uniprotkb:YDL100C(locus name)|uniprotkb:GET3(gene name)|psi-mi:GET3(display_short)|uniprotkb:ARR4(gene name synonym)|uniprotkb:D2371(orf name)|uniprotkb:Arsenical pump-driving ATPase(gene name synonym)|uniprotkb:Arsenite-stimulated ATPase(gene name synonym)|uniprotkb:Guided entry of tail-anchored proteins 3(gene name synonym)|uniprotkb:Golgi to ER traffic protein 3(gene name synonym)	psi-mi:q9bxj1-2(display_long)|uniprotkb:CTRP1(gene name synonym)|uniprotkb:G protein-coupled receptor-interacting protein(gene name synonym)|uniprotkb:UNQ310/PRO353(orf name)|uniprotkb:C1QTNF1(gene name)|psi-mi:C1QTNF1(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11536640|imex:IM-24995-1498	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010183.1|sgd:S000002258|dip:DIP-3908N|mint:Q12154|ensemblfungi:YDL100C(gene)|ensemblfungi:YDL100C_mRNA(transcript)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0009408"(response to heat)|go:"GO:0010038"(response to metal ion)|go:"GO:0016787"(hydrolase activity)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043529"(GET complex)|go:"GO:0045048"(protein insertion into ER membrane)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0046872"(metal ion binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:1990507"(obsolete ATP-independent chaperone mediated protein folding)|interpro:IPR016300(Arsenite-transporting ATPase)|interpro:IPR025723|interpro:IPR027417|interpro:IPR027542|rcsb pdb:2WOJ|rcsb pdb:3A36|rcsb pdb:3A37|rcsb pdb:3B2E|rcsb pdb:3H84|rcsb pdb:3IDQ|rcsb pdb:3SJA|rcsb pdb:3SJB|rcsb pdb:3SJC|rcsb pdb:3SJD|rcsb pdb:3VLC|rcsb pdb:3ZS8|rcsb pdb:3ZS9|rcsb pdb:4PWX|rcsb pdb:4XTR|rcsb pdb:4XVU|rcsb pdb:4XWO|rcsb pdb:5BW8|rcsb pdb:5BWK|sgd:YDL100C(identity)	intact:EBI-750200(isoform-parent)|uniprotkb:Q9BXJ1-2(isoform-parent)|entrezgene/locuslink:114897(identity)	-	crc64:F795C359B5A4A461	isoform-comment:No experimental confirmation available.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Y+PTDg+beVeCH5mn4BvWi5wBP4A559292	rogid:zxCXWIEWsl8hYnOP6DlBiu0oiNw9606	intact-crc:53764ECF7B633966|rigid:eVXYasvZvmyJ90iVGaxTTZv/h60	false	-	sufficient binding region:11-291	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:E9PFK9	uniprotkb:Q12161	intact:EBI-11523104|ensembl:ENSP00000403429	intact:EBI-34372|uniprotkb:D6W213|ensemblfungi:YOL054W	psi-mi:e9pfk9_human(display_long)|uniprotkb:RABGEF1(gene name)|psi-mi:RABGEF1(display_short)	psi-mi:psh1_yeast(display_long)|uniprotkb:PSH1(gene name)|psi-mi:PSH1(display_short)|uniprotkb:POB3/SPT16 histone-associated protein 1(gene name synonym)|uniprotkb:O1263(orf name)|uniprotkb:YOL054W(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11536675|imex:IM-24995-1501	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000154710(gene)|ensembl:ENST00000439720(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|interpro:IPR002653(Zinc finger, A20-type)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR037191|interpro:IPR041545|entrezgene/locuslink:27342(identity)	refseq:NP_014587.1|sgd:S000005415|mint:Q12161|dip:DIP-6481N|ensemblfungi:YOL054W(gene)|ensemblfungi:YOL054W_mRNA(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|sgd:YOL054W(identity)	-	-	crc64:CE0ECBCB6D465554	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:JDHW8cuCB2z39j6a+LlkARnLfYo9606	rogid:AvPMRd/GjfaTyQjEfMPhBVcvOs4559292	intact-crc:97C0F66AD645E4B2|rigid:TsRHWiVq3l/wIp27zh63pFUpDhc	false	sufficient binding region:14-504	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12161	uniprotkb:P15622-3	intact:EBI-34372|uniprotkb:D6W213|ensemblfungi:YOL054W	intact:EBI-10177272|ensembl:ENSP00000393442	psi-mi:psh1_yeast(display_long)|uniprotkb:PSH1(gene name)|psi-mi:PSH1(display_short)|uniprotkb:POB3/SPT16 histone-associated protein 1(gene name synonym)|uniprotkb:O1263(orf name)|uniprotkb:YOL054W(locus name)	psi-mi:p15622-3(display_long)|uniprotkb:ZNF647(gene name synonym)|uniprotkb:Zinc finger protein 647(gene name synonym)|uniprotkb:ZNF250(gene name)|psi-mi:ZNF250(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11536686|imex:IM-24995-1502	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014587.1|sgd:S000005415|mint:Q12161|dip:DIP-6481N|ensemblfungi:YOL054W(gene)|ensemblfungi:YOL054W_mRNA(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|sgd:YOL054W(identity)	ensembl:ENSG00000196150(gene)|ensembl:ENST00000417550(transcript)|intact:EBI-739678(isoform-parent)|uniprotkb:P15622-3(isoform-parent)|entrezgene/locuslink:58500(identity)	-	crc64:CE0ECBCB6D465554	isoform-comment:No experimental confirmation available.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:AvPMRd/GjfaTyQjEfMPhBVcvOs4559292	rogid:4AVjeOREEATULMJWtdeZt7rhi889606	intact-crc:358C2456B9479219|rigid:yRJou5+PcnSKbx49lLrit7cH2y0	false	-	sufficient binding region:46-555	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12161	uniprotkb:Q8N5R6	intact:EBI-34372|uniprotkb:D6W213|ensemblfungi:YOL054W	intact:EBI-740841|intact:EBI-953781|uniprotkb:B3KQ49|uniprotkb:A8K3U4|uniprotkb:A8MPQ6|uniprotkb:A8MV61|uniprotkb:A8MVU9|uniprotkb:Q9H5Q6|uniprotkb:Q8TAX6|intact:EBI-2320546|intact:EBI-11522976	psi-mi:psh1_yeast(display_long)|uniprotkb:PSH1(gene name)|psi-mi:PSH1(display_short)|uniprotkb:POB3/SPT16 histone-associated protein 1(gene name synonym)|uniprotkb:O1263(orf name)|uniprotkb:YOL054W(locus name)	psi-mi:ccd33_human(display_long)|uniprotkb:CCDC33(gene name)|psi-mi:CCDC33(display_short)|uniprotkb:Cancer/testis antigen 61(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11536666|imex:IM-24995-1500	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014587.1|sgd:S000005415|mint:Q12161|dip:DIP-6481N|ensemblfungi:YOL054W(gene)|ensemblfungi:YOL054W_mRNA(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|sgd:YOL054W(identity)	refseq:NP_079331.3|interpro:IPR000008(C2 calcium-dependent membrane targeting)|go:"GO:0005777"(peroxisome)|refseq:NP_001274110.1|refseq:NP_877592.2|mint:Q8N5R6|interpro:IPR035892|interpro:IPR039889|entrezgene/locuslink:80125(identity)	-	crc64:CE0ECBCB6D465554	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2021/11/30	rogid:AvPMRd/GjfaTyQjEfMPhBVcvOs4559292	rogid:eEIn7pQyfdHWx8TeLJpYy0i/gww9606	intact-crc:595331217654ABEE|rigid:aXopAJOgoLUSDTx6zmifwQ79GHA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12161	uniprotkb:P23511-2	intact:EBI-34372|uniprotkb:D6W213|ensemblfungi:YOL054W	intact:EBI-11061759|ensembl:ENSP00000229418	psi-mi:psh1_yeast(display_long)|uniprotkb:PSH1(gene name)|psi-mi:PSH1(display_short)|uniprotkb:POB3/SPT16 histone-associated protein 1(gene name synonym)|uniprotkb:O1263(orf name)|uniprotkb:YOL054W(locus name)	psi-mi:p23511-2(display_long)|uniprotkb:NFYA(gene name)|psi-mi:NFYA(display_short)|uniprotkb:CAAT box DNA-binding protein subunit A(gene name synonym)|uniprotkb:Nuclear transcription factor Y subunit A(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11536698|imex:IM-24995-1503	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014587.1|sgd:S000005415|mint:Q12161|dip:DIP-6481N|ensemblfungi:YOL054W(gene)|ensemblfungi:YOL054W_mRNA(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|sgd:YOL054W(identity)	intact:EBI-389739(isoform-parent)|ensembl:ENSG00000001167(gene)|ensembl:ENST00000353205(transcript)|uniprotkb:P23511-2(isoform-parent)|entrezgene/locuslink:4800(identity)	-	crc64:CE0ECBCB6D465554	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:AvPMRd/GjfaTyQjEfMPhBVcvOs4559292	rogid:9IOUoaGszX6kd9hzrCj6BBkgJ+09606	intact-crc:555C4D546DB74428|rigid:DUrLoLDtg9vUEdl/j7cl4a61p34	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96Q35-2	uniprotkb:Q12161	intact:EBI-11533409|ensembl:ENSP00000376086|ensembl:ENSP00000412073	intact:EBI-34372|uniprotkb:D6W213|ensemblfungi:YOL054W	psi-mi:q96q35-2(display_long)|uniprotkb:FLACC1(gene name)|psi-mi:FLACC1(display_short)|uniprotkb:ALS2CR12(gene name synonym)|uniprotkb:Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 12 protein(gene name synonym)	psi-mi:psh1_yeast(display_long)|uniprotkb:PSH1(gene name)|psi-mi:PSH1(display_short)|uniprotkb:POB3/SPT16 histone-associated protein 1(gene name synonym)|uniprotkb:O1263(orf name)|uniprotkb:YOL054W(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11536765|imex:IM-24995-1510	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-750451(isoform-parent)|uniprotkb:Q96Q35-2(isoform-parent)|ensembl:ENSG00000155749(gene)|ensembl:ENST00000392257(transcript)|ensembl:ENST00000439709(transcript)|entrezgene/locuslink:130540(identity)	refseq:NP_014587.1|sgd:S000005415|mint:Q12161|dip:DIP-6481N|ensemblfungi:YOL054W(gene)|ensemblfungi:YOL054W_mRNA(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|sgd:YOL054W(identity)	-	isoform-comment:No experimental confirmation available.	crc64:CE0ECBCB6D465554	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:bdqsMHSGebh2qVAwEO8DhTbZOHM9606	rogid:AvPMRd/GjfaTyQjEfMPhBVcvOs4559292	intact-crc:FD1719BA3A1DEA49|rigid:9Lw5c07SoW0m9ntpxDUfHEqxDkQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q969J2	uniprotkb:Q12161	intact:EBI-2818641|uniprotkb:B2RE32|uniprotkb:Q5U7L4|intact:EBI-28979011|ensembl:ENSP00000366509	intact:EBI-34372|uniprotkb:D6W213|ensemblfungi:YOL054W	psi-mi:zksc4_human(display_long)|uniprotkb:ZKSCAN4(gene name)|psi-mi:ZKSCAN4(display_short)|uniprotkb:ZNF307(gene name synonym)|uniprotkb:ZNF427(gene name synonym)|uniprotkb:P373c6.1(gene name synonym)|uniprotkb:Zinc finger protein 307(gene name synonym)|uniprotkb:Zinc finger protein 427(gene name synonym)	psi-mi:psh1_yeast(display_long)|uniprotkb:PSH1(gene name)|psi-mi:PSH1(display_short)|uniprotkb:POB3/SPT16 histone-associated protein 1(gene name synonym)|uniprotkb:O1263(orf name)|uniprotkb:YOL054W(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11536756|imex:IM-24995-1509	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_061983.2|ensembl:ENSP00000366509|ensembl:ENSG00000187626(gene)|ensembl:ENST00000377294(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|interpro:IPR038269|mint:Q969J2|reactome:R-HSA-212436|refseq:XP_005249152.1|entrezgene/locuslink:387032(identity)	refseq:NP_014587.1|sgd:S000005415|mint:Q12161|dip:DIP-6481N|ensemblfungi:YOL054W(gene)|ensemblfungi:YOL054W_mRNA(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|sgd:YOL054W(identity)	-	-	crc64:CE0ECBCB6D465554	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:5TWhAtzfmCXHkOSbjKwjgLIsCcs9606	rogid:AvPMRd/GjfaTyQjEfMPhBVcvOs4559292	intact-crc:2A7AC0D15D10BC94|rigid:WiqvZDzvfklS89IxQr5U6KY8I3U	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8WTR7	uniprotkb:Q12161	intact:EBI-751409|uniprotkb:Q9ULS9|uniprotkb:Q9Y4Q7|uniprotkb:A8K8T7|intact:EBI-28978826|ensembl:ENSP00000270617|ensembl:ENSP00000375697|ensembl:ENSP00000472808	intact:EBI-34372|uniprotkb:D6W213|ensemblfungi:YOL054W	psi-mi:zn473_human(display_long)|uniprotkb:Zinc finger protein 100 homolog(gene name synonym)|uniprotkb:ZNF473(gene name)|psi-mi:ZNF473(display_short)|uniprotkb:KIAA1141(gene name synonym)|uniprotkb:ZFP100(gene name synonym)	psi-mi:psh1_yeast(display_long)|uniprotkb:PSH1(gene name)|psi-mi:PSH1(display_short)|uniprotkb:POB3/SPT16 histone-associated protein 1(gene name synonym)|uniprotkb:O1263(orf name)|uniprotkb:YOL054W(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11536747|imex:IM-24995-1508	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001006657.1|refseq:NP_056243.1|ensembl:ENSP00000270617|ensembl:ENSP00000375697|ensembl:ENSP00000472808|refseq:NP_001295353.1|ensembl:ENSG00000142528(gene)|ensembl:ENST00000270617(transcript)|ensembl:ENST00000391821(transcript)|ensembl:ENST00000595661(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006398"(mRNA 3'-end processing by stem-loop binding and cleavage)|go:"GO:0015030"(Cajal body)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|rcsb pdb:2EMB|rcsb pdb:2EMC|rcsb pdb:2EME|rcsb pdb:2EOU|rcsb pdb:2EOX|rcsb pdb:2EOY|rcsb pdb:2EOZ|rcsb pdb:2YRH|rcsb pdb:2YRJ|rcsb pdb:2YSV|rcsb pdb:2YTD|rcsb pdb:2YTE|rcsb pdb:2YTT|rcsb pdb:2YU5|reactome:R-HSA-111367|reactome:R-HSA-212436|reactome:R-HSA-73856|reactome:R-HSA-77588|entrezgene/locuslink:25888(identity)	refseq:NP_014587.1|sgd:S000005415|mint:Q12161|dip:DIP-6481N|ensemblfungi:YOL054W(gene)|ensemblfungi:YOL054W_mRNA(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|sgd:YOL054W(identity)	-	-	crc64:CE0ECBCB6D465554	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Tm+mqhJ8JVqLYFprsek+VYhcnOI9606	rogid:AvPMRd/GjfaTyQjEfMPhBVcvOs4559292	intact-crc:2AEDDBE9A0A1A14D|rigid:9TdmBK0UL0UE5I8qwhuByTvAazU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8N7W2-2	uniprotkb:Q12161	intact:EBI-10181188|ensembl:ENSP00000367868	intact:EBI-34372|uniprotkb:D6W213|ensemblfungi:YOL054W	psi-mi:q8n7w2-2(display_long)|uniprotkb:C10orf30(gene name synonym)|uniprotkb:BEND7(gene name)|psi-mi:BEND7(display_short)	psi-mi:psh1_yeast(display_long)|uniprotkb:PSH1(gene name)|psi-mi:PSH1(display_short)|uniprotkb:POB3/SPT16 histone-associated protein 1(gene name synonym)|uniprotkb:O1263(orf name)|uniprotkb:YOL054W(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11536736|imex:IM-24995-1507	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000165626(gene)|ensembl:ENST00000378605(transcript)|intact:EBI-743382(isoform-parent)|uniprotkb:Q8N7W2-2(isoform-parent)|entrezgene/locuslink:222389(identity)	refseq:NP_014587.1|sgd:S000005415|mint:Q12161|dip:DIP-6481N|ensemblfungi:YOL054W(gene)|ensemblfungi:YOL054W_mRNA(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|sgd:YOL054W(identity)	-	-	crc64:CE0ECBCB6D465554	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:p6qrTn80hLyVU0W2Tvwn50Q4m5I9606	rogid:AvPMRd/GjfaTyQjEfMPhBVcvOs4559292	intact-crc:831A478232ACC6A4|rigid:KM2IIjxphzbMyRqwAMNC5CTyd7g	false	sufficient binding region:10-374	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q7L190	uniprotkb:Q12161	intact:EBI-710457|intact:EBI-28975079|ensembl:ENSP00000335306|uniprotkb:Q9H9N5|uniprotkb:Q9NVI6|uniprotkb:A8K4M7	intact:EBI-34372|uniprotkb:D6W213|ensemblfungi:YOL054W	psi-mi:dppa4_human(display_long)|uniprotkb:DPPA4(gene name)|psi-mi:DPPA4(display_short)	psi-mi:psh1_yeast(display_long)|uniprotkb:PSH1(gene name)|psi-mi:PSH1(display_short)|uniprotkb:POB3/SPT16 histone-associated protein 1(gene name synonym)|uniprotkb:O1263(orf name)|uniprotkb:YOL054W(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11536725|imex:IM-24995-1506	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060659.3|mint:Q7L190|reactome:R-HSA-2892247|ensembl:ENSG00000121570(gene)|ensembl:ENST00000335658(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0048731"(system development)|go:"GO:0060484"(lung-associated mesenchyme development)|interpro:IPR025891|interpro:IPR025892|interpro:IPR039590|interpro:IPR039836|ensembl:ENSP00000335306|entrezgene/locuslink:55211(identity)	refseq:NP_014587.1|sgd:S000005415|mint:Q12161|dip:DIP-6481N|ensemblfungi:YOL054W(gene)|ensemblfungi:YOL054W_mRNA(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|sgd:YOL054W(identity)	-	-	crc64:CE0ECBCB6D465554	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:WKqQ0ipAAfKsDRuXJhtTWJcROdc9606	rogid:AvPMRd/GjfaTyQjEfMPhBVcvOs4559292	intact-crc:785A69114DBA9C33|rigid:ntfXmWM1RHuN/MhAxByifxCsJw4	false	sufficient binding region:11-304	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12161	uniprotkb:Q5VSY0	intact:EBI-34372|uniprotkb:D6W213|ensemblfungi:YOL054W	intact:EBI-743722|uniprotkb:Q9BYI2|uniprotkb:Q96LI0|uniprotkb:Q9BYI1|uniprotkb:Q9H225|ensembl:ENSP00000365550	psi-mi:psh1_yeast(display_long)|uniprotkb:PSH1(gene name)|psi-mi:PSH1(display_short)|uniprotkb:POB3/SPT16 histone-associated protein 1(gene name synonym)|uniprotkb:O1263(orf name)|uniprotkb:YOL054W(locus name)	psi-mi:gkap1_human(display_long)|uniprotkb:GKAP42(gene name synonym)|uniprotkb:cGMP-dependent protein kinase-anchoring protein of 42 kDa(gene name synonym)|uniprotkb:FKSG21(orf name)|uniprotkb:GKAP1(gene name)|psi-mi:GKAP1(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11536716|imex:IM-24995-1505	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014587.1|sgd:S000005415|mint:Q12161|dip:DIP-6481N|ensemblfungi:YOL054W(gene)|ensemblfungi:YOL054W_mRNA(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|sgd:YOL054W(identity)	ensembl:ENSG00000165113(gene)|refseq:NP_001129425.1|refseq:NP_079487.2|refseq:XP_011517360.1|refseq:XP_005252298.1|ensembl:ENST00000376371(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0007165"(signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|interpro:IPR026109|dip:DIP-47324N|entrezgene/locuslink:80318(identity)	-	crc64:CE0ECBCB6D465554	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:AvPMRd/GjfaTyQjEfMPhBVcvOs4559292	rogid:WPAqDDTftv300tbwXkusTo6tmUo9606	intact-crc:DD748C93336DF382|rigid:zR49SS5SPC1KEyxWuv82qic6mjc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12161	uniprotkb:P38432	intact:EBI-34372|uniprotkb:D6W213|ensemblfungi:YOL054W	intact:EBI-945751|uniprotkb:B2R931|ensembl:ENSP00000240316	psi-mi:psh1_yeast(display_long)|uniprotkb:PSH1(gene name)|psi-mi:PSH1(display_short)|uniprotkb:POB3/SPT16 histone-associated protein 1(gene name synonym)|uniprotkb:O1263(orf name)|uniprotkb:YOL054W(locus name)	psi-mi:coil_human(display_long)|uniprotkb:COIL(gene name)|psi-mi:COIL(display_short)|uniprotkb:CLN80(gene name synonym)|uniprotkb:p80-coilin(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11536707|imex:IM-24995-1504	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014587.1|sgd:S000005415|mint:Q12161|dip:DIP-6481N|ensemblfungi:YOL054W(gene)|ensemblfungi:YOL054W_mRNA(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|sgd:YOL054W(identity)	refseq:NP_004636.1|dip:DIP-38503N|ensembl:ENSG00000121058(gene)|ensembl:ENST00000240316(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0015030"(Cajal body)|go:"GO:0016020"(membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0030619"(U1 snRNA binding)|go:"GO:0030620"(U2 snRNA binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR024822|interpro:IPR031722|mint:P38432|entrezgene/locuslink:8161(identity)	-	crc64:CE0ECBCB6D465554	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:AvPMRd/GjfaTyQjEfMPhBVcvOs4559292	rogid:hd5p6AbyA/GYNEeca99Mdb41qM09606	intact-crc:43A00657A555DA1C|rigid:i3wOX+p5AKSKep1XoOjc9ScJKf8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12161	uniprotkb:Q9NVV9	intact:EBI-34372|uniprotkb:D6W213|ensemblfungi:YOL054W	intact:EBI-741515|uniprotkb:Q53FQ1|uniprotkb:Q6IA99|ensembl:ENSP00000254250|uniprotkb:A6NCB6|uniprotkb:D3DSY5|uniprotkb:H9KV49	psi-mi:psh1_yeast(display_long)|uniprotkb:PSH1(gene name)|psi-mi:PSH1(display_short)|uniprotkb:POB3/SPT16 histone-associated protein 1(gene name synonym)|uniprotkb:O1263(orf name)|uniprotkb:YOL054W(locus name)	psi-mi:thap1_human(display_long)|uniprotkb:THAP1(gene name)|psi-mi:THAP1(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11536819|imex:IM-24995-1516	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014587.1|sgd:S000005415|mint:Q12161|dip:DIP-6481N|ensemblfungi:YOL054W(gene)|ensemblfungi:YOL054W_mRNA(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|sgd:YOL054W(identity)	refseq:NP_060575.1|ensembl:ENSG00000131931(gene)|ensembl:ENST00000254250(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001650"(fibrillar center)|go:"GO:0001935"(endothelial cell proliferation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007049"(cell cycle)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016605"(PML body)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR006612(Zinc finger, C2CH-type)|interpro:IPR026516|interpro:IPR038441|mint:Q9NVV9|rcsb pdb:2JTG|rcsb pdb:2KO0|rcsb pdb:2L1G|refseq:NP_945354.1|entrezgene/locuslink:55145(identity)	-	crc64:CE0ECBCB6D465554	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:AvPMRd/GjfaTyQjEfMPhBVcvOs4559292	rogid:/KO90pu5tBnIVq9SMx1JYPXFCEQ9606	intact-crc:E97612F7CCCBF916|rigid:cAs9Rb52eg8KN0sVdXYKvRhbD7E	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12161	uniprotkb:Q9NTW7	intact:EBI-34372|uniprotkb:D6W213|ensemblfungi:YOL054W	intact:EBI-711679|uniprotkb:Q9NTS7|uniprotkb:Q9NVH4|ensembl:ENSP00000355179|intact:EBI-10965088|intact:EBI-8637652|intact:MINT-8162399|intact:EBI-745730|uniprotkb:A2A2N4|uniprotkb:Q53H69|uniprotkb:Q53XQ1|uniprotkb:Q5JWM0|uniprotkb:Q5JWM1|uniprotkb:Q8WU98|uniprotkb:Q9H9P1|uniprotkb:Q9NPA5	psi-mi:psh1_yeast(display_long)|uniprotkb:PSH1(gene name)|psi-mi:PSH1(display_short)|uniprotkb:POB3/SPT16 histone-associated protein 1(gene name synonym)|uniprotkb:O1263(orf name)|uniprotkb:YOL054W(locus name)	psi-mi:zf64b_human(display_long)|uniprotkb:Zinc finger protein 338(gene name synonym)|uniprotkb:ZFP64(gene name)|psi-mi:ZFP64(display_short)|uniprotkb:ZNF338(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11536810|imex:IM-24995-1515	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014587.1|sgd:S000005415|mint:Q12161|dip:DIP-6481N|ensemblfungi:YOL054W(gene)|ensemblfungi:YOL054W_mRNA(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|sgd:YOL054W(identity)	refseq:NP_955459.2|ensembl:ENSG00000020256(gene)|ensembl:ENST00000361387(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|rcsb pdb:1X5W|rcsb pdb:2DMD|interpro:IPR036236|refseq:NP_001306075.1|refseq:NP_060667.2|refseq:NP_071371.3|refseq:NP_955458.1|entrezgene/locuslink:55734(identity)	-	crc64:CE0ECBCB6D465554	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2019/04/15	rogid:AvPMRd/GjfaTyQjEfMPhBVcvOs4559292	rogid:aTPOj1Ms8ghVMxTJUwnDUyonUQU9606	intact-crc:04388805EF32760D|rigid:H1grh63KX7jGkuDU2e4yb81EM2Q	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12161	uniprotkb:Q9NTW7	intact:EBI-34372|uniprotkb:D6W213|ensemblfungi:YOL054W	intact:EBI-711679|uniprotkb:Q9NTS7|uniprotkb:Q9NVH4|ensembl:ENSP00000355179|intact:EBI-10965088|intact:EBI-8637652|intact:MINT-8162399|intact:EBI-745730|uniprotkb:A2A2N4|uniprotkb:Q53H69|uniprotkb:Q53XQ1|uniprotkb:Q5JWM0|uniprotkb:Q5JWM1|uniprotkb:Q8WU98|uniprotkb:Q9H9P1|uniprotkb:Q9NPA5	psi-mi:psh1_yeast(display_long)|uniprotkb:PSH1(gene name)|psi-mi:PSH1(display_short)|uniprotkb:POB3/SPT16 histone-associated protein 1(gene name synonym)|uniprotkb:O1263(orf name)|uniprotkb:YOL054W(locus name)	psi-mi:zf64b_human(display_long)|uniprotkb:Zinc finger protein 338(gene name synonym)|uniprotkb:ZFP64(gene name)|psi-mi:ZFP64(display_short)|uniprotkb:ZNF338(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11536801|imex:IM-24995-1514	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014587.1|sgd:S000005415|mint:Q12161|dip:DIP-6481N|ensemblfungi:YOL054W(gene)|ensemblfungi:YOL054W_mRNA(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|sgd:YOL054W(identity)	refseq:NP_955459.2|ensembl:ENSG00000020256(gene)|ensembl:ENST00000361387(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|rcsb pdb:1X5W|rcsb pdb:2DMD|interpro:IPR036236|refseq:NP_001306075.1|refseq:NP_060667.2|refseq:NP_071371.3|refseq:NP_955458.1|entrezgene/locuslink:55734(identity)	-	crc64:CE0ECBCB6D465554	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2019/04/15	rogid:AvPMRd/GjfaTyQjEfMPhBVcvOs4559292	rogid:aTPOj1Ms8ghVMxTJUwnDUyonUQU9606	intact-crc:CCD8F6B63CFE9164|rigid:H1grh63KX7jGkuDU2e4yb81EM2Q	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9HCK0	uniprotkb:Q12161	intact:EBI-3918996|ensembl:ENSP00000362758|ensembl:ENSP00000362760|uniprotkb:B3KQ53|uniprotkb:Q8WTR1	intact:EBI-34372|uniprotkb:D6W213|ensemblfungi:YOL054W	psi-mi:zbt26_human(display_long)|uniprotkb:ZBTB26(gene name)|psi-mi:ZBTB26(display_short)|uniprotkb:KIAA1572(gene name synonym)|uniprotkb:ZNF481(gene name synonym)|uniprotkb:Zinc finger protein 481(gene name synonym)|uniprotkb:Zinc finger protein Bioref(gene name synonym)	psi-mi:psh1_yeast(display_long)|uniprotkb:PSH1(gene name)|psi-mi:PSH1(display_short)|uniprotkb:POB3/SPT16 histone-associated protein 1(gene name synonym)|uniprotkb:O1263(orf name)|uniprotkb:YOL054W(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11536792|imex:IM-24995-1513	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000171448(gene)|ensembl:ENST00000373654(transcript)|ensembl:ENST00000373656(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|refseq:NP_001291292.1|refseq:NP_001291293.1|refseq:NP_065975.1|entrezgene/locuslink:57684(identity)	refseq:NP_014587.1|sgd:S000005415|mint:Q12161|dip:DIP-6481N|ensemblfungi:YOL054W(gene)|ensemblfungi:YOL054W_mRNA(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|sgd:YOL054W(identity)	-	-	crc64:CE0ECBCB6D465554	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:o5XKyl1Z7AtQOJH5HBqkYh5w1n89606	rogid:AvPMRd/GjfaTyQjEfMPhBVcvOs4559292	intact-crc:10584D3B15A31F13|rigid:jKLBoB6/t8N4vc0+0DqdOEqdbWY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12161	uniprotkb:Q9H9D4	intact:EBI-34372|uniprotkb:D6W213|ensemblfungi:YOL054W	intact:EBI-347633|ensembl:ENSP00000309606	psi-mi:psh1_yeast(display_long)|uniprotkb:PSH1(gene name)|psi-mi:PSH1(display_short)|uniprotkb:POB3/SPT16 histone-associated protein 1(gene name synonym)|uniprotkb:O1263(orf name)|uniprotkb:YOL054W(locus name)	psi-mi:zn408_human(display_long)|uniprotkb:ZNF408(gene name)|psi-mi:ZNF408(display_short)|uniprotkb:PFM14(gene name synonym)|uniprotkb:PRDM17(gene name synonym)|uniprotkb:PR domain zinc finger protein 17(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11536783|imex:IM-24995-1512	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014587.1|sgd:S000005415|mint:Q12161|dip:DIP-6481N|ensemblfungi:YOL054W(gene)|ensemblfungi:YOL054W_mRNA(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|sgd:YOL054W(identity)	refseq:NP_001171680.1|refseq:NP_079017.1|ensembl:ENSG00000175213(gene)|ensembl:ENST00000311764(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR044412|entrezgene/locuslink:79797(identity)	-	crc64:CE0ECBCB6D465554	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:AvPMRd/GjfaTyQjEfMPhBVcvOs4559292	rogid:VYheZbRzNxXoFvtRSwYv//yTtOU9606	intact-crc:885801D42ECA53C2|rigid:TLsLvV1Wg8fZQazeThoTw+yKyxE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9BWC9	uniprotkb:Q12161	intact:EBI-711501|ensembl:ENSP00000309681|ensembl:ENSP00000465757|uniprotkb:Q99786|ensembl:ENSP00000466870|ensembl:ENSP00000468539|uniprotkb:B3KUF9|uniprotkb:D3K183	intact:EBI-34372|uniprotkb:D6W213|ensemblfungi:YOL054W	psi-mi:cc106_human(display_long)|uniprotkb:CCDC106(gene name)|psi-mi:CCDC106(display_short)	psi-mi:psh1_yeast(display_long)|uniprotkb:PSH1(gene name)|psi-mi:PSH1(display_short)|uniprotkb:POB3/SPT16 histone-associated protein 1(gene name synonym)|uniprotkb:O1263(orf name)|uniprotkb:YOL054W(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11536774|imex:IM-24995-1511	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000173581(gene)|ensembl:ENST00000308964(transcript)|ensembl:ENST00000586790(transcript)|ensembl:ENST00000588740(transcript)|ensembl:ENST00000591578(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR031591|refseq:NP_037433.2|refseq:XP_005258884.1|refseq:XP_005258885.1|entrezgene/locuslink:29903(identity)	refseq:NP_014587.1|sgd:S000005415|mint:Q12161|dip:DIP-6481N|ensemblfungi:YOL054W(gene)|ensemblfungi:YOL054W_mRNA(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|sgd:YOL054W(identity)	-	-	crc64:CE0ECBCB6D465554	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:i15R76tObPsPuullqYoTxebAIC09606	rogid:AvPMRd/GjfaTyQjEfMPhBVcvOs4559292	intact-crc:670D73F23E5E2B17|rigid:Q6sxByKFDf9HnDLF5/Oba8hmifw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9P1Z2	uniprotkb:Q12208	intact:EBI-749920|uniprotkb:B3KVA8|uniprotkb:Q6FI59|uniprotkb:Q71RC3|uniprotkb:Q86WF8|uniprotkb:Q96JU3|uniprotkb:Q9H090|intact:EBI-2558801|ensembl:ENSP00000449960	intact:EBI-31589|uniprotkb:D6VYC7|ensemblfungi:YLR132C	psi-mi:caco1_human(display_long)|uniprotkb:CALCOCO1(gene name)|psi-mi:CALCOCO1(display_short)|uniprotkb:KIAA1536(gene name synonym)|uniprotkb:Calphoglin(gene name synonym)|uniprotkb:Sarcoma antigen NY-SAR-3(gene name synonym)|uniprotkb:Coiled-coil coactivator protein(gene name synonym)|uniprotkb:PP13275(orf name)|uniprotkb:UNQ2436/PRO4996(orf name)	psi-mi:usb1_yeast(display_long)|uniprotkb:USB1(gene name)|psi-mi:USB1(display_short)|uniprotkb:U six biogenesis protein 1(gene name synonym)|uniprotkb:L3127(orf name)|uniprotkb:YLR132C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11536891|imex:IM-24995-1524	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001137154.1|refseq:NP_065949.1|refseq:XP_016875196.1|dip:DIP-47322N|ensembl:ENSG00000012822(gene)|ensembl:ENST00000550804(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0007165"(signal transduction)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0070016"(armadillo repeat domain binding)|interpro:IPR012852(Coiled-coil transcriptional coactivator-like)|interpro:IPR041611|interpro:IPR041641|mint:Q9P1Z2|entrezgene/locuslink:57658(identity)	refseq:NP_013233.1|sgd:S000004122|dip:DIP-2147N|mint:Q12208|ensemblfungi:YLR132C(gene)|ensemblfungi:YLR132C_mRNA(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0008663"(2',3'-cyclic-nucleotide 2'-phosphodiesterase activity)|go:"GO:0034477"(U6 snRNA 3'-end processing)|go:"GO:1990838"("poly(U)-specific exoribonuclease activity, producing 3' uridine cyclic phosphate ends")|interpro:IPR027521|rcsb pdb:5UQJ|sgd:YLR132C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:4M9Qyq+7GZ1w2UAN6k0ntGQNTvw9606	rogid:vJ6GZFlbc3RC9UKZdc4+yyCFQfs559292	intact-crc:EFC087FFEF3D4991|rigid:uDRyJNp12uggzE8+eBl83Rl0XIc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O95198	uniprotkb:Q12208	intact:EBI-746999|uniprotkb:B2RD18|uniprotkb:Q8N484|uniprotkb:Q8TBH5|uniprotkb:A6NCM7|uniprotkb:B4DFH7|uniprotkb:F5H6M3|ensembl:ENSP00000226725	intact:EBI-31589|uniprotkb:D6VYC7|ensemblfungi:YLR132C	psi-mi:klhl2_human(display_long)|uniprotkb:Actin-binding protein Mayven(gene name synonym)|uniprotkb:KLHL2(gene name)|psi-mi:KLHL2(display_short)	psi-mi:usb1_yeast(display_long)|uniprotkb:USB1(gene name)|psi-mi:USB1(display_short)|uniprotkb:U six biogenesis protein 1(gene name synonym)|uniprotkb:L3127(orf name)|uniprotkb:YLR132C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11536882|imex:IM-24995-1523	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001154993.1|refseq:NP_001154994.1|refseq:NP_009177.3|refseq:NP_001317952.1|refseq:NP_001317953.1|refseq:XP_016863165.1|ensembl:ENSG00000109466(gene)|ensembl:ENST00000226725(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030027"(lamellipodium)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR017096(Kelch-like protein, gigaxonin)|interpro:IPR044072|mint:O95198|rcsb pdb:2XN4|rcsb pdb:4CHB|reactome:R-HSA-8951664|reactome:R-HSA-983168|go:"GO:0042802"(identical protein binding)|entrezgene/locuslink:11275(identity)	refseq:NP_013233.1|sgd:S000004122|dip:DIP-2147N|mint:Q12208|ensemblfungi:YLR132C(gene)|ensemblfungi:YLR132C_mRNA(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0008663"(2',3'-cyclic-nucleotide 2'-phosphodiesterase activity)|go:"GO:0034477"(U6 snRNA 3'-end processing)|go:"GO:1990838"("poly(U)-specific exoribonuclease activity, producing 3' uridine cyclic phosphate ends")|interpro:IPR027521|rcsb pdb:5UQJ|sgd:YLR132C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:tFegR2lJZccRqs4qUjdT3PNjNnk9606	rogid:vJ6GZFlbc3RC9UKZdc4+yyCFQfs559292	intact-crc:6AA208352688050E|rigid:ts2j2gMDPH3Sq0bObY1YW9/ucnc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96BA8	uniprotkb:Q12207	intact:EBI-6942903|ensembl:ENSP00000481956|intact:MINT-268046|intact:MINT-8162577|uniprotkb:Q8N2D5|uniprotkb:Q96CP0	intact:EBI-11922|ensemblfungi:YPR149W|uniprotkb:D6W4E6	psi-mi:cr3l1_human(display_long)|uniprotkb:CREB3L1(gene name)|psi-mi:CREB3L1(display_short)|uniprotkb:OASIS(gene name synonym)|uniprotkb:PSEC0238(orf name)|uniprotkb:Old astrocyte specifically-induced substance(gene name synonym)	psi-mi:nce2_yeast(display_long)|uniprotkb:NCE102(gene name)|psi-mi:NCE102(display_short)|uniprotkb:NCE2(gene name synonym)|uniprotkb:RTG2S2(gene name synonym)|uniprotkb:YPR149W(locus name)|uniprotkb:P9659.2(orf name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11536873|imex:IM-24995-1522	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157613(gene)|ensembl:ENST00000621158(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0070278"(extracellular matrix constituent secretion)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029805|mint:Q96BA8|reactome:R-HSA-8874211|refseq:NP_443086.1|entrezgene/locuslink:90993(identity)	ensemblfungi:YPR149W(gene)|ensemblfungi:YPR149W_mRNA(transcript)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0009306"(protein secretion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032126"(eisosome)|go:"GO:0033101"(cellular bud membrane)|go:"GO:0060237"(regulation of fungal-type cell wall organization)|go:"GO:0061091"(regulation of phospholipid translocation)|go:"GO:0070941"(eisosome assembly)|go:"GO:0071944"(cell periphery)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR008253(Marvel)|go:"GO:0070250"(mating projection membrane)|refseq:NP_015475.1|sgd:S000006353|dip:DIP-5397N|sgd:YPR149W(identity)	-	comment:mint|function:"Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE"	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:sMWUFmBeBBCO+T0Y2CuB/un1lBg9606	rogid:oSD/cLHQuPxlB/s1v7MZUihJ3XM559292	intact-crc:6CF57B6C1275A451|rigid:HJ1uGOLC78ud7cdARENohYzFxfM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12206	uniprotkb:P63279	intact:EBI-20571|uniprotkb:D6W2T3|ensemblfungi:YOR229W	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	psi-mi:wtm2_yeast(display_long)|uniprotkb:WTM2(gene name)|psi-mi:WTM2(display_short)|uniprotkb:YOR50-19(orf name)|uniprotkb:YOR229W(locus name)	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11536864|imex:IM-24995-1521	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014872.1|sgd:S000005755|ensemblfungi:YOR229W(gene)|ensemblfungi:YOR229W_mRNA(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010674"(negative regulation of transcription from RNA polymerase II promoter involved in meiotic cell cycle)|go:"GO:0031939"(obsolete negative regulation of chromatin silencing at telomere)|go:"GO:0034629"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061186"(negative regulation of silent mating-type cassette heterochromatin assembly)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|reactome:R-SCE-3214815|reactome:R-SCE-3214847|reactome:R-SCE-3214858|dip:DIP-1534N|mint:Q12206|sgd:YOR229W(identity)	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N|entrezgene/locuslink:7329(identity)	-	crc64:4A8F5F879B88AA94	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:DCudPHib/PxB5+S+RRONJQyC+QI559292	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	intact-crc:B7FB1BE4D038527B|rigid:H3X0HgaZER9jaXMMANTE6+zp2Xg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9H190	uniprotkb:Q12196	intact:EBI-742426|ensembl:ENSP00000371233|uniprotkb:O95892|uniprotkb:Q5W0X1|uniprotkb:Q9BZ42|uniprotkb:Q9H567|uniprotkb:Q9NRY8|intact:EBI-28983470|ensembl:ENSP00000342935|ensembl:ENSP00000354013	intact:EBI-15224|uniprotkb:Q00602|uniprotkb:D6W2H8|ensemblfungi:YOR119C	psi-mi:sdcb2_human(display_long)|uniprotkb:Similar to TACIP18(gene name synonym)|uniprotkb:SDCBP2(gene name)|psi-mi:SDCBP2(display_short)|uniprotkb:SITAC18(gene name synonym)|uniprotkb:Syndecan-binding protein 2(gene name synonym)	psi-mi:rio1_yeast(display_long)|uniprotkb:RIO1(gene name)|psi-mi:RIO1(display_short)|uniprotkb:RRP10(gene name synonym)|uniprotkb:O3266(orf name)|uniprotkb:YOR3266C(orf name)|uniprotkb:YOR119C(locus name)|uniprotkb:Ribosomal RNA-processing protein 10(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11536855|imex:IM-24995-1520	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001186713.1|refseq:NP_056500.2|refseq:NP_536737.3|ensembl:ENSP00000342935|ensembl:ENSP00000354013|ensembl:ENST00000381808|ensembl:ENSP00000371229|ensembl:ENSP00000371233|ensembl:ENSG00000125775(gene)|ensembl:ENST00000360779(transcript)|ensembl:ENST00000381812(transcript)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007399"(nervous system development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016607"(nuclear speck)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046907"(intracellular transport)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036034|interpro:IPR041489|ensembl:ENST00000339987(transcript)|entrezgene/locuslink:27111(identity)	sgd:S000005645|reactome:R-SCE-6791226|refseq:NP_014762.3|ensemblfungi:YOR119C(gene)|ensemblfungi:YOR119C_mRNA(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0016479"(negative regulation of transcription by RNA polymerase I)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0030874"(nucleolar chromatin)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000234"(positive regulation of rRNA processing)|interpro:IPR000687(RIO kinase)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017407(Serine/threonine-protein kinase Rio1)|interpro:IPR018935|go:"GO:0030490"(maturation of SSU-rRNA)|dip:DIP-4146N|sgd:YOR119C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:vlEtVZkwLTte5PJ4i8ce+SwE/4Y9606	rogid:wLf+Zbnca7AHLdHkLrakVxXltKw559292	intact-crc:0FF00317C78B106F|rigid:BbGHj1eDv/Y2183yBJaJc8WoQFY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12181	uniprotkb:P48775	intact:EBI-37624|uniprotkb:D6W456|ensemblfungi:YPR048W	intact:EBI-743494|ensembl:ENSP00000444788|ensembl:ENSP00000460086|uniprotkb:A8K053	psi-mi:ndor1_yeast(display_long)|uniprotkb:TAH18(gene name)|psi-mi:TAH18(display_short)|uniprotkb:NADPH-dependent FMN and FAD-containing oxidoreductase(gene name synonym)|uniprotkb:YP9499.06(orf name)|uniprotkb:YPR048W(locus name)	psi-mi:t23o_human(display_long)|uniprotkb:Tryptophan pyrrolase(gene name synonym)|uniprotkb:Tryptophan oxygenase(gene name synonym)|uniprotkb:Tryptamin 2,3-dioxygenase(gene name synonym)|uniprotkb:TDO2(gene name)|psi-mi:TDO2(display_short)|uniprotkb:TDO(gene name synonym)|uniprotkb:Tryptophanase(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11536846|imex:IM-24995-1519	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015373.1|sgd:S000006252|dip:DIP-1688N|mint:Q12181|ensemblfungi:YPR048W(gene)|ensemblfungi:YPR048W_mRNA(transcript)|go:"GO:0003958"(NADPH-hemoprotein reductase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006809"(nitric oxide biosynthetic process)|go:"GO:0010181"(FMN binding)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0016651"("oxidoreductase activity, acting on NAD(P)H")|go:"GO:0016709"("oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen")|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0050660"(flavin adenine dinucleotide binding)|go:"GO:0050661"(NADP binding)|go:"GO:1901300"(positive regulation of hydrogen peroxide-mediated programmed cell death)|interpro:IPR001094(Flavodoxin-like)|interpro:IPR001433("Oxidoreductase FAD/NAD(P)-binding")|interpro:IPR001709(Flavoprotein pyridine nucleotide cytochrome reductase)|interpro:IPR003097(FAD-binding, type 1)|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|interpro:IPR017927|interpro:IPR017938|interpro:IPR023173|interpro:IPR028879|interpro:IPR029039|interpro:IPR039261|sgd:YPR048W(identity)	ensembl:ENSG00000151790(gene)|ensembl:ENSG00000262635(gene)|ensembl:ENST00000536354(transcript)|ensembl:ENST00000573403(transcript)|go:"GO:0004833"(tryptophan 2,3-dioxygenase activity)|go:"GO:0005829"(cytosol)|go:"GO:0016597"(amino acid binding)|go:"GO:0019441"(tryptophan catabolic process to kynurenine)|go:"GO:0019442"(tryptophan catabolic process to acetyl-CoA)|go:"GO:0019825"(oxygen binding)|go:"GO:0020037"(heme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051289"(protein homotetramerization)|go:"GO:1904842"(response to nitroglycerin)|interpro:IPR004981(Tryptophan 2,3-dioxygenase)|interpro:IPR037217|mint:P48775|rcsb pdb:4PW8|rcsb pdb:5TI9|rcsb pdb:5TIA|rcsb pdb:6A4I|rcsb pdb:6PYY|rcsb pdb:6PYZ|rcsb pdb:6UD5|rcsb pdb:6VBN|reactome:R-HSA-71240|refseq:NP_005642.1|entrezgene/locuslink:6999(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:rMyciB2K1QEFDXSgbMznNQ811ko559292	rogid:S+cyc710I52nIFQWgKhXFul9QZw9606	intact-crc:2D3C0BC265E9559F|rigid:1u/mvEqDXQHhIKCOK6b8SxQgzxs	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O14641	uniprotkb:Q12181	intact:EBI-740850|ensembl:ENSP00000005340|uniprotkb:Q53XM0|uniprotkb:D3DTN3	intact:EBI-37624|uniprotkb:D6W456|ensemblfungi:YPR048W	psi-mi:dvl2_human(display_long)|uniprotkb:DSH homolog 2(gene name synonym)|uniprotkb:DVL2(gene name)|psi-mi:DVL2(display_short)	psi-mi:ndor1_yeast(display_long)|uniprotkb:TAH18(gene name)|psi-mi:TAH18(display_short)|uniprotkb:NADPH-dependent FMN and FAD-containing oxidoreductase(gene name synonym)|uniprotkb:YP9499.06(orf name)|uniprotkb:YPR048W(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11536837|imex:IM-24995-1518	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004413.1|ensembl:ENSG00000004975(gene)|ensembl:ENST00000005340(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005109"(frizzled binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0007507"(heart development)|go:"GO:0016235"(aggresome)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044340"(canonical Wnt signaling pathway involved in regulation of cell proliferation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0150012"(positive regulation of neuron projection arborization)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008341(Dishevelled-2 region)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:O14641|rcsb pdb:2REY|rcsb pdb:3CBX|rcsb pdb:3CBY|rcsb pdb:3CBZ|rcsb pdb:3CC0|rcsb pdb:4WIP|rcsb pdb:5LNP|rcsb pdb:5SUY|rcsb pdb:5SUZ|rcsb pdb:6IW3|rcsb pdb:6JCK|reactome:R-HSA-201681|reactome:R-HSA-201688|reactome:R-HSA-2028269|reactome:R-HSA-4086400|reactome:R-HSA-4608870|reactome:R-HSA-4641258|reactome:R-HSA-4641262|reactome:R-HSA-5099900|reactome:R-HSA-5368598|reactome:R-HSA-5663220|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9673324|ensembl:ENSP00000005340|dip:DIP-34433N|entrezgene/locuslink:1856(identity)	refseq:NP_015373.1|sgd:S000006252|dip:DIP-1688N|mint:Q12181|ensemblfungi:YPR048W(gene)|ensemblfungi:YPR048W_mRNA(transcript)|go:"GO:0003958"(NADPH-hemoprotein reductase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006809"(nitric oxide biosynthetic process)|go:"GO:0010181"(FMN binding)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0016651"("oxidoreductase activity, acting on NAD(P)H")|go:"GO:0016709"("oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen")|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0050660"(flavin adenine dinucleotide binding)|go:"GO:0050661"(NADP binding)|go:"GO:1901300"(positive regulation of hydrogen peroxide-mediated programmed cell death)|interpro:IPR001094(Flavodoxin-like)|interpro:IPR001433("Oxidoreductase FAD/NAD(P)-binding")|interpro:IPR001709(Flavoprotein pyridine nucleotide cytochrome reductase)|interpro:IPR003097(FAD-binding, type 1)|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|interpro:IPR017927|interpro:IPR017938|interpro:IPR023173|interpro:IPR028879|interpro:IPR029039|interpro:IPR039261|sgd:YPR048W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:2Vdc8oRnT4Mz/j+EXQXrL3AszOc9606	rogid:rMyciB2K1QEFDXSgbMznNQ811ko559292	intact-crc:5CBBDCFB6DD9A9BE|rigid:iqBO894eW/Epd9Iqd6bwnrTVipU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12161	uniprotkb:Q9Y294	intact:EBI-34372|uniprotkb:D6W213|ensemblfungi:YOL054W	intact:EBI-749553|uniprotkb:Q6IA08|uniprotkb:Q9P014|ensembl:ENSP00000229595	psi-mi:psh1_yeast(display_long)|uniprotkb:PSH1(gene name)|psi-mi:PSH1(display_short)|uniprotkb:POB3/SPT16 histone-associated protein 1(gene name synonym)|uniprotkb:O1263(orf name)|uniprotkb:YOL054W(locus name)	psi-mi:asf1a_human(display_long)|uniprotkb:Anti-silencing function protein 1 homolog A(gene name synonym)|uniprotkb:CCG1-interacting factor A(gene name synonym)|uniprotkb:ASF1A(gene name)|psi-mi:ASF1A(display_short)|uniprotkb:CGI-98(orf name)|uniprotkb:HSPC146(orf name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11536828|imex:IM-24995-1517	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014587.1|sgd:S000005415|mint:Q12161|dip:DIP-6481N|ensemblfungi:YOL054W(gene)|ensemblfungi:YOL054W_mRNA(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|sgd:YOL054W(identity)	refseq:NP_054753.1|dip:DIP-29241N|ensembl:ENSG00000111875(gene)|ensembl:ENST00000229595(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0042692"(muscle cell differentiation)|interpro:IPR006818(Anti-silencing protein, ASF1-like)|interpro:IPR036747|mint:Q9Y294|rcsb pdb:1TEY|rcsb pdb:2I32|rcsb pdb:2IIJ|rcsb pdb:2IO5|rcsb pdb:3AAD|rcsb pdb:5C3I|rcsb pdb:6F0G|rcsb pdb:6F0H|rcsb pdb:6ZUF|reactome:R-HSA-2559584|rcsb pdb:6F0F|entrezgene/locuslink:25842(identity)	-	crc64:CE0ECBCB6D465554	caution:This sequence has been withdrawn from Uniprot.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:AvPMRd/GjfaTyQjEfMPhBVcvOs4559292	rogid:rIMptRSOYD+wfp0dMEHjhNNsHXQ9606	intact-crc:0268C32255971F3E|rigid:yPa4Yh8Wg9LcdUz1Ez3K/7ckA9M	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q15041	uniprotkb:Q12259	intact:EBI-714543|ensembl:ENSP00000306788|uniprotkb:B7Z6S5|uniprotkb:B7Z791|uniprotkb:F5GXP4	intact:EBI-30776|uniprotkb:D6VYA8|ensemblfungi:YLR108C	psi-mi:ar6p1_human(display_long)|uniprotkb:ARL6IP(gene name synonym)|uniprotkb:ARL6IP1(gene name)|psi-mi:ARL6IP1(display_short)|uniprotkb:KIAA0069(gene name synonym)|uniprotkb:ARMER(gene name synonym)|uniprotkb:Apoptotic regulator in the membrane of the endoplasmic reticulum(gene name synonym)	psi-mi:yl108_yeast(display_long)|uniprotkb:L2913(orf name)|uniprotkb:YLR108C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11536983|imex:IM-24995-1534	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055976.1|ensembl:ENSG00000170540(gene)|ensembl:ENST00000304414(transcript)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006613"(cotranslational protein targeting to membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0071787"(endoplasmic reticulum tubular network formation)|go:"GO:1903371"(regulation of endoplasmic reticulum tubular network organization)|go:"GO:1990809"(endoplasmic reticulum tubular network membrane organization)|interpro:IPR033301|mint:Q15041|go:"GO:0002038"(positive regulation of L-glutamate import across plasma membrane)|refseq:NP_001300787.1|entrezgene/locuslink:23204(identity)	refseq:NP_013209.1|sgd:S000004098|dip:DIP-4075N|ensemblfungi:YLR108C(gene)|ensemblfungi:YLR108C_mRNA(transcript)|go:"GO:0005634"(nucleus)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|sgd:YLR108C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:3fjkoyvUx25po7xsPcXgpjEeLJg9606	rogid:CzknxXhhvgMp3J0/oi197EgZ05U559292	intact-crc:A1C7544E6D93F0D4|rigid:z/je0n1TVgGyjkTlmk7fJJZoF6Q	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q15025	uniprotkb:Q12259	intact:EBI-357849|uniprotkb:A4F1W8|uniprotkb:O76008|uniprotkb:Q96EL9|uniprotkb:Q99833|uniprotkb:Q9H1J3|uniprotkb:B7Z699|uniprotkb:Q6N077|ensembl:ENSP00000317891|ensembl:ENSP00000428187|ensembl:ENSP00000430760|uniprotkb:A4F1W9|uniprotkb:A4F1X2|uniprotkb:A4F1X4|uniprotkb:A4F1X5|uniprotkb:A4F1X6|uniprotkb:A4F1X7|uniprotkb:A4F1X9|uniprotkb:E7EPY1|uniprotkb:E7ET96|uniprotkb:Q05KP3|uniprotkb:Q05KP4	intact:EBI-30776|uniprotkb:D6VYA8|ensemblfungi:YLR108C	psi-mi:tnip1_human(display_long)|uniprotkb:TNIP1(gene name)|psi-mi:TNIP1(display_short)|uniprotkb:KIAA0113(gene name synonym)|uniprotkb:NAF1(gene name synonym)|uniprotkb:Nef-associated factor 1(gene name synonym)|uniprotkb:HIV-1 Nef-interacting protein(gene name synonym)|uniprotkb:Virion-associated nuclear shuttling protein(gene name synonym)|uniprotkb:Nip40-1(gene name synonym)|uniprotkb:A20-binding inhibitor of NF-kappa-B activation 1(gene name synonym)	psi-mi:yl108_yeast(display_long)|uniprotkb:L2913(orf name)|uniprotkb:YLR108C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11536973|imex:IM-24995-1533	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006049.3|refseq:NP_001239319.1|refseq:NP_001239320.1|refseq:NP_001239321.1|refseq:NP_001239322.1|refseq:NP_001245383.1|dip:DIP-27577N|refseq:NP_001239315.1|ensembl:ENSG00000145901(gene)|ensembl:ENST00000315050(transcript)|ensembl:ENST00000521591(transcript)|ensembl:ENST00000522226(transcript)|go:"GO:0002755"(MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0006952"(defense response)|go:"GO:0006954"(inflammatory response)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0009101"(glycoprotein biosynthetic process)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0085032"(modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade)|go:"GO:1903003"(positive regulation of protein deubiquitination)|interpro:IPR033372|mint:Q15025|reactome:R-HSA-5689896|go:"GO:0051019"(mitogen-activated protein kinase binding)|refseq:NP_001239314.1|refseq:NP_001245384.1|refseq:NP_001245385.1|refseq:XP_006714814.1|refseq:XP_006714815.1|entrezgene/locuslink:10318(identity)	refseq:NP_013209.1|sgd:S000004098|dip:DIP-4075N|ensemblfungi:YLR108C(gene)|ensemblfungi:YLR108C_mRNA(transcript)|go:"GO:0005634"(nucleus)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|sgd:YLR108C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:16Vjb5CuGTAbW2M22qbCxgXtV1o9606	rogid:CzknxXhhvgMp3J0/oi197EgZ05U559292	intact-crc:EB560AC4B3493081|rigid:cWMyQh0kOz3uytxWbjilqKqnh8o	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P35520	uniprotkb:Q12259	intact:EBI-740135|uniprotkb:Q99425|uniprotkb:Q9BWC5|uniprotkb:B2R993|uniprotkb:D3DSK4|intact:EBI-14245939|ensembl:ENSP00000344460|ensembl:ENSP00000352643|ensembl:ENSP00000381225|ensembl:ENSP00000381231	intact:EBI-30776|uniprotkb:D6VYA8|ensemblfungi:YLR108C	psi-mi:cbs_human(display_long)|uniprotkb:CBS(gene name)|psi-mi:CBS(display_short)|uniprotkb:Serine sulfhydrase(gene name synonym)|uniprotkb:Beta-thionase(gene name synonym)	psi-mi:yl108_yeast(display_long)|uniprotkb:L2913(orf name)|uniprotkb:YLR108C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11536963|imex:IM-24995-1532	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000062.1|refseq:NP_001171479.1|refseq:NP_001171480.1|ensembl:ENSG00000160200(gene)|ensembl:ENST00000352178(transcript)|ensembl:ENST00000359624(transcript)|ensembl:ENST00000398158(transcript)|go:"GO:0004122"(cystathionine beta-synthase activity)|ensembl:ENST00000398165(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006535"(cysteine biosynthetic process from serine)|go:"GO:0006563"(L-serine metabolic process)|go:"GO:0006565"(L-serine catabolic process)|go:"GO:0019343"(cysteine biosynthetic process via cystathionine)|go:"GO:0019344"(cysteine biosynthetic process)|go:"GO:0019346"(transsulfuration)|go:"GO:0019448"(L-cysteine catabolic process)|go:"GO:0019825"(oxygen binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0020037"(heme binding)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042262"(DNA protection)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043418"(homocysteine catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0050421"("nitrite reductase (NO-forming) activity")|go:"GO:0050667"(homocysteine metabolic process)|go:"GO:0070025"(carbon monoxide binding)|go:"GO:0070026"(nitric oxide binding)|go:"GO:0070814"(hydrogen sulfide biosynthetic process)|go:"GO:0072341"(modified amino acid binding)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR001216(Cysteine synthase/cystathionine beta-synthase P-phosphate-binding site)|interpro:IPR001926(Pyridoxal phosphate-dependent enzyme, beta subunit)|interpro:IPR005857(Cystathionine beta-synthase)|interpro:IPR036052|mint:P35520|rcsb pdb:1JBQ|rcsb pdb:1M54|rcsb pdb:4COO|rcsb pdb:4L0D|rcsb pdb:4L27|rcsb pdb:4L28|rcsb pdb:4L3V|rcsb pdb:4PCU|rcsb pdb:4UUU|rcsb pdb:5MMS|reactome:R-HSA-1614603|reactome:R-HSA-2408508|refseq:XP_011528079.1|refseq:XP_011528083.1|refseq:XP_011528084.1|refseq:XP_011544396.1|refseq:XP_011544397.1|refseq:XP_011544399.1|refseq:XP_011544400.1|refseq:XP_011544401.1|refseq:NP_001307227.1|refseq:NP_001308002.1|refseq:XP_016883700.1|refseq:XP_016883701.1|refseq:XP_016883702.1|refseq:XP_016883703.1|refseq:XP_016883704.1|refseq:XP_016883705.1|refseq:XP_016883706.1|refseq:XP_016883707.1|refseq:XP_016883978.1|refseq:XP_016883979.1|refseq:XP_016883980.1|refseq:XP_016883981.1|entrezgene/locuslink:875(identity)	refseq:NP_013209.1|sgd:S000004098|dip:DIP-4075N|ensemblfungi:YLR108C(gene)|ensemblfungi:YLR108C_mRNA(transcript)|go:"GO:0005634"(nucleus)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|sgd:YLR108C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:f9eo0cPOHppVY7Nqejag3YyK18s9606	rogid:CzknxXhhvgMp3J0/oi197EgZ05U559292	intact-crc:3F8C5A1E95A2C067|rigid:ewRxuzMo9umkg0gOnUIdBicjMrw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12259	uniprotkb:O76083-2	intact:EBI-30776|uniprotkb:D6VYA8|ensemblfungi:YLR108C	intact:EBI-11524542|ensembl:ENSP00000335242	psi-mi:yl108_yeast(display_long)|uniprotkb:L2913(orf name)|uniprotkb:YLR108C(locus name)	psi-mi:o76083-2(display_long)|uniprotkb:PDE9A(gene name)|psi-mi:PDE9A(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11536954|imex:IM-24995-1531	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013209.1|sgd:S000004098|dip:DIP-4075N|ensemblfungi:YLR108C(gene)|ensemblfungi:YLR108C_mRNA(transcript)|go:"GO:0005634"(nucleus)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|sgd:YLR108C(identity)	intact:EBI-742764(isoform-parent)|ensembl:ENSG00000160191(gene)|ensembl:ENST00000335512(transcript)|uniprotkb:O76083-2(isoform-parent)|entrezgene/locuslink:5152(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:CzknxXhhvgMp3J0/oi197EgZ05U559292	rogid:nTzgeYGOwTM/7VJUgxSnlnDiCFo9606	intact-crc:CBF181D72BBAE471|rigid:fim0piZtR6WM9l8dZTek4YNZ1UE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O60684	uniprotkb:Q12259	intact:EBI-359923|uniprotkb:Q5VVU3|uniprotkb:B2RDC7|ensembl:ENSP00000362728|uniprotkb:D3DPP5	intact:EBI-30776|uniprotkb:D6VYA8|ensemblfungi:YLR108C	psi-mi:ima7_human(display_long)|uniprotkb:KPNA6(gene name)|psi-mi:KPNA6(display_short)|uniprotkb:IPOA7(gene name synonym)|uniprotkb:Karyopherin subunit alpha-6(gene name synonym)	psi-mi:yl108_yeast(display_long)|uniprotkb:L2913(orf name)|uniprotkb:YLR108C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11536945|imex:IM-24995-1530	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_036448.1|ensembl:ENSG00000025800(gene)|ensembl:ENST00000373625(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0016020"(membrane)|go:"GO:0019079"(viral genome replication)|go:"GO:0030682"(mitigation of host defenses by symbiont)|go:"GO:0043657"(host cell)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060135"(maternal process involved in female pregnancy)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0075506"(entry of viral genome into host nucleus through nuclear pore complex via importin)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:1903902"(positive regulation of viral life cycle)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|mint:O60684|rcsb pdb:4UAD|dip:DIP-27609N|entrezgene/locuslink:23633(identity)	refseq:NP_013209.1|sgd:S000004098|dip:DIP-4075N|ensemblfungi:YLR108C(gene)|ensemblfungi:YLR108C_mRNA(transcript)|go:"GO:0005634"(nucleus)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|sgd:YLR108C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:3NsSIcE6BHIqYlvfGRolUKD/5uc9606	rogid:CzknxXhhvgMp3J0/oi197EgZ05U559292	intact-crc:7BE95D88AA4B155B|rigid:j/EP5iQ6fQ+ovJ/LwhRXlkbPquY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12259	uniprotkb:O43597	intact:EBI-30776|uniprotkb:D6VYA8|ensemblfungi:YLR108C	intact:EBI-742487|uniprotkb:Q5T6Z7|ensembl:ENSP00000366306|ensembl:ENSP00000366308|uniprotkb:B2R9J9	psi-mi:yl108_yeast(display_long)|uniprotkb:L2913(orf name)|uniprotkb:YLR108C(locus name)	psi-mi:spy2_human(display_long)|uniprotkb:SPRY2(gene name)|psi-mi:SPRY2(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11536936|imex:IM-24995-1529	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013209.1|sgd:S000004098|dip:DIP-4075N|ensemblfungi:YLR108C(gene)|ensemblfungi:YLR108C_mRNA(transcript)|go:"GO:0005634"(nucleus)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|sgd:YLR108C(identity)	refseq:NP_005833.1|rcsb pdb:5HL0|reactome:R-HSA-1295596|reactome:R-HSA-182971|rcsb pdb:5HKZ|ensembl:ENST00000377102(transcript)|ensembl:ENST00000377104(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|ensembl:ENSG00000136158(gene)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030291"(protein serine/threonine kinase inhibitor activity)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031345"(negative regulation of cell projection organization)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0032587"(ruffle membrane)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0045165"(cell fate commitment)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048513"(animal organ development)|go:"GO:0051387"(negative regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060437"(lung growth)|go:"GO:0060449"(bud elongation involved in lung branching)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:1900747"(negative regulation of vascular endothelial growth factor signaling pathway)|go:"GO:1902747"(negative regulation of lens fiber cell differentiation)|go:"GO:1990752"(microtubule end)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR007875(Sprouty)|interpro:IPR030780|mint:O43597|rcsb pdb:3BUM|rcsb pdb:3OB1|rcsb pdb:5HKY|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|refseq:NP_001305465.1|refseq:NP_001305466.1|refseq:NP_001305467.1|entrezgene/locuslink:10253(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:CzknxXhhvgMp3J0/oi197EgZ05U559292	rogid:u1omauzisc6MdZlogMotUmtauSI9606	intact-crc:E303A75AA23E01A8|rigid:XtjQAWbzgnuhpfG/brce/m9nrpo	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12259	uniprotkb:O00629	intact:EBI-30776|uniprotkb:D6VYA8|ensemblfungi:YLR108C	intact:EBI-396343|uniprotkb:O00190|intact:EBI-28976443|ensembl:ENSP00000334373|uniprotkb:A8K4S6|uniprotkb:D3DNM2	psi-mi:yl108_yeast(display_long)|uniprotkb:L2913(orf name)|uniprotkb:YLR108C(locus name)	psi-mi:ima3_human(display_long)|uniprotkb:KPNA4(gene name)|psi-mi:KPNA4(display_short)|uniprotkb:QIP1(gene name synonym)|uniprotkb:Karyopherin subunit alpha-4(gene name synonym)|uniprotkb:Importin alpha Q1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11536927|imex:IM-24995-1528	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013209.1|sgd:S000004098|dip:DIP-4075N|ensemblfungi:YLR108C(gene)|ensemblfungi:YLR108C_mRNA(transcript)|go:"GO:0005634"(nucleus)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|sgd:YLR108C(identity)	refseq:NP_002259.1|ensembl:ENSG00000186432(gene)|ensembl:ENST00000334256(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0061608"(nuclear import signal receptor activity)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|mint:O00629|rcsb pdb:4UAE|rcsb pdb:5TBK|rcsb pdb:5XZX|rcsb pdb:6BVV|rcsb pdb:6BVZ|rcsb pdb:6BW9|rcsb pdb:6BWA|rcsb pdb:6BWB|rcsb pdb:6WX8|rcsb pdb:7JJL|reactome:R-HSA-1169408|reactome:R-HSA-168276|ensembl:ENSP00000334373|dip:DIP-32982N|entrezgene/locuslink:3840(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:CzknxXhhvgMp3J0/oi197EgZ05U559292	rogid:/cng/xZ42E2juzHNOpuQTP+amx89606	intact-crc:12A1BEF7C1143B97|rigid:fHEBdR7ZCTLMeY5BYZl1AgEg6R8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O00505	uniprotkb:Q12259	intact:EBI-358297|intact:EBI-28976892|ensembl:ENSP00000261667|uniprotkb:O00191|uniprotkb:O43195|uniprotkb:Q96AA7|uniprotkb:Q5JVM9|intact:EBI-742146|uniprotkb:Q8IYQ9	intact:EBI-30776|uniprotkb:D6VYA8|ensemblfungi:YLR108C	psi-mi:ima4_human(display_long)|uniprotkb:KPNA3(gene name)|psi-mi:KPNA3(display_short)|uniprotkb:QIP2(gene name synonym)|uniprotkb:Karyopherin subunit alpha-3(gene name synonym)|uniprotkb:SRP1-gamma(gene name synonym)|uniprotkb:Importin alpha Q2(gene name synonym)	psi-mi:yl108_yeast(display_long)|uniprotkb:L2913(orf name)|uniprotkb:YLR108C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11536918|imex:IM-24995-1527	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000102753(gene)|ensembl:ENST00000261667(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0043657"(host cell)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0075732"(viral penetration into host nucleus)|interpro:IPR000225(Armadillo)|refseq:NP_002258.2|ensembl:ENSP00000261667|dip:DIP-27586N|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|mint:O00505|reactome:R-HSA-1169408|reactome:R-HSA-168276|entrezgene/locuslink:3839(identity)	refseq:NP_013209.1|sgd:S000004098|dip:DIP-4075N|ensemblfungi:YLR108C(gene)|ensemblfungi:YLR108C_mRNA(transcript)|go:"GO:0005634"(nucleus)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|sgd:YLR108C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:kx/oTYWMYG7dhwJHvr1POLD6FTU9606	rogid:CzknxXhhvgMp3J0/oi197EgZ05U559292	intact-crc:3ADF10BC524DC808|rigid:oP3wJrtr1SKXCew1E2EWVOCtGX4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8TAP6	uniprotkb:Q12245	intact:EBI-742887|ensembl:ENSP00000262127|uniprotkb:Q658N5|uniprotkb:Q9H9U7|uniprotkb:B0YJB2|uniprotkb:B4DXG5|uniprotkb:B4DZW1	intact:EBI-2343020|uniprotkb:D6W3M5|uniprotkb:Q6Q5F7|ensemblfungi:YPL144W	psi-mi:cep76_human(display_long)|uniprotkb:CEP76(gene name)|psi-mi:CEP76(display_short)|uniprotkb:C18orf9(gene name synonym)	psi-mi:poc4_yeast(display_long)|uniprotkb:POC4(gene name)|psi-mi:POC4(display_short)|uniprotkb:YPL144W(locus name)|uniprotkb:DMP1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11536909|imex:IM-24995-1526	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_079175.2|ensembl:ENSG00000101624(gene)|ensembl:ENST00000262127(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0046599"(regulation of centriole replication)|interpro:IPR028926|interpro:IPR038765|mint:Q8TAP6|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_001258918.1|entrezgene/locuslink:79959(identity)	refseq:NP_015181.1|sgd:S000006065|dip:DIP-8930N|mint:Q12245|ensemblfungi:YPL144W(gene)|ensemblfungi:YPL144W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043248"(proteasome assembly)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|interpro:IPR018854|rcsb pdb:2Z5B|rcsb pdb:2Z5C|sgd:YPL144W(identity)	-	-	crc64:1CC7C6074CF4AC08	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:fWzb8oIU35oVWomyDrf8u5sbxUk9606	rogid:IT8/s4OOCv/pZK9VkZJ5J8ye438559292	intact-crc:FFEF8848CF620831|rigid:a56IIFxvfAseknEUcfwhRs6fS6c	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12211	uniprotkb:P35606	intact:EBI-14272|uniprotkb:D6W3F8|ensemblfungi:YPL212C	intact:EBI-1056534|uniprotkb:B4DZI8|intact:EBI-11019844|ensembl:ENSP00000329419	psi-mi:pus1_yeast(display_long)|uniprotkb:YPL212C(locus name)|uniprotkb:tRNA-uridine isomerase 1(gene name synonym)|uniprotkb:PUS1(gene name)|psi-mi:PUS1(display_short)|uniprotkb:tRNA pseudouridylate synthase 1(gene name synonym)	psi-mi:copb2_human(display_long)|uniprotkb:COPB2(gene name)|psi-mi:COPB2(display_short)|uniprotkb:Beta'-coat protein(gene name synonym)|uniprotkb:p102(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11536900|imex:IM-24995-1525	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015112.1|sgd:S000006133|ensemblfungi:YPL212C(gene)|ensemblfungi:YPL212C_mRNA(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006400"(tRNA modification)|go:"GO:0009982"(pseudouridine synthase activity)|go:"GO:0031120"(snRNA pseudouridine synthesis)|go:"GO:1990481"(mRNA pseudouridine synthesis)|interpro:IPR001406(tRNA pseudouridine synthase)|interpro:IPR020094|go:"GO:0031119"(tRNA pseudouridine synthesis)|interpro:IPR020097|interpro:IPR020103|interpro:IPR041708|mint:Q12211|dip:DIP-5344N|sgd:YPL212C(identity)	refseq:NP_004757.1|ensembl:ENSG00000184432(gene)|ensembl:ENST00000333188(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0030133"(transport vesicle)|go:"GO:1901998"(toxin transport)|interpro:IPR001680(WD40 repeat)|interpro:IPR006692(Coatomer, WD associated region)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016453(Coatomer, beta' subunit)|interpro:IPR020472|interpro:IPR036322|mint:P35606|reactome:R-HSA-6807878|reactome:R-HSA-6811434|refseq:XP_016863001.1|dip:DIP-27603N|entrezgene/locuslink:9276(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:u8LVhy6qxRakYcjrKYN0QGn34iM559292	rogid:zkd7lOeV+OvHglnAJg6cXoMhgbg9606	intact-crc:A6EE04CAC043EF52|rigid:h57e73cZRMo6xEO7IjDBkBDTFCc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12259	uniprotkb:Q9HCK0	intact:EBI-30776|uniprotkb:D6VYA8|ensemblfungi:YLR108C	intact:EBI-3918996|ensembl:ENSP00000362758|ensembl:ENSP00000362760|uniprotkb:B3KQ53|uniprotkb:Q8WTR1	psi-mi:yl108_yeast(display_long)|uniprotkb:L2913(orf name)|uniprotkb:YLR108C(locus name)	psi-mi:zbt26_human(display_long)|uniprotkb:ZBTB26(gene name)|psi-mi:ZBTB26(display_short)|uniprotkb:KIAA1572(gene name synonym)|uniprotkb:ZNF481(gene name synonym)|uniprotkb:Zinc finger protein 481(gene name synonym)|uniprotkb:Zinc finger protein Bioref(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11537085|imex:IM-24995-1544	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013209.1|sgd:S000004098|dip:DIP-4075N|ensemblfungi:YLR108C(gene)|ensemblfungi:YLR108C_mRNA(transcript)|go:"GO:0005634"(nucleus)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|sgd:YLR108C(identity)	ensembl:ENSG00000171448(gene)|ensembl:ENST00000373654(transcript)|ensembl:ENST00000373656(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|refseq:NP_001291292.1|refseq:NP_001291293.1|refseq:NP_065975.1|entrezgene/locuslink:57684(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:CzknxXhhvgMp3J0/oi197EgZ05U559292	rogid:o5XKyl1Z7AtQOJH5HBqkYh5w1n89606	intact-crc:810A429823B050CE|rigid:5tlb+6Z+vOSQbEKkHD1npNvJT58	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9C0F1	uniprotkb:Q12259	intact:EBI-744115|uniprotkb:A8K8W9|uniprotkb:B3KT53|uniprotkb:Q8IXZ4|uniprotkb:A8MW11|uniprotkb:D3DP42|ensembl:ENSP00000296519|ensembl:ENSP00000380009|ensembl:ENSP00000423153	intact:EBI-30776|uniprotkb:D6VYA8|ensemblfungi:YLR108C	psi-mi:cep44_human(display_long)|uniprotkb:HBV PreS1-transactivated protein 3(gene name synonym)|uniprotkb:CEP44(gene name)|psi-mi:CEP44(display_short)|uniprotkb:KIAA1712(gene name synonym)	psi-mi:yl108_yeast(display_long)|uniprotkb:L2913(orf name)|uniprotkb:YLR108C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11537076|imex:IM-24995-1543	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001035247.1|refseq:NP_001138786.1|refseq:XP_011530587.1|refseq:XP_011530588.1|refseq:XP_011530589.1|refseq:XP_016864143.1|refseq:XP_016864144.1|ensembl:ENSG00000164118(gene)|ensembl:ENST00000296519(transcript)|ensembl:ENST00000396791(transcript)|ensembl:ENST00000503780(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007099"(centriole replication)|go:"GO:0008017"(microtubule binding)|go:"GO:0010457"(centriole-centriole cohesion)|go:"GO:0030496"(midbody)|interpro:IPR029157|interpro:IPR033603|mint:Q9C0F1|entrezgene/locuslink:80817(identity)	refseq:NP_013209.1|sgd:S000004098|dip:DIP-4075N|ensemblfungi:YLR108C(gene)|ensemblfungi:YLR108C_mRNA(transcript)|go:"GO:0005634"(nucleus)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|sgd:YLR108C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:gDTC64oDhudGdsssC7v+suIHZkA9606	rogid:CzknxXhhvgMp3J0/oi197EgZ05U559292	intact-crc:CD10421A4A2A96C0|rigid:tQl1GNaqNU+YjUPEuZ8OaQB9VPM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12259	uniprotkb:Q99750	intact:EBI-30776|uniprotkb:D6VYA8|ensemblfungi:YLR108C	intact:EBI-724076|ensembl:ENSP00000230321|ensembl:ENSP00000362142	psi-mi:yl108_yeast(display_long)|uniprotkb:L2913(orf name)|uniprotkb:YLR108C(locus name)	psi-mi:mdfi_human(display_long)|uniprotkb:Myogenic repressor I-mf(gene name synonym)|uniprotkb:MDFI(gene name)|psi-mi:MDFI(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11537062|imex:IM-24995-1542	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013209.1|sgd:S000004098|dip:DIP-4075N|ensemblfungi:YLR108C(gene)|ensemblfungi:YLR108C_mRNA(transcript)|go:"GO:0005634"(nucleus)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|sgd:YLR108C(identity)	refseq:NP_005577.1|ensembl:ENSG00000112559(gene)|ensembl:ENST00000230321(transcript)|ensembl:ENST00000373051(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR026134|mint:Q99750|refseq:NP_001287733.1|refseq:NP_001287734.1|refseq:NP_001287735.1|entrezgene/locuslink:4188(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:CzknxXhhvgMp3J0/oi197EgZ05U559292	rogid:V3vU0fihMOW18DMHAiDbuZ3asNU9606	intact-crc:2843C24FCF4D0AF0|rigid:WRPqLXL2xvGWgfOHpP3Zau+273c	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12259	uniprotkb:Q96IK5	intact:EBI-30776|uniprotkb:D6VYA8|ensemblfungi:YLR108C	intact:EBI-2548508|ensembl:ENSP00000282570|uniprotkb:Q9H826|uniprotkb:Q9H8V7|uniprotkb:Q9H927	psi-mi:yl108_yeast(display_long)|uniprotkb:L2913(orf name)|uniprotkb:YLR108C(locus name)	psi-mi:gmcl1_human(display_long)|uniprotkb:GMCL1(gene name)|psi-mi:GMCL1(display_short)|uniprotkb:GCL(gene name synonym)|uniprotkb:BTBD13(gene name synonym)|uniprotkb:SPATA29(gene name synonym)|uniprotkb:Spermatogenesis-associated protein 29(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11537050|imex:IM-24995-1541	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013209.1|sgd:S000004098|dip:DIP-4075N|ensemblfungi:YLR108C(gene)|ensemblfungi:YLR108C_mRNA(transcript)|go:"GO:0005634"(nucleus)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|sgd:YLR108C(identity)	ensembl:ENSG00000087338(gene)|ensembl:ENST00000282570(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0007281"(germ cell development)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016363"(nuclear matrix)|go:"GO:0042802"(identical protein binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR043380|refseq:NP_848526.1|entrezgene/locuslink:64395(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:CzknxXhhvgMp3J0/oi197EgZ05U559292	rogid:ED8yqySVu7BWxpw3DUSNBZSQWrk9606	intact-crc:AC7BEA260ABD66BE|rigid:gCLE2yb9pKKf3IwPtUB5pCdLuxk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12259	uniprotkb:Q96BR9	intact:EBI-30776|uniprotkb:D6VYA8|ensemblfungi:YLR108C	intact:EBI-742740|uniprotkb:Q8IUL5|uniprotkb:Q8IWR9|uniprotkb:Q8N2Y5|uniprotkb:Q96BX0|ensembl:ENSP00000362609	psi-mi:yl108_yeast(display_long)|uniprotkb:L2913(orf name)|uniprotkb:YLR108C(locus name)	psi-mi:zbt8a_human(display_long)|uniprotkb:ZBTB8A(gene name)|psi-mi:ZBTB8A(display_short)|uniprotkb:BOZF1(gene name synonym)|uniprotkb:BTB/POZ and zinc-finger domain-containing factor(gene name synonym)|uniprotkb:BTB/POZ and zinc-finger domains factor on chromosome 1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11537041|imex:IM-24995-1540	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013209.1|sgd:S000004098|dip:DIP-4075N|ensemblfungi:YLR108C(gene)|ensemblfungi:YLR108C_mRNA(transcript)|go:"GO:0005634"(nucleus)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|sgd:YLR108C(identity)	ensembl:ENSG00000160062(gene)|ensembl:ENST00000373510(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|refseq:NP_001035531.2|refseq:NP_001278425.1|entrezgene/locuslink:653121(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:CzknxXhhvgMp3J0/oi197EgZ05U559292	rogid:tsrPT2tHvuBryODKgRXnceXz9s09606	intact-crc:8FE59FF9B953A65D|rigid:be6cdCb6O91+sI6vlgtKlQHNKKQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12259	uniprotkb:Q92734	intact:EBI-30776|uniprotkb:D6VYA8|ensemblfungi:YLR108C	intact:EBI-357061|uniprotkb:Q15656|intact:EBI-357314|uniprotkb:Q969I2|uniprotkb:D3DN49|uniprotkb:K0J5S8|uniprotkb:K0J6K2|intact:EBI-28969365|ensembl:ENSP00000240851|ensembl:ENSP00000419960|ensembl:ENSP00000420797|ensembl:ENSP00000501815|ensembl:ENSP00000502071|ensembl:ENSP00000502450|ensembl:ENSP00000502592|ensembl:ENSP00000502734|uniprotkb:G5E9V1	psi-mi:yl108_yeast(display_long)|uniprotkb:L2913(orf name)|uniprotkb:YLR108C(locus name)	psi-mi:tfg_human(display_long)|uniprotkb:TFG(gene name)|psi-mi:TFG(display_short)|uniprotkb:TRK-fused gene protein(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11537032|imex:IM-24995-1539	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013209.1|sgd:S000004098|dip:DIP-4075N|ensemblfungi:YLR108C(gene)|ensemblfungi:YLR108C_mRNA(transcript)|go:"GO:0005634"(nucleus)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|sgd:YLR108C(identity)	refseq:NP_001007566.1|refseq:NP_001182407.1|refseq:NP_001182408.1|refseq:NP_006061.2|ensembl:ENSP00000240851|ensembl:ENST00000463568|ensembl:ENSP00000419504|ensembl:ENST00000476228|ensembl:ENSP00000417952|ensembl:ENSP00000420797|ensembl:ENSP00000419960|ensembl:ENST00000615993|ensembl:ENSP00000479269|ensembl:ENST00000620299|ensembl:ENSP00000479981|ensembl:ENSP00000502734|ensembl:ENST00000674645|ensembl:ENSP00000501892|ensembl:ENST00000674758|ensembl:ENSP00000502502|ensembl:ENST00000675047|ensembl:ENSP00000502497|ensembl:ENSP00000502592|ensembl:ENST00000675420|ensembl:ENSP00000502516|ensembl:ENSP00000502450|ensembl:ENST00000675543|ensembl:ENSP00000501815|ensembl:ENST00000675586|ensembl:ENSP00000502329|ensembl:ENST00000676111|ensembl:ENSP00000502139|ensembl:ENST00000676308|ensembl:ENSP00000502697|ensembl:ENSP00000502071|ensembl:ENST00000676431|ensembl:ENSP00000502698|ensembl:ENSP00000502229|refseq:XP_006713535.1|refseq:XP_006713536.1|ensembl:ENSG00000114354(gene)|ensembl:ENST00000240851(transcript)|ensembl:ENST00000487505(transcript)|ensembl:ENST00000490574(transcript)|ensembl:ENST00000674615(transcript)|ensembl:ENST00000675243(transcript)|ensembl:ENST00000675499(transcript)|ensembl:ENST00000675553(transcript)|ensembl:ENST00000676395(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048208"(COPII vesicle coating)|go:"GO:0070971"(endoplasmic reticulum exit site)|interpro:IPR000270(Octicosapeptide/Phox/Bem1p)|interpro:IPR033512|interpro:IPR034857|mint:Q92734|reactome:R-HSA-204005|refseq:XP_011510636.1|refseq:XP_005247123.1|refseq:XP_016861016.1|refseq:XP_016861017.1|refseq:XP_016861018.1|refseq:XP_016861019.1|entrezgene/locuslink:10342(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:CzknxXhhvgMp3J0/oi197EgZ05U559292	rogid:y7aghh0X3Ewgpzcx5h5nB+X2dII9606	intact-crc:FB599C9988A07B22|rigid:Kmbywoug59wyzgm0IQiNuBFMdqc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8WV44	uniprotkb:Q12259	intact:EBI-725997|uniprotkb:Q5BKT0|uniprotkb:Q7L484|uniprotkb:Q96Q10|intact:EBI-1551110|uniprotkb:Q9BSL8|uniprotkb:B3KNJ6|uniprotkb:D3DWR9|ensembl:ENSP00000320869	intact:EBI-30776|uniprotkb:D6VYA8|ensemblfungi:YLR108C	psi-mi:tri41_human(display_long)|uniprotkb:TRIM41(gene name)|psi-mi:TRIM41(display_short)|uniprotkb:RINCK(gene name synonym)|uniprotkb:Tripartite motif-containing protein 41(gene name synonym)|uniprotkb:RING finger-interacting protein with C kinase(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM41(gene name synonym)	psi-mi:yl108_yeast(display_long)|uniprotkb:L2913(orf name)|uniprotkb:YLR108C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11537021|imex:IM-24995-1538	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_291027.3|refseq:NP_963921.1|ensembl:ENSG00000146063(gene)|ensembl:ENST00000315073(transcript)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0042802"(identical protein binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071225"(cellular response to muramyl dipeptide)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR042828|interpro:IPR043136|mint:Q8WV44|rcsb pdb:2EGM|reactome:R-HSA-983168|entrezgene/locuslink:90933(identity)	refseq:NP_013209.1|sgd:S000004098|dip:DIP-4075N|ensemblfungi:YLR108C(gene)|ensemblfungi:YLR108C_mRNA(transcript)|go:"GO:0005634"(nucleus)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|sgd:YLR108C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:BVqf0OHXPGsYe8F66mHzvD4XQ549606	rogid:CzknxXhhvgMp3J0/oi197EgZ05U559292	intact-crc:DB0D6A84B1AD9445|rigid:/RwvnIwtpDT3qyFJmHFHGzE5acQ	false	sufficient binding region:86-630	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8N6L0	uniprotkb:Q12259	intact:EBI-749265|uniprotkb:Q96MC3|ensembl:ENSP00000404220	intact:EBI-30776|uniprotkb:D6VYA8|ensemblfungi:YLR108C	psi-mi:kash5_human(display_long)|uniprotkb:KASH5(gene name)|psi-mi:KASH5(display_short)|uniprotkb:CCDC155(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 155(gene name synonym)|uniprotkb:KASH domain-containing protein 5(gene name synonym)	psi-mi:yl108_yeast(display_long)|uniprotkb:L2913(orf name)|uniprotkb:YLR108C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11537012|imex:IM-24995-1537	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_653289.3|ensembl:ENSG00000161609(gene)|ensembl:ENST00000447857(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034397"(telomere localization)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051225"(spindle assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0090172"(microtubule cytoskeleton organization involved in homologous chromosome segregation)|go:"GO:0090220"(chromosome localization to nuclear envelope involved in homologous chromosome segregation)|go:"GO:0090619"(meiotic spindle pole)|interpro:IPR011992(EF-Hand type)|interpro:IPR028168|interpro:IPR028170|interpro:IPR039508|mint:Q8N6L0|rcsb pdb:6R2I|rcsb pdb:6WMF|entrezgene/locuslink:147872(identity)	refseq:NP_013209.1|sgd:S000004098|dip:DIP-4075N|ensemblfungi:YLR108C(gene)|ensemblfungi:YLR108C_mRNA(transcript)|go:"GO:0005634"(nucleus)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|sgd:YLR108C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Wl9L7AcvDHCZuKjYLn8QgGIbZTc9606	rogid:CzknxXhhvgMp3J0/oi197EgZ05U559292	intact-crc:3C7AE7935F16F003|rigid:CL3/fEzVgFnXthyaCwbA3LhmLeI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8IYA8	uniprotkb:Q12259	intact:EBI-8638439|intact:EBI-28969497|ensembl:ENSP00000296449|ensembl:ENSP00000391788|ensembl:ENSP00000407837|uniprotkb:C9JJL0|uniprotkb:Q96LP7|intact:MINT-8162095|uniprotkb:Q05DG9	intact:EBI-30776|uniprotkb:D6VYA8|ensemblfungi:YLR108C	psi-mi:iho1_human(display_long)|uniprotkb:IHO1(gene name)|psi-mi:IHO1(display_short)|uniprotkb:CCDC36(gene name synonym)|uniprotkb:Cancer/testis antigen 74(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 36(gene name synonym)	psi-mi:yl108_yeast(display_long)|uniprotkb:L2913(orf name)|uniprotkb:YLR108C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11537001|imex:IM-24995-1536	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000296449|ensembl:ENST00000366429|ensembl:ENSP00000403700|ensembl:ENSP00000391788|ensembl:ENSP00000407837|ensembl:ENSG00000173421(gene)|ensembl:ENST00000296449(transcript)|ensembl:ENST00000438782(transcript)|ensembl:ENST00000452691(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0006310"(DNA recombination)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0042138"(meiotic DNA double-strand break formation)|go:"GO:0048477"(oogenesis)|go:"GO:0060629"(regulation of homologous chromosome segregation)|interpro:IPR031529|mint:Q8IYA8|refseq:XP_011531974.1|refseq:XP_011531975.1|refseq:NP_001128669.1|refseq:NP_835467.2|refseq:XP_006713187.1|entrezgene/locuslink:339834(identity)	refseq:NP_013209.1|sgd:S000004098|dip:DIP-4075N|ensemblfungi:YLR108C(gene)|ensemblfungi:YLR108C_mRNA(transcript)|go:"GO:0005634"(nucleus)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|sgd:YLR108C(identity)	-	comment:mint	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:+TNQLExkhmC1NWqsE240Cx7zFVU9606	rogid:CzknxXhhvgMp3J0/oi197EgZ05U559292	intact-crc:55E2F9FC036AC408|rigid:cm1ZX5U6As/tFOEf2aR5MhHMFu0	false	sufficient binding region:11-594	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q6RW13-2	uniprotkb:Q12259	intact:EBI-11522760|ensembl:ENSP00000365816	intact:EBI-30776|uniprotkb:D6VYA8|ensemblfungi:YLR108C	psi-mi:q6rw13-2(display_long)|uniprotkb:AGTRAP(gene name)|psi-mi:AGTRAP(display_short)|uniprotkb:AT1 receptor-associated protein(gene name synonym)|uniprotkb:ATRAP(gene name synonym)	psi-mi:yl108_yeast(display_long)|uniprotkb:L2913(orf name)|uniprotkb:YLR108C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11536992|imex:IM-24995-1535	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000177674(gene)|ensembl:ENST00000376629(transcript)|intact:EBI-741181(isoform-parent)|uniprotkb:Q6RW13-2(isoform-parent)|entrezgene/locuslink:57085(identity)	refseq:NP_013209.1|sgd:S000004098|dip:DIP-4075N|ensemblfungi:YLR108C(gene)|ensemblfungi:YLR108C_mRNA(transcript)|go:"GO:0005634"(nucleus)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|sgd:YLR108C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:PNzVis/8puQZBJ562gCqZKc078s9606	rogid:CzknxXhhvgMp3J0/oi197EgZ05U559292	intact-crc:90EF0BD4411FC41A|rigid:Y/xDLctUWzrTeJsAQfmQs5tk0h8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9HCK0	uniprotkb:Q12306	intact:EBI-3918996|ensembl:ENSP00000362758|ensembl:ENSP00000362760|uniprotkb:B3KQ53|uniprotkb:Q8WTR1	intact:EBI-17490|uniprotkb:D6VTD1|ensemblfungi:YDR510W	psi-mi:zbt26_human(display_long)|uniprotkb:ZBTB26(gene name)|psi-mi:ZBTB26(display_short)|uniprotkb:KIAA1572(gene name synonym)|uniprotkb:ZNF481(gene name synonym)|uniprotkb:Zinc finger protein 481(gene name synonym)|uniprotkb:Zinc finger protein Bioref(gene name synonym)	psi-mi:smt3_yeast(display_long)|uniprotkb:SMT3(gene name)|psi-mi:SMT3(display_short)|uniprotkb:D9719.15(orf name)|uniprotkb:YDR510W(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11537170|imex:IM-24995-1553	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000171448(gene)|ensembl:ENST00000373654(transcript)|ensembl:ENST00000373656(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|refseq:NP_001291292.1|refseq:NP_001291293.1|refseq:NP_065975.1|entrezgene/locuslink:57684(identity)	refseq:NP_010798.1|sgd:S000002918|ensemblfungi:YDR510W(gene)|ensemblfungi:YDR510W_mRNA(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005940"(septin ring)|go:"GO:0016925"(protein sumoylation)|go:"GO:0031386"(protein tag)|go:"GO:0042802"(identical protein binding)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR022617|interpro:IPR029071|rcsb pdb:1EUV|rcsb pdb:1L2N|rcsb pdb:2EKE|rcsb pdb:3PGE|rcsb pdb:3QHT|rcsb pdb:3TIX|rcsb pdb:3UF8|rcsb pdb:3UQA|rcsb pdb:3UQB|rcsb pdb:3V60|rcsb pdb:3V61|rcsb pdb:3V62|rcsb pdb:3VAW|rcsb pdb:4FN2|rcsb pdb:4G50|rcsb pdb:4GGQ|rcsb pdb:4GIV|rcsb pdb:5D6J|rcsb pdb:5JNE|rcsb pdb:5KLX|rcsb pdb:5V8T|rcsb pdb:5YC2|rcsb pdb:5YCA|rcsb pdb:6CFP|rcsb pdb:6P81|rcsb pdb:6Q2S|rcsb pdb:6RPQ|rcsb pdb:6UKM|rcsb pdb:6UKU|rcsb pdb:6UKV|rcsb pdb:6UKW|rcsb pdb:6UKX|rcsb pdb:6UKY|rcsb pdb:6UKZ|rcsb pdb:6UL0|rcsb pdb:6VEL|rcsb pdb:6VW2|rcsb pdb:7LTO|reactome:R-SCE-3065676|reactome:R-SCE-3065678|reactome:R-SCE-3065679|reactome:R-SCE-3108214|reactome:R-SCE-3108232|reactome:R-SCE-3232118|reactome:R-SCE-3899300|reactome:R-SCE-4085377|reactome:R-SCE-4551638|reactome:R-SCE-4570464|reactome:R-SCE-4615885|reactome:R-SCE-9615933|dip:DIP-1364N|mint:Q12306|sgd:YDR510W(identity)	-	-	crc64:A2790DE7F315E1A7	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:o5XKyl1Z7AtQOJH5HBqkYh5w1n89606	rogid:oFdVBxN9WlDXTM7oAnv+1vfcXFQ559292	intact-crc:D4EE073A087DCA36|rigid:i8fjIddAhSTcipIKW5M/FEzX96I	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P63279	uniprotkb:Q12306	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	intact:EBI-17490|uniprotkb:D6VTD1|ensemblfungi:YDR510W	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:smt3_yeast(display_long)|uniprotkb:SMT3(gene name)|psi-mi:SMT3(display_short)|uniprotkb:D9719.15(orf name)|uniprotkb:YDR510W(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11537161|imex:IM-24995-1552	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N|entrezgene/locuslink:7329(identity)	refseq:NP_010798.1|sgd:S000002918|ensemblfungi:YDR510W(gene)|ensemblfungi:YDR510W_mRNA(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005940"(septin ring)|go:"GO:0016925"(protein sumoylation)|go:"GO:0031386"(protein tag)|go:"GO:0042802"(identical protein binding)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR022617|interpro:IPR029071|rcsb pdb:1EUV|rcsb pdb:1L2N|rcsb pdb:2EKE|rcsb pdb:3PGE|rcsb pdb:3QHT|rcsb pdb:3TIX|rcsb pdb:3UF8|rcsb pdb:3UQA|rcsb pdb:3UQB|rcsb pdb:3V60|rcsb pdb:3V61|rcsb pdb:3V62|rcsb pdb:3VAW|rcsb pdb:4FN2|rcsb pdb:4G50|rcsb pdb:4GGQ|rcsb pdb:4GIV|rcsb pdb:5D6J|rcsb pdb:5JNE|rcsb pdb:5KLX|rcsb pdb:5V8T|rcsb pdb:5YC2|rcsb pdb:5YCA|rcsb pdb:6CFP|rcsb pdb:6P81|rcsb pdb:6Q2S|rcsb pdb:6RPQ|rcsb pdb:6UKM|rcsb pdb:6UKU|rcsb pdb:6UKV|rcsb pdb:6UKW|rcsb pdb:6UKX|rcsb pdb:6UKY|rcsb pdb:6UKZ|rcsb pdb:6UL0|rcsb pdb:6VEL|rcsb pdb:6VW2|rcsb pdb:7LTO|reactome:R-SCE-3065676|reactome:R-SCE-3065678|reactome:R-SCE-3065679|reactome:R-SCE-3108214|reactome:R-SCE-3108232|reactome:R-SCE-3232118|reactome:R-SCE-3899300|reactome:R-SCE-4085377|reactome:R-SCE-4551638|reactome:R-SCE-4570464|reactome:R-SCE-4615885|reactome:R-SCE-9615933|dip:DIP-1364N|mint:Q12306|sgd:YDR510W(identity)	-	-	crc64:A2790DE7F315E1A7	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	rogid:oFdVBxN9WlDXTM7oAnv+1vfcXFQ559292	intact-crc:9C5D398416BA621B|rigid:9MPooZox+lbk1ZQnq+lAYhd58B0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P23497-2	uniprotkb:Q12306	intact:EBI-6589365|ensembl:ENSP00000386404	intact:EBI-17490|uniprotkb:D6VTD1|ensemblfungi:YDR510W	psi-mi:p23497-2(display_long)|uniprotkb:SP100(isoform synonym)|uniprotkb:SP100(gene name)|psi-mi:SP100(display_short)|uniprotkb:Nuclear dot-associated Sp100 protein(gene name synonym)|uniprotkb:Speckled 100 kDa(gene name synonym)|uniprotkb:SP100A(isoform synonym)	psi-mi:smt3_yeast(display_long)|uniprotkb:SMT3(gene name)|psi-mi:SMT3(display_short)|uniprotkb:D9719.15(orf name)|uniprotkb:YDR510W(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11537152|imex:IM-24995-1551	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-751145(isoform-parent)|uniprotkb:P23497-2(isoform-parent)|ensembl:ENSG00000067066(gene)|ensembl:ENST00000409341(transcript)|entrezgene/locuslink:6672(identity)	refseq:NP_010798.1|sgd:S000002918|ensemblfungi:YDR510W(gene)|ensemblfungi:YDR510W_mRNA(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005940"(septin ring)|go:"GO:0016925"(protein sumoylation)|go:"GO:0031386"(protein tag)|go:"GO:0042802"(identical protein binding)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR022617|interpro:IPR029071|rcsb pdb:1EUV|rcsb pdb:1L2N|rcsb pdb:2EKE|rcsb pdb:3PGE|rcsb pdb:3QHT|rcsb pdb:3TIX|rcsb pdb:3UF8|rcsb pdb:3UQA|rcsb pdb:3UQB|rcsb pdb:3V60|rcsb pdb:3V61|rcsb pdb:3V62|rcsb pdb:3VAW|rcsb pdb:4FN2|rcsb pdb:4G50|rcsb pdb:4GGQ|rcsb pdb:4GIV|rcsb pdb:5D6J|rcsb pdb:5JNE|rcsb pdb:5KLX|rcsb pdb:5V8T|rcsb pdb:5YC2|rcsb pdb:5YCA|rcsb pdb:6CFP|rcsb pdb:6P81|rcsb pdb:6Q2S|rcsb pdb:6RPQ|rcsb pdb:6UKM|rcsb pdb:6UKU|rcsb pdb:6UKV|rcsb pdb:6UKW|rcsb pdb:6UKX|rcsb pdb:6UKY|rcsb pdb:6UKZ|rcsb pdb:6UL0|rcsb pdb:6VEL|rcsb pdb:6VW2|rcsb pdb:7LTO|reactome:R-SCE-3065676|reactome:R-SCE-3065678|reactome:R-SCE-3065679|reactome:R-SCE-3108214|reactome:R-SCE-3108232|reactome:R-SCE-3232118|reactome:R-SCE-3899300|reactome:R-SCE-4085377|reactome:R-SCE-4551638|reactome:R-SCE-4570464|reactome:R-SCE-4615885|reactome:R-SCE-9615933|dip:DIP-1364N|mint:Q12306|sgd:YDR510W(identity)	-	isoform-comment:Major isoform.	crc64:A2790DE7F315E1A7	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:HrcogLANB///4vkSYtZ7OtzOb2k9606	rogid:oFdVBxN9WlDXTM7oAnv+1vfcXFQ559292	intact-crc:E8493FEA99CF3FCF|rigid:HOaD121ckCVmS/vLXZOgjAJqeE8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:B0QYN7	uniprotkb:Q12306	intact:EBI-11525376|ensembl:ENSP00000384361	intact:EBI-17490|uniprotkb:D6VTD1|ensemblfungi:YDR510W	psi-mi:b0qyn7_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)	psi-mi:smt3_yeast(display_long)|uniprotkb:SMT3(gene name)|psi-mi:SMT3(display_short)|uniprotkb:D9719.15(orf name)|uniprotkb:YDR510W(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11537143|imex:IM-24995-1550	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_005255597.1|refseq:XP_005255598.1|refseq:XP_011520946.1|refseq:XP_011520947.1|ensembl:ENSG00000103275(gene)|ensembl:ENST00000402301(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0016740"(transferase activity)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|entrezgene/locuslink:7329(identity)	refseq:NP_010798.1|sgd:S000002918|ensemblfungi:YDR510W(gene)|ensemblfungi:YDR510W_mRNA(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005940"(septin ring)|go:"GO:0016925"(protein sumoylation)|go:"GO:0031386"(protein tag)|go:"GO:0042802"(identical protein binding)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR022617|interpro:IPR029071|rcsb pdb:1EUV|rcsb pdb:1L2N|rcsb pdb:2EKE|rcsb pdb:3PGE|rcsb pdb:3QHT|rcsb pdb:3TIX|rcsb pdb:3UF8|rcsb pdb:3UQA|rcsb pdb:3UQB|rcsb pdb:3V60|rcsb pdb:3V61|rcsb pdb:3V62|rcsb pdb:3VAW|rcsb pdb:4FN2|rcsb pdb:4G50|rcsb pdb:4GGQ|rcsb pdb:4GIV|rcsb pdb:5D6J|rcsb pdb:5JNE|rcsb pdb:5KLX|rcsb pdb:5V8T|rcsb pdb:5YC2|rcsb pdb:5YCA|rcsb pdb:6CFP|rcsb pdb:6P81|rcsb pdb:6Q2S|rcsb pdb:6RPQ|rcsb pdb:6UKM|rcsb pdb:6UKU|rcsb pdb:6UKV|rcsb pdb:6UKW|rcsb pdb:6UKX|rcsb pdb:6UKY|rcsb pdb:6UKZ|rcsb pdb:6UL0|rcsb pdb:6VEL|rcsb pdb:6VW2|rcsb pdb:7LTO|reactome:R-SCE-3065676|reactome:R-SCE-3065678|reactome:R-SCE-3065679|reactome:R-SCE-3108214|reactome:R-SCE-3108232|reactome:R-SCE-3232118|reactome:R-SCE-3899300|reactome:R-SCE-4085377|reactome:R-SCE-4551638|reactome:R-SCE-4570464|reactome:R-SCE-4615885|reactome:R-SCE-9615933|dip:DIP-1364N|mint:Q12306|sgd:YDR510W(identity)	-	-	crc64:A2790DE7F315E1A7	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:zMqQOA+nnCUquTIxAUwemkElTYI9606	rogid:oFdVBxN9WlDXTM7oAnv+1vfcXFQ559292	intact-crc:6F86747368FD77B1|rigid:Ep+5f35Rf6pE50RcV2OoAY+y16Q	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9Y2D8	uniprotkb:Q12259	intact:EBI-2212028|uniprotkb:B4DFE3|uniprotkb:J3KR02|uniprotkb:A8K8W0|uniprotkb:D3DT13|uniprotkb:Q6P2P8|uniprotkb:Q6ULS1|uniprotkb:Q7L168|uniprotkb:Q9UIX0|intact:EBI-10964529|ensembl:ENSP00000340279	intact:EBI-30776|uniprotkb:D6VYA8|ensemblfungi:YLR108C	psi-mi:adip_human(display_long)|uniprotkb:SSX2IP(gene name)|psi-mi:SSX2IP(display_short)|uniprotkb:KIAA0923(gene name synonym)|uniprotkb:Afadin DIL domain-interacting protein(gene name synonym)|uniprotkb:SSX2-interacting protein(gene name synonym)	psi-mi:yl108_yeast(display_long)|uniprotkb:L2913(orf name)|uniprotkb:YLR108C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11537134|imex:IM-24995-1549	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011538912.1|refseq:NP_001159765.1|refseq:NP_001159766.1|refseq:NP_001159767.1|refseq:NP_001159889.1|refseq:NP_054740.3|refseq:XP_005270484.1|refseq:XP_005270485.1|refseq:XP_006710394.1|refseq:XP_016855723.1|ensembl:ENSG00000117155(gene)|ensembl:ENST00000342203(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005912"(adherens junction)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031252"(cell leading edge)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0035735"(intraciliary transport involved in cilium assembly)|go:"GO:0036064"(ciliary basal body)|go:"GO:0060271"(cilium assembly)|go:"GO:2000145"(regulation of cell motility)|interpro:IPR021622|mint:Q9Y2D8|entrezgene/locuslink:117178(identity)	refseq:NP_013209.1|sgd:S000004098|dip:DIP-4075N|ensemblfungi:YLR108C(gene)|ensemblfungi:YLR108C_mRNA(transcript)|go:"GO:0005634"(nucleus)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|sgd:YLR108C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:E0VeMRF9SrpQKSJFP01XEbMjeF89606	rogid:CzknxXhhvgMp3J0/oi197EgZ05U559292	intact-crc:C2F6CB5BD161B62E|rigid:1VHJ2RXiv00qeKbkVSavFpLhMM0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12259	uniprotkb:Q9UJV3-2	intact:EBI-30776|uniprotkb:D6VYA8|ensemblfungi:YLR108C	intact:EBI-10172526|ensembl:ENSP00000413976	psi-mi:yl108_yeast(display_long)|uniprotkb:L2913(orf name)|uniprotkb:YLR108C(locus name)	psi-mi:q9ujv3-2(display_long)|uniprotkb:RING-type E3 ubiquitin transferase MID2(gene name synonym)|uniprotkb:FXY2(gene name synonym)|uniprotkb:Midin-2(gene name synonym)|uniprotkb:Midline defect 2(gene name synonym)|uniprotkb:Midline-2(gene name synonym)|uniprotkb:RING finger protein 60(gene name synonym)|uniprotkb:RNF60(gene name synonym)|uniprotkb:TRIM1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 1(gene name synonym)|uniprotkb:MID2(gene name)|psi-mi:MID2(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11537123|imex:IM-24995-1548	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013209.1|sgd:S000004098|dip:DIP-4075N|ensemblfungi:YLR108C(gene)|ensemblfungi:YLR108C_mRNA(transcript)|go:"GO:0005634"(nucleus)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|sgd:YLR108C(identity)	intact:EBI-751983(isoform-parent)|uniprotkb:Q9UJV3-2(isoform-parent)|ensembl:ENSG00000080561(gene)|ensembl:ENST00000443968(transcript)|entrezgene/locuslink:11043(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:CzknxXhhvgMp3J0/oi197EgZ05U559292	rogid:/FJ+V2H7SaWon7caUWkEkmHFVxQ9606	intact-crc:31E6392328064901|rigid:a7+6SPKWP0N9Pw7PFvF9AgHEh4w	false	-	sufficient binding region:21-705	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12259	uniprotkb:Q9P209	intact:EBI-30776|uniprotkb:D6VYA8|ensemblfungi:YLR108C	intact:EBI-739498|uniprotkb:Q9BV03|uniprotkb:Q9BWM3|uniprotkb:Q9NVR4|uniprotkb:B4DR26|ensembl:ENSP00000264935	psi-mi:yl108_yeast(display_long)|uniprotkb:L2913(orf name)|uniprotkb:YLR108C(locus name)	psi-mi:cep72_human(display_long)|uniprotkb:CEP72(gene name)|psi-mi:CEP72(display_short)|uniprotkb:KIAA1519(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11537112|imex:IM-24995-1547	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013209.1|sgd:S000004098|dip:DIP-4075N|ensemblfungi:YLR108C(gene)|ensemblfungi:YLR108C_mRNA(transcript)|go:"GO:0005634"(nucleus)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|sgd:YLR108C(identity)	refseq:NP_060610.2|ensembl:ENSG00000112877(gene)|ensembl:ENST00000264935(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007051"(spindle organization)|go:"GO:0007099"(centriole replication)|go:"GO:0033566"(gamma-tubulin complex localization)|go:"GO:0034451"(centriolar satellite)|go:"GO:1904779"(regulation of protein localization to centrosome)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR003603(U2A'/phosphoprotein 32 family A, C-terminal)|interpro:IPR032675|interpro:IPR040146|mint:Q9P209|reactome:R-HSA-2565942|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|refseq:XP_011512365.1|dip:DIP-54272N|entrezgene/locuslink:55722(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:CzknxXhhvgMp3J0/oi197EgZ05U559292	rogid:c00WdgE2iudiQUz3kXNZL5d0nuQ9606	intact-crc:1DD920FA25DF40B8|rigid:ONT4emawE0Sz85EvUQeNZ2+b7Hg	false	-	sufficient binding region:190-647	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9NWS6	uniprotkb:Q12259	intact:EBI-8638992|uniprotkb:B4DY02|ensembl:ENSP00000216214|ensembl:ENSP00000395892|intact:MINT-8162875|uniprotkb:Q5TII5|uniprotkb:B3KWG4|uniprotkb:Q96CY3	intact:EBI-30776|uniprotkb:D6VYA8|ensemblfungi:YLR108C	psi-mi:f118a_human(display_long)|uniprotkb:FAM118A(gene name)|psi-mi:FAM118A(display_short)|uniprotkb:C22orf8(gene name synonym)	psi-mi:yl108_yeast(display_long)|uniprotkb:L2913(orf name)|uniprotkb:YLR108C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11537103|imex:IM-24995-1546	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000100376(gene)|ensembl:ENST00000216214(transcript)|ensembl:ENST00000441876(transcript)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|interpro:IPR033353|interpro:IPR038916|interpro:IPR039444|refseq:NP_060381.2|refseq:NP_001098065.1|entrezgene/locuslink:55007(identity)	refseq:NP_013209.1|sgd:S000004098|dip:DIP-4075N|ensemblfungi:YLR108C(gene)|ensemblfungi:YLR108C_mRNA(transcript)|go:"GO:0005634"(nucleus)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|sgd:YLR108C(identity)	-	comment:mint	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:zZMOyeZwAeoDNLBQ9EKYRw4+0BM9606	rogid:CzknxXhhvgMp3J0/oi197EgZ05U559292	intact-crc:4FCC0F83A4E83052|rigid:T1dDPKLlQd2I0aehmcKfvO0ceZU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9NVV9	uniprotkb:Q12259	intact:EBI-741515|uniprotkb:Q53FQ1|uniprotkb:Q6IA99|ensembl:ENSP00000254250|uniprotkb:A6NCB6|uniprotkb:D3DSY5|uniprotkb:H9KV49	intact:EBI-30776|uniprotkb:D6VYA8|ensemblfungi:YLR108C	psi-mi:thap1_human(display_long)|uniprotkb:THAP1(gene name)|psi-mi:THAP1(display_short)	psi-mi:yl108_yeast(display_long)|uniprotkb:L2913(orf name)|uniprotkb:YLR108C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11537094|imex:IM-24995-1545	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060575.1|ensembl:ENSG00000131931(gene)|ensembl:ENST00000254250(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001650"(fibrillar center)|go:"GO:0001935"(endothelial cell proliferation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007049"(cell cycle)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016605"(PML body)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR006612(Zinc finger, C2CH-type)|interpro:IPR026516|interpro:IPR038441|mint:Q9NVV9|rcsb pdb:2JTG|rcsb pdb:2KO0|rcsb pdb:2L1G|refseq:NP_945354.1|entrezgene/locuslink:55145(identity)	refseq:NP_013209.1|sgd:S000004098|dip:DIP-4075N|ensemblfungi:YLR108C(gene)|ensemblfungi:YLR108C_mRNA(transcript)|go:"GO:0005634"(nucleus)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|sgd:YLR108C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:/KO90pu5tBnIVq9SMx1JYPXFCEQ9606	rogid:CzknxXhhvgMp3J0/oi197EgZ05U559292	intact-crc:4FB75FEEEA4E13F7|rigid:HPH0K7k7xwZtExAi0j4OHsry67o	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8N9N5-2	uniprotkb:Q12329	intact:EBI-11524452|ensembl:ENSP00000347125	intact:EBI-8571|uniprotkb:D6VSF3|ensemblfungi:YDR171W	psi-mi:q8n9n5-2(display_long)|uniprotkb:BANP(gene name)|psi-mi:BANP(display_short)|uniprotkb:BEN domain-containing protein 1(gene name synonym)|uniprotkb:BEND1(gene name synonym)|uniprotkb:Btg3-associated nuclear protein(gene name synonym)|uniprotkb:SMAR1(gene name synonym)|uniprotkb:Scaffold/matrix-associated region-1-binding protein(gene name synonym)	psi-mi:hsp42_yeast(display_long)|uniprotkb:HSP42(gene name)|psi-mi:HSP42(display_short)|uniprotkb:YDR171W(locus name)|uniprotkb:YD9395.04(orf name)|uniprotkb:42 kDa heat shock protein(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11537248|imex:IM-24995-1561	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000172530(gene)|ensembl:ENST00000355022(transcript)|intact:EBI-744695(isoform-parent)|uniprotkb:Q8N9N5-2(isoform-parent)|entrezgene/locuslink:54971(identity)	refseq:NP_010456.1|sgd:S000002578|mint:Q12329|dip:DIP-2515N|ensemblfungi:YDR171W(gene)|ensemblfungi:YDR171W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0009408"(response to heat)|go:"GO:0009651"(response to salt stress)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043621"(protein self-association)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0140311"(protein sequestering activity)|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR031107|sgd:YDR171W(identity)	-	-	crc64:DF353A76493E3CE6	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:ESe6iCAhvq+i57fQHz3rGyg6UOo9606	rogid:izvrv04fA3zcBqTeUeHD/erKGf4559292	intact-crc:37601560B16DC147|rigid:qfKsJw/YTjkS/vwRcAEuCJNyM8o	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8IYA8	uniprotkb:Q12329	intact:EBI-8638439|intact:EBI-28969497|ensembl:ENSP00000296449|ensembl:ENSP00000391788|ensembl:ENSP00000407837|uniprotkb:C9JJL0|uniprotkb:Q96LP7|intact:MINT-8162095|uniprotkb:Q05DG9	intact:EBI-8571|uniprotkb:D6VSF3|ensemblfungi:YDR171W	psi-mi:iho1_human(display_long)|uniprotkb:IHO1(gene name)|psi-mi:IHO1(display_short)|uniprotkb:CCDC36(gene name synonym)|uniprotkb:Cancer/testis antigen 74(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 36(gene name synonym)	psi-mi:hsp42_yeast(display_long)|uniprotkb:HSP42(gene name)|psi-mi:HSP42(display_short)|uniprotkb:YDR171W(locus name)|uniprotkb:YD9395.04(orf name)|uniprotkb:42 kDa heat shock protein(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11537237|imex:IM-24995-1560	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000296449|ensembl:ENST00000366429|ensembl:ENSP00000403700|ensembl:ENSP00000391788|ensembl:ENSP00000407837|ensembl:ENSG00000173421(gene)|ensembl:ENST00000296449(transcript)|ensembl:ENST00000438782(transcript)|ensembl:ENST00000452691(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0006310"(DNA recombination)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0042138"(meiotic DNA double-strand break formation)|go:"GO:0048477"(oogenesis)|go:"GO:0060629"(regulation of homologous chromosome segregation)|interpro:IPR031529|mint:Q8IYA8|refseq:XP_011531974.1|refseq:XP_011531975.1|refseq:NP_001128669.1|refseq:NP_835467.2|refseq:XP_006713187.1|entrezgene/locuslink:339834(identity)	refseq:NP_010456.1|sgd:S000002578|mint:Q12329|dip:DIP-2515N|ensemblfungi:YDR171W(gene)|ensemblfungi:YDR171W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0009408"(response to heat)|go:"GO:0009651"(response to salt stress)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043621"(protein self-association)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0140311"(protein sequestering activity)|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR031107|sgd:YDR171W(identity)	-	comment:mint	crc64:DF353A76493E3CE6	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:+TNQLExkhmC1NWqsE240Cx7zFVU9606	rogid:izvrv04fA3zcBqTeUeHD/erKGf4559292	intact-crc:E72280025F9BC42E|rigid:e2BgtnOteZXZbtFm3URi4h2shDM	false	sufficient binding region:11-594	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12329	uniprotkb:Q5T124-6	intact:EBI-8571|uniprotkb:D6VSF3|ensemblfungi:YDR171W	intact:EBI-11524408	psi-mi:hsp42_yeast(display_long)|uniprotkb:HSP42(gene name)|psi-mi:HSP42(display_short)|uniprotkb:YDR171W(locus name)|uniprotkb:YD9395.04(orf name)|uniprotkb:42 kDa heat shock protein(gene name synonym)	psi-mi:q5t124-6(display_long)|uniprotkb:UBXN11(gene name)|psi-mi:UBXN11(display_short)|uniprotkb:Colorectal tumor-associated antigen COA-1(gene name synonym)|uniprotkb:SOC(gene name synonym)|uniprotkb:Socius(gene name synonym)|uniprotkb:UBX domain-containing protein 5(gene name synonym)|uniprotkb:UBXD5(gene name synonym)|uniprotkb:PP2243(orf name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11537228|imex:IM-24995-1559	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010456.1|sgd:S000002578|mint:Q12329|dip:DIP-2515N|ensemblfungi:YDR171W(gene)|ensemblfungi:YDR171W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0009408"(response to heat)|go:"GO:0009651"(response to salt stress)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043621"(protein self-association)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0140311"(protein sequestering activity)|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR031107|sgd:YDR171W(identity)	intact:EBI-746004(isoform-parent)|uniprotkb:Q5T124-6(isoform-parent)|entrezgene/locuslink:91544(identity)	-	crc64:DF353A76493E3CE6	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:izvrv04fA3zcBqTeUeHD/erKGf4559292	rogid:1YSjG/p2ihcjl4P8KdPCaX2HxiY9606	intact-crc:682D223835B3F894|rigid:6C7uPE50u2e0rlNYgtHYRIEau/I	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O15162	uniprotkb:Q12329	intact:EBI-740019|ensembl:ENSP00000345494|uniprotkb:B2R8H8|uniprotkb:B4DTE8	intact:EBI-8571|uniprotkb:D6VSF3|ensemblfungi:YDR171W	psi-mi:pls1_human(display_long)|uniprotkb:PLSCR1(gene name)|psi-mi:PLSCR1(display_short)|uniprotkb:"Ca(2+)-dependent phospholipid scramblase 1"(gene name synonym)|uniprotkb:Erythrocyte phospholipid scramblase(gene name synonym)|uniprotkb:MmTRA1b(gene name synonym)|uniprotkb:"Mg(2+)-dependent nuclease"(gene name synonym)	psi-mi:hsp42_yeast(display_long)|uniprotkb:HSP42(gene name)|psi-mi:HSP42(display_short)|uniprotkb:YDR171W(locus name)|uniprotkb:YD9395.04(orf name)|uniprotkb:42 kDa heat shock protein(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11537219|imex:IM-24995-1558	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000188313(gene)|ensembl:ENST00000342435(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001618"(virus receptor activity)|go:"GO:0003677"(DNA binding)|go:"GO:0004518"(nuclease activity)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006659"(phosphatidylserine biosynthetic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0006953"(acute-phase response)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010288"(response to lead ion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0017121"(plasma membrane phospholipid scrambling)|go:"GO:0017124"(SH3 domain binding)|ensembl:ENSP00000345494|ensembl:ENST00000448787|ensembl:ENSP00000411675|refseq:NP_066928.1|go:"GO:0017128"(phospholipid scramblase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030168"(platelet activation)|go:"GO:0032791"(lead ion binding)|go:"GO:0033003"(regulation of mast cell activation)|go:"GO:0035456"(response to interferon-beta)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0045340"(mercury ion binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0051607"(defense response to virus)|go:"GO:0060368"(regulation of Fc receptor mediated stimulatory signaling pathway)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070782"(phosphatidylserine exposure on apoptotic cell surface)|go:"GO:1905820"(positive regulation of chromosome separation)|go:"GO:2000373"("positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity")|interpro:IPR005552(Scramblase)|mint:O15162|rcsb pdb:1Y2A|refseq:XP_011511209.1|refseq:XP_011511206.1|refseq:XP_005247595.1|refseq:XP_011511208.1|refseq:XP_016862118.1|entrezgene/locuslink:5359(identity)	refseq:NP_010456.1|sgd:S000002578|mint:Q12329|dip:DIP-2515N|ensemblfungi:YDR171W(gene)|ensemblfungi:YDR171W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0009408"(response to heat)|go:"GO:0009651"(response to salt stress)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043621"(protein self-association)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0140311"(protein sequestering activity)|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR031107|sgd:YDR171W(identity)	-	-	crc64:DF353A76493E3CE6	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:XudfvUkrZbB28t9tpFkokgnDFGc9606	rogid:izvrv04fA3zcBqTeUeHD/erKGf4559292	intact-crc:21215BD57B941841|rigid:DQ2v1ZTTgw4SkxNTVvVZCZA3UG0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:A0A024R0Y4	uniprotkb:Q12329	intact:EBI-11523730|ensembl:ENSP00000477709|ensembl:ENSP00000478363|ensembl:ENSP00000481091	intact:EBI-8571|uniprotkb:D6VSF3|ensemblfungi:YDR171W	psi-mi:a0a024r0y4_human(display_long)|uniprotkb:TADA2A(gene name)|psi-mi:TADA2A(display_short)|uniprotkb:TADA2L(gene name synonym)|uniprotkb:hCG_28187(orf name)	psi-mi:hsp42_yeast(display_long)|uniprotkb:HSP42(gene name)|psi-mi:HSP42(display_short)|uniprotkb:YDR171W(locus name)|uniprotkb:YD9395.04(orf name)|uniprotkb:42 kDa heat shock protein(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11537210|imex:IM-24995-1557	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001159577.2|refseq:NP_001479.4|ensembl:ENSG00000276234(gene)|ensembl:ENST00000612272(transcript)|ensembl:ENST00000615182(transcript)|ensembl:ENST00000620628(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031063"(regulation of histone deacetylation)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0035065"(regulation of histone acetylation)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090043"(regulation of tubulin deacetylation)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016827(Transcriptional adaptor 2)|interpro:IPR017884|interpro:IPR017930|interpro:IPR036388|interpro:IPR041983|interpro:IPR043145|entrezgene/locuslink:6871(identity)	refseq:NP_010456.1|sgd:S000002578|mint:Q12329|dip:DIP-2515N|ensemblfungi:YDR171W(gene)|ensemblfungi:YDR171W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0009408"(response to heat)|go:"GO:0009651"(response to salt stress)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043621"(protein self-association)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0140311"(protein sequestering activity)|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR031107|sgd:YDR171W(identity)	-	-	crc64:DF353A76493E3CE6	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:IGh7vC68gMLe+tAVGM4gc0rzc6Y9606	rogid:izvrv04fA3zcBqTeUeHD/erKGf4559292	intact-crc:0F0EA57271A8FE96|rigid:AhFQF+UySGeUroxxo6tJBS1uzRk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12318	uniprotkb:Q15911-2	intact:EBI-37340|uniprotkb:D6VZ12|ensemblfungi:YLR376C	intact:EBI-10237226|ensembl:ENSP00000438926	psi-mi:psy3_yeast(display_long)|uniprotkb:PSY3(gene name)|psi-mi:PSY3(display_short)|uniprotkb:L8039.17(orf name)|uniprotkb:YLR376C(locus name)	psi-mi:q15911-2(display_long)|uniprotkb:ZFHX3(gene name)|psi-mi:ZFHX3(display_short)|uniprotkb:AT motif-binding factor 1(gene name synonym)|uniprotkb:AT-binding transcription factor 1(gene name synonym)|uniprotkb:ATBF1(gene name synonym)|uniprotkb:Alpha-fetoprotein enhancer-binding protein(gene name synonym)|uniprotkb:Zinc finger homeodomain protein 3(gene name synonym)|uniprotkb:C16orf47(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11537199|imex:IM-24995-1556	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000004368|refseq:NP_013480.1|dip:DIP-1903N|ensemblfungi:YLR376C(gene)|ensemblfungi:YLR376C_mRNA(transcript)|go:"GO:0000725"(recombinational repair)|go:"GO:0000730"(DNA recombinase assembly)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0035861"(site of double-strand break)|go:"GO:0070987"(error-free translesion synthesis)|go:"GO:0097196"(Shu complex)|interpro:IPR027417|interpro:IPR031779|rcsb pdb:3VU9|rcsb pdb:4DT1|rcsb pdb:4EQ6|rcsb pdb:5XYN|sgd:YLR376C(identity)	intact:EBI-2849611(isoform-parent)|uniprotkb:Q15911-2(isoform-parent)|ensembl:ENST00000397992(transcript)|ensembl:ENSG00000140836(gene)|entrezgene/locuslink:463(identity)	-	crc64:B652FD8113EB4C12	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:SlNKYcljv2UVV8YxX5/kVQJV/rU559292	rogid:2SwbWXRFfxKEHEbo/SlMGw8/hPU9606	intact-crc:EFF19FD0EB36B45A|rigid:lt0Ppo9sfiGTtecbUmGmPV8ZC3U	false	-	sufficient binding region:1-886	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12318	uniprotkb:O95751	intact:EBI-37340|uniprotkb:D6VZ12|ensemblfungi:YLR376C	intact:EBI-740738|ensembl:ENSP00000359557|uniprotkb:Q6IAR6	psi-mi:psy3_yeast(display_long)|uniprotkb:PSY3(gene name)|psi-mi:PSY3(display_short)|uniprotkb:L8039.17(orf name)|uniprotkb:YLR376C(locus name)	psi-mi:ldoc1_human(display_long)|uniprotkb:Leucine zipper protein down-regulated in cancer cells(gene name synonym)|uniprotkb:LDOC1(gene name)|psi-mi:LDOC1(display_short)|uniprotkb:BCUR1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11537190|imex:IM-24995-1555	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000004368|refseq:NP_013480.1|dip:DIP-1903N|ensemblfungi:YLR376C(gene)|ensemblfungi:YLR376C_mRNA(transcript)|go:"GO:0000725"(recombinational repair)|go:"GO:0000730"(DNA recombinase assembly)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0035861"(site of double-strand break)|go:"GO:0070987"(error-free translesion synthesis)|go:"GO:0097196"(Shu complex)|interpro:IPR027417|interpro:IPR031779|rcsb pdb:3VU9|rcsb pdb:4DT1|rcsb pdb:4EQ6|rcsb pdb:5XYN|sgd:YLR376C(identity)	refseq:NP_036449.1|ensembl:ENSG00000182195(gene)|ensembl:ENST00000370526(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071225"(cellular response to muramyl dipeptide)|interpro:IPR032549|interpro:IPR032567|entrezgene/locuslink:23641(identity)	-	crc64:B652FD8113EB4C12	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:SlNKYcljv2UVV8YxX5/kVQJV/rU559292	rogid:Ediu0oNiZ/+YVY8l3fNdgP5A+v09606	intact-crc:1AF585DB621DFFEA|rigid:gF21nbpzGaPczRzexQEg3ER3Bnw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12318	uniprotkb:Q08379	intact:EBI-37340|uniprotkb:D6VZ12|ensemblfungi:YLR376C	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	psi-mi:psy3_yeast(display_long)|uniprotkb:PSY3(gene name)|psi-mi:PSY3(display_short)|uniprotkb:L8039.17(orf name)|uniprotkb:YLR376C(locus name)	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11537179|imex:IM-24995-1554	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000004368|refseq:NP_013480.1|dip:DIP-1903N|ensemblfungi:YLR376C(gene)|ensemblfungi:YLR376C_mRNA(transcript)|go:"GO:0000725"(recombinational repair)|go:"GO:0000730"(DNA recombinase assembly)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0035861"(site of double-strand break)|go:"GO:0070987"(error-free translesion synthesis)|go:"GO:0097196"(Shu complex)|interpro:IPR027417|interpro:IPR031779|rcsb pdb:3VU9|rcsb pdb:4DT1|rcsb pdb:4EQ6|rcsb pdb:5XYN|sgd:YLR376C(identity)	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N|entrezgene/locuslink:2801(identity)	-	crc64:B652FD8113EB4C12	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2017/05/26	rogid:SlNKYcljv2UVV8YxX5/kVQJV/rU559292	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	intact-crc:42D03186A2E91AC6|rigid:Lplc7YMVYs7v4PVL6csSKfimvNM	false	-	sufficient binding region:383-1002	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96BA8	uniprotkb:Q12382	intact:EBI-6942903|ensembl:ENSP00000481956|intact:MINT-268046|intact:MINT-8162577|uniprotkb:Q8N2D5|uniprotkb:Q96CP0	intact:EBI-36644|uniprotkb:D6W310|ensemblfungi:YOR311C	psi-mi:cr3l1_human(display_long)|uniprotkb:CREB3L1(gene name)|psi-mi:CREB3L1(display_short)|uniprotkb:OASIS(gene name synonym)|uniprotkb:PSEC0238(orf name)|uniprotkb:Old astrocyte specifically-induced substance(gene name synonym)	psi-mi:dgk1_yeast(display_long)|uniprotkb:High-copy suppressor of SLY1 defect protein 1(gene name synonym)|uniprotkb:DGK1(gene name)|psi-mi:DGK1(display_short)|uniprotkb:HSD1(gene name synonym)|uniprotkb:O6111(orf name)|uniprotkb:YOR311C(locus name)|uniprotkb:Diglyceride kinase 1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11537340|imex:IM-24995-1571	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157613(gene)|ensembl:ENST00000621158(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0070278"(extracellular matrix constituent secretion)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029805|mint:Q96BA8|reactome:R-HSA-8874211|refseq:NP_443086.1|entrezgene/locuslink:90993(identity)	sgd:S000005838|refseq:NP_014956.3|dip:DIP-5021N|ensemblfungi:YOR311C(gene)|ensemblfungi:YOR311C_mRNA(transcript)|go:"GO:0004143"(diacylglycerol kinase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006654"(phosphatidic acid biosynthetic process)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:2001210"(regulation of isopentenyl diphosphate biosynthetic process, mevalonate pathway)|interpro:IPR037997|sgd:YOR311C(identity)	-	comment:mint|function:"Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE"	crc64:F8A0EE6F1018025B	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:sMWUFmBeBBCO+T0Y2CuB/un1lBg9606	rogid:/QKdWOYiwS8WsUTob40AL05Q9Hw559292	intact-crc:C3C7B4E137373728|rigid:E1chp7hW5Yli2a5YmWKc7tCZS/4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8N6L0	uniprotkb:Q12382	intact:EBI-749265|uniprotkb:Q96MC3|ensembl:ENSP00000404220	intact:EBI-36644|uniprotkb:D6W310|ensemblfungi:YOR311C	psi-mi:kash5_human(display_long)|uniprotkb:KASH5(gene name)|psi-mi:KASH5(display_short)|uniprotkb:CCDC155(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 155(gene name synonym)|uniprotkb:KASH domain-containing protein 5(gene name synonym)	psi-mi:dgk1_yeast(display_long)|uniprotkb:High-copy suppressor of SLY1 defect protein 1(gene name synonym)|uniprotkb:DGK1(gene name)|psi-mi:DGK1(display_short)|uniprotkb:HSD1(gene name synonym)|uniprotkb:O6111(orf name)|uniprotkb:YOR311C(locus name)|uniprotkb:Diglyceride kinase 1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11537331|imex:IM-24995-1570	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_653289.3|ensembl:ENSG00000161609(gene)|ensembl:ENST00000447857(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034397"(telomere localization)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051225"(spindle assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0090172"(microtubule cytoskeleton organization involved in homologous chromosome segregation)|go:"GO:0090220"(chromosome localization to nuclear envelope involved in homologous chromosome segregation)|go:"GO:0090619"(meiotic spindle pole)|interpro:IPR011992(EF-Hand type)|interpro:IPR028168|interpro:IPR028170|interpro:IPR039508|mint:Q8N6L0|rcsb pdb:6R2I|rcsb pdb:6WMF|entrezgene/locuslink:147872(identity)	sgd:S000005838|refseq:NP_014956.3|dip:DIP-5021N|ensemblfungi:YOR311C(gene)|ensemblfungi:YOR311C_mRNA(transcript)|go:"GO:0004143"(diacylglycerol kinase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006654"(phosphatidic acid biosynthetic process)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:2001210"(regulation of isopentenyl diphosphate biosynthetic process, mevalonate pathway)|interpro:IPR037997|sgd:YOR311C(identity)	-	-	crc64:F8A0EE6F1018025B	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Wl9L7AcvDHCZuKjYLn8QgGIbZTc9606	rogid:/QKdWOYiwS8WsUTob40AL05Q9Hw559292	intact-crc:2E2B0622C42C087E|rigid:8uCgzyVNpSfPr0geC3hoJ0hbNeA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12380	uniprotkb:P49760-3	intact:EBI-2664|uniprotkb:D6W3M0|ensemblfungi:YPL149W	intact:EBI-11535445|ensembl:ENSP00000354856|ensembl:ENSP00000459461	psi-mi:atg5_yeast(display_long)|uniprotkb:ATG5(gene name)|psi-mi:ATG5(display_short)|uniprotkb:APG5(gene name synonym)|uniprotkb:YPL149W(locus name)|uniprotkb:P2601(orf name)	psi-mi:p49760-3(display_long)|uniprotkb:CDC-like kinase 2(gene name synonym)|uniprotkb:CLK2(gene name)|psi-mi:CLK2(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11537322|imex:IM-24995-1569	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015176.1|sgd:S000006070|reactome:R-SCE-1632852|dip:DIP-1195N|reactome:R-SCE-8934903|ensemblfungi:YPL149W(gene)|ensemblfungi:YPL149W_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005634"(nucleus)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0006501"(C-terminal protein lipidation)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016020"(membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0016787"(hydrolase activity)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034274"(Atg12-Atg5-Atg16 complex)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044804"(autophagy of nucleus)|go:"GO:0044805"(late nucleophagy)|go:"GO:0061908"(phagophore)|go:"GO:0061912"(selective autophagy)|go:"GO:0120095"(vacuole-isolation membrane contact site)|go:"GO:0140355"(cargo receptor ligand activity)|interpro:IPR007239(Autophagy protein 5)|interpro:IPR042526|interpro:IPR042527|rcsb pdb:2DYM|rcsb pdb:2DYO|rcsb pdb:3W1S|sgd:YPL149W(identity)	intact:EBI-750020(isoform-parent)|ensembl:ENSG00000176444(gene)|ensembl:ENSG00000261893(gene)|ensembl:ENST00000361168(transcript)|ensembl:ENST00000572269(transcript)|uniprotkb:P49760-3(isoform-parent)|entrezgene/locuslink:1196(identity)	-	crc64:BE513A631DEAA0A1	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:PMSbzCApcY0S518yzmdDm3bPY74559292	rogid:wFw4PjPFbFOw5k9Fqay3nAen8ZI9606	intact-crc:AE6BBA232F8C015F|rigid:5tumTh+hsOZZ9hC+VgM3hQfs+Qg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8WZ19	uniprotkb:Q12354	intact:EBI-742916|ensembl:ENSP00000311202|ensembl:ENSP00000455785|uniprotkb:Q96P93|uniprotkb:Q96SA1|uniprotkb:A8K0R5	intact:EBI-37732|uniprotkb:D6VYB6|ensemblfungi:YLR118C	psi-mi:bacd1_human(display_long)|uniprotkb:Polymerase delta-interacting protein 1(gene name synonym)|uniprotkb:TNFAIP1-like protein(gene name synonym)|uniprotkb:KCTD13(gene name)|psi-mi:KCTD13(display_short)|uniprotkb:PDIP1(gene name synonym)|uniprotkb:POLDIP1(gene name synonym)|uniprotkb:FKSG86(orf name)|uniprotkb:PP6832(orf name)|uniprotkb:BACURD1(gene name synonym)|uniprotkb:BTB/POZ domain-containing protein KCTD13(gene name synonym)	psi-mi:apth1_yeast(display_long)|uniprotkb:L2955(orf name)|uniprotkb:YLR118C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11537313|imex:IM-24995-1568	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_849194.1|ensembl:ENSG00000174943(gene)|ensembl:ENST00000308768(transcript)|ensembl:ENST00000568000(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016477"(cell migration)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0043149"(stress fiber assembly)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0050806"(positive regulation of synaptic transmission)|go:"GO:0051260"(protein homooligomerization)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR003131(Potassium channel, voltage dependent, Kv,  tetramerisation)|interpro:IPR011333(BTB/POZ fold)|mint:Q8WZ19|rcsb pdb:4UIJ|reactome:R-HSA-9696264|reactome:R-HSA-9696270|entrezgene/locuslink:253980(identity)	refseq:NP_013219.1|sgd:S000004108|reactome:R-SCE-203615|dip:DIP-2830N|reactome:R-SCE-9648002|ensemblfungi:YLR118C(gene)|ensemblfungi:YLR118C_mRNA(transcript)|go:"GO:0002084"(protein depalmitoylation)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0008474"("palmitoyl-(protein) hydrolase activity")|go:"GO:0035601"(protein deacylation)|go:"GO:0052689"(carboxylic ester hydrolase activity)|interpro:IPR003140(Phospholipase/carboxylesterase)|interpro:IPR029058|sgd:YLR118C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:hAH5yJEoda0H1anmnSXWHO0o1ZM9606	rogid:z4WO9062CHwiLV2c1/+N6zn0AEE559292	intact-crc:140C6B89920864EB|rigid:sbZUfm+kDbyU4Pw91svZXTROBu0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q5JST6	uniprotkb:Q12354	intact:EBI-2349927|uniprotkb:Q9H653|uniprotkb:Q5JST8|uniprotkb:Q68DK4|uniprotkb:Q8NEI0|intact:EBI-28971886|ensembl:ENSP00000404232	intact:EBI-37732|uniprotkb:D6VYB6|ensemblfungi:YLR118C	psi-mi:efhc2_human(display_long)|uniprotkb:EFHC2(gene name)|psi-mi:EFHC2(display_short)	psi-mi:apth1_yeast(display_long)|uniprotkb:L2955(orf name)|uniprotkb:YLR118C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11537304|imex:IM-24995-1567	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000404232|refseq:NP_079460.2|ensembl:ENSG00000183690(gene)|ensembl:ENST00000420999(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005930"(axoneme)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0060285"(cilium-dependent cell motility)|go:"GO:0072686"(mitotic spindle)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR006602(Region of unknown function DM10)|interpro:IPR011992(EF-Hand type)|interpro:IPR040193|rcsb pdb:2Z13|rcsb pdb:2Z14|entrezgene/locuslink:80258(identity)	refseq:NP_013219.1|sgd:S000004108|reactome:R-SCE-203615|dip:DIP-2830N|reactome:R-SCE-9648002|ensemblfungi:YLR118C(gene)|ensemblfungi:YLR118C_mRNA(transcript)|go:"GO:0002084"(protein depalmitoylation)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0008474"("palmitoyl-(protein) hydrolase activity")|go:"GO:0035601"(protein deacylation)|go:"GO:0052689"(carboxylic ester hydrolase activity)|interpro:IPR003140(Phospholipase/carboxylesterase)|interpro:IPR029058|sgd:YLR118C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:O1XriQSkLcYkk7H7AlanQ1FKIBY9606	rogid:z4WO9062CHwiLV2c1/+N6zn0AEE559292	intact-crc:CAABE663D7AD12FA|rigid:ERsx6GWfLx/Ylwy0BOdDl5+83hc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q13137	uniprotkb:Q12342	intact:EBI-739580|uniprotkb:B4DDC4|uniprotkb:E7ENK0|uniprotkb:Q53FQ5|uniprotkb:Q53HB5|uniprotkb:Q6IBN9|uniprotkb:Q9BTF7|uniprotkb:B2RBT0|ensembl:ENSP00000258947|uniprotkb:B4E0C0|uniprotkb:E7ETP5|uniprotkb:B4DDT4|uniprotkb:B4DP36|uniprotkb:E9PBE5	intact:EBI-38872|uniprotkb:D6VRK2|ensemblfungi:YDL146W	psi-mi:caco2_human(display_long)|uniprotkb:CALCOCO2(gene name)|psi-mi:CALCOCO2(display_short)|uniprotkb:NDP52(gene name synonym)|uniprotkb:Nuclear domain 10 protein NDP52(gene name synonym)|uniprotkb:Antigen nuclear dot 52 kDa protein(gene name synonym)|uniprotkb:Nuclear dot protein 52(gene name synonym)	psi-mi:ldb17_yeast(display_long)|uniprotkb:Low dye-binding protein 17(gene name synonym)|uniprotkb:LDB17(gene name)|psi-mi:LDB17(display_short)|uniprotkb:D1575(orf name)|uniprotkb:YDL146W(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11537295|imex:IM-24995-1566	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001248319.1|refseq:NP_001248320.1|refseq:NP_001248322.1|refseq:NP_005822.1|ensembl:ENSG00000136436(gene)|ensembl:ENST00000258947(transcript)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016032"(viral process)|go:"GO:0016605"(PML body)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0098792"(xenophagy)|go:"GO:1901098"(positive regulation of autophagosome maturation)|interpro:IPR041611|interpro:IPR041641|mint:Q13137|rcsb pdb:2MXP|rcsb pdb:3VVV|rcsb pdb:3VVW|rcsb pdb:4GXL|rcsb pdb:4HAN|rcsb pdb:4XKL|rcsb pdb:5AAQ|rcsb pdb:5Z7A|rcsb pdb:5Z7L|refseq:NP_001248324.1|dip:DIP-57534N|entrezgene/locuslink:10241(identity)	refseq:NP_010135.1|sgd:S000002305|dip:DIP-1803N|ensemblfungi:YDL146W(gene)|ensemblfungi:YDL146W_mRNA(transcript)|go:"GO:0000147"(actin cortical patch assembly)|go:"GO:0005737"(cytoplasm)|go:"GO:0005933"(cellular bud)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006897"(endocytosis)|go:"GO:0017022"(myosin binding)|go:"GO:0030479"(actin cortical patch)|go:"GO:0051666"(actin cortical patch localization)|go:"GO:0071933"(Arp2/3 complex binding)|interpro:IPR018556|interpro:IPR030125|sgd:YDL146W(identity)	-	crc64:609B121DA1A9DCB8	crc64:608DED6598F054BD	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:N/GPJUGBK+Dh5Cg+csmafphuo9M9606	rogid:o1oe+zL8FJ90xm43hCM9A7lGCjI559292	intact-crc:8F9818E72F57D2EF|rigid:VVJMZbTKuZ9FvwMTkTANwYJt7ww	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9C040	uniprotkb:Q12341	intact:EBI-749840|uniprotkb:O60272|uniprotkb:Q9BSI9|uniprotkb:Q9UFZ1|ensembl:ENSP00000415812|ensembl:ENSP00000501586|ensembl:ENSP00000501612|ensembl:ENSP00000501652|ensembl:ENSP00000501662|ensembl:ENSP00000501792|ensembl:ENSP00000501822|ensembl:ENSP00000501951|ensembl:ENSP00000501994|ensembl:ENSP00000502089|ensembl:ENSP00000502114|ensembl:ENSP00000502159|ensembl:ENSP00000502273|ensembl:ENSP00000502348|ensembl:ENSP00000502356|ensembl:ENSP00000502519|ensembl:ENSP00000502543|ensembl:ENSP00000502676|uniprotkb:D3DP09	intact:EBI-8176|uniprotkb:Q6Q5I5|uniprotkb:D6W411|ensemblfungi:YPL001W	psi-mi:trim2_human(display_long)|uniprotkb:RING finger protein 86(gene name synonym)|uniprotkb:TRIM2(gene name)|psi-mi:TRIM2(display_short)|uniprotkb:KIAA0517(gene name synonym)|uniprotkb:RNF86(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM2(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase TRIM2(gene name synonym)	psi-mi:hat1_yeast(display_long)|uniprotkb:LPA16W(orf name)|uniprotkb:YP8132.12(orf name)|uniprotkb:HAT1(gene name)|psi-mi:HAT1(display_short)|uniprotkb:YPL001W(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11537286|imex:IM-24995-1565	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001123539.1|refseq:NP_056086.2|ensembl:ENST00000437508(transcript)|ensembl:ENST00000674874(transcript)|ensembl:ENST00000674876(transcript)|ensembl:ENSG00000109654(gene)|refseq:XP_016863433.1|refseq:XP_016863434.1|refseq:XP_016863437.1|refseq:XP_016863438.1|refseq:XP_016863439.1|refseq:XP_016863440.1|refseq:XP_016863441.1|ensembl:ENST00000674976(transcript)|ensembl:ENST00000675054(transcript)|ensembl:ENST00000675159(transcript)|ensembl:ENST00000675293(transcript)|ensembl:ENST00000675315(transcript)|ensembl:ENST00000675384(transcript)|ensembl:ENST00000675745(transcript)|ensembl:ENST00000675835(transcript)|ensembl:ENST00000676172(transcript)|ensembl:ENST00000676252(transcript)|ensembl:ENST00000676264(transcript)|ensembl:ENST00000676348(transcript)|ensembl:ENST00000676374(transcript)|ensembl:ENST00000676423(transcript)|ensembl:ENST00000676458(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017868|interpro:IPR017907|interpro:IPR027370|mint:Q9C040|rcsb pdb:7B2R|reactome:R-HSA-877300|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001258(NHL repeat)|interpro:IPR001298(Filamin/ABP280 repeat)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR013017(NHL repeat, subgroup)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|entrezgene/locuslink:23321(identity)	sgd:S000005922|refseq:NP_015324.1|mint:Q12341|dip:DIP-2362N|ensemblfungi:YPL001W(gene)|ensemblfungi:YPL001W_mRNA(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003682"(chromatin binding)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006348"|go:"GO:0010485"(H4 histone acetyltransferase activity)|go:"GO:0016573"(histone acetylation)|go:"GO:0042393"(histone binding)|go:"GO:0043967"(histone H4 acetylation)|interpro:IPR000182(GCN5-related N-acetyltransferase)|interpro:IPR013523(Histone acetyltransferase HAT1, C-terminal)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR017380(Histone acetyltransferase type B, catalytic subunit)|interpro:IPR019467|interpro:IPR037113|rcsb pdb:1BOB|rcsb pdb:4PSW|rcsb pdb:4PSX|reactome:R-SCE-3214847|sgd:YPL001W(identity)	-	-	crc64:8DECA134274413E6	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:vcyraMhX0YqrCi9PXhvlJ7QqhGs9606	rogid:IUMaZUpA1qs4/hc8K6ezZAIpQTY559292	intact-crc:908B3CFCF2F03130|rigid:IMZDvVUmODZSsGzO/6xoJIj8o9w	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12329	uniprotkb:Q99750	intact:EBI-8571|uniprotkb:D6VSF3|ensemblfungi:YDR171W	intact:EBI-724076|ensembl:ENSP00000230321|ensembl:ENSP00000362142	psi-mi:hsp42_yeast(display_long)|uniprotkb:HSP42(gene name)|psi-mi:HSP42(display_short)|uniprotkb:YDR171W(locus name)|uniprotkb:YD9395.04(orf name)|uniprotkb:42 kDa heat shock protein(gene name synonym)	psi-mi:mdfi_human(display_long)|uniprotkb:Myogenic repressor I-mf(gene name synonym)|uniprotkb:MDFI(gene name)|psi-mi:MDFI(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11537277|imex:IM-24995-1564	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010456.1|sgd:S000002578|mint:Q12329|dip:DIP-2515N|ensemblfungi:YDR171W(gene)|ensemblfungi:YDR171W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0009408"(response to heat)|go:"GO:0009651"(response to salt stress)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043621"(protein self-association)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0140311"(protein sequestering activity)|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR031107|sgd:YDR171W(identity)	refseq:NP_005577.1|ensembl:ENSG00000112559(gene)|ensembl:ENST00000230321(transcript)|ensembl:ENST00000373051(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR026134|mint:Q99750|refseq:NP_001287733.1|refseq:NP_001287734.1|refseq:NP_001287735.1|entrezgene/locuslink:4188(identity)	-	crc64:DF353A76493E3CE6	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:izvrv04fA3zcBqTeUeHD/erKGf4559292	rogid:V3vU0fihMOW18DMHAiDbuZ3asNU9606	intact-crc:177B2D9D4AA77B3A|rigid:1gAG+ma3vqbrFavwjVgrbasv7A8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12329	uniprotkb:Q96MA1	intact:EBI-8571|uniprotkb:D6VSF3|ensemblfungi:YDR171W	intact:EBI-954466|uniprotkb:Q96SD2|ensembl:ENSP00000360500	psi-mi:hsp42_yeast(display_long)|uniprotkb:HSP42(gene name)|psi-mi:HSP42(display_short)|uniprotkb:YDR171W(locus name)|uniprotkb:YD9395.04(orf name)|uniprotkb:42 kDa heat shock protein(gene name synonym)	psi-mi:dmrtb_human(display_long)|uniprotkb:DMRTB1(gene name)|psi-mi:DMRTB1(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11537266|imex:IM-24995-1563	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010456.1|sgd:S000002578|mint:Q12329|dip:DIP-2515N|ensemblfungi:YDR171W(gene)|ensemblfungi:YDR171W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0009408"(response to heat)|go:"GO:0009651"(response to salt stress)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043621"(protein self-association)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0140311"(protein sequestering activity)|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR031107|sgd:YDR171W(identity)	go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|ensembl:ENSG00000143006(gene)|ensembl:ENST00000371445(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007281"(germ cell development)|go:"GO:0007548"(sex differentiation)|go:"GO:0046872"(metal ion binding)|interpro:IPR001275(DM DNA-binding)|interpro:IPR026607|interpro:IPR036407|mint:Q96MA1|refseq:NP_149056.1|ensembl:ENSP00000360500|entrezgene/locuslink:63948(identity)	-	crc64:DF353A76493E3CE6	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:izvrv04fA3zcBqTeUeHD/erKGf4559292	rogid:GU1xgsv/Oyy91PEorOlxBqAvIzc9606	intact-crc:8FCECB78880291CA|rigid:uf8t2oK/UJIv8f9JHFrABaIU750	false	-	sufficient binding region:154-342	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12329	uniprotkb:Q96D09	intact:EBI-8571|uniprotkb:D6VSF3|ensemblfungi:YDR171W	intact:EBI-473189|ensembl:ENSP00000339057|ensembl:ENSP00000437394|ensembl:ENSP00000437872|ensembl:ENSP00000507692|ensembl:ENSP00000508139|uniprotkb:Q8NAB4|uniprotkb:D3DXA0	psi-mi:hsp42_yeast(display_long)|uniprotkb:HSP42(gene name)|psi-mi:HSP42(display_short)|uniprotkb:YDR171W(locus name)|uniprotkb:YD9395.04(orf name)|uniprotkb:42 kDa heat shock protein(gene name synonym)	psi-mi:gasp2_human(display_long)|uniprotkb:GPRASP2(gene name)|psi-mi:GPRASP2(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11537257|imex:IM-24995-1562	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010456.1|sgd:S000002578|mint:Q12329|dip:DIP-2515N|ensemblfungi:YDR171W(gene)|ensemblfungi:YDR171W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0009408"(response to heat)|go:"GO:0009651"(response to salt stress)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043621"(protein self-association)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0140311"(protein sequestering activity)|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR031107|sgd:YDR171W(identity)	ensembl:ENSG00000158301(gene)|ensembl:ENST00000332262(transcript)|ensembl:ENST00000483720(transcript)|ensembl:ENST00000486814(transcript)|ensembl:ENST00000535209(transcript)|ensembl:ENST00000543253(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0061484"(hematopoietic stem cell homeostasis)|interpro:IPR006911(Protein of unknown function DUF634)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR043374|refseq:NP_001004051.1|refseq:NP_001171803.1|refseq:NP_001171804.1|refseq:NP_001171805.1|refseq:NP_001186747.1|refseq:NP_612446.1|entrezgene/locuslink:114928(identity)	-	crc64:DF353A76493E3CE6	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:izvrv04fA3zcBqTeUeHD/erKGf4559292	rogid:aUbvpCvGto1y4Rqnri7qaKaygQ89606	intact-crc:1379C7F6E7EF22C1|rigid:BCJ58eKd4YPAhwvLi21UIAYmB3k	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12446	uniprotkb:O43639	intact:EBI-10022|uniprotkb:D6W2N7|ensemblfungi:YOR181W	intact:EBI-713635|uniprotkb:Q9BWN9|uniprotkb:Q9UIC3|ensembl:ENSP00000233154|ensembl:ENSP00000377018|uniprotkb:D3DVK1	psi-mi:las17_yeast(display_long)|uniprotkb:LAS17(gene name)|psi-mi:LAS17(display_short)|uniprotkb:YOR181W(locus name)	psi-mi:nck2_human(display_long)|uniprotkb:NCK adaptor protein 2(gene name synonym)|uniprotkb:SH2/SH3 adaptor protein NCK-beta(gene name synonym)|uniprotkb:NCK2(gene name)|psi-mi:NCK2(display_short)|uniprotkb:GRB4(gene name synonym)|uniprotkb:Growth factor receptor-bound protein 4(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11537423|imex:IM-24995-1580	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014824.1|sgd:S000005707|ensemblfungi:YOR181W(gene)|ensemblfungi:YOR181W_mRNA(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007015"(actin filament organization)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030479"(actin cortical patch)|go:"GO:0032233"(positive regulation of actin filament bundle assembly)|go:"GO:0043332"(mating projection tip)|go:"GO:0045010"(actin nucleation)|go:"GO:0051666"(actin cortical patch localization)|go:"GO:0071933"(Arp2/3 complex binding)|go:"GO:0140224"(SLAC complex)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR000697(EVH1)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR027641|interpro:IPR033927|rcsb pdb:1ZUK|dip:DIP-963N|mint:Q12446|sgd:YOR181W(identity)	refseq:XP_006712860.1|refseq:NP_001004720.1|refseq:NP_003572.2|ensembl:ENSG00000071051(gene)|ensembl:ENST00000233154(transcript)|ensembl:ENST00000393349(transcript)|go:"GO:0001771"(immunological synapse formation)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0007015"(actin filament organization)|go:"GO:0007165"(signal transduction)|go:"GO:0007172"(signal complex assembly)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007176"(regulation of epidermal growth factor-activated receptor activity)|go:"GO:0008093"(cytoskeletal anchor activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0012506"(vesicle membrane)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016477"(cell migration)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0036493"(positive regulation of translation in response to endoplasmic reticulum stress)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042110"(T cell activation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0060996"(dendritic spine development)|go:"GO:0097110"(scaffold protein binding)|go:"GO:1902237"(positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903898"(negative regulation of PERK-mediated unfolded protein response)|go:"GO:1903912"(negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation)|go:"GO:1990441"(negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR017304(Cytoplasmic, NCK)|interpro:IPR028524|interpro:IPR035559|interpro:IPR035560|interpro:IPR035561|interpro:IPR035883|interpro:IPR036028|interpro:IPR036860|mint:O43639|rcsb pdb:1U5S|rcsb pdb:1WX6|rcsb pdb:1Z3K|rcsb pdb:2B86|rcsb pdb:2CIA|rcsb pdb:2FRW|rcsb pdb:2FRY|rcsb pdb:2JXB|rcsb pdb:4E6R|reactome:R-HSA-186763|reactome:R-HSA-373753|reactome:R-HSA-3928664|reactome:R-HSA-428540|reactome:R-HSA-4420097|reactome:R-HSA-8985801|reactome:R-HSA-9013420|reactome:R-HSA-9013424|refseq:XP_016860592.1|refseq:XP_016860593.1|refseq:XP_016860594.1|refseq:XP_011510293.1|entrezgene/locuslink:8440(identity)	-	crc64:4488355563AA2645	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:TfQ256gBQPp1T8Ntu2AvktFnypA559292	rogid:WV9nJ78Im/ga5KQlRuSN2ODzWpQ9606	intact-crc:7E622C4DB19F0658|rigid:RsfL2QngUqX+Q1QuSE7cTsedaZ8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12446	uniprotkb:O43586	intact:EBI-10022|uniprotkb:D6W2N7|ensemblfungi:YOR181W	intact:EBI-1050964|uniprotkb:O43585|uniprotkb:O95657|uniprotkb:B5BUK4|uniprotkb:B5BU74|ensembl:ENSP00000452746	psi-mi:las17_yeast(display_long)|uniprotkb:LAS17(gene name)|psi-mi:LAS17(display_short)|uniprotkb:YOR181W(locus name)	psi-mi:ppip1_human(display_long)|uniprotkb:CD2-binding protein 1(gene name synonym)|uniprotkb:H-PIP(gene name synonym)|uniprotkb:PSTPIP1(gene name)|psi-mi:PSTPIP1(display_short)|uniprotkb:CD2BP1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11537414|imex:IM-24995-1579	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014824.1|sgd:S000005707|ensemblfungi:YOR181W(gene)|ensemblfungi:YOR181W_mRNA(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007015"(actin filament organization)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030479"(actin cortical patch)|go:"GO:0032233"(positive regulation of actin filament bundle assembly)|go:"GO:0043332"(mating projection tip)|go:"GO:0045010"(actin nucleation)|go:"GO:0051666"(actin cortical patch localization)|go:"GO:0071933"(Arp2/3 complex binding)|go:"GO:0140224"(SLAC complex)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR000697(EVH1)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR027641|interpro:IPR033927|rcsb pdb:1ZUK|dip:DIP-963N|mint:Q12446|sgd:YOR181W(identity)	refseq:NP_003969.2|refseq:NP_001308064.1|refseq:NP_001308066.1|ensembl:ENSG00000140368(gene)|ensembl:ENST00000558012(transcript)|go:"GO:0001931"(uropod)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0006954"(inflammatory response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0032154"(cleavage furrow)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051015"(actin filament binding)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR027267|interpro:IPR030777|interpro:IPR031160|interpro:IPR036028|mint:O43586|rcsb pdb:2DIL|reactome:R-HSA-844456|reactome:R-HSA-9660826|entrezgene/locuslink:9051(identity)	-	crc64:4488355563AA2645	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:TfQ256gBQPp1T8Ntu2AvktFnypA559292	rogid:JWK4dCYdcVF6mKwe+hoOri1wwps9606	intact-crc:438FFEDA627C001B|rigid:xMK64f8TXbrA2jdbHT/A3Faf260	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12439	uniprotkb:P63279	intact:EBI-2342872|uniprotkb:D6W2Q1	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	psi-mi:yo21a_yeast(display_long)|uniprotkb:TY2A-OR1(gene name)|psi-mi:TY2A-OR1(display_short)|uniprotkb:YORCTy2-1 GAG(gene name synonym)|uniprotkb:O4787(orf name)|uniprotkb:YOR192C-A(locus name)	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11537405|imex:IM-24995-1578	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000007353|interpro:IPR015820(Retrotransposon Ty1 A, N-terminal)|refseq:NP_058186.1|go:"GO:0000943"(retrotransposon nucleocapsid)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0032197"(transposition, RNA-mediated)|sgd:YOR192C-A(identity)	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N|entrezgene/locuslink:7329(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:IbfwV+zl9+6yPnQgzLPL0tLgx5s559292	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	intact-crc:48366E9EFF029155|rigid:mwSLHioTwi1SSdJjPRevAC+8v9o	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O75928-2	uniprotkb:Q12439	intact:EBI-348567|ensembl:ENSP00000317163|intact:EBI-7259183|intact:MINT-1455402	intact:EBI-2342872|uniprotkb:D6W2Q1	psi-mi:o75928-2(display_long)|uniprotkb:Msx-interacting zinc finger protein(gene name synonym)|uniprotkb:PIAS-NY protein(gene name synonym)|uniprotkb:Protein inhibitor of activated STAT x(gene name synonym)|uniprotkb:Protein inhibitor of activated STAT2(gene name synonym)|uniprotkb:PIAS2(gene name)|psi-mi:PIAS2(display_short)|uniprotkb:PIASX(gene name synonym)|uniprotkb:Androgen receptor-interacting protein 3(gene name synonym)|uniprotkb:DAB2-interacting protein(gene name synonym)|uniprotkb:PIASx-alpha(isoform synonym)|uniprotkb:ARIP3(isoform synonym)|uniprotkb:E3 SUMO-protein transferase PIAS2(gene name synonym)	psi-mi:yo21a_yeast(display_long)|uniprotkb:TY2A-OR1(gene name)|psi-mi:TY2A-OR1(display_short)|uniprotkb:YORCTy2-1 GAG(gene name synonym)|uniprotkb:O4787(orf name)|uniprotkb:YOR192C-A(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11537396|imex:IM-24995-1577	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-348555(pias2_human)|ensembl:ENSG00000078043(gene)|ensembl:ENST00000324794(transcript)|uniprotkb:O75928-2(isoform-parent)|entrezgene/locuslink:9063(identity)	sgd:S000007353|interpro:IPR015820(Retrotransposon Ty1 A, N-terminal)|refseq:NP_058186.1|go:"GO:0000943"(retrotransposon nucleocapsid)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0032197"(transposition, RNA-mediated)|sgd:YOR192C-A(identity)	-	isoform-comment:"Contains a glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) at position 562."	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:JNC3UGf8YuVcrXbFnO27d4orf4I9606	rogid:IbfwV+zl9+6yPnQgzLPL0tLgx5s559292	intact-crc:897A76A5337D954F|rigid:7gCJHwxB2mFvsGjlOGmatiloMro	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O14641	uniprotkb:Q12439	intact:EBI-740850|ensembl:ENSP00000005340|uniprotkb:Q53XM0|uniprotkb:D3DTN3	intact:EBI-2342872|uniprotkb:D6W2Q1	psi-mi:dvl2_human(display_long)|uniprotkb:DSH homolog 2(gene name synonym)|uniprotkb:DVL2(gene name)|psi-mi:DVL2(display_short)	psi-mi:yo21a_yeast(display_long)|uniprotkb:TY2A-OR1(gene name)|psi-mi:TY2A-OR1(display_short)|uniprotkb:YORCTy2-1 GAG(gene name synonym)|uniprotkb:O4787(orf name)|uniprotkb:YOR192C-A(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11537387|imex:IM-24995-1576	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004413.1|ensembl:ENSG00000004975(gene)|ensembl:ENST00000005340(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005109"(frizzled binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0007507"(heart development)|go:"GO:0016235"(aggresome)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044340"(canonical Wnt signaling pathway involved in regulation of cell proliferation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0150012"(positive regulation of neuron projection arborization)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008341(Dishevelled-2 region)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:O14641|rcsb pdb:2REY|rcsb pdb:3CBX|rcsb pdb:3CBY|rcsb pdb:3CBZ|rcsb pdb:3CC0|rcsb pdb:4WIP|rcsb pdb:5LNP|rcsb pdb:5SUY|rcsb pdb:5SUZ|rcsb pdb:6IW3|rcsb pdb:6JCK|reactome:R-HSA-201681|reactome:R-HSA-201688|reactome:R-HSA-2028269|reactome:R-HSA-4086400|reactome:R-HSA-4608870|reactome:R-HSA-4641258|reactome:R-HSA-4641262|reactome:R-HSA-5099900|reactome:R-HSA-5368598|reactome:R-HSA-5663220|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9673324|ensembl:ENSP00000005340|dip:DIP-34433N|entrezgene/locuslink:1856(identity)	sgd:S000007353|interpro:IPR015820(Retrotransposon Ty1 A, N-terminal)|refseq:NP_058186.1|go:"GO:0000943"(retrotransposon nucleocapsid)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0032197"(transposition, RNA-mediated)|sgd:YOR192C-A(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:2Vdc8oRnT4Mz/j+EXQXrL3AszOc9606	rogid:IbfwV+zl9+6yPnQgzLPL0tLgx5s559292	intact-crc:F3F4C3E5CDBF3118|rigid:yfRPz+N95NdSBBchwTwQi26ibj4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12431	uniprotkb:Q8N6L0	intact:EBI-2345238|uniprotkb:D6VXY8|ensemblfungi:YLL014W	intact:EBI-749265|uniprotkb:Q96MC3|ensembl:ENSP00000404220	psi-mi:emc6_yeast(display_long)|uniprotkb:L1321(orf name)|uniprotkb:YLL014W(locus name)|uniprotkb:EMC6(gene name)|psi-mi:EMC6(display_short)	psi-mi:kash5_human(display_long)|uniprotkb:KASH5(gene name)|psi-mi:KASH5(display_short)|uniprotkb:CCDC155(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 155(gene name synonym)|uniprotkb:KASH domain-containing protein 5(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11537378|imex:IM-24995-1575	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003937|refseq:NP_013087.1|dip:DIP-988N|ensemblfungi:YLL014W(gene)|ensemblfungi:YLL014W_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0072546"(EMC complex)|interpro:IPR029008|rcsb pdb:6WB9|rcsb pdb:7KRA|rcsb pdb:7KTX|sgd:YLL014W(identity)	refseq:NP_653289.3|ensembl:ENSG00000161609(gene)|ensembl:ENST00000447857(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034397"(telomere localization)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051225"(spindle assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0090172"(microtubule cytoskeleton organization involved in homologous chromosome segregation)|go:"GO:0090220"(chromosome localization to nuclear envelope involved in homologous chromosome segregation)|go:"GO:0090619"(meiotic spindle pole)|interpro:IPR011992(EF-Hand type)|interpro:IPR028168|interpro:IPR028170|interpro:IPR039508|mint:Q8N6L0|rcsb pdb:6R2I|rcsb pdb:6WMF|entrezgene/locuslink:147872(identity)	-	crc64:36C316F18156823E	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:eDM+DjV86zLNJ9eE07m60y7HWSI559292	rogid:Wl9L7AcvDHCZuKjYLn8QgGIbZTc9606	intact-crc:55E3F64F09EEFEE7|rigid:YiShuBqvKw76aSAZ7VNzTxqvKJI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O94972	uniprotkb:Q12417	intact:EBI-741602|uniprotkb:Q7Z3E6|uniprotkb:Q8IYF7|uniprotkb:Q8WYF7|intact:EBI-28976055|ensembl:ENSP00000262294|ensembl:ENSP00000376785|uniprotkb:A8K0V9|uniprotkb:A8K8U4|uniprotkb:A8MZ79|uniprotkb:B4DGZ3|uniprotkb:F8WEE6	intact:EBI-710|uniprotkb:D6W3L8|ensemblfungi:YPL151C	psi-mi:tri37_human(display_long)|uniprotkb:Mulibrey nanism protein(gene name synonym)|uniprotkb:TRIM37(gene name)|psi-mi:TRIM37(display_short)|uniprotkb:KIAA0898(gene name synonym)|uniprotkb:MUL(gene name synonym)|uniprotkb:POB1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 37(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM37(gene name synonym)	psi-mi:prp46_yeast(display_long)|uniprotkb:CWC1(gene name synonym)|uniprotkb:PRP nineteen-associated complex protein 50(gene name synonym)|uniprotkb:PRP19-associated complex protein 50(gene name synonym)|uniprotkb:P2594(orf name)|uniprotkb:YPL151C(locus name)|uniprotkb:PRP46(gene name)|psi-mi:PRP46(display_short)|uniprotkb:NTC50(gene name synonym)|uniprotkb:Pre-mRNA-processing protein 46(gene name synonym)|uniprotkb:Complexed with CEF1 protein 1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11537369|imex:IM-24995-1574	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001005207.1|refseq:NP_056109.1|refseq:NP_001307916.1|ensembl:ENSP00000262294|ensembl:ENST00000393065|ensembl:ENSP00000376784|ensembl:ENSP00000376785|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046600"(negative regulation of centriole replication)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070842"(aggresome assembly)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002083(MATH)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR008974(TRAF-like)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR037299|rcsb pdb:3LRQ|reactome:R-HSA-983168|ensembl:ENSG00000108395(gene)|ensembl:ENST00000262294(transcript)|ensembl:ENST00000393066(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005777"(peroxisome)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016235"(aggresome)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0035518"(histone H2A monoubiquitination)|refseq:NP_001307919.1|dip:DIP-34437N|entrezgene/locuslink:4591(identity)	refseq:NP_015174.1|sgd:S000006072|ensemblfungi:YPL151C(gene)|ensemblfungi:YPL151C_mRNA(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000974"(Prp19 complex)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|dip:DIP-3994N|mint:Q12417|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|sgd:YPL151C(identity)	-	-	crc64:0E888F566A5414BD	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:y2njeO0MUBrKU9MUvkbo1uZmqkE9606	rogid:016ynVER9V3d44NwkqRG7TIvf9w559292	intact-crc:506089ABA20896B1|rigid:KNoTEP3FRmEm2D+VOCvUV7vagdM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q08379	uniprotkb:Q12417	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	intact:EBI-710|uniprotkb:D6W3L8|ensemblfungi:YPL151C	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:prp46_yeast(display_long)|uniprotkb:CWC1(gene name synonym)|uniprotkb:PRP nineteen-associated complex protein 50(gene name synonym)|uniprotkb:PRP19-associated complex protein 50(gene name synonym)|uniprotkb:P2594(orf name)|uniprotkb:YPL151C(locus name)|uniprotkb:PRP46(gene name)|psi-mi:PRP46(display_short)|uniprotkb:NTC50(gene name synonym)|uniprotkb:Pre-mRNA-processing protein 46(gene name synonym)|uniprotkb:Complexed with CEF1 protein 1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11537358|imex:IM-24995-1573	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N|entrezgene/locuslink:2801(identity)	refseq:NP_015174.1|sgd:S000006072|ensemblfungi:YPL151C(gene)|ensemblfungi:YPL151C_mRNA(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000974"(Prp19 complex)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|dip:DIP-3994N|mint:Q12417|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|sgd:YPL151C(identity)	-	-	crc64:0E888F566A5414BD	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2017/05/26	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	rogid:016ynVER9V3d44NwkqRG7TIvf9w559292	intact-crc:375A5AAAE63889C6|rigid:gKJm6NwORNiNROLKTG4Oi1gRKiY	false	sufficient binding region:383-1002	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12389	uniprotkb:O14641	intact:EBI-5644|uniprotkb:D6VRW1|ensemblfungi:YDL031W	intact:EBI-740850|ensembl:ENSP00000005340|uniprotkb:Q53XM0|uniprotkb:D3DTN3	psi-mi:dbp10_yeast(display_long)|uniprotkb:DBP10(gene name)|psi-mi:DBP10(display_short)|uniprotkb:YDL031W(locus name)|uniprotkb:D2770(orf name)|uniprotkb:DEAD box protein 10(gene name synonym)	psi-mi:dvl2_human(display_long)|uniprotkb:DSH homolog 2(gene name synonym)|uniprotkb:DVL2(gene name)|psi-mi:DVL2(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11537349|imex:IM-24995-1572	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010253.2|sgd:S000002189|dip:DIP-6387N|mint:Q12389|ensemblfungi:YDL031W(gene)|ensemblfungi:YDL031W_mRNA(transcript)|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000466"("maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0042802"(identical protein binding)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902626"(assembly of large subunit precursor of preribosome)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR012541(DBP10CT)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|interpro:IPR033517|sgd:YDL031W(identity)	refseq:NP_004413.1|ensembl:ENSG00000004975(gene)|ensembl:ENST00000005340(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005109"(frizzled binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0007507"(heart development)|go:"GO:0016235"(aggresome)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044340"(canonical Wnt signaling pathway involved in regulation of cell proliferation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0150012"(positive regulation of neuron projection arborization)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008341(Dishevelled-2 region)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:O14641|rcsb pdb:2REY|rcsb pdb:3CBX|rcsb pdb:3CBY|rcsb pdb:3CBZ|rcsb pdb:3CC0|rcsb pdb:4WIP|rcsb pdb:5LNP|rcsb pdb:5SUY|rcsb pdb:5SUZ|rcsb pdb:6IW3|rcsb pdb:6JCK|reactome:R-HSA-201681|reactome:R-HSA-201688|reactome:R-HSA-2028269|reactome:R-HSA-4086400|reactome:R-HSA-4608870|reactome:R-HSA-4641258|reactome:R-HSA-4641262|reactome:R-HSA-5099900|reactome:R-HSA-5368598|reactome:R-HSA-5663220|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9673324|ensembl:ENSP00000005340|dip:DIP-34433N|entrezgene/locuslink:1856(identity)	-	crc64:0533013C276095DF	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:PHnLvx2Kk2uAkF21YkvqyoJqTWg559292	rogid:2Vdc8oRnT4Mz/j+EXQXrL3AszOc9606	intact-crc:9FBCBA8A205760D8|rigid:hCU0PErWfmZc22HNiL+Lm8Gk1Zk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12527	uniprotkb:O43597	intact:EBI-31977|uniprotkb:D6W457|ensemblfungi:YPR049C	intact:EBI-742487|uniprotkb:Q5T6Z7|ensembl:ENSP00000366306|ensembl:ENSP00000366308|uniprotkb:B2R9J9	psi-mi:atg11_yeast(display_long)|uniprotkb:Cytoplasm to vacuole targeting protein 9(gene name synonym)|uniprotkb:ATG11(gene name)|psi-mi:ATG11(display_short)|uniprotkb:CVT9(gene name synonym)|uniprotkb:YPR049C(locus name)|uniprotkb:YP9499.07c(orf name)	psi-mi:spy2_human(display_long)|uniprotkb:SPRY2(gene name)|psi-mi:SPRY2(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11537513|imex:IM-24995-1590	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015374.1|sgd:S000006253|dip:DIP-1492N|mint:Q12527|ensemblfungi:YPR049C(gene)|ensemblfungi:YPR049C_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000149"(SNARE binding)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0006914"(autophagy)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0034629"|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061709"(reticulophagy)|go:"GO:0140255"(regulation of cellular response to phosphate starvation)|go:"GO:1990316"(Atg1/ULK1 kinase complex)|go:"GO:2000786"(positive regulation of autophagosome assembly)|interpro:IPR019460|interpro:IPR040040|rcsb pdb:6VZF|reactome:R-SCE-1632852|sgd:YPR049C(identity)	refseq:NP_005833.1|rcsb pdb:5HL0|reactome:R-HSA-1295596|reactome:R-HSA-182971|rcsb pdb:5HKZ|ensembl:ENST00000377102(transcript)|ensembl:ENST00000377104(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|ensembl:ENSG00000136158(gene)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030291"(protein serine/threonine kinase inhibitor activity)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031345"(negative regulation of cell projection organization)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0032587"(ruffle membrane)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0045165"(cell fate commitment)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048513"(animal organ development)|go:"GO:0051387"(negative regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060437"(lung growth)|go:"GO:0060449"(bud elongation involved in lung branching)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:1900747"(negative regulation of vascular endothelial growth factor signaling pathway)|go:"GO:1902747"(negative regulation of lens fiber cell differentiation)|go:"GO:1990752"(microtubule end)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR007875(Sprouty)|interpro:IPR030780|mint:O43597|rcsb pdb:3BUM|rcsb pdb:3OB1|rcsb pdb:5HKY|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|refseq:NP_001305465.1|refseq:NP_001305466.1|refseq:NP_001305467.1|entrezgene/locuslink:10253(identity)	-	crc64:A904B92E9AE79449	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:26PElwvrl3YKwoQU7YdkmR0ln3o559292	rogid:u1omauzisc6MdZlogMotUmtauSI9606	intact-crc:4F8F54045F9DB94F|rigid:a/f0lR/A9heQ5jUrRycNpH6q0PA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12511	uniprotkb:Q8N9N5-2	intact:EBI-36488|uniprotkb:D6W2F1|ensemblfungi:YOR090C	intact:EBI-11524452|ensembl:ENSP00000347125	psi-mi:pdp1_yeast(display_long)|uniprotkb:PTC5(gene name)|psi-mi:PTC5(display_short)|uniprotkb:Phosphatase two C protein 5(gene name synonym)|uniprotkb:PPP1(gene name synonym)|uniprotkb:Protein phosphatase 2C homolog 5(gene name synonym)|uniprotkb:Protein phosphatase of PDH protein 1(gene name synonym)|uniprotkb:Pyruvate dehydrogenase complex phosphatase 1(gene name synonym)|uniprotkb:YOR3157C(orf name)|uniprotkb:YOR090C(locus name)	psi-mi:q8n9n5-2(display_long)|uniprotkb:BANP(gene name)|psi-mi:BANP(display_short)|uniprotkb:BEN domain-containing protein 1(gene name synonym)|uniprotkb:BEND1(gene name synonym)|uniprotkb:Btg3-associated nuclear protein(gene name synonym)|uniprotkb:SMAR1(gene name synonym)|uniprotkb:Scaffold/matrix-associated region-1-binding protein(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11537504|imex:IM-24995-1589	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014733.1|sgd:S000005616|mint:Q12511|dip:DIP-6439N|ensemblfungi:YOR090C(gene)|ensemblfungi:YOR090C_mRNA(transcript)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0004741"("[pyruvate dehydrogenase (lipoamide)] phosphatase activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:1904184"(positive regulation of pyruvate dehydrogenase activity)|interpro:IPR000222(Protein phosphatase 2C,  manganese/magnesium aspartate binding site)|interpro:IPR001932(Protein phosphatase 2C-related)|interpro:IPR015655(Protein phosphatase 2C)|interpro:IPR036457|sgd:YOR090C(identity)	ensembl:ENSG00000172530(gene)|ensembl:ENST00000355022(transcript)|intact:EBI-744695(isoform-parent)|uniprotkb:Q8N9N5-2(isoform-parent)|entrezgene/locuslink:54971(identity)	-	crc64:07A5AF33FA72CC2A	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:AepMamITZgBeuBC3Gni6DMkg35E559292	rogid:ESe6iCAhvq+i57fQHz3rGyg6UOo9606	intact-crc:980FDBAA0366FE80|rigid:LbM1zrUYsHvGH+eLkyJtoDtaJ8E	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q93062-3	uniprotkb:Q12484	intact:EBI-740343|ensembl:ENSP00000340176	intact:EBI-29987|uniprotkb:A0A1S0T0C0|ensemblfungi:YOR343C	psi-mi:q93062-3(display_long)|uniprotkb:RBPMS(gene name)|psi-mi:RBPMS(display_short)|uniprotkb:HERMES(gene name synonym)|uniprotkb:Heart and RRM expressed sequence(gene name synonym)	psi-mi:yo343_yeast(display_long)|uniprotkb:O6287(orf name)|uniprotkb:YOR343C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11537495|imex:IM-24995-1588	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-740322(rbpms_human)|uniprotkb:Q93062-3(isoform-parent)|ensembl:ENSG00000157110(gene)|ensembl:ENST00000339877(transcript)|entrezgene/locuslink:11030(identity)	sgd:S000005870|ensemblfungi:YOR343C(gene)|ensemblfungi:YOR343C_mRNA(transcript)|sgd:YOR343C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:nlPMQAJoKEbPYBwsL3xodmCKd7c9606	rogid:ULgWWTa6oS2393jSgXiCDeyIVlo559292	intact-crc:DD48A33DFB482FC3|rigid:dP4sHialG+KA7qhUhJS0Z/89y2s	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12481	uniprotkb:O14641	intact:EBI-31770|uniprotkb:D6W2Y5|ensemblfungi:YOR287C	intact:EBI-740850|ensembl:ENSP00000005340|uniprotkb:Q53XM0|uniprotkb:D3DTN3	psi-mi:rrp36_yeast(display_long)|uniprotkb:RRP36(gene name)|psi-mi:RRP36(display_short)|uniprotkb:Ribosomal RNA-processing protein 36(gene name synonym)|uniprotkb:YOR287C(locus name)	psi-mi:dvl2_human(display_long)|uniprotkb:DSH homolog 2(gene name synonym)|uniprotkb:DVL2(gene name)|psi-mi:DVL2(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11537486|imex:IM-24995-1587	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014930.1|sgd:S000005813|interpro:IPR009292(Protein of unknown function DUF947)|mint:Q12481|ensemblfungi:YOR287C(gene)|ensemblfungi:YOR287C_mRNA(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000469"(cleavage involved in rRNA processing)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0030686"(90S preribosome)|go:"GO:0042274"(ribosomal small subunit biogenesis)|reactome:R-SCE-6791226|sgd:YOR287C(identity)	refseq:NP_004413.1|ensembl:ENSG00000004975(gene)|ensembl:ENST00000005340(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005109"(frizzled binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0007507"(heart development)|go:"GO:0016235"(aggresome)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044340"(canonical Wnt signaling pathway involved in regulation of cell proliferation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0150012"(positive regulation of neuron projection arborization)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008341(Dishevelled-2 region)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:O14641|rcsb pdb:2REY|rcsb pdb:3CBX|rcsb pdb:3CBY|rcsb pdb:3CBZ|rcsb pdb:3CC0|rcsb pdb:4WIP|rcsb pdb:5LNP|rcsb pdb:5SUY|rcsb pdb:5SUZ|rcsb pdb:6IW3|rcsb pdb:6JCK|reactome:R-HSA-201681|reactome:R-HSA-201688|reactome:R-HSA-2028269|reactome:R-HSA-4086400|reactome:R-HSA-4608870|reactome:R-HSA-4641258|reactome:R-HSA-4641262|reactome:R-HSA-5099900|reactome:R-HSA-5368598|reactome:R-HSA-5663220|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9673324|ensembl:ENSP00000005340|dip:DIP-34433N|entrezgene/locuslink:1856(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:q1HXpxSZvQpnhGzVXmnBNEfWTzI559292	rogid:2Vdc8oRnT4Mz/j+EXQXrL3AszOc9606	intact-crc:2963481DDD7E8B45|rigid:urwWPQOYg+0Za6KFpv7PEA0rWqo	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12476	uniprotkb:Q9BRK4	intact:EBI-31475|uniprotkb:D6VRH7|ensemblfungi:YDL175C	intact:EBI-741037|ensembl:ENSP00000359240|ensembl:ENSP00000359243|uniprotkb:Q8N3I0|uniprotkb:Q96J79|uniprotkb:Q96JL2|uniprotkb:B1AL14|uniprotkb:D3DR72	psi-mi:air2_yeast(display_long)|uniprotkb:Arginine methyltransferase-interacting RING finger protein 2(gene name synonym)|uniprotkb:AIR2(gene name)|psi-mi:AIR2(display_short)|uniprotkb:YDL175C(locus name)	psi-mi:lzts2_human(display_long)|uniprotkb:Protein LAPSER1(gene name synonym)|uniprotkb:LZTS2(gene name)|psi-mi:LZTS2(display_short)|uniprotkb:KIAA1813(gene name synonym)|uniprotkb:LAPSER1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11537477|imex:IM-24995-1586	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010106.1|sgd:S000002334|dip:DIP-2543N|mint:Q12476|ensemblfungi:YDL175C(gene)|ensemblfungi:YDL175C_mRNA(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0006400"(tRNA modification)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031499"(TRAMP complex)|go:"GO:0043629"(ncRNA polyadenylation)|go:"GO:0071031"(nuclear mRNA surveillance of mRNA 3'-end processing)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071036"(nuclear polyadenylation-dependent snoRNA catabolic process)|go:"GO:0071037"(nuclear polyadenylation-dependent snRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071039"(nuclear polyadenylation-dependent CUT catabolic process)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR016713("Poly(A) polymerase complex, Air1/2")|interpro:IPR036875|rcsb pdb:2LLI|rcsb pdb:3NYB|rcsb pdb:4U4C|sgd:YDL175C(identity)	refseq:NP_115805.1|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030496"(midbody)|go:"GO:0031982"(vesicle)|go:"GO:0051013"(microtubule severing)|go:"GO:0051168"(nuclear export)|go:"GO:0051255"(spindle midzone assembly)|go:"GO:0060682"(primary ureteric bud growth)|go:"GO:0072197"(ureter morphogenesis)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|interpro:IPR028597|mint:Q9BRK4|ensembl:ENSG00000107816(gene)|ensembl:ENST00000370220(transcript)|ensembl:ENST00000370223(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0008285"(negative regulation of cell population proliferation)|refseq:XP_016872269.1|refseq:NP_001305028.1|refseq:NP_001305029.1|refseq:NP_001305030.1|refseq:XP_005270279.1|entrezgene/locuslink:84445(identity)	-	crc64:5915C97FA39D6AFC	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:bgMS2UPxQlkuE3+ip5+hgnIdNrE559292	rogid:OaMJmnmfm6JniKUJeyg7fS6zRcw9606	intact-crc:813246A46BB77ED3|rigid:csCOY3mXj3Y8GtsSvIi66tvohpw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12476	uniprotkb:O14641	intact:EBI-31475|uniprotkb:D6VRH7|ensemblfungi:YDL175C	intact:EBI-740850|ensembl:ENSP00000005340|uniprotkb:Q53XM0|uniprotkb:D3DTN3	psi-mi:air2_yeast(display_long)|uniprotkb:Arginine methyltransferase-interacting RING finger protein 2(gene name synonym)|uniprotkb:AIR2(gene name)|psi-mi:AIR2(display_short)|uniprotkb:YDL175C(locus name)	psi-mi:dvl2_human(display_long)|uniprotkb:DSH homolog 2(gene name synonym)|uniprotkb:DVL2(gene name)|psi-mi:DVL2(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11537468|imex:IM-24995-1585	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010106.1|sgd:S000002334|dip:DIP-2543N|mint:Q12476|ensemblfungi:YDL175C(gene)|ensemblfungi:YDL175C_mRNA(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0006400"(tRNA modification)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031499"(TRAMP complex)|go:"GO:0043629"(ncRNA polyadenylation)|go:"GO:0071031"(nuclear mRNA surveillance of mRNA 3'-end processing)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071036"(nuclear polyadenylation-dependent snoRNA catabolic process)|go:"GO:0071037"(nuclear polyadenylation-dependent snRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071039"(nuclear polyadenylation-dependent CUT catabolic process)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR016713("Poly(A) polymerase complex, Air1/2")|interpro:IPR036875|rcsb pdb:2LLI|rcsb pdb:3NYB|rcsb pdb:4U4C|sgd:YDL175C(identity)	refseq:NP_004413.1|ensembl:ENSG00000004975(gene)|ensembl:ENST00000005340(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005109"(frizzled binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0007507"(heart development)|go:"GO:0016235"(aggresome)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044340"(canonical Wnt signaling pathway involved in regulation of cell proliferation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0150012"(positive regulation of neuron projection arborization)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008341(Dishevelled-2 region)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:O14641|rcsb pdb:2REY|rcsb pdb:3CBX|rcsb pdb:3CBY|rcsb pdb:3CBZ|rcsb pdb:3CC0|rcsb pdb:4WIP|rcsb pdb:5LNP|rcsb pdb:5SUY|rcsb pdb:5SUZ|rcsb pdb:6IW3|rcsb pdb:6JCK|reactome:R-HSA-201681|reactome:R-HSA-201688|reactome:R-HSA-2028269|reactome:R-HSA-4086400|reactome:R-HSA-4608870|reactome:R-HSA-4641258|reactome:R-HSA-4641262|reactome:R-HSA-5099900|reactome:R-HSA-5368598|reactome:R-HSA-5663220|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9673324|ensembl:ENSP00000005340|dip:DIP-34433N|entrezgene/locuslink:1856(identity)	-	crc64:5915C97FA39D6AFC	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:bgMS2UPxQlkuE3+ip5+hgnIdNrE559292	rogid:2Vdc8oRnT4Mz/j+EXQXrL3AszOc9606	intact-crc:A30366555097DE53|rigid:+Y9vAv49+0LSxYqVFXNA/5VMQgU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12460	uniprotkb:Q8NHQ1	intact:EBI-17148|ensemblfungi:YLR197W|uniprotkb:D6VYK0	intact:EBI-739624|ensembl:ENSP00000264982|ensembl:ENSP00000419231|uniprotkb:Q96B31|uniprotkb:Q9H2C3|uniprotkb:Q9H2Z1|uniprotkb:Q9H940|uniprotkb:D3DNE9|uniprotkb:B7Z5I8|uniprotkb:B7Z7E8|uniprotkb:F5GZX8	psi-mi:nop56_yeast(display_long)|uniprotkb:SIK1(gene name synonym)|uniprotkb:Ribosome biosynthesis protein SIK1(gene name synonym)|uniprotkb:YLR197W(locus name)|uniprotkb:L8167.9(orf name)|uniprotkb:NOP56(gene name)|psi-mi:NOP56(display_short)|uniprotkb:Suppressor of I kappa b protein 1(gene name synonym)	psi-mi:cep70_human(display_long)|uniprotkb:CEP70(gene name)|psi-mi:CEP70(display_short)|uniprotkb:BITE(gene name synonym)|uniprotkb:p10-binding protein(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11537459|imex:IM-24995-1584	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YLR197W(gene)|ensemblfungi:YLR197W_mRNA(transcript)|go:"GO:0000154"(rRNA modification)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|refseq:NP_013298.1|sgd:S000004187|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0030515"(snoRNA binding)|go:"GO:0030686"(90S preribosome)|go:"GO:0031428"(box C/D RNP complex)|go:"GO:0032040"(small-subunit processome)|interpro:IPR002687(Pre-mRNA processing ribonucleoprotein, binding region)|interpro:IPR012974(NOP5, N-terminal)|interpro:IPR012976(NOSIC)|interpro:IPR036070|interpro:IPR042239|rcsb pdb:5WLC|rcsb pdb:5WYJ|rcsb pdb:5WYK|rcsb pdb:6KE6|rcsb pdb:6LQP|rcsb pdb:6LQQ|rcsb pdb:6LQR|rcsb pdb:6LQS|rcsb pdb:6LQT|rcsb pdb:6LQU|rcsb pdb:6LQV|rcsb pdb:6ND4|rcsb pdb:6ZDT|rcsb pdb:6ZQA|rcsb pdb:6ZQB|rcsb pdb:6ZQC|rcsb pdb:6ZQD|rcsb pdb:6ZQE|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-6791226|dip:DIP-4405N|mint:Q12460|sgd:YLR197W(identity)	ensembl:ENSG00000114107(gene)|ensembl:ENST00000264982(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|interpro:IPR019734|interpro:IPR037692|mint:Q8NHQ1|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|ensembl:ENST00000484888(transcript)|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_077817.2|refseq:XP_016862764.1|refseq:NP_001275893.1|refseq:NP_001275894.1|refseq:NP_001275895.1|refseq:NP_001275896.1|refseq:NP_001307527.1|refseq:NP_001307529.1|entrezgene/locuslink:80321(identity)	-	crc64:F8522A5870EF4842	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:l3UAmoOUECH1uov6nv7MSwSv/3s559292	rogid:S4yveQWcvdVtAUX65gqrJ5Dv0Mc9606	intact-crc:C36763EEF58DC50B|rigid:RlecPvmCstDP0ZnBJvCs/F+2cLA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q16637-3	uniprotkb:Q12460	intact:EBI-395447|ensembl:ENSP00000424926|ensembl:ENSP00000486152|ensembl:ENSP00000487015|ensembl:ENSP00000487029|intact:EBI-8628183|intact:MINT-95595	intact:EBI-17148|ensemblfungi:YLR197W|uniprotkb:D6VYK0	psi-mi:q16637-3(display_long)|uniprotkb:Iso7-SMN(isoform synonym)|uniprotkb:SMN1(gene name)|psi-mi:SMN1(display_short)|uniprotkb:SMN2(gene name)|psi-mi:SMN2(display_short)|uniprotkb:SMN(gene name synonym)|uniprotkb:SMNT(gene name synonym)|uniprotkb:SMNC(gene name synonym)|uniprotkb:Component of gems 1(gene name synonym)|uniprotkb:Gemin-1(gene name synonym)	psi-mi:nop56_yeast(display_long)|uniprotkb:SIK1(gene name synonym)|uniprotkb:Ribosome biosynthesis protein SIK1(gene name synonym)|uniprotkb:YLR197W(locus name)|uniprotkb:L8167.9(orf name)|uniprotkb:NOP56(gene name)|psi-mi:NOP56(display_short)|uniprotkb:Suppressor of I kappa b protein 1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11537450|imex:IM-24995-1583	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-395421(smn_human)|ensembl:ENSG00000275349(gene)|ensembl:ENST00000506163(transcript)|ensembl:ENST00000626847(transcript)|ensembl:ENST00000628353(transcript)|ensembl:ENST00000628642(transcript)|ensembl:ENSG00000172062(gene)|ensembl:ENSG00000205571(gene)|ensembl:ENSG00000273772(gene)|uniprotkb:Q16637-3(isoform-parent)|entrezgene/locuslink:6607(identity)	ensemblfungi:YLR197W(gene)|ensemblfungi:YLR197W_mRNA(transcript)|go:"GO:0000154"(rRNA modification)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|refseq:NP_013298.1|sgd:S000004187|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0030515"(snoRNA binding)|go:"GO:0030686"(90S preribosome)|go:"GO:0031428"(box C/D RNP complex)|go:"GO:0032040"(small-subunit processome)|interpro:IPR002687(Pre-mRNA processing ribonucleoprotein, binding region)|interpro:IPR012974(NOP5, N-terminal)|interpro:IPR012976(NOSIC)|interpro:IPR036070|interpro:IPR042239|rcsb pdb:5WLC|rcsb pdb:5WYJ|rcsb pdb:5WYK|rcsb pdb:6KE6|rcsb pdb:6LQP|rcsb pdb:6LQQ|rcsb pdb:6LQR|rcsb pdb:6LQS|rcsb pdb:6LQT|rcsb pdb:6LQU|rcsb pdb:6LQV|rcsb pdb:6ND4|rcsb pdb:6ZDT|rcsb pdb:6ZQA|rcsb pdb:6ZQB|rcsb pdb:6ZQC|rcsb pdb:6ZQD|rcsb pdb:6ZQE|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-6791226|dip:DIP-4405N|mint:Q12460|sgd:YLR197W(identity)	-	isoform-comment:Thought to be a non-functional protein that lacks the capacity to oligomerize and thus cannot interact with Sm proteins. Primarily derived from SMN2 gene.	crc64:F8522A5870EF4842	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:ICA63eidVxJ219M+YZJ20zNh+xU9606	rogid:l3UAmoOUECH1uov6nv7MSwSv/3s559292	intact-crc:B76A1C2B02F3E3B2|rigid:SFi50B0QqmFhNR2JwpnQnRCGfjs	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12460	uniprotkb:Q16637	intact:EBI-17148|ensemblfungi:YLR197W|uniprotkb:D6VYK0	intact:EBI-395421|uniprotkb:Q13119|uniprotkb:Q549U5|uniprotkb:Q96J51|ensembl:ENSP00000305857|uniprotkb:A8K0V4|ensembl:ENSP00000370083|ensembl:ENSP00000370117|ensembl:ENSP00000370119|ensembl:ENSP00000479920|ensembl:ENSP00000482966|ensembl:ENSP00000483515|ensembl:ENSP00000483819|ensembl:ENSP00000487206|ensembl:ENSP00000487421	psi-mi:nop56_yeast(display_long)|uniprotkb:SIK1(gene name synonym)|uniprotkb:Ribosome biosynthesis protein SIK1(gene name synonym)|uniprotkb:YLR197W(locus name)|uniprotkb:L8167.9(orf name)|uniprotkb:NOP56(gene name)|psi-mi:NOP56(display_short)|uniprotkb:Suppressor of I kappa b protein 1(gene name synonym)	psi-mi:smn_human(display_long)|uniprotkb:SMN1(gene name)|psi-mi:SMN1(display_short)|uniprotkb:SMN(gene name synonym)|uniprotkb:SMNT(gene name synonym)|uniprotkb:SMN2(gene name)|psi-mi:SMN2(display_short)|uniprotkb:SMNC(gene name synonym)|uniprotkb:Component of gems 1(gene name synonym)|uniprotkb:Gemin-1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11537441|imex:IM-24995-1582	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YLR197W(gene)|ensemblfungi:YLR197W_mRNA(transcript)|go:"GO:0000154"(rRNA modification)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|refseq:NP_013298.1|sgd:S000004187|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0030515"(snoRNA binding)|go:"GO:0030686"(90S preribosome)|go:"GO:0031428"(box C/D RNP complex)|go:"GO:0032040"(small-subunit processome)|interpro:IPR002687(Pre-mRNA processing ribonucleoprotein, binding region)|interpro:IPR012974(NOP5, N-terminal)|interpro:IPR012976(NOSIC)|interpro:IPR036070|interpro:IPR042239|rcsb pdb:5WLC|rcsb pdb:5WYJ|rcsb pdb:5WYK|rcsb pdb:6KE6|rcsb pdb:6LQP|rcsb pdb:6LQQ|rcsb pdb:6LQR|rcsb pdb:6LQS|rcsb pdb:6LQT|rcsb pdb:6LQU|rcsb pdb:6LQV|rcsb pdb:6ND4|rcsb pdb:6ZDT|rcsb pdb:6ZQA|rcsb pdb:6ZQB|rcsb pdb:6ZQC|rcsb pdb:6ZQD|rcsb pdb:6ZQE|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-6791226|dip:DIP-4405N|mint:Q12460|sgd:YLR197W(identity)	refseq:NP_000335.1|refseq:NP_059107.1|refseq:NP_075012.1|refseq:NP_075013.1|refseq:NP_075014.1|refseq:NP_075015.1|ensembl:ENSG00000172062(gene)|ensembl:ENSG00000205571(gene)|ensembl:ENSG00000273772(gene)|ensembl:ENSG00000275349(gene)|ensembl:ENSG00000277773(gene)|ensembl:ENST00000351205(transcript)|ensembl:ENST00000380707(transcript)|ensembl:ENST00000380741(transcript)|ensembl:ENST00000380743(transcript)|ensembl:ENST00000614610(transcript)|ensembl:ENST00000618251(transcript)|ensembl:ENST00000618661(transcript)|ensembl:ENST00000622739(transcript)|ensembl:ENST00000627341(transcript)|ensembl:ENST00000629122(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0007399"(nervous system development)|go:"GO:0015030"(Cajal body)|go:"GO:0016604"(nuclear body)|go:"GO:0030018"(Z disc)|go:"GO:0030424"(axon)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043204"(perikaryon)|go:"GO:0097504"(Gemini of coiled bodies)|interpro:IPR002999(Tudor)|interpro:IPR010304(Survival motor neuron)|mint:Q16637|rcsb pdb:1G5V|rcsb pdb:1MHN|rcsb pdb:2LEH|rcsb pdb:4A4E|rcsb pdb:4A4G|rcsb pdb:4GLI|rcsb pdb:4QQ6|rcsb pdb:5XJL|go:"GO:0034719"(SMN-Sm protein complex)|rcsb pdb:5XJQ|rcsb pdb:5XJR|rcsb pdb:5XJS|rcsb pdb:5XJT|rcsb pdb:5XJU|reactome:R-HSA-191859|go:"GO:0032797"(SMN complex)|refseq:NP_001284644.1|ensembl:ENSP00000305857|ensembl:ENSP00000370083|ensembl:ENSP00000370117|ensembl:ENST00000380742|ensembl:ENSP00000370118|ensembl:ENSP00000370119|ensembl:ENST00000503079|ensembl:ENSP00000428128|ensembl:ENST00000506163|ensembl:ENSP00000424926|ensembl:ENST00000611442|ensembl:ENSP00000483768|ensembl:ENST00000614240|ensembl:ENSP00000479279|ensembl:ENSP00000479920|ensembl:ENST00000614773|ensembl:ENSP00000481427|ensembl:ENSP00000483515|ensembl:ENSP00000483819|ensembl:ENST00000622158|ensembl:ENSP00000480906|ensembl:ENSP00000482966|ensembl:ENST00000624634|ensembl:ENSP00000485595|ensembl:ENST00000626847|ensembl:ENSP00000486152|ensembl:ENSP00000487421|ensembl:ENST00000628353|ensembl:ENSP00000487029|ensembl:ENST00000628642|ensembl:ENSP00000487015|ensembl:ENSP00000487206|refseq:XP_016865275.1|dip:DIP-31309N|entrezgene/locuslink:6607(identity)	-	crc64:F8522A5870EF4842	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:l3UAmoOUECH1uov6nv7MSwSv/3s559292	rogid:QGivm7E8suciCWXO4l0zCUzCl2g9606	intact-crc:642E13ABB9F97DB2|rigid:P7RgU+Kz+2UAHNUypIgPhi0aL0o	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9NYB9-2	uniprotkb:Q12446	intact:EBI-11096309|ensembl:ENSP00000261017	intact:EBI-10022|uniprotkb:D6W2N7|ensemblfungi:YOR181W	psi-mi:q9nyb9-2(display_long)|uniprotkb:ABI2(gene name)|psi-mi:ABI2(display_short)|uniprotkb:ARGBPIA(gene name synonym)|uniprotkb:Abelson interactor 2(gene name synonym)|uniprotkb:Abl-binding protein 3(gene name synonym)|uniprotkb:Arg-binding protein 1(gene name synonym)	psi-mi:las17_yeast(display_long)|uniprotkb:LAS17(gene name)|psi-mi:LAS17(display_short)|uniprotkb:YOR181W(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11537432|imex:IM-24995-1581	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-743598(isoform-parent)|ensembl:ENSG00000138443(gene)|ensembl:ENST00000261017(transcript)|uniprotkb:Q9NYB9-2(isoform-parent)|entrezgene/locuslink:10152(identity)	refseq:NP_014824.1|sgd:S000005707|ensemblfungi:YOR181W(gene)|ensemblfungi:YOR181W_mRNA(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007015"(actin filament organization)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030479"(actin cortical patch)|go:"GO:0032233"(positive regulation of actin filament bundle assembly)|go:"GO:0043332"(mating projection tip)|go:"GO:0045010"(actin nucleation)|go:"GO:0051666"(actin cortical patch localization)|go:"GO:0071933"(Arp2/3 complex binding)|go:"GO:0140224"(SLAC complex)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR000697(EVH1)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR027641|interpro:IPR033927|rcsb pdb:1ZUK|dip:DIP-963N|mint:Q12446|sgd:YOR181W(identity)	-	-	crc64:4488355563AA2645	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:VNi9aUeavD8+CCi+n1DXS+7mmbs9606	rogid:TfQ256gBQPp1T8Ntu2AvktFnypA559292	intact-crc:612558EE849C3BF0|rigid:sfFzHpyPEZSJfLqmdNn/LCsybpA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96BA8	uniprotkb:Q12746	intact:EBI-6942903|ensembl:ENSP00000481956|intact:MINT-268046|intact:MINT-8162577|uniprotkb:Q8N2D5|uniprotkb:Q96CP0	intact:EBI-27973|uniprotkb:D6W0G0|ensemblfungi:YML125C	psi-mi:cr3l1_human(display_long)|uniprotkb:CREB3L1(gene name)|psi-mi:CREB3L1(display_short)|uniprotkb:OASIS(gene name synonym)|uniprotkb:PSEC0238(orf name)|uniprotkb:Old astrocyte specifically-induced substance(gene name synonym)	psi-mi:pga3_yeast(display_long)|uniprotkb:YML125C(locus name)|uniprotkb:YM4987.10C(orf name)|uniprotkb:YM7056.01C(orf name)|uniprotkb:PGA3(gene name)|psi-mi:PGA3(display_short)|uniprotkb:NQR1(gene name synonym)|uniprotkb:Processing of GAS1 and ALP protein 3(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11537542|imex:IM-24995-1593	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157613(gene)|ensembl:ENST00000621158(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0070278"(extracellular matrix constituent secretion)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029805|mint:Q96BA8|reactome:R-HSA-8874211|refseq:NP_443086.1|entrezgene/locuslink:90993(identity)	refseq:NP_013581.1|sgd:S000004594|dip:DIP-4519N|ensemblfungi:YML125C(gene)|ensemblfungi:YML125C_mRNA(transcript)|go:"GO:0004128"("cytochrome-b5 reductase activity, acting on NAD(P)H")|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|interpro:IPR001433("Oxidoreductase FAD/NAD(P)-binding")|interpro:IPR001709(Flavoprotein pyridine nucleotide cytochrome reductase)|interpro:IPR001834("NADH:cytochrome b5 reductase (CBR)")|interpro:IPR008333(Oxidoreductase FAD-binding region)|interpro:IPR017927|interpro:IPR017938|interpro:IPR039261|sgd:YML125C(identity)	-	comment:mint|function:"Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE"	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:sMWUFmBeBBCO+T0Y2CuB/un1lBg9606	rogid:+YTQtKGq+TXHYomne3IHzSiugt4559292	intact-crc:213F3F9879A2D97B|rigid:s6UzOJF+NDIejfkL7xf1IporXzc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8N6L0	uniprotkb:Q12746	intact:EBI-749265|uniprotkb:Q96MC3|ensembl:ENSP00000404220	intact:EBI-27973|uniprotkb:D6W0G0|ensemblfungi:YML125C	psi-mi:kash5_human(display_long)|uniprotkb:KASH5(gene name)|psi-mi:KASH5(display_short)|uniprotkb:CCDC155(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 155(gene name synonym)|uniprotkb:KASH domain-containing protein 5(gene name synonym)	psi-mi:pga3_yeast(display_long)|uniprotkb:YML125C(locus name)|uniprotkb:YM4987.10C(orf name)|uniprotkb:YM7056.01C(orf name)|uniprotkb:PGA3(gene name)|psi-mi:PGA3(display_short)|uniprotkb:NQR1(gene name synonym)|uniprotkb:Processing of GAS1 and ALP protein 3(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11537533|imex:IM-24995-1592	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_653289.3|ensembl:ENSG00000161609(gene)|ensembl:ENST00000447857(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034397"(telomere localization)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051225"(spindle assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0090172"(microtubule cytoskeleton organization involved in homologous chromosome segregation)|go:"GO:0090220"(chromosome localization to nuclear envelope involved in homologous chromosome segregation)|go:"GO:0090619"(meiotic spindle pole)|interpro:IPR011992(EF-Hand type)|interpro:IPR028168|interpro:IPR028170|interpro:IPR039508|mint:Q8N6L0|rcsb pdb:6R2I|rcsb pdb:6WMF|entrezgene/locuslink:147872(identity)	refseq:NP_013581.1|sgd:S000004594|dip:DIP-4519N|ensemblfungi:YML125C(gene)|ensemblfungi:YML125C_mRNA(transcript)|go:"GO:0004128"("cytochrome-b5 reductase activity, acting on NAD(P)H")|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|interpro:IPR001433("Oxidoreductase FAD/NAD(P)-binding")|interpro:IPR001709(Flavoprotein pyridine nucleotide cytochrome reductase)|interpro:IPR001834("NADH:cytochrome b5 reductase (CBR)")|interpro:IPR008333(Oxidoreductase FAD-binding region)|interpro:IPR017927|interpro:IPR017938|interpro:IPR039261|sgd:YML125C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Wl9L7AcvDHCZuKjYLn8QgGIbZTc9606	rogid:+YTQtKGq+TXHYomne3IHzSiugt4559292	intact-crc:C691C27ED0B6CCC8|rigid:ATjn9y8MMQnYHvcrAnCXMwya3cI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8IYA8	uniprotkb:Q12527	intact:EBI-8638439|intact:EBI-28969497|ensembl:ENSP00000296449|ensembl:ENSP00000391788|ensembl:ENSP00000407837|uniprotkb:C9JJL0|uniprotkb:Q96LP7|intact:MINT-8162095|uniprotkb:Q05DG9	intact:EBI-31977|uniprotkb:D6W457|ensemblfungi:YPR049C	psi-mi:iho1_human(display_long)|uniprotkb:IHO1(gene name)|psi-mi:IHO1(display_short)|uniprotkb:CCDC36(gene name synonym)|uniprotkb:Cancer/testis antigen 74(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 36(gene name synonym)	psi-mi:atg11_yeast(display_long)|uniprotkb:Cytoplasm to vacuole targeting protein 9(gene name synonym)|uniprotkb:ATG11(gene name)|psi-mi:ATG11(display_short)|uniprotkb:CVT9(gene name synonym)|uniprotkb:YPR049C(locus name)|uniprotkb:YP9499.07c(orf name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11537522|imex:IM-24995-1591	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000296449|ensembl:ENST00000366429|ensembl:ENSP00000403700|ensembl:ENSP00000391788|ensembl:ENSP00000407837|ensembl:ENSG00000173421(gene)|ensembl:ENST00000296449(transcript)|ensembl:ENST00000438782(transcript)|ensembl:ENST00000452691(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0006310"(DNA recombination)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0042138"(meiotic DNA double-strand break formation)|go:"GO:0048477"(oogenesis)|go:"GO:0060629"(regulation of homologous chromosome segregation)|interpro:IPR031529|mint:Q8IYA8|refseq:XP_011531974.1|refseq:XP_011531975.1|refseq:NP_001128669.1|refseq:NP_835467.2|refseq:XP_006713187.1|entrezgene/locuslink:339834(identity)	refseq:NP_015374.1|sgd:S000006253|dip:DIP-1492N|mint:Q12527|ensemblfungi:YPR049C(gene)|ensemblfungi:YPR049C_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000149"(SNARE binding)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0006914"(autophagy)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0034629"|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061709"(reticulophagy)|go:"GO:0140255"(regulation of cellular response to phosphate starvation)|go:"GO:1990316"(Atg1/ULK1 kinase complex)|go:"GO:2000786"(positive regulation of autophagosome assembly)|interpro:IPR019460|interpro:IPR040040|rcsb pdb:6VZF|reactome:R-SCE-1632852|sgd:YPR049C(identity)	-	comment:mint	crc64:A904B92E9AE79449	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:+TNQLExkhmC1NWqsE240Cx7zFVU9606	rogid:26PElwvrl3YKwoQU7YdkmR0ln3o559292	intact-crc:ED76964CD0CB58A7|rigid:yVhxABq4IWXZfrlw9ybCozncEO0	false	sufficient binding region:11-594	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q6Q595	uniprotkb:Q8N6L0	intact:EBI-2346131|uniprotkb:D6VPR2|ensemblfungi:YBL091C-A	intact:EBI-749265|uniprotkb:Q96MC3|ensembl:ENSP00000404220	psi-mi:scs22_yeast(display_long)|uniprotkb:SCS22(gene name)|psi-mi:SCS22(display_short)|uniprotkb:VAP homolog 2(gene name synonym)|uniprotkb:YBL091C-A(locus name)	psi-mi:kash5_human(display_long)|uniprotkb:KASH5(gene name)|psi-mi:KASH5(display_short)|uniprotkb:CCDC155(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 155(gene name synonym)|uniprotkb:KASH domain-containing protein 5(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11537600|imex:IM-24995-1599	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009461.2|sgd:S000007228|interpro:IPR000535(Major sperm protein)|interpro:IPR008962(PapD-like)|interpro:IPR016763(Vesicle-associated membrane protein)|interpro:IPR013783(Immunoglobulin-like fold)|ensemblfungi:YBL091C-A(gene)|ensemblfungi:YBL091C-A_mRNA(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008654"(phospholipid biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033149"(FFAT motif binding)|go:"GO:0060304"(regulation of phosphatidylinositol dephosphorylation)|go:"GO:0061817"(endoplasmic reticulum-plasma membrane tethering)|go:"GO:0090158"(endoplasmic reticulum membrane organization)|sgd:YBL091C-A(identity)	refseq:NP_653289.3|ensembl:ENSG00000161609(gene)|ensembl:ENST00000447857(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034397"(telomere localization)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051225"(spindle assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0090172"(microtubule cytoskeleton organization involved in homologous chromosome segregation)|go:"GO:0090220"(chromosome localization to nuclear envelope involved in homologous chromosome segregation)|go:"GO:0090619"(meiotic spindle pole)|interpro:IPR011992(EF-Hand type)|interpro:IPR028168|interpro:IPR028170|interpro:IPR039508|mint:Q8N6L0|rcsb pdb:6R2I|rcsb pdb:6WMF|entrezgene/locuslink:147872(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:CEe2fGzBKS+GTm7wv+avSs9DXOU559292	rogid:Wl9L7AcvDHCZuKjYLn8QgGIbZTc9606	intact-crc:D93E276DCC214C54|rigid:a3ZZyPKBWZv8lo+SV70dEig6Qc0	false	sufficient binding region:77-175	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9NPI6	uniprotkb:Q3E7X9	intact:EBI-374238|ensembl:ENSP00000476386|uniprotkb:B4DHN9|uniprotkb:U3KQM8	intact:EBI-2343611|uniprotkb:D6W2M5|uniprotkb:P02380|ensemblfungi:YOR167C	psi-mi:dcp1a_human(display_long)|uniprotkb:DCP1A(gene name)|psi-mi:DCP1A(display_short)|uniprotkb:Transcription factor SMIF(gene name synonym)|uniprotkb:Smad4-interacting transcriptional co-activator(gene name synonym)|uniprotkb:SMIF(gene name synonym)	psi-mi:rs28a_yeast(display_long)|uniprotkb:RPS28A(gene name)|psi-mi:RPS28A(display_short)|uniprotkb:RPS33(gene name synonym)|uniprotkb:RPS33A(gene name synonym)|uniprotkb:S33(gene name synonym)|uniprotkb:YS27(gene name synonym)|uniprotkb:O3600(orf name)|uniprotkb:YOR167C(locus name)|uniprotkb:Small ribosomal subunit protein eS28-A(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11537591|imex:IM-24995-1598	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000272886(gene)|ensembl:ENST00000610213(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016020"(membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0019894"(kinesin binding)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|interpro:IPR010334(Dcp1-like decapping)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR031953|mint:Q9NPI6|rcsb pdb:2WX3|rcsb pdb:4B6H|reactome:R-HSA-430039|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-975957|refseq:NP_060873.4|refseq:NP_001277133.1|refseq:NP_001277136.1|refseq:NP_001277134.1|refseq:NP_001277135.1|dip:DIP-31292N|entrezgene/locuslink:55802(identity)	refseq:NP_014810.1|sgd:S000005693|dip:DIP-29384N|ensemblfungi:YOR167C(gene)|ensemblfungi:YOR167C_mRNA(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0006407"(rRNA export from nucleus)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0030490"(maturation of SSU-rRNA)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|interpro:IPR000289(Ribosomal protein S28e)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR028626|rcsb pdb:3J6X|rcsb pdb:3J6Y|rcsb pdb:3J77|rcsb pdb:3J78|rcsb pdb:4U3M|rcsb pdb:4U3N|rcsb pdb:4U3U|rcsb pdb:4U4N|rcsb pdb:4U4O|rcsb pdb:4U4Q|rcsb pdb:4U4R|rcsb pdb:4U4U|rcsb pdb:4U4Y|rcsb pdb:4U4Z|rcsb pdb:4U50|rcsb pdb:4U51|rcsb pdb:4U52|rcsb pdb:4U53|rcsb pdb:4U55|rcsb pdb:4U56|rcsb pdb:4U6F|rcsb pdb:4V6I|rcsb pdb:4V7R|rcsb pdb:4V88|rcsb pdb:4V8Y|rcsb pdb:4V8Z|rcsb pdb:4V92|rcsb pdb:5DAT|rcsb pdb:5DC3|rcsb pdb:5DGE|rcsb pdb:5DGF|rcsb pdb:5DGV|rcsb pdb:5FCI|rcsb pdb:5FCJ|rcsb pdb:5I4L|rcsb pdb:5JPQ|rcsb pdb:5JUO|rcsb pdb:5JUP|rcsb pdb:5JUS|rcsb pdb:5JUT|rcsb pdb:5JUU|rcsb pdb:5LYB|rcsb pdb:5MEI|rcsb pdb:5NDG|rcsb pdb:5NDV|rcsb pdb:5NDW|rcsb pdb:5OBM|rcsb pdb:5ON6|rcsb pdb:5TBW|rcsb pdb:5TGA|rcsb pdb:5TGM|rcsb pdb:5TZS|rcsb pdb:5WLC|rcsb pdb:5WYJ|rcsb pdb:5WYK|rcsb pdb:6FAI|rcsb pdb:6GQ1|rcsb pdb:6GQB|rcsb pdb:6GQV|rcsb pdb:6HHQ|rcsb pdb:6I7O|rcsb pdb:6KE6|rcsb pdb:6LQP|rcsb pdb:6LQQ|rcsb pdb:6LQR|rcsb pdb:6LQS|rcsb pdb:6LQT|rcsb pdb:6LQU|rcsb pdb:6LQV|rcsb pdb:6Q8Y|rcsb pdb:6RBD|rcsb pdb:6RBE|rcsb pdb:6S47|rcsb pdb:6T4Q|rcsb pdb:6TB3|rcsb pdb:6TNU|rcsb pdb:6WDR|rcsb pdb:6WOO|rcsb pdb:6Y7C|rcsb pdb:6Z6J|rcsb pdb:6Z6K|rcsb pdb:6ZQA|rcsb pdb:6ZQB|rcsb pdb:6ZQC|rcsb pdb:6ZQD|rcsb pdb:6ZQE|rcsb pdb:6ZQF|rcsb pdb:6ZQG|rcsb pdb:6ZVI|rcsb pdb:7A1G|rcsb pdb:7AJT|rcsb pdb:7AJU|rcsb pdb:7B7D|rcsb pdb:7NRC|rcsb pdb:7NRD|sgd:YOR167C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2018/09/18	rogid:KIg2pPmAEIiig2SXAJNziN91oCY9606	rogid:gvC4obwu3fwLTPwW+gv2KPlZ02A559292	intact-crc:26423218D054810C|rigid:vROv6ZoiAAm/VhBjEm6qTGKgggk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q3E7B2	uniprotkb:O43765	intact:EBI-3680840|uniprotkb:D6VWB9|ensemblfungi:YJL062W-A	intact:EBI-347996|ensembl:ENSP00000221566|ensembl:ENSP00000503397|ensembl:ENSP00000504495|uniprotkb:Q9BTZ9|intact:EBI-1045243|uniprotkb:Q6FIA9|uniprotkb:D6W610	psi-mi:coa3_yeast(display_long)|uniprotkb:COA3(gene name)|psi-mi:COA3(display_short)|uniprotkb:COX25(gene name synonym)|uniprotkb:RRG10(gene name synonym)|uniprotkb:Required for respiratory growth protein 10(gene name synonym)|uniprotkb:YJL062W-A(locus name)|uniprotkb:Cytochrome c oxidase protein 25(gene name synonym)	psi-mi:sgta_human(display_long)|uniprotkb:SGTA(gene name)|psi-mi:SGTA(display_short)|uniprotkb:SGT(gene name synonym)|uniprotkb:Alpha-SGT(gene name synonym)|uniprotkb:Vpu-binding protein(gene name synonym)|uniprotkb:SGT1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11537582|imex:IM-24995-1597	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	mint:Q3E7B2|sgd:S000007611|refseq:NP_076894.3|ensemblfungi:YJL062W-A(gene)|ensemblfungi:YJL062W-A_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0031305"(integral component of mitochondrial inner membrane)|go:"GO:0033617"(mitochondrial cytochrome c oxidase assembly)|go:"GO:0070130"(negative regulation of mitochondrial translation)|interpro:IPR041752|sgd:YJL062W-A(identity)	rcsb pdb:4CPG|rcsb pdb:4GOD|rcsb pdb:4GOE|rcsb pdb:4GOF|reactome:R-HSA-9609523|rcsb pdb:2VYI|ensembl:ENSG00000104969(gene)|ensembl:ENST00000221566(transcript)|ensembl:ENST00000676943(transcript)|ensembl:ENST00000677149(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072380"(TRC complex)|go:"GO:0098850"(extrinsic component of synaptic vesicle membrane)|go:"GO:1903070"(negative regulation of ER-associated ubiquitin-dependent protein catabolic process)|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)|go:"GO:1903646"(positive regulation of chaperone-mediated protein folding)|go:"GO:1904288"(BAT3 complex binding)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR032374|mint:O43765|refseq:XP_011526480.1|refseq:NP_003012.1|entrezgene/locuslink:6449(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:uBAPwV/LO79+3saLLV4gAWUQPnA559292	rogid:r/Cyj4UJk/cS8QdrbjhTZMPCigI9606	intact-crc:F609D507303DB376|rigid:WHn9ozY9bPYuvwX4RxDe23MdmC4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q3E793	uniprotkb:Q13490	intact:EBI-2344281|uniprotkb:D6VPH1|ensemblfungi:YAL044W-A	intact:EBI-514538|uniprotkb:Q16516|uniprotkb:Q4TTG0|uniprotkb:B4E026|ensembl:ENSP00000227758|ensembl:ENSP00000477613	psi-mi:bol1_yeast(display_long)|uniprotkb:BOL1(gene name)|psi-mi:BOL1(display_short)|uniprotkb:YAL044W-A(locus name)	psi-mi:birc2_human(display_long)|uniprotkb:Inhibitor of apoptosis protein 2(gene name synonym)|uniprotkb:TNFR2-TRAF-signaling complex protein 2(gene name synonym)|uniprotkb:IAP homolog B(gene name synonym)|uniprotkb:RING finger protein 48(gene name synonym)|uniprotkb:BIRC2(gene name)|psi-mi:BIRC2(display_short)|uniprotkb:API1(gene name synonym)|uniprotkb:MIHB(gene name synonym)|uniprotkb:RNF48(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase BIRC2(gene name synonym)|uniprotkb:Cellular inhibitor of apoptosis 1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11537573|imex:IM-24995-1596	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_075206.1|sgd:S000007586|interpro:IPR002634(BolA-like protein)|interpro:IPR036065|ensemblfungi:YAL044W-A(gene)|ensemblfungi:YAL044W-A_mRNA(transcript)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0044572"([4Fe-4S] cluster assembly)|go:"GO:0106035"(protein maturation by [4Fe-4S] cluster transfer)|sgd:YAL044W-A(identity)	refseq:NP_001157.1|refseq:NP_001243095.1|refseq:NP_001243092.1|dip:DIP-33485N|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0045471"(response to ethanol)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051087"(chaperone binding)|go:"GO:0051591"(response to cAMP)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060544"(regulation of necroptotic process)|go:"GO:0060546"(negative regulation of necroptotic process)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070266"(necroptotic process)|go:"GO:0070424"(regulation of nucleotide-binding oligomerization domain containing signaling pathway)|go:"GO:0098770"(FBXO family protein binding)|go:"GO:1901222"(regulation of NIK/NF-kappaB signaling)|go:"GO:1902443"(negative regulation of ripoptosome assembly involved in necroptotic process)|go:"GO:1902523"(positive regulation of protein K63-linked ubiquitination)|go:"GO:1902524"(positive regulation of protein K48-linked ubiquitination)|go:"GO:1902527"(positive regulation of protein monoubiquitination)|go:"GO:2000116"(regulation of cysteine-type endopeptidase activity)|go:"GO:2000377"(regulation of reactive oxygen species metabolic process)|interpro:IPR001315(Caspase Recruitment)|interpro:IPR001370(Proteinase inhibitor I32, inhibitor of apoptosis)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011029(DEATH-like)|interpro:IPR041933|mint:Q13490|rcsb pdb:1QBH|rcsb pdb:2L9M|rcsb pdb:3D9T|rcsb pdb:3D9U|rcsb pdb:3M1D|rcsb pdb:3MUP|rcsb pdb:3OZ1|rcsb pdb:3T6P|rcsb pdb:3UW4|rcsb pdb:4EB9|rcsb pdb:4HY4|rcsb pdb:4HY5|rcsb pdb:4KMN|rcsb pdb:4LGE|rcsb pdb:4LGU|rcsb pdb:4MTI|rcsb pdb:4MU7|rcsb pdb:5M6N|rcsb pdb:6EXW|rcsb pdb:6HPR|rcsb pdb:6W74|rcsb pdb:6W7O|rcsb pdb:6W8I|reactome:R-HSA-111465|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-5213460|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5668541|reactome:R-HSA-5675482|reactome:R-HSA-5676594|reactome:R-HSA-5689880|reactome:R-HSA-937041|ensembl:ENSG00000110330(gene)|ensembl:ENST00000227758(transcript)|ensembl:ENST00000613397(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001741"(XY body)|go:"GO:0001890"(placenta development)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0016740"(transferase activity)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034121"(regulation of toll-like receptor signaling pathway)|go:"GO:0035631"(CD40 receptor complex)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0039535"(regulation of RIG-I signaling pathway)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|entrezgene/locuslink:329(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:9pYGPvGIU56X3neAXP8LQXxWfC4559292	rogid:FOikzyDyDtlv2l69i/WNDNq674A9606	intact-crc:B04601E7F3E013CB|rigid:axSefRuPDtrVgBhaqjmLlfAFKg8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P98170	uniprotkb:Q3E793	intact:EBI-517127|uniprotkb:Q9NQ14|uniprotkb:D3DTF2|ensembl:ENSP00000347858|ensembl:ENSP00000360242|ensembl:ENSP00000395230	intact:EBI-2344281|uniprotkb:D6VPH1|ensemblfungi:YAL044W-A	psi-mi:xiap_human(display_long)|uniprotkb:Inhibitor of apoptosis protein 3(gene name synonym)|uniprotkb:X-linked inhibitor of apoptosis protein(gene name synonym)|uniprotkb:IAP-like protein(gene name synonym)|uniprotkb:XIAP(gene name)|psi-mi:XIAP(display_short)|uniprotkb:API3(gene name synonym)|uniprotkb:IAP3(gene name synonym)|uniprotkb:BIRC4(gene name synonym)|uniprotkb:Baculoviral IAP repeat-containing protein 4(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase XIAP(gene name synonym)	psi-mi:bol1_yeast(display_long)|uniprotkb:BOL1(gene name)|psi-mi:BOL1(display_short)|uniprotkb:YAL044W-A(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11537564|imex:IM-24995-1595	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006724817.1|refseq:NP_001158.2|refseq:NP_001191330.1|refseq:XP_011529631.1|dip:DIP-27626N|ensembl:ENSG00000101966(gene)|ensembl:ENST00000355640(transcript)|ensembl:ENST00000371199(transcript)|ensembl:ENST00000434753(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005876"(spindle microtubule)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030510"(regulation of BMP signaling pathway)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0055070"(copper ion homeostasis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070424"(regulation of nucleotide-binding oligomerization domain containing signaling pathway)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:1902530"(positive regulation of protein linear polyubiquitination)|go:"GO:1990001"(inhibition of cysteine-type endopeptidase activity involved in apoptotic process)|interpro:IPR001370(Proteinase inhibitor I32, inhibitor of apoptosis)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011029(DEATH-like)|interpro:IPR042579|mint:P98170|rcsb pdb:1C9Q|rcsb pdb:1F9X|rcsb pdb:1G3F|rcsb pdb:1G73|rcsb pdb:1I3O|rcsb pdb:1I4O|rcsb pdb:1I51|rcsb pdb:1KMC|rcsb pdb:1NW9|rcsb pdb:1TFQ|rcsb pdb:1TFT|rcsb pdb:2ECG|rcsb pdb:2JK7|rcsb pdb:2KNA|rcsb pdb:2OPY|rcsb pdb:2OPZ|rcsb pdb:2POI|rcsb pdb:2POP|rcsb pdb:2QRA|rcsb pdb:2VSL|rcsb pdb:3CLX|rcsb pdb:3CM2|rcsb pdb:3CM7|rcsb pdb:3EYL|rcsb pdb:3G76|rcsb pdb:3HL5|rcsb pdb:3UW4|rcsb pdb:3UW5|rcsb pdb:4EC4|rcsb pdb:4HY0|rcsb pdb:4IC2|rcsb pdb:4IC3|rcsb pdb:4J3Y|rcsb pdb:4J44|rcsb pdb:4J45|rcsb pdb:4J46|rcsb pdb:4J47|rcsb pdb:4J48|rcsb pdb:4KJU|rcsb pdb:4KJV|rcsb pdb:4KMP|rcsb pdb:4MTZ|rcsb pdb:4OXC|rcsb pdb:4WVS|rcsb pdb:4WVT|rcsb pdb:4WVU|rcsb pdb:5C0K|rcsb pdb:5C0L|rcsb pdb:5C3H|rcsb pdb:5C3K|rcsb pdb:5C7A|rcsb pdb:5C7B|rcsb pdb:5C7C|rcsb pdb:5C7D|rcsb pdb:5C83|rcsb pdb:5C84|rcsb pdb:5M6E|rcsb pdb:5M6F|rcsb pdb:5M6H|rcsb pdb:5M6L|rcsb pdb:5M6M|rcsb pdb:5O6T|rcsb pdb:5OQW|rcsb pdb:6EY2|rcsb pdb:6GJW|rcsb pdb:6QCI|reactome:R-HSA-111459|reactome:R-HSA-111463|reactome:R-HSA-111464|reactome:R-HSA-111469|reactome:R-HSA-3769402|reactome:R-HSA-5213460|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5675482|reactome:R-HSA-8948747|reactome:R-HSA-8948751|reactome:R-HSA-9627069|entrezgene/locuslink:331(identity)	refseq:NP_075206.1|sgd:S000007586|interpro:IPR002634(BolA-like protein)|interpro:IPR036065|ensemblfungi:YAL044W-A(gene)|ensemblfungi:YAL044W-A_mRNA(transcript)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0044572"([4Fe-4S] cluster assembly)|go:"GO:0106035"(protein maturation by [4Fe-4S] cluster transfer)|sgd:YAL044W-A(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:6eDcOay+c2ZmIAD/pwnCDROBwgM9606	rogid:9pYGPvGIU56X3neAXP8LQXxWfC4559292	intact-crc:23F8146E7D8583DD|rigid:53Mz0OG+9oFHUkS4vej15mgo2lo	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q3E793	uniprotkb:O76003	intact:EBI-2344281|uniprotkb:D6VPH1|ensemblfungi:YAL044W-A	intact:EBI-374781|uniprotkb:Q96CE0|uniprotkb:Q9P1B0|uniprotkb:Q9P1B1|uniprotkb:B3KMP7|uniprotkb:B3KMQ5|uniprotkb:Q5JV01|ensembl:ENSP00000330836|ensembl:ENSP00000357633|ensembl:ENSP00000435445|uniprotkb:D3DRG2	psi-mi:bol1_yeast(display_long)|uniprotkb:BOL1(gene name)|psi-mi:BOL1(display_short)|uniprotkb:YAL044W-A(locus name)	psi-mi:glrx3_human(display_long)|uniprotkb:GLRX3(gene name)|psi-mi:GLRX3(display_short)|uniprotkb:Thioredoxin-like protein 2(gene name synonym)|uniprotkb:PKC-interacting cousin of thioredoxin(gene name synonym)|uniprotkb:PKC-theta-interacting protein(gene name synonym)|uniprotkb:PICOT(gene name synonym)|uniprotkb:HUSSY-22(orf name)|uniprotkb:TXNL2(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11537552|imex:IM-24995-1594	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_075206.1|sgd:S000007586|interpro:IPR002634(BolA-like protein)|interpro:IPR036065|ensemblfungi:YAL044W-A(gene)|ensemblfungi:YAL044W-A_mRNA(transcript)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0044572"([4Fe-4S] cluster assembly)|go:"GO:0106035"(protein maturation by [4Fe-4S] cluster transfer)|sgd:YAL044W-A(identity)	ensembl:ENSG00000108010(gene)|ensembl:ENST00000331244(transcript)|ensembl:ENST00000368644(transcript)|ensembl:ENST00000481034(transcript)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0003723"(RNA binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0030018"(Z disc)|go:"GO:0030425"(dendrite)|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051536"(iron-sulfur cluster binding)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|go:"GO:0097573"(glutathione oxidoreductase activity)|interpro:IPR002109(Glutaredoxin)|interpro:IPR004480(Glutaredoxin-related protein)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR033658|interpro:IPR036249|mint:O76003|rcsb pdb:2DIY|rcsb pdb:2WZ9|rcsb pdb:2YAN|rcsb pdb:3ZYW|reactome:R-HSA-917937|refseq:NP_001186797.1|refseq:NP_006532.2|dip:DIP-31306N|entrezgene/locuslink:10539(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:9pYGPvGIU56X3neAXP8LQXxWfC4559292	rogid:iKUSt6zbNzzXSKvW+vXMq3hKsEM9606	intact-crc:BDC02DB1EC5A95EC|rigid:97YEt2Aehe3ybPhcvT6guyxTdD4	false	-	sufficient binding region:147-335	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q15654	uniprotkb:Q8TGM2	intact:EBI-742327|uniprotkb:O15170|uniprotkb:O15275|uniprotkb:Q9BTB2|uniprotkb:Q9BUE5|uniprotkb:Q9BXP3|uniprotkb:Q9UNT4|uniprotkb:A4D2E7|ensembl:ENSP00000200457|uniprotkb:F2ZC07|uniprotkb:F2ZC08	intact:EBI-11537624|ensemblfungi:YLR347W-A	psi-mi:trip6_human(display_long)|uniprotkb:TRIP6(gene name)|psi-mi:TRIP6(display_short)|uniprotkb:OIP1(gene name synonym)|uniprotkb:Opa-interacting protein 1(gene name synonym)|uniprotkb:Zyxin-related protein 1(gene name synonym)	psi-mi:yl347_yeast(display_long)|uniprotkb:YLR347W-A(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11537633|imex:IM-24995-1602	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003293.2|ensembl:ENSP00000200457|ensembl:ENST00000417475|ensembl:ENSP00000413817|ensembl:ENST00000437505|ensembl:ENSP00000410736|ensembl:ENST00000619988|ensembl:ENSP00000479865|ensembl:ENSG00000087077(gene)|ensembl:ENST00000200457(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003723"(RNA binding)|go:"GO:0005149"(interleukin-1 receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0019900"(kinase binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0043009"(chordate embryonic development)|go:"GO:0046872"(metal ion binding)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|interpro:IPR001781(Zinc finger, LIM-type)|mint:Q15654|rcsb pdb:1X61|rcsb pdb:2DLO|dip:DIP-34466N|entrezgene/locuslink:7205(identity)	sgd:S000028681|ensemblfungi:YLR347W-A(gene)|ensemblfungi:YLR347W-A_mRNA(transcript)|sgd:YLR347W-A(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/03/16	rogid:9Okf3b6sMMwX5awAx991GN9iSsQ9606	rogid:eZ3330guTyvylD3kiCyArvlGWGI559292	intact-crc:6485ADD80848C36C|rigid:j9x6kqXpb1RT8oOpj+apAitcB6I	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8TGM2	uniprotkb:Q8N9N5-2	intact:EBI-11537624|ensemblfungi:YLR347W-A	intact:EBI-11524452|ensembl:ENSP00000347125	psi-mi:yl347_yeast(display_long)|uniprotkb:YLR347W-A(locus name)	psi-mi:q8n9n5-2(display_long)|uniprotkb:BANP(gene name)|psi-mi:BANP(display_short)|uniprotkb:BEN domain-containing protein 1(gene name synonym)|uniprotkb:BEND1(gene name synonym)|uniprotkb:Btg3-associated nuclear protein(gene name synonym)|uniprotkb:SMAR1(gene name synonym)|uniprotkb:Scaffold/matrix-associated region-1-binding protein(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11537643|imex:IM-24995-1603	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000028681|ensemblfungi:YLR347W-A(gene)|ensemblfungi:YLR347W-A_mRNA(transcript)|sgd:YLR347W-A(identity)	ensembl:ENSG00000172530(gene)|ensembl:ENST00000355022(transcript)|intact:EBI-744695(isoform-parent)|uniprotkb:Q8N9N5-2(isoform-parent)|entrezgene/locuslink:54971(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/03/16	rogid:eZ3330guTyvylD3kiCyArvlGWGI559292	rogid:ESe6iCAhvq+i57fQHz3rGyg6UOo9606	intact-crc:DB9FE30CDFF60400|rigid:I04O0BHD1/XyGh9QCQ1E7JgUl5o	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12846	uniprotkb:Q8TGQ7	intact:EBI-744942|uniprotkb:Q15525|ensembl:ENSP00000317714|uniprotkb:Q6FHE8|uniprotkb:A8MXY0	intact:EBI-2343396|uniprotkb:D6W4G0|ensemblfungi:YPR159C-A	psi-mi:stx4_human(display_long)|uniprotkb:Renal carcinoma antigen NY-REN-31(gene name synonym)|uniprotkb:STX4(gene name)|psi-mi:STX4(display_short)|uniprotkb:STX4A(gene name synonym)	psi-mi:yp159_yeast(display_long)|uniprotkb:YPR159C-A(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11537652|imex:IM-24995-1604	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000103496(gene)|refseq:NP_004595.2|ensembl:ENST00000313843(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0000322"(storage vacuole)|go:"GO:0002639"(positive regulation of immunoglobulin production)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005768"(endosome)|go:"GO:0005773"(vacuole)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006887"(exocytosis)|go:"GO:0006906"(vesicle fusion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016230"(sphingomyelin phosphodiesterase activator activity)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0032589"(neuron projection membrane)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035493"(SNARE complex assembly)|go:"GO:0035749"(myelin sheath adaxonal region)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0036477"(somatodendritic compartment)|go:"GO:0042581"(specific granule)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043197"(dendritic spine)|go:"GO:0043219"(lateral loop)|go:"GO:0043311"(positive regulation of eosinophil degranulation)|go:"GO:0045202"(synapse)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0048278"(vesicle docking)|go:"GO:0048284"(organelle fusion)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048787"(presynaptic active zone membrane)|go:"GO:0050921"(positive regulation of chemotaxis)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1902041"(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1903575"(cornified envelope assembly)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|reactome:R-HSA-114516|reactome:R-HSA-1236974|reactome:R-HSA-1445148|reactome:R-HSA-199992|reactome:R-HSA-449836|interpro:IPR006011(Syntaxin, N-terminal)|refseq:NP_001259025.1|entrezgene/locuslink:6810(identity)	sgd:S000028725|refseq:NP_878184.1|ensemblfungi:YPR159C-A(gene)|ensemblfungi:YPR159C-A_mRNA(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0016021"(integral component of membrane)|sgd:YPR159C-A(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:NvOLGIGe/XO2aDPSpdPzrtKniZY9606	rogid:QGsci3FKQweBQvaMDdLKyHdq8tM559292	intact-crc:611BEC3C13B83646|rigid:SJ4vQ3B3xUYzq+sCfQ4y92YU6Rk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8TGQ7	uniprotkb:Q8N6L0	intact:EBI-2343396|uniprotkb:D6W4G0|ensemblfungi:YPR159C-A	intact:EBI-749265|uniprotkb:Q96MC3|ensembl:ENSP00000404220	psi-mi:yp159_yeast(display_long)|uniprotkb:YPR159C-A(locus name)	psi-mi:kash5_human(display_long)|uniprotkb:KASH5(gene name)|psi-mi:KASH5(display_short)|uniprotkb:CCDC155(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 155(gene name synonym)|uniprotkb:KASH domain-containing protein 5(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11537661|imex:IM-24995-1605	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000028725|refseq:NP_878184.1|ensemblfungi:YPR159C-A(gene)|ensemblfungi:YPR159C-A_mRNA(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0016021"(integral component of membrane)|sgd:YPR159C-A(identity)	refseq:NP_653289.3|ensembl:ENSG00000161609(gene)|ensembl:ENST00000447857(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034397"(telomere localization)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051225"(spindle assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0090172"(microtubule cytoskeleton organization involved in homologous chromosome segregation)|go:"GO:0090220"(chromosome localization to nuclear envelope involved in homologous chromosome segregation)|go:"GO:0090619"(meiotic spindle pole)|interpro:IPR011992(EF-Hand type)|interpro:IPR028168|interpro:IPR028170|interpro:IPR039508|mint:Q8N6L0|rcsb pdb:6R2I|rcsb pdb:6WMF|entrezgene/locuslink:147872(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:QGsci3FKQweBQvaMDdLKyHdq8tM559292	rogid:Wl9L7AcvDHCZuKjYLn8QgGIbZTc9606	intact-crc:0BDE47AF909A67E8|rigid:H0Zg9HThbB8YZRiGY2k7psd6gUs	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96BA8	uniprotkb:Q8TGQ7	intact:EBI-6942903|ensembl:ENSP00000481956|intact:MINT-268046|intact:MINT-8162577|uniprotkb:Q8N2D5|uniprotkb:Q96CP0	intact:EBI-2343396|uniprotkb:D6W4G0|ensemblfungi:YPR159C-A	psi-mi:cr3l1_human(display_long)|uniprotkb:CREB3L1(gene name)|psi-mi:CREB3L1(display_short)|uniprotkb:OASIS(gene name synonym)|uniprotkb:PSEC0238(orf name)|uniprotkb:Old astrocyte specifically-induced substance(gene name synonym)	psi-mi:yp159_yeast(display_long)|uniprotkb:YPR159C-A(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11537670|imex:IM-24995-1606	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157613(gene)|ensembl:ENST00000621158(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0070278"(extracellular matrix constituent secretion)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029805|mint:Q96BA8|reactome:R-HSA-8874211|refseq:NP_443086.1|entrezgene/locuslink:90993(identity)	sgd:S000028725|refseq:NP_878184.1|ensemblfungi:YPR159C-A(gene)|ensemblfungi:YPR159C-A_mRNA(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0016021"(integral component of membrane)|sgd:YPR159C-A(identity)	-	comment:mint|function:"Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE"	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:sMWUFmBeBBCO+T0Y2CuB/un1lBg9606	rogid:QGsci3FKQweBQvaMDdLKyHdq8tM559292	intact-crc:00D037A0F88512C4|rigid:DeHYvscpGsKzoayjNN8/HmV97AI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8TGM2	intact:EBI-11524292	intact:EBI-11537624|ensemblfungi:YLR347W-A	-	psi-mi:yl347_yeast(display_long)|uniprotkb:YLR347W-A(locus name)	psi-mi:trip6(display_short)|psi-mi:EBI-11524292(display_long)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11537622|imex:IM-24995-1601	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000028681|ensemblfungi:YLR347W-A(gene)|ensemblfungi:YLR347W-A_mRNA(transcript)|sgd:YLR347W-A(identity)	entrezgene/locuslink:7205(identity)	-	-	no-uniprot-update:	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/03/16	rogid:eZ3330guTyvylD3kiCyArvlGWGI559292	rogid:S6W5lkNauGhNejln9bTVoqZjNL49606	intact-crc:7B9085E1E9D823F1|rigid:zt6zAW9KVan93EIdtiZ7tge+kes	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q03393	uniprotkb:Q7LHD1	intact:EBI-712344|ensembl:ENSP00000280362|uniprotkb:Q8WVG8|uniprotkb:B0YJ87	intact:EBI-11537611	psi-mi:ptps_human(display_long)|uniprotkb:PTS(gene name)|psi-mi:PTS(display_short)	psi-mi:ccw22_yeast(display_long)|uniprotkb:CCW22(gene name)|psi-mi:CCW22(display_short)|uniprotkb:YD9302.09C/YD9302.10C(orf name)|uniprotkb:YDR134C(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11537613|imex:IM-24995-1600	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000308.1|ensembl:ENSG00000150787(gene)|ensembl:ENST00000280362(transcript)|go:"GO:0003874"(6-pyruvoyltetrahydropterin synthase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006520"(cellular amino acid metabolic process)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0007417"(central nervous system development)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR007115(6-pyruvoyl tetrahydropterin synthase-related)|interpro:IPR022469|interpro:IPR022470|interpro:IPR038418|rcsb pdb:3I2B|reactome:R-HSA-1474151|entrezgene/locuslink:5805(identity)	interpro:IPR025928|sgd:S000002541|go:"GO:0005576"(extracellular region)|go:"GO:0009277"(fungal-type cell wall)|go:"GO:0031225"(anchored component of membrane)|sgd:YDR134C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/03/16	rogid:Qa3bMpzyvRxrvDq9dZUSQlfbpeg9606	rogid:Jrl6wg+0ObAYQSYzJxhVcNq5QcQ559292	intact-crc:F4AC4919787D9EE2|rigid:1S3ndMY8ZrXubpp6jreEYD5mcK0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8TGQ8	uniprotkb:Q93062-3	intact:EBI-11537679|ensemblfungi:YOL085W-A	intact:EBI-740343|ensembl:ENSP00000340176	psi-mi:yo85a_yeast(display_long)|uniprotkb:YOL085W-A(locus name)	psi-mi:q93062-3(display_long)|uniprotkb:RBPMS(gene name)|psi-mi:RBPMS(display_short)|uniprotkb:HERMES(gene name synonym)|uniprotkb:Heart and RRM expressed sequence(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11537681|imex:IM-24995-1607	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000028708|ensemblfungi:YOL085W-A(gene)|ensemblfungi:YOL085W-A_mRNA(transcript)|sgd:YOL085W-A(identity)	intact:EBI-740322(rbpms_human)|uniprotkb:Q93062-3(isoform-parent)|ensembl:ENSG00000157110(gene)|ensembl:ENST00000339877(transcript)|entrezgene/locuslink:11030(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/03/16	rogid:kZcPWq9185AwxM/LykJ1Bui6Hvs559292	rogid:nlPMQAJoKEbPYBwsL3xodmCKd7c9606	intact-crc:E7FBBD7AFECDEDE8|rigid:l4nCtVQGgG4GhFhdK1AAtRyBsHA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q13557-8	uniprotkb:Q99189	intact:EBI-11534483|ensembl:ENSP00000296402|ensembl:ENSP00000369098	intact:EBI-11597|ensemblfungi:YOR160W|uniprotkb:D6W2L7	psi-mi:q13557-8(display_long)|uniprotkb:CAMKD(gene name synonym)|uniprotkb:CAMK2D(gene name)|psi-mi:CAMK2D(display_short)	psi-mi:mtr10_yeast(display_long)|uniprotkb:YOR160W(locus name)|uniprotkb:MTR10(gene name)|psi-mi:MTR10(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11537690|imex:IM-24995-1608	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-351018(isoform-parent)|ensembl:ENSG00000145349(gene)|ensembl:ENST00000296402(transcript)|ensembl:ENST00000379773(transcript)|uniprotkb:Q13557-8(isoform-parent)|entrezgene/locuslink:817(identity)	go:"GO:0005737"(cytoplasm)|go:"GO:0006403"(RNA localization)|go:"GO:0006404"(RNA import into nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0034399"(nuclear periphery)|go:"GO:0051031"(tRNA transport)|go:"GO:0061015"(snRNA import into nucleus)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013598(Exportin-1/Importin-beta-like)|interpro:IPR016024(Armadillo-type fold)|ensemblfungi:YOR160W(gene)|ensemblfungi:YOR160W_mRNA(transcript)|go:"GO:0005634"(nucleus)|refseq:NP_014803.1|sgd:S000005686|dip:DIP-2358N|sgd:YOR160W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:44T/I8JdalScCNE5Vp/H+PnfdFo9606	rogid:EbfcB0um6KIUegXNsKf6yAD8VRs559292	intact-crc:9B3479A66A92FFB1|rigid:coBbrglAnlIAVfwMr7tOu50OVkI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q99288	uniprotkb:O76003	intact:EBI-30580|uniprotkb:Q05314|uniprotkb:P87337|uniprotkb:Q7LHX4|uniprotkb:D6VS38|ensemblfungi:YDR051C	intact:EBI-374781|uniprotkb:Q96CE0|uniprotkb:Q9P1B0|uniprotkb:Q9P1B1|uniprotkb:B3KMP7|uniprotkb:B3KMQ5|uniprotkb:Q5JV01|ensembl:ENSP00000330836|ensembl:ENSP00000357633|ensembl:ENSP00000435445|uniprotkb:D3DRG2	psi-mi:det1_yeast(display_long)|uniprotkb:DET1(gene name)|psi-mi:DET1(display_short)|uniprotkb:D4202(orf name)|uniprotkb:YDR051C(locus name)|uniprotkb:Decreased ergosterol transport protein 1(gene name synonym)	psi-mi:glrx3_human(display_long)|uniprotkb:GLRX3(gene name)|psi-mi:GLRX3(display_short)|uniprotkb:Thioredoxin-like protein 2(gene name synonym)|uniprotkb:PKC-interacting cousin of thioredoxin(gene name synonym)|uniprotkb:PKC-theta-interacting protein(gene name synonym)|uniprotkb:PICOT(gene name synonym)|uniprotkb:HUSSY-22(orf name)|uniprotkb:TXNL2(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11537699|imex:IM-24995-1609	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002458|refseq:NP_010336.3|dip:DIP-1816N|mint:Q99288|ensemblfungi:YDR051C(gene)|ensemblfungi:YDR051C_mRNA(transcript)|go:"GO:0003993"(acid phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016311"(dephosphorylation)|go:"GO:0016791"(phosphatase activity)|go:"GO:0032366"(intracellular sterol transport)|interpro:IPR001345(Phosphoglycerate/bisphosphoglycerate mutase)|interpro:IPR013078(Phosphoglycerate mutase)|interpro:IPR029033|sgd:YDR051C(identity)	ensembl:ENSG00000108010(gene)|ensembl:ENST00000331244(transcript)|ensembl:ENST00000368644(transcript)|ensembl:ENST00000481034(transcript)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0003723"(RNA binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0030018"(Z disc)|go:"GO:0030425"(dendrite)|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051536"(iron-sulfur cluster binding)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|go:"GO:0097573"(glutathione oxidoreductase activity)|interpro:IPR002109(Glutaredoxin)|interpro:IPR004480(Glutaredoxin-related protein)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR033658|interpro:IPR036249|mint:O76003|rcsb pdb:2DIY|rcsb pdb:2WZ9|rcsb pdb:2YAN|rcsb pdb:3ZYW|reactome:R-HSA-917937|refseq:NP_001186797.1|refseq:NP_006532.2|dip:DIP-31306N|entrezgene/locuslink:10539(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:vwXFLCqrDTeOaIJG7tr6C6a1cFs559292	rogid:iKUSt6zbNzzXSKvW+vXMq3hKsEM9606	intact-crc:FB9903C45181C26C|rigid:a92h/SOoY3koogqVQEMXPj4UnsY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9Y2J4	uniprotkb:Q99344	intact:EBI-746752|intact:EBI-28986657|ensembl:ENSP00000409999|uniprotkb:Q53EP1|uniprotkb:Q96F99|uniprotkb:Q9UKB4|uniprotkb:A8K6F1|uniprotkb:B7Z5Q1|uniprotkb:E9PHW3	intact:EBI-37997|uniprotkb:D6W470|uniprotkb:E9P8X1|ensemblfungi:YPR066W	psi-mi:amol2_human(display_long)|uniprotkb:Leman coiled-coil protein(gene name synonym)|uniprotkb:AMOTL2(gene name)|psi-mi:AMOTL2(display_short)|uniprotkb:KIAA0989(gene name synonym)	psi-mi:uba3_yeast(display_long)|uniprotkb:Ubiquitin-activating enzyme E1 3(gene name synonym)|uniprotkb:RUB1-activating enzyme E1(gene name synonym)|uniprotkb:Ubiquitin-like protein-activating enzyme(gene name synonym)|uniprotkb:UBA3(gene name)|psi-mi:UBA3(display_short)|uniprotkb:YPR066W(locus name)|uniprotkb:YP9499.21(orf name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11537708|imex:IM-24995-1610	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001265612.1|refseq:NP_001265614.1|ensembl:ENSG00000114019(gene)|refseq:XP_006713717.1|refseq:NP_057285.3|refseq:XP_011511183.1|ensembl:ENST00000422605(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0003365"(establishment of cell polarity involved in ameboidal cell migration)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0035329"(hippo signaling)|go:"GO:0055037"(recycling endosome)|interpro:IPR009114(Angiomotin)|interpro:IPR024646|mint:Q9Y2J4|reactome:R-HSA-2028269|refseq:XP_016862069.1|refseq:XP_016862070.1|refseq:XP_016862071.1|ensembl:ENST00000249883|ensembl:ENSP00000249883|ensembl:ENSP00000409999|ensembl:ENST00000513145|ensembl:ENSP00000425475|ensembl:ENST00000514516|ensembl:ENSP00000424765|dip:DIP-57510N|entrezgene/locuslink:51421(identity)	refseq:NP_015391.1|sgd:S000006270|ensemblfungi:YPR066W(gene)|ensemblfungi:YPR066W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0019781"(NEDD8 activating enzyme activity)|go:"GO:0032446"(protein modification by small protein conjugation)|go:"GO:0045116"(protein neddylation)|interpro:IPR000594(UBA/THIF-type NAD/FAD binding fold)|interpro:IPR023318|interpro:IPR030468|interpro:IPR033127|dip:DIP-1719N|interpro:IPR035985|reactome:R-SCE-983168|sgd:YPR066W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:SHtKAcLLnTpSSLwVE7yQ1WECoZk9606	rogid:W38WpbRWXZjHVLC7ECqtRkmDBpI559292	intact-crc:3E8F9285CDE8E6CD|rigid:W4gM1LLSUF8w2gQk797gpk3Abkc	false	sufficient binding region:314-779	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q99380	uniprotkb:O43765	intact:EBI-12689|uniprotkb:D6VRC4|ensemblfungi:YDL232W	intact:EBI-347996|ensembl:ENSP00000221566|ensembl:ENSP00000503397|ensembl:ENSP00000504495|uniprotkb:Q9BTZ9|intact:EBI-1045243|uniprotkb:Q6FIA9|uniprotkb:D6W610	psi-mi:ost4_yeast(display_long)|uniprotkb:OST4(gene name)|psi-mi:OST4(display_short)|uniprotkb:Oligosaccharyl transferase 4 kDa subunit(gene name synonym)|uniprotkb:YDL232W(locus name)	psi-mi:sgta_human(display_long)|uniprotkb:SGTA(gene name)|psi-mi:SGTA(display_short)|uniprotkb:SGT(gene name synonym)|uniprotkb:Alpha-SGT(gene name synonym)|uniprotkb:Vpu-binding protein(gene name synonym)|uniprotkb:SGT1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11537719|imex:IM-24995-1611	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YDL232W(gene)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0008250"(oligosaccharyltransferase complex)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030674"(protein-macromolecule adaptor activity)|interpro:IPR018943|interpro:IPR036330|rcsb pdb:1RKL|rcsb pdb:6C26|rcsb pdb:6EZN|ensemblfungi:YDL232W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|refseq:NP_010049.1|sgd:S000002391|dip:DIP-2457N|sgd:YDL232W(identity)	rcsb pdb:4CPG|rcsb pdb:4GOD|rcsb pdb:4GOE|rcsb pdb:4GOF|reactome:R-HSA-9609523|rcsb pdb:2VYI|ensembl:ENSG00000104969(gene)|ensembl:ENST00000221566(transcript)|ensembl:ENST00000676943(transcript)|ensembl:ENST00000677149(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072380"(TRC complex)|go:"GO:0098850"(extrinsic component of synaptic vesicle membrane)|go:"GO:1903070"(negative regulation of ER-associated ubiquitin-dependent protein catabolic process)|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)|go:"GO:1903646"(positive regulation of chaperone-mediated protein folding)|go:"GO:1904288"(BAT3 complex binding)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR032374|mint:O43765|refseq:XP_011526480.1|refseq:NP_003012.1|entrezgene/locuslink:6449(identity)	-	crc64:BA14A9C3B197F12A	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:JOKTdHukiAM2CO87EYm3TT8UxDQ559292	rogid:r/Cyj4UJk/cS8QdrbjhTZMPCigI9606	intact-crc:7141072689D1D2C1|rigid:AZC00OrV2+nxyUj43yl1ONPojW4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96EQ0	uniprotkb:Q99380	intact:EBI-744081|ensembl:ENSP00000370395	intact:EBI-12689|uniprotkb:D6VRC4|ensemblfungi:YDL232W	psi-mi:sgtb_human(display_long)|uniprotkb:Beta-SGT(gene name synonym)|uniprotkb:Small glutamine-rich protein with tetratricopeptide repeats 2(gene name synonym)|uniprotkb:SGTB(gene name)|psi-mi:SGTB(display_short)|uniprotkb:SGT2(gene name synonym)	psi-mi:ost4_yeast(display_long)|uniprotkb:OST4(gene name)|psi-mi:OST4(display_short)|uniprotkb:Oligosaccharyl transferase 4 kDa subunit(gene name synonym)|uniprotkb:YDL232W(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11537728|imex:IM-24995-1612	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_061945.1|refseq:XP_005248605.1|ensembl:ENSG00000197860(gene)|ensembl:ENST00000381007(transcript)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0072380"(TRC complex)|go:"GO:1903646"(positive regulation of chaperone-mediated protein folding)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR032374|entrezgene/locuslink:54557(identity)	ensemblfungi:YDL232W(gene)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0008250"(oligosaccharyltransferase complex)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030674"(protein-macromolecule adaptor activity)|interpro:IPR018943|interpro:IPR036330|rcsb pdb:1RKL|rcsb pdb:6C26|rcsb pdb:6EZN|ensemblfungi:YDL232W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|refseq:NP_010049.1|sgd:S000002391|dip:DIP-2457N|sgd:YDL232W(identity)	-	-	crc64:BA14A9C3B197F12A	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:emIgH8U/yVmXT00Ty9yybIqQqas9606	rogid:JOKTdHukiAM2CO87EYm3TT8UxDQ559292	intact-crc:3A4FF86F8ADEE599|rigid:gJrsNUC7PlhReDpRaF6wp5nPNLo	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38159	uniprotkb:Q99383	intact:EBI-743526|ensembl:ENSP00000359645|uniprotkb:Q5JQ67|uniprotkb:Q969R3|uniprotkb:D3DWH0|uniprotkb:E9PG86|uniprotkb:Q8N8Y7|uniprotkb:B4E3U4	intact:EBI-11783|uniprotkb:Q02741|ensemblfungi:YOL123W|uniprotkb:D6W1U5	psi-mi:rbmx_human(display_long)|uniprotkb:Glycoprotein p43(gene name synonym)|uniprotkb:RBMX(gene name)|psi-mi:RBMX(display_short)|uniprotkb:HNRPG(gene name synonym)|uniprotkb:RBMXP1(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein G(gene name synonym)	psi-mi:hrp1_yeast(display_long)|uniprotkb:YOL123W(locus name)|uniprotkb:HRP1(gene name)|psi-mi:HRP1(display_short)|uniprotkb:NAB4(gene name synonym)|uniprotkb:NAB5(gene name synonym)|uniprotkb:Cleavage factor IB(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11537737|imex:IM-24995-1613	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000147274(gene)|ensembl:ENST00000320676(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000791"(euchromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0044530"(supraspliceosomal complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0006509"(membrane protein ectodomain proteolysis)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012604(RBM1CTR)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|mint:P38159|rcsb pdb:2MB0|rcsb pdb:2MKS|reactome:R-HSA-72163|reactome:R-HSA-72203|reactome:R-HSA-9013418|reactome:R-HSA-9013422|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273|refseq:NP_002130.2|refseq:NP_001158275.1|dip:DIP-34447N|entrezgene/locuslink:27316(identity)	ensemblfungi:YOL123W(gene)|ensemblfungi:YOL123W_mRNA(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005849"(mRNA cleavage factor complex)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0072423"(response to DNA damage checkpoint signaling)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034155|interpro:IPR034156|interpro:IPR035979|rcsb pdb:2CJK|rcsb pdb:2KM8|go:"GO:0005737"(cytoplasm)|refseq:NP_014518.1|sgd:S000005483|dip:DIP-1371N|sgd:YOL123W(identity)	-	-	crc64:1B231069437B093D	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:ocCkdy9PxjeVLUQf0tMVCEhFfO89606	rogid:8EWzxKR7UWoJhDGSB/0C2d0Qn6k559292	intact-crc:5C364D4B3EBF6589|rigid:cUrutqqJPJxYJQwe6Pf/PkZWYfc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q15415	uniprotkb:Q99383	intact:EBI-8642021|uniprotkb:B2R916|intact:MINT-8163253|ensembl:ENSP00000250831|ensembl:ENSP00000307155	intact:EBI-11783|uniprotkb:Q02741|ensemblfungi:YOL123W|uniprotkb:D6W1U5	psi-mi:rby1f_human(display_long)|uniprotkb:RBMY1F(gene name)|psi-mi:RBMY1F(display_short)|uniprotkb:RBMY1J(gene name)|psi-mi:RBMY1J(display_short)|uniprotkb:Y chromosome RNA recognition motif 2(gene name synonym)|uniprotkb:YRRM2(gene name synonym)	psi-mi:hrp1_yeast(display_long)|uniprotkb:YOL123W(locus name)|uniprotkb:HRP1(gene name)|psi-mi:HRP1(display_short)|uniprotkb:NAB4(gene name synonym)|uniprotkb:NAB5(gene name synonym)|uniprotkb:Cleavage factor IB(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11537746|imex:IM-24995-1614	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001290339.1|refseq:NP_001006117.2|refseq:NP_689798.1|ensembl:ENSG00000169800(gene)|ensembl:ENSG00000226941(gene)|ensembl:ENST00000250831(transcript)|ensembl:ENST00000303766(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016607"(nuclear speck)|go:"GO:0042802"(identical protein binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012604(RBM1CTR)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|entrezgene/locuslink:159163(identity)	ensemblfungi:YOL123W(gene)|ensemblfungi:YOL123W_mRNA(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005849"(mRNA cleavage factor complex)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0072423"(response to DNA damage checkpoint signaling)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034155|interpro:IPR034156|interpro:IPR035979|rcsb pdb:2CJK|rcsb pdb:2KM8|go:"GO:0005737"(cytoplasm)|refseq:NP_014518.1|sgd:S000005483|dip:DIP-1371N|sgd:YOL123W(identity)	-	comment:mint	crc64:1B231069437B093D	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:lEyv+LmtOFRifaC5g6jDlh5WCnM9606	rogid:8EWzxKR7UWoJhDGSB/0C2d0Qn6k559292	intact-crc:ED3CFE0760F9BF8D|rigid:307E09SLKg3CbMqdndHvbV6z96I	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:G5E962	uniprotkb:Q9URQ5	intact:EBI-11525615|ensembl:ENSP00000328177	intact:EBI-8717|ensemblfungi:YCR020W-B|uniprotkb:D6VR30	psi-mi:g5e962_human(display_long)|uniprotkb:hCG_1644200(orf name)|uniprotkb:MAGEA11(gene name)|psi-mi:MAGEA11(display_short)	psi-mi:htl1_yeast(display_long)|uniprotkb:YCR020W-B(locus name)|uniprotkb:HTL1(gene name)|psi-mi:HTL1(display_short)|uniprotkb:DRT1(gene name synonym)|uniprotkb:Chromatin structure-remodeling complex protein HTL1(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11537755|imex:IM-24995-1615	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001011544.1|ensembl:ENSG00000185247(gene)|ensembl:ENST00000333104(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016604"(nuclear body)|interpro:IPR002190(MAGE protein)|interpro:IPR021072|interpro:IPR030099|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|entrezgene/locuslink:4110(identity)	go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016586"(RSC-type complex)|rcsb pdb:6K15|rcsb pdb:6KW3|rcsb pdb:6KW4|rcsb pdb:6KW5|rcsb pdb:6TDA|rcsb pdb:6V8O|ensemblfungi:YCR020W-B(gene)|ensemblfungi:YCR020W-B_mRNA(transcript)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0005634"(nucleus)|rcsb pdb:6V92|refseq:NP_009949.1|sgd:S000006439|mint:Q9URQ5|sgd:YCR020W-B(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:sVB0aA6yibWUx/d2SE+pwpKKgtI9606	rogid:Le5HdUusNnY+/Cgn/WyISowVdbs559292	intact-crc:5C4D385A8E283BB4|rigid:MnNibLqcnWogRNb0/1fThCATswY	false	sufficient binding region:82-400	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9Y294	uniprotkb:P02309	intact:EBI-749553|uniprotkb:Q6IA08|uniprotkb:Q9P014|ensembl:ENSP00000229595	intact:EBI-8113|uniprotkb:D6VQ10|ensemblfungi:YBR009C|ensemblfungi:YNL030W	psi-mi:asf1a_human(display_long)|uniprotkb:Anti-silencing function protein 1 homolog A(gene name synonym)|uniprotkb:CCG1-interacting factor A(gene name synonym)|uniprotkb:ASF1A(gene name)|psi-mi:ASF1A(display_short)|uniprotkb:CGI-98(orf name)|uniprotkb:HSPC146(orf name)	psi-mi:h4_yeast(display_long)|uniprotkb:N2752(orf name)|uniprotkb:YBR0122(orf name)|uniprotkb:YBR009C(locus name)|uniprotkb:YNL030W(locus name)|uniprotkb:HHF1(gene name)|psi-mi:HHF1(display_short)|uniprotkb:HHF2(gene name)|psi-mi:HHF2(display_short)	psi-mi:"MI:0398"(two hybrid pooling approach)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11559978|imex:IM-24995-4894	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_054753.1|dip:DIP-29241N|ensembl:ENSG00000111875(gene)|ensembl:ENST00000229595(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0042692"(muscle cell differentiation)|interpro:IPR006818(Anti-silencing protein, ASF1-like)|interpro:IPR036747|mint:Q9Y294|rcsb pdb:1TEY|rcsb pdb:2I32|rcsb pdb:2IIJ|rcsb pdb:2IO5|rcsb pdb:3AAD|rcsb pdb:5C3I|rcsb pdb:6F0G|rcsb pdb:6F0H|rcsb pdb:6ZUF|reactome:R-HSA-2559584|rcsb pdb:6F0F|entrezgene/locuslink:25842(identity)	refseq:NP_009563.1|refseq:NP_014368.1|sgd:S000000213|sgd:S000004975|dip:DIP-418N|mint:P02309|ensemblfungi:YBR009C(gene)|ensemblfungi:YBR009C_mRNA(transcript)|ensemblfungi:YNL030W(gene)|ensemblfungi:YNL030W_mRNA(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0006333"(chromatin assembly or disassembly)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0034729"(histone H3-K79 methylation)|go:"GO:0043935"(sexual sporulation resulting in formation of a cellular spore)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0061587"(transfer RNA gene-mediated silencing)|interpro:IPR001951(Histone H4)|interpro:IPR009072(Histone-fold)|interpro:IPR019809|interpro:IPR035425|rcsb pdb:1E6I|rcsb pdb:1ID3|rcsb pdb:1Q1A|rcsb pdb:1SZC|rcsb pdb:1SZD|rcsb pdb:2DVQ|rcsb pdb:2DVR|rcsb pdb:2E3K|rcsb pdb:2FSB|rcsb pdb:2H2H|rcsb pdb:2L5A|rcsb pdb:2QQF|rcsb pdb:2QQG|rcsb pdb:3TO6|rcsb pdb:4JJN|rcsb pdb:4KUD|rcsb pdb:4PSX|rcsb pdb:4TWI|rcsb pdb:4TWJ|rcsb pdb:5W0V|rcsb pdb:5ZBA|rcsb pdb:5ZBB|rcsb pdb:6GEJ|rcsb pdb:6GEN|rcsb pdb:6QLD|rcsb pdb:6RXJ|rcsb pdb:6RXK|rcsb pdb:6RXL|rcsb pdb:6RXM|rcsb pdb:6RXO|rcsb pdb:6RXP|rcsb pdb:6RXQ|rcsb pdb:6RXR|rcsb pdb:7K78|rcsb pdb:7K7G|reactome:R-SCE-2299718|reactome:R-SCE-2559580|reactome:R-SCE-3214842|reactome:R-SCE-3214847|reactome:R-SCE-3214858|reactome:R-SCE-4551638|reactome:R-SCE-9018519|sgd:YBR009C(identity)|sgd:YNL030W(identity)	-	caution:This sequence has been withdrawn from Uniprot.	crc64:69B7D1F89E62DE41	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:rIMptRSOYD+wfp0dMEHjhNNsHXQ9606	rogid:wGtUrumyxGKsW9BEzkBW3FwvwUo559292	rigid:CcW8ft9xR+nvB26MswK/6i200ZQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
intact:EBI-11522238	uniprotkb:O14641	-	intact:EBI-740850|ensembl:ENSP00000005340|uniprotkb:Q53XM0|uniprotkb:D3DTN3	psi-mi:cyc2(display_short)|psi-mi:EBI-11522238(display_long)	psi-mi:dvl2_human(display_long)|uniprotkb:DSH homolog 2(gene name synonym)|uniprotkb:DVL2(gene name)|psi-mi:DVL2(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11537790|imex:IM-24995-1618	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:YOR037W(identity)	refseq:NP_004413.1|ensembl:ENSG00000004975(gene)|ensembl:ENST00000005340(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005109"(frizzled binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0007507"(heart development)|go:"GO:0016235"(aggresome)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044340"(canonical Wnt signaling pathway involved in regulation of cell proliferation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0150012"(positive regulation of neuron projection arborization)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008341(Dishevelled-2 region)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:O14641|rcsb pdb:2REY|rcsb pdb:3CBX|rcsb pdb:3CBY|rcsb pdb:3CBZ|rcsb pdb:3CC0|rcsb pdb:4WIP|rcsb pdb:5LNP|rcsb pdb:5SUY|rcsb pdb:5SUZ|rcsb pdb:6IW3|rcsb pdb:6JCK|reactome:R-HSA-201681|reactome:R-HSA-201688|reactome:R-HSA-2028269|reactome:R-HSA-4086400|reactome:R-HSA-4608870|reactome:R-HSA-4641258|reactome:R-HSA-4641262|reactome:R-HSA-5099900|reactome:R-HSA-5368598|reactome:R-HSA-5663220|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9673324|ensembl:ENSP00000005340|dip:DIP-34433N|entrezgene/locuslink:1856(identity)	-	no-uniprot-update:	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:5RstlUmv8fpj9QSGrNaQaZc2OUU4932	rogid:2Vdc8oRnT4Mz/j+EXQXrL3AszOc9606	intact-crc:4BC3848B11BD1281|rigid:VJEDE9PWZ37MtC3IhzljtXXrmE0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:J3KPQ4	intact:EBI-11522220	intact:EBI-11522225	-	psi-mi:j3kpq4_human(display_long)|uniprotkb:hCG_39668(orf name)|uniprotkb:ARHGAP9(gene name)|psi-mi:ARHGAP9(display_short)	psi-mi:lsb3(display_short)|psi-mi:EBI-11522220(display_long)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11537779|imex:IM-24995-1617	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR000198(RhoGAP)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035465|refseq:NP_001306779.1|go:"GO:0005096"(GTPase activator activity)|go:"GO:0007165"(signal transduction)|interpro:IPR036020|interpro:IPR036028|entrezgene/locuslink:64333(identity)	sgd:YFR024C-A(identity)	-	-	no-uniprot-update:	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:H9MJrfHtg/AF6G6rqm+nDFz32lo9606	rogid:lsGJZWImagMoiiCZztCcxCn2LlU4932	intact-crc:9FA90FC38B165EC3|rigid:RtOoXkTmAlkeS6I+dTMX6DKn6hY	false	sufficient binding region:72-821	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
intact:EBI-11522208	uniprotkb:Q08379	-	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	psi-mi:ylr445w(display_short)|psi-mi:EBI-11522208(display_long)	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11537768|imex:IM-24995-1616	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:YLR445W(identity)	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N|entrezgene/locuslink:2801(identity)	-	no-uniprot-update:	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2017/05/26	rogid:kUe7etYjGLH6i6KZ5N2LXUnjAf04932	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	intact-crc:F09B61D4471358CC|rigid:KkBN0sQ8Zc2sadqGnr4/J3iuD1A	false	-	sufficient binding region:383-1002	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
intact:EBI-11522220	uniprotkb:P14136	-	intact:EBI-744302|uniprotkb:Q53H98|uniprotkb:Q5D055|uniprotkb:Q6ZQS3|uniprotkb:Q7Z5J6|uniprotkb:Q7Z5J7|uniprotkb:Q96KS4|uniprotkb:Q96P18|uniprotkb:Q9UFD0|uniprotkb:B2RD44|uniprotkb:D3DX59|intact:EBI-3909365|uniprotkb:E9PAX3|ensembl:ENSP00000466598|uniprotkb:A7REI1	psi-mi:lsb3(display_short)|psi-mi:EBI-11522220(display_long)	psi-mi:gfap_human(display_long)|uniprotkb:GFAP(gene name)|psi-mi:GFAP(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11537828|imex:IM-24995-1622	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:YFR024C-A(identity)	refseq:NP_001124491.1|refseq:NP_001229305.1|refseq:NP_002046.1|ensembl:ENSG00000131095(gene)|ensembl:ENST00000588735(transcript)|go:"GO:0005178"(integrin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0009611"(response to wounding)|go:"GO:0010467"(gene expression)|go:"GO:0010625"(positive regulation of Schwann cell proliferation)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0014002"(astrocyte development)|go:"GO:0019900"(kinase binding)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0031102"(neuron projection regeneration)|go:"GO:0042802"(identical protein binding)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0044297"(cell body)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0051580"(regulation of neurotransmitter uptake)|go:"GO:0060020"(Bergmann glial cell differentiation)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0070779"(D-aspartate import across plasma membrane)|go:"GO:0097450"(astrocyte end-foot)|go:"GO:0098574"(cytoplasmic side of lysosomal membrane)|go:"GO:1904714"(regulation of chaperone-mediated autophagy)|interpro:IPR006821(Intermediate filament, DNA-binding region)|interpro:IPR018039|interpro:IPR027701|interpro:IPR039008|mint:P14136|rcsb pdb:6A9P|reactome:R-HSA-1251985|reactome:R-HSA-9613829|entrezgene/locuslink:2670(identity)	-	no-uniprot-update:	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:lsGJZWImagMoiiCZztCcxCn2LlU4932	rogid:Pz4JW0WjMjBYILTDSX9jUmMqWhg9606	intact-crc:9B37B7C3B3998EE7|rigid:lWp7O9BNA3tICjiU1HeSWb4cvmo	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
intact:EBI-11522279	uniprotkb:O95994	-	intact:EBI-712648|ensembl:ENSP00000391490	psi-mi:hsp150(display_short)|psi-mi:EBI-11522279(display_long)	psi-mi:agr2_human(display_long)|uniprotkb:Secreted cement gland protein XAG-2 homolog(gene name synonym)|uniprotkb:HPC8(gene name synonym)|uniprotkb:AG2(gene name synonym)|uniprotkb:UNQ515/PRO1030(orf name)|uniprotkb:AGR2(gene name)|psi-mi:AGR2(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11537819|imex:IM-24995-1621	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:YJL159W(identity)	go:"GO:0005615"(extracellular space)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0042802"(identical protein binding)|go:"GO:0045742"(positive regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0048546"(digestive tract morphogenesis)|go:"GO:0048639"(positive regulation of developmental growth)|go:"GO:0060480"(lung goblet cell differentiation)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070254"(mucus secretion)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:1903896"(positive regulation of IRE1-mediated unfolded protein response)|go:"GO:1903899"(positive regulation of PERK-mediated unfolded protein response)|interpro:IPR036249|rcsb pdb:2LNS|rcsb pdb:2LNT|ensembl:ENSG00000106541(gene)|ensembl:ENST00000419304(transcript)|go:"GO:0002162"(dystroglycan binding)|go:"GO:0005154"(epidermal growth factor receptor binding)|refseq:NP_006399.1|refseq:XP_005249638.1|dip:DIP-48825N|entrezgene/locuslink:10551(identity)	-	no-uniprot-update:	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:6kfIxwLCGf2jj4GQK7oFLVnLfXU4932	rogid:E824a1MDXuGzk23ohjS7HAeEx5U9606	intact-crc:2F77766305410D63|rigid:6Zb01R8bdSK9bglzfjUt4aN1QpQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O43765	intact:EBI-11522265	intact:EBI-347996|ensembl:ENSP00000221566|ensembl:ENSP00000503397|ensembl:ENSP00000504495|uniprotkb:Q9BTZ9|intact:EBI-1045243|uniprotkb:Q6FIA9|uniprotkb:D6W610	-	psi-mi:sgta_human(display_long)|uniprotkb:SGTA(gene name)|psi-mi:SGTA(display_short)|uniprotkb:SGT(gene name synonym)|uniprotkb:Alpha-SGT(gene name synonym)|uniprotkb:Vpu-binding protein(gene name synonym)|uniprotkb:SGT1(gene name synonym)	psi-mi:pth2(display_short)|psi-mi:EBI-11522265(display_long)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11537810|imex:IM-24995-1620	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:4CPG|rcsb pdb:4GOD|rcsb pdb:4GOE|rcsb pdb:4GOF|reactome:R-HSA-9609523|rcsb pdb:2VYI|ensembl:ENSG00000104969(gene)|ensembl:ENST00000221566(transcript)|ensembl:ENST00000676943(transcript)|ensembl:ENST00000677149(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072380"(TRC complex)|go:"GO:0098850"(extrinsic component of synaptic vesicle membrane)|go:"GO:1903070"(negative regulation of ER-associated ubiquitin-dependent protein catabolic process)|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)|go:"GO:1903646"(positive regulation of chaperone-mediated protein folding)|go:"GO:1904288"(BAT3 complex binding)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR032374|mint:O43765|refseq:XP_011526480.1|refseq:NP_003012.1|entrezgene/locuslink:6449(identity)	sgd:YBL057C(identity)	-	-	no-uniprot-update:	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:r/Cyj4UJk/cS8QdrbjhTZMPCigI9606	rogid:pRGxsdHHpne2ORtwUYJZXHw7qPA4932	intact-crc:299D470F9797231D|rigid:Tr4HPuY4tbotOsKellP2JQdWRVc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O15156-2	intact:EBI-11522220	intact:EBI-11522250|ensembl:ENSP00000406286	-	psi-mi:o15156-2(display_long)|uniprotkb:ZBTB7B(gene name)|psi-mi:ZBTB7B(display_short)|uniprotkb:Krueppel-related zinc finger protein cKrox(gene name synonym)|uniprotkb:T-helper-inducing POZ/Krueppel-like factor(gene name synonym)|uniprotkb:ZBTB15(gene name synonym)|uniprotkb:ZFP67(gene name synonym)|uniprotkb:ZNF857B(gene name synonym)|uniprotkb:Zinc finger and BTB domain-containing protein 15(gene name synonym)|uniprotkb:Zinc finger protein 67 homolog(gene name synonym)|uniprotkb:Zinc finger protein 857B(gene name synonym)|uniprotkb:Zinc finger protein Th-POK(gene name synonym)	psi-mi:lsb3(display_short)|psi-mi:EBI-11522220(display_long)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11537799|imex:IM-24995-1619	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-740434(isoform-parent)|ensembl:ENSG00000160685(gene)|ensembl:ENST00000417934(transcript)|uniprotkb:O15156-2(isoform-parent)|entrezgene/locuslink:51043(identity)	sgd:YFR024C-A(identity)	-	isoform-comment:No experimental confirmation available.	no-uniprot-update:	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:41NEFYyprTXI+fOHVFh78TPKF289606	rogid:lsGJZWImagMoiiCZztCcxCn2LlU4932	intact-crc:9F23C6DFE43DB374|rigid:8Xzv2aOPdULdtJOvuLu4NO8LkC8	false	sufficient binding region:35-573	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P43355	intact:EBI-11522208	intact:EBI-740978|ensembl:ENSP00000349085|uniprotkb:O00346|uniprotkb:B2RC81	-	psi-mi:maga1_human(display_long)|uniprotkb:MAGE-1 antigen(gene name synonym)|uniprotkb:Antigen MZ2-E(gene name synonym)|uniprotkb:Cancer/testis antigen 1.1(gene name synonym)|uniprotkb:MAGEA1(gene name)|psi-mi:MAGEA1(display_short)|uniprotkb:MAGE1(gene name synonym)|uniprotkb:MAGE1A(gene name synonym)	psi-mi:ylr445w(display_short)|psi-mi:EBI-11522208(display_long)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11537855|imex:IM-24995-1625	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004979.3|ensembl:ENSG00000198681(gene)|ensembl:ENST00000356661(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|interpro:IPR002190(MAGE protein)|interpro:IPR021072|interpro:IPR030093|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|rcsb pdb:1W72|rcsb pdb:3BO8|dip:DIP-54794N|entrezgene/locuslink:4100(identity)	sgd:YLR445W(identity)	-	crc64:544EEB1F9F4E9D33	no-uniprot-update:	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:6XW3mnTNM3yvOtXmiFbU8Uz3hjA9606	rogid:kUe7etYjGLH6i6KZ5N2LXUnjAf04932	intact-crc:A6A39EF654C0C850|rigid:OyU+sBbEyvPELhKOadGOyFu9W4g	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:A0A6A5PPQ8	uniprotkb:P40855	intact:EBI-11522307	intact:EBI-594747|uniprotkb:Q8NI97|intact:EBI-981972|uniprotkb:Q5QNY4|uniprotkb:D3DVE7|ensembl:ENSP00000357051	psi-mi:a0a6a5ppq8_yeasx(display_long)|uniprotkb:PACBIOSEQ_LOCUS4583(orf name)|uniprotkb:PACBIOSEQ_LOCUS4587(orf name)|uniprotkb:PACBIOSEQ_LOCUS4600(orf name)|uniprotkb:PACBIOSEQ_LOCUS4626(orf name)|uniprotkb:PACBIOSEQ_LOCUS4639(orf name)|uniprotkb:PACBIOSEQ_LOCUS4679(orf name)	psi-mi:pex19_human(display_long)|uniprotkb:PEX19(gene name)|psi-mi:PEX19(display_short)|uniprotkb:HK33(gene name synonym)|uniprotkb:PXF(gene name synonym)|uniprotkb:OK/SW-cl.22(orf name)|uniprotkb:Peroxin-19(gene name synonym)|uniprotkb:Peroxisomal farnesylated protein(gene name synonym)|uniprotkb:33 kDa housekeeping protein(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11537846|imex:IM-24995-1624	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016021"(integral component of membrane)|uniprotkb:A0A250WEQ4(uniprot-removed-ac)|sgd:YMR122W-A(identity)	refseq:NP_001180573.1|refseq:NP_002848.1|dip:DIP-24172N|ensembl:ENSG00000162735(gene)|ensembl:ENST00000368072(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006625"(protein targeting to peroxisome)|go:"GO:0007031"(peroxisome organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016557"(peroxisome membrane biogenesis)|go:"GO:0016559"(peroxisome fission)|go:"GO:0031526"(brush border membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033328"(peroxisome membrane targeting sequence binding)|go:"GO:0036105"(peroxisome membrane class-1 targeting sequence binding)|go:"GO:0045046"(protein import into peroxisome membrane)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0072663"(establishment of protein localization to peroxisome)|go:"GO:0140597"(protein carrier chaperone)|go:"GO:1900131"(negative regulation of lipid binding)|interpro:IPR006708(Pex19 protein)|interpro:IPR038322|mint:P40855|rcsb pdb:2W85|rcsb pdb:2WL8|rcsb pdb:3AJB|rcsb pdb:3MK4|rcsb pdb:5LNF|reactome:R-HSA-1369062|reactome:R-HSA-9603798|entrezgene/locuslink:5824(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:f+RZksZwcG8Xqd6IVrksanQ54vE4932	rogid:yNnX2hPPJ7miGaz2Req0qFn0L189606	intact-crc:0B1BA0DE8AFCA34C|rigid:ygWK9jcKDtOt4y7w3JAAtKGOTWE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P14317	intact:EBI-11522220	intact:EBI-750369|uniprotkb:B4DQ69|uniprotkb:Q53Y93|uniprotkb:Q6IBK9|uniprotkb:Q9UDK0|ensembl:ENSP00000320176	-	psi-mi:hcls1_human(display_long)|uniprotkb:Hematopoietic cell-specific LYN substrate 1(gene name synonym)|uniprotkb:LckBP1(gene name synonym)|uniprotkb:p75(gene name synonym)|uniprotkb:HCLS1(gene name)|psi-mi:HCLS1(display_short)|uniprotkb:HS1(gene name synonym)	psi-mi:lsb3(display_short)|psi-mi:EBI-11522220(display_long)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11537837|imex:IM-24995-1623	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000320176|ensembl:ENST00000495491|ensembl:ENSP00000418299|refseq:NP_001278970.1|refseq:NP_005326.2|ensembl:ENSG00000180353(gene)|ensembl:ENST00000314583(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009725"(response to hormone)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030427"(site of polarized growth)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030854"(positive regulation of granulocyte differentiation)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045651"(positive regulation of macrophage differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0051015"(actin filament binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:2000107"(negative regulation of leukocyte apoptotic process)|go:"GO:2000251"(positive regulation of actin cytoskeleton reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR003134(Hs1/Cortactin)|interpro:IPR028534|interpro:IPR036028|mint:P14317|entrezgene/locuslink:3059(identity)	sgd:YFR024C-A(identity)	-	-	no-uniprot-update:	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:sViasWf8ZiLb/dmYn3VEr7t2L0Y9606	rogid:lsGJZWImagMoiiCZztCcxCn2LlU4932	intact-crc:8247C14C7545E4C5|rigid:pFBbhqbSkpRlbGtTdrie/j+YySs	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q13829	intact:EBI-11522371	intact:EBI-2505861|uniprotkb:B7Z6M4|uniprotkb:Q5TZQ1|ensembl:ENSP00000226225	-	psi-mi:bacd2_human(display_long)|uniprotkb:BACURD2(gene name synonym)|uniprotkb:BTB/POZ domain-containing protein TNFAIP1(gene name synonym)|uniprotkb:Protein B12(gene name synonym)|uniprotkb:TNFAIP1(gene name)|psi-mi:TNFAIP1(display_short)|uniprotkb:EDP1(gene name synonym)|uniprotkb:Tumor necrosis factor, alpha-induced protein 1, endothelial(gene name synonym)	psi-mi:yjr003c(display_short)|psi-mi:EBI-11522371(display_long)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11537909|imex:IM-24995-1631	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_066960.1|ensembl:ENSG00000109079(gene)|ensembl:ENST00000226225(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006955"(immune response)|go:"GO:0016477"(cell migration)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030332"(cyclin binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0043149"(stress fiber assembly)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0051260"(protein homooligomerization)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR003131(Potassium channel, voltage dependent, Kv,  tetramerisation)|interpro:IPR011333(BTB/POZ fold)|mint:Q13829|reactome:R-HSA-9696264|reactome:R-HSA-9696270|entrezgene/locuslink:7126(identity)	sgd:YJR003C(identity)	-	-	no-uniprot-update:	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:8vM9HnNmkirDbJRETV/TeE8pONY9606	rogid:dYGrrP3JnrXO2rj4v/nTT64la6A4932	intact-crc:C3DCAA7C638E1847|rigid:9a3A/8NdlJMCCNvngc0qbz5NaMk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q13422-7	intact:EBI-11522371	intact:EBI-11522367|ensembl:ENSP00000352123|ensembl:ENSP00000413025	-	psi-mi:q13422-7(display_long)|uniprotkb:IKZF1(gene name)|psi-mi:IKZF1(display_short)|uniprotkb:IK1(gene name synonym)|uniprotkb:IKAROS(gene name synonym)|uniprotkb:Ikaros family zinc finger protein 1(gene name synonym)|uniprotkb:LYF1(gene name synonym)|uniprotkb:Lymphoid transcription factor LyF-1(gene name synonym)|uniprotkb:ZNFN1A1(gene name synonym)	psi-mi:yjr003c(display_short)|psi-mi:EBI-11522371(display_long)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11537900|imex:IM-24995-1630	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-745305(isoform-parent)|ensembl:ENSG00000185811(gene)|ensembl:ENST00000359197(transcript)|ensembl:ENST00000439701(transcript)|uniprotkb:Q13422-7(isoform-parent)|entrezgene/locuslink:10320(identity)	sgd:YJR003C(identity)	-	-	no-uniprot-update:	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:ou/ovXYoMneBNVp4pj38VxenfyY9606	rogid:dYGrrP3JnrXO2rj4v/nTT64la6A4932	intact-crc:EA62B6C29F442269|rigid:E0mitkr1eJGaEWkr0L13/d3MwQw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
intact:EBI-11522220	uniprotkb:Q13191	-	intact:EBI-744027|uniprotkb:Q63Z43|uniprotkb:A8K9S7|uniprotkb:Q13192|uniprotkb:Q13193|uniprotkb:Q3LIC0|uniprotkb:Q8IVC5|uniprotkb:B7WNM4|intact:EBI-28969458|ensembl:ENSP00000377598|intact:EBI-8051403|intact:MINT-7907019	psi-mi:lsb3(display_short)|psi-mi:EBI-11522220(display_long)	psi-mi:cblb_human(display_long)|uniprotkb:Signal transduction protein CBL-B(gene name synonym)|uniprotkb:SH3-binding protein CBL-B(gene name synonym)|uniprotkb:Casitas B-lineage lymphoma proto-oncogene b(gene name synonym)|uniprotkb:RING finger protein 56(gene name synonym)|uniprotkb:CBLB(gene name)|psi-mi:CBLB(display_short)|uniprotkb:RNF56(gene name synonym)|uniprotkb:Nbla00127(orf name)|uniprotkb:RING-type E3 ubiquitin transferase CBL-B(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11537891|imex:IM-24995-1629	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:YFR024C-A(identity)	refseq:NP_733762.2|refseq:NP_001308717.1|ensembl:ENSP00000377598|ensembl:ENST00000403724|ensembl:ENSP00000384816|ensembl:ENST00000405772|ensembl:ENSP00000384938|refseq:XP_011511559.1|ensembl:ENSG00000114423(gene)|ensembl:ENST00000394030(transcript)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0002669"(positive regulation of T cell anergy)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0007175"(negative regulation of epidermal growth factor-activated receptor activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0018193"(peptidyl-amino acid modification)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0005829"(cytosol)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042110"(T cell activation)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046642"(negative regulation of alpha-beta T cell proliferation)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050860"(negative regulation of T cell receptor signaling pathway)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:2000583"(regulation of platelet-derived growth factor receptor-alpha signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003153(Adaptor protein Cbl, N-terminal helical)|interpro:IPR011992(EF-Hand type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014742(Adaptor protein Cbl, SH2-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR017907|interpro:IPR024159|interpro:IPR024162|interpro:IPR036537|interpro:IPR036860|interpro:IPR039520|mint:Q13191|rcsb pdb:2AK5|rcsb pdb:2BZ8|rcsb pdb:2DO6|rcsb pdb:2J6F|rcsb pdb:2JNH|rcsb pdb:2LDR|rcsb pdb:2OOA|rcsb pdb:2OOB|rcsb pdb:3PFV|rcsb pdb:3VGO|rcsb pdb:3ZNI|reactome:R-HSA-983168|interpro:IPR014741(Adaptor protein Cbl, EF hand-like)|dip:DIP-33091N|entrezgene/locuslink:868(identity)	-	no-uniprot-update:	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:lsGJZWImagMoiiCZztCcxCn2LlU4932	rogid:cJ5eLH0TMyM6OtmS1sM3rhsrsIk9606	intact-crc:2F7FAF333105B156|rigid:b4mXxgUlwqy89aav6wvlaaGSutc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P63279	intact:EBI-11522346	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	-	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:ctt1(display_short)|psi-mi:EBI-11522346(display_long)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11537882|imex:IM-24995-1628	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N|entrezgene/locuslink:7329(identity)	sgd:YGR088W(identity)	-	-	no-uniprot-update:	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	rogid:jNEGATUEb58kyyOUWh6Xi7tJTk04932	intact-crc:1A70D279E71E85DA|rigid:ZzCTm/J4wYAeXTuzTojCTEMWyUo	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P51116	intact:EBI-11522220	intact:EBI-740459|uniprotkb:Q8WUM2|uniprotkb:Q86V09|uniprotkb:B2R9M2|uniprotkb:D3DTQ1|ensembl:ENSP00000250113	-	psi-mi:fxr2_human(display_long)|uniprotkb:FXR2(gene name)|psi-mi:FXR2(display_short)|uniprotkb:FMR1L2(gene name synonym)	psi-mi:lsb3(display_short)|psi-mi:EBI-11522220(display_long)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11537873|imex:IM-24995-1627	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR004087(K Homology)|refseq:NP_004851.2|ensembl:ENSG00000129245(gene)|ensembl:ENST00000250113(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0044326"(dendritic spine neck)|go:"GO:0045182"(translation regulator activity)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0098793"(presynapse)|go:"GO:1902737"(dendritic filopodium)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|interpro:IPR004088(K Homology, type 1)|interpro:IPR008395(Agenet)|interpro:IPR022034|interpro:IPR032172|interpro:IPR036612|interpro:IPR040148|interpro:IPR040472|interpro:IPR041560|mint:P51116|rcsb pdb:3H8Z|entrezgene/locuslink:9513(identity)	sgd:YFR024C-A(identity)	-	-	no-uniprot-update:	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:NnYgyzD2NRGIO1ZHukr5qy44qRE9606	rogid:lsGJZWImagMoiiCZztCcxCn2LlU4932	intact-crc:A94708C944A459BD|rigid:Ip2hgPhCGE2zPYgJQ9/bnSugGCk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
intact:EBI-11522208	uniprotkb:P43358	-	intact:EBI-743122|ensembl:ENSP00000276344|ensembl:ENSP00000353379|ensembl:ENSP00000359360|ensembl:ENSP00000359365|ensembl:ENSP00000377497|ensembl:ENSP00000377498|ensembl:ENSP00000394149|ensembl:ENSP00000402186|ensembl:ENSP00000506838|ensembl:ENSP00000507023|uniprotkb:Q14798	psi-mi:ylr445w(display_short)|psi-mi:EBI-11522208(display_long)	psi-mi:maga4_human(display_long)|uniprotkb:MAGE-4 antigen(gene name synonym)|uniprotkb:MAGE-X2 antigen(gene name synonym)|uniprotkb:MAGE-41 antigen(gene name synonym)|uniprotkb:Cancer/testis antigen 1.4(gene name synonym)|uniprotkb:MAGEA4(gene name)|psi-mi:MAGEA4(display_short)|uniprotkb:MAGE4(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11537864|imex:IM-24995-1626	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:YLR445W(identity)	ensembl:ENSG00000147381(gene)|ensembl:ENST00000276344(transcript)|ensembl:ENST00000360243(transcript)|ensembl:ENST00000370335(transcript)|ensembl:ENST00000370340(transcript)|ensembl:ENST00000393920(transcript)|ensembl:ENST00000393921(transcript)|ensembl:ENST00000430273(transcript)|ensembl:ENST00000457310(transcript)|ensembl:ENST00000682265(transcript)|ensembl:ENST00000684668(transcript)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045787"(positive regulation of cell cycle)|interpro:IPR002190(MAGE protein)|interpro:IPR021072|interpro:IPR030098|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|mint:P43358|rcsb pdb:1I4F|rcsb pdb:2WA0|rcsb pdb:6TRN|rcsb pdb:6TRO|refseq:NP_001011548.1|refseq:NP_001011549.1|refseq:NP_001011550.1|refseq:NP_002353.3|refseq:XP_005274735.1|refseq:XP_005274736.1|entrezgene/locuslink:4103(identity)	-	no-uniprot-update:	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:kUe7etYjGLH6i6KZ5N2LXUnjAf04932	rogid:wF193QbpesCr14OlGMQD+BabWvs9606	intact-crc:C6453811C0E865A3|rigid:MdsWg7Q3c+qYxXgxDIdBhk0IZso	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
intact:EBI-11522371	uniprotkb:Q5JR59-3	-	intact:EBI-11522433|ensembl:ENSP00000370186	psi-mi:yjr003c(display_short)|psi-mi:EBI-11522371(display_long)	psi-mi:q5jr59-3(display_long)|uniprotkb:MTUS2(gene name)|psi-mi:MTUS2(display_short)|uniprotkb:CAZIP(gene name synonym)|uniprotkb:Cardiac zipper protein(gene name synonym)|uniprotkb:KIAA0774(gene name synonym)|uniprotkb:Microtubule plus-end tracking protein TIP150(gene name synonym)|uniprotkb:TIP150(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11537954|imex:IM-24995-1636	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:YJR003C(identity)	ensembl:ENSG00000132938(gene)|ensembl:ENST00000380808(transcript)|intact:EBI-742948(isoform-parent)|uniprotkb:Q5JR59-3(isoform-parent)|entrezgene/locuslink:23281(identity)	-	no-uniprot-update:	isoform-comment:No experimental confirmation available.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:dYGrrP3JnrXO2rj4v/nTT64la6A4932	rogid:npId9tC7VoLN/jteoBiRbSYChPs9606	intact-crc:9DB0372B321D61C5|rigid:/VcQ18j57lmRaJc5lZLRViDVBO8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q53EZ4	intact:EBI-11522371	intact:EBI-747776|uniprotkb:Q32WF5|uniprotkb:Q3MV20|uniprotkb:Q5VY28|uniprotkb:Q6N034|ensembl:ENSP00000360540|uniprotkb:Q96H32|uniprotkb:Q9NVS7|uniprotkb:B2RDG8|intact:EBI-10173536|uniprotkb:D3DR37|intact:EBI-28973801	-	psi-mi:cep55_human(display_long)|uniprotkb:Up-regulated in colon cancer 6(gene name synonym)|uniprotkb:CEP55(gene name)|psi-mi:CEP55(display_short)|uniprotkb:URCC6(gene name synonym)|uniprotkb:C10orf3(gene name synonym)	psi-mi:yjr003c(display_short)|psi-mi:EBI-11522371(display_long)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11537945|imex:IM-24995-1635	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001120654.1|refseq:NP_060601.3|ensembl:ENSG00000138180(gene)|ensembl:ENST00000371485(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0014066"(regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0030496"(midbody)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042802"(identical protein binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0061952"(midbody abscission)|go:"GO:0090543"(Flemming body)|go:"GO:1904888"(cranial skeletal system development)|interpro:IPR022008|interpro:IPR038926|mint:Q53EZ4|rcsb pdb:3E1R|rcsb pdb:3WUT|rcsb pdb:3WUU|rcsb pdb:3WUV|go:"GO:0005814"(centriole)|ensembl:ENSP00000360540|dip:DIP-44581N|entrezgene/locuslink:55165(identity)	sgd:YJR003C(identity)	-	-	no-uniprot-update:	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:tuo36vVb8ZgPDR81YjZFNEg559w9606	rogid:dYGrrP3JnrXO2rj4v/nTT64la6A4932	intact-crc:141C3F7ED3177FC1|rigid:Ziq/qA2vX/etQxiTQCosKuYngCs	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q16637-3	intact:EBI-11522403	intact:EBI-395447|ensembl:ENSP00000424926|ensembl:ENSP00000486152|ensembl:ENSP00000487015|ensembl:ENSP00000487029|intact:EBI-8628183|intact:MINT-95595	-	psi-mi:q16637-3(display_long)|uniprotkb:Iso7-SMN(isoform synonym)|uniprotkb:SMN1(gene name)|psi-mi:SMN1(display_short)|uniprotkb:SMN2(gene name)|psi-mi:SMN2(display_short)|uniprotkb:SMN(gene name synonym)|uniprotkb:SMNT(gene name synonym)|uniprotkb:SMNC(gene name synonym)|uniprotkb:Component of gems 1(gene name synonym)|uniprotkb:Gemin-1(gene name synonym)	psi-mi:nhp2(display_short)|psi-mi:EBI-11522403(display_long)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11537936|imex:IM-24995-1634	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-395421(smn_human)|ensembl:ENSG00000275349(gene)|ensembl:ENST00000506163(transcript)|ensembl:ENST00000626847(transcript)|ensembl:ENST00000628353(transcript)|ensembl:ENST00000628642(transcript)|ensembl:ENSG00000172062(gene)|ensembl:ENSG00000205571(gene)|ensembl:ENSG00000273772(gene)|uniprotkb:Q16637-3(isoform-parent)|entrezgene/locuslink:6607(identity)	sgd:YDL208W(identity)	-	isoform-comment:Thought to be a non-functional protein that lacks the capacity to oligomerize and thus cannot interact with Sm proteins. Primarily derived from SMN2 gene.	no-uniprot-update:	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:ICA63eidVxJ219M+YZJ20zNh+xU9606	rogid:FFduCSFjK3s7VNWPyW67FjyPE7Y4932	intact-crc:49A672A3BD33C0A6|rigid:F+LPh6d3R3r87DAdu/iZ1G3pXbA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
intact:EBI-11522403	uniprotkb:Q16637	-	intact:EBI-395421|uniprotkb:Q13119|uniprotkb:Q549U5|uniprotkb:Q96J51|ensembl:ENSP00000305857|uniprotkb:A8K0V4|ensembl:ENSP00000370083|ensembl:ENSP00000370117|ensembl:ENSP00000370119|ensembl:ENSP00000479920|ensembl:ENSP00000482966|ensembl:ENSP00000483515|ensembl:ENSP00000483819|ensembl:ENSP00000487206|ensembl:ENSP00000487421	psi-mi:nhp2(display_short)|psi-mi:EBI-11522403(display_long)	psi-mi:smn_human(display_long)|uniprotkb:SMN1(gene name)|psi-mi:SMN1(display_short)|uniprotkb:SMN(gene name synonym)|uniprotkb:SMNT(gene name synonym)|uniprotkb:SMN2(gene name)|psi-mi:SMN2(display_short)|uniprotkb:SMNC(gene name synonym)|uniprotkb:Component of gems 1(gene name synonym)|uniprotkb:Gemin-1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11537927|imex:IM-24995-1633	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:YDL208W(identity)	refseq:NP_000335.1|refseq:NP_059107.1|refseq:NP_075012.1|refseq:NP_075013.1|refseq:NP_075014.1|refseq:NP_075015.1|ensembl:ENSG00000172062(gene)|ensembl:ENSG00000205571(gene)|ensembl:ENSG00000273772(gene)|ensembl:ENSG00000275349(gene)|ensembl:ENSG00000277773(gene)|ensembl:ENST00000351205(transcript)|ensembl:ENST00000380707(transcript)|ensembl:ENST00000380741(transcript)|ensembl:ENST00000380743(transcript)|ensembl:ENST00000614610(transcript)|ensembl:ENST00000618251(transcript)|ensembl:ENST00000618661(transcript)|ensembl:ENST00000622739(transcript)|ensembl:ENST00000627341(transcript)|ensembl:ENST00000629122(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0007399"(nervous system development)|go:"GO:0015030"(Cajal body)|go:"GO:0016604"(nuclear body)|go:"GO:0030018"(Z disc)|go:"GO:0030424"(axon)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043204"(perikaryon)|go:"GO:0097504"(Gemini of coiled bodies)|interpro:IPR002999(Tudor)|interpro:IPR010304(Survival motor neuron)|mint:Q16637|rcsb pdb:1G5V|rcsb pdb:1MHN|rcsb pdb:2LEH|rcsb pdb:4A4E|rcsb pdb:4A4G|rcsb pdb:4GLI|rcsb pdb:4QQ6|rcsb pdb:5XJL|go:"GO:0034719"(SMN-Sm protein complex)|rcsb pdb:5XJQ|rcsb pdb:5XJR|rcsb pdb:5XJS|rcsb pdb:5XJT|rcsb pdb:5XJU|reactome:R-HSA-191859|go:"GO:0032797"(SMN complex)|refseq:NP_001284644.1|ensembl:ENSP00000305857|ensembl:ENSP00000370083|ensembl:ENSP00000370117|ensembl:ENST00000380742|ensembl:ENSP00000370118|ensembl:ENSP00000370119|ensembl:ENST00000503079|ensembl:ENSP00000428128|ensembl:ENST00000506163|ensembl:ENSP00000424926|ensembl:ENST00000611442|ensembl:ENSP00000483768|ensembl:ENST00000614240|ensembl:ENSP00000479279|ensembl:ENSP00000479920|ensembl:ENST00000614773|ensembl:ENSP00000481427|ensembl:ENSP00000483515|ensembl:ENSP00000483819|ensembl:ENST00000622158|ensembl:ENSP00000480906|ensembl:ENSP00000482966|ensembl:ENST00000624634|ensembl:ENSP00000485595|ensembl:ENST00000626847|ensembl:ENSP00000486152|ensembl:ENSP00000487421|ensembl:ENST00000628353|ensembl:ENSP00000487029|ensembl:ENST00000628642|ensembl:ENSP00000487015|ensembl:ENSP00000487206|refseq:XP_016865275.1|dip:DIP-31309N|entrezgene/locuslink:6607(identity)	-	no-uniprot-update:	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:FFduCSFjK3s7VNWPyW67FjyPE7Y4932	rogid:QGivm7E8suciCWXO4l0zCUzCl2g9606	intact-crc:DB51950B9DC05F39|rigid:kJnLGc37hChO//AWrVZFL3x7IuY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q15427	intact:EBI-11522220	intact:EBI-348469|ensembl:ENSP00000271628|intact:EBI-1047735|uniprotkb:Q5SZ63	-	psi-mi:sf3b4_human(display_long)|uniprotkb:SF3B4(gene name)|psi-mi:SF3B4(display_short)|uniprotkb:SAP49(gene name synonym)|uniprotkb:Spliceosome-associated protein 49(gene name synonym)|uniprotkb:Pre-mRNA-splicing factor SF3b 49 kDa subunit(gene name synonym)	psi-mi:lsb3(display_short)|psi-mi:EBI-11522220(display_long)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11537918|imex:IM-24995-1632	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005841.1|ensembl:ENSG00000143368(gene)|ensembl:ENST00000271628(transcript)|rcsb pdb:6QX9|rcsb pdb:6Y53|rcsb pdb:6Y5Q|rcsb pdb:7ABG|rcsb pdb:7ABH|rcsb pdb:7ABI|rcsb pdb:7DVQ|reactome:R-HSA-72163|reactome:R-HSA-72165|rcsb pdb:6AHD|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:1990935"(splicing factor binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034158|go:"GO:0000375"(RNA splicing, via transesterification reactions)|interpro:IPR034159|interpro:IPR035979|mint:Q15427|rcsb pdb:1X5T|rcsb pdb:5GVQ|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|entrezgene/locuslink:10262(identity)	sgd:YFR024C-A(identity)	-	-	no-uniprot-update:	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Jgy6WmBFKkphpZLLte2GgsagUVI9606	rogid:lsGJZWImagMoiiCZztCcxCn2LlU4932	intact-crc:FEB8BA3BEDC61113|rigid:NuuZz3pXah3Iu9b4yqvrb3ZKfZE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:A0A6L1C4M5	uniprotkb:Q969F0	intact:EBI-11522494	intact:EBI-743099|ensembl:ENSP00000359375	psi-mi:a0a6l1c4m5_yeasx(display_long)|uniprotkb:PACBIOSEQ_LOCUS6219(orf name)|uniprotkb:PACBIOSEQ_LOCUS6225(orf name)|uniprotkb:PACBIOSEQ_LOCUS6235(orf name)|uniprotkb:PACBIOSEQ_LOCUS6264(orf name)|uniprotkb:PACBIOSEQ_LOCUS6286(orf name)|uniprotkb:PACBIOSEQ_LOCUS6327(orf name)|uniprotkb:SCNYR20_0005038000(orf name)|uniprotkb:SCP684_0005037600(orf name)	psi-mi:fate1_human(display_long)|uniprotkb:Tumor antigen BJ-HCC-2(gene name synonym)|uniprotkb:Cancer/testis antigen 43(gene name synonym)|uniprotkb:FATE1(gene name)|psi-mi:FATE1(display_short)|uniprotkb:FATE(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11538010|imex:IM-24995-1642	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016021"(integral component of membrane)|uniprotkb:A0A250WEI1(uniprot-removed-ac)|interpro:IPR019334|sgd:YPR153W(identity)	refseq:NP_149076.1|ensembl:ENSG00000147378(gene)|ensembl:ENST00000370350(transcript)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|go:"GO:0051562"(negative regulation of mitochondrial calcium ion concentration)|interpro:IPR039153|interpro:IPR039433|mint:Q969F0|entrezgene/locuslink:89885(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:SRq+kqkRupgoOO2oywFAv0D2VGc4932	rogid:Nm1N6lO92MHr5rIKC007oouF5RE9606	intact-crc:EEB22713C651169F|rigid:q8MR7lCVVaclXUxjJkQXOdptm2w	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
intact:EBI-11522220	uniprotkb:Q92841	-	intact:EBI-746012|uniprotkb:Q69YT1|uniprotkb:Q6ICD6|uniprotkb:H3BLZ8|uniprotkb:B1AHM0|ensembl:ENSP00000385536	psi-mi:lsb3(display_short)|psi-mi:EBI-11522220(display_long)	psi-mi:ddx17_human(display_long)|uniprotkb:DEAD box protein 17(gene name synonym)|uniprotkb:RNA-dependent helicase p72(gene name synonym)|uniprotkb:DEAD box protein p72(gene name synonym)|uniprotkb:DDX17(gene name)|psi-mi:DDX17(display_short)|uniprotkb:DEAD box protein p82(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11537999|imex:IM-24995-1641	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:YFR024C-A(identity)	refseq:NP_006377.2|ensembl:ENSG00000100201(gene)|ensembl:ENST00000403230(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006364"(rRNA processing)|go:"GO:0006396"(RNA processing)|go:"GO:0008186"(ATP-dependent activity, acting on RNA)|go:"GO:0010586"(miRNA metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0045445"(myoblast differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051607"(defense response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2001014"(regulation of skeletal muscle cell differentiation)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:Q92841|rcsb pdb:6UV0|rcsb pdb:6UV1|rcsb pdb:6UV2|rcsb pdb:6UV3|rcsb pdb:6UV4|reactome:R-HSA-3899300|dip:DIP-29843N|entrezgene/locuslink:10521(identity)	-	no-uniprot-update:	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:lsGJZWImagMoiiCZztCcxCn2LlU4932	rogid:3UhUuhRSZg/zlM7UPDKYCqNmUho9606	intact-crc:635BD3D2B05F4743|rigid:v6GkDh8mDkD5LIPm/bIWOwh+zZ0	false	-	sufficient binding region:80-729	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8NHQ1	intact:EBI-11522371	intact:EBI-739624|ensembl:ENSP00000264982|ensembl:ENSP00000419231|uniprotkb:Q96B31|uniprotkb:Q9H2C3|uniprotkb:Q9H2Z1|uniprotkb:Q9H940|uniprotkb:D3DNE9|uniprotkb:B7Z5I8|uniprotkb:B7Z7E8|uniprotkb:F5GZX8	-	psi-mi:cep70_human(display_long)|uniprotkb:CEP70(gene name)|psi-mi:CEP70(display_short)|uniprotkb:BITE(gene name synonym)|uniprotkb:p10-binding protein(gene name synonym)	psi-mi:yjr003c(display_short)|psi-mi:EBI-11522371(display_long)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11537990|imex:IM-24995-1640	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114107(gene)|ensembl:ENST00000264982(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|interpro:IPR019734|interpro:IPR037692|mint:Q8NHQ1|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|ensembl:ENST00000484888(transcript)|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_077817.2|refseq:XP_016862764.1|refseq:NP_001275893.1|refseq:NP_001275894.1|refseq:NP_001275895.1|refseq:NP_001275896.1|refseq:NP_001307527.1|refseq:NP_001307529.1|entrezgene/locuslink:80321(identity)	sgd:YJR003C(identity)	-	-	no-uniprot-update:	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:S4yveQWcvdVtAUX65gqrJ5Dv0Mc9606	rogid:dYGrrP3JnrXO2rj4v/nTT64la6A4932	intact-crc:6E4D95BF15F9EED1|rigid:jjEF/VSJJhKBsAhjrSDzZiMDUfo	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
intact:EBI-11522371	uniprotkb:Q8NEH6	-	intact:EBI-743811|uniprotkb:Q8IYT6|uniprotkb:Q9NUP4|ensembl:ENSP00000260453	psi-mi:yjr003c(display_short)|psi-mi:EBI-11522371(display_long)	psi-mi:mns1_human(display_long)|uniprotkb:MNS1(gene name)|psi-mi:MNS1(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11537981|imex:IM-24995-1639	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:YJR003C(identity)	refseq:NP_060835.1|ensembl:ENSG00000138587(gene)|ensembl:ENST00000260453(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005882"(intermediate filament)|go:"GO:0005930"(axoneme)|go:"GO:0007288"(sperm axoneme assembly)|go:"GO:0031514"(motile cilium)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042802"(identical protein binding)|go:"GO:0044782"(cilium organization)|go:"GO:0045724"(positive regulation of cilium assembly)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070986"(left/right axis specification)|interpro:IPR026504|interpro:IPR043597|mint:Q8NEH6|entrezgene/locuslink:55329(identity)	-	no-uniprot-update:	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:dYGrrP3JnrXO2rj4v/nTT64la6A4932	rogid:MRimzaWPUjIEXfbT3YufZtjt7Fk9606	intact-crc:FBC8B51433E7097A|rigid:+zu8ArXu8e08GzieRA9lcwUAg1U	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8N6Y0	intact:EBI-11522208	intact:EBI-739895|uniprotkb:Q8NBX7|uniprotkb:Q96KH3|uniprotkb:Q9BYI8|uniprotkb:A8K7L6|uniprotkb:B2RCR9|ensembl:ENSP00000252597	-	psi-mi:usbp1_human(display_long)|uniprotkb:USHBP1(gene name)|psi-mi:USHBP1(display_short)|uniprotkb:MCC-2(gene name synonym)|uniprotkb:AIE-75-binding protein(gene name synonym)|uniprotkb:AIEBP(gene name synonym)|uniprotkb:MCC2(gene name synonym)|uniprotkb:Mutated in colon cancer protein 2(gene name synonym)	psi-mi:ylr445w(display_short)|psi-mi:EBI-11522208(display_long)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11537972|imex:IM-24995-1638	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001284632.1|refseq:NP_114147.2|refseq:NP_001308346.1|ensembl:ENSG00000130307(gene)|ensembl:ENST00000252597(transcript)|go:"GO:0030165"(PDZ domain binding)|interpro:IPR019536|interpro:IPR040171|entrezgene/locuslink:83878(identity)	sgd:YLR445W(identity)	-	-	no-uniprot-update:	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:vY1qx73Ju/z7WDu6k1kd10ZDVRo9606	rogid:kUe7etYjGLH6i6KZ5N2LXUnjAf04932	intact-crc:643E15EED6C97BC3|rigid:ZdV5IG7C1GfGBnajMMlqxT7pdQc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q5TD97	intact:EBI-11522444	intact:EBI-750641|uniprotkb:Q5TD98|uniprotkb:Q8WW21|uniprotkb:Q9NQU2|uniprotkb:B2RBD1|uniprotkb:E1P526|ensembl:ENSP00000326022|ensembl:ENSP00000396390|ensembl:ENSP00000442357	-	psi-mi:fhl5_human(display_long)|uniprotkb:Activator of cAMP-responsive element modulator in testis(gene name synonym)|uniprotkb:FHL5(gene name)|psi-mi:FHL5(display_short)|uniprotkb:ACT(gene name synonym)	psi-mi:sen15(display_short)|psi-mi:EBI-11522444(display_long)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11537963|imex:IM-24995-1637	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164278.1|refseq:NP_065228.4|refseq:NP_001309395.1|refseq:NP_001309396.1|ensembl:ENSG00000112214(gene)|ensembl:ENST00000326771(transcript)|ensembl:ENST00000450218(transcript)|ensembl:ENST00000541107(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0030018"(Z disc)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR037987|interpro:IPR042947|mint:Q5TD97|rcsb pdb:1X68|entrezgene/locuslink:9457(identity)	sgd:YMR059W(identity)	-	-	no-uniprot-update:	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:AYHIHh+ibS4sNYAZY4ghojZOJOI9606	rogid:mmn7/rD7T68r+kJ8RV9USn4gnNI4932	intact-crc:C5AF982EC47BBD37|rigid:4Hg+guIIlsN0d0amItLmu80gYKc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
intact:EBI-11522552	uniprotkb:Q9C005	-	intact:EBI-744973|uniprotkb:D6W578|ensembl:ENSP00000295066|ensembl:ENSP00000345837	psi-mi:urh1(display_short)|psi-mi:EBI-11522552(display_long)	psi-mi:dpy30_human(display_long)|uniprotkb:DPY30(gene name)|psi-mi:DPY30(display_short)|uniprotkb:Dpy-30-like protein(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11538055|imex:IM-24995-1647	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:YDR400W(identity)	refseq:NP_115963.1|ensembl:ENSG00000162961(gene)|ensembl:ENST00000295066(transcript)|ensembl:ENST00000342166(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006348"|go:"GO:0016197"(endosomal transport)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|interpro:IPR007858(Dpy-30)|interpro:IPR037856|mint:Q9C005|rcsb pdb:3G36|rcsb pdb:4RIQ|rcsb pdb:4RT4|rcsb pdb:4RTA|rcsb pdb:6E2H|rcsb pdb:6PWV|reactome:R-HSA-3214841|reactome:R-HSA-8936459|refseq:NP_001308138.1|dip:DIP-34476N|entrezgene/locuslink:84661(identity)	-	no-uniprot-update:	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:uuys9fg/B71sAw+Tb2BvegAXdp84932	rogid:yC9NJhTfEIT+YyfWRSJLGbRsQkc9606	intact-crc:3C0CE181A31F5528|rigid:EL2T1hfc1Qz1xHaMPIuYHKHh9+c	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
intact:EBI-11522371	uniprotkb:Q96MT8-3	-	intact:EBI-11522539|ensembl:ENSP00000507703|ensembl:ENSP00000328382|ensembl:ENSP00000506728|ensembl:ENSP00000506791|ensembl:ENSP00000506828|ensembl:ENSP00000507228	psi-mi:yjr003c(display_short)|psi-mi:EBI-11522371(display_long)	psi-mi:q96mt8-3(display_long)|uniprotkb:CEP63(gene name)|psi-mi:CEP63(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11538046|imex:IM-24995-1646	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:YJR003C(identity)	intact:EBI-741977(isoform-parent)|ensembl:ENST00000332047(transcript)|ensembl:ENST00000682042(transcript)|ensembl:ENST00000682800(transcript)|ensembl:ENST00000682858(transcript)|ensembl:ENST00000683177(transcript)|ensembl:ENST00000683861(transcript)|ensembl:ENSG00000182923(gene)|uniprotkb:Q96MT8-3(isoform-parent)|entrezgene/locuslink:80254(identity)	-	no-uniprot-update:	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:dYGrrP3JnrXO2rj4v/nTT64la6A4932	rogid:U0uvVcOCzA8Qp2cCB0ilixgd4Yc9606	intact-crc:91571EBD82FAAAE3|rigid:vrpSQQZOtDJzpIaBlSp7W6As+vI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96IK5	intact:EBI-11522371	intact:EBI-2548508|ensembl:ENSP00000282570|uniprotkb:Q9H826|uniprotkb:Q9H8V7|uniprotkb:Q9H927	-	psi-mi:gmcl1_human(display_long)|uniprotkb:GMCL1(gene name)|psi-mi:GMCL1(display_short)|uniprotkb:GCL(gene name synonym)|uniprotkb:BTBD13(gene name synonym)|uniprotkb:SPATA29(gene name synonym)|uniprotkb:Spermatogenesis-associated protein 29(gene name synonym)	psi-mi:yjr003c(display_short)|psi-mi:EBI-11522371(display_long)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11538037|imex:IM-24995-1645	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000087338(gene)|ensembl:ENST00000282570(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0007281"(germ cell development)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016363"(nuclear matrix)|go:"GO:0042802"(identical protein binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR043380|refseq:NP_848526.1|entrezgene/locuslink:64395(identity)	sgd:YJR003C(identity)	-	-	no-uniprot-update:	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:ED8yqySVu7BWxpw3DUSNBZSQWrk9606	rogid:dYGrrP3JnrXO2rj4v/nTT64la6A4932	intact-crc:997CE4C72654A033|rigid:dbccop0gcphLz75QVz1aGzwaVvg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96BA8	intact:EBI-11522518	intact:EBI-6942903|ensembl:ENSP00000481956|intact:MINT-268046|intact:MINT-8162577|uniprotkb:Q8N2D5|uniprotkb:Q96CP0	-	psi-mi:cr3l1_human(display_long)|uniprotkb:CREB3L1(gene name)|psi-mi:CREB3L1(display_short)|uniprotkb:OASIS(gene name synonym)|uniprotkb:PSEC0238(orf name)|uniprotkb:Old astrocyte specifically-induced substance(gene name synonym)	psi-mi:ost2(display_short)|psi-mi:EBI-11522518(display_long)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11538028|imex:IM-24995-1644	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157613(gene)|ensembl:ENST00000621158(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0070278"(extracellular matrix constituent secretion)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029805|mint:Q96BA8|reactome:R-HSA-8874211|refseq:NP_443086.1|entrezgene/locuslink:90993(identity)	sgd:YOR103C(identity)	-	comment:mint|function:"Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE"	no-uniprot-update:	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:sMWUFmBeBBCO+T0Y2CuB/un1lBg9606	rogid:3gHEG/j4fiaHHY/qWGorqbRMBsg4932	intact-crc:025F13CF64B0FDD6|rigid:XEPVU11Ksmf99eDRO+Gztb1+AeY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q969F0	intact:EBI-11522506	intact:EBI-743099|ensembl:ENSP00000359375	-	psi-mi:fate1_human(display_long)|uniprotkb:Tumor antigen BJ-HCC-2(gene name synonym)|uniprotkb:Cancer/testis antigen 43(gene name synonym)|uniprotkb:FATE1(gene name)|psi-mi:FATE1(display_short)|uniprotkb:FATE(gene name synonym)	psi-mi:mps3(display_short)|psi-mi:EBI-11522506(display_long)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11538019|imex:IM-24995-1643	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_149076.1|ensembl:ENSG00000147378(gene)|ensembl:ENST00000370350(transcript)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|go:"GO:0051562"(negative regulation of mitochondrial calcium ion concentration)|interpro:IPR039153|interpro:IPR039433|mint:Q969F0|entrezgene/locuslink:89885(identity)	sgd:YJL019W(identity)	-	-	no-uniprot-update:	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Nm1N6lO92MHr5rIKC007oouF5RE9606	rogid:L0dsobyr9SpxA4nDPBr9V2OBaqU4932	intact-crc:1B1290AAFF103402|rigid:2wk6m3/qprPOZIJ4MLIY5UEXyU0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
intact:EBI-11522552	uniprotkb:Q9UGJ1-2	-	intact:EBI-10964469|ensembl:ENSP00000456648	psi-mi:urh1(display_short)|psi-mi:EBI-11522552(display_long)	psi-mi:q9ugj1-2(display_long)|uniprotkb:TUBGCP4(gene name)|psi-mi:TUBGCP4(display_short)|uniprotkb:76P(gene name synonym)|uniprotkb:GCP4(gene name synonym)|uniprotkb:Gamma-ring complex protein 76 kDa(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11538091|imex:IM-24995-1651	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:YDR400W(identity)	intact:EBI-1052544(isoform-parent)|ensembl:ENSG00000137822(gene)|ensembl:ENST00000564079(transcript)|uniprotkb:Q9UGJ1-2(isoform-parent)|entrezgene/locuslink:27229(identity)	-	no-uniprot-update:	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:uuys9fg/B71sAw+Tb2BvegAXdp84932	rogid:+lfeIRS3N2OU1+y84kUyKY7ePNA9606	intact-crc:C4CB1A28F8220334|rigid:00J1gknyAajcVLBEJSsfaooFtGE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
intact:EBI-11522208	uniprotkb:Q9NPJ6	-	intact:EBI-394607|uniprotkb:Q9BS95|uniprotkb:Q9NYR5|uniprotkb:Q53GB4|uniprotkb:Q53H68|uniprotkb:Q5T912|uniprotkb:Q6FHC4|uniprotkb:Q6IA79|uniprotkb:B4DX67|ensembl:ENSP00000258648	psi-mi:ylr445w(display_short)|psi-mi:EBI-11522208(display_long)	psi-mi:med4_human(display_long)|uniprotkb:HSPC126(orf name)|uniprotkb:DRIP36(gene name synonym)|uniprotkb:MED4(gene name)|psi-mi:MED4(display_short)|uniprotkb:ARC36(gene name synonym)|uniprotkb:Mediator complex subunit 4(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex 36 kDa component(gene name synonym)|uniprotkb:Activator-recruited cofactor 36 kDa component(gene name synonym)|uniprotkb:TRAP/SMCC/PC2 subunit p36 subunit(gene name synonym)|uniprotkb:VDRIP(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11538082|imex:IM-24995-1650	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:YLR445W(identity)	refseq:NP_001257558.1|refseq:NP_054885.1|ensembl:ENSG00000136146(gene)|ensembl:ENST00000258648(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0070847"(core mediator complex)|interpro:IPR019258|mint:Q9NPJ6|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|entrezgene/locuslink:29079(identity)	-	no-uniprot-update:	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:kUe7etYjGLH6i6KZ5N2LXUnjAf04932	rogid:Bept2Oec50gruA9e4pf+eEUiANM9606	intact-crc:8B6A1509D310C61C|rigid:5GC7wSGOu6bpZglvGPIeDsMqEms	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
intact:EBI-11522575	uniprotkb:Q9HD26-2	-	intact:EBI-11102276|ensembl:ENSP00000052569	psi-mi:mrpl15(display_short)|psi-mi:EBI-11522575(display_long)	psi-mi:q9hd26-2(display_long)|uniprotkb:GOPC(gene name)|psi-mi:GOPC(display_short)|uniprotkb:CAL(gene name synonym)|uniprotkb:CFTR-associated ligand(gene name synonym)|uniprotkb:FIG(gene name synonym)|uniprotkb:Fused in glioblastoma(gene name synonym)|uniprotkb:PDZ protein interacting specifically with TC10(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11538073|imex:IM-24995-1649	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:YLR312W-A(identity)	ensembl:ENSG00000047932(gene)|ensembl:ENST00000052569(transcript)|intact:EBI-349832(isoform-parent)|uniprotkb:Q9HD26-2(isoform-parent)|entrezgene/locuslink:57120(identity)	-	no-uniprot-update:	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:ZU12R+PdYknw8Q1ARUw5V55WN/84932	rogid:QoEGY54FfmwTrpGVMQN9ASGPgVI9606	intact-crc:4C877D92618C9954|rigid:vQuqXIXBBj18kH4Ysh8GtSN2BtU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9H9H4	intact:EBI-11522220	intact:EBI-4400866|intact:EBI-28975719|ensembl:ENSP00000267202	-	psi-mi:vp37b_human(display_long)|uniprotkb:VPS37B(gene name)|psi-mi:VPS37B(display_short)|uniprotkb:ESCRT-I complex subunit VPS37B(gene name synonym)	psi-mi:lsb3(display_short)|psi-mi:EBI-11522220(display_long)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11538064|imex:IM-24995-1648	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000267202|refseq:NP_078943.1|ensembl:ENSG00000139722(gene)|ensembl:ENST00000267202(transcript)|go:"GO:0000813"(ESCRT I complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0010008"(endosome membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0030496"(midbody)|go:"GO:0031902"(late endosome membrane)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1902188"(obsolete positive regulation of viral release from host cell)|go:"GO:1903774"(positive regulation of viral budding via host ESCRT complex)|interpro:IPR009851(Modifier of rudimentary, Modr)|interpro:IPR029012|interpro:IPR037202|mint:Q9H9H4|rcsb pdb:6VME|reactome:R-HSA-162588|reactome:R-HSA-174490|reactome:R-HSA-917729|reactome:R-HSA-9610379|reactome:R-HSA-9615710|entrezgene/locuslink:79720(identity)	sgd:YFR024C-A(identity)	-	-	no-uniprot-update:	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:dj398+zsegXf+gk9OiSeZAVlmqk9606	rogid:lsGJZWImagMoiiCZztCcxCn2LlU4932	intact-crc:2C29CF6BBEAF5FA7|rigid:UNiURDIqj4ktekX/LN3iVCNQy6o	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UMX0	uniprotkb:A0A6A5PVQ3	intact:EBI-741480|uniprotkb:Q8IXS9|uniprotkb:Q8N2Q3|uniprotkb:Q9H0T8|uniprotkb:Q9H3R4|uniprotkb:Q9HAZ5|intact:EBI-28967608|ensembl:ENSP00000365576|uniprotkb:Q5T6J5|uniprotkb:Q5T6J9|uniprotkb:A0A024R284	intact:EBI-11522614	psi-mi:ubql1_human(display_long)|uniprotkb:Protein linking IAP with cytoskeleton 1(gene name synonym)|uniprotkb:UBQLN1(gene name)|psi-mi:UBQLN1(display_short)|uniprotkb:DA41(gene name synonym)|uniprotkb:PLIC1(gene name synonym)	psi-mi:a0a6a5pvq3_yeasx(display_long)|uniprotkb:PACBIOSEQ_LOCUS3560(orf name)|uniprotkb:PACBIOSEQ_LOCUS3564(orf name)|uniprotkb:PACBIOSEQ_LOCUS3592(orf name)|uniprotkb:PACBIOSEQ_LOCUS3594(orf name)|uniprotkb:PACBIOSEQ_LOCUS3635(orf name)|uniprotkb:SCNYR20_0010010900(orf name)|uniprotkb:SCP684_0010010800(orf name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11538111|imex:IM-24995-1653	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000257468|ensembl:ENSP00000257468|ensembl:ENSP00000365576|ensembl:ENSG00000135018(gene)|ensembl:ENST00000376395(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000502"(proteasome complex)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016235"(aggresome)|go:"GO:0016236"(macroautophagy)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0019900"(kinase binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035973"(aggrephagy)|go:"GO:0042802"(identical protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0097352"(autophagosome maturation)|go:"GO:1901340"(negative regulation of store-operated calcium channel activity)|go:"GO:1902175"(regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)|interpro:IPR000626(Ubiquitin)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR028430|interpro:IPR029071|mint:Q9UMX0|rcsb pdb:2JY5|rcsb pdb:2JY6|rcsb pdb:2KLC|reactome:R-HSA-8856825|refseq:NP_038466.2|refseq:NP_444295.1|dip:DIP-41629N|entrezgene/locuslink:29979(identity)	interpro:IPR000420(Yeast PIR protein repeat)|go:"GO:0005199"(structural constituent of cell wall)|go:"GO:0005618"(cell wall)|uniprotkb:A0A250WIX2(uniprot-removed-ac)|sgd:YKL096W-A(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:nCFfZbGCTvRYaXhQ4R99XblslvM9606	rogid:I1pf6N/8dUODvb5jhcXC902uuew4932	intact-crc:D57379C5432A9FF3|rigid:+8QzAI8pX+olAfWRefZI12z170I	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UJX2	intact:EBI-11522371	intact:EBI-396137|uniprotkb:O75433|uniprotkb:Q9BS73|uniprotkb:B4E3A2|uniprotkb:B7WP05|uniprotkb:Q53FN2|uniprotkb:A8K6E5|uniprotkb:D3DQB7|ensembl:ENSP00000378350	-	psi-mi:cdc23_human(display_long)|uniprotkb:CDC23(gene name)|psi-mi:CDC23(display_short)|uniprotkb:ANAPC8(gene name synonym)|uniprotkb:Anaphase-promoting complex subunit 8(gene name synonym)|uniprotkb:Cyclosome subunit 8(gene name synonym)	psi-mi:yjr003c(display_short)|psi-mi:EBI-11522371(display_long)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11538100|imex:IM-24995-1652	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004652.2|dip:DIP-32959N|ensembl:ENSG00000094880(gene)|ensembl:ENST00000394886(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0007091"(metaphase/anaphase transition of mitotic cell cycle)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030071"(regulation of mitotic metaphase/anaphase transition)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0051301"(cell division)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR007192(Cdc23)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|mint:Q9UJX2|rcsb pdb:4UI9|rcsb pdb:5A31|rcsb pdb:5G04|rcsb pdb:5G05|rcsb pdb:5KHR|rcsb pdb:5KHU|rcsb pdb:5L9T|rcsb pdb:5L9U|rcsb pdb:5LCW|rcsb pdb:6Q6G|rcsb pdb:6Q6H|rcsb pdb:6TLJ|rcsb pdb:6TM5|rcsb pdb:6TNT|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-9687136|reactome:R-HSA-983168|entrezgene/locuslink:8697(identity)	sgd:YJR003C(identity)	-	-	no-uniprot-update:	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:uTZL2UHzZHLoKnio/1LcuSzZpW09606	rogid:dYGrrP3JnrXO2rj4v/nTT64la6A4932	intact-crc:A4BC13A8D98C7792|rigid:PDeq10RYhZ+fN+OuxIR+rI3fZWw	false	sufficient binding region:7-597	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P43365	uniprotkb:O13539	intact:EBI-749530|uniprotkb:Q9NSD3|intact:EBI-10178394|uniprotkb:Q6FHH8|ensembl:ENSP00000350592|ensembl:ENSP00000377447|ensembl:ENSP00000377478	intact:EBI-30898|uniprotkb:D3DLB6|ensemblfungi:YHR167W	psi-mi:magac_human(display_long)|uniprotkb:MAGE-12 antigen(gene name synonym)|uniprotkb:MAGE12F antigen(gene name synonym)|uniprotkb:Cancer/testis antigen 1.12(gene name synonym)|uniprotkb:MAGEA12(gene name)|psi-mi:MAGEA12(display_short)|uniprotkb:MAGE12(gene name synonym)	psi-mi:thp2_yeast(display_long)|uniprotkb:THP2(gene name)|psi-mi:THP2(display_short)|uniprotkb:YHR167W(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11538149|imex:IM-24995-1657	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001159858.1|refseq:NP_001159859.1|refseq:NP_005358.2|ensembl:ENSG00000213401(gene)|ensembl:ENST00000357916(transcript)|ensembl:ENST00000393869(transcript)|ensembl:ENST00000393900(transcript)|interpro:IPR002190(MAGE protein)|interpro:IPR021072|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|entrezgene/locuslink:4111(identity)	refseq:NP_012037.1|sgd:S000001210|dip:DIP-4246N|mint:O13539|ensemblfungi:YHR167W(gene)|ensemblfungi:YHR167W_mRNA(transcript)|go:"GO:0000445"(THO complex part of transcription export complex)|go:"GO:0000446"(nucleoplasmic THO complex)|go:"GO:0000723"(telomere maintenance)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0006310"(DNA recombination)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0034063"(stress granule assembly)|interpro:IPR018557|rcsb pdb:7APX|rcsb pdb:7LUV|sgd:YHR167W(identity)	-	-	crc64:16EFA6F464507C57	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:3/Jxz2VsFOb67RWqWj3xbTrw3s49606	rogid:SaTSL6jLwX1hTVCqvU8ZNR96r8U559292	intact-crc:F388C4D09A5E07E8|rigid:Jen9lZoSJESpiOwO7zbT6YrU1sw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O13539	uniprotkb:O14964	intact:EBI-30898|uniprotkb:D3DLB6|ensemblfungi:YHR167W	intact:EBI-740220|uniprotkb:Q9NR36|ensembl:ENSP00000331201|ensembl:ENSP00000504106	psi-mi:thp2_yeast(display_long)|uniprotkb:THP2(gene name)|psi-mi:THP2(display_short)|uniprotkb:YHR167W(locus name)	psi-mi:hgs_human(display_long)|uniprotkb:Protein pp110(gene name synonym)|uniprotkb:Hrs(gene name synonym)|uniprotkb:HGS(gene name)|psi-mi:HGS(display_short)|uniprotkb:HRS(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11538140|imex:IM-24995-1656	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012037.1|sgd:S000001210|dip:DIP-4246N|mint:O13539|ensemblfungi:YHR167W(gene)|ensemblfungi:YHR167W_mRNA(transcript)|go:"GO:0000445"(THO complex part of transcription export complex)|go:"GO:0000446"(nucleoplasmic THO complex)|go:"GO:0000723"(telomere maintenance)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0006310"(DNA recombination)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0034063"(stress granule assembly)|interpro:IPR018557|rcsb pdb:7APX|rcsb pdb:7LUV|sgd:YHR167W(identity)	refseq:NP_004703.1|dip:DIP-29050N|ensembl:ENSG00000185359(gene)|ensembl:ENST00000329138(transcript)|ensembl:ENST00000676546(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0007165"(signal transduction)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010324"(membrane invagination)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010642"(negative regulation of platelet-derived growth factor receptor signaling pathway)|go:"GO:0016197"(endosomal transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032585"(multivesicular body membrane)|go:"GO:0033565"(ESCRT-0 complex)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043405"(regulation of MAP kinase activity)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072657"(protein localization to membrane)|go:"GO:0097013"(phagocytic vesicle lumen)|go:"GO:1903543"(positive regulation of exosomal secretion)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR002014(VHS)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017073(Ubiquitin binding protein, Hrs/VPS27)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR024641|mint:O14964|rcsb pdb:2D3G|rcsb pdb:3F1I|rcsb pdb:3OBQ|rcsb pdb:3ZYQ|rcsb pdb:4AVX|reactome:R-HSA-182971|reactome:R-HSA-432720|reactome:R-HSA-5689880|reactome:R-HSA-6807004|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8875360|reactome:R-HSA-9013420|reactome:R-HSA-917729|reactome:R-HSA-9635644|reactome:R-HSA-9636383|reactome:R-HSA-9706019|entrezgene/locuslink:9146(identity)	-	crc64:16EFA6F464507C57	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:SaTSL6jLwX1hTVCqvU8ZNR96r8U559292	rogid:z/AnREuqEpyJ9/Zj6JFCJCJem1I9606	intact-crc:FA9764A91A5EFA9E|rigid:UC+FrYLu9HP0ocapfmrftA9xbGU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q7Z6G3-2	uniprotkb:O13539	intact:EBI-10172876|ensembl:ENSP00000457354|intact:EBI-14062040	intact:EBI-30898|uniprotkb:D3DLB6|ensemblfungi:YHR167W	psi-mi:q7z6g3-2(display_long)|uniprotkb:EFCBP2(gene name synonym)|uniprotkb:Neuronal calcium-binding protein 2(gene name synonym)|uniprotkb:Synaptotagmin-interacting protein 2(gene name synonym)|uniprotkb:NECAB2(gene name)|psi-mi:NECAB2(display_short)	psi-mi:thp2_yeast(display_long)|uniprotkb:THP2(gene name)|psi-mi:THP2(display_short)|uniprotkb:YHR167W(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11538129|imex:IM-24995-1655	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000103154(gene)|ensembl:ENST00000565691(transcript)|uniprotkb:Q7Z6G3-2(isoform-parent)|intact:EBI-950070(isoform-parent)|entrezgene/locuslink:54550(identity)	refseq:NP_012037.1|sgd:S000001210|dip:DIP-4246N|mint:O13539|ensemblfungi:YHR167W(gene)|ensemblfungi:YHR167W_mRNA(transcript)|go:"GO:0000445"(THO complex part of transcription export complex)|go:"GO:0000446"(nucleoplasmic THO complex)|go:"GO:0000723"(telomere maintenance)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0006310"(DNA recombination)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0034063"(stress granule assembly)|interpro:IPR018557|rcsb pdb:7APX|rcsb pdb:7LUV|sgd:YHR167W(identity)	-	-	crc64:16EFA6F464507C57	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:4S7oIx6h+mKzV3EPxqcfMNqaNko9606	rogid:SaTSL6jLwX1hTVCqvU8ZNR96r8U559292	intact-crc:456B2D3EF3C1B42A|rigid:V2uDZVRRDFQLR0A82FXu/kkIes8	false	sufficient binding region:65-303	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
intact:EBI-11522626	uniprotkb:Q9UMX0	-	intact:EBI-741480|uniprotkb:Q8IXS9|uniprotkb:Q8N2Q3|uniprotkb:Q9H0T8|uniprotkb:Q9H3R4|uniprotkb:Q9HAZ5|intact:EBI-28967608|ensembl:ENSP00000365576|uniprotkb:Q5T6J5|uniprotkb:Q5T6J9|uniprotkb:A0A024R284	psi-mi:a0a6a5q521_yeasx(display_short)|psi-mi:EBI-11522626(display_long)|uniprotkb:PACBIOSEQ_LOCUS284(orf name)	psi-mi:ubql1_human(display_long)|uniprotkb:Protein linking IAP with cytoskeleton 1(gene name synonym)|uniprotkb:UBQLN1(gene name)|psi-mi:UBQLN1(display_short)|uniprotkb:DA41(gene name synonym)|uniprotkb:PLIC1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11538120|imex:IM-24995-1654	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:A0A6A5Q521(uniprot-removed-ac)|sgd:YBR067C(identity)	ensembl:ENST00000257468|ensembl:ENSP00000257468|ensembl:ENSP00000365576|ensembl:ENSG00000135018(gene)|ensembl:ENST00000376395(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000502"(proteasome complex)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016235"(aggresome)|go:"GO:0016236"(macroautophagy)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0019900"(kinase binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035973"(aggrephagy)|go:"GO:0042802"(identical protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0097352"(autophagosome maturation)|go:"GO:1901340"(negative regulation of store-operated calcium channel activity)|go:"GO:1902175"(regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)|interpro:IPR000626(Ubiquitin)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR028430|interpro:IPR029071|mint:Q9UMX0|rcsb pdb:2JY5|rcsb pdb:2JY6|rcsb pdb:2KLC|reactome:R-HSA-8856825|refseq:NP_038466.2|refseq:NP_444295.1|dip:DIP-41629N|entrezgene/locuslink:29979(identity)	-	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:FaEZGfVcEXllbT1sM1VpEOeuSZ44932	rogid:nCFfZbGCTvRYaXhQ4R99XblslvM9606	intact-crc:B909A2B24CAB6805|rigid:Tg01hQ8vVfdjzmV3F2fkNjQw2B4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P00330	uniprotkb:Q15645	intact:EBI-2218|uniprotkb:D6W1Y3|ensemblfungi:YOL086C	intact:EBI-358993|uniprotkb:C9K0T3|uniprotkb:O15324|ensembl:ENSP00000166345|uniprotkb:D3DTC0	psi-mi:adh1_yeast(display_long)|uniprotkb:ADH1(gene name)|psi-mi:ADH1(display_short)|uniprotkb:ADC1(gene name synonym)|uniprotkb:YOL086C(locus name)|uniprotkb:O0947(orf name)|uniprotkb:Alcohol dehydrogenase I(gene name synonym)|uniprotkb:YADH-1(gene name synonym)	psi-mi:pch2_human(display_long)|uniprotkb:TRIP13(gene name)|psi-mi:TRIP13(display_short)|uniprotkb:Thyroid receptor-interacting protein 13(gene name synonym)|uniprotkb:PCH2(gene name synonym)|uniprotkb:Thyroid hormone receptor interactor 13(gene name synonym)|uniprotkb:Human papillomavirus type 16 E1 protein-binding protein(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11538221|imex:IM-24995-1665	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014555.1|sgd:S000005446|dip:DIP-1143N|mint:P00330|ensemblfungi:YOL086C(gene)|ensemblfungi:YOL086C_mRNA(transcript)|go:"GO:0000947"(amino acid catabolic process to alcohol via Ehrlich pathway)|go:"GO:0004022"("alcohol dehydrogenase (NAD+) activity")|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006116"(NADH oxidation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019170"("methylglyoxal reductase (NADH-dependent) activity")|go:"GO:0042802"(identical protein binding)|go:"GO:0043458"(ethanol biosynthetic process involved in glucose fermentation to ethanol)|go:"GO:0045069"(regulation of viral genome replication)|go:"GO:0046809"(replication compartment)|go:"GO:1904408"(melatonin binding)|interpro:IPR002328(Alcohol dehydrogenase, zinc-containing, conserved site)|interpro:IPR011032(GroES-like)|interpro:IPR013149(Alcohol dehydrogenase, zinc-binding)|interpro:IPR013154(Alcohol dehydrogenase GroES-like)|interpro:IPR020843|interpro:IPR036291|rcsb pdb:4W6Z|rcsb pdb:5ENV|sgd:YOL086C(identity)	refseq:NP_004228.1|ensembl:ENSG00000071539(gene)|ensembl:ENST00000166345(transcript)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|refseq:XP_011512465.1|dip:DIP-34493N|go:"GO:0005694"(chromosome)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0007141"(male meiosis I)|go:"GO:0007144"(female meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007286"(spermatid development)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051598"(meiotic recombination checkpoint signaling)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR027417|interpro:IPR044539|mint:Q15645|rcsb pdb:5VQ9|rcsb pdb:5VQA|rcsb pdb:5WC2|rcsb pdb:6F0X|rcsb pdb:6LK0|rcsb pdb:7L9P|entrezgene/locuslink:9319(identity)	-	crc64:F14AE24B5D8D12A5	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:ud0TIPDwB9vm9Ug9a5a4wY20oZ8559292	rogid:heF2f3R2lGIpZ80mZHnhMktXTE49606	intact-crc:B19CB5E8914CA570|rigid:84bDhYeVJEiw569dEKt/iNyltFs	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O14468	uniprotkb:Q9P2A4	intact:EBI-2343965|uniprotkb:D6W304|ensemblfungi:YOR304C-A	intact:EBI-742038|uniprotkb:C9IZN8|ensembl:ENSP00000225941|uniprotkb:Q9H0P6	psi-mi:yo304_yeast(display_long)|uniprotkb:YOR304C-A(locus name)	psi-mi:abi3_human(display_long)|uniprotkb:New molecule including SH3(gene name synonym)|uniprotkb:ABI3(gene name)|psi-mi:ABI3(display_short)|uniprotkb:NESH(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11538212|imex:IM-24995-1664	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005830|refseq:NP_014949.3|mint:O14468|ensemblfungi:YOR304C-A(gene)|ensemblfungi:YOR304C-A_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005933"(cellular bud)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0043332"(mating projection tip)|go:"GO:0051017"(actin filament bundle assembly)|sgd:YOR304C-A(identity)	refseq:NP_001128658.1|refseq:NP_057512.1|ensembl:ENSG00000108798(gene)|ensembl:ENST00000225941(transcript)|go:"GO:0002357"(defense response to tumor cell)|go:"GO:0005737"(cytoplasm)|go:"GO:0010593"(negative regulation of lamellipodium assembly)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031209"(SCAR complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0051015"(actin filament binding)|go:"GO:0061001"(regulation of dendritic spine morphogenesis)|go:"GO:0099151"(regulation of postsynaptic density assembly)|go:"GO:1900028"(negative regulation of ruffle assembly)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|go:"GO:2000249"(regulation of actin cytoskeleton reorganization)|go:"GO:2000774"(positive regulation of cellular senescence)|interpro:IPR001452(Src homology-3)|interpro:IPR012849(Abl-interactor, homeo-domain homologous region)|interpro:IPR028455|interpro:IPR028457|interpro:IPR036028|mint:Q9P2A4|entrezgene/locuslink:51225(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:+5KU/P9FeqlhSbGhpYJ1V6DqQNg559292	rogid:VAjz40ulLa5L+GmfL7ia5wTDND49606	intact-crc:C0FB902E3A2C3012|rigid:SQBbXoZnK7LCw4iWRo2H61tTfMM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9BYV6-2	uniprotkb:O14468	intact:EBI-11522718|ensembl:ENSP00000297348	intact:EBI-2343965|uniprotkb:D6W304|ensemblfungi:YOR304C-A	psi-mi:q9byv6-2(display_long)|uniprotkb:TRIM55(gene name)|psi-mi:TRIM55(display_short)|uniprotkb:MURF2(gene name synonym)|uniprotkb:Muscle-specific RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 29(gene name synonym)|uniprotkb:RNF29(gene name synonym)|uniprotkb:p50(isoform synonym)	psi-mi:yo304_yeast(display_long)|uniprotkb:YOR304C-A(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11538203|imex:IM-24995-1663	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-2341179(isoform-parent)|uniprotkb:Q9BYV6-2(isoform-parent)|ensembl:ENSG00000147573(gene)|ensembl:ENST00000353317(transcript)|entrezgene/locuslink:84675(identity)	sgd:S000005830|refseq:NP_014949.3|mint:O14468|ensemblfungi:YOR304C-A(gene)|ensemblfungi:YOR304C-A_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005933"(cellular bud)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0043332"(mating projection tip)|go:"GO:0051017"(actin filament bundle assembly)|sgd:YOR304C-A(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:9t8UhK+Z1yBqjnQrOqPD76NuXGg9606	rogid:+5KU/P9FeqlhSbGhpYJ1V6DqQNg559292	intact-crc:888EACF5A1262466|rigid:psr/fBzv8+d0CL4Ih+FUBQXeXww	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96HT8	uniprotkb:O14468	intact:EBI-748896|uniprotkb:Q6NXT8|uniprotkb:Q9P0J5|uniprotkb:B2R6R0|ensembl:ENSP00000318154	intact:EBI-2343965|uniprotkb:D6W304|ensemblfungi:YOR304C-A	psi-mi:mr1l1_human(display_long)|uniprotkb:PP784(orf name)|uniprotkb:MRFAP1L1(gene name)|psi-mi:MRFAP1L1(display_short)	psi-mi:yo304_yeast(display_long)|uniprotkb:YOR304C-A(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11538194|imex:IM-24995-1662	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_982287.1|refseq:XP_005247989.1|ensembl:ENSG00000178988(gene)|ensembl:ENST00000320848(transcript)|go:"GO:0042802"(identical protein binding)|interpro:IPR029254|mint:Q96HT8|dip:DIP-29019N|entrezgene/locuslink:114932(identity)	sgd:S000005830|refseq:NP_014949.3|mint:O14468|ensemblfungi:YOR304C-A(gene)|ensemblfungi:YOR304C-A_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005933"(cellular bud)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0043332"(mating projection tip)|go:"GO:0051017"(actin filament bundle assembly)|sgd:YOR304C-A(identity)	-	caution:This sequence has been withdrawn from Uniprot.|crc64:6C914B0B4BEECAE5	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:hb4enqSS7DeieOByDoLDkXkSlIk9606	rogid:+5KU/P9FeqlhSbGhpYJ1V6DqQNg559292	intact-crc:51D7EB457B63CB97|rigid:vkfqnxFf5tR9GxUo1dAyIRUfIB0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O14468	uniprotkb:Q8TC20-4	intact:EBI-2343965|uniprotkb:D6W304|ensemblfungi:YOR304C-A	intact:EBI-11522698|ensembl:ENSP00000390644	psi-mi:yo304_yeast(display_long)|uniprotkb:YOR304C-A(locus name)	psi-mi:q8tc20-4(display_long)|uniprotkb:CTAG3(gene name synonym)|uniprotkb:Cancer/testis antigen 3(gene name synonym)|uniprotkb:CAGE1(gene name)|psi-mi:CAGE1(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11538185|imex:IM-24995-1661	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005830|refseq:NP_014949.3|mint:O14468|ensemblfungi:YOR304C-A(gene)|ensemblfungi:YOR304C-A_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005933"(cellular bud)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0043332"(mating projection tip)|go:"GO:0051017"(actin filament bundle assembly)|sgd:YOR304C-A(identity)	intact:EBI-10196469(isoform-parent)|ensembl:ENSG00000164304(gene)|ensembl:ENST00000458291(transcript)|uniprotkb:Q8TC20-4(isoform-parent)|entrezgene/locuslink:285782(identity)	-	-	isoform-comment:No experimental confirmation available. May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:+5KU/P9FeqlhSbGhpYJ1V6DqQNg559292	rogid:rbycl1bawuMuBA8D5NfrekzCADM9606	intact-crc:73A2908DAD0739BE|rigid:m8EFDhKq0op7IB8ISGsuBL8uk4s	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O13566	uniprotkb:O14964	intact:EBI-29708|ensemblfungi:YPR123C	intact:EBI-740220|uniprotkb:Q9NR36|ensembl:ENSP00000331201|ensembl:ENSP00000504106	psi-mi:yp123_yeast(display_long)|uniprotkb:P9642.4B(orf name)|uniprotkb:YPR123C(locus name)	psi-mi:hgs_human(display_long)|uniprotkb:Protein pp110(gene name synonym)|uniprotkb:Hrs(gene name synonym)|uniprotkb:HGS(gene name)|psi-mi:HGS(display_short)|uniprotkb:HRS(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11538176|imex:IM-24995-1660	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000006327|dip:DIP-3811N|ensemblfungi:YPR123C(gene)|ensemblfungi:YPR123C_mRNA(transcript)|go:"GO:0016021"(integral component of membrane)|sgd:YPR123C(identity)	refseq:NP_004703.1|dip:DIP-29050N|ensembl:ENSG00000185359(gene)|ensembl:ENST00000329138(transcript)|ensembl:ENST00000676546(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0007165"(signal transduction)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010324"(membrane invagination)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010642"(negative regulation of platelet-derived growth factor receptor signaling pathway)|go:"GO:0016197"(endosomal transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032585"(multivesicular body membrane)|go:"GO:0033565"(ESCRT-0 complex)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043405"(regulation of MAP kinase activity)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072657"(protein localization to membrane)|go:"GO:0097013"(phagocytic vesicle lumen)|go:"GO:1903543"(positive regulation of exosomal secretion)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR002014(VHS)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017073(Ubiquitin binding protein, Hrs/VPS27)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR024641|mint:O14964|rcsb pdb:2D3G|rcsb pdb:3F1I|rcsb pdb:3OBQ|rcsb pdb:3ZYQ|rcsb pdb:4AVX|reactome:R-HSA-182971|reactome:R-HSA-432720|reactome:R-HSA-5689880|reactome:R-HSA-6807004|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8875360|reactome:R-HSA-9013420|reactome:R-HSA-917729|reactome:R-HSA-9635644|reactome:R-HSA-9636383|reactome:R-HSA-9706019|entrezgene/locuslink:9146(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:tb84y2TgUcLXIj6zwqC/7T8QHKg559292	rogid:z/AnREuqEpyJ9/Zj6JFCJCJem1I9606	intact-crc:63CC93691CF5FD61|rigid:Rl06iksuRyNqdidnPspyEoRr7kI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96ED9-2	uniprotkb:O13541	intact:EBI-10961706|ensembl:ENSP00000264827	intact:EBI-11522678|ensemblfungi:YLR280C	psi-mi:q96ed9-2(display_long)|uniprotkb:HOOK2(gene name)|psi-mi:HOOK2(display_short)	psi-mi:yl280_yeast(display_long)|uniprotkb:YLR280C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11538167|imex:IM-24995-1659	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000095066(gene)|ensembl:ENST00000264827(transcript)|intact:EBI-743290(isoform-parent)|uniprotkb:Q96ED9-2(isoform-parent)|entrezgene/locuslink:29911(identity)	ensemblfungi:YLR280C(gene)|ensemblfungi:YLR280C_mRNA(transcript)|sgd:S000004270|sgd:YLR280C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/03/16	rogid:aJZ/iDJpRk5dFL1NiouLuTjnOnc9606	rogid:tBIn1i72eUTn5Ht00WY4yxkAAFU559292	intact-crc:832B0BD835DC4F4B|rigid:Zg6EYZUtXKY0+thghDqrLPJuSnw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O13539	uniprotkb:Q15834	intact:EBI-30898|uniprotkb:D3DLB6|ensemblfungi:YHR167W	intact:EBI-739674|uniprotkb:Q96HA0|uniprotkb:B2R598|ensembl:ENSP00000311695	psi-mi:thp2_yeast(display_long)|uniprotkb:THP2(gene name)|psi-mi:THP2(display_short)|uniprotkb:YHR167W(locus name)	psi-mi:cc85b_human(display_long)|uniprotkb:CCDC85B(gene name)|psi-mi:CCDC85B(display_short)|uniprotkb:Hepatitis delta antigen-interacting protein A(gene name synonym)|uniprotkb:DIPA(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11538158|imex:IM-24995-1658	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012037.1|sgd:S000001210|dip:DIP-4246N|mint:O13539|ensemblfungi:YHR167W(gene)|ensemblfungi:YHR167W_mRNA(transcript)|go:"GO:0000445"(THO complex part of transcription export complex)|go:"GO:0000446"(nucleoplasmic THO complex)|go:"GO:0000723"(telomere maintenance)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0006310"(DNA recombination)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0034063"(stress granule assembly)|interpro:IPR018557|rcsb pdb:7APX|rcsb pdb:7LUV|sgd:YHR167W(identity)	refseq:NP_006839.2|ensembl:ENSG00000175602(gene)|ensembl:ENST00000312579(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005912"(adherens junction)|go:"GO:0030154"(cell differentiation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0070097"(delta-catenin binding)|interpro:IPR019359|entrezgene/locuslink:11007(identity)	-	crc64:16EFA6F464507C57	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:SaTSL6jLwX1hTVCqvU8ZNR96r8U559292	rogid:DUMY8gDRLRjC4Iu+z7SVBZ6sQkY9606	intact-crc:E04BA24CB3784884|rigid:P/TDjEqBpyXpQmTQQPkNo6/Nytc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P01097	uniprotkb:Q8IUQ4-2	intact:EBI-8874|ensemblfungi:YDL181W|uniprotkb:D6VRH1	intact:EBI-11522811|ensembl:ENSP00000349156	psi-mi:atif_yeast(display_long)|uniprotkb:INH1(gene name)|psi-mi:INH1(display_short)|uniprotkb:ATP synthase F1 subunit epsilon(gene name synonym)|uniprotkb:D1305(orf name)|uniprotkb:YDL181W(locus name)	psi-mi:q8iuq4-2(display_long)|uniprotkb:SIAH1(gene name)|psi-mi:SIAH1(display_short)|uniprotkb:HUMSIAH(gene name synonym)|uniprotkb:Seven in absentia homolog 1(gene name synonym)|uniprotkb:Siah-1a(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase SIAH1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11538284|imex:IM-24995-1672	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YDL181W(gene)|ensemblfungi:YDL181W_mRNA(transcript)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0042030"(ATPase inhibitor activity)|interpro:IPR007648(Mitochondrial ATPase inhibitor, IATP)|rcsb pdb:3ZIA|refseq:NP_010100.1|sgd:S000002340|mint:P01097|dip:DIP-2985N|sgd:YDL181W(identity)	intact:EBI-747107(isoform-parent)|ensembl:ENSG00000196470(gene)|ensembl:ENST00000356721(transcript)|uniprotkb:Q8IUQ4-2(isoform-parent)|entrezgene/locuslink:6477(identity)	-	crc64:E1AF73A47F63CE58	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:3wsu4TOLAZdm97Kfhla8l4UKFEk559292	rogid:M4q06jVbWuq1mGMXvtuFBaMEgZM9606	intact-crc:452D9E3131AF38B8|rigid:lxgj5yAVRLdMImSQ2jj9qkoEhcI	false	-	sufficient binding region:32-313	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O43765	uniprotkb:P00724	intact:EBI-347996|ensembl:ENSP00000221566|ensembl:ENSP00000503397|ensembl:ENSP00000504495|uniprotkb:Q9BTZ9|intact:EBI-1045243|uniprotkb:Q6FIA9|uniprotkb:D6W610	intact:EBI-9282|ensemblfungi:YIL162W|uniprotkb:Q12671|uniprotkb:D6VVC4	psi-mi:sgta_human(display_long)|uniprotkb:SGTA(gene name)|psi-mi:SGTA(display_short)|uniprotkb:SGT(gene name synonym)|uniprotkb:Alpha-SGT(gene name synonym)|uniprotkb:Vpu-binding protein(gene name synonym)|uniprotkb:SGT1(gene name synonym)	psi-mi:inv2_yeast(display_long)|uniprotkb:SUC2(gene name)|psi-mi:SUC2(display_short)|uniprotkb:YIL162W(locus name)|uniprotkb:Beta-fructofuranosidase 2(gene name synonym)|uniprotkb:Saccharase(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11538275|imex:IM-24995-1671	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:4CPG|rcsb pdb:4GOD|rcsb pdb:4GOE|rcsb pdb:4GOF|reactome:R-HSA-9609523|rcsb pdb:2VYI|ensembl:ENSG00000104969(gene)|ensembl:ENST00000221566(transcript)|ensembl:ENST00000676943(transcript)|ensembl:ENST00000677149(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072380"(TRC complex)|go:"GO:0098850"(extrinsic component of synaptic vesicle membrane)|go:"GO:1903070"(negative regulation of ER-associated ubiquitin-dependent protein catabolic process)|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)|go:"GO:1903646"(positive regulation of chaperone-mediated protein folding)|go:"GO:1904288"(BAT3 complex binding)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR032374|mint:O43765|refseq:XP_011526480.1|refseq:NP_003012.1|entrezgene/locuslink:6449(identity)	ensemblfungi:YIL162W(gene)|ensemblfungi:YIL162W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0004564"(beta-fructofuranosidase activity)|go:"GO:0004575"(sucrose alpha-glucosidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005987"(sucrose catabolic process)|go:"GO:0010147"(fructan catabolic process)|go:"GO:0034484"(raffinose catabolic process)|go:"GO:0051670"(inulinase activity)|go:"GO:0071944"(cell periphery)|go:"GO:1902927"(inulin catabolic process)|interpro:IPR001362(Glycoside hydrolase, family 32)|interpro:IPR013148(Glycosyl hydrolases family 32, N-terminal)|interpro:IPR013189(Glycosyl hydrolase family 32, C-terminal)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR018053|interpro:IPR023296|rcsb pdb:4EQV|refseq:NP_012104.1|sgd:S000001424|dip:DIP-5542N|mint:P00724|sgd:YIL162W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:r/Cyj4UJk/cS8QdrbjhTZMPCigI9606	rogid:I6j4m4s8gvTdurEXs3Q7hTrpO30559292	intact-crc:426B8F4EBA892C4B|rigid:v2A+BV0dFY1i3+2cxNb0J5rI+DE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UMX0	uniprotkb:P00431	intact:EBI-741480|uniprotkb:Q8IXS9|uniprotkb:Q8N2Q3|uniprotkb:Q9H0T8|uniprotkb:Q9H3R4|uniprotkb:Q9HAZ5|intact:EBI-28967608|ensembl:ENSP00000365576|uniprotkb:Q5T6J5|uniprotkb:Q5T6J9|uniprotkb:A0A024R284	intact:EBI-4389|uniprotkb:Q6Q5M9|uniprotkb:D6VXC7|ensemblfungi:YKR066C	psi-mi:ubql1_human(display_long)|uniprotkb:Protein linking IAP with cytoskeleton 1(gene name synonym)|uniprotkb:UBQLN1(gene name)|psi-mi:UBQLN1(display_short)|uniprotkb:DA41(gene name synonym)|uniprotkb:PLIC1(gene name synonym)	psi-mi:ccpr_yeast(display_long)|uniprotkb:CCP1(gene name)|psi-mi:CCP1(display_short)|uniprotkb:CCP(gene name synonym)|uniprotkb:CPO(gene name synonym)|uniprotkb:YKR066C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11538266|imex:IM-24995-1670	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000257468|ensembl:ENSP00000257468|ensembl:ENSP00000365576|ensembl:ENSG00000135018(gene)|ensembl:ENST00000376395(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000502"(proteasome complex)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016235"(aggresome)|go:"GO:0016236"(macroautophagy)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0019900"(kinase binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035973"(aggrephagy)|go:"GO:0042802"(identical protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0097352"(autophagosome maturation)|go:"GO:1901340"(negative regulation of store-operated calcium channel activity)|go:"GO:1902175"(regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)|interpro:IPR000626(Ubiquitin)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR028430|interpro:IPR029071|mint:Q9UMX0|rcsb pdb:2JY5|rcsb pdb:2JY6|rcsb pdb:2KLC|reactome:R-HSA-8856825|refseq:NP_038466.2|refseq:NP_444295.1|dip:DIP-41629N|entrezgene/locuslink:29979(identity)	refseq:NP_012992.1|sgd:S000001774|dip:DIP-6251N|ensemblfungi:YKR066C(gene)|ensemblfungi:YKR066C_mRNA(transcript)|go:"GO:0000302"(response to reactive oxygen species)|go:"GO:0004130"(cytochrome-c peroxidase activity)|go:"GO:0004601"(peroxidase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0020037"(heme binding)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0046872"(metal ion binding)|interpro:IPR002016(Haem peroxidase, plant/fungal/bacterial)|interpro:IPR002207(Plant ascorbate peroxidase)|interpro:IPR010255(Haem peroxidase)|interpro:IPR019793|interpro:IPR019794|interpro:IPR044831|rcsb pdb:1A2F|rcsb pdb:1A2G|rcsb pdb:1AA4|rcsb pdb:1AC4|rcsb pdb:1AC8|rcsb pdb:1AEB|rcsb pdb:1AED|rcsb pdb:1AEE|rcsb pdb:1AEF|rcsb pdb:1AEG|rcsb pdb:1AEH|rcsb pdb:1AEJ|rcsb pdb:1AEK|rcsb pdb:1AEM|rcsb pdb:1AEN|rcsb pdb:1AEO|rcsb pdb:1AEQ|rcsb pdb:1AES|rcsb pdb:1AET|rcsb pdb:1AEU|rcsb pdb:1AEV|rcsb pdb:1BEJ|rcsb pdb:1BEK|rcsb pdb:1BEM|rcsb pdb:1BEP|rcsb pdb:1BEQ|rcsb pdb:1BES|rcsb pdb:1BJ9|rcsb pdb:1BVA|rcsb pdb:1CCA|rcsb pdb:1CCB|rcsb pdb:1CCC|rcsb pdb:1CCE|rcsb pdb:1CCG|rcsb pdb:1CCI|rcsb pdb:1CCJ|rcsb pdb:1CCK|rcsb pdb:1CCL|rcsb pdb:1CCP|rcsb pdb:1CMP|rcsb pdb:1CMQ|rcsb pdb:1CMT|rcsb pdb:1CPD|rcsb pdb:1CPE|rcsb pdb:1CPF|rcsb pdb:1CPG|rcsb pdb:1CYF|rcsb pdb:1DCC|rcsb pdb:1DJ1|rcsb pdb:1DJ5|rcsb pdb:1DS4|rcsb pdb:1DSE|rcsb pdb:1DSG|rcsb pdb:1DSO|rcsb pdb:1DSP|rcsb pdb:1EBE|rcsb pdb:1JCI|rcsb pdb:1JDR|rcsb pdb:1KOK|rcsb pdb:1KRJ|rcsb pdb:1KXM|rcsb pdb:1KXN|rcsb pdb:1MK8|rcsb pdb:1MKQ|rcsb pdb:1MKR|rcsb pdb:1ML2|rcsb pdb:1RYC|rcsb pdb:1S6V|rcsb pdb:1S73|rcsb pdb:1SBM|rcsb pdb:1SDQ|rcsb pdb:1SOG|rcsb pdb:1STQ|rcsb pdb:1U74|rcsb pdb:1U75|rcsb pdb:1Z53|rcsb pdb:1ZBY|rcsb pdb:1ZBZ|rcsb pdb:2ANZ|rcsb pdb:2AQD|rcsb pdb:2AS1|rcsb pdb:2AS2|rcsb pdb:2AS3|rcsb pdb:2AS4|rcsb pdb:2AS6|rcsb pdb:2B0Z|rcsb pdb:2B10|rcsb pdb:2B11|rcsb pdb:2B12|rcsb pdb:2BCN|rcsb pdb:2CCP|rcsb pdb:2CEP|rcsb pdb:2CYP|rcsb pdb:2EUN|rcsb pdb:2EUO|rcsb pdb:2EUP|rcsb pdb:2EUQ|rcsb pdb:2EUR|rcsb pdb:2EUS|rcsb pdb:2EUT|rcsb pdb:2EUU|rcsb pdb:2GB8|rcsb pdb:2IA8|rcsb pdb:2ICV|rcsb pdb:2JTI|rcsb pdb:2N18|rcsb pdb:2PCB|rcsb pdb:2PCC|rcsb pdb:2RBT|rcsb pdb:2RBU|rcsb pdb:2RBV|rcsb pdb:2RBW|rcsb pdb:2RBX|rcsb pdb:2RBY|rcsb pdb:2RBZ|rcsb pdb:2RC0|rcsb pdb:2RC1|rcsb pdb:2RC2|rcsb pdb:2V23|rcsb pdb:2V2E|rcsb pdb:2X07|rcsb pdb:2X08|rcsb pdb:2XIL|rcsb pdb:2XJ5|rcsb pdb:2XJ8|rcsb pdb:2Y5A|rcsb pdb:2YCG|rcsb pdb:3CCP|rcsb pdb:3CCX|rcsb pdb:3E2N|rcsb pdb:3E2O|rcsb pdb:3EXB|rcsb pdb:3M23|rcsb pdb:3M25|rcsb pdb:3M26|rcsb pdb:3M27|rcsb pdb:3M28|rcsb pdb:3M29|rcsb pdb:3M2A|rcsb pdb:1CMU|rcsb pdb:3M2B|rcsb pdb:3M2C|rcsb pdb:3M2D|rcsb pdb:3M2E|rcsb pdb:3M2F|rcsb pdb:3M2G|rcsb pdb:3M2H|rcsb pdb:3M2I|rcsb pdb:3R98|rcsb pdb:3R99|rcsb pdb:4A6Z|rcsb pdb:4A71|rcsb pdb:4A78|rcsb pdb:4A7M|rcsb pdb:4CCP|rcsb pdb:4CCX|rcsb pdb:4CVI|rcsb pdb:4CVJ|rcsb pdb:4JB4|rcsb pdb:4NFG|rcsb pdb:4P4Q|rcsb pdb:4XV4|rcsb pdb:4XV5|rcsb pdb:4XV6|rcsb pdb:4XV7|rcsb pdb:4XV8|rcsb pdb:4XVA|rcsb pdb:5CCP|rcsb pdb:5CIB|rcsb pdb:5CIC|rcsb pdb:5CID|rcsb pdb:5CIE|rcsb pdb:5CIF|rcsb pdb:5CIG|rcsb pdb:5CIH|rcsb pdb:5D6M|rcsb pdb:5EJT|rcsb pdb:5EJX|rcsb pdb:6CCP|rcsb pdb:6H08|rcsb pdb:6P41|rcsb pdb:6P42|rcsb pdb:6P43|rcsb pdb:6Y1T|rcsb pdb:6Y2Y|rcsb pdb:7CCP|sgd:YKR066C(identity)	-	-	crc64:A5D26385DA6F0A0B	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:nCFfZbGCTvRYaXhQ4R99XblslvM9606	rogid:LkPXY1wuYoCFzMQPSsAtXZrRi8w559292	intact-crc:D377FB02C9504DD7|rigid:g40l7JFLNqTJJNp+yGPGLvMZdY4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96DZ9-2	uniprotkb:P00431	intact:EBI-11522780|ensembl:ENSP00000352270|ensembl:ENSP00000497215	intact:EBI-4389|uniprotkb:Q6Q5M9|uniprotkb:D6VXC7|ensemblfungi:YKR066C	psi-mi:q96dz9-2(display_long)|uniprotkb:CMTM5(gene name)|psi-mi:CMTM5(display_short)|uniprotkb:CKLFSF5(gene name synonym)|uniprotkb:Chemokine-like factor superfamily member 5(gene name synonym)	psi-mi:ccpr_yeast(display_long)|uniprotkb:CCP1(gene name)|psi-mi:CCP1(display_short)|uniprotkb:CCP(gene name synonym)|uniprotkb:CPO(gene name synonym)|uniprotkb:YKR066C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11538257|imex:IM-24995-1669	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000166091(gene)|ensembl:ENST00000359320(transcript)|ensembl:ENST00000649278(transcript)|intact:EBI-2548702(isoform-parent)|uniprotkb:Q96DZ9-2(isoform-parent)|entrezgene/locuslink:116173(identity)	refseq:NP_012992.1|sgd:S000001774|dip:DIP-6251N|ensemblfungi:YKR066C(gene)|ensemblfungi:YKR066C_mRNA(transcript)|go:"GO:0000302"(response to reactive oxygen species)|go:"GO:0004130"(cytochrome-c peroxidase activity)|go:"GO:0004601"(peroxidase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0020037"(heme binding)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0046872"(metal ion binding)|interpro:IPR002016(Haem peroxidase, plant/fungal/bacterial)|interpro:IPR002207(Plant ascorbate peroxidase)|interpro:IPR010255(Haem peroxidase)|interpro:IPR019793|interpro:IPR019794|interpro:IPR044831|rcsb pdb:1A2F|rcsb pdb:1A2G|rcsb pdb:1AA4|rcsb pdb:1AC4|rcsb pdb:1AC8|rcsb pdb:1AEB|rcsb pdb:1AED|rcsb pdb:1AEE|rcsb pdb:1AEF|rcsb pdb:1AEG|rcsb pdb:1AEH|rcsb pdb:1AEJ|rcsb pdb:1AEK|rcsb pdb:1AEM|rcsb pdb:1AEN|rcsb pdb:1AEO|rcsb pdb:1AEQ|rcsb pdb:1AES|rcsb pdb:1AET|rcsb pdb:1AEU|rcsb pdb:1AEV|rcsb pdb:1BEJ|rcsb pdb:1BEK|rcsb pdb:1BEM|rcsb pdb:1BEP|rcsb pdb:1BEQ|rcsb pdb:1BES|rcsb pdb:1BJ9|rcsb pdb:1BVA|rcsb pdb:1CCA|rcsb pdb:1CCB|rcsb pdb:1CCC|rcsb pdb:1CCE|rcsb pdb:1CCG|rcsb pdb:1CCI|rcsb pdb:1CCJ|rcsb pdb:1CCK|rcsb pdb:1CCL|rcsb pdb:1CCP|rcsb pdb:1CMP|rcsb pdb:1CMQ|rcsb pdb:1CMT|rcsb pdb:1CPD|rcsb pdb:1CPE|rcsb pdb:1CPF|rcsb pdb:1CPG|rcsb pdb:1CYF|rcsb pdb:1DCC|rcsb pdb:1DJ1|rcsb pdb:1DJ5|rcsb pdb:1DS4|rcsb pdb:1DSE|rcsb pdb:1DSG|rcsb pdb:1DSO|rcsb pdb:1DSP|rcsb pdb:1EBE|rcsb pdb:1JCI|rcsb pdb:1JDR|rcsb pdb:1KOK|rcsb pdb:1KRJ|rcsb pdb:1KXM|rcsb pdb:1KXN|rcsb pdb:1MK8|rcsb pdb:1MKQ|rcsb pdb:1MKR|rcsb pdb:1ML2|rcsb pdb:1RYC|rcsb pdb:1S6V|rcsb pdb:1S73|rcsb pdb:1SBM|rcsb pdb:1SDQ|rcsb pdb:1SOG|rcsb pdb:1STQ|rcsb pdb:1U74|rcsb pdb:1U75|rcsb pdb:1Z53|rcsb pdb:1ZBY|rcsb pdb:1ZBZ|rcsb pdb:2ANZ|rcsb pdb:2AQD|rcsb pdb:2AS1|rcsb pdb:2AS2|rcsb pdb:2AS3|rcsb pdb:2AS4|rcsb pdb:2AS6|rcsb pdb:2B0Z|rcsb pdb:2B10|rcsb pdb:2B11|rcsb pdb:2B12|rcsb pdb:2BCN|rcsb pdb:2CCP|rcsb pdb:2CEP|rcsb pdb:2CYP|rcsb pdb:2EUN|rcsb pdb:2EUO|rcsb pdb:2EUP|rcsb pdb:2EUQ|rcsb pdb:2EUR|rcsb pdb:2EUS|rcsb pdb:2EUT|rcsb pdb:2EUU|rcsb pdb:2GB8|rcsb pdb:2IA8|rcsb pdb:2ICV|rcsb pdb:2JTI|rcsb pdb:2N18|rcsb pdb:2PCB|rcsb pdb:2PCC|rcsb pdb:2RBT|rcsb pdb:2RBU|rcsb pdb:2RBV|rcsb pdb:2RBW|rcsb pdb:2RBX|rcsb pdb:2RBY|rcsb pdb:2RBZ|rcsb pdb:2RC0|rcsb pdb:2RC1|rcsb pdb:2RC2|rcsb pdb:2V23|rcsb pdb:2V2E|rcsb pdb:2X07|rcsb pdb:2X08|rcsb pdb:2XIL|rcsb pdb:2XJ5|rcsb pdb:2XJ8|rcsb pdb:2Y5A|rcsb pdb:2YCG|rcsb pdb:3CCP|rcsb pdb:3CCX|rcsb pdb:3E2N|rcsb pdb:3E2O|rcsb pdb:3EXB|rcsb pdb:3M23|rcsb pdb:3M25|rcsb pdb:3M26|rcsb pdb:3M27|rcsb pdb:3M28|rcsb pdb:3M29|rcsb pdb:3M2A|rcsb pdb:1CMU|rcsb pdb:3M2B|rcsb pdb:3M2C|rcsb pdb:3M2D|rcsb pdb:3M2E|rcsb pdb:3M2F|rcsb pdb:3M2G|rcsb pdb:3M2H|rcsb pdb:3M2I|rcsb pdb:3R98|rcsb pdb:3R99|rcsb pdb:4A6Z|rcsb pdb:4A71|rcsb pdb:4A78|rcsb pdb:4A7M|rcsb pdb:4CCP|rcsb pdb:4CCX|rcsb pdb:4CVI|rcsb pdb:4CVJ|rcsb pdb:4JB4|rcsb pdb:4NFG|rcsb pdb:4P4Q|rcsb pdb:4XV4|rcsb pdb:4XV5|rcsb pdb:4XV6|rcsb pdb:4XV7|rcsb pdb:4XV8|rcsb pdb:4XVA|rcsb pdb:5CCP|rcsb pdb:5CIB|rcsb pdb:5CIC|rcsb pdb:5CID|rcsb pdb:5CIE|rcsb pdb:5CIF|rcsb pdb:5CIG|rcsb pdb:5CIH|rcsb pdb:5D6M|rcsb pdb:5EJT|rcsb pdb:5EJX|rcsb pdb:6CCP|rcsb pdb:6H08|rcsb pdb:6P41|rcsb pdb:6P42|rcsb pdb:6P43|rcsb pdb:6Y1T|rcsb pdb:6Y2Y|rcsb pdb:7CCP|sgd:YKR066C(identity)	-	-	crc64:A5D26385DA6F0A0B	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:2TJ7rZKQNb5hH5gz9i+ujOEOIOg9606	rogid:LkPXY1wuYoCFzMQPSsAtXZrRi8w559292	intact-crc:65D05825855CFA19|rigid:/CtEOzSMFSlCAlHj1MH2wk8S2PA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q969L2	uniprotkb:P00431	intact:EBI-944295|uniprotkb:Q6ZMD9|uniprotkb:B2R520|ensembl:ENSP00000479708	intact:EBI-4389|uniprotkb:Q6Q5M9|uniprotkb:D6VXC7|ensemblfungi:YKR066C	psi-mi:mal2_human(display_long)|uniprotkb:MAL2(gene name)|psi-mi:MAL2(display_short)	psi-mi:ccpr_yeast(display_long)|uniprotkb:CCP1(gene name)|psi-mi:CCP1(display_short)|uniprotkb:CCP(gene name synonym)|uniprotkb:CPO(gene name synonym)|uniprotkb:YKR066C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11538248|imex:IM-24995-1668	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_443118.1|ensembl:ENSG00000147676(gene)|ensembl:ENST00000614891(transcript)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019911"(structural constituent of myelin sheath)|go:"GO:0042552"(myelination)|go:"GO:0045056"(transcytosis)|go:"GO:0045121"(membrane raft)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|interpro:IPR008253(Marvel)|interpro:IPR013295("Myelin and lymphocyte (MAL)")|interpro:IPR033240|entrezgene/locuslink:114569(identity)	refseq:NP_012992.1|sgd:S000001774|dip:DIP-6251N|ensemblfungi:YKR066C(gene)|ensemblfungi:YKR066C_mRNA(transcript)|go:"GO:0000302"(response to reactive oxygen species)|go:"GO:0004130"(cytochrome-c peroxidase activity)|go:"GO:0004601"(peroxidase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0020037"(heme binding)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0046872"(metal ion binding)|interpro:IPR002016(Haem peroxidase, plant/fungal/bacterial)|interpro:IPR002207(Plant ascorbate peroxidase)|interpro:IPR010255(Haem peroxidase)|interpro:IPR019793|interpro:IPR019794|interpro:IPR044831|rcsb pdb:1A2F|rcsb pdb:1A2G|rcsb pdb:1AA4|rcsb pdb:1AC4|rcsb pdb:1AC8|rcsb pdb:1AEB|rcsb pdb:1AED|rcsb pdb:1AEE|rcsb pdb:1AEF|rcsb pdb:1AEG|rcsb pdb:1AEH|rcsb pdb:1AEJ|rcsb pdb:1AEK|rcsb pdb:1AEM|rcsb pdb:1AEN|rcsb pdb:1AEO|rcsb pdb:1AEQ|rcsb pdb:1AES|rcsb pdb:1AET|rcsb pdb:1AEU|rcsb pdb:1AEV|rcsb pdb:1BEJ|rcsb pdb:1BEK|rcsb pdb:1BEM|rcsb pdb:1BEP|rcsb pdb:1BEQ|rcsb pdb:1BES|rcsb pdb:1BJ9|rcsb pdb:1BVA|rcsb pdb:1CCA|rcsb pdb:1CCB|rcsb pdb:1CCC|rcsb pdb:1CCE|rcsb pdb:1CCG|rcsb pdb:1CCI|rcsb pdb:1CCJ|rcsb pdb:1CCK|rcsb pdb:1CCL|rcsb pdb:1CCP|rcsb pdb:1CMP|rcsb pdb:1CMQ|rcsb pdb:1CMT|rcsb pdb:1CPD|rcsb pdb:1CPE|rcsb pdb:1CPF|rcsb pdb:1CPG|rcsb pdb:1CYF|rcsb pdb:1DCC|rcsb pdb:1DJ1|rcsb pdb:1DJ5|rcsb pdb:1DS4|rcsb pdb:1DSE|rcsb pdb:1DSG|rcsb pdb:1DSO|rcsb pdb:1DSP|rcsb pdb:1EBE|rcsb pdb:1JCI|rcsb pdb:1JDR|rcsb pdb:1KOK|rcsb pdb:1KRJ|rcsb pdb:1KXM|rcsb pdb:1KXN|rcsb pdb:1MK8|rcsb pdb:1MKQ|rcsb pdb:1MKR|rcsb pdb:1ML2|rcsb pdb:1RYC|rcsb pdb:1S6V|rcsb pdb:1S73|rcsb pdb:1SBM|rcsb pdb:1SDQ|rcsb pdb:1SOG|rcsb pdb:1STQ|rcsb pdb:1U74|rcsb pdb:1U75|rcsb pdb:1Z53|rcsb pdb:1ZBY|rcsb pdb:1ZBZ|rcsb pdb:2ANZ|rcsb pdb:2AQD|rcsb pdb:2AS1|rcsb pdb:2AS2|rcsb pdb:2AS3|rcsb pdb:2AS4|rcsb pdb:2AS6|rcsb pdb:2B0Z|rcsb pdb:2B10|rcsb pdb:2B11|rcsb pdb:2B12|rcsb pdb:2BCN|rcsb pdb:2CCP|rcsb pdb:2CEP|rcsb pdb:2CYP|rcsb pdb:2EUN|rcsb pdb:2EUO|rcsb pdb:2EUP|rcsb pdb:2EUQ|rcsb pdb:2EUR|rcsb pdb:2EUS|rcsb pdb:2EUT|rcsb pdb:2EUU|rcsb pdb:2GB8|rcsb pdb:2IA8|rcsb pdb:2ICV|rcsb pdb:2JTI|rcsb pdb:2N18|rcsb pdb:2PCB|rcsb pdb:2PCC|rcsb pdb:2RBT|rcsb pdb:2RBU|rcsb pdb:2RBV|rcsb pdb:2RBW|rcsb pdb:2RBX|rcsb pdb:2RBY|rcsb pdb:2RBZ|rcsb pdb:2RC0|rcsb pdb:2RC1|rcsb pdb:2RC2|rcsb pdb:2V23|rcsb pdb:2V2E|rcsb pdb:2X07|rcsb pdb:2X08|rcsb pdb:2XIL|rcsb pdb:2XJ5|rcsb pdb:2XJ8|rcsb pdb:2Y5A|rcsb pdb:2YCG|rcsb pdb:3CCP|rcsb pdb:3CCX|rcsb pdb:3E2N|rcsb pdb:3E2O|rcsb pdb:3EXB|rcsb pdb:3M23|rcsb pdb:3M25|rcsb pdb:3M26|rcsb pdb:3M27|rcsb pdb:3M28|rcsb pdb:3M29|rcsb pdb:3M2A|rcsb pdb:1CMU|rcsb pdb:3M2B|rcsb pdb:3M2C|rcsb pdb:3M2D|rcsb pdb:3M2E|rcsb pdb:3M2F|rcsb pdb:3M2G|rcsb pdb:3M2H|rcsb pdb:3M2I|rcsb pdb:3R98|rcsb pdb:3R99|rcsb pdb:4A6Z|rcsb pdb:4A71|rcsb pdb:4A78|rcsb pdb:4A7M|rcsb pdb:4CCP|rcsb pdb:4CCX|rcsb pdb:4CVI|rcsb pdb:4CVJ|rcsb pdb:4JB4|rcsb pdb:4NFG|rcsb pdb:4P4Q|rcsb pdb:4XV4|rcsb pdb:4XV5|rcsb pdb:4XV6|rcsb pdb:4XV7|rcsb pdb:4XV8|rcsb pdb:4XVA|rcsb pdb:5CCP|rcsb pdb:5CIB|rcsb pdb:5CIC|rcsb pdb:5CID|rcsb pdb:5CIE|rcsb pdb:5CIF|rcsb pdb:5CIG|rcsb pdb:5CIH|rcsb pdb:5D6M|rcsb pdb:5EJT|rcsb pdb:5EJX|rcsb pdb:6CCP|rcsb pdb:6H08|rcsb pdb:6P41|rcsb pdb:6P42|rcsb pdb:6P43|rcsb pdb:6Y1T|rcsb pdb:6Y2Y|rcsb pdb:7CCP|sgd:YKR066C(identity)	-	-	crc64:A5D26385DA6F0A0B	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:7SApzrGTzj8V3GIwkdO0X/z6geg9606	rogid:LkPXY1wuYoCFzMQPSsAtXZrRi8w559292	intact-crc:7A035B266315B33D|rigid:BmiQ9cVqnLWMzah7G4aLQsu7hF4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P00431	uniprotkb:Q6RW13-2	intact:EBI-4389|uniprotkb:Q6Q5M9|uniprotkb:D6VXC7|ensemblfungi:YKR066C	intact:EBI-11522760|ensembl:ENSP00000365816	psi-mi:ccpr_yeast(display_long)|uniprotkb:CCP1(gene name)|psi-mi:CCP1(display_short)|uniprotkb:CCP(gene name synonym)|uniprotkb:CPO(gene name synonym)|uniprotkb:YKR066C(locus name)	psi-mi:q6rw13-2(display_long)|uniprotkb:AGTRAP(gene name)|psi-mi:AGTRAP(display_short)|uniprotkb:AT1 receptor-associated protein(gene name synonym)|uniprotkb:ATRAP(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11538239|imex:IM-24995-1667	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012992.1|sgd:S000001774|dip:DIP-6251N|ensemblfungi:YKR066C(gene)|ensemblfungi:YKR066C_mRNA(transcript)|go:"GO:0000302"(response to reactive oxygen species)|go:"GO:0004130"(cytochrome-c peroxidase activity)|go:"GO:0004601"(peroxidase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0020037"(heme binding)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0046872"(metal ion binding)|interpro:IPR002016(Haem peroxidase, plant/fungal/bacterial)|interpro:IPR002207(Plant ascorbate peroxidase)|interpro:IPR010255(Haem peroxidase)|interpro:IPR019793|interpro:IPR019794|interpro:IPR044831|rcsb pdb:1A2F|rcsb pdb:1A2G|rcsb pdb:1AA4|rcsb pdb:1AC4|rcsb pdb:1AC8|rcsb pdb:1AEB|rcsb pdb:1AED|rcsb pdb:1AEE|rcsb pdb:1AEF|rcsb pdb:1AEG|rcsb pdb:1AEH|rcsb pdb:1AEJ|rcsb pdb:1AEK|rcsb pdb:1AEM|rcsb pdb:1AEN|rcsb pdb:1AEO|rcsb pdb:1AEQ|rcsb pdb:1AES|rcsb pdb:1AET|rcsb pdb:1AEU|rcsb pdb:1AEV|rcsb pdb:1BEJ|rcsb pdb:1BEK|rcsb pdb:1BEM|rcsb pdb:1BEP|rcsb pdb:1BEQ|rcsb pdb:1BES|rcsb pdb:1BJ9|rcsb pdb:1BVA|rcsb pdb:1CCA|rcsb pdb:1CCB|rcsb pdb:1CCC|rcsb pdb:1CCE|rcsb pdb:1CCG|rcsb pdb:1CCI|rcsb pdb:1CCJ|rcsb pdb:1CCK|rcsb pdb:1CCL|rcsb pdb:1CCP|rcsb pdb:1CMP|rcsb pdb:1CMQ|rcsb pdb:1CMT|rcsb pdb:1CPD|rcsb pdb:1CPE|rcsb pdb:1CPF|rcsb pdb:1CPG|rcsb pdb:1CYF|rcsb pdb:1DCC|rcsb pdb:1DJ1|rcsb pdb:1DJ5|rcsb pdb:1DS4|rcsb pdb:1DSE|rcsb pdb:1DSG|rcsb pdb:1DSO|rcsb pdb:1DSP|rcsb pdb:1EBE|rcsb pdb:1JCI|rcsb pdb:1JDR|rcsb pdb:1KOK|rcsb pdb:1KRJ|rcsb pdb:1KXM|rcsb pdb:1KXN|rcsb pdb:1MK8|rcsb pdb:1MKQ|rcsb pdb:1MKR|rcsb pdb:1ML2|rcsb pdb:1RYC|rcsb pdb:1S6V|rcsb pdb:1S73|rcsb pdb:1SBM|rcsb pdb:1SDQ|rcsb pdb:1SOG|rcsb pdb:1STQ|rcsb pdb:1U74|rcsb pdb:1U75|rcsb pdb:1Z53|rcsb pdb:1ZBY|rcsb pdb:1ZBZ|rcsb pdb:2ANZ|rcsb pdb:2AQD|rcsb pdb:2AS1|rcsb pdb:2AS2|rcsb pdb:2AS3|rcsb pdb:2AS4|rcsb pdb:2AS6|rcsb pdb:2B0Z|rcsb pdb:2B10|rcsb pdb:2B11|rcsb pdb:2B12|rcsb pdb:2BCN|rcsb pdb:2CCP|rcsb pdb:2CEP|rcsb pdb:2CYP|rcsb pdb:2EUN|rcsb pdb:2EUO|rcsb pdb:2EUP|rcsb pdb:2EUQ|rcsb pdb:2EUR|rcsb pdb:2EUS|rcsb pdb:2EUT|rcsb pdb:2EUU|rcsb pdb:2GB8|rcsb pdb:2IA8|rcsb pdb:2ICV|rcsb pdb:2JTI|rcsb pdb:2N18|rcsb pdb:2PCB|rcsb pdb:2PCC|rcsb pdb:2RBT|rcsb pdb:2RBU|rcsb pdb:2RBV|rcsb pdb:2RBW|rcsb pdb:2RBX|rcsb pdb:2RBY|rcsb pdb:2RBZ|rcsb pdb:2RC0|rcsb pdb:2RC1|rcsb pdb:2RC2|rcsb pdb:2V23|rcsb pdb:2V2E|rcsb pdb:2X07|rcsb pdb:2X08|rcsb pdb:2XIL|rcsb pdb:2XJ5|rcsb pdb:2XJ8|rcsb pdb:2Y5A|rcsb pdb:2YCG|rcsb pdb:3CCP|rcsb pdb:3CCX|rcsb pdb:3E2N|rcsb pdb:3E2O|rcsb pdb:3EXB|rcsb pdb:3M23|rcsb pdb:3M25|rcsb pdb:3M26|rcsb pdb:3M27|rcsb pdb:3M28|rcsb pdb:3M29|rcsb pdb:3M2A|rcsb pdb:1CMU|rcsb pdb:3M2B|rcsb pdb:3M2C|rcsb pdb:3M2D|rcsb pdb:3M2E|rcsb pdb:3M2F|rcsb pdb:3M2G|rcsb pdb:3M2H|rcsb pdb:3M2I|rcsb pdb:3R98|rcsb pdb:3R99|rcsb pdb:4A6Z|rcsb pdb:4A71|rcsb pdb:4A78|rcsb pdb:4A7M|rcsb pdb:4CCP|rcsb pdb:4CCX|rcsb pdb:4CVI|rcsb pdb:4CVJ|rcsb pdb:4JB4|rcsb pdb:4NFG|rcsb pdb:4P4Q|rcsb pdb:4XV4|rcsb pdb:4XV5|rcsb pdb:4XV6|rcsb pdb:4XV7|rcsb pdb:4XV8|rcsb pdb:4XVA|rcsb pdb:5CCP|rcsb pdb:5CIB|rcsb pdb:5CIC|rcsb pdb:5CID|rcsb pdb:5CIE|rcsb pdb:5CIF|rcsb pdb:5CIG|rcsb pdb:5CIH|rcsb pdb:5D6M|rcsb pdb:5EJT|rcsb pdb:5EJX|rcsb pdb:6CCP|rcsb pdb:6H08|rcsb pdb:6P41|rcsb pdb:6P42|rcsb pdb:6P43|rcsb pdb:6Y1T|rcsb pdb:6Y2Y|rcsb pdb:7CCP|sgd:YKR066C(identity)	ensembl:ENSG00000177674(gene)|ensembl:ENST00000376629(transcript)|intact:EBI-741181(isoform-parent)|uniprotkb:Q6RW13-2(isoform-parent)|entrezgene/locuslink:57085(identity)	-	crc64:A5D26385DA6F0A0B	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:LkPXY1wuYoCFzMQPSsAtXZrRi8w559292	rogid:PNzVis/8puQZBJ562gCqZKc078s9606	intact-crc:5E30B97342D2B576|rigid:5UDqt3eotijjhpIZik/N0KGkdIo	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P00431	uniprotkb:P43355	intact:EBI-4389|uniprotkb:Q6Q5M9|uniprotkb:D6VXC7|ensemblfungi:YKR066C	intact:EBI-740978|ensembl:ENSP00000349085|uniprotkb:O00346|uniprotkb:B2RC81	psi-mi:ccpr_yeast(display_long)|uniprotkb:CCP1(gene name)|psi-mi:CCP1(display_short)|uniprotkb:CCP(gene name synonym)|uniprotkb:CPO(gene name synonym)|uniprotkb:YKR066C(locus name)	psi-mi:maga1_human(display_long)|uniprotkb:MAGE-1 antigen(gene name synonym)|uniprotkb:Antigen MZ2-E(gene name synonym)|uniprotkb:Cancer/testis antigen 1.1(gene name synonym)|uniprotkb:MAGEA1(gene name)|psi-mi:MAGEA1(display_short)|uniprotkb:MAGE1(gene name synonym)|uniprotkb:MAGE1A(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11538230|imex:IM-24995-1666	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012992.1|sgd:S000001774|dip:DIP-6251N|ensemblfungi:YKR066C(gene)|ensemblfungi:YKR066C_mRNA(transcript)|go:"GO:0000302"(response to reactive oxygen species)|go:"GO:0004130"(cytochrome-c peroxidase activity)|go:"GO:0004601"(peroxidase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0020037"(heme binding)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0046872"(metal ion binding)|interpro:IPR002016(Haem peroxidase, plant/fungal/bacterial)|interpro:IPR002207(Plant ascorbate peroxidase)|interpro:IPR010255(Haem peroxidase)|interpro:IPR019793|interpro:IPR019794|interpro:IPR044831|rcsb pdb:1A2F|rcsb pdb:1A2G|rcsb pdb:1AA4|rcsb pdb:1AC4|rcsb pdb:1AC8|rcsb pdb:1AEB|rcsb pdb:1AED|rcsb pdb:1AEE|rcsb pdb:1AEF|rcsb pdb:1AEG|rcsb pdb:1AEH|rcsb pdb:1AEJ|rcsb pdb:1AEK|rcsb pdb:1AEM|rcsb pdb:1AEN|rcsb pdb:1AEO|rcsb pdb:1AEQ|rcsb pdb:1AES|rcsb pdb:1AET|rcsb pdb:1AEU|rcsb pdb:1AEV|rcsb pdb:1BEJ|rcsb pdb:1BEK|rcsb pdb:1BEM|rcsb pdb:1BEP|rcsb pdb:1BEQ|rcsb pdb:1BES|rcsb pdb:1BJ9|rcsb pdb:1BVA|rcsb pdb:1CCA|rcsb pdb:1CCB|rcsb pdb:1CCC|rcsb pdb:1CCE|rcsb pdb:1CCG|rcsb pdb:1CCI|rcsb pdb:1CCJ|rcsb pdb:1CCK|rcsb pdb:1CCL|rcsb pdb:1CCP|rcsb pdb:1CMP|rcsb pdb:1CMQ|rcsb pdb:1CMT|rcsb pdb:1CPD|rcsb pdb:1CPE|rcsb pdb:1CPF|rcsb pdb:1CPG|rcsb pdb:1CYF|rcsb pdb:1DCC|rcsb pdb:1DJ1|rcsb pdb:1DJ5|rcsb pdb:1DS4|rcsb pdb:1DSE|rcsb pdb:1DSG|rcsb pdb:1DSO|rcsb pdb:1DSP|rcsb pdb:1EBE|rcsb pdb:1JCI|rcsb pdb:1JDR|rcsb pdb:1KOK|rcsb pdb:1KRJ|rcsb pdb:1KXM|rcsb pdb:1KXN|rcsb pdb:1MK8|rcsb pdb:1MKQ|rcsb pdb:1MKR|rcsb pdb:1ML2|rcsb pdb:1RYC|rcsb pdb:1S6V|rcsb pdb:1S73|rcsb pdb:1SBM|rcsb pdb:1SDQ|rcsb pdb:1SOG|rcsb pdb:1STQ|rcsb pdb:1U74|rcsb pdb:1U75|rcsb pdb:1Z53|rcsb pdb:1ZBY|rcsb pdb:1ZBZ|rcsb pdb:2ANZ|rcsb pdb:2AQD|rcsb pdb:2AS1|rcsb pdb:2AS2|rcsb pdb:2AS3|rcsb pdb:2AS4|rcsb pdb:2AS6|rcsb pdb:2B0Z|rcsb pdb:2B10|rcsb pdb:2B11|rcsb pdb:2B12|rcsb pdb:2BCN|rcsb pdb:2CCP|rcsb pdb:2CEP|rcsb pdb:2CYP|rcsb pdb:2EUN|rcsb pdb:2EUO|rcsb pdb:2EUP|rcsb pdb:2EUQ|rcsb pdb:2EUR|rcsb pdb:2EUS|rcsb pdb:2EUT|rcsb pdb:2EUU|rcsb pdb:2GB8|rcsb pdb:2IA8|rcsb pdb:2ICV|rcsb pdb:2JTI|rcsb pdb:2N18|rcsb pdb:2PCB|rcsb pdb:2PCC|rcsb pdb:2RBT|rcsb pdb:2RBU|rcsb pdb:2RBV|rcsb pdb:2RBW|rcsb pdb:2RBX|rcsb pdb:2RBY|rcsb pdb:2RBZ|rcsb pdb:2RC0|rcsb pdb:2RC1|rcsb pdb:2RC2|rcsb pdb:2V23|rcsb pdb:2V2E|rcsb pdb:2X07|rcsb pdb:2X08|rcsb pdb:2XIL|rcsb pdb:2XJ5|rcsb pdb:2XJ8|rcsb pdb:2Y5A|rcsb pdb:2YCG|rcsb pdb:3CCP|rcsb pdb:3CCX|rcsb pdb:3E2N|rcsb pdb:3E2O|rcsb pdb:3EXB|rcsb pdb:3M23|rcsb pdb:3M25|rcsb pdb:3M26|rcsb pdb:3M27|rcsb pdb:3M28|rcsb pdb:3M29|rcsb pdb:3M2A|rcsb pdb:1CMU|rcsb pdb:3M2B|rcsb pdb:3M2C|rcsb pdb:3M2D|rcsb pdb:3M2E|rcsb pdb:3M2F|rcsb pdb:3M2G|rcsb pdb:3M2H|rcsb pdb:3M2I|rcsb pdb:3R98|rcsb pdb:3R99|rcsb pdb:4A6Z|rcsb pdb:4A71|rcsb pdb:4A78|rcsb pdb:4A7M|rcsb pdb:4CCP|rcsb pdb:4CCX|rcsb pdb:4CVI|rcsb pdb:4CVJ|rcsb pdb:4JB4|rcsb pdb:4NFG|rcsb pdb:4P4Q|rcsb pdb:4XV4|rcsb pdb:4XV5|rcsb pdb:4XV6|rcsb pdb:4XV7|rcsb pdb:4XV8|rcsb pdb:4XVA|rcsb pdb:5CCP|rcsb pdb:5CIB|rcsb pdb:5CIC|rcsb pdb:5CID|rcsb pdb:5CIE|rcsb pdb:5CIF|rcsb pdb:5CIG|rcsb pdb:5CIH|rcsb pdb:5D6M|rcsb pdb:5EJT|rcsb pdb:5EJX|rcsb pdb:6CCP|rcsb pdb:6H08|rcsb pdb:6P41|rcsb pdb:6P42|rcsb pdb:6P43|rcsb pdb:6Y1T|rcsb pdb:6Y2Y|rcsb pdb:7CCP|sgd:YKR066C(identity)	refseq:NP_004979.3|ensembl:ENSG00000198681(gene)|ensembl:ENST00000356661(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|interpro:IPR002190(MAGE protein)|interpro:IPR021072|interpro:IPR030093|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|rcsb pdb:1W72|rcsb pdb:3BO8|dip:DIP-54794N|entrezgene/locuslink:4100(identity)	-	crc64:A5D26385DA6F0A0B	crc64:544EEB1F9F4E9D33	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:LkPXY1wuYoCFzMQPSsAtXZrRi8w559292	rogid:6XW3mnTNM3yvOtXmiFbU8Uz3hjA9606	intact-crc:374602576D85F42A|rigid:VQneuJ3S6d1jG8dpkHfjjzGW/0w	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P01098	uniprotkb:Q96MT8-3	intact:EBI-8080380|intact:MINT-2785764|uniprotkb:D6VRL9|ensemblfungi:YDL130W-A	intact:EBI-11522539|ensembl:ENSP00000507703|ensembl:ENSP00000328382|ensembl:ENSP00000506728|ensembl:ENSP00000506791|ensembl:ENSP00000506828|ensembl:ENSP00000507228	psi-mi:stf1_yeast(display_long)|uniprotkb:STF1(gene name)|psi-mi:STF1(display_short)|uniprotkb:AIS2(gene name synonym)|uniprotkb:ATP synthase F1 subunit epsilon(gene name synonym)|uniprotkb:YDL130BW(orf name)|uniprotkb:YDL130W-A(locus name)	psi-mi:q96mt8-3(display_long)|uniprotkb:CEP63(gene name)|psi-mi:CEP63(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11538313|imex:IM-24995-1675	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010152.1|mint:P01098|interpro:IPR007648(Mitochondrial ATPase inhibitor, IATP)|sgd:S000007232|ensemblfungi:YDL130W-A_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0042030"(ATPase inhibitor activity)|go:"GO:0051117"(ATPase binding)|ensemblfungi:YDL130W-A(gene)|sgd:YDL130W-A(identity)	intact:EBI-741977(isoform-parent)|ensembl:ENST00000332047(transcript)|ensembl:ENST00000682042(transcript)|ensembl:ENST00000682800(transcript)|ensembl:ENST00000682858(transcript)|ensembl:ENST00000683177(transcript)|ensembl:ENST00000683861(transcript)|ensembl:ENSG00000182923(gene)|uniprotkb:Q96MT8-3(isoform-parent)|entrezgene/locuslink:80254(identity)	-	comment:mint|function:This is 1 of 2 proteins that can stabilize the ATPase-inhibitor complex, which normally dissociates when externally added ATP has been consumed	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:YxrqEhb1G8Ln3oLqBYbVRmFM7E4559292	rogid:U0uvVcOCzA8Qp2cCB0ilixgd4Yc9606	intact-crc:CCD5B4D848B8BB45|rigid:EPQDMBePklXPquu8Tb6djvAIJwc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P01097	uniprotkb:Q9C0F1	intact:EBI-8874|ensemblfungi:YDL181W|uniprotkb:D6VRH1	intact:EBI-744115|uniprotkb:A8K8W9|uniprotkb:B3KT53|uniprotkb:Q8IXZ4|uniprotkb:A8MW11|uniprotkb:D3DP42|ensembl:ENSP00000296519|ensembl:ENSP00000380009|ensembl:ENSP00000423153	psi-mi:atif_yeast(display_long)|uniprotkb:INH1(gene name)|psi-mi:INH1(display_short)|uniprotkb:ATP synthase F1 subunit epsilon(gene name synonym)|uniprotkb:D1305(orf name)|uniprotkb:YDL181W(locus name)	psi-mi:cep44_human(display_long)|uniprotkb:HBV PreS1-transactivated protein 3(gene name synonym)|uniprotkb:CEP44(gene name)|psi-mi:CEP44(display_short)|uniprotkb:KIAA1712(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11538304|imex:IM-24995-1674	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YDL181W(gene)|ensemblfungi:YDL181W_mRNA(transcript)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0042030"(ATPase inhibitor activity)|interpro:IPR007648(Mitochondrial ATPase inhibitor, IATP)|rcsb pdb:3ZIA|refseq:NP_010100.1|sgd:S000002340|mint:P01097|dip:DIP-2985N|sgd:YDL181W(identity)	refseq:NP_001035247.1|refseq:NP_001138786.1|refseq:XP_011530587.1|refseq:XP_011530588.1|refseq:XP_011530589.1|refseq:XP_016864143.1|refseq:XP_016864144.1|ensembl:ENSG00000164118(gene)|ensembl:ENST00000296519(transcript)|ensembl:ENST00000396791(transcript)|ensembl:ENST00000503780(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007099"(centriole replication)|go:"GO:0008017"(microtubule binding)|go:"GO:0010457"(centriole-centriole cohesion)|go:"GO:0030496"(midbody)|interpro:IPR029157|interpro:IPR033603|mint:Q9C0F1|entrezgene/locuslink:80817(identity)	-	crc64:E1AF73A47F63CE58	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:3wsu4TOLAZdm97Kfhla8l4UKFEk559292	rogid:gDTC64oDhudGdsssC7v+suIHZkA9606	intact-crc:33483E0BFA7B1E5B|rigid:p+z+1wfAmX+mwOWyhlzLBKNFvtg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P01097	uniprotkb:Q96MT8-3	intact:EBI-8874|ensemblfungi:YDL181W|uniprotkb:D6VRH1	intact:EBI-11522539|ensembl:ENSP00000507703|ensembl:ENSP00000328382|ensembl:ENSP00000506728|ensembl:ENSP00000506791|ensembl:ENSP00000506828|ensembl:ENSP00000507228	psi-mi:atif_yeast(display_long)|uniprotkb:INH1(gene name)|psi-mi:INH1(display_short)|uniprotkb:ATP synthase F1 subunit epsilon(gene name synonym)|uniprotkb:D1305(orf name)|uniprotkb:YDL181W(locus name)	psi-mi:q96mt8-3(display_long)|uniprotkb:CEP63(gene name)|psi-mi:CEP63(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11538295|imex:IM-24995-1673	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YDL181W(gene)|ensemblfungi:YDL181W_mRNA(transcript)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0042030"(ATPase inhibitor activity)|interpro:IPR007648(Mitochondrial ATPase inhibitor, IATP)|rcsb pdb:3ZIA|refseq:NP_010100.1|sgd:S000002340|mint:P01097|dip:DIP-2985N|sgd:YDL181W(identity)	intact:EBI-741977(isoform-parent)|ensembl:ENST00000332047(transcript)|ensembl:ENST00000682042(transcript)|ensembl:ENST00000682800(transcript)|ensembl:ENST00000682858(transcript)|ensembl:ENST00000683177(transcript)|ensembl:ENST00000683861(transcript)|ensembl:ENSG00000182923(gene)|uniprotkb:Q96MT8-3(isoform-parent)|entrezgene/locuslink:80254(identity)	-	crc64:E1AF73A47F63CE58	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:3wsu4TOLAZdm97Kfhla8l4UKFEk559292	rogid:U0uvVcOCzA8Qp2cCB0ilixgd4Yc9606	intact-crc:C88F29A635655DB8|rigid:5ZYraKRCqZFQ5aHI1Bh7OK50qkY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P01123	uniprotkb:Q96CV9-2	intact:EBI-29496|uniprotkb:D6VTJ2|ensemblfungi:YFL038C	intact:EBI-9091423|ensembl:ENSP00000368027|ensembl:ENSP00000368040	psi-mi:ypt1_yeast(display_long)|uniprotkb:YFL038C(locus name)|uniprotkb:YPT1(gene name)|psi-mi:YPT1(display_short)|uniprotkb:YP2(gene name synonym)|uniprotkb:Rab GTPase YPT1(gene name synonym)|uniprotkb:Transport GTPase YPT1(gene name synonym)|uniprotkb:Protein YP2(gene name synonym)	psi-mi:q96cv9-2(display_long)|uniprotkb:E3-14.7K-interacting protein(gene name synonym)|uniprotkb:FIP-2(gene name synonym)|uniprotkb:FIP2(gene name synonym)|uniprotkb:GLC1E(gene name synonym)|uniprotkb:HIP7(gene name synonym)|uniprotkb:HYPL(gene name synonym)|uniprotkb:Huntingtin yeast partner L(gene name synonym)|uniprotkb:Huntingtin-interacting protein 7(gene name synonym)|uniprotkb:Huntingtin-interacting protein L(gene name synonym)|uniprotkb:NEMO-related protein(gene name synonym)|uniprotkb:NRP(gene name synonym)|uniprotkb:Optic neuropathy-inducing protein(gene name synonym)|uniprotkb:Transcription factor IIIA-interacting protein(gene name synonym)|uniprotkb:OPTN(gene name)|psi-mi:OPTN(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11538331|imex:IM-24995-1677	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_116615.1|sgd:S000001856|dip:DIP-2019N|mint:P01123|ensemblfungi:YFL038C(gene)|ensemblfungi:YFL038C_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005795"(Golgi stack)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0012505"(endomembrane system)|go:"GO:0016236"(macroautophagy)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0032456"(endocytic recycling)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0034498"(early endosome to Golgi transport)|go:"GO:0035493"(SNARE complex assembly)|go:"GO:0035494"(SNARE complex disassembly)|go:"GO:0043549"(regulation of kinase activity)|go:"GO:0048194"(Golgi vesicle budding)|go:"GO:0048211"(Golgi vesicle docking)|go:"GO:0061709"(reticulophagy)|go:"GO:0090114"(COPII-coated vesicle budding)|go:"GO:1900101"(regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1990261"(pre-mRNA catabolic process)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|rcsb pdb:1UKV|rcsb pdb:1YZN|rcsb pdb:2BCG|rcsb pdb:3CUE|rcsb pdb:7KMT|reactome:R-SCE-162658|reactome:R-SCE-204005|reactome:R-SCE-6807878|reactome:R-SCE-6811434|reactome:R-SCE-8873719|reactome:R-SCE-8876198|sgd:YFL038C(identity)	intact:EBI-748974(isoform-parent)|ensembl:ENST00000378752(transcript)|ensembl:ENST00000378764(transcript)|ensembl:ENSG00000123240(gene)|uniprotkb:Q96CV9-2(isoform-parent)|entrezgene/locuslink:10133(identity)	-	crc64:F8C704F6BF2D227B	isoform-comment:No experimental confirmation available.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2018/04/06	rogid:IMz/iERXs1zvX+wgJ9x7Uk0ovQ8559292	rogid:ygzEQkiDJwDAMUuFQuOWsSIqwAk9606	intact-crc:6ED0F2EE3E7737F2|rigid:iKF4Z+I6+j8IuUp9FYB7VvlHFgw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96CV9	uniprotkb:P01123	intact:EBI-748974|uniprotkb:Q5T672|uniprotkb:Q5T673|uniprotkb:Q5T674|uniprotkb:Q5T675|uniprotkb:Q7LDL9|uniprotkb:Q8N562|uniprotkb:Q9UET9|uniprotkb:Q9UEV4|uniprotkb:Q9Y218|uniprotkb:B3KP00|uniprotkb:D3DRS4|uniprotkb:D3DRS8|ensembl:ENSP00000263036|ensembl:ENSP00000368021|ensembl:ENSP00000368022|ensembl:ENSP00000368032	intact:EBI-29496|uniprotkb:D6VTJ2|ensemblfungi:YFL038C	psi-mi:optn_human(display_long)|uniprotkb:HYPL(gene name synonym)|uniprotkb:Optic neuropathy-inducing protein(gene name synonym)|uniprotkb:E3-14.7K-interacting protein(gene name synonym)|uniprotkb:FIP-2(gene name synonym)|uniprotkb:Huntingtin-interacting protein L(gene name synonym)|uniprotkb:Huntingtin yeast partner L(gene name synonym)|uniprotkb:NEMO-related protein(gene name synonym)|uniprotkb:Transcription factor IIIA-interacting protein(gene name synonym)|uniprotkb:OPTN(gene name)|psi-mi:OPTN(display_short)|uniprotkb:FIP2(gene name synonym)|uniprotkb:GLC1E(gene name synonym)|uniprotkb:NRP(gene name synonym)|uniprotkb:HIP7(gene name synonym)|uniprotkb:Huntingtin-interacting protein 7(gene name synonym)	psi-mi:ypt1_yeast(display_long)|uniprotkb:YFL038C(locus name)|uniprotkb:YPT1(gene name)|psi-mi:YPT1(display_short)|uniprotkb:YP2(gene name synonym)|uniprotkb:Rab GTPase YPT1(gene name synonym)|uniprotkb:Transport GTPase YPT1(gene name synonym)|uniprotkb:Protein YP2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11538322|imex:IM-24995-1676	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001008212.1|refseq:NP_001008213.1|refseq:NP_001008214.1|refseq:NP_068815.2|ensembl:ENSG00000123240(gene)|ensembl:ENST00000263036(transcript)|ensembl:ENST00000378747(transcript)|ensembl:ENST00000378748(transcript)|ensembl:ENST00000378757(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001920"(negative regulation of receptor recycling)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0007030"(Golgi organization)|go:"GO:0007165"(signal transduction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008219"(cell death)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0061734"(parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:1904417"(positive regulation of xenophagy)|interpro:IPR021063|interpro:IPR032419|interpro:IPR032939|interpro:IPR034735|mint:Q96CV9|rcsb pdb:2LO4|rcsb pdb:2LUE|rcsb pdb:3VTV|rcsb pdb:3VTW|rcsb pdb:5AAZ|rcsb pdb:5B83|rcsb pdb:5EOA|rcsb pdb:5EOF|rcsb pdb:7CZM|reactome:R-HSA-2565942|reactome:R-HSA-8854214|dip:DIP-42001N|entrezgene/locuslink:10133(identity)	refseq:NP_116615.1|sgd:S000001856|dip:DIP-2019N|mint:P01123|ensemblfungi:YFL038C(gene)|ensemblfungi:YFL038C_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005795"(Golgi stack)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0012505"(endomembrane system)|go:"GO:0016236"(macroautophagy)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0032456"(endocytic recycling)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0034498"(early endosome to Golgi transport)|go:"GO:0035493"(SNARE complex assembly)|go:"GO:0035494"(SNARE complex disassembly)|go:"GO:0043549"(regulation of kinase activity)|go:"GO:0048194"(Golgi vesicle budding)|go:"GO:0048211"(Golgi vesicle docking)|go:"GO:0061709"(reticulophagy)|go:"GO:0090114"(COPII-coated vesicle budding)|go:"GO:1900101"(regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1990261"(pre-mRNA catabolic process)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|rcsb pdb:1UKV|rcsb pdb:1YZN|rcsb pdb:2BCG|rcsb pdb:3CUE|rcsb pdb:7KMT|reactome:R-SCE-162658|reactome:R-SCE-204005|reactome:R-SCE-6807878|reactome:R-SCE-6811434|reactome:R-SCE-8873719|reactome:R-SCE-8876198|sgd:YFL038C(identity)	-	-	crc64:F8C704F6BF2D227B	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2018/04/06	rogid:jcCTXDx1bJq3K5mgNUD73jeWeBU9606	rogid:IMz/iERXs1zvX+wgJ9x7Uk0ovQ8559292	intact-crc:099E06B977AAD982|rigid:XU2Ln8eZWI9Gyv83WsGcWnDzStU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96DZ9-2	uniprotkb:P04819	intact:EBI-11522780|ensembl:ENSP00000352270|ensembl:ENSP00000497215	intact:EBI-5991|uniprotkb:Q12736|uniprotkb:D6VRI7|ensemblfungi:YDL164C	psi-mi:q96dz9-2(display_long)|uniprotkb:CMTM5(gene name)|psi-mi:CMTM5(display_short)|uniprotkb:CKLFSF5(gene name synonym)|uniprotkb:Chemokine-like factor superfamily member 5(gene name synonym)	psi-mi:dnli1_yeast(display_long)|uniprotkb:YDL164C(locus name)|uniprotkb:CDC9(gene name)|psi-mi:CDC9(display_short)|uniprotkb:DNA ligase I(gene name synonym)|uniprotkb:Polydeoxyribonucleotide synthase [ATP] 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11538376|imex:IM-24995-1682	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000166091(gene)|ensembl:ENST00000359320(transcript)|ensembl:ENST00000649278(transcript)|intact:EBI-2548702(isoform-parent)|uniprotkb:Q96DZ9-2(isoform-parent)|entrezgene/locuslink:116173(identity)	refseq:NP_010117.1|sgd:S000002323|dip:DIP-5630N|mint:P04819|ensemblfungi:YDL164C(gene)|ensemblfungi:YDL164C_mRNA(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003677"(DNA binding)|go:"GO:0003910"("DNA ligase (ATP) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006266"(DNA ligation)|go:"GO:0006273"(lagging strand elongation)|go:"GO:0006284"(base-excision repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0035753"(maintenance of DNA trinucleotide repeats)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:0071897"(DNA biosynthetic process)|go:"GO:1903461"(Okazaki fragment processing involved in mitotic DNA replication)|interpro:IPR000977(ATP-dependent DNA ligase)|interpro:IPR012308(DNA ligase, N-terminal)|interpro:IPR012309(ATP dependent DNA ligase, C-terminal)|interpro:IPR012310(ATP dependent DNA ligase, central)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR016059(ATP-dependent DNA ligase, conserved site)|interpro:IPR036599|rcsb pdb:2OD8|reactome:R-SCE-5358565|reactome:R-SCE-5358606|reactome:R-SCE-6782210|reactome:R-SCE-69183|sgd:YDL164C(identity)	-	-	crc64:B7C2ECAF5C61CAE7	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:2TJ7rZKQNb5hH5gz9i+ujOEOIOg9606	rogid:sl00ubCmkTFwW2bznucqEF60I3M559292	intact-crc:18DA106B735CD368|rigid:3eAaeCLoVTYQ+m29PX6da1v9rFg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P04819	uniprotkb:Q969L2	intact:EBI-5991|uniprotkb:Q12736|uniprotkb:D6VRI7|ensemblfungi:YDL164C	intact:EBI-944295|uniprotkb:Q6ZMD9|uniprotkb:B2R520|ensembl:ENSP00000479708	psi-mi:dnli1_yeast(display_long)|uniprotkb:YDL164C(locus name)|uniprotkb:CDC9(gene name)|psi-mi:CDC9(display_short)|uniprotkb:DNA ligase I(gene name synonym)|uniprotkb:Polydeoxyribonucleotide synthase [ATP] 1(gene name synonym)	psi-mi:mal2_human(display_long)|uniprotkb:MAL2(gene name)|psi-mi:MAL2(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11538367|imex:IM-24995-1681	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010117.1|sgd:S000002323|dip:DIP-5630N|mint:P04819|ensemblfungi:YDL164C(gene)|ensemblfungi:YDL164C_mRNA(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003677"(DNA binding)|go:"GO:0003910"("DNA ligase (ATP) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006266"(DNA ligation)|go:"GO:0006273"(lagging strand elongation)|go:"GO:0006284"(base-excision repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0035753"(maintenance of DNA trinucleotide repeats)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:0071897"(DNA biosynthetic process)|go:"GO:1903461"(Okazaki fragment processing involved in mitotic DNA replication)|interpro:IPR000977(ATP-dependent DNA ligase)|interpro:IPR012308(DNA ligase, N-terminal)|interpro:IPR012309(ATP dependent DNA ligase, C-terminal)|interpro:IPR012310(ATP dependent DNA ligase, central)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR016059(ATP-dependent DNA ligase, conserved site)|interpro:IPR036599|rcsb pdb:2OD8|reactome:R-SCE-5358565|reactome:R-SCE-5358606|reactome:R-SCE-6782210|reactome:R-SCE-69183|sgd:YDL164C(identity)	refseq:NP_443118.1|ensembl:ENSG00000147676(gene)|ensembl:ENST00000614891(transcript)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019911"(structural constituent of myelin sheath)|go:"GO:0042552"(myelination)|go:"GO:0045056"(transcytosis)|go:"GO:0045121"(membrane raft)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|interpro:IPR008253(Marvel)|interpro:IPR013295("Myelin and lymphocyte (MAL)")|interpro:IPR033240|entrezgene/locuslink:114569(identity)	-	crc64:B7C2ECAF5C61CAE7	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:sl00ubCmkTFwW2bznucqEF60I3M559292	rogid:7SApzrGTzj8V3GIwkdO0X/z6geg9606	intact-crc:D89594A754F7566A|rigid:/Drab1hR2vpQO5x3xAkCFelwpTQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P04819	uniprotkb:Q6RW13-2	intact:EBI-5991|uniprotkb:Q12736|uniprotkb:D6VRI7|ensemblfungi:YDL164C	intact:EBI-11522760|ensembl:ENSP00000365816	psi-mi:dnli1_yeast(display_long)|uniprotkb:YDL164C(locus name)|uniprotkb:CDC9(gene name)|psi-mi:CDC9(display_short)|uniprotkb:DNA ligase I(gene name synonym)|uniprotkb:Polydeoxyribonucleotide synthase [ATP] 1(gene name synonym)	psi-mi:q6rw13-2(display_long)|uniprotkb:AGTRAP(gene name)|psi-mi:AGTRAP(display_short)|uniprotkb:AT1 receptor-associated protein(gene name synonym)|uniprotkb:ATRAP(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11538358|imex:IM-24995-1680	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010117.1|sgd:S000002323|dip:DIP-5630N|mint:P04819|ensemblfungi:YDL164C(gene)|ensemblfungi:YDL164C_mRNA(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003677"(DNA binding)|go:"GO:0003910"("DNA ligase (ATP) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006266"(DNA ligation)|go:"GO:0006273"(lagging strand elongation)|go:"GO:0006284"(base-excision repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0035753"(maintenance of DNA trinucleotide repeats)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:0071897"(DNA biosynthetic process)|go:"GO:1903461"(Okazaki fragment processing involved in mitotic DNA replication)|interpro:IPR000977(ATP-dependent DNA ligase)|interpro:IPR012308(DNA ligase, N-terminal)|interpro:IPR012309(ATP dependent DNA ligase, C-terminal)|interpro:IPR012310(ATP dependent DNA ligase, central)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR016059(ATP-dependent DNA ligase, conserved site)|interpro:IPR036599|rcsb pdb:2OD8|reactome:R-SCE-5358565|reactome:R-SCE-5358606|reactome:R-SCE-6782210|reactome:R-SCE-69183|sgd:YDL164C(identity)	ensembl:ENSG00000177674(gene)|ensembl:ENST00000376629(transcript)|intact:EBI-741181(isoform-parent)|uniprotkb:Q6RW13-2(isoform-parent)|entrezgene/locuslink:57085(identity)	-	crc64:B7C2ECAF5C61CAE7	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:sl00ubCmkTFwW2bznucqEF60I3M559292	rogid:PNzVis/8puQZBJ562gCqZKc078s9606	intact-crc:BE86DA5E37ED3E15|rigid:BQ0xwnjpl3+ZguuTGK0dY4JVs44	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P04819	uniprotkb:Q15041	intact:EBI-5991|uniprotkb:Q12736|uniprotkb:D6VRI7|ensemblfungi:YDL164C	intact:EBI-714543|ensembl:ENSP00000306788|uniprotkb:B7Z6S5|uniprotkb:B7Z791|uniprotkb:F5GXP4	psi-mi:dnli1_yeast(display_long)|uniprotkb:YDL164C(locus name)|uniprotkb:CDC9(gene name)|psi-mi:CDC9(display_short)|uniprotkb:DNA ligase I(gene name synonym)|uniprotkb:Polydeoxyribonucleotide synthase [ATP] 1(gene name synonym)	psi-mi:ar6p1_human(display_long)|uniprotkb:ARL6IP(gene name synonym)|uniprotkb:ARL6IP1(gene name)|psi-mi:ARL6IP1(display_short)|uniprotkb:KIAA0069(gene name synonym)|uniprotkb:ARMER(gene name synonym)|uniprotkb:Apoptotic regulator in the membrane of the endoplasmic reticulum(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11538349|imex:IM-24995-1679	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010117.1|sgd:S000002323|dip:DIP-5630N|mint:P04819|ensemblfungi:YDL164C(gene)|ensemblfungi:YDL164C_mRNA(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003677"(DNA binding)|go:"GO:0003910"("DNA ligase (ATP) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006266"(DNA ligation)|go:"GO:0006273"(lagging strand elongation)|go:"GO:0006284"(base-excision repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0035753"(maintenance of DNA trinucleotide repeats)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:0071897"(DNA biosynthetic process)|go:"GO:1903461"(Okazaki fragment processing involved in mitotic DNA replication)|interpro:IPR000977(ATP-dependent DNA ligase)|interpro:IPR012308(DNA ligase, N-terminal)|interpro:IPR012309(ATP dependent DNA ligase, C-terminal)|interpro:IPR012310(ATP dependent DNA ligase, central)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR016059(ATP-dependent DNA ligase, conserved site)|interpro:IPR036599|rcsb pdb:2OD8|reactome:R-SCE-5358565|reactome:R-SCE-5358606|reactome:R-SCE-6782210|reactome:R-SCE-69183|sgd:YDL164C(identity)	refseq:NP_055976.1|ensembl:ENSG00000170540(gene)|ensembl:ENST00000304414(transcript)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006613"(cotranslational protein targeting to membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0071787"(endoplasmic reticulum tubular network formation)|go:"GO:1903371"(regulation of endoplasmic reticulum tubular network organization)|go:"GO:1990809"(endoplasmic reticulum tubular network membrane organization)|interpro:IPR033301|mint:Q15041|go:"GO:0002038"(positive regulation of L-glutamate import across plasma membrane)|refseq:NP_001300787.1|entrezgene/locuslink:23204(identity)	-	crc64:B7C2ECAF5C61CAE7	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:sl00ubCmkTFwW2bznucqEF60I3M559292	rogid:3fjkoyvUx25po7xsPcXgpjEeLJg9606	intact-crc:63D00C0421F30D13|rigid:ERVbPUWiIjvEJNHRtyq/VzxEWUk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P04046	uniprotkb:P63279	intact:EBI-14238|ensemblfungi:YMR300C|uniprotkb:D6W0C7	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	psi-mi:pur1_yeast(display_long)|uniprotkb:Glutamine phosphoribosylpyrophosphate amidotransferase(gene name synonym)|uniprotkb:ADE4(gene name)|psi-mi:ADE4(display_short)|uniprotkb:YMR300C(locus name)|uniprotkb:YM9952.02C(orf name)	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11538340|imex:IM-24995-1678	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014029.1|sgd:S000004915|ensemblfungi:YMR300C(gene)|go:"GO:0009116"(nucleoside metabolic process)|go:"GO:0046872"(metal ion binding)|interpro:IPR000836(Phosphoribosyltransferase)|interpro:IPR005854(Amidophosphoribosyl transferase)|ensemblfungi:YMR300C_mRNA(transcript)|go:"GO:0004044"(amidophosphoribosyltransferase activity)|go:"GO:0005737"(cytoplasm)|interpro:IPR017932|interpro:IPR029055|interpro:IPR029057|interpro:IPR035584|go:"GO:0006164"(purine nucleotide biosynthetic process)|go:"GO:0006189"('de novo' IMP biosynthetic process)|go:"GO:0006541"(glutamine metabolic process)|go:"GO:0009113"(purine nucleobase biosynthetic process)|mint:P04046|dip:DIP-6727N|sgd:YMR300C(identity)	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N|entrezgene/locuslink:7329(identity)	-	crc64:1FE7A6F5B7C96710	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:v3Q2NjIC4OuMxGAFnC+1r4y70mw559292	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	intact-crc:BED1313683990532|rigid:emC0gnGMB34N9GN/LUQPL3YvnPk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96BA8	uniprotkb:P05375	intact:EBI-6942903|ensembl:ENSP00000481956|intact:MINT-268046|intact:MINT-8162577|uniprotkb:Q8N2D5|uniprotkb:Q96CP0	intact:EBI-13119|uniprotkb:D6VWP3|ensemblfungi:YJR073C	psi-mi:cr3l1_human(display_long)|uniprotkb:CREB3L1(gene name)|psi-mi:CREB3L1(display_short)|uniprotkb:OASIS(gene name synonym)|uniprotkb:PSEC0238(orf name)|uniprotkb:Old astrocyte specifically-induced substance(gene name synonym)	psi-mi:plmt_yeast(display_long)|uniprotkb:OPI3(gene name)|psi-mi:OPI3(display_short)|uniprotkb:PEM2(gene name synonym)|uniprotkb:Overproducer of inositol protein 3(gene name synonym)|uniprotkb:Phospholipid methyltransferase(gene name synonym)|uniprotkb:J1824(orf name)|uniprotkb:YJR073C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11538385|imex:IM-24995-1683	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157613(gene)|ensembl:ENST00000621158(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0070278"(extracellular matrix constituent secretion)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029805|mint:Q96BA8|reactome:R-HSA-8874211|refseq:NP_443086.1|entrezgene/locuslink:90993(identity)	refseq:NP_012607.1|sgd:S000003834|reactome:R-SCE-1483191|dip:DIP-2888N|ensemblfungi:YJR073C(gene)|ensemblfungi:YJR073C_mRNA(transcript)|go:"GO:0000773"(phosphatidyl-N-methylethanolamine N-methyltransferase activity)|go:"GO:0004608"(phosphatidylethanolamine N-methyltransferase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006656"(phosphatidylcholine biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032259"(methylation)|go:"GO:0071944"(cell periphery)|go:"GO:0080101"(phosphatidyl-N-dimethylethanolamine N-methyltransferase activity)|interpro:IPR007318(Phospholipid methyltransferase)|interpro:IPR024960|sgd:YJR073C(identity)	-	comment:mint|function:"Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE"	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:sMWUFmBeBBCO+T0Y2CuB/un1lBg9606	rogid:5jLJ+pCvOmgw3FFJDmZ5HOwI+BI559292	intact-crc:920179B217FBCF9D|rigid:mak0qGTKwIm2BLg50IeXlVkEyiA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P06782	uniprotkb:Q8N5R6	intact:EBI-17516|uniprotkb:D6VTA0|ensemblfungi:YDR477W	intact:EBI-740841|intact:EBI-953781|uniprotkb:B3KQ49|uniprotkb:A8K3U4|uniprotkb:A8MPQ6|uniprotkb:A8MV61|uniprotkb:A8MVU9|uniprotkb:Q9H5Q6|uniprotkb:Q8TAX6|intact:EBI-2320546|intact:EBI-11522976	psi-mi:snf1_yeast(display_long)|uniprotkb:SNF1(gene name)|psi-mi:SNF1(display_short)|uniprotkb:CAT1(gene name synonym)|uniprotkb:CCR1(gene name synonym)|uniprotkb:GLC2(gene name synonym)|uniprotkb:PAS14(gene name synonym)|uniprotkb:Sucrose nonfermentating protein 1(gene name synonym)|uniprotkb:D8035.20(orf name)|uniprotkb:YDR477W(locus name)	psi-mi:ccd33_human(display_long)|uniprotkb:CCDC33(gene name)|psi-mi:CCDC33(display_short)|uniprotkb:Cancer/testis antigen 61(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11538440|imex:IM-24995-1689	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010765.3|sgd:S000002885|ensemblfungi:YDR477W(gene)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0071940"(fungal-type cell wall assembly)|go:"GO:0090606"(single-species surface biofilm formation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900436"(positive regulation of filamentous growth of a population of unicellular organisms in response to starvation)|go:"GO:2000222"(positive regulation of pseudohyphal growth)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013896(Ubiquitin-associated region 2)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR028375|interpro:IPR032270|rcsb pdb:2FH9|rcsb pdb:2QLV|rcsb pdb:3DAE|rcsb pdb:3HYH|rcsb pdb:3MN3|rcsb pdb:3T4N|rcsb pdb:3TDH|rcsb pdb:3TE5|reactome:R-SCE-1632852|reactome:R-SCE-163680|reactome:R-SCE-200425|reactome:R-SCE-380972|ensemblfungi:YDR477W_mRNA(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000144"(cellular bud neck septin ring)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004679"(AMP-activated protein kinase activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005641"(nuclear envelope lumen)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0007155"(cell adhesion)|go:"GO:0016239"(positive regulation of macroautophagy)|dip:DIP-18N|mint:P06782|sgd:YDR477W(identity)	refseq:NP_079331.3|interpro:IPR000008(C2 calcium-dependent membrane targeting)|go:"GO:0005777"(peroxisome)|refseq:NP_001274110.1|refseq:NP_877592.2|mint:Q8N5R6|interpro:IPR035892|interpro:IPR039889|entrezgene/locuslink:80125(identity)	-	crc64:F5C63565C986C4E3	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2021/11/30	rogid:O/SAW1kJE3fpoXPHGLG01i9RePs559292	rogid:eEIn7pQyfdHWx8TeLJpYy0i/gww9606	intact-crc:FC01E666CB86E47B|rigid:ZRLG728wbypxjsqZJneIKHvxyVk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P06782	uniprotkb:P50222	intact:EBI-17516|uniprotkb:D6VTA0|ensemblfungi:YDR477W	intact:EBI-748397|uniprotkb:O75263|ensembl:ENSP00000262041|uniprotkb:Q9UPL6|uniprotkb:B2R8I7|intact:EBI-10172134|intact:EBI-11522964|intact:EBI-11750003|intact:EBI-12702266|uniprotkb:A4D127	psi-mi:snf1_yeast(display_long)|uniprotkb:SNF1(gene name)|psi-mi:SNF1(display_short)|uniprotkb:CAT1(gene name synonym)|uniprotkb:CCR1(gene name synonym)|uniprotkb:GLC2(gene name synonym)|uniprotkb:PAS14(gene name synonym)|uniprotkb:Sucrose nonfermentating protein 1(gene name synonym)|uniprotkb:D8035.20(orf name)|uniprotkb:YDR477W(locus name)	psi-mi:meox2_human(display_long)|uniprotkb:Mesenchyme homeobox 2(gene name synonym)|uniprotkb:Growth arrest-specific homeobox(gene name synonym)|uniprotkb:MEOX2(gene name)|psi-mi:MEOX2(display_short)|uniprotkb:GAX(gene name synonym)|uniprotkb:MOX2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11538431|imex:IM-24995-1688	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010765.3|sgd:S000002885|ensemblfungi:YDR477W(gene)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0071940"(fungal-type cell wall assembly)|go:"GO:0090606"(single-species surface biofilm formation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900436"(positive regulation of filamentous growth of a population of unicellular organisms in response to starvation)|go:"GO:2000222"(positive regulation of pseudohyphal growth)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013896(Ubiquitin-associated region 2)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR028375|interpro:IPR032270|rcsb pdb:2FH9|rcsb pdb:2QLV|rcsb pdb:3DAE|rcsb pdb:3HYH|rcsb pdb:3MN3|rcsb pdb:3T4N|rcsb pdb:3TDH|rcsb pdb:3TE5|reactome:R-SCE-1632852|reactome:R-SCE-163680|reactome:R-SCE-200425|reactome:R-SCE-380972|ensemblfungi:YDR477W_mRNA(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000144"(cellular bud neck septin ring)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004679"(AMP-activated protein kinase activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005641"(nuclear envelope lumen)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0007155"(cell adhesion)|go:"GO:0016239"(positive regulation of macroautophagy)|dip:DIP-18N|mint:P06782|sgd:YDR477W(identity)	ensembl:ENSG00000106511(gene)|ensembl:ENST00000262041(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0001757"(somite specification)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007275"(multicellular organism development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008015"(blood circulation)|go:"GO:0016607"(nuclear speck)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060173"(limb development)|go:"GO:0061053"(somite development)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR042634|refseq:NP_005915.2|entrezgene/locuslink:4223(identity)	-	crc64:F5C63565C986C4E3	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2017/05/26	rogid:O/SAW1kJE3fpoXPHGLG01i9RePs559292	rogid:fMv0ruKikzQ3MC0PBvJ3pOAjW+U9606	intact-crc:A22F45CB316262BC|rigid:PszU6JY+588CpoIjGSz9UPjgW0o	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8N6L0	uniprotkb:P06197	intact:EBI-749265|uniprotkb:Q96MC3|ensembl:ENSP00000404220	intact:EBI-13458|uniprotkb:D6W4B2|ensemblfungi:YPR113W	psi-mi:kash5_human(display_long)|uniprotkb:KASH5(gene name)|psi-mi:KASH5(display_short)|uniprotkb:CCDC155(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 155(gene name synonym)|uniprotkb:KASH domain-containing protein 5(gene name synonym)	psi-mi:pis_yeast(display_long)|uniprotkb:PIS1(gene name)|psi-mi:PIS1(display_short)|uniprotkb:Phosphatidylinositol synthase(gene name synonym)|uniprotkb:PIS(gene name synonym)|uniprotkb:P8283.5(orf name)|uniprotkb:YPR113W(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11538422|imex:IM-24995-1687	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_653289.3|ensembl:ENSG00000161609(gene)|ensembl:ENST00000447857(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034397"(telomere localization)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051225"(spindle assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0090172"(microtubule cytoskeleton organization involved in homologous chromosome segregation)|go:"GO:0090220"(chromosome localization to nuclear envelope involved in homologous chromosome segregation)|go:"GO:0090619"(meiotic spindle pole)|interpro:IPR011992(EF-Hand type)|interpro:IPR028168|interpro:IPR028170|interpro:IPR039508|mint:Q8N6L0|rcsb pdb:6R2I|rcsb pdb:6WMF|entrezgene/locuslink:147872(identity)	refseq:NP_015438.1|sgd:S000006317|mint:P06197|dip:DIP-3815N|ensemblfungi:YPR113W(gene)|ensemblfungi:YPR113W_mRNA(transcript)|go:"GO:0003881"(CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000462(CDP-alcohol phosphatidyltransferase)|interpro:IPR014387(CDP-diacylglycerol-inositol 3-phosphatidyltransferase, eukaryote)|interpro:IPR043130|reactome:R-SCE-1483226|sgd:YPR113W(identity)	-	-	crc64:6E2E62252B3CB5E2	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Wl9L7AcvDHCZuKjYLn8QgGIbZTc9606	rogid:tdcTqpKpIDy8+8RRpLxehIeTrRU559292	intact-crc:BADAA3370A9145CD|rigid:9RrThZupbs1yPSEiQudQWJFGrpk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P05759	uniprotkb:Q13137	intact:EBI-16127|uniprotkb:P14800|ensemblfungi:YLR167W|uniprotkb:D6VYH3|uniprotkb:P04838|uniprotkb:P61864|uniprotkb:Q6LA96	intact:EBI-739580|uniprotkb:B4DDC4|uniprotkb:E7ENK0|uniprotkb:Q53FQ5|uniprotkb:Q53HB5|uniprotkb:Q6IBN9|uniprotkb:Q9BTF7|uniprotkb:B2RBT0|ensembl:ENSP00000258947|uniprotkb:B4E0C0|uniprotkb:E7ETP5|uniprotkb:B4DDT4|uniprotkb:B4DP36|uniprotkb:E9PBE5	psi-mi:rs31_yeast(display_long)|uniprotkb:RPS31(gene name)|psi-mi:RPS31(display_short)|uniprotkb:UBI3(gene name synonym)|uniprotkb:YLR167W(locus name)|uniprotkb:L9470.14(orf name)|uniprotkb:RPS37(gene name synonym)	psi-mi:caco2_human(display_long)|uniprotkb:CALCOCO2(gene name)|psi-mi:CALCOCO2(display_short)|uniprotkb:NDP52(gene name synonym)|uniprotkb:Nuclear domain 10 protein NDP52(gene name synonym)|uniprotkb:Antigen nuclear dot 52 kDa protein(gene name synonym)|uniprotkb:Nuclear dot protein 52(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11538413|imex:IM-24995-1686	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:6WOO|rcsb pdb:6Z6J|rcsb pdb:6Z6K|rcsb pdb:6ZCE|rcsb pdb:6ZQH|rcsb pdb:6ZU9|rcsb pdb:6ZVI|rcsb pdb:7A1G|rcsb pdb:7B7D|rcsb pdb:7NRC|rcsb pdb:7NRD|rcsb pdb:5WYJ|rcsb pdb:6EML|rcsb pdb:6GQ1|rcsb pdb:6GQB|rcsb pdb:6GQV|rcsb pdb:6HHQ|rcsb pdb:6I7O|rcsb pdb:6Q8Y|rcsb pdb:6RBE|rcsb pdb:6S47|rcsb pdb:6SNT|rcsb pdb:6SV4|rcsb pdb:6T4Q|rcsb pdb:6T7I|rcsb pdb:6T7T|rcsb pdb:6T83|rcsb pdb:6TB3|rcsb pdb:6TNU|rcsb pdb:6WDR|ensemblfungi:YLR167W(gene)|ensemblfungi:YLR167W_mRNA(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0002109"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, LSU-rRNA,5S)")|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0031386"(protein tag)|rcsb pdb:4U56|rcsb pdb:4U6F|rcsb pdb:4V88|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0046872"(metal ion binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR002906(Ribosomal protein S27a)|interpro:IPR011332(Ribosomal protein, zinc-binding)|interpro:IPR019954|interpro:IPR019956|interpro:IPR029071|rcsb pdb:4V8Y|interpro:IPR038582|rcsb pdb:3J6X|rcsb pdb:3J6Y|rcsb pdb:3J77|rcsb pdb:4V8Z|rcsb pdb:3J78|rcsb pdb:4U3M|rcsb pdb:4U3N|rcsb pdb:4U3U|rcsb pdb:4U4N|rcsb pdb:4U4O|rcsb pdb:4U4Q|rcsb pdb:4U4R|rcsb pdb:4U4U|rcsb pdb:4U4Y|rcsb pdb:4U4Z|rcsb pdb:4U50|rcsb pdb:4U51|rcsb pdb:4U52|rcsb pdb:4U53|rcsb pdb:4U55|rcsb pdb:4V92|rcsb pdb:5DAT|rcsb pdb:5DC3|rcsb pdb:5DGE|rcsb pdb:5DGF|rcsb pdb:5DGV|rcsb pdb:5FCI|rcsb pdb:5FCJ|rcsb pdb:5I4L|rcsb pdb:5JUO|rcsb pdb:5JUP|rcsb pdb:5JUS|rcsb pdb:5JUT|rcsb pdb:5JUU|rcsb pdb:5L6H|rcsb pdb:5L6I|rcsb pdb:5L6J|rcsb pdb:5LYB|rcsb pdb:5M1J|rcsb pdb:5MC6|rcsb pdb:5NDG|rcsb pdb:5NDW|rcsb pdb:5OBM|rcsb pdb:5TGA|rcsb pdb:5TGM|rcsb pdb:5U4P|refseq:NP_013268.1|sgd:S000004157|dip:DIP-6389N|mint:P05759|sgd:YLR167W(identity)	refseq:NP_001248319.1|refseq:NP_001248320.1|refseq:NP_001248322.1|refseq:NP_005822.1|ensembl:ENSG00000136436(gene)|ensembl:ENST00000258947(transcript)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016032"(viral process)|go:"GO:0016605"(PML body)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0098792"(xenophagy)|go:"GO:1901098"(positive regulation of autophagosome maturation)|interpro:IPR041611|interpro:IPR041641|mint:Q13137|rcsb pdb:2MXP|rcsb pdb:3VVV|rcsb pdb:3VVW|rcsb pdb:4GXL|rcsb pdb:4HAN|rcsb pdb:4XKL|rcsb pdb:5AAQ|rcsb pdb:5Z7A|rcsb pdb:5Z7L|refseq:NP_001248324.1|dip:DIP-57534N|entrezgene/locuslink:10241(identity)	-	-	crc64:609B121DA1A9DCB8	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:y4P4l0xJoM/1nElb1uDDTpc3oJA559292	rogid:N/GPJUGBK+Dh5Cg+csmafphuo9M9606	intact-crc:34394B675482BCB2|rigid:uJnikN2n0oe5MdDeAivESK4TArY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q92997	uniprotkb:P05738	intact:EBI-739789|uniprotkb:O14642|uniprotkb:Q13531|uniprotkb:Q8N5E9|uniprotkb:Q92607|uniprotkb:D3DNT0|intact:EBI-11081380|uniprotkb:B4E3E5|ensembl:ENSP00000316054	intact:EBI-15439|uniprotkb:D6VU02|ensemblfungi:YGL147C	psi-mi:dvl3_human(display_long)|uniprotkb:DVL3(gene name)|psi-mi:DVL3(display_short)|uniprotkb:KIAA0208(gene name synonym)|uniprotkb:DSH homolog 3(gene name synonym)	psi-mi:rl9a_yeast(display_long)|uniprotkb:RPL9A(gene name)|psi-mi:RPL9A(display_short)|uniprotkb:RPL9(gene name synonym)|uniprotkb:RPL8A(gene name synonym)|uniprotkb:L8(gene name synonym)|uniprotkb:YL11(gene name synonym)|uniprotkb:RP24(gene name synonym)|uniprotkb:YGL147C(locus name)|uniprotkb:Large ribosomal subunit protein uL6-A(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11538404|imex:IM-24995-1685	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004414.3|dip:DIP-34509N|ensembl:ENSG00000161202(gene)|ensembl:ENST00000313143(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002020"(protease binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005109"(frizzled binding)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0038031"(non-canonical Wnt signaling pathway via JNK cascade)|go:"GO:0042493"|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050821"(protein stabilization)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0150012"(positive regulation of neuron projection arborization)|go:"GO:1903827"|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008342(Dishevelled-3 protein, C-terminal)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:Q92997|rcsb pdb:6V7O|rcsb pdb:6ZC6|rcsb pdb:6ZC8|reactome:R-HSA-201681|reactome:R-HSA-201688|reactome:R-HSA-4086400|reactome:R-HSA-4641258|reactome:R-HSA-4641262|reactome:R-HSA-5368598|reactome:R-HSA-5663220|reactome:R-HSA-9673324|entrezgene/locuslink:1857(identity)	sgd:S000003115|refseq:NP_011368.3|ensemblfungi:YGL147C(gene)|ensemblfungi:YGL147C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0019843"(rRNA binding)|go:"GO:0022625"(cytosolic large ribosomal subunit)|interpro:IPR000702(Ribosomal protein L6)|interpro:IPR002359(Ribosomal protein L6, conserved site-2)|interpro:IPR020040|interpro:IPR036789|rcsb pdb:1K5Y|rcsb pdb:3J16|rcsb pdb:3J6X|rcsb pdb:3J6Y|rcsb pdb:3J77|rcsb pdb:3J78|rcsb pdb:3JCT|rcsb pdb:4U3M|rcsb pdb:4U3N|rcsb pdb:4U3U|rcsb pdb:4U4N|rcsb pdb:4U4O|rcsb pdb:4U4Q|rcsb pdb:4U4R|rcsb pdb:4U4U|rcsb pdb:4U4Y|rcsb pdb:4U4Z|rcsb pdb:4U50|rcsb pdb:4U51|rcsb pdb:4U52|rcsb pdb:4U53|rcsb pdb:4U55|rcsb pdb:4U56|rcsb pdb:4U6F|rcsb pdb:4V4B|rcsb pdb:4V6I|rcsb pdb:4V7F|rcsb pdb:4V7R|rcsb pdb:4V88|rcsb pdb:4V8T|rcsb pdb:4V8Y|rcsb pdb:7NRD|rcsb pdb:4V8Z|rcsb pdb:4V91|rcsb pdb:5APN|rcsb pdb:5APO|rcsb pdb:5DAT|rcsb pdb:5DC3|rcsb pdb:5DGE|rcsb pdb:5DGF|rcsb pdb:5DGV|rcsb pdb:5FCI|rcsb pdb:5FCJ|rcsb pdb:5FL8|rcsb pdb:5GAK|rcsb pdb:5H4P|rcsb pdb:5I4L|rcsb pdb:5JCS|rcsb pdb:5JUO|rcsb pdb:5JUP|rcsb pdb:5JUS|rcsb pdb:5JUT|rcsb pdb:5JUU|rcsb pdb:5LYB|rcsb pdb:5M1J|rcsb pdb:5MC6|rcsb pdb:5MEI|rcsb pdb:5NDG|rcsb pdb:5NDV|rcsb pdb:5NDW|rcsb pdb:5OBM|rcsb pdb:5ON6|rcsb pdb:5T62|rcsb pdb:5T6R|rcsb pdb:5TBW|rcsb pdb:5TGA|rcsb pdb:5TGM|rcsb pdb:5Z3G|rcsb pdb:6ELZ|rcsb pdb:6EM1|rcsb pdb:6EM5|rcsb pdb:6FT6|rcsb pdb:6GQ1|rcsb pdb:6GQB|rcsb pdb:6GQV|rcsb pdb:6HD7|rcsb pdb:6HHQ|rcsb pdb:6I7O|rcsb pdb:6M62|rcsb pdb:6N8J|rcsb pdb:6N8K|rcsb pdb:6N8L|rcsb pdb:6N8M|rcsb pdb:6N8N|rcsb pdb:6N8O|rcsb pdb:6OIG|rcsb pdb:6Q8Y|rcsb pdb:6QIK|rcsb pdb:6QT0|rcsb pdb:6QTZ|rcsb pdb:6R84|rcsb pdb:6R86|rcsb pdb:6R87|rcsb pdb:6RI5|rcsb pdb:6RZZ|rcsb pdb:6S05|rcsb pdb:6S47|rcsb pdb:6SNT|rcsb pdb:6SV4|rcsb pdb:6T4Q|rcsb pdb:6T7I|rcsb pdb:6T7T|rcsb pdb:6T83|rcsb pdb:6TB3|rcsb pdb:6TNU|rcsb pdb:6YLG|rcsb pdb:6YLH|rcsb pdb:6YLX|rcsb pdb:6YLY|rcsb pdb:6Z6J|rcsb pdb:6Z6K|rcsb pdb:7AZY|rcsb pdb:7B7D|rcsb pdb:7BT6|rcsb pdb:7BTB|rcsb pdb:7NRC|dip:DIP-4826N|sgd:YGL147C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:yJ3YIp5IhvKTQwa3bK5yTjNyqXk9606	rogid:TCDvdj9QlqdgRadKyIWG7ane1hw559292	intact-crc:0778CB3F17496249|rigid:zMFEPUFkowDpfM3kSMjbz6SoM/0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P05738	uniprotkb:O14641	intact:EBI-15439|uniprotkb:D6VU02|ensemblfungi:YGL147C	intact:EBI-740850|ensembl:ENSP00000005340|uniprotkb:Q53XM0|uniprotkb:D3DTN3	psi-mi:rl9a_yeast(display_long)|uniprotkb:RPL9A(gene name)|psi-mi:RPL9A(display_short)|uniprotkb:RPL9(gene name synonym)|uniprotkb:RPL8A(gene name synonym)|uniprotkb:L8(gene name synonym)|uniprotkb:YL11(gene name synonym)|uniprotkb:RP24(gene name synonym)|uniprotkb:YGL147C(locus name)|uniprotkb:Large ribosomal subunit protein uL6-A(gene name synonym)	psi-mi:dvl2_human(display_long)|uniprotkb:DSH homolog 2(gene name synonym)|uniprotkb:DVL2(gene name)|psi-mi:DVL2(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11538395|imex:IM-24995-1684	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003115|refseq:NP_011368.3|ensemblfungi:YGL147C(gene)|ensemblfungi:YGL147C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0019843"(rRNA binding)|go:"GO:0022625"(cytosolic large ribosomal subunit)|interpro:IPR000702(Ribosomal protein L6)|interpro:IPR002359(Ribosomal protein L6, conserved site-2)|interpro:IPR020040|interpro:IPR036789|rcsb pdb:1K5Y|rcsb pdb:3J16|rcsb pdb:3J6X|rcsb pdb:3J6Y|rcsb pdb:3J77|rcsb pdb:3J78|rcsb pdb:3JCT|rcsb pdb:4U3M|rcsb pdb:4U3N|rcsb pdb:4U3U|rcsb pdb:4U4N|rcsb pdb:4U4O|rcsb pdb:4U4Q|rcsb pdb:4U4R|rcsb pdb:4U4U|rcsb pdb:4U4Y|rcsb pdb:4U4Z|rcsb pdb:4U50|rcsb pdb:4U51|rcsb pdb:4U52|rcsb pdb:4U53|rcsb pdb:4U55|rcsb pdb:4U56|rcsb pdb:4U6F|rcsb pdb:4V4B|rcsb pdb:4V6I|rcsb pdb:4V7F|rcsb pdb:4V7R|rcsb pdb:4V88|rcsb pdb:4V8T|rcsb pdb:4V8Y|rcsb pdb:7NRD|rcsb pdb:4V8Z|rcsb pdb:4V91|rcsb pdb:5APN|rcsb pdb:5APO|rcsb pdb:5DAT|rcsb pdb:5DC3|rcsb pdb:5DGE|rcsb pdb:5DGF|rcsb pdb:5DGV|rcsb pdb:5FCI|rcsb pdb:5FCJ|rcsb pdb:5FL8|rcsb pdb:5GAK|rcsb pdb:5H4P|rcsb pdb:5I4L|rcsb pdb:5JCS|rcsb pdb:5JUO|rcsb pdb:5JUP|rcsb pdb:5JUS|rcsb pdb:5JUT|rcsb pdb:5JUU|rcsb pdb:5LYB|rcsb pdb:5M1J|rcsb pdb:5MC6|rcsb pdb:5MEI|rcsb pdb:5NDG|rcsb pdb:5NDV|rcsb pdb:5NDW|rcsb pdb:5OBM|rcsb pdb:5ON6|rcsb pdb:5T62|rcsb pdb:5T6R|rcsb pdb:5TBW|rcsb pdb:5TGA|rcsb pdb:5TGM|rcsb pdb:5Z3G|rcsb pdb:6ELZ|rcsb pdb:6EM1|rcsb pdb:6EM5|rcsb pdb:6FT6|rcsb pdb:6GQ1|rcsb pdb:6GQB|rcsb pdb:6GQV|rcsb pdb:6HD7|rcsb pdb:6HHQ|rcsb pdb:6I7O|rcsb pdb:6M62|rcsb pdb:6N8J|rcsb pdb:6N8K|rcsb pdb:6N8L|rcsb pdb:6N8M|rcsb pdb:6N8N|rcsb pdb:6N8O|rcsb pdb:6OIG|rcsb pdb:6Q8Y|rcsb pdb:6QIK|rcsb pdb:6QT0|rcsb pdb:6QTZ|rcsb pdb:6R84|rcsb pdb:6R86|rcsb pdb:6R87|rcsb pdb:6RI5|rcsb pdb:6RZZ|rcsb pdb:6S05|rcsb pdb:6S47|rcsb pdb:6SNT|rcsb pdb:6SV4|rcsb pdb:6T4Q|rcsb pdb:6T7I|rcsb pdb:6T7T|rcsb pdb:6T83|rcsb pdb:6TB3|rcsb pdb:6TNU|rcsb pdb:6YLG|rcsb pdb:6YLH|rcsb pdb:6YLX|rcsb pdb:6YLY|rcsb pdb:6Z6J|rcsb pdb:6Z6K|rcsb pdb:7AZY|rcsb pdb:7B7D|rcsb pdb:7BT6|rcsb pdb:7BTB|rcsb pdb:7NRC|dip:DIP-4826N|sgd:YGL147C(identity)	refseq:NP_004413.1|ensembl:ENSG00000004975(gene)|ensembl:ENST00000005340(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005109"(frizzled binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0007507"(heart development)|go:"GO:0016235"(aggresome)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044340"(canonical Wnt signaling pathway involved in regulation of cell proliferation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0150012"(positive regulation of neuron projection arborization)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008341(Dishevelled-2 region)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:O14641|rcsb pdb:2REY|rcsb pdb:3CBX|rcsb pdb:3CBY|rcsb pdb:3CBZ|rcsb pdb:3CC0|rcsb pdb:4WIP|rcsb pdb:5LNP|rcsb pdb:5SUY|rcsb pdb:5SUZ|rcsb pdb:6IW3|rcsb pdb:6JCK|reactome:R-HSA-201681|reactome:R-HSA-201688|reactome:R-HSA-2028269|reactome:R-HSA-4086400|reactome:R-HSA-4608870|reactome:R-HSA-4641258|reactome:R-HSA-4641262|reactome:R-HSA-5099900|reactome:R-HSA-5368598|reactome:R-HSA-5663220|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9673324|ensembl:ENSP00000005340|dip:DIP-34433N|entrezgene/locuslink:1856(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:TCDvdj9QlqdgRadKyIWG7ane1hw559292	rogid:2Vdc8oRnT4Mz/j+EXQXrL3AszOc9606	intact-crc:F20DC186398872C1|rigid:KqIOTMa/9fGdg3f2mHv0SPhCTw0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P06787	uniprotkb:O94983-5	intact:EBI-3976|uniprotkb:D6VQA8|ensemblfungi:YBR109C	intact:EBI-10176008	psi-mi:calm_yeast(display_long)|uniprotkb:YBR0904(orf name)|uniprotkb:YBR109C(locus name)|uniprotkb:CMD1(gene name)|psi-mi:CMD1(display_short)	psi-mi:o94983-5(display_long)|uniprotkb:KIAA0909(gene name synonym)|uniprotkb:CAMTA2(gene name)|psi-mi:CAMTA2(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11538503|imex:IM-24995-1696	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009667.1|sgd:S000000313|dip:DIP-536N|mint:P06787|ensemblfungi:YBR109C(gene)|ensemblfungi:YBR109C_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0000742"(karyogamy involved in conjugation with cellular fusion)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005823"(central plaque of spindle pole body)|go:"GO:0005933"(cellular bud)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0006897"(endocytosis)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007114"(cell budding)|go:"GO:0016237"(lysosomal microautophagy)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0042144"(vacuole fusion, non-autophagic)|go:"GO:0043332"(mating projection tip)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051019"(mitogen-activated protein kinase binding)|go:"GO:0051300"(spindle pole body organization)|go:"GO:1903525"(regulation of membrane tubulation)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR039030|rcsb pdb:1F54|rcsb pdb:1F55|rcsb pdb:1LKJ|rcsb pdb:2LHH|rcsb pdb:2LHI|rcsb pdb:6OQQ|reactome:R-SCE-111932|reactome:R-SCE-114608|reactome:R-SCE-1474151|reactome:R-SCE-203615|reactome:R-SCE-2871809|reactome:R-SCE-4086398|reactome:R-SCE-442729|reactome:R-SCE-5218920|reactome:R-SCE-5607763|reactome:R-SCE-5626467|reactome:R-SCE-6798695|reactome:R-SCE-9009391|reactome:R-SCE-9619229|sgd:YBR109C(identity)	intact:EBI-936534(isoform-parent)|uniprotkb:O94983-5(isoform-parent)|entrezgene/locuslink:23125(identity)	-	crc64:819ED1AD5D9400D3	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:jyNQ4XuG4o2uZi6ztTIMCcgbQFM559292	rogid:vzdEZ0CgkqevyH4Na04MPr4O6TM9606	intact-crc:EE18E3526A77C208|rigid:15hU7apRfQRdlXDSqgd2L1/aR6k	false	-	sufficient binding region:109-329	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UKT9	uniprotkb:P06782	intact:EBI-747204|uniprotkb:Q8WWQ9|uniprotkb:Q8WWR0|uniprotkb:Q8WWR1|uniprotkb:Q8WWR2|uniprotkb:Q8WWR3|uniprotkb:Q8N574|uniprotkb:B4DVV5|uniprotkb:Q69BL6|uniprotkb:Q69BL7|uniprotkb:Q69BL8|uniprotkb:Q69BL9|uniprotkb:Q69BM0|uniprotkb:Q69BM1|uniprotkb:Q69BM2|uniprotkb:Q69BM3|uniprotkb:Q69BM5|ensembl:ENSP00000344544	intact:EBI-17516|uniprotkb:D6VTA0|ensemblfungi:YDR477W	psi-mi:ikzf3_human(display_long)|uniprotkb:ZNFN1A3(gene name synonym)|uniprotkb:Ikaros family zinc finger protein 3(gene name synonym)|uniprotkb:IKZF3(gene name)|psi-mi:IKZF3(display_short)	psi-mi:snf1_yeast(display_long)|uniprotkb:SNF1(gene name)|psi-mi:SNF1(display_short)|uniprotkb:CAT1(gene name synonym)|uniprotkb:CCR1(gene name synonym)|uniprotkb:GLC2(gene name synonym)|uniprotkb:PAS14(gene name synonym)|uniprotkb:Sucrose nonfermentating protein 1(gene name synonym)|uniprotkb:D8035.20(orf name)|uniprotkb:YDR477W(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11538494|imex:IM-24995-1695	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001271443.1|refseq:NP_001271444.1|refseq:NP_036613.2|refseq:NP_899051.1|refseq:NP_899052.1|refseq:NP_899053.1|refseq:NP_899054.1|refseq:NP_899055.1|refseq:NP_001271445.1|refseq:NP_001244337.1|refseq:NP_001244338.1|refseq:NP_001244339.1|refseq:NP_001244340.1|refseq:NP_001244341.1|refseq:NP_001244342.1|refseq:NP_001244343.1|ensembl:ENSG00000161405(gene)|ensembl:ENST00000346872(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007498"(mesoderm development)|go:"GO:0009617"(response to bacterium)|go:"GO:0030888"(regulation of B cell proliferation)|go:"GO:0042113"(B cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045577"(regulation of B cell differentiation)|go:"GO:0045619"(regulation of lymphocyte differentiation)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|go:"GO:0046872"(metal ion binding)|dip:DIP-56975N|entrezgene/locuslink:22806(identity)	refseq:NP_010765.3|sgd:S000002885|ensemblfungi:YDR477W(gene)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0071940"(fungal-type cell wall assembly)|go:"GO:0090606"(single-species surface biofilm formation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900436"(positive regulation of filamentous growth of a population of unicellular organisms in response to starvation)|go:"GO:2000222"(positive regulation of pseudohyphal growth)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013896(Ubiquitin-associated region 2)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR028375|interpro:IPR032270|rcsb pdb:2FH9|rcsb pdb:2QLV|rcsb pdb:3DAE|rcsb pdb:3HYH|rcsb pdb:3MN3|rcsb pdb:3T4N|rcsb pdb:3TDH|rcsb pdb:3TE5|reactome:R-SCE-1632852|reactome:R-SCE-163680|reactome:R-SCE-200425|reactome:R-SCE-380972|ensemblfungi:YDR477W_mRNA(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000144"(cellular bud neck septin ring)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004679"(AMP-activated protein kinase activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005641"(nuclear envelope lumen)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0007155"(cell adhesion)|go:"GO:0016239"(positive regulation of macroautophagy)|dip:DIP-18N|mint:P06782|sgd:YDR477W(identity)	-	-	crc64:F5C63565C986C4E3	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:2Kp6LefSLfK5VIiE6DmQusFIfMY9606	rogid:O/SAW1kJE3fpoXPHGLG01i9RePs559292	intact-crc:EC51C4965F28286C|rigid:lqfFs/MV9M4ricnpIgL3cu1sG64	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9BQ66	uniprotkb:P06782	intact:EBI-739863|uniprotkb:A3KMC5|uniprotkb:Q495I0|ensembl:ENSP00000377582|ensembl:ENSP00000458979	intact:EBI-17516|uniprotkb:D6VTA0|ensemblfungi:YDR477W	psi-mi:kr412_human(display_long)|uniprotkb:KRTAP4-12(gene name)|psi-mi:KRTAP4-12(display_short)|uniprotkb:KAP4.12(gene name synonym)|uniprotkb:KRTAP4.12(gene name synonym)|uniprotkb:Keratin-associated protein 4.12(gene name synonym)|uniprotkb:Ultrahigh sulfur keratin-associated protein 4.12(gene name synonym)	psi-mi:snf1_yeast(display_long)|uniprotkb:SNF1(gene name)|psi-mi:SNF1(display_short)|uniprotkb:CAT1(gene name synonym)|uniprotkb:CCR1(gene name synonym)|uniprotkb:GLC2(gene name synonym)|uniprotkb:PAS14(gene name synonym)|uniprotkb:Sucrose nonfermentating protein 1(gene name synonym)|uniprotkb:D8035.20(orf name)|uniprotkb:YDR477W(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11538485|imex:IM-24995-1694	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_114060.1|ensembl:ENSG00000213416(gene)|ensembl:ENSG00000263236(gene)|ensembl:ENST00000394014(transcript)|ensembl:ENST00000571271(transcript)|go:"GO:0045095"(keratin filament)|interpro:IPR002494(Keratin, high sulphur B2 protein)|entrezgene/locuslink:83755(identity)	refseq:NP_010765.3|sgd:S000002885|ensemblfungi:YDR477W(gene)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0071940"(fungal-type cell wall assembly)|go:"GO:0090606"(single-species surface biofilm formation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900436"(positive regulation of filamentous growth of a population of unicellular organisms in response to starvation)|go:"GO:2000222"(positive regulation of pseudohyphal growth)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013896(Ubiquitin-associated region 2)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR028375|interpro:IPR032270|rcsb pdb:2FH9|rcsb pdb:2QLV|rcsb pdb:3DAE|rcsb pdb:3HYH|rcsb pdb:3MN3|rcsb pdb:3T4N|rcsb pdb:3TDH|rcsb pdb:3TE5|reactome:R-SCE-1632852|reactome:R-SCE-163680|reactome:R-SCE-200425|reactome:R-SCE-380972|ensemblfungi:YDR477W_mRNA(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000144"(cellular bud neck septin ring)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004679"(AMP-activated protein kinase activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005641"(nuclear envelope lumen)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0007155"(cell adhesion)|go:"GO:0016239"(positive regulation of macroautophagy)|dip:DIP-18N|mint:P06782|sgd:YDR477W(identity)	-	-	crc64:F5C63565C986C4E3	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:XLiYOwNd549kn287BJWgx5zmDCY9606	rogid:O/SAW1kJE3fpoXPHGLG01i9RePs559292	intact-crc:A11EE9EA256367C8|rigid:aFoJnKS6fhMQMaDuej7AMRvcy2c	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q99750	uniprotkb:P06782	intact:EBI-724076|ensembl:ENSP00000230321|ensembl:ENSP00000362142	intact:EBI-17516|uniprotkb:D6VTA0|ensemblfungi:YDR477W	psi-mi:mdfi_human(display_long)|uniprotkb:Myogenic repressor I-mf(gene name synonym)|uniprotkb:MDFI(gene name)|psi-mi:MDFI(display_short)	psi-mi:snf1_yeast(display_long)|uniprotkb:SNF1(gene name)|psi-mi:SNF1(display_short)|uniprotkb:CAT1(gene name synonym)|uniprotkb:CCR1(gene name synonym)|uniprotkb:GLC2(gene name synonym)|uniprotkb:PAS14(gene name synonym)|uniprotkb:Sucrose nonfermentating protein 1(gene name synonym)|uniprotkb:D8035.20(orf name)|uniprotkb:YDR477W(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11538476|imex:IM-24995-1693	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005577.1|ensembl:ENSG00000112559(gene)|ensembl:ENST00000230321(transcript)|ensembl:ENST00000373051(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR026134|mint:Q99750|refseq:NP_001287733.1|refseq:NP_001287734.1|refseq:NP_001287735.1|entrezgene/locuslink:4188(identity)	refseq:NP_010765.3|sgd:S000002885|ensemblfungi:YDR477W(gene)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0071940"(fungal-type cell wall assembly)|go:"GO:0090606"(single-species surface biofilm formation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900436"(positive regulation of filamentous growth of a population of unicellular organisms in response to starvation)|go:"GO:2000222"(positive regulation of pseudohyphal growth)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013896(Ubiquitin-associated region 2)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR028375|interpro:IPR032270|rcsb pdb:2FH9|rcsb pdb:2QLV|rcsb pdb:3DAE|rcsb pdb:3HYH|rcsb pdb:3MN3|rcsb pdb:3T4N|rcsb pdb:3TDH|rcsb pdb:3TE5|reactome:R-SCE-1632852|reactome:R-SCE-163680|reactome:R-SCE-200425|reactome:R-SCE-380972|ensemblfungi:YDR477W_mRNA(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000144"(cellular bud neck septin ring)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004679"(AMP-activated protein kinase activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005641"(nuclear envelope lumen)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0007155"(cell adhesion)|go:"GO:0016239"(positive regulation of macroautophagy)|dip:DIP-18N|mint:P06782|sgd:YDR477W(identity)	-	-	crc64:F5C63565C986C4E3	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:V3vU0fihMOW18DMHAiDbuZ3asNU9606	rogid:O/SAW1kJE3fpoXPHGLG01i9RePs559292	intact-crc:D341262CB8136B38|rigid:cSDwEv05Wb9pdoi2U44eYzMbaHM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P54619	uniprotkb:P06782	intact:EBI-1181439|ensembl:ENSP00000447433|uniprotkb:B4DDT7|uniprotkb:Q8N7V9	intact:EBI-17516|uniprotkb:D6VTA0|ensemblfungi:YDR477W	psi-mi:aakg1_human(display_long)|uniprotkb:PRKAG1(gene name)|psi-mi:PRKAG1(display_short)	psi-mi:snf1_yeast(display_long)|uniprotkb:SNF1(gene name)|psi-mi:SNF1(display_short)|uniprotkb:CAT1(gene name synonym)|uniprotkb:CCR1(gene name synonym)|uniprotkb:GLC2(gene name synonym)|uniprotkb:PAS14(gene name synonym)|uniprotkb:Sucrose nonfermentating protein 1(gene name synonym)|uniprotkb:D8035.20(orf name)|uniprotkb:YDR477W(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11538467|imex:IM-24995-1692	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001193638.1|refseq:NP_001193639.1|refseq:NP_002724.1|refseq:XP_011536864.1|reactome:R-HSA-9619483|reactome:R-HSA-9613354|ensembl:ENSG00000181929(gene)|ensembl:ENST00000548065(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004691"(cAMP-dependent protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006110"(regulation of glycolytic process)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008603"(cAMP-dependent protein kinase regulator activity)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016208"(AMP binding)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0043531"(ADP binding)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051170"(import into nucleus)|go:"GO:0071900"(regulation of protein serine/threonine kinase activity)|interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR039166|mint:P54619|rcsb pdb:2UV4|rcsb pdb:2UV5|rcsb pdb:2UV6|rcsb pdb:2UV7|rcsb pdb:4CFE|rcsb pdb:4CFF|rcsb pdb:4RER|rcsb pdb:4REW|rcsb pdb:4ZHX|rcsb pdb:5EZV|rcsb pdb:5ISO|rcsb pdb:6B1U|rcsb pdb:6B2E|rcsb pdb:6C9F|rcsb pdb:6C9G|rcsb pdb:6C9H|rcsb pdb:6C9J|reactome:R-HSA-1445148|reactome:R-HSA-1632852|reactome:R-HSA-2151209|reactome:R-HSA-380972|reactome:R-HSA-5628897|reactome:R-HSA-6804756|refseq:XP_006719562.1|dip:DIP-39974N|entrezgene/locuslink:5571(identity)	refseq:NP_010765.3|sgd:S000002885|ensemblfungi:YDR477W(gene)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0071940"(fungal-type cell wall assembly)|go:"GO:0090606"(single-species surface biofilm formation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900436"(positive regulation of filamentous growth of a population of unicellular organisms in response to starvation)|go:"GO:2000222"(positive regulation of pseudohyphal growth)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013896(Ubiquitin-associated region 2)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR028375|interpro:IPR032270|rcsb pdb:2FH9|rcsb pdb:2QLV|rcsb pdb:3DAE|rcsb pdb:3HYH|rcsb pdb:3MN3|rcsb pdb:3T4N|rcsb pdb:3TDH|rcsb pdb:3TE5|reactome:R-SCE-1632852|reactome:R-SCE-163680|reactome:R-SCE-200425|reactome:R-SCE-380972|ensemblfungi:YDR477W_mRNA(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000144"(cellular bud neck septin ring)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004679"(AMP-activated protein kinase activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005641"(nuclear envelope lumen)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0007155"(cell adhesion)|go:"GO:0016239"(positive regulation of macroautophagy)|dip:DIP-18N|mint:P06782|sgd:YDR477W(identity)	-	-	crc64:F5C63565C986C4E3	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:JNBzPdCbcgr37RKb2sk6yVL+7649606	rogid:O/SAW1kJE3fpoXPHGLG01i9RePs559292	intact-crc:865920BAA273C338|rigid:IgHiISYAnTxvf0XuRQBFtsbYGuE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P06782	uniprotkb:P14373	intact:EBI-17516|uniprotkb:D6VTA0|ensemblfungi:YDR477W	intact:EBI-719493|uniprotkb:A2BE15|uniprotkb:Q5RJA8|uniprotkb:Q5ST26|uniprotkb:Q6LA73|uniprotkb:Q6NXR9|uniprotkb:Q9BZY6|uniprotkb:Q9UJL3|ensembl:ENSP00000383555|ensembl:ENSP00000392787|ensembl:ENSP00000405229|ensembl:ENSP00000414793|ensembl:ENSP00000366404	psi-mi:snf1_yeast(display_long)|uniprotkb:SNF1(gene name)|psi-mi:SNF1(display_short)|uniprotkb:CAT1(gene name synonym)|uniprotkb:CCR1(gene name synonym)|uniprotkb:GLC2(gene name synonym)|uniprotkb:PAS14(gene name synonym)|uniprotkb:Sucrose nonfermentating protein 1(gene name synonym)|uniprotkb:D8035.20(orf name)|uniprotkb:YDR477W(locus name)	psi-mi:tri27_human(display_long)|uniprotkb:TRIM27(gene name)|psi-mi:TRIM27(display_short)|uniprotkb:RNF76(gene name synonym)|uniprotkb:RFP(gene name synonym)|uniprotkb:Ret finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 27(gene name synonym)|uniprotkb:RING finger protein 76(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM27(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11538458|imex:IM-24995-1691	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010765.3|sgd:S000002885|ensemblfungi:YDR477W(gene)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0071940"(fungal-type cell wall assembly)|go:"GO:0090606"(single-species surface biofilm formation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900436"(positive regulation of filamentous growth of a population of unicellular organisms in response to starvation)|go:"GO:2000222"(positive regulation of pseudohyphal growth)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013896(Ubiquitin-associated region 2)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR028375|interpro:IPR032270|rcsb pdb:2FH9|rcsb pdb:2QLV|rcsb pdb:3DAE|rcsb pdb:3HYH|rcsb pdb:3MN3|rcsb pdb:3T4N|rcsb pdb:3TDH|rcsb pdb:3TE5|reactome:R-SCE-1632852|reactome:R-SCE-163680|reactome:R-SCE-200425|reactome:R-SCE-380972|ensemblfungi:YDR477W_mRNA(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000144"(cellular bud neck septin ring)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004679"(AMP-activated protein kinase activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005641"(nuclear envelope lumen)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0007155"(cell adhesion)|go:"GO:0016239"(positive regulation of macroautophagy)|dip:DIP-18N|mint:P06782|sgd:YDR477W(identity)	refseq:NP_006501.1|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0090281"(negative regulation of calcium ion import)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR020457|interpro:IPR035791|interpro:IPR043136|mint:P14373|reactome:R-HSA-3232142|reactome:R-HSA-9635465|reactome:R-HSA-8948751|ensembl:ENSG00000204713(gene)|ensembl:ENSG00000215641(gene)|ensembl:ENSG00000229006(gene)|ensembl:ENSG00000234495(gene)|ensembl:ENSG00000237071(gene)|ensembl:ENST00000377199(transcript)|ensembl:ENST00000400720(transcript)|ensembl:ENST00000431123(transcript)|ensembl:ENST00000435528(transcript)|ensembl:ENST00000437160(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001650"(fibrillar center)|go:"GO:0002820"(negative regulation of adaptive immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|entrezgene/locuslink:5987(identity)	-	crc64:F5C63565C986C4E3	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:O/SAW1kJE3fpoXPHGLG01i9RePs559292	rogid:dsfH5OUghD8KSaTz1SFw9OYVTK49606	intact-crc:3F28BA44A0D42A0D|rigid:h7VfHQetYAIiUYbPMZSfzqd4VHM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P06782	uniprotkb:O43597	intact:EBI-17516|uniprotkb:D6VTA0|ensemblfungi:YDR477W	intact:EBI-742487|uniprotkb:Q5T6Z7|ensembl:ENSP00000366306|ensembl:ENSP00000366308|uniprotkb:B2R9J9	psi-mi:snf1_yeast(display_long)|uniprotkb:SNF1(gene name)|psi-mi:SNF1(display_short)|uniprotkb:CAT1(gene name synonym)|uniprotkb:CCR1(gene name synonym)|uniprotkb:GLC2(gene name synonym)|uniprotkb:PAS14(gene name synonym)|uniprotkb:Sucrose nonfermentating protein 1(gene name synonym)|uniprotkb:D8035.20(orf name)|uniprotkb:YDR477W(locus name)	psi-mi:spy2_human(display_long)|uniprotkb:SPRY2(gene name)|psi-mi:SPRY2(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11538449|imex:IM-24995-1690	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010765.3|sgd:S000002885|ensemblfungi:YDR477W(gene)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0071940"(fungal-type cell wall assembly)|go:"GO:0090606"(single-species surface biofilm formation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900436"(positive regulation of filamentous growth of a population of unicellular organisms in response to starvation)|go:"GO:2000222"(positive regulation of pseudohyphal growth)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013896(Ubiquitin-associated region 2)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR028375|interpro:IPR032270|rcsb pdb:2FH9|rcsb pdb:2QLV|rcsb pdb:3DAE|rcsb pdb:3HYH|rcsb pdb:3MN3|rcsb pdb:3T4N|rcsb pdb:3TDH|rcsb pdb:3TE5|reactome:R-SCE-1632852|reactome:R-SCE-163680|reactome:R-SCE-200425|reactome:R-SCE-380972|ensemblfungi:YDR477W_mRNA(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000144"(cellular bud neck septin ring)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004679"(AMP-activated protein kinase activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005641"(nuclear envelope lumen)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0007155"(cell adhesion)|go:"GO:0016239"(positive regulation of macroautophagy)|dip:DIP-18N|mint:P06782|sgd:YDR477W(identity)	refseq:NP_005833.1|rcsb pdb:5HL0|reactome:R-HSA-1295596|reactome:R-HSA-182971|rcsb pdb:5HKZ|ensembl:ENST00000377102(transcript)|ensembl:ENST00000377104(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|ensembl:ENSG00000136158(gene)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030291"(protein serine/threonine kinase inhibitor activity)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031345"(negative regulation of cell projection organization)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0032587"(ruffle membrane)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0045165"(cell fate commitment)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048513"(animal organ development)|go:"GO:0051387"(negative regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060437"(lung growth)|go:"GO:0060449"(bud elongation involved in lung branching)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:1900747"(negative regulation of vascular endothelial growth factor signaling pathway)|go:"GO:1902747"(negative regulation of lens fiber cell differentiation)|go:"GO:1990752"(microtubule end)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR007875(Sprouty)|interpro:IPR030780|mint:O43597|rcsb pdb:3BUM|rcsb pdb:3OB1|rcsb pdb:5HKY|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|refseq:NP_001305465.1|refseq:NP_001305466.1|refseq:NP_001305467.1|entrezgene/locuslink:10253(identity)	-	crc64:F5C63565C986C4E3	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:O/SAW1kJE3fpoXPHGLG01i9RePs559292	rogid:u1omauzisc6MdZlogMotUmtauSI9606	intact-crc:8D4D2861466D9644|rigid:/pIvrusIwTiKh0zizHtESKccyf0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P0CD91	uniprotkb:Q8N6L0	intact:EBI-3820350|uniprotkb:O74680|uniprotkb:P53386|uniprotkb:D6W4J2|ensemblfungi:YPR192W	intact:EBI-749265|uniprotkb:Q96MC3|ensembl:ENSP00000404220	psi-mi:aqy1_yeast(display_long)|uniprotkb:AQY1(gene name)|psi-mi:AQY1(display_short)|uniprotkb:AQY1-2(gene name synonym)|uniprotkb:P9677.5(orf name)|uniprotkb:YPR192W(locus name)	psi-mi:kash5_human(display_long)|uniprotkb:KASH5(gene name)|psi-mi:KASH5(display_short)|uniprotkb:CCDC155(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 155(gene name synonym)|uniprotkb:KASH domain-containing protein 5(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11538554|imex:IM-24995-1701	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR034294|refseq:NP_015518.1|sgd:S000006396|interpro:IPR023271|interpro:IPR000425(Major intrinsic protein)|interpro:IPR022357|ensemblfungi:YPR192W(gene)|ensemblfungi:YPR192W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006833"(water transport)|go:"GO:0015250"(water channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030437"(ascospore formation)|go:"GO:0055085"(transmembrane transport)|sgd:YPR192W(identity)	refseq:NP_653289.3|ensembl:ENSG00000161609(gene)|ensembl:ENST00000447857(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034397"(telomere localization)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051225"(spindle assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0090172"(microtubule cytoskeleton organization involved in homologous chromosome segregation)|go:"GO:0090220"(chromosome localization to nuclear envelope involved in homologous chromosome segregation)|go:"GO:0090619"(meiotic spindle pole)|interpro:IPR011992(EF-Hand type)|interpro:IPR028168|interpro:IPR028170|interpro:IPR039508|mint:Q8N6L0|rcsb pdb:6R2I|rcsb pdb:6WMF|entrezgene/locuslink:147872(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:SJZXHf9xXd6KcuK51HURax8JgsY559292	rogid:Wl9L7AcvDHCZuKjYLn8QgGIbZTc9606	intact-crc:8840D7845EF2C77C|rigid:nKqk8JDYCD82tNVDhnNg9XNSiyA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9NZL4	uniprotkb:P09435	intact:EBI-356763|uniprotkb:O95351|uniprotkb:Q6ZNU5|uniprotkb:B3KQP0|uniprotkb:B4DG11|ensembl:ENSP00000255631|ensembl:ENSP00000398244|ensembl:ENSP00000467574	intact:EBI-8611|uniprotkb:P18862|uniprotkb:D6VPS7|ensemblfungi:YBL075C	psi-mi:hpbp1_human(display_long)|uniprotkb:HSPBP1(gene name)|psi-mi:HSPBP1(display_short)|uniprotkb:HSPBP(gene name synonym)|uniprotkb:PP1845(orf name)|uniprotkb:Heat shock protein-binding protein 1(gene name synonym)|uniprotkb:Hsp70-interacting protein 1(gene name synonym)|uniprotkb:Hsp70-binding protein 2(gene name synonym)|uniprotkb:Hsp70-interacting protein 2(gene name synonym)	psi-mi:hsp73_yeast(display_long)|uniprotkb:YBL06.07(orf name)|uniprotkb:YBL0610(orf name)|uniprotkb:YBL075C(locus name)|uniprotkb:SSA3(gene name)|psi-mi:SSA3(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11538543|imex:IM-24995-1700	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001123578.1|refseq:NP_036399.3|ensembl:ENSG00000133265(gene)|ensembl:ENST00000255631(transcript)|ensembl:ENST00000433386(transcript)|ensembl:ENST00000587922(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006457"(protein folding)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013918(Nucleotide exchange factor Fes1)|interpro:IPR016024(Armadillo-type fold)|mint:Q9NZL4|rcsb pdb:1XQR|rcsb pdb:1XQS|refseq:NP_001284529.1|refseq:XP_016882033.1|entrezgene/locuslink:23640(identity)	refseq:NP_009478.1|sgd:S000000171|mint:P09435|dip:DIP-2266N|ensemblfungi:YBL075C(gene)|ensemblfungi:YBL075C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|sgd:YBL075C(identity)	-	-	crc64:F4B136759B7D4636	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2018/09/20	rogid:26Au2GesO5ysT/yhYX/0oOO9Md89606	rogid:u3ayjvFHnVNMMrDZdrB7NWaGzBg559292	intact-crc:A05E5605945366FA|rigid:dUh2qq010WSAE0IUFY/aCrP3YqM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P09435	uniprotkb:Q9NZL4	intact:EBI-8611|uniprotkb:P18862|uniprotkb:D6VPS7|ensemblfungi:YBL075C	intact:EBI-356763|uniprotkb:O95351|uniprotkb:Q6ZNU5|uniprotkb:B3KQP0|uniprotkb:B4DG11|ensembl:ENSP00000255631|ensembl:ENSP00000398244|ensembl:ENSP00000467574	psi-mi:hsp73_yeast(display_long)|uniprotkb:YBL06.07(orf name)|uniprotkb:YBL0610(orf name)|uniprotkb:YBL075C(locus name)|uniprotkb:SSA3(gene name)|psi-mi:SSA3(display_short)	psi-mi:hpbp1_human(display_long)|uniprotkb:HSPBP1(gene name)|psi-mi:HSPBP1(display_short)|uniprotkb:HSPBP(gene name synonym)|uniprotkb:PP1845(orf name)|uniprotkb:Heat shock protein-binding protein 1(gene name synonym)|uniprotkb:Hsp70-interacting protein 1(gene name synonym)|uniprotkb:Hsp70-binding protein 2(gene name synonym)|uniprotkb:Hsp70-interacting protein 2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11538534|imex:IM-24995-1699	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009478.1|sgd:S000000171|mint:P09435|dip:DIP-2266N|ensemblfungi:YBL075C(gene)|ensemblfungi:YBL075C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|sgd:YBL075C(identity)	refseq:NP_001123578.1|refseq:NP_036399.3|ensembl:ENSG00000133265(gene)|ensembl:ENST00000255631(transcript)|ensembl:ENST00000433386(transcript)|ensembl:ENST00000587922(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006457"(protein folding)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013918(Nucleotide exchange factor Fes1)|interpro:IPR016024(Armadillo-type fold)|mint:Q9NZL4|rcsb pdb:1XQR|rcsb pdb:1XQS|refseq:NP_001284529.1|refseq:XP_016882033.1|entrezgene/locuslink:23640(identity)	-	crc64:F4B136759B7D4636	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2018/09/18	rogid:u3ayjvFHnVNMMrDZdrB7NWaGzBg559292	rogid:26Au2GesO5ysT/yhYX/0oOO9Md89606	intact-crc:2FC38725DEC75D7C|rigid:dUh2qq010WSAE0IUFY/aCrP3YqM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P09201	uniprotkb:P09467	intact:EBI-6744|uniprotkb:D6VZ13|ensemblfungi:YLR377C	intact:EBI-712740|ensembl:ENSP00000364475|ensembl:ENSP00000408025|uniprotkb:O75571|uniprotkb:Q53F94|uniprotkb:Q96E46	psi-mi:f16p_yeast(display_long)|uniprotkb:FBP1(gene name)|psi-mi:FBP1(display_short)|uniprotkb:YLR377C(locus name)|uniprotkb:L8039.18(orf name)|uniprotkb:D-fructose-1,6-bisphosphate 1-phosphohydrolase(gene name synonym)	psi-mi:f16p1_human(display_long)|uniprotkb:D-fructose-1,6-bisphosphate 1-phosphohydrolase 1(gene name synonym)|uniprotkb:FBP1(gene name)|psi-mi:FBP1(display_short)|uniprotkb:FBP(gene name synonym)|uniprotkb:Liver FBPase(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11538525|imex:IM-24995-1698	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013481.3|sgd:S000004369|dip:DIP-3986N|mint:P09201|ensemblfungi:YLR377C(gene)|ensemblfungi:YLR377C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005986"(sucrose biosynthetic process)|go:"GO:0006000"(fructose metabolic process)|go:"GO:0006002"(fructose 6-phosphate metabolic process)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0030388"(fructose 1,6-bisphosphate metabolic process)|go:"GO:0042132"(fructose 1,6-bisphosphate 1-phosphatase activity)|go:"GO:0042597"(periplasmic space)|go:"GO:0046872"(metal ion binding)|go:"GO:0072593"(reactive oxygen species metabolic process)|interpro:IPR000146(Inositol phosphatase/fructose-1,6-bisphosphatase)|interpro:IPR020548|interpro:IPR028343|interpro:IPR033391|interpro:IPR044015|rcsb pdb:7NS5|reactome:R-SCE-70263|sgd:YLR377C(identity)	ensembl:ENST00000375326(transcript)|ensembl:ENST00000415431(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005986"(sucrose biosynthetic process)|go:"GO:0006000"(fructose metabolic process)|go:"GO:0006002"(fructose 6-phosphate metabolic process)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006111"(regulation of gluconeogenesis)|go:"GO:0016208"(AMP binding)|go:"GO:0016311"(dephosphorylation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030388"(fructose 1,6-bisphosphate metabolic process)|go:"GO:0035690"|go:"GO:0042132"(fructose 1,6-bisphosphate 1-phosphatase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0045820"(negative regulation of glycolytic process)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0046872"(metal ion binding)|go:"GO:0048029"(monosaccharide binding)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071286"(cellular response to magnesium ion)|interpro:IPR000146(Inositol phosphatase/fructose-1,6-bisphosphatase)|interpro:IPR020548|interpro:IPR028343|interpro:IPR033391|interpro:IPR044015|mint:P09467|rcsb pdb:1FTA|rcsb pdb:2FHY|rcsb pdb:2FIE|rcsb pdb:2FIX|rcsb pdb:2JJK|rcsb pdb:2VT5|rcsb pdb:2WBB|rcsb pdb:2WBD|rcsb pdb:2Y5K|rcsb pdb:2Y5L|rcsb pdb:3A29|rcsb pdb:3KBZ|rcsb pdb:3KC0|ensembl:ENSG00000165140(gene)|rcsb pdb:3KC1|rcsb pdb:4MJO|rcsb pdb:5LDZ|rcsb pdb:5PZR|rcsb pdb:5PZS|rcsb pdb:5PZT|rcsb pdb:5PZU|rcsb pdb:5PZV|rcsb pdb:5PZW|rcsb pdb:5PZX|rcsb pdb:5PZY|rcsb pdb:5PZZ|rcsb pdb:5Q00|rcsb pdb:5Q01|rcsb pdb:5Q02|rcsb pdb:5Q03|rcsb pdb:5Q04|rcsb pdb:5Q05|rcsb pdb:5Q06|rcsb pdb:5Q07|rcsb pdb:5Q08|rcsb pdb:5Q09|rcsb pdb:5PZQ|rcsb pdb:5Q0A|rcsb pdb:5Q0B|rcsb pdb:6LS5|rcsb pdb:6LW2|rcsb pdb:7C9Q|rcsb pdb:7CVN|reactome:R-HSA-70263|refseq:NP_000498.2|refseq:NP_001121100.1|dip:DIP-46677N|entrezgene/locuslink:2203(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:hvvSZcZrdcN9FcOmFzY/jCYIcJY559292	rogid:DnrtyrU5WL/7ut1qWv7LndveJT89606	intact-crc:B1C172E195607D01|rigid:/hmm1xVCnVzWSAVYiTg4jul4030	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P08458	uniprotkb:Q9NWX6	intact:EBI-17889|uniprotkb:D6VTE3|ensemblfungi:YDR523C	intact:EBI-746510|uniprotkb:Q53G12|uniprotkb:Q7L5R3|uniprotkb:Q9H0S2|uniprotkb:D3DQJ5|ensembl:ENSP00000231198	psi-mi:sps1_yeast(display_long)|uniprotkb:D9719.27(orf name)|uniprotkb:YDR523C(locus name)|uniprotkb:SPS1(gene name)|psi-mi:SPS1(display_short)	psi-mi:thg1_human(display_long)|uniprotkb:Induced in high glucose-1(gene name synonym)|uniprotkb:tRNA-histidine guanylyltransferase(gene name synonym)|uniprotkb:Interphase cytoplasmic foci protein 45(gene name synonym)|uniprotkb:THG1L(gene name)|psi-mi:THG1L(display_short)|uniprotkb:ICF45(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11538514|imex:IM-24995-1697	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010811.1|sgd:S000002931|ensemblfungi:YDR523C(gene)|ensemblfungi:YDR523C_mRNA(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005628"(prospore membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0030437"(ascospore formation)|go:"GO:0030476"(ascospore wall assembly)|go:"GO:0051229"(meiotic spindle disassembly)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903024"(positive regulation of ascospore-type prospore membrane formation)|go:"GO:1904750"(negative regulation of protein localization to nucleolus)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|dip:DIP-6598N|mint:P08458|sgd:YDR523C(identity)	refseq:NP_001304753.1|refseq:NP_001304754.1|refseq:NP_001304755.1|refseq:NP_060342.2|ensembl:ENSG00000113272(gene)|ensembl:ENST00000231198(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006400"(tRNA modification)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008033"(tRNA processing)|go:"GO:0008053"(mitochondrial fusion)|go:"GO:0008193"(tRNA guanylyltransferase activity)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0051289"(protein homotetramerization)|go:"GO:1990046"(stress-induced mitochondrial fusion)|go:"GO:1990234"(transferase complex)|interpro:IPR007537(tRNAHis guanylyltransferase)|interpro:IPR024956|interpro:IPR025845|interpro:IPR038469|rcsb pdb:3OTB|rcsb pdb:3OTC|rcsb pdb:3OTD|rcsb pdb:3OTE|rcsb pdb:7CV1|reactome:R-HSA-6782315|dip:DIP-59479N|entrezgene/locuslink:54974(identity)	-	crc64:6143055E85BAF4FF	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:icg6ZPlLWE0X6aii9Onq9FVzOuM559292	rogid:P1Q3muoqX06qZw9Xu0Gz5f8ALv49606	intact-crc:7F9A0B38574C78D6|rigid:SrDa8HKNeMAkeD8LtzmHv59JIFQ	false	-	sufficient binding region:30-298	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P10659	uniprotkb:P31153	intact:EBI-10789|ensemblfungi:YLR180W|uniprotkb:D6VYI4	intact:EBI-1050743|uniprotkb:Q53SP5|uniprotkb:A8K511|uniprotkb:D6W5L1|ensembl:ENSP00000303147|uniprotkb:B4DN45	psi-mi:metk1_yeast(display_long)|uniprotkb:SAM1(gene name)|psi-mi:SAM1(display_short)|uniprotkb:ETH10(gene name synonym)|uniprotkb:YLR180W(locus name)|uniprotkb:L9470.9(orf name)|uniprotkb:Methionine adenosyltransferase 1(gene name synonym)	psi-mi:metk2_human(display_long)|uniprotkb:Methionine adenosyltransferase 2(gene name synonym)|uniprotkb:Methionine adenosyltransferase II(gene name synonym)|uniprotkb:MAT2A(gene name)|psi-mi:MAT2A(display_short)|uniprotkb:AMS2(gene name synonym)|uniprotkb:MATA2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11538610|imex:IM-24995-1707	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YLR180W(gene)|ensemblfungi:YLR180W_mRNA(transcript)|go:"GO:0004478"(methionine adenosyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006555"(methionine metabolic process)|go:"GO:0006556"(S-adenosylmethionine biosynthetic process)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0046872"(metal ion binding)|interpro:IPR002133(S-adenosylmethionine synthetase)|interpro:IPR022628|interpro:IPR022629|interpro:IPR022630|interpro:IPR022631|interpro:IPR022636|reactome:R-SCE-156581|reactome:R-SCE-1614635|reactome:R-SCE-2408508|refseq:NP_013281.1|sgd:S000004170|mint:P10659|dip:DIP-6667N|sgd:YLR180W(identity)	refseq:NP_005902.1|rcsb pdb:5A1G|rcsb pdb:5A1I|rcsb pdb:5UGH|rcsb pdb:6FAJ|rcsb pdb:6FBN|rcsb pdb:6FBO|rcsb pdb:6FBP|rcsb pdb:6FCB|rcsb pdb:6FCD|rcsb pdb:6FWB|ensembl:ENSG00000168906(gene)|ensembl:ENST00000306434(transcript)|go:"GO:0004478"(methionine adenosyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006556"(S-adenosylmethionine biosynthetic process)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0034214"(protein hexamerization)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048269"(methionine adenosyltransferase complex)|go:"GO:0051291"(protein heterooligomerization)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR002133(S-adenosylmethionine synthetase)|rcsb pdb:6G6R|rcsb pdb:6P9V|rcsb pdb:6WKB|interpro:IPR022628|rcsb pdb:7BHR|rcsb pdb:7BHS|interpro:IPR022629|interpro:IPR022630|interpro:IPR022631|interpro:IPR022636|mint:P31153|rcsb pdb:2P02|rcsb pdb:4KTT|rcsb pdb:4KTV|rcsb pdb:4NDN|rcsb pdb:5A19|rcsb pdb:7BHT|rcsb pdb:7BHU|rcsb pdb:7BHV|rcsb pdb:7BHW|rcsb pdb:7BHX|rcsb pdb:7KCC|rcsb pdb:7KCE|rcsb pdb:7KCF|rcsb pdb:7KDA|rcsb pdb:7KDB|rcsb pdb:7L1A|reactome:R-HSA-156581|entrezgene/locuslink:4144(identity)	-	crc64:18F82FC809EE4706	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:PmIeDsMIksGSxihwmK1DqLFOItc559292	rogid:8QDKkbuHcvQtfzy2XkVjCKjTK709606	intact-crc:A531A2C6E6ACAFA1|rigid:CosvTDA0SKTdkrPi4EY0Y/z7Dm0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P10507	uniprotkb:Q96IK5	intact:EBI-11212|uniprotkb:D6VYG9|ensemblfungi:YLR163C	intact:EBI-2548508|ensembl:ENSP00000282570|uniprotkb:Q9H826|uniprotkb:Q9H8V7|uniprotkb:Q9H927	psi-mi:mppb_yeast(display_long)|uniprotkb:MAS1(gene name)|psi-mi:MAS1(display_short)|uniprotkb:MIF1(gene name synonym)|uniprotkb:Beta-MPP(gene name synonym)|uniprotkb:Mitochondrial assembly protein 1(gene name synonym)|uniprotkb:Processing enhancing protein(gene name synonym)|uniprotkb:L9632.10(orf name)|uniprotkb:YLR163C(locus name)	psi-mi:gmcl1_human(display_long)|uniprotkb:GMCL1(gene name)|psi-mi:GMCL1(display_short)|uniprotkb:GCL(gene name synonym)|uniprotkb:BTBD13(gene name synonym)|uniprotkb:SPATA29(gene name synonym)|uniprotkb:Spermatogenesis-associated protein 29(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11538601|imex:IM-24995-1706	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:1HR8|rcsb pdb:1HR9|reactome:R-SCE-611105|ensemblfungi:YLR163C_mRNA(transcript)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006627"(protein processing involved in protein targeting to mitochondrion)|go:"GO:0017087"(mitochondrial processing peptidase complex)|go:"GO:0046872"(metal ion binding)|interpro:IPR001431(Peptidase M16, zinc-binding site)|interpro:IPR007863(Peptidase M16, C-terminal)|interpro:IPR011249(Metalloenzyme, LuxS/M16 peptidase-like, metal-binding)|interpro:IPR011765(Peptidase M16, N-terminal)|rcsb pdb:1HR6|rcsb pdb:1HR7|ensemblfungi:YLR163C(gene)|refseq:NP_013264.1|sgd:S000004153|mint:P10507|dip:DIP-2402N|sgd:YLR163C(identity)	ensembl:ENSG00000087338(gene)|ensembl:ENST00000282570(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0007281"(germ cell development)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016363"(nuclear matrix)|go:"GO:0042802"(identical protein binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR043380|refseq:NP_848526.1|entrezgene/locuslink:64395(identity)	-	crc64:084CE63C495EDFC4	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:VwOYuBlWEvXC631d5WAhOhjVAPc559292	rogid:ED8yqySVu7BWxpw3DUSNBZSQWrk9606	intact-crc:BD7447D998043B52|rigid:kUmOXYm7g25dCm8NYfT0YIStVMA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8WTU0	uniprotkb:P10507	intact:EBI-748248|uniprotkb:Q7Z4U6|uniprotkb:Q8WTS3|ensembl:ENSP00000302805	intact:EBI-11212|uniprotkb:D6VYG9|ensemblfungi:YLR163C	psi-mi:ddi1_human(display_long)|uniprotkb:DDI1(gene name)|psi-mi:DDI1(display_short)	psi-mi:mppb_yeast(display_long)|uniprotkb:MAS1(gene name)|psi-mi:MAS1(display_short)|uniprotkb:MIF1(gene name synonym)|uniprotkb:Beta-MPP(gene name synonym)|uniprotkb:Mitochondrial assembly protein 1(gene name synonym)|uniprotkb:Processing enhancing protein(gene name synonym)|uniprotkb:L9632.10(orf name)|uniprotkb:YLR163C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11538592|imex:IM-24995-1705	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001001711.1|interpro:IPR000626(Ubiquitin)|interpro:IPR019103|interpro:IPR021109|interpro:IPR029071|interpro:IPR033882|rcsb pdb:3S8I|go:"GO:0097752"(regulation of DNA stability)|ensembl:ENSG00000170967(gene)|ensembl:ENST00000302259(transcript)|go:"GO:0004190"(aspartic-type endopeptidase activity)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0072711"(cellular response to hydroxyurea)|dip:DIP-60626N|entrezgene/locuslink:414301(identity)	rcsb pdb:1HR8|rcsb pdb:1HR9|reactome:R-SCE-611105|ensemblfungi:YLR163C_mRNA(transcript)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006627"(protein processing involved in protein targeting to mitochondrion)|go:"GO:0017087"(mitochondrial processing peptidase complex)|go:"GO:0046872"(metal ion binding)|interpro:IPR001431(Peptidase M16, zinc-binding site)|interpro:IPR007863(Peptidase M16, C-terminal)|interpro:IPR011249(Metalloenzyme, LuxS/M16 peptidase-like, metal-binding)|interpro:IPR011765(Peptidase M16, N-terminal)|rcsb pdb:1HR6|rcsb pdb:1HR7|ensemblfungi:YLR163C(gene)|refseq:NP_013264.1|sgd:S000004153|mint:P10507|dip:DIP-2402N|sgd:YLR163C(identity)	-	-	crc64:084CE63C495EDFC4	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:000xGRvL5rBRHv7/sbuzB7i7Wtc9606	rogid:VwOYuBlWEvXC631d5WAhOhjVAPc559292	intact-crc:828BF357E9EF4FD2|rigid:jpx1gdbg9ahPZ4bWDn5eNL6p70k	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q15038	uniprotkb:P0CH08	intact:EBI-724310|ensembl:ENSP00000394699|uniprotkb:E9PB45|uniprotkb:A8K254|uniprotkb:B4DDT5|uniprotkb:C9JA96|uniprotkb:C9JP84|uniprotkb:B4E1G3|uniprotkb:F8VU62	intact:EBI-11523108|uniprotkb:D6VVD9|uniprotkb:P04838|uniprotkb:P14796|uniprotkb:P61864|uniprotkb:Q6LA96|ensemblfungi:YIL148W|ensemblfungi:YKR094C	psi-mi:dazp2_human(display_long)|uniprotkb:Deleted in azoospermia-associated protein 2(gene name synonym)|uniprotkb:DAZAP2(gene name)|psi-mi:DAZAP2(display_short)|uniprotkb:KIAA0058(gene name synonym)	psi-mi:rl40a_yeast(display_long)|uniprotkb:RPL40A(gene name)|psi-mi:RPL40A(display_short)|uniprotkb:UBI1(gene name synonym)|uniprotkb:YIL148W(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11538583|imex:IM-24995-1704	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000183283(gene)|ensembl:ENST00000412716(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0016607"(nuclear speck)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0050699"(WW domain binding)|interpro:IPR022730|mint:Q15038|refseq:NP_001129736.1|refseq:NP_055579.1|ensembl:ENSP00000394699|ensembl:ENST00000425012|ensembl:ENSP00000408251|ensembl:ENST00000439799|ensembl:ENSP00000398804|ensembl:ENST00000449723|ensembl:ENSP00000412812|ensembl:ENST00000549555|ensembl:ENSP00000448051|ensembl:ENST00000549732|ensembl:ENSP00000446554|refseq:NP_001129741.1|refseq:NP_001129739.1|refseq:NP_001129740.1|refseq:NP_001129738.1|entrezgene/locuslink:9802(identity)	rcsb pdb:5NDG|rcsb pdb:5NDV|rcsb pdb:5NDW|rcsb pdb:5OBM|rcsb pdb:6WOO|interpro:IPR000626(Ubiquitin)|interpro:IPR001975(Ribosomal protein L40e)|interpro:IPR019954|interpro:IPR019956|interpro:IPR029071|rcsb pdb:3J6X|rcsb pdb:3J6Y|rcsb pdb:3J77|rcsb pdb:3J78|rcsb pdb:4U3M|rcsb pdb:4U3N|rcsb pdb:4U3U|rcsb pdb:4U4N|rcsb pdb:4U4O|rcsb pdb:4U4Q|rcsb pdb:4U4R|rcsb pdb:4U4U|rcsb pdb:4U4Y|rcsb pdb:4U4Z|rcsb pdb:4U50|rcsb pdb:4U51|rcsb pdb:4U52|rcsb pdb:4U53|rcsb pdb:4U55|rcsb pdb:4U56|rcsb pdb:4U6F|rcsb pdb:4V6I|rcsb pdb:4V88|rcsb pdb:4V8T|rcsb pdb:4V8Y|rcsb pdb:4V8Z|rcsb pdb:5APN|rcsb pdb:5APO|refseq:NP_012118.1|refseq:NP_013020.3|sgd:S000001410|rcsb pdb:6TB3|rcsb pdb:6TNU|rcsb pdb:5DGE|rcsb pdb:5M1J|rcsb pdb:5MC6|rcsb pdb:5TGM|rcsb pdb:6EF3|rcsb pdb:6OIG|rcsb pdb:6OA9|rcsb pdb:6OAA|rcsb pdb:6QIK|rcsb pdb:6QT0|rcsb pdb:6QTZ|rcsb pdb:6R84|rcsb pdb:6R87|rcsb pdb:6RI5|rcsb pdb:5FCI|rcsb pdb:5FCJ|rcsb pdb:5DGF|rcsb pdb:5DGV|rcsb pdb:5LYB|rcsb pdb:5TGA|rcsb pdb:6HHQ|rcsb pdb:5DC3|rcsb pdb:5I4L|rcsb pdb:6N8M|rcsb pdb:6N8N|rcsb pdb:6N8O|rcsb pdb:6I7O|rcsb pdb:7AZY|rcsb pdb:7B7D|rcsb pdb:7NRC|rcsb pdb:7NRD|reactome:R-SCE-1169408|reactome:R-SCE-5656169|rcsb pdb:5GAK|rcsb pdb:6Q8Y|ensemblfungi:YIL148W(gene)|ensemblfungi:YIL148W_mRNA(transcript)|ensemblfungi:YKR094C(gene)|ensemblfungi:YKR094C_mRNA(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0031386"(protein tag)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042254"(ribosome biogenesis)|rcsb pdb:6HD7|rcsb pdb:5ON6|rcsb pdb:5DAT|rcsb pdb:5JUO|rcsb pdb:5JUP|rcsb pdb:5JUS|rcsb pdb:5JUT|rcsb pdb:5JUU|rcsb pdb:5T62|rcsb pdb:5T6R|interpro:IPR038587|rcsb pdb:5MEI|rcsb pdb:5TBW|rcsb pdb:6GQ1|rcsb pdb:6GQB|rcsb pdb:6GQV|rcsb pdb:6R86|rcsb pdb:6S47|rcsb pdb:6NYO|rcsb pdb:6T4Q|rcsb pdb:6T7I|rcsb pdb:6T7T|rcsb pdb:6T83|rcsb pdb:6SNT|rcsb pdb:6SV4|rcsb pdb:6XIQ|rcsb pdb:6Z6J|rcsb pdb:6Z6K|sgd:YKR094C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/03/16	rogid:ASRqCZBG4q1U/y95PUSMKsgfm/g9606	rogid:6+5uVAktIpS9HyPHQ6BzXEuT/y0559292	intact-crc:009098FD7E732768|rigid:Lh/mIxvSJnpc6qjoQ5u0j8lqgrA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P0CH08	uniprotkb:Q13137	intact:EBI-11523108|uniprotkb:D6VVD9|uniprotkb:P04838|uniprotkb:P14796|uniprotkb:P61864|uniprotkb:Q6LA96|ensemblfungi:YIL148W|ensemblfungi:YKR094C	intact:EBI-739580|uniprotkb:B4DDC4|uniprotkb:E7ENK0|uniprotkb:Q53FQ5|uniprotkb:Q53HB5|uniprotkb:Q6IBN9|uniprotkb:Q9BTF7|uniprotkb:B2RBT0|ensembl:ENSP00000258947|uniprotkb:B4E0C0|uniprotkb:E7ETP5|uniprotkb:B4DDT4|uniprotkb:B4DP36|uniprotkb:E9PBE5	psi-mi:rl40a_yeast(display_long)|uniprotkb:RPL40A(gene name)|psi-mi:RPL40A(display_short)|uniprotkb:UBI1(gene name synonym)|uniprotkb:YIL148W(locus name)	psi-mi:caco2_human(display_long)|uniprotkb:CALCOCO2(gene name)|psi-mi:CALCOCO2(display_short)|uniprotkb:NDP52(gene name synonym)|uniprotkb:Nuclear domain 10 protein NDP52(gene name synonym)|uniprotkb:Antigen nuclear dot 52 kDa protein(gene name synonym)|uniprotkb:Nuclear dot protein 52(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11538574|imex:IM-24995-1703	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:5NDG|rcsb pdb:5NDV|rcsb pdb:5NDW|rcsb pdb:5OBM|rcsb pdb:6WOO|interpro:IPR000626(Ubiquitin)|interpro:IPR001975(Ribosomal protein L40e)|interpro:IPR019954|interpro:IPR019956|interpro:IPR029071|rcsb pdb:3J6X|rcsb pdb:3J6Y|rcsb pdb:3J77|rcsb pdb:3J78|rcsb pdb:4U3M|rcsb pdb:4U3N|rcsb pdb:4U3U|rcsb pdb:4U4N|rcsb pdb:4U4O|rcsb pdb:4U4Q|rcsb pdb:4U4R|rcsb pdb:4U4U|rcsb pdb:4U4Y|rcsb pdb:4U4Z|rcsb pdb:4U50|rcsb pdb:4U51|rcsb pdb:4U52|rcsb pdb:4U53|rcsb pdb:4U55|rcsb pdb:4U56|rcsb pdb:4U6F|rcsb pdb:4V6I|rcsb pdb:4V88|rcsb pdb:4V8T|rcsb pdb:4V8Y|rcsb pdb:4V8Z|rcsb pdb:5APN|rcsb pdb:5APO|refseq:NP_012118.1|refseq:NP_013020.3|sgd:S000001410|rcsb pdb:6TB3|rcsb pdb:6TNU|rcsb pdb:5DGE|rcsb pdb:5M1J|rcsb pdb:5MC6|rcsb pdb:5TGM|rcsb pdb:6EF3|rcsb pdb:6OIG|rcsb pdb:6OA9|rcsb pdb:6OAA|rcsb pdb:6QIK|rcsb pdb:6QT0|rcsb pdb:6QTZ|rcsb pdb:6R84|rcsb pdb:6R87|rcsb pdb:6RI5|rcsb pdb:5FCI|rcsb pdb:5FCJ|rcsb pdb:5DGF|rcsb pdb:5DGV|rcsb pdb:5LYB|rcsb pdb:5TGA|rcsb pdb:6HHQ|rcsb pdb:5DC3|rcsb pdb:5I4L|rcsb pdb:6N8M|rcsb pdb:6N8N|rcsb pdb:6N8O|rcsb pdb:6I7O|rcsb pdb:7AZY|rcsb pdb:7B7D|rcsb pdb:7NRC|rcsb pdb:7NRD|reactome:R-SCE-1169408|reactome:R-SCE-5656169|rcsb pdb:5GAK|rcsb pdb:6Q8Y|ensemblfungi:YIL148W(gene)|ensemblfungi:YIL148W_mRNA(transcript)|ensemblfungi:YKR094C(gene)|ensemblfungi:YKR094C_mRNA(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0031386"(protein tag)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042254"(ribosome biogenesis)|rcsb pdb:6HD7|rcsb pdb:5ON6|rcsb pdb:5DAT|rcsb pdb:5JUO|rcsb pdb:5JUP|rcsb pdb:5JUS|rcsb pdb:5JUT|rcsb pdb:5JUU|rcsb pdb:5T62|rcsb pdb:5T6R|interpro:IPR038587|rcsb pdb:5MEI|rcsb pdb:5TBW|rcsb pdb:6GQ1|rcsb pdb:6GQB|rcsb pdb:6GQV|rcsb pdb:6R86|rcsb pdb:6S47|rcsb pdb:6NYO|rcsb pdb:6T4Q|rcsb pdb:6T7I|rcsb pdb:6T7T|rcsb pdb:6T83|rcsb pdb:6SNT|rcsb pdb:6SV4|rcsb pdb:6XIQ|rcsb pdb:6Z6J|rcsb pdb:6Z6K|sgd:YKR094C(identity)	refseq:NP_001248319.1|refseq:NP_001248320.1|refseq:NP_001248322.1|refseq:NP_005822.1|ensembl:ENSG00000136436(gene)|ensembl:ENST00000258947(transcript)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016032"(viral process)|go:"GO:0016605"(PML body)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0098792"(xenophagy)|go:"GO:1901098"(positive regulation of autophagosome maturation)|interpro:IPR041611|interpro:IPR041641|mint:Q13137|rcsb pdb:2MXP|rcsb pdb:3VVV|rcsb pdb:3VVW|rcsb pdb:4GXL|rcsb pdb:4HAN|rcsb pdb:4XKL|rcsb pdb:5AAQ|rcsb pdb:5Z7A|rcsb pdb:5Z7L|refseq:NP_001248324.1|dip:DIP-57534N|entrezgene/locuslink:10241(identity)	-	-	crc64:609B121DA1A9DCB8	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/03/16	rogid:6+5uVAktIpS9HyPHQ6BzXEuT/y0559292	rogid:N/GPJUGBK+Dh5Cg+csmafphuo9M9606	intact-crc:DCAE9F16ADEE4A59|rigid:5MdELz9eh+rq5yMhwoRRG8yaiP4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P0CH08	uniprotkb:E9PFK9	intact:EBI-11523108|uniprotkb:D6VVD9|uniprotkb:P04838|uniprotkb:P14796|uniprotkb:P61864|uniprotkb:Q6LA96|ensemblfungi:YIL148W|ensemblfungi:YKR094C	intact:EBI-11523104|ensembl:ENSP00000403429	psi-mi:rl40a_yeast(display_long)|uniprotkb:RPL40A(gene name)|psi-mi:RPL40A(display_short)|uniprotkb:UBI1(gene name synonym)|uniprotkb:YIL148W(locus name)	psi-mi:e9pfk9_human(display_long)|uniprotkb:RABGEF1(gene name)|psi-mi:RABGEF1(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11538563|imex:IM-24995-1702	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:5NDG|rcsb pdb:5NDV|rcsb pdb:5NDW|rcsb pdb:5OBM|rcsb pdb:6WOO|interpro:IPR000626(Ubiquitin)|interpro:IPR001975(Ribosomal protein L40e)|interpro:IPR019954|interpro:IPR019956|interpro:IPR029071|rcsb pdb:3J6X|rcsb pdb:3J6Y|rcsb pdb:3J77|rcsb pdb:3J78|rcsb pdb:4U3M|rcsb pdb:4U3N|rcsb pdb:4U3U|rcsb pdb:4U4N|rcsb pdb:4U4O|rcsb pdb:4U4Q|rcsb pdb:4U4R|rcsb pdb:4U4U|rcsb pdb:4U4Y|rcsb pdb:4U4Z|rcsb pdb:4U50|rcsb pdb:4U51|rcsb pdb:4U52|rcsb pdb:4U53|rcsb pdb:4U55|rcsb pdb:4U56|rcsb pdb:4U6F|rcsb pdb:4V6I|rcsb pdb:4V88|rcsb pdb:4V8T|rcsb pdb:4V8Y|rcsb pdb:4V8Z|rcsb pdb:5APN|rcsb pdb:5APO|refseq:NP_012118.1|refseq:NP_013020.3|sgd:S000001410|rcsb pdb:6TB3|rcsb pdb:6TNU|rcsb pdb:5DGE|rcsb pdb:5M1J|rcsb pdb:5MC6|rcsb pdb:5TGM|rcsb pdb:6EF3|rcsb pdb:6OIG|rcsb pdb:6OA9|rcsb pdb:6OAA|rcsb pdb:6QIK|rcsb pdb:6QT0|rcsb pdb:6QTZ|rcsb pdb:6R84|rcsb pdb:6R87|rcsb pdb:6RI5|rcsb pdb:5FCI|rcsb pdb:5FCJ|rcsb pdb:5DGF|rcsb pdb:5DGV|rcsb pdb:5LYB|rcsb pdb:5TGA|rcsb pdb:6HHQ|rcsb pdb:5DC3|rcsb pdb:5I4L|rcsb pdb:6N8M|rcsb pdb:6N8N|rcsb pdb:6N8O|rcsb pdb:6I7O|rcsb pdb:7AZY|rcsb pdb:7B7D|rcsb pdb:7NRC|rcsb pdb:7NRD|reactome:R-SCE-1169408|reactome:R-SCE-5656169|rcsb pdb:5GAK|rcsb pdb:6Q8Y|ensemblfungi:YIL148W(gene)|ensemblfungi:YIL148W_mRNA(transcript)|ensemblfungi:YKR094C(gene)|ensemblfungi:YKR094C_mRNA(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0031386"(protein tag)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042254"(ribosome biogenesis)|rcsb pdb:6HD7|rcsb pdb:5ON6|rcsb pdb:5DAT|rcsb pdb:5JUO|rcsb pdb:5JUP|rcsb pdb:5JUS|rcsb pdb:5JUT|rcsb pdb:5JUU|rcsb pdb:5T62|rcsb pdb:5T6R|interpro:IPR038587|rcsb pdb:5MEI|rcsb pdb:5TBW|rcsb pdb:6GQ1|rcsb pdb:6GQB|rcsb pdb:6GQV|rcsb pdb:6R86|rcsb pdb:6S47|rcsb pdb:6NYO|rcsb pdb:6T4Q|rcsb pdb:6T7I|rcsb pdb:6T7T|rcsb pdb:6T83|rcsb pdb:6SNT|rcsb pdb:6SV4|rcsb pdb:6XIQ|rcsb pdb:6Z6J|rcsb pdb:6Z6K|sgd:YKR094C(identity)	ensembl:ENSG00000154710(gene)|ensembl:ENST00000439720(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|interpro:IPR002653(Zinc finger, A20-type)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR037191|interpro:IPR041545|entrezgene/locuslink:27342(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/03/16	rogid:6+5uVAktIpS9HyPHQ6BzXEuT/y0559292	rogid:JDHW8cuCB2z39j6a+LlkARnLfYo9606	intact-crc:ABE212A230E79CFB|rigid:Wx9NGINsPfl18eLv0ZOa7FGIPRA	false	-	sufficient binding region:14-504	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8N6L0	uniprotkb:P11972	intact:EBI-749265|uniprotkb:Q96MC3|ensembl:ENSP00000404220	intact:EBI-18232|uniprotkb:Q06207|uniprotkb:D6VZ86|ensemblfungi:YLR452C	psi-mi:kash5_human(display_long)|uniprotkb:KASH5(gene name)|psi-mi:KASH5(display_short)|uniprotkb:CCDC155(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 155(gene name synonym)|uniprotkb:KASH domain-containing protein 5(gene name synonym)	psi-mi:sst2_yeast(display_long)|uniprotkb:SST2(gene name)|psi-mi:SST2(display_short)|uniprotkb:L9324.9(orf name)|uniprotkb:YLR452C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11538659|imex:IM-24995-1712	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_653289.3|ensembl:ENSG00000161609(gene)|ensembl:ENST00000447857(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034397"(telomere localization)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051225"(spindle assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0090172"(microtubule cytoskeleton organization involved in homologous chromosome segregation)|go:"GO:0090220"(chromosome localization to nuclear envelope involved in homologous chromosome segregation)|go:"GO:0090619"(meiotic spindle pole)|interpro:IPR011992(EF-Hand type)|interpro:IPR028168|interpro:IPR028170|interpro:IPR039508|mint:Q8N6L0|rcsb pdb:6R2I|rcsb pdb:6WMF|entrezgene/locuslink:147872(identity)	refseq:NP_013557.1|sgd:S000004444|ensemblfungi:YLR452C(gene)|ensemblfungi:YLR452C_mRNA(transcript)|go:"GO:0000754"(adaptation of signaling pathway by response to pheromone involved in conjugation with cellular fusion)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0009968"(negative regulation of signal transduction)|go:"GO:0035556"(intracellular signal transduction)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR036305|interpro:IPR036388|interpro:IPR036390|interpro:IPR016137(Regulator of G protein signalling superfamily)|dip:DIP-2354N|mint:P11972|sgd:YLR452C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Wl9L7AcvDHCZuKjYLn8QgGIbZTc9606	rogid:a452jzptv3MtejNfc+LDrwSFSks559292	intact-crc:BB23A7BF9D418D26|rigid:rEa7jcAmNBUUvSpnXWFPLwT8+Fg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q53EZ4	uniprotkb:P11972	intact:EBI-747776|uniprotkb:Q32WF5|uniprotkb:Q3MV20|uniprotkb:Q5VY28|uniprotkb:Q6N034|ensembl:ENSP00000360540|uniprotkb:Q96H32|uniprotkb:Q9NVS7|uniprotkb:B2RDG8|intact:EBI-10173536|uniprotkb:D3DR37|intact:EBI-28973801	intact:EBI-18232|uniprotkb:Q06207|uniprotkb:D6VZ86|ensemblfungi:YLR452C	psi-mi:cep55_human(display_long)|uniprotkb:Up-regulated in colon cancer 6(gene name synonym)|uniprotkb:CEP55(gene name)|psi-mi:CEP55(display_short)|uniprotkb:URCC6(gene name synonym)|uniprotkb:C10orf3(gene name synonym)	psi-mi:sst2_yeast(display_long)|uniprotkb:SST2(gene name)|psi-mi:SST2(display_short)|uniprotkb:L9324.9(orf name)|uniprotkb:YLR452C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11538650|imex:IM-24995-1711	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001120654.1|refseq:NP_060601.3|ensembl:ENSG00000138180(gene)|ensembl:ENST00000371485(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0014066"(regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0030496"(midbody)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042802"(identical protein binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0061952"(midbody abscission)|go:"GO:0090543"(Flemming body)|go:"GO:1904888"(cranial skeletal system development)|interpro:IPR022008|interpro:IPR038926|mint:Q53EZ4|rcsb pdb:3E1R|rcsb pdb:3WUT|rcsb pdb:3WUU|rcsb pdb:3WUV|go:"GO:0005814"(centriole)|ensembl:ENSP00000360540|dip:DIP-44581N|entrezgene/locuslink:55165(identity)	refseq:NP_013557.1|sgd:S000004444|ensemblfungi:YLR452C(gene)|ensemblfungi:YLR452C_mRNA(transcript)|go:"GO:0000754"(adaptation of signaling pathway by response to pheromone involved in conjugation with cellular fusion)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0009968"(negative regulation of signal transduction)|go:"GO:0035556"(intracellular signal transduction)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR036305|interpro:IPR036388|interpro:IPR036390|interpro:IPR016137(Regulator of G protein signalling superfamily)|dip:DIP-2354N|mint:P11972|sgd:YLR452C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:tuo36vVb8ZgPDR81YjZFNEg559w9606	rogid:a452jzptv3MtejNfc+LDrwSFSks559292	intact-crc:71EA4DD6282FC69D|rigid:2CY9YiVxtRxh2T3VgAvA03Km7O0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P11747	intact:EBI-11523186	intact:EBI-18897|uniprotkb:D6W0I7|ensemblfungi:YML098W	-	psi-mi:taf13_yeast(display_long)|uniprotkb:TAF13(gene name)|psi-mi:TAF13(display_short)|uniprotkb:FUN81(gene name synonym)|uniprotkb:TAF19(gene name synonym)|uniprotkb:YML098W(locus name)|uniprotkb:TBP-associated factor 13(gene name synonym)|uniprotkb:TBP-associated factor 19 kDa(gene name synonym)|uniprotkb:TAFII-19(gene name synonym)|uniprotkb:Function unknown 81 protein(gene name synonym)	psi-mi:q5t063_human(display_short)|psi-mi:EBI-11523186(display_long)|uniprotkb:COQ3(gene name)|psi-mi:COQ3(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11538639|imex:IM-24995-1710	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013611.1|sgd:S000004564|ensemblfungi:YML098W(gene)|ensemblfungi:YML098W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|interpro:IPR003195(Transcription initiation factor IID, 18 kDa subunit)|interpro:IPR009072(Histone-fold)|reactome:R-SCE-674695|reactome:R-SCE-6807505|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-76042|dip:DIP-2054N|mint:P11747|sgd:YML098W(identity)	uniprotkb:Q5T063(uniprot-removed-ac)|entrezgene/locuslink:51805(identity)	-	-	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:N+MUCqLYlBQa1L2NcpyY5ImMIYM559292	rogid:A5Vp86bBACqUThgdTwfnKnqyE6c9606	intact-crc:D278F65A1C87A17C|rigid:8gx9Dw6LjBH5VRxbQobSaSpEuIc	false	-	sufficient binding region:61-310	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P10823	uniprotkb:Q9GZZ9	intact:EBI-7382|uniprotkb:D3DLR9|ensemblfungi:YER020W	intact:EBI-747805|uniprotkb:A6NJL3|uniprotkb:Q96ST1|uniprotkb:D3DNC8|ensembl:ENSP00000348565	psi-mi:gpa2_yeast(display_long)|uniprotkb:YER020W(locus name)|uniprotkb:GPA2(gene name)|psi-mi:GPA2(display_short)|uniprotkb:SSP101(gene name synonym)|uniprotkb:GP2-alpha(gene name synonym)	psi-mi:uba5_human(display_long)|uniprotkb:Ubiquitin-activating enzyme E1 domain-containing protein 1(gene name synonym)|uniprotkb:UFM1-activating enzyme(gene name synonym)|uniprotkb:ThiFP1(gene name synonym)|uniprotkb:UBA5(gene name)|psi-mi:UBA5(display_short)|uniprotkb:UBE1DC1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11538630|imex:IM-24995-1709	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000000822|refseq:NP_010937.3|mint:P10823|dip:DIP-4346N|ensemblfungi:YER020W(gene)|ensemblfungi:YER020W_mRNA(transcript)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0007165"(signal transduction)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0008361"(regulation of cell size)|go:"GO:0009757"(hexose mediated signaling)|go:"GO:0010255"(glucose mediated signaling pathway)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0030437"(ascospore formation)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR002975(Fungal G-protein, alpha subunit)|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|reactome:R-SCE-112043|reactome:R-SCE-202040|reactome:R-SCE-399997|reactome:R-SCE-416476|reactome:R-SCE-416482|reactome:R-SCE-418592|reactome:R-SCE-434316|reactome:R-SCE-9013148|sgd:YER020W(identity)	refseq:NP_079094.1|refseq:NP_938143.1|refseq:NP_001307139.1|refseq:NP_001308167.1|refseq:NP_001308168.1|ensembl:ENSG00000081307(gene)|ensembl:ENST00000356232(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030219"(megakaryocyte differentiation)|go:"GO:0032446"(protein modification by small protein conjugation)|go:"GO:0033146"(regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050905"(neuromuscular process)|go:"GO:0061709"(reticulophagy)|go:"GO:0071566"(UFM1 activating enzyme activity)|go:"GO:0071569"(protein ufmylation)|go:"GO:1990592"(protein K69-linked ufmylation)|interpro:IPR000594(UBA/THIF-type NAD/FAD binding fold)|interpro:IPR029752|interpro:IPR035985|rcsb pdb:3GUC|rcsb pdb:3H8V|rcsb pdb:5HKH|rcsb pdb:5IA8|rcsb pdb:5IAA|rcsb pdb:5L95|rcsb pdb:6H77|rcsb pdb:6H78|rcsb pdb:6H8C|reactome:R-HSA-983168|entrezgene/locuslink:79876(identity)	-	crc64:881B91792AE91748	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:ujQYVD/yCqR8/T2eRPygiuTD7Jg559292	rogid:qEziScb8+GA1rGAqnWD5O1w7MIg9606	intact-crc:C11079E6DAE0D07B|rigid:1hPwqqR0NCPfLZp0/Inpe8QzEmk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q02818	uniprotkb:P10823	intact:EBI-2622179|uniprotkb:Q7Z4J7|uniprotkb:B2RD64|uniprotkb:Q9BUR1|uniprotkb:Q15838|intact:EBI-28978015|ensembl:ENSP00000385211|ensembl:ENSP00000385923	intact:EBI-7382|uniprotkb:D3DLR9|ensemblfungi:YER020W	psi-mi:nucb1_human(display_long)|uniprotkb:NUC(gene name synonym)|uniprotkb:CALNUC(gene name synonym)|uniprotkb:NUCB1(gene name)|psi-mi:NUCB1(display_short)	psi-mi:gpa2_yeast(display_long)|uniprotkb:YER020W(locus name)|uniprotkb:GPA2(gene name)|psi-mi:GPA2(display_short)|uniprotkb:SSP101(gene name synonym)|uniprotkb:GP2-alpha(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11538619|imex:IM-24995-1708	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000385923|ensembl:ENSP00000385211|refseq:NP_006175.2|refseq:XP_016882334.1|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072718"(response to cisplatin)|go:"GO:0090498"(extrinsic component of Golgi membrane)|go:"GO:0098547"(lumenal side of Golgi membrane)|go:"GO:1903533"(regulation of protein targeting)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR040250|interpro:IPR040253|mint:Q02818|rcsb pdb:1SNL|reactome:R-HSA-381426|reactome:R-HSA-8957275|ensembl:ENSG00000104805(gene)|ensembl:ENST00000405315(transcript)|ensembl:ENST00000407032(transcript)|go:"GO:0001965"(G-protein alpha-subunit binding)|go:"GO:0003677"(DNA binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005769"(early endosome)|entrezgene/locuslink:4924(identity)	sgd:S000000822|refseq:NP_010937.3|mint:P10823|dip:DIP-4346N|ensemblfungi:YER020W(gene)|ensemblfungi:YER020W_mRNA(transcript)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0007165"(signal transduction)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0008361"(regulation of cell size)|go:"GO:0009757"(hexose mediated signaling)|go:"GO:0010255"(glucose mediated signaling pathway)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0030437"(ascospore formation)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR002975(Fungal G-protein, alpha subunit)|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|reactome:R-SCE-112043|reactome:R-SCE-202040|reactome:R-SCE-399997|reactome:R-SCE-416476|reactome:R-SCE-416482|reactome:R-SCE-418592|reactome:R-SCE-434316|reactome:R-SCE-9013148|sgd:YER020W(identity)	-	-	crc64:881B91792AE91748	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:exoVYPq5+NxEpgkm/gAQay/Uwuk9606	rogid:ujQYVD/yCqR8/T2eRPygiuTD7Jg559292	intact-crc:5C86870125CD1C74|rigid:KhM6hQ81nDdyd4SpwilDV4QHX/A	false	sufficient binding region:286-461	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q15025	uniprotkb:P12945	intact:EBI-357849|uniprotkb:A4F1W8|uniprotkb:O76008|uniprotkb:Q96EL9|uniprotkb:Q99833|uniprotkb:Q9H1J3|uniprotkb:B7Z699|uniprotkb:Q6N077|ensembl:ENSP00000317891|ensembl:ENSP00000428187|ensembl:ENSP00000430760|uniprotkb:A4F1W9|uniprotkb:A4F1X2|uniprotkb:A4F1X4|uniprotkb:A4F1X5|uniprotkb:A4F1X6|uniprotkb:A4F1X7|uniprotkb:A4F1X9|uniprotkb:E7EPY1|uniprotkb:E7ET96|uniprotkb:Q05KP3|uniprotkb:Q05KP4	intact:EBI-11868|ensemblfungi:YDL040C|uniprotkb:D6VRV5	psi-mi:tnip1_human(display_long)|uniprotkb:TNIP1(gene name)|psi-mi:TNIP1(display_short)|uniprotkb:KIAA0113(gene name synonym)|uniprotkb:NAF1(gene name synonym)|uniprotkb:Nef-associated factor 1(gene name synonym)|uniprotkb:HIV-1 Nef-interacting protein(gene name synonym)|uniprotkb:Virion-associated nuclear shuttling protein(gene name synonym)|uniprotkb:Nip40-1(gene name synonym)|uniprotkb:A20-binding inhibitor of NF-kappa-B activation 1(gene name synonym)	psi-mi:nat1_yeast(display_long)|uniprotkb:NAT1(gene name)|psi-mi:NAT1(display_short)|uniprotkb:AAA1(gene name synonym)|uniprotkb:YDL040C(locus name)|uniprotkb:D2720(orf name)|uniprotkb:Amino-terminal, alpha-amino, acetyltransferase 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11538722|imex:IM-24995-1719	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006049.3|refseq:NP_001239319.1|refseq:NP_001239320.1|refseq:NP_001239321.1|refseq:NP_001239322.1|refseq:NP_001245383.1|dip:DIP-27577N|refseq:NP_001239315.1|ensembl:ENSG00000145901(gene)|ensembl:ENST00000315050(transcript)|ensembl:ENST00000521591(transcript)|ensembl:ENST00000522226(transcript)|go:"GO:0002755"(MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0006952"(defense response)|go:"GO:0006954"(inflammatory response)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0009101"(glycoprotein biosynthetic process)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0085032"(modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade)|go:"GO:1903003"(positive regulation of protein deubiquitination)|interpro:IPR033372|mint:Q15025|reactome:R-HSA-5689896|go:"GO:0051019"(mitogen-activated protein kinase binding)|refseq:NP_001239314.1|refseq:NP_001245384.1|refseq:NP_001245385.1|refseq:XP_006714814.1|refseq:XP_006714815.1|entrezgene/locuslink:10318(identity)	ensemblfungi:YDL040C(gene)|ensemblfungi:YDL040C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006474"(N-terminal protein amino acid acetylation)|go:"GO:0017196"(N-terminal peptidyl-methionine acetylation)|go:"GO:0031415"(NatA complex)|go:"GO:0043022"(ribosome binding)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR021183|rcsb pdb:4HNW|rcsb pdb:4HNY|rcsb pdb:4XNH|rcsb pdb:4XPD|rcsb pdb:4Y49|rcsb pdb:6HD5|rcsb pdb:6HD7|rcsb pdb:6O07|refseq:NP_010244.1|sgd:S000002198|dip:DIP-6329N|mint:P12945|sgd:YDL040C(identity)	-	-	crc64:DCFB870D049F91E6	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:16Vjb5CuGTAbW2M22qbCxgXtV1o9606	rogid:uzbL/wNoQ9nAcZzglVrbI4GKzOg559292	intact-crc:3C9AD7CF5B9C4546|rigid:nJkoXSkwLxk4qiNvOrjpzpV7Uos	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P12709	uniprotkb:Q13501	intact:EBI-7238|uniprotkb:D6VQJ0|ensemblfungi:YBR196C	intact:EBI-307104|uniprotkb:Q13446|uniprotkb:Q9BUV7|uniprotkb:Q9BVS6|uniprotkb:Q9UEU1|uniprotkb:A6NFN7|uniprotkb:B2R661|uniprotkb:B3KUW5|intact:EBI-28976133|ensembl:ENSP00000374455	psi-mi:g6pi_yeast(display_long)|uniprotkb:PGI1(gene name)|psi-mi:PGI1(display_short)|uniprotkb:YBR196C(locus name)|uniprotkb:YBR1406(orf name)|uniprotkb:Phosphoglucose isomerase(gene name synonym)|uniprotkb:Phosphohexose isomerase(gene name synonym)	psi-mi:sqstm_human(display_long)|uniprotkb:SQSTM1(gene name)|psi-mi:SQSTM1(display_short)|uniprotkb:ORCA(gene name synonym)|uniprotkb:OSIL(gene name synonym)|uniprotkb:Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa(gene name synonym)|uniprotkb:Ubiquitin-binding protein p62(gene name synonym)|uniprotkb:EBI3-associated protein of 60 kDa(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11538713|imex:IM-24995-1718	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009755.1|sgd:S000000400|mint:P12709|dip:DIP-1605N|ensemblfungi:YBR196C(gene)|ensemblfungi:YBR196C_mRNA(transcript)|go:"GO:0004347"(glucose-6-phosphate isomerase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006096"(glycolytic process)|go:"GO:0048029"(monosaccharide binding)|go:"GO:0051156"(glucose 6-phosphate metabolic process)|interpro:IPR001672("Phosphoglucose isomerase (PGI)")|interpro:IPR018189|interpro:IPR023096|interpro:IPR035476|interpro:IPR035482|reactome:R-SCE-5628897|reactome:R-SCE-6798695|reactome:R-SCE-70171|reactome:R-SCE-70263|sgd:YBR196C(identity)	ensembl:ENST00000360718|ensembl:ENSP00000353944|ensembl:ENSP00000374455|ensembl:ENSG00000161011(gene)|ensembl:ENST00000389805(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0000423"(mitophagy)|go:"GO:0000932"(P-body)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002376"(immune system process)|go:"GO:0002931"(response to ischemia)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006914"(autophagy)|go:"GO:0006915"(apoptotic process)|go:"GO:0007032"(endosome organization)|go:"GO:0008104"(protein localization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016197"(endosomal transport)|go:"GO:0016234"(inclusion body)|go:"GO:0016235"(aggresome)|go:"GO:0016236"(macroautophagy)|go:"GO:0016605"(PML body)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030017"(sarcomere)|go:"GO:0030154"(cell differentiation)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035973"(aggrephagy)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046578"(regulation of Ras protein signal transduction)|go:"GO:0061635"(regulation of protein complex stability)|go:"GO:0061912"(selective autophagy)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:0097225"(sperm midpiece)|go:"GO:0097413"(Lewy body)|go:"GO:0098780"(response to mitochondrial depolarisation)|go:"GO:1900273"(positive regulation of long-term synaptic potentiation)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1905719"(protein localization to perinuclear region of cytoplasm)|interpro:IPR000270(Octicosapeptide/Phox/Bem1p)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR009060(UBA-like)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR033741|go:"GO:0044753"(amphisome)|interpro:IPR034866|interpro:IPR043145|mint:Q13501|rcsb pdb:1Q02|rcsb pdb:2JY7|rcsb pdb:2JY8|rcsb pdb:2K0B|rcsb pdb:2KNV|go:"GO:0044754"(autolysosome)|rcsb pdb:4MJS|rcsb pdb:4UF8|rcsb pdb:4UF9|go:"GO:0044877"(protein-containing complex binding)|rcsb pdb:5YP7|rcsb pdb:5YP8|rcsb pdb:5YPA|rcsb pdb:5YPB|rcsb pdb:5YPC|rcsb pdb:5YPE|rcsb pdb:5YPF|rcsb pdb:5YPG|rcsb pdb:5YPH|rcsb pdb:6JM4|rcsb pdb:6KHZ|rcsb pdb:6MJ7|rcsb pdb:6TGY|rcsb pdb:6TH3|reactome:R-HSA-205043|reactome:R-HSA-209543|reactome:R-HSA-209560|reactome:R-HSA-5205685|reactome:R-HSA-9020702|reactome:R-HSA-9664873|refseq:NP_001135770.1|refseq:NP_001135771.1|refseq:NP_003891.1|dip:DIP-34443N|refseq:XP_016865499.1|entrezgene/locuslink:8878(identity)	-	crc64:556D3D3B77EED052	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:hle82HMm3aAvYrUuuGoaxqyg/VA559292	rogid:paIcBLmyiv1+D9QMym5MY3yc8MI9606	intact-crc:E9910060C1860C0F|rigid:qlvg6UNiNpdoIDTLjzlG09foy/w	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9C0F1	uniprotkb:P12612	intact:EBI-744115|uniprotkb:A8K8W9|uniprotkb:B3KT53|uniprotkb:Q8IXZ4|uniprotkb:A8MW11|uniprotkb:D3DP42|ensembl:ENSP00000296519|ensembl:ENSP00000380009|ensembl:ENSP00000423153	intact:EBI-19045|uniprotkb:D6VSJ6|ensemblfungi:YDR212W	psi-mi:cep44_human(display_long)|uniprotkb:HBV PreS1-transactivated protein 3(gene name synonym)|uniprotkb:CEP44(gene name)|psi-mi:CEP44(display_short)|uniprotkb:KIAA1712(gene name synonym)	psi-mi:tcpa_yeast(display_long)|uniprotkb:TCP1(gene name)|psi-mi:TCP1(display_short)|uniprotkb:CCT1(gene name synonym)|uniprotkb:YDR212W(locus name)|uniprotkb:YD8142.13(orf name)|uniprotkb:YD8142B.04(orf name)|uniprotkb:CCT-alpha(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11538704|imex:IM-24995-1717	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001035247.1|refseq:NP_001138786.1|refseq:XP_011530587.1|refseq:XP_011530588.1|refseq:XP_011530589.1|refseq:XP_016864143.1|refseq:XP_016864144.1|ensembl:ENSG00000164118(gene)|ensembl:ENST00000296519(transcript)|ensembl:ENST00000396791(transcript)|ensembl:ENST00000503780(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007099"(centriole replication)|go:"GO:0008017"(microtubule binding)|go:"GO:0010457"(centriole-centriole cohesion)|go:"GO:0030496"(midbody)|interpro:IPR029157|interpro:IPR033603|mint:Q9C0F1|entrezgene/locuslink:80817(identity)	refseq:NP_010498.1|sgd:S000002620|ensemblfungi:YDR212W(gene)|ensemblfungi:YDR212W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012715(T-complex protein 1, alpha subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|rcsb pdb:4V81|rcsb pdb:4V8R|rcsb pdb:4V94|rcsb pdb:5GW4|rcsb pdb:5GW5|rcsb pdb:6KRD|rcsb pdb:6KRE|rcsb pdb:6KS6|rcsb pdb:6KS7|rcsb pdb:6KS8|reactome:R-SCE-390471|reactome:R-SCE-6814122|dip:DIP-2965N|mint:P12612|sgd:YDR212W(identity)	-	-	crc64:02C625D329359E61	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:gDTC64oDhudGdsssC7v+suIHZkA9606	rogid:xWMsvY106Y6yQ54SOif2UlScafM559292	intact-crc:19E9B36016AFC5C0|rigid:/6ENGopr6rtDq1OlgLpBBq/+eik	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96BR9	uniprotkb:P12612	intact:EBI-742740|uniprotkb:Q8IUL5|uniprotkb:Q8IWR9|uniprotkb:Q8N2Y5|uniprotkb:Q96BX0|ensembl:ENSP00000362609	intact:EBI-19045|uniprotkb:D6VSJ6|ensemblfungi:YDR212W	psi-mi:zbt8a_human(display_long)|uniprotkb:ZBTB8A(gene name)|psi-mi:ZBTB8A(display_short)|uniprotkb:BOZF1(gene name synonym)|uniprotkb:BTB/POZ and zinc-finger domain-containing factor(gene name synonym)|uniprotkb:BTB/POZ and zinc-finger domains factor on chromosome 1(gene name synonym)	psi-mi:tcpa_yeast(display_long)|uniprotkb:TCP1(gene name)|psi-mi:TCP1(display_short)|uniprotkb:CCT1(gene name synonym)|uniprotkb:YDR212W(locus name)|uniprotkb:YD8142.13(orf name)|uniprotkb:YD8142B.04(orf name)|uniprotkb:CCT-alpha(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11538695|imex:IM-24995-1716	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000160062(gene)|ensembl:ENST00000373510(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|refseq:NP_001035531.2|refseq:NP_001278425.1|entrezgene/locuslink:653121(identity)	refseq:NP_010498.1|sgd:S000002620|ensemblfungi:YDR212W(gene)|ensemblfungi:YDR212W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012715(T-complex protein 1, alpha subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|rcsb pdb:4V81|rcsb pdb:4V8R|rcsb pdb:4V94|rcsb pdb:5GW4|rcsb pdb:5GW5|rcsb pdb:6KRD|rcsb pdb:6KRE|rcsb pdb:6KS6|rcsb pdb:6KS7|rcsb pdb:6KS8|reactome:R-SCE-390471|reactome:R-SCE-6814122|dip:DIP-2965N|mint:P12612|sgd:YDR212W(identity)	-	-	crc64:02C625D329359E61	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:tsrPT2tHvuBryODKgRXnceXz9s09606	rogid:xWMsvY106Y6yQ54SOif2UlScafM559292	intact-crc:BB145E81AED0CCEB|rigid:eOKcrORbn1aYRa7IKh+kR33ysqI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P12612	uniprotkb:Q15041	intact:EBI-19045|uniprotkb:D6VSJ6|ensemblfungi:YDR212W	intact:EBI-714543|ensembl:ENSP00000306788|uniprotkb:B7Z6S5|uniprotkb:B7Z791|uniprotkb:F5GXP4	psi-mi:tcpa_yeast(display_long)|uniprotkb:TCP1(gene name)|psi-mi:TCP1(display_short)|uniprotkb:CCT1(gene name synonym)|uniprotkb:YDR212W(locus name)|uniprotkb:YD8142.13(orf name)|uniprotkb:YD8142B.04(orf name)|uniprotkb:CCT-alpha(gene name synonym)	psi-mi:ar6p1_human(display_long)|uniprotkb:ARL6IP(gene name synonym)|uniprotkb:ARL6IP1(gene name)|psi-mi:ARL6IP1(display_short)|uniprotkb:KIAA0069(gene name synonym)|uniprotkb:ARMER(gene name synonym)|uniprotkb:Apoptotic regulator in the membrane of the endoplasmic reticulum(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11538686|imex:IM-24995-1715	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010498.1|sgd:S000002620|ensemblfungi:YDR212W(gene)|ensemblfungi:YDR212W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012715(T-complex protein 1, alpha subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|rcsb pdb:4V81|rcsb pdb:4V8R|rcsb pdb:4V94|rcsb pdb:5GW4|rcsb pdb:5GW5|rcsb pdb:6KRD|rcsb pdb:6KRE|rcsb pdb:6KS6|rcsb pdb:6KS7|rcsb pdb:6KS8|reactome:R-SCE-390471|reactome:R-SCE-6814122|dip:DIP-2965N|mint:P12612|sgd:YDR212W(identity)	refseq:NP_055976.1|ensembl:ENSG00000170540(gene)|ensembl:ENST00000304414(transcript)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006613"(cotranslational protein targeting to membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0071787"(endoplasmic reticulum tubular network formation)|go:"GO:1903371"(regulation of endoplasmic reticulum tubular network organization)|go:"GO:1990809"(endoplasmic reticulum tubular network membrane organization)|interpro:IPR033301|mint:Q15041|go:"GO:0002038"(positive regulation of L-glutamate import across plasma membrane)|refseq:NP_001300787.1|entrezgene/locuslink:23204(identity)	-	crc64:02C625D329359E61	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:xWMsvY106Y6yQ54SOif2UlScafM559292	rogid:3fjkoyvUx25po7xsPcXgpjEeLJg9606	intact-crc:85A034A807FB5D04|rigid:hg9kriFmHA5VRfK4C/zEWeN7Jeg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P12612	uniprotkb:P23497-2	intact:EBI-19045|uniprotkb:D6VSJ6|ensemblfungi:YDR212W	intact:EBI-6589365|ensembl:ENSP00000386404	psi-mi:tcpa_yeast(display_long)|uniprotkb:TCP1(gene name)|psi-mi:TCP1(display_short)|uniprotkb:CCT1(gene name synonym)|uniprotkb:YDR212W(locus name)|uniprotkb:YD8142.13(orf name)|uniprotkb:YD8142B.04(orf name)|uniprotkb:CCT-alpha(gene name synonym)	psi-mi:p23497-2(display_long)|uniprotkb:SP100(isoform synonym)|uniprotkb:SP100(gene name)|psi-mi:SP100(display_short)|uniprotkb:Nuclear dot-associated Sp100 protein(gene name synonym)|uniprotkb:Speckled 100 kDa(gene name synonym)|uniprotkb:SP100A(isoform synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11538677|imex:IM-24995-1714	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010498.1|sgd:S000002620|ensemblfungi:YDR212W(gene)|ensemblfungi:YDR212W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012715(T-complex protein 1, alpha subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|rcsb pdb:4V81|rcsb pdb:4V8R|rcsb pdb:4V94|rcsb pdb:5GW4|rcsb pdb:5GW5|rcsb pdb:6KRD|rcsb pdb:6KRE|rcsb pdb:6KS6|rcsb pdb:6KS7|rcsb pdb:6KS8|reactome:R-SCE-390471|reactome:R-SCE-6814122|dip:DIP-2965N|mint:P12612|sgd:YDR212W(identity)	intact:EBI-751145(isoform-parent)|uniprotkb:P23497-2(isoform-parent)|ensembl:ENSG00000067066(gene)|ensembl:ENST00000409341(transcript)|entrezgene/locuslink:6672(identity)	-	crc64:02C625D329359E61	isoform-comment:Major isoform.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:xWMsvY106Y6yQ54SOif2UlScafM559292	rogid:HrcogLANB///4vkSYtZ7OtzOb2k9606	intact-crc:41CFCC5B4517281C|rigid:b276Sfs8Vc0EZEcpKKwu77YIemc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P12612	uniprotkb:O60232	intact:EBI-19045|uniprotkb:D6VSJ6|ensemblfungi:YDR212W	intact:EBI-741415|ensembl:ENSP00000312318	psi-mi:tcpa_yeast(display_long)|uniprotkb:TCP1(gene name)|psi-mi:TCP1(display_short)|uniprotkb:CCT1(gene name synonym)|uniprotkb:YDR212W(locus name)|uniprotkb:YD8142.13(orf name)|uniprotkb:YD8142B.04(orf name)|uniprotkb:CCT-alpha(gene name synonym)	psi-mi:znrd2_human(display_long)|uniprotkb:ZNRD2(gene name)|psi-mi:ZNRD2(display_short)|uniprotkb:Autoantigen p27(gene name synonym)|uniprotkb:SSSCA1(gene name synonym)|uniprotkb:Sjoegren syndrome/scleroderma autoantigen 1(gene name synonym)|uniprotkb:Zinc ribbon domain-containing protein 2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11538668|imex:IM-24995-1713	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010498.1|sgd:S000002620|ensemblfungi:YDR212W(gene)|ensemblfungi:YDR212W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012715(T-complex protein 1, alpha subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|rcsb pdb:4V81|rcsb pdb:4V8R|rcsb pdb:4V94|rcsb pdb:5GW4|rcsb pdb:5GW5|rcsb pdb:6KRD|rcsb pdb:6KRE|rcsb pdb:6KS6|rcsb pdb:6KS7|rcsb pdb:6KS8|reactome:R-SCE-390471|reactome:R-SCE-6814122|dip:DIP-2965N|mint:P12612|sgd:YDR212W(identity)	refseq:NP_006387.1|ensembl:ENSG00000173465(gene)|ensembl:ENST00000309328(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0051301"(cell division)|interpro:IPR009563(Sjogrens syndrome scleroderma autoantigen 1)|rcsb pdb:6HCZ|entrezgene/locuslink:10534(identity)	-	crc64:02C625D329359E61	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:xWMsvY106Y6yQ54SOif2UlScafM559292	rogid:Uou80pZneoL39/0YYzb1TAbiB2I9606	intact-crc:8AEBC8217AF42E78|rigid://TjGLfHSuH0wACVj1nKRpTLARQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P14905	uniprotkb:O95273	intact:EBI-4163|uniprotkb:D6VSI0|ensemblfungi:YDR197W	intact:EBI-748961|uniprotkb:A8K3Q0|uniprotkb:A8K3U2|uniprotkb:Q6ZQN9|uniprotkb:Q7Z519|uniprotkb:Q8NBS7|uniprotkb:Q8NBY2|uniprotkb:Q9NS19|uniprotkb:Q9NYH3|uniprotkb:Q9UHX9|ensembl:ENSP00000300213	psi-mi:cbs2_yeast(display_long)|uniprotkb:CBS2(gene name)|psi-mi:CBS2(display_short)|uniprotkb:CBP7(gene name synonym)|uniprotkb:YDR197W(locus name)|uniprotkb:YD9346.08(orf name)	psi-mi:ccdb1_human(display_long)|uniprotkb:Grap2 and cyclin-D-interacting protein(gene name synonym)|uniprotkb:Human homolog of Maid(gene name synonym)|uniprotkb:CCNDBP1(gene name)|psi-mi:CCNDBP1(display_short)|uniprotkb:DIP1(gene name synonym)|uniprotkb:GCIP(gene name synonym)|uniprotkb:HHM(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11538779|imex:IM-24995-1725	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010483.1|sgd:S000002605|interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|interpro:IPR013752(Ketopantoate reductase ApbA/PanE, C-terminal)|interpro:IPR013328(Dehydrogenase, multihelical)|ensemblfungi:YDR197W(gene)|ensemblfungi:YDR197W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005761"(mitochondrial ribosome)|go:"GO:0008677"(2-dehydropantoate 2-reductase activity)|go:"GO:0031314"(extrinsic component of mitochondrial inner membrane)|go:"GO:0045182"(translation regulator activity)|go:"GO:0050661"(NADP binding)|go:"GO:0070131"(positive regulation of mitochondrial translation)|sgd:YDR197W(identity)	refseq:NP_036274.3|ensembl:ENSG00000166946(gene)|ensembl:ENST00000300213(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0016604"(nuclear body)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR026907|mint:O95273|rcsb pdb:3AY5|entrezgene/locuslink:23582(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:KEEVJQEjHPVx7AU4JFmwGnoEptU559292	rogid:Vi9aoFc+Mov6P3X6KGmsTxXqxvM9606	intact-crc:D2EE1D0112287A8C|rigid:q/3T4XXuCPOQCtjMxHiqDceUpZU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q86V42-3	uniprotkb:P13186	intact:EBI-11523323|ensembl:ENSP00000481212	intact:EBI-9723|uniprotkb:Q12384|ensemblfungi:YLR096W|uniprotkb:D6VY96	psi-mi:q86v42-3(display_long)|uniprotkb:FAM124A(gene name)|psi-mi:FAM124A(display_short)	psi-mi:kin2_yeast(display_long)|uniprotkb:L8004.3(orf name)|uniprotkb:YLR096W(locus name)|uniprotkb:KIN2(gene name)|psi-mi:KIN2(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11538768|imex:IM-24995-1724	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000150510(gene)|ensembl:ENST00000615498(transcript)|intact:EBI-744506(isoform-parent)|entrezgene/locuslink:220108(identity)	go:"GO:0005935"(cellular bud neck)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006887"(exocytosis)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0045921"(positive regulation of exocytosis)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903896"(positive regulation of IRE1-mediated unfolded protein response)|interpro:IPR000719(Protein kinase, core)|ensemblfungi:YLR096W(gene)|ensemblfungi:YLR096W_mRNA(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005934"(cellular bud tip)|interpro:IPR001772(Kinase-associated KA1)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR028375|reactome:R-SCE-1632852|reactome:R-SCE-380972|refseq:NP_013197.1|sgd:S000004086|dip:DIP-6276N|mint:P13186|sgd:YLR096W(identity)	-	-	crc64:AC2660BF3CA69600	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:tWx14HsCfMtI8yIrYJCt8V4lr+c9606	rogid:OkRLTXiGL1oYkrvvB/KznlaEvrE559292	intact-crc:D4AF28267E6204E9|rigid:col8/KUv7mr3nLS9KHMq/YIXCnM	false	sufficient binding region:1-288	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9Y5P4-2	uniprotkb:P13130	intact:EBI-11156432|ensembl:ENSP00000493563|ensembl:ENSP00000495446|ensembl:ENSP00000496243	intact:EBI-11523294|uniprotkb:D3DL88|ensemblfungi:YHR139C	psi-mi:q9y5p4-2(display_long)|uniprotkb:Goodpasture antigen-binding protein(gene name synonym)|uniprotkb:STARD11(gene name synonym)|uniprotkb:START domain-containing protein 11(gene name synonym)|uniprotkb:StAR-related lipid transfer protein 11(gene name synonym)|uniprotkb:CERT(isoform synonym)|uniprotkb:Delta26(isoform synonym)|uniprotkb:GPBPD26(isoform synonym)|uniprotkb:CERT(gene name synonym)|uniprotkb:COL4A3BP(gene name synonym)|uniprotkb:CERT1(gene name)|psi-mi:CERT1(display_short)|uniprotkb:Collagen type IV alpha-3-binding protein(gene name synonym)	psi-mi:ss100_yeast(display_long)|uniprotkb:SPS100(gene name)|psi-mi:SPS100(display_short)|uniprotkb:YHR139C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11538759|imex:IM-24995-1723	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000113163(gene)|ensembl:ENST00000644445(transcript)|ensembl:ENST00000645483(transcript)|ensembl:ENST00000646511(transcript)|intact:EBI-739994(isoform-parent)|uniprotkb:Q9Y5P4-2(isoform-parent)|entrezgene/locuslink:10087(identity)	interpro:IPR006034(Asparaginase/glutaminase)|refseq:NP_012007.1|sgd:S000001181|ensemblfungi:YHR139C(gene)|ensemblfungi:YHR139C_mRNA(transcript)|go:"GO:0030476"(ascospore wall assembly)|interpro:IPR036152|sgd:YHR139C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/03/16	rogid:UXQeqtW4rknHeYKQlqBZ9HMX8Qs9606	rogid:ThKMilyLHPEAiJu+3ty4DXcUEE4559292	intact-crc:3C77B1055EE0492C|rigid:VsTEV5Bu7ezKNSFK0ZMGd3Tp0yo	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UMX0	uniprotkb:P13130	intact:EBI-741480|uniprotkb:Q8IXS9|uniprotkb:Q8N2Q3|uniprotkb:Q9H0T8|uniprotkb:Q9H3R4|uniprotkb:Q9HAZ5|intact:EBI-28967608|ensembl:ENSP00000365576|uniprotkb:Q5T6J5|uniprotkb:Q5T6J9|uniprotkb:A0A024R284	intact:EBI-11523294|uniprotkb:D3DL88|ensemblfungi:YHR139C	psi-mi:ubql1_human(display_long)|uniprotkb:Protein linking IAP with cytoskeleton 1(gene name synonym)|uniprotkb:UBQLN1(gene name)|psi-mi:UBQLN1(display_short)|uniprotkb:DA41(gene name synonym)|uniprotkb:PLIC1(gene name synonym)	psi-mi:ss100_yeast(display_long)|uniprotkb:SPS100(gene name)|psi-mi:SPS100(display_short)|uniprotkb:YHR139C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11538750|imex:IM-24995-1722	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000257468|ensembl:ENSP00000257468|ensembl:ENSP00000365576|ensembl:ENSG00000135018(gene)|ensembl:ENST00000376395(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000502"(proteasome complex)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016235"(aggresome)|go:"GO:0016236"(macroautophagy)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0019900"(kinase binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035973"(aggrephagy)|go:"GO:0042802"(identical protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0097352"(autophagosome maturation)|go:"GO:1901340"(negative regulation of store-operated calcium channel activity)|go:"GO:1902175"(regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)|interpro:IPR000626(Ubiquitin)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR028430|interpro:IPR029071|mint:Q9UMX0|rcsb pdb:2JY5|rcsb pdb:2JY6|rcsb pdb:2KLC|reactome:R-HSA-8856825|refseq:NP_038466.2|refseq:NP_444295.1|dip:DIP-41629N|entrezgene/locuslink:29979(identity)	interpro:IPR006034(Asparaginase/glutaminase)|refseq:NP_012007.1|sgd:S000001181|ensemblfungi:YHR139C(gene)|ensemblfungi:YHR139C_mRNA(transcript)|go:"GO:0030476"(ascospore wall assembly)|interpro:IPR036152|sgd:YHR139C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/03/16	rogid:nCFfZbGCTvRYaXhQ4R99XblslvM9606	rogid:ThKMilyLHPEAiJu+3ty4DXcUEE4559292	intact-crc:C97C14EFE6C8CD13|rigid:KGsi58uLomNB8/QsHP3n0SrQW/M	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P13130	uniprotkb:Q8TAP6	intact:EBI-11523294|uniprotkb:D3DL88|ensemblfungi:YHR139C	intact:EBI-742887|ensembl:ENSP00000262127|uniprotkb:Q658N5|uniprotkb:Q9H9U7|uniprotkb:B0YJB2|uniprotkb:B4DXG5|uniprotkb:B4DZW1	psi-mi:ss100_yeast(display_long)|uniprotkb:SPS100(gene name)|psi-mi:SPS100(display_short)|uniprotkb:YHR139C(locus name)	psi-mi:cep76_human(display_long)|uniprotkb:CEP76(gene name)|psi-mi:CEP76(display_short)|uniprotkb:C18orf9(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11538741|imex:IM-24995-1721	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR006034(Asparaginase/glutaminase)|refseq:NP_012007.1|sgd:S000001181|ensemblfungi:YHR139C(gene)|ensemblfungi:YHR139C_mRNA(transcript)|go:"GO:0030476"(ascospore wall assembly)|interpro:IPR036152|sgd:YHR139C(identity)	refseq:NP_079175.2|ensembl:ENSG00000101624(gene)|ensembl:ENST00000262127(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0046599"(regulation of centriole replication)|interpro:IPR028926|interpro:IPR038765|mint:Q8TAP6|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_001258918.1|entrezgene/locuslink:79959(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/03/16	rogid:ThKMilyLHPEAiJu+3ty4DXcUEE4559292	rogid:fWzb8oIU35oVWomyDrf8u5sbxUk9606	intact-crc:2989DB271DCC1AC2|rigid:YRjep4LcIYNbHrjtIgVJr+fIq6A	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P12945	uniprotkb:Q8N6L0	intact:EBI-11868|ensemblfungi:YDL040C|uniprotkb:D6VRV5	intact:EBI-749265|uniprotkb:Q96MC3|ensembl:ENSP00000404220	psi-mi:nat1_yeast(display_long)|uniprotkb:NAT1(gene name)|psi-mi:NAT1(display_short)|uniprotkb:AAA1(gene name synonym)|uniprotkb:YDL040C(locus name)|uniprotkb:D2720(orf name)|uniprotkb:Amino-terminal, alpha-amino, acetyltransferase 1(gene name synonym)	psi-mi:kash5_human(display_long)|uniprotkb:KASH5(gene name)|psi-mi:KASH5(display_short)|uniprotkb:CCDC155(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 155(gene name synonym)|uniprotkb:KASH domain-containing protein 5(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11538732|imex:IM-24995-1720	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YDL040C(gene)|ensemblfungi:YDL040C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006474"(N-terminal protein amino acid acetylation)|go:"GO:0017196"(N-terminal peptidyl-methionine acetylation)|go:"GO:0031415"(NatA complex)|go:"GO:0043022"(ribosome binding)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR021183|rcsb pdb:4HNW|rcsb pdb:4HNY|rcsb pdb:4XNH|rcsb pdb:4XPD|rcsb pdb:4Y49|rcsb pdb:6HD5|rcsb pdb:6HD7|rcsb pdb:6O07|refseq:NP_010244.1|sgd:S000002198|dip:DIP-6329N|mint:P12945|sgd:YDL040C(identity)	refseq:NP_653289.3|ensembl:ENSG00000161609(gene)|ensembl:ENST00000447857(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034397"(telomere localization)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051225"(spindle assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0090172"(microtubule cytoskeleton organization involved in homologous chromosome segregation)|go:"GO:0090220"(chromosome localization to nuclear envelope involved in homologous chromosome segregation)|go:"GO:0090619"(meiotic spindle pole)|interpro:IPR011992(EF-Hand type)|interpro:IPR028168|interpro:IPR028170|interpro:IPR039508|mint:Q8N6L0|rcsb pdb:6R2I|rcsb pdb:6WMF|entrezgene/locuslink:147872(identity)	-	crc64:DCFB870D049F91E6	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:uzbL/wNoQ9nAcZzglVrbI4GKzOg559292	rogid:Wl9L7AcvDHCZuKjYLn8QgGIbZTc9606	intact-crc:A3E677235ACE2D33|rigid:arqSMYQnLNdGXT0Ig8HGi8iPt2c	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9BSE2	uniprotkb:P15303	intact:EBI-8649725|ensembl:ENSP00000295694|ensembl:ENSP00000384748|intact:MINT-8163648|uniprotkb:D3DVB8|uniprotkb:B2RE22	intact:EBI-16584|ensemblfungi:YPR181C|uniprotkb:D6W4I1	psi-mi:tmm79_human(display_long)|uniprotkb:MATT(gene name synonym)|uniprotkb:TMEM79(gene name)|psi-mi:TMEM79(display_short)|uniprotkb:Mattrin(gene name synonym)	psi-mi:sec23_yeast(display_long)|uniprotkb:SEC23(gene name)|psi-mi:SEC23(display_short)|uniprotkb:P9705.14(orf name)|uniprotkb:YPR181C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11538835|imex:IM-24995-1731	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000163472(gene)|ensembl:ENST00000295694(transcript)|ensembl:ENST00000405535(transcript)|go:"GO:0002070"(epithelial cell maturation)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031069"(hair follicle morphogenesis)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0042335"(cuticle development)|go:"GO:0042802"(identical protein binding)|go:"GO:0045055"(regulated exocytosis)|go:"GO:0045684"(positive regulation of epidermis development)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070268"(cornification)|mint:Q9BSE2|refseq:NP_115699.1|entrezgene/locuslink:84283(identity)	refseq:NP_015507.1|sgd:S000006385|ensemblfungi:YPR181C(gene)|ensemblfungi:YPR181C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003400"(regulation of COPII vesicle coating)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016236"(macroautophagy)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0061709"(reticulophagy)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:0090110"(COPII-coated vesicle cargo loading)|interpro:IPR006895(Zinc finger, Sec23/Sec24-type)|interpro:IPR006896(Sec23/Sec24 trunk region)|interpro:IPR006900(Sec23/Sec24 helical region)|interpro:IPR007123(Gelsolin region)|interpro:IPR012990(Sec23/Sec24 beta-sandwich)|interpro:IPR029006|interpro:IPR036174|interpro:IPR036175|interpro:IPR036180|interpro:IPR036465|interpro:IPR037364|interpro:IPR037550|rcsb pdb:1M2O|rcsb pdb:2QTV|rcsb pdb:4BZI|rcsb pdb:6GNI|rcsb pdb:6ZGA|reactome:R-SCE-204005|reactome:R-SCE-5694530|reactome:R-SCE-983170|rcsb pdb:1M2V|dip:DIP-2232N|mint:P15303|sgd:YPR181C(identity)	-	comment:mint	crc64:69811913848265FB	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:QdmILKEdTJzJUhBdigw/4vC4R3o9606	rogid:IqC3qOrbef6aMHBztUW5+7DZ4IQ559292	intact-crc:2AD5FA6F12AACFEF|rigid:24mlGqSFa+DOaxDKtlfF/GK7GEg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8IYX7	uniprotkb:P15303	intact:EBI-3957636|ensembl:ENSP00000369907|intact:EBI-10174528|uniprotkb:A8K880|uniprotkb:Q5VY58	intact:EBI-16584|ensemblfungi:YPR181C|uniprotkb:D6W4I1	psi-mi:saxo1_human(display_long)|uniprotkb:SAXO1(gene name)|psi-mi:SAXO1(display_short)|uniprotkb:C9orf138(gene name synonym)|uniprotkb:FAM154A(gene name synonym)	psi-mi:sec23_yeast(display_long)|uniprotkb:SEC23(gene name)|psi-mi:SEC23(display_short)|uniprotkb:P9705.14(orf name)|uniprotkb:YPR181C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11538826|imex:IM-24995-1730	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000155875(gene)|ensembl:ENST00000380534(transcript)|go:"GO:0005814"(centriole)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0008017"(microtubule binding)|go:"GO:0009631"(cold acclimation)|go:"GO:0030030"(cell projection organization)|go:"GO:0031514"(motile cilium)|go:"GO:0034453"(microtubule anchoring)|go:"GO:0036064"(ciliary basal body)|go:"GO:0036126"(sperm flagellum)|go:"GO:0045724"(positive regulation of cilium assembly)|go:"GO:0050821"(protein stabilization)|go:"GO:0070417"(cellular response to cold)|interpro:IPR033336|refseq:NP_714918.2|refseq:NP_001273978.1|refseq:NP_001273979.1|entrezgene/locuslink:158297(identity)	refseq:NP_015507.1|sgd:S000006385|ensemblfungi:YPR181C(gene)|ensemblfungi:YPR181C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003400"(regulation of COPII vesicle coating)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016236"(macroautophagy)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0061709"(reticulophagy)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:0090110"(COPII-coated vesicle cargo loading)|interpro:IPR006895(Zinc finger, Sec23/Sec24-type)|interpro:IPR006896(Sec23/Sec24 trunk region)|interpro:IPR006900(Sec23/Sec24 helical region)|interpro:IPR007123(Gelsolin region)|interpro:IPR012990(Sec23/Sec24 beta-sandwich)|interpro:IPR029006|interpro:IPR036174|interpro:IPR036175|interpro:IPR036180|interpro:IPR036465|interpro:IPR037364|interpro:IPR037550|rcsb pdb:1M2O|rcsb pdb:2QTV|rcsb pdb:4BZI|rcsb pdb:6GNI|rcsb pdb:6ZGA|reactome:R-SCE-204005|reactome:R-SCE-5694530|reactome:R-SCE-983170|rcsb pdb:1M2V|dip:DIP-2232N|mint:P15303|sgd:YPR181C(identity)	-	-	crc64:69811913848265FB	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:34It0miSDTtv5wwJ+ERHXJzWRiQ9606	rogid:IqC3qOrbef6aMHBztUW5+7DZ4IQ559292	intact-crc:755C4B5B3683823B|rigid:CcnZTitK+IXIqlud5ojOCUOJdcs	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O75477	uniprotkb:P15303	intact:EBI-359299|uniprotkb:B0QZ42|uniprotkb:Q53HV0|ensembl:ENSP00000384900|ensembl:ENSP00000410964|intact:EBI-21351077|uniprotkb:D3DR65	intact:EBI-16584|ensemblfungi:YPR181C|uniprotkb:D6W4I1	psi-mi:erln1_human(display_long)|uniprotkb:KEO4(gene name synonym)|uniprotkb:ERLIN1(gene name)|psi-mi:ERLIN1(display_short)|uniprotkb:C10orf69(gene name synonym)|uniprotkb:KE04(gene name synonym)|uniprotkb:SPFH1(gene name synonym)|uniprotkb:Endoplasmic reticulum lipid raft-associated protein 1(gene name synonym)|uniprotkb:Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 1(gene name synonym)|uniprotkb:Protein KE04(gene name synonym)	psi-mi:sec23_yeast(display_long)|uniprotkb:SEC23(gene name)|psi-mi:SEC23(display_short)|uniprotkb:P9705.14(orf name)|uniprotkb:YPR181C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11538817|imex:IM-24995-1729	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001094096.1|refseq:NP_006450.2|ensembl:ENSG00000107566(gene)|ensembl:ENST00000407654(transcript)|ensembl:ENST00000421367(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032933"(SREBP signaling pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045541"(negative regulation of cholesterol biosynthetic process)|go:"GO:0045717"(negative regulation of fatty acid biosynthetic process)|interpro:IPR001107(Band 7 protein)|interpro:IPR033294|interpro:IPR036013|mint:O75477|reactome:R-HSA-382556|reactome:R-HSA-5678895|refseq:NP_001334786.1|refseq:NP_001334788.1|refseq:NP_001334789.1|refseq:NP_001334790.1|entrezgene/locuslink:10613(identity)	refseq:NP_015507.1|sgd:S000006385|ensemblfungi:YPR181C(gene)|ensemblfungi:YPR181C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003400"(regulation of COPII vesicle coating)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016236"(macroautophagy)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0061709"(reticulophagy)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:0090110"(COPII-coated vesicle cargo loading)|interpro:IPR006895(Zinc finger, Sec23/Sec24-type)|interpro:IPR006896(Sec23/Sec24 trunk region)|interpro:IPR006900(Sec23/Sec24 helical region)|interpro:IPR007123(Gelsolin region)|interpro:IPR012990(Sec23/Sec24 beta-sandwich)|interpro:IPR029006|interpro:IPR036174|interpro:IPR036175|interpro:IPR036180|interpro:IPR036465|interpro:IPR037364|interpro:IPR037550|rcsb pdb:1M2O|rcsb pdb:2QTV|rcsb pdb:4BZI|rcsb pdb:6GNI|rcsb pdb:6ZGA|reactome:R-SCE-204005|reactome:R-SCE-5694530|reactome:R-SCE-983170|rcsb pdb:1M2V|dip:DIP-2232N|mint:P15303|sgd:YPR181C(identity)	-	-	crc64:69811913848265FB	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2019/05/28	rogid:HycFhL5qL5GLmaIIc9NtTcBbu1M9606	rogid:IqC3qOrbef6aMHBztUW5+7DZ4IQ559292	intact-crc:A5E2EAE73D995A06|rigid:uipxd6WuchHbeGrUAlWl4Mm1AYo	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P15202	uniprotkb:Q9ULX6	intact:EBI-4061|uniprotkb:E9P947|uniprotkb:D6VSN6|ensemblfungi:YDR256C	intact:EBI-357530|uniprotkb:O94792|uniprotkb:Q96J58|uniprotkb:Q9NRQ0|uniprotkb:Q9UGM0|uniprotkb:B5BU90|uniprotkb:B4DJ74|ensembl:ENSP00000380557	psi-mi:cata_yeast(display_long)|uniprotkb:YD9320A.06C(orf name)|uniprotkb:YDR256C(locus name)|uniprotkb:CTA1(gene name)|psi-mi:CTA1(display_short)	psi-mi:akp8l_human(display_long)|uniprotkb:AKAP8L(gene name)|psi-mi:AKAP8L(display_short)|uniprotkb:HRIHFB2018(orf name)|uniprotkb:NAKAP95(gene name synonym)|uniprotkb:Neighbor of A-kinase-anchoring protein 95(gene name synonym)|uniprotkb:Homologous to AKAP95 protein(gene name synonym)|uniprotkb:Helicase A-binding protein 95(gene name synonym)|uniprotkb:NAKAP(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11538808|imex:IM-24995-1728	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002664|refseq:NP_010542.1|dip:DIP-4320N|mint:P15202|ensemblfungi:YDR256C(gene)|ensemblfungi:YDR256C_mRNA(transcript)|go:"GO:0000302"(response to reactive oxygen species)|go:"GO:0001315"(age-dependent response to reactive oxygen species)|go:"GO:0004096"(catalase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005777"(peroxisome)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0020037"(heme binding)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0046872"(metal ion binding)|interpro:IPR002226(Catalase)|interpro:IPR010582(Catalase-related)|interpro:IPR011614(Catalase, N-terminal)|interpro:IPR018028|interpro:IPR020835|interpro:IPR024708|interpro:IPR024711|rcsb pdb:1A4E|sgd:YDR256C(identity)	refseq:NP_001278407.1|refseq:NP_055186.3|dip:DIP-27541N|ensembl:ENSG00000011243(gene)|ensembl:ENST00000397410(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010793"(regulation of mRNA export from nucleus)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016605"(PML body)|go:"GO:0016607"(nuclear speck)|go:"GO:0017151"(DEAD/H-box RNA helicase binding)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0033127"(regulation of histone phosphorylation)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0044839"(cell cycle G2/M phase transition)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0051081"(nuclear membrane disassembly)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR007071("A-kinase anchoring protein 95 (AKAP95)")|interpro:IPR034736|mint:Q9ULX6|entrezgene/locuslink:26993(identity)	-	crc64:22DFCC599D79801F	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2018/09/18	rogid:+NMosmB3jzYGleF7X88sJ2qLm/Y559292	rogid:SAs8jxuWxLOiWN/TRyjVvr5m/5Y9606	intact-crc:C23DC899078E2B03|rigid:MQs7mJ+EXKvoppESJeluyw51LxA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P15202	uniprotkb:Q9NRG1	intact:EBI-4061|uniprotkb:E9P947|uniprotkb:D6VSN6|ensemblfungi:YDR256C	intact:EBI-739759|uniprotkb:Q53HA7|uniprotkb:Q59EL9|uniprotkb:Q5VV18|uniprotkb:Q5VV20|uniprotkb:B7Z1Z3|ensembl:ENSP00000318602	psi-mi:cata_yeast(display_long)|uniprotkb:YD9320A.06C(orf name)|uniprotkb:YDR256C(locus name)|uniprotkb:CTA1(gene name)|psi-mi:CTA1(display_short)	psi-mi:prdc1_human(display_long)|uniprotkb:PRTFDC1(gene name)|psi-mi:PRTFDC1(display_short)|uniprotkb:HHGP(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11538799|imex:IM-24995-1727	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002664|refseq:NP_010542.1|dip:DIP-4320N|mint:P15202|ensemblfungi:YDR256C(gene)|ensemblfungi:YDR256C_mRNA(transcript)|go:"GO:0000302"(response to reactive oxygen species)|go:"GO:0001315"(age-dependent response to reactive oxygen species)|go:"GO:0004096"(catalase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005777"(peroxisome)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0020037"(heme binding)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0046872"(metal ion binding)|interpro:IPR002226(Catalase)|interpro:IPR010582(Catalase-related)|interpro:IPR011614(Catalase, N-terminal)|interpro:IPR018028|interpro:IPR020835|interpro:IPR024708|interpro:IPR024711|rcsb pdb:1A4E|sgd:YDR256C(identity)	refseq:NP_001269715.1|refseq:NP_064585.1|ensembl:ENSG00000099256(gene)|ensembl:ENST00000320152(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0006166"(purine ribonucleoside salvage)|go:"GO:0042803"(protein homodimerization activity)|interpro:IPR000836(Phosphoribosyltransferase)|interpro:IPR005904(Hypoxanthine phosphoribosyl transferase)|interpro:IPR029057|rcsb pdb:2JBH|entrezgene/locuslink:56952(identity)	-	crc64:22DFCC599D79801F	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:+NMosmB3jzYGleF7X88sJ2qLm/Y559292	rogid:grTZnSalFILRSeeZBjM1mTtF0xo9606	intact-crc:86CE03D8003EEAE0|rigid:9q7gYQNJc5B+h4/yED4XUFOSjUs	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P14907	uniprotkb:Q8IYF3-3	intact:EBI-12265|uniprotkb:D6VWE3	intact:EBI-11523345|ensembl:ENSP00000363453	psi-mi:nsp1_yeast(display_long)|uniprotkb:NSP1(gene name)|psi-mi:NSP1(display_short)|uniprotkb:YJL041W(locus name)|uniprotkb:J1207(orf name)|uniprotkb:Nuclear pore protein NSP1(gene name synonym)|uniprotkb:Nucleoskeletal-like protein(gene name synonym)|uniprotkb:p110(gene name synonym)	psi-mi:q8iyf3-3(display_long)|uniprotkb:TEX11(gene name)|psi-mi:TEX11(display_short)|uniprotkb:Protein ZIP4 homolog(gene name synonym)|uniprotkb:ZIP4(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11538788|imex:IM-24995-1726	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005643"(nuclear pore)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006409"(tRNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034399"(nuclear periphery)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0044615"(nuclear pore nuclear basket)|go:"GO:0097064"(ncRNA export from nucleus)|interpro:IPR007758(Nucleoporin, Nsp1-like, C-terminal)|interpro:IPR026010|rcsb pdb:1O6O|refseq:NP_012494.3|sgd:S000003577|mint:P14907|dip:DIP-1484N|sgd:YJL041W(identity)	ensembl:ENSG00000120498(gene)|ensembl:ENST00000374333(transcript)|intact:EBI-742397(isoform-parent)|uniprotkb:Q8IYF3-3(isoform-parent)|entrezgene/locuslink:56159(identity)	-	crc64:A258003CB1917810	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:wFdC6D8JzkhJpF+k3qtnFj9+4pA559292	rogid:PUAMFmnm5ZV2rnJ1rhm9ZeRCixg9606	intact-crc:DFCABF6E37242D2D|rigid:Vos9JzohYWyh3B2VJRQIX3CQZAE	false	-	sufficient binding region:9-925	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P15732	uniprotkb:Q9HCM9-2	intact:EBI-2097669|uniprotkb:D6VS45|ensemblfungi:YDR059C	intact:EBI-11523450|ensembl:ENSP00000365847|ensembl:ENSP00000373095|ensembl:ENSP00000373097|ensembl:ENSP00000379797|ensembl:ENSP00000379800|ensembl:ENSP00000383486|ensembl:ENSP00000387445|ensembl:ENSP00000389198|ensembl:ENSP00000389852|ensembl:ENSP00000392130|ensembl:ENSP00000394353|ensembl:ENSP00000396986|ensembl:ENSP00000398956|ensembl:ENSP00000401071|ensembl:ENSP00000401184|ensembl:ENSP00000404340|ensembl:ENSP00000404904|ensembl:ENSP00000411582|ensembl:ENSP00000412743|ensembl:ENSP00000414525|ensembl:ENSP00000415259	psi-mi:ubc5_yeast(display_long)|uniprotkb:UBC5(gene name)|psi-mi:UBC5(display_short)|uniprotkb:Ubiquitin-protein ligase(gene name synonym)|uniprotkb:Ubiquitin carrier protein(gene name synonym)|uniprotkb:YD9609.13C(orf name)|uniprotkb:D4234(orf name)|uniprotkb:YDR059C(locus name)|uniprotkb:E2 ubiquitin-conjugating enzyme 5(gene name synonym)	psi-mi:q9hcm9-2(display_long)|uniprotkb:TRIM39(gene name)|psi-mi:TRIM39(display_short)|uniprotkb:RING finger protein 23(gene name synonym)|uniprotkb:RNF23(gene name synonym)|uniprotkb:TFP(gene name synonym)|uniprotkb:Testis-abundant finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 39(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM39(gene name synonym)|uniprotkb:TIM39beta(isoform synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11538889|imex:IM-24995-1737	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010344.1|sgd:S000002466|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR023313|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|mint:P15732|ensemblfungi:YDR059C(gene)|ensemblfungi:YDR059C_mRNA(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034605"(cellular response to heat)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070628"(proteasome binding)|reactome:R-SCE-8866652|reactome:R-SCE-8866654|reactome:R-SCE-9033241|reactome:R-SCE-983168|sgd:YDR059C(identity)	intact:EBI-739510(isoform-parent)|ensembl:ENSG00000204599(gene)|ensembl:ENSG00000206495(gene)|ensembl:ENSG00000224994(gene)|ensembl:ENSG00000226437(gene)|ensembl:ENSG00000229929(gene)|ensembl:ENSG00000230308(gene)|ensembl:ENSG00000232839(gene)|ensembl:ENST00000376659(transcript)|ensembl:ENST00000383601(transcript)|ensembl:ENST00000383603(transcript)|ensembl:ENST00000396548(transcript)|ensembl:ENST00000396551(transcript)|ensembl:ENST00000400644(transcript)|ensembl:ENST00000414015(transcript)|ensembl:ENST00000419790(transcript)|ensembl:ENST00000430502(transcript)|ensembl:ENST00000431272(transcript)|ensembl:ENST00000433900(transcript)|ensembl:ENST00000438076(transcript)|ensembl:ENST00000438859(transcript)|ensembl:ENST00000440117(transcript)|ensembl:ENST00000443109(transcript)|ensembl:ENST00000446397(transcript)|ensembl:ENST00000449318(transcript)|ensembl:ENST00000450778(transcript)|ensembl:ENST00000451132(transcript)|ensembl:ENST00000452705(transcript)|ensembl:ENST00000458607(transcript)|uniprotkb:Q9HCM9-2(isoform-parent)|entrezgene/locuslink:56658(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:lhkS9orGIZV1O+L0mEfzlpRvgtk559292	rogid:UfSn2+IVRxtGomVeDGdZpL7mz5I9606	intact-crc:D9D8AA493D161A3C|rigid:P6Z55egYY1Vj8JOem5y9wSpIWKA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P14373	uniprotkb:P15705	intact:EBI-719493|uniprotkb:A2BE15|uniprotkb:Q5RJA8|uniprotkb:Q5ST26|uniprotkb:Q6LA73|uniprotkb:Q6NXR9|uniprotkb:Q9BZY6|uniprotkb:Q9UJL3|ensembl:ENSP00000383555|ensembl:ENSP00000392787|ensembl:ENSP00000405229|ensembl:ENSP00000414793|ensembl:ENSP00000366404	intact:EBI-18418|uniprotkb:D6W293|ensemblfungi:YOR027W	psi-mi:tri27_human(display_long)|uniprotkb:TRIM27(gene name)|psi-mi:TRIM27(display_short)|uniprotkb:RNF76(gene name synonym)|uniprotkb:RFP(gene name synonym)|uniprotkb:Ret finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 27(gene name synonym)|uniprotkb:RING finger protein 76(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM27(gene name synonym)	psi-mi:sti1_yeast(display_long)|uniprotkb:STI1(gene name)|psi-mi:STI1(display_short)|uniprotkb:OR26.17(orf name)|uniprotkb:YOR027W(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11538880|imex:IM-24995-1736	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006501.1|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0090281"(negative regulation of calcium ion import)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR020457|interpro:IPR035791|interpro:IPR043136|mint:P14373|reactome:R-HSA-3232142|reactome:R-HSA-9635465|reactome:R-HSA-8948751|ensembl:ENSG00000204713(gene)|ensembl:ENSG00000215641(gene)|ensembl:ENSG00000229006(gene)|ensembl:ENSG00000234495(gene)|ensembl:ENSG00000237071(gene)|ensembl:ENST00000377199(transcript)|ensembl:ENST00000400720(transcript)|ensembl:ENST00000431123(transcript)|ensembl:ENST00000435528(transcript)|ensembl:ENST00000437160(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001650"(fibrillar center)|go:"GO:0002820"(negative regulation of adaptive immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|entrezgene/locuslink:5987(identity)	refseq:NP_014670.1|sgd:S000005553|ensemblfungi:YOR027W(gene)|ensemblfungi:YOR027W_mRNA(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0008104"(protein localization)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0042030"(ATPase inhibitor activity)|go:"GO:0051879"(Hsp90 protein binding)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR041243|rcsb pdb:2LLV|rcsb pdb:2LLW|rcsb pdb:3UPV|rcsb pdb:3UQ3|reactome:R-SCE-3371497|reactome:R-SCE-9696273|dip:DIP-2329N|mint:P15705|sgd:YOR027W(identity)	-	-	crc64:CF8A85C2BBD3C44C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:dsfH5OUghD8KSaTz1SFw9OYVTK49606	rogid:+w2ibiXXPwvtcC3RxknGi0ELvvE559292	intact-crc:7EAEBEEC680C8972|rigid:/0f+kHMDtL8MhCjXJzxLlnLTMwo	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P15646	uniprotkb:Q16637	intact:EBI-6838|uniprotkb:P89890|uniprotkb:D6VRX5|ensemblfungi:YDL014W	intact:EBI-395421|uniprotkb:Q13119|uniprotkb:Q549U5|uniprotkb:Q96J51|ensembl:ENSP00000305857|uniprotkb:A8K0V4|ensembl:ENSP00000370083|ensembl:ENSP00000370117|ensembl:ENSP00000370119|ensembl:ENSP00000479920|ensembl:ENSP00000482966|ensembl:ENSP00000483515|ensembl:ENSP00000483819|ensembl:ENSP00000487206|ensembl:ENSP00000487421	psi-mi:fbrl_yeast(display_long)|uniprotkb:NOP1(gene name)|psi-mi:NOP1(display_short)|uniprotkb:LOT3(gene name synonym)|uniprotkb:YDL014W(locus name)|uniprotkb:D2870(orf name)|uniprotkb:U3 small nucleolar RNA-associated protein NOP1(gene name synonym)|uniprotkb:Histone-glutamine methyltransferase(gene name synonym)	psi-mi:smn_human(display_long)|uniprotkb:SMN1(gene name)|psi-mi:SMN1(display_short)|uniprotkb:SMN(gene name synonym)|uniprotkb:SMNT(gene name synonym)|uniprotkb:SMN2(gene name)|psi-mi:SMN2(display_short)|uniprotkb:SMNC(gene name synonym)|uniprotkb:Component of gems 1(gene name synonym)|uniprotkb:Gemin-1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11538871|imex:IM-24995-1735	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010270.1|sgd:S000002172|mint:P15646|dip:DIP-698N|ensemblfungi:YDL014W(gene)|ensemblfungi:YDL014W_mRNA(transcript)|go:"GO:0000451"(rRNA 2'-O-methylation)|go:"GO:0000494"(box C/D RNA 3'-end processing)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006356"(regulation of transcription by RNA polymerase I)|go:"GO:0006364"(rRNA processing)|go:"GO:0008171"(O-methyltransferase activity)|go:"GO:0008649"(rRNA methyltransferase activity)|go:"GO:0030686"(90S preribosome)|go:"GO:0031167"(rRNA methylation)|go:"GO:0031428"(box C/D RNP complex)|go:"GO:0032040"(small-subunit processome)|go:"GO:0043144"("sno(s)RNA processing")|go:"GO:1990258"(histone glutamine methylation)|go:"GO:1990259"(histone-glutamine methyltransferase activity)|interpro:IPR000692(Fibrillarin)|interpro:IPR020813|interpro:IPR029063|rcsb pdb:5WLC|rcsb pdb:5WYJ|rcsb pdb:5WYK|rcsb pdb:6KE6|rcsb pdb:6LQP|rcsb pdb:6LQQ|rcsb pdb:6LQR|rcsb pdb:6LQS|rcsb pdb:6LQT|rcsb pdb:6LQU|rcsb pdb:6LQV|rcsb pdb:6ND4|rcsb pdb:6ZDT|rcsb pdb:6ZQA|rcsb pdb:6ZQB|rcsb pdb:6ZQC|rcsb pdb:6ZQD|rcsb pdb:6ZQE|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-6791226|sgd:YDL014W(identity)	refseq:NP_000335.1|refseq:NP_059107.1|refseq:NP_075012.1|refseq:NP_075013.1|refseq:NP_075014.1|refseq:NP_075015.1|ensembl:ENSG00000172062(gene)|ensembl:ENSG00000205571(gene)|ensembl:ENSG00000273772(gene)|ensembl:ENSG00000275349(gene)|ensembl:ENSG00000277773(gene)|ensembl:ENST00000351205(transcript)|ensembl:ENST00000380707(transcript)|ensembl:ENST00000380741(transcript)|ensembl:ENST00000380743(transcript)|ensembl:ENST00000614610(transcript)|ensembl:ENST00000618251(transcript)|ensembl:ENST00000618661(transcript)|ensembl:ENST00000622739(transcript)|ensembl:ENST00000627341(transcript)|ensembl:ENST00000629122(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0007399"(nervous system development)|go:"GO:0015030"(Cajal body)|go:"GO:0016604"(nuclear body)|go:"GO:0030018"(Z disc)|go:"GO:0030424"(axon)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043204"(perikaryon)|go:"GO:0097504"(Gemini of coiled bodies)|interpro:IPR002999(Tudor)|interpro:IPR010304(Survival motor neuron)|mint:Q16637|rcsb pdb:1G5V|rcsb pdb:1MHN|rcsb pdb:2LEH|rcsb pdb:4A4E|rcsb pdb:4A4G|rcsb pdb:4GLI|rcsb pdb:4QQ6|rcsb pdb:5XJL|go:"GO:0034719"(SMN-Sm protein complex)|rcsb pdb:5XJQ|rcsb pdb:5XJR|rcsb pdb:5XJS|rcsb pdb:5XJT|rcsb pdb:5XJU|reactome:R-HSA-191859|go:"GO:0032797"(SMN complex)|refseq:NP_001284644.1|ensembl:ENSP00000305857|ensembl:ENSP00000370083|ensembl:ENSP00000370117|ensembl:ENST00000380742|ensembl:ENSP00000370118|ensembl:ENSP00000370119|ensembl:ENST00000503079|ensembl:ENSP00000428128|ensembl:ENST00000506163|ensembl:ENSP00000424926|ensembl:ENST00000611442|ensembl:ENSP00000483768|ensembl:ENST00000614240|ensembl:ENSP00000479279|ensembl:ENSP00000479920|ensembl:ENST00000614773|ensembl:ENSP00000481427|ensembl:ENSP00000483515|ensembl:ENSP00000483819|ensembl:ENST00000622158|ensembl:ENSP00000480906|ensembl:ENSP00000482966|ensembl:ENST00000624634|ensembl:ENSP00000485595|ensembl:ENST00000626847|ensembl:ENSP00000486152|ensembl:ENSP00000487421|ensembl:ENST00000628353|ensembl:ENSP00000487029|ensembl:ENST00000628642|ensembl:ENSP00000487015|ensembl:ENSP00000487206|refseq:XP_016865275.1|dip:DIP-31309N|entrezgene/locuslink:6607(identity)	-	crc64:56A8B958A7B6066E	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:zc81RbHf8PxId/8oPXPD3/MpmBU559292	rogid:QGivm7E8suciCWXO4l0zCUzCl2g9606	intact-crc:C99D4EA845611408|rigid:lM0zfvKUz7wkBKJV2PFPNPJ+goI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9HD26-2	uniprotkb:P15625	intact:EBI-11102276|ensembl:ENSP00000052569	intact:EBI-18678|uniprotkb:D6VTK8|ensemblfungi:YFL022C	psi-mi:q9hd26-2(display_long)|uniprotkb:GOPC(gene name)|psi-mi:GOPC(display_short)|uniprotkb:CAL(gene name synonym)|uniprotkb:CFTR-associated ligand(gene name synonym)|uniprotkb:FIG(gene name synonym)|uniprotkb:Fused in glioblastoma(gene name synonym)|uniprotkb:PDZ protein interacting specifically with TC10(gene name synonym)	psi-mi:syfa_yeast(display_long)|uniprotkb:FRS2(gene name)|psi-mi:FRS2(display_short)|uniprotkb:Phenylalanyl-tRNA synthetase alpha subunit(gene name synonym)|uniprotkb:YFL022C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11538862|imex:IM-24995-1734	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000047932(gene)|ensembl:ENST00000052569(transcript)|intact:EBI-349832(isoform-parent)|uniprotkb:Q9HD26-2(isoform-parent)|entrezgene/locuslink:57120(identity)	refseq:NP_116631.1|sgd:S000001872|ensemblfungi:YFL022C(gene)|ensemblfungi:YFL022C_mRNA(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0002161"(aminoacyl-tRNA editing activity)|go:"GO:0004826"(phenylalanine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006432"(phenylalanyl-tRNA aminoacylation)|go:"GO:0009328"(phenylalanine-tRNA ligase complex)|interpro:IPR002319(Phenylalanyl-tRNA synthetase, class IIc)|interpro:IPR004529(Phenylalanyl-tRNA synthetase, class IIc, alpha subunit)|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR040586|interpro:IPR040725|dip:DIP-5428N|mint:P15625|sgd:YFL022C(identity)	-	-	crc64:50B7EAC675AB559B	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:QoEGY54FfmwTrpGVMQN9ASGPgVI9606	rogid:hOEtrjcfIHQLY9FwCDb3XI593A4559292	intact-crc:6B0785CD05917C91|rigid:srErfDzAAmIU+g7YaBH+fja4yiM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P15625	uniprotkb:O15162	intact:EBI-18678|uniprotkb:D6VTK8|ensemblfungi:YFL022C	intact:EBI-740019|ensembl:ENSP00000345494|uniprotkb:B2R8H8|uniprotkb:B4DTE8	psi-mi:syfa_yeast(display_long)|uniprotkb:FRS2(gene name)|psi-mi:FRS2(display_short)|uniprotkb:Phenylalanyl-tRNA synthetase alpha subunit(gene name synonym)|uniprotkb:YFL022C(locus name)	psi-mi:pls1_human(display_long)|uniprotkb:PLSCR1(gene name)|psi-mi:PLSCR1(display_short)|uniprotkb:"Ca(2+)-dependent phospholipid scramblase 1"(gene name synonym)|uniprotkb:Erythrocyte phospholipid scramblase(gene name synonym)|uniprotkb:MmTRA1b(gene name synonym)|uniprotkb:"Mg(2+)-dependent nuclease"(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11538853|imex:IM-24995-1733	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_116631.1|sgd:S000001872|ensemblfungi:YFL022C(gene)|ensemblfungi:YFL022C_mRNA(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0002161"(aminoacyl-tRNA editing activity)|go:"GO:0004826"(phenylalanine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006432"(phenylalanyl-tRNA aminoacylation)|go:"GO:0009328"(phenylalanine-tRNA ligase complex)|interpro:IPR002319(Phenylalanyl-tRNA synthetase, class IIc)|interpro:IPR004529(Phenylalanyl-tRNA synthetase, class IIc, alpha subunit)|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR040586|interpro:IPR040725|dip:DIP-5428N|mint:P15625|sgd:YFL022C(identity)	ensembl:ENSG00000188313(gene)|ensembl:ENST00000342435(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001618"(virus receptor activity)|go:"GO:0003677"(DNA binding)|go:"GO:0004518"(nuclease activity)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006659"(phosphatidylserine biosynthetic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0006953"(acute-phase response)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010288"(response to lead ion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0017121"(plasma membrane phospholipid scrambling)|go:"GO:0017124"(SH3 domain binding)|ensembl:ENSP00000345494|ensembl:ENST00000448787|ensembl:ENSP00000411675|refseq:NP_066928.1|go:"GO:0017128"(phospholipid scramblase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030168"(platelet activation)|go:"GO:0032791"(lead ion binding)|go:"GO:0033003"(regulation of mast cell activation)|go:"GO:0035456"(response to interferon-beta)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0045340"(mercury ion binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0051607"(defense response to virus)|go:"GO:0060368"(regulation of Fc receptor mediated stimulatory signaling pathway)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070782"(phosphatidylserine exposure on apoptotic cell surface)|go:"GO:1905820"(positive regulation of chromosome separation)|go:"GO:2000373"("positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity")|interpro:IPR005552(Scramblase)|mint:O15162|rcsb pdb:1Y2A|refseq:XP_011511209.1|refseq:XP_011511206.1|refseq:XP_005247595.1|refseq:XP_011511208.1|refseq:XP_016862118.1|entrezgene/locuslink:5359(identity)	-	crc64:50B7EAC675AB559B	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:hOEtrjcfIHQLY9FwCDb3XI593A4559292	rogid:XudfvUkrZbB28t9tpFkokgnDFGc9606	intact-crc:2467CD2A5B9B04AD|rigid:7WyGodAFnXD8EApEF8VHsdlfy+A	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P15365	uniprotkb:Q969F0	intact:EBI-5527|uniprotkb:D6VWX1|ensemblfungi:YJR152W	intact:EBI-743099|ensembl:ENSP00000359375	psi-mi:dal5_yeast(display_long)|uniprotkb:DAL5(gene name)|psi-mi:DAL5(display_short)|uniprotkb:UREP1(gene name synonym)|uniprotkb:YJR152W(locus name)|uniprotkb:J2230(orf name)	psi-mi:fate1_human(display_long)|uniprotkb:Tumor antigen BJ-HCC-2(gene name synonym)|uniprotkb:Cancer/testis antigen 43(gene name synonym)|uniprotkb:FATE1(gene name)|psi-mi:FATE1(display_short)|uniprotkb:FATE(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11538844|imex:IM-24995-1732	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003913|refseq:NP_012686.3|dip:DIP-7873N|mint:P15365|ensemblfungi:YJR152W(gene)|ensemblfungi:YJR152W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0015124"(allantoate transmembrane transporter activity)|go:"GO:0015719"(allantoate transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0031224"(intrinsic component of membrane)|go:"GO:0042938"(dipeptide transport)|go:"GO:0042939"(tripeptide transport)|go:"GO:0071916"(dipeptide transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR036259|sgd:YJR152W(identity)	refseq:NP_149076.1|ensembl:ENSG00000147378(gene)|ensembl:ENST00000370350(transcript)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|go:"GO:0051562"(negative regulation of mitochondrial calcium ion concentration)|interpro:IPR039153|interpro:IPR039433|mint:Q969F0|entrezgene/locuslink:89885(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Y2kCv3dK4Hjn9hJpK+WK5rp6VKU559292	rogid:Nm1N6lO92MHr5rIKC007oouF5RE9606	intact-crc:9883C080DF7D5AFD|rigid:RD0RDUauwGS/643juHawjhQo/4A	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P30260-2	uniprotkb:P15873	intact:EBI-11523497|ensembl:ENSP00000434614	intact:EBI-12993|uniprotkb:D6VQ89|ensemblfungi:YBR088C	psi-mi:p30260-2(display_long)|uniprotkb:CDC27(gene name)|psi-mi:CDC27(display_short)|uniprotkb:ANAPC3(gene name synonym)|uniprotkb:Anaphase-promoting complex subunit 3(gene name synonym)|uniprotkb:CDC27 homolog(gene name synonym)|uniprotkb:D0S1430E(gene name synonym)|uniprotkb:D17S978E(gene name synonym)|uniprotkb:H-NUC(gene name synonym)	psi-mi:pcna_yeast(display_long)|uniprotkb:YBR0811(orf name)|uniprotkb:YBR088C(locus name)|uniprotkb:POL30(gene name)|psi-mi:POL30(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11538930|imex:IM-24995-1741	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000004897(gene)|ensembl:ENST00000531206(transcript)|intact:EBI-994813(isoform-parent)|entrezgene/locuslink:996(identity)	refseq:NP_009645.1|sgd:S000000292|go:"GO:0043626"(PCNA complex)|go:"GO:0070987"(error-free translesion synthesis)|go:"GO:1902394"(positive regulation of exodeoxyribonuclease activity)|go:"GO:1903022"(positive regulation of phosphodiesterase activity, acting on 3'-phosphoglycolate-terminated DNA strands)|go:"GO:1905779"(positive regulation of exonuclease activity)|interpro:IPR000730(Proliferating cell nuclear antigen, PCNA)|interpro:IPR022648|interpro:IPR022649|interpro:IPR022659|rcsb pdb:1PLQ|rcsb pdb:1PLR|rcsb pdb:1SXJ|rcsb pdb:2OD8|rcsb pdb:3F1W|rcsb pdb:3GPM|rcsb pdb:3GPN|rcsb pdb:3L0W|rcsb pdb:4L6P|rcsb pdb:3L0X|rcsb pdb:3L10|rcsb pdb:4YHR|rcsb pdb:3PGE|rcsb pdb:3V60|rcsb pdb:3V61|rcsb pdb:3V62|rcsb pdb:5JNE|rcsb pdb:4L60|mint:P15873|dip:DIP-2417N|go:"GO:0035753"(maintenance of DNA trinucleotide repeats)|ensemblfungi:YBR088C(gene)|ensemblfungi:YBR088C_mRNA(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000710"(meiotic mismatch repair)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005657"(replication fork)|go:"GO:0006272"(leading strand elongation)|go:"GO:0006273"(lagging strand elongation)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006298"(mismatch repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0006348"|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0019985"(translesion synthesis)|go:"GO:0030337"(DNA polymerase processivity factor activity)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0034087"(establishment of mitotic sister chromatid cohesion)|go:"GO:0042802"(identical protein binding)|rcsb pdb:5T9D|rcsb pdb:5V7K|rcsb pdb:5V7M|rcsb pdb:5ZUT|rcsb pdb:6CX2|rcsb pdb:6CX3|rcsb pdb:6CX4|rcsb pdb:6D0Q|rcsb pdb:6D0R|rcsb pdb:6E49|rcsb pdb:6W9W|rcsb pdb:6WAC|reactome:R-SCE-110312|reactome:R-SCE-110320|reactome:R-SCE-4615885|reactome:R-SCE-5358565|reactome:R-SCE-5655862|reactome:R-SCE-5656121|reactome:R-SCE-5656169|reactome:R-SCE-6782135|reactome:R-SCE-69091|reactome:R-SCE-69166|reactome:R-SCE-69183|reactome:R-SCE-8866654|rcsb pdb:5V7L|sgd:YBR088C(identity)	-	isoform-comment:No experimental confirmation available. May be due to competing acceptor splice site.	crc64:9B56C5851621DDDC	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:/GhmGv1GqwYuwjZWyCXHEd5UN3M9606	rogid:/+XSPV99OBBwBBC/nY0JiHaAeSI559292	intact-crc:4C5F30100B6F7C4A|rigid:4EM3yzg8PzpDhnm9KhYccsP8+yo	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8N0S2	uniprotkb:P15807	intact:EBI-6872807|ensembl:ENSP00000341282|uniprotkb:Q9BWU4|uniprotkb:B2RC80|uniprotkb:Q9BWU3	intact:EBI-10770|ensemblfungi:YBR213W|uniprotkb:D6VQK9	psi-mi:syce1_human(display_long)|uniprotkb:C10orf94(gene name synonym)|uniprotkb:Cancer/testis antigen 76(gene name synonym)|uniprotkb:SYCE1(gene name)|psi-mi:SYCE1(display_short)	psi-mi:met8_yeast(display_long)|uniprotkb:YBR1461(orf name)|uniprotkb:YBR213W(locus name)|uniprotkb:MET8(gene name)|psi-mi:MET8(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11538919|imex:IM-24995-1740	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000171772(gene)|ensembl:ENST00000343131(transcript)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0000801"(central element)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051301"(cell division)|interpro:IPR026676|reactome:R-HSA-1221632|refseq:NP_001137235.1|refseq:NP_570140.1|entrezgene/locuslink:93426(identity)	ensemblfungi:YBR213W(gene)|ensemblfungi:YBR213W_mRNA(transcript)|go:"GO:0000103"(sulfate assimilation)|go:"GO:0004325"(ferrochelatase activity)|go:"GO:0019354"(siroheme biosynthetic process)|go:"GO:0043115"(precorrin-2 dehydrogenase activity)|go:"GO:0051266"(sirohydrochlorin ferrochelatase activity)|interpro:IPR028161|interpro:IPR028162|interpro:IPR028281|interpro:IPR036291|rcsb pdb:1KYQ|refseq:NP_009772.1|sgd:S000000417|mint:P15807|dip:DIP-4944N|sgd:YBR213W(identity)	-	-	crc64:0EE9A6DE8A43673E	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:qLVqIlFiwZJHFfoyYXV3jrqdd609606	rogid:4Z2yZage0Yi6KB2YM/gANFSLcC0559292	intact-crc:F0226554FCE969EA|rigid:hD30oL8Wp0apbcFpk6VS7i9/3u4	false	sufficient binding region:37-351	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P15732	uniprotkb:Q9Y4K3	intact:EBI-2097669|uniprotkb:D6VS45|ensemblfungi:YDR059C	intact:EBI-359276|uniprotkb:Q8NEH5|uniprotkb:A6NKI7|uniprotkb:A8KAB3|ensembl:ENSP00000337853|ensembl:ENSP00000433623|uniprotkb:D3DR16	psi-mi:ubc5_yeast(display_long)|uniprotkb:UBC5(gene name)|psi-mi:UBC5(display_short)|uniprotkb:Ubiquitin-protein ligase(gene name synonym)|uniprotkb:Ubiquitin carrier protein(gene name synonym)|uniprotkb:YD9609.13C(orf name)|uniprotkb:D4234(orf name)|uniprotkb:YDR059C(locus name)|uniprotkb:E2 ubiquitin-conjugating enzyme 5(gene name synonym)	psi-mi:traf6_human(display_long)|uniprotkb:TRAF6(gene name)|psi-mi:TRAF6(display_short)|uniprotkb:RNF85(gene name synonym)|uniprotkb:Interleukin-1 signal transducer(gene name synonym)|uniprotkb:RING finger protein 85(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase TRAF6(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRAF6(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11538910|imex:IM-24995-1739	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010344.1|sgd:S000002466|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR023313|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|mint:P15732|ensemblfungi:YDR059C(gene)|ensemblfungi:YDR059C_mRNA(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034605"(cellular response to heat)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070628"(proteasome binding)|reactome:R-SCE-8866652|reactome:R-SCE-8866654|reactome:R-SCE-9033241|reactome:R-SCE-983168|sgd:YDR059C(identity)	refseq:NP_004611.1|refseq:NP_665802.1|ensembl:ENSG00000175104(gene)|ensembl:ENST00000348124(transcript)|ensembl:ENST00000526995(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001503"(ossification)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001843"(neural tube closure)|go:"GO:0002223"(stimulatory C-type lectin receptor signaling pathway)|go:"GO:0002637"(regulation of immunoglobulin production)|go:"GO:0002726"(positive regulation of T cell cytokine production)|go:"GO:0002753"(cytoplasmic pattern recognition receptor signaling pathway)|go:"GO:0002755"(MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007254"(JNK cascade)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030316"(osteoclast differentiation)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031666"(positive regulation of lipopolysaccharide-mediated signaling pathway)|go:"GO:0031996"(thioesterase binding)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035631"(CD40 receptor complex)|go:"GO:0038095"(Fc-epsilon receptor signaling pathway)|go:"GO:0042088"(T-helper 1 type immune response)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043011"(myeloid dendritic cell differentiation)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0045453"(bone resorption)|go:"GO:0045672"(positive regulation of osteoclast differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048468"(cell development)|go:"GO:0032813"(tumor necrosis factor receptor superfamily binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051865"(protein autoubiquitination)|interpro:IPR012227(TNF receptor-associated factor TRAF)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR027139|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070498"(interleukin-1-mediated signaling pathway)|interpro:IPR037309|interpro:IPR041310|interpro:IPR043211|mint:Q9Y4K3|rcsb pdb:1LB4|rcsb pdb:1LB5|go:"GO:0070534"(protein K63-linked ubiquitination)|rcsb pdb:1LB6|rcsb pdb:2ECI|rcsb pdb:2JMD|rcsb pdb:3HCS|rcsb pdb:3HCT|rcsb pdb:3HCU|rcsb pdb:4Z8M|rcsb pdb:5ZUJ|rcsb pdb:6A33|go:"GO:0070555"(response to interleukin-1)|rcsb pdb:7L3L|reactome:R-HSA-1257604|reactome:R-HSA-166058|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-205043|go:"GO:0071222"(cellular response to lipopolysaccharide)|reactome:R-HSA-209543|reactome:R-HSA-209560|reactome:R-HSA-2871837|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0097400"(interleukin-17-mediated signaling pathway)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1904996"(positive regulation of leukocyte adhesion to vascular endothelial cell)|go:"GO:2000679"(positive regulation of transcription regulatory region DNA binding)|interpro:IPR001293(Zinc finger, TRAF-type)|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-5607764|reactome:R-HSA-5689880|reactome:R-HSA-5689896|reactome:R-HSA-6811558|reactome:R-HSA-9014325|reactome:R-HSA-9020702|reactome:R-HSA-933541|reactome:R-HSA-933542|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-937042|reactome:R-HSA-937072|reactome:R-HSA-9645460|reactome:R-HSA-975110|reactome:R-HSA-975138|reactome:R-HSA-975144|reactome:R-HSA-975155|reactome:R-HSA-975163|reactome:R-HSA-975871|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|dip:DIP-27515N|entrezgene/locuslink:7189(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:lhkS9orGIZV1O+L0mEfzlpRvgtk559292	rogid:m0TTXwlrtXnnjXWbg0MsEULlq0I9606	intact-crc:784646824A7E8D52|rigid:WyHHVlaKokHfqjsp56sg2/L1Sg8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P15732	uniprotkb:Q9UJV3-2	intact:EBI-2097669|uniprotkb:D6VS45|ensemblfungi:YDR059C	intact:EBI-10172526|ensembl:ENSP00000413976	psi-mi:ubc5_yeast(display_long)|uniprotkb:UBC5(gene name)|psi-mi:UBC5(display_short)|uniprotkb:Ubiquitin-protein ligase(gene name synonym)|uniprotkb:Ubiquitin carrier protein(gene name synonym)|uniprotkb:YD9609.13C(orf name)|uniprotkb:D4234(orf name)|uniprotkb:YDR059C(locus name)|uniprotkb:E2 ubiquitin-conjugating enzyme 5(gene name synonym)	psi-mi:q9ujv3-2(display_long)|uniprotkb:RING-type E3 ubiquitin transferase MID2(gene name synonym)|uniprotkb:FXY2(gene name synonym)|uniprotkb:Midin-2(gene name synonym)|uniprotkb:Midline defect 2(gene name synonym)|uniprotkb:Midline-2(gene name synonym)|uniprotkb:RING finger protein 60(gene name synonym)|uniprotkb:RNF60(gene name synonym)|uniprotkb:TRIM1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 1(gene name synonym)|uniprotkb:MID2(gene name)|psi-mi:MID2(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11538899|imex:IM-24995-1738	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010344.1|sgd:S000002466|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR023313|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|mint:P15732|ensemblfungi:YDR059C(gene)|ensemblfungi:YDR059C_mRNA(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034605"(cellular response to heat)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070628"(proteasome binding)|reactome:R-SCE-8866652|reactome:R-SCE-8866654|reactome:R-SCE-9033241|reactome:R-SCE-983168|sgd:YDR059C(identity)	intact:EBI-751983(isoform-parent)|uniprotkb:Q9UJV3-2(isoform-parent)|ensembl:ENSG00000080561(gene)|ensembl:ENST00000443968(transcript)|entrezgene/locuslink:11043(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:lhkS9orGIZV1O+L0mEfzlpRvgtk559292	rogid:/FJ+V2H7SaWon7caUWkEkmHFVxQ9606	intact-crc:24214ECA9731459F|rigid:7Oh3b3p86ZEAyVjJqseGj5X4AeE	false	-	sufficient binding region:21-705	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P16622	uniprotkb:Q13554-3	intact:EBI-8261|uniprotkb:D6W2N2|ensemblfungi:YOR176W	intact:EBI-11523526|ensembl:ENSP00000351542	psi-mi:hemh_yeast(display_long)|uniprotkb:YOR176W(locus name)|uniprotkb:HEM15(gene name)|psi-mi:HEM15(display_short)|uniprotkb:Protoheme ferro-lyase(gene name synonym)|uniprotkb:Heme synthase(gene name synonym)	psi-mi:q13554-3(display_long)|uniprotkb:CAMK2B(gene name)|psi-mi:CAMK2B(display_short)|uniprotkb:CAM2(gene name synonym)|uniprotkb:CAMK2(gene name synonym)|uniprotkb:CAMKB(gene name synonym)|uniprotkb:Beta'E(isoform synonym)|uniprotkb:Beta1(isoform synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11538957|imex:IM-24995-1744	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005702|reactome:R-SCE-189451|refseq:NP_014819.3|dip:DIP-4133N|ensemblfungi:YOR176W(gene)|ensemblfungi:YOR176W_mRNA(transcript)|go:"GO:0004325"(ferrochelatase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006783"(heme biosynthetic process)|interpro:IPR001015(Ferrochelatase)|interpro:IPR019772|interpro:IPR033644|interpro:IPR033659|rcsb pdb:1L8X|rcsb pdb:1LBQ|sgd:YOR176W(identity)	ensembl:ENSG00000058404(gene)|ensembl:ENST00000358707(transcript)|intact:EBI-1058722(isoform-parent)|uniprotkb:Q13554-3(isoform-parent)|entrezgene/locuslink:816(identity)	-	crc64:F04E7C7AAD36C24F	isoform-comment:"Ref.1 (AAD42036) sequence is in conflict in position: 316:A->V."	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:XIsqmtBuj9oH1aN0DT4zEfQ7u9Q559292	rogid:H/SPSRbW/NRcHPJs7Z2y6ESTrhM9606	intact-crc:11EAB22EF9D2C2E0|rigid:N6Dnldxy/SX+NigiURwyH6sVW3M	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9NYB9-2	uniprotkb:P16523	intact:EBI-11096309|ensembl:ENSP00000261017	intact:EBI-10736|ensemblfungi:YNL210W|uniprotkb:D6W0Y0	psi-mi:q9nyb9-2(display_long)|uniprotkb:ABI2(gene name)|psi-mi:ABI2(display_short)|uniprotkb:ARGBPIA(gene name synonym)|uniprotkb:Abelson interactor 2(gene name synonym)|uniprotkb:Abl-binding protein 3(gene name synonym)|uniprotkb:Arg-binding protein 1(gene name synonym)	psi-mi:mer1_yeast(display_long)|uniprotkb:N1330(orf name)|uniprotkb:YNL210W(locus name)|uniprotkb:MER1(gene name)|psi-mi:MER1(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11538948|imex:IM-24995-1743	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-743598(isoform-parent)|ensembl:ENSG00000138443(gene)|ensembl:ENST00000261017(transcript)|uniprotkb:Q9NYB9-2(isoform-parent)|entrezgene/locuslink:10152(identity)	ensemblfungi:YNL210W(gene)|ensemblfungi:YNL210W_mRNA(transcript)|go:"GO:0000280"(nuclear division)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005844"(polysome)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:1990446"(U1 snRNP binding)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR036612|refseq:NP_014189.1|sgd:S000005154|dip:DIP-1436N|sgd:YNL210W(identity)	-	-	crc64:D23EC9B4849D73BA	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:VNi9aUeavD8+CCi+n1DXS+7mmbs9606	rogid:z5sxL8DmpJlmKWc7u/shEOoJkrQ559292	intact-crc:4ADDE375F0F07481|rigid:41Yb9vz0z9pMOt+GLAV4Yrjvdx4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P15873	uniprotkb:P63279	intact:EBI-12993|uniprotkb:D6VQ89|ensemblfungi:YBR088C	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	psi-mi:pcna_yeast(display_long)|uniprotkb:YBR0811(orf name)|uniprotkb:YBR088C(locus name)|uniprotkb:POL30(gene name)|psi-mi:POL30(display_short)	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11538939|imex:IM-24995-1742	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009645.1|sgd:S000000292|go:"GO:0043626"(PCNA complex)|go:"GO:0070987"(error-free translesion synthesis)|go:"GO:1902394"(positive regulation of exodeoxyribonuclease activity)|go:"GO:1903022"(positive regulation of phosphodiesterase activity, acting on 3'-phosphoglycolate-terminated DNA strands)|go:"GO:1905779"(positive regulation of exonuclease activity)|interpro:IPR000730(Proliferating cell nuclear antigen, PCNA)|interpro:IPR022648|interpro:IPR022649|interpro:IPR022659|rcsb pdb:1PLQ|rcsb pdb:1PLR|rcsb pdb:1SXJ|rcsb pdb:2OD8|rcsb pdb:3F1W|rcsb pdb:3GPM|rcsb pdb:3GPN|rcsb pdb:3L0W|rcsb pdb:4L6P|rcsb pdb:3L0X|rcsb pdb:3L10|rcsb pdb:4YHR|rcsb pdb:3PGE|rcsb pdb:3V60|rcsb pdb:3V61|rcsb pdb:3V62|rcsb pdb:5JNE|rcsb pdb:4L60|mint:P15873|dip:DIP-2417N|go:"GO:0035753"(maintenance of DNA trinucleotide repeats)|ensemblfungi:YBR088C(gene)|ensemblfungi:YBR088C_mRNA(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000710"(meiotic mismatch repair)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005657"(replication fork)|go:"GO:0006272"(leading strand elongation)|go:"GO:0006273"(lagging strand elongation)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006298"(mismatch repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0006348"|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0019985"(translesion synthesis)|go:"GO:0030337"(DNA polymerase processivity factor activity)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0034087"(establishment of mitotic sister chromatid cohesion)|go:"GO:0042802"(identical protein binding)|rcsb pdb:5T9D|rcsb pdb:5V7K|rcsb pdb:5V7M|rcsb pdb:5ZUT|rcsb pdb:6CX2|rcsb pdb:6CX3|rcsb pdb:6CX4|rcsb pdb:6D0Q|rcsb pdb:6D0R|rcsb pdb:6E49|rcsb pdb:6W9W|rcsb pdb:6WAC|reactome:R-SCE-110312|reactome:R-SCE-110320|reactome:R-SCE-4615885|reactome:R-SCE-5358565|reactome:R-SCE-5655862|reactome:R-SCE-5656121|reactome:R-SCE-5656169|reactome:R-SCE-6782135|reactome:R-SCE-69091|reactome:R-SCE-69166|reactome:R-SCE-69183|reactome:R-SCE-8866654|rcsb pdb:5V7L|sgd:YBR088C(identity)	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N|entrezgene/locuslink:7329(identity)	-	crc64:9B56C5851621DDDC	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:/+XSPV99OBBwBBC/nY0JiHaAeSI559292	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	intact-crc:8F71F10884B0D221|rigid:YdniTwKdzx3mimAIA3uHlEvBwf0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q08379	uniprotkb:P17157	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	intact:EBI-13327|uniprotkb:Q03089|uniprotkb:Q06888|ensemblfungi:YPL031C|uniprotkb:D6W3Y2	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:pho85_yeast(display_long)|uniprotkb:PHO85(gene name)|psi-mi:PHO85(display_short)|uniprotkb:SSG3(gene name synonym)|uniprotkb:P7102.18A(orf name)|uniprotkb:Serine/threonine-protein kinase PHO85(gene name synonym)|uniprotkb:Negative regulator of the PHO system(gene name synonym)|uniprotkb:YPL031C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11538966|imex:IM-24995-1745	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N|entrezgene/locuslink:2801(identity)	refseq:NP_015294.1|sgd:S000005952|ensemblfungi:YPL031C(gene)|ensemblfungi:YPL031C_mRNA(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016242"(negative regulation of macroautophagy)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032878"(regulation of establishment or maintenance of cell polarity)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045719"(negative regulation of glycogen biosynthetic process)|go:"GO:0045936"(negative regulation of phosphate metabolic process)|go:"GO:0046822"(regulation of nucleocytoplasmic transport)|go:"GO:0050849"(negative regulation of calcium-mediated signaling)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0005737"(cytoplasm)|rcsb pdb:2PK9|rcsb pdb:2PMI|rcsb pdb:4KRC|rcsb pdb:4KRD|go:"GO:0005634"(nucleus)|go:"GO:0071073"(positive regulation of phospholipid biosynthetic process)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901987"(regulation of cell cycle phase transition)|go:"GO:1990860"(Pho85-Pho80 CDK-cyclin complex)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P17157|dip:DIP-1493N|sgd:YPL031C(identity)	-	-	crc64:246A4358870B00EC	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2017/05/26	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	rogid:hrRlpgrzGGTT3/GQ5x0LgsjaGeE559292	intact-crc:E90BCC632A23A8E0|rigid:yhUw4ej2ECe4hzP0ttntGIKK+bM	false	sufficient binding region:383-1002	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O96006	uniprotkb:P17157	intact:EBI-740037|uniprotkb:Q96BY4|ensembl:ENSP00000370616|ensembl:ENSP00000370620|ensembl:ENSP00000370621|ensembl:ENSP00000498725	intact:EBI-13327|uniprotkb:Q03089|uniprotkb:Q06888|ensemblfungi:YPL031C|uniprotkb:D6W3Y2	psi-mi:zbed1_human(display_long)|uniprotkb:ZBED1(gene name)|psi-mi:ZBED1(display_short)|uniprotkb:ALTE(gene name synonym)|uniprotkb:DREF(gene name synonym)|uniprotkb:KIAA0785(gene name synonym)|uniprotkb:TRAMP(gene name synonym)|uniprotkb:dREF homolog(gene name synonym)|uniprotkb:Putative Ac-like transposable element(gene name synonym)|uniprotkb:DNA replication-related element-binding factor(gene name synonym)|uniprotkb:Zinc finger BED domain-containing protein 1(gene name synonym)|uniprotkb:hDREF(gene name synonym)	psi-mi:pho85_yeast(display_long)|uniprotkb:PHO85(gene name)|psi-mi:PHO85(display_short)|uniprotkb:SSG3(gene name synonym)|uniprotkb:P7102.18A(orf name)|uniprotkb:Serine/threonine-protein kinase PHO85(gene name synonym)|uniprotkb:Negative regulator of the PHO system(gene name synonym)|uniprotkb:YPL031C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11538977|imex:IM-24995-1746	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164606.1|refseq:NP_001164607.1|refseq:NP_004720.1|ensembl:ENSG00000214717(gene)|ensembl:ENST00000381218(transcript)|ensembl:ENST00000381222(transcript)|ensembl:ENST00000381223(transcript)|ensembl:ENST00000652001(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0031965"(nuclear membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044828"(negative regulation by host of viral genome replication)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0061665"(SUMO ligase activity)|go:"GO:1990466"(protein autosumoylation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003656(Zinc finger, BED-type predicted)|interpro:IPR008906(HAT dimerisation)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR036236|mint:O96006|rcsb pdb:2CT5|reactome:R-HSA-4551638|go:"GO:0005813"(centrosome)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016605"(PML body)|entrezgene/locuslink:9189(identity)	refseq:NP_015294.1|sgd:S000005952|ensemblfungi:YPL031C(gene)|ensemblfungi:YPL031C_mRNA(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016242"(negative regulation of macroautophagy)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032878"(regulation of establishment or maintenance of cell polarity)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045719"(negative regulation of glycogen biosynthetic process)|go:"GO:0045936"(negative regulation of phosphate metabolic process)|go:"GO:0046822"(regulation of nucleocytoplasmic transport)|go:"GO:0050849"(negative regulation of calcium-mediated signaling)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0005737"(cytoplasm)|rcsb pdb:2PK9|rcsb pdb:2PMI|rcsb pdb:4KRC|rcsb pdb:4KRD|go:"GO:0005634"(nucleus)|go:"GO:0071073"(positive regulation of phospholipid biosynthetic process)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901987"(regulation of cell cycle phase transition)|go:"GO:1990860"(Pho85-Pho80 CDK-cyclin complex)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P17157|dip:DIP-1493N|sgd:YPL031C(identity)	-	-	crc64:246A4358870B00EC	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:jl97ZV2Kz5YAmQKktWt/wk7OkRw9606	rogid:hrRlpgrzGGTT3/GQ5x0LgsjaGeE559292	intact-crc:08CD2C270E20899A|rigid:bv1kpjcMnZ71+67yBuT1w6rQrXM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P17214	intact:EBI-11523568	intact:EBI-6684|uniprotkb:Q05997|uniprotkb:D6VYN3|ensemblfungi:YLR233C	-	psi-mi:est1_yeast(display_long)|uniprotkb:EST1(gene name)|psi-mi:EST1(display_short)|uniprotkb:YLR233C(locus name)|uniprotkb:L8083.15(orf name)|uniprotkb:Ever shorter telomeres protein 1(gene name synonym)	psi-mi:nav2(display_short)|psi-mi:EBI-11523568(display_long)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11538995|imex:IM-24995-1748	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013334.1|sgd:S000004223|reactome:R-SCE-975957|dip:DIP-1306N|ensemblfungi:YLR233C(gene)|ensemblfungi:YLR233C_mRNA(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005730"(nucleolus)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0032210"(regulation of telomere maintenance via telomerase)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0071919"(G-quadruplex DNA formation)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR018834|interpro:IPR019458|sgd:YLR233C(identity)	entrezgene/locuslink:89797(identity)	-	crc64:9CF552AFDA6BDEDE	no-uniprot-update:	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:hu3SMHhlU1yKF9bVHdYQucREmxQ559292	rogid:WyH5VrQlZ4x7Sr5Hd4ApJ74qrL49606	intact-crc:292D4288AB11155A|rigid:J1SSoGLyVpnh58nSouQ0nL7cFuk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9NSC5	uniprotkb:P17157	intact:EBI-748420|uniprotkb:O14580|uniprotkb:O95350|uniprotkb:Q9NSB9|uniprotkb:Q9NSC0|intact:EBI-2557809|uniprotkb:E9PCW9|uniprotkb:Q9NSC1|intact:EBI-28972925|ensembl:ENSP00000376162|ensembl:ENSP00000439937|ensembl:ENSP00000446026|intact:EBI-10175777|uniprotkb:B2RA10	intact:EBI-13327|uniprotkb:Q03089|uniprotkb:Q06888|ensemblfungi:YPL031C|uniprotkb:D6W3Y2	psi-mi:home3_human(display_long)|uniprotkb:HOMER3(gene name)|psi-mi:HOMER3(display_short)	psi-mi:pho85_yeast(display_long)|uniprotkb:PHO85(gene name)|psi-mi:PHO85(display_short)|uniprotkb:SSG3(gene name synonym)|uniprotkb:P7102.18A(orf name)|uniprotkb:Serine/threonine-protein kinase PHO85(gene name synonym)|uniprotkb:Negative regulator of the PHO system(gene name synonym)|uniprotkb:YPL031C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11538986|imex:IM-24995-1747	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000221222|ensembl:ENSP00000221222|ensembl:ENSP00000376162|ensembl:ENST00000433218|ensembl:ENSP00000396154|ensembl:ENSP00000439937|ensembl:ENSP00000446026|ensembl:ENST00000594439|ensembl:ENSP00000471835|refseq:XP_006723006.1|refseq:XP_006723007.1|refseq:NP_001139193.1|refseq:NP_001139194.1|refseq:NP_004829.3|refseq:NP_001139196.1|ensembl:ENSG00000051128(gene)|ensembl:ENST00000392351(transcript)|ensembl:ENST00000539827(transcript)|ensembl:ENST00000542541(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006605"(protein targeting)|go:"GO:0007216"(G protein-coupled glutamate receptor signaling pathway)|go:"GO:0014069"(postsynaptic density)|go:"GO:0030425"(dendrite)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0035256"(G protein-coupled glutamate receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|go:"GO:2001256"(regulation of store-operated calcium entry)|interpro:IPR000697(EVH1)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR044100|mint:Q9NSC5|rcsb pdb:2P8V|rcsb pdb:3CVF|reactome:R-HSA-6794361|entrezgene/locuslink:9454(identity)	refseq:NP_015294.1|sgd:S000005952|ensemblfungi:YPL031C(gene)|ensemblfungi:YPL031C_mRNA(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016242"(negative regulation of macroautophagy)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032878"(regulation of establishment or maintenance of cell polarity)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045719"(negative regulation of glycogen biosynthetic process)|go:"GO:0045936"(negative regulation of phosphate metabolic process)|go:"GO:0046822"(regulation of nucleocytoplasmic transport)|go:"GO:0050849"(negative regulation of calcium-mediated signaling)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0005737"(cytoplasm)|rcsb pdb:2PK9|rcsb pdb:2PMI|rcsb pdb:4KRC|rcsb pdb:4KRD|go:"GO:0005634"(nucleus)|go:"GO:0071073"(positive regulation of phospholipid biosynthetic process)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901987"(regulation of cell cycle phase transition)|go:"GO:1990860"(Pho85-Pho80 CDK-cyclin complex)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P17157|dip:DIP-1493N|sgd:YPL031C(identity)	-	-	crc64:246A4358870B00EC	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:U1y/y52nnf7zQUCNQlqk7JDgXi49606	rogid:hrRlpgrzGGTT3/GQ5x0LgsjaGeE559292	intact-crc:7223C3DBA1C39579|rigid:t1O3hmM+iD7DreqbG4upHbUR+uI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P17695	uniprotkb:Q96EQ0	intact:EBI-7699|uniprotkb:Q6B234|uniprotkb:D6VTD4|ensemblfungi:YDR513W	intact:EBI-744081|ensembl:ENSP00000370395	psi-mi:glrx2_yeast(display_long)|uniprotkb:TTR(gene name synonym)|uniprotkb:GRX2(gene name)|psi-mi:GRX2(display_short)|uniprotkb:Thioltransferase(gene name synonym)|uniprotkb:Glutathione-dependent oxidoreductase 2(gene name synonym)|uniprotkb:TTR1(gene name synonym)|uniprotkb:D9719.17(orf name)|uniprotkb:YDR513W(locus name)	psi-mi:sgtb_human(display_long)|uniprotkb:Beta-SGT(gene name synonym)|uniprotkb:Small glutamine-rich protein with tetratricopeptide repeats 2(gene name synonym)|uniprotkb:SGTB(gene name)|psi-mi:SGTB(display_short)|uniprotkb:SGT2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11539040|imex:IM-24995-1753	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010801.1|sgd:S000002921|dip:DIP-5271N|ensemblfungi:YDR513W(gene)|ensemblfungi:YDR513W_mRNA(transcript)|go:"GO:0004362"("glutathione-disulfide reductase (NADPH) activity")|go:"GO:0004364"(glutathione transferase activity)|go:"GO:0004602"(glutathione peroxidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0015036"(disulfide oxidoreductase activity)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0097573"(glutathione oxidoreductase activity)|interpro:IPR002109(Glutaredoxin)|interpro:IPR011767(Glutaredoxin active site)|interpro:IPR011899(Glutaredoxin, eukaryotic and viruses)|interpro:IPR014025(Glutaredoxin subgroup)|interpro:IPR036249|rcsb pdb:3CTF|rcsb pdb:3CTG|rcsb pdb:3D4M|rcsb pdb:3D5J|sgd:YDR513W(identity)	refseq:NP_061945.1|refseq:XP_005248605.1|ensembl:ENSG00000197860(gene)|ensembl:ENST00000381007(transcript)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0072380"(TRC complex)|go:"GO:1903646"(positive regulation of chaperone-mediated protein folding)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR032374|entrezgene/locuslink:54557(identity)	-	crc64:99A79B87695B2266	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:u4CcRMaG3tJhhzqf3yNKktvKfv4559292	rogid:emIgH8U/yVmXT00Ty9yybIqQqas9606	intact-crc:4222B06C5D12123A|rigid:UOpuro/yb07aRANWDzKKbv6TiI8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P17695	uniprotkb:O43765	intact:EBI-7699|uniprotkb:Q6B234|uniprotkb:D6VTD4|ensemblfungi:YDR513W	intact:EBI-347996|ensembl:ENSP00000221566|ensembl:ENSP00000503397|ensembl:ENSP00000504495|uniprotkb:Q9BTZ9|intact:EBI-1045243|uniprotkb:Q6FIA9|uniprotkb:D6W610	psi-mi:glrx2_yeast(display_long)|uniprotkb:TTR(gene name synonym)|uniprotkb:GRX2(gene name)|psi-mi:GRX2(display_short)|uniprotkb:Thioltransferase(gene name synonym)|uniprotkb:Glutathione-dependent oxidoreductase 2(gene name synonym)|uniprotkb:TTR1(gene name synonym)|uniprotkb:D9719.17(orf name)|uniprotkb:YDR513W(locus name)	psi-mi:sgta_human(display_long)|uniprotkb:SGTA(gene name)|psi-mi:SGTA(display_short)|uniprotkb:SGT(gene name synonym)|uniprotkb:Alpha-SGT(gene name synonym)|uniprotkb:Vpu-binding protein(gene name synonym)|uniprotkb:SGT1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11539031|imex:IM-24995-1752	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010801.1|sgd:S000002921|dip:DIP-5271N|ensemblfungi:YDR513W(gene)|ensemblfungi:YDR513W_mRNA(transcript)|go:"GO:0004362"("glutathione-disulfide reductase (NADPH) activity")|go:"GO:0004364"(glutathione transferase activity)|go:"GO:0004602"(glutathione peroxidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0015036"(disulfide oxidoreductase activity)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0097573"(glutathione oxidoreductase activity)|interpro:IPR002109(Glutaredoxin)|interpro:IPR011767(Glutaredoxin active site)|interpro:IPR011899(Glutaredoxin, eukaryotic and viruses)|interpro:IPR014025(Glutaredoxin subgroup)|interpro:IPR036249|rcsb pdb:3CTF|rcsb pdb:3CTG|rcsb pdb:3D4M|rcsb pdb:3D5J|sgd:YDR513W(identity)	rcsb pdb:4CPG|rcsb pdb:4GOD|rcsb pdb:4GOE|rcsb pdb:4GOF|reactome:R-HSA-9609523|rcsb pdb:2VYI|ensembl:ENSG00000104969(gene)|ensembl:ENST00000221566(transcript)|ensembl:ENST00000676943(transcript)|ensembl:ENST00000677149(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072380"(TRC complex)|go:"GO:0098850"(extrinsic component of synaptic vesicle membrane)|go:"GO:1903070"(negative regulation of ER-associated ubiquitin-dependent protein catabolic process)|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)|go:"GO:1903646"(positive regulation of chaperone-mediated protein folding)|go:"GO:1904288"(BAT3 complex binding)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR032374|mint:O43765|refseq:XP_011526480.1|refseq:NP_003012.1|entrezgene/locuslink:6449(identity)	-	crc64:99A79B87695B2266	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:u4CcRMaG3tJhhzqf3yNKktvKfv4559292	rogid:r/Cyj4UJk/cS8QdrbjhTZMPCigI9606	intact-crc:ED11B46950AC92E7|rigid:UrLJNS0V1U9lTAQcdJO0Z/NX+X0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P17423	uniprotkb:P63279	intact:EBI-9685|ensemblfungi:YHR025W|uniprotkb:D3DKX2	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	psi-mi:khse_yeast(display_long)|uniprotkb:THR1(gene name)|psi-mi:THR1(display_short)|uniprotkb:YHR025W(locus name)	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11539022|imex:IM-24995-1751	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YHR025W(gene)|ensemblfungi:YHR025W_mRNA(transcript)|go:"GO:0004413"(homoserine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0009088"(threonine biosynthetic process)|go:"GO:0009092"(homoserine metabolic process)|interpro:IPR000870(Homoserine kinase)|interpro:IPR006203(GHMP kinase, ATP-binding, conserved site)|interpro:IPR006204(GHMP kinase)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR020568|interpro:IPR036554|refseq:NP_011890.1|sgd:S000001067|dip:DIP-4305N|mint:P17423|sgd:YHR025W(identity)	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N|entrezgene/locuslink:7329(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:S6tiEUJn7YZY4ydBnYraAdecCRY559292	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	intact-crc:F2E30D14D3F0733E|rigid:KOg4s/9QXLC+PzaNW9zzYbldD3A	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P17255	uniprotkb:P43355	intact:EBI-20245|uniprotkb:O74301|uniprotkb:Q9Y7W5|uniprotkb:D6VRG7|ensemblfungi:YDL185W	intact:EBI-740978|ensembl:ENSP00000349085|uniprotkb:O00346|uniprotkb:B2RC81	psi-mi:vata_yeast(display_long)|uniprotkb:VMA1(gene name)|psi-mi:VMA1(display_short)|uniprotkb:CLS8(gene name synonym)|uniprotkb:TFP1(gene name synonym)|uniprotkb:YDL185W(locus name)|uniprotkb:D1286(orf name)|uniprotkb:Vacuolar proton pump subunit A(gene name synonym)	psi-mi:maga1_human(display_long)|uniprotkb:MAGE-1 antigen(gene name synonym)|uniprotkb:Antigen MZ2-E(gene name synonym)|uniprotkb:Cancer/testis antigen 1.1(gene name synonym)|uniprotkb:MAGEA1(gene name)|psi-mi:MAGEA1(display_short)|uniprotkb:MAGE1(gene name synonym)|uniprotkb:MAGE1A(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11539013|imex:IM-24995-1750	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010096.1|sgd:S000002344|mint:P17255|ensemblfungi:YDL185W(gene)|ensemblfungi:YDL185W_mRNA(transcript)|go:"GO:0000221"(vacuolar proton-transporting V-type ATPase, V1 domain)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0003677"(DNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006314"(intron homing)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0012505"(endomembrane system)|go:"GO:0016539"(intein-mediated protein splicing)|go:"GO:0044267"(cellular protein metabolic process)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR003586(Hedgehog/intein hint domain, C-terminal)|interpro:IPR003587(Hedgehog/intein hint, N-terminal)|interpro:IPR004042(Intein DOD homing endonuclease)|interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR006141(Intein splicing site)|interpro:IPR006142(Intein)|interpro:IPR007868(Hom-end-associated Hint)|interpro:IPR007869(Homing endonuclease)|interpro:IPR020003|interpro:IPR022878|interpro:IPR023366|interpro:IPR027417|interpro:IPR027434|interpro:IPR030934|interpro:IPR031686|interpro:IPR036121|interpro:IPR036844|rcsb pdb:1DFA|rcsb pdb:1EF0|rcsb pdb:1GPP|rcsb pdb:1JVA|rcsb pdb:1LWS|rcsb pdb:1LWT|rcsb pdb:1UM2|rcsb pdb:1VDE|rcsb pdb:3J9T|rcsb pdb:3J9U|rcsb pdb:3J9V|rcsb pdb:5BW9|rcsb pdb:5D80|rcsb pdb:5VOX|rcsb pdb:5VOY|rcsb pdb:5VOZ|reactome:R-SCE-1222556|reactome:R-SCE-77387|reactome:R-SCE-917977|reactome:R-SCE-9639288|interpro:IPR024034|dip:DIP-2293N|sgd:YDL185W(identity)	refseq:NP_004979.3|ensembl:ENSG00000198681(gene)|ensembl:ENST00000356661(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|interpro:IPR002190(MAGE protein)|interpro:IPR021072|interpro:IPR030093|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|rcsb pdb:1W72|rcsb pdb:3BO8|dip:DIP-54794N|entrezgene/locuslink:4100(identity)	-	crc64:2A4C65D2F59426FD	crc64:544EEB1F9F4E9D33	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:YdmGZxIMX2IXMHC4EO85uOAf1Hg559292	rogid:6XW3mnTNM3yvOtXmiFbU8Uz3hjA9606	intact-crc:836E5D11307D5172|rigid:eU2IYpxCFkXgEheF4T+xo6dsyI0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P17214	uniprotkb:O14641	intact:EBI-6684|uniprotkb:Q05997|uniprotkb:D6VYN3|ensemblfungi:YLR233C	intact:EBI-740850|ensembl:ENSP00000005340|uniprotkb:Q53XM0|uniprotkb:D3DTN3	psi-mi:est1_yeast(display_long)|uniprotkb:EST1(gene name)|psi-mi:EST1(display_short)|uniprotkb:YLR233C(locus name)|uniprotkb:L8083.15(orf name)|uniprotkb:Ever shorter telomeres protein 1(gene name synonym)	psi-mi:dvl2_human(display_long)|uniprotkb:DSH homolog 2(gene name synonym)|uniprotkb:DVL2(gene name)|psi-mi:DVL2(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11539004|imex:IM-24995-1749	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013334.1|sgd:S000004223|reactome:R-SCE-975957|dip:DIP-1306N|ensemblfungi:YLR233C(gene)|ensemblfungi:YLR233C_mRNA(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005730"(nucleolus)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0032210"(regulation of telomere maintenance via telomerase)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0071919"(G-quadruplex DNA formation)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR018834|interpro:IPR019458|sgd:YLR233C(identity)	refseq:NP_004413.1|ensembl:ENSG00000004975(gene)|ensembl:ENST00000005340(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005109"(frizzled binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0007507"(heart development)|go:"GO:0016235"(aggresome)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044340"(canonical Wnt signaling pathway involved in regulation of cell proliferation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0150012"(positive regulation of neuron projection arborization)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008341(Dishevelled-2 region)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:O14641|rcsb pdb:2REY|rcsb pdb:3CBX|rcsb pdb:3CBY|rcsb pdb:3CBZ|rcsb pdb:3CC0|rcsb pdb:4WIP|rcsb pdb:5LNP|rcsb pdb:5SUY|rcsb pdb:5SUZ|rcsb pdb:6IW3|rcsb pdb:6JCK|reactome:R-HSA-201681|reactome:R-HSA-201688|reactome:R-HSA-2028269|reactome:R-HSA-4086400|reactome:R-HSA-4608870|reactome:R-HSA-4641258|reactome:R-HSA-4641262|reactome:R-HSA-5099900|reactome:R-HSA-5368598|reactome:R-HSA-5663220|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9673324|ensembl:ENSP00000005340|dip:DIP-34433N|entrezgene/locuslink:1856(identity)	-	crc64:9CF552AFDA6BDEDE	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:hu3SMHhlU1yKF9bVHdYQucREmxQ559292	rogid:2Vdc8oRnT4Mz/j+EXQXrL3AszOc9606	intact-crc:13D6413AA77B112E|rigid:mkiA782rXN9MsNLHSrz90WSvBRE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8N5R6	uniprotkb:P18961	intact:EBI-740841|intact:EBI-953781|uniprotkb:B3KQ49|uniprotkb:A8K3U4|uniprotkb:A8MPQ6|uniprotkb:A8MV61|uniprotkb:A8MVU9|uniprotkb:Q9H5Q6|uniprotkb:Q8TAX6|intact:EBI-2320546|intact:EBI-11522976	intact:EBI-29484|uniprotkb:D6VZS6|ensemblfungi:YMR104C	psi-mi:ccd33_human(display_long)|uniprotkb:CCDC33(gene name)|psi-mi:CCDC33(display_short)|uniprotkb:Cancer/testis antigen 61(gene name synonym)	psi-mi:ypk2_yeast(display_long)|uniprotkb:YPK2(gene name)|psi-mi:YPK2(display_short)|uniprotkb:YKR2(gene name synonym)|uniprotkb:YMR104C(locus name)|uniprotkb:YM9718.03C(orf name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11539076|imex:IM-24995-1757	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_079331.3|interpro:IPR000008(C2 calcium-dependent membrane targeting)|go:"GO:0005777"(peroxisome)|refseq:NP_001274110.1|refseq:NP_877592.2|mint:Q8N5R6|interpro:IPR035892|interpro:IPR039889|entrezgene/locuslink:80125(identity)	refseq:NP_013822.1|sgd:S000004710|dip:DIP-4438N|mint:P18961|ensemblfungi:YMR104C(gene)|ensemblfungi:YMR104C_mRNA(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0060237"(regulation of fungal-type cell wall organization)|go:"GO:0070941"(eisosome assembly)|go:"GO:0071555"(cell wall organization)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|sgd:YMR104C(identity)	-	-	crc64:E1FAB0295386A113	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2021/11/30	rogid:eEIn7pQyfdHWx8TeLJpYy0i/gww9606	rogid:wDHCJlSmOMy9MWExwxHzLA4+dO0559292	intact-crc:93656B42FE60554F|rigid:G9G1d64MxZogkpe+g+zrI4doMs4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P18496	uniprotkb:Q6RW13-2	intact:EBI-3323|uniprotkb:Q06020|uniprotkb:D6VZ28|ensemblfungi:YLR393W	intact:EBI-11522760|ensembl:ENSP00000365816	psi-mi:atp10_yeast(display_long)|uniprotkb:ATP10(gene name)|psi-mi:ATP10(display_short)|uniprotkb:L8084.8(orf name)|uniprotkb:YLR393W(locus name)	psi-mi:q6rw13-2(display_long)|uniprotkb:AGTRAP(gene name)|psi-mi:AGTRAP(display_short)|uniprotkb:AT1 receptor-associated protein(gene name synonym)|uniprotkb:ATRAP(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11539067|imex:IM-24995-1756	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013497.1|sgd:S000004385|dip:DIP-4641N|ensemblfungi:YLR393W(gene)|ensemblfungi:YLR393W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0032592"(integral component of mitochondrial membrane)|go:"GO:0033615"(mitochondrial proton-transporting ATP synthase complex assembly)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR007849(ATP10)|sgd:YLR393W(identity)	ensembl:ENSG00000177674(gene)|ensembl:ENST00000376629(transcript)|intact:EBI-741181(isoform-parent)|uniprotkb:Q6RW13-2(isoform-parent)|entrezgene/locuslink:57085(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:3LfbKFFgOegWNYA+M/jOd0ORiAk559292	rogid:PNzVis/8puQZBJ562gCqZKc078s9606	intact-crc:5D42A02030A67C40|rigid:RjK1ml/F9cQO92ApAhPt9NTHlcc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9Y6N9-4	uniprotkb:P17967	intact:EBI-11523636|ensembl:ENSP00000436934	intact:EBI-13012|uniprotkb:D6VQX3|ensemblfungi:YCL043C	psi-mi:q9y6n9-4(display_long)|uniprotkb:USH1C(gene name)|psi-mi:USH1C(display_short)|uniprotkb:AIE75(gene name synonym)|uniprotkb:Antigen NY-CO-38/NY-CO-37(gene name synonym)|uniprotkb:Autoimmune enteropathy-related antigen AIE-75(gene name synonym)|uniprotkb:Protein PDZ-73(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-3(gene name synonym)|uniprotkb:Usher syndrome type-1C protein(gene name synonym)	psi-mi:pdi_yeast(display_long)|uniprotkb:TRG1(gene name synonym)|uniprotkb:YCL313(orf name)|uniprotkb:PDI1(gene name)|psi-mi:PDI1(display_short)|uniprotkb:MFP1(gene name synonym)|uniprotkb:Thioredoxin-related glycoprotein 1(gene name synonym)|uniprotkb:YCL43C(orf name)|uniprotkb:YCL043C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11539058|imex:IM-24995-1755	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000006611(gene)|ensembl:ENST00000527020(transcript)|intact:EBI-954308(isoform-parent)|uniprotkb:Q9Y6N9-4(isoform-parent)|entrezgene/locuslink:10083(identity)	refseq:NP_009887.1|sgd:S000000548|mint:P17967|dip:DIP-4978N|ensemblfungi:YCL043C(gene)|ensemblfungi:YCL043C_mRNA(transcript)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006457"(protein folding)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0036508"(protein alpha-1,2-demannosylation)|go:"GO:0051082"(unfolded protein binding)|go:"GO:1904382"(mannose trimming involved in glycoprotein ERAD pathway)|interpro:IPR005792(Protein disulphide isomerase)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017937|interpro:IPR036249|rcsb pdb:2B5E|rcsb pdb:3BOA|reactome:R-SCE-901042|sgd:YCL043C(identity)	-	isoform-comment:No experimental confirmation available.	crc64:69CF3E05D7F74C94	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:lC4fbXfsFOZFtutcdQYHSWpgcJY9606	rogid:tyy52cf76yr9hl+9ggGGS4zDO/A559292	intact-crc:DE3AAE842F1A9F19|rigid:O5OTQq4ev081rwavpiPaYwg+7MA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P17709	uniprotkb:Q14145	intact:EBI-8744|ensemblfungi:YCL040W|uniprotkb:D6VQX5	intact:EBI-751001|uniprotkb:B3KPD5|uniprotkb:Q8WTX1|uniprotkb:Q6LEP0|uniprotkb:Q9BPY9|intact:EBI-28976014|ensembl:ENSP00000171111|ensembl:ENSP00000377245	psi-mi:hxkg_yeast(display_long)|uniprotkb:GLK1(gene name)|psi-mi:GLK1(display_short)|uniprotkb:HOR3(gene name synonym)|uniprotkb:YCL040W(locus name)|uniprotkb:YCL40W(orf name)|uniprotkb:YCL312(orf name)|uniprotkb:Glucose kinase 1(gene name synonym)	psi-mi:keap1_human(display_long)|uniprotkb:Cytosolic inhibitor of Nrf2(gene name synonym)|uniprotkb:Kelch-like protein 19(gene name synonym)|uniprotkb:KEAP1(gene name)|psi-mi:KEAP1(display_short)|uniprotkb:INRF2(gene name synonym)|uniprotkb:KIAA0132(gene name synonym)|uniprotkb:KLHL19(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11539049|imex:IM-24995-1754	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:6PDT|reactome:R-SCE-170822|reactome:R-SCE-6798695|reactome:R-SCE-70171|go:"GO:0005536"(glucose binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006013"(mannose metabolic process)|go:"GO:0006096"(glycolytic process)|go:"GO:0008865"(fructokinase activity)|go:"GO:0019158"(mannokinase activity)|go:"GO:0046323"(glucose import)|go:"GO:0051156"(glucose 6-phosphate metabolic process)|interpro:IPR001312(Hexokinase)|interpro:IPR019807|interpro:IPR022672|interpro:IPR022673|interpro:IPR043129|rcsb pdb:6P4X|ensemblfungi:YCL040W(gene)|ensemblfungi:YCL040W_mRNA(transcript)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0004340"(glucokinase activity)|go:"GO:0005524"(ATP binding)|refseq:NP_009890.1|sgd:S000000545|mint:P17709|dip:DIP-525N|sgd:YCL040W(identity)	refseq:NP_036421.2|refseq:NP_987096.1|ensembl:ENSP00000171111|ensembl:ENSP00000377245|refseq:XP_011526754.1|refseq:XP_005260230.1|refseq:XP_005260231.1|dip:DIP-42134N|ensembl:ENSG00000079999(gene)|ensembl:ENST00000171111(transcript)|ensembl:ENST00000393623(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0016234"(inclusion body)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030496"(midbody)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0034451"(centriolar satellite)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045604"(regulation of epidermal cell differentiation)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR017096(Kelch-like protein, gigaxonin)|interpro:IPR030563|mint:Q14145|rcsb pdb:1U6D|rcsb pdb:1ZGK|rcsb pdb:2FLU|rcsb pdb:3VNG|rcsb pdb:3VNH|rcsb pdb:3ZGC|rcsb pdb:3ZGD|rcsb pdb:4CXI|rcsb pdb:4CXJ|rcsb pdb:4CXT|rcsb pdb:4IFJ|rcsb pdb:4IFL|rcsb pdb:4IFN|rcsb pdb:4IN4|rcsb pdb:4IQK|rcsb pdb:4L7B|rcsb pdb:4L7C|rcsb pdb:4L7D|rcsb pdb:4N1B|rcsb pdb:4XMB|rcsb pdb:5DAD|rcsb pdb:5DAF|rcsb pdb:5F72|rcsb pdb:5GIT|rcsb pdb:5NLB|rcsb pdb:5WFL|rcsb pdb:5WFV|rcsb pdb:5WG1|rcsb pdb:5WHL|rcsb pdb:5WHO|rcsb pdb:5WIY|rcsb pdb:5X54|rcsb pdb:6FFM|rcsb pdb:6FMP|rcsb pdb:6FMQ|rcsb pdb:6HWS|rcsb pdb:6LRZ|rcsb pdb:6ROG|rcsb pdb:6SP1|rcsb pdb:6SP4|rcsb pdb:6T7V|rcsb pdb:6T7Z|rcsb pdb:6TG8|rcsb pdb:6TYM|rcsb pdb:6TYP|rcsb pdb:6UF0|rcsb pdb:6W66|rcsb pdb:6W67|rcsb pdb:6W68|rcsb pdb:6W69|rcsb pdb:6WCQ|rcsb pdb:6Z6A|rcsb pdb:7K28|rcsb pdb:7K29|rcsb pdb:7K2A|rcsb pdb:7K2B|rcsb pdb:7K2C|rcsb pdb:7K2D|rcsb pdb:7K2E|rcsb pdb:7K2F|rcsb pdb:7K2G|rcsb pdb:7K2H|rcsb pdb:7K2I|rcsb pdb:7K2J|rcsb pdb:7K2K|rcsb pdb:7K2L|rcsb pdb:7K2M|rcsb pdb:7K2N|rcsb pdb:7K2O|rcsb pdb:7K2P|rcsb pdb:7K2Q|rcsb pdb:7K2R|rcsb pdb:7K2S|reactome:R-HSA-5689880|reactome:R-HSA-8932339|reactome:R-HSA-8951664|reactome:R-HSA-983168|rcsb pdb:6V6Z|entrezgene/locuslink:9817(identity)	-	crc64:A7A417041D7A961F	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:r6qkUttc6MTLWY6RYa26ZBCw2zg559292	rogid:3y/KqnUK+5nIyjhOEfkkthmP1OA9606	intact-crc:4247F7486427DC78|rigid:YG4NPEf1kZrlg9Su05LxmqNqT0s	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P19955	uniprotkb:Q13643	intact:EBI-16295|ensemblfungi:YFR049W|uniprotkb:D6VTT2	intact:EBI-741101|ensembl:ENSP00000362107|uniprotkb:Q6I9T0|uniprotkb:Q9BVA2|uniprotkb:D3DPT6	psi-mi:rt31_yeast(display_long)|uniprotkb:YFR049W(locus name)|uniprotkb:YMR31(gene name)|psi-mi:YMR31(display_short)	psi-mi:fhl3_human(display_long)|uniprotkb:FHL3(gene name)|psi-mi:FHL3(display_short)|uniprotkb:SLIM2(gene name synonym)|uniprotkb:Skeletal muscle LIM-protein 2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11539121|imex:IM-24995-1762	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000001945|ensemblfungi:YFR049W(gene)|ensemblfungi:YFR049W_mRNA(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005761"(mitochondrial ribosome)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006103"(2-oxoglutarate metabolic process)|interpro:IPR020373|go:"GO:0009353"(mitochondrial oxoglutarate dehydrogenase complex)|refseq:NP_116707.3|dip:DIP-5447N|mint:P19955|sgd:YFR049W(identity)	refseq:NP_004459.2|ensembl:ENSG00000183386(gene)|ensembl:ENST00000373016(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005925"(focal adhesion)|go:"GO:0007517"(muscle organ development)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0046872"(metal ion binding)|interpro:IPR001781(Zinc finger, LIM-type)|mint:Q13643|rcsb pdb:1WYH|rcsb pdb:2CUQ|rcsb pdb:2EHE|interpro:IPR037987|refseq:NP_001230807.1|dip:DIP-42030N|entrezgene/locuslink:2275(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:6QZyCc2+sOr3rdTswAxjMopU9/A559292	rogid:RAo+b/VgFSnHSbgR+zXuxJvypxM9606	intact-crc:0E1C6FE366F3D250|rigid:5dxyVPMtLsP9iRozP88z/4JGD64	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P31153	uniprotkb:P19358	intact:EBI-1050743|uniprotkb:Q53SP5|uniprotkb:A8K511|uniprotkb:D6W5L1|ensembl:ENSP00000303147|uniprotkb:B4DN45	intact:EBI-10795|uniprotkb:E9P927|ensemblfungi:YDR502C|uniprotkb:D6VTC4	psi-mi:metk2_human(display_long)|uniprotkb:Methionine adenosyltransferase 2(gene name synonym)|uniprotkb:Methionine adenosyltransferase II(gene name synonym)|uniprotkb:MAT2A(gene name)|psi-mi:MAT2A(display_short)|uniprotkb:AMS2(gene name synonym)|uniprotkb:MATA2(gene name synonym)	psi-mi:metk2_yeast(display_long)|uniprotkb:SAM2(gene name)|psi-mi:SAM2(display_short)|uniprotkb:ETH2(gene name synonym)|uniprotkb:YDR502C(locus name)|uniprotkb:D9719.8(orf name)|uniprotkb:Methionine adenosyltransferase 2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11539112|imex:IM-24995-1761	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005902.1|rcsb pdb:5A1G|rcsb pdb:5A1I|rcsb pdb:5UGH|rcsb pdb:6FAJ|rcsb pdb:6FBN|rcsb pdb:6FBO|rcsb pdb:6FBP|rcsb pdb:6FCB|rcsb pdb:6FCD|rcsb pdb:6FWB|ensembl:ENSG00000168906(gene)|ensembl:ENST00000306434(transcript)|go:"GO:0004478"(methionine adenosyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006556"(S-adenosylmethionine biosynthetic process)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0034214"(protein hexamerization)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048269"(methionine adenosyltransferase complex)|go:"GO:0051291"(protein heterooligomerization)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR002133(S-adenosylmethionine synthetase)|rcsb pdb:6G6R|rcsb pdb:6P9V|rcsb pdb:6WKB|interpro:IPR022628|rcsb pdb:7BHR|rcsb pdb:7BHS|interpro:IPR022629|interpro:IPR022630|interpro:IPR022631|interpro:IPR022636|mint:P31153|rcsb pdb:2P02|rcsb pdb:4KTT|rcsb pdb:4KTV|rcsb pdb:4NDN|rcsb pdb:5A19|rcsb pdb:7BHT|rcsb pdb:7BHU|rcsb pdb:7BHV|rcsb pdb:7BHW|rcsb pdb:7BHX|rcsb pdb:7KCC|rcsb pdb:7KCE|rcsb pdb:7KCF|rcsb pdb:7KDA|rcsb pdb:7KDB|rcsb pdb:7L1A|reactome:R-HSA-156581|entrezgene/locuslink:4144(identity)	ensemblfungi:YDR502C(gene)|ensemblfungi:YDR502C_mRNA(transcript)|go:"GO:0006556"(S-adenosylmethionine biosynthetic process)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0046872"(metal ion binding)|interpro:IPR002133(S-adenosylmethionine synthetase)|interpro:IPR022628|interpro:IPR022629|interpro:IPR022630|interpro:IPR022631|interpro:IPR022636|reactome:R-SCE-156581|reactome:R-SCE-1614635|reactome:R-SCE-2408508|go:"GO:0004478"(methionine adenosyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006555"(methionine metabolic process)|sgd:S000002910|refseq:NP_010790.3|mint:P19358|dip:DIP-4001N|sgd:YDR502C(identity)	-	-	crc64:0AFCB0BA386F088B	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:8QDKkbuHcvQtfzy2XkVjCKjTK709606	rogid:fLg9TMOk+nR4ZuRNqkqur0qzv/E559292	intact-crc:8F015E60A4ADB189|rigid:OAdSwEtKPQ2xBwonkNrjPt/ZKpY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UGJ1-2	uniprotkb:P18961	intact:EBI-10964469|ensembl:ENSP00000456648	intact:EBI-29484|uniprotkb:D6VZS6|ensemblfungi:YMR104C	psi-mi:q9ugj1-2(display_long)|uniprotkb:TUBGCP4(gene name)|psi-mi:TUBGCP4(display_short)|uniprotkb:76P(gene name synonym)|uniprotkb:GCP4(gene name synonym)|uniprotkb:Gamma-ring complex protein 76 kDa(gene name synonym)	psi-mi:ypk2_yeast(display_long)|uniprotkb:YPK2(gene name)|psi-mi:YPK2(display_short)|uniprotkb:YKR2(gene name synonym)|uniprotkb:YMR104C(locus name)|uniprotkb:YM9718.03C(orf name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11539103|imex:IM-24995-1760	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-1052544(isoform-parent)|ensembl:ENSG00000137822(gene)|ensembl:ENST00000564079(transcript)|uniprotkb:Q9UGJ1-2(isoform-parent)|entrezgene/locuslink:27229(identity)	refseq:NP_013822.1|sgd:S000004710|dip:DIP-4438N|mint:P18961|ensemblfungi:YMR104C(gene)|ensemblfungi:YMR104C_mRNA(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0060237"(regulation of fungal-type cell wall organization)|go:"GO:0070941"(eisosome assembly)|go:"GO:0071555"(cell wall organization)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|sgd:YMR104C(identity)	-	-	crc64:E1FAB0295386A113	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:+lfeIRS3N2OU1+y84kUyKY7ePNA9606	rogid:wDHCJlSmOMy9MWExwxHzLA4+dO0559292	intact-crc:4A10F501365079F3|rigid:ipJEgY3MjfpnuYhhjgXoypki4dk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P18961	uniprotkb:Q9BRK4	intact:EBI-29484|uniprotkb:D6VZS6|ensemblfungi:YMR104C	intact:EBI-741037|ensembl:ENSP00000359240|ensembl:ENSP00000359243|uniprotkb:Q8N3I0|uniprotkb:Q96J79|uniprotkb:Q96JL2|uniprotkb:B1AL14|uniprotkb:D3DR72	psi-mi:ypk2_yeast(display_long)|uniprotkb:YPK2(gene name)|psi-mi:YPK2(display_short)|uniprotkb:YKR2(gene name synonym)|uniprotkb:YMR104C(locus name)|uniprotkb:YM9718.03C(orf name)	psi-mi:lzts2_human(display_long)|uniprotkb:Protein LAPSER1(gene name synonym)|uniprotkb:LZTS2(gene name)|psi-mi:LZTS2(display_short)|uniprotkb:KIAA1813(gene name synonym)|uniprotkb:LAPSER1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11539094|imex:IM-24995-1759	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013822.1|sgd:S000004710|dip:DIP-4438N|mint:P18961|ensemblfungi:YMR104C(gene)|ensemblfungi:YMR104C_mRNA(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0060237"(regulation of fungal-type cell wall organization)|go:"GO:0070941"(eisosome assembly)|go:"GO:0071555"(cell wall organization)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|sgd:YMR104C(identity)	refseq:NP_115805.1|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030496"(midbody)|go:"GO:0031982"(vesicle)|go:"GO:0051013"(microtubule severing)|go:"GO:0051168"(nuclear export)|go:"GO:0051255"(spindle midzone assembly)|go:"GO:0060682"(primary ureteric bud growth)|go:"GO:0072197"(ureter morphogenesis)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|interpro:IPR028597|mint:Q9BRK4|ensembl:ENSG00000107816(gene)|ensembl:ENST00000370220(transcript)|ensembl:ENST00000370223(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0008285"(negative regulation of cell population proliferation)|refseq:XP_016872269.1|refseq:NP_001305028.1|refseq:NP_001305029.1|refseq:NP_001305030.1|refseq:XP_005270279.1|entrezgene/locuslink:84445(identity)	-	crc64:E1FAB0295386A113	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:wDHCJlSmOMy9MWExwxHzLA4+dO0559292	rogid:OaMJmnmfm6JniKUJeyg7fS6zRcw9606	intact-crc:7C6DBF8BD49DB27F|rigid:jd2ap/wQphjhYJ/mLe0t8IsF0HU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P18961	uniprotkb:O00444	intact:EBI-29484|uniprotkb:D6VZS6|ensemblfungi:YMR104C	intact:EBI-746202|uniprotkb:Q8IYF0|uniprotkb:Q96Q95|uniprotkb:B2RAL0|uniprotkb:B7Z837|uniprotkb:B7Z8G7|uniprotkb:Q9UD84|uniprotkb:Q9UDE2|ensembl:ENSP00000270861	psi-mi:ypk2_yeast(display_long)|uniprotkb:YPK2(gene name)|psi-mi:YPK2(display_short)|uniprotkb:YKR2(gene name synonym)|uniprotkb:YMR104C(locus name)|uniprotkb:YM9718.03C(orf name)	psi-mi:plk4_human(display_long)|uniprotkb:Polo-like kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase Sak(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 18(gene name synonym)|uniprotkb:PLK4(gene name)|psi-mi:PLK4(display_short)|uniprotkb:SAK(gene name synonym)|uniprotkb:STK18(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11539085|imex:IM-24995-1758	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013822.1|sgd:S000004710|dip:DIP-4438N|mint:P18961|ensemblfungi:YMR104C(gene)|ensemblfungi:YMR104C_mRNA(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0060237"(regulation of fungal-type cell wall organization)|go:"GO:0070941"(eisosome assembly)|go:"GO:0071555"(cell wall organization)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|sgd:YMR104C(identity)	refseq:NP_001177728.1|refseq:NP_001177730.1|refseq:NP_055079.3|dip:DIP-34467N|rcsb pdb:5LHZ|rcsb pdb:6N45|rcsb pdb:6N46|rcsb pdb:6W38|rcsb pdb:6W3I|rcsb pdb:6W3J|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|rcsb pdb:5LHY|reactome:R-HSA-5620912|reactome:R-HSA-8854518|ensembl:ENSG00000142731(gene)|ensembl:ENST00000270861(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0001741"(XY body)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007099"(centriole replication)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0046601"(positive regulation of centriole replication)|go:"GO:0060271"(cilium assembly)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0098535"(de novo centriole assembly involved in multi-ciliated epithelial cell differentiation)|go:"GO:0098536"(deuterosome)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033696|interpro:IPR033698|interpro:IPR033699|interpro:IPR033700|mint:O00444|rcsb pdb:2N19|rcsb pdb:3COK|rcsb pdb:4JXF|rcsb pdb:4N7V|rcsb pdb:4N7Z|rcsb pdb:4N9J|rcsb pdb:4YUR|rcsb pdb:4YYP|entrezgene/locuslink:10733(identity)	-	crc64:E1FAB0295386A113	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:wDHCJlSmOMy9MWExwxHzLA4+dO0559292	rogid:xqjVEnoGXDk/+2AzLRAkyPK80OI9606	intact-crc:05049E831AD83FA1|rigid:t8IsHTPshCST0iHthikEDRrlCys	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O43186	uniprotkb:P20053	intact:EBI-748171|uniprotkb:Q0QD45|ensembl:ENSP00000221996|ensembl:ENSP00000445565	intact:EBI-219|uniprotkb:D6W4H8|ensemblfungi:YPR178W	psi-mi:crx_human(display_long)|uniprotkb:CRX(gene name)|psi-mi:CRX(display_short)|uniprotkb:CORD2(gene name synonym)	psi-mi:prp4_yeast(display_long)|uniprotkb:PRP4(gene name)|psi-mi:PRP4(display_short)|uniprotkb:RNA4(gene name synonym)|uniprotkb:YPR178W(locus name)|uniprotkb:P9705.6(orf name)|uniprotkb:Pre-mRNA-processing protein 4(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11539157|imex:IM-24995-1766	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000545.1|ensembl:ENSG00000105392(gene)|ensembl:ENST00000221996(transcript)|ensembl:ENST00000539067(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007601"(visual perception)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050896"(response to stimulus)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013851(Transcription factor Otx, C-terminal)|interpro:IPR017970|entrezgene/locuslink:1406(identity)	refseq:NP_015504.1|sgd:S000006382|mint:P20053|dip:DIP-2607N|ensemblfungi:YPR178W(gene)|ensemblfungi:YPR178W_mRNA(transcript)|go:"GO:0000393"(spliceosomal conformational changes to generate catalytic conformation)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0030621"(U4 snRNA binding)|go:"GO:0034247"(snoRNA splicing)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR014906("Pre-mRNA processing factor 4 (PRP4) like")|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|rcsb pdb:3JCM|rcsb pdb:5GAN|rcsb pdb:5GAP|rcsb pdb:5NRL|rcsb pdb:5ZWM|rcsb pdb:5ZWO|sgd:YPR178W(identity)	-	-	crc64:7CCCA3A92AC0CE78	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:v/bkO/0iLzq1Q2HtieWQQ40RF9M9606	rogid:vvz5G0rqqyrugTvAPelDKit9FpQ559292	intact-crc:2C3FDEF65B0ACD00|rigid:5xdYT8xK3b48eAEKcfSQjFxSIxw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:A0A024R0Y4	uniprotkb:P20053	intact:EBI-11523730|ensembl:ENSP00000477709|ensembl:ENSP00000478363|ensembl:ENSP00000481091	intact:EBI-219|uniprotkb:D6W4H8|ensemblfungi:YPR178W	psi-mi:a0a024r0y4_human(display_long)|uniprotkb:TADA2A(gene name)|psi-mi:TADA2A(display_short)|uniprotkb:TADA2L(gene name synonym)|uniprotkb:hCG_28187(orf name)	psi-mi:prp4_yeast(display_long)|uniprotkb:PRP4(gene name)|psi-mi:PRP4(display_short)|uniprotkb:RNA4(gene name synonym)|uniprotkb:YPR178W(locus name)|uniprotkb:P9705.6(orf name)|uniprotkb:Pre-mRNA-processing protein 4(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11539148|imex:IM-24995-1765	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001159577.2|refseq:NP_001479.4|ensembl:ENSG00000276234(gene)|ensembl:ENST00000612272(transcript)|ensembl:ENST00000615182(transcript)|ensembl:ENST00000620628(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031063"(regulation of histone deacetylation)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0035065"(regulation of histone acetylation)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090043"(regulation of tubulin deacetylation)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016827(Transcriptional adaptor 2)|interpro:IPR017884|interpro:IPR017930|interpro:IPR036388|interpro:IPR041983|interpro:IPR043145|entrezgene/locuslink:6871(identity)	refseq:NP_015504.1|sgd:S000006382|mint:P20053|dip:DIP-2607N|ensemblfungi:YPR178W(gene)|ensemblfungi:YPR178W_mRNA(transcript)|go:"GO:0000393"(spliceosomal conformational changes to generate catalytic conformation)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0030621"(U4 snRNA binding)|go:"GO:0034247"(snoRNA splicing)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR014906("Pre-mRNA processing factor 4 (PRP4) like")|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|rcsb pdb:3JCM|rcsb pdb:5GAN|rcsb pdb:5GAP|rcsb pdb:5NRL|rcsb pdb:5ZWM|rcsb pdb:5ZWO|sgd:YPR178W(identity)	-	-	crc64:7CCCA3A92AC0CE78	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:IGh7vC68gMLe+tAVGM4gc0rzc6Y9606	rogid:vvz5G0rqqyrugTvAPelDKit9FpQ559292	intact-crc:06EAFA57D1EA2D49|rigid:OC6yQLt062fWuC2VxG3k80O5t54	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8N5R6	uniprotkb:P20053	intact:EBI-740841|intact:EBI-953781|uniprotkb:B3KQ49|uniprotkb:A8K3U4|uniprotkb:A8MPQ6|uniprotkb:A8MV61|uniprotkb:A8MVU9|uniprotkb:Q9H5Q6|uniprotkb:Q8TAX6|intact:EBI-2320546|intact:EBI-11522976	intact:EBI-219|uniprotkb:D6W4H8|ensemblfungi:YPR178W	psi-mi:ccd33_human(display_long)|uniprotkb:CCDC33(gene name)|psi-mi:CCDC33(display_short)|uniprotkb:Cancer/testis antigen 61(gene name synonym)	psi-mi:prp4_yeast(display_long)|uniprotkb:PRP4(gene name)|psi-mi:PRP4(display_short)|uniprotkb:RNA4(gene name synonym)|uniprotkb:YPR178W(locus name)|uniprotkb:P9705.6(orf name)|uniprotkb:Pre-mRNA-processing protein 4(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11539139|imex:IM-24995-1764	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_079331.3|interpro:IPR000008(C2 calcium-dependent membrane targeting)|go:"GO:0005777"(peroxisome)|refseq:NP_001274110.1|refseq:NP_877592.2|mint:Q8N5R6|interpro:IPR035892|interpro:IPR039889|entrezgene/locuslink:80125(identity)	refseq:NP_015504.1|sgd:S000006382|mint:P20053|dip:DIP-2607N|ensemblfungi:YPR178W(gene)|ensemblfungi:YPR178W_mRNA(transcript)|go:"GO:0000393"(spliceosomal conformational changes to generate catalytic conformation)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0030621"(U4 snRNA binding)|go:"GO:0034247"(snoRNA splicing)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR014906("Pre-mRNA processing factor 4 (PRP4) like")|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|rcsb pdb:3JCM|rcsb pdb:5GAN|rcsb pdb:5GAP|rcsb pdb:5NRL|rcsb pdb:5ZWM|rcsb pdb:5ZWO|sgd:YPR178W(identity)	-	-	crc64:7CCCA3A92AC0CE78	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2021/11/30	rogid:eEIn7pQyfdHWx8TeLJpYy0i/gww9606	rogid:vvz5G0rqqyrugTvAPelDKit9FpQ559292	intact-crc:6AB561E130CB6BFC|rigid:ptA+Hsnjl/Y0xmHa4k1KOheQruE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O75928-2	uniprotkb:P20049	intact:EBI-348567|ensembl:ENSP00000317163|intact:EBI-7259183|intact:MINT-1455402	intact:EBI-19686|uniprotkb:D6VQG2|ensemblfungi:YBR166C	psi-mi:o75928-2(display_long)|uniprotkb:Msx-interacting zinc finger protein(gene name synonym)|uniprotkb:PIAS-NY protein(gene name synonym)|uniprotkb:Protein inhibitor of activated STAT x(gene name synonym)|uniprotkb:Protein inhibitor of activated STAT2(gene name synonym)|uniprotkb:PIAS2(gene name)|psi-mi:PIAS2(display_short)|uniprotkb:PIASX(gene name synonym)|uniprotkb:Androgen receptor-interacting protein 3(gene name synonym)|uniprotkb:DAB2-interacting protein(gene name synonym)|uniprotkb:PIASx-alpha(isoform synonym)|uniprotkb:ARIP3(isoform synonym)|uniprotkb:E3 SUMO-protein transferase PIAS2(gene name synonym)	psi-mi:tyr1_yeast(display_long)|uniprotkb:TYR1(gene name)|psi-mi:TYR1(display_short)|uniprotkb:YBR1218(orf name)|uniprotkb:YBR166C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11539130|imex:IM-24995-1763	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-348555(pias2_human)|ensembl:ENSG00000078043(gene)|ensembl:ENST00000324794(transcript)|uniprotkb:O75928-2(isoform-parent)|entrezgene/locuslink:9063(identity)	refseq:NP_009725.1|sgd:S000000370|ensemblfungi:YBR166C(gene)|ensemblfungi:YBR166C_mRNA(transcript)|go:"GO:0004665"("prephenate dehydrogenase (NADP+) activity")|go:"GO:0005737"(cytoplasm)|go:"GO:0006570"(tyrosine metabolic process)|go:"GO:0006571"(tyrosine biosynthetic process)|go:"GO:0008652"(cellular amino acid biosynthetic process)|go:"GO:0008977"("prephenate dehydrogenase (NAD+) activity")|go:"GO:0070403"(NAD+ binding)|interpro:IPR003099(Prephenate dehydrogenase)|interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|interpro:IPR012385(Prephenate dehydrogenase, fungal)|interpro:IPR036291|dip:DIP-4627N|mint:P20049|sgd:YBR166C(identity)	-	isoform-comment:"Contains a glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) at position 562."	crc64:D483B93ABBC8F8F4	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:JNC3UGf8YuVcrXbFnO27d4orf4I9606	rogid:tqskEEcG2cewNJk/xHHqihVa8ss559292	intact-crc:D236E1905969F059|rigid:GzTNSfB4U5rOKiODhLM8nL6bcyY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P20053	uniprotkb:Q8NHQ1	intact:EBI-219|uniprotkb:D6W4H8|ensemblfungi:YPR178W	intact:EBI-739624|ensembl:ENSP00000264982|ensembl:ENSP00000419231|uniprotkb:Q96B31|uniprotkb:Q9H2C3|uniprotkb:Q9H2Z1|uniprotkb:Q9H940|uniprotkb:D3DNE9|uniprotkb:B7Z5I8|uniprotkb:B7Z7E8|uniprotkb:F5GZX8	psi-mi:prp4_yeast(display_long)|uniprotkb:PRP4(gene name)|psi-mi:PRP4(display_short)|uniprotkb:RNA4(gene name synonym)|uniprotkb:YPR178W(locus name)|uniprotkb:P9705.6(orf name)|uniprotkb:Pre-mRNA-processing protein 4(gene name synonym)	psi-mi:cep70_human(display_long)|uniprotkb:CEP70(gene name)|psi-mi:CEP70(display_short)|uniprotkb:BITE(gene name synonym)|uniprotkb:p10-binding protein(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11539195|imex:IM-24995-1770	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015504.1|sgd:S000006382|mint:P20053|dip:DIP-2607N|ensemblfungi:YPR178W(gene)|ensemblfungi:YPR178W_mRNA(transcript)|go:"GO:0000393"(spliceosomal conformational changes to generate catalytic conformation)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0030621"(U4 snRNA binding)|go:"GO:0034247"(snoRNA splicing)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR014906("Pre-mRNA processing factor 4 (PRP4) like")|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|rcsb pdb:3JCM|rcsb pdb:5GAN|rcsb pdb:5GAP|rcsb pdb:5NRL|rcsb pdb:5ZWM|rcsb pdb:5ZWO|sgd:YPR178W(identity)	ensembl:ENSG00000114107(gene)|ensembl:ENST00000264982(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|interpro:IPR019734|interpro:IPR037692|mint:Q8NHQ1|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|ensembl:ENST00000484888(transcript)|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_077817.2|refseq:XP_016862764.1|refseq:NP_001275893.1|refseq:NP_001275894.1|refseq:NP_001275895.1|refseq:NP_001275896.1|refseq:NP_001307527.1|refseq:NP_001307529.1|entrezgene/locuslink:80321(identity)	-	crc64:7CCCA3A92AC0CE78	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:vvz5G0rqqyrugTvAPelDKit9FpQ559292	rogid:S4yveQWcvdVtAUX65gqrJ5Dv0Mc9606	intact-crc:42B7859FA8ECBD87|rigid:bYutni7rDWOdZwLAyW9uUowQ90M	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P20053	uniprotkb:Q8N6Y0	intact:EBI-219|uniprotkb:D6W4H8|ensemblfungi:YPR178W	intact:EBI-739895|uniprotkb:Q8NBX7|uniprotkb:Q96KH3|uniprotkb:Q9BYI8|uniprotkb:A8K7L6|uniprotkb:B2RCR9|ensembl:ENSP00000252597	psi-mi:prp4_yeast(display_long)|uniprotkb:PRP4(gene name)|psi-mi:PRP4(display_short)|uniprotkb:RNA4(gene name synonym)|uniprotkb:YPR178W(locus name)|uniprotkb:P9705.6(orf name)|uniprotkb:Pre-mRNA-processing protein 4(gene name synonym)	psi-mi:usbp1_human(display_long)|uniprotkb:USHBP1(gene name)|psi-mi:USHBP1(display_short)|uniprotkb:MCC-2(gene name synonym)|uniprotkb:AIE-75-binding protein(gene name synonym)|uniprotkb:AIEBP(gene name synonym)|uniprotkb:MCC2(gene name synonym)|uniprotkb:Mutated in colon cancer protein 2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11539186|imex:IM-24995-1769	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015504.1|sgd:S000006382|mint:P20053|dip:DIP-2607N|ensemblfungi:YPR178W(gene)|ensemblfungi:YPR178W_mRNA(transcript)|go:"GO:0000393"(spliceosomal conformational changes to generate catalytic conformation)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0030621"(U4 snRNA binding)|go:"GO:0034247"(snoRNA splicing)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR014906("Pre-mRNA processing factor 4 (PRP4) like")|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|rcsb pdb:3JCM|rcsb pdb:5GAN|rcsb pdb:5GAP|rcsb pdb:5NRL|rcsb pdb:5ZWM|rcsb pdb:5ZWO|sgd:YPR178W(identity)	refseq:NP_001284632.1|refseq:NP_114147.2|refseq:NP_001308346.1|ensembl:ENSG00000130307(gene)|ensembl:ENST00000252597(transcript)|go:"GO:0030165"(PDZ domain binding)|interpro:IPR019536|interpro:IPR040171|entrezgene/locuslink:83878(identity)	-	crc64:7CCCA3A92AC0CE78	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:vvz5G0rqqyrugTvAPelDKit9FpQ559292	rogid:vY1qx73Ju/z7WDu6k1kd10ZDVRo9606	intact-crc:2546349519E4F6B2|rigid:oGHx2Y1m3J2Qzbyujb+NjaM4buI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8N684-3	uniprotkb:P20053	intact:EBI-11523759|ensembl:ENSP00000345412	intact:EBI-219|uniprotkb:D6W4H8|ensemblfungi:YPR178W	psi-mi:q8n684-3(display_long)|uniprotkb:Cleavage factor Im complex 59 kDa subunit(gene name synonym)|uniprotkb:CPSF7(gene name)|psi-mi:CPSF7(display_short)|uniprotkb:Cleavage and polyadenylation specificity factor 59 kDa subunit(gene name synonym)|uniprotkb:Pre-mRNA cleavage factor Im 59 kDa subunit(gene name synonym)	psi-mi:prp4_yeast(display_long)|uniprotkb:PRP4(gene name)|psi-mi:PRP4(display_short)|uniprotkb:RNA4(gene name synonym)|uniprotkb:YPR178W(locus name)|uniprotkb:P9705.6(orf name)|uniprotkb:Pre-mRNA-processing protein 4(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11539175|imex:IM-24995-1768	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-746909(isoform-parent)|ensembl:ENSG00000149532(gene)|ensembl:ENST00000340437(transcript)|uniprotkb:Q8N684-3(isoform-parent)|entrezgene/locuslink:79869(identity)	refseq:NP_015504.1|sgd:S000006382|mint:P20053|dip:DIP-2607N|ensemblfungi:YPR178W(gene)|ensemblfungi:YPR178W_mRNA(transcript)|go:"GO:0000393"(spliceosomal conformational changes to generate catalytic conformation)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0030621"(U4 snRNA binding)|go:"GO:0034247"(snoRNA splicing)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR014906("Pre-mRNA processing factor 4 (PRP4) like")|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|rcsb pdb:3JCM|rcsb pdb:5GAN|rcsb pdb:5GAP|rcsb pdb:5NRL|rcsb pdb:5ZWM|rcsb pdb:5ZWO|sgd:YPR178W(identity)	-	-	crc64:7CCCA3A92AC0CE78	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:hnk6o9HBKsdIRWKRuEdjdByVKxM9606	rogid:vvz5G0rqqyrugTvAPelDKit9FpQ559292	intact-crc:BFB4F0E7B4C2187A|rigid:5QtYmVwYNwdsIJirXMxzEGeQUeU	false	sufficient binding region:44-514	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P14373	uniprotkb:P20053	intact:EBI-719493|uniprotkb:A2BE15|uniprotkb:Q5RJA8|uniprotkb:Q5ST26|uniprotkb:Q6LA73|uniprotkb:Q6NXR9|uniprotkb:Q9BZY6|uniprotkb:Q9UJL3|ensembl:ENSP00000383555|ensembl:ENSP00000392787|ensembl:ENSP00000405229|ensembl:ENSP00000414793|ensembl:ENSP00000366404	intact:EBI-219|uniprotkb:D6W4H8|ensemblfungi:YPR178W	psi-mi:tri27_human(display_long)|uniprotkb:TRIM27(gene name)|psi-mi:TRIM27(display_short)|uniprotkb:RNF76(gene name synonym)|uniprotkb:RFP(gene name synonym)|uniprotkb:Ret finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 27(gene name synonym)|uniprotkb:RING finger protein 76(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM27(gene name synonym)	psi-mi:prp4_yeast(display_long)|uniprotkb:PRP4(gene name)|psi-mi:PRP4(display_short)|uniprotkb:RNA4(gene name synonym)|uniprotkb:YPR178W(locus name)|uniprotkb:P9705.6(orf name)|uniprotkb:Pre-mRNA-processing protein 4(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11539166|imex:IM-24995-1767	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006501.1|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0090281"(negative regulation of calcium ion import)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR020457|interpro:IPR035791|interpro:IPR043136|mint:P14373|reactome:R-HSA-3232142|reactome:R-HSA-9635465|reactome:R-HSA-8948751|ensembl:ENSG00000204713(gene)|ensembl:ENSG00000215641(gene)|ensembl:ENSG00000229006(gene)|ensembl:ENSG00000234495(gene)|ensembl:ENSG00000237071(gene)|ensembl:ENST00000377199(transcript)|ensembl:ENST00000400720(transcript)|ensembl:ENST00000431123(transcript)|ensembl:ENST00000435528(transcript)|ensembl:ENST00000437160(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001650"(fibrillar center)|go:"GO:0002820"(negative regulation of adaptive immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|entrezgene/locuslink:5987(identity)	refseq:NP_015504.1|sgd:S000006382|mint:P20053|dip:DIP-2607N|ensemblfungi:YPR178W(gene)|ensemblfungi:YPR178W_mRNA(transcript)|go:"GO:0000393"(spliceosomal conformational changes to generate catalytic conformation)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0030621"(U4 snRNA binding)|go:"GO:0034247"(snoRNA splicing)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR014906("Pre-mRNA processing factor 4 (PRP4) like")|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|rcsb pdb:3JCM|rcsb pdb:5GAN|rcsb pdb:5GAP|rcsb pdb:5NRL|rcsb pdb:5ZWM|rcsb pdb:5ZWO|sgd:YPR178W(identity)	-	-	crc64:7CCCA3A92AC0CE78	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:dsfH5OUghD8KSaTz1SFw9OYVTK49606	rogid:vvz5G0rqqyrugTvAPelDKit9FpQ559292	intact-crc:48D9BD92E36BC75E|rigid:POgDzDouQfkuac4iSySiCK+tyQ8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P20081	uniprotkb:P53992	intact:EBI-6961|uniprotkb:D6W147|ensemblfungi:YNL135C	intact:EBI-81134|uniprotkb:Q8WV25|ensembl:ENSP00000321845|ensembl:ENSP00000343405|uniprotkb:B4DZT4	psi-mi:fkbp_yeast(display_long)|uniprotkb:RBP1(gene name synonym)|uniprotkb:N1213(orf name)|uniprotkb:N1845(orf name)|uniprotkb:YNL135C(locus name)|uniprotkb:FPR1(gene name)|psi-mi:FPR1(display_short)|uniprotkb:FKB1(gene name synonym)|uniprotkb:Peptidyl-prolyl cis-trans isomerase(gene name synonym)|uniprotkb:Rapamycin-binding protein(gene name synonym)	psi-mi:sc24c_human(display_long)|uniprotkb:SEC24C(gene name)|psi-mi:SEC24C(display_short)|uniprotkb:KIAA0079(gene name synonym)|uniprotkb:SEC24-related protein C(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11539224|imex:IM-24995-1773	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014264.1|sgd:S000005079|dip:DIP-1263N|mint:P20081|ensemblfungi:YNL135C(gene)|ensemblfungi:YNL135C_mRNA(transcript)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005527"(macrolide binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006325"(chromatin organization)|go:"GO:0006457"(protein folding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:1901710"(regulation of homoserine biosynthetic process)|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)|rcsb pdb:1YAT|sgd:YNL135C(identity)	go:"GO:0090110"(COPII-coated vesicle cargo loading)|go:"GO:0070971"(endoplasmic reticulum exit site)|interpro:IPR006895(Zinc finger, Sec23/Sec24-type)|interpro:IPR006896(Sec23/Sec24 trunk region)|interpro:IPR006900(Sec23/Sec24 helical region)|interpro:IPR007123(Gelsolin region)|interpro:IPR012990(Sec23/Sec24 beta-sandwich)|interpro:IPR029006|interpro:IPR036174|interpro:IPR036175|interpro:IPR036180|interpro:IPR036465|interpro:IPR041742|mint:P53992|rcsb pdb:3EH2|rcsb pdb:6PU1|reactome:R-HSA-1655829|reactome:R-HSA-204005|reactome:R-HSA-2132295|reactome:R-HSA-983170|reactome:R-HSA-5694530|ensembl:ENSG00000176986(gene)|ensembl:ENST00000339365(transcript)|ensembl:ENST00000345254(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0008270"(zinc ion binding)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0030127"(COPII vesicle coat)|refseq:NP_004913.2|refseq:NP_940999.1|dip:DIP-30981N|entrezgene/locuslink:9632(identity)	-	crc64:65C134830D300C06	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:8afvGSk+mPghtqkVoWd2rHJXXhQ559292	rogid:kOKJkIWFOlIpRFLj5JshAGqAg6s9606	intact-crc:619955A3F921C2CC|rigid:Zf31zF/KLpq8P12LqD+1kWSQAIY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P20081	uniprotkb:A0A0C4DGF1	intact:EBI-6961|uniprotkb:D6W147|ensemblfungi:YNL135C	intact:EBI-10188476|ensembl:ENSP00000433657	psi-mi:fkbp_yeast(display_long)|uniprotkb:RBP1(gene name synonym)|uniprotkb:N1213(orf name)|uniprotkb:N1845(orf name)|uniprotkb:YNL135C(locus name)|uniprotkb:FPR1(gene name)|psi-mi:FPR1(display_short)|uniprotkb:FKB1(gene name synonym)|uniprotkb:Peptidyl-prolyl cis-trans isomerase(gene name synonym)|uniprotkb:Rapamycin-binding protein(gene name synonym)	psi-mi:a0a0c4dgf1_human(display_long)|uniprotkb:ZBTB32(gene name)|psi-mi:ZBTB32(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11539215|imex:IM-24995-1772	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014264.1|sgd:S000005079|dip:DIP-1263N|mint:P20081|ensemblfungi:YNL135C(gene)|ensemblfungi:YNL135C_mRNA(transcript)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005527"(macrolide binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006325"(chromatin organization)|go:"GO:0006457"(protein folding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:1901710"(regulation of homoserine biosynthetic process)|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)|rcsb pdb:1YAT|sgd:YNL135C(identity)	interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|ensembl:ENSG00000011590(gene)|ensembl:ENST00000481182(transcript)|go:"GO:0042802"(identical protein binding)|entrezgene/locuslink:27033(identity)	-	crc64:65C134830D300C06	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:8afvGSk+mPghtqkVoWd2rHJXXhQ559292	rogid:w3k7YT4kw/T+Xi5YBqGHSpHtwMM9606	intact-crc:6F0148CBC62FC3CA|rigid:aH70cUocyuJplPpMqCt6QIeja2w	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UJV3-2	uniprotkb:P20053	intact:EBI-10172526|ensembl:ENSP00000413976	intact:EBI-219|uniprotkb:D6W4H8|ensemblfungi:YPR178W	psi-mi:q9ujv3-2(display_long)|uniprotkb:RING-type E3 ubiquitin transferase MID2(gene name synonym)|uniprotkb:FXY2(gene name synonym)|uniprotkb:Midin-2(gene name synonym)|uniprotkb:Midline defect 2(gene name synonym)|uniprotkb:Midline-2(gene name synonym)|uniprotkb:RING finger protein 60(gene name synonym)|uniprotkb:RNF60(gene name synonym)|uniprotkb:TRIM1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 1(gene name synonym)|uniprotkb:MID2(gene name)|psi-mi:MID2(display_short)	psi-mi:prp4_yeast(display_long)|uniprotkb:PRP4(gene name)|psi-mi:PRP4(display_short)|uniprotkb:RNA4(gene name synonym)|uniprotkb:YPR178W(locus name)|uniprotkb:P9705.6(orf name)|uniprotkb:Pre-mRNA-processing protein 4(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11539204|imex:IM-24995-1771	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-751983(isoform-parent)|uniprotkb:Q9UJV3-2(isoform-parent)|ensembl:ENSG00000080561(gene)|ensembl:ENST00000443968(transcript)|entrezgene/locuslink:11043(identity)	refseq:NP_015504.1|sgd:S000006382|mint:P20053|dip:DIP-2607N|ensemblfungi:YPR178W(gene)|ensemblfungi:YPR178W_mRNA(transcript)|go:"GO:0000393"(spliceosomal conformational changes to generate catalytic conformation)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0030621"(U4 snRNA binding)|go:"GO:0034247"(snoRNA splicing)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR014906("Pre-mRNA processing factor 4 (PRP4) like")|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|rcsb pdb:3JCM|rcsb pdb:5GAN|rcsb pdb:5GAP|rcsb pdb:5NRL|rcsb pdb:5ZWM|rcsb pdb:5ZWO|sgd:YPR178W(identity)	-	-	crc64:7CCCA3A92AC0CE78	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:/FJ+V2H7SaWon7caUWkEkmHFVxQ9606	rogid:vvz5G0rqqyrugTvAPelDKit9FpQ559292	intact-crc:604793E746BE5907|rigid:Y29ymQkU+f+NbtmdHZNAvPot/9U	false	sufficient binding region:21-705	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P20081	uniprotkb:Q16630-3	intact:EBI-6961|uniprotkb:D6W147|ensemblfungi:YNL135C	intact:EBI-11523850	psi-mi:fkbp_yeast(display_long)|uniprotkb:RBP1(gene name synonym)|uniprotkb:N1213(orf name)|uniprotkb:N1845(orf name)|uniprotkb:YNL135C(locus name)|uniprotkb:FPR1(gene name)|psi-mi:FPR1(display_short)|uniprotkb:FKB1(gene name synonym)|uniprotkb:Peptidyl-prolyl cis-trans isomerase(gene name synonym)|uniprotkb:Rapamycin-binding protein(gene name synonym)	psi-mi:q16630-3(display_long)|uniprotkb:CFIM68(gene name synonym)|uniprotkb:Cleavage and polyadenylation specificity factor 68 kDa subunit(gene name synonym)|uniprotkb:Pre-mRNA cleavage factor Im 68 kDa subunit(gene name synonym)|uniprotkb:Protein HPBRII-4/7(gene name synonym)|uniprotkb:CPSF6(gene name)|psi-mi:CPSF6(display_short)|uniprotkb:Cleavage factor Im complex 68 kDa subunit(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11539260|imex:IM-24995-1777	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014264.1|sgd:S000005079|dip:DIP-1263N|mint:P20081|ensemblfungi:YNL135C(gene)|ensemblfungi:YNL135C_mRNA(transcript)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005527"(macrolide binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006325"(chromatin organization)|go:"GO:0006457"(protein folding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:1901710"(regulation of homoserine biosynthetic process)|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)|rcsb pdb:1YAT|sgd:YNL135C(identity)	intact:EBI-358410(isoform-parent)|entrezgene/locuslink:11052(identity)	-	crc64:65C134830D300C06	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:8afvGSk+mPghtqkVoWd2rHJXXhQ559292	rogid:diwzHQNNZ4fMHYzs292gLpdKfE09606	intact-crc:59CA7579DF6FEAF4|rigid:MYZyptYN7WodpKxm8QFAfiQIfvE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P20081	uniprotkb:Q16630-2	intact:EBI-6961|uniprotkb:D6W147|ensemblfungi:YNL135C	intact:EBI-11088043|ensembl:ENSP00000266679	psi-mi:fkbp_yeast(display_long)|uniprotkb:RBP1(gene name synonym)|uniprotkb:N1213(orf name)|uniprotkb:N1845(orf name)|uniprotkb:YNL135C(locus name)|uniprotkb:FPR1(gene name)|psi-mi:FPR1(display_short)|uniprotkb:FKB1(gene name synonym)|uniprotkb:Peptidyl-prolyl cis-trans isomerase(gene name synonym)|uniprotkb:Rapamycin-binding protein(gene name synonym)	psi-mi:q16630-2(display_long)|uniprotkb:CPSF6(gene name)|psi-mi:CPSF6(display_short)|uniprotkb:CFIM68(gene name synonym)|uniprotkb:Cleavage and polyadenylation specificity factor 68 kDa subunit(gene name synonym)|uniprotkb:Pre-mRNA cleavage factor Im 68 kDa subunit(gene name synonym)|uniprotkb:Protein HPBRII-4/7(gene name synonym)|uniprotkb:Cleavage factor Im complex 68 kDa subunit(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11539251|imex:IM-24995-1776	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014264.1|sgd:S000005079|dip:DIP-1263N|mint:P20081|ensemblfungi:YNL135C(gene)|ensemblfungi:YNL135C_mRNA(transcript)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005527"(macrolide binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006325"(chromatin organization)|go:"GO:0006457"(protein folding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:1901710"(regulation of homoserine biosynthetic process)|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)|rcsb pdb:1YAT|sgd:YNL135C(identity)	intact:EBI-358410(isoform-parent)|ensembl:ENSG00000111605(gene)|ensembl:ENST00000266679(transcript)|uniprotkb:Q16630-2(isoform-parent)|entrezgene/locuslink:11052(identity)	-	crc64:65C134830D300C06	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:8afvGSk+mPghtqkVoWd2rHJXXhQ559292	rogid:y66l9ctsSYs6fhxdYD5CJ0cDZFA9606	intact-crc:C66AB578E53BE584|rigid:tJHZJQq9S7vVqWv1C+ntEmixQd8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P20081	uniprotkb:Q15427	intact:EBI-6961|uniprotkb:D6W147|ensemblfungi:YNL135C	intact:EBI-348469|ensembl:ENSP00000271628|intact:EBI-1047735|uniprotkb:Q5SZ63	psi-mi:fkbp_yeast(display_long)|uniprotkb:RBP1(gene name synonym)|uniprotkb:N1213(orf name)|uniprotkb:N1845(orf name)|uniprotkb:YNL135C(locus name)|uniprotkb:FPR1(gene name)|psi-mi:FPR1(display_short)|uniprotkb:FKB1(gene name synonym)|uniprotkb:Peptidyl-prolyl cis-trans isomerase(gene name synonym)|uniprotkb:Rapamycin-binding protein(gene name synonym)	psi-mi:sf3b4_human(display_long)|uniprotkb:SF3B4(gene name)|psi-mi:SF3B4(display_short)|uniprotkb:SAP49(gene name synonym)|uniprotkb:Spliceosome-associated protein 49(gene name synonym)|uniprotkb:Pre-mRNA-splicing factor SF3b 49 kDa subunit(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11539242|imex:IM-24995-1775	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014264.1|sgd:S000005079|dip:DIP-1263N|mint:P20081|ensemblfungi:YNL135C(gene)|ensemblfungi:YNL135C_mRNA(transcript)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005527"(macrolide binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006325"(chromatin organization)|go:"GO:0006457"(protein folding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:1901710"(regulation of homoserine biosynthetic process)|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)|rcsb pdb:1YAT|sgd:YNL135C(identity)	refseq:NP_005841.1|ensembl:ENSG00000143368(gene)|ensembl:ENST00000271628(transcript)|rcsb pdb:6QX9|rcsb pdb:6Y53|rcsb pdb:6Y5Q|rcsb pdb:7ABG|rcsb pdb:7ABH|rcsb pdb:7ABI|rcsb pdb:7DVQ|reactome:R-HSA-72163|reactome:R-HSA-72165|rcsb pdb:6AHD|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:1990935"(splicing factor binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034158|go:"GO:0000375"(RNA splicing, via transesterification reactions)|interpro:IPR034159|interpro:IPR035979|mint:Q15427|rcsb pdb:1X5T|rcsb pdb:5GVQ|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|entrezgene/locuslink:10262(identity)	-	crc64:65C134830D300C06	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:8afvGSk+mPghtqkVoWd2rHJXXhQ559292	rogid:Jgy6WmBFKkphpZLLte2GgsagUVI9606	intact-crc:A972E1B2E4BB9102|rigid:225teJT55udQNVL3ZYsd/JkGmp0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P81877	uniprotkb:P20081	intact:EBI-748077|uniprotkb:Q8N2Q2|uniprotkb:Q9BWW6|uniprotkb:Q9Y4T7|uniprotkb:B7Z2L9|uniprotkb:E9PDA8|uniprotkb:B2R5W1|uniprotkb:B7Z1J2|uniprotkb:B7Z665|uniprotkb:D6RH18|uniprotkb:E9PB74|intact:EBI-28967061|ensembl:ENSP00000322977	intact:EBI-6961|uniprotkb:D6W147|ensemblfungi:YNL135C	psi-mi:ssbp2_human(display_long)|uniprotkb:Sequence-specific single-stranded-DNA-binding protein 2(gene name synonym)|uniprotkb:SSBP2(gene name)|psi-mi:SSBP2(display_short)|uniprotkb:SSDP2(gene name synonym)	psi-mi:fkbp_yeast(display_long)|uniprotkb:RBP1(gene name synonym)|uniprotkb:N1213(orf name)|uniprotkb:N1845(orf name)|uniprotkb:YNL135C(locus name)|uniprotkb:FPR1(gene name)|psi-mi:FPR1(display_short)|uniprotkb:FKB1(gene name synonym)|uniprotkb:Peptidyl-prolyl cis-trans isomerase(gene name synonym)|uniprotkb:Rapamycin-binding protein(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11539233|imex:IM-24995-1774	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000322977|ensembl:ENST00000505980|ensembl:ENSP00000423969|ensembl:ENST00000509053|ensembl:ENSP00000422961|ensembl:ENST00000514493|ensembl:ENSP00000426183|ensembl:ENST00000515395|ensembl:ENSP00000424657|refseq:NP_001243661.1|refseq:NP_036578.2|refseq:NP_001243665.1|refseq:NP_001243663.1|refseq:NP_001243664.1|refseq:NP_001243662.1|ensembl:ENSG00000145687(gene)|ensembl:ENST00000320672(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR008116(Sequence-specific single-strand DNA-binding protein)|mint:P81877|rcsb pdb:6IWV|rcsb pdb:6TYD|dip:DIP-29459N|entrezgene/locuslink:23635(identity)	refseq:NP_014264.1|sgd:S000005079|dip:DIP-1263N|mint:P20081|ensemblfungi:YNL135C(gene)|ensemblfungi:YNL135C_mRNA(transcript)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005527"(macrolide binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006325"(chromatin organization)|go:"GO:0006457"(protein folding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:1901710"(regulation of homoserine biosynthetic process)|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)|rcsb pdb:1YAT|sgd:YNL135C(identity)	-	-	crc64:65C134830D300C06	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:CMmZPTurp1G6Y2q7GP/pTMlFM549606	rogid:8afvGSk+mPghtqkVoWd2rHJXXhQ559292	intact-crc:AAC97F6964E5D0E6|rigid:uZJRlMh9x8XnKjRL2xHC18tthvk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P20133	uniprotkb:Q15008	intact:EBI-3559|uniprotkb:P32433|uniprotkb:D6W4H7|ensemblfungi:YPR176C	intact:EBI-359701|uniprotkb:E9PHI9|uniprotkb:A8K2E0|ensembl:ENSP00000295901|uniprotkb:Q6UV22	psi-mi:pgtb2_yeast(display_long)|uniprotkb:Geranylgeranyl transferase type II subunit beta(gene name synonym)|uniprotkb:Type II protein geranyl-geranyltransferase subunit beta(gene name synonym)|uniprotkb:YPT1/SEC4 proteins geranylgeranyltransferase subunit beta(gene name synonym)|uniprotkb:BET2(gene name)|psi-mi:BET2(display_short)|uniprotkb:YPR176C(locus name)|uniprotkb:P9705.12(orf name)	psi-mi:psmd6_human(display_long)|uniprotkb:PSMD6(gene name)|psi-mi:PSMD6(display_short)|uniprotkb:KIAA0107(gene name synonym)|uniprotkb:PFAAP4(gene name synonym)|uniprotkb:26S proteasome regulatory subunit S10(gene name synonym)|uniprotkb:p42A(gene name synonym)|uniprotkb:Proteasome regulatory particle subunit p44S10(gene name synonym)|uniprotkb:Phosphonoformate immuno-associated protein 4(gene name synonym)|uniprotkb:Breast cancer-associated protein SGA-113M(gene name synonym)|uniprotkb:26S proteasome regulatory subunit RPN7(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11539307|imex:IM-24995-1782	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015502.1|sgd:S000006380|reactome:R-SCE-6803205|reactome:R-SCE-8873719|dip:DIP-2214N|ensemblfungi:YPR176C(gene)|ensemblfungi:YPR176C_mRNA(transcript)|go:"GO:0004663"(Rab geranylgeranyltransferase activity)|go:"GO:0005829"(cytosol)|go:"GO:0005968"(Rab-protein geranylgeranyltransferase complex)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0008270"(zinc ion binding)|go:"GO:0018342"(protein prenylation)|go:"GO:0018344"(protein geranylgeranylation)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001330(Prenyltransferase/squalene oxidase)|interpro:IPR008930(Terpenoid cylases/protein prenyltransferase alpha-alpha toroid)|interpro:IPR026873|sgd:YPR176C(identity)	refseq:NP_055629.1|ensembl:ENSG00000163636(gene)|ensembl:ENST00000295901(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019585|interpro:IPR035268|interpro:IPR036390|mint:Q15008|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4K|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSG|rcsb pdb:6MSH|reactome:R-HSA-5358346|reactome:R-HSA-1236978|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-1236974|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-69601|reactome:R-HSA-69481|refseq:NP_001258708.1|refseq:NP_001258709.1|refseq:NP_001258710.1|dip:DIP-27590N|entrezgene/locuslink:9861(identity)	-	crc64:6A9C44DFBE62AAFC	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Fxribu0N2yK6IA2GZDfO0YmqLAo559292	rogid:ULOM02v6J56vZLlAGn7wN3N6Efw9606	intact-crc:AADFF2774411B294|rigid:fL/QqaO2d11ZBD1qWxfd5l+y8o8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
intact:EBI-11523890	uniprotkb:P20107	-	intact:EBI-29667|uniprotkb:D6W070|ensemblfungi:YMR243C	psi-mi:a0a087wwc3_human(display_short)|psi-mi:EBI-11523890(display_long)|uniprotkb:PDCL2(gene name)|psi-mi:PDCL2(display_short)	psi-mi:zrc1_yeast(display_long)|uniprotkb:ZRC1(gene name)|psi-mi:ZRC1(display_short)|uniprotkb:YM9408.05C(orf name)|uniprotkb:YMR243C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11539298|imex:IM-24995-1781	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:A0A087WWC3(uniprot-removed-ac)|entrezgene/locuslink:132954(identity)	refseq:NP_013970.1|sgd:S000004856|dip:DIP-2030N|mint:P20107|ensemblfungi:YMR243C(gene)|ensemblfungi:YMR243C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005385"(zinc ion transmembrane transporter activity)|go:"GO:0006882"(cellular zinc ion homeostasis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0071577"(zinc ion transmembrane transport)|interpro:IPR002524(Cation efflux protein)|interpro:IPR027469|interpro:IPR036837|reactome:R-SCE-425410|reactome:R-SCE-435368|sgd:YMR243C(identity)	-	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:vhktqKnu+qJ9+neTG7Pkfxd3rG49606	rogid:ZZlCJ2Xj5Hiumdl3BNStZFS9qM4559292	intact-crc:11B1D0EFFC1E2918|rigid:TdKuORqOHMmkfsvl18iHcBjb19M	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q5D1E8	uniprotkb:P20095	intact:EBI-747793|uniprotkb:Q6I9Z1|uniprotkb:Q9H5P1|uniprotkb:D3DPT0|ensembl:ENSP00000362179	intact:EBI-13820|ensemblfungi:YNR011C|uniprotkb:D6W1I6	psi-mi:zc12a_human(display_long)|uniprotkb:MCPIP(gene name synonym)|uniprotkb:MCPIP1(gene name synonym)|uniprotkb:ZC3H12A(gene name)|psi-mi:ZC3H12A(display_short)|uniprotkb:Monocyte chemotactic protein-induced protein 1(gene name synonym)|uniprotkb:Regnase-1(gene name synonym)|uniprotkb:Zinc finger CCCH domain-containing protein 12A(gene name synonym)	psi-mi:prp2_yeast(display_long)|uniprotkb:PRP2(gene name)|psi-mi:PRP2(display_short)|uniprotkb:RNA2(gene name synonym)|uniprotkb:YNR011C(locus name)|uniprotkb:N2048(orf name)|uniprotkb:Pre-mRNA-processing protein 2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11539289|imex:IM-24995-1780	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_079355.2|refseq:NP_001310479.1|ensembl:ENSG00000163874(gene)|ensembl:ENST00000373087(transcript)|go:"GO:0000294"(nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay)|go:"GO:0000932"(P-body)|go:"GO:0001525"(angiogenesis)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0002757"(immune response-activating signal transduction)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0004532"(exoribonuclease activity)|go:"GO:0004540"(ribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007399"(nervous system development)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010656"(negative regulation of muscle cell apoptotic process)|go:"GO:0010884"(positive regulation of lipid storage)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0030154"(cell differentiation)|go:"GO:0030867"(rough endoplasmic reticulum membrane)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032691"(negative regulation of interleukin-1 beta production)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035198"(miRNA binding)|go:"GO:0035613"(RNA stem-loop binding)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042406"(extrinsic component of endoplasmic reticulum membrane)|go:"GO:0043022"(ribosome binding)|go:"GO:0043031"(negative regulation of macrophage activation)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0044828"(negative regulation by host of viral genome replication)|go:"GO:0045019"(negative regulation of nitric oxide biosynthetic process)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051607"(defense response to virus)|go:"GO:0055118"(negative regulation of cardiac muscle contraction)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0090501"(RNA phosphodiester bond hydrolysis)|go:"GO:0090502"(RNA phosphodiester bond hydrolysis, endonucleolytic)|go:"GO:0098586"(cellular response to virus)|go:"GO:1900016"(negative regulation of cytokine production involved in inflammatory response)|go:"GO:1900119"(positive regulation of execution phase of apoptosis)|go:"GO:1901223"(negative regulation of NIK/NF-kappaB signaling)|go:"GO:1903003"(positive regulation of protein deubiquitination)|go:"GO:1903799"(negative regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1903936"(cellular response to sodium arsenite)|go:"GO:1904637"(cellular response to ionomycin)|go:"GO:1990869"(cellular response to chemokine)|go:"GO:2000320"(negative regulation of T-helper 17 cell differentiation)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|go:"GO:2000627"(positive regulation of miRNA catabolic process)|interpro:IPR021869|interpro:IPR040546|interpro:IPR040757|rcsb pdb:3V32|rcsb pdb:3V33|rcsb pdb:3V34|go:"GO:1900745"(positive regulation of p38MAPK cascade)|entrezgene/locuslink:80149(identity)	refseq:NP_014408.1|sgd:S000005294|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|rcsb pdb:5GM6|rcsb pdb:5LQW|rcsb pdb:7DCO|rcsb pdb:7DCP|rcsb pdb:7DCQ|rcsb pdb:7DCR|rcsb pdb:7DD3|go:"GO:0140603"(obsolete ATP hydrolysis activity)|ensemblfungi:YNR011C(gene)|ensemblfungi:YNR011C_mRNA(transcript)|go:"GO:0000349"(generation of catalytic spliceosome for first transesterification step)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0008186"(ATP-dependent activity, acting on RNA)|go:"GO:0034247"(snoRNA splicing)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|mint:P20095|dip:DIP-3961N|sgd:YNR011C(identity)	-	-	crc64:7EB3E1EE93215F57	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:3FqqH/XrYjHaa5oJpPXvfYwHKCQ9606	rogid:wfkc/eidpcEF1HlVabj2p/arPiY559292	intact-crc:92F21118152C4163|rigid:1XVpLofLTzJg9RI/NFUp2L3C13M	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P20081	uniprotkb:Q9Y2W2	intact:EBI-6961|uniprotkb:D6W147|ensemblfungi:YNL135C	intact:EBI-714455|ensembl:ENSP00000261167|uniprotkb:Q96AY8	psi-mi:fkbp_yeast(display_long)|uniprotkb:RBP1(gene name synonym)|uniprotkb:N1213(orf name)|uniprotkb:N1845(orf name)|uniprotkb:YNL135C(locus name)|uniprotkb:FPR1(gene name)|psi-mi:FPR1(display_short)|uniprotkb:FKB1(gene name synonym)|uniprotkb:Peptidyl-prolyl cis-trans isomerase(gene name synonym)|uniprotkb:Rapamycin-binding protein(gene name synonym)	psi-mi:wbp11_human(display_long)|uniprotkb:SH3 domain-binding protein SNP70(gene name synonym)|uniprotkb:Npw38-binding protein(gene name synonym)|uniprotkb:WBP11(gene name)|psi-mi:WBP11(display_short)|uniprotkb:NPWBP(gene name synonym)|uniprotkb:SNP70(gene name synonym)|uniprotkb:SIPP1(gene name synonym)|uniprotkb:Splicing factor that interacts with PQBP-1 and PP1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11539280|imex:IM-24995-1779	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014264.1|sgd:S000005079|dip:DIP-1263N|mint:P20081|ensemblfungi:YNL135C(gene)|ensemblfungi:YNL135C_mRNA(transcript)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005527"(macrolide binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006325"(chromatin organization)|go:"GO:0006457"(protein folding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:1901710"(regulation of homoserine biosynthetic process)|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)|rcsb pdb:1YAT|sgd:YNL135C(identity)	rcsb pdb:7ABG|reactome:R-HSA-72163|ensembl:ENSG00000084463(gene)|ensembl:ENST00000261167(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045292"(mRNA cis splicing, via spliceosome)|go:"GO:0050699"(WW domain binding)|interpro:IPR019007|mint:Q9Y2W2|rcsb pdb:7ABF|refseq:NP_057396.1|entrezgene/locuslink:51729(identity)	-	crc64:65C134830D300C06	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:8afvGSk+mPghtqkVoWd2rHJXXhQ559292	rogid:qE03bpSsQiJouJbn6ISt8DnD/pA9606	intact-crc:D870687FD5E52F56|rigid:Yp9hgufBgRCAaH1qCnbXNzwHKb0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P20081	uniprotkb:Q8N684-3	intact:EBI-6961|uniprotkb:D6W147|ensemblfungi:YNL135C	intact:EBI-11523759|ensembl:ENSP00000345412	psi-mi:fkbp_yeast(display_long)|uniprotkb:RBP1(gene name synonym)|uniprotkb:N1213(orf name)|uniprotkb:N1845(orf name)|uniprotkb:YNL135C(locus name)|uniprotkb:FPR1(gene name)|psi-mi:FPR1(display_short)|uniprotkb:FKB1(gene name synonym)|uniprotkb:Peptidyl-prolyl cis-trans isomerase(gene name synonym)|uniprotkb:Rapamycin-binding protein(gene name synonym)	psi-mi:q8n684-3(display_long)|uniprotkb:Cleavage factor Im complex 59 kDa subunit(gene name synonym)|uniprotkb:CPSF7(gene name)|psi-mi:CPSF7(display_short)|uniprotkb:Cleavage and polyadenylation specificity factor 59 kDa subunit(gene name synonym)|uniprotkb:Pre-mRNA cleavage factor Im 59 kDa subunit(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11539269|imex:IM-24995-1778	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014264.1|sgd:S000005079|dip:DIP-1263N|mint:P20081|ensemblfungi:YNL135C(gene)|ensemblfungi:YNL135C_mRNA(transcript)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005527"(macrolide binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006325"(chromatin organization)|go:"GO:0006457"(protein folding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:1901710"(regulation of homoserine biosynthetic process)|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)|rcsb pdb:1YAT|sgd:YNL135C(identity)	intact:EBI-746909(isoform-parent)|ensembl:ENSG00000149532(gene)|ensembl:ENST00000340437(transcript)|uniprotkb:Q8N684-3(isoform-parent)|entrezgene/locuslink:79869(identity)	-	crc64:65C134830D300C06	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:8afvGSk+mPghtqkVoWd2rHJXXhQ559292	rogid:hnk6o9HBKsdIRWKRuEdjdByVKxM9606	intact-crc:D2327586D818CED7|rigid:eeeSKW6VR6Te456svsfGznIKuDY	false	-	sufficient binding region:44-514	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q08379	uniprotkb:P20676	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	intact:EBI-12392|ensemblfungi:YOR098C|uniprotkb:D6W2F9	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:nup1_yeast(display_long)|uniprotkb:NUP1(gene name)|psi-mi:NUP1(display_short)|uniprotkb:YOR098C(locus name)|uniprotkb:YOR3182C(orf name)|uniprotkb:Nuclear pore protein NUP1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11539334|imex:IM-24995-1785	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N|entrezgene/locuslink:2801(identity)	ensemblfungi:YOR098C(gene)|ensemblfungi:YOR098C_mRNA(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000972"(transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0005643"(nuclear pore)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0044615"(nuclear pore nuclear basket)|interpro:IPR026054|rcsb pdb:4C31|rcsb pdb:4MBE|rcsb pdb:5OWU|go:"GO:0006607"(NLS-bearing protein import into nucleus)|refseq:NP_014741.1|sgd:S000005624|mint:P20676|dip:DIP-81N|sgd:YOR098C(identity)	-	-	crc64:4AC23567D2FB53CC	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2017/05/26	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	rogid:X1AjTIzoXjQ7vXlKzI88m7xfu6w559292	intact-crc:FDBB78B0B2C6C909|rigid:NiqQjTaP3EVF+eZ72FYDbdhmnC8	false	sufficient binding region:383-1002	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96IK5	uniprotkb:P20459	intact:EBI-2548508|ensembl:ENSP00000282570|uniprotkb:Q9H826|uniprotkb:Q9H8V7|uniprotkb:Q9H927	intact:EBI-8915|uniprotkb:E9P8T6|ensemblfungi:YJR007W|uniprotkb:D6VWI2	psi-mi:gmcl1_human(display_long)|uniprotkb:GMCL1(gene name)|psi-mi:GMCL1(display_short)|uniprotkb:GCL(gene name synonym)|uniprotkb:BTBD13(gene name synonym)|uniprotkb:SPATA29(gene name synonym)|uniprotkb:Spermatogenesis-associated protein 29(gene name synonym)	psi-mi:if2a_yeast(display_long)|uniprotkb:SUI2(gene name)|psi-mi:SUI2(display_short)|uniprotkb:TIF211(gene name synonym)|uniprotkb:YJR007W(locus name)|uniprotkb:J1429(orf name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11539325|imex:IM-24995-1784	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000087338(gene)|ensembl:ENST00000282570(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0007281"(germ cell development)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016363"(nuclear matrix)|go:"GO:0042802"(identical protein binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR043380|refseq:NP_848526.1|entrezgene/locuslink:64395(identity)	interpro:IPR022967|interpro:IPR024054|interpro:IPR024055|interpro:IPR044126|rcsb pdb:1Q46|rcsb pdb:2A19|rcsb pdb:2A1A|rcsb pdb:3J81|rcsb pdb:3JAP|rcsb pdb:3JAQ|rcsb pdb:6FYX|rcsb pdb:6FYY|rcsb pdb:6GSM|rcsb pdb:6GSN|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6JLY|rcsb pdb:6JLZ|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-156827|reactome:R-SCE-381042|reactome:R-SCE-72649|reactome:R-SCE-72695|reactome:R-SCE-72702|reactome:R-SCE-72731|ensemblfungi:YJR007W(gene)|ensemblfungi:YJR007W_mRNA(transcript)|go:"GO:0001731"(formation of translation preinitiation complex)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005850"(eukaryotic translation initiation factor 2 complex)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0043022"(ribosome binding)|go:"GO:0043614"(multi-eIF complex)|interpro:IPR003029(S1, RNA binding)|interpro:IPR011488(Eukaryotic translation initiation factor 2, alpha subunit)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|refseq:NP_012540.3|sgd:S000003767|mint:P20459|dip:DIP-2327N|sgd:YJR007W(identity)	-	-	crc64:AF4F1C80303A4E98	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:ED8yqySVu7BWxpw3DUSNBZSQWrk9606	rogid:9/iGImP9/c8HSYwgmItME27z7lE559292	intact-crc:BF92650B3E719E6B|rigid:IoMb+WSQ/W6Elnkz1GDET4tvspo	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P20133	uniprotkb:Q9UJC3	intact:EBI-3559|uniprotkb:P32433|uniprotkb:D6W4H7|ensemblfungi:YPR176C	intact:EBI-746704|uniprotkb:O60561|uniprotkb:Q5TG44|uniprotkb:A8MU44|uniprotkb:B4DX15|uniprotkb:A8K8E9|intact:EBI-10969618|ensembl:ENSP00000360252	psi-mi:pgtb2_yeast(display_long)|uniprotkb:Geranylgeranyl transferase type II subunit beta(gene name synonym)|uniprotkb:Type II protein geranyl-geranyltransferase subunit beta(gene name synonym)|uniprotkb:YPT1/SEC4 proteins geranylgeranyltransferase subunit beta(gene name synonym)|uniprotkb:BET2(gene name)|psi-mi:BET2(display_short)|uniprotkb:YPR176C(locus name)|uniprotkb:P9705.12(orf name)	psi-mi:hook1_human(display_long)|uniprotkb:HOOK1(gene name)|psi-mi:HOOK1(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11539316|imex:IM-24995-1783	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015502.1|sgd:S000006380|reactome:R-SCE-6803205|reactome:R-SCE-8873719|dip:DIP-2214N|ensemblfungi:YPR176C(gene)|ensemblfungi:YPR176C_mRNA(transcript)|go:"GO:0004663"(Rab geranylgeranyltransferase activity)|go:"GO:0005829"(cytosol)|go:"GO:0005968"(Rab-protein geranylgeranyltransferase complex)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0008270"(zinc ion binding)|go:"GO:0018342"(protein prenylation)|go:"GO:0018344"(protein geranylgeranylation)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001330(Prenyltransferase/squalene oxidase)|interpro:IPR008930(Terpenoid cylases/protein prenyltransferase alpha-alpha toroid)|interpro:IPR026873|sgd:YPR176C(identity)	refseq:NP_056972.1|ensembl:ENSG00000134709(gene)|ensembl:ENST00000371208(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0007030"(Golgi organization)|go:"GO:0007032"(endosome organization)|go:"GO:0007040"(lysosome organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0015031"(protein transport)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0051959"(dynein light intermediate chain binding)|go:"GO:0070695"(FHF complex)|go:"GO:1905198"(manchette assembly)|go:"GO:1905719"(protein localization to perinuclear region of cytoplasm)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR008636(HOOK)|interpro:IPR036872|interpro:IPR043936|mint:Q9UJC3|entrezgene/locuslink:51361(identity)	-	crc64:6A9C44DFBE62AAFC	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Fxribu0N2yK6IA2GZDfO0YmqLAo559292	rogid:QOcYbuKfnNIlNKzos5v+0+A2h3I9606	intact-crc:64EBE978B02D2CB7|rigid:FQ1SnE45bUOCAXYw9TLiJyl8nCw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9HD26-2	uniprotkb:P21651	intact:EBI-11102276|ensembl:ENSP00000052569	intact:EBI-10742|ensemblfungi:YJR021C|uniprotkb:D6VWJ5	psi-mi:q9hd26-2(display_long)|uniprotkb:GOPC(gene name)|psi-mi:GOPC(display_short)|uniprotkb:CAL(gene name synonym)|uniprotkb:CFTR-associated ligand(gene name synonym)|uniprotkb:FIG(gene name synonym)|uniprotkb:Fused in glioblastoma(gene name synonym)|uniprotkb:PDZ protein interacting specifically with TC10(gene name synonym)	psi-mi:re107_yeast(display_long)|uniprotkb:MER2(gene name synonym)|uniprotkb:J1462(orf name)|uniprotkb:YJR021C(locus name)|uniprotkb:REC107(gene name)|psi-mi:REC107(display_short)|uniprotkb:Meiotic recombination protein 2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11539363|imex:IM-24995-1788	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000047932(gene)|ensembl:ENST00000052569(transcript)|intact:EBI-349832(isoform-parent)|uniprotkb:Q9HD26-2(isoform-parent)|entrezgene/locuslink:57120(identity)	ensemblfungi:YJR021C(gene)|ensemblfungi:YJR021C_mRNA(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0042802"(identical protein binding)|interpro:IPR015159(Mer2)|sgd:S000003782|refseq:NP_012555.1|dip:DIP-5265N|sgd:YJR021C(identity)	-	-	crc64:46F426AC0DFDFAD0	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:QoEGY54FfmwTrpGVMQN9ASGPgVI9606	rogid:v9kR3rBIptwb/cZE7B5IMAkYWKc559292	intact-crc:2AF5E7E18D5035AE|rigid:GfCz05Or0PqXzJLkD4GZ2URvuhY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96IK5	uniprotkb:P21651	intact:EBI-2548508|ensembl:ENSP00000282570|uniprotkb:Q9H826|uniprotkb:Q9H8V7|uniprotkb:Q9H927	intact:EBI-10742|ensemblfungi:YJR021C|uniprotkb:D6VWJ5	psi-mi:gmcl1_human(display_long)|uniprotkb:GMCL1(gene name)|psi-mi:GMCL1(display_short)|uniprotkb:GCL(gene name synonym)|uniprotkb:BTBD13(gene name synonym)|uniprotkb:SPATA29(gene name synonym)|uniprotkb:Spermatogenesis-associated protein 29(gene name synonym)	psi-mi:re107_yeast(display_long)|uniprotkb:MER2(gene name synonym)|uniprotkb:J1462(orf name)|uniprotkb:YJR021C(locus name)|uniprotkb:REC107(gene name)|psi-mi:REC107(display_short)|uniprotkb:Meiotic recombination protein 2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11539354|imex:IM-24995-1787	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000087338(gene)|ensembl:ENST00000282570(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0007281"(germ cell development)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016363"(nuclear matrix)|go:"GO:0042802"(identical protein binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR043380|refseq:NP_848526.1|entrezgene/locuslink:64395(identity)	ensemblfungi:YJR021C(gene)|ensemblfungi:YJR021C_mRNA(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0042802"(identical protein binding)|interpro:IPR015159(Mer2)|sgd:S000003782|refseq:NP_012555.1|dip:DIP-5265N|sgd:YJR021C(identity)	-	-	crc64:46F426AC0DFDFAD0	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:ED8yqySVu7BWxpw3DUSNBZSQWrk9606	rogid:v9kR3rBIptwb/cZE7B5IMAkYWKc559292	intact-crc:83D63A5A2EC165AC|rigid:bOFaBcDqb6RObTx/Mdo/KzneuAU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P51116	uniprotkb:P20676	intact:EBI-740459|uniprotkb:Q8WUM2|uniprotkb:Q86V09|uniprotkb:B2R9M2|uniprotkb:D3DTQ1|ensembl:ENSP00000250113	intact:EBI-12392|ensemblfungi:YOR098C|uniprotkb:D6W2F9	psi-mi:fxr2_human(display_long)|uniprotkb:FXR2(gene name)|psi-mi:FXR2(display_short)|uniprotkb:FMR1L2(gene name synonym)	psi-mi:nup1_yeast(display_long)|uniprotkb:NUP1(gene name)|psi-mi:NUP1(display_short)|uniprotkb:YOR098C(locus name)|uniprotkb:YOR3182C(orf name)|uniprotkb:Nuclear pore protein NUP1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11539345|imex:IM-24995-1786	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR004087(K Homology)|refseq:NP_004851.2|ensembl:ENSG00000129245(gene)|ensembl:ENST00000250113(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0044326"(dendritic spine neck)|go:"GO:0045182"(translation regulator activity)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0098793"(presynapse)|go:"GO:1902737"(dendritic filopodium)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|interpro:IPR004088(K Homology, type 1)|interpro:IPR008395(Agenet)|interpro:IPR022034|interpro:IPR032172|interpro:IPR036612|interpro:IPR040148|interpro:IPR040472|interpro:IPR041560|mint:P51116|rcsb pdb:3H8Z|entrezgene/locuslink:9513(identity)	ensemblfungi:YOR098C(gene)|ensemblfungi:YOR098C_mRNA(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000972"(transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0005643"(nuclear pore)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0044615"(nuclear pore nuclear basket)|interpro:IPR026054|rcsb pdb:4C31|rcsb pdb:4MBE|rcsb pdb:5OWU|go:"GO:0006607"(NLS-bearing protein import into nucleus)|refseq:NP_014741.1|sgd:S000005624|mint:P20676|dip:DIP-81N|sgd:YOR098C(identity)	-	-	crc64:4AC23567D2FB53CC	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:NnYgyzD2NRGIO1ZHukr5qy44qRE9606	rogid:X1AjTIzoXjQ7vXlKzI88m7xfu6w559292	intact-crc:B51C38EAB79F3ADA|rigid:EiytHB1z8daib+C292mqC/9Yc/o	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P22217	uniprotkb:Q96D03	intact:EBI-19607|uniprotkb:D6VY45|ensemblfungi:YLR043C	intact:EBI-742054|uniprotkb:B2R7C3|ensembl:ENSP00000354830	psi-mi:trx1_yeast(display_long)|uniprotkb:TRX1(gene name)|psi-mi:TRX1(display_short)|uniprotkb:TRX2(gene name synonym)|uniprotkb:YLR043C(locus name)|uniprotkb:Thioredoxin I(gene name synonym)|uniprotkb:Thioredoxin-2(gene name synonym)	psi-mi:ddt4l_human(display_long)|uniprotkb:Protein regulated in development and DNA damage response 2(gene name synonym)|uniprotkb:HIF-1 responsive protein RTP801-like(gene name synonym)|uniprotkb:DDIT4L(gene name)|psi-mi:DDIT4L(display_short)|uniprotkb:REDD2(gene name synonym)|uniprotkb:RTP801L(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11539409|imex:IM-24995-1793	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013144.1|sgd:S000004033|interpro:IPR005746(Thioredoxin)|interpro:IPR017937|interpro:IPR013766(Thioredoxin domain)|ensemblfungi:YLR043C(gene)|ensemblfungi:YLR043C_mRNA(transcript)|go:"GO:0000011"(vacuole inheritance)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0009263"(deoxyribonucleotide biosynthetic process)|go:"GO:0015031"(protein transport)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0015036"(disulfide oxidoreductase activity)|go:"GO:0042144"(vacuole fusion, non-autophagic)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0080058"(protein deglutathionylation)|rcsb pdb:2I9H|rcsb pdb:2N5A|rcsb pdb:2N5B|rcsb pdb:3F3Q|rcsb pdb:3F3R|go:"GO:0006662"(glycerol ether metabolic process)|mint:P22217|interpro:IPR036249|sgd:YLR043C(identity)	refseq:NP_660287.1|ensembl:ENSG00000145358(gene)|ensembl:ENST00000273990(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0009968"(negative regulation of signal transduction)|interpro:IPR012918(RTP801, C-terminal)|interpro:IPR038281|entrezgene/locuslink:115265(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:HTTjl3NGIuQllhjAI5NASyqqIlc559292	rogid:DHXiWraTchl3LZgh/lXlUr3LKwE9606	intact-crc:97AB85FD20E8BE6C|rigid:Yyhl69PcyPOAWqvyRxqGPz4VrB8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P22215	uniprotkb:Q15437	intact:EBI-17397|uniprotkb:D6W307|ensemblfungi:YOR307C	intact:EBI-742673|uniprotkb:Q5W183|uniprotkb:Q9BS15|uniprotkb:Q9BSI2|uniprotkb:Q9H1D7|intact:EBI-1048165|uniprotkb:Q503A9|uniprotkb:D3DW33|ensembl:ENSP00000262544|ensembl:ENSP00000338844|ensembl:ENSP00000366685|ensembl:ENSP00000497473	psi-mi:sly41_yeast(display_long)|uniprotkb:O5663(orf name)|uniprotkb:YOR307C(locus name)|uniprotkb:SLY41(gene name)|psi-mi:SLY41(display_short)	psi-mi:sc23b_human(display_long)|uniprotkb:SEC23-related protein B(gene name synonym)|uniprotkb:SEC23B(gene name)|psi-mi:SEC23B(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11539400|imex:IM-24995-1792	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014952.1|sgd:S000005834|ensemblfungi:YOR307C(gene)|ensemblfungi:YOR307C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0015297"(antiporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0089721"(phosphoenolpyruvate transmembrane transporter activity)|go:"GO:1990536"(phosphoenolpyruvate transmembrane import into Golgi lumen)|interpro:IPR004696(Tpt phosphate/phosphoenolpyruvate translocator)|interpro:IPR004853(Protein of unknown function DUF250)|dip:DIP-2919N|sgd:YOR307C(identity)	refseq:NP_001166216.1|refseq:NP_006354.2|refseq:NP_116780.1|refseq:NP_116781.1|ensembl:ENSG00000101310(gene)|ensembl:ENST00000262544(transcript)|ensembl:ENST00000336714(transcript)|ensembl:ENST00000377465(transcript)|ensembl:ENST00000650089(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008270"(zinc ion binding)|go:"GO:0012505"(endomembrane system)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0090110"(COPII-coated vesicle cargo loading)|go:"GO:0070971"(endoplasmic reticulum exit site)|interpro:IPR006895(Zinc finger, Sec23/Sec24-type)|interpro:IPR006896(Sec23/Sec24 trunk region)|interpro:IPR006900(Sec23/Sec24 helical region)|interpro:IPR007123(Gelsolin region)|interpro:IPR012990(Sec23/Sec24 beta-sandwich)|interpro:IPR029006|interpro:IPR036174|interpro:IPR036175|interpro:IPR036180|interpro:IPR036465|interpro:IPR037364|interpro:IPR037550|mint:Q15437|refseq:XP_016883082.1|entrezgene/locuslink:10483(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:ZlrKRnUmlnFI2o8e365rgea//gA559292	rogid:+3KZ/1jjziSgJRcr81Axquofkl49606	intact-crc:544368F6141C3EC1|rigid:CEqncGa+9X+oy3T+p0p0cAwbhdo	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9HCM9-2	uniprotkb:P21734	intact:EBI-11523450|ensembl:ENSP00000365847|ensembl:ENSP00000373095|ensembl:ENSP00000373097|ensembl:ENSP00000379797|ensembl:ENSP00000379800|ensembl:ENSP00000383486|ensembl:ENSP00000387445|ensembl:ENSP00000389198|ensembl:ENSP00000389852|ensembl:ENSP00000392130|ensembl:ENSP00000394353|ensembl:ENSP00000396986|ensembl:ENSP00000398956|ensembl:ENSP00000401071|ensembl:ENSP00000401184|ensembl:ENSP00000404340|ensembl:ENSP00000404904|ensembl:ENSP00000411582|ensembl:ENSP00000412743|ensembl:ENSP00000414525|ensembl:ENSP00000415259	intact:EBI-19717|uniprotkb:D6VSF9|ensemblfungi:YDR177W	psi-mi:q9hcm9-2(display_long)|uniprotkb:TRIM39(gene name)|psi-mi:TRIM39(display_short)|uniprotkb:RING finger protein 23(gene name synonym)|uniprotkb:RNF23(gene name synonym)|uniprotkb:TFP(gene name synonym)|uniprotkb:Testis-abundant finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 39(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM39(gene name synonym)|uniprotkb:TIM39beta(isoform synonym)	psi-mi:ubc1_yeast(display_long)|uniprotkb:UBC1(gene name)|psi-mi:UBC1(display_short)|uniprotkb:YDR177W(locus name)|uniprotkb:YD9395.10(orf name)|uniprotkb:Ubiquitin-protein ligase(gene name synonym)|uniprotkb:Ubiquitin carrier protein(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-24 kDa(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11539390|imex:IM-24995-1791	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-739510(isoform-parent)|ensembl:ENSG00000204599(gene)|ensembl:ENSG00000206495(gene)|ensembl:ENSG00000224994(gene)|ensembl:ENSG00000226437(gene)|ensembl:ENSG00000229929(gene)|ensembl:ENSG00000230308(gene)|ensembl:ENSG00000232839(gene)|ensembl:ENST00000376659(transcript)|ensembl:ENST00000383601(transcript)|ensembl:ENST00000383603(transcript)|ensembl:ENST00000396548(transcript)|ensembl:ENST00000396551(transcript)|ensembl:ENST00000400644(transcript)|ensembl:ENST00000414015(transcript)|ensembl:ENST00000419790(transcript)|ensembl:ENST00000430502(transcript)|ensembl:ENST00000431272(transcript)|ensembl:ENST00000433900(transcript)|ensembl:ENST00000438076(transcript)|ensembl:ENST00000438859(transcript)|ensembl:ENST00000440117(transcript)|ensembl:ENST00000443109(transcript)|ensembl:ENST00000446397(transcript)|ensembl:ENST00000449318(transcript)|ensembl:ENST00000450778(transcript)|ensembl:ENST00000451132(transcript)|ensembl:ENST00000452705(transcript)|ensembl:ENST00000458607(transcript)|uniprotkb:Q9HCM9-2(isoform-parent)|entrezgene/locuslink:56658(identity)	sgd:S000002584|ensemblfungi:YDR177W(gene)|ensemblfungi:YDR177W_mRNA(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016050"(vesicle organization)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070628"(proteasome binding)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR009060(UBA-like)|interpro:IPR015368(Ubiquitin-conjugating enzyme, C-terminal fungi)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1FXT|rcsb pdb:1FZY|rcsb pdb:1TTE|reactome:R-SCE-8866652|reactome:R-SCE-983168|refseq:NP_010462.3|dip:DIP-6594N|mint:P21734|sgd:YDR177W(identity)	-	-	crc64:899CC397A1285145	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:UfSn2+IVRxtGomVeDGdZpL7mz5I9606	rogid:3N1WHZJcgMeK0OglGpGI2m4XU8Q559292	intact-crc:E3B8D3C648936643|rigid:diOzZx6LRU1fphQaRrHjmYvYAd0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9C040	uniprotkb:P21734	intact:EBI-749840|uniprotkb:O60272|uniprotkb:Q9BSI9|uniprotkb:Q9UFZ1|ensembl:ENSP00000415812|ensembl:ENSP00000501586|ensembl:ENSP00000501612|ensembl:ENSP00000501652|ensembl:ENSP00000501662|ensembl:ENSP00000501792|ensembl:ENSP00000501822|ensembl:ENSP00000501951|ensembl:ENSP00000501994|ensembl:ENSP00000502089|ensembl:ENSP00000502114|ensembl:ENSP00000502159|ensembl:ENSP00000502273|ensembl:ENSP00000502348|ensembl:ENSP00000502356|ensembl:ENSP00000502519|ensembl:ENSP00000502543|ensembl:ENSP00000502676|uniprotkb:D3DP09	intact:EBI-19717|uniprotkb:D6VSF9|ensemblfungi:YDR177W	psi-mi:trim2_human(display_long)|uniprotkb:RING finger protein 86(gene name synonym)|uniprotkb:TRIM2(gene name)|psi-mi:TRIM2(display_short)|uniprotkb:KIAA0517(gene name synonym)|uniprotkb:RNF86(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM2(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase TRIM2(gene name synonym)	psi-mi:ubc1_yeast(display_long)|uniprotkb:UBC1(gene name)|psi-mi:UBC1(display_short)|uniprotkb:YDR177W(locus name)|uniprotkb:YD9395.10(orf name)|uniprotkb:Ubiquitin-protein ligase(gene name synonym)|uniprotkb:Ubiquitin carrier protein(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-24 kDa(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11539381|imex:IM-24995-1790	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001123539.1|refseq:NP_056086.2|ensembl:ENST00000437508(transcript)|ensembl:ENST00000674874(transcript)|ensembl:ENST00000674876(transcript)|ensembl:ENSG00000109654(gene)|refseq:XP_016863433.1|refseq:XP_016863434.1|refseq:XP_016863437.1|refseq:XP_016863438.1|refseq:XP_016863439.1|refseq:XP_016863440.1|refseq:XP_016863441.1|ensembl:ENST00000674976(transcript)|ensembl:ENST00000675054(transcript)|ensembl:ENST00000675159(transcript)|ensembl:ENST00000675293(transcript)|ensembl:ENST00000675315(transcript)|ensembl:ENST00000675384(transcript)|ensembl:ENST00000675745(transcript)|ensembl:ENST00000675835(transcript)|ensembl:ENST00000676172(transcript)|ensembl:ENST00000676252(transcript)|ensembl:ENST00000676264(transcript)|ensembl:ENST00000676348(transcript)|ensembl:ENST00000676374(transcript)|ensembl:ENST00000676423(transcript)|ensembl:ENST00000676458(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017868|interpro:IPR017907|interpro:IPR027370|mint:Q9C040|rcsb pdb:7B2R|reactome:R-HSA-877300|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001258(NHL repeat)|interpro:IPR001298(Filamin/ABP280 repeat)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR013017(NHL repeat, subgroup)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|entrezgene/locuslink:23321(identity)	sgd:S000002584|ensemblfungi:YDR177W(gene)|ensemblfungi:YDR177W_mRNA(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016050"(vesicle organization)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070628"(proteasome binding)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR009060(UBA-like)|interpro:IPR015368(Ubiquitin-conjugating enzyme, C-terminal fungi)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1FXT|rcsb pdb:1FZY|rcsb pdb:1TTE|reactome:R-SCE-8866652|reactome:R-SCE-983168|refseq:NP_010462.3|dip:DIP-6594N|mint:P21734|sgd:YDR177W(identity)	-	-	crc64:899CC397A1285145	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:vcyraMhX0YqrCi9PXhvlJ7QqhGs9606	rogid:3N1WHZJcgMeK0OglGpGI2m4XU8Q559292	intact-crc:731CBB8200D94924|rigid:U5sD2HuFEJJxijpgqcIgCEoEveU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P21734	uniprotkb:O95376	intact:EBI-19717|uniprotkb:D6VSF9|ensemblfungi:YDR177W	intact:EBI-711158|uniprotkb:Q9HBZ6|uniprotkb:Q9UEM9|ensembl:ENSP00000348769|ensembl:ENSP00000403222	psi-mi:ubc1_yeast(display_long)|uniprotkb:UBC1(gene name)|psi-mi:UBC1(display_short)|uniprotkb:YDR177W(locus name)|uniprotkb:YD9395.10(orf name)|uniprotkb:Ubiquitin-protein ligase(gene name synonym)|uniprotkb:Ubiquitin carrier protein(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-24 kDa(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme 1(gene name synonym)	psi-mi:ari2_human(display_long)|uniprotkb:Triad1 protein(gene name synonym)|uniprotkb:ARIH2(gene name)|psi-mi:ARIH2(display_short)|uniprotkb:ARI2(gene name synonym)|uniprotkb:TRIAD1(gene name synonym)|uniprotkb:HT005(orf name)|uniprotkb:RING-type E3 ubiquitin transferase ARIH2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11539372|imex:IM-24995-1789	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002584|ensemblfungi:YDR177W(gene)|ensemblfungi:YDR177W_mRNA(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016050"(vesicle organization)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070628"(proteasome binding)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR009060(UBA-like)|interpro:IPR015368(Ubiquitin-conjugating enzyme, C-terminal fungi)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1FXT|rcsb pdb:1FZY|rcsb pdb:1TTE|reactome:R-SCE-8866652|reactome:R-SCE-983168|refseq:NP_010462.3|dip:DIP-6594N|mint:P21734|sgd:YDR177W(identity)	refseq:NP_001304262.1|refseq:NP_001304263.1|refseq:NP_006312.1|ensembl:ENSG00000177479(gene)|ensembl:ENST00000356401(transcript)|ensembl:ENST00000449376(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0048588"(developmental cell growth)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0071425"(hematopoietic stem cell proliferation)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002867(Zinc finger, C6HC-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR031126|interpro:IPR031127|interpro:IPR044066|reactome:R-HSA-983168|refseq:XP_016861020.1|refseq:XP_016861021.1|entrezgene/locuslink:10425(identity)	-	crc64:899CC397A1285145	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:3N1WHZJcgMeK0OglGpGI2m4XU8Q559292	rogid:536Qu2bpbptYcIhxoeLJNTErLTM9606	intact-crc:C96DAC8CD0E87C1B|rigid:j7z9megFLIB4albVuagtbf0OQ80	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P23059	uniprotkb:Q13422-7	intact:EBI-10950|ensemblfungi:YCR020C-A|uniprotkb:D6VR29	intact:EBI-11522367|ensembl:ENSP00000352123|ensembl:ENSP00000413025	psi-mi:naa38_yeast(display_long)|uniprotkb:MAK31(gene name)|psi-mi:MAK31(display_short)|uniprotkb:YCR020C-A(locus name)|uniprotkb:YCR20C-A(orf name)|uniprotkb:L-A virus GAG protein N-acetyltransferase subunit MAK31(gene name synonym)|uniprotkb:Maintenance of killer protein 31(gene name synonym)|uniprotkb:NAA38(gene name synonym)|uniprotkb:N-terminal acetyltransferase C complex subunit MAK31(gene name synonym)	psi-mi:q13422-7(display_long)|uniprotkb:IKZF1(gene name)|psi-mi:IKZF1(display_short)|uniprotkb:IK1(gene name synonym)|uniprotkb:IKAROS(gene name synonym)|uniprotkb:Ikaros family zinc finger protein 1(gene name synonym)|uniprotkb:LYF1(gene name synonym)|uniprotkb:Lymphoid transcription factor LyF-1(gene name synonym)|uniprotkb:ZNFN1A1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11539445|imex:IM-24995-1797	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YCR020C-A(gene)|ensemblfungi:YCR020C-A_mRNA(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005688"(U6 snRNP)|go:"GO:0005829"(cytosol)|go:"GO:0006474"(N-terminal protein amino acid acetylation)|go:"GO:0016070"(RNA metabolic process)|go:"GO:0031417"(NatC complex)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071011"(precatalytic spliceosome)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR034110|rcsb pdb:6YGA|rcsb pdb:6YGB|rcsb pdb:6YGC|rcsb pdb:6YGD|refseq:NP_009948.1|sgd:S000000614|mint:P23059|dip:DIP-1429N|sgd:YCR020C-A(identity)	intact:EBI-745305(isoform-parent)|ensembl:ENSG00000185811(gene)|ensembl:ENST00000359197(transcript)|ensembl:ENST00000439701(transcript)|uniprotkb:Q13422-7(isoform-parent)|entrezgene/locuslink:10320(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:VUwG0xxj0NeyZKANRYCAgJGuqs8559292	rogid:ou/ovXYoMneBNVp4pj38VxenfyY9606	intact-crc:80143AFF68C60AEE|rigid:VoFNN/v7hsuD62HSV31gHLpXIy8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96D03	uniprotkb:P22803	intact:EBI-742054|uniprotkb:B2R7C3|ensembl:ENSP00000354830	intact:EBI-19598|uniprotkb:D6VUZ2|ensemblfungi:YGR209C	psi-mi:ddt4l_human(display_long)|uniprotkb:Protein regulated in development and DNA damage response 2(gene name synonym)|uniprotkb:HIF-1 responsive protein RTP801-like(gene name synonym)|uniprotkb:DDIT4L(gene name)|psi-mi:DDIT4L(display_short)|uniprotkb:REDD2(gene name synonym)|uniprotkb:RTP801L(gene name synonym)	psi-mi:trx2_yeast(display_long)|uniprotkb:TRX2(gene name)|psi-mi:TRX2(display_short)|uniprotkb:TRX1(gene name synonym)|uniprotkb:G7746(orf name)|uniprotkb:YGR209C(locus name)|uniprotkb:Thioredoxin II(gene name synonym)|uniprotkb:Thioredoxin-1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11539436|imex:IM-24995-1796	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_660287.1|ensembl:ENSG00000145358(gene)|ensembl:ENST00000273990(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0009968"(negative regulation of signal transduction)|interpro:IPR012918(RTP801, C-terminal)|interpro:IPR038281|entrezgene/locuslink:115265(identity)	sgd:S000003441|go:"GO:0009263"(deoxyribonucleotide biosynthetic process)|go:"GO:0015031"(protein transport)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0015036"(disulfide oxidoreductase activity)|go:"GO:0042144"(vacuole fusion, non-autophagic)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0080058"(protein deglutathionylation)|interpro:IPR005746(Thioredoxin)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017937|interpro:IPR036249|rcsb pdb:2FA4|rcsb pdb:2HSY|rcsb pdb:3PIN|rcsb pdb:4DSS|rcsb pdb:7BVV|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|ensemblfungi:YGR209C(gene)|ensemblfungi:YGR209C_mRNA(transcript)|go:"GO:0000011"(vacuole inheritance)|go:"GO:0000103"(sulfate assimilation)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006662"(glycerol ether metabolic process)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|refseq:NP_011725.3|dip:DIP-5552N|mint:P22803|sgd:YGR209C(identity)	-	-	crc64:071503762C90D451	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:DHXiWraTchl3LZgh/lXlUr3LKwE9606	rogid:pRt9fGROPXW+o4g6ynOmCDiclFk559292	intact-crc:932578A0AFB8EE61|rigid:8t0PJQHcNgIXZyZ5Zhffs+CPVkg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P22803	uniprotkb:Q8TBB1	intact:EBI-19598|uniprotkb:D6VUZ2|ensemblfungi:YGR209C	intact:EBI-739832|uniprotkb:Q4W5K7|uniprotkb:Q8N4C2|uniprotkb:Q96MJ7|uniprotkb:Q9BY20|ensembl:ENSP00000263925	psi-mi:trx2_yeast(display_long)|uniprotkb:TRX2(gene name)|psi-mi:TRX2(display_short)|uniprotkb:TRX1(gene name synonym)|uniprotkb:G7746(orf name)|uniprotkb:YGR209C(locus name)|uniprotkb:Thioredoxin II(gene name synonym)|uniprotkb:Thioredoxin-1(gene name synonym)	psi-mi:lnx1_human(display_long)|uniprotkb:LNX1(gene name)|psi-mi:LNX1(display_short)|uniprotkb:LNX(gene name synonym)|uniprotkb:Numb-binding protein 1(gene name synonym)|uniprotkb:Ligand of Numb-protein X 1(gene name synonym)|uniprotkb:PDZ domain-containing RING finger protein 2(gene name synonym)|uniprotkb:PDZRN2(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase LNX(gene name synonym)|uniprotkb:UNQ574/PRO1136(orf name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11539427|imex:IM-24995-1795	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003441|go:"GO:0009263"(deoxyribonucleotide biosynthetic process)|go:"GO:0015031"(protein transport)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0015036"(disulfide oxidoreductase activity)|go:"GO:0042144"(vacuole fusion, non-autophagic)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0080058"(protein deglutathionylation)|interpro:IPR005746(Thioredoxin)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017937|interpro:IPR036249|rcsb pdb:2FA4|rcsb pdb:2HSY|rcsb pdb:3PIN|rcsb pdb:4DSS|rcsb pdb:7BVV|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|ensemblfungi:YGR209C(gene)|ensemblfungi:YGR209C_mRNA(transcript)|go:"GO:0000011"(vacuole inheritance)|go:"GO:0000103"(sulfate assimilation)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006662"(glycerol ether metabolic process)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|refseq:NP_011725.3|dip:DIP-5552N|mint:P22803|sgd:YGR209C(identity)	refseq:NP_001119800.1|refseq:NP_116011.2|refseq:XP_005265842.1|refseq:XP_016864265.1|ensembl:ENSG00000072201(gene)|ensembl:ENST00000263925(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR036034|mint:Q8TBB1|rcsb pdb:3B76|rcsb pdb:5H7R|rcsb pdb:5H7S|reactome:R-HSA-983168|entrezgene/locuslink:84708(identity)	-	crc64:071503762C90D451	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:pRt9fGROPXW+o4g6ynOmCDiclFk559292	rogid:tWvePnVxh9yxWl8nQd3KZhCSKKo9606	intact-crc:F547327609E992CC|rigid:MqEiw6U/WmcKG7kZPaq/vJFAgWQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P22354	uniprotkb:O95273	intact:EBI-15536|uniprotkb:D6VXE5|ensemblfungi:YKR085C	intact:EBI-748961|uniprotkb:A8K3Q0|uniprotkb:A8K3U2|uniprotkb:Q6ZQN9|uniprotkb:Q7Z519|uniprotkb:Q8NBS7|uniprotkb:Q8NBY2|uniprotkb:Q9NS19|uniprotkb:Q9NYH3|uniprotkb:Q9UHX9|ensembl:ENSP00000300213	psi-mi:rm20_yeast(display_long)|uniprotkb:MRPL20(gene name)|psi-mi:MRPL20(display_short)|uniprotkb:YKR085C(locus name)|uniprotkb:YKR405(orf name)|uniprotkb:YmL20(gene name synonym)|uniprotkb:Mitochondrial large ribosomal subunit protein mL58(gene name synonym)	psi-mi:ccdb1_human(display_long)|uniprotkb:Grap2 and cyclin-D-interacting protein(gene name synonym)|uniprotkb:Human homolog of Maid(gene name synonym)|uniprotkb:CCNDBP1(gene name)|psi-mi:CCNDBP1(display_short)|uniprotkb:DIP1(gene name synonym)|uniprotkb:GCIP(gene name synonym)|uniprotkb:HHM(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11539418|imex:IM-24995-1794	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013011.1|sgd:S000001793|rcsb pdb:5MRE|rcsb pdb:5MRF|ensemblfungi:YKR085C(gene)|ensemblfungi:YKR085C_mRNA(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR024388|rcsb pdb:3J6B|rcsb pdb:5MRC|dip:DIP-6793N|mint:P22354|sgd:YKR085C(identity)	refseq:NP_036274.3|ensembl:ENSG00000166946(gene)|ensembl:ENST00000300213(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0016604"(nuclear body)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR026907|mint:O95273|rcsb pdb:3AY5|entrezgene/locuslink:23582(identity)	-	crc64:3165663C8C19EC60	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:DkeQ+P79JhbEGKxUK2g8JXvgBSA559292	rogid:Vi9aoFc+Mov6P3X6KGmsTxXqxvM9606	intact-crc:11B60A01CAB2B6F2|rigid:PvXhIWJN9xYnvSkM9aLFQuOQjXQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P23285	uniprotkb:P46379-2	intact:EBI-5448|uniprotkb:D3DL06|ensemblfungi:YHR057C	intact:EBI-10988864|ensembl:ENSP00000211379|ensembl:ENSP00000365143|ensembl:ENSP00000372938|ensembl:ENSP00000372940|ensembl:ENSP00000389121|ensembl:ENSP00000410156|ensembl:ENSP00000412110|ensembl:ENSP00000413698	psi-mi:cypb_yeast(display_long)|uniprotkb:CYP2(gene name synonym)|uniprotkb:YHR057C(locus name)|uniprotkb:CPR2(gene name)|psi-mi:CPR2(display_short)|uniprotkb:CRG(gene name synonym)|uniprotkb:SCC2(gene name synonym)|uniprotkb:Cyclophilin B(gene name synonym)|uniprotkb:Cyclophilin-related protein(gene name synonym)|uniprotkb:Rotamase B(gene name synonym)	psi-mi:p46379-2(display_long)|uniprotkb:BAG6(gene name)|psi-mi:BAG6(display_short)|uniprotkb:BAG family molecular chaperone regulator 6(gene name synonym)|uniprotkb:BAT3(gene name synonym)|uniprotkb:BCL2-associated athanogene 6(gene name synonym)|uniprotkb:G3(gene name synonym)|uniprotkb:HLA-B-associated transcript 3(gene name synonym)|uniprotkb:Protein G3(gene name synonym)|uniprotkb:Protein Scythe(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11539494|imex:IM-24995-1802	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011924.1|sgd:S000001099|dip:DIP-1280N|ensemblfungi:YHR057C(gene)|ensemblfungi:YHR057C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006457"(protein folding)|go:"GO:0016018"(cyclosporin A binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|interpro:IPR020892|interpro:IPR024936|interpro:IPR029000|sgd:YHR057C(identity)	intact:EBI-347552(isoform-parent)|uniprotkb:P46379-2(isoform-parent)|ensembl:ENSG00000096155(gene)|ensembl:ENSG00000204463(gene)|ensembl:ENSG00000229524(gene)|ensembl:ENSG00000233348(gene)|ensembl:ENST00000211379(transcript)|ensembl:ENST00000375976(transcript)|ensembl:ENST00000383446(transcript)|ensembl:ENST00000383448(transcript)|ensembl:ENST00000417144(transcript)|ensembl:ENST00000419847(transcript)|ensembl:ENST00000442479(transcript)|ensembl:ENST00000443182(transcript)|entrezgene/locuslink:7917(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:jKSwBj1KpYZTRNaWOrKxCwC0rAY559292	rogid:7y9hxqfcTmnCBRON6qNoHPCdODY9606	intact-crc:621F0B52F3A4270E|rigid:GJevR6h5GvKTdi1t8sJsrw+dIgE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P23059	uniprotkb:Q9UFD9	intact:EBI-10950|ensemblfungi:YCR020C-A|uniprotkb:D6VR29	intact:EBI-10182375|uniprotkb:Q9UFQ5|uniprotkb:Q8IYP7|uniprotkb:Q9BY94|intact:EBI-28984856|ensembl:ENSP00000483386	psi-mi:naa38_yeast(display_long)|uniprotkb:MAK31(gene name)|psi-mi:MAK31(display_short)|uniprotkb:YCR020C-A(locus name)|uniprotkb:YCR20C-A(orf name)|uniprotkb:L-A virus GAG protein N-acetyltransferase subunit MAK31(gene name synonym)|uniprotkb:Maintenance of killer protein 31(gene name synonym)|uniprotkb:NAA38(gene name synonym)|uniprotkb:N-terminal acetyltransferase C complex subunit MAK31(gene name synonym)	psi-mi:rim3a_human(display_long)|uniprotkb:RIMBP3(gene name)|psi-mi:RIMBP3(display_short)|uniprotkb:KIAA1666(gene name synonym)|uniprotkb:RIMBP3A(gene name synonym)|uniprotkb:RIMS-binding protein 3.1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11539454|imex:IM-24995-1798	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YCR020C-A(gene)|ensemblfungi:YCR020C-A_mRNA(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005688"(U6 snRNP)|go:"GO:0005829"(cytosol)|go:"GO:0006474"(N-terminal protein amino acid acetylation)|go:"GO:0016070"(RNA metabolic process)|go:"GO:0031417"(NatC complex)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071011"(precatalytic spliceosome)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR034110|rcsb pdb:6YGA|rcsb pdb:6YGB|rcsb pdb:6YGC|rcsb pdb:6YGD|refseq:NP_009948.1|sgd:S000000614|mint:P23059|dip:DIP-1429N|sgd:YCR020C-A(identity)	refseq:NP_056487.1|ensembl:ENSP00000483386|ensembl:ENSG00000275793(gene)|ensembl:ENST00000619918(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007286"(spermatid development)|go:"GO:0009566"(fertilization)|go:"GO:0030156"(benzodiazepine receptor binding)|go:"GO:0045202"(synapse)|interpro:IPR001452(Src homology-3)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR035515|interpro:IPR036028|interpro:IPR036116|interpro:IPR040325|rcsb pdb:2EGE|entrezgene/locuslink:85376(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:VUwG0xxj0NeyZKANRYCAgJGuqs8559292	rogid:iw34Gee4nqAH3pqUfCgQ6Jj++AA9606	intact-crc:75DF18580B8760A0|rigid:zNTOeTjSl+BVSEzL3VF/E9J4h2o	false	-	sufficient binding region:838-1639	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9BYV6-2	uniprotkb:P23180	intact:EBI-11522718|ensembl:ENSP00000297348	intact:EBI-24332|uniprotkb:D3DKP4|ensemblfungi:YHL021C	psi-mi:q9byv6-2(display_long)|uniprotkb:TRIM55(gene name)|psi-mi:TRIM55(display_short)|uniprotkb:MURF2(gene name synonym)|uniprotkb:Muscle-specific RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 29(gene name synonym)|uniprotkb:RNF29(gene name synonym)|uniprotkb:p50(isoform synonym)	psi-mi:aim17_yeast(display_long)|uniprotkb:AIM17(gene name)|psi-mi:AIM17(display_short)|uniprotkb:FMP12(gene name synonym)|uniprotkb:Altered inheritance of mitochondria protein 17, mitochondrial(gene name synonym)|uniprotkb:Found in mitochondrial proteome protein 12(gene name synonym)|uniprotkb:YHL021C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11539485|imex:IM-24995-1801	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-2341179(isoform-parent)|uniprotkb:Q9BYV6-2(isoform-parent)|ensembl:ENSG00000147573(gene)|ensembl:ENST00000353317(transcript)|entrezgene/locuslink:84675(identity)	refseq:NP_011842.1|sgd:S000001013|reactome:R-SCE-71262|dip:DIP-4919N|ensemblfungi:YHL021C(gene)|ensemblfungi:YHL021C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0045329"(carnitine biosynthetic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0051213"(dioxygenase activity)|interpro:IPR003819(Taurine catabolism dioxygenase TauD/TfdA)|interpro:IPR042098|sgd:YHL021C(identity)	-	-	crc64:568B17051DB60899	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:9t8UhK+Z1yBqjnQrOqPD76NuXGg9606	rogid:EckG7oFiGF7UJou9Cu2fZCGiUKE559292	intact-crc:F15F02390627CC13|rigid:r5UIlR4ULSzRqRpAZyIMdIwM8e8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UKT9	uniprotkb:P23059	intact:EBI-747204|uniprotkb:Q8WWQ9|uniprotkb:Q8WWR0|uniprotkb:Q8WWR1|uniprotkb:Q8WWR2|uniprotkb:Q8WWR3|uniprotkb:Q8N574|uniprotkb:B4DVV5|uniprotkb:Q69BL6|uniprotkb:Q69BL7|uniprotkb:Q69BL8|uniprotkb:Q69BL9|uniprotkb:Q69BM0|uniprotkb:Q69BM1|uniprotkb:Q69BM2|uniprotkb:Q69BM3|uniprotkb:Q69BM5|ensembl:ENSP00000344544	intact:EBI-10950|ensemblfungi:YCR020C-A|uniprotkb:D6VR29	psi-mi:ikzf3_human(display_long)|uniprotkb:ZNFN1A3(gene name synonym)|uniprotkb:Ikaros family zinc finger protein 3(gene name synonym)|uniprotkb:IKZF3(gene name)|psi-mi:IKZF3(display_short)	psi-mi:naa38_yeast(display_long)|uniprotkb:MAK31(gene name)|psi-mi:MAK31(display_short)|uniprotkb:YCR020C-A(locus name)|uniprotkb:YCR20C-A(orf name)|uniprotkb:L-A virus GAG protein N-acetyltransferase subunit MAK31(gene name synonym)|uniprotkb:Maintenance of killer protein 31(gene name synonym)|uniprotkb:NAA38(gene name synonym)|uniprotkb:N-terminal acetyltransferase C complex subunit MAK31(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11539476|imex:IM-24995-1800	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001271443.1|refseq:NP_001271444.1|refseq:NP_036613.2|refseq:NP_899051.1|refseq:NP_899052.1|refseq:NP_899053.1|refseq:NP_899054.1|refseq:NP_899055.1|refseq:NP_001271445.1|refseq:NP_001244337.1|refseq:NP_001244338.1|refseq:NP_001244339.1|refseq:NP_001244340.1|refseq:NP_001244341.1|refseq:NP_001244342.1|refseq:NP_001244343.1|ensembl:ENSG00000161405(gene)|ensembl:ENST00000346872(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007498"(mesoderm development)|go:"GO:0009617"(response to bacterium)|go:"GO:0030888"(regulation of B cell proliferation)|go:"GO:0042113"(B cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045577"(regulation of B cell differentiation)|go:"GO:0045619"(regulation of lymphocyte differentiation)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|go:"GO:0046872"(metal ion binding)|dip:DIP-56975N|entrezgene/locuslink:22806(identity)	ensemblfungi:YCR020C-A(gene)|ensemblfungi:YCR020C-A_mRNA(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005688"(U6 snRNP)|go:"GO:0005829"(cytosol)|go:"GO:0006474"(N-terminal protein amino acid acetylation)|go:"GO:0016070"(RNA metabolic process)|go:"GO:0031417"(NatC complex)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071011"(precatalytic spliceosome)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR034110|rcsb pdb:6YGA|rcsb pdb:6YGB|rcsb pdb:6YGC|rcsb pdb:6YGD|refseq:NP_009948.1|sgd:S000000614|mint:P23059|dip:DIP-1429N|sgd:YCR020C-A(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:2Kp6LefSLfK5VIiE6DmQusFIfMY9606	rogid:VUwG0xxj0NeyZKANRYCAgJGuqs8559292	intact-crc:12FAB6206E17DE4A|rigid:7/DvT/1dtf1pZQqfsZaJOCyhnUI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P23059	uniprotkb:Q9UJV3-2	intact:EBI-10950|ensemblfungi:YCR020C-A|uniprotkb:D6VR29	intact:EBI-10172526|ensembl:ENSP00000413976	psi-mi:naa38_yeast(display_long)|uniprotkb:MAK31(gene name)|psi-mi:MAK31(display_short)|uniprotkb:YCR020C-A(locus name)|uniprotkb:YCR20C-A(orf name)|uniprotkb:L-A virus GAG protein N-acetyltransferase subunit MAK31(gene name synonym)|uniprotkb:Maintenance of killer protein 31(gene name synonym)|uniprotkb:NAA38(gene name synonym)|uniprotkb:N-terminal acetyltransferase C complex subunit MAK31(gene name synonym)	psi-mi:q9ujv3-2(display_long)|uniprotkb:RING-type E3 ubiquitin transferase MID2(gene name synonym)|uniprotkb:FXY2(gene name synonym)|uniprotkb:Midin-2(gene name synonym)|uniprotkb:Midline defect 2(gene name synonym)|uniprotkb:Midline-2(gene name synonym)|uniprotkb:RING finger protein 60(gene name synonym)|uniprotkb:RNF60(gene name synonym)|uniprotkb:TRIM1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 1(gene name synonym)|uniprotkb:MID2(gene name)|psi-mi:MID2(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11539465|imex:IM-24995-1799	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YCR020C-A(gene)|ensemblfungi:YCR020C-A_mRNA(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005688"(U6 snRNP)|go:"GO:0005829"(cytosol)|go:"GO:0006474"(N-terminal protein amino acid acetylation)|go:"GO:0016070"(RNA metabolic process)|go:"GO:0031417"(NatC complex)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071011"(precatalytic spliceosome)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR034110|rcsb pdb:6YGA|rcsb pdb:6YGB|rcsb pdb:6YGC|rcsb pdb:6YGD|refseq:NP_009948.1|sgd:S000000614|mint:P23059|dip:DIP-1429N|sgd:YCR020C-A(identity)	intact:EBI-751983(isoform-parent)|uniprotkb:Q9UJV3-2(isoform-parent)|ensembl:ENSG00000080561(gene)|ensembl:ENST00000443968(transcript)|entrezgene/locuslink:11043(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:VUwG0xxj0NeyZKANRYCAgJGuqs8559292	rogid:/FJ+V2H7SaWon7caUWkEkmHFVxQ9606	intact-crc:CBDFD71203C666D2|rigid:UHUc4T8tYrgIDj6hGi2K0oJGCYk	false	-	sufficient binding region:21-705	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P23285	uniprotkb:Q9Y2W7	intact:EBI-5448|uniprotkb:D3DL06|ensemblfungi:YHR057C	intact:EBI-751501|uniprotkb:Q53TJ5|uniprotkb:Q96T40|uniprotkb:Q9UJ84|uniprotkb:Q9UJ85|uniprotkb:Q3YAC3|uniprotkb:Q3YAC4|uniprotkb:H7BY46|ensembl:ENSP00000295225	psi-mi:cypb_yeast(display_long)|uniprotkb:CYP2(gene name synonym)|uniprotkb:YHR057C(locus name)|uniprotkb:CPR2(gene name)|psi-mi:CPR2(display_short)|uniprotkb:CRG(gene name synonym)|uniprotkb:SCC2(gene name synonym)|uniprotkb:Cyclophilin B(gene name synonym)|uniprotkb:Cyclophilin-related protein(gene name synonym)|uniprotkb:Rotamase B(gene name synonym)	psi-mi:csen_human(display_long)|uniprotkb:Kv channel-interacting protein 3(gene name synonym)|uniprotkb:A-type potassium channel modulatory protein 3(gene name synonym)|uniprotkb:DRE-antagonist modulator(gene name synonym)|uniprotkb:KCNIP3(gene name)|psi-mi:KCNIP3(display_short)|uniprotkb:DREAM(gene name synonym)|uniprotkb:KCHIP3(gene name synonym)|uniprotkb:CSEN(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11539503|imex:IM-24995-1803	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011924.1|sgd:S000001099|dip:DIP-1280N|ensemblfungi:YHR057C(gene)|ensemblfungi:YHR057C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006457"(protein folding)|go:"GO:0016018"(cyclosporin A binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|interpro:IPR020892|interpro:IPR024936|interpro:IPR029000|sgd:YHR057C(identity)	refseq:NP_001030086.1|refseq:NP_038462.1|ensembl:ENSG00000115041(gene)|ensembl:ENST00000295225(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005244"(voltage-gated ion channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0030425"(dendrite)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0043679"(axon terminus)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:1901379"(regulation of potassium ion transmembrane transport)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR028846|rcsb pdb:2E6W|reactome:R-HSA-5576894|entrezgene/locuslink:30818(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:jKSwBj1KpYZTRNaWOrKxCwC0rAY559292	rogid:Mqp4XdEur4uc6jY9dGsn8CHLE4w9606	intact-crc:98316A490E3AFA33|rigid:aQbFCfB0uPIea3j+XVISVUl8XIw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q5JR59-3	uniprotkb:P23293	intact:EBI-11522433|ensembl:ENSP00000370186	intact:EBI-17078|ensemblfungi:YPR161C|uniprotkb:D6W4G2	psi-mi:q5jr59-3(display_long)|uniprotkb:MTUS2(gene name)|psi-mi:MTUS2(display_short)|uniprotkb:CAZIP(gene name synonym)|uniprotkb:Cardiac zipper protein(gene name synonym)|uniprotkb:KIAA0774(gene name synonym)|uniprotkb:Microtubule plus-end tracking protein TIP150(gene name synonym)|uniprotkb:TIP150(gene name synonym)	psi-mi:bur1_yeast(display_long)|uniprotkb:SGV1(gene name)|psi-mi:SGV1(display_short)|uniprotkb:BUR1(gene name synonym)|uniprotkb:YPR161C(locus name)|uniprotkb:P9584.8(orf name)|uniprotkb:Bypass UAS requirement protein 1(gene name synonym)|uniprotkb:Suppressor of GPA1-Vall50 mutation protein 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11539523|imex:IM-24995-1805	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000132938(gene)|ensembl:ENST00000380808(transcript)|intact:EBI-742948(isoform-parent)|uniprotkb:Q5JR59-3(isoform-parent)|entrezgene/locuslink:23281(identity)	interpro:IPR011009(Protein kinase-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-SCE-674695|reactome:R-SCE-6796648|reactome:R-SCE-6807505|reactome:R-SCE-75955|reactome:R-SCE-9018519|refseq:NP_015487.1|sgd:S000006365|ensemblfungi:YPR161C(gene)|ensemblfungi:YPR161C_mRNA(transcript)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0030332"(cyclin binding)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|dip:DIP-5916N|mint:P23293|sgd:YPR161C(identity)	-	isoform-comment:No experimental confirmation available.	crc64:CC9034A4B10A510E	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:npId9tC7VoLN/jteoBiRbSYChPs9606	rogid:yPWc2VNSXjSxoSgzeiu7Jy5S1C0559292	intact-crc:50EA2E8A2E574EC2|rigid:/q/RGhuOXkmYRC6xFcgGn2RsXgQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P23968	uniprotkb:Q8N6L0	intact:EBI-20293|uniprotkb:D3DKX3|ensemblfungi:YHR026W	intact:EBI-749265|uniprotkb:Q96MC3|ensembl:ENSP00000404220	psi-mi:vato_yeast(display_long)|uniprotkb:VMA16(gene name)|psi-mi:VMA16(display_short)|uniprotkb:PPA1(gene name synonym)|uniprotkb:YHR026W(locus name)|uniprotkb:Vacuolar proton pump c'' subunit(gene name synonym)|uniprotkb:V-ATPase 22 kDa proteolipid subunit(gene name synonym)	psi-mi:kash5_human(display_long)|uniprotkb:KASH5(gene name)|psi-mi:KASH5(display_short)|uniprotkb:CCDC155(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 155(gene name synonym)|uniprotkb:KASH domain-containing protein 5(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11539532|imex:IM-24995-1806	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011891.1|sgd:S000001068|rcsb pdb:6O7W|rcsb pdb:6O7X|rcsb pdb:6PE4|rcsb pdb:6PE5|reactome:R-SCE-1222556|reactome:R-SCE-77387|reactome:R-SCE-917977|reactome:R-SCE-9639288|ensemblfungi:YHR026W(gene)|ensemblfungi:YHR026W_mRNA(transcript)|go:"GO:0000220"(vacuolar proton-transporting V-type ATPase, V0 domain)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0008553"(P-type proton-exporting transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016471"(vacuolar proton-transporting V-type ATPase complex)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR000245(ATPase, V0 complex, proteolipid subunit C,)|interpro:IPR002379(ATPase, F0/V0 complex, subunit C)|interpro:IPR035921|rcsb pdb:5TJ5|rcsb pdb:5VOX|rcsb pdb:5VOY|rcsb pdb:5VOZ|rcsb pdb:6C6L|rcsb pdb:6M0R|rcsb pdb:6M0S|rcsb pdb:6O7T|rcsb pdb:6O7U|rcsb pdb:6O7V|dip:DIP-4054N|mint:P23968|sgd:YHR026W(identity)	refseq:NP_653289.3|ensembl:ENSG00000161609(gene)|ensembl:ENST00000447857(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034397"(telomere localization)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051225"(spindle assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0090172"(microtubule cytoskeleton organization involved in homologous chromosome segregation)|go:"GO:0090220"(chromosome localization to nuclear envelope involved in homologous chromosome segregation)|go:"GO:0090619"(meiotic spindle pole)|interpro:IPR011992(EF-Hand type)|interpro:IPR028168|interpro:IPR028170|interpro:IPR039508|mint:Q8N6L0|rcsb pdb:6R2I|rcsb pdb:6WMF|entrezgene/locuslink:147872(identity)	-	crc64:033FF5A516B97F8B	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:pQMMMGsUAtBoa6IF8yVU2t+odQQ559292	rogid:Wl9L7AcvDHCZuKjYLn8QgGIbZTc9606	intact-crc:88B087D8BE7BC075|rigid:6kULBrDc7RKOSwU40SNKrsukouQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96BA8	uniprotkb:P23968	intact:EBI-6942903|ensembl:ENSP00000481956|intact:MINT-268046|intact:MINT-8162577|uniprotkb:Q8N2D5|uniprotkb:Q96CP0	intact:EBI-20293|uniprotkb:D3DKX3|ensemblfungi:YHR026W	psi-mi:cr3l1_human(display_long)|uniprotkb:CREB3L1(gene name)|psi-mi:CREB3L1(display_short)|uniprotkb:OASIS(gene name synonym)|uniprotkb:PSEC0238(orf name)|uniprotkb:Old astrocyte specifically-induced substance(gene name synonym)	psi-mi:vato_yeast(display_long)|uniprotkb:VMA16(gene name)|psi-mi:VMA16(display_short)|uniprotkb:PPA1(gene name synonym)|uniprotkb:YHR026W(locus name)|uniprotkb:Vacuolar proton pump c'' subunit(gene name synonym)|uniprotkb:V-ATPase 22 kDa proteolipid subunit(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11539541|imex:IM-24995-1807	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157613(gene)|ensembl:ENST00000621158(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0070278"(extracellular matrix constituent secretion)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029805|mint:Q96BA8|reactome:R-HSA-8874211|refseq:NP_443086.1|entrezgene/locuslink:90993(identity)	refseq:NP_011891.1|sgd:S000001068|rcsb pdb:6O7W|rcsb pdb:6O7X|rcsb pdb:6PE4|rcsb pdb:6PE5|reactome:R-SCE-1222556|reactome:R-SCE-77387|reactome:R-SCE-917977|reactome:R-SCE-9639288|ensemblfungi:YHR026W(gene)|ensemblfungi:YHR026W_mRNA(transcript)|go:"GO:0000220"(vacuolar proton-transporting V-type ATPase, V0 domain)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0008553"(P-type proton-exporting transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016471"(vacuolar proton-transporting V-type ATPase complex)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR000245(ATPase, V0 complex, proteolipid subunit C,)|interpro:IPR002379(ATPase, F0/V0 complex, subunit C)|interpro:IPR035921|rcsb pdb:5TJ5|rcsb pdb:5VOX|rcsb pdb:5VOY|rcsb pdb:5VOZ|rcsb pdb:6C6L|rcsb pdb:6M0R|rcsb pdb:6M0S|rcsb pdb:6O7T|rcsb pdb:6O7U|rcsb pdb:6O7V|dip:DIP-4054N|mint:P23968|sgd:YHR026W(identity)	-	comment:mint|function:"Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE"	crc64:033FF5A516B97F8B	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:sMWUFmBeBBCO+T0Y2CuB/un1lBg9606	rogid:pQMMMGsUAtBoa6IF8yVU2t+odQQ559292	intact-crc:21981A45A363BDB1|rigid:yZXLin542GrbPE4nOM51K4bgRXA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q08379	uniprotkb:P23293	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	intact:EBI-17078|ensemblfungi:YPR161C|uniprotkb:D6W4G2	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:bur1_yeast(display_long)|uniprotkb:SGV1(gene name)|psi-mi:SGV1(display_short)|uniprotkb:BUR1(gene name synonym)|uniprotkb:YPR161C(locus name)|uniprotkb:P9584.8(orf name)|uniprotkb:Bypass UAS requirement protein 1(gene name synonym)|uniprotkb:Suppressor of GPA1-Vall50 mutation protein 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11539512|imex:IM-24995-1804	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N|entrezgene/locuslink:2801(identity)	interpro:IPR011009(Protein kinase-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-SCE-674695|reactome:R-SCE-6796648|reactome:R-SCE-6807505|reactome:R-SCE-75955|reactome:R-SCE-9018519|refseq:NP_015487.1|sgd:S000006365|ensemblfungi:YPR161C(gene)|ensemblfungi:YPR161C_mRNA(transcript)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0030332"(cyclin binding)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|dip:DIP-5916N|mint:P23293|sgd:YPR161C(identity)	-	-	crc64:CC9034A4B10A510E	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2017/05/26	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	rogid:yPWc2VNSXjSxoSgzeiu7Jy5S1C0559292	intact-crc:8807A041802C7F0B|rigid:c8aT+hdlQkCrd4qPTq7qtHXpwp4	false	sufficient binding region:383-1002	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9BTE3-2	uniprotkb:P24279	intact:EBI-9384556|ensembl:ENSP00000358073	intact:EBI-10541|ensemblfungi:YEL032W|uniprotkb:D3DLL7	psi-mi:q9bte3-2(display_long)|uniprotkb:MCMBP(gene name)|psi-mi:MCMBP(display_short)|uniprotkb:C10orf119(gene name synonym)	psi-mi:mcm3_yeast(display_long)|uniprotkb:MCM3(gene name)|psi-mi:MCM3(display_short)|uniprotkb:YEL032W(locus name)|uniprotkb:SYGP-ORF23(orf name)|uniprotkb:Minichromosome maintenance protein 3(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11539551|imex:IM-24995-1808	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-749378(isoform-parent)|uniprotkb:Q9BTE3-2(isoform-parent)|ensembl:ENSG00000197771(gene)|ensembl:ENST00000369077(transcript)|entrezgene/locuslink:79892(identity)	refseq:NP_010882.1|sgd:S000000758|go:"GO:0005524"(ATP binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006348"|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0042555"(MCM complex)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902975"(mitotic DNA replication initiation)|go:"GO:1904931"(MCM complex binding)|interpro:IPR001208(MCM)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR008046(MCM protein 3)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|rcsb pdb:3JA8|rcsb pdb:3JC5|rcsb pdb:3JC6|rcsb pdb:3JC7|rcsb pdb:5BK4|rcsb pdb:5U8S|rcsb pdb:5U8T|rcsb pdb:5V8F|rcsb pdb:6EYC|rcsb pdb:6F0L|rcsb pdb:6HV9|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6RQC|rcsb pdb:6SKL|rcsb pdb:6SKO|rcsb pdb:6U0M|rcsb pdb:6WGC|rcsb pdb:6WGF|rcsb pdb:6WGG|rcsb pdb:6WGI|reactome:R-SCE-68949|reactome:R-SCE-68962|reactome:R-SCE-69052|rcsb pdb:5XF8|ensemblfungi:YEL032W(gene)|ensemblfungi:YEL032W_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|mint:P24279|dip:DIP-2407N|sgd:YEL032W(identity)	-	-	crc64:43DD4DACAF4456DC	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:nJOq6jis1maK+M/X0TcR44HlxRw9606	rogid:OsFbdaTeE1vPQObriGt5M6mTPzk559292	intact-crc:B3DC5839FEDC93D5|rigid:vu2Hl8RYLaSrtUaj8zIr7gqfUhw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q6RW13-2	uniprotkb:P24280	intact:EBI-11522760|ensembl:ENSP00000365816	intact:EBI-16535|uniprotkb:D6VZQ3|ensemblfungi:YMR079W	psi-mi:q6rw13-2(display_long)|uniprotkb:AGTRAP(gene name)|psi-mi:AGTRAP(display_short)|uniprotkb:AT1 receptor-associated protein(gene name synonym)|uniprotkb:ATRAP(gene name synonym)	psi-mi:sec14_yeast(display_long)|uniprotkb:SEC14(gene name)|psi-mi:SEC14(display_short)|uniprotkb:Phosphatidylinositol/phosphatidylcholine transfer protein(gene name synonym)|uniprotkb:PIT1(gene name synonym)|uniprotkb:YM9582.04(orf name)|uniprotkb:YMR079W(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11539560|imex:IM-24995-1809	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000177674(gene)|ensembl:ENST00000376629(transcript)|intact:EBI-741181(isoform-parent)|uniprotkb:Q6RW13-2(isoform-parent)|entrezgene/locuslink:57085(identity)	refseq:NP_013796.1|sgd:S000004684|ensemblfungi:YMR079W(gene)|ensemblfungi:YMR079W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0008525"(phosphatidylcholine transporter activity)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0008526"(phosphatidylinositol transfer activity)|go:"GO:0015914"(phospholipid transport)|go:"GO:0030437"(ascospore formation)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0046488"(phosphatidylinositol metabolic process)|go:"GO:0048194"(Golgi vesicle budding)|go:"GO:1901352"(negative regulation of phosphatidylglycerol biosynthetic process)|go:"GO:2001246"(negative regulation of phosphatidylcholine biosynthetic process)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR011074(Phosphatidylinositol transfer protein-like, N-terminal)|interpro:IPR036273|interpro:IPR036865|rcsb pdb:1AUA|rcsb pdb:6F0E|dip:DIP-1610N|mint:P24280|sgd:YMR079W(identity)	-	-	crc64:CCB69404A8A0963B	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:PNzVis/8puQZBJ562gCqZKc078s9606	rogid:6KY0fOn92xmZkZBq10NHRCWtd7w559292	intact-crc:7153B4E9284CEBB7|rigid:Om2ejsdhmZcM+TfO/PN828HwyqI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96DZ9-2	uniprotkb:P24280	intact:EBI-11522780|ensembl:ENSP00000352270|ensembl:ENSP00000497215	intact:EBI-16535|uniprotkb:D6VZQ3|ensemblfungi:YMR079W	psi-mi:q96dz9-2(display_long)|uniprotkb:CMTM5(gene name)|psi-mi:CMTM5(display_short)|uniprotkb:CKLFSF5(gene name synonym)|uniprotkb:Chemokine-like factor superfamily member 5(gene name synonym)	psi-mi:sec14_yeast(display_long)|uniprotkb:SEC14(gene name)|psi-mi:SEC14(display_short)|uniprotkb:Phosphatidylinositol/phosphatidylcholine transfer protein(gene name synonym)|uniprotkb:PIT1(gene name synonym)|uniprotkb:YM9582.04(orf name)|uniprotkb:YMR079W(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11539569|imex:IM-24995-1810	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000166091(gene)|ensembl:ENST00000359320(transcript)|ensembl:ENST00000649278(transcript)|intact:EBI-2548702(isoform-parent)|uniprotkb:Q96DZ9-2(isoform-parent)|entrezgene/locuslink:116173(identity)	refseq:NP_013796.1|sgd:S000004684|ensemblfungi:YMR079W(gene)|ensemblfungi:YMR079W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0008525"(phosphatidylcholine transporter activity)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0008526"(phosphatidylinositol transfer activity)|go:"GO:0015914"(phospholipid transport)|go:"GO:0030437"(ascospore formation)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0046488"(phosphatidylinositol metabolic process)|go:"GO:0048194"(Golgi vesicle budding)|go:"GO:1901352"(negative regulation of phosphatidylglycerol biosynthetic process)|go:"GO:2001246"(negative regulation of phosphatidylcholine biosynthetic process)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR011074(Phosphatidylinositol transfer protein-like, N-terminal)|interpro:IPR036273|interpro:IPR036865|rcsb pdb:1AUA|rcsb pdb:6F0E|dip:DIP-1610N|mint:P24280|sgd:YMR079W(identity)	-	-	crc64:CCB69404A8A0963B	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:2TJ7rZKQNb5hH5gz9i+ujOEOIOg9606	rogid:6KY0fOn92xmZkZBq10NHRCWtd7w559292	intact-crc:14D343EA0DF56DFB|rigid:L/SnJTuS/SdJO7xn0y/aL4LubYI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9H972-2	uniprotkb:P25044	intact:EBI-11524174|ensembl:ENSP00000341353	intact:EBI-14183|ensemblfungi:YDL230W|uniprotkb:D6VRC6	psi-mi:q9h972-2(display_long)|uniprotkb:C14orf93(gene name)|psi-mi:C14orf93(display_short)	psi-mi:ptp1_yeast(display_long)|uniprotkb:Protein-tyrosine phosphatase 1(gene name synonym)|uniprotkb:PTP1(gene name)|psi-mi:PTP1(display_short)|uniprotkb:YDL230W(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11539578|imex:IM-24995-1811	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-10329620(isoform-parent)|ensembl:ENSG00000100802(gene)|ensembl:ENST00000341470(transcript)|uniprotkb:Q9H972-2(isoform-parent)|entrezgene/locuslink:60686(identity)	refseq:NP_010051.1|sgd:S000002389|ensemblfungi:YDL230W(gene)|ensemblfungi:YDL230W_mRNA(transcript)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007124"(pseudohyphal growth)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR016277(Non-receptor tyrosine-protein phosphatase type 1, yeast)|interpro:IPR029021|go:"GO:0005737"(cytoplasm)|dip:DIP-2765N|reactome:R-SCE-6798695|sgd:YDL230W(identity)	-	isoform-comment:No experimental confirmation available.	crc64:15F71E50694BE562	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:78CwgvNc8HhvQM4urISJ8VU88BU9606	rogid:uQd7Homoz5Z834hLaSgQssol+EE559292	intact-crc:C5B46A2428402DC3|rigid:BlfdJ2WU+yBQv0fitvOxz4ATEXg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P25299	uniprotkb:Q7Z3B4	intact:EBI-15640|uniprotkb:D6VU95|ensemblfungi:YGL044C	intact:EBI-741048|uniprotkb:Q96EA7|uniprotkb:Q9NVL5|uniprotkb:Q9P0I1|uniprotkb:B2RCK7|intact:EBI-10966427|uniprotkb:B4DT35|ensembl:ENSP00000264883	psi-mi:rna15_yeast(display_long)|uniprotkb:YGL044C(locus name)|uniprotkb:RNA15(gene name)|psi-mi:RNA15(display_short)	psi-mi:nup54_human(display_long)|uniprotkb:54 kDa nucleoporin(gene name synonym)|uniprotkb:NUP54(gene name)|psi-mi:NUP54(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11539587|imex:IM-24995-1812	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011471.1|sgd:S000003012|ensemblfungi:YGL044C(gene)|ensemblfungi:YGL044C_mRNA(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0005849"(mRNA cleavage factor complex)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0072423"(response to DNA damage checkpoint signaling)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR026896|interpro:IPR035979|interpro:IPR038192|rcsb pdb:2KM8|rcsb pdb:2L9B|rcsb pdb:2X1A|rcsb pdb:2X1B|rcsb pdb:2X1F|dip:DIP-1489N|mint:P25299|sgd:YGL044C(identity)	refseq:NP_059122.2|refseq:NP_001265532.1|ensembl:ENSG00000138750(gene)|ensembl:ENST00000264883(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0006605"(protein targeting)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036228"(protein localization to nuclear inner membrane)|go:"GO:0042306"(regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051028"(mRNA transport)|interpro:IPR024864|interpro:IPR025712|interpro:IPR040985|mint:Q7Z3B4|rcsb pdb:4JNU|rcsb pdb:4JNV|rcsb pdb:4JO7|rcsb pdb:4JO9|rcsb pdb:5IJN|rcsb pdb:5IJO|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|entrezgene/locuslink:53371(identity)	-	crc64:10053B8648A71ECB	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:TqfxsTHAh9CPJJ6Q7uH6kz988hk559292	rogid:/X2b8J20uRh86bEeCc1tJSRuaIM9606	intact-crc:78B58C3ED67A1FEB|rigid:DPrDjqDiTFRoLirTjKgYNRaYX3Q	false	-	sufficient binding region:1-493	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P25299	uniprotkb:Q9HD26-2	intact:EBI-15640|uniprotkb:D6VU95|ensemblfungi:YGL044C	intact:EBI-11102276|ensembl:ENSP00000052569	psi-mi:rna15_yeast(display_long)|uniprotkb:YGL044C(locus name)|uniprotkb:RNA15(gene name)|psi-mi:RNA15(display_short)	psi-mi:q9hd26-2(display_long)|uniprotkb:GOPC(gene name)|psi-mi:GOPC(display_short)|uniprotkb:CAL(gene name synonym)|uniprotkb:CFTR-associated ligand(gene name synonym)|uniprotkb:FIG(gene name synonym)|uniprotkb:Fused in glioblastoma(gene name synonym)|uniprotkb:PDZ protein interacting specifically with TC10(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11539598|imex:IM-24995-1813	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011471.1|sgd:S000003012|ensemblfungi:YGL044C(gene)|ensemblfungi:YGL044C_mRNA(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0005849"(mRNA cleavage factor complex)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0072423"(response to DNA damage checkpoint signaling)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR026896|interpro:IPR035979|interpro:IPR038192|rcsb pdb:2KM8|rcsb pdb:2L9B|rcsb pdb:2X1A|rcsb pdb:2X1B|rcsb pdb:2X1F|dip:DIP-1489N|mint:P25299|sgd:YGL044C(identity)	ensembl:ENSG00000047932(gene)|ensembl:ENST00000052569(transcript)|intact:EBI-349832(isoform-parent)|uniprotkb:Q9HD26-2(isoform-parent)|entrezgene/locuslink:57120(identity)	-	crc64:10053B8648A71ECB	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:TqfxsTHAh9CPJJ6Q7uH6kz988hk559292	rogid:QoEGY54FfmwTrpGVMQN9ASGPgVI9606	intact-crc:0B4550CB96E1C32E|rigid:uWGqexURRYxTTx+kiSeq1kdSbkc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P25299	uniprotkb:Q9UJ83	intact:EBI-15640|uniprotkb:D6VU95|ensemblfungi:YGL044C	intact:EBI-746580|uniprotkb:Q9BV42|uniprotkb:Q9P0A2|ensembl:ENSP00000323811|uniprotkb:E9PEN4|uniprotkb:B4DWI1|uniprotkb:B4DXI5	psi-mi:rna15_yeast(display_long)|uniprotkb:YGL044C(locus name)|uniprotkb:RNA15(gene name)|psi-mi:RNA15(display_short)	psi-mi:hacl1_human(display_long)|uniprotkb:2-hydroxyphytanoyl-CoA lyase(gene name synonym)|uniprotkb:Phytanoyl-CoA 2-hydroxylase 2(gene name synonym)|uniprotkb:HACL1(gene name)|psi-mi:HACL1(display_short)|uniprotkb:HPCL2(gene name synonym)|uniprotkb:HSPC279(orf name)|uniprotkb:HPCL(gene name synonym)|uniprotkb:PHYH2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11539607|imex:IM-24995-1814	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011471.1|sgd:S000003012|ensemblfungi:YGL044C(gene)|ensemblfungi:YGL044C_mRNA(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0005849"(mRNA cleavage factor complex)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0072423"(response to DNA damage checkpoint signaling)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR026896|interpro:IPR035979|interpro:IPR038192|rcsb pdb:2KM8|rcsb pdb:2L9B|rcsb pdb:2X1A|rcsb pdb:2X1B|rcsb pdb:2X1F|dip:DIP-1489N|mint:P25299|sgd:YGL044C(identity)	refseq:NP_001271344.1|refseq:NP_036392.2|ensembl:ENSG00000131373(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005777"(peroxisome)|ensembl:ENST00000321169(transcript)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006625"(protein targeting to peroxisome)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0016830"(carbon-carbon lyase activity)|go:"GO:0030976"(thiamine pyrophosphate binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0097089"(methyl-branched fatty acid metabolic process)|go:"GO:0106360"(2-hydroxy-3-methylhexadecanoyl-CoA lyase activity)|go:"GO:0106376"(2-hydroxyphytanoyl-CoA lyase activity)|go:"GO:1903512"(phytanic acid metabolic process)|interpro:IPR011766(Thiamine pyrophosphate enzyme, C-terminal TPP-binding)|interpro:IPR012000(Thiamine pyrophosphate enzyme, central region)|interpro:IPR012001(Thiamine pyrophosphate enzyme, N-terminal TPP binding region)|interpro:IPR029035|interpro:IPR029061|reactome:R-HSA-389599|reactome:R-HSA-9033241|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001561"(fatty acid alpha-oxidation)|refseq:NP_001271342.1|refseq:NP_001271345.1|entrezgene/locuslink:26061(identity)	-	crc64:10053B8648A71ECB	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:TqfxsTHAh9CPJJ6Q7uH6kz988hk559292	rogid:030QpE5/e+3ZEuyUaK+RM3w8x4A9606	intact-crc:4645CA19B1B74E5B|rigid:Ufyq0B2HZmr8lq+Ii+gGlqTRJ1E	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O15217	uniprotkb:P25335	intact:EBI-752440|uniprotkb:Q5T7Q8|uniprotkb:Q9BX18|uniprotkb:Q9H414|uniprotkb:B2RD15|uniprotkb:Q6P4G1|ensembl:ENSP00000359998|ensembl:ENSP00000360002	intact:EBI-2442|uniprotkb:D6VVW0|ensemblfungi:YIR029W	psi-mi:gsta4_human(display_long)|uniprotkb:Glutathione S-transferase A4-4(gene name synonym)|uniprotkb:GST class-alpha member 4(gene name synonym)|uniprotkb:GSTA4(gene name)|psi-mi:GSTA4(display_short)	psi-mi:allc_yeast(display_long)|uniprotkb:DAL2(gene name)|psi-mi:DAL2(display_short)|uniprotkb:ALC1(gene name synonym)|uniprotkb:Allantoate amidinohydrolase(gene name synonym)|uniprotkb:YIR029W(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11539616|imex:IM-24995-1815	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001503.1|refseq:XP_005249092.1|ensembl:ENSG00000170899(gene)|ensembl:ENST00000370959(transcript)|ensembl:ENST00000370963(transcript)|go:"GO:0004364"(glutathione transferase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0006805"(xenobiotic metabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|interpro:IPR003080(Glutathione S-transferase, alpha class)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR036249|interpro:IPR036282|interpro:IPR040079|rcsb pdb:1GUL|rcsb pdb:1GUM|rcsb pdb:3IK7|reactome:R-HSA-156590|entrezgene/locuslink:2941(identity)	refseq:NP_012295.1|sgd:S000001468|interpro:IPR005164(Allantoicase)|interpro:IPR015908(Allantoicase region)|interpro:IPR008979(Galactose-binding like)|rcsb pdb:1O59|rcsb pdb:1SG3|ensemblfungi:YIR029W(gene)|ensemblfungi:YIR029W_mRNA(transcript)|go:"GO:0000256"(allantoin catabolic process)|go:"GO:0004037"(allantoicase activity)|go:"GO:0006144"(purine nucleobase metabolic process)|sgd:YIR029W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:9yVcqmJL64S0kxOW5RJWbOJ25bo9606	rogid:N4TpitQzuAZuemg9Jk458EUQUWc559292	intact-crc:3C8C9303058509F3|rigid:HcrN/v7EspNcIkRwbk4OjqYnRgk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9BW62	uniprotkb:P25337	intact:EBI-743591|uniprotkb:A8K5X4|ensembl:ENSP00000369989|ensembl:ENSP00000369991	intact:EBI-547|ensemblfungi:YCR063W|uniprotkb:D6VR67	psi-mi:katl1_human(display_long)|uniprotkb:p60 katanin-like 1(gene name synonym)|uniprotkb:KATNAL1(gene name)|psi-mi:KATNAL1(display_short)	psi-mi:bud31_yeast(display_long)|uniprotkb:BUD31(gene name)|psi-mi:BUD31(display_short)|uniprotkb:Bud site selection protein 31(gene name synonym)|uniprotkb:CWC14(gene name synonym)|uniprotkb:Complexed with CEF1 protein 14(gene name synonym)|uniprotkb:YCR63W(orf name)|uniprotkb:YCR903(orf name)|uniprotkb:YCR063W(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11539625|imex:IM-24995-1816	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001014402.1|refseq:NP_115492.1|refseq:XP_005266631.1|ensembl:ENSG00000102781(gene)|ensembl:ENST00000380615(transcript)|ensembl:ENST00000380617(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005874"(microtubule)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008017"(microtubule binding)|go:"GO:0008568"(microtubule-severing ATPase activity)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016853"(isomerase activity)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0042802"(identical protein binding)|go:"GO:0051013"(microtubule severing)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR027417|interpro:IPR028594|interpro:IPR028596|interpro:IPR041569|rcsb pdb:6B5C|entrezgene/locuslink:84056(identity)	refseq:NP_009990.1|sgd:S000000659|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005686"(U2 snRNP)|interpro:IPR001748(G10 protein)|interpro:IPR018230|rcsb pdb:2MY1|ensemblfungi:YCR063W(gene)|ensemblfungi:YCR063W_mRNA(transcript)|go:"GO:0000282"(cellular bud site selection)|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|dip:DIP-1180N|mint:P25337|sgd:YCR063W(identity)	-	-	crc64:70A8B15F8DA6F85D	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Usi4KXsvZnNfMOGuWVSz4mfrTaE9606	rogid:DImrf7jgUrSuQtfiOvBeJr5Cl/w559292	intact-crc:75AE508251CEC572|rigid:gvpInP+Nf6YG6/dZY+d6nRz8z3k	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9H9H4	uniprotkb:P25343	intact:EBI-4400866|intact:EBI-28975719|ensembl:ENSP00000267202	intact:EBI-14490|uniprotkb:D6VR18|ensemblfungi:YCR009C	psi-mi:vp37b_human(display_long)|uniprotkb:VPS37B(gene name)|psi-mi:VPS37B(display_short)|uniprotkb:ESCRT-I complex subunit VPS37B(gene name synonym)	psi-mi:rv161_yeast(display_long)|uniprotkb:RVS161(gene name)|psi-mi:RVS161(display_short)|uniprotkb:END6(gene name synonym)|uniprotkb:SPE161(gene name synonym)|uniprotkb:YCR009C(locus name)|uniprotkb:YCR9C(orf name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11539663|imex:IM-24995-1820	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000267202|refseq:NP_078943.1|ensembl:ENSG00000139722(gene)|ensembl:ENST00000267202(transcript)|go:"GO:0000813"(ESCRT I complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0010008"(endosome membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0030496"(midbody)|go:"GO:0031902"(late endosome membrane)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1902188"(obsolete positive regulation of viral release from host cell)|go:"GO:1903774"(positive regulation of viral budding via host ESCRT complex)|interpro:IPR009851(Modifier of rudimentary, Modr)|interpro:IPR029012|interpro:IPR037202|mint:Q9H9H4|rcsb pdb:6VME|reactome:R-HSA-162588|reactome:R-HSA-174490|reactome:R-HSA-917729|reactome:R-HSA-9610379|reactome:R-HSA-9615710|entrezgene/locuslink:79720(identity)	ensemblfungi:YCR009C(gene)|ensemblfungi:YCR009C_mRNA(transcript)|go:"GO:0000747"(conjugation with cellular fusion)|go:"GO:0005829"(cytosol)|go:"GO:0005937"(mating projection)|go:"GO:0006897"(endocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030479"(actin cortical patch)|go:"GO:0031097"(medial cortex)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0042594"(response to starvation)|go:"GO:0043332"(mating projection tip)|go:"GO:0045121"(membrane raft)|go:"GO:0051666"(actin cortical patch localization)|go:"GO:0060988"(lipid tube assembly)|go:"GO:0097320"(plasma membrane tubulation)|go:"GO:1990528"(Rvs161p-Rvs167p complex)|interpro:IPR004148(BAR)|interpro:IPR027267|go:"GO:0006970"(response to osmotic stress)|interpro:IPR037429|refseq:NP_009935.1|sgd:S000000602|mint:P25343|dip:DIP-1601N|sgd:YCR009C(identity)	-	-	crc64:B35EA00E0C900E2D	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:dj398+zsegXf+gk9OiSeZAVlmqk9606	rogid:IdjO8RS5vcYMeGxuoPoa/5e7QJQ559292	intact-crc:C6F092E92B5ACA0F|rigid:pgwHh6rLZ+gz+I8+RrqpD7S9KyI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q969F0	uniprotkb:P25353	intact:EBI-743099|ensembl:ENSP00000359375	intact:EBI-3691762|uniprotkb:D6VR36|uniprotkb:Q8NIL9|ensemblfungi:YCR026C	psi-mi:fate1_human(display_long)|uniprotkb:Tumor antigen BJ-HCC-2(gene name synonym)|uniprotkb:Cancer/testis antigen 43(gene name synonym)|uniprotkb:FATE1(gene name)|psi-mi:FATE1(display_short)|uniprotkb:FATE(gene name synonym)	psi-mi:npp1_yeast(display_long)|uniprotkb:NPP1(gene name)|psi-mi:NPP1(display_short)|uniprotkb:YCR26C(orf name)|uniprotkb:YCR246(orf name)|uniprotkb:YCR026C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11539672|imex:IM-24995-1821	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_149076.1|ensembl:ENSG00000147378(gene)|ensembl:ENST00000370350(transcript)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|go:"GO:0051562"(negative regulation of mitochondrial calcium ion concentration)|interpro:IPR039153|interpro:IPR039433|mint:Q969F0|entrezgene/locuslink:89885(identity)	refseq:NP_009955.2|sgd:S000000621|interpro:IPR017850(Alkaline-phosphatase-like, core domain)|interpro:IPR002591(Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase)|reactome:R-SCE-1660662|reactome:R-SCE-6814848|ensemblfungi:YCR026C(gene)|ensemblfungi:YCR026C_mRNA(transcript)|go:"GO:0004528"(phosphodiesterase I activity)|go:"GO:0009141"(nucleoside triphosphate metabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016036"(cellular response to phosphate starvation)|go:"GO:0017111"(nucleoside-triphosphatase activity)|go:"GO:0035529"(NADH pyrophosphatase activity)|go:"GO:0036218"(dTTP diphosphatase activity)|go:"GO:0047429"(nucleoside-triphosphate diphosphatase activity)|reactome:R-SCE-196843|reactome:R-SCE-6798695|sgd:YCR026C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Nm1N6lO92MHr5rIKC007oouF5RE9606	rogid:eudbgXN3Y6QR2ebTYl+l1JoNuG0559292	intact-crc:667AE9E49728BE96|rigid:iOSqFRP5udaWXmqwEmtaFlHj9jM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P25343	uniprotkb:P14136	intact:EBI-14490|uniprotkb:D6VR18|ensemblfungi:YCR009C	intact:EBI-744302|uniprotkb:Q53H98|uniprotkb:Q5D055|uniprotkb:Q6ZQS3|uniprotkb:Q7Z5J6|uniprotkb:Q7Z5J7|uniprotkb:Q96KS4|uniprotkb:Q96P18|uniprotkb:Q9UFD0|uniprotkb:B2RD44|uniprotkb:D3DX59|intact:EBI-3909365|uniprotkb:E9PAX3|ensembl:ENSP00000466598|uniprotkb:A7REI1	psi-mi:rv161_yeast(display_long)|uniprotkb:RVS161(gene name)|psi-mi:RVS161(display_short)|uniprotkb:END6(gene name synonym)|uniprotkb:SPE161(gene name synonym)|uniprotkb:YCR009C(locus name)|uniprotkb:YCR9C(orf name)	psi-mi:gfap_human(display_long)|uniprotkb:GFAP(gene name)|psi-mi:GFAP(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11539645|imex:IM-24995-1818	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YCR009C(gene)|ensemblfungi:YCR009C_mRNA(transcript)|go:"GO:0000747"(conjugation with cellular fusion)|go:"GO:0005829"(cytosol)|go:"GO:0005937"(mating projection)|go:"GO:0006897"(endocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030479"(actin cortical patch)|go:"GO:0031097"(medial cortex)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0042594"(response to starvation)|go:"GO:0043332"(mating projection tip)|go:"GO:0045121"(membrane raft)|go:"GO:0051666"(actin cortical patch localization)|go:"GO:0060988"(lipid tube assembly)|go:"GO:0097320"(plasma membrane tubulation)|go:"GO:1990528"(Rvs161p-Rvs167p complex)|interpro:IPR004148(BAR)|interpro:IPR027267|go:"GO:0006970"(response to osmotic stress)|interpro:IPR037429|refseq:NP_009935.1|sgd:S000000602|mint:P25343|dip:DIP-1601N|sgd:YCR009C(identity)	refseq:NP_001124491.1|refseq:NP_001229305.1|refseq:NP_002046.1|ensembl:ENSG00000131095(gene)|ensembl:ENST00000588735(transcript)|go:"GO:0005178"(integrin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0009611"(response to wounding)|go:"GO:0010467"(gene expression)|go:"GO:0010625"(positive regulation of Schwann cell proliferation)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0014002"(astrocyte development)|go:"GO:0019900"(kinase binding)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0031102"(neuron projection regeneration)|go:"GO:0042802"(identical protein binding)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0044297"(cell body)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0051580"(regulation of neurotransmitter uptake)|go:"GO:0060020"(Bergmann glial cell differentiation)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0070779"(D-aspartate import across plasma membrane)|go:"GO:0097450"(astrocyte end-foot)|go:"GO:0098574"(cytoplasmic side of lysosomal membrane)|go:"GO:1904714"(regulation of chaperone-mediated autophagy)|interpro:IPR006821(Intermediate filament, DNA-binding region)|interpro:IPR018039|interpro:IPR027701|interpro:IPR039008|mint:P14136|rcsb pdb:6A9P|reactome:R-HSA-1251985|reactome:R-HSA-9613829|entrezgene/locuslink:2670(identity)	-	crc64:B35EA00E0C900E2D	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:IdjO8RS5vcYMeGxuoPoa/5e7QJQ559292	rogid:Pz4JW0WjMjBYILTDSX9jUmMqWhg9606	intact-crc:162332969B5A9371|rigid:WHUjOicWVQnQ5I/yFWGjBsSZtUQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O15156-2	uniprotkb:P25343	intact:EBI-11522250|ensembl:ENSP00000406286	intact:EBI-14490|uniprotkb:D6VR18|ensemblfungi:YCR009C	psi-mi:o15156-2(display_long)|uniprotkb:ZBTB7B(gene name)|psi-mi:ZBTB7B(display_short)|uniprotkb:Krueppel-related zinc finger protein cKrox(gene name synonym)|uniprotkb:T-helper-inducing POZ/Krueppel-like factor(gene name synonym)|uniprotkb:ZBTB15(gene name synonym)|uniprotkb:ZFP67(gene name synonym)|uniprotkb:ZNF857B(gene name synonym)|uniprotkb:Zinc finger and BTB domain-containing protein 15(gene name synonym)|uniprotkb:Zinc finger protein 67 homolog(gene name synonym)|uniprotkb:Zinc finger protein 857B(gene name synonym)|uniprotkb:Zinc finger protein Th-POK(gene name synonym)	psi-mi:rv161_yeast(display_long)|uniprotkb:RVS161(gene name)|psi-mi:RVS161(display_short)|uniprotkb:END6(gene name synonym)|uniprotkb:SPE161(gene name synonym)|uniprotkb:YCR009C(locus name)|uniprotkb:YCR9C(orf name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11539634|imex:IM-24995-1817	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-740434(isoform-parent)|ensembl:ENSG00000160685(gene)|ensembl:ENST00000417934(transcript)|uniprotkb:O15156-2(isoform-parent)|entrezgene/locuslink:51043(identity)	ensemblfungi:YCR009C(gene)|ensemblfungi:YCR009C_mRNA(transcript)|go:"GO:0000747"(conjugation with cellular fusion)|go:"GO:0005829"(cytosol)|go:"GO:0005937"(mating projection)|go:"GO:0006897"(endocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030479"(actin cortical patch)|go:"GO:0031097"(medial cortex)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0042594"(response to starvation)|go:"GO:0043332"(mating projection tip)|go:"GO:0045121"(membrane raft)|go:"GO:0051666"(actin cortical patch localization)|go:"GO:0060988"(lipid tube assembly)|go:"GO:0097320"(plasma membrane tubulation)|go:"GO:1990528"(Rvs161p-Rvs167p complex)|interpro:IPR004148(BAR)|interpro:IPR027267|go:"GO:0006970"(response to osmotic stress)|interpro:IPR037429|refseq:NP_009935.1|sgd:S000000602|mint:P25343|dip:DIP-1601N|sgd:YCR009C(identity)	-	isoform-comment:No experimental confirmation available.	crc64:B35EA00E0C900E2D	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:41NEFYyprTXI+fOHVFh78TPKF289606	rogid:IdjO8RS5vcYMeGxuoPoa/5e7QJQ559292	intact-crc:084AFC33CA205B6C|rigid:gM6N97nvBxr3+9i2/GfwyjGQenQ	false	sufficient binding region:35-573	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q15427	uniprotkb:P25343	intact:EBI-348469|ensembl:ENSP00000271628|intact:EBI-1047735|uniprotkb:Q5SZ63	intact:EBI-14490|uniprotkb:D6VR18|ensemblfungi:YCR009C	psi-mi:sf3b4_human(display_long)|uniprotkb:SF3B4(gene name)|psi-mi:SF3B4(display_short)|uniprotkb:SAP49(gene name synonym)|uniprotkb:Spliceosome-associated protein 49(gene name synonym)|uniprotkb:Pre-mRNA-splicing factor SF3b 49 kDa subunit(gene name synonym)	psi-mi:rv161_yeast(display_long)|uniprotkb:RVS161(gene name)|psi-mi:RVS161(display_short)|uniprotkb:END6(gene name synonym)|uniprotkb:SPE161(gene name synonym)|uniprotkb:YCR009C(locus name)|uniprotkb:YCR9C(orf name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11539654|imex:IM-24995-1819	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005841.1|ensembl:ENSG00000143368(gene)|ensembl:ENST00000271628(transcript)|rcsb pdb:6QX9|rcsb pdb:6Y53|rcsb pdb:6Y5Q|rcsb pdb:7ABG|rcsb pdb:7ABH|rcsb pdb:7ABI|rcsb pdb:7DVQ|reactome:R-HSA-72163|reactome:R-HSA-72165|rcsb pdb:6AHD|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:1990935"(splicing factor binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034158|go:"GO:0000375"(RNA splicing, via transesterification reactions)|interpro:IPR034159|interpro:IPR035979|mint:Q15427|rcsb pdb:1X5T|rcsb pdb:5GVQ|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|entrezgene/locuslink:10262(identity)	ensemblfungi:YCR009C(gene)|ensemblfungi:YCR009C_mRNA(transcript)|go:"GO:0000747"(conjugation with cellular fusion)|go:"GO:0005829"(cytosol)|go:"GO:0005937"(mating projection)|go:"GO:0006897"(endocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030479"(actin cortical patch)|go:"GO:0031097"(medial cortex)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0042594"(response to starvation)|go:"GO:0043332"(mating projection tip)|go:"GO:0045121"(membrane raft)|go:"GO:0051666"(actin cortical patch localization)|go:"GO:0060988"(lipid tube assembly)|go:"GO:0097320"(plasma membrane tubulation)|go:"GO:1990528"(Rvs161p-Rvs167p complex)|interpro:IPR004148(BAR)|interpro:IPR027267|go:"GO:0006970"(response to osmotic stress)|interpro:IPR037429|refseq:NP_009935.1|sgd:S000000602|mint:P25343|dip:DIP-1601N|sgd:YCR009C(identity)	-	-	crc64:B35EA00E0C900E2D	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Jgy6WmBFKkphpZLLte2GgsagUVI9606	rogid:IdjO8RS5vcYMeGxuoPoa/5e7QJQ559292	intact-crc:E9336E3566F00EBB|rigid:bknMPZefJNeyCajFqg2U1zUynFk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P63279	uniprotkb:P25354	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	intact:EBI-21848|uniprotkb:Q70DH1|uniprotkb:Q70DH4|uniprotkb:Q70DH6|uniprotkb:D6VR16|ensemblfungi:YCR007C	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:ycp7_yeast(display_long)|uniprotkb:YCR045(orf name)|uniprotkb:YCR7C(orf name)|uniprotkb:YCR007C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11539681|imex:IM-24995-1822	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N|entrezgene/locuslink:7329(identity)	refseq:NP_009933.1|sgd:S000000600|dip:DIP-4043N|ensemblfungi:YCR007C(gene)|ensemblfungi:YCR007C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|interpro:IPR001142(Yeast membrane protein DUP)|sgd:YCR007C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	rogid:5AYWvsKbIkyI0AaAP811MKfdVXI559292	intact-crc:653882051FBDC2B8|rigid:R1WRsBaowNpKKdpBR0jtU7mUOMU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P25372	uniprotkb:Q08379	intact:EBI-19616|uniprotkb:D6VR84|ensemblfungi:YCR083W	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	psi-mi:trx3_yeast(display_long)|uniprotkb:TRX3(gene name)|psi-mi:TRX3(display_short)|uniprotkb:YCR83W(orf name)|uniprotkb:YCR083W(locus name)	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11539699|imex:IM-24995-1824	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR036249|refseq:NP_010006.1|sgd:S000000679|interpro:IPR017937|interpro:IPR013766(Thioredoxin domain)|rcsb pdb:2OE0|rcsb pdb:2OE1|rcsb pdb:2OE3|ensemblfungi:YCR083W(gene)|ensemblfungi:YCR083W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0015036"(disulfide oxidoreductase activity)|go:"GO:0034599"(cellular response to oxidative stress)|rcsb pdb:5YKW|sgd:YCR083W(identity)	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N|entrezgene/locuslink:2801(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2017/05/26	rogid:g0xjGf9GvJRl8iv2qoT5tOs7jXI559292	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	intact-crc:ECE241244657EF32|rigid:nwv71IkwKmL4x3nV92ZKFMB1U+U	false	-	sufficient binding region:383-1002	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P25372	uniprotkb:O14641	intact:EBI-19616|uniprotkb:D6VR84|ensemblfungi:YCR083W	intact:EBI-740850|ensembl:ENSP00000005340|uniprotkb:Q53XM0|uniprotkb:D3DTN3	psi-mi:trx3_yeast(display_long)|uniprotkb:TRX3(gene name)|psi-mi:TRX3(display_short)|uniprotkb:YCR83W(orf name)|uniprotkb:YCR083W(locus name)	psi-mi:dvl2_human(display_long)|uniprotkb:DSH homolog 2(gene name synonym)|uniprotkb:DVL2(gene name)|psi-mi:DVL2(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11539710|imex:IM-24995-1825	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR036249|refseq:NP_010006.1|sgd:S000000679|interpro:IPR017937|interpro:IPR013766(Thioredoxin domain)|rcsb pdb:2OE0|rcsb pdb:2OE1|rcsb pdb:2OE3|ensemblfungi:YCR083W(gene)|ensemblfungi:YCR083W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0015036"(disulfide oxidoreductase activity)|go:"GO:0034599"(cellular response to oxidative stress)|rcsb pdb:5YKW|sgd:YCR083W(identity)	refseq:NP_004413.1|ensembl:ENSG00000004975(gene)|ensembl:ENST00000005340(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005109"(frizzled binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0007507"(heart development)|go:"GO:0016235"(aggresome)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044340"(canonical Wnt signaling pathway involved in regulation of cell proliferation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0150012"(positive regulation of neuron projection arborization)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008341(Dishevelled-2 region)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:O14641|rcsb pdb:2REY|rcsb pdb:3CBX|rcsb pdb:3CBY|rcsb pdb:3CBZ|rcsb pdb:3CC0|rcsb pdb:4WIP|rcsb pdb:5LNP|rcsb pdb:5SUY|rcsb pdb:5SUZ|rcsb pdb:6IW3|rcsb pdb:6JCK|reactome:R-HSA-201681|reactome:R-HSA-201688|reactome:R-HSA-2028269|reactome:R-HSA-4086400|reactome:R-HSA-4608870|reactome:R-HSA-4641258|reactome:R-HSA-4641262|reactome:R-HSA-5099900|reactome:R-HSA-5368598|reactome:R-HSA-5663220|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9673324|ensembl:ENSP00000005340|dip:DIP-34433N|entrezgene/locuslink:1856(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:g0xjGf9GvJRl8iv2qoT5tOs7jXI559292	rogid:2Vdc8oRnT4Mz/j+EXQXrL3AszOc9606	intact-crc:655FF5023B890209|rigid:qW2yYituG07tnqilIn18HK/zMxA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P25372	intact:EBI-11524292	intact:EBI-19616|uniprotkb:D6VR84|ensemblfungi:YCR083W	-	psi-mi:trx3_yeast(display_long)|uniprotkb:TRX3(gene name)|psi-mi:TRX3(display_short)|uniprotkb:YCR83W(orf name)|uniprotkb:YCR083W(locus name)	psi-mi:trip6(display_short)|psi-mi:EBI-11524292(display_long)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11539690|imex:IM-24995-1823	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR036249|refseq:NP_010006.1|sgd:S000000679|interpro:IPR017937|interpro:IPR013766(Thioredoxin domain)|rcsb pdb:2OE0|rcsb pdb:2OE1|rcsb pdb:2OE3|ensemblfungi:YCR083W(gene)|ensemblfungi:YCR083W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0015036"(disulfide oxidoreductase activity)|go:"GO:0034599"(cellular response to oxidative stress)|rcsb pdb:5YKW|sgd:YCR083W(identity)	entrezgene/locuslink:7205(identity)	-	-	no-uniprot-update:	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:g0xjGf9GvJRl8iv2qoT5tOs7jXI559292	rogid:S6W5lkNauGhNejln9bTVoqZjNL49606	intact-crc:3E92D6AF30264A6D|rigid:bwExTIDGQGpNGL73rMESgXrHyc0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P25372	uniprotkb:O95073-2	intact:EBI-19616|uniprotkb:D6VR84|ensemblfungi:YCR083W	intact:EBI-10696047	psi-mi:trx3_yeast(display_long)|uniprotkb:TRX3(gene name)|psi-mi:TRX3(display_short)|uniprotkb:YCR83W(orf name)|uniprotkb:YCR083W(locus name)	psi-mi:o95073-2(display_long)|uniprotkb:FSBP(gene name)|psi-mi:FSBP(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11539730|imex:IM-24995-1827	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR036249|refseq:NP_010006.1|sgd:S000000679|interpro:IPR017937|interpro:IPR013766(Thioredoxin domain)|rcsb pdb:2OE0|rcsb pdb:2OE1|rcsb pdb:2OE3|ensemblfungi:YCR083W(gene)|ensemblfungi:YCR083W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0015036"(disulfide oxidoreductase activity)|go:"GO:0034599"(cellular response to oxidative stress)|rcsb pdb:5YKW|sgd:YCR083W(identity)	intact:EBI-1059030(isoform-parent)|uniprotkb:O95073-2(isoform-parent)|entrezgene/locuslink:25788(identity)	-	-	isoform-comment:No experimental confirmation available.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:g0xjGf9GvJRl8iv2qoT5tOs7jXI559292	rogid:j4ktleFZa7rAjRFENAKAGdAd+Fs9606	intact-crc:7AA7D05ED0827051|rigid:pVxgkpSkBuFL5XF5oz/yAWRx/4Y	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P25372	uniprotkb:O43379	intact:EBI-19616|uniprotkb:D6VR84|ensemblfungi:YCR083W	intact:EBI-714790|uniprotkb:Q63HP9|uniprotkb:Q659D7|uniprotkb:Q8NBF7|uniprotkb:Q96AD9|intact:EBI-2563293|ensembl:ENSP00000270301	psi-mi:trx3_yeast(display_long)|uniprotkb:TRX3(gene name)|psi-mi:TRX3(display_short)|uniprotkb:YCR83W(orf name)|uniprotkb:YCR083W(locus name)	psi-mi:wdr62_human(display_long)|uniprotkb:WDR62(gene name)|psi-mi:WDR62(display_short)|uniprotkb:C19orf14(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11539719|imex:IM-24995-1826	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR036249|refseq:NP_010006.1|sgd:S000000679|interpro:IPR017937|interpro:IPR013766(Thioredoxin domain)|rcsb pdb:2OE0|rcsb pdb:2OE1|rcsb pdb:2OE3|ensemblfungi:YCR083W(gene)|ensemblfungi:YCR083W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0015036"(disulfide oxidoreductase activity)|go:"GO:0034599"(cellular response to oxidative stress)|rcsb pdb:5YKW|sgd:YCR083W(identity)	go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007099"(centriole replication)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0022008"(neurogenesis)|go:"GO:0034451"(centriolar satellite)|interpro:IPR001680(WD40 repeat)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR024977|interpro:IPR036322|mint:O43379|go:"GO:0005813"(centrosome)|ensembl:ENSG00000075702(gene)|ensembl:ENST00000270301(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|refseq:NP_001077430.1|refseq:NP_775907.4|refseq:XP_016882154.1|dip:DIP-56792N|entrezgene/locuslink:284403(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:g0xjGf9GvJRl8iv2qoT5tOs7jXI559292	rogid:bKUivd80luQPFZHsU9mDdwyGwi89606	intact-crc:04681A146F62D182|rigid:ItU3uRHsL/1Qfpgrmgytvc+ufWg	false	-	sufficient binding region:889-1518	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P25372	uniprotkb:P01100	intact:EBI-19616|uniprotkb:D6VR84|ensemblfungi:YCR083W	intact:EBI-852851|uniprotkb:P18849|uniprotkb:A8K4E2|uniprotkb:B4DQ65|ensembl:ENSP00000306245	psi-mi:trx3_yeast(display_long)|uniprotkb:TRX3(gene name)|psi-mi:TRX3(display_short)|uniprotkb:YCR83W(orf name)|uniprotkb:YCR083W(locus name)	psi-mi:fos_human(display_long)|uniprotkb:Cellular oncogene fos(gene name synonym)|uniprotkb:G0/G1 switch regulatory protein 7(gene name synonym)|uniprotkb:FOS(gene name)|psi-mi:FOS(display_short)|uniprotkb:G0S7(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11539739|imex:IM-24995-1828	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR036249|refseq:NP_010006.1|sgd:S000000679|interpro:IPR017937|interpro:IPR013766(Thioredoxin domain)|rcsb pdb:2OE0|rcsb pdb:2OE1|rcsb pdb:2OE3|ensemblfungi:YCR083W(gene)|ensemblfungi:YCR083W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0015036"(disulfide oxidoreductase activity)|go:"GO:0034599"(cellular response to oxidative stress)|rcsb pdb:5YKW|sgd:YCR083W(identity)	refseq:NP_005243.1|dip:DIP-1047N|ensembl:ENSG00000170345(gene)|ensembl:ENST00000303562(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001661"(conditioned taste aversion)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006306"(DNA methylation)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006954"(inflammatory response)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007399"(nervous system development)|go:"GO:0007565"(female pregnancy)|go:"GO:0007568"(aging)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009409"(response to cold)|go:"GO:0009416"(response to light stimulus)|go:"GO:0009629"(response to gravity)|go:"GO:0009636"(response to toxic substance)|go:"GO:0016020"(membrane)|go:"GO:0030431"(sleep)|go:"GO:0031668"(cellular response to extracellular stimulus)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032570"(response to progesterone)|go:"GO:0032870"(cellular response to hormone stimulus)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034097"(response to cytokine)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035902"(response to immobilization stress)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0035976"(transcription factor AP-1 complex)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045672"(positive regulation of osteoclast differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051412"(response to corticosterone)|go:"GO:0051591"(response to cAMP)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000837(Fos transforming protein)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029816|rcsb pdb:1A02|rcsb pdb:1FOS|rcsb pdb:1S9K|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2871796|reactome:R-HSA-450341|reactome:R-HSA-6785807|reactome:R-HSA-6796648|reactome:R-HSA-9018519|reactome:R-HSA-9031628|reactome:R-HSA-9634638|entrezgene/locuslink:2353(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:g0xjGf9GvJRl8iv2qoT5tOs7jXI559292	rogid:R09jzTKeAyzIQYTQAsps2UWFyFE9606	intact-crc:5C324A6AA09F1A69|rigid:I9lOBxbMyqcagDUwjOiVWfRerZc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P25372	uniprotkb:Q12800	intact:EBI-19616|uniprotkb:D6VR84|ensemblfungi:YCR083W	intact:EBI-717422|uniprotkb:Q12801|uniprotkb:Q9UD77|uniprotkb:A8K5E9|uniprotkb:Q9UD75|ensembl:ENSP00000257915	psi-mi:trx3_yeast(display_long)|uniprotkb:TRX3(gene name)|psi-mi:TRX3(display_short)|uniprotkb:YCR83W(orf name)|uniprotkb:YCR083W(locus name)	psi-mi:tfcp2_human(display_long)|uniprotkb:Transcription factor LSF(gene name synonym)|uniprotkb:SAA3 enhancer factor(gene name synonym)|uniprotkb:TFCP2(gene name)|psi-mi:TFCP2(display_short)|uniprotkb:LSF(gene name synonym)|uniprotkb:SEF(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11539766|imex:IM-24995-1831	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR036249|refseq:NP_010006.1|sgd:S000000679|interpro:IPR017937|interpro:IPR013766(Thioredoxin domain)|rcsb pdb:2OE0|rcsb pdb:2OE1|rcsb pdb:2OE3|ensemblfungi:YCR083W(gene)|ensemblfungi:YCR083W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0015036"(disulfide oxidoreductase activity)|go:"GO:0034599"(cellular response to oxidative stress)|rcsb pdb:5YKW|sgd:YCR083W(identity)	refseq:NP_001166923.1|refseq:NP_001166924.1|refseq:NP_005644.2|ensembl:ENSG00000135457(gene)|ensembl:ENST00000257915(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR007604(CP2 transcription factor)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR037599|interpro:IPR041418|mint:Q12800|entrezgene/locuslink:7024(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:g0xjGf9GvJRl8iv2qoT5tOs7jXI559292	rogid:M7mQ08NDYxuawmUEKRgjSdIr+Og9606	intact-crc:8A529937CC77E390|rigid:32XPbIfd3r2o9unzkwhEZF9w+Kk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P25372	uniprotkb:P14373	intact:EBI-19616|uniprotkb:D6VR84|ensemblfungi:YCR083W	intact:EBI-719493|uniprotkb:A2BE15|uniprotkb:Q5RJA8|uniprotkb:Q5ST26|uniprotkb:Q6LA73|uniprotkb:Q6NXR9|uniprotkb:Q9BZY6|uniprotkb:Q9UJL3|ensembl:ENSP00000383555|ensembl:ENSP00000392787|ensembl:ENSP00000405229|ensembl:ENSP00000414793|ensembl:ENSP00000366404	psi-mi:trx3_yeast(display_long)|uniprotkb:TRX3(gene name)|psi-mi:TRX3(display_short)|uniprotkb:YCR83W(orf name)|uniprotkb:YCR083W(locus name)	psi-mi:tri27_human(display_long)|uniprotkb:TRIM27(gene name)|psi-mi:TRIM27(display_short)|uniprotkb:RNF76(gene name synonym)|uniprotkb:RFP(gene name synonym)|uniprotkb:Ret finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 27(gene name synonym)|uniprotkb:RING finger protein 76(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM27(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11539748|imex:IM-24995-1829	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR036249|refseq:NP_010006.1|sgd:S000000679|interpro:IPR017937|interpro:IPR013766(Thioredoxin domain)|rcsb pdb:2OE0|rcsb pdb:2OE1|rcsb pdb:2OE3|ensemblfungi:YCR083W(gene)|ensemblfungi:YCR083W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0015036"(disulfide oxidoreductase activity)|go:"GO:0034599"(cellular response to oxidative stress)|rcsb pdb:5YKW|sgd:YCR083W(identity)	refseq:NP_006501.1|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0090281"(negative regulation of calcium ion import)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR020457|interpro:IPR035791|interpro:IPR043136|mint:P14373|reactome:R-HSA-3232142|reactome:R-HSA-9635465|reactome:R-HSA-8948751|ensembl:ENSG00000204713(gene)|ensembl:ENSG00000215641(gene)|ensembl:ENSG00000229006(gene)|ensembl:ENSG00000234495(gene)|ensembl:ENSG00000237071(gene)|ensembl:ENST00000377199(transcript)|ensembl:ENST00000400720(transcript)|ensembl:ENST00000431123(transcript)|ensembl:ENST00000435528(transcript)|ensembl:ENST00000437160(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001650"(fibrillar center)|go:"GO:0002820"(negative regulation of adaptive immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|entrezgene/locuslink:5987(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:g0xjGf9GvJRl8iv2qoT5tOs7jXI559292	rogid:dsfH5OUghD8KSaTz1SFw9OYVTK49606	intact-crc:4D6D97760E7BC401|rigid:or242VUGNkFq7Yqk1gx8Af1pjBQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P25372	uniprotkb:P19012	intact:EBI-19616|uniprotkb:D6VR84|ensemblfungi:YCR083W	intact:EBI-739566|uniprotkb:Q53XV8|uniprotkb:Q9BUG4|uniprotkb:B3KQY1|uniprotkb:B3KRA2|uniprotkb:E0CX14|ensembl:ENSP00000254043|ensembl:ENSP00000377546	psi-mi:trx3_yeast(display_long)|uniprotkb:TRX3(gene name)|psi-mi:TRX3(display_short)|uniprotkb:YCR83W(orf name)|uniprotkb:YCR083W(locus name)	psi-mi:k1c15_human(display_long)|uniprotkb:KRT15(gene name)|psi-mi:KRT15(display_short)|uniprotkb:KRTB(gene name synonym)|uniprotkb:Cytokeratin-15(gene name synonym)|uniprotkb:Keratin-15(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11539757|imex:IM-24995-1830	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR036249|refseq:NP_010006.1|sgd:S000000679|interpro:IPR017937|interpro:IPR013766(Thioredoxin domain)|rcsb pdb:2OE0|rcsb pdb:2OE1|rcsb pdb:2OE3|ensemblfungi:YCR083W(gene)|ensemblfungi:YCR083W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0015036"(disulfide oxidoreductase activity)|go:"GO:0034599"(cellular response to oxidative stress)|rcsb pdb:5YKW|sgd:YCR083W(identity)	refseq:NP_002266.2|ensembl:ENSG00000171346(gene)|ensembl:ENST00000254043(transcript)|ensembl:ENST00000393976(transcript)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0008544"(epidermis development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097110"(scaffold protein binding)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR039008|mint:P19012|reactome:R-HSA-6805567|reactome:R-HSA-6809371|entrezgene/locuslink:3866(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:g0xjGf9GvJRl8iv2qoT5tOs7jXI559292	rogid:WrZQBYQvrWcfrR5ojWXrXp6spPE9606	intact-crc:AFA2B255A7C786CF|rigid:rhj9ZjA14YeiQhCoKba8ZQBdWXI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P25372	uniprotkb:Q13643	intact:EBI-19616|uniprotkb:D6VR84|ensemblfungi:YCR083W	intact:EBI-741101|ensembl:ENSP00000362107|uniprotkb:Q6I9T0|uniprotkb:Q9BVA2|uniprotkb:D3DPT6	psi-mi:trx3_yeast(display_long)|uniprotkb:TRX3(gene name)|psi-mi:TRX3(display_short)|uniprotkb:YCR83W(orf name)|uniprotkb:YCR083W(locus name)	psi-mi:fhl3_human(display_long)|uniprotkb:FHL3(gene name)|psi-mi:FHL3(display_short)|uniprotkb:SLIM2(gene name synonym)|uniprotkb:Skeletal muscle LIM-protein 2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11539784|imex:IM-24995-1833	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR036249|refseq:NP_010006.1|sgd:S000000679|interpro:IPR017937|interpro:IPR013766(Thioredoxin domain)|rcsb pdb:2OE0|rcsb pdb:2OE1|rcsb pdb:2OE3|ensemblfungi:YCR083W(gene)|ensemblfungi:YCR083W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0015036"(disulfide oxidoreductase activity)|go:"GO:0034599"(cellular response to oxidative stress)|rcsb pdb:5YKW|sgd:YCR083W(identity)	refseq:NP_004459.2|ensembl:ENSG00000183386(gene)|ensembl:ENST00000373016(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005925"(focal adhesion)|go:"GO:0007517"(muscle organ development)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0046872"(metal ion binding)|interpro:IPR001781(Zinc finger, LIM-type)|mint:Q13643|rcsb pdb:1WYH|rcsb pdb:2CUQ|rcsb pdb:2EHE|interpro:IPR037987|refseq:NP_001230807.1|dip:DIP-42030N|entrezgene/locuslink:2275(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:g0xjGf9GvJRl8iv2qoT5tOs7jXI559292	rogid:RAo+b/VgFSnHSbgR+zXuxJvypxM9606	intact-crc:70FEEDDE70AB3F1B|rigid:YeK0bnB8BkoATG8To/38UsoOSAI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P25372	uniprotkb:Q13422-7	intact:EBI-19616|uniprotkb:D6VR84|ensemblfungi:YCR083W	intact:EBI-11522367|ensembl:ENSP00000352123|ensembl:ENSP00000413025	psi-mi:trx3_yeast(display_long)|uniprotkb:TRX3(gene name)|psi-mi:TRX3(display_short)|uniprotkb:YCR83W(orf name)|uniprotkb:YCR083W(locus name)	psi-mi:q13422-7(display_long)|uniprotkb:IKZF1(gene name)|psi-mi:IKZF1(display_short)|uniprotkb:IK1(gene name synonym)|uniprotkb:IKAROS(gene name synonym)|uniprotkb:Ikaros family zinc finger protein 1(gene name synonym)|uniprotkb:LYF1(gene name synonym)|uniprotkb:Lymphoid transcription factor LyF-1(gene name synonym)|uniprotkb:ZNFN1A1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11539775|imex:IM-24995-1832	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR036249|refseq:NP_010006.1|sgd:S000000679|interpro:IPR017937|interpro:IPR013766(Thioredoxin domain)|rcsb pdb:2OE0|rcsb pdb:2OE1|rcsb pdb:2OE3|ensemblfungi:YCR083W(gene)|ensemblfungi:YCR083W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0015036"(disulfide oxidoreductase activity)|go:"GO:0034599"(cellular response to oxidative stress)|rcsb pdb:5YKW|sgd:YCR083W(identity)	intact:EBI-745305(isoform-parent)|ensembl:ENSG00000185811(gene)|ensembl:ENST00000359197(transcript)|ensembl:ENST00000439701(transcript)|uniprotkb:Q13422-7(isoform-parent)|entrezgene/locuslink:10320(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:g0xjGf9GvJRl8iv2qoT5tOs7jXI559292	rogid:ou/ovXYoMneBNVp4pj38VxenfyY9606	intact-crc:B5DB0FC4D7BAE36D|rigid:hAtZFbHwprHaYM4ZMSZuJSh4SWk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8IYA8	uniprotkb:P25372	intact:EBI-8638439|intact:EBI-28969497|ensembl:ENSP00000296449|ensembl:ENSP00000391788|ensembl:ENSP00000407837|uniprotkb:C9JJL0|uniprotkb:Q96LP7|intact:MINT-8162095|uniprotkb:Q05DG9	intact:EBI-19616|uniprotkb:D6VR84|ensemblfungi:YCR083W	psi-mi:iho1_human(display_long)|uniprotkb:IHO1(gene name)|psi-mi:IHO1(display_short)|uniprotkb:CCDC36(gene name synonym)|uniprotkb:Cancer/testis antigen 74(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 36(gene name synonym)	psi-mi:trx3_yeast(display_long)|uniprotkb:TRX3(gene name)|psi-mi:TRX3(display_short)|uniprotkb:YCR83W(orf name)|uniprotkb:YCR083W(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11539823|imex:IM-24995-1837	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000296449|ensembl:ENST00000366429|ensembl:ENSP00000403700|ensembl:ENSP00000391788|ensembl:ENSP00000407837|ensembl:ENSG00000173421(gene)|ensembl:ENST00000296449(transcript)|ensembl:ENST00000438782(transcript)|ensembl:ENST00000452691(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0006310"(DNA recombination)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0042138"(meiotic DNA double-strand break formation)|go:"GO:0048477"(oogenesis)|go:"GO:0060629"(regulation of homologous chromosome segregation)|interpro:IPR031529|mint:Q8IYA8|refseq:XP_011531974.1|refseq:XP_011531975.1|refseq:NP_001128669.1|refseq:NP_835467.2|refseq:XP_006713187.1|entrezgene/locuslink:339834(identity)	interpro:IPR036249|refseq:NP_010006.1|sgd:S000000679|interpro:IPR017937|interpro:IPR013766(Thioredoxin domain)|rcsb pdb:2OE0|rcsb pdb:2OE1|rcsb pdb:2OE3|ensemblfungi:YCR083W(gene)|ensemblfungi:YCR083W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0015036"(disulfide oxidoreductase activity)|go:"GO:0034599"(cellular response to oxidative stress)|rcsb pdb:5YKW|sgd:YCR083W(identity)	-	comment:mint	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:+TNQLExkhmC1NWqsE240Cx7zFVU9606	rogid:g0xjGf9GvJRl8iv2qoT5tOs7jXI559292	intact-crc:F4822C14E5D4A151|rigid:2zq189Faq2pyv39vLJcAMbQ4yiY	false	sufficient binding region:11-594	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P25372	uniprotkb:Q8IUQ4-2	intact:EBI-19616|uniprotkb:D6VR84|ensemblfungi:YCR083W	intact:EBI-11522811|ensembl:ENSP00000349156	psi-mi:trx3_yeast(display_long)|uniprotkb:TRX3(gene name)|psi-mi:TRX3(display_short)|uniprotkb:YCR83W(orf name)|uniprotkb:YCR083W(locus name)	psi-mi:q8iuq4-2(display_long)|uniprotkb:SIAH1(gene name)|psi-mi:SIAH1(display_short)|uniprotkb:HUMSIAH(gene name synonym)|uniprotkb:Seven in absentia homolog 1(gene name synonym)|uniprotkb:Siah-1a(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase SIAH1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11539812|imex:IM-24995-1836	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR036249|refseq:NP_010006.1|sgd:S000000679|interpro:IPR017937|interpro:IPR013766(Thioredoxin domain)|rcsb pdb:2OE0|rcsb pdb:2OE1|rcsb pdb:2OE3|ensemblfungi:YCR083W(gene)|ensemblfungi:YCR083W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0015036"(disulfide oxidoreductase activity)|go:"GO:0034599"(cellular response to oxidative stress)|rcsb pdb:5YKW|sgd:YCR083W(identity)	intact:EBI-747107(isoform-parent)|ensembl:ENSG00000196470(gene)|ensembl:ENST00000356721(transcript)|uniprotkb:Q8IUQ4-2(isoform-parent)|entrezgene/locuslink:6477(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:g0xjGf9GvJRl8iv2qoT5tOs7jXI559292	rogid:M4q06jVbWuq1mGMXvtuFBaMEgZM9606	intact-crc:4177FD8BAF332B89|rigid:ag+O9md4JZaSgB2+97fHyAL1Ft8	false	-	sufficient binding region:32-313	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P25372	uniprotkb:Q5T124-6	intact:EBI-19616|uniprotkb:D6VR84|ensemblfungi:YCR083W	intact:EBI-11524408	psi-mi:trx3_yeast(display_long)|uniprotkb:TRX3(gene name)|psi-mi:TRX3(display_short)|uniprotkb:YCR83W(orf name)|uniprotkb:YCR083W(locus name)	psi-mi:q5t124-6(display_long)|uniprotkb:UBXN11(gene name)|psi-mi:UBXN11(display_short)|uniprotkb:Colorectal tumor-associated antigen COA-1(gene name synonym)|uniprotkb:SOC(gene name synonym)|uniprotkb:Socius(gene name synonym)|uniprotkb:UBX domain-containing protein 5(gene name synonym)|uniprotkb:UBXD5(gene name synonym)|uniprotkb:PP2243(orf name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11539803|imex:IM-24995-1835	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR036249|refseq:NP_010006.1|sgd:S000000679|interpro:IPR017937|interpro:IPR013766(Thioredoxin domain)|rcsb pdb:2OE0|rcsb pdb:2OE1|rcsb pdb:2OE3|ensemblfungi:YCR083W(gene)|ensemblfungi:YCR083W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0015036"(disulfide oxidoreductase activity)|go:"GO:0034599"(cellular response to oxidative stress)|rcsb pdb:5YKW|sgd:YCR083W(identity)	intact:EBI-746004(isoform-parent)|uniprotkb:Q5T124-6(isoform-parent)|entrezgene/locuslink:91544(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:g0xjGf9GvJRl8iv2qoT5tOs7jXI559292	rogid:1YSjG/p2ihcjl4P8KdPCaX2HxiY9606	intact-crc:1D84D57F64F9CBBF|rigid:u+mMQM8pDMXQxLofCI551fVRpVk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q15654	uniprotkb:P25372	intact:EBI-742327|uniprotkb:O15170|uniprotkb:O15275|uniprotkb:Q9BTB2|uniprotkb:Q9BUE5|uniprotkb:Q9BXP3|uniprotkb:Q9UNT4|uniprotkb:A4D2E7|ensembl:ENSP00000200457|uniprotkb:F2ZC07|uniprotkb:F2ZC08	intact:EBI-19616|uniprotkb:D6VR84|ensemblfungi:YCR083W	psi-mi:trip6_human(display_long)|uniprotkb:TRIP6(gene name)|psi-mi:TRIP6(display_short)|uniprotkb:OIP1(gene name synonym)|uniprotkb:Opa-interacting protein 1(gene name synonym)|uniprotkb:Zyxin-related protein 1(gene name synonym)	psi-mi:trx3_yeast(display_long)|uniprotkb:TRX3(gene name)|psi-mi:TRX3(display_short)|uniprotkb:YCR83W(orf name)|uniprotkb:YCR083W(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11539793|imex:IM-24995-1834	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003293.2|ensembl:ENSP00000200457|ensembl:ENST00000417475|ensembl:ENSP00000413817|ensembl:ENST00000437505|ensembl:ENSP00000410736|ensembl:ENST00000619988|ensembl:ENSP00000479865|ensembl:ENSG00000087077(gene)|ensembl:ENST00000200457(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003723"(RNA binding)|go:"GO:0005149"(interleukin-1 receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0019900"(kinase binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0043009"(chordate embryonic development)|go:"GO:0046872"(metal ion binding)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|interpro:IPR001781(Zinc finger, LIM-type)|mint:Q15654|rcsb pdb:1X61|rcsb pdb:2DLO|dip:DIP-34466N|entrezgene/locuslink:7205(identity)	interpro:IPR036249|refseq:NP_010006.1|sgd:S000000679|interpro:IPR017937|interpro:IPR013766(Thioredoxin domain)|rcsb pdb:2OE0|rcsb pdb:2OE1|rcsb pdb:2OE3|ensemblfungi:YCR083W(gene)|ensemblfungi:YCR083W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0015036"(disulfide oxidoreductase activity)|go:"GO:0034599"(cellular response to oxidative stress)|rcsb pdb:5YKW|sgd:YCR083W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:9Okf3b6sMMwX5awAx991GN9iSsQ9606	rogid:g0xjGf9GvJRl8iv2qoT5tOs7jXI559292	intact-crc:43F71FF8DA1270BE|rigid:LQ5IHqe2DXnYjM69+r3vayu38eE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P25372	uniprotkb:Q96BR9	intact:EBI-19616|uniprotkb:D6VR84|ensemblfungi:YCR083W	intact:EBI-742740|uniprotkb:Q8IUL5|uniprotkb:Q8IWR9|uniprotkb:Q8N2Y5|uniprotkb:Q96BX0|ensembl:ENSP00000362609	psi-mi:trx3_yeast(display_long)|uniprotkb:TRX3(gene name)|psi-mi:TRX3(display_short)|uniprotkb:YCR83W(orf name)|uniprotkb:YCR083W(locus name)	psi-mi:zbt8a_human(display_long)|uniprotkb:ZBTB8A(gene name)|psi-mi:ZBTB8A(display_short)|uniprotkb:BOZF1(gene name synonym)|uniprotkb:BTB/POZ and zinc-finger domain-containing factor(gene name synonym)|uniprotkb:BTB/POZ and zinc-finger domains factor on chromosome 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11539872|imex:IM-24995-1842	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR036249|refseq:NP_010006.1|sgd:S000000679|interpro:IPR017937|interpro:IPR013766(Thioredoxin domain)|rcsb pdb:2OE0|rcsb pdb:2OE1|rcsb pdb:2OE3|ensemblfungi:YCR083W(gene)|ensemblfungi:YCR083W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0015036"(disulfide oxidoreductase activity)|go:"GO:0034599"(cellular response to oxidative stress)|rcsb pdb:5YKW|sgd:YCR083W(identity)	ensembl:ENSG00000160062(gene)|ensembl:ENST00000373510(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|refseq:NP_001035531.2|refseq:NP_001278425.1|entrezgene/locuslink:653121(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:g0xjGf9GvJRl8iv2qoT5tOs7jXI559292	rogid:tsrPT2tHvuBryODKgRXnceXz9s09606	intact-crc:936FC58A14010535|rigid:53vtLDth6ciX/tVN2LjZ7vKzi6s	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8NHQ1	uniprotkb:P25372	intact:EBI-739624|ensembl:ENSP00000264982|ensembl:ENSP00000419231|uniprotkb:Q96B31|uniprotkb:Q9H2C3|uniprotkb:Q9H2Z1|uniprotkb:Q9H940|uniprotkb:D3DNE9|uniprotkb:B7Z5I8|uniprotkb:B7Z7E8|uniprotkb:F5GZX8	intact:EBI-19616|uniprotkb:D6VR84|ensemblfungi:YCR083W	psi-mi:cep70_human(display_long)|uniprotkb:CEP70(gene name)|psi-mi:CEP70(display_short)|uniprotkb:BITE(gene name synonym)|uniprotkb:p10-binding protein(gene name synonym)	psi-mi:trx3_yeast(display_long)|uniprotkb:TRX3(gene name)|psi-mi:TRX3(display_short)|uniprotkb:YCR83W(orf name)|uniprotkb:YCR083W(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11539863|imex:IM-24995-1841	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114107(gene)|ensembl:ENST00000264982(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|interpro:IPR019734|interpro:IPR037692|mint:Q8NHQ1|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|ensembl:ENST00000484888(transcript)|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_077817.2|refseq:XP_016862764.1|refseq:NP_001275893.1|refseq:NP_001275894.1|refseq:NP_001275895.1|refseq:NP_001275896.1|refseq:NP_001307527.1|refseq:NP_001307529.1|entrezgene/locuslink:80321(identity)	interpro:IPR036249|refseq:NP_010006.1|sgd:S000000679|interpro:IPR017937|interpro:IPR013766(Thioredoxin domain)|rcsb pdb:2OE0|rcsb pdb:2OE1|rcsb pdb:2OE3|ensemblfungi:YCR083W(gene)|ensemblfungi:YCR083W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0015036"(disulfide oxidoreductase activity)|go:"GO:0034599"(cellular response to oxidative stress)|rcsb pdb:5YKW|sgd:YCR083W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:S4yveQWcvdVtAUX65gqrJ5Dv0Mc9606	rogid:g0xjGf9GvJRl8iv2qoT5tOs7jXI559292	intact-crc:B56A13BA189675EB|rigid:USumgpr/MOfPlWxaf3nEjvTt9Sw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8NF99-2	uniprotkb:P25372	intact:EBI-11524467|ensembl:ENSP00000261333	intact:EBI-19616|uniprotkb:D6VR84|ensemblfungi:YCR083W	psi-mi:q8nf99-2(display_long)|uniprotkb:ZNF47(gene name synonym)|uniprotkb:ZSCAN15(gene name synonym)|uniprotkb:Zinc finger and SCAN domain-containing protein 15(gene name synonym)|uniprotkb:Zinc finger protein 47(gene name synonym)|uniprotkb:ZNF397(gene name)|psi-mi:ZNF397(display_short)	psi-mi:trx3_yeast(display_long)|uniprotkb:TRX3(gene name)|psi-mi:TRX3(display_short)|uniprotkb:YCR83W(orf name)|uniprotkb:YCR083W(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11539854|imex:IM-24995-1840	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-10213894(isoform-parent)|ensembl:ENSG00000186812(gene)|ensembl:ENST00000261333(transcript)|uniprotkb:Q8NF99-2(isoform-parent)|entrezgene/locuslink:84307(identity)	interpro:IPR036249|refseq:NP_010006.1|sgd:S000000679|interpro:IPR017937|interpro:IPR013766(Thioredoxin domain)|rcsb pdb:2OE0|rcsb pdb:2OE1|rcsb pdb:2OE3|ensemblfungi:YCR083W(gene)|ensemblfungi:YCR083W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0015036"(disulfide oxidoreductase activity)|go:"GO:0034599"(cellular response to oxidative stress)|rcsb pdb:5YKW|sgd:YCR083W(identity)	-	isoform-comment:No experimental confirmation available.	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:CGdD3rsdZjS7lhobp1xohK8ewPg9606	rogid:g0xjGf9GvJRl8iv2qoT5tOs7jXI559292	intact-crc:9C7FAD5A6EEB8EF8|rigid:b8nkJhl66djEkj5zPYbYu0c2h4g	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8N9N5-2	uniprotkb:P25372	intact:EBI-11524452|ensembl:ENSP00000347125	intact:EBI-19616|uniprotkb:D6VR84|ensemblfungi:YCR083W	psi-mi:q8n9n5-2(display_long)|uniprotkb:BANP(gene name)|psi-mi:BANP(display_short)|uniprotkb:BEN domain-containing protein 1(gene name synonym)|uniprotkb:BEND1(gene name synonym)|uniprotkb:Btg3-associated nuclear protein(gene name synonym)|uniprotkb:SMAR1(gene name synonym)|uniprotkb:Scaffold/matrix-associated region-1-binding protein(gene name synonym)	psi-mi:trx3_yeast(display_long)|uniprotkb:TRX3(gene name)|psi-mi:TRX3(display_short)|uniprotkb:YCR83W(orf name)|uniprotkb:YCR083W(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11539845|imex:IM-24995-1839	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000172530(gene)|ensembl:ENST00000355022(transcript)|intact:EBI-744695(isoform-parent)|uniprotkb:Q8N9N5-2(isoform-parent)|entrezgene/locuslink:54971(identity)	interpro:IPR036249|refseq:NP_010006.1|sgd:S000000679|interpro:IPR017937|interpro:IPR013766(Thioredoxin domain)|rcsb pdb:2OE0|rcsb pdb:2OE1|rcsb pdb:2OE3|ensemblfungi:YCR083W(gene)|ensemblfungi:YCR083W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0015036"(disulfide oxidoreductase activity)|go:"GO:0034599"(cellular response to oxidative stress)|rcsb pdb:5YKW|sgd:YCR083W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:ESe6iCAhvq+i57fQHz3rGyg6UOo9606	rogid:g0xjGf9GvJRl8iv2qoT5tOs7jXI559292	intact-crc:8D5AB3854D2E3BDD|rigid:D2t9mdT178XNXvZzowu3vAPVZPE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8N7W2-2	uniprotkb:P25372	intact:EBI-10181188|ensembl:ENSP00000367868	intact:EBI-19616|uniprotkb:D6VR84|ensemblfungi:YCR083W	psi-mi:q8n7w2-2(display_long)|uniprotkb:C10orf30(gene name synonym)|uniprotkb:BEND7(gene name)|psi-mi:BEND7(display_short)	psi-mi:trx3_yeast(display_long)|uniprotkb:TRX3(gene name)|psi-mi:TRX3(display_short)|uniprotkb:YCR83W(orf name)|uniprotkb:YCR083W(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11539834|imex:IM-24995-1838	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000165626(gene)|ensembl:ENST00000378605(transcript)|intact:EBI-743382(isoform-parent)|uniprotkb:Q8N7W2-2(isoform-parent)|entrezgene/locuslink:222389(identity)	interpro:IPR036249|refseq:NP_010006.1|sgd:S000000679|interpro:IPR017937|interpro:IPR013766(Thioredoxin domain)|rcsb pdb:2OE0|rcsb pdb:2OE1|rcsb pdb:2OE3|ensemblfungi:YCR083W(gene)|ensemblfungi:YCR083W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0015036"(disulfide oxidoreductase activity)|go:"GO:0034599"(cellular response to oxidative stress)|rcsb pdb:5YKW|sgd:YCR083W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:p6qrTn80hLyVU0W2Tvwn50Q4m5I9606	rogid:g0xjGf9GvJRl8iv2qoT5tOs7jXI559292	intact-crc:2A2C326C416C3B2D|rigid:o0fB5iTlqwudH6QuYtl3LKu7IBE	false	sufficient binding region:10-374	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P25375	uniprotkb:Q9NPC3	intact:EBI-13932|uniprotkb:E9P942|uniprotkb:D6VQW0|ensemblfungi:YCL057W	intact:EBI-745269|ensembl:ENSP00000337396|ensembl:ENSP00000351810|ensembl:ENSP00000381226|ensembl:ENSP00000381229|ensembl:ENSP00000381235|ensembl:ENSP00000409896	psi-mi:prtd_yeast(display_long)|uniprotkb:PRD1(gene name)|psi-mi:PRD1(display_short)|uniprotkb:YCL057W(locus name)|uniprotkb:YCL57W(orf name)|uniprotkb:Protease D(gene name synonym)|uniprotkb:Proteinase yscD(gene name synonym)|uniprotkb:Oligopeptidase YSCD(gene name synonym)	psi-mi:cip1_human(display_long)|uniprotkb:Cyclin-B1-interacting protein 1(gene name synonym)|uniprotkb:Human enhancer of invasion 10(gene name synonym)|uniprotkb:CCNB1IP1(gene name)|psi-mi:CCNB1IP1(display_short)|uniprotkb:C14orf18(gene name synonym)|uniprotkb:HEI10(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase CCNB1IP1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11539918|imex:IM-24995-1847	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009874.1|sgd:S000000562|ensemblfungi:YCL057W(gene)|ensemblfungi:YCL057W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006508"(proteolysis)|go:"GO:0006518"(peptide metabolic process)|go:"GO:0046872"(metal ion binding)|interpro:IPR001567(Peptidase M3A and M3B, thimet/oligopeptidase F)|interpro:IPR024077|interpro:IPR024079|interpro:IPR024080|reactome:R-SCE-983168|mint:P25375|dip:DIP-4938N|sgd:YCL057W(identity)	refseq:NP_067001.3|refseq:NP_878269.1|refseq:NP_878272.1|ensembl:ENSG00000100814(gene)|ensembl:ENST00000353689(transcript)|ensembl:ENST00000358932(transcript)|ensembl:ENST00000398160(transcript)|ensembl:ENST00000398163(transcript)|ensembl:ENST00000398169(transcript)|ensembl:ENST00000437553(transcript)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001825"(blastocyst formation)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0007286"(spermatid development)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051026"(chiasma assembly)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR042448|entrezgene/locuslink:57820(identity)	-	crc64:340910B7FDAFBE37	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:WXFCl27lNmdlkUaDqmVZl0u4bGg559292	rogid:UyF392Md+IuOz5wp9kW2Pjr2ZzY9606	intact-crc:5CA7748C77829E3C|rigid:81gO47TC1Ngvuv+dQnrkjbeuJPc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P25372	uniprotkb:Q9Y3Q8	intact:EBI-19616|uniprotkb:D6VR84|ensemblfungi:YCR083W	intact:EBI-739485|uniprotkb:A8MWR6|ensembl:ENSP00000300181|uniprotkb:A4D2C3|uniprotkb:D6W5V9	psi-mi:trx3_yeast(display_long)|uniprotkb:TRX3(gene name)|psi-mi:TRX3(display_short)|uniprotkb:YCR83W(orf name)|uniprotkb:YCR083W(locus name)	psi-mi:t22d4_human(display_long)|uniprotkb:TSC22D4(gene name)|psi-mi:TSC22D4(display_short)|uniprotkb:TILZ2(gene name synonym)|uniprotkb:TSC22-related-inducible leucine zipper protein 2(gene name synonym)|uniprotkb:Tsc-22-like protein THG-1(gene name synonym)|uniprotkb:THG1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11539908|imex:IM-24995-1846	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR036249|refseq:NP_010006.1|sgd:S000000679|interpro:IPR017937|interpro:IPR013766(Thioredoxin domain)|rcsb pdb:2OE0|rcsb pdb:2OE1|rcsb pdb:2OE3|ensemblfungi:YCR083W(gene)|ensemblfungi:YCR083W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0015036"(disulfide oxidoreductase activity)|go:"GO:0034599"(cellular response to oxidative stress)|rcsb pdb:5YKW|sgd:YCR083W(identity)	ensembl:ENSG00000166925(gene)|ensembl:ENST00000300181(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006970"(response to osmotic stress)|interpro:IPR000580(TSC-22 / Dip / Bun)|interpro:IPR042553|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|refseq:NP_112197.1|refseq:NP_001289972.1|entrezgene/locuslink:81628(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:g0xjGf9GvJRl8iv2qoT5tOs7jXI559292	rogid:eL12cHY76zEPOXzT1HFKPSckS8Y9606	intact-crc:08DE9D7881B4D013|rigid:YczFP5l/qUDh5ND1iOxBAW2Cp9w	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9NYB9-2	uniprotkb:P25372	intact:EBI-11096309|ensembl:ENSP00000261017	intact:EBI-19616|uniprotkb:D6VR84|ensemblfungi:YCR083W	psi-mi:q9nyb9-2(display_long)|uniprotkb:ABI2(gene name)|psi-mi:ABI2(display_short)|uniprotkb:ARGBPIA(gene name synonym)|uniprotkb:Abelson interactor 2(gene name synonym)|uniprotkb:Abl-binding protein 3(gene name synonym)|uniprotkb:Arg-binding protein 1(gene name synonym)	psi-mi:trx3_yeast(display_long)|uniprotkb:TRX3(gene name)|psi-mi:TRX3(display_short)|uniprotkb:YCR83W(orf name)|uniprotkb:YCR083W(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11539899|imex:IM-24995-1845	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-743598(isoform-parent)|ensembl:ENSG00000138443(gene)|ensembl:ENST00000261017(transcript)|uniprotkb:Q9NYB9-2(isoform-parent)|entrezgene/locuslink:10152(identity)	interpro:IPR036249|refseq:NP_010006.1|sgd:S000000679|interpro:IPR017937|interpro:IPR013766(Thioredoxin domain)|rcsb pdb:2OE0|rcsb pdb:2OE1|rcsb pdb:2OE3|ensemblfungi:YCR083W(gene)|ensemblfungi:YCR083W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0015036"(disulfide oxidoreductase activity)|go:"GO:0034599"(cellular response to oxidative stress)|rcsb pdb:5YKW|sgd:YCR083W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:VNi9aUeavD8+CCi+n1DXS+7mmbs9606	rogid:g0xjGf9GvJRl8iv2qoT5tOs7jXI559292	intact-crc:F5E3D8E3E6D5B52C|rigid:nwQyVIFS3EIBtCZK24g9kspA1yM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9NVV9	uniprotkb:P25372	intact:EBI-741515|uniprotkb:Q53FQ1|uniprotkb:Q6IA99|ensembl:ENSP00000254250|uniprotkb:A6NCB6|uniprotkb:D3DSY5|uniprotkb:H9KV49	intact:EBI-19616|uniprotkb:D6VR84|ensemblfungi:YCR083W	psi-mi:thap1_human(display_long)|uniprotkb:THAP1(gene name)|psi-mi:THAP1(display_short)	psi-mi:trx3_yeast(display_long)|uniprotkb:TRX3(gene name)|psi-mi:TRX3(display_short)|uniprotkb:YCR83W(orf name)|uniprotkb:YCR083W(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11539890|imex:IM-24995-1844	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060575.1|ensembl:ENSG00000131931(gene)|ensembl:ENST00000254250(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001650"(fibrillar center)|go:"GO:0001935"(endothelial cell proliferation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007049"(cell cycle)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016605"(PML body)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR006612(Zinc finger, C2CH-type)|interpro:IPR026516|interpro:IPR038441|mint:Q9NVV9|rcsb pdb:2JTG|rcsb pdb:2KO0|rcsb pdb:2L1G|refseq:NP_945354.1|entrezgene/locuslink:55145(identity)	interpro:IPR036249|refseq:NP_010006.1|sgd:S000000679|interpro:IPR017937|interpro:IPR013766(Thioredoxin domain)|rcsb pdb:2OE0|rcsb pdb:2OE1|rcsb pdb:2OE3|ensemblfungi:YCR083W(gene)|ensemblfungi:YCR083W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0015036"(disulfide oxidoreductase activity)|go:"GO:0034599"(cellular response to oxidative stress)|rcsb pdb:5YKW|sgd:YCR083W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:/KO90pu5tBnIVq9SMx1JYPXFCEQ9606	rogid:g0xjGf9GvJRl8iv2qoT5tOs7jXI559292	intact-crc:89DA52E963ECA518|rigid:gt2+hlOW9j2rlOxnM5RKPuBqBs4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P25372	uniprotkb:Q9BRK4	intact:EBI-19616|uniprotkb:D6VR84|ensemblfungi:YCR083W	intact:EBI-741037|ensembl:ENSP00000359240|ensembl:ENSP00000359243|uniprotkb:Q8N3I0|uniprotkb:Q96J79|uniprotkb:Q96JL2|uniprotkb:B1AL14|uniprotkb:D3DR72	psi-mi:trx3_yeast(display_long)|uniprotkb:TRX3(gene name)|psi-mi:TRX3(display_short)|uniprotkb:YCR83W(orf name)|uniprotkb:YCR083W(locus name)	psi-mi:lzts2_human(display_long)|uniprotkb:Protein LAPSER1(gene name synonym)|uniprotkb:LZTS2(gene name)|psi-mi:LZTS2(display_short)|uniprotkb:KIAA1813(gene name synonym)|uniprotkb:LAPSER1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11539881|imex:IM-24995-1843	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR036249|refseq:NP_010006.1|sgd:S000000679|interpro:IPR017937|interpro:IPR013766(Thioredoxin domain)|rcsb pdb:2OE0|rcsb pdb:2OE1|rcsb pdb:2OE3|ensemblfungi:YCR083W(gene)|ensemblfungi:YCR083W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0015036"(disulfide oxidoreductase activity)|go:"GO:0034599"(cellular response to oxidative stress)|rcsb pdb:5YKW|sgd:YCR083W(identity)	refseq:NP_115805.1|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030496"(midbody)|go:"GO:0031982"(vesicle)|go:"GO:0051013"(microtubule severing)|go:"GO:0051168"(nuclear export)|go:"GO:0051255"(spindle midzone assembly)|go:"GO:0060682"(primary ureteric bud growth)|go:"GO:0072197"(ureter morphogenesis)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|interpro:IPR028597|mint:Q9BRK4|ensembl:ENSG00000107816(gene)|ensembl:ENST00000370220(transcript)|ensembl:ENST00000370223(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0008285"(negative regulation of cell population proliferation)|refseq:XP_016872269.1|refseq:NP_001305028.1|refseq:NP_001305029.1|refseq:NP_001305030.1|refseq:XP_005270279.1|entrezgene/locuslink:84445(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:g0xjGf9GvJRl8iv2qoT5tOs7jXI559292	rogid:OaMJmnmfm6JniKUJeyg7fS6zRcw9606	intact-crc:C35CBE7648A9EEC7|rigid:v5gLRQMqyctMImI8qbPOhcFVTqE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P25377	uniprotkb:P61371	intact:EBI-2347652|uniprotkb:D6VRA5|ensemblfungi:YCR105W	intact:EBI-3906896|uniprotkb:P47894|uniprotkb:P20663|ensembl:ENSP00000230658	psi-mi:adh7_yeast(display_long)|uniprotkb:ADH7(gene name)|psi-mi:ADH7(display_short)|uniprotkb:NADP-dependent alcohol dehydrogenase VII(gene name synonym)|uniprotkb:YCR105W(locus name)	psi-mi:isl1_human(display_long)|uniprotkb:ISL1(gene name)|psi-mi:ISL1(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11539954|imex:IM-24995-1851	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010030.1|sgd:S000000702|dip:DIP-7661N|mint:P25377|ensemblfungi:YCR105W(gene)|ensemblfungi:YCR105W_mRNA(transcript)|go:"GO:0006066"(alcohol metabolic process)|go:"GO:0008106"("alcohol dehydrogenase (NADP+) activity")|go:"GO:0008270"(zinc ion binding)|go:"GO:0016616"(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|interpro:IPR002328(Alcohol dehydrogenase, zinc-containing, conserved site)|interpro:IPR011032(GroES-like)|interpro:IPR013149(Alcohol dehydrogenase, zinc-binding)|interpro:IPR013154(Alcohol dehydrogenase GroES-like)|interpro:IPR020843|interpro:IPR029752|interpro:IPR036291|sgd:YCR105W(identity)	refseq:NP_002193.2|ensembl:ENSP00000230658|ensembl:ENSG00000016082(gene)|ensembl:ENST00000230658(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001755"(neural crest cell migration)|go:"GO:0003139"(secondary heart field specification)|go:"GO:0003148"(outflow tract septum morphogenesis)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0003203"(endocardial cushion morphogenesis)|go:"GO:0003215"(cardiac right ventricle morphogenesis)|go:"GO:0003266"(regulation of secondary heart field cardioblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007409"(axonogenesis)|go:"GO:0007507"(heart development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010575"(positive regulation of vascular endothelial growth factor production)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0021520"(spinal cord motor neuron cell fate specification)|go:"GO:0021522"(spinal cord motor neuron differentiation)|go:"GO:0021524"(visceral motor neuron differentiation)|go:"GO:0021559"(trigeminal nerve development)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0031016"(pancreas development)|go:"GO:0031103"(axon regeneration)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0031290"(retinal ganglion cell axon guidance)|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048665"(neuron fate specification)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0048880"(sensory system development)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0048936"(peripheral nervous system neuron axonogenesis)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0060037"(pharyngeal system development)|go:"GO:0060379"(cardiac muscle cell myoblast differentiation)|go:"GO:0060384"(innervation)|go:"GO:0060413"(atrial septum morphogenesis)|go:"GO:0060913"(cardiac cell fate determination)|go:"GO:0060931"(sinoatrial node cell development)|go:"GO:0032725"(positive regulation of granulocyte macrophage colony-stimulating factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032730"(positive regulation of interleukin-1 alpha production)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0071657"(positive regulation of granulocyte colony-stimulating factor production)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1901258"(positive regulation of macrophage colony-stimulating factor production)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001356(Homeobox)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|mint:P61371|reactome:R-HSA-400511|reactome:R-HSA-9010553|entrezgene/locuslink:3670(identity)	-	crc64:BFB0E6C5F93D3F07	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:PGCt+bqhn63vUVgS5IKrrOukXgg559292	rogid:1eir7wLzkoqlwl4AfQuBtjjiyd09606	intact-crc:17C5C8A0A899285A|rigid:EdWNISKdl+iTNjPZeQZyVi1XzTo	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P43365	uniprotkb:P25377	intact:EBI-749530|uniprotkb:Q9NSD3|intact:EBI-10178394|uniprotkb:Q6FHH8|ensembl:ENSP00000350592|ensembl:ENSP00000377447|ensembl:ENSP00000377478	intact:EBI-2347652|uniprotkb:D6VRA5|ensemblfungi:YCR105W	psi-mi:magac_human(display_long)|uniprotkb:MAGE-12 antigen(gene name synonym)|uniprotkb:MAGE12F antigen(gene name synonym)|uniprotkb:Cancer/testis antigen 1.12(gene name synonym)|uniprotkb:MAGEA12(gene name)|psi-mi:MAGEA12(display_short)|uniprotkb:MAGE12(gene name synonym)	psi-mi:adh7_yeast(display_long)|uniprotkb:ADH7(gene name)|psi-mi:ADH7(display_short)|uniprotkb:NADP-dependent alcohol dehydrogenase VII(gene name synonym)|uniprotkb:YCR105W(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11539945|imex:IM-24995-1850	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001159858.1|refseq:NP_001159859.1|refseq:NP_005358.2|ensembl:ENSG00000213401(gene)|ensembl:ENST00000357916(transcript)|ensembl:ENST00000393869(transcript)|ensembl:ENST00000393900(transcript)|interpro:IPR002190(MAGE protein)|interpro:IPR021072|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|entrezgene/locuslink:4111(identity)	refseq:NP_010030.1|sgd:S000000702|dip:DIP-7661N|mint:P25377|ensemblfungi:YCR105W(gene)|ensemblfungi:YCR105W_mRNA(transcript)|go:"GO:0006066"(alcohol metabolic process)|go:"GO:0008106"("alcohol dehydrogenase (NADP+) activity")|go:"GO:0008270"(zinc ion binding)|go:"GO:0016616"(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|interpro:IPR002328(Alcohol dehydrogenase, zinc-containing, conserved site)|interpro:IPR011032(GroES-like)|interpro:IPR013149(Alcohol dehydrogenase, zinc-binding)|interpro:IPR013154(Alcohol dehydrogenase GroES-like)|interpro:IPR020843|interpro:IPR029752|interpro:IPR036291|sgd:YCR105W(identity)	-	-	crc64:BFB0E6C5F93D3F07	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:3/Jxz2VsFOb67RWqWj3xbTrw3s49606	rogid:PGCt+bqhn63vUVgS5IKrrOukXgg559292	intact-crc:D1E2A71B0192E469|rigid:keh5VjBC/XE8jCKzGiHnaFBh6e4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P25377	uniprotkb:P38432	intact:EBI-2347652|uniprotkb:D6VRA5|ensemblfungi:YCR105W	intact:EBI-945751|uniprotkb:B2R931|ensembl:ENSP00000240316	psi-mi:adh7_yeast(display_long)|uniprotkb:ADH7(gene name)|psi-mi:ADH7(display_short)|uniprotkb:NADP-dependent alcohol dehydrogenase VII(gene name synonym)|uniprotkb:YCR105W(locus name)	psi-mi:coil_human(display_long)|uniprotkb:COIL(gene name)|psi-mi:COIL(display_short)|uniprotkb:CLN80(gene name synonym)|uniprotkb:p80-coilin(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11539936|imex:IM-24995-1849	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010030.1|sgd:S000000702|dip:DIP-7661N|mint:P25377|ensemblfungi:YCR105W(gene)|ensemblfungi:YCR105W_mRNA(transcript)|go:"GO:0006066"(alcohol metabolic process)|go:"GO:0008106"("alcohol dehydrogenase (NADP+) activity")|go:"GO:0008270"(zinc ion binding)|go:"GO:0016616"(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|interpro:IPR002328(Alcohol dehydrogenase, zinc-containing, conserved site)|interpro:IPR011032(GroES-like)|interpro:IPR013149(Alcohol dehydrogenase, zinc-binding)|interpro:IPR013154(Alcohol dehydrogenase GroES-like)|interpro:IPR020843|interpro:IPR029752|interpro:IPR036291|sgd:YCR105W(identity)	refseq:NP_004636.1|dip:DIP-38503N|ensembl:ENSG00000121058(gene)|ensembl:ENST00000240316(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0015030"(Cajal body)|go:"GO:0016020"(membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0030619"(U1 snRNA binding)|go:"GO:0030620"(U2 snRNA binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR024822|interpro:IPR031722|mint:P38432|entrezgene/locuslink:8161(identity)	-	crc64:BFB0E6C5F93D3F07	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:PGCt+bqhn63vUVgS5IKrrOukXgg559292	rogid:hd5p6AbyA/GYNEeca99Mdb41qM09606	intact-crc:7076F038A2A14A01|rigid:f+UCxJGH8DarSYA0nEMYqaC7YRI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O76083-2	uniprotkb:P25377	intact:EBI-11524542|ensembl:ENSP00000335242	intact:EBI-2347652|uniprotkb:D6VRA5|ensemblfungi:YCR105W	psi-mi:o76083-2(display_long)|uniprotkb:PDE9A(gene name)|psi-mi:PDE9A(display_short)	psi-mi:adh7_yeast(display_long)|uniprotkb:ADH7(gene name)|psi-mi:ADH7(display_short)|uniprotkb:NADP-dependent alcohol dehydrogenase VII(gene name synonym)|uniprotkb:YCR105W(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11539927|imex:IM-24995-1848	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-742764(isoform-parent)|ensembl:ENSG00000160191(gene)|ensembl:ENST00000335512(transcript)|uniprotkb:O76083-2(isoform-parent)|entrezgene/locuslink:5152(identity)	refseq:NP_010030.1|sgd:S000000702|dip:DIP-7661N|mint:P25377|ensemblfungi:YCR105W(gene)|ensemblfungi:YCR105W_mRNA(transcript)|go:"GO:0006066"(alcohol metabolic process)|go:"GO:0008106"("alcohol dehydrogenase (NADP+) activity")|go:"GO:0008270"(zinc ion binding)|go:"GO:0016616"(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|interpro:IPR002328(Alcohol dehydrogenase, zinc-containing, conserved site)|interpro:IPR011032(GroES-like)|interpro:IPR013149(Alcohol dehydrogenase, zinc-binding)|interpro:IPR013154(Alcohol dehydrogenase GroES-like)|interpro:IPR020843|interpro:IPR029752|interpro:IPR036291|sgd:YCR105W(identity)	-	-	crc64:BFB0E6C5F93D3F07	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:nTzgeYGOwTM/7VJUgxSnlnDiCFo9606	rogid:PGCt+bqhn63vUVgS5IKrrOukXgg559292	intact-crc:B337A5270DE656F0|rigid:JbiTJHJ1iOe/jhMhIOce+Tu0vtY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P25566	uniprotkb:Q12800	intact:EBI-21713|uniprotkb:D6VQY2|ensemblfungi:YCL033C	intact:EBI-717422|uniprotkb:Q12801|uniprotkb:Q9UD77|uniprotkb:A8K5E9|uniprotkb:Q9UD75|ensembl:ENSP00000257915	psi-mi:mxr2_yeast(display_long)|uniprotkb:YCL033C(locus name)|uniprotkb:YCL33C(orf name)|uniprotkb:MXR2(gene name)|psi-mi:MXR2(display_short)|uniprotkb:MSRB(gene name synonym)	psi-mi:tfcp2_human(display_long)|uniprotkb:Transcription factor LSF(gene name synonym)|uniprotkb:SAA3 enhancer factor(gene name synonym)|uniprotkb:TFCP2(gene name)|psi-mi:TFCP2(display_short)|uniprotkb:LSF(gene name synonym)|uniprotkb:SEF(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11539999|imex:IM-24995-1856	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009897.1|sgd:S000000538|dip:DIP-4861N|ensemblfungi:YCL033C(gene)|ensemblfungi:YCL033C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0030091"(protein repair)|go:"GO:0033743"("peptide-methionine (R)-S-oxide reductase activity")|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0046872"(metal ion binding)|interpro:IPR002579(Methionine sulphoxide reductase B)|interpro:IPR011057(Mss4-like)|interpro:IPR028427|sgd:YCL033C(identity)	refseq:NP_001166923.1|refseq:NP_001166924.1|refseq:NP_005644.2|ensembl:ENSG00000135457(gene)|ensembl:ENST00000257915(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR007604(CP2 transcription factor)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR037599|interpro:IPR041418|mint:Q12800|entrezgene/locuslink:7024(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:iqa3p6vw9Ah3pxugESw1TdFd6bU559292	rogid:M7mQ08NDYxuawmUEKRgjSdIr+Og9606	intact-crc:7EDEFCC2C1AB7CDF|rigid:T81VuNmA06E5rN2a8yPQld5qp7s	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P25515	uniprotkb:P63279	intact:EBI-7739233|ensemblfungi:YEL027W|intact:MINT-1353979|uniprotkb:D3DLM1	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	psi-mi:vatl1_yeast(display_long)|uniprotkb:VMA3(gene name)|psi-mi:VMA3(display_short)|uniprotkb:CLS7(gene name synonym)|uniprotkb:CUP5(gene name synonym)|uniprotkb:GEF2(gene name synonym)|uniprotkb:YEL027W(locus name)|uniprotkb:Vacuolar proton pump c subunit(gene name synonym)|uniprotkb:V-ATPase 16 kDa proteolipid subunit 1(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor 2(gene name synonym)	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11539990|imex:IM-24995-1855	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR002379(ATPase, F0/V0 complex, subunit C)|interpro:IPR011555(ATPase, V0 complex, proteolipid subunit C, eukaryotic)|interpro:IPR035921|rcsb pdb:3J9T|rcsb pdb:3J9U|rcsb pdb:3J9V|rcsb pdb:5TJ5|rcsb pdb:5VOX|rcsb pdb:5VOY|rcsb pdb:5VOZ|rcsb pdb:6C6L|rcsb pdb:6M0R|rcsb pdb:6M0S|rcsb pdb:6O7T|rcsb pdb:6O7U|rcsb pdb:6O7V|rcsb pdb:6O7W|rcsb pdb:6O7X|rcsb pdb:6PE4|rcsb pdb:6PE5|reactome:R-SCE-1222556|reactome:R-SCE-6798695|reactome:R-SCE-77387|reactome:R-SCE-917977|reactome:R-SCE-9639288|ensemblfungi:YEL027W(gene)|ensemblfungi:YEL027W_mRNA(transcript)|go:"GO:0000220"(vacuolar proton-transporting V-type ATPase, V0 domain)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006878"(cellular copper ion homeostasis)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0006897"(endocytosis)|go:"GO:0007033"(vacuole organization)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR000245(ATPase, V0 complex, proteolipid subunit C,)|sgd:S000000753|mint:P25515|refseq:NP_010887.3|dip:DIP-8123N|sgd:YEL027W(identity)	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N|entrezgene/locuslink:7329(identity)	-	crc64:FB8A142FFA1FA964|comment:mint|function:Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. It is an electrogenic proton pump that generates a proton motive force of 180 mv, inside positive and acidic, in the vacuolar membrane vesicles	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:MAXfIOCwZyeV4Vy1T0eKqIbS4ZQ559292	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	intact-crc:5753503FEA4C69AB|rigid:+lYpw9WhGGP2lQbI4FItuk7aeGw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P25453	uniprotkb:P63279	intact:EBI-5955|uniprotkb:D3DM88|ensemblfungi:YER179W	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	psi-mi:dmc1_yeast(display_long)|uniprotkb:YER179W(locus name)|uniprotkb:DMC1(gene name)|psi-mi:DMC1(display_short)|uniprotkb:ISC2(gene name synonym)	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11539981|imex:IM-24995-1854	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011106.1|sgd:S000000981|dip:DIP-110N|mint:P25453|ensemblfungi:YER179W(gene)|ensemblfungi:YER179W_mRNA(transcript)|go:"GO:0000150"(DNA strand exchange activity)|go:"GO:0000709"(meiotic joint molecule formation)|go:"GO:0000730"(DNA recombinase assembly)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006312"(mitotic recombination)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0030435"(sporulation resulting in formation of a cellular spore)|go:"GO:0042030"(ATPase inhibitor activity)|go:"GO:0042148"(strand invasion)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070192"(chromosome organization involved in meiotic cell cycle)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010995(DNA repair Rad51/transcription factor NusA, alpha-helical)|interpro:IPR011940(Meiotic recombinase Dmc1)|interpro:IPR013632(Rad51, C-terminal)|interpro:IPR016467(DNA repair and recombination, RecA-like)|interpro:IPR020587|interpro:IPR020588|interpro:IPR027417|interpro:IPR033925|sgd:YER179W(identity)	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N|entrezgene/locuslink:7329(identity)	-	crc64:00B0503D7FAF5CB3	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:tbn7/STS08gIJBzfUmIz/yPmBJ8559292	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	intact-crc:6DE29D0E27C22F76|rigid:3bEIEs4jkQOFMJU/UEvB+mRwNfU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P25385	uniprotkb:Q12846	intact:EBI-3735|uniprotkb:D6VY78|ensemblfungi:YLR078C	intact:EBI-744942|uniprotkb:Q15525|ensembl:ENSP00000317714|uniprotkb:Q6FHE8|uniprotkb:A8MXY0	psi-mi:bos1_yeast(display_long)|uniprotkb:BOS1(gene name)|psi-mi:BOS1(display_short)|uniprotkb:YLR078C(locus name)|uniprotkb:L9449.9(orf name)|uniprotkb:Bet one suppressor 1(gene name synonym)	psi-mi:stx4_human(display_long)|uniprotkb:Renal carcinoma antigen NY-REN-31(gene name synonym)|uniprotkb:STX4(gene name)|psi-mi:STX4(display_short)|uniprotkb:STX4A(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11539972|imex:IM-24995-1853	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013179.1|sgd:S000004068|reactome:R-SCE-204005|reactome:R-SCE-5694530|reactome:R-SCE-6807878|dip:DIP-2020N|ensemblfungi:YLR078C(gene)|ensemblfungi:YLR078C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0006906"(vesicle fusion)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0031902"(late endosome membrane)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0048280"(vesicle fusion with Golgi apparatus)|interpro:IPR027027|sgd:YLR078C(identity)	ensembl:ENSG00000103496(gene)|refseq:NP_004595.2|ensembl:ENST00000313843(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0000322"(storage vacuole)|go:"GO:0002639"(positive regulation of immunoglobulin production)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005768"(endosome)|go:"GO:0005773"(vacuole)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006887"(exocytosis)|go:"GO:0006906"(vesicle fusion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016230"(sphingomyelin phosphodiesterase activator activity)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0032589"(neuron projection membrane)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035493"(SNARE complex assembly)|go:"GO:0035749"(myelin sheath adaxonal region)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0036477"(somatodendritic compartment)|go:"GO:0042581"(specific granule)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043197"(dendritic spine)|go:"GO:0043219"(lateral loop)|go:"GO:0043311"(positive regulation of eosinophil degranulation)|go:"GO:0045202"(synapse)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0048278"(vesicle docking)|go:"GO:0048284"(organelle fusion)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048787"(presynaptic active zone membrane)|go:"GO:0050921"(positive regulation of chemotaxis)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1902041"(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1903575"(cornified envelope assembly)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|reactome:R-HSA-114516|reactome:R-HSA-1236974|reactome:R-HSA-1445148|reactome:R-HSA-199992|reactome:R-HSA-449836|interpro:IPR006011(Syntaxin, N-terminal)|refseq:NP_001259025.1|entrezgene/locuslink:6810(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Rwf+Olm3mXTGhh/KZUgtVel+wzc559292	rogid:NvOLGIGe/XO2aDPSpdPzrtKniZY9606	intact-crc:08664F39021AC19E|rigid:h0WCNB/fcQEBEqbIlGx+UKyw0L8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P25377	uniprotkb:Q8WXE1-3	intact:EBI-2347652|uniprotkb:D6VRA5|ensemblfungi:YCR105W	intact:EBI-11524582|ensembl:ENSP00000400930	psi-mi:adh7_yeast(display_long)|uniprotkb:ADH7(gene name)|psi-mi:ADH7(display_short)|uniprotkb:NADP-dependent alcohol dehydrogenase VII(gene name synonym)|uniprotkb:YCR105W(locus name)	psi-mi:q8wxe1-3(display_long)|uniprotkb:ATRIP(gene name)|psi-mi:ATRIP(display_short)|uniprotkb:AGS1(gene name synonym)|uniprotkb:ATM and Rad3-related-interacting protein(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11539963|imex:IM-24995-1852	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010030.1|sgd:S000000702|dip:DIP-7661N|mint:P25377|ensemblfungi:YCR105W(gene)|ensemblfungi:YCR105W_mRNA(transcript)|go:"GO:0006066"(alcohol metabolic process)|go:"GO:0008106"("alcohol dehydrogenase (NADP+) activity")|go:"GO:0008270"(zinc ion binding)|go:"GO:0016616"(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|interpro:IPR002328(Alcohol dehydrogenase, zinc-containing, conserved site)|interpro:IPR011032(GroES-like)|interpro:IPR013149(Alcohol dehydrogenase, zinc-binding)|interpro:IPR013154(Alcohol dehydrogenase GroES-like)|interpro:IPR020843|interpro:IPR029752|interpro:IPR036291|sgd:YCR105W(identity)	intact:EBI-747353(isoform-parent)|ensembl:ENSG00000164053(gene)|ensembl:ENST00000412052(transcript)|entrezgene/locuslink:84126(identity)	-	crc64:BFB0E6C5F93D3F07	isoform-comment:No experimental confirmation available.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:PGCt+bqhn63vUVgS5IKrrOukXgg559292	rogid:NKCjy1jGZEySEhUOf8rJ6h9pyxY9606	intact-crc:FD1C850CBA5C841C|rigid:QIrliXieSc8Ux2A78vwZ+kw2xIU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P63279	uniprotkb:P25611	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	intact:EBI-22052|uniprotkb:D6VRA6|ensemblfungi:YCR106W	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:rds1_yeast(display_long)|uniprotkb:YCR106W(locus name)|uniprotkb:RDS1(gene name)|psi-mi:RDS1(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11540044|imex:IM-24995-1861	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N|entrezgene/locuslink:7329(identity)	refseq:NP_010031.1|sgd:S000000703|dip:DIP-2014N|ensemblfungi:YCR106W(gene)|ensemblfungi:YCR106W_mRNA(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009410"(response to xenobiotic stimulus)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR001138(Fungal transcriptional regulatory protein, N-terminal)|interpro:IPR036864|mint:P25611|sgd:YCR106W(identity)	-	-	crc64:7DF91D86AF08E4E3	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	rogid:1um+FEn46D2/f4P58Zo/rIQSEZU559292	intact-crc:FA3ACD4F64EF811B|rigid:tbMuMDUh0kZb/AIj+CkKwP4JPyw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P25586	uniprotkb:Q96BR9	intact:EBI-21773|uniprotkb:D6VQV7|ensemblfungi:YCL059C	intact:EBI-742740|uniprotkb:Q8IUL5|uniprotkb:Q8IWR9|uniprotkb:Q8N2Y5|uniprotkb:Q96BX0|ensembl:ENSP00000362609	psi-mi:krr1_yeast(display_long)|uniprotkb:KRR1(gene name)|psi-mi:KRR1(display_short)|uniprotkb:KRR-R motif-containing protein 1(gene name synonym)|uniprotkb:Ribosomal RNA assembly protein KRR1(gene name synonym)|uniprotkb:YCL59C(orf name)|uniprotkb:YCL059C(locus name)	psi-mi:zbt8a_human(display_long)|uniprotkb:ZBTB8A(gene name)|psi-mi:ZBTB8A(display_short)|uniprotkb:BOZF1(gene name synonym)|uniprotkb:BTB/POZ and zinc-finger domain-containing factor(gene name synonym)|uniprotkb:BTB/POZ and zinc-finger domains factor on chromosome 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11540035|imex:IM-24995-1860	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009872.1|sgd:S000000564|mint:P25586|dip:DIP-1408N|ensemblfungi:YCL059C_mRNA(transcript)|go:"GO:0000447"("endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0030686"(90S preribosome)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0032040"(small-subunit processome)|go:"GO:0042274"(ribosomal small subunit biogenesis)|interpro:IPR004087(K Homology)|interpro:IPR024166|interpro:IPR036612|interpro:IPR041174|rcsb pdb:4QMF|rcsb pdb:5WLC|rcsb pdb:5WYJ|rcsb pdb:5WYK|rcsb pdb:6KE6|rcsb pdb:6LQP|rcsb pdb:6LQQ|rcsb pdb:6LQU|rcsb pdb:6ZQA|rcsb pdb:6ZQB|rcsb pdb:6ZQC|rcsb pdb:7AJT|reactome:R-SCE-6791226|ensemblfungi:YCL059C(gene)|sgd:YCL059C(identity)	ensembl:ENSG00000160062(gene)|ensembl:ENST00000373510(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|refseq:NP_001035531.2|refseq:NP_001278425.1|entrezgene/locuslink:653121(identity)	-	crc64:7A7F964E2C7FD056	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:wveCX/DmVjCNLOIejb/nWbrbX3o559292	rogid:tsrPT2tHvuBryODKgRXnceXz9s09606	intact-crc:94AB7DDDE16A49AB|rigid:14DucJA9ZMk13aDdze4XbiwfpgU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P25586	uniprotkb:O95751	intact:EBI-21773|uniprotkb:D6VQV7|ensemblfungi:YCL059C	intact:EBI-740738|ensembl:ENSP00000359557|uniprotkb:Q6IAR6	psi-mi:krr1_yeast(display_long)|uniprotkb:KRR1(gene name)|psi-mi:KRR1(display_short)|uniprotkb:KRR-R motif-containing protein 1(gene name synonym)|uniprotkb:Ribosomal RNA assembly protein KRR1(gene name synonym)|uniprotkb:YCL59C(orf name)|uniprotkb:YCL059C(locus name)	psi-mi:ldoc1_human(display_long)|uniprotkb:Leucine zipper protein down-regulated in cancer cells(gene name synonym)|uniprotkb:LDOC1(gene name)|psi-mi:LDOC1(display_short)|uniprotkb:BCUR1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11540026|imex:IM-24995-1859	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009872.1|sgd:S000000564|mint:P25586|dip:DIP-1408N|ensemblfungi:YCL059C_mRNA(transcript)|go:"GO:0000447"("endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0030686"(90S preribosome)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0032040"(small-subunit processome)|go:"GO:0042274"(ribosomal small subunit biogenesis)|interpro:IPR004087(K Homology)|interpro:IPR024166|interpro:IPR036612|interpro:IPR041174|rcsb pdb:4QMF|rcsb pdb:5WLC|rcsb pdb:5WYJ|rcsb pdb:5WYK|rcsb pdb:6KE6|rcsb pdb:6LQP|rcsb pdb:6LQQ|rcsb pdb:6LQU|rcsb pdb:6ZQA|rcsb pdb:6ZQB|rcsb pdb:6ZQC|rcsb pdb:7AJT|reactome:R-SCE-6791226|ensemblfungi:YCL059C(gene)|sgd:YCL059C(identity)	refseq:NP_036449.1|ensembl:ENSG00000182195(gene)|ensembl:ENST00000370526(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071225"(cellular response to muramyl dipeptide)|interpro:IPR032549|interpro:IPR032567|entrezgene/locuslink:23641(identity)	-	crc64:7A7F964E2C7FD056	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:wveCX/DmVjCNLOIejb/nWbrbX3o559292	rogid:Ediu0oNiZ/+YVY8l3fNdgP5A+v09606	intact-crc:8DE453E3568DFB3B|rigid:Fb8dyjYSS1xcF+wKlzG0bFqw6nQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P25566	uniprotkb:Q93062-3	intact:EBI-21713|uniprotkb:D6VQY2|ensemblfungi:YCL033C	intact:EBI-740343|ensembl:ENSP00000340176	psi-mi:mxr2_yeast(display_long)|uniprotkb:YCL033C(locus name)|uniprotkb:YCL33C(orf name)|uniprotkb:MXR2(gene name)|psi-mi:MXR2(display_short)|uniprotkb:MSRB(gene name synonym)	psi-mi:q93062-3(display_long)|uniprotkb:RBPMS(gene name)|psi-mi:RBPMS(display_short)|uniprotkb:HERMES(gene name synonym)|uniprotkb:Heart and RRM expressed sequence(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11540017|imex:IM-24995-1858	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009897.1|sgd:S000000538|dip:DIP-4861N|ensemblfungi:YCL033C(gene)|ensemblfungi:YCL033C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0030091"(protein repair)|go:"GO:0033743"("peptide-methionine (R)-S-oxide reductase activity")|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0046872"(metal ion binding)|interpro:IPR002579(Methionine sulphoxide reductase B)|interpro:IPR011057(Mss4-like)|interpro:IPR028427|sgd:YCL033C(identity)	intact:EBI-740322(rbpms_human)|uniprotkb:Q93062-3(isoform-parent)|ensembl:ENSG00000157110(gene)|ensembl:ENST00000339877(transcript)|entrezgene/locuslink:11030(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:iqa3p6vw9Ah3pxugESw1TdFd6bU559292	rogid:nlPMQAJoKEbPYBwsL3xodmCKd7c9606	intact-crc:D8EC3726B5FA9237|rigid:tiFI/MCyj+mCRyIppJ+RuLF762E	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8N9N5-2	uniprotkb:P25566	intact:EBI-11524452|ensembl:ENSP00000347125	intact:EBI-21713|uniprotkb:D6VQY2|ensemblfungi:YCL033C	psi-mi:q8n9n5-2(display_long)|uniprotkb:BANP(gene name)|psi-mi:BANP(display_short)|uniprotkb:BEN domain-containing protein 1(gene name synonym)|uniprotkb:BEND1(gene name synonym)|uniprotkb:Btg3-associated nuclear protein(gene name synonym)|uniprotkb:SMAR1(gene name synonym)|uniprotkb:Scaffold/matrix-associated region-1-binding protein(gene name synonym)	psi-mi:mxr2_yeast(display_long)|uniprotkb:YCL033C(locus name)|uniprotkb:YCL33C(orf name)|uniprotkb:MXR2(gene name)|psi-mi:MXR2(display_short)|uniprotkb:MSRB(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11540008|imex:IM-24995-1857	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000172530(gene)|ensembl:ENST00000355022(transcript)|intact:EBI-744695(isoform-parent)|uniprotkb:Q8N9N5-2(isoform-parent)|entrezgene/locuslink:54971(identity)	refseq:NP_009897.1|sgd:S000000538|dip:DIP-4861N|ensemblfungi:YCL033C(gene)|ensemblfungi:YCL033C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0030091"(protein repair)|go:"GO:0033743"("peptide-methionine (R)-S-oxide reductase activity")|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0046872"(metal ion binding)|interpro:IPR002579(Methionine sulphoxide reductase B)|interpro:IPR011057(Mss4-like)|interpro:IPR028427|sgd:YCL033C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:ESe6iCAhvq+i57fQHz3rGyg6UOo9606	rogid:iqa3p6vw9Ah3pxugESw1TdFd6bU559292	intact-crc:A42808C88C5DD259|rigid:QDKId1BrMktzR5nKsR1jWENa2Lk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P25635	uniprotkb:O00635	intact:EBI-14332|uniprotkb:P25633|uniprotkb:P25636|uniprotkb:D6VR63|ensemblfungi:YCR057C	intact:EBI-2130415|uniprotkb:B2R862|ensembl:ENSP00000349596	psi-mi:pwp2_yeast(display_long)|uniprotkb:PWP2(gene name)|psi-mi:PWP2(display_short)|uniprotkb:UTP1(gene name synonym)|uniprotkb:YCR057C(locus name)|uniprotkb:YCR55C/YCR57C/YCR58C(orf name)|uniprotkb:U3 small nucleolar RNA-associated protein 1(gene name synonym)|uniprotkb:U three protein 1(gene name synonym)	psi-mi:tri38_human(display_long)|uniprotkb:TRIM38(gene name)|psi-mi:TRIM38(display_short)|uniprotkb:RNF15(gene name synonym)|uniprotkb:RORET(gene name synonym)|uniprotkb:RING finger protein 15(gene name synonym)|uniprotkb:Zinc finger protein RoRet(gene name synonym)|uniprotkb:Tripartite motif-containing protein 38(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM38(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11540080|imex:IM-24995-1865	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0000920"(septum digestion after cytokinesis)|go:"GO:0003729"(mRNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030686"(90S preribosome)|go:"GO:0032040"(small-subunit processome)|go:"GO:0034388"(Pwp2p-containing subcomplex of 90S preribosome)|interpro:IPR001680(WD40 repeat)|interpro:IPR007148(Small-subunit processome, Utp12)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR027145|interpro:IPR036322|rcsb pdb:5I2T|rcsb pdb:5WLC|rcsb pdb:5WYJ|ensemblfungi:YCR057C(gene)|ensemblfungi:YCR057C_mRNA(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0000447"("endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|rcsb pdb:5WYK|go:"GO:0000472"("endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000480"("endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|rcsb pdb:6KE6|rcsb pdb:6LQP|rcsb pdb:6LQQ|rcsb pdb:6LQR|rcsb pdb:6LQS|rcsb pdb:6LQT|rcsb pdb:6LQU|rcsb pdb:6LQV|rcsb pdb:6ND4|rcsb pdb:6ZQA|rcsb pdb:6ZQB|rcsb pdb:6ZQC|rcsb pdb:6ZQD|rcsb pdb:6ZQE|rcsb pdb:6ZQF|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-6791226|refseq:NP_009984.1|sgd:S000000653|mint:P25635|dip:DIP-1868N|sgd:YCR057C(identity)	refseq:NP_006346.1|refseq:XP_005248856.1|refseq:XP_005248857.1|ensembl:ENSG00000112343(gene)|ensembl:ENST00000357085(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046598"(positive regulation of viral entry into host cell)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR035790|interpro:IPR043136|reactome:R-HSA-877300|entrezgene/locuslink:10475(identity)	-	crc64:CBEE4720F81378B6	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:3JKhaE50yPlCymnkEC14JB9atNY559292	rogid:Zh4X/6v/qKZlDkMV6hhn7OsvPnQ9606	intact-crc:FB157A7F358E13EE|rigid:5UniEi26OZCrhkjs49PI/+pPHEk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8TBB1	uniprotkb:P25631	intact:EBI-739832|uniprotkb:Q4W5K7|uniprotkb:Q8N4C2|uniprotkb:Q96MJ7|uniprotkb:Q9BY20|ensembl:ENSP00000263925	intact:EBI-2347265|uniprotkb:D6VR59|ensemblfungi:YCR051W	psi-mi:lnx1_human(display_long)|uniprotkb:LNX1(gene name)|psi-mi:LNX1(display_short)|uniprotkb:LNX(gene name synonym)|uniprotkb:Numb-binding protein 1(gene name synonym)|uniprotkb:Ligand of Numb-protein X 1(gene name synonym)|uniprotkb:PDZ domain-containing RING finger protein 2(gene name synonym)|uniprotkb:PDZRN2(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase LNX(gene name synonym)|uniprotkb:UNQ574/PRO1136(orf name)	psi-mi:ycu1_yeast(display_long)|uniprotkb:YCR51W(orf name)|uniprotkb:YCR051W(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11540071|imex:IM-24995-1864	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001119800.1|refseq:NP_116011.2|refseq:XP_005265842.1|refseq:XP_016864265.1|ensembl:ENSG00000072201(gene)|ensembl:ENST00000263925(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR036034|mint:Q8TBB1|rcsb pdb:3B76|rcsb pdb:5H7R|rcsb pdb:5H7S|reactome:R-HSA-983168|entrezgene/locuslink:84708(identity)	refseq:NP_009980.1|sgd:S000000647|interpro:IPR002110(Ankyrin)|interpro:IPR036770|ensemblfungi:YCR051W(gene)|ensemblfungi:YCR051W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|sgd:YCR051W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:tWvePnVxh9yxWl8nQd3KZhCSKKo9606	rogid:xSvXYNOUhBZjJgwGzwJ+muPq8tU559292	intact-crc:EB4F79E7FB492C61|rigid:/Yna5fluuFNb50rujtP1z/VIRlM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P25631	uniprotkb:O14874	intact:EBI-2347265|uniprotkb:D6VR59|ensemblfungi:YCR051W	intact:EBI-1046765|uniprotkb:Q96IN5|uniprotkb:Q6FGL4|intact:EBI-1210327|uniprotkb:A8MY43|uniprotkb:Q96G95|ensembl:ENSP00000219794|ensembl:ENSP00000378405	psi-mi:ycu1_yeast(display_long)|uniprotkb:YCR51W(orf name)|uniprotkb:YCR051W(locus name)	psi-mi:bckd_human(display_long)|uniprotkb:Branched-chain alpha-ketoacid dehydrogenase kinase(gene name synonym)|uniprotkb:BCKDK(gene name)|psi-mi:BCKDK(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11540062|imex:IM-24995-1863	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009980.1|sgd:S000000647|interpro:IPR002110(Ankyrin)|interpro:IPR036770|ensemblfungi:YCR051W(gene)|ensemblfungi:YCR051W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|sgd:YCR051W(identity)	refseq:NP_005872.2|go:"GO:0005947"(mitochondrial alpha-ketoglutarate dehydrogenase complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006550"(isoleucine catabolic process)|go:"GO:0006552"(leucine catabolic process)|go:"GO:0006574"(valine catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009063"(cellular amino acid catabolic process)|go:"GO:0009083"(branched-chain amino acid catabolic process)|go:"GO:0010906"(regulation of glucose metabolic process)|go:"GO:0016301"(kinase activity)|go:"GO:0016310"(phosphorylation)|go:"GO:0045763"(negative regulation of cellular amino acid metabolic process)|go:"GO:0047323"("[3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring)] kinase activity")|interpro:IPR003594(ATP-binding region, ATPase-like)|refseq:NP_001116429.1|refseq:NP_001258855.1|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR018955|go:"GO:0005759"(mitochondrial matrix)|interpro:IPR036784|interpro:IPR036890|interpro:IPR039028|mint:O14874|reactome:R-HSA-70895|ensembl:ENSG00000103507(gene)|ensembl:ENST00000219794(transcript)|ensembl:ENST00000394951(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004740"("pyruvate dehydrogenase (acetyl-transferring) kinase activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|entrezgene/locuslink:10295(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:xSvXYNOUhBZjJgwGzwJ+muPq8tU559292	rogid:0hiSb7/qtSPoHt/cmLnUo7Gq6OI9606	intact-crc:F6062724EC2080D0|rigid:yZ1XK5JunV7csCewqliY0rXO2FY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96BA8	uniprotkb:P25619	intact:EBI-6942903|ensembl:ENSP00000481956|intact:MINT-268046|intact:MINT-8162577|uniprotkb:Q8N2D5|uniprotkb:Q96CP0	intact:EBI-8563|uniprotkb:Q04556|uniprotkb:D6VR31|ensemblfungi:YCR021C	psi-mi:cr3l1_human(display_long)|uniprotkb:CREB3L1(gene name)|psi-mi:CREB3L1(display_short)|uniprotkb:OASIS(gene name synonym)|uniprotkb:PSEC0238(orf name)|uniprotkb:Old astrocyte specifically-induced substance(gene name synonym)	psi-mi:hsp30_yeast(display_long)|uniprotkb:YCR21C(orf name)|uniprotkb:YCR021C(locus name)|uniprotkb:HSP30(gene name)|psi-mi:HSP30(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11540053|imex:IM-24995-1862	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157613(gene)|ensembl:ENST00000621158(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0070278"(extracellular matrix constituent secretion)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029805|mint:Q96BA8|reactome:R-HSA-8874211|refseq:NP_443086.1|entrezgene/locuslink:90993(identity)	refseq:NP_009950.1|sgd:S000000615|mint:P25619|dip:DIP-4586N|ensemblfungi:YCR021C(gene)|ensemblfungi:YCR021C_mRNA(transcript)|go:"GO:0005216"(ion channel activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0034605"(cellular response to heat)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0071470"(cellular response to osmotic stress)|interpro:IPR001425(Rhodopsin, bacterial)|interpro:IPR043476|sgd:YCR021C(identity)	-	comment:mint|function:"Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE"	crc64:260474A481D29AC5	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:sMWUFmBeBBCO+T0Y2CuB/un1lBg9606	rogid:hkFai3t0xeh5wGaj/RAYUfPwoPw559292	intact-crc:163C1D52C96776D4|rigid:67qn36GAPcksjVg01uLfF9E88fk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P25638	uniprotkb:P24278	intact:EBI-21956|uniprotkb:D6VR65|ensemblfungi:YCR060W	intact:EBI-739899|uniprotkb:Q8IYH9|uniprotkb:B3KUX6|ensembl:ENSP00000378204|ensembl:ENSP00000476746	psi-mi:tah1_yeast(display_long)|uniprotkb:YCR60W(orf name)|uniprotkb:YCR060W(locus name)|uniprotkb:TAH1(gene name)|psi-mi:TAH1(display_short)	psi-mi:zbt25_human(display_long)|uniprotkb:ZBTB25(gene name)|psi-mi:ZBTB25(display_short)|uniprotkb:KUP(gene name synonym)|uniprotkb:ZNF46(gene name synonym)|uniprotkb:Zinc finger protein 46(gene name synonym)|uniprotkb:Zinc finger protein KUP(gene name synonym)|uniprotkb:C14orf51(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11540118|imex:IM-24995-1869	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009986.1|sgd:S000000656|mint:P25638|dip:DIP-5000N|ensemblfungi:YCR060W(gene)|ensemblfungi:YCR060W_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|go:"GO:0051087"(chaperone binding)|go:"GO:0097255"(R2TP complex)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|rcsb pdb:2L6J|rcsb pdb:2LSU|rcsb pdb:2LSV|rcsb pdb:2MNJ|rcsb pdb:4CGQ|rcsb pdb:4CGU|sgd:YCR060W(identity)	refseq:NP_008908.2|ensembl:ENSG00000089775(gene)|ensembl:ENST00000394715(transcript)|ensembl:ENST00000608382(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:P24278|refseq:NP_001291436.1|refseq:XP_011535445.1|refseq:XP_006720314.1|refseq:XP_006720315.1|refseq:XP_016877121.1|refseq:XP_016877122.1|refseq:XP_016877123.1|refseq:XP_016877124.1|entrezgene/locuslink:7597(identity)	-	crc64:3738DE6F227F803A	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:DXXWcBPtKzTtK2Hp7l4g0ukIZPQ559292	rogid:xi3bM5CoeXvVZNBOzaQlZdWU4ag9606	intact-crc:2D19C4A50611C299|rigid:gnRe71VsITlsLNC5wTF4zzIJG8s	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96HT8	uniprotkb:P25637	intact:EBI-748896|uniprotkb:Q6NXT8|uniprotkb:Q9P0J5|uniprotkb:B2R6R0|ensembl:ENSP00000318154	intact:EBI-21951|uniprotkb:D6VR64|ensemblfungi:YCR059C	psi-mi:mr1l1_human(display_long)|uniprotkb:PP784(orf name)|uniprotkb:MRFAP1L1(gene name)|psi-mi:MRFAP1L1(display_short)	psi-mi:yih1_yeast(display_long)|uniprotkb:YCR59C(orf name)|uniprotkb:YCR059C(locus name)|uniprotkb:YIH1(gene name)|psi-mi:YIH1(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11540109|imex:IM-24995-1868	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_982287.1|refseq:XP_005247989.1|ensembl:ENSG00000178988(gene)|ensembl:ENST00000320848(transcript)|go:"GO:0042802"(identical protein binding)|interpro:IPR029254|mint:Q96HT8|dip:DIP-29019N|entrezgene/locuslink:114932(identity)	refseq:NP_009985.1|sgd:S000000655|mint:P25637|dip:DIP-1846N|ensemblfungi:YCR059C(gene)|ensemblfungi:YCR059C_mRNA(transcript)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0003785"(actin monomer binding)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0033673"(negative regulation of kinase activity)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0043022"(ribosome binding)|go:"GO:0140469"(GCN2-mediated signaling)|go:"GO:1905538"(polysome binding)|interpro:IPR001498(Protein of unknown function UPF0029, N-terminal)|interpro:IPR006575(RWD)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR020568|interpro:IPR020569|interpro:IPR023582|interpro:IPR036956|rcsb pdb:6BQI|rcsb pdb:6U1L|rcsb pdb:6U1O|sgd:YCR059C(identity)	-	caution:This sequence has been withdrawn from Uniprot.|crc64:6C914B0B4BEECAE5	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:hb4enqSS7DeieOByDoLDkXkSlIk9606	rogid:aAbGir3o4M0LUpwOv6YBC25KpQQ559292	intact-crc:644BCCC8208274C9|rigid:DmLeJugk9z8HWbVTC4xBweyUnV0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8N4C7	uniprotkb:P25635	intact:EBI-8484990|intact:MINT-6940674|ensembl:ENSP00000320679	intact:EBI-14332|uniprotkb:P25633|uniprotkb:P25636|uniprotkb:D6VR63|ensemblfungi:YCR057C	psi-mi:stx19_human(display_long)|uniprotkb:STX19(gene name)|psi-mi:STX19(display_short)	psi-mi:pwp2_yeast(display_long)|uniprotkb:PWP2(gene name)|psi-mi:PWP2(display_short)|uniprotkb:UTP1(gene name synonym)|uniprotkb:YCR057C(locus name)|uniprotkb:YCR55C/YCR57C/YCR58C(orf name)|uniprotkb:U3 small nucleolar RNA-associated protein 1(gene name synonym)|uniprotkb:U three protein 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11540100|imex:IM-24995-1867	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011511144.1|refseq:NP_001001850.1|ensembl:ENSG00000178750(gene)|ensembl:ENST00000315099(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006887"(exocytosis)|go:"GO:0006906"(vesicle fusion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0048278"(vesicle docking)|go:"GO:0048787"(presynaptic active zone membrane)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006011(Syntaxin, N-terminal)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|interpro:IPR015708(Syntaxin-3)|mint:Q8N4C7|entrezgene/locuslink:415117(identity)	go:"GO:0000920"(septum digestion after cytokinesis)|go:"GO:0003729"(mRNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030686"(90S preribosome)|go:"GO:0032040"(small-subunit processome)|go:"GO:0034388"(Pwp2p-containing subcomplex of 90S preribosome)|interpro:IPR001680(WD40 repeat)|interpro:IPR007148(Small-subunit processome, Utp12)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR027145|interpro:IPR036322|rcsb pdb:5I2T|rcsb pdb:5WLC|rcsb pdb:5WYJ|ensemblfungi:YCR057C(gene)|ensemblfungi:YCR057C_mRNA(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0000447"("endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|rcsb pdb:5WYK|go:"GO:0000472"("endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000480"("endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|rcsb pdb:6KE6|rcsb pdb:6LQP|rcsb pdb:6LQQ|rcsb pdb:6LQR|rcsb pdb:6LQS|rcsb pdb:6LQT|rcsb pdb:6LQU|rcsb pdb:6LQV|rcsb pdb:6ND4|rcsb pdb:6ZQA|rcsb pdb:6ZQB|rcsb pdb:6ZQC|rcsb pdb:6ZQD|rcsb pdb:6ZQE|rcsb pdb:6ZQF|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-6791226|refseq:NP_009984.1|sgd:S000000653|mint:P25635|dip:DIP-1868N|sgd:YCR057C(identity)	-	comment:mint|comment:homomint	crc64:CBEE4720F81378B6	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:FNBoXbeKnFcWR1+dwnaJVvWJ23c9606	rogid:3JKhaE50yPlCymnkEC14JB9atNY559292	intact-crc:B88248D72B68E563|rigid:8Xnxl0XOXaN/+rHr2sdkkqDMemY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q2NKX8	uniprotkb:P25635	intact:EBI-1042535|uniprotkb:Q8NCI1|uniprotkb:Q96H93|uniprotkb:Q9NXQ8|intact:EBI-2560904|ensembl:ENSP00000334675	intact:EBI-14332|uniprotkb:P25633|uniprotkb:P25636|uniprotkb:D6VR63|ensemblfungi:YCR057C	psi-mi:erc6l_human(display_long)|uniprotkb:ERCC6L(gene name)|psi-mi:ERCC6L(display_short)|uniprotkb:PICH(gene name synonym)|uniprotkb:ATP-dependent helicase ERCC6-like(gene name synonym)|uniprotkb:PLK1-interacting checkpoint helicase(gene name synonym)|uniprotkb:Tumor antigen BJ-HCC-15(gene name synonym)	psi-mi:pwp2_yeast(display_long)|uniprotkb:PWP2(gene name)|psi-mi:PWP2(display_short)|uniprotkb:UTP1(gene name synonym)|uniprotkb:YCR057C(locus name)|uniprotkb:YCR55C/YCR57C/YCR58C(orf name)|uniprotkb:U3 small nucleolar RNA-associated protein 1(gene name synonym)|uniprotkb:U three protein 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11540089|imex:IM-24995-1866	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060139.2|ensembl:ENSG00000186871(gene)|ensembl:ENST00000334463(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0015616"(DNA translocase activity)|go:"GO:0016020"(membrane)|go:"GO:0051301"(cell division)|go:"GO:0070615"|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000330(SNF2-related)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR038718|rcsb pdb:5JNO|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|entrezgene/locuslink:54821(identity)	go:"GO:0000920"(septum digestion after cytokinesis)|go:"GO:0003729"(mRNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030686"(90S preribosome)|go:"GO:0032040"(small-subunit processome)|go:"GO:0034388"(Pwp2p-containing subcomplex of 90S preribosome)|interpro:IPR001680(WD40 repeat)|interpro:IPR007148(Small-subunit processome, Utp12)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR027145|interpro:IPR036322|rcsb pdb:5I2T|rcsb pdb:5WLC|rcsb pdb:5WYJ|ensemblfungi:YCR057C(gene)|ensemblfungi:YCR057C_mRNA(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0000447"("endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|rcsb pdb:5WYK|go:"GO:0000472"("endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000480"("endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|rcsb pdb:6KE6|rcsb pdb:6LQP|rcsb pdb:6LQQ|rcsb pdb:6LQR|rcsb pdb:6LQS|rcsb pdb:6LQT|rcsb pdb:6LQU|rcsb pdb:6LQV|rcsb pdb:6ND4|rcsb pdb:6ZQA|rcsb pdb:6ZQB|rcsb pdb:6ZQC|rcsb pdb:6ZQD|rcsb pdb:6ZQE|rcsb pdb:6ZQF|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-6791226|refseq:NP_009984.1|sgd:S000000653|mint:P25635|dip:DIP-1868N|sgd:YCR057C(identity)	-	-	crc64:CBEE4720F81378B6	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:3HZtZq9pgDyQB+UcxtAQjHv7+7o9606	rogid:3JKhaE50yPlCymnkEC14JB9atNY559292	intact-crc:6494CB80A6A5B3BA|rigid:Lg3oW65HHrRjOLx+yUC5fbxZUKk	false	sufficient binding region:832-1250	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P26343	uniprotkb:Q13643	intact:EBI-5489|uniprotkb:D6VX97|ensemblfungi:YKR034W	intact:EBI-741101|ensembl:ENSP00000362107|uniprotkb:Q6I9T0|uniprotkb:Q9BVA2|uniprotkb:D3DPT6	psi-mi:dal80_yeast(display_long)|uniprotkb:YKR034W(locus name)|uniprotkb:DAL80(gene name)|psi-mi:DAL80(display_short)|uniprotkb:UGA43(gene name synonym)|uniprotkb:Regulatory protein UGA43(gene name synonym)	psi-mi:fhl3_human(display_long)|uniprotkb:FHL3(gene name)|psi-mi:FHL3(display_short)|uniprotkb:SLIM2(gene name synonym)|uniprotkb:Skeletal muscle LIM-protein 2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11540165|imex:IM-24995-1874	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012959.1|sgd:S000001742|dip:DIP-2094N|ensemblfungi:YKR034W(gene)|ensemblfungi:YKR034W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042128"(nitrate assimilation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0090295"(nitrogen catabolite repression of transcription)|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR039355|sgd:YKR034W(identity)	refseq:NP_004459.2|ensembl:ENSG00000183386(gene)|ensembl:ENST00000373016(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005925"(focal adhesion)|go:"GO:0007517"(muscle organ development)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0046872"(metal ion binding)|interpro:IPR001781(Zinc finger, LIM-type)|mint:Q13643|rcsb pdb:1WYH|rcsb pdb:2CUQ|rcsb pdb:2EHE|interpro:IPR037987|refseq:NP_001230807.1|dip:DIP-42030N|entrezgene/locuslink:2275(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Qfoc7DZ+/Nwthc4Hf93+iwuYgVg559292	rogid:RAo+b/VgFSnHSbgR+zXuxJvypxM9606	intact-crc:F8C0E72BEBCE07BA|rigid:OUrGCbGSLz09l+RBSshd6fA3siM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P26343	uniprotkb:Q08379	intact:EBI-5489|uniprotkb:D6VX97|ensemblfungi:YKR034W	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	psi-mi:dal80_yeast(display_long)|uniprotkb:YKR034W(locus name)|uniprotkb:DAL80(gene name)|psi-mi:DAL80(display_short)|uniprotkb:UGA43(gene name synonym)|uniprotkb:Regulatory protein UGA43(gene name synonym)	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11540154|imex:IM-24995-1873	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012959.1|sgd:S000001742|dip:DIP-2094N|ensemblfungi:YKR034W(gene)|ensemblfungi:YKR034W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042128"(nitrate assimilation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0090295"(nitrogen catabolite repression of transcription)|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR039355|sgd:YKR034W(identity)	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N|entrezgene/locuslink:2801(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2017/05/26	rogid:Qfoc7DZ+/Nwthc4Hf93+iwuYgVg559292	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	intact-crc:A50B2C4C3ABCA30F|rigid:/MJXVD3xlFybQYVPoql6KjIiCSY	false	-	sufficient binding region:383-1002	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q969F0	uniprotkb:P25656	intact:EBI-743099|ensembl:ENSP00000359375	intact:EBI-22014|uniprotkb:D6VR94|ensemblfungi:YCR094W	psi-mi:fate1_human(display_long)|uniprotkb:Tumor antigen BJ-HCC-2(gene name synonym)|uniprotkb:Cancer/testis antigen 43(gene name synonym)|uniprotkb:FATE1(gene name)|psi-mi:FATE1(display_short)|uniprotkb:FATE(gene name synonym)	psi-mi:cdc50_yeast(display_long)|uniprotkb:YCR94W(orf name)|uniprotkb:YCR094W(locus name)|uniprotkb:CDC50(gene name)|psi-mi:CDC50(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11540145|imex:IM-24995-1872	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_149076.1|ensembl:ENSG00000147378(gene)|ensembl:ENST00000370350(transcript)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|go:"GO:0051562"(negative regulation of mitochondrial calcium ion concentration)|interpro:IPR039153|interpro:IPR039433|mint:Q969F0|entrezgene/locuslink:89885(identity)	refseq:NP_010018.1|sgd:S000000690|dip:DIP-5138N|ensemblfungi:YCR094W(gene)|ensemblfungi:YCR094W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006897"(endocytosis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0045332"(phospholipid translocation)|go:"GO:0051666"(actin cortical patch localization)|go:"GO:0140331"(aminophospholipid translocation)|go:"GO:1990530"(Cdc50p-Drs2p complex)|interpro:IPR005045(Protein of unknown function DUF284, transmembrane eukaryotic)|rcsb pdb:6PSY|rcsb pdb:6ROH|rcsb pdb:6ROI|rcsb pdb:6ROJ|rcsb pdb:7OH4|rcsb pdb:7OH6|rcsb pdb:7OH7|reactome:R-SCE-6798695|rcsb pdb:6PSX|mint:P25656|sgd:YCR094W(identity)	-	-	crc64:565575CA402C0C91	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Nm1N6lO92MHr5rIKC007oouF5RE9606	rogid:zVi09MNh1hpBUuc5AzasxmCrnKY559292	intact-crc:E74FB812E8155785|rigid:Wvf8VIUEVahkuI+cHqFOqMHyVSU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9BQY9-2	uniprotkb:P25651	intact:EBI-11524759|ensembl:ENSP00000349822|ensembl:ENSP00000354250|ensembl:ENSP00000361795|ensembl:ENSP00000361797|ensembl:ENSP00000361808	intact:EBI-22001|uniprotkb:D6VR86|ensemblfungi:YCR086W	psi-mi:q9bqy9-2(display_long)|uniprotkb:DBNDD2(gene name)|psi-mi:DBNDD2(display_short)|uniprotkb:C20orf35(gene name synonym)|uniprotkb:Casein kinase-1 binding protein(gene name synonym)|uniprotkb:HSMNP1(gene name synonym)	psi-mi:csm1_yeast(display_long)|uniprotkb:YCR086W(locus name)|uniprotkb:YCR86W(orf name)|uniprotkb:Chromosome segregation in meiosis protein 1(gene name synonym)|uniprotkb:CSM1(gene name)|psi-mi:CSM1(display_short)|uniprotkb:SPO86(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11540136|imex:IM-24995-1871	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-747462(isoform-parent)|ensembl:ENSG00000244274(gene)|ensembl:ENST00000357275(transcript)|ensembl:ENST00000360981(transcript)|ensembl:ENST00000372710(transcript)|ensembl:ENST00000372712(transcript)|ensembl:ENST00000372723(transcript)|entrezgene/locuslink:55861(identity)	refseq:NP_010009.1|sgd:S000000682|dip:DIP-1283N|ensemblfungi:YCR086W(gene)|ensemblfungi:YCR086W_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005730"(nucleolus)|go:"GO:0033551"(monopolin complex)|go:"GO:0034503"(protein localization to nucleolar rDNA repeats)|go:"GO:0034506"(chromosome, centromeric core domain)|go:"GO:0042802"(identical protein binding)|go:"GO:0045132"(meiotic chromosome segregation)|go:"GO:0045143"(homologous chromosome segregation)|go:"GO:0045144"(meiotic sister chromatid segregation)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051455"(monopolar spindle attachment to meiosis I kinetochore)|go:"GO:0070550"(rDNA condensation)|go:"GO:0072686"(mitotic spindle)|go:"GO:1990644"(microtubule site clamp)|interpro:IPR020981|interpro:IPR038608|interpro:IPR040349|interpro:IPR041671|rcsb pdb:3N4R|rcsb pdb:3N4S|rcsb pdb:3N4X|rcsb pdb:3N7N|rcsb pdb:5KTB|rcsb pdb:5V1A|rcsb pdb:5V3N|rcsb pdb:6DEI|mint:P25651|sgd:YCR086W(identity)	-	-	crc64:9650E0DA89B31CC5	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:AfeXaSlYyOOp2QaUjv0FRzdfTNY9606	rogid:rN1hGW+i7AN2+SmrIrwqz4ZSbQk559292	intact-crc:C7EAEE98E029F133|rigid:21rU79/LxmF6xVE+3TJFcYKgeYU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P25641	uniprotkb:Q96HH9	intact:EBI-375693|uniprotkb:Q8NIL6|uniprotkb:D6VR71|ensemblfungi:YCR068W	intact:EBI-2832937|uniprotkb:Q9H753|uniprotkb:D3DSZ3|uniprotkb:B7Z1F2|uniprotkb:B7Z3R1|uniprotkb:B7Z6D8|uniprotkb:B7Z8T2|ensembl:ENSP00000285689	psi-mi:atg15_yeast(display_long)|uniprotkb:ATG15(gene name)|psi-mi:ATG15(display_short)|uniprotkb:AUT5(gene name synonym)|uniprotkb:CVT17(gene name synonym)|uniprotkb:YCR068W(locus name)|uniprotkb:YCR68W(orf name)|uniprotkb:Autophagy-related protein 15(gene name synonym)|uniprotkb:Cytoplasm to vacuole targeting protein 17(gene name synonym)	psi-mi:grm2b_human(display_long)|uniprotkb:GRAMD2B(gene name)|psi-mi:GRAMD2B(display_short)|uniprotkb:GRAMD3(gene name synonym)|uniprotkb:HCV NS3-transactivated protein 2(gene name synonym)|uniprotkb:NS3TP2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11540127|imex:IM-24995-1870	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YCR068W_mRNA(transcript)|go:"GO:0000425"(pexophagy)|go:"GO:0004620"(phospholipase activity)|go:"GO:0004806"(triglyceride lipase activity)|go:"GO:0005775"(vacuolar lumen)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006624"(vacuolar protein processing)|go:"GO:0006660"(phosphatidylserine catabolic process)|go:"GO:0006914"(autophagy)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0030397"(membrane disassembly)|go:"GO:0032585"(multivesicular body membrane)|go:"GO:0034496"(multivesicular body membrane disassembly)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0046461"(neutral lipid catabolic process)|interpro:IPR002921(Lipase, class 3)|interpro:IPR029058|ensemblfungi:YCR068W(gene)|refseq:NP_009994.2|sgd:S000000664|dip:DIP-5001N|sgd:YCR068W(identity)	refseq:XP_016865274.1|refseq:NP_001139791.1|refseq:NP_001139792.1|refseq:NP_001139793.1|refseq:NP_001139794.1|refseq:NP_076416.2|refseq:XP_005272120.1|ensembl:ENSG00000155324(gene)|ensembl:ENST00000285689(transcript)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0042802"(identical protein binding)|interpro:IPR004182(GRAM)|interpro:IPR011993(Pleckstrin homology-type)|entrezgene/locuslink:65983(identity)	-	crc64:B56ABAB72B999019	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:ttgDIIQIdYUuP+ME547oz2gZuEA559292	rogid:6UkVJddV5/mHpLX/rk00jMwCA+k9606	intact-crc:09EE49B9E23D5E02|rigid:O18CJOhduXKvpXhJ8XULUTU5KbU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P26448	uniprotkb:O15156-2	intact:EBI-3824|uniprotkb:D6VZN0|ensemblfungi:YMR055C	intact:EBI-11522250|ensembl:ENSP00000406286	psi-mi:bub2_yeast(display_long)|uniprotkb:BUB2(gene name)|psi-mi:BUB2(display_short)|uniprotkb:YMR055C(locus name)|uniprotkb:YM9796.08C(orf name)|uniprotkb:Cell cycle arrest protein BUB2(gene name synonym)	psi-mi:o15156-2(display_long)|uniprotkb:ZBTB7B(gene name)|psi-mi:ZBTB7B(display_short)|uniprotkb:Krueppel-related zinc finger protein cKrox(gene name synonym)|uniprotkb:T-helper-inducing POZ/Krueppel-like factor(gene name synonym)|uniprotkb:ZBTB15(gene name synonym)|uniprotkb:ZFP67(gene name synonym)|uniprotkb:ZNF857B(gene name synonym)|uniprotkb:Zinc finger and BTB domain-containing protein 15(gene name synonym)|uniprotkb:Zinc finger protein 67 homolog(gene name synonym)|uniprotkb:Zinc finger protein 857B(gene name synonym)|uniprotkb:Zinc finger protein Th-POK(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11540195|imex:IM-24995-1877	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013771.1|sgd:S000004659|dip:DIP-1215N|mint:P26448|ensemblfungi:YMR055C(gene)|ensemblfungi:YMR055C_mRNA(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0031030"(negative regulation of septation initiation signaling)|go:"GO:0031578"(mitotic spindle orientation checkpoint signaling)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0051301"(cell division)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:1902543"(negative regulation of protein localization to mitotic spindle pole body)|go:"GO:1990334"(Bfa1-Bub2 complex)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR035969|sgd:YMR055C(identity)	intact:EBI-740434(isoform-parent)|ensembl:ENSG00000160685(gene)|ensembl:ENST00000417934(transcript)|uniprotkb:O15156-2(isoform-parent)|entrezgene/locuslink:51043(identity)	-	crc64:A1DDBFB548E81EA3	isoform-comment:No experimental confirmation available.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:+03m4HOOcKjpSjqpEZ8wCgD2Egc559292	rogid:41NEFYyprTXI+fOHVFh78TPKF289606	intact-crc:CA248A479DD5C22E|rigid:ahVGA7Cxy0MID1b7oFyljnjiRUM	false	-	sufficient binding region:35-573	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P26343	uniprotkb:Q9HCM9-2	intact:EBI-5489|uniprotkb:D6VX97|ensemblfungi:YKR034W	intact:EBI-11523450|ensembl:ENSP00000365847|ensembl:ENSP00000373095|ensembl:ENSP00000373097|ensembl:ENSP00000379797|ensembl:ENSP00000379800|ensembl:ENSP00000383486|ensembl:ENSP00000387445|ensembl:ENSP00000389198|ensembl:ENSP00000389852|ensembl:ENSP00000392130|ensembl:ENSP00000394353|ensembl:ENSP00000396986|ensembl:ENSP00000398956|ensembl:ENSP00000401071|ensembl:ENSP00000401184|ensembl:ENSP00000404340|ensembl:ENSP00000404904|ensembl:ENSP00000411582|ensembl:ENSP00000412743|ensembl:ENSP00000414525|ensembl:ENSP00000415259	psi-mi:dal80_yeast(display_long)|uniprotkb:YKR034W(locus name)|uniprotkb:DAL80(gene name)|psi-mi:DAL80(display_short)|uniprotkb:UGA43(gene name synonym)|uniprotkb:Regulatory protein UGA43(gene name synonym)	psi-mi:q9hcm9-2(display_long)|uniprotkb:TRIM39(gene name)|psi-mi:TRIM39(display_short)|uniprotkb:RING finger protein 23(gene name synonym)|uniprotkb:RNF23(gene name synonym)|uniprotkb:TFP(gene name synonym)|uniprotkb:Testis-abundant finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 39(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM39(gene name synonym)|uniprotkb:TIM39beta(isoform synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11540185|imex:IM-24995-1876	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012959.1|sgd:S000001742|dip:DIP-2094N|ensemblfungi:YKR034W(gene)|ensemblfungi:YKR034W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042128"(nitrate assimilation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0090295"(nitrogen catabolite repression of transcription)|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR039355|sgd:YKR034W(identity)	intact:EBI-739510(isoform-parent)|ensembl:ENSG00000204599(gene)|ensembl:ENSG00000206495(gene)|ensembl:ENSG00000224994(gene)|ensembl:ENSG00000226437(gene)|ensembl:ENSG00000229929(gene)|ensembl:ENSG00000230308(gene)|ensembl:ENSG00000232839(gene)|ensembl:ENST00000376659(transcript)|ensembl:ENST00000383601(transcript)|ensembl:ENST00000383603(transcript)|ensembl:ENST00000396548(transcript)|ensembl:ENST00000396551(transcript)|ensembl:ENST00000400644(transcript)|ensembl:ENST00000414015(transcript)|ensembl:ENST00000419790(transcript)|ensembl:ENST00000430502(transcript)|ensembl:ENST00000431272(transcript)|ensembl:ENST00000433900(transcript)|ensembl:ENST00000438076(transcript)|ensembl:ENST00000438859(transcript)|ensembl:ENST00000440117(transcript)|ensembl:ENST00000443109(transcript)|ensembl:ENST00000446397(transcript)|ensembl:ENST00000449318(transcript)|ensembl:ENST00000450778(transcript)|ensembl:ENST00000451132(transcript)|ensembl:ENST00000452705(transcript)|ensembl:ENST00000458607(transcript)|uniprotkb:Q9HCM9-2(isoform-parent)|entrezgene/locuslink:56658(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Qfoc7DZ+/Nwthc4Hf93+iwuYgVg559292	rogid:UfSn2+IVRxtGomVeDGdZpL7mz5I9606	intact-crc:95F210BFF31B5540|rigid:yi5zVgyt3q9xUyRgtYtQ4W4qgXI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P26343	uniprotkb:Q8IYF3-3	intact:EBI-5489|uniprotkb:D6VX97|ensemblfungi:YKR034W	intact:EBI-11523345|ensembl:ENSP00000363453	psi-mi:dal80_yeast(display_long)|uniprotkb:YKR034W(locus name)|uniprotkb:DAL80(gene name)|psi-mi:DAL80(display_short)|uniprotkb:UGA43(gene name synonym)|uniprotkb:Regulatory protein UGA43(gene name synonym)	psi-mi:q8iyf3-3(display_long)|uniprotkb:TEX11(gene name)|psi-mi:TEX11(display_short)|uniprotkb:Protein ZIP4 homolog(gene name synonym)|uniprotkb:ZIP4(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11540174|imex:IM-24995-1875	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012959.1|sgd:S000001742|dip:DIP-2094N|ensemblfungi:YKR034W(gene)|ensemblfungi:YKR034W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042128"(nitrate assimilation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0090295"(nitrogen catabolite repression of transcription)|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR039355|sgd:YKR034W(identity)	ensembl:ENSG00000120498(gene)|ensembl:ENST00000374333(transcript)|intact:EBI-742397(isoform-parent)|uniprotkb:Q8IYF3-3(isoform-parent)|entrezgene/locuslink:56159(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Qfoc7DZ+/Nwthc4Hf93+iwuYgVg559292	rogid:PUAMFmnm5ZV2rnJ1rhm9ZeRCixg9606	intact-crc:5A0989706FC09850|rigid:1LkqKzGxU6MFIMhwAGfgH8AZjdQ	false	-	sufficient binding region:9-925	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P10644	uniprotkb:P27344	intact:EBI-476431|uniprotkb:Q567S7|uniprotkb:K7ER48|ensembl:ENSP00000351410|ensembl:ENSP00000376475|ensembl:ENSP00000445625|ensembl:ENSP00000464977|ensembl:ENSP00000466459	intact:EBI-6076|uniprotkb:D6VQS3|ensemblfungi:YBR278W	psi-mi:kap0_human(display_long)|uniprotkb:Tissue-specific extinguisher 1(gene name synonym)|uniprotkb:PRKAR1A(gene name)|psi-mi:PRKAR1A(display_short)|uniprotkb:PKR1(gene name synonym)|uniprotkb:PRKAR1(gene name synonym)|uniprotkb:TSE1(gene name synonym)	psi-mi:dpb3_yeast(display_long)|uniprotkb:DPB3(gene name)|psi-mi:DPB3(display_short)|uniprotkb:YBR278W(locus name)|uniprotkb:YBR2015(orf name)|uniprotkb:DNA polymerase II subunit C(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11540242|imex:IM-24995-1882	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002725.1|refseq:NP_997636.1|refseq:NP_997637.1|refseq:XP_011523285.1|refseq:XP_011523286.1|refseq:XP_011523287.1|refseq:NP_001263218.1|refseq:NP_001263219.1|refseq:NP_001265362.1|dip:DIP-34368N|ensembl:ENSG00000108946(gene)|ensembl:ENST00000358598(transcript)|ensembl:ENST00000392711(transcript)|ensembl:ENST00000536854(transcript)|ensembl:ENST00000586397(transcript)|ensembl:ENST00000589228(transcript)|go:"GO:0001707"(mesoderm formation)|go:"GO:0004862"(cAMP-dependent protein kinase inhibitor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005771"(multivesicular body)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005952"(cAMP-dependent protein kinase complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007143"(female meiotic nuclear division)|go:"GO:0008603"(cAMP-dependent protein kinase regulator activity)|go:"GO:0010738"(regulation of protein kinase A signaling)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030552"(cAMP binding)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043949"(regulation of cAMP-mediated signaling)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045835"(negative regulation of meiotic nuclear division)|go:"GO:0046007"(negative regulation of activated T cell proliferation)|go:"GO:0060038"(cardiac muscle cell proliferation)|go:"GO:0097224"(sperm connecting piece)|go:"GO:0097546"(ciliary base)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:2000480"(negative regulation of cAMP-dependent protein kinase activity)|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR003117(cAMP-dependent protein kinase, regulatory subunit, type I/II alpha/beta)|interpro:IPR012198(cAMP-dependent protein kinase regulatory subunit)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR018488|rcsb pdb:5KJZ|reactome:R-HSA-163615|reactome:R-HSA-164378|reactome:R-HSA-180024|reactome:R-HSA-381676|reactome:R-HSA-432040|reactome:R-HSA-442720|reactome:R-HSA-5610787|reactome:R-HSA-9660821|reactome:R-HSA-9664323|reactome:R-HSA-983231|interpro:IPR018490|mint:P10644|rcsb pdb:5KJX|rcsb pdb:5KJY|entrezgene/locuslink:5573(identity)	refseq:NP_009837.1|sgd:S000000482|dip:DIP-4803N|mint:P27344|ensemblfungi:YBR278W(gene)|ensemblfungi:YBR278W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006272"(leading strand elongation)|go:"GO:0008622"(epsilon DNA polymerase complex)|go:"GO:0008623"(CHRAC)|go:"GO:0042276"(error-prone translesion synthesis)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0070868"(obsolete heterochromatin organization involved in chromatin silencing)|go:"GO:0090305"(nucleic acid phosphodiester bond hydrolysis)|interpro:IPR009072(Histone-fold)|rcsb pdb:6WJV|reactome:R-SCE-5656169|reactome:R-SCE-6782135|reactome:R-SCE-68952|reactome:R-SCE-68962|sgd:YBR278W(identity)	-	-	crc64:288913917D49C7F9	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:dUZaCJQnC0KZEG4pccIqoT066VY9606	rogid:vWWMmgZ4w7G1VF2V2TDY8cZpKas559292	intact-crc:5CB3D5EF0C07DF48|rigid:DsFGaxwbG19Q0h9U1iDVuL5sUZw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P26448	uniprotkb:Q96AA8	intact:EBI-3824|uniprotkb:D6VZN0|ensemblfungi:YMR055C	intact:EBI-752007|uniprotkb:O60302|uniprotkb:B4DSG0|uniprotkb:A4ZZA7|uniprotkb:Q548S1|uniprotkb:A8K5G5|uniprotkb:G5E9Y0|ensembl:ENSP00000265272	psi-mi:bub2_yeast(display_long)|uniprotkb:BUB2(gene name)|psi-mi:BUB2(display_short)|uniprotkb:YMR055C(locus name)|uniprotkb:YM9796.08C(orf name)|uniprotkb:Cell cycle arrest protein BUB2(gene name synonym)	psi-mi:jkip2_human(display_long)|uniprotkb:JAMIP2(gene name synonym)|uniprotkb:NECC1(gene name synonym)|uniprotkb:Neuroendocrine long coiled-coil protein 1(gene name synonym)|uniprotkb:CTCL tumor antigen HD-CL-04(gene name synonym)|uniprotkb:JAKMIP2(gene name)|psi-mi:JAKMIP2(display_short)|uniprotkb:KIAA0555(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11540233|imex:IM-24995-1881	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013771.1|sgd:S000004659|dip:DIP-1215N|mint:P26448|ensemblfungi:YMR055C(gene)|ensemblfungi:YMR055C_mRNA(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0031030"(negative regulation of septation initiation signaling)|go:"GO:0031578"(mitotic spindle orientation checkpoint signaling)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0051301"(cell division)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:1902543"(negative regulation of protein localization to mitotic spindle pole body)|go:"GO:1990334"(Bfa1-Bub2 complex)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR035969|sgd:YMR055C(identity)	refseq:NP_055605.2|refseq:NP_001257870.1|refseq:NP_001257863.1|refseq:NP_001269211.1|refseq:XP_016865586.1|ensembl:ENSG00000176049(gene)|ensembl:ENST00000265272(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0008017"(microtubule binding)|go:"GO:0019900"(kinase binding)|interpro:IPR024836|interpro:IPR031994|entrezgene/locuslink:9832(identity)	-	crc64:A1DDBFB548E81EA3	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:+03m4HOOcKjpSjqpEZ8wCgD2Egc559292	rogid:WnaHkeDBQXut9F9AzzaCrDYpmAE9606	intact-crc:3A2C8ECDA7E3DF35|rigid:QAgHLUiC270GVGiAuKnK088snIY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P26448	uniprotkb:Q8NA61-2	intact:EBI-3824|uniprotkb:D6VZN0|ensemblfungi:YMR055C	intact:EBI-11524851|ensembl:ENSP00000368249|ensembl:ENSP00000480148	psi-mi:bub2_yeast(display_long)|uniprotkb:BUB2(gene name)|psi-mi:BUB2(display_short)|uniprotkb:YMR055C(locus name)|uniprotkb:YM9796.08C(orf name)|uniprotkb:Cell cycle arrest protein BUB2(gene name synonym)	psi-mi:q8na61-2(display_long)|uniprotkb:CBY2(gene name)|psi-mi:CBY2(display_short)|uniprotkb:SPERT(gene name synonym)|uniprotkb:Spermatid-associated protein(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11540224|imex:IM-24995-1880	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013771.1|sgd:S000004659|dip:DIP-1215N|mint:P26448|ensemblfungi:YMR055C(gene)|ensemblfungi:YMR055C_mRNA(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0031030"(negative regulation of septation initiation signaling)|go:"GO:0031578"(mitotic spindle orientation checkpoint signaling)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0051301"(cell division)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:1902543"(negative regulation of protein localization to mitotic spindle pole body)|go:"GO:1990334"(Bfa1-Bub2 complex)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR035969|sgd:YMR055C(identity)	intact:EBI-741724(isoform-parent)|ensembl:ENSG00000174015(gene)|ensembl:ENST00000378966(transcript)|ensembl:ENST00000610924(transcript)|uniprotkb:Q8NA61-2(isoform-parent)|entrezgene/locuslink:220082(identity)	-	crc64:A1DDBFB548E81EA3	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:+03m4HOOcKjpSjqpEZ8wCgD2Egc559292	rogid:SogYcXGGMYRYzB9xKC5o0pEtsDs9606	intact-crc:474EE135D9F9CC51|rigid:aQWoQmRaxtbCXfezUSu0zlJ/56g	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P26448	uniprotkb:Q8N6Y0	intact:EBI-3824|uniprotkb:D6VZN0|ensemblfungi:YMR055C	intact:EBI-739895|uniprotkb:Q8NBX7|uniprotkb:Q96KH3|uniprotkb:Q9BYI8|uniprotkb:A8K7L6|uniprotkb:B2RCR9|ensembl:ENSP00000252597	psi-mi:bub2_yeast(display_long)|uniprotkb:BUB2(gene name)|psi-mi:BUB2(display_short)|uniprotkb:YMR055C(locus name)|uniprotkb:YM9796.08C(orf name)|uniprotkb:Cell cycle arrest protein BUB2(gene name synonym)	psi-mi:usbp1_human(display_long)|uniprotkb:USHBP1(gene name)|psi-mi:USHBP1(display_short)|uniprotkb:MCC-2(gene name synonym)|uniprotkb:AIE-75-binding protein(gene name synonym)|uniprotkb:AIEBP(gene name synonym)|uniprotkb:MCC2(gene name synonym)|uniprotkb:Mutated in colon cancer protein 2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11540215|imex:IM-24995-1879	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013771.1|sgd:S000004659|dip:DIP-1215N|mint:P26448|ensemblfungi:YMR055C(gene)|ensemblfungi:YMR055C_mRNA(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0031030"(negative regulation of septation initiation signaling)|go:"GO:0031578"(mitotic spindle orientation checkpoint signaling)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0051301"(cell division)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:1902543"(negative regulation of protein localization to mitotic spindle pole body)|go:"GO:1990334"(Bfa1-Bub2 complex)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR035969|sgd:YMR055C(identity)	refseq:NP_001284632.1|refseq:NP_114147.2|refseq:NP_001308346.1|ensembl:ENSG00000130307(gene)|ensembl:ENST00000252597(transcript)|go:"GO:0030165"(PDZ domain binding)|interpro:IPR019536|interpro:IPR040171|entrezgene/locuslink:83878(identity)	-	crc64:A1DDBFB548E81EA3	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:+03m4HOOcKjpSjqpEZ8wCgD2Egc559292	rogid:vY1qx73Ju/z7WDu6k1kd10ZDVRo9606	intact-crc:FEE6B37C0B170468|rigid:OJuPXnRBhcxEYj7Fg2EWN3c+DGI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P26448	uniprotkb:Q5JST6	intact:EBI-3824|uniprotkb:D6VZN0|ensemblfungi:YMR055C	intact:EBI-2349927|uniprotkb:Q9H653|uniprotkb:Q5JST8|uniprotkb:Q68DK4|uniprotkb:Q8NEI0|intact:EBI-28971886|ensembl:ENSP00000404232	psi-mi:bub2_yeast(display_long)|uniprotkb:BUB2(gene name)|psi-mi:BUB2(display_short)|uniprotkb:YMR055C(locus name)|uniprotkb:YM9796.08C(orf name)|uniprotkb:Cell cycle arrest protein BUB2(gene name synonym)	psi-mi:efhc2_human(display_long)|uniprotkb:EFHC2(gene name)|psi-mi:EFHC2(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11540206|imex:IM-24995-1878	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013771.1|sgd:S000004659|dip:DIP-1215N|mint:P26448|ensemblfungi:YMR055C(gene)|ensemblfungi:YMR055C_mRNA(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0031030"(negative regulation of septation initiation signaling)|go:"GO:0031578"(mitotic spindle orientation checkpoint signaling)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0051301"(cell division)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:1902543"(negative regulation of protein localization to mitotic spindle pole body)|go:"GO:1990334"(Bfa1-Bub2 complex)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR035969|sgd:YMR055C(identity)	ensembl:ENSP00000404232|refseq:NP_079460.2|ensembl:ENSG00000183690(gene)|ensembl:ENST00000420999(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005930"(axoneme)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0060285"(cilium-dependent cell motility)|go:"GO:0072686"(mitotic spindle)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR006602(Region of unknown function DM10)|interpro:IPR011992(EF-Hand type)|interpro:IPR040193|rcsb pdb:2Z13|rcsb pdb:2Z14|entrezgene/locuslink:80258(identity)	-	crc64:A1DDBFB548E81EA3	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:+03m4HOOcKjpSjqpEZ8wCgD2Egc559292	rogid:O1XriQSkLcYkk7H7AlanQ1FKIBY9606	intact-crc:975BD39155ADB76E|rigid:zdhzFGfHhDSLfJrIv4Q+DERAIGw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P27882	uniprotkb:Q9HD26-2	intact:EBI-6621|uniprotkb:D6VUG4|ensemblfungi:YGR029W	intact:EBI-11102276|ensembl:ENSP00000052569	psi-mi:erv1_yeast(display_long)|uniprotkb:Essential for respiration and vegetative growth protein 1(gene name synonym)|uniprotkb:14 kDa regulatory protein(gene name synonym)|uniprotkb:ERV1(gene name)|psi-mi:ERV1(display_short)|uniprotkb:YGR029W(locus name)	psi-mi:q9hd26-2(display_long)|uniprotkb:GOPC(gene name)|psi-mi:GOPC(display_short)|uniprotkb:CAL(gene name synonym)|uniprotkb:CFTR-associated ligand(gene name synonym)|uniprotkb:FIG(gene name synonym)|uniprotkb:Fused in glioblastoma(gene name synonym)|uniprotkb:PDZ protein interacting specifically with TC10(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11540271|imex:IM-24995-1885	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011543.4|sgd:S000003261|interpro:IPR017905|interpro:IPR036774|mint:P27882|interpro:IPR039799|ensemblfungi:YGR029W(gene)|ensemblfungi:YGR029W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0016971"(flavin-linked sulfhydryl oxidase activity)|go:"GO:0016972"(thiol oxidase activity)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0045041"(protein import into mitochondrial intermembrane space)|go:"GO:0050660"(flavin adenine dinucleotide binding)|rcsb pdb:3W4Y|rcsb pdb:4E0H|rcsb pdb:4E0I|sgd:YGR029W(identity)	ensembl:ENSG00000047932(gene)|ensembl:ENST00000052569(transcript)|intact:EBI-349832(isoform-parent)|uniprotkb:Q9HD26-2(isoform-parent)|entrezgene/locuslink:57120(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:nYYS2xiutIkSeWN8DabWui0hzr4559292	rogid:QoEGY54FfmwTrpGVMQN9ASGPgVI9606	intact-crc:28B11D0ED905493B|rigid:xOqd6gwSBIX/gIXoj2DzzoCzauI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P63279	uniprotkb:P27515	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	intact:EBI-20151|uniprotkb:D6W1I7|ensemblfungi:YNR012W	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:urk1_yeast(display_long)|uniprotkb:URK1(gene name)|psi-mi:URK1(display_short)|uniprotkb:YNR012W(locus name)|uniprotkb:N2050(orf name)|uniprotkb:Uridine monophosphokinase(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11540262|imex:IM-24995-1884	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N|entrezgene/locuslink:7329(identity)	refseq:NP_014409.1|sgd:S000005295|ensemblfungi:YNR012W(gene)|ensemblfungi:YNR012W_mRNA(transcript)|go:"GO:0004849"(uridine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008655"(pyrimidine-containing compound salvage)|go:"GO:0009116"(nucleoside metabolic process)|go:"GO:0044206"(UMP salvage)|go:"GO:0044211"(CTP salvage)|interpro:IPR000764(Uridine kinase)|interpro:IPR000836(Phosphoribosyltransferase)|interpro:IPR006083(Phosphoribulokinase/uridine kinase)|interpro:IPR027417|interpro:IPR029057|dip:DIP-1720N|reactome:R-SCE-196807|reactome:R-SCE-73614|sgd:YNR012W(identity)	-	-	crc64:30A0592899BCD040	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	rogid:0b4r1zm128hRdLTzXIPi6wctZZE559292	intact-crc:EFC71F345E63DB6B|rigid:yK2Y7p5AY+W2Gkq+u9zS/BqQUX4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q14141-4	uniprotkb:P27476	intact:EBI-11524882|ensembl:ENSP00000346169	intact:EBI-12274|ensemblfungi:YGR159C|uniprotkb:D6VUT9	psi-mi:q14141-4(display_long)|uniprotkb:SEPTIN6(gene name)|psi-mi:SEPTIN6(display_short)|uniprotkb:KIAA0128(gene name synonym)|uniprotkb:SEP2(gene name synonym)|uniprotkb:SEPT6(gene name synonym)	psi-mi:nsr1_yeast(display_long)|uniprotkb:NSR1(gene name)|psi-mi:NSR1(display_short)|uniprotkb:YGR159C(locus name)|uniprotkb:G7001(orf name)|uniprotkb:p67(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11540251|imex:IM-24995-1883	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000125354(gene)|ensembl:ENST00000354228(transcript)|intact:EBI-745901(isoform-parent)|entrezgene/locuslink:23157(identity)	ensemblfungi:YGR159C(gene)|ensemblfungi:YGR159C_mRNA(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006364"(rRNA processing)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0043047"(single-stranded telomeric DNA binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034276|interpro:IPR035979|interpro:IPR034272|refseq:NP_011675.1|sgd:S000003391|mint:P27476|dip:DIP-5537N|sgd:YGR159C(identity)	-	-	crc64:90DEEE7BBC20BC0C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:QfLbdoBUG/Q5IYeoadJOtAK+kj49606	rogid:q0/AgJC55iTpn/5kCsxal2kQ7Ls559292	intact-crc:54BB9B5FBE3FA41C|rigid:XNO6KTqFQk4W9Ap+A+2Gcj+WX/A	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P14373	uniprotkb:P28004	intact:EBI-719493|uniprotkb:A2BE15|uniprotkb:Q5RJA8|uniprotkb:Q5ST26|uniprotkb:Q6LA73|uniprotkb:Q6NXR9|uniprotkb:Q9BZY6|uniprotkb:Q9UJL3|ensembl:ENSP00000383555|ensembl:ENSP00000392787|ensembl:ENSP00000405229|ensembl:ENSP00000414793|ensembl:ENSP00000366404	intact:EBI-20640|uniprotkb:D6VPI6|ensemblfungi:YAL032C	psi-mi:tri27_human(display_long)|uniprotkb:TRIM27(gene name)|psi-mi:TRIM27(display_short)|uniprotkb:RNF76(gene name synonym)|uniprotkb:RFP(gene name synonym)|uniprotkb:Ret finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 27(gene name synonym)|uniprotkb:RING finger protein 76(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM27(gene name synonym)	psi-mi:prp45_yeast(display_long)|uniprotkb:YAL032C(locus name)|uniprotkb:PRP45(gene name)|psi-mi:PRP45(display_short)|uniprotkb:FUN20(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11540311|imex:IM-24995-1889	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006501.1|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0090281"(negative regulation of calcium ion import)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR020457|interpro:IPR035791|interpro:IPR043136|mint:P14373|reactome:R-HSA-3232142|reactome:R-HSA-9635465|reactome:R-HSA-8948751|ensembl:ENSG00000204713(gene)|ensembl:ENSG00000215641(gene)|ensembl:ENSG00000229006(gene)|ensembl:ENSG00000234495(gene)|ensembl:ENSG00000237071(gene)|ensembl:ENST00000377199(transcript)|ensembl:ENST00000400720(transcript)|ensembl:ENST00000431123(transcript)|ensembl:ENST00000435528(transcript)|ensembl:ENST00000437160(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001650"(fibrillar center)|go:"GO:0002820"(negative regulation of adaptive immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|entrezgene/locuslink:5987(identity)	refseq:NP_009370.1|sgd:S000000030|ensemblfungi:YAL032C(gene)|ensemblfungi:YAL032C_mRNA(transcript)|go:"GO:0000350"(generation of catalytic spliceosome for second transesterification step)|go:"GO:0005634"(nucleus)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|interpro:IPR004015(SKIP/SNW)|interpro:IPR017862|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|dip:DIP-2774N|mint:P28004|sgd:YAL032C(identity)	-	-	crc64:FE5A724186D7FE84	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:dsfH5OUghD8KSaTz1SFw9OYVTK49606	rogid:qoHF1UsO3k+JOTOfigSuy2P84/k559292	intact-crc:DD567089A0A15255|rigid:l1EOZvLuHrmcXFflP1U/fSP6oOQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P28004	uniprotkb:O95751	intact:EBI-20640|uniprotkb:D6VPI6|ensemblfungi:YAL032C	intact:EBI-740738|ensembl:ENSP00000359557|uniprotkb:Q6IAR6	psi-mi:prp45_yeast(display_long)|uniprotkb:YAL032C(locus name)|uniprotkb:PRP45(gene name)|psi-mi:PRP45(display_short)|uniprotkb:FUN20(gene name synonym)	psi-mi:ldoc1_human(display_long)|uniprotkb:Leucine zipper protein down-regulated in cancer cells(gene name synonym)|uniprotkb:LDOC1(gene name)|psi-mi:LDOC1(display_short)|uniprotkb:BCUR1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11540302|imex:IM-24995-1888	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009370.1|sgd:S000000030|ensemblfungi:YAL032C(gene)|ensemblfungi:YAL032C_mRNA(transcript)|go:"GO:0000350"(generation of catalytic spliceosome for second transesterification step)|go:"GO:0005634"(nucleus)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|interpro:IPR004015(SKIP/SNW)|interpro:IPR017862|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|dip:DIP-2774N|mint:P28004|sgd:YAL032C(identity)	refseq:NP_036449.1|ensembl:ENSG00000182195(gene)|ensembl:ENST00000370526(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071225"(cellular response to muramyl dipeptide)|interpro:IPR032549|interpro:IPR032567|entrezgene/locuslink:23641(identity)	-	crc64:FE5A724186D7FE84	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:qoHF1UsO3k+JOTOfigSuy2P84/k559292	rogid:Ediu0oNiZ/+YVY8l3fNdgP5A+v09606	intact-crc:98ED11758680224C|rigid:5eAIzeJUFQEBthjaT++xS7X6z0Y	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O15156-2	uniprotkb:P28004	intact:EBI-11522250|ensembl:ENSP00000406286	intact:EBI-20640|uniprotkb:D6VPI6|ensemblfungi:YAL032C	psi-mi:o15156-2(display_long)|uniprotkb:ZBTB7B(gene name)|psi-mi:ZBTB7B(display_short)|uniprotkb:Krueppel-related zinc finger protein cKrox(gene name synonym)|uniprotkb:T-helper-inducing POZ/Krueppel-like factor(gene name synonym)|uniprotkb:ZBTB15(gene name synonym)|uniprotkb:ZFP67(gene name synonym)|uniprotkb:ZNF857B(gene name synonym)|uniprotkb:Zinc finger and BTB domain-containing protein 15(gene name synonym)|uniprotkb:Zinc finger protein 67 homolog(gene name synonym)|uniprotkb:Zinc finger protein 857B(gene name synonym)|uniprotkb:Zinc finger protein Th-POK(gene name synonym)	psi-mi:prp45_yeast(display_long)|uniprotkb:YAL032C(locus name)|uniprotkb:PRP45(gene name)|psi-mi:PRP45(display_short)|uniprotkb:FUN20(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11540291|imex:IM-24995-1887	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-740434(isoform-parent)|ensembl:ENSG00000160685(gene)|ensembl:ENST00000417934(transcript)|uniprotkb:O15156-2(isoform-parent)|entrezgene/locuslink:51043(identity)	refseq:NP_009370.1|sgd:S000000030|ensemblfungi:YAL032C(gene)|ensemblfungi:YAL032C_mRNA(transcript)|go:"GO:0000350"(generation of catalytic spliceosome for second transesterification step)|go:"GO:0005634"(nucleus)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|interpro:IPR004015(SKIP/SNW)|interpro:IPR017862|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|dip:DIP-2774N|mint:P28004|sgd:YAL032C(identity)	-	isoform-comment:No experimental confirmation available.	crc64:FE5A724186D7FE84	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:41NEFYyprTXI+fOHVFh78TPKF289606	rogid:qoHF1UsO3k+JOTOfigSuy2P84/k559292	intact-crc:1E7DC896548B9CB9|rigid:8oaC+Ggh9JirICSVORCrzjxdpwY	false	sufficient binding region:35-573	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q08379	uniprotkb:P28004	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	intact:EBI-20640|uniprotkb:D6VPI6|ensemblfungi:YAL032C	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:prp45_yeast(display_long)|uniprotkb:YAL032C(locus name)|uniprotkb:PRP45(gene name)|psi-mi:PRP45(display_short)|uniprotkb:FUN20(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11540280|imex:IM-24995-1886	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N|entrezgene/locuslink:2801(identity)	refseq:NP_009370.1|sgd:S000000030|ensemblfungi:YAL032C(gene)|ensemblfungi:YAL032C_mRNA(transcript)|go:"GO:0000350"(generation of catalytic spliceosome for second transesterification step)|go:"GO:0005634"(nucleus)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|interpro:IPR004015(SKIP/SNW)|interpro:IPR017862|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|dip:DIP-2774N|mint:P28004|sgd:YAL032C(identity)	-	-	crc64:FE5A724186D7FE84	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2017/05/26	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	rogid:qoHF1UsO3k+JOTOfigSuy2P84/k559292	intact-crc:F2918E6380ABD234|rigid:X6brJ2YxTeJSL1sKbSylOWcmUo0	false	sufficient binding region:383-1002	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P28004	uniprotkb:Q13643	intact:EBI-20640|uniprotkb:D6VPI6|ensemblfungi:YAL032C	intact:EBI-741101|ensembl:ENSP00000362107|uniprotkb:Q6I9T0|uniprotkb:Q9BVA2|uniprotkb:D3DPT6	psi-mi:prp45_yeast(display_long)|uniprotkb:YAL032C(locus name)|uniprotkb:PRP45(gene name)|psi-mi:PRP45(display_short)|uniprotkb:FUN20(gene name synonym)	psi-mi:fhl3_human(display_long)|uniprotkb:FHL3(gene name)|psi-mi:FHL3(display_short)|uniprotkb:SLIM2(gene name synonym)|uniprotkb:Skeletal muscle LIM-protein 2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11540356|imex:IM-24995-1894	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009370.1|sgd:S000000030|ensemblfungi:YAL032C(gene)|ensemblfungi:YAL032C_mRNA(transcript)|go:"GO:0000350"(generation of catalytic spliceosome for second transesterification step)|go:"GO:0005634"(nucleus)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|interpro:IPR004015(SKIP/SNW)|interpro:IPR017862|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|dip:DIP-2774N|mint:P28004|sgd:YAL032C(identity)	refseq:NP_004459.2|ensembl:ENSG00000183386(gene)|ensembl:ENST00000373016(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005925"(focal adhesion)|go:"GO:0007517"(muscle organ development)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0046872"(metal ion binding)|interpro:IPR001781(Zinc finger, LIM-type)|mint:Q13643|rcsb pdb:1WYH|rcsb pdb:2CUQ|rcsb pdb:2EHE|interpro:IPR037987|refseq:NP_001230807.1|dip:DIP-42030N|entrezgene/locuslink:2275(identity)	-	crc64:FE5A724186D7FE84	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:qoHF1UsO3k+JOTOfigSuy2P84/k559292	rogid:RAo+b/VgFSnHSbgR+zXuxJvypxM9606	intact-crc:830525F26AD4EF9E|rigid:B/hjQikOusZuoTzjXLPHZWJuQHk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q13422-7	uniprotkb:P28004	intact:EBI-11522367|ensembl:ENSP00000352123|ensembl:ENSP00000413025	intact:EBI-20640|uniprotkb:D6VPI6|ensemblfungi:YAL032C	psi-mi:q13422-7(display_long)|uniprotkb:IKZF1(gene name)|psi-mi:IKZF1(display_short)|uniprotkb:IK1(gene name synonym)|uniprotkb:IKAROS(gene name synonym)|uniprotkb:Ikaros family zinc finger protein 1(gene name synonym)|uniprotkb:LYF1(gene name synonym)|uniprotkb:Lymphoid transcription factor LyF-1(gene name synonym)|uniprotkb:ZNFN1A1(gene name synonym)	psi-mi:prp45_yeast(display_long)|uniprotkb:YAL032C(locus name)|uniprotkb:PRP45(gene name)|psi-mi:PRP45(display_short)|uniprotkb:FUN20(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11540347|imex:IM-24995-1893	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-745305(isoform-parent)|ensembl:ENSG00000185811(gene)|ensembl:ENST00000359197(transcript)|ensembl:ENST00000439701(transcript)|uniprotkb:Q13422-7(isoform-parent)|entrezgene/locuslink:10320(identity)	refseq:NP_009370.1|sgd:S000000030|ensemblfungi:YAL032C(gene)|ensemblfungi:YAL032C_mRNA(transcript)|go:"GO:0000350"(generation of catalytic spliceosome for second transesterification step)|go:"GO:0005634"(nucleus)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|interpro:IPR004015(SKIP/SNW)|interpro:IPR017862|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|dip:DIP-2774N|mint:P28004|sgd:YAL032C(identity)	-	-	crc64:FE5A724186D7FE84	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:ou/ovXYoMneBNVp4pj38VxenfyY9606	rogid:qoHF1UsO3k+JOTOfigSuy2P84/k559292	intact-crc:67697A6630B4CB09|rigid:WMydF67ZCWFq4i6PYP0NLZP8YGw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P43365	uniprotkb:P28004	intact:EBI-749530|uniprotkb:Q9NSD3|intact:EBI-10178394|uniprotkb:Q6FHH8|ensembl:ENSP00000350592|ensembl:ENSP00000377447|ensembl:ENSP00000377478	intact:EBI-20640|uniprotkb:D6VPI6|ensemblfungi:YAL032C	psi-mi:magac_human(display_long)|uniprotkb:MAGE-12 antigen(gene name synonym)|uniprotkb:MAGE12F antigen(gene name synonym)|uniprotkb:Cancer/testis antigen 1.12(gene name synonym)|uniprotkb:MAGEA12(gene name)|psi-mi:MAGEA12(display_short)|uniprotkb:MAGE12(gene name synonym)	psi-mi:prp45_yeast(display_long)|uniprotkb:YAL032C(locus name)|uniprotkb:PRP45(gene name)|psi-mi:PRP45(display_short)|uniprotkb:FUN20(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11540338|imex:IM-24995-1892	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001159858.1|refseq:NP_001159859.1|refseq:NP_005358.2|ensembl:ENSG00000213401(gene)|ensembl:ENST00000357916(transcript)|ensembl:ENST00000393869(transcript)|ensembl:ENST00000393900(transcript)|interpro:IPR002190(MAGE protein)|interpro:IPR021072|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|entrezgene/locuslink:4111(identity)	refseq:NP_009370.1|sgd:S000000030|ensemblfungi:YAL032C(gene)|ensemblfungi:YAL032C_mRNA(transcript)|go:"GO:0000350"(generation of catalytic spliceosome for second transesterification step)|go:"GO:0005634"(nucleus)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|interpro:IPR004015(SKIP/SNW)|interpro:IPR017862|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|dip:DIP-2774N|mint:P28004|sgd:YAL032C(identity)	-	-	crc64:FE5A724186D7FE84	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:3/Jxz2VsFOb67RWqWj3xbTrw3s49606	rogid:qoHF1UsO3k+JOTOfigSuy2P84/k559292	intact-crc:7466794270363810|rigid:G+FbStO3V9B8noWIKuGba0HFTkE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P43355	uniprotkb:P28004	intact:EBI-740978|ensembl:ENSP00000349085|uniprotkb:O00346|uniprotkb:B2RC81	intact:EBI-20640|uniprotkb:D6VPI6|ensemblfungi:YAL032C	psi-mi:maga1_human(display_long)|uniprotkb:MAGE-1 antigen(gene name synonym)|uniprotkb:Antigen MZ2-E(gene name synonym)|uniprotkb:Cancer/testis antigen 1.1(gene name synonym)|uniprotkb:MAGEA1(gene name)|psi-mi:MAGEA1(display_short)|uniprotkb:MAGE1(gene name synonym)|uniprotkb:MAGE1A(gene name synonym)	psi-mi:prp45_yeast(display_long)|uniprotkb:YAL032C(locus name)|uniprotkb:PRP45(gene name)|psi-mi:PRP45(display_short)|uniprotkb:FUN20(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11540329|imex:IM-24995-1891	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004979.3|ensembl:ENSG00000198681(gene)|ensembl:ENST00000356661(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|interpro:IPR002190(MAGE protein)|interpro:IPR021072|interpro:IPR030093|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|rcsb pdb:1W72|rcsb pdb:3BO8|dip:DIP-54794N|entrezgene/locuslink:4100(identity)	refseq:NP_009370.1|sgd:S000000030|ensemblfungi:YAL032C(gene)|ensemblfungi:YAL032C_mRNA(transcript)|go:"GO:0000350"(generation of catalytic spliceosome for second transesterification step)|go:"GO:0005634"(nucleus)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|interpro:IPR004015(SKIP/SNW)|interpro:IPR017862|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|dip:DIP-2774N|mint:P28004|sgd:YAL032C(identity)	-	crc64:544EEB1F9F4E9D33	crc64:FE5A724186D7FE84	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:6XW3mnTNM3yvOtXmiFbU8Uz3hjA9606	rogid:qoHF1UsO3k+JOTOfigSuy2P84/k559292	intact-crc:51210FE3032C5D36|rigid:atlGVCsRYtMXruwX/AYXgfjHlJs	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P19012	uniprotkb:P28004	intact:EBI-739566|uniprotkb:Q53XV8|uniprotkb:Q9BUG4|uniprotkb:B3KQY1|uniprotkb:B3KRA2|uniprotkb:E0CX14|ensembl:ENSP00000254043|ensembl:ENSP00000377546	intact:EBI-20640|uniprotkb:D6VPI6|ensemblfungi:YAL032C	psi-mi:k1c15_human(display_long)|uniprotkb:KRT15(gene name)|psi-mi:KRT15(display_short)|uniprotkb:KRTB(gene name synonym)|uniprotkb:Cytokeratin-15(gene name synonym)|uniprotkb:Keratin-15(gene name synonym)	psi-mi:prp45_yeast(display_long)|uniprotkb:YAL032C(locus name)|uniprotkb:PRP45(gene name)|psi-mi:PRP45(display_short)|uniprotkb:FUN20(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11540320|imex:IM-24995-1890	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002266.2|ensembl:ENSG00000171346(gene)|ensembl:ENST00000254043(transcript)|ensembl:ENST00000393976(transcript)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0008544"(epidermis development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097110"(scaffold protein binding)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR039008|mint:P19012|reactome:R-HSA-6805567|reactome:R-HSA-6809371|entrezgene/locuslink:3866(identity)	refseq:NP_009370.1|sgd:S000000030|ensemblfungi:YAL032C(gene)|ensemblfungi:YAL032C_mRNA(transcript)|go:"GO:0000350"(generation of catalytic spliceosome for second transesterification step)|go:"GO:0005634"(nucleus)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|interpro:IPR004015(SKIP/SNW)|interpro:IPR017862|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|dip:DIP-2774N|mint:P28004|sgd:YAL032C(identity)	-	-	crc64:FE5A724186D7FE84	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:WrZQBYQvrWcfrR5ojWXrXp6spPE9606	rogid:qoHF1UsO3k+JOTOfigSuy2P84/k559292	intact-crc:D5641346D210069F|rigid:4w+BxVSaSSy0ukWUMAf8EPr4mzM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P28004	uniprotkb:Q8IYF3-3	intact:EBI-20640|uniprotkb:D6VPI6|ensemblfungi:YAL032C	intact:EBI-11523345|ensembl:ENSP00000363453	psi-mi:prp45_yeast(display_long)|uniprotkb:YAL032C(locus name)|uniprotkb:PRP45(gene name)|psi-mi:PRP45(display_short)|uniprotkb:FUN20(gene name synonym)	psi-mi:q8iyf3-3(display_long)|uniprotkb:TEX11(gene name)|psi-mi:TEX11(display_short)|uniprotkb:Protein ZIP4 homolog(gene name synonym)|uniprotkb:ZIP4(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11540383|imex:IM-24995-1897	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009370.1|sgd:S000000030|ensemblfungi:YAL032C(gene)|ensemblfungi:YAL032C_mRNA(transcript)|go:"GO:0000350"(generation of catalytic spliceosome for second transesterification step)|go:"GO:0005634"(nucleus)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|interpro:IPR004015(SKIP/SNW)|interpro:IPR017862|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|dip:DIP-2774N|mint:P28004|sgd:YAL032C(identity)	ensembl:ENSG00000120498(gene)|ensembl:ENST00000374333(transcript)|intact:EBI-742397(isoform-parent)|uniprotkb:Q8IYF3-3(isoform-parent)|entrezgene/locuslink:56159(identity)	-	crc64:FE5A724186D7FE84	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:qoHF1UsO3k+JOTOfigSuy2P84/k559292	rogid:PUAMFmnm5ZV2rnJ1rhm9ZeRCixg9606	intact-crc:482EA7C59F9ADF48|rigid:bFlrER27s5qGZWGKEo74cSVGA2Y	false	-	sufficient binding region:9-925	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q5T124-6	uniprotkb:P28004	intact:EBI-11524408	intact:EBI-20640|uniprotkb:D6VPI6|ensemblfungi:YAL032C	psi-mi:q5t124-6(display_long)|uniprotkb:UBXN11(gene name)|psi-mi:UBXN11(display_short)|uniprotkb:Colorectal tumor-associated antigen COA-1(gene name synonym)|uniprotkb:SOC(gene name synonym)|uniprotkb:Socius(gene name synonym)|uniprotkb:UBX domain-containing protein 5(gene name synonym)|uniprotkb:UBXD5(gene name synonym)|uniprotkb:PP2243(orf name)	psi-mi:prp45_yeast(display_long)|uniprotkb:YAL032C(locus name)|uniprotkb:PRP45(gene name)|psi-mi:PRP45(display_short)|uniprotkb:FUN20(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11540374|imex:IM-24995-1896	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-746004(isoform-parent)|uniprotkb:Q5T124-6(isoform-parent)|entrezgene/locuslink:91544(identity)	refseq:NP_009370.1|sgd:S000000030|ensemblfungi:YAL032C(gene)|ensemblfungi:YAL032C_mRNA(transcript)|go:"GO:0000350"(generation of catalytic spliceosome for second transesterification step)|go:"GO:0005634"(nucleus)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|interpro:IPR004015(SKIP/SNW)|interpro:IPR017862|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|dip:DIP-2774N|mint:P28004|sgd:YAL032C(identity)	-	-	crc64:FE5A724186D7FE84	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:1YSjG/p2ihcjl4P8KdPCaX2HxiY9606	rogid:qoHF1UsO3k+JOTOfigSuy2P84/k559292	intact-crc:7CA343E4148D8BA0|rigid:LrNsNOcmHu7Nauf8ed4RBHZX+Wg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q5JR59-3	uniprotkb:P28004	intact:EBI-11522433|ensembl:ENSP00000370186	intact:EBI-20640|uniprotkb:D6VPI6|ensemblfungi:YAL032C	psi-mi:q5jr59-3(display_long)|uniprotkb:MTUS2(gene name)|psi-mi:MTUS2(display_short)|uniprotkb:CAZIP(gene name synonym)|uniprotkb:Cardiac zipper protein(gene name synonym)|uniprotkb:KIAA0774(gene name synonym)|uniprotkb:Microtubule plus-end tracking protein TIP150(gene name synonym)|uniprotkb:TIP150(gene name synonym)	psi-mi:prp45_yeast(display_long)|uniprotkb:YAL032C(locus name)|uniprotkb:PRP45(gene name)|psi-mi:PRP45(display_short)|uniprotkb:FUN20(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11540365|imex:IM-24995-1895	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000132938(gene)|ensembl:ENST00000380808(transcript)|intact:EBI-742948(isoform-parent)|uniprotkb:Q5JR59-3(isoform-parent)|entrezgene/locuslink:23281(identity)	refseq:NP_009370.1|sgd:S000000030|ensemblfungi:YAL032C(gene)|ensemblfungi:YAL032C_mRNA(transcript)|go:"GO:0000350"(generation of catalytic spliceosome for second transesterification step)|go:"GO:0005634"(nucleus)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|interpro:IPR004015(SKIP/SNW)|interpro:IPR017862|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|dip:DIP-2774N|mint:P28004|sgd:YAL032C(identity)	-	isoform-comment:No experimental confirmation available.	crc64:FE5A724186D7FE84	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:npId9tC7VoLN/jteoBiRbSYChPs9606	rogid:qoHF1UsO3k+JOTOfigSuy2P84/k559292	intact-crc:A019CAB94A23F2A6|rigid:+4ZFzEaiSQIi/mKLMudoTNTyewE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P28004	uniprotkb:Q8WWB3	intact:EBI-20640|uniprotkb:D6VPI6|ensemblfungi:YAL032C	intact:EBI-740680|ensembl:ENSP00000361276|ensembl:ENSP00000361278|ensembl:ENSP00000402890|uniprotkb:Q5QP03|uniprotkb:Q5QP04|uniprotkb:Q6WNP4|uniprotkb:Q6ZU87|uniprotkb:A8K927	psi-mi:prp45_yeast(display_long)|uniprotkb:YAL032C(locus name)|uniprotkb:PRP45(gene name)|psi-mi:PRP45(display_short)|uniprotkb:FUN20(gene name synonym)	psi-mi:dydc1_human(display_long)|uniprotkb:DYDC1(gene name)|psi-mi:DYDC1(display_short)|uniprotkb:DPY30D1(gene name synonym)|uniprotkb:RSD9(orf name)|uniprotkb:RSD-9(orf name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11540421|imex:IM-24995-1901	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009370.1|sgd:S000000030|ensemblfungi:YAL032C(gene)|ensemblfungi:YAL032C_mRNA(transcript)|go:"GO:0000350"(generation of catalytic spliceosome for second transesterification step)|go:"GO:0005634"(nucleus)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|interpro:IPR004015(SKIP/SNW)|interpro:IPR017862|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|dip:DIP-2774N|mint:P28004|sgd:YAL032C(identity)	refseq:NP_620167.1|ensembl:ENSG00000170788(gene)|ensembl:ENST00000372202(transcript)|ensembl:ENST00000372204(transcript)|ensembl:ENST00000421924(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0006348"|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|interpro:IPR007858(Dpy-30)|interpro:IPR037856|refseq:XP_011537636.1|refseq:XP_011537637.1|refseq:NP_001255982.1|refseq:XP_005269606.1|refseq:XP_005269607.1|entrezgene/locuslink:143241(identity)	-	crc64:FE5A724186D7FE84	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:qoHF1UsO3k+JOTOfigSuy2P84/k559292	rogid:W6GUazYFXZGHGijUBpAJ5GiRuXA9606	intact-crc:E1340323FBCD9ABC|rigid:m+GJ+aeiVaLiiud/0VLVpK7jNIs	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P28004	uniprotkb:Q8TAP6	intact:EBI-20640|uniprotkb:D6VPI6|ensemblfungi:YAL032C	intact:EBI-742887|ensembl:ENSP00000262127|uniprotkb:Q658N5|uniprotkb:Q9H9U7|uniprotkb:B0YJB2|uniprotkb:B4DXG5|uniprotkb:B4DZW1	psi-mi:prp45_yeast(display_long)|uniprotkb:YAL032C(locus name)|uniprotkb:PRP45(gene name)|psi-mi:PRP45(display_short)|uniprotkb:FUN20(gene name synonym)	psi-mi:cep76_human(display_long)|uniprotkb:CEP76(gene name)|psi-mi:CEP76(display_short)|uniprotkb:C18orf9(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11540412|imex:IM-24995-1900	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009370.1|sgd:S000000030|ensemblfungi:YAL032C(gene)|ensemblfungi:YAL032C_mRNA(transcript)|go:"GO:0000350"(generation of catalytic spliceosome for second transesterification step)|go:"GO:0005634"(nucleus)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|interpro:IPR004015(SKIP/SNW)|interpro:IPR017862|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|dip:DIP-2774N|mint:P28004|sgd:YAL032C(identity)	refseq:NP_079175.2|ensembl:ENSG00000101624(gene)|ensembl:ENST00000262127(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0046599"(regulation of centriole replication)|interpro:IPR028926|interpro:IPR038765|mint:Q8TAP6|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_001258918.1|entrezgene/locuslink:79959(identity)	-	crc64:FE5A724186D7FE84	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:qoHF1UsO3k+JOTOfigSuy2P84/k559292	rogid:fWzb8oIU35oVWomyDrf8u5sbxUk9606	intact-crc:81E4C5BD617D23DD|rigid:asauxzIqMwX/jnbHM8oNmdgnmJs	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P28004	uniprotkb:Q8NHQ1	intact:EBI-20640|uniprotkb:D6VPI6|ensemblfungi:YAL032C	intact:EBI-739624|ensembl:ENSP00000264982|ensembl:ENSP00000419231|uniprotkb:Q96B31|uniprotkb:Q9H2C3|uniprotkb:Q9H2Z1|uniprotkb:Q9H940|uniprotkb:D3DNE9|uniprotkb:B7Z5I8|uniprotkb:B7Z7E8|uniprotkb:F5GZX8	psi-mi:prp45_yeast(display_long)|uniprotkb:YAL032C(locus name)|uniprotkb:PRP45(gene name)|psi-mi:PRP45(display_short)|uniprotkb:FUN20(gene name synonym)	psi-mi:cep70_human(display_long)|uniprotkb:CEP70(gene name)|psi-mi:CEP70(display_short)|uniprotkb:BITE(gene name synonym)|uniprotkb:p10-binding protein(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11540403|imex:IM-24995-1899	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009370.1|sgd:S000000030|ensemblfungi:YAL032C(gene)|ensemblfungi:YAL032C_mRNA(transcript)|go:"GO:0000350"(generation of catalytic spliceosome for second transesterification step)|go:"GO:0005634"(nucleus)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|interpro:IPR004015(SKIP/SNW)|interpro:IPR017862|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|dip:DIP-2774N|mint:P28004|sgd:YAL032C(identity)	ensembl:ENSG00000114107(gene)|ensembl:ENST00000264982(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|interpro:IPR019734|interpro:IPR037692|mint:Q8NHQ1|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|ensembl:ENST00000484888(transcript)|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_077817.2|refseq:XP_016862764.1|refseq:NP_001275893.1|refseq:NP_001275894.1|refseq:NP_001275895.1|refseq:NP_001275896.1|refseq:NP_001307527.1|refseq:NP_001307529.1|entrezgene/locuslink:80321(identity)	-	crc64:FE5A724186D7FE84	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:qoHF1UsO3k+JOTOfigSuy2P84/k559292	rogid:S4yveQWcvdVtAUX65gqrJ5Dv0Mc9606	intact-crc:F71F70A020947484|rigid:SN4sk0rmyaezL9EELRiB8gngOQ0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8N6Y0	uniprotkb:P28004	intact:EBI-739895|uniprotkb:Q8NBX7|uniprotkb:Q96KH3|uniprotkb:Q9BYI8|uniprotkb:A8K7L6|uniprotkb:B2RCR9|ensembl:ENSP00000252597	intact:EBI-20640|uniprotkb:D6VPI6|ensemblfungi:YAL032C	psi-mi:usbp1_human(display_long)|uniprotkb:USHBP1(gene name)|psi-mi:USHBP1(display_short)|uniprotkb:MCC-2(gene name synonym)|uniprotkb:AIE-75-binding protein(gene name synonym)|uniprotkb:AIEBP(gene name synonym)|uniprotkb:MCC2(gene name synonym)|uniprotkb:Mutated in colon cancer protein 2(gene name synonym)	psi-mi:prp45_yeast(display_long)|uniprotkb:YAL032C(locus name)|uniprotkb:PRP45(gene name)|psi-mi:PRP45(display_short)|uniprotkb:FUN20(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11540394|imex:IM-24995-1898	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001284632.1|refseq:NP_114147.2|refseq:NP_001308346.1|ensembl:ENSG00000130307(gene)|ensembl:ENST00000252597(transcript)|go:"GO:0030165"(PDZ domain binding)|interpro:IPR019536|interpro:IPR040171|entrezgene/locuslink:83878(identity)	refseq:NP_009370.1|sgd:S000000030|ensemblfungi:YAL032C(gene)|ensemblfungi:YAL032C_mRNA(transcript)|go:"GO:0000350"(generation of catalytic spliceosome for second transesterification step)|go:"GO:0005634"(nucleus)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|interpro:IPR004015(SKIP/SNW)|interpro:IPR017862|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|dip:DIP-2774N|mint:P28004|sgd:YAL032C(identity)	-	-	crc64:FE5A724186D7FE84	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:vY1qx73Ju/z7WDu6k1kd10ZDVRo9606	rogid:qoHF1UsO3k+JOTOfigSuy2P84/k559292	intact-crc:BFB4E401D3237ECE|rigid:58s9BfEOehK3LAa3Idmi3Xjo3vE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UDV6	uniprotkb:P28004	intact:EBI-1640204|uniprotkb:Q13396|uniprotkb:Q8N664|uniprotkb:B2RCF4|ensembl:ENSP00000338572	intact:EBI-20640|uniprotkb:D6VPI6|ensemblfungi:YAL032C	psi-mi:zn212_human(display_long)|uniprotkb:ZNF212(gene name)|psi-mi:ZNF212(display_short)|uniprotkb:ZNFC150(gene name synonym)|uniprotkb:Zinc finger protein C2H2-150(gene name synonym)	psi-mi:prp45_yeast(display_long)|uniprotkb:YAL032C(locus name)|uniprotkb:PRP45(gene name)|psi-mi:PRP45(display_short)|uniprotkb:FUN20(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11540457|imex:IM-24995-1905	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_036388.2|ensembl:ENSG00000170260(gene)|ensembl:ENST00000335870(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR022137|interpro:IPR036051|interpro:IPR036236|mint:Q9UDV6|reactome:R-HSA-212436|entrezgene/locuslink:7988(identity)	refseq:NP_009370.1|sgd:S000000030|ensemblfungi:YAL032C(gene)|ensemblfungi:YAL032C_mRNA(transcript)|go:"GO:0000350"(generation of catalytic spliceosome for second transesterification step)|go:"GO:0005634"(nucleus)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|interpro:IPR004015(SKIP/SNW)|interpro:IPR017862|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|dip:DIP-2774N|mint:P28004|sgd:YAL032C(identity)	-	-	crc64:FE5A724186D7FE84	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:jZtScr5t/MR83+d1tdA9OiP4JCA9606	rogid:qoHF1UsO3k+JOTOfigSuy2P84/k559292	intact-crc:B4A2BC81D1F52119|rigid:JZrk/DQKgLpkDiy4/hqJoGL3uvo	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9NSC5	uniprotkb:P28004	intact:EBI-748420|uniprotkb:O14580|uniprotkb:O95350|uniprotkb:Q9NSB9|uniprotkb:Q9NSC0|intact:EBI-2557809|uniprotkb:E9PCW9|uniprotkb:Q9NSC1|intact:EBI-28972925|ensembl:ENSP00000376162|ensembl:ENSP00000439937|ensembl:ENSP00000446026|intact:EBI-10175777|uniprotkb:B2RA10	intact:EBI-20640|uniprotkb:D6VPI6|ensemblfungi:YAL032C	psi-mi:home3_human(display_long)|uniprotkb:HOMER3(gene name)|psi-mi:HOMER3(display_short)	psi-mi:prp45_yeast(display_long)|uniprotkb:YAL032C(locus name)|uniprotkb:PRP45(gene name)|psi-mi:PRP45(display_short)|uniprotkb:FUN20(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11540448|imex:IM-24995-1904	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000221222|ensembl:ENSP00000221222|ensembl:ENSP00000376162|ensembl:ENST00000433218|ensembl:ENSP00000396154|ensembl:ENSP00000439937|ensembl:ENSP00000446026|ensembl:ENST00000594439|ensembl:ENSP00000471835|refseq:XP_006723006.1|refseq:XP_006723007.1|refseq:NP_001139193.1|refseq:NP_001139194.1|refseq:NP_004829.3|refseq:NP_001139196.1|ensembl:ENSG00000051128(gene)|ensembl:ENST00000392351(transcript)|ensembl:ENST00000539827(transcript)|ensembl:ENST00000542541(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006605"(protein targeting)|go:"GO:0007216"(G protein-coupled glutamate receptor signaling pathway)|go:"GO:0014069"(postsynaptic density)|go:"GO:0030425"(dendrite)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0035256"(G protein-coupled glutamate receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|go:"GO:2001256"(regulation of store-operated calcium entry)|interpro:IPR000697(EVH1)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR044100|mint:Q9NSC5|rcsb pdb:2P8V|rcsb pdb:3CVF|reactome:R-HSA-6794361|entrezgene/locuslink:9454(identity)	refseq:NP_009370.1|sgd:S000000030|ensemblfungi:YAL032C(gene)|ensemblfungi:YAL032C_mRNA(transcript)|go:"GO:0000350"(generation of catalytic spliceosome for second transesterification step)|go:"GO:0005634"(nucleus)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|interpro:IPR004015(SKIP/SNW)|interpro:IPR017862|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|dip:DIP-2774N|mint:P28004|sgd:YAL032C(identity)	-	-	crc64:FE5A724186D7FE84	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:U1y/y52nnf7zQUCNQlqk7JDgXi49606	rogid:qoHF1UsO3k+JOTOfigSuy2P84/k559292	intact-crc:8F0028120B4EFC88|rigid:Eduwq3iPRqhvty7rIjhzv5EAGG8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P28004	uniprotkb:Q96MT8-3	intact:EBI-20640|uniprotkb:D6VPI6|ensemblfungi:YAL032C	intact:EBI-11522539|ensembl:ENSP00000507703|ensembl:ENSP00000328382|ensembl:ENSP00000506728|ensembl:ENSP00000506791|ensembl:ENSP00000506828|ensembl:ENSP00000507228	psi-mi:prp45_yeast(display_long)|uniprotkb:YAL032C(locus name)|uniprotkb:PRP45(gene name)|psi-mi:PRP45(display_short)|uniprotkb:FUN20(gene name synonym)	psi-mi:q96mt8-3(display_long)|uniprotkb:CEP63(gene name)|psi-mi:CEP63(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11540439|imex:IM-24995-1903	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009370.1|sgd:S000000030|ensemblfungi:YAL032C(gene)|ensemblfungi:YAL032C_mRNA(transcript)|go:"GO:0000350"(generation of catalytic spliceosome for second transesterification step)|go:"GO:0005634"(nucleus)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|interpro:IPR004015(SKIP/SNW)|interpro:IPR017862|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|dip:DIP-2774N|mint:P28004|sgd:YAL032C(identity)	intact:EBI-741977(isoform-parent)|ensembl:ENST00000332047(transcript)|ensembl:ENST00000682042(transcript)|ensembl:ENST00000682800(transcript)|ensembl:ENST00000682858(transcript)|ensembl:ENST00000683177(transcript)|ensembl:ENST00000683861(transcript)|ensembl:ENSG00000182923(gene)|uniprotkb:Q96MT8-3(isoform-parent)|entrezgene/locuslink:80254(identity)	-	crc64:FE5A724186D7FE84	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:qoHF1UsO3k+JOTOfigSuy2P84/k559292	rogid:U0uvVcOCzA8Qp2cCB0ilixgd4Yc9606	intact-crc:0483604503FBD7BF|rigid:EJ/r7IxMZYX8LJ5I6R1QwOOTrEs	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P28004	uniprotkb:Q8WXE1-3	intact:EBI-20640|uniprotkb:D6VPI6|ensemblfungi:YAL032C	intact:EBI-11524582|ensembl:ENSP00000400930	psi-mi:prp45_yeast(display_long)|uniprotkb:YAL032C(locus name)|uniprotkb:PRP45(gene name)|psi-mi:PRP45(display_short)|uniprotkb:FUN20(gene name synonym)	psi-mi:q8wxe1-3(display_long)|uniprotkb:ATRIP(gene name)|psi-mi:ATRIP(display_short)|uniprotkb:AGS1(gene name synonym)|uniprotkb:ATM and Rad3-related-interacting protein(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11540430|imex:IM-24995-1902	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009370.1|sgd:S000000030|ensemblfungi:YAL032C(gene)|ensemblfungi:YAL032C_mRNA(transcript)|go:"GO:0000350"(generation of catalytic spliceosome for second transesterification step)|go:"GO:0005634"(nucleus)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|interpro:IPR004015(SKIP/SNW)|interpro:IPR017862|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|dip:DIP-2774N|mint:P28004|sgd:YAL032C(identity)	intact:EBI-747353(isoform-parent)|ensembl:ENSG00000164053(gene)|ensembl:ENST00000412052(transcript)|entrezgene/locuslink:84126(identity)	-	crc64:FE5A724186D7FE84	isoform-comment:No experimental confirmation available.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:qoHF1UsO3k+JOTOfigSuy2P84/k559292	rogid:NKCjy1jGZEySEhUOf8rJ6h9pyxY9606	intact-crc:53A7B1B70268B72F|rigid:J70e7vmfBgj+wUTeeimePrYnIzM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P28496	uniprotkb:Q8N6L0	intact:EBI-26585|uniprotkb:D6VXS8|ensemblfungi:YKL008C	intact:EBI-749265|uniprotkb:Q96MC3|ensembl:ENSP00000404220	psi-mi:lac1_yeast(display_long)|uniprotkb:LAC1(gene name)|psi-mi:LAC1(display_short)|uniprotkb:DGT1(gene name synonym)|uniprotkb:Very-long-chain ceramide synthase LAC1(gene name synonym)|uniprotkb:YKL156(orf name)|uniprotkb:YKL008C(locus name)	psi-mi:kash5_human(display_long)|uniprotkb:KASH5(gene name)|psi-mi:KASH5(display_short)|uniprotkb:CCDC155(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 155(gene name synonym)|uniprotkb:KASH domain-containing protein 5(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11540502|imex:IM-24995-1910	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000001491|refseq:NP_012917.3|mint:P28496|dip:DIP-4348N|ensemblfungi:YKL008C(gene)|ensemblfungi:YKL008C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016410"(N-acyltransferase activity)|go:"GO:0034399"(nuclear periphery)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:0050291"(sphingosine N-acyltransferase activity)|go:"GO:0061576"(acyl-CoA ceramide synthase complex)|interpro:IPR006634(TRAM, LAG1 and CLN8 homology)|interpro:IPR013599(TRAM1-like protein)|interpro:IPR016439(Longevity assurance, LAG1/LAC1)|reactome:R-SCE-1660661|sgd:YKL008C(identity)	refseq:NP_653289.3|ensembl:ENSG00000161609(gene)|ensembl:ENST00000447857(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034397"(telomere localization)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051225"(spindle assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0090172"(microtubule cytoskeleton organization involved in homologous chromosome segregation)|go:"GO:0090220"(chromosome localization to nuclear envelope involved in homologous chromosome segregation)|go:"GO:0090619"(meiotic spindle pole)|interpro:IPR011992(EF-Hand type)|interpro:IPR028168|interpro:IPR028170|interpro:IPR039508|mint:Q8N6L0|rcsb pdb:6R2I|rcsb pdb:6WMF|entrezgene/locuslink:147872(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:gqRCCAHQcrRAHNO+R2LkQOzJ0mg559292	rogid:Wl9L7AcvDHCZuKjYLn8QgGIbZTc9606	intact-crc:EBB7B438CA1EC9FB|rigid:uxF2JNsk6pUSjMh4HBozlamYkDE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P14136	uniprotkb:P28272	intact:EBI-744302|uniprotkb:Q53H98|uniprotkb:Q5D055|uniprotkb:Q6ZQS3|uniprotkb:Q7Z5J6|uniprotkb:Q7Z5J7|uniprotkb:Q96KS4|uniprotkb:Q96P18|uniprotkb:Q9UFD0|uniprotkb:B2RD44|uniprotkb:D3DX59|intact:EBI-3909365|uniprotkb:E9PAX3|ensembl:ENSP00000466598|uniprotkb:A7REI1	intact:EBI-14386|uniprotkb:Q2XN75|uniprotkb:Q70DC7|uniprotkb:D6VWY7|ensemblfungi:YKL216W	psi-mi:gfap_human(display_long)|uniprotkb:GFAP(gene name)|psi-mi:GFAP(display_short)	psi-mi:pyrd_yeast(display_long)|uniprotkb:YKL216W(locus name)|uniprotkb:URA1(gene name)|psi-mi:URA1(display_short)|uniprotkb:Dihydroorotate oxidase(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11540493|imex:IM-24995-1909	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001124491.1|refseq:NP_001229305.1|refseq:NP_002046.1|ensembl:ENSG00000131095(gene)|ensembl:ENST00000588735(transcript)|go:"GO:0005178"(integrin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0009611"(response to wounding)|go:"GO:0010467"(gene expression)|go:"GO:0010625"(positive regulation of Schwann cell proliferation)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0014002"(astrocyte development)|go:"GO:0019900"(kinase binding)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0031102"(neuron projection regeneration)|go:"GO:0042802"(identical protein binding)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0044297"(cell body)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0051580"(regulation of neurotransmitter uptake)|go:"GO:0060020"(Bergmann glial cell differentiation)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0070779"(D-aspartate import across plasma membrane)|go:"GO:0097450"(astrocyte end-foot)|go:"GO:0098574"(cytoplasmic side of lysosomal membrane)|go:"GO:1904714"(regulation of chaperone-mediated autophagy)|interpro:IPR006821(Intermediate filament, DNA-binding region)|interpro:IPR018039|interpro:IPR027701|interpro:IPR039008|mint:P14136|rcsb pdb:6A9P|reactome:R-HSA-1251985|reactome:R-HSA-9613829|entrezgene/locuslink:2670(identity)	interpro:IPR023359|interpro:IPR024920|interpro:IPR033886|ensemblfungi:YKL216W(gene)|ensemblfungi:YKL216W_mRNA(transcript)|go:"GO:0004152"(dihydroorotate dehydrogenase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006207"('de novo' pyrimidine nucleobase biosynthetic process)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0044205"('de novo' UMP biosynthetic process)|go:"GO:1990663"("dihydroorotate dehydrogenase (fumarate) activity")|interpro:IPR001295(Dihydroorotate dehydrogenase, core)|interpro:IPR005720(Dihydroorotate dehydrogenase, class 1, core)|interpro:IPR012135(Dihydroorotate dehydrogenase, classes 1 and 2)|interpro:IPR013785(Aldolase-type TIM barrel)|refseq:NP_012706.1|sgd:S000001699|mint:P28272|dip:DIP-6573N|sgd:YKL216W(identity)	-	-	crc64:0F1FF9BDA7F8D68E	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Pz4JW0WjMjBYILTDSX9jUmMqWhg9606	rogid:EXmeAujwfMfvIaNkgvsl3YgWvPs559292	intact-crc:D746FD334893D780|rigid:AAroZq4KgO2UidBnxyZ6aHWVpTA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P28004	uniprotkb:Q9Y6D9	intact:EBI-20640|uniprotkb:D6VPI6|ensemblfungi:YAL032C	intact:EBI-742610|uniprotkb:B3KR41|uniprotkb:Q9UNH0|uniprotkb:Q13312|uniprotkb:Q75MI0|uniprotkb:Q86UM4|ensembl:ENSP00000265854|ensembl:ENSP00000382562|ensembl:ENSP00000385334	psi-mi:prp45_yeast(display_long)|uniprotkb:YAL032C(locus name)|uniprotkb:PRP45(gene name)|psi-mi:PRP45(display_short)|uniprotkb:FUN20(gene name synonym)	psi-mi:md1l1_human(display_long)|uniprotkb:Mitotic arrest deficient 1-like protein 1(gene name synonym)|uniprotkb:Mitotic checkpoint MAD1 protein homolog(gene name synonym)|uniprotkb:Tax-binding protein 181(gene name synonym)|uniprotkb:MAD1L1(gene name)|psi-mi:MAD1L1(display_short)|uniprotkb:MAD1(gene name synonym)|uniprotkb:TXBP181(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11540484|imex:IM-24995-1908	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009370.1|sgd:S000000030|ensemblfungi:YAL032C(gene)|ensemblfungi:YAL032C_mRNA(transcript)|go:"GO:0000350"(generation of catalytic spliceosome for second transesterification step)|go:"GO:0005634"(nucleus)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|interpro:IPR004015(SKIP/SNW)|interpro:IPR017862|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|dip:DIP-2774N|mint:P28004|sgd:YAL032C(identity)	refseq:NP_001013858.1|refseq:NP_001013859.1|refseq:NP_003541.2|refseq:NP_001291452.1|refseq:NP_001291453.1|ensembl:ENSG00000002822(gene)|ensembl:ENST00000265854(transcript)|go:"GO:0090235"(regulation of metaphase plate congression)|go:"GO:1902426"(deactivation of mitotic spindle assembly checkpoint)|interpro:IPR008672(Mitotic checkpoint)|mint:Q9Y6D9|rcsb pdb:1GO4|rcsb pdb:4DZO|rcsb pdb:7B1F|rcsb pdb:7B1H|rcsb pdb:7B1J|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|ensembl:ENST00000399654(transcript)|ensembl:ENST00000406869(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043515"(kinetochore binding)|go:"GO:0044615"(nuclear pore nuclear basket)|go:"GO:0048538"(thymus development)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0072686"(mitotic spindle)|refseq:XP_005249934.1|dip:DIP-29654N|entrezgene/locuslink:8379(identity)	-	crc64:FE5A724186D7FE84	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:qoHF1UsO3k+JOTOfigSuy2P84/k559292	rogid:9CcqpZlN0IgqC939rIo7vNgOvLQ9606	intact-crc:86CF26FF479D6475|rigid:kbuda1h/jrILQ/THd5wtekEKM/4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9Y3Q8	uniprotkb:P28004	intact:EBI-739485|uniprotkb:A8MWR6|ensembl:ENSP00000300181|uniprotkb:A4D2C3|uniprotkb:D6W5V9	intact:EBI-20640|uniprotkb:D6VPI6|ensemblfungi:YAL032C	psi-mi:t22d4_human(display_long)|uniprotkb:TSC22D4(gene name)|psi-mi:TSC22D4(display_short)|uniprotkb:TILZ2(gene name synonym)|uniprotkb:TSC22-related-inducible leucine zipper protein 2(gene name synonym)|uniprotkb:Tsc-22-like protein THG-1(gene name synonym)|uniprotkb:THG1(gene name synonym)	psi-mi:prp45_yeast(display_long)|uniprotkb:YAL032C(locus name)|uniprotkb:PRP45(gene name)|psi-mi:PRP45(display_short)|uniprotkb:FUN20(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11540475|imex:IM-24995-1907	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000166925(gene)|ensembl:ENST00000300181(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006970"(response to osmotic stress)|interpro:IPR000580(TSC-22 / Dip / Bun)|interpro:IPR042553|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|refseq:NP_112197.1|refseq:NP_001289972.1|entrezgene/locuslink:81628(identity)	refseq:NP_009370.1|sgd:S000000030|ensemblfungi:YAL032C(gene)|ensemblfungi:YAL032C_mRNA(transcript)|go:"GO:0000350"(generation of catalytic spliceosome for second transesterification step)|go:"GO:0005634"(nucleus)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|interpro:IPR004015(SKIP/SNW)|interpro:IPR017862|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|dip:DIP-2774N|mint:P28004|sgd:YAL032C(identity)	-	-	crc64:FE5A724186D7FE84	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:eL12cHY76zEPOXzT1HFKPSckS8Y9606	rogid:qoHF1UsO3k+JOTOfigSuy2P84/k559292	intact-crc:2E5E22ECD4FA976F|rigid:riVze4uPf7Sha0q+RYw99zeY8eI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UKT9	uniprotkb:P28004	intact:EBI-747204|uniprotkb:Q8WWQ9|uniprotkb:Q8WWR0|uniprotkb:Q8WWR1|uniprotkb:Q8WWR2|uniprotkb:Q8WWR3|uniprotkb:Q8N574|uniprotkb:B4DVV5|uniprotkb:Q69BL6|uniprotkb:Q69BL7|uniprotkb:Q69BL8|uniprotkb:Q69BL9|uniprotkb:Q69BM0|uniprotkb:Q69BM1|uniprotkb:Q69BM2|uniprotkb:Q69BM3|uniprotkb:Q69BM5|ensembl:ENSP00000344544	intact:EBI-20640|uniprotkb:D6VPI6|ensemblfungi:YAL032C	psi-mi:ikzf3_human(display_long)|uniprotkb:ZNFN1A3(gene name synonym)|uniprotkb:Ikaros family zinc finger protein 3(gene name synonym)|uniprotkb:IKZF3(gene name)|psi-mi:IKZF3(display_short)	psi-mi:prp45_yeast(display_long)|uniprotkb:YAL032C(locus name)|uniprotkb:PRP45(gene name)|psi-mi:PRP45(display_short)|uniprotkb:FUN20(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11540466|imex:IM-24995-1906	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001271443.1|refseq:NP_001271444.1|refseq:NP_036613.2|refseq:NP_899051.1|refseq:NP_899052.1|refseq:NP_899053.1|refseq:NP_899054.1|refseq:NP_899055.1|refseq:NP_001271445.1|refseq:NP_001244337.1|refseq:NP_001244338.1|refseq:NP_001244339.1|refseq:NP_001244340.1|refseq:NP_001244341.1|refseq:NP_001244342.1|refseq:NP_001244343.1|ensembl:ENSG00000161405(gene)|ensembl:ENST00000346872(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007498"(mesoderm development)|go:"GO:0009617"(response to bacterium)|go:"GO:0030888"(regulation of B cell proliferation)|go:"GO:0042113"(B cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045577"(regulation of B cell differentiation)|go:"GO:0045619"(regulation of lymphocyte differentiation)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|go:"GO:0046872"(metal ion binding)|dip:DIP-56975N|entrezgene/locuslink:22806(identity)	refseq:NP_009370.1|sgd:S000000030|ensemblfungi:YAL032C(gene)|ensemblfungi:YAL032C_mRNA(transcript)|go:"GO:0000350"(generation of catalytic spliceosome for second transesterification step)|go:"GO:0005634"(nucleus)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|interpro:IPR004015(SKIP/SNW)|interpro:IPR017862|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|dip:DIP-2774N|mint:P28004|sgd:YAL032C(identity)	-	-	crc64:FE5A724186D7FE84	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:2Kp6LefSLfK5VIiE6DmQusFIfMY9606	rogid:qoHF1UsO3k+JOTOfigSuy2P84/k559292	intact-crc:5588E730EEA3B49B|rigid:v6leynU3zaB55LIQL3Ag/PFxtks	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8N5R6	uniprotkb:P29703	intact:EBI-740841|intact:EBI-953781|uniprotkb:B3KQ49|uniprotkb:A8K3U4|uniprotkb:A8MPQ6|uniprotkb:A8MV61|uniprotkb:A8MVU9|uniprotkb:Q9H5Q6|uniprotkb:Q8TAX6|intact:EBI-2320546|intact:EBI-11522976	intact:EBI-14814|uniprotkb:D6VXR6|ensemblfungi:YKL019W	psi-mi:ccd33_human(display_long)|uniprotkb:CCDC33(gene name)|psi-mi:CCDC33(display_short)|uniprotkb:Cancer/testis antigen 61(gene name synonym)	psi-mi:fnta_yeast(display_long)|uniprotkb:YKL019W(locus name)|uniprotkb:RAM2(gene name)|psi-mi:RAM2(display_short)|uniprotkb:CAAX farnesyltransferase subunit alpha(gene name synonym)|uniprotkb:Ras proteins prenyltransferase subunit alpha(gene name synonym)|uniprotkb:FTase-alpha(gene name synonym)|uniprotkb:Type I protein geranyl-geranyltransferase subunit alpha(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11540538|imex:IM-24995-1914	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_079331.3|interpro:IPR000008(C2 calcium-dependent membrane targeting)|go:"GO:0005777"(peroxisome)|refseq:NP_001274110.1|refseq:NP_877592.2|mint:Q8N5R6|interpro:IPR035892|interpro:IPR039889|entrezgene/locuslink:80125(identity)	sgd:S000001502|refseq:NP_012906.3|go:"GO:0004662"(CAAX-protein geranylgeranyltransferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005953"(CAAX-protein geranylgeranyltransferase complex)|go:"GO:0005965"(protein farnesyltransferase complex)|go:"GO:0007323"(peptide pheromone maturation)|go:"GO:0018343"(protein farnesylation)|go:"GO:0018344"(protein geranylgeranylation)|interpro:IPR002088(Protein prenyltransferase, alpha subunit)|reactome:R-SCE-9648002|ensemblfungi:YKL019W(gene)|ensemblfungi:YKL019W_mRNA(transcript)|go:"GO:0004660"(protein farnesyltransferase activity)|go:"GO:0004661"(protein geranylgeranyltransferase activity)|dip:DIP-1233N|mint:P29703|sgd:YKL019W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2021/11/30	rogid:eEIn7pQyfdHWx8TeLJpYy0i/gww9606	rogid:u2rtpSuSW9Zd8LHWmniip7r5Ycs559292	intact-crc:B515D2F002B39BE7|rigid:eNKRXOiTEKxKnSyeUuxyrUsxuiE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96KN7-4	uniprotkb:P29461	intact:EBI-11525164|ensembl:ENSP00000372391	intact:EBI-14188|ensemblfungi:YOR208W|uniprotkb:D6W2R4	psi-mi:q96kn7-4(display_long)|uniprotkb:RPGRIP1(gene name)|psi-mi:RPGRIP1(display_short)	psi-mi:ptp2_yeast(display_long)|uniprotkb:Protein-tyrosine phosphatase 2(gene name synonym)|uniprotkb:PTP2(gene name)|psi-mi:PTP2(display_short)|uniprotkb:YOR208W(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11540529|imex:IM-24995-1913	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-1050213(isoform-parent)|ensembl:ENSG00000092200(gene)|ensembl:ENST00000382933(transcript)|uniprotkb:Q96KN7-4(isoform-parent)|entrezgene/locuslink:57096(identity)	sgd:S000005734|ensemblfungi:YOR208W(gene)|ensemblfungi:YOR208W_mRNA(transcript)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0043937"(regulation of sporulation)|go:"GO:0051457"(maintenance of protein location in nucleus)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|refseq:NP_014851.3|dip:DIP-2369N|sgd:YOR208W(identity)	-	-	crc64:1033D2F0AA23BD35	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Xy0433uM/nWhWLM/EsfESPJDIy49606	rogid:y6lL7sE5o4uuIJ2YtaKCUzxz8o0559292	intact-crc:93BEC0A227AB4831|rigid:sWHPGmW1pLVHtqfUvOASr//pG4M	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P29461	uniprotkb:P51116	intact:EBI-14188|ensemblfungi:YOR208W|uniprotkb:D6W2R4	intact:EBI-740459|uniprotkb:Q8WUM2|uniprotkb:Q86V09|uniprotkb:B2R9M2|uniprotkb:D3DTQ1|ensembl:ENSP00000250113	psi-mi:ptp2_yeast(display_long)|uniprotkb:Protein-tyrosine phosphatase 2(gene name synonym)|uniprotkb:PTP2(gene name)|psi-mi:PTP2(display_short)|uniprotkb:YOR208W(locus name)	psi-mi:fxr2_human(display_long)|uniprotkb:FXR2(gene name)|psi-mi:FXR2(display_short)|uniprotkb:FMR1L2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11540520|imex:IM-24995-1912	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005734|ensemblfungi:YOR208W(gene)|ensemblfungi:YOR208W_mRNA(transcript)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0043937"(regulation of sporulation)|go:"GO:0051457"(maintenance of protein location in nucleus)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|refseq:NP_014851.3|dip:DIP-2369N|sgd:YOR208W(identity)	interpro:IPR004087(K Homology)|refseq:NP_004851.2|ensembl:ENSG00000129245(gene)|ensembl:ENST00000250113(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0044326"(dendritic spine neck)|go:"GO:0045182"(translation regulator activity)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0098793"(presynapse)|go:"GO:1902737"(dendritic filopodium)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|interpro:IPR004088(K Homology, type 1)|interpro:IPR008395(Agenet)|interpro:IPR022034|interpro:IPR032172|interpro:IPR036612|interpro:IPR040148|interpro:IPR040472|interpro:IPR041560|mint:P51116|rcsb pdb:3H8Z|entrezgene/locuslink:9513(identity)	-	crc64:1033D2F0AA23BD35	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:y6lL7sE5o4uuIJ2YtaKCUzxz8o0559292	rogid:NnYgyzD2NRGIO1ZHukr5qy44qRE9606	intact-crc:93A2D169D20C2A7F|rigid:B5gDZeiWjPzPEo5bLYrloAF5b10	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P28777	uniprotkb:Q15025	intact:EBI-2906|uniprotkb:D6VU01|ensemblfungi:YGL148W	intact:EBI-357849|uniprotkb:A4F1W8|uniprotkb:O76008|uniprotkb:Q96EL9|uniprotkb:Q99833|uniprotkb:Q9H1J3|uniprotkb:B7Z699|uniprotkb:Q6N077|ensembl:ENSP00000317891|ensembl:ENSP00000428187|ensembl:ENSP00000430760|uniprotkb:A4F1W9|uniprotkb:A4F1X2|uniprotkb:A4F1X4|uniprotkb:A4F1X5|uniprotkb:A4F1X6|uniprotkb:A4F1X7|uniprotkb:A4F1X9|uniprotkb:E7EPY1|uniprotkb:E7ET96|uniprotkb:Q05KP3|uniprotkb:Q05KP4	psi-mi:aroc_yeast(display_long)|uniprotkb:ARO2(gene name)|psi-mi:ARO2(display_short)|uniprotkb:5-enolpyruvylshikimate-3-phosphate phospholyase(gene name synonym)|uniprotkb:YGL148W(locus name)	psi-mi:tnip1_human(display_long)|uniprotkb:TNIP1(gene name)|psi-mi:TNIP1(display_short)|uniprotkb:KIAA0113(gene name synonym)|uniprotkb:NAF1(gene name synonym)|uniprotkb:Nef-associated factor 1(gene name synonym)|uniprotkb:HIV-1 Nef-interacting protein(gene name synonym)|uniprotkb:Virion-associated nuclear shuttling protein(gene name synonym)|uniprotkb:Nip40-1(gene name synonym)|uniprotkb:A20-binding inhibitor of NF-kappa-B activation 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11540511|imex:IM-24995-1911	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011367.1|sgd:S000003116|dip:DIP-4219N|ensemblfungi:YGL148W(gene)|ensemblfungi:YGL148W_mRNA(transcript)|go:"GO:0004107"(chorismate synthase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008652"(cellular amino acid biosynthetic process)|go:"GO:0009073"(aromatic amino acid family biosynthetic process)|go:"GO:0009423"(chorismate biosynthetic process)|go:"GO:0010181"(FMN binding)|go:"GO:0042602"("riboflavin reductase (NADPH) activity")|interpro:IPR000453(Chorismate synthase)|interpro:IPR020541|interpro:IPR035904|rcsb pdb:1R52|rcsb pdb:1R53|sgd:YGL148W(identity)	refseq:NP_006049.3|refseq:NP_001239319.1|refseq:NP_001239320.1|refseq:NP_001239321.1|refseq:NP_001239322.1|refseq:NP_001245383.1|dip:DIP-27577N|refseq:NP_001239315.1|ensembl:ENSG00000145901(gene)|ensembl:ENST00000315050(transcript)|ensembl:ENST00000521591(transcript)|ensembl:ENST00000522226(transcript)|go:"GO:0002755"(MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0006952"(defense response)|go:"GO:0006954"(inflammatory response)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0009101"(glycoprotein biosynthetic process)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0085032"(modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade)|go:"GO:1903003"(positive regulation of protein deubiquitination)|interpro:IPR033372|mint:Q15025|reactome:R-HSA-5689896|go:"GO:0051019"(mitogen-activated protein kinase binding)|refseq:NP_001239314.1|refseq:NP_001245384.1|refseq:NP_001245385.1|refseq:XP_006714814.1|refseq:XP_006714815.1|entrezgene/locuslink:10318(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:JKW/ZDgiD3nPihuzkWGFypk8hlA559292	rogid:16Vjb5CuGTAbW2M22qbCxgXtV1o9606	intact-crc:8285FBE465B28E40|rigid:xb67E17xpRCwxPHLuS+ViVrLr2Y	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:A0A087X1U9	uniprotkb:P29703	intact:EBI-11525184|ensembl:ENSP00000484475	intact:EBI-14814|uniprotkb:D6VXR6|ensemblfungi:YKL019W	psi-mi:a0a087x1u9_human(display_long)|uniprotkb:GAK(gene name)|psi-mi:GAK(display_short)	psi-mi:fnta_yeast(display_long)|uniprotkb:YKL019W(locus name)|uniprotkb:RAM2(gene name)|psi-mi:RAM2(display_short)|uniprotkb:CAAX farnesyltransferase subunit alpha(gene name synonym)|uniprotkb:Ras proteins prenyltransferase subunit alpha(gene name synonym)|uniprotkb:FTase-alpha(gene name synonym)|uniprotkb:Type I protein geranyl-geranyltransferase subunit alpha(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11540547|imex:IM-24995-1915	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000178950(gene)|ensembl:ENST00000618573(transcript)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR036869|entrezgene/locuslink:2580(identity)	sgd:S000001502|refseq:NP_012906.3|go:"GO:0004662"(CAAX-protein geranylgeranyltransferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005953"(CAAX-protein geranylgeranyltransferase complex)|go:"GO:0005965"(protein farnesyltransferase complex)|go:"GO:0007323"(peptide pheromone maturation)|go:"GO:0018343"(protein farnesylation)|go:"GO:0018344"(protein geranylgeranylation)|interpro:IPR002088(Protein prenyltransferase, alpha subunit)|reactome:R-SCE-9648002|ensemblfungi:YKL019W(gene)|ensemblfungi:YKL019W_mRNA(transcript)|go:"GO:0004660"(protein farnesyltransferase activity)|go:"GO:0004661"(protein geranylgeranyltransferase activity)|dip:DIP-1233N|mint:P29703|sgd:YKL019W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:9cLiPH0B6Uj9kREXyEJ+0f2ZQWw9606	rogid:u2rtpSuSW9Zd8LHWmniip7r5Ycs559292	intact-crc:A0346E174FEA7313|rigid:3E6Ybvs/yLKLs7QpduyvkOxXCSA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9BTE3-2	uniprotkb:P30665	intact:EBI-9384556|ensembl:ENSP00000358073	intact:EBI-4326|uniprotkb:D6W429|ensemblfungi:YPR019W	psi-mi:q9bte3-2(display_long)|uniprotkb:MCMBP(gene name)|psi-mi:MCMBP(display_short)|uniprotkb:C10orf119(gene name synonym)	psi-mi:mcm4_yeast(display_long)|uniprotkb:MCM4(gene name)|psi-mi:MCM4(display_short)|uniprotkb:HCD21(gene name synonym)|uniprotkb:YPR019W(locus name)|uniprotkb:YP9531.13(orf name)|uniprotkb:CDC54(gene name synonym)|uniprotkb:Cell division control protein 54(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11540575|imex:IM-24995-1918	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-749378(isoform-parent)|uniprotkb:Q9BTE3-2(isoform-parent)|ensembl:ENSG00000197771(gene)|ensembl:ENST00000369077(transcript)|entrezgene/locuslink:79892(identity)	dip:DIP-2409N|refseq:NP_015344.1|sgd:S000006223|mint:P30665|ensemblfungi:YPR019W(gene)|ensemblfungi:YPR019W_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0033260"(nuclear DNA replication)|go:"GO:0034214"(protein hexamerization)|go:"GO:0042555"(MCM complex)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0071162"(CMG complex)|go:"GO:0097373"(MCM core complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902975"(mitotic DNA replication initiation)|interpro:IPR001208(MCM)|interpro:IPR008047(MCM protein 4)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR036388|interpro:IPR041562|rcsb pdb:3JA8|rcsb pdb:3JC5|rcsb pdb:3JC6|rcsb pdb:3JC7|rcsb pdb:5BK4|rcsb pdb:5U8S|rcsb pdb:5U8T|rcsb pdb:5V8F|rcsb pdb:5XF8|rcsb pdb:6EYC|rcsb pdb:6F0L|rcsb pdb:6HV9|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6RQC|rcsb pdb:6SKL|rcsb pdb:6SKO|rcsb pdb:6U0M|rcsb pdb:6WGF|rcsb pdb:6WGG|rcsb pdb:6WGI|reactome:R-SCE-68949|reactome:R-SCE-68962|reactome:R-SCE-69052|sgd:YPR019W(identity)	-	-	crc64:382D542AE38975E3	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:nJOq6jis1maK+M/X0TcR44HlxRw9606	rogid:KpsdSZBisjpmXnNAJTZncPINxYI559292	intact-crc:AAD7C1D006B7938A|rigid:YECPGzZy7IokEtBFfv3t22SmfDw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8NA61-2	uniprotkb:P29703	intact:EBI-11524851|ensembl:ENSP00000368249|ensembl:ENSP00000480148	intact:EBI-14814|uniprotkb:D6VXR6|ensemblfungi:YKL019W	psi-mi:q8na61-2(display_long)|uniprotkb:CBY2(gene name)|psi-mi:CBY2(display_short)|uniprotkb:SPERT(gene name synonym)|uniprotkb:Spermatid-associated protein(gene name synonym)	psi-mi:fnta_yeast(display_long)|uniprotkb:YKL019W(locus name)|uniprotkb:RAM2(gene name)|psi-mi:RAM2(display_short)|uniprotkb:CAAX farnesyltransferase subunit alpha(gene name synonym)|uniprotkb:Ras proteins prenyltransferase subunit alpha(gene name synonym)|uniprotkb:FTase-alpha(gene name synonym)|uniprotkb:Type I protein geranyl-geranyltransferase subunit alpha(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11540566|imex:IM-24995-1917	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-741724(isoform-parent)|ensembl:ENSG00000174015(gene)|ensembl:ENST00000378966(transcript)|ensembl:ENST00000610924(transcript)|uniprotkb:Q8NA61-2(isoform-parent)|entrezgene/locuslink:220082(identity)	sgd:S000001502|refseq:NP_012906.3|go:"GO:0004662"(CAAX-protein geranylgeranyltransferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005953"(CAAX-protein geranylgeranyltransferase complex)|go:"GO:0005965"(protein farnesyltransferase complex)|go:"GO:0007323"(peptide pheromone maturation)|go:"GO:0018343"(protein farnesylation)|go:"GO:0018344"(protein geranylgeranylation)|interpro:IPR002088(Protein prenyltransferase, alpha subunit)|reactome:R-SCE-9648002|ensemblfungi:YKL019W(gene)|ensemblfungi:YKL019W_mRNA(transcript)|go:"GO:0004660"(protein farnesyltransferase activity)|go:"GO:0004661"(protein geranylgeranyltransferase activity)|dip:DIP-1233N|mint:P29703|sgd:YKL019W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:SogYcXGGMYRYzB9xKC5o0pEtsDs9606	rogid:u2rtpSuSW9Zd8LHWmniip7r5Ycs559292	intact-crc:604A80D50763FC68|rigid:i4d4cxUdwD81HyA2LjGD4Qevni8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P29703	uniprotkb:Q15025	intact:EBI-14814|uniprotkb:D6VXR6|ensemblfungi:YKL019W	intact:EBI-357849|uniprotkb:A4F1W8|uniprotkb:O76008|uniprotkb:Q96EL9|uniprotkb:Q99833|uniprotkb:Q9H1J3|uniprotkb:B7Z699|uniprotkb:Q6N077|ensembl:ENSP00000317891|ensembl:ENSP00000428187|ensembl:ENSP00000430760|uniprotkb:A4F1W9|uniprotkb:A4F1X2|uniprotkb:A4F1X4|uniprotkb:A4F1X5|uniprotkb:A4F1X6|uniprotkb:A4F1X7|uniprotkb:A4F1X9|uniprotkb:E7EPY1|uniprotkb:E7ET96|uniprotkb:Q05KP3|uniprotkb:Q05KP4	psi-mi:fnta_yeast(display_long)|uniprotkb:YKL019W(locus name)|uniprotkb:RAM2(gene name)|psi-mi:RAM2(display_short)|uniprotkb:CAAX farnesyltransferase subunit alpha(gene name synonym)|uniprotkb:Ras proteins prenyltransferase subunit alpha(gene name synonym)|uniprotkb:FTase-alpha(gene name synonym)|uniprotkb:Type I protein geranyl-geranyltransferase subunit alpha(gene name synonym)	psi-mi:tnip1_human(display_long)|uniprotkb:TNIP1(gene name)|psi-mi:TNIP1(display_short)|uniprotkb:KIAA0113(gene name synonym)|uniprotkb:NAF1(gene name synonym)|uniprotkb:Nef-associated factor 1(gene name synonym)|uniprotkb:HIV-1 Nef-interacting protein(gene name synonym)|uniprotkb:Virion-associated nuclear shuttling protein(gene name synonym)|uniprotkb:Nip40-1(gene name synonym)|uniprotkb:A20-binding inhibitor of NF-kappa-B activation 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11540556|imex:IM-24995-1916	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000001502|refseq:NP_012906.3|go:"GO:0004662"(CAAX-protein geranylgeranyltransferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005953"(CAAX-protein geranylgeranyltransferase complex)|go:"GO:0005965"(protein farnesyltransferase complex)|go:"GO:0007323"(peptide pheromone maturation)|go:"GO:0018343"(protein farnesylation)|go:"GO:0018344"(protein geranylgeranylation)|interpro:IPR002088(Protein prenyltransferase, alpha subunit)|reactome:R-SCE-9648002|ensemblfungi:YKL019W(gene)|ensemblfungi:YKL019W_mRNA(transcript)|go:"GO:0004660"(protein farnesyltransferase activity)|go:"GO:0004661"(protein geranylgeranyltransferase activity)|dip:DIP-1233N|mint:P29703|sgd:YKL019W(identity)	refseq:NP_006049.3|refseq:NP_001239319.1|refseq:NP_001239320.1|refseq:NP_001239321.1|refseq:NP_001239322.1|refseq:NP_001245383.1|dip:DIP-27577N|refseq:NP_001239315.1|ensembl:ENSG00000145901(gene)|ensembl:ENST00000315050(transcript)|ensembl:ENST00000521591(transcript)|ensembl:ENST00000522226(transcript)|go:"GO:0002755"(MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0006952"(defense response)|go:"GO:0006954"(inflammatory response)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0009101"(glycoprotein biosynthetic process)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0085032"(modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade)|go:"GO:1903003"(positive regulation of protein deubiquitination)|interpro:IPR033372|mint:Q15025|reactome:R-HSA-5689896|go:"GO:0051019"(mitogen-activated protein kinase binding)|refseq:NP_001239314.1|refseq:NP_001245384.1|refseq:NP_001245385.1|refseq:XP_006714814.1|refseq:XP_006714815.1|entrezgene/locuslink:10318(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:u2rtpSuSW9Zd8LHWmniip7r5Ycs559292	rogid:16Vjb5CuGTAbW2M22qbCxgXtV1o9606	intact-crc:608D2FBC311077AA|rigid:sQJPT1NPCq43/Y+YRi9FtfmfISo	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32335	uniprotkb:A0A0C4DGF1	intact:EBI-11318|uniprotkb:D6VYK4|ensemblfungi:YLR203C	intact:EBI-10188476|ensembl:ENSP00000433657	psi-mi:mss51_yeast(display_long)|uniprotkb:MSS51(gene name)|psi-mi:MSS51(display_short)|uniprotkb:YLR203C(locus name)|uniprotkb:L8167.17(orf name)|uniprotkb:Mitochondrial splicing suppressor protein 51(gene name synonym)	psi-mi:a0a0c4dgf1_human(display_long)|uniprotkb:ZBTB32(gene name)|psi-mi:ZBTB32(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11540620|imex:IM-24995-1923	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YLR203C(gene)|ensemblfungi:YLR203C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0031314"(extrinsic component of mitochondrial inner membrane)|go:"GO:0033617"(mitochondrial cytochrome c oxidase assembly)|go:"GO:0045182"(translation regulator activity)|go:"GO:0070131"(positive regulation of mitochondrial translation)|interpro:IPR032717|interpro:IPR013272(YL1 nuclear, C-terminal)|sgd:S000004193|refseq:NP_013304.1|mint:P32335|dip:DIP-4602N|sgd:YLR203C(identity)	interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|ensembl:ENSG00000011590(gene)|ensembl:ENST00000481182(transcript)|go:"GO:0042802"(identical protein binding)|entrezgene/locuslink:27033(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:ytfyoVVQ1W2FaXmytaIbaxZyYjE559292	rogid:w3k7YT4kw/T+Xi5YBqGHSpHtwMM9606	intact-crc:B9034BBDCC64BE86|rigid:9Z3qT3qmv5F1QZq68kZv2HPQHhk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P31412	uniprotkb:Q96CN9	intact:EBI-20260|uniprotkb:D6VXK7|ensemblfungi:YKL080W	intact:EBI-746252|uniprotkb:Q9H6N7|ensembl:ENSP00000318821	psi-mi:vatc_yeast(display_long)|uniprotkb:VMA5(gene name)|psi-mi:VMA5(display_short)|uniprotkb:VAT3(gene name synonym)|uniprotkb:VATC(gene name synonym)|uniprotkb:YKL410(orf name)|uniprotkb:YKL080W(locus name)|uniprotkb:Vacuolar proton pump subunit C(gene name synonym)|uniprotkb:V-ATPase 42 kDa subunit(gene name synonym)	psi-mi:gcc1_human(display_long)|uniprotkb:Golgi coiled-coil protein 1(gene name synonym)|uniprotkb:GCC1(gene name)|psi-mi:GCC1(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11540611|imex:IM-24995-1922	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012843.1|sgd:S000001563|ensemblfungi:YKL080W(gene)|ensemblfungi:YKL080W_mRNA(transcript)|go:"GO:0000221"(vacuolar proton-transporting V-type ATPase, V1 domain)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005524"(ATP binding)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|interpro:IPR004907(ATPase, V1 complex, subunit C)|interpro:IPR036132|rcsb pdb:1U7L|rcsb pdb:3J9T|rcsb pdb:3J9U|rcsb pdb:3J9V|rcsb pdb:4DL0|rcsb pdb:4EFA|rcsb pdb:5VOX|rcsb pdb:5VOY|rcsb pdb:5VOZ|rcsb pdb:6O7V|rcsb pdb:6O7W|rcsb pdb:6O7X|reactome:R-SCE-1222556|reactome:R-SCE-77387|reactome:R-SCE-917977|reactome:R-SCE-9639288|dip:DIP-4701N|mint:P31412|sgd:YKL080W(identity)	refseq:NP_078799.2|ensembl:ENSG00000179562(gene)|ensembl:ENST00000321407(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0031267"(small GTPase binding)|interpro:IPR000237(GRIP)|reactome:R-HSA-6811440|go:"GO:0000138"(Golgi trans cisterna)|entrezgene/locuslink:79571(identity)	-	crc64:0CD1B814046C377E	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:NBI0upCB5yxAyMQgccBcLhjZk8s559292	rogid:SCI+peKjPIvl/HbUUpHGM++qiRE9606	intact-crc:B5F4EC174F96BBF5|rigid:RtDrn9y+os/mkYe0mRZfc8/yjS8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P31384	uniprotkb:Q9UFF9	intact:EBI-4396|uniprotkb:D6VPJ7|ensemblfungi:YAL021C	intact:EBI-742299|uniprotkb:O95709|uniprotkb:Q7Z521|uniprotkb:Q9H6Y1|uniprotkb:D3DQI8|uniprotkb:B2RAR8|intact:EBI-10979182|uniprotkb:B0AZS3|uniprotkb:B7Z8R1|ensembl:ENSP00000285896|ensembl:ENSP00000384747|ensembl:ENSP00000430493	psi-mi:ccr4_yeast(display_long)|uniprotkb:CCR4(gene name)|psi-mi:CCR4(display_short)|uniprotkb:Carbon catabolite repressor protein 4(gene name synonym)|uniprotkb:Cytoplasmic deadenylase(gene name synonym)|uniprotkb:Glucose-repressible alcohol dehydrogenase transcriptional effector(gene name synonym)|uniprotkb:FUN27(orf name)|uniprotkb:YAL021C(locus name)	psi-mi:cnot8_human(display_long)|uniprotkb:CNOT8(gene name)|psi-mi:CNOT8(display_short)|uniprotkb:CALIF(gene name synonym)|uniprotkb:POP2(gene name synonym)|uniprotkb:CCR4-associated factor 8(gene name synonym)|uniprotkb:CAF1-like protein(gene name synonym)|uniprotkb:CAF2(gene name synonym)|uniprotkb:Caf1b(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11540602|imex:IM-24995-1921	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009381.1|sgd:S000000019|dip:DIP-2522N|mint:P31384|ensemblfungi:YAL021C(gene)|ensemblfungi:YAL021C_mRNA(transcript)|go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0004535"("poly(A)-specific ribonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0007089"(traversing start control point of mitotic cell cycle)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0046872"(metal ion binding)|go:"GO:0048478"(replication fork protection)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR005135(Endonuclease/exonuclease/phosphatase)|interpro:IPR025875|interpro:IPR032675|interpro:IPR036691|rcsb pdb:4B8C|sgd:YAL021C(identity)	refseq:NP_004770.4|refseq:XP_005268584.1|refseq:NP_001288002.1|refseq:NP_001288003.1|refseq:NP_001288004.1|refseq:NP_001288006.1|refseq:NP_001288009.1|refseq:NP_001288011.1|refseq:NP_001288012.1|refseq:NP_001288015.1|refseq:XP_011536008.1|refseq:XP_011536010.1|refseq:XP_016865537.1|refseq:XP_016865538.1|refseq:XP_016865539.1|refseq:XP_016865540.1|refseq:XP_016865541.1|refseq:XP_016865542.1|refseq:XP_016865543.1|refseq:XP_016865544.1|refseq:XP_016865545.1|refseq:XP_016865546.1|ensembl:ENSG00000155508(gene)|ensembl:ENST00000285896(transcript)|ensembl:ENST00000403027(transcript)|ensembl:ENST00000517876(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0004535"("poly(A)-specific ribonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0035195"(gene silencing by miRNA)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0046872"(metal ion binding)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|interpro:IPR006941(Ribonuclease CAF1)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR027212|interpro:IPR036397|interpro:IPR039637|mint:Q9UFF9|reactome:R-HSA-429947|reactome:R-HSA-6804115|dip:DIP-29084N|entrezgene/locuslink:9337(identity)	-	crc64:5CDB2E8FEDDBEF6F	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:f5gxp32WdxKuHQnE8O9/EhhA3Gw559292	rogid:pjaQYzYBGJWC7z5R5s8Te+v2sRA9606	intact-crc:925AB46B37B9DB58|rigid:gFrxQ5V6bJZQ9MZJK/RYIsyvq/U	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P37198	uniprotkb:P31384	intact:EBI-347978|intact:EBI-28983799|ensembl:ENSP00000305503|ensembl:ENSP00000407331|ensembl:ENSP00000471191|ensembl:ENSP00000473192|uniprotkb:Q6GTM2|uniprotkb:Q503A4|uniprotkb:Q96C43|uniprotkb:Q9NSL1|uniprotkb:B3KWU5	intact:EBI-4396|uniprotkb:D6VPJ7|ensemblfungi:YAL021C	psi-mi:nup62_human(display_long)|uniprotkb:NUP62(gene name)|psi-mi:NUP62(display_short)|uniprotkb:62 kDa nucleoporin(gene name synonym)|uniprotkb:Nucleoporin Nup62(gene name synonym)	psi-mi:ccr4_yeast(display_long)|uniprotkb:CCR4(gene name)|psi-mi:CCR4(display_short)|uniprotkb:Carbon catabolite repressor protein 4(gene name synonym)|uniprotkb:Cytoplasmic deadenylase(gene name synonym)|uniprotkb:Glucose-repressible alcohol dehydrogenase transcriptional effector(gene name synonym)|uniprotkb:FUN27(orf name)|uniprotkb:YAL021C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11540593|imex:IM-24995-1920	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_714941.1|ensembl:ENSG00000213024(gene)|ensembl:ENST00000352066(transcript)|ensembl:ENST00000422090(transcript)|ensembl:ENST00000596217(transcript)|ensembl:ENST00000597029(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005642"(annulate lamellae)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007100"(mitotic centrosome separation)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007569"(cell aging)|go:"GO:0008219"(cell death)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0003682"(chromatin binding)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0019894"(kinesin binding)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042306"(regulation of protein import into nucleus)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043069"(negative regulation of programmed cell death)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045742"(positive regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046578"(regulation of Ras protein signal transduction)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0046601"(positive regulation of centriole replication)|go:"GO:0051028"(mRNA transport)|go:"GO:0051425"(PTB domain binding)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0072686"(mitotic spindle)|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|go:"GO:0090543"(Flemming body)|go:"GO:0098534"(centriole assembly)|go:"GO:1903438"(positive regulation of mitotic cytokinetic process)|go:"GO:1904781"(positive regulation of protein localization to centrosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR007758(Nucleoporin, Nsp1-like, C-terminal)|interpro:IPR026010|interpro:IPR033072|mint:P37198|rcsb pdb:2H4D|rcsb pdb:5IJN|rcsb pdb:5IJO|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|refseq:NP_714940.1|refseq:NP_001180286.1|refseq:NP_036478.2|refseq:NP_057637.2|ensembl:ENSP00000305503|ensembl:ENSP00000407331|ensembl:ENSP00000471191|ensembl:ENSP00000473192|dip:DIP-29749N|entrezgene/locuslink:23636(identity)	refseq:NP_009381.1|sgd:S000000019|dip:DIP-2522N|mint:P31384|ensemblfungi:YAL021C(gene)|ensemblfungi:YAL021C_mRNA(transcript)|go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0004535"("poly(A)-specific ribonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0007089"(traversing start control point of mitotic cell cycle)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0046872"(metal ion binding)|go:"GO:0048478"(replication fork protection)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR005135(Endonuclease/exonuclease/phosphatase)|interpro:IPR025875|interpro:IPR032675|interpro:IPR036691|rcsb pdb:4B8C|sgd:YAL021C(identity)	-	-	crc64:5CDB2E8FEDDBEF6F	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:v7mvKvTtVEnLMwcpUZIcdAzge009606	rogid:f5gxp32WdxKuHQnE8O9/EhhA3Gw559292	intact-crc:51795CB1B5F5E917|rigid:LxPYRKS68Nq0z2/lCQwYo7kiCB4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96IQ6	uniprotkb:P31384	intact:EBI-10295632|intact:EBI-11525227	intact:EBI-4396|uniprotkb:D6VPJ7|ensemblfungi:YAL021C	psi-mi:q96iq6_human(display_long)|uniprotkb:CCR4-associated factor 1(gene name synonym)	psi-mi:ccr4_yeast(display_long)|uniprotkb:CCR4(gene name)|psi-mi:CCR4(display_short)|uniprotkb:Carbon catabolite repressor protein 4(gene name synonym)|uniprotkb:Cytoplasmic deadenylase(gene name synonym)|uniprotkb:Glucose-repressible alcohol dehydrogenase transcriptional effector(gene name synonym)|uniprotkb:FUN27(orf name)|uniprotkb:YAL021C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11540584|imex:IM-24995-1919	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR039636|interpro:IPR039637|refseq:NP_001309019.1|refseq:NP_001309020.1|refseq:NP_001309021.1|refseq:NP_001309022.1|interpro:IPR006941(Ribonuclease CAF1)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|refseq:NP_001309023.1|refseq:NP_001309024.1|refseq:NP_001309025.1|refseq:NP_001309026.1|refseq:NP_037486.2|go:"GO:0003676"(nucleic acid binding)|go:"GO:0004535"("poly(A)-specific ribonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006417"(regulation of translation)|go:"GO:0030014"(CCR4-NOT complex)|interpro:IPR036397|entrezgene/locuslink:29883(identity)	refseq:NP_009381.1|sgd:S000000019|dip:DIP-2522N|mint:P31384|ensemblfungi:YAL021C(gene)|ensemblfungi:YAL021C_mRNA(transcript)|go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0004535"("poly(A)-specific ribonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0007089"(traversing start control point of mitotic cell cycle)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0046872"(metal ion binding)|go:"GO:0048478"(replication fork protection)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR005135(Endonuclease/exonuclease/phosphatase)|interpro:IPR025875|interpro:IPR032675|interpro:IPR036691|rcsb pdb:4B8C|sgd:YAL021C(identity)	-	-	crc64:5CDB2E8FEDDBEF6F	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/17	rogid:nAvs1jhkGYxf7NZ456rj5p+imsI9606	rogid:f5gxp32WdxKuHQnE8O9/EhhA3Gw559292	intact-crc:40286657D91D70B7|rigid:1icdiwmRVXf6zQNT9XI8W2lxTWU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q08379	uniprotkb:P32354	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	intact:EBI-5965|uniprotkb:D6VVD7|ensemblfungi:YIL150C	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:mcm10_yeast(display_long)|uniprotkb:YIL150C(locus name)|uniprotkb:MCM10(gene name)|psi-mi:MCM10(display_short)|uniprotkb:DNA43(gene name synonym)|uniprotkb:Protein DNA43(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11540649|imex:IM-24995-1926	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N|entrezgene/locuslink:2801(identity)	refseq:NP_012116.1|sgd:S000001412|dip:DIP-1293N|mint:P32354|ensemblfungi:YIL150C(gene)|ensemblfungi:YIL150C_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005657"(replication fork)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006348"|go:"GO:0007049"(cell cycle)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0046872"(metal ion binding)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR015408(Zinc finger, Mcm10/DnaG-type)|interpro:IPR040184|reactome:R-SCE-68962|sgd:YIL150C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2017/05/26	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	rogid:D2K/tLON/CnIcTTqkAQOdTZrRlg559292	intact-crc:4DC1808C744699A0|rigid:+7ogc9529UUncV4bIF3BqIxIVco	false	sufficient binding region:383-1002	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32342	uniprotkb:Q9H190	intact:EBI-17984|uniprotkb:D6VXG8|ensemblfungi:YKL122C	intact:EBI-742426|ensembl:ENSP00000371233|uniprotkb:O95892|uniprotkb:Q5W0X1|uniprotkb:Q9BZ42|uniprotkb:Q9H567|uniprotkb:Q9NRY8|intact:EBI-28983470|ensembl:ENSP00000342935|ensembl:ENSP00000354013	psi-mi:srp21_yeast(display_long)|uniprotkb:SRP21(gene name)|psi-mi:SRP21(display_short)|uniprotkb:YKL122C(locus name)|uniprotkb:YKL527(orf name)|uniprotkb:Signal recognition particle 21 kDa protein(gene name synonym)	psi-mi:sdcb2_human(display_long)|uniprotkb:Similar to TACIP18(gene name synonym)|uniprotkb:SDCBP2(gene name)|psi-mi:SDCBP2(display_short)|uniprotkb:SITAC18(gene name synonym)|uniprotkb:Syndecan-binding protein 2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11540640|imex:IM-24995-1925	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012800.1|sgd:S000001605|ensemblfungi:YKL122C(gene)|ensemblfungi:YKL122C_mRNA(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005786"(signal recognition particle, endoplasmic reticulum targeting)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|interpro:IPR039432|reactome:R-SCE-1799339|dip:DIP-4863N|mint:P32342|sgd:YKL122C(identity)	refseq:NP_001186713.1|refseq:NP_056500.2|refseq:NP_536737.3|ensembl:ENSP00000342935|ensembl:ENSP00000354013|ensembl:ENST00000381808|ensembl:ENSP00000371229|ensembl:ENSP00000371233|ensembl:ENSG00000125775(gene)|ensembl:ENST00000360779(transcript)|ensembl:ENST00000381812(transcript)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007399"(nervous system development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016607"(nuclear speck)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046907"(intracellular transport)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036034|interpro:IPR041489|ensembl:ENST00000339987(transcript)|entrezgene/locuslink:27111(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:UXyZkJvr4xO44RgYpDeA8lsND/k559292	rogid:vlEtVZkwLTte5PJ4i8ce+SwE/4Y9606	intact-crc:2CF97BC5E8714E88|rigid:aHpe/9H37iI703H7ZyZKFbRzWX8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q08379	uniprotkb:P32335	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	intact:EBI-11318|uniprotkb:D6VYK4|ensemblfungi:YLR203C	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:mss51_yeast(display_long)|uniprotkb:MSS51(gene name)|psi-mi:MSS51(display_short)|uniprotkb:YLR203C(locus name)|uniprotkb:L8167.17(orf name)|uniprotkb:Mitochondrial splicing suppressor protein 51(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11540629|imex:IM-24995-1924	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N|entrezgene/locuslink:2801(identity)	ensemblfungi:YLR203C(gene)|ensemblfungi:YLR203C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0031314"(extrinsic component of mitochondrial inner membrane)|go:"GO:0033617"(mitochondrial cytochrome c oxidase assembly)|go:"GO:0045182"(translation regulator activity)|go:"GO:0070131"(positive regulation of mitochondrial translation)|interpro:IPR032717|interpro:IPR013272(YL1 nuclear, C-terminal)|sgd:S000004193|refseq:NP_013304.1|mint:P32335|dip:DIP-4602N|sgd:YLR203C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2017/05/26	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	rogid:ytfyoVVQ1W2FaXmytaIbaxZyYjE559292	intact-crc:CAE3F8E53852D776|rigid:cV+qhCKhh9qPlAq6QOMTwpceMzI	false	sufficient binding region:383-1002	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32453	uniprotkb:Q15041	intact:EBI-3306|uniprotkb:D6W0N0|ensemblfungi:YNL315C	intact:EBI-714543|ensembl:ENSP00000306788|uniprotkb:B7Z6S5|uniprotkb:B7Z791|uniprotkb:F5GXP4	psi-mi:atp11_yeast(display_long)|uniprotkb:ATP11(gene name)|psi-mi:ATP11(display_short)|uniprotkb:N0357(orf name)|uniprotkb:YNL315C(locus name)	psi-mi:ar6p1_human(display_long)|uniprotkb:ARL6IP(gene name synonym)|uniprotkb:ARL6IP1(gene name)|psi-mi:ARL6IP1(display_short)|uniprotkb:KIAA0069(gene name synonym)|uniprotkb:ARMER(gene name synonym)|uniprotkb:Apoptotic regulator in the membrane of the endoplasmic reticulum(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11540687|imex:IM-24995-1930	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014084.1|sgd:S000005259|dip:DIP-3026N|mint:P32453|ensemblfungi:YNL315C(gene)|ensemblfungi:YNL315C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0033615"(mitochondrial proton-transporting ATP synthase complex assembly)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR010591(ATP11)|sgd:YNL315C(identity)	refseq:NP_055976.1|ensembl:ENSG00000170540(gene)|ensembl:ENST00000304414(transcript)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006613"(cotranslational protein targeting to membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0071787"(endoplasmic reticulum tubular network formation)|go:"GO:1903371"(regulation of endoplasmic reticulum tubular network organization)|go:"GO:1990809"(endoplasmic reticulum tubular network membrane organization)|interpro:IPR033301|mint:Q15041|go:"GO:0002038"(positive regulation of L-glutamate import across plasma membrane)|refseq:NP_001300787.1|entrezgene/locuslink:23204(identity)	-	crc64:61109AA4D338F2CD	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:JsQu6HtKtGqAVhHzaPVc8IMYdqM559292	rogid:3fjkoyvUx25po7xsPcXgpjEeLJg9606	intact-crc:1B5970B46361130A|rigid:yyzxtYV9KcvFNA2QogAC0WqTvFY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32449	uniprotkb:P35520	intact:EBI-2915|uniprotkb:D6VQP5|ensemblfungi:YBR249C	intact:EBI-740135|uniprotkb:Q99425|uniprotkb:Q9BWC5|uniprotkb:B2R993|uniprotkb:D3DSK4|intact:EBI-14245939|ensembl:ENSP00000344460|ensembl:ENSP00000352643|ensembl:ENSP00000381225|ensembl:ENSP00000381231	psi-mi:arog_yeast(display_long)|uniprotkb:ARO4(gene name)|psi-mi:ARO4(display_short)|uniprotkb:YBR249C(locus name)|uniprotkb:YBR1701(orf name)|uniprotkb:Phospho-2-keto-3-deoxyheptonate aldolase(gene name synonym)|uniprotkb:3-deoxy-D-arabino-heptulosonate 7-phosphate synthase(gene name synonym)|uniprotkb:DAHP synthase(gene name synonym)	psi-mi:cbs_human(display_long)|uniprotkb:CBS(gene name)|psi-mi:CBS(display_short)|uniprotkb:Serine sulfhydrase(gene name synonym)|uniprotkb:Beta-thionase(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11540678|imex:IM-24995-1929	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009808.1|sgd:S000000453|dip:DIP-4175N|mint:P32449|ensemblfungi:YBR249C(gene)|ensemblfungi:YBR249C_mRNA(transcript)|go:"GO:0003849"(3-deoxy-7-phosphoheptulonate synthase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008652"(cellular amino acid biosynthetic process)|go:"GO:0009073"(aromatic amino acid family biosynthetic process)|go:"GO:0009423"(chorismate biosynthetic process)|interpro:IPR006218(DAHP synthetase I/KDSA)|interpro:IPR006219(DHAP synthase, class 1)|interpro:IPR013785(Aldolase-type TIM barrel)|rcsb pdb:1HFB|rcsb pdb:1OAB|rcsb pdb:1OF6|rcsb pdb:1OF8|rcsb pdb:1OFA|rcsb pdb:1OFB|rcsb pdb:1OFO|rcsb pdb:1OFP|rcsb pdb:1OFQ|rcsb pdb:1OFR|rcsb pdb:1OG0|sgd:YBR249C(identity)	refseq:NP_000062.1|refseq:NP_001171479.1|refseq:NP_001171480.1|ensembl:ENSG00000160200(gene)|ensembl:ENST00000352178(transcript)|ensembl:ENST00000359624(transcript)|ensembl:ENST00000398158(transcript)|go:"GO:0004122"(cystathionine beta-synthase activity)|ensembl:ENST00000398165(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006535"(cysteine biosynthetic process from serine)|go:"GO:0006563"(L-serine metabolic process)|go:"GO:0006565"(L-serine catabolic process)|go:"GO:0019343"(cysteine biosynthetic process via cystathionine)|go:"GO:0019344"(cysteine biosynthetic process)|go:"GO:0019346"(transsulfuration)|go:"GO:0019448"(L-cysteine catabolic process)|go:"GO:0019825"(oxygen binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0020037"(heme binding)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042262"(DNA protection)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043418"(homocysteine catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0050421"("nitrite reductase (NO-forming) activity")|go:"GO:0050667"(homocysteine metabolic process)|go:"GO:0070025"(carbon monoxide binding)|go:"GO:0070026"(nitric oxide binding)|go:"GO:0070814"(hydrogen sulfide biosynthetic process)|go:"GO:0072341"(modified amino acid binding)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR001216(Cysteine synthase/cystathionine beta-synthase P-phosphate-binding site)|interpro:IPR001926(Pyridoxal phosphate-dependent enzyme, beta subunit)|interpro:IPR005857(Cystathionine beta-synthase)|interpro:IPR036052|mint:P35520|rcsb pdb:1JBQ|rcsb pdb:1M54|rcsb pdb:4COO|rcsb pdb:4L0D|rcsb pdb:4L27|rcsb pdb:4L28|rcsb pdb:4L3V|rcsb pdb:4PCU|rcsb pdb:4UUU|rcsb pdb:5MMS|reactome:R-HSA-1614603|reactome:R-HSA-2408508|refseq:XP_011528079.1|refseq:XP_011528083.1|refseq:XP_011528084.1|refseq:XP_011544396.1|refseq:XP_011544397.1|refseq:XP_011544399.1|refseq:XP_011544400.1|refseq:XP_011544401.1|refseq:NP_001307227.1|refseq:NP_001308002.1|refseq:XP_016883700.1|refseq:XP_016883701.1|refseq:XP_016883702.1|refseq:XP_016883703.1|refseq:XP_016883704.1|refseq:XP_016883705.1|refseq:XP_016883706.1|refseq:XP_016883707.1|refseq:XP_016883978.1|refseq:XP_016883979.1|refseq:XP_016883980.1|refseq:XP_016883981.1|entrezgene/locuslink:875(identity)	-	crc64:594ED48F24175979	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:y1YXaSHJozc5Q77Q8LqQ61IA6Lw559292	rogid:f9eo0cPOHppVY7Nqejag3YyK18s9606	intact-crc:BBE0F542AB86EDE5|rigid:ZtvOayfnVEJ2d3guFmvfzRJhXps	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8IZ13	uniprotkb:P32381	intact:EBI-7186123|ensembl:ENSP00000386184|ensembl:ENSP00000428831|uniprotkb:Q9H5S8|uniprotkb:D3DQJ9|intact:MINT-8163956|intact:MINT-8247520|uniprotkb:Q9UH87	intact:EBI-2927|uniprotkb:D6VRW3|ensemblfungi:YDL029W	psi-mi:zbed8_human(display_long)|uniprotkb:ZBED8(gene name)|psi-mi:ZBED8(display_short)|uniprotkb:Buster3(gene name synonym)|uniprotkb:C5orf54(gene name synonym)|uniprotkb:Transposon-derived Buster3 transposase-like protein(gene name synonym)|uniprotkb:Zinc finger BED domain-containing protein 8(gene name synonym)	psi-mi:arp2_yeast(display_long)|uniprotkb:ACT2(gene name synonym)|uniprotkb:YDL029W(locus name)|uniprotkb:D2778(orf name)|uniprotkb:ARP2(gene name)|psi-mi:ARP2(display_short)|uniprotkb:Actin-like protein ARP2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11540669|imex:IM-24995-1928	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001290180.1|ensembl:ENSG00000221886(gene)|ensembl:ENST00000408953(transcript)|ensembl:ENST00000523213(transcript)|go:"GO:0005654"(nucleoplasm)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR025398|mint:Q8IZ13|refseq:NP_071373.2|entrezgene/locuslink:63920(identity)	refseq:NP_010255.1|sgd:S000002187|dip:DIP-2217N|mint:P32381|ensemblfungi:YDL029W(gene)|ensemblfungi:YDL029W_mRNA(transcript)|go:"GO:0000001"(mitochondrion inheritance)|go:"GO:0003779"(actin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0030476"(ascospore wall assembly)|go:"GO:0030479"(actin cortical patch)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0044396"(actin cortical patch organization)|go:"GO:0051654"(establishment of mitochondrion localization)|interpro:IPR004000(Actin/actin-like)|interpro:IPR020902|interpro:IPR043129|reactome:R-SCE-2029482|reactome:R-SCE-5663213|reactome:R-SCE-6798695|reactome:R-SCE-8856828|sgd:YDL029W(identity)	-	comment:mint	crc64:4C9E8952B477A1B9	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:UMQXSqCyTL0MlOJybHaWQazjfPg9606	rogid:baSDcw/PZH3Z8YHhIcYqtlNO3mw559292	intact-crc:FA3021A4DDE1A409|rigid:6GEbCj29ogHagPn37NpLBoQxNaw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32354	uniprotkb:P51116	intact:EBI-5965|uniprotkb:D6VVD7|ensemblfungi:YIL150C	intact:EBI-740459|uniprotkb:Q8WUM2|uniprotkb:Q86V09|uniprotkb:B2R9M2|uniprotkb:D3DTQ1|ensembl:ENSP00000250113	psi-mi:mcm10_yeast(display_long)|uniprotkb:YIL150C(locus name)|uniprotkb:MCM10(gene name)|psi-mi:MCM10(display_short)|uniprotkb:DNA43(gene name synonym)|uniprotkb:Protein DNA43(gene name synonym)	psi-mi:fxr2_human(display_long)|uniprotkb:FXR2(gene name)|psi-mi:FXR2(display_short)|uniprotkb:FMR1L2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11540660|imex:IM-24995-1927	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012116.1|sgd:S000001412|dip:DIP-1293N|mint:P32354|ensemblfungi:YIL150C(gene)|ensemblfungi:YIL150C_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005657"(replication fork)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006348"|go:"GO:0007049"(cell cycle)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0046872"(metal ion binding)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR015408(Zinc finger, Mcm10/DnaG-type)|interpro:IPR040184|reactome:R-SCE-68962|sgd:YIL150C(identity)	interpro:IPR004087(K Homology)|refseq:NP_004851.2|ensembl:ENSG00000129245(gene)|ensembl:ENST00000250113(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0044326"(dendritic spine neck)|go:"GO:0045182"(translation regulator activity)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0098793"(presynapse)|go:"GO:1902737"(dendritic filopodium)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|interpro:IPR004088(K Homology, type 1)|interpro:IPR008395(Agenet)|interpro:IPR022034|interpro:IPR032172|interpro:IPR036612|interpro:IPR040148|interpro:IPR040472|interpro:IPR041560|mint:P51116|rcsb pdb:3H8Z|entrezgene/locuslink:9513(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:D2K/tLON/CnIcTTqkAQOdTZrRlg559292	rogid:NnYgyzD2NRGIO1ZHukr5qy44qRE9606	intact-crc:A92D83EB07E2C79D|rigid:+bhE3w6I1kpJayBmaB4tg0UDEQ0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96DZ9-2	uniprotkb:P32453	intact:EBI-11522780|ensembl:ENSP00000352270|ensembl:ENSP00000497215	intact:EBI-3306|uniprotkb:D6W0N0|ensemblfungi:YNL315C	psi-mi:q96dz9-2(display_long)|uniprotkb:CMTM5(gene name)|psi-mi:CMTM5(display_short)|uniprotkb:CKLFSF5(gene name synonym)|uniprotkb:Chemokine-like factor superfamily member 5(gene name synonym)	psi-mi:atp11_yeast(display_long)|uniprotkb:ATP11(gene name)|psi-mi:ATP11(display_short)|uniprotkb:N0357(orf name)|uniprotkb:YNL315C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11540723|imex:IM-24995-1934	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000166091(gene)|ensembl:ENST00000359320(transcript)|ensembl:ENST00000649278(transcript)|intact:EBI-2548702(isoform-parent)|uniprotkb:Q96DZ9-2(isoform-parent)|entrezgene/locuslink:116173(identity)	refseq:NP_014084.1|sgd:S000005259|dip:DIP-3026N|mint:P32453|ensemblfungi:YNL315C(gene)|ensemblfungi:YNL315C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0033615"(mitochondrial proton-transporting ATP synthase complex assembly)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR010591(ATP11)|sgd:YNL315C(identity)	-	-	crc64:61109AA4D338F2CD	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:2TJ7rZKQNb5hH5gz9i+ujOEOIOg9606	rogid:JsQu6HtKtGqAVhHzaPVc8IMYdqM559292	intact-crc:23F6304096D64CA1|rigid:bdERYZdEf3ixhCdnf5xhi5ZNSm0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32453	uniprotkb:Q969L2	intact:EBI-3306|uniprotkb:D6W0N0|ensemblfungi:YNL315C	intact:EBI-944295|uniprotkb:Q6ZMD9|uniprotkb:B2R520|ensembl:ENSP00000479708	psi-mi:atp11_yeast(display_long)|uniprotkb:ATP11(gene name)|psi-mi:ATP11(display_short)|uniprotkb:N0357(orf name)|uniprotkb:YNL315C(locus name)	psi-mi:mal2_human(display_long)|uniprotkb:MAL2(gene name)|psi-mi:MAL2(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11540714|imex:IM-24995-1933	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014084.1|sgd:S000005259|dip:DIP-3026N|mint:P32453|ensemblfungi:YNL315C(gene)|ensemblfungi:YNL315C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0033615"(mitochondrial proton-transporting ATP synthase complex assembly)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR010591(ATP11)|sgd:YNL315C(identity)	refseq:NP_443118.1|ensembl:ENSG00000147676(gene)|ensembl:ENST00000614891(transcript)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019911"(structural constituent of myelin sheath)|go:"GO:0042552"(myelination)|go:"GO:0045056"(transcytosis)|go:"GO:0045121"(membrane raft)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|interpro:IPR008253(Marvel)|interpro:IPR013295("Myelin and lymphocyte (MAL)")|interpro:IPR033240|entrezgene/locuslink:114569(identity)	-	crc64:61109AA4D338F2CD	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:JsQu6HtKtGqAVhHzaPVc8IMYdqM559292	rogid:7SApzrGTzj8V3GIwkdO0X/z6geg9606	intact-crc:1F482D0C9C14A201|rigid:QrHmWBKsB/Y8StsD9Jm3zScI0eY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32453	uniprotkb:Q8N6L0	intact:EBI-3306|uniprotkb:D6W0N0|ensemblfungi:YNL315C	intact:EBI-749265|uniprotkb:Q96MC3|ensembl:ENSP00000404220	psi-mi:atp11_yeast(display_long)|uniprotkb:ATP11(gene name)|psi-mi:ATP11(display_short)|uniprotkb:N0357(orf name)|uniprotkb:YNL315C(locus name)	psi-mi:kash5_human(display_long)|uniprotkb:KASH5(gene name)|psi-mi:KASH5(display_short)|uniprotkb:CCDC155(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 155(gene name synonym)|uniprotkb:KASH domain-containing protein 5(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11540705|imex:IM-24995-1932	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014084.1|sgd:S000005259|dip:DIP-3026N|mint:P32453|ensemblfungi:YNL315C(gene)|ensemblfungi:YNL315C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0033615"(mitochondrial proton-transporting ATP synthase complex assembly)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR010591(ATP11)|sgd:YNL315C(identity)	refseq:NP_653289.3|ensembl:ENSG00000161609(gene)|ensembl:ENST00000447857(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034397"(telomere localization)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051225"(spindle assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0090172"(microtubule cytoskeleton organization involved in homologous chromosome segregation)|go:"GO:0090220"(chromosome localization to nuclear envelope involved in homologous chromosome segregation)|go:"GO:0090619"(meiotic spindle pole)|interpro:IPR011992(EF-Hand type)|interpro:IPR028168|interpro:IPR028170|interpro:IPR039508|mint:Q8N6L0|rcsb pdb:6R2I|rcsb pdb:6WMF|entrezgene/locuslink:147872(identity)	-	crc64:61109AA4D338F2CD	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:JsQu6HtKtGqAVhHzaPVc8IMYdqM559292	rogid:Wl9L7AcvDHCZuKjYLn8QgGIbZTc9606	intact-crc:6C1024244BE7B411|rigid:pDy+f65BuJZxYqNgX8MQxtuukRk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q6RW13-2	uniprotkb:P32453	intact:EBI-11522760|ensembl:ENSP00000365816	intact:EBI-3306|uniprotkb:D6W0N0|ensemblfungi:YNL315C	psi-mi:q6rw13-2(display_long)|uniprotkb:AGTRAP(gene name)|psi-mi:AGTRAP(display_short)|uniprotkb:AT1 receptor-associated protein(gene name synonym)|uniprotkb:ATRAP(gene name synonym)	psi-mi:atp11_yeast(display_long)|uniprotkb:ATP11(gene name)|psi-mi:ATP11(display_short)|uniprotkb:N0357(orf name)|uniprotkb:YNL315C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11540696|imex:IM-24995-1931	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000177674(gene)|ensembl:ENST00000376629(transcript)|intact:EBI-741181(isoform-parent)|uniprotkb:Q6RW13-2(isoform-parent)|entrezgene/locuslink:57085(identity)	refseq:NP_014084.1|sgd:S000005259|dip:DIP-3026N|mint:P32453|ensemblfungi:YNL315C(gene)|ensemblfungi:YNL315C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0033615"(mitochondrial proton-transporting ATP synthase complex assembly)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR010591(ATP11)|sgd:YNL315C(identity)	-	-	crc64:61109AA4D338F2CD	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:PNzVis/8puQZBJ562gCqZKc078s9606	rogid:JsQu6HtKtGqAVhHzaPVc8IMYdqM559292	intact-crc:BB02F052BB2F4FE1|rigid:Gl/aNuCOn/VnsjWxu27bfTvUiH8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32458	uniprotkb:Q15019-3	intact:EBI-4178|uniprotkb:D6VWP6|ensemblfungi:YJR076C	intact:EBI-11525407|ensembl:ENSP00000385109	psi-mi:cdc11_yeast(display_long)|uniprotkb:CDC11(gene name)|psi-mi:CDC11(display_short)|uniprotkb:PSL9(gene name synonym)|uniprotkb:YJR076C(locus name)|uniprotkb:J1833(orf name)	psi-mi:q15019-3(display_long)|uniprotkb:SEPTIN2(gene name)|psi-mi:SEPTIN2(display_short)|uniprotkb:DIFF6(gene name synonym)|uniprotkb:KIAA0158(gene name synonym)|uniprotkb:NEDD5(gene name synonym)|uniprotkb:Neural precursor cell expressed developmentally down-regulated protein 5(gene name synonym)|uniprotkb:SEPT2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11540759|imex:IM-24995-1938	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012610.1|sgd:S000003837|dip:DIP-1656N|mint:P32458|ensemblfungi:YJR076C(gene)|ensemblfungi:YJR076C_mRNA(transcript)|go:"GO:0000144"(cellular bud neck septin ring)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000915"(actomyosin contractile ring assembly)|go:"GO:0000917"(division septum assembly)|go:"GO:0001400"(mating projection base)|go:"GO:0003924"(GTPase activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005619"(ascospore wall)|go:"GO:0005628"(prospore membrane)|go:"GO:0005876"(spindle microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0005935"(cellular bud neck)|go:"GO:0005940"(septin ring)|go:"GO:0010314"(phosphatidylinositol-5-phosphate binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030011"(maintenance of cell polarity)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0032160"(septin filament array)|go:"GO:0032186"(cellular bud neck septin ring organization)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042802"(identical protein binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0072687"(meiotic spindle)|go:"GO:0097271"(protein localization to bud neck)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|rcsb pdb:5AR1|sgd:YJR076C(identity)	ensembl:ENST00000401990(transcript)|ensembl:ENSG00000168385(gene)|intact:EBI-741220(isoform-parent)|uniprotkb:Q15019-3(isoform-parent)|entrezgene/locuslink:4735(identity)	-	crc64:5CFFD4CD1F6C57D4	isoform-comment:No experimental confirmation available.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:KRcNMx6EOTmvHb+6u15UrVoyb3s559292	rogid:fBY0oYn+bn7aJbJr9OyZEpqkhLc9606	intact-crc:9ED7F32A66312CAC|rigid:QIyrwTQRextVuKXuXcgYW43FQbQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P63279	uniprotkb:P32458	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	intact:EBI-4178|uniprotkb:D6VWP6|ensemblfungi:YJR076C	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:cdc11_yeast(display_long)|uniprotkb:CDC11(gene name)|psi-mi:CDC11(display_short)|uniprotkb:PSL9(gene name synonym)|uniprotkb:YJR076C(locus name)|uniprotkb:J1833(orf name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11540750|imex:IM-24995-1937	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N|entrezgene/locuslink:7329(identity)	refseq:NP_012610.1|sgd:S000003837|dip:DIP-1656N|mint:P32458|ensemblfungi:YJR076C(gene)|ensemblfungi:YJR076C_mRNA(transcript)|go:"GO:0000144"(cellular bud neck septin ring)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000915"(actomyosin contractile ring assembly)|go:"GO:0000917"(division septum assembly)|go:"GO:0001400"(mating projection base)|go:"GO:0003924"(GTPase activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005619"(ascospore wall)|go:"GO:0005628"(prospore membrane)|go:"GO:0005876"(spindle microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0005935"(cellular bud neck)|go:"GO:0005940"(septin ring)|go:"GO:0010314"(phosphatidylinositol-5-phosphate binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030011"(maintenance of cell polarity)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0032160"(septin filament array)|go:"GO:0032186"(cellular bud neck septin ring organization)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042802"(identical protein binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0072687"(meiotic spindle)|go:"GO:0097271"(protein localization to bud neck)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|rcsb pdb:5AR1|sgd:YJR076C(identity)	-	-	crc64:5CFFD4CD1F6C57D4	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	rogid:KRcNMx6EOTmvHb+6u15UrVoyb3s559292	intact-crc:74B13F6C4C9552E1|rigid:1L1ArCGXPA6CF4VZPo9nfrMSdDM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32458	uniprotkb:P23497-2	intact:EBI-4178|uniprotkb:D6VWP6|ensemblfungi:YJR076C	intact:EBI-6589365|ensembl:ENSP00000386404	psi-mi:cdc11_yeast(display_long)|uniprotkb:CDC11(gene name)|psi-mi:CDC11(display_short)|uniprotkb:PSL9(gene name synonym)|uniprotkb:YJR076C(locus name)|uniprotkb:J1833(orf name)	psi-mi:p23497-2(display_long)|uniprotkb:SP100(isoform synonym)|uniprotkb:SP100(gene name)|psi-mi:SP100(display_short)|uniprotkb:Nuclear dot-associated Sp100 protein(gene name synonym)|uniprotkb:Speckled 100 kDa(gene name synonym)|uniprotkb:SP100A(isoform synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11540741|imex:IM-24995-1936	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012610.1|sgd:S000003837|dip:DIP-1656N|mint:P32458|ensemblfungi:YJR076C(gene)|ensemblfungi:YJR076C_mRNA(transcript)|go:"GO:0000144"(cellular bud neck septin ring)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000915"(actomyosin contractile ring assembly)|go:"GO:0000917"(division septum assembly)|go:"GO:0001400"(mating projection base)|go:"GO:0003924"(GTPase activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005619"(ascospore wall)|go:"GO:0005628"(prospore membrane)|go:"GO:0005876"(spindle microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0005935"(cellular bud neck)|go:"GO:0005940"(septin ring)|go:"GO:0010314"(phosphatidylinositol-5-phosphate binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030011"(maintenance of cell polarity)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0032160"(septin filament array)|go:"GO:0032186"(cellular bud neck septin ring organization)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042802"(identical protein binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0072687"(meiotic spindle)|go:"GO:0097271"(protein localization to bud neck)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|rcsb pdb:5AR1|sgd:YJR076C(identity)	intact:EBI-751145(isoform-parent)|uniprotkb:P23497-2(isoform-parent)|ensembl:ENSG00000067066(gene)|ensembl:ENST00000409341(transcript)|entrezgene/locuslink:6672(identity)	-	crc64:5CFFD4CD1F6C57D4	isoform-comment:Major isoform.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:KRcNMx6EOTmvHb+6u15UrVoyb3s559292	rogid:HrcogLANB///4vkSYtZ7OtzOb2k9606	intact-crc:394A71A8C39E94FC|rigid:VtSDFukPmOGOWGX4zAcA3fIbVI4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32458	uniprotkb:B0QYN7	intact:EBI-4178|uniprotkb:D6VWP6|ensemblfungi:YJR076C	intact:EBI-11525376|ensembl:ENSP00000384361	psi-mi:cdc11_yeast(display_long)|uniprotkb:CDC11(gene name)|psi-mi:CDC11(display_short)|uniprotkb:PSL9(gene name synonym)|uniprotkb:YJR076C(locus name)|uniprotkb:J1833(orf name)	psi-mi:b0qyn7_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11540732|imex:IM-24995-1935	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012610.1|sgd:S000003837|dip:DIP-1656N|mint:P32458|ensemblfungi:YJR076C(gene)|ensemblfungi:YJR076C_mRNA(transcript)|go:"GO:0000144"(cellular bud neck septin ring)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000915"(actomyosin contractile ring assembly)|go:"GO:0000917"(division septum assembly)|go:"GO:0001400"(mating projection base)|go:"GO:0003924"(GTPase activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005619"(ascospore wall)|go:"GO:0005628"(prospore membrane)|go:"GO:0005876"(spindle microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0005935"(cellular bud neck)|go:"GO:0005940"(septin ring)|go:"GO:0010314"(phosphatidylinositol-5-phosphate binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030011"(maintenance of cell polarity)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0032160"(septin filament array)|go:"GO:0032186"(cellular bud neck septin ring organization)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042802"(identical protein binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0072687"(meiotic spindle)|go:"GO:0097271"(protein localization to bud neck)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|rcsb pdb:5AR1|sgd:YJR076C(identity)	refseq:XP_005255597.1|refseq:XP_005255598.1|refseq:XP_011520946.1|refseq:XP_011520947.1|ensembl:ENSG00000103275(gene)|ensembl:ENST00000402301(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0016740"(transferase activity)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|entrezgene/locuslink:7329(identity)	-	crc64:5CFFD4CD1F6C57D4	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:KRcNMx6EOTmvHb+6u15UrVoyb3s559292	rogid:zMqQOA+nnCUquTIxAUwemkElTYI9606	intact-crc:19C161EEFA062B7F|rigid:fb7aFDxlDpe3aiScIPewKqW1zHU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32463	uniprotkb:O43281-2	intact:EBI-2113|uniprotkb:D6VX08|ensemblfungi:YKL192C	intact:EBI-11525448|ensembl:ENSP00000340607	psi-mi:acpm_yeast(display_long)|uniprotkb:ACP1(gene name)|psi-mi:ACP1(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 9.6 kDa subunit(gene name synonym)|uniprotkb:YKL192C(locus name)	psi-mi:o43281-2(display_long)|uniprotkb:CASS3(gene name synonym)|uniprotkb:Cas scaffolding protein family member 3(gene name synonym)|uniprotkb:EFS(gene name)|psi-mi:EFS(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11540790|imex:IM-24995-1941	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012729.1|sgd:S000001675|dip:DIP-3990N|mint:P32463|ensemblfungi:YKL192C(gene)|ensemblfungi:YKL192C_mRNA(transcript)|go:"GO:0000035"(acyl binding)|go:"GO:0000036"(acyl carrier activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0009107"(lipoate biosynthetic process)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0070469"(respirasome)|go:"GO:0099128"(mitochondrial iron-sulfur cluster assembly complex)|interpro:IPR003231("Acyl carrier protein (ACP)")|interpro:IPR006162(Phosphopantetheine attachment site)|interpro:IPR009081(Acyl carrier protein-like)|interpro:IPR036736|reactome:R-SCE-389661|reactome:R-SCE-77289|sgd:YKL192C(identity)	intact:EBI-718488(isoform-parent)|ensembl:ENSG00000100842(gene)|ensembl:ENST00000351354(transcript)|uniprotkb:O43281-2(isoform-parent)|entrezgene/locuslink:10278(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:u1Dnj7iL+Ty5d20JWalQsAUxAS4559292	rogid:JdV6uL2+FglKvl/B+OVXk/eIIKQ9606	intact-crc:5FAE1A6979704119|rigid:FWmc9lAegRJYcR77EXv33eoE0jk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:H0YCX2	uniprotkb:P32463	intact:EBI-11525431|ensembl:ENSP00000432463	intact:EBI-2113|uniprotkb:D6VX08|ensemblfungi:YKL192C	psi-mi:h0ycx2_human(display_long)|uniprotkb:FAM193B(gene name)|psi-mi:FAM193B(display_short)	psi-mi:acpm_yeast(display_long)|uniprotkb:ACP1(gene name)|psi-mi:ACP1(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 9.6 kDa subunit(gene name synonym)|uniprotkb:YKL192C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11540779|imex:IM-24995-1940	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000146067(gene)|ensembl:ENST00000524677(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0016607"(nuclear speck)|interpro:IPR029717|interpro:IPR029722|interpro:IPR031802|entrezgene/locuslink:54540(identity)	refseq:NP_012729.1|sgd:S000001675|dip:DIP-3990N|mint:P32463|ensemblfungi:YKL192C(gene)|ensemblfungi:YKL192C_mRNA(transcript)|go:"GO:0000035"(acyl binding)|go:"GO:0000036"(acyl carrier activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0009107"(lipoate biosynthetic process)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0070469"(respirasome)|go:"GO:0099128"(mitochondrial iron-sulfur cluster assembly complex)|interpro:IPR003231("Acyl carrier protein (ACP)")|interpro:IPR006162(Phosphopantetheine attachment site)|interpro:IPR009081(Acyl carrier protein-like)|interpro:IPR036736|reactome:R-SCE-389661|reactome:R-SCE-77289|sgd:YKL192C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:aMr6uO1ZOLPg/THCfO6xLJWkO7Y9606	rogid:u1Dnj7iL+Ty5d20JWalQsAUxAS4559292	intact-crc:738522A5A0067591|rigid:re4U2XvrEj12Jkyq5nuQJkV7lmM	false	sufficient binding region:61-508	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9Y2J4	uniprotkb:P32458	intact:EBI-746752|intact:EBI-28986657|ensembl:ENSP00000409999|uniprotkb:Q53EP1|uniprotkb:Q96F99|uniprotkb:Q9UKB4|uniprotkb:A8K6F1|uniprotkb:B7Z5Q1|uniprotkb:E9PHW3	intact:EBI-4178|uniprotkb:D6VWP6|ensemblfungi:YJR076C	psi-mi:amol2_human(display_long)|uniprotkb:Leman coiled-coil protein(gene name synonym)|uniprotkb:AMOTL2(gene name)|psi-mi:AMOTL2(display_short)|uniprotkb:KIAA0989(gene name synonym)	psi-mi:cdc11_yeast(display_long)|uniprotkb:CDC11(gene name)|psi-mi:CDC11(display_short)|uniprotkb:PSL9(gene name synonym)|uniprotkb:YJR076C(locus name)|uniprotkb:J1833(orf name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11540768|imex:IM-24995-1939	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001265612.1|refseq:NP_001265614.1|ensembl:ENSG00000114019(gene)|refseq:XP_006713717.1|refseq:NP_057285.3|refseq:XP_011511183.1|ensembl:ENST00000422605(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0003365"(establishment of cell polarity involved in ameboidal cell migration)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0035329"(hippo signaling)|go:"GO:0055037"(recycling endosome)|interpro:IPR009114(Angiomotin)|interpro:IPR024646|mint:Q9Y2J4|reactome:R-HSA-2028269|refseq:XP_016862069.1|refseq:XP_016862070.1|refseq:XP_016862071.1|ensembl:ENST00000249883|ensembl:ENSP00000249883|ensembl:ENSP00000409999|ensembl:ENST00000513145|ensembl:ENSP00000425475|ensembl:ENST00000514516|ensembl:ENSP00000424765|dip:DIP-57510N|entrezgene/locuslink:51421(identity)	refseq:NP_012610.1|sgd:S000003837|dip:DIP-1656N|mint:P32458|ensemblfungi:YJR076C(gene)|ensemblfungi:YJR076C_mRNA(transcript)|go:"GO:0000144"(cellular bud neck septin ring)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000915"(actomyosin contractile ring assembly)|go:"GO:0000917"(division septum assembly)|go:"GO:0001400"(mating projection base)|go:"GO:0003924"(GTPase activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005619"(ascospore wall)|go:"GO:0005628"(prospore membrane)|go:"GO:0005876"(spindle microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0005935"(cellular bud neck)|go:"GO:0005940"(septin ring)|go:"GO:0010314"(phosphatidylinositol-5-phosphate binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030011"(maintenance of cell polarity)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0032160"(septin filament array)|go:"GO:0032186"(cellular bud neck septin ring organization)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042802"(identical protein binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0072687"(meiotic spindle)|go:"GO:0097271"(protein localization to bud neck)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|rcsb pdb:5AR1|sgd:YJR076C(identity)	-	-	crc64:5CFFD4CD1F6C57D4	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:SHtKAcLLnTpSSLwVE7yQ1WECoZk9606	rogid:KRcNMx6EOTmvHb+6u15UrVoyb3s559292	intact-crc:90DBEC7B42C7010C|rigid:jvPfSTR3KoFtSOGZW0zusIT43Pw	false	sufficient binding region:314-779	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q86WT6-2	uniprotkb:P32464	intact:EBI-11525489|ensembl:ENSP00000342922|ensembl:ENSP00000479720	intact:EBI-8859|ensemblfungi:YKL189W|uniprotkb:D6VX11	psi-mi:q86wt6-2(display_long)|uniprotkb:RING-type E3 ubiquitin transferase TRIM69(gene name synonym)|uniprotkb:TRIM69(gene name)|psi-mi:TRIM69(display_short)|uniprotkb:RFP-like domain-containing protein trimless(gene name synonym)|uniprotkb:RING finger protein 36(gene name synonym)|uniprotkb:RNF36(gene name synonym)|uniprotkb:Tripartite motif-containing protein 69(gene name synonym)|uniprotkb:HSD-34(orf name)|uniprotkb:HSD34(orf name)	psi-mi:hym1_yeast(display_long)|uniprotkb:YKL189W(locus name)|uniprotkb:HYM1(gene name)|psi-mi:HYM1(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11540829|imex:IM-24995-1945	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-749955(isoform-parent)|uniprotkb:Q86WT6-2(isoform-parent)|ensembl:ENSG00000185880(gene)|ensembl:ENSG00000278211(gene)|ensembl:ENST00000338264(transcript)|ensembl:ENST00000618398(transcript)|entrezgene/locuslink:140691(identity)	ensemblfungi:YKL189W(gene)|ensemblfungi:YKL189W_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0000920"(septum digestion after cytokinesis)|go:"GO:0005933"(cellular bud)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007118"(budding cell apical bud growth)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043332"(mating projection tip)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0044732"(mitotic spindle pole body)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013878(Mo25-like)|interpro:IPR016024(Armadillo-type fold)|reactome:R-SCE-6798695|refseq:NP_012732.1|sgd:S000001672|mint:P32464|dip:DIP-5425N|sgd:YKL189W(identity)	-	-	crc64:F48860754C892BA9	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:J0mzn4PSX5vWZqt4X3Ee1Wxx5hw9606	rogid:pOlQFFuYgFzmqf3ZGUVkBj9h7Uc559292	intact-crc:FA0368E17697B48E|rigid:iy9StxYBZ2cOGdyRWb1zM+gLOQA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P14373	uniprotkb:P32464	intact:EBI-719493|uniprotkb:A2BE15|uniprotkb:Q5RJA8|uniprotkb:Q5ST26|uniprotkb:Q6LA73|uniprotkb:Q6NXR9|uniprotkb:Q9BZY6|uniprotkb:Q9UJL3|ensembl:ENSP00000383555|ensembl:ENSP00000392787|ensembl:ENSP00000405229|ensembl:ENSP00000414793|ensembl:ENSP00000366404	intact:EBI-8859|ensemblfungi:YKL189W|uniprotkb:D6VX11	psi-mi:tri27_human(display_long)|uniprotkb:TRIM27(gene name)|psi-mi:TRIM27(display_short)|uniprotkb:RNF76(gene name synonym)|uniprotkb:RFP(gene name synonym)|uniprotkb:Ret finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 27(gene name synonym)|uniprotkb:RING finger protein 76(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM27(gene name synonym)	psi-mi:hym1_yeast(display_long)|uniprotkb:YKL189W(locus name)|uniprotkb:HYM1(gene name)|psi-mi:HYM1(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11540820|imex:IM-24995-1944	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006501.1|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0090281"(negative regulation of calcium ion import)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR020457|interpro:IPR035791|interpro:IPR043136|mint:P14373|reactome:R-HSA-3232142|reactome:R-HSA-9635465|reactome:R-HSA-8948751|ensembl:ENSG00000204713(gene)|ensembl:ENSG00000215641(gene)|ensembl:ENSG00000229006(gene)|ensembl:ENSG00000234495(gene)|ensembl:ENSG00000237071(gene)|ensembl:ENST00000377199(transcript)|ensembl:ENST00000400720(transcript)|ensembl:ENST00000431123(transcript)|ensembl:ENST00000435528(transcript)|ensembl:ENST00000437160(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001650"(fibrillar center)|go:"GO:0002820"(negative regulation of adaptive immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|entrezgene/locuslink:5987(identity)	ensemblfungi:YKL189W(gene)|ensemblfungi:YKL189W_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0000920"(septum digestion after cytokinesis)|go:"GO:0005933"(cellular bud)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007118"(budding cell apical bud growth)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043332"(mating projection tip)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0044732"(mitotic spindle pole body)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013878(Mo25-like)|interpro:IPR016024(Armadillo-type fold)|reactome:R-SCE-6798695|refseq:NP_012732.1|sgd:S000001672|mint:P32464|dip:DIP-5425N|sgd:YKL189W(identity)	-	-	crc64:F48860754C892BA9	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:dsfH5OUghD8KSaTz1SFw9OYVTK49606	rogid:pOlQFFuYgFzmqf3ZGUVkBj9h7Uc559292	intact-crc:2607752F65A9562F|rigid:2igrLlIUhR+ddAP5LUqSOBOq6IE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O14879	uniprotkb:P32464	intact:EBI-745127|uniprotkb:Q99634|uniprotkb:Q9BSK7|ensembl:ENSP00000360876|ensembl:ENSP00000360883|ensembl:ENSP00000505987	intact:EBI-8859|ensemblfungi:YKL189W|uniprotkb:D6VX11	psi-mi:ifit3_human(display_long)|uniprotkb:ISG-60(gene name synonym)|uniprotkb:CIG49(gene name synonym)|uniprotkb:Retinoic acid-induced gene G protein(gene name synonym)|uniprotkb:Interferon-induced protein with tetratricopeptide repeats 4(gene name synonym)|uniprotkb:Interferon-induced 60 kDa protein(gene name synonym)|uniprotkb:IFIT3(gene name)|psi-mi:IFIT3(display_short)|uniprotkb:IFI60(gene name synonym)|uniprotkb:IFIT4(gene name synonym)|uniprotkb:CIG-49(gene name synonym)|uniprotkb:ISG60(gene name synonym)	psi-mi:hym1_yeast(display_long)|uniprotkb:YKL189W(locus name)|uniprotkb:HYM1(gene name)|psi-mi:HYM1(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11540810|imex:IM-24995-1943	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001026853.1|refseq:NP_001540.2|ensembl:ENSG00000119917(gene)|ensembl:ENST00000371811(transcript)|ensembl:ENST00000371818(transcript)|ensembl:ENST00000679781(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009615"(response to virus)|go:"GO:0035457"(cellular response to interferon-alpha)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR024122|mint:O14879|rcsb pdb:6C6K|reactome:R-HSA-909733|dip:DIP-37890N|entrezgene/locuslink:3437(identity)	ensemblfungi:YKL189W(gene)|ensemblfungi:YKL189W_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0000920"(septum digestion after cytokinesis)|go:"GO:0005933"(cellular bud)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007118"(budding cell apical bud growth)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043332"(mating projection tip)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0044732"(mitotic spindle pole body)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013878(Mo25-like)|interpro:IPR016024(Armadillo-type fold)|reactome:R-SCE-6798695|refseq:NP_012732.1|sgd:S000001672|mint:P32464|dip:DIP-5425N|sgd:YKL189W(identity)	-	-	crc64:F48860754C892BA9	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:K8uDHfKNx0YBgTkwpEaRKvx24/k9606	rogid:pOlQFFuYgFzmqf3ZGUVkBj9h7Uc559292	intact-crc:C66CDFCC9D0E03B0|rigid:1oLkIlyzqwp89jwljG2iTwKN9ww	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32464	uniprotkb:Q08379	intact:EBI-8859|ensemblfungi:YKL189W|uniprotkb:D6VX11	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	psi-mi:hym1_yeast(display_long)|uniprotkb:YKL189W(locus name)|uniprotkb:HYM1(gene name)|psi-mi:HYM1(display_short)	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11540799|imex:IM-24995-1942	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YKL189W(gene)|ensemblfungi:YKL189W_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0000920"(septum digestion after cytokinesis)|go:"GO:0005933"(cellular bud)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007118"(budding cell apical bud growth)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043332"(mating projection tip)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0044732"(mitotic spindle pole body)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013878(Mo25-like)|interpro:IPR016024(Armadillo-type fold)|reactome:R-SCE-6798695|refseq:NP_012732.1|sgd:S000001672|mint:P32464|dip:DIP-5425N|sgd:YKL189W(identity)	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N|entrezgene/locuslink:2801(identity)	-	crc64:F48860754C892BA9	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2017/05/26	rogid:pOlQFFuYgFzmqf3ZGUVkBj9h7Uc559292	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	intact-crc:32E7FB2407FDC2FE|rigid:TQTCCQDUSkfgGVImrqXaG4EjE+c	false	-	sufficient binding region:383-1002	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32464	uniprotkb:Q9BYV6-2	intact:EBI-8859|ensemblfungi:YKL189W|uniprotkb:D6VX11	intact:EBI-11522718|ensembl:ENSP00000297348	psi-mi:hym1_yeast(display_long)|uniprotkb:YKL189W(locus name)|uniprotkb:HYM1(gene name)|psi-mi:HYM1(display_short)	psi-mi:q9byv6-2(display_long)|uniprotkb:TRIM55(gene name)|psi-mi:TRIM55(display_short)|uniprotkb:MURF2(gene name synonym)|uniprotkb:Muscle-specific RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 29(gene name synonym)|uniprotkb:RNF29(gene name synonym)|uniprotkb:p50(isoform synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11540865|imex:IM-24995-1949	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YKL189W(gene)|ensemblfungi:YKL189W_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0000920"(septum digestion after cytokinesis)|go:"GO:0005933"(cellular bud)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007118"(budding cell apical bud growth)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043332"(mating projection tip)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0044732"(mitotic spindle pole body)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013878(Mo25-like)|interpro:IPR016024(Armadillo-type fold)|reactome:R-SCE-6798695|refseq:NP_012732.1|sgd:S000001672|mint:P32464|dip:DIP-5425N|sgd:YKL189W(identity)	intact:EBI-2341179(isoform-parent)|uniprotkb:Q9BYV6-2(isoform-parent)|ensembl:ENSG00000147573(gene)|ensembl:ENST00000353317(transcript)|entrezgene/locuslink:84675(identity)	-	crc64:F48860754C892BA9	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:pOlQFFuYgFzmqf3ZGUVkBj9h7Uc559292	rogid:9t8UhK+Z1yBqjnQrOqPD76NuXGg9606	intact-crc:33E681716AB16962|rigid:Q00+a0cI06mHJvICa9lINScSzyk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9BRK4	uniprotkb:P32464	intact:EBI-741037|ensembl:ENSP00000359240|ensembl:ENSP00000359243|uniprotkb:Q8N3I0|uniprotkb:Q96J79|uniprotkb:Q96JL2|uniprotkb:B1AL14|uniprotkb:D3DR72	intact:EBI-8859|ensemblfungi:YKL189W|uniprotkb:D6VX11	psi-mi:lzts2_human(display_long)|uniprotkb:Protein LAPSER1(gene name synonym)|uniprotkb:LZTS2(gene name)|psi-mi:LZTS2(display_short)|uniprotkb:KIAA1813(gene name synonym)|uniprotkb:LAPSER1(gene name synonym)	psi-mi:hym1_yeast(display_long)|uniprotkb:YKL189W(locus name)|uniprotkb:HYM1(gene name)|psi-mi:HYM1(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11540856|imex:IM-24995-1948	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_115805.1|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030496"(midbody)|go:"GO:0031982"(vesicle)|go:"GO:0051013"(microtubule severing)|go:"GO:0051168"(nuclear export)|go:"GO:0051255"(spindle midzone assembly)|go:"GO:0060682"(primary ureteric bud growth)|go:"GO:0072197"(ureter morphogenesis)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|interpro:IPR028597|mint:Q9BRK4|ensembl:ENSG00000107816(gene)|ensembl:ENST00000370220(transcript)|ensembl:ENST00000370223(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0008285"(negative regulation of cell population proliferation)|refseq:XP_016872269.1|refseq:NP_001305028.1|refseq:NP_001305029.1|refseq:NP_001305030.1|refseq:XP_005270279.1|entrezgene/locuslink:84445(identity)	ensemblfungi:YKL189W(gene)|ensemblfungi:YKL189W_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0000920"(septum digestion after cytokinesis)|go:"GO:0005933"(cellular bud)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007118"(budding cell apical bud growth)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043332"(mating projection tip)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0044732"(mitotic spindle pole body)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013878(Mo25-like)|interpro:IPR016024(Armadillo-type fold)|reactome:R-SCE-6798695|refseq:NP_012732.1|sgd:S000001672|mint:P32464|dip:DIP-5425N|sgd:YKL189W(identity)	-	-	crc64:F48860754C892BA9	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:OaMJmnmfm6JniKUJeyg7fS6zRcw9606	rogid:pOlQFFuYgFzmqf3ZGUVkBj9h7Uc559292	intact-crc:3D1B27EE97AAB6A4|rigid:mGzOaKzCbGqGbkKZDZDgf+WUa10	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32464	uniprotkb:Q8NA61-2	intact:EBI-8859|ensemblfungi:YKL189W|uniprotkb:D6VX11	intact:EBI-11524851|ensembl:ENSP00000368249|ensembl:ENSP00000480148	psi-mi:hym1_yeast(display_long)|uniprotkb:YKL189W(locus name)|uniprotkb:HYM1(gene name)|psi-mi:HYM1(display_short)	psi-mi:q8na61-2(display_long)|uniprotkb:CBY2(gene name)|psi-mi:CBY2(display_short)|uniprotkb:SPERT(gene name synonym)|uniprotkb:Spermatid-associated protein(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11540847|imex:IM-24995-1947	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YKL189W(gene)|ensemblfungi:YKL189W_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0000920"(septum digestion after cytokinesis)|go:"GO:0005933"(cellular bud)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007118"(budding cell apical bud growth)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043332"(mating projection tip)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0044732"(mitotic spindle pole body)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013878(Mo25-like)|interpro:IPR016024(Armadillo-type fold)|reactome:R-SCE-6798695|refseq:NP_012732.1|sgd:S000001672|mint:P32464|dip:DIP-5425N|sgd:YKL189W(identity)	intact:EBI-741724(isoform-parent)|ensembl:ENSG00000174015(gene)|ensembl:ENST00000378966(transcript)|ensembl:ENST00000610924(transcript)|uniprotkb:Q8NA61-2(isoform-parent)|entrezgene/locuslink:220082(identity)	-	crc64:F48860754C892BA9	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:pOlQFFuYgFzmqf3ZGUVkBj9h7Uc559292	rogid:SogYcXGGMYRYzB9xKC5o0pEtsDs9606	intact-crc:5E8DE84D82AA4143|rigid:C9ytOIqS0AwNc/ow8UyMDpknYcQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32464	uniprotkb:Q8N3J3-3	intact:EBI-8859|ensemblfungi:YKL189W|uniprotkb:D6VX11	intact:EBI-11061081|ensembl:ENSP00000245382	psi-mi:hym1_yeast(display_long)|uniprotkb:YKL189W(locus name)|uniprotkb:HYM1(gene name)|psi-mi:HYM1(display_short)	psi-mi:q8n3j3-3(display_long)|uniprotkb:HROB(gene name)|psi-mi:HROB(display_short)|uniprotkb:C17orf53(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11540838|imex:IM-24995-1946	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YKL189W(gene)|ensemblfungi:YKL189W_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0000920"(septum digestion after cytokinesis)|go:"GO:0005933"(cellular bud)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007118"(budding cell apical bud growth)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043332"(mating projection tip)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0044732"(mitotic spindle pole body)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013878(Mo25-like)|interpro:IPR016024(Armadillo-type fold)|reactome:R-SCE-6798695|refseq:NP_012732.1|sgd:S000001672|mint:P32464|dip:DIP-5425N|sgd:YKL189W(identity)	intact:EBI-8465499(isoform-parent)|uniprotkb:Q8N3J3-3(isoform-parent)|ensembl:ENSG00000125319(gene)|ensembl:ENST00000245382(transcript)|entrezgene/locuslink:78995(identity)	-	crc64:F48860754C892BA9	isoform-comment:No experimental confirmation available.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:pOlQFFuYgFzmqf3ZGUVkBj9h7Uc559292	rogid:CV8rVs1P1HH0w/igNSebho0bupA9606	intact-crc:9BD1D2AF5CE3210E|rigid:4axyQ/CKyNEmBlfsCq5Oe22Q6PE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8N5R6	uniprotkb:P32502	intact:EBI-740841|intact:EBI-953781|uniprotkb:B3KQ49|uniprotkb:A8K3U4|uniprotkb:A8MPQ6|uniprotkb:A8MV61|uniprotkb:A8MVU9|uniprotkb:Q9H5Q6|uniprotkb:Q8TAX6|intact:EBI-2320546|intact:EBI-11522976	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:ccd33_human(display_long)|uniprotkb:CCDC33(gene name)|psi-mi:CCDC33(display_short)|uniprotkb:Cancer/testis antigen 61(gene name synonym)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11540902|imex:IM-24995-1953	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_079331.3|interpro:IPR000008(C2 calcium-dependent membrane targeting)|go:"GO:0005777"(peroxisome)|refseq:NP_001274110.1|refseq:NP_877592.2|mint:Q8N5R6|interpro:IPR035892|interpro:IPR039889|entrezgene/locuslink:80125(identity)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	-	-	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2021/11/30	rogid:eEIn7pQyfdHWx8TeLJpYy0i/gww9606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:8AD50279D61610E0|rigid:5jyzF2xloZxY9H2TFqrNqEYTXQA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P26641	uniprotkb:P32497	intact:EBI-351467|uniprotkb:Q6PJ62|uniprotkb:Q6PK31|uniprotkb:Q96CU2|uniprotkb:Q9P196|intact:EBI-2321928|uniprotkb:B4DTG2|ensembl:ENSP00000331901	intact:EBI-8965|ensemblfungi:YMR309C|uniprotkb:D6W0D6	psi-mi:ef1g_human(display_long)|uniprotkb:PRO1608(orf name)|uniprotkb:EEF1G(gene name)|psi-mi:EEF1G(display_short)|uniprotkb:EF1G(gene name synonym)|uniprotkb:eEF-1B gamma(gene name synonym)	psi-mi:eif3c_yeast(display_long)|uniprotkb:NIP1(gene name)|psi-mi:NIP1(display_short)|uniprotkb:YMR309C(locus name)|uniprotkb:YM9924.01C(orf name)|uniprotkb:YM9952.11C(orf name)|uniprotkb:Eukaryotic translation initiation factor 3 93 kDa subunit(gene name synonym)|uniprotkb:Nuclear transport protein NIP1(gene name synonym)|uniprotkb:Translation initiation factor eIF3, p93 subunit(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11540893|imex:IM-24995-1952	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001395.1|ensembl:ENSG00000254772(gene)|ensembl:ENST00000329251(transcript)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006414"(translational elongation)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001662(Translation elongation factor EF1B, gamma chain, conserved)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR036249|interpro:IPR036282|interpro:IPR036433|interpro:IPR040079|mint:P26641|rcsb pdb:1PBU|rcsb pdb:5DQS|rcsb pdb:5JPO|reactome:R-HSA-156842|dip:DIP-32516N|entrezgene/locuslink:1937(identity)	go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|ensemblfungi:YMR309C(gene)|ensemblfungi:YMR309C_mRNA(transcript)|go:"GO:0006413"(translational initiation)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0043614"(multi-eIF complex)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR008905(Eukaryotic translation initiation factor 3 subunit 8, N-terminal)|interpro:IPR027516|rcsb pdb:3JAP|rcsb pdb:4U1C|rcsb pdb:5H7U|rcsb pdb:6FYX|rcsb pdb:6FYY|rcsb pdb:6GSM|rcsb pdb:6GSN|rcsb pdb:6ZCE|rcsb pdb:6ZU9|reactome:R-SCE-156827|reactome:R-SCE-72649|reactome:R-SCE-72695|reactome:R-SCE-72702|refseq:NP_014040.1|sgd:S000004926|mint:P32497|dip:DIP-1470N|sgd:YMR309C(identity)	-	-	crc64:EE05097C44C45A4C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:biVN96umeEdPm/wvPN4VwbSRHTs9606	rogid:D2B5DHNCbowAIRjWdoxAkeP/CXk559292	intact-crc:3E970FEE21E57622|rigid:UDC3Tvp+dHT39OFxJPk6nv7LHOc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q86UW9	uniprotkb:P32477	intact:EBI-740376|uniprotkb:Q96H69|uniprotkb:Q9H890|uniprotkb:Q9P200|uniprotkb:Q6XM88|ensembl:ENSP00000322885|ensembl:ENSP00000390218|ensembl:ENSP00000411986|uniprotkb:Q6XM87|intact:EBI-10192429|uniprotkb:Q4ZH49	intact:EBI-7910|uniprotkb:D6VW83|ensemblfungi:YJL101C	psi-mi:dtx2_human(display_long)|uniprotkb:RING finger protein 58(gene name synonym)|uniprotkb:DTX2(gene name)|psi-mi:DTX2(display_short)|uniprotkb:KIAA1528(gene name synonym)|uniprotkb:RNF58(gene name synonym)|uniprotkb:Protein deltex-2(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase DTX2(gene name synonym)	psi-mi:gsh1_yeast(display_long)|uniprotkb:GSH1(gene name)|psi-mi:GSH1(display_short)|uniprotkb:YJL101C(locus name)|uniprotkb:J0832(orf name)|uniprotkb:Gamma-glutamylcysteine synthetase(gene name synonym)|uniprotkb:Gamma-ECS(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11540883|imex:IM-24995-1951	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001096064.1|refseq:NP_001096065.1|refseq:NP_001096066.1|refseq:NP_065943.2|ensembl:ENSP00000322885|ensembl:ENSP00000390218|ensembl:ENSP00000411986|ensembl:ENST00000446820|ensembl:ENSP00000392545|ensembl:ENSG00000091073(gene)|ensembl:ENST00000324432(transcript)|ensembl:ENST00000413936(transcript)|ensembl:ENST00000430490(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031965"(nuclear membrane)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR004170(WWE)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR018123|interpro:IPR018957|interpro:IPR037197|interpro:IPR039396|interpro:IPR039398|interpro:IPR039399|mint:Q86UW9|rcsb pdb:6IR0|rcsb pdb:6Y22|rcsb pdb:6Y2X|rcsb pdb:6Y3J|reactome:R-HSA-2122948|refseq:XP_011514074.1|refseq:XP_011514075.1|refseq:XP_011514076.1|refseq:XP_011514077.1|refseq:XP_005250188.1|refseq:XP_005250189.1|refseq:XP_016867212.1|refseq:XP_016867213.1|refseq:XP_016867214.1|refseq:XP_016867215.1|refseq:XP_016867216.1|entrezgene/locuslink:113878(identity)	refseq:NP_012434.1|sgd:S000003637|interpro:IPR004308(Glutamate-cysteine ligase catalytic subunit)|rcsb pdb:3IG5|rcsb pdb:3IG8|rcsb pdb:3LVV|rcsb pdb:3LVW|interpro:IPR014746(Glutamine synthetase/guanido kinase, catalytic region)|ensemblfungi:YJL101C(gene)|ensemblfungi:YJL101C_mRNA(transcript)|go:"GO:0004357"(glutamate-cysteine ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006750"(glutathione biosynthetic process)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0046686"(response to cadmium ion)|sgd:YJL101C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:ugnjqAbG6Ekyc8MGugCnjc9zVaI9606	rogid:83EkWwY4UUf7Rvoxtj6HiUr/uHE559292	intact-crc:ADA798D4EE300448|rigid:Tf2s0BnZ1YD0Jp6k+Nk+tDfHNzM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9P286	uniprotkb:P32474	intact:EBI-741896|ensembl:ENSP00000322957|ensembl:ENSP00000367679|ensembl:ENSP00000367686|intact:EBI-1051061|uniprotkb:A8K5T6|uniprotkb:D3DW14|uniprotkb:Q5W115|uniprotkb:Q8TB93|uniprotkb:Q9BX09|uniprotkb:Q9ULF6	intact:EBI-2343998|uniprotkb:D6VTD9|uniprotkb:E9P901|ensemblfungi:YDR518W	psi-mi:pak5_human(display_long)|uniprotkb:PAK5(gene name)|psi-mi:PAK5(display_short)|uniprotkb:KIAA1264(gene name synonym)|uniprotkb:PAK7(gene name synonym)|uniprotkb:p21-activated kinase 5(gene name synonym)|uniprotkb:p21-activated kinase 7(gene name synonym)	psi-mi:eug1_yeast(display_long)|uniprotkb:EUG1(gene name)|psi-mi:EUG1(display_short)|uniprotkb:Endoplasmic reticulum protein EUG1(gene name synonym)|uniprotkb:D9719.23(orf name)|uniprotkb:YDR518W(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11540874|imex:IM-24995-1950	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000101349(gene)|go:"GO:0045202"(synapse)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR028754|interpro:IPR033923|interpro:IPR036936|rcsb pdb:2F57|reactome:R-HSA-428540|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013405|reactome:R-HSA-9013407|go:"GO:0043408"(regulation of MAPK cascade)|ensembl:ENST00000353224(transcript)|ensembl:ENST00000378423(transcript)|ensembl:ENST00000378429(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007165"(signal transduction)|go:"GO:0007612"(learning)|go:"GO:0007613"(memory)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016477"(cell migration)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0035556"(intracellular signal transduction)|refseq:NP_065074.1|refseq:NP_817127.1|refseq:XP_016883449.1|refseq:XP_016883450.1|refseq:XP_016883451.1|refseq:XP_016883452.1|refseq:XP_016883453.1|refseq:XP_016883454.1|entrezgene/locuslink:57144(identity)	refseq:NP_010806.1|sgd:S000002926|interpro:IPR005792(Protein disulphide isomerase)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR036249|ensemblfungi:YDR518W(gene)|ensemblfungi:YDR518W_mRNA(transcript)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006457"(protein folding)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0019153"("protein-disulfide reductase (glutathione) activity")|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0051082"(unfolded protein binding)|sgd:YDR518W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2017/06/28	rogid:xxNDwmHn4jv8toBmviGjFwBU32E9606	rogid:HGjMgN6bwOoRQeGJ4/p/rM1ay1g559292	intact-crc:0BD70457F1C8FC68|rigid:5tzMT9/FZi944PcoXr1XnJ9v9mA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32502	uniprotkb:A0A0R4J2E4	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	intact:EBI-11525602|ensembl:ENSP00000324292	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:a0a0r4j2e4_human(display_long)|uniprotkb:FBF1(gene name)|psi-mi:FBF1(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11540929|imex:IM-24995-1956	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	ensembl:ENSG00000188878(gene)|ensembl:ENST00000319129(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0060271"(cilium assembly)|go:"GO:0090162"(establishment of epithelial cell polarity)|go:"GO:0097539"(ciliary transition fiber)|interpro:IPR033561|entrezgene/locuslink:85302(identity)	-	crc64:A5409FAF1594854C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/03/16	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	rogid:N4h8foiP1+HSYZRE7i66zhtqKlQ9606	intact-crc:65D3004C212138D1|rigid:o1ADKMU+Hf56w0Mn/5d6v5jxhCA	false	-	sufficient binding region:649-1092	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32502	uniprotkb:A0A0C4DFM0	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	intact:EBI-11525587|ensembl:ENSP00000216465	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:a0a0c4dfm0_human(display_long)|uniprotkb:hCG_22265(orf name)|uniprotkb:GSTZ1(gene name)|psi-mi:GSTZ1(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11540920|imex:IM-24995-1955	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	refseq:NP_665877.1|ensembl:ENSG00000100577(gene)|ensembl:ENST00000216465(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0006559"(L-phenylalanine catabolic process)|go:"GO:0006572"(tyrosine catabolic process)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0016034"(maleylacetoacetate isomerase activity)|go:"GO:0016740"(transferase activity)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR005955(Maleylacetoacetate isomerase)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR034330|interpro:IPR034333|interpro:IPR036249|interpro:IPR036282|interpro:IPR040079|entrezgene/locuslink:2954(identity)	-	crc64:A5409FAF1594854C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	rogid:kAk3W6wTlhMKasX8CzDxF6U5/jc9606	intact-crc:8D54DA510C2F9AF5|rigid:8sFEQIVUuAUQLaGakM51sY13Xcs	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32502	intact:EBI-11525577	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	-	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:pde4dip(display_short)|psi-mi:EBI-11525577(display_long)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11540911|imex:IM-24995-1954	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	entrezgene/locuslink:9659(identity)	-	crc64:A5409FAF1594854C	no-uniprot-update:	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	rogid:1FG5rtwoLqpyiNu81cqSpFdaXDY9606	intact-crc:244EC06F71ABF568|rigid:3PkRr2VqTLqLOCdfIfBqDQ8Hk2E	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32502	uniprotkb:Q7Z6G3-2	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	intact:EBI-10172876|ensembl:ENSP00000457354|intact:EBI-14062040	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:q7z6g3-2(display_long)|uniprotkb:EFCBP2(gene name synonym)|uniprotkb:Neuronal calcium-binding protein 2(gene name synonym)|uniprotkb:Synaptotagmin-interacting protein 2(gene name synonym)|uniprotkb:NECAB2(gene name)|psi-mi:NECAB2(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11540951|imex:IM-24995-1958	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	ensembl:ENSG00000103154(gene)|ensembl:ENST00000565691(transcript)|uniprotkb:Q7Z6G3-2(isoform-parent)|intact:EBI-950070(isoform-parent)|entrezgene/locuslink:54550(identity)	-	crc64:A5409FAF1594854C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	rogid:4S7oIx6h+mKzV3EPxqcfMNqaNko9606	intact-crc:CBEBE3EB4960145D|rigid:83Cnms/xtYhuLT9dx6N+G4rH+m0	false	-	sufficient binding region:65-303	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32502	uniprotkb:G5E962	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	intact:EBI-11525615|ensembl:ENSP00000328177	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:g5e962_human(display_long)|uniprotkb:hCG_1644200(orf name)|uniprotkb:MAGEA11(gene name)|psi-mi:MAGEA11(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11540940|imex:IM-24995-1957	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	refseq:NP_001011544.1|ensembl:ENSG00000185247(gene)|ensembl:ENST00000333104(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016604"(nuclear body)|interpro:IPR002190(MAGE protein)|interpro:IPR021072|interpro:IPR030099|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|entrezgene/locuslink:4110(identity)	-	crc64:A5409FAF1594854C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	rogid:sVB0aA6yibWUx/d2SE+pwpKKgtI9606	intact-crc:481C547626F5D4B6|rigid:6aq7Xa/T42Sl2M+Fq5wpd1aNTio	false	-	sufficient binding region:82-400	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32502	uniprotkb:O15156-2	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	intact:EBI-11522250|ensembl:ENSP00000406286	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:o15156-2(display_long)|uniprotkb:ZBTB7B(gene name)|psi-mi:ZBTB7B(display_short)|uniprotkb:Krueppel-related zinc finger protein cKrox(gene name synonym)|uniprotkb:T-helper-inducing POZ/Krueppel-like factor(gene name synonym)|uniprotkb:ZBTB15(gene name synonym)|uniprotkb:ZFP67(gene name synonym)|uniprotkb:ZNF857B(gene name synonym)|uniprotkb:Zinc finger and BTB domain-containing protein 15(gene name synonym)|uniprotkb:Zinc finger protein 67 homolog(gene name synonym)|uniprotkb:Zinc finger protein 857B(gene name synonym)|uniprotkb:Zinc finger protein Th-POK(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11540989|imex:IM-24995-1962	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	intact:EBI-740434(isoform-parent)|ensembl:ENSG00000160685(gene)|ensembl:ENST00000417934(transcript)|uniprotkb:O15156-2(isoform-parent)|entrezgene/locuslink:51043(identity)	-	crc64:A5409FAF1594854C	isoform-comment:No experimental confirmation available.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	rogid:41NEFYyprTXI+fOHVFh78TPKF289606	intact-crc:76C58780673A2E3B|rigid:/+UmWdQzSLdY3ig1erzXeqIHwFY	false	-	sufficient binding region:35-573	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32502	uniprotkb:O14964	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	intact:EBI-740220|uniprotkb:Q9NR36|ensembl:ENSP00000331201|ensembl:ENSP00000504106	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:hgs_human(display_long)|uniprotkb:Protein pp110(gene name synonym)|uniprotkb:Hrs(gene name synonym)|uniprotkb:HGS(gene name)|psi-mi:HGS(display_short)|uniprotkb:HRS(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11540980|imex:IM-24995-1961	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	refseq:NP_004703.1|dip:DIP-29050N|ensembl:ENSG00000185359(gene)|ensembl:ENST00000329138(transcript)|ensembl:ENST00000676546(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0007165"(signal transduction)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010324"(membrane invagination)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010642"(negative regulation of platelet-derived growth factor receptor signaling pathway)|go:"GO:0016197"(endosomal transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032585"(multivesicular body membrane)|go:"GO:0033565"(ESCRT-0 complex)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043405"(regulation of MAP kinase activity)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072657"(protein localization to membrane)|go:"GO:0097013"(phagocytic vesicle lumen)|go:"GO:1903543"(positive regulation of exosomal secretion)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR002014(VHS)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017073(Ubiquitin binding protein, Hrs/VPS27)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR024641|mint:O14964|rcsb pdb:2D3G|rcsb pdb:3F1I|rcsb pdb:3OBQ|rcsb pdb:3ZYQ|rcsb pdb:4AVX|reactome:R-HSA-182971|reactome:R-HSA-432720|reactome:R-HSA-5689880|reactome:R-HSA-6807004|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8875360|reactome:R-HSA-9013420|reactome:R-HSA-917729|reactome:R-HSA-9635644|reactome:R-HSA-9636383|reactome:R-HSA-9706019|entrezgene/locuslink:9146(identity)	-	crc64:A5409FAF1594854C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	rogid:z/AnREuqEpyJ9/Zj6JFCJCJem1I9606	intact-crc:693092F406F1515E|rigid:i5XcpStCfjaiDLc3pfO7yC2tQhI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O14641	uniprotkb:P32502	intact:EBI-740850|ensembl:ENSP00000005340|uniprotkb:Q53XM0|uniprotkb:D3DTN3	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:dvl2_human(display_long)|uniprotkb:DSH homolog 2(gene name synonym)|uniprotkb:DVL2(gene name)|psi-mi:DVL2(display_short)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11540971|imex:IM-24995-1960	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004413.1|ensembl:ENSG00000004975(gene)|ensembl:ENST00000005340(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005109"(frizzled binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0007507"(heart development)|go:"GO:0016235"(aggresome)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044340"(canonical Wnt signaling pathway involved in regulation of cell proliferation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0150012"(positive regulation of neuron projection arborization)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008341(Dishevelled-2 region)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:O14641|rcsb pdb:2REY|rcsb pdb:3CBX|rcsb pdb:3CBY|rcsb pdb:3CBZ|rcsb pdb:3CC0|rcsb pdb:4WIP|rcsb pdb:5LNP|rcsb pdb:5SUY|rcsb pdb:5SUZ|rcsb pdb:6IW3|rcsb pdb:6JCK|reactome:R-HSA-201681|reactome:R-HSA-201688|reactome:R-HSA-2028269|reactome:R-HSA-4086400|reactome:R-HSA-4608870|reactome:R-HSA-4641258|reactome:R-HSA-4641262|reactome:R-HSA-5099900|reactome:R-HSA-5368598|reactome:R-HSA-5663220|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9673324|ensembl:ENSP00000005340|dip:DIP-34433N|entrezgene/locuslink:1856(identity)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	-	-	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:2Vdc8oRnT4Mz/j+EXQXrL3AszOc9606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:BD01EDCEF79DF03E|rigid:pm9EJtyO2bHhLP88C1nUq0TAN68	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:I6L8A6	uniprotkb:P32502	intact:EBI-11525639|ensembl:ENSP00000354024	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:i6l8a6_human(display_long)|uniprotkb:DNA endonuclease RBBP8(gene name synonym)|uniprotkb:RBBP8(gene name)|psi-mi:RBBP8(display_short)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11540962|imex:IM-24995-1959	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000101773(gene)|ensembl:ENST00000360790(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003677"(DNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0010792"(DNA double-strand break processing involved in repair via single-strand annealing)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|interpro:IPR013882(DNA repair protein Sae2)|interpro:IPR019518|interpro:IPR033316|interpro:IPR033594|entrezgene/locuslink:5932(identity)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	-	-	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:GHiZbuwZR+0GRaqg0vt6Dsg4pCk9606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:60BE05B5BE2C096D|rigid:9aDIyPR3htM3T7hxoOi2T6lRyt0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32502	uniprotkb:O60232	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	intact:EBI-741415|ensembl:ENSP00000312318	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:znrd2_human(display_long)|uniprotkb:ZNRD2(gene name)|psi-mi:ZNRD2(display_short)|uniprotkb:Autoantigen p27(gene name synonym)|uniprotkb:SSSCA1(gene name synonym)|uniprotkb:Sjoegren syndrome/scleroderma autoantigen 1(gene name synonym)|uniprotkb:Zinc ribbon domain-containing protein 2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11541027|imex:IM-24995-1966	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	refseq:NP_006387.1|ensembl:ENSG00000173465(gene)|ensembl:ENST00000309328(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0051301"(cell division)|interpro:IPR009563(Sjogrens syndrome scleroderma autoantigen 1)|rcsb pdb:6HCZ|entrezgene/locuslink:10534(identity)	-	crc64:A5409FAF1594854C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	rogid:Uou80pZneoL39/0YYzb1TAbiB2I9606	intact-crc:F572CE437B29C4D8|rigid:Mv4bbKj+10EcTY9SVZ16eZ7Fty4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32502	uniprotkb:O43809	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	intact:EBI-355720|uniprotkb:Q6IB85|uniprotkb:Q6NE84|ensembl:ENSP00000300291	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:cpsf5_human(display_long)|uniprotkb:NUDT21(gene name)|psi-mi:NUDT21(display_short)|uniprotkb:CFIM25(gene name synonym)|uniprotkb:CPSF25(gene name synonym)|uniprotkb:CPSF5(gene name synonym)|uniprotkb:Cleavage and polyadenylation specificity factor 25 kDa subunit(gene name synonym)|uniprotkb:Nucleoside diphosphate-linked moiety X motif 21(gene name synonym)|uniprotkb:Cleavage factor Im complex 25 kDa subunit(gene name synonym)|uniprotkb:Nudix hydrolase 21(gene name synonym)|uniprotkb:Pre-mRNA cleavage factor Im 68 kDa subunit(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11541018|imex:IM-24995-1965	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	refseq:NP_008937.1|ensembl:ENSG00000167005(gene)|ensembl:ENST00000300291(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0005849"(mRNA cleavage factor complex)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0006397"(mRNA processing)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0031439"(positive regulation of mRNA cleavage)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0042382"(paraspeckles)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051290"(protein heterotetramerization)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|go:"GO:0110104"(mRNA alternative polyadenylation)|go:"GO:1900365"(positive regulation of mRNA polyadenylation)|go:"GO:1990120"(messenger ribonucleoprotein complex assembly)|go:"GO:2000738"(positive regulation of stem cell differentiation)|go:"GO:2000975"(positive regulation of pro-B cell differentiation)|interpro:IPR000086(NUDIX hydrolase, core)|interpro:IPR015797(NUDIX)|interpro:IPR016706(Cleavage and polyadenylation specificity factor, 25 kDa subunit)|mint:O43809|rcsb pdb:2CL3|rcsb pdb:2J8Q|rcsb pdb:3BAP|rcsb pdb:3BHO|rcsb pdb:3MDG|rcsb pdb:3MDI|rcsb pdb:3N9U|rcsb pdb:3P5T|rcsb pdb:3P6Y|rcsb pdb:3Q2S|rcsb pdb:3Q2T|rcsb pdb:5R4P|rcsb pdb:5R4Q|rcsb pdb:5R4R|rcsb pdb:5R4S|rcsb pdb:5R4T|rcsb pdb:5R4U|rcsb pdb:5R64|rcsb pdb:5R65|rcsb pdb:5R66|rcsb pdb:5R67|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-77595|dip:DIP-42502N|entrezgene/locuslink:11051(identity)	-	crc64:A5409FAF1594854C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	rogid:Acad4mYVuS+Eox+X2CH8PYUkGAA9606	intact-crc:229F3CF70A5D64C9|rigid:BP13JVI+4PVMBrwgCeg4x1bZzTw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O43597	uniprotkb:P32502	intact:EBI-742487|uniprotkb:Q5T6Z7|ensembl:ENSP00000366306|ensembl:ENSP00000366308|uniprotkb:B2R9J9	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:spy2_human(display_long)|uniprotkb:SPRY2(gene name)|psi-mi:SPRY2(display_short)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11541009|imex:IM-24995-1964	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005833.1|rcsb pdb:5HL0|reactome:R-HSA-1295596|reactome:R-HSA-182971|rcsb pdb:5HKZ|ensembl:ENST00000377102(transcript)|ensembl:ENST00000377104(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|ensembl:ENSG00000136158(gene)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030291"(protein serine/threonine kinase inhibitor activity)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031345"(negative regulation of cell projection organization)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0032587"(ruffle membrane)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0045165"(cell fate commitment)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048513"(animal organ development)|go:"GO:0051387"(negative regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060437"(lung growth)|go:"GO:0060449"(bud elongation involved in lung branching)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:1900747"(negative regulation of vascular endothelial growth factor signaling pathway)|go:"GO:1902747"(negative regulation of lens fiber cell differentiation)|go:"GO:1990752"(microtubule end)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR007875(Sprouty)|interpro:IPR030780|mint:O43597|rcsb pdb:3BUM|rcsb pdb:3OB1|rcsb pdb:5HKY|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|refseq:NP_001305465.1|refseq:NP_001305466.1|refseq:NP_001305467.1|entrezgene/locuslink:10253(identity)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	-	-	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:u1omauzisc6MdZlogMotUmtauSI9606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:E5E46A4EFDA52079|rigid:3mEi232CWxAHeNyuaGfgfCcKtHw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O15217	uniprotkb:P32502	intact:EBI-752440|uniprotkb:Q5T7Q8|uniprotkb:Q9BX18|uniprotkb:Q9H414|uniprotkb:B2RD15|uniprotkb:Q6P4G1|ensembl:ENSP00000359998|ensembl:ENSP00000360002	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:gsta4_human(display_long)|uniprotkb:Glutathione S-transferase A4-4(gene name synonym)|uniprotkb:GST class-alpha member 4(gene name synonym)|uniprotkb:GSTA4(gene name)|psi-mi:GSTA4(display_short)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11541000|imex:IM-24995-1963	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001503.1|refseq:XP_005249092.1|ensembl:ENSG00000170899(gene)|ensembl:ENST00000370959(transcript)|ensembl:ENST00000370963(transcript)|go:"GO:0004364"(glutathione transferase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0006805"(xenobiotic metabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|interpro:IPR003080(Glutathione S-transferase, alpha class)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR036249|interpro:IPR036282|interpro:IPR040079|rcsb pdb:1GUL|rcsb pdb:1GUM|rcsb pdb:3IK7|reactome:R-HSA-156590|entrezgene/locuslink:2941(identity)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	-	-	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:9yVcqmJL64S0kxOW5RJWbOJ25bo9606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:F0842C2787A0EC50|rigid:vivFJzLRywr+nlr9ldQiyJabTCY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O95273	uniprotkb:P32502	intact:EBI-748961|uniprotkb:A8K3Q0|uniprotkb:A8K3U2|uniprotkb:Q6ZQN9|uniprotkb:Q7Z519|uniprotkb:Q8NBS7|uniprotkb:Q8NBY2|uniprotkb:Q9NS19|uniprotkb:Q9NYH3|uniprotkb:Q9UHX9|ensembl:ENSP00000300213	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:ccdb1_human(display_long)|uniprotkb:Grap2 and cyclin-D-interacting protein(gene name synonym)|uniprotkb:Human homolog of Maid(gene name synonym)|uniprotkb:CCNDBP1(gene name)|psi-mi:CCNDBP1(display_short)|uniprotkb:DIP1(gene name synonym)|uniprotkb:GCIP(gene name synonym)|uniprotkb:HHM(gene name synonym)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11541063|imex:IM-24995-1970	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_036274.3|ensembl:ENSG00000166946(gene)|ensembl:ENST00000300213(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0016604"(nuclear body)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR026907|mint:O95273|rcsb pdb:3AY5|entrezgene/locuslink:23582(identity)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	-	-	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Vi9aoFc+Mov6P3X6KGmsTxXqxvM9606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:C69ED317ADFD5B8E|rigid:aQNC2q2a67Rxblovfqfkg6WAZLM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O95197-3	uniprotkb:P32502	intact:EBI-11525735|ensembl:ENSP00000440874	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:o95197-3(display_long)|uniprotkb:RTN3(gene name)|psi-mi:RTN3(display_short)|uniprotkb:ASYIP(gene name synonym)|uniprotkb:Homolog of ASY protein(gene name synonym)|uniprotkb:NSPL2(gene name synonym)|uniprotkb:Neuroendocrine-specific protein-like 2(gene name synonym)|uniprotkb:Neuroendocrine-specific protein-like II(gene name synonym)|uniprotkb:A1(isoform synonym)|uniprotkb:B1(isoform synonym)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11541054|imex:IM-24995-1969	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000133318(gene)|ensembl:ENST00000537981(transcript)|intact:EBI-740467(isoform-parent)|uniprotkb:O95197-3(isoform-parent)|entrezgene/locuslink:10313(identity)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	-	-	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:+TJnANu85CM52dRZ6s+hYMlUABE9606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:C63389F6A28120FA|rigid:qZKS34xaUps9By4csjsNmwDjfLQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O76083-2	uniprotkb:P32502	intact:EBI-11524542|ensembl:ENSP00000335242	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:o76083-2(display_long)|uniprotkb:PDE9A(gene name)|psi-mi:PDE9A(display_short)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11541045|imex:IM-24995-1968	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-742764(isoform-parent)|ensembl:ENSG00000160191(gene)|ensembl:ENST00000335512(transcript)|uniprotkb:O76083-2(isoform-parent)|entrezgene/locuslink:5152(identity)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	-	-	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:nTzgeYGOwTM/7VJUgxSnlnDiCFo9606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:720A225646461F76|rigid:K4ak8/bIDA6IYLzdcaWwFmmTfPg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32502	uniprotkb:O75506	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	intact:EBI-748664|uniprotkb:Q7Z5Z3|uniprotkb:Q53XA8|ensembl:ENSP00000392896|ensembl:ENSP00000458007	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:hsbp1_human(display_long)|uniprotkb:Nasopharyngeal carcinoma-associated antigen 13(gene name synonym)|uniprotkb:HSBP1(gene name)|psi-mi:HSBP1(display_short)|uniprotkb:HSF1BP(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11541036|imex:IM-24995-1967	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	refseq:NP_001528.1|interpro:IPR009643(Heat shock factor binding 1)|rcsb pdb:3CI9|reactome:R-HSA-3371511|reactome:R-HSA-3371568|reactome:R-HSA-3371571|ensembl:ENSG00000230989(gene)|ensembl:ENST00000433866(transcript)|ensembl:ENST00000570259(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006936"(muscle contraction)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0070370"(cellular heat acclimation)|entrezgene/locuslink:3281(identity)	-	crc64:A5409FAF1594854C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	rogid:3JML7OxHIw8M91ARKPfOhJ9kVbk9606	intact-crc:F6AE036B11665833|rigid:dyaEbB+dUfXqlZ1ueee42GVMNUY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32502	uniprotkb:P07910-2	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	intact:EBI-5280084|ensembl:ENSP00000442816|ensembl:ENSP00000450544|ensembl:ENSP00000450725|ensembl:ENSP00000451176	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:p07910-2(display_long)|uniprotkb:HNRNPC(gene name)|psi-mi:HNRNPC(display_short)|uniprotkb:HNRPC(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11541099|imex:IM-24995-1974	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	uniprotkb:P07910-2(isoform-parent)|intact:EBI-357966(isoform-parent)|ensembl:ENSG00000092199(gene)|ensembl:ENST00000430246(transcript)|ensembl:ENST00000553300(transcript)|ensembl:ENST00000554969(transcript)|ensembl:ENST00000556897(transcript)|entrezgene/locuslink:3183(identity)	-	crc64:A5409FAF1594854C	isoform-comment:Contains a phosphoserine at position 107. Contains a phosphoserine at position 108.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	rogid:r7AhGozE3aHdynLr8DrXPRtOuyI9606	intact-crc:99BE5D5569B1C2AB|rigid:1cqi50rFIN9YGgs3/g3Rad18Oyk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P04271	uniprotkb:P32502	intact:EBI-458391|ensembl:ENSP00000291700|ensembl:ENSP00000380769|uniprotkb:D3DSN6	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:s100b_human(display_long)|uniprotkb:S100B(gene name)|psi-mi:S100B(display_short)|uniprotkb:S100 calcium-binding protein B(gene name synonym)|uniprotkb:S-100 protein subunit beta(gene name synonym)|uniprotkb:S-100 protein beta chain(gene name synonym)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11541090|imex:IM-24995-1973	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000160307(gene)|ensembl:ENST00000291700(transcript)|ensembl:ENST00000397648(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007409"(axonogenesis)|go:"GO:0007417"(central nervous system development)|go:"GO:0007611"(learning or memory)|go:"GO:0007613"(memory)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0031643"(positive regulation of myelination)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044548"(S100 protein binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0048168"(regulation of neuronal synaptic plasticity)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048708"(astrocyte differentiation)|go:"GO:0050786"(RAGE receptor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0051597"(response to methylmercury)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:2001015"(negative regulation of skeletal muscle cell differentiation)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR018247|interpro:IPR028481|mint:P04271|rcsb pdb:1MQ1|rcsb pdb:1UWO|rcsb pdb:2H61|rcsb pdb:2M49|rcsb pdb:2PRU|rcsb pdb:3CZT|rcsb pdb:3D0Y|rcsb pdb:3D10|rcsb pdb:3HCM|rcsb pdb:4XYN|rcsb pdb:5CSF|rcsb pdb:5CSI|rcsb pdb:5CSJ|rcsb pdb:5CSN|rcsb pdb:5D7F|go:"GO:0051384"(response to glucocorticoid)|reactome:R-HSA-1251985|reactome:R-HSA-445989|reactome:R-HSA-879415|reactome:R-HSA-933542|refseq:NP_006263.1|refseq:XP_016883913.1|entrezgene/locuslink:6285(identity)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	-	-	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:e6p9zHV5sa8+lIZgYW1aiAAfq3s9606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:3AE088934348195A|rigid:R0s2qnF0R4cHOZOdmXpPr9Eil5U	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P00492	uniprotkb:P32502	intact:EBI-748210|uniprotkb:A6NHF0|uniprotkb:B2R8M9|ensembl:ENSP00000298556	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:hprt_human(display_long)|uniprotkb:HPRT1(gene name)|psi-mi:HPRT1(display_short)|uniprotkb:HPRT(gene name synonym)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11541081|imex:IM-24995-1972	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000185.1|ensembl:ENSG00000165704(gene)|ensembl:ENST00000298556(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001913"(T cell mediated cytotoxicity)|go:"GO:0001975"(response to amphetamine)|go:"GO:0004422"(hypoxanthine phosphoribosyltransferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006164"(purine nucleotide biosynthetic process)|go:"GO:0006166"(purine ribonucleoside salvage)|go:"GO:0006168"(adenine salvage)|go:"GO:0006178"(guanine salvage)|go:"GO:0007625"(grooming behavior)|go:"GO:0007626"(locomotory behavior)|go:"GO:0021756"(striatum development)|go:"GO:0021895"(cerebral cortex neuron differentiation)|go:"GO:0021954"(central nervous system neuron development)|go:"GO:0032263"(GMP salvage)|go:"GO:0032264"(IMP salvage)|go:"GO:0042417"(dopamine metabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043103"(hypoxanthine salvage)|go:"GO:0045964"(positive regulation of dopamine metabolic process)|go:"GO:0046038"(GMP catabolic process)|go:"GO:0046040"(IMP metabolic process)|go:"GO:0046100"(hypoxanthine metabolic process)|go:"GO:0046651"(lymphocyte proliferation)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0052657"(guanine phosphoribosyltransferase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000836(Phosphoribosyltransferase)|interpro:IPR005904(Hypoxanthine phosphoribosyl transferase)|interpro:IPR029057|mint:P00492|rcsb pdb:1BZY|rcsb pdb:1D6N|rcsb pdb:1HMP|rcsb pdb:1Z7G|go:"GO:0048813"(dendrite morphogenesis)|rcsb pdb:2VFA|rcsb pdb:3GEP|rcsb pdb:3GGC|rcsb pdb:3GGJ|rcsb pdb:4IJQ|rcsb pdb:4KN6|rcsb pdb:4RAB|rcsb pdb:4RAC|rcsb pdb:4RAD|rcsb pdb:4RAN|rcsb pdb:4RAO|rcsb pdb:4RAQ|rcsb pdb:5BRN|rcsb pdb:5BSK|rcsb pdb:5HIA|rcsb pdb:5W8V|rcsb pdb:6BNJ|reactome:R-HSA-74217|entrezgene/locuslink:3251(identity)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	-	-	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:w87Sv/qOAkHFqJm0vu0Ayqlz7TA9606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:37BDF7509E372209|rigid:PISP8RuaU+d5E5vA27VfIBZftkI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O96006	uniprotkb:P32502	intact:EBI-740037|uniprotkb:Q96BY4|ensembl:ENSP00000370616|ensembl:ENSP00000370620|ensembl:ENSP00000370621|ensembl:ENSP00000498725	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:zbed1_human(display_long)|uniprotkb:ZBED1(gene name)|psi-mi:ZBED1(display_short)|uniprotkb:ALTE(gene name synonym)|uniprotkb:DREF(gene name synonym)|uniprotkb:KIAA0785(gene name synonym)|uniprotkb:TRAMP(gene name synonym)|uniprotkb:dREF homolog(gene name synonym)|uniprotkb:Putative Ac-like transposable element(gene name synonym)|uniprotkb:DNA replication-related element-binding factor(gene name synonym)|uniprotkb:Zinc finger BED domain-containing protein 1(gene name synonym)|uniprotkb:hDREF(gene name synonym)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11541072|imex:IM-24995-1971	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164606.1|refseq:NP_001164607.1|refseq:NP_004720.1|ensembl:ENSG00000214717(gene)|ensembl:ENST00000381218(transcript)|ensembl:ENST00000381222(transcript)|ensembl:ENST00000381223(transcript)|ensembl:ENST00000652001(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0031965"(nuclear membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044828"(negative regulation by host of viral genome replication)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0061665"(SUMO ligase activity)|go:"GO:1990466"(protein autosumoylation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003656(Zinc finger, BED-type predicted)|interpro:IPR008906(HAT dimerisation)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR036236|mint:O96006|rcsb pdb:2CT5|reactome:R-HSA-4551638|go:"GO:0005813"(centrosome)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016605"(PML body)|entrezgene/locuslink:9189(identity)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	-	-	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:jl97ZV2Kz5YAmQKktWt/wk7OkRw9606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:B2B913B9ABF0341E|rigid:xnjMmbDtA3wd0wWMkdA+FSzpBpo	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P15531	uniprotkb:P32502	intact:EBI-741141|ensembl:ENSP00000376892|uniprotkb:Q6FGK3|uniprotkb:Q86XQ2|uniprotkb:Q9UDJ6	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:ndka_human(display_long)|uniprotkb:Tumor metastatic process-associated protein(gene name synonym)|uniprotkb:Metastasis inhibition factor nm23(gene name synonym)|uniprotkb:Granzyme A-activated DNase(gene name synonym)|uniprotkb:NME1(gene name)|psi-mi:NME1(display_short)|uniprotkb:NDPKA(gene name synonym)|uniprotkb:NM23(gene name synonym)|uniprotkb:NM23-H1(gene name synonym)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11541135|imex:IM-24995-1978	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000260.1|refseq:NP_937818.1|ensembl:ENSG00000239672(gene)|ensembl:ENST00000393196(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0002762"(negative regulation of myeloid leukocyte differentiation)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004536"(deoxyribonuclease activity)|go:"GO:0004550"(nucleoside diphosphate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0006183"(GTP biosynthetic process)|go:"GO:0006228"(UTP biosynthetic process)|go:"GO:0006241"(CTP biosynthetic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007595"(lactation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014075"(response to amine)|go:"GO:0016020"(membrane)|go:"GO:0019215"(intermediate filament binding)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051591"(response to cAMP)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071398"(cellular response to fatty acid)|interpro:IPR001564(Nucleoside diphosphate kinase, core)|go:"GO:0019899"(enzyme binding)|interpro:IPR023005|go:"GO:0021766"(hippocampus development)|interpro:IPR034907|interpro:IPR036850|mint:P15531|go:"GO:0030154"(cell differentiation)|go:"GO:0032587"(ruffle membrane)|rcsb pdb:1JXV|rcsb pdb:1UCN|go:"GO:0033574"(response to testosterone)|go:"GO:0035690"|rcsb pdb:2HVD|rcsb pdb:2HVE|rcsb pdb:3L7U|rcsb pdb:4ENO|rcsb pdb:5UI4|reactome:R-HSA-499943|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043024"(ribosomal small subunit binding)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|dip:DIP-39164N|entrezgene/locuslink:4830(identity)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	-	-	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Ut4gK1Xq786CaZzvqdS1eiU5op89606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:DF816DECEA86DB1B|rigid:ApbTyx03y8NP4HEFMg5O/XwkyP8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32502	uniprotkb:P14373	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	intact:EBI-719493|uniprotkb:A2BE15|uniprotkb:Q5RJA8|uniprotkb:Q5ST26|uniprotkb:Q6LA73|uniprotkb:Q6NXR9|uniprotkb:Q9BZY6|uniprotkb:Q9UJL3|ensembl:ENSP00000383555|ensembl:ENSP00000392787|ensembl:ENSP00000405229|ensembl:ENSP00000414793|ensembl:ENSP00000366404	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:tri27_human(display_long)|uniprotkb:TRIM27(gene name)|psi-mi:TRIM27(display_short)|uniprotkb:RNF76(gene name synonym)|uniprotkb:RFP(gene name synonym)|uniprotkb:Ret finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 27(gene name synonym)|uniprotkb:RING finger protein 76(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM27(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11541126|imex:IM-24995-1977	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	refseq:NP_006501.1|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0090281"(negative regulation of calcium ion import)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR020457|interpro:IPR035791|interpro:IPR043136|mint:P14373|reactome:R-HSA-3232142|reactome:R-HSA-9635465|reactome:R-HSA-8948751|ensembl:ENSG00000204713(gene)|ensembl:ENSG00000215641(gene)|ensembl:ENSG00000229006(gene)|ensembl:ENSG00000234495(gene)|ensembl:ENSG00000237071(gene)|ensembl:ENST00000377199(transcript)|ensembl:ENST00000400720(transcript)|ensembl:ENST00000431123(transcript)|ensembl:ENST00000435528(transcript)|ensembl:ENST00000437160(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001650"(fibrillar center)|go:"GO:0002820"(negative regulation of adaptive immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|entrezgene/locuslink:5987(identity)	-	crc64:A5409FAF1594854C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	rogid:dsfH5OUghD8KSaTz1SFw9OYVTK49606	intact-crc:41C8DDFE94214F10|rigid:8TmBF4FZuoTGdTF2GdyM2n5jne4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P14174	uniprotkb:P32502	intact:EBI-372712|uniprotkb:A5Z1R8|uniprotkb:B2R4S3|uniprotkb:Q6FHV0|uniprotkb:Q2V4Y5|ensembl:ENSP00000215754|ensembl:ENSP00000482779	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:mif_human(display_long)|uniprotkb:MIF(gene name)|psi-mi:MIF(display_short)|uniprotkb:MMIF(gene name synonym)|uniprotkb:GLIF(gene name synonym)|uniprotkb:Phenylpyruvate tautomerase(gene name synonym)|uniprotkb:Glycosylation-inhibiting factor(gene name synonym)|uniprotkb:L-dopachrome tautomerase(gene name synonym)|uniprotkb:L-dopachrome isomerase(gene name synonym)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11541117|imex:IM-24995-1976	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002406.1|ensembl:ENST00000215754(transcript)|ensembl:ENST00000613839(transcript)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0004167"(dopachrome isomerase activity)|go:"GO:0005125"(cytokine activity)|go:"GO:0005126"(cytokine receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|ensembl:ENSG00000276701(gene)|go:"GO:0006954"(inflammatory response)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0009986"(cell surface)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010739"(positive regulation of protein kinase A signaling)|go:"GO:0010760"(negative regulation of macrophage chemotaxis)|go:"GO:0019752"(carboxylic acid metabolic process)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031982"(vesicle)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042056"(chemoattractant activity)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043030"(regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|ensembl:ENSG00000240972(gene)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045087"(innate immune response)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0050178"(phenylpyruvate tautomerase activity)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070207"(protein homotrimerization)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0090344"(negative regulation of cell aging)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR001398(Macrophage migration inhibitory factor)|interpro:IPR014347(Tautomerase)|interpro:IPR019829|mint:P14174|rcsb pdb:1CGQ|rcsb pdb:1GCZ|rcsb pdb:1GD0|rcsb pdb:1GIF|rcsb pdb:1LJT|rcsb pdb:1MIF|rcsb pdb:1P1G|rcsb pdb:2OOH|rcsb pdb:2OOW|rcsb pdb:2OOZ|rcsb pdb:3B9S|rcsb pdb:3CE4|rcsb pdb:3DJH|rcsb pdb:3DJI|rcsb pdb:3HOF|rcsb pdb:3IJG|rcsb pdb:3IJJ|rcsb pdb:3JSF|rcsb pdb:3JSG|rcsb pdb:3JTU|rcsb pdb:3L5P|rcsb pdb:3L5R|rcsb pdb:3L5S|rcsb pdb:3L5T|rcsb pdb:3L5U|rcsb pdb:3L5V|rcsb pdb:3SMB|rcsb pdb:3SMC|rcsb pdb:3U18|rcsb pdb:3WNR|rcsb pdb:3WNS|rcsb pdb:3WNT|rcsb pdb:4ETG|rcsb pdb:4EUI|rcsb pdb:4EVG|rcsb pdb:4F2K|rcsb pdb:4GRN|rcsb pdb:4GRO|rcsb pdb:4GRP|rcsb pdb:4GRQ|rcsb pdb:4GRR|rcsb pdb:4GRU|rcsb pdb:4GUM|rcsb pdb:4K9G|rcsb pdb:4OSF|rcsb pdb:4OYQ|rcsb pdb:4P01|rcsb pdb:4P0H|rcsb pdb:4PKK|rcsb pdb:4PKZ|rcsb pdb:4PLU|rcsb pdb:4TRF|rcsb pdb:4TRU|rcsb pdb:4WR8|rcsb pdb:4WRB|rcsb pdb:4XX7|rcsb pdb:4XX8|rcsb pdb:4Z15|rcsb pdb:4Z1T|rcsb pdb:4Z1U|rcsb pdb:5B4O|rcsb pdb:5BS9|rcsb pdb:5BSC|rcsb pdb:5BSI|rcsb pdb:5BSJ|rcsb pdb:5EIZ|rcsb pdb:5HVS|rcsb pdb:5HVT|rcsb pdb:5HVV|rcsb pdb:5J7P|rcsb pdb:5J7Q|rcsb pdb:5UMJ|rcsb pdb:5UMK|rcsb pdb:5UZY|rcsb pdb:5V70|rcsb pdb:5V73|rcsb pdb:5XEJ|rcsb pdb:1CA7|rcsb pdb:6B1C|rcsb pdb:6B1K|rcsb pdb:6B2C|rcsb pdb:6BG6|rcsb pdb:6BG7|rcsb pdb:6CB5|rcsb pdb:6CBF|rcsb pdb:6CBG|rcsb pdb:6FVE|rcsb pdb:6FVH|rcsb pdb:6OY8|rcsb pdb:6OYB|rcsb pdb:6OYE|rcsb pdb:6OYG|rcsb pdb:6PEG|reactome:R-HSA-202733|reactome:R-HSA-6798695|reactome:R-HSA-8950505|rcsb pdb:6CBH|dip:DIP-31137N|entrezgene/locuslink:4282(identity)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	-	-	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Vk+Sfaz5c59y8dKKJ4Qn+7fjwvQ9606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:70CA2083113C2B35|rigid:e777KalAyYVYYod1TcXejrZ/0h0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P08727	uniprotkb:P32502	intact:EBI-742756|uniprotkb:Q5XG83|uniprotkb:Q6NW33|uniprotkb:Q7L5M9|uniprotkb:Q96A53|uniprotkb:Q96FV1|uniprotkb:Q9BYF9|uniprotkb:Q9P1Y4|uniprotkb:B2R874|ensembl:ENSP00000355124	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:k1c19_human(display_long)|uniprotkb:Cytokeratin-19(gene name synonym)|uniprotkb:Keratin-19(gene name synonym)|uniprotkb:KRT19(gene name)|psi-mi:KRT19(display_short)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11541108|imex:IM-24995-1975	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002267.2|ensembl:ENSG00000171345(gene)|ensembl:ENST00000361566(transcript)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0030018"(Z disc)|go:"GO:0042383"(sarcolemma)|go:"GO:0043034"(costamere)|go:"GO:0043627"(response to estrogen)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0060706"(cell differentiation involved in embryonic placenta development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071944"(cell periphery)|go:"GO:1990357"(terminal web)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR039008|mint:P08727|reactome:R-HSA-6805567|reactome:R-HSA-6809371|dip:DIP-35655N|entrezgene/locuslink:3880(identity)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	-	-	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:fqsG2nghpcmTtI39LiYVLNYuFIA9606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:41519504A04953BD|rigid:GRI60gRVRUUKPM4dUxsitr4Uytg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32502	uniprotkb:P19012	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	intact:EBI-739566|uniprotkb:Q53XV8|uniprotkb:Q9BUG4|uniprotkb:B3KQY1|uniprotkb:B3KRA2|uniprotkb:E0CX14|ensembl:ENSP00000254043|ensembl:ENSP00000377546	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:k1c15_human(display_long)|uniprotkb:KRT15(gene name)|psi-mi:KRT15(display_short)|uniprotkb:KRTB(gene name synonym)|uniprotkb:Cytokeratin-15(gene name synonym)|uniprotkb:Keratin-15(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11541144|imex:IM-24995-1979	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	refseq:NP_002266.2|ensembl:ENSG00000171346(gene)|ensembl:ENST00000254043(transcript)|ensembl:ENST00000393976(transcript)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0008544"(epidermis development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097110"(scaffold protein binding)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR039008|mint:P19012|reactome:R-HSA-6805567|reactome:R-HSA-6809371|entrezgene/locuslink:3866(identity)	-	crc64:A5409FAF1594854C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	rogid:WrZQBYQvrWcfrR5ojWXrXp6spPE9606	intact-crc:69BD16A38F0CE8FF|rigid:0gvENk/O19qCoFW25bO+8k1LDdA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38432	uniprotkb:P32502	intact:EBI-945751|uniprotkb:B2R931|ensembl:ENSP00000240316	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:coil_human(display_long)|uniprotkb:COIL(gene name)|psi-mi:COIL(display_short)|uniprotkb:CLN80(gene name synonym)|uniprotkb:p80-coilin(gene name synonym)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11541172|imex:IM-24995-1982	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004636.1|dip:DIP-38503N|ensembl:ENSG00000121058(gene)|ensembl:ENST00000240316(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0015030"(Cajal body)|go:"GO:0016020"(membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0030619"(U1 snRNA binding)|go:"GO:0030620"(U2 snRNA binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR024822|interpro:IPR031722|mint:P38432|entrezgene/locuslink:8161(identity)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	-	-	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:hd5p6AbyA/GYNEeca99Mdb41qM09606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:A0D4EDE1897FFCEA|rigid:xh14u3vqTThWSaUBxfd/0lTwQwA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P35520	uniprotkb:P32502	intact:EBI-740135|uniprotkb:Q99425|uniprotkb:Q9BWC5|uniprotkb:B2R993|uniprotkb:D3DSK4|intact:EBI-14245939|ensembl:ENSP00000344460|ensembl:ENSP00000352643|ensembl:ENSP00000381225|ensembl:ENSP00000381231	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:cbs_human(display_long)|uniprotkb:CBS(gene name)|psi-mi:CBS(display_short)|uniprotkb:Serine sulfhydrase(gene name synonym)|uniprotkb:Beta-thionase(gene name synonym)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11541162|imex:IM-24995-1981	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000062.1|refseq:NP_001171479.1|refseq:NP_001171480.1|ensembl:ENSG00000160200(gene)|ensembl:ENST00000352178(transcript)|ensembl:ENST00000359624(transcript)|ensembl:ENST00000398158(transcript)|go:"GO:0004122"(cystathionine beta-synthase activity)|ensembl:ENST00000398165(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006535"(cysteine biosynthetic process from serine)|go:"GO:0006563"(L-serine metabolic process)|go:"GO:0006565"(L-serine catabolic process)|go:"GO:0019343"(cysteine biosynthetic process via cystathionine)|go:"GO:0019344"(cysteine biosynthetic process)|go:"GO:0019346"(transsulfuration)|go:"GO:0019448"(L-cysteine catabolic process)|go:"GO:0019825"(oxygen binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0020037"(heme binding)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042262"(DNA protection)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043418"(homocysteine catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0050421"("nitrite reductase (NO-forming) activity")|go:"GO:0050667"(homocysteine metabolic process)|go:"GO:0070025"(carbon monoxide binding)|go:"GO:0070026"(nitric oxide binding)|go:"GO:0070814"(hydrogen sulfide biosynthetic process)|go:"GO:0072341"(modified amino acid binding)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR001216(Cysteine synthase/cystathionine beta-synthase P-phosphate-binding site)|interpro:IPR001926(Pyridoxal phosphate-dependent enzyme, beta subunit)|interpro:IPR005857(Cystathionine beta-synthase)|interpro:IPR036052|mint:P35520|rcsb pdb:1JBQ|rcsb pdb:1M54|rcsb pdb:4COO|rcsb pdb:4L0D|rcsb pdb:4L27|rcsb pdb:4L28|rcsb pdb:4L3V|rcsb pdb:4PCU|rcsb pdb:4UUU|rcsb pdb:5MMS|reactome:R-HSA-1614603|reactome:R-HSA-2408508|refseq:XP_011528079.1|refseq:XP_011528083.1|refseq:XP_011528084.1|refseq:XP_011544396.1|refseq:XP_011544397.1|refseq:XP_011544399.1|refseq:XP_011544400.1|refseq:XP_011544401.1|refseq:NP_001307227.1|refseq:NP_001308002.1|refseq:XP_016883700.1|refseq:XP_016883701.1|refseq:XP_016883702.1|refseq:XP_016883703.1|refseq:XP_016883704.1|refseq:XP_016883705.1|refseq:XP_016883706.1|refseq:XP_016883707.1|refseq:XP_016883978.1|refseq:XP_016883979.1|refseq:XP_016883980.1|refseq:XP_016883981.1|entrezgene/locuslink:875(identity)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	-	-	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:f9eo0cPOHppVY7Nqejag3YyK18s9606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:AD8159DDFCF219D5|rigid:ADANlPLz4St9Yu5ZB2FdFPX9NCA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32502	uniprotkb:P20591	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	intact:EBI-929476|uniprotkb:D3DSI8|uniprotkb:B2RDA5|uniprotkb:B3KU10|uniprotkb:C9IYV7|uniprotkb:C9J8D6|uniprotkb:C9JN19|uniprotkb:C9JN88|uniprotkb:C9JUL1|uniprotkb:C9JZS6|uniprotkb:Q86YP5|uniprotkb:Q96CI3|ensembl:ENSP00000381599|ensembl:ENSP00000381601|ensembl:ENSP00000392151|ensembl:ENSP00000402215|ensembl:ENSP00000408498|ensembl:ENSP00000410523|ensembl:ENSP00000505029|ensembl:ENSP00000505047|ensembl:ENSP00000505051|ensembl:ENSP00000505189|ensembl:ENSP00000505457|ensembl:ENSP00000505489|ensembl:ENSP00000505630|ensembl:ENSP00000505657|ensembl:ENSP00000505669|ensembl:ENSP00000505781|ensembl:ENSP00000505874|ensembl:ENSP00000506047|ensembl:ENSP00000506062|ensembl:ENSP00000506183|ensembl:ENSP00000506199|ensembl:ENSP00000506220|ensembl:ENSP00000506270|ensembl:ENSP00000506348|ensembl:ENSP00000506372|ensembl:ENSP00000506395|ensembl:ENSP00000506481|ensembl:ENSP00000506512|ensembl:ENSP00000506690|ensembl:ENSP00000506712	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:mx1_human(display_long)|uniprotkb:MX1(gene name)|psi-mi:MX1(display_short)|uniprotkb:Myxovirus resistance protein 1(gene name synonym)|uniprotkb:Interferon-regulated resistance GTP-binding protein MxA(gene name synonym)|uniprotkb:Interferon-induced protein p78(gene name synonym)|uniprotkb:Myxoma resistance protein 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11541153|imex:IM-24995-1980	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	refseq:NP_001269849.1|refseq:NP_001138397.1|refseq:NP_001171517.1|refseq:NP_002453.2|refseq:XP_011527870.1|refseq:XP_005261037.1|refseq:XP_005261038.1|refseq:XP_005261039.1|refseq:XP_005261035.1|refseq:XP_005261036.1|refseq:XP_016883838.1|refseq:XP_016883839.1|dip:DIP-35694N|ensembl:ENSG00000157601(gene)|ensembl:ENST00000398598(transcript)|ensembl:ENST00000398600(transcript)|ensembl:ENST00000413778(transcript)|ensembl:ENST00000417963(transcript)|ensembl:ENST00000419044(transcript)|ensembl:ENST00000455164(transcript)|ensembl:ENST00000679445(transcript)|ensembl:ENST00000679464(transcript)|ensembl:ENST00000679543(transcript)|ensembl:ENST00000679626(transcript)|ensembl:ENST00000679705(transcript)|ensembl:ENST00000679911(transcript)|ensembl:ENST00000680176(transcript)|ensembl:ENST00000680182(transcript)|ensembl:ENST00000680347(transcript)|ensembl:ENST00000680364(transcript)|ensembl:ENST00000680536(transcript)|ensembl:ENST00000680629(transcript)|ensembl:ENST00000680760(transcript)|ensembl:ENST00000680776(transcript)|ensembl:ENST00000681039(transcript)|ensembl:ENST00000681191(transcript)|ensembl:ENST00000681266(transcript)|ensembl:ENST00000681415(transcript)|ensembl:ENST00000681607(transcript)|ensembl:ENST00000681671(transcript)|ensembl:ENST00000681849(transcript)|ensembl:ENST00000681857(transcript)|ensembl:ENST00000681867(transcript)|ensembl:ENST00000681896(transcript)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0003374"(dynamin family protein polymerization involved in mitochondrial fission)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0006952"(defense response)|go:"GO:0007165"(signal transduction)|go:"GO:0008017"(microtubule binding)|go:"GO:0009615"(response to virus)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016185"(synaptic vesicle budding from presynaptic endocytic zone membrane)|go:"GO:0030424"(axon)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031623"(receptor internalization)|go:"GO:0031965"(nuclear membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0034340"(response to type I interferon)|go:"GO:0042802"(identical protein binding)|go:"GO:0044327"(dendritic spine head)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0051607"(defense response to virus)|go:"GO:0061025"(membrane fusion)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:0098793"(presynapse)|go:"GO:0098844"(postsynaptic endocytic zone membrane)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:0140374"(antiviral innate immune response)|interpro:IPR000375(Dynamin central region)|interpro:IPR001401(Dynamin, GTPase region)|interpro:IPR003130(Dynamin GTPase effector)|interpro:IPR019762|interpro:IPR020850|interpro:IPR022812|interpro:IPR027417|interpro:IPR030381|mint:P20591|rcsb pdb:3LJB|rcsb pdb:3SZR|rcsb pdb:3ZYS|rcsb pdb:4P4S|rcsb pdb:4P4T|rcsb pdb:4P4U|rcsb pdb:5GTM|reactome:R-HSA-1169408|reactome:R-HSA-909733|entrezgene/locuslink:4599(identity)	-	crc64:A5409FAF1594854C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	rogid:9rO7Zyl6v0Kq3xw6MKbVefk1hCA9606	intact-crc:1923E75F76B25B0C|rigid:zxPv0WONMV/801GzpWcMFh0tNEk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48775	uniprotkb:P32502	intact:EBI-743494|ensembl:ENSP00000444788|ensembl:ENSP00000460086|uniprotkb:A8K053	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:t23o_human(display_long)|uniprotkb:Tryptophan pyrrolase(gene name synonym)|uniprotkb:Tryptophan oxygenase(gene name synonym)|uniprotkb:Tryptamin 2,3-dioxygenase(gene name synonym)|uniprotkb:TDO2(gene name)|psi-mi:TDO2(display_short)|uniprotkb:TDO(gene name synonym)|uniprotkb:Tryptophanase(gene name synonym)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11541199|imex:IM-24995-1985	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000151790(gene)|ensembl:ENSG00000262635(gene)|ensembl:ENST00000536354(transcript)|ensembl:ENST00000573403(transcript)|go:"GO:0004833"(tryptophan 2,3-dioxygenase activity)|go:"GO:0005829"(cytosol)|go:"GO:0016597"(amino acid binding)|go:"GO:0019441"(tryptophan catabolic process to kynurenine)|go:"GO:0019442"(tryptophan catabolic process to acetyl-CoA)|go:"GO:0019825"(oxygen binding)|go:"GO:0020037"(heme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051289"(protein homotetramerization)|go:"GO:1904842"(response to nitroglycerin)|interpro:IPR004981(Tryptophan 2,3-dioxygenase)|interpro:IPR037217|mint:P48775|rcsb pdb:4PW8|rcsb pdb:5TI9|rcsb pdb:5TIA|rcsb pdb:6A4I|rcsb pdb:6PYY|rcsb pdb:6PYZ|rcsb pdb:6UD5|rcsb pdb:6VBN|reactome:R-HSA-71240|refseq:NP_005642.1|entrezgene/locuslink:6999(identity)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	-	-	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:S+cyc710I52nIFQWgKhXFul9QZw9606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:5C1D14F08F084498|rigid:ppffcJhnWTZPhNOu91xniZ0FcvE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32502	uniprotkb:P43365	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	intact:EBI-749530|uniprotkb:Q9NSD3|intact:EBI-10178394|uniprotkb:Q6FHH8|ensembl:ENSP00000350592|ensembl:ENSP00000377447|ensembl:ENSP00000377478	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:magac_human(display_long)|uniprotkb:MAGE-12 antigen(gene name synonym)|uniprotkb:MAGE12F antigen(gene name synonym)|uniprotkb:Cancer/testis antigen 1.12(gene name synonym)|uniprotkb:MAGEA12(gene name)|psi-mi:MAGEA12(display_short)|uniprotkb:MAGE12(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11541190|imex:IM-24995-1984	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	refseq:NP_001159858.1|refseq:NP_001159859.1|refseq:NP_005358.2|ensembl:ENSG00000213401(gene)|ensembl:ENST00000357916(transcript)|ensembl:ENST00000393869(transcript)|ensembl:ENST00000393900(transcript)|interpro:IPR002190(MAGE protein)|interpro:IPR021072|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|entrezgene/locuslink:4111(identity)	-	crc64:A5409FAF1594854C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	rogid:3/Jxz2VsFOb67RWqWj3xbTrw3s49606	intact-crc:8FA6486E6BDC7A9D|rigid:6eAeGA0x7ECNoUuCK2qW0T7OZ8Y	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32502	uniprotkb:P43356	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	intact:EBI-5650739|uniprotkb:A8K328|uniprotkb:Q32NC6|ensembl:ENSP00000333487|ensembl:ENSP00000359316|ensembl:ENSP00000469919|ensembl:ENSP00000470872|ensembl:ENSP00000480491|ensembl:ENSP00000480738|ensembl:ENSP00000484290|ensembl:ENSP00000485391|ensembl:ENSP00000485541|ensembl:ENSP00000507594|ensembl:ENSP00000507899	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:maga2_human(display_long)|uniprotkb:MAGEA2(gene name)|psi-mi:MAGEA2(display_short)|uniprotkb:MAGEA2B(gene name)|psi-mi:MAGEA2B(display_short)|uniprotkb:MAGE2(gene name synonym)|uniprotkb:MAGEA2A(gene name synonym)|uniprotkb:MAGE2(gene name synonym)|uniprotkb:MAGEA2(gene name synonym)|uniprotkb:Cancer/testis antigen 1.2(gene name synonym)|uniprotkb:MAGE-2 antigen(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11541181|imex:IM-24995-1983	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	refseq:NP_001269430.1|refseq:NP_001269431.1|refseq:NP_001269433.1|refseq:NP_001269434.1|refseq:NP_001308329.1|refseq:NP_001308330.1|refseq:NP_001308331.1|refseq:NP_001308332.1|refseq:NP_001308333.1|refseq:NP_005352.1|refseq:NP_705692.1|refseq:NP_786884.1|refseq:NP_786885.1|dip:DIP-61231N|refseq:XP_016884895.1|refseq:XP_016885008.1|ensembl:ENSG00000183305(gene)|ensembl:ENSG00000268606(gene)|ensembl:ENST00000331220(transcript)|ensembl:ENST00000370293(transcript)|ensembl:ENST00000595583(transcript)|ensembl:ENST00000598543(transcript)|ensembl:ENST00000611557(transcript)|ensembl:ENST00000611674(transcript)|ensembl:ENST00000620710(transcript)|ensembl:ENST00000623438(transcript)|ensembl:ENST00000623806(transcript)|ensembl:ENST00000682532(transcript)|ensembl:ENST00000684311(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0016605"(PML body)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0033234"(negative regulation of protein sumoylation)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0044257"(cellular protein catabolic process)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0072331"(signal transduction by p53 class mediator)|go:"GO:0090398"(cellular senescence)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901984"(negative regulation of protein acetylation)|interpro:IPR002190(MAGE protein)|interpro:IPR021072|interpro:IPR030103|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|entrezgene/locuslink:266740(identity)	-	crc64:A5409FAF1594854C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	rogid:aYv4+irEk9vGE2f3yZQR8hCQGec9606	intact-crc:0686D920B81FB3EC|rigid:4uhle33EU3ueWB3NIALf2R+j2dM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P61289	uniprotkb:P32502	intact:EBI-355546|uniprotkb:O35563|uniprotkb:P97373|uniprotkb:Q12920|uniprotkb:Q13172|uniprotkb:Q9BQD9|uniprotkb:A8K9A3|ensembl:ENSP00000466794	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:psme3_human(display_long)|uniprotkb:PSME3(gene name)|psi-mi:PSME3(display_short)|uniprotkb:Proteasome activator 28 subunit gamma(gene name synonym)|uniprotkb:Activator of multicatalytic protease subunit 3(gene name synonym)|uniprotkb:11S regulator complex subunit gamma(gene name synonym)|uniprotkb:Ki nuclear autoantigen(gene name synonym)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11541237|imex:IM-24995-1989	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005780.2|refseq:NP_789839.1|ensembl:ENSG00000131467(gene)|ensembl:ENST00000590720(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0008537"(proteasome activator complex)|go:"GO:0010950"(positive regulation of endopeptidase activity)|go:"GO:0016020"(membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0061133"(endopeptidase activator activity)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0097371"(MDM2/MDM4 family protein binding)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR003185(Proteasome activator pa28, REG alpha subunit)|interpro:IPR003186(Proteasome activator pa28, REG beta subunit)|interpro:IPR009077(Proteasome activator pa28, REG alpha/beta subunit)|interpro:IPR036252|interpro:IPR036996|interpro:IPR036997|mint:P61289|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|entrezgene/locuslink:10197(identity)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	-	-	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:6EQY2Kj3Juf++m4eBDzPWMgbC2k9606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:946D5CFE1B7DD0D3|rigid:QW7H1v5iA2hK7wS1iphn9qRlhQg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32502	uniprotkb:P56279	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	intact:EBI-749995|uniprotkb:Q6IBK7|ensembl:ENSP00000385036|ensembl:ENSP00000450496|ensembl:ENSP00000450701|ensembl:ENSP00000451506	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:tcl1a_human(display_long)|uniprotkb:Protein p14 TCL1(gene name synonym)|uniprotkb:Oncogene TCL-1(gene name synonym)|uniprotkb:TCL1A(gene name)|psi-mi:TCL1A(display_short)|uniprotkb:TCL1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11541228|imex:IM-24995-1988	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	refseq:NP_001092195.1|refseq:NP_068801.1|refseq:XP_016877165.1|refseq:XP_016877166.1|dip:DIP-60787N|ensembl:ENSG00000100721(gene)|ensembl:ENST00000402399(transcript)|ensembl:ENST00000554012(transcript)|ensembl:ENST00000555202(transcript)|ensembl:ENST00000556450(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010918"(positive regulation of mitochondrial membrane potential)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|interpro:IPR004832(TCL1/MTCP1)|interpro:IPR036672|rcsb pdb:1JSG|entrezgene/locuslink:8115(identity)	-	crc64:A5409FAF1594854C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	rogid:c3GIYkYNb+wWlxn59oU2vpvbfhI9606	intact-crc:DCEA62D3E70C593C|rigid:CIW6CN8FzBdRzFyhwkSFg435ROc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P55212	uniprotkb:P32502	intact:EBI-718729|uniprotkb:Q9BQE7|ensembl:ENSP00000265164	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:casp6_human(display_long)|uniprotkb:Apoptotic protease Mch-2(gene name synonym)|uniprotkb:CASP6(gene name)|psi-mi:CASP6(display_short)|uniprotkb:MCH2(gene name synonym)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11541219|imex:IM-24995-1987	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001217.2|refseq:NP_116787.1|rcsb pdb:3K7E|rcsb pdb:3NKF|rcsb pdb:3NR2|rcsb pdb:3OD5|rcsb pdb:3P45|rcsb pdb:3P4U|rcsb pdb:3QNW|rcsb pdb:3S70|rcsb pdb:3S8E|rcsb pdb:3V6L|rcsb pdb:3V6M|rcsb pdb:4EJF|rcsb pdb:4FXO|rcsb pdb:4HVA|rcsb pdb:4IYR|rcsb pdb:4N5D|rcsb pdb:4N6G|rcsb pdb:4N7J|rcsb pdb:4N7M|rcsb pdb:4NBK|rcsb pdb:4NBL|rcsb pdb:4NBN|rcsb pdb:6DEU|rcsb pdb:6DEV|reactome:R-HSA-111465|reactome:R-HSA-264870|reactome:R-HSA-352238|reactome:R-HSA-6803207|ensembl:ENSG00000138794(gene)|ensembl:ENST00000265164(transcript)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006508"(proteolysis)|go:"GO:0006915"(apoptotic process)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0072734"(cellular response to staurosporine)|go:"GO:0097153"(cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0097200"(cysteine-type endopeptidase activity involved in execution phase of apoptosis)|interpro:IPR001309(Peptidase C14, ICE, catalytic subunit p20)|interpro:IPR002138(Peptidase C14, caspase non-catalytic subunit p10)|interpro:IPR002398(Peptidase C14, caspase precursor p45)|interpro:IPR015917(Peptidase C14, caspase precursor p45, core)|interpro:IPR016129(Peptidase C14, ICE, catalytic subunit p20, active site)|interpro:IPR029030|interpro:IPR033139|interpro:IPR037554|mint:P55212|rcsb pdb:1MI9|rcsb pdb:2WDP|dip:DIP-44649N|entrezgene/locuslink:839(identity)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	-	-	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:x335dTT6omZBrEGs7jzxOjUWaNM9606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:F68E7FC7EAE7A8BF|rigid:dfY8xgiMbt4rskxNsX0THjbpt1I	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49247	uniprotkb:P32502	intact:EBI-744831|uniprotkb:Q541P9|uniprotkb:Q96BJ6|ensembl:ENSP00000283646	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:rpia_human(display_long)|uniprotkb:Phosphoriboisomerase(gene name synonym)|uniprotkb:RPIA(gene name)|psi-mi:RPIA(display_short)|uniprotkb:RPI(gene name synonym)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11541208|imex:IM-24995-1986	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_653164.2|ensembl:ENSG00000153574(gene)|ensembl:ENST00000283646(transcript)|go:"GO:0004751"(ribose-5-phosphate isomerase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006014"(D-ribose metabolic process)|go:"GO:0006098"(pentose-phosphate shunt)|go:"GO:0009052"(pentose-phosphate shunt, non-oxidative branch)|go:"GO:0019693"(ribose phosphate metabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048029"(monosaccharide binding)|interpro:IPR004788(Ribose 5-phosphate isomerase)|interpro:IPR020672|interpro:IPR037171|mint:P49247|reactome:R-HSA-5659996|reactome:R-HSA-6791461|reactome:R-HSA-71336|entrezgene/locuslink:22934(identity)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	-	-	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:gddu0Xp/dx4JwbFMs50pQCvvbws9606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:5DDD1BCD3A58A089|rigid:FIQgDE5w8ZRTYm40k7VpBlc0dhA	false	sufficient binding region:75-311	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q00796	uniprotkb:P32502	intact:EBI-750068|uniprotkb:B2R655|uniprotkb:Q16682|uniprotkb:Q9UMD6|uniprotkb:B7Z3A6|uniprotkb:J3JZZ5|ensembl:ENSP00000267814	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:dhso_human(display_long)|uniprotkb:L-iditol 2-dehydrogenase(gene name synonym)|uniprotkb:SORD(gene name)|psi-mi:SORD(display_short)|uniprotkb:"(R,R)-butanediol dehydrogenase"(gene name synonym)|uniprotkb:Polyol dehydrogenase(gene name synonym)|uniprotkb:Ribitol dehydrogenase(gene name synonym)|uniprotkb:Xylitol dehydrogenase(gene name synonym)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11541273|imex:IM-24995-1993	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003095.2|ensembl:ENSG00000140263(gene)|ensembl:ENST00000267814(transcript)|go:"GO:0000721"("(R,R)-butanediol dehydrogenase activity")|go:"GO:0003939"(L-iditol 2-dehydrogenase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006062"(sorbitol catabolic process)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009725"(response to hormone)|go:"GO:0016020"(membrane)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0031514"(motile cilium)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0046370"(fructose biosynthetic process)|go:"GO:0046526"(D-xylulose reductase activity)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0046688"(response to copper ion)|go:"GO:0050255"(ribitol 2-dehydrogenase activity)|go:"GO:0051160"(L-xylitol catabolic process)|go:"GO:0051164"(L-xylitol metabolic process)|go:"GO:0051287"(NAD binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002328(Alcohol dehydrogenase, zinc-containing, conserved site)|interpro:IPR011032(GroES-like)|interpro:IPR013149(Alcohol dehydrogenase, zinc-binding)|interpro:IPR013154(Alcohol dehydrogenase GroES-like)|interpro:IPR020843|interpro:IPR036291|mint:Q00796|rcsb pdb:1PL6|rcsb pdb:1PL7|rcsb pdb:1PL8|reactome:R-HSA-5652227|reactome:R-HSA-5661270|entrezgene/locuslink:6652(identity)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	-	-	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:BGqvXy2I7nmCLPYTOkUcQ8fpCkk9606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:A460438A2EBEED6E|rigid:WUFHFrW4kPfzg2PwNlplkSvfOcI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P98170	uniprotkb:P32502	intact:EBI-517127|uniprotkb:Q9NQ14|uniprotkb:D3DTF2|ensembl:ENSP00000347858|ensembl:ENSP00000360242|ensembl:ENSP00000395230	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:xiap_human(display_long)|uniprotkb:Inhibitor of apoptosis protein 3(gene name synonym)|uniprotkb:X-linked inhibitor of apoptosis protein(gene name synonym)|uniprotkb:IAP-like protein(gene name synonym)|uniprotkb:XIAP(gene name)|psi-mi:XIAP(display_short)|uniprotkb:API3(gene name synonym)|uniprotkb:IAP3(gene name synonym)|uniprotkb:BIRC4(gene name synonym)|uniprotkb:Baculoviral IAP repeat-containing protein 4(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase XIAP(gene name synonym)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11541264|imex:IM-24995-1992	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006724817.1|refseq:NP_001158.2|refseq:NP_001191330.1|refseq:XP_011529631.1|dip:DIP-27626N|ensembl:ENSG00000101966(gene)|ensembl:ENST00000355640(transcript)|ensembl:ENST00000371199(transcript)|ensembl:ENST00000434753(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005876"(spindle microtubule)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030510"(regulation of BMP signaling pathway)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0055070"(copper ion homeostasis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070424"(regulation of nucleotide-binding oligomerization domain containing signaling pathway)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:1902530"(positive regulation of protein linear polyubiquitination)|go:"GO:1990001"(inhibition of cysteine-type endopeptidase activity involved in apoptotic process)|interpro:IPR001370(Proteinase inhibitor I32, inhibitor of apoptosis)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011029(DEATH-like)|interpro:IPR042579|mint:P98170|rcsb pdb:1C9Q|rcsb pdb:1F9X|rcsb pdb:1G3F|rcsb pdb:1G73|rcsb pdb:1I3O|rcsb pdb:1I4O|rcsb pdb:1I51|rcsb pdb:1KMC|rcsb pdb:1NW9|rcsb pdb:1TFQ|rcsb pdb:1TFT|rcsb pdb:2ECG|rcsb pdb:2JK7|rcsb pdb:2KNA|rcsb pdb:2OPY|rcsb pdb:2OPZ|rcsb pdb:2POI|rcsb pdb:2POP|rcsb pdb:2QRA|rcsb pdb:2VSL|rcsb pdb:3CLX|rcsb pdb:3CM2|rcsb pdb:3CM7|rcsb pdb:3EYL|rcsb pdb:3G76|rcsb pdb:3HL5|rcsb pdb:3UW4|rcsb pdb:3UW5|rcsb pdb:4EC4|rcsb pdb:4HY0|rcsb pdb:4IC2|rcsb pdb:4IC3|rcsb pdb:4J3Y|rcsb pdb:4J44|rcsb pdb:4J45|rcsb pdb:4J46|rcsb pdb:4J47|rcsb pdb:4J48|rcsb pdb:4KJU|rcsb pdb:4KJV|rcsb pdb:4KMP|rcsb pdb:4MTZ|rcsb pdb:4OXC|rcsb pdb:4WVS|rcsb pdb:4WVT|rcsb pdb:4WVU|rcsb pdb:5C0K|rcsb pdb:5C0L|rcsb pdb:5C3H|rcsb pdb:5C3K|rcsb pdb:5C7A|rcsb pdb:5C7B|rcsb pdb:5C7C|rcsb pdb:5C7D|rcsb pdb:5C83|rcsb pdb:5C84|rcsb pdb:5M6E|rcsb pdb:5M6F|rcsb pdb:5M6H|rcsb pdb:5M6L|rcsb pdb:5M6M|rcsb pdb:5O6T|rcsb pdb:5OQW|rcsb pdb:6EY2|rcsb pdb:6GJW|rcsb pdb:6QCI|reactome:R-HSA-111459|reactome:R-HSA-111463|reactome:R-HSA-111464|reactome:R-HSA-111469|reactome:R-HSA-3769402|reactome:R-HSA-5213460|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5675482|reactome:R-HSA-8948747|reactome:R-HSA-8948751|reactome:R-HSA-9627069|entrezgene/locuslink:331(identity)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	-	-	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:6eDcOay+c2ZmIAD/pwnCDROBwgM9606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:7EBFC986FC2A40A1|rigid:LhvS0Fwa9VQ4GHPRulcrwvJqPig	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P63279	uniprotkb:P32502	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11541255|imex:IM-24995-1991	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N|entrezgene/locuslink:7329(identity)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	-	-	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:C0C4A1C7A01D2272|rigid:J5OBNYvMFV2v9zhlut1DhG67OVg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32502	uniprotkb:P61457	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	intact:EBI-740475|ensembl:ENSP00000299299|uniprotkb:P70519|uniprotkb:P80095|uniprotkb:Q9D930	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:phs_human(display_long)|uniprotkb:4-alpha-hydroxy-tetrahydropterin dehydratase(gene name synonym)|uniprotkb:Phenylalanine hydroxylase-stimulating protein(gene name synonym)|uniprotkb:Pterin carbinolamine dehydratase(gene name synonym)|uniprotkb:Dimerization cofactor of hepatocyte nuclear factor 1-alpha(gene name synonym)|uniprotkb:PCBD1(gene name)|psi-mi:PCBD1(display_short)|uniprotkb:DCOH(gene name synonym)|uniprotkb:PCBD(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11541246|imex:IM-24995-1990	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	refseq:NP_000272.1|ensembl:ENSG00000166228(gene)|ensembl:ENST00000299299(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004505"(phenylalanine 4-monooxygenase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006558"(L-phenylalanine metabolic process)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0008124"(4-alpha-hydroxytetrahydrobiopterin dehydratase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001533(Transcriptional coactivator/pterin dehydratase)|interpro:IPR036428|mint:P61457|reactome:R-HSA-8964208|refseq:NP_001276726.1|entrezgene/locuslink:5092(identity)	-	crc64:A5409FAF1594854C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	rogid:WsAu8slwInyWOA2p/z+JqTvyKP49606	intact-crc:E66C5715ECCEC582|rigid:ws63suhiisK0D+qYFpMFXmdE6YY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q13155	uniprotkb:P32502	intact:EBI-745226|uniprotkb:Q75MR1|uniprotkb:Q96CZ5|uniprotkb:Q9P1L2|ensembl:ENSP00000223029|uniprotkb:F8W950	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:aimp2_human(display_long)|uniprotkb:Protein JTV-1(gene name synonym)|uniprotkb:AIMP2(gene name)|psi-mi:AIMP2(display_short)|uniprotkb:PRO0992(orf name)|uniprotkb:JTV1(gene name synonym)|uniprotkb:Multisynthase complex auxiliary component p38(gene name synonym)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11541301|imex:IM-24995-1996	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006294.2|ensembl:ENSG00000106305(gene)|ensembl:ENST00000223029(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0006915"(apoptotic process)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0017101"(aminoacyl-tRNA synthetase multienzyme complex)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060510"(type II pneumocyte differentiation)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1903632"(positive regulation of aminoacyl-tRNA ligase activity)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR031889|interpro:IPR036282|interpro:IPR041503|interpro:IPR042360|mint:Q13155|rcsb pdb:4DPG|rcsb pdb:4YCU|rcsb pdb:4YCW|rcsb pdb:5A1N|rcsb pdb:5A34|rcsb pdb:5A5H|rcsb pdb:5Y6L|rcsb pdb:6ILD|rcsb pdb:6IY6|rcsb pdb:6JPV|rcsb pdb:6K39|reactome:R-HSA-2408522|reactome:R-HSA-379716|dip:DIP-34421N|refseq:NP_001313536.1|entrezgene/locuslink:7965(identity)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	-	-	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:VEBmJjo6t3dBY6mKpmUyVLamJFQ9606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:80FDDEFA759B3C43|rigid:F3XDrjB1HkR0VvZZQGaFt+lZ3b0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q13049	uniprotkb:P32502	intact:EBI-742790|ensembl:ENSP00000363095|ensembl:ENSP00000408292|uniprotkb:Q9NQP8	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:tri32_human(display_long)|uniprotkb:Zinc finger protein HT2A(gene name synonym)|uniprotkb:72 kDa Tat-interacting protein(gene name synonym)|uniprotkb:TRIM32(gene name)|psi-mi:TRIM32(display_short)|uniprotkb:HT2A(gene name synonym)|uniprotkb:Tripartite motif-containing protein 32(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM32(gene name synonym)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11541292|imex:IM-24995-1995	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0043621"(protein self-association)|go:"GO:0045087"(innate immune response)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051155"(positive regulation of striated muscle cell differentiation)|go:"GO:0061564"(axon development)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1902187"|go:"GO:1902230"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:1903265"(positive regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:1903883"(positive regulation of interleukin-17-mediated signaling pathway)|go:"GO:1903886"("positive regulation of chemokine (C-C motif) ligand 20 production")|go:"GO:2000147"(positive regulation of cell motility)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENSG00000119401(gene)|ensembl:ENST00000373983(transcript)|ensembl:ENST00000450136(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001894"(tissue homeostasis)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005863"(striated muscle myosin thick filament)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007014"(actin ubiquitination)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009411"(response to UV)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0017022"(myosin binding)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030957"(Tat protein binding)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034612"(response to tumor necrosis factor)|go:"GO:0042802"(identical protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|interpro:IPR000315(Zinc finger, B-box)|refseq:NP_001093149.1|refseq:XP_011516700.1|refseq:NP_036342.2|refseq:XP_005251870.1|interpro:IPR001258(NHL repeat)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR013017(NHL repeat, subgroup)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR027370|mint:Q13049|rcsb pdb:2CT2|rcsb pdb:5FEY|reactome:R-HSA-3134975|reactome:R-HSA-983168|refseq:XP_016869975.1|entrezgene/locuslink:22954(identity)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	-	-	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:XuqprQd10kSpsuyGs+FSdzIdJ/Y9606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:CEBE171A9C1CF000|rigid:rHcMBkLR5Rdd3LnDcpJZingk8vU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q03393	uniprotkb:P32502	intact:EBI-712344|ensembl:ENSP00000280362|uniprotkb:Q8WVG8|uniprotkb:B0YJ87	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:ptps_human(display_long)|uniprotkb:PTS(gene name)|psi-mi:PTS(display_short)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11541282|imex:IM-24995-1994	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000308.1|ensembl:ENSG00000150787(gene)|ensembl:ENST00000280362(transcript)|go:"GO:0003874"(6-pyruvoyltetrahydropterin synthase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006520"(cellular amino acid metabolic process)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0007417"(central nervous system development)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR007115(6-pyruvoyl tetrahydropterin synthase-related)|interpro:IPR022469|interpro:IPR022470|interpro:IPR038418|rcsb pdb:3I2B|reactome:R-HSA-1474151|entrezgene/locuslink:5805(identity)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	-	-	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Qa3bMpzyvRxrvDq9dZUSQlfbpeg9606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:8E492B6A80CE9502|rigid:yR/xKlV7hNDD/Q9EM8NqkgdEspw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q53EZ4	uniprotkb:P32502	intact:EBI-747776|uniprotkb:Q32WF5|uniprotkb:Q3MV20|uniprotkb:Q5VY28|uniprotkb:Q6N034|ensembl:ENSP00000360540|uniprotkb:Q96H32|uniprotkb:Q9NVS7|uniprotkb:B2RDG8|intact:EBI-10173536|uniprotkb:D3DR37|intact:EBI-28973801	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:cep55_human(display_long)|uniprotkb:Up-regulated in colon cancer 6(gene name synonym)|uniprotkb:CEP55(gene name)|psi-mi:CEP55(display_short)|uniprotkb:URCC6(gene name synonym)|uniprotkb:C10orf3(gene name synonym)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11541338|imex:IM-24995-2000	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001120654.1|refseq:NP_060601.3|ensembl:ENSG00000138180(gene)|ensembl:ENST00000371485(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0014066"(regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0030496"(midbody)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042802"(identical protein binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0061952"(midbody abscission)|go:"GO:0090543"(Flemming body)|go:"GO:1904888"(cranial skeletal system development)|interpro:IPR022008|interpro:IPR038926|mint:Q53EZ4|rcsb pdb:3E1R|rcsb pdb:3WUT|rcsb pdb:3WUU|rcsb pdb:3WUV|go:"GO:0005814"(centriole)|ensembl:ENSP00000360540|dip:DIP-44581N|entrezgene/locuslink:55165(identity)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	-	-	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:tuo36vVb8ZgPDR81YjZFNEg559w9606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:1A5EDCE93CF60171|rigid:2kHflvspg2fhw+Zk3atP8GZBmTk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q14749	uniprotkb:P32502	intact:EBI-744239|uniprotkb:Q9NNZ1|uniprotkb:Q9NS24|uniprotkb:Q5T8W2|ensembl:ENSP00000361894	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:gnmt_human(display_long)|uniprotkb:GNMT(gene name)|psi-mi:GNMT(display_short)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11541329|imex:IM-24995-1999	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_061833.1|refseq:NP_001305794.1|ensembl:ENSG00000124713(gene)|ensembl:ENST00000372808(transcript)|go:"GO:0005542"(folic acid binding)|go:"GO:0005829"(cytosol)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0006111"(regulation of gluconeogenesis)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006555"(methionine metabolic process)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0016594"(glycine binding)|go:"GO:0017174"(glycine N-methyltransferase activity)|go:"GO:0032259"(methylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0046498"(S-adenosylhomocysteine metabolic process)|go:"GO:0046500"(S-adenosylmethionine metabolic process)|go:"GO:0051289"(protein homotetramerization)|go:"GO:1901052"(sarcosine metabolic process)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|interpro:IPR014369(Glycine N-methyltransferase)|interpro:IPR029063|interpro:IPR041698|rcsb pdb:1R74|rcsb pdb:2AZT|reactome:R-HSA-2408508|reactome:R-HSA-389661|entrezgene/locuslink:27232(identity)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	-	-	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:noj0nCgjJ1Dq079ycrwAu30a4AU9606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:B358F6F73F159E0C|rigid:8x0vbouDfpgFXpuOOybPIvyDrhI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q13554-3	uniprotkb:P32502	intact:EBI-11523526|ensembl:ENSP00000351542	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:q13554-3(display_long)|uniprotkb:CAMK2B(gene name)|psi-mi:CAMK2B(display_short)|uniprotkb:CAM2(gene name synonym)|uniprotkb:CAMK2(gene name synonym)|uniprotkb:CAMKB(gene name synonym)|uniprotkb:Beta'E(isoform synonym)|uniprotkb:Beta1(isoform synonym)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11541320|imex:IM-24995-1998	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000058404(gene)|ensembl:ENST00000358707(transcript)|intact:EBI-1058722(isoform-parent)|uniprotkb:Q13554-3(isoform-parent)|entrezgene/locuslink:816(identity)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	-	isoform-comment:"Ref.1 (AAD42036) sequence is in conflict in position: 316:A->V."	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:H/SPSRbW/NRcHPJs7Z2y6ESTrhM9606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:3FA1DCB409E4217E|rigid:DKdWSpVJL+VPJ6ZusJRxw/O5DJ4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q13490	uniprotkb:P32502	intact:EBI-514538|uniprotkb:Q16516|uniprotkb:Q4TTG0|uniprotkb:B4E026|ensembl:ENSP00000227758|ensembl:ENSP00000477613	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:birc2_human(display_long)|uniprotkb:Inhibitor of apoptosis protein 2(gene name synonym)|uniprotkb:TNFR2-TRAF-signaling complex protein 2(gene name synonym)|uniprotkb:IAP homolog B(gene name synonym)|uniprotkb:RING finger protein 48(gene name synonym)|uniprotkb:BIRC2(gene name)|psi-mi:BIRC2(display_short)|uniprotkb:API1(gene name synonym)|uniprotkb:MIHB(gene name synonym)|uniprotkb:RNF48(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase BIRC2(gene name synonym)|uniprotkb:Cellular inhibitor of apoptosis 1(gene name synonym)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11541311|imex:IM-24995-1997	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001157.1|refseq:NP_001243095.1|refseq:NP_001243092.1|dip:DIP-33485N|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0045471"(response to ethanol)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051087"(chaperone binding)|go:"GO:0051591"(response to cAMP)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060544"(regulation of necroptotic process)|go:"GO:0060546"(negative regulation of necroptotic process)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070266"(necroptotic process)|go:"GO:0070424"(regulation of nucleotide-binding oligomerization domain containing signaling pathway)|go:"GO:0098770"(FBXO family protein binding)|go:"GO:1901222"(regulation of NIK/NF-kappaB signaling)|go:"GO:1902443"(negative regulation of ripoptosome assembly involved in necroptotic process)|go:"GO:1902523"(positive regulation of protein K63-linked ubiquitination)|go:"GO:1902524"(positive regulation of protein K48-linked ubiquitination)|go:"GO:1902527"(positive regulation of protein monoubiquitination)|go:"GO:2000116"(regulation of cysteine-type endopeptidase activity)|go:"GO:2000377"(regulation of reactive oxygen species metabolic process)|interpro:IPR001315(Caspase Recruitment)|interpro:IPR001370(Proteinase inhibitor I32, inhibitor of apoptosis)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011029(DEATH-like)|interpro:IPR041933|mint:Q13490|rcsb pdb:1QBH|rcsb pdb:2L9M|rcsb pdb:3D9T|rcsb pdb:3D9U|rcsb pdb:3M1D|rcsb pdb:3MUP|rcsb pdb:3OZ1|rcsb pdb:3T6P|rcsb pdb:3UW4|rcsb pdb:4EB9|rcsb pdb:4HY4|rcsb pdb:4HY5|rcsb pdb:4KMN|rcsb pdb:4LGE|rcsb pdb:4LGU|rcsb pdb:4MTI|rcsb pdb:4MU7|rcsb pdb:5M6N|rcsb pdb:6EXW|rcsb pdb:6HPR|rcsb pdb:6W74|rcsb pdb:6W7O|rcsb pdb:6W8I|reactome:R-HSA-111465|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-5213460|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5668541|reactome:R-HSA-5675482|reactome:R-HSA-5676594|reactome:R-HSA-5689880|reactome:R-HSA-937041|ensembl:ENSG00000110330(gene)|ensembl:ENST00000227758(transcript)|ensembl:ENST00000613397(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001741"(XY body)|go:"GO:0001890"(placenta development)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0016740"(transferase activity)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034121"(regulation of toll-like receptor signaling pathway)|go:"GO:0035631"(CD40 receptor complex)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0039535"(regulation of RIG-I signaling pathway)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|entrezgene/locuslink:329(identity)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	-	-	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:FOikzyDyDtlv2l69i/WNDNq674A9606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:BF2A3158072F5EFF|rigid:OzX/AG4aATDjYDYDEi8FO1Y3P2g	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32502	uniprotkb:Q5JR59-3	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	intact:EBI-11522433|ensembl:ENSP00000370186	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:q5jr59-3(display_long)|uniprotkb:MTUS2(gene name)|psi-mi:MTUS2(display_short)|uniprotkb:CAZIP(gene name synonym)|uniprotkb:Cardiac zipper protein(gene name synonym)|uniprotkb:KIAA0774(gene name synonym)|uniprotkb:Microtubule plus-end tracking protein TIP150(gene name synonym)|uniprotkb:TIP150(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11541356|imex:IM-24995-2002	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	ensembl:ENSG00000132938(gene)|ensembl:ENST00000380808(transcript)|intact:EBI-742948(isoform-parent)|uniprotkb:Q5JR59-3(isoform-parent)|entrezgene/locuslink:23281(identity)	-	crc64:A5409FAF1594854C	isoform-comment:No experimental confirmation available.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	rogid:npId9tC7VoLN/jteoBiRbSYChPs9606	intact-crc:8B1A50537950B0FB|rigid:TOLzTALWlWRNyacE8+VOm+bAeFA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q53G59	uniprotkb:P32502	intact:EBI-740929|ensembl:ENSP00000356230|uniprotkb:A6NEN8|uniprotkb:B7Z7B8|uniprotkb:Q9HBX5	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:klh12_human(display_long)|uniprotkb:CUL3-interacting protein 1(gene name synonym)|uniprotkb:KLHL12(gene name)|psi-mi:KLHL12(display_short)|uniprotkb:C3IP1(gene name synonym)|uniprotkb:DKIR homolog(gene name synonym)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11541347|imex:IM-24995-2001	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048208"(COPII vesicle coating)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR017096(Kelch-like protein, gigaxonin)|mint:Q53G59|rcsb pdb:2VPJ|rcsb pdb:6TTK|rcsb pdb:6V7O|reactome:R-HSA-4641258|refseq:NP_067646.1|ensembl:ENSG00000117153(gene)|ensembl:ENST00000367261(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0014029"(neural crest formation)|go:"GO:0014032"(neural crest cell development)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0034451"(centriolar satellite)|refseq:NP_001289980.1|refseq:NP_001290038.1|entrezgene/locuslink:59349(identity)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	-	-	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:C4I/Ys9vqNqfG61HsXRZhywP4vE9606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:D7C91DFA1A105D77|rigid:QkZKqnQnfaRcRbHr7Uib0bBlOJ8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9BQD3	uniprotkb:P40368	intact:EBI-739657|uniprotkb:O76098|ensembl:ENSP00000472678|ensembl:ENSP00000472836|ensembl:ENSP00000222307|ensembl:ENSP00000438903|ensembl:ENSP00000443549|ensembl:ENSP00000468990|ensembl:ENSP00000471554	intact:EBI-12331|ensemblfungi:YJL061W|uniprotkb:D6VWC1	psi-mi:kxdl1_human(display_long)|uniprotkb:KXD1(gene name)|psi-mi:KXD1(display_short)|uniprotkb:C19orf50(gene name synonym)	psi-mi:nup82_yeast(display_long)|uniprotkb:NUP82(gene name)|psi-mi:NUP82(display_short)|uniprotkb:YJL061W(locus name)|uniprotkb:J1135(orf name)|uniprotkb:HRB187(orf name)|uniprotkb:Nuclear pore protein NUP82(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11541365|imex:IM-24995-2003	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001165419.1|refseq:NP_001165420.1|refseq:NP_076974.2|ensembl:ENST00000222307(transcript)|ensembl:ENST00000539106(transcript)|ensembl:ENST00000540691(transcript)|ensembl:ENST00000595073(transcript)|ensembl:ENST00000599319(transcript)|ensembl:ENST00000600654(transcript)|ensembl:ENST00000602094(transcript)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0032418"(lysosome localization)|go:"GO:0099078"(BORC complex)|interpro:IPR019371|interpro:IPR039843|ensembl:ENSG00000105700(gene)|refseq:XP_016882770.1|refseq:XP_011526574.1|refseq:XP_011526575.1|refseq:XP_006722946.1|entrezgene/locuslink:79036(identity)	refseq:NP_012474.1|sgd:S000003597|ensemblfungi:YJL061W(gene)|ensemblfungi:YJL061W_mRNA(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0005634"(nucleus)|interpro:IPR037700|rcsb pdb:3PBP|rcsb pdb:3TKN|go:"GO:0005643"(nuclear pore)|go:"GO:0005829"(cytosol)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0044612"(nuclear pore linkers)|go:"GO:0044614"(nuclear pore cytoplasmic filaments)|mint:P40368|dip:DIP-913N|sgd:YJL061W(identity)	-	-	crc64:C379B5E111E26B50	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:5BoR6AN0Ywb1eI04Rw4chmlWVI09606	rogid:g1+jqOMmde8phrNI9H7nFlXwjH0559292	intact-crc:725881F6D100D69C|rigid:z+3r6dsLXpSeZpn1SwXxTO88OOM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40454	uniprotkb:O76083-2	intact:EBI-25278|uniprotkb:D6VVD4|ensemblfungi:YIL153W	intact:EBI-11524542|ensembl:ENSP00000335242	psi-mi:ptpa1_yeast(display_long)|uniprotkb:YIL153W(locus name)|uniprotkb:RRD1(gene name)|psi-mi:RRD1(display_short)|uniprotkb:NCS1(gene name synonym)|uniprotkb:YPA1(gene name synonym)|uniprotkb:Peptidyl-prolyl cis-trans isomerase PTPA-1(gene name synonym)|uniprotkb:Phosphotyrosyl phosphatase activator 1(gene name synonym)	psi-mi:o76083-2(display_long)|uniprotkb:PDE9A(gene name)|psi-mi:PDE9A(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11541434|imex:IM-24995-2010	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012113.1|sgd:S000001415|mint:P40454|dip:DIP-5663N|ensemblfungi:YIL153W(gene)|ensemblfungi:YIL153W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006914"(autophagy)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008160"(protein tyrosine phosphatase activator activity)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0043618"(regulation of transcription from RNA polymerase II promoter in response to stress)|interpro:IPR004327(Phosphotyrosyl phosphatase activator, PTPA)|interpro:IPR037218|interpro:IPR043170|rcsb pdb:2IXO|rcsb pdb:2IXP|sgd:YIL153W(identity)	intact:EBI-742764(isoform-parent)|ensembl:ENSG00000160191(gene)|ensembl:ENST00000335512(transcript)|uniprotkb:O76083-2(isoform-parent)|entrezgene/locuslink:5152(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:It2q8WlpmvLEZ1fqpRF5Fypw9Q4559292	rogid:nTzgeYGOwTM/7VJUgxSnlnDiCFo9606	intact-crc:45CEB29982D550E4|rigid:BXZw2vFztuNWbIemzOgAazbzMhk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40454	uniprotkb:O15156-2	intact:EBI-25278|uniprotkb:D6VVD4|ensemblfungi:YIL153W	intact:EBI-11522250|ensembl:ENSP00000406286	psi-mi:ptpa1_yeast(display_long)|uniprotkb:YIL153W(locus name)|uniprotkb:RRD1(gene name)|psi-mi:RRD1(display_short)|uniprotkb:NCS1(gene name synonym)|uniprotkb:YPA1(gene name synonym)|uniprotkb:Peptidyl-prolyl cis-trans isomerase PTPA-1(gene name synonym)|uniprotkb:Phosphotyrosyl phosphatase activator 1(gene name synonym)	psi-mi:o15156-2(display_long)|uniprotkb:ZBTB7B(gene name)|psi-mi:ZBTB7B(display_short)|uniprotkb:Krueppel-related zinc finger protein cKrox(gene name synonym)|uniprotkb:T-helper-inducing POZ/Krueppel-like factor(gene name synonym)|uniprotkb:ZBTB15(gene name synonym)|uniprotkb:ZFP67(gene name synonym)|uniprotkb:ZNF857B(gene name synonym)|uniprotkb:Zinc finger and BTB domain-containing protein 15(gene name synonym)|uniprotkb:Zinc finger protein 67 homolog(gene name synonym)|uniprotkb:Zinc finger protein 857B(gene name synonym)|uniprotkb:Zinc finger protein Th-POK(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11541423|imex:IM-24995-2009	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012113.1|sgd:S000001415|mint:P40454|dip:DIP-5663N|ensemblfungi:YIL153W(gene)|ensemblfungi:YIL153W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006914"(autophagy)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008160"(protein tyrosine phosphatase activator activity)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0043618"(regulation of transcription from RNA polymerase II promoter in response to stress)|interpro:IPR004327(Phosphotyrosyl phosphatase activator, PTPA)|interpro:IPR037218|interpro:IPR043170|rcsb pdb:2IXO|rcsb pdb:2IXP|sgd:YIL153W(identity)	intact:EBI-740434(isoform-parent)|ensembl:ENSG00000160685(gene)|ensembl:ENST00000417934(transcript)|uniprotkb:O15156-2(isoform-parent)|entrezgene/locuslink:51043(identity)	-	-	isoform-comment:No experimental confirmation available.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:It2q8WlpmvLEZ1fqpRF5Fypw9Q4559292	rogid:41NEFYyprTXI+fOHVFh78TPKF289606	intact-crc:35E70C05541EACA2|rigid:Mt7Tv9gZQn2oR/jTpxqKaeswQOg	false	-	sufficient binding region:35-573	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40454	uniprotkb:G5E962	intact:EBI-25278|uniprotkb:D6VVD4|ensemblfungi:YIL153W	intact:EBI-11525615|ensembl:ENSP00000328177	psi-mi:ptpa1_yeast(display_long)|uniprotkb:YIL153W(locus name)|uniprotkb:RRD1(gene name)|psi-mi:RRD1(display_short)|uniprotkb:NCS1(gene name synonym)|uniprotkb:YPA1(gene name synonym)|uniprotkb:Peptidyl-prolyl cis-trans isomerase PTPA-1(gene name synonym)|uniprotkb:Phosphotyrosyl phosphatase activator 1(gene name synonym)	psi-mi:g5e962_human(display_long)|uniprotkb:hCG_1644200(orf name)|uniprotkb:MAGEA11(gene name)|psi-mi:MAGEA11(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11541412|imex:IM-24995-2008	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012113.1|sgd:S000001415|mint:P40454|dip:DIP-5663N|ensemblfungi:YIL153W(gene)|ensemblfungi:YIL153W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006914"(autophagy)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008160"(protein tyrosine phosphatase activator activity)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0043618"(regulation of transcription from RNA polymerase II promoter in response to stress)|interpro:IPR004327(Phosphotyrosyl phosphatase activator, PTPA)|interpro:IPR037218|interpro:IPR043170|rcsb pdb:2IXO|rcsb pdb:2IXP|sgd:YIL153W(identity)	refseq:NP_001011544.1|ensembl:ENSG00000185247(gene)|ensembl:ENST00000333104(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016604"(nuclear body)|interpro:IPR002190(MAGE protein)|interpro:IPR021072|interpro:IPR030099|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|entrezgene/locuslink:4110(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:It2q8WlpmvLEZ1fqpRF5Fypw9Q4559292	rogid:sVB0aA6yibWUx/d2SE+pwpKKgtI9606	intact-crc:8F7D693DF48DD799|rigid:KsVct/YV1zMOa+Ebr+FAG0MIZPE	false	-	sufficient binding region:82-400	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40454	uniprotkb:A2A369	intact:EBI-25278|uniprotkb:D6VVD4|ensemblfungi:YIL153W	intact:EBI-11530808|ensembl:ENSP00000371766	psi-mi:ptpa1_yeast(display_long)|uniprotkb:YIL153W(locus name)|uniprotkb:RRD1(gene name)|psi-mi:RRD1(display_short)|uniprotkb:NCS1(gene name synonym)|uniprotkb:YPA1(gene name synonym)|uniprotkb:Peptidyl-prolyl cis-trans isomerase PTPA-1(gene name synonym)|uniprotkb:Phosphotyrosyl phosphatase activator 1(gene name synonym)	psi-mi:a2a369_human(display_long)|uniprotkb:DOCK8(gene name)|psi-mi:DOCK8(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11541401|imex:IM-24995-2007	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012113.1|sgd:S000001415|mint:P40454|dip:DIP-5663N|ensemblfungi:YIL153W(gene)|ensemblfungi:YIL153W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006914"(autophagy)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008160"(protein tyrosine phosphatase activator activity)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0043618"(regulation of transcription from RNA polymerase II promoter in response to stress)|interpro:IPR004327(Phosphotyrosyl phosphatase activator, PTPA)|interpro:IPR037218|interpro:IPR043170|rcsb pdb:2IXO|rcsb pdb:2IXP|sgd:YIL153W(identity)	ensembl:ENSG00000107099(gene)|ensembl:ENST00000382329(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0007264"(small GTPase mediated signal transduction)|interpro:IPR010703(Dedicator of cytokinesis)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026791|interpro:IPR027007|interpro:IPR027357|interpro:IPR035892|interpro:IPR043161|interpro:IPR043162|entrezgene/locuslink:81704(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:It2q8WlpmvLEZ1fqpRF5Fypw9Q4559292	rogid:Sa5ulmmVxrpxZ+GAhN64RAHXYdk9606	intact-crc:5F2ECF3B64AEF72E|rigid:BRPqghNdVaxCkDOG5Xsw8yD+iLA	false	-	sufficient binding region:1054-1566	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40446	uniprotkb:Q15645	intact:EBI-11530862|uniprotkb:D6VVC2|uniprotkb:Q05730|ensemblfungi:YIL165C	intact:EBI-358993|uniprotkb:C9K0T3|uniprotkb:O15324|ensembl:ENSP00000166345|uniprotkb:D3DTC0	psi-mi:yiq5_yeast(display_long)|uniprotkb:YI9402.10AC(orf name)|uniprotkb:YIL165C(locus name)	psi-mi:pch2_human(display_long)|uniprotkb:TRIP13(gene name)|psi-mi:TRIP13(display_short)|uniprotkb:Thyroid receptor-interacting protein 13(gene name synonym)|uniprotkb:PCH2(gene name synonym)|uniprotkb:Thyroid hormone receptor interactor 13(gene name synonym)|uniprotkb:Human papillomavirus type 16 E1 protein-binding protein(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11541392|imex:IM-24995-2006	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR003010(Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase)|refseq:NP_012101.1|sgd:S000001427|interpro:IPR044149|ensemblfungi:YIL165C(gene)|ensemblfungi:YIL165C_mRNA(transcript)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0003824"(catalytic activity)|go:"GO:0006807"(nitrogen compound metabolic process)|go:"GO:0016236"(macroautophagy)|interpro:IPR036526|sgd:YIL165C(identity)	refseq:NP_004228.1|ensembl:ENSG00000071539(gene)|ensembl:ENST00000166345(transcript)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|refseq:XP_011512465.1|dip:DIP-34493N|go:"GO:0005694"(chromosome)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0007141"(male meiosis I)|go:"GO:0007144"(female meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007286"(spermatid development)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051598"(meiotic recombination checkpoint signaling)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR027417|interpro:IPR044539|mint:Q15645|rcsb pdb:5VQ9|rcsb pdb:5VQA|rcsb pdb:5WC2|rcsb pdb:6F0X|rcsb pdb:6LK0|rcsb pdb:7L9P|entrezgene/locuslink:9319(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/03/16	rogid:5G/EX7rlenWVlKfGQdYrkSF26Lw559292	rogid:heF2f3R2lGIpZ80mZHnhMktXTE49606	intact-crc:D11133CD6662D33E|rigid:tQ+Lq4y8f+dGePQC1yTsxnbJor4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40368	uniprotkb:Q9Y3C0	intact:EBI-12331|ensemblfungi:YJL061W|uniprotkb:D6VWC1	intact:EBI-712969|ensembl:ENSP00000240079|uniprotkb:Q53FF0|uniprotkb:Q6IAI4|uniprotkb:Q96QK0|uniprotkb:B2RC74	psi-mi:nup82_yeast(display_long)|uniprotkb:NUP82(gene name)|psi-mi:NUP82(display_short)|uniprotkb:YJL061W(locus name)|uniprotkb:J1135(orf name)|uniprotkb:HRB187(orf name)|uniprotkb:Nuclear pore protein NUP82(gene name synonym)	psi-mi:wasc3_human(display_long)|uniprotkb:WASHC3(gene name)|psi-mi:WASHC3(display_short)|uniprotkb:Coiled-coil domain-containing protein 53(gene name synonym)|uniprotkb:AD-016(orf name)|uniprotkb:CCDC53(orf name)|uniprotkb:CGI-116(orf name)|uniprotkb:x0009(orf name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11541383|imex:IM-24995-2005	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012474.1|sgd:S000003597|ensemblfungi:YJL061W(gene)|ensemblfungi:YJL061W_mRNA(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0005634"(nucleus)|interpro:IPR037700|rcsb pdb:3PBP|rcsb pdb:3TKN|go:"GO:0005643"(nuclear pore)|go:"GO:0005829"(cytosol)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0044612"(nuclear pore linkers)|go:"GO:0044614"(nuclear pore cytoplasmic filaments)|mint:P40368|dip:DIP-913N|sgd:YJL061W(identity)	ensembl:ENSG00000120860(gene)|ensembl:ENST00000240079(transcript)|go:"GO:0005769"(early endosome)|go:"GO:0006887"(exocytosis)|go:"GO:0015031"(protein transport)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0071203"(WASH complex)|interpro:IPR019309|mint:Q9Y3C0|refseq:NP_057137.1|entrezgene/locuslink:51019(identity)	-	crc64:C379B5E111E26B50	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:g1+jqOMmde8phrNI9H7nFlXwjH0559292	rogid:jonEQJt0wEcrS2YEiKcmmIiZjCA9606	intact-crc:6CC7419668644966|rigid:+K6/4kcgYqa47kJX3VAfnTyqRmY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9HCM9-2	uniprotkb:P40368	intact:EBI-11523450|ensembl:ENSP00000365847|ensembl:ENSP00000373095|ensembl:ENSP00000373097|ensembl:ENSP00000379797|ensembl:ENSP00000379800|ensembl:ENSP00000383486|ensembl:ENSP00000387445|ensembl:ENSP00000389198|ensembl:ENSP00000389852|ensembl:ENSP00000392130|ensembl:ENSP00000394353|ensembl:ENSP00000396986|ensembl:ENSP00000398956|ensembl:ENSP00000401071|ensembl:ENSP00000401184|ensembl:ENSP00000404340|ensembl:ENSP00000404904|ensembl:ENSP00000411582|ensembl:ENSP00000412743|ensembl:ENSP00000414525|ensembl:ENSP00000415259	intact:EBI-12331|ensemblfungi:YJL061W|uniprotkb:D6VWC1	psi-mi:q9hcm9-2(display_long)|uniprotkb:TRIM39(gene name)|psi-mi:TRIM39(display_short)|uniprotkb:RING finger protein 23(gene name synonym)|uniprotkb:RNF23(gene name synonym)|uniprotkb:TFP(gene name synonym)|uniprotkb:Testis-abundant finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 39(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM39(gene name synonym)|uniprotkb:TIM39beta(isoform synonym)	psi-mi:nup82_yeast(display_long)|uniprotkb:NUP82(gene name)|psi-mi:NUP82(display_short)|uniprotkb:YJL061W(locus name)|uniprotkb:J1135(orf name)|uniprotkb:HRB187(orf name)|uniprotkb:Nuclear pore protein NUP82(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11541374|imex:IM-24995-2004	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-739510(isoform-parent)|ensembl:ENSG00000204599(gene)|ensembl:ENSG00000206495(gene)|ensembl:ENSG00000224994(gene)|ensembl:ENSG00000226437(gene)|ensembl:ENSG00000229929(gene)|ensembl:ENSG00000230308(gene)|ensembl:ENSG00000232839(gene)|ensembl:ENST00000376659(transcript)|ensembl:ENST00000383601(transcript)|ensembl:ENST00000383603(transcript)|ensembl:ENST00000396548(transcript)|ensembl:ENST00000396551(transcript)|ensembl:ENST00000400644(transcript)|ensembl:ENST00000414015(transcript)|ensembl:ENST00000419790(transcript)|ensembl:ENST00000430502(transcript)|ensembl:ENST00000431272(transcript)|ensembl:ENST00000433900(transcript)|ensembl:ENST00000438076(transcript)|ensembl:ENST00000438859(transcript)|ensembl:ENST00000440117(transcript)|ensembl:ENST00000443109(transcript)|ensembl:ENST00000446397(transcript)|ensembl:ENST00000449318(transcript)|ensembl:ENST00000450778(transcript)|ensembl:ENST00000451132(transcript)|ensembl:ENST00000452705(transcript)|ensembl:ENST00000458607(transcript)|uniprotkb:Q9HCM9-2(isoform-parent)|entrezgene/locuslink:56658(identity)	refseq:NP_012474.1|sgd:S000003597|ensemblfungi:YJL061W(gene)|ensemblfungi:YJL061W_mRNA(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0005634"(nucleus)|interpro:IPR037700|rcsb pdb:3PBP|rcsb pdb:3TKN|go:"GO:0005643"(nuclear pore)|go:"GO:0005829"(cytosol)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0044612"(nuclear pore linkers)|go:"GO:0044614"(nuclear pore cytoplasmic filaments)|mint:P40368|dip:DIP-913N|sgd:YJL061W(identity)	-	-	crc64:C379B5E111E26B50	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:UfSn2+IVRxtGomVeDGdZpL7mz5I9606	rogid:g1+jqOMmde8phrNI9H7nFlXwjH0559292	intact-crc:15F936FF9ABCFCFD|rigid:puDWn9l6XgDWaTpECixgtQCXIGI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48775	uniprotkb:P40454	intact:EBI-743494|ensembl:ENSP00000444788|ensembl:ENSP00000460086|uniprotkb:A8K053	intact:EBI-25278|uniprotkb:D6VVD4|ensemblfungi:YIL153W	psi-mi:t23o_human(display_long)|uniprotkb:Tryptophan pyrrolase(gene name synonym)|uniprotkb:Tryptophan oxygenase(gene name synonym)|uniprotkb:Tryptamin 2,3-dioxygenase(gene name synonym)|uniprotkb:TDO2(gene name)|psi-mi:TDO2(display_short)|uniprotkb:TDO(gene name synonym)|uniprotkb:Tryptophanase(gene name synonym)	psi-mi:ptpa1_yeast(display_long)|uniprotkb:YIL153W(locus name)|uniprotkb:RRD1(gene name)|psi-mi:RRD1(display_short)|uniprotkb:NCS1(gene name synonym)|uniprotkb:YPA1(gene name synonym)|uniprotkb:Peptidyl-prolyl cis-trans isomerase PTPA-1(gene name synonym)|uniprotkb:Phosphotyrosyl phosphatase activator 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11541497|imex:IM-24995-2017	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000151790(gene)|ensembl:ENSG00000262635(gene)|ensembl:ENST00000536354(transcript)|ensembl:ENST00000573403(transcript)|go:"GO:0004833"(tryptophan 2,3-dioxygenase activity)|go:"GO:0005829"(cytosol)|go:"GO:0016597"(amino acid binding)|go:"GO:0019441"(tryptophan catabolic process to kynurenine)|go:"GO:0019442"(tryptophan catabolic process to acetyl-CoA)|go:"GO:0019825"(oxygen binding)|go:"GO:0020037"(heme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051289"(protein homotetramerization)|go:"GO:1904842"(response to nitroglycerin)|interpro:IPR004981(Tryptophan 2,3-dioxygenase)|interpro:IPR037217|mint:P48775|rcsb pdb:4PW8|rcsb pdb:5TI9|rcsb pdb:5TIA|rcsb pdb:6A4I|rcsb pdb:6PYY|rcsb pdb:6PYZ|rcsb pdb:6UD5|rcsb pdb:6VBN|reactome:R-HSA-71240|refseq:NP_005642.1|entrezgene/locuslink:6999(identity)	refseq:NP_012113.1|sgd:S000001415|mint:P40454|dip:DIP-5663N|ensemblfungi:YIL153W(gene)|ensemblfungi:YIL153W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006914"(autophagy)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008160"(protein tyrosine phosphatase activator activity)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0043618"(regulation of transcription from RNA polymerase II promoter in response to stress)|interpro:IPR004327(Phosphotyrosyl phosphatase activator, PTPA)|interpro:IPR037218|interpro:IPR043170|rcsb pdb:2IXO|rcsb pdb:2IXP|sgd:YIL153W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:S+cyc710I52nIFQWgKhXFul9QZw9606	rogid:It2q8WlpmvLEZ1fqpRF5Fypw9Q4559292	intact-crc:6750E32DB99DB85D|rigid:t7CR6F0wQMIWVXG7RAozbNhJ+N0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40454	uniprotkb:P38432	intact:EBI-25278|uniprotkb:D6VVD4|ensemblfungi:YIL153W	intact:EBI-945751|uniprotkb:B2R931|ensembl:ENSP00000240316	psi-mi:ptpa1_yeast(display_long)|uniprotkb:YIL153W(locus name)|uniprotkb:RRD1(gene name)|psi-mi:RRD1(display_short)|uniprotkb:NCS1(gene name synonym)|uniprotkb:YPA1(gene name synonym)|uniprotkb:Peptidyl-prolyl cis-trans isomerase PTPA-1(gene name synonym)|uniprotkb:Phosphotyrosyl phosphatase activator 1(gene name synonym)	psi-mi:coil_human(display_long)|uniprotkb:COIL(gene name)|psi-mi:COIL(display_short)|uniprotkb:CLN80(gene name synonym)|uniprotkb:p80-coilin(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11541488|imex:IM-24995-2016	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012113.1|sgd:S000001415|mint:P40454|dip:DIP-5663N|ensemblfungi:YIL153W(gene)|ensemblfungi:YIL153W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006914"(autophagy)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008160"(protein tyrosine phosphatase activator activity)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0043618"(regulation of transcription from RNA polymerase II promoter in response to stress)|interpro:IPR004327(Phosphotyrosyl phosphatase activator, PTPA)|interpro:IPR037218|interpro:IPR043170|rcsb pdb:2IXO|rcsb pdb:2IXP|sgd:YIL153W(identity)	refseq:NP_004636.1|dip:DIP-38503N|ensembl:ENSG00000121058(gene)|ensembl:ENST00000240316(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0015030"(Cajal body)|go:"GO:0016020"(membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0030619"(U1 snRNA binding)|go:"GO:0030620"(U2 snRNA binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR024822|interpro:IPR031722|mint:P38432|entrezgene/locuslink:8161(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:It2q8WlpmvLEZ1fqpRF5Fypw9Q4559292	rogid:hd5p6AbyA/GYNEeca99Mdb41qM09606	intact-crc:C4D20761D0F71485|rigid:9BOWBg6pGUDiRMnXq/IwLYKkyEQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P35638	uniprotkb:P40454	intact:EBI-742651|ensembl:ENSP00000340671|ensembl:ENSP00000447188|ensembl:ENSP00000494844|uniprotkb:F8VS99	intact:EBI-25278|uniprotkb:D6VVD4|ensemblfungi:YIL153W	psi-mi:ddit3_human(display_long)|uniprotkb:CHOP10(gene name synonym)|uniprotkb:C/EBP-homologous protein(gene name synonym)|uniprotkb:DDIT3(gene name)|psi-mi:DDIT3(display_short)|uniprotkb:CHOP(gene name synonym)|uniprotkb:GADD153(gene name synonym)|uniprotkb:Growth arrest and DNA damage-inducible protein GADD153(gene name synonym)|uniprotkb:C/EBP-homologous protein 10(gene name synonym)|uniprotkb:C/EBP zeta(gene name synonym)|uniprotkb:CCAAT/enhancer-binding protein homologous protein(gene name synonym)	psi-mi:ptpa1_yeast(display_long)|uniprotkb:YIL153W(locus name)|uniprotkb:RRD1(gene name)|psi-mi:RRD1(display_short)|uniprotkb:NCS1(gene name synonym)|uniprotkb:YPA1(gene name synonym)|uniprotkb:Peptidyl-prolyl cis-trans isomerase PTPA-1(gene name synonym)|uniprotkb:Phosphotyrosyl phosphatase activator 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11541479|imex:IM-24995-2015	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001181986.1|refseq:NP_004074.2|refseq:NP_001181982.1|refseq:NP_001181983.1|refseq:NP_001181984.1|ensembl:ENSG00000175197(gene)|go:"GO:0001955"(blood vessel maturation)|ensembl:ENST00000346473(transcript)|ensembl:ENST00000547303(transcript)|ensembl:ENST00000623876(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003677"(DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032792"(negative regulation of CREB transcription factor activity)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0036488"(CHOP-C/EBP complex)|go:"GO:0036499"(PERK-mediated unfolded protein response)|go:"GO:0036500"(ATF6-mediated unfolded protein response)|go:"GO:0042594"(response to starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0032713"(negative regulation of interleukin-4 production)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006983"(ER overload response)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0007049"(cell cycle)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008140"(cAMP response element binding protein binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0005737"(cytoplasm)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0005770"(late endosome)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032700"(negative regulation of interleukin-17 production)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0072655"(establishment of protein localization to mitochondrion)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0140416"(transcription regulator inhibitor activity)|go:"GO:1902237"(positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903026"(negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990442"(intrinsic apoptotic signaling pathway in response to nitrosative stress)|go:"GO:1990617"(CHOP-ATF4 complex)|go:"GO:1990622"(CHOP-ATF3 complex)|go:"GO:2000016"(negative regulation of determination of dorsal identity)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR016670(DNA damage-inducible transcript 3)|mint:P35638|reactome:R-HSA-380994|reactome:R-HSA-381183|reactome:R-HSA-9614657|reactome:R-HSA-9633012|reactome:R-HSA-9648895|go:"GO:0043618"(regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045662"(negative regulation of myoblast differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|dip:DIP-41589N|entrezgene/locuslink:1649(identity)	refseq:NP_012113.1|sgd:S000001415|mint:P40454|dip:DIP-5663N|ensemblfungi:YIL153W(gene)|ensemblfungi:YIL153W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006914"(autophagy)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008160"(protein tyrosine phosphatase activator activity)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0043618"(regulation of transcription from RNA polymerase II promoter in response to stress)|interpro:IPR004327(Phosphotyrosyl phosphatase activator, PTPA)|interpro:IPR037218|interpro:IPR043170|rcsb pdb:2IXO|rcsb pdb:2IXP|sgd:YIL153W(identity)	-	crc64:31905293FB1FBBE2	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:xyMsMwPwid+S2IYb3H0K0pnUc309606	rogid:It2q8WlpmvLEZ1fqpRF5Fypw9Q4559292	intact-crc:A657F87091FC9941|rigid:Jatb23/ICmSYg9k66GVVJQSkuTs	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40454	uniprotkb:P19012	intact:EBI-25278|uniprotkb:D6VVD4|ensemblfungi:YIL153W	intact:EBI-739566|uniprotkb:Q53XV8|uniprotkb:Q9BUG4|uniprotkb:B3KQY1|uniprotkb:B3KRA2|uniprotkb:E0CX14|ensembl:ENSP00000254043|ensembl:ENSP00000377546	psi-mi:ptpa1_yeast(display_long)|uniprotkb:YIL153W(locus name)|uniprotkb:RRD1(gene name)|psi-mi:RRD1(display_short)|uniprotkb:NCS1(gene name synonym)|uniprotkb:YPA1(gene name synonym)|uniprotkb:Peptidyl-prolyl cis-trans isomerase PTPA-1(gene name synonym)|uniprotkb:Phosphotyrosyl phosphatase activator 1(gene name synonym)	psi-mi:k1c15_human(display_long)|uniprotkb:KRT15(gene name)|psi-mi:KRT15(display_short)|uniprotkb:KRTB(gene name synonym)|uniprotkb:Cytokeratin-15(gene name synonym)|uniprotkb:Keratin-15(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11541470|imex:IM-24995-2014	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012113.1|sgd:S000001415|mint:P40454|dip:DIP-5663N|ensemblfungi:YIL153W(gene)|ensemblfungi:YIL153W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006914"(autophagy)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008160"(protein tyrosine phosphatase activator activity)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0043618"(regulation of transcription from RNA polymerase II promoter in response to stress)|interpro:IPR004327(Phosphotyrosyl phosphatase activator, PTPA)|interpro:IPR037218|interpro:IPR043170|rcsb pdb:2IXO|rcsb pdb:2IXP|sgd:YIL153W(identity)	refseq:NP_002266.2|ensembl:ENSG00000171346(gene)|ensembl:ENST00000254043(transcript)|ensembl:ENST00000393976(transcript)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0008544"(epidermis development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097110"(scaffold protein binding)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR039008|mint:P19012|reactome:R-HSA-6805567|reactome:R-HSA-6809371|entrezgene/locuslink:3866(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:It2q8WlpmvLEZ1fqpRF5Fypw9Q4559292	rogid:WrZQBYQvrWcfrR5ojWXrXp6spPE9606	intact-crc:C8BFDC9A8B06764D|rigid:aA/Wb4gvWPLiwm3Mr6RMszphK/8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40454	uniprotkb:P15531	intact:EBI-25278|uniprotkb:D6VVD4|ensemblfungi:YIL153W	intact:EBI-741141|ensembl:ENSP00000376892|uniprotkb:Q6FGK3|uniprotkb:Q86XQ2|uniprotkb:Q9UDJ6	psi-mi:ptpa1_yeast(display_long)|uniprotkb:YIL153W(locus name)|uniprotkb:RRD1(gene name)|psi-mi:RRD1(display_short)|uniprotkb:NCS1(gene name synonym)|uniprotkb:YPA1(gene name synonym)|uniprotkb:Peptidyl-prolyl cis-trans isomerase PTPA-1(gene name synonym)|uniprotkb:Phosphotyrosyl phosphatase activator 1(gene name synonym)	psi-mi:ndka_human(display_long)|uniprotkb:Tumor metastatic process-associated protein(gene name synonym)|uniprotkb:Metastasis inhibition factor nm23(gene name synonym)|uniprotkb:Granzyme A-activated DNase(gene name synonym)|uniprotkb:NME1(gene name)|psi-mi:NME1(display_short)|uniprotkb:NDPKA(gene name synonym)|uniprotkb:NM23(gene name synonym)|uniprotkb:NM23-H1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11541461|imex:IM-24995-2013	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012113.1|sgd:S000001415|mint:P40454|dip:DIP-5663N|ensemblfungi:YIL153W(gene)|ensemblfungi:YIL153W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006914"(autophagy)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008160"(protein tyrosine phosphatase activator activity)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0043618"(regulation of transcription from RNA polymerase II promoter in response to stress)|interpro:IPR004327(Phosphotyrosyl phosphatase activator, PTPA)|interpro:IPR037218|interpro:IPR043170|rcsb pdb:2IXO|rcsb pdb:2IXP|sgd:YIL153W(identity)	refseq:NP_000260.1|refseq:NP_937818.1|ensembl:ENSG00000239672(gene)|ensembl:ENST00000393196(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0002762"(negative regulation of myeloid leukocyte differentiation)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004536"(deoxyribonuclease activity)|go:"GO:0004550"(nucleoside diphosphate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0006183"(GTP biosynthetic process)|go:"GO:0006228"(UTP biosynthetic process)|go:"GO:0006241"(CTP biosynthetic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007595"(lactation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014075"(response to amine)|go:"GO:0016020"(membrane)|go:"GO:0019215"(intermediate filament binding)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051591"(response to cAMP)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071398"(cellular response to fatty acid)|interpro:IPR001564(Nucleoside diphosphate kinase, core)|go:"GO:0019899"(enzyme binding)|interpro:IPR023005|go:"GO:0021766"(hippocampus development)|interpro:IPR034907|interpro:IPR036850|mint:P15531|go:"GO:0030154"(cell differentiation)|go:"GO:0032587"(ruffle membrane)|rcsb pdb:1JXV|rcsb pdb:1UCN|go:"GO:0033574"(response to testosterone)|go:"GO:0035690"|rcsb pdb:2HVD|rcsb pdb:2HVE|rcsb pdb:3L7U|rcsb pdb:4ENO|rcsb pdb:5UI4|reactome:R-HSA-499943|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043024"(ribosomal small subunit binding)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|dip:DIP-39164N|entrezgene/locuslink:4830(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:It2q8WlpmvLEZ1fqpRF5Fypw9Q4559292	rogid:Ut4gK1Xq786CaZzvqdS1eiU5op89606	intact-crc:2530F5D7D52021F4|rigid:kIJctXvQmDZgb6/CHGf4titKCK0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40454	uniprotkb:P14373	intact:EBI-25278|uniprotkb:D6VVD4|ensemblfungi:YIL153W	intact:EBI-719493|uniprotkb:A2BE15|uniprotkb:Q5RJA8|uniprotkb:Q5ST26|uniprotkb:Q6LA73|uniprotkb:Q6NXR9|uniprotkb:Q9BZY6|uniprotkb:Q9UJL3|ensembl:ENSP00000383555|ensembl:ENSP00000392787|ensembl:ENSP00000405229|ensembl:ENSP00000414793|ensembl:ENSP00000366404	psi-mi:ptpa1_yeast(display_long)|uniprotkb:YIL153W(locus name)|uniprotkb:RRD1(gene name)|psi-mi:RRD1(display_short)|uniprotkb:NCS1(gene name synonym)|uniprotkb:YPA1(gene name synonym)|uniprotkb:Peptidyl-prolyl cis-trans isomerase PTPA-1(gene name synonym)|uniprotkb:Phosphotyrosyl phosphatase activator 1(gene name synonym)	psi-mi:tri27_human(display_long)|uniprotkb:TRIM27(gene name)|psi-mi:TRIM27(display_short)|uniprotkb:RNF76(gene name synonym)|uniprotkb:RFP(gene name synonym)|uniprotkb:Ret finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 27(gene name synonym)|uniprotkb:RING finger protein 76(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM27(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11541452|imex:IM-24995-2012	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012113.1|sgd:S000001415|mint:P40454|dip:DIP-5663N|ensemblfungi:YIL153W(gene)|ensemblfungi:YIL153W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006914"(autophagy)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008160"(protein tyrosine phosphatase activator activity)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0043618"(regulation of transcription from RNA polymerase II promoter in response to stress)|interpro:IPR004327(Phosphotyrosyl phosphatase activator, PTPA)|interpro:IPR037218|interpro:IPR043170|rcsb pdb:2IXO|rcsb pdb:2IXP|sgd:YIL153W(identity)	refseq:NP_006501.1|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0090281"(negative regulation of calcium ion import)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR020457|interpro:IPR035791|interpro:IPR043136|mint:P14373|reactome:R-HSA-3232142|reactome:R-HSA-9635465|reactome:R-HSA-8948751|ensembl:ENSG00000204713(gene)|ensembl:ENSG00000215641(gene)|ensembl:ENSG00000229006(gene)|ensembl:ENSG00000234495(gene)|ensembl:ENSG00000237071(gene)|ensembl:ENST00000377199(transcript)|ensembl:ENST00000400720(transcript)|ensembl:ENST00000431123(transcript)|ensembl:ENST00000435528(transcript)|ensembl:ENST00000437160(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001650"(fibrillar center)|go:"GO:0002820"(negative regulation of adaptive immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|entrezgene/locuslink:5987(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:It2q8WlpmvLEZ1fqpRF5Fypw9Q4559292	rogid:dsfH5OUghD8KSaTz1SFw9OYVTK49606	intact-crc:803511C92F855BC1|rigid:FT90KDDa2w97Bz5XrnlMMA3S8so	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O96006	uniprotkb:P40454	intact:EBI-740037|uniprotkb:Q96BY4|ensembl:ENSP00000370616|ensembl:ENSP00000370620|ensembl:ENSP00000370621|ensembl:ENSP00000498725	intact:EBI-25278|uniprotkb:D6VVD4|ensemblfungi:YIL153W	psi-mi:zbed1_human(display_long)|uniprotkb:ZBED1(gene name)|psi-mi:ZBED1(display_short)|uniprotkb:ALTE(gene name synonym)|uniprotkb:DREF(gene name synonym)|uniprotkb:KIAA0785(gene name synonym)|uniprotkb:TRAMP(gene name synonym)|uniprotkb:dREF homolog(gene name synonym)|uniprotkb:Putative Ac-like transposable element(gene name synonym)|uniprotkb:DNA replication-related element-binding factor(gene name synonym)|uniprotkb:Zinc finger BED domain-containing protein 1(gene name synonym)|uniprotkb:hDREF(gene name synonym)	psi-mi:ptpa1_yeast(display_long)|uniprotkb:YIL153W(locus name)|uniprotkb:RRD1(gene name)|psi-mi:RRD1(display_short)|uniprotkb:NCS1(gene name synonym)|uniprotkb:YPA1(gene name synonym)|uniprotkb:Peptidyl-prolyl cis-trans isomerase PTPA-1(gene name synonym)|uniprotkb:Phosphotyrosyl phosphatase activator 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11541443|imex:IM-24995-2011	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164606.1|refseq:NP_001164607.1|refseq:NP_004720.1|ensembl:ENSG00000214717(gene)|ensembl:ENST00000381218(transcript)|ensembl:ENST00000381222(transcript)|ensembl:ENST00000381223(transcript)|ensembl:ENST00000652001(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0031965"(nuclear membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044828"(negative regulation by host of viral genome replication)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0061665"(SUMO ligase activity)|go:"GO:1990466"(protein autosumoylation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003656(Zinc finger, BED-type predicted)|interpro:IPR008906(HAT dimerisation)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR036236|mint:O96006|rcsb pdb:2CT5|reactome:R-HSA-4551638|go:"GO:0005813"(centrosome)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016605"(PML body)|entrezgene/locuslink:9189(identity)	refseq:NP_012113.1|sgd:S000001415|mint:P40454|dip:DIP-5663N|ensemblfungi:YIL153W(gene)|ensemblfungi:YIL153W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006914"(autophagy)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008160"(protein tyrosine phosphatase activator activity)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0043618"(regulation of transcription from RNA polymerase II promoter in response to stress)|interpro:IPR004327(Phosphotyrosyl phosphatase activator, PTPA)|interpro:IPR037218|interpro:IPR043170|rcsb pdb:2IXO|rcsb pdb:2IXP|sgd:YIL153W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:jl97ZV2Kz5YAmQKktWt/wk7OkRw9606	rogid:It2q8WlpmvLEZ1fqpRF5Fypw9Q4559292	intact-crc:7D346E46D2225CAF|rigid:ZLGqKYVB2VfqEsWkHOH+FzojGYI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40454	uniprotkb:Q96MT8-3	intact:EBI-25278|uniprotkb:D6VVD4|ensemblfungi:YIL153W	intact:EBI-11522539|ensembl:ENSP00000507703|ensembl:ENSP00000328382|ensembl:ENSP00000506728|ensembl:ENSP00000506791|ensembl:ENSP00000506828|ensembl:ENSP00000507228	psi-mi:ptpa1_yeast(display_long)|uniprotkb:YIL153W(locus name)|uniprotkb:RRD1(gene name)|psi-mi:RRD1(display_short)|uniprotkb:NCS1(gene name synonym)|uniprotkb:YPA1(gene name synonym)|uniprotkb:Peptidyl-prolyl cis-trans isomerase PTPA-1(gene name synonym)|uniprotkb:Phosphotyrosyl phosphatase activator 1(gene name synonym)	psi-mi:q96mt8-3(display_long)|uniprotkb:CEP63(gene name)|psi-mi:CEP63(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11541589|imex:IM-24995-2027	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012113.1|sgd:S000001415|mint:P40454|dip:DIP-5663N|ensemblfungi:YIL153W(gene)|ensemblfungi:YIL153W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006914"(autophagy)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008160"(protein tyrosine phosphatase activator activity)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0043618"(regulation of transcription from RNA polymerase II promoter in response to stress)|interpro:IPR004327(Phosphotyrosyl phosphatase activator, PTPA)|interpro:IPR037218|interpro:IPR043170|rcsb pdb:2IXO|rcsb pdb:2IXP|sgd:YIL153W(identity)	intact:EBI-741977(isoform-parent)|ensembl:ENST00000332047(transcript)|ensembl:ENST00000682042(transcript)|ensembl:ENST00000682800(transcript)|ensembl:ENST00000682858(transcript)|ensembl:ENST00000683177(transcript)|ensembl:ENST00000683861(transcript)|ensembl:ENSG00000182923(gene)|uniprotkb:Q96MT8-3(isoform-parent)|entrezgene/locuslink:80254(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:It2q8WlpmvLEZ1fqpRF5Fypw9Q4559292	rogid:U0uvVcOCzA8Qp2cCB0ilixgd4Yc9606	intact-crc:5770DB558DBE9374|rigid:Ql13sIEA35Z0th8Tdvq89H0re2s	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96GX9	uniprotkb:P40454	intact:EBI-359248|ensembl:ENSP00000379133|intact:EBI-2848621|uniprotkb:Q6PJX6|uniprotkb:Q8WVU2|uniprotkb:Q96HK2|uniprotkb:Q9Y318|uniprotkb:A8K9D3	intact:EBI-25278|uniprotkb:D6VVD4|ensemblfungi:YIL153W	psi-mi:mtnb_human(display_long)|uniprotkb:APIP(gene name)|psi-mi:APIP(display_short)|uniprotkb:CGI-29(orf name)|uniprotkb:APAF1-interacting protein(gene name synonym)	psi-mi:ptpa1_yeast(display_long)|uniprotkb:YIL153W(locus name)|uniprotkb:RRD1(gene name)|psi-mi:RRD1(display_short)|uniprotkb:NCS1(gene name synonym)|uniprotkb:YPA1(gene name synonym)|uniprotkb:Peptidyl-prolyl cis-trans isomerase PTPA-1(gene name synonym)|uniprotkb:Phosphotyrosyl phosphatase activator 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11541580|imex:IM-24995-2026	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000149089(gene)|ensembl:ENST00000395787(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019284"(L-methionine salvage from S-adenosylmethionine)|go:"GO:0019509"(L-methionine salvage from methylthioadenosine)|refseq:NP_057041.2|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0046570"(methylthioribulose 1-phosphate dehydratase activity)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0070269"(pyroptosis)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|interpro:IPR001303(Class II aldolase/adducin, N-terminal)|interpro:IPR017714(Methylthioribulose-1-phosphate dehydratase)|interpro:IPR027514|interpro:IPR036409|rcsb pdb:4M6R|reactome:R-HSA-111458|reactome:R-HSA-1237112|reactome:R-HSA-9627069|entrezgene/locuslink:51074(identity)	refseq:NP_012113.1|sgd:S000001415|mint:P40454|dip:DIP-5663N|ensemblfungi:YIL153W(gene)|ensemblfungi:YIL153W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006914"(autophagy)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008160"(protein tyrosine phosphatase activator activity)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0043618"(regulation of transcription from RNA polymerase II promoter in response to stress)|interpro:IPR004327(Phosphotyrosyl phosphatase activator, PTPA)|interpro:IPR037218|interpro:IPR043170|rcsb pdb:2IXO|rcsb pdb:2IXP|sgd:YIL153W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:k+IcLEB6jPgZW0Zl597PZyGbHH49606	rogid:It2q8WlpmvLEZ1fqpRF5Fypw9Q4559292	intact-crc:E177D2901399226E|rigid:HYMUYXyFDqqwnxfs/MAmVdVHFVU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96CV9-2	uniprotkb:P40454	intact:EBI-9091423|ensembl:ENSP00000368027|ensembl:ENSP00000368040	intact:EBI-25278|uniprotkb:D6VVD4|ensemblfungi:YIL153W	psi-mi:q96cv9-2(display_long)|uniprotkb:E3-14.7K-interacting protein(gene name synonym)|uniprotkb:FIP-2(gene name synonym)|uniprotkb:FIP2(gene name synonym)|uniprotkb:GLC1E(gene name synonym)|uniprotkb:HIP7(gene name synonym)|uniprotkb:HYPL(gene name synonym)|uniprotkb:Huntingtin yeast partner L(gene name synonym)|uniprotkb:Huntingtin-interacting protein 7(gene name synonym)|uniprotkb:Huntingtin-interacting protein L(gene name synonym)|uniprotkb:NEMO-related protein(gene name synonym)|uniprotkb:NRP(gene name synonym)|uniprotkb:Optic neuropathy-inducing protein(gene name synonym)|uniprotkb:Transcription factor IIIA-interacting protein(gene name synonym)|uniprotkb:OPTN(gene name)|psi-mi:OPTN(display_short)	psi-mi:ptpa1_yeast(display_long)|uniprotkb:YIL153W(locus name)|uniprotkb:RRD1(gene name)|psi-mi:RRD1(display_short)|uniprotkb:NCS1(gene name synonym)|uniprotkb:YPA1(gene name synonym)|uniprotkb:Peptidyl-prolyl cis-trans isomerase PTPA-1(gene name synonym)|uniprotkb:Phosphotyrosyl phosphatase activator 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11541571|imex:IM-24995-2025	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-748974(isoform-parent)|ensembl:ENST00000378752(transcript)|ensembl:ENST00000378764(transcript)|ensembl:ENSG00000123240(gene)|uniprotkb:Q96CV9-2(isoform-parent)|entrezgene/locuslink:10133(identity)	refseq:NP_012113.1|sgd:S000001415|mint:P40454|dip:DIP-5663N|ensemblfungi:YIL153W(gene)|ensemblfungi:YIL153W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006914"(autophagy)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008160"(protein tyrosine phosphatase activator activity)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0043618"(regulation of transcription from RNA polymerase II promoter in response to stress)|interpro:IPR004327(Phosphotyrosyl phosphatase activator, PTPA)|interpro:IPR037218|interpro:IPR043170|rcsb pdb:2IXO|rcsb pdb:2IXP|sgd:YIL153W(identity)	-	isoform-comment:No experimental confirmation available.	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2018/04/06	rogid:ygzEQkiDJwDAMUuFQuOWsSIqwAk9606	rogid:It2q8WlpmvLEZ1fqpRF5Fypw9Q4559292	intact-crc:A24FD9BCF09A8BA8|rigid:Bmag+6huo34L9cXAp9+ovi4Xffs	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96CV9	uniprotkb:P40454	intact:EBI-748974|uniprotkb:Q5T672|uniprotkb:Q5T673|uniprotkb:Q5T674|uniprotkb:Q5T675|uniprotkb:Q7LDL9|uniprotkb:Q8N562|uniprotkb:Q9UET9|uniprotkb:Q9UEV4|uniprotkb:Q9Y218|uniprotkb:B3KP00|uniprotkb:D3DRS4|uniprotkb:D3DRS8|ensembl:ENSP00000263036|ensembl:ENSP00000368021|ensembl:ENSP00000368022|ensembl:ENSP00000368032	intact:EBI-25278|uniprotkb:D6VVD4|ensemblfungi:YIL153W	psi-mi:optn_human(display_long)|uniprotkb:HYPL(gene name synonym)|uniprotkb:Optic neuropathy-inducing protein(gene name synonym)|uniprotkb:E3-14.7K-interacting protein(gene name synonym)|uniprotkb:FIP-2(gene name synonym)|uniprotkb:Huntingtin-interacting protein L(gene name synonym)|uniprotkb:Huntingtin yeast partner L(gene name synonym)|uniprotkb:NEMO-related protein(gene name synonym)|uniprotkb:Transcription factor IIIA-interacting protein(gene name synonym)|uniprotkb:OPTN(gene name)|psi-mi:OPTN(display_short)|uniprotkb:FIP2(gene name synonym)|uniprotkb:GLC1E(gene name synonym)|uniprotkb:NRP(gene name synonym)|uniprotkb:HIP7(gene name synonym)|uniprotkb:Huntingtin-interacting protein 7(gene name synonym)	psi-mi:ptpa1_yeast(display_long)|uniprotkb:YIL153W(locus name)|uniprotkb:RRD1(gene name)|psi-mi:RRD1(display_short)|uniprotkb:NCS1(gene name synonym)|uniprotkb:YPA1(gene name synonym)|uniprotkb:Peptidyl-prolyl cis-trans isomerase PTPA-1(gene name synonym)|uniprotkb:Phosphotyrosyl phosphatase activator 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11541562|imex:IM-24995-2024	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001008212.1|refseq:NP_001008213.1|refseq:NP_001008214.1|refseq:NP_068815.2|ensembl:ENSG00000123240(gene)|ensembl:ENST00000263036(transcript)|ensembl:ENST00000378747(transcript)|ensembl:ENST00000378748(transcript)|ensembl:ENST00000378757(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001920"(negative regulation of receptor recycling)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0007030"(Golgi organization)|go:"GO:0007165"(signal transduction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008219"(cell death)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0061734"(parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:1904417"(positive regulation of xenophagy)|interpro:IPR021063|interpro:IPR032419|interpro:IPR032939|interpro:IPR034735|mint:Q96CV9|rcsb pdb:2LO4|rcsb pdb:2LUE|rcsb pdb:3VTV|rcsb pdb:3VTW|rcsb pdb:5AAZ|rcsb pdb:5B83|rcsb pdb:5EOA|rcsb pdb:5EOF|rcsb pdb:7CZM|reactome:R-HSA-2565942|reactome:R-HSA-8854214|dip:DIP-42001N|entrezgene/locuslink:10133(identity)	refseq:NP_012113.1|sgd:S000001415|mint:P40454|dip:DIP-5663N|ensemblfungi:YIL153W(gene)|ensemblfungi:YIL153W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006914"(autophagy)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008160"(protein tyrosine phosphatase activator activity)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0043618"(regulation of transcription from RNA polymerase II promoter in response to stress)|interpro:IPR004327(Phosphotyrosyl phosphatase activator, PTPA)|interpro:IPR037218|interpro:IPR043170|rcsb pdb:2IXO|rcsb pdb:2IXP|sgd:YIL153W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2018/04/06	rogid:jcCTXDx1bJq3K5mgNUD73jeWeBU9606	rogid:It2q8WlpmvLEZ1fqpRF5Fypw9Q4559292	intact-crc:F708D34E8A0479B4|rigid:qhPMcGgyIW6NDLjpoigBcTOf55k	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40454	uniprotkb:Q8TC20-4	intact:EBI-25278|uniprotkb:D6VVD4|ensemblfungi:YIL153W	intact:EBI-11522698|ensembl:ENSP00000390644	psi-mi:ptpa1_yeast(display_long)|uniprotkb:YIL153W(locus name)|uniprotkb:RRD1(gene name)|psi-mi:RRD1(display_short)|uniprotkb:NCS1(gene name synonym)|uniprotkb:YPA1(gene name synonym)|uniprotkb:Peptidyl-prolyl cis-trans isomerase PTPA-1(gene name synonym)|uniprotkb:Phosphotyrosyl phosphatase activator 1(gene name synonym)	psi-mi:q8tc20-4(display_long)|uniprotkb:CTAG3(gene name synonym)|uniprotkb:Cancer/testis antigen 3(gene name synonym)|uniprotkb:CAGE1(gene name)|psi-mi:CAGE1(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11541553|imex:IM-24995-2023	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012113.1|sgd:S000001415|mint:P40454|dip:DIP-5663N|ensemblfungi:YIL153W(gene)|ensemblfungi:YIL153W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006914"(autophagy)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008160"(protein tyrosine phosphatase activator activity)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0043618"(regulation of transcription from RNA polymerase II promoter in response to stress)|interpro:IPR004327(Phosphotyrosyl phosphatase activator, PTPA)|interpro:IPR037218|interpro:IPR043170|rcsb pdb:2IXO|rcsb pdb:2IXP|sgd:YIL153W(identity)	intact:EBI-10196469(isoform-parent)|ensembl:ENSG00000164304(gene)|ensembl:ENST00000458291(transcript)|uniprotkb:Q8TC20-4(isoform-parent)|entrezgene/locuslink:285782(identity)	-	-	isoform-comment:No experimental confirmation available. May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:It2q8WlpmvLEZ1fqpRF5Fypw9Q4559292	rogid:rbycl1bawuMuBA8D5NfrekzCADM9606	intact-crc:4815E1336B7AFD32|rigid:13PoisQfPDKOkC2l9hFj6Oh7Dzw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40454	uniprotkb:Q8NHQ1	intact:EBI-25278|uniprotkb:D6VVD4|ensemblfungi:YIL153W	intact:EBI-739624|ensembl:ENSP00000264982|ensembl:ENSP00000419231|uniprotkb:Q96B31|uniprotkb:Q9H2C3|uniprotkb:Q9H2Z1|uniprotkb:Q9H940|uniprotkb:D3DNE9|uniprotkb:B7Z5I8|uniprotkb:B7Z7E8|uniprotkb:F5GZX8	psi-mi:ptpa1_yeast(display_long)|uniprotkb:YIL153W(locus name)|uniprotkb:RRD1(gene name)|psi-mi:RRD1(display_short)|uniprotkb:NCS1(gene name synonym)|uniprotkb:YPA1(gene name synonym)|uniprotkb:Peptidyl-prolyl cis-trans isomerase PTPA-1(gene name synonym)|uniprotkb:Phosphotyrosyl phosphatase activator 1(gene name synonym)	psi-mi:cep70_human(display_long)|uniprotkb:CEP70(gene name)|psi-mi:CEP70(display_short)|uniprotkb:BITE(gene name synonym)|uniprotkb:p10-binding protein(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11541544|imex:IM-24995-2022	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012113.1|sgd:S000001415|mint:P40454|dip:DIP-5663N|ensemblfungi:YIL153W(gene)|ensemblfungi:YIL153W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006914"(autophagy)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008160"(protein tyrosine phosphatase activator activity)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0043618"(regulation of transcription from RNA polymerase II promoter in response to stress)|interpro:IPR004327(Phosphotyrosyl phosphatase activator, PTPA)|interpro:IPR037218|interpro:IPR043170|rcsb pdb:2IXO|rcsb pdb:2IXP|sgd:YIL153W(identity)	ensembl:ENSG00000114107(gene)|ensembl:ENST00000264982(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|interpro:IPR019734|interpro:IPR037692|mint:Q8NHQ1|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|ensembl:ENST00000484888(transcript)|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_077817.2|refseq:XP_016862764.1|refseq:NP_001275893.1|refseq:NP_001275894.1|refseq:NP_001275895.1|refseq:NP_001275896.1|refseq:NP_001307527.1|refseq:NP_001307529.1|entrezgene/locuslink:80321(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:It2q8WlpmvLEZ1fqpRF5Fypw9Q4559292	rogid:S4yveQWcvdVtAUX65gqrJ5Dv0Mc9606	intact-crc:CBEDDEB58189A38C|rigid:xt0sTaF6qMCpURJuIBUzQiFieOM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8NA61-2	uniprotkb:P40454	intact:EBI-11524851|ensembl:ENSP00000368249|ensembl:ENSP00000480148	intact:EBI-25278|uniprotkb:D6VVD4|ensemblfungi:YIL153W	psi-mi:q8na61-2(display_long)|uniprotkb:CBY2(gene name)|psi-mi:CBY2(display_short)|uniprotkb:SPERT(gene name synonym)|uniprotkb:Spermatid-associated protein(gene name synonym)	psi-mi:ptpa1_yeast(display_long)|uniprotkb:YIL153W(locus name)|uniprotkb:RRD1(gene name)|psi-mi:RRD1(display_short)|uniprotkb:NCS1(gene name synonym)|uniprotkb:YPA1(gene name synonym)|uniprotkb:Peptidyl-prolyl cis-trans isomerase PTPA-1(gene name synonym)|uniprotkb:Phosphotyrosyl phosphatase activator 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11541535|imex:IM-24995-2021	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-741724(isoform-parent)|ensembl:ENSG00000174015(gene)|ensembl:ENST00000378966(transcript)|ensembl:ENST00000610924(transcript)|uniprotkb:Q8NA61-2(isoform-parent)|entrezgene/locuslink:220082(identity)	refseq:NP_012113.1|sgd:S000001415|mint:P40454|dip:DIP-5663N|ensemblfungi:YIL153W(gene)|ensemblfungi:YIL153W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006914"(autophagy)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008160"(protein tyrosine phosphatase activator activity)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0043618"(regulation of transcription from RNA polymerase II promoter in response to stress)|interpro:IPR004327(Phosphotyrosyl phosphatase activator, PTPA)|interpro:IPR037218|interpro:IPR043170|rcsb pdb:2IXO|rcsb pdb:2IXP|sgd:YIL153W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:SogYcXGGMYRYzB9xKC5o0pEtsDs9606	rogid:It2q8WlpmvLEZ1fqpRF5Fypw9Q4559292	intact-crc:78A05C54E4674480|rigid:bQV0FaOfr/y8MZEI89atVwxZAjI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40454	uniprotkb:Q8N7W2-2	intact:EBI-25278|uniprotkb:D6VVD4|ensemblfungi:YIL153W	intact:EBI-10181188|ensembl:ENSP00000367868	psi-mi:ptpa1_yeast(display_long)|uniprotkb:YIL153W(locus name)|uniprotkb:RRD1(gene name)|psi-mi:RRD1(display_short)|uniprotkb:NCS1(gene name synonym)|uniprotkb:YPA1(gene name synonym)|uniprotkb:Peptidyl-prolyl cis-trans isomerase PTPA-1(gene name synonym)|uniprotkb:Phosphotyrosyl phosphatase activator 1(gene name synonym)	psi-mi:q8n7w2-2(display_long)|uniprotkb:C10orf30(gene name synonym)|uniprotkb:BEND7(gene name)|psi-mi:BEND7(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11541524|imex:IM-24995-2020	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012113.1|sgd:S000001415|mint:P40454|dip:DIP-5663N|ensemblfungi:YIL153W(gene)|ensemblfungi:YIL153W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006914"(autophagy)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008160"(protein tyrosine phosphatase activator activity)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0043618"(regulation of transcription from RNA polymerase II promoter in response to stress)|interpro:IPR004327(Phosphotyrosyl phosphatase activator, PTPA)|interpro:IPR037218|interpro:IPR043170|rcsb pdb:2IXO|rcsb pdb:2IXP|sgd:YIL153W(identity)	ensembl:ENSG00000165626(gene)|ensembl:ENST00000378605(transcript)|intact:EBI-743382(isoform-parent)|uniprotkb:Q8N7W2-2(isoform-parent)|entrezgene/locuslink:222389(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:It2q8WlpmvLEZ1fqpRF5Fypw9Q4559292	rogid:p6qrTn80hLyVU0W2Tvwn50Q4m5I9606	intact-crc:EA7BFF4E142AC7F4|rigid:8uzaz0eS8i/AV8eTSZYTcOFuBWY	false	-	sufficient binding region:10-374	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q5JR59-3	uniprotkb:P40454	intact:EBI-11522433|ensembl:ENSP00000370186	intact:EBI-25278|uniprotkb:D6VVD4|ensemblfungi:YIL153W	psi-mi:q5jr59-3(display_long)|uniprotkb:MTUS2(gene name)|psi-mi:MTUS2(display_short)|uniprotkb:CAZIP(gene name synonym)|uniprotkb:Cardiac zipper protein(gene name synonym)|uniprotkb:KIAA0774(gene name synonym)|uniprotkb:Microtubule plus-end tracking protein TIP150(gene name synonym)|uniprotkb:TIP150(gene name synonym)	psi-mi:ptpa1_yeast(display_long)|uniprotkb:YIL153W(locus name)|uniprotkb:RRD1(gene name)|psi-mi:RRD1(display_short)|uniprotkb:NCS1(gene name synonym)|uniprotkb:YPA1(gene name synonym)|uniprotkb:Peptidyl-prolyl cis-trans isomerase PTPA-1(gene name synonym)|uniprotkb:Phosphotyrosyl phosphatase activator 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11541515|imex:IM-24995-2019	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000132938(gene)|ensembl:ENST00000380808(transcript)|intact:EBI-742948(isoform-parent)|uniprotkb:Q5JR59-3(isoform-parent)|entrezgene/locuslink:23281(identity)	refseq:NP_012113.1|sgd:S000001415|mint:P40454|dip:DIP-5663N|ensemblfungi:YIL153W(gene)|ensemblfungi:YIL153W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006914"(autophagy)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008160"(protein tyrosine phosphatase activator activity)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0043618"(regulation of transcription from RNA polymerase II promoter in response to stress)|interpro:IPR004327(Phosphotyrosyl phosphatase activator, PTPA)|interpro:IPR037218|interpro:IPR043170|rcsb pdb:2IXO|rcsb pdb:2IXP|sgd:YIL153W(identity)	-	isoform-comment:No experimental confirmation available.	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:npId9tC7VoLN/jteoBiRbSYChPs9606	rogid:It2q8WlpmvLEZ1fqpRF5Fypw9Q4559292	intact-crc:FEC891BE572DE5AB|rigid:63HnY7CBz4Rqs48lh7DgOXN3Gxw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P81877	uniprotkb:P40454	intact:EBI-748077|uniprotkb:Q8N2Q2|uniprotkb:Q9BWW6|uniprotkb:Q9Y4T7|uniprotkb:B7Z2L9|uniprotkb:E9PDA8|uniprotkb:B2R5W1|uniprotkb:B7Z1J2|uniprotkb:B7Z665|uniprotkb:D6RH18|uniprotkb:E9PB74|intact:EBI-28967061|ensembl:ENSP00000322977	intact:EBI-25278|uniprotkb:D6VVD4|ensemblfungi:YIL153W	psi-mi:ssbp2_human(display_long)|uniprotkb:Sequence-specific single-stranded-DNA-binding protein 2(gene name synonym)|uniprotkb:SSBP2(gene name)|psi-mi:SSBP2(display_short)|uniprotkb:SSDP2(gene name synonym)	psi-mi:ptpa1_yeast(display_long)|uniprotkb:YIL153W(locus name)|uniprotkb:RRD1(gene name)|psi-mi:RRD1(display_short)|uniprotkb:NCS1(gene name synonym)|uniprotkb:YPA1(gene name synonym)|uniprotkb:Peptidyl-prolyl cis-trans isomerase PTPA-1(gene name synonym)|uniprotkb:Phosphotyrosyl phosphatase activator 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11541506|imex:IM-24995-2018	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000322977|ensembl:ENST00000505980|ensembl:ENSP00000423969|ensembl:ENST00000509053|ensembl:ENSP00000422961|ensembl:ENST00000514493|ensembl:ENSP00000426183|ensembl:ENST00000515395|ensembl:ENSP00000424657|refseq:NP_001243661.1|refseq:NP_036578.2|refseq:NP_001243665.1|refseq:NP_001243663.1|refseq:NP_001243664.1|refseq:NP_001243662.1|ensembl:ENSG00000145687(gene)|ensembl:ENST00000320672(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR008116(Sequence-specific single-strand DNA-binding protein)|mint:P81877|rcsb pdb:6IWV|rcsb pdb:6TYD|dip:DIP-29459N|entrezgene/locuslink:23635(identity)	refseq:NP_012113.1|sgd:S000001415|mint:P40454|dip:DIP-5663N|ensemblfungi:YIL153W(gene)|ensemblfungi:YIL153W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006914"(autophagy)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008160"(protein tyrosine phosphatase activator activity)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0043618"(regulation of transcription from RNA polymerase II promoter in response to stress)|interpro:IPR004327(Phosphotyrosyl phosphatase activator, PTPA)|interpro:IPR037218|interpro:IPR043170|rcsb pdb:2IXO|rcsb pdb:2IXP|sgd:YIL153W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:CMmZPTurp1G6Y2q7GP/pTMlFM549606	rogid:It2q8WlpmvLEZ1fqpRF5Fypw9Q4559292	intact-crc:C15828FBDA2B84AE|rigid:GhV/GnLYK6m7wnyOqY+K5wXl64s	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q08379	uniprotkb:P40455	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	intact:EBI-25274|uniprotkb:D6VVD5|ensemblfungi:YIL152W	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:yip2_yeast(display_long)|uniprotkb:YIL152W(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11541674|imex:IM-24995-2036	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N|entrezgene/locuslink:2801(identity)	sgd:S000001414|refseq:NP_012114.1|mint:P40455|dip:DIP-2047N|ensemblfungi:YIL152W(gene)|ensemblfungi:YIL152W_mRNA(transcript)|sgd:YIL152W(identity)	-	-	crc64:07550E3F491F53A8	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2017/05/26	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	rogid:t5hCm1ck6kpFUxpEd8CsyLrHbEw559292	intact-crc:E5DEB66FF92B407D|rigid:X+W6oH3jCPQgWHpfShH+ReGKEHU	false	sufficient binding region:383-1002	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40454	uniprotkb:Q9Y3Q8	intact:EBI-25278|uniprotkb:D6VVD4|ensemblfungi:YIL153W	intact:EBI-739485|uniprotkb:A8MWR6|ensembl:ENSP00000300181|uniprotkb:A4D2C3|uniprotkb:D6W5V9	psi-mi:ptpa1_yeast(display_long)|uniprotkb:YIL153W(locus name)|uniprotkb:RRD1(gene name)|psi-mi:RRD1(display_short)|uniprotkb:NCS1(gene name synonym)|uniprotkb:YPA1(gene name synonym)|uniprotkb:Peptidyl-prolyl cis-trans isomerase PTPA-1(gene name synonym)|uniprotkb:Phosphotyrosyl phosphatase activator 1(gene name synonym)	psi-mi:t22d4_human(display_long)|uniprotkb:TSC22D4(gene name)|psi-mi:TSC22D4(display_short)|uniprotkb:TILZ2(gene name synonym)|uniprotkb:TSC22-related-inducible leucine zipper protein 2(gene name synonym)|uniprotkb:Tsc-22-like protein THG-1(gene name synonym)|uniprotkb:THG1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11541665|imex:IM-24995-2035	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012113.1|sgd:S000001415|mint:P40454|dip:DIP-5663N|ensemblfungi:YIL153W(gene)|ensemblfungi:YIL153W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006914"(autophagy)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008160"(protein tyrosine phosphatase activator activity)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0043618"(regulation of transcription from RNA polymerase II promoter in response to stress)|interpro:IPR004327(Phosphotyrosyl phosphatase activator, PTPA)|interpro:IPR037218|interpro:IPR043170|rcsb pdb:2IXO|rcsb pdb:2IXP|sgd:YIL153W(identity)	ensembl:ENSG00000166925(gene)|ensembl:ENST00000300181(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006970"(response to osmotic stress)|interpro:IPR000580(TSC-22 / Dip / Bun)|interpro:IPR042553|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|refseq:NP_112197.1|refseq:NP_001289972.1|entrezgene/locuslink:81628(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:It2q8WlpmvLEZ1fqpRF5Fypw9Q4559292	rogid:eL12cHY76zEPOXzT1HFKPSckS8Y9606	intact-crc:0058132B0325DBA6|rigid:Z3ZOSQgaqcMkkGs4LrBuRiUQYSc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40454	uniprotkb:Q9Y3A3	intact:EBI-25278|uniprotkb:D6VVD4|ensemblfungi:YIL153W	intact:EBI-713935|uniprotkb:Q7Z4Y6|uniprotkb:Q9H2P3|uniprotkb:Q53SE0|uniprotkb:Q9H5J1|uniprotkb:Q9Y4T8|ensembl:ENSP00000315702|uniprotkb:B4DML0	psi-mi:ptpa1_yeast(display_long)|uniprotkb:YIL153W(locus name)|uniprotkb:RRD1(gene name)|psi-mi:RRD1(display_short)|uniprotkb:NCS1(gene name synonym)|uniprotkb:YPA1(gene name synonym)|uniprotkb:Peptidyl-prolyl cis-trans isomerase PTPA-1(gene name synonym)|uniprotkb:Phosphotyrosyl phosphatase activator 1(gene name synonym)	psi-mi:phocn_human(display_long)|uniprotkb:MOB4(gene name)|psi-mi:MOB4(display_short)|uniprotkb:2C4D(gene name synonym)|uniprotkb:Class II mMOB1(gene name synonym)|uniprotkb:MOB3(gene name synonym)|uniprotkb:MOBKL3(gene name synonym)|uniprotkb:Mob1 homolog 3(gene name synonym)|uniprotkb:Mps one binder kinase activator-like 3(gene name synonym)|uniprotkb:PHOCN(gene name synonym)|uniprotkb:PREI3(gene name synonym)|uniprotkb:Preimplantation protein 3(gene name synonym)|uniprotkb:CGI-95(orf name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11541656|imex:IM-24995-2034	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012113.1|sgd:S000001415|mint:P40454|dip:DIP-5663N|ensemblfungi:YIL153W(gene)|ensemblfungi:YIL153W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006914"(autophagy)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008160"(protein tyrosine phosphatase activator activity)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0043618"(regulation of transcription from RNA polymerase II promoter in response to stress)|interpro:IPR004327(Phosphotyrosyl phosphatase activator, PTPA)|interpro:IPR037218|interpro:IPR043170|rcsb pdb:2IXO|rcsb pdb:2IXP|sgd:YIL153W(identity)	ensembl:ENSG00000115540(gene)|ensembl:ENST00000323303(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR005301(Mob1/phocein)|interpro:IPR036703|mint:Q9Y3A3|rcsb pdb:5YF4|rcsb pdb:7K36|refseq:NP_001094289.1|refseq:NP_001191023.1|refseq:NP_056202.2|refseq:NP_955776.1|entrezgene/locuslink:25843(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:It2q8WlpmvLEZ1fqpRF5Fypw9Q4559292	rogid:ihsb3qrdGqwKdh6ZhHlJlwBGJbc9606	intact-crc:8382D855BC0E55C4|rigid:Cbagm22pvT6WWsyDkpFx9yTzWz4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9Y2J4	uniprotkb:P40454	intact:EBI-746752|intact:EBI-28986657|ensembl:ENSP00000409999|uniprotkb:Q53EP1|uniprotkb:Q96F99|uniprotkb:Q9UKB4|uniprotkb:A8K6F1|uniprotkb:B7Z5Q1|uniprotkb:E9PHW3	intact:EBI-25278|uniprotkb:D6VVD4|ensemblfungi:YIL153W	psi-mi:amol2_human(display_long)|uniprotkb:Leman coiled-coil protein(gene name synonym)|uniprotkb:AMOTL2(gene name)|psi-mi:AMOTL2(display_short)|uniprotkb:KIAA0989(gene name synonym)	psi-mi:ptpa1_yeast(display_long)|uniprotkb:YIL153W(locus name)|uniprotkb:RRD1(gene name)|psi-mi:RRD1(display_short)|uniprotkb:NCS1(gene name synonym)|uniprotkb:YPA1(gene name synonym)|uniprotkb:Peptidyl-prolyl cis-trans isomerase PTPA-1(gene name synonym)|uniprotkb:Phosphotyrosyl phosphatase activator 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11541645|imex:IM-24995-2033	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001265612.1|refseq:NP_001265614.1|ensembl:ENSG00000114019(gene)|refseq:XP_006713717.1|refseq:NP_057285.3|refseq:XP_011511183.1|ensembl:ENST00000422605(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0003365"(establishment of cell polarity involved in ameboidal cell migration)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0035329"(hippo signaling)|go:"GO:0055037"(recycling endosome)|interpro:IPR009114(Angiomotin)|interpro:IPR024646|mint:Q9Y2J4|reactome:R-HSA-2028269|refseq:XP_016862069.1|refseq:XP_016862070.1|refseq:XP_016862071.1|ensembl:ENST00000249883|ensembl:ENSP00000249883|ensembl:ENSP00000409999|ensembl:ENST00000513145|ensembl:ENSP00000425475|ensembl:ENST00000514516|ensembl:ENSP00000424765|dip:DIP-57510N|entrezgene/locuslink:51421(identity)	refseq:NP_012113.1|sgd:S000001415|mint:P40454|dip:DIP-5663N|ensemblfungi:YIL153W(gene)|ensemblfungi:YIL153W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006914"(autophagy)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008160"(protein tyrosine phosphatase activator activity)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0043618"(regulation of transcription from RNA polymerase II promoter in response to stress)|interpro:IPR004327(Phosphotyrosyl phosphatase activator, PTPA)|interpro:IPR037218|interpro:IPR043170|rcsb pdb:2IXO|rcsb pdb:2IXP|sgd:YIL153W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:SHtKAcLLnTpSSLwVE7yQ1WECoZk9606	rogid:It2q8WlpmvLEZ1fqpRF5Fypw9Q4559292	intact-crc:FCF1639FE00E665E|rigid:rgEEfEcCVSwx03CIHbOgbMIWwIs	false	sufficient binding region:314-779	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40454	uniprotkb:Q9UJV3-2	intact:EBI-25278|uniprotkb:D6VVD4|ensemblfungi:YIL153W	intact:EBI-10172526|ensembl:ENSP00000413976	psi-mi:ptpa1_yeast(display_long)|uniprotkb:YIL153W(locus name)|uniprotkb:RRD1(gene name)|psi-mi:RRD1(display_short)|uniprotkb:NCS1(gene name synonym)|uniprotkb:YPA1(gene name synonym)|uniprotkb:Peptidyl-prolyl cis-trans isomerase PTPA-1(gene name synonym)|uniprotkb:Phosphotyrosyl phosphatase activator 1(gene name synonym)	psi-mi:q9ujv3-2(display_long)|uniprotkb:RING-type E3 ubiquitin transferase MID2(gene name synonym)|uniprotkb:FXY2(gene name synonym)|uniprotkb:Midin-2(gene name synonym)|uniprotkb:Midline defect 2(gene name synonym)|uniprotkb:Midline-2(gene name synonym)|uniprotkb:RING finger protein 60(gene name synonym)|uniprotkb:RNF60(gene name synonym)|uniprotkb:TRIM1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 1(gene name synonym)|uniprotkb:MID2(gene name)|psi-mi:MID2(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11541634|imex:IM-24995-2032	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012113.1|sgd:S000001415|mint:P40454|dip:DIP-5663N|ensemblfungi:YIL153W(gene)|ensemblfungi:YIL153W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006914"(autophagy)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008160"(protein tyrosine phosphatase activator activity)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0043618"(regulation of transcription from RNA polymerase II promoter in response to stress)|interpro:IPR004327(Phosphotyrosyl phosphatase activator, PTPA)|interpro:IPR037218|interpro:IPR043170|rcsb pdb:2IXO|rcsb pdb:2IXP|sgd:YIL153W(identity)	intact:EBI-751983(isoform-parent)|uniprotkb:Q9UJV3-2(isoform-parent)|ensembl:ENSG00000080561(gene)|ensembl:ENST00000443968(transcript)|entrezgene/locuslink:11043(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:It2q8WlpmvLEZ1fqpRF5Fypw9Q4559292	rogid:/FJ+V2H7SaWon7caUWkEkmHFVxQ9606	intact-crc:76CC3B53CAC23CD6|rigid:CcpVbbc0xfEqFA2I3Oq4E/m04K8	false	-	sufficient binding region:21-705	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UI14	uniprotkb:P40454	intact:EBI-712367|ensembl:ENSP00000222008|uniprotkb:Q7Z4Y2|uniprotkb:Q9Y3R1	intact:EBI-25278|uniprotkb:D6VVD4|ensemblfungi:YIL153W	psi-mi:praf1_human(display_long)|uniprotkb:PRA1 family protein 1(gene name synonym)|uniprotkb:RABAC1(gene name)|psi-mi:RABAC1(display_short)|uniprotkb:PRA1(gene name synonym)|uniprotkb:PRAF1(gene name synonym)	psi-mi:ptpa1_yeast(display_long)|uniprotkb:YIL153W(locus name)|uniprotkb:RRD1(gene name)|psi-mi:RRD1(display_short)|uniprotkb:NCS1(gene name synonym)|uniprotkb:YPA1(gene name synonym)|uniprotkb:Peptidyl-prolyl cis-trans isomerase PTPA-1(gene name synonym)|uniprotkb:Phosphotyrosyl phosphatase activator 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11541625|imex:IM-24995-2031	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006414.2|ensembl:ENSG00000105404(gene)|ensembl:ENST00000222008(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0070064"(proline-rich region binding)|interpro:IPR004895(Prenylated rab acceptor PRA1)|mint:Q9UI14|entrezgene/locuslink:10567(identity)	refseq:NP_012113.1|sgd:S000001415|mint:P40454|dip:DIP-5663N|ensemblfungi:YIL153W(gene)|ensemblfungi:YIL153W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006914"(autophagy)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008160"(protein tyrosine phosphatase activator activity)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0043618"(regulation of transcription from RNA polymerase II promoter in response to stress)|interpro:IPR004327(Phosphotyrosyl phosphatase activator, PTPA)|interpro:IPR037218|interpro:IPR043170|rcsb pdb:2IXO|rcsb pdb:2IXP|sgd:YIL153W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:WS2rUY7yXRbR7pqWgfUCbnEiDbg9606	rogid:It2q8WlpmvLEZ1fqpRF5Fypw9Q4559292	intact-crc:564D24B3ABE6FF10|rigid:AUXe+NvVLCGB7t8ALTMh9ZY60R4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40454	uniprotkb:Q9NR46	intact:EBI-25278|uniprotkb:D6VVD4|ensemblfungi:YIL153W	intact:EBI-749607|uniprotkb:A8MPS4|uniprotkb:Q8WY61|uniprotkb:Q96JH9|uniprotkb:A6NC47|ensembl:ENSP00000361640|ensembl:ENSP00000361645	psi-mi:ptpa1_yeast(display_long)|uniprotkb:YIL153W(locus name)|uniprotkb:RRD1(gene name)|psi-mi:RRD1(display_short)|uniprotkb:NCS1(gene name synonym)|uniprotkb:YPA1(gene name synonym)|uniprotkb:Peptidyl-prolyl cis-trans isomerase PTPA-1(gene name synonym)|uniprotkb:Phosphotyrosyl phosphatase activator 1(gene name synonym)	psi-mi:shlb2_human(display_long)|uniprotkb:SH3 domain-containing GRB2-like protein B2(gene name synonym)|uniprotkb:SH3GLB2(gene name)|psi-mi:SH3GLB2(display_short)|uniprotkb:KIAA1848(gene name synonym)|uniprotkb:PP578(orf name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11541616|imex:IM-24995-2030	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012113.1|sgd:S000001415|mint:P40454|dip:DIP-5663N|ensemblfungi:YIL153W(gene)|ensemblfungi:YIL153W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006914"(autophagy)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008160"(protein tyrosine phosphatase activator activity)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0043618"(regulation of transcription from RNA polymerase II promoter in response to stress)|interpro:IPR004327(Phosphotyrosyl phosphatase activator, PTPA)|interpro:IPR037218|interpro:IPR043170|rcsb pdb:2IXO|rcsb pdb:2IXP|sgd:YIL153W(identity)	refseq:NP_064530.1|refseq:NP_001273974.1|refseq:NP_001273975.1|refseq:XP_005252158.1|ensembl:ENSG00000148341(gene)|ensembl:ENST00000372559(transcript)|ensembl:ENST00000372564(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|interpro:IPR001452(Src homology-3)|interpro:IPR004148(BAR)|interpro:IPR027267|interpro:IPR035640|interpro:IPR036028|mint:Q9NR46|entrezgene/locuslink:56904(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:It2q8WlpmvLEZ1fqpRF5Fypw9Q4559292	rogid:9C0QF9xLb5A6eYQBK2aU/J1aGVo9606	intact-crc:D5685BB77146FCA1|rigid:HyVSTToe8JVRRQ/VlG5SkOii4/4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9H257-2	uniprotkb:P40454	intact:EBI-11530605|ensembl:ENSP00000360799	intact:EBI-25278|uniprotkb:D6VVD4|ensemblfungi:YIL153W	psi-mi:q9h257-2(display_long)|uniprotkb:CARD9(gene name)|psi-mi:CARD9(display_short)	psi-mi:ptpa1_yeast(display_long)|uniprotkb:YIL153W(locus name)|uniprotkb:RRD1(gene name)|psi-mi:RRD1(display_short)|uniprotkb:NCS1(gene name synonym)|uniprotkb:YPA1(gene name synonym)|uniprotkb:Peptidyl-prolyl cis-trans isomerase PTPA-1(gene name synonym)|uniprotkb:Phosphotyrosyl phosphatase activator 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11541607|imex:IM-24995-2029	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-751319(isoform-parent)|uniprotkb:Q9H257-2(isoform-parent)|ensembl:ENSG00000187796(gene)|ensembl:ENST00000371734(transcript)|entrezgene/locuslink:64170(identity)	refseq:NP_012113.1|sgd:S000001415|mint:P40454|dip:DIP-5663N|ensemblfungi:YIL153W(gene)|ensemblfungi:YIL153W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006914"(autophagy)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008160"(protein tyrosine phosphatase activator activity)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0043618"(regulation of transcription from RNA polymerase II promoter in response to stress)|interpro:IPR004327(Phosphotyrosyl phosphatase activator, PTPA)|interpro:IPR037218|interpro:IPR043170|rcsb pdb:2IXO|rcsb pdb:2IXP|sgd:YIL153W(identity)	-	isoform-comment:No experimental confirmation available.	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:ZXH7B3K5NAzF1LZaeK50ciH1RTE9606	rogid:It2q8WlpmvLEZ1fqpRF5Fypw9Q4559292	intact-crc:04DEDE61C896CD7D|rigid:2z6QF0mbGBZcvk5p+cUtRMrS6YM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40454	uniprotkb:Q9BRK4	intact:EBI-25278|uniprotkb:D6VVD4|ensemblfungi:YIL153W	intact:EBI-741037|ensembl:ENSP00000359240|ensembl:ENSP00000359243|uniprotkb:Q8N3I0|uniprotkb:Q96J79|uniprotkb:Q96JL2|uniprotkb:B1AL14|uniprotkb:D3DR72	psi-mi:ptpa1_yeast(display_long)|uniprotkb:YIL153W(locus name)|uniprotkb:RRD1(gene name)|psi-mi:RRD1(display_short)|uniprotkb:NCS1(gene name synonym)|uniprotkb:YPA1(gene name synonym)|uniprotkb:Peptidyl-prolyl cis-trans isomerase PTPA-1(gene name synonym)|uniprotkb:Phosphotyrosyl phosphatase activator 1(gene name synonym)	psi-mi:lzts2_human(display_long)|uniprotkb:Protein LAPSER1(gene name synonym)|uniprotkb:LZTS2(gene name)|psi-mi:LZTS2(display_short)|uniprotkb:KIAA1813(gene name synonym)|uniprotkb:LAPSER1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11541598|imex:IM-24995-2028	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012113.1|sgd:S000001415|mint:P40454|dip:DIP-5663N|ensemblfungi:YIL153W(gene)|ensemblfungi:YIL153W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006914"(autophagy)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008160"(protein tyrosine phosphatase activator activity)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0043618"(regulation of transcription from RNA polymerase II promoter in response to stress)|interpro:IPR004327(Phosphotyrosyl phosphatase activator, PTPA)|interpro:IPR037218|interpro:IPR043170|rcsb pdb:2IXO|rcsb pdb:2IXP|sgd:YIL153W(identity)	refseq:NP_115805.1|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030496"(midbody)|go:"GO:0031982"(vesicle)|go:"GO:0051013"(microtubule severing)|go:"GO:0051168"(nuclear export)|go:"GO:0051255"(spindle midzone assembly)|go:"GO:0060682"(primary ureteric bud growth)|go:"GO:0072197"(ureter morphogenesis)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|interpro:IPR028597|mint:Q9BRK4|ensembl:ENSG00000107816(gene)|ensembl:ENST00000370220(transcript)|ensembl:ENST00000370223(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0008285"(negative regulation of cell population proliferation)|refseq:XP_016872269.1|refseq:NP_001305028.1|refseq:NP_001305029.1|refseq:NP_001305030.1|refseq:XP_005270279.1|entrezgene/locuslink:84445(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:It2q8WlpmvLEZ1fqpRF5Fypw9Q4559292	rogid:OaMJmnmfm6JniKUJeyg7fS6zRcw9606	intact-crc:73F4918FC2BA8EE3|rigid:vNww3lkR6EPnywLIB41ksn2lzxs	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q93062-3	uniprotkb:P40473	intact:EBI-740343|ensembl:ENSP00000340176	intact:EBI-25207|uniprotkb:D6VVG5|ensemblfungi:YIL122W	psi-mi:q93062-3(display_long)|uniprotkb:RBPMS(gene name)|psi-mi:RBPMS(display_short)|uniprotkb:HERMES(gene name synonym)|uniprotkb:Heart and RRM expressed sequence(gene name synonym)	psi-mi:pog1_yeast(display_long)|uniprotkb:YIL122W(locus name)|uniprotkb:POG1(gene name)|psi-mi:POG1(display_short)|uniprotkb:Promoter of growth protein 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11541768|imex:IM-24995-2046	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-740322(rbpms_human)|uniprotkb:Q93062-3(isoform-parent)|ensembl:ENSG00000157110(gene)|ensembl:ENST00000339877(transcript)|entrezgene/locuslink:11030(identity)	sgd:S000001384|refseq:NP_012144.1|dip:DIP-2755N|ensemblfungi:YIL122W(gene)|ensemblfungi:YIL122W_mRNA(transcript)|go:"GO:0000321"(re-entry into mitotic cell cycle after pheromone arrest)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051301"(cell division)|sgd:YIL122W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:nlPMQAJoKEbPYBwsL3xodmCKd7c9606	rogid:SL7E0QbXBSeu+JDSQhp7p5rNb8M559292	intact-crc:28C3249D2E1D9E80|rigid:LTfvaqT0gfP+tA02L0anJ8XFQLM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40473	uniprotkb:Q6P1W5	intact:EBI-25207|uniprotkb:D6VVG5|ensemblfungi:YIL122W	intact:EBI-946029|uniprotkb:B3KVT1|uniprotkb:Q96IC8|ensembl:ENSP00000435634|uniprotkb:D3DPR3|uniprotkb:E9PJ76	psi-mi:pog1_yeast(display_long)|uniprotkb:YIL122W(locus name)|uniprotkb:POG1(gene name)|psi-mi:POG1(display_short)|uniprotkb:Promoter of growth protein 1(gene name synonym)	psi-mi:ca094_human(display_long)|uniprotkb:C1orf94(gene name)|psi-mi:C1orf94(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11541757|imex:IM-24995-2045	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000001384|refseq:NP_012144.1|dip:DIP-2755N|ensemblfungi:YIL122W(gene)|ensemblfungi:YIL122W_mRNA(transcript)|go:"GO:0000321"(re-entry into mitotic cell cycle after pheromone arrest)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051301"(cell division)|sgd:YIL122W(identity)	refseq:NP_001128206.1|refseq:NP_116273.2|ensembl:ENSG00000142698(gene)|ensembl:ENST00000488417(transcript)|interpro:IPR031496|entrezgene/locuslink:84970(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:SL7E0QbXBSeu+JDSQhp7p5rNb8M559292	rogid:y1o4xWvTl2CBA1J7jsP7y8ZjLzM9606	intact-crc:515EA63F7F75E049|rigid:sNt+ZNXzPZW48djk2nYkVKMe1kc	false	-	sufficient binding region:191-598	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P63279	uniprotkb:P40473	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	intact:EBI-25207|uniprotkb:D6VVG5|ensemblfungi:YIL122W	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:pog1_yeast(display_long)|uniprotkb:YIL122W(locus name)|uniprotkb:POG1(gene name)|psi-mi:POG1(display_short)|uniprotkb:Promoter of growth protein 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11541748|imex:IM-24995-2044	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N|entrezgene/locuslink:7329(identity)	sgd:S000001384|refseq:NP_012144.1|dip:DIP-2755N|ensemblfungi:YIL122W(gene)|ensemblfungi:YIL122W_mRNA(transcript)|go:"GO:0000321"(re-entry into mitotic cell cycle after pheromone arrest)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051301"(cell division)|sgd:YIL122W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	rogid:SL7E0QbXBSeu+JDSQhp7p5rNb8M559292	intact-crc:E43069A8CC40346B|rigid:ex6IWOlG9aqouyaWAdEOM1N7cHs	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96BA8	uniprotkb:P40471	intact:EBI-6942903|ensembl:ENSP00000481956|intact:MINT-268046|intact:MINT-8162577|uniprotkb:Q8N2D5|uniprotkb:Q96CP0	intact:EBI-25213|uniprotkb:D6VVG3|ensemblfungi:YIL124W	psi-mi:cr3l1_human(display_long)|uniprotkb:CREB3L1(gene name)|psi-mi:CREB3L1(display_short)|uniprotkb:OASIS(gene name synonym)|uniprotkb:PSEC0238(orf name)|uniprotkb:Old astrocyte specifically-induced substance(gene name synonym)	psi-mi:ayr1_yeast(display_long)|uniprotkb:AYR1(gene name)|psi-mi:AYR1(display_short)|uniprotkb:Acylglycerone-phosphate reductase(gene name synonym)|uniprotkb:1-acyl DHAP reductase(gene name synonym)|uniprotkb:Acyl/alkyl DHAP reductase(gene name synonym)|uniprotkb:GBG1(gene name synonym)|uniprotkb:Triacylglycerol lipase AYR1(gene name synonym)|uniprotkb:YIL124W(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11541739|imex:IM-24995-2043	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157613(gene)|ensembl:ENST00000621158(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0070278"(extracellular matrix constituent secretion)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029805|mint:Q96BA8|reactome:R-HSA-8874211|refseq:NP_443086.1|entrezgene/locuslink:90993(identity)	sgd:S000001386|refseq:NP_012142.3|mint:P40471|dip:DIP-4614N|ensemblfungi:YIL124W(gene)|ensemblfungi:YIL124W_mRNA(transcript)|go:"GO:0000140"(acylglycerone-phosphate reductase activity)|go:"GO:0004806"(triglyceride lipase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0006654"(phosphatidic acid biosynthetic process)|go:"GO:0019433"(triglyceride catabolic process)|go:"GO:0102566"(1-acyl dihydroxyacetone phosphate reductase activity)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR020904|interpro:IPR036291|sgd:YIL124W(identity)	-	comment:mint|function:"Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE"	crc64:B614C0E0B1FB0CE0	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:sMWUFmBeBBCO+T0Y2CuB/un1lBg9606	rogid:WE4RmSXARj683MNUEsYGLis36Xo559292	intact-crc:625A6CB325BE773C|rigid:PIdRZmUwxOaR2abQ9jw56/9k5Oo	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O14964	uniprotkb:P40460	intact:EBI-740220|uniprotkb:Q9NR36|ensembl:ENSP00000331201|ensembl:ENSP00000504106	intact:EBI-25247|uniprotkb:D6VVE3|ensemblfungi:YIL144W	psi-mi:hgs_human(display_long)|uniprotkb:Protein pp110(gene name synonym)|uniprotkb:Hrs(gene name synonym)|uniprotkb:HGS(gene name)|psi-mi:HGS(display_short)|uniprotkb:HRS(gene name synonym)	psi-mi:ndc80_yeast(display_long)|uniprotkb:NDC80(gene name)|psi-mi:NDC80(display_short)|uniprotkb:80 kDa spindle component protein(gene name synonym)|uniprotkb:HEC1(gene name synonym)|uniprotkb:Nuclear division cycle protein 80(gene name synonym)|uniprotkb:TID3(gene name synonym)|uniprotkb:Two-hybrid interaction with DMC1 protein 3(gene name synonym)|uniprotkb:YIL144W(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11541730|imex:IM-24995-2042	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004703.1|dip:DIP-29050N|ensembl:ENSG00000185359(gene)|ensembl:ENST00000329138(transcript)|ensembl:ENST00000676546(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0007165"(signal transduction)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010324"(membrane invagination)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010642"(negative regulation of platelet-derived growth factor receptor signaling pathway)|go:"GO:0016197"(endosomal transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032585"(multivesicular body membrane)|go:"GO:0033565"(ESCRT-0 complex)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043405"(regulation of MAP kinase activity)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072657"(protein localization to membrane)|go:"GO:0097013"(phagocytic vesicle lumen)|go:"GO:1903543"(positive regulation of exosomal secretion)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR002014(VHS)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017073(Ubiquitin binding protein, Hrs/VPS27)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR024641|mint:O14964|rcsb pdb:2D3G|rcsb pdb:3F1I|rcsb pdb:3OBQ|rcsb pdb:3ZYQ|rcsb pdb:4AVX|reactome:R-HSA-182971|reactome:R-HSA-432720|reactome:R-HSA-5689880|reactome:R-HSA-6807004|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8875360|reactome:R-HSA-9013420|reactome:R-HSA-917729|reactome:R-HSA-9635644|reactome:R-HSA-9636383|reactome:R-HSA-9706019|entrezgene/locuslink:9146(identity)	sgd:S000001406|refseq:NP_012122.3|mint:P40460|dip:DIP-818N|ensemblfungi:YIL144W(gene)|ensemblfungi:YIL144W_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0007059"(chromosome segregation)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0042802"(identical protein binding)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|interpro:IPR005550(HEC/Ndc80p)|interpro:IPR038273|interpro:IPR040967|rcsb pdb:5TCS|rcsb pdb:5TD8|rcsb pdb:7KDF|sgd:YIL144W(identity)	-	-	crc64:7DBC492227A80093	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:z/AnREuqEpyJ9/Zj6JFCJCJem1I9606	rogid:ZrT7N4pBKz6upSglhGhOqgeoAYw559292	intact-crc:7892DA51C847204C|rigid:q6e4XfVFovWkoLeZrXGfwCTLUAU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40455	uniprotkb:Q9Y3Q8	intact:EBI-25274|uniprotkb:D6VVD5|ensemblfungi:YIL152W	intact:EBI-739485|uniprotkb:A8MWR6|ensembl:ENSP00000300181|uniprotkb:A4D2C3|uniprotkb:D6W5V9	psi-mi:yip2_yeast(display_long)|uniprotkb:YIL152W(locus name)	psi-mi:t22d4_human(display_long)|uniprotkb:TSC22D4(gene name)|psi-mi:TSC22D4(display_short)|uniprotkb:TILZ2(gene name synonym)|uniprotkb:TSC22-related-inducible leucine zipper protein 2(gene name synonym)|uniprotkb:Tsc-22-like protein THG-1(gene name synonym)|uniprotkb:THG1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11541721|imex:IM-24995-2041	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000001414|refseq:NP_012114.1|mint:P40455|dip:DIP-2047N|ensemblfungi:YIL152W(gene)|ensemblfungi:YIL152W_mRNA(transcript)|sgd:YIL152W(identity)	ensembl:ENSG00000166925(gene)|ensembl:ENST00000300181(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006970"(response to osmotic stress)|interpro:IPR000580(TSC-22 / Dip / Bun)|interpro:IPR042553|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|refseq:NP_112197.1|refseq:NP_001289972.1|entrezgene/locuslink:81628(identity)	-	crc64:07550E3F491F53A8	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:t5hCm1ck6kpFUxpEd8CsyLrHbEw559292	rogid:eL12cHY76zEPOXzT1HFKPSckS8Y9606	intact-crc:0AE76C2DA83D3A54|rigid:PGN/CnxnWOmURFFkj+OFUHbLKt4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40455	uniprotkb:Q9BRK4	intact:EBI-25274|uniprotkb:D6VVD5|ensemblfungi:YIL152W	intact:EBI-741037|ensembl:ENSP00000359240|ensembl:ENSP00000359243|uniprotkb:Q8N3I0|uniprotkb:Q96J79|uniprotkb:Q96JL2|uniprotkb:B1AL14|uniprotkb:D3DR72	psi-mi:yip2_yeast(display_long)|uniprotkb:YIL152W(locus name)	psi-mi:lzts2_human(display_long)|uniprotkb:Protein LAPSER1(gene name synonym)|uniprotkb:LZTS2(gene name)|psi-mi:LZTS2(display_short)|uniprotkb:KIAA1813(gene name synonym)|uniprotkb:LAPSER1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11541712|imex:IM-24995-2040	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000001414|refseq:NP_012114.1|mint:P40455|dip:DIP-2047N|ensemblfungi:YIL152W(gene)|ensemblfungi:YIL152W_mRNA(transcript)|sgd:YIL152W(identity)	refseq:NP_115805.1|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030496"(midbody)|go:"GO:0031982"(vesicle)|go:"GO:0051013"(microtubule severing)|go:"GO:0051168"(nuclear export)|go:"GO:0051255"(spindle midzone assembly)|go:"GO:0060682"(primary ureteric bud growth)|go:"GO:0072197"(ureter morphogenesis)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|interpro:IPR028597|mint:Q9BRK4|ensembl:ENSG00000107816(gene)|ensembl:ENST00000370220(transcript)|ensembl:ENST00000370223(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0008285"(negative regulation of cell population proliferation)|refseq:XP_016872269.1|refseq:NP_001305028.1|refseq:NP_001305029.1|refseq:NP_001305030.1|refseq:XP_005270279.1|entrezgene/locuslink:84445(identity)	-	crc64:07550E3F491F53A8	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:t5hCm1ck6kpFUxpEd8CsyLrHbEw559292	rogid:OaMJmnmfm6JniKUJeyg7fS6zRcw9606	intact-crc:1B7406F3F171BB3C|rigid:GoCOO6g/qfkgYjYzvQ4SGVZo+/Y	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40455	uniprotkb:Q8N9N5-2	intact:EBI-25274|uniprotkb:D6VVD5|ensemblfungi:YIL152W	intact:EBI-11524452|ensembl:ENSP00000347125	psi-mi:yip2_yeast(display_long)|uniprotkb:YIL152W(locus name)	psi-mi:q8n9n5-2(display_long)|uniprotkb:BANP(gene name)|psi-mi:BANP(display_short)|uniprotkb:BEN domain-containing protein 1(gene name synonym)|uniprotkb:BEND1(gene name synonym)|uniprotkb:Btg3-associated nuclear protein(gene name synonym)|uniprotkb:SMAR1(gene name synonym)|uniprotkb:Scaffold/matrix-associated region-1-binding protein(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11541703|imex:IM-24995-2039	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000001414|refseq:NP_012114.1|mint:P40455|dip:DIP-2047N|ensemblfungi:YIL152W(gene)|ensemblfungi:YIL152W_mRNA(transcript)|sgd:YIL152W(identity)	ensembl:ENSG00000172530(gene)|ensembl:ENST00000355022(transcript)|intact:EBI-744695(isoform-parent)|uniprotkb:Q8N9N5-2(isoform-parent)|entrezgene/locuslink:54971(identity)	-	crc64:07550E3F491F53A8	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:t5hCm1ck6kpFUxpEd8CsyLrHbEw559292	rogid:ESe6iCAhvq+i57fQHz3rGyg6UOo9606	intact-crc:2BE1EB5C927F81C0|rigid:Y6m8Umk009Rd1Pv4uhcYS7loBOg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q5JR59-3	uniprotkb:P40455	intact:EBI-11522433|ensembl:ENSP00000370186	intact:EBI-25274|uniprotkb:D6VVD5|ensemblfungi:YIL152W	psi-mi:q5jr59-3(display_long)|uniprotkb:MTUS2(gene name)|psi-mi:MTUS2(display_short)|uniprotkb:CAZIP(gene name synonym)|uniprotkb:Cardiac zipper protein(gene name synonym)|uniprotkb:KIAA0774(gene name synonym)|uniprotkb:Microtubule plus-end tracking protein TIP150(gene name synonym)|uniprotkb:TIP150(gene name synonym)	psi-mi:yip2_yeast(display_long)|uniprotkb:YIL152W(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11541694|imex:IM-24995-2038	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000132938(gene)|ensembl:ENST00000380808(transcript)|intact:EBI-742948(isoform-parent)|uniprotkb:Q5JR59-3(isoform-parent)|entrezgene/locuslink:23281(identity)	sgd:S000001414|refseq:NP_012114.1|mint:P40455|dip:DIP-2047N|ensemblfungi:YIL152W(gene)|ensemblfungi:YIL152W_mRNA(transcript)|sgd:YIL152W(identity)	-	isoform-comment:No experimental confirmation available.	crc64:07550E3F491F53A8	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:npId9tC7VoLN/jteoBiRbSYChPs9606	rogid:t5hCm1ck6kpFUxpEd8CsyLrHbEw559292	intact-crc:1212A4A0F0B114D7|rigid:rDuZDZJuGb65exhgQM2kW3j5YMI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O14641	uniprotkb:P40455	intact:EBI-740850|ensembl:ENSP00000005340|uniprotkb:Q53XM0|uniprotkb:D3DTN3	intact:EBI-25274|uniprotkb:D6VVD5|ensemblfungi:YIL152W	psi-mi:dvl2_human(display_long)|uniprotkb:DSH homolog 2(gene name synonym)|uniprotkb:DVL2(gene name)|psi-mi:DVL2(display_short)	psi-mi:yip2_yeast(display_long)|uniprotkb:YIL152W(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11541685|imex:IM-24995-2037	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004413.1|ensembl:ENSG00000004975(gene)|ensembl:ENST00000005340(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005109"(frizzled binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0007507"(heart development)|go:"GO:0016235"(aggresome)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044340"(canonical Wnt signaling pathway involved in regulation of cell proliferation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0150012"(positive regulation of neuron projection arborization)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008341(Dishevelled-2 region)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:O14641|rcsb pdb:2REY|rcsb pdb:3CBX|rcsb pdb:3CBY|rcsb pdb:3CBZ|rcsb pdb:3CC0|rcsb pdb:4WIP|rcsb pdb:5LNP|rcsb pdb:5SUY|rcsb pdb:5SUZ|rcsb pdb:6IW3|rcsb pdb:6JCK|reactome:R-HSA-201681|reactome:R-HSA-201688|reactome:R-HSA-2028269|reactome:R-HSA-4086400|reactome:R-HSA-4608870|reactome:R-HSA-4641258|reactome:R-HSA-4641262|reactome:R-HSA-5099900|reactome:R-HSA-5368598|reactome:R-HSA-5663220|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9673324|ensembl:ENSP00000005340|dip:DIP-34433N|entrezgene/locuslink:1856(identity)	sgd:S000001414|refseq:NP_012114.1|mint:P40455|dip:DIP-2047N|ensemblfungi:YIL152W(gene)|ensemblfungi:YIL152W_mRNA(transcript)|sgd:YIL152W(identity)	-	-	crc64:07550E3F491F53A8	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:2Vdc8oRnT4Mz/j+EXQXrL3AszOc9606	rogid:t5hCm1ck6kpFUxpEd8CsyLrHbEw559292	intact-crc:201E27E37FF22E65|rigid:6KNcHMZ71nkyff8OYwPyQlhJ8vA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O43186	uniprotkb:P40482	intact:EBI-748171|uniprotkb:Q0QD45|ensembl:ENSP00000221996|ensembl:ENSP00000445565	intact:EBI-16592|ensemblfungi:YIL109C|uniprotkb:D6VVH8	psi-mi:crx_human(display_long)|uniprotkb:CRX(gene name)|psi-mi:CRX(display_short)|uniprotkb:CORD2(gene name synonym)	psi-mi:sec24_yeast(display_long)|uniprotkb:SEC24(gene name)|psi-mi:SEC24(display_short)|uniprotkb:Abnormal nuclear morphology 1(gene name synonym)|uniprotkb:ANU1(gene name synonym)|uniprotkb:YIL109C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11541788|imex:IM-24995-2048	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000545.1|ensembl:ENSG00000105392(gene)|ensembl:ENST00000221996(transcript)|ensembl:ENST00000539067(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007601"(visual perception)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050896"(response to stimulus)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013851(Transcription factor Otx, C-terminal)|interpro:IPR017970|entrezgene/locuslink:1406(identity)	refseq:NP_012157.3|ensemblfungi:YIL109C(gene)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016236"(macroautophagy)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0070971"(endoplasmic reticulum exit site)|ensemblfungi:YIL109C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0090110"(COPII-coated vesicle cargo loading)|interpro:IPR006895(Zinc finger, Sec23/Sec24-type)|interpro:IPR006896(Sec23/Sec24 trunk region)|interpro:IPR006900(Sec23/Sec24 helical region)|interpro:IPR007123(Gelsolin region)|interpro:IPR012990(Sec23/Sec24 beta-sandwich)|interpro:IPR029006|interpro:IPR036174|interpro:IPR036175|interpro:IPR036180|go:"GO:0000149"(SNARE binding)|go:"GO:0000329"(fungal-type vacuole membrane)|interpro:IPR036465|interpro:IPR041742|rcsb pdb:1M2V|rcsb pdb:1PCX|rcsb pdb:1PD0|rcsb pdb:1PD1|rcsb pdb:4BZI|rcsb pdb:6GNI|rcsb pdb:6ZGA|reactome:R-SCE-204005|reactome:R-SCE-5694530|reactome:R-SCE-983170|go:"GO:0005048"(signal sequence binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|sgd:S000001371|dip:DIP-2233N|mint:P40482|sgd:YIL109C(identity)	-	-	crc64:35E2BDD24CC75899	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:v/bkO/0iLzq1Q2HtieWQQ40RF9M9606	rogid:e7ekVFzZJMZvfRUZ9Q2jDQ/hvs0559292	intact-crc:50566AC65509EB3F|rigid:9K4xOQkvhSsK+w7VgSKN3FAe70Y	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:G5E962	uniprotkb:P40481	intact:EBI-11525615|ensembl:ENSP00000328177	intact:EBI-25180|uniprotkb:D6VVH7|ensemblfungi:YIL110W	psi-mi:g5e962_human(display_long)|uniprotkb:hCG_1644200(orf name)|uniprotkb:MAGEA11(gene name)|psi-mi:MAGEA11(display_short)	psi-mi:hpm1_yeast(display_long)|uniprotkb:MNI1(gene name synonym)|uniprotkb:YIL110W(locus name)|uniprotkb:HPM1(gene name)|psi-mi:HPM1(display_short)|uniprotkb:Mitotic exit network interactor 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11541777|imex:IM-24995-2047	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001011544.1|ensembl:ENSG00000185247(gene)|ensembl:ENST00000333104(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016604"(nuclear body)|interpro:IPR002190(MAGE protein)|interpro:IPR021072|interpro:IPR030099|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|entrezgene/locuslink:4110(identity)	refseq:NP_012156.1|sgd:S000001372|dip:DIP-4710N|ensemblfungi:YIL110W(gene)|ensemblfungi:YIL110W_mRNA(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0018064"(protein-L-histidine N-tele-methyltransferase activity)|go:"GO:0042038"(peptidyl-histidine methylation, to form tele-methylhistidine)|go:"GO:0045903"(positive regulation of translational fidelity)|interpro:IPR019410|sgd:YIL110W(identity)	-	-	crc64:C90C67433B5BCA7A	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:sVB0aA6yibWUx/d2SE+pwpKKgtI9606	rogid:hoAVij8oaANAGDSPMwh+IW39rn8559292	intact-crc:1CB67CA3D7C5932F|rigid:mtUIaU+R0fXUT35sYcjU6W1thdo	false	sufficient binding region:82-400	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40482	uniprotkb:Q9Y2W2	intact:EBI-16592|ensemblfungi:YIL109C|uniprotkb:D6VVH8	intact:EBI-714455|ensembl:ENSP00000261167|uniprotkb:Q96AY8	psi-mi:sec24_yeast(display_long)|uniprotkb:SEC24(gene name)|psi-mi:SEC24(display_short)|uniprotkb:Abnormal nuclear morphology 1(gene name synonym)|uniprotkb:ANU1(gene name synonym)|uniprotkb:YIL109C(locus name)	psi-mi:wbp11_human(display_long)|uniprotkb:SH3 domain-binding protein SNP70(gene name synonym)|uniprotkb:Npw38-binding protein(gene name synonym)|uniprotkb:WBP11(gene name)|psi-mi:WBP11(display_short)|uniprotkb:NPWBP(gene name synonym)|uniprotkb:SNP70(gene name synonym)|uniprotkb:SIPP1(gene name synonym)|uniprotkb:Splicing factor that interacts with PQBP-1 and PP1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11541862|imex:IM-24995-2056	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012157.3|ensemblfungi:YIL109C(gene)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016236"(macroautophagy)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0070971"(endoplasmic reticulum exit site)|ensemblfungi:YIL109C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0090110"(COPII-coated vesicle cargo loading)|interpro:IPR006895(Zinc finger, Sec23/Sec24-type)|interpro:IPR006896(Sec23/Sec24 trunk region)|interpro:IPR006900(Sec23/Sec24 helical region)|interpro:IPR007123(Gelsolin region)|interpro:IPR012990(Sec23/Sec24 beta-sandwich)|interpro:IPR029006|interpro:IPR036174|interpro:IPR036175|interpro:IPR036180|go:"GO:0000149"(SNARE binding)|go:"GO:0000329"(fungal-type vacuole membrane)|interpro:IPR036465|interpro:IPR041742|rcsb pdb:1M2V|rcsb pdb:1PCX|rcsb pdb:1PD0|rcsb pdb:1PD1|rcsb pdb:4BZI|rcsb pdb:6GNI|rcsb pdb:6ZGA|reactome:R-SCE-204005|reactome:R-SCE-5694530|reactome:R-SCE-983170|go:"GO:0005048"(signal sequence binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|sgd:S000001371|dip:DIP-2233N|mint:P40482|sgd:YIL109C(identity)	rcsb pdb:7ABG|reactome:R-HSA-72163|ensembl:ENSG00000084463(gene)|ensembl:ENST00000261167(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045292"(mRNA cis splicing, via spliceosome)|go:"GO:0050699"(WW domain binding)|interpro:IPR019007|mint:Q9Y2W2|rcsb pdb:7ABF|refseq:NP_057396.1|entrezgene/locuslink:51729(identity)	-	crc64:35E2BDD24CC75899	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:e7ekVFzZJMZvfRUZ9Q2jDQ/hvs0559292	rogid:qE03bpSsQiJouJbn6ISt8DnD/pA9606	intact-crc:A9B7BAD4EC10AD7B|rigid:dzrYIXOOYHA8fIJECJRnipXxixE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40482	uniprotkb:Q9UPT5-1	intact:EBI-16592|ensemblfungi:YIL109C|uniprotkb:D6VVH8	intact:EBI-6251402|ensembl:ENSP00000468404	psi-mi:sec24_yeast(display_long)|uniprotkb:SEC24(gene name)|psi-mi:SEC24(display_short)|uniprotkb:Abnormal nuclear morphology 1(gene name synonym)|uniprotkb:ANU1(gene name synonym)|uniprotkb:YIL109C(locus name)	psi-mi:q9upt5-1(display_long)|uniprotkb:EXOC7(gene name)|psi-mi:EXOC7(display_short)|uniprotkb:EXO70(gene name synonym)|uniprotkb:KIAA1067(gene name synonym)|uniprotkb:Exocyst complex component Exo70(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11541853|imex:IM-24995-2055	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012157.3|ensemblfungi:YIL109C(gene)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016236"(macroautophagy)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0070971"(endoplasmic reticulum exit site)|ensemblfungi:YIL109C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0090110"(COPII-coated vesicle cargo loading)|interpro:IPR006895(Zinc finger, Sec23/Sec24-type)|interpro:IPR006896(Sec23/Sec24 trunk region)|interpro:IPR006900(Sec23/Sec24 helical region)|interpro:IPR007123(Gelsolin region)|interpro:IPR012990(Sec23/Sec24 beta-sandwich)|interpro:IPR029006|interpro:IPR036174|interpro:IPR036175|interpro:IPR036180|go:"GO:0000149"(SNARE binding)|go:"GO:0000329"(fungal-type vacuole membrane)|interpro:IPR036465|interpro:IPR041742|rcsb pdb:1M2V|rcsb pdb:1PCX|rcsb pdb:1PD0|rcsb pdb:1PD1|rcsb pdb:4BZI|rcsb pdb:6GNI|rcsb pdb:6ZGA|reactome:R-SCE-204005|reactome:R-SCE-5694530|reactome:R-SCE-983170|go:"GO:0005048"(signal sequence binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|sgd:S000001371|dip:DIP-2233N|mint:P40482|sgd:YIL109C(identity)	ensembl:ENSG00000182473(gene)|ensembl:ENST00000589210(transcript)|intact:EBI-720048(isoform-parent)|uniprotkb:Q9UPT5-1(isoform-parent)|entrezgene/locuslink:23265(identity)	-	crc64:35E2BDD24CC75899	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:e7ekVFzZJMZvfRUZ9Q2jDQ/hvs0559292	rogid:CKIeTOGXIWrHA1Duuw7x1ycRPoc9606	intact-crc:2B9CCC557FD51490|rigid:2Mrw3Ks+1DL9VaeNNYSumHGSw9g	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40482	uniprotkb:Q9BYV6-2	intact:EBI-16592|ensemblfungi:YIL109C|uniprotkb:D6VVH8	intact:EBI-11522718|ensembl:ENSP00000297348	psi-mi:sec24_yeast(display_long)|uniprotkb:SEC24(gene name)|psi-mi:SEC24(display_short)|uniprotkb:Abnormal nuclear morphology 1(gene name synonym)|uniprotkb:ANU1(gene name synonym)|uniprotkb:YIL109C(locus name)	psi-mi:q9byv6-2(display_long)|uniprotkb:TRIM55(gene name)|psi-mi:TRIM55(display_short)|uniprotkb:MURF2(gene name synonym)|uniprotkb:Muscle-specific RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 29(gene name synonym)|uniprotkb:RNF29(gene name synonym)|uniprotkb:p50(isoform synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11541844|imex:IM-24995-2054	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012157.3|ensemblfungi:YIL109C(gene)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016236"(macroautophagy)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0070971"(endoplasmic reticulum exit site)|ensemblfungi:YIL109C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0090110"(COPII-coated vesicle cargo loading)|interpro:IPR006895(Zinc finger, Sec23/Sec24-type)|interpro:IPR006896(Sec23/Sec24 trunk region)|interpro:IPR006900(Sec23/Sec24 helical region)|interpro:IPR007123(Gelsolin region)|interpro:IPR012990(Sec23/Sec24 beta-sandwich)|interpro:IPR029006|interpro:IPR036174|interpro:IPR036175|interpro:IPR036180|go:"GO:0000149"(SNARE binding)|go:"GO:0000329"(fungal-type vacuole membrane)|interpro:IPR036465|interpro:IPR041742|rcsb pdb:1M2V|rcsb pdb:1PCX|rcsb pdb:1PD0|rcsb pdb:1PD1|rcsb pdb:4BZI|rcsb pdb:6GNI|rcsb pdb:6ZGA|reactome:R-SCE-204005|reactome:R-SCE-5694530|reactome:R-SCE-983170|go:"GO:0005048"(signal sequence binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|sgd:S000001371|dip:DIP-2233N|mint:P40482|sgd:YIL109C(identity)	intact:EBI-2341179(isoform-parent)|uniprotkb:Q9BYV6-2(isoform-parent)|ensembl:ENSG00000147573(gene)|ensembl:ENST00000353317(transcript)|entrezgene/locuslink:84675(identity)	-	crc64:35E2BDD24CC75899	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:e7ekVFzZJMZvfRUZ9Q2jDQ/hvs0559292	rogid:9t8UhK+Z1yBqjnQrOqPD76NuXGg9606	intact-crc:AD016362B11C2645|rigid:KagW2q0P9FpPsKOn82dMJCHzfjw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96BR9	uniprotkb:P40482	intact:EBI-742740|uniprotkb:Q8IUL5|uniprotkb:Q8IWR9|uniprotkb:Q8N2Y5|uniprotkb:Q96BX0|ensembl:ENSP00000362609	intact:EBI-16592|ensemblfungi:YIL109C|uniprotkb:D6VVH8	psi-mi:zbt8a_human(display_long)|uniprotkb:ZBTB8A(gene name)|psi-mi:ZBTB8A(display_short)|uniprotkb:BOZF1(gene name synonym)|uniprotkb:BTB/POZ and zinc-finger domain-containing factor(gene name synonym)|uniprotkb:BTB/POZ and zinc-finger domains factor on chromosome 1(gene name synonym)	psi-mi:sec24_yeast(display_long)|uniprotkb:SEC24(gene name)|psi-mi:SEC24(display_short)|uniprotkb:Abnormal nuclear morphology 1(gene name synonym)|uniprotkb:ANU1(gene name synonym)|uniprotkb:YIL109C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11541835|imex:IM-24995-2053	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000160062(gene)|ensembl:ENST00000373510(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|refseq:NP_001035531.2|refseq:NP_001278425.1|entrezgene/locuslink:653121(identity)	refseq:NP_012157.3|ensemblfungi:YIL109C(gene)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016236"(macroautophagy)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0070971"(endoplasmic reticulum exit site)|ensemblfungi:YIL109C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0090110"(COPII-coated vesicle cargo loading)|interpro:IPR006895(Zinc finger, Sec23/Sec24-type)|interpro:IPR006896(Sec23/Sec24 trunk region)|interpro:IPR006900(Sec23/Sec24 helical region)|interpro:IPR007123(Gelsolin region)|interpro:IPR012990(Sec23/Sec24 beta-sandwich)|interpro:IPR029006|interpro:IPR036174|interpro:IPR036175|interpro:IPR036180|go:"GO:0000149"(SNARE binding)|go:"GO:0000329"(fungal-type vacuole membrane)|interpro:IPR036465|interpro:IPR041742|rcsb pdb:1M2V|rcsb pdb:1PCX|rcsb pdb:1PD0|rcsb pdb:1PD1|rcsb pdb:4BZI|rcsb pdb:6GNI|rcsb pdb:6ZGA|reactome:R-SCE-204005|reactome:R-SCE-5694530|reactome:R-SCE-983170|go:"GO:0005048"(signal sequence binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|sgd:S000001371|dip:DIP-2233N|mint:P40482|sgd:YIL109C(identity)	-	-	crc64:35E2BDD24CC75899	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:tsrPT2tHvuBryODKgRXnceXz9s09606	rogid:e7ekVFzZJMZvfRUZ9Q2jDQ/hvs0559292	intact-crc:B0E0005428594051|rigid:TGMPKDd80thAEsAmUjkZybJMmFc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40482	uniprotkb:Q5T124-6	intact:EBI-16592|ensemblfungi:YIL109C|uniprotkb:D6VVH8	intact:EBI-11524408	psi-mi:sec24_yeast(display_long)|uniprotkb:SEC24(gene name)|psi-mi:SEC24(display_short)|uniprotkb:Abnormal nuclear morphology 1(gene name synonym)|uniprotkb:ANU1(gene name synonym)|uniprotkb:YIL109C(locus name)	psi-mi:q5t124-6(display_long)|uniprotkb:UBXN11(gene name)|psi-mi:UBXN11(display_short)|uniprotkb:Colorectal tumor-associated antigen COA-1(gene name synonym)|uniprotkb:SOC(gene name synonym)|uniprotkb:Socius(gene name synonym)|uniprotkb:UBX domain-containing protein 5(gene name synonym)|uniprotkb:UBXD5(gene name synonym)|uniprotkb:PP2243(orf name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11541826|imex:IM-24995-2052	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012157.3|ensemblfungi:YIL109C(gene)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016236"(macroautophagy)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0070971"(endoplasmic reticulum exit site)|ensemblfungi:YIL109C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0090110"(COPII-coated vesicle cargo loading)|interpro:IPR006895(Zinc finger, Sec23/Sec24-type)|interpro:IPR006896(Sec23/Sec24 trunk region)|interpro:IPR006900(Sec23/Sec24 helical region)|interpro:IPR007123(Gelsolin region)|interpro:IPR012990(Sec23/Sec24 beta-sandwich)|interpro:IPR029006|interpro:IPR036174|interpro:IPR036175|interpro:IPR036180|go:"GO:0000149"(SNARE binding)|go:"GO:0000329"(fungal-type vacuole membrane)|interpro:IPR036465|interpro:IPR041742|rcsb pdb:1M2V|rcsb pdb:1PCX|rcsb pdb:1PD0|rcsb pdb:1PD1|rcsb pdb:4BZI|rcsb pdb:6GNI|rcsb pdb:6ZGA|reactome:R-SCE-204005|reactome:R-SCE-5694530|reactome:R-SCE-983170|go:"GO:0005048"(signal sequence binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|sgd:S000001371|dip:DIP-2233N|mint:P40482|sgd:YIL109C(identity)	intact:EBI-746004(isoform-parent)|uniprotkb:Q5T124-6(isoform-parent)|entrezgene/locuslink:91544(identity)	-	crc64:35E2BDD24CC75899	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:e7ekVFzZJMZvfRUZ9Q2jDQ/hvs0559292	rogid:1YSjG/p2ihcjl4P8KdPCaX2HxiY9606	intact-crc:F37C35596DF1B97B|rigid:9dTYfYSi8mp0xvSI86f7WG71xgw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40482	uniprotkb:Q5JST6	intact:EBI-16592|ensemblfungi:YIL109C|uniprotkb:D6VVH8	intact:EBI-2349927|uniprotkb:Q9H653|uniprotkb:Q5JST8|uniprotkb:Q68DK4|uniprotkb:Q8NEI0|intact:EBI-28971886|ensembl:ENSP00000404232	psi-mi:sec24_yeast(display_long)|uniprotkb:SEC24(gene name)|psi-mi:SEC24(display_short)|uniprotkb:Abnormal nuclear morphology 1(gene name synonym)|uniprotkb:ANU1(gene name synonym)|uniprotkb:YIL109C(locus name)	psi-mi:efhc2_human(display_long)|uniprotkb:EFHC2(gene name)|psi-mi:EFHC2(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11541817|imex:IM-24995-2051	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012157.3|ensemblfungi:YIL109C(gene)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016236"(macroautophagy)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0070971"(endoplasmic reticulum exit site)|ensemblfungi:YIL109C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0090110"(COPII-coated vesicle cargo loading)|interpro:IPR006895(Zinc finger, Sec23/Sec24-type)|interpro:IPR006896(Sec23/Sec24 trunk region)|interpro:IPR006900(Sec23/Sec24 helical region)|interpro:IPR007123(Gelsolin region)|interpro:IPR012990(Sec23/Sec24 beta-sandwich)|interpro:IPR029006|interpro:IPR036174|interpro:IPR036175|interpro:IPR036180|go:"GO:0000149"(SNARE binding)|go:"GO:0000329"(fungal-type vacuole membrane)|interpro:IPR036465|interpro:IPR041742|rcsb pdb:1M2V|rcsb pdb:1PCX|rcsb pdb:1PD0|rcsb pdb:1PD1|rcsb pdb:4BZI|rcsb pdb:6GNI|rcsb pdb:6ZGA|reactome:R-SCE-204005|reactome:R-SCE-5694530|reactome:R-SCE-983170|go:"GO:0005048"(signal sequence binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|sgd:S000001371|dip:DIP-2233N|mint:P40482|sgd:YIL109C(identity)	ensembl:ENSP00000404232|refseq:NP_079460.2|ensembl:ENSG00000183690(gene)|ensembl:ENST00000420999(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005930"(axoneme)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0060285"(cilium-dependent cell motility)|go:"GO:0072686"(mitotic spindle)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR006602(Region of unknown function DM10)|interpro:IPR011992(EF-Hand type)|interpro:IPR040193|rcsb pdb:2Z13|rcsb pdb:2Z14|entrezgene/locuslink:80258(identity)	-	crc64:35E2BDD24CC75899	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:e7ekVFzZJMZvfRUZ9Q2jDQ/hvs0559292	rogid:O1XriQSkLcYkk7H7AlanQ1FKIBY9606	intact-crc:5CACA8B380F0354A|rigid:K+jf9WcEspZ15KZ93IpZr04HG7I	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40482	uniprotkb:P48775	intact:EBI-16592|ensemblfungi:YIL109C|uniprotkb:D6VVH8	intact:EBI-743494|ensembl:ENSP00000444788|ensembl:ENSP00000460086|uniprotkb:A8K053	psi-mi:sec24_yeast(display_long)|uniprotkb:SEC24(gene name)|psi-mi:SEC24(display_short)|uniprotkb:Abnormal nuclear morphology 1(gene name synonym)|uniprotkb:ANU1(gene name synonym)|uniprotkb:YIL109C(locus name)	psi-mi:t23o_human(display_long)|uniprotkb:Tryptophan pyrrolase(gene name synonym)|uniprotkb:Tryptophan oxygenase(gene name synonym)|uniprotkb:Tryptamin 2,3-dioxygenase(gene name synonym)|uniprotkb:TDO2(gene name)|psi-mi:TDO2(display_short)|uniprotkb:TDO(gene name synonym)|uniprotkb:Tryptophanase(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11541808|imex:IM-24995-2050	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012157.3|ensemblfungi:YIL109C(gene)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016236"(macroautophagy)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0070971"(endoplasmic reticulum exit site)|ensemblfungi:YIL109C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0090110"(COPII-coated vesicle cargo loading)|interpro:IPR006895(Zinc finger, Sec23/Sec24-type)|interpro:IPR006896(Sec23/Sec24 trunk region)|interpro:IPR006900(Sec23/Sec24 helical region)|interpro:IPR007123(Gelsolin region)|interpro:IPR012990(Sec23/Sec24 beta-sandwich)|interpro:IPR029006|interpro:IPR036174|interpro:IPR036175|interpro:IPR036180|go:"GO:0000149"(SNARE binding)|go:"GO:0000329"(fungal-type vacuole membrane)|interpro:IPR036465|interpro:IPR041742|rcsb pdb:1M2V|rcsb pdb:1PCX|rcsb pdb:1PD0|rcsb pdb:1PD1|rcsb pdb:4BZI|rcsb pdb:6GNI|rcsb pdb:6ZGA|reactome:R-SCE-204005|reactome:R-SCE-5694530|reactome:R-SCE-983170|go:"GO:0005048"(signal sequence binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|sgd:S000001371|dip:DIP-2233N|mint:P40482|sgd:YIL109C(identity)	ensembl:ENSG00000151790(gene)|ensembl:ENSG00000262635(gene)|ensembl:ENST00000536354(transcript)|ensembl:ENST00000573403(transcript)|go:"GO:0004833"(tryptophan 2,3-dioxygenase activity)|go:"GO:0005829"(cytosol)|go:"GO:0016597"(amino acid binding)|go:"GO:0019441"(tryptophan catabolic process to kynurenine)|go:"GO:0019442"(tryptophan catabolic process to acetyl-CoA)|go:"GO:0019825"(oxygen binding)|go:"GO:0020037"(heme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051289"(protein homotetramerization)|go:"GO:1904842"(response to nitroglycerin)|interpro:IPR004981(Tryptophan 2,3-dioxygenase)|interpro:IPR037217|mint:P48775|rcsb pdb:4PW8|rcsb pdb:5TI9|rcsb pdb:5TIA|rcsb pdb:6A4I|rcsb pdb:6PYY|rcsb pdb:6PYZ|rcsb pdb:6UD5|rcsb pdb:6VBN|reactome:R-HSA-71240|refseq:NP_005642.1|entrezgene/locuslink:6999(identity)	-	crc64:35E2BDD24CC75899	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:e7ekVFzZJMZvfRUZ9Q2jDQ/hvs0559292	rogid:S+cyc710I52nIFQWgKhXFul9QZw9606	intact-crc:7DDD3CEDBA82592E|rigid:e1ekJe+ubt+dKlyu1GO5jSgwoVw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O76081-6	uniprotkb:P40482	intact:EBI-10178530|ensembl:ENSP00000276500	intact:EBI-16592|ensemblfungi:YIL109C|uniprotkb:D6VVH8	psi-mi:o76081-6(display_long)|uniprotkb:RGS20(gene name)|psi-mi:RGS20(display_short)|uniprotkb:Gz-selective GTPase-activating protein(gene name synonym)|uniprotkb:RGSZ1(gene name synonym)|uniprotkb:Regulator of G-protein signaling Z1(gene name synonym)|uniprotkb:Regulator of Gz-selective protein signaling 1(gene name synonym)|uniprotkb:ZGAP1(gene name synonym)	psi-mi:sec24_yeast(display_long)|uniprotkb:SEC24(gene name)|psi-mi:SEC24(display_short)|uniprotkb:Abnormal nuclear morphology 1(gene name synonym)|uniprotkb:ANU1(gene name synonym)|uniprotkb:YIL109C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11541797|imex:IM-24995-2049	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-1052678(isoform-parent)|uniprotkb:O76081-6(isoform-parent)|ensembl:ENSG00000147509(gene)|ensembl:ENST00000276500(transcript)|entrezgene/locuslink:8601(identity)	refseq:NP_012157.3|ensemblfungi:YIL109C(gene)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016236"(macroautophagy)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0070971"(endoplasmic reticulum exit site)|ensemblfungi:YIL109C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0090110"(COPII-coated vesicle cargo loading)|interpro:IPR006895(Zinc finger, Sec23/Sec24-type)|interpro:IPR006896(Sec23/Sec24 trunk region)|interpro:IPR006900(Sec23/Sec24 helical region)|interpro:IPR007123(Gelsolin region)|interpro:IPR012990(Sec23/Sec24 beta-sandwich)|interpro:IPR029006|interpro:IPR036174|interpro:IPR036175|interpro:IPR036180|go:"GO:0000149"(SNARE binding)|go:"GO:0000329"(fungal-type vacuole membrane)|interpro:IPR036465|interpro:IPR041742|rcsb pdb:1M2V|rcsb pdb:1PCX|rcsb pdb:1PD0|rcsb pdb:1PD1|rcsb pdb:4BZI|rcsb pdb:6GNI|rcsb pdb:6ZGA|reactome:R-SCE-204005|reactome:R-SCE-5694530|reactome:R-SCE-983170|go:"GO:0005048"(signal sequence binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|sgd:S000001371|dip:DIP-2233N|mint:P40482|sgd:YIL109C(identity)	-	-	crc64:35E2BDD24CC75899	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:5ddWx+4uSAxIhugOqlfdCIOD8sM9606	rogid:e7ekVFzZJMZvfRUZ9Q2jDQ/hvs0559292	intact-crc:24D33246B8D2B4A2|rigid:YhPTliygjtLXzPH62nXn2agvctI	false	sufficient binding region:25-241	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40507	uniprotkb:P15622-3	intact:EBI-25083|uniprotkb:D6VVK5|ensemblfungi:YIL079C	intact:EBI-10177272|ensembl:ENSP00000393442	psi-mi:air1_yeast(display_long)|uniprotkb:Arginine methyltransferase-interacting RING finger protein 1(gene name synonym)|uniprotkb:AIR1(gene name)|psi-mi:AIR1(display_short)|uniprotkb:YIL079C(locus name)	psi-mi:p15622-3(display_long)|uniprotkb:ZNF647(gene name synonym)|uniprotkb:Zinc finger protein 647(gene name synonym)|uniprotkb:ZNF250(gene name)|psi-mi:ZNF250(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11541935|imex:IM-24995-2064	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012186.1|sgd:S000001341|mint:P40507|dip:DIP-2700N|ensemblfungi:YIL079C(gene)|ensemblfungi:YIL079C_mRNA(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031499"(TRAMP complex)|go:"GO:0043629"(ncRNA polyadenylation)|go:"GO:0071031"(nuclear mRNA surveillance of mRNA 3'-end processing)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071036"(nuclear polyadenylation-dependent snoRNA catabolic process)|go:"GO:0071037"(nuclear polyadenylation-dependent snRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071039"(nuclear polyadenylation-dependent CUT catabolic process)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR016713("Poly(A) polymerase complex, Air1/2")|interpro:IPR036875|sgd:YIL079C(identity)	ensembl:ENSG00000196150(gene)|ensembl:ENST00000417550(transcript)|intact:EBI-739678(isoform-parent)|uniprotkb:P15622-3(isoform-parent)|entrezgene/locuslink:58500(identity)	-	crc64:3CA920FA1204EC9C	isoform-comment:No experimental confirmation available.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:myPxXwP+mJgvoh50PLYk2Q3GMh4559292	rogid:4AVjeOREEATULMJWtdeZt7rhi889606	intact-crc:D67F1B70CDE1EFD9|rigid:Dk5IFw8zoK+HyqUvFGaAk0kqfz4	false	-	sufficient binding region:46-555	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P07910-2	uniprotkb:P40507	intact:EBI-5280084|ensembl:ENSP00000442816|ensembl:ENSP00000450544|ensembl:ENSP00000450725|ensembl:ENSP00000451176	intact:EBI-25083|uniprotkb:D6VVK5|ensemblfungi:YIL079C	psi-mi:p07910-2(display_long)|uniprotkb:HNRNPC(gene name)|psi-mi:HNRNPC(display_short)|uniprotkb:HNRPC(gene name synonym)	psi-mi:air1_yeast(display_long)|uniprotkb:Arginine methyltransferase-interacting RING finger protein 1(gene name synonym)|uniprotkb:AIR1(gene name)|psi-mi:AIR1(display_short)|uniprotkb:YIL079C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11541925|imex:IM-24995-2063	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:P07910-2(isoform-parent)|intact:EBI-357966(isoform-parent)|ensembl:ENSG00000092199(gene)|ensembl:ENST00000430246(transcript)|ensembl:ENST00000553300(transcript)|ensembl:ENST00000554969(transcript)|ensembl:ENST00000556897(transcript)|entrezgene/locuslink:3183(identity)	refseq:NP_012186.1|sgd:S000001341|mint:P40507|dip:DIP-2700N|ensemblfungi:YIL079C(gene)|ensemblfungi:YIL079C_mRNA(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031499"(TRAMP complex)|go:"GO:0043629"(ncRNA polyadenylation)|go:"GO:0071031"(nuclear mRNA surveillance of mRNA 3'-end processing)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071036"(nuclear polyadenylation-dependent snoRNA catabolic process)|go:"GO:0071037"(nuclear polyadenylation-dependent snRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071039"(nuclear polyadenylation-dependent CUT catabolic process)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR016713("Poly(A) polymerase complex, Air1/2")|interpro:IPR036875|sgd:YIL079C(identity)	-	isoform-comment:Contains a phosphoserine at position 107. Contains a phosphoserine at position 108.	crc64:3CA920FA1204EC9C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:r7AhGozE3aHdynLr8DrXPRtOuyI9606	rogid:myPxXwP+mJgvoh50PLYk2Q3GMh4559292	intact-crc:8D0C9E26B4CFBC6C|rigid:Sc9prlxF38fvgxdgRooc5Z7hWGM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O14641	uniprotkb:P40507	intact:EBI-740850|ensembl:ENSP00000005340|uniprotkb:Q53XM0|uniprotkb:D3DTN3	intact:EBI-25083|uniprotkb:D6VVK5|ensemblfungi:YIL079C	psi-mi:dvl2_human(display_long)|uniprotkb:DSH homolog 2(gene name synonym)|uniprotkb:DVL2(gene name)|psi-mi:DVL2(display_short)	psi-mi:air1_yeast(display_long)|uniprotkb:Arginine methyltransferase-interacting RING finger protein 1(gene name synonym)|uniprotkb:AIR1(gene name)|psi-mi:AIR1(display_short)|uniprotkb:YIL079C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11541916|imex:IM-24995-2062	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004413.1|ensembl:ENSG00000004975(gene)|ensembl:ENST00000005340(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005109"(frizzled binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0007507"(heart development)|go:"GO:0016235"(aggresome)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044340"(canonical Wnt signaling pathway involved in regulation of cell proliferation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0150012"(positive regulation of neuron projection arborization)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008341(Dishevelled-2 region)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:O14641|rcsb pdb:2REY|rcsb pdb:3CBX|rcsb pdb:3CBY|rcsb pdb:3CBZ|rcsb pdb:3CC0|rcsb pdb:4WIP|rcsb pdb:5LNP|rcsb pdb:5SUY|rcsb pdb:5SUZ|rcsb pdb:6IW3|rcsb pdb:6JCK|reactome:R-HSA-201681|reactome:R-HSA-201688|reactome:R-HSA-2028269|reactome:R-HSA-4086400|reactome:R-HSA-4608870|reactome:R-HSA-4641258|reactome:R-HSA-4641262|reactome:R-HSA-5099900|reactome:R-HSA-5368598|reactome:R-HSA-5663220|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9673324|ensembl:ENSP00000005340|dip:DIP-34433N|entrezgene/locuslink:1856(identity)	refseq:NP_012186.1|sgd:S000001341|mint:P40507|dip:DIP-2700N|ensemblfungi:YIL079C(gene)|ensemblfungi:YIL079C_mRNA(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031499"(TRAMP complex)|go:"GO:0043629"(ncRNA polyadenylation)|go:"GO:0071031"(nuclear mRNA surveillance of mRNA 3'-end processing)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071036"(nuclear polyadenylation-dependent snoRNA catabolic process)|go:"GO:0071037"(nuclear polyadenylation-dependent snRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071039"(nuclear polyadenylation-dependent CUT catabolic process)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR016713("Poly(A) polymerase complex, Air1/2")|interpro:IPR036875|sgd:YIL079C(identity)	-	-	crc64:3CA920FA1204EC9C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:2Vdc8oRnT4Mz/j+EXQXrL3AszOc9606	rogid:myPxXwP+mJgvoh50PLYk2Q3GMh4559292	intact-crc:A17A5B56868E64C7|rigid:57oxXwgEOJrXbemx21HDveUyELo	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40507	uniprotkb:Q8N5R6	intact:EBI-25083|uniprotkb:D6VVK5|ensemblfungi:YIL079C	intact:EBI-740841|intact:EBI-953781|uniprotkb:B3KQ49|uniprotkb:A8K3U4|uniprotkb:A8MPQ6|uniprotkb:A8MV61|uniprotkb:A8MVU9|uniprotkb:Q9H5Q6|uniprotkb:Q8TAX6|intact:EBI-2320546|intact:EBI-11522976	psi-mi:air1_yeast(display_long)|uniprotkb:Arginine methyltransferase-interacting RING finger protein 1(gene name synonym)|uniprotkb:AIR1(gene name)|psi-mi:AIR1(display_short)|uniprotkb:YIL079C(locus name)	psi-mi:ccd33_human(display_long)|uniprotkb:CCDC33(gene name)|psi-mi:CCDC33(display_short)|uniprotkb:Cancer/testis antigen 61(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11541907|imex:IM-24995-2061	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012186.1|sgd:S000001341|mint:P40507|dip:DIP-2700N|ensemblfungi:YIL079C(gene)|ensemblfungi:YIL079C_mRNA(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031499"(TRAMP complex)|go:"GO:0043629"(ncRNA polyadenylation)|go:"GO:0071031"(nuclear mRNA surveillance of mRNA 3'-end processing)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071036"(nuclear polyadenylation-dependent snoRNA catabolic process)|go:"GO:0071037"(nuclear polyadenylation-dependent snRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071039"(nuclear polyadenylation-dependent CUT catabolic process)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR016713("Poly(A) polymerase complex, Air1/2")|interpro:IPR036875|sgd:YIL079C(identity)	refseq:NP_079331.3|interpro:IPR000008(C2 calcium-dependent membrane targeting)|go:"GO:0005777"(peroxisome)|refseq:NP_001274110.1|refseq:NP_877592.2|mint:Q8N5R6|interpro:IPR035892|interpro:IPR039889|entrezgene/locuslink:80125(identity)	-	crc64:3CA920FA1204EC9C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2021/11/30	rogid:myPxXwP+mJgvoh50PLYk2Q3GMh4559292	rogid:eEIn7pQyfdHWx8TeLJpYy0i/gww9606	intact-crc:587E1DFD395D4844|rigid:cim1x7HrbAQekz/HjixosQzWvzM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96BA8	uniprotkb:P40501	intact:EBI-6942903|ensembl:ENSP00000481956|intact:MINT-268046|intact:MINT-8162577|uniprotkb:Q8N2D5|uniprotkb:Q96CP0	intact:EBI-11531370|uniprotkb:D6VVJ9|ensemblfungi:YIL088C	psi-mi:cr3l1_human(display_long)|uniprotkb:CREB3L1(gene name)|psi-mi:CREB3L1(display_short)|uniprotkb:OASIS(gene name synonym)|uniprotkb:PSEC0238(orf name)|uniprotkb:Old astrocyte specifically-induced substance(gene name synonym)	psi-mi:avt7_yeast(display_long)|uniprotkb:AVT7(gene name)|psi-mi:AVT7(display_short)|uniprotkb:YIL088C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11541898|imex:IM-24995-2060	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157613(gene)|ensembl:ENST00000621158(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0070278"(extracellular matrix constituent secretion)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029805|mint:Q96BA8|reactome:R-HSA-8874211|refseq:NP_443086.1|entrezgene/locuslink:90993(identity)	refseq:NP_012178.1|sgd:S000001350|ensemblfungi:YIL088C(gene)|ensemblfungi:YIL088C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0003333"(amino acid transmembrane transport)|go:"GO:0005290"(L-histidine transmembrane transporter activity)|go:"GO:0005302"(L-tyrosine transmembrane transporter activity)|go:"GO:0005313"(L-glutamate transmembrane transporter activity)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006865"(amino acid transport)|go:"GO:0015171"(amino acid transmembrane transporter activity)|go:"GO:0015189"(L-lysine transmembrane transporter activity)|go:"GO:0015194"(L-serine transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0043937"(regulation of sporulation)|go:"GO:0061459"(L-arginine transmembrane transporter activity)|interpro:IPR013057(Amino acid transporter, transmembrane)|dip:DIP-7299N|sgd:YIL088C(identity)	-	comment:mint|function:"Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE"	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/03/16	rogid:sMWUFmBeBBCO+T0Y2CuB/un1lBg9606	rogid:h/wTkn7UHQvjASI16kH6WV6wtC8559292	intact-crc:930645207B73D39D|rigid:w+mz918KyG6WmrOmroEz0EEF4YQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9Y2D8	uniprotkb:P40498	intact:EBI-2212028|uniprotkb:B4DFE3|uniprotkb:J3KR02|uniprotkb:A8K8W0|uniprotkb:D3DT13|uniprotkb:Q6P2P8|uniprotkb:Q6ULS1|uniprotkb:Q7L168|uniprotkb:Q9UIX0|intact:EBI-10964529|ensembl:ENSP00000340279	intact:EBI-25113|uniprotkb:D6VVJ6|ensemblfungi:YIL091C	psi-mi:adip_human(display_long)|uniprotkb:SSX2IP(gene name)|psi-mi:SSX2IP(display_short)|uniprotkb:KIAA0923(gene name synonym)|uniprotkb:Afadin DIL domain-interacting protein(gene name synonym)|uniprotkb:SSX2-interacting protein(gene name synonym)	psi-mi:utp25_yeast(display_long)|uniprotkb:YIL091C(locus name)|uniprotkb:UTP25(gene name)|psi-mi:UTP25(display_short)|uniprotkb:U three protein 25(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11541889|imex:IM-24995-2059	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011538912.1|refseq:NP_001159765.1|refseq:NP_001159766.1|refseq:NP_001159767.1|refseq:NP_001159889.1|refseq:NP_054740.3|refseq:XP_005270484.1|refseq:XP_005270485.1|refseq:XP_006710394.1|refseq:XP_016855723.1|ensembl:ENSG00000117155(gene)|ensembl:ENST00000342203(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005912"(adherens junction)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031252"(cell leading edge)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0035735"(intraciliary transport involved in cilium assembly)|go:"GO:0036064"(ciliary basal body)|go:"GO:0060271"(cilium assembly)|go:"GO:2000145"(regulation of cell motility)|interpro:IPR021622|mint:Q9Y2D8|entrezgene/locuslink:117178(identity)	refseq:NP_012175.1|sgd:S000001353|mint:P40498|dip:DIP-5629N|ensemblfungi:YIL091C(gene)|ensemblfungi:YIL091C_mRNA(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0019843"(rRNA binding)|go:"GO:0032040"(small-subunit processome)|go:"GO:0034511"(U3 snoRNA binding)|go:"GO:0042274"(ribosomal small subunit biogenesis)|interpro:IPR010678(Protein of unknown function DUF1253)|interpro:IPR027417|reactome:R-SCE-6791226|sgd:YIL091C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:E0VeMRF9SrpQKSJFP01XEbMjeF89606	rogid:9OTjSNDfUXoxYLjdDlhobs3AKa8559292	intact-crc:0325BED928B68E0E|rigid:0S6RBVnmIXiApeCgZprKXozyULk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40491	uniprotkb:O95273	intact:EBI-25141|uniprotkb:D6VVI9|ensemblfungi:YIL098C	intact:EBI-748961|uniprotkb:A8K3Q0|uniprotkb:A8K3U2|uniprotkb:Q6ZQN9|uniprotkb:Q7Z519|uniprotkb:Q8NBS7|uniprotkb:Q8NBY2|uniprotkb:Q9NS19|uniprotkb:Q9NYH3|uniprotkb:Q9UHX9|ensembl:ENSP00000300213	psi-mi:fmc1_yeast(display_long)|uniprotkb:Formation of mitochondrial complexes protein 1(gene name synonym)|uniprotkb:YIL098C(locus name)|uniprotkb:FMC1(gene name)|psi-mi:FMC1(display_short)	psi-mi:ccdb1_human(display_long)|uniprotkb:Grap2 and cyclin-D-interacting protein(gene name synonym)|uniprotkb:Human homolog of Maid(gene name synonym)|uniprotkb:CCNDBP1(gene name)|psi-mi:CCNDBP1(display_short)|uniprotkb:DIP1(gene name synonym)|uniprotkb:GCIP(gene name synonym)|uniprotkb:HHM(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11541880|imex:IM-24995-2058	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000001360|refseq:NP_012168.3|mint:P40491|dip:DIP-5652N|ensemblfungi:YIL098C(gene)|ensemblfungi:YIL098C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0016236"(macroautophagy)|go:"GO:0033615"(mitochondrial proton-transporting ATP synthase complex assembly)|interpro:IPR039196|sgd:YIL098C(identity)	refseq:NP_036274.3|ensembl:ENSG00000166946(gene)|ensembl:ENST00000300213(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0016604"(nuclear body)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR026907|mint:O95273|rcsb pdb:3AY5|entrezgene/locuslink:23582(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:lGt1inZN/0++e/TWYR1mZnMBG2o559292	rogid:Vi9aoFc+Mov6P3X6KGmsTxXqxvM9606	intact-crc:6631A6BAC947FBD0|rigid:xf9fPRteokFBvM531dSYRH/F6jU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40487	uniprotkb:Q9BQC3	intact:EBI-25162|uniprotkb:D6VVI4|ensemblfungi:YIL103W	intact:EBI-10237931|uniprotkb:O60623|uniprotkb:B4DNI8|uniprotkb:B2RDE3|uniprotkb:A8MVC9|ensembl:ENSP00000255108	psi-mi:dph1_yeast(display_long)|uniprotkb:DPH1(gene name)|psi-mi:DPH1(display_short)|uniprotkb:Diphthamide biosynthesis protein 1(gene name synonym)|uniprotkb:Diphtheria toxin resistance protein 1(gene name synonym)|uniprotkb:"S-adenosyl-L-methionine:L-histidine 3-amino-3-carboxypropyltransferase 1"(gene name synonym)|uniprotkb:YIL103W(locus name)	psi-mi:dph2_human(display_long)|uniprotkb:Diphthamide biosynthesis protein 2(gene name synonym)|uniprotkb:Diphtheria toxin resistance protein 2(gene name synonym)|uniprotkb:DPH2(gene name)|psi-mi:DPH2(display_short)|uniprotkb:DPH2L2(gene name synonym)|uniprotkb:"S-adenosyl-L-methionine:L-histidine 3-amino-3-carboxypropyltransferase 2"(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11541871|imex:IM-24995-2057	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012163.1|sgd:S000001365|mint:P40487|dip:DIP-5653N|ensemblfungi:YIL103W(gene)|ensemblfungi:YIL103W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0017183"(peptidyl-diphthamide biosynthetic process from peptidyl-histidine)|go:"GO:0090560"("2-(3-amino-3-carboxypropyl)histidine synthase activity")|interpro:IPR016435(Diphthamide synthesis, DHP1)|interpro:IPR035435|interpro:IPR042263|interpro:IPR042264|interpro:IPR042265|reactome:R-SCE-5358493|sgd:YIL103W(identity)	refseq:NP_001306095.1|refseq:NP_001306098.1|refseq:NP_001034678.1|refseq:NP_001375.2|ensembl:ENSG00000132768(gene)|ensembl:ENST00000255108(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0017183"(peptidyl-diphthamide biosynthetic process from peptidyl-histidine)|go:"GO:0090560"("2-(3-amino-3-carboxypropyl)histidine synthase activity")|interpro:IPR010014(Diphthamide synthesis, DHP2)|interpro:IPR016435(Diphthamide synthesis, DHP1)|interpro:IPR042263|interpro:IPR042265|reactome:R-HSA-5358493|entrezgene/locuslink:1802(identity)	-	crc64:22E93852E03C6722	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:zk1Esuvz7u5GtymKbFzfv+PFAPQ559292	rogid:/Z9UhAa8qkHe3rPFS3OPfiJ4RFM9606	intact-crc:D1BA37FDFA9C7760|rigid:2KWZtj6bcqiQy22WKS9+Eu5pQSw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40554	intact:EBI-11531492	intact:EBI-24940|uniprotkb:D6VVS2|ensemblfungi:YIL008W	-	psi-mi:urm1_yeast(display_long)|uniprotkb:YIL008W(locus name)|uniprotkb:URM1(gene name)|psi-mi:URM1(display_short)	psi-mi:znf3(display_short)|psi-mi:EBI-11531492(display_long)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11542020|imex:IM-24995-2073	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000001270|refseq:NP_012258.3|dip:DIP-1894N|ensemblfungi:YIL008W(gene)|ensemblfungi:YIL008W_mRNA(transcript)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0002143"(tRNA wobble position uridine thiolation)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007114"(cell budding)|go:"GO:0031386"(protein tag)|go:"GO:0032447"(protein urmylation)|go:"GO:0034227"(tRNA thio-modification)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0097163"(sulfur carrier activity)|interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|interpro:IPR015221(Ubiquitin related modifier 1)|interpro:IPR016155(Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp)|rcsb pdb:2AX5|rcsb pdb:2PKO|rcsb pdb:2QJL|sgd:YIL008W(identity)	entrezgene/locuslink:7551(identity)	-	crc64:A15356D6C1B6B5BC	no-uniprot-update:	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:JFW+GAegUnn1FQ2++OlVr9IbgBA559292	rogid:eSPiEBOxNojLEOXLwp/UY9zTIwo9606	intact-crc:A441873E14461E9D|rigid:YY/IMmZxhjIgmlUfYuA9YevnKM8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96BA8	uniprotkb:P40533	intact:EBI-6942903|ensembl:ENSP00000481956|intact:MINT-268046|intact:MINT-8162577|uniprotkb:Q8N2D5|uniprotkb:Q96CP0	intact:EBI-24998|uniprotkb:D6VVP3|ensemblfungi:YIL039W	psi-mi:cr3l1_human(display_long)|uniprotkb:CREB3L1(gene name)|psi-mi:CREB3L1(display_short)|uniprotkb:OASIS(gene name synonym)|uniprotkb:PSEC0238(orf name)|uniprotkb:Old astrocyte specifically-induced substance(gene name synonym)	psi-mi:ted1_yeast(display_long)|uniprotkb:TED1(gene name)|psi-mi:TED1(display_short)|uniprotkb:Trafficking of EMP24/ERV25-dependent cargo disrupted protein 1(gene name synonym)|uniprotkb:YIL039W(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11542011|imex:IM-24995-2072	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157613(gene)|ensembl:ENST00000621158(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0070278"(extracellular matrix constituent secretion)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029805|mint:Q96BA8|reactome:R-HSA-8874211|refseq:NP_443086.1|entrezgene/locuslink:90993(identity)	refseq:NP_012225.1|sgd:S000001301|mint:P40533|dip:DIP-4575N|ensemblfungi:YIL039W(gene)|ensemblfungi:YIL039W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006506"(GPI anchor biosynthetic process)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016787"(hydrolase activity)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR029052|interpro:IPR033307|interpro:IPR033308|sgd:YIL039W(identity)	-	comment:mint|function:"Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE"	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:sMWUFmBeBBCO+T0Y2CuB/un1lBg9606	rogid:/O/7xxWpFv7PwN+keOZRqQQPoFw559292	intact-crc:A6BEEE346895E42E|rigid:dPR79iA9fNxkT0y99IcuJJhC1RI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8N6L0	uniprotkb:P40533	intact:EBI-749265|uniprotkb:Q96MC3|ensembl:ENSP00000404220	intact:EBI-24998|uniprotkb:D6VVP3|ensemblfungi:YIL039W	psi-mi:kash5_human(display_long)|uniprotkb:KASH5(gene name)|psi-mi:KASH5(display_short)|uniprotkb:CCDC155(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 155(gene name synonym)|uniprotkb:KASH domain-containing protein 5(gene name synonym)	psi-mi:ted1_yeast(display_long)|uniprotkb:TED1(gene name)|psi-mi:TED1(display_short)|uniprotkb:Trafficking of EMP24/ERV25-dependent cargo disrupted protein 1(gene name synonym)|uniprotkb:YIL039W(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11542002|imex:IM-24995-2071	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_653289.3|ensembl:ENSG00000161609(gene)|ensembl:ENST00000447857(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034397"(telomere localization)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051225"(spindle assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0090172"(microtubule cytoskeleton organization involved in homologous chromosome segregation)|go:"GO:0090220"(chromosome localization to nuclear envelope involved in homologous chromosome segregation)|go:"GO:0090619"(meiotic spindle pole)|interpro:IPR011992(EF-Hand type)|interpro:IPR028168|interpro:IPR028170|interpro:IPR039508|mint:Q8N6L0|rcsb pdb:6R2I|rcsb pdb:6WMF|entrezgene/locuslink:147872(identity)	refseq:NP_012225.1|sgd:S000001301|mint:P40533|dip:DIP-4575N|ensemblfungi:YIL039W(gene)|ensemblfungi:YIL039W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006506"(GPI anchor biosynthetic process)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016787"(hydrolase activity)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR029052|interpro:IPR033307|interpro:IPR033308|sgd:YIL039W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Wl9L7AcvDHCZuKjYLn8QgGIbZTc9606	rogid:/O/7xxWpFv7PwN+keOZRqQQPoFw559292	intact-crc:FA5618E79DDCA9C6|rigid:atuyt74ltwZk0Cp4nQBel7EZ7BE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40507	uniprotkb:Q96IK5	intact:EBI-25083|uniprotkb:D6VVK5|ensemblfungi:YIL079C	intact:EBI-2548508|ensembl:ENSP00000282570|uniprotkb:Q9H826|uniprotkb:Q9H8V7|uniprotkb:Q9H927	psi-mi:air1_yeast(display_long)|uniprotkb:Arginine methyltransferase-interacting RING finger protein 1(gene name synonym)|uniprotkb:AIR1(gene name)|psi-mi:AIR1(display_short)|uniprotkb:YIL079C(locus name)	psi-mi:gmcl1_human(display_long)|uniprotkb:GMCL1(gene name)|psi-mi:GMCL1(display_short)|uniprotkb:GCL(gene name synonym)|uniprotkb:BTBD13(gene name synonym)|uniprotkb:SPATA29(gene name synonym)|uniprotkb:Spermatogenesis-associated protein 29(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11541993|imex:IM-24995-2070	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012186.1|sgd:S000001341|mint:P40507|dip:DIP-2700N|ensemblfungi:YIL079C(gene)|ensemblfungi:YIL079C_mRNA(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031499"(TRAMP complex)|go:"GO:0043629"(ncRNA polyadenylation)|go:"GO:0071031"(nuclear mRNA surveillance of mRNA 3'-end processing)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071036"(nuclear polyadenylation-dependent snoRNA catabolic process)|go:"GO:0071037"(nuclear polyadenylation-dependent snRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071039"(nuclear polyadenylation-dependent CUT catabolic process)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR016713("Poly(A) polymerase complex, Air1/2")|interpro:IPR036875|sgd:YIL079C(identity)	ensembl:ENSG00000087338(gene)|ensembl:ENST00000282570(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0007281"(germ cell development)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016363"(nuclear matrix)|go:"GO:0042802"(identical protein binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR043380|refseq:NP_848526.1|entrezgene/locuslink:64395(identity)	-	crc64:3CA920FA1204EC9C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:myPxXwP+mJgvoh50PLYk2Q3GMh4559292	rogid:ED8yqySVu7BWxpw3DUSNBZSQWrk9606	intact-crc:7F54D9792A63B199|rigid:vdWOOQGg2EmQkl9dneCG+ZkcJBk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8WV44	uniprotkb:P40507	intact:EBI-725997|uniprotkb:Q5BKT0|uniprotkb:Q7L484|uniprotkb:Q96Q10|intact:EBI-1551110|uniprotkb:Q9BSL8|uniprotkb:B3KNJ6|uniprotkb:D3DWR9|ensembl:ENSP00000320869	intact:EBI-25083|uniprotkb:D6VVK5|ensemblfungi:YIL079C	psi-mi:tri41_human(display_long)|uniprotkb:TRIM41(gene name)|psi-mi:TRIM41(display_short)|uniprotkb:RINCK(gene name synonym)|uniprotkb:Tripartite motif-containing protein 41(gene name synonym)|uniprotkb:RING finger-interacting protein with C kinase(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM41(gene name synonym)	psi-mi:air1_yeast(display_long)|uniprotkb:Arginine methyltransferase-interacting RING finger protein 1(gene name synonym)|uniprotkb:AIR1(gene name)|psi-mi:AIR1(display_short)|uniprotkb:YIL079C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11541982|imex:IM-24995-2069	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_291027.3|refseq:NP_963921.1|ensembl:ENSG00000146063(gene)|ensembl:ENST00000315073(transcript)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0042802"(identical protein binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071225"(cellular response to muramyl dipeptide)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR042828|interpro:IPR043136|mint:Q8WV44|rcsb pdb:2EGM|reactome:R-HSA-983168|entrezgene/locuslink:90933(identity)	refseq:NP_012186.1|sgd:S000001341|mint:P40507|dip:DIP-2700N|ensemblfungi:YIL079C(gene)|ensemblfungi:YIL079C_mRNA(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031499"(TRAMP complex)|go:"GO:0043629"(ncRNA polyadenylation)|go:"GO:0071031"(nuclear mRNA surveillance of mRNA 3'-end processing)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071036"(nuclear polyadenylation-dependent snoRNA catabolic process)|go:"GO:0071037"(nuclear polyadenylation-dependent snRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071039"(nuclear polyadenylation-dependent CUT catabolic process)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR016713("Poly(A) polymerase complex, Air1/2")|interpro:IPR036875|sgd:YIL079C(identity)	-	-	crc64:3CA920FA1204EC9C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:BVqf0OHXPGsYe8F66mHzvD4XQ549606	rogid:myPxXwP+mJgvoh50PLYk2Q3GMh4559292	intact-crc:35081C48F68486F8|rigid:Yz4r4Nxyaosre+oy+CJRJxVqaRc	false	sufficient binding region:86-630	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40507	uniprotkb:Q8WTR7	intact:EBI-25083|uniprotkb:D6VVK5|ensemblfungi:YIL079C	intact:EBI-751409|uniprotkb:Q9ULS9|uniprotkb:Q9Y4Q7|uniprotkb:A8K8T7|intact:EBI-28978826|ensembl:ENSP00000270617|ensembl:ENSP00000375697|ensembl:ENSP00000472808	psi-mi:air1_yeast(display_long)|uniprotkb:Arginine methyltransferase-interacting RING finger protein 1(gene name synonym)|uniprotkb:AIR1(gene name)|psi-mi:AIR1(display_short)|uniprotkb:YIL079C(locus name)	psi-mi:zn473_human(display_long)|uniprotkb:Zinc finger protein 100 homolog(gene name synonym)|uniprotkb:ZNF473(gene name)|psi-mi:ZNF473(display_short)|uniprotkb:KIAA1141(gene name synonym)|uniprotkb:ZFP100(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11541973|imex:IM-24995-2068	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012186.1|sgd:S000001341|mint:P40507|dip:DIP-2700N|ensemblfungi:YIL079C(gene)|ensemblfungi:YIL079C_mRNA(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031499"(TRAMP complex)|go:"GO:0043629"(ncRNA polyadenylation)|go:"GO:0071031"(nuclear mRNA surveillance of mRNA 3'-end processing)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071036"(nuclear polyadenylation-dependent snoRNA catabolic process)|go:"GO:0071037"(nuclear polyadenylation-dependent snRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071039"(nuclear polyadenylation-dependent CUT catabolic process)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR016713("Poly(A) polymerase complex, Air1/2")|interpro:IPR036875|sgd:YIL079C(identity)	refseq:NP_001006657.1|refseq:NP_056243.1|ensembl:ENSP00000270617|ensembl:ENSP00000375697|ensembl:ENSP00000472808|refseq:NP_001295353.1|ensembl:ENSG00000142528(gene)|ensembl:ENST00000270617(transcript)|ensembl:ENST00000391821(transcript)|ensembl:ENST00000595661(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006398"(mRNA 3'-end processing by stem-loop binding and cleavage)|go:"GO:0015030"(Cajal body)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|rcsb pdb:2EMB|rcsb pdb:2EMC|rcsb pdb:2EME|rcsb pdb:2EOU|rcsb pdb:2EOX|rcsb pdb:2EOY|rcsb pdb:2EOZ|rcsb pdb:2YRH|rcsb pdb:2YRJ|rcsb pdb:2YSV|rcsb pdb:2YTD|rcsb pdb:2YTE|rcsb pdb:2YTT|rcsb pdb:2YU5|reactome:R-HSA-111367|reactome:R-HSA-212436|reactome:R-HSA-73856|reactome:R-HSA-77588|entrezgene/locuslink:25888(identity)	-	crc64:3CA920FA1204EC9C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:myPxXwP+mJgvoh50PLYk2Q3GMh4559292	rogid:Tm+mqhJ8JVqLYFprsek+VYhcnOI9606	intact-crc:CC91A326FE8F08F7|rigid:mIzg72Yp2WZuS2yd/ygpPJ4s6Xg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40507	uniprotkb:Q8NHQ1	intact:EBI-25083|uniprotkb:D6VVK5|ensemblfungi:YIL079C	intact:EBI-739624|ensembl:ENSP00000264982|ensembl:ENSP00000419231|uniprotkb:Q96B31|uniprotkb:Q9H2C3|uniprotkb:Q9H2Z1|uniprotkb:Q9H940|uniprotkb:D3DNE9|uniprotkb:B7Z5I8|uniprotkb:B7Z7E8|uniprotkb:F5GZX8	psi-mi:air1_yeast(display_long)|uniprotkb:Arginine methyltransferase-interacting RING finger protein 1(gene name synonym)|uniprotkb:AIR1(gene name)|psi-mi:AIR1(display_short)|uniprotkb:YIL079C(locus name)	psi-mi:cep70_human(display_long)|uniprotkb:CEP70(gene name)|psi-mi:CEP70(display_short)|uniprotkb:BITE(gene name synonym)|uniprotkb:p10-binding protein(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11541964|imex:IM-24995-2067	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012186.1|sgd:S000001341|mint:P40507|dip:DIP-2700N|ensemblfungi:YIL079C(gene)|ensemblfungi:YIL079C_mRNA(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031499"(TRAMP complex)|go:"GO:0043629"(ncRNA polyadenylation)|go:"GO:0071031"(nuclear mRNA surveillance of mRNA 3'-end processing)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071036"(nuclear polyadenylation-dependent snoRNA catabolic process)|go:"GO:0071037"(nuclear polyadenylation-dependent snRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071039"(nuclear polyadenylation-dependent CUT catabolic process)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR016713("Poly(A) polymerase complex, Air1/2")|interpro:IPR036875|sgd:YIL079C(identity)	ensembl:ENSG00000114107(gene)|ensembl:ENST00000264982(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|interpro:IPR019734|interpro:IPR037692|mint:Q8NHQ1|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|ensembl:ENST00000484888(transcript)|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_077817.2|refseq:XP_016862764.1|refseq:NP_001275893.1|refseq:NP_001275894.1|refseq:NP_001275895.1|refseq:NP_001275896.1|refseq:NP_001307527.1|refseq:NP_001307529.1|entrezgene/locuslink:80321(identity)	-	crc64:3CA920FA1204EC9C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:myPxXwP+mJgvoh50PLYk2Q3GMh4559292	rogid:S4yveQWcvdVtAUX65gqrJ5Dv0Mc9606	intact-crc:AE4B2A0B6133794A|rigid:Hfww7CA+cje4UceaTeAirQcFeIg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40507	uniprotkb:Q5VWX1	intact:EBI-25083|uniprotkb:D6VVK5|ensemblfungi:YIL079C	intact:EBI-742808|uniprotkb:Q8TCZ4|uniprotkb:Q8N4I4|uniprotkb:A8K7M8|ensembl:ENSP00000281156	psi-mi:air1_yeast(display_long)|uniprotkb:Arginine methyltransferase-interacting RING finger protein 1(gene name synonym)|uniprotkb:AIR1(gene name)|psi-mi:AIR1(display_short)|uniprotkb:YIL079C(locus name)	psi-mi:khdr2_human(display_long)|uniprotkb:SLM1(gene name synonym)|uniprotkb:Sam68-like mammalian protein 1(gene name synonym)|uniprotkb:KHDRBS2(gene name)|psi-mi:KHDRBS2(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11541955|imex:IM-24995-2066	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012186.1|sgd:S000001341|mint:P40507|dip:DIP-2700N|ensemblfungi:YIL079C(gene)|ensemblfungi:YIL079C_mRNA(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031499"(TRAMP complex)|go:"GO:0043629"(ncRNA polyadenylation)|go:"GO:0071031"(nuclear mRNA surveillance of mRNA 3'-end processing)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071036"(nuclear polyadenylation-dependent snoRNA catabolic process)|go:"GO:0071037"(nuclear polyadenylation-dependent snRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071039"(nuclear polyadenylation-dependent CUT catabolic process)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR016713("Poly(A) polymerase complex, Air1/2")|interpro:IPR036875|sgd:YIL079C(identity)	refseq:NP_689901.2|ensembl:ENSG00000112232(gene)|ensembl:ENST00000281156(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008143"("poly(A) binding")|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0017124"(SH3 domain binding)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR032335|interpro:IPR032571|interpro:IPR036612|reactome:R-HSA-8849468|entrezgene/locuslink:202559(identity)	-	crc64:3CA920FA1204EC9C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:myPxXwP+mJgvoh50PLYk2Q3GMh4559292	rogid:IfFvZO2dIAo0Sdx+BUb5c8F7aQY9606	intact-crc:E6BE30F6DF5DD288|rigid:f2MNvYVqYGJ5XmyCqWbdv28GSI0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38159	uniprotkb:P40507	intact:EBI-743526|ensembl:ENSP00000359645|uniprotkb:Q5JQ67|uniprotkb:Q969R3|uniprotkb:D3DWH0|uniprotkb:E9PG86|uniprotkb:Q8N8Y7|uniprotkb:B4E3U4	intact:EBI-25083|uniprotkb:D6VVK5|ensemblfungi:YIL079C	psi-mi:rbmx_human(display_long)|uniprotkb:Glycoprotein p43(gene name synonym)|uniprotkb:RBMX(gene name)|psi-mi:RBMX(display_short)|uniprotkb:HNRPG(gene name synonym)|uniprotkb:RBMXP1(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein G(gene name synonym)	psi-mi:air1_yeast(display_long)|uniprotkb:Arginine methyltransferase-interacting RING finger protein 1(gene name synonym)|uniprotkb:AIR1(gene name)|psi-mi:AIR1(display_short)|uniprotkb:YIL079C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11541946|imex:IM-24995-2065	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000147274(gene)|ensembl:ENST00000320676(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000791"(euchromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0044530"(supraspliceosomal complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0006509"(membrane protein ectodomain proteolysis)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012604(RBM1CTR)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|mint:P38159|rcsb pdb:2MB0|rcsb pdb:2MKS|reactome:R-HSA-72163|reactome:R-HSA-72203|reactome:R-HSA-9013418|reactome:R-HSA-9013422|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273|refseq:NP_002130.2|refseq:NP_001158275.1|dip:DIP-34447N|entrezgene/locuslink:27316(identity)	refseq:NP_012186.1|sgd:S000001341|mint:P40507|dip:DIP-2700N|ensemblfungi:YIL079C(gene)|ensemblfungi:YIL079C_mRNA(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031499"(TRAMP complex)|go:"GO:0043629"(ncRNA polyadenylation)|go:"GO:0071031"(nuclear mRNA surveillance of mRNA 3'-end processing)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071036"(nuclear polyadenylation-dependent snoRNA catabolic process)|go:"GO:0071037"(nuclear polyadenylation-dependent snRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071039"(nuclear polyadenylation-dependent CUT catabolic process)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR016713("Poly(A) polymerase complex, Air1/2")|interpro:IPR036875|sgd:YIL079C(identity)	-	-	crc64:3CA920FA1204EC9C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:ocCkdy9PxjeVLUQf0tMVCEhFfO89606	rogid:myPxXwP+mJgvoh50PLYk2Q3GMh4559292	intact-crc:76E3320B5BB8BFEE|rigid:/BQgaVjBAPbAXp3cUMSPBC9hM5w	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40956	uniprotkb:O43251-3	intact:EBI-7968|uniprotkb:D6VTX2|ensemblfungi:YGL181W	intact:EBI-11531589|ensembl:ENSP00000262829|ensembl:ENSP00000485711	psi-mi:gts1_yeast(display_long)|uniprotkb:YGL181W(locus name)|uniprotkb:GTS1(gene name)|psi-mi:GTS1(display_short)|uniprotkb:LSR1(gene name synonym)|uniprotkb:Protein LSR1(gene name synonym)	psi-mi:o43251-3(display_long)|uniprotkb:RBFOX2(gene name)|psi-mi:RBFOX2(display_short)|uniprotkb:FOX2(gene name synonym)|uniprotkb:Fox-1 homolog B(gene name synonym)|uniprotkb:HRNBP2(gene name synonym)|uniprotkb:Hexaribonucleotide-binding protein 2(gene name synonym)|uniprotkb:RBM9(gene name synonym)|uniprotkb:RNA-binding motif protein 9(gene name synonym)|uniprotkb:RNA-binding protein 9(gene name synonym)|uniprotkb:RTA(gene name synonym)|uniprotkb:Repressor of tamoxifen transcriptional activity(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11542110|imex:IM-24995-2083	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011334.1|sgd:S000003149|mint:P40956|dip:DIP-2746N|ensemblfungi:YGL181W(gene)|ensemblfungi:YGL181W_mRNA(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0006897"(endocytosis)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010512"(negative regulation of phosphatidylinositol biosynthetic process)|go:"GO:0030479"(actin cortical patch)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR037278|interpro:IPR038508|sgd:YGL181W(identity)	intact:EBI-746056(isoform-parent)|ensembl:ENSG00000100320(gene)|ensembl:ENSG00000277564(gene)|ensembl:ENST00000262829(transcript)|ensembl:ENST00000631365(transcript)|uniprotkb:O43251-3(isoform-parent)|entrezgene/locuslink:23543(identity)	-	crc64:D687E3BF6B620795	isoform-comment:No experimental confirmation available. Contains a omega-N-methylarginine at position 249.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:8kgpssCRrHiTHsFaOH2nDK6EIjk559292	rogid:NFXIvVJoroP1SezcZfQYKHTlTR09606	intact-crc:D2D94627A7D835AA|rigid:D7Jga27uEEhBeK+L+m1yop8Wfsk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40956	uniprotkb:O43186	intact:EBI-7968|uniprotkb:D6VTX2|ensemblfungi:YGL181W	intact:EBI-748171|uniprotkb:Q0QD45|ensembl:ENSP00000221996|ensembl:ENSP00000445565	psi-mi:gts1_yeast(display_long)|uniprotkb:YGL181W(locus name)|uniprotkb:GTS1(gene name)|psi-mi:GTS1(display_short)|uniprotkb:LSR1(gene name synonym)|uniprotkb:Protein LSR1(gene name synonym)	psi-mi:crx_human(display_long)|uniprotkb:CRX(gene name)|psi-mi:CRX(display_short)|uniprotkb:CORD2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11542101|imex:IM-24995-2082	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011334.1|sgd:S000003149|mint:P40956|dip:DIP-2746N|ensemblfungi:YGL181W(gene)|ensemblfungi:YGL181W_mRNA(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0006897"(endocytosis)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010512"(negative regulation of phosphatidylinositol biosynthetic process)|go:"GO:0030479"(actin cortical patch)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR037278|interpro:IPR038508|sgd:YGL181W(identity)	refseq:NP_000545.1|ensembl:ENSG00000105392(gene)|ensembl:ENST00000221996(transcript)|ensembl:ENST00000539067(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007601"(visual perception)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050896"(response to stimulus)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013851(Transcription factor Otx, C-terminal)|interpro:IPR017970|entrezgene/locuslink:1406(identity)	-	crc64:D687E3BF6B620795	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:8kgpssCRrHiTHsFaOH2nDK6EIjk559292	rogid:v/bkO/0iLzq1Q2HtieWQQ40RF9M9606	intact-crc:6858AC531291A260|rigid:G2P8FEYVyuPKDDMlW1xHCR97OT8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O14641	uniprotkb:P40956	intact:EBI-740850|ensembl:ENSP00000005340|uniprotkb:Q53XM0|uniprotkb:D3DTN3	intact:EBI-7968|uniprotkb:D6VTX2|ensemblfungi:YGL181W	psi-mi:dvl2_human(display_long)|uniprotkb:DSH homolog 2(gene name synonym)|uniprotkb:DVL2(gene name)|psi-mi:DVL2(display_short)	psi-mi:gts1_yeast(display_long)|uniprotkb:YGL181W(locus name)|uniprotkb:GTS1(gene name)|psi-mi:GTS1(display_short)|uniprotkb:LSR1(gene name synonym)|uniprotkb:Protein LSR1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11542092|imex:IM-24995-2081	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004413.1|ensembl:ENSG00000004975(gene)|ensembl:ENST00000005340(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005109"(frizzled binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0007507"(heart development)|go:"GO:0016235"(aggresome)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044340"(canonical Wnt signaling pathway involved in regulation of cell proliferation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0150012"(positive regulation of neuron projection arborization)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008341(Dishevelled-2 region)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:O14641|rcsb pdb:2REY|rcsb pdb:3CBX|rcsb pdb:3CBY|rcsb pdb:3CBZ|rcsb pdb:3CC0|rcsb pdb:4WIP|rcsb pdb:5LNP|rcsb pdb:5SUY|rcsb pdb:5SUZ|rcsb pdb:6IW3|rcsb pdb:6JCK|reactome:R-HSA-201681|reactome:R-HSA-201688|reactome:R-HSA-2028269|reactome:R-HSA-4086400|reactome:R-HSA-4608870|reactome:R-HSA-4641258|reactome:R-HSA-4641262|reactome:R-HSA-5099900|reactome:R-HSA-5368598|reactome:R-HSA-5663220|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9673324|ensembl:ENSP00000005340|dip:DIP-34433N|entrezgene/locuslink:1856(identity)	refseq:NP_011334.1|sgd:S000003149|mint:P40956|dip:DIP-2746N|ensemblfungi:YGL181W(gene)|ensemblfungi:YGL181W_mRNA(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0006897"(endocytosis)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010512"(negative regulation of phosphatidylinositol biosynthetic process)|go:"GO:0030479"(actin cortical patch)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR037278|interpro:IPR038508|sgd:YGL181W(identity)	-	-	crc64:D687E3BF6B620795	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:2Vdc8oRnT4Mz/j+EXQXrL3AszOc9606	rogid:8kgpssCRrHiTHsFaOH2nDK6EIjk559292	intact-crc:F45C986D1DDD2553|rigid:f+XqEw2aghQg19Q6AH+2v3F0+68	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40956	uniprotkb:A0A0A0MQZ8	intact:EBI-7968|uniprotkb:D6VTX2|ensemblfungi:YGL181W	intact:EBI-11531560|ensembl:ENSP00000297183	psi-mi:gts1_yeast(display_long)|uniprotkb:YGL181W(locus name)|uniprotkb:GTS1(gene name)|psi-mi:GTS1(display_short)|uniprotkb:LSR1(gene name synonym)|uniprotkb:Protein LSR1(gene name synonym)	psi-mi:a0a0a0mqz8_human(display_long)|uniprotkb:ANKHD1(gene name)|psi-mi:ANKHD1(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11542083|imex:IM-24995-2080	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011334.1|sgd:S000003149|mint:P40956|dip:DIP-2746N|ensemblfungi:YGL181W(gene)|ensemblfungi:YGL181W_mRNA(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0006897"(endocytosis)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010512"(negative regulation of phosphatidylinositol biosynthetic process)|go:"GO:0030479"(actin cortical patch)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR037278|interpro:IPR038508|sgd:YGL181W(identity)	ensembl:ENSG00000131503(gene)|ensembl:ENST00000297183(transcript)|go:"GO:0003723"(RNA binding)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR036612|entrezgene/locuslink:54882(identity)	-	crc64:D687E3BF6B620795	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:8kgpssCRrHiTHsFaOH2nDK6EIjk559292	rogid:o5PbZ86LdldDZqy6ao7ukLpABbE9606	intact-crc:0B2B33792914A849|rigid:/22GAeVY0E/rn992a9sDkg20l8w	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96BA8	uniprotkb:P40857	intact:EBI-6942903|ensembl:ENSP00000481956|intact:MINT-268046|intact:MINT-8162577|uniprotkb:Q8N2D5|uniprotkb:Q96CP0	intact:EBI-26003|uniprotkb:D6VW87|ensemblfungi:YJL097W	psi-mi:cr3l1_human(display_long)|uniprotkb:CREB3L1(gene name)|psi-mi:CREB3L1(display_short)|uniprotkb:OASIS(gene name synonym)|uniprotkb:PSEC0238(orf name)|uniprotkb:Old astrocyte specifically-induced substance(gene name synonym)	psi-mi:hacd_yeast(display_long)|uniprotkb:YJL097W(locus name)|uniprotkb:J0902(orf name)|uniprotkb:PTPLA homolog involved in sphingolipid biosynthesis protein 1(gene name synonym)|uniprotkb:PHS1(gene name)|psi-mi:PHS1(display_short)|uniprotkb:3-hydroxyacyl-CoA dehydratase PHS1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11542074|imex:IM-24995-2079	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157613(gene)|ensembl:ENST00000621158(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0070278"(extracellular matrix constituent secretion)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029805|mint:Q96BA8|reactome:R-HSA-8874211|refseq:NP_443086.1|entrezgene/locuslink:90993(identity)	refseq:NP_012438.1|sgd:S000003633|reactome:R-SCE-75876|dip:DIP-2104N|ensemblfungi:YJL097W(gene)|ensemblfungi:YJL097W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0004300"(enoyl-CoA hydratase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0042175"(nuclear outer membrane-endoplasmic reticulum membrane network)|go:"GO:0042761"(very long-chain fatty acid biosynthetic process)|go:"GO:0102158"(very-long-chain 3-hydroxyacyl-CoA dehydratase activity)|go:"GO:0102343"(3-hydroxy-arachidoyl-CoA dehydratase activity)|go:"GO:0102344"(3-hydroxy-behenoyl-CoA dehydratase activity)|go:"GO:0102345"(3-hydroxy-lignoceroyl-CoA dehydratase activity)|interpro:IPR007482(Protein-tyrosine phosphatase-like, PTPLA)|go:"GO:0007034"(vacuolar transport)|go:"GO:0018812"(3-hydroxyacyl-CoA dehydratase activity)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030497"(fatty acid elongation)|sgd:YJL097W(identity)	-	comment:mint|function:"Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE"	crc64:5C87BC9563FB83AA	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:sMWUFmBeBBCO+T0Y2CuB/un1lBg9606	rogid:4C/5U50EeqZ6OR+MR8zFHLo36s8559292	intact-crc:87D01884F34D490B|rigid:hgunBsGSYaLR369OyA9xNP3usLI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96B96	uniprotkb:P40581	intact:EBI-7055862|ensembl:ENSP00000233047|ensembl:ENSP00000261388|ensembl:ENSP00000460687|ensembl:ENSP00000492164|ensembl:ENSP00000492501|ensembl:ENSP00000491056|intact:MINT-8163962|intact:MINT-8201794|uniprotkb:A6NMA9|uniprotkb:O00323|uniprotkb:B4DEC1	intact:EBI-7869|ensemblfungi:YIR037W|uniprotkb:D6VVW8	psi-mi:ldaf1_human(display_long)|uniprotkb:LDAF1(gene name)|psi-mi:LDAF1(display_short)|uniprotkb:Promethin(gene name synonym)|uniprotkb:TMEM159(gene name synonym)|uniprotkb:Transmembrane protein 159(gene name synonym)	psi-mi:gpx3_yeast(display_long)|uniprotkb:HYR1(gene name)|psi-mi:HYR1(display_short)|uniprotkb:ORP1(gene name synonym)|uniprotkb:Hydrogen peroxide resistance protein 1(gene name synonym)|uniprotkb:Oxidant receptor peroxidase 1(gene name synonym)|uniprotkb:Phospholipid hydroperoxide glutathione peroxidase 3(gene name synonym)|uniprotkb:GPX3(gene name synonym)|uniprotkb:YIR037W(locus name)|uniprotkb:Glutathione peroxidase homolog 3(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11542065|imex:IM-24995-2078	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001288698.1|refseq:NP_001288700.1|refseq:NP_001288702.1|refseq:NP_001288703.1|refseq:NP_001288704.1|ensembl:ENSG00000011638(gene)|ensembl:ENSG00000283997(gene)|ensembl:ENST00000233047(transcript)|ensembl:ENST00000261388(transcript)|ensembl:ENST00000572599(transcript)|ensembl:ENST00000638934(transcript)|ensembl:ENST00000640188(transcript)|ensembl:ENST00000640514(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0016021"(integral component of membrane)|go:"GO:0140042"(lipid droplet formation)|interpro:IPR029709|mint:Q96B96|refseq:NP_065155.3|refseq:XP_005255496.1|refseq:XP_006721129.1|entrezgene/locuslink:57146(identity)	refseq:NP_012303.1|sgd:S000001476|ensemblfungi:YIR037W(gene)|ensemblfungi:YIR037W_mRNA(transcript)|go:"GO:0004601"(peroxidase activity)|go:"GO:0004602"(glutathione peroxidase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005829"(cytosol)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0047066"(phospholipid-hydroperoxide glutathione peroxidase activity)|go:"GO:0051920"(peroxiredoxin activity)|interpro:IPR000889(Glutathione peroxidase)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR029760|interpro:IPR036249|rcsb pdb:3CMI|reactome:R-SCE-2142712|reactome:R-SCE-9018676|reactome:R-SCE-9018896|reactome:R-SCE-9020265|reactome:R-SCE-9023661|interpro:IPR029759|mint:P40581|dip:DIP-1275N|sgd:YIR037W(identity)	-	comment:mint	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:qDMjn8OVxY8eRUFJTc8hxD3Tk0c9606	rogid:Pi8aaZEVc33CTMPyaM0mpscvLU4559292	intact-crc:02B7516126BCBB23|rigid:mgnY5oY9Y6iSPiFRmMFG4UvDHng	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40567	uniprotkb:Q8N6L0	intact:EBI-789|uniprotkb:D6VVT9|ensemblfungi:YIR009W	intact:EBI-749265|uniprotkb:Q96MC3|ensembl:ENSP00000404220	psi-mi:msl1_yeast(display_long)|uniprotkb:YIB9W(orf name)|uniprotkb:YIR009W(locus name)|uniprotkb:MSL1(gene name)|psi-mi:MSL1(display_short)	psi-mi:kash5_human(display_long)|uniprotkb:KASH5(gene name)|psi-mi:KASH5(display_short)|uniprotkb:CCDC155(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 155(gene name synonym)|uniprotkb:KASH domain-containing protein 5(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11542056|imex:IM-24995-2077	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012274.1|sgd:S000001448|rcsb pdb:6BK8|ensemblfungi:YIR009W(gene)|ensemblfungi:YIR009W_mRNA(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005685"(U1 snRNP)|go:"GO:0030619"(U1 snRNA binding)|go:"GO:0030620"(U2 snRNA binding)|go:"GO:0071004"(U2-type prespliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5MQ0|rcsb pdb:5NRL|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:5ZWM|rcsb pdb:5ZWO|dip:DIP-816N|mint:P40567|rcsb pdb:6EXN|rcsb pdb:6G90|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|sgd:YIR009W(identity)	refseq:NP_653289.3|ensembl:ENSG00000161609(gene)|ensembl:ENST00000447857(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034397"(telomere localization)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051225"(spindle assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0090172"(microtubule cytoskeleton organization involved in homologous chromosome segregation)|go:"GO:0090220"(chromosome localization to nuclear envelope involved in homologous chromosome segregation)|go:"GO:0090619"(meiotic spindle pole)|interpro:IPR011992(EF-Hand type)|interpro:IPR028168|interpro:IPR028170|interpro:IPR039508|mint:Q8N6L0|rcsb pdb:6R2I|rcsb pdb:6WMF|entrezgene/locuslink:147872(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:GAiHZKcbfNjbem3+i1cZXFm4NfE559292	rogid:Wl9L7AcvDHCZuKjYLn8QgGIbZTc9606	intact-crc:4035E67750B4E17F|rigid:n1Ez7t+dqoZQpQT8zY35xI/j6uY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P56279	uniprotkb:P40560	intact:EBI-749995|uniprotkb:Q6IBK7|ensembl:ENSP00000385036|ensembl:ENSP00000450496|ensembl:ENSP00000450701|ensembl:ENSP00000451506	intact:EBI-24911|uniprotkb:D6VVT0|ensemblfungi:YIL001W	psi-mi:tcl1a_human(display_long)|uniprotkb:Protein p14 TCL1(gene name synonym)|uniprotkb:Oncogene TCL-1(gene name synonym)|uniprotkb:TCL1A(gene name)|psi-mi:TCL1A(display_short)|uniprotkb:TCL1(gene name synonym)	psi-mi:yia1_yeast(display_long)|uniprotkb:YIA1W(orf name)|uniprotkb:YIL001W(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11542047|imex:IM-24995-2076	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001092195.1|refseq:NP_068801.1|refseq:XP_016877165.1|refseq:XP_016877166.1|dip:DIP-60787N|ensembl:ENSG00000100721(gene)|ensembl:ENST00000402399(transcript)|ensembl:ENST00000554012(transcript)|ensembl:ENST00000555202(transcript)|ensembl:ENST00000556450(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010918"(positive regulation of mitochondrial membrane potential)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|interpro:IPR004832(TCL1/MTCP1)|interpro:IPR036672|rcsb pdb:1JSG|entrezgene/locuslink:8115(identity)	sgd:S000001263|refseq:NP_012265.3|dip:DIP-1375N|ensemblfungi:YIL001W(gene)|ensemblfungi:YIL001W_mRNA(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0005737"(cytoplasm)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR036770|interpro:IPR044515|sgd:YIL001W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:c3GIYkYNb+wWlxn59oU2vpvbfhI9606	rogid:IOv6oxjYJ3W/jLnmIcM03RDQ8Ww559292	intact-crc:437C393AB478A031|rigid:QdJLKH/PLO6O2Zc3fR0ilnWuV+8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40560	uniprotkb:P26641	intact:EBI-24911|uniprotkb:D6VVT0|ensemblfungi:YIL001W	intact:EBI-351467|uniprotkb:Q6PJ62|uniprotkb:Q6PK31|uniprotkb:Q96CU2|uniprotkb:Q9P196|intact:EBI-2321928|uniprotkb:B4DTG2|ensembl:ENSP00000331901	psi-mi:yia1_yeast(display_long)|uniprotkb:YIA1W(orf name)|uniprotkb:YIL001W(locus name)	psi-mi:ef1g_human(display_long)|uniprotkb:PRO1608(orf name)|uniprotkb:EEF1G(gene name)|psi-mi:EEF1G(display_short)|uniprotkb:EF1G(gene name synonym)|uniprotkb:eEF-1B gamma(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11542038|imex:IM-24995-2075	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000001263|refseq:NP_012265.3|dip:DIP-1375N|ensemblfungi:YIL001W(gene)|ensemblfungi:YIL001W_mRNA(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0005737"(cytoplasm)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR036770|interpro:IPR044515|sgd:YIL001W(identity)	refseq:NP_001395.1|ensembl:ENSG00000254772(gene)|ensembl:ENST00000329251(transcript)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006414"(translational elongation)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001662(Translation elongation factor EF1B, gamma chain, conserved)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR036249|interpro:IPR036282|interpro:IPR036433|interpro:IPR040079|mint:P26641|rcsb pdb:1PBU|rcsb pdb:5DQS|rcsb pdb:5JPO|reactome:R-HSA-156842|dip:DIP-32516N|entrezgene/locuslink:1937(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:IOv6oxjYJ3W/jLnmIcM03RDQ8Ww559292	rogid:biVN96umeEdPm/wvPN4VwbSRHTs9606	intact-crc:903951206A82E4B0|rigid:5DcFCkb5tofX9knZyCskKKL7DSI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8N5R6	uniprotkb:P40560	intact:EBI-740841|intact:EBI-953781|uniprotkb:B3KQ49|uniprotkb:A8K3U4|uniprotkb:A8MPQ6|uniprotkb:A8MV61|uniprotkb:A8MVU9|uniprotkb:Q9H5Q6|uniprotkb:Q8TAX6|intact:EBI-2320546|intact:EBI-11522976	intact:EBI-24911|uniprotkb:D6VVT0|ensemblfungi:YIL001W	psi-mi:ccd33_human(display_long)|uniprotkb:CCDC33(gene name)|psi-mi:CCDC33(display_short)|uniprotkb:Cancer/testis antigen 61(gene name synonym)	psi-mi:yia1_yeast(display_long)|uniprotkb:YIA1W(orf name)|uniprotkb:YIL001W(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11542029|imex:IM-24995-2074	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_079331.3|interpro:IPR000008(C2 calcium-dependent membrane targeting)|go:"GO:0005777"(peroxisome)|refseq:NP_001274110.1|refseq:NP_877592.2|mint:Q8N5R6|interpro:IPR035892|interpro:IPR039889|entrezgene/locuslink:80125(identity)	sgd:S000001263|refseq:NP_012265.3|dip:DIP-1375N|ensemblfungi:YIL001W(gene)|ensemblfungi:YIL001W_mRNA(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0005737"(cytoplasm)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR036770|interpro:IPR044515|sgd:YIL001W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2021/11/30	rogid:eEIn7pQyfdHWx8TeLJpYy0i/gww9606	rogid:IOv6oxjYJ3W/jLnmIcM03RDQ8Ww559292	intact-crc:F274426AEBC114E5|rigid:pxGUZW0PhxoZskEkamFgZBgxPHE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40956	uniprotkb:Q9BQY4	intact:EBI-7968|uniprotkb:D6VTX2|ensemblfungi:YGL181W	intact:EBI-372094|uniprotkb:Q9BR00|ensembl:ENSP00000360441	psi-mi:gts1_yeast(display_long)|uniprotkb:YGL181W(locus name)|uniprotkb:GTS1(gene name)|psi-mi:GTS1(display_short)|uniprotkb:LSR1(gene name synonym)|uniprotkb:Protein LSR1(gene name synonym)	psi-mi:rhxf2_human(display_long)|uniprotkb:RHOXF2(gene name)|psi-mi:RHOXF2(display_short)|uniprotkb:THG1(gene name synonym)|uniprotkb:Paired-like homeobox protein PEPP-2(gene name synonym)|uniprotkb:Testis homeobox gene 1(gene name synonym)|uniprotkb:PEPP2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11542197|imex:IM-24995-2092	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011334.1|sgd:S000003149|mint:P40956|dip:DIP-2746N|ensemblfungi:YGL181W(gene)|ensemblfungi:YGL181W_mRNA(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0006897"(endocytosis)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010512"(negative regulation of phosphatidylinositol biosynthetic process)|go:"GO:0030479"(actin cortical patch)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR037278|interpro:IPR038508|sgd:YGL181W(identity)	refseq:NP_115887.1|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0042802"(identical protein binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|ensembl:ENSG00000131721(gene)|ensembl:ENST00000371388(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|entrezgene/locuslink:84528(identity)	-	crc64:D687E3BF6B620795	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:8kgpssCRrHiTHsFaOH2nDK6EIjk559292	rogid:shpgPqf80gNt+gFDv1K+827ELUQ9606	intact-crc:0EF66C0DFDFFBA95|rigid:RFaTOGL6SABsauK/jjDGC+NhWAY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96MA1	uniprotkb:P40956	intact:EBI-954466|uniprotkb:Q96SD2|ensembl:ENSP00000360500	intact:EBI-7968|uniprotkb:D6VTX2|ensemblfungi:YGL181W	psi-mi:dmrtb_human(display_long)|uniprotkb:DMRTB1(gene name)|psi-mi:DMRTB1(display_short)	psi-mi:gts1_yeast(display_long)|uniprotkb:YGL181W(locus name)|uniprotkb:GTS1(gene name)|psi-mi:GTS1(display_short)|uniprotkb:LSR1(gene name synonym)|uniprotkb:Protein LSR1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11542186|imex:IM-24995-2091	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|ensembl:ENSG00000143006(gene)|ensembl:ENST00000371445(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007281"(germ cell development)|go:"GO:0007548"(sex differentiation)|go:"GO:0046872"(metal ion binding)|interpro:IPR001275(DM DNA-binding)|interpro:IPR026607|interpro:IPR036407|mint:Q96MA1|refseq:NP_149056.1|ensembl:ENSP00000360500|entrezgene/locuslink:63948(identity)	refseq:NP_011334.1|sgd:S000003149|mint:P40956|dip:DIP-2746N|ensemblfungi:YGL181W(gene)|ensemblfungi:YGL181W_mRNA(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0006897"(endocytosis)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010512"(negative regulation of phosphatidylinositol biosynthetic process)|go:"GO:0030479"(actin cortical patch)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR037278|interpro:IPR038508|sgd:YGL181W(identity)	-	-	crc64:D687E3BF6B620795	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:GU1xgsv/Oyy91PEorOlxBqAvIzc9606	rogid:8kgpssCRrHiTHsFaOH2nDK6EIjk559292	intact-crc:5122956AF16202AA|rigid:uwFrWjBNeLBqWbAyoWmobXU9zyQ	false	sufficient binding region:154-342	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40956	uniprotkb:Q93062-3	intact:EBI-7968|uniprotkb:D6VTX2|ensemblfungi:YGL181W	intact:EBI-740343|ensembl:ENSP00000340176	psi-mi:gts1_yeast(display_long)|uniprotkb:YGL181W(locus name)|uniprotkb:GTS1(gene name)|psi-mi:GTS1(display_short)|uniprotkb:LSR1(gene name synonym)|uniprotkb:Protein LSR1(gene name synonym)	psi-mi:q93062-3(display_long)|uniprotkb:RBPMS(gene name)|psi-mi:RBPMS(display_short)|uniprotkb:HERMES(gene name synonym)|uniprotkb:Heart and RRM expressed sequence(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11542177|imex:IM-24995-2090	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011334.1|sgd:S000003149|mint:P40956|dip:DIP-2746N|ensemblfungi:YGL181W(gene)|ensemblfungi:YGL181W_mRNA(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0006897"(endocytosis)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010512"(negative regulation of phosphatidylinositol biosynthetic process)|go:"GO:0030479"(actin cortical patch)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR037278|interpro:IPR038508|sgd:YGL181W(identity)	intact:EBI-740322(rbpms_human)|uniprotkb:Q93062-3(isoform-parent)|ensembl:ENSG00000157110(gene)|ensembl:ENST00000339877(transcript)|entrezgene/locuslink:11030(identity)	-	crc64:D687E3BF6B620795	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:8kgpssCRrHiTHsFaOH2nDK6EIjk559292	rogid:nlPMQAJoKEbPYBwsL3xodmCKd7c9606	intact-crc:33BB406FF579867A|rigid:l+njoww6eYylGUddB6RVXgcNerY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40956	uniprotkb:Q92734	intact:EBI-7968|uniprotkb:D6VTX2|ensemblfungi:YGL181W	intact:EBI-357061|uniprotkb:Q15656|intact:EBI-357314|uniprotkb:Q969I2|uniprotkb:D3DN49|uniprotkb:K0J5S8|uniprotkb:K0J6K2|intact:EBI-28969365|ensembl:ENSP00000240851|ensembl:ENSP00000419960|ensembl:ENSP00000420797|ensembl:ENSP00000501815|ensembl:ENSP00000502071|ensembl:ENSP00000502450|ensembl:ENSP00000502592|ensembl:ENSP00000502734|uniprotkb:G5E9V1	psi-mi:gts1_yeast(display_long)|uniprotkb:YGL181W(locus name)|uniprotkb:GTS1(gene name)|psi-mi:GTS1(display_short)|uniprotkb:LSR1(gene name synonym)|uniprotkb:Protein LSR1(gene name synonym)	psi-mi:tfg_human(display_long)|uniprotkb:TFG(gene name)|psi-mi:TFG(display_short)|uniprotkb:TRK-fused gene protein(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11542168|imex:IM-24995-2089	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011334.1|sgd:S000003149|mint:P40956|dip:DIP-2746N|ensemblfungi:YGL181W(gene)|ensemblfungi:YGL181W_mRNA(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0006897"(endocytosis)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010512"(negative regulation of phosphatidylinositol biosynthetic process)|go:"GO:0030479"(actin cortical patch)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR037278|interpro:IPR038508|sgd:YGL181W(identity)	refseq:NP_001007566.1|refseq:NP_001182407.1|refseq:NP_001182408.1|refseq:NP_006061.2|ensembl:ENSP00000240851|ensembl:ENST00000463568|ensembl:ENSP00000419504|ensembl:ENST00000476228|ensembl:ENSP00000417952|ensembl:ENSP00000420797|ensembl:ENSP00000419960|ensembl:ENST00000615993|ensembl:ENSP00000479269|ensembl:ENST00000620299|ensembl:ENSP00000479981|ensembl:ENSP00000502734|ensembl:ENST00000674645|ensembl:ENSP00000501892|ensembl:ENST00000674758|ensembl:ENSP00000502502|ensembl:ENST00000675047|ensembl:ENSP00000502497|ensembl:ENSP00000502592|ensembl:ENST00000675420|ensembl:ENSP00000502516|ensembl:ENSP00000502450|ensembl:ENST00000675543|ensembl:ENSP00000501815|ensembl:ENST00000675586|ensembl:ENSP00000502329|ensembl:ENST00000676111|ensembl:ENSP00000502139|ensembl:ENST00000676308|ensembl:ENSP00000502697|ensembl:ENSP00000502071|ensembl:ENST00000676431|ensembl:ENSP00000502698|ensembl:ENSP00000502229|refseq:XP_006713535.1|refseq:XP_006713536.1|ensembl:ENSG00000114354(gene)|ensembl:ENST00000240851(transcript)|ensembl:ENST00000487505(transcript)|ensembl:ENST00000490574(transcript)|ensembl:ENST00000674615(transcript)|ensembl:ENST00000675243(transcript)|ensembl:ENST00000675499(transcript)|ensembl:ENST00000675553(transcript)|ensembl:ENST00000676395(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048208"(COPII vesicle coating)|go:"GO:0070971"(endoplasmic reticulum exit site)|interpro:IPR000270(Octicosapeptide/Phox/Bem1p)|interpro:IPR033512|interpro:IPR034857|mint:Q92734|reactome:R-HSA-204005|refseq:XP_011510636.1|refseq:XP_005247123.1|refseq:XP_016861016.1|refseq:XP_016861017.1|refseq:XP_016861018.1|refseq:XP_016861019.1|entrezgene/locuslink:10342(identity)	-	crc64:D687E3BF6B620795	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:8kgpssCRrHiTHsFaOH2nDK6EIjk559292	rogid:y7aghh0X3Ewgpzcx5h5nB+X2dII9606	intact-crc:4E2189FF246E389B|rigid:/k+kbKNm/+JBeWuHk0bYBxyr74M	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40956	uniprotkb:Q8N684-3	intact:EBI-7968|uniprotkb:D6VTX2|ensemblfungi:YGL181W	intact:EBI-11523759|ensembl:ENSP00000345412	psi-mi:gts1_yeast(display_long)|uniprotkb:YGL181W(locus name)|uniprotkb:GTS1(gene name)|psi-mi:GTS1(display_short)|uniprotkb:LSR1(gene name synonym)|uniprotkb:Protein LSR1(gene name synonym)	psi-mi:q8n684-3(display_long)|uniprotkb:Cleavage factor Im complex 59 kDa subunit(gene name synonym)|uniprotkb:CPSF7(gene name)|psi-mi:CPSF7(display_short)|uniprotkb:Cleavage and polyadenylation specificity factor 59 kDa subunit(gene name synonym)|uniprotkb:Pre-mRNA cleavage factor Im 59 kDa subunit(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11542157|imex:IM-24995-2088	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011334.1|sgd:S000003149|mint:P40956|dip:DIP-2746N|ensemblfungi:YGL181W(gene)|ensemblfungi:YGL181W_mRNA(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0006897"(endocytosis)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010512"(negative regulation of phosphatidylinositol biosynthetic process)|go:"GO:0030479"(actin cortical patch)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR037278|interpro:IPR038508|sgd:YGL181W(identity)	intact:EBI-746909(isoform-parent)|ensembl:ENSG00000149532(gene)|ensembl:ENST00000340437(transcript)|uniprotkb:Q8N684-3(isoform-parent)|entrezgene/locuslink:79869(identity)	-	crc64:D687E3BF6B620795	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:8kgpssCRrHiTHsFaOH2nDK6EIjk559292	rogid:hnk6o9HBKsdIRWKRuEdjdByVKxM9606	intact-crc:EBFED4C772B4F7AB|rigid:vh7qvcU5v39+DjimLgDnPocm+bE	false	-	sufficient binding region:44-514	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q6P1W5	uniprotkb:P40956	intact:EBI-946029|uniprotkb:B3KVT1|uniprotkb:Q96IC8|ensembl:ENSP00000435634|uniprotkb:D3DPR3|uniprotkb:E9PJ76	intact:EBI-7968|uniprotkb:D6VTX2|ensemblfungi:YGL181W	psi-mi:ca094_human(display_long)|uniprotkb:C1orf94(gene name)|psi-mi:C1orf94(display_short)	psi-mi:gts1_yeast(display_long)|uniprotkb:YGL181W(locus name)|uniprotkb:GTS1(gene name)|psi-mi:GTS1(display_short)|uniprotkb:LSR1(gene name synonym)|uniprotkb:Protein LSR1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11542146|imex:IM-24995-2087	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001128206.1|refseq:NP_116273.2|ensembl:ENSG00000142698(gene)|ensembl:ENST00000488417(transcript)|interpro:IPR031496|entrezgene/locuslink:84970(identity)	refseq:NP_011334.1|sgd:S000003149|mint:P40956|dip:DIP-2746N|ensemblfungi:YGL181W(gene)|ensemblfungi:YGL181W_mRNA(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0006897"(endocytosis)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010512"(negative regulation of phosphatidylinositol biosynthetic process)|go:"GO:0030479"(actin cortical patch)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR037278|interpro:IPR038508|sgd:YGL181W(identity)	-	-	crc64:D687E3BF6B620795	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:y1o4xWvTl2CBA1J7jsP7y8ZjLzM9606	rogid:8kgpssCRrHiTHsFaOH2nDK6EIjk559292	intact-crc:11215DDD4BFD3933|rigid:2rsxj/TugFNarklH///ujv8mEKg	false	sufficient binding region:191-598	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40956	uniprotkb:Q15038	intact:EBI-7968|uniprotkb:D6VTX2|ensemblfungi:YGL181W	intact:EBI-724310|ensembl:ENSP00000394699|uniprotkb:E9PB45|uniprotkb:A8K254|uniprotkb:B4DDT5|uniprotkb:C9JA96|uniprotkb:C9JP84|uniprotkb:B4E1G3|uniprotkb:F8VU62	psi-mi:gts1_yeast(display_long)|uniprotkb:YGL181W(locus name)|uniprotkb:GTS1(gene name)|psi-mi:GTS1(display_short)|uniprotkb:LSR1(gene name synonym)|uniprotkb:Protein LSR1(gene name synonym)	psi-mi:dazp2_human(display_long)|uniprotkb:Deleted in azoospermia-associated protein 2(gene name synonym)|uniprotkb:DAZAP2(gene name)|psi-mi:DAZAP2(display_short)|uniprotkb:KIAA0058(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11542137|imex:IM-24995-2086	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011334.1|sgd:S000003149|mint:P40956|dip:DIP-2746N|ensemblfungi:YGL181W(gene)|ensemblfungi:YGL181W_mRNA(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0006897"(endocytosis)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010512"(negative regulation of phosphatidylinositol biosynthetic process)|go:"GO:0030479"(actin cortical patch)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR037278|interpro:IPR038508|sgd:YGL181W(identity)	ensembl:ENSG00000183283(gene)|ensembl:ENST00000412716(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0016607"(nuclear speck)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0050699"(WW domain binding)|interpro:IPR022730|mint:Q15038|refseq:NP_001129736.1|refseq:NP_055579.1|ensembl:ENSP00000394699|ensembl:ENST00000425012|ensembl:ENSP00000408251|ensembl:ENST00000439799|ensembl:ENSP00000398804|ensembl:ENST00000449723|ensembl:ENSP00000412812|ensembl:ENST00000549555|ensembl:ENSP00000448051|ensembl:ENST00000549732|ensembl:ENSP00000446554|refseq:NP_001129741.1|refseq:NP_001129739.1|refseq:NP_001129740.1|refseq:NP_001129738.1|entrezgene/locuslink:9802(identity)	-	crc64:D687E3BF6B620795	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:8kgpssCRrHiTHsFaOH2nDK6EIjk559292	rogid:ASRqCZBG4q1U/y95PUSMKsgfm/g9606	intact-crc:0992008B183E16DE|rigid:tq/jX7xeiamy1eGRo5l6cuOWtgU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40956	uniprotkb:P63279	intact:EBI-7968|uniprotkb:D6VTX2|ensemblfungi:YGL181W	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	psi-mi:gts1_yeast(display_long)|uniprotkb:YGL181W(locus name)|uniprotkb:GTS1(gene name)|psi-mi:GTS1(display_short)|uniprotkb:LSR1(gene name synonym)|uniprotkb:Protein LSR1(gene name synonym)	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11542128|imex:IM-24995-2085	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011334.1|sgd:S000003149|mint:P40956|dip:DIP-2746N|ensemblfungi:YGL181W(gene)|ensemblfungi:YGL181W_mRNA(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0006897"(endocytosis)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010512"(negative regulation of phosphatidylinositol biosynthetic process)|go:"GO:0030479"(actin cortical patch)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR037278|interpro:IPR038508|sgd:YGL181W(identity)	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N|entrezgene/locuslink:7329(identity)	-	crc64:D687E3BF6B620795	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:8kgpssCRrHiTHsFaOH2nDK6EIjk559292	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	intact-crc:C5E37270ED4F5DB1|rigid:wtK95pRnYCE8bf/gF5tg06A8uk8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40956	uniprotkb:P23511-2	intact:EBI-7968|uniprotkb:D6VTX2|ensemblfungi:YGL181W	intact:EBI-11061759|ensembl:ENSP00000229418	psi-mi:gts1_yeast(display_long)|uniprotkb:YGL181W(locus name)|uniprotkb:GTS1(gene name)|psi-mi:GTS1(display_short)|uniprotkb:LSR1(gene name synonym)|uniprotkb:Protein LSR1(gene name synonym)	psi-mi:p23511-2(display_long)|uniprotkb:NFYA(gene name)|psi-mi:NFYA(display_short)|uniprotkb:CAAT box DNA-binding protein subunit A(gene name synonym)|uniprotkb:Nuclear transcription factor Y subunit A(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11542119|imex:IM-24995-2084	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011334.1|sgd:S000003149|mint:P40956|dip:DIP-2746N|ensemblfungi:YGL181W(gene)|ensemblfungi:YGL181W_mRNA(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0006897"(endocytosis)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010512"(negative regulation of phosphatidylinositol biosynthetic process)|go:"GO:0030479"(actin cortical patch)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR037278|interpro:IPR038508|sgd:YGL181W(identity)	intact:EBI-389739(isoform-parent)|ensembl:ENSG00000001167(gene)|ensembl:ENST00000353205(transcript)|uniprotkb:P23511-2(isoform-parent)|entrezgene/locuslink:4800(identity)	-	crc64:D687E3BF6B620795	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:8kgpssCRrHiTHsFaOH2nDK6EIjk559292	rogid:9IOUoaGszX6kd9hzrCj6BBkgJ+09606	intact-crc:FE08EB3E4AF7E3F4|rigid:71UqtccFw4nTapWPLP3j01Da15k	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40692	uniprotkb:P42843	intact:EBI-744248|uniprotkb:B4DI13|uniprotkb:B4DQ11|uniprotkb:E9PCU2|ensembl:ENSP00000231790	intact:EBI-28370|uniprotkb:Q6B2L9|uniprotkb:D6W0N4|ensemblfungi:YNL311C	psi-mi:mlh1_human(display_long)|uniprotkb:MutL protein homolog 1(gene name synonym)|uniprotkb:MLH1(gene name)|psi-mi:MLH1(display_short)|uniprotkb:COCA2(gene name synonym)	psi-mi:skp2_yeast(display_long)|uniprotkb:N0376(orf name)|uniprotkb:YNL311C(locus name)|uniprotkb:SKP2(gene name)|psi-mi:SKP2(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11542288|imex:IM-24995-2102	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000240.1|refseq:NP_001161089.1|refseq:NP_001161090.1|refseq:NP_001161091.1|refseq:NP_001245200.1|refseq:NP_001245202.1|refseq:NP_001245203.1|dip:DIP-27601N|refseq:XP_005265220.1|refseq:XP_005265221.1|ensembl:ENSG00000076242(gene)|ensembl:ENST00000231790(transcript)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005712"(chiasma)|go:"GO:0005715"(late recombination nodule)|go:"GO:0006298"(mismatch repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0007060"(male meiosis chromosome segregation)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0009617"(response to bacterium)|go:"GO:0016020"(membrane)|go:"GO:0016321"(female meiosis chromosome segregation)|go:"GO:0016446"(somatic hypermutation of immunoglobulin genes)|go:"GO:0019899"(enzyme binding)|go:"GO:0032137"(guanine/thymine mispair binding)|go:"GO:0032300"(mismatch repair complex)|go:"GO:0032389"(MutLalpha complex)|go:"GO:0043060"(meiotic metaphase I plate congression)|go:"GO:0045141"(meiotic telomere clustering)|go:"GO:0045190"(isotype switching)|go:"GO:0045950"(negative regulation of mitotic recombination)|go:"GO:0048298"(positive regulation of isotype switching to IgA isotypes)|go:"GO:0048304"(positive regulation of isotype switching to IgG isotypes)|go:"GO:0048477"(oogenesis)|go:"GO:0051257"(meiotic spindle midzone assembly)|interpro:IPR002099(DNA mismatch repair protein)|interpro:IPR013507(DNA mismatch repair protein, C-terminal)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR014762(DNA mismatch repair, conserved site)|interpro:IPR020568|interpro:IPR032189|interpro:IPR036890|interpro:IPR038973|mint:P40692|rcsb pdb:3RBN|rcsb pdb:4P7A|rcsb pdb:5U5P|reactome:R-HSA-5358565|reactome:R-HSA-5358606|reactome:R-HSA-5545483|reactome:R-HSA-5632987|reactome:R-HSA-6796648|reactome:R-HSA-912446|entrezgene/locuslink:4292(identity)	refseq:NP_014088.1|sgd:S000005255|dip:DIP-1971N|ensemblfungi:YNL311C(gene)|ensemblfungi:YNL311C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031335"(regulation of sulfur amino acid metabolic process)|go:"GO:0044257"(cellular protein catabolic process)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR036047|sgd:YNL311C(identity)	-	-	crc64:81102168449051BC	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:v/ydpM1Cf5bF27dC+3JF6XXMp0Q9606	rogid:cvjKu9olqbvbZPvhBL6DK754CVA559292	intact-crc:78AFBFA30F60DEF6|rigid:kYwRq4BtBtFhSAL5N1qqzkJjwfs	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96BA8	uniprotkb:P42836	intact:EBI-6942903|ensembl:ENSP00000481956|intact:MINT-268046|intact:MINT-8162577|uniprotkb:Q8N2D5|uniprotkb:Q96CP0	intact:EBI-28414|uniprotkb:D6W0M1|ensemblfungi:YNL326C	psi-mi:cr3l1_human(display_long)|uniprotkb:CREB3L1(gene name)|psi-mi:CREB3L1(display_short)|uniprotkb:OASIS(gene name synonym)|uniprotkb:PSEC0238(orf name)|uniprotkb:Old astrocyte specifically-induced substance(gene name synonym)	psi-mi:pfa3_yeast(display_long)|uniprotkb:YNL326C(locus name)|uniprotkb:N0325(orf name)|uniprotkb:PFA3(gene name)|psi-mi:PFA3(display_short)|uniprotkb:Protein fatty acyltransferase 3(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11542278|imex:IM-24995-2101	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157613(gene)|ensembl:ENST00000621158(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0070278"(extracellular matrix constituent secretion)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029805|mint:Q96BA8|reactome:R-HSA-8874211|refseq:NP_443086.1|entrezgene/locuslink:90993(identity)	refseq:NP_014073.1|sgd:S000005270|dip:DIP-4833N|ensemblfungi:YNL326C(gene)|ensemblfungi:YNL326C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0042144"(vacuole fusion, non-autophagic)|interpro:IPR001594(Zinc finger, DHHC-type)|sgd:YNL326C(identity)	-	comment:mint|function:"Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE"	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:sMWUFmBeBBCO+T0Y2CuB/un1lBg9606	rogid:wDUIzJoLnfaV6fo96hca+beyKb4559292	intact-crc:6BA0FBFFE77B932B|rigid:+paqGEhcUkhG4sNChbNbQOAbHo0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P41911	uniprotkb:Q8NHQ1	intact:EBI-7791|uniprotkb:P50905|uniprotkb:D6W208|ensemblfungi:YOL059W	intact:EBI-739624|ensembl:ENSP00000264982|ensembl:ENSP00000419231|uniprotkb:Q96B31|uniprotkb:Q9H2C3|uniprotkb:Q9H2Z1|uniprotkb:Q9H940|uniprotkb:D3DNE9|uniprotkb:B7Z5I8|uniprotkb:B7Z7E8|uniprotkb:F5GZX8	psi-mi:gpd2_yeast(display_long)|uniprotkb:GPD2(gene name)|psi-mi:GPD2(display_short)|uniprotkb:GPD3(gene name synonym)|uniprotkb:YOL059W(locus name)|uniprotkb:O1222(orf name)	psi-mi:cep70_human(display_long)|uniprotkb:CEP70(gene name)|psi-mi:CEP70(display_short)|uniprotkb:BITE(gene name synonym)|uniprotkb:p10-binding protein(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11542269|imex:IM-24995-2100	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014582.1|sgd:S000005420|dip:DIP-1348N|mint:P41911|ensemblfungi:YOL059W(gene)|ensemblfungi:YOL059W_mRNA(transcript)|go:"GO:0004367"(glycerol-3-phosphate dehydrogenase [NAD+] activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006071"(glycerol metabolic process)|go:"GO:0006072"(glycerol-3-phosphate metabolic process)|go:"GO:0006116"(NADH oxidation)|go:"GO:0009331"(glycerol-3-phosphate dehydrogenase complex)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046168"(glycerol-3-phosphate catabolic process)|go:"GO:0051287"(NAD binding)|interpro:IPR006109(NAD-dependent glycerol-3-phosphate dehydrogenase, C-terminal)|interpro:IPR006168(NAD-dependent glycerol-3-phosphate dehydrogenase)|interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|interpro:IPR011128(NAD-dependent glycerol-3-phosphate dehydrogenase, N-terminal)|interpro:IPR013328(Dehydrogenase, multihelical)|interpro:IPR017751(NAD-dependent glycerol-3-phosphate dehydrogenase, eukaryotic)|interpro:IPR036291|reactome:R-SCE-1483166|sgd:YOL059W(identity)	ensembl:ENSG00000114107(gene)|ensembl:ENST00000264982(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|interpro:IPR019734|interpro:IPR037692|mint:Q8NHQ1|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|ensembl:ENST00000484888(transcript)|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_077817.2|refseq:XP_016862764.1|refseq:NP_001275893.1|refseq:NP_001275894.1|refseq:NP_001275895.1|refseq:NP_001275896.1|refseq:NP_001307527.1|refseq:NP_001307529.1|entrezgene/locuslink:80321(identity)	-	crc64:FA6C07034D3EC720	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:RX8TddHnpQdQdh6KN8y9IR8Jgrg559292	rogid:S4yveQWcvdVtAUX65gqrJ5Dv0Mc9606	intact-crc:B2022B06A877C715|rigid:Iu233k8WKSMtbV2xCJgemKCwEHI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q13137	uniprotkb:P41911	intact:EBI-739580|uniprotkb:B4DDC4|uniprotkb:E7ENK0|uniprotkb:Q53FQ5|uniprotkb:Q53HB5|uniprotkb:Q6IBN9|uniprotkb:Q9BTF7|uniprotkb:B2RBT0|ensembl:ENSP00000258947|uniprotkb:B4E0C0|uniprotkb:E7ETP5|uniprotkb:B4DDT4|uniprotkb:B4DP36|uniprotkb:E9PBE5	intact:EBI-7791|uniprotkb:P50905|uniprotkb:D6W208|ensemblfungi:YOL059W	psi-mi:caco2_human(display_long)|uniprotkb:CALCOCO2(gene name)|psi-mi:CALCOCO2(display_short)|uniprotkb:NDP52(gene name synonym)|uniprotkb:Nuclear domain 10 protein NDP52(gene name synonym)|uniprotkb:Antigen nuclear dot 52 kDa protein(gene name synonym)|uniprotkb:Nuclear dot protein 52(gene name synonym)	psi-mi:gpd2_yeast(display_long)|uniprotkb:GPD2(gene name)|psi-mi:GPD2(display_short)|uniprotkb:GPD3(gene name synonym)|uniprotkb:YOL059W(locus name)|uniprotkb:O1222(orf name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11542260|imex:IM-24995-2099	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001248319.1|refseq:NP_001248320.1|refseq:NP_001248322.1|refseq:NP_005822.1|ensembl:ENSG00000136436(gene)|ensembl:ENST00000258947(transcript)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016032"(viral process)|go:"GO:0016605"(PML body)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0098792"(xenophagy)|go:"GO:1901098"(positive regulation of autophagosome maturation)|interpro:IPR041611|interpro:IPR041641|mint:Q13137|rcsb pdb:2MXP|rcsb pdb:3VVV|rcsb pdb:3VVW|rcsb pdb:4GXL|rcsb pdb:4HAN|rcsb pdb:4XKL|rcsb pdb:5AAQ|rcsb pdb:5Z7A|rcsb pdb:5Z7L|refseq:NP_001248324.1|dip:DIP-57534N|entrezgene/locuslink:10241(identity)	refseq:NP_014582.1|sgd:S000005420|dip:DIP-1348N|mint:P41911|ensemblfungi:YOL059W(gene)|ensemblfungi:YOL059W_mRNA(transcript)|go:"GO:0004367"(glycerol-3-phosphate dehydrogenase [NAD+] activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006071"(glycerol metabolic process)|go:"GO:0006072"(glycerol-3-phosphate metabolic process)|go:"GO:0006116"(NADH oxidation)|go:"GO:0009331"(glycerol-3-phosphate dehydrogenase complex)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046168"(glycerol-3-phosphate catabolic process)|go:"GO:0051287"(NAD binding)|interpro:IPR006109(NAD-dependent glycerol-3-phosphate dehydrogenase, C-terminal)|interpro:IPR006168(NAD-dependent glycerol-3-phosphate dehydrogenase)|interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|interpro:IPR011128(NAD-dependent glycerol-3-phosphate dehydrogenase, N-terminal)|interpro:IPR013328(Dehydrogenase, multihelical)|interpro:IPR017751(NAD-dependent glycerol-3-phosphate dehydrogenase, eukaryotic)|interpro:IPR036291|reactome:R-SCE-1483166|sgd:YOL059W(identity)	-	crc64:609B121DA1A9DCB8	crc64:FA6C07034D3EC720	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:N/GPJUGBK+Dh5Cg+csmafphuo9M9606	rogid:RX8TddHnpQdQdh6KN8y9IR8Jgrg559292	intact-crc:D42DF27328FF661E|rigid:3CRaXf3nmzXRGwe6e1gllePohpw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12800	uniprotkb:P41902	intact:EBI-717422|uniprotkb:Q12801|uniprotkb:Q9UD77|uniprotkb:A8K5E9|uniprotkb:Q9UD75|ensembl:ENSP00000257915	intact:EBI-5162|uniprotkb:D6W296	psi-mi:tfcp2_human(display_long)|uniprotkb:Transcription factor LSF(gene name synonym)|uniprotkb:SAA3 enhancer factor(gene name synonym)|uniprotkb:TFCP2(gene name)|psi-mi:TFCP2(display_short)|uniprotkb:LSF(gene name synonym)|uniprotkb:SEF(gene name synonym)	psi-mi:crs5_yeast(display_long)|uniprotkb:CRS5(gene name)|psi-mi:CRS5(display_short)|uniprotkb:O2675(orf name)|uniprotkb:YOR031W(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11542251|imex:IM-24995-2098	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001166923.1|refseq:NP_001166924.1|refseq:NP_005644.2|ensembl:ENSG00000135457(gene)|ensembl:ENST00000257915(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR007604(CP2 transcription factor)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR037599|interpro:IPR041418|mint:Q12800|entrezgene/locuslink:7024(identity)	sgd:S000005557|dip:DIP-5511N|go:"GO:0005507"(copper ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0010038"(response to metal ion)|interpro:IPR035715|sgd:YOR031W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:M7mQ08NDYxuawmUEKRgjSdIr+Og9606	rogid:j4oJEwGSOVJeLFRydjF0k9ASq14559292	intact-crc:6973175F185632A4|rigid:Ptae9zJfdvTrIUq6XDJvdTnn7GM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40959	uniprotkb:O43791	intact:EBI-11636|ensemblfungi:YMR004W|uniprotkb:D6VZH9	intact:EBI-743549|uniprotkb:Q53HJ1|uniprotkb:B2R6S3|uniprotkb:D3DTW7|ensembl:ENSP00000240327|ensembl:ENSP00000377001|ensembl:ENSP00000420908|ensembl:ENSP00000424119|ensembl:ENSP00000425905|ensembl:ENSP00000426986|ensembl:ENSP00000499562	psi-mi:mvp1_yeast(display_long)|uniprotkb:MVP1(gene name)|psi-mi:MVP1(display_short)|uniprotkb:YM8270.06(orf name)|uniprotkb:YMR004W(locus name)	psi-mi:spop_human(display_long)|uniprotkb:HIB homolog 1(gene name synonym)|uniprotkb:Roadkill homolog 1(gene name synonym)|uniprotkb:SPOP(gene name)|psi-mi:SPOP(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11542242|imex:IM-24995-2097	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YMR004W(gene)|ensemblfungi:YMR004W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0016020"(membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0097320"(plasma membrane tubulation)|interpro:IPR001683(Phox-like)|interpro:IPR028662|interpro:IPR035704|interpro:IPR036871|rcsb pdb:6Q0X|refseq:NP_013717.1|sgd:S000004606|mint:P40959|dip:DIP-1764N|sgd:YMR004W(identity)	refseq:NP_001007227.1|refseq:NP_001007228.1|refseq:NP_001007229.1|refseq:NP_001007230.1|refseq:NP_001007231.1|refseq:NP_003554.1|refseq:XP_005257780.1|refseq:XP_005257781.1|ensembl:ENSG00000121067(gene)|ensembl:ENST00000347630(transcript)|ensembl:ENST00000393328(transcript)|ensembl:ENST00000503676(transcript)|ensembl:ENST00000504102(transcript)|ensembl:ENST00000509079(transcript)|ensembl:ENST00000514121(transcript)|ensembl:ENST00000665825(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0016607"(nuclear speck)|go:"GO:0030162"(regulation of proteolysis)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR034089|mint:O43791|rcsb pdb:2CR2|rcsb pdb:3HQH|rcsb pdb:3HQI|rcsb pdb:3HQL|rcsb pdb:3HQM|rcsb pdb:3HSV|rcsb pdb:3HTM|rcsb pdb:3HU6|rcsb pdb:3IVB|rcsb pdb:3IVQ|rcsb pdb:3IVV|rcsb pdb:4EOZ|rcsb pdb:4HS2|rcsb pdb:4J8Z|rcsb pdb:4O1V|rcsb pdb:6F8F|rcsb pdb:6F8G|rcsb pdb:6I41|rcsb pdb:6I5P|rcsb pdb:6I68|rcsb pdb:6I7A|rcsb pdb:7D3D|rcsb pdb:7LIN|rcsb pdb:7LIO|rcsb pdb:7LIP|rcsb pdb:7LIQ|reactome:R-HSA-5632684|go:"GO:0005634"(nucleus)|refseq:XP_016880693.1|dip:DIP-50517N|entrezgene/locuslink:8405(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:3IrMPCYXP5yb2l52Uhu2DiEuNdI559292	rogid:PC9ofpvk14xwTnnqT590/YRnx/49606	intact-crc:E23C3527845603CC|rigid:W0IEqqkqzN/r9Rp/S5G9rR8DnFc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40958	uniprotkb:Q5JR59-3	intact:EBI-10362|ensemblfungi:YJL030W|uniprotkb:D6VWF2	intact:EBI-11522433|ensembl:ENSP00000370186	psi-mi:mad2_yeast(display_long)|uniprotkb:MAD2(gene name)|psi-mi:MAD2(display_short)|uniprotkb:J1256(orf name)|uniprotkb:YJL030W(locus name)	psi-mi:q5jr59-3(display_long)|uniprotkb:MTUS2(gene name)|psi-mi:MTUS2(display_short)|uniprotkb:CAZIP(gene name synonym)|uniprotkb:Cardiac zipper protein(gene name synonym)|uniprotkb:KIAA0774(gene name synonym)|uniprotkb:Microtubule plus-end tracking protein TIP150(gene name synonym)|uniprotkb:TIP150(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11542233|imex:IM-24995-2096	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003567|ensemblfungi:YJL030W(gene)|ensemblfungi:YJL030W_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0033597"(mitotic checkpoint complex)|go:"GO:0044774"(mitotic DNA integrity checkpoint signaling)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051301"(cell division)|go:"GO:0051312"(chromosome decondensation)|go:"GO:1902499"(positive regulation of protein autoubiquitination)|interpro:IPR003511(DNA-binding HORMA)|interpro:IPR027097|interpro:IPR036570|reactome:R-SCE-141405|reactome:R-SCE-141430|refseq:NP_012504.3|dip:DIP-815N|mint:P40958|sgd:YJL030W(identity)	ensembl:ENSG00000132938(gene)|ensembl:ENST00000380808(transcript)|intact:EBI-742948(isoform-parent)|uniprotkb:Q5JR59-3(isoform-parent)|entrezgene/locuslink:23281(identity)	-	-	isoform-comment:No experimental confirmation available.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:0pxFckODTcklkGn+JcczltjSHRU559292	rogid:npId9tC7VoLN/jteoBiRbSYChPs9606	intact-crc:A22140B78F8C5D99|rigid:GcG2aYAqQEdnpQZa1GwLlJzofBc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40956	uniprotkb:Q9NRA8-2	intact:EBI-7968|uniprotkb:D6VTX2|ensemblfungi:YGL181W	intact:EBI-11531709|ensembl:ENSP00000342927	psi-mi:gts1_yeast(display_long)|uniprotkb:YGL181W(locus name)|uniprotkb:GTS1(gene name)|psi-mi:GTS1(display_short)|uniprotkb:LSR1(gene name synonym)|uniprotkb:Protein LSR1(gene name synonym)	psi-mi:q9nra8-2(display_long)|uniprotkb:Eukaryotic translation initiation factor 4E nuclear import factor 1(gene name synonym)|uniprotkb:EIF4ENIF1(gene name)|psi-mi:EIF4ENIF1(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11542224|imex:IM-24995-2095	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011334.1|sgd:S000003149|mint:P40956|dip:DIP-2746N|ensemblfungi:YGL181W(gene)|ensemblfungi:YGL181W_mRNA(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0006897"(endocytosis)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010512"(negative regulation of phosphatidylinositol biosynthetic process)|go:"GO:0030479"(actin cortical patch)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR037278|interpro:IPR038508|sgd:YGL181W(identity)	ensembl:ENSG00000184708(gene)|ensembl:ENST00000344710(transcript)|intact:EBI-301024(isoform-parent)|uniprotkb:Q9NRA8-2(isoform-parent)|entrezgene/locuslink:56478(identity)	-	crc64:D687E3BF6B620795	isoform-comment:No experimental confirmation available.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:8kgpssCRrHiTHsFaOH2nDK6EIjk559292	rogid:VQghhcptYh8k783QTJChpGbP/lU9606	intact-crc:BC219FB0A51E87FF|rigid:WE2+SYyQQcCNUzCbGUz+wCkFZFo	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9NRA8	uniprotkb:P40956	intact:EBI-301024|uniprotkb:B1AKL2|uniprotkb:Q8NCF2|uniprotkb:Q9H708|uniprotkb:B2RBF1|ensembl:ENSP00000328103|ensembl:ENSP00000380659|intact:EBI-877635|uniprotkb:B1AKL3	intact:EBI-7968|uniprotkb:D6VTX2|ensemblfungi:YGL181W	psi-mi:4et_human(display_long)|uniprotkb:EIF4ENIF1(gene name)|psi-mi:EIF4ENIF1(display_short)|uniprotkb:Eukaryotic translation initiation factor 4E nuclear import factor 1(gene name synonym)	psi-mi:gts1_yeast(display_long)|uniprotkb:YGL181W(locus name)|uniprotkb:GTS1(gene name)|psi-mi:GTS1(display_short)|uniprotkb:LSR1(gene name synonym)|uniprotkb:Protein LSR1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11542215|imex:IM-24995-2094	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000328103|ensembl:ENST00000344710|ensembl:ENSP00000342927|ensembl:ENSP00000380659|ensembl:ENSG00000184708(gene)|ensembl:ENST00000330125(transcript)|ensembl:ENST00000397525(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0016020"(membrane)|go:"GO:0016605"(PML body)|go:"GO:0016607"(nuclear speck)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019900"(kinase binding)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0033962"(P-body assembly)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0106289"(negative regulation of deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:1905618"(positive regulation of miRNA-mediated gene silencing by inhibition of translation)|interpro:IPR018862|mint:Q9NRA8|rcsb pdb:5ANR|rcsb pdb:6F9W|rcsb pdb:6X2R|refseq:NP_001157973.1|refseq:NP_001157974.1|refseq:NP_062817.2|refseq:XP_011528582.1|refseq:XP_011528583.1|refseq:XP_005261743.1|refseq:XP_005261744.1|refseq:XP_005261745.1|refseq:XP_016884353.1|entrezgene/locuslink:56478(identity)	refseq:NP_011334.1|sgd:S000003149|mint:P40956|dip:DIP-2746N|ensemblfungi:YGL181W(gene)|ensemblfungi:YGL181W_mRNA(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0006897"(endocytosis)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010512"(negative regulation of phosphatidylinositol biosynthetic process)|go:"GO:0030479"(actin cortical patch)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR037278|interpro:IPR038508|sgd:YGL181W(identity)	-	-	crc64:D687E3BF6B620795	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:4A9mF81S/ePAraruTNYgovUdkT49606	rogid:8kgpssCRrHiTHsFaOH2nDK6EIjk559292	intact-crc:D1B8AEE66174DBE9|rigid:M4JgLF5EA5zU5iL3Fn5trsEiHac	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40956	uniprotkb:Q9NP66	intact:EBI-7968|uniprotkb:D6VTX2|ensemblfungi:YGL181W	intact:EBI-740641|ensembl:ENSP00000336856|ensembl:ENSP00000371133|uniprotkb:A6NHY3|uniprotkb:Q53G31|uniprotkb:Q9NSF6|uniprotkb:D3DW78	psi-mi:gts1_yeast(display_long)|uniprotkb:YGL181W(locus name)|uniprotkb:GTS1(gene name)|psi-mi:GTS1(display_short)|uniprotkb:LSR1(gene name synonym)|uniprotkb:Protein LSR1(gene name synonym)	psi-mi:hm20a_human(display_long)|uniprotkb:HMG box-containing protein 20A(gene name synonym)|uniprotkb:HMG domain-containing protein HMGX1(gene name synonym)|uniprotkb:HMG20A(gene name)|psi-mi:HMG20A(display_short)|uniprotkb:HMGX1(gene name synonym)|uniprotkb:HMGXB1(gene name synonym)|uniprotkb:HMG domain-containing protein 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11542206|imex:IM-24995-2093	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011334.1|sgd:S000003149|mint:P40956|dip:DIP-2746N|ensemblfungi:YGL181W(gene)|ensemblfungi:YGL181W_mRNA(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0006897"(endocytosis)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010512"(negative regulation of phosphatidylinositol biosynthetic process)|go:"GO:0030479"(actin cortical patch)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR037278|interpro:IPR038508|sgd:YGL181W(identity)	refseq:NP_060670.1|ensembl:ENSG00000140382(gene)|ensembl:ENST00000336216(transcript)|ensembl:ENST00000381714(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0033234"(negative regulation of protein sumoylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045665"(negative regulation of neuron differentiation)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR036910|mint:Q9NP66|refseq:NP_001291433.1|refseq:NP_001291434.1|refseq:XP_011519460.1|entrezgene/locuslink:10363(identity)	-	crc64:D687E3BF6B620795	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:8kgpssCRrHiTHsFaOH2nDK6EIjk559292	rogid:LhilayeP+xv97pbYzIA8yMvwUbc9606	intact-crc:15FF030260959D84|rigid:KFGEdcORXXfJ143rC9druKM9Cf8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P43556	uniprotkb:Q8WW24	intact:EBI-22845|uniprotkb:D6VTI3|ensemblfungi:YFL047W	intact:EBI-750487|ensembl:ENSP00000295201	psi-mi:rgd2_yeast(display_long)|uniprotkb:RGD2(gene name)|psi-mi:RGD2(display_short)|uniprotkb:YFL047W(locus name)	psi-mi:tekt4_human(display_long)|uniprotkb:TEKT4(gene name)|psi-mi:TEKT4(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11542355|imex:IM-24995-2109	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_428268.1|sgd:S000001847|dip:DIP-4958N|mint:P43556|go:"GO:0005935"(cellular bud neck)|interpro:IPR031160|reactome:R-SCE-8856828|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0032153"(cell division site)|interpro:IPR000198(RhoGAP)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR027267|ensemblfungi:YFL047W(gene)|ensemblfungi:YFL047W_mRNA(transcript)|go:"GO:0000935"(division septum)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005934"(cellular bud tip)|sgd:YFL047W(identity)	refseq:NP_653306.1|ensembl:ENSG00000163060(gene)|ensembl:ENST00000295201(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0036126"(sperm flagellum)|go:"GO:0060271"(cilium assembly)|go:"GO:0060294"(cilium movement involved in cell motility)|interpro:IPR000435(Tektin)|entrezgene/locuslink:150483(identity)	-	crc64:52CF174C5F650157	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:TaphLAmYObi9RXMbE2tJDrHtVxA559292	rogid:uSPBMKPN9VTr6rsdxgUPpfWynIA9606	intact-crc:6FB9039C794ED430|rigid:W5rR4lur6RJr3g69DaeB1n63rxQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P43552	uniprotkb:P46379-2	intact:EBI-22855|uniprotkb:D6VTH9|ensemblfungi:YFL051C	intact:EBI-10988864|ensembl:ENSP00000211379|ensembl:ENSP00000365143|ensembl:ENSP00000372938|ensembl:ENSP00000372940|ensembl:ENSP00000389121|ensembl:ENSP00000410156|ensembl:ENSP00000412110|ensembl:ENSP00000413698	psi-mi:yff1_yeast(display_long)|uniprotkb:YFL051C(locus name)	psi-mi:p46379-2(display_long)|uniprotkb:BAG6(gene name)|psi-mi:BAG6(display_short)|uniprotkb:BAG family molecular chaperone regulator 6(gene name synonym)|uniprotkb:BAT3(gene name synonym)|uniprotkb:BCL2-associated athanogene 6(gene name synonym)|uniprotkb:G3(gene name synonym)|uniprotkb:HLA-B-associated transcript 3(gene name synonym)|uniprotkb:Protein G3(gene name synonym)|uniprotkb:Protein Scythe(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11542346|imex:IM-24995-2108	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_116576.1|sgd:S000001843|dip:DIP-4270N|ensemblfungi:YFL051C(gene)|ensemblfungi:YFL051C_mRNA(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|sgd:YFL051C(identity)	intact:EBI-347552(isoform-parent)|uniprotkb:P46379-2(isoform-parent)|ensembl:ENSG00000096155(gene)|ensembl:ENSG00000204463(gene)|ensembl:ENSG00000229524(gene)|ensembl:ENSG00000233348(gene)|ensembl:ENST00000211379(transcript)|ensembl:ENST00000375976(transcript)|ensembl:ENST00000383446(transcript)|ensembl:ENST00000383448(transcript)|ensembl:ENST00000417144(transcript)|ensembl:ENST00000419847(transcript)|ensembl:ENST00000442479(transcript)|ensembl:ENST00000443182(transcript)|entrezgene/locuslink:7917(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:oiB9m73Dyv5h04x667Dlwx3MiC8559292	rogid:7y9hxqfcTmnCBRON6qNoHPCdODY9606	intact-crc:AD028A0E372166E0|rigid:1YisNh/uvaM61W64I65X41K4b1E	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P42947	uniprotkb:Q99750	intact:EBI-26023|uniprotkb:D6VW77|ensemblfungi:YJL107C	intact:EBI-724076|ensembl:ENSP00000230321|ensembl:ENSP00000362142	psi-mi:yjk7_yeast(display_long)|uniprotkb:J0813(orf name)|uniprotkb:YJL107C(locus name)	psi-mi:mdfi_human(display_long)|uniprotkb:Myogenic repressor I-mf(gene name synonym)|uniprotkb:MDFI(gene name)|psi-mi:MDFI(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11542337|imex:IM-24995-2107	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003643|refseq:NP_012428.1|mint:P42947|dip:DIP-5095N|ensemblfungi:YJL107C(gene)|ensemblfungi:YJL107C_mRNA(transcript)|interpro:IPR010619(Protein of unknown function DUF1212)|sgd:YJL107C(identity)	refseq:NP_005577.1|ensembl:ENSG00000112559(gene)|ensembl:ENST00000230321(transcript)|ensembl:ENST00000373051(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR026134|mint:Q99750|refseq:NP_001287733.1|refseq:NP_001287734.1|refseq:NP_001287735.1|entrezgene/locuslink:4188(identity)	-	crc64:D7659D1955F5677F	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:U2SdxE3xuNnsKGX/4Gb0dpB6M+w559292	rogid:V3vU0fihMOW18DMHAiDbuZ3asNU9606	intact-crc:5C68B770D049F1AB|rigid:SfauxaIjEe1YZMuZdEusbsmH1v8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P42944	uniprotkb:Q08379	intact:EBI-8042|uniprotkb:D6VW74|ensemblfungi:YJL110C	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	psi-mi:gzf3_yeast(display_long)|uniprotkb:GZF3(gene name)|psi-mi:GZF3(display_short)|uniprotkb:J0806(orf name)|uniprotkb:YJL110C(locus name)	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11542326|imex:IM-24995-2106	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012425.1|sgd:S000003646|mint:P42944|dip:DIP-1359N|ensemblfungi:YJL110C(gene)|ensemblfungi:YJL110C_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0090295"(nitrogen catabolite repression of transcription)|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR039355|reactome:R-SCE-9018519|sgd:YJL110C(identity)	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N|entrezgene/locuslink:2801(identity)	-	crc64:807243799BFAB704	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2017/05/26	rogid:HOMBFcxVuABRuzPHcnDG87+R6sQ559292	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	intact-crc:B6973946DC431D39|rigid:6LN/DmegS/tGLsg5/MUSFS6ztsk	false	-	sufficient binding region:383-1002	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UFD9	uniprotkb:P42937	intact:EBI-10182375|uniprotkb:Q9UFQ5|uniprotkb:Q8IYP7|uniprotkb:Q9BY94|intact:EBI-28984856|ensembl:ENSP00000483386	intact:EBI-23470|uniprotkb:D6VUY5|ensemblfungi:YGR203W	psi-mi:rim3a_human(display_long)|uniprotkb:RIMBP3(gene name)|psi-mi:RIMBP3(display_short)|uniprotkb:KIAA1666(gene name synonym)|uniprotkb:RIMBP3A(gene name synonym)|uniprotkb:RIMS-binding protein 3.1(gene name synonym)	psi-mi:ych1_yeast(display_long)|uniprotkb:YGR203W(locus name)|uniprotkb:G7731(orf name)|uniprotkb:YCH1(gene name)|psi-mi:YCH1(display_short)|uniprotkb:CDC25 homolog 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11542315|imex:IM-24995-2105	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_056487.1|ensembl:ENSP00000483386|ensembl:ENSG00000275793(gene)|ensembl:ENST00000619918(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007286"(spermatid development)|go:"GO:0009566"(fertilization)|go:"GO:0030156"(benzodiazepine receptor binding)|go:"GO:0045202"(synapse)|interpro:IPR001452(Src homology-3)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR035515|interpro:IPR036028|interpro:IPR036116|interpro:IPR040325|rcsb pdb:2EGE|entrezgene/locuslink:85376(identity)	refseq:NP_011719.1|sgd:S000003435|dip:DIP-885N|ensemblfungi:YGR203W(gene)|ensemblfungi:YGR203W_mRNA(transcript)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0004792"(thiosulfate sulfurtransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016311"(dephosphorylation)|go:"GO:0016791"(phosphatase activity)|interpro:IPR001763(Rhodanese-like)|interpro:IPR036873|rcsb pdb:3F4A|rcsb pdb:3FS5|sgd:YGR203W(identity)	-	-	crc64:41527DB282CBFF11	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:iw34Gee4nqAH3pqUfCgQ6Jj++AA9606	rogid:p8SYf/V7HMF1NdntyAYkfOBvlPk559292	intact-crc:256D00598A3828E6|rigid:9l31IlXMhzvSc+WdrwcdhX/6RaY	false	sufficient binding region:838-1639	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P42937	uniprotkb:Q8N5R6	intact:EBI-23470|uniprotkb:D6VUY5|ensemblfungi:YGR203W	intact:EBI-740841|intact:EBI-953781|uniprotkb:B3KQ49|uniprotkb:A8K3U4|uniprotkb:A8MPQ6|uniprotkb:A8MV61|uniprotkb:A8MVU9|uniprotkb:Q9H5Q6|uniprotkb:Q8TAX6|intact:EBI-2320546|intact:EBI-11522976	psi-mi:ych1_yeast(display_long)|uniprotkb:YGR203W(locus name)|uniprotkb:G7731(orf name)|uniprotkb:YCH1(gene name)|psi-mi:YCH1(display_short)|uniprotkb:CDC25 homolog 1(gene name synonym)	psi-mi:ccd33_human(display_long)|uniprotkb:CCDC33(gene name)|psi-mi:CCDC33(display_short)|uniprotkb:Cancer/testis antigen 61(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11542306|imex:IM-24995-2104	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011719.1|sgd:S000003435|dip:DIP-885N|ensemblfungi:YGR203W(gene)|ensemblfungi:YGR203W_mRNA(transcript)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0004792"(thiosulfate sulfurtransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016311"(dephosphorylation)|go:"GO:0016791"(phosphatase activity)|interpro:IPR001763(Rhodanese-like)|interpro:IPR036873|rcsb pdb:3F4A|rcsb pdb:3FS5|sgd:YGR203W(identity)	refseq:NP_079331.3|interpro:IPR000008(C2 calcium-dependent membrane targeting)|go:"GO:0005777"(peroxisome)|refseq:NP_001274110.1|refseq:NP_877592.2|mint:Q8N5R6|interpro:IPR035892|interpro:IPR039889|entrezgene/locuslink:80125(identity)	-	crc64:41527DB282CBFF11	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2021/11/30	rogid:p8SYf/V7HMF1NdntyAYkfOBvlPk559292	rogid:eEIn7pQyfdHWx8TeLJpYy0i/gww9606	intact-crc:4861B2BFD5C3B4E3|rigid:+vXoUJGEq5t7Gf9Xfd8nxl0T6uM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9H190	uniprotkb:P42846	intact:EBI-742426|ensembl:ENSP00000371233|uniprotkb:O95892|uniprotkb:Q5W0X1|uniprotkb:Q9BZ42|uniprotkb:Q9H567|uniprotkb:Q9NRY8|intact:EBI-28983470|ensembl:ENSP00000342935|ensembl:ENSP00000354013	intact:EBI-28360|uniprotkb:D6W0N7|ensemblfungi:YNL308C	psi-mi:sdcb2_human(display_long)|uniprotkb:Similar to TACIP18(gene name synonym)|uniprotkb:SDCBP2(gene name)|psi-mi:SDCBP2(display_short)|uniprotkb:SITAC18(gene name synonym)|uniprotkb:Syndecan-binding protein 2(gene name synonym)	psi-mi:kri1_yeast(display_long)|uniprotkb:YNL308C(locus name)|uniprotkb:N0388(orf name)|uniprotkb:KRR1-interacting protein 1(gene name synonym)|uniprotkb:KRI1(gene name)|psi-mi:KRI1(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11542297|imex:IM-24995-2103	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001186713.1|refseq:NP_056500.2|refseq:NP_536737.3|ensembl:ENSP00000342935|ensembl:ENSP00000354013|ensembl:ENST00000381808|ensembl:ENSP00000371229|ensembl:ENSP00000371233|ensembl:ENSG00000125775(gene)|ensembl:ENST00000360779(transcript)|ensembl:ENST00000381812(transcript)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007399"(nervous system development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016607"(nuclear speck)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046907"(intracellular transport)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036034|interpro:IPR041489|ensembl:ENST00000339987(transcript)|entrezgene/locuslink:27111(identity)	refseq:NP_014091.1|sgd:S000005252|dip:DIP-4073N|mint:P42846|ensemblfungi:YNL308C(gene)|ensemblfungi:YNL308C_mRNA(transcript)|go:"GO:0000447"("endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0005730"(nucleolus)|go:"GO:0030686"(90S preribosome)|interpro:IPR018034|interpro:IPR024626|sgd:YNL308C(identity)	-	-	crc64:3B637571EDB05EA6	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:vlEtVZkwLTte5PJ4i8ce+SwE/4Y9606	rogid:NhrYBQD07sx7vTVgiDFulg1FrAI559292	intact-crc:A8CB67C875BB1E8B|rigid:7fCfnus8xIBHPRTPaAKnPuow3RE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P43588	uniprotkb:Q9GZT8	intact:EBI-11219|uniprotkb:Q8J0T5|uniprotkb:D6VTN4|ensemblfungi:YFR004W	intact:EBI-740897|uniprotkb:Q9H2D2|uniprotkb:Q9HC18|uniprotkb:Q6X735|uniprotkb:Q53TX4|ensembl:ENSP00000386394|ensembl:ENSP00000387315|ensembl:ENSP00000498853	psi-mi:rpn11_yeast(display_long)|uniprotkb:YFR004W(locus name)|uniprotkb:RPN11(gene name)|psi-mi:RPN11(display_short)|uniprotkb:MPR1(gene name synonym)|uniprotkb:Protein MPR1(gene name synonym)|uniprotkb:26S proteasome regulatory subunit RPN11(gene name synonym)	psi-mi:nif3l_human(display_long)|uniprotkb:Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 1 protein(gene name synonym)|uniprotkb:MDS015(orf name)|uniprotkb:My018(orf name)|uniprotkb:NIF3L1(gene name)|psi-mi:NIF3L1(display_short)|uniprotkb:ALS2CR1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11542385|imex:IM-24995-2112	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YFR004W(gene)|ensemblfungi:YFR004W_mRNA(transcript)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0016559"(peroxisome fission)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043248"(proteasome assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0061578"(Lys63-specific deubiquitinase activity)|go:"GO:0070628"(proteasome binding)|go:"GO:1902906"(proteasome storage granule assembly)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR024969|interpro:IPR035299|interpro:IPR037518|rcsb pdb:3J47|rcsb pdb:3JCK|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:4O8X|rcsb pdb:4O8Y|rcsb pdb:4OCL|rcsb pdb:4OCM|go:"GO:0070122"(isopeptidase activity)|rcsb pdb:4OCN|rcsb pdb:4OWP|rcsb pdb:5A5B|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5MPD|rcsb pdb:5MPE|rcsb pdb:5U4P|rcsb pdb:5W83|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-5689901|reactome:R-SCE-6798695|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|refseq:NP_116659.1|sgd:S000001900|mint:P43588|dip:DIP-1573N|sgd:YFR004W(identity)	refseq:NP_001129511.1|refseq:NP_001135827.1|refseq:NP_068596.2|refseq:XP_011509887.1|refseq:XP_011509884.1|refseq:XP_011509885.1|refseq:XP_011509886.1|refseq:NP_001135828.1|refseq:XP_005246799.1|refseq:XP_016860119.1|ensembl:ENSG00000196290(gene)|ensembl:ENST00000409020(transcript)|ensembl:ENST00000409357(transcript)|ensembl:ENST00000651500(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:1903507"(negative regulation of nucleic acid-templated transcription)|interpro:IPR002678(NGG1p interacting factor 3, NIF3)|interpro:IPR017222(Uncharacterised conserved protein UCP037490, NIF3, eukaryota)|interpro:IPR036069|mint:Q9GZT8|entrezgene/locuslink:60491(identity)	-	crc64:9DDE8BD74890894D	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:f3lAMY9siMcO2dAOfKvVrvKzfNM559292	rogid:Vvyb7CJpcwGtGAVKT2Zoqycr2yQ9606	intact-crc:C6E9CFF81D927E4E|rigid:8KKyIvG5++kvD+nzm1lq/NQVyMQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P43569	uniprotkb:O43639	intact:EBI-22808|uniprotkb:D6VTK2|ensemblfungi:YFL028C	intact:EBI-713635|uniprotkb:Q9BWN9|uniprotkb:Q9UIC3|ensembl:ENSP00000233154|ensembl:ENSP00000377018|uniprotkb:D3DVK1	psi-mi:caf16_yeast(display_long)|uniprotkb:CAF16(gene name)|psi-mi:CAF16(display_short)|uniprotkb:YFL028C(locus name)	psi-mi:nck2_human(display_long)|uniprotkb:NCK adaptor protein 2(gene name synonym)|uniprotkb:SH2/SH3 adaptor protein NCK-beta(gene name synonym)|uniprotkb:NCK2(gene name)|psi-mi:NCK2(display_short)|uniprotkb:GRB4(gene name synonym)|uniprotkb:Growth factor receptor-bound protein 4(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11542376|imex:IM-24995-2111	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_116625.1|sgd:S000001866|dip:DIP-5946N|ensemblfungi:YFL028C(gene)|ensemblfungi:YFL028C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0030014"(CCR4-NOT complex)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR027417|sgd:YFL028C(identity)	refseq:XP_006712860.1|refseq:NP_001004720.1|refseq:NP_003572.2|ensembl:ENSG00000071051(gene)|ensembl:ENST00000233154(transcript)|ensembl:ENST00000393349(transcript)|go:"GO:0001771"(immunological synapse formation)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0007015"(actin filament organization)|go:"GO:0007165"(signal transduction)|go:"GO:0007172"(signal complex assembly)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007176"(regulation of epidermal growth factor-activated receptor activity)|go:"GO:0008093"(cytoskeletal anchor activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0012506"(vesicle membrane)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016477"(cell migration)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0036493"(positive regulation of translation in response to endoplasmic reticulum stress)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042110"(T cell activation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0060996"(dendritic spine development)|go:"GO:0097110"(scaffold protein binding)|go:"GO:1902237"(positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903898"(negative regulation of PERK-mediated unfolded protein response)|go:"GO:1903912"(negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation)|go:"GO:1990441"(negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR017304(Cytoplasmic, NCK)|interpro:IPR028524|interpro:IPR035559|interpro:IPR035560|interpro:IPR035561|interpro:IPR035883|interpro:IPR036028|interpro:IPR036860|mint:O43639|rcsb pdb:1U5S|rcsb pdb:1WX6|rcsb pdb:1Z3K|rcsb pdb:2B86|rcsb pdb:2CIA|rcsb pdb:2FRW|rcsb pdb:2FRY|rcsb pdb:2JXB|rcsb pdb:4E6R|reactome:R-HSA-186763|reactome:R-HSA-373753|reactome:R-HSA-3928664|reactome:R-HSA-428540|reactome:R-HSA-4420097|reactome:R-HSA-8985801|reactome:R-HSA-9013420|reactome:R-HSA-9013424|refseq:XP_016860592.1|refseq:XP_016860593.1|refseq:XP_016860594.1|refseq:XP_011510293.1|entrezgene/locuslink:8440(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:TEaj2ClpUSgtlaILtvQi9v5zB6A559292	rogid:WV9nJ78Im/ga5KQlRuSN2ODzWpQ9606	intact-crc:C02EBA6BDBAF641C|rigid:GAqQ92YJyTpMzbs4uDUGVOhHZZ0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UJ70-2	uniprotkb:P43556	intact:EBI-11526455|ensembl:ENSP00000389087|ensembl:ENSP00000477639	intact:EBI-22845|uniprotkb:D6VTI3|ensemblfungi:YFL047W	psi-mi:q9uj70-2(display_long)|uniprotkb:GlcNAc kinase(gene name synonym)|uniprotkb:NAGK(gene name)|psi-mi:NAGK(display_short)	psi-mi:rgd2_yeast(display_long)|uniprotkb:RGD2(gene name)|psi-mi:RGD2(display_short)|uniprotkb:YFL047W(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11542364|imex:IM-24995-2110	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-372578(isoform-parent)|ensembl:ENSG00000124357(gene)|ensembl:ENST00000455662(transcript)|ensembl:ENST00000613852(transcript)|uniprotkb:Q9UJ70-2(isoform-parent)|entrezgene/locuslink:55577(identity)	refseq:NP_428268.1|sgd:S000001847|dip:DIP-4958N|mint:P43556|go:"GO:0005935"(cellular bud neck)|interpro:IPR031160|reactome:R-SCE-8856828|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0032153"(cell division site)|interpro:IPR000198(RhoGAP)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR027267|ensemblfungi:YFL047W(gene)|ensemblfungi:YFL047W_mRNA(transcript)|go:"GO:0000935"(division septum)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005934"(cellular bud tip)|sgd:YFL047W(identity)	-	-	crc64:52CF174C5F650157	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:zoy4C+HK341UnmDRUlMuJucczr89606	rogid:TaphLAmYObi9RXMbE2tJDrHtVxA559292	intact-crc:D787DD32F2F87B71|rigid:7yBeKNZ0uHkUv4s/ch83jqe0tK4	false	sufficient binding region:47-390	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P46678	uniprotkb:Q9UL45	intact:EBI-19164|uniprotkb:D6W1E0|ensemblfungi:YNL039W	intact:EBI-465781|ensembl:ENSP00000220531	psi-mi:tfc5_yeast(display_long)|uniprotkb:TFIIIB90(gene name synonym)|uniprotkb:BDP1(gene name)|psi-mi:BDP1(display_short)|uniprotkb:TFC5(gene name synonym)|uniprotkb:YNL039W(locus name)|uniprotkb:N2682(orf name)	psi-mi:bl1s6_human(display_long)|uniprotkb:BLOC1S6(gene name)|psi-mi:BLOC1S6(display_short)|uniprotkb:PA(gene name synonym)|uniprotkb:PLDN(gene name synonym)|uniprotkb:Pallid protein homolog(gene name synonym)|uniprotkb:Pallidin(gene name synonym)|uniprotkb:Syntaxin 13-interacting protein(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11542439|imex:IM-24995-2118	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000004984|ensemblfungi:YNL039W(gene)|ensemblfungi:YNL039W_mRNA(transcript)|go:"GO:0000126"(transcription factor TFIIIB complex)|go:"GO:0000995"(RNA polymerase III general transcription initiation factor activity)|go:"GO:0001112"(DNA-templated transcription open complex formation)|go:"GO:0001156"(TFIIIC-class transcription factor complex binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0070896"(positive regulation of transposon integration)|go:"GO:0070898"(RNA polymerase III preinitiation complex assembly)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017174(Transcription factor IIIB, Bdp1 subunit, fungi)|interpro:IPR039467|rcsb pdb:6CNB|rcsb pdb:6CNC|rcsb pdb:6CND|rcsb pdb:6CNF|rcsb pdb:6EU0|rcsb pdb:6F40|rcsb pdb:6F41|rcsb pdb:6F42|rcsb pdb:6F44|reactome:R-SCE-76061|reactome:R-SCE-76066|refseq:NP_014359.3|dip:DIP-964N|mint:P46678|sgd:YNL039W(identity)	ensembl:ENSG00000104164(gene)|ensembl:ENST00000220531(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0007596"(blood coagulation)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0016081"(synaptic vesicle docking)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030133"(transport vesicle)|go:"GO:0030318"(melanocyte differentiation)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0032402"(melanosome transport)|go:"GO:0032438"(melanosome organization)|go:"GO:0032816"(positive regulation of natural killer cell activation)|go:"GO:0033299"(secretion of lysosomal enzymes)|go:"GO:0035646"(endosome to melanosome transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046907"(intracellular transport)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0050942"(positive regulation of pigment cell differentiation)|go:"GO:0051015"(actin filament binding)|go:"GO:0061025"(membrane fusion)|go:"GO:0098793"(presynapse)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR017242(BLOC-1 complex, pallidin subunit)|go:"GO:0031175"(neuron projection development)|interpro:IPR028119|mint:Q9UL45|reactome:R-HSA-432722|refseq:NP_036520.1|entrezgene/locuslink:26258(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:UHI3UvDK3qlouZn4JrhYcxOhr1s559292	rogid:s5/ikwpqtA8Mm8gMd6ttfmBBKSA9606	intact-crc:A0A90662FD4FA301|rigid:DTzuh9oFssqrZFkUaM1psx1rxzQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P46678	uniprotkb:Q9P1Z2	intact:EBI-19164|uniprotkb:D6W1E0|ensemblfungi:YNL039W	intact:EBI-749920|uniprotkb:B3KVA8|uniprotkb:Q6FI59|uniprotkb:Q71RC3|uniprotkb:Q86WF8|uniprotkb:Q96JU3|uniprotkb:Q9H090|intact:EBI-2558801|ensembl:ENSP00000449960	psi-mi:tfc5_yeast(display_long)|uniprotkb:TFIIIB90(gene name synonym)|uniprotkb:BDP1(gene name)|psi-mi:BDP1(display_short)|uniprotkb:TFC5(gene name synonym)|uniprotkb:YNL039W(locus name)|uniprotkb:N2682(orf name)	psi-mi:caco1_human(display_long)|uniprotkb:CALCOCO1(gene name)|psi-mi:CALCOCO1(display_short)|uniprotkb:KIAA1536(gene name synonym)|uniprotkb:Calphoglin(gene name synonym)|uniprotkb:Sarcoma antigen NY-SAR-3(gene name synonym)|uniprotkb:Coiled-coil coactivator protein(gene name synonym)|uniprotkb:PP13275(orf name)|uniprotkb:UNQ2436/PRO4996(orf name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11542430|imex:IM-24995-2117	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000004984|ensemblfungi:YNL039W(gene)|ensemblfungi:YNL039W_mRNA(transcript)|go:"GO:0000126"(transcription factor TFIIIB complex)|go:"GO:0000995"(RNA polymerase III general transcription initiation factor activity)|go:"GO:0001112"(DNA-templated transcription open complex formation)|go:"GO:0001156"(TFIIIC-class transcription factor complex binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0070896"(positive regulation of transposon integration)|go:"GO:0070898"(RNA polymerase III preinitiation complex assembly)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017174(Transcription factor IIIB, Bdp1 subunit, fungi)|interpro:IPR039467|rcsb pdb:6CNB|rcsb pdb:6CNC|rcsb pdb:6CND|rcsb pdb:6CNF|rcsb pdb:6EU0|rcsb pdb:6F40|rcsb pdb:6F41|rcsb pdb:6F42|rcsb pdb:6F44|reactome:R-SCE-76061|reactome:R-SCE-76066|refseq:NP_014359.3|dip:DIP-964N|mint:P46678|sgd:YNL039W(identity)	refseq:NP_001137154.1|refseq:NP_065949.1|refseq:XP_016875196.1|dip:DIP-47322N|ensembl:ENSG00000012822(gene)|ensembl:ENST00000550804(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0007165"(signal transduction)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0070016"(armadillo repeat domain binding)|interpro:IPR012852(Coiled-coil transcriptional coactivator-like)|interpro:IPR041611|interpro:IPR041641|mint:Q9P1Z2|entrezgene/locuslink:57658(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:UHI3UvDK3qlouZn4JrhYcxOhr1s559292	rogid:4M9Qyq+7GZ1w2UAN6k0ntGQNTvw9606	intact-crc:09349AEEC4C7DD66|rigid:jQCvoloeNiBRCXgyf7rudSND1Ws	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P43618	uniprotkb:O95198	intact:EBI-23036|uniprotkb:D6VTS9|uniprotkb:Q6B2K8|ensemblfungi:YFR046C	intact:EBI-746999|uniprotkb:B2RD18|uniprotkb:Q8N484|uniprotkb:Q8TBH5|uniprotkb:A6NCM7|uniprotkb:B4DFH7|uniprotkb:F5H6M3|ensembl:ENSP00000226725	psi-mi:cenpt_yeast(display_long)|uniprotkb:CNN1(gene name)|psi-mi:CNN1(display_short)|uniprotkb:Co-purified with NNF1 protein 1(gene name synonym)|uniprotkb:CENP-T homolog(gene name synonym)|uniprotkb:Constitutive centromere-associated network protein CNN1(gene name synonym)|uniprotkb:YFR046C(locus name)	psi-mi:klhl2_human(display_long)|uniprotkb:Actin-binding protein Mayven(gene name synonym)|uniprotkb:KLHL2(gene name)|psi-mi:KLHL2(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11542421|imex:IM-24995-2116	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000001942|refseq:NP_116704.1|dip:DIP-5186N|ensemblfungi:YFR046C(gene)|ensemblfungi:YFR046C_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0019237"(centromeric DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051301"(cell division)|go:"GO:1901720"(negative regulation of NMS complex assembly)|rcsb pdb:4GEQ|rcsb pdb:6WUC|rcsb pdb:6YPC|sgd:YFR046C(identity)	refseq:NP_001154993.1|refseq:NP_001154994.1|refseq:NP_009177.3|refseq:NP_001317952.1|refseq:NP_001317953.1|refseq:XP_016863165.1|ensembl:ENSG00000109466(gene)|ensembl:ENST00000226725(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030027"(lamellipodium)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR017096(Kelch-like protein, gigaxonin)|interpro:IPR044072|mint:O95198|rcsb pdb:2XN4|rcsb pdb:4CHB|reactome:R-HSA-8951664|reactome:R-HSA-983168|go:"GO:0042802"(identical protein binding)|entrezgene/locuslink:11275(identity)	-	crc64:48CEEC087A056D42	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Pkvt7uOWT2WqZlcWh8NeZH67Mvs559292	rogid:tFegR2lJZccRqs4qUjdT3PNjNnk9606	intact-crc:0178C35B4F6BFFF8|rigid:r9OW5JqnvYns5Kl5S88NI9Ly1nM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P43592	uniprotkb:Q8N6Y0	intact:EBI-22932|uniprotkb:D6VTN8|ensemblfungi:YFR008W	intact:EBI-739895|uniprotkb:Q8NBX7|uniprotkb:Q96KH3|uniprotkb:Q9BYI8|uniprotkb:A8K7L6|uniprotkb:B2RCR9|ensembl:ENSP00000252597	psi-mi:far7_yeast(display_long)|uniprotkb:YFR008W(locus name)|uniprotkb:FAR7(gene name)|psi-mi:FAR7(display_short)	psi-mi:usbp1_human(display_long)|uniprotkb:USHBP1(gene name)|psi-mi:USHBP1(display_short)|uniprotkb:MCC-2(gene name synonym)|uniprotkb:AIE-75-binding protein(gene name synonym)|uniprotkb:AIEBP(gene name synonym)|uniprotkb:MCC2(gene name synonym)|uniprotkb:Mutated in colon cancer protein 2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11542412|imex:IM-24995-2115	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000001904|refseq:NP_116663.1|dip:DIP-1315N|mint:P43592|ensemblfungi:YFR008W(gene)|ensemblfungi:YFR008W_mRNA(transcript)|go:"GO:0000321"(re-entry into mitotic cell cycle after pheromone arrest)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|sgd:YFR008W(identity)	refseq:NP_001284632.1|refseq:NP_114147.2|refseq:NP_001308346.1|ensembl:ENSG00000130307(gene)|ensembl:ENST00000252597(transcript)|go:"GO:0030165"(PDZ domain binding)|interpro:IPR019536|interpro:IPR040171|entrezgene/locuslink:83878(identity)	-	crc64:81156978FF7AAD54	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:RB7IaPAzOtEtryalHHz8psxOYqw559292	rogid:vY1qx73Ju/z7WDu6k1kd10ZDVRo9606	intact-crc:81AEB5BB241320FD|rigid:SHiwDECj2vArFtny+DqMP2mvmOI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P19012	uniprotkb:P43592	intact:EBI-739566|uniprotkb:Q53XV8|uniprotkb:Q9BUG4|uniprotkb:B3KQY1|uniprotkb:B3KRA2|uniprotkb:E0CX14|ensembl:ENSP00000254043|ensembl:ENSP00000377546	intact:EBI-22932|uniprotkb:D6VTN8|ensemblfungi:YFR008W	psi-mi:k1c15_human(display_long)|uniprotkb:KRT15(gene name)|psi-mi:KRT15(display_short)|uniprotkb:KRTB(gene name synonym)|uniprotkb:Cytokeratin-15(gene name synonym)|uniprotkb:Keratin-15(gene name synonym)	psi-mi:far7_yeast(display_long)|uniprotkb:YFR008W(locus name)|uniprotkb:FAR7(gene name)|psi-mi:FAR7(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11542403|imex:IM-24995-2114	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002266.2|ensembl:ENSG00000171346(gene)|ensembl:ENST00000254043(transcript)|ensembl:ENST00000393976(transcript)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0008544"(epidermis development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097110"(scaffold protein binding)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR039008|mint:P19012|reactome:R-HSA-6805567|reactome:R-HSA-6809371|entrezgene/locuslink:3866(identity)	sgd:S000001904|refseq:NP_116663.1|dip:DIP-1315N|mint:P43592|ensemblfungi:YFR008W(gene)|ensemblfungi:YFR008W_mRNA(transcript)|go:"GO:0000321"(re-entry into mitotic cell cycle after pheromone arrest)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|sgd:YFR008W(identity)	-	-	crc64:81156978FF7AAD54	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:WrZQBYQvrWcfrR5ojWXrXp6spPE9606	rogid:RB7IaPAzOtEtryalHHz8psxOYqw559292	intact-crc:A14CCADBB6873A16|rigid:iFW+ndIy4CRKN6qrfc80CuyYFAE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P43592	uniprotkb:O95751	intact:EBI-22932|uniprotkb:D6VTN8|ensemblfungi:YFR008W	intact:EBI-740738|ensembl:ENSP00000359557|uniprotkb:Q6IAR6	psi-mi:far7_yeast(display_long)|uniprotkb:YFR008W(locus name)|uniprotkb:FAR7(gene name)|psi-mi:FAR7(display_short)	psi-mi:ldoc1_human(display_long)|uniprotkb:Leucine zipper protein down-regulated in cancer cells(gene name synonym)|uniprotkb:LDOC1(gene name)|psi-mi:LDOC1(display_short)|uniprotkb:BCUR1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11542394|imex:IM-24995-2113	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000001904|refseq:NP_116663.1|dip:DIP-1315N|mint:P43592|ensemblfungi:YFR008W(gene)|ensemblfungi:YFR008W_mRNA(transcript)|go:"GO:0000321"(re-entry into mitotic cell cycle after pheromone arrest)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|sgd:YFR008W(identity)	refseq:NP_036449.1|ensembl:ENSG00000182195(gene)|ensembl:ENST00000370526(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071225"(cellular response to muramyl dipeptide)|interpro:IPR032549|interpro:IPR032567|entrezgene/locuslink:23641(identity)	-	crc64:81156978FF7AAD54	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:RB7IaPAzOtEtryalHHz8psxOYqw559292	rogid:Ediu0oNiZ/+YVY8l3fNdgP5A+v09606	intact-crc:C1725026741608B1|rigid:O7PdVOCZde1KYP3b4BIZbVVrlrE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P46945	uniprotkb:Q9UJV3-2	intact:EBI-11531997|uniprotkb:D6VTX6|ensemblfungi:YGL176C	intact:EBI-10172526|ensembl:ENSP00000413976	psi-mi:ygs6_yeast(display_long)|uniprotkb:G1636(orf name)|uniprotkb:YGL176C(locus name)	psi-mi:q9ujv3-2(display_long)|uniprotkb:RING-type E3 ubiquitin transferase MID2(gene name synonym)|uniprotkb:FXY2(gene name synonym)|uniprotkb:Midin-2(gene name synonym)|uniprotkb:Midline defect 2(gene name synonym)|uniprotkb:Midline-2(gene name synonym)|uniprotkb:RING finger protein 60(gene name synonym)|uniprotkb:RNF60(gene name synonym)|uniprotkb:TRIM1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 1(gene name synonym)|uniprotkb:MID2(gene name)|psi-mi:MID2(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11542504|imex:IM-24995-2125	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011339.1|sgd:S000003144|ensemblfungi:YGL176C(gene)|ensemblfungi:YGL176C_mRNA(transcript)|sgd:YGL176C(identity)	intact:EBI-751983(isoform-parent)|uniprotkb:Q9UJV3-2(isoform-parent)|ensembl:ENSG00000080561(gene)|ensembl:ENST00000443968(transcript)|entrezgene/locuslink:11043(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/03/16	rogid:vWpHYgTdiHjJQSg5gUHb94U3Uhk559292	rogid:/FJ+V2H7SaWon7caUWkEkmHFVxQ9606	intact-crc:31761077CBEEB5AB|rigid:eG8fkGozVkfJ5tFaS2KYEDcONnA	false	-	sufficient binding region:21-705	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P46682	uniprotkb:Q8NHQ1	intact:EBI-2213|uniprotkb:D6VV40|ensemblfungi:YGR261C	intact:EBI-739624|ensembl:ENSP00000264982|ensembl:ENSP00000419231|uniprotkb:Q96B31|uniprotkb:Q9H2C3|uniprotkb:Q9H2Z1|uniprotkb:Q9H940|uniprotkb:D3DNE9|uniprotkb:B7Z5I8|uniprotkb:B7Z7E8|uniprotkb:F5GZX8	psi-mi:ap3b_yeast(display_long)|uniprotkb:APL6(gene name)|psi-mi:APL6(display_short)|uniprotkb:YKS5(gene name synonym)|uniprotkb:YGR261C(locus name)|uniprotkb:G9331(orf name)|uniprotkb:Beta-3-adaptin(gene name synonym)|uniprotkb:Clathrin assembly protein complex 3 beta large chain(gene name synonym)|uniprotkb:Clathrin assembly protein large beta chain(gene name synonym)|uniprotkb:Adaptor-related protein complex 3 subunit beta(gene name synonym)	psi-mi:cep70_human(display_long)|uniprotkb:CEP70(gene name)|psi-mi:CEP70(display_short)|uniprotkb:BITE(gene name synonym)|uniprotkb:p10-binding protein(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11542495|imex:IM-24995-2124	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003493|refseq:NP_011777.3|ensemblfungi:YGR261C(gene)|ensemblfungi:YGR261C_mRNA(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030123"(AP-3 adaptor complex)|go:"GO:0030665"(clathrin-coated vesicle membrane)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026739|interpro:IPR026740|dip:DIP-2684N|mint:P46682|sgd:YGR261C(identity)	ensembl:ENSG00000114107(gene)|ensembl:ENST00000264982(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|interpro:IPR019734|interpro:IPR037692|mint:Q8NHQ1|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|ensembl:ENST00000484888(transcript)|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_077817.2|refseq:XP_016862764.1|refseq:NP_001275893.1|refseq:NP_001275894.1|refseq:NP_001275895.1|refseq:NP_001275896.1|refseq:NP_001307527.1|refseq:NP_001307529.1|entrezgene/locuslink:80321(identity)	-	crc64:475DA3A4F6E68E97	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:J+pCwMtq9Jhj24BeTVg7XpCHmKE559292	rogid:S4yveQWcvdVtAUX65gqrJ5Dv0Mc9606	intact-crc:61FA29D831761E44|rigid:M8Dkr3+t2NvMQ21DMTr7naSknDo	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P46682	uniprotkb:P61289	intact:EBI-2213|uniprotkb:D6VV40|ensemblfungi:YGR261C	intact:EBI-355546|uniprotkb:O35563|uniprotkb:P97373|uniprotkb:Q12920|uniprotkb:Q13172|uniprotkb:Q9BQD9|uniprotkb:A8K9A3|ensembl:ENSP00000466794	psi-mi:ap3b_yeast(display_long)|uniprotkb:APL6(gene name)|psi-mi:APL6(display_short)|uniprotkb:YKS5(gene name synonym)|uniprotkb:YGR261C(locus name)|uniprotkb:G9331(orf name)|uniprotkb:Beta-3-adaptin(gene name synonym)|uniprotkb:Clathrin assembly protein complex 3 beta large chain(gene name synonym)|uniprotkb:Clathrin assembly protein large beta chain(gene name synonym)|uniprotkb:Adaptor-related protein complex 3 subunit beta(gene name synonym)	psi-mi:psme3_human(display_long)|uniprotkb:PSME3(gene name)|psi-mi:PSME3(display_short)|uniprotkb:Proteasome activator 28 subunit gamma(gene name synonym)|uniprotkb:Activator of multicatalytic protease subunit 3(gene name synonym)|uniprotkb:11S regulator complex subunit gamma(gene name synonym)|uniprotkb:Ki nuclear autoantigen(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11542486|imex:IM-24995-2123	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003493|refseq:NP_011777.3|ensemblfungi:YGR261C(gene)|ensemblfungi:YGR261C_mRNA(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030123"(AP-3 adaptor complex)|go:"GO:0030665"(clathrin-coated vesicle membrane)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026739|interpro:IPR026740|dip:DIP-2684N|mint:P46682|sgd:YGR261C(identity)	refseq:NP_005780.2|refseq:NP_789839.1|ensembl:ENSG00000131467(gene)|ensembl:ENST00000590720(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0008537"(proteasome activator complex)|go:"GO:0010950"(positive regulation of endopeptidase activity)|go:"GO:0016020"(membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0061133"(endopeptidase activator activity)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0097371"(MDM2/MDM4 family protein binding)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR003185(Proteasome activator pa28, REG alpha subunit)|interpro:IPR003186(Proteasome activator pa28, REG beta subunit)|interpro:IPR009077(Proteasome activator pa28, REG alpha/beta subunit)|interpro:IPR036252|interpro:IPR036996|interpro:IPR036997|mint:P61289|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|entrezgene/locuslink:10197(identity)	-	crc64:475DA3A4F6E68E97	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:J+pCwMtq9Jhj24BeTVg7XpCHmKE559292	rogid:6EQY2Kj3Juf++m4eBDzPWMgbC2k9606	intact-crc:72CFA77ACFAA9E6D|rigid:DbAIVQbJkO3NIpxeEDw6z/iVMcw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9Y281	uniprotkb:P46680	intact:EBI-351218|uniprotkb:G3V5P4|ensembl:ENSP00000298159|ensembl:ENSP00000340635|ensembl:ENSP00000500375|ensembl:ENSP00000500532	intact:EBI-2406|uniprotkb:D6VZR5|ensemblfungi:YMR092C	psi-mi:cof2_human(display_long)|uniprotkb:CFL2(gene name)|psi-mi:CFL2(display_short)|uniprotkb:Cofilin, muscle isoform(gene name synonym)	psi-mi:aip1_yeast(display_long)|uniprotkb:AIP1(gene name)|psi-mi:AIP1(display_short)|uniprotkb:YM9582.17C(orf name)|uniprotkb:YMR092C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11542477|imex:IM-24995-2122	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_068733.1|refseq:NP_619579.1|refseq:XP_011534665.1|refseq:NP_001230574.1|dip:DIP-33178N|ensembl:ENSG00000165410(gene)|ensembl:ENST00000298159(transcript)|ensembl:ENST00000341223(transcript)|ensembl:ENST00000672163(transcript)|ensembl:ENST00000672517(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016363"(nuclear matrix)|go:"GO:0030018"(Z disc)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030043"(actin filament fragmentation)|go:"GO:0030836"(positive regulation of actin filament depolymerization)|go:"GO:0031674"(I band)|go:"GO:0045214"(sarcomere organization)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0048870"(cell motility)|go:"GO:0051014"(actin filament severing)|go:"GO:0051015"(actin filament binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002108(Actin-binding, cofilin/tropomyosin type)|interpro:IPR017904|interpro:IPR029006|mint:Q9Y281|entrezgene/locuslink:1073(identity)	refseq:NP_013810.1|sgd:S000004698|reactome:R-SCE-114608|dip:DIP-890N|ensemblfungi:YMR092C(gene)|ensemblfungi:YMR092C_mRNA(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005884"(actin filament)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030479"(actin cortical patch)|go:"GO:0030836"(positive regulation of actin filament depolymerization)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032466"(negative regulation of cytokinesis)|go:"GO:0043332"(mating projection tip)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|rcsb pdb:1PGU|rcsb pdb:1PI6|sgd:YMR092C(identity)	-	-	crc64:B8340BF68DD08257	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:HwYoUPZRkuRzqMLvuQctwNCOREA9606	rogid:TwLC/U+xqc7crYws+782F2f1rEo559292	intact-crc:031937B183605CEE|rigid:3XBdOAwfyGwKG/zP3T5emtfdSgk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P63261	uniprotkb:P46680	intact:EBI-351292|uniprotkb:P02571|uniprotkb:P14104|uniprotkb:P99022|uniprotkb:Q5U032|uniprotkb:Q96E67|uniprotkb:A8K7C2|ensembl:ENSP00000505060|ensembl:ENSP00000505193|ensembl:ENSP00000505235|ensembl:ENSP00000506126|ensembl:ENSP00000506201|ensembl:ENSP00000506253|ensembl:ENSP00000458162|ensembl:ENSP00000458435|ensembl:ENSP00000459119|ensembl:ENSP00000459124|ensembl:ENSP00000460464|ensembl:ENSP00000460660|ensembl:ENSP00000461672|ensembl:ENSP00000466346|ensembl:ENSP00000477968	intact:EBI-2406|uniprotkb:D6VZR5|ensemblfungi:YMR092C	psi-mi:actg_human(display_long)|uniprotkb:ACTG1(gene name)|psi-mi:ACTG1(display_short)|uniprotkb:ACTG(gene name synonym)|uniprotkb:Gamma-actin(gene name synonym)	psi-mi:aip1_yeast(display_long)|uniprotkb:AIP1(gene name)|psi-mi:AIP1(display_short)|uniprotkb:YM9582.17C(orf name)|uniprotkb:YMR092C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11542467|imex:IM-24995-2121	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001186883.1|refseq:NP_001605.1|ensembl:ENST00000570382(transcript)|ensembl:ENSG00000184009(gene)|ensembl:ENST00000571721(transcript)|ensembl:ENST00000573283(transcript)|ensembl:ENST00000575087(transcript)|ensembl:ENST00000575659(transcript)|ensembl:ENST00000575842(transcript)|ensembl:ENST00000575994(transcript)|ensembl:ENST00000576544(transcript)|ensembl:ENST00000615544(transcript)|ensembl:ENST00000679480(transcript)|ensembl:ENST00000679778(transcript)|ensembl:ENST00000680227(transcript)|ensembl:ENST00000680727(transcript)|ensembl:ENST00000681052(transcript)|ensembl:ENST00000681842(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0001895"(retina homeostasis)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005522"(profilin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0030016"(myofibril)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031941"(filamentous actin)|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0044305"(calyx of Held)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0051492"(regulation of stress fiber assembly)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070527"(platelet aggregation)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0072562"(blood microparticle)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0097433"(dense body)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098973"(structural constituent of postsynaptic actin cytoskeleton)|go:"GO:0120192"(tight junction assembly)|go:"GO:0120220"(basal body patch)|go:"GO:0150111"(regulation of transepithelial transport)|go:"GO:1902396"(protein localization to bicellular tight junction)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P63261|rcsb pdb:5JLH|rcsb pdb:6CXI|rcsb pdb:6CXJ|rcsb pdb:6G2T|rcsb pdb:6V62|rcsb pdb:6V63|rcsb pdb:6WK1|rcsb pdb:6WK2|reactome:R-HSA-1445148|reactome:R-HSA-190873|reactome:R-HSA-196025|reactome:R-HSA-2029482|reactome:R-HSA-3928662|reactome:R-HSA-3928665|reactome:R-HSA-418990|reactome:R-HSA-437239|reactome:R-HSA-4420097|reactome:R-HSA-445095|reactome:R-HSA-446353|reactome:R-HSA-5626467|reactome:R-HSA-5663213|reactome:R-HSA-5663220|reactome:R-HSA-5674135|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8856828|reactome:R-HSA-9013418|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9662360|reactome:R-HSA-9662361|reactome:R-HSA-9664422|entrezgene/locuslink:71(identity)	refseq:NP_013810.1|sgd:S000004698|reactome:R-SCE-114608|dip:DIP-890N|ensemblfungi:YMR092C(gene)|ensemblfungi:YMR092C_mRNA(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005884"(actin filament)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030479"(actin cortical patch)|go:"GO:0030836"(positive regulation of actin filament depolymerization)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032466"(negative regulation of cytokinesis)|go:"GO:0043332"(mating projection tip)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|rcsb pdb:1PGU|rcsb pdb:1PI6|sgd:YMR092C(identity)	-	-	crc64:B8340BF68DD08257	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:B2OOsE06lTfo90H3g8tlmUJQ7cY9606	rogid:TwLC/U+xqc7crYws+782F2f1rEo559292	intact-crc:BC7AC7F3F4F253FC|rigid:cPDgvvGA0FJRLriPJYA+vCDTtGQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P46680	uniprotkb:P60709	intact:EBI-2406|uniprotkb:D6VZR5|ensemblfungi:YMR092C	intact:EBI-353944|uniprotkb:P02570|uniprotkb:P70514|uniprotkb:P99021|uniprotkb:Q11211|uniprotkb:Q64316|uniprotkb:Q75MN2|uniprotkb:Q96B34|uniprotkb:Q96HG5|ensembl:ENSP00000494269|ensembl:ENSP00000494750|ensembl:ENSP00000495995|ensembl:ENSP00000501862|ensembl:ENSP00000502821	psi-mi:aip1_yeast(display_long)|uniprotkb:AIP1(gene name)|psi-mi:AIP1(display_short)|uniprotkb:YM9582.17C(orf name)|uniprotkb:YMR092C(locus name)	psi-mi:actb_human(display_long)|uniprotkb:ACTB(gene name)|psi-mi:ACTB(display_short)|uniprotkb:Beta-actin(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11542457|imex:IM-24995-2120	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013810.1|sgd:S000004698|reactome:R-SCE-114608|dip:DIP-890N|ensemblfungi:YMR092C(gene)|ensemblfungi:YMR092C_mRNA(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005884"(actin filament)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030479"(actin cortical patch)|go:"GO:0030836"(positive regulation of actin filament depolymerization)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032466"(negative regulation of cytokinesis)|go:"GO:0043332"(mating projection tip)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|rcsb pdb:1PGU|rcsb pdb:1PI6|sgd:YMR092C(identity)	refseq:NP_001092.1|ensembl:ENSG00000075624(gene)|ensembl:ENST00000493945(transcript)|ensembl:ENST00000642480(transcript)|ensembl:ENST00000646664(transcript)|ensembl:ENST00000674681(transcript)|ensembl:ENST00000675515(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000785"(chromatin)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0001895"(retina homeostasis)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007409"(axonogenesis)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019894"(kinesin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0022898"(regulation of transmembrane transporter activity)|go:"GO:0030027"(lamellipodium)|go:"GO:0030424"(axon)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0030957"(Tat protein binding)|go:"GO:0031982"(vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034333"(adherens junction assembly)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043044"|go:"GO:0043296"(apical junction complex)|go:"GO:0044305"(calyx of Held)|go:"GO:0045176"(apical protein localization)|go:"GO:0045202"(synapse)|go:"GO:0048156"(tau protein binding)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048870"(cell motility)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051621"(regulation of norepinephrine uptake)|go:"GO:0051623"(positive regulation of norepinephrine uptake)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070160"(tight junction)|go:"GO:0070527"(platelet aggregation)|reactome:R-HSA-4420097|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0072562"(blood microparticle)|go:"GO:0072749"(cellular response to cytochalasin B)|go:"GO:0097433"(dense body)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098973"(structural constituent of postsynaptic actin cytoskeleton)|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0150111"(regulation of transepithelial transport)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P60709|rcsb pdb:3BYH|rcsb pdb:3D2U|rcsb pdb:3J82|rcsb pdb:3LUE|rcsb pdb:6ANU|rcsb pdb:6ICT|rcsb pdb:6ICV|rcsb pdb:6LTJ|rcsb pdb:6MBJ|rcsb pdb:6MBK|rcsb pdb:6MBL|rcsb pdb:6NBW|rcsb pdb:6OX0|rcsb pdb:6OX1|rcsb pdb:6OX2|rcsb pdb:6OX3|rcsb pdb:6OX4|rcsb pdb:6OX5|rcsb pdb:6V62|rcsb pdb:6V63|rcsb pdb:6WK1|rcsb pdb:6WK2|rcsb pdb:7AS4|reactome:R-HSA-1445148|reactome:R-HSA-190873|reactome:R-HSA-196025|reactome:R-HSA-2029482|reactome:R-HSA-3214847|reactome:R-HSA-389957|reactome:R-HSA-390450|reactome:R-HSA-3928662|reactome:R-HSA-3928665|reactome:R-HSA-418990|reactome:R-HSA-437239|reactome:R-HSA-446353|reactome:R-HSA-5250924|reactome:R-HSA-5626467|reactome:R-HSA-5663213|reactome:R-HSA-5663220|reactome:R-HSA-5674135|reactome:R-HSA-5689603|reactome:R-HSA-5696394|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8856828|reactome:R-HSA-9035034|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9662360|reactome:R-HSA-9662361|reactome:R-HSA-9664422|reactome:R-HSA-983231|reactome:R-HSA-445095|dip:DIP-29686N|entrezgene/locuslink:60(identity)	-	crc64:B8340BF68DD08257	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:TwLC/U+xqc7crYws+782F2f1rEo559292	rogid:Hoge1B8Pn56kvbNTpkSLsQuHwRc9606	intact-crc:6FD7F642B6294D69|rigid:QcyuVysqGGcjywTrYed9rsrPJ28	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P46680	uniprotkb:P40123	intact:EBI-2406|uniprotkb:D6VZR5|ensemblfungi:YMR092C	intact:EBI-1051165|uniprotkb:Q6IAY2|uniprotkb:B2R5Y3|intact:EBI-11045298|uniprotkb:B7Z1C4|uniprotkb:B7Z214|ensembl:ENSP00000229922	psi-mi:aip1_yeast(display_long)|uniprotkb:AIP1(gene name)|psi-mi:AIP1(display_short)|uniprotkb:YM9582.17C(orf name)|uniprotkb:YMR092C(locus name)	psi-mi:cap2_human(display_long)|uniprotkb:CAP2(gene name)|psi-mi:CAP2(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11542448|imex:IM-24995-2119	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013810.1|sgd:S000004698|reactome:R-SCE-114608|dip:DIP-890N|ensemblfungi:YMR092C(gene)|ensemblfungi:YMR092C_mRNA(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005884"(actin filament)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030479"(actin cortical patch)|go:"GO:0030836"(positive regulation of actin filament depolymerization)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032466"(negative regulation of cytokinesis)|go:"GO:0043332"(mating projection tip)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|rcsb pdb:1PGU|rcsb pdb:1PI6|sgd:YMR092C(identity)	refseq:NP_006357.1|ensembl:ENSG00000112186(gene)|ensembl:ENST00000229922(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007165"(signal transduction)|go:"GO:0007190"(activation of adenylate cyclase activity)|go:"GO:0008179"(adenylate cyclase binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0042802"(identical protein binding)|go:"GO:0045761"(regulation of adenylate cyclase activity)|interpro:IPR001837(Adenylate cyclase-associated CAP)|interpro:IPR006599(CARP motif)|interpro:IPR013912(Adenylate cyclase-associated CAP,  C-terminal)|interpro:IPR013992(Adenylate cyclase-associated CAP, N-terminal)|interpro:IPR016098(Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal)|interpro:IPR017901|interpro:IPR018106|interpro:IPR028417|interpro:IPR028418|interpro:IPR036222|interpro:IPR036223|reactome:R-HSA-428890|go:"GO:0005886"(plasma membrane)|entrezgene/locuslink:10486(identity)	-	crc64:B8340BF68DD08257	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:TwLC/U+xqc7crYws+782F2f1rEo559292	rogid:+B9t0sirXq7xJD3kZIlab7KBR9Y9606	intact-crc:F1E8C4FE01BDC398|rigid:zfnwVDYx+4fpyXqpylfzXnZz11k	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8N6L0	uniprotkb:P46956	intact:EBI-749265|uniprotkb:Q96MC3|ensembl:ENSP00000404220	intact:EBI-13337|uniprotkb:E9P8T7|ensemblfungi:YJL117W|uniprotkb:D6VW67	psi-mi:kash5_human(display_long)|uniprotkb:KASH5(gene name)|psi-mi:KASH5(display_short)|uniprotkb:CCDC155(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 155(gene name synonym)|uniprotkb:KASH domain-containing protein 5(gene name synonym)	psi-mi:pho86_yeast(display_long)|uniprotkb:PHO86(gene name)|psi-mi:PHO86(display_short)|uniprotkb:J0744(orf name)|uniprotkb:YJL117W(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11542580|imex:IM-24995-2133	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_653289.3|ensembl:ENSG00000161609(gene)|ensembl:ENST00000447857(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034397"(telomere localization)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051225"(spindle assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0090172"(microtubule cytoskeleton organization involved in homologous chromosome segregation)|go:"GO:0090220"(chromosome localization to nuclear envelope involved in homologous chromosome segregation)|go:"GO:0090619"(meiotic spindle pole)|interpro:IPR011992(EF-Hand type)|interpro:IPR028168|interpro:IPR028170|interpro:IPR039508|mint:Q8N6L0|rcsb pdb:6R2I|rcsb pdb:6WMF|entrezgene/locuslink:147872(identity)	refseq:NP_012418.1|sgd:S000003653|interpro:IPR024297|ensemblfungi:YJL117W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006457"(protein folding)|go:"GO:0006817"(phosphate ion transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0010966"(regulation of phosphate transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0051082"(unfolded protein binding)|ensemblfungi:YJL117W(gene)|mint:P46956|dip:DIP-2769N|sgd:YJL117W(identity)	-	-	crc64:1CB19C9184BF1C48	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Wl9L7AcvDHCZuKjYLn8QgGIbZTc9606	rogid:JITWReptfMoij1Uy6y1e3Oa6dAs559292	intact-crc:54CAA4BEDC361AB9|rigid:UjXzjWJ+P5RZ9QrBKzqQGs1bp0w	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P46948	uniprotkb:Q9Y3Q8	intact:EBI-1788|uniprotkb:D6VUX7|ensemblfungi:YGR195W	intact:EBI-739485|uniprotkb:A8MWR6|ensembl:ENSP00000300181|uniprotkb:A4D2C3|uniprotkb:D6W5V9	psi-mi:rrp41_yeast(display_long)|uniprotkb:SKI6(gene name)|psi-mi:SKI6(display_short)|uniprotkb:YGR195W(locus name)|uniprotkb:G7587(orf name)|uniprotkb:ECM20(gene name synonym)|uniprotkb:Ribosomal RNA-processing protein 41(gene name synonym)|uniprotkb:Superkiller protein 6(gene name synonym)|uniprotkb:Extracellular mutant protein 20(gene name synonym)|uniprotkb:RRP41(gene name synonym)	psi-mi:t22d4_human(display_long)|uniprotkb:TSC22D4(gene name)|psi-mi:TSC22D4(display_short)|uniprotkb:TILZ2(gene name synonym)|uniprotkb:TSC22-related-inducible leucine zipper protein 2(gene name synonym)|uniprotkb:Tsc-22-like protein THG-1(gene name synonym)|uniprotkb:THG1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11542571|imex:IM-24995-2132	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003427|refseq:NP_011711.3|dip:DIP-2083N|mint:P46948|ensemblfungi:YGR195W(gene)|ensemblfungi:YGR195W_mRNA(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034473"(U1 snRNA 3'-end processing)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0034476"(U5 snRNA 3'-end processing)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071039"(nuclear polyadenylation-dependent CUT catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345|rcsb pdb:2WP8|rcsb pdb:4IFD|rcsb pdb:4OO1|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5G06|rcsb pdb:5JEA|rcsb pdb:5K36|rcsb pdb:5OKZ|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-429958|reactome:R-SCE-450385|reactome:R-SCE-450513|reactome:R-SCE-6791226|sgd:YGR195W(identity)	ensembl:ENSG00000166925(gene)|ensembl:ENST00000300181(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006970"(response to osmotic stress)|interpro:IPR000580(TSC-22 / Dip / Bun)|interpro:IPR042553|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|refseq:NP_112197.1|refseq:NP_001289972.1|entrezgene/locuslink:81628(identity)	-	crc64:C80EFFB528A43044	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:I7vEo0EUB1jZO+3v12H0LwVbgmo559292	rogid:eL12cHY76zEPOXzT1HFKPSckS8Y9606	intact-crc:5C2747E747DF6B57|rigid:ZXtHWRBKdozAbydNT2AWOJTR0OE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P46948	uniprotkb:Q9UKT9	intact:EBI-1788|uniprotkb:D6VUX7|ensemblfungi:YGR195W	intact:EBI-747204|uniprotkb:Q8WWQ9|uniprotkb:Q8WWR0|uniprotkb:Q8WWR1|uniprotkb:Q8WWR2|uniprotkb:Q8WWR3|uniprotkb:Q8N574|uniprotkb:B4DVV5|uniprotkb:Q69BL6|uniprotkb:Q69BL7|uniprotkb:Q69BL8|uniprotkb:Q69BL9|uniprotkb:Q69BM0|uniprotkb:Q69BM1|uniprotkb:Q69BM2|uniprotkb:Q69BM3|uniprotkb:Q69BM5|ensembl:ENSP00000344544	psi-mi:rrp41_yeast(display_long)|uniprotkb:SKI6(gene name)|psi-mi:SKI6(display_short)|uniprotkb:YGR195W(locus name)|uniprotkb:G7587(orf name)|uniprotkb:ECM20(gene name synonym)|uniprotkb:Ribosomal RNA-processing protein 41(gene name synonym)|uniprotkb:Superkiller protein 6(gene name synonym)|uniprotkb:Extracellular mutant protein 20(gene name synonym)|uniprotkb:RRP41(gene name synonym)	psi-mi:ikzf3_human(display_long)|uniprotkb:ZNFN1A3(gene name synonym)|uniprotkb:Ikaros family zinc finger protein 3(gene name synonym)|uniprotkb:IKZF3(gene name)|psi-mi:IKZF3(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11542562|imex:IM-24995-2131	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003427|refseq:NP_011711.3|dip:DIP-2083N|mint:P46948|ensemblfungi:YGR195W(gene)|ensemblfungi:YGR195W_mRNA(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034473"(U1 snRNA 3'-end processing)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0034476"(U5 snRNA 3'-end processing)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071039"(nuclear polyadenylation-dependent CUT catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345|rcsb pdb:2WP8|rcsb pdb:4IFD|rcsb pdb:4OO1|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5G06|rcsb pdb:5JEA|rcsb pdb:5K36|rcsb pdb:5OKZ|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-429958|reactome:R-SCE-450385|reactome:R-SCE-450513|reactome:R-SCE-6791226|sgd:YGR195W(identity)	refseq:NP_001271443.1|refseq:NP_001271444.1|refseq:NP_036613.2|refseq:NP_899051.1|refseq:NP_899052.1|refseq:NP_899053.1|refseq:NP_899054.1|refseq:NP_899055.1|refseq:NP_001271445.1|refseq:NP_001244337.1|refseq:NP_001244338.1|refseq:NP_001244339.1|refseq:NP_001244340.1|refseq:NP_001244341.1|refseq:NP_001244342.1|refseq:NP_001244343.1|ensembl:ENSG00000161405(gene)|ensembl:ENST00000346872(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007498"(mesoderm development)|go:"GO:0009617"(response to bacterium)|go:"GO:0030888"(regulation of B cell proliferation)|go:"GO:0042113"(B cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045577"(regulation of B cell differentiation)|go:"GO:0045619"(regulation of lymphocyte differentiation)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|go:"GO:0046872"(metal ion binding)|dip:DIP-56975N|entrezgene/locuslink:22806(identity)	-	crc64:C80EFFB528A43044	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:I7vEo0EUB1jZO+3v12H0LwVbgmo559292	rogid:2Kp6LefSLfK5VIiE6DmQusFIfMY9606	intact-crc:1CC42AED4419F4FD|rigid:qKDGoE2ZgJtQkWAc5Ljsw98xx9w	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96L14	uniprotkb:P46948	intact:EBI-743488	intact:EBI-1788|uniprotkb:D6VUX7|ensemblfungi:YGR195W	psi-mi:c170l_human(display_long)|uniprotkb:KIAA0470L(gene name synonym)|uniprotkb:CEP170P1(gene name)|psi-mi:CEP170P1(display_short)|uniprotkb:CEP170L(gene name synonym)|uniprotkb:CEP170 pseudogene 1(gene name synonym)	psi-mi:rrp41_yeast(display_long)|uniprotkb:SKI6(gene name)|psi-mi:SKI6(display_short)|uniprotkb:YGR195W(locus name)|uniprotkb:G7587(orf name)|uniprotkb:ECM20(gene name synonym)|uniprotkb:Ribosomal RNA-processing protein 41(gene name synonym)|uniprotkb:Superkiller protein 6(gene name synonym)|uniprotkb:Extracellular mutant protein 20(gene name synonym)|uniprotkb:RRP41(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11542553|imex:IM-24995-2130	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR026644|interpro:IPR029300|go:"GO:0042802"(identical protein binding)|entrezgene/locuslink:645455(identity)	sgd:S000003427|refseq:NP_011711.3|dip:DIP-2083N|mint:P46948|ensemblfungi:YGR195W(gene)|ensemblfungi:YGR195W_mRNA(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034473"(U1 snRNA 3'-end processing)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0034476"(U5 snRNA 3'-end processing)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071039"(nuclear polyadenylation-dependent CUT catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345|rcsb pdb:2WP8|rcsb pdb:4IFD|rcsb pdb:4OO1|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5G06|rcsb pdb:5JEA|rcsb pdb:5K36|rcsb pdb:5OKZ|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-429958|reactome:R-SCE-450385|reactome:R-SCE-450513|reactome:R-SCE-6791226|sgd:YGR195W(identity)	-	-	crc64:C80EFFB528A43044	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Z/Rium0Kwj3ZUHa4WE5PPksPXdg9606	rogid:I7vEo0EUB1jZO+3v12H0LwVbgmo559292	intact-crc:F2A0B2FCC98A3CD2|rigid:lfDGJ3ZVkgNWvR78oVXv8QekVDA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P46948	uniprotkb:Q8TAP6	intact:EBI-1788|uniprotkb:D6VUX7|ensemblfungi:YGR195W	intact:EBI-742887|ensembl:ENSP00000262127|uniprotkb:Q658N5|uniprotkb:Q9H9U7|uniprotkb:B0YJB2|uniprotkb:B4DXG5|uniprotkb:B4DZW1	psi-mi:rrp41_yeast(display_long)|uniprotkb:SKI6(gene name)|psi-mi:SKI6(display_short)|uniprotkb:YGR195W(locus name)|uniprotkb:G7587(orf name)|uniprotkb:ECM20(gene name synonym)|uniprotkb:Ribosomal RNA-processing protein 41(gene name synonym)|uniprotkb:Superkiller protein 6(gene name synonym)|uniprotkb:Extracellular mutant protein 20(gene name synonym)|uniprotkb:RRP41(gene name synonym)	psi-mi:cep76_human(display_long)|uniprotkb:CEP76(gene name)|psi-mi:CEP76(display_short)|uniprotkb:C18orf9(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11542544|imex:IM-24995-2129	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003427|refseq:NP_011711.3|dip:DIP-2083N|mint:P46948|ensemblfungi:YGR195W(gene)|ensemblfungi:YGR195W_mRNA(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034473"(U1 snRNA 3'-end processing)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0034476"(U5 snRNA 3'-end processing)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071039"(nuclear polyadenylation-dependent CUT catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345|rcsb pdb:2WP8|rcsb pdb:4IFD|rcsb pdb:4OO1|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5G06|rcsb pdb:5JEA|rcsb pdb:5K36|rcsb pdb:5OKZ|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-429958|reactome:R-SCE-450385|reactome:R-SCE-450513|reactome:R-SCE-6791226|sgd:YGR195W(identity)	refseq:NP_079175.2|ensembl:ENSG00000101624(gene)|ensembl:ENST00000262127(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0046599"(regulation of centriole replication)|interpro:IPR028926|interpro:IPR038765|mint:Q8TAP6|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_001258918.1|entrezgene/locuslink:79959(identity)	-	crc64:C80EFFB528A43044	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:I7vEo0EUB1jZO+3v12H0LwVbgmo559292	rogid:fWzb8oIU35oVWomyDrf8u5sbxUk9606	intact-crc:51517007C9F5056C|rigid:5TWeomSSqBF09jLn+neEbi3/SeA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8IYX7	uniprotkb:P46948	intact:EBI-3957636|ensembl:ENSP00000369907|intact:EBI-10174528|uniprotkb:A8K880|uniprotkb:Q5VY58	intact:EBI-1788|uniprotkb:D6VUX7|ensemblfungi:YGR195W	psi-mi:saxo1_human(display_long)|uniprotkb:SAXO1(gene name)|psi-mi:SAXO1(display_short)|uniprotkb:C9orf138(gene name synonym)|uniprotkb:FAM154A(gene name synonym)	psi-mi:rrp41_yeast(display_long)|uniprotkb:SKI6(gene name)|psi-mi:SKI6(display_short)|uniprotkb:YGR195W(locus name)|uniprotkb:G7587(orf name)|uniprotkb:ECM20(gene name synonym)|uniprotkb:Ribosomal RNA-processing protein 41(gene name synonym)|uniprotkb:Superkiller protein 6(gene name synonym)|uniprotkb:Extracellular mutant protein 20(gene name synonym)|uniprotkb:RRP41(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11542535|imex:IM-24995-2128	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000155875(gene)|ensembl:ENST00000380534(transcript)|go:"GO:0005814"(centriole)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0008017"(microtubule binding)|go:"GO:0009631"(cold acclimation)|go:"GO:0030030"(cell projection organization)|go:"GO:0031514"(motile cilium)|go:"GO:0034453"(microtubule anchoring)|go:"GO:0036064"(ciliary basal body)|go:"GO:0036126"(sperm flagellum)|go:"GO:0045724"(positive regulation of cilium assembly)|go:"GO:0050821"(protein stabilization)|go:"GO:0070417"(cellular response to cold)|interpro:IPR033336|refseq:NP_714918.2|refseq:NP_001273978.1|refseq:NP_001273979.1|entrezgene/locuslink:158297(identity)	sgd:S000003427|refseq:NP_011711.3|dip:DIP-2083N|mint:P46948|ensemblfungi:YGR195W(gene)|ensemblfungi:YGR195W_mRNA(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034473"(U1 snRNA 3'-end processing)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0034476"(U5 snRNA 3'-end processing)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071039"(nuclear polyadenylation-dependent CUT catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345|rcsb pdb:2WP8|rcsb pdb:4IFD|rcsb pdb:4OO1|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5G06|rcsb pdb:5JEA|rcsb pdb:5K36|rcsb pdb:5OKZ|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-429958|reactome:R-SCE-450385|reactome:R-SCE-450513|reactome:R-SCE-6791226|sgd:YGR195W(identity)	-	-	crc64:C80EFFB528A43044	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:34It0miSDTtv5wwJ+ERHXJzWRiQ9606	rogid:I7vEo0EUB1jZO+3v12H0LwVbgmo559292	intact-crc:F3941E014FB2B0A1|rigid:tnCrBQySz/SLCacRedV2TfSkLr0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P20807-4	uniprotkb:P46948	intact:EBI-11532021|ensembl:ENSP00000380384	intact:EBI-1788|uniprotkb:D6VUX7|ensemblfungi:YGR195W	psi-mi:p20807-4(display_long)|uniprotkb:CAPN3(gene name)|psi-mi:CAPN3(display_short)|uniprotkb:CANP3(gene name synonym)|uniprotkb:CANPL3(gene name synonym)|uniprotkb:Calcium-activated neutral proteinase 3(gene name synonym)|uniprotkb:Calpain L3(gene name synonym)|uniprotkb:Calpain p94(gene name synonym)|uniprotkb:Muscle-specific calcium-activated neutral protease 3(gene name synonym)|uniprotkb:NCL1(gene name synonym)|uniprotkb:New calpain 1(gene name synonym)	psi-mi:rrp41_yeast(display_long)|uniprotkb:SKI6(gene name)|psi-mi:SKI6(display_short)|uniprotkb:YGR195W(locus name)|uniprotkb:G7587(orf name)|uniprotkb:ECM20(gene name synonym)|uniprotkb:Ribosomal RNA-processing protein 41(gene name synonym)|uniprotkb:Superkiller protein 6(gene name synonym)|uniprotkb:Extracellular mutant protein 20(gene name synonym)|uniprotkb:RRP41(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11542526|imex:IM-24995-2127	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-5655000(isoform-parent)|uniprotkb:P20807-4(isoform-parent)|ensembl:ENSG00000092529(gene)|ensembl:ENST00000397200(transcript)|entrezgene/locuslink:825(identity)	sgd:S000003427|refseq:NP_011711.3|dip:DIP-2083N|mint:P46948|ensemblfungi:YGR195W(gene)|ensemblfungi:YGR195W_mRNA(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034473"(U1 snRNA 3'-end processing)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0034476"(U5 snRNA 3'-end processing)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071039"(nuclear polyadenylation-dependent CUT catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345|rcsb pdb:2WP8|rcsb pdb:4IFD|rcsb pdb:4OO1|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5G06|rcsb pdb:5JEA|rcsb pdb:5K36|rcsb pdb:5OKZ|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-429958|reactome:R-SCE-450385|reactome:R-SCE-450513|reactome:R-SCE-6791226|sgd:YGR195W(identity)	-	-	crc64:C80EFFB528A43044	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:6TrGg2jigHr0xYLsxBNCLjAl3J89606	rogid:I7vEo0EUB1jZO+3v12H0LwVbgmo559292	intact-crc:A6E828EA1B01EC1A|rigid:qR8dwfZsFl11ZR3gc4ETCIgmcEc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q08379	uniprotkb:P46948	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	intact:EBI-1788|uniprotkb:D6VUX7|ensemblfungi:YGR195W	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:rrp41_yeast(display_long)|uniprotkb:SKI6(gene name)|psi-mi:SKI6(display_short)|uniprotkb:YGR195W(locus name)|uniprotkb:G7587(orf name)|uniprotkb:ECM20(gene name synonym)|uniprotkb:Ribosomal RNA-processing protein 41(gene name synonym)|uniprotkb:Superkiller protein 6(gene name synonym)|uniprotkb:Extracellular mutant protein 20(gene name synonym)|uniprotkb:RRP41(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11542515|imex:IM-24995-2126	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N|entrezgene/locuslink:2801(identity)	sgd:S000003427|refseq:NP_011711.3|dip:DIP-2083N|mint:P46948|ensemblfungi:YGR195W(gene)|ensemblfungi:YGR195W_mRNA(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034473"(U1 snRNA 3'-end processing)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0034476"(U5 snRNA 3'-end processing)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071039"(nuclear polyadenylation-dependent CUT catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345|rcsb pdb:2WP8|rcsb pdb:4IFD|rcsb pdb:4OO1|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5G06|rcsb pdb:5JEA|rcsb pdb:5K36|rcsb pdb:5OKZ|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-429958|reactome:R-SCE-450385|reactome:R-SCE-450513|reactome:R-SCE-6791226|sgd:YGR195W(identity)	-	-	crc64:C80EFFB528A43044	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2017/05/26	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	rogid:I7vEo0EUB1jZO+3v12H0LwVbgmo559292	intact-crc:AA72132329642A56|rigid:aYVsQbvOuS0rfHAKF/pT/tJUV3E	false	sufficient binding region:383-1002	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P47041	intact:EBI-11524292	intact:EBI-25889|uniprotkb:D6VWC4|ensemblfungi:YJL058C	-	psi-mi:bit61_yeast(display_long)|uniprotkb:YJL058C(locus name)|uniprotkb:J1141(orf name)|uniprotkb:61 kDa binding partner of TOR2 protein(gene name synonym)|uniprotkb:BIT61(gene name)|psi-mi:BIT61(display_short)	psi-mi:trip6(display_short)|psi-mi:EBI-11524292(display_long)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11542646|imex:IM-24995-2140	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012477.1|sgd:S000003594|dip:DIP-1444N|reactome:R-SCE-1257604|reactome:R-SCE-389357|reactome:R-SCE-5218920|ensemblfungi:YJL058C(gene)|ensemblfungi:YJL058C_mRNA(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005737"(cytoplasm)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0031932"(TORC2 complex)|go:"GO:0038203"(TORC2 signaling)|go:"GO:0071944"(cell periphery)|interpro:IPR013745(HbrB-like)|reactome:R-SCE-6804757|sgd:YJL058C(identity)	entrezgene/locuslink:7205(identity)	-	crc64:99F0F96840311F4B	no-uniprot-update:	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:H+zcKwbWL90wsmvD9TfWYmEbRwM559292	rogid:S6W5lkNauGhNejln9bTVoqZjNL49606	intact-crc:031977B32BB47327|rigid:74ZznwJbqsjScwdu24D4Z64KWeg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P47041	uniprotkb:Q8N5R6	intact:EBI-25889|uniprotkb:D6VWC4|ensemblfungi:YJL058C	intact:EBI-740841|intact:EBI-953781|uniprotkb:B3KQ49|uniprotkb:A8K3U4|uniprotkb:A8MPQ6|uniprotkb:A8MV61|uniprotkb:A8MVU9|uniprotkb:Q9H5Q6|uniprotkb:Q8TAX6|intact:EBI-2320546|intact:EBI-11522976	psi-mi:bit61_yeast(display_long)|uniprotkb:YJL058C(locus name)|uniprotkb:J1141(orf name)|uniprotkb:61 kDa binding partner of TOR2 protein(gene name synonym)|uniprotkb:BIT61(gene name)|psi-mi:BIT61(display_short)	psi-mi:ccd33_human(display_long)|uniprotkb:CCDC33(gene name)|psi-mi:CCDC33(display_short)|uniprotkb:Cancer/testis antigen 61(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11542637|imex:IM-24995-2139	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012477.1|sgd:S000003594|dip:DIP-1444N|reactome:R-SCE-1257604|reactome:R-SCE-389357|reactome:R-SCE-5218920|ensemblfungi:YJL058C(gene)|ensemblfungi:YJL058C_mRNA(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005737"(cytoplasm)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0031932"(TORC2 complex)|go:"GO:0038203"(TORC2 signaling)|go:"GO:0071944"(cell periphery)|interpro:IPR013745(HbrB-like)|reactome:R-SCE-6804757|sgd:YJL058C(identity)	refseq:NP_079331.3|interpro:IPR000008(C2 calcium-dependent membrane targeting)|go:"GO:0005777"(peroxisome)|refseq:NP_001274110.1|refseq:NP_877592.2|mint:Q8N5R6|interpro:IPR035892|interpro:IPR039889|entrezgene/locuslink:80125(identity)	-	crc64:99F0F96840311F4B	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2021/11/30	rogid:H+zcKwbWL90wsmvD9TfWYmEbRwM559292	rogid:eEIn7pQyfdHWx8TeLJpYy0i/gww9606	intact-crc:36CBD3C7CAE067E6|rigid:LPWQIXNF9ahpGT/y0LCTww/kmqU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8N6L0	uniprotkb:P47013	intact:EBI-749265|uniprotkb:Q96MC3|ensembl:ENSP00000404220	intact:EBI-26081|uniprotkb:D6VW50|ensemblfungi:YJL134W	psi-mi:kash5_human(display_long)|uniprotkb:KASH5(gene name)|psi-mi:KASH5(display_short)|uniprotkb:CCDC155(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 155(gene name synonym)|uniprotkb:KASH domain-containing protein 5(gene name synonym)	psi-mi:ds1p1_yeast(display_long)|uniprotkb:YJL134W(locus name)|uniprotkb:J0671(orf name)|uniprotkb:LCB3(gene name)|psi-mi:LCB3(display_short)|uniprotkb:LBP1(gene name synonym)|uniprotkb:YSR2(gene name synonym)|uniprotkb:Long-chain base protein 3(gene name synonym)|uniprotkb:Sphingolipid resistance protein 2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11542628|imex:IM-24995-2138	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_653289.3|ensembl:ENSG00000161609(gene)|ensembl:ENST00000447857(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034397"(telomere localization)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051225"(spindle assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0090172"(microtubule cytoskeleton organization involved in homologous chromosome segregation)|go:"GO:0090220"(chromosome localization to nuclear envelope involved in homologous chromosome segregation)|go:"GO:0090619"(meiotic spindle pole)|interpro:IPR011992(EF-Hand type)|interpro:IPR028168|interpro:IPR028170|interpro:IPR039508|mint:Q8N6L0|rcsb pdb:6R2I|rcsb pdb:6WMF|entrezgene/locuslink:147872(identity)	refseq:NP_012401.1|sgd:S000003670|reactome:R-SCE-1660661|dip:DIP-5685N|ensemblfungi:YJL134W(gene)|ensemblfungi:YJL134W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0042392"(sphingosine-1-phosphate phosphatase activity)|go:"GO:0046839"(phospholipid dephosphorylation)|go:"GO:0070780"(dihydrosphingosine-1-phosphate phosphatase activity)|interpro:IPR000326(Phosphatidic acid phosphatase type 2/haloperoxidase)|interpro:IPR036938|sgd:YJL134W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Wl9L7AcvDHCZuKjYLn8QgGIbZTc9606	rogid:PY4waY+3MkYSvto7aiARAO5UHzI559292	intact-crc:D18D11A9F1B62FAD|rigid:y76M63Y2OBtRHIjH4BLDQsH9Kqc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8WV44	uniprotkb:P47009	intact:EBI-725997|uniprotkb:Q5BKT0|uniprotkb:Q7L484|uniprotkb:Q96Q10|intact:EBI-1551110|uniprotkb:Q9BSL8|uniprotkb:B3KNJ6|uniprotkb:D3DWR9|ensembl:ENSP00000320869	intact:EBI-3680883|uniprotkb:D6VW41|ensemblfungi:YJL144W	psi-mi:tri41_human(display_long)|uniprotkb:TRIM41(gene name)|psi-mi:TRIM41(display_short)|uniprotkb:RINCK(gene name synonym)|uniprotkb:Tripartite motif-containing protein 41(gene name synonym)|uniprotkb:RING finger-interacting protein with C kinase(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM41(gene name synonym)	psi-mi:yjo4_yeast(display_long)|uniprotkb:J0646(orf name)|uniprotkb:YJL144W(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11542617|imex:IM-24995-2137	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_291027.3|refseq:NP_963921.1|ensembl:ENSG00000146063(gene)|ensembl:ENST00000315073(transcript)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0042802"(identical protein binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071225"(cellular response to muramyl dipeptide)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR042828|interpro:IPR043136|mint:Q8WV44|rcsb pdb:2EGM|reactome:R-HSA-983168|entrezgene/locuslink:90933(identity)	mint:P47009|sgd:S000003680|refseq:NP_012391.1|ensemblfungi:YJL144W(gene)|ensemblfungi:YJL144W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0042631"(cellular response to water deprivation)|go:"GO:0055106"(ubiquitin-protein transferase regulator activity)|go:"GO:0120174"(stress-induced homeostatically regulated protein degradation pathway)|sgd:YJL144W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:BVqf0OHXPGsYe8F66mHzvD4XQ549606	rogid:7kshIHHxzHSMcpP1vGF+sbEHkfA559292	intact-crc:998146D7E77CAB5A|rigid:eN9UKvDnLfl7ng9xKtR6h2Aal4U	false	sufficient binding region:86-630	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P46985	uniprotkb:P63279	intact:EBI-11052|uniprotkb:E9P8Z0|ensemblfungi:YJL183W|uniprotkb:D6VW07	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	psi-mi:mnn11_yeast(display_long)|uniprotkb:MNN11(gene name)|psi-mi:MNN11(display_short)|uniprotkb:YJL183W(locus name)|uniprotkb:J0425(orf name)|uniprotkb:Mannan polymerase II complex MNN11 subunit(gene name synonym)	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11542608|imex:IM-24995-2136	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YJL183W(gene)|ensemblfungi:YJL183W_mRNA(transcript)|go:"GO:0000009"(alpha-1,6-mannosyltransferase activity)|go:"GO:0000032"(cell wall mannoprotein biosynthetic process)|go:"GO:0000136"(mannan polymerase complex)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006487"(protein N-linked glycosylation)|interpro:IPR008630(Galactosyl transferase)|interpro:IPR029044|go:"GO:0000139"(Golgi membrane)|refseq:NP_012352.2|sgd:S000003719|dip:DIP-914N|sgd:YJL183W(identity)	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N|entrezgene/locuslink:7329(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:JInEivytHOK2ZvKHg1LamaaIR70559292	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	intact-crc:375C41FB4260B2E5|rigid:BC7/cijqzTCyCeVyp5im1PNdh/w	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P46965	uniprotkb:Q8N6L0	intact:EBI-17823|uniprotkb:D6VWI6|ensemblfungi:YJR010C-A	intact:EBI-749265|uniprotkb:Q96MC3|ensembl:ENSP00000404220	psi-mi:spc1_yeast(display_long)|uniprotkb:SPC1(gene name)|psi-mi:SPC1(display_short)|uniprotkb:YJR010C-A(locus name)|uniprotkb:YJR010BW(orf name)|uniprotkb:Microsomal signal peptidase subunit 1(gene name synonym)	psi-mi:kash5_human(display_long)|uniprotkb:KASH5(gene name)|psi-mi:KASH5(display_short)|uniprotkb:CCDC155(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 155(gene name synonym)|uniprotkb:KASH domain-containing protein 5(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11542599|imex:IM-24995-2135	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012544.1|sgd:S000003770|ensemblfungi:YJR010C-A(gene)|ensemblfungi:YJR010C-A_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005787"(signal peptidase complex)|go:"GO:0006465"(signal peptide processing)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0045047"(protein targeting to ER)|interpro:IPR009542(Microsomal signal peptidase 12 kDa subunit)|interpro:IPR037713|mint:P46965|dip:DIP-2770N|sgd:YJR010C-A(identity)	refseq:NP_653289.3|ensembl:ENSG00000161609(gene)|ensembl:ENST00000447857(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034397"(telomere localization)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051225"(spindle assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0090172"(microtubule cytoskeleton organization involved in homologous chromosome segregation)|go:"GO:0090220"(chromosome localization to nuclear envelope involved in homologous chromosome segregation)|go:"GO:0090619"(meiotic spindle pole)|interpro:IPR011992(EF-Hand type)|interpro:IPR028168|interpro:IPR028170|interpro:IPR039508|mint:Q8N6L0|rcsb pdb:6R2I|rcsb pdb:6WMF|entrezgene/locuslink:147872(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:kchUi3mkadvzweVkrWO3QkbbHew559292	rogid:Wl9L7AcvDHCZuKjYLn8QgGIbZTc9606	intact-crc:D0BA9E8565734935|rigid:q6X7Z1tL2sUDclMaelgwNgDtn90	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96BA8	uniprotkb:P46956	intact:EBI-6942903|ensembl:ENSP00000481956|intact:MINT-268046|intact:MINT-8162577|uniprotkb:Q8N2D5|uniprotkb:Q96CP0	intact:EBI-13337|uniprotkb:E9P8T7|ensemblfungi:YJL117W|uniprotkb:D6VW67	psi-mi:cr3l1_human(display_long)|uniprotkb:CREB3L1(gene name)|psi-mi:CREB3L1(display_short)|uniprotkb:OASIS(gene name synonym)|uniprotkb:PSEC0238(orf name)|uniprotkb:Old astrocyte specifically-induced substance(gene name synonym)	psi-mi:pho86_yeast(display_long)|uniprotkb:PHO86(gene name)|psi-mi:PHO86(display_short)|uniprotkb:J0744(orf name)|uniprotkb:YJL117W(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11542589|imex:IM-24995-2134	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157613(gene)|ensembl:ENST00000621158(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0070278"(extracellular matrix constituent secretion)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029805|mint:Q96BA8|reactome:R-HSA-8874211|refseq:NP_443086.1|entrezgene/locuslink:90993(identity)	refseq:NP_012418.1|sgd:S000003653|interpro:IPR024297|ensemblfungi:YJL117W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006457"(protein folding)|go:"GO:0006817"(phosphate ion transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0010966"(regulation of phosphate transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0051082"(unfolded protein binding)|ensemblfungi:YJL117W(gene)|mint:P46956|dip:DIP-2769N|sgd:YJL117W(identity)	-	comment:mint|function:"Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE"	crc64:1CB19C9184BF1C48	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:sMWUFmBeBBCO+T0Y2CuB/un1lBg9606	rogid:JITWReptfMoij1Uy6y1e3Oa6dAs559292	intact-crc:3F0130FBE4C5A400|rigid:zNFUhUB559mW5v40Np8eyOmhspM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q15654	uniprotkb:P47041	intact:EBI-742327|uniprotkb:O15170|uniprotkb:O15275|uniprotkb:Q9BTB2|uniprotkb:Q9BUE5|uniprotkb:Q9BXP3|uniprotkb:Q9UNT4|uniprotkb:A4D2E7|ensembl:ENSP00000200457|uniprotkb:F2ZC07|uniprotkb:F2ZC08	intact:EBI-25889|uniprotkb:D6VWC4|ensemblfungi:YJL058C	psi-mi:trip6_human(display_long)|uniprotkb:TRIP6(gene name)|psi-mi:TRIP6(display_short)|uniprotkb:OIP1(gene name synonym)|uniprotkb:Opa-interacting protein 1(gene name synonym)|uniprotkb:Zyxin-related protein 1(gene name synonym)	psi-mi:bit61_yeast(display_long)|uniprotkb:YJL058C(locus name)|uniprotkb:J1141(orf name)|uniprotkb:61 kDa binding partner of TOR2 protein(gene name synonym)|uniprotkb:BIT61(gene name)|psi-mi:BIT61(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11542714|imex:IM-24995-2147	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003293.2|ensembl:ENSP00000200457|ensembl:ENST00000417475|ensembl:ENSP00000413817|ensembl:ENST00000437505|ensembl:ENSP00000410736|ensembl:ENST00000619988|ensembl:ENSP00000479865|ensembl:ENSG00000087077(gene)|ensembl:ENST00000200457(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003723"(RNA binding)|go:"GO:0005149"(interleukin-1 receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0019900"(kinase binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0043009"(chordate embryonic development)|go:"GO:0046872"(metal ion binding)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|interpro:IPR001781(Zinc finger, LIM-type)|mint:Q15654|rcsb pdb:1X61|rcsb pdb:2DLO|dip:DIP-34466N|entrezgene/locuslink:7205(identity)	refseq:NP_012477.1|sgd:S000003594|dip:DIP-1444N|reactome:R-SCE-1257604|reactome:R-SCE-389357|reactome:R-SCE-5218920|ensemblfungi:YJL058C(gene)|ensemblfungi:YJL058C_mRNA(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005737"(cytoplasm)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0031932"(TORC2 complex)|go:"GO:0038203"(TORC2 signaling)|go:"GO:0071944"(cell periphery)|interpro:IPR013745(HbrB-like)|reactome:R-SCE-6804757|sgd:YJL058C(identity)	-	-	crc64:99F0F96840311F4B	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:9Okf3b6sMMwX5awAx991GN9iSsQ9606	rogid:H+zcKwbWL90wsmvD9TfWYmEbRwM559292	intact-crc:935BAD9D9D02FE6D|rigid:TfpCjtS5+M2jhCdi2e0hjGITtNk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P19012	uniprotkb:P47041	intact:EBI-739566|uniprotkb:Q53XV8|uniprotkb:Q9BUG4|uniprotkb:B3KQY1|uniprotkb:B3KRA2|uniprotkb:E0CX14|ensembl:ENSP00000254043|ensembl:ENSP00000377546	intact:EBI-25889|uniprotkb:D6VWC4|ensemblfungi:YJL058C	psi-mi:k1c15_human(display_long)|uniprotkb:KRT15(gene name)|psi-mi:KRT15(display_short)|uniprotkb:KRTB(gene name synonym)|uniprotkb:Cytokeratin-15(gene name synonym)|uniprotkb:Keratin-15(gene name synonym)	psi-mi:bit61_yeast(display_long)|uniprotkb:YJL058C(locus name)|uniprotkb:J1141(orf name)|uniprotkb:61 kDa binding partner of TOR2 protein(gene name synonym)|uniprotkb:BIT61(gene name)|psi-mi:BIT61(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11542705|imex:IM-24995-2146	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002266.2|ensembl:ENSG00000171346(gene)|ensembl:ENST00000254043(transcript)|ensembl:ENST00000393976(transcript)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0008544"(epidermis development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097110"(scaffold protein binding)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR039008|mint:P19012|reactome:R-HSA-6805567|reactome:R-HSA-6809371|entrezgene/locuslink:3866(identity)	refseq:NP_012477.1|sgd:S000003594|dip:DIP-1444N|reactome:R-SCE-1257604|reactome:R-SCE-389357|reactome:R-SCE-5218920|ensemblfungi:YJL058C(gene)|ensemblfungi:YJL058C_mRNA(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005737"(cytoplasm)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0031932"(TORC2 complex)|go:"GO:0038203"(TORC2 signaling)|go:"GO:0071944"(cell periphery)|interpro:IPR013745(HbrB-like)|reactome:R-SCE-6804757|sgd:YJL058C(identity)	-	-	crc64:99F0F96840311F4B	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:WrZQBYQvrWcfrR5ojWXrXp6spPE9606	rogid:H+zcKwbWL90wsmvD9TfWYmEbRwM559292	intact-crc:EE93B0363307D2BE|rigid:6HX1d/7oa0CN5IOpc0gDYAlr24c	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P47041	uniprotkb:P14373	intact:EBI-25889|uniprotkb:D6VWC4|ensemblfungi:YJL058C	intact:EBI-719493|uniprotkb:A2BE15|uniprotkb:Q5RJA8|uniprotkb:Q5ST26|uniprotkb:Q6LA73|uniprotkb:Q6NXR9|uniprotkb:Q9BZY6|uniprotkb:Q9UJL3|ensembl:ENSP00000383555|ensembl:ENSP00000392787|ensembl:ENSP00000405229|ensembl:ENSP00000414793|ensembl:ENSP00000366404	psi-mi:bit61_yeast(display_long)|uniprotkb:YJL058C(locus name)|uniprotkb:J1141(orf name)|uniprotkb:61 kDa binding partner of TOR2 protein(gene name synonym)|uniprotkb:BIT61(gene name)|psi-mi:BIT61(display_short)	psi-mi:tri27_human(display_long)|uniprotkb:TRIM27(gene name)|psi-mi:TRIM27(display_short)|uniprotkb:RNF76(gene name synonym)|uniprotkb:RFP(gene name synonym)|uniprotkb:Ret finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 27(gene name synonym)|uniprotkb:RING finger protein 76(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM27(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11542696|imex:IM-24995-2145	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012477.1|sgd:S000003594|dip:DIP-1444N|reactome:R-SCE-1257604|reactome:R-SCE-389357|reactome:R-SCE-5218920|ensemblfungi:YJL058C(gene)|ensemblfungi:YJL058C_mRNA(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005737"(cytoplasm)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0031932"(TORC2 complex)|go:"GO:0038203"(TORC2 signaling)|go:"GO:0071944"(cell periphery)|interpro:IPR013745(HbrB-like)|reactome:R-SCE-6804757|sgd:YJL058C(identity)	refseq:NP_006501.1|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0090281"(negative regulation of calcium ion import)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR020457|interpro:IPR035791|interpro:IPR043136|mint:P14373|reactome:R-HSA-3232142|reactome:R-HSA-9635465|reactome:R-HSA-8948751|ensembl:ENSG00000204713(gene)|ensembl:ENSG00000215641(gene)|ensembl:ENSG00000229006(gene)|ensembl:ENSG00000234495(gene)|ensembl:ENSG00000237071(gene)|ensembl:ENST00000377199(transcript)|ensembl:ENST00000400720(transcript)|ensembl:ENST00000431123(transcript)|ensembl:ENST00000435528(transcript)|ensembl:ENST00000437160(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001650"(fibrillar center)|go:"GO:0002820"(negative regulation of adaptive immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|entrezgene/locuslink:5987(identity)	-	crc64:99F0F96840311F4B	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:H+zcKwbWL90wsmvD9TfWYmEbRwM559292	rogid:dsfH5OUghD8KSaTz1SFw9OYVTK49606	intact-crc:8A6A1B2B78FF4851|rigid:pFtOvJZe1d+/3DINI56Dp1R+MIE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P14136	uniprotkb:P47041	intact:EBI-744302|uniprotkb:Q53H98|uniprotkb:Q5D055|uniprotkb:Q6ZQS3|uniprotkb:Q7Z5J6|uniprotkb:Q7Z5J7|uniprotkb:Q96KS4|uniprotkb:Q96P18|uniprotkb:Q9UFD0|uniprotkb:B2RD44|uniprotkb:D3DX59|intact:EBI-3909365|uniprotkb:E9PAX3|ensembl:ENSP00000466598|uniprotkb:A7REI1	intact:EBI-25889|uniprotkb:D6VWC4|ensemblfungi:YJL058C	psi-mi:gfap_human(display_long)|uniprotkb:GFAP(gene name)|psi-mi:GFAP(display_short)	psi-mi:bit61_yeast(display_long)|uniprotkb:YJL058C(locus name)|uniprotkb:J1141(orf name)|uniprotkb:61 kDa binding partner of TOR2 protein(gene name synonym)|uniprotkb:BIT61(gene name)|psi-mi:BIT61(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11542687|imex:IM-24995-2144	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001124491.1|refseq:NP_001229305.1|refseq:NP_002046.1|ensembl:ENSG00000131095(gene)|ensembl:ENST00000588735(transcript)|go:"GO:0005178"(integrin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0009611"(response to wounding)|go:"GO:0010467"(gene expression)|go:"GO:0010625"(positive regulation of Schwann cell proliferation)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0014002"(astrocyte development)|go:"GO:0019900"(kinase binding)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0031102"(neuron projection regeneration)|go:"GO:0042802"(identical protein binding)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0044297"(cell body)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0051580"(regulation of neurotransmitter uptake)|go:"GO:0060020"(Bergmann glial cell differentiation)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0070779"(D-aspartate import across plasma membrane)|go:"GO:0097450"(astrocyte end-foot)|go:"GO:0098574"(cytoplasmic side of lysosomal membrane)|go:"GO:1904714"(regulation of chaperone-mediated autophagy)|interpro:IPR006821(Intermediate filament, DNA-binding region)|interpro:IPR018039|interpro:IPR027701|interpro:IPR039008|mint:P14136|rcsb pdb:6A9P|reactome:R-HSA-1251985|reactome:R-HSA-9613829|entrezgene/locuslink:2670(identity)	refseq:NP_012477.1|sgd:S000003594|dip:DIP-1444N|reactome:R-SCE-1257604|reactome:R-SCE-389357|reactome:R-SCE-5218920|ensemblfungi:YJL058C(gene)|ensemblfungi:YJL058C_mRNA(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005737"(cytoplasm)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0031932"(TORC2 complex)|go:"GO:0038203"(TORC2 signaling)|go:"GO:0071944"(cell periphery)|interpro:IPR013745(HbrB-like)|reactome:R-SCE-6804757|sgd:YJL058C(identity)	-	-	crc64:99F0F96840311F4B	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Pz4JW0WjMjBYILTDSX9jUmMqWhg9606	rogid:H+zcKwbWL90wsmvD9TfWYmEbRwM559292	intact-crc:BBA808895EC77345|rigid:Rk41K0v8fDB/mhKbElLL99T1QDQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P08727	uniprotkb:P47041	intact:EBI-742756|uniprotkb:Q5XG83|uniprotkb:Q6NW33|uniprotkb:Q7L5M9|uniprotkb:Q96A53|uniprotkb:Q96FV1|uniprotkb:Q9BYF9|uniprotkb:Q9P1Y4|uniprotkb:B2R874|ensembl:ENSP00000355124	intact:EBI-25889|uniprotkb:D6VWC4|ensemblfungi:YJL058C	psi-mi:k1c19_human(display_long)|uniprotkb:Cytokeratin-19(gene name synonym)|uniprotkb:Keratin-19(gene name synonym)|uniprotkb:KRT19(gene name)|psi-mi:KRT19(display_short)	psi-mi:bit61_yeast(display_long)|uniprotkb:YJL058C(locus name)|uniprotkb:J1141(orf name)|uniprotkb:61 kDa binding partner of TOR2 protein(gene name synonym)|uniprotkb:BIT61(gene name)|psi-mi:BIT61(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11542677|imex:IM-24995-2143	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002267.2|ensembl:ENSG00000171345(gene)|ensembl:ENST00000361566(transcript)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0030018"(Z disc)|go:"GO:0042383"(sarcolemma)|go:"GO:0043034"(costamere)|go:"GO:0043627"(response to estrogen)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0060706"(cell differentiation involved in embryonic placenta development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071944"(cell periphery)|go:"GO:1990357"(terminal web)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR039008|mint:P08727|reactome:R-HSA-6805567|reactome:R-HSA-6809371|dip:DIP-35655N|entrezgene/locuslink:3880(identity)	refseq:NP_012477.1|sgd:S000003594|dip:DIP-1444N|reactome:R-SCE-1257604|reactome:R-SCE-389357|reactome:R-SCE-5218920|ensemblfungi:YJL058C(gene)|ensemblfungi:YJL058C_mRNA(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005737"(cytoplasm)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0031932"(TORC2 complex)|go:"GO:0038203"(TORC2 signaling)|go:"GO:0071944"(cell periphery)|interpro:IPR013745(HbrB-like)|reactome:R-SCE-6804757|sgd:YJL058C(identity)	-	-	crc64:99F0F96840311F4B	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:fqsG2nghpcmTtI39LiYVLNYuFIA9606	rogid:H+zcKwbWL90wsmvD9TfWYmEbRwM559292	intact-crc:353FB8062E6FE9D3|rigid:aYJO7KBTuT1h4d2KpovFGq0CFeI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P47041	uniprotkb:A0A0R4J2E4	intact:EBI-25889|uniprotkb:D6VWC4|ensemblfungi:YJL058C	intact:EBI-11525602|ensembl:ENSP00000324292	psi-mi:bit61_yeast(display_long)|uniprotkb:YJL058C(locus name)|uniprotkb:J1141(orf name)|uniprotkb:61 kDa binding partner of TOR2 protein(gene name synonym)|uniprotkb:BIT61(gene name)|psi-mi:BIT61(display_short)	psi-mi:a0a0r4j2e4_human(display_long)|uniprotkb:FBF1(gene name)|psi-mi:FBF1(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11542666|imex:IM-24995-2142	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012477.1|sgd:S000003594|dip:DIP-1444N|reactome:R-SCE-1257604|reactome:R-SCE-389357|reactome:R-SCE-5218920|ensemblfungi:YJL058C(gene)|ensemblfungi:YJL058C_mRNA(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005737"(cytoplasm)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0031932"(TORC2 complex)|go:"GO:0038203"(TORC2 signaling)|go:"GO:0071944"(cell periphery)|interpro:IPR013745(HbrB-like)|reactome:R-SCE-6804757|sgd:YJL058C(identity)	ensembl:ENSG00000188878(gene)|ensembl:ENST00000319129(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0060271"(cilium assembly)|go:"GO:0090162"(establishment of epithelial cell polarity)|go:"GO:0097539"(ciliary transition fiber)|interpro:IPR033561|entrezgene/locuslink:85302(identity)	-	crc64:99F0F96840311F4B	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/03/16	rogid:H+zcKwbWL90wsmvD9TfWYmEbRwM559292	rogid:N4h8foiP1+HSYZRE7i66zhtqKlQ9606	intact-crc:9D44F3372EEB9B82|rigid:IpsLsdQqXZdgJahitU1+lffJJ5s	false	-	sufficient binding region:649-1092	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q08379	uniprotkb:P47041	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	intact:EBI-25889|uniprotkb:D6VWC4|ensemblfungi:YJL058C	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:bit61_yeast(display_long)|uniprotkb:YJL058C(locus name)|uniprotkb:J1141(orf name)|uniprotkb:61 kDa binding partner of TOR2 protein(gene name synonym)|uniprotkb:BIT61(gene name)|psi-mi:BIT61(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11542655|imex:IM-24995-2141	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N|entrezgene/locuslink:2801(identity)	refseq:NP_012477.1|sgd:S000003594|dip:DIP-1444N|reactome:R-SCE-1257604|reactome:R-SCE-389357|reactome:R-SCE-5218920|ensemblfungi:YJL058C(gene)|ensemblfungi:YJL058C_mRNA(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005737"(cytoplasm)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0031932"(TORC2 complex)|go:"GO:0038203"(TORC2 signaling)|go:"GO:0071944"(cell periphery)|interpro:IPR013745(HbrB-like)|reactome:R-SCE-6804757|sgd:YJL058C(identity)	-	-	crc64:99F0F96840311F4B	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2017/05/26	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	rogid:H+zcKwbWL90wsmvD9TfWYmEbRwM559292	intact-crc:DF127079A49C5B38|rigid:yqQ5oEjpGHrzS/87teheWUEjnyw	false	sufficient binding region:383-1002	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P47041	uniprotkb:Q8NHQ1	intact:EBI-25889|uniprotkb:D6VWC4|ensemblfungi:YJL058C	intact:EBI-739624|ensembl:ENSP00000264982|ensembl:ENSP00000419231|uniprotkb:Q96B31|uniprotkb:Q9H2C3|uniprotkb:Q9H2Z1|uniprotkb:Q9H940|uniprotkb:D3DNE9|uniprotkb:B7Z5I8|uniprotkb:B7Z7E8|uniprotkb:F5GZX8	psi-mi:bit61_yeast(display_long)|uniprotkb:YJL058C(locus name)|uniprotkb:J1141(orf name)|uniprotkb:61 kDa binding partner of TOR2 protein(gene name synonym)|uniprotkb:BIT61(gene name)|psi-mi:BIT61(display_short)	psi-mi:cep70_human(display_long)|uniprotkb:CEP70(gene name)|psi-mi:CEP70(display_short)|uniprotkb:BITE(gene name synonym)|uniprotkb:p10-binding protein(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11542773|imex:IM-24995-2153	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012477.1|sgd:S000003594|dip:DIP-1444N|reactome:R-SCE-1257604|reactome:R-SCE-389357|reactome:R-SCE-5218920|ensemblfungi:YJL058C(gene)|ensemblfungi:YJL058C_mRNA(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005737"(cytoplasm)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0031932"(TORC2 complex)|go:"GO:0038203"(TORC2 signaling)|go:"GO:0071944"(cell periphery)|interpro:IPR013745(HbrB-like)|reactome:R-SCE-6804757|sgd:YJL058C(identity)	ensembl:ENSG00000114107(gene)|ensembl:ENST00000264982(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|interpro:IPR019734|interpro:IPR037692|mint:Q8NHQ1|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|ensembl:ENST00000484888(transcript)|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_077817.2|refseq:XP_016862764.1|refseq:NP_001275893.1|refseq:NP_001275894.1|refseq:NP_001275895.1|refseq:NP_001275896.1|refseq:NP_001307527.1|refseq:NP_001307529.1|entrezgene/locuslink:80321(identity)	-	crc64:99F0F96840311F4B	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:H+zcKwbWL90wsmvD9TfWYmEbRwM559292	rogid:S4yveQWcvdVtAUX65gqrJ5Dv0Mc9606	intact-crc:1333A33C5693DD94|rigid:wRL/cjvgWWdYQhzhnRhUzoozCiY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8NA61-2	uniprotkb:P47041	intact:EBI-11524851|ensembl:ENSP00000368249|ensembl:ENSP00000480148	intact:EBI-25889|uniprotkb:D6VWC4|ensemblfungi:YJL058C	psi-mi:q8na61-2(display_long)|uniprotkb:CBY2(gene name)|psi-mi:CBY2(display_short)|uniprotkb:SPERT(gene name synonym)|uniprotkb:Spermatid-associated protein(gene name synonym)	psi-mi:bit61_yeast(display_long)|uniprotkb:YJL058C(locus name)|uniprotkb:J1141(orf name)|uniprotkb:61 kDa binding partner of TOR2 protein(gene name synonym)|uniprotkb:BIT61(gene name)|psi-mi:BIT61(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11542764|imex:IM-24995-2152	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-741724(isoform-parent)|ensembl:ENSG00000174015(gene)|ensembl:ENST00000378966(transcript)|ensembl:ENST00000610924(transcript)|uniprotkb:Q8NA61-2(isoform-parent)|entrezgene/locuslink:220082(identity)	refseq:NP_012477.1|sgd:S000003594|dip:DIP-1444N|reactome:R-SCE-1257604|reactome:R-SCE-389357|reactome:R-SCE-5218920|ensemblfungi:YJL058C(gene)|ensemblfungi:YJL058C_mRNA(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005737"(cytoplasm)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0031932"(TORC2 complex)|go:"GO:0038203"(TORC2 signaling)|go:"GO:0071944"(cell periphery)|interpro:IPR013745(HbrB-like)|reactome:R-SCE-6804757|sgd:YJL058C(identity)	-	-	crc64:99F0F96840311F4B	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:SogYcXGGMYRYzB9xKC5o0pEtsDs9606	rogid:H+zcKwbWL90wsmvD9TfWYmEbRwM559292	intact-crc:FB3DEA1E636AEAD7|rigid:sLZfmeAyOhjxlAPvkl23LA8ehaE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8IYF3-3	uniprotkb:P47041	intact:EBI-11523345|ensembl:ENSP00000363453	intact:EBI-25889|uniprotkb:D6VWC4|ensemblfungi:YJL058C	psi-mi:q8iyf3-3(display_long)|uniprotkb:TEX11(gene name)|psi-mi:TEX11(display_short)|uniprotkb:Protein ZIP4 homolog(gene name synonym)|uniprotkb:ZIP4(gene name synonym)	psi-mi:bit61_yeast(display_long)|uniprotkb:YJL058C(locus name)|uniprotkb:J1141(orf name)|uniprotkb:61 kDa binding partner of TOR2 protein(gene name synonym)|uniprotkb:BIT61(gene name)|psi-mi:BIT61(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11542753|imex:IM-24995-2151	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000120498(gene)|ensembl:ENST00000374333(transcript)|intact:EBI-742397(isoform-parent)|uniprotkb:Q8IYF3-3(isoform-parent)|entrezgene/locuslink:56159(identity)	refseq:NP_012477.1|sgd:S000003594|dip:DIP-1444N|reactome:R-SCE-1257604|reactome:R-SCE-389357|reactome:R-SCE-5218920|ensemblfungi:YJL058C(gene)|ensemblfungi:YJL058C_mRNA(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005737"(cytoplasm)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0031932"(TORC2 complex)|go:"GO:0038203"(TORC2 signaling)|go:"GO:0071944"(cell periphery)|interpro:IPR013745(HbrB-like)|reactome:R-SCE-6804757|sgd:YJL058C(identity)	-	-	crc64:99F0F96840311F4B	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:PUAMFmnm5ZV2rnJ1rhm9ZeRCixg9606	rogid:H+zcKwbWL90wsmvD9TfWYmEbRwM559292	intact-crc:98D620396214D84C|rigid:GYyPQ0bcffXr+RKuIm21GO94QJE	false	sufficient binding region:9-925	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8IYA8	uniprotkb:P47041	intact:EBI-8638439|intact:EBI-28969497|ensembl:ENSP00000296449|ensembl:ENSP00000391788|ensembl:ENSP00000407837|uniprotkb:C9JJL0|uniprotkb:Q96LP7|intact:MINT-8162095|uniprotkb:Q05DG9	intact:EBI-25889|uniprotkb:D6VWC4|ensemblfungi:YJL058C	psi-mi:iho1_human(display_long)|uniprotkb:IHO1(gene name)|psi-mi:IHO1(display_short)|uniprotkb:CCDC36(gene name synonym)|uniprotkb:Cancer/testis antigen 74(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 36(gene name synonym)	psi-mi:bit61_yeast(display_long)|uniprotkb:YJL058C(locus name)|uniprotkb:J1141(orf name)|uniprotkb:61 kDa binding partner of TOR2 protein(gene name synonym)|uniprotkb:BIT61(gene name)|psi-mi:BIT61(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11542742|imex:IM-24995-2150	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000296449|ensembl:ENST00000366429|ensembl:ENSP00000403700|ensembl:ENSP00000391788|ensembl:ENSP00000407837|ensembl:ENSG00000173421(gene)|ensembl:ENST00000296449(transcript)|ensembl:ENST00000438782(transcript)|ensembl:ENST00000452691(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0006310"(DNA recombination)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0042138"(meiotic DNA double-strand break formation)|go:"GO:0048477"(oogenesis)|go:"GO:0060629"(regulation of homologous chromosome segregation)|interpro:IPR031529|mint:Q8IYA8|refseq:XP_011531974.1|refseq:XP_011531975.1|refseq:NP_001128669.1|refseq:NP_835467.2|refseq:XP_006713187.1|entrezgene/locuslink:339834(identity)	refseq:NP_012477.1|sgd:S000003594|dip:DIP-1444N|reactome:R-SCE-1257604|reactome:R-SCE-389357|reactome:R-SCE-5218920|ensemblfungi:YJL058C(gene)|ensemblfungi:YJL058C_mRNA(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005737"(cytoplasm)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0031932"(TORC2 complex)|go:"GO:0038203"(TORC2 signaling)|go:"GO:0071944"(cell periphery)|interpro:IPR013745(HbrB-like)|reactome:R-SCE-6804757|sgd:YJL058C(identity)	-	comment:mint	crc64:99F0F96840311F4B	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:+TNQLExkhmC1NWqsE240Cx7zFVU9606	rogid:H+zcKwbWL90wsmvD9TfWYmEbRwM559292	intact-crc:D6B32B670A2155BE|rigid:7jlmiMLt3QumiVKx94sv7aao7xc	false	sufficient binding region:11-594	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P47041	uniprotkb:Q5JST6	intact:EBI-25889|uniprotkb:D6VWC4|ensemblfungi:YJL058C	intact:EBI-2349927|uniprotkb:Q9H653|uniprotkb:Q5JST8|uniprotkb:Q68DK4|uniprotkb:Q8NEI0|intact:EBI-28971886|ensembl:ENSP00000404232	psi-mi:bit61_yeast(display_long)|uniprotkb:YJL058C(locus name)|uniprotkb:J1141(orf name)|uniprotkb:61 kDa binding partner of TOR2 protein(gene name synonym)|uniprotkb:BIT61(gene name)|psi-mi:BIT61(display_short)	psi-mi:efhc2_human(display_long)|uniprotkb:EFHC2(gene name)|psi-mi:EFHC2(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11542733|imex:IM-24995-2149	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012477.1|sgd:S000003594|dip:DIP-1444N|reactome:R-SCE-1257604|reactome:R-SCE-389357|reactome:R-SCE-5218920|ensemblfungi:YJL058C(gene)|ensemblfungi:YJL058C_mRNA(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005737"(cytoplasm)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0031932"(TORC2 complex)|go:"GO:0038203"(TORC2 signaling)|go:"GO:0071944"(cell periphery)|interpro:IPR013745(HbrB-like)|reactome:R-SCE-6804757|sgd:YJL058C(identity)	ensembl:ENSP00000404232|refseq:NP_079460.2|ensembl:ENSG00000183690(gene)|ensembl:ENST00000420999(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005930"(axoneme)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0060285"(cilium-dependent cell motility)|go:"GO:0072686"(mitotic spindle)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR006602(Region of unknown function DM10)|interpro:IPR011992(EF-Hand type)|interpro:IPR040193|rcsb pdb:2Z13|rcsb pdb:2Z14|entrezgene/locuslink:80258(identity)	-	crc64:99F0F96840311F4B	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:H+zcKwbWL90wsmvD9TfWYmEbRwM559292	rogid:O1XriQSkLcYkk7H7AlanQ1FKIBY9606	intact-crc:AC3D7A45592EB0F6|rigid:04DO0Pw4mEQB80QbSnV9DtvHa8A	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P47041	uniprotkb:Q5JR59-3	intact:EBI-25889|uniprotkb:D6VWC4|ensemblfungi:YJL058C	intact:EBI-11522433|ensembl:ENSP00000370186	psi-mi:bit61_yeast(display_long)|uniprotkb:YJL058C(locus name)|uniprotkb:J1141(orf name)|uniprotkb:61 kDa binding partner of TOR2 protein(gene name synonym)|uniprotkb:BIT61(gene name)|psi-mi:BIT61(display_short)	psi-mi:q5jr59-3(display_long)|uniprotkb:MTUS2(gene name)|psi-mi:MTUS2(display_short)|uniprotkb:CAZIP(gene name synonym)|uniprotkb:Cardiac zipper protein(gene name synonym)|uniprotkb:KIAA0774(gene name synonym)|uniprotkb:Microtubule plus-end tracking protein TIP150(gene name synonym)|uniprotkb:TIP150(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11542724|imex:IM-24995-2148	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012477.1|sgd:S000003594|dip:DIP-1444N|reactome:R-SCE-1257604|reactome:R-SCE-389357|reactome:R-SCE-5218920|ensemblfungi:YJL058C(gene)|ensemblfungi:YJL058C_mRNA(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005737"(cytoplasm)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0031932"(TORC2 complex)|go:"GO:0038203"(TORC2 signaling)|go:"GO:0071944"(cell periphery)|interpro:IPR013745(HbrB-like)|reactome:R-SCE-6804757|sgd:YJL058C(identity)	ensembl:ENSG00000132938(gene)|ensembl:ENST00000380808(transcript)|intact:EBI-742948(isoform-parent)|uniprotkb:Q5JR59-3(isoform-parent)|entrezgene/locuslink:23281(identity)	-	crc64:99F0F96840311F4B	isoform-comment:No experimental confirmation available.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:H+zcKwbWL90wsmvD9TfWYmEbRwM559292	rogid:npId9tC7VoLN/jteoBiRbSYChPs9606	intact-crc:3A0F05ECDE05EE97|rigid:hyXrfFtNznuLrOumgbEL9f+b/iI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P47041	uniprotkb:Q9UKT9	intact:EBI-25889|uniprotkb:D6VWC4|ensemblfungi:YJL058C	intact:EBI-747204|uniprotkb:Q8WWQ9|uniprotkb:Q8WWR0|uniprotkb:Q8WWR1|uniprotkb:Q8WWR2|uniprotkb:Q8WWR3|uniprotkb:Q8N574|uniprotkb:B4DVV5|uniprotkb:Q69BL6|uniprotkb:Q69BL7|uniprotkb:Q69BL8|uniprotkb:Q69BL9|uniprotkb:Q69BM0|uniprotkb:Q69BM1|uniprotkb:Q69BM2|uniprotkb:Q69BM3|uniprotkb:Q69BM5|ensembl:ENSP00000344544	psi-mi:bit61_yeast(display_long)|uniprotkb:YJL058C(locus name)|uniprotkb:J1141(orf name)|uniprotkb:61 kDa binding partner of TOR2 protein(gene name synonym)|uniprotkb:BIT61(gene name)|psi-mi:BIT61(display_short)	psi-mi:ikzf3_human(display_long)|uniprotkb:ZNFN1A3(gene name synonym)|uniprotkb:Ikaros family zinc finger protein 3(gene name synonym)|uniprotkb:IKZF3(gene name)|psi-mi:IKZF3(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11542842|imex:IM-24995-2160	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012477.1|sgd:S000003594|dip:DIP-1444N|reactome:R-SCE-1257604|reactome:R-SCE-389357|reactome:R-SCE-5218920|ensemblfungi:YJL058C(gene)|ensemblfungi:YJL058C_mRNA(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005737"(cytoplasm)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0031932"(TORC2 complex)|go:"GO:0038203"(TORC2 signaling)|go:"GO:0071944"(cell periphery)|interpro:IPR013745(HbrB-like)|reactome:R-SCE-6804757|sgd:YJL058C(identity)	refseq:NP_001271443.1|refseq:NP_001271444.1|refseq:NP_036613.2|refseq:NP_899051.1|refseq:NP_899052.1|refseq:NP_899053.1|refseq:NP_899054.1|refseq:NP_899055.1|refseq:NP_001271445.1|refseq:NP_001244337.1|refseq:NP_001244338.1|refseq:NP_001244339.1|refseq:NP_001244340.1|refseq:NP_001244341.1|refseq:NP_001244342.1|refseq:NP_001244343.1|ensembl:ENSG00000161405(gene)|ensembl:ENST00000346872(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007498"(mesoderm development)|go:"GO:0009617"(response to bacterium)|go:"GO:0030888"(regulation of B cell proliferation)|go:"GO:0042113"(B cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045577"(regulation of B cell differentiation)|go:"GO:0045619"(regulation of lymphocyte differentiation)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|go:"GO:0046872"(metal ion binding)|dip:DIP-56975N|entrezgene/locuslink:22806(identity)	-	crc64:99F0F96840311F4B	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:H+zcKwbWL90wsmvD9TfWYmEbRwM559292	rogid:2Kp6LefSLfK5VIiE6DmQusFIfMY9606	intact-crc:2AA2F9FDE8F6014D|rigid:Jn6qVPw1QCEseCWRZX5P5z2dM34	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P47041	uniprotkb:Q9UJV3-2	intact:EBI-25889|uniprotkb:D6VWC4|ensemblfungi:YJL058C	intact:EBI-10172526|ensembl:ENSP00000413976	psi-mi:bit61_yeast(display_long)|uniprotkb:YJL058C(locus name)|uniprotkb:J1141(orf name)|uniprotkb:61 kDa binding partner of TOR2 protein(gene name synonym)|uniprotkb:BIT61(gene name)|psi-mi:BIT61(display_short)	psi-mi:q9ujv3-2(display_long)|uniprotkb:RING-type E3 ubiquitin transferase MID2(gene name synonym)|uniprotkb:FXY2(gene name synonym)|uniprotkb:Midin-2(gene name synonym)|uniprotkb:Midline defect 2(gene name synonym)|uniprotkb:Midline-2(gene name synonym)|uniprotkb:RING finger protein 60(gene name synonym)|uniprotkb:RNF60(gene name synonym)|uniprotkb:TRIM1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 1(gene name synonym)|uniprotkb:MID2(gene name)|psi-mi:MID2(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11542831|imex:IM-24995-2159	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012477.1|sgd:S000003594|dip:DIP-1444N|reactome:R-SCE-1257604|reactome:R-SCE-389357|reactome:R-SCE-5218920|ensemblfungi:YJL058C(gene)|ensemblfungi:YJL058C_mRNA(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005737"(cytoplasm)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0031932"(TORC2 complex)|go:"GO:0038203"(TORC2 signaling)|go:"GO:0071944"(cell periphery)|interpro:IPR013745(HbrB-like)|reactome:R-SCE-6804757|sgd:YJL058C(identity)	intact:EBI-751983(isoform-parent)|uniprotkb:Q9UJV3-2(isoform-parent)|ensembl:ENSG00000080561(gene)|ensembl:ENST00000443968(transcript)|entrezgene/locuslink:11043(identity)	-	crc64:99F0F96840311F4B	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:H+zcKwbWL90wsmvD9TfWYmEbRwM559292	rogid:/FJ+V2H7SaWon7caUWkEkmHFVxQ9606	intact-crc:3E13723BB954F2DD|rigid:hf9JTYnvR2caA0SqjlDsK8X6LhY	false	-	sufficient binding region:21-705	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UFD9	uniprotkb:P47041	intact:EBI-10182375|uniprotkb:Q9UFQ5|uniprotkb:Q8IYP7|uniprotkb:Q9BY94|intact:EBI-28984856|ensembl:ENSP00000483386	intact:EBI-25889|uniprotkb:D6VWC4|ensemblfungi:YJL058C	psi-mi:rim3a_human(display_long)|uniprotkb:RIMBP3(gene name)|psi-mi:RIMBP3(display_short)|uniprotkb:KIAA1666(gene name synonym)|uniprotkb:RIMBP3A(gene name synonym)|uniprotkb:RIMS-binding protein 3.1(gene name synonym)	psi-mi:bit61_yeast(display_long)|uniprotkb:YJL058C(locus name)|uniprotkb:J1141(orf name)|uniprotkb:61 kDa binding partner of TOR2 protein(gene name synonym)|uniprotkb:BIT61(gene name)|psi-mi:BIT61(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11542820|imex:IM-24995-2158	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_056487.1|ensembl:ENSP00000483386|ensembl:ENSG00000275793(gene)|ensembl:ENST00000619918(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007286"(spermatid development)|go:"GO:0009566"(fertilization)|go:"GO:0030156"(benzodiazepine receptor binding)|go:"GO:0045202"(synapse)|interpro:IPR001452(Src homology-3)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR035515|interpro:IPR036028|interpro:IPR036116|interpro:IPR040325|rcsb pdb:2EGE|entrezgene/locuslink:85376(identity)	refseq:NP_012477.1|sgd:S000003594|dip:DIP-1444N|reactome:R-SCE-1257604|reactome:R-SCE-389357|reactome:R-SCE-5218920|ensemblfungi:YJL058C(gene)|ensemblfungi:YJL058C_mRNA(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005737"(cytoplasm)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0031932"(TORC2 complex)|go:"GO:0038203"(TORC2 signaling)|go:"GO:0071944"(cell periphery)|interpro:IPR013745(HbrB-like)|reactome:R-SCE-6804757|sgd:YJL058C(identity)	-	-	crc64:99F0F96840311F4B	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:iw34Gee4nqAH3pqUfCgQ6Jj++AA9606	rogid:H+zcKwbWL90wsmvD9TfWYmEbRwM559292	intact-crc:3D9716668873D783|rigid:znyYkX0tH6uay7ZGWZwtp67LFKk	false	sufficient binding region:838-1639	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P47041	uniprotkb:Q9P286	intact:EBI-25889|uniprotkb:D6VWC4|ensemblfungi:YJL058C	intact:EBI-741896|ensembl:ENSP00000322957|ensembl:ENSP00000367679|ensembl:ENSP00000367686|intact:EBI-1051061|uniprotkb:A8K5T6|uniprotkb:D3DW14|uniprotkb:Q5W115|uniprotkb:Q8TB93|uniprotkb:Q9BX09|uniprotkb:Q9ULF6	psi-mi:bit61_yeast(display_long)|uniprotkb:YJL058C(locus name)|uniprotkb:J1141(orf name)|uniprotkb:61 kDa binding partner of TOR2 protein(gene name synonym)|uniprotkb:BIT61(gene name)|psi-mi:BIT61(display_short)	psi-mi:pak5_human(display_long)|uniprotkb:PAK5(gene name)|psi-mi:PAK5(display_short)|uniprotkb:KIAA1264(gene name synonym)|uniprotkb:PAK7(gene name synonym)|uniprotkb:p21-activated kinase 5(gene name synonym)|uniprotkb:p21-activated kinase 7(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11542811|imex:IM-24995-2157	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012477.1|sgd:S000003594|dip:DIP-1444N|reactome:R-SCE-1257604|reactome:R-SCE-389357|reactome:R-SCE-5218920|ensemblfungi:YJL058C(gene)|ensemblfungi:YJL058C_mRNA(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005737"(cytoplasm)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0031932"(TORC2 complex)|go:"GO:0038203"(TORC2 signaling)|go:"GO:0071944"(cell periphery)|interpro:IPR013745(HbrB-like)|reactome:R-SCE-6804757|sgd:YJL058C(identity)	ensembl:ENSG00000101349(gene)|go:"GO:0045202"(synapse)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR028754|interpro:IPR033923|interpro:IPR036936|rcsb pdb:2F57|reactome:R-HSA-428540|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013405|reactome:R-HSA-9013407|go:"GO:0043408"(regulation of MAPK cascade)|ensembl:ENST00000353224(transcript)|ensembl:ENST00000378423(transcript)|ensembl:ENST00000378429(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007165"(signal transduction)|go:"GO:0007612"(learning)|go:"GO:0007613"(memory)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016477"(cell migration)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0035556"(intracellular signal transduction)|refseq:NP_065074.1|refseq:NP_817127.1|refseq:XP_016883449.1|refseq:XP_016883450.1|refseq:XP_016883451.1|refseq:XP_016883452.1|refseq:XP_016883453.1|refseq:XP_016883454.1|entrezgene/locuslink:57144(identity)	-	crc64:99F0F96840311F4B	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2017/06/28	rogid:H+zcKwbWL90wsmvD9TfWYmEbRwM559292	rogid:xxNDwmHn4jv8toBmviGjFwBU32E9606	intact-crc:576F0ADF5239BECF|rigid:WEa7pLLKEqJ07g0CUxe3Q2BVVu0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96EY1-3	uniprotkb:P47041	intact:EBI-11526226|ensembl:ENSP00000393970	intact:EBI-25889|uniprotkb:D6VWC4|ensemblfungi:YJL058C	psi-mi:q96ey1-3(display_long)|uniprotkb:DnaJ protein Tid-1(gene name synonym)|uniprotkb:HCA57(gene name synonym)|uniprotkb:Hepatocellular carcinoma-associated antigen 57(gene name synonym)|uniprotkb:TID1(gene name synonym)|uniprotkb:Tumorous imaginal discs protein Tid56 homolog(gene name synonym)|uniprotkb:DNAJA3(gene name)|psi-mi:DNAJA3(display_short)	psi-mi:bit61_yeast(display_long)|uniprotkb:YJL058C(locus name)|uniprotkb:J1141(orf name)|uniprotkb:61 kDa binding partner of TOR2 protein(gene name synonym)|uniprotkb:BIT61(gene name)|psi-mi:BIT61(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11542800|imex:IM-24995-2156	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-356767(isoform-parent)|ensembl:ENSG00000103423(gene)|ensembl:ENST00000431375(transcript)|uniprotkb:Q96EY1-3(isoform-parent)|entrezgene/locuslink:9093(identity)	refseq:NP_012477.1|sgd:S000003594|dip:DIP-1444N|reactome:R-SCE-1257604|reactome:R-SCE-389357|reactome:R-SCE-5218920|ensemblfungi:YJL058C(gene)|ensemblfungi:YJL058C_mRNA(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005737"(cytoplasm)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0031932"(TORC2 complex)|go:"GO:0038203"(TORC2 signaling)|go:"GO:0071944"(cell periphery)|interpro:IPR013745(HbrB-like)|reactome:R-SCE-6804757|sgd:YJL058C(identity)	-	isoform-comment:"Ref.3 (BAG58345) sequence is in conflict in position: 33:Y->H."	crc64:99F0F96840311F4B	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:nMH4IaOZYO5w5bh+cdX4LoPSisc9606	rogid:H+zcKwbWL90wsmvD9TfWYmEbRwM559292	intact-crc:5C290A3B03518342|rigid:BIUcqDzPWeKiECjMQJFdyG5lduk	false	sufficient binding region:60-300	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P47041	uniprotkb:Q8WXE1-3	intact:EBI-25889|uniprotkb:D6VWC4|ensemblfungi:YJL058C	intact:EBI-11524582|ensembl:ENSP00000400930	psi-mi:bit61_yeast(display_long)|uniprotkb:YJL058C(locus name)|uniprotkb:J1141(orf name)|uniprotkb:61 kDa binding partner of TOR2 protein(gene name synonym)|uniprotkb:BIT61(gene name)|psi-mi:BIT61(display_short)	psi-mi:q8wxe1-3(display_long)|uniprotkb:ATRIP(gene name)|psi-mi:ATRIP(display_short)|uniprotkb:AGS1(gene name synonym)|uniprotkb:ATM and Rad3-related-interacting protein(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11542791|imex:IM-24995-2155	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012477.1|sgd:S000003594|dip:DIP-1444N|reactome:R-SCE-1257604|reactome:R-SCE-389357|reactome:R-SCE-5218920|ensemblfungi:YJL058C(gene)|ensemblfungi:YJL058C_mRNA(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005737"(cytoplasm)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0031932"(TORC2 complex)|go:"GO:0038203"(TORC2 signaling)|go:"GO:0071944"(cell periphery)|interpro:IPR013745(HbrB-like)|reactome:R-SCE-6804757|sgd:YJL058C(identity)	intact:EBI-747353(isoform-parent)|ensembl:ENSG00000164053(gene)|ensembl:ENST00000412052(transcript)|entrezgene/locuslink:84126(identity)	-	crc64:99F0F96840311F4B	isoform-comment:No experimental confirmation available.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:H+zcKwbWL90wsmvD9TfWYmEbRwM559292	rogid:NKCjy1jGZEySEhUOf8rJ6h9pyxY9606	intact-crc:AC4BFD6B2134A284|rigid:CTDrD9+Jv3vAlskisDMRa4OYf/k	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8WWB3	uniprotkb:P47041	intact:EBI-740680|ensembl:ENSP00000361276|ensembl:ENSP00000361278|ensembl:ENSP00000402890|uniprotkb:Q5QP03|uniprotkb:Q5QP04|uniprotkb:Q6WNP4|uniprotkb:Q6ZU87|uniprotkb:A8K927	intact:EBI-25889|uniprotkb:D6VWC4|ensemblfungi:YJL058C	psi-mi:dydc1_human(display_long)|uniprotkb:DYDC1(gene name)|psi-mi:DYDC1(display_short)|uniprotkb:DPY30D1(gene name synonym)|uniprotkb:RSD9(orf name)|uniprotkb:RSD-9(orf name)	psi-mi:bit61_yeast(display_long)|uniprotkb:YJL058C(locus name)|uniprotkb:J1141(orf name)|uniprotkb:61 kDa binding partner of TOR2 protein(gene name synonym)|uniprotkb:BIT61(gene name)|psi-mi:BIT61(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11542782|imex:IM-24995-2154	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_620167.1|ensembl:ENSG00000170788(gene)|ensembl:ENST00000372202(transcript)|ensembl:ENST00000372204(transcript)|ensembl:ENST00000421924(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0006348"|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|interpro:IPR007858(Dpy-30)|interpro:IPR037856|refseq:XP_011537636.1|refseq:XP_011537637.1|refseq:NP_001255982.1|refseq:XP_005269606.1|refseq:XP_005269607.1|entrezgene/locuslink:143241(identity)	refseq:NP_012477.1|sgd:S000003594|dip:DIP-1444N|reactome:R-SCE-1257604|reactome:R-SCE-389357|reactome:R-SCE-5218920|ensemblfungi:YJL058C(gene)|ensemblfungi:YJL058C_mRNA(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005737"(cytoplasm)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0031932"(TORC2 complex)|go:"GO:0038203"(TORC2 signaling)|go:"GO:0071944"(cell periphery)|interpro:IPR013745(HbrB-like)|reactome:R-SCE-6804757|sgd:YJL058C(identity)	-	-	crc64:99F0F96840311F4B	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:W6GUazYFXZGHGijUBpAJ5GiRuXA9606	rogid:H+zcKwbWL90wsmvD9TfWYmEbRwM559292	intact-crc:6B36ABD421C9FBAE|rigid:jN/mk7rrsZJCN6xIQ7oIzgJAC2c	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UJW9	uniprotkb:P47086	intact:EBI-748621|uniprotkb:Q96CQ2|uniprotkb:B3KQB3|ensembl:ENSP00000325414|ensembl:ENSP00000375882	intact:EBI-26299|uniprotkb:D6VWI7|uniprotkb:Q6Q5N5|ensemblfungi:YJR011C	psi-mi:srtd3_human(display_long)|uniprotkb:Replication protein-binding trans-activator(gene name synonym)|uniprotkb:SERTAD3(gene name)|psi-mi:SERTAD3(display_short)|uniprotkb:RBT1(gene name synonym)	psi-mi:yjy1_yeast(display_long)|uniprotkb:J1438(orf name)|uniprotkb:YJR83.26(orf name)|uniprotkb:YJR011C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11542905|imex:IM-24995-2167	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006723242.1|refseq:NP_037500.2|refseq:NP_976219.1|refseq:XP_005258889.1|ensembl:ENSG00000167565(gene)|ensembl:ENST00000322354(transcript)|ensembl:ENST00000392028(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR009263(SERTA)|interpro:IPR039585|entrezgene/locuslink:29946(identity)	sgd:S000003772|refseq:NP_012545.1|mint:P47086|dip:DIP-5694N|ensemblfungi:YJR011C(gene)|ensemblfungi:YJR011C_mRNA(transcript)|sgd:YJR011C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:zraVKcqHA7SNRrMV50iyPK6O7ok9606	rogid:b7YXohJEN6FMN8gYKAKboZQkxvQ559292	intact-crc:16924BB83942E92C|rigid:lPET/7vwNIdmGxP+T7v5gnf7vjE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P47086	uniprotkb:Q9NWT6	intact:EBI-26299|uniprotkb:D6VWI7|uniprotkb:Q6Q5N5|ensemblfungi:YJR011C	intact:EBI-745632|uniprotkb:Q969Q7|uniprotkb:Q9NPV5|uniprotkb:Q5W147|ensembl:ENSP00000299163|uniprotkb:D3DR69	psi-mi:yjy1_yeast(display_long)|uniprotkb:J1438(orf name)|uniprotkb:YJR83.26(orf name)|uniprotkb:YJR011C(locus name)	psi-mi:hif1n_human(display_long)|uniprotkb:Hypoxia-inducible factor asparagine hydroxylase(gene name synonym)|uniprotkb:Factor inhibiting HIF-1(gene name synonym)|uniprotkb:HIF1AN(gene name)|psi-mi:HIF1AN(display_short)|uniprotkb:FIH1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11542896|imex:IM-24995-2166	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003772|refseq:NP_012545.1|mint:P47086|dip:DIP-5694N|ensemblfungi:YJR011C(gene)|ensemblfungi:YJR011C_mRNA(transcript)|sgd:YJR011C(identity)	refseq:NP_060372.2|ensembl:ENSG00000166135(gene)|ensembl:ENST00000299163(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0036138"(peptidyl-histidine hydroxylation)|go:"GO:0036139"(peptidyl-histidine dioxygenase activity)|go:"GO:0036140"(peptidyl-asparagine 3-dioxygenase activity)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0042265"(peptidyl-asparagine hydroxylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0102113"(hypoxia-inducible factor-asparagine oxygenase activity)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027445|interpro:IPR027452|interpro:IPR041667|mint:Q9NWT6|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1H2N|rcsb pdb:1IZ3|rcsb pdb:1MZE|rcsb pdb:1MZF|rcsb pdb:1YCI|rcsb pdb:2CGN|rcsb pdb:2CGO|rcsb pdb:2ILM|rcsb pdb:2W0X|rcsb pdb:2WA3|rcsb pdb:2WA4|rcsb pdb:2XUM|rcsb pdb:2Y0I|rcsb pdb:2YC0|rcsb pdb:2YDE|rcsb pdb:3D8C|rcsb pdb:3KCX|rcsb pdb:3KCY|rcsb pdb:3OD4|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:4AI8|rcsb pdb:4B7E|rcsb pdb:4B7K|rcsb pdb:4BIO|rcsb pdb:4JAA|rcsb pdb:4NR1|rcsb pdb:4Z1V|rcsb pdb:4Z2W|rcsb pdb:5JWK|rcsb pdb:5JWL|rcsb pdb:5JWP|rcsb pdb:5OP6|rcsb pdb:6H9J|rcsb pdb:6HA6|rcsb pdb:6HC8|rcsb pdb:6HKP|rcsb pdb:6HL5|rcsb pdb:6HL6|rcsb pdb:6RUJ|reactome:R-HSA-1234174|rcsb pdb:5OP8|rcsb pdb:5OPC|dip:DIP-35527N|entrezgene/locuslink:55662(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:b7YXohJEN6FMN8gYKAKboZQkxvQ559292	rogid:lvPtfqlB1+hOcdCAwcopj/Yl+3Y9606	intact-crc:775F487447A4B0E0|rigid:nR1XPi9ZWReYQ/dZTk2ZSoxjNy4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9C0F1	uniprotkb:P47086	intact:EBI-744115|uniprotkb:A8K8W9|uniprotkb:B3KT53|uniprotkb:Q8IXZ4|uniprotkb:A8MW11|uniprotkb:D3DP42|ensembl:ENSP00000296519|ensembl:ENSP00000380009|ensembl:ENSP00000423153	intact:EBI-26299|uniprotkb:D6VWI7|uniprotkb:Q6Q5N5|ensemblfungi:YJR011C	psi-mi:cep44_human(display_long)|uniprotkb:HBV PreS1-transactivated protein 3(gene name synonym)|uniprotkb:CEP44(gene name)|psi-mi:CEP44(display_short)|uniprotkb:KIAA1712(gene name synonym)	psi-mi:yjy1_yeast(display_long)|uniprotkb:J1438(orf name)|uniprotkb:YJR83.26(orf name)|uniprotkb:YJR011C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11542887|imex:IM-24995-2165	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001035247.1|refseq:NP_001138786.1|refseq:XP_011530587.1|refseq:XP_011530588.1|refseq:XP_011530589.1|refseq:XP_016864143.1|refseq:XP_016864144.1|ensembl:ENSG00000164118(gene)|ensembl:ENST00000296519(transcript)|ensembl:ENST00000396791(transcript)|ensembl:ENST00000503780(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007099"(centriole replication)|go:"GO:0008017"(microtubule binding)|go:"GO:0010457"(centriole-centriole cohesion)|go:"GO:0030496"(midbody)|interpro:IPR029157|interpro:IPR033603|mint:Q9C0F1|entrezgene/locuslink:80817(identity)	sgd:S000003772|refseq:NP_012545.1|mint:P47086|dip:DIP-5694N|ensemblfungi:YJR011C(gene)|ensemblfungi:YJR011C_mRNA(transcript)|sgd:YJR011C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:gDTC64oDhudGdsssC7v+suIHZkA9606	rogid:b7YXohJEN6FMN8gYKAKboZQkxvQ559292	intact-crc:6DB6FE18623B2DD4|rigid:IlkQ17p7yZ9vPCBu6RWm03zPPBQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P47086	uniprotkb:Q16637-3	intact:EBI-26299|uniprotkb:D6VWI7|uniprotkb:Q6Q5N5|ensemblfungi:YJR011C	intact:EBI-395447|ensembl:ENSP00000424926|ensembl:ENSP00000486152|ensembl:ENSP00000487015|ensembl:ENSP00000487029|intact:EBI-8628183|intact:MINT-95595	psi-mi:yjy1_yeast(display_long)|uniprotkb:J1438(orf name)|uniprotkb:YJR83.26(orf name)|uniprotkb:YJR011C(locus name)	psi-mi:q16637-3(display_long)|uniprotkb:Iso7-SMN(isoform synonym)|uniprotkb:SMN1(gene name)|psi-mi:SMN1(display_short)|uniprotkb:SMN2(gene name)|psi-mi:SMN2(display_short)|uniprotkb:SMN(gene name synonym)|uniprotkb:SMNT(gene name synonym)|uniprotkb:SMNC(gene name synonym)|uniprotkb:Component of gems 1(gene name synonym)|uniprotkb:Gemin-1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11542878|imex:IM-24995-2164	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003772|refseq:NP_012545.1|mint:P47086|dip:DIP-5694N|ensemblfungi:YJR011C(gene)|ensemblfungi:YJR011C_mRNA(transcript)|sgd:YJR011C(identity)	intact:EBI-395421(smn_human)|ensembl:ENSG00000275349(gene)|ensembl:ENST00000506163(transcript)|ensembl:ENST00000626847(transcript)|ensembl:ENST00000628353(transcript)|ensembl:ENST00000628642(transcript)|ensembl:ENSG00000172062(gene)|ensembl:ENSG00000205571(gene)|ensembl:ENSG00000273772(gene)|uniprotkb:Q16637-3(isoform-parent)|entrezgene/locuslink:6607(identity)	-	-	isoform-comment:Thought to be a non-functional protein that lacks the capacity to oligomerize and thus cannot interact with Sm proteins. Primarily derived from SMN2 gene.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:b7YXohJEN6FMN8gYKAKboZQkxvQ559292	rogid:ICA63eidVxJ219M+YZJ20zNh+xU9606	intact-crc:15A99537B3C520C5|rigid:i7drGLsuBejxbIWgVhYb8wIJ0Ls	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P47086	uniprotkb:Q16637	intact:EBI-26299|uniprotkb:D6VWI7|uniprotkb:Q6Q5N5|ensemblfungi:YJR011C	intact:EBI-395421|uniprotkb:Q13119|uniprotkb:Q549U5|uniprotkb:Q96J51|ensembl:ENSP00000305857|uniprotkb:A8K0V4|ensembl:ENSP00000370083|ensembl:ENSP00000370117|ensembl:ENSP00000370119|ensembl:ENSP00000479920|ensembl:ENSP00000482966|ensembl:ENSP00000483515|ensembl:ENSP00000483819|ensembl:ENSP00000487206|ensembl:ENSP00000487421	psi-mi:yjy1_yeast(display_long)|uniprotkb:J1438(orf name)|uniprotkb:YJR83.26(orf name)|uniprotkb:YJR011C(locus name)	psi-mi:smn_human(display_long)|uniprotkb:SMN1(gene name)|psi-mi:SMN1(display_short)|uniprotkb:SMN(gene name synonym)|uniprotkb:SMNT(gene name synonym)|uniprotkb:SMN2(gene name)|psi-mi:SMN2(display_short)|uniprotkb:SMNC(gene name synonym)|uniprotkb:Component of gems 1(gene name synonym)|uniprotkb:Gemin-1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11542869|imex:IM-24995-2163	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003772|refseq:NP_012545.1|mint:P47086|dip:DIP-5694N|ensemblfungi:YJR011C(gene)|ensemblfungi:YJR011C_mRNA(transcript)|sgd:YJR011C(identity)	refseq:NP_000335.1|refseq:NP_059107.1|refseq:NP_075012.1|refseq:NP_075013.1|refseq:NP_075014.1|refseq:NP_075015.1|ensembl:ENSG00000172062(gene)|ensembl:ENSG00000205571(gene)|ensembl:ENSG00000273772(gene)|ensembl:ENSG00000275349(gene)|ensembl:ENSG00000277773(gene)|ensembl:ENST00000351205(transcript)|ensembl:ENST00000380707(transcript)|ensembl:ENST00000380741(transcript)|ensembl:ENST00000380743(transcript)|ensembl:ENST00000614610(transcript)|ensembl:ENST00000618251(transcript)|ensembl:ENST00000618661(transcript)|ensembl:ENST00000622739(transcript)|ensembl:ENST00000627341(transcript)|ensembl:ENST00000629122(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0007399"(nervous system development)|go:"GO:0015030"(Cajal body)|go:"GO:0016604"(nuclear body)|go:"GO:0030018"(Z disc)|go:"GO:0030424"(axon)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043204"(perikaryon)|go:"GO:0097504"(Gemini of coiled bodies)|interpro:IPR002999(Tudor)|interpro:IPR010304(Survival motor neuron)|mint:Q16637|rcsb pdb:1G5V|rcsb pdb:1MHN|rcsb pdb:2LEH|rcsb pdb:4A4E|rcsb pdb:4A4G|rcsb pdb:4GLI|rcsb pdb:4QQ6|rcsb pdb:5XJL|go:"GO:0034719"(SMN-Sm protein complex)|rcsb pdb:5XJQ|rcsb pdb:5XJR|rcsb pdb:5XJS|rcsb pdb:5XJT|rcsb pdb:5XJU|reactome:R-HSA-191859|go:"GO:0032797"(SMN complex)|refseq:NP_001284644.1|ensembl:ENSP00000305857|ensembl:ENSP00000370083|ensembl:ENSP00000370117|ensembl:ENST00000380742|ensembl:ENSP00000370118|ensembl:ENSP00000370119|ensembl:ENST00000503079|ensembl:ENSP00000428128|ensembl:ENST00000506163|ensembl:ENSP00000424926|ensembl:ENST00000611442|ensembl:ENSP00000483768|ensembl:ENST00000614240|ensembl:ENSP00000479279|ensembl:ENSP00000479920|ensembl:ENST00000614773|ensembl:ENSP00000481427|ensembl:ENSP00000483515|ensembl:ENSP00000483819|ensembl:ENST00000622158|ensembl:ENSP00000480906|ensembl:ENSP00000482966|ensembl:ENST00000624634|ensembl:ENSP00000485595|ensembl:ENST00000626847|ensembl:ENSP00000486152|ensembl:ENSP00000487421|ensembl:ENST00000628353|ensembl:ENSP00000487029|ensembl:ENST00000628642|ensembl:ENSP00000487015|ensembl:ENSP00000487206|refseq:XP_016865275.1|dip:DIP-31309N|entrezgene/locuslink:6607(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:b7YXohJEN6FMN8gYKAKboZQkxvQ559292	rogid:QGivm7E8suciCWXO4l0zCUzCl2g9606	intact-crc:2B91A65130EFCA6C|rigid:ZQ6NMREfPqDMd+YBfYo0Pj7l2A0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P47086	uniprotkb:P78356-2	intact:EBI-26299|uniprotkb:D6VWI7|uniprotkb:Q6Q5N5|ensemblfungi:YJR011C	intact:EBI-11532361	psi-mi:yjy1_yeast(display_long)|uniprotkb:J1438(orf name)|uniprotkb:YJR83.26(orf name)|uniprotkb:YJR011C(locus name)	psi-mi:p78356-2(display_long)|uniprotkb:PIP4K2B(gene name)|psi-mi:PIP4K2B(display_short)|uniprotkb:1-phosphatidylinositol 5-phosphate 4-kinase 2-beta(gene name synonym)|uniprotkb:Diphosphoinositide kinase 2-beta(gene name synonym)|uniprotkb:PIP5K2B(gene name synonym)|uniprotkb:Phosphatidylinositol 5-phosphate 4-kinase type II beta(gene name synonym)|uniprotkb:"PtdIns(5)P-4-kinase isoform 2-beta"(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11542860|imex:IM-24995-2162	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003772|refseq:NP_012545.1|mint:P47086|dip:DIP-5694N|ensemblfungi:YJR011C(gene)|ensemblfungi:YJR011C_mRNA(transcript)|sgd:YJR011C(identity)	intact:EBI-947090(isoform-parent)|uniprotkb:P78356-2(isoform-parent)|entrezgene/locuslink:8396(identity)	-	-	isoform-comment:No experimental confirmation available.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:b7YXohJEN6FMN8gYKAKboZQkxvQ559292	rogid:vM046yHfiRTiHTWlLYpaqEegf0o9606	intact-crc:580EAF61C240246E|rigid:u9P+H3Bj4VVQyFi4wgifyu5XH0g	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9Y2D8	uniprotkb:P47041	intact:EBI-2212028|uniprotkb:B4DFE3|uniprotkb:J3KR02|uniprotkb:A8K8W0|uniprotkb:D3DT13|uniprotkb:Q6P2P8|uniprotkb:Q6ULS1|uniprotkb:Q7L168|uniprotkb:Q9UIX0|intact:EBI-10964529|ensembl:ENSP00000340279	intact:EBI-25889|uniprotkb:D6VWC4|ensemblfungi:YJL058C	psi-mi:adip_human(display_long)|uniprotkb:SSX2IP(gene name)|psi-mi:SSX2IP(display_short)|uniprotkb:KIAA0923(gene name synonym)|uniprotkb:Afadin DIL domain-interacting protein(gene name synonym)|uniprotkb:SSX2-interacting protein(gene name synonym)	psi-mi:bit61_yeast(display_long)|uniprotkb:YJL058C(locus name)|uniprotkb:J1141(orf name)|uniprotkb:61 kDa binding partner of TOR2 protein(gene name synonym)|uniprotkb:BIT61(gene name)|psi-mi:BIT61(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11542851|imex:IM-24995-2161	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011538912.1|refseq:NP_001159765.1|refseq:NP_001159766.1|refseq:NP_001159767.1|refseq:NP_001159889.1|refseq:NP_054740.3|refseq:XP_005270484.1|refseq:XP_005270485.1|refseq:XP_006710394.1|refseq:XP_016855723.1|ensembl:ENSG00000117155(gene)|ensembl:ENST00000342203(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005912"(adherens junction)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031252"(cell leading edge)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0035735"(intraciliary transport involved in cilium assembly)|go:"GO:0036064"(ciliary basal body)|go:"GO:0060271"(cilium assembly)|go:"GO:2000145"(regulation of cell motility)|interpro:IPR021622|mint:Q9Y2D8|entrezgene/locuslink:117178(identity)	refseq:NP_012477.1|sgd:S000003594|dip:DIP-1444N|reactome:R-SCE-1257604|reactome:R-SCE-389357|reactome:R-SCE-5218920|ensemblfungi:YJL058C(gene)|ensemblfungi:YJL058C_mRNA(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005737"(cytoplasm)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0031932"(TORC2 complex)|go:"GO:0038203"(TORC2 signaling)|go:"GO:0071944"(cell periphery)|interpro:IPR013745(HbrB-like)|reactome:R-SCE-6804757|sgd:YJL058C(identity)	-	-	crc64:99F0F96840311F4B	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:E0VeMRF9SrpQKSJFP01XEbMjeF89606	rogid:H+zcKwbWL90wsmvD9TfWYmEbRwM559292	intact-crc:10A56AA2600723F8|rigid:GsJ5roI+fl2JX8Dy+oaZhNpR7Fc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P47130	uniprotkb:Q8NHQ1	intact:EBI-763|uniprotkb:D6VWQ3|ensemblfungi:YJR084W	intact:EBI-739624|ensembl:ENSP00000264982|ensembl:ENSP00000419231|uniprotkb:Q96B31|uniprotkb:Q9H2C3|uniprotkb:Q9H2Z1|uniprotkb:Q9H940|uniprotkb:D3DNE9|uniprotkb:B7Z5I8|uniprotkb:B7Z7E8|uniprotkb:F5GZX8	psi-mi:csn12_yeast(display_long)|uniprotkb:J1860(orf name)|uniprotkb:YJR084W(locus name)|uniprotkb:CSN12(gene name)|psi-mi:CSN12(display_short)	psi-mi:cep70_human(display_long)|uniprotkb:CEP70(gene name)|psi-mi:CEP70(display_short)|uniprotkb:BITE(gene name synonym)|uniprotkb:p10-binding protein(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11542981|imex:IM-24995-2175	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012617.1|sgd:S000003844|dip:DIP-6710N|mint:P47130|ensemblfungi:YJR084W(gene)|ensemblfungi:YJR084W_mRNA(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000754"(adaptation of signaling pathway by response to pheromone involved in conjugation with cellular fusion)|go:"GO:0000973"(posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0070390"(transcription export complex 2)|go:"GO:0071033"|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR036388|sgd:YJR084W(identity)	ensembl:ENSG00000114107(gene)|ensembl:ENST00000264982(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|interpro:IPR019734|interpro:IPR037692|mint:Q8NHQ1|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|ensembl:ENST00000484888(transcript)|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_077817.2|refseq:XP_016862764.1|refseq:NP_001275893.1|refseq:NP_001275894.1|refseq:NP_001275895.1|refseq:NP_001275896.1|refseq:NP_001307527.1|refseq:NP_001307529.1|entrezgene/locuslink:80321(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:3mwOzmQkVCLzVvabW1WAjChHkg8559292	rogid:S4yveQWcvdVtAUX65gqrJ5Dv0Mc9606	intact-crc:31550CBE45A68689|rigid:vZhLFDSYHDxeoMiZ7ixn8lWni20	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96BA8	uniprotkb:P47124	intact:EBI-6942903|ensembl:ENSP00000481956|intact:MINT-268046|intact:MINT-8162577|uniprotkb:Q8N2D5|uniprotkb:Q96CP0	intact:EBI-8430|uniprotkb:E9P8X6|uniprotkb:D6VWP5|ensemblfungi:YJR075W	psi-mi:cr3l1_human(display_long)|uniprotkb:CREB3L1(gene name)|psi-mi:CREB3L1(display_short)|uniprotkb:OASIS(gene name synonym)|uniprotkb:PSEC0238(orf name)|uniprotkb:Old astrocyte specifically-induced substance(gene name synonym)	psi-mi:hoc1_yeast(display_long)|uniprotkb:HOC1(gene name)|psi-mi:HOC1(display_short)|uniprotkb:YJR075W(locus name)|uniprotkb:J1830(orf name)|uniprotkb:Mannan polymerase II complex HOC1 subunit(gene name synonym)|uniprotkb:M-Pol II subunit Hoc1p(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11542972|imex:IM-24995-2174	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157613(gene)|ensembl:ENST00000621158(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0070278"(extracellular matrix constituent secretion)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029805|mint:Q96BA8|reactome:R-HSA-8874211|refseq:NP_443086.1|entrezgene/locuslink:90993(identity)	sgd:S000003836|refseq:NP_012609.3|dip:DIP-918N|ensemblfungi:YJR075W(gene)|ensemblfungi:YJR075W_mRNA(transcript)|go:"GO:0000009"(alpha-1,6-mannosyltransferase activity)|go:"GO:0000032"(cell wall mannoprotein biosynthetic process)|go:"GO:0000136"(mannan polymerase complex)|go:"GO:0006080"(substituted mannan metabolic process)|go:"GO:0006491"(N-glycan processing)|interpro:IPR007577(Glycosyltransferase sugar-binding region containing DXD motif)|interpro:IPR029044|interpro:IPR039367|sgd:YJR075W(identity)	-	comment:mint|function:"Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE"	crc64:8BF77385510DE6B0	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:sMWUFmBeBBCO+T0Y2CuB/un1lBg9606	rogid:wfRzXnEiSgEJNFaUo37t6GRAYmY559292	intact-crc:9BC3E6E99982C857|rigid:6zFeAftRsIp5f5CsGelMlyM8KK0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P19012	uniprotkb:P47121	intact:EBI-739566|uniprotkb:Q53XV8|uniprotkb:Q9BUG4|uniprotkb:B3KQY1|uniprotkb:B3KRA2|uniprotkb:E0CX14|ensembl:ENSP00000254043|ensembl:ENSP00000377546	intact:EBI-11532457|ensemblfungi:YJR071W	psi-mi:k1c15_human(display_long)|uniprotkb:KRT15(gene name)|psi-mi:KRT15(display_short)|uniprotkb:KRTB(gene name synonym)|uniprotkb:Cytokeratin-15(gene name synonym)|uniprotkb:Keratin-15(gene name synonym)	psi-mi:yj41_yeast(display_long)|uniprotkb:J1818(orf name)|uniprotkb:YJR071W(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11542963|imex:IM-24995-2173	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002266.2|ensembl:ENSG00000171346(gene)|ensembl:ENST00000254043(transcript)|ensembl:ENST00000393976(transcript)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0008544"(epidermis development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097110"(scaffold protein binding)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR039008|mint:P19012|reactome:R-HSA-6805567|reactome:R-HSA-6809371|entrezgene/locuslink:3866(identity)	sgd:S000003832|ensemblfungi:YJR071W(gene)|ensemblfungi:YJR071W_mRNA(transcript)|sgd:YJR071W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/03/16	rogid:WrZQBYQvrWcfrR5ojWXrXp6spPE9606	rogid:5IM71Y0Z5uWfytzg3rXeNU+zCIs559292	intact-crc:3C3EE7B06975EDDD|rigid:N7wAs75Cz60FYATyk61zyKc9+i0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P14136	uniprotkb:P47121	intact:EBI-744302|uniprotkb:Q53H98|uniprotkb:Q5D055|uniprotkb:Q6ZQS3|uniprotkb:Q7Z5J6|uniprotkb:Q7Z5J7|uniprotkb:Q96KS4|uniprotkb:Q96P18|uniprotkb:Q9UFD0|uniprotkb:B2RD44|uniprotkb:D3DX59|intact:EBI-3909365|uniprotkb:E9PAX3|ensembl:ENSP00000466598|uniprotkb:A7REI1	intact:EBI-11532457|ensemblfungi:YJR071W	psi-mi:gfap_human(display_long)|uniprotkb:GFAP(gene name)|psi-mi:GFAP(display_short)	psi-mi:yj41_yeast(display_long)|uniprotkb:J1818(orf name)|uniprotkb:YJR071W(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11542954|imex:IM-24995-2172	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001124491.1|refseq:NP_001229305.1|refseq:NP_002046.1|ensembl:ENSG00000131095(gene)|ensembl:ENST00000588735(transcript)|go:"GO:0005178"(integrin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0009611"(response to wounding)|go:"GO:0010467"(gene expression)|go:"GO:0010625"(positive regulation of Schwann cell proliferation)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0014002"(astrocyte development)|go:"GO:0019900"(kinase binding)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0031102"(neuron projection regeneration)|go:"GO:0042802"(identical protein binding)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0044297"(cell body)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0051580"(regulation of neurotransmitter uptake)|go:"GO:0060020"(Bergmann glial cell differentiation)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0070779"(D-aspartate import across plasma membrane)|go:"GO:0097450"(astrocyte end-foot)|go:"GO:0098574"(cytoplasmic side of lysosomal membrane)|go:"GO:1904714"(regulation of chaperone-mediated autophagy)|interpro:IPR006821(Intermediate filament, DNA-binding region)|interpro:IPR018039|interpro:IPR027701|interpro:IPR039008|mint:P14136|rcsb pdb:6A9P|reactome:R-HSA-1251985|reactome:R-HSA-9613829|entrezgene/locuslink:2670(identity)	sgd:S000003832|ensemblfungi:YJR071W(gene)|ensemblfungi:YJR071W_mRNA(transcript)|sgd:YJR071W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/03/16	rogid:Pz4JW0WjMjBYILTDSX9jUmMqWhg9606	rogid:5IM71Y0Z5uWfytzg3rXeNU+zCIs559292	intact-crc:5726D33D2CA57AC4|rigid:sThOr4vPEYaMHtC3NM5RUYom1j8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96BA8	uniprotkb:P47111	intact:EBI-6942903|ensembl:ENSP00000481956|intact:MINT-268046|intact:MINT-8162577|uniprotkb:Q8N2D5|uniprotkb:Q96CP0	intact:EBI-25497|uniprotkb:D6VWL5|ensemblfungi:YJR044C	psi-mi:cr3l1_human(display_long)|uniprotkb:CREB3L1(gene name)|psi-mi:CREB3L1(display_short)|uniprotkb:OASIS(gene name synonym)|uniprotkb:PSEC0238(orf name)|uniprotkb:Old astrocyte specifically-induced substance(gene name synonym)	psi-mi:vps55_yeast(display_long)|uniprotkb:J1637(orf name)|uniprotkb:YJR044C(locus name)|uniprotkb:VPS55(gene name)|psi-mi:VPS55(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11542945|imex:IM-24995-2171	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157613(gene)|ensembl:ENST00000621158(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0070278"(extracellular matrix constituent secretion)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029805|mint:Q96BA8|reactome:R-HSA-8874211|refseq:NP_443086.1|entrezgene/locuslink:90993(identity)	sgd:S000003805|refseq:NP_012578.3|dip:DIP-7667N|mint:P47111|ensemblfungi:YJR044C(gene)|ensemblfungi:YJR044C_mRNA(transcript)|go:"GO:0005768"(endosome)|go:"GO:0005770"(late endosome)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0034424"(Vps55/Vps68 complex)|go:"GO:2000009"(negative regulation of protein localization to cell surface)|interpro:IPR007262(Vacuolar protein sorting 55)|sgd:YJR044C(identity)	-	comment:mint|function:"Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE"	crc64:1F207E62F093FC6D	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:sMWUFmBeBBCO+T0Y2CuB/un1lBg9606	rogid:J23lc6VW+GZsH/Tu+ukXF5QauPg559292	intact-crc:FD3253BE96DC4C03|rigid:pDAsg3dJ2BzWP56eURgXagnzwS8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P47107	uniprotkb:Q9HCM9-2	intact:EBI-2344909|uniprotkb:D6VWL0|ensemblfungi:YJR039W	intact:EBI-11523450|ensembl:ENSP00000365847|ensembl:ENSP00000373095|ensembl:ENSP00000373097|ensembl:ENSP00000379797|ensembl:ENSP00000379800|ensembl:ENSP00000383486|ensembl:ENSP00000387445|ensembl:ENSP00000389198|ensembl:ENSP00000389852|ensembl:ENSP00000392130|ensembl:ENSP00000394353|ensembl:ENSP00000396986|ensembl:ENSP00000398956|ensembl:ENSP00000401071|ensembl:ENSP00000401184|ensembl:ENSP00000404340|ensembl:ENSP00000404904|ensembl:ENSP00000411582|ensembl:ENSP00000412743|ensembl:ENSP00000414525|ensembl:ENSP00000415259	psi-mi:yj09_yeast(display_long)|uniprotkb:J1614(orf name)|uniprotkb:YJR039W(locus name)	psi-mi:q9hcm9-2(display_long)|uniprotkb:TRIM39(gene name)|psi-mi:TRIM39(display_short)|uniprotkb:RING finger protein 23(gene name synonym)|uniprotkb:RNF23(gene name synonym)|uniprotkb:TFP(gene name synonym)|uniprotkb:Testis-abundant finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 39(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM39(gene name synonym)|uniprotkb:TIM39beta(isoform synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11542935|imex:IM-24995-2170	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003800|refseq:NP_012573.1|ensemblfungi:YJR039W(gene)|ensemblfungi:YJR039W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|sgd:YJR039W(identity)	intact:EBI-739510(isoform-parent)|ensembl:ENSG00000204599(gene)|ensembl:ENSG00000206495(gene)|ensembl:ENSG00000224994(gene)|ensembl:ENSG00000226437(gene)|ensembl:ENSG00000229929(gene)|ensembl:ENSG00000230308(gene)|ensembl:ENSG00000232839(gene)|ensembl:ENST00000376659(transcript)|ensembl:ENST00000383601(transcript)|ensembl:ENST00000383603(transcript)|ensembl:ENST00000396548(transcript)|ensembl:ENST00000396551(transcript)|ensembl:ENST00000400644(transcript)|ensembl:ENST00000414015(transcript)|ensembl:ENST00000419790(transcript)|ensembl:ENST00000430502(transcript)|ensembl:ENST00000431272(transcript)|ensembl:ENST00000433900(transcript)|ensembl:ENST00000438076(transcript)|ensembl:ENST00000438859(transcript)|ensembl:ENST00000440117(transcript)|ensembl:ENST00000443109(transcript)|ensembl:ENST00000446397(transcript)|ensembl:ENST00000449318(transcript)|ensembl:ENST00000450778(transcript)|ensembl:ENST00000451132(transcript)|ensembl:ENST00000452705(transcript)|ensembl:ENST00000458607(transcript)|uniprotkb:Q9HCM9-2(isoform-parent)|entrezgene/locuslink:56658(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:79jOtKfgrrdJYmThBSRaCtpPF5A559292	rogid:UfSn2+IVRxtGomVeDGdZpL7mz5I9606	intact-crc:50800EB59A99D47C|rigid:0feV6Q6LdnFm13FzOqFPEOK8Dyg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O43765	uniprotkb:P47094	intact:EBI-347996|ensembl:ENSP00000221566|ensembl:ENSP00000503397|ensembl:ENSP00000504495|uniprotkb:Q9BTZ9|intact:EBI-1045243|uniprotkb:Q6FIA9|uniprotkb:D6W610	intact:EBI-26323|ensemblfungi:YJR023C	psi-mi:sgta_human(display_long)|uniprotkb:SGTA(gene name)|psi-mi:SGTA(display_short)|uniprotkb:SGT(gene name synonym)|uniprotkb:Alpha-SGT(gene name synonym)|uniprotkb:Vpu-binding protein(gene name synonym)|uniprotkb:SGT1(gene name synonym)	psi-mi:yjz3_yeast(display_long)|uniprotkb:J1470(orf name)|uniprotkb:YJR83.19(orf name)|uniprotkb:YJR023C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11542926|imex:IM-24995-2169	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:4CPG|rcsb pdb:4GOD|rcsb pdb:4GOE|rcsb pdb:4GOF|reactome:R-HSA-9609523|rcsb pdb:2VYI|ensembl:ENSG00000104969(gene)|ensembl:ENST00000221566(transcript)|ensembl:ENST00000676943(transcript)|ensembl:ENST00000677149(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072380"(TRC complex)|go:"GO:0098850"(extrinsic component of synaptic vesicle membrane)|go:"GO:1903070"(negative regulation of ER-associated ubiquitin-dependent protein catabolic process)|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)|go:"GO:1903646"(positive regulation of chaperone-mediated protein folding)|go:"GO:1904288"(BAT3 complex binding)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR032374|mint:O43765|refseq:XP_011526480.1|refseq:NP_003012.1|entrezgene/locuslink:6449(identity)	sgd:S000003784|dip:DIP-2641N|ensemblfungi:YJR023C(gene)|ensemblfungi:YJR023C_mRNA(transcript)|go:"GO:0016021"(integral component of membrane)|sgd:YJR023C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:r/Cyj4UJk/cS8QdrbjhTZMPCigI9606	rogid:lOcQ5QyAEpXz/uROltQZ2quCgzI559292	intact-crc:4202F12FA9DA915F|rigid:xIqeVpaNWZvv+ifhaApFY44L+H4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96BA8	uniprotkb:P47088	intact:EBI-6942903|ensembl:ENSP00000481956|intact:MINT-268046|intact:MINT-8162577|uniprotkb:Q8N2D5|uniprotkb:Q96CP0	intact:EBI-26307|uniprotkb:D6VWI9|uniprotkb:E9P8R4|ensemblfungi:YJR013W	psi-mi:cr3l1_human(display_long)|uniprotkb:CREB3L1(gene name)|psi-mi:CREB3L1(display_short)|uniprotkb:OASIS(gene name synonym)|uniprotkb:PSEC0238(orf name)|uniprotkb:Old astrocyte specifically-induced substance(gene name synonym)	psi-mi:gpi14_yeast(display_long)|uniprotkb:GPI mannosyltransferase I(gene name synonym)|uniprotkb:Glycosylphosphatidylinositol-anchor biosynthesis protein 14(gene name synonym)|uniprotkb:YJR013W(locus name)|uniprotkb:J1444(orf name)|uniprotkb:YJR83.11(orf name)|uniprotkb:GPI14(gene name)|psi-mi:GPI14(display_short)|uniprotkb:PMH1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11542914|imex:IM-24995-2168	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157613(gene)|ensembl:ENST00000621158(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0070278"(extracellular matrix constituent secretion)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029805|mint:Q96BA8|reactome:R-HSA-8874211|refseq:NP_443086.1|entrezgene/locuslink:90993(identity)	refseq:NP_012547.2|sgd:S000003774|interpro:IPR007704(Mannosyltransferase, DXD)|ensemblfungi:YJR013W(gene)|ensemblfungi:YJR013W_mRNA(transcript)|go:"GO:0004376"(glycolipid mannosyltransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006506"(GPI anchor biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0051751"(alpha-1,4-mannosyltransferase activity)|go:"GO:1990529"(glycosylphosphatidylinositol-mannosyltransferase I complex)|sgd:YJR013W(identity)	-	comment:mint|function:"Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE"	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:sMWUFmBeBBCO+T0Y2CuB/un1lBg9606	rogid:I8WI1aDIsik8nbDq7V/vf4UY9oQ559292	intact-crc:30712E5023A724E9|rigid:t6bn5S4A1t6XXfXKIRvCY7ja3UE	false	-	sufficient binding region:99-403	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96H20	uniprotkb:P47142	intact:EBI-747719|uniprotkb:Q8IXY3|uniprotkb:Q9UN50|ensembl:ENSP00000421380	intact:EBI-25595|uniprotkb:D6VWS1|ensemblfungi:YJR102C	psi-mi:snf8_human(display_long)|uniprotkb:ELL-associated protein of 30 kDa(gene name synonym)|uniprotkb:SNF8(gene name)|psi-mi:SNF8(display_short)|uniprotkb:EAP30(gene name synonym)|uniprotkb:ESCRT-II complex subunit VPS22(gene name synonym)	psi-mi:vps25_yeast(display_long)|uniprotkb:YJR102C(locus name)|uniprotkb:J1957(orf name)|uniprotkb:VPS25(gene name)|psi-mi:VPS25(display_short)|uniprotkb:VPT25(gene name synonym)|uniprotkb:ESCRT-II complex subunit VPS25(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11543017|imex:IM-24995-2179	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009172.2|refseq:NP_001304121.1|refseq:NP_001304122.1|refseq:NP_001304123.1|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010008"(endosome membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0016247"(channel regulator activity)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043328"(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055037"(recycling endosome)|go:"GO:0061635"(regulation of protein complex stability)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071985"(multivesicular body sorting pathway)|go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:1903772"(regulation of viral budding via host ESCRT complex)|interpro:IPR016689(ESCRT-2 complex, Snf8)|interpro:IPR036388|interpro:IPR036390|interpro:IPR040608|mint:Q96H20|rcsb pdb:2ZME|rcsb pdb:3CUQ|reactome:R-HSA-917729|reactome:R-HSA-9610379|ensembl:ENSG00000159210(gene)|ensembl:ENST00000502492(transcript)|go:"GO:0000814"(ESCRT II complex)|entrezgene/locuslink:11267(identity)	refseq:NP_012636.1|sgd:S000003863|mint:P47142|dip:DIP-4446N|ensemblfungi:YJR102C(gene)|ensemblfungi:YJR102C_mRNA(transcript)|go:"GO:0000433"(carbon catabolite repression of transcription from RNA polymerase II promoter by glucose)|go:"GO:0000814"(ESCRT II complex)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043328"(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:1904669"(ATP export)|interpro:IPR008570(ESCRT-II complex, vps25 subunit)|interpro:IPR014041(ESCRT-II complex, vps25 subunit, N-terminal winged helix)|interpro:IPR036388|interpro:IPR036390|rcsb pdb:1U5T|rcsb pdb:1W7P|rcsb pdb:1XB4|reactome:R-SCE-917729|sgd:YJR102C(identity)	-	-	crc64:6A4545A8BC772CA2	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:FyjlBpOt9okBFV8Z+g8YLUeyCm49606	rogid:LlNZVpWKYsWsgu0FcP2sL10lYHc559292	intact-crc:15D896E64DC0C76A|rigid:FYnf8xbP9QsNSNXgRnwRbzuWSOE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P47141	uniprotkb:O00444	intact:EBI-25588|uniprotkb:D6VWS0|ensemblfungi:YJR101W	intact:EBI-746202|uniprotkb:Q8IYF0|uniprotkb:Q96Q95|uniprotkb:B2RAL0|uniprotkb:B7Z837|uniprotkb:B7Z8G7|uniprotkb:Q9UD84|uniprotkb:Q9UDE2|ensembl:ENSP00000270861	psi-mi:rt26_yeast(display_long)|uniprotkb:RSM26(gene name)|psi-mi:RSM26(display_short)|uniprotkb:Mitochondrial small ribosomal subunit protein mS42(gene name synonym)|uniprotkb:J1952(orf name)|uniprotkb:YJR101W(locus name)	psi-mi:plk4_human(display_long)|uniprotkb:Polo-like kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase Sak(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 18(gene name synonym)|uniprotkb:PLK4(gene name)|psi-mi:PLK4(display_short)|uniprotkb:SAK(gene name synonym)|uniprotkb:STK18(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11543008|imex:IM-24995-2178	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012635.1|sgd:S000003862|mint:P47141|dip:DIP-6695N|ensemblfungi:YJR101W(gene)|ensemblfungi:YJR101W_mRNA(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0004784"(superoxide dismutase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0032543"(mitochondrial translation)|go:"GO:0046872"(metal ion binding)|interpro:IPR019832|interpro:IPR036314|interpro:IPR036324|rcsb pdb:5MRC|rcsb pdb:5MRE|rcsb pdb:5MRF|sgd:YJR101W(identity)	refseq:NP_001177728.1|refseq:NP_001177730.1|refseq:NP_055079.3|dip:DIP-34467N|rcsb pdb:5LHZ|rcsb pdb:6N45|rcsb pdb:6N46|rcsb pdb:6W38|rcsb pdb:6W3I|rcsb pdb:6W3J|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|rcsb pdb:5LHY|reactome:R-HSA-5620912|reactome:R-HSA-8854518|ensembl:ENSG00000142731(gene)|ensembl:ENST00000270861(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0001741"(XY body)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007099"(centriole replication)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0046601"(positive regulation of centriole replication)|go:"GO:0060271"(cilium assembly)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0098535"(de novo centriole assembly involved in multi-ciliated epithelial cell differentiation)|go:"GO:0098536"(deuterosome)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033696|interpro:IPR033698|interpro:IPR033699|interpro:IPR033700|mint:O00444|rcsb pdb:2N19|rcsb pdb:3COK|rcsb pdb:4JXF|rcsb pdb:4N7V|rcsb pdb:4N7Z|rcsb pdb:4N9J|rcsb pdb:4YUR|rcsb pdb:4YYP|entrezgene/locuslink:10733(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:SlIhesyBGcjVv9vDlv43gnSLZ2o559292	rogid:xqjVEnoGXDk/+2AzLRAkyPK80OI9606	intact-crc:AEB20F41A8FCD211|rigid:YSl4RqDpH160BRgvgBss6G3F8xE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P47133	uniprotkb:Q8N6Y0	intact:EBI-25568|uniprotkb:D6VWQ6|uniprotkb:Q66R61|ensemblfungi:YJR088C	intact:EBI-739895|uniprotkb:Q8NBX7|uniprotkb:Q96KH3|uniprotkb:Q9BYI8|uniprotkb:A8K7L6|uniprotkb:B2RCR9|ensembl:ENSP00000252597	psi-mi:emc2_yeast(display_long)|uniprotkb:EMC2(gene name)|psi-mi:EMC2(display_short)|uniprotkb:J1875(orf name)|uniprotkb:YJR088C(locus name)	psi-mi:usbp1_human(display_long)|uniprotkb:USHBP1(gene name)|psi-mi:USHBP1(display_short)|uniprotkb:MCC-2(gene name synonym)|uniprotkb:AIE-75-binding protein(gene name synonym)|uniprotkb:AIEBP(gene name synonym)|uniprotkb:MCC2(gene name synonym)|uniprotkb:Mutated in colon cancer protein 2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11542999|imex:IM-24995-2177	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012621.1|sgd:S000003848|dip:DIP-7609N|ensemblfungi:YJR088C(gene)|ensemblfungi:YJR088C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0072546"(EMC complex)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR039856|rcsb pdb:6WB9|rcsb pdb:7KRA|rcsb pdb:7KTX|sgd:YJR088C(identity)	refseq:NP_001284632.1|refseq:NP_114147.2|refseq:NP_001308346.1|ensembl:ENSG00000130307(gene)|ensembl:ENST00000252597(transcript)|go:"GO:0030165"(PDZ domain binding)|interpro:IPR019536|interpro:IPR040171|entrezgene/locuslink:83878(identity)	-	crc64:157A03E75FB9E72A	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:p1r7k3QtfCRO93w9iBzh6wYGL9Q559292	rogid:vY1qx73Ju/z7WDu6k1kd10ZDVRo9606	intact-crc:AA1D167B3C4DDCB3|rigid:FYmRLOyXsbEWBakVmoQuJEvha18	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P47133	uniprotkb:P50222	intact:EBI-25568|uniprotkb:D6VWQ6|uniprotkb:Q66R61|ensemblfungi:YJR088C	intact:EBI-748397|uniprotkb:O75263|ensembl:ENSP00000262041|uniprotkb:Q9UPL6|uniprotkb:B2R8I7|intact:EBI-10172134|intact:EBI-11522964|intact:EBI-11750003|intact:EBI-12702266|uniprotkb:A4D127	psi-mi:emc2_yeast(display_long)|uniprotkb:EMC2(gene name)|psi-mi:EMC2(display_short)|uniprotkb:J1875(orf name)|uniprotkb:YJR088C(locus name)	psi-mi:meox2_human(display_long)|uniprotkb:Mesenchyme homeobox 2(gene name synonym)|uniprotkb:Growth arrest-specific homeobox(gene name synonym)|uniprotkb:MEOX2(gene name)|psi-mi:MEOX2(display_short)|uniprotkb:GAX(gene name synonym)|uniprotkb:MOX2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11542990|imex:IM-24995-2176	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012621.1|sgd:S000003848|dip:DIP-7609N|ensemblfungi:YJR088C(gene)|ensemblfungi:YJR088C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0072546"(EMC complex)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR039856|rcsb pdb:6WB9|rcsb pdb:7KRA|rcsb pdb:7KTX|sgd:YJR088C(identity)	ensembl:ENSG00000106511(gene)|ensembl:ENST00000262041(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0001757"(somite specification)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007275"(multicellular organism development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008015"(blood circulation)|go:"GO:0016607"(nuclear speck)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060173"(limb development)|go:"GO:0061053"(somite development)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR042634|refseq:NP_005915.2|entrezgene/locuslink:4223(identity)	-	crc64:157A03E75FB9E72A	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2017/05/26	rogid:p1r7k3QtfCRO93w9iBzh6wYGL9Q559292	rogid:fMv0ruKikzQ3MC0PBvJ3pOAjW+U9606	intact-crc:1FEB534AD1E9F765|rigid:Nl+LiBV9j9ECxZnmhoSaGE9xlXc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P19012	uniprotkb:P48232	intact:EBI-739566|uniprotkb:Q53XV8|uniprotkb:Q9BUG4|uniprotkb:B3KQY1|uniprotkb:B3KRA2|uniprotkb:E0CX14|ensembl:ENSP00000254043|ensembl:ENSP00000377546	intact:EBI-28775|uniprotkb:D6W193|ensemblfungi:YNL086W	psi-mi:k1c15_human(display_long)|uniprotkb:KRT15(gene name)|psi-mi:KRT15(display_short)|uniprotkb:KRTB(gene name synonym)|uniprotkb:Cytokeratin-15(gene name synonym)|uniprotkb:Keratin-15(gene name synonym)	psi-mi:snapn_yeast(display_long)|uniprotkb:YNL086W(locus name)|uniprotkb:N2254(orf name)|uniprotkb:SNN1(gene name)|psi-mi:SNN1(display_short)|uniprotkb:SNAPIN-like protein 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11543084|imex:IM-24995-2186	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002266.2|ensembl:ENSG00000171346(gene)|ensembl:ENST00000254043(transcript)|ensembl:ENST00000393976(transcript)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0008544"(epidermis development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097110"(scaffold protein binding)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR039008|mint:P19012|reactome:R-HSA-6805567|reactome:R-HSA-6809371|entrezgene/locuslink:3866(identity)	refseq:NP_014313.1|sgd:S000005030|dip:DIP-1188N|mint:P48232|ensemblfungi:YNL086W(gene)|ensemblfungi:YNL086W_mRNA(transcript)|go:"GO:0005768"(endosome)|go:"GO:0007032"(endosome organization)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0032880"(regulation of protein localization)|sgd:YNL086W(identity)	-	-	crc64:33200D2F0F729DA1	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:WrZQBYQvrWcfrR5ojWXrXp6spPE9606	rogid:XCPaHuGC9oKD/3W0gY5ZY8jKtFs559292	intact-crc:5EEA0D8195A8913D|rigid:hL9Sjv5M1RtaCp4N61Zl1BEcb5g	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P08727	uniprotkb:P48232	intact:EBI-742756|uniprotkb:Q5XG83|uniprotkb:Q6NW33|uniprotkb:Q7L5M9|uniprotkb:Q96A53|uniprotkb:Q96FV1|uniprotkb:Q9BYF9|uniprotkb:Q9P1Y4|uniprotkb:B2R874|ensembl:ENSP00000355124	intact:EBI-28775|uniprotkb:D6W193|ensemblfungi:YNL086W	psi-mi:k1c19_human(display_long)|uniprotkb:Cytokeratin-19(gene name synonym)|uniprotkb:Keratin-19(gene name synonym)|uniprotkb:KRT19(gene name)|psi-mi:KRT19(display_short)	psi-mi:snapn_yeast(display_long)|uniprotkb:YNL086W(locus name)|uniprotkb:N2254(orf name)|uniprotkb:SNN1(gene name)|psi-mi:SNN1(display_short)|uniprotkb:SNAPIN-like protein 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11543074|imex:IM-24995-2185	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002267.2|ensembl:ENSG00000171345(gene)|ensembl:ENST00000361566(transcript)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0030018"(Z disc)|go:"GO:0042383"(sarcolemma)|go:"GO:0043034"(costamere)|go:"GO:0043627"(response to estrogen)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0060706"(cell differentiation involved in embryonic placenta development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071944"(cell periphery)|go:"GO:1990357"(terminal web)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR039008|mint:P08727|reactome:R-HSA-6805567|reactome:R-HSA-6809371|dip:DIP-35655N|entrezgene/locuslink:3880(identity)	refseq:NP_014313.1|sgd:S000005030|dip:DIP-1188N|mint:P48232|ensemblfungi:YNL086W(gene)|ensemblfungi:YNL086W_mRNA(transcript)|go:"GO:0005768"(endosome)|go:"GO:0007032"(endosome organization)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0032880"(regulation of protein localization)|sgd:YNL086W(identity)	-	-	crc64:33200D2F0F729DA1	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:fqsG2nghpcmTtI39LiYVLNYuFIA9606	rogid:XCPaHuGC9oKD/3W0gY5ZY8jKtFs559292	intact-crc:47CAF1ADBADC8998|rigid:CwltGDU4oRqebkTElyclVSZmLGU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96BA8	uniprotkb:P47190	intact:EBI-6942903|ensembl:ENSP00000481956|intact:MINT-268046|intact:MINT-8162577|uniprotkb:Q8N2D5|uniprotkb:Q96CP0	intact:EBI-13579|uniprotkb:D6W319|ensemblfungi:YOR321W	psi-mi:cr3l1_human(display_long)|uniprotkb:CREB3L1(gene name)|psi-mi:CREB3L1(display_short)|uniprotkb:OASIS(gene name synonym)|uniprotkb:PSEC0238(orf name)|uniprotkb:Old astrocyte specifically-induced substance(gene name synonym)	psi-mi:pmt3_yeast(display_long)|uniprotkb:PMT3(gene name)|psi-mi:PMT3(display_short)|uniprotkb:O6148(orf name)|uniprotkb:YOR321W(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11543065|imex:IM-24995-2184	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157613(gene)|ensembl:ENST00000621158(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0070278"(extracellular matrix constituent secretion)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029805|mint:Q96BA8|reactome:R-HSA-8874211|refseq:NP_443086.1|entrezgene/locuslink:90993(identity)	refseq:NP_014966.1|sgd:S000005848|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:0097582"(dolichyl-phosphate-mannose-protein mannosyltransferase Pmt1p-Pmt2p dimer complex)|go:"GO:0097583"(dolichyl-phosphate-mannose-protein mannosyltransferase Pmt1p-Pmt3p dimer complex)|go:"GO:0097585"(dolichyl-phosphate-mannose-protein mannosyltransferase Pmt5p-Pmt3p dimer complex)|interpro:IPR003342(Glycosyl transferase, family 39)|interpro:IPR016093(MIR motif)|interpro:IPR027005|interpro:IPR032421|ensemblfungi:YOR321W(gene)|ensemblfungi:YOR321W_mRNA(transcript)|go:"GO:0004169"(dolichyl-phosphate-mannose-protein mannosyltransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006493"(protein O-linked glycosylation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035269"(protein O-linked mannosylation)|interpro:IPR036300|rcsb pdb:6ZQQ|dip:DIP-5158N|sgd:YOR321W(identity)	-	comment:mint|function:"Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE"	crc64:F076473B41EB6CBA	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:sMWUFmBeBBCO+T0Y2CuB/un1lBg9606	rogid:JsPUkzaK8sNWifvo5m9Ixhly2P8559292	intact-crc:B86E063F22A00126|rigid:xKfN74/ZVuRBhxSOHz5/z8hDN4A	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:A0A024R4Q5	uniprotkb:P47167	intact:EBI-11527449	intact:EBI-25691|uniprotkb:D6VWV3|ensemblfungi:YJR135C	psi-mi:a0a024r4q5_human(display_long)|uniprotkb:hCG_20946(orf name)|uniprotkb:TFPT(gene name)|psi-mi:TFPT(display_short)	psi-mi:cenpk_yeast(display_long)|uniprotkb:YJR135C(locus name)|uniprotkb:J2122(orf name)|uniprotkb:MCM22(gene name)|psi-mi:MCM22(display_short)|uniprotkb:Minichromosome maintenance protein 22(gene name synonym)|uniprotkb:CENP-K homolog(gene name synonym)|uniprotkb:Constitutive centromere-associated network protein MCM22(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11543054|imex:IM-24995-2183	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_037474.1|interpro:IPR033555|go:"GO:0005654"(nucleoplasm)|go:"GO:0006915"(apoptotic process)|entrezgene/locuslink:29844(identity)	sgd:S000003896|refseq:NP_012669.1|mint:P47167|dip:DIP-1431N|ensemblfungi:YJR135C(gene)|ensemblfungi:YJR135C_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0007059"(chromosome segregation)|go:"GO:0034087"(establishment of mitotic sister chromatid cohesion)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|rcsb pdb:6OUA|rcsb pdb:6QLD|rcsb pdb:6QLE|rcsb pdb:6WUC|rcsb pdb:6YPC|rcsb pdb:7L7Q|sgd:YJR135C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:juI/3gZemjc0hnXDJ9J+bIQ9pBw9606	rogid:LcYkK++8vfcxUaACTUgOFftDVyc559292	intact-crc:06120B2393C2D4E2|rigid:ZTXIMsSGw1x74kumZO63mW+N3Co	false	sufficient binding region:10-253	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P47162	uniprotkb:Q15038	intact:EBI-11532550|uniprotkb:A0A1S0T089|ensemblfungi:YJR128W	intact:EBI-724310|ensembl:ENSP00000394699|uniprotkb:E9PB45|uniprotkb:A8K254|uniprotkb:B4DDT5|uniprotkb:C9JA96|uniprotkb:C9JP84|uniprotkb:B4E1G3|uniprotkb:F8VU62	psi-mi:yj98_yeast(display_long)|uniprotkb:J2059(orf name)|uniprotkb:YJR128W(locus name)	psi-mi:dazp2_human(display_long)|uniprotkb:Deleted in azoospermia-associated protein 2(gene name synonym)|uniprotkb:DAZAP2(gene name)|psi-mi:DAZAP2(display_short)|uniprotkb:KIAA0058(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11543045|imex:IM-24995-2182	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003889|ensemblfungi:YJR128W(gene)|ensemblfungi:YJR128W_mRNA(transcript)|sgd:YJR128W(identity)	ensembl:ENSG00000183283(gene)|ensembl:ENST00000412716(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0016607"(nuclear speck)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0050699"(WW domain binding)|interpro:IPR022730|mint:Q15038|refseq:NP_001129736.1|refseq:NP_055579.1|ensembl:ENSP00000394699|ensembl:ENST00000425012|ensembl:ENSP00000408251|ensembl:ENST00000439799|ensembl:ENSP00000398804|ensembl:ENST00000449723|ensembl:ENSP00000412812|ensembl:ENST00000549555|ensembl:ENSP00000448051|ensembl:ENST00000549732|ensembl:ENSP00000446554|refseq:NP_001129741.1|refseq:NP_001129739.1|refseq:NP_001129740.1|refseq:NP_001129738.1|entrezgene/locuslink:9802(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/03/16	rogid:utEI06SlO/HvqiPnUtJUHtxxOBo559292	rogid:ASRqCZBG4q1U/y95PUSMKsgfm/g9606	intact-crc:3AC3C3544CF6CB07|rigid:wfMFpeoVlRmYhu/ezZM1vkzm8ek	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96BA8	uniprotkb:P47155	intact:EBI-6942903|ensembl:ENSP00000481956|intact:MINT-268046|intact:MINT-8162577|uniprotkb:Q8N2D5|uniprotkb:Q96CP0	intact:EBI-2051644|uniprotkb:D6VWT7|ensemblfungi:YJR118C	psi-mi:cr3l1_human(display_long)|uniprotkb:CREB3L1(gene name)|psi-mi:CREB3L1(display_short)|uniprotkb:OASIS(gene name synonym)|uniprotkb:PSEC0238(orf name)|uniprotkb:Old astrocyte specifically-induced substance(gene name synonym)	psi-mi:ilm1_yeast(display_long)|uniprotkb:Increased loss of mitochondrial DNA protein 1(gene name synonym)|uniprotkb:J2033(orf name)|uniprotkb:ILM1(gene name)|psi-mi:ILM1(display_short)|uniprotkb:YJR118C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11543035|imex:IM-24995-2181	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157613(gene)|ensembl:ENST00000621158(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0070278"(extracellular matrix constituent secretion)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029805|mint:Q96BA8|reactome:R-HSA-8874211|refseq:NP_443086.1|entrezgene/locuslink:90993(identity)	sgd:S000003879|interpro:IPR018815|refseq:NP_012652.3|mint:P47155|ensemblfungi:YJR118C(gene)|ensemblfungi:YJR118C_mRNA(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|sgd:YJR118C(identity)	-	comment:mint|function:"Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE"	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:sMWUFmBeBBCO+T0Y2CuB/un1lBg9606	rogid:BrQhbXGvUjNG6Bt5c0J7T8qzMeI559292	intact-crc:630D0179E1BA2AAE|rigid:lCg7wDQ2zuSIP1rO0i23xqrT9Zg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96H20-2	uniprotkb:P47142	intact:EBI-11121416|ensembl:ENSP00000290330	intact:EBI-25595|uniprotkb:D6VWS1|ensemblfungi:YJR102C	psi-mi:q96h20-2(display_long)|uniprotkb:SNF8(gene name)|psi-mi:SNF8(display_short)|uniprotkb:EAP30(gene name synonym)|uniprotkb:ELL-associated protein of 30 kDa(gene name synonym)|uniprotkb:ESCRT-II complex subunit VPS22(gene name synonym)	psi-mi:vps25_yeast(display_long)|uniprotkb:YJR102C(locus name)|uniprotkb:J1957(orf name)|uniprotkb:VPS25(gene name)|psi-mi:VPS25(display_short)|uniprotkb:VPT25(gene name synonym)|uniprotkb:ESCRT-II complex subunit VPS25(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11543026|imex:IM-24995-2180	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-747719(isoform-parent)|ensembl:ENSG00000159210(gene)|ensembl:ENST00000290330(transcript)|entrezgene/locuslink:11267(identity)	refseq:NP_012636.1|sgd:S000003863|mint:P47142|dip:DIP-4446N|ensemblfungi:YJR102C(gene)|ensemblfungi:YJR102C_mRNA(transcript)|go:"GO:0000433"(carbon catabolite repression of transcription from RNA polymerase II promoter by glucose)|go:"GO:0000814"(ESCRT II complex)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043328"(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:1904669"(ATP export)|interpro:IPR008570(ESCRT-II complex, vps25 subunit)|interpro:IPR014041(ESCRT-II complex, vps25 subunit, N-terminal winged helix)|interpro:IPR036388|interpro:IPR036390|rcsb pdb:1U5T|rcsb pdb:1W7P|rcsb pdb:1XB4|reactome:R-SCE-917729|sgd:YJR102C(identity)	-	isoform-comment:No experimental confirmation available.	crc64:6A4545A8BC772CA2	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Q8Kde7wzzgiTELEbfVpV36PVV5E9606	rogid:LlNZVpWKYsWsgu0FcP2sL10lYHc559292	intact-crc:E3D7002B28A310DA|rigid:B0FGWfS0RZ18UHY60iRrpmjLYVQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48232	uniprotkb:Q9BUW7	intact:EBI-28775|uniprotkb:D6W193|ensemblfungi:YNL086W	intact:EBI-752084|uniprotkb:Q9Y3F7|uniprotkb:Q5SYV8|ensembl:ENSP00000362085	psi-mi:snapn_yeast(display_long)|uniprotkb:YNL086W(locus name)|uniprotkb:N2254(orf name)|uniprotkb:SNN1(gene name)|psi-mi:SNN1(display_short)|uniprotkb:SNAPIN-like protein 1(gene name synonym)	psi-mi:bbln_human(display_long)|uniprotkb:BBLN(gene name)|psi-mi:BBLN(display_short)|uniprotkb:C9orf16(gene name synonym)|uniprotkb:UPF0184 protein C9orf16(gene name synonym)|uniprotkb:EST00098(orf name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11543147|imex:IM-24995-2193	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014313.1|sgd:S000005030|dip:DIP-1188N|mint:P48232|ensemblfungi:YNL086W(gene)|ensemblfungi:YNL086W_mRNA(transcript)|go:"GO:0005768"(endosome)|go:"GO:0007032"(endosome organization)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0032880"(regulation of protein localization)|sgd:YNL086W(identity)	refseq:NP_077017.1|dip:DIP-29481N|ensembl:ENSG00000171159(gene)|ensembl:ENST00000372994(transcript)|interpro:IPR005374(Protein of unknown function UPF0184)|entrezgene/locuslink:79095(identity)	-	crc64:33200D2F0F729DA1	crc64:EBE1D0AFAAD6DABB	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:XCPaHuGC9oKD/3W0gY5ZY8jKtFs559292	rogid:O4VcHghk63gMrjyh5XKmkZovFZ49606	intact-crc:E605346E5008FB58|rigid:iljLLz95tUWEiho68kbnmxPDoTE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96L14	uniprotkb:P48232	intact:EBI-743488	intact:EBI-28775|uniprotkb:D6W193|ensemblfungi:YNL086W	psi-mi:c170l_human(display_long)|uniprotkb:KIAA0470L(gene name synonym)|uniprotkb:CEP170P1(gene name)|psi-mi:CEP170P1(display_short)|uniprotkb:CEP170L(gene name synonym)|uniprotkb:CEP170 pseudogene 1(gene name synonym)	psi-mi:snapn_yeast(display_long)|uniprotkb:YNL086W(locus name)|uniprotkb:N2254(orf name)|uniprotkb:SNN1(gene name)|psi-mi:SNN1(display_short)|uniprotkb:SNAPIN-like protein 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11543138|imex:IM-24995-2192	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR026644|interpro:IPR029300|go:"GO:0042802"(identical protein binding)|entrezgene/locuslink:645455(identity)	refseq:NP_014313.1|sgd:S000005030|dip:DIP-1188N|mint:P48232|ensemblfungi:YNL086W(gene)|ensemblfungi:YNL086W_mRNA(transcript)|go:"GO:0005768"(endosome)|go:"GO:0007032"(endosome organization)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0032880"(regulation of protein localization)|sgd:YNL086W(identity)	-	-	crc64:33200D2F0F729DA1	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Z/Rium0Kwj3ZUHa4WE5PPksPXdg9606	rogid:XCPaHuGC9oKD/3W0gY5ZY8jKtFs559292	intact-crc:E247D3D6F64F9965|rigid:Nt9hHYoJV/gor2whzS37apTB0CM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48232	uniprotkb:Q96EV8	intact:EBI-28775|uniprotkb:D6W193|ensemblfungi:YNL086W	intact:EBI-465804|uniprotkb:Q5THY3|uniprotkb:Q5THY4|uniprotkb:Q96NV2|intact:EBI-28986386|ensembl:ENSP00000341680|uniprotkb:Q9H0U2|uniprotkb:Q9H3J5|uniprotkb:A8K3V3	psi-mi:snapn_yeast(display_long)|uniprotkb:YNL086W(locus name)|uniprotkb:N2254(orf name)|uniprotkb:SNN1(gene name)|psi-mi:SNN1(display_short)|uniprotkb:SNAPIN-like protein 1(gene name synonym)	psi-mi:dtbp1_human(display_long)|uniprotkb:My031(orf name)|uniprotkb:DTNBP1(gene name)|psi-mi:DTNBP1(display_short)|uniprotkb:Dystrobrevin-binding protein 1(gene name synonym)|uniprotkb:Hermansky-Pudlak syndrome 7 protein(gene name synonym)|uniprotkb:Dysbindin-1(gene name synonym)|uniprotkb:BLOC1S8(gene name synonym)|uniprotkb:Biogenesis of lysosome-related organelles complex 1 subunit 8(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11543129|imex:IM-24995-2191	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014313.1|sgd:S000005030|dip:DIP-1188N|mint:P48232|ensemblfungi:YNL086W(gene)|ensemblfungi:YNL086W_mRNA(transcript)|go:"GO:0005768"(endosome)|go:"GO:0007032"(endosome organization)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0032880"(regulation of protein localization)|sgd:YNL086W(identity)	ensembl:ENSG00000047579(gene)|ensembl:ENST00000344537(transcript)|go:"GO:0001956"(positive regulation of neurotransmitter secretion)|go:"GO:0005634"(nucleus)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007596"(blood coagulation)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014059"(regulation of dopamine secretion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016528"(sarcoplasm)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0030496"(midbody)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032438"(melanosome organization)|go:"GO:0033162"(melanosome membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0043005"(neuron projection)|go:"GO:0043197"(dendritic spine)|go:"GO:0005737"(cytoplasm)|go:"GO:0043506"(regulation of JUN kinase activity)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0060155"(platelet dense granule organization)|go:"GO:0060159"(regulation of dopamine receptor signaling pathway)|go:"GO:0071901"(negative regulation of protein serine/threonine kinase activity)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR007531(Dysbindin)|reactome:R-HSA-432722|go:"GO:0048490"(anterograde synaptic vesicle transport)|refseq:NP_115498.2|refseq:NP_898861.1|refseq:NP_001258597.1|refseq:NP_001258598.1|ensembl:ENST00000338950|ensembl:ENSP00000344718|ensembl:ENSP00000341680|refseq:NP_001258596.1|entrezgene/locuslink:84062(identity)	-	crc64:33200D2F0F729DA1	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:XCPaHuGC9oKD/3W0gY5ZY8jKtFs559292	rogid:PBwxp1vobm9l5yGoqev97lzkMHg9606	intact-crc:E48BF49580AA3B6D|rigid:G5QXP+d4EP28p40fQo/bbxOmhiQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96BD8	uniprotkb:P48232	intact:EBI-741854|uniprotkb:B2R9Y6|uniprotkb:B4E0P4|ensembl:ENSP00000285116|ensembl:ENSP00000381470|ensembl:ENSP00000458992|ensembl:ENSP00000478259	intact:EBI-28775|uniprotkb:D6W193|ensemblfungi:YNL086W	psi-mi:ska1_human(display_long)|uniprotkb:SKA1(gene name)|psi-mi:SKA1(display_short)|uniprotkb:C18orf24(gene name synonym)	psi-mi:snapn_yeast(display_long)|uniprotkb:YNL086W(locus name)|uniprotkb:N2254(orf name)|uniprotkb:SNN1(gene name)|psi-mi:SNN1(display_short)|uniprotkb:SNAPIN-like protein 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11543120|imex:IM-24995-2190	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001034624.1|refseq:NP_659497.1|ensembl:ENSG00000154839(gene)|ensembl:ENSG00000262634(gene)|ensembl:ENST00000285116(transcript)|ensembl:ENST00000398452(transcript)|ensembl:ENST00000571751(transcript)|ensembl:ENST00000616604(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000940"(outer kinetochore)|go:"GO:0005829"(cytosol)|go:"GO:0005876"(spindle microtubule)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008017"(microtubule binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0031110"(regulation of microtubule polymerization or depolymerization)|go:"GO:0051301"(cell division)|go:"GO:0072686"(mitotic spindle)|interpro:IPR009829(Protein of unknown function DUF1395)|interpro:IPR042031|mint:Q96BD8|rcsb pdb:4AJ5|rcsb pdb:4C9Y|rcsb pdb:4CA0|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|entrezgene/locuslink:220134(identity)	refseq:NP_014313.1|sgd:S000005030|dip:DIP-1188N|mint:P48232|ensemblfungi:YNL086W(gene)|ensemblfungi:YNL086W_mRNA(transcript)|go:"GO:0005768"(endosome)|go:"GO:0007032"(endosome organization)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0032880"(regulation of protein localization)|sgd:YNL086W(identity)	-	-	crc64:33200D2F0F729DA1	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Z7y57MeLsUJK0R9JNqHJNBbKr/89606	rogid:XCPaHuGC9oKD/3W0gY5ZY8jKtFs559292	intact-crc:8C128FA6D170F3D2|rigid:UB/Bin/IhLlBAU8regFNV3ErgzA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8NA61-2	uniprotkb:P48232	intact:EBI-11524851|ensembl:ENSP00000368249|ensembl:ENSP00000480148	intact:EBI-28775|uniprotkb:D6W193|ensemblfungi:YNL086W	psi-mi:q8na61-2(display_long)|uniprotkb:CBY2(gene name)|psi-mi:CBY2(display_short)|uniprotkb:SPERT(gene name synonym)|uniprotkb:Spermatid-associated protein(gene name synonym)	psi-mi:snapn_yeast(display_long)|uniprotkb:YNL086W(locus name)|uniprotkb:N2254(orf name)|uniprotkb:SNN1(gene name)|psi-mi:SNN1(display_short)|uniprotkb:SNAPIN-like protein 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11543111|imex:IM-24995-2189	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-741724(isoform-parent)|ensembl:ENSG00000174015(gene)|ensembl:ENST00000378966(transcript)|ensembl:ENST00000610924(transcript)|uniprotkb:Q8NA61-2(isoform-parent)|entrezgene/locuslink:220082(identity)	refseq:NP_014313.1|sgd:S000005030|dip:DIP-1188N|mint:P48232|ensemblfungi:YNL086W(gene)|ensemblfungi:YNL086W_mRNA(transcript)|go:"GO:0005768"(endosome)|go:"GO:0007032"(endosome organization)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0032880"(regulation of protein localization)|sgd:YNL086W(identity)	-	-	crc64:33200D2F0F729DA1	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:SogYcXGGMYRYzB9xKC5o0pEtsDs9606	rogid:XCPaHuGC9oKD/3W0gY5ZY8jKtFs559292	intact-crc:263B8E7A09B51F7E|rigid:92+xr8GGy4qpJmxzQhTfRNYxDWE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48232	uniprotkb:Q8N6Y0	intact:EBI-28775|uniprotkb:D6W193|ensemblfungi:YNL086W	intact:EBI-739895|uniprotkb:Q8NBX7|uniprotkb:Q96KH3|uniprotkb:Q9BYI8|uniprotkb:A8K7L6|uniprotkb:B2RCR9|ensembl:ENSP00000252597	psi-mi:snapn_yeast(display_long)|uniprotkb:YNL086W(locus name)|uniprotkb:N2254(orf name)|uniprotkb:SNN1(gene name)|psi-mi:SNN1(display_short)|uniprotkb:SNAPIN-like protein 1(gene name synonym)	psi-mi:usbp1_human(display_long)|uniprotkb:USHBP1(gene name)|psi-mi:USHBP1(display_short)|uniprotkb:MCC-2(gene name synonym)|uniprotkb:AIE-75-binding protein(gene name synonym)|uniprotkb:AIEBP(gene name synonym)|uniprotkb:MCC2(gene name synonym)|uniprotkb:Mutated in colon cancer protein 2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11543102|imex:IM-24995-2188	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014313.1|sgd:S000005030|dip:DIP-1188N|mint:P48232|ensemblfungi:YNL086W(gene)|ensemblfungi:YNL086W_mRNA(transcript)|go:"GO:0005768"(endosome)|go:"GO:0007032"(endosome organization)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0032880"(regulation of protein localization)|sgd:YNL086W(identity)	refseq:NP_001284632.1|refseq:NP_114147.2|refseq:NP_001308346.1|ensembl:ENSG00000130307(gene)|ensembl:ENST00000252597(transcript)|go:"GO:0030165"(PDZ domain binding)|interpro:IPR019536|interpro:IPR040171|entrezgene/locuslink:83878(identity)	-	crc64:33200D2F0F729DA1	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:XCPaHuGC9oKD/3W0gY5ZY8jKtFs559292	rogid:vY1qx73Ju/z7WDu6k1kd10ZDVRo9606	intact-crc:0BBC6A06B7279F1F|rigid:DY0xKzsTS1LyJKp5ymhNiy00JT8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48232	uniprotkb:P37198	intact:EBI-28775|uniprotkb:D6W193|ensemblfungi:YNL086W	intact:EBI-347978|intact:EBI-28983799|ensembl:ENSP00000305503|ensembl:ENSP00000407331|ensembl:ENSP00000471191|ensembl:ENSP00000473192|uniprotkb:Q6GTM2|uniprotkb:Q503A4|uniprotkb:Q96C43|uniprotkb:Q9NSL1|uniprotkb:B3KWU5	psi-mi:snapn_yeast(display_long)|uniprotkb:YNL086W(locus name)|uniprotkb:N2254(orf name)|uniprotkb:SNN1(gene name)|psi-mi:SNN1(display_short)|uniprotkb:SNAPIN-like protein 1(gene name synonym)	psi-mi:nup62_human(display_long)|uniprotkb:NUP62(gene name)|psi-mi:NUP62(display_short)|uniprotkb:62 kDa nucleoporin(gene name synonym)|uniprotkb:Nucleoporin Nup62(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11543093|imex:IM-24995-2187	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014313.1|sgd:S000005030|dip:DIP-1188N|mint:P48232|ensemblfungi:YNL086W(gene)|ensemblfungi:YNL086W_mRNA(transcript)|go:"GO:0005768"(endosome)|go:"GO:0007032"(endosome organization)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0032880"(regulation of protein localization)|sgd:YNL086W(identity)	refseq:NP_714941.1|ensembl:ENSG00000213024(gene)|ensembl:ENST00000352066(transcript)|ensembl:ENST00000422090(transcript)|ensembl:ENST00000596217(transcript)|ensembl:ENST00000597029(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005642"(annulate lamellae)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007100"(mitotic centrosome separation)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007569"(cell aging)|go:"GO:0008219"(cell death)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0003682"(chromatin binding)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0019894"(kinesin binding)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042306"(regulation of protein import into nucleus)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043069"(negative regulation of programmed cell death)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045742"(positive regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046578"(regulation of Ras protein signal transduction)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0046601"(positive regulation of centriole replication)|go:"GO:0051028"(mRNA transport)|go:"GO:0051425"(PTB domain binding)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0072686"(mitotic spindle)|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|go:"GO:0090543"(Flemming body)|go:"GO:0098534"(centriole assembly)|go:"GO:1903438"(positive regulation of mitotic cytokinetic process)|go:"GO:1904781"(positive regulation of protein localization to centrosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR007758(Nucleoporin, Nsp1-like, C-terminal)|interpro:IPR026010|interpro:IPR033072|mint:P37198|rcsb pdb:2H4D|rcsb pdb:5IJN|rcsb pdb:5IJO|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|refseq:NP_714940.1|refseq:NP_001180286.1|refseq:NP_036478.2|refseq:NP_057637.2|ensembl:ENSP00000305503|ensembl:ENSP00000407331|ensembl:ENSP00000471191|ensembl:ENSP00000473192|dip:DIP-29749N|entrezgene/locuslink:23636(identity)	-	crc64:33200D2F0F729DA1	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:XCPaHuGC9oKD/3W0gY5ZY8jKtFs559292	rogid:v7mvKvTtVEnLMwcpUZIcdAzge009606	intact-crc:56F5E983446C313D|rigid:rpFh96J0kfVyT0N8FIrOoIJ+kmM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48837	uniprotkb:Q08379	intact:EBI-12324|ensemblfungi:YGR119C|uniprotkb:D6VUQ0	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	psi-mi:nup57_yeast(display_long)|uniprotkb:NUP57(gene name)|psi-mi:NUP57(display_short)|uniprotkb:YGR119C(locus name)|uniprotkb:G6320(orf name)|uniprotkb:Nuclear pore protein NUP57(gene name synonym)	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11543201|imex:IM-24995-2199	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YGR119C(gene)|ensemblfungi:YGR119C_mRNA(transcript)|go:"GO:0005643"(nuclear pore)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036228"(protein localization to nuclear inner membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0051028"(mRNA transport)|interpro:IPR024864|interpro:IPR025574|interpro:IPR025712|refseq:NP_011634.1|sgd:S000003351|mint:P48837|dip:DIP-866N|sgd:YGR119C(identity)	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N|entrezgene/locuslink:2801(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2017/05/26	rogid:ultDTflWHx7n/y2FrlWFf+lBKmw559292	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	intact-crc:E216E1354C91765A|rigid:lWusjqueKh0Hnk8R2KrjGBwfThU	false	-	sufficient binding region:383-1002	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q99598	uniprotkb:P48606	intact:EBI-742638|intact:EBI-1050136|uniprotkb:B1APC6|refseq:NP_005990|dip:DIP-29463N	intact:EBI-18991|uniprotkb:D6W2W5|ensemblfungi:YOR265W	psi-mi:tsnax_human(display_long)|uniprotkb:Translin-associated factor X(gene name synonym)|uniprotkb:TSNAX(gene name)|psi-mi:TSNAX(display_short)|uniprotkb:TRAX(gene name synonym)	psi-mi:tbca_yeast(display_long)|uniprotkb:YOR265W(locus name)|uniprotkb:RBL2(gene name)|psi-mi:RBL2(display_short)|uniprotkb:Tubulin-folding cofactor A(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11543192|imex:IM-24995-2198	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005634"(nucleus)|go:"GO:0008565"(obsolete protein transporter activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0007275"(multicellular organism development)|go:"GO:0007283"(spermatogenesis)|refseq:NP_005990.1|interpro:IPR002848(Translin)|interpro:IPR016068(Translin, N-terminal)|rcsb pdb:3PJA|rcsb pdb:3QB5|ensembl:ENST00000366639|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0031047"(gene silencing by RNA)|reactome:R-HSA-426486|go:"GO:0030422"(production of siRNA involved in RNA interference)|interpro:IPR036081|go:"GO:0003677"(DNA binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0046872"(metal ion binding)|go:"GO:0005829"(cytosol)|ensembl:ENSG00000116918|ensembl:ENSP00000355599|go:"GO:0005654"(nucleoplasm)|go:"GO:0003723"(RNA binding)|dip:DIP-29463N|mint:MINT-1347706|go:"GO:0044822"|interpro:IPR016069(Translin, C-terminal)|go:"GO:0031687"(A2A adenosine receptor binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0003697"(single-stranded DNA binding)|entrezgene/locuslink:7257(identity)	ensemblfungi:YOR265W(gene)|ensemblfungi:YOR265W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:0007023"(post-chaperonin tubulin folding pathway)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0015631"(tubulin binding)|go:"GO:0048487"(beta-tubulin binding)|interpro:IPR004226(Tubulin binding cofactor A)|interpro:IPR036126|rcsb pdb:1QSD|refseq:NP_014908.1|sgd:S000005791|dip:DIP-4101N|mint:P48606|sgd:YOR265W(identity)	-	crc64:D38B0DD96B50C0B9|no-uniprot-update:|caution:"The protein could not be merged with EBI-12908040 because of some conflicts with the protein sequence (features which cannot be shifted)."	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:TaNIxjLHGusdq32WbdJ21DG9yBQ9606	rogid:Qbjv1Un+CKyQZ+gTbJl7ETlkc9o559292	intact-crc:E158BF3FA120807F|rigid:SmxS0R0ePAiBfY3hx6PXEYderCQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O14641	uniprotkb:P48510	intact:EBI-740850|ensembl:ENSP00000005340|uniprotkb:Q53XM0|uniprotkb:D3DTN3	intact:EBI-6174|uniprotkb:D6W0A3|ensemblfungi:YMR276W	psi-mi:dvl2_human(display_long)|uniprotkb:DSH homolog 2(gene name synonym)|uniprotkb:DVL2(gene name)|psi-mi:DVL2(display_short)	psi-mi:dsk2_yeast(display_long)|uniprotkb:DSK2(gene name)|psi-mi:DSK2(display_short)|uniprotkb:SHE4(gene name synonym)|uniprotkb:YMR276W(locus name)|uniprotkb:YM8021.02(orf name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11543183|imex:IM-24995-2197	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004413.1|ensembl:ENSG00000004975(gene)|ensembl:ENST00000005340(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005109"(frizzled binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0007507"(heart development)|go:"GO:0016235"(aggresome)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044340"(canonical Wnt signaling pathway involved in regulation of cell proliferation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0150012"(positive regulation of neuron projection arborization)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008341(Dishevelled-2 region)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:O14641|rcsb pdb:2REY|rcsb pdb:3CBX|rcsb pdb:3CBY|rcsb pdb:3CBZ|rcsb pdb:3CC0|rcsb pdb:4WIP|rcsb pdb:5LNP|rcsb pdb:5SUY|rcsb pdb:5SUZ|rcsb pdb:6IW3|rcsb pdb:6JCK|reactome:R-HSA-201681|reactome:R-HSA-201688|reactome:R-HSA-2028269|reactome:R-HSA-4086400|reactome:R-HSA-4608870|reactome:R-HSA-4641258|reactome:R-HSA-4641262|reactome:R-HSA-5099900|reactome:R-HSA-5368598|reactome:R-HSA-5663220|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9673324|ensembl:ENSP00000005340|dip:DIP-34433N|entrezgene/locuslink:1856(identity)	refseq:NP_014003.1|sgd:S000004889|dip:DIP-4398N|mint:P48510|ensemblfungi:YMR276W(gene)|ensemblfungi:YMR276W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030474"(spindle pole body duplication)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0072665"(protein localization to vacuole)|interpro:IPR000626(Ubiquitin)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR019954|interpro:IPR029071|rcsb pdb:1WR1|rcsb pdb:2BWB|rcsb pdb:2BWE|rcsb pdb:2BWF|rcsb pdb:3M63|rcsb pdb:4UN2|reactome:R-SCE-8856825|sgd:YMR276W(identity)	-	-	crc64:3F8691BB95E46569	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:2Vdc8oRnT4Mz/j+EXQXrL3AszOc9606	rogid:1hHbfo970BiDc/ZuAO8Jc6V9vEI559292	intact-crc:3700DE7B1490F52E|rigid:OFBwQNwhklTLKJu+V2vrPLrktfw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UHV2	uniprotkb:P48362	intact:EBI-748601|uniprotkb:Q9BUE7|ensembl:ENSP00000350633	intact:EBI-8304|uniprotkb:D6VUX0|ensemblfungi:YGR187C	psi-mi:srtd1_human(display_long)|uniprotkb:Transcriptional regulator interacting with the PHD-bromodomain 1(gene name synonym)|uniprotkb:CDK4-binding protein p34SEI1(gene name synonym)|uniprotkb:SERTAD1(gene name)|psi-mi:SERTAD1(display_short)|uniprotkb:SEI1(gene name synonym)|uniprotkb:TRIPBR1(gene name synonym)	psi-mi:hgh1_yeast(display_long)|uniprotkb:HGH1(gene name)|psi-mi:HGH1(display_short)|uniprotkb:HMG1/2 protein homolog(gene name synonym)|uniprotkb:G7538(orf name)|uniprotkb:YGR187C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11543174|imex:IM-24995-2196	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_037508.2|ensembl:ENSG00000197019(gene)|ensembl:ENST00000357949(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048096"|interpro:IPR009263(SERTA)|mint:Q9UHV2|entrezgene/locuslink:29950(identity)	sgd:S000003419|refseq:NP_011703.3|mint:P48362|dip:DIP-4721N|ensemblfungi:YGR187C(gene)|ensemblfungi:YGR187C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0061770"(translation elongation factor binding)|interpro:IPR007205(Protein of unknown function DUF383)|interpro:IPR007206(Protein of unknown function DUF384)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR039717|rcsb pdb:6HB1|rcsb pdb:6HB2|rcsb pdb:6HB3|sgd:YGR187C(identity)	-	-	crc64:24D4EFAEBD5D7A48	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:40dvjniwxY/UQiyoVREicctpWe09606	rogid:YQkKPiBqhycG0Z+2lxERBLVdy1w559292	intact-crc:EFBA9AE8534245E8|rigid:kPL182n1L1WDQj5e2ABipEAp9dM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48362	uniprotkb:Q969G2	intact:EBI-8304|uniprotkb:D6VUX0|ensemblfungi:YGR187C	intact:EBI-2865388|uniprotkb:Q8NHM1|uniprotkb:Q969W2|uniprotkb:Q8TCJ1|uniprotkb:Q8NHE0|uniprotkb:Q8WWX2|ensembl:ENSP00000263726	psi-mi:hgh1_yeast(display_long)|uniprotkb:HGH1(gene name)|psi-mi:HGH1(display_short)|uniprotkb:HMG1/2 protein homolog(gene name synonym)|uniprotkb:G7538(orf name)|uniprotkb:YGR187C(locus name)	psi-mi:lhx4_human(display_long)|uniprotkb:LHX4(gene name)|psi-mi:LHX4(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11543165|imex:IM-24995-2195	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003419|refseq:NP_011703.3|mint:P48362|dip:DIP-4721N|ensemblfungi:YGR187C(gene)|ensemblfungi:YGR187C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0061770"(translation elongation factor binding)|interpro:IPR007205(Protein of unknown function DUF383)|interpro:IPR007206(Protein of unknown function DUF384)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR039717|rcsb pdb:6HB1|rcsb pdb:6HB2|rcsb pdb:6HB3|sgd:YGR187C(identity)	refseq:NP_203129.1|dip:DIP-29454N|ensembl:ENSG00000121454(gene)|ensembl:ENST00000263726(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001890"(placenta development)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0021526"(medial motor column neuron differentiation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|mint:Q969G2|rcsb pdb:5HOD|reactome:R-HSA-9010553|entrezgene/locuslink:89884(identity)	-	crc64:24D4EFAEBD5D7A48	crc64:6499F38E78B79FD1	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:YQkKPiBqhycG0Z+2lxERBLVdy1w559292	rogid:dCB3WgIBMdi0nNvaCFaioh+F9sw9606	intact-crc:EF932A62EF1DEAA6|rigid:+aolQ+4ablvd2k8Qys4GsTOkhZg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48232	uniprotkb:Q9NPJ6	intact:EBI-28775|uniprotkb:D6W193|ensemblfungi:YNL086W	intact:EBI-394607|uniprotkb:Q9BS95|uniprotkb:Q9NYR5|uniprotkb:Q53GB4|uniprotkb:Q53H68|uniprotkb:Q5T912|uniprotkb:Q6FHC4|uniprotkb:Q6IA79|uniprotkb:B4DX67|ensembl:ENSP00000258648	psi-mi:snapn_yeast(display_long)|uniprotkb:YNL086W(locus name)|uniprotkb:N2254(orf name)|uniprotkb:SNN1(gene name)|psi-mi:SNN1(display_short)|uniprotkb:SNAPIN-like protein 1(gene name synonym)	psi-mi:med4_human(display_long)|uniprotkb:HSPC126(orf name)|uniprotkb:DRIP36(gene name synonym)|uniprotkb:MED4(gene name)|psi-mi:MED4(display_short)|uniprotkb:ARC36(gene name synonym)|uniprotkb:Mediator complex subunit 4(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex 36 kDa component(gene name synonym)|uniprotkb:Activator-recruited cofactor 36 kDa component(gene name synonym)|uniprotkb:TRAP/SMCC/PC2 subunit p36 subunit(gene name synonym)|uniprotkb:VDRIP(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11543156|imex:IM-24995-2194	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014313.1|sgd:S000005030|dip:DIP-1188N|mint:P48232|ensemblfungi:YNL086W(gene)|ensemblfungi:YNL086W_mRNA(transcript)|go:"GO:0005768"(endosome)|go:"GO:0007032"(endosome organization)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0032880"(regulation of protein localization)|sgd:YNL086W(identity)	refseq:NP_001257558.1|refseq:NP_054885.1|ensembl:ENSG00000136146(gene)|ensembl:ENST00000258648(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0070847"(core mediator complex)|interpro:IPR019258|mint:Q9NPJ6|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|entrezgene/locuslink:29079(identity)	-	crc64:33200D2F0F729DA1	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:XCPaHuGC9oKD/3W0gY5ZY8jKtFs559292	rogid:Bept2Oec50gruA9e4pf+eEUiANM9606	intact-crc:6EAFFF9F39DDB56C|rigid:ZUrZqOehAmrIHlIcTMuqZVSdGYo	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48837	uniprotkb:Q5JR59-3	intact:EBI-12324|ensemblfungi:YGR119C|uniprotkb:D6VUQ0	intact:EBI-11522433|ensembl:ENSP00000370186	psi-mi:nup57_yeast(display_long)|uniprotkb:NUP57(gene name)|psi-mi:NUP57(display_short)|uniprotkb:YGR119C(locus name)|uniprotkb:G6320(orf name)|uniprotkb:Nuclear pore protein NUP57(gene name synonym)	psi-mi:q5jr59-3(display_long)|uniprotkb:MTUS2(gene name)|psi-mi:MTUS2(display_short)|uniprotkb:CAZIP(gene name synonym)|uniprotkb:Cardiac zipper protein(gene name synonym)|uniprotkb:KIAA0774(gene name synonym)|uniprotkb:Microtubule plus-end tracking protein TIP150(gene name synonym)|uniprotkb:TIP150(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11543259|imex:IM-24995-2205	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YGR119C(gene)|ensemblfungi:YGR119C_mRNA(transcript)|go:"GO:0005643"(nuclear pore)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036228"(protein localization to nuclear inner membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0051028"(mRNA transport)|interpro:IPR024864|interpro:IPR025574|interpro:IPR025712|refseq:NP_011634.1|sgd:S000003351|mint:P48837|dip:DIP-866N|sgd:YGR119C(identity)	ensembl:ENSG00000132938(gene)|ensembl:ENST00000380808(transcript)|intact:EBI-742948(isoform-parent)|uniprotkb:Q5JR59-3(isoform-parent)|entrezgene/locuslink:23281(identity)	-	-	isoform-comment:No experimental confirmation available.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:ultDTflWHx7n/y2FrlWFf+lBKmw559292	rogid:npId9tC7VoLN/jteoBiRbSYChPs9606	intact-crc:29302441A5EBF5A8|rigid:qPpBrX3s1J3WortwGo2VBLAlPzI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P43365	uniprotkb:P48837	intact:EBI-749530|uniprotkb:Q9NSD3|intact:EBI-10178394|uniprotkb:Q6FHH8|ensembl:ENSP00000350592|ensembl:ENSP00000377447|ensembl:ENSP00000377478	intact:EBI-12324|ensemblfungi:YGR119C|uniprotkb:D6VUQ0	psi-mi:magac_human(display_long)|uniprotkb:MAGE-12 antigen(gene name synonym)|uniprotkb:MAGE12F antigen(gene name synonym)|uniprotkb:Cancer/testis antigen 1.12(gene name synonym)|uniprotkb:MAGEA12(gene name)|psi-mi:MAGEA12(display_short)|uniprotkb:MAGE12(gene name synonym)	psi-mi:nup57_yeast(display_long)|uniprotkb:NUP57(gene name)|psi-mi:NUP57(display_short)|uniprotkb:YGR119C(locus name)|uniprotkb:G6320(orf name)|uniprotkb:Nuclear pore protein NUP57(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11543250|imex:IM-24995-2204	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001159858.1|refseq:NP_001159859.1|refseq:NP_005358.2|ensembl:ENSG00000213401(gene)|ensembl:ENST00000357916(transcript)|ensembl:ENST00000393869(transcript)|ensembl:ENST00000393900(transcript)|interpro:IPR002190(MAGE protein)|interpro:IPR021072|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|entrezgene/locuslink:4111(identity)	ensemblfungi:YGR119C(gene)|ensemblfungi:YGR119C_mRNA(transcript)|go:"GO:0005643"(nuclear pore)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036228"(protein localization to nuclear inner membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0051028"(mRNA transport)|interpro:IPR024864|interpro:IPR025574|interpro:IPR025712|refseq:NP_011634.1|sgd:S000003351|mint:P48837|dip:DIP-866N|sgd:YGR119C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:3/Jxz2VsFOb67RWqWj3xbTrw3s49606	rogid:ultDTflWHx7n/y2FrlWFf+lBKmw559292	intact-crc:B8271ADF654EBBAD|rigid:RsooH0U2Ig2+KcoPlyd4E/fjdww	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P37198	uniprotkb:P48837	intact:EBI-347978|intact:EBI-28983799|ensembl:ENSP00000305503|ensembl:ENSP00000407331|ensembl:ENSP00000471191|ensembl:ENSP00000473192|uniprotkb:Q6GTM2|uniprotkb:Q503A4|uniprotkb:Q96C43|uniprotkb:Q9NSL1|uniprotkb:B3KWU5	intact:EBI-12324|ensemblfungi:YGR119C|uniprotkb:D6VUQ0	psi-mi:nup62_human(display_long)|uniprotkb:NUP62(gene name)|psi-mi:NUP62(display_short)|uniprotkb:62 kDa nucleoporin(gene name synonym)|uniprotkb:Nucleoporin Nup62(gene name synonym)	psi-mi:nup57_yeast(display_long)|uniprotkb:NUP57(gene name)|psi-mi:NUP57(display_short)|uniprotkb:YGR119C(locus name)|uniprotkb:G6320(orf name)|uniprotkb:Nuclear pore protein NUP57(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11543241|imex:IM-24995-2203	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_714941.1|ensembl:ENSG00000213024(gene)|ensembl:ENST00000352066(transcript)|ensembl:ENST00000422090(transcript)|ensembl:ENST00000596217(transcript)|ensembl:ENST00000597029(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005642"(annulate lamellae)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007100"(mitotic centrosome separation)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007569"(cell aging)|go:"GO:0008219"(cell death)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0003682"(chromatin binding)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0019894"(kinesin binding)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042306"(regulation of protein import into nucleus)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043069"(negative regulation of programmed cell death)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045742"(positive regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046578"(regulation of Ras protein signal transduction)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0046601"(positive regulation of centriole replication)|go:"GO:0051028"(mRNA transport)|go:"GO:0051425"(PTB domain binding)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0072686"(mitotic spindle)|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|go:"GO:0090543"(Flemming body)|go:"GO:0098534"(centriole assembly)|go:"GO:1903438"(positive regulation of mitotic cytokinetic process)|go:"GO:1904781"(positive regulation of protein localization to centrosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR007758(Nucleoporin, Nsp1-like, C-terminal)|interpro:IPR026010|interpro:IPR033072|mint:P37198|rcsb pdb:2H4D|rcsb pdb:5IJN|rcsb pdb:5IJO|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|refseq:NP_714940.1|refseq:NP_001180286.1|refseq:NP_036478.2|refseq:NP_057637.2|ensembl:ENSP00000305503|ensembl:ENSP00000407331|ensembl:ENSP00000471191|ensembl:ENSP00000473192|dip:DIP-29749N|entrezgene/locuslink:23636(identity)	ensemblfungi:YGR119C(gene)|ensemblfungi:YGR119C_mRNA(transcript)|go:"GO:0005643"(nuclear pore)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036228"(protein localization to nuclear inner membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0051028"(mRNA transport)|interpro:IPR024864|interpro:IPR025574|interpro:IPR025712|refseq:NP_011634.1|sgd:S000003351|mint:P48837|dip:DIP-866N|sgd:YGR119C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:v7mvKvTtVEnLMwcpUZIcdAzge009606	rogid:ultDTflWHx7n/y2FrlWFf+lBKmw559292	intact-crc:3C1A7756F9386429|rigid:VKD44/kn1QgtmQW8jZJ27AtTQoA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P19012	uniprotkb:P48837	intact:EBI-739566|uniprotkb:Q53XV8|uniprotkb:Q9BUG4|uniprotkb:B3KQY1|uniprotkb:B3KRA2|uniprotkb:E0CX14|ensembl:ENSP00000254043|ensembl:ENSP00000377546	intact:EBI-12324|ensemblfungi:YGR119C|uniprotkb:D6VUQ0	psi-mi:k1c15_human(display_long)|uniprotkb:KRT15(gene name)|psi-mi:KRT15(display_short)|uniprotkb:KRTB(gene name synonym)|uniprotkb:Cytokeratin-15(gene name synonym)|uniprotkb:Keratin-15(gene name synonym)	psi-mi:nup57_yeast(display_long)|uniprotkb:NUP57(gene name)|psi-mi:NUP57(display_short)|uniprotkb:YGR119C(locus name)|uniprotkb:G6320(orf name)|uniprotkb:Nuclear pore protein NUP57(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11543232|imex:IM-24995-2202	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002266.2|ensembl:ENSG00000171346(gene)|ensembl:ENST00000254043(transcript)|ensembl:ENST00000393976(transcript)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0008544"(epidermis development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097110"(scaffold protein binding)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR039008|mint:P19012|reactome:R-HSA-6805567|reactome:R-HSA-6809371|entrezgene/locuslink:3866(identity)	ensemblfungi:YGR119C(gene)|ensemblfungi:YGR119C_mRNA(transcript)|go:"GO:0005643"(nuclear pore)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036228"(protein localization to nuclear inner membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0051028"(mRNA transport)|interpro:IPR024864|interpro:IPR025574|interpro:IPR025712|refseq:NP_011634.1|sgd:S000003351|mint:P48837|dip:DIP-866N|sgd:YGR119C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:WrZQBYQvrWcfrR5ojWXrXp6spPE9606	rogid:ultDTflWHx7n/y2FrlWFf+lBKmw559292	intact-crc:1334CC140620FF62|rigid:EWdg0xHy45l7+DZ8VcH2+fSyZqU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48837	uniprotkb:P13196	intact:EBI-12324|ensemblfungi:YGR119C|uniprotkb:D6VUQ0	intact:EBI-3905054|ensembl:ENSP00000309259|ensembl:ENSP00000378416|ensembl:ENSP00000417719|ensembl:ENSP00000418779	psi-mi:nup57_yeast(display_long)|uniprotkb:NUP57(gene name)|psi-mi:NUP57(display_short)|uniprotkb:YGR119C(locus name)|uniprotkb:G6320(orf name)|uniprotkb:Nuclear pore protein NUP57(gene name synonym)	psi-mi:hem1_human(display_long)|uniprotkb:ALAS1(gene name)|psi-mi:ALAS1(display_short)|uniprotkb:ALAS3(gene name synonym)|uniprotkb:ALASH(gene name synonym)|uniprotkb:5-aminolevulinic acid synthase 1(gene name synonym)|uniprotkb:Delta-ALA synthase 1(gene name synonym)|uniprotkb:Delta-aminolevulinate synthase 1(gene name synonym)|uniprotkb:OK/SW-cl.121(orf name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11543223|imex:IM-24995-2201	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YGR119C(gene)|ensemblfungi:YGR119C_mRNA(transcript)|go:"GO:0005643"(nuclear pore)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036228"(protein localization to nuclear inner membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0051028"(mRNA transport)|interpro:IPR024864|interpro:IPR025574|interpro:IPR025712|refseq:NP_011634.1|sgd:S000003351|mint:P48837|dip:DIP-866N|sgd:YGR119C(identity)	refseq:NP_001291372.1|refseq:NP_001291373.1|refseq:NP_000679.1|refseq:NP_954635.1|go:"GO:0006783"(heme biosynthetic process)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0042541"(hemoglobin biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0048821"(erythrocyte development)|ensembl:ENSG00000023330(gene)|ensembl:ENST00000310271(transcript)|ensembl:ENST00000394965(transcript)|ensembl:ENST00000469224(transcript)|ensembl:ENST00000484952(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0003870"(5-aminolevulinate synthase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|interpro:IPR001917(Aminotransferase, class-II, pyridoxal-phosphate binding site)|interpro:IPR004839(Aminotransferase, class I and II)|interpro:IPR010961(Tetrapyrrole biosynthesis, 5-aminolevulinic acid synthase)|interpro:IPR015118(5-aminolevulinate synthase presequence)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|mint:P13196|reactome:R-HSA-189451|reactome:R-HSA-1989781|reactome:R-HSA-2151201|go:"GO:0006782"(protoporphyrinogen IX biosynthetic process)|entrezgene/locuslink:211(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:ultDTflWHx7n/y2FrlWFf+lBKmw559292	rogid:HFjJ6zrRF9UYD7LMB6A3CcxcS7c9606	intact-crc:8ACB9B231CF7BA05|rigid:55dkBZdItqxpdefbuIni1NTAFrc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q7Z6G3-2	uniprotkb:P48837	intact:EBI-10172876|ensembl:ENSP00000457354|intact:EBI-14062040	intact:EBI-12324|ensemblfungi:YGR119C|uniprotkb:D6VUQ0	psi-mi:q7z6g3-2(display_long)|uniprotkb:EFCBP2(gene name synonym)|uniprotkb:Neuronal calcium-binding protein 2(gene name synonym)|uniprotkb:Synaptotagmin-interacting protein 2(gene name synonym)|uniprotkb:NECAB2(gene name)|psi-mi:NECAB2(display_short)	psi-mi:nup57_yeast(display_long)|uniprotkb:NUP57(gene name)|psi-mi:NUP57(display_short)|uniprotkb:YGR119C(locus name)|uniprotkb:G6320(orf name)|uniprotkb:Nuclear pore protein NUP57(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11543212|imex:IM-24995-2200	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000103154(gene)|ensembl:ENST00000565691(transcript)|uniprotkb:Q7Z6G3-2(isoform-parent)|intact:EBI-950070(isoform-parent)|entrezgene/locuslink:54550(identity)	ensemblfungi:YGR119C(gene)|ensemblfungi:YGR119C_mRNA(transcript)|go:"GO:0005643"(nuclear pore)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036228"(protein localization to nuclear inner membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0051028"(mRNA transport)|interpro:IPR024864|interpro:IPR025574|interpro:IPR025712|refseq:NP_011634.1|sgd:S000003351|mint:P48837|dip:DIP-866N|sgd:YGR119C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:4S7oIx6h+mKzV3EPxqcfMNqaNko9606	rogid:ultDTflWHx7n/y2FrlWFf+lBKmw559292	intact-crc:706B69EF772B0600|rigid:2L/mQtHxIaS+bEFnqSRPYF5iGLE	false	sufficient binding region:65-303	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49955	uniprotkb:Q9UHX1-2	intact:EBI-664|uniprotkb:D6W0B5|ensemblfungi:YMR288W	intact:EBI-11529177|ensembl:ENSP00000322036|ensembl:ENSP00000478495	psi-mi:sf3b1_yeast(display_long)|uniprotkb:YMR288W(locus name)|uniprotkb:YM8021.14(orf name)|uniprotkb:HSH155(gene name)|psi-mi:HSH155(display_short)	psi-mi:q9uhx1-2(display_long)|uniprotkb:PUF60(gene name)|psi-mi:PUF60(display_short)|uniprotkb:"60 kDa poly(U)-binding-splicing factor"(gene name synonym)|uniprotkb:FIR(gene name synonym)|uniprotkb:FUSE-binding protein-interacting repressor(gene name synonym)|uniprotkb:ROBPI(gene name synonym)|uniprotkb:Ro-binding protein 1(gene name synonym)|uniprotkb:SIAHBP1(gene name synonym)|uniprotkb:Siah-binding protein 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11543332|imex:IM-24995-2213	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014015.1|sgd:S000004901|dip:DIP-2628N|mint:P49955|ensemblfungi:YMR288W(gene)|ensemblfungi:YMR288W_mRNA(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005686"(U2 snRNP)|go:"GO:0071004"(U2-type prespliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR038737|rcsb pdb:5GM6|rcsb pdb:5LQW|rcsb pdb:5NRL|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:6G90|sgd:YMR288W(identity)	intact:EBI-1053259(isoform-parent)|ensembl:ENSG00000179950(gene)|ensembl:ENSG00000274081(gene)|ensembl:ENST00000349157(transcript)|ensembl:ENST00000612237(transcript)|uniprotkb:Q9UHX1-2(isoform-parent)|entrezgene/locuslink:22827(identity)	-	crc64:27D26E4252A788E2	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:t0fwQOOum/AO/xL8vhZdF2EGymo559292	rogid:snVN9Lw5+MP2/aiq4z08ANwvr209606	intact-crc:E0159219A58365FA|rigid:+F97wpeDmVKWuj1/V1IUtVEp+iQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9H4P4	uniprotkb:P49723	intact:EBI-2130266|uniprotkb:B2RBT8|uniprotkb:O75598|intact:EBI-2563208|intact:EBI-11576203|uniprotkb:A6NFW0|ensembl:ENSP00000342755|ensembl:ENSP00000447303|ensembl:ENSP00000484671	intact:EBI-15251|uniprotkb:Q66R92|uniprotkb:D6VUW4|ensemblfungi:YGR180C	psi-mi:rnf41_human(display_long)|uniprotkb:RNF41(gene name)|psi-mi:RNF41(display_short)|uniprotkb:FLRF(gene name synonym)|uniprotkb:NRDP1(gene name synonym)|uniprotkb:RING finger protein 41(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase NRDP1(gene name synonym)|uniprotkb:SBBI03(orf name)	psi-mi:rir4_yeast(display_long)|uniprotkb:RNR4(gene name)|psi-mi:RNR4(display_short)|uniprotkb:YGR180C(locus name)|uniprotkb:CRT3(gene name synonym)|uniprotkb:Ribonucleotide reductase small subunit 2(gene name synonym)|uniprotkb:Ribonucleotide reductase R2 subunit 2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11543323|imex:IM-24995-2212	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011536036.1|refseq:XP_011536037.1|refseq:NP_001229755.1|refseq:NP_005776.1|refseq:NP_919340.1|refseq:NP_919339.1|refseq:XP_005268618.1|ensembl:ENSG00000181852(gene)|ensembl:ENST00000345093(transcript)|ensembl:ENST00000552656(transcript)|ensembl:ENST00000615206(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:2000377"(regulation of reactive oxygen species metabolic process)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013010(Zinc finger, SIAH-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR015036(USP8 interacting)|interpro:IPR017907|interpro:IPR037255|rcsb pdb:2FZP|rcsb pdb:2GWF|reactome:R-HSA-1358803|reactome:R-HSA-983168|entrezgene/locuslink:10193(identity)	sgd:S000003412|refseq:NP_011696.3|ensemblfungi:YGR180C(gene)|ensemblfungi:YGR180C_mRNA(transcript)|go:"GO:0004748"(ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005971"(ribonucleoside-diphosphate reductase complex)|go:"GO:0006260"(DNA replication)|go:"GO:0009263"(deoxyribonucleotide biosynthetic process)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR000358(Ribonucleotide reductase)|interpro:IPR012348(Ribonucleotide reductase-related)|interpro:IPR030475|interpro:IPR033909|rcsb pdb:1JK0|rcsb pdb:1SMS|rcsb pdb:1ZZD|interpro:IPR009078(Ferritin/ribonucleotide reductase-like)|dip:DIP-5381N|mint:P49723|sgd:YGR180C(identity)	-	-	crc64:712853F2D87D3972	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:jthVZwxUECSdqeJ2jZQ5UL28kDY9606	rogid:/Mx5xMzGpJSBsCDX8nwJMacQ6d4559292	intact-crc:597897B7B62A07C6|rigid:5hHeel0/IkqZUsqHDInWX+FA8ZQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P63279	uniprotkb:P49723	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	intact:EBI-15251|uniprotkb:Q66R92|uniprotkb:D6VUW4|ensemblfungi:YGR180C	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:rir4_yeast(display_long)|uniprotkb:RNR4(gene name)|psi-mi:RNR4(display_short)|uniprotkb:YGR180C(locus name)|uniprotkb:CRT3(gene name synonym)|uniprotkb:Ribonucleotide reductase small subunit 2(gene name synonym)|uniprotkb:Ribonucleotide reductase R2 subunit 2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11543314|imex:IM-24995-2211	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N|entrezgene/locuslink:7329(identity)	sgd:S000003412|refseq:NP_011696.3|ensemblfungi:YGR180C(gene)|ensemblfungi:YGR180C_mRNA(transcript)|go:"GO:0004748"(ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005971"(ribonucleoside-diphosphate reductase complex)|go:"GO:0006260"(DNA replication)|go:"GO:0009263"(deoxyribonucleotide biosynthetic process)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR000358(Ribonucleotide reductase)|interpro:IPR012348(Ribonucleotide reductase-related)|interpro:IPR030475|interpro:IPR033909|rcsb pdb:1JK0|rcsb pdb:1SMS|rcsb pdb:1ZZD|interpro:IPR009078(Ferritin/ribonucleotide reductase-like)|dip:DIP-5381N|mint:P49723|sgd:YGR180C(identity)	-	-	crc64:712853F2D87D3972	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	rogid:/Mx5xMzGpJSBsCDX8nwJMacQ6d4559292	intact-crc:2BA5F74C217D3630|rigid:B30fmCZAgY+r6nzkEimWDZSwJr8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49090	uniprotkb:P26641	intact:EBI-3048|uniprotkb:E9P8Y0|uniprotkb:D6VUQ6|ensemblfungi:YGR124W	intact:EBI-351467|uniprotkb:Q6PJ62|uniprotkb:Q6PK31|uniprotkb:Q96CU2|uniprotkb:Q9P196|intact:EBI-2321928|uniprotkb:B4DTG2|ensembl:ENSP00000331901	psi-mi:asns2_yeast(display_long)|uniprotkb:ASN2(gene name)|psi-mi:ASN2(display_short)|uniprotkb:YGR124W(locus name)|uniprotkb:G6358(orf name)|uniprotkb:Glutamine-dependent asparagine synthetase 2(gene name synonym)	psi-mi:ef1g_human(display_long)|uniprotkb:PRO1608(orf name)|uniprotkb:EEF1G(gene name)|psi-mi:EEF1G(display_short)|uniprotkb:EF1G(gene name synonym)|uniprotkb:eEF-1B gamma(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11543304|imex:IM-24995-2210	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011640.1|sgd:S000003356|dip:DIP-5189N|mint:P49090|ensemblfungi:YGR124W(gene)|ensemblfungi:YGR124W_mRNA(transcript)|go:"GO:0004066"("asparagine synthase (glutamine-hydrolyzing) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006529"(asparagine biosynthetic process)|go:"GO:0006541"(glutamine metabolic process)|go:"GO:0070981"(L-asparagine biosynthetic process)|interpro:IPR001962(Asparagine synthase)|interpro:IPR006426(Asparagine synthase, glutamine-hydrolyzing)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR017932|interpro:IPR029055|interpro:IPR033738|reactome:R-SCE-8963693|sgd:YGR124W(identity)	refseq:NP_001395.1|ensembl:ENSG00000254772(gene)|ensembl:ENST00000329251(transcript)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006414"(translational elongation)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001662(Translation elongation factor EF1B, gamma chain, conserved)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR036249|interpro:IPR036282|interpro:IPR036433|interpro:IPR040079|mint:P26641|rcsb pdb:1PBU|rcsb pdb:5DQS|rcsb pdb:5JPO|reactome:R-HSA-156842|dip:DIP-32516N|entrezgene/locuslink:1937(identity)	-	crc64:2809F3F0FEDE4183	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:h8FNSX14kWwOuKbbuLZsdxrqaXU559292	rogid:biVN96umeEdPm/wvPN4VwbSRHTs9606	intact-crc:BDBD90C93934BC4E|rigid:K8jmAk945MRBrNKC+V+zagQ14uU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q53EZ4	uniprotkb:P49089	intact:EBI-747776|uniprotkb:Q32WF5|uniprotkb:Q3MV20|uniprotkb:Q5VY28|uniprotkb:Q6N034|ensembl:ENSP00000360540|uniprotkb:Q96H32|uniprotkb:Q9NVS7|uniprotkb:B2RDG8|intact:EBI-10173536|uniprotkb:D3DR37|intact:EBI-28973801	intact:EBI-3043|uniprotkb:D6W4E2|ensemblfungi:YPR145W	psi-mi:cep55_human(display_long)|uniprotkb:Up-regulated in colon cancer 6(gene name synonym)|uniprotkb:CEP55(gene name)|psi-mi:CEP55(display_short)|uniprotkb:URCC6(gene name synonym)|uniprotkb:C10orf3(gene name synonym)	psi-mi:asns1_yeast(display_long)|uniprotkb:ASN1(gene name)|psi-mi:ASN1(display_short)|uniprotkb:YPR145W(locus name)|uniprotkb:P9659.3(orf name)|uniprotkb:Glutamine-dependent asparagine synthetase 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11543295|imex:IM-24995-2209	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001120654.1|refseq:NP_060601.3|ensembl:ENSG00000138180(gene)|ensembl:ENST00000371485(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0014066"(regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0030496"(midbody)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042802"(identical protein binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0061952"(midbody abscission)|go:"GO:0090543"(Flemming body)|go:"GO:1904888"(cranial skeletal system development)|interpro:IPR022008|interpro:IPR038926|mint:Q53EZ4|rcsb pdb:3E1R|rcsb pdb:3WUT|rcsb pdb:3WUU|rcsb pdb:3WUV|go:"GO:0005814"(centriole)|ensembl:ENSP00000360540|dip:DIP-44581N|entrezgene/locuslink:55165(identity)	refseq:NP_015471.1|sgd:S000006349|dip:DIP-3810N|reactome:R-SCE-8963693|ensemblfungi:YPR145W(gene)|ensemblfungi:YPR145W_mRNA(transcript)|go:"GO:0004066"("asparagine synthase (glutamine-hydrolyzing) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006529"(asparagine biosynthetic process)|go:"GO:0006541"(glutamine metabolic process)|go:"GO:0070981"(L-asparagine biosynthetic process)|interpro:IPR001962(Asparagine synthase)|interpro:IPR006426(Asparagine synthase, glutamine-hydrolyzing)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR017932|interpro:IPR029055|interpro:IPR033738|sgd:YPR145W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:tuo36vVb8ZgPDR81YjZFNEg559w9606	rogid:jel8vvbk1/PZHmUs57fDe2ybZ3Q559292	intact-crc:E94791C5A013974A|rigid:VoacHHA6wqVGluBP+KxT9eZssmY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q6RW13-2	uniprotkb:P49017	intact:EBI-11522760|ensembl:ENSP00000365816	intact:EBI-4937|ensemblfungi:YML110C|uniprotkb:D6W0H4	psi-mi:q6rw13-2(display_long)|uniprotkb:AGTRAP(gene name)|psi-mi:AGTRAP(display_short)|uniprotkb:AT1 receptor-associated protein(gene name synonym)|uniprotkb:ATRAP(gene name synonym)	psi-mi:coq5_yeast(display_long)|uniprotkb:COQ5(gene name)|psi-mi:COQ5(display_short)|uniprotkb:DBI56(gene name synonym)|uniprotkb:YML110C(locus name)|uniprotkb:YM8339.09C(orf name)|uniprotkb:Ubiquinone biosynthesis methyltransferase COQ5(gene name synonym)|uniprotkb:2-hexaprenyl-6-methoxy-1,4-benzoquinol methyltransferase(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11543286|imex:IM-24995-2208	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000177674(gene)|ensembl:ENST00000376629(transcript)|intact:EBI-741181(isoform-parent)|uniprotkb:Q6RW13-2(isoform-parent)|entrezgene/locuslink:57085(identity)	ensemblfungi:YML110C(gene)|ensemblfungi:YML110C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006744"(ubiquinone biosynthetic process)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0009060"(aerobic respiration)|go:"GO:0031314"(extrinsic component of mitochondrial inner membrane)|go:"GO:0032259"(methylation)|go:"GO:0043333"(2-octaprenyl-6-methoxy-1,4-benzoquinone methylase activity)|go:"GO:0043334"(2-hexaprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity)|interpro:IPR004033(UbiE/COQ5 methyltransferase)|interpro:IPR023576|interpro:IPR029063|rcsb pdb:4OBW|rcsb pdb:4OBX|refseq:NP_013597.1|sgd:S000004578|dip:DIP-1639N|sgd:YML110C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:PNzVis/8puQZBJ562gCqZKc078s9606	rogid:rgHxCUvCLn3xoq9Jv4EMhFupCmI559292	intact-crc:90804A0836E1CD26|rigid:2l2i9Qj0Zo0jzW6ribbZQlzU90w	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48837	uniprotkb:Q9NPJ6	intact:EBI-12324|ensemblfungi:YGR119C|uniprotkb:D6VUQ0	intact:EBI-394607|uniprotkb:Q9BS95|uniprotkb:Q9NYR5|uniprotkb:Q53GB4|uniprotkb:Q53H68|uniprotkb:Q5T912|uniprotkb:Q6FHC4|uniprotkb:Q6IA79|uniprotkb:B4DX67|ensembl:ENSP00000258648	psi-mi:nup57_yeast(display_long)|uniprotkb:NUP57(gene name)|psi-mi:NUP57(display_short)|uniprotkb:YGR119C(locus name)|uniprotkb:G6320(orf name)|uniprotkb:Nuclear pore protein NUP57(gene name synonym)	psi-mi:med4_human(display_long)|uniprotkb:HSPC126(orf name)|uniprotkb:DRIP36(gene name synonym)|uniprotkb:MED4(gene name)|psi-mi:MED4(display_short)|uniprotkb:ARC36(gene name synonym)|uniprotkb:Mediator complex subunit 4(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex 36 kDa component(gene name synonym)|uniprotkb:Activator-recruited cofactor 36 kDa component(gene name synonym)|uniprotkb:TRAP/SMCC/PC2 subunit p36 subunit(gene name synonym)|uniprotkb:VDRIP(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11543277|imex:IM-24995-2207	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YGR119C(gene)|ensemblfungi:YGR119C_mRNA(transcript)|go:"GO:0005643"(nuclear pore)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036228"(protein localization to nuclear inner membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0051028"(mRNA transport)|interpro:IPR024864|interpro:IPR025574|interpro:IPR025712|refseq:NP_011634.1|sgd:S000003351|mint:P48837|dip:DIP-866N|sgd:YGR119C(identity)	refseq:NP_001257558.1|refseq:NP_054885.1|ensembl:ENSG00000136146(gene)|ensembl:ENST00000258648(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0070847"(core mediator complex)|interpro:IPR019258|mint:Q9NPJ6|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|entrezgene/locuslink:29079(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:ultDTflWHx7n/y2FrlWFf+lBKmw559292	rogid:Bept2Oec50gruA9e4pf+eEUiANM9606	intact-crc:4EDCBC25C9690830|rigid:E4yC3H7ZNEmr16/ErOuydE6jpDM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48837	uniprotkb:Q8N6Y0	intact:EBI-12324|ensemblfungi:YGR119C|uniprotkb:D6VUQ0	intact:EBI-739895|uniprotkb:Q8NBX7|uniprotkb:Q96KH3|uniprotkb:Q9BYI8|uniprotkb:A8K7L6|uniprotkb:B2RCR9|ensembl:ENSP00000252597	psi-mi:nup57_yeast(display_long)|uniprotkb:NUP57(gene name)|psi-mi:NUP57(display_short)|uniprotkb:YGR119C(locus name)|uniprotkb:G6320(orf name)|uniprotkb:Nuclear pore protein NUP57(gene name synonym)	psi-mi:usbp1_human(display_long)|uniprotkb:USHBP1(gene name)|psi-mi:USHBP1(display_short)|uniprotkb:MCC-2(gene name synonym)|uniprotkb:AIE-75-binding protein(gene name synonym)|uniprotkb:AIEBP(gene name synonym)|uniprotkb:MCC2(gene name synonym)|uniprotkb:Mutated in colon cancer protein 2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11543268|imex:IM-24995-2206	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YGR119C(gene)|ensemblfungi:YGR119C_mRNA(transcript)|go:"GO:0005643"(nuclear pore)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036228"(protein localization to nuclear inner membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0051028"(mRNA transport)|interpro:IPR024864|interpro:IPR025574|interpro:IPR025712|refseq:NP_011634.1|sgd:S000003351|mint:P48837|dip:DIP-866N|sgd:YGR119C(identity)	refseq:NP_001284632.1|refseq:NP_114147.2|refseq:NP_001308346.1|ensembl:ENSG00000130307(gene)|ensembl:ENST00000252597(transcript)|go:"GO:0030165"(PDZ domain binding)|interpro:IPR019536|interpro:IPR040171|entrezgene/locuslink:83878(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:ultDTflWHx7n/y2FrlWFf+lBKmw559292	rogid:vY1qx73Ju/z7WDu6k1kd10ZDVRo9606	intact-crc:56A428DF485DC1E7|rigid:JZ0fyuEAWv0wjPEHyZnsVFCGo1M	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9NXK8	uniprotkb:P52286	intact:EBI-719790|uniprotkb:Q9H5K4|uniprotkb:B3KSJ8|ensembl:ENSP00000247977	intact:EBI-4090|uniprotkb:Q07186|uniprotkb:D6VSW0|ensemblfungi:YDR328C	psi-mi:fxl12_human(display_long)|uniprotkb:F-box and leucine-rich repeat protein 12(gene name synonym)|uniprotkb:F-box protein FBL12(gene name synonym)|uniprotkb:FBXL12(gene name)|psi-mi:FBXL12(display_short)|uniprotkb:FBL12(gene name synonym)	psi-mi:skp1_yeast(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:CBF3D(gene name synonym)|uniprotkb:YDR328C(locus name)|uniprotkb:D9798.14(orf name)|uniprotkb:Centromere DNA-binding protein complex CBF3 subunit D(gene name synonym)|uniprotkb:E3 ubiquitin ligase complex SCF subunit SKP1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11543382|imex:IM-24995-2218	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060173.1|refseq:NP_001303865.1|refseq:NP_001303866.1|refseq:NP_001303867.1|refseq:NP_001303868.1|refseq:NP_001303869.1|refseq:NP_001303870.1|refseq:NP_001303871.1|ensembl:ENSG00000127452(gene)|ensembl:ENST00000247977(transcript)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR032675|interpro:IPR036047|mint:Q9NXK8|reactome:R-HSA-8951664|reactome:R-HSA-983168|entrezgene/locuslink:54850(identity)	sgd:S000002736|refseq:NP_010615.3|dip:DIP-1236N|mint:P52286|ensemblfungi:YDR328C(gene)|ensemblfungi:YDR328C_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0000921"(septin ring assembly)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0010458"(exit from mitosis)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031518"(CBF3 complex)|go:"GO:0034622"|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0043291"(RAVE complex)|go:"GO:0045116"(protein neddylation)|go:"GO:0051382"(kinetochore assembly)|go:"GO:0097602"(cullin family protein binding)|go:"GO:2000766"(negative regulation of cytoplasmic translation)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|rcsb pdb:1NEX|rcsb pdb:3MKS|rcsb pdb:3V7D|rcsb pdb:5AN3|rcsb pdb:6F07|rcsb pdb:6FE8|rcsb pdb:6GSA|rcsb pdb:6GYP|rcsb pdb:6GYS|rcsb pdb:6GYU|rcsb pdb:7K79|reactome:R-SCE-174113|reactome:R-SCE-68949|reactome:R-SCE-8854050|reactome:R-SCE-8951664|reactome:R-SCE-983168|sgd:YDR328C(identity)	-	-	crc64:746DDE6470A69432	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:b+3vZLMbZvEww+hdTa3YnLkPiC49606	rogid:HO5Uz+KzzWNBubxoXRDNTVi8eIA559292	intact-crc:EE24D7C96352F5BA|rigid:YrtKB5yhPOVeqJBX+IeEhvzitc4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9NVF7	uniprotkb:P52286	intact:EBI-740282|uniprotkb:O75070|ensembl:ENSP00000355827|uniprotkb:E9PEM8	intact:EBI-4090|uniprotkb:Q07186|uniprotkb:D6VSW0|ensemblfungi:YDR328C	psi-mi:fbx28_human(display_long)|uniprotkb:FBXO28(gene name)|psi-mi:FBXO28(display_short)|uniprotkb:KIAA0483(gene name synonym)|uniprotkb:CENP-30(gene name synonym)	psi-mi:skp1_yeast(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:CBF3D(gene name synonym)|uniprotkb:YDR328C(locus name)|uniprotkb:D9798.14(orf name)|uniprotkb:Centromere DNA-binding protein complex CBF3 subunit D(gene name synonym)|uniprotkb:E3 ubiquitin ligase complex SCF subunit SKP1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11543373|imex:IM-24995-2217	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055991.1|ensembl:ENSG00000143756(gene)|ensembl:ENST00000366862(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000776"(kinetochore)|go:"GO:0042802"(identical protein binding)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR036047|interpro:IPR039719|refseq:NP_001129587.1|dip:DIP-56683N|entrezgene/locuslink:23219(identity)	sgd:S000002736|refseq:NP_010615.3|dip:DIP-1236N|mint:P52286|ensemblfungi:YDR328C(gene)|ensemblfungi:YDR328C_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0000921"(septin ring assembly)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0010458"(exit from mitosis)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031518"(CBF3 complex)|go:"GO:0034622"|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0043291"(RAVE complex)|go:"GO:0045116"(protein neddylation)|go:"GO:0051382"(kinetochore assembly)|go:"GO:0097602"(cullin family protein binding)|go:"GO:2000766"(negative regulation of cytoplasmic translation)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|rcsb pdb:1NEX|rcsb pdb:3MKS|rcsb pdb:3V7D|rcsb pdb:5AN3|rcsb pdb:6F07|rcsb pdb:6FE8|rcsb pdb:6GSA|rcsb pdb:6GYP|rcsb pdb:6GYS|rcsb pdb:6GYU|rcsb pdb:7K79|reactome:R-SCE-174113|reactome:R-SCE-68949|reactome:R-SCE-8854050|reactome:R-SCE-8951664|reactome:R-SCE-983168|sgd:YDR328C(identity)	-	-	crc64:746DDE6470A69432	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Iz7yI5ugv60KqYH7MAdBjXjw2vs9606	rogid:HO5Uz+KzzWNBubxoXRDNTVi8eIA559292	intact-crc:8E69078A2B4FEF2B|rigid:9LW09gw2oiP7ymssRKHBhvSsnlc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P50076	uniprotkb:Q96BA8	intact:EBI-7301533|intact:UNK-5379069|uniprotkb:D6VV08|ensemblfungi:YGR227W	intact:EBI-6942903|ensembl:ENSP00000481956|intact:MINT-268046|intact:MINT-8162577|uniprotkb:Q8N2D5|uniprotkb:Q96CP0	psi-mi:alg10_yeast(display_long)|uniprotkb:Alpha-1,2-glucosyltransferase ALG10-A(gene name synonym)|uniprotkb:DIE2(gene name)|psi-mi:DIE2(display_short)|uniprotkb:ALG10(gene name synonym)|uniprotkb:G8547(orf name)|uniprotkb:YGR227W(locus name)|uniprotkb:Alpha-2-glucosyltransferase ALG10(gene name synonym)|uniprotkb:Dolichyl-phosphoglucose-dependent glucosyltransferase ALG10(gene name synonym)|uniprotkb:Asparagine-linked glycosylation protein 10(gene name synonym)	psi-mi:cr3l1_human(display_long)|uniprotkb:CREB3L1(gene name)|psi-mi:CREB3L1(display_short)|uniprotkb:OASIS(gene name synonym)|uniprotkb:PSEC0238(orf name)|uniprotkb:Old astrocyte specifically-induced substance(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11543363|imex:IM-24995-2216	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003459|refseq:NP_011743.2|interpro:IPR016900(Alpha-1, 2 glucosyltransferase Alg10)|ensemblfungi:YGR227W(gene)|ensemblfungi:YGR227W_mRNA(transcript)|go:"GO:0004583"(dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0006488"(dolichol-linked oligosaccharide biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|go:"GO:0106073"(dolichyl pyrophosphate Glc2Man9GlcNAc2 alpha-1,2-glucosyltransferase activity)|sgd:YGR227W(identity)	ensembl:ENSG00000157613(gene)|ensembl:ENST00000621158(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0070278"(extracellular matrix constituent secretion)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029805|mint:Q96BA8|reactome:R-HSA-8874211|refseq:NP_443086.1|entrezgene/locuslink:90993(identity)	-	comment:mint|function:"Adds the third glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation. Transfers glucose from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide Glc(2)Man(9)GlcNAc(2)-PP-Dol"	comment:mint|function:"Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE"	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:CgcGK+aNZdx786YvH8/CbJHTirw559292	rogid:sMWUFmBeBBCO+T0Y2CuB/un1lBg9606	intact-crc:1CA5B859F6B7D4C9|rigid:tBHOTfqU6XaQ5rubwjPCIwnswLA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49955	uniprotkb:Q9UHX1-6	intact:EBI-664|uniprotkb:D6W0B5|ensemblfungi:YMR288W	intact:EBI-11085298|ensembl:ENSP00000431960	psi-mi:sf3b1_yeast(display_long)|uniprotkb:YMR288W(locus name)|uniprotkb:YM8021.14(orf name)|uniprotkb:HSH155(gene name)|psi-mi:HSH155(display_short)	psi-mi:q9uhx1-6(display_long)|uniprotkb:PUF60(gene name)|psi-mi:PUF60(display_short)|uniprotkb:"60 kDa poly(U)-binding-splicing factor"(gene name synonym)|uniprotkb:FIR(gene name synonym)|uniprotkb:FUSE-binding protein-interacting repressor(gene name synonym)|uniprotkb:ROBPI(gene name synonym)|uniprotkb:Ro-binding protein 1(gene name synonym)|uniprotkb:SIAHBP1(gene name synonym)|uniprotkb:Siah-binding protein 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11543352|imex:IM-24995-2215	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014015.1|sgd:S000004901|dip:DIP-2628N|mint:P49955|ensemblfungi:YMR288W(gene)|ensemblfungi:YMR288W_mRNA(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005686"(U2 snRNP)|go:"GO:0071004"(U2-type prespliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR038737|rcsb pdb:5GM6|rcsb pdb:5LQW|rcsb pdb:5NRL|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:6G90|sgd:YMR288W(identity)	ensembl:ENSG00000179950(gene)|ensembl:ENST00000527197(transcript)|intact:EBI-1053259(isoform-parent)|uniprotkb:Q9UHX1-6(isoform-parent)|entrezgene/locuslink:22827(identity)	-	crc64:27D26E4252A788E2	isoform-comment:"Contains a glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) at position 14."	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:t0fwQOOum/AO/xL8vhZdF2EGymo559292	rogid:rSsTImwmpEAWMCxLzF5Y4zVdeFM9606	intact-crc:A0EDD8D0A7FCB4C7|rigid:8EH56eX/wnavTFpdm70DHzxrVZI	false	-	sufficient binding region:15-513	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49955	uniprotkb:Q9UHX1-5	intact:EBI-664|uniprotkb:D6W0B5|ensemblfungi:YMR288W	intact:EBI-11526420|ensembl:ENSP00000395417|ensembl:ENSP00000478209	psi-mi:sf3b1_yeast(display_long)|uniprotkb:YMR288W(locus name)|uniprotkb:YM8021.14(orf name)|uniprotkb:HSH155(gene name)|psi-mi:HSH155(display_short)	psi-mi:q9uhx1-5(display_long)|uniprotkb:PUF60(gene name)|psi-mi:PUF60(display_short)|uniprotkb:"60 kDa poly(U)-binding-splicing factor"(gene name synonym)|uniprotkb:FIR(gene name synonym)|uniprotkb:FUSE-binding protein-interacting repressor(gene name synonym)|uniprotkb:ROBPI(gene name synonym)|uniprotkb:Ro-binding protein 1(gene name synonym)|uniprotkb:SIAHBP1(gene name synonym)|uniprotkb:Siah-binding protein 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11543341|imex:IM-24995-2214	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014015.1|sgd:S000004901|dip:DIP-2628N|mint:P49955|ensemblfungi:YMR288W(gene)|ensemblfungi:YMR288W_mRNA(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005686"(U2 snRNP)|go:"GO:0071004"(U2-type prespliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR038737|rcsb pdb:5GM6|rcsb pdb:5LQW|rcsb pdb:5NRL|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:6G90|sgd:YMR288W(identity)	intact:EBI-1053259(isoform-parent)|ensembl:ENSG00000179950(gene)|ensembl:ENSG00000274081(gene)|ensembl:ENST00000456095(transcript)|ensembl:ENST00000620953(transcript)|entrezgene/locuslink:22827(identity)	-	crc64:27D26E4252A788E2	isoform-comment:"Contains a glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) at position 14."	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:t0fwQOOum/AO/xL8vhZdF2EGymo559292	rogid:PSbIU++DIL6ysF0ccd3ZHzeJ5rs9606	intact-crc:D235E08C230E08E3|rigid:WDsds/ohoeSWpFKVxrSEtMUSDIU	false	-	sufficient binding region:15-530	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9BSE2	uniprotkb:P52870	intact:EBI-8649725|ensembl:ENSP00000295694|ensembl:ENSP00000384748|intact:MINT-8163648|uniprotkb:D3DVB8|uniprotkb:B2RE22	intact:EBI-16410|ensemblfungi:YER087C-B|uniprotkb:D3DLZ4	psi-mi:tmm79_human(display_long)|uniprotkb:MATT(gene name synonym)|uniprotkb:TMEM79(gene name)|psi-mi:TMEM79(display_short)|uniprotkb:Mattrin(gene name synonym)	psi-mi:sc6b1_yeast(display_long)|uniprotkb:Sec61 complex subunit SBH1(gene name synonym)|uniprotkb:YER087BC(orf name)|uniprotkb:YER087C-B(locus name)|uniprotkb:SBH1(gene name)|psi-mi:SBH1(display_short)|uniprotkb:SEB1(gene name synonym)|uniprotkb:Sec61 complex subunit beta(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11543440|imex:IM-24995-2224	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000163472(gene)|ensembl:ENST00000295694(transcript)|ensembl:ENST00000405535(transcript)|go:"GO:0002070"(epithelial cell maturation)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031069"(hair follicle morphogenesis)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0042335"(cuticle development)|go:"GO:0042802"(identical protein binding)|go:"GO:0045055"(regulated exocytosis)|go:"GO:0045684"(positive regulation of epidermis development)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070268"(cornification)|mint:Q9BSE2|refseq:NP_115699.1|entrezgene/locuslink:84283(identity)	ensemblfungi:YER087C-B(gene)|ensemblfungi:YER087C-B_mRNA(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|interpro:IPR016482(Preprotein translocase Sec, Sec61-beta subunit, eukarya)|interpro:IPR030671|rcsb pdb:6N3Q|rcsb pdb:6ND1|rcsb pdb:7AFT|rcsb pdb:7KAH|rcsb pdb:7KAI|sgd:S000002128|rcsb pdb:7KAJ|rcsb pdb:7KAO|rcsb pdb:7KAP|rcsb pdb:7KAQ|rcsb pdb:7KAR|rcsb pdb:7KAS|rcsb pdb:7KAT|rcsb pdb:7KAU|rcsb pdb:7KB5|refseq:NP_011011.3|dip:DIP-5681N|mint:P52870|sgd:YER087C-A(identity)	-	comment:mint	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:QdmILKEdTJzJUhBdigw/4vC4R3o9606	rogid:9cYnDPhmMpAOdB2GV5TxikzpjI0559292	intact-crc:DDBB2B21C596429C|rigid:cSjcXahvE4kqU+2ue6xd72Sc1Rg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96HH9	uniprotkb:P52870	intact:EBI-2832937|uniprotkb:Q9H753|uniprotkb:D3DSZ3|uniprotkb:B7Z1F2|uniprotkb:B7Z3R1|uniprotkb:B7Z6D8|uniprotkb:B7Z8T2|ensembl:ENSP00000285689	intact:EBI-16410|ensemblfungi:YER087C-B|uniprotkb:D3DLZ4	psi-mi:grm2b_human(display_long)|uniprotkb:GRAMD2B(gene name)|psi-mi:GRAMD2B(display_short)|uniprotkb:GRAMD3(gene name synonym)|uniprotkb:HCV NS3-transactivated protein 2(gene name synonym)|uniprotkb:NS3TP2(gene name synonym)	psi-mi:sc6b1_yeast(display_long)|uniprotkb:Sec61 complex subunit SBH1(gene name synonym)|uniprotkb:YER087BC(orf name)|uniprotkb:YER087C-B(locus name)|uniprotkb:SBH1(gene name)|psi-mi:SBH1(display_short)|uniprotkb:SEB1(gene name synonym)|uniprotkb:Sec61 complex subunit beta(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11543431|imex:IM-24995-2223	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_016865274.1|refseq:NP_001139791.1|refseq:NP_001139792.1|refseq:NP_001139793.1|refseq:NP_001139794.1|refseq:NP_076416.2|refseq:XP_005272120.1|ensembl:ENSG00000155324(gene)|ensembl:ENST00000285689(transcript)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0042802"(identical protein binding)|interpro:IPR004182(GRAM)|interpro:IPR011993(Pleckstrin homology-type)|entrezgene/locuslink:65983(identity)	ensemblfungi:YER087C-B(gene)|ensemblfungi:YER087C-B_mRNA(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|interpro:IPR016482(Preprotein translocase Sec, Sec61-beta subunit, eukarya)|interpro:IPR030671|rcsb pdb:6N3Q|rcsb pdb:6ND1|rcsb pdb:7AFT|rcsb pdb:7KAH|rcsb pdb:7KAI|sgd:S000002128|rcsb pdb:7KAJ|rcsb pdb:7KAO|rcsb pdb:7KAP|rcsb pdb:7KAQ|rcsb pdb:7KAR|rcsb pdb:7KAS|rcsb pdb:7KAT|rcsb pdb:7KAU|rcsb pdb:7KB5|refseq:NP_011011.3|dip:DIP-5681N|mint:P52870|sgd:YER087C-A(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:6UkVJddV5/mHpLX/rk00jMwCA+k9606	rogid:9cYnDPhmMpAOdB2GV5TxikzpjI0559292	intact-crc:40495AEBA5630FAD|rigid:yvhZg8l9r++wGI/kFZEEQLd35DU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P52870	uniprotkb:Q96G97-4	intact:EBI-16410|ensemblfungi:YER087C-B|uniprotkb:D3DLZ4	intact:EBI-10178113|ensembl:ENSP00000354032|ensembl:ENSP00000433888|ensembl:ENSP00000505838	psi-mi:sc6b1_yeast(display_long)|uniprotkb:Sec61 complex subunit SBH1(gene name synonym)|uniprotkb:YER087BC(orf name)|uniprotkb:YER087C-B(locus name)|uniprotkb:SBH1(gene name)|psi-mi:SBH1(display_short)|uniprotkb:SEB1(gene name synonym)|uniprotkb:Sec61 complex subunit beta(gene name synonym)	psi-mi:q96g97-4(display_long)|uniprotkb:Bernardinelli-Seip congenital lipodystrophy type 2 protein(gene name synonym)|uniprotkb:BSCL2(gene name)|psi-mi:BSCL2(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11543419|imex:IM-24995-2222	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YER087C-B(gene)|ensemblfungi:YER087C-B_mRNA(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|interpro:IPR016482(Preprotein translocase Sec, Sec61-beta subunit, eukarya)|interpro:IPR030671|rcsb pdb:6N3Q|rcsb pdb:6ND1|rcsb pdb:7AFT|rcsb pdb:7KAH|rcsb pdb:7KAI|sgd:S000002128|rcsb pdb:7KAJ|rcsb pdb:7KAO|rcsb pdb:7KAP|rcsb pdb:7KAQ|rcsb pdb:7KAR|rcsb pdb:7KAS|rcsb pdb:7KAT|rcsb pdb:7KAU|rcsb pdb:7KB5|refseq:NP_011011.3|dip:DIP-5681N|mint:P52870|sgd:YER087C-A(identity)	ensembl:ENSG00000168000(gene)|ensembl:ENST00000360796(transcript)|ensembl:ENST00000524862(transcript)|ensembl:ENST00000679883(transcript)|intact:EBI-741806(isoform-parent)|uniprotkb:Q96G97-4(isoform-parent)|entrezgene/locuslink:26580(identity)	-	-	isoform-comment:No experimental confirmation available.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:9cYnDPhmMpAOdB2GV5TxikzpjI0559292	rogid:Kewl3FQYPECmEGogRRGyAethllI9606	intact-crc:7BC8B6E20DD52D32|rigid:9CIBlAnJj1YRJCicuLOS1cjr4Xc	false	-	sufficient binding region:65-462	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96BA8	uniprotkb:P52870	intact:EBI-6942903|ensembl:ENSP00000481956|intact:MINT-268046|intact:MINT-8162577|uniprotkb:Q8N2D5|uniprotkb:Q96CP0	intact:EBI-16410|ensemblfungi:YER087C-B|uniprotkb:D3DLZ4	psi-mi:cr3l1_human(display_long)|uniprotkb:CREB3L1(gene name)|psi-mi:CREB3L1(display_short)|uniprotkb:OASIS(gene name synonym)|uniprotkb:PSEC0238(orf name)|uniprotkb:Old astrocyte specifically-induced substance(gene name synonym)	psi-mi:sc6b1_yeast(display_long)|uniprotkb:Sec61 complex subunit SBH1(gene name synonym)|uniprotkb:YER087BC(orf name)|uniprotkb:YER087C-B(locus name)|uniprotkb:SBH1(gene name)|psi-mi:SBH1(display_short)|uniprotkb:SEB1(gene name synonym)|uniprotkb:Sec61 complex subunit beta(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11543409|imex:IM-24995-2221	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157613(gene)|ensembl:ENST00000621158(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0070278"(extracellular matrix constituent secretion)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029805|mint:Q96BA8|reactome:R-HSA-8874211|refseq:NP_443086.1|entrezgene/locuslink:90993(identity)	ensemblfungi:YER087C-B(gene)|ensemblfungi:YER087C-B_mRNA(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|interpro:IPR016482(Preprotein translocase Sec, Sec61-beta subunit, eukarya)|interpro:IPR030671|rcsb pdb:6N3Q|rcsb pdb:6ND1|rcsb pdb:7AFT|rcsb pdb:7KAH|rcsb pdb:7KAI|sgd:S000002128|rcsb pdb:7KAJ|rcsb pdb:7KAO|rcsb pdb:7KAP|rcsb pdb:7KAQ|rcsb pdb:7KAR|rcsb pdb:7KAS|rcsb pdb:7KAT|rcsb pdb:7KAU|rcsb pdb:7KB5|refseq:NP_011011.3|dip:DIP-5681N|mint:P52870|sgd:YER087C-A(identity)	-	comment:mint|function:"Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE"	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:sMWUFmBeBBCO+T0Y2CuB/un1lBg9606	rogid:9cYnDPhmMpAOdB2GV5TxikzpjI0559292	intact-crc:0B905010A02D21F0|rigid:JJlwOt6m3hesNRsZyg8xVuaOAKY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q969F0	uniprotkb:P52870	intact:EBI-743099|ensembl:ENSP00000359375	intact:EBI-16410|ensemblfungi:YER087C-B|uniprotkb:D3DLZ4	psi-mi:fate1_human(display_long)|uniprotkb:Tumor antigen BJ-HCC-2(gene name synonym)|uniprotkb:Cancer/testis antigen 43(gene name synonym)|uniprotkb:FATE1(gene name)|psi-mi:FATE1(display_short)|uniprotkb:FATE(gene name synonym)	psi-mi:sc6b1_yeast(display_long)|uniprotkb:Sec61 complex subunit SBH1(gene name synonym)|uniprotkb:YER087BC(orf name)|uniprotkb:YER087C-B(locus name)|uniprotkb:SBH1(gene name)|psi-mi:SBH1(display_short)|uniprotkb:SEB1(gene name synonym)|uniprotkb:Sec61 complex subunit beta(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11543400|imex:IM-24995-2220	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_149076.1|ensembl:ENSG00000147378(gene)|ensembl:ENST00000370350(transcript)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|go:"GO:0051562"(negative regulation of mitochondrial calcium ion concentration)|interpro:IPR039153|interpro:IPR039433|mint:Q969F0|entrezgene/locuslink:89885(identity)	ensemblfungi:YER087C-B(gene)|ensemblfungi:YER087C-B_mRNA(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|interpro:IPR016482(Preprotein translocase Sec, Sec61-beta subunit, eukarya)|interpro:IPR030671|rcsb pdb:6N3Q|rcsb pdb:6ND1|rcsb pdb:7AFT|rcsb pdb:7KAH|rcsb pdb:7KAI|sgd:S000002128|rcsb pdb:7KAJ|rcsb pdb:7KAO|rcsb pdb:7KAP|rcsb pdb:7KAQ|rcsb pdb:7KAR|rcsb pdb:7KAS|rcsb pdb:7KAT|rcsb pdb:7KAU|rcsb pdb:7KB5|refseq:NP_011011.3|dip:DIP-5681N|mint:P52870|sgd:YER087C-A(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Nm1N6lO92MHr5rIKC007oouF5RE9606	rogid:9cYnDPhmMpAOdB2GV5TxikzpjI0559292	intact-crc:0C57C273CBF313BD|rigid:c0v+1AqiLG1L7oPfiRG1Ud9D9w8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P52870	uniprotkb:J3KQ12	intact:EBI-16410|ensemblfungi:YER087C-B|uniprotkb:D3DLZ4	intact:EBI-11532900|ensembl:ENSP00000385332	psi-mi:sc6b1_yeast(display_long)|uniprotkb:Sec61 complex subunit SBH1(gene name synonym)|uniprotkb:YER087BC(orf name)|uniprotkb:YER087C-B(locus name)|uniprotkb:SBH1(gene name)|psi-mi:SBH1(display_short)|uniprotkb:SEB1(gene name synonym)|uniprotkb:Sec61 complex subunit beta(gene name synonym)	psi-mi:j3kq12_human(display_long)|uniprotkb:hCG_2020143(orf name)|uniprotkb:BSCL2(gene name)|psi-mi:BSCL2(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11543391|imex:IM-24995-2219	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YER087C-B(gene)|ensemblfungi:YER087C-B_mRNA(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|interpro:IPR016482(Preprotein translocase Sec, Sec61-beta subunit, eukarya)|interpro:IPR030671|rcsb pdb:6N3Q|rcsb pdb:6ND1|rcsb pdb:7AFT|rcsb pdb:7KAH|rcsb pdb:7KAI|sgd:S000002128|rcsb pdb:7KAJ|rcsb pdb:7KAO|rcsb pdb:7KAP|rcsb pdb:7KAQ|rcsb pdb:7KAR|rcsb pdb:7KAS|rcsb pdb:7KAT|rcsb pdb:7KAU|rcsb pdb:7KB5|refseq:NP_011011.3|dip:DIP-5681N|mint:P52870|sgd:YER087C-A(identity)	ensembl:ENSG00000168000(gene)|ensembl:ENST00000405837(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019915"(lipid storage)|interpro:IPR009617(Protein of unknown function DUF1226)|entrezgene/locuslink:26580(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:9cYnDPhmMpAOdB2GV5TxikzpjI0559292	rogid:/q8SqeciXG5EVZxzVJRfX6gvRjY9606	intact-crc:530E1097BA2D11AD|rigid:Qy2mgAPlh4qPTWcLYn9Ed+TxEzo	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q5JST6	uniprotkb:P53038	intact:EBI-2349927|uniprotkb:Q9H653|uniprotkb:Q5JST8|uniprotkb:Q68DK4|uniprotkb:Q8NEI0|intact:EBI-28971886|ensembl:ENSP00000404232	intact:EBI-19106|uniprotkb:D6VUN1|ensemblfungi:YGR099W	psi-mi:efhc2_human(display_long)|uniprotkb:EFHC2(gene name)|psi-mi:EFHC2(display_short)	psi-mi:tel2_yeast(display_long)|uniprotkb:YGR099W(locus name)|uniprotkb:TEL2(gene name)|psi-mi:TEL2(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11543477|imex:IM-24995-2228	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000404232|refseq:NP_079460.2|ensembl:ENSG00000183690(gene)|ensembl:ENST00000420999(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005930"(axoneme)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0060285"(cilium-dependent cell motility)|go:"GO:0072686"(mitotic spindle)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR006602(Region of unknown function DM10)|interpro:IPR011992(EF-Hand type)|interpro:IPR040193|rcsb pdb:2Z13|rcsb pdb:2Z14|entrezgene/locuslink:80258(identity)	sgd:S000003331|ensemblfungi:YGR099W(gene)|ensemblfungi:YGR099W_mRNA(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0005829"(cytosol)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0034502"(protein localization to chromosome)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0070209"(ASTRA complex)|interpro:IPR019337|interpro:IPR038528|rcsb pdb:3O4Z|refseq:NP_011613.3|dip:DIP-1245N|mint:P53038|sgd:YGR099W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:O1XriQSkLcYkk7H7AlanQ1FKIBY9606	rogid:SZibPBili0M8YgHIwxf+sKkLk+M559292	intact-crc:E99904EA0E47C222|rigid:9giCatqt8PuQndlqWKpR+671cbI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8N6L0	uniprotkb:P53012	intact:EBI-749265|uniprotkb:Q96MC3|ensembl:ENSP00000404220	intact:EBI-16742|ensemblfungi:YGL126W|uniprotkb:E9P8W2|uniprotkb:D6VU22	psi-mi:kash5_human(display_long)|uniprotkb:KASH5(gene name)|psi-mi:KASH5(display_short)|uniprotkb:CCDC155(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 155(gene name synonym)|uniprotkb:KASH domain-containing protein 5(gene name synonym)	psi-mi:scs3_yeast(display_long)|uniprotkb:SCS3(gene name)|psi-mi:SCS3(display_short)|uniprotkb:YGL126W(locus name)|uniprotkb:G2868(orf name)|uniprotkb:FIT2B(gene name synonym)|uniprotkb:FIT family protein SCS3(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11543468|imex:IM-24995-2227	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_653289.3|ensembl:ENSG00000161609(gene)|ensembl:ENST00000447857(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034397"(telomere localization)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051225"(spindle assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0090172"(microtubule cytoskeleton organization involved in homologous chromosome segregation)|go:"GO:0090220"(chromosome localization to nuclear envelope involved in homologous chromosome segregation)|go:"GO:0090619"(meiotic spindle pole)|interpro:IPR011992(EF-Hand type)|interpro:IPR028168|interpro:IPR028170|interpro:IPR039508|mint:Q8N6L0|rcsb pdb:6R2I|rcsb pdb:6WMF|entrezgene/locuslink:147872(identity)	refseq:NP_011389.3|ensemblfungi:YGL126W(gene)|ensemblfungi:YGL126W_mRNA(transcript)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006644"(phospholipid metabolic process)|go:"GO:0008654"(phospholipid biosynthetic process)|go:"GO:0016818"(hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides)|go:"GO:0019915"(lipid storage)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0034389"(lipid droplet organization)|go:"GO:0140042"(lipid droplet formation)|go:"GO:1900480"(regulation of diacylglycerol biosynthetic process)|go:"GO:1900481"(negative regulation of diacylglycerol biosynthetic process)|interpro:IPR019388|go:"GO:0005783"(endoplasmic reticulum)|sgd:S000003094|reactome:R-SCE-8964572|dip:DIP-1209N|sgd:YGL126W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Wl9L7AcvDHCZuKjYLn8QgGIbZTc9606	rogid:Hv4EhOlOeuhRkn8ZMn7vejwqoag559292	intact-crc:1FDB0C3D0F98B2C9|rigid:AiGxQzGNJCywWak4v2aAkBXyVv4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P52917	uniprotkb:Q9HCM9-2	intact:EBI-20475|uniprotkb:D6W4H4|ensemblfungi:YPR173C	intact:EBI-11523450|ensembl:ENSP00000365847|ensembl:ENSP00000373095|ensembl:ENSP00000373097|ensembl:ENSP00000379797|ensembl:ENSP00000379800|ensembl:ENSP00000383486|ensembl:ENSP00000387445|ensembl:ENSP00000389198|ensembl:ENSP00000389852|ensembl:ENSP00000392130|ensembl:ENSP00000394353|ensembl:ENSP00000396986|ensembl:ENSP00000398956|ensembl:ENSP00000401071|ensembl:ENSP00000401184|ensembl:ENSP00000404340|ensembl:ENSP00000404904|ensembl:ENSP00000411582|ensembl:ENSP00000412743|ensembl:ENSP00000414525|ensembl:ENSP00000415259	psi-mi:vps4_yeast(display_long)|uniprotkb:VPS4(gene name)|psi-mi:VPS4(display_short)|uniprotkb:CSC1(gene name synonym)|uniprotkb:END13(gene name synonym)|uniprotkb:GRD13(gene name synonym)|uniprotkb:DID6(gene name synonym)|uniprotkb:Protein END13(gene name synonym)|uniprotkb:DOA4-independent degradation protein 6(gene name synonym)|uniprotkb:Vacuolar protein-targeting protein 10(gene name synonym)|uniprotkb:VPL4(gene name synonym)|uniprotkb:VPT10(gene name synonym)|uniprotkb:P9705.10(orf name)|uniprotkb:YPR173C(locus name)	psi-mi:q9hcm9-2(display_long)|uniprotkb:TRIM39(gene name)|psi-mi:TRIM39(display_short)|uniprotkb:RING finger protein 23(gene name synonym)|uniprotkb:RNF23(gene name synonym)|uniprotkb:TFP(gene name synonym)|uniprotkb:Testis-abundant finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 39(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM39(gene name synonym)|uniprotkb:TIM39beta(isoform synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11543458|imex:IM-24995-2226	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015499.1|sgd:S000006377|ensemblfungi:YPR173C(gene)|ensemblfungi:YPR173C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0007033"(vacuole organization)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0016197"(endosomal transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045053"(protein retention in Golgi apparatus)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0061709"(reticulophagy)|go:"GO:0070676"(intralumenal vesicle formation)|go:"GO:1990621"(ESCRT IV complex)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR007330(MIT)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR027417|interpro:IPR036181|rcsb pdb:2QP9|rcsb pdb:2QPA|rcsb pdb:2RKO|rcsb pdb:2V6X|rcsb pdb:3EIE|rcsb pdb:3EIH|rcsb pdb:3MHV|rcsb pdb:4NIQ|rcsb pdb:5FVK|rcsb pdb:5FVL|rcsb pdb:5UIE|rcsb pdb:5XMI|rcsb pdb:5XMK|rcsb pdb:6AP1|rcsb pdb:6BMF|rcsb pdb:6NDY|rcsb pdb:6OO2|reactome:R-SCE-917729|reactome:R-SCE-9668328|dip:DIP-1746N|mint:P52917|sgd:YPR173C(identity)	intact:EBI-739510(isoform-parent)|ensembl:ENSG00000204599(gene)|ensembl:ENSG00000206495(gene)|ensembl:ENSG00000224994(gene)|ensembl:ENSG00000226437(gene)|ensembl:ENSG00000229929(gene)|ensembl:ENSG00000230308(gene)|ensembl:ENSG00000232839(gene)|ensembl:ENST00000376659(transcript)|ensembl:ENST00000383601(transcript)|ensembl:ENST00000383603(transcript)|ensembl:ENST00000396548(transcript)|ensembl:ENST00000396551(transcript)|ensembl:ENST00000400644(transcript)|ensembl:ENST00000414015(transcript)|ensembl:ENST00000419790(transcript)|ensembl:ENST00000430502(transcript)|ensembl:ENST00000431272(transcript)|ensembl:ENST00000433900(transcript)|ensembl:ENST00000438076(transcript)|ensembl:ENST00000438859(transcript)|ensembl:ENST00000440117(transcript)|ensembl:ENST00000443109(transcript)|ensembl:ENST00000446397(transcript)|ensembl:ENST00000449318(transcript)|ensembl:ENST00000450778(transcript)|ensembl:ENST00000451132(transcript)|ensembl:ENST00000452705(transcript)|ensembl:ENST00000458607(transcript)|uniprotkb:Q9HCM9-2(isoform-parent)|entrezgene/locuslink:56658(identity)	-	crc64:E65BCDB19C9510DD	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:qXGTfZcBZ9jWOVjm6tl3wIR/ngM559292	rogid:UfSn2+IVRxtGomVeDGdZpL7mz5I9606	intact-crc:F4C3BF95AF2E4BEF|rigid:QNirPDE+f0Ap2Ljj1NcZWn7j2PE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P52917	uniprotkb:Q5T124-6	intact:EBI-20475|uniprotkb:D6W4H4|ensemblfungi:YPR173C	intact:EBI-11524408	psi-mi:vps4_yeast(display_long)|uniprotkb:VPS4(gene name)|psi-mi:VPS4(display_short)|uniprotkb:CSC1(gene name synonym)|uniprotkb:END13(gene name synonym)|uniprotkb:GRD13(gene name synonym)|uniprotkb:DID6(gene name synonym)|uniprotkb:Protein END13(gene name synonym)|uniprotkb:DOA4-independent degradation protein 6(gene name synonym)|uniprotkb:Vacuolar protein-targeting protein 10(gene name synonym)|uniprotkb:VPL4(gene name synonym)|uniprotkb:VPT10(gene name synonym)|uniprotkb:P9705.10(orf name)|uniprotkb:YPR173C(locus name)	psi-mi:q5t124-6(display_long)|uniprotkb:UBXN11(gene name)|psi-mi:UBXN11(display_short)|uniprotkb:Colorectal tumor-associated antigen COA-1(gene name synonym)|uniprotkb:SOC(gene name synonym)|uniprotkb:Socius(gene name synonym)|uniprotkb:UBX domain-containing protein 5(gene name synonym)|uniprotkb:UBXD5(gene name synonym)|uniprotkb:PP2243(orf name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11543449|imex:IM-24995-2225	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015499.1|sgd:S000006377|ensemblfungi:YPR173C(gene)|ensemblfungi:YPR173C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0007033"(vacuole organization)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0016197"(endosomal transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045053"(protein retention in Golgi apparatus)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0061709"(reticulophagy)|go:"GO:0070676"(intralumenal vesicle formation)|go:"GO:1990621"(ESCRT IV complex)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR007330(MIT)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR027417|interpro:IPR036181|rcsb pdb:2QP9|rcsb pdb:2QPA|rcsb pdb:2RKO|rcsb pdb:2V6X|rcsb pdb:3EIE|rcsb pdb:3EIH|rcsb pdb:3MHV|rcsb pdb:4NIQ|rcsb pdb:5FVK|rcsb pdb:5FVL|rcsb pdb:5UIE|rcsb pdb:5XMI|rcsb pdb:5XMK|rcsb pdb:6AP1|rcsb pdb:6BMF|rcsb pdb:6NDY|rcsb pdb:6OO2|reactome:R-SCE-917729|reactome:R-SCE-9668328|dip:DIP-1746N|mint:P52917|sgd:YPR173C(identity)	intact:EBI-746004(isoform-parent)|uniprotkb:Q5T124-6(isoform-parent)|entrezgene/locuslink:91544(identity)	-	crc64:E65BCDB19C9510DD	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:qXGTfZcBZ9jWOVjm6tl3wIR/ngM559292	rogid:1YSjG/p2ihcjl4P8KdPCaX2HxiY9606	intact-crc:69F54147CB968C29|rigid:7O1nNDYAqyasMOpQILRuAfgc7y0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P43355	uniprotkb:P53102	intact:EBI-740978|ensembl:ENSP00000349085|uniprotkb:O00346|uniprotkb:B2RC81	intact:EBI-24091|uniprotkb:D6VTX1|ensemblfungi:YGL183C	psi-mi:maga1_human(display_long)|uniprotkb:MAGE-1 antigen(gene name synonym)|uniprotkb:Antigen MZ2-E(gene name synonym)|uniprotkb:Cancer/testis antigen 1.1(gene name synonym)|uniprotkb:MAGEA1(gene name)|psi-mi:MAGEA1(display_short)|uniprotkb:MAGE1(gene name synonym)|uniprotkb:MAGE1A(gene name synonym)	psi-mi:mnd1_yeast(display_long)|uniprotkb:MND1(gene name)|psi-mi:MND1(display_short)|uniprotkb:G1604(orf name)|uniprotkb:YGL183C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11543526|imex:IM-24995-2233	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004979.3|ensembl:ENSG00000198681(gene)|ensembl:ENST00000356661(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|interpro:IPR002190(MAGE protein)|interpro:IPR021072|interpro:IPR030093|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|rcsb pdb:1W72|rcsb pdb:3BO8|dip:DIP-54794N|entrezgene/locuslink:4100(identity)	refseq:NP_011332.2|sgd:S000003151|dip:DIP-2673N|ensemblfungi:YGL183C(gene)|ensemblfungi:YGL183C_mRNA(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0007131"(reciprocal meiotic recombination)|interpro:IPR005647(meiotic nuclear division protein 1)|interpro:IPR040453|interpro:IPR040661|sgd:YGL183C(identity)	-	crc64:544EEB1F9F4E9D33	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:6XW3mnTNM3yvOtXmiFbU8Uz3hjA9606	rogid:wGVAo4LTwqSnDsJ+/xC3qIMqZ0k559292	intact-crc:7D138B85BB8BF068|rigid:B89B+XW3buuhr1+8kP6E7kSredc	false	-	sufficient binding region:46-219	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96BA8	uniprotkb:P53053	intact:EBI-6942903|ensembl:ENSP00000481956|intact:MINT-268046|intact:MINT-8162577|uniprotkb:Q8N2D5|uniprotkb:Q96CP0	intact:EBI-5002|uniprotkb:D6VV71|ensemblfungi:YGL263W	psi-mi:cr3l1_human(display_long)|uniprotkb:CREB3L1(gene name)|psi-mi:CREB3L1(display_short)|uniprotkb:OASIS(gene name synonym)|uniprotkb:PSEC0238(orf name)|uniprotkb:Old astrocyte specifically-induced substance(gene name synonym)	psi-mi:cos12_yeast(display_long)|uniprotkb:COS12(gene name)|psi-mi:COS12(display_short)|uniprotkb:NRC380(orf name)|uniprotkb:YGL263W(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11543517|imex:IM-24995-2232	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157613(gene)|ensembl:ENST00000621158(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0070278"(extracellular matrix constituent secretion)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029805|mint:Q96BA8|reactome:R-HSA-8874211|refseq:NP_443086.1|entrezgene/locuslink:90993(identity)	sgd:S000003232|refseq:NP_011251.1|dip:DIP-5034N|mint:P53053|ensemblfungi:YGL263W(gene)|ensemblfungi:YGL263W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005768"(endosome)|go:"GO:0016021"(integral component of membrane)|go:"GO:0043328"(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|interpro:IPR001142(Yeast membrane protein DUP)|sgd:YGL263W(identity)	-	comment:mint|function:"Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE"	crc64:52F58F4E400CA596	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:sMWUFmBeBBCO+T0Y2CuB/un1lBg9606	rogid:SqJH5ysFjpteLzoBp61CbATkXt8559292	intact-crc:902D54897F5373D0|rigid:IuS4cWZcVak54kXl6gI2iKw9N8U	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P53051	uniprotkb:P38646	intact:EBI-10464|ensemblfungi:YGR287C|uniprotkb:Q76CZ0|uniprotkb:D6VV64	intact:EBI-354932|ensembl:ENSP00000297185|uniprotkb:P30036|uniprotkb:P31932|uniprotkb:Q6GU03|uniprotkb:Q9BWB7|uniprotkb:B2RCM1|uniprotkb:Q1HB43|uniprotkb:Q53H23|uniprotkb:Q9UC56	psi-mi:malx3_yeast(display_long)|uniprotkb:YGR287C(locus name)|uniprotkb:IMA1(gene name)|psi-mi:IMA1(display_short)|uniprotkb:Alpha-glucosidase(gene name synonym)|uniprotkb:Isomaltase 1(gene name synonym)	psi-mi:grp75_human(display_long)|uniprotkb:HSPA9(gene name)|psi-mi:HSPA9(display_short)|uniprotkb:GRP75(gene name synonym)|uniprotkb:HSPA9B(gene name synonym)|uniprotkb:75 kDa glucose-regulated protein(gene name synonym)|uniprotkb:Heat shock 70 kDa protein 9(gene name synonym)|uniprotkb:Peptide-binding protein 74(gene name synonym)|uniprotkb:Mortalin(gene name synonym)|uniprotkb:mt-HSP70(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11543508|imex:IM-24995-2231	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003519|interpro:IPR006047(Glycosyl hydrolase, family 13, catalytic region)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|rcsb pdb:3A47|rcsb pdb:3A4A|rcsb pdb:3AJ7|ensemblfungi:YGR287C(gene)|ensemblfungi:YGR287C_mRNA(transcript)|go:"GO:0000025"(maltose catabolic process)|go:"GO:0004556"(alpha-amylase activity)|go:"GO:0004574"(oligo-1,6-glucosidase activity)|go:"GO:0004575"(sucrose alpha-glucosidase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005987"(sucrose catabolic process)|go:"GO:0009313"(oligosaccharide catabolic process)|go:"GO:0032450"(maltose alpha-glucosidase activity)|go:"GO:0033934"(glucan 1,4-alpha-maltotriohydrolase activity)|go:"GO:0046352"(disaccharide catabolic process)|rcsb pdb:3AXH|rcsb pdb:3AXI|refseq:NP_011803.3|interpro:IPR013780(Glycosyl hydrolase, family 13, all-beta)|reactome:R-SCE-352230|sgd:YGR287C(identity)	reactome:R-HSA-8949613|reactome:R-HSA-8950505|ensembl:ENSG00000113013(gene)|ensembl:ENST00000297185(transcript)|go:"GO:0001401"(SAM complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005925"(focal adhesion)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0007007"(inner mitochondrial membrane organization)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045646"(regulation of erythrocyte differentiation)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0140275"(MIB complex)|go:"GO:1902037"(negative regulation of hematopoietic stem cell differentiation)|go:"GO:1903707"(negative regulation of hemopoiesis)|interpro:IPR012725(Chaperone DnaK)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|go:"GO:0070062"(extracellular exosome)|interpro:IPR043129|mint:P38646|rcsb pdb:3N8E|rcsb pdb:4KBO|rcsb pdb:6NHK|rcsb pdb:6P2U|rcsb pdb:6PMT|reactome:R-HSA-1268020|reactome:R-HSA-3371453|refseq:NP_004125.3|dip:DIP-32936N|entrezgene/locuslink:3313(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:FhUpCS+n2c22jDt6Ai5m93wM3/w559292	rogid:xjSHeTKBb/lH1XNEEiMIjsM+XcE9606	intact-crc:C40F26DE07E36658|rigid:Dkd2c8EWAskYKCAFjynK6eERRZM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UJV3-2	uniprotkb:P53038	intact:EBI-10172526|ensembl:ENSP00000413976	intact:EBI-19106|uniprotkb:D6VUN1|ensemblfungi:YGR099W	psi-mi:q9ujv3-2(display_long)|uniprotkb:RING-type E3 ubiquitin transferase MID2(gene name synonym)|uniprotkb:FXY2(gene name synonym)|uniprotkb:Midin-2(gene name synonym)|uniprotkb:Midline defect 2(gene name synonym)|uniprotkb:Midline-2(gene name synonym)|uniprotkb:RING finger protein 60(gene name synonym)|uniprotkb:RNF60(gene name synonym)|uniprotkb:TRIM1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 1(gene name synonym)|uniprotkb:MID2(gene name)|psi-mi:MID2(display_short)	psi-mi:tel2_yeast(display_long)|uniprotkb:YGR099W(locus name)|uniprotkb:TEL2(gene name)|psi-mi:TEL2(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11543497|imex:IM-24995-2230	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-751983(isoform-parent)|uniprotkb:Q9UJV3-2(isoform-parent)|ensembl:ENSG00000080561(gene)|ensembl:ENST00000443968(transcript)|entrezgene/locuslink:11043(identity)	sgd:S000003331|ensemblfungi:YGR099W(gene)|ensemblfungi:YGR099W_mRNA(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0005829"(cytosol)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0034502"(protein localization to chromosome)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0070209"(ASTRA complex)|interpro:IPR019337|interpro:IPR038528|rcsb pdb:3O4Z|refseq:NP_011613.3|dip:DIP-1245N|mint:P53038|sgd:YGR099W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:/FJ+V2H7SaWon7caUWkEkmHFVxQ9606	rogid:SZibPBili0M8YgHIwxf+sKkLk+M559292	intact-crc:248BCCB043ABB73C|rigid:six8sufYSUVN6LDhYbISxep+gaM	false	sufficient binding region:21-705	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8IYA8	uniprotkb:P53038	intact:EBI-8638439|intact:EBI-28969497|ensembl:ENSP00000296449|ensembl:ENSP00000391788|ensembl:ENSP00000407837|uniprotkb:C9JJL0|uniprotkb:Q96LP7|intact:MINT-8162095|uniprotkb:Q05DG9	intact:EBI-19106|uniprotkb:D6VUN1|ensemblfungi:YGR099W	psi-mi:iho1_human(display_long)|uniprotkb:IHO1(gene name)|psi-mi:IHO1(display_short)|uniprotkb:CCDC36(gene name synonym)|uniprotkb:Cancer/testis antigen 74(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 36(gene name synonym)	psi-mi:tel2_yeast(display_long)|uniprotkb:YGR099W(locus name)|uniprotkb:TEL2(gene name)|psi-mi:TEL2(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11543486|imex:IM-24995-2229	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000296449|ensembl:ENST00000366429|ensembl:ENSP00000403700|ensembl:ENSP00000391788|ensembl:ENSP00000407837|ensembl:ENSG00000173421(gene)|ensembl:ENST00000296449(transcript)|ensembl:ENST00000438782(transcript)|ensembl:ENST00000452691(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0006310"(DNA recombination)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0042138"(meiotic DNA double-strand break formation)|go:"GO:0048477"(oogenesis)|go:"GO:0060629"(regulation of homologous chromosome segregation)|interpro:IPR031529|mint:Q8IYA8|refseq:XP_011531974.1|refseq:XP_011531975.1|refseq:NP_001128669.1|refseq:NP_835467.2|refseq:XP_006713187.1|entrezgene/locuslink:339834(identity)	sgd:S000003331|ensemblfungi:YGR099W(gene)|ensemblfungi:YGR099W_mRNA(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0005829"(cytosol)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0034502"(protein localization to chromosome)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0070209"(ASTRA complex)|interpro:IPR019337|interpro:IPR038528|rcsb pdb:3O4Z|refseq:NP_011613.3|dip:DIP-1245N|mint:P53038|sgd:YGR099W(identity)	-	comment:mint	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:+TNQLExkhmC1NWqsE240Cx7zFVU9606	rogid:SZibPBili0M8YgHIwxf+sKkLk+M559292	intact-crc:C73550DF0CEBBD53|rigid:XUwRPk82ZxXogZH7flupK9k8kbk	false	sufficient binding region:11-594	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P53174	uniprotkb:P63279	intact:EBI-6200|uniprotkb:D6VU88|ensemblfungi:YGL053W	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	psi-mi:prm8_yeast(display_long)|uniprotkb:PRM8(gene name)|psi-mi:PRM8(display_short)|uniprotkb:DUP1(gene name synonym)|uniprotkb:DUP240 protein PRM8(gene name synonym)|uniprotkb:Protein DUP1(gene name synonym)|uniprotkb:YGL053W(locus name)	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11543584|imex:IM-24995-2239	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003021|refseq:NP_011462.1|dip:DIP-4067N|ensemblfungi:YGL053W(gene)|ensemblfungi:YGL053W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016192"(vesicle-mediated transport)|interpro:IPR001142(Yeast membrane protein DUP)|sgd:YGL053W(identity)	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N|entrezgene/locuslink:7329(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:rE9bUEB99azFFpZn5BA9/+Fhws8559292	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	intact-crc:2F46EBCDC6182050|rigid:CV9iIx2ViQs/XU2hxbBckXZun4s	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96BA8	uniprotkb:P53173	intact:EBI-6942903|ensembl:ENSP00000481956|intact:MINT-268046|intact:MINT-8162577|uniprotkb:Q8N2D5|uniprotkb:Q96CP0	intact:EBI-6633|uniprotkb:D6VU87|ensemblfungi:YGL054C	psi-mi:cr3l1_human(display_long)|uniprotkb:CREB3L1(gene name)|psi-mi:CREB3L1(display_short)|uniprotkb:OASIS(gene name synonym)|uniprotkb:PSEC0238(orf name)|uniprotkb:Old astrocyte specifically-induced substance(gene name synonym)	psi-mi:erv14_yeast(display_long)|uniprotkb:ERV14(gene name)|psi-mi:ERV14(display_short)|uniprotkb:YGL054C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11543575|imex:IM-24995-2238	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157613(gene)|ensembl:ENST00000621158(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0070278"(extracellular matrix constituent secretion)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029805|mint:Q96BA8|reactome:R-HSA-8874211|refseq:NP_443086.1|entrezgene/locuslink:90993(identity)	refseq:NP_011461.1|sgd:S000003022|dip:DIP-5457N|ensemblfungi:YGL054C(gene)|ensemblfungi:YGL054C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007120"(axial cellular bud site selection)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0030437"(ascospore formation)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0071944"(cell periphery)|go:"GO:1902684"(negative regulation of receptor localization to synapse)|go:"GO:2000311"(regulation of AMPA receptor activity)|interpro:IPR003377(Cornichon)|interpro:IPR033466|sgd:YGL054C(identity)	-	comment:mint|function:"Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE"	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:sMWUFmBeBBCO+T0Y2CuB/un1lBg9606	rogid:KxwdOCXkpx+NMjtv4y+kU2ID99M559292	intact-crc:32A520D5CFFAC3E4|rigid:U6rII9M7DePFPuypuFYYswtZoiM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P53142	uniprotkb:Q8N6L0	intact:EBI-23899|uniprotkb:D6VU42|ensemblfungi:YGL104C	intact:EBI-749265|uniprotkb:Q96MC3|ensembl:ENSP00000404220	psi-mi:vps73_yeast(display_long)|uniprotkb:VPS73(gene name)|psi-mi:VPS73(display_short)|uniprotkb:G3090(orf name)|uniprotkb:YGL104C(locus name)	psi-mi:kash5_human(display_long)|uniprotkb:KASH5(gene name)|psi-mi:KASH5(display_short)|uniprotkb:CCDC155(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 155(gene name synonym)|uniprotkb:KASH domain-containing protein 5(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11543566|imex:IM-24995-2237	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003072|refseq:NP_011411.3|reactome:R-SCE-5653890|dip:DIP-1727N|reactome:R-SCE-189200|reactome:R-SCE-196836|reactome:R-SCE-422356|reactome:R-SCE-6798695|reactome:R-SCE-8981373|ensemblfungi:YGL104C(gene)|ensemblfungi:YGL104C_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005739"(mitochondrion)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0055085"(transmembrane transport)|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR020846|interpro:IPR036259|sgd:YGL104C(identity)	refseq:NP_653289.3|ensembl:ENSG00000161609(gene)|ensembl:ENST00000447857(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034397"(telomere localization)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051225"(spindle assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0090172"(microtubule cytoskeleton organization involved in homologous chromosome segregation)|go:"GO:0090220"(chromosome localization to nuclear envelope involved in homologous chromosome segregation)|go:"GO:0090619"(meiotic spindle pole)|interpro:IPR011992(EF-Hand type)|interpro:IPR028168|interpro:IPR028170|interpro:IPR039508|mint:Q8N6L0|rcsb pdb:6R2I|rcsb pdb:6WMF|entrezgene/locuslink:147872(identity)	-	crc64:D924D9112516450D	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:zkQIzKo7WxqNdwmETnOcsziImGk559292	rogid:Wl9L7AcvDHCZuKjYLn8QgGIbZTc9606	intact-crc:AA50C48BB29139A0|rigid:g0C5VCuajHxAAuy2R40a/94nheI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9H0B3-3	uniprotkb:P53141	intact:EBI-11533070	intact:EBI-10988|ensemblfungi:YGL106W|uniprotkb:D6VU40	psi-mi:q9h0b3-3(display_long)|uniprotkb:IQCN(gene name)|psi-mi:IQCN(display_short)|uniprotkb:KIAA1683(gene name synonym)	psi-mi:mlc1_yeast(display_long)|uniprotkb:G3080(orf name)|uniprotkb:MLC1(gene name)|psi-mi:MLC1(display_short)|uniprotkb:YGL106W(locus name)|uniprotkb:Myosin-2 light chain(gene name synonym)|uniprotkb:Calmodulin-like myosin light chain MLC1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11543557|imex:IM-24995-2236	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-745878(isoform-parent)|entrezgene/locuslink:80726(identity)	ensemblfungi:YGL106W(gene)|ensemblfungi:YGL106W_mRNA(transcript)|go:"GO:0000142"(cellular bud neck contractile ring)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005934"(cellular bud tip)|go:"GO:0006903"(vesicle targeting)|go:"GO:0016460"(myosin II complex)|go:"GO:0030427"(site of polarized growth)|go:"GO:0031489"(myosin V binding)|go:"GO:0031982"(vesicle)|go:"GO:0032038"(myosin II heavy chain binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0120155"(MIH complex)|go:"GO:1903476"(protein localization to cell division site involved in mitotic actomyosin contractile ring assembly)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|rcsb pdb:1M45|rcsb pdb:1M46|rcsb pdb:1N2D|rcsb pdb:2FCD|rcsb pdb:2FCE|reactome:R-SCE-5627123|go:"GO:0005935"(cellular bud neck)|refseq:NP_011409.1|sgd:S000003074|mint:P53141|dip:DIP-5576N|sgd:YGL106W(identity)	-	-	crc64:D7508123C101E4A6	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:oC4OG+AsWyQjmj2DKSPcLkrGYb89606	rogid:eC7nuA9RcHvmBgTFHG73tBQWfIY559292	intact-crc:8D470E870EF67AC4|rigid:jOXjZZKV7oegFRCcMw2x0MI7Ig8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P53140	uniprotkb:P43355	intact:EBI-23904|uniprotkb:Q66RA9|uniprotkb:D6VU39|ensemblfungi:YGL107C	intact:EBI-740978|ensembl:ENSP00000349085|uniprotkb:O00346|uniprotkb:B2RC81	psi-mi:rmd9_yeast(display_long)|uniprotkb:YGL107C(locus name)|uniprotkb:G3075(orf name)|uniprotkb:RMD9(gene name)|psi-mi:RMD9(display_short)|uniprotkb:Required for meiotic nuclear division protein 9(gene name synonym)	psi-mi:maga1_human(display_long)|uniprotkb:MAGE-1 antigen(gene name synonym)|uniprotkb:Antigen MZ2-E(gene name synonym)|uniprotkb:Cancer/testis antigen 1.1(gene name synonym)|uniprotkb:MAGEA1(gene name)|psi-mi:MAGEA1(display_short)|uniprotkb:MAGE1(gene name synonym)|uniprotkb:MAGE1A(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11543548|imex:IM-24995-2235	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003075|refseq:NP_011408.1|interpro:IPR011990(Tetratricopeptide-like helical)|ensemblfungi:YGL107C(gene)|ensemblfungi:YGL107C_mRNA(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006413"(translational initiation)|go:"GO:0009060"(aerobic respiration)|go:"GO:0030435"(sporulation resulting in formation of a cellular spore)|go:"GO:0031314"(extrinsic component of mitochondrial inner membrane)|go:"GO:0043488"(regulation of mRNA stability)|rcsb pdb:7A9W|rcsb pdb:7A9X|sgd:YGL107C(identity)	refseq:NP_004979.3|ensembl:ENSG00000198681(gene)|ensembl:ENST00000356661(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|interpro:IPR002190(MAGE protein)|interpro:IPR021072|interpro:IPR030093|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|rcsb pdb:1W72|rcsb pdb:3BO8|dip:DIP-54794N|entrezgene/locuslink:4100(identity)	-	-	crc64:544EEB1F9F4E9D33	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:iO06ej1OrtaTNHBwQQFnMVZ1r1g559292	rogid:6XW3mnTNM3yvOtXmiFbU8Uz3hjA9606	intact-crc:B43925F6026622CB|rigid:5UBKUn8pyW5c8uX9ViH3Y8IOGZQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P53129	uniprotkb:Q9Y2J4	intact:EBI-23945|uniprotkb:D6VU24|ensemblfungi:YGL124C	intact:EBI-746752|intact:EBI-28986657|ensembl:ENSP00000409999|uniprotkb:Q53EP1|uniprotkb:Q96F99|uniprotkb:Q9UKB4|uniprotkb:A8K6F1|uniprotkb:B7Z5Q1|uniprotkb:E9PHW3	psi-mi:mon1_yeast(display_long)|uniprotkb:YGL124C(locus name)|uniprotkb:G2889(orf name)|uniprotkb:MON1(gene name)|psi-mi:MON1(display_short)|uniprotkb:AUT12(gene name synonym)|uniprotkb:Monensin sensitivity protein 1(gene name synonym)|uniprotkb:Autophagy-related protein 12(gene name synonym)	psi-mi:amol2_human(display_long)|uniprotkb:Leman coiled-coil protein(gene name synonym)|uniprotkb:AMOTL2(gene name)|psi-mi:AMOTL2(display_short)|uniprotkb:KIAA0989(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11543537|imex:IM-24995-2234	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011391.2|sgd:S000003092|dip:DIP-5483N|mint:P53129|ensemblfungi:YGL124C(gene)|ensemblfungi:YGL124C_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006914"(autophagy)|go:"GO:0010314"(phosphatidylinositol-5-phosphate binding)|go:"GO:0016236"(macroautophagy)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0032585"(multivesicular body membrane)|go:"GO:0035658"(Mon1-Ccz1 complex)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044395"(protein targeting to vacuolar membrane)|go:"GO:0048278"(vesicle docking)|interpro:IPR004353(Protein of unknown function DUF254, SAND)|interpro:IPR043970|interpro:IPR043971|interpro:IPR043972|reactome:R-SCE-8876198|sgd:YGL124C(identity)	refseq:NP_001265612.1|refseq:NP_001265614.1|ensembl:ENSG00000114019(gene)|refseq:XP_006713717.1|refseq:NP_057285.3|refseq:XP_011511183.1|ensembl:ENST00000422605(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0003365"(establishment of cell polarity involved in ameboidal cell migration)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0035329"(hippo signaling)|go:"GO:0055037"(recycling endosome)|interpro:IPR009114(Angiomotin)|interpro:IPR024646|mint:Q9Y2J4|reactome:R-HSA-2028269|refseq:XP_016862069.1|refseq:XP_016862070.1|refseq:XP_016862071.1|ensembl:ENST00000249883|ensembl:ENSP00000249883|ensembl:ENSP00000409999|ensembl:ENST00000513145|ensembl:ENSP00000425475|ensembl:ENST00000514516|ensembl:ENSP00000424765|dip:DIP-57510N|entrezgene/locuslink:51421(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:9tNVB/LFcvinM/mEzRj6ezSNCWo559292	rogid:SHtKAcLLnTpSSLwVE7yQ1WECoZk9606	intact-crc:225C83D0771D81B0|rigid:4ZMhJLKK2G42jq8MacT3eZcTpvs	false	-	sufficient binding region:314-779	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P53176	uniprotkb:P63279	intact:EBI-6205|uniprotkb:D6VU89|ensemblfungi:YGL051W	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	psi-mi:mst27_yeast(display_long)|uniprotkb:MST27(gene name)|psi-mi:MST27(display_short)|uniprotkb:DUP2(gene name synonym)|uniprotkb:DUP240 protein MST27(gene name synonym)|uniprotkb:YGL051W(locus name)	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11543593|imex:IM-24995-2240	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003019|refseq:NP_011464.1|dip:DIP-1852N|ensemblfungi:YGL051W(gene)|ensemblfungi:YGL051W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030663"(COPI-coated vesicle membrane)|interpro:IPR001142(Yeast membrane protein DUP)|sgd:YGL051W(identity)	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N|entrezgene/locuslink:7329(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Vt2rgCK0Q+Ia3/1xU5hD7i+OCvg559292	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	intact-crc:CE205951699B10D2|rigid:EDMg/R5oMoO1sTMuoldYSwH7pR4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9Y371	uniprotkb:P53218	intact:EBI-2623095|uniprotkb:Q9H3Z0|uniprotkb:Q9NYA9|uniprotkb:Q9NR47|uniprotkb:Q5H8U5|ensembl:ENSP00000473267|uniprotkb:B4E182	intact:EBI-13662|uniprotkb:D6VUG5|ensemblfungi:YGR030C	psi-mi:shlb1_human(display_long)|uniprotkb:KIAA0491(gene name synonym)|uniprotkb:Bax-interacting factor 1(gene name synonym)|uniprotkb:SH3 domain-containing GRB2-like protein B1(gene name synonym)|uniprotkb:CGI-61(orf name)|uniprotkb:SH3GLB1(gene name)|psi-mi:SH3GLB1(display_short)	psi-mi:pop6_yeast(display_long)|uniprotkb:POP6(gene name)|psi-mi:POP6(display_short)|uniprotkb:RNA-processing protein POP6(gene name synonym)|uniprotkb:RNases P/MRP 18.2 kDa subunit(gene name synonym)|uniprotkb:YGR030C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11543647|imex:IM-24995-2246	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001193580.1|refseq:NP_001193581.1|refseq:NP_057093.1|go:"GO:0030496"(midbody)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032801"(receptor catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0048102"(autophagic cell death)|go:"GO:0090148"(membrane fission)|go:"GO:1903527"(positive regulation of membrane tubulation)|go:"GO:1903778"(protein localization to vacuolar membrane)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|go:"GO:2000786"(positive regulation of autophagosome assembly)|interpro:IPR001452(Src homology-3)|interpro:IPR004148(BAR)|interpro:IPR027267|interpro:IPR028503|interpro:IPR035695|interpro:IPR036028|mint:Q9Y371|rcsb pdb:6UP6|rcsb pdb:6UPN|ensembl:ENSG00000097033(gene)|ensembl:ENST00000370558(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0006915"(apoptotic process)|go:"GO:0008289"(lipid binding)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016241"(regulation of macroautophagy)|refseq:NP_001193582.1|dip:DIP-41970N|entrezgene/locuslink:51100(identity)	refseq:NP_011544.1|sgd:S000003262|ensemblfungi:YGR030C(gene)|ensemblfungi:YGR030C_mRNA(transcript)|go:"GO:0000172"(ribonuclease MRP complex)|go:"GO:0000294"(nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay)|go:"GO:0003723"(RNA binding)|go:"GO:0004526"(ribonuclease P activity)|go:"GO:0005634"(nucleus)|go:"GO:0005655"(nucleolar ribonuclease P complex)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0008033"(tRNA processing)|go:"GO:0034965"(intronic box C/D RNA processing)|go:"GO:0042134"(rRNA primary transcript binding)|interpro:IPR002775(Alba, DNA/RNA-binding protein)|rcsb pdb:3IAB|rcsb pdb:6AGB|rcsb pdb:6AH3|rcsb pdb:6W6V|rcsb pdb:7C79|rcsb pdb:7C7A|mint:P53218|dip:DIP-6775N|sgd:YGR030C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:HSs455W45ciZL56fJSPOIvfhUIw9606	rogid:ynYc14nNfgwjbvWl8qgK5nKGOOo559292	intact-crc:0D9EE2E09961F0CE|rigid:eV2qszuzE22qQIQPSb168a36WRY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q969K4	uniprotkb:P53212	intact:EBI-7223971|uniprotkb:Q71MF1|uniprotkb:D3DNB0|intact:MINT-1193021|uniprotkb:Q6ZNU9|uniprotkb:Q96S63|uniprotkb:Q96S62|ensembl:ENSP00000232744	intact:EBI-23099|uniprotkb:D6VUF6|ensemblfungi:YGR021W	psi-mi:abtb1_human(display_long)|uniprotkb:ABTB1(gene name)|psi-mi:ABTB1(display_short)|uniprotkb:Elongation factor 1A-binding protein(gene name synonym)|uniprotkb:BPOZ(gene name synonym)|uniprotkb:PP2259(orf name)	psi-mi:yg1d_yeast(display_long)|uniprotkb:YGR021W(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11543638|imex:IM-24995-2245	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011511515.1|refseq:NP_115937.1|refseq:NP_742024.1|ensembl:ENSG00000114626(gene)|ensembl:ENST00000232744(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR020683|interpro:IPR036770|interpro:IPR044515|refseq:XP_016862776.1|entrezgene/locuslink:80325(identity)	refseq:NP_011535.1|sgd:S000003253|dip:DIP-6261N|mint:P53212|ensemblfungi:YGR021W(gene)|ensemblfungi:YGR021W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|interpro:IPR002876(Protein of unknown function DUF28)|interpro:IPR017856(Integrase, N-terminal zinc-binding domain-like)|interpro:IPR026564|interpro:IPR029072|sgd:YGR021W(identity)	-	comment:mint|comment:homomint|function:May act as a mediator of the PTEN growth-suppressive signaling pathway. May play a role in developmental processes	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:uWEJ/hAJBiKef/EJSNxP4OsXloM9606	rogid:/lU8xaIM/O6RTUPSlVUuReKFU5E559292	intact-crc:9A3DA9C069AF1253|rigid:Wf1QdDYuUkCLAMcjXza8p6ERQG4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P53202	uniprotkb:Q9H898-2	intact:EBI-23065|uniprotkb:D6VUE0|ensemblfungi:YGR003W	intact:EBI-11529334|ensembl:ENSP00000319785	psi-mi:cul3_yeast(display_long)|uniprotkb:CUL3(gene name)|psi-mi:CUL3(display_short)|uniprotkb:Cullin-B(gene name synonym)|uniprotkb:YGR003W(locus name)	psi-mi:q9h898-2(display_long)|uniprotkb:ZMAT4(gene name)|psi-mi:ZMAT4(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11543629|imex:IM-24995-2244	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011517.1|sgd:S000003235|dip:DIP-5506N|mint:P53202|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|ensemblfungi:YGR003W(gene)|ensemblfungi:YGR003W_mRNA(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|sgd:YGR003W(identity)	ensembl:ENSG00000165061(gene)|ensembl:ENST00000315769(transcript)|intact:EBI-2548542(isoform-parent)|uniprotkb:Q9H898-2(isoform-parent)|entrezgene/locuslink:79698(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:FvYjEpmLA9mF35UTi97nLZwp0eE559292	rogid:LOS8TGoD/X97NtzSXSQ3uppdS6s9606	intact-crc:B16C32F667CDF389|rigid:vDYwV4mPVgbNuC6HBYVnBl6io+E	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P53202	uniprotkb:Q96IK5	intact:EBI-23065|uniprotkb:D6VUE0|ensemblfungi:YGR003W	intact:EBI-2548508|ensembl:ENSP00000282570|uniprotkb:Q9H826|uniprotkb:Q9H8V7|uniprotkb:Q9H927	psi-mi:cul3_yeast(display_long)|uniprotkb:CUL3(gene name)|psi-mi:CUL3(display_short)|uniprotkb:Cullin-B(gene name synonym)|uniprotkb:YGR003W(locus name)	psi-mi:gmcl1_human(display_long)|uniprotkb:GMCL1(gene name)|psi-mi:GMCL1(display_short)|uniprotkb:GCL(gene name synonym)|uniprotkb:BTBD13(gene name synonym)|uniprotkb:SPATA29(gene name synonym)|uniprotkb:Spermatogenesis-associated protein 29(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11543620|imex:IM-24995-2243	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011517.1|sgd:S000003235|dip:DIP-5506N|mint:P53202|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|ensemblfungi:YGR003W(gene)|ensemblfungi:YGR003W_mRNA(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|sgd:YGR003W(identity)	ensembl:ENSG00000087338(gene)|ensembl:ENST00000282570(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0007281"(germ cell development)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016363"(nuclear matrix)|go:"GO:0042802"(identical protein binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR043380|refseq:NP_848526.1|entrezgene/locuslink:64395(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:FvYjEpmLA9mF35UTi97nLZwp0eE559292	rogid:ED8yqySVu7BWxpw3DUSNBZSQWrk9606	intact-crc:E26DC6C390914FFF|rigid:kjnuALvK/s4J4YRNLcNbpMJrLbA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P53202	uniprotkb:O95198	intact:EBI-23065|uniprotkb:D6VUE0|ensemblfungi:YGR003W	intact:EBI-746999|uniprotkb:B2RD18|uniprotkb:Q8N484|uniprotkb:Q8TBH5|uniprotkb:A6NCM7|uniprotkb:B4DFH7|uniprotkb:F5H6M3|ensembl:ENSP00000226725	psi-mi:cul3_yeast(display_long)|uniprotkb:CUL3(gene name)|psi-mi:CUL3(display_short)|uniprotkb:Cullin-B(gene name synonym)|uniprotkb:YGR003W(locus name)	psi-mi:klhl2_human(display_long)|uniprotkb:Actin-binding protein Mayven(gene name synonym)|uniprotkb:KLHL2(gene name)|psi-mi:KLHL2(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11543611|imex:IM-24995-2242	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011517.1|sgd:S000003235|dip:DIP-5506N|mint:P53202|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|ensemblfungi:YGR003W(gene)|ensemblfungi:YGR003W_mRNA(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|sgd:YGR003W(identity)	refseq:NP_001154993.1|refseq:NP_001154994.1|refseq:NP_009177.3|refseq:NP_001317952.1|refseq:NP_001317953.1|refseq:XP_016863165.1|ensembl:ENSG00000109466(gene)|ensembl:ENST00000226725(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030027"(lamellipodium)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR017096(Kelch-like protein, gigaxonin)|interpro:IPR044072|mint:O95198|rcsb pdb:2XN4|rcsb pdb:4CHB|reactome:R-HSA-8951664|reactome:R-HSA-983168|go:"GO:0042802"(identical protein binding)|entrezgene/locuslink:11275(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:FvYjEpmLA9mF35UTi97nLZwp0eE559292	rogid:tFegR2lJZccRqs4qUjdT3PNjNnk9606	intact-crc:828F955A3F902753|rigid:4KFd6cGaEu7kzWvz7zzXloqu8ak	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O43791	uniprotkb:P53202	intact:EBI-743549|uniprotkb:Q53HJ1|uniprotkb:B2R6S3|uniprotkb:D3DTW7|ensembl:ENSP00000240327|ensembl:ENSP00000377001|ensembl:ENSP00000420908|ensembl:ENSP00000424119|ensembl:ENSP00000425905|ensembl:ENSP00000426986|ensembl:ENSP00000499562	intact:EBI-23065|uniprotkb:D6VUE0|ensemblfungi:YGR003W	psi-mi:spop_human(display_long)|uniprotkb:HIB homolog 1(gene name synonym)|uniprotkb:Roadkill homolog 1(gene name synonym)|uniprotkb:SPOP(gene name)|psi-mi:SPOP(display_short)	psi-mi:cul3_yeast(display_long)|uniprotkb:CUL3(gene name)|psi-mi:CUL3(display_short)|uniprotkb:Cullin-B(gene name synonym)|uniprotkb:YGR003W(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11543602|imex:IM-24995-2241	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001007227.1|refseq:NP_001007228.1|refseq:NP_001007229.1|refseq:NP_001007230.1|refseq:NP_001007231.1|refseq:NP_003554.1|refseq:XP_005257780.1|refseq:XP_005257781.1|ensembl:ENSG00000121067(gene)|ensembl:ENST00000347630(transcript)|ensembl:ENST00000393328(transcript)|ensembl:ENST00000503676(transcript)|ensembl:ENST00000504102(transcript)|ensembl:ENST00000509079(transcript)|ensembl:ENST00000514121(transcript)|ensembl:ENST00000665825(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0016607"(nuclear speck)|go:"GO:0030162"(regulation of proteolysis)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR034089|mint:O43791|rcsb pdb:2CR2|rcsb pdb:3HQH|rcsb pdb:3HQI|rcsb pdb:3HQL|rcsb pdb:3HQM|rcsb pdb:3HSV|rcsb pdb:3HTM|rcsb pdb:3HU6|rcsb pdb:3IVB|rcsb pdb:3IVQ|rcsb pdb:3IVV|rcsb pdb:4EOZ|rcsb pdb:4HS2|rcsb pdb:4J8Z|rcsb pdb:4O1V|rcsb pdb:6F8F|rcsb pdb:6F8G|rcsb pdb:6I41|rcsb pdb:6I5P|rcsb pdb:6I68|rcsb pdb:6I7A|rcsb pdb:7D3D|rcsb pdb:7LIN|rcsb pdb:7LIO|rcsb pdb:7LIP|rcsb pdb:7LIQ|reactome:R-HSA-5632684|go:"GO:0005634"(nucleus)|refseq:XP_016880693.1|dip:DIP-50517N|entrezgene/locuslink:8405(identity)	refseq:NP_011517.1|sgd:S000003235|dip:DIP-5506N|mint:P53202|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|ensemblfungi:YGR003W(gene)|ensemblfungi:YGR003W_mRNA(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|sgd:YGR003W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:PC9ofpvk14xwTnnqT590/YRnx/49606	rogid:FvYjEpmLA9mF35UTi97nLZwp0eE559292	intact-crc:6947FA9BF91BD2F3|rigid:zQaCFGgNUtTlFHC9ppqESiQzvUs	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P53243	uniprotkb:Q96S82	intact:EBI-23197|uniprotkb:D6VUK1|ensemblfungi:YGR067C	intact:EBI-348604|uniprotkb:Q96I03|ensembl:ENSP00000378518|ensembl:ENSP00000454828|ensembl:ENSP00000457703|ensembl:ENSP00000457708|ensembl:ENSP00000500164|ensembl:ENSP00000500266|ensembl:ENSP00000500442|ensembl:ENSP00000500520|ensembl:ENSP00000500882|ensembl:ENSP00000354883|uniprotkb:D3DW57	psi-mi:yg2a_yeast(display_long)|uniprotkb:YGR067C(locus name)	psi-mi:ubl7_human(display_long)|uniprotkb:Ubiquitin-like protein SB132(gene name synonym)|uniprotkb:Bone marrow stromal cell ubiquitin-like protein(gene name synonym)|uniprotkb:UBL7(gene name)|psi-mi:UBL7(display_short)|uniprotkb:BMSCUBP(gene name synonym)|uniprotkb:SB132(orf name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11543680|imex:IM-24995-2249	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003299|refseq:NP_011581.4|dip:DIP-2819N|mint:P53243|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|ensemblfungi:YGR067C(gene)|ensemblfungi:YGR067C_mRNA(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|sgd:YGR067C(identity)	refseq:NP_116296.1|refseq:NP_957717.1|ensembl:ENST00000361351(transcript)|ensembl:ENST00000395081(transcript)|ensembl:ENST00000564488(transcript)|ensembl:ENST00000565335(transcript)|ensembl:ENST00000567435(transcript)|ensembl:ENST00000673054(transcript)|ensembl:ENST00000673073(transcript)|ensembl:ENST00000673120(transcript)|ensembl:ENST00000673153(transcript)|ensembl:ENST00000673461(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR029071|rcsb pdb:2CWB|rcsb pdb:2DEN|ensembl:ENSG00000138629(gene)|ensembl:ENSG00000288408(gene)|refseq:NP_001273668.1|refseq:NP_001273669.1|refseq:NP_001273670.1|refseq:NP_001273671.1|entrezgene/locuslink:84993(identity)	-	crc64:BB936C265B7B263F	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:/qkApijbHr7FKeeSJZ6IczHMf28559292	rogid:4E0ErEIkP/AQb+OHRuOd5wbXU/s9606	intact-crc:3AAC54F18B8B6431|rigid:S8zvAGQgBgIYqHUo1UXlwXsgxy8	false	sufficient binding region:1-794	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P53243	uniprotkb:Q8IUQ4-2	intact:EBI-23197|uniprotkb:D6VUK1|ensemblfungi:YGR067C	intact:EBI-11522811|ensembl:ENSP00000349156	psi-mi:yg2a_yeast(display_long)|uniprotkb:YGR067C(locus name)	psi-mi:q8iuq4-2(display_long)|uniprotkb:SIAH1(gene name)|psi-mi:SIAH1(display_short)|uniprotkb:HUMSIAH(gene name synonym)|uniprotkb:Seven in absentia homolog 1(gene name synonym)|uniprotkb:Siah-1a(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase SIAH1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11543667|imex:IM-24995-2248	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003299|refseq:NP_011581.4|dip:DIP-2819N|mint:P53243|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|ensemblfungi:YGR067C(gene)|ensemblfungi:YGR067C_mRNA(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|sgd:YGR067C(identity)	intact:EBI-747107(isoform-parent)|ensembl:ENSG00000196470(gene)|ensembl:ENST00000356721(transcript)|uniprotkb:Q8IUQ4-2(isoform-parent)|entrezgene/locuslink:6477(identity)	-	crc64:BB936C265B7B263F	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:/qkApijbHr7FKeeSJZ6IczHMf28559292	rogid:M4q06jVbWuq1mGMXvtuFBaMEgZM9606	intact-crc:B9F6431885556D15|rigid:trRKgSdgdVLhq8Xh70Mscr/zkUM	false	sufficient binding region:1-794	sufficient binding region:32-313	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P63279	uniprotkb:P53243	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	intact:EBI-23197|uniprotkb:D6VUK1|ensemblfungi:YGR067C	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:yg2a_yeast(display_long)|uniprotkb:YGR067C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11543656|imex:IM-24995-2247	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N|entrezgene/locuslink:7329(identity)	sgd:S000003299|refseq:NP_011581.4|dip:DIP-2819N|mint:P53243|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|ensemblfungi:YGR067C(gene)|ensemblfungi:YGR067C_mRNA(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|sgd:YGR067C(identity)	-	-	crc64:BB936C265B7B263F	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	rogid:/qkApijbHr7FKeeSJZ6IczHMf28559292	intact-crc:4BCBD9D14E7E0AE1|rigid:/jZIwuU3SbqWcHtgYxohgylsdM8	false	-	sufficient binding region:1-794	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:A0A0C4DGF1	uniprotkb:P53286	intact:EBI-10188476|ensembl:ENSP00000433657	intact:EBI-3796|uniprotkb:D6VUS2|ensemblfungi:YGR142W	psi-mi:a0a0c4dgf1_human(display_long)|uniprotkb:ZBTB32(gene name)|psi-mi:ZBTB32(display_short)	psi-mi:btn2_yeast(display_long)|uniprotkb:YGR142W(locus name)|uniprotkb:BTN2(gene name)|psi-mi:BTN2(display_short)|uniprotkb:Batten disease protein 2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11543745|imex:IM-24995-2256	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|ensembl:ENSG00000011590(gene)|ensembl:ENST00000481182(transcript)|go:"GO:0042802"(identical protein binding)|entrezgene/locuslink:27033(identity)	sgd:S000003374|refseq:NP_011658.3|dip:DIP-5534N|mint:P53286|ensemblfungi:YGR142W(gene)|ensemblfungi:YGR142W_mRNA(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005634"(nucleus)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006865"(amino acid transport)|go:"GO:0006885"(regulation of pH)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051087"(chaperone binding)|go:"GO:0140311"(protein sequestering activity)|sgd:YGR142W(identity)	-	-	crc64:E7AE1EB1E3612F3E	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:w3k7YT4kw/T+Xi5YBqGHSpHtwMM9606	rogid:Cu27xkwGMNyS4zLvUaG1UeH2mE0559292	intact-crc:13D4F01E348AD4DF|rigid:02tTGbPh1uOnYhZK9iXwT9tfYk4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P53286	uniprotkb:Q8N5R6	intact:EBI-3796|uniprotkb:D6VUS2|ensemblfungi:YGR142W	intact:EBI-740841|intact:EBI-953781|uniprotkb:B3KQ49|uniprotkb:A8K3U4|uniprotkb:A8MPQ6|uniprotkb:A8MV61|uniprotkb:A8MVU9|uniprotkb:Q9H5Q6|uniprotkb:Q8TAX6|intact:EBI-2320546|intact:EBI-11522976	psi-mi:btn2_yeast(display_long)|uniprotkb:YGR142W(locus name)|uniprotkb:BTN2(gene name)|psi-mi:BTN2(display_short)|uniprotkb:Batten disease protein 2(gene name synonym)	psi-mi:ccd33_human(display_long)|uniprotkb:CCDC33(gene name)|psi-mi:CCDC33(display_short)|uniprotkb:Cancer/testis antigen 61(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11543736|imex:IM-24995-2255	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003374|refseq:NP_011658.3|dip:DIP-5534N|mint:P53286|ensemblfungi:YGR142W(gene)|ensemblfungi:YGR142W_mRNA(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005634"(nucleus)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006865"(amino acid transport)|go:"GO:0006885"(regulation of pH)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051087"(chaperone binding)|go:"GO:0140311"(protein sequestering activity)|sgd:YGR142W(identity)	refseq:NP_079331.3|interpro:IPR000008(C2 calcium-dependent membrane targeting)|go:"GO:0005777"(peroxisome)|refseq:NP_001274110.1|refseq:NP_877592.2|mint:Q8N5R6|interpro:IPR035892|interpro:IPR039889|entrezgene/locuslink:80125(identity)	-	crc64:E7AE1EB1E3612F3E	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2021/11/30	rogid:Cu27xkwGMNyS4zLvUaG1UeH2mE0559292	rogid:eEIn7pQyfdHWx8TeLJpYy0i/gww9606	intact-crc:8A66950898D8F6AD|rigid:JS2g2RcnPmP5C7qNkAk1VjyMSKE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P61289	uniprotkb:P53278	intact:EBI-355546|uniprotkb:O35563|uniprotkb:P97373|uniprotkb:Q12920|uniprotkb:Q13172|uniprotkb:Q9BQD9|uniprotkb:A8K9A3|ensembl:ENSP00000466794	intact:EBI-23314|uniprotkb:D6VUR2|ensemblfungi:YGR130C	psi-mi:psme3_human(display_long)|uniprotkb:PSME3(gene name)|psi-mi:PSME3(display_short)|uniprotkb:Proteasome activator 28 subunit gamma(gene name synonym)|uniprotkb:Activator of multicatalytic protease subunit 3(gene name synonym)|uniprotkb:11S regulator complex subunit gamma(gene name synonym)|uniprotkb:Ki nuclear autoantigen(gene name synonym)	psi-mi:yg3a_yeast(display_long)|uniprotkb:YGR130C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11543727|imex:IM-24995-2254	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005780.2|refseq:NP_789839.1|ensembl:ENSG00000131467(gene)|ensembl:ENST00000590720(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0008537"(proteasome activator complex)|go:"GO:0010950"(positive regulation of endopeptidase activity)|go:"GO:0016020"(membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0061133"(endopeptidase activator activity)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0097371"(MDM2/MDM4 family protein binding)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR003185(Proteasome activator pa28, REG alpha subunit)|interpro:IPR003186(Proteasome activator pa28, REG beta subunit)|interpro:IPR009077(Proteasome activator pa28, REG alpha/beta subunit)|interpro:IPR036252|interpro:IPR036996|interpro:IPR036997|mint:P61289|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|entrezgene/locuslink:10197(identity)	refseq:NP_011646.1|sgd:S000003362|dip:DIP-3006N|mint:P53278|ensemblfungi:YGR130C(gene)|ensemblfungi:YGR130C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0032126"(eisosome)|sgd:YGR130C(identity)	-	-	crc64:D482327C9274C026	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:6EQY2Kj3Juf++m4eBDzPWMgbC2k9606	rogid:iTa1C3VXvI8QteEEgkfjQDp9gvY559292	intact-crc:CEAE1646611EC736|rigid:DC1j0vegFjPWtc6Trafxcf34fGE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O43791	uniprotkb:P53278	intact:EBI-743549|uniprotkb:Q53HJ1|uniprotkb:B2R6S3|uniprotkb:D3DTW7|ensembl:ENSP00000240327|ensembl:ENSP00000377001|ensembl:ENSP00000420908|ensembl:ENSP00000424119|ensembl:ENSP00000425905|ensembl:ENSP00000426986|ensembl:ENSP00000499562	intact:EBI-23314|uniprotkb:D6VUR2|ensemblfungi:YGR130C	psi-mi:spop_human(display_long)|uniprotkb:HIB homolog 1(gene name synonym)|uniprotkb:Roadkill homolog 1(gene name synonym)|uniprotkb:SPOP(gene name)|psi-mi:SPOP(display_short)	psi-mi:yg3a_yeast(display_long)|uniprotkb:YGR130C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11543718|imex:IM-24995-2253	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001007227.1|refseq:NP_001007228.1|refseq:NP_001007229.1|refseq:NP_001007230.1|refseq:NP_001007231.1|refseq:NP_003554.1|refseq:XP_005257780.1|refseq:XP_005257781.1|ensembl:ENSG00000121067(gene)|ensembl:ENST00000347630(transcript)|ensembl:ENST00000393328(transcript)|ensembl:ENST00000503676(transcript)|ensembl:ENST00000504102(transcript)|ensembl:ENST00000509079(transcript)|ensembl:ENST00000514121(transcript)|ensembl:ENST00000665825(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0016607"(nuclear speck)|go:"GO:0030162"(regulation of proteolysis)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR034089|mint:O43791|rcsb pdb:2CR2|rcsb pdb:3HQH|rcsb pdb:3HQI|rcsb pdb:3HQL|rcsb pdb:3HQM|rcsb pdb:3HSV|rcsb pdb:3HTM|rcsb pdb:3HU6|rcsb pdb:3IVB|rcsb pdb:3IVQ|rcsb pdb:3IVV|rcsb pdb:4EOZ|rcsb pdb:4HS2|rcsb pdb:4J8Z|rcsb pdb:4O1V|rcsb pdb:6F8F|rcsb pdb:6F8G|rcsb pdb:6I41|rcsb pdb:6I5P|rcsb pdb:6I68|rcsb pdb:6I7A|rcsb pdb:7D3D|rcsb pdb:7LIN|rcsb pdb:7LIO|rcsb pdb:7LIP|rcsb pdb:7LIQ|reactome:R-HSA-5632684|go:"GO:0005634"(nucleus)|refseq:XP_016880693.1|dip:DIP-50517N|entrezgene/locuslink:8405(identity)	refseq:NP_011646.1|sgd:S000003362|dip:DIP-3006N|mint:P53278|ensemblfungi:YGR130C(gene)|ensemblfungi:YGR130C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0032126"(eisosome)|sgd:YGR130C(identity)	-	-	crc64:D482327C9274C026	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:PC9ofpvk14xwTnnqT590/YRnx/49606	rogid:iTa1C3VXvI8QteEEgkfjQDp9gvY559292	intact-crc:69D14ECE217E15A4|rigid:XtueZT1ahsSmPIYF7JfJWCuO+cQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P53262	uniprotkb:Q969F0	intact:EBI-2061527|uniprotkb:D6VUN8|ensemblfungi:YGR106C	intact:EBI-743099|ensembl:ENSP00000359375	psi-mi:voa1_yeast(display_long)|uniprotkb:YGR106C(locus name)|uniprotkb:VOA1(gene name)|psi-mi:VOA1(display_short)	psi-mi:fate1_human(display_long)|uniprotkb:Tumor antigen BJ-HCC-2(gene name synonym)|uniprotkb:Cancer/testis antigen 43(gene name synonym)|uniprotkb:FATE1(gene name)|psi-mi:FATE1(display_short)|uniprotkb:FATE(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11543709|imex:IM-24995-2252	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003338|refseq:NP_011620.1|mint:P53262|ensemblfungi:YGR106C(gene)|ensemblfungi:YGR106C_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034622"|rcsb pdb:6C6L|rcsb pdb:6M0R|rcsb pdb:6M0S|rcsb pdb:6O7T|rcsb pdb:6O7U|rcsb pdb:6O7V|rcsb pdb:6O7W|rcsb pdb:6O7X|rcsb pdb:6PE4|rcsb pdb:6PE5|sgd:YGR106C(identity)	refseq:NP_149076.1|ensembl:ENSG00000147378(gene)|ensembl:ENST00000370350(transcript)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|go:"GO:0051562"(negative regulation of mitochondrial calcium ion concentration)|interpro:IPR039153|interpro:IPR039433|mint:Q969F0|entrezgene/locuslink:89885(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:lKLIonttSEX36IQaIKlzxS/Cdxg559292	rogid:Nm1N6lO92MHr5rIKC007oouF5RE9606	intact-crc:2E0262F3ED53BBFE|rigid:TrqFIPTlPqsUo/Q5JllfF0BXvLI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P53255	uniprotkb:Q2TAC2-2	intact:EBI-23234|uniprotkb:D6VUM5|ensemblfungi:YGR093W	intact:EBI-10961624|ensembl:ENSP00000376154	psi-mi:drn1_yeast(display_long)|uniprotkb:YGR093W(locus name)|uniprotkb:DRN1(gene name)|psi-mi:DRN1(display_short)|uniprotkb:Debranching enzyme-associated ribonuclease 1(gene name synonym)	psi-mi:q2tac2-2(display_long)|uniprotkb:CCDC57(gene name)|psi-mi:CCDC57(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11543700|imex:IM-24995-2251	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003325|interpro:IPR006768(Protein similar to CwfJ, C-terminal 1)|interpro:IPR006767(Protein similar to CwfJ, C-terminal 2)|refseq:NP_011607.3|mint:P53255|interpro:IPR040194|interpro:IPR036265|ensemblfungi:YGR093W(gene)|ensemblfungi:YGR093W_mRNA(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0061632"(RNA lariat debranching enzyme activator activity)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|sgd:YGR093W(identity)	ensembl:ENSG00000176155(gene)|ensembl:ENST00000392343(transcript)|uniprotkb:Q2TAC2-2(isoform-parent)|intact:EBI-2808286(isoform-parent)|entrezgene/locuslink:284001(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:oQ6T+SDSiEw5VpFLQvV/N6pRszs559292	rogid:RWcF0hgb1geIY959JUKrLK13Jx09606	intact-crc:6ED96581C66DEE5A|rigid:yQ2+o04bLwn6oSc0s6yweZVglRA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P63279	uniprotkb:P53252	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	intact:EBI-23225|uniprotkb:D6VUL8|ensemblfungi:YGR086C	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:pil1_yeast(display_long)|uniprotkb:YGR086C(locus name)|uniprotkb:PIL1(gene name)|psi-mi:PIL1(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11543691|imex:IM-24995-2250	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N|entrezgene/locuslink:7329(identity)	sgd:S000003318|refseq:NP_011600.3|dip:DIP-4618N|mint:P53252|ensemblfungi:YGR086C(gene)|ensemblfungi:YGR086C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0005886"(plasma membrane)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006897"(endocytosis)|go:"GO:0008104"(protein localization)|go:"GO:0008289"(lipid binding)|go:"GO:0009408"(response to heat)|go:"GO:0032126"(eisosome)|go:"GO:0036286"(eisosome filament)|go:"GO:0070941"(eisosome assembly)|go:"GO:0071944"(cell periphery)|go:"GO:0097446"(protein localization to eisosome filament)|interpro:IPR027267|interpro:IPR028245|sgd:YGR086C(identity)	-	-	crc64:C86AE5ABB508EA03	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	rogid:OtBCHiFwxzPwPX5y1oMTFqlc1Po559292	intact-crc:4959F1668636E8C7|rigid:8zEfk4Ahxs5xtk9FgPDZWRHYZBM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q5T124-6	uniprotkb:P53286	intact:EBI-11524408	intact:EBI-3796|uniprotkb:D6VUS2|ensemblfungi:YGR142W	psi-mi:q5t124-6(display_long)|uniprotkb:UBXN11(gene name)|psi-mi:UBXN11(display_short)|uniprotkb:Colorectal tumor-associated antigen COA-1(gene name synonym)|uniprotkb:SOC(gene name synonym)|uniprotkb:Socius(gene name synonym)|uniprotkb:UBX domain-containing protein 5(gene name synonym)|uniprotkb:UBXD5(gene name synonym)|uniprotkb:PP2243(orf name)	psi-mi:btn2_yeast(display_long)|uniprotkb:YGR142W(locus name)|uniprotkb:BTN2(gene name)|psi-mi:BTN2(display_short)|uniprotkb:Batten disease protein 2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11543792|imex:IM-24995-2261	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-746004(isoform-parent)|uniprotkb:Q5T124-6(isoform-parent)|entrezgene/locuslink:91544(identity)	sgd:S000003374|refseq:NP_011658.3|dip:DIP-5534N|mint:P53286|ensemblfungi:YGR142W(gene)|ensemblfungi:YGR142W_mRNA(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005634"(nucleus)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006865"(amino acid transport)|go:"GO:0006885"(regulation of pH)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051087"(chaperone binding)|go:"GO:0140311"(protein sequestering activity)|sgd:YGR142W(identity)	-	-	crc64:E7AE1EB1E3612F3E	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:1YSjG/p2ihcjl4P8KdPCaX2HxiY9606	rogid:Cu27xkwGMNyS4zLvUaG1UeH2mE0559292	intact-crc:5682D4B0AB0C37F7|rigid:ja8+IzdWLG0ECQqfwNmkJEO2qik	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P53286	uniprotkb:Q53G59	intact:EBI-3796|uniprotkb:D6VUS2|ensemblfungi:YGR142W	intact:EBI-740929|ensembl:ENSP00000356230|uniprotkb:A6NEN8|uniprotkb:B7Z7B8|uniprotkb:Q9HBX5	psi-mi:btn2_yeast(display_long)|uniprotkb:YGR142W(locus name)|uniprotkb:BTN2(gene name)|psi-mi:BTN2(display_short)|uniprotkb:Batten disease protein 2(gene name synonym)	psi-mi:klh12_human(display_long)|uniprotkb:CUL3-interacting protein 1(gene name synonym)|uniprotkb:KLHL12(gene name)|psi-mi:KLHL12(display_short)|uniprotkb:C3IP1(gene name synonym)|uniprotkb:DKIR homolog(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11543783|imex:IM-24995-2260	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003374|refseq:NP_011658.3|dip:DIP-5534N|mint:P53286|ensemblfungi:YGR142W(gene)|ensemblfungi:YGR142W_mRNA(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005634"(nucleus)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006865"(amino acid transport)|go:"GO:0006885"(regulation of pH)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051087"(chaperone binding)|go:"GO:0140311"(protein sequestering activity)|sgd:YGR142W(identity)	go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048208"(COPII vesicle coating)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR017096(Kelch-like protein, gigaxonin)|mint:Q53G59|rcsb pdb:2VPJ|rcsb pdb:6TTK|rcsb pdb:6V7O|reactome:R-HSA-4641258|refseq:NP_067646.1|ensembl:ENSG00000117153(gene)|ensembl:ENST00000367261(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0014029"(neural crest formation)|go:"GO:0014032"(neural crest cell development)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0034451"(centriolar satellite)|refseq:NP_001289980.1|refseq:NP_001290038.1|entrezgene/locuslink:59349(identity)	-	crc64:E7AE1EB1E3612F3E	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Cu27xkwGMNyS4zLvUaG1UeH2mE0559292	rogid:C4I/Ys9vqNqfG61HsXRZhywP4vE9606	intact-crc:B5D8F197DD80015E|rigid:r2ZpBzJpduxdwbAVvF/LFDNgKak	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q13164	uniprotkb:P53286	intact:EBI-1213983|uniprotkb:Q16634|uniprotkb:Q59F50|uniprotkb:Q6QLU7|uniprotkb:Q7L4P4|uniprotkb:Q969G1|uniprotkb:Q96G51|intact:EBI-28979986|ensembl:ENSP00000311005|ensembl:ENSP00000378966|ensembl:ENSP00000378968	intact:EBI-3796|uniprotkb:D6VUS2|ensemblfungi:YGR142W	psi-mi:mk07_human(display_long)|uniprotkb:MAPK7(gene name)|psi-mi:MAPK7(display_short)|uniprotkb:BMK1(gene name synonym)|uniprotkb:ERK5(gene name synonym)|uniprotkb:PRKM7(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 5(gene name synonym)|uniprotkb:Big MAP kinase 1(gene name synonym)	psi-mi:btn2_yeast(display_long)|uniprotkb:YGR142W(locus name)|uniprotkb:BTN2(gene name)|psi-mi:BTN2(display_short)|uniprotkb:Batten disease protein 2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11543772|imex:IM-24995-2259	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002740.2|refseq:NP_620601.1|refseq:NP_620602.2|refseq:NP_620603.2|ensembl:ENST00000299612|ensembl:ENSP00000299612|ensembl:ENSP00000311005|ensembl:ENSP00000378966|ensembl:ENSP00000378968|refseq:XP_011522259.1|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0036003"(positive regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0051019"(mitogen-activated protein kinase binding)|go:"GO:0051247"(positive regulation of protein metabolic process)|go:"GO:0051344"(negative regulation of cyclic-nucleotide phosphodiesterase activity)|go:"GO:0060761"(negative regulation of response to cytokine stimulus)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071499"(cellular response to laminar fluid shear stress)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1902176"(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:2000352"(negative regulation of endothelial cell apoptotic process)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q13164|rcsb pdb:2Q8Y|rcsb pdb:4B99|rcsb pdb:4IC7|rcsb pdb:4IC8|rcsb pdb:4ZSG|rcsb pdb:4ZSJ|rcsb pdb:4ZSL|rcsb pdb:5BYY|rcsb pdb:5BYZ|rcsb pdb:5O7I|rcsb pdb:6HKM|rcsb pdb:6HKN|reactome:R-HSA-198753|reactome:R-HSA-198765|reactome:R-HSA-202670|reactome:R-HSA-2559582|reactome:R-HSA-881907|reactome:R-HSA-8853659|ensembl:ENSG00000166484(gene)|ensembl:ENST00000308406(transcript)|ensembl:ENST00000395602(transcript)|ensembl:ENST00000395604(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0016605"(PML body)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0030154"(cell differentiation)|go:"GO:0034115"(negative regulation of heterotypic cell-cell adhesion)|entrezgene/locuslink:5598(identity)	sgd:S000003374|refseq:NP_011658.3|dip:DIP-5534N|mint:P53286|ensemblfungi:YGR142W(gene)|ensemblfungi:YGR142W_mRNA(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005634"(nucleus)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006865"(amino acid transport)|go:"GO:0006885"(regulation of pH)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051087"(chaperone binding)|go:"GO:0140311"(protein sequestering activity)|sgd:YGR142W(identity)	-	-	crc64:E7AE1EB1E3612F3E	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:dUTMnlgdjEkFhq0i6RmvpX5U7BM9606	rogid:Cu27xkwGMNyS4zLvUaG1UeH2mE0559292	intact-crc:1A9EE89CC9966B3C|rigid:JEZNN4b3KaX3CQ1ZRZjBKbJOam0	false	sufficient binding region:140-816	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P53286	uniprotkb:P63279	intact:EBI-3796|uniprotkb:D6VUS2|ensemblfungi:YGR142W	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	psi-mi:btn2_yeast(display_long)|uniprotkb:YGR142W(locus name)|uniprotkb:BTN2(gene name)|psi-mi:BTN2(display_short)|uniprotkb:Batten disease protein 2(gene name synonym)	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11543763|imex:IM-24995-2258	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003374|refseq:NP_011658.3|dip:DIP-5534N|mint:P53286|ensemblfungi:YGR142W(gene)|ensemblfungi:YGR142W_mRNA(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005634"(nucleus)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006865"(amino acid transport)|go:"GO:0006885"(regulation of pH)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051087"(chaperone binding)|go:"GO:0140311"(protein sequestering activity)|sgd:YGR142W(identity)	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N|entrezgene/locuslink:7329(identity)	-	crc64:E7AE1EB1E3612F3E	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Cu27xkwGMNyS4zLvUaG1UeH2mE0559292	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	intact-crc:5D590D573473DEC8|rigid:gK6tt7o2LgaREYUhL/GCgAqYw1o	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P53286	uniprotkb:P14373	intact:EBI-3796|uniprotkb:D6VUS2|ensemblfungi:YGR142W	intact:EBI-719493|uniprotkb:A2BE15|uniprotkb:Q5RJA8|uniprotkb:Q5ST26|uniprotkb:Q6LA73|uniprotkb:Q6NXR9|uniprotkb:Q9BZY6|uniprotkb:Q9UJL3|ensembl:ENSP00000383555|ensembl:ENSP00000392787|ensembl:ENSP00000405229|ensembl:ENSP00000414793|ensembl:ENSP00000366404	psi-mi:btn2_yeast(display_long)|uniprotkb:YGR142W(locus name)|uniprotkb:BTN2(gene name)|psi-mi:BTN2(display_short)|uniprotkb:Batten disease protein 2(gene name synonym)	psi-mi:tri27_human(display_long)|uniprotkb:TRIM27(gene name)|psi-mi:TRIM27(display_short)|uniprotkb:RNF76(gene name synonym)|uniprotkb:RFP(gene name synonym)|uniprotkb:Ret finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 27(gene name synonym)|uniprotkb:RING finger protein 76(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM27(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11543754|imex:IM-24995-2257	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003374|refseq:NP_011658.3|dip:DIP-5534N|mint:P53286|ensemblfungi:YGR142W(gene)|ensemblfungi:YGR142W_mRNA(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005634"(nucleus)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006865"(amino acid transport)|go:"GO:0006885"(regulation of pH)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051087"(chaperone binding)|go:"GO:0140311"(protein sequestering activity)|sgd:YGR142W(identity)	refseq:NP_006501.1|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0090281"(negative regulation of calcium ion import)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR020457|interpro:IPR035791|interpro:IPR043136|mint:P14373|reactome:R-HSA-3232142|reactome:R-HSA-9635465|reactome:R-HSA-8948751|ensembl:ENSG00000204713(gene)|ensembl:ENSG00000215641(gene)|ensembl:ENSG00000229006(gene)|ensembl:ENSG00000234495(gene)|ensembl:ENSG00000237071(gene)|ensembl:ENST00000377199(transcript)|ensembl:ENST00000400720(transcript)|ensembl:ENST00000431123(transcript)|ensembl:ENST00000435528(transcript)|ensembl:ENST00000437160(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001650"(fibrillar center)|go:"GO:0002820"(negative regulation of adaptive immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|entrezgene/locuslink:5987(identity)	-	crc64:E7AE1EB1E3612F3E	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Cu27xkwGMNyS4zLvUaG1UeH2mE0559292	rogid:dsfH5OUghD8KSaTz1SFw9OYVTK49606	intact-crc:05937E2A8C24558A|rigid:EeK2OKS7QHYLx/SeETjhKZnWZCY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q6P1W5	uniprotkb:P53286	intact:EBI-946029|uniprotkb:B3KVT1|uniprotkb:Q96IC8|ensembl:ENSP00000435634|uniprotkb:D3DPR3|uniprotkb:E9PJ76	intact:EBI-3796|uniprotkb:D6VUS2|ensemblfungi:YGR142W	psi-mi:ca094_human(display_long)|uniprotkb:C1orf94(gene name)|psi-mi:C1orf94(display_short)	psi-mi:btn2_yeast(display_long)|uniprotkb:YGR142W(locus name)|uniprotkb:BTN2(gene name)|psi-mi:BTN2(display_short)|uniprotkb:Batten disease protein 2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11543823|imex:IM-24995-2264	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001128206.1|refseq:NP_116273.2|ensembl:ENSG00000142698(gene)|ensembl:ENST00000488417(transcript)|interpro:IPR031496|entrezgene/locuslink:84970(identity)	sgd:S000003374|refseq:NP_011658.3|dip:DIP-5534N|mint:P53286|ensemblfungi:YGR142W(gene)|ensemblfungi:YGR142W_mRNA(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005634"(nucleus)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006865"(amino acid transport)|go:"GO:0006885"(regulation of pH)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051087"(chaperone binding)|go:"GO:0140311"(protein sequestering activity)|sgd:YGR142W(identity)	-	-	crc64:E7AE1EB1E3612F3E	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:y1o4xWvTl2CBA1J7jsP7y8ZjLzM9606	rogid:Cu27xkwGMNyS4zLvUaG1UeH2mE0559292	intact-crc:5CDBB05683CA884D|rigid:rwo3wJUtUQCT6celj1ZqUnTbioI	false	sufficient binding region:191-598	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P53286	uniprotkb:Q6IBW4	intact:EBI-3796|uniprotkb:D6VUS2|ensemblfungi:YGR142W	intact:EBI-2548296|ensembl:ENSP00000410088|uniprotkb:Q9BUT3|uniprotkb:Q9BVD1|uniprotkb:B7WPH1|uniprotkb:O43788|uniprotkb:Q13391|uniprotkb:Q96C14|uniprotkb:Q96GJ0|uniprotkb:Q9BQ71	psi-mi:btn2_yeast(display_long)|uniprotkb:YGR142W(locus name)|uniprotkb:BTN2(gene name)|psi-mi:BTN2(display_short)|uniprotkb:Batten disease protein 2(gene name synonym)	psi-mi:cndh2_human(display_long)|uniprotkb:NCAPH2(gene name)|psi-mi:NCAPH2(display_short)|uniprotkb:CAPH2(gene name synonym)|uniprotkb:Non-SMC condensin II complex subunit H2(gene name synonym)|uniprotkb:Chromosome-associated protein H2(gene name synonym)|uniprotkb:Kleisin-beta(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11543812|imex:IM-24995-2263	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003374|refseq:NP_011658.3|dip:DIP-5534N|mint:P53286|ensemblfungi:YGR142W(gene)|ensemblfungi:YGR142W_mRNA(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005634"(nucleus)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006865"(amino acid transport)|go:"GO:0006885"(regulation of pH)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051087"(chaperone binding)|go:"GO:0140311"(protein sequestering activity)|sgd:YGR142W(identity)	ensembl:ENSG00000025770(gene)|ensembl:ENST00000420993(transcript)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000796"(condensin complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0010032"(meiotic chromosome condensation)|go:"GO:0016020"(membrane)|go:"GO:0030054"(cell junction)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0045171"(intercellular bridge)|go:"GO:0051306"(mitotic sister chromatid separation)|go:"GO:0051309"(female meiosis chromosome separation)|interpro:IPR009378(Protein of unknown function DUF1032)|interpro:IPR031719|interpro:IPR031737|interpro:IPR031739|mint:Q6IBW4|reactome:R-HSA-2299718|refseq:NP_001171940.1|refseq:NP_055366.3|refseq:NP_689512.2|dip:DIP-43901N|entrezgene/locuslink:29781(identity)	-	crc64:E7AE1EB1E3612F3E	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Cu27xkwGMNyS4zLvUaG1UeH2mE0559292	rogid:GTOZg0OoAHm+tj3C8/3sCGM+G5E9606	intact-crc:EEB30BEB193620B0|rigid:8Lov5MtCZxiAfmGnN71zLKWgNAk	false	-	sufficient binding region:150-605	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q5VWN6	uniprotkb:P53286	intact:EBI-745958|uniprotkb:Q2YD91|uniprotkb:Q5VWN5|uniprotkb:Q6ZRQ8|uniprotkb:Q8IVG4|uniprotkb:Q9BUZ7|uniprotkb:Q9H5J9|uniprotkb:Q9H7A4|uniprotkb:Q9H996|uniprotkb:Q9NXA1|intact:EBI-28974916|ensembl:ENSP00000328426	intact:EBI-3796|uniprotkb:D6VUS2|ensemblfungi:YGR142W	psi-mi:taso2_human(display_long)|uniprotkb:TASOR2(gene name)|psi-mi:TASOR2(display_short)|uniprotkb:C10orf18(gene name synonym)|uniprotkb:FAM208B(gene name synonym)|uniprotkb:KIAA2006(gene name synonym)	psi-mi:btn2_yeast(display_long)|uniprotkb:YGR142W(locus name)|uniprotkb:BTN2(gene name)|psi-mi:BTN2(display_short)|uniprotkb:Batten disease protein 2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11543801|imex:IM-24995-2262	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060252.4|ensembl:ENSP00000328426|refseq:XP_011517827.1|refseq:XP_016871852.1|refseq:XP_016871854.1|ensembl:ENSG00000108021(gene)|ensembl:ENST00000328090(transcript)|go:"GO:0005829"(cytosol)|interpro:IPR022168|interpro:IPR022188|mint:Q5VWN6|go:"GO:0005654"(nucleoplasm)|refseq:XP_005252532.1|refseq:XP_005252537.1|refseq:XP_005252538.1|refseq:XP_005252539.1|refseq:NP_001308712.1|refseq:NP_001308713.1|refseq:NP_001308714.1|entrezgene/locuslink:54906(identity)	sgd:S000003374|refseq:NP_011658.3|dip:DIP-5534N|mint:P53286|ensemblfungi:YGR142W(gene)|ensemblfungi:YGR142W_mRNA(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005634"(nucleus)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006865"(amino acid transport)|go:"GO:0006885"(regulation of pH)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051087"(chaperone binding)|go:"GO:0140311"(protein sequestering activity)|sgd:YGR142W(identity)	-	-	crc64:E7AE1EB1E3612F3E	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:mTRMzWB45dZojaB1ZrsaQRT48YQ9606	rogid:Cu27xkwGMNyS4zLvUaG1UeH2mE0559292	intact-crc:0ABAAEB44ED04059|rigid:7+7MsobuGDkG6QcBDTEJk0uu9fc	false	sufficient binding region:1690-2430	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P53286	uniprotkb:Q8WXE1-3	intact:EBI-3796|uniprotkb:D6VUS2|ensemblfungi:YGR142W	intact:EBI-11524582|ensembl:ENSP00000400930	psi-mi:btn2_yeast(display_long)|uniprotkb:YGR142W(locus name)|uniprotkb:BTN2(gene name)|psi-mi:BTN2(display_short)|uniprotkb:Batten disease protein 2(gene name synonym)	psi-mi:q8wxe1-3(display_long)|uniprotkb:ATRIP(gene name)|psi-mi:ATRIP(display_short)|uniprotkb:AGS1(gene name synonym)|uniprotkb:ATM and Rad3-related-interacting protein(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11543883|imex:IM-24995-2270	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003374|refseq:NP_011658.3|dip:DIP-5534N|mint:P53286|ensemblfungi:YGR142W(gene)|ensemblfungi:YGR142W_mRNA(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005634"(nucleus)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006865"(amino acid transport)|go:"GO:0006885"(regulation of pH)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051087"(chaperone binding)|go:"GO:0140311"(protein sequestering activity)|sgd:YGR142W(identity)	intact:EBI-747353(isoform-parent)|ensembl:ENSG00000164053(gene)|ensembl:ENST00000412052(transcript)|entrezgene/locuslink:84126(identity)	-	crc64:E7AE1EB1E3612F3E	isoform-comment:No experimental confirmation available.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Cu27xkwGMNyS4zLvUaG1UeH2mE0559292	rogid:NKCjy1jGZEySEhUOf8rJ6h9pyxY9606	intact-crc:B37A8645434602FB|rigid:QecK8SllrIfV258shEgboJCRAHg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8WV44	uniprotkb:P53286	intact:EBI-725997|uniprotkb:Q5BKT0|uniprotkb:Q7L484|uniprotkb:Q96Q10|intact:EBI-1551110|uniprotkb:Q9BSL8|uniprotkb:B3KNJ6|uniprotkb:D3DWR9|ensembl:ENSP00000320869	intact:EBI-3796|uniprotkb:D6VUS2|ensemblfungi:YGR142W	psi-mi:tri41_human(display_long)|uniprotkb:TRIM41(gene name)|psi-mi:TRIM41(display_short)|uniprotkb:RINCK(gene name synonym)|uniprotkb:Tripartite motif-containing protein 41(gene name synonym)|uniprotkb:RING finger-interacting protein with C kinase(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM41(gene name synonym)	psi-mi:btn2_yeast(display_long)|uniprotkb:YGR142W(locus name)|uniprotkb:BTN2(gene name)|psi-mi:BTN2(display_short)|uniprotkb:Batten disease protein 2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11543872|imex:IM-24995-2269	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_291027.3|refseq:NP_963921.1|ensembl:ENSG00000146063(gene)|ensembl:ENST00000315073(transcript)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0042802"(identical protein binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071225"(cellular response to muramyl dipeptide)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR042828|interpro:IPR043136|mint:Q8WV44|rcsb pdb:2EGM|reactome:R-HSA-983168|entrezgene/locuslink:90933(identity)	sgd:S000003374|refseq:NP_011658.3|dip:DIP-5534N|mint:P53286|ensemblfungi:YGR142W(gene)|ensemblfungi:YGR142W_mRNA(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005634"(nucleus)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006865"(amino acid transport)|go:"GO:0006885"(regulation of pH)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051087"(chaperone binding)|go:"GO:0140311"(protein sequestering activity)|sgd:YGR142W(identity)	-	-	crc64:E7AE1EB1E3612F3E	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:BVqf0OHXPGsYe8F66mHzvD4XQ549606	rogid:Cu27xkwGMNyS4zLvUaG1UeH2mE0559292	intact-crc:372908A626E00AB4|rigid:iONbbSGxSDbnGs+cYcaSNydYe7s	false	sufficient binding region:86-630	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P53286	uniprotkb:Q8NHQ1	intact:EBI-3796|uniprotkb:D6VUS2|ensemblfungi:YGR142W	intact:EBI-739624|ensembl:ENSP00000264982|ensembl:ENSP00000419231|uniprotkb:Q96B31|uniprotkb:Q9H2C3|uniprotkb:Q9H2Z1|uniprotkb:Q9H940|uniprotkb:D3DNE9|uniprotkb:B7Z5I8|uniprotkb:B7Z7E8|uniprotkb:F5GZX8	psi-mi:btn2_yeast(display_long)|uniprotkb:YGR142W(locus name)|uniprotkb:BTN2(gene name)|psi-mi:BTN2(display_short)|uniprotkb:Batten disease protein 2(gene name synonym)	psi-mi:cep70_human(display_long)|uniprotkb:CEP70(gene name)|psi-mi:CEP70(display_short)|uniprotkb:BITE(gene name synonym)|uniprotkb:p10-binding protein(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11543863|imex:IM-24995-2268	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003374|refseq:NP_011658.3|dip:DIP-5534N|mint:P53286|ensemblfungi:YGR142W(gene)|ensemblfungi:YGR142W_mRNA(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005634"(nucleus)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006865"(amino acid transport)|go:"GO:0006885"(regulation of pH)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051087"(chaperone binding)|go:"GO:0140311"(protein sequestering activity)|sgd:YGR142W(identity)	ensembl:ENSG00000114107(gene)|ensembl:ENST00000264982(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|interpro:IPR019734|interpro:IPR037692|mint:Q8NHQ1|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|ensembl:ENST00000484888(transcript)|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_077817.2|refseq:XP_016862764.1|refseq:NP_001275893.1|refseq:NP_001275894.1|refseq:NP_001275895.1|refseq:NP_001275896.1|refseq:NP_001307527.1|refseq:NP_001307529.1|entrezgene/locuslink:80321(identity)	-	crc64:E7AE1EB1E3612F3E	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Cu27xkwGMNyS4zLvUaG1UeH2mE0559292	rogid:S4yveQWcvdVtAUX65gqrJ5Dv0Mc9606	intact-crc:5A765D37907D942A|rigid:kjA+AlYSmx6ikhMZAUDlty+Ng0g	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8N6K7-2	uniprotkb:P53286	intact:EBI-11528848|ensembl:ENSP00000324874	intact:EBI-3796|uniprotkb:D6VUS2|ensemblfungi:YGR142W	psi-mi:q8n6k7-2(display_long)|uniprotkb:SAMD3(gene name)|psi-mi:SAMD3(display_short)	psi-mi:btn2_yeast(display_long)|uniprotkb:YGR142W(locus name)|uniprotkb:BTN2(gene name)|psi-mi:BTN2(display_short)|uniprotkb:Batten disease protein 2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11543854|imex:IM-24995-2267	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-748741(isoform-parent)|ensembl:ENSG00000164483(gene)|ensembl:ENST00000324172(transcript)|uniprotkb:Q8N6K7-2(isoform-parent)|entrezgene/locuslink:154075(identity)	sgd:S000003374|refseq:NP_011658.3|dip:DIP-5534N|mint:P53286|ensemblfungi:YGR142W(gene)|ensemblfungi:YGR142W_mRNA(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005634"(nucleus)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006865"(amino acid transport)|go:"GO:0006885"(regulation of pH)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051087"(chaperone binding)|go:"GO:0140311"(protein sequestering activity)|sgd:YGR142W(identity)	-	isoform-comment:No experimental confirmation available.	crc64:E7AE1EB1E3612F3E	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:2ZsHFOFMqw/yebw24QlvgpYFVso9606	rogid:Cu27xkwGMNyS4zLvUaG1UeH2mE0559292	intact-crc:38E591EE9764C70C|rigid:MmC7hO4tzKjiNILYyGE8qh1H7wo	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P53286	uniprotkb:Q8IYX7	intact:EBI-3796|uniprotkb:D6VUS2|ensemblfungi:YGR142W	intact:EBI-3957636|ensembl:ENSP00000369907|intact:EBI-10174528|uniprotkb:A8K880|uniprotkb:Q5VY58	psi-mi:btn2_yeast(display_long)|uniprotkb:YGR142W(locus name)|uniprotkb:BTN2(gene name)|psi-mi:BTN2(display_short)|uniprotkb:Batten disease protein 2(gene name synonym)	psi-mi:saxo1_human(display_long)|uniprotkb:SAXO1(gene name)|psi-mi:SAXO1(display_short)|uniprotkb:C9orf138(gene name synonym)|uniprotkb:FAM154A(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11543845|imex:IM-24995-2266	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003374|refseq:NP_011658.3|dip:DIP-5534N|mint:P53286|ensemblfungi:YGR142W(gene)|ensemblfungi:YGR142W_mRNA(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005634"(nucleus)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006865"(amino acid transport)|go:"GO:0006885"(regulation of pH)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051087"(chaperone binding)|go:"GO:0140311"(protein sequestering activity)|sgd:YGR142W(identity)	ensembl:ENSG00000155875(gene)|ensembl:ENST00000380534(transcript)|go:"GO:0005814"(centriole)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0008017"(microtubule binding)|go:"GO:0009631"(cold acclimation)|go:"GO:0030030"(cell projection organization)|go:"GO:0031514"(motile cilium)|go:"GO:0034453"(microtubule anchoring)|go:"GO:0036064"(ciliary basal body)|go:"GO:0036126"(sperm flagellum)|go:"GO:0045724"(positive regulation of cilium assembly)|go:"GO:0050821"(protein stabilization)|go:"GO:0070417"(cellular response to cold)|interpro:IPR033336|refseq:NP_714918.2|refseq:NP_001273978.1|refseq:NP_001273979.1|entrezgene/locuslink:158297(identity)	-	crc64:E7AE1EB1E3612F3E	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Cu27xkwGMNyS4zLvUaG1UeH2mE0559292	rogid:34It0miSDTtv5wwJ+ERHXJzWRiQ9606	intact-crc:8429EBD80A4A14F9|rigid:TDKUHObbGC3hTL1Ypp6YkuVWUjU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8IYA8	uniprotkb:P53286	intact:EBI-8638439|intact:EBI-28969497|ensembl:ENSP00000296449|ensembl:ENSP00000391788|ensembl:ENSP00000407837|uniprotkb:C9JJL0|uniprotkb:Q96LP7|intact:MINT-8162095|uniprotkb:Q05DG9	intact:EBI-3796|uniprotkb:D6VUS2|ensemblfungi:YGR142W	psi-mi:iho1_human(display_long)|uniprotkb:IHO1(gene name)|psi-mi:IHO1(display_short)|uniprotkb:CCDC36(gene name synonym)|uniprotkb:Cancer/testis antigen 74(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 36(gene name synonym)	psi-mi:btn2_yeast(display_long)|uniprotkb:YGR142W(locus name)|uniprotkb:BTN2(gene name)|psi-mi:BTN2(display_short)|uniprotkb:Batten disease protein 2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11543834|imex:IM-24995-2265	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000296449|ensembl:ENST00000366429|ensembl:ENSP00000403700|ensembl:ENSP00000391788|ensembl:ENSP00000407837|ensembl:ENSG00000173421(gene)|ensembl:ENST00000296449(transcript)|ensembl:ENST00000438782(transcript)|ensembl:ENST00000452691(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0006310"(DNA recombination)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0042138"(meiotic DNA double-strand break formation)|go:"GO:0048477"(oogenesis)|go:"GO:0060629"(regulation of homologous chromosome segregation)|interpro:IPR031529|mint:Q8IYA8|refseq:XP_011531974.1|refseq:XP_011531975.1|refseq:NP_001128669.1|refseq:NP_835467.2|refseq:XP_006713187.1|entrezgene/locuslink:339834(identity)	sgd:S000003374|refseq:NP_011658.3|dip:DIP-5534N|mint:P53286|ensemblfungi:YGR142W(gene)|ensemblfungi:YGR142W_mRNA(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005634"(nucleus)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006865"(amino acid transport)|go:"GO:0006885"(regulation of pH)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051087"(chaperone binding)|go:"GO:0140311"(protein sequestering activity)|sgd:YGR142W(identity)	-	comment:mint	crc64:E7AE1EB1E3612F3E	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:+TNQLExkhmC1NWqsE240Cx7zFVU9606	rogid:Cu27xkwGMNyS4zLvUaG1UeH2mE0559292	intact-crc:06F1C64DF009ED33|rigid:/wTZoa7rX6rntZfQHb0One7J6Ew	false	sufficient binding region:11-594	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O95197-3	uniprotkb:P53296	intact:EBI-11525735|ensembl:ENSP00000440874	intact:EBI-3165|uniprotkb:E9P955|ensemblfungi:YGR177C|uniprotkb:D6VUW1	psi-mi:o95197-3(display_long)|uniprotkb:RTN3(gene name)|psi-mi:RTN3(display_short)|uniprotkb:ASYIP(gene name synonym)|uniprotkb:Homolog of ASY protein(gene name synonym)|uniprotkb:NSPL2(gene name synonym)|uniprotkb:Neuroendocrine-specific protein-like 2(gene name synonym)|uniprotkb:Neuroendocrine-specific protein-like II(gene name synonym)|uniprotkb:A1(isoform synonym)|uniprotkb:B1(isoform synonym)	psi-mi:atf2_yeast(display_long)|uniprotkb:ATF2(gene name)|psi-mi:ATF2(display_short)|uniprotkb:"Acetyl-CoA:pregnenolone acetyltransferase"(gene name synonym)|uniprotkb:G7135(orf name)|uniprotkb:YGR177C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11543928|imex:IM-24995-2275	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000133318(gene)|ensembl:ENST00000537981(transcript)|intact:EBI-740467(isoform-parent)|uniprotkb:O95197-3(isoform-parent)|entrezgene/locuslink:10313(identity)	refseq:NP_011693.1|sgd:S000003409|ensemblfungi:YGR177C(gene)|ensemblfungi:YGR177C_mRNA(transcript)|go:"GO:0004026"(alcohol O-acetyltransferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0008080"(N-acetyltransferase activity)|go:"GO:0008202"(steroid metabolic process)|go:"GO:0009636"(response to toxic substance)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0034209"(sterol acetylation)|go:"GO:1901089"(acetate ester metabolic process involved in fermentation)|interpro:IPR010828(Alcohol acetyltransferase)|dip:DIP-5544N|mint:P53296|sgd:YGR177C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:+TJnANu85CM52dRZ6s+hYMlUABE9606	rogid:tFI+2rcFXzDfDteDJv8wwBGUh0c559292	intact-crc:D0A50F8D9424E40A|rigid:DyoaHsZ294v67cad9fx6YHSXQkY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
intact:EBI-11533440	uniprotkb:P53296	-	intact:EBI-3165|uniprotkb:E9P955|ensemblfungi:YGR177C|uniprotkb:D6VUW1	psi-mi:wac(display_short)|psi-mi:EBI-11533440(display_long)	psi-mi:atf2_yeast(display_long)|uniprotkb:ATF2(gene name)|psi-mi:ATF2(display_short)|uniprotkb:"Acetyl-CoA:pregnenolone acetyltransferase"(gene name synonym)|uniprotkb:G7135(orf name)|uniprotkb:YGR177C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11543919|imex:IM-24995-2274	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	entrezgene/locuslink:51322(identity)	refseq:NP_011693.1|sgd:S000003409|ensemblfungi:YGR177C(gene)|ensemblfungi:YGR177C_mRNA(transcript)|go:"GO:0004026"(alcohol O-acetyltransferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0008080"(N-acetyltransferase activity)|go:"GO:0008202"(steroid metabolic process)|go:"GO:0009636"(response to toxic substance)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0034209"(sterol acetylation)|go:"GO:1901089"(acetate ester metabolic process involved in fermentation)|interpro:IPR010828(Alcohol acetyltransferase)|dip:DIP-5544N|mint:P53296|sgd:YGR177C(identity)	-	no-uniprot-update:	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:1lJ64iBkqUGKNB4Lz3jsp7Xu2nE9606	rogid:tFI+2rcFXzDfDteDJv8wwBGUh0c559292	intact-crc:75527B9008499C3E|rigid:trBMDDEA9DoT5CNCQ5Q/nxnBYo8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P53286	uniprotkb:Q9UKT9	intact:EBI-3796|uniprotkb:D6VUS2|ensemblfungi:YGR142W	intact:EBI-747204|uniprotkb:Q8WWQ9|uniprotkb:Q8WWR0|uniprotkb:Q8WWR1|uniprotkb:Q8WWR2|uniprotkb:Q8WWR3|uniprotkb:Q8N574|uniprotkb:B4DVV5|uniprotkb:Q69BL6|uniprotkb:Q69BL7|uniprotkb:Q69BL8|uniprotkb:Q69BL9|uniprotkb:Q69BM0|uniprotkb:Q69BM1|uniprotkb:Q69BM2|uniprotkb:Q69BM3|uniprotkb:Q69BM5|ensembl:ENSP00000344544	psi-mi:btn2_yeast(display_long)|uniprotkb:YGR142W(locus name)|uniprotkb:BTN2(gene name)|psi-mi:BTN2(display_short)|uniprotkb:Batten disease protein 2(gene name synonym)	psi-mi:ikzf3_human(display_long)|uniprotkb:ZNFN1A3(gene name synonym)|uniprotkb:Ikaros family zinc finger protein 3(gene name synonym)|uniprotkb:IKZF3(gene name)|psi-mi:IKZF3(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11543910|imex:IM-24995-2273	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003374|refseq:NP_011658.3|dip:DIP-5534N|mint:P53286|ensemblfungi:YGR142W(gene)|ensemblfungi:YGR142W_mRNA(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005634"(nucleus)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006865"(amino acid transport)|go:"GO:0006885"(regulation of pH)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051087"(chaperone binding)|go:"GO:0140311"(protein sequestering activity)|sgd:YGR142W(identity)	refseq:NP_001271443.1|refseq:NP_001271444.1|refseq:NP_036613.2|refseq:NP_899051.1|refseq:NP_899052.1|refseq:NP_899053.1|refseq:NP_899054.1|refseq:NP_899055.1|refseq:NP_001271445.1|refseq:NP_001244337.1|refseq:NP_001244338.1|refseq:NP_001244339.1|refseq:NP_001244340.1|refseq:NP_001244341.1|refseq:NP_001244342.1|refseq:NP_001244343.1|ensembl:ENSG00000161405(gene)|ensembl:ENST00000346872(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007498"(mesoderm development)|go:"GO:0009617"(response to bacterium)|go:"GO:0030888"(regulation of B cell proliferation)|go:"GO:0042113"(B cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045577"(regulation of B cell differentiation)|go:"GO:0045619"(regulation of lymphocyte differentiation)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|go:"GO:0046872"(metal ion binding)|dip:DIP-56975N|entrezgene/locuslink:22806(identity)	-	crc64:E7AE1EB1E3612F3E	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Cu27xkwGMNyS4zLvUaG1UeH2mE0559292	rogid:2Kp6LefSLfK5VIiE6DmQusFIfMY9606	intact-crc:05D2EE84CCDD3BBE|rigid:M2ObKjk04l5z10jOQwXnunL8BtE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P53286	uniprotkb:Q9NRA8	intact:EBI-3796|uniprotkb:D6VUS2|ensemblfungi:YGR142W	intact:EBI-301024|uniprotkb:B1AKL2|uniprotkb:Q8NCF2|uniprotkb:Q9H708|uniprotkb:B2RBF1|ensembl:ENSP00000328103|ensembl:ENSP00000380659|intact:EBI-877635|uniprotkb:B1AKL3	psi-mi:btn2_yeast(display_long)|uniprotkb:YGR142W(locus name)|uniprotkb:BTN2(gene name)|psi-mi:BTN2(display_short)|uniprotkb:Batten disease protein 2(gene name synonym)	psi-mi:4et_human(display_long)|uniprotkb:EIF4ENIF1(gene name)|psi-mi:EIF4ENIF1(display_short)|uniprotkb:Eukaryotic translation initiation factor 4E nuclear import factor 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11543901|imex:IM-24995-2272	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003374|refseq:NP_011658.3|dip:DIP-5534N|mint:P53286|ensemblfungi:YGR142W(gene)|ensemblfungi:YGR142W_mRNA(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005634"(nucleus)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006865"(amino acid transport)|go:"GO:0006885"(regulation of pH)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051087"(chaperone binding)|go:"GO:0140311"(protein sequestering activity)|sgd:YGR142W(identity)	ensembl:ENSP00000328103|ensembl:ENST00000344710|ensembl:ENSP00000342927|ensembl:ENSP00000380659|ensembl:ENSG00000184708(gene)|ensembl:ENST00000330125(transcript)|ensembl:ENST00000397525(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0016020"(membrane)|go:"GO:0016605"(PML body)|go:"GO:0016607"(nuclear speck)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019900"(kinase binding)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0033962"(P-body assembly)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0106289"(negative regulation of deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:1905618"(positive regulation of miRNA-mediated gene silencing by inhibition of translation)|interpro:IPR018862|mint:Q9NRA8|rcsb pdb:5ANR|rcsb pdb:6F9W|rcsb pdb:6X2R|refseq:NP_001157973.1|refseq:NP_001157974.1|refseq:NP_062817.2|refseq:XP_011528582.1|refseq:XP_011528583.1|refseq:XP_005261743.1|refseq:XP_005261744.1|refseq:XP_005261745.1|refseq:XP_016884353.1|entrezgene/locuslink:56478(identity)	-	crc64:E7AE1EB1E3612F3E	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Cu27xkwGMNyS4zLvUaG1UeH2mE0559292	rogid:4A9mF81S/ePAraruTNYgovUdkT49606	intact-crc:D316CBC31AFAF996|rigid:rK4UkiAgNVvsp9+KRrX3rwJzKz4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96Q35-2	uniprotkb:P53286	intact:EBI-11533409|ensembl:ENSP00000376086|ensembl:ENSP00000412073	intact:EBI-3796|uniprotkb:D6VUS2|ensemblfungi:YGR142W	psi-mi:q96q35-2(display_long)|uniprotkb:FLACC1(gene name)|psi-mi:FLACC1(display_short)|uniprotkb:ALS2CR12(gene name synonym)|uniprotkb:Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 12 protein(gene name synonym)	psi-mi:btn2_yeast(display_long)|uniprotkb:YGR142W(locus name)|uniprotkb:BTN2(gene name)|psi-mi:BTN2(display_short)|uniprotkb:Batten disease protein 2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11543892|imex:IM-24995-2271	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-750451(isoform-parent)|uniprotkb:Q96Q35-2(isoform-parent)|ensembl:ENSG00000155749(gene)|ensembl:ENST00000392257(transcript)|ensembl:ENST00000439709(transcript)|entrezgene/locuslink:130540(identity)	sgd:S000003374|refseq:NP_011658.3|dip:DIP-5534N|mint:P53286|ensemblfungi:YGR142W(gene)|ensemblfungi:YGR142W_mRNA(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005634"(nucleus)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006865"(amino acid transport)|go:"GO:0006885"(regulation of pH)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051087"(chaperone binding)|go:"GO:0140311"(protein sequestering activity)|sgd:YGR142W(identity)	-	isoform-comment:No experimental confirmation available.	crc64:E7AE1EB1E3612F3E	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:bdqsMHSGebh2qVAwEO8DhTbZOHM9606	rogid:Cu27xkwGMNyS4zLvUaG1UeH2mE0559292	intact-crc:B84BDE65051A3ECC|rigid:fCuK39rzQsrSPULT0uqqR2hP8KQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O14641	uniprotkb:P53305	intact:EBI-740850|ensembl:ENSP00000005340|uniprotkb:Q53XM0|uniprotkb:D3DTN3	intact:EBI-23490|uniprotkb:D6VUZ8|ensemblfungi:YGR215W	psi-mi:dvl2_human(display_long)|uniprotkb:DSH homolog 2(gene name synonym)|uniprotkb:DVL2(gene name)|psi-mi:DVL2(display_short)	psi-mi:rt27_yeast(display_long)|uniprotkb:RSM27(gene name)|psi-mi:RSM27(display_short)|uniprotkb:Mitochondrial small ribosomal subunit protein mS33(gene name synonym)|uniprotkb:YGR215W(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11543964|imex:IM-24995-2279	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004413.1|ensembl:ENSG00000004975(gene)|ensembl:ENST00000005340(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005109"(frizzled binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0007507"(heart development)|go:"GO:0016235"(aggresome)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044340"(canonical Wnt signaling pathway involved in regulation of cell proliferation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0150012"(positive regulation of neuron projection arborization)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008341(Dishevelled-2 region)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:O14641|rcsb pdb:2REY|rcsb pdb:3CBX|rcsb pdb:3CBY|rcsb pdb:3CBZ|rcsb pdb:3CC0|rcsb pdb:4WIP|rcsb pdb:5LNP|rcsb pdb:5SUY|rcsb pdb:5SUZ|rcsb pdb:6IW3|rcsb pdb:6JCK|reactome:R-HSA-201681|reactome:R-HSA-201688|reactome:R-HSA-2028269|reactome:R-HSA-4086400|reactome:R-HSA-4608870|reactome:R-HSA-4641258|reactome:R-HSA-4641262|reactome:R-HSA-5099900|reactome:R-HSA-5368598|reactome:R-HSA-5663220|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9673324|ensembl:ENSP00000005340|dip:DIP-34433N|entrezgene/locuslink:1856(identity)	sgd:S000003447|refseq:NP_011731.3|dip:DIP-5606N|mint:P53305|ensemblfungi:YGR215W(gene)|ensemblfungi:YGR215W_mRNA(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR013219(Ribosomal protein S27, mitochondrial)|rcsb pdb:5MRC|rcsb pdb:5MRE|rcsb pdb:5MRF|sgd:YGR215W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:2Vdc8oRnT4Mz/j+EXQXrL3AszOc9606	rogid:IRBztDEm6s+cFbpp3GkrlJgUdp4559292	intact-crc:6568E06E12B5E583|rigid:1lEmCr91dLNwbHoUQylCqMMvyNk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P53296	uniprotkb:Q9UI14	intact:EBI-3165|uniprotkb:E9P955|ensemblfungi:YGR177C|uniprotkb:D6VUW1	intact:EBI-712367|ensembl:ENSP00000222008|uniprotkb:Q7Z4Y2|uniprotkb:Q9Y3R1	psi-mi:atf2_yeast(display_long)|uniprotkb:ATF2(gene name)|psi-mi:ATF2(display_short)|uniprotkb:"Acetyl-CoA:pregnenolone acetyltransferase"(gene name synonym)|uniprotkb:G7135(orf name)|uniprotkb:YGR177C(locus name)	psi-mi:praf1_human(display_long)|uniprotkb:PRA1 family protein 1(gene name synonym)|uniprotkb:RABAC1(gene name)|psi-mi:RABAC1(display_short)|uniprotkb:PRA1(gene name synonym)|uniprotkb:PRAF1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11543955|imex:IM-24995-2278	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011693.1|sgd:S000003409|ensemblfungi:YGR177C(gene)|ensemblfungi:YGR177C_mRNA(transcript)|go:"GO:0004026"(alcohol O-acetyltransferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0008080"(N-acetyltransferase activity)|go:"GO:0008202"(steroid metabolic process)|go:"GO:0009636"(response to toxic substance)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0034209"(sterol acetylation)|go:"GO:1901089"(acetate ester metabolic process involved in fermentation)|interpro:IPR010828(Alcohol acetyltransferase)|dip:DIP-5544N|mint:P53296|sgd:YGR177C(identity)	refseq:NP_006414.2|ensembl:ENSG00000105404(gene)|ensembl:ENST00000222008(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0070064"(proline-rich region binding)|interpro:IPR004895(Prenylated rab acceptor PRA1)|mint:Q9UI14|entrezgene/locuslink:10567(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:tFI+2rcFXzDfDteDJv8wwBGUh0c559292	rogid:WS2rUY7yXRbR7pqWgfUCbnEiDbg9606	intact-crc:4AC60D53427FE45D|rigid:mh1TetBF8MwxyPIhB9F7I1csQsE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9NQC3-3	uniprotkb:P53296	intact:EBI-11526335|ensembl:ENSP00000378107	intact:EBI-3165|uniprotkb:E9P955|ensemblfungi:YGR177C|uniprotkb:D6VUW1	psi-mi:q9nqc3-3(display_long)|uniprotkb:Foocen(gene name synonym)|uniprotkb:KIAA0886(gene name synonym)|uniprotkb:NOGO(gene name synonym)|uniprotkb:Neurite outgrowth inhibitor(gene name synonym)|uniprotkb:Neuroendocrine-specific protein(gene name synonym)|uniprotkb:Neuroendocrine-specific protein C homolog(gene name synonym)|uniprotkb:RTN-x(gene name synonym)|uniprotkb:Reticulon-5(gene name synonym)|uniprotkb:My043(orf name)|uniprotkb:SP1507(orf name)|uniprotkb:Foocen-S(isoform synonym)|uniprotkb:Nogo-C(isoform synonym)|uniprotkb:RTN4(gene name)|psi-mi:RTN4(display_short)|uniprotkb:RTN4C(isoform synonym)	psi-mi:atf2_yeast(display_long)|uniprotkb:ATF2(gene name)|psi-mi:ATF2(display_short)|uniprotkb:"Acetyl-CoA:pregnenolone acetyltransferase"(gene name synonym)|uniprotkb:G7135(orf name)|uniprotkb:YGR177C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11543946|imex:IM-24995-2277	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-715945(isoform-parent)|ensembl:ENSG00000115310(gene)|ensembl:ENST00000394609(transcript)|entrezgene/locuslink:57142(identity)	refseq:NP_011693.1|sgd:S000003409|ensemblfungi:YGR177C(gene)|ensemblfungi:YGR177C_mRNA(transcript)|go:"GO:0004026"(alcohol O-acetyltransferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0008080"(N-acetyltransferase activity)|go:"GO:0008202"(steroid metabolic process)|go:"GO:0009636"(response to toxic substance)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0034209"(sterol acetylation)|go:"GO:1901089"(acetate ester metabolic process involved in fermentation)|interpro:IPR010828(Alcohol acetyltransferase)|dip:DIP-5544N|mint:P53296|sgd:YGR177C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Iq/LlFtXjFyIIfxZ1l3NTKURpyA9606	rogid:tFI+2rcFXzDfDteDJv8wwBGUh0c559292	intact-crc:7CF64D187F2377D2|rigid:YGDqpIyHMtZotWwLPGQNqshzKi0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q15041	uniprotkb:P53296	intact:EBI-714543|ensembl:ENSP00000306788|uniprotkb:B7Z6S5|uniprotkb:B7Z791|uniprotkb:F5GXP4	intact:EBI-3165|uniprotkb:E9P955|ensemblfungi:YGR177C|uniprotkb:D6VUW1	psi-mi:ar6p1_human(display_long)|uniprotkb:ARL6IP(gene name synonym)|uniprotkb:ARL6IP1(gene name)|psi-mi:ARL6IP1(display_short)|uniprotkb:KIAA0069(gene name synonym)|uniprotkb:ARMER(gene name synonym)|uniprotkb:Apoptotic regulator in the membrane of the endoplasmic reticulum(gene name synonym)	psi-mi:atf2_yeast(display_long)|uniprotkb:ATF2(gene name)|psi-mi:ATF2(display_short)|uniprotkb:"Acetyl-CoA:pregnenolone acetyltransferase"(gene name synonym)|uniprotkb:G7135(orf name)|uniprotkb:YGR177C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11543937|imex:IM-24995-2276	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055976.1|ensembl:ENSG00000170540(gene)|ensembl:ENST00000304414(transcript)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006613"(cotranslational protein targeting to membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0071787"(endoplasmic reticulum tubular network formation)|go:"GO:1903371"(regulation of endoplasmic reticulum tubular network organization)|go:"GO:1990809"(endoplasmic reticulum tubular network membrane organization)|interpro:IPR033301|mint:Q15041|go:"GO:0002038"(positive regulation of L-glutamate import across plasma membrane)|refseq:NP_001300787.1|entrezgene/locuslink:23204(identity)	refseq:NP_011693.1|sgd:S000003409|ensemblfungi:YGR177C(gene)|ensemblfungi:YGR177C_mRNA(transcript)|go:"GO:0004026"(alcohol O-acetyltransferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0008080"(N-acetyltransferase activity)|go:"GO:0008202"(steroid metabolic process)|go:"GO:0009636"(response to toxic substance)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0034209"(sterol acetylation)|go:"GO:1901089"(acetate ester metabolic process involved in fermentation)|interpro:IPR010828(Alcohol acetyltransferase)|dip:DIP-5544N|mint:P53296|sgd:YGR177C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:3fjkoyvUx25po7xsPcXgpjEeLJg9606	rogid:tFI+2rcFXzDfDteDJv8wwBGUh0c559292	intact-crc:70238B0AC4FF5036|rigid:xG/zV4XbXvlA5eYSWH2Ko7n+JJ0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8N6L0	uniprotkb:P53337	intact:EBI-749265|uniprotkb:Q96MC3|ensembl:ENSP00000404220	intact:EBI-23662|uniprotkb:E9P8T4|uniprotkb:D6VV61|ensemblfungi:YGR284C	psi-mi:kash5_human(display_long)|uniprotkb:KASH5(gene name)|psi-mi:KASH5(display_short)|uniprotkb:CCDC155(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 155(gene name synonym)|uniprotkb:KASH domain-containing protein 5(gene name synonym)	psi-mi:erv29_yeast(display_long)|uniprotkb:ERV29(gene name)|psi-mi:ERV29(display_short)|uniprotkb:YGR284C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11544010|imex:IM-24995-2284	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_653289.3|ensembl:ENSG00000161609(gene)|ensembl:ENST00000447857(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034397"(telomere localization)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051225"(spindle assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0090172"(microtubule cytoskeleton organization involved in homologous chromosome segregation)|go:"GO:0090220"(chromosome localization to nuclear envelope involved in homologous chromosome segregation)|go:"GO:0090619"(meiotic spindle pole)|interpro:IPR011992(EF-Hand type)|interpro:IPR028168|interpro:IPR028170|interpro:IPR039508|mint:Q8N6L0|rcsb pdb:6R2I|rcsb pdb:6WMF|entrezgene/locuslink:147872(identity)	refseq:NP_011800.3|sgd:S000003516|dip:DIP-8110N|mint:P53337|ensemblfungi:YGR284C(gene)|ensemblfungi:YGR284C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0097020"(COPII receptor activity)|interpro:IPR002995(Surfeit locus 4)|reactome:R-SCE-6798695|reactome:R-SCE-6811434|sgd:YGR284C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Wl9L7AcvDHCZuKjYLn8QgGIbZTc9606	rogid:vlRDf0B9mDUXU6M2tLAiWqX4wN8559292	intact-crc:A7BEF728A89308BC|rigid:tBRhPS3XijxnDuDFWhH4kh8Nlf0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q15437	uniprotkb:P53337	intact:EBI-742673|uniprotkb:Q5W183|uniprotkb:Q9BS15|uniprotkb:Q9BSI2|uniprotkb:Q9H1D7|intact:EBI-1048165|uniprotkb:Q503A9|uniprotkb:D3DW33|ensembl:ENSP00000262544|ensembl:ENSP00000338844|ensembl:ENSP00000366685|ensembl:ENSP00000497473	intact:EBI-23662|uniprotkb:E9P8T4|uniprotkb:D6VV61|ensemblfungi:YGR284C	psi-mi:sc23b_human(display_long)|uniprotkb:SEC23-related protein B(gene name synonym)|uniprotkb:SEC23B(gene name)|psi-mi:SEC23B(display_short)	psi-mi:erv29_yeast(display_long)|uniprotkb:ERV29(gene name)|psi-mi:ERV29(display_short)|uniprotkb:YGR284C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11544000|imex:IM-24995-2283	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001166216.1|refseq:NP_006354.2|refseq:NP_116780.1|refseq:NP_116781.1|ensembl:ENSG00000101310(gene)|ensembl:ENST00000262544(transcript)|ensembl:ENST00000336714(transcript)|ensembl:ENST00000377465(transcript)|ensembl:ENST00000650089(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008270"(zinc ion binding)|go:"GO:0012505"(endomembrane system)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0090110"(COPII-coated vesicle cargo loading)|go:"GO:0070971"(endoplasmic reticulum exit site)|interpro:IPR006895(Zinc finger, Sec23/Sec24-type)|interpro:IPR006896(Sec23/Sec24 trunk region)|interpro:IPR006900(Sec23/Sec24 helical region)|interpro:IPR007123(Gelsolin region)|interpro:IPR012990(Sec23/Sec24 beta-sandwich)|interpro:IPR029006|interpro:IPR036174|interpro:IPR036175|interpro:IPR036180|interpro:IPR036465|interpro:IPR037364|interpro:IPR037550|mint:Q15437|refseq:XP_016883082.1|entrezgene/locuslink:10483(identity)	refseq:NP_011800.3|sgd:S000003516|dip:DIP-8110N|mint:P53337|ensemblfungi:YGR284C(gene)|ensemblfungi:YGR284C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0097020"(COPII receptor activity)|interpro:IPR002995(Surfeit locus 4)|reactome:R-SCE-6798695|reactome:R-SCE-6811434|sgd:YGR284C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:+3KZ/1jjziSgJRcr81Axquofkl49606	rogid:vlRDf0B9mDUXU6M2tLAiWqX4wN8559292	intact-crc:62E085A03BC79846|rigid:6ziWyI9R7/6JLtW/u8QQLPdTMm4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9NVV9	uniprotkb:P53335	intact:EBI-741515|uniprotkb:Q53FQ1|uniprotkb:Q6IA99|ensembl:ENSP00000254250|uniprotkb:A6NCB6|uniprotkb:D3DSY5|uniprotkb:H9KV49	intact:EBI-23652|uniprotkb:D6VV57|uniprotkb:Q8TG89|intact:EBI-33325|ensemblfungi:YGR280C	psi-mi:thap1_human(display_long)|uniprotkb:THAP1(gene name)|psi-mi:THAP1(display_short)	psi-mi:pxr1_yeast(display_long)|uniprotkb:PXR1(gene name)|psi-mi:PXR1(display_short)|uniprotkb:GNO1(gene name synonym)|uniprotkb:PinX1-related protein 1(gene name synonym)|uniprotkb:G-patch nucleolar protein(gene name synonym)|uniprotkb:YGR280C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11543991|imex:IM-24995-2282	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060575.1|ensembl:ENSG00000131931(gene)|ensembl:ENST00000254250(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001650"(fibrillar center)|go:"GO:0001935"(endothelial cell proliferation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007049"(cell cycle)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016605"(PML body)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR006612(Zinc finger, C2CH-type)|interpro:IPR026516|interpro:IPR038441|mint:Q9NVV9|rcsb pdb:2JTG|rcsb pdb:2KO0|rcsb pdb:2L1G|refseq:NP_945354.1|entrezgene/locuslink:55145(identity)	refseq:NP_011796.1|sgd:S000003512|dip:DIP-4308N|mint:P53335|ensemblfungi:YGR280C(gene)|ensemblfungi:YGR280C_mRNA(transcript)|go:"GO:0000494"(box C/D RNA 3'-end processing)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0010521"(telomerase inhibitor activity)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|interpro:IPR000467(D111/G-patch)|sgd:YGR280C(identity)	-	-	crc64:D5AB6EB2C129922D	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:/KO90pu5tBnIVq9SMx1JYPXFCEQ9606	rogid:SzQtp13uvK3KbuNHyZQPJxKMzwY559292	intact-crc:F6C6FF81E14777B0|rigid:3ht2BQNn8IjNP9ovA40HOmWiBTc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8NHQ1	uniprotkb:P53335	intact:EBI-739624|ensembl:ENSP00000264982|ensembl:ENSP00000419231|uniprotkb:Q96B31|uniprotkb:Q9H2C3|uniprotkb:Q9H2Z1|uniprotkb:Q9H940|uniprotkb:D3DNE9|uniprotkb:B7Z5I8|uniprotkb:B7Z7E8|uniprotkb:F5GZX8	intact:EBI-23652|uniprotkb:D6VV57|uniprotkb:Q8TG89|intact:EBI-33325|ensemblfungi:YGR280C	psi-mi:cep70_human(display_long)|uniprotkb:CEP70(gene name)|psi-mi:CEP70(display_short)|uniprotkb:BITE(gene name synonym)|uniprotkb:p10-binding protein(gene name synonym)	psi-mi:pxr1_yeast(display_long)|uniprotkb:PXR1(gene name)|psi-mi:PXR1(display_short)|uniprotkb:GNO1(gene name synonym)|uniprotkb:PinX1-related protein 1(gene name synonym)|uniprotkb:G-patch nucleolar protein(gene name synonym)|uniprotkb:YGR280C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11543982|imex:IM-24995-2281	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114107(gene)|ensembl:ENST00000264982(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|interpro:IPR019734|interpro:IPR037692|mint:Q8NHQ1|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|ensembl:ENST00000484888(transcript)|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_077817.2|refseq:XP_016862764.1|refseq:NP_001275893.1|refseq:NP_001275894.1|refseq:NP_001275895.1|refseq:NP_001275896.1|refseq:NP_001307527.1|refseq:NP_001307529.1|entrezgene/locuslink:80321(identity)	refseq:NP_011796.1|sgd:S000003512|dip:DIP-4308N|mint:P53335|ensemblfungi:YGR280C(gene)|ensemblfungi:YGR280C_mRNA(transcript)|go:"GO:0000494"(box C/D RNA 3'-end processing)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0010521"(telomerase inhibitor activity)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|interpro:IPR000467(D111/G-patch)|sgd:YGR280C(identity)	-	-	crc64:D5AB6EB2C129922D	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:S4yveQWcvdVtAUX65gqrJ5Dv0Mc9606	rogid:SzQtp13uvK3KbuNHyZQPJxKMzwY559292	intact-crc:1124A1832D19AFD4|rigid:w7ywsBjZq3ZfPloH3tu3ec70B7c	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49366	uniprotkb:P53331	intact:EBI-741925|ensembl:ENSP00000210060|uniprotkb:Q13184|uniprotkb:Q13276|uniprotkb:A8K688|uniprotkb:Q9UDG0|uniprotkb:M0R1I5	intact:EBI-23641|uniprotkb:D6VV53|ensemblfungi:YGR276C	psi-mi:dhys_human(display_long)|uniprotkb:DHPS(gene name)|psi-mi:DHPS(display_short)|uniprotkb:DS(gene name synonym)	psi-mi:rexo1_yeast(display_long)|uniprotkb:YGR276C(locus name)|uniprotkb:G9381(orf name)|uniprotkb:RNH70(gene name)|psi-mi:RNH70(display_short)|uniprotkb:REX1(gene name synonym)|uniprotkb:"RNase H(70)"(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11543973|imex:IM-24995-2280	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001193903.1|ensembl:ENSG00000095059(gene)|ensembl:ENST00000210060(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0008216"(spermidine metabolic process)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008612"(peptidyl-lysine modification to peptidyl-hypusine)|go:"GO:0034038"(deoxyhypusine synthase activity)|go:"GO:0042802"(identical protein binding)|interpro:IPR002773(Deoxyhypusine synthase)|interpro:IPR029035|interpro:IPR036982|mint:P49366|rcsb pdb:1DHS|rcsb pdb:1RLZ|rcsb pdb:1ROZ|rcsb pdb:1RQD|refseq:NP_001921.1|refseq:NP_037538.1|rcsb pdb:6P4V|rcsb pdb:6PGR|rcsb pdb:6WKZ|rcsb pdb:6WL6|rcsb pdb:6XXH|rcsb pdb:6XXI|rcsb pdb:6XXJ|rcsb pdb:6XXK|rcsb pdb:6XXL|rcsb pdb:6XXM|reactome:R-HSA-204626|refseq:XP_011526072.1|entrezgene/locuslink:1725(identity)	refseq:NP_011792.1|sgd:S000003508|dip:DIP-5564N|ensemblfungi:YGR276C(gene)|ensemblfungi:YGR276C_mRNA(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0002107"(generation of mature 3'-end of 5S rRNA generated by RNA polymerase III)|go:"GO:0003723"(RNA binding)|go:"GO:0004527"(exonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0008408"(3'-5' exonuclease activity)|go:"GO:0034415"(tRNA 3'-trailer cleavage, exonucleolytic)|go:"GO:0034476"(U5 snRNA 3'-end processing)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR013520(Exonuclease, RNase T and DNA polymerase III)|interpro:IPR034922|interpro:IPR036397|sgd:YGR276C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:4MuV3m6JWYn3kCENrfcLU6GAkto9606	rogid:mkFn9c/1OdcUX9TOL2m2kGd0K90559292	intact-crc:FFED719DC5BF4B16|rigid:2iJTqgivkLzk6BO5esa3v2uJU0s	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q08379	uniprotkb:P53829	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	intact:EBI-28306|uniprotkb:D6W0Q5|ensemblfungi:YNL288W	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:caf40_yeast(display_long)|uniprotkb:YNL288W(locus name)|uniprotkb:N0540(orf name)|uniprotkb:40 kDa CCR4-associated factor(gene name synonym)|uniprotkb:CAF40(gene name)|psi-mi:CAF40(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11544055|imex:IM-24995-2289	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N|entrezgene/locuslink:2801(identity)	refseq:NP_014111.1|sgd:S000005232|dip:DIP-1995N|mint:P53829|ensemblfungi:YNL288W(gene)|ensemblfungi:YNL288W_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR007216(Cell differentiation, Rcd1-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:4CV5|sgd:YNL288W(identity)	-	-	crc64:F3DBABE6AD3C7F3C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2017/05/26	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	rogid:etuSSgFGQOcgxPDexEXUqQg6H5s559292	intact-crc:495974E568A2DFC6|rigid:AIaiRZZYO7SNUfkmNR2PvjYLdGs	false	sufficient binding region:383-1002	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8N6L0	uniprotkb:P53730	intact:EBI-749265|uniprotkb:Q96MC3|ensembl:ENSP00000404220	intact:EBI-28496|uniprotkb:D6W1K4|ensemblfungi:YNR030W	psi-mi:kash5_human(display_long)|uniprotkb:KASH5(gene name)|psi-mi:KASH5(display_short)|uniprotkb:CCDC155(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 155(gene name synonym)|uniprotkb:KASH domain-containing protein 5(gene name synonym)	psi-mi:alg12_yeast(display_long)|uniprotkb:ALG12(gene name)|psi-mi:ALG12(display_short)|uniprotkb:ECM39(gene name synonym)|uniprotkb:YNR030W(locus name)|uniprotkb:N3265(orf name)|uniprotkb:Mannosyltransferase ALG12(gene name synonym)|uniprotkb:Extracellular mutant protein 39(gene name synonym)|uniprotkb:"Dolichyl-P-Man:Man(7)GlcNAc(2)-PP-dolichyl-alpha-1,6-mannosyltransferase"(gene name synonym)|uniprotkb:Asparagine-linked glycosylation protein 12(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11544046|imex:IM-24995-2288	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_653289.3|ensembl:ENSG00000161609(gene)|ensembl:ENST00000447857(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034397"(telomere localization)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051225"(spindle assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0090172"(microtubule cytoskeleton organization involved in homologous chromosome segregation)|go:"GO:0090220"(chromosome localization to nuclear envelope involved in homologous chromosome segregation)|go:"GO:0090619"(meiotic spindle pole)|interpro:IPR011992(EF-Hand type)|interpro:IPR028168|interpro:IPR028170|interpro:IPR039508|mint:Q8N6L0|rcsb pdb:6R2I|rcsb pdb:6WMF|entrezgene/locuslink:147872(identity)	refseq:NP_014427.1|sgd:S000005313|dip:DIP-4259N|mint:P53730|ensemblfungi:YNR030W(gene)|ensemblfungi:YNR030W_mRNA(transcript)|go:"GO:0000009"(alpha-1,6-mannosyltransferase activity)|go:"GO:0000030"(mannosyltransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0006488"(dolichol-linked oligosaccharide biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0052917"("dolichyl-P-Man:Man(7)GlcNAc(2)-PP-dolichol alpha-1,6-mannosyltransferase")|interpro:IPR005599(Alg9-like mannosyltransferase)|interpro:IPR039485|reactome:R-SCE-446193|sgd:YNR030W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Wl9L7AcvDHCZuKjYLn8QgGIbZTc9606	rogid:3OdDOcUZm9NImnU+imd8xJwvb/Q559292	intact-crc:EEE1259984E3D6A3|rigid:zUZNmmlYHAgkp51A+owZX2vazzw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P53617	uniprotkb:O95751	intact:EBI-12228|ensemblfungi:YNL251C|uniprotkb:D6W0U2	intact:EBI-740738|ensembl:ENSP00000359557|uniprotkb:Q6IAR6	psi-mi:nrd1_yeast(display_long)|uniprotkb:N0868(orf name)|uniprotkb:YNL251C(locus name)|uniprotkb:NRD1(gene name)|psi-mi:NRD1(display_short)	psi-mi:ldoc1_human(display_long)|uniprotkb:Leucine zipper protein down-regulated in cancer cells(gene name synonym)|uniprotkb:LDOC1(gene name)|psi-mi:LDOC1(display_short)|uniprotkb:BCUR1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11544037|imex:IM-24995-2287	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YNL251C(gene)|ensemblfungi:YNL251C_mRNA(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001068"(transcription regulatory region RNA binding)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030847"(termination of RNA polymerase II transcription, exosome-dependent)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0031126"("sno(s)RNA 3'-end processing")|go:"GO:0034472"(snRNA 3'-end processing)|go:"GO:0035649"(Nrd1 complex)|go:"GO:0042780"(tRNA 3'-end processing)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071034"(CUT catabolic process)|go:"GO:0071041"(antisense RNA transcript catabolic process)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR006569(Regulation of nuclear pre-mRNA protein)|interpro:IPR008942(ENTH/VHS)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034894|interpro:IPR035979|rcsb pdb:2LO6|rcsb pdb:2M88|rcsb pdb:2MOW|rcsb pdb:3CLJ|rcsb pdb:5O1T|rcsb pdb:5O1W|rcsb pdb:5O1X|rcsb pdb:5O1Y|rcsb pdb:5O1Z|rcsb pdb:5O20|rcsb pdb:6GC3|rcsb pdb:6O3W|rcsb pdb:6O3X|rcsb pdb:6O3Y|refseq:NP_014148.1|sgd:S000005195|mint:P53617|dip:DIP-6778N|sgd:YNL251C(identity)	refseq:NP_036449.1|ensembl:ENSG00000182195(gene)|ensembl:ENST00000370526(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071225"(cellular response to muramyl dipeptide)|interpro:IPR032549|interpro:IPR032567|entrezgene/locuslink:23641(identity)	-	crc64:75082BDB0C42AE37	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:FJJxQtZfVVwYERLXtGkq6cJ9I1U559292	rogid:Ediu0oNiZ/+YVY8l3fNdgP5A+v09606	intact-crc:451E0A2637BE96F3|rigid:EsLaDP+DGoWArV+Xn93wox8hmZs	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O14641	uniprotkb:P53617	intact:EBI-740850|ensembl:ENSP00000005340|uniprotkb:Q53XM0|uniprotkb:D3DTN3	intact:EBI-12228|ensemblfungi:YNL251C|uniprotkb:D6W0U2	psi-mi:dvl2_human(display_long)|uniprotkb:DSH homolog 2(gene name synonym)|uniprotkb:DVL2(gene name)|psi-mi:DVL2(display_short)	psi-mi:nrd1_yeast(display_long)|uniprotkb:N0868(orf name)|uniprotkb:YNL251C(locus name)|uniprotkb:NRD1(gene name)|psi-mi:NRD1(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11544028|imex:IM-24995-2286	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004413.1|ensembl:ENSG00000004975(gene)|ensembl:ENST00000005340(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005109"(frizzled binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0007507"(heart development)|go:"GO:0016235"(aggresome)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044340"(canonical Wnt signaling pathway involved in regulation of cell proliferation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0150012"(positive regulation of neuron projection arborization)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008341(Dishevelled-2 region)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:O14641|rcsb pdb:2REY|rcsb pdb:3CBX|rcsb pdb:3CBY|rcsb pdb:3CBZ|rcsb pdb:3CC0|rcsb pdb:4WIP|rcsb pdb:5LNP|rcsb pdb:5SUY|rcsb pdb:5SUZ|rcsb pdb:6IW3|rcsb pdb:6JCK|reactome:R-HSA-201681|reactome:R-HSA-201688|reactome:R-HSA-2028269|reactome:R-HSA-4086400|reactome:R-HSA-4608870|reactome:R-HSA-4641258|reactome:R-HSA-4641262|reactome:R-HSA-5099900|reactome:R-HSA-5368598|reactome:R-HSA-5663220|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9673324|ensembl:ENSP00000005340|dip:DIP-34433N|entrezgene/locuslink:1856(identity)	ensemblfungi:YNL251C(gene)|ensemblfungi:YNL251C_mRNA(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001068"(transcription regulatory region RNA binding)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030847"(termination of RNA polymerase II transcription, exosome-dependent)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0031126"("sno(s)RNA 3'-end processing")|go:"GO:0034472"(snRNA 3'-end processing)|go:"GO:0035649"(Nrd1 complex)|go:"GO:0042780"(tRNA 3'-end processing)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071034"(CUT catabolic process)|go:"GO:0071041"(antisense RNA transcript catabolic process)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR006569(Regulation of nuclear pre-mRNA protein)|interpro:IPR008942(ENTH/VHS)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034894|interpro:IPR035979|rcsb pdb:2LO6|rcsb pdb:2M88|rcsb pdb:2MOW|rcsb pdb:3CLJ|rcsb pdb:5O1T|rcsb pdb:5O1W|rcsb pdb:5O1X|rcsb pdb:5O1Y|rcsb pdb:5O1Z|rcsb pdb:5O20|rcsb pdb:6GC3|rcsb pdb:6O3W|rcsb pdb:6O3X|rcsb pdb:6O3Y|refseq:NP_014148.1|sgd:S000005195|mint:P53617|dip:DIP-6778N|sgd:YNL251C(identity)	-	-	crc64:75082BDB0C42AE37	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:2Vdc8oRnT4Mz/j+EXQXrL3AszOc9606	rogid:FJJxQtZfVVwYERLXtGkq6cJ9I1U559292	intact-crc:5C6C8E1CBEEE6C62|rigid:v77/dYwCC7t3dG3yE5DadupUjf0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P53583	uniprotkb:P50222	intact:EBI-11174|uniprotkb:D6W0U4|ensemblfungi:YNL249C	intact:EBI-748397|uniprotkb:O75263|ensembl:ENSP00000262041|uniprotkb:Q9UPL6|uniprotkb:B2R8I7|intact:EBI-10172134|intact:EBI-11522964|intact:EBI-11750003|intact:EBI-12702266|uniprotkb:A4D127	psi-mi:mpa43_yeast(display_long)|uniprotkb:N0875(orf name)|uniprotkb:YNL249C(locus name)|uniprotkb:MPA43(gene name)|psi-mi:MPA43(display_short)	psi-mi:meox2_human(display_long)|uniprotkb:Mesenchyme homeobox 2(gene name synonym)|uniprotkb:Growth arrest-specific homeobox(gene name synonym)|uniprotkb:MEOX2(gene name)|psi-mi:MEOX2(display_short)|uniprotkb:GAX(gene name synonym)|uniprotkb:MOX2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11544019|imex:IM-24995-2285	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YNL249C(gene)|ensemblfungi:YNL249C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0016773"(phosphotransferase activity, alcohol group as acceptor)|refseq:NP_014150.1|sgd:S000005193|interpro:IPR018485|interpro:IPR018484|interpro:IPR043129|sgd:YNL249C(identity)	ensembl:ENSG00000106511(gene)|ensembl:ENST00000262041(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0001757"(somite specification)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007275"(multicellular organism development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008015"(blood circulation)|go:"GO:0016607"(nuclear speck)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060173"(limb development)|go:"GO:0061053"(somite development)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR042634|refseq:NP_005915.2|entrezgene/locuslink:4223(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2017/05/26	rogid:QQDVGr5IRob5uHE4ZvFNeyAgkZo559292	rogid:fMv0ruKikzQ3MC0PBvJ3pOAjW+U9606	intact-crc:FC4C7B888F58C63B|rigid:08riUNnYPva+PY8cYs0aWMzSTiE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P14136	uniprotkb:P53829	intact:EBI-744302|uniprotkb:Q53H98|uniprotkb:Q5D055|uniprotkb:Q6ZQS3|uniprotkb:Q7Z5J6|uniprotkb:Q7Z5J7|uniprotkb:Q96KS4|uniprotkb:Q96P18|uniprotkb:Q9UFD0|uniprotkb:B2RD44|uniprotkb:D3DX59|intact:EBI-3909365|uniprotkb:E9PAX3|ensembl:ENSP00000466598|uniprotkb:A7REI1	intact:EBI-28306|uniprotkb:D6W0Q5|ensemblfungi:YNL288W	psi-mi:gfap_human(display_long)|uniprotkb:GFAP(gene name)|psi-mi:GFAP(display_short)	psi-mi:caf40_yeast(display_long)|uniprotkb:YNL288W(locus name)|uniprotkb:N0540(orf name)|uniprotkb:40 kDa CCR4-associated factor(gene name synonym)|uniprotkb:CAF40(gene name)|psi-mi:CAF40(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11544095|imex:IM-24995-2293	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001124491.1|refseq:NP_001229305.1|refseq:NP_002046.1|ensembl:ENSG00000131095(gene)|ensembl:ENST00000588735(transcript)|go:"GO:0005178"(integrin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0009611"(response to wounding)|go:"GO:0010467"(gene expression)|go:"GO:0010625"(positive regulation of Schwann cell proliferation)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0014002"(astrocyte development)|go:"GO:0019900"(kinase binding)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0031102"(neuron projection regeneration)|go:"GO:0042802"(identical protein binding)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0044297"(cell body)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0051580"(regulation of neurotransmitter uptake)|go:"GO:0060020"(Bergmann glial cell differentiation)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0070779"(D-aspartate import across plasma membrane)|go:"GO:0097450"(astrocyte end-foot)|go:"GO:0098574"(cytoplasmic side of lysosomal membrane)|go:"GO:1904714"(regulation of chaperone-mediated autophagy)|interpro:IPR006821(Intermediate filament, DNA-binding region)|interpro:IPR018039|interpro:IPR027701|interpro:IPR039008|mint:P14136|rcsb pdb:6A9P|reactome:R-HSA-1251985|reactome:R-HSA-9613829|entrezgene/locuslink:2670(identity)	refseq:NP_014111.1|sgd:S000005232|dip:DIP-1995N|mint:P53829|ensemblfungi:YNL288W(gene)|ensemblfungi:YNL288W_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR007216(Cell differentiation, Rcd1-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:4CV5|sgd:YNL288W(identity)	-	-	crc64:F3DBABE6AD3C7F3C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Pz4JW0WjMjBYILTDSX9jUmMqWhg9606	rogid:etuSSgFGQOcgxPDexEXUqQg6H5s559292	intact-crc:64D9B436F7458064|rigid:C0lpqj92CSG9FmNjEftjqDxKnp8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P13196	uniprotkb:P53829	intact:EBI-3905054|ensembl:ENSP00000309259|ensembl:ENSP00000378416|ensembl:ENSP00000417719|ensembl:ENSP00000418779	intact:EBI-28306|uniprotkb:D6W0Q5|ensemblfungi:YNL288W	psi-mi:hem1_human(display_long)|uniprotkb:ALAS1(gene name)|psi-mi:ALAS1(display_short)|uniprotkb:ALAS3(gene name synonym)|uniprotkb:ALASH(gene name synonym)|uniprotkb:5-aminolevulinic acid synthase 1(gene name synonym)|uniprotkb:Delta-ALA synthase 1(gene name synonym)|uniprotkb:Delta-aminolevulinate synthase 1(gene name synonym)|uniprotkb:OK/SW-cl.121(orf name)	psi-mi:caf40_yeast(display_long)|uniprotkb:YNL288W(locus name)|uniprotkb:N0540(orf name)|uniprotkb:40 kDa CCR4-associated factor(gene name synonym)|uniprotkb:CAF40(gene name)|psi-mi:CAF40(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11544086|imex:IM-24995-2292	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001291372.1|refseq:NP_001291373.1|refseq:NP_000679.1|refseq:NP_954635.1|go:"GO:0006783"(heme biosynthetic process)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0042541"(hemoglobin biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0048821"(erythrocyte development)|ensembl:ENSG00000023330(gene)|ensembl:ENST00000310271(transcript)|ensembl:ENST00000394965(transcript)|ensembl:ENST00000469224(transcript)|ensembl:ENST00000484952(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0003870"(5-aminolevulinate synthase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|interpro:IPR001917(Aminotransferase, class-II, pyridoxal-phosphate binding site)|interpro:IPR004839(Aminotransferase, class I and II)|interpro:IPR010961(Tetrapyrrole biosynthesis, 5-aminolevulinic acid synthase)|interpro:IPR015118(5-aminolevulinate synthase presequence)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|mint:P13196|reactome:R-HSA-189451|reactome:R-HSA-1989781|reactome:R-HSA-2151201|go:"GO:0006782"(protoporphyrinogen IX biosynthetic process)|entrezgene/locuslink:211(identity)	refseq:NP_014111.1|sgd:S000005232|dip:DIP-1995N|mint:P53829|ensemblfungi:YNL288W(gene)|ensemblfungi:YNL288W_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR007216(Cell differentiation, Rcd1-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:4CV5|sgd:YNL288W(identity)	-	-	crc64:F3DBABE6AD3C7F3C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:HFjJ6zrRF9UYD7LMB6A3CcxcS7c9606	rogid:etuSSgFGQOcgxPDexEXUqQg6H5s559292	intact-crc:0C455A8A2752824F|rigid:veJNsWE3nerBonQco5aUGJc24Cg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P53829	uniprotkb:P00492	intact:EBI-28306|uniprotkb:D6W0Q5|ensemblfungi:YNL288W	intact:EBI-748210|uniprotkb:A6NHF0|uniprotkb:B2R8M9|ensembl:ENSP00000298556	psi-mi:caf40_yeast(display_long)|uniprotkb:YNL288W(locus name)|uniprotkb:N0540(orf name)|uniprotkb:40 kDa CCR4-associated factor(gene name synonym)|uniprotkb:CAF40(gene name)|psi-mi:CAF40(display_short)	psi-mi:hprt_human(display_long)|uniprotkb:HPRT1(gene name)|psi-mi:HPRT1(display_short)|uniprotkb:HPRT(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11544077|imex:IM-24995-2291	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014111.1|sgd:S000005232|dip:DIP-1995N|mint:P53829|ensemblfungi:YNL288W(gene)|ensemblfungi:YNL288W_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR007216(Cell differentiation, Rcd1-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:4CV5|sgd:YNL288W(identity)	refseq:NP_000185.1|ensembl:ENSG00000165704(gene)|ensembl:ENST00000298556(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001913"(T cell mediated cytotoxicity)|go:"GO:0001975"(response to amphetamine)|go:"GO:0004422"(hypoxanthine phosphoribosyltransferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006164"(purine nucleotide biosynthetic process)|go:"GO:0006166"(purine ribonucleoside salvage)|go:"GO:0006168"(adenine salvage)|go:"GO:0006178"(guanine salvage)|go:"GO:0007625"(grooming behavior)|go:"GO:0007626"(locomotory behavior)|go:"GO:0021756"(striatum development)|go:"GO:0021895"(cerebral cortex neuron differentiation)|go:"GO:0021954"(central nervous system neuron development)|go:"GO:0032263"(GMP salvage)|go:"GO:0032264"(IMP salvage)|go:"GO:0042417"(dopamine metabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043103"(hypoxanthine salvage)|go:"GO:0045964"(positive regulation of dopamine metabolic process)|go:"GO:0046038"(GMP catabolic process)|go:"GO:0046040"(IMP metabolic process)|go:"GO:0046100"(hypoxanthine metabolic process)|go:"GO:0046651"(lymphocyte proliferation)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0052657"(guanine phosphoribosyltransferase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000836(Phosphoribosyltransferase)|interpro:IPR005904(Hypoxanthine phosphoribosyl transferase)|interpro:IPR029057|mint:P00492|rcsb pdb:1BZY|rcsb pdb:1D6N|rcsb pdb:1HMP|rcsb pdb:1Z7G|go:"GO:0048813"(dendrite morphogenesis)|rcsb pdb:2VFA|rcsb pdb:3GEP|rcsb pdb:3GGC|rcsb pdb:3GGJ|rcsb pdb:4IJQ|rcsb pdb:4KN6|rcsb pdb:4RAB|rcsb pdb:4RAC|rcsb pdb:4RAD|rcsb pdb:4RAN|rcsb pdb:4RAO|rcsb pdb:4RAQ|rcsb pdb:5BRN|rcsb pdb:5BSK|rcsb pdb:5HIA|rcsb pdb:5W8V|rcsb pdb:6BNJ|reactome:R-HSA-74217|entrezgene/locuslink:3251(identity)	-	crc64:F3DBABE6AD3C7F3C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:etuSSgFGQOcgxPDexEXUqQg6H5s559292	rogid:w87Sv/qOAkHFqJm0vu0Ayqlz7TA9606	intact-crc:A7396AA4800AFE10|rigid:amwpDhy02cE1/Ha06fNBQk+Smf8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P53829	uniprotkb:Q7Z6G3-2	intact:EBI-28306|uniprotkb:D6W0Q5|ensemblfungi:YNL288W	intact:EBI-10172876|ensembl:ENSP00000457354|intact:EBI-14062040	psi-mi:caf40_yeast(display_long)|uniprotkb:YNL288W(locus name)|uniprotkb:N0540(orf name)|uniprotkb:40 kDa CCR4-associated factor(gene name synonym)|uniprotkb:CAF40(gene name)|psi-mi:CAF40(display_short)	psi-mi:q7z6g3-2(display_long)|uniprotkb:EFCBP2(gene name synonym)|uniprotkb:Neuronal calcium-binding protein 2(gene name synonym)|uniprotkb:Synaptotagmin-interacting protein 2(gene name synonym)|uniprotkb:NECAB2(gene name)|psi-mi:NECAB2(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11544066|imex:IM-24995-2290	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014111.1|sgd:S000005232|dip:DIP-1995N|mint:P53829|ensemblfungi:YNL288W(gene)|ensemblfungi:YNL288W_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR007216(Cell differentiation, Rcd1-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:4CV5|sgd:YNL288W(identity)	ensembl:ENSG00000103154(gene)|ensembl:ENST00000565691(transcript)|uniprotkb:Q7Z6G3-2(isoform-parent)|intact:EBI-950070(isoform-parent)|entrezgene/locuslink:54550(identity)	-	crc64:F3DBABE6AD3C7F3C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:etuSSgFGQOcgxPDexEXUqQg6H5s559292	rogid:4S7oIx6h+mKzV3EPxqcfMNqaNko9606	intact-crc:8AE4F5C54D451942|rigid:IDVmdYPY6eAPOqTBtXgJKUh2BfQ	false	-	sufficient binding region:65-303	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P53829	uniprotkb:Q5D1E8	intact:EBI-28306|uniprotkb:D6W0Q5|ensemblfungi:YNL288W	intact:EBI-747793|uniprotkb:Q6I9Z1|uniprotkb:Q9H5P1|uniprotkb:D3DPT0|ensembl:ENSP00000362179	psi-mi:caf40_yeast(display_long)|uniprotkb:YNL288W(locus name)|uniprotkb:N0540(orf name)|uniprotkb:40 kDa CCR4-associated factor(gene name synonym)|uniprotkb:CAF40(gene name)|psi-mi:CAF40(display_short)	psi-mi:zc12a_human(display_long)|uniprotkb:MCPIP(gene name synonym)|uniprotkb:MCPIP1(gene name synonym)|uniprotkb:ZC3H12A(gene name)|psi-mi:ZC3H12A(display_short)|uniprotkb:Monocyte chemotactic protein-induced protein 1(gene name synonym)|uniprotkb:Regnase-1(gene name synonym)|uniprotkb:Zinc finger CCCH domain-containing protein 12A(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11544149|imex:IM-24995-2299	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014111.1|sgd:S000005232|dip:DIP-1995N|mint:P53829|ensemblfungi:YNL288W(gene)|ensemblfungi:YNL288W_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR007216(Cell differentiation, Rcd1-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:4CV5|sgd:YNL288W(identity)	refseq:NP_079355.2|refseq:NP_001310479.1|ensembl:ENSG00000163874(gene)|ensembl:ENST00000373087(transcript)|go:"GO:0000294"(nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay)|go:"GO:0000932"(P-body)|go:"GO:0001525"(angiogenesis)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0002757"(immune response-activating signal transduction)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0004532"(exoribonuclease activity)|go:"GO:0004540"(ribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007399"(nervous system development)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010656"(negative regulation of muscle cell apoptotic process)|go:"GO:0010884"(positive regulation of lipid storage)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0030154"(cell differentiation)|go:"GO:0030867"(rough endoplasmic reticulum membrane)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032691"(negative regulation of interleukin-1 beta production)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035198"(miRNA binding)|go:"GO:0035613"(RNA stem-loop binding)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042406"(extrinsic component of endoplasmic reticulum membrane)|go:"GO:0043022"(ribosome binding)|go:"GO:0043031"(negative regulation of macrophage activation)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0044828"(negative regulation by host of viral genome replication)|go:"GO:0045019"(negative regulation of nitric oxide biosynthetic process)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051607"(defense response to virus)|go:"GO:0055118"(negative regulation of cardiac muscle contraction)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0090501"(RNA phosphodiester bond hydrolysis)|go:"GO:0090502"(RNA phosphodiester bond hydrolysis, endonucleolytic)|go:"GO:0098586"(cellular response to virus)|go:"GO:1900016"(negative regulation of cytokine production involved in inflammatory response)|go:"GO:1900119"(positive regulation of execution phase of apoptosis)|go:"GO:1901223"(negative regulation of NIK/NF-kappaB signaling)|go:"GO:1903003"(positive regulation of protein deubiquitination)|go:"GO:1903799"(negative regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1903936"(cellular response to sodium arsenite)|go:"GO:1904637"(cellular response to ionomycin)|go:"GO:1990869"(cellular response to chemokine)|go:"GO:2000320"(negative regulation of T-helper 17 cell differentiation)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|go:"GO:2000627"(positive regulation of miRNA catabolic process)|interpro:IPR021869|interpro:IPR040546|interpro:IPR040757|rcsb pdb:3V32|rcsb pdb:3V33|rcsb pdb:3V34|go:"GO:1900745"(positive regulation of p38MAPK cascade)|entrezgene/locuslink:80149(identity)	-	crc64:F3DBABE6AD3C7F3C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:etuSSgFGQOcgxPDexEXUqQg6H5s559292	rogid:3FqqH/XrYjHaa5oJpPXvfYwHKCQ9606	intact-crc:626A37107A3892CC|rigid:9PZ5wbTppPaR8VCtVhxWGZzUepo	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P53829	uniprotkb:Q15427	intact:EBI-28306|uniprotkb:D6W0Q5|ensemblfungi:YNL288W	intact:EBI-348469|ensembl:ENSP00000271628|intact:EBI-1047735|uniprotkb:Q5SZ63	psi-mi:caf40_yeast(display_long)|uniprotkb:YNL288W(locus name)|uniprotkb:N0540(orf name)|uniprotkb:40 kDa CCR4-associated factor(gene name synonym)|uniprotkb:CAF40(gene name)|psi-mi:CAF40(display_short)	psi-mi:sf3b4_human(display_long)|uniprotkb:SF3B4(gene name)|psi-mi:SF3B4(display_short)|uniprotkb:SAP49(gene name synonym)|uniprotkb:Spliceosome-associated protein 49(gene name synonym)|uniprotkb:Pre-mRNA-splicing factor SF3b 49 kDa subunit(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11544140|imex:IM-24995-2298	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014111.1|sgd:S000005232|dip:DIP-1995N|mint:P53829|ensemblfungi:YNL288W(gene)|ensemblfungi:YNL288W_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR007216(Cell differentiation, Rcd1-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:4CV5|sgd:YNL288W(identity)	refseq:NP_005841.1|ensembl:ENSG00000143368(gene)|ensembl:ENST00000271628(transcript)|rcsb pdb:6QX9|rcsb pdb:6Y53|rcsb pdb:6Y5Q|rcsb pdb:7ABG|rcsb pdb:7ABH|rcsb pdb:7ABI|rcsb pdb:7DVQ|reactome:R-HSA-72163|reactome:R-HSA-72165|rcsb pdb:6AHD|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:1990935"(splicing factor binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034158|go:"GO:0000375"(RNA splicing, via transesterification reactions)|interpro:IPR034159|interpro:IPR035979|mint:Q15427|rcsb pdb:1X5T|rcsb pdb:5GVQ|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|entrezgene/locuslink:10262(identity)	-	crc64:F3DBABE6AD3C7F3C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:etuSSgFGQOcgxPDexEXUqQg6H5s559292	rogid:Jgy6WmBFKkphpZLLte2GgsagUVI9606	intact-crc:34056A3077891303|rigid:dEnI/usfnIkEGrMpac3rNG74SFw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P53829	uniprotkb:P53992	intact:EBI-28306|uniprotkb:D6W0Q5|ensemblfungi:YNL288W	intact:EBI-81134|uniprotkb:Q8WV25|ensembl:ENSP00000321845|ensembl:ENSP00000343405|uniprotkb:B4DZT4	psi-mi:caf40_yeast(display_long)|uniprotkb:YNL288W(locus name)|uniprotkb:N0540(orf name)|uniprotkb:40 kDa CCR4-associated factor(gene name synonym)|uniprotkb:CAF40(gene name)|psi-mi:CAF40(display_short)	psi-mi:sc24c_human(display_long)|uniprotkb:SEC24C(gene name)|psi-mi:SEC24C(display_short)|uniprotkb:KIAA0079(gene name synonym)|uniprotkb:SEC24-related protein C(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11544131|imex:IM-24995-2297	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014111.1|sgd:S000005232|dip:DIP-1995N|mint:P53829|ensemblfungi:YNL288W(gene)|ensemblfungi:YNL288W_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR007216(Cell differentiation, Rcd1-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:4CV5|sgd:YNL288W(identity)	go:"GO:0090110"(COPII-coated vesicle cargo loading)|go:"GO:0070971"(endoplasmic reticulum exit site)|interpro:IPR006895(Zinc finger, Sec23/Sec24-type)|interpro:IPR006896(Sec23/Sec24 trunk region)|interpro:IPR006900(Sec23/Sec24 helical region)|interpro:IPR007123(Gelsolin region)|interpro:IPR012990(Sec23/Sec24 beta-sandwich)|interpro:IPR029006|interpro:IPR036174|interpro:IPR036175|interpro:IPR036180|interpro:IPR036465|interpro:IPR041742|mint:P53992|rcsb pdb:3EH2|rcsb pdb:6PU1|reactome:R-HSA-1655829|reactome:R-HSA-204005|reactome:R-HSA-2132295|reactome:R-HSA-983170|reactome:R-HSA-5694530|ensembl:ENSG00000176986(gene)|ensembl:ENST00000339365(transcript)|ensembl:ENST00000345254(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0008270"(zinc ion binding)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0030127"(COPII vesicle coat)|refseq:NP_004913.2|refseq:NP_940999.1|dip:DIP-30981N|entrezgene/locuslink:9632(identity)	-	crc64:F3DBABE6AD3C7F3C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:etuSSgFGQOcgxPDexEXUqQg6H5s559292	rogid:kOKJkIWFOlIpRFLj5JshAGqAg6s9606	intact-crc:7F8767BF82EAC5AE|rigid:P4fg5s32kxj2U9SlU+cnA9lU0nE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P42575	uniprotkb:P53829	intact:EBI-520342|ensembl:ENSP00000312664|uniprotkb:P42576|uniprotkb:D3DXD6|uniprotkb:Q59F21|uniprotkb:Q7KZL6|uniprotkb:Q86UJ3|uniprotkb:Q9BUP7|uniprotkb:Q9BZK9|uniprotkb:A8K5F9|uniprotkb:E9PDN0|uniprotkb:Q9BZL0	intact:EBI-28306|uniprotkb:D6W0Q5|ensemblfungi:YNL288W	psi-mi:casp2_human(display_long)|uniprotkb:Protease ICH-1(gene name synonym)|uniprotkb:Neural precursor cell expressed developmentally down-regulated protein 2(gene name synonym)|uniprotkb:CASP2(gene name)|psi-mi:CASP2(display_short)|uniprotkb:ICH1(gene name synonym)|uniprotkb:NEDD2(gene name synonym)	psi-mi:caf40_yeast(display_long)|uniprotkb:YNL288W(locus name)|uniprotkb:N0540(orf name)|uniprotkb:40 kDa CCR4-associated factor(gene name synonym)|uniprotkb:CAF40(gene name)|psi-mi:CAF40(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11544122|imex:IM-24995-2296	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000106144(gene)|ensembl:ENST00000310447(transcript)|go:"GO:0001554"(luteolysis)|go:"GO:0003407"(neural retina development)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0007420"(brain development)|go:"GO:0007568"(aging)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0016020"(membrane)|go:"GO:0016485"(protein processing)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0035234"(ectopic germ cell programmed cell death)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0097153"(cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0097192"(extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:0097194"(execution phase of apoptosis)|go:"GO:0097199"(cysteine-type endopeptidase activity involved in apoptotic signaling pathway)|go:"GO:0097200"(cysteine-type endopeptidase activity involved in execution phase of apoptosis)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR001309(Peptidase C14, ICE, catalytic subunit p20)|interpro:IPR001315(Caspase Recruitment)|interpro:IPR002138(Peptidase C14, caspase non-catalytic subunit p10)|interpro:IPR002398(Peptidase C14, caspase precursor p45)|interpro:IPR011029(DEATH-like)|interpro:IPR015917(Peptidase C14, caspase precursor p45, core)|interpro:IPR016129(Peptidase C14, ICE, catalytic subunit p20, active site)|interpro:IPR029030|interpro:IPR033139|interpro:IPR035702|rcsb pdb:1PYO|rcsb pdb:2P2C|rcsb pdb:3R5J|rcsb pdb:3R6G|rcsb pdb:3R6L|rcsb pdb:3R7B|rcsb pdb:3R7N|refseq:NP_001215.1|refseq:NP_116764.2|refseq:NP_116765.2|rcsb pdb:3R7S|rcsb pdb:3RJM|rcsb pdb:6GKF|rcsb pdb:6GKG|rcsb pdb:6S9K|rcsb pdb:6SAD|rcsb pdb:6Y8B|rcsb pdb:6Y8D|reactome:R-HSA-168638|reactome:R-HSA-205025|reactome:R-HSA-6803207|entrezgene/locuslink:835(identity)	refseq:NP_014111.1|sgd:S000005232|dip:DIP-1995N|mint:P53829|ensemblfungi:YNL288W(gene)|ensemblfungi:YNL288W_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR007216(Cell differentiation, Rcd1-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:4CV5|sgd:YNL288W(identity)	-	-	crc64:F3DBABE6AD3C7F3C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:3WFvmDoYbW3J84Yd9RVGAOcR8ig9606	rogid:etuSSgFGQOcgxPDexEXUqQg6H5s559292	intact-crc:A87C4ADC05600FC3|rigid:Ygl8eQbfjHfmfuTNoP01Z9Rqj1U	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P53829	uniprotkb:P37198	intact:EBI-28306|uniprotkb:D6W0Q5|ensemblfungi:YNL288W	intact:EBI-347978|intact:EBI-28983799|ensembl:ENSP00000305503|ensembl:ENSP00000407331|ensembl:ENSP00000471191|ensembl:ENSP00000473192|uniprotkb:Q6GTM2|uniprotkb:Q503A4|uniprotkb:Q96C43|uniprotkb:Q9NSL1|uniprotkb:B3KWU5	psi-mi:caf40_yeast(display_long)|uniprotkb:YNL288W(locus name)|uniprotkb:N0540(orf name)|uniprotkb:40 kDa CCR4-associated factor(gene name synonym)|uniprotkb:CAF40(gene name)|psi-mi:CAF40(display_short)	psi-mi:nup62_human(display_long)|uniprotkb:NUP62(gene name)|psi-mi:NUP62(display_short)|uniprotkb:62 kDa nucleoporin(gene name synonym)|uniprotkb:Nucleoporin Nup62(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11544113|imex:IM-24995-2295	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014111.1|sgd:S000005232|dip:DIP-1995N|mint:P53829|ensemblfungi:YNL288W(gene)|ensemblfungi:YNL288W_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR007216(Cell differentiation, Rcd1-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:4CV5|sgd:YNL288W(identity)	refseq:NP_714941.1|ensembl:ENSG00000213024(gene)|ensembl:ENST00000352066(transcript)|ensembl:ENST00000422090(transcript)|ensembl:ENST00000596217(transcript)|ensembl:ENST00000597029(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005642"(annulate lamellae)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007100"(mitotic centrosome separation)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007569"(cell aging)|go:"GO:0008219"(cell death)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0003682"(chromatin binding)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0019894"(kinesin binding)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042306"(regulation of protein import into nucleus)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043069"(negative regulation of programmed cell death)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045742"(positive regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046578"(regulation of Ras protein signal transduction)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0046601"(positive regulation of centriole replication)|go:"GO:0051028"(mRNA transport)|go:"GO:0051425"(PTB domain binding)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0072686"(mitotic spindle)|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|go:"GO:0090543"(Flemming body)|go:"GO:0098534"(centriole assembly)|go:"GO:1903438"(positive regulation of mitotic cytokinetic process)|go:"GO:1904781"(positive regulation of protein localization to centrosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR007758(Nucleoporin, Nsp1-like, C-terminal)|interpro:IPR026010|interpro:IPR033072|mint:P37198|rcsb pdb:2H4D|rcsb pdb:5IJN|rcsb pdb:5IJO|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|refseq:NP_714940.1|refseq:NP_001180286.1|refseq:NP_036478.2|refseq:NP_057637.2|ensembl:ENSP00000305503|ensembl:ENSP00000407331|ensembl:ENSP00000471191|ensembl:ENSP00000473192|dip:DIP-29749N|entrezgene/locuslink:23636(identity)	-	crc64:F3DBABE6AD3C7F3C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:etuSSgFGQOcgxPDexEXUqQg6H5s559292	rogid:v7mvKvTtVEnLMwcpUZIcdAzge009606	intact-crc:D7CEDD79F86AE47C|rigid:0qAntt6PSBiPdBfSNgOEoe/3fxI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32321	uniprotkb:P53829	intact:EBI-739870|uniprotkb:Q9BVD8|uniprotkb:B2R836|uniprotkb:Q5M7Z8|uniprotkb:D3DP49|uniprotkb:D3DP50|ensembl:ENSP00000398194|ensembl:ENSP00000424017	intact:EBI-28306|uniprotkb:D6W0Q5|ensemblfungi:YNL288W	psi-mi:dctd_human(display_long)|uniprotkb:DCTD(gene name)|psi-mi:DCTD(display_short)|uniprotkb:dCMP deaminase(gene name synonym)	psi-mi:caf40_yeast(display_long)|uniprotkb:YNL288W(locus name)|uniprotkb:N0540(orf name)|uniprotkb:40 kDa CCR4-associated factor(gene name synonym)|uniprotkb:CAF40(gene name)|psi-mi:CAF40(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11544104|imex:IM-24995-2294	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001012750.1|refseq:NP_001912.2|ensembl:ENSG00000129187(gene)|ensembl:ENST00000438320(transcript)|ensembl:ENST00000510370(transcript)|go:"GO:0004132"(dCMP deaminase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006220"(pyrimidine nucleotide metabolic process)|go:"GO:0006226"(dUMP biosynthetic process)|go:"GO:0006231"(dTMP biosynthetic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR002125(CMP/dCMP deaminase, zinc-binding)|interpro:IPR015517(Cytidine deaminase)|interpro:IPR016192(APOBEC/CMP deaminase, zinc-binding)|interpro:IPR016193(Cytidine deaminase-like)|interpro:IPR016473(dCMP deaminase)|interpro:IPR035105|mint:P32321|rcsb pdb:2W4L|reactome:R-HSA-499943|refseq:XP_005262836.1|refseq:XP_005262837.1|refseq:XP_011529976.1|refseq:XP_016863305.1|refseq:XP_016863306.1|refseq:XP_016863307.1|refseq:XP_016863308.1|refseq:XP_016863309.1|refseq:XP_016863310.1|refseq:XP_016863311.1|entrezgene/locuslink:1635(identity)	refseq:NP_014111.1|sgd:S000005232|dip:DIP-1995N|mint:P53829|ensemblfungi:YNL288W(gene)|ensemblfungi:YNL288W_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR007216(Cell differentiation, Rcd1-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:4CV5|sgd:YNL288W(identity)	-	-	crc64:F3DBABE6AD3C7F3C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:lU3gEi7XdIJbuPlMkForbVKEOyY9606	rogid:etuSSgFGQOcgxPDexEXUqQg6H5s559292	intact-crc:D357AF3E3C58E59E|rigid:AxSpZw9n6xa4SlD4PHm1ExQ6IVs	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P53829	uniprotkb:Q9BQY4	intact:EBI-28306|uniprotkb:D6W0Q5|ensemblfungi:YNL288W	intact:EBI-372094|uniprotkb:Q9BR00|ensembl:ENSP00000360441	psi-mi:caf40_yeast(display_long)|uniprotkb:YNL288W(locus name)|uniprotkb:N0540(orf name)|uniprotkb:40 kDa CCR4-associated factor(gene name synonym)|uniprotkb:CAF40(gene name)|psi-mi:CAF40(display_short)	psi-mi:rhxf2_human(display_long)|uniprotkb:RHOXF2(gene name)|psi-mi:RHOXF2(display_short)|uniprotkb:THG1(gene name synonym)|uniprotkb:Paired-like homeobox protein PEPP-2(gene name synonym)|uniprotkb:Testis homeobox gene 1(gene name synonym)|uniprotkb:PEPP2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11544185|imex:IM-24995-2303	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014111.1|sgd:S000005232|dip:DIP-1995N|mint:P53829|ensemblfungi:YNL288W(gene)|ensemblfungi:YNL288W_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR007216(Cell differentiation, Rcd1-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:4CV5|sgd:YNL288W(identity)	refseq:NP_115887.1|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0042802"(identical protein binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|ensembl:ENSG00000131721(gene)|ensembl:ENST00000371388(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|entrezgene/locuslink:84528(identity)	-	crc64:F3DBABE6AD3C7F3C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:etuSSgFGQOcgxPDexEXUqQg6H5s559292	rogid:shpgPqf80gNt+gFDv1K+827ELUQ9606	intact-crc:E2B6B3EB33262809|rigid:cr3njtD9XOdDhbJXnJOvYX9vN0Q	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96IK5	uniprotkb:P53829	intact:EBI-2548508|ensembl:ENSP00000282570|uniprotkb:Q9H826|uniprotkb:Q9H8V7|uniprotkb:Q9H927	intact:EBI-28306|uniprotkb:D6W0Q5|ensemblfungi:YNL288W	psi-mi:gmcl1_human(display_long)|uniprotkb:GMCL1(gene name)|psi-mi:GMCL1(display_short)|uniprotkb:GCL(gene name synonym)|uniprotkb:BTBD13(gene name synonym)|uniprotkb:SPATA29(gene name synonym)|uniprotkb:Spermatogenesis-associated protein 29(gene name synonym)	psi-mi:caf40_yeast(display_long)|uniprotkb:YNL288W(locus name)|uniprotkb:N0540(orf name)|uniprotkb:40 kDa CCR4-associated factor(gene name synonym)|uniprotkb:CAF40(gene name)|psi-mi:CAF40(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11544176|imex:IM-24995-2302	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000087338(gene)|ensembl:ENST00000282570(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0007281"(germ cell development)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016363"(nuclear matrix)|go:"GO:0042802"(identical protein binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR043380|refseq:NP_848526.1|entrezgene/locuslink:64395(identity)	refseq:NP_014111.1|sgd:S000005232|dip:DIP-1995N|mint:P53829|ensemblfungi:YNL288W(gene)|ensemblfungi:YNL288W_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR007216(Cell differentiation, Rcd1-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:4CV5|sgd:YNL288W(identity)	-	-	crc64:F3DBABE6AD3C7F3C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:ED8yqySVu7BWxpw3DUSNBZSQWrk9606	rogid:etuSSgFGQOcgxPDexEXUqQg6H5s559292	intact-crc:B81A9F3EC584EF45|rigid:9+9FWWtCkFBRiYY6flmnSQGpyz4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P53829	uniprotkb:Q8WWB3	intact:EBI-28306|uniprotkb:D6W0Q5|ensemblfungi:YNL288W	intact:EBI-740680|ensembl:ENSP00000361276|ensembl:ENSP00000361278|ensembl:ENSP00000402890|uniprotkb:Q5QP03|uniprotkb:Q5QP04|uniprotkb:Q6WNP4|uniprotkb:Q6ZU87|uniprotkb:A8K927	psi-mi:caf40_yeast(display_long)|uniprotkb:YNL288W(locus name)|uniprotkb:N0540(orf name)|uniprotkb:40 kDa CCR4-associated factor(gene name synonym)|uniprotkb:CAF40(gene name)|psi-mi:CAF40(display_short)	psi-mi:dydc1_human(display_long)|uniprotkb:DYDC1(gene name)|psi-mi:DYDC1(display_short)|uniprotkb:DPY30D1(gene name synonym)|uniprotkb:RSD9(orf name)|uniprotkb:RSD-9(orf name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11544167|imex:IM-24995-2301	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014111.1|sgd:S000005232|dip:DIP-1995N|mint:P53829|ensemblfungi:YNL288W(gene)|ensemblfungi:YNL288W_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR007216(Cell differentiation, Rcd1-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:4CV5|sgd:YNL288W(identity)	refseq:NP_620167.1|ensembl:ENSG00000170788(gene)|ensembl:ENST00000372202(transcript)|ensembl:ENST00000372204(transcript)|ensembl:ENST00000421924(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0006348"|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|interpro:IPR007858(Dpy-30)|interpro:IPR037856|refseq:XP_011537636.1|refseq:XP_011537637.1|refseq:NP_001255982.1|refseq:XP_005269606.1|refseq:XP_005269607.1|entrezgene/locuslink:143241(identity)	-	crc64:F3DBABE6AD3C7F3C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:etuSSgFGQOcgxPDexEXUqQg6H5s559292	rogid:W6GUazYFXZGHGijUBpAJ5GiRuXA9606	intact-crc:7CAE832B4E537932|rigid:3uApgK1+ckwOYgj1xkBsy5HP/P4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8NDC0	uniprotkb:P53829	intact:EBI-741424|uniprotkb:Q96BG5|ensembl:ENSP00000378851|ensembl:ENSP00000481882|uniprotkb:B2RDD8	intact:EBI-28306|uniprotkb:D6W0Q5|ensemblfungi:YNL288W	psi-mi:missl_human(display_long)|uniprotkb:C14orf32(gene name synonym)|uniprotkb:Mitogen-activated protein kinase 1-interacting protein 1-like(gene name synonym)|uniprotkb:MAPK1IP1L(gene name)|psi-mi:MAPK1IP1L(display_short)	psi-mi:caf40_yeast(display_long)|uniprotkb:YNL288W(locus name)|uniprotkb:N0540(orf name)|uniprotkb:40 kDa CCR4-associated factor(gene name synonym)|uniprotkb:CAF40(gene name)|psi-mi:CAF40(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11544158|imex:IM-24995-2300	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_653179.1|ensembl:ENSG00000168175(gene)|ensembl:ENST00000395468(transcript)|ensembl:ENST00000622254(transcript)|interpro:IPR031653|entrezgene/locuslink:93487(identity)	refseq:NP_014111.1|sgd:S000005232|dip:DIP-1995N|mint:P53829|ensemblfungi:YNL288W(gene)|ensemblfungi:YNL288W_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR007216(Cell differentiation, Rcd1-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:4CV5|sgd:YNL288W(identity)	-	-	crc64:F3DBABE6AD3C7F3C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:CX220vB2TjggPEso5CHNUVzl79g9606	rogid:etuSSgFGQOcgxPDexEXUqQg6H5s559292	intact-crc:EF091BA6F27ADEC5|rigid:omG8K9P74/OnVxCpgI4sniKFvzE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P53829	uniprotkb:Q9BW62	intact:EBI-28306|uniprotkb:D6W0Q5|ensemblfungi:YNL288W	intact:EBI-743591|uniprotkb:A8K5X4|ensembl:ENSP00000369989|ensembl:ENSP00000369991	psi-mi:caf40_yeast(display_long)|uniprotkb:YNL288W(locus name)|uniprotkb:N0540(orf name)|uniprotkb:40 kDa CCR4-associated factor(gene name synonym)|uniprotkb:CAF40(gene name)|psi-mi:CAF40(display_short)	psi-mi:katl1_human(display_long)|uniprotkb:p60 katanin-like 1(gene name synonym)|uniprotkb:KATNAL1(gene name)|psi-mi:KATNAL1(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11544194|imex:IM-24995-2304	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014111.1|sgd:S000005232|dip:DIP-1995N|mint:P53829|ensemblfungi:YNL288W(gene)|ensemblfungi:YNL288W_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR007216(Cell differentiation, Rcd1-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:4CV5|sgd:YNL288W(identity)	refseq:NP_001014402.1|refseq:NP_115492.1|refseq:XP_005266631.1|ensembl:ENSG00000102781(gene)|ensembl:ENST00000380615(transcript)|ensembl:ENST00000380617(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005874"(microtubule)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008017"(microtubule binding)|go:"GO:0008568"(microtubule-severing ATPase activity)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016853"(isomerase activity)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0042802"(identical protein binding)|go:"GO:0051013"(microtubule severing)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR027417|interpro:IPR028594|interpro:IPR028596|interpro:IPR041569|rcsb pdb:6B5C|entrezgene/locuslink:84056(identity)	-	crc64:F3DBABE6AD3C7F3C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:etuSSgFGQOcgxPDexEXUqQg6H5s559292	rogid:Usi4KXsvZnNfMOGuWVSz4mfrTaE9606	intact-crc:D9F45B497BE8AC7C|rigid:iztkWzEAJT7OQQ9kuB+uGAcdOOs	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9H9H4	uniprotkb:P53829	intact:EBI-4400866|intact:EBI-28975719|ensembl:ENSP00000267202	intact:EBI-28306|uniprotkb:D6W0Q5|ensemblfungi:YNL288W	psi-mi:vp37b_human(display_long)|uniprotkb:VPS37B(gene name)|psi-mi:VPS37B(display_short)|uniprotkb:ESCRT-I complex subunit VPS37B(gene name synonym)	psi-mi:caf40_yeast(display_long)|uniprotkb:YNL288W(locus name)|uniprotkb:N0540(orf name)|uniprotkb:40 kDa CCR4-associated factor(gene name synonym)|uniprotkb:CAF40(gene name)|psi-mi:CAF40(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11544203|imex:IM-24995-2305	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000267202|refseq:NP_078943.1|ensembl:ENSG00000139722(gene)|ensembl:ENST00000267202(transcript)|go:"GO:0000813"(ESCRT I complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0010008"(endosome membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0030496"(midbody)|go:"GO:0031902"(late endosome membrane)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1902188"(obsolete positive regulation of viral release from host cell)|go:"GO:1903774"(positive regulation of viral budding via host ESCRT complex)|interpro:IPR009851(Modifier of rudimentary, Modr)|interpro:IPR029012|interpro:IPR037202|mint:Q9H9H4|rcsb pdb:6VME|reactome:R-HSA-162588|reactome:R-HSA-174490|reactome:R-HSA-917729|reactome:R-HSA-9610379|reactome:R-HSA-9615710|entrezgene/locuslink:79720(identity)	refseq:NP_014111.1|sgd:S000005232|dip:DIP-1995N|mint:P53829|ensemblfungi:YNL288W(gene)|ensemblfungi:YNL288W_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR007216(Cell differentiation, Rcd1-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:4CV5|sgd:YNL288W(identity)	-	-	crc64:F3DBABE6AD3C7F3C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:dj398+zsegXf+gk9OiSeZAVlmqk9606	rogid:etuSSgFGQOcgxPDexEXUqQg6H5s559292	intact-crc:8D29F74AD5E37552|rigid:l24RfhSGwCw99FUchlCxB27/nQY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9NRG1	uniprotkb:P53829	intact:EBI-739759|uniprotkb:Q53HA7|uniprotkb:Q59EL9|uniprotkb:Q5VV18|uniprotkb:Q5VV20|uniprotkb:B7Z1Z3|ensembl:ENSP00000318602	intact:EBI-28306|uniprotkb:D6W0Q5|ensemblfungi:YNL288W	psi-mi:prdc1_human(display_long)|uniprotkb:PRTFDC1(gene name)|psi-mi:PRTFDC1(display_short)|uniprotkb:HHGP(gene name synonym)	psi-mi:caf40_yeast(display_long)|uniprotkb:YNL288W(locus name)|uniprotkb:N0540(orf name)|uniprotkb:40 kDa CCR4-associated factor(gene name synonym)|uniprotkb:CAF40(gene name)|psi-mi:CAF40(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11544212|imex:IM-24995-2306	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001269715.1|refseq:NP_064585.1|ensembl:ENSG00000099256(gene)|ensembl:ENST00000320152(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0006166"(purine ribonucleoside salvage)|go:"GO:0042803"(protein homodimerization activity)|interpro:IPR000836(Phosphoribosyltransferase)|interpro:IPR005904(Hypoxanthine phosphoribosyl transferase)|interpro:IPR029057|rcsb pdb:2JBH|entrezgene/locuslink:56952(identity)	refseq:NP_014111.1|sgd:S000005232|dip:DIP-1995N|mint:P53829|ensemblfungi:YNL288W(gene)|ensemblfungi:YNL288W_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR007216(Cell differentiation, Rcd1-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:4CV5|sgd:YNL288W(identity)	-	-	crc64:F3DBABE6AD3C7F3C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:grTZnSalFILRSeeZBjM1mTtF0xo9606	rogid:etuSSgFGQOcgxPDexEXUqQg6H5s559292	intact-crc:809D12026F147671|rigid:djKy/pJTqauRfpWeChUlWsatnr4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P53829	uniprotkb:Q9NVV9	intact:EBI-28306|uniprotkb:D6W0Q5|ensemblfungi:YNL288W	intact:EBI-741515|uniprotkb:Q53FQ1|uniprotkb:Q6IA99|ensembl:ENSP00000254250|uniprotkb:A6NCB6|uniprotkb:D3DSY5|uniprotkb:H9KV49	psi-mi:caf40_yeast(display_long)|uniprotkb:YNL288W(locus name)|uniprotkb:N0540(orf name)|uniprotkb:40 kDa CCR4-associated factor(gene name synonym)|uniprotkb:CAF40(gene name)|psi-mi:CAF40(display_short)	psi-mi:thap1_human(display_long)|uniprotkb:THAP1(gene name)|psi-mi:THAP1(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11544221|imex:IM-24995-2307	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014111.1|sgd:S000005232|dip:DIP-1995N|mint:P53829|ensemblfungi:YNL288W(gene)|ensemblfungi:YNL288W_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR007216(Cell differentiation, Rcd1-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:4CV5|sgd:YNL288W(identity)	refseq:NP_060575.1|ensembl:ENSG00000131931(gene)|ensembl:ENST00000254250(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001650"(fibrillar center)|go:"GO:0001935"(endothelial cell proliferation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007049"(cell cycle)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016605"(PML body)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR006612(Zinc finger, C2CH-type)|interpro:IPR026516|interpro:IPR038441|mint:Q9NVV9|rcsb pdb:2JTG|rcsb pdb:2KO0|rcsb pdb:2L1G|refseq:NP_945354.1|entrezgene/locuslink:55145(identity)	-	crc64:F3DBABE6AD3C7F3C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:etuSSgFGQOcgxPDexEXUqQg6H5s559292	rogid:/KO90pu5tBnIVq9SMx1JYPXFCEQ9606	intact-crc:529911BADDE41FBD|rigid:EOb1ad62YBbD7PDY8Bl/GbqC7i0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9Y2J4	uniprotkb:P53829	intact:EBI-746752|intact:EBI-28986657|ensembl:ENSP00000409999|uniprotkb:Q53EP1|uniprotkb:Q96F99|uniprotkb:Q9UKB4|uniprotkb:A8K6F1|uniprotkb:B7Z5Q1|uniprotkb:E9PHW3	intact:EBI-28306|uniprotkb:D6W0Q5|ensemblfungi:YNL288W	psi-mi:amol2_human(display_long)|uniprotkb:Leman coiled-coil protein(gene name synonym)|uniprotkb:AMOTL2(gene name)|psi-mi:AMOTL2(display_short)|uniprotkb:KIAA0989(gene name synonym)	psi-mi:caf40_yeast(display_long)|uniprotkb:YNL288W(locus name)|uniprotkb:N0540(orf name)|uniprotkb:40 kDa CCR4-associated factor(gene name synonym)|uniprotkb:CAF40(gene name)|psi-mi:CAF40(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11544230|imex:IM-24995-2308	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001265612.1|refseq:NP_001265614.1|ensembl:ENSG00000114019(gene)|refseq:XP_006713717.1|refseq:NP_057285.3|refseq:XP_011511183.1|ensembl:ENST00000422605(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0003365"(establishment of cell polarity involved in ameboidal cell migration)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0035329"(hippo signaling)|go:"GO:0055037"(recycling endosome)|interpro:IPR009114(Angiomotin)|interpro:IPR024646|mint:Q9Y2J4|reactome:R-HSA-2028269|refseq:XP_016862069.1|refseq:XP_016862070.1|refseq:XP_016862071.1|ensembl:ENST00000249883|ensembl:ENSP00000249883|ensembl:ENSP00000409999|ensembl:ENST00000513145|ensembl:ENSP00000425475|ensembl:ENST00000514516|ensembl:ENSP00000424765|dip:DIP-57510N|entrezgene/locuslink:51421(identity)	refseq:NP_014111.1|sgd:S000005232|dip:DIP-1995N|mint:P53829|ensemblfungi:YNL288W(gene)|ensemblfungi:YNL288W_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR007216(Cell differentiation, Rcd1-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:4CV5|sgd:YNL288W(identity)	-	-	crc64:F3DBABE6AD3C7F3C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:SHtKAcLLnTpSSLwVE7yQ1WECoZk9606	rogid:etuSSgFGQOcgxPDexEXUqQg6H5s559292	intact-crc:922ADAB9489929D4|rigid:wL97b/N7Zx3p3qCYb4ZACTiLgkw	false	sufficient binding region:314-779	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P53833	uniprotkb:O95273	intact:EBI-13638|uniprotkb:D6W0R2|ensemblfungi:YNL282W	intact:EBI-748961|uniprotkb:A8K3Q0|uniprotkb:A8K3U2|uniprotkb:Q6ZQN9|uniprotkb:Q7Z519|uniprotkb:Q8NBS7|uniprotkb:Q8NBY2|uniprotkb:Q9NS19|uniprotkb:Q9NYH3|uniprotkb:Q9UHX9|ensembl:ENSP00000300213	psi-mi:pop3_yeast(display_long)|uniprotkb:POP3(gene name)|psi-mi:POP3(display_short)|uniprotkb:YNL282W(locus name)|uniprotkb:N0586(orf name)|uniprotkb:RNA-processing protein POP3(gene name synonym)|uniprotkb:RNases MRP/P 22.6 kDa subunit(gene name synonym)	psi-mi:ccdb1_human(display_long)|uniprotkb:Grap2 and cyclin-D-interacting protein(gene name synonym)|uniprotkb:Human homolog of Maid(gene name synonym)|uniprotkb:CCNDBP1(gene name)|psi-mi:CCNDBP1(display_short)|uniprotkb:DIP1(gene name synonym)|uniprotkb:GCIP(gene name synonym)|uniprotkb:HHM(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11544241|imex:IM-24995-2309	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YNL282W(gene)|refseq:NP_014117.1|sgd:S000005226|ensemblfungi:YNL282W_mRNA(transcript)|go:"GO:0000172"(ribonuclease MRP complex)|go:"GO:0000294"(nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay)|go:"GO:0005634"(nucleus)|go:"GO:0005655"(nucleolar ribonuclease P complex)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0008033"(tRNA processing)|go:"GO:0034965"(intronic box C/D RNA processing)|go:"GO:0090502"(RNA phosphodiester bond hydrolysis, endonucleolytic)|interpro:IPR013241(RNase P, subunit Pop3)|rcsb pdb:6AGB|rcsb pdb:6AH3|rcsb pdb:7C79|rcsb pdb:7C7A|mint:P53833|dip:DIP-4997N|sgd:YNL282W(identity)	refseq:NP_036274.3|ensembl:ENSG00000166946(gene)|ensembl:ENST00000300213(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0016604"(nuclear body)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR026907|mint:O95273|rcsb pdb:3AY5|entrezgene/locuslink:23582(identity)	-	crc64:5091EE590BDBCBEA	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:t1z4FYhAJbd9swpeZ8/+rqxgKyk559292	rogid:Vi9aoFc+Mov6P3X6KGmsTxXqxvM9606	intact-crc:66C89365E4A473E1|rigid:c3J1i2AwKwN4hlWp3i+QGshpy4g	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96HR9	uniprotkb:P53845	intact:EBI-750345|uniprotkb:Q96LM0|uniprotkb:B2RE01|uniprotkb:A0A1L5BXV3|uniprotkb:D6W5Z0|ensembl:ENSP00000378861	intact:EBI-28230|uniprotkb:D6W0T0|ensemblfungi:YNL263C	psi-mi:reep6_human(display_long)|uniprotkb:Polyposis locus protein 1-like 1(gene name synonym)|uniprotkb:REEP6(gene name)|psi-mi:REEP6(display_short)|uniprotkb:C19orf32(gene name synonym)|uniprotkb:DP1L1(gene name synonym)	psi-mi:yif1_yeast(display_long)|uniprotkb:YNL263C(locus name)|uniprotkb:N0820(orf name)|uniprotkb:YIF1(gene name)|psi-mi:YIF1(display_short)|uniprotkb:YIP1-interacting factor 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11544259|imex:IM-24995-2311	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_612402.1|refseq:NP_001316485.1|ensembl:ENSG00000115255(gene)|ensembl:ENST00000395479(transcript)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030665"(clathrin-coated vesicle membrane)|go:"GO:0032386"(regulation of intracellular transport)|go:"GO:0050908"(detection of light stimulus involved in visual perception)|interpro:IPR004345(TB2/DP1 and HVA22 related protein)|mint:Q96HR9|reactome:R-HSA-381753|go:"GO:0005634"(nucleus)|entrezgene/locuslink:92840(identity)	refseq:NP_014136.1|sgd:S000005207|dip:DIP-1729N|ensemblfungi:YNL263C(gene)|ensemblfungi:YNL263C_mRNA(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0015031"(protein transport)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0030173"(integral component of Golgi membrane)|interpro:IPR005578(Hrf1)|sgd:YNL263C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2017/05/05	rogid:pB8AjjNTpmaaLJ8j7MCBM45UAHE9606	rogid:HEs4ZRFWRAkXinwmuLiWGpmUqsM559292	intact-crc:6D3017567980BE19|rigid:NrYeqeWFOpq/h3AvUoDJC6WdpbE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P53900	uniprotkb:A0A024R4Q5	intact:EBI-13246|uniprotkb:D6W130|ensemblfungi:YNL153C	intact:EBI-11527449	psi-mi:pfd4_yeast(display_long)|uniprotkb:GIM3(gene name)|psi-mi:GIM3(display_short)|uniprotkb:PFD4(gene name synonym)|uniprotkb:YNL153C(locus name)|uniprotkb:N1761(orf name)|uniprotkb:Genes involved in microtubule biogenesis protein 3(gene name synonym)|uniprotkb:Gim complex subunit 3(gene name synonym)	psi-mi:a0a024r4q5_human(display_long)|uniprotkb:hCG_20946(orf name)|uniprotkb:TFPT(gene name)|psi-mi:TFPT(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11544268|imex:IM-24995-2312	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014246.1|sgd:S000005097|mint:P53900|dip:DIP-3000N|ensemblfungi:YNL153C(gene)|ensemblfungi:YNL153C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:0015631"(tubulin binding)|go:"GO:0016272"(prefoldin complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0071629"(cytoplasm protein quality control by the ubiquitin-proteasome system)|interpro:IPR002777(Prefoldin beta-like)|interpro:IPR009053(Prefoldin)|interpro:IPR016661(Prefoldin, subunit 4)|sgd:YNL153C(identity)	refseq:NP_037474.1|interpro:IPR033555|go:"GO:0005654"(nucleoplasm)|go:"GO:0006915"(apoptotic process)|entrezgene/locuslink:29844(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:TdRDErsc5xwqaEqpI4SSCW0sCsg559292	rogid:juI/3gZemjc0hnXDJ9J+bIQ9pBw9606	intact-crc:B3E247B4B43A7D78|rigid:1lexydUUIaNmP+up2nXxHIJg2AE	false	-	sufficient binding region:10-253	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P43365	uniprotkb:P53900	intact:EBI-749530|uniprotkb:Q9NSD3|intact:EBI-10178394|uniprotkb:Q6FHH8|ensembl:ENSP00000350592|ensembl:ENSP00000377447|ensembl:ENSP00000377478	intact:EBI-13246|uniprotkb:D6W130|ensemblfungi:YNL153C	psi-mi:magac_human(display_long)|uniprotkb:MAGE-12 antigen(gene name synonym)|uniprotkb:MAGE12F antigen(gene name synonym)|uniprotkb:Cancer/testis antigen 1.12(gene name synonym)|uniprotkb:MAGEA12(gene name)|psi-mi:MAGEA12(display_short)|uniprotkb:MAGE12(gene name synonym)	psi-mi:pfd4_yeast(display_long)|uniprotkb:GIM3(gene name)|psi-mi:GIM3(display_short)|uniprotkb:PFD4(gene name synonym)|uniprotkb:YNL153C(locus name)|uniprotkb:N1761(orf name)|uniprotkb:Genes involved in microtubule biogenesis protein 3(gene name synonym)|uniprotkb:Gim complex subunit 3(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11544279|imex:IM-24995-2313	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001159858.1|refseq:NP_001159859.1|refseq:NP_005358.2|ensembl:ENSG00000213401(gene)|ensembl:ENST00000357916(transcript)|ensembl:ENST00000393869(transcript)|ensembl:ENST00000393900(transcript)|interpro:IPR002190(MAGE protein)|interpro:IPR021072|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|entrezgene/locuslink:4111(identity)	refseq:NP_014246.1|sgd:S000005097|mint:P53900|dip:DIP-3000N|ensemblfungi:YNL153C(gene)|ensemblfungi:YNL153C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:0015631"(tubulin binding)|go:"GO:0016272"(prefoldin complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0071629"(cytoplasm protein quality control by the ubiquitin-proteasome system)|interpro:IPR002777(Prefoldin beta-like)|interpro:IPR009053(Prefoldin)|interpro:IPR016661(Prefoldin, subunit 4)|sgd:YNL153C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:3/Jxz2VsFOb67RWqWj3xbTrw3s49606	rogid:TdRDErsc5xwqaEqpI4SSCW0sCsg559292	intact-crc:C76744AF0626EF9E|rigid:EPAg9IMHONr/O35Snf2Pkb3nT7k	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q15041	uniprotkb:P53845	intact:EBI-714543|ensembl:ENSP00000306788|uniprotkb:B7Z6S5|uniprotkb:B7Z791|uniprotkb:F5GXP4	intact:EBI-28230|uniprotkb:D6W0T0|ensemblfungi:YNL263C	psi-mi:ar6p1_human(display_long)|uniprotkb:ARL6IP(gene name synonym)|uniprotkb:ARL6IP1(gene name)|psi-mi:ARL6IP1(display_short)|uniprotkb:KIAA0069(gene name synonym)|uniprotkb:ARMER(gene name synonym)|uniprotkb:Apoptotic regulator in the membrane of the endoplasmic reticulum(gene name synonym)	psi-mi:yif1_yeast(display_long)|uniprotkb:YNL263C(locus name)|uniprotkb:N0820(orf name)|uniprotkb:YIF1(gene name)|psi-mi:YIF1(display_short)|uniprotkb:YIP1-interacting factor 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11544250|imex:IM-24995-2310	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055976.1|ensembl:ENSG00000170540(gene)|ensembl:ENST00000304414(transcript)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006613"(cotranslational protein targeting to membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0071787"(endoplasmic reticulum tubular network formation)|go:"GO:1903371"(regulation of endoplasmic reticulum tubular network organization)|go:"GO:1990809"(endoplasmic reticulum tubular network membrane organization)|interpro:IPR033301|mint:Q15041|go:"GO:0002038"(positive regulation of L-glutamate import across plasma membrane)|refseq:NP_001300787.1|entrezgene/locuslink:23204(identity)	refseq:NP_014136.1|sgd:S000005207|dip:DIP-1729N|ensemblfungi:YNL263C(gene)|ensemblfungi:YNL263C_mRNA(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0015031"(protein transport)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0030173"(integral component of Golgi membrane)|interpro:IPR005578(Hrf1)|sgd:YNL263C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:3fjkoyvUx25po7xsPcXgpjEeLJg9606	rogid:HEs4ZRFWRAkXinwmuLiWGpmUqsM559292	intact-crc:23CF382A3F1F9D43|rigid:8t8aGnhVCEYy1sCcPsi+mIFoPcw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12800	uniprotkb:P53900	intact:EBI-717422|uniprotkb:Q12801|uniprotkb:Q9UD77|uniprotkb:A8K5E9|uniprotkb:Q9UD75|ensembl:ENSP00000257915	intact:EBI-13246|uniprotkb:D6W130|ensemblfungi:YNL153C	psi-mi:tfcp2_human(display_long)|uniprotkb:Transcription factor LSF(gene name synonym)|uniprotkb:SAA3 enhancer factor(gene name synonym)|uniprotkb:TFCP2(gene name)|psi-mi:TFCP2(display_short)|uniprotkb:LSF(gene name synonym)|uniprotkb:SEF(gene name synonym)	psi-mi:pfd4_yeast(display_long)|uniprotkb:GIM3(gene name)|psi-mi:GIM3(display_short)|uniprotkb:PFD4(gene name synonym)|uniprotkb:YNL153C(locus name)|uniprotkb:N1761(orf name)|uniprotkb:Genes involved in microtubule biogenesis protein 3(gene name synonym)|uniprotkb:Gim complex subunit 3(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11544288|imex:IM-24995-2314	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001166923.1|refseq:NP_001166924.1|refseq:NP_005644.2|ensembl:ENSG00000135457(gene)|ensembl:ENST00000257915(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR007604(CP2 transcription factor)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR037599|interpro:IPR041418|mint:Q12800|entrezgene/locuslink:7024(identity)	refseq:NP_014246.1|sgd:S000005097|mint:P53900|dip:DIP-3000N|ensemblfungi:YNL153C(gene)|ensemblfungi:YNL153C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:0015631"(tubulin binding)|go:"GO:0016272"(prefoldin complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0071629"(cytoplasm protein quality control by the ubiquitin-proteasome system)|interpro:IPR002777(Prefoldin beta-like)|interpro:IPR009053(Prefoldin)|interpro:IPR016661(Prefoldin, subunit 4)|sgd:YNL153C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:M7mQ08NDYxuawmUEKRgjSdIr+Og9606	rogid:TdRDErsc5xwqaEqpI4SSCW0sCsg559292	intact-crc:9F1CBF873F952A0C|rigid:4kETE+1FpGLf+uZfabdDMW6BF5Y	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P53906	uniprotkb:Q8N6L0	intact:EBI-28943|ensemblfungi:YNL146W|uniprotkb:D6W137	intact:EBI-749265|uniprotkb:Q96MC3|ensembl:ENSP00000404220	psi-mi:yno6_yeast(display_long)|uniprotkb:N1203(orf name)|uniprotkb:N1785(orf name)|uniprotkb:YNL146W(locus name)	psi-mi:kash5_human(display_long)|uniprotkb:KASH5(gene name)|psi-mi:KASH5(display_short)|uniprotkb:CCDC155(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 155(gene name synonym)|uniprotkb:KASH domain-containing protein 5(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11544297|imex:IM-24995-2315	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005090|ensemblfungi:YNL146W(gene)|refseq:NP_014253.3|dip:DIP-8009N|ensemblfungi:YNL146W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|sgd:YNL146W(identity)	refseq:NP_653289.3|ensembl:ENSG00000161609(gene)|ensembl:ENST00000447857(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034397"(telomere localization)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051225"(spindle assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0090172"(microtubule cytoskeleton organization involved in homologous chromosome segregation)|go:"GO:0090220"(chromosome localization to nuclear envelope involved in homologous chromosome segregation)|go:"GO:0090619"(meiotic spindle pole)|interpro:IPR011992(EF-Hand type)|interpro:IPR028168|interpro:IPR028170|interpro:IPR039508|mint:Q8N6L0|rcsb pdb:6R2I|rcsb pdb:6WMF|entrezgene/locuslink:147872(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:SvwjVFPBttBj4iLtjQSzRM4+w+E559292	rogid:Wl9L7AcvDHCZuKjYLn8QgGIbZTc9606	intact-crc:9E58DF50D9DDF619|rigid:d3Li+yGLH97Yu1w/g+m3e/WKWPI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96BA8	uniprotkb:P53906	intact:EBI-6942903|ensembl:ENSP00000481956|intact:MINT-268046|intact:MINT-8162577|uniprotkb:Q8N2D5|uniprotkb:Q96CP0	intact:EBI-28943|ensemblfungi:YNL146W|uniprotkb:D6W137	psi-mi:cr3l1_human(display_long)|uniprotkb:CREB3L1(gene name)|psi-mi:CREB3L1(display_short)|uniprotkb:OASIS(gene name synonym)|uniprotkb:PSEC0238(orf name)|uniprotkb:Old astrocyte specifically-induced substance(gene name synonym)	psi-mi:yno6_yeast(display_long)|uniprotkb:N1203(orf name)|uniprotkb:N1785(orf name)|uniprotkb:YNL146W(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11544306|imex:IM-24995-2316	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157613(gene)|ensembl:ENST00000621158(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0070278"(extracellular matrix constituent secretion)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029805|mint:Q96BA8|reactome:R-HSA-8874211|refseq:NP_443086.1|entrezgene/locuslink:90993(identity)	sgd:S000005090|ensemblfungi:YNL146W(gene)|refseq:NP_014253.3|dip:DIP-8009N|ensemblfungi:YNL146W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|sgd:YNL146W(identity)	-	comment:mint|function:"Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE"	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:sMWUFmBeBBCO+T0Y2CuB/un1lBg9606	rogid:SvwjVFPBttBj4iLtjQSzRM4+w+E559292	intact-crc:955519D322E2A29B|rigid:/A0HvqM6hwAcrJl7MjWObv4NNjc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P43365	uniprotkb:P53923	intact:EBI-749530|uniprotkb:Q9NSD3|intact:EBI-10178394|uniprotkb:Q6FHH8|ensembl:ENSP00000350592|ensembl:ENSP00000377447|ensembl:ENSP00000377478	intact:EBI-28871|uniprotkb:B0KZW1|uniprotkb:B0L006|uniprotkb:Q66R25|uniprotkb:B0KZR6|uniprotkb:B0KZS5|uniprotkb:B0KZU3|uniprotkb:D6W163|ensemblfungi:YNL119W	psi-mi:magac_human(display_long)|uniprotkb:MAGE-12 antigen(gene name synonym)|uniprotkb:MAGE12F antigen(gene name synonym)|uniprotkb:Cancer/testis antigen 1.12(gene name synonym)|uniprotkb:MAGEA12(gene name)|psi-mi:MAGEA12(display_short)|uniprotkb:MAGE12(gene name synonym)	psi-mi:ctu2_yeast(display_long)|uniprotkb:TUC2(gene name synonym)|uniprotkb:N1913(orf name)|uniprotkb:YNL119W(locus name)|uniprotkb:NCS2(gene name)|psi-mi:NCS2(display_short)|uniprotkb:Thiolation of uridine in cytoplasmic tRNA protein 2(gene name synonym)|uniprotkb:CTU2(gene name synonym)|uniprotkb:Needs CLA4 to survive protein 2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11544327|imex:IM-24995-2318	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001159858.1|refseq:NP_001159859.1|refseq:NP_005358.2|ensembl:ENSG00000213401(gene)|ensembl:ENST00000357916(transcript)|ensembl:ENST00000393869(transcript)|ensembl:ENST00000393900(transcript)|interpro:IPR002190(MAGE protein)|interpro:IPR021072|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|entrezgene/locuslink:4111(identity)	sgd:S000005063|refseq:NP_014280.3|dip:DIP-6649N|mint:P53923|ensemblfungi:YNL119W(gene)|ensemblfungi:YNL119W_mRNA(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0002143"(tRNA wobble position uridine thiolation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0016783"(sulfurtransferase activity)|go:"GO:0032447"(protein urmylation)|go:"GO:0034227"(tRNA thio-modification)|interpro:IPR019407|sgd:YNL119W(identity)	-	-	crc64:420FE465B982C43E	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:3/Jxz2VsFOb67RWqWj3xbTrw3s49606	rogid:TRbLQjCai4jNx+1IaH76vforp8c559292	intact-crc:E585620DCA8E2F4D|rigid:FIQmuXNX1WIeQSZFeh016yybyrw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q6P1W5	uniprotkb:P53919	intact:EBI-946029|uniprotkb:B3KVT1|uniprotkb:Q96IC8|ensembl:ENSP00000435634|uniprotkb:D3DPR3|uniprotkb:E9PJ76	intact:EBI-28887|uniprotkb:B0KZR2|uniprotkb:B0KZS1|uniprotkb:B0KZT9|uniprotkb:B0KZZ3|uniprotkb:B0L002|uniprotkb:D6W159|ensemblfungi:YNL124W	psi-mi:ca094_human(display_long)|uniprotkb:C1orf94(gene name)|psi-mi:C1orf94(display_short)	psi-mi:naf1_yeast(display_long)|uniprotkb:YNL124W(locus name)|uniprotkb:N1888(orf name)|uniprotkb:NAF1(gene name)|psi-mi:NAF1(display_short)|uniprotkb:Nuclear assembly factor 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11544316|imex:IM-24995-2317	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001128206.1|refseq:NP_116273.2|ensembl:ENSG00000142698(gene)|ensembl:ENST00000488417(transcript)|interpro:IPR031496|entrezgene/locuslink:84970(identity)	sgd:S000005068|refseq:NP_014275.3|dip:DIP-4345N|ensemblfungi:YNL124W(gene)|ensemblfungi:YNL124W_mRNA(transcript)|go:"GO:0000493"(box H/ACA snoRNP assembly)|go:"GO:0001522"(pseudouridine synthesis)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005732"("sno(s)RNA-containing ribonucleoprotein complex")|go:"GO:0006364"(rRNA processing)|go:"GO:0042254"(ribosome biogenesis)|interpro:IPR007504(Gar1 protein RNA-binding region)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR038664|interpro:IPR040309|rcsb pdb:2V3M|sgd:YNL124W(identity)	-	-	crc64:5A496278070F6255	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:y1o4xWvTl2CBA1J7jsP7y8ZjLzM9606	rogid:9ZtegpRDLFL25BUqw4ke9qJ393Q559292	intact-crc:A26E1B4AE30A8A1C|rigid:OrHkMbBJnu8C5r+nNaJaggvPGMs	false	sufficient binding region:191-598	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P53927	uniprotkb:Q9H190	intact:EBI-28853|uniprotkb:D6W171|ensemblfungi:YNL110C	intact:EBI-742426|ensembl:ENSP00000371233|uniprotkb:O95892|uniprotkb:Q5W0X1|uniprotkb:Q9BZ42|uniprotkb:Q9H567|uniprotkb:Q9NRY8|intact:EBI-28983470|ensembl:ENSP00000342935|ensembl:ENSP00000354013	psi-mi:nop15_yeast(display_long)|uniprotkb:YNL110C(locus name)|uniprotkb:N1954(orf name)|uniprotkb:Nucleolar protein 15(gene name synonym)|uniprotkb:NOP15(gene name)|psi-mi:NOP15(display_short)	psi-mi:sdcb2_human(display_long)|uniprotkb:Similar to TACIP18(gene name synonym)|uniprotkb:SDCBP2(gene name)|psi-mi:SDCBP2(display_short)|uniprotkb:SITAC18(gene name synonym)|uniprotkb:Syndecan-binding protein 2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11544336|imex:IM-24995-2319	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014289.1|sgd:S000005054|dip:DIP-4741N|mint:P53927|ensemblfungi:YNL110C(gene)|ensemblfungi:YNL110C_mRNA(transcript)|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0019843"(rRNA binding)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0042273"(ribosomal large subunit biogenesis)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034469|interpro:IPR035979|rcsb pdb:3JCT|rcsb pdb:5T9P|rcsb pdb:5Z3G|rcsb pdb:6C0F|rcsb pdb:6CB1|rcsb pdb:6ELZ|rcsb pdb:6EM1|rcsb pdb:6EM3|rcsb pdb:6EM4|rcsb pdb:6EM5|rcsb pdb:6M62|rcsb pdb:6YLX|rcsb pdb:6YLY|rcsb pdb:7BTB|sgd:YNL110C(identity)	refseq:NP_001186713.1|refseq:NP_056500.2|refseq:NP_536737.3|ensembl:ENSP00000342935|ensembl:ENSP00000354013|ensembl:ENST00000381808|ensembl:ENSP00000371229|ensembl:ENSP00000371233|ensembl:ENSG00000125775(gene)|ensembl:ENST00000360779(transcript)|ensembl:ENST00000381812(transcript)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007399"(nervous system development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016607"(nuclear speck)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046907"(intracellular transport)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036034|interpro:IPR041489|ensembl:ENST00000339987(transcript)|entrezgene/locuslink:27111(identity)	-	crc64:EC86E3C77C863292	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:WHuY5zx7DUsm1G+00Bc6wM8JAJc559292	rogid:vlEtVZkwLTte5PJ4i8ce+SwE/4Y9606	intact-crc:88EAFA0B5C93189D|rigid:/s3CJWR5qBcco0QZMZrfaau1PRs	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P53933	uniprotkb:Q08379	intact:EBI-28798|uniprotkb:D6W186|ensemblfungi:YNL094W	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	psi-mi:app1_yeast(display_long)|uniprotkb:APP1(gene name)|psi-mi:APP1(display_short)|uniprotkb:Actin patch protein 1(gene name synonym)|uniprotkb:N2219(orf name)|uniprotkb:YNL094W(locus name)	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11544364|imex:IM-24995-2322	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014305.1|sgd:S000005038|dip:DIP-2006N|mint:P53933|ensemblfungi:YNL094W(gene)|ensemblfungi:YNL094W_mRNA(transcript)|go:"GO:0008195"(phosphatidate phosphatase activity)|go:"GO:0030479"(actin cortical patch)|go:"GO:0044255"(cellular lipid metabolic process)|interpro:IPR017210(Uncharacterised conserved protein UCP037464, actin patch protein 1)|interpro:IPR019236|sgd:YNL094W(identity)	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N|entrezgene/locuslink:2801(identity)	-	crc64:B85C525548BA34BC	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2017/05/26	rogid:4ORrWVN2DOL+59LI2qWcKYYVfcE559292	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	intact-crc:D0EF36DDD43BDCC8|rigid:aZJHRGm/s29HLT82oyU7qLPpuxw	false	-	sufficient binding region:383-1002	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P53930	uniprotkb:Q13155	intact:EBI-28841|uniprotkb:Q6B1N1|uniprotkb:D6W173|ensemblfungi:YNL107W	intact:EBI-745226|uniprotkb:Q75MR1|uniprotkb:Q96CZ5|uniprotkb:Q9P1L2|ensembl:ENSP00000223029|uniprotkb:F8W950	psi-mi:af9_yeast(display_long)|uniprotkb:N1966(orf name)|uniprotkb:YNL107W(locus name)|uniprotkb:YAF9(gene name)|psi-mi:YAF9(display_short)	psi-mi:aimp2_human(display_long)|uniprotkb:Protein JTV-1(gene name synonym)|uniprotkb:AIMP2(gene name)|psi-mi:AIMP2(display_short)|uniprotkb:PRO0992(orf name)|uniprotkb:JTV1(gene name synonym)|uniprotkb:Multisynthase complex auxiliary component p38(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11544345|imex:IM-24995-2320	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005051|refseq:NP_014292.3|dip:DIP-4347N|mint:P53930|ensemblfungi:YNL107W(gene)|ensemblfungi:YNL107W_mRNA(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000812"(Swr1 complex)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006348"|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0043486"(histone exchange)|interpro:IPR005033(YEATS)|interpro:IPR037989|interpro:IPR038704|rcsb pdb:3FK3|rcsb pdb:3RLS|rcsb pdb:6AXJ|reactome:R-SCE-674695|reactome:R-SCE-75955|sgd:YNL107W(identity)	refseq:NP_006294.2|ensembl:ENSG00000106305(gene)|ensembl:ENST00000223029(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0006915"(apoptotic process)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0017101"(aminoacyl-tRNA synthetase multienzyme complex)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060510"(type II pneumocyte differentiation)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1903632"(positive regulation of aminoacyl-tRNA ligase activity)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR031889|interpro:IPR036282|interpro:IPR041503|interpro:IPR042360|mint:Q13155|rcsb pdb:4DPG|rcsb pdb:4YCU|rcsb pdb:4YCW|rcsb pdb:5A1N|rcsb pdb:5A34|rcsb pdb:5A5H|rcsb pdb:5Y6L|rcsb pdb:6ILD|rcsb pdb:6IY6|rcsb pdb:6JPV|rcsb pdb:6K39|reactome:R-HSA-2408522|reactome:R-HSA-379716|dip:DIP-34421N|refseq:NP_001313536.1|entrezgene/locuslink:7965(identity)	-	crc64:1FE08F72942061D1	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:oIwHCTPMu/kBEXUm82Yw5C0YYXw559292	rogid:VEBmJjo6t3dBY6mKpmUyVLamJFQ9606	intact-crc:2524F196F60E9B7D|rigid:WBnb8LWe6+acKCVJpW2TGVkKTlg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P53930	uniprotkb:Q53HC0	intact:EBI-28841|uniprotkb:Q6B1N1|uniprotkb:D6W173|ensemblfungi:YNL107W	intact:EBI-719994|uniprotkb:Q9H697|uniprotkb:B3KNQ0|ensembl:ENSP00000238156|ensembl:ENSP00000488830	psi-mi:af9_yeast(display_long)|uniprotkb:N1966(orf name)|uniprotkb:YNL107W(locus name)|uniprotkb:YAF9(gene name)|psi-mi:YAF9(display_short)	psi-mi:ccd92_human(display_long)|uniprotkb:Limkain beta-2(gene name synonym)|uniprotkb:CCDC92(gene name)|psi-mi:CCDC92(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11544355|imex:IM-24995-2321	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005051|refseq:NP_014292.3|dip:DIP-4347N|mint:P53930|ensemblfungi:YNL107W(gene)|ensemblfungi:YNL107W_mRNA(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000812"(Swr1 complex)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006348"|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0043486"(histone exchange)|interpro:IPR005033(YEATS)|interpro:IPR037989|interpro:IPR038704|rcsb pdb:3FK3|rcsb pdb:3RLS|rcsb pdb:6AXJ|reactome:R-SCE-674695|reactome:R-SCE-75955|sgd:YNL107W(identity)	refseq:NP_079416.1|ensembl:ENSG00000119242(gene)|ensembl:ENSG00000275035(gene)|ensembl:ENST00000238156(transcript)|ensembl:ENST00000632401(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR033224|interpro:IPR039496|interpro:IPR040370|mint:Q53HC0|refseq:NP_001291886.1|refseq:NP_001291887.1|refseq:NP_001291888.1|refseq:NP_001291889.1|refseq:NP_001291890.1|refseq:XP_005253681.1|refseq:XP_016875473.1|entrezgene/locuslink:80212(identity)	-	crc64:1FE08F72942061D1	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:oIwHCTPMu/kBEXUm82Yw5C0YYXw559292	rogid:Iu/FzTqEpzn8N5WUTt1OwoKWxyc9606	intact-crc:9B85217C321C1790|rigid:So1yakNwnIwuhyz0Ca1SI8vUTvg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P14373	uniprotkb:P53933	intact:EBI-719493|uniprotkb:A2BE15|uniprotkb:Q5RJA8|uniprotkb:Q5ST26|uniprotkb:Q6LA73|uniprotkb:Q6NXR9|uniprotkb:Q9BZY6|uniprotkb:Q9UJL3|ensembl:ENSP00000383555|ensembl:ENSP00000392787|ensembl:ENSP00000405229|ensembl:ENSP00000414793|ensembl:ENSP00000366404	intact:EBI-28798|uniprotkb:D6W186|ensemblfungi:YNL094W	psi-mi:tri27_human(display_long)|uniprotkb:TRIM27(gene name)|psi-mi:TRIM27(display_short)|uniprotkb:RNF76(gene name synonym)|uniprotkb:RFP(gene name synonym)|uniprotkb:Ret finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 27(gene name synonym)|uniprotkb:RING finger protein 76(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM27(gene name synonym)	psi-mi:app1_yeast(display_long)|uniprotkb:APP1(gene name)|psi-mi:APP1(display_short)|uniprotkb:Actin patch protein 1(gene name synonym)|uniprotkb:N2219(orf name)|uniprotkb:YNL094W(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11544384|imex:IM-24995-2324	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006501.1|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0090281"(negative regulation of calcium ion import)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR020457|interpro:IPR035791|interpro:IPR043136|mint:P14373|reactome:R-HSA-3232142|reactome:R-HSA-9635465|reactome:R-HSA-8948751|ensembl:ENSG00000204713(gene)|ensembl:ENSG00000215641(gene)|ensembl:ENSG00000229006(gene)|ensembl:ENSG00000234495(gene)|ensembl:ENSG00000237071(gene)|ensembl:ENST00000377199(transcript)|ensembl:ENST00000400720(transcript)|ensembl:ENST00000431123(transcript)|ensembl:ENST00000435528(transcript)|ensembl:ENST00000437160(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001650"(fibrillar center)|go:"GO:0002820"(negative regulation of adaptive immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|entrezgene/locuslink:5987(identity)	refseq:NP_014305.1|sgd:S000005038|dip:DIP-2006N|mint:P53933|ensemblfungi:YNL094W(gene)|ensemblfungi:YNL094W_mRNA(transcript)|go:"GO:0008195"(phosphatidate phosphatase activity)|go:"GO:0030479"(actin cortical patch)|go:"GO:0044255"(cellular lipid metabolic process)|interpro:IPR017210(Uncharacterised conserved protein UCP037464, actin patch protein 1)|interpro:IPR019236|sgd:YNL094W(identity)	-	-	crc64:B85C525548BA34BC	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:dsfH5OUghD8KSaTz1SFw9OYVTK49606	rogid:4ORrWVN2DOL+59LI2qWcKYYVfcE559292	intact-crc:3A2E07FB16641B87|rigid:p9Jc60yOsm+pNpOb2wwtG/yIjMQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P53933	uniprotkb:O95273	intact:EBI-28798|uniprotkb:D6W186|ensemblfungi:YNL094W	intact:EBI-748961|uniprotkb:A8K3Q0|uniprotkb:A8K3U2|uniprotkb:Q6ZQN9|uniprotkb:Q7Z519|uniprotkb:Q8NBS7|uniprotkb:Q8NBY2|uniprotkb:Q9NS19|uniprotkb:Q9NYH3|uniprotkb:Q9UHX9|ensembl:ENSP00000300213	psi-mi:app1_yeast(display_long)|uniprotkb:APP1(gene name)|psi-mi:APP1(display_short)|uniprotkb:Actin patch protein 1(gene name synonym)|uniprotkb:N2219(orf name)|uniprotkb:YNL094W(locus name)	psi-mi:ccdb1_human(display_long)|uniprotkb:Grap2 and cyclin-D-interacting protein(gene name synonym)|uniprotkb:Human homolog of Maid(gene name synonym)|uniprotkb:CCNDBP1(gene name)|psi-mi:CCNDBP1(display_short)|uniprotkb:DIP1(gene name synonym)|uniprotkb:GCIP(gene name synonym)|uniprotkb:HHM(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11544375|imex:IM-24995-2323	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014305.1|sgd:S000005038|dip:DIP-2006N|mint:P53933|ensemblfungi:YNL094W(gene)|ensemblfungi:YNL094W_mRNA(transcript)|go:"GO:0008195"(phosphatidate phosphatase activity)|go:"GO:0030479"(actin cortical patch)|go:"GO:0044255"(cellular lipid metabolic process)|interpro:IPR017210(Uncharacterised conserved protein UCP037464, actin patch protein 1)|interpro:IPR019236|sgd:YNL094W(identity)	refseq:NP_036274.3|ensembl:ENSG00000166946(gene)|ensembl:ENST00000300213(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0016604"(nuclear body)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR026907|mint:O95273|rcsb pdb:3AY5|entrezgene/locuslink:23582(identity)	-	crc64:B85C525548BA34BC	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:4ORrWVN2DOL+59LI2qWcKYYVfcE559292	rogid:Vi9aoFc+Mov6P3X6KGmsTxXqxvM9606	intact-crc:AA129F4A586D22AA|rigid:iivbEsNNyXz10fs2+QP+UQnmd68	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P53933	uniprotkb:Q9Y5X1	intact:EBI-28798|uniprotkb:D6W186|ensemblfungi:YNL094W	intact:EBI-77848|ensembl:ENSP00000376024|ensembl:ENSP00000506326|uniprotkb:Q9BSI7|uniprotkb:Q9BVM1|uniprotkb:Q9UJH6|uniprotkb:Q9UP20	psi-mi:app1_yeast(display_long)|uniprotkb:APP1(gene name)|psi-mi:APP1(display_short)|uniprotkb:Actin patch protein 1(gene name synonym)|uniprotkb:N2219(orf name)|uniprotkb:YNL094W(locus name)	psi-mi:snx9_human(display_long)|uniprotkb:SNX9(gene name)|psi-mi:SNX9(display_short)|uniprotkb:SH3PX1(gene name synonym)|uniprotkb:SH3PXD3A(gene name synonym)|uniprotkb:SH3 and PX domain-containing protein 1(gene name synonym)|uniprotkb:SH3 and PX domain-containing protein 3A(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11544411|imex:IM-24995-2327	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014305.1|sgd:S000005038|dip:DIP-2006N|mint:P53933|ensemblfungi:YNL094W(gene)|ensemblfungi:YNL094W_mRNA(transcript)|go:"GO:0008195"(phosphatidate phosphatase activity)|go:"GO:0030479"(actin cortical patch)|go:"GO:0044255"(cellular lipid metabolic process)|interpro:IPR017210(Uncharacterised conserved protein UCP037464, actin patch protein 1)|interpro:IPR019236|sgd:YNL094W(identity)	ensembl:ENSG00000130340(gene)|ensembl:ENST00000392185(transcript)|ensembl:ENST00000679814(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0001726"(ruffle)|go:"GO:0005545"(1-phosphatidylinositol binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006897"(endocytosis)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0016197"(endosomal transport)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032437"(cuticular plate)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0036089"(cleavage furrow formation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0051044"(positive regulation of membrane protein ectodomain proteolysis)|go:"GO:0060988"(lipid tube assembly)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071933"(Arp2/3 complex binding)|go:"GO:0097320"(plasma membrane tubulation)|interpro:IPR001452(Src homology-3)|interpro:IPR001683(Phox-like)|interpro:IPR014536(Sorting nexin, Snx9 type)|interpro:IPR019497|interpro:IPR027267|interpro:IPR028644|interpro:IPR035558|interpro:IPR036028|interpro:IPR036871|interpro:IPR037425|interpro:IPR037426|mint:Q9Y5X1|rcsb pdb:2RAI|rcsb pdb:2RAJ|rcsb pdb:2RAK|rcsb pdb:3DYT|rcsb pdb:3DYU|rcsb pdb:3LGE|reactome:R-HSA-432722|reactome:R-HSA-8856828|refseq:NP_057308.1|dip:DIP-30997N|entrezgene/locuslink:51429(identity)	-	crc64:B85C525548BA34BC	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:4ORrWVN2DOL+59LI2qWcKYYVfcE559292	rogid:qtqmMew2psrK6OJPAOWQGTVmNJA9606	intact-crc:5F42796F4C4E22EF|rigid:heE4QMrICB90mjOoLbcWatLpn+8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P53933	uniprotkb:Q9Y6D9	intact:EBI-28798|uniprotkb:D6W186|ensemblfungi:YNL094W	intact:EBI-742610|uniprotkb:B3KR41|uniprotkb:Q9UNH0|uniprotkb:Q13312|uniprotkb:Q75MI0|uniprotkb:Q86UM4|ensembl:ENSP00000265854|ensembl:ENSP00000382562|ensembl:ENSP00000385334	psi-mi:app1_yeast(display_long)|uniprotkb:APP1(gene name)|psi-mi:APP1(display_short)|uniprotkb:Actin patch protein 1(gene name synonym)|uniprotkb:N2219(orf name)|uniprotkb:YNL094W(locus name)	psi-mi:md1l1_human(display_long)|uniprotkb:Mitotic arrest deficient 1-like protein 1(gene name synonym)|uniprotkb:Mitotic checkpoint MAD1 protein homolog(gene name synonym)|uniprotkb:Tax-binding protein 181(gene name synonym)|uniprotkb:MAD1L1(gene name)|psi-mi:MAD1L1(display_short)|uniprotkb:MAD1(gene name synonym)|uniprotkb:TXBP181(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11544420|imex:IM-24995-2328	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014305.1|sgd:S000005038|dip:DIP-2006N|mint:P53933|ensemblfungi:YNL094W(gene)|ensemblfungi:YNL094W_mRNA(transcript)|go:"GO:0008195"(phosphatidate phosphatase activity)|go:"GO:0030479"(actin cortical patch)|go:"GO:0044255"(cellular lipid metabolic process)|interpro:IPR017210(Uncharacterised conserved protein UCP037464, actin patch protein 1)|interpro:IPR019236|sgd:YNL094W(identity)	refseq:NP_001013858.1|refseq:NP_001013859.1|refseq:NP_003541.2|refseq:NP_001291452.1|refseq:NP_001291453.1|ensembl:ENSG00000002822(gene)|ensembl:ENST00000265854(transcript)|go:"GO:0090235"(regulation of metaphase plate congression)|go:"GO:1902426"(deactivation of mitotic spindle assembly checkpoint)|interpro:IPR008672(Mitotic checkpoint)|mint:Q9Y6D9|rcsb pdb:1GO4|rcsb pdb:4DZO|rcsb pdb:7B1F|rcsb pdb:7B1H|rcsb pdb:7B1J|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|ensembl:ENST00000399654(transcript)|ensembl:ENST00000406869(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043515"(kinetochore binding)|go:"GO:0044615"(nuclear pore nuclear basket)|go:"GO:0048538"(thymus development)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0072686"(mitotic spindle)|refseq:XP_005249934.1|dip:DIP-29654N|entrezgene/locuslink:8379(identity)	-	crc64:B85C525548BA34BC	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:4ORrWVN2DOL+59LI2qWcKYYVfcE559292	rogid:9CcqpZlN0IgqC939rIo7vNgOvLQ9606	intact-crc:A55B725077B9111F|rigid:DNKK0rxktXI+kd4CBEvrsnfZ2CA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UNF0	uniprotkb:P53933	intact:EBI-742503|uniprotkb:O95921|uniprotkb:Q96HV9|uniprotkb:Q9H0D3|uniprotkb:Q9NPN1|uniprotkb:Q9Y4V2|ensembl:ENSP00000385040|ensembl:ENSP00000385372|ensembl:ENSP00000263246	intact:EBI-28798|uniprotkb:D6W186|ensemblfungi:YNL094W	psi-mi:pacn2_human(display_long)|uniprotkb:PACSIN2(gene name)|psi-mi:PACSIN2(display_short)|uniprotkb:Syndapin-II(gene name synonym)|uniprotkb:Syndapin-2(gene name synonym)	psi-mi:app1_yeast(display_long)|uniprotkb:APP1(gene name)|psi-mi:APP1(display_short)|uniprotkb:Actin patch protein 1(gene name synonym)|uniprotkb:N2219(orf name)|uniprotkb:YNL094W(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11544402|imex:IM-24995-2326	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001171899.1|refseq:NP_001171900.1|refseq:NP_009160.2|refseq:XP_005261376.1|refseq:XP_016884053.1|ensembl:ENST00000263246(transcript)|ensembl:ENST00000402229(transcript)|ensembl:ENST00000403744(transcript)|go:"GO:0005215"(transporter activity)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|ensembl:ENSG00000100266(gene)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0032587"(ruffle membrane)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045296"(cadherin binding)|go:"GO:0045806"(negative regulation of endocytosis)|go:"GO:0048858"(cell projection morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070300"(phosphatidic acid binding)|go:"GO:0070836"(caveola assembly)|go:"GO:0072584"(caveolin-mediated endocytosis)|go:"GO:0097320"(plasma membrane tubulation)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR027267|interpro:IPR028521|interpro:IPR031160|interpro:IPR035743|interpro:IPR036028|interpro:IPR037453|mint:Q9UNF0|rcsb pdb:3ABH|rcsb pdb:3ACO|rcsb pdb:3HAJ|rcsb pdb:3Q0K|reactome:R-HSA-8856828|entrezgene/locuslink:11252(identity)	refseq:NP_014305.1|sgd:S000005038|dip:DIP-2006N|mint:P53933|ensemblfungi:YNL094W(gene)|ensemblfungi:YNL094W_mRNA(transcript)|go:"GO:0008195"(phosphatidate phosphatase activity)|go:"GO:0030479"(actin cortical patch)|go:"GO:0044255"(cellular lipid metabolic process)|interpro:IPR017210(Uncharacterised conserved protein UCP037464, actin patch protein 1)|interpro:IPR019236|sgd:YNL094W(identity)	-	-	crc64:B85C525548BA34BC	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:oEGsyQlsPg61RRGLjBdPGKDmkXc9606	rogid:4ORrWVN2DOL+59LI2qWcKYYVfcE559292	intact-crc:444C3501643861B6|rigid:NP6BsaMOKux/N0SroiC1XlUAyrw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q15642-2	uniprotkb:P53933	intact:EBI-6550597|ensembl:ENSP00000320493	intact:EBI-28798|uniprotkb:D6W186|ensemblfungi:YNL094W	psi-mi:q15642-2(display_long)|uniprotkb:A(isoform synonym)|uniprotkb:W(isoform synonym)|uniprotkb:TRIP10(gene name)|psi-mi:TRIP10(display_short)|uniprotkb:CIP4(gene name synonym)|uniprotkb:STOT(gene name synonym)|uniprotkb:STP(gene name synonym)|uniprotkb:Protein Felic(gene name synonym)|uniprotkb:Salt tolerant protein(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 10(gene name synonym)	psi-mi:app1_yeast(display_long)|uniprotkb:APP1(gene name)|psi-mi:APP1(display_short)|uniprotkb:Actin patch protein 1(gene name synonym)|uniprotkb:N2219(orf name)|uniprotkb:YNL094W(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11544393|imex:IM-24995-2325	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:Q15642-2(isoform-parent)|ensembl:ENSG00000125733(gene)|ensembl:ENST00000313285(transcript)|intact:EBI-739936(isoform-parent)|entrezgene/locuslink:9322(identity)	refseq:NP_014305.1|sgd:S000005038|dip:DIP-2006N|mint:P53933|ensemblfungi:YNL094W(gene)|ensemblfungi:YNL094W_mRNA(transcript)|go:"GO:0008195"(phosphatidate phosphatase activity)|go:"GO:0030479"(actin cortical patch)|go:"GO:0044255"(cellular lipid metabolic process)|interpro:IPR017210(Uncharacterised conserved protein UCP037464, actin patch protein 1)|interpro:IPR019236|sgd:YNL094W(identity)	-	-	crc64:B85C525548BA34BC	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:FppLeIANQu5tcNbD11u+F0kSOBQ9606	rogid:4ORrWVN2DOL+59LI2qWcKYYVfcE559292	intact-crc:902ECCFA47F9DEBC|rigid:eMVEToYrW+Tmvt0fj+E8dB1WpiE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q969F0	uniprotkb:P54074	intact:EBI-743099|ensembl:ENSP00000359375	intact:EBI-27241|uniprotkb:D6VZU2|ensemblfungi:YMR119W	psi-mi:fate1_human(display_long)|uniprotkb:Tumor antigen BJ-HCC-2(gene name synonym)|uniprotkb:Cancer/testis antigen 43(gene name synonym)|uniprotkb:FATE1(gene name)|psi-mi:FATE1(display_short)|uniprotkb:FATE(gene name synonym)	psi-mi:asi1_yeast(display_long)|uniprotkb:YMR119W(locus name)|uniprotkb:YM9718.18(orf name)|uniprotkb:YM8564.01(orf name)|uniprotkb:Amino acid sensor-independent protein 1(gene name synonym)|uniprotkb:ASI1(gene name)|psi-mi:ASI1(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11544447|imex:IM-24995-2331	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_149076.1|ensembl:ENSG00000147378(gene)|ensembl:ENST00000370350(transcript)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|go:"GO:0051562"(negative regulation of mitochondrial calcium ion concentration)|interpro:IPR039153|interpro:IPR039433|mint:Q969F0|entrezgene/locuslink:89885(identity)	refseq:NP_013837.1|sgd:S000004725|dip:DIP-7733N|ensemblfungi:YMR119W(gene)|ensemblfungi:YMR119W_mRNA(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034399"(nuclear periphery)|go:"GO:0036369"(transcription factor catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0097658"(Asi complex)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|sgd:YMR119W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Nm1N6lO92MHr5rIKC007oouF5RE9606	rogid:CvH0AkCWby1t6LwuYC0K/dI2jgo559292	intact-crc:6312BC08BF82CED0|rigid:9yTvzpIj8pynG9tcp0PMLW1HC3U	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q53G59	uniprotkb:P53953	intact:EBI-740929|ensembl:ENSP00000356230|uniprotkb:A6NEN8|uniprotkb:B7Z7B8|uniprotkb:Q9HBX5	intact:EBI-17006|uniprotkb:D6W1D0|ensemblfungi:YNL049C	psi-mi:klh12_human(display_long)|uniprotkb:CUL3-interacting protein 1(gene name synonym)|uniprotkb:KLHL12(gene name)|psi-mi:KLHL12(display_short)|uniprotkb:C3IP1(gene name synonym)|uniprotkb:DKIR homolog(gene name synonym)	psi-mi:sfb2_yeast(display_long)|uniprotkb:SFB2(gene name)|psi-mi:SFB2(display_short)|uniprotkb:ISS1(gene name synonym)|uniprotkb:YNL049C(locus name)|uniprotkb:N2505(orf name)|uniprotkb:YNL2505C(orf name)|uniprotkb:SEC24-related protein 2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11544438|imex:IM-24995-2330	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048208"(COPII vesicle coating)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR017096(Kelch-like protein, gigaxonin)|mint:Q53G59|rcsb pdb:2VPJ|rcsb pdb:6TTK|rcsb pdb:6V7O|reactome:R-HSA-4641258|refseq:NP_067646.1|ensembl:ENSG00000117153(gene)|ensembl:ENST00000367261(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0014029"(neural crest formation)|go:"GO:0014032"(neural crest cell development)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0034451"(centriolar satellite)|refseq:NP_001289980.1|refseq:NP_001290038.1|entrezgene/locuslink:59349(identity)	ensemblfungi:YNL049C(gene)|ensemblfungi:YNL049C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0005048"(signal sequence binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:0090110"(COPII-coated vesicle cargo loading)|interpro:IPR006896(Sec23/Sec24 trunk region)|interpro:IPR006900(Sec23/Sec24 helical region)|interpro:IPR007123(Gelsolin region)|interpro:IPR012990(Sec23/Sec24 beta-sandwich)|interpro:IPR029006|interpro:IPR036174|interpro:IPR036175|interpro:IPR036180|interpro:IPR036465|interpro:IPR041742|reactome:R-SCE-204005|reactome:R-SCE-5694530|reactome:R-SCE-983170|interpro:IPR006895(Zinc finger, Sec23/Sec24-type)|refseq:NP_014349.1|sgd:S000004994|dip:DIP-4370N|mint:P53953|sgd:YNL049C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:C4I/Ys9vqNqfG61HsXRZhywP4vE9606	rogid:rG9Y9x8CduERmQuwFxUU/Z/wD1A559292	intact-crc:9ED8EB12720C0617|rigid:f+ZAsu7g439pPlhuwB+oe75JgIs	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P53949	uniprotkb:Q96CN4	intact:EBI-28725|uniprotkb:Q6B2U7|uniprotkb:D6W1C2|ensemblfungi:YNL056W	intact:EBI-749523|uniprotkb:B9A6I9|ensembl:ENSP00000270530	psi-mi:oca2_yeast(display_long)|uniprotkb:YNL056W(locus name)|uniprotkb:N2439(orf name)|uniprotkb:YNL2439W(orf name)|uniprotkb:Oxidant-induced cell-cycle arrest protein 2(gene name synonym)|uniprotkb:OCA2(gene name)|psi-mi:OCA2(display_short)	psi-mi:evi5l_human(display_long)|uniprotkb:Ecotropic viral integration site 5-like protein(gene name synonym)|uniprotkb:EVI5L(gene name)|psi-mi:EVI5L(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11544429|imex:IM-24995-2329	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005001|refseq:NP_014342.3|dip:DIP-1989N|mint:P53949|ensemblfungi:YNL056W(gene)|ensemblfungi:YNL056W_mRNA(transcript)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005737"(cytoplasm)|interpro:IPR004861(Protein-tyrosine phosphatase, SIW14-like)|interpro:IPR020422|interpro:IPR029021|sgd:YNL056W(identity)	refseq:NP_001153416.1|refseq:NP_660288.1|refseq:XP_005272515.1|refseq:XP_016881728.1|ensembl:ENSG00000142459(gene)|ensembl:ENST00000270530(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0031267"(small GTPase binding)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:1902018"(negative regulation of cilium assembly)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR031214|interpro:IPR035969|entrezgene/locuslink:115704(identity)	-	crc64:B5CF05FAABD9C236	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Ydjdu1aqlhPFCckVB/BjaRa1ITI559292	rogid:OKfnOqdRupGBmq6gqoeApO0cgG09606	intact-crc:FCCD4B51051DF800|rigid:FiiWoxOKb2DhlfBnfPd0ypQsGbc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P54860	uniprotkb:Q9UMX0	intact:EBI-20003|uniprotkb:D6VRG3|ensemblfungi:YDL190C	intact:EBI-741480|uniprotkb:Q8IXS9|uniprotkb:Q8N2Q3|uniprotkb:Q9H0T8|uniprotkb:Q9H3R4|uniprotkb:Q9HAZ5|intact:EBI-28967608|ensembl:ENSP00000365576|uniprotkb:Q5T6J5|uniprotkb:Q5T6J9|uniprotkb:A0A024R284	psi-mi:ufd2_yeast(display_long)|uniprotkb:UFD2(gene name)|psi-mi:UFD2(display_short)|uniprotkb:YDL190C(locus name)|uniprotkb:D1255(orf name)|uniprotkb:Ubiquitin fusion degradation protein 2(gene name synonym)|uniprotkb:Ubiquitin conjugation factor E4(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase UFD2(gene name synonym)	psi-mi:ubql1_human(display_long)|uniprotkb:Protein linking IAP with cytoskeleton 1(gene name synonym)|uniprotkb:UBQLN1(gene name)|psi-mi:UBQLN1(display_short)|uniprotkb:DA41(gene name synonym)|uniprotkb:PLIC1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11544496|imex:IM-24995-2336	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010091.2|sgd:S000002349|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR003613(U box)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|go:"GO:0016567"(protein ubiquitination)|interpro:IPR019474|rcsb pdb:2QIZ|rcsb pdb:2QJ0|rcsb pdb:3M62|rcsb pdb:3M63|reactome:R-SCE-983168|ensemblfungi:YDL190C(gene)|ensemblfungi:YDL190C_mRNA(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|dip:DIP-5925N|mint:P54860|sgd:YDL190C(identity)	ensembl:ENST00000257468|ensembl:ENSP00000257468|ensembl:ENSP00000365576|ensembl:ENSG00000135018(gene)|ensembl:ENST00000376395(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000502"(proteasome complex)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016235"(aggresome)|go:"GO:0016236"(macroautophagy)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0019900"(kinase binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035973"(aggrephagy)|go:"GO:0042802"(identical protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0097352"(autophagosome maturation)|go:"GO:1901340"(negative regulation of store-operated calcium channel activity)|go:"GO:1902175"(regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)|interpro:IPR000626(Ubiquitin)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR028430|interpro:IPR029071|mint:Q9UMX0|rcsb pdb:2JY5|rcsb pdb:2JY6|rcsb pdb:2KLC|reactome:R-HSA-8856825|refseq:NP_038466.2|refseq:NP_444295.1|dip:DIP-41629N|entrezgene/locuslink:29979(identity)	-	crc64:877ACB59AC29634A	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:E8YkPPAM7RTsLwjUHSHNCjQWq9M559292	rogid:nCFfZbGCTvRYaXhQ4R99XblslvM9606	intact-crc:BCA92E9DCD5134D5|rigid:4IfUBzrlDlTBoaaa1l8LS7SojVE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P54791	uniprotkb:Q08379	intact:EBI-12580|uniprotkb:D6W4G3|ensemblfungi:YPR162C	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	psi-mi:orc4_yeast(display_long)|uniprotkb:ORC4(gene name)|psi-mi:ORC4(display_short)|uniprotkb:YPR162C(locus name)|uniprotkb:P9325.5(orf name)|uniprotkb:Origin recognition complex 56 kDa subunit(gene name synonym)	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11544485|imex:IM-24995-2335	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YPR162C(gene)|ensemblfungi:YPR162C_mRNA(transcript)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031261"(DNA replication preinitiation complex)|interpro:IPR016527(Origin recognition complex, subunit 4)|interpro:IPR027417|interpro:IPR032705|rcsb pdb:5V8F|rcsb pdb:5ZR1|rcsb pdb:6RQC|rcsb pdb:6WGC|rcsb pdb:6WGG|rcsb pdb:6WGI|rcsb pdb:7MCA|reactome:R-SCE-68616|reactome:R-SCE-68962|reactome:R-SCE-68949|refseq:NP_015488.1|sgd:S000006366|dip:DIP-2287N|mint:P54791|sgd:YPR162C(identity)	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N|entrezgene/locuslink:2801(identity)	-	crc64:ACF064F2C633F13F	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2017/05/26	rogid:kJZ5UJVsvZNFQEkBR9tmPOJ+Iv8559292	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	intact-crc:F23E3C313C509C93|rigid:DSx17Ve2DO16uWh9vlHWt53cQjM	false	-	sufficient binding region:383-1002	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q15038	uniprotkb:P54787	intact:EBI-724310|ensembl:ENSP00000394699|uniprotkb:E9PB45|uniprotkb:A8K254|uniprotkb:B4DDT5|uniprotkb:C9JA96|uniprotkb:C9JP84|uniprotkb:B4E1G3|uniprotkb:F8VU62	intact:EBI-20495|uniprotkb:D6W0I8|ensemblfungi:YML097C	psi-mi:dazp2_human(display_long)|uniprotkb:Deleted in azoospermia-associated protein 2(gene name synonym)|uniprotkb:DAZAP2(gene name)|psi-mi:DAZAP2(display_short)|uniprotkb:KIAA0058(gene name synonym)	psi-mi:vps9_yeast(display_long)|uniprotkb:VPS9(gene name)|psi-mi:VPS9(display_short)|uniprotkb:Vacuolar protein-targeting protein 9(gene name synonym)|uniprotkb:VPT9(gene name synonym)|uniprotkb:YML097C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11544476|imex:IM-24995-2334	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000183283(gene)|ensembl:ENST00000412716(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0016607"(nuclear speck)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0050699"(WW domain binding)|interpro:IPR022730|mint:Q15038|refseq:NP_001129736.1|refseq:NP_055579.1|ensembl:ENSP00000394699|ensembl:ENST00000425012|ensembl:ENSP00000408251|ensembl:ENST00000439799|ensembl:ENSP00000398804|ensembl:ENST00000449723|ensembl:ENSP00000412812|ensembl:ENST00000549555|ensembl:ENSP00000448051|ensembl:ENST00000549732|ensembl:ENSP00000446554|refseq:NP_001129741.1|refseq:NP_001129739.1|refseq:NP_001129740.1|refseq:NP_001129738.1|entrezgene/locuslink:9802(identity)	refseq:NP_013612.1|sgd:S000004563|ensemblfungi:YML097C(gene)|ensemblfungi:YML097C_mRNA(transcript)|go:"GO:0000011"(vacuole inheritance)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR009060(UBA-like)|interpro:IPR037191|interpro:IPR041545|interpro:IPR041804|rcsb pdb:1MN3|rcsb pdb:1P3Q|reactome:R-SCE-8876198|reactome:R-SCE-8856828|dip:DIP-4526N|mint:P54787|sgd:YML097C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:ASRqCZBG4q1U/y95PUSMKsgfm/g9606	rogid:ogXRiOOp698mlPdAiFidYakMtI4559292	intact-crc:FD053D5A0221D22D|rigid:DwpVDWgt7l//tipQ+xSc9Jye/M8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P54787	uniprotkb:O14641	intact:EBI-20495|uniprotkb:D6W0I8|ensemblfungi:YML097C	intact:EBI-740850|ensembl:ENSP00000005340|uniprotkb:Q53XM0|uniprotkb:D3DTN3	psi-mi:vps9_yeast(display_long)|uniprotkb:VPS9(gene name)|psi-mi:VPS9(display_short)|uniprotkb:Vacuolar protein-targeting protein 9(gene name synonym)|uniprotkb:VPT9(gene name synonym)|uniprotkb:YML097C(locus name)	psi-mi:dvl2_human(display_long)|uniprotkb:DSH homolog 2(gene name synonym)|uniprotkb:DVL2(gene name)|psi-mi:DVL2(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11544467|imex:IM-24995-2333	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013612.1|sgd:S000004563|ensemblfungi:YML097C(gene)|ensemblfungi:YML097C_mRNA(transcript)|go:"GO:0000011"(vacuole inheritance)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR009060(UBA-like)|interpro:IPR037191|interpro:IPR041545|interpro:IPR041804|rcsb pdb:1MN3|rcsb pdb:1P3Q|reactome:R-SCE-8876198|reactome:R-SCE-8856828|dip:DIP-4526N|mint:P54787|sgd:YML097C(identity)	refseq:NP_004413.1|ensembl:ENSG00000004975(gene)|ensembl:ENST00000005340(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005109"(frizzled binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0007507"(heart development)|go:"GO:0016235"(aggresome)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044340"(canonical Wnt signaling pathway involved in regulation of cell proliferation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0150012"(positive regulation of neuron projection arborization)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008341(Dishevelled-2 region)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:O14641|rcsb pdb:2REY|rcsb pdb:3CBX|rcsb pdb:3CBY|rcsb pdb:3CBZ|rcsb pdb:3CC0|rcsb pdb:4WIP|rcsb pdb:5LNP|rcsb pdb:5SUY|rcsb pdb:5SUZ|rcsb pdb:6IW3|rcsb pdb:6JCK|reactome:R-HSA-201681|reactome:R-HSA-201688|reactome:R-HSA-2028269|reactome:R-HSA-4086400|reactome:R-HSA-4608870|reactome:R-HSA-4641258|reactome:R-HSA-4641262|reactome:R-HSA-5099900|reactome:R-HSA-5368598|reactome:R-HSA-5663220|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9673324|ensembl:ENSP00000005340|dip:DIP-34433N|entrezgene/locuslink:1856(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:ogXRiOOp698mlPdAiFidYakMtI4559292	rogid:2Vdc8oRnT4Mz/j+EXQXrL3AszOc9606	intact-crc:7A4240FE9BC5B1AB|rigid:6vhH6nB5Hy1JS8ihA9K04mjJlK4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P54784	uniprotkb:Q96EY1-3	intact:EBI-12568|uniprotkb:D6VZA8|ensemblfungi:YML065W	intact:EBI-11526226|ensembl:ENSP00000393970	psi-mi:orc1_yeast(display_long)|uniprotkb:ORC1(gene name)|psi-mi:ORC1(display_short)|uniprotkb:YML065W(locus name)|uniprotkb:Origin recognition complex 120 kDa subunit(gene name synonym)	psi-mi:q96ey1-3(display_long)|uniprotkb:DnaJ protein Tid-1(gene name synonym)|uniprotkb:HCA57(gene name synonym)|uniprotkb:Hepatocellular carcinoma-associated antigen 57(gene name synonym)|uniprotkb:TID1(gene name synonym)|uniprotkb:Tumorous imaginal discs protein Tid56 homolog(gene name synonym)|uniprotkb:DNAJA3(gene name)|psi-mi:DNAJA3(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11544456|imex:IM-24995-2332	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:6WGG|rcsb pdb:6WGI|rcsb pdb:7MCA|reactome:R-SCE-68616|rcsb pdb:6WGC|reactome:R-SCE-68949|reactome:R-SCE-68962|ensemblfungi:YML065W(gene)|ensemblfungi:YML065W_mRNA(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031491"(nucleosome binding)|go:"GO:0033314"(mitotic DNA replication checkpoint signaling)|go:"GO:0043007"(maintenance of rDNA)|go:"GO:0046872"(metal ion binding)|interpro:IPR001025(Bromo adjacent region)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR020793|interpro:IPR027417|interpro:IPR041083|interpro:IPR043151|rcsb pdb:1M4Z|rcsb pdb:1ZBX|rcsb pdb:1ZHI|rcsb pdb:5V8F|rcsb pdb:5ZR1|rcsb pdb:6OM3|rcsb pdb:6RQC|refseq:NP_013646.1|sgd:S000004530|dip:DIP-2284N|mint:P54784|sgd:YML065W(identity)	intact:EBI-356767(isoform-parent)|ensembl:ENSG00000103423(gene)|ensembl:ENST00000431375(transcript)|uniprotkb:Q96EY1-3(isoform-parent)|entrezgene/locuslink:9093(identity)	-	crc64:BDAA9D3E40B4B76A	isoform-comment:"Ref.3 (BAG58345) sequence is in conflict in position: 33:Y->H."	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:ZTOvWqU+Rxwll7cRwOUsRqJC08M559292	rogid:nMH4IaOZYO5w5bh+cdX4LoPSisc9606	intact-crc:E53DFE65AE1124A5|rigid:uyQdY0emWwd3M6pHBgtdiMY4lq0	false	-	sufficient binding region:60-300	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UMX0	uniprotkb:P61829	intact:EBI-741480|uniprotkb:Q8IXS9|uniprotkb:Q8N2Q3|uniprotkb:Q9H0T8|uniprotkb:Q9H3R4|uniprotkb:Q9HAZ5|intact:EBI-28967608|ensembl:ENSP00000365576|uniprotkb:Q5T6J5|uniprotkb:Q5T6J9|uniprotkb:A0A024R284	intact:EBI-9016907|uniprotkb:P00841|uniprotkb:Q37750|uniprotkb:A0A0A7P075|ensemblfungi:Q0130	psi-mi:ubql1_human(display_long)|uniprotkb:Protein linking IAP with cytoskeleton 1(gene name synonym)|uniprotkb:UBQLN1(gene name)|psi-mi:UBQLN1(display_short)|uniprotkb:DA41(gene name synonym)|uniprotkb:PLIC1(gene name synonym)	psi-mi:atp9_yeast(display_long)|uniprotkb:OLI1(gene name)|psi-mi:OLI1(display_short)|uniprotkb:ATP9(gene name synonym)|uniprotkb:Lipid-binding protein(gene name synonym)|uniprotkb:OLI3(gene name synonym)|uniprotkb:Oligomycin resistance protein 1(gene name synonym)|uniprotkb:PHO2(gene name synonym)|uniprotkb:Q0130(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11544543|imex:IM-24995-2341	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000257468|ensembl:ENSP00000257468|ensembl:ENSP00000365576|ensembl:ENSG00000135018(gene)|ensembl:ENST00000376395(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000502"(proteasome complex)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016235"(aggresome)|go:"GO:0016236"(macroautophagy)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0019900"(kinase binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035973"(aggrephagy)|go:"GO:0042802"(identical protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0097352"(autophagosome maturation)|go:"GO:1901340"(negative regulation of store-operated calcium channel activity)|go:"GO:1902175"(regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)|interpro:IPR000626(Ubiquitin)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR028430|interpro:IPR029071|mint:Q9UMX0|rcsb pdb:2JY5|rcsb pdb:2JY6|rcsb pdb:2KLC|reactome:R-HSA-8856825|refseq:NP_038466.2|refseq:NP_444295.1|dip:DIP-41629N|entrezgene/locuslink:29979(identity)	reactome:R-SCE-163210|reactome:R-SCE-8949613|refseq:NP_009319.1|sgd:S000007274|refseq:YP_009144710.1|ensemblfungi:Q0130(gene)|ensemblfungi:Q0130_mRNA(transcript)|go:"GO:0000276"("mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)")|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005829"(cytosol)|go:"GO:0008289"(lipid binding)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045263"("proton-transporting ATP synthase complex, coupling factor F(o)")|interpro:IPR000454(ATPase, F0 complex, subunit C)|interpro:IPR002379(ATPase, F0/V0 complex, subunit C)|interpro:IPR020537|interpro:IPR035921|interpro:IPR038662|rcsb pdb:2WPD|rcsb pdb:2XOK|rcsb pdb:3U2F|rcsb pdb:3U2Y|rcsb pdb:3U32|rcsb pdb:3UD0|rcsb pdb:3ZRY|rcsb pdb:4B2Q|rcsb pdb:4F4S|rcsb pdb:5BPS|rcsb pdb:5BQ6|rcsb pdb:5BQA|rcsb pdb:5BQJ|rcsb pdb:6B2Z|rcsb pdb:6B8H|rcsb pdb:6CP3|rcsb pdb:6CP5|rcsb pdb:6CP6|rcsb pdb:6CP7|rcsb pdb:6WTD|dip:DIP-3041N|sgd:Q0130(identity)	-	-	crc64:82B4477D6F75D758	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:nCFfZbGCTvRYaXhQ4R99XblslvM9606	rogid:z8+f6dq67i096v23FKqgqAt3Ba4559292	intact-crc:61AABB2056469DF4|rigid:jygzs/RZYkYaXr521b/0wzywZAs	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P60010	uniprotkb:P63279	intact:EBI-2169|uniprotkb:P02579|uniprotkb:Q9P3X6|uniprotkb:Q9P3X7|uniprotkb:D6VTJ1|ensemblfungi:YFL039C	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	psi-mi:act_yeast(display_long)|uniprotkb:ACT1(gene name)|psi-mi:ACT1(display_short)|uniprotkb:ABY1(gene name synonym)|uniprotkb:END7(gene name synonym)|uniprotkb:YFL039C(locus name)	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11544534|imex:IM-24995-2340	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_116614.1|sgd:S000001855|dip:DIP-310N|mint:P60010|ensemblfungi:YFL039C(gene)|ensemblfungi:YFL039C_mRNA(transcript)|go:"GO:0000011"(vacuole inheritance)|go:"GO:0000142"(cellular bud neck contractile ring)|go:"GO:0000812"(Swr1 complex)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005524"(ATP binding)|go:"GO:0005884"(actin filament)|go:"GO:0006281"(DNA repair)|go:"GO:0006897"(endocytosis)|go:"GO:0009306"(protein secretion)|go:"GO:0016573"(histone acetylation)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030476"(ascospore wall assembly)|go:"GO:0030479"(actin cortical patch)|go:"GO:0031011"(Ino80 complex)|go:"GO:0032432"(actin filament bundle)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:1902404"(mitotic actomyosin contractile ring contraction)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|rcsb pdb:1YAG|rcsb pdb:1YVN|rcsb pdb:5NBL|rcsb pdb:5NBM|rcsb pdb:5NBN|rcsb pdb:5Y81|reactome:R-SCE-114608|reactome:R-SCE-190873|reactome:R-SCE-196025|reactome:R-SCE-2029482|reactome:R-SCE-5626467|reactome:R-SCE-5663213|reactome:R-SCE-8856828|reactome:R-SCE-8980692|reactome:R-SCE-9013026|sgd:YFL039C(identity)	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N|entrezgene/locuslink:7329(identity)	-	crc64:87AC19B0B0BC9E71	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:yfgwiWq/Y0HviACqgjjUugpEKLw559292	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	intact-crc:1C4752A080C86ECD|rigid:19emcZCbYXAS9jiEmSlPqcW4P9M	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P60010	uniprotkb:P63261	intact:EBI-2169|uniprotkb:P02579|uniprotkb:Q9P3X6|uniprotkb:Q9P3X7|uniprotkb:D6VTJ1|ensemblfungi:YFL039C	intact:EBI-351292|uniprotkb:P02571|uniprotkb:P14104|uniprotkb:P99022|uniprotkb:Q5U032|uniprotkb:Q96E67|uniprotkb:A8K7C2|ensembl:ENSP00000505060|ensembl:ENSP00000505193|ensembl:ENSP00000505235|ensembl:ENSP00000506126|ensembl:ENSP00000506201|ensembl:ENSP00000506253|ensembl:ENSP00000458162|ensembl:ENSP00000458435|ensembl:ENSP00000459119|ensembl:ENSP00000459124|ensembl:ENSP00000460464|ensembl:ENSP00000460660|ensembl:ENSP00000461672|ensembl:ENSP00000466346|ensembl:ENSP00000477968	psi-mi:act_yeast(display_long)|uniprotkb:ACT1(gene name)|psi-mi:ACT1(display_short)|uniprotkb:ABY1(gene name synonym)|uniprotkb:END7(gene name synonym)|uniprotkb:YFL039C(locus name)	psi-mi:actg_human(display_long)|uniprotkb:ACTG1(gene name)|psi-mi:ACTG1(display_short)|uniprotkb:ACTG(gene name synonym)|uniprotkb:Gamma-actin(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11544524|imex:IM-24995-2339	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_116614.1|sgd:S000001855|dip:DIP-310N|mint:P60010|ensemblfungi:YFL039C(gene)|ensemblfungi:YFL039C_mRNA(transcript)|go:"GO:0000011"(vacuole inheritance)|go:"GO:0000142"(cellular bud neck contractile ring)|go:"GO:0000812"(Swr1 complex)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005524"(ATP binding)|go:"GO:0005884"(actin filament)|go:"GO:0006281"(DNA repair)|go:"GO:0006897"(endocytosis)|go:"GO:0009306"(protein secretion)|go:"GO:0016573"(histone acetylation)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030476"(ascospore wall assembly)|go:"GO:0030479"(actin cortical patch)|go:"GO:0031011"(Ino80 complex)|go:"GO:0032432"(actin filament bundle)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:1902404"(mitotic actomyosin contractile ring contraction)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|rcsb pdb:1YAG|rcsb pdb:1YVN|rcsb pdb:5NBL|rcsb pdb:5NBM|rcsb pdb:5NBN|rcsb pdb:5Y81|reactome:R-SCE-114608|reactome:R-SCE-190873|reactome:R-SCE-196025|reactome:R-SCE-2029482|reactome:R-SCE-5626467|reactome:R-SCE-5663213|reactome:R-SCE-8856828|reactome:R-SCE-8980692|reactome:R-SCE-9013026|sgd:YFL039C(identity)	refseq:NP_001186883.1|refseq:NP_001605.1|ensembl:ENST00000570382(transcript)|ensembl:ENSG00000184009(gene)|ensembl:ENST00000571721(transcript)|ensembl:ENST00000573283(transcript)|ensembl:ENST00000575087(transcript)|ensembl:ENST00000575659(transcript)|ensembl:ENST00000575842(transcript)|ensembl:ENST00000575994(transcript)|ensembl:ENST00000576544(transcript)|ensembl:ENST00000615544(transcript)|ensembl:ENST00000679480(transcript)|ensembl:ENST00000679778(transcript)|ensembl:ENST00000680227(transcript)|ensembl:ENST00000680727(transcript)|ensembl:ENST00000681052(transcript)|ensembl:ENST00000681842(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0001895"(retina homeostasis)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005522"(profilin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0030016"(myofibril)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031941"(filamentous actin)|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0044305"(calyx of Held)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0051492"(regulation of stress fiber assembly)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070527"(platelet aggregation)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0072562"(blood microparticle)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0097433"(dense body)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098973"(structural constituent of postsynaptic actin cytoskeleton)|go:"GO:0120192"(tight junction assembly)|go:"GO:0120220"(basal body patch)|go:"GO:0150111"(regulation of transepithelial transport)|go:"GO:1902396"(protein localization to bicellular tight junction)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P63261|rcsb pdb:5JLH|rcsb pdb:6CXI|rcsb pdb:6CXJ|rcsb pdb:6G2T|rcsb pdb:6V62|rcsb pdb:6V63|rcsb pdb:6WK1|rcsb pdb:6WK2|reactome:R-HSA-1445148|reactome:R-HSA-190873|reactome:R-HSA-196025|reactome:R-HSA-2029482|reactome:R-HSA-3928662|reactome:R-HSA-3928665|reactome:R-HSA-418990|reactome:R-HSA-437239|reactome:R-HSA-4420097|reactome:R-HSA-445095|reactome:R-HSA-446353|reactome:R-HSA-5626467|reactome:R-HSA-5663213|reactome:R-HSA-5663220|reactome:R-HSA-5674135|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8856828|reactome:R-HSA-9013418|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9662360|reactome:R-HSA-9662361|reactome:R-HSA-9664422|entrezgene/locuslink:71(identity)	-	crc64:87AC19B0B0BC9E71	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:yfgwiWq/Y0HviACqgjjUugpEKLw559292	rogid:B2OOsE06lTfo90H3g8tlmUJQ7cY9606	intact-crc:D215472304058C89|rigid:RZtrroqUOrg1ChAbVxQhz5fMr1w	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P60010	uniprotkb:P60709	intact:EBI-2169|uniprotkb:P02579|uniprotkb:Q9P3X6|uniprotkb:Q9P3X7|uniprotkb:D6VTJ1|ensemblfungi:YFL039C	intact:EBI-353944|uniprotkb:P02570|uniprotkb:P70514|uniprotkb:P99021|uniprotkb:Q11211|uniprotkb:Q64316|uniprotkb:Q75MN2|uniprotkb:Q96B34|uniprotkb:Q96HG5|ensembl:ENSP00000494269|ensembl:ENSP00000494750|ensembl:ENSP00000495995|ensembl:ENSP00000501862|ensembl:ENSP00000502821	psi-mi:act_yeast(display_long)|uniprotkb:ACT1(gene name)|psi-mi:ACT1(display_short)|uniprotkb:ABY1(gene name synonym)|uniprotkb:END7(gene name synonym)|uniprotkb:YFL039C(locus name)	psi-mi:actb_human(display_long)|uniprotkb:ACTB(gene name)|psi-mi:ACTB(display_short)|uniprotkb:Beta-actin(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11544514|imex:IM-24995-2338	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_116614.1|sgd:S000001855|dip:DIP-310N|mint:P60010|ensemblfungi:YFL039C(gene)|ensemblfungi:YFL039C_mRNA(transcript)|go:"GO:0000011"(vacuole inheritance)|go:"GO:0000142"(cellular bud neck contractile ring)|go:"GO:0000812"(Swr1 complex)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005524"(ATP binding)|go:"GO:0005884"(actin filament)|go:"GO:0006281"(DNA repair)|go:"GO:0006897"(endocytosis)|go:"GO:0009306"(protein secretion)|go:"GO:0016573"(histone acetylation)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030476"(ascospore wall assembly)|go:"GO:0030479"(actin cortical patch)|go:"GO:0031011"(Ino80 complex)|go:"GO:0032432"(actin filament bundle)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:1902404"(mitotic actomyosin contractile ring contraction)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|rcsb pdb:1YAG|rcsb pdb:1YVN|rcsb pdb:5NBL|rcsb pdb:5NBM|rcsb pdb:5NBN|rcsb pdb:5Y81|reactome:R-SCE-114608|reactome:R-SCE-190873|reactome:R-SCE-196025|reactome:R-SCE-2029482|reactome:R-SCE-5626467|reactome:R-SCE-5663213|reactome:R-SCE-8856828|reactome:R-SCE-8980692|reactome:R-SCE-9013026|sgd:YFL039C(identity)	refseq:NP_001092.1|ensembl:ENSG00000075624(gene)|ensembl:ENST00000493945(transcript)|ensembl:ENST00000642480(transcript)|ensembl:ENST00000646664(transcript)|ensembl:ENST00000674681(transcript)|ensembl:ENST00000675515(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000785"(chromatin)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0001895"(retina homeostasis)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007409"(axonogenesis)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019894"(kinesin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0022898"(regulation of transmembrane transporter activity)|go:"GO:0030027"(lamellipodium)|go:"GO:0030424"(axon)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0030957"(Tat protein binding)|go:"GO:0031982"(vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034333"(adherens junction assembly)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043044"|go:"GO:0043296"(apical junction complex)|go:"GO:0044305"(calyx of Held)|go:"GO:0045176"(apical protein localization)|go:"GO:0045202"(synapse)|go:"GO:0048156"(tau protein binding)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048870"(cell motility)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051621"(regulation of norepinephrine uptake)|go:"GO:0051623"(positive regulation of norepinephrine uptake)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070160"(tight junction)|go:"GO:0070527"(platelet aggregation)|reactome:R-HSA-4420097|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0072562"(blood microparticle)|go:"GO:0072749"(cellular response to cytochalasin B)|go:"GO:0097433"(dense body)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098973"(structural constituent of postsynaptic actin cytoskeleton)|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0150111"(regulation of transepithelial transport)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P60709|rcsb pdb:3BYH|rcsb pdb:3D2U|rcsb pdb:3J82|rcsb pdb:3LUE|rcsb pdb:6ANU|rcsb pdb:6ICT|rcsb pdb:6ICV|rcsb pdb:6LTJ|rcsb pdb:6MBJ|rcsb pdb:6MBK|rcsb pdb:6MBL|rcsb pdb:6NBW|rcsb pdb:6OX0|rcsb pdb:6OX1|rcsb pdb:6OX2|rcsb pdb:6OX3|rcsb pdb:6OX4|rcsb pdb:6OX5|rcsb pdb:6V62|rcsb pdb:6V63|rcsb pdb:6WK1|rcsb pdb:6WK2|rcsb pdb:7AS4|reactome:R-HSA-1445148|reactome:R-HSA-190873|reactome:R-HSA-196025|reactome:R-HSA-2029482|reactome:R-HSA-3214847|reactome:R-HSA-389957|reactome:R-HSA-390450|reactome:R-HSA-3928662|reactome:R-HSA-3928665|reactome:R-HSA-418990|reactome:R-HSA-437239|reactome:R-HSA-446353|reactome:R-HSA-5250924|reactome:R-HSA-5626467|reactome:R-HSA-5663213|reactome:R-HSA-5663220|reactome:R-HSA-5674135|reactome:R-HSA-5689603|reactome:R-HSA-5696394|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8856828|reactome:R-HSA-9035034|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9662360|reactome:R-HSA-9662361|reactome:R-HSA-9664422|reactome:R-HSA-983231|reactome:R-HSA-445095|dip:DIP-29686N|entrezgene/locuslink:60(identity)	-	crc64:87AC19B0B0BC9E71	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:yfgwiWq/Y0HviACqgjjUugpEKLw559292	rogid:Hoge1B8Pn56kvbNTpkSLsQuHwRc9606	intact-crc:180CE0B6E95AEDD3|rigid:YgERg3OzIJM/7XW/p2uhHxVz360	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40123	uniprotkb:P60010	intact:EBI-1051165|uniprotkb:Q6IAY2|uniprotkb:B2R5Y3|intact:EBI-11045298|uniprotkb:B7Z1C4|uniprotkb:B7Z214|ensembl:ENSP00000229922	intact:EBI-2169|uniprotkb:P02579|uniprotkb:Q9P3X6|uniprotkb:Q9P3X7|uniprotkb:D6VTJ1|ensemblfungi:YFL039C	psi-mi:cap2_human(display_long)|uniprotkb:CAP2(gene name)|psi-mi:CAP2(display_short)	psi-mi:act_yeast(display_long)|uniprotkb:ACT1(gene name)|psi-mi:ACT1(display_short)|uniprotkb:ABY1(gene name synonym)|uniprotkb:END7(gene name synonym)|uniprotkb:YFL039C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11544505|imex:IM-24995-2337	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006357.1|ensembl:ENSG00000112186(gene)|ensembl:ENST00000229922(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007165"(signal transduction)|go:"GO:0007190"(activation of adenylate cyclase activity)|go:"GO:0008179"(adenylate cyclase binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0042802"(identical protein binding)|go:"GO:0045761"(regulation of adenylate cyclase activity)|interpro:IPR001837(Adenylate cyclase-associated CAP)|interpro:IPR006599(CARP motif)|interpro:IPR013912(Adenylate cyclase-associated CAP,  C-terminal)|interpro:IPR013992(Adenylate cyclase-associated CAP, N-terminal)|interpro:IPR016098(Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal)|interpro:IPR017901|interpro:IPR018106|interpro:IPR028417|interpro:IPR028418|interpro:IPR036222|interpro:IPR036223|reactome:R-HSA-428890|go:"GO:0005886"(plasma membrane)|entrezgene/locuslink:10486(identity)	refseq:NP_116614.1|sgd:S000001855|dip:DIP-310N|mint:P60010|ensemblfungi:YFL039C(gene)|ensemblfungi:YFL039C_mRNA(transcript)|go:"GO:0000011"(vacuole inheritance)|go:"GO:0000142"(cellular bud neck contractile ring)|go:"GO:0000812"(Swr1 complex)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005524"(ATP binding)|go:"GO:0005884"(actin filament)|go:"GO:0006281"(DNA repair)|go:"GO:0006897"(endocytosis)|go:"GO:0009306"(protein secretion)|go:"GO:0016573"(histone acetylation)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030476"(ascospore wall assembly)|go:"GO:0030479"(actin cortical patch)|go:"GO:0031011"(Ino80 complex)|go:"GO:0032432"(actin filament bundle)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:1902404"(mitotic actomyosin contractile ring contraction)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|rcsb pdb:1YAG|rcsb pdb:1YVN|rcsb pdb:5NBL|rcsb pdb:5NBM|rcsb pdb:5NBN|rcsb pdb:5Y81|reactome:R-SCE-114608|reactome:R-SCE-190873|reactome:R-SCE-196025|reactome:R-SCE-2029482|reactome:R-SCE-5626467|reactome:R-SCE-5663213|reactome:R-SCE-8856828|reactome:R-SCE-8980692|reactome:R-SCE-9013026|sgd:YFL039C(identity)	-	-	crc64:87AC19B0B0BC9E71	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:+B9t0sirXq7xJD3kZIlab7KBR9Y9606	rogid:yfgwiWq/Y0HviACqgjjUugpEKLw559292	intact-crc:BAB43F5EA7D27DB2|rigid:/eNgyaKHZ+vJNnJqoJIyS8i8+6s	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8IYF3-3	uniprotkb:P87108	intact:EBI-11523345|ensembl:ENSP00000363453	intact:EBI-9115|ensemblfungi:YHR005C-A|uniprotkb:D3DKU9	psi-mi:q8iyf3-3(display_long)|uniprotkb:TEX11(gene name)|psi-mi:TEX11(display_short)|uniprotkb:Protein ZIP4 homolog(gene name synonym)|uniprotkb:ZIP4(gene name synonym)	psi-mi:tim10_yeast(display_long)|uniprotkb:MRS11(gene name synonym)|uniprotkb:YHR005BC(orf name)|uniprotkb:YHR005C-A(locus name)|uniprotkb:TIM10(gene name)|psi-mi:TIM10(display_short)|uniprotkb:Mitochondrial intermembrane protein MRS11(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11544581|imex:IM-24995-2345	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000120498(gene)|ensembl:ENST00000374333(transcript)|intact:EBI-742397(isoform-parent)|uniprotkb:Q8IYF3-3(isoform-parent)|entrezgene/locuslink:56159(identity)	ensemblfungi:YHR005C-A(gene)|ensemblfungi:YHR005C-A_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0042719"(mitochondrial intermembrane space protein transporter complex)|go:"GO:0045039"(protein insertion into mitochondrial inner membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0140318"(protein transporter activity)|interpro:IPR004217(Zinc finger, Tim10/DDP-type)|interpro:IPR027100|interpro:IPR035427|rcsb pdb:3DXR|rcsb pdb:6LO8|reactome:R-SCE-1268020|refseq:NP_011869.1|sgd:S000003530|dip:DIP-1141N|mint:P87108|sgd:YHR005C-A(identity)	-	-	crc64:70DD4764B944FF17	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:PUAMFmnm5ZV2rnJ1rhm9ZeRCixg9606	rogid:3AGstULCT5EBmHEk0EGsz9Rk9YA559292	intact-crc:D41D34F45027FFE8|rigid:qwPzymulS4vtLWgly/ubvTgvMCU	false	sufficient binding region:9-925	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P87108	uniprotkb:P43356	intact:EBI-9115|ensemblfungi:YHR005C-A|uniprotkb:D3DKU9	intact:EBI-5650739|uniprotkb:A8K328|uniprotkb:Q32NC6|ensembl:ENSP00000333487|ensembl:ENSP00000359316|ensembl:ENSP00000469919|ensembl:ENSP00000470872|ensembl:ENSP00000480491|ensembl:ENSP00000480738|ensembl:ENSP00000484290|ensembl:ENSP00000485391|ensembl:ENSP00000485541|ensembl:ENSP00000507594|ensembl:ENSP00000507899	psi-mi:tim10_yeast(display_long)|uniprotkb:MRS11(gene name synonym)|uniprotkb:YHR005BC(orf name)|uniprotkb:YHR005C-A(locus name)|uniprotkb:TIM10(gene name)|psi-mi:TIM10(display_short)|uniprotkb:Mitochondrial intermembrane protein MRS11(gene name synonym)	psi-mi:maga2_human(display_long)|uniprotkb:MAGEA2(gene name)|psi-mi:MAGEA2(display_short)|uniprotkb:MAGEA2B(gene name)|psi-mi:MAGEA2B(display_short)|uniprotkb:MAGE2(gene name synonym)|uniprotkb:MAGEA2A(gene name synonym)|uniprotkb:MAGE2(gene name synonym)|uniprotkb:MAGEA2(gene name synonym)|uniprotkb:Cancer/testis antigen 1.2(gene name synonym)|uniprotkb:MAGE-2 antigen(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11544572|imex:IM-24995-2344	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YHR005C-A(gene)|ensemblfungi:YHR005C-A_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0042719"(mitochondrial intermembrane space protein transporter complex)|go:"GO:0045039"(protein insertion into mitochondrial inner membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0140318"(protein transporter activity)|interpro:IPR004217(Zinc finger, Tim10/DDP-type)|interpro:IPR027100|interpro:IPR035427|rcsb pdb:3DXR|rcsb pdb:6LO8|reactome:R-SCE-1268020|refseq:NP_011869.1|sgd:S000003530|dip:DIP-1141N|mint:P87108|sgd:YHR005C-A(identity)	refseq:NP_001269430.1|refseq:NP_001269431.1|refseq:NP_001269433.1|refseq:NP_001269434.1|refseq:NP_001308329.1|refseq:NP_001308330.1|refseq:NP_001308331.1|refseq:NP_001308332.1|refseq:NP_001308333.1|refseq:NP_005352.1|refseq:NP_705692.1|refseq:NP_786884.1|refseq:NP_786885.1|dip:DIP-61231N|refseq:XP_016884895.1|refseq:XP_016885008.1|ensembl:ENSG00000183305(gene)|ensembl:ENSG00000268606(gene)|ensembl:ENST00000331220(transcript)|ensembl:ENST00000370293(transcript)|ensembl:ENST00000595583(transcript)|ensembl:ENST00000598543(transcript)|ensembl:ENST00000611557(transcript)|ensembl:ENST00000611674(transcript)|ensembl:ENST00000620710(transcript)|ensembl:ENST00000623438(transcript)|ensembl:ENST00000623806(transcript)|ensembl:ENST00000682532(transcript)|ensembl:ENST00000684311(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0016605"(PML body)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0033234"(negative regulation of protein sumoylation)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0044257"(cellular protein catabolic process)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0072331"(signal transduction by p53 class mediator)|go:"GO:0090398"(cellular senescence)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901984"(negative regulation of protein acetylation)|interpro:IPR002190(MAGE protein)|interpro:IPR021072|interpro:IPR030103|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|entrezgene/locuslink:266740(identity)	-	crc64:70DD4764B944FF17	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:3AGstULCT5EBmHEk0EGsz9Rk9YA559292	rogid:aYv4+irEk9vGE2f3yZQR8hCQGec9606	intact-crc:4D03B3FE84E0D463|rigid:m2ZGLKKYf+pz/TOU270gTTuSVIU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P69851	uniprotkb:Q9UPT5-1	intact:EBI-975389|uniprotkb:D6VSV2|ensemblfungi:YDR320C-A	intact:EBI-6251402|ensembl:ENSP00000468404	psi-mi:dad4_yeast(display_long)|uniprotkb:Outer kinetochore protein DAD4(gene name synonym)|uniprotkb:DUO1 and DAM1-interacting protein 4(gene name synonym)|uniprotkb:Helper of ASK1 protein 2(gene name synonym)|uniprotkb:DAD4(gene name)|psi-mi:DAD4(display_short)|uniprotkb:HSK2(gene name synonym)|uniprotkb:YDR320C-A(locus name)	psi-mi:q9upt5-1(display_long)|uniprotkb:EXOC7(gene name)|psi-mi:EXOC7(display_short)|uniprotkb:EXO70(gene name synonym)|uniprotkb:KIAA1067(gene name synonym)|uniprotkb:Exocyst complex component Exo70(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11544563|imex:IM-24995-2343	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YDR320C-A(gene)|ensemblfungi:YDR320C-A_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0008608"(attachment of spindle microtubules to kinetochore)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0042729"(DASH complex)|go:"GO:0051301"(cell division)|go:"GO:0051987"(positive regulation of attachment of spindle microtubules to kinetochore)|go:"GO:0072686"(mitotic spindle)|sgd:S000007604|interpro:IPR013959(DASH complex, subunit Dad4)|refseq:NP_710144.3|mint:P69851|sgd:YDR320C-A(identity)	ensembl:ENSG00000182473(gene)|ensembl:ENST00000589210(transcript)|intact:EBI-720048(isoform-parent)|uniprotkb:Q9UPT5-1(isoform-parent)|entrezgene/locuslink:23265(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:P+GXHuoP14//+W2vOt26MEdTBNo559292	rogid:CKIeTOGXIWrHA1Duuw7x1ycRPoc9606	intact-crc:F3C429F77850AF39|rigid:Dz3cuiQPy1CeDZl+jtjPoiO0azk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P69851	uniprotkb:Q7Z6G3-2	intact:EBI-975389|uniprotkb:D6VSV2|ensemblfungi:YDR320C-A	intact:EBI-10172876|ensembl:ENSP00000457354|intact:EBI-14062040	psi-mi:dad4_yeast(display_long)|uniprotkb:Outer kinetochore protein DAD4(gene name synonym)|uniprotkb:DUO1 and DAM1-interacting protein 4(gene name synonym)|uniprotkb:Helper of ASK1 protein 2(gene name synonym)|uniprotkb:DAD4(gene name)|psi-mi:DAD4(display_short)|uniprotkb:HSK2(gene name synonym)|uniprotkb:YDR320C-A(locus name)	psi-mi:q7z6g3-2(display_long)|uniprotkb:EFCBP2(gene name synonym)|uniprotkb:Neuronal calcium-binding protein 2(gene name synonym)|uniprotkb:Synaptotagmin-interacting protein 2(gene name synonym)|uniprotkb:NECAB2(gene name)|psi-mi:NECAB2(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11544552|imex:IM-24995-2342	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YDR320C-A(gene)|ensemblfungi:YDR320C-A_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0008608"(attachment of spindle microtubules to kinetochore)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0042729"(DASH complex)|go:"GO:0051301"(cell division)|go:"GO:0051987"(positive regulation of attachment of spindle microtubules to kinetochore)|go:"GO:0072686"(mitotic spindle)|sgd:S000007604|interpro:IPR013959(DASH complex, subunit Dad4)|refseq:NP_710144.3|mint:P69851|sgd:YDR320C-A(identity)	ensembl:ENSG00000103154(gene)|ensembl:ENST00000565691(transcript)|uniprotkb:Q7Z6G3-2(isoform-parent)|intact:EBI-950070(isoform-parent)|entrezgene/locuslink:54550(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:P+GXHuoP14//+W2vOt26MEdTBNo559292	rogid:4S7oIx6h+mKzV3EPxqcfMNqaNko9606	intact-crc:91C3E84D2EBB22C3|rigid:XeYySTq6AMDc79CirC718x56X1k	false	-	sufficient binding region:65-303	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P89886	uniprotkb:O43583	intact:EBI-33141|uniprotkb:D3DLQ4|ensemblfungi:YER007C-A	intact:EBI-716083|uniprotkb:Q9H3U6|uniprotkb:Q9UKZ0|ensembl:ENSP00000280557	psi-mi:tma20_yeast(display_long)|uniprotkb:TMA20(gene name)|psi-mi:TMA20(display_short)|uniprotkb:YER007C-A(locus name)	psi-mi:denr_human(display_long)|uniprotkb:Protein DRP1(gene name synonym)|uniprotkb:Smooth muscle cell-associated protein 3(gene name synonym)|uniprotkb:DENR(gene name)|psi-mi:DENR(display_short)|uniprotkb:DRP1(gene name synonym)|uniprotkb:H14(orf name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11544612|imex:IM-24995-2348	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002957|refseq:NP_010923.3|mint:P89886|dip:DIP-1841N|ensemblfungi:YER007C-A(gene)|ensemblfungi:YER007C-A_mRNA(transcript)|go:"GO:0001731"(formation of translation preinitiation complex)|go:"GO:0002188"(translation reinitiation)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0042254"(ribosome biogenesis)|interpro:IPR002478(PUA)|interpro:IPR004521(Uncharacterized domain 2)|interpro:IPR015947(PUA-like)|interpro:IPR016437(Translation machinery-associated RNA binding protein, predicted)|interpro:IPR041366|sgd:YER007C-A(identity)	refseq:NP_003668.2|go:"GO:0075522"(IRES-dependent viral translational initiation)|interpro:IPR001950(Translation initiation factor SUI1)|interpro:IPR005873(Density-regulated protein DRP1)|interpro:IPR036877|go:"GO:0032790"(ribosome disassembly)|mint:O43583|rcsb pdb:5ONS|rcsb pdb:5VYC|rcsb pdb:6MS4|rcsb pdb:6VPQ|rcsb pdb:6VPR|ensembl:ENSG00000139726(gene)|ensembl:ENST00000280557(transcript)|go:"GO:0001731"(formation of translation preinitiation complex)|go:"GO:0002188"(translation reinitiation)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|entrezgene/locuslink:8562(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:vBHXl1594jcHQvXHu/MCy4G6U4c559292	rogid:pZLEnnYWNEai+gZ/jD+Rt9B6j2E9606	intact-crc:74C08AA8ACCCF47F|rigid:lI9/Vn8gtSU8OSadw26o/6OpIBo	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P89105	uniprotkb:Q5VWN6	intact:EBI-5283|uniprotkb:O14409|uniprotkb:Q07332|uniprotkb:Q08292|uniprotkb:D6W1S4|ensemblfungi:YOL145C	intact:EBI-745958|uniprotkb:Q2YD91|uniprotkb:Q5VWN5|uniprotkb:Q6ZRQ8|uniprotkb:Q8IVG4|uniprotkb:Q9BUZ7|uniprotkb:Q9H5J9|uniprotkb:Q9H7A4|uniprotkb:Q9H996|uniprotkb:Q9NXA1|intact:EBI-28974916|ensembl:ENSP00000328426	psi-mi:ctr9_yeast(display_long)|uniprotkb:CTR9(gene name)|psi-mi:CTR9(display_short)|uniprotkb:CDP1(gene name synonym)|uniprotkb:Cln three-requiring protein 9(gene name synonym)|uniprotkb:Centromere-binding factor 1-dependent protein 1(gene name synonym)|uniprotkb:YOL145C(locus name)	psi-mi:taso2_human(display_long)|uniprotkb:TASOR2(gene name)|psi-mi:TASOR2(display_short)|uniprotkb:C10orf18(gene name synonym)|uniprotkb:FAM208B(gene name synonym)|uniprotkb:KIAA2006(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11544601|imex:IM-24995-2347	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014496.2|sgd:S000005505|dip:DIP-2814N|mint:P89105|ensemblfungi:YOL145C(gene)|ensemblfungi:YOL145C_mRNA(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001015"(snoRNA transcription by RNA polymerase II)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006362"(transcription elongation from RNA polymerase I promoter)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016570"(histone modification)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0031126"("sno(s)RNA 3'-end processing")|go:"GO:0031938"(obsolete regulation of chromatin silencing at telomere)|go:"GO:0035327"|go:"GO:0045142"(triplex DNA binding)|go:"GO:0051569"(regulation of histone H3-K4 methylation)|go:"GO:0060260"(regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0090262"(regulation of transcription-coupled nucleotide-excision repair)|go:"GO:1901525"(negative regulation of mitophagy)|go:"GO:1990269"(RNA polymerase II C-terminal domain phosphoserine binding)|go:"GO:2001165"(positive regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues)|go:"GO:2001173"(regulation of histone H2B conserved C-terminal lysine ubiquitination)|go:"GO:2001209"(positive regulation of transcription elongation from RNA polymerase I promoter)|go:"GO:2001255"(positive regulation of histone H3-K36 trimethylation)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR031101|rcsb pdb:5ZYP|reactome:R-SCE-674695|reactome:R-SCE-75955|sgd:YOL145C(identity)	refseq:NP_060252.4|ensembl:ENSP00000328426|refseq:XP_011517827.1|refseq:XP_016871852.1|refseq:XP_016871854.1|ensembl:ENSG00000108021(gene)|ensembl:ENST00000328090(transcript)|go:"GO:0005829"(cytosol)|interpro:IPR022168|interpro:IPR022188|mint:Q5VWN6|go:"GO:0005654"(nucleoplasm)|refseq:XP_005252532.1|refseq:XP_005252537.1|refseq:XP_005252538.1|refseq:XP_005252539.1|refseq:NP_001308712.1|refseq:NP_001308713.1|refseq:NP_001308714.1|entrezgene/locuslink:54906(identity)	-	crc64:F794ECBAD26D4820	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:85qAqldtQL8T7JBgNxrvAYtHhd0559292	rogid:mTRMzWB45dZojaB1ZrsaQRT48YQ9606	intact-crc:312DA1178645AD18|rigid:FxzaTQsvu4zvbC5gJ0sb6VL7IaU	false	-	sufficient binding region:1690-2430	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q14596-2	uniprotkb:P89105	intact:EBI-11081753|ensembl:ENSP00000467816	intact:EBI-5283|uniprotkb:O14409|uniprotkb:Q07332|uniprotkb:Q08292|uniprotkb:D6W1S4|ensemblfungi:YOL145C	psi-mi:q14596-2(display_long)|uniprotkb:NBR1(gene name)|psi-mi:NBR1(display_short)|uniprotkb:1A13B(gene name synonym)|uniprotkb:Cell migration-inducing gene 19 protein(gene name synonym)|uniprotkb:KIAA0049(gene name synonym)|uniprotkb:M17S2(gene name synonym)|uniprotkb:Membrane component chromosome 17 surface marker 2(gene name synonym)|uniprotkb:Neighbor of BRCA1 gene 1 protein(gene name synonym)|uniprotkb:Protein 1A1-3B(gene name synonym)|uniprotkb:MIG19(orf name)	psi-mi:ctr9_yeast(display_long)|uniprotkb:CTR9(gene name)|psi-mi:CTR9(display_short)|uniprotkb:CDP1(gene name synonym)|uniprotkb:Cln three-requiring protein 9(gene name synonym)|uniprotkb:Centromere-binding factor 1-dependent protein 1(gene name synonym)|uniprotkb:YOL145C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11544592|imex:IM-24995-2346	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-742698(isoform-parent)|ensembl:ENSG00000188554(gene)|ensembl:ENST00000589872(transcript)|uniprotkb:Q14596-2(isoform-parent)|entrezgene/locuslink:4077(identity)	refseq:NP_014496.2|sgd:S000005505|dip:DIP-2814N|mint:P89105|ensemblfungi:YOL145C(gene)|ensemblfungi:YOL145C_mRNA(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001015"(snoRNA transcription by RNA polymerase II)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006362"(transcription elongation from RNA polymerase I promoter)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016570"(histone modification)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0031126"("sno(s)RNA 3'-end processing")|go:"GO:0031938"(obsolete regulation of chromatin silencing at telomere)|go:"GO:0035327"|go:"GO:0045142"(triplex DNA binding)|go:"GO:0051569"(regulation of histone H3-K4 methylation)|go:"GO:0060260"(regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0090262"(regulation of transcription-coupled nucleotide-excision repair)|go:"GO:1901525"(negative regulation of mitophagy)|go:"GO:1990269"(RNA polymerase II C-terminal domain phosphoserine binding)|go:"GO:2001165"(positive regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues)|go:"GO:2001173"(regulation of histone H2B conserved C-terminal lysine ubiquitination)|go:"GO:2001209"(positive regulation of transcription elongation from RNA polymerase I promoter)|go:"GO:2001255"(positive regulation of histone H3-K36 trimethylation)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR031101|rcsb pdb:5ZYP|reactome:R-SCE-674695|reactome:R-SCE-75955|sgd:YOL145C(identity)	-	isoform-comment:No experimental confirmation available.	crc64:F794ECBAD26D4820	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:KrZKoabpN1yOvD3Bt6+CCN9Wv5g9606	rogid:85qAqldtQL8T7JBgNxrvAYtHhd0559292	intact-crc:64CEE0A853B0E751|rigid:LG3mv+dbVjN5SNCITI1CYwWPwyY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q01976	uniprotkb:G5E962	intact:EBI-2344265|uniprotkb:D6VQB0|ensemblfungi:YBR111C	intact:EBI-11525615|ensembl:ENSP00000328177	psi-mi:adpp_yeast(display_long)|uniprotkb:YSA1(gene name)|psi-mi:YSA1(display_short)|uniprotkb:ADP-ribose diphosphatase(gene name synonym)|uniprotkb:Adenosine diphosphoribose pyrophosphatase(gene name synonym)|uniprotkb:ADP-ribose phosphohydrolase(gene name synonym)|uniprotkb:YBR0907(orf name)|uniprotkb:YBR111C(locus name)	psi-mi:g5e962_human(display_long)|uniprotkb:hCG_1644200(orf name)|uniprotkb:MAGEA11(gene name)|psi-mi:MAGEA11(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11544659|imex:IM-24995-2353	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009669.1|sgd:S000000315|interpro:IPR020084|interpro:IPR000086(NUDIX hydrolase, core)|interpro:IPR015797(NUDIX)|reactome:R-SCE-2393930|ensemblfungi:YBR111C(gene)|ensemblfungi:YBR111C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006753"(nucleoside phosphate metabolic process)|go:"GO:0019693"(ribose phosphate metabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0047631"(ADP-ribose diphosphatase activity)|sgd:YBR111C(identity)	refseq:NP_001011544.1|ensembl:ENSG00000185247(gene)|ensembl:ENST00000333104(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016604"(nuclear body)|interpro:IPR002190(MAGE protein)|interpro:IPR021072|interpro:IPR030099|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|entrezgene/locuslink:4110(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:tpdVT9ttt/pL+UevSr0zW+rfyIc559292	rogid:sVB0aA6yibWUx/d2SE+pwpKKgtI9606	intact-crc:AFFE3461F16B834B|rigid:+oIfTL7Jn2G8+m/q4jryuXjkY8U	false	-	sufficient binding region:82-400	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UI14	uniprotkb:Q01590	intact:EBI-712367|ensembl:ENSP00000222008|uniprotkb:Q7Z4Y2|uniprotkb:Q9Y3R1	intact:EBI-16930|uniprotkb:D6VY28|ensemblfungi:YLR026C	psi-mi:praf1_human(display_long)|uniprotkb:PRA1 family protein 1(gene name synonym)|uniprotkb:RABAC1(gene name)|psi-mi:RABAC1(display_short)|uniprotkb:PRA1(gene name synonym)|uniprotkb:PRAF1(gene name synonym)	psi-mi:sed5_yeast(display_long)|uniprotkb:SED5(gene name)|psi-mi:SED5(display_short)|uniprotkb:YLR026C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11544650|imex:IM-24995-2352	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006414.2|ensembl:ENSG00000105404(gene)|ensembl:ENST00000222008(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0070064"(proline-rich region binding)|interpro:IPR004895(Prenylated rab acceptor PRA1)|mint:Q9UI14|entrezgene/locuslink:10567(identity)	refseq:NP_013126.1|sgd:S000004016|ensemblfungi:YLR026C(gene)|ensemblfungi:YLR026C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0006906"(vesicle fusion)|go:"GO:0090083"(regulation of inclusion body assembly)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|interpro:IPR021538|rcsb pdb:1MQS|rcsb pdb:1PD0|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|reactome:R-SCE-204005|reactome:R-SCE-5694530|reactome:R-SCE-6807878|reactome:R-SCE-6811438|reactome:R-SCE-9609523|go:"GO:0031201"(SNARE complex)|go:"GO:0048278"(vesicle docking)|go:"GO:0048280"(vesicle fusion with Golgi apparatus)|dip:DIP-2489N|mint:Q01590|sgd:YLR026C(identity)	-	-	crc64:B3192B57269A0B83	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:WS2rUY7yXRbR7pqWgfUCbnEiDbg9606	rogid:c+W+86qfjxcvWWJ9nMScyH5TjNA559292	intact-crc:C9D9AB67708394C4|rigid:RgVmkjyaRYAZv3poNv9+Q5mqOo4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q01590	uniprotkb:Q8N6L0	intact:EBI-16930|uniprotkb:D6VY28|ensemblfungi:YLR026C	intact:EBI-749265|uniprotkb:Q96MC3|ensembl:ENSP00000404220	psi-mi:sed5_yeast(display_long)|uniprotkb:SED5(gene name)|psi-mi:SED5(display_short)|uniprotkb:YLR026C(locus name)	psi-mi:kash5_human(display_long)|uniprotkb:KASH5(gene name)|psi-mi:KASH5(display_short)|uniprotkb:CCDC155(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 155(gene name synonym)|uniprotkb:KASH domain-containing protein 5(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11544641|imex:IM-24995-2351	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013126.1|sgd:S000004016|ensemblfungi:YLR026C(gene)|ensemblfungi:YLR026C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0006906"(vesicle fusion)|go:"GO:0090083"(regulation of inclusion body assembly)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|interpro:IPR021538|rcsb pdb:1MQS|rcsb pdb:1PD0|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|reactome:R-SCE-204005|reactome:R-SCE-5694530|reactome:R-SCE-6807878|reactome:R-SCE-6811438|reactome:R-SCE-9609523|go:"GO:0031201"(SNARE complex)|go:"GO:0048278"(vesicle docking)|go:"GO:0048280"(vesicle fusion with Golgi apparatus)|dip:DIP-2489N|mint:Q01590|sgd:YLR026C(identity)	refseq:NP_653289.3|ensembl:ENSG00000161609(gene)|ensembl:ENST00000447857(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034397"(telomere localization)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051225"(spindle assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0090172"(microtubule cytoskeleton organization involved in homologous chromosome segregation)|go:"GO:0090220"(chromosome localization to nuclear envelope involved in homologous chromosome segregation)|go:"GO:0090619"(meiotic spindle pole)|interpro:IPR011992(EF-Hand type)|interpro:IPR028168|interpro:IPR028170|interpro:IPR039508|mint:Q8N6L0|rcsb pdb:6R2I|rcsb pdb:6WMF|entrezgene/locuslink:147872(identity)	-	crc64:B3192B57269A0B83	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:c+W+86qfjxcvWWJ9nMScyH5TjNA559292	rogid:Wl9L7AcvDHCZuKjYLn8QgGIbZTc9606	intact-crc:65EAAD2A66EA05C0|rigid:Tz4PxmOiFDvWjE8O6ssbXUTVHDA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q01589	uniprotkb:O95994	intact:EBI-16917|uniprotkb:D6VS63|uniprotkb:Q6Q5U8|uniprotkb:Q8J057|uniprotkb:Q8J270|uniprotkb:Q8J271|uniprotkb:Q8J272|uniprotkb:Q8J273|uniprotkb:Q8J274|uniprotkb:Q8J275|ensemblfungi:YDR077W	intact:EBI-712648|ensembl:ENSP00000391490	psi-mi:sed1_yeast(display_long)|uniprotkb:SED1(gene name)|psi-mi:SED1(display_short)|uniprotkb:YDR077W(locus name)|uniprotkb:D4431(orf name)|uniprotkb:Glycoprotein GP260(gene name synonym)	psi-mi:agr2_human(display_long)|uniprotkb:Secreted cement gland protein XAG-2 homolog(gene name synonym)|uniprotkb:HPC8(gene name synonym)|uniprotkb:AG2(gene name synonym)|uniprotkb:UNQ515/PRO1030(orf name)|uniprotkb:AGR2(gene name)|psi-mi:AGR2(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11544632|imex:IM-24995-2350	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010362.3|sgd:S000002484|ensemblfungi:YDR077W(gene)|ensemblfungi:YDR077W_mRNA(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0005199"(structural constituent of cell wall)|go:"GO:0005576"(extracellular region)|go:"GO:0005739"(mitochondrion)|go:"GO:0005840"(ribosome)|go:"GO:0009277"(fungal-type cell wall)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0071944"(cell periphery)|interpro:IPR038843|dip:DIP-1613N|sgd:YDR077W(identity)	go:"GO:0005615"(extracellular space)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0042802"(identical protein binding)|go:"GO:0045742"(positive regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0048546"(digestive tract morphogenesis)|go:"GO:0048639"(positive regulation of developmental growth)|go:"GO:0060480"(lung goblet cell differentiation)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070254"(mucus secretion)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:1903896"(positive regulation of IRE1-mediated unfolded protein response)|go:"GO:1903899"(positive regulation of PERK-mediated unfolded protein response)|interpro:IPR036249|rcsb pdb:2LNS|rcsb pdb:2LNT|ensembl:ENSG00000106541(gene)|ensembl:ENST00000419304(transcript)|go:"GO:0002162"(dystroglycan binding)|go:"GO:0005154"(epidermal growth factor receptor binding)|refseq:NP_006399.1|refseq:XP_005249638.1|dip:DIP-48825N|entrezgene/locuslink:10551(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:4Oyb3fialIFuwCLzsRFRcTML3ng559292	rogid:E824a1MDXuGzk23ohjS7HAeEx5U9606	intact-crc:56AD1C7D2C8B7836|rigid:+Og9Ak04gZMAOLZ+h81rO514dHk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q00618	uniprotkb:O76083-2	intact:EBI-3573|uniprotkb:D6VWF1|ensemblfungi:YJL031C	intact:EBI-11524542|ensembl:ENSP00000335242	psi-mi:pgta_yeast(display_long)|uniprotkb:Geranylgeranyl transferase type II subunit alpha(gene name synonym)|uniprotkb:Type II protein geranyl-geranyltransferase subunit alpha(gene name synonym)|uniprotkb:PGGT(gene name synonym)|uniprotkb:YPT1/SEC4 proteins geranylgeranyltransferase subunit alpha(gene name synonym)|uniprotkb:GGTase-II-alpha(gene name synonym)|uniprotkb:BET4(gene name)|psi-mi:BET4(display_short)|uniprotkb:YJL031C(locus name)|uniprotkb:J1254(orf name)	psi-mi:o76083-2(display_long)|uniprotkb:PDE9A(gene name)|psi-mi:PDE9A(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11544621|imex:IM-24995-2349	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012503.2|sgd:S000003568|reactome:R-SCE-6803205|reactome:R-SCE-8873719|dip:DIP-4994N|ensemblfungi:YJL031C(gene)|ensemblfungi:YJL031C_mRNA(transcript)|go:"GO:0004663"(Rab geranylgeranyltransferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005777"(peroxisome)|go:"GO:0005829"(cytosol)|go:"GO:0005968"(Rab-protein geranylgeranyltransferase complex)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0018344"(protein geranylgeranylation)|go:"GO:0031267"(small GTPase binding)|interpro:IPR002088(Protein prenyltransferase, alpha subunit)|interpro:IPR032955|sgd:YJL031C(identity)	intact:EBI-742764(isoform-parent)|ensembl:ENSG00000160191(gene)|ensembl:ENST00000335512(transcript)|uniprotkb:O76083-2(isoform-parent)|entrezgene/locuslink:5152(identity)	-	crc64:A7C3E16C14DDD09C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:xjJwfQovYxV3BOkX1NVrOXxq/PM559292	rogid:nTzgeYGOwTM/7VJUgxSnlnDiCFo9606	intact-crc:7B7F95E1FD1268D2|rigid:w0s0D19GLkafzdPDwaSttgLhW14	false	sufficient binding region:38-327	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q02209	uniprotkb:Q9HCM9-2	intact:EBI-27066|uniprotkb:D6VX77|ensemblfungi:YKR011C	intact:EBI-11523450|ensembl:ENSP00000365847|ensembl:ENSP00000373095|ensembl:ENSP00000373097|ensembl:ENSP00000379797|ensembl:ENSP00000379800|ensembl:ENSP00000383486|ensembl:ENSP00000387445|ensembl:ENSP00000389198|ensembl:ENSP00000389852|ensembl:ENSP00000392130|ensembl:ENSP00000394353|ensembl:ENSP00000396986|ensembl:ENSP00000398956|ensembl:ENSP00000401071|ensembl:ENSP00000401184|ensembl:ENSP00000404340|ensembl:ENSP00000404904|ensembl:ENSP00000411582|ensembl:ENSP00000412743|ensembl:ENSP00000414525|ensembl:ENSP00000415259	psi-mi:ykz1_yeast(display_long)|uniprotkb:YK110(orf name)|uniprotkb:YKR011C(locus name)	psi-mi:q9hcm9-2(display_long)|uniprotkb:TRIM39(gene name)|psi-mi:TRIM39(display_short)|uniprotkb:RING finger protein 23(gene name synonym)|uniprotkb:RNF23(gene name synonym)|uniprotkb:TFP(gene name synonym)|uniprotkb:Testis-abundant finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 39(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM39(gene name synonym)|uniprotkb:TIM39beta(isoform synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11544706|imex:IM-24995-2358	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000001719|refseq:NP_012936.1|mint:Q02209|dip:DIP-1923N|ensemblfungi:YKR011C(gene)|ensemblfungi:YKR011C_mRNA(transcript)|go:"GO:0005634"(nucleus)|sgd:YKR011C(identity)	intact:EBI-739510(isoform-parent)|ensembl:ENSG00000204599(gene)|ensembl:ENSG00000206495(gene)|ensembl:ENSG00000224994(gene)|ensembl:ENSG00000226437(gene)|ensembl:ENSG00000229929(gene)|ensembl:ENSG00000230308(gene)|ensembl:ENSG00000232839(gene)|ensembl:ENST00000376659(transcript)|ensembl:ENST00000383601(transcript)|ensembl:ENST00000383603(transcript)|ensembl:ENST00000396548(transcript)|ensembl:ENST00000396551(transcript)|ensembl:ENST00000400644(transcript)|ensembl:ENST00000414015(transcript)|ensembl:ENST00000419790(transcript)|ensembl:ENST00000430502(transcript)|ensembl:ENST00000431272(transcript)|ensembl:ENST00000433900(transcript)|ensembl:ENST00000438076(transcript)|ensembl:ENST00000438859(transcript)|ensembl:ENST00000440117(transcript)|ensembl:ENST00000443109(transcript)|ensembl:ENST00000446397(transcript)|ensembl:ENST00000449318(transcript)|ensembl:ENST00000450778(transcript)|ensembl:ENST00000451132(transcript)|ensembl:ENST00000452705(transcript)|ensembl:ENST00000458607(transcript)|uniprotkb:Q9HCM9-2(isoform-parent)|entrezgene/locuslink:56658(identity)	-	crc64:785423803C0EAD6A	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:DWbgg9PhX711mFipd/pvqT970D4559292	rogid:UfSn2+IVRxtGomVeDGdZpL7mz5I9606	intact-crc:9F51CBCA6FA25DB2|rigid:4pCUiK7bgdX8xPoHVTffVv/B03Q	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UGJ1-2	uniprotkb:Q01976	intact:EBI-10964469|ensembl:ENSP00000456648	intact:EBI-2344265|uniprotkb:D6VQB0|ensemblfungi:YBR111C	psi-mi:q9ugj1-2(display_long)|uniprotkb:TUBGCP4(gene name)|psi-mi:TUBGCP4(display_short)|uniprotkb:76P(gene name synonym)|uniprotkb:GCP4(gene name synonym)|uniprotkb:Gamma-ring complex protein 76 kDa(gene name synonym)	psi-mi:adpp_yeast(display_long)|uniprotkb:YSA1(gene name)|psi-mi:YSA1(display_short)|uniprotkb:ADP-ribose diphosphatase(gene name synonym)|uniprotkb:Adenosine diphosphoribose pyrophosphatase(gene name synonym)|uniprotkb:ADP-ribose phosphohydrolase(gene name synonym)|uniprotkb:YBR0907(orf name)|uniprotkb:YBR111C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11544697|imex:IM-24995-2357	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-1052544(isoform-parent)|ensembl:ENSG00000137822(gene)|ensembl:ENST00000564079(transcript)|uniprotkb:Q9UGJ1-2(isoform-parent)|entrezgene/locuslink:27229(identity)	refseq:NP_009669.1|sgd:S000000315|interpro:IPR020084|interpro:IPR000086(NUDIX hydrolase, core)|interpro:IPR015797(NUDIX)|reactome:R-SCE-2393930|ensemblfungi:YBR111C(gene)|ensemblfungi:YBR111C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006753"(nucleoside phosphate metabolic process)|go:"GO:0019693"(ribose phosphate metabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0047631"(ADP-ribose diphosphatase activity)|sgd:YBR111C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:+lfeIRS3N2OU1+y84kUyKY7ePNA9606	rogid:tpdVT9ttt/pL+UevSr0zW+rfyIc559292	intact-crc:4B9E186E62315C8D|rigid:Nl6vjWQsboG3a+WfLlabYcKtJaI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9H8Y8	uniprotkb:Q01976	intact:EBI-739467|uniprotkb:Q96I74|uniprotkb:Q96K84|uniprotkb:Q9H946|uniprotkb:Q9UFW4|uniprotkb:Q53TE3|intact:EBI-28970723|uniprotkb:B4DKT0|ensembl:ENSP00000234160	intact:EBI-2344265|uniprotkb:D6VQB0|ensemblfungi:YBR111C	psi-mi:gors2_human(display_long)|uniprotkb:GORASP2(gene name)|psi-mi:GORASP2(display_short)|uniprotkb:Golgi reassembly-stacking protein of 55 kDa(gene name synonym)|uniprotkb:p59(gene name synonym)|uniprotkb:Golgi phosphoprotein 6(gene name synonym)|uniprotkb:GOLPH6(gene name synonym)	psi-mi:adpp_yeast(display_long)|uniprotkb:YSA1(gene name)|psi-mi:YSA1(display_short)|uniprotkb:ADP-ribose diphosphatase(gene name synonym)|uniprotkb:Adenosine diphosphoribose pyrophosphatase(gene name synonym)|uniprotkb:ADP-ribose phosphohydrolase(gene name synonym)|uniprotkb:YBR0907(orf name)|uniprotkb:YBR111C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11544688|imex:IM-24995-2356	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000234160|refseq:NP_001188357.1|refseq:NP_056345.3|refseq:XP_006712471.1|ensembl:ENSG00000115806(gene)|ensembl:ENST00000234160(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006996"(organelle organization)|go:"GO:0007030"(Golgi organization)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016020"(membrane)|go:"GO:0030154"(cell differentiation)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0061951"(establishment of protein localization to plasma membrane)|go:"GO:0070925"(organelle assembly)|interpro:IPR007583(GRASP55/65)|interpro:IPR024958|interpro:IPR036034|mint:Q9H8Y8|rcsb pdb:3RLE|rcsb pdb:4EDJ|reactome:R-HSA-162658|entrezgene/locuslink:26003(identity)	refseq:NP_009669.1|sgd:S000000315|interpro:IPR020084|interpro:IPR000086(NUDIX hydrolase, core)|interpro:IPR015797(NUDIX)|reactome:R-SCE-2393930|ensemblfungi:YBR111C(gene)|ensemblfungi:YBR111C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006753"(nucleoside phosphate metabolic process)|go:"GO:0019693"(ribose phosphate metabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0047631"(ADP-ribose diphosphatase activity)|sgd:YBR111C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:xSy3HsObmteg/doer5eLoZiz+fU9606	rogid:tpdVT9ttt/pL+UevSr0zW+rfyIc559292	intact-crc:5C6358B7BBABC3B8|rigid:OHa3n2x9t+6nqKgGZYVRAB//z5Q	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q01976	uniprotkb:Q13490	intact:EBI-2344265|uniprotkb:D6VQB0|ensemblfungi:YBR111C	intact:EBI-514538|uniprotkb:Q16516|uniprotkb:Q4TTG0|uniprotkb:B4E026|ensembl:ENSP00000227758|ensembl:ENSP00000477613	psi-mi:adpp_yeast(display_long)|uniprotkb:YSA1(gene name)|psi-mi:YSA1(display_short)|uniprotkb:ADP-ribose diphosphatase(gene name synonym)|uniprotkb:Adenosine diphosphoribose pyrophosphatase(gene name synonym)|uniprotkb:ADP-ribose phosphohydrolase(gene name synonym)|uniprotkb:YBR0907(orf name)|uniprotkb:YBR111C(locus name)	psi-mi:birc2_human(display_long)|uniprotkb:Inhibitor of apoptosis protein 2(gene name synonym)|uniprotkb:TNFR2-TRAF-signaling complex protein 2(gene name synonym)|uniprotkb:IAP homolog B(gene name synonym)|uniprotkb:RING finger protein 48(gene name synonym)|uniprotkb:BIRC2(gene name)|psi-mi:BIRC2(display_short)|uniprotkb:API1(gene name synonym)|uniprotkb:MIHB(gene name synonym)|uniprotkb:RNF48(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase BIRC2(gene name synonym)|uniprotkb:Cellular inhibitor of apoptosis 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11544679|imex:IM-24995-2355	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009669.1|sgd:S000000315|interpro:IPR020084|interpro:IPR000086(NUDIX hydrolase, core)|interpro:IPR015797(NUDIX)|reactome:R-SCE-2393930|ensemblfungi:YBR111C(gene)|ensemblfungi:YBR111C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006753"(nucleoside phosphate metabolic process)|go:"GO:0019693"(ribose phosphate metabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0047631"(ADP-ribose diphosphatase activity)|sgd:YBR111C(identity)	refseq:NP_001157.1|refseq:NP_001243095.1|refseq:NP_001243092.1|dip:DIP-33485N|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0045471"(response to ethanol)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051087"(chaperone binding)|go:"GO:0051591"(response to cAMP)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060544"(regulation of necroptotic process)|go:"GO:0060546"(negative regulation of necroptotic process)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070266"(necroptotic process)|go:"GO:0070424"(regulation of nucleotide-binding oligomerization domain containing signaling pathway)|go:"GO:0098770"(FBXO family protein binding)|go:"GO:1901222"(regulation of NIK/NF-kappaB signaling)|go:"GO:1902443"(negative regulation of ripoptosome assembly involved in necroptotic process)|go:"GO:1902523"(positive regulation of protein K63-linked ubiquitination)|go:"GO:1902524"(positive regulation of protein K48-linked ubiquitination)|go:"GO:1902527"(positive regulation of protein monoubiquitination)|go:"GO:2000116"(regulation of cysteine-type endopeptidase activity)|go:"GO:2000377"(regulation of reactive oxygen species metabolic process)|interpro:IPR001315(Caspase Recruitment)|interpro:IPR001370(Proteinase inhibitor I32, inhibitor of apoptosis)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011029(DEATH-like)|interpro:IPR041933|mint:Q13490|rcsb pdb:1QBH|rcsb pdb:2L9M|rcsb pdb:3D9T|rcsb pdb:3D9U|rcsb pdb:3M1D|rcsb pdb:3MUP|rcsb pdb:3OZ1|rcsb pdb:3T6P|rcsb pdb:3UW4|rcsb pdb:4EB9|rcsb pdb:4HY4|rcsb pdb:4HY5|rcsb pdb:4KMN|rcsb pdb:4LGE|rcsb pdb:4LGU|rcsb pdb:4MTI|rcsb pdb:4MU7|rcsb pdb:5M6N|rcsb pdb:6EXW|rcsb pdb:6HPR|rcsb pdb:6W74|rcsb pdb:6W7O|rcsb pdb:6W8I|reactome:R-HSA-111465|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-5213460|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5668541|reactome:R-HSA-5675482|reactome:R-HSA-5676594|reactome:R-HSA-5689880|reactome:R-HSA-937041|ensembl:ENSG00000110330(gene)|ensembl:ENST00000227758(transcript)|ensembl:ENST00000613397(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001741"(XY body)|go:"GO:0001890"(placenta development)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0016740"(transferase activity)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034121"(regulation of toll-like receptor signaling pathway)|go:"GO:0035631"(CD40 receptor complex)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0039535"(regulation of RIG-I signaling pathway)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|entrezgene/locuslink:329(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:tpdVT9ttt/pL+UevSr0zW+rfyIc559292	rogid:FOikzyDyDtlv2l69i/WNDNq674A9606	intact-crc:C9DE53BF2D7E8937|rigid:vhDiILxBzyjxGTbwEavei/yZJ00	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P98170	uniprotkb:Q01976	intact:EBI-517127|uniprotkb:Q9NQ14|uniprotkb:D3DTF2|ensembl:ENSP00000347858|ensembl:ENSP00000360242|ensembl:ENSP00000395230	intact:EBI-2344265|uniprotkb:D6VQB0|ensemblfungi:YBR111C	psi-mi:xiap_human(display_long)|uniprotkb:Inhibitor of apoptosis protein 3(gene name synonym)|uniprotkb:X-linked inhibitor of apoptosis protein(gene name synonym)|uniprotkb:IAP-like protein(gene name synonym)|uniprotkb:XIAP(gene name)|psi-mi:XIAP(display_short)|uniprotkb:API3(gene name synonym)|uniprotkb:IAP3(gene name synonym)|uniprotkb:BIRC4(gene name synonym)|uniprotkb:Baculoviral IAP repeat-containing protein 4(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase XIAP(gene name synonym)	psi-mi:adpp_yeast(display_long)|uniprotkb:YSA1(gene name)|psi-mi:YSA1(display_short)|uniprotkb:ADP-ribose diphosphatase(gene name synonym)|uniprotkb:Adenosine diphosphoribose pyrophosphatase(gene name synonym)|uniprotkb:ADP-ribose phosphohydrolase(gene name synonym)|uniprotkb:YBR0907(orf name)|uniprotkb:YBR111C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11544670|imex:IM-24995-2354	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006724817.1|refseq:NP_001158.2|refseq:NP_001191330.1|refseq:XP_011529631.1|dip:DIP-27626N|ensembl:ENSG00000101966(gene)|ensembl:ENST00000355640(transcript)|ensembl:ENST00000371199(transcript)|ensembl:ENST00000434753(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005876"(spindle microtubule)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030510"(regulation of BMP signaling pathway)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0055070"(copper ion homeostasis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070424"(regulation of nucleotide-binding oligomerization domain containing signaling pathway)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:1902530"(positive regulation of protein linear polyubiquitination)|go:"GO:1990001"(inhibition of cysteine-type endopeptidase activity involved in apoptotic process)|interpro:IPR001370(Proteinase inhibitor I32, inhibitor of apoptosis)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011029(DEATH-like)|interpro:IPR042579|mint:P98170|rcsb pdb:1C9Q|rcsb pdb:1F9X|rcsb pdb:1G3F|rcsb pdb:1G73|rcsb pdb:1I3O|rcsb pdb:1I4O|rcsb pdb:1I51|rcsb pdb:1KMC|rcsb pdb:1NW9|rcsb pdb:1TFQ|rcsb pdb:1TFT|rcsb pdb:2ECG|rcsb pdb:2JK7|rcsb pdb:2KNA|rcsb pdb:2OPY|rcsb pdb:2OPZ|rcsb pdb:2POI|rcsb pdb:2POP|rcsb pdb:2QRA|rcsb pdb:2VSL|rcsb pdb:3CLX|rcsb pdb:3CM2|rcsb pdb:3CM7|rcsb pdb:3EYL|rcsb pdb:3G76|rcsb pdb:3HL5|rcsb pdb:3UW4|rcsb pdb:3UW5|rcsb pdb:4EC4|rcsb pdb:4HY0|rcsb pdb:4IC2|rcsb pdb:4IC3|rcsb pdb:4J3Y|rcsb pdb:4J44|rcsb pdb:4J45|rcsb pdb:4J46|rcsb pdb:4J47|rcsb pdb:4J48|rcsb pdb:4KJU|rcsb pdb:4KJV|rcsb pdb:4KMP|rcsb pdb:4MTZ|rcsb pdb:4OXC|rcsb pdb:4WVS|rcsb pdb:4WVT|rcsb pdb:4WVU|rcsb pdb:5C0K|rcsb pdb:5C0L|rcsb pdb:5C3H|rcsb pdb:5C3K|rcsb pdb:5C7A|rcsb pdb:5C7B|rcsb pdb:5C7C|rcsb pdb:5C7D|rcsb pdb:5C83|rcsb pdb:5C84|rcsb pdb:5M6E|rcsb pdb:5M6F|rcsb pdb:5M6H|rcsb pdb:5M6L|rcsb pdb:5M6M|rcsb pdb:5O6T|rcsb pdb:5OQW|rcsb pdb:6EY2|rcsb pdb:6GJW|rcsb pdb:6QCI|reactome:R-HSA-111459|reactome:R-HSA-111463|reactome:R-HSA-111464|reactome:R-HSA-111469|reactome:R-HSA-3769402|reactome:R-HSA-5213460|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5675482|reactome:R-HSA-8948747|reactome:R-HSA-8948751|reactome:R-HSA-9627069|entrezgene/locuslink:331(identity)	refseq:NP_009669.1|sgd:S000000315|interpro:IPR020084|interpro:IPR000086(NUDIX hydrolase, core)|interpro:IPR015797(NUDIX)|reactome:R-SCE-2393930|ensemblfungi:YBR111C(gene)|ensemblfungi:YBR111C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006753"(nucleoside phosphate metabolic process)|go:"GO:0019693"(ribose phosphate metabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0047631"(ADP-ribose diphosphatase activity)|sgd:YBR111C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:6eDcOay+c2ZmIAD/pwnCDROBwgM9606	rogid:tpdVT9ttt/pL+UevSr0zW+rfyIc559292	intact-crc:7EF69C5681307E9C|rigid:G4yBzu9FXOxAZj65iK+olxZAd+g	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O96015	uniprotkb:Q02647	intact:EBI-742362|uniprotkb:Q6FGB2|uniprotkb:Q6FGD0|ensembl:ENSP00000216068	intact:EBI-6240|uniprotkb:D6VT54|ensemblfungi:YDR424C	psi-mi:dnal4_human(display_long)|uniprotkb:DNAL4(gene name)|psi-mi:DNAL4(display_short)	psi-mi:dyl1_yeast(display_long)|uniprotkb:DYN2(gene name)|psi-mi:DYN2(display_short)|uniprotkb:SLC1(gene name synonym)|uniprotkb:YDR424C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11544743|imex:IM-24995-2362	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005731.1|ensembl:ENSG00000100246(gene)|ensembl:ENST00000216068(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0030286"(dynein complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0051959"(dynein light intermediate chain binding)|go:"GO:2000582"(obsolete positive regulation of microtubule motor activity, plus-end-directed)|interpro:IPR001372(Dynein light chain, type 1 and 2)|interpro:IPR037177|mint:O96015|reactome:R-HSA-177504|go:"GO:0003777"(microtubule motor activity)|entrezgene/locuslink:10126(identity)	refseq:NP_010712.1|sgd:S000002832|dip:DIP-6480N|mint:Q02647|interpro:IPR001372(Dynein light chain, type 1 and 2)|interpro:IPR019763|interpro:IPR037177|rcsb pdb:4DS1|rcsb pdb:4HT6|reactome:R-SCE-6798695|ensemblfungi:YDR424C(gene)|ensemblfungi:YDR424C_mRNA(transcript)|go:"GO:0005643"(nuclear pore)|go:"GO:0005868"(cytoplasmic dynein complex)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0015031"(protein transport)|go:"GO:0030286"(dynein complex)|go:"GO:0030473"(nuclear migration along microtubule)|go:"GO:0034399"(nuclear periphery)|go:"GO:0040001"(establishment of mitotic spindle localization)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0051028"(mRNA transport)|go:"GO:0051292"(nuclear pore complex assembly)|go:"GO:0051959"(dynein light intermediate chain binding)|go:"GO:1990429"(peroxisomal importomer complex)|go:"GO:2000582"(obsolete positive regulation of microtubule motor activity, plus-end-directed)|sgd:YDR424C(identity)	-	-	crc64:C25A690F35C3CEEC	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:VT8OXlxBh2Jy6Bb4vMkrAY9M6AA9606	rogid:VzzUwItKMyp/zI7n/iI7VK4QiEA559292	intact-crc:4F9CADD181A2304B|rigid:eccgkpyu1hz19GLGuUcA3KLr8xU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P55347	uniprotkb:Q02642	intact:EBI-1373569|uniprotkb:O00528|uniprotkb:Q8IWT7|ensembl:ENSP00000291547	intact:EBI-6371|uniprotkb:Q02107|uniprotkb:D6W3X7|ensemblfungi:YPL037C	psi-mi:pknx1_human(display_long)|uniprotkb:PBX/knotted homeobox 1(gene name synonym)|uniprotkb:Homeobox protein PREP-1(gene name synonym)|uniprotkb:PKNOX1(gene name)|psi-mi:PKNOX1(display_short)|uniprotkb:PREP1(gene name synonym)	psi-mi:nacb1_yeast(display_long)|uniprotkb:EGD1(gene name)|psi-mi:EGD1(display_short)|uniprotkb:Beta-1-NAC(gene name synonym)|uniprotkb:GAL4 DNA-binding enhancer protein 1(gene name synonym)|uniprotkb:BTF3 homolog EGD1(gene name synonym)|uniprotkb:YPL037C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11544734|imex:IM-24995-2361	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004562.2|ensembl:ENSG00000160199(gene)|ensembl:ENST00000291547(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0030217"(T cell differentiation)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0043010"(camera-type eye development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR008422(Coprinus cinereus mating-type protein)|interpro:IPR009057(Homeodomain-like)|interpro:IPR032453|rcsb pdb:1X2N|reactome:R-HSA-5617472|entrezgene/locuslink:5316(identity)	refseq:NP_015288.1|sgd:S000005958|mint:Q02642|dip:DIP-6561N|ensemblfungi:YPL037C(gene)|ensemblfungi:YPL037C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005854"(nascent polypeptide-associated complex)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR002715(Nascent polypeptide-associated complex NAC)|interpro:IPR038187|interpro:IPR039370|sgd:YPL037C(identity)	-	-	crc64:7C278A3DC79BF95B	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Lg1nUBFHfBFWvGVk9elIXobm5BA9606	rogid:Lrun0emRynb8tO3ViEF/fkUI9SQ559292	intact-crc:8710BF078E78278F|rigid:bfalhloM1t44nFIvMTfX3o8/9XE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q02642	uniprotkb:P50222	intact:EBI-6371|uniprotkb:Q02107|uniprotkb:D6W3X7|ensemblfungi:YPL037C	intact:EBI-748397|uniprotkb:O75263|ensembl:ENSP00000262041|uniprotkb:Q9UPL6|uniprotkb:B2R8I7|intact:EBI-10172134|intact:EBI-11522964|intact:EBI-11750003|intact:EBI-12702266|uniprotkb:A4D127	psi-mi:nacb1_yeast(display_long)|uniprotkb:EGD1(gene name)|psi-mi:EGD1(display_short)|uniprotkb:Beta-1-NAC(gene name synonym)|uniprotkb:GAL4 DNA-binding enhancer protein 1(gene name synonym)|uniprotkb:BTF3 homolog EGD1(gene name synonym)|uniprotkb:YPL037C(locus name)	psi-mi:meox2_human(display_long)|uniprotkb:Mesenchyme homeobox 2(gene name synonym)|uniprotkb:Growth arrest-specific homeobox(gene name synonym)|uniprotkb:MEOX2(gene name)|psi-mi:MEOX2(display_short)|uniprotkb:GAX(gene name synonym)|uniprotkb:MOX2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11544725|imex:IM-24995-2360	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015288.1|sgd:S000005958|mint:Q02642|dip:DIP-6561N|ensemblfungi:YPL037C(gene)|ensemblfungi:YPL037C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005854"(nascent polypeptide-associated complex)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR002715(Nascent polypeptide-associated complex NAC)|interpro:IPR038187|interpro:IPR039370|sgd:YPL037C(identity)	ensembl:ENSG00000106511(gene)|ensembl:ENST00000262041(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0001757"(somite specification)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007275"(multicellular organism development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008015"(blood circulation)|go:"GO:0016607"(nuclear speck)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060173"(limb development)|go:"GO:0061053"(somite development)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR042634|refseq:NP_005915.2|entrezgene/locuslink:4223(identity)	-	crc64:7C278A3DC79BF95B	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2017/05/26	rogid:Lrun0emRynb8tO3ViEF/fkUI9SQ559292	rogid:fMv0ruKikzQ3MC0PBvJ3pOAjW+U9606	intact-crc:CDD8E36AD7F1A087|rigid:n/w0hlOZmoo3PjnN4OQurGwqP9o	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9Y5P8-2	uniprotkb:Q02256	intact:EBI-11534240	intact:EBI-14322|uniprotkb:D6VVV7|ensemblfungi:YIR026C	psi-mi:q9y5p8-2(display_long)|uniprotkb:PP2A subunit B isoform PR48(gene name synonym)|uniprotkb:PPP2R3L(gene name synonym)|uniprotkb:Protein phosphatase 2A 48 kDa regulatory subunit(gene name synonym)|uniprotkb:PPP2R3B(gene name)|psi-mi:PPP2R3B(display_short)	psi-mi:pvh1_yeast(display_long)|uniprotkb:YIR026C(locus name)|uniprotkb:YVH1(gene name)|psi-mi:YVH1(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11544716|imex:IM-24995-2359	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-2479826(isoform-parent)|entrezgene/locuslink:28227(identity)	ensemblfungi:YIR026C_mRNA(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|ensemblfungi:YIR026C(gene)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0008138"(protein tyrosine/serine/threonine phosphatase activity)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0030476"(ascospore wall assembly)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:1990275"(preribosome binding)|go:"GO:2000786"(positive regulation of autophagosome assembly)|interpro:IPR000340(Protein-tyrosine phosphatase, dual specificity)|interpro:IPR000387(Protein-tyrosine phosphatase)|sgd:S000001465|interpro:IPR020422|interpro:IPR029021|rcsb pdb:6N8M|interpro:IPR016278(Tyrosine protein phosphatase, dual specificity, 12)|rcsb pdb:6N8N|rcsb pdb:6N8O|rcsb pdb:6RZZ|rcsb pdb:6S05|refseq:NP_012292.3|mint:Q02256|dip:DIP-5192N|sgd:YIR026C(identity)	-	-	crc64:9E75C7CC14353B43	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:u/vhz15um2LQ5BCN/pXjf+NVCTc9606	rogid:9C9+S3aubsVjSLE5Kklpws+PA0A559292	intact-crc:35536F24328AE060|rigid:VWGXq5x4MxFS/EKpecUkXmORX84	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8N6L0	uniprotkb:Q02724	intact:EBI-749265|uniprotkb:Q96MC3|ensembl:ENSP00000404220	intact:EBI-20050|uniprotkb:D6W3Z2|ensemblfungi:YPL020C	psi-mi:kash5_human(display_long)|uniprotkb:KASH5(gene name)|psi-mi:KASH5(display_short)|uniprotkb:CCDC155(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 155(gene name synonym)|uniprotkb:KASH domain-containing protein 5(gene name synonym)	psi-mi:ulp1_yeast(display_long)|uniprotkb:ULP1(gene name)|psi-mi:ULP1(display_short)|uniprotkb:LPB11C(orf name)|uniprotkb:YPL020C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11544781|imex:IM-24995-2366	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_653289.3|ensembl:ENSG00000161609(gene)|ensembl:ENST00000447857(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034397"(telomere localization)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051225"(spindle assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0090172"(microtubule cytoskeleton organization involved in homologous chromosome segregation)|go:"GO:0090220"(chromosome localization to nuclear envelope involved in homologous chromosome segregation)|go:"GO:0090619"(meiotic spindle pole)|interpro:IPR011992(EF-Hand type)|interpro:IPR028168|interpro:IPR028170|interpro:IPR039508|mint:Q8N6L0|rcsb pdb:6R2I|rcsb pdb:6WMF|entrezgene/locuslink:147872(identity)	refseq:NP_015305.1|sgd:S000005941|ensemblfungi:YPL020C(gene)|ensemblfungi:YPL020C_mRNA(transcript)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005730"(nucleolus)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0016926"(protein desumoylation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070140"(SUMO-specific isopeptidase activity)|interpro:IPR003653(Peptidase C48, SUMO/Sentrin/Ubl1)|interpro:IPR038765|rcsb pdb:1EUV|rcsb pdb:2HKP|rcsb pdb:2HL8|rcsb pdb:2HL9|rcsb pdb:5H2V|rcsb pdb:5H2W|rcsb pdb:5H2X|reactome:R-SCE-3065679|reactome:R-SCE-6791226|dip:DIP-4041N|mint:Q02724|sgd:YPL020C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Wl9L7AcvDHCZuKjYLn8QgGIbZTc9606	rogid:H9B4qZf/ZMbHr7u4hbtR4fzz0ec559292	intact-crc:005911C666FE926F|rigid:kcJcZoruEPpVCr09h4BbpwgBs2s	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q02724	uniprotkb:Q6RW13-2	intact:EBI-20050|uniprotkb:D6W3Z2|ensemblfungi:YPL020C	intact:EBI-11522760|ensembl:ENSP00000365816	psi-mi:ulp1_yeast(display_long)|uniprotkb:ULP1(gene name)|psi-mi:ULP1(display_short)|uniprotkb:LPB11C(orf name)|uniprotkb:YPL020C(locus name)	psi-mi:q6rw13-2(display_long)|uniprotkb:AGTRAP(gene name)|psi-mi:AGTRAP(display_short)|uniprotkb:AT1 receptor-associated protein(gene name synonym)|uniprotkb:ATRAP(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11544772|imex:IM-24995-2365	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015305.1|sgd:S000005941|ensemblfungi:YPL020C(gene)|ensemblfungi:YPL020C_mRNA(transcript)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005730"(nucleolus)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0016926"(protein desumoylation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070140"(SUMO-specific isopeptidase activity)|interpro:IPR003653(Peptidase C48, SUMO/Sentrin/Ubl1)|interpro:IPR038765|rcsb pdb:1EUV|rcsb pdb:2HKP|rcsb pdb:2HL8|rcsb pdb:2HL9|rcsb pdb:5H2V|rcsb pdb:5H2W|rcsb pdb:5H2X|reactome:R-SCE-3065679|reactome:R-SCE-6791226|dip:DIP-4041N|mint:Q02724|sgd:YPL020C(identity)	ensembl:ENSG00000177674(gene)|ensembl:ENST00000376629(transcript)|intact:EBI-741181(isoform-parent)|uniprotkb:Q6RW13-2(isoform-parent)|entrezgene/locuslink:57085(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:H9B4qZf/ZMbHr7u4hbtR4fzz0ec559292	rogid:PNzVis/8puQZBJ562gCqZKc078s9606	intact-crc:4D8EC003013CB6EF|rigid:71n37RR9MkaYxPdD0E2912OYv14	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q15041	uniprotkb:Q02724	intact:EBI-714543|ensembl:ENSP00000306788|uniprotkb:B7Z6S5|uniprotkb:B7Z791|uniprotkb:F5GXP4	intact:EBI-20050|uniprotkb:D6W3Z2|ensemblfungi:YPL020C	psi-mi:ar6p1_human(display_long)|uniprotkb:ARL6IP(gene name synonym)|uniprotkb:ARL6IP1(gene name)|psi-mi:ARL6IP1(display_short)|uniprotkb:KIAA0069(gene name synonym)|uniprotkb:ARMER(gene name synonym)|uniprotkb:Apoptotic regulator in the membrane of the endoplasmic reticulum(gene name synonym)	psi-mi:ulp1_yeast(display_long)|uniprotkb:ULP1(gene name)|psi-mi:ULP1(display_short)|uniprotkb:LPB11C(orf name)|uniprotkb:YPL020C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11544763|imex:IM-24995-2364	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055976.1|ensembl:ENSG00000170540(gene)|ensembl:ENST00000304414(transcript)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006613"(cotranslational protein targeting to membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0071787"(endoplasmic reticulum tubular network formation)|go:"GO:1903371"(regulation of endoplasmic reticulum tubular network organization)|go:"GO:1990809"(endoplasmic reticulum tubular network membrane organization)|interpro:IPR033301|mint:Q15041|go:"GO:0002038"(positive regulation of L-glutamate import across plasma membrane)|refseq:NP_001300787.1|entrezgene/locuslink:23204(identity)	refseq:NP_015305.1|sgd:S000005941|ensemblfungi:YPL020C(gene)|ensemblfungi:YPL020C_mRNA(transcript)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005730"(nucleolus)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0016926"(protein desumoylation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070140"(SUMO-specific isopeptidase activity)|interpro:IPR003653(Peptidase C48, SUMO/Sentrin/Ubl1)|interpro:IPR038765|rcsb pdb:1EUV|rcsb pdb:2HKP|rcsb pdb:2HL8|rcsb pdb:2HL9|rcsb pdb:5H2V|rcsb pdb:5H2W|rcsb pdb:5H2X|reactome:R-SCE-3065679|reactome:R-SCE-6791226|dip:DIP-4041N|mint:Q02724|sgd:YPL020C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:3fjkoyvUx25po7xsPcXgpjEeLJg9606	rogid:H9B4qZf/ZMbHr7u4hbtR4fzz0ec559292	intact-crc:9961DE71A2AC89D1|rigid:RIbaQ21M7h0vj230QEBaFTZm9ok	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8IYA8	uniprotkb:Q02647	intact:EBI-8638439|intact:EBI-28969497|ensembl:ENSP00000296449|ensembl:ENSP00000391788|ensembl:ENSP00000407837|uniprotkb:C9JJL0|uniprotkb:Q96LP7|intact:MINT-8162095|uniprotkb:Q05DG9	intact:EBI-6240|uniprotkb:D6VT54|ensemblfungi:YDR424C	psi-mi:iho1_human(display_long)|uniprotkb:IHO1(gene name)|psi-mi:IHO1(display_short)|uniprotkb:CCDC36(gene name synonym)|uniprotkb:Cancer/testis antigen 74(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 36(gene name synonym)	psi-mi:dyl1_yeast(display_long)|uniprotkb:DYN2(gene name)|psi-mi:DYN2(display_short)|uniprotkb:SLC1(gene name synonym)|uniprotkb:YDR424C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11544752|imex:IM-24995-2363	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000296449|ensembl:ENST00000366429|ensembl:ENSP00000403700|ensembl:ENSP00000391788|ensembl:ENSP00000407837|ensembl:ENSG00000173421(gene)|ensembl:ENST00000296449(transcript)|ensembl:ENST00000438782(transcript)|ensembl:ENST00000452691(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0006310"(DNA recombination)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0042138"(meiotic DNA double-strand break formation)|go:"GO:0048477"(oogenesis)|go:"GO:0060629"(regulation of homologous chromosome segregation)|interpro:IPR031529|mint:Q8IYA8|refseq:XP_011531974.1|refseq:XP_011531975.1|refseq:NP_001128669.1|refseq:NP_835467.2|refseq:XP_006713187.1|entrezgene/locuslink:339834(identity)	refseq:NP_010712.1|sgd:S000002832|dip:DIP-6480N|mint:Q02647|interpro:IPR001372(Dynein light chain, type 1 and 2)|interpro:IPR019763|interpro:IPR037177|rcsb pdb:4DS1|rcsb pdb:4HT6|reactome:R-SCE-6798695|ensemblfungi:YDR424C(gene)|ensemblfungi:YDR424C_mRNA(transcript)|go:"GO:0005643"(nuclear pore)|go:"GO:0005868"(cytoplasmic dynein complex)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0015031"(protein transport)|go:"GO:0030286"(dynein complex)|go:"GO:0030473"(nuclear migration along microtubule)|go:"GO:0034399"(nuclear periphery)|go:"GO:0040001"(establishment of mitotic spindle localization)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0051028"(mRNA transport)|go:"GO:0051292"(nuclear pore complex assembly)|go:"GO:0051959"(dynein light intermediate chain binding)|go:"GO:1990429"(peroxisomal importomer complex)|go:"GO:2000582"(obsolete positive regulation of microtubule motor activity, plus-end-directed)|sgd:YDR424C(identity)	-	comment:mint	crc64:C25A690F35C3CEEC	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:+TNQLExkhmC1NWqsE240Cx7zFVU9606	rogid:VzzUwItKMyp/zI7n/iI7VK4QiEA559292	intact-crc:96EC21020C3B738C|rigid:gohT56T3Co0JinL5kHIziH3vKxc	false	sufficient binding region:11-594	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O00444	uniprotkb:Q02793	intact:EBI-746202|uniprotkb:Q8IYF0|uniprotkb:Q96Q95|uniprotkb:B2RAL0|uniprotkb:B7Z837|uniprotkb:B7Z8G7|uniprotkb:Q9UD84|uniprotkb:Q9UDE2|ensembl:ENSP00000270861	intact:EBI-17260|uniprotkb:D6VTU2|ensemblfungi:YGL213C	psi-mi:plk4_human(display_long)|uniprotkb:Polo-like kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase Sak(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 18(gene name synonym)|uniprotkb:PLK4(gene name)|psi-mi:PLK4(display_short)|uniprotkb:SAK(gene name synonym)|uniprotkb:STK18(gene name synonym)	psi-mi:ski8_yeast(display_long)|uniprotkb:YGL213C(locus name)|uniprotkb:SKI8(gene name)|psi-mi:SKI8(display_short)|uniprotkb:REC103(gene name synonym)|uniprotkb:Superkiller protein 8(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11544826|imex:IM-24995-2371	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001177728.1|refseq:NP_001177730.1|refseq:NP_055079.3|dip:DIP-34467N|rcsb pdb:5LHZ|rcsb pdb:6N45|rcsb pdb:6N46|rcsb pdb:6W38|rcsb pdb:6W3I|rcsb pdb:6W3J|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|rcsb pdb:5LHY|reactome:R-HSA-5620912|reactome:R-HSA-8854518|ensembl:ENSG00000142731(gene)|ensembl:ENST00000270861(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0001741"(XY body)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007099"(centriole replication)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0046601"(positive regulation of centriole replication)|go:"GO:0060271"(cilium assembly)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0098535"(de novo centriole assembly involved in multi-ciliated epithelial cell differentiation)|go:"GO:0098536"(deuterosome)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033696|interpro:IPR033698|interpro:IPR033699|interpro:IPR033700|mint:O00444|rcsb pdb:2N19|rcsb pdb:3COK|rcsb pdb:4JXF|rcsb pdb:4N7V|rcsb pdb:4N7Z|rcsb pdb:4N9J|rcsb pdb:4YUR|rcsb pdb:4YYP|entrezgene/locuslink:10733(identity)	refseq:NP_011302.1|sgd:S000003181|ensemblfungi:YGL213C(gene)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034622"|go:"GO:0051607"(defense response to virus)|go:"GO:0055087"(Ski complex)|go:"GO:0065004"(protein-DNA complex assembly)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|rcsb pdb:1S4U|rcsb pdb:1SQ9|rcsb pdb:4BUJ|rcsb pdb:5MC6|reactome:R-SCE-429958|reactome:R-SCE-674695|reactome:R-SCE-75955|ensemblfungi:YGL213C_mRNA(transcript)|dip:DIP-1653N|mint:Q02793|sgd:YGL213C(identity)	-	-	crc64:C5E7B9D2268F9727	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:xqjVEnoGXDk/+2AzLRAkyPK80OI9606	rogid:6K6FJYcctdlT1321Nv6pOnQPwq8559292	intact-crc:E1A47DD0F281A306|rigid:b94IcmKAtMw/tw+81P5wYoO+MTk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96BA8	uniprotkb:Q02774	intact:EBI-6942903|ensembl:ENSP00000481956|intact:MINT-268046|intact:MINT-8162577|uniprotkb:Q8N2D5|uniprotkb:Q96CP0	intact:EBI-17099|uniprotkb:Q12413|ensemblfungi:YDL212W|uniprotkb:D6VRE2	psi-mi:cr3l1_human(display_long)|uniprotkb:CREB3L1(gene name)|psi-mi:CREB3L1(display_short)|uniprotkb:OASIS(gene name synonym)|uniprotkb:PSEC0238(orf name)|uniprotkb:Old astrocyte specifically-induced substance(gene name synonym)	psi-mi:shr3_yeast(display_long)|uniprotkb:D1022(orf name)|uniprotkb:YDL212W(locus name)|uniprotkb:SHR3(gene name)|psi-mi:SHR3(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11544817|imex:IM-24995-2370	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157613(gene)|ensembl:ENST00000621158(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0070278"(extracellular matrix constituent secretion)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029805|mint:Q96BA8|reactome:R-HSA-8874211|refseq:NP_443086.1|entrezgene/locuslink:90993(identity)	refseq:NP_010069.1|sgd:S000002371|ensemblfungi:YDL212W(gene)|ensemblfungi:YDL212W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006457"(protein folding)|go:"GO:0006865"(amino acid transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0015031"(protein transport)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0043332"(mating projection tip)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0090114"(COPII-coated vesicle budding)|interpro:IPR013248(Shr3 amino acid permease chaperone)|dip:DIP-1615N|mint:Q02774|sgd:YDL212W(identity)	-	comment:mint|function:"Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE"	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:sMWUFmBeBBCO+T0Y2CuB/un1lBg9606	rogid:IGYbkr6cAVoYYx9LhZxB/B9Onnc559292	intact-crc:E339E3B9AA1F3F1E|rigid:UDV0bPWPNi4/8lKzGW+XAxfEZNg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q02771	uniprotkb:Q9UMX0	intact:EBI-14092|ensemblfungi:YER058W|uniprotkb:D3DLW2	intact:EBI-741480|uniprotkb:Q8IXS9|uniprotkb:Q8N2Q3|uniprotkb:Q9H0T8|uniprotkb:Q9H3R4|uniprotkb:Q9HAZ5|intact:EBI-28967608|ensembl:ENSP00000365576|uniprotkb:Q5T6J5|uniprotkb:Q5T6J9|uniprotkb:A0A024R284	psi-mi:pt117_yeast(display_long)|uniprotkb:PET117(gene name)|psi-mi:PET117(display_short)|uniprotkb:YER058W(locus name)	psi-mi:ubql1_human(display_long)|uniprotkb:Protein linking IAP with cytoskeleton 1(gene name synonym)|uniprotkb:UBQLN1(gene name)|psi-mi:UBQLN1(display_short)|uniprotkb:DA41(gene name synonym)|uniprotkb:PLIC1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11544808|imex:IM-24995-2369	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000000860|refseq:NP_010979.1|ensemblfungi:YER058W(gene)|ensemblfungi:YER058W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0033617"(mitochondrial cytochrome c oxidase assembly)|go:"GO:0099616"(extrinsic component of matrix side of mitochondrial inner membrane)|interpro:IPR031568|dip:DIP-5118N|sgd:YER058W(identity)	ensembl:ENST00000257468|ensembl:ENSP00000257468|ensembl:ENSP00000365576|ensembl:ENSG00000135018(gene)|ensembl:ENST00000376395(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000502"(proteasome complex)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016235"(aggresome)|go:"GO:0016236"(macroautophagy)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0019900"(kinase binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035973"(aggrephagy)|go:"GO:0042802"(identical protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0097352"(autophagosome maturation)|go:"GO:1901340"(negative regulation of store-operated calcium channel activity)|go:"GO:1902175"(regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)|interpro:IPR000626(Ubiquitin)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR028430|interpro:IPR029071|mint:Q9UMX0|rcsb pdb:2JY5|rcsb pdb:2JY6|rcsb pdb:2KLC|reactome:R-HSA-8856825|refseq:NP_038466.2|refseq:NP_444295.1|dip:DIP-41629N|entrezgene/locuslink:29979(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:olrpTXf4PLFKXG++Rcnf3PlDjLM559292	rogid:nCFfZbGCTvRYaXhQ4R99XblslvM9606	intact-crc:0B20D51DC74BA661|rigid:XtkcU8jqAgTu14EfwtOcBwul8ZE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96DZ9-2	uniprotkb:Q02724	intact:EBI-11522780|ensembl:ENSP00000352270|ensembl:ENSP00000497215	intact:EBI-20050|uniprotkb:D6W3Z2|ensemblfungi:YPL020C	psi-mi:q96dz9-2(display_long)|uniprotkb:CMTM5(gene name)|psi-mi:CMTM5(display_short)|uniprotkb:CKLFSF5(gene name synonym)|uniprotkb:Chemokine-like factor superfamily member 5(gene name synonym)	psi-mi:ulp1_yeast(display_long)|uniprotkb:ULP1(gene name)|psi-mi:ULP1(display_short)|uniprotkb:LPB11C(orf name)|uniprotkb:YPL020C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11544799|imex:IM-24995-2368	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000166091(gene)|ensembl:ENST00000359320(transcript)|ensembl:ENST00000649278(transcript)|intact:EBI-2548702(isoform-parent)|uniprotkb:Q96DZ9-2(isoform-parent)|entrezgene/locuslink:116173(identity)	refseq:NP_015305.1|sgd:S000005941|ensemblfungi:YPL020C(gene)|ensemblfungi:YPL020C_mRNA(transcript)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005730"(nucleolus)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0016926"(protein desumoylation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070140"(SUMO-specific isopeptidase activity)|interpro:IPR003653(Peptidase C48, SUMO/Sentrin/Ubl1)|interpro:IPR038765|rcsb pdb:1EUV|rcsb pdb:2HKP|rcsb pdb:2HL8|rcsb pdb:2HL9|rcsb pdb:5H2V|rcsb pdb:5H2W|rcsb pdb:5H2X|reactome:R-SCE-3065679|reactome:R-SCE-6791226|dip:DIP-4041N|mint:Q02724|sgd:YPL020C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:2TJ7rZKQNb5hH5gz9i+ujOEOIOg9606	rogid:H9B4qZf/ZMbHr7u4hbtR4fzz0ec559292	intact-crc:ECBFFE0EFAD0EA4D|rigid:bA9ChALF2ya3z9shfdEU0Vaxy9Q	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q02724	uniprotkb:Q8NHQ1	intact:EBI-20050|uniprotkb:D6W3Z2|ensemblfungi:YPL020C	intact:EBI-739624|ensembl:ENSP00000264982|ensembl:ENSP00000419231|uniprotkb:Q96B31|uniprotkb:Q9H2C3|uniprotkb:Q9H2Z1|uniprotkb:Q9H940|uniprotkb:D3DNE9|uniprotkb:B7Z5I8|uniprotkb:B7Z7E8|uniprotkb:F5GZX8	psi-mi:ulp1_yeast(display_long)|uniprotkb:ULP1(gene name)|psi-mi:ULP1(display_short)|uniprotkb:LPB11C(orf name)|uniprotkb:YPL020C(locus name)	psi-mi:cep70_human(display_long)|uniprotkb:CEP70(gene name)|psi-mi:CEP70(display_short)|uniprotkb:BITE(gene name synonym)|uniprotkb:p10-binding protein(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11544790|imex:IM-24995-2367	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015305.1|sgd:S000005941|ensemblfungi:YPL020C(gene)|ensemblfungi:YPL020C_mRNA(transcript)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005730"(nucleolus)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0016926"(protein desumoylation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070140"(SUMO-specific isopeptidase activity)|interpro:IPR003653(Peptidase C48, SUMO/Sentrin/Ubl1)|interpro:IPR038765|rcsb pdb:1EUV|rcsb pdb:2HKP|rcsb pdb:2HL8|rcsb pdb:2HL9|rcsb pdb:5H2V|rcsb pdb:5H2W|rcsb pdb:5H2X|reactome:R-SCE-3065679|reactome:R-SCE-6791226|dip:DIP-4041N|mint:Q02724|sgd:YPL020C(identity)	ensembl:ENSG00000114107(gene)|ensembl:ENST00000264982(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|interpro:IPR019734|interpro:IPR037692|mint:Q8NHQ1|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|ensembl:ENST00000484888(transcript)|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_077817.2|refseq:XP_016862764.1|refseq:NP_001275893.1|refseq:NP_001275894.1|refseq:NP_001275895.1|refseq:NP_001275896.1|refseq:NP_001307527.1|refseq:NP_001307529.1|entrezgene/locuslink:80321(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:H9B4qZf/ZMbHr7u4hbtR4fzz0ec559292	rogid:S4yveQWcvdVtAUX65gqrJ5Dv0Mc9606	intact-crc:8C9873D9517B76FA|rigid:f93dJ2zT3oTwvFJuKkqvhFFZJkU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q02821	uniprotkb:A0A0C4DGF1	intact:EBI-1797|uniprotkb:D6W0Z8|ensemblfungi:YNL189W	intact:EBI-10188476|ensembl:ENSP00000433657	psi-mi:ima1_yeast(display_long)|uniprotkb:SRP1(gene name)|psi-mi:SRP1(display_short)|uniprotkb:KAP60(gene name synonym)|uniprotkb:YNL189W(locus name)|uniprotkb:N1606(orf name)|uniprotkb:Karyopherin subunit alpha(gene name synonym)|uniprotkb:Karyopherin-60(gene name synonym)|uniprotkb:Serine-rich RNA polymerase I suppressor protein(gene name synonym)	psi-mi:a0a0c4dgf1_human(display_long)|uniprotkb:ZBTB32(gene name)|psi-mi:ZBTB32(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11544862|imex:IM-24995-2375	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014210.1|sgd:S000005133|dip:DIP-728N|mint:Q02821|ensemblfungi:YNL189W(gene)|ensemblfungi:YNL189W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0031144"(proteasome localization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042564"(NLS-dependent protein nuclear import complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|rcsb pdb:1BK5|rcsb pdb:1BK6|rcsb pdb:1EE4|rcsb pdb:1EE5|rcsb pdb:1UN0|rcsb pdb:1WA5|rcsb pdb:2C1T|rcsb pdb:4PVZ|rcsb pdb:4XZR|rcsb pdb:5H2W|rcsb pdb:5H2X|rcsb pdb:5T94|sgd:YNL189W(identity)	interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|ensembl:ENSG00000011590(gene)|ensembl:ENST00000481182(transcript)|go:"GO:0042802"(identical protein binding)|entrezgene/locuslink:27033(identity)	-	crc64:8D3A0CB76F2E7C00	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:NyzC93xnBCb8DX/AH346lwg4u2A559292	rogid:w3k7YT4kw/T+Xi5YBqGHSpHtwMM9606	intact-crc:709EE3525707DDA3|rigid:SJnLFil/JKxND/k7uaUdrRDCNwE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96A10	uniprotkb:Q02821	intact:EBI-10486892|intact:EBI-11528237|ensembl:ENSP00000488921	intact:EBI-1797|uniprotkb:D6W0Z8|ensemblfungi:YNL189W	psi-mi:q96a10_human(display_long)|uniprotkb:ERVK3-1(gene name)|psi-mi:ERVK3-1(display_short)|uniprotkb:hCG_2043597(orf name)	psi-mi:ima1_yeast(display_long)|uniprotkb:SRP1(gene name)|psi-mi:SRP1(display_short)|uniprotkb:KAP60(gene name synonym)|uniprotkb:YNL189W(locus name)|uniprotkb:N1606(orf name)|uniprotkb:Karyopherin subunit alpha(gene name synonym)|uniprotkb:Karyopherin-60(gene name synonym)|uniprotkb:Serine-rich RNA polymerase I suppressor protein(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11544853|imex:IM-24995-2374	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000142396(gene)|ensembl:ENST00000427361(transcript)|entrezgene/locuslink:113386(identity)	refseq:NP_014210.1|sgd:S000005133|dip:DIP-728N|mint:Q02821|ensemblfungi:YNL189W(gene)|ensemblfungi:YNL189W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0031144"(proteasome localization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042564"(NLS-dependent protein nuclear import complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|rcsb pdb:1BK5|rcsb pdb:1BK6|rcsb pdb:1EE4|rcsb pdb:1EE5|rcsb pdb:1UN0|rcsb pdb:1WA5|rcsb pdb:2C1T|rcsb pdb:4PVZ|rcsb pdb:4XZR|rcsb pdb:5H2W|rcsb pdb:5H2X|rcsb pdb:5T94|sgd:YNL189W(identity)	-	-	crc64:8D3A0CB76F2E7C00	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/17	rogid:UGl9ZpnDNz58eECRstJXxM5bj9I9606	rogid:NyzC93xnBCb8DX/AH346lwg4u2A559292	intact-crc:E70279853FB69A7C|rigid:PfXqrP00JKkZ9DrWN17KbMlKCFg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q02793	uniprotkb:Q5D1E8	intact:EBI-17260|uniprotkb:D6VTU2|ensemblfungi:YGL213C	intact:EBI-747793|uniprotkb:Q6I9Z1|uniprotkb:Q9H5P1|uniprotkb:D3DPT0|ensembl:ENSP00000362179	psi-mi:ski8_yeast(display_long)|uniprotkb:YGL213C(locus name)|uniprotkb:SKI8(gene name)|psi-mi:SKI8(display_short)|uniprotkb:REC103(gene name synonym)|uniprotkb:Superkiller protein 8(gene name synonym)	psi-mi:zc12a_human(display_long)|uniprotkb:MCPIP(gene name synonym)|uniprotkb:MCPIP1(gene name synonym)|uniprotkb:ZC3H12A(gene name)|psi-mi:ZC3H12A(display_short)|uniprotkb:Monocyte chemotactic protein-induced protein 1(gene name synonym)|uniprotkb:Regnase-1(gene name synonym)|uniprotkb:Zinc finger CCCH domain-containing protein 12A(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11544844|imex:IM-24995-2373	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011302.1|sgd:S000003181|ensemblfungi:YGL213C(gene)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034622"|go:"GO:0051607"(defense response to virus)|go:"GO:0055087"(Ski complex)|go:"GO:0065004"(protein-DNA complex assembly)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|rcsb pdb:1S4U|rcsb pdb:1SQ9|rcsb pdb:4BUJ|rcsb pdb:5MC6|reactome:R-SCE-429958|reactome:R-SCE-674695|reactome:R-SCE-75955|ensemblfungi:YGL213C_mRNA(transcript)|dip:DIP-1653N|mint:Q02793|sgd:YGL213C(identity)	refseq:NP_079355.2|refseq:NP_001310479.1|ensembl:ENSG00000163874(gene)|ensembl:ENST00000373087(transcript)|go:"GO:0000294"(nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay)|go:"GO:0000932"(P-body)|go:"GO:0001525"(angiogenesis)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0002757"(immune response-activating signal transduction)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0004532"(exoribonuclease activity)|go:"GO:0004540"(ribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007399"(nervous system development)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010656"(negative regulation of muscle cell apoptotic process)|go:"GO:0010884"(positive regulation of lipid storage)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0030154"(cell differentiation)|go:"GO:0030867"(rough endoplasmic reticulum membrane)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032691"(negative regulation of interleukin-1 beta production)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035198"(miRNA binding)|go:"GO:0035613"(RNA stem-loop binding)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042406"(extrinsic component of endoplasmic reticulum membrane)|go:"GO:0043022"(ribosome binding)|go:"GO:0043031"(negative regulation of macrophage activation)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0044828"(negative regulation by host of viral genome replication)|go:"GO:0045019"(negative regulation of nitric oxide biosynthetic process)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051607"(defense response to virus)|go:"GO:0055118"(negative regulation of cardiac muscle contraction)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0090501"(RNA phosphodiester bond hydrolysis)|go:"GO:0090502"(RNA phosphodiester bond hydrolysis, endonucleolytic)|go:"GO:0098586"(cellular response to virus)|go:"GO:1900016"(negative regulation of cytokine production involved in inflammatory response)|go:"GO:1900119"(positive regulation of execution phase of apoptosis)|go:"GO:1901223"(negative regulation of NIK/NF-kappaB signaling)|go:"GO:1903003"(positive regulation of protein deubiquitination)|go:"GO:1903799"(negative regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1903936"(cellular response to sodium arsenite)|go:"GO:1904637"(cellular response to ionomycin)|go:"GO:1990869"(cellular response to chemokine)|go:"GO:2000320"(negative regulation of T-helper 17 cell differentiation)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|go:"GO:2000627"(positive regulation of miRNA catabolic process)|interpro:IPR021869|interpro:IPR040546|interpro:IPR040757|rcsb pdb:3V32|rcsb pdb:3V33|rcsb pdb:3V34|go:"GO:1900745"(positive regulation of p38MAPK cascade)|entrezgene/locuslink:80149(identity)	-	crc64:C5E7B9D2268F9727	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:6K6FJYcctdlT1321Nv6pOnQPwq8559292	rogid:3FqqH/XrYjHaa5oJpPXvfYwHKCQ9606	intact-crc:3DACF6AE0EAD03F9|rigid:BYi2vr6auPKAMD8M263RLfI4o+4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q02793	uniprotkb:P38432	intact:EBI-17260|uniprotkb:D6VTU2|ensemblfungi:YGL213C	intact:EBI-945751|uniprotkb:B2R931|ensembl:ENSP00000240316	psi-mi:ski8_yeast(display_long)|uniprotkb:YGL213C(locus name)|uniprotkb:SKI8(gene name)|psi-mi:SKI8(display_short)|uniprotkb:REC103(gene name synonym)|uniprotkb:Superkiller protein 8(gene name synonym)	psi-mi:coil_human(display_long)|uniprotkb:COIL(gene name)|psi-mi:COIL(display_short)|uniprotkb:CLN80(gene name synonym)|uniprotkb:p80-coilin(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11544835|imex:IM-24995-2372	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011302.1|sgd:S000003181|ensemblfungi:YGL213C(gene)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034622"|go:"GO:0051607"(defense response to virus)|go:"GO:0055087"(Ski complex)|go:"GO:0065004"(protein-DNA complex assembly)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|rcsb pdb:1S4U|rcsb pdb:1SQ9|rcsb pdb:4BUJ|rcsb pdb:5MC6|reactome:R-SCE-429958|reactome:R-SCE-674695|reactome:R-SCE-75955|ensemblfungi:YGL213C_mRNA(transcript)|dip:DIP-1653N|mint:Q02793|sgd:YGL213C(identity)	refseq:NP_004636.1|dip:DIP-38503N|ensembl:ENSG00000121058(gene)|ensembl:ENST00000240316(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0015030"(Cajal body)|go:"GO:0016020"(membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0030619"(U1 snRNA binding)|go:"GO:0030620"(U2 snRNA binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR024822|interpro:IPR031722|mint:P38432|entrezgene/locuslink:8161(identity)	-	crc64:C5E7B9D2268F9727	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:6K6FJYcctdlT1321Nv6pOnQPwq8559292	rogid:hd5p6AbyA/GYNEeca99Mdb41qM09606	intact-crc:58EB3EF775CC35EB|rigid:ABp9irOa3eI3gW27e08nrIbXS78	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P20591	uniprotkb:Q02821	intact:EBI-929476|uniprotkb:D3DSI8|uniprotkb:B2RDA5|uniprotkb:B3KU10|uniprotkb:C9IYV7|uniprotkb:C9J8D6|uniprotkb:C9JN19|uniprotkb:C9JN88|uniprotkb:C9JUL1|uniprotkb:C9JZS6|uniprotkb:Q86YP5|uniprotkb:Q96CI3|ensembl:ENSP00000381599|ensembl:ENSP00000381601|ensembl:ENSP00000392151|ensembl:ENSP00000402215|ensembl:ENSP00000408498|ensembl:ENSP00000410523|ensembl:ENSP00000505029|ensembl:ENSP00000505047|ensembl:ENSP00000505051|ensembl:ENSP00000505189|ensembl:ENSP00000505457|ensembl:ENSP00000505489|ensembl:ENSP00000505630|ensembl:ENSP00000505657|ensembl:ENSP00000505669|ensembl:ENSP00000505781|ensembl:ENSP00000505874|ensembl:ENSP00000506047|ensembl:ENSP00000506062|ensembl:ENSP00000506183|ensembl:ENSP00000506199|ensembl:ENSP00000506220|ensembl:ENSP00000506270|ensembl:ENSP00000506348|ensembl:ENSP00000506372|ensembl:ENSP00000506395|ensembl:ENSP00000506481|ensembl:ENSP00000506512|ensembl:ENSP00000506690|ensembl:ENSP00000506712	intact:EBI-1797|uniprotkb:D6W0Z8|ensemblfungi:YNL189W	psi-mi:mx1_human(display_long)|uniprotkb:MX1(gene name)|psi-mi:MX1(display_short)|uniprotkb:Myxovirus resistance protein 1(gene name synonym)|uniprotkb:Interferon-regulated resistance GTP-binding protein MxA(gene name synonym)|uniprotkb:Interferon-induced protein p78(gene name synonym)|uniprotkb:Myxoma resistance protein 1(gene name synonym)	psi-mi:ima1_yeast(display_long)|uniprotkb:SRP1(gene name)|psi-mi:SRP1(display_short)|uniprotkb:KAP60(gene name synonym)|uniprotkb:YNL189W(locus name)|uniprotkb:N1606(orf name)|uniprotkb:Karyopherin subunit alpha(gene name synonym)|uniprotkb:Karyopherin-60(gene name synonym)|uniprotkb:Serine-rich RNA polymerase I suppressor protein(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11544900|imex:IM-24995-2379	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001269849.1|refseq:NP_001138397.1|refseq:NP_001171517.1|refseq:NP_002453.2|refseq:XP_011527870.1|refseq:XP_005261037.1|refseq:XP_005261038.1|refseq:XP_005261039.1|refseq:XP_005261035.1|refseq:XP_005261036.1|refseq:XP_016883838.1|refseq:XP_016883839.1|dip:DIP-35694N|ensembl:ENSG00000157601(gene)|ensembl:ENST00000398598(transcript)|ensembl:ENST00000398600(transcript)|ensembl:ENST00000413778(transcript)|ensembl:ENST00000417963(transcript)|ensembl:ENST00000419044(transcript)|ensembl:ENST00000455164(transcript)|ensembl:ENST00000679445(transcript)|ensembl:ENST00000679464(transcript)|ensembl:ENST00000679543(transcript)|ensembl:ENST00000679626(transcript)|ensembl:ENST00000679705(transcript)|ensembl:ENST00000679911(transcript)|ensembl:ENST00000680176(transcript)|ensembl:ENST00000680182(transcript)|ensembl:ENST00000680347(transcript)|ensembl:ENST00000680364(transcript)|ensembl:ENST00000680536(transcript)|ensembl:ENST00000680629(transcript)|ensembl:ENST00000680760(transcript)|ensembl:ENST00000680776(transcript)|ensembl:ENST00000681039(transcript)|ensembl:ENST00000681191(transcript)|ensembl:ENST00000681266(transcript)|ensembl:ENST00000681415(transcript)|ensembl:ENST00000681607(transcript)|ensembl:ENST00000681671(transcript)|ensembl:ENST00000681849(transcript)|ensembl:ENST00000681857(transcript)|ensembl:ENST00000681867(transcript)|ensembl:ENST00000681896(transcript)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0003374"(dynamin family protein polymerization involved in mitochondrial fission)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0006952"(defense response)|go:"GO:0007165"(signal transduction)|go:"GO:0008017"(microtubule binding)|go:"GO:0009615"(response to virus)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016185"(synaptic vesicle budding from presynaptic endocytic zone membrane)|go:"GO:0030424"(axon)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031623"(receptor internalization)|go:"GO:0031965"(nuclear membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0034340"(response to type I interferon)|go:"GO:0042802"(identical protein binding)|go:"GO:0044327"(dendritic spine head)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0051607"(defense response to virus)|go:"GO:0061025"(membrane fusion)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:0098793"(presynapse)|go:"GO:0098844"(postsynaptic endocytic zone membrane)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:0140374"(antiviral innate immune response)|interpro:IPR000375(Dynamin central region)|interpro:IPR001401(Dynamin, GTPase region)|interpro:IPR003130(Dynamin GTPase effector)|interpro:IPR019762|interpro:IPR020850|interpro:IPR022812|interpro:IPR027417|interpro:IPR030381|mint:P20591|rcsb pdb:3LJB|rcsb pdb:3SZR|rcsb pdb:3ZYS|rcsb pdb:4P4S|rcsb pdb:4P4T|rcsb pdb:4P4U|rcsb pdb:5GTM|reactome:R-HSA-1169408|reactome:R-HSA-909733|entrezgene/locuslink:4599(identity)	refseq:NP_014210.1|sgd:S000005133|dip:DIP-728N|mint:Q02821|ensemblfungi:YNL189W(gene)|ensemblfungi:YNL189W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0031144"(proteasome localization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042564"(NLS-dependent protein nuclear import complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|rcsb pdb:1BK5|rcsb pdb:1BK6|rcsb pdb:1EE4|rcsb pdb:1EE5|rcsb pdb:1UN0|rcsb pdb:1WA5|rcsb pdb:2C1T|rcsb pdb:4PVZ|rcsb pdb:4XZR|rcsb pdb:5H2W|rcsb pdb:5H2X|rcsb pdb:5T94|sgd:YNL189W(identity)	-	-	crc64:8D3A0CB76F2E7C00	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:9rO7Zyl6v0Kq3xw6MKbVefk1hCA9606	rogid:NyzC93xnBCb8DX/AH346lwg4u2A559292	intact-crc:0906EB657D61C889|rigid:Ss/YtFxCh1OwLwdQC3gxslONYCc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q02821	uniprotkb:P13196	intact:EBI-1797|uniprotkb:D6W0Z8|ensemblfungi:YNL189W	intact:EBI-3905054|ensembl:ENSP00000309259|ensembl:ENSP00000378416|ensembl:ENSP00000417719|ensembl:ENSP00000418779	psi-mi:ima1_yeast(display_long)|uniprotkb:SRP1(gene name)|psi-mi:SRP1(display_short)|uniprotkb:KAP60(gene name synonym)|uniprotkb:YNL189W(locus name)|uniprotkb:N1606(orf name)|uniprotkb:Karyopherin subunit alpha(gene name synonym)|uniprotkb:Karyopherin-60(gene name synonym)|uniprotkb:Serine-rich RNA polymerase I suppressor protein(gene name synonym)	psi-mi:hem1_human(display_long)|uniprotkb:ALAS1(gene name)|psi-mi:ALAS1(display_short)|uniprotkb:ALAS3(gene name synonym)|uniprotkb:ALASH(gene name synonym)|uniprotkb:5-aminolevulinic acid synthase 1(gene name synonym)|uniprotkb:Delta-ALA synthase 1(gene name synonym)|uniprotkb:Delta-aminolevulinate synthase 1(gene name synonym)|uniprotkb:OK/SW-cl.121(orf name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11544891|imex:IM-24995-2378	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014210.1|sgd:S000005133|dip:DIP-728N|mint:Q02821|ensemblfungi:YNL189W(gene)|ensemblfungi:YNL189W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0031144"(proteasome localization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042564"(NLS-dependent protein nuclear import complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|rcsb pdb:1BK5|rcsb pdb:1BK6|rcsb pdb:1EE4|rcsb pdb:1EE5|rcsb pdb:1UN0|rcsb pdb:1WA5|rcsb pdb:2C1T|rcsb pdb:4PVZ|rcsb pdb:4XZR|rcsb pdb:5H2W|rcsb pdb:5H2X|rcsb pdb:5T94|sgd:YNL189W(identity)	refseq:NP_001291372.1|refseq:NP_001291373.1|refseq:NP_000679.1|refseq:NP_954635.1|go:"GO:0006783"(heme biosynthetic process)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0042541"(hemoglobin biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0048821"(erythrocyte development)|ensembl:ENSG00000023330(gene)|ensembl:ENST00000310271(transcript)|ensembl:ENST00000394965(transcript)|ensembl:ENST00000469224(transcript)|ensembl:ENST00000484952(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0003870"(5-aminolevulinate synthase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|interpro:IPR001917(Aminotransferase, class-II, pyridoxal-phosphate binding site)|interpro:IPR004839(Aminotransferase, class I and II)|interpro:IPR010961(Tetrapyrrole biosynthesis, 5-aminolevulinic acid synthase)|interpro:IPR015118(5-aminolevulinate synthase presequence)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|mint:P13196|reactome:R-HSA-189451|reactome:R-HSA-1989781|reactome:R-HSA-2151201|go:"GO:0006782"(protoporphyrinogen IX biosynthetic process)|entrezgene/locuslink:211(identity)	-	crc64:8D3A0CB76F2E7C00	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:NyzC93xnBCb8DX/AH346lwg4u2A559292	rogid:HFjJ6zrRF9UYD7LMB6A3CcxcS7c9606	intact-crc:7F77295EC2686221|rigid:I1igYh7FqhViL3owJKuaKs/NN4g	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O00635	uniprotkb:Q02821	intact:EBI-2130415|uniprotkb:B2R862|ensembl:ENSP00000349596	intact:EBI-1797|uniprotkb:D6W0Z8|ensemblfungi:YNL189W	psi-mi:tri38_human(display_long)|uniprotkb:TRIM38(gene name)|psi-mi:TRIM38(display_short)|uniprotkb:RNF15(gene name synonym)|uniprotkb:RORET(gene name synonym)|uniprotkb:RING finger protein 15(gene name synonym)|uniprotkb:Zinc finger protein RoRet(gene name synonym)|uniprotkb:Tripartite motif-containing protein 38(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM38(gene name synonym)	psi-mi:ima1_yeast(display_long)|uniprotkb:SRP1(gene name)|psi-mi:SRP1(display_short)|uniprotkb:KAP60(gene name synonym)|uniprotkb:YNL189W(locus name)|uniprotkb:N1606(orf name)|uniprotkb:Karyopherin subunit alpha(gene name synonym)|uniprotkb:Karyopherin-60(gene name synonym)|uniprotkb:Serine-rich RNA polymerase I suppressor protein(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11544882|imex:IM-24995-2377	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006346.1|refseq:XP_005248856.1|refseq:XP_005248857.1|ensembl:ENSG00000112343(gene)|ensembl:ENST00000357085(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046598"(positive regulation of viral entry into host cell)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR035790|interpro:IPR043136|reactome:R-HSA-877300|entrezgene/locuslink:10475(identity)	refseq:NP_014210.1|sgd:S000005133|dip:DIP-728N|mint:Q02821|ensemblfungi:YNL189W(gene)|ensemblfungi:YNL189W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0031144"(proteasome localization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042564"(NLS-dependent protein nuclear import complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|rcsb pdb:1BK5|rcsb pdb:1BK6|rcsb pdb:1EE4|rcsb pdb:1EE5|rcsb pdb:1UN0|rcsb pdb:1WA5|rcsb pdb:2C1T|rcsb pdb:4PVZ|rcsb pdb:4XZR|rcsb pdb:5H2W|rcsb pdb:5H2X|rcsb pdb:5T94|sgd:YNL189W(identity)	-	-	crc64:8D3A0CB76F2E7C00	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Zh4X/6v/qKZlDkMV6hhn7OsvPnQ9606	rogid:NyzC93xnBCb8DX/AH346lwg4u2A559292	intact-crc:C37AE76055E05B3E|rigid:oSEeJqNHyIdmz0zFygbv5rM4TXg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q02821	uniprotkb:Q7Z6G3-2	intact:EBI-1797|uniprotkb:D6W0Z8|ensemblfungi:YNL189W	intact:EBI-10172876|ensembl:ENSP00000457354|intact:EBI-14062040	psi-mi:ima1_yeast(display_long)|uniprotkb:SRP1(gene name)|psi-mi:SRP1(display_short)|uniprotkb:KAP60(gene name synonym)|uniprotkb:YNL189W(locus name)|uniprotkb:N1606(orf name)|uniprotkb:Karyopherin subunit alpha(gene name synonym)|uniprotkb:Karyopherin-60(gene name synonym)|uniprotkb:Serine-rich RNA polymerase I suppressor protein(gene name synonym)	psi-mi:q7z6g3-2(display_long)|uniprotkb:EFCBP2(gene name synonym)|uniprotkb:Neuronal calcium-binding protein 2(gene name synonym)|uniprotkb:Synaptotagmin-interacting protein 2(gene name synonym)|uniprotkb:NECAB2(gene name)|psi-mi:NECAB2(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11544871|imex:IM-24995-2376	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014210.1|sgd:S000005133|dip:DIP-728N|mint:Q02821|ensemblfungi:YNL189W(gene)|ensemblfungi:YNL189W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0031144"(proteasome localization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042564"(NLS-dependent protein nuclear import complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|rcsb pdb:1BK5|rcsb pdb:1BK6|rcsb pdb:1EE4|rcsb pdb:1EE5|rcsb pdb:1UN0|rcsb pdb:1WA5|rcsb pdb:2C1T|rcsb pdb:4PVZ|rcsb pdb:4XZR|rcsb pdb:5H2W|rcsb pdb:5H2X|rcsb pdb:5T94|sgd:YNL189W(identity)	ensembl:ENSG00000103154(gene)|ensembl:ENST00000565691(transcript)|uniprotkb:Q7Z6G3-2(isoform-parent)|intact:EBI-950070(isoform-parent)|entrezgene/locuslink:54550(identity)	-	crc64:8D3A0CB76F2E7C00	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:NyzC93xnBCb8DX/AH346lwg4u2A559292	rogid:4S7oIx6h+mKzV3EPxqcfMNqaNko9606	intact-crc:5F370DB524B91CE0|rigid:hrdlqQvsmzhYRpTN4bYczcX5pEA	false	-	sufficient binding region:65-303	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q13137	uniprotkb:Q02821	intact:EBI-739580|uniprotkb:B4DDC4|uniprotkb:E7ENK0|uniprotkb:Q53FQ5|uniprotkb:Q53HB5|uniprotkb:Q6IBN9|uniprotkb:Q9BTF7|uniprotkb:B2RBT0|ensembl:ENSP00000258947|uniprotkb:B4E0C0|uniprotkb:E7ETP5|uniprotkb:B4DDT4|uniprotkb:B4DP36|uniprotkb:E9PBE5	intact:EBI-1797|uniprotkb:D6W0Z8|ensemblfungi:YNL189W	psi-mi:caco2_human(display_long)|uniprotkb:CALCOCO2(gene name)|psi-mi:CALCOCO2(display_short)|uniprotkb:NDP52(gene name synonym)|uniprotkb:Nuclear domain 10 protein NDP52(gene name synonym)|uniprotkb:Antigen nuclear dot 52 kDa protein(gene name synonym)|uniprotkb:Nuclear dot protein 52(gene name synonym)	psi-mi:ima1_yeast(display_long)|uniprotkb:SRP1(gene name)|psi-mi:SRP1(display_short)|uniprotkb:KAP60(gene name synonym)|uniprotkb:YNL189W(locus name)|uniprotkb:N1606(orf name)|uniprotkb:Karyopherin subunit alpha(gene name synonym)|uniprotkb:Karyopherin-60(gene name synonym)|uniprotkb:Serine-rich RNA polymerase I suppressor protein(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11544948|imex:IM-24995-2384	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001248319.1|refseq:NP_001248320.1|refseq:NP_001248322.1|refseq:NP_005822.1|ensembl:ENSG00000136436(gene)|ensembl:ENST00000258947(transcript)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016032"(viral process)|go:"GO:0016605"(PML body)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0098792"(xenophagy)|go:"GO:1901098"(positive regulation of autophagosome maturation)|interpro:IPR041611|interpro:IPR041641|mint:Q13137|rcsb pdb:2MXP|rcsb pdb:3VVV|rcsb pdb:3VVW|rcsb pdb:4GXL|rcsb pdb:4HAN|rcsb pdb:4XKL|rcsb pdb:5AAQ|rcsb pdb:5Z7A|rcsb pdb:5Z7L|refseq:NP_001248324.1|dip:DIP-57534N|entrezgene/locuslink:10241(identity)	refseq:NP_014210.1|sgd:S000005133|dip:DIP-728N|mint:Q02821|ensemblfungi:YNL189W(gene)|ensemblfungi:YNL189W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0031144"(proteasome localization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042564"(NLS-dependent protein nuclear import complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|rcsb pdb:1BK5|rcsb pdb:1BK6|rcsb pdb:1EE4|rcsb pdb:1EE5|rcsb pdb:1UN0|rcsb pdb:1WA5|rcsb pdb:2C1T|rcsb pdb:4PVZ|rcsb pdb:4XZR|rcsb pdb:5H2W|rcsb pdb:5H2X|rcsb pdb:5T94|sgd:YNL189W(identity)	-	crc64:609B121DA1A9DCB8	crc64:8D3A0CB76F2E7C00	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:N/GPJUGBK+Dh5Cg+csmafphuo9M9606	rogid:NyzC93xnBCb8DX/AH346lwg4u2A559292	intact-crc:62F98FA1DBC936E7|rigid:hHMSqSo0VC7VlXnaDmX0YbMFn94	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q02821	uniprotkb:P63261	intact:EBI-1797|uniprotkb:D6W0Z8|ensemblfungi:YNL189W	intact:EBI-351292|uniprotkb:P02571|uniprotkb:P14104|uniprotkb:P99022|uniprotkb:Q5U032|uniprotkb:Q96E67|uniprotkb:A8K7C2|ensembl:ENSP00000505060|ensembl:ENSP00000505193|ensembl:ENSP00000505235|ensembl:ENSP00000506126|ensembl:ENSP00000506201|ensembl:ENSP00000506253|ensembl:ENSP00000458162|ensembl:ENSP00000458435|ensembl:ENSP00000459119|ensembl:ENSP00000459124|ensembl:ENSP00000460464|ensembl:ENSP00000460660|ensembl:ENSP00000461672|ensembl:ENSP00000466346|ensembl:ENSP00000477968	psi-mi:ima1_yeast(display_long)|uniprotkb:SRP1(gene name)|psi-mi:SRP1(display_short)|uniprotkb:KAP60(gene name synonym)|uniprotkb:YNL189W(locus name)|uniprotkb:N1606(orf name)|uniprotkb:Karyopherin subunit alpha(gene name synonym)|uniprotkb:Karyopherin-60(gene name synonym)|uniprotkb:Serine-rich RNA polymerase I suppressor protein(gene name synonym)	psi-mi:actg_human(display_long)|uniprotkb:ACTG1(gene name)|psi-mi:ACTG1(display_short)|uniprotkb:ACTG(gene name synonym)|uniprotkb:Gamma-actin(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11544938|imex:IM-24995-2383	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014210.1|sgd:S000005133|dip:DIP-728N|mint:Q02821|ensemblfungi:YNL189W(gene)|ensemblfungi:YNL189W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0031144"(proteasome localization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042564"(NLS-dependent protein nuclear import complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|rcsb pdb:1BK5|rcsb pdb:1BK6|rcsb pdb:1EE4|rcsb pdb:1EE5|rcsb pdb:1UN0|rcsb pdb:1WA5|rcsb pdb:2C1T|rcsb pdb:4PVZ|rcsb pdb:4XZR|rcsb pdb:5H2W|rcsb pdb:5H2X|rcsb pdb:5T94|sgd:YNL189W(identity)	refseq:NP_001186883.1|refseq:NP_001605.1|ensembl:ENST00000570382(transcript)|ensembl:ENSG00000184009(gene)|ensembl:ENST00000571721(transcript)|ensembl:ENST00000573283(transcript)|ensembl:ENST00000575087(transcript)|ensembl:ENST00000575659(transcript)|ensembl:ENST00000575842(transcript)|ensembl:ENST00000575994(transcript)|ensembl:ENST00000576544(transcript)|ensembl:ENST00000615544(transcript)|ensembl:ENST00000679480(transcript)|ensembl:ENST00000679778(transcript)|ensembl:ENST00000680227(transcript)|ensembl:ENST00000680727(transcript)|ensembl:ENST00000681052(transcript)|ensembl:ENST00000681842(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0001895"(retina homeostasis)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005522"(profilin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0030016"(myofibril)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031941"(filamentous actin)|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0044305"(calyx of Held)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0051492"(regulation of stress fiber assembly)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070527"(platelet aggregation)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0072562"(blood microparticle)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0097433"(dense body)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098973"(structural constituent of postsynaptic actin cytoskeleton)|go:"GO:0120192"(tight junction assembly)|go:"GO:0120220"(basal body patch)|go:"GO:0150111"(regulation of transepithelial transport)|go:"GO:1902396"(protein localization to bicellular tight junction)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P63261|rcsb pdb:5JLH|rcsb pdb:6CXI|rcsb pdb:6CXJ|rcsb pdb:6G2T|rcsb pdb:6V62|rcsb pdb:6V63|rcsb pdb:6WK1|rcsb pdb:6WK2|reactome:R-HSA-1445148|reactome:R-HSA-190873|reactome:R-HSA-196025|reactome:R-HSA-2029482|reactome:R-HSA-3928662|reactome:R-HSA-3928665|reactome:R-HSA-418990|reactome:R-HSA-437239|reactome:R-HSA-4420097|reactome:R-HSA-445095|reactome:R-HSA-446353|reactome:R-HSA-5626467|reactome:R-HSA-5663213|reactome:R-HSA-5663220|reactome:R-HSA-5674135|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8856828|reactome:R-HSA-9013418|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9662360|reactome:R-HSA-9662361|reactome:R-HSA-9664422|entrezgene/locuslink:71(identity)	-	crc64:8D3A0CB76F2E7C00	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:NyzC93xnBCb8DX/AH346lwg4u2A559292	rogid:B2OOsE06lTfo90H3g8tlmUJQ7cY9606	intact-crc:58AD7E57FB740EED|rigid:eAmSecUW+kV9D40b0fX57lQh+ZU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q02821	uniprotkb:P60709	intact:EBI-1797|uniprotkb:D6W0Z8|ensemblfungi:YNL189W	intact:EBI-353944|uniprotkb:P02570|uniprotkb:P70514|uniprotkb:P99021|uniprotkb:Q11211|uniprotkb:Q64316|uniprotkb:Q75MN2|uniprotkb:Q96B34|uniprotkb:Q96HG5|ensembl:ENSP00000494269|ensembl:ENSP00000494750|ensembl:ENSP00000495995|ensembl:ENSP00000501862|ensembl:ENSP00000502821	psi-mi:ima1_yeast(display_long)|uniprotkb:SRP1(gene name)|psi-mi:SRP1(display_short)|uniprotkb:KAP60(gene name synonym)|uniprotkb:YNL189W(locus name)|uniprotkb:N1606(orf name)|uniprotkb:Karyopherin subunit alpha(gene name synonym)|uniprotkb:Karyopherin-60(gene name synonym)|uniprotkb:Serine-rich RNA polymerase I suppressor protein(gene name synonym)	psi-mi:actb_human(display_long)|uniprotkb:ACTB(gene name)|psi-mi:ACTB(display_short)|uniprotkb:Beta-actin(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11544928|imex:IM-24995-2382	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014210.1|sgd:S000005133|dip:DIP-728N|mint:Q02821|ensemblfungi:YNL189W(gene)|ensemblfungi:YNL189W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0031144"(proteasome localization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042564"(NLS-dependent protein nuclear import complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|rcsb pdb:1BK5|rcsb pdb:1BK6|rcsb pdb:1EE4|rcsb pdb:1EE5|rcsb pdb:1UN0|rcsb pdb:1WA5|rcsb pdb:2C1T|rcsb pdb:4PVZ|rcsb pdb:4XZR|rcsb pdb:5H2W|rcsb pdb:5H2X|rcsb pdb:5T94|sgd:YNL189W(identity)	refseq:NP_001092.1|ensembl:ENSG00000075624(gene)|ensembl:ENST00000493945(transcript)|ensembl:ENST00000642480(transcript)|ensembl:ENST00000646664(transcript)|ensembl:ENST00000674681(transcript)|ensembl:ENST00000675515(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000785"(chromatin)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0001895"(retina homeostasis)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007409"(axonogenesis)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019894"(kinesin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0022898"(regulation of transmembrane transporter activity)|go:"GO:0030027"(lamellipodium)|go:"GO:0030424"(axon)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0030957"(Tat protein binding)|go:"GO:0031982"(vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034333"(adherens junction assembly)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043044"|go:"GO:0043296"(apical junction complex)|go:"GO:0044305"(calyx of Held)|go:"GO:0045176"(apical protein localization)|go:"GO:0045202"(synapse)|go:"GO:0048156"(tau protein binding)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048870"(cell motility)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051621"(regulation of norepinephrine uptake)|go:"GO:0051623"(positive regulation of norepinephrine uptake)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070160"(tight junction)|go:"GO:0070527"(platelet aggregation)|reactome:R-HSA-4420097|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0072562"(blood microparticle)|go:"GO:0072749"(cellular response to cytochalasin B)|go:"GO:0097433"(dense body)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098973"(structural constituent of postsynaptic actin cytoskeleton)|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0150111"(regulation of transepithelial transport)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P60709|rcsb pdb:3BYH|rcsb pdb:3D2U|rcsb pdb:3J82|rcsb pdb:3LUE|rcsb pdb:6ANU|rcsb pdb:6ICT|rcsb pdb:6ICV|rcsb pdb:6LTJ|rcsb pdb:6MBJ|rcsb pdb:6MBK|rcsb pdb:6MBL|rcsb pdb:6NBW|rcsb pdb:6OX0|rcsb pdb:6OX1|rcsb pdb:6OX2|rcsb pdb:6OX3|rcsb pdb:6OX4|rcsb pdb:6OX5|rcsb pdb:6V62|rcsb pdb:6V63|rcsb pdb:6WK1|rcsb pdb:6WK2|rcsb pdb:7AS4|reactome:R-HSA-1445148|reactome:R-HSA-190873|reactome:R-HSA-196025|reactome:R-HSA-2029482|reactome:R-HSA-3214847|reactome:R-HSA-389957|reactome:R-HSA-390450|reactome:R-HSA-3928662|reactome:R-HSA-3928665|reactome:R-HSA-418990|reactome:R-HSA-437239|reactome:R-HSA-446353|reactome:R-HSA-5250924|reactome:R-HSA-5626467|reactome:R-HSA-5663213|reactome:R-HSA-5663220|reactome:R-HSA-5674135|reactome:R-HSA-5689603|reactome:R-HSA-5696394|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8856828|reactome:R-HSA-9035034|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9662360|reactome:R-HSA-9662361|reactome:R-HSA-9664422|reactome:R-HSA-983231|reactome:R-HSA-445095|dip:DIP-29686N|entrezgene/locuslink:60(identity)	-	crc64:8D3A0CB76F2E7C00	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:NyzC93xnBCb8DX/AH346lwg4u2A559292	rogid:Hoge1B8Pn56kvbNTpkSLsQuHwRc9606	intact-crc:C565A171D888D2B5|rigid:d5kT30yHU6iENIXi1DeN1T8yljU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q02821	uniprotkb:P35520	intact:EBI-1797|uniprotkb:D6W0Z8|ensemblfungi:YNL189W	intact:EBI-740135|uniprotkb:Q99425|uniprotkb:Q9BWC5|uniprotkb:B2R993|uniprotkb:D3DSK4|intact:EBI-14245939|ensembl:ENSP00000344460|ensembl:ENSP00000352643|ensembl:ENSP00000381225|ensembl:ENSP00000381231	psi-mi:ima1_yeast(display_long)|uniprotkb:SRP1(gene name)|psi-mi:SRP1(display_short)|uniprotkb:KAP60(gene name synonym)|uniprotkb:YNL189W(locus name)|uniprotkb:N1606(orf name)|uniprotkb:Karyopherin subunit alpha(gene name synonym)|uniprotkb:Karyopherin-60(gene name synonym)|uniprotkb:Serine-rich RNA polymerase I suppressor protein(gene name synonym)	psi-mi:cbs_human(display_long)|uniprotkb:CBS(gene name)|psi-mi:CBS(display_short)|uniprotkb:Serine sulfhydrase(gene name synonym)|uniprotkb:Beta-thionase(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11544918|imex:IM-24995-2381	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014210.1|sgd:S000005133|dip:DIP-728N|mint:Q02821|ensemblfungi:YNL189W(gene)|ensemblfungi:YNL189W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0031144"(proteasome localization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042564"(NLS-dependent protein nuclear import complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|rcsb pdb:1BK5|rcsb pdb:1BK6|rcsb pdb:1EE4|rcsb pdb:1EE5|rcsb pdb:1UN0|rcsb pdb:1WA5|rcsb pdb:2C1T|rcsb pdb:4PVZ|rcsb pdb:4XZR|rcsb pdb:5H2W|rcsb pdb:5H2X|rcsb pdb:5T94|sgd:YNL189W(identity)	refseq:NP_000062.1|refseq:NP_001171479.1|refseq:NP_001171480.1|ensembl:ENSG00000160200(gene)|ensembl:ENST00000352178(transcript)|ensembl:ENST00000359624(transcript)|ensembl:ENST00000398158(transcript)|go:"GO:0004122"(cystathionine beta-synthase activity)|ensembl:ENST00000398165(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006535"(cysteine biosynthetic process from serine)|go:"GO:0006563"(L-serine metabolic process)|go:"GO:0006565"(L-serine catabolic process)|go:"GO:0019343"(cysteine biosynthetic process via cystathionine)|go:"GO:0019344"(cysteine biosynthetic process)|go:"GO:0019346"(transsulfuration)|go:"GO:0019448"(L-cysteine catabolic process)|go:"GO:0019825"(oxygen binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0020037"(heme binding)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042262"(DNA protection)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043418"(homocysteine catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0050421"("nitrite reductase (NO-forming) activity")|go:"GO:0050667"(homocysteine metabolic process)|go:"GO:0070025"(carbon monoxide binding)|go:"GO:0070026"(nitric oxide binding)|go:"GO:0070814"(hydrogen sulfide biosynthetic process)|go:"GO:0072341"(modified amino acid binding)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR001216(Cysteine synthase/cystathionine beta-synthase P-phosphate-binding site)|interpro:IPR001926(Pyridoxal phosphate-dependent enzyme, beta subunit)|interpro:IPR005857(Cystathionine beta-synthase)|interpro:IPR036052|mint:P35520|rcsb pdb:1JBQ|rcsb pdb:1M54|rcsb pdb:4COO|rcsb pdb:4L0D|rcsb pdb:4L27|rcsb pdb:4L28|rcsb pdb:4L3V|rcsb pdb:4PCU|rcsb pdb:4UUU|rcsb pdb:5MMS|reactome:R-HSA-1614603|reactome:R-HSA-2408508|refseq:XP_011528079.1|refseq:XP_011528083.1|refseq:XP_011528084.1|refseq:XP_011544396.1|refseq:XP_011544397.1|refseq:XP_011544399.1|refseq:XP_011544400.1|refseq:XP_011544401.1|refseq:NP_001307227.1|refseq:NP_001308002.1|refseq:XP_016883700.1|refseq:XP_016883701.1|refseq:XP_016883702.1|refseq:XP_016883703.1|refseq:XP_016883704.1|refseq:XP_016883705.1|refseq:XP_016883706.1|refseq:XP_016883707.1|refseq:XP_016883978.1|refseq:XP_016883979.1|refseq:XP_016883980.1|refseq:XP_016883981.1|entrezgene/locuslink:875(identity)	-	crc64:8D3A0CB76F2E7C00	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:NyzC93xnBCb8DX/AH346lwg4u2A559292	rogid:f9eo0cPOHppVY7Nqejag3YyK18s9606	intact-crc:38845B024FAE8B5F|rigid:sHjkU2Xr5Rp+0zmlZ6aoAynaMus	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q02821	uniprotkb:P22234	intact:EBI-1797|uniprotkb:D6W0Z8|ensemblfungi:YNL189W	intact:EBI-712261|ensembl:ENSP00000264221|ensembl:ENSP00000421096|uniprotkb:E9PDH9|uniprotkb:Q68CQ5|intact:EBI-21352784	psi-mi:ima1_yeast(display_long)|uniprotkb:SRP1(gene name)|psi-mi:SRP1(display_short)|uniprotkb:KAP60(gene name synonym)|uniprotkb:YNL189W(locus name)|uniprotkb:N1606(orf name)|uniprotkb:Karyopherin subunit alpha(gene name synonym)|uniprotkb:Karyopherin-60(gene name synonym)|uniprotkb:Serine-rich RNA polymerase I suppressor protein(gene name synonym)	psi-mi:pur6_human(display_long)|uniprotkb:PAICS(gene name)|psi-mi:PAICS(display_short)|uniprotkb:ADE2(gene name synonym)|uniprotkb:AIRC(gene name synonym)|uniprotkb:PAIS(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11544909|imex:IM-24995-2380	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014210.1|sgd:S000005133|dip:DIP-728N|mint:Q02821|ensemblfungi:YNL189W(gene)|ensemblfungi:YNL189W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0031144"(proteasome localization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042564"(NLS-dependent protein nuclear import complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|rcsb pdb:1BK5|rcsb pdb:1BK6|rcsb pdb:1EE4|rcsb pdb:1EE5|rcsb pdb:1UN0|rcsb pdb:1WA5|rcsb pdb:2C1T|rcsb pdb:4PVZ|rcsb pdb:4XZR|rcsb pdb:5H2W|rcsb pdb:5H2X|rcsb pdb:5T94|sgd:YNL189W(identity)	ensembl:ENSG00000128050(gene)|ensembl:ENST00000264221(transcript)|ensembl:ENST00000512576(transcript)|go:"GO:0004639"(phosphoribosylaminoimidazolesuccinocarboxamide synthase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006189"('de novo' IMP biosynthetic process)|go:"GO:0009113"(purine nucleobase biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043727"(5-amino-4-imidazole carboxylate lyase activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000031("1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase")|interpro:IPR018236|interpro:IPR028923|interpro:IPR033626|mint:P22234|rcsb pdb:2H31|rcsb pdb:6YB8|go:"GO:0004638"(phosphoribosylaminoimidazole carboxylase activity)|rcsb pdb:6YB9|reactome:R-HSA-73817|refseq:NP_001072992.1|refseq:NP_001072993.1|refseq:NP_006443.1|entrezgene/locuslink:10606(identity)	-	crc64:8D3A0CB76F2E7C00	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:NyzC93xnBCb8DX/AH346lwg4u2A559292	rogid:aR4Xj14ZQrPiY8cldw5o9AvjkAo9606	intact-crc:4755037849CB56BB|rigid:XSq92qAfiIwgMiiBbsb5w5CSRFU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q15038	uniprotkb:Q02821	intact:EBI-724310|ensembl:ENSP00000394699|uniprotkb:E9PB45|uniprotkb:A8K254|uniprotkb:B4DDT5|uniprotkb:C9JA96|uniprotkb:C9JP84|uniprotkb:B4E1G3|uniprotkb:F8VU62	intact:EBI-1797|uniprotkb:D6W0Z8|ensemblfungi:YNL189W	psi-mi:dazp2_human(display_long)|uniprotkb:Deleted in azoospermia-associated protein 2(gene name synonym)|uniprotkb:DAZAP2(gene name)|psi-mi:DAZAP2(display_short)|uniprotkb:KIAA0058(gene name synonym)	psi-mi:ima1_yeast(display_long)|uniprotkb:SRP1(gene name)|psi-mi:SRP1(display_short)|uniprotkb:KAP60(gene name synonym)|uniprotkb:YNL189W(locus name)|uniprotkb:N1606(orf name)|uniprotkb:Karyopherin subunit alpha(gene name synonym)|uniprotkb:Karyopherin-60(gene name synonym)|uniprotkb:Serine-rich RNA polymerase I suppressor protein(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11544975|imex:IM-24995-2387	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000183283(gene)|ensembl:ENST00000412716(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0016607"(nuclear speck)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0050699"(WW domain binding)|interpro:IPR022730|mint:Q15038|refseq:NP_001129736.1|refseq:NP_055579.1|ensembl:ENSP00000394699|ensembl:ENST00000425012|ensembl:ENSP00000408251|ensembl:ENST00000439799|ensembl:ENSP00000398804|ensembl:ENST00000449723|ensembl:ENSP00000412812|ensembl:ENST00000549555|ensembl:ENSP00000448051|ensembl:ENST00000549732|ensembl:ENSP00000446554|refseq:NP_001129741.1|refseq:NP_001129739.1|refseq:NP_001129740.1|refseq:NP_001129738.1|entrezgene/locuslink:9802(identity)	refseq:NP_014210.1|sgd:S000005133|dip:DIP-728N|mint:Q02821|ensemblfungi:YNL189W(gene)|ensemblfungi:YNL189W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0031144"(proteasome localization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042564"(NLS-dependent protein nuclear import complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|rcsb pdb:1BK5|rcsb pdb:1BK6|rcsb pdb:1EE4|rcsb pdb:1EE5|rcsb pdb:1UN0|rcsb pdb:1WA5|rcsb pdb:2C1T|rcsb pdb:4PVZ|rcsb pdb:4XZR|rcsb pdb:5H2W|rcsb pdb:5H2X|rcsb pdb:5T94|sgd:YNL189W(identity)	-	-	crc64:8D3A0CB76F2E7C00	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:ASRqCZBG4q1U/y95PUSMKsgfm/g9606	rogid:NyzC93xnBCb8DX/AH346lwg4u2A559292	intact-crc:79B06AED7C616CC0|rigid:yCLVefhV7x77d29dFaxQHSx62kQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q02821	uniprotkb:Q13867	intact:EBI-1797|uniprotkb:D6W0Z8|ensemblfungi:YNL189W	intact:EBI-718504|uniprotkb:Q53F86|uniprotkb:Q9UER9|uniprotkb:B2R796|ensembl:ENSP00000261714	psi-mi:ima1_yeast(display_long)|uniprotkb:SRP1(gene name)|psi-mi:SRP1(display_short)|uniprotkb:KAP60(gene name synonym)|uniprotkb:YNL189W(locus name)|uniprotkb:N1606(orf name)|uniprotkb:Karyopherin subunit alpha(gene name synonym)|uniprotkb:Karyopherin-60(gene name synonym)|uniprotkb:Serine-rich RNA polymerase I suppressor protein(gene name synonym)	psi-mi:blmh_human(display_long)|uniprotkb:BLMH(gene name)|psi-mi:BLMH(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11544966|imex:IM-24995-2386	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014210.1|sgd:S000005133|dip:DIP-728N|mint:Q02821|ensemblfungi:YNL189W(gene)|ensemblfungi:YNL189W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0031144"(proteasome localization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042564"(NLS-dependent protein nuclear import complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|rcsb pdb:1BK5|rcsb pdb:1BK6|rcsb pdb:1EE4|rcsb pdb:1EE5|rcsb pdb:1UN0|rcsb pdb:1WA5|rcsb pdb:2C1T|rcsb pdb:4PVZ|rcsb pdb:4XZR|rcsb pdb:5H2W|rcsb pdb:5H2X|rcsb pdb:5T94|sgd:YNL189W(identity)	refseq:NP_000377.1|ensembl:ENSG00000108578(gene)|ensembl:ENST00000261714(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004177"(aminopeptidase activity)|go:"GO:0004180"(carboxypeptidase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006508"(proteolysis)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0009636"(response to toxic substance)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043418"(homocysteine catabolic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000169(Peptidase, cysteine peptidase active site)|interpro:IPR004134(Peptidase C1B, bleomycin hydrolase)|interpro:IPR038765|mint:Q13867|rcsb pdb:1CB5|rcsb pdb:2CB5|reactome:R-HSA-983168|entrezgene/locuslink:642(identity)	-	crc64:8D3A0CB76F2E7C00	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:NyzC93xnBCb8DX/AH346lwg4u2A559292	rogid:THDv63DC81eQzFvmyWs1rlCBMyk9606	intact-crc:3C77B264619316F8|rigid:mXEqsbkDTq9X7I09Sl2jwXhN0bE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q13557-8	uniprotkb:Q02821	intact:EBI-11534483|ensembl:ENSP00000296402|ensembl:ENSP00000369098	intact:EBI-1797|uniprotkb:D6W0Z8|ensemblfungi:YNL189W	psi-mi:q13557-8(display_long)|uniprotkb:CAMKD(gene name synonym)|uniprotkb:CAMK2D(gene name)|psi-mi:CAMK2D(display_short)	psi-mi:ima1_yeast(display_long)|uniprotkb:SRP1(gene name)|psi-mi:SRP1(display_short)|uniprotkb:KAP60(gene name synonym)|uniprotkb:YNL189W(locus name)|uniprotkb:N1606(orf name)|uniprotkb:Karyopherin subunit alpha(gene name synonym)|uniprotkb:Karyopherin-60(gene name synonym)|uniprotkb:Serine-rich RNA polymerase I suppressor protein(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11544957|imex:IM-24995-2385	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-351018(isoform-parent)|ensembl:ENSG00000145349(gene)|ensembl:ENST00000296402(transcript)|ensembl:ENST00000379773(transcript)|uniprotkb:Q13557-8(isoform-parent)|entrezgene/locuslink:817(identity)	refseq:NP_014210.1|sgd:S000005133|dip:DIP-728N|mint:Q02821|ensemblfungi:YNL189W(gene)|ensemblfungi:YNL189W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0031144"(proteasome localization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042564"(NLS-dependent protein nuclear import complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|rcsb pdb:1BK5|rcsb pdb:1BK6|rcsb pdb:1EE4|rcsb pdb:1EE5|rcsb pdb:1UN0|rcsb pdb:1WA5|rcsb pdb:2C1T|rcsb pdb:4PVZ|rcsb pdb:4XZR|rcsb pdb:5H2W|rcsb pdb:5H2X|rcsb pdb:5T94|sgd:YNL189W(identity)	-	-	crc64:8D3A0CB76F2E7C00	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:44T/I8JdalScCNE5Vp/H+PnfdFo9606	rogid:NyzC93xnBCb8DX/AH346lwg4u2A559292	intact-crc:437028C357E11A27|rigid:Vp8do7OhElgVpphFHYjWx5CkT18	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9NS73-5	uniprotkb:Q02821	intact:EBI-10182361|ensembl:ENSP00000324444	intact:EBI-1797|uniprotkb:D6W0Z8|ensemblfungi:YNL189W	psi-mi:q9ns73-5(display_long)|uniprotkb:MAPK upstream kinase-binding inhibitory protein(gene name synonym)|uniprotkb:BM-015(orf name)|uniprotkb:MBIP(gene name)|psi-mi:MBIP(display_short)	psi-mi:ima1_yeast(display_long)|uniprotkb:SRP1(gene name)|psi-mi:SRP1(display_short)|uniprotkb:KAP60(gene name synonym)|uniprotkb:YNL189W(locus name)|uniprotkb:N1606(orf name)|uniprotkb:Karyopherin subunit alpha(gene name synonym)|uniprotkb:Karyopherin-60(gene name synonym)|uniprotkb:Serine-rich RNA polymerase I suppressor protein(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11545020|imex:IM-24995-2392	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000151332(gene)|ensembl:ENST00000318473(transcript)|intact:EBI-741953(isoform-parent)|uniprotkb:Q9NS73-5(isoform-parent)|entrezgene/locuslink:51562(identity)	refseq:NP_014210.1|sgd:S000005133|dip:DIP-728N|mint:Q02821|ensemblfungi:YNL189W(gene)|ensemblfungi:YNL189W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0031144"(proteasome localization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042564"(NLS-dependent protein nuclear import complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|rcsb pdb:1BK5|rcsb pdb:1BK6|rcsb pdb:1EE4|rcsb pdb:1EE5|rcsb pdb:1UN0|rcsb pdb:1WA5|rcsb pdb:2C1T|rcsb pdb:4PVZ|rcsb pdb:4XZR|rcsb pdb:5H2W|rcsb pdb:5H2X|rcsb pdb:5T94|sgd:YNL189W(identity)	-	-	crc64:8D3A0CB76F2E7C00	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:JVmcJrT3SXRZwv9U285cNqnXWQE9606	rogid:NyzC93xnBCb8DX/AH346lwg4u2A559292	intact-crc:E2EAD4ED096975AD|rigid:keYNqWVWUF9B+O6/G0K2ascnBwA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9NS73	uniprotkb:Q02821	intact:EBI-741953|uniprotkb:Q86TZ2|uniprotkb:Q96AS5|uniprotkb:Q9BS93|uniprotkb:Q9NZE1|ensembl:ENSP00000399718	intact:EBI-1797|uniprotkb:D6W0Z8|ensemblfungi:YNL189W	psi-mi:mbip1_human(display_long)|uniprotkb:MAPK upstream kinase-binding inhibitory protein(gene name synonym)|uniprotkb:MBIP(gene name)|psi-mi:MBIP(display_short)|uniprotkb:BM-015(orf name)	psi-mi:ima1_yeast(display_long)|uniprotkb:SRP1(gene name)|psi-mi:SRP1(display_short)|uniprotkb:KAP60(gene name synonym)|uniprotkb:YNL189W(locus name)|uniprotkb:N1606(orf name)|uniprotkb:Karyopherin subunit alpha(gene name synonym)|uniprotkb:Karyopherin-60(gene name synonym)|uniprotkb:Serine-rich RNA polymerase I suppressor protein(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11545011|imex:IM-24995-2391	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001138363.1|refseq:NP_057670.2|ensembl:ENSG00000151332(gene)|ensembl:ENST00000416007(transcript)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0042802"(identical protein binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0046330"(positive regulation of JNK cascade)|interpro:IPR026062|mint:Q9NS73|reactome:R-HSA-3214847|go:"GO:0005654"(nucleoplasm)|refseq:NP_001295039.1|entrezgene/locuslink:51562(identity)	refseq:NP_014210.1|sgd:S000005133|dip:DIP-728N|mint:Q02821|ensemblfungi:YNL189W(gene)|ensemblfungi:YNL189W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0031144"(proteasome localization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042564"(NLS-dependent protein nuclear import complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|rcsb pdb:1BK5|rcsb pdb:1BK6|rcsb pdb:1EE4|rcsb pdb:1EE5|rcsb pdb:1UN0|rcsb pdb:1WA5|rcsb pdb:2C1T|rcsb pdb:4PVZ|rcsb pdb:4XZR|rcsb pdb:5H2W|rcsb pdb:5H2X|rcsb pdb:5T94|sgd:YNL189W(identity)	-	-	crc64:8D3A0CB76F2E7C00	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:PjaEuab6wwOyGImpNYFZfQ+TUvU9606	rogid:NyzC93xnBCb8DX/AH346lwg4u2A559292	intact-crc:0C5239C20DF54BC5|rigid:QDAkj1JjcjC1M6fXPGwGjxHqPWE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9HAN9	uniprotkb:Q02821	intact:EBI-3917542|uniprotkb:Q8TAE9|uniprotkb:Q9H6B6|uniprotkb:Q9H247|uniprotkb:B1AN63|ensembl:ENSP00000366410|ensembl:ENSP00000435134	intact:EBI-1797|uniprotkb:D6W0Z8|ensemblfungi:YNL189W	psi-mi:nmna1_human(display_long)|uniprotkb:NMNAT1(gene name)|psi-mi:NMNAT1(display_short)|uniprotkb:NMNAT(gene name synonym)|uniprotkb:Nicotinate-nucleotide adenylyltransferase 1(gene name synonym)|uniprotkb:Nicotinamide-nucleotide adenylyltransferase 1(gene name synonym)	psi-mi:ima1_yeast(display_long)|uniprotkb:SRP1(gene name)|psi-mi:SRP1(display_short)|uniprotkb:KAP60(gene name synonym)|uniprotkb:YNL189W(locus name)|uniprotkb:N1606(orf name)|uniprotkb:Karyopherin subunit alpha(gene name synonym)|uniprotkb:Karyopherin-60(gene name synonym)|uniprotkb:Serine-rich RNA polymerase I suppressor protein(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11545002|imex:IM-24995-2390	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001284707.1|refseq:NP_073624.2|ensembl:ENSG00000173614(gene)|ensembl:ENST00000377205(transcript)|ensembl:ENST00000462686(transcript)|go:"GO:0000309"(nicotinamide-nucleotide adenylyltransferase activity)|go:"GO:0004515"(nicotinate-nucleotide adenylyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0009165"(nucleotide biosynthetic process)|go:"GO:0009435"(NAD biosynthetic process)|go:"GO:0009611"(response to wounding)|go:"GO:0016604"(nuclear body)|go:"GO:0042802"(identical protein binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:1902511"(negative regulation of apoptotic DNA fragmentation)|go:"GO:1990966"(ATP generation from poly-ADP-D-ribose)|interpro:IPR004821(Cytidyltransferase-related)|interpro:IPR005248(Probable nicotinate-nucleotide adenylyltransferase)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|mint:Q9HAN9|rcsb pdb:1GZU|rcsb pdb:1KKU|rcsb pdb:1KQN|rcsb pdb:1KQO|rcsb pdb:1KR2|reactome:R-HSA-196807|refseq:XP_016857596.1|dip:DIP-60881N|entrezgene/locuslink:64802(identity)	refseq:NP_014210.1|sgd:S000005133|dip:DIP-728N|mint:Q02821|ensemblfungi:YNL189W(gene)|ensemblfungi:YNL189W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0031144"(proteasome localization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042564"(NLS-dependent protein nuclear import complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|rcsb pdb:1BK5|rcsb pdb:1BK6|rcsb pdb:1EE4|rcsb pdb:1EE5|rcsb pdb:1UN0|rcsb pdb:1WA5|rcsb pdb:2C1T|rcsb pdb:4PVZ|rcsb pdb:4XZR|rcsb pdb:5H2W|rcsb pdb:5H2X|rcsb pdb:5T94|sgd:YNL189W(identity)	-	-	crc64:8D3A0CB76F2E7C00	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:KwV9lz04z3ptlVpKu3b534Yekpc9606	rogid:NyzC93xnBCb8DX/AH346lwg4u2A559292	intact-crc:08C1252A325D83F0|rigid:hiVoR93U7NxzHo9Ck1njCpBKh28	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8WVF5	uniprotkb:Q02821	intact:EBI-741463|ensembl:ENSP00000368402|uniprotkb:Q5W0P9	intact:EBI-1797|uniprotkb:D6W0Z8|ensemblfungi:YNL189W	psi-mi:kctd4_human(display_long)|uniprotkb:KCTD4(gene name)|psi-mi:KCTD4(display_short)	psi-mi:ima1_yeast(display_long)|uniprotkb:SRP1(gene name)|psi-mi:SRP1(display_short)|uniprotkb:KAP60(gene name synonym)|uniprotkb:YNL189W(locus name)|uniprotkb:N1606(orf name)|uniprotkb:Karyopherin subunit alpha(gene name synonym)|uniprotkb:Karyopherin-60(gene name synonym)|uniprotkb:Serine-rich RNA polymerase I suppressor protein(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11544993|imex:IM-24995-2389	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000180332(gene)|ensembl:ENST00000379108(transcript)|go:"GO:0051260"(protein homooligomerization)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR003131(Potassium channel, voltage dependent, Kv,  tetramerisation)|interpro:IPR011333(BTB/POZ fold)|refseq:NP_940686.2|entrezgene/locuslink:386618(identity)	refseq:NP_014210.1|sgd:S000005133|dip:DIP-728N|mint:Q02821|ensemblfungi:YNL189W(gene)|ensemblfungi:YNL189W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0031144"(proteasome localization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042564"(NLS-dependent protein nuclear import complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|rcsb pdb:1BK5|rcsb pdb:1BK6|rcsb pdb:1EE4|rcsb pdb:1EE5|rcsb pdb:1UN0|rcsb pdb:1WA5|rcsb pdb:2C1T|rcsb pdb:4PVZ|rcsb pdb:4XZR|rcsb pdb:5H2W|rcsb pdb:5H2X|rcsb pdb:5T94|sgd:YNL189W(identity)	-	-	crc64:8D3A0CB76F2E7C00	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:03cd1lqmT8fReXzYqjrKSWUdqY89606	rogid:NyzC93xnBCb8DX/AH346lwg4u2A559292	intact-crc:892607552F26AB8F|rigid:6KdU4mjtwdu6qyVglZVNc05/CUs	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q02821	uniprotkb:Q15041	intact:EBI-1797|uniprotkb:D6W0Z8|ensemblfungi:YNL189W	intact:EBI-714543|ensembl:ENSP00000306788|uniprotkb:B7Z6S5|uniprotkb:B7Z791|uniprotkb:F5GXP4	psi-mi:ima1_yeast(display_long)|uniprotkb:SRP1(gene name)|psi-mi:SRP1(display_short)|uniprotkb:KAP60(gene name synonym)|uniprotkb:YNL189W(locus name)|uniprotkb:N1606(orf name)|uniprotkb:Karyopherin subunit alpha(gene name synonym)|uniprotkb:Karyopherin-60(gene name synonym)|uniprotkb:Serine-rich RNA polymerase I suppressor protein(gene name synonym)	psi-mi:ar6p1_human(display_long)|uniprotkb:ARL6IP(gene name synonym)|uniprotkb:ARL6IP1(gene name)|psi-mi:ARL6IP1(display_short)|uniprotkb:KIAA0069(gene name synonym)|uniprotkb:ARMER(gene name synonym)|uniprotkb:Apoptotic regulator in the membrane of the endoplasmic reticulum(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11544984|imex:IM-24995-2388	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014210.1|sgd:S000005133|dip:DIP-728N|mint:Q02821|ensemblfungi:YNL189W(gene)|ensemblfungi:YNL189W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0031144"(proteasome localization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042564"(NLS-dependent protein nuclear import complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|rcsb pdb:1BK5|rcsb pdb:1BK6|rcsb pdb:1EE4|rcsb pdb:1EE5|rcsb pdb:1UN0|rcsb pdb:1WA5|rcsb pdb:2C1T|rcsb pdb:4PVZ|rcsb pdb:4XZR|rcsb pdb:5H2W|rcsb pdb:5H2X|rcsb pdb:5T94|sgd:YNL189W(identity)	refseq:NP_055976.1|ensembl:ENSG00000170540(gene)|ensembl:ENST00000304414(transcript)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006613"(cotranslational protein targeting to membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0071787"(endoplasmic reticulum tubular network formation)|go:"GO:1903371"(regulation of endoplasmic reticulum tubular network organization)|go:"GO:1990809"(endoplasmic reticulum tubular network membrane organization)|interpro:IPR033301|mint:Q15041|go:"GO:0002038"(positive regulation of L-glutamate import across plasma membrane)|refseq:NP_001300787.1|entrezgene/locuslink:23204(identity)	-	crc64:8D3A0CB76F2E7C00	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:NyzC93xnBCb8DX/AH346lwg4u2A559292	rogid:3fjkoyvUx25po7xsPcXgpjEeLJg9606	intact-crc:E84D087703647DAF|rigid:IgRYyzm7Dnd+YxZ8YMSEE+zMZNs	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O95751	uniprotkb:Q02831	intact:EBI-740738|ensembl:ENSP00000359557|uniprotkb:Q6IAR6	intact:EBI-31828|uniprotkb:D6W3T9|ensemblfungi:YPL077C	psi-mi:ldoc1_human(display_long)|uniprotkb:Leucine zipper protein down-regulated in cancer cells(gene name synonym)|uniprotkb:LDOC1(gene name)|psi-mi:LDOC1(display_short)|uniprotkb:BCUR1(gene name synonym)	psi-mi:yp077_yeast(display_long)|uniprotkb:YPL077C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11545060|imex:IM-24995-2396	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_036449.1|ensembl:ENSG00000182195(gene)|ensembl:ENST00000370526(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071225"(cellular response to muramyl dipeptide)|interpro:IPR032549|interpro:IPR032567|entrezgene/locuslink:23641(identity)	sgd:S000005998|refseq:NP_015248.1|dip:DIP-4022N|ensemblfungi:YPL077C(gene)|ensemblfungi:YPL077C_mRNA(transcript)|sgd:YPL077C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Ediu0oNiZ/+YVY8l3fNdgP5A+v09606	rogid:yqOn4GWKNmFZ7UvGmyBEpgoyKlA559292	intact-crc:114B7DE523102F5A|rigid:fHBBJNu1VoIgDlWXQtH3kp28p4c	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q02831	uniprotkb:Q7Z6G3-2	intact:EBI-31828|uniprotkb:D6W3T9|ensemblfungi:YPL077C	intact:EBI-10172876|ensembl:ENSP00000457354|intact:EBI-14062040	psi-mi:yp077_yeast(display_long)|uniprotkb:YPL077C(locus name)	psi-mi:q7z6g3-2(display_long)|uniprotkb:EFCBP2(gene name synonym)|uniprotkb:Neuronal calcium-binding protein 2(gene name synonym)|uniprotkb:Synaptotagmin-interacting protein 2(gene name synonym)|uniprotkb:NECAB2(gene name)|psi-mi:NECAB2(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11545049|imex:IM-24995-2395	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005998|refseq:NP_015248.1|dip:DIP-4022N|ensemblfungi:YPL077C(gene)|ensemblfungi:YPL077C_mRNA(transcript)|sgd:YPL077C(identity)	ensembl:ENSG00000103154(gene)|ensembl:ENST00000565691(transcript)|uniprotkb:Q7Z6G3-2(isoform-parent)|intact:EBI-950070(isoform-parent)|entrezgene/locuslink:54550(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:yqOn4GWKNmFZ7UvGmyBEpgoyKlA559292	rogid:4S7oIx6h+mKzV3EPxqcfMNqaNko9606	intact-crc:EFDA71D699AD0176|rigid:NS1rCXHrw1I2d8hIkI/N6uIQDic	false	-	sufficient binding region:65-303	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q02831	uniprotkb:Q08379	intact:EBI-31828|uniprotkb:D6W3T9|ensemblfungi:YPL077C	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	psi-mi:yp077_yeast(display_long)|uniprotkb:YPL077C(locus name)	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11545038|imex:IM-24995-2394	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005998|refseq:NP_015248.1|dip:DIP-4022N|ensemblfungi:YPL077C(gene)|ensemblfungi:YPL077C_mRNA(transcript)|sgd:YPL077C(identity)	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N|entrezgene/locuslink:2801(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2017/05/26	rogid:yqOn4GWKNmFZ7UvGmyBEpgoyKlA559292	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	intact-crc:374521617362C7CA|rigid:MRpEjW2Eb4yYRpTVVIPB+VFwef8	false	-	sufficient binding region:383-1002	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9NVV9	uniprotkb:Q02821	intact:EBI-741515|uniprotkb:Q53FQ1|uniprotkb:Q6IA99|ensembl:ENSP00000254250|uniprotkb:A6NCB6|uniprotkb:D3DSY5|uniprotkb:H9KV49	intact:EBI-1797|uniprotkb:D6W0Z8|ensemblfungi:YNL189W	psi-mi:thap1_human(display_long)|uniprotkb:THAP1(gene name)|psi-mi:THAP1(display_short)	psi-mi:ima1_yeast(display_long)|uniprotkb:SRP1(gene name)|psi-mi:SRP1(display_short)|uniprotkb:KAP60(gene name synonym)|uniprotkb:YNL189W(locus name)|uniprotkb:N1606(orf name)|uniprotkb:Karyopherin subunit alpha(gene name synonym)|uniprotkb:Karyopherin-60(gene name synonym)|uniprotkb:Serine-rich RNA polymerase I suppressor protein(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11545029|imex:IM-24995-2393	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060575.1|ensembl:ENSG00000131931(gene)|ensembl:ENST00000254250(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001650"(fibrillar center)|go:"GO:0001935"(endothelial cell proliferation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007049"(cell cycle)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016605"(PML body)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR006612(Zinc finger, C2CH-type)|interpro:IPR026516|interpro:IPR038441|mint:Q9NVV9|rcsb pdb:2JTG|rcsb pdb:2KO0|rcsb pdb:2L1G|refseq:NP_945354.1|entrezgene/locuslink:55145(identity)	refseq:NP_014210.1|sgd:S000005133|dip:DIP-728N|mint:Q02821|ensemblfungi:YNL189W(gene)|ensemblfungi:YNL189W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0031144"(proteasome localization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042564"(NLS-dependent protein nuclear import complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|rcsb pdb:1BK5|rcsb pdb:1BK6|rcsb pdb:1EE4|rcsb pdb:1EE5|rcsb pdb:1UN0|rcsb pdb:1WA5|rcsb pdb:2C1T|rcsb pdb:4PVZ|rcsb pdb:4XZR|rcsb pdb:5H2W|rcsb pdb:5H2X|rcsb pdb:5T94|sgd:YNL189W(identity)	-	-	crc64:8D3A0CB76F2E7C00	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:/KO90pu5tBnIVq9SMx1JYPXFCEQ9606	rogid:NyzC93xnBCb8DX/AH346lwg4u2A559292	intact-crc:88CC90EBD3EB6756|rigid:x/UGKue0dWbjDEhVKK+hw+DNx6Q	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q02831	uniprotkb:Q8IYF3-3	intact:EBI-31828|uniprotkb:D6W3T9|ensemblfungi:YPL077C	intact:EBI-11523345|ensembl:ENSP00000363453	psi-mi:yp077_yeast(display_long)|uniprotkb:YPL077C(locus name)	psi-mi:q8iyf3-3(display_long)|uniprotkb:TEX11(gene name)|psi-mi:TEX11(display_short)|uniprotkb:Protein ZIP4 homolog(gene name synonym)|uniprotkb:ZIP4(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11545096|imex:IM-24995-2400	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005998|refseq:NP_015248.1|dip:DIP-4022N|ensemblfungi:YPL077C(gene)|ensemblfungi:YPL077C_mRNA(transcript)|sgd:YPL077C(identity)	ensembl:ENSG00000120498(gene)|ensembl:ENST00000374333(transcript)|intact:EBI-742397(isoform-parent)|uniprotkb:Q8IYF3-3(isoform-parent)|entrezgene/locuslink:56159(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:yqOn4GWKNmFZ7UvGmyBEpgoyKlA559292	rogid:PUAMFmnm5ZV2rnJ1rhm9ZeRCixg9606	intact-crc:C3FEBB4B2C7152FF|rigid:yEHXFav+2oeLW097llC8xw/biz0	false	-	sufficient binding region:9-925	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q02831	uniprotkb:P37198	intact:EBI-31828|uniprotkb:D6W3T9|ensemblfungi:YPL077C	intact:EBI-347978|intact:EBI-28983799|ensembl:ENSP00000305503|ensembl:ENSP00000407331|ensembl:ENSP00000471191|ensembl:ENSP00000473192|uniprotkb:Q6GTM2|uniprotkb:Q503A4|uniprotkb:Q96C43|uniprotkb:Q9NSL1|uniprotkb:B3KWU5	psi-mi:yp077_yeast(display_long)|uniprotkb:YPL077C(locus name)	psi-mi:nup62_human(display_long)|uniprotkb:NUP62(gene name)|psi-mi:NUP62(display_short)|uniprotkb:62 kDa nucleoporin(gene name synonym)|uniprotkb:Nucleoporin Nup62(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11545087|imex:IM-24995-2399	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005998|refseq:NP_015248.1|dip:DIP-4022N|ensemblfungi:YPL077C(gene)|ensemblfungi:YPL077C_mRNA(transcript)|sgd:YPL077C(identity)	refseq:NP_714941.1|ensembl:ENSG00000213024(gene)|ensembl:ENST00000352066(transcript)|ensembl:ENST00000422090(transcript)|ensembl:ENST00000596217(transcript)|ensembl:ENST00000597029(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005642"(annulate lamellae)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007100"(mitotic centrosome separation)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007569"(cell aging)|go:"GO:0008219"(cell death)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0003682"(chromatin binding)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0019894"(kinesin binding)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042306"(regulation of protein import into nucleus)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043069"(negative regulation of programmed cell death)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045742"(positive regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046578"(regulation of Ras protein signal transduction)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0046601"(positive regulation of centriole replication)|go:"GO:0051028"(mRNA transport)|go:"GO:0051425"(PTB domain binding)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0072686"(mitotic spindle)|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|go:"GO:0090543"(Flemming body)|go:"GO:0098534"(centriole assembly)|go:"GO:1903438"(positive regulation of mitotic cytokinetic process)|go:"GO:1904781"(positive regulation of protein localization to centrosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR007758(Nucleoporin, Nsp1-like, C-terminal)|interpro:IPR026010|interpro:IPR033072|mint:P37198|rcsb pdb:2H4D|rcsb pdb:5IJN|rcsb pdb:5IJO|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|refseq:NP_714940.1|refseq:NP_001180286.1|refseq:NP_036478.2|refseq:NP_057637.2|ensembl:ENSP00000305503|ensembl:ENSP00000407331|ensembl:ENSP00000471191|ensembl:ENSP00000473192|dip:DIP-29749N|entrezgene/locuslink:23636(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:yqOn4GWKNmFZ7UvGmyBEpgoyKlA559292	rogid:v7mvKvTtVEnLMwcpUZIcdAzge009606	intact-crc:DE31A1306E69F386|rigid:Iu3MYsKsSKmQS3zrsuXCmq0qeY4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P19012	uniprotkb:Q02831	intact:EBI-739566|uniprotkb:Q53XV8|uniprotkb:Q9BUG4|uniprotkb:B3KQY1|uniprotkb:B3KRA2|uniprotkb:E0CX14|ensembl:ENSP00000254043|ensembl:ENSP00000377546	intact:EBI-31828|uniprotkb:D6W3T9|ensemblfungi:YPL077C	psi-mi:k1c15_human(display_long)|uniprotkb:KRT15(gene name)|psi-mi:KRT15(display_short)|uniprotkb:KRTB(gene name synonym)|uniprotkb:Cytokeratin-15(gene name synonym)|uniprotkb:Keratin-15(gene name synonym)	psi-mi:yp077_yeast(display_long)|uniprotkb:YPL077C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11545078|imex:IM-24995-2398	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002266.2|ensembl:ENSG00000171346(gene)|ensembl:ENST00000254043(transcript)|ensembl:ENST00000393976(transcript)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0008544"(epidermis development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097110"(scaffold protein binding)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR039008|mint:P19012|reactome:R-HSA-6805567|reactome:R-HSA-6809371|entrezgene/locuslink:3866(identity)	sgd:S000005998|refseq:NP_015248.1|dip:DIP-4022N|ensemblfungi:YPL077C(gene)|ensemblfungi:YPL077C_mRNA(transcript)|sgd:YPL077C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:WrZQBYQvrWcfrR5ojWXrXp6spPE9606	rogid:yqOn4GWKNmFZ7UvGmyBEpgoyKlA559292	intact-crc:DF828653696995A2|rigid:P9Ll3LXUd9uJ+1g3ix//cxWtTZM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P14373	uniprotkb:Q02831	intact:EBI-719493|uniprotkb:A2BE15|uniprotkb:Q5RJA8|uniprotkb:Q5ST26|uniprotkb:Q6LA73|uniprotkb:Q6NXR9|uniprotkb:Q9BZY6|uniprotkb:Q9UJL3|ensembl:ENSP00000383555|ensembl:ENSP00000392787|ensembl:ENSP00000405229|ensembl:ENSP00000414793|ensembl:ENSP00000366404	intact:EBI-31828|uniprotkb:D6W3T9|ensemblfungi:YPL077C	psi-mi:tri27_human(display_long)|uniprotkb:TRIM27(gene name)|psi-mi:TRIM27(display_short)|uniprotkb:RNF76(gene name synonym)|uniprotkb:RFP(gene name synonym)|uniprotkb:Ret finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 27(gene name synonym)|uniprotkb:RING finger protein 76(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM27(gene name synonym)	psi-mi:yp077_yeast(display_long)|uniprotkb:YPL077C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11545069|imex:IM-24995-2397	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006501.1|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0090281"(negative regulation of calcium ion import)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR020457|interpro:IPR035791|interpro:IPR043136|mint:P14373|reactome:R-HSA-3232142|reactome:R-HSA-9635465|reactome:R-HSA-8948751|ensembl:ENSG00000204713(gene)|ensembl:ENSG00000215641(gene)|ensembl:ENSG00000229006(gene)|ensembl:ENSG00000234495(gene)|ensembl:ENSG00000237071(gene)|ensembl:ENST00000377199(transcript)|ensembl:ENST00000400720(transcript)|ensembl:ENST00000431123(transcript)|ensembl:ENST00000435528(transcript)|ensembl:ENST00000437160(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001650"(fibrillar center)|go:"GO:0002820"(negative regulation of adaptive immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|entrezgene/locuslink:5987(identity)	sgd:S000005998|refseq:NP_015248.1|dip:DIP-4022N|ensemblfungi:YPL077C(gene)|ensemblfungi:YPL077C_mRNA(transcript)|sgd:YPL077C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:dsfH5OUghD8KSaTz1SFw9OYVTK49606	rogid:yqOn4GWKNmFZ7UvGmyBEpgoyKlA559292	intact-crc:AE486D1436F696CE|rigid:Q8eGCfFM3ftJdYSF/cdD+C4spWQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q02831	uniprotkb:Q9C0F1	intact:EBI-31828|uniprotkb:D6W3T9|ensemblfungi:YPL077C	intact:EBI-744115|uniprotkb:A8K8W9|uniprotkb:B3KT53|uniprotkb:Q8IXZ4|uniprotkb:A8MW11|uniprotkb:D3DP42|ensembl:ENSP00000296519|ensembl:ENSP00000380009|ensembl:ENSP00000423153	psi-mi:yp077_yeast(display_long)|uniprotkb:YPL077C(locus name)	psi-mi:cep44_human(display_long)|uniprotkb:HBV PreS1-transactivated protein 3(gene name synonym)|uniprotkb:CEP44(gene name)|psi-mi:CEP44(display_short)|uniprotkb:KIAA1712(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11545125|imex:IM-24995-2403	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005998|refseq:NP_015248.1|dip:DIP-4022N|ensemblfungi:YPL077C(gene)|ensemblfungi:YPL077C_mRNA(transcript)|sgd:YPL077C(identity)	refseq:NP_001035247.1|refseq:NP_001138786.1|refseq:XP_011530587.1|refseq:XP_011530588.1|refseq:XP_011530589.1|refseq:XP_016864143.1|refseq:XP_016864144.1|ensembl:ENSG00000164118(gene)|ensembl:ENST00000296519(transcript)|ensembl:ENST00000396791(transcript)|ensembl:ENST00000503780(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007099"(centriole replication)|go:"GO:0008017"(microtubule binding)|go:"GO:0010457"(centriole-centriole cohesion)|go:"GO:0030496"(midbody)|interpro:IPR029157|interpro:IPR033603|mint:Q9C0F1|entrezgene/locuslink:80817(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:yqOn4GWKNmFZ7UvGmyBEpgoyKlA559292	rogid:gDTC64oDhudGdsssC7v+suIHZkA9606	intact-crc:F84DC0986FDBE50B|rigid:50Q2gyGzBzcnEF7jVh1IkGQULws	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q02831	uniprotkb:Q9BW62	intact:EBI-31828|uniprotkb:D6W3T9|ensemblfungi:YPL077C	intact:EBI-743591|uniprotkb:A8K5X4|ensembl:ENSP00000369989|ensembl:ENSP00000369991	psi-mi:yp077_yeast(display_long)|uniprotkb:YPL077C(locus name)	psi-mi:katl1_human(display_long)|uniprotkb:p60 katanin-like 1(gene name synonym)|uniprotkb:KATNAL1(gene name)|psi-mi:KATNAL1(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11545116|imex:IM-24995-2402	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005998|refseq:NP_015248.1|dip:DIP-4022N|ensemblfungi:YPL077C(gene)|ensemblfungi:YPL077C_mRNA(transcript)|sgd:YPL077C(identity)	refseq:NP_001014402.1|refseq:NP_115492.1|refseq:XP_005266631.1|ensembl:ENSG00000102781(gene)|ensembl:ENST00000380615(transcript)|ensembl:ENST00000380617(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005874"(microtubule)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008017"(microtubule binding)|go:"GO:0008568"(microtubule-severing ATPase activity)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016853"(isomerase activity)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0042802"(identical protein binding)|go:"GO:0051013"(microtubule severing)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR027417|interpro:IPR028594|interpro:IPR028596|interpro:IPR041569|rcsb pdb:6B5C|entrezgene/locuslink:84056(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:yqOn4GWKNmFZ7UvGmyBEpgoyKlA559292	rogid:Usi4KXsvZnNfMOGuWVSz4mfrTaE9606	intact-crc:1350A54978CE8111|rigid:2q/MAHUgYzbqg3hSIr9fvteYX7Q	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8N6Y0	uniprotkb:Q02831	intact:EBI-739895|uniprotkb:Q8NBX7|uniprotkb:Q96KH3|uniprotkb:Q9BYI8|uniprotkb:A8K7L6|uniprotkb:B2RCR9|ensembl:ENSP00000252597	intact:EBI-31828|uniprotkb:D6W3T9|ensemblfungi:YPL077C	psi-mi:usbp1_human(display_long)|uniprotkb:USHBP1(gene name)|psi-mi:USHBP1(display_short)|uniprotkb:MCC-2(gene name synonym)|uniprotkb:AIE-75-binding protein(gene name synonym)|uniprotkb:AIEBP(gene name synonym)|uniprotkb:MCC2(gene name synonym)|uniprotkb:Mutated in colon cancer protein 2(gene name synonym)	psi-mi:yp077_yeast(display_long)|uniprotkb:YPL077C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11545107|imex:IM-24995-2401	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001284632.1|refseq:NP_114147.2|refseq:NP_001308346.1|ensembl:ENSG00000130307(gene)|ensembl:ENST00000252597(transcript)|go:"GO:0030165"(PDZ domain binding)|interpro:IPR019536|interpro:IPR040171|entrezgene/locuslink:83878(identity)	sgd:S000005998|refseq:NP_015248.1|dip:DIP-4022N|ensemblfungi:YPL077C(gene)|ensemblfungi:YPL077C_mRNA(transcript)|sgd:YPL077C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:vY1qx73Ju/z7WDu6k1kd10ZDVRo9606	rogid:yqOn4GWKNmFZ7UvGmyBEpgoyKlA559292	intact-crc:5F5D3E74C03004E2|rigid:A6DAO/TQOlWtb+Y+m+iQwuLfKpM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q03020	uniprotkb:P12268	intact:EBI-29901|uniprotkb:D6W3N2|ensemblfungi:YPL135W	intact:EBI-353389|uniprotkb:Q6LEF3|ensembl:ENSP00000321584	psi-mi:isu1_yeast(display_long)|uniprotkb:YPL135W(locus name)|uniprotkb:Iron sulfur cluster scaffold protein 1(gene name synonym)|uniprotkb:ISU1(gene name)|psi-mi:ISU1(display_short)|uniprotkb:NUA1(gene name synonym)	psi-mi:imdh2_human(display_long)|uniprotkb:IMPDH2(gene name)|psi-mi:IMPDH2(display_short)|uniprotkb:IMPD2(gene name synonym)|uniprotkb:Inosine-5'-monophosphate dehydrogenase type II(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11545163|imex:IM-24995-2407	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015190.1|sgd:S000006056|dip:DIP-6556N|mint:Q03020|ensemblfungi:YPL135W(gene)|ensemblfungi:YPL135W_mRNA(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005506"(iron ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR002871(NIF system FeS cluster assembly, NifU, N-terminal)|interpro:IPR011339(ISC system FeS cluster assembly, IscU scaffold)|rcsb pdb:5T0V|rcsb pdb:5TRE|reactome:R-SCE-1362409|sgd:YPL135W(identity)	refseq:NP_000875.2|ensembl:ENSG00000178035(gene)|ensembl:ENST00000326739(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003938"(IMP dehydrogenase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006177"(GMP biosynthetic process)|go:"GO:0006183"(GTP biosynthetic process)|go:"GO:0007623"(circadian rhythm)|go:"GO:0016020"(membrane)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042802"(identical protein binding)|go:"GO:0046651"(lymphocyte proliferation)|go:"GO:0046872"(metal ion binding)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR001093(IMP dehydrogenase/GMP reductase)|interpro:IPR005990(IMP dehydrogenase)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR015875(IMP dehydrogenase / GMP reductase, conserved site)|mint:P12268|rcsb pdb:1B3O|rcsb pdb:1NF7|rcsb pdb:1NFB|rcsb pdb:6I0M|rcsb pdb:6I0O|rcsb pdb:6U8E|rcsb pdb:6U8N|rcsb pdb:6U8R|rcsb pdb:6U8S|rcsb pdb:6U9O|rcsb pdb:6UA2|rcsb pdb:6UA4|rcsb pdb:6UA5|rcsb pdb:6UAJ|rcsb pdb:6UC2|rcsb pdb:6UDO|rcsb pdb:6UDP|rcsb pdb:6UDQ|reactome:R-HSA-6798695|reactome:R-HSA-73817|reactome:R-HSA-9679191|entrezgene/locuslink:3615(identity)	-	crc64:E240845A27D2E9EE	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:zpPseOgZoK3cF+mCetzw05ct9Kc559292	rogid:qGPwBxhEgtYik3OetHZbpyktoLE9606	intact-crc:3E60E8D974B18DDC|rigid:UUS0JBOozVlfgyupMRQItfMqcVw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q02939	uniprotkb:E9PFK9	intact:EBI-2345544|uniprotkb:D6W3P5|uniprotkb:P87331|ensemblfungi:YPL122C	intact:EBI-11523104|ensembl:ENSP00000403429	psi-mi:tfb2_yeast(display_long)|uniprotkb:RNA polymerase II transcription factor B subunit 2(gene name synonym)|uniprotkb:YPL122C(locus name)|uniprotkb:TFB2(gene name)|psi-mi:TFB2(display_short)|uniprotkb:RNA polymerase II transcription factor B p52 subunit(gene name synonym)|uniprotkb:RNA polymerase II transcription factor B 52 kDa subunit(gene name synonym)	psi-mi:e9pfk9_human(display_long)|uniprotkb:RABGEF1(gene name)|psi-mi:RABGEF1(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11545152|imex:IM-24995-2406	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015203.1|sgd:S000006043|dip:DIP-5783N|mint:Q02939|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-5696395|reactome:R-SCE-674695|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-72086|reactome:R-SCE-73772|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075|ensemblfungi:YPL122C(gene)|ensemblfungi:YPL122C_mRNA(transcript)|go:"GO:0000112"(nucleotide-excision repair factor 3 complex)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR004598(Transcription factor Tfb2)|interpro:IPR040662|rcsb pdb:3DGP|rcsb pdb:3DOM|rcsb pdb:5FMF|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:5SVA|rcsb pdb:6GYM|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O4K|rcsb pdb:7O4L|rcsb pdb:7O72|rcsb pdb:7O73|sgd:YPL122C(identity)	ensembl:ENSG00000154710(gene)|ensembl:ENST00000439720(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|interpro:IPR002653(Zinc finger, A20-type)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR037191|interpro:IPR041545|entrezgene/locuslink:27342(identity)	-	crc64:9E440B566396A95A	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:TJC5kOBM7mOJLttEEiSqXvlVyXc559292	rogid:JDHW8cuCB2z39j6a+LlkARnLfYo9606	intact-crc:A567049194F3086E|rigid:Q8lrt3YrZkk3lWQRn1kFPM2jTyE	false	-	sufficient binding region:14-504	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q02872	uniprotkb:Q9NRF8	intact:EBI-38045|uniprotkb:D6W3Q9|ensemblfungi:YPL108W	intact:EBI-740874|ensembl:ENSP00000352222|ensembl:ENSP00000369590|ensembl:ENSP00000401264|uniprotkb:Q9BRI0|uniprotkb:Q9H809|uniprotkb:Q9H8K9|uniprotkb:B3KWM2	psi-mi:yp108_yeast(display_long)|uniprotkb:YPL108W(locus name)	psi-mi:pyrg2_human(display_long)|uniprotkb:UTP--ammonia ligase 2(gene name synonym)|uniprotkb:CTP synthetase 2(gene name synonym)|uniprotkb:CTPS2(gene name)|psi-mi:CTPS2(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11545143|imex:IM-24995-2405	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000006029|refseq:NP_015217.1|dip:DIP-5256N|ensemblfungi:YPL108W(gene)|ensemblfungi:YPL108W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|sgd:YPL108W(identity)	ensembl:ENSG00000047230(gene)|refseq:NP_001137474.1|refseq:NP_062831.3|refseq:NP_787055.1|ensembl:ENST00000359276(transcript)|ensembl:ENST00000380241(transcript)|ensembl:ENST00000443824(transcript)|go:"GO:0003883"(CTP synthase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006220"(pyrimidine nucleotide metabolic process)|go:"GO:0006241"(CTP biosynthetic process)|go:"GO:0006541"(glutamine metabolic process)|go:"GO:0019856"(pyrimidine nucleobase biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0044210"('de novo' CTP biosynthetic process)|go:"GO:0097268"(cytoophidium)|interpro:IPR004468(CTP synthase)|interpro:IPR017456(CTP synthase, N-terminal)|interpro:IPR017926|interpro:IPR027417|interpro:IPR029062|interpro:IPR033828|rcsb pdb:2V4U|rcsb pdb:2VKT|rcsb pdb:3IHL|rcsb pdb:6PK4|rcsb pdb:6PK7|reactome:R-HSA-499943|refseq:XP_006724566.1|refseq:XP_005274619.1|entrezgene/locuslink:56474(identity)	-	crc64:65A39A86CDA75D43	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:AzmIxOHHcaAoK/Paeo2aThOM2i8559292	rogid:BU/tvZTUS1d42+j0qSGAg7ND25Y9606	intact-crc:453FA878B986E2BC|rigid:W3tjJMSZcOCTqlcWwqXtIEyUQy8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UKT9	uniprotkb:Q02831	intact:EBI-747204|uniprotkb:Q8WWQ9|uniprotkb:Q8WWR0|uniprotkb:Q8WWR1|uniprotkb:Q8WWR2|uniprotkb:Q8WWR3|uniprotkb:Q8N574|uniprotkb:B4DVV5|uniprotkb:Q69BL6|uniprotkb:Q69BL7|uniprotkb:Q69BL8|uniprotkb:Q69BL9|uniprotkb:Q69BM0|uniprotkb:Q69BM1|uniprotkb:Q69BM2|uniprotkb:Q69BM3|uniprotkb:Q69BM5|ensembl:ENSP00000344544	intact:EBI-31828|uniprotkb:D6W3T9|ensemblfungi:YPL077C	psi-mi:ikzf3_human(display_long)|uniprotkb:ZNFN1A3(gene name synonym)|uniprotkb:Ikaros family zinc finger protein 3(gene name synonym)|uniprotkb:IKZF3(gene name)|psi-mi:IKZF3(display_short)	psi-mi:yp077_yeast(display_long)|uniprotkb:YPL077C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11545134|imex:IM-24995-2404	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001271443.1|refseq:NP_001271444.1|refseq:NP_036613.2|refseq:NP_899051.1|refseq:NP_899052.1|refseq:NP_899053.1|refseq:NP_899054.1|refseq:NP_899055.1|refseq:NP_001271445.1|refseq:NP_001244337.1|refseq:NP_001244338.1|refseq:NP_001244339.1|refseq:NP_001244340.1|refseq:NP_001244341.1|refseq:NP_001244342.1|refseq:NP_001244343.1|ensembl:ENSG00000161405(gene)|ensembl:ENST00000346872(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007498"(mesoderm development)|go:"GO:0009617"(response to bacterium)|go:"GO:0030888"(regulation of B cell proliferation)|go:"GO:0042113"(B cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045577"(regulation of B cell differentiation)|go:"GO:0045619"(regulation of lymphocyte differentiation)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|go:"GO:0046872"(metal ion binding)|dip:DIP-56975N|entrezgene/locuslink:22806(identity)	sgd:S000005998|refseq:NP_015248.1|dip:DIP-4022N|ensemblfungi:YPL077C(gene)|ensemblfungi:YPL077C_mRNA(transcript)|sgd:YPL077C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:2Kp6LefSLfK5VIiE6DmQusFIfMY9606	rogid:yqOn4GWKNmFZ7UvGmyBEpgoyKlA559292	intact-crc:348096E4A83BAA62|rigid:oScBJtu7xWOjgUIb5f5LQdYTiGI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q03020	uniprotkb:Q93062-3	intact:EBI-29901|uniprotkb:D6W3N2|ensemblfungi:YPL135W	intact:EBI-740343|ensembl:ENSP00000340176	psi-mi:isu1_yeast(display_long)|uniprotkb:YPL135W(locus name)|uniprotkb:Iron sulfur cluster scaffold protein 1(gene name synonym)|uniprotkb:ISU1(gene name)|psi-mi:ISU1(display_short)|uniprotkb:NUA1(gene name synonym)	psi-mi:q93062-3(display_long)|uniprotkb:RBPMS(gene name)|psi-mi:RBPMS(display_short)|uniprotkb:HERMES(gene name synonym)|uniprotkb:Heart and RRM expressed sequence(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11545199|imex:IM-24995-2411	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015190.1|sgd:S000006056|dip:DIP-6556N|mint:Q03020|ensemblfungi:YPL135W(gene)|ensemblfungi:YPL135W_mRNA(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005506"(iron ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR002871(NIF system FeS cluster assembly, NifU, N-terminal)|interpro:IPR011339(ISC system FeS cluster assembly, IscU scaffold)|rcsb pdb:5T0V|rcsb pdb:5TRE|reactome:R-SCE-1362409|sgd:YPL135W(identity)	intact:EBI-740322(rbpms_human)|uniprotkb:Q93062-3(isoform-parent)|ensembl:ENSG00000157110(gene)|ensembl:ENST00000339877(transcript)|entrezgene/locuslink:11030(identity)	-	crc64:E240845A27D2E9EE	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:zpPseOgZoK3cF+mCetzw05ct9Kc559292	rogid:nlPMQAJoKEbPYBwsL3xodmCKd7c9606	intact-crc:04405ABE9D0BE13F|rigid:p2Ku2KyhTX79IL6qo7CX0bDyGDc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q13643	uniprotkb:Q03020	intact:EBI-741101|ensembl:ENSP00000362107|uniprotkb:Q6I9T0|uniprotkb:Q9BVA2|uniprotkb:D3DPT6	intact:EBI-29901|uniprotkb:D6W3N2|ensemblfungi:YPL135W	psi-mi:fhl3_human(display_long)|uniprotkb:FHL3(gene name)|psi-mi:FHL3(display_short)|uniprotkb:SLIM2(gene name synonym)|uniprotkb:Skeletal muscle LIM-protein 2(gene name synonym)	psi-mi:isu1_yeast(display_long)|uniprotkb:YPL135W(locus name)|uniprotkb:Iron sulfur cluster scaffold protein 1(gene name synonym)|uniprotkb:ISU1(gene name)|psi-mi:ISU1(display_short)|uniprotkb:NUA1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11545190|imex:IM-24995-2410	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004459.2|ensembl:ENSG00000183386(gene)|ensembl:ENST00000373016(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005925"(focal adhesion)|go:"GO:0007517"(muscle organ development)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0046872"(metal ion binding)|interpro:IPR001781(Zinc finger, LIM-type)|mint:Q13643|rcsb pdb:1WYH|rcsb pdb:2CUQ|rcsb pdb:2EHE|interpro:IPR037987|refseq:NP_001230807.1|dip:DIP-42030N|entrezgene/locuslink:2275(identity)	refseq:NP_015190.1|sgd:S000006056|dip:DIP-6556N|mint:Q03020|ensemblfungi:YPL135W(gene)|ensemblfungi:YPL135W_mRNA(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005506"(iron ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR002871(NIF system FeS cluster assembly, NifU, N-terminal)|interpro:IPR011339(ISC system FeS cluster assembly, IscU scaffold)|rcsb pdb:5T0V|rcsb pdb:5TRE|reactome:R-SCE-1362409|sgd:YPL135W(identity)	-	-	crc64:E240845A27D2E9EE	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:RAo+b/VgFSnHSbgR+zXuxJvypxM9606	rogid:zpPseOgZoK3cF+mCetzw05ct9Kc559292	intact-crc:142B10E91AFFA8E3|rigid:7JjiiY117RFpQJOaWkGL36p7ibY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q03020	uniprotkb:P61289	intact:EBI-29901|uniprotkb:D6W3N2|ensemblfungi:YPL135W	intact:EBI-355546|uniprotkb:O35563|uniprotkb:P97373|uniprotkb:Q12920|uniprotkb:Q13172|uniprotkb:Q9BQD9|uniprotkb:A8K9A3|ensembl:ENSP00000466794	psi-mi:isu1_yeast(display_long)|uniprotkb:YPL135W(locus name)|uniprotkb:Iron sulfur cluster scaffold protein 1(gene name synonym)|uniprotkb:ISU1(gene name)|psi-mi:ISU1(display_short)|uniprotkb:NUA1(gene name synonym)	psi-mi:psme3_human(display_long)|uniprotkb:PSME3(gene name)|psi-mi:PSME3(display_short)|uniprotkb:Proteasome activator 28 subunit gamma(gene name synonym)|uniprotkb:Activator of multicatalytic protease subunit 3(gene name synonym)|uniprotkb:11S regulator complex subunit gamma(gene name synonym)|uniprotkb:Ki nuclear autoantigen(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11545181|imex:IM-24995-2409	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015190.1|sgd:S000006056|dip:DIP-6556N|mint:Q03020|ensemblfungi:YPL135W(gene)|ensemblfungi:YPL135W_mRNA(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005506"(iron ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR002871(NIF system FeS cluster assembly, NifU, N-terminal)|interpro:IPR011339(ISC system FeS cluster assembly, IscU scaffold)|rcsb pdb:5T0V|rcsb pdb:5TRE|reactome:R-SCE-1362409|sgd:YPL135W(identity)	refseq:NP_005780.2|refseq:NP_789839.1|ensembl:ENSG00000131467(gene)|ensembl:ENST00000590720(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0008537"(proteasome activator complex)|go:"GO:0010950"(positive regulation of endopeptidase activity)|go:"GO:0016020"(membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0061133"(endopeptidase activator activity)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0097371"(MDM2/MDM4 family protein binding)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR003185(Proteasome activator pa28, REG alpha subunit)|interpro:IPR003186(Proteasome activator pa28, REG beta subunit)|interpro:IPR009077(Proteasome activator pa28, REG alpha/beta subunit)|interpro:IPR036252|interpro:IPR036996|interpro:IPR036997|mint:P61289|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|entrezgene/locuslink:10197(identity)	-	crc64:E240845A27D2E9EE	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:zpPseOgZoK3cF+mCetzw05ct9Kc559292	rogid:6EQY2Kj3Juf++m4eBDzPWMgbC2k9606	intact-crc:2A675287D1B7C8E3|rigid:dQyLm0cBx4VWs2S9MCLhvoIl1/4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P19012	uniprotkb:Q03020	intact:EBI-739566|uniprotkb:Q53XV8|uniprotkb:Q9BUG4|uniprotkb:B3KQY1|uniprotkb:B3KRA2|uniprotkb:E0CX14|ensembl:ENSP00000254043|ensembl:ENSP00000377546	intact:EBI-29901|uniprotkb:D6W3N2|ensemblfungi:YPL135W	psi-mi:k1c15_human(display_long)|uniprotkb:KRT15(gene name)|psi-mi:KRT15(display_short)|uniprotkb:KRTB(gene name synonym)|uniprotkb:Cytokeratin-15(gene name synonym)|uniprotkb:Keratin-15(gene name synonym)	psi-mi:isu1_yeast(display_long)|uniprotkb:YPL135W(locus name)|uniprotkb:Iron sulfur cluster scaffold protein 1(gene name synonym)|uniprotkb:ISU1(gene name)|psi-mi:ISU1(display_short)|uniprotkb:NUA1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11545172|imex:IM-24995-2408	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002266.2|ensembl:ENSG00000171346(gene)|ensembl:ENST00000254043(transcript)|ensembl:ENST00000393976(transcript)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0008544"(epidermis development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097110"(scaffold protein binding)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR039008|mint:P19012|reactome:R-HSA-6805567|reactome:R-HSA-6809371|entrezgene/locuslink:3866(identity)	refseq:NP_015190.1|sgd:S000006056|dip:DIP-6556N|mint:Q03020|ensemblfungi:YPL135W(gene)|ensemblfungi:YPL135W_mRNA(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005506"(iron ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR002871(NIF system FeS cluster assembly, NifU, N-terminal)|interpro:IPR011339(ISC system FeS cluster assembly, IscU scaffold)|rcsb pdb:5T0V|rcsb pdb:5TRE|reactome:R-SCE-1362409|sgd:YPL135W(identity)	-	-	crc64:E240845A27D2E9EE	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:WrZQBYQvrWcfrR5ojWXrXp6spPE9606	rogid:zpPseOgZoK3cF+mCetzw05ct9Kc559292	intact-crc:DD5E6F648E10304B|rigid:v0AqN/Dy/CE4nd/2PzCo5gJ90m4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q03020	uniprotkb:Q969J2	intact:EBI-29901|uniprotkb:D6W3N2|ensemblfungi:YPL135W	intact:EBI-2818641|uniprotkb:B2RE32|uniprotkb:Q5U7L4|intact:EBI-28979011|ensembl:ENSP00000366509	psi-mi:isu1_yeast(display_long)|uniprotkb:YPL135W(locus name)|uniprotkb:Iron sulfur cluster scaffold protein 1(gene name synonym)|uniprotkb:ISU1(gene name)|psi-mi:ISU1(display_short)|uniprotkb:NUA1(gene name synonym)	psi-mi:zksc4_human(display_long)|uniprotkb:ZKSCAN4(gene name)|psi-mi:ZKSCAN4(display_short)|uniprotkb:ZNF307(gene name synonym)|uniprotkb:ZNF427(gene name synonym)|uniprotkb:P373c6.1(gene name synonym)|uniprotkb:Zinc finger protein 307(gene name synonym)|uniprotkb:Zinc finger protein 427(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11545208|imex:IM-24995-2412	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015190.1|sgd:S000006056|dip:DIP-6556N|mint:Q03020|ensemblfungi:YPL135W(gene)|ensemblfungi:YPL135W_mRNA(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005506"(iron ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR002871(NIF system FeS cluster assembly, NifU, N-terminal)|interpro:IPR011339(ISC system FeS cluster assembly, IscU scaffold)|rcsb pdb:5T0V|rcsb pdb:5TRE|reactome:R-SCE-1362409|sgd:YPL135W(identity)	refseq:NP_061983.2|ensembl:ENSP00000366509|ensembl:ENSG00000187626(gene)|ensembl:ENST00000377294(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|interpro:IPR038269|mint:Q969J2|reactome:R-HSA-212436|refseq:XP_005249152.1|entrezgene/locuslink:387032(identity)	-	crc64:E240845A27D2E9EE	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:zpPseOgZoK3cF+mCetzw05ct9Kc559292	rogid:5TWhAtzfmCXHkOSbjKwjgLIsCcs9606	intact-crc:C7BB909E9DFCABB3|rigid:oyK6B/NIQxzojwQvcUz5rhG6Ilw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q03063	uniprotkb:P63279	intact:EBI-29752|uniprotkb:D6W3W5|ensemblfungi:YPL049C	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	psi-mi:dig1_yeast(display_long)|uniprotkb:DIG1(gene name)|psi-mi:DIG1(display_short)|uniprotkb:Regulator of sterile twelve 1(gene name synonym)|uniprotkb:Regulator of STE12 protein 1(gene name synonym)|uniprotkb:RST1(gene name synonym)|uniprotkb:P7102.02(orf name)|uniprotkb:YPL049C(locus name)	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11545245|imex:IM-24995-2416	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005970|refseq:NP_015276.1|dip:DIP-1291N|mint:Q03063|ensemblfungi:YPL049C(gene)|ensemblfungi:YPL049C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0008134"(transcription factor binding)|go:"GO:0046020"(negative regulation of transcription from RNA polymerase II promoter by pheromones)|go:"GO:1900240"(negative regulation of phenotypic switching)|go:"GO:1990526"(Ste12p-Dig1p-Dig2p complex)|go:"GO:1990527"(Tec1p-Ste12p-Dig1p complex)|go:"GO:2000218"(negative regulation of invasive growth in response to glucose limitation)|go:"GO:2000221"(negative regulation of pseudohyphal growth)|sgd:YPL049C(identity)	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N|entrezgene/locuslink:7329(identity)	-	crc64:2D27F9878BFADD30	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Qt+hpsHdt+kIqMB+GKG4AYKLgOQ559292	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	intact-crc:27AB291BD9B23303|rigid:Umtwr71MyQ/+i5yADc7EBy2nXJs	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P23497-2	uniprotkb:Q03063	intact:EBI-6589365|ensembl:ENSP00000386404	intact:EBI-29752|uniprotkb:D6W3W5|ensemblfungi:YPL049C	psi-mi:p23497-2(display_long)|uniprotkb:SP100(isoform synonym)|uniprotkb:SP100(gene name)|psi-mi:SP100(display_short)|uniprotkb:Nuclear dot-associated Sp100 protein(gene name synonym)|uniprotkb:Speckled 100 kDa(gene name synonym)|uniprotkb:SP100A(isoform synonym)	psi-mi:dig1_yeast(display_long)|uniprotkb:DIG1(gene name)|psi-mi:DIG1(display_short)|uniprotkb:Regulator of sterile twelve 1(gene name synonym)|uniprotkb:Regulator of STE12 protein 1(gene name synonym)|uniprotkb:RST1(gene name synonym)|uniprotkb:P7102.02(orf name)|uniprotkb:YPL049C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11545236|imex:IM-24995-2415	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-751145(isoform-parent)|uniprotkb:P23497-2(isoform-parent)|ensembl:ENSG00000067066(gene)|ensembl:ENST00000409341(transcript)|entrezgene/locuslink:6672(identity)	sgd:S000005970|refseq:NP_015276.1|dip:DIP-1291N|mint:Q03063|ensemblfungi:YPL049C(gene)|ensemblfungi:YPL049C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0008134"(transcription factor binding)|go:"GO:0046020"(negative regulation of transcription from RNA polymerase II promoter by pheromones)|go:"GO:1900240"(negative regulation of phenotypic switching)|go:"GO:1990526"(Ste12p-Dig1p-Dig2p complex)|go:"GO:1990527"(Tec1p-Ste12p-Dig1p complex)|go:"GO:2000218"(negative regulation of invasive growth in response to glucose limitation)|go:"GO:2000221"(negative regulation of pseudohyphal growth)|sgd:YPL049C(identity)	-	isoform-comment:Major isoform.	crc64:2D27F9878BFADD30	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:HrcogLANB///4vkSYtZ7OtzOb2k9606	rogid:Qt+hpsHdt+kIqMB+GKG4AYKLgOQ559292	intact-crc:426A730DB4499A55|rigid:gd24i9x60yUV9LMH26ANwDUHUoo	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O14641	uniprotkb:Q03063	intact:EBI-740850|ensembl:ENSP00000005340|uniprotkb:Q53XM0|uniprotkb:D3DTN3	intact:EBI-29752|uniprotkb:D6W3W5|ensemblfungi:YPL049C	psi-mi:dvl2_human(display_long)|uniprotkb:DSH homolog 2(gene name synonym)|uniprotkb:DVL2(gene name)|psi-mi:DVL2(display_short)	psi-mi:dig1_yeast(display_long)|uniprotkb:DIG1(gene name)|psi-mi:DIG1(display_short)|uniprotkb:Regulator of sterile twelve 1(gene name synonym)|uniprotkb:Regulator of STE12 protein 1(gene name synonym)|uniprotkb:RST1(gene name synonym)|uniprotkb:P7102.02(orf name)|uniprotkb:YPL049C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11545227|imex:IM-24995-2414	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004413.1|ensembl:ENSG00000004975(gene)|ensembl:ENST00000005340(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005109"(frizzled binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0007507"(heart development)|go:"GO:0016235"(aggresome)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044340"(canonical Wnt signaling pathway involved in regulation of cell proliferation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0150012"(positive regulation of neuron projection arborization)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008341(Dishevelled-2 region)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:O14641|rcsb pdb:2REY|rcsb pdb:3CBX|rcsb pdb:3CBY|rcsb pdb:3CBZ|rcsb pdb:3CC0|rcsb pdb:4WIP|rcsb pdb:5LNP|rcsb pdb:5SUY|rcsb pdb:5SUZ|rcsb pdb:6IW3|rcsb pdb:6JCK|reactome:R-HSA-201681|reactome:R-HSA-201688|reactome:R-HSA-2028269|reactome:R-HSA-4086400|reactome:R-HSA-4608870|reactome:R-HSA-4641258|reactome:R-HSA-4641262|reactome:R-HSA-5099900|reactome:R-HSA-5368598|reactome:R-HSA-5663220|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9673324|ensembl:ENSP00000005340|dip:DIP-34433N|entrezgene/locuslink:1856(identity)	sgd:S000005970|refseq:NP_015276.1|dip:DIP-1291N|mint:Q03063|ensemblfungi:YPL049C(gene)|ensemblfungi:YPL049C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0008134"(transcription factor binding)|go:"GO:0046020"(negative regulation of transcription from RNA polymerase II promoter by pheromones)|go:"GO:1900240"(negative regulation of phenotypic switching)|go:"GO:1990526"(Ste12p-Dig1p-Dig2p complex)|go:"GO:1990527"(Tec1p-Ste12p-Dig1p complex)|go:"GO:2000218"(negative regulation of invasive growth in response to glucose limitation)|go:"GO:2000221"(negative regulation of pseudohyphal growth)|sgd:YPL049C(identity)	-	-	crc64:2D27F9878BFADD30	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:2Vdc8oRnT4Mz/j+EXQXrL3AszOc9606	rogid:Qt+hpsHdt+kIqMB+GKG4AYKLgOQ559292	intact-crc:086A6F150568AA91|rigid:/wBHfqjPn6GO0FbXwA2Su0E5RvM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q03020	uniprotkb:Q9Y3Q8	intact:EBI-29901|uniprotkb:D6W3N2|ensemblfungi:YPL135W	intact:EBI-739485|uniprotkb:A8MWR6|ensembl:ENSP00000300181|uniprotkb:A4D2C3|uniprotkb:D6W5V9	psi-mi:isu1_yeast(display_long)|uniprotkb:YPL135W(locus name)|uniprotkb:Iron sulfur cluster scaffold protein 1(gene name synonym)|uniprotkb:ISU1(gene name)|psi-mi:ISU1(display_short)|uniprotkb:NUA1(gene name synonym)	psi-mi:t22d4_human(display_long)|uniprotkb:TSC22D4(gene name)|psi-mi:TSC22D4(display_short)|uniprotkb:TILZ2(gene name synonym)|uniprotkb:TSC22-related-inducible leucine zipper protein 2(gene name synonym)|uniprotkb:Tsc-22-like protein THG-1(gene name synonym)|uniprotkb:THG1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11545217|imex:IM-24995-2413	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015190.1|sgd:S000006056|dip:DIP-6556N|mint:Q03020|ensemblfungi:YPL135W(gene)|ensemblfungi:YPL135W_mRNA(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005506"(iron ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR002871(NIF system FeS cluster assembly, NifU, N-terminal)|interpro:IPR011339(ISC system FeS cluster assembly, IscU scaffold)|rcsb pdb:5T0V|rcsb pdb:5TRE|reactome:R-SCE-1362409|sgd:YPL135W(identity)	ensembl:ENSG00000166925(gene)|ensembl:ENST00000300181(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006970"(response to osmotic stress)|interpro:IPR000580(TSC-22 / Dip / Bun)|interpro:IPR042553|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|refseq:NP_112197.1|refseq:NP_001289972.1|entrezgene/locuslink:81628(identity)	-	crc64:E240845A27D2E9EE	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:zpPseOgZoK3cF+mCetzw05ct9Kc559292	rogid:eL12cHY76zEPOXzT1HFKPSckS8Y9606	intact-crc:040D19998B503B02|rigid:7/fk/v7+VK0rnscXpMwupZD/a2Y	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q03338	uniprotkb:Q13422-7	intact:EBI-421|uniprotkb:D6VT97|ensemblfungi:YDR473C	intact:EBI-11522367|ensembl:ENSP00000352123|ensembl:ENSP00000413025	psi-mi:prp3_yeast(display_long)|uniprotkb:PRP3(gene name)|psi-mi:PRP3(display_short)|uniprotkb:RNA3(gene name synonym)|uniprotkb:YDR473C(locus name)|uniprotkb:D8035.16(orf name)|uniprotkb:Pre-mRNA-splicing factor 3(gene name synonym)	psi-mi:q13422-7(display_long)|uniprotkb:IKZF1(gene name)|psi-mi:IKZF1(display_short)|uniprotkb:IK1(gene name synonym)|uniprotkb:IKAROS(gene name synonym)|uniprotkb:Ikaros family zinc finger protein 1(gene name synonym)|uniprotkb:LYF1(gene name synonym)|uniprotkb:Lymphoid transcription factor LyF-1(gene name synonym)|uniprotkb:ZNFN1A1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11545281|imex:IM-24995-2420	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002881|refseq:NP_010761.3|ensemblfungi:YDR473C(gene)|ensemblfungi:YDR473C_mRNA(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|interpro:IPR010541(Protein of unknown function DUF1115)|interpro:IPR013881(Pre-mRNA-splicing factor 3)|interpro:IPR027104|rcsb pdb:3JCM|rcsb pdb:4YHU|rcsb pdb:4YHV|rcsb pdb:4YHW|rcsb pdb:5GAN|rcsb pdb:5GAP|rcsb pdb:5NRL|rcsb pdb:5ZWM|rcsb pdb:5ZWO|dip:DIP-5266N|mint:Q03338|sgd:YDR473C(identity)	intact:EBI-745305(isoform-parent)|ensembl:ENSG00000185811(gene)|ensembl:ENST00000359197(transcript)|ensembl:ENST00000439701(transcript)|uniprotkb:Q13422-7(isoform-parent)|entrezgene/locuslink:10320(identity)	-	crc64:E977FD9F708BDD91	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:KE0Y/kRXTq9LXt4PGsKnRcY7Sqg559292	rogid:ou/ovXYoMneBNVp4pj38VxenfyY9606	intact-crc:F34A1936873B6184|rigid:sTPJqRmLHOwyDW1RvdBNcHNgQ4U	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q03338	uniprotkb:O14641	intact:EBI-421|uniprotkb:D6VT97|ensemblfungi:YDR473C	intact:EBI-740850|ensembl:ENSP00000005340|uniprotkb:Q53XM0|uniprotkb:D3DTN3	psi-mi:prp3_yeast(display_long)|uniprotkb:PRP3(gene name)|psi-mi:PRP3(display_short)|uniprotkb:RNA3(gene name synonym)|uniprotkb:YDR473C(locus name)|uniprotkb:D8035.16(orf name)|uniprotkb:Pre-mRNA-splicing factor 3(gene name synonym)	psi-mi:dvl2_human(display_long)|uniprotkb:DSH homolog 2(gene name synonym)|uniprotkb:DVL2(gene name)|psi-mi:DVL2(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11545272|imex:IM-24995-2419	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002881|refseq:NP_010761.3|ensemblfungi:YDR473C(gene)|ensemblfungi:YDR473C_mRNA(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|interpro:IPR010541(Protein of unknown function DUF1115)|interpro:IPR013881(Pre-mRNA-splicing factor 3)|interpro:IPR027104|rcsb pdb:3JCM|rcsb pdb:4YHU|rcsb pdb:4YHV|rcsb pdb:4YHW|rcsb pdb:5GAN|rcsb pdb:5GAP|rcsb pdb:5NRL|rcsb pdb:5ZWM|rcsb pdb:5ZWO|dip:DIP-5266N|mint:Q03338|sgd:YDR473C(identity)	refseq:NP_004413.1|ensembl:ENSG00000004975(gene)|ensembl:ENST00000005340(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005109"(frizzled binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0007507"(heart development)|go:"GO:0016235"(aggresome)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044340"(canonical Wnt signaling pathway involved in regulation of cell proliferation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0150012"(positive regulation of neuron projection arborization)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008341(Dishevelled-2 region)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:O14641|rcsb pdb:2REY|rcsb pdb:3CBX|rcsb pdb:3CBY|rcsb pdb:3CBZ|rcsb pdb:3CC0|rcsb pdb:4WIP|rcsb pdb:5LNP|rcsb pdb:5SUY|rcsb pdb:5SUZ|rcsb pdb:6IW3|rcsb pdb:6JCK|reactome:R-HSA-201681|reactome:R-HSA-201688|reactome:R-HSA-2028269|reactome:R-HSA-4086400|reactome:R-HSA-4608870|reactome:R-HSA-4641258|reactome:R-HSA-4641262|reactome:R-HSA-5099900|reactome:R-HSA-5368598|reactome:R-HSA-5663220|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9673324|ensembl:ENSP00000005340|dip:DIP-34433N|entrezgene/locuslink:1856(identity)	-	crc64:E977FD9F708BDD91	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:KE0Y/kRXTq9LXt4PGsKnRcY7Sqg559292	rogid:2Vdc8oRnT4Mz/j+EXQXrL3AszOc9606	intact-crc:1FE11D7A213A6E4D|rigid:3nza4C1jHUkLd7cvGrIQJ1bmWA4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q03262	uniprotkb:O43809	intact:EBI-27609|uniprotkb:D6W0A5|ensemblfungi:YMR278W	intact:EBI-355720|uniprotkb:Q6IB85|uniprotkb:Q6NE84|ensembl:ENSP00000300291	psi-mi:pgm3_yeast(display_long)|uniprotkb:PRM15(gene name)|psi-mi:PRM15(display_short)|uniprotkb:PGM3(gene name synonym)|uniprotkb:Phosphoglucomutase 3(gene name synonym)|uniprotkb:YM8021.04(orf name)|uniprotkb:YMR278W(locus name)	psi-mi:cpsf5_human(display_long)|uniprotkb:NUDT21(gene name)|psi-mi:NUDT21(display_short)|uniprotkb:CFIM25(gene name synonym)|uniprotkb:CPSF25(gene name synonym)|uniprotkb:CPSF5(gene name synonym)|uniprotkb:Cleavage and polyadenylation specificity factor 25 kDa subunit(gene name synonym)|uniprotkb:Nucleoside diphosphate-linked moiety X motif 21(gene name synonym)|uniprotkb:Cleavage factor Im complex 25 kDa subunit(gene name synonym)|uniprotkb:Nudix hydrolase 21(gene name synonym)|uniprotkb:Pre-mRNA cleavage factor Im 68 kDa subunit(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11545263|imex:IM-24995-2418	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000004891|refseq:NP_014005.1|reactome:R-SCE-3322077|reactome:R-SCE-71336|reactome:R-SCE-6798695|dip:DIP-5066N|reactome:R-SCE-70171|reactome:R-SCE-70221|reactome:R-SCE-70370|interpro:IPR036900|interpro:IPR016066(Alpha-D-phosphohexomutase, conserved site)|ensemblfungi:YMR278W(gene)|ensemblfungi:YMR278W_mRNA(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006148"(inosine catabolic process)|go:"GO:0006166"(purine ribonucleoside salvage)|go:"GO:0008973"(phosphopentomutase activity)|go:"GO:0046115"(guanosine catabolic process)|interpro:IPR005843(Alpha-D-phosphohexomutase, C-terminal)|interpro:IPR005844(Alpha-D-phosphohexomutase, alpha/beta/alpha domain I)|interpro:IPR005845(Alpha-D-phosphohexomutase, alpha/beta/alpha domain II)|interpro:IPR005846(Alpha-D-phosphohexomutase, alpha/beta/alpha domain III)|interpro:IPR016055(Alpha-D-phosphohexomutase, alpha/beta/alpha I, II and III)|sgd:YMR278W(identity)	refseq:NP_008937.1|ensembl:ENSG00000167005(gene)|ensembl:ENST00000300291(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0005849"(mRNA cleavage factor complex)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0006397"(mRNA processing)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0031439"(positive regulation of mRNA cleavage)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0042382"(paraspeckles)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051290"(protein heterotetramerization)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|go:"GO:0110104"(mRNA alternative polyadenylation)|go:"GO:1900365"(positive regulation of mRNA polyadenylation)|go:"GO:1990120"(messenger ribonucleoprotein complex assembly)|go:"GO:2000738"(positive regulation of stem cell differentiation)|go:"GO:2000975"(positive regulation of pro-B cell differentiation)|interpro:IPR000086(NUDIX hydrolase, core)|interpro:IPR015797(NUDIX)|interpro:IPR016706(Cleavage and polyadenylation specificity factor, 25 kDa subunit)|mint:O43809|rcsb pdb:2CL3|rcsb pdb:2J8Q|rcsb pdb:3BAP|rcsb pdb:3BHO|rcsb pdb:3MDG|rcsb pdb:3MDI|rcsb pdb:3N9U|rcsb pdb:3P5T|rcsb pdb:3P6Y|rcsb pdb:3Q2S|rcsb pdb:3Q2T|rcsb pdb:5R4P|rcsb pdb:5R4Q|rcsb pdb:5R4R|rcsb pdb:5R4S|rcsb pdb:5R4T|rcsb pdb:5R4U|rcsb pdb:5R64|rcsb pdb:5R65|rcsb pdb:5R66|rcsb pdb:5R67|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-77595|dip:DIP-42502N|entrezgene/locuslink:11051(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:hEeb0XLedLqmf04ufZaiMNcwQXE559292	rogid:Acad4mYVuS+Eox+X2CH8PYUkGAA9606	intact-crc:C8512B7A9372EBFF|rigid:XWdqPBSj+MwrHkF4/LloWEX52fE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q13422-7	uniprotkb:Q03233	intact:EBI-11522367|ensembl:ENSP00000352123|ensembl:ENSP00000413025	intact:EBI-27402|uniprotkb:D6W008|ensemblfungi:YMR184W	psi-mi:q13422-7(display_long)|uniprotkb:IKZF1(gene name)|psi-mi:IKZF1(display_short)|uniprotkb:IK1(gene name synonym)|uniprotkb:IKAROS(gene name synonym)|uniprotkb:Ikaros family zinc finger protein 1(gene name synonym)|uniprotkb:LYF1(gene name synonym)|uniprotkb:Lymphoid transcription factor LyF-1(gene name synonym)|uniprotkb:ZNFN1A1(gene name synonym)	psi-mi:add37_yeast(display_long)|uniprotkb:YM8010.14(orf name)|uniprotkb:YMR184W(locus name)|uniprotkb:ADD37(gene name)|psi-mi:ADD37(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11545254|imex:IM-24995-2417	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-745305(isoform-parent)|ensembl:ENSG00000185811(gene)|ensembl:ENST00000359197(transcript)|ensembl:ENST00000439701(transcript)|uniprotkb:Q13422-7(isoform-parent)|entrezgene/locuslink:10320(identity)	sgd:S000004796|refseq:NP_013909.1|dip:DIP-3848N|ensemblfungi:YMR184W(gene)|ensemblfungi:YMR184W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|sgd:YMR184W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:ou/ovXYoMneBNVp4pj38VxenfyY9606	rogid:1f4WwSzzLoaYs7mq9XrVap58RWE559292	intact-crc:63BDF4D8F6C8000B|rigid:Q741FjeixosXKGt7X2veqa1bpo0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96BA8	uniprotkb:Q03362	intact:EBI-6942903|ensembl:ENSP00000481956|intact:MINT-268046|intact:MINT-8162577|uniprotkb:Q8N2D5|uniprotkb:Q96CP0	intact:EBI-2057915|uniprotkb:D6VT99|ensemblfungi:YDR476C	psi-mi:cr3l1_human(display_long)|uniprotkb:CREB3L1(gene name)|psi-mi:CREB3L1(display_short)|uniprotkb:OASIS(gene name synonym)|uniprotkb:PSEC0238(orf name)|uniprotkb:Old astrocyte specifically-induced substance(gene name synonym)	psi-mi:yd476_yeast(display_long)|uniprotkb:YDR476C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11545317|imex:IM-24995-2424	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157613(gene)|ensembl:ENST00000621158(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0070278"(extracellular matrix constituent secretion)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029805|mint:Q96BA8|reactome:R-HSA-8874211|refseq:NP_443086.1|entrezgene/locuslink:90993(identity)	sgd:S000002884|refseq:NP_010764.1|mint:Q03362|ensemblfungi:YDR476C(gene)|ensemblfungi:YDR476C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|sgd:YDR476C(identity)	-	comment:mint|function:"Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE"	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:sMWUFmBeBBCO+T0Y2CuB/un1lBg9606	rogid:YEqaI+xtDR2srSbbY5vQtWY+h6s559292	intact-crc:C2BEC6477832535B|rigid:7R5TCt7NUJ/xrrYIJFayBGRGKLQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9C0F1	uniprotkb:Q03338	intact:EBI-744115|uniprotkb:A8K8W9|uniprotkb:B3KT53|uniprotkb:Q8IXZ4|uniprotkb:A8MW11|uniprotkb:D3DP42|ensembl:ENSP00000296519|ensembl:ENSP00000380009|ensembl:ENSP00000423153	intact:EBI-421|uniprotkb:D6VT97|ensemblfungi:YDR473C	psi-mi:cep44_human(display_long)|uniprotkb:HBV PreS1-transactivated protein 3(gene name synonym)|uniprotkb:CEP44(gene name)|psi-mi:CEP44(display_short)|uniprotkb:KIAA1712(gene name synonym)	psi-mi:prp3_yeast(display_long)|uniprotkb:PRP3(gene name)|psi-mi:PRP3(display_short)|uniprotkb:RNA3(gene name synonym)|uniprotkb:YDR473C(locus name)|uniprotkb:D8035.16(orf name)|uniprotkb:Pre-mRNA-splicing factor 3(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11545308|imex:IM-24995-2423	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001035247.1|refseq:NP_001138786.1|refseq:XP_011530587.1|refseq:XP_011530588.1|refseq:XP_011530589.1|refseq:XP_016864143.1|refseq:XP_016864144.1|ensembl:ENSG00000164118(gene)|ensembl:ENST00000296519(transcript)|ensembl:ENST00000396791(transcript)|ensembl:ENST00000503780(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007099"(centriole replication)|go:"GO:0008017"(microtubule binding)|go:"GO:0010457"(centriole-centriole cohesion)|go:"GO:0030496"(midbody)|interpro:IPR029157|interpro:IPR033603|mint:Q9C0F1|entrezgene/locuslink:80817(identity)	sgd:S000002881|refseq:NP_010761.3|ensemblfungi:YDR473C(gene)|ensemblfungi:YDR473C_mRNA(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|interpro:IPR010541(Protein of unknown function DUF1115)|interpro:IPR013881(Pre-mRNA-splicing factor 3)|interpro:IPR027104|rcsb pdb:3JCM|rcsb pdb:4YHU|rcsb pdb:4YHV|rcsb pdb:4YHW|rcsb pdb:5GAN|rcsb pdb:5GAP|rcsb pdb:5NRL|rcsb pdb:5ZWM|rcsb pdb:5ZWO|dip:DIP-5266N|mint:Q03338|sgd:YDR473C(identity)	-	-	crc64:E977FD9F708BDD91	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:gDTC64oDhudGdsssC7v+suIHZkA9606	rogid:KE0Y/kRXTq9LXt4PGsKnRcY7Sqg559292	intact-crc:0C402F4FB342078E|rigid:qeZhAvTXkppjcuZ0FEe42k4EFUM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q03338	uniprotkb:Q96BR9	intact:EBI-421|uniprotkb:D6VT97|ensemblfungi:YDR473C	intact:EBI-742740|uniprotkb:Q8IUL5|uniprotkb:Q8IWR9|uniprotkb:Q8N2Y5|uniprotkb:Q96BX0|ensembl:ENSP00000362609	psi-mi:prp3_yeast(display_long)|uniprotkb:PRP3(gene name)|psi-mi:PRP3(display_short)|uniprotkb:RNA3(gene name synonym)|uniprotkb:YDR473C(locus name)|uniprotkb:D8035.16(orf name)|uniprotkb:Pre-mRNA-splicing factor 3(gene name synonym)	psi-mi:zbt8a_human(display_long)|uniprotkb:ZBTB8A(gene name)|psi-mi:ZBTB8A(display_short)|uniprotkb:BOZF1(gene name synonym)|uniprotkb:BTB/POZ and zinc-finger domain-containing factor(gene name synonym)|uniprotkb:BTB/POZ and zinc-finger domains factor on chromosome 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11545299|imex:IM-24995-2422	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002881|refseq:NP_010761.3|ensemblfungi:YDR473C(gene)|ensemblfungi:YDR473C_mRNA(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|interpro:IPR010541(Protein of unknown function DUF1115)|interpro:IPR013881(Pre-mRNA-splicing factor 3)|interpro:IPR027104|rcsb pdb:3JCM|rcsb pdb:4YHU|rcsb pdb:4YHV|rcsb pdb:4YHW|rcsb pdb:5GAN|rcsb pdb:5GAP|rcsb pdb:5NRL|rcsb pdb:5ZWM|rcsb pdb:5ZWO|dip:DIP-5266N|mint:Q03338|sgd:YDR473C(identity)	ensembl:ENSG00000160062(gene)|ensembl:ENST00000373510(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|refseq:NP_001035531.2|refseq:NP_001278425.1|entrezgene/locuslink:653121(identity)	-	crc64:E977FD9F708BDD91	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:KE0Y/kRXTq9LXt4PGsKnRcY7Sqg559292	rogid:tsrPT2tHvuBryODKgRXnceXz9s09606	intact-crc:74F7B91EE66A5542|rigid:IVEbIOp9yqdYWIMXWUGgK0gWKck	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8NHQ1	uniprotkb:Q03338	intact:EBI-739624|ensembl:ENSP00000264982|ensembl:ENSP00000419231|uniprotkb:Q96B31|uniprotkb:Q9H2C3|uniprotkb:Q9H2Z1|uniprotkb:Q9H940|uniprotkb:D3DNE9|uniprotkb:B7Z5I8|uniprotkb:B7Z7E8|uniprotkb:F5GZX8	intact:EBI-421|uniprotkb:D6VT97|ensemblfungi:YDR473C	psi-mi:cep70_human(display_long)|uniprotkb:CEP70(gene name)|psi-mi:CEP70(display_short)|uniprotkb:BITE(gene name synonym)|uniprotkb:p10-binding protein(gene name synonym)	psi-mi:prp3_yeast(display_long)|uniprotkb:PRP3(gene name)|psi-mi:PRP3(display_short)|uniprotkb:RNA3(gene name synonym)|uniprotkb:YDR473C(locus name)|uniprotkb:D8035.16(orf name)|uniprotkb:Pre-mRNA-splicing factor 3(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11545290|imex:IM-24995-2421	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114107(gene)|ensembl:ENST00000264982(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|interpro:IPR019734|interpro:IPR037692|mint:Q8NHQ1|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|ensembl:ENST00000484888(transcript)|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_077817.2|refseq:XP_016862764.1|refseq:NP_001275893.1|refseq:NP_001275894.1|refseq:NP_001275895.1|refseq:NP_001275896.1|refseq:NP_001307527.1|refseq:NP_001307529.1|entrezgene/locuslink:80321(identity)	sgd:S000002881|refseq:NP_010761.3|ensemblfungi:YDR473C(gene)|ensemblfungi:YDR473C_mRNA(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|interpro:IPR010541(Protein of unknown function DUF1115)|interpro:IPR013881(Pre-mRNA-splicing factor 3)|interpro:IPR027104|rcsb pdb:3JCM|rcsb pdb:4YHU|rcsb pdb:4YHV|rcsb pdb:4YHW|rcsb pdb:5GAN|rcsb pdb:5GAP|rcsb pdb:5NRL|rcsb pdb:5ZWM|rcsb pdb:5ZWO|dip:DIP-5266N|mint:Q03338|sgd:YDR473C(identity)	-	-	crc64:E977FD9F708BDD91	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:S4yveQWcvdVtAUX65gqrJ5Dv0Mc9606	rogid:KE0Y/kRXTq9LXt4PGsKnRcY7Sqg559292	intact-crc:C201333471C41E37|rigid:EVMV9nZXPApYzcEVft+zDK3DXyo	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q03579	uniprotkb:Q8N6L0	intact:EBI-27640|uniprotkb:D6W0C5|ensemblfungi:YMR298W	intact:EBI-749265|uniprotkb:Q96MC3|ensembl:ENSP00000404220	psi-mi:lip1_yeast(display_long)|uniprotkb:YMR298W(locus name)|uniprotkb:LIP1(gene name)|psi-mi:LIP1(display_short)|uniprotkb:LAG1/LAC1-interacting protein 1(gene name synonym)	psi-mi:kash5_human(display_long)|uniprotkb:KASH5(gene name)|psi-mi:KASH5(display_short)|uniprotkb:CCDC155(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 155(gene name synonym)|uniprotkb:KASH domain-containing protein 5(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11545363|imex:IM-24995-2429	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014027.1|sgd:S000004913|dip:DIP-4392N|ensemblfungi:YMR298W(gene)|ensemblfungi:YMR298W_mRNA(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:0061576"(acyl-CoA ceramide synthase complex)|sgd:YMR298W(identity)	refseq:NP_653289.3|ensembl:ENSG00000161609(gene)|ensembl:ENST00000447857(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034397"(telomere localization)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051225"(spindle assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0090172"(microtubule cytoskeleton organization involved in homologous chromosome segregation)|go:"GO:0090220"(chromosome localization to nuclear envelope involved in homologous chromosome segregation)|go:"GO:0090619"(meiotic spindle pole)|interpro:IPR011992(EF-Hand type)|interpro:IPR028168|interpro:IPR028170|interpro:IPR039508|mint:Q8N6L0|rcsb pdb:6R2I|rcsb pdb:6WMF|entrezgene/locuslink:147872(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:9Z3aO01R1mik+xM40fm/dy+A/ec559292	rogid:Wl9L7AcvDHCZuKjYLn8QgGIbZTc9606	intact-crc:FB839ED3C70AD1BC|rigid:4vBKopNrNkdVE82v9RXyHdI6Soc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9BQY4	uniprotkb:Q03373	intact:EBI-372094|uniprotkb:Q9BR00|ensembl:ENSP00000360441	intact:EBI-34019|uniprotkb:D6VTA3|ensemblfungi:YDR480W	psi-mi:rhxf2_human(display_long)|uniprotkb:RHOXF2(gene name)|psi-mi:RHOXF2(display_short)|uniprotkb:THG1(gene name synonym)|uniprotkb:Paired-like homeobox protein PEPP-2(gene name synonym)|uniprotkb:Testis homeobox gene 1(gene name synonym)|uniprotkb:PEPP2(gene name synonym)	psi-mi:dig2_yeast(display_long)|uniprotkb:DIG2(gene name)|psi-mi:DIG2(display_short)|uniprotkb:Regulator of sterile twelve 2(gene name synonym)|uniprotkb:Regulator of STE12 protein 2(gene name synonym)|uniprotkb:RST2(gene name synonym)|uniprotkb:D8035.23(orf name)|uniprotkb:YDR480W(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11545354|imex:IM-24995-2428	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_115887.1|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0042802"(identical protein binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|ensembl:ENSG00000131721(gene)|ensembl:ENST00000371388(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|entrezgene/locuslink:84528(identity)	sgd:S000002888|refseq:NP_010768.1|mint:Q03373|dip:DIP-1292N|ensemblfungi:YDR480W(gene)|ensemblfungi:YDR480W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0008134"(transcription factor binding)|go:"GO:0046020"(negative regulation of transcription from RNA polymerase II promoter by pheromones)|go:"GO:1990526"(Ste12p-Dig1p-Dig2p complex)|go:"GO:2000218"(negative regulation of invasive growth in response to glucose limitation)|go:"GO:2000221"(negative regulation of pseudohyphal growth)|sgd:YDR480W(identity)	-	-	crc64:8E71278ED6D3A912	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:shpgPqf80gNt+gFDv1K+827ELUQ9606	rogid:Uh6OsQDXtmnLKMAEZHl/NTKCEYY559292	intact-crc:2D5503A3919CEF3B|rigid:fsCVKuQevcaXnW0lHqXZOKF+bPI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P63279	uniprotkb:Q03373	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	intact:EBI-34019|uniprotkb:D6VTA3|ensemblfungi:YDR480W	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:dig2_yeast(display_long)|uniprotkb:DIG2(gene name)|psi-mi:DIG2(display_short)|uniprotkb:Regulator of sterile twelve 2(gene name synonym)|uniprotkb:Regulator of STE12 protein 2(gene name synonym)|uniprotkb:RST2(gene name synonym)|uniprotkb:D8035.23(orf name)|uniprotkb:YDR480W(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11545345|imex:IM-24995-2427	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N|entrezgene/locuslink:7329(identity)	sgd:S000002888|refseq:NP_010768.1|mint:Q03373|dip:DIP-1292N|ensemblfungi:YDR480W(gene)|ensemblfungi:YDR480W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0008134"(transcription factor binding)|go:"GO:0046020"(negative regulation of transcription from RNA polymerase II promoter by pheromones)|go:"GO:1990526"(Ste12p-Dig1p-Dig2p complex)|go:"GO:2000218"(negative regulation of invasive growth in response to glucose limitation)|go:"GO:2000221"(negative regulation of pseudohyphal growth)|sgd:YDR480W(identity)	-	-	crc64:8E71278ED6D3A912	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	rogid:Uh6OsQDXtmnLKMAEZHl/NTKCEYY559292	intact-crc:B5877777B83D6CB7|rigid:ijMMvi5+BnGuI045ugOrZ5wp46A	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q03373	uniprotkb:P31947	intact:EBI-34019|uniprotkb:D6VTA3|ensemblfungi:YDR480W	intact:EBI-476295|uniprotkb:Q6FH30|uniprotkb:Q6FH51|uniprotkb:Q96DH0|ensembl:ENSP00000340989|intact:EBI-28970316	psi-mi:dig2_yeast(display_long)|uniprotkb:DIG2(gene name)|psi-mi:DIG2(display_short)|uniprotkb:Regulator of sterile twelve 2(gene name synonym)|uniprotkb:Regulator of STE12 protein 2(gene name synonym)|uniprotkb:RST2(gene name synonym)|uniprotkb:D8035.23(orf name)|uniprotkb:YDR480W(locus name)	psi-mi:1433s_human(display_long)|uniprotkb:Stratifin(gene name synonym)|uniprotkb:Epithelial cell marker protein 1(gene name synonym)|uniprotkb:HME1(gene name synonym)|uniprotkb:SFN(gene name)|psi-mi:SFN(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11545336|imex:IM-24995-2426	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002888|refseq:NP_010768.1|mint:Q03373|dip:DIP-1292N|ensemblfungi:YDR480W(gene)|ensemblfungi:YDR480W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0008134"(transcription factor binding)|go:"GO:0046020"(negative regulation of transcription from RNA polymerase II promoter by pheromones)|go:"GO:1990526"(Ste12p-Dig1p-Dig2p complex)|go:"GO:2000218"(negative regulation of invasive growth in response to glucose limitation)|go:"GO:2000221"(negative regulation of pseudohyphal growth)|sgd:YDR480W(identity)	ensembl:ENSP00000340989|go:"GO:0010839"(negative regulation of keratinocyte proliferation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0031424"(keratinization)|ensembl:ENSG00000175793(gene)|go:"GO:0042802"(identical protein binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|ensembl:ENST00000339276(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0045606"(positive regulation of epidermal cell differentiation)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000308(14-3-3 protein)|go:"GO:0003334"(keratinocyte development)|interpro:IPR023409|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007165"(signal transduction)|go:"GO:0008426"(protein kinase C inhibitor activity)|interpro:IPR023410|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0010482"(regulation of epidermal cell division)|interpro:IPR036815|interpro:IPR037435|mint:P31947|rcsb pdb:1YWT|rcsb pdb:3IQJ|rcsb pdb:3IQU|rcsb pdb:3IQV|rcsb pdb:3LW1|rcsb pdb:3MHR|rcsb pdb:3O8I|rcsb pdb:3P1N|rcsb pdb:3P1O|rcsb pdb:3P1P|rcsb pdb:3P1Q|rcsb pdb:3P1R|rcsb pdb:3P1S|rcsb pdb:3SMK|rcsb pdb:3SML|rcsb pdb:3SMM|rcsb pdb:3SMN|rcsb pdb:3SMO|rcsb pdb:3SP5|rcsb pdb:3SPR|rcsb pdb:3T0L|rcsb pdb:3T0M|rcsb pdb:3U9X|rcsb pdb:3UX0|rcsb pdb:4DAT|rcsb pdb:4DAU|rcsb pdb:4DHM|rcsb pdb:4DHN|rcsb pdb:4DHO|rcsb pdb:4DHP|rcsb pdb:4DHQ|rcsb pdb:4DHR|rcsb pdb:4DHS|rcsb pdb:4DHT|rcsb pdb:4DHU|rcsb pdb:4FL5|rcsb pdb:4FR3|rcsb pdb:4IEA|rcsb pdb:4JC3|rcsb pdb:4JDD|rcsb pdb:4QLI|rcsb pdb:4Y32|rcsb pdb:4Y3B|rcsb pdb:4Y5I|rcsb pdb:5BTV|rcsb pdb:5HF3|rcsb pdb:1YZ5|rcsb pdb:5LTW|rcsb pdb:5LU1|rcsb pdb:5LU2|rcsb pdb:5MHC|rcsb pdb:5MOC|rcsb pdb:5MXO|rcsb pdb:7O34|rcsb pdb:7O3A|rcsb pdb:7O3F|rcsb pdb:7O3P|rcsb pdb:7O3Q|rcsb pdb:7NZV|rcsb pdb:7O3R|rcsb pdb:7O3S|rcsb pdb:7O57|rcsb pdb:7O59|rcsb pdb:7O5A|rcsb pdb:7O5C|rcsb pdb:7O5D|rcsb pdb:7O5F|rcsb pdb:7O5G|rcsb pdb:7O5O|rcsb pdb:7O5P|rcsb pdb:7O5S|rcsb pdb:7O5U|rcsb pdb:7O5X|rcsb pdb:7O6F|rcsb pdb:7O6G|rcsb pdb:7O6I|rcsb pdb:7O6J|rcsb pdb:7O6K|rcsb pdb:7O6M|rcsb pdb:7O6O|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-5625740|reactome:R-HSA-5628897|rcsb pdb:6GHP|rcsb pdb:6HHP|rcsb pdb:6HKB|rcsb pdb:6HKF|rcsb pdb:6HMT|rcsb pdb:6G8Q|rcsb pdb:6HMU|rcsb pdb:6HN2|rcsb pdb:6NV2|rcsb pdb:6QDR|rcsb pdb:6QDS|rcsb pdb:6QDT|rcsb pdb:6QDU|rcsb pdb:6QHL|rcsb pdb:6QHM|rcsb pdb:6QIU|rcsb pdb:6QZR|rcsb pdb:6QZS|rcsb pdb:6R5L|rcsb pdb:6RHC|rcsb pdb:6RJL|rcsb pdb:6RJQ|rcsb pdb:6RJZ|rcsb pdb:6RK8|rcsb pdb:6RKI|rcsb pdb:6RKK|rcsb pdb:6RKM|rcsb pdb:6RL3|rcsb pdb:6RL4|rcsb pdb:6RL6|rcsb pdb:6RM5|rcsb pdb:6RM7|rcsb pdb:6RP6|rcsb pdb:6RWH|rcsb pdb:6RWI|rcsb pdb:5MYC|rcsb pdb:5N5R|rcsb pdb:5N5T|rcsb pdb:5N5W|rcsb pdb:5N75|rcsb pdb:5OEG|rcsb pdb:5OEH|rcsb pdb:5OK9|rcsb pdb:5OKF|rcsb pdb:5OM0|rcsb pdb:5OMA|rcsb pdb:6FAU|rcsb pdb:6FAV|rcsb pdb:6FAW|rcsb pdb:6FBB|rcsb pdb:6FBW|rcsb pdb:6FBY|rcsb pdb:6FCP|rcsb pdb:6FI4|rcsb pdb:6FI5|rcsb pdb:6G6X|rcsb pdb:6G8I|rcsb pdb:5MY9|rcsb pdb:6G8J|rcsb pdb:6G8K|rcsb pdb:6G8L|rcsb pdb:6G8P|rcsb pdb:6RWS|rcsb pdb:6TJM|rcsb pdb:6TL3|rcsb pdb:6RWU|rcsb pdb:6TLF|rcsb pdb:6TLG|rcsb pdb:6TM7|rcsb pdb:6TWZ|rcsb pdb:6W0L|rcsb pdb:6XWD|rcsb pdb:6XXC|rcsb pdb:6XY5|rcsb pdb:6Y18|rcsb pdb:6Y1D|rcsb pdb:6Y1J|rcsb pdb:6RX2|rcsb pdb:6S39|rcsb pdb:6S3C|rcsb pdb:6S40|rcsb pdb:6Y3M|rcsb pdb:6Y3O|rcsb pdb:6Y3R|rcsb pdb:6Y3S|rcsb pdb:6Y3V|rcsb pdb:6Y3W|rcsb pdb:6Y40|rcsb pdb:6S9Q|rcsb pdb:6Y44|rcsb pdb:6SIN|rcsb pdb:6Y58|rcsb pdb:6SIO|rcsb pdb:6Y7T|rcsb pdb:6SIP|rcsb pdb:6Y8A|rcsb pdb:6Y8B|rcsb pdb:6Y8D|rcsb pdb:6SIQ|rcsb pdb:6Y8E|rcsb pdb:6YE9|rcsb pdb:6YIA|rcsb pdb:6SLV|rcsb pdb:6YIB|rcsb pdb:6YIC|rcsb pdb:6YLU|rcsb pdb:6YOW|rcsb pdb:6YOX|rcsb pdb:6YOY|rcsb pdb:6YP2|rcsb pdb:6YP3|rcsb pdb:6YP8|rcsb pdb:6SLW|rcsb pdb:6SLX|rcsb pdb:6T5F|rcsb pdb:6T5H|rcsb pdb:6T80|rcsb pdb:6TCH|rcsb pdb:6YPL|rcsb pdb:6YPY|rcsb pdb:6YQ2|rcsb pdb:6ZCJ|rcsb pdb:7AEW|rcsb pdb:7AOG|rcsb pdb:7AXN|rcsb pdb:7AYF|rcsb pdb:7AZ1|rcsb pdb:7AZ2|rcsb pdb:7BDP|rcsb pdb:7BDT|rcsb pdb:7BDY|rcsb pdb:7BFW|rcsb pdb:7BG3|rcsb pdb:7BGQ|rcsb pdb:7BGR|rcsb pdb:7BGV|rcsb pdb:7BGW|rcsb pdb:7BI3|rcsb pdb:7BIQ|rcsb pdb:7BIY|rcsb pdb:7BJF|rcsb pdb:7BJL|rcsb pdb:7BJW|rcsb pdb:7BKH|rcsb pdb:7NFW|rcsb pdb:7NIF|rcsb pdb:7NIG|rcsb pdb:7NIX|rcsb pdb:7NJ6|rcsb pdb:7NJ8|rcsb pdb:7NJ9|rcsb pdb:7NJA|rcsb pdb:7NJB|rcsb pdb:7NK3|rcsb pdb:7NK5|rcsb pdb:7NLA|rcsb pdb:7NLE|rcsb pdb:7NM1|rcsb pdb:7NM3|rcsb pdb:7NM9|rcsb pdb:7NQP|rcsb pdb:7NR7|rcsb pdb:7NRK|rcsb pdb:7NRL|rcsb pdb:7NSV|rcsb pdb:7NV4|rcsb pdb:7NVI|rcsb pdb:7NWS|rcsb pdb:7NXS|rcsb pdb:7NXT|rcsb pdb:7NXW|rcsb pdb:7NXY|rcsb pdb:7NY4|rcsb pdb:7NYE|rcsb pdb:7NYF|rcsb pdb:7NYG|rcsb pdb:7NZ6|rcsb pdb:7NZG|rcsb pdb:7NZK|reactome:R-HSA-6804114|reactome:R-HSA-75035|reactome:R-HSA-9614399|refseq:NP_006133.1|dip:DIP-29861N|entrezgene/locuslink:2810(identity)	-	crc64:8E71278ED6D3A912	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Uh6OsQDXtmnLKMAEZHl/NTKCEYY559292	rogid:HI+I1sXZRxVaRy9nzl3O0HmaSSE9606	intact-crc:3F691D8361477727|rigid:tQVJ4k2Zv3BGIQUdO+iwOfZEkx8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9BSE4	uniprotkb:Q03362	intact:EBI-2868124|uniprotkb:A4D1Y8|uniprotkb:Q9H6F9|ensembl:ENSP00000310729|ensembl:ENSP00000379390	intact:EBI-2057915|uniprotkb:D6VT99|ensemblfungi:YDR476C	psi-mi:herp2_human(display_long)|uniprotkb:HERPUD2(gene name)|psi-mi:HERPUD2(display_short)	psi-mi:yd476_yeast(display_long)|uniprotkb:YDR476C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11545327|imex:IM-24995-2425	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_071768.3|refseq:XP_016867995.1|ensembl:ENSG00000122557(gene)|ensembl:ENST00000311350(transcript)|ensembl:ENST00000396081(transcript)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|interpro:IPR000626(Ubiquitin)|interpro:IPR029071|interpro:IPR039751|rcsb pdb:2KDB|entrezgene/locuslink:64224(identity)	sgd:S000002884|refseq:NP_010764.1|mint:Q03362|ensemblfungi:YDR476C(gene)|ensemblfungi:YDR476C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|sgd:YDR476C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:h4jBbYdKwKQBN6Jd3/QQA0hNOQw9606	rogid:YEqaI+xtDR2srSbbY5vQtWY+h6s559292	intact-crc:09FA3201FAE518C4|rigid:OJa1EzKTf96bXA5efxhhBZ6EO/s	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q03654	uniprotkb:Q96MT8-3	intact:EBI-476|uniprotkb:Q6B1D8|ensemblfungi:YMR213W|uniprotkb:D6W038	intact:EBI-11522539|ensembl:ENSP00000507703|ensembl:ENSP00000328382|ensembl:ENSP00000506728|ensembl:ENSP00000506791|ensembl:ENSP00000506828|ensembl:ENSP00000507228	psi-mi:cef1_yeast(display_long)|uniprotkb:CEF1(gene name)|psi-mi:CEF1(display_short)|uniprotkb:YMR213W(locus name)|uniprotkb:YM8261.07(orf name)|uniprotkb:NTC85(gene name synonym)|uniprotkb:PRP nineteen-associated complex protein 85(gene name synonym)|uniprotkb:PRP19-associated complex protein 85(gene name synonym)	psi-mi:q96mt8-3(display_long)|uniprotkb:CEP63(gene name)|psi-mi:CEP63(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11545392|imex:IM-24995-2432	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013940.1|sgd:S000004826|ensemblfungi:YMR213W(gene)|ensemblfungi:YMR213W_mRNA(transcript)|go:"GO:0000350"(generation of catalytic spliceosome for second transesterification step)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000974"(Prp19 complex)|go:"GO:0003677"(DNA binding)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017930|interpro:IPR021786|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|rcsb pdb:7DCO|dip:DIP-1113N|mint:Q03654|sgd:YMR213W(identity)	intact:EBI-741977(isoform-parent)|ensembl:ENST00000332047(transcript)|ensembl:ENST00000682042(transcript)|ensembl:ENST00000682800(transcript)|ensembl:ENST00000682858(transcript)|ensembl:ENST00000683177(transcript)|ensembl:ENST00000683861(transcript)|ensembl:ENSG00000182923(gene)|uniprotkb:Q96MT8-3(isoform-parent)|entrezgene/locuslink:80254(identity)	-	crc64:A4C417A8B330EA9C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:AsbV7RtNk+8mCzLk2wZYqbULOFg559292	rogid:U0uvVcOCzA8Qp2cCB0ilixgd4Yc9606	intact-crc:F46939785DD47EA0|rigid:M1Vh7K1UdJklmCjhPNABta8/GdY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q03654	uniprotkb:Q5JR59-3	intact:EBI-476|uniprotkb:Q6B1D8|ensemblfungi:YMR213W|uniprotkb:D6W038	intact:EBI-11522433|ensembl:ENSP00000370186	psi-mi:cef1_yeast(display_long)|uniprotkb:CEF1(gene name)|psi-mi:CEF1(display_short)|uniprotkb:YMR213W(locus name)|uniprotkb:YM8261.07(orf name)|uniprotkb:NTC85(gene name synonym)|uniprotkb:PRP nineteen-associated complex protein 85(gene name synonym)|uniprotkb:PRP19-associated complex protein 85(gene name synonym)	psi-mi:q5jr59-3(display_long)|uniprotkb:MTUS2(gene name)|psi-mi:MTUS2(display_short)|uniprotkb:CAZIP(gene name synonym)|uniprotkb:Cardiac zipper protein(gene name synonym)|uniprotkb:KIAA0774(gene name synonym)|uniprotkb:Microtubule plus-end tracking protein TIP150(gene name synonym)|uniprotkb:TIP150(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11545383|imex:IM-24995-2431	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013940.1|sgd:S000004826|ensemblfungi:YMR213W(gene)|ensemblfungi:YMR213W_mRNA(transcript)|go:"GO:0000350"(generation of catalytic spliceosome for second transesterification step)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000974"(Prp19 complex)|go:"GO:0003677"(DNA binding)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017930|interpro:IPR021786|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|rcsb pdb:7DCO|dip:DIP-1113N|mint:Q03654|sgd:YMR213W(identity)	ensembl:ENSG00000132938(gene)|ensembl:ENST00000380808(transcript)|intact:EBI-742948(isoform-parent)|uniprotkb:Q5JR59-3(isoform-parent)|entrezgene/locuslink:23281(identity)	-	crc64:A4C417A8B330EA9C	isoform-comment:No experimental confirmation available.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:AsbV7RtNk+8mCzLk2wZYqbULOFg559292	rogid:npId9tC7VoLN/jteoBiRbSYChPs9606	intact-crc:7CCFD106C3CC8445|rigid:bQMRsdSCaKABsIAcLn26s2IoIpM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q03654	uniprotkb:G5E962	intact:EBI-476|uniprotkb:Q6B1D8|ensemblfungi:YMR213W|uniprotkb:D6W038	intact:EBI-11525615|ensembl:ENSP00000328177	psi-mi:cef1_yeast(display_long)|uniprotkb:CEF1(gene name)|psi-mi:CEF1(display_short)|uniprotkb:YMR213W(locus name)|uniprotkb:YM8261.07(orf name)|uniprotkb:NTC85(gene name synonym)|uniprotkb:PRP nineteen-associated complex protein 85(gene name synonym)|uniprotkb:PRP19-associated complex protein 85(gene name synonym)	psi-mi:g5e962_human(display_long)|uniprotkb:hCG_1644200(orf name)|uniprotkb:MAGEA11(gene name)|psi-mi:MAGEA11(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11545372|imex:IM-24995-2430	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013940.1|sgd:S000004826|ensemblfungi:YMR213W(gene)|ensemblfungi:YMR213W_mRNA(transcript)|go:"GO:0000350"(generation of catalytic spliceosome for second transesterification step)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000974"(Prp19 complex)|go:"GO:0003677"(DNA binding)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017930|interpro:IPR021786|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|rcsb pdb:7DCO|dip:DIP-1113N|mint:Q03654|sgd:YMR213W(identity)	refseq:NP_001011544.1|ensembl:ENSG00000185247(gene)|ensembl:ENST00000333104(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016604"(nuclear body)|interpro:IPR002190(MAGE protein)|interpro:IPR021072|interpro:IPR030099|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|entrezgene/locuslink:4110(identity)	-	crc64:A4C417A8B330EA9C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:AsbV7RtNk+8mCzLk2wZYqbULOFg559292	rogid:sVB0aA6yibWUx/d2SE+pwpKKgtI9606	intact-crc:B4D9267AAB5E75C5|rigid:L+RpFPw6IWhOHFNjUFked8U1UUM	false	-	sufficient binding region:82-400	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q03718	uniprotkb:Q9Y6D9	intact:EBI-27756|uniprotkb:D6VZF1|ensemblfungi:YML023C	intact:EBI-742610|uniprotkb:B3KR41|uniprotkb:Q9UNH0|uniprotkb:Q13312|uniprotkb:Q75MI0|uniprotkb:Q86UM4|ensembl:ENSP00000265854|ensembl:ENSP00000382562|ensembl:ENSP00000385334	psi-mi:nse5_yeast(display_long)|uniprotkb:YML023C(locus name)|uniprotkb:NSE5(gene name)|psi-mi:NSE5(display_short)	psi-mi:md1l1_human(display_long)|uniprotkb:Mitotic arrest deficient 1-like protein 1(gene name synonym)|uniprotkb:Mitotic checkpoint MAD1 protein homolog(gene name synonym)|uniprotkb:Tax-binding protein 181(gene name synonym)|uniprotkb:MAD1L1(gene name)|psi-mi:MAD1L1(display_short)|uniprotkb:MAD1(gene name synonym)|uniprotkb:TXBP181(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11545429|imex:IM-24995-2436	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013689.1|sgd:S000004485|dip:DIP-4547N|ensemblfungi:YML023C(gene)|ensemblfungi:YML023C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0016925"(protein sumoylation)|go:"GO:0030915"(Smc5-Smc6 complex)|interpro:IPR014803(DNA repair protein Nse5)|rcsb pdb:7LTO|sgd:YML023C(identity)	refseq:NP_001013858.1|refseq:NP_001013859.1|refseq:NP_003541.2|refseq:NP_001291452.1|refseq:NP_001291453.1|ensembl:ENSG00000002822(gene)|ensembl:ENST00000265854(transcript)|go:"GO:0090235"(regulation of metaphase plate congression)|go:"GO:1902426"(deactivation of mitotic spindle assembly checkpoint)|interpro:IPR008672(Mitotic checkpoint)|mint:Q9Y6D9|rcsb pdb:1GO4|rcsb pdb:4DZO|rcsb pdb:7B1F|rcsb pdb:7B1H|rcsb pdb:7B1J|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|ensembl:ENST00000399654(transcript)|ensembl:ENST00000406869(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043515"(kinetochore binding)|go:"GO:0044615"(nuclear pore nuclear basket)|go:"GO:0048538"(thymus development)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0072686"(mitotic spindle)|refseq:XP_005249934.1|dip:DIP-29654N|entrezgene/locuslink:8379(identity)	-	crc64:6680A04D91E537DD	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:xDmbHW4E/uX4NGGcDCMXTnUDQGk559292	rogid:9CcqpZlN0IgqC939rIo7vNgOvLQ9606	intact-crc:1D3102D128BE147E|rigid:xPpbcd/v/e7dd9G01hJetUFUDS8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q03718	uniprotkb:P63279	intact:EBI-27756|uniprotkb:D6VZF1|ensemblfungi:YML023C	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	psi-mi:nse5_yeast(display_long)|uniprotkb:YML023C(locus name)|uniprotkb:NSE5(gene name)|psi-mi:NSE5(display_short)	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11545420|imex:IM-24995-2435	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013689.1|sgd:S000004485|dip:DIP-4547N|ensemblfungi:YML023C(gene)|ensemblfungi:YML023C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0016925"(protein sumoylation)|go:"GO:0030915"(Smc5-Smc6 complex)|interpro:IPR014803(DNA repair protein Nse5)|rcsb pdb:7LTO|sgd:YML023C(identity)	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N|entrezgene/locuslink:7329(identity)	-	crc64:6680A04D91E537DD	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:xDmbHW4E/uX4NGGcDCMXTnUDQGk559292	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	intact-crc:F05F0341AEFFDEC9|rigid:uLlN/Eozbz0vf94J6UEzlw91zWI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8N6L0	uniprotkb:Q03714	intact:EBI-749265|uniprotkb:Q96MC3|ensembl:ENSP00000404220	intact:EBI-27760|uniprotkb:D6VZE5|ensemblfungi:YML029W	psi-mi:kash5_human(display_long)|uniprotkb:KASH5(gene name)|psi-mi:KASH5(display_short)|uniprotkb:CCDC155(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 155(gene name synonym)|uniprotkb:KASH domain-containing protein 5(gene name synonym)	psi-mi:usa1_yeast(display_long)|uniprotkb:USA1(gene name)|psi-mi:USA1(display_short)|uniprotkb:YML029W(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11545411|imex:IM-24995-2434	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_653289.3|ensembl:ENSG00000161609(gene)|ensembl:ENST00000447857(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034397"(telomere localization)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051225"(spindle assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0090172"(microtubule cytoskeleton organization involved in homologous chromosome segregation)|go:"GO:0090220"(chromosome localization to nuclear envelope involved in homologous chromosome segregation)|go:"GO:0090619"(meiotic spindle pole)|interpro:IPR011992(EF-Hand type)|interpro:IPR028168|interpro:IPR028170|interpro:IPR039508|mint:Q8N6L0|rcsb pdb:6R2I|rcsb pdb:6WMF|entrezgene/locuslink:147872(identity)	refseq:NP_013683.1|sgd:S000004491|dip:DIP-6423N|mint:Q03714|ensemblfungi:YML029W(gene)|ensemblfungi:YML029W_mRNA(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:1902499"(positive regulation of protein autoubiquitination)|interpro:IPR000626(Ubiquitin)|interpro:IPR029071|rcsb pdb:6VJZ|rcsb pdb:6VK0|sgd:YML029W(identity)	-	-	crc64:9B93ECA6C5421FD6	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Wl9L7AcvDHCZuKjYLn8QgGIbZTc9606	rogid:k5/W6R8NnkOWchVSQSoXCbvaAZ8559292	intact-crc:6E7DAB49FC6A0C85|rigid:CfZ0q15whvyngzr6nXKsflD12lg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96BA8	uniprotkb:Q03697	intact:EBI-6942903|ensembl:ENSP00000481956|intact:MINT-268046|intact:MINT-8162577|uniprotkb:Q8N2D5|uniprotkb:Q96CP0	intact:EBI-27776|uniprotkb:D6VZD7|ensemblfungi:YML038C	psi-mi:cr3l1_human(display_long)|uniprotkb:CREB3L1(gene name)|psi-mi:CREB3L1(display_short)|uniprotkb:OASIS(gene name synonym)|uniprotkb:PSEC0238(orf name)|uniprotkb:Old astrocyte specifically-induced substance(gene name synonym)	psi-mi:ymd8_yeast(display_long)|uniprotkb:YML038C(locus name)|uniprotkb:YMD8(gene name)|psi-mi:YMD8(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11545401|imex:IM-24995-2433	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157613(gene)|ensembl:ENST00000621158(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0070278"(extracellular matrix constituent secretion)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029805|mint:Q96BA8|reactome:R-HSA-8874211|refseq:NP_443086.1|entrezgene/locuslink:90993(identity)	refseq:NP_013674.1|sgd:S000004502|dip:DIP-1312N|mint:Q03697|ensemblfungi:YML038C(gene)|ensemblfungi:YML038C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005338"(nucleotide-sugar transmembrane transporter activity)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0008643"(carbohydrate transport)|go:"GO:0015297"(antiporter activity)|go:"GO:0015780"(nucleotide-sugar transmembrane transport)|go:"GO:0015786"(UDP-glucose transmembrane transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030663"(COPI-coated vesicle membrane)|interpro:IPR004853(Protein of unknown function DUF250)|sgd:YML038C(identity)	-	comment:mint|function:"Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE"	crc64:37A03543D3AB695E	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:sMWUFmBeBBCO+T0Y2CuB/un1lBg9606	rogid:i2Fqb84s31vBiayw4lJW8o3S3WU559292	intact-crc:50FC9F16A9505558|rigid:QWAjWChgf4EUv0/21VdKrY0yHr4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q03860	uniprotkb:Q8N6L0	intact:EBI-37537|uniprotkb:D6VS87|ensemblfungi:YDR100W	intact:EBI-749265|uniprotkb:Q96MC3|ensembl:ENSP00000404220	psi-mi:tvp15_yeast(display_long)|uniprotkb:YDR100W(locus name)|uniprotkb:TVP15(gene name)|psi-mi:TVP15(display_short)|uniprotkb:TLG2 compartment vesicle protein 15(gene name synonym)|uniprotkb:TLG2-vesicle protein of 15 kDa(gene name synonym)	psi-mi:kash5_human(display_long)|uniprotkb:KASH5(gene name)|psi-mi:KASH5(display_short)|uniprotkb:CCDC155(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 155(gene name synonym)|uniprotkb:KASH domain-containing protein 5(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11545474|imex:IM-24995-2441	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002507|refseq:NP_010385.3|dip:DIP-2049N|mint:Q03860|ensemblfungi:YDR100W(gene)|ensemblfungi:YDR100W_mRNA(transcript)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0042802"(identical protein binding)|interpro:IPR013714(COPI associated)|sgd:YDR100W(identity)	refseq:NP_653289.3|ensembl:ENSG00000161609(gene)|ensembl:ENST00000447857(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034397"(telomere localization)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051225"(spindle assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0090172"(microtubule cytoskeleton organization involved in homologous chromosome segregation)|go:"GO:0090220"(chromosome localization to nuclear envelope involved in homologous chromosome segregation)|go:"GO:0090619"(meiotic spindle pole)|interpro:IPR011992(EF-Hand type)|interpro:IPR028168|interpro:IPR028170|interpro:IPR039508|mint:Q8N6L0|rcsb pdb:6R2I|rcsb pdb:6WMF|entrezgene/locuslink:147872(identity)	-	crc64:395F700FBB14C569	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:WUrBFK6BrbdV4tMhayDYqINQ5FM559292	rogid:Wl9L7AcvDHCZuKjYLn8QgGIbZTc9606	intact-crc:1A27D5A8112DE66F|rigid:fuv98/dOVC/xa5CEB2tu0K6VsSg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9NYB9-2	uniprotkb:Q03782	intact:EBI-11096309|ensembl:ENSP00000261017	intact:EBI-627|uniprotkb:D6VSM1|ensemblfungi:YDR240C	psi-mi:q9nyb9-2(display_long)|uniprotkb:ABI2(gene name)|psi-mi:ABI2(display_short)|uniprotkb:ARGBPIA(gene name synonym)|uniprotkb:Abelson interactor 2(gene name synonym)|uniprotkb:Abl-binding protein 3(gene name synonym)|uniprotkb:Arg-binding protein 1(gene name synonym)	psi-mi:snu56_yeast(display_long)|uniprotkb:YDR240C(locus name)|uniprotkb:SNU56(gene name)|psi-mi:SNU56(display_short)|uniprotkb:MUD10(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11545465|imex:IM-24995-2440	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-743598(isoform-parent)|ensembl:ENSG00000138443(gene)|ensembl:ENST00000261017(transcript)|uniprotkb:Q9NYB9-2(isoform-parent)|entrezgene/locuslink:10152(identity)	sgd:S000002648|refseq:NP_010526.1|dip:DIP-6514N|mint:Q03782|ensemblfungi:YDR240C(gene)|ensemblfungi:YDR240C_mRNA(transcript)|go:"GO:0000243"(commitment complex)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005685"(U1 snRNP)|go:"GO:0071004"(U2-type prespliceosome)|interpro:IPR043954|rcsb pdb:5ZWN|rcsb pdb:6G90|rcsb pdb:6N7P|rcsb pdb:6N7R|rcsb pdb:6N7X|sgd:YDR240C(identity)	-	-	crc64:5E0C7A1FD577808F	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:VNi9aUeavD8+CCi+n1DXS+7mmbs9606	rogid:gz3aUh/8pFF7Yn8XS9gdhSWrVNs559292	intact-crc:90C12264AD031CC8|rigid:9EPgDys2FUgB+pXASx5eV7k66h4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q03782	uniprotkb:P43355	intact:EBI-627|uniprotkb:D6VSM1|ensemblfungi:YDR240C	intact:EBI-740978|ensembl:ENSP00000349085|uniprotkb:O00346|uniprotkb:B2RC81	psi-mi:snu56_yeast(display_long)|uniprotkb:YDR240C(locus name)|uniprotkb:SNU56(gene name)|psi-mi:SNU56(display_short)|uniprotkb:MUD10(gene name synonym)	psi-mi:maga1_human(display_long)|uniprotkb:MAGE-1 antigen(gene name synonym)|uniprotkb:Antigen MZ2-E(gene name synonym)|uniprotkb:Cancer/testis antigen 1.1(gene name synonym)|uniprotkb:MAGEA1(gene name)|psi-mi:MAGEA1(display_short)|uniprotkb:MAGE1(gene name synonym)|uniprotkb:MAGE1A(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11545456|imex:IM-24995-2439	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002648|refseq:NP_010526.1|dip:DIP-6514N|mint:Q03782|ensemblfungi:YDR240C(gene)|ensemblfungi:YDR240C_mRNA(transcript)|go:"GO:0000243"(commitment complex)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005685"(U1 snRNP)|go:"GO:0071004"(U2-type prespliceosome)|interpro:IPR043954|rcsb pdb:5ZWN|rcsb pdb:6G90|rcsb pdb:6N7P|rcsb pdb:6N7R|rcsb pdb:6N7X|sgd:YDR240C(identity)	refseq:NP_004979.3|ensembl:ENSG00000198681(gene)|ensembl:ENST00000356661(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|interpro:IPR002190(MAGE protein)|interpro:IPR021072|interpro:IPR030093|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|rcsb pdb:1W72|rcsb pdb:3BO8|dip:DIP-54794N|entrezgene/locuslink:4100(identity)	-	crc64:5E0C7A1FD577808F	crc64:544EEB1F9F4E9D33	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:gz3aUh/8pFF7Yn8XS9gdhSWrVNs559292	rogid:6XW3mnTNM3yvOtXmiFbU8Uz3hjA9606	intact-crc:5577CD58EADDF678|rigid:mWzhpwpq6fEPBATJay05BGCidGM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96AA8	uniprotkb:Q03768	intact:EBI-752007|uniprotkb:O60302|uniprotkb:B4DSG0|uniprotkb:A4ZZA7|uniprotkb:Q548S1|uniprotkb:A8K5G5|uniprotkb:G5E9Y0|ensembl:ENSP00000265272	intact:EBI-7618|uniprotkb:D6VSD4|ensemblfungi:YDR152W	psi-mi:jkip2_human(display_long)|uniprotkb:JAMIP2(gene name synonym)|uniprotkb:NECC1(gene name synonym)|uniprotkb:Neuroendocrine long coiled-coil protein 1(gene name synonym)|uniprotkb:CTCL tumor antigen HD-CL-04(gene name synonym)|uniprotkb:JAKMIP2(gene name)|psi-mi:JAKMIP2(display_short)|uniprotkb:KIAA0555(gene name synonym)	psi-mi:gir2_yeast(display_long)|uniprotkb:GIR2(gene name)|psi-mi:GIR2(display_short)|uniprotkb:YDR152W(locus name)|uniprotkb:YD8358.08(orf name)|uniprotkb:DFRP2(gene name synonym)|uniprotkb:DRG family-regulatory protein 2(gene name synonym)|uniprotkb:Genetically interacts with ribosomal genes protein 2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11545447|imex:IM-24995-2438	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055605.2|refseq:NP_001257870.1|refseq:NP_001257863.1|refseq:NP_001269211.1|refseq:XP_016865586.1|ensembl:ENSG00000176049(gene)|ensembl:ENST00000265272(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0008017"(microtubule binding)|go:"GO:0019900"(kinase binding)|interpro:IPR024836|interpro:IPR031994|entrezgene/locuslink:9832(identity)	sgd:S000002559|refseq:NP_010436.3|mint:Q03768|dip:DIP-1751N|ensemblfungi:YDR152W(gene)|ensemblfungi:YDR152W_mRNA(transcript)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005844"(polysome)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:1903833"(positive regulation of cellular response to amino acid starvation)|interpro:IPR006575(RWD)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR040213|sgd:YDR152W(identity)	-	-	crc64:CE09A067388638ED	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:WnaHkeDBQXut9F9AzzaCrDYpmAE9606	rogid:2gb8Bf2IGl8RoOmNcIvEMlmgeTE559292	intact-crc:DD13B98B26E365F7|rigid:f3XZjsvsBmJONZLjVfhud9qGzeo	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q03759	uniprotkb:Q5JST6	intact:EBI-27937|uniprotkb:D6W0H6|ensemblfungi:YML108W	intact:EBI-2349927|uniprotkb:Q9H653|uniprotkb:Q5JST8|uniprotkb:Q68DK4|uniprotkb:Q8NEI0|intact:EBI-28971886|ensembl:ENSP00000404232	psi-mi:ymk8_yeast(display_long)|uniprotkb:YM8339.11(orf name)|uniprotkb:YML108W(locus name)	psi-mi:efhc2_human(display_long)|uniprotkb:EFHC2(gene name)|psi-mi:EFHC2(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11545438|imex:IM-24995-2437	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013599.1|sgd:S000004576|dip:DIP-3849N|ensemblfungi:YML108W(gene)|ensemblfungi:YML108W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|interpro:IPR015080(Protein of unknown function DUF1892)|interpro:IPR035946|rcsb pdb:1N6Z|sgd:YML108W(identity)	ensembl:ENSP00000404232|refseq:NP_079460.2|ensembl:ENSG00000183690(gene)|ensembl:ENST00000420999(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005930"(axoneme)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0060285"(cilium-dependent cell motility)|go:"GO:0072686"(mitotic spindle)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR006602(Region of unknown function DM10)|interpro:IPR011992(EF-Hand type)|interpro:IPR040193|rcsb pdb:2Z13|rcsb pdb:2Z14|entrezgene/locuslink:80258(identity)	-	crc64:8D07986085C369C4	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:SLeZv2kwwNuEtzk4nFkrHoP4HOo559292	rogid:O1XriQSkLcYkk7H7AlanQ1FKIBY9606	intact-crc:835457DCC6284F52|rigid:5cqc0lY4K7kuTXTQS+ghLIml7NU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q03973	uniprotkb:Q0VDD7	intact:EBI-33047|uniprotkb:D6VSF6|ensemblfungi:YDR174W	intact:EBI-741210|ensembl:ENSP00000465822|ensembl:ENSP00000500215|uniprotkb:Q13411|uniprotkb:Q8N825|uniprotkb:Q96D63|uniprotkb:Q9BU49	psi-mi:hmo1_yeast(display_long)|uniprotkb:HMO1(gene name)|psi-mi:HMO1(display_short)|uniprotkb:High spontaneous mutagenesis protein 2(gene name synonym)|uniprotkb:HSM2(gene name synonym)|uniprotkb:YD9395.07(orf name)|uniprotkb:YDR174W(locus name)	psi-mi:brme1_human(display_long)|uniprotkb:BRME1(gene name)|psi-mi:BRME1(display_short)|uniprotkb:C19orf57(gene name synonym)|uniprotkb:Pre-T/NK cell-associated protein 3B3(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11545501|imex:IM-24995-2444	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010459.1|sgd:S000002581|mint:Q03973|dip:DIP-1687N|ensemblfungi:YDR174W(gene)|ensemblfungi:YDR174W_mRNA(transcript)|go:"GO:0000400"(four-way junction DNA binding)|go:"GO:0001174"(transcriptional start site selection at RNA polymerase II promoter)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006265"(DNA topological change)|go:"GO:0006323"(DNA packaging)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006356"(regulation of transcription by RNA polymerase I)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0030261"(chromosome condensation)|go:"GO:0032040"(small-subunit processome)|go:"GO:0033553"(rDNA heterochromatin)|go:"GO:0044804"(autophagy of nucleus)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0060962"(regulation of ribosomal protein gene transcription by RNA polymerase II)|go:"GO:0070550"(rDNA condensation)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR036910|reactome:R-SCE-140342|reactome:R-SCE-5620971|reactome:R-SCE-5686938|reactome:R-SCE-6798695|sgd:YDR174W(identity)	refseq:NP_077299.3|ensembl:ENSG00000132016(gene)|ensembl:ENSG00000288152(gene)|ensembl:ENST00000586783(transcript)|ensembl:ENST00000672170(transcript)|go:"GO:0005694"(chromosome)|go:"GO:0007144"(female meiosis I)|go:"GO:0007275"(multicellular organism development)|go:"GO:0007283"(spermatogenesis)|go:"GO:1990918"(double-strand break repair involved in meiotic recombination)|interpro:IPR031441|refseq:NP_001332773.1|entrezgene/locuslink:79173(identity)	-	crc64:3D6DCD56A28B7D77	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:9sHGPuUbReXRmvQYqKvnd4fWBd4559292	rogid:YUbAjs5ZmWOPWRA9kq5qRZRioR49606	intact-crc:3B2EF09DD9A57A68|rigid:mqvSRvkWXmonNANRgMPSVNi47EY	false	-	sufficient binding region:336-668	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q03920	uniprotkb:Q9BUY5	intact:EBI-31378|uniprotkb:D6VSC3|ensemblfungi:YDR140W	intact:EBI-743265|ensembl:ENSP00000253115|ensembl:ENSP00000439017|uniprotkb:B3KTL2	psi-mi:mtq2_yeast(display_long)|uniprotkb:MTQ2(gene name)|psi-mi:MTQ2(display_short)|uniprotkb:MTC6(gene name synonym)|uniprotkb:"N(5)-glutamine methyltransferase MTQ2"(gene name synonym)|uniprotkb:YDR140W(locus name)	psi-mi:zn426_human(display_long)|uniprotkb:ZNF426(gene name)|psi-mi:ZNF426(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11545492|imex:IM-24995-2443	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010424.3|sgd:S000002547|dip:DIP-1755N|mint:Q03920|ensemblfungi:YDR140W(gene)|ensemblfungi:YDR140W_mRNA(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006417"(regulation of translation)|go:"GO:0008276"(protein methyltransferase activity)|go:"GO:0008757"(S-adenosylmethionine-dependent methyltransferase activity)|go:"GO:0018364"(peptidyl-glutamine methylation)|go:"GO:0035657"(eRF1 methyltransferase complex)|go:"GO:0102559"("protein-(glutamine-N5) methyltransferase activity")|interpro:IPR002052(N-6 adenine-specific DNA methylase, conserved site)|interpro:IPR004557(Putative methylase)|interpro:IPR007848(Methyltransferase small)|interpro:IPR029063|reactome:R-SCE-156581|reactome:R-SCE-72764|sgd:YDR140W(identity)	refseq:NP_077011.1|ensembl:ENSG00000130818(gene)|ensembl:ENST00000253115(transcript)|ensembl:ENST00000535489(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|refseq:NP_001304984.1|refseq:NP_001304985.1|entrezgene/locuslink:79088(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:pu/ERTe9ojnsy8nxRKkRA+sHq80559292	rogid:QPI15/Fod+FtlArvKKNMPGSu3zQ9606	intact-crc:E2693FD0C116C104|rigid:XdZxrTaU/RWJjyUcL48LBOGZOr8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q03920	uniprotkb:O43186	intact:EBI-31378|uniprotkb:D6VSC3|ensemblfungi:YDR140W	intact:EBI-748171|uniprotkb:Q0QD45|ensembl:ENSP00000221996|ensembl:ENSP00000445565	psi-mi:mtq2_yeast(display_long)|uniprotkb:MTQ2(gene name)|psi-mi:MTQ2(display_short)|uniprotkb:MTC6(gene name synonym)|uniprotkb:"N(5)-glutamine methyltransferase MTQ2"(gene name synonym)|uniprotkb:YDR140W(locus name)	psi-mi:crx_human(display_long)|uniprotkb:CRX(gene name)|psi-mi:CRX(display_short)|uniprotkb:CORD2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11545483|imex:IM-24995-2442	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010424.3|sgd:S000002547|dip:DIP-1755N|mint:Q03920|ensemblfungi:YDR140W(gene)|ensemblfungi:YDR140W_mRNA(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006417"(regulation of translation)|go:"GO:0008276"(protein methyltransferase activity)|go:"GO:0008757"(S-adenosylmethionine-dependent methyltransferase activity)|go:"GO:0018364"(peptidyl-glutamine methylation)|go:"GO:0035657"(eRF1 methyltransferase complex)|go:"GO:0102559"("protein-(glutamine-N5) methyltransferase activity")|interpro:IPR002052(N-6 adenine-specific DNA methylase, conserved site)|interpro:IPR004557(Putative methylase)|interpro:IPR007848(Methyltransferase small)|interpro:IPR029063|reactome:R-SCE-156581|reactome:R-SCE-72764|sgd:YDR140W(identity)	refseq:NP_000545.1|ensembl:ENSG00000105392(gene)|ensembl:ENST00000221996(transcript)|ensembl:ENST00000539067(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007601"(visual perception)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050896"(response to stimulus)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013851(Transcription factor Otx, C-terminal)|interpro:IPR017970|entrezgene/locuslink:1406(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:pu/ERTe9ojnsy8nxRKkRA+sHq80559292	rogid:v/bkO/0iLzq1Q2HtieWQQ40RF9M9606	intact-crc:51D8A1BC66EAB6CD|rigid:jK1E8/cYJFzaXPokj4t5pjA2Fhg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q04201	uniprotkb:O43765	intact:EBI-27928|uniprotkb:D6W0I3|ensemblfungi:YML101C	intact:EBI-347996|ensembl:ENSP00000221566|ensembl:ENSP00000503397|ensembl:ENSP00000504495|uniprotkb:Q9BTZ9|intact:EBI-1045243|uniprotkb:Q6FIA9|uniprotkb:D6W610	psi-mi:cue4_yeast(display_long)|uniprotkb:YML101C(locus name)|uniprotkb:Coupling of ubiquitin conjugation to ER degradation protein 4(gene name synonym)|uniprotkb:CUE4(gene name)|psi-mi:CUE4(display_short)	psi-mi:sgta_human(display_long)|uniprotkb:SGTA(gene name)|psi-mi:SGTA(display_short)|uniprotkb:SGT(gene name synonym)|uniprotkb:Alpha-SGT(gene name synonym)|uniprotkb:Vpu-binding protein(gene name synonym)|uniprotkb:SGT1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11545548|imex:IM-24995-2449	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013607.1|sgd:S000004568|dip:DIP-4525N|mint:Q04201|ensemblfungi:YML101C(gene)|ensemblfungi:YML101C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR003892(Ubiquitin system component Cue)|sgd:YML101C(identity)	rcsb pdb:4CPG|rcsb pdb:4GOD|rcsb pdb:4GOE|rcsb pdb:4GOF|reactome:R-HSA-9609523|rcsb pdb:2VYI|ensembl:ENSG00000104969(gene)|ensembl:ENST00000221566(transcript)|ensembl:ENST00000676943(transcript)|ensembl:ENST00000677149(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072380"(TRC complex)|go:"GO:0098850"(extrinsic component of synaptic vesicle membrane)|go:"GO:1903070"(negative regulation of ER-associated ubiquitin-dependent protein catabolic process)|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)|go:"GO:1903646"(positive regulation of chaperone-mediated protein folding)|go:"GO:1904288"(BAT3 complex binding)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR032374|mint:O43765|refseq:XP_011526480.1|refseq:NP_003012.1|entrezgene/locuslink:6449(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:NMBJHZbX4/gU01fk4evPDXm/M6w559292	rogid:r/Cyj4UJk/cS8QdrbjhTZMPCigI9606	intact-crc:E3EA29D9F9C35617|rigid:lkUYU9YQdUZyJS+qFXE4avLypoQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96EV8	uniprotkb:Q04110	intact:EBI-465804|uniprotkb:Q5THY3|uniprotkb:Q5THY4|uniprotkb:Q96NV2|intact:EBI-28986386|ensembl:ENSP00000341680|uniprotkb:Q9H0U2|uniprotkb:Q9H3J5|uniprotkb:A8K3V3	intact:EBI-37150|uniprotkb:D6VT71|ensemblfungi:YDR446W	psi-mi:dtbp1_human(display_long)|uniprotkb:My031(orf name)|uniprotkb:DTNBP1(gene name)|psi-mi:DTNBP1(display_short)|uniprotkb:Dystrobrevin-binding protein 1(gene name synonym)|uniprotkb:Hermansky-Pudlak syndrome 7 protein(gene name synonym)|uniprotkb:Dysbindin-1(gene name synonym)|uniprotkb:BLOC1S8(gene name synonym)|uniprotkb:Biogenesis of lysosome-related organelles complex 1 subunit 8(gene name synonym)	psi-mi:ecm11_yeast(display_long)|uniprotkb:ECM11(gene name)|psi-mi:ECM11(display_short)|uniprotkb:YDR446W(locus name)|uniprotkb:D9461.31(orf name)|uniprotkb:Extracellular mutant protein 11(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11545539|imex:IM-24995-2448	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000047579(gene)|ensembl:ENST00000344537(transcript)|go:"GO:0001956"(positive regulation of neurotransmitter secretion)|go:"GO:0005634"(nucleus)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007596"(blood coagulation)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014059"(regulation of dopamine secretion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016528"(sarcoplasm)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0030496"(midbody)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032438"(melanosome organization)|go:"GO:0033162"(melanosome membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0043005"(neuron projection)|go:"GO:0043197"(dendritic spine)|go:"GO:0005737"(cytoplasm)|go:"GO:0043506"(regulation of JUN kinase activity)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0060155"(platelet dense granule organization)|go:"GO:0060159"(regulation of dopamine receptor signaling pathway)|go:"GO:0071901"(negative regulation of protein serine/threonine kinase activity)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR007531(Dysbindin)|reactome:R-HSA-432722|go:"GO:0048490"(anterograde synaptic vesicle transport)|refseq:NP_115498.2|refseq:NP_898861.1|refseq:NP_001258597.1|refseq:NP_001258598.1|ensembl:ENST00000338950|ensembl:ENSP00000344718|ensembl:ENSP00000341680|refseq:NP_001258596.1|entrezgene/locuslink:84062(identity)	sgd:S000002854|refseq:NP_010734.1|dip:DIP-2060N|ensemblfungi:YDR446W(gene)|ensemblfungi:YDR446W_mRNA(transcript)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0005634"(nucleus)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0070193"(synaptonemal complex organization)|go:"GO:0071555"(cell wall organization)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|interpro:IPR029178|sgd:YDR446W(identity)	-	-	crc64:CB6890F4EE069232	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:PBwxp1vobm9l5yGoqev97lzkMHg9606	rogid:F5ueMuYv+ymWlt2junW3o49OB/g559292	intact-crc:55CEFA5D75B17BB7|rigid:eqNiwv+OLd0YenZ8twdCDnpnE6U	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q04110	uniprotkb:P63279	intact:EBI-37150|uniprotkb:D6VT71|ensemblfungi:YDR446W	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	psi-mi:ecm11_yeast(display_long)|uniprotkb:ECM11(gene name)|psi-mi:ECM11(display_short)|uniprotkb:YDR446W(locus name)|uniprotkb:D9461.31(orf name)|uniprotkb:Extracellular mutant protein 11(gene name synonym)	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11545530|imex:IM-24995-2447	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002854|refseq:NP_010734.1|dip:DIP-2060N|ensemblfungi:YDR446W(gene)|ensemblfungi:YDR446W_mRNA(transcript)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0005634"(nucleus)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0070193"(synaptonemal complex organization)|go:"GO:0071555"(cell wall organization)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|interpro:IPR029178|sgd:YDR446W(identity)	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N|entrezgene/locuslink:7329(identity)	-	crc64:CB6890F4EE069232	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:F5ueMuYv+ymWlt2junW3o49OB/g559292	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	intact-crc:6FB471DCCDD7BFB7|rigid:PbVxpQjOy6uwNdh04tE2X2XI63A	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q5JST6	uniprotkb:Q04087	intact:EBI-2349927|uniprotkb:Q9H653|uniprotkb:Q5JST8|uniprotkb:Q68DK4|uniprotkb:Q8NEI0|intact:EBI-28971886|ensembl:ENSP00000404232	intact:EBI-32189|uniprotkb:D6VT66|ensemblfungi:YDR439W	psi-mi:efhc2_human(display_long)|uniprotkb:EFHC2(gene name)|psi-mi:EFHC2(display_short)	psi-mi:lrs4_yeast(display_long)|uniprotkb:Loss of rDNA silencing protein 4(gene name synonym)|uniprotkb:LRS4(gene name)|psi-mi:LRS4(display_short)|uniprotkb:D9461.25(orf name)|uniprotkb:YDR439W(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11545521|imex:IM-24995-2446	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000404232|refseq:NP_079460.2|ensembl:ENSG00000183690(gene)|ensembl:ENST00000420999(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005930"(axoneme)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0060285"(cilium-dependent cell motility)|go:"GO:0072686"(mitotic spindle)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR006602(Region of unknown function DM10)|interpro:IPR011992(EF-Hand type)|interpro:IPR040193|rcsb pdb:2Z13|rcsb pdb:2Z14|entrezgene/locuslink:80258(identity)	refseq:NP_010727.1|sgd:S000002847|dip:DIP-1416N|mint:Q04087|ensemblfungi:YDR439W(gene)|ensemblfungi:YDR439W_mRNA(transcript)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0033551"(monopolin complex)|go:"GO:0034503"(protein localization to nucleolar rDNA repeats)|go:"GO:0045143"(homologous chromosome segregation)|go:"GO:0051455"(monopolar spindle attachment to meiosis I kinetochore)|go:"GO:0070550"(rDNA condensation)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|interpro:IPR018479|rcsb pdb:3N7N|sgd:YDR439W(identity)	-	-	crc64:60D880BA947B9005	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:O1XriQSkLcYkk7H7AlanQ1FKIBY9606	rogid:XJ/t2ftZBXOTJshr/zQeMxci/6Q559292	intact-crc:4B3947AD24EC5981|rigid:G9MVygKpQUyOlAlbHk3FtZJ1nVc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P43356	uniprotkb:Q03981	intact:EBI-5650739|uniprotkb:A8K328|uniprotkb:Q32NC6|ensembl:ENSP00000333487|ensembl:ENSP00000359316|ensembl:ENSP00000469919|ensembl:ENSP00000470872|ensembl:ENSP00000480491|ensembl:ENSP00000480738|ensembl:ENSP00000484290|ensembl:ENSP00000485391|ensembl:ENSP00000485541|ensembl:ENSP00000507594|ensembl:ENSP00000507899	intact:EBI-33535|uniprotkb:D6VSG1|ensemblfungi:YDR179C	psi-mi:maga2_human(display_long)|uniprotkb:MAGEA2(gene name)|psi-mi:MAGEA2(display_short)|uniprotkb:MAGEA2B(gene name)|psi-mi:MAGEA2B(display_short)|uniprotkb:MAGE2(gene name synonym)|uniprotkb:MAGEA2A(gene name synonym)|uniprotkb:MAGE2(gene name synonym)|uniprotkb:MAGEA2(gene name synonym)|uniprotkb:Cancer/testis antigen 1.2(gene name synonym)|uniprotkb:MAGE-2 antigen(gene name synonym)	psi-mi:csn9_yeast(display_long)|uniprotkb:CSN9(gene name)|psi-mi:CSN9(display_short)|uniprotkb:YDR179C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11545512|imex:IM-24995-2445	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001269430.1|refseq:NP_001269431.1|refseq:NP_001269433.1|refseq:NP_001269434.1|refseq:NP_001308329.1|refseq:NP_001308330.1|refseq:NP_001308331.1|refseq:NP_001308332.1|refseq:NP_001308333.1|refseq:NP_005352.1|refseq:NP_705692.1|refseq:NP_786884.1|refseq:NP_786885.1|dip:DIP-61231N|refseq:XP_016884895.1|refseq:XP_016885008.1|ensembl:ENSG00000183305(gene)|ensembl:ENSG00000268606(gene)|ensembl:ENST00000331220(transcript)|ensembl:ENST00000370293(transcript)|ensembl:ENST00000595583(transcript)|ensembl:ENST00000598543(transcript)|ensembl:ENST00000611557(transcript)|ensembl:ENST00000611674(transcript)|ensembl:ENST00000620710(transcript)|ensembl:ENST00000623438(transcript)|ensembl:ENST00000623806(transcript)|ensembl:ENST00000682532(transcript)|ensembl:ENST00000684311(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0016605"(PML body)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0033234"(negative regulation of protein sumoylation)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0044257"(cellular protein catabolic process)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0072331"(signal transduction by p53 class mediator)|go:"GO:0090398"(cellular senescence)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901984"(negative regulation of protein acetylation)|interpro:IPR002190(MAGE protein)|interpro:IPR021072|interpro:IPR030103|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|entrezgene/locuslink:266740(identity)	refseq:NP_010464.1|sgd:S000002586|mint:Q03981|dip:DIP-1580N|ensemblfungi:YDR179C(gene)|ensemblfungi:YDR179C_mRNA(transcript)|go:"GO:0000338"(protein deneddylation)|go:"GO:0000754"(adaptation of signaling pathway by response to pheromone involved in conjugation with cellular fusion)|go:"GO:0005737"(cytoplasm)|go:"GO:0008180"(COP9 signalosome)|interpro:IPR016806(COP9 signalosome complex, subunit 9)|sgd:YDR179C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:aYv4+irEk9vGE2f3yZQR8hCQGec9606	rogid:DHoL1YAXDCBQU4RcLn9kg4T00V0559292	intact-crc:706474714A19FA02|rigid:DwZKi1PtUD53+blnRvAz8zMYZxk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96H20	uniprotkb:Q04272	intact:EBI-747719|uniprotkb:Q8IXY3|uniprotkb:Q9UN50|ensembl:ENSP00000421380	intact:EBI-28157|uniprotkb:D6VZQ1|ensemblfungi:YMR077C	psi-mi:snf8_human(display_long)|uniprotkb:ELL-associated protein of 30 kDa(gene name synonym)|uniprotkb:SNF8(gene name)|psi-mi:SNF8(display_short)|uniprotkb:EAP30(gene name synonym)|uniprotkb:ESCRT-II complex subunit VPS22(gene name synonym)	psi-mi:vps20_yeast(display_long)|uniprotkb:ASI10(gene name synonym)|uniprotkb:CHM6(gene name synonym)|uniprotkb:VPT20(gene name synonym)|uniprotkb:YM9582.02C(orf name)|uniprotkb:YMR077C(locus name)|uniprotkb:VPS20(gene name)|psi-mi:VPS20(display_short)|uniprotkb:Vacuolar protein-targeting protein 20(gene name synonym)|uniprotkb:Amino acid sensor-independent protein 10(gene name synonym)|uniprotkb:Charged multivesicular body protein 6(gene name synonym)|uniprotkb:ESCRT-III complex subunit VPS20(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11545584|imex:IM-24995-2453	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009172.2|refseq:NP_001304121.1|refseq:NP_001304122.1|refseq:NP_001304123.1|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010008"(endosome membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0016247"(channel regulator activity)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043328"(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055037"(recycling endosome)|go:"GO:0061635"(regulation of protein complex stability)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071985"(multivesicular body sorting pathway)|go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:1903772"(regulation of viral budding via host ESCRT complex)|interpro:IPR016689(ESCRT-2 complex, Snf8)|interpro:IPR036388|interpro:IPR036390|interpro:IPR040608|mint:Q96H20|rcsb pdb:2ZME|rcsb pdb:3CUQ|reactome:R-HSA-917729|reactome:R-HSA-9610379|ensembl:ENSG00000159210(gene)|ensembl:ENST00000502492(transcript)|go:"GO:0000814"(ESCRT II complex)|entrezgene/locuslink:11267(identity)	reactome:R-SCE-1632852|refseq:NP_013794.1|sgd:S000004682|dip:DIP-1961N|reactome:R-SCE-917729|reactome:R-SCE-9668328|ensemblfungi:YMR077C(gene)|ensemblfungi:YMR077C_mRNA(transcript)|go:"GO:0000815"(ESCRT III complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005771"(multivesicular body)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0015031"(protein transport)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0070676"(intralumenal vesicle formation)|go:"GO:1904669"(ATP export)|interpro:IPR005024(Snf7)|rcsb pdb:5FVL|sgd:YMR077C(identity)	-	-	crc64:CDC88BC4ADA3D602	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:FyjlBpOt9okBFV8Z+g8YLUeyCm49606	rogid:K6P+RVrruRMbHsMdRoH/v0f+0Z0559292	intact-crc:5979E0C95459E0DF|rigid:Z6nSM53uGs9aFz1mYDvVCNl7R4w	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9P1Z2	uniprotkb:Q04264	intact:EBI-749920|uniprotkb:B3KVA8|uniprotkb:Q6FI59|uniprotkb:Q71RC3|uniprotkb:Q86WF8|uniprotkb:Q96JU3|uniprotkb:Q9H090|intact:EBI-2558801|ensembl:ENSP00000449960	intact:EBI-13077|uniprotkb:Q04780|uniprotkb:D6VZQ0|ensemblfungi:YMR076C	psi-mi:caco1_human(display_long)|uniprotkb:CALCOCO1(gene name)|psi-mi:CALCOCO1(display_short)|uniprotkb:KIAA1536(gene name synonym)|uniprotkb:Calphoglin(gene name synonym)|uniprotkb:Sarcoma antigen NY-SAR-3(gene name synonym)|uniprotkb:Coiled-coil coactivator protein(gene name synonym)|uniprotkb:PP13275(orf name)|uniprotkb:UNQ2436/PRO4996(orf name)	psi-mi:pds5_yeast(display_long)|uniprotkb:PDS5(gene name)|psi-mi:PDS5(display_short)|uniprotkb:YMR076C(locus name)|uniprotkb:YM9916.15C(orf name)|uniprotkb:YM9582.01C(orf name)|uniprotkb:Precocious dissociation of sisters protein 5(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11545575|imex:IM-24995-2452	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001137154.1|refseq:NP_065949.1|refseq:XP_016875196.1|dip:DIP-47322N|ensembl:ENSG00000012822(gene)|ensembl:ENST00000550804(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0007165"(signal transduction)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0070016"(armadillo repeat domain binding)|interpro:IPR012852(Coiled-coil transcriptional coactivator-like)|interpro:IPR041611|interpro:IPR041641|mint:Q9P1Z2|entrezgene/locuslink:57658(identity)	refseq:NP_013793.1|sgd:S000004681|mint:Q04264|dip:DIP-6799N|ensemblfungi:YMR076C(gene)|ensemblfungi:YMR076C_mRNA(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0035808"(meiotic recombination initiation complex)|go:"GO:0042138"(meiotic DNA double-strand break formation)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0140588"(chromatin looping)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR032682|interpro:IPR039776|rcsb pdb:5FRP|rcsb pdb:5FRR|rcsb pdb:5FRS|reactome:R-SCE-2468052|reactome:R-SCE-2500257|sgd:YMR076C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:4M9Qyq+7GZ1w2UAN6k0ntGQNTvw9606	rogid:JtsuFYTdfc1TRvCvtjuJ8AAHCoU559292	intact-crc:D4CB9DC8A985D3E0|rigid:xsK8GEqbD9RUATwoolwsYbSf/uw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O95198	uniprotkb:Q04264	intact:EBI-746999|uniprotkb:B2RD18|uniprotkb:Q8N484|uniprotkb:Q8TBH5|uniprotkb:A6NCM7|uniprotkb:B4DFH7|uniprotkb:F5H6M3|ensembl:ENSP00000226725	intact:EBI-13077|uniprotkb:Q04780|uniprotkb:D6VZQ0|ensemblfungi:YMR076C	psi-mi:klhl2_human(display_long)|uniprotkb:Actin-binding protein Mayven(gene name synonym)|uniprotkb:KLHL2(gene name)|psi-mi:KLHL2(display_short)	psi-mi:pds5_yeast(display_long)|uniprotkb:PDS5(gene name)|psi-mi:PDS5(display_short)|uniprotkb:YMR076C(locus name)|uniprotkb:YM9916.15C(orf name)|uniprotkb:YM9582.01C(orf name)|uniprotkb:Precocious dissociation of sisters protein 5(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11545566|imex:IM-24995-2451	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001154993.1|refseq:NP_001154994.1|refseq:NP_009177.3|refseq:NP_001317952.1|refseq:NP_001317953.1|refseq:XP_016863165.1|ensembl:ENSG00000109466(gene)|ensembl:ENST00000226725(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030027"(lamellipodium)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR017096(Kelch-like protein, gigaxonin)|interpro:IPR044072|mint:O95198|rcsb pdb:2XN4|rcsb pdb:4CHB|reactome:R-HSA-8951664|reactome:R-HSA-983168|go:"GO:0042802"(identical protein binding)|entrezgene/locuslink:11275(identity)	refseq:NP_013793.1|sgd:S000004681|mint:Q04264|dip:DIP-6799N|ensemblfungi:YMR076C(gene)|ensemblfungi:YMR076C_mRNA(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0035808"(meiotic recombination initiation complex)|go:"GO:0042138"(meiotic DNA double-strand break formation)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0140588"(chromatin looping)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR032682|interpro:IPR039776|rcsb pdb:5FRP|rcsb pdb:5FRR|rcsb pdb:5FRS|reactome:R-SCE-2468052|reactome:R-SCE-2500257|sgd:YMR076C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:tFegR2lJZccRqs4qUjdT3PNjNnk9606	rogid:JtsuFYTdfc1TRvCvtjuJ8AAHCoU559292	intact-crc:11E697D20111A9D5|rigid:eApCGZd/gWtKLU55u76zojhWfPI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q04201	uniprotkb:Q9UMX0	intact:EBI-27928|uniprotkb:D6W0I3|ensemblfungi:YML101C	intact:EBI-741480|uniprotkb:Q8IXS9|uniprotkb:Q8N2Q3|uniprotkb:Q9H0T8|uniprotkb:Q9H3R4|uniprotkb:Q9HAZ5|intact:EBI-28967608|ensembl:ENSP00000365576|uniprotkb:Q5T6J5|uniprotkb:Q5T6J9|uniprotkb:A0A024R284	psi-mi:cue4_yeast(display_long)|uniprotkb:YML101C(locus name)|uniprotkb:Coupling of ubiquitin conjugation to ER degradation protein 4(gene name synonym)|uniprotkb:CUE4(gene name)|psi-mi:CUE4(display_short)	psi-mi:ubql1_human(display_long)|uniprotkb:Protein linking IAP with cytoskeleton 1(gene name synonym)|uniprotkb:UBQLN1(gene name)|psi-mi:UBQLN1(display_short)|uniprotkb:DA41(gene name synonym)|uniprotkb:PLIC1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11545557|imex:IM-24995-2450	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013607.1|sgd:S000004568|dip:DIP-4525N|mint:Q04201|ensemblfungi:YML101C(gene)|ensemblfungi:YML101C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR003892(Ubiquitin system component Cue)|sgd:YML101C(identity)	ensembl:ENST00000257468|ensembl:ENSP00000257468|ensembl:ENSP00000365576|ensembl:ENSG00000135018(gene)|ensembl:ENST00000376395(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000502"(proteasome complex)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016235"(aggresome)|go:"GO:0016236"(macroautophagy)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0019900"(kinase binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035973"(aggrephagy)|go:"GO:0042802"(identical protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0097352"(autophagosome maturation)|go:"GO:1901340"(negative regulation of store-operated calcium channel activity)|go:"GO:1902175"(regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)|interpro:IPR000626(Ubiquitin)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR028430|interpro:IPR029071|mint:Q9UMX0|rcsb pdb:2JY5|rcsb pdb:2JY6|rcsb pdb:2KLC|reactome:R-HSA-8856825|refseq:NP_038466.2|refseq:NP_444295.1|dip:DIP-41629N|entrezgene/locuslink:29979(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:NMBJHZbX4/gU01fk4evPDXm/M6w559292	rogid:nCFfZbGCTvRYaXhQ4R99XblslvM9606	intact-crc:E3E63962F39FAE83|rigid:ZKinB3+wtv/LmQxyK10PpKsDcag	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q13422-7	uniprotkb:Q04307	intact:EBI-11522367|ensembl:ENSP00000352123|ensembl:ENSP00000413025	intact:EBI-15858|uniprotkb:Q2VQW5|ensemblfungi:YDR045C|uniprotkb:D6VS33	psi-mi:q13422-7(display_long)|uniprotkb:IKZF1(gene name)|psi-mi:IKZF1(display_short)|uniprotkb:IK1(gene name synonym)|uniprotkb:IKAROS(gene name synonym)|uniprotkb:Ikaros family zinc finger protein 1(gene name synonym)|uniprotkb:LYF1(gene name synonym)|uniprotkb:Lymphoid transcription factor LyF-1(gene name synonym)|uniprotkb:ZNFN1A1(gene name synonym)	psi-mi:rpc10_yeast(display_long)|uniprotkb:RPC11(gene name)|psi-mi:RPC11(display_short)|uniprotkb:YDR045C(locus name)|uniprotkb:YD9609.01C(orf name)|uniprotkb:RNA polymerase III subunit C11(gene name synonym)|uniprotkb:DNA-directed RNA polymerases III 12.5 kDa polypeptide(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11545622|imex:IM-24995-2457	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-745305(isoform-parent)|ensembl:ENSG00000185811(gene)|ensembl:ENST00000359197(transcript)|ensembl:ENST00000439701(transcript)|uniprotkb:Q13422-7(isoform-parent)|entrezgene/locuslink:10320(identity)	ensemblfungi:YDR045C(gene)|refseq:NP_010330.1|sgd:S000002452|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006386"(termination of RNA polymerase III transcription)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042779"(tRNA 3'-trailer cleavage)|go:"GO:0042797"(tRNA transcription by RNA polymerase III)|interpro:IPR001222(Zinc finger, TFIIS-type)|interpro:IPR001529(DNA-directed RNA polymerase, M/15 kDa subunit)|interpro:IPR012164(DNA-directed RNA polymerase, subunit C11/M/9)|interpro:IPR019761|interpro:IPR034014|rcsb pdb:3QT1|ensemblfungi:YDR045C_mRNA(transcript)|rcsb pdb:5FJ8|rcsb pdb:5FJ9|rcsb pdb:5FJA|rcsb pdb:6CNB|rcsb pdb:6CNC|rcsb pdb:6CND|rcsb pdb:6CNF|rcsb pdb:6EU0|rcsb pdb:6EU2|rcsb pdb:6EU3|rcsb pdb:6F40|rcsb pdb:6F41|rcsb pdb:6F42|rcsb pdb:6F44|rcsb pdb:6TUT|reactome:R-SCE-76061|reactome:R-SCE-76066|rcsb pdb:6EU1|dip:DIP-887N|mint:Q04307|sgd:YDR045C(identity)	-	-	crc64:E4AA802EC9F92230	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:ou/ovXYoMneBNVp4pj38VxenfyY9606	rogid:G2fIQbptabHIUI224iPtTJF+dIs559292	intact-crc:CA40B428BDBD3B0B|rigid:AguOrpXzwc0g3NAN036O7vb92XI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32321	uniprotkb:Q04307	intact:EBI-739870|uniprotkb:Q9BVD8|uniprotkb:B2R836|uniprotkb:Q5M7Z8|uniprotkb:D3DP49|uniprotkb:D3DP50|ensembl:ENSP00000398194|ensembl:ENSP00000424017	intact:EBI-15858|uniprotkb:Q2VQW5|ensemblfungi:YDR045C|uniprotkb:D6VS33	psi-mi:dctd_human(display_long)|uniprotkb:DCTD(gene name)|psi-mi:DCTD(display_short)|uniprotkb:dCMP deaminase(gene name synonym)	psi-mi:rpc10_yeast(display_long)|uniprotkb:RPC11(gene name)|psi-mi:RPC11(display_short)|uniprotkb:YDR045C(locus name)|uniprotkb:YD9609.01C(orf name)|uniprotkb:RNA polymerase III subunit C11(gene name synonym)|uniprotkb:DNA-directed RNA polymerases III 12.5 kDa polypeptide(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11545613|imex:IM-24995-2456	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001012750.1|refseq:NP_001912.2|ensembl:ENSG00000129187(gene)|ensembl:ENST00000438320(transcript)|ensembl:ENST00000510370(transcript)|go:"GO:0004132"(dCMP deaminase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006220"(pyrimidine nucleotide metabolic process)|go:"GO:0006226"(dUMP biosynthetic process)|go:"GO:0006231"(dTMP biosynthetic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR002125(CMP/dCMP deaminase, zinc-binding)|interpro:IPR015517(Cytidine deaminase)|interpro:IPR016192(APOBEC/CMP deaminase, zinc-binding)|interpro:IPR016193(Cytidine deaminase-like)|interpro:IPR016473(dCMP deaminase)|interpro:IPR035105|mint:P32321|rcsb pdb:2W4L|reactome:R-HSA-499943|refseq:XP_005262836.1|refseq:XP_005262837.1|refseq:XP_011529976.1|refseq:XP_016863305.1|refseq:XP_016863306.1|refseq:XP_016863307.1|refseq:XP_016863308.1|refseq:XP_016863309.1|refseq:XP_016863310.1|refseq:XP_016863311.1|entrezgene/locuslink:1635(identity)	ensemblfungi:YDR045C(gene)|refseq:NP_010330.1|sgd:S000002452|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006386"(termination of RNA polymerase III transcription)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042779"(tRNA 3'-trailer cleavage)|go:"GO:0042797"(tRNA transcription by RNA polymerase III)|interpro:IPR001222(Zinc finger, TFIIS-type)|interpro:IPR001529(DNA-directed RNA polymerase, M/15 kDa subunit)|interpro:IPR012164(DNA-directed RNA polymerase, subunit C11/M/9)|interpro:IPR019761|interpro:IPR034014|rcsb pdb:3QT1|ensemblfungi:YDR045C_mRNA(transcript)|rcsb pdb:5FJ8|rcsb pdb:5FJ9|rcsb pdb:5FJA|rcsb pdb:6CNB|rcsb pdb:6CNC|rcsb pdb:6CND|rcsb pdb:6CNF|rcsb pdb:6EU0|rcsb pdb:6EU2|rcsb pdb:6EU3|rcsb pdb:6F40|rcsb pdb:6F41|rcsb pdb:6F42|rcsb pdb:6F44|rcsb pdb:6TUT|reactome:R-SCE-76061|reactome:R-SCE-76066|rcsb pdb:6EU1|dip:DIP-887N|mint:Q04307|sgd:YDR045C(identity)	-	-	crc64:E4AA802EC9F92230	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:lU3gEi7XdIJbuPlMkForbVKEOyY9606	rogid:G2fIQbptabHIUI224iPtTJF+dIs559292	intact-crc:0B9C3484D9F53626|rigid:C+v6NwAw2T/AZMrpbmOP+ZTq6cI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q04307	uniprotkb:O94993	intact:EBI-15858|uniprotkb:Q2VQW5|ensemblfungi:YDR045C|uniprotkb:D6VS33	intact:EBI-742973|ensembl:ENSP00000265007|uniprotkb:O94995|uniprotkb:Q8IYX6	psi-mi:rpc10_yeast(display_long)|uniprotkb:RPC11(gene name)|psi-mi:RPC11(display_short)|uniprotkb:YDR045C(locus name)|uniprotkb:YD9609.01C(orf name)|uniprotkb:RNA polymerase III subunit C11(gene name synonym)|uniprotkb:DNA-directed RNA polymerases III 12.5 kDa polypeptide(gene name synonym)	psi-mi:sox30_human(display_long)|uniprotkb:SOX30(gene name)|psi-mi:SOX30(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11545604|imex:IM-24995-2455	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YDR045C(gene)|refseq:NP_010330.1|sgd:S000002452|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006386"(termination of RNA polymerase III transcription)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042779"(tRNA 3'-trailer cleavage)|go:"GO:0042797"(tRNA transcription by RNA polymerase III)|interpro:IPR001222(Zinc finger, TFIIS-type)|interpro:IPR001529(DNA-directed RNA polymerase, M/15 kDa subunit)|interpro:IPR012164(DNA-directed RNA polymerase, subunit C11/M/9)|interpro:IPR019761|interpro:IPR034014|rcsb pdb:3QT1|ensemblfungi:YDR045C_mRNA(transcript)|rcsb pdb:5FJ8|rcsb pdb:5FJ9|rcsb pdb:5FJA|rcsb pdb:6CNB|rcsb pdb:6CNC|rcsb pdb:6CND|rcsb pdb:6CNF|rcsb pdb:6EU0|rcsb pdb:6EU2|rcsb pdb:6EU3|rcsb pdb:6F40|rcsb pdb:6F41|rcsb pdb:6F42|rcsb pdb:6F44|rcsb pdb:6TUT|reactome:R-SCE-76061|reactome:R-SCE-76066|rcsb pdb:6EU1|dip:DIP-887N|mint:Q04307|sgd:YDR045C(identity)	rcsb pdb:7JJK|refseq:NP_008948.1|refseq:NP_848511.1|ensembl:ENSG00000039600(gene)|ensembl:ENST00000265007(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007286"(spermatid development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0010369"(chromocenter)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0031960"(response to corticosteroid)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0120211"(proacrosomal vesicle fusion)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR036910|refseq:NP_001295094.1|entrezgene/locuslink:11063(identity)	-	crc64:E4AA802EC9F92230	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:G2fIQbptabHIUI224iPtTJF+dIs559292	rogid:AriyqffK8zuvudW4qjQ9SvnA0Vg9606	intact-crc:B0292BB0277B5743|rigid:xzx0s+fgkwgoNfQYRTGCdsfHnvo	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q04307	uniprotkb:Q7Z6G3-2	intact:EBI-15858|uniprotkb:Q2VQW5|ensemblfungi:YDR045C|uniprotkb:D6VS33	intact:EBI-10172876|ensembl:ENSP00000457354|intact:EBI-14062040	psi-mi:rpc10_yeast(display_long)|uniprotkb:RPC11(gene name)|psi-mi:RPC11(display_short)|uniprotkb:YDR045C(locus name)|uniprotkb:YD9609.01C(orf name)|uniprotkb:RNA polymerase III subunit C11(gene name synonym)|uniprotkb:DNA-directed RNA polymerases III 12.5 kDa polypeptide(gene name synonym)	psi-mi:q7z6g3-2(display_long)|uniprotkb:EFCBP2(gene name synonym)|uniprotkb:Neuronal calcium-binding protein 2(gene name synonym)|uniprotkb:Synaptotagmin-interacting protein 2(gene name synonym)|uniprotkb:NECAB2(gene name)|psi-mi:NECAB2(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11545593|imex:IM-24995-2454	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YDR045C(gene)|refseq:NP_010330.1|sgd:S000002452|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006386"(termination of RNA polymerase III transcription)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042779"(tRNA 3'-trailer cleavage)|go:"GO:0042797"(tRNA transcription by RNA polymerase III)|interpro:IPR001222(Zinc finger, TFIIS-type)|interpro:IPR001529(DNA-directed RNA polymerase, M/15 kDa subunit)|interpro:IPR012164(DNA-directed RNA polymerase, subunit C11/M/9)|interpro:IPR019761|interpro:IPR034014|rcsb pdb:3QT1|ensemblfungi:YDR045C_mRNA(transcript)|rcsb pdb:5FJ8|rcsb pdb:5FJ9|rcsb pdb:5FJA|rcsb pdb:6CNB|rcsb pdb:6CNC|rcsb pdb:6CND|rcsb pdb:6CNF|rcsb pdb:6EU0|rcsb pdb:6EU2|rcsb pdb:6EU3|rcsb pdb:6F40|rcsb pdb:6F41|rcsb pdb:6F42|rcsb pdb:6F44|rcsb pdb:6TUT|reactome:R-SCE-76061|reactome:R-SCE-76066|rcsb pdb:6EU1|dip:DIP-887N|mint:Q04307|sgd:YDR045C(identity)	ensembl:ENSG00000103154(gene)|ensembl:ENST00000565691(transcript)|uniprotkb:Q7Z6G3-2(isoform-parent)|intact:EBI-950070(isoform-parent)|entrezgene/locuslink:54550(identity)	-	crc64:E4AA802EC9F92230	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:G2fIQbptabHIUI224iPtTJF+dIs559292	rogid:4S7oIx6h+mKzV3EPxqcfMNqaNko9606	intact-crc:6025E76F7BD33F75|rigid:Um+HMOYZtBTpcWmb37no39hEDIw	false	-	sufficient binding region:65-303	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8IYA8	uniprotkb:Q04307	intact:EBI-8638439|intact:EBI-28969497|ensembl:ENSP00000296449|ensembl:ENSP00000391788|ensembl:ENSP00000407837|uniprotkb:C9JJL0|uniprotkb:Q96LP7|intact:MINT-8162095|uniprotkb:Q05DG9	intact:EBI-15858|uniprotkb:Q2VQW5|ensemblfungi:YDR045C|uniprotkb:D6VS33	psi-mi:iho1_human(display_long)|uniprotkb:IHO1(gene name)|psi-mi:IHO1(display_short)|uniprotkb:CCDC36(gene name synonym)|uniprotkb:Cancer/testis antigen 74(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 36(gene name synonym)	psi-mi:rpc10_yeast(display_long)|uniprotkb:RPC11(gene name)|psi-mi:RPC11(display_short)|uniprotkb:YDR045C(locus name)|uniprotkb:YD9609.01C(orf name)|uniprotkb:RNA polymerase III subunit C11(gene name synonym)|uniprotkb:DNA-directed RNA polymerases III 12.5 kDa polypeptide(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11545651|imex:IM-24995-2460	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000296449|ensembl:ENST00000366429|ensembl:ENSP00000403700|ensembl:ENSP00000391788|ensembl:ENSP00000407837|ensembl:ENSG00000173421(gene)|ensembl:ENST00000296449(transcript)|ensembl:ENST00000438782(transcript)|ensembl:ENST00000452691(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0006310"(DNA recombination)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0042138"(meiotic DNA double-strand break formation)|go:"GO:0048477"(oogenesis)|go:"GO:0060629"(regulation of homologous chromosome segregation)|interpro:IPR031529|mint:Q8IYA8|refseq:XP_011531974.1|refseq:XP_011531975.1|refseq:NP_001128669.1|refseq:NP_835467.2|refseq:XP_006713187.1|entrezgene/locuslink:339834(identity)	ensemblfungi:YDR045C(gene)|refseq:NP_010330.1|sgd:S000002452|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006386"(termination of RNA polymerase III transcription)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042779"(tRNA 3'-trailer cleavage)|go:"GO:0042797"(tRNA transcription by RNA polymerase III)|interpro:IPR001222(Zinc finger, TFIIS-type)|interpro:IPR001529(DNA-directed RNA polymerase, M/15 kDa subunit)|interpro:IPR012164(DNA-directed RNA polymerase, subunit C11/M/9)|interpro:IPR019761|interpro:IPR034014|rcsb pdb:3QT1|ensemblfungi:YDR045C_mRNA(transcript)|rcsb pdb:5FJ8|rcsb pdb:5FJ9|rcsb pdb:5FJA|rcsb pdb:6CNB|rcsb pdb:6CNC|rcsb pdb:6CND|rcsb pdb:6CNF|rcsb pdb:6EU0|rcsb pdb:6EU2|rcsb pdb:6EU3|rcsb pdb:6F40|rcsb pdb:6F41|rcsb pdb:6F42|rcsb pdb:6F44|rcsb pdb:6TUT|reactome:R-SCE-76061|reactome:R-SCE-76066|rcsb pdb:6EU1|dip:DIP-887N|mint:Q04307|sgd:YDR045C(identity)	-	comment:mint	crc64:E4AA802EC9F92230	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:+TNQLExkhmC1NWqsE240Cx7zFVU9606	rogid:G2fIQbptabHIUI224iPtTJF+dIs559292	intact-crc:F4CB272AB8276166|rigid:LjCxaMqrV6DJwAVZcb9AK1ol74s	false	sufficient binding region:11-594	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q04307	uniprotkb:Q6P1W5	intact:EBI-15858|uniprotkb:Q2VQW5|ensemblfungi:YDR045C|uniprotkb:D6VS33	intact:EBI-946029|uniprotkb:B3KVT1|uniprotkb:Q96IC8|ensembl:ENSP00000435634|uniprotkb:D3DPR3|uniprotkb:E9PJ76	psi-mi:rpc10_yeast(display_long)|uniprotkb:RPC11(gene name)|psi-mi:RPC11(display_short)|uniprotkb:YDR045C(locus name)|uniprotkb:YD9609.01C(orf name)|uniprotkb:RNA polymerase III subunit C11(gene name synonym)|uniprotkb:DNA-directed RNA polymerases III 12.5 kDa polypeptide(gene name synonym)	psi-mi:ca094_human(display_long)|uniprotkb:C1orf94(gene name)|psi-mi:C1orf94(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11545640|imex:IM-24995-2459	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YDR045C(gene)|refseq:NP_010330.1|sgd:S000002452|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006386"(termination of RNA polymerase III transcription)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042779"(tRNA 3'-trailer cleavage)|go:"GO:0042797"(tRNA transcription by RNA polymerase III)|interpro:IPR001222(Zinc finger, TFIIS-type)|interpro:IPR001529(DNA-directed RNA polymerase, M/15 kDa subunit)|interpro:IPR012164(DNA-directed RNA polymerase, subunit C11/M/9)|interpro:IPR019761|interpro:IPR034014|rcsb pdb:3QT1|ensemblfungi:YDR045C_mRNA(transcript)|rcsb pdb:5FJ8|rcsb pdb:5FJ9|rcsb pdb:5FJA|rcsb pdb:6CNB|rcsb pdb:6CNC|rcsb pdb:6CND|rcsb pdb:6CNF|rcsb pdb:6EU0|rcsb pdb:6EU2|rcsb pdb:6EU3|rcsb pdb:6F40|rcsb pdb:6F41|rcsb pdb:6F42|rcsb pdb:6F44|rcsb pdb:6TUT|reactome:R-SCE-76061|reactome:R-SCE-76066|rcsb pdb:6EU1|dip:DIP-887N|mint:Q04307|sgd:YDR045C(identity)	refseq:NP_001128206.1|refseq:NP_116273.2|ensembl:ENSG00000142698(gene)|ensembl:ENST00000488417(transcript)|interpro:IPR031496|entrezgene/locuslink:84970(identity)	-	crc64:E4AA802EC9F92230	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:G2fIQbptabHIUI224iPtTJF+dIs559292	rogid:y1o4xWvTl2CBA1J7jsP7y8ZjLzM9606	intact-crc:32C2C260D8811050|rigid:lAblKOzNr1tiUBq1jkBoEwAh1X0	false	-	sufficient binding region:191-598	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q15645	uniprotkb:Q04307	intact:EBI-358993|uniprotkb:C9K0T3|uniprotkb:O15324|ensembl:ENSP00000166345|uniprotkb:D3DTC0	intact:EBI-15858|uniprotkb:Q2VQW5|ensemblfungi:YDR045C|uniprotkb:D6VS33	psi-mi:pch2_human(display_long)|uniprotkb:TRIP13(gene name)|psi-mi:TRIP13(display_short)|uniprotkb:Thyroid receptor-interacting protein 13(gene name synonym)|uniprotkb:PCH2(gene name synonym)|uniprotkb:Thyroid hormone receptor interactor 13(gene name synonym)|uniprotkb:Human papillomavirus type 16 E1 protein-binding protein(gene name synonym)	psi-mi:rpc10_yeast(display_long)|uniprotkb:RPC11(gene name)|psi-mi:RPC11(display_short)|uniprotkb:YDR045C(locus name)|uniprotkb:YD9609.01C(orf name)|uniprotkb:RNA polymerase III subunit C11(gene name synonym)|uniprotkb:DNA-directed RNA polymerases III 12.5 kDa polypeptide(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11545631|imex:IM-24995-2458	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004228.1|ensembl:ENSG00000071539(gene)|ensembl:ENST00000166345(transcript)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|refseq:XP_011512465.1|dip:DIP-34493N|go:"GO:0005694"(chromosome)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0007141"(male meiosis I)|go:"GO:0007144"(female meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007286"(spermatid development)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051598"(meiotic recombination checkpoint signaling)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR027417|interpro:IPR044539|mint:Q15645|rcsb pdb:5VQ9|rcsb pdb:5VQA|rcsb pdb:5WC2|rcsb pdb:6F0X|rcsb pdb:6LK0|rcsb pdb:7L9P|entrezgene/locuslink:9319(identity)	ensemblfungi:YDR045C(gene)|refseq:NP_010330.1|sgd:S000002452|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006386"(termination of RNA polymerase III transcription)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042779"(tRNA 3'-trailer cleavage)|go:"GO:0042797"(tRNA transcription by RNA polymerase III)|interpro:IPR001222(Zinc finger, TFIIS-type)|interpro:IPR001529(DNA-directed RNA polymerase, M/15 kDa subunit)|interpro:IPR012164(DNA-directed RNA polymerase, subunit C11/M/9)|interpro:IPR019761|interpro:IPR034014|rcsb pdb:3QT1|ensemblfungi:YDR045C_mRNA(transcript)|rcsb pdb:5FJ8|rcsb pdb:5FJ9|rcsb pdb:5FJA|rcsb pdb:6CNB|rcsb pdb:6CNC|rcsb pdb:6CND|rcsb pdb:6CNF|rcsb pdb:6EU0|rcsb pdb:6EU2|rcsb pdb:6EU3|rcsb pdb:6F40|rcsb pdb:6F41|rcsb pdb:6F42|rcsb pdb:6F44|rcsb pdb:6TUT|reactome:R-SCE-76061|reactome:R-SCE-76066|rcsb pdb:6EU1|dip:DIP-887N|mint:Q04307|sgd:YDR045C(identity)	-	-	crc64:E4AA802EC9F92230	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:heF2f3R2lGIpZ80mZHnhMktXTE49606	rogid:G2fIQbptabHIUI224iPtTJF+dIs559292	intact-crc:9A14E3C5F4CA40EF|rigid:xjGEbc9I5sNUM3H74oZtdRfa8/k	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8TAP6	uniprotkb:Q04307	intact:EBI-742887|ensembl:ENSP00000262127|uniprotkb:Q658N5|uniprotkb:Q9H9U7|uniprotkb:B0YJB2|uniprotkb:B4DXG5|uniprotkb:B4DZW1	intact:EBI-15858|uniprotkb:Q2VQW5|ensemblfungi:YDR045C|uniprotkb:D6VS33	psi-mi:cep76_human(display_long)|uniprotkb:CEP76(gene name)|psi-mi:CEP76(display_short)|uniprotkb:C18orf9(gene name synonym)	psi-mi:rpc10_yeast(display_long)|uniprotkb:RPC11(gene name)|psi-mi:RPC11(display_short)|uniprotkb:YDR045C(locus name)|uniprotkb:YD9609.01C(orf name)|uniprotkb:RNA polymerase III subunit C11(gene name synonym)|uniprotkb:DNA-directed RNA polymerases III 12.5 kDa polypeptide(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11545682|imex:IM-24995-2463	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_079175.2|ensembl:ENSG00000101624(gene)|ensembl:ENST00000262127(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0046599"(regulation of centriole replication)|interpro:IPR028926|interpro:IPR038765|mint:Q8TAP6|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_001258918.1|entrezgene/locuslink:79959(identity)	ensemblfungi:YDR045C(gene)|refseq:NP_010330.1|sgd:S000002452|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006386"(termination of RNA polymerase III transcription)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042779"(tRNA 3'-trailer cleavage)|go:"GO:0042797"(tRNA transcription by RNA polymerase III)|interpro:IPR001222(Zinc finger, TFIIS-type)|interpro:IPR001529(DNA-directed RNA polymerase, M/15 kDa subunit)|interpro:IPR012164(DNA-directed RNA polymerase, subunit C11/M/9)|interpro:IPR019761|interpro:IPR034014|rcsb pdb:3QT1|ensemblfungi:YDR045C_mRNA(transcript)|rcsb pdb:5FJ8|rcsb pdb:5FJ9|rcsb pdb:5FJA|rcsb pdb:6CNB|rcsb pdb:6CNC|rcsb pdb:6CND|rcsb pdb:6CNF|rcsb pdb:6EU0|rcsb pdb:6EU2|rcsb pdb:6EU3|rcsb pdb:6F40|rcsb pdb:6F41|rcsb pdb:6F42|rcsb pdb:6F44|rcsb pdb:6TUT|reactome:R-SCE-76061|reactome:R-SCE-76066|rcsb pdb:6EU1|dip:DIP-887N|mint:Q04307|sgd:YDR045C(identity)	-	-	crc64:E4AA802EC9F92230	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:fWzb8oIU35oVWomyDrf8u5sbxUk9606	rogid:G2fIQbptabHIUI224iPtTJF+dIs559292	intact-crc:ED137B93B8DE8548|rigid:weMc+1uTiK5j8BMXnQgGYI5a/DA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8ND30	uniprotkb:Q04307	intact:EBI-744056|uniprotkb:O75337|uniprotkb:Q8WW26|intact:EBI-28975311|uniprotkb:B7Z433|uniprotkb:E9PK77|ensembl:ENSP00000299492	intact:EBI-15858|uniprotkb:Q2VQW5|ensemblfungi:YDR045C|uniprotkb:D6VS33	psi-mi:lipb2_human(display_long)|uniprotkb:Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 2(gene name synonym)|uniprotkb:PPFIBP2(gene name)|psi-mi:PPFIBP2(display_short)	psi-mi:rpc10_yeast(display_long)|uniprotkb:RPC11(gene name)|psi-mi:RPC11(display_short)|uniprotkb:YDR045C(locus name)|uniprotkb:YD9609.01C(orf name)|uniprotkb:RNA polymerase III subunit C11(gene name synonym)|uniprotkb:DNA-directed RNA polymerases III 12.5 kDa polypeptide(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11545673|imex:IM-24995-2462	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003612.2|ensembl:ENSP00000299492|ensembl:ENST00000528883|ensembl:ENSP00000435469|ensembl:ENST00000530181|ensembl:ENSP00000437321|refseq:NP_001243497.1|refseq:XP_016873932.1|dip:DIP-42373N|ensembl:ENSG00000166387(gene)|ensembl:ENST00000299492(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0042802"(identical protein binding)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0050808"(synapse organization)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR029515|interpro:IPR030435|interpro:IPR037617|interpro:IPR037618|interpro:IPR037619|mint:Q8ND30|rcsb pdb:3QH9|reactome:R-HSA-388844|entrezgene/locuslink:8495(identity)	ensemblfungi:YDR045C(gene)|refseq:NP_010330.1|sgd:S000002452|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006386"(termination of RNA polymerase III transcription)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042779"(tRNA 3'-trailer cleavage)|go:"GO:0042797"(tRNA transcription by RNA polymerase III)|interpro:IPR001222(Zinc finger, TFIIS-type)|interpro:IPR001529(DNA-directed RNA polymerase, M/15 kDa subunit)|interpro:IPR012164(DNA-directed RNA polymerase, subunit C11/M/9)|interpro:IPR019761|interpro:IPR034014|rcsb pdb:3QT1|ensemblfungi:YDR045C_mRNA(transcript)|rcsb pdb:5FJ8|rcsb pdb:5FJ9|rcsb pdb:5FJA|rcsb pdb:6CNB|rcsb pdb:6CNC|rcsb pdb:6CND|rcsb pdb:6CNF|rcsb pdb:6EU0|rcsb pdb:6EU2|rcsb pdb:6EU3|rcsb pdb:6F40|rcsb pdb:6F41|rcsb pdb:6F42|rcsb pdb:6F44|rcsb pdb:6TUT|reactome:R-SCE-76061|reactome:R-SCE-76066|rcsb pdb:6EU1|dip:DIP-887N|mint:Q04307|sgd:YDR045C(identity)	-	-	crc64:E4AA802EC9F92230	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:36bMLWHJuGN5eItyc1HvhoLonZA9606	rogid:G2fIQbptabHIUI224iPtTJF+dIs559292	intact-crc:F7F2C20B13A3CFB4|rigid:Q9dj5jef7/lx/22Iu6UUYIJH55M	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q04307	uniprotkb:Q8N7W2-2	intact:EBI-15858|uniprotkb:Q2VQW5|ensemblfungi:YDR045C|uniprotkb:D6VS33	intact:EBI-10181188|ensembl:ENSP00000367868	psi-mi:rpc10_yeast(display_long)|uniprotkb:RPC11(gene name)|psi-mi:RPC11(display_short)|uniprotkb:YDR045C(locus name)|uniprotkb:YD9609.01C(orf name)|uniprotkb:RNA polymerase III subunit C11(gene name synonym)|uniprotkb:DNA-directed RNA polymerases III 12.5 kDa polypeptide(gene name synonym)	psi-mi:q8n7w2-2(display_long)|uniprotkb:C10orf30(gene name synonym)|uniprotkb:BEND7(gene name)|psi-mi:BEND7(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11545662|imex:IM-24995-2461	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YDR045C(gene)|refseq:NP_010330.1|sgd:S000002452|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006386"(termination of RNA polymerase III transcription)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042779"(tRNA 3'-trailer cleavage)|go:"GO:0042797"(tRNA transcription by RNA polymerase III)|interpro:IPR001222(Zinc finger, TFIIS-type)|interpro:IPR001529(DNA-directed RNA polymerase, M/15 kDa subunit)|interpro:IPR012164(DNA-directed RNA polymerase, subunit C11/M/9)|interpro:IPR019761|interpro:IPR034014|rcsb pdb:3QT1|ensemblfungi:YDR045C_mRNA(transcript)|rcsb pdb:5FJ8|rcsb pdb:5FJ9|rcsb pdb:5FJA|rcsb pdb:6CNB|rcsb pdb:6CNC|rcsb pdb:6CND|rcsb pdb:6CNF|rcsb pdb:6EU0|rcsb pdb:6EU2|rcsb pdb:6EU3|rcsb pdb:6F40|rcsb pdb:6F41|rcsb pdb:6F42|rcsb pdb:6F44|rcsb pdb:6TUT|reactome:R-SCE-76061|reactome:R-SCE-76066|rcsb pdb:6EU1|dip:DIP-887N|mint:Q04307|sgd:YDR045C(identity)	ensembl:ENSG00000165626(gene)|ensembl:ENST00000378605(transcript)|intact:EBI-743382(isoform-parent)|uniprotkb:Q8N7W2-2(isoform-parent)|entrezgene/locuslink:222389(identity)	-	crc64:E4AA802EC9F92230	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:G2fIQbptabHIUI224iPtTJF+dIs559292	rogid:p6qrTn80hLyVU0W2Tvwn50Q4m5I9606	intact-crc:48CF3A7545B733CF|rigid:9adlJDrnegjPAP7J4eGktnx2ZJI	false	-	sufficient binding region:10-374	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q04307	uniprotkb:Q9UJW9	intact:EBI-15858|uniprotkb:Q2VQW5|ensemblfungi:YDR045C|uniprotkb:D6VS33	intact:EBI-748621|uniprotkb:Q96CQ2|uniprotkb:B3KQB3|ensembl:ENSP00000325414|ensembl:ENSP00000375882	psi-mi:rpc10_yeast(display_long)|uniprotkb:RPC11(gene name)|psi-mi:RPC11(display_short)|uniprotkb:YDR045C(locus name)|uniprotkb:YD9609.01C(orf name)|uniprotkb:RNA polymerase III subunit C11(gene name synonym)|uniprotkb:DNA-directed RNA polymerases III 12.5 kDa polypeptide(gene name synonym)	psi-mi:srtd3_human(display_long)|uniprotkb:Replication protein-binding trans-activator(gene name synonym)|uniprotkb:SERTAD3(gene name)|psi-mi:SERTAD3(display_short)|uniprotkb:RBT1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11545709|imex:IM-24995-2466	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YDR045C(gene)|refseq:NP_010330.1|sgd:S000002452|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006386"(termination of RNA polymerase III transcription)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042779"(tRNA 3'-trailer cleavage)|go:"GO:0042797"(tRNA transcription by RNA polymerase III)|interpro:IPR001222(Zinc finger, TFIIS-type)|interpro:IPR001529(DNA-directed RNA polymerase, M/15 kDa subunit)|interpro:IPR012164(DNA-directed RNA polymerase, subunit C11/M/9)|interpro:IPR019761|interpro:IPR034014|rcsb pdb:3QT1|ensemblfungi:YDR045C_mRNA(transcript)|rcsb pdb:5FJ8|rcsb pdb:5FJ9|rcsb pdb:5FJA|rcsb pdb:6CNB|rcsb pdb:6CNC|rcsb pdb:6CND|rcsb pdb:6CNF|rcsb pdb:6EU0|rcsb pdb:6EU2|rcsb pdb:6EU3|rcsb pdb:6F40|rcsb pdb:6F41|rcsb pdb:6F42|rcsb pdb:6F44|rcsb pdb:6TUT|reactome:R-SCE-76061|reactome:R-SCE-76066|rcsb pdb:6EU1|dip:DIP-887N|mint:Q04307|sgd:YDR045C(identity)	refseq:XP_006723242.1|refseq:NP_037500.2|refseq:NP_976219.1|refseq:XP_005258889.1|ensembl:ENSG00000167565(gene)|ensembl:ENST00000322354(transcript)|ensembl:ENST00000392028(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR009263(SERTA)|interpro:IPR039585|entrezgene/locuslink:29946(identity)	-	crc64:E4AA802EC9F92230	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:G2fIQbptabHIUI224iPtTJF+dIs559292	rogid:zraVKcqHA7SNRrMV50iyPK6O7ok9606	intact-crc:86360EE67658AF92|rigid:MzT3LybxicBeAZjMmgwBKUpdDGo	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q04307	uniprotkb:Q9NNX1-2	intact:EBI-15858|uniprotkb:Q2VQW5|ensemblfungi:YDR045C|uniprotkb:D6VS33	intact:EBI-11535232|ensembl:ENSP00000357841	psi-mi:rpc10_yeast(display_long)|uniprotkb:RPC11(gene name)|psi-mi:RPC11(display_short)|uniprotkb:YDR045C(locus name)|uniprotkb:YD9609.01C(orf name)|uniprotkb:RNA polymerase III subunit C11(gene name synonym)|uniprotkb:DNA-directed RNA polymerases III 12.5 kDa polypeptide(gene name synonym)	psi-mi:q9nnx1-2(display_long)|uniprotkb:TUFT1(gene name)|psi-mi:TUFT1(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11545700|imex:IM-24995-2465	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YDR045C(gene)|refseq:NP_010330.1|sgd:S000002452|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006386"(termination of RNA polymerase III transcription)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042779"(tRNA 3'-trailer cleavage)|go:"GO:0042797"(tRNA transcription by RNA polymerase III)|interpro:IPR001222(Zinc finger, TFIIS-type)|interpro:IPR001529(DNA-directed RNA polymerase, M/15 kDa subunit)|interpro:IPR012164(DNA-directed RNA polymerase, subunit C11/M/9)|interpro:IPR019761|interpro:IPR034014|rcsb pdb:3QT1|ensemblfungi:YDR045C_mRNA(transcript)|rcsb pdb:5FJ8|rcsb pdb:5FJ9|rcsb pdb:5FJA|rcsb pdb:6CNB|rcsb pdb:6CNC|rcsb pdb:6CND|rcsb pdb:6CNF|rcsb pdb:6EU0|rcsb pdb:6EU2|rcsb pdb:6EU3|rcsb pdb:6F40|rcsb pdb:6F41|rcsb pdb:6F42|rcsb pdb:6F44|rcsb pdb:6TUT|reactome:R-SCE-76061|reactome:R-SCE-76066|rcsb pdb:6EU1|dip:DIP-887N|mint:Q04307|sgd:YDR045C(identity)	intact:EBI-2557363(isoform-parent)|ensembl:ENSG00000143367(gene)|ensembl:ENST00000368848(transcript)|uniprotkb:Q9NNX1-2(isoform-parent)|entrezgene/locuslink:7286(identity)	-	crc64:E4AA802EC9F92230	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:G2fIQbptabHIUI224iPtTJF+dIs559292	rogid:Xt8rl/ePRyc25U9+KY9b8o1IcNs9606	intact-crc:5EFC47E633F04A58|rigid:LHE5xu/Xg2ztWFBt6i7YHI5S7XU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q93062-3	uniprotkb:Q04307	intact:EBI-740343|ensembl:ENSP00000340176	intact:EBI-15858|uniprotkb:Q2VQW5|ensemblfungi:YDR045C|uniprotkb:D6VS33	psi-mi:q93062-3(display_long)|uniprotkb:RBPMS(gene name)|psi-mi:RBPMS(display_short)|uniprotkb:HERMES(gene name synonym)|uniprotkb:Heart and RRM expressed sequence(gene name synonym)	psi-mi:rpc10_yeast(display_long)|uniprotkb:RPC11(gene name)|psi-mi:RPC11(display_short)|uniprotkb:YDR045C(locus name)|uniprotkb:YD9609.01C(orf name)|uniprotkb:RNA polymerase III subunit C11(gene name synonym)|uniprotkb:DNA-directed RNA polymerases III 12.5 kDa polypeptide(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11545691|imex:IM-24995-2464	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-740322(rbpms_human)|uniprotkb:Q93062-3(isoform-parent)|ensembl:ENSG00000157110(gene)|ensembl:ENST00000339877(transcript)|entrezgene/locuslink:11030(identity)	ensemblfungi:YDR045C(gene)|refseq:NP_010330.1|sgd:S000002452|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006386"(termination of RNA polymerase III transcription)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042779"(tRNA 3'-trailer cleavage)|go:"GO:0042797"(tRNA transcription by RNA polymerase III)|interpro:IPR001222(Zinc finger, TFIIS-type)|interpro:IPR001529(DNA-directed RNA polymerase, M/15 kDa subunit)|interpro:IPR012164(DNA-directed RNA polymerase, subunit C11/M/9)|interpro:IPR019761|interpro:IPR034014|rcsb pdb:3QT1|ensemblfungi:YDR045C_mRNA(transcript)|rcsb pdb:5FJ8|rcsb pdb:5FJ9|rcsb pdb:5FJA|rcsb pdb:6CNB|rcsb pdb:6CNC|rcsb pdb:6CND|rcsb pdb:6CNF|rcsb pdb:6EU0|rcsb pdb:6EU2|rcsb pdb:6EU3|rcsb pdb:6F40|rcsb pdb:6F41|rcsb pdb:6F42|rcsb pdb:6F44|rcsb pdb:6TUT|reactome:R-SCE-76061|reactome:R-SCE-76066|rcsb pdb:6EU1|dip:DIP-887N|mint:Q04307|sgd:YDR045C(identity)	-	-	crc64:E4AA802EC9F92230	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:nlPMQAJoKEbPYBwsL3xodmCKd7c9606	rogid:G2fIQbptabHIUI224iPtTJF+dIs559292	intact-crc:8232C5DAAE723FB9|rigid:ivhDb+JqObLZCtlrAtGVpM86ook	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8N5R6	uniprotkb:Q04638	intact:EBI-740841|intact:EBI-953781|uniprotkb:B3KQ49|uniprotkb:A8K3U4|uniprotkb:A8MPQ6|uniprotkb:A8MV61|uniprotkb:A8MVU9|uniprotkb:Q9H5Q6|uniprotkb:Q8TAX6|intact:EBI-2320546|intact:EBI-11522976	intact:EBI-27858|uniprotkb:D6VZA5|ensemblfungi:YML068W	psi-mi:ccd33_human(display_long)|uniprotkb:CCDC33(gene name)|psi-mi:CCDC33(display_short)|uniprotkb:Cancer/testis antigen 61(gene name synonym)	psi-mi:itt1_yeast(display_long)|uniprotkb:ITT1(gene name)|psi-mi:ITT1(display_short)|uniprotkb:YML068W(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11545747|imex:IM-24995-2470	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_079331.3|interpro:IPR000008(C2 calcium-dependent membrane targeting)|go:"GO:0005777"(peroxisome)|refseq:NP_001274110.1|refseq:NP_877592.2|mint:Q8N5R6|interpro:IPR035892|interpro:IPR039889|entrezgene/locuslink:80125(identity)	refseq:NP_013643.1|sgd:S000004533|dip:DIP-1952N|mint:Q04638|ensemblfungi:YML068W(gene)|ensemblfungi:YML068W_mRNA(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005737"(cytoplasm)|go:"GO:0006449"(regulation of translational termination)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002867(Zinc finger, C6HC-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR031127|interpro:IPR044066|sgd:YML068W(identity)	-	-	crc64:F481372B742AF63D	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2021/11/30	rogid:eEIn7pQyfdHWx8TeLJpYy0i/gww9606	rogid:gPNBZ7jeo4QD4M26MqrTGBZqVZY559292	intact-crc:FADC82D8CB2BBCC8|rigid:Rv1qP9yRgGM74WMA2bnWZQ0Rev4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q01658	uniprotkb:Q04603	intact:EBI-750300|ensembl:ENSP00000359290|ensembl:ENSP00000359295	intact:EBI-29938|uniprotkb:D6VSA7|ensemblfungi:YDR121W	psi-mi:nc2b_human(display_long)|uniprotkb:Down-regulator of transcription 1(gene name synonym)|uniprotkb:TATA-binding protein-associated phosphoprotein(gene name synonym)|uniprotkb:Negative cofactor 2-beta(gene name synonym)|uniprotkb:DR1(gene name)|psi-mi:DR1(display_short)	psi-mi:dpb4_yeast(display_long)|uniprotkb:DPB4(gene name)|psi-mi:DPB4(display_short)|uniprotkb:DNA polymerase II subunit D(gene name synonym)|uniprotkb:YDR121W(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11545738|imex:IM-24995-2469	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001929.1|ensembl:ENSG00000117505(gene)|ensembl:ENST00000370267(transcript)|ensembl:ENST00000370272(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0017054"(negative cofactor 2 complex)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR003958(Transcription factor CBF/NF-Y/archaeal histone)|interpro:IPR009072(Histone-fold)|interpro:IPR042225|mint:Q01658|rcsb pdb:1JFI|reactome:R-HSA-3214847|entrezgene/locuslink:1810(identity)	sgd:S000002528|refseq:NP_010406.3|dip:DIP-4621N|mint:Q04603|ensemblfungi:YDR121W(gene)|ensemblfungi:YDR121W_mRNA(transcript)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006272"(leading strand elongation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008622"(epsilon DNA polymerase complex)|go:"GO:0008623"(CHRAC)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0042276"(error-prone translesion synthesis)|go:"GO:0042766"(nucleosome mobilization)|go:"GO:0043044"|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0070868"(obsolete heterochromatin organization involved in chromatin silencing)|go:"GO:0090305"(nucleic acid phosphodiester bond hydrolysis)|interpro:IPR009072(Histone-fold)|rcsb pdb:6WJV|reactome:R-SCE-5656169|reactome:R-SCE-6782135|reactome:R-SCE-68952|reactome:R-SCE-68962|sgd:YDR121W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:lrcYCVWbIkFU01ETSmd3cX++jLw9606	rogid:vEA21+6hLP2O4eSSuKA49lbi0E0559292	intact-crc:AABB312B95DFAF7E|rigid:0oW2EWGQH4fLj7PWG+Nqd7E+B4U	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8N9N5-2	uniprotkb:Q04599	intact:EBI-11524452|ensembl:ENSP00000347125	intact:EBI-38719|uniprotkb:D6VSA1|ensemblfungi:YDR116C	psi-mi:q8n9n5-2(display_long)|uniprotkb:BANP(gene name)|psi-mi:BANP(display_short)|uniprotkb:BEN domain-containing protein 1(gene name synonym)|uniprotkb:BEND1(gene name synonym)|uniprotkb:Btg3-associated nuclear protein(gene name synonym)|uniprotkb:SMAR1(gene name synonym)|uniprotkb:Scaffold/matrix-associated region-1-binding protein(gene name synonym)	psi-mi:rm01_yeast(display_long)|uniprotkb:MRPL1(gene name)|psi-mi:MRPL1(display_short)|uniprotkb:Mitochondrial large ribosomal subunit protein uL1m(gene name synonym)|uniprotkb:YD9727.11C(orf name)|uniprotkb:YDR116C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11545729|imex:IM-24995-2468	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000172530(gene)|ensembl:ENST00000355022(transcript)|intact:EBI-744695(isoform-parent)|uniprotkb:Q8N9N5-2(isoform-parent)|entrezgene/locuslink:54971(identity)	refseq:NP_010401.1|sgd:S000002523|mint:Q04599|dip:DIP-5223N|ensemblfungi:YDR116C(gene)|ensemblfungi:YDR116C_mRNA(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR002143(Ribosomal protein L1)|interpro:IPR005879(Ribosomal protein L1, mitochondrial)|interpro:IPR016095(Ribosomal protein L1, 3-layer alpha/beta-sandwich)|interpro:IPR023673|interpro:IPR023674|interpro:IPR028364|sgd:YDR116C(identity)	-	-	crc64:59DB6C5D10421A77	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:ESe6iCAhvq+i57fQHz3rGyg6UOo9606	rogid:Vco7wlmhTOETdBwIRgrjIdRR92w559292	intact-crc:8F8EA5B79F7A5940|rigid:p1xQkU70QRwfT53XY1ZT+tRdRTc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:A2A369	uniprotkb:Q04461	intact:EBI-11530808|ensembl:ENSP00000371766	intact:EBI-27209|uniprotkb:D6VZT4|ensemblfungi:YMR111C	psi-mi:a2a369_human(display_long)|uniprotkb:DOCK8(gene name)|psi-mi:DOCK8(display_short)	psi-mi:euc1_yeast(display_long)|uniprotkb:EUC1(gene name)|psi-mi:EUC1(display_short)|uniprotkb:Enriches ubiquitin on chromatin protein 1(gene name synonym)|uniprotkb:YM9718.10C(orf name)|uniprotkb:YMR111C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11545718|imex:IM-24995-2467	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000107099(gene)|ensembl:ENST00000382329(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0007264"(small GTPase mediated signal transduction)|interpro:IPR010703(Dedicator of cytokinesis)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026791|interpro:IPR027007|interpro:IPR027357|interpro:IPR035892|interpro:IPR043161|interpro:IPR043162|entrezgene/locuslink:81704(identity)	refseq:NP_013829.1|sgd:S000004717|dip:DIP-2716N|ensemblfungi:YMR111C(gene)|ensemblfungi:YMR111C_mRNA(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0034629"|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0060963"(positive regulation of ribosomal protein gene transcription by RNA polymerase II)|interpro:IPR022210|sgd:YMR111C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Sa5ulmmVxrpxZ+GAhN64RAHXYdk9606	rogid:Wpg0ztvlnbV6BXPwJKqWehavPGA559292	intact-crc:7F23FBAAF89FD891|rigid:BpcaaJVBWTylkwcmkR9N9YwL7EQ	false	sufficient binding region:1054-1566	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9Y2D8	uniprotkb:Q04712	intact:EBI-2212028|uniprotkb:B4DFE3|uniprotkb:J3KR02|uniprotkb:A8K8W0|uniprotkb:D3DT13|uniprotkb:Q6P2P8|uniprotkb:Q6ULS1|uniprotkb:Q7L168|uniprotkb:Q9UIX0|intact:EBI-10964529|ensembl:ENSP00000340279	intact:EBI-27790|uniprotkb:D6VZD2|ensemblfungi:YML043C	psi-mi:adip_human(display_long)|uniprotkb:SSX2IP(gene name)|psi-mi:SSX2IP(display_short)|uniprotkb:KIAA0923(gene name synonym)|uniprotkb:Afadin DIL domain-interacting protein(gene name synonym)|uniprotkb:SSX2-interacting protein(gene name synonym)	psi-mi:rrn11_yeast(display_long)|uniprotkb:YM9827.09C(orf name)|uniprotkb:YML043C(locus name)|uniprotkb:RRN11(gene name)|psi-mi:RRN11(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11545783|imex:IM-24995-2474	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011538912.1|refseq:NP_001159765.1|refseq:NP_001159766.1|refseq:NP_001159767.1|refseq:NP_001159889.1|refseq:NP_054740.3|refseq:XP_005270484.1|refseq:XP_005270485.1|refseq:XP_006710394.1|refseq:XP_016855723.1|ensembl:ENSG00000117155(gene)|ensembl:ENST00000342203(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005912"(adherens junction)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031252"(cell leading edge)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0035735"(intraciliary transport involved in cilium assembly)|go:"GO:0036064"(ciliary basal body)|go:"GO:0060271"(cilium assembly)|go:"GO:2000145"(regulation of cell motility)|interpro:IPR021622|mint:Q9Y2D8|entrezgene/locuslink:117178(identity)	refseq:NP_013669.1|sgd:S000004507|dip:DIP-4542N|mint:Q04712|ensemblfungi:YML043C(gene)|ensemblfungi:YML043C_mRNA(transcript)|go:"GO:0001164"(RNA polymerase I core promoter sequence-specific DNA binding)|go:"GO:0001181"(RNA polymerase I general transcription initiation factor activity)|go:"GO:0005730"(nucleolus)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0042790"(nucleolar large rRNA transcription by RNA polymerase I)|go:"GO:0070860"(RNA polymerase I core factor complex)|interpro:IPR007224(RNA polymerase I specific initiation factor)|interpro:IPR016850(Core factor complex, Rrn11 component)|rcsb pdb:5N5Y|rcsb pdb:5N5Z|rcsb pdb:5N60|rcsb pdb:5N61|rcsb pdb:5O7X|rcsb pdb:5OA1|rcsb pdb:5W5Y|rcsb pdb:5W64|rcsb pdb:5W65|rcsb pdb:5W66|rcsb pdb:6RQH|rcsb pdb:6RQL|rcsb pdb:6RRD|rcsb pdb:6RUI|rcsb pdb:6RUO|rcsb pdb:6RWE|rcsb pdb:6TPS|sgd:YML043C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:E0VeMRF9SrpQKSJFP01XEbMjeF89606	rogid:HeXVovHQGBfbg6FbSkFO9/T64hE559292	intact-crc:6ADDC15FDC5A98B4|rigid:b6xKGsfdNTImjel1uUuhs1+q4Gs	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q04712	uniprotkb:Q9UPY8	intact:EBI-27790|uniprotkb:D6VZD2|ensemblfungi:YML043C	intact:EBI-726739|uniprotkb:O00265|uniprotkb:Q6FI15|uniprotkb:Q9BZP7|uniprotkb:Q9BZP8|uniprotkb:B7WPK5|uniprotkb:Q6FHB0|ensembl:ENSP00000233121	psi-mi:rrn11_yeast(display_long)|uniprotkb:YM9827.09C(orf name)|uniprotkb:YML043C(locus name)|uniprotkb:RRN11(gene name)|psi-mi:RRN11(display_short)	psi-mi:mare3_human(display_long)|uniprotkb:End-binding protein 3(gene name synonym)|uniprotkb:EB1 protein family member 3(gene name synonym)|uniprotkb:RP3(gene name synonym)|uniprotkb:MAPRE3(gene name)|psi-mi:MAPRE3(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11545774|imex:IM-24995-2473	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013669.1|sgd:S000004507|dip:DIP-4542N|mint:Q04712|ensemblfungi:YML043C(gene)|ensemblfungi:YML043C_mRNA(transcript)|go:"GO:0001164"(RNA polymerase I core promoter sequence-specific DNA binding)|go:"GO:0001181"(RNA polymerase I general transcription initiation factor activity)|go:"GO:0005730"(nucleolus)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0042790"(nucleolar large rRNA transcription by RNA polymerase I)|go:"GO:0070860"(RNA polymerase I core factor complex)|interpro:IPR007224(RNA polymerase I specific initiation factor)|interpro:IPR016850(Core factor complex, Rrn11 component)|rcsb pdb:5N5Y|rcsb pdb:5N5Z|rcsb pdb:5N60|rcsb pdb:5N61|rcsb pdb:5O7X|rcsb pdb:5OA1|rcsb pdb:5W5Y|rcsb pdb:5W64|rcsb pdb:5W65|rcsb pdb:5W66|rcsb pdb:6RQH|rcsb pdb:6RQL|rcsb pdb:6RRD|rcsb pdb:6RUI|rcsb pdb:6RUO|rcsb pdb:6RWE|rcsb pdb:6TPS|sgd:YML043C(identity)	refseq:NP_036458.2|refseq:XP_016859086.1|refseq:NP_001289979.1|refseq:XP_006712030.1|refseq:XP_011531002.1|dip:DIP-56069N|ensembl:ENSG00000084764(gene)|ensembl:ENST00000233121(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0008017"(microtubule binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030496"(midbody)|go:"GO:0031110"(regulation of microtubule polymerization or depolymerization)|go:"GO:0031113"(regulation of microtubule polymerization)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0042802"(identical protein binding)|go:"GO:0045737"(positive regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051233"(spindle midzone)|go:"GO:0051301"(cell division)|go:"GO:1903033"(positive regulation of microtubule plus-end binding)|go:"GO:1904825"(protein localization to microtubule plus-end)|go:"GO:1905721"(mitotic spindle astral microtubule end)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR004953(EB1, C-terminal)|interpro:IPR027328|interpro:IPR027738|interpro:IPR036133|interpro:IPR036872|mint:Q9UPY8|rcsb pdb:1WYO|rcsb pdb:3CO1|rcsb pdb:3JAK|rcsb pdb:3JAL|rcsb pdb:3JAR|rcsb pdb:3TQ7|entrezgene/locuslink:22924(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:HeXVovHQGBfbg6FbSkFO9/T64hE559292	rogid:LHuufxyNrygS3iFW5mmg13R43NE9606	intact-crc:964BA3056019DF65|rigid:EFNPljGHdNbt+95Zb2JFXjKST4A	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q04712	uniprotkb:Q96MT8-3	intact:EBI-27790|uniprotkb:D6VZD2|ensemblfungi:YML043C	intact:EBI-11522539|ensembl:ENSP00000507703|ensembl:ENSP00000328382|ensembl:ENSP00000506728|ensembl:ENSP00000506791|ensembl:ENSP00000506828|ensembl:ENSP00000507228	psi-mi:rrn11_yeast(display_long)|uniprotkb:YM9827.09C(orf name)|uniprotkb:YML043C(locus name)|uniprotkb:RRN11(gene name)|psi-mi:RRN11(display_short)	psi-mi:q96mt8-3(display_long)|uniprotkb:CEP63(gene name)|psi-mi:CEP63(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11545765|imex:IM-24995-2472	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013669.1|sgd:S000004507|dip:DIP-4542N|mint:Q04712|ensemblfungi:YML043C(gene)|ensemblfungi:YML043C_mRNA(transcript)|go:"GO:0001164"(RNA polymerase I core promoter sequence-specific DNA binding)|go:"GO:0001181"(RNA polymerase I general transcription initiation factor activity)|go:"GO:0005730"(nucleolus)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0042790"(nucleolar large rRNA transcription by RNA polymerase I)|go:"GO:0070860"(RNA polymerase I core factor complex)|interpro:IPR007224(RNA polymerase I specific initiation factor)|interpro:IPR016850(Core factor complex, Rrn11 component)|rcsb pdb:5N5Y|rcsb pdb:5N5Z|rcsb pdb:5N60|rcsb pdb:5N61|rcsb pdb:5O7X|rcsb pdb:5OA1|rcsb pdb:5W5Y|rcsb pdb:5W64|rcsb pdb:5W65|rcsb pdb:5W66|rcsb pdb:6RQH|rcsb pdb:6RQL|rcsb pdb:6RRD|rcsb pdb:6RUI|rcsb pdb:6RUO|rcsb pdb:6RWE|rcsb pdb:6TPS|sgd:YML043C(identity)	intact:EBI-741977(isoform-parent)|ensembl:ENST00000332047(transcript)|ensembl:ENST00000682042(transcript)|ensembl:ENST00000682800(transcript)|ensembl:ENST00000682858(transcript)|ensembl:ENST00000683177(transcript)|ensembl:ENST00000683861(transcript)|ensembl:ENSG00000182923(gene)|uniprotkb:Q96MT8-3(isoform-parent)|entrezgene/locuslink:80254(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:HeXVovHQGBfbg6FbSkFO9/T64hE559292	rogid:U0uvVcOCzA8Qp2cCB0ilixgd4Yc9606	intact-crc:9828F10A8C402BAF|rigid:AF4Ija845Zk96YrfkC9lGqse1sk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O95273	uniprotkb:Q04712	intact:EBI-748961|uniprotkb:A8K3Q0|uniprotkb:A8K3U2|uniprotkb:Q6ZQN9|uniprotkb:Q7Z519|uniprotkb:Q8NBS7|uniprotkb:Q8NBY2|uniprotkb:Q9NS19|uniprotkb:Q9NYH3|uniprotkb:Q9UHX9|ensembl:ENSP00000300213	intact:EBI-27790|uniprotkb:D6VZD2|ensemblfungi:YML043C	psi-mi:ccdb1_human(display_long)|uniprotkb:Grap2 and cyclin-D-interacting protein(gene name synonym)|uniprotkb:Human homolog of Maid(gene name synonym)|uniprotkb:CCNDBP1(gene name)|psi-mi:CCNDBP1(display_short)|uniprotkb:DIP1(gene name synonym)|uniprotkb:GCIP(gene name synonym)|uniprotkb:HHM(gene name synonym)	psi-mi:rrn11_yeast(display_long)|uniprotkb:YM9827.09C(orf name)|uniprotkb:YML043C(locus name)|uniprotkb:RRN11(gene name)|psi-mi:RRN11(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11545756|imex:IM-24995-2471	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_036274.3|ensembl:ENSG00000166946(gene)|ensembl:ENST00000300213(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0016604"(nuclear body)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR026907|mint:O95273|rcsb pdb:3AY5|entrezgene/locuslink:23582(identity)	refseq:NP_013669.1|sgd:S000004507|dip:DIP-4542N|mint:Q04712|ensemblfungi:YML043C(gene)|ensemblfungi:YML043C_mRNA(transcript)|go:"GO:0001164"(RNA polymerase I core promoter sequence-specific DNA binding)|go:"GO:0001181"(RNA polymerase I general transcription initiation factor activity)|go:"GO:0005730"(nucleolus)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0042790"(nucleolar large rRNA transcription by RNA polymerase I)|go:"GO:0070860"(RNA polymerase I core factor complex)|interpro:IPR007224(RNA polymerase I specific initiation factor)|interpro:IPR016850(Core factor complex, Rrn11 component)|rcsb pdb:5N5Y|rcsb pdb:5N5Z|rcsb pdb:5N60|rcsb pdb:5N61|rcsb pdb:5O7X|rcsb pdb:5OA1|rcsb pdb:5W5Y|rcsb pdb:5W64|rcsb pdb:5W65|rcsb pdb:5W66|rcsb pdb:6RQH|rcsb pdb:6RQL|rcsb pdb:6RRD|rcsb pdb:6RUI|rcsb pdb:6RUO|rcsb pdb:6RWE|rcsb pdb:6TPS|sgd:YML043C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Vi9aoFc+Mov6P3X6KGmsTxXqxvM9606	rogid:HeXVovHQGBfbg6FbSkFO9/T64hE559292	intact-crc:1E1F2D73F9F14A07|rigid:kDcumX4pkJwS3XoIcxA5QZJa6JE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q04969	uniprotkb:Q8N6L0	intact:EBI-27827|uniprotkb:D6VZB9|ensemblfungi:YML055W	intact:EBI-749265|uniprotkb:Q96MC3|ensembl:ENSP00000404220	psi-mi:spc2_yeast(display_long)|uniprotkb:YML055W(locus name)|uniprotkb:YM9958.07(orf name)|uniprotkb:SPC2(gene name)|psi-mi:SPC2(display_short)|uniprotkb:SPY1(gene name synonym)|uniprotkb:Microsomal signal peptidase subunit 2(gene name synonym)	psi-mi:kash5_human(display_long)|uniprotkb:KASH5(gene name)|psi-mi:KASH5(display_short)|uniprotkb:CCDC155(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 155(gene name synonym)|uniprotkb:KASH domain-containing protein 5(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11545801|imex:IM-24995-2476	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013657.1|sgd:S000004519|dip:DIP-4540N|mint:Q04969|ensemblfungi:YML055W(gene)|ensemblfungi:YML055W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005787"(signal peptidase complex)|go:"GO:0006465"(signal peptide processing)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045047"(protein targeting to ER)|go:"GO:0120236"(negative regulation of posttranslational protein targeting to membrane, translocation)|interpro:IPR009582(Microsomal signal peptidase 25 kDa subunit)|sgd:YML055W(identity)	refseq:NP_653289.3|ensembl:ENSG00000161609(gene)|ensembl:ENST00000447857(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034397"(telomere localization)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051225"(spindle assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0090172"(microtubule cytoskeleton organization involved in homologous chromosome segregation)|go:"GO:0090220"(chromosome localization to nuclear envelope involved in homologous chromosome segregation)|go:"GO:0090619"(meiotic spindle pole)|interpro:IPR011992(EF-Hand type)|interpro:IPR028168|interpro:IPR028170|interpro:IPR039508|mint:Q8N6L0|rcsb pdb:6R2I|rcsb pdb:6WMF|entrezgene/locuslink:147872(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:ZXf9rPA3/ryPnDqI4JGp0VMNMe4559292	rogid:Wl9L7AcvDHCZuKjYLn8QgGIbZTc9606	intact-crc:CB8401643DB9689B|rigid:400OZ0VEOZXtLA3t20J6oKxeQQQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q04712	uniprotkb:Q9Y6K9	intact:EBI-27790|uniprotkb:D6VZD2|ensemblfungi:YML043C	intact:EBI-81279|intact:EBI-356130|uniprotkb:Q7LBY6|uniprotkb:Q7Z7F1|ensembl:ENSP00000471166|ensembl:ENSP00000479662	psi-mi:rrn11_yeast(display_long)|uniprotkb:YM9827.09C(orf name)|uniprotkb:YML043C(locus name)|uniprotkb:RRN11(gene name)|psi-mi:RRN11(display_short)	psi-mi:nemo_human(display_long)|uniprotkb:IKBKG(gene name)|psi-mi:IKBKG(display_short)|uniprotkb:FIP3(gene name synonym)|uniprotkb:NEMO(gene name synonym)|uniprotkb:NF-kappa-B essential modifier(gene name synonym)|uniprotkb:Inhibitor of nuclear factor kappa-B kinase subunit gamma(gene name synonym)|uniprotkb:IkB kinase-associated protein 1(gene name synonym)|uniprotkb:FIP-3(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11545792|imex:IM-24995-2475	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013669.1|sgd:S000004507|dip:DIP-4542N|mint:Q04712|ensemblfungi:YML043C(gene)|ensemblfungi:YML043C_mRNA(transcript)|go:"GO:0001164"(RNA polymerase I core promoter sequence-specific DNA binding)|go:"GO:0001181"(RNA polymerase I general transcription initiation factor activity)|go:"GO:0005730"(nucleolus)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0042790"(nucleolar large rRNA transcription by RNA polymerase I)|go:"GO:0070860"(RNA polymerase I core factor complex)|interpro:IPR007224(RNA polymerase I specific initiation factor)|interpro:IPR016850(Core factor complex, Rrn11 component)|rcsb pdb:5N5Y|rcsb pdb:5N5Z|rcsb pdb:5N60|rcsb pdb:5N61|rcsb pdb:5O7X|rcsb pdb:5OA1|rcsb pdb:5W5Y|rcsb pdb:5W64|rcsb pdb:5W65|rcsb pdb:5W66|rcsb pdb:6RQH|rcsb pdb:6RQL|rcsb pdb:6RRD|rcsb pdb:6RUI|rcsb pdb:6RUO|rcsb pdb:6RWE|rcsb pdb:6TPS|sgd:YML043C(identity)	refseq:NP_001308325.1|refseq:NP_001308326.1|refseq:NP_001093326.2|refseq:NP_001093327.1|refseq:NP_001138727.1|refseq:NP_003630.1|dip:DIP-27528N|ensembl:ENSG00000269335(gene)|ensembl:ENST00000594239(transcript)|ensembl:ENST00000611071(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0008385"(IkappaB kinase complex)|go:"GO:0009615"(response to virus)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043276"(anoikis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050862"(positive regulation of T cell receptor signaling pathway)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051650"(establishment of vesicle localization)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1990450"(linear polyubiquitin binding)|go:"GO:1990459"(transferrin receptor binding)|interpro:IPR021063|interpro:IPR032419|interpro:IPR034735|mint:Q9Y6K9|rcsb pdb:2JVX|rcsb pdb:2JVY|rcsb pdb:3BRT|rcsb pdb:3BRV|rcsb pdb:3CL3|rcsb pdb:3FX0|rcsb pdb:4BWN|rcsb pdb:5AAY|rcsb pdb:5LDE|rcsb pdb:6MI3|rcsb pdb:6MI4|rcsb pdb:6YEK|reactome:R-HSA-1169091|reactome:R-HSA-1236974|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-1810476|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-4755510|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5602636|reactome:R-HSA-5603027|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5684264|reactome:R-HSA-5689880|reactome:R-HSA-5689896|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-933543|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-975144|entrezgene/locuslink:8517(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:HeXVovHQGBfbg6FbSkFO9/T64hE559292	rogid:9OeZIMeJvNtDEMoiLaKwVEpxSSM9606	intact-crc:F99E6FE7C29D9A42|rigid:Yb0h9SnRLz93S+simkWtrCpcYQg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96BA8	uniprotkb:Q04969	intact:EBI-6942903|ensembl:ENSP00000481956|intact:MINT-268046|intact:MINT-8162577|uniprotkb:Q8N2D5|uniprotkb:Q96CP0	intact:EBI-27827|uniprotkb:D6VZB9|ensemblfungi:YML055W	psi-mi:cr3l1_human(display_long)|uniprotkb:CREB3L1(gene name)|psi-mi:CREB3L1(display_short)|uniprotkb:OASIS(gene name synonym)|uniprotkb:PSEC0238(orf name)|uniprotkb:Old astrocyte specifically-induced substance(gene name synonym)	psi-mi:spc2_yeast(display_long)|uniprotkb:YML055W(locus name)|uniprotkb:YM9958.07(orf name)|uniprotkb:SPC2(gene name)|psi-mi:SPC2(display_short)|uniprotkb:SPY1(gene name synonym)|uniprotkb:Microsomal signal peptidase subunit 2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11545810|imex:IM-24995-2477	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157613(gene)|ensembl:ENST00000621158(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0070278"(extracellular matrix constituent secretion)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029805|mint:Q96BA8|reactome:R-HSA-8874211|refseq:NP_443086.1|entrezgene/locuslink:90993(identity)	refseq:NP_013657.1|sgd:S000004519|dip:DIP-4540N|mint:Q04969|ensemblfungi:YML055W(gene)|ensemblfungi:YML055W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005787"(signal peptidase complex)|go:"GO:0006465"(signal peptide processing)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045047"(protein targeting to ER)|go:"GO:0120236"(negative regulation of posttranslational protein targeting to membrane, translocation)|interpro:IPR009582(Microsomal signal peptidase 25 kDa subunit)|sgd:YML055W(identity)	-	comment:mint|function:"Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE"	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:sMWUFmBeBBCO+T0Y2CuB/un1lBg9606	rogid:ZXf9rPA3/ryPnDqI4JGp0VMNMe4559292	intact-crc:AB4AAB0323EB4363|rigid:4iUkH+SMctTR3eWg5hEqFhhupzc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q05164	uniprotkb:G5E962	intact:EBI-31733|uniprotkb:Q08294|uniprotkb:D6W1R6|ensemblfungi:YOL155C	intact:EBI-11525615|ensembl:ENSP00000328177	psi-mi:hpf1_yeast(display_long)|uniprotkb:HPF1(gene name)|psi-mi:HPF1(display_short)|uniprotkb:AOF1001(orf name)|uniprotkb:YOL155C(locus name)	psi-mi:g5e962_human(display_long)|uniprotkb:hCG_1644200(orf name)|uniprotkb:MAGEA11(gene name)|psi-mi:MAGEA11(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11545847|imex:IM-24995-2481	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005515|refseq:NP_014487.1|interpro:IPR021031|mint:Q05164|ensemblfungi:YOL155C(gene)|ensemblfungi:YOL155C_mRNA(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0009277"(fungal-type cell wall)|go:"GO:0015926"(glucosidase activity)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0071944"(cell periphery)|reactome:R-SCE-983168|sgd:YOL155C(identity)	refseq:NP_001011544.1|ensembl:ENSG00000185247(gene)|ensembl:ENST00000333104(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016604"(nuclear body)|interpro:IPR002190(MAGE protein)|interpro:IPR021072|interpro:IPR030099|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|entrezgene/locuslink:4110(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:6bUWFxCsumvuNKLLVzCUfBbL1hA559292	rogid:sVB0aA6yibWUx/d2SE+pwpKKgtI9606	intact-crc:E168375FECFF887F|rigid:MrtZO7x5n7XkNf1XvaUun1iGWrU	false	-	sufficient binding region:82-400	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q53G59	uniprotkb:Q05021	intact:EBI-740929|ensembl:ENSP00000356230|uniprotkb:A6NEN8|uniprotkb:B7Z7B8|uniprotkb:Q9HBX5	intact:EBI-27490|uniprotkb:D6W052|ensemblfungi:YMR227C	psi-mi:klh12_human(display_long)|uniprotkb:CUL3-interacting protein 1(gene name synonym)|uniprotkb:KLHL12(gene name)|psi-mi:KLHL12(display_short)|uniprotkb:C3IP1(gene name synonym)|uniprotkb:DKIR homolog(gene name synonym)	psi-mi:taf7_yeast(display_long)|uniprotkb:TAF7(gene name)|psi-mi:TAF7(display_short)|uniprotkb:TAF67(gene name synonym)|uniprotkb:YMR227C(locus name)|uniprotkb:YM9959.09C(orf name)|uniprotkb:TBP-associated factor 7(gene name synonym)|uniprotkb:TBP-associated factor 67 kDa(gene name synonym)|uniprotkb:TAFII-67(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11545838|imex:IM-24995-2480	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048208"(COPII vesicle coating)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR017096(Kelch-like protein, gigaxonin)|mint:Q53G59|rcsb pdb:2VPJ|rcsb pdb:6TTK|rcsb pdb:6V7O|reactome:R-HSA-4641258|refseq:NP_067646.1|ensembl:ENSG00000117153(gene)|ensembl:ENST00000367261(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0014029"(neural crest formation)|go:"GO:0014032"(neural crest cell development)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0034451"(centriolar satellite)|refseq:NP_001289980.1|refseq:NP_001290038.1|entrezgene/locuslink:59349(identity)	mint:Q05021|refseq:NP_013954.1|sgd:S000004840|dip:DIP-6818N|ensemblfungi:YMR227C(gene)|ensemblfungi:YMR227C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|interpro:IPR006751(TAFII55 protein conserved region)|interpro:IPR037817|rcsb pdb:4OY2|reactome:R-SCE-674695|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-76042|sgd:YMR227C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:C4I/Ys9vqNqfG61HsXRZhywP4vE9606	rogid:VrnziwJxWKBtVBnyE3cijExq6/0559292	intact-crc:8799F2242BCA0525|rigid:cpfrkul7pqqF7qDfIyZG1amofRI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q04978	uniprotkb:Q8TAP6	intact:EBI-27823|uniprotkb:D6VZC2|ensemblfungi:YML053C	intact:EBI-742887|ensembl:ENSP00000262127|uniprotkb:Q658N5|uniprotkb:Q9H9U7|uniprotkb:B0YJB2|uniprotkb:B4DXG5|uniprotkb:B4DZW1	psi-mi:ymf3_yeast(display_long)|uniprotkb:YM9958.09C(orf name)|uniprotkb:YML053C(locus name)	psi-mi:cep76_human(display_long)|uniprotkb:CEP76(gene name)|psi-mi:CEP76(display_short)|uniprotkb:C18orf9(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11545829|imex:IM-24995-2479	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000004517|refseq:NP_013659.1|dip:DIP-1950N|ensemblfungi:YML053C(gene)|ensemblfungi:YML053C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|sgd:YML053C(identity)	refseq:NP_079175.2|ensembl:ENSG00000101624(gene)|ensembl:ENST00000262127(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0046599"(regulation of centriole replication)|interpro:IPR028926|interpro:IPR038765|mint:Q8TAP6|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_001258918.1|entrezgene/locuslink:79959(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:eYvLCLQP+e6HSEiAjDeWkJBUCTU559292	rogid:fWzb8oIU35oVWomyDrf8u5sbxUk9606	intact-crc:A6626EB96C400627|rigid:Q71mEizYAeqEhHQP4PwKyLKNgpc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O60684	uniprotkb:Q04978	intact:EBI-359923|uniprotkb:Q5VVU3|uniprotkb:B2RDC7|ensembl:ENSP00000362728|uniprotkb:D3DPP5	intact:EBI-27823|uniprotkb:D6VZC2|ensemblfungi:YML053C	psi-mi:ima7_human(display_long)|uniprotkb:KPNA6(gene name)|psi-mi:KPNA6(display_short)|uniprotkb:IPOA7(gene name synonym)|uniprotkb:Karyopherin subunit alpha-6(gene name synonym)	psi-mi:ymf3_yeast(display_long)|uniprotkb:YM9958.09C(orf name)|uniprotkb:YML053C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11545820|imex:IM-24995-2478	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_036448.1|ensembl:ENSG00000025800(gene)|ensembl:ENST00000373625(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0016020"(membrane)|go:"GO:0019079"(viral genome replication)|go:"GO:0030682"(mitigation of host defenses by symbiont)|go:"GO:0043657"(host cell)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060135"(maternal process involved in female pregnancy)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0075506"(entry of viral genome into host nucleus through nuclear pore complex via importin)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:1903902"(positive regulation of viral life cycle)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|mint:O60684|rcsb pdb:4UAD|dip:DIP-27609N|entrezgene/locuslink:23633(identity)	sgd:S000004517|refseq:NP_013659.1|dip:DIP-1950N|ensemblfungi:YML053C(gene)|ensemblfungi:YML053C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|sgd:YML053C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:3NsSIcE6BHIqYlvfGRolUKD/5uc9606	rogid:eYvLCLQP+e6HSEiAjDeWkJBUCTU559292	intact-crc:66416F9B96310164|rigid:GpHakCsqlndyZ6pH+os8y4W+2WU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O43765	uniprotkb:Q05899	intact:EBI-347996|ensembl:ENSP00000221566|ensembl:ENSP00000503397|ensembl:ENSP00000504495|uniprotkb:Q9BTZ9|intact:EBI-1045243|uniprotkb:Q6FIA9|uniprotkb:D6W610	intact:EBI-33462|uniprotkb:D6VYU1|ensemblfungi:YLR297W	psi-mi:sgta_human(display_long)|uniprotkb:SGTA(gene name)|psi-mi:SGTA(display_short)|uniprotkb:SGT(gene name synonym)|uniprotkb:Alpha-SGT(gene name synonym)|uniprotkb:Vpu-binding protein(gene name synonym)|uniprotkb:SGT1(gene name synonym)	psi-mi:yl297_yeast(display_long)|uniprotkb:YLR297W(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11545885|imex:IM-24995-2485	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:4CPG|rcsb pdb:4GOD|rcsb pdb:4GOE|rcsb pdb:4GOF|reactome:R-HSA-9609523|rcsb pdb:2VYI|ensembl:ENSG00000104969(gene)|ensembl:ENST00000221566(transcript)|ensembl:ENST00000676943(transcript)|ensembl:ENST00000677149(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072380"(TRC complex)|go:"GO:0098850"(extrinsic component of synaptic vesicle membrane)|go:"GO:1903070"(negative regulation of ER-associated ubiquitin-dependent protein catabolic process)|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)|go:"GO:1903646"(positive regulation of chaperone-mediated protein folding)|go:"GO:1904288"(BAT3 complex binding)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR032374|mint:O43765|refseq:XP_011526480.1|refseq:NP_003012.1|entrezgene/locuslink:6449(identity)	sgd:S000004288|refseq:NP_013400.1|dip:DIP-4684N|ensemblfungi:YLR297W(gene)|ensemblfungi:YLR297W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016021"(integral component of membrane)|sgd:YLR297W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:r/Cyj4UJk/cS8QdrbjhTZMPCigI9606	rogid:5NnJTt1UJw0+xxbJS5roF36sLGI559292	intact-crc:E19CE75562989487|rigid:0yAmIuTTO1UefLVVsZaLO9S1Hs0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q05637	uniprotkb:Q9UI14	intact:EBI-37326|uniprotkb:D6VSR1|ensemblfungi:YDR281C	intact:EBI-712367|ensembl:ENSP00000222008|uniprotkb:Q7Z4Y2|uniprotkb:Q9Y3R1	psi-mi:phm6_yeast(display_long)|uniprotkb:PHM6(gene name)|psi-mi:PHM6(display_short)|uniprotkb:D9954.14(orf name)|uniprotkb:YDR281C(locus name)	psi-mi:praf1_human(display_long)|uniprotkb:PRA1 family protein 1(gene name synonym)|uniprotkb:RABAC1(gene name)|psi-mi:RABAC1(display_short)|uniprotkb:PRA1(gene name synonym)|uniprotkb:PRAF1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11545876|imex:IM-24995-2484	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002689|refseq:NP_010567.1|dip:DIP-4775N|ensemblfungi:YDR281C(gene)|ensemblfungi:YDR281C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0016021"(integral component of membrane)|sgd:YDR281C(identity)	refseq:NP_006414.2|ensembl:ENSG00000105404(gene)|ensembl:ENST00000222008(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0070064"(proline-rich region binding)|interpro:IPR004895(Prenylated rab acceptor PRA1)|mint:Q9UI14|entrezgene/locuslink:10567(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:4CXswPUeUtOazQ3jQAWOO1E96Lg559292	rogid:WS2rUY7yXRbR7pqWgfUCbnEiDbg9606	intact-crc:84B824090A54DE80|rigid:2WjLcCnzVfgd0x11TZ7gu507FkI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96DZ9-2	uniprotkb:Q05515	intact:EBI-11522780|ensembl:ENSP00000352270|ensembl:ENSP00000497215	intact:EBI-38400|uniprotkb:D6VSX6|ensemblfungi:YDR346C	psi-mi:q96dz9-2(display_long)|uniprotkb:CMTM5(gene name)|psi-mi:CMTM5(display_short)|uniprotkb:CKLFSF5(gene name synonym)|uniprotkb:Chemokine-like factor superfamily member 5(gene name synonym)	psi-mi:svf1_yeast(display_long)|uniprotkb:SVF1(gene name)|psi-mi:SVF1(display_short)|uniprotkb:SGI1(gene name synonym)|uniprotkb:YDR346C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11545867|imex:IM-24995-2483	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000166091(gene)|ensembl:ENST00000359320(transcript)|ensembl:ENST00000649278(transcript)|intact:EBI-2548702(isoform-parent)|uniprotkb:Q96DZ9-2(isoform-parent)|entrezgene/locuslink:116173(identity)	sgd:S000002754|refseq:NP_010633.3|mint:Q05515|dip:DIP-5243N|ensemblfungi:YDR346C(gene)|ensemblfungi:YDR346C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0034599"(cellular response to oxidative stress)|interpro:IPR013931(Oxidative stress survival, Svf1-like)|interpro:IPR033394|sgd:YDR346C(identity)	-	-	crc64:926A28FE140F87A5	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:2TJ7rZKQNb5hH5gz9i+ujOEOIOg9606	rogid:K9DLW9y+JFX3NTUKWKHVb/YpPVg559292	intact-crc:0893D27BD11355D3|rigid:cHfqz9yeOR0kWYXEyZ1Kfja6aYE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O43791	uniprotkb:Q05164	intact:EBI-743549|uniprotkb:Q53HJ1|uniprotkb:B2R6S3|uniprotkb:D3DTW7|ensembl:ENSP00000240327|ensembl:ENSP00000377001|ensembl:ENSP00000420908|ensembl:ENSP00000424119|ensembl:ENSP00000425905|ensembl:ENSP00000426986|ensembl:ENSP00000499562	intact:EBI-31733|uniprotkb:Q08294|uniprotkb:D6W1R6|ensemblfungi:YOL155C	psi-mi:spop_human(display_long)|uniprotkb:HIB homolog 1(gene name synonym)|uniprotkb:Roadkill homolog 1(gene name synonym)|uniprotkb:SPOP(gene name)|psi-mi:SPOP(display_short)	psi-mi:hpf1_yeast(display_long)|uniprotkb:HPF1(gene name)|psi-mi:HPF1(display_short)|uniprotkb:AOF1001(orf name)|uniprotkb:YOL155C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11545858|imex:IM-24995-2482	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001007227.1|refseq:NP_001007228.1|refseq:NP_001007229.1|refseq:NP_001007230.1|refseq:NP_001007231.1|refseq:NP_003554.1|refseq:XP_005257780.1|refseq:XP_005257781.1|ensembl:ENSG00000121067(gene)|ensembl:ENST00000347630(transcript)|ensembl:ENST00000393328(transcript)|ensembl:ENST00000503676(transcript)|ensembl:ENST00000504102(transcript)|ensembl:ENST00000509079(transcript)|ensembl:ENST00000514121(transcript)|ensembl:ENST00000665825(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0016607"(nuclear speck)|go:"GO:0030162"(regulation of proteolysis)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR034089|mint:O43791|rcsb pdb:2CR2|rcsb pdb:3HQH|rcsb pdb:3HQI|rcsb pdb:3HQL|rcsb pdb:3HQM|rcsb pdb:3HSV|rcsb pdb:3HTM|rcsb pdb:3HU6|rcsb pdb:3IVB|rcsb pdb:3IVQ|rcsb pdb:3IVV|rcsb pdb:4EOZ|rcsb pdb:4HS2|rcsb pdb:4J8Z|rcsb pdb:4O1V|rcsb pdb:6F8F|rcsb pdb:6F8G|rcsb pdb:6I41|rcsb pdb:6I5P|rcsb pdb:6I68|rcsb pdb:6I7A|rcsb pdb:7D3D|rcsb pdb:7LIN|rcsb pdb:7LIO|rcsb pdb:7LIP|rcsb pdb:7LIQ|reactome:R-HSA-5632684|go:"GO:0005634"(nucleus)|refseq:XP_016880693.1|dip:DIP-50517N|entrezgene/locuslink:8405(identity)	sgd:S000005515|refseq:NP_014487.1|interpro:IPR021031|mint:Q05164|ensemblfungi:YOL155C(gene)|ensemblfungi:YOL155C_mRNA(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0009277"(fungal-type cell wall)|go:"GO:0015926"(glucosidase activity)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0071944"(cell periphery)|reactome:R-SCE-983168|sgd:YOL155C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:PC9ofpvk14xwTnnqT590/YRnx/49606	rogid:6bUWFxCsumvuNKLLVzCUfBbL1hA559292	intact-crc:CCCE326B875BC4C3|rigid:LtppZUYycnOgqRhpbMJVkBufiRg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q06011	uniprotkb:Q8N9N5-2	intact:EBI-36392|uniprotkb:D6VZ25|ensemblfungi:YLR390W	intact:EBI-11524452|ensembl:ENSP00000347125	psi-mi:ecm19_yeast(display_long)|uniprotkb:ECM19(gene name)|psi-mi:ECM19(display_short)|uniprotkb:Extracellular mutant protein 19(gene name synonym)|uniprotkb:YLR390W(locus name)	psi-mi:q8n9n5-2(display_long)|uniprotkb:BANP(gene name)|psi-mi:BANP(display_short)|uniprotkb:BEN domain-containing protein 1(gene name synonym)|uniprotkb:BEND1(gene name synonym)|uniprotkb:Btg3-associated nuclear protein(gene name synonym)|uniprotkb:SMAR1(gene name synonym)|uniprotkb:Scaffold/matrix-associated region-1-binding protein(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11545921|imex:IM-24995-2489	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000004382|refseq:NP_013494.3|dip:DIP-8813N|ensemblfungi:YLR390W(gene)|ensemblfungi:YLR390W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0071555"(cell wall organization)|sgd:YLR390W(identity)	ensembl:ENSG00000172530(gene)|ensembl:ENST00000355022(transcript)|intact:EBI-744695(isoform-parent)|uniprotkb:Q8N9N5-2(isoform-parent)|entrezgene/locuslink:54971(identity)	-	crc64:B469042AC2025AA7	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:UBC9QbTkaTXXDvZdA/6/HJWDVqM559292	rogid:ESe6iCAhvq+i57fQHz3rGyg6UOo9606	intact-crc:71DF53C887EA4482|rigid:XAelBa76R8A2YR1Ckv+C/lnQi1I	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38432	uniprotkb:Q05955	intact:EBI-945751|uniprotkb:B2R931|ensembl:ENSP00000240316	intact:EBI-34541|uniprotkb:D6VYM7|ensemblfungi:YLR227C	psi-mi:coil_human(display_long)|uniprotkb:COIL(gene name)|psi-mi:COIL(display_short)|uniprotkb:CLN80(gene name synonym)|uniprotkb:p80-coilin(gene name synonym)	psi-mi:ady4_yeast(display_long)|uniprotkb:ADY4(gene name)|psi-mi:ADY4(display_short)|uniprotkb:L8083.11(orf name)|uniprotkb:YLR227C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11545912|imex:IM-24995-2488	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004636.1|dip:DIP-38503N|ensembl:ENSG00000121058(gene)|ensembl:ENST00000240316(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0015030"(Cajal body)|go:"GO:0016020"(membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0030619"(U1 snRNA binding)|go:"GO:0030620"(U2 snRNA binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR024822|interpro:IPR031722|mint:P38432|entrezgene/locuslink:8161(identity)	sgd:S000004217|refseq:NP_013328.1|dip:DIP-4786N|ensemblfungi:YLR227C(gene)|ensemblfungi:YLR227C_mRNA(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0030437"(ascospore formation)|go:"GO:0035974"(meiotic spindle pole body)|go:"GO:0051301"(cell division)|sgd:YLR227C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:hd5p6AbyA/GYNEeca99Mdb41qM09606	rogid:rYFhfauuzO793SGutv2Pee7hcBM559292	intact-crc:7F70FD11102EEA3C|rigid:KMN+QdDdGOjToCWKTuBn3QggNs0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q05947	uniprotkb:P49760-3	intact:EBI-33647|uniprotkb:D6VYM4|ensemblfungi:YLR224W	intact:EBI-11535445|ensembl:ENSP00000354856|ensembl:ENSP00000459461	psi-mi:ucc1_yeast(display_long)|uniprotkb:UCC1(gene name)|psi-mi:UCC1(display_short)|uniprotkb:Ubiquitination of citrate synthase in the glyoxylate cycle protein 1(gene name synonym)|uniprotkb:YLR224W(locus name)	psi-mi:p49760-3(display_long)|uniprotkb:CDC-like kinase 2(gene name synonym)|uniprotkb:CLK2(gene name)|psi-mi:CLK2(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11545903|imex:IM-24995-2487	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000004214|refseq:NP_013325.1|mint:Q05947|dip:DIP-1630N|ensemblfungi:YLR224W(gene)|ensemblfungi:YLR224W_mRNA(transcript)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0071406"(cellular response to methylmercury)|sgd:YLR224W(identity)	intact:EBI-750020(isoform-parent)|ensembl:ENSG00000176444(gene)|ensembl:ENSG00000261893(gene)|ensembl:ENST00000361168(transcript)|ensembl:ENST00000572269(transcript)|uniprotkb:P49760-3(isoform-parent)|entrezgene/locuslink:1196(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:HOR8NxxNEa6zV2RmL1mMWrvNfEk559292	rogid:wFw4PjPFbFOw5k9Fqay3nAen8ZI9606	intact-crc:39005C164F6FA0F7|rigid:dM41zON6cboSe/Qro4ldVJD1YVw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q05899	uniprotkb:Q99614	intact:EBI-33462|uniprotkb:D6VYU1|ensemblfungi:YLR297W	intact:EBI-742074|uniprotkb:Q9BVT3|uniprotkb:B2RCT2|uniprotkb:D3DQJ8|ensembl:ENSP00000231238|ensembl:ENSP00000429225|ensembl:ENSP00000507891	psi-mi:yl297_yeast(display_long)|uniprotkb:YLR297W(locus name)	psi-mi:ttc1_human(display_long)|uniprotkb:TTC1(gene name)|psi-mi:TTC1(display_short)|uniprotkb:TPR1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11545894|imex:IM-24995-2486	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000004288|refseq:NP_013400.1|dip:DIP-4684N|ensemblfungi:YLR297W(gene)|ensemblfungi:YLR297W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016021"(integral component of membrane)|sgd:YLR297W(identity)	refseq:NP_001269429.1|refseq:NP_003305.1|ensembl:ENST00000231238(transcript)|ensembl:ENST00000522793(transcript)|ensembl:ENST00000682719(transcript)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|ensembl:ENSG00000113312(gene)|entrezgene/locuslink:7265(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:5NnJTt1UJw0+xxbJS5roF36sLGI559292	rogid:jpDASWCrto0zMhBm3Cj9aDQURm09606	intact-crc:3B6E553DE45D2D51|rigid:EBQypxPb9QJrQeke+M9gnc/IFBo	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q53G59	uniprotkb:Q06132	intact:EBI-740929|ensembl:ENSP00000356230|uniprotkb:A6NEN8|uniprotkb:B7Z7B8|uniprotkb:Q9HBX5	intact:EBI-34377|uniprotkb:D6VYX6|ensemblfungi:YLR336C	psi-mi:klh12_human(display_long)|uniprotkb:CUL3-interacting protein 1(gene name synonym)|uniprotkb:KLHL12(gene name)|psi-mi:KLHL12(display_short)|uniprotkb:C3IP1(gene name synonym)|uniprotkb:DKIR homolog(gene name synonym)	psi-mi:sgd1_yeast(display_long)|uniprotkb:SGD1(gene name)|psi-mi:SGD1(display_short)|uniprotkb:YLR336C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11545957|imex:IM-24995-2493	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048208"(COPII vesicle coating)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR017096(Kelch-like protein, gigaxonin)|mint:Q53G59|rcsb pdb:2VPJ|rcsb pdb:6TTK|rcsb pdb:6V7O|reactome:R-HSA-4641258|refseq:NP_067646.1|ensembl:ENSG00000117153(gene)|ensembl:ENST00000367261(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0014029"(neural crest formation)|go:"GO:0014032"(neural crest cell development)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0034451"(centriolar satellite)|refseq:NP_001289980.1|refseq:NP_001290038.1|entrezgene/locuslink:59349(identity)	refseq:NP_013440.1|sgd:S000004328|mint:Q06132|dip:DIP-6333N|ensemblfungi:YLR336C(gene)|ensemblfungi:YLR336C_mRNA(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0006972"(hyperosmotic response)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0097078"(FAL1-SGD1 complex)|interpro:IPR003890(MIF4G-like, type 3)|interpro:IPR003891(Initiation factor eIF-4 gamma, MA3)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR016024(Armadillo-type fold)|sgd:YLR336C(identity)	-	-	crc64:8EEFDB8258407FF3	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:C4I/Ys9vqNqfG61HsXRZhywP4vE9606	rogid:FxZCxGejbcvEs/J2h1HEaWeVZLQ559292	intact-crc:6C9112658267CF67|rigid:uwuWNIj20Jz1K9Kbhna+kcAp4Ks	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q06132	uniprotkb:P51116	intact:EBI-34377|uniprotkb:D6VYX6|ensemblfungi:YLR336C	intact:EBI-740459|uniprotkb:Q8WUM2|uniprotkb:Q86V09|uniprotkb:B2R9M2|uniprotkb:D3DTQ1|ensembl:ENSP00000250113	psi-mi:sgd1_yeast(display_long)|uniprotkb:SGD1(gene name)|psi-mi:SGD1(display_short)|uniprotkb:YLR336C(locus name)	psi-mi:fxr2_human(display_long)|uniprotkb:FXR2(gene name)|psi-mi:FXR2(display_short)|uniprotkb:FMR1L2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11545948|imex:IM-24995-2492	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013440.1|sgd:S000004328|mint:Q06132|dip:DIP-6333N|ensemblfungi:YLR336C(gene)|ensemblfungi:YLR336C_mRNA(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0006972"(hyperosmotic response)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0097078"(FAL1-SGD1 complex)|interpro:IPR003890(MIF4G-like, type 3)|interpro:IPR003891(Initiation factor eIF-4 gamma, MA3)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR016024(Armadillo-type fold)|sgd:YLR336C(identity)	interpro:IPR004087(K Homology)|refseq:NP_004851.2|ensembl:ENSG00000129245(gene)|ensembl:ENST00000250113(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0044326"(dendritic spine neck)|go:"GO:0045182"(translation regulator activity)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0098793"(presynapse)|go:"GO:1902737"(dendritic filopodium)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|interpro:IPR004088(K Homology, type 1)|interpro:IPR008395(Agenet)|interpro:IPR022034|interpro:IPR032172|interpro:IPR036612|interpro:IPR040148|interpro:IPR040472|interpro:IPR041560|mint:P51116|rcsb pdb:3H8Z|entrezgene/locuslink:9513(identity)	-	crc64:8EEFDB8258407FF3	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:FxZCxGejbcvEs/J2h1HEaWeVZLQ559292	rogid:NnYgyzD2NRGIO1ZHukr5qy44qRE9606	intact-crc:D5514A29E74555E1|rigid:xnbyTlAhgT+HBCSkbj2gfqWlCOw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38432	uniprotkb:Q06132	intact:EBI-945751|uniprotkb:B2R931|ensembl:ENSP00000240316	intact:EBI-34377|uniprotkb:D6VYX6|ensemblfungi:YLR336C	psi-mi:coil_human(display_long)|uniprotkb:COIL(gene name)|psi-mi:COIL(display_short)|uniprotkb:CLN80(gene name synonym)|uniprotkb:p80-coilin(gene name synonym)	psi-mi:sgd1_yeast(display_long)|uniprotkb:SGD1(gene name)|psi-mi:SGD1(display_short)|uniprotkb:YLR336C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11545939|imex:IM-24995-2491	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004636.1|dip:DIP-38503N|ensembl:ENSG00000121058(gene)|ensembl:ENST00000240316(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0015030"(Cajal body)|go:"GO:0016020"(membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0030619"(U1 snRNA binding)|go:"GO:0030620"(U2 snRNA binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR024822|interpro:IPR031722|mint:P38432|entrezgene/locuslink:8161(identity)	refseq:NP_013440.1|sgd:S000004328|mint:Q06132|dip:DIP-6333N|ensemblfungi:YLR336C(gene)|ensemblfungi:YLR336C_mRNA(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0006972"(hyperosmotic response)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0097078"(FAL1-SGD1 complex)|interpro:IPR003890(MIF4G-like, type 3)|interpro:IPR003891(Initiation factor eIF-4 gamma, MA3)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR016024(Armadillo-type fold)|sgd:YLR336C(identity)	-	-	crc64:8EEFDB8258407FF3	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:hd5p6AbyA/GYNEeca99Mdb41qM09606	rogid:FxZCxGejbcvEs/J2h1HEaWeVZLQ559292	intact-crc:5495FEBA0F3925E4|rigid:SO7As3jx3AzOgXxsft8fizVioPE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q6UN15	uniprotkb:Q06102	intact:EBI-1021914|uniprotkb:Q0VGE0|uniprotkb:Q499Y4|uniprotkb:Q49AU3|uniprotkb:Q7Z608|uniprotkb:Q8WVN3|uniprotkb:Q96F80|uniprotkb:Q9H077|intact:EBI-11535474|ensembl:ENSP00000336752|uniprotkb:B4DIR3|uniprotkb:G3XAD6	intact:EBI-38049|uniprotkb:D6W4A5|ensemblfungi:YPR107C	psi-mi:fip1_human(display_long)|uniprotkb:Factor interacting with PAP(gene name synonym)|uniprotkb:FIP1-like 1 protein(gene name synonym)|uniprotkb:Rearranged in hypereosinophilia(gene name synonym)|uniprotkb:FIP1L1(gene name)|psi-mi:FIP1L1(display_short)|uniprotkb:FIP1(gene name synonym)|uniprotkb:RHE(gene name synonym)	psi-mi:yth1_yeast(display_long)|uniprotkb:Yeast 30 kDa homolog 1(gene name synonym)|uniprotkb:YTH1(gene name)|psi-mi:YTH1(display_short)|uniprotkb:YPR107C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11545930|imex:IM-24995-2490	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000306932|ensembl:ENSP00000302993|ensembl:ENSP00000336752|ensembl:ENST00000358575|ensembl:ENSP00000351383|ensembl:ENST00000507922|ensembl:ENSP00000425456|refseq:NP_001128409.1|refseq:NP_001128410.1|refseq:NP_112179.2|ensembl:ENSG00000145216(gene)|ensembl:ENST00000337488(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|interpro:IPR007854(Fip1)|mint:Q6UN15|rcsb pdb:7K95|reactome:R-HSA-159231|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-77595|reactome:R-HSA-9673766|dip:DIP-42503N|entrezgene/locuslink:81608(identity)	refseq:NP_015432.1|sgd:S000006311|mint:Q06102|dip:DIP-2028N|ensemblfungi:YPR107C(gene)|ensemblfungi:YPR107C_mRNA(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR036855|rcsb pdb:6EOJ|reactome:R-SCE-77595|sgd:YPR107C(identity)	-	-	crc64:79C5993AE4E670EA	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/16	rogid:41uK1l8RV99q4k4Z7K9zeG3TJHA9606	rogid:rqNO3dAJtktR7RuM1ADpb9Nt0X8559292	intact-crc:8DABEF00F0C6594F|rigid:fqElL4slW+Vuhpf1giO1nOAZ3po	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96MF2	uniprotkb:Q06132	intact:EBI-745680|uniprotkb:B4DUK9|uniprotkb:Q96HU5|ensembl:ENSP00000329200	intact:EBI-34377|uniprotkb:D6VYX6|ensemblfungi:YLR336C	psi-mi:stac3_human(display_long)|uniprotkb:STAC3(gene name)|psi-mi:STAC3(display_short)	psi-mi:sgd1_yeast(display_long)|uniprotkb:SGD1(gene name)|psi-mi:SGD1(display_short)|uniprotkb:YLR336C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11545984|imex:IM-24995-2496	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001273185.1|refseq:NP_001273186.1|refseq:NP_659501.1|refseq:XP_011536428.1|ensembl:ENSG00000185482(gene)|ensembl:ENST00000332782(transcript)|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0030315"(T-tubule)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:1901387"(positive regulation of voltage-gated calcium channel activity)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|interpro:IPR001452(Src homology-3)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR035736|interpro:IPR036028|interpro:IPR039688|mint:Q96MF2|rcsb pdb:2DB6|rcsb pdb:6B29|rcsb pdb:6UY7|rcsb pdb:6UY8|rcsb pdb:6UY9|entrezgene/locuslink:246329(identity)	refseq:NP_013440.1|sgd:S000004328|mint:Q06132|dip:DIP-6333N|ensemblfungi:YLR336C(gene)|ensemblfungi:YLR336C_mRNA(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0006972"(hyperosmotic response)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0097078"(FAL1-SGD1 complex)|interpro:IPR003890(MIF4G-like, type 3)|interpro:IPR003891(Initiation factor eIF-4 gamma, MA3)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR016024(Armadillo-type fold)|sgd:YLR336C(identity)	-	-	crc64:8EEFDB8258407FF3	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:PzyVrp74OzLhtbODzinH5fHSGRc9606	rogid:FxZCxGejbcvEs/J2h1HEaWeVZLQ559292	intact-crc:E599261FDFADC441|rigid:cHruQ2Bu9L+amyG30Q0+EETJouQ	false	sufficient binding region:40-364	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q06132	uniprotkb:Q96BR9	intact:EBI-34377|uniprotkb:D6VYX6|ensemblfungi:YLR336C	intact:EBI-742740|uniprotkb:Q8IUL5|uniprotkb:Q8IWR9|uniprotkb:Q8N2Y5|uniprotkb:Q96BX0|ensembl:ENSP00000362609	psi-mi:sgd1_yeast(display_long)|uniprotkb:SGD1(gene name)|psi-mi:SGD1(display_short)|uniprotkb:YLR336C(locus name)	psi-mi:zbt8a_human(display_long)|uniprotkb:ZBTB8A(gene name)|psi-mi:ZBTB8A(display_short)|uniprotkb:BOZF1(gene name synonym)|uniprotkb:BTB/POZ and zinc-finger domain-containing factor(gene name synonym)|uniprotkb:BTB/POZ and zinc-finger domains factor on chromosome 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11545975|imex:IM-24995-2495	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013440.1|sgd:S000004328|mint:Q06132|dip:DIP-6333N|ensemblfungi:YLR336C(gene)|ensemblfungi:YLR336C_mRNA(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0006972"(hyperosmotic response)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0097078"(FAL1-SGD1 complex)|interpro:IPR003890(MIF4G-like, type 3)|interpro:IPR003891(Initiation factor eIF-4 gamma, MA3)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR016024(Armadillo-type fold)|sgd:YLR336C(identity)	ensembl:ENSG00000160062(gene)|ensembl:ENST00000373510(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|refseq:NP_001035531.2|refseq:NP_001278425.1|entrezgene/locuslink:653121(identity)	-	crc64:8EEFDB8258407FF3	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:FxZCxGejbcvEs/J2h1HEaWeVZLQ559292	rogid:tsrPT2tHvuBryODKgRXnceXz9s09606	intact-crc:5864B6F679580B29|rigid:OrBST+5s2tv+JURxyCkkkwDRIBs	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8NHQ1	uniprotkb:Q06132	intact:EBI-739624|ensembl:ENSP00000264982|ensembl:ENSP00000419231|uniprotkb:Q96B31|uniprotkb:Q9H2C3|uniprotkb:Q9H2Z1|uniprotkb:Q9H940|uniprotkb:D3DNE9|uniprotkb:B7Z5I8|uniprotkb:B7Z7E8|uniprotkb:F5GZX8	intact:EBI-34377|uniprotkb:D6VYX6|ensemblfungi:YLR336C	psi-mi:cep70_human(display_long)|uniprotkb:CEP70(gene name)|psi-mi:CEP70(display_short)|uniprotkb:BITE(gene name synonym)|uniprotkb:p10-binding protein(gene name synonym)	psi-mi:sgd1_yeast(display_long)|uniprotkb:SGD1(gene name)|psi-mi:SGD1(display_short)|uniprotkb:YLR336C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11545966|imex:IM-24995-2494	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114107(gene)|ensembl:ENST00000264982(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|interpro:IPR019734|interpro:IPR037692|mint:Q8NHQ1|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|ensembl:ENST00000484888(transcript)|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_077817.2|refseq:XP_016862764.1|refseq:NP_001275893.1|refseq:NP_001275894.1|refseq:NP_001275895.1|refseq:NP_001275896.1|refseq:NP_001307527.1|refseq:NP_001307529.1|entrezgene/locuslink:80321(identity)	refseq:NP_013440.1|sgd:S000004328|mint:Q06132|dip:DIP-6333N|ensemblfungi:YLR336C(gene)|ensemblfungi:YLR336C_mRNA(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0006972"(hyperosmotic response)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0097078"(FAL1-SGD1 complex)|interpro:IPR003890(MIF4G-like, type 3)|interpro:IPR003891(Initiation factor eIF-4 gamma, MA3)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR016024(Armadillo-type fold)|sgd:YLR336C(identity)	-	-	crc64:8EEFDB8258407FF3	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:S4yveQWcvdVtAUX65gqrJ5Dv0Mc9606	rogid:FxZCxGejbcvEs/J2h1HEaWeVZLQ559292	intact-crc:9FFE5E2FED44360E|rigid:PjjAmKyVVhJH+yc25AGY624IdxM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9HAN9	uniprotkb:Q06178	intact:EBI-3917542|uniprotkb:Q8TAE9|uniprotkb:Q9H6B6|uniprotkb:Q9H247|uniprotkb:B1AN63|ensembl:ENSP00000366410|ensembl:ENSP00000435134	intact:EBI-11803|ensemblfungi:YLR328W|uniprotkb:D6VYX0	psi-mi:nmna1_human(display_long)|uniprotkb:NMNAT1(gene name)|psi-mi:NMNAT1(display_short)|uniprotkb:NMNAT(gene name synonym)|uniprotkb:Nicotinate-nucleotide adenylyltransferase 1(gene name synonym)|uniprotkb:Nicotinamide-nucleotide adenylyltransferase 1(gene name synonym)	psi-mi:nma1_yeast(display_long)|uniprotkb:NMA1(gene name)|psi-mi:NMA1(display_short)|uniprotkb:"NAD(+) pyrophosphorylase 1"(gene name synonym)|uniprotkb:"NAD(+) diphosphorylase 1"(gene name synonym)|uniprotkb:Nicotinamide-nucleotide adenylyltransferase 1(gene name synonym)|uniprotkb:Nicotinate-nucleotide adenylyltransferase 1(gene name synonym)|uniprotkb:L8543.16(orf name)|uniprotkb:YLR328W(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11546022|imex:IM-24995-2500	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001284707.1|refseq:NP_073624.2|ensembl:ENSG00000173614(gene)|ensembl:ENST00000377205(transcript)|ensembl:ENST00000462686(transcript)|go:"GO:0000309"(nicotinamide-nucleotide adenylyltransferase activity)|go:"GO:0004515"(nicotinate-nucleotide adenylyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0009165"(nucleotide biosynthetic process)|go:"GO:0009435"(NAD biosynthetic process)|go:"GO:0009611"(response to wounding)|go:"GO:0016604"(nuclear body)|go:"GO:0042802"(identical protein binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:1902511"(negative regulation of apoptotic DNA fragmentation)|go:"GO:1990966"(ATP generation from poly-ADP-D-ribose)|interpro:IPR004821(Cytidyltransferase-related)|interpro:IPR005248(Probable nicotinate-nucleotide adenylyltransferase)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|mint:Q9HAN9|rcsb pdb:1GZU|rcsb pdb:1KKU|rcsb pdb:1KQN|rcsb pdb:1KQO|rcsb pdb:1KR2|reactome:R-HSA-196807|refseq:XP_016857596.1|dip:DIP-60881N|entrezgene/locuslink:64802(identity)	ensemblfungi:YLR328W(gene)|ensemblfungi:YLR328W_mRNA(transcript)|go:"GO:0000309"(nicotinamide-nucleotide adenylyltransferase activity)|go:"GO:0004515"(nicotinate-nucleotide adenylyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009435"(NAD biosynthetic process)|go:"GO:0042802"(identical protein binding)|interpro:IPR004821(Cytidyltransferase-related)|interpro:IPR005248(Probable nicotinate-nucleotide adenylyltransferase)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|reactome:R-SCE-196807|refseq:NP_013432.1|sgd:S000004320|dip:DIP-1228N|mint:Q06178|sgd:YLR328W(identity)	-	-	crc64:A176964E56A30DD8	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:KwV9lz04z3ptlVpKu3b534Yekpc9606	rogid:VzrKsykGbQsR8Eh7CHCwn/bCID8559292	intact-crc:5786688EC8E41244|rigid:7dZJEHyGoAiPQXKWTkcPwt6rJi0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q06178	uniprotkb:P63279	intact:EBI-11803|ensemblfungi:YLR328W|uniprotkb:D6VYX0	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	psi-mi:nma1_yeast(display_long)|uniprotkb:NMA1(gene name)|psi-mi:NMA1(display_short)|uniprotkb:"NAD(+) pyrophosphorylase 1"(gene name synonym)|uniprotkb:"NAD(+) diphosphorylase 1"(gene name synonym)|uniprotkb:Nicotinamide-nucleotide adenylyltransferase 1(gene name synonym)|uniprotkb:Nicotinate-nucleotide adenylyltransferase 1(gene name synonym)|uniprotkb:L8543.16(orf name)|uniprotkb:YLR328W(locus name)	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11546013|imex:IM-24995-2499	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YLR328W(gene)|ensemblfungi:YLR328W_mRNA(transcript)|go:"GO:0000309"(nicotinamide-nucleotide adenylyltransferase activity)|go:"GO:0004515"(nicotinate-nucleotide adenylyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009435"(NAD biosynthetic process)|go:"GO:0042802"(identical protein binding)|interpro:IPR004821(Cytidyltransferase-related)|interpro:IPR005248(Probable nicotinate-nucleotide adenylyltransferase)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|reactome:R-SCE-196807|refseq:NP_013432.1|sgd:S000004320|dip:DIP-1228N|mint:Q06178|sgd:YLR328W(identity)	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N|entrezgene/locuslink:7329(identity)	-	crc64:A176964E56A30DD8	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:VzrKsykGbQsR8Eh7CHCwn/bCID8559292	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	intact-crc:2F93DF72640ABF83|rigid:2h914wn3NQRlmLY0vGS3NzozEBE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8N6Y0	uniprotkb:Q06162	intact:EBI-739895|uniprotkb:Q8NBX7|uniprotkb:Q96KH3|uniprotkb:Q9BYI8|uniprotkb:A8K7L6|uniprotkb:B2RCR9|ensembl:ENSP00000252597	intact:EBI-34256|uniprotkb:D6VYV9|ensemblfungi:YLR315W	psi-mi:usbp1_human(display_long)|uniprotkb:USHBP1(gene name)|psi-mi:USHBP1(display_short)|uniprotkb:MCC-2(gene name synonym)|uniprotkb:AIE-75-binding protein(gene name synonym)|uniprotkb:AIEBP(gene name synonym)|uniprotkb:MCC2(gene name synonym)|uniprotkb:Mutated in colon cancer protein 2(gene name synonym)	psi-mi:nkp2_yeast(display_long)|uniprotkb:NKP2(gene name)|psi-mi:NKP2(display_short)|uniprotkb:Non-essential kinetochore protein 2(gene name synonym)|uniprotkb:YLR315W(locus name)|uniprotkb:Constitutive centromere-associated network protein NKP2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11546004|imex:IM-24995-2498	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001284632.1|refseq:NP_114147.2|refseq:NP_001308346.1|ensembl:ENSG00000130307(gene)|ensembl:ENST00000252597(transcript)|go:"GO:0030165"(PDZ domain binding)|interpro:IPR019536|interpro:IPR040171|entrezgene/locuslink:83878(identity)	sgd:S000004307|refseq:NP_013419.1|mint:Q06162|dip:DIP-1939N|ensemblfungi:YLR315W(gene)|ensemblfungi:YLR315W_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0007059"(chromosome segregation)|go:"GO:0031511"(Mis6-Sim4 complex)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|interpro:IPR018565|rcsb pdb:6NUW|rcsb pdb:6QLD|rcsb pdb:6QLE|rcsb pdb:6QLF|sgd:YLR315W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:vY1qx73Ju/z7WDu6k1kd10ZDVRo9606	rogid:MT2+IEz8xQ2SVU5vvYYBI91cVKo559292	intact-crc:1D7FCBD78175E283|rigid:Rq472ti3Fh+ZBVW5tCcxmNtu0/I	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96BA8	uniprotkb:Q06144	intact:EBI-6942903|ensembl:ENSP00000481956|intact:MINT-268046|intact:MINT-8162577|uniprotkb:Q8N2D5|uniprotkb:Q96CP0	intact:EBI-34916|uniprotkb:D6VYY8|ensemblfungi:YLR350W	psi-mi:cr3l1_human(display_long)|uniprotkb:CREB3L1(gene name)|psi-mi:CREB3L1(display_short)|uniprotkb:OASIS(gene name synonym)|uniprotkb:PSEC0238(orf name)|uniprotkb:Old astrocyte specifically-induced substance(gene name synonym)	psi-mi:orm2_yeast(display_long)|uniprotkb:ORM2(gene name)|psi-mi:ORM2(display_short)|uniprotkb:YLR350W(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11545995|imex:IM-24995-2497	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157613(gene)|ensembl:ENST00000621158(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0070278"(extracellular matrix constituent secretion)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029805|mint:Q96BA8|reactome:R-HSA-8874211|refseq:NP_443086.1|entrezgene/locuslink:90993(identity)	refseq:NP_013454.1|sgd:S000004342|mint:Q06144|dip:DIP-5579N|ensemblfungi:YLR350W(gene)|ensemblfungi:YLR350W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035339"(SPOTS complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0090155"(negative regulation of sphingolipid biosynthetic process)|go:"GO:0090156"(cellular sphingolipid homeostasis)|go:"GO:1900060"(negative regulation of ceramide biosynthetic process)|interpro:IPR007203(ORMDL)|reactome:R-SCE-6798695|sgd:YLR350W(identity)	-	comment:mint|function:"Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE"	crc64:2F474503CAB7C195	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:sMWUFmBeBBCO+T0Y2CuB/un1lBg9606	rogid:sY9Jt1Ogpw+lL+9cnBqUeXBiBdE559292	intact-crc:7D0F8AC260E41229|rigid:6cdPaXf69FAZGGC+M/4eauab+6w	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O15209	uniprotkb:Q06287	intact:EBI-723574|uniprotkb:Q5HYV4|uniprotkb:Q5STL0|uniprotkb:Q5STR7|uniprotkb:Q8WV82|ensembl:ENSP00000372683|ensembl:ENSP00000388191|ensembl:ENSP00000393514|ensembl:ENSP00000396292|ensembl:ENSP00000404403|ensembl:ENSP00000407545|uniprotkb:B0V007	intact:EBI-11979|ensemblfungi:YLR186W|uniprotkb:E9P8U2|uniprotkb:D6VYI9	psi-mi:zbt22_human(display_long)|uniprotkb:Zinc finger protein 297(gene name synonym)|uniprotkb:Protein BING1(gene name synonym)|uniprotkb:Zinc finger and BTB domain-containing protein 22A(gene name synonym)|uniprotkb:ZBTB22(gene name)|psi-mi:ZBTB22(display_short)|uniprotkb:BING1(gene name synonym)|uniprotkb:ZBTB22A(gene name synonym)|uniprotkb:ZNF297(gene name synonym)	psi-mi:nep1_yeast(display_long)|uniprotkb:EMG1(gene name)|psi-mi:EMG1(display_short)|uniprotkb:NEP1(gene name synonym)|uniprotkb:YLR186W(locus name)|uniprotkb:L9470.5(orf name)|uniprotkb:Nucleolar essential protein 1(gene name synonym)|uniprotkb:"18S rRNA (pseudouridine(1189)-N1)-methyltransferase"(gene name synonym)|uniprotkb:Essential for mitotic growth protein 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11546049|imex:IM-24995-2503	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001138810.1|refseq:NP_005444.4|ensembl:ENSG00000206280(gene)|ensembl:ENSG00000227780(gene)|ensembl:ENSG00000229253(gene)|ensembl:ENSG00000236104(gene)|ensembl:ENSG00000237056(gene)|ensembl:ENST00000418724(transcript)|ensembl:ENST00000431845(transcript)|ensembl:ENST00000445320(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR029833|interpro:IPR036236|ensembl:ENST00000383196(transcript)|ensembl:ENST00000416097(transcript)|ensembl:ENST00000418540(transcript)|dip:DIP-62047N|entrezgene/locuslink:9278(identity)	go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005880"(nuclear microtubule)|go:"GO:0006364"(rRNA processing)|go:"GO:0019843"(rRNA binding)|go:"GO:0030686"(90S preribosome)|go:"GO:0031167"(rRNA methylation)|go:"GO:0032040"(small-subunit processome)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0070037"("rRNA (pseudouridine) methyltransferase activity")|go:"GO:0070475"(rRNA base methylation)|interpro:IPR005304(Suppressor Mra1)|ensemblfungi:YLR186W(gene)|interpro:IPR029026|interpro:IPR029028|rcsb pdb:2V3J|rcsb pdb:2V3K|ensemblfungi:YLR186W_mRNA(transcript)|go:"GO:0000447"("endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000472"("endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000480"("endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0005634"(nucleus)|rcsb pdb:3OIJ|rcsb pdb:3OIN|rcsb pdb:5JPQ|rcsb pdb:5TZS|rcsb pdb:5WLC|rcsb pdb:5WYJ|rcsb pdb:5WYK|rcsb pdb:6KE6|rcsb pdb:6LQP|rcsb pdb:6LQQ|rcsb pdb:6LQR|rcsb pdb:6LQS|rcsb pdb:6LQT|rcsb pdb:6LQU|rcsb pdb:3OII|rcsb pdb:6LQV|rcsb pdb:6ZQA|rcsb pdb:6ZQB|rcsb pdb:6ZQC|rcsb pdb:6ZQD|rcsb pdb:6ZQE|rcsb pdb:6ZQF|rcsb pdb:6ZQG|rcsb pdb:7AJT|rcsb pdb:7AJU|sgd:S000004176|refseq:NP_013287.1|reactome:R-SCE-6791226|dip:DIP-6504N|sgd:YLR186W(identity)	-	-	crc64:4A8FCDA812051AD1	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:/u3Is9uJ0nS5Ru7xZKg4MqF6dzE9606	rogid:z62Fg9aJ4kKGgU5NIlAND2yHGrQ559292	intact-crc:8E044026380F3E0A|rigid:UMN0yqxmM5sRZxe9fSOd2ELtnJY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38159	uniprotkb:Q06251	intact:EBI-743526|ensembl:ENSP00000359645|uniprotkb:Q5JQ67|uniprotkb:Q969R3|uniprotkb:D3DWH0|uniprotkb:E9PG86|uniprotkb:Q8N8Y7|uniprotkb:B4E3U4	intact:EBI-32907|uniprotkb:D6VYI1|ensemblfungi:YLR177W	psi-mi:rbmx_human(display_long)|uniprotkb:Glycoprotein p43(gene name synonym)|uniprotkb:RBMX(gene name)|psi-mi:RBMX(display_short)|uniprotkb:HNRPG(gene name synonym)|uniprotkb:RBMXP1(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein G(gene name synonym)	psi-mi:yl177_yeast(display_long)|uniprotkb:YLR177W(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11546031|imex:IM-24995-2501	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000147274(gene)|ensembl:ENST00000320676(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000791"(euchromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0044530"(supraspliceosomal complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0006509"(membrane protein ectodomain proteolysis)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012604(RBM1CTR)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|mint:P38159|rcsb pdb:2MB0|rcsb pdb:2MKS|reactome:R-HSA-72163|reactome:R-HSA-72203|reactome:R-HSA-9013418|reactome:R-HSA-9013422|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273|refseq:NP_002130.2|refseq:NP_001158275.1|dip:DIP-34447N|entrezgene/locuslink:27316(identity)	refseq:NP_013278.1|sgd:S000004167|mint:Q06251|dip:DIP-4804N|ensemblfungi:YLR177W(gene)|ensemblfungi:YLR177W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|interpro:IPR007557(PSP1 C-terminal conserved region)|sgd:YLR177W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:ocCkdy9PxjeVLUQf0tMVCEhFfO89606	rogid:24pYGcKZbt39dfb9ITA+NxFPo0Y559292	intact-crc:697F5EF0DF1ACBAD|rigid:rSwQZlrHqP4qnxoHvnar+f6S5+I	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P62258	uniprotkb:Q06251	intact:EBI-356498|uniprotkb:P29360|uniprotkb:P42655|uniprotkb:Q53XZ5|uniprotkb:Q63631|uniprotkb:Q7M4R4|uniprotkb:B3KY71|uniprotkb:D3DTH5|uniprotkb:Q4VJB6|ensembl:ENSP00000264335|ensembl:ENSP00000487356	intact:EBI-32907|uniprotkb:D6VYI1|ensemblfungi:YLR177W	psi-mi:1433e_human(display_long)|uniprotkb:YWHAE(gene name)|psi-mi:YWHAE(display_short)	psi-mi:yl177_yeast(display_long)|uniprotkb:YLR177W(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11546040|imex:IM-24995-2502	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006752.1|dip:DIP-36676N|reactome:R-HSA-1445148|reactome:R-HSA-2028269|reactome:R-HSA-205025|reactome:R-HSA-2565942|reactome:R-HSA-3371453|reactome:R-HSA-3371511|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-75035|reactome:R-HSA-8854518|reactome:R-HSA-8862803|reactome:R-HSA-8876198|ensembl:ENSG00000108953(gene)|ensembl:ENSG00000274474(gene)|ensembl:ENST00000264335(transcript)|ensembl:ENST00000627231(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0003064"(regulation of heart rate by hormone)|go:"GO:0003723"(RNA binding)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005925"(focal adhesion)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050815"(phosphoserine residue binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099072"(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:"GO:1901016"(regulation of potassium ion transmembrane transporter activity)|go:"GO:1901020"(negative regulation of calcium ion transmembrane transporter activity)|go:"GO:1902309"(negative regulation of peptidyl-serine dephosphorylation)|go:"GO:1905913"(negative regulation of calcium ion export across plasma membrane)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P62258|rcsb pdb:2BR9|rcsb pdb:3UAL|rcsb pdb:3UBW|rcsb pdb:6EIH|rcsb pdb:7C8E|reactome:R-HSA-111447|entrezgene/locuslink:7531(identity)	refseq:NP_013278.1|sgd:S000004167|mint:Q06251|dip:DIP-4804N|ensemblfungi:YLR177W(gene)|ensemblfungi:YLR177W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|interpro:IPR007557(PSP1 C-terminal conserved region)|sgd:YLR177W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:mnuAjdnQZbMFojll2PnV3xFklXQ9606	rogid:24pYGcKZbt39dfb9ITA+NxFPo0Y559292	intact-crc:A286AC2A024B48B4|rigid:i2S8lHUrARRRAcIR3XbOtl9ht4o	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q06340	uniprotkb:P63279	intact:EBI-33799|uniprotkb:D6VSZ1|ensemblfungi:YDR363W	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	psi-mi:esc2_yeast(display_long)|uniprotkb:YDR363W(locus name)|uniprotkb:ESC2(gene name)|psi-mi:ESC2(display_short)|uniprotkb:Establishes silent chromatin protein 2(gene name synonym)	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11546062|imex:IM-24995-2504	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010650.1|sgd:S000002771|dip:DIP-5219N|ensemblfungi:YDR363W(gene)|ensemblfungi:YDR363W_mRNA(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0033235"(positive regulation of protein sumoylation)|interpro:IPR000626(Ubiquitin)|interpro:IPR022617|interpro:IPR029071|sgd:YDR363W(identity)	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N|entrezgene/locuslink:7329(identity)	-	crc64:F691FB73ED2FAF15	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:LgEXHq17g/of0LB8TeMRHcceivk559292	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	intact-crc:B9B50BC4C4A8F579|rigid:RE7bWgGGogHJBLPghe37QCyAJF4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q06411	uniprotkb:Q05D60	intact:EBI-576|uniprotkb:D6VZ60|ensemblfungi:YLR424W	intact:EBI-748597|uniprotkb:Q8NEF1|uniprotkb:Q96LL7|intact:EBI-10177066|uniprotkb:E9PJR5|ensembl:ENSP00000298050	psi-mi:sp382_yeast(display_long)|uniprotkb:NTR1(gene name synonym)|uniprotkb:YLR424W(locus name)|uniprotkb:SPP382(gene name)|psi-mi:SPP382(display_short)|uniprotkb:CCF8(gene name synonym)|uniprotkb:Suppressor of PRP38 protein 2(gene name synonym)|uniprotkb:Nineteen complex-related protein 1(gene name synonym)|uniprotkb:CLF1 complex factor 8(gene name synonym)	psi-mi:deup1_human(display_long)|uniprotkb:CCDC67(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 67(gene name synonym)|uniprotkb:DEUP1(gene name)|psi-mi:DEUP1(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11546109|imex:IM-24995-2509	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013528.1|sgd:S000004416|dip:DIP-1491N|mint:Q06411|ensemblfungi:YLR424W(gene)|ensemblfungi:YLR424W_mRNA(transcript)|go:"GO:0000349"(generation of catalytic spliceosome for first transesterification step)|go:"GO:0000390"(spliceosomal complex disassembly)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0071008"(U2-type post-mRNA release spliceosomal complex)|go:"GO:1904876"(negative regulation of DNA ligase activity)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR000467(D111/G-patch)|rcsb pdb:5Y88|sgd:YLR424W(identity)	refseq:NP_857596.2|refseq:XP_005273859.1|ensembl:ENSG00000165325(gene)|ensembl:ENST00000298050(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005814"(centriole)|go:"GO:0007099"(centriole replication)|go:"GO:0042802"(identical protein binding)|go:"GO:0098535"(de novo centriole assembly involved in multi-ciliated epithelial cell differentiation)|go:"GO:0098536"(deuterosome)|go:"GO:1903251"(multi-ciliated epithelial cell differentiation)|interpro:IPR029611|interpro:IPR031470|go:"GO:0030030"(cell projection organization)|entrezgene/locuslink:159989(identity)	-	crc64:9986B547B9582338	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:HrG54vTE2zs7jxPSzi+9eeA23/k559292	rogid:/d2HVFtI68hr7u7nqJdBUwn06bE9606	intact-crc:7EB7CB065018D3CA|rigid:8PqKGM3lyIAAkFS+iM5UgSYr6zg	false	-	sufficient binding region:265-604	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P01011	uniprotkb:Q06389	intact:EBI-296557|uniprotkb:Q9UC47|uniprotkb:Q13703|uniprotkb:Q2TU87|uniprotkb:Q2TU88|uniprotkb:Q59GP9|uniprotkb:Q6LBY8|uniprotkb:Q6LDT7|uniprotkb:Q6NSC9|uniprotkb:Q8N177|uniprotkb:Q96DW8|uniprotkb:Q9UNU9|uniprotkb:B3KVQ7|ensembl:ENSP00000376793|ensembl:ENSP00000376795|ensembl:ENSP00000450540	intact:EBI-11946|ensemblfungi:YDR373W|uniprotkb:D6VT04	psi-mi:aact_human(display_long)|uniprotkb:Cell growth-inhibiting gene 24/25 protein(gene name synonym)|uniprotkb:SERPINA3(gene name)|psi-mi:SERPINA3(display_short)|uniprotkb:AACT(gene name synonym)|uniprotkb:GIG24(orf name)|uniprotkb:GIG25(orf name)|uniprotkb:Serpin A3(gene name synonym)	psi-mi:ncs1_yeast(display_long)|uniprotkb:FRQ1(gene name)|psi-mi:FRQ1(display_short)|uniprotkb:NCS1(gene name synonym)|uniprotkb:YDR373W(locus name)|uniprotkb:D9481.6(orf name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11546071|imex:IM-24995-2505	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0006953"(acute-phase response)|refseq:NP_001076.2|ensembl:ENSG00000196136(gene)|ensembl:ENST00000393078(transcript)|ensembl:ENST00000393080(transcript)|ensembl:ENST00000467132(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|reactome:R-HSA-6798695|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0030277"(maintenance of gastrointestinal epithelium)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|interpro:IPR000215(Protease inhibitor I4, serpin)|go:"GO:0006954"(inflammatory response)|interpro:IPR023795|interpro:IPR023796|go:"GO:0010951"(negative regulation of endopeptidase activity)|interpro:IPR036186|interpro:IPR042178|interpro:IPR042185|mint:P01011|rcsb pdb:1AS4|rcsb pdb:1QMN|rcsb pdb:2ACH|rcsb pdb:3CAA|rcsb pdb:3DLW|rcsb pdb:4CAA|rcsb pdb:6HGE|reactome:R-HSA-114608|entrezgene/locuslink:12(identity)	ensemblfungi:YDR373W(gene)|ensemblfungi:YDR373W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0033101"(cellular bud membrane)|go:"GO:0043128"(positive regulation of 1-phosphatidylinositol 4-kinase activity)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR028846|rcsb pdb:1FPW|rcsb pdb:2JU0|reactome:R-SCE-2514859|refseq:NP_010661.3|sgd:S000002781|mint:Q06389|dip:DIP-2733N|sgd:YDR373W(identity)	-	-	crc64:5E9D7F48F8AADA21	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:LTdrRsWwtOm8QvOWZ4h0SO8EuP09606	rogid:8mxxTP8CHNx24fQcjCxgDE7xhbs559292	intact-crc:E4C5334C71B7BDCC|rigid:n9tp04GjADA1tlOpNF09vF0RG90	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q53EZ4	uniprotkb:Q06411	intact:EBI-747776|uniprotkb:Q32WF5|uniprotkb:Q3MV20|uniprotkb:Q5VY28|uniprotkb:Q6N034|ensembl:ENSP00000360540|uniprotkb:Q96H32|uniprotkb:Q9NVS7|uniprotkb:B2RDG8|intact:EBI-10173536|uniprotkb:D3DR37|intact:EBI-28973801	intact:EBI-576|uniprotkb:D6VZ60|ensemblfungi:YLR424W	psi-mi:cep55_human(display_long)|uniprotkb:Up-regulated in colon cancer 6(gene name synonym)|uniprotkb:CEP55(gene name)|psi-mi:CEP55(display_short)|uniprotkb:URCC6(gene name synonym)|uniprotkb:C10orf3(gene name synonym)	psi-mi:sp382_yeast(display_long)|uniprotkb:NTR1(gene name synonym)|uniprotkb:YLR424W(locus name)|uniprotkb:SPP382(gene name)|psi-mi:SPP382(display_short)|uniprotkb:CCF8(gene name synonym)|uniprotkb:Suppressor of PRP38 protein 2(gene name synonym)|uniprotkb:Nineteen complex-related protein 1(gene name synonym)|uniprotkb:CLF1 complex factor 8(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11546120|imex:IM-24995-2510	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001120654.1|refseq:NP_060601.3|ensembl:ENSG00000138180(gene)|ensembl:ENST00000371485(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0014066"(regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0030496"(midbody)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042802"(identical protein binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0061952"(midbody abscission)|go:"GO:0090543"(Flemming body)|go:"GO:1904888"(cranial skeletal system development)|interpro:IPR022008|interpro:IPR038926|mint:Q53EZ4|rcsb pdb:3E1R|rcsb pdb:3WUT|rcsb pdb:3WUU|rcsb pdb:3WUV|go:"GO:0005814"(centriole)|ensembl:ENSP00000360540|dip:DIP-44581N|entrezgene/locuslink:55165(identity)	refseq:NP_013528.1|sgd:S000004416|dip:DIP-1491N|mint:Q06411|ensemblfungi:YLR424W(gene)|ensemblfungi:YLR424W_mRNA(transcript)|go:"GO:0000349"(generation of catalytic spliceosome for first transesterification step)|go:"GO:0000390"(spliceosomal complex disassembly)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0071008"(U2-type post-mRNA release spliceosomal complex)|go:"GO:1904876"(negative regulation of DNA ligase activity)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR000467(D111/G-patch)|rcsb pdb:5Y88|sgd:YLR424W(identity)	-	-	crc64:9986B547B9582338	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:tuo36vVb8ZgPDR81YjZFNEg559w9606	rogid:HrG54vTE2zs7jxPSzi+9eeA23/k559292	intact-crc:64D9F4874316E754|rigid:h0XN/2wUCVo5EFf2F1nVYCyhxCE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8NHQ1	uniprotkb:Q06411	intact:EBI-739624|ensembl:ENSP00000264982|ensembl:ENSP00000419231|uniprotkb:Q96B31|uniprotkb:Q9H2C3|uniprotkb:Q9H2Z1|uniprotkb:Q9H940|uniprotkb:D3DNE9|uniprotkb:B7Z5I8|uniprotkb:B7Z7E8|uniprotkb:F5GZX8	intact:EBI-576|uniprotkb:D6VZ60|ensemblfungi:YLR424W	psi-mi:cep70_human(display_long)|uniprotkb:CEP70(gene name)|psi-mi:CEP70(display_short)|uniprotkb:BITE(gene name synonym)|uniprotkb:p10-binding protein(gene name synonym)	psi-mi:sp382_yeast(display_long)|uniprotkb:NTR1(gene name synonym)|uniprotkb:YLR424W(locus name)|uniprotkb:SPP382(gene name)|psi-mi:SPP382(display_short)|uniprotkb:CCF8(gene name synonym)|uniprotkb:Suppressor of PRP38 protein 2(gene name synonym)|uniprotkb:Nineteen complex-related protein 1(gene name synonym)|uniprotkb:CLF1 complex factor 8(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11546129|imex:IM-24995-2511	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114107(gene)|ensembl:ENST00000264982(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|interpro:IPR019734|interpro:IPR037692|mint:Q8NHQ1|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|ensembl:ENST00000484888(transcript)|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_077817.2|refseq:XP_016862764.1|refseq:NP_001275893.1|refseq:NP_001275894.1|refseq:NP_001275895.1|refseq:NP_001275896.1|refseq:NP_001307527.1|refseq:NP_001307529.1|entrezgene/locuslink:80321(identity)	refseq:NP_013528.1|sgd:S000004416|dip:DIP-1491N|mint:Q06411|ensemblfungi:YLR424W(gene)|ensemblfungi:YLR424W_mRNA(transcript)|go:"GO:0000349"(generation of catalytic spliceosome for first transesterification step)|go:"GO:0000390"(spliceosomal complex disassembly)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0071008"(U2-type post-mRNA release spliceosomal complex)|go:"GO:1904876"(negative regulation of DNA ligase activity)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR000467(D111/G-patch)|rcsb pdb:5Y88|sgd:YLR424W(identity)	-	-	crc64:9986B547B9582338	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:S4yveQWcvdVtAUX65gqrJ5Dv0Mc9606	rogid:HrG54vTE2zs7jxPSzi+9eeA23/k559292	intact-crc:2981A05F8513A795|rigid:8gVaAftn5+nVBMvX2UnEShT6XlE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38432	uniprotkb:Q06411	intact:EBI-945751|uniprotkb:B2R931|ensembl:ENSP00000240316	intact:EBI-576|uniprotkb:D6VZ60|ensemblfungi:YLR424W	psi-mi:coil_human(display_long)|uniprotkb:COIL(gene name)|psi-mi:COIL(display_short)|uniprotkb:CLN80(gene name synonym)|uniprotkb:p80-coilin(gene name synonym)	psi-mi:sp382_yeast(display_long)|uniprotkb:NTR1(gene name synonym)|uniprotkb:YLR424W(locus name)|uniprotkb:SPP382(gene name)|psi-mi:SPP382(display_short)|uniprotkb:CCF8(gene name synonym)|uniprotkb:Suppressor of PRP38 protein 2(gene name synonym)|uniprotkb:Nineteen complex-related protein 1(gene name synonym)|uniprotkb:CLF1 complex factor 8(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11546100|imex:IM-24995-2508	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004636.1|dip:DIP-38503N|ensembl:ENSG00000121058(gene)|ensembl:ENST00000240316(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0015030"(Cajal body)|go:"GO:0016020"(membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0030619"(U1 snRNA binding)|go:"GO:0030620"(U2 snRNA binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR024822|interpro:IPR031722|mint:P38432|entrezgene/locuslink:8161(identity)	refseq:NP_013528.1|sgd:S000004416|dip:DIP-1491N|mint:Q06411|ensemblfungi:YLR424W(gene)|ensemblfungi:YLR424W_mRNA(transcript)|go:"GO:0000349"(generation of catalytic spliceosome for first transesterification step)|go:"GO:0000390"(spliceosomal complex disassembly)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0071008"(U2-type post-mRNA release spliceosomal complex)|go:"GO:1904876"(negative regulation of DNA ligase activity)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR000467(D111/G-patch)|rcsb pdb:5Y88|sgd:YLR424W(identity)	-	-	crc64:9986B547B9582338	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:hd5p6AbyA/GYNEeca99Mdb41qM09606	rogid:HrG54vTE2zs7jxPSzi+9eeA23/k559292	intact-crc:044EB9144674691E|rigid:kt448FdSg/2TjseZenFZiXDSbyE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O75071	uniprotkb:Q06408	intact:EBI-2805635|ensembl:ENSP00000361001|uniprotkb:Q5SXB8|uniprotkb:D3DQ23	intact:EBI-32807|uniprotkb:D6VT13|ensemblfungi:YDR380W	psi-mi:efc14_human(display_long)|uniprotkb:EFCAB14(gene name)|psi-mi:EFCAB14(display_short)|uniprotkb:KIAA0494(gene name synonym)	psi-mi:aro10_yeast(display_long)|uniprotkb:ARO10(gene name)|psi-mi:ARO10(display_short)|uniprotkb:YDR380W(locus name)|uniprotkb:D9481.3(orf name)|uniprotkb:Transaminated branched-chain amino acid decarboxylase(gene name synonym)|uniprotkb:Thiamine diphosphate-dependent phenylpyruvate decarboxylase(gene name synonym)|uniprotkb:Thiamine pyrophosphate-dependent 2-oxo-acid decarboxylase(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11546091|imex:IM-24995-2507	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000159658(gene)|ensembl:ENST00000371933(transcript)|go:"GO:0005509"(calcium ion binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR042352|refseq:NP_055589.1|entrezgene/locuslink:9813(identity)	sgd:S000002788|refseq:NP_010668.3|dip:DIP-5252N|mint:Q06408|ensemblfungi:YDR380W(gene)|ensemblfungi:YDR380W_mRNA(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000949"(aromatic amino acid family catabolic process to alcohol via Ehrlich pathway)|go:"GO:0000950"(branched-chain amino acid catabolic process to alcohol via Ehrlich pathway)|go:"GO:0000951"(methionine catabolic process to 3-methylthiopropanol)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006552"(leucine catabolic process)|go:"GO:0006559"(L-phenylalanine catabolic process)|go:"GO:0006569"(tryptophan catabolic process)|go:"GO:0006572"(tyrosine catabolic process)|go:"GO:0016831"(carboxy-lyase activity)|go:"GO:0030976"(thiamine pyrophosphate binding)|go:"GO:0047433"(branched-chain-2-oxoacid decarboxylase activity)|go:"GO:0047434"(indolepyruvate decarboxylase activity)|go:"GO:0050177"(phenylpyruvate decarboxylase activity)|go:"GO:0050546"(4-hydroxyphenylpyruvate decarboxylase activity)|interpro:IPR011766(Thiamine pyrophosphate enzyme, C-terminal TPP-binding)|interpro:IPR012000(Thiamine pyrophosphate enzyme, central region)|interpro:IPR012001(Thiamine pyrophosphate enzyme, N-terminal TPP binding region)|interpro:IPR012110(Pyruvate decarboxylase/indolepyruvate decarboxylase)|interpro:IPR029035|interpro:IPR029061|sgd:YDR380W(identity)	-	-	crc64:616DF7E06DA82415	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:UhD1cgnq+/XOmI2Y7LZ7ANpf9wA9606	rogid:jh443SvRXK8vb+GUjPq95NB8jdU559292	intact-crc:B904B64150BD1736|rigid:6mjUoJ6yUoAOiX3za3cyKoGN3Nw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q86UW9	uniprotkb:Q06389	intact:EBI-740376|uniprotkb:Q96H69|uniprotkb:Q9H890|uniprotkb:Q9P200|uniprotkb:Q6XM88|ensembl:ENSP00000322885|ensembl:ENSP00000390218|ensembl:ENSP00000411986|uniprotkb:Q6XM87|intact:EBI-10192429|uniprotkb:Q4ZH49	intact:EBI-11946|ensemblfungi:YDR373W|uniprotkb:D6VT04	psi-mi:dtx2_human(display_long)|uniprotkb:RING finger protein 58(gene name synonym)|uniprotkb:DTX2(gene name)|psi-mi:DTX2(display_short)|uniprotkb:KIAA1528(gene name synonym)|uniprotkb:RNF58(gene name synonym)|uniprotkb:Protein deltex-2(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase DTX2(gene name synonym)	psi-mi:ncs1_yeast(display_long)|uniprotkb:FRQ1(gene name)|psi-mi:FRQ1(display_short)|uniprotkb:NCS1(gene name synonym)|uniprotkb:YDR373W(locus name)|uniprotkb:D9481.6(orf name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11546081|imex:IM-24995-2506	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001096064.1|refseq:NP_001096065.1|refseq:NP_001096066.1|refseq:NP_065943.2|ensembl:ENSP00000322885|ensembl:ENSP00000390218|ensembl:ENSP00000411986|ensembl:ENST00000446820|ensembl:ENSP00000392545|ensembl:ENSG00000091073(gene)|ensembl:ENST00000324432(transcript)|ensembl:ENST00000413936(transcript)|ensembl:ENST00000430490(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031965"(nuclear membrane)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR004170(WWE)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR018123|interpro:IPR018957|interpro:IPR037197|interpro:IPR039396|interpro:IPR039398|interpro:IPR039399|mint:Q86UW9|rcsb pdb:6IR0|rcsb pdb:6Y22|rcsb pdb:6Y2X|rcsb pdb:6Y3J|reactome:R-HSA-2122948|refseq:XP_011514074.1|refseq:XP_011514075.1|refseq:XP_011514076.1|refseq:XP_011514077.1|refseq:XP_005250188.1|refseq:XP_005250189.1|refseq:XP_016867212.1|refseq:XP_016867213.1|refseq:XP_016867214.1|refseq:XP_016867215.1|refseq:XP_016867216.1|entrezgene/locuslink:113878(identity)	ensemblfungi:YDR373W(gene)|ensemblfungi:YDR373W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0033101"(cellular bud membrane)|go:"GO:0043128"(positive regulation of 1-phosphatidylinositol 4-kinase activity)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR028846|rcsb pdb:1FPW|rcsb pdb:2JU0|reactome:R-SCE-2514859|refseq:NP_010661.3|sgd:S000002781|mint:Q06389|dip:DIP-2733N|sgd:YDR373W(identity)	-	-	crc64:5E9D7F48F8AADA21	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:ugnjqAbG6Ekyc8MGugCnjc9zVaI9606	rogid:8mxxTP8CHNx24fQcjCxgDE7xhbs559292	intact-crc:41BF271A028B968A|rigid:3wWYrx4hFjPIVMUN/p7zZOP9Wqg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8N5R6	uniprotkb:Q06543	intact:EBI-740841|intact:EBI-953781|uniprotkb:B3KQ49|uniprotkb:A8K3U4|uniprotkb:A8MPQ6|uniprotkb:A8MV61|uniprotkb:A8MVU9|uniprotkb:Q9H5Q6|uniprotkb:Q8TAX6|intact:EBI-2320546|intact:EBI-11522976	intact:EBI-33132|uniprotkb:D6VYP1|ensemblfungi:YLR243W	psi-mi:ccd33_human(display_long)|uniprotkb:CCDC33(gene name)|psi-mi:CCDC33(display_short)|uniprotkb:Cancer/testis antigen 61(gene name synonym)	psi-mi:gpn3_yeast(display_long)|uniprotkb:GPN3(gene name)|psi-mi:GPN3(display_short)|uniprotkb:YLR243W(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11546176|imex:IM-24995-2516	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_079331.3|interpro:IPR000008(C2 calcium-dependent membrane targeting)|go:"GO:0005777"(peroxisome)|refseq:NP_001274110.1|refseq:NP_877592.2|mint:Q8N5R6|interpro:IPR035892|interpro:IPR039889|entrezgene/locuslink:80125(identity)	refseq:NP_013344.1|sgd:S000004233|dip:DIP-1911N|ensemblfungi:YLR243W(gene)|ensemblfungi:YLR243W_mRNA(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007064"(mitotic sister chromatid cohesion)|interpro:IPR004130(Protein of unknown function, ATP binding)|interpro:IPR027417|interpro:IPR030228|sgd:YLR243W(identity)	-	-	crc64:96E478B8DD5988BB	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2021/11/30	rogid:eEIn7pQyfdHWx8TeLJpYy0i/gww9606	rogid:XGJg0/XoYEbfio5kpjB/7Q9Cvjc559292	intact-crc:1DC51A66B40254D0|rigid:M7pDBzuMW3ZgO/PQHF9jUqOW4og	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UKT9	uniprotkb:Q06411	intact:EBI-747204|uniprotkb:Q8WWQ9|uniprotkb:Q8WWR0|uniprotkb:Q8WWR1|uniprotkb:Q8WWR2|uniprotkb:Q8WWR3|uniprotkb:Q8N574|uniprotkb:B4DVV5|uniprotkb:Q69BL6|uniprotkb:Q69BL7|uniprotkb:Q69BL8|uniprotkb:Q69BL9|uniprotkb:Q69BM0|uniprotkb:Q69BM1|uniprotkb:Q69BM2|uniprotkb:Q69BM3|uniprotkb:Q69BM5|ensembl:ENSP00000344544	intact:EBI-576|uniprotkb:D6VZ60|ensemblfungi:YLR424W	psi-mi:ikzf3_human(display_long)|uniprotkb:ZNFN1A3(gene name synonym)|uniprotkb:Ikaros family zinc finger protein 3(gene name synonym)|uniprotkb:IKZF3(gene name)|psi-mi:IKZF3(display_short)	psi-mi:sp382_yeast(display_long)|uniprotkb:NTR1(gene name synonym)|uniprotkb:YLR424W(locus name)|uniprotkb:SPP382(gene name)|psi-mi:SPP382(display_short)|uniprotkb:CCF8(gene name synonym)|uniprotkb:Suppressor of PRP38 protein 2(gene name synonym)|uniprotkb:Nineteen complex-related protein 1(gene name synonym)|uniprotkb:CLF1 complex factor 8(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11546167|imex:IM-24995-2515	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001271443.1|refseq:NP_001271444.1|refseq:NP_036613.2|refseq:NP_899051.1|refseq:NP_899052.1|refseq:NP_899053.1|refseq:NP_899054.1|refseq:NP_899055.1|refseq:NP_001271445.1|refseq:NP_001244337.1|refseq:NP_001244338.1|refseq:NP_001244339.1|refseq:NP_001244340.1|refseq:NP_001244341.1|refseq:NP_001244342.1|refseq:NP_001244343.1|ensembl:ENSG00000161405(gene)|ensembl:ENST00000346872(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007498"(mesoderm development)|go:"GO:0009617"(response to bacterium)|go:"GO:0030888"(regulation of B cell proliferation)|go:"GO:0042113"(B cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045577"(regulation of B cell differentiation)|go:"GO:0045619"(regulation of lymphocyte differentiation)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|go:"GO:0046872"(metal ion binding)|dip:DIP-56975N|entrezgene/locuslink:22806(identity)	refseq:NP_013528.1|sgd:S000004416|dip:DIP-1491N|mint:Q06411|ensemblfungi:YLR424W(gene)|ensemblfungi:YLR424W_mRNA(transcript)|go:"GO:0000349"(generation of catalytic spliceosome for first transesterification step)|go:"GO:0000390"(spliceosomal complex disassembly)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0071008"(U2-type post-mRNA release spliceosomal complex)|go:"GO:1904876"(negative regulation of DNA ligase activity)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR000467(D111/G-patch)|rcsb pdb:5Y88|sgd:YLR424W(identity)	-	-	crc64:9986B547B9582338	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:2Kp6LefSLfK5VIiE6DmQusFIfMY9606	rogid:HrG54vTE2zs7jxPSzi+9eeA23/k559292	intact-crc:827E188B71ABD483|rigid:7PHYXTkfUcGLLjnZ7vE+v4asd6U	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UJV3-2	uniprotkb:Q06411	intact:EBI-10172526|ensembl:ENSP00000413976	intact:EBI-576|uniprotkb:D6VZ60|ensemblfungi:YLR424W	psi-mi:q9ujv3-2(display_long)|uniprotkb:RING-type E3 ubiquitin transferase MID2(gene name synonym)|uniprotkb:FXY2(gene name synonym)|uniprotkb:Midin-2(gene name synonym)|uniprotkb:Midline defect 2(gene name synonym)|uniprotkb:Midline-2(gene name synonym)|uniprotkb:RING finger protein 60(gene name synonym)|uniprotkb:RNF60(gene name synonym)|uniprotkb:TRIM1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 1(gene name synonym)|uniprotkb:MID2(gene name)|psi-mi:MID2(display_short)	psi-mi:sp382_yeast(display_long)|uniprotkb:NTR1(gene name synonym)|uniprotkb:YLR424W(locus name)|uniprotkb:SPP382(gene name)|psi-mi:SPP382(display_short)|uniprotkb:CCF8(gene name synonym)|uniprotkb:Suppressor of PRP38 protein 2(gene name synonym)|uniprotkb:Nineteen complex-related protein 1(gene name synonym)|uniprotkb:CLF1 complex factor 8(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11546156|imex:IM-24995-2514	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-751983(isoform-parent)|uniprotkb:Q9UJV3-2(isoform-parent)|ensembl:ENSG00000080561(gene)|ensembl:ENST00000443968(transcript)|entrezgene/locuslink:11043(identity)	refseq:NP_013528.1|sgd:S000004416|dip:DIP-1491N|mint:Q06411|ensemblfungi:YLR424W(gene)|ensemblfungi:YLR424W_mRNA(transcript)|go:"GO:0000349"(generation of catalytic spliceosome for first transesterification step)|go:"GO:0000390"(spliceosomal complex disassembly)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0071008"(U2-type post-mRNA release spliceosomal complex)|go:"GO:1904876"(negative regulation of DNA ligase activity)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR000467(D111/G-patch)|rcsb pdb:5Y88|sgd:YLR424W(identity)	-	-	crc64:9986B547B9582338	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:/FJ+V2H7SaWon7caUWkEkmHFVxQ9606	rogid:HrG54vTE2zs7jxPSzi+9eeA23/k559292	intact-crc:F4A0E7D493681366|rigid:aCrhFYu1TtUd69F8tpEKOaWJIBc	false	sufficient binding region:21-705	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q06411	uniprotkb:Q9NS73-5	intact:EBI-576|uniprotkb:D6VZ60|ensemblfungi:YLR424W	intact:EBI-10182361|ensembl:ENSP00000324444	psi-mi:sp382_yeast(display_long)|uniprotkb:NTR1(gene name synonym)|uniprotkb:YLR424W(locus name)|uniprotkb:SPP382(gene name)|psi-mi:SPP382(display_short)|uniprotkb:CCF8(gene name synonym)|uniprotkb:Suppressor of PRP38 protein 2(gene name synonym)|uniprotkb:Nineteen complex-related protein 1(gene name synonym)|uniprotkb:CLF1 complex factor 8(gene name synonym)	psi-mi:q9ns73-5(display_long)|uniprotkb:MAPK upstream kinase-binding inhibitory protein(gene name synonym)|uniprotkb:BM-015(orf name)|uniprotkb:MBIP(gene name)|psi-mi:MBIP(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11546147|imex:IM-24995-2513	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013528.1|sgd:S000004416|dip:DIP-1491N|mint:Q06411|ensemblfungi:YLR424W(gene)|ensemblfungi:YLR424W_mRNA(transcript)|go:"GO:0000349"(generation of catalytic spliceosome for first transesterification step)|go:"GO:0000390"(spliceosomal complex disassembly)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0071008"(U2-type post-mRNA release spliceosomal complex)|go:"GO:1904876"(negative regulation of DNA ligase activity)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR000467(D111/G-patch)|rcsb pdb:5Y88|sgd:YLR424W(identity)	ensembl:ENSG00000151332(gene)|ensembl:ENST00000318473(transcript)|intact:EBI-741953(isoform-parent)|uniprotkb:Q9NS73-5(isoform-parent)|entrezgene/locuslink:51562(identity)	-	crc64:9986B547B9582338	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:HrG54vTE2zs7jxPSzi+9eeA23/k559292	rogid:JVmcJrT3SXRZwv9U285cNqnXWQE9606	intact-crc:93E4F56A52AE2C32|rigid:jFJGl0qhOY6Tud0wyHcxNT3P9XU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q06543	uniprotkb:Q8N0S2	intact:EBI-33132|uniprotkb:D6VYP1|ensemblfungi:YLR243W	intact:EBI-6872807|ensembl:ENSP00000341282|uniprotkb:Q9BWU4|uniprotkb:B2RC80|uniprotkb:Q9BWU3	psi-mi:gpn3_yeast(display_long)|uniprotkb:GPN3(gene name)|psi-mi:GPN3(display_short)|uniprotkb:YLR243W(locus name)	psi-mi:syce1_human(display_long)|uniprotkb:C10orf94(gene name synonym)|uniprotkb:Cancer/testis antigen 76(gene name synonym)|uniprotkb:SYCE1(gene name)|psi-mi:SYCE1(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11546185|imex:IM-24995-2517	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013344.1|sgd:S000004233|dip:DIP-1911N|ensemblfungi:YLR243W(gene)|ensemblfungi:YLR243W_mRNA(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007064"(mitotic sister chromatid cohesion)|interpro:IPR004130(Protein of unknown function, ATP binding)|interpro:IPR027417|interpro:IPR030228|sgd:YLR243W(identity)	ensembl:ENSG00000171772(gene)|ensembl:ENST00000343131(transcript)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0000801"(central element)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051301"(cell division)|interpro:IPR026676|reactome:R-HSA-1221632|refseq:NP_001137235.1|refseq:NP_570140.1|entrezgene/locuslink:93426(identity)	-	crc64:96E478B8DD5988BB	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:XGJg0/XoYEbfio5kpjB/7Q9Cvjc559292	rogid:qLVqIlFiwZJHFfoyYXV3jrqdd609606	intact-crc:7F26EF39B92D5237|rigid:nA5S7YO2+jToqKP3IVfrj1+eboU	false	-	sufficient binding region:37-351	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9NS73	uniprotkb:Q06411	intact:EBI-741953|uniprotkb:Q86TZ2|uniprotkb:Q96AS5|uniprotkb:Q9BS93|uniprotkb:Q9NZE1|ensembl:ENSP00000399718	intact:EBI-576|uniprotkb:D6VZ60|ensemblfungi:YLR424W	psi-mi:mbip1_human(display_long)|uniprotkb:MAPK upstream kinase-binding inhibitory protein(gene name synonym)|uniprotkb:MBIP(gene name)|psi-mi:MBIP(display_short)|uniprotkb:BM-015(orf name)	psi-mi:sp382_yeast(display_long)|uniprotkb:NTR1(gene name synonym)|uniprotkb:YLR424W(locus name)|uniprotkb:SPP382(gene name)|psi-mi:SPP382(display_short)|uniprotkb:CCF8(gene name synonym)|uniprotkb:Suppressor of PRP38 protein 2(gene name synonym)|uniprotkb:Nineteen complex-related protein 1(gene name synonym)|uniprotkb:CLF1 complex factor 8(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11546138|imex:IM-24995-2512	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001138363.1|refseq:NP_057670.2|ensembl:ENSG00000151332(gene)|ensembl:ENST00000416007(transcript)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0042802"(identical protein binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0046330"(positive regulation of JNK cascade)|interpro:IPR026062|mint:Q9NS73|reactome:R-HSA-3214847|go:"GO:0005654"(nucleoplasm)|refseq:NP_001295039.1|entrezgene/locuslink:51562(identity)	refseq:NP_013528.1|sgd:S000004416|dip:DIP-1491N|mint:Q06411|ensemblfungi:YLR424W(gene)|ensemblfungi:YLR424W_mRNA(transcript)|go:"GO:0000349"(generation of catalytic spliceosome for first transesterification step)|go:"GO:0000390"(spliceosomal complex disassembly)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0071008"(U2-type post-mRNA release spliceosomal complex)|go:"GO:1904876"(negative regulation of DNA ligase activity)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR000467(D111/G-patch)|rcsb pdb:5Y88|sgd:YLR424W(identity)	-	-	crc64:9986B547B9582338	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:PjaEuab6wwOyGImpNYFZfQ+TUvU9606	rogid:HrG54vTE2zs7jxPSzi+9eeA23/k559292	intact-crc:B06F98BB8FE68618|rigid:8UFlC1frtUrvlYzYlmHIuHNhawM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q06630	uniprotkb:O95273	intact:EBI-36794|uniprotkb:D6VSS5|ensemblfungi:YDR296W	intact:EBI-748961|uniprotkb:A8K3Q0|uniprotkb:A8K3U2|uniprotkb:Q6ZQN9|uniprotkb:Q7Z519|uniprotkb:Q8NBS7|uniprotkb:Q8NBY2|uniprotkb:Q9NS19|uniprotkb:Q9NYH3|uniprotkb:Q9UHX9|ensembl:ENSP00000300213	psi-mi:mhr1_yeast(display_long)|uniprotkb:MHR1(gene name)|psi-mi:MHR1(display_short)|uniprotkb:YDR296W(locus name)|uniprotkb:Cross-linked transcription component 1(gene name synonym)|uniprotkb:XTC1(gene name synonym)|uniprotkb:Mitochondrial large ribosomal subunit protein mL67(gene name synonym)	psi-mi:ccdb1_human(display_long)|uniprotkb:Grap2 and cyclin-D-interacting protein(gene name synonym)|uniprotkb:Human homolog of Maid(gene name synonym)|uniprotkb:CCNDBP1(gene name)|psi-mi:CCNDBP1(display_short)|uniprotkb:DIP1(gene name synonym)|uniprotkb:GCIP(gene name synonym)|uniprotkb:HHM(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11546265|imex:IM-24995-2525	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002704|refseq:NP_010582.3|mint:Q06630|dip:DIP-5727N|ensemblfungi:YDR296W(gene)|ensemblfungi:YDR296W_mRNA(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0000150"(DNA strand exchange activity)|go:"GO:0003677"(DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0006310"(DNA recombination)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0032543"(mitochondrial translation)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0090297"(positive regulation of mitochondrial DNA replication)|interpro:IPR024629|rcsb pdb:3J6B|rcsb pdb:5MRC|rcsb pdb:5MRE|rcsb pdb:5MRF|sgd:YDR296W(identity)	refseq:NP_036274.3|ensembl:ENSG00000166946(gene)|ensembl:ENST00000300213(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0016604"(nuclear body)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR026907|mint:O95273|rcsb pdb:3AY5|entrezgene/locuslink:23582(identity)	-	crc64:F26903A4814091C4	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:eA38S7UNOpP716XSQ0zzhYm2TqA559292	rogid:Vi9aoFc+Mov6P3X6KGmsTxXqxvM9606	intact-crc:A6B2E5B92FC032BC|rigid:LtjyODNWPNiD5flamYEvq88v7kM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q06630	uniprotkb:O43586	intact:EBI-36794|uniprotkb:D6VSS5|ensemblfungi:YDR296W	intact:EBI-1050964|uniprotkb:O43585|uniprotkb:O95657|uniprotkb:B5BUK4|uniprotkb:B5BU74|ensembl:ENSP00000452746	psi-mi:mhr1_yeast(display_long)|uniprotkb:MHR1(gene name)|psi-mi:MHR1(display_short)|uniprotkb:YDR296W(locus name)|uniprotkb:Cross-linked transcription component 1(gene name synonym)|uniprotkb:XTC1(gene name synonym)|uniprotkb:Mitochondrial large ribosomal subunit protein mL67(gene name synonym)	psi-mi:ppip1_human(display_long)|uniprotkb:CD2-binding protein 1(gene name synonym)|uniprotkb:H-PIP(gene name synonym)|uniprotkb:PSTPIP1(gene name)|psi-mi:PSTPIP1(display_short)|uniprotkb:CD2BP1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11546256|imex:IM-24995-2524	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002704|refseq:NP_010582.3|mint:Q06630|dip:DIP-5727N|ensemblfungi:YDR296W(gene)|ensemblfungi:YDR296W_mRNA(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0000150"(DNA strand exchange activity)|go:"GO:0003677"(DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0006310"(DNA recombination)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0032543"(mitochondrial translation)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0090297"(positive regulation of mitochondrial DNA replication)|interpro:IPR024629|rcsb pdb:3J6B|rcsb pdb:5MRC|rcsb pdb:5MRE|rcsb pdb:5MRF|sgd:YDR296W(identity)	refseq:NP_003969.2|refseq:NP_001308064.1|refseq:NP_001308066.1|ensembl:ENSG00000140368(gene)|ensembl:ENST00000558012(transcript)|go:"GO:0001931"(uropod)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0006954"(inflammatory response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0032154"(cleavage furrow)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051015"(actin filament binding)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR027267|interpro:IPR030777|interpro:IPR031160|interpro:IPR036028|mint:O43586|rcsb pdb:2DIL|reactome:R-HSA-844456|reactome:R-HSA-9660826|entrezgene/locuslink:9051(identity)	-	crc64:F26903A4814091C4	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:eA38S7UNOpP716XSQ0zzhYm2TqA559292	rogid:JWK4dCYdcVF6mKwe+hoOri1wwps9606	intact-crc:A60AFEF491363767|rigid:AWoM5SLQmf4iBA6nWh7+UiNOxcU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O15156-2	uniprotkb:Q06630	intact:EBI-11522250|ensembl:ENSP00000406286	intact:EBI-36794|uniprotkb:D6VSS5|ensemblfungi:YDR296W	psi-mi:o15156-2(display_long)|uniprotkb:ZBTB7B(gene name)|psi-mi:ZBTB7B(display_short)|uniprotkb:Krueppel-related zinc finger protein cKrox(gene name synonym)|uniprotkb:T-helper-inducing POZ/Krueppel-like factor(gene name synonym)|uniprotkb:ZBTB15(gene name synonym)|uniprotkb:ZFP67(gene name synonym)|uniprotkb:ZNF857B(gene name synonym)|uniprotkb:Zinc finger and BTB domain-containing protein 15(gene name synonym)|uniprotkb:Zinc finger protein 67 homolog(gene name synonym)|uniprotkb:Zinc finger protein 857B(gene name synonym)|uniprotkb:Zinc finger protein Th-POK(gene name synonym)	psi-mi:mhr1_yeast(display_long)|uniprotkb:MHR1(gene name)|psi-mi:MHR1(display_short)|uniprotkb:YDR296W(locus name)|uniprotkb:Cross-linked transcription component 1(gene name synonym)|uniprotkb:XTC1(gene name synonym)|uniprotkb:Mitochondrial large ribosomal subunit protein mL67(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11546245|imex:IM-24995-2523	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-740434(isoform-parent)|ensembl:ENSG00000160685(gene)|ensembl:ENST00000417934(transcript)|uniprotkb:O15156-2(isoform-parent)|entrezgene/locuslink:51043(identity)	sgd:S000002704|refseq:NP_010582.3|mint:Q06630|dip:DIP-5727N|ensemblfungi:YDR296W(gene)|ensemblfungi:YDR296W_mRNA(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0000150"(DNA strand exchange activity)|go:"GO:0003677"(DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0006310"(DNA recombination)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0032543"(mitochondrial translation)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0090297"(positive regulation of mitochondrial DNA replication)|interpro:IPR024629|rcsb pdb:3J6B|rcsb pdb:5MRC|rcsb pdb:5MRE|rcsb pdb:5MRF|sgd:YDR296W(identity)	-	isoform-comment:No experimental confirmation available.	crc64:F26903A4814091C4	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:41NEFYyprTXI+fOHVFh78TPKF289606	rogid:eA38S7UNOpP716XSQ0zzhYm2TqA559292	intact-crc:30D2809C35942804|rigid:+gIfruCDlLpKi5ABf+MA+5VAKWI	false	sufficient binding region:35-573	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O14641	uniprotkb:Q06630	intact:EBI-740850|ensembl:ENSP00000005340|uniprotkb:Q53XM0|uniprotkb:D3DTN3	intact:EBI-36794|uniprotkb:D6VSS5|ensemblfungi:YDR296W	psi-mi:dvl2_human(display_long)|uniprotkb:DSH homolog 2(gene name synonym)|uniprotkb:DVL2(gene name)|psi-mi:DVL2(display_short)	psi-mi:mhr1_yeast(display_long)|uniprotkb:MHR1(gene name)|psi-mi:MHR1(display_short)|uniprotkb:YDR296W(locus name)|uniprotkb:Cross-linked transcription component 1(gene name synonym)|uniprotkb:XTC1(gene name synonym)|uniprotkb:Mitochondrial large ribosomal subunit protein mL67(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11546236|imex:IM-24995-2522	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004413.1|ensembl:ENSG00000004975(gene)|ensembl:ENST00000005340(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005109"(frizzled binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0007507"(heart development)|go:"GO:0016235"(aggresome)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044340"(canonical Wnt signaling pathway involved in regulation of cell proliferation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0150012"(positive regulation of neuron projection arborization)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008341(Dishevelled-2 region)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:O14641|rcsb pdb:2REY|rcsb pdb:3CBX|rcsb pdb:3CBY|rcsb pdb:3CBZ|rcsb pdb:3CC0|rcsb pdb:4WIP|rcsb pdb:5LNP|rcsb pdb:5SUY|rcsb pdb:5SUZ|rcsb pdb:6IW3|rcsb pdb:6JCK|reactome:R-HSA-201681|reactome:R-HSA-201688|reactome:R-HSA-2028269|reactome:R-HSA-4086400|reactome:R-HSA-4608870|reactome:R-HSA-4641258|reactome:R-HSA-4641262|reactome:R-HSA-5099900|reactome:R-HSA-5368598|reactome:R-HSA-5663220|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9673324|ensembl:ENSP00000005340|dip:DIP-34433N|entrezgene/locuslink:1856(identity)	sgd:S000002704|refseq:NP_010582.3|mint:Q06630|dip:DIP-5727N|ensemblfungi:YDR296W(gene)|ensemblfungi:YDR296W_mRNA(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0000150"(DNA strand exchange activity)|go:"GO:0003677"(DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0006310"(DNA recombination)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0032543"(mitochondrial translation)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0090297"(positive regulation of mitochondrial DNA replication)|interpro:IPR024629|rcsb pdb:3J6B|rcsb pdb:5MRC|rcsb pdb:5MRE|rcsb pdb:5MRF|sgd:YDR296W(identity)	-	-	crc64:F26903A4814091C4	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:2Vdc8oRnT4Mz/j+EXQXrL3AszOc9606	rogid:eA38S7UNOpP716XSQ0zzhYm2TqA559292	intact-crc:2077CB678EDA8A6E|rigid:KfACV2u1KAa7GX/3udfMqHYgtRY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q08379	uniprotkb:Q06630	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	intact:EBI-36794|uniprotkb:D6VSS5|ensemblfungi:YDR296W	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:mhr1_yeast(display_long)|uniprotkb:MHR1(gene name)|psi-mi:MHR1(display_short)|uniprotkb:YDR296W(locus name)|uniprotkb:Cross-linked transcription component 1(gene name synonym)|uniprotkb:XTC1(gene name synonym)|uniprotkb:Mitochondrial large ribosomal subunit protein mL67(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11546225|imex:IM-24995-2521	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N|entrezgene/locuslink:2801(identity)	sgd:S000002704|refseq:NP_010582.3|mint:Q06630|dip:DIP-5727N|ensemblfungi:YDR296W(gene)|ensemblfungi:YDR296W_mRNA(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0000150"(DNA strand exchange activity)|go:"GO:0003677"(DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0006310"(DNA recombination)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0032543"(mitochondrial translation)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0090297"(positive regulation of mitochondrial DNA replication)|interpro:IPR024629|rcsb pdb:3J6B|rcsb pdb:5MRC|rcsb pdb:5MRE|rcsb pdb:5MRF|sgd:YDR296W(identity)	-	-	crc64:F26903A4814091C4	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2017/05/26	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	rogid:eA38S7UNOpP716XSQ0zzhYm2TqA559292	intact-crc:65BDE37295218CB3|rigid:gl2QUcrSam/JZf9Zt3jttWwEaDQ	false	sufficient binding region:383-1002	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q06616	uniprotkb:Q8N6L0	intact:EBI-36065|uniprotkb:D6W4H5|ensemblfungi:YPR174C	intact:EBI-749265|uniprotkb:Q96MC3|ensembl:ENSP00000404220	psi-mi:yp174_yeast(display_long)|uniprotkb:YPR174C(locus name)	psi-mi:kash5_human(display_long)|uniprotkb:KASH5(gene name)|psi-mi:KASH5(display_short)|uniprotkb:CCDC155(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 155(gene name synonym)|uniprotkb:KASH domain-containing protein 5(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11546207|imex:IM-24995-2519	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015500.1|sgd:S000006378|dip:DIP-3800N|ensemblfungi:YPR174C(gene)|ensemblfungi:YPR174C_mRNA(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034399"(nuclear periphery)|interpro:IPR013743(Nap binding NBP1, fungi)|sgd:YPR174C(identity)	refseq:NP_653289.3|ensembl:ENSG00000161609(gene)|ensembl:ENST00000447857(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034397"(telomere localization)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051225"(spindle assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0090172"(microtubule cytoskeleton organization involved in homologous chromosome segregation)|go:"GO:0090220"(chromosome localization to nuclear envelope involved in homologous chromosome segregation)|go:"GO:0090619"(meiotic spindle pole)|interpro:IPR011992(EF-Hand type)|interpro:IPR028168|interpro:IPR028170|interpro:IPR039508|mint:Q8N6L0|rcsb pdb:6R2I|rcsb pdb:6WMF|entrezgene/locuslink:147872(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:R+7auDlEsOm+VR9gJ1jZsF3ST88559292	rogid:Wl9L7AcvDHCZuKjYLn8QgGIbZTc9606	intact-crc:02A4E62573C1AD63|rigid:HcU2H04ieLvzvIfH30kFyH3R7o0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q5SW96	uniprotkb:Q06616	intact:EBI-747813|uniprotkb:A2BHI5|uniprotkb:Q6TQS9|uniprotkb:Q8N2Y0|uniprotkb:Q9UFI9|intact:EBI-28971912|ensembl:ENSP00000363458	intact:EBI-36065|uniprotkb:D6W4H5|ensemblfungi:YPR174C	psi-mi:arh_human(display_long)|uniprotkb:Autosomal recessive hypercholesterolemia protein(gene name synonym)|uniprotkb:LDLRAP1(gene name)|psi-mi:LDLRAP1(display_short)|uniprotkb:ARH(gene name synonym)	psi-mi:yp174_yeast(display_long)|uniprotkb:YPR174C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11546196|imex:IM-24995-2518	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000363458|refseq:NP_056442.2|go:"GO:0042982"(amyloid precursor protein metabolic process)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0055037"(recycling endosome)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0090118"(receptor-mediated endocytosis involved in cholesterol transport)|go:"GO:0090205"(positive regulation of cholesterol metabolic process)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905581"(positive regulation of low-density lipoprotein particle clearance)|go:"GO:1905602"(positive regulation of receptor-mediated endocytosis involved in cholesterol transport)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|rcsb pdb:2G30|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8964026|reactome:R-HSA-8964038|ensembl:ENSG00000157978(gene)|ensembl:ENST00000374338(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005883"(neurofilament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030276"(clathrin binding)|go:"GO:0030301"(cholesterol transport)|go:"GO:0030424"(axon)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031623"(receptor internalization)|go:"GO:0034383"(low-density lipoprotein particle clearance)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0035612"(AP-2 adaptor complex binding)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0035650"(AP-1 adaptor complex binding)|go:"GO:0042632"(cholesterol homeostasis)|entrezgene/locuslink:26119(identity)	refseq:NP_015500.1|sgd:S000006378|dip:DIP-3800N|ensemblfungi:YPR174C(gene)|ensemblfungi:YPR174C_mRNA(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034399"(nuclear periphery)|interpro:IPR013743(Nap binding NBP1, fungi)|sgd:YPR174C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:dtBWLcVpVD/R0aKQZr9Nucfa1oo9606	rogid:R+7auDlEsOm+VR9gJ1jZsF3ST88559292	intact-crc:5289A7DDE34A4A55|rigid:PTA3oZL7c7aWBEoYMxjMcJObqJA	false	sufficient binding region:46-308	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q06616	uniprotkb:Q969F0	intact:EBI-36065|uniprotkb:D6W4H5|ensemblfungi:YPR174C	intact:EBI-743099|ensembl:ENSP00000359375	psi-mi:yp174_yeast(display_long)|uniprotkb:YPR174C(locus name)	psi-mi:fate1_human(display_long)|uniprotkb:Tumor antigen BJ-HCC-2(gene name synonym)|uniprotkb:Cancer/testis antigen 43(gene name synonym)|uniprotkb:FATE1(gene name)|psi-mi:FATE1(display_short)|uniprotkb:FATE(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11546216|imex:IM-24995-2520	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015500.1|sgd:S000006378|dip:DIP-3800N|ensemblfungi:YPR174C(gene)|ensemblfungi:YPR174C_mRNA(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034399"(nuclear periphery)|interpro:IPR013743(Nap binding NBP1, fungi)|sgd:YPR174C(identity)	refseq:NP_149076.1|ensembl:ENSG00000147378(gene)|ensembl:ENST00000370350(transcript)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|go:"GO:0051562"(negative regulation of mitochondrial calcium ion concentration)|interpro:IPR039153|interpro:IPR039433|mint:Q969F0|entrezgene/locuslink:89885(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:R+7auDlEsOm+VR9gJ1jZsF3ST88559292	rogid:Nm1N6lO92MHr5rIKC007oouF5RE9606	intact-crc:59295B88AE98183C|rigid:Lk+btTFjqrWeHn5nH/Yl1jEACt8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q06630	uniprotkb:Q13137	intact:EBI-36794|uniprotkb:D6VSS5|ensemblfungi:YDR296W	intact:EBI-739580|uniprotkb:B4DDC4|uniprotkb:E7ENK0|uniprotkb:Q53FQ5|uniprotkb:Q53HB5|uniprotkb:Q6IBN9|uniprotkb:Q9BTF7|uniprotkb:B2RBT0|ensembl:ENSP00000258947|uniprotkb:B4E0C0|uniprotkb:E7ETP5|uniprotkb:B4DDT4|uniprotkb:B4DP36|uniprotkb:E9PBE5	psi-mi:mhr1_yeast(display_long)|uniprotkb:MHR1(gene name)|psi-mi:MHR1(display_short)|uniprotkb:YDR296W(locus name)|uniprotkb:Cross-linked transcription component 1(gene name synonym)|uniprotkb:XTC1(gene name synonym)|uniprotkb:Mitochondrial large ribosomal subunit protein mL67(gene name synonym)	psi-mi:caco2_human(display_long)|uniprotkb:CALCOCO2(gene name)|psi-mi:CALCOCO2(display_short)|uniprotkb:NDP52(gene name synonym)|uniprotkb:Nuclear domain 10 protein NDP52(gene name synonym)|uniprotkb:Antigen nuclear dot 52 kDa protein(gene name synonym)|uniprotkb:Nuclear dot protein 52(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11546283|imex:IM-24995-2527	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002704|refseq:NP_010582.3|mint:Q06630|dip:DIP-5727N|ensemblfungi:YDR296W(gene)|ensemblfungi:YDR296W_mRNA(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0000150"(DNA strand exchange activity)|go:"GO:0003677"(DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0006310"(DNA recombination)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0032543"(mitochondrial translation)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0090297"(positive regulation of mitochondrial DNA replication)|interpro:IPR024629|rcsb pdb:3J6B|rcsb pdb:5MRC|rcsb pdb:5MRE|rcsb pdb:5MRF|sgd:YDR296W(identity)	refseq:NP_001248319.1|refseq:NP_001248320.1|refseq:NP_001248322.1|refseq:NP_005822.1|ensembl:ENSG00000136436(gene)|ensembl:ENST00000258947(transcript)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016032"(viral process)|go:"GO:0016605"(PML body)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0098792"(xenophagy)|go:"GO:1901098"(positive regulation of autophagosome maturation)|interpro:IPR041611|interpro:IPR041641|mint:Q13137|rcsb pdb:2MXP|rcsb pdb:3VVV|rcsb pdb:3VVW|rcsb pdb:4GXL|rcsb pdb:4HAN|rcsb pdb:4XKL|rcsb pdb:5AAQ|rcsb pdb:5Z7A|rcsb pdb:5Z7L|refseq:NP_001248324.1|dip:DIP-57534N|entrezgene/locuslink:10241(identity)	-	crc64:F26903A4814091C4	crc64:609B121DA1A9DCB8	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:eA38S7UNOpP716XSQ0zzhYm2TqA559292	rogid:N/GPJUGBK+Dh5Cg+csmafphuo9M9606	intact-crc:3C91EBC31E11C0E0|rigid:Y9bWtIjFM+q05QneRyN40QS46AA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q06630	uniprotkb:Q5JR59-3	intact:EBI-36794|uniprotkb:D6VSS5|ensemblfungi:YDR296W	intact:EBI-11522433|ensembl:ENSP00000370186	psi-mi:mhr1_yeast(display_long)|uniprotkb:MHR1(gene name)|psi-mi:MHR1(display_short)|uniprotkb:YDR296W(locus name)|uniprotkb:Cross-linked transcription component 1(gene name synonym)|uniprotkb:XTC1(gene name synonym)|uniprotkb:Mitochondrial large ribosomal subunit protein mL67(gene name synonym)	psi-mi:q5jr59-3(display_long)|uniprotkb:MTUS2(gene name)|psi-mi:MTUS2(display_short)|uniprotkb:CAZIP(gene name synonym)|uniprotkb:Cardiac zipper protein(gene name synonym)|uniprotkb:KIAA0774(gene name synonym)|uniprotkb:Microtubule plus-end tracking protein TIP150(gene name synonym)|uniprotkb:TIP150(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11546292|imex:IM-24995-2528	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002704|refseq:NP_010582.3|mint:Q06630|dip:DIP-5727N|ensemblfungi:YDR296W(gene)|ensemblfungi:YDR296W_mRNA(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0000150"(DNA strand exchange activity)|go:"GO:0003677"(DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0006310"(DNA recombination)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0032543"(mitochondrial translation)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0090297"(positive regulation of mitochondrial DNA replication)|interpro:IPR024629|rcsb pdb:3J6B|rcsb pdb:5MRC|rcsb pdb:5MRE|rcsb pdb:5MRF|sgd:YDR296W(identity)	ensembl:ENSG00000132938(gene)|ensembl:ENST00000380808(transcript)|intact:EBI-742948(isoform-parent)|uniprotkb:Q5JR59-3(isoform-parent)|entrezgene/locuslink:23281(identity)	-	crc64:F26903A4814091C4	isoform-comment:No experimental confirmation available.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:eA38S7UNOpP716XSQ0zzhYm2TqA559292	rogid:npId9tC7VoLN/jteoBiRbSYChPs9606	intact-crc:EDCE097890AF3422|rigid:FVW3iio5D5kaMySpXHM8SU1Py1A	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q06678	uniprotkb:Q8IYF3-3	intact:EBI-392|uniprotkb:D6VSV4|ensemblfungi:YDR322W	intact:EBI-11523345|ensembl:ENSP00000363453	psi-mi:rm35_yeast(display_long)|uniprotkb:MRPL35(gene name)|psi-mi:MRPL35(display_short)|uniprotkb:YDR322W(locus name)|uniprotkb:D9798.5(orf name)|uniprotkb:YmL35(gene name synonym)|uniprotkb:Mitochondrial large ribosomal subunit protein mL38(gene name synonym)	psi-mi:q8iyf3-3(display_long)|uniprotkb:TEX11(gene name)|psi-mi:TEX11(display_short)|uniprotkb:Protein ZIP4 homolog(gene name synonym)|uniprotkb:ZIP4(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11546348|imex:IM-24995-2534	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010608.1|sgd:S000002730|ensemblfungi:YDR322W(gene)|ensemblfungi:YDR322W_mRNA(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0030162"(regulation of proteolysis)|go:"GO:0030414"(peptidase inhibitor activity)|go:"GO:0046578"(regulation of Ras protein signal transduction)|interpro:IPR008914(Phosphatidylethanolamine-binding protein PEBP)|interpro:IPR035810|interpro:IPR036610|rcsb pdb:3J6B|rcsb pdb:5MRC|rcsb pdb:5MRE|rcsb pdb:5MRF|dip:DIP-6832N|mint:Q06678|sgd:YDR322W(identity)	ensembl:ENSG00000120498(gene)|ensembl:ENST00000374333(transcript)|intact:EBI-742397(isoform-parent)|uniprotkb:Q8IYF3-3(isoform-parent)|entrezgene/locuslink:56159(identity)	-	crc64:C6A2C973121FF555	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:yeCXJ6cEZO5bkf31Et3mVexib3A559292	rogid:PUAMFmnm5ZV2rnJ1rhm9ZeRCixg9606	intact-crc:84170B04FCBAB392|rigid:lazbbfxyaIRV1E+N0HRaOp/7iZU	false	-	sufficient binding region:9-925	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q15437	uniprotkb:Q06676	intact:EBI-742673|uniprotkb:Q5W183|uniprotkb:Q9BS15|uniprotkb:Q9BSI2|uniprotkb:Q9H1D7|intact:EBI-1048165|uniprotkb:Q503A9|uniprotkb:D3DW33|ensembl:ENSP00000262544|ensembl:ENSP00000338844|ensembl:ENSP00000366685|ensembl:ENSP00000497473	intact:EBI-30298|uniprotkb:D6VSV0|ensemblfungi:YDR319C	psi-mi:sc23b_human(display_long)|uniprotkb:SEC23-related protein B(gene name synonym)|uniprotkb:SEC23B(gene name)|psi-mi:SEC23B(display_short)	psi-mi:yft2_yeast(display_long)|uniprotkb:YFT2(gene name)|psi-mi:YFT2(display_short)|uniprotkb:FIT2A(gene name synonym)|uniprotkb:YDR319C(locus name)|uniprotkb:FIT family protein YFT2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11546339|imex:IM-24995-2533	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001166216.1|refseq:NP_006354.2|refseq:NP_116780.1|refseq:NP_116781.1|ensembl:ENSG00000101310(gene)|ensembl:ENST00000262544(transcript)|ensembl:ENST00000336714(transcript)|ensembl:ENST00000377465(transcript)|ensembl:ENST00000650089(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008270"(zinc ion binding)|go:"GO:0012505"(endomembrane system)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0090110"(COPII-coated vesicle cargo loading)|go:"GO:0070971"(endoplasmic reticulum exit site)|interpro:IPR006895(Zinc finger, Sec23/Sec24-type)|interpro:IPR006896(Sec23/Sec24 trunk region)|interpro:IPR006900(Sec23/Sec24 helical region)|interpro:IPR007123(Gelsolin region)|interpro:IPR012990(Sec23/Sec24 beta-sandwich)|interpro:IPR029006|interpro:IPR036174|interpro:IPR036175|interpro:IPR036180|interpro:IPR036465|interpro:IPR037364|interpro:IPR037550|mint:Q15437|refseq:XP_016883082.1|entrezgene/locuslink:10483(identity)	refseq:NP_010605.1|sgd:S000002727|dip:DIP-4731N|reactome:R-SCE-8964572|ensemblfungi:YDR319C(gene)|ensemblfungi:YDR319C_mRNA(transcript)|go:"GO:0005773"(vacuole)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0008654"(phospholipid biosynthetic process)|go:"GO:0016818"(hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides)|go:"GO:0019915"(lipid storage)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0034389"(lipid droplet organization)|go:"GO:0140042"(lipid droplet formation)|go:"GO:1900480"(regulation of diacylglycerol biosynthetic process)|go:"GO:1900481"(negative regulation of diacylglycerol biosynthetic process)|interpro:IPR019388|sgd:YDR319C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:+3KZ/1jjziSgJRcr81Axquofkl49606	rogid:gy1kXEPAQZisfcLxF3V95W1JR60559292	intact-crc:6B86E7CDE7EA09E7|rigid:aA65udexRxRSI7Ii6EO8Hq/9uCE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q06630	uniprotkb:O95751	intact:EBI-36794|uniprotkb:D6VSS5|ensemblfungi:YDR296W	intact:EBI-740738|ensembl:ENSP00000359557|uniprotkb:Q6IAR6	psi-mi:mhr1_yeast(display_long)|uniprotkb:MHR1(gene name)|psi-mi:MHR1(display_short)|uniprotkb:YDR296W(locus name)|uniprotkb:Cross-linked transcription component 1(gene name synonym)|uniprotkb:XTC1(gene name synonym)|uniprotkb:Mitochondrial large ribosomal subunit protein mL67(gene name synonym)	psi-mi:ldoc1_human(display_long)|uniprotkb:Leucine zipper protein down-regulated in cancer cells(gene name synonym)|uniprotkb:LDOC1(gene name)|psi-mi:LDOC1(display_short)|uniprotkb:BCUR1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11546274|imex:IM-24995-2526	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002704|refseq:NP_010582.3|mint:Q06630|dip:DIP-5727N|ensemblfungi:YDR296W(gene)|ensemblfungi:YDR296W_mRNA(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0000150"(DNA strand exchange activity)|go:"GO:0003677"(DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0006310"(DNA recombination)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0032543"(mitochondrial translation)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0090297"(positive regulation of mitochondrial DNA replication)|interpro:IPR024629|rcsb pdb:3J6B|rcsb pdb:5MRC|rcsb pdb:5MRE|rcsb pdb:5MRF|sgd:YDR296W(identity)	refseq:NP_036449.1|ensembl:ENSG00000182195(gene)|ensembl:ENST00000370526(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071225"(cellular response to muramyl dipeptide)|interpro:IPR032549|interpro:IPR032567|entrezgene/locuslink:23641(identity)	-	crc64:F26903A4814091C4	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:eA38S7UNOpP716XSQ0zzhYm2TqA559292	rogid:Ediu0oNiZ/+YVY8l3fNdgP5A+v09606	intact-crc:4CB55287F8F5E070|rigid:kvTpwC03DfjelXlTES8y8iAK6q0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q06667	uniprotkb:P51116	intact:EBI-33838|uniprotkb:D6VSU4|ensemblfungi:YDR315C	intact:EBI-740459|uniprotkb:Q8WUM2|uniprotkb:Q86V09|uniprotkb:B2R9M2|uniprotkb:D3DTQ1|ensembl:ENSP00000250113	psi-mi:ipk1_yeast(display_long)|uniprotkb:IPK1(gene name)|psi-mi:IPK1(display_short)|uniprotkb:GSL1(gene name synonym)|uniprotkb:Inositol-1,3,4,5,6-pentakisphosphate 2-kinase(gene name synonym)|uniprotkb:"Ins(1,3,4,5,6)P5 2-kinase"(gene name synonym)|uniprotkb:YDR315C(locus name)	psi-mi:fxr2_human(display_long)|uniprotkb:FXR2(gene name)|psi-mi:FXR2(display_short)|uniprotkb:FMR1L2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11546321|imex:IM-24995-2531	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002723|reactome:R-SCE-1855167|reactome:R-SCE-1855191|refseq:NP_010601.3|dip:DIP-1388N|ensemblfungi:YDR315C(gene)|ensemblfungi:YDR315C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0032958"(inositol phosphate biosynthetic process)|go:"GO:0035299"(inositol pentakisphosphate 2-kinase activity)|go:"GO:0052746"(inositol phosphorylation)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|interpro:IPR009286(Protein of unknown function DUF941)|sgd:YDR315C(identity)	interpro:IPR004087(K Homology)|refseq:NP_004851.2|ensembl:ENSG00000129245(gene)|ensembl:ENST00000250113(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0044326"(dendritic spine neck)|go:"GO:0045182"(translation regulator activity)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0098793"(presynapse)|go:"GO:1902737"(dendritic filopodium)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|interpro:IPR004088(K Homology, type 1)|interpro:IPR008395(Agenet)|interpro:IPR022034|interpro:IPR032172|interpro:IPR036612|interpro:IPR040148|interpro:IPR040472|interpro:IPR041560|mint:P51116|rcsb pdb:3H8Z|entrezgene/locuslink:9513(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Fd1kGHt2rvWznhiE9yFCTiLo2oY559292	rogid:NnYgyzD2NRGIO1ZHukr5qy44qRE9606	intact-crc:41F0269C1C87AC4F|rigid:8Gufg/KxGSlSinauyqQH63xULZc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UJV3-2	uniprotkb:Q06630	intact:EBI-10172526|ensembl:ENSP00000413976	intact:EBI-36794|uniprotkb:D6VSS5|ensemblfungi:YDR296W	psi-mi:q9ujv3-2(display_long)|uniprotkb:RING-type E3 ubiquitin transferase MID2(gene name synonym)|uniprotkb:FXY2(gene name synonym)|uniprotkb:Midin-2(gene name synonym)|uniprotkb:Midline defect 2(gene name synonym)|uniprotkb:Midline-2(gene name synonym)|uniprotkb:RING finger protein 60(gene name synonym)|uniprotkb:RNF60(gene name synonym)|uniprotkb:TRIM1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 1(gene name synonym)|uniprotkb:MID2(gene name)|psi-mi:MID2(display_short)	psi-mi:mhr1_yeast(display_long)|uniprotkb:MHR1(gene name)|psi-mi:MHR1(display_short)|uniprotkb:YDR296W(locus name)|uniprotkb:Cross-linked transcription component 1(gene name synonym)|uniprotkb:XTC1(gene name synonym)|uniprotkb:Mitochondrial large ribosomal subunit protein mL67(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11546310|imex:IM-24995-2530	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-751983(isoform-parent)|uniprotkb:Q9UJV3-2(isoform-parent)|ensembl:ENSG00000080561(gene)|ensembl:ENST00000443968(transcript)|entrezgene/locuslink:11043(identity)	sgd:S000002704|refseq:NP_010582.3|mint:Q06630|dip:DIP-5727N|ensemblfungi:YDR296W(gene)|ensemblfungi:YDR296W_mRNA(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0000150"(DNA strand exchange activity)|go:"GO:0003677"(DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0006310"(DNA recombination)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0032543"(mitochondrial translation)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0090297"(positive regulation of mitochondrial DNA replication)|interpro:IPR024629|rcsb pdb:3J6B|rcsb pdb:5MRC|rcsb pdb:5MRE|rcsb pdb:5MRF|sgd:YDR296W(identity)	-	-	crc64:F26903A4814091C4	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:/FJ+V2H7SaWon7caUWkEkmHFVxQ9606	rogid:eA38S7UNOpP716XSQ0zzhYm2TqA559292	intact-crc:EC8875F5B17957D2|rigid:uav9RSJq+r8k5yH7EhWpKx59nQ0	false	sufficient binding region:21-705	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q92997	uniprotkb:Q06630	intact:EBI-739789|uniprotkb:O14642|uniprotkb:Q13531|uniprotkb:Q8N5E9|uniprotkb:Q92607|uniprotkb:D3DNT0|intact:EBI-11081380|uniprotkb:B4E3E5|ensembl:ENSP00000316054	intact:EBI-36794|uniprotkb:D6VSS5|ensemblfungi:YDR296W	psi-mi:dvl3_human(display_long)|uniprotkb:DVL3(gene name)|psi-mi:DVL3(display_short)|uniprotkb:KIAA0208(gene name synonym)|uniprotkb:DSH homolog 3(gene name synonym)	psi-mi:mhr1_yeast(display_long)|uniprotkb:MHR1(gene name)|psi-mi:MHR1(display_short)|uniprotkb:YDR296W(locus name)|uniprotkb:Cross-linked transcription component 1(gene name synonym)|uniprotkb:XTC1(gene name synonym)|uniprotkb:Mitochondrial large ribosomal subunit protein mL67(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11546301|imex:IM-24995-2529	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004414.3|dip:DIP-34509N|ensembl:ENSG00000161202(gene)|ensembl:ENST00000313143(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002020"(protease binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005109"(frizzled binding)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0038031"(non-canonical Wnt signaling pathway via JNK cascade)|go:"GO:0042493"|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050821"(protein stabilization)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0150012"(positive regulation of neuron projection arborization)|go:"GO:1903827"|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008342(Dishevelled-3 protein, C-terminal)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:Q92997|rcsb pdb:6V7O|rcsb pdb:6ZC6|rcsb pdb:6ZC8|reactome:R-HSA-201681|reactome:R-HSA-201688|reactome:R-HSA-4086400|reactome:R-HSA-4641258|reactome:R-HSA-4641262|reactome:R-HSA-5368598|reactome:R-HSA-5663220|reactome:R-HSA-9673324|entrezgene/locuslink:1857(identity)	sgd:S000002704|refseq:NP_010582.3|mint:Q06630|dip:DIP-5727N|ensemblfungi:YDR296W(gene)|ensemblfungi:YDR296W_mRNA(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0000150"(DNA strand exchange activity)|go:"GO:0003677"(DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0006310"(DNA recombination)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0032543"(mitochondrial translation)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0090297"(positive regulation of mitochondrial DNA replication)|interpro:IPR024629|rcsb pdb:3J6B|rcsb pdb:5MRC|rcsb pdb:5MRE|rcsb pdb:5MRF|sgd:YDR296W(identity)	-	-	crc64:F26903A4814091C4	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:yJ3YIp5IhvKTQwa3bK5yTjNyqXk9606	rogid:eA38S7UNOpP716XSQ0zzhYm2TqA559292	intact-crc:5858E793ED62D7D6|rigid:VeX5lQL9qHsDTykQ7ACrwGxW3y0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q13422-7	uniprotkb:Q06671	intact:EBI-11522367|ensembl:ENSP00000352123|ensembl:ENSP00000413025	intact:EBI-3685534|uniprotkb:D6VZ66|ensemblfungi:YLR431C	psi-mi:q13422-7(display_long)|uniprotkb:IKZF1(gene name)|psi-mi:IKZF1(display_short)|uniprotkb:IK1(gene name synonym)|uniprotkb:IKAROS(gene name synonym)|uniprotkb:Ikaros family zinc finger protein 1(gene name synonym)|uniprotkb:LYF1(gene name synonym)|uniprotkb:Lymphoid transcription factor LyF-1(gene name synonym)|uniprotkb:ZNFN1A1(gene name synonym)	psi-mi:atg23_yeast(display_long)|uniprotkb:ATG23(gene name)|psi-mi:ATG23(display_short)|uniprotkb:CVT23(gene name synonym)|uniprotkb:Cytoplasm to vacuole targeting protein 23(gene name synonym)|uniprotkb:YLR431C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11546330|imex:IM-24995-2532	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-745305(isoform-parent)|ensembl:ENSG00000185811(gene)|ensembl:ENST00000359197(transcript)|ensembl:ENST00000439701(transcript)|uniprotkb:Q13422-7(isoform-parent)|entrezgene/locuslink:10320(identity)	sgd:S000004423|refseq:NP_013535.1|ensemblfungi:YLR431C(gene)|ensemblfungi:YLR431C_mRNA(transcript)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0044805"(late nucleophagy)|sgd:YLR431C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:ou/ovXYoMneBNVp4pj38VxenfyY9606	rogid:6KEtQbyIfmG3hnxsqr3+hHGrEa0559292	intact-crc:E4E9A572128F2C14|rigid:g+xJ5gDXbhYnOsvVB5FAHzXHfAk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q06707	uniprotkb:P19012	intact:EBI-32671|uniprotkb:D6VZ20|ensemblfungi:YLR385C	intact:EBI-739566|uniprotkb:Q53XV8|uniprotkb:Q9BUG4|uniprotkb:B3KQY1|uniprotkb:B3KRA2|uniprotkb:E0CX14|ensembl:ENSP00000254043|ensembl:ENSP00000377546	psi-mi:swc7_yeast(display_long)|uniprotkb:SWC7(gene name)|psi-mi:SWC7(display_short)|uniprotkb:AWS1(gene name synonym)|uniprotkb:YLR385C(locus name)	psi-mi:k1c15_human(display_long)|uniprotkb:KRT15(gene name)|psi-mi:KRT15(display_short)|uniprotkb:KRTB(gene name synonym)|uniprotkb:Cytokeratin-15(gene name synonym)|uniprotkb:Keratin-15(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11546359|imex:IM-24995-2535	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013489.1|sgd:S000004377|dip:DIP-4645N|mint:Q06707|ensemblfungi:YLR385C(gene)|ensemblfungi:YLR385C_mRNA(transcript)|go:"GO:0000812"(Swr1 complex)|go:"GO:0005634"(nucleus)|go:"GO:0006338"(chromatin remodeling)|interpro:IPR020195|sgd:YLR385C(identity)	refseq:NP_002266.2|ensembl:ENSG00000171346(gene)|ensembl:ENST00000254043(transcript)|ensembl:ENST00000393976(transcript)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0008544"(epidermis development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097110"(scaffold protein binding)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR039008|mint:P19012|reactome:R-HSA-6805567|reactome:R-HSA-6809371|entrezgene/locuslink:3866(identity)	-	crc64:92CCE2FF3DCE72F1	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:7DWWay9S3JHtIRpmJHyHeELBg5M559292	rogid:WrZQBYQvrWcfrR5ojWXrXp6spPE9606	intact-crc:D13DFF21A8F793CC|rigid:T1Rwcy8baI7wPgKD8u8cgVBiNEw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q13137	uniprotkb:Q06707	intact:EBI-739580|uniprotkb:B4DDC4|uniprotkb:E7ENK0|uniprotkb:Q53FQ5|uniprotkb:Q53HB5|uniprotkb:Q6IBN9|uniprotkb:Q9BTF7|uniprotkb:B2RBT0|ensembl:ENSP00000258947|uniprotkb:B4E0C0|uniprotkb:E7ETP5|uniprotkb:B4DDT4|uniprotkb:B4DP36|uniprotkb:E9PBE5	intact:EBI-32671|uniprotkb:D6VZ20|ensemblfungi:YLR385C	psi-mi:caco2_human(display_long)|uniprotkb:CALCOCO2(gene name)|psi-mi:CALCOCO2(display_short)|uniprotkb:NDP52(gene name synonym)|uniprotkb:Nuclear domain 10 protein NDP52(gene name synonym)|uniprotkb:Antigen nuclear dot 52 kDa protein(gene name synonym)|uniprotkb:Nuclear dot protein 52(gene name synonym)	psi-mi:swc7_yeast(display_long)|uniprotkb:SWC7(gene name)|psi-mi:SWC7(display_short)|uniprotkb:AWS1(gene name synonym)|uniprotkb:YLR385C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11546377|imex:IM-24995-2537	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001248319.1|refseq:NP_001248320.1|refseq:NP_001248322.1|refseq:NP_005822.1|ensembl:ENSG00000136436(gene)|ensembl:ENST00000258947(transcript)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016032"(viral process)|go:"GO:0016605"(PML body)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0098792"(xenophagy)|go:"GO:1901098"(positive regulation of autophagosome maturation)|interpro:IPR041611|interpro:IPR041641|mint:Q13137|rcsb pdb:2MXP|rcsb pdb:3VVV|rcsb pdb:3VVW|rcsb pdb:4GXL|rcsb pdb:4HAN|rcsb pdb:4XKL|rcsb pdb:5AAQ|rcsb pdb:5Z7A|rcsb pdb:5Z7L|refseq:NP_001248324.1|dip:DIP-57534N|entrezgene/locuslink:10241(identity)	refseq:NP_013489.1|sgd:S000004377|dip:DIP-4645N|mint:Q06707|ensemblfungi:YLR385C(gene)|ensemblfungi:YLR385C_mRNA(transcript)|go:"GO:0000812"(Swr1 complex)|go:"GO:0005634"(nucleus)|go:"GO:0006338"(chromatin remodeling)|interpro:IPR020195|sgd:YLR385C(identity)	-	crc64:609B121DA1A9DCB8	crc64:92CCE2FF3DCE72F1	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:N/GPJUGBK+Dh5Cg+csmafphuo9M9606	rogid:7DWWay9S3JHtIRpmJHyHeELBg5M559292	intact-crc:C1A66569EF2BADD3|rigid:EY1ZjaIkZK52NNMpTnv/YZWpAdU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O43765	uniprotkb:Q06810	intact:EBI-347996|ensembl:ENSP00000221566|ensembl:ENSP00000503397|ensembl:ENSP00000504495|uniprotkb:Q9BTZ9|intact:EBI-1045243|uniprotkb:Q6FIA9|uniprotkb:D6W610	intact:EBI-2068557|uniprotkb:D6W479|uniprotkb:Q6B149|ensemblfungi:YPR075C	psi-mi:sgta_human(display_long)|uniprotkb:SGTA(gene name)|psi-mi:SGTA(display_short)|uniprotkb:SGT(gene name synonym)|uniprotkb:Alpha-SGT(gene name synonym)|uniprotkb:Vpu-binding protein(gene name synonym)|uniprotkb:SGT1(gene name synonym)	psi-mi:opy2_yeast(display_long)|uniprotkb:OPY2(gene name)|psi-mi:OPY2(display_short)|uniprotkb:Overproduction-induced pheromone-resistant protein 2(gene name synonym)|uniprotkb:YPR075C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11546386|imex:IM-24995-2538	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:4CPG|rcsb pdb:4GOD|rcsb pdb:4GOE|rcsb pdb:4GOF|reactome:R-HSA-9609523|rcsb pdb:2VYI|ensembl:ENSG00000104969(gene)|ensembl:ENST00000221566(transcript)|ensembl:ENST00000676943(transcript)|ensembl:ENST00000677149(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072380"(TRC complex)|go:"GO:0098850"(extrinsic component of synaptic vesicle membrane)|go:"GO:1903070"(negative regulation of ER-associated ubiquitin-dependent protein catabolic process)|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)|go:"GO:1903646"(positive regulation of chaperone-mediated protein folding)|go:"GO:1904288"(BAT3 complex binding)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR032374|mint:O43765|refseq:XP_011526480.1|refseq:NP_003012.1|entrezgene/locuslink:6449(identity)	refseq:NP_015400.1|sgd:S000006279|interpro:IPR018571|mint:Q06810|ensemblfungi:YPR075C(gene)|ensemblfungi:YPR075C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000751"(mitotic cell cycle G1 arrest in response to pheromone)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007231"(osmosensory signaling pathway)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:1900436"(positive regulation of filamentous growth of a population of unicellular organisms in response to starvation)|sgd:YPR075C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:r/Cyj4UJk/cS8QdrbjhTZMPCigI9606	rogid:avNmi6o7WtIkxIyUvhoboBXL8sc559292	intact-crc:50C25E490B852601|rigid:TCNluPxabzIjedlLFatvZqtighs	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8IYA8	uniprotkb:Q06819	intact:EBI-8638439|intact:EBI-28969497|ensembl:ENSP00000296449|ensembl:ENSP00000391788|ensembl:ENSP00000407837|uniprotkb:C9JJL0|uniprotkb:Q96LP7|intact:MINT-8162095|uniprotkb:Q05DG9	intact:EBI-166|ensemblfungi:YPR082C|uniprotkb:D6W484	psi-mi:iho1_human(display_long)|uniprotkb:IHO1(gene name)|psi-mi:IHO1(display_short)|uniprotkb:CCDC36(gene name synonym)|uniprotkb:Cancer/testis antigen 74(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 36(gene name synonym)	psi-mi:dib1_yeast(display_long)|uniprotkb:DIB1(gene name)|psi-mi:DIB1(display_short)|uniprotkb:CDH1(gene name synonym)|uniprotkb:SNU16(gene name synonym)|uniprotkb:YPR082C(locus name)|uniprotkb:P9513.12(orf name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11546395|imex:IM-24995-2539	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000296449|ensembl:ENST00000366429|ensembl:ENSP00000403700|ensembl:ENSP00000391788|ensembl:ENSP00000407837|ensembl:ENSG00000173421(gene)|ensembl:ENST00000296449(transcript)|ensembl:ENST00000438782(transcript)|ensembl:ENST00000452691(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0006310"(DNA recombination)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0042138"(meiotic DNA double-strand break formation)|go:"GO:0048477"(oogenesis)|go:"GO:0060629"(regulation of homologous chromosome segregation)|interpro:IPR031529|mint:Q8IYA8|refseq:XP_011531974.1|refseq:XP_011531975.1|refseq:NP_001128669.1|refseq:NP_835467.2|refseq:XP_006713187.1|entrezgene/locuslink:339834(identity)	refseq:NP_015407.1|sgd:S000006286|ensemblfungi:YPR082C(gene)|ensemblfungi:YPR082C_mRNA(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005682"(U5 snRNP)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|interpro:IPR004123(mRNA splicing factor, thioredoxin-like U5 snRNP)|interpro:IPR036249|rcsb pdb:3JCM|rcsb pdb:5GAN|rcsb pdb:5GAP|rcsb pdb:5NRL|rcsb pdb:5ZWM|rcsb pdb:5ZWO|dip:DIP-1289N|sgd:YPR082C(identity)	-	comment:mint	crc64:B8C11278571C57E5	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:+TNQLExkhmC1NWqsE240Cx7zFVU9606	rogid:mRibIpinKPlRNdh60VJj/Z0tjUc559292	intact-crc:BD5DFBEF760F7579|rigid:4GejNbKKpIULMOfZDB67JAlCfpM	false	sufficient binding region:11-594	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8TBB1	uniprotkb:Q06819	intact:EBI-739832|uniprotkb:Q4W5K7|uniprotkb:Q8N4C2|uniprotkb:Q96MJ7|uniprotkb:Q9BY20|ensembl:ENSP00000263925	intact:EBI-166|ensemblfungi:YPR082C|uniprotkb:D6W484	psi-mi:lnx1_human(display_long)|uniprotkb:LNX1(gene name)|psi-mi:LNX1(display_short)|uniprotkb:LNX(gene name synonym)|uniprotkb:Numb-binding protein 1(gene name synonym)|uniprotkb:Ligand of Numb-protein X 1(gene name synonym)|uniprotkb:PDZ domain-containing RING finger protein 2(gene name synonym)|uniprotkb:PDZRN2(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase LNX(gene name synonym)|uniprotkb:UNQ574/PRO1136(orf name)	psi-mi:dib1_yeast(display_long)|uniprotkb:DIB1(gene name)|psi-mi:DIB1(display_short)|uniprotkb:CDH1(gene name synonym)|uniprotkb:SNU16(gene name synonym)|uniprotkb:YPR082C(locus name)|uniprotkb:P9513.12(orf name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11546406|imex:IM-24995-2540	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001119800.1|refseq:NP_116011.2|refseq:XP_005265842.1|refseq:XP_016864265.1|ensembl:ENSG00000072201(gene)|ensembl:ENST00000263925(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR036034|mint:Q8TBB1|rcsb pdb:3B76|rcsb pdb:5H7R|rcsb pdb:5H7S|reactome:R-HSA-983168|entrezgene/locuslink:84708(identity)	refseq:NP_015407.1|sgd:S000006286|ensemblfungi:YPR082C(gene)|ensemblfungi:YPR082C_mRNA(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005682"(U5 snRNP)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|interpro:IPR004123(mRNA splicing factor, thioredoxin-like U5 snRNP)|interpro:IPR036249|rcsb pdb:3JCM|rcsb pdb:5GAN|rcsb pdb:5GAP|rcsb pdb:5NRL|rcsb pdb:5ZWM|rcsb pdb:5ZWO|dip:DIP-1289N|sgd:YPR082C(identity)	-	-	crc64:B8C11278571C57E5	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:tWvePnVxh9yxWl8nQd3KZhCSKKo9606	rogid:mRibIpinKPlRNdh60VJj/Z0tjUc559292	intact-crc:D07AA4002949FFFC|rigid:Z62+WYYqaD8KbDFQTEubq/DK/Pg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q06819	uniprotkb:Q9BUT1	intact:EBI-166|ensemblfungi:YPR082C|uniprotkb:D6W484	intact:EBI-6137689|uniprotkb:A8K295|uniprotkb:B4DUF6|uniprotkb:Q503A0|uniprotkb:Q6IA46|uniprotkb:Q6UWD3|uniprotkb:Q9H8S8|uniprotkb:Q9NRX8|ensembl:ENSP00000296424	psi-mi:dib1_yeast(display_long)|uniprotkb:DIB1(gene name)|psi-mi:DIB1(display_short)|uniprotkb:CDH1(gene name synonym)|uniprotkb:SNU16(gene name synonym)|uniprotkb:YPR082C(locus name)|uniprotkb:P9513.12(orf name)	psi-mi:bdh2_human(display_long)|uniprotkb:SDR15C1(gene name synonym)|uniprotkb:Short chain dehydrogenase/reductase family 15C member 1(gene name synonym)|uniprotkb:UNQ6308/PRO20933(orf name)|uniprotkb:BDH2(gene name)|psi-mi:BDH2(display_short)|uniprotkb:DHRS6(gene name synonym)|uniprotkb:Dehydrogenase/reductase SDR family member 6(gene name synonym)|uniprotkb:Oxidoreductase UCPA(gene name synonym)|uniprotkb:R-beta-hydroxybutyrate dehydrogenase(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11546415|imex:IM-24995-2541	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015407.1|sgd:S000006286|ensemblfungi:YPR082C(gene)|ensemblfungi:YPR082C_mRNA(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005682"(U5 snRNP)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|interpro:IPR004123(mRNA splicing factor, thioredoxin-like U5 snRNP)|interpro:IPR036249|rcsb pdb:3JCM|rcsb pdb:5GAN|rcsb pdb:5GAP|rcsb pdb:5NRL|rcsb pdb:5ZWM|rcsb pdb:5ZWO|dip:DIP-1289N|sgd:YPR082C(identity)	refseq:XP_011530430.1|refseq:NP_064524.3|refseq:XP_016863951.1|ensembl:ENSG00000164039(gene)|ensembl:ENST00000296424(transcript)|go:"GO:0003858"(3-hydroxybutyrate dehydrogenase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0016616"(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|go:"GO:0016628"(oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor)|go:"GO:0019290"(siderophore biosynthetic process)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0042168"(heme metabolic process)|go:"GO:0051287"(NAD binding)|go:"GO:0055072"(iron ion homeostasis)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR020904|interpro:IPR036291|rcsb pdb:2AG5|reactome:R-HSA-77111|entrezgene/locuslink:56898(identity)	-	crc64:B8C11278571C57E5	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:mRibIpinKPlRNdh60VJj/Z0tjUc559292	rogid:jo1enuFW27NpCn5SWMEBipbUKXA9606	intact-crc:94C029D0A4080BC6|rigid:PXBSTSrHAtEBVhKdNzJ15cl3Y9w	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O95544	uniprotkb:Q06892	intact:EBI-743949|uniprotkb:Q9H931|uniprotkb:A8K296|uniprotkb:A6NNN3|uniprotkb:B7Z434|uniprotkb:F5GXR5|uniprotkb:Q5QPS4|uniprotkb:Q9H2P2|ensembl:ENSP00000341679|ensembl:ENSP00000344340	intact:EBI-13701|uniprotkb:Q08928|uniprotkb:D6W3I1|ensemblfungi:YPL188W	psi-mi:nadk_human(display_long)|uniprotkb:"Poly(P)/ATP NAD kinase"(gene name synonym)|uniprotkb:NADK(gene name)|psi-mi:NADK(display_short)	psi-mi:pos5_yeast(display_long)|uniprotkb:POS5(gene name)|psi-mi:POS5(display_short)|uniprotkb:YPL188W(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11546424|imex:IM-24995-2542	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001185922.1|refseq:NP_001185923.1|refseq:NP_001185924.1|refseq:NP_075394.3|refseq:XP_005244835.1|refseq:XP_006710900.1|ensembl:ENSG00000008130(gene)|ensembl:ENST00000341426(transcript)|ensembl:ENST00000341991(transcript)|go:"GO:0003951"(NAD+ kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006741"(NADP biosynthetic process)|go:"GO:0016310"(phosphorylation)|go:"GO:0019674"(NAD metabolic process)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046872"(metal ion binding)|interpro:IPR002504(ATP-NAD/AcoX kinase)|interpro:IPR016064(ATP-NAD kinase, PpnK-type)|interpro:IPR017437(ATP-NAD kinase, PpnK-type, all-beta)|interpro:IPR017438(ATP-NAD kinase, PpnK-type, alpha/beta)|mint:O95544|rcsb pdb:3PFN|reactome:R-HSA-196807|entrezgene/locuslink:65220(identity)	sgd:S000006109|refseq:NP_015136.1|ensemblfungi:YPL188W(gene)|ensemblfungi:YPL188W_mRNA(transcript)|go:"GO:0003951"(NAD+ kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006741"(NADP biosynthetic process)|go:"GO:0019674"(NAD metabolic process)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0042736"(NADH kinase activity)|interpro:IPR002504(ATP-NAD/AcoX kinase)|interpro:IPR016064(ATP-NAD kinase, PpnK-type)|interpro:IPR017437(ATP-NAD kinase, PpnK-type, all-beta)|interpro:IPR017438(ATP-NAD kinase, PpnK-type, alpha/beta)|rcsb pdb:3AFO|dip:DIP-5503N|sgd:YPL188W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:XPfRviZiKsV+1JOUi7BsMrIa3M49606	rogid:4n8TcpxeCYBUCHDHMqmxXeNsiGg559292	intact-crc:61C512F1AC5744BE|rigid:UBiQvKC4Vp5FyW8BDGGA5N6aQmM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8N9N5-2	uniprotkb:Q06892	intact:EBI-11524452|ensembl:ENSP00000347125	intact:EBI-13701|uniprotkb:Q08928|uniprotkb:D6W3I1|ensemblfungi:YPL188W	psi-mi:q8n9n5-2(display_long)|uniprotkb:BANP(gene name)|psi-mi:BANP(display_short)|uniprotkb:BEN domain-containing protein 1(gene name synonym)|uniprotkb:BEND1(gene name synonym)|uniprotkb:Btg3-associated nuclear protein(gene name synonym)|uniprotkb:SMAR1(gene name synonym)|uniprotkb:Scaffold/matrix-associated region-1-binding protein(gene name synonym)	psi-mi:pos5_yeast(display_long)|uniprotkb:POS5(gene name)|psi-mi:POS5(display_short)|uniprotkb:YPL188W(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11546433|imex:IM-24995-2543	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000172530(gene)|ensembl:ENST00000355022(transcript)|intact:EBI-744695(isoform-parent)|uniprotkb:Q8N9N5-2(isoform-parent)|entrezgene/locuslink:54971(identity)	sgd:S000006109|refseq:NP_015136.1|ensemblfungi:YPL188W(gene)|ensemblfungi:YPL188W_mRNA(transcript)|go:"GO:0003951"(NAD+ kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006741"(NADP biosynthetic process)|go:"GO:0019674"(NAD metabolic process)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0042736"(NADH kinase activity)|interpro:IPR002504(ATP-NAD/AcoX kinase)|interpro:IPR016064(ATP-NAD kinase, PpnK-type)|interpro:IPR017437(ATP-NAD kinase, PpnK-type, all-beta)|interpro:IPR017438(ATP-NAD kinase, PpnK-type, alpha/beta)|rcsb pdb:3AFO|dip:DIP-5503N|sgd:YPL188W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:ESe6iCAhvq+i57fQHz3rGyg6UOo9606	rogid:4n8TcpxeCYBUCHDHMqmxXeNsiGg559292	intact-crc:88F8C6669D7C85F4|rigid:fkIWPJt/JzO5lZHgnnu/7NAaj7s	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q06707	uniprotkb:P37198	intact:EBI-32671|uniprotkb:D6VZ20|ensemblfungi:YLR385C	intact:EBI-347978|intact:EBI-28983799|ensembl:ENSP00000305503|ensembl:ENSP00000407331|ensembl:ENSP00000471191|ensembl:ENSP00000473192|uniprotkb:Q6GTM2|uniprotkb:Q503A4|uniprotkb:Q96C43|uniprotkb:Q9NSL1|uniprotkb:B3KWU5	psi-mi:swc7_yeast(display_long)|uniprotkb:SWC7(gene name)|psi-mi:SWC7(display_short)|uniprotkb:AWS1(gene name synonym)|uniprotkb:YLR385C(locus name)	psi-mi:nup62_human(display_long)|uniprotkb:NUP62(gene name)|psi-mi:NUP62(display_short)|uniprotkb:62 kDa nucleoporin(gene name synonym)|uniprotkb:Nucleoporin Nup62(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11546368|imex:IM-24995-2536	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013489.1|sgd:S000004377|dip:DIP-4645N|mint:Q06707|ensemblfungi:YLR385C(gene)|ensemblfungi:YLR385C_mRNA(transcript)|go:"GO:0000812"(Swr1 complex)|go:"GO:0005634"(nucleus)|go:"GO:0006338"(chromatin remodeling)|interpro:IPR020195|sgd:YLR385C(identity)	refseq:NP_714941.1|ensembl:ENSG00000213024(gene)|ensembl:ENST00000352066(transcript)|ensembl:ENST00000422090(transcript)|ensembl:ENST00000596217(transcript)|ensembl:ENST00000597029(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005642"(annulate lamellae)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007100"(mitotic centrosome separation)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007569"(cell aging)|go:"GO:0008219"(cell death)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0003682"(chromatin binding)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0019894"(kinesin binding)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042306"(regulation of protein import into nucleus)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043069"(negative regulation of programmed cell death)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045742"(positive regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046578"(regulation of Ras protein signal transduction)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0046601"(positive regulation of centriole replication)|go:"GO:0051028"(mRNA transport)|go:"GO:0051425"(PTB domain binding)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0072686"(mitotic spindle)|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|go:"GO:0090543"(Flemming body)|go:"GO:0098534"(centriole assembly)|go:"GO:1903438"(positive regulation of mitotic cytokinetic process)|go:"GO:1904781"(positive regulation of protein localization to centrosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR007758(Nucleoporin, Nsp1-like, C-terminal)|interpro:IPR026010|interpro:IPR033072|mint:P37198|rcsb pdb:2H4D|rcsb pdb:5IJN|rcsb pdb:5IJO|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|refseq:NP_714940.1|refseq:NP_001180286.1|refseq:NP_036478.2|refseq:NP_057637.2|ensembl:ENSP00000305503|ensembl:ENSP00000407331|ensembl:ENSP00000471191|ensembl:ENSP00000473192|dip:DIP-29749N|entrezgene/locuslink:23636(identity)	-	crc64:92CCE2FF3DCE72F1	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:7DWWay9S3JHtIRpmJHyHeELBg5M559292	rogid:v7mvKvTtVEnLMwcpUZIcdAzge009606	intact-crc:EB5346DBCFA41732|rigid:LmH67keCrwmZ13ODEvS29CWwdkw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q07379	uniprotkb:P35520	intact:EBI-2342994|uniprotkb:D6VRT9|ensemblfungi:YDL057W	intact:EBI-740135|uniprotkb:Q99425|uniprotkb:Q9BWC5|uniprotkb:B2R993|uniprotkb:D3DSK4|intact:EBI-14245939|ensembl:ENSP00000344460|ensembl:ENSP00000352643|ensembl:ENSP00000381225|ensembl:ENSP00000381231	psi-mi:yd057_yeast(display_long)|uniprotkb:YDL057W(locus name)	psi-mi:cbs_human(display_long)|uniprotkb:CBS(gene name)|psi-mi:CBS(display_short)|uniprotkb:Serine sulfhydrase(gene name synonym)|uniprotkb:Beta-thionase(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11546453|imex:IM-24995-2545	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002215|refseq:NP_010226.1|interpro:IPR022742|interpro:IPR029058|ensemblfungi:YDL057W(gene)|ensemblfungi:YDL057W_mRNA(transcript)|go:"GO:0016020"(membrane)|go:"GO:0016298"(lipase activity)|sgd:YDL057W(identity)	refseq:NP_000062.1|refseq:NP_001171479.1|refseq:NP_001171480.1|ensembl:ENSG00000160200(gene)|ensembl:ENST00000352178(transcript)|ensembl:ENST00000359624(transcript)|ensembl:ENST00000398158(transcript)|go:"GO:0004122"(cystathionine beta-synthase activity)|ensembl:ENST00000398165(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006535"(cysteine biosynthetic process from serine)|go:"GO:0006563"(L-serine metabolic process)|go:"GO:0006565"(L-serine catabolic process)|go:"GO:0019343"(cysteine biosynthetic process via cystathionine)|go:"GO:0019344"(cysteine biosynthetic process)|go:"GO:0019346"(transsulfuration)|go:"GO:0019448"(L-cysteine catabolic process)|go:"GO:0019825"(oxygen binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0020037"(heme binding)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042262"(DNA protection)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043418"(homocysteine catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0050421"("nitrite reductase (NO-forming) activity")|go:"GO:0050667"(homocysteine metabolic process)|go:"GO:0070025"(carbon monoxide binding)|go:"GO:0070026"(nitric oxide binding)|go:"GO:0070814"(hydrogen sulfide biosynthetic process)|go:"GO:0072341"(modified amino acid binding)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR001216(Cysteine synthase/cystathionine beta-synthase P-phosphate-binding site)|interpro:IPR001926(Pyridoxal phosphate-dependent enzyme, beta subunit)|interpro:IPR005857(Cystathionine beta-synthase)|interpro:IPR036052|mint:P35520|rcsb pdb:1JBQ|rcsb pdb:1M54|rcsb pdb:4COO|rcsb pdb:4L0D|rcsb pdb:4L27|rcsb pdb:4L28|rcsb pdb:4L3V|rcsb pdb:4PCU|rcsb pdb:4UUU|rcsb pdb:5MMS|reactome:R-HSA-1614603|reactome:R-HSA-2408508|refseq:XP_011528079.1|refseq:XP_011528083.1|refseq:XP_011528084.1|refseq:XP_011544396.1|refseq:XP_011544397.1|refseq:XP_011544399.1|refseq:XP_011544400.1|refseq:XP_011544401.1|refseq:NP_001307227.1|refseq:NP_001308002.1|refseq:XP_016883700.1|refseq:XP_016883701.1|refseq:XP_016883702.1|refseq:XP_016883703.1|refseq:XP_016883704.1|refseq:XP_016883705.1|refseq:XP_016883706.1|refseq:XP_016883707.1|refseq:XP_016883978.1|refseq:XP_016883979.1|refseq:XP_016883980.1|refseq:XP_016883981.1|entrezgene/locuslink:875(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:U0Sf+t16Ti+vYEOEePrGjlqflhQ559292	rogid:f9eo0cPOHppVY7Nqejag3YyK18s9606	intact-crc:787A03C439F3F803|rigid:T9PY+yIXzgaFi35EqGJeQoGF1As	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q07379	uniprotkb:Q08379	intact:EBI-2342994|uniprotkb:D6VRT9|ensemblfungi:YDL057W	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	psi-mi:yd057_yeast(display_long)|uniprotkb:YDL057W(locus name)	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11546442|imex:IM-24995-2544	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002215|refseq:NP_010226.1|interpro:IPR022742|interpro:IPR029058|ensemblfungi:YDL057W(gene)|ensemblfungi:YDL057W_mRNA(transcript)|go:"GO:0016020"(membrane)|go:"GO:0016298"(lipase activity)|sgd:YDL057W(identity)	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N|entrezgene/locuslink:2801(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2017/05/26	rogid:U0Sf+t16Ti+vYEOEePrGjlqflhQ559292	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	intact-crc:07BE981405AB7E36|rigid:t/tkMK4SbkVX9DfY0HE+ECrpGW4	false	-	sufficient binding region:383-1002	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q07379	uniprotkb:Q9HCM9-2	intact:EBI-2342994|uniprotkb:D6VRT9|ensemblfungi:YDL057W	intact:EBI-11523450|ensembl:ENSP00000365847|ensembl:ENSP00000373095|ensembl:ENSP00000373097|ensembl:ENSP00000379797|ensembl:ENSP00000379800|ensembl:ENSP00000383486|ensembl:ENSP00000387445|ensembl:ENSP00000389198|ensembl:ENSP00000389852|ensembl:ENSP00000392130|ensembl:ENSP00000394353|ensembl:ENSP00000396986|ensembl:ENSP00000398956|ensembl:ENSP00000401071|ensembl:ENSP00000401184|ensembl:ENSP00000404340|ensembl:ENSP00000404904|ensembl:ENSP00000411582|ensembl:ENSP00000412743|ensembl:ENSP00000414525|ensembl:ENSP00000415259	psi-mi:yd057_yeast(display_long)|uniprotkb:YDL057W(locus name)	psi-mi:q9hcm9-2(display_long)|uniprotkb:TRIM39(gene name)|psi-mi:TRIM39(display_short)|uniprotkb:RING finger protein 23(gene name synonym)|uniprotkb:RNF23(gene name synonym)|uniprotkb:TFP(gene name synonym)|uniprotkb:Testis-abundant finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 39(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM39(gene name synonym)|uniprotkb:TIM39beta(isoform synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11546471|imex:IM-24995-2547	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002215|refseq:NP_010226.1|interpro:IPR022742|interpro:IPR029058|ensemblfungi:YDL057W(gene)|ensemblfungi:YDL057W_mRNA(transcript)|go:"GO:0016020"(membrane)|go:"GO:0016298"(lipase activity)|sgd:YDL057W(identity)	intact:EBI-739510(isoform-parent)|ensembl:ENSG00000204599(gene)|ensembl:ENSG00000206495(gene)|ensembl:ENSG00000224994(gene)|ensembl:ENSG00000226437(gene)|ensembl:ENSG00000229929(gene)|ensembl:ENSG00000230308(gene)|ensembl:ENSG00000232839(gene)|ensembl:ENST00000376659(transcript)|ensembl:ENST00000383601(transcript)|ensembl:ENST00000383603(transcript)|ensembl:ENST00000396548(transcript)|ensembl:ENST00000396551(transcript)|ensembl:ENST00000400644(transcript)|ensembl:ENST00000414015(transcript)|ensembl:ENST00000419790(transcript)|ensembl:ENST00000430502(transcript)|ensembl:ENST00000431272(transcript)|ensembl:ENST00000433900(transcript)|ensembl:ENST00000438076(transcript)|ensembl:ENST00000438859(transcript)|ensembl:ENST00000440117(transcript)|ensembl:ENST00000443109(transcript)|ensembl:ENST00000446397(transcript)|ensembl:ENST00000449318(transcript)|ensembl:ENST00000450778(transcript)|ensembl:ENST00000451132(transcript)|ensembl:ENST00000452705(transcript)|ensembl:ENST00000458607(transcript)|uniprotkb:Q9HCM9-2(isoform-parent)|entrezgene/locuslink:56658(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:U0Sf+t16Ti+vYEOEePrGjlqflhQ559292	rogid:UfSn2+IVRxtGomVeDGdZpL7mz5I9606	intact-crc:5B603704861E1E19|rigid:LujSrb70dn9603zLaNySPeB9lTQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q07379	uniprotkb:Q9Y2D8	intact:EBI-2342994|uniprotkb:D6VRT9|ensemblfungi:YDL057W	intact:EBI-2212028|uniprotkb:B4DFE3|uniprotkb:J3KR02|uniprotkb:A8K8W0|uniprotkb:D3DT13|uniprotkb:Q6P2P8|uniprotkb:Q6ULS1|uniprotkb:Q7L168|uniprotkb:Q9UIX0|intact:EBI-10964529|ensembl:ENSP00000340279	psi-mi:yd057_yeast(display_long)|uniprotkb:YDL057W(locus name)	psi-mi:adip_human(display_long)|uniprotkb:SSX2IP(gene name)|psi-mi:SSX2IP(display_short)|uniprotkb:KIAA0923(gene name synonym)|uniprotkb:Afadin DIL domain-interacting protein(gene name synonym)|uniprotkb:SSX2-interacting protein(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11546481|imex:IM-24995-2548	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002215|refseq:NP_010226.1|interpro:IPR022742|interpro:IPR029058|ensemblfungi:YDL057W(gene)|ensemblfungi:YDL057W_mRNA(transcript)|go:"GO:0016020"(membrane)|go:"GO:0016298"(lipase activity)|sgd:YDL057W(identity)	refseq:XP_011538912.1|refseq:NP_001159765.1|refseq:NP_001159766.1|refseq:NP_001159767.1|refseq:NP_001159889.1|refseq:NP_054740.3|refseq:XP_005270484.1|refseq:XP_005270485.1|refseq:XP_006710394.1|refseq:XP_016855723.1|ensembl:ENSG00000117155(gene)|ensembl:ENST00000342203(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005912"(adherens junction)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031252"(cell leading edge)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0035735"(intraciliary transport involved in cilium assembly)|go:"GO:0036064"(ciliary basal body)|go:"GO:0060271"(cilium assembly)|go:"GO:2000145"(regulation of cell motility)|interpro:IPR021622|mint:Q9Y2D8|entrezgene/locuslink:117178(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:U0Sf+t16Ti+vYEOEePrGjlqflhQ559292	rogid:E0VeMRF9SrpQKSJFP01XEbMjeF89606	intact-crc:50C73C26CB347629|rigid:LpBusrQr3b/2e4C6qtgDdqgBuNo	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q07379	uniprotkb:Q9Y2J4	intact:EBI-2342994|uniprotkb:D6VRT9|ensemblfungi:YDL057W	intact:EBI-746752|intact:EBI-28986657|ensembl:ENSP00000409999|uniprotkb:Q53EP1|uniprotkb:Q96F99|uniprotkb:Q9UKB4|uniprotkb:A8K6F1|uniprotkb:B7Z5Q1|uniprotkb:E9PHW3	psi-mi:yd057_yeast(display_long)|uniprotkb:YDL057W(locus name)	psi-mi:amol2_human(display_long)|uniprotkb:Leman coiled-coil protein(gene name synonym)|uniprotkb:AMOTL2(gene name)|psi-mi:AMOTL2(display_short)|uniprotkb:KIAA0989(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11546490|imex:IM-24995-2549	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002215|refseq:NP_010226.1|interpro:IPR022742|interpro:IPR029058|ensemblfungi:YDL057W(gene)|ensemblfungi:YDL057W_mRNA(transcript)|go:"GO:0016020"(membrane)|go:"GO:0016298"(lipase activity)|sgd:YDL057W(identity)	refseq:NP_001265612.1|refseq:NP_001265614.1|ensembl:ENSG00000114019(gene)|refseq:XP_006713717.1|refseq:NP_057285.3|refseq:XP_011511183.1|ensembl:ENST00000422605(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0003365"(establishment of cell polarity involved in ameboidal cell migration)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0035329"(hippo signaling)|go:"GO:0055037"(recycling endosome)|interpro:IPR009114(Angiomotin)|interpro:IPR024646|mint:Q9Y2J4|reactome:R-HSA-2028269|refseq:XP_016862069.1|refseq:XP_016862070.1|refseq:XP_016862071.1|ensembl:ENST00000249883|ensembl:ENSP00000249883|ensembl:ENSP00000409999|ensembl:ENST00000513145|ensembl:ENSP00000425475|ensembl:ENST00000514516|ensembl:ENSP00000424765|dip:DIP-57510N|entrezgene/locuslink:51421(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:U0Sf+t16Ti+vYEOEePrGjlqflhQ559292	rogid:SHtKAcLLnTpSSLwVE7yQ1WECoZk9606	intact-crc:15AE5EFAA6693268|rigid:lshhUmMY13Dj00iSsAILwXja8W8	false	-	sufficient binding region:314-779	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:A0A024R0Y4	uniprotkb:Q07540	intact:EBI-11523730|ensembl:ENSP00000477709|ensembl:ENSP00000478363|ensembl:ENSP00000481091	intact:EBI-2206814|uniprotkb:D6VRN0|ensemblfungi:YDL120W	psi-mi:a0a024r0y4_human(display_long)|uniprotkb:TADA2A(gene name)|psi-mi:TADA2A(display_short)|uniprotkb:TADA2L(gene name synonym)|uniprotkb:hCG_28187(orf name)	psi-mi:frda_yeast(display_long)|uniprotkb:YFH1(gene name)|psi-mi:YFH1(display_short)|uniprotkb:YDL120W(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11546501|imex:IM-24995-2550	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001159577.2|refseq:NP_001479.4|ensembl:ENSG00000276234(gene)|ensembl:ENST00000612272(transcript)|ensembl:ENST00000615182(transcript)|ensembl:ENST00000620628(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031063"(regulation of histone deacetylation)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0035065"(regulation of histone acetylation)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090043"(regulation of tubulin deacetylation)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016827(Transcriptional adaptor 2)|interpro:IPR017884|interpro:IPR017930|interpro:IPR036388|interpro:IPR041983|interpro:IPR043145|entrezgene/locuslink:6871(identity)	dip:DIP-7485N|refseq:NP_010163.1|sgd:S000002278|mint:Q07540|ensemblfungi:YDL120W(gene)|ensemblfungi:YDL120W_mRNA(transcript)|go:"GO:0004322"(ferroxidase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006121"(mitochondrial electron transport, succinate to ubiquinone)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0006783"(heme biosynthetic process)|go:"GO:0006811"(ion transport)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008199"(ferric iron binding)|go:"GO:0010040"("response to iron(II) ion")|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0018283"(iron incorporation into metallo-sulfur cluster)|go:"GO:0034986"(iron chaperone activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|interpro:IPR002908(Frataxin-like)|interpro:IPR017789(Frataxin)|interpro:IPR020895|interpro:IPR036524|rcsb pdb:2FQL|rcsb pdb:2GA5|rcsb pdb:3OEQ|rcsb pdb:3OER|rcsb pdb:4EC2|rcsb pdb:5T0V|rcsb pdb:5TRE|reactome:R-SCE-1268020|reactome:R-SCE-1362409|go:"GO:0008198"(ferrous iron binding)|sgd:YDL120W(identity)	-	-	crc64:AB1FF7478EF0E5D6	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:IGh7vC68gMLe+tAVGM4gc0rzc6Y9606	rogid:4UcroTodEXb/5+xHGpnXDXf/rd8559292	intact-crc:9E6A6ED438B00B59|rigid:ATP/kj+Z6lPImhni88ySl6WER7c	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q92609	uniprotkb:Q07540	intact:EBI-742381|uniprotkb:A6NP25|intact:EBI-28978959|ensembl:ENSP00000253692|ensembl:ENSP00000398127|uniprotkb:C9JP52	intact:EBI-2206814|uniprotkb:D6VRN0|ensemblfungi:YDL120W	psi-mi:tbcd5_human(display_long)|uniprotkb:TBC1D5(gene name)|psi-mi:TBC1D5(display_short)|uniprotkb:KIAA0210(gene name synonym)	psi-mi:frda_yeast(display_long)|uniprotkb:YFH1(gene name)|psi-mi:YFH1(display_short)|uniprotkb:YDL120W(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11546510|imex:IM-24995-2551	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000253692|ensembl:ENSP00000398127|ensembl:ENSP00000402935|ensembl:ENST00000446818|refseq:NP_055559.1|refseq:XP_011532586.1|refseq:XP_011532583.1|refseq:XP_011532585.1|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005776"(autophagosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006914"(autophagy)|go:"GO:0010008"(endosome membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0030904"(retromer complex)|go:"GO:0035612"(AP-2 adaptor complex binding)|ensembl:ENSG00000131374(gene)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042594"(response to starvation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:1905394"(retromer complex binding)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR035969|mint:Q92609|rcsb pdb:5GTU|ensembl:ENST00000253692(transcript)|ensembl:ENST00000429383(transcript)|go:"GO:0002092"(positive regulation of receptor internalization)|refseq:NP_001127853.1|refseq:XP_006713493.1|refseq:XP_016863041.1|refseq:XP_016863042.1|refseq:XP_016863043.1|refseq:XP_016863044.1|refseq:XP_016863045.1|refseq:XP_016863046.1|entrezgene/locuslink:9779(identity)	dip:DIP-7485N|refseq:NP_010163.1|sgd:S000002278|mint:Q07540|ensemblfungi:YDL120W(gene)|ensemblfungi:YDL120W_mRNA(transcript)|go:"GO:0004322"(ferroxidase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006121"(mitochondrial electron transport, succinate to ubiquinone)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0006783"(heme biosynthetic process)|go:"GO:0006811"(ion transport)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008199"(ferric iron binding)|go:"GO:0010040"("response to iron(II) ion")|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0018283"(iron incorporation into metallo-sulfur cluster)|go:"GO:0034986"(iron chaperone activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|interpro:IPR002908(Frataxin-like)|interpro:IPR017789(Frataxin)|interpro:IPR020895|interpro:IPR036524|rcsb pdb:2FQL|rcsb pdb:2GA5|rcsb pdb:3OEQ|rcsb pdb:3OER|rcsb pdb:4EC2|rcsb pdb:5T0V|rcsb pdb:5TRE|reactome:R-SCE-1268020|reactome:R-SCE-1362409|go:"GO:0008198"(ferrous iron binding)|sgd:YDL120W(identity)	-	-	crc64:AB1FF7478EF0E5D6	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:GZ7WP4suMiSPSAJK0TZWQMQZxzU9606	rogid:4UcroTodEXb/5+xHGpnXDXf/rd8559292	intact-crc:51B64B860FEC41EA|rigid:ygkxYyPIYj4peP+w7qkAkVu9sz0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q07732	uniprotkb:Q53EZ4	intact:EBI-33406|ensemblfungi:YDL239C|uniprotkb:D6VRB7	intact:EBI-747776|uniprotkb:Q32WF5|uniprotkb:Q3MV20|uniprotkb:Q5VY28|uniprotkb:Q6N034|ensembl:ENSP00000360540|uniprotkb:Q96H32|uniprotkb:Q9NVS7|uniprotkb:B2RDG8|intact:EBI-10173536|uniprotkb:D3DR37|intact:EBI-28973801	psi-mi:ady3_yeast(display_long)|uniprotkb:YDL239C(locus name)|uniprotkb:ADY3(gene name)|psi-mi:ADY3(display_short)	psi-mi:cep55_human(display_long)|uniprotkb:Up-regulated in colon cancer 6(gene name synonym)|uniprotkb:CEP55(gene name)|psi-mi:CEP55(display_short)|uniprotkb:URCC6(gene name synonym)|uniprotkb:C10orf3(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11546528|imex:IM-24995-2553	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010042.2|sgd:S000002398|ensemblfungi:YDL239C(gene)|ensemblfungi:YDL239C_mRNA(transcript)|go:"GO:0000001"(mitochondrion inheritance)|go:"GO:0005628"(prospore membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0030435"(sporulation resulting in formation of a cellular spore)|go:"GO:0030476"(ascospore wall assembly)|go:"GO:0032120"(ascospore-type prospore membrane formation)|go:"GO:0051301"(cell division)|go:"GO:0070056"(prospore membrane leading edge)|interpro:IPR021750|mint:Q07732|dip:DIP-1811N|sgd:YDL239C(identity)	refseq:NP_001120654.1|refseq:NP_060601.3|ensembl:ENSG00000138180(gene)|ensembl:ENST00000371485(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0014066"(regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0030496"(midbody)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042802"(identical protein binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0061952"(midbody abscission)|go:"GO:0090543"(Flemming body)|go:"GO:1904888"(cranial skeletal system development)|interpro:IPR022008|interpro:IPR038926|mint:Q53EZ4|rcsb pdb:3E1R|rcsb pdb:3WUT|rcsb pdb:3WUU|rcsb pdb:3WUV|go:"GO:0005814"(centriole)|ensembl:ENSP00000360540|dip:DIP-44581N|entrezgene/locuslink:55165(identity)	-	crc64:46F17474F30FD3D9	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Cmac2NLDdbBzVKnJfFricfeeX24559292	rogid:tuo36vVb8ZgPDR81YjZFNEg559w9606	intact-crc:8D43EB7BD3380988|rigid:6wOQ2W+NyTq4Z43Gtutq8hrUUEs	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q07379	uniprotkb:Q8TAP6	intact:EBI-2342994|uniprotkb:D6VRT9|ensemblfungi:YDL057W	intact:EBI-742887|ensembl:ENSP00000262127|uniprotkb:Q658N5|uniprotkb:Q9H9U7|uniprotkb:B0YJB2|uniprotkb:B4DXG5|uniprotkb:B4DZW1	psi-mi:yd057_yeast(display_long)|uniprotkb:YDL057W(locus name)	psi-mi:cep76_human(display_long)|uniprotkb:CEP76(gene name)|psi-mi:CEP76(display_short)|uniprotkb:C18orf9(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11546462|imex:IM-24995-2546	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002215|refseq:NP_010226.1|interpro:IPR022742|interpro:IPR029058|ensemblfungi:YDL057W(gene)|ensemblfungi:YDL057W_mRNA(transcript)|go:"GO:0016020"(membrane)|go:"GO:0016298"(lipase activity)|sgd:YDL057W(identity)	refseq:NP_079175.2|ensembl:ENSG00000101624(gene)|ensembl:ENST00000262127(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0046599"(regulation of centriole replication)|interpro:IPR028926|interpro:IPR038765|mint:Q8TAP6|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_001258918.1|entrezgene/locuslink:79959(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:U0Sf+t16Ti+vYEOEePrGjlqflhQ559292	rogid:fWzb8oIU35oVWomyDrf8u5sbxUk9606	intact-crc:053B08EE9D2559EE|rigid:aenOWHEG1ZfDrZNsCYxMcOs3fd4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q07540	uniprotkb:Q96DZ9-2	intact:EBI-2206814|uniprotkb:D6VRN0|ensemblfungi:YDL120W	intact:EBI-11522780|ensembl:ENSP00000352270|ensembl:ENSP00000497215	psi-mi:frda_yeast(display_long)|uniprotkb:YFH1(gene name)|psi-mi:YFH1(display_short)|uniprotkb:YDL120W(locus name)	psi-mi:q96dz9-2(display_long)|uniprotkb:CMTM5(gene name)|psi-mi:CMTM5(display_short)|uniprotkb:CKLFSF5(gene name synonym)|uniprotkb:Chemokine-like factor superfamily member 5(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11546519|imex:IM-24995-2552	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-7485N|refseq:NP_010163.1|sgd:S000002278|mint:Q07540|ensemblfungi:YDL120W(gene)|ensemblfungi:YDL120W_mRNA(transcript)|go:"GO:0004322"(ferroxidase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006121"(mitochondrial electron transport, succinate to ubiquinone)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0006783"(heme biosynthetic process)|go:"GO:0006811"(ion transport)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008199"(ferric iron binding)|go:"GO:0010040"("response to iron(II) ion")|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0018283"(iron incorporation into metallo-sulfur cluster)|go:"GO:0034986"(iron chaperone activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|interpro:IPR002908(Frataxin-like)|interpro:IPR017789(Frataxin)|interpro:IPR020895|interpro:IPR036524|rcsb pdb:2FQL|rcsb pdb:2GA5|rcsb pdb:3OEQ|rcsb pdb:3OER|rcsb pdb:4EC2|rcsb pdb:5T0V|rcsb pdb:5TRE|reactome:R-SCE-1268020|reactome:R-SCE-1362409|go:"GO:0008198"(ferrous iron binding)|sgd:YDL120W(identity)	ensembl:ENSG00000166091(gene)|ensembl:ENST00000359320(transcript)|ensembl:ENST00000649278(transcript)|intact:EBI-2548702(isoform-parent)|uniprotkb:Q96DZ9-2(isoform-parent)|entrezgene/locuslink:116173(identity)	-	crc64:AB1FF7478EF0E5D6	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:4UcroTodEXb/5+xHGpnXDXf/rd8559292	rogid:2TJ7rZKQNb5hH5gz9i+ujOEOIOg9606	intact-crc:B77BEF5E37E945CF|rigid:TeTvZ46aWQK4pl4xiAKjWRnNeIU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q07732	uniprotkb:Q96BR9	intact:EBI-33406|ensemblfungi:YDL239C|uniprotkb:D6VRB7	intact:EBI-742740|uniprotkb:Q8IUL5|uniprotkb:Q8IWR9|uniprotkb:Q8N2Y5|uniprotkb:Q96BX0|ensembl:ENSP00000362609	psi-mi:ady3_yeast(display_long)|uniprotkb:YDL239C(locus name)|uniprotkb:ADY3(gene name)|psi-mi:ADY3(display_short)	psi-mi:zbt8a_human(display_long)|uniprotkb:ZBTB8A(gene name)|psi-mi:ZBTB8A(display_short)|uniprotkb:BOZF1(gene name synonym)|uniprotkb:BTB/POZ and zinc-finger domain-containing factor(gene name synonym)|uniprotkb:BTB/POZ and zinc-finger domains factor on chromosome 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11546546|imex:IM-24995-2555	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010042.2|sgd:S000002398|ensemblfungi:YDL239C(gene)|ensemblfungi:YDL239C_mRNA(transcript)|go:"GO:0000001"(mitochondrion inheritance)|go:"GO:0005628"(prospore membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0030435"(sporulation resulting in formation of a cellular spore)|go:"GO:0030476"(ascospore wall assembly)|go:"GO:0032120"(ascospore-type prospore membrane formation)|go:"GO:0051301"(cell division)|go:"GO:0070056"(prospore membrane leading edge)|interpro:IPR021750|mint:Q07732|dip:DIP-1811N|sgd:YDL239C(identity)	ensembl:ENSG00000160062(gene)|ensembl:ENST00000373510(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|refseq:NP_001035531.2|refseq:NP_001278425.1|entrezgene/locuslink:653121(identity)	-	crc64:46F17474F30FD3D9	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Cmac2NLDdbBzVKnJfFricfeeX24559292	rogid:tsrPT2tHvuBryODKgRXnceXz9s09606	intact-crc:B9699B69334F3B9D|rigid:4nDxFkyXOQeI2CPShuXwWPWA6ew	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O96006	uniprotkb:Q07887	intact:EBI-740037|uniprotkb:Q96BY4|ensembl:ENSP00000370616|ensembl:ENSP00000370620|ensembl:ENSP00000370621|ensembl:ENSP00000498725	intact:EBI-33243|uniprotkb:D6VXV9|ensemblfungi:YLL049W	psi-mi:zbed1_human(display_long)|uniprotkb:ZBED1(gene name)|psi-mi:ZBED1(display_short)|uniprotkb:ALTE(gene name synonym)|uniprotkb:DREF(gene name synonym)|uniprotkb:KIAA0785(gene name synonym)|uniprotkb:TRAMP(gene name synonym)|uniprotkb:dREF homolog(gene name synonym)|uniprotkb:Putative Ac-like transposable element(gene name synonym)|uniprotkb:DNA replication-related element-binding factor(gene name synonym)|uniprotkb:Zinc finger BED domain-containing protein 1(gene name synonym)|uniprotkb:hDREF(gene name synonym)	psi-mi:ldb18_yeast(display_long)|uniprotkb:Low dye-binding protein 18(gene name synonym)|uniprotkb:LDB18(gene name)|psi-mi:LDB18(display_short)|uniprotkb:YLL049W(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11546593|imex:IM-24995-2560	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164606.1|refseq:NP_001164607.1|refseq:NP_004720.1|ensembl:ENSG00000214717(gene)|ensembl:ENST00000381218(transcript)|ensembl:ENST00000381222(transcript)|ensembl:ENST00000381223(transcript)|ensembl:ENST00000652001(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0031965"(nuclear membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044828"(negative regulation by host of viral genome replication)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0061665"(SUMO ligase activity)|go:"GO:1990466"(protein autosumoylation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003656(Zinc finger, BED-type predicted)|interpro:IPR008906(HAT dimerisation)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR036236|mint:O96006|rcsb pdb:2CT5|reactome:R-HSA-4551638|go:"GO:0005813"(centrosome)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016605"(PML body)|entrezgene/locuslink:9189(identity)	sgd:S000003972|refseq:NP_013051.1|dip:DIP-1932N|ensemblfungi:YLL049W(gene)|ensemblfungi:YLL049W_mRNA(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0005869"(dynactin complex)|sgd:YLL049W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:jl97ZV2Kz5YAmQKktWt/wk7OkRw9606	rogid:oTvD3VEb0ZAfYezSviDPi8wVGxg559292	intact-crc:0A2B90629520DDCA|rigid:LMPnmhfxp/6331BqlNLbAhctQcA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q07821	uniprotkb:Q13137	intact:EBI-27136|uniprotkb:D6VXX7|ensemblfungi:YLL027W	intact:EBI-739580|uniprotkb:B4DDC4|uniprotkb:E7ENK0|uniprotkb:Q53FQ5|uniprotkb:Q53HB5|uniprotkb:Q6IBN9|uniprotkb:Q9BTF7|uniprotkb:B2RBT0|ensembl:ENSP00000258947|uniprotkb:B4E0C0|uniprotkb:E7ETP5|uniprotkb:B4DDT4|uniprotkb:B4DP36|uniprotkb:E9PBE5	psi-mi:isa1_yeast(display_long)|uniprotkb:YLL027W(locus name)|uniprotkb:ISA1(gene name)|psi-mi:ISA1(display_short)	psi-mi:caco2_human(display_long)|uniprotkb:CALCOCO2(gene name)|psi-mi:CALCOCO2(display_short)|uniprotkb:NDP52(gene name synonym)|uniprotkb:Nuclear domain 10 protein NDP52(gene name synonym)|uniprotkb:Antigen nuclear dot 52 kDa protein(gene name synonym)|uniprotkb:Nuclear dot protein 52(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11546584|imex:IM-24995-2559	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013073.1|sgd:S000003950|mint:Q07821|dip:DIP-1394N|ensemblfungi:YLL027W(gene)|ensemblfungi:YLL027W_mRNA(transcript)|go:"GO:0005506"(iron ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0009102"(biotin biosynthetic process)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0051536"(iron-sulfur cluster binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|go:"GO:0106035"(protein maturation by [4Fe-4S] cluster transfer)|interpro:IPR000361(HesB/YadR/YfhF-like)|interpro:IPR016092(HesB/YadR/YfhF)|interpro:IPR017870|interpro:IPR035903|reactome:R-SCE-1362409|sgd:YLL027W(identity)	refseq:NP_001248319.1|refseq:NP_001248320.1|refseq:NP_001248322.1|refseq:NP_005822.1|ensembl:ENSG00000136436(gene)|ensembl:ENST00000258947(transcript)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016032"(viral process)|go:"GO:0016605"(PML body)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0098792"(xenophagy)|go:"GO:1901098"(positive regulation of autophagosome maturation)|interpro:IPR041611|interpro:IPR041641|mint:Q13137|rcsb pdb:2MXP|rcsb pdb:3VVV|rcsb pdb:3VVW|rcsb pdb:4GXL|rcsb pdb:4HAN|rcsb pdb:4XKL|rcsb pdb:5AAQ|rcsb pdb:5Z7A|rcsb pdb:5Z7L|refseq:NP_001248324.1|dip:DIP-57534N|entrezgene/locuslink:10241(identity)	-	crc64:226C286B4F80DE6D	crc64:609B121DA1A9DCB8	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:QD74jkP7pZD875xxXj5J2YPKb5g559292	rogid:N/GPJUGBK+Dh5Cg+csmafphuo9M9606	intact-crc:451B1FE16C1E9808|rigid:/QlFAJZFEm1z8taqFaGOjmznxy4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q07732	uniprotkb:Q9Y2J4	intact:EBI-33406|ensemblfungi:YDL239C|uniprotkb:D6VRB7	intact:EBI-746752|intact:EBI-28986657|ensembl:ENSP00000409999|uniprotkb:Q53EP1|uniprotkb:Q96F99|uniprotkb:Q9UKB4|uniprotkb:A8K6F1|uniprotkb:B7Z5Q1|uniprotkb:E9PHW3	psi-mi:ady3_yeast(display_long)|uniprotkb:YDL239C(locus name)|uniprotkb:ADY3(gene name)|psi-mi:ADY3(display_short)	psi-mi:amol2_human(display_long)|uniprotkb:Leman coiled-coil protein(gene name synonym)|uniprotkb:AMOTL2(gene name)|psi-mi:AMOTL2(display_short)|uniprotkb:KIAA0989(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11546573|imex:IM-24995-2558	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010042.2|sgd:S000002398|ensemblfungi:YDL239C(gene)|ensemblfungi:YDL239C_mRNA(transcript)|go:"GO:0000001"(mitochondrion inheritance)|go:"GO:0005628"(prospore membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0030435"(sporulation resulting in formation of a cellular spore)|go:"GO:0030476"(ascospore wall assembly)|go:"GO:0032120"(ascospore-type prospore membrane formation)|go:"GO:0051301"(cell division)|go:"GO:0070056"(prospore membrane leading edge)|interpro:IPR021750|mint:Q07732|dip:DIP-1811N|sgd:YDL239C(identity)	refseq:NP_001265612.1|refseq:NP_001265614.1|ensembl:ENSG00000114019(gene)|refseq:XP_006713717.1|refseq:NP_057285.3|refseq:XP_011511183.1|ensembl:ENST00000422605(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0003365"(establishment of cell polarity involved in ameboidal cell migration)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0035329"(hippo signaling)|go:"GO:0055037"(recycling endosome)|interpro:IPR009114(Angiomotin)|interpro:IPR024646|mint:Q9Y2J4|reactome:R-HSA-2028269|refseq:XP_016862069.1|refseq:XP_016862070.1|refseq:XP_016862071.1|ensembl:ENST00000249883|ensembl:ENSP00000249883|ensembl:ENSP00000409999|ensembl:ENST00000513145|ensembl:ENSP00000425475|ensembl:ENST00000514516|ensembl:ENSP00000424765|dip:DIP-57510N|entrezgene/locuslink:51421(identity)	-	crc64:46F17474F30FD3D9	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Cmac2NLDdbBzVKnJfFricfeeX24559292	rogid:SHtKAcLLnTpSSLwVE7yQ1WECoZk9606	intact-crc:AC8061F056AC7C21|rigid:O4SyFP0fLm1NYk8An6KJOIssr18	false	-	sufficient binding region:314-779	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q07732	uniprotkb:Q96IK5	intact:EBI-33406|ensemblfungi:YDL239C|uniprotkb:D6VRB7	intact:EBI-2548508|ensembl:ENSP00000282570|uniprotkb:Q9H826|uniprotkb:Q9H8V7|uniprotkb:Q9H927	psi-mi:ady3_yeast(display_long)|uniprotkb:YDL239C(locus name)|uniprotkb:ADY3(gene name)|psi-mi:ADY3(display_short)	psi-mi:gmcl1_human(display_long)|uniprotkb:GMCL1(gene name)|psi-mi:GMCL1(display_short)|uniprotkb:GCL(gene name synonym)|uniprotkb:BTBD13(gene name synonym)|uniprotkb:SPATA29(gene name synonym)|uniprotkb:Spermatogenesis-associated protein 29(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11546564|imex:IM-24995-2557	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010042.2|sgd:S000002398|ensemblfungi:YDL239C(gene)|ensemblfungi:YDL239C_mRNA(transcript)|go:"GO:0000001"(mitochondrion inheritance)|go:"GO:0005628"(prospore membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0030435"(sporulation resulting in formation of a cellular spore)|go:"GO:0030476"(ascospore wall assembly)|go:"GO:0032120"(ascospore-type prospore membrane formation)|go:"GO:0051301"(cell division)|go:"GO:0070056"(prospore membrane leading edge)|interpro:IPR021750|mint:Q07732|dip:DIP-1811N|sgd:YDL239C(identity)	ensembl:ENSG00000087338(gene)|ensembl:ENST00000282570(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0007281"(germ cell development)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016363"(nuclear matrix)|go:"GO:0042802"(identical protein binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR043380|refseq:NP_848526.1|entrezgene/locuslink:64395(identity)	-	crc64:46F17474F30FD3D9	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Cmac2NLDdbBzVKnJfFricfeeX24559292	rogid:ED8yqySVu7BWxpw3DUSNBZSQWrk9606	intact-crc:1A224F4D392CE7D4|rigid:tPzkqD4O/YtqXvlondCuqaUq5Yk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q07732	uniprotkb:Q96CN9	intact:EBI-33406|ensemblfungi:YDL239C|uniprotkb:D6VRB7	intact:EBI-746252|uniprotkb:Q9H6N7|ensembl:ENSP00000318821	psi-mi:ady3_yeast(display_long)|uniprotkb:YDL239C(locus name)|uniprotkb:ADY3(gene name)|psi-mi:ADY3(display_short)	psi-mi:gcc1_human(display_long)|uniprotkb:Golgi coiled-coil protein 1(gene name synonym)|uniprotkb:GCC1(gene name)|psi-mi:GCC1(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11546555|imex:IM-24995-2556	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010042.2|sgd:S000002398|ensemblfungi:YDL239C(gene)|ensemblfungi:YDL239C_mRNA(transcript)|go:"GO:0000001"(mitochondrion inheritance)|go:"GO:0005628"(prospore membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0030435"(sporulation resulting in formation of a cellular spore)|go:"GO:0030476"(ascospore wall assembly)|go:"GO:0032120"(ascospore-type prospore membrane formation)|go:"GO:0051301"(cell division)|go:"GO:0070056"(prospore membrane leading edge)|interpro:IPR021750|mint:Q07732|dip:DIP-1811N|sgd:YDL239C(identity)	refseq:NP_078799.2|ensembl:ENSG00000179562(gene)|ensembl:ENST00000321407(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0031267"(small GTPase binding)|interpro:IPR000237(GRIP)|reactome:R-HSA-6811440|go:"GO:0000138"(Golgi trans cisterna)|entrezgene/locuslink:79571(identity)	-	crc64:46F17474F30FD3D9	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Cmac2NLDdbBzVKnJfFricfeeX24559292	rogid:SCI+peKjPIvl/HbUUpHGM++qiRE9606	intact-crc:806E8B01D99AFADA|rigid:08Jt5ox7qz3ClHaE+1psuSQMvA0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q07732	uniprotkb:Q8NA61-2	intact:EBI-33406|ensemblfungi:YDL239C|uniprotkb:D6VRB7	intact:EBI-11524851|ensembl:ENSP00000368249|ensembl:ENSP00000480148	psi-mi:ady3_yeast(display_long)|uniprotkb:YDL239C(locus name)|uniprotkb:ADY3(gene name)|psi-mi:ADY3(display_short)	psi-mi:q8na61-2(display_long)|uniprotkb:CBY2(gene name)|psi-mi:CBY2(display_short)|uniprotkb:SPERT(gene name synonym)|uniprotkb:Spermatid-associated protein(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11546537|imex:IM-24995-2554	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010042.2|sgd:S000002398|ensemblfungi:YDL239C(gene)|ensemblfungi:YDL239C_mRNA(transcript)|go:"GO:0000001"(mitochondrion inheritance)|go:"GO:0005628"(prospore membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0030435"(sporulation resulting in formation of a cellular spore)|go:"GO:0030476"(ascospore wall assembly)|go:"GO:0032120"(ascospore-type prospore membrane formation)|go:"GO:0051301"(cell division)|go:"GO:0070056"(prospore membrane leading edge)|interpro:IPR021750|mint:Q07732|dip:DIP-1811N|sgd:YDL239C(identity)	intact:EBI-741724(isoform-parent)|ensembl:ENSG00000174015(gene)|ensembl:ENST00000378966(transcript)|ensembl:ENST00000610924(transcript)|uniprotkb:Q8NA61-2(isoform-parent)|entrezgene/locuslink:220082(identity)	-	crc64:46F17474F30FD3D9	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Cmac2NLDdbBzVKnJfFricfeeX24559292	rogid:SogYcXGGMYRYzB9xKC5o0pEtsDs9606	intact-crc:A83D7180B12F2B38|rigid:jaZwkCeZ60vDm4aVh1qzmjV6mYk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8NEC5	uniprotkb:Q07986	intact:EBI-744545|uniprotkb:Q96P76|ensembl:ENSP00000309052	intact:EBI-37985|uniprotkb:D6VY39|ensemblfungi:YLR036C	psi-mi:ctsr1_human(display_long)|uniprotkb:CATSPER1(gene name)|psi-mi:CATSPER1(display_short)	psi-mi:yl036_yeast(display_long)|uniprotkb:YLR036C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11546651|imex:IM-24995-2566	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_444282.3|ensembl:ENSG00000175294(gene)|ensembl:ENST00000312106(transcript)|go:"GO:0005227"(calcium activated cation channel activity)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007283"(spermatogenesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0031514"(motile cilium)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0036128"(CatSper complex)|go:"GO:0060296"(regulation of cilium beat frequency involved in ciliary motility)|interpro:IPR005821(Ion transport)|interpro:IPR027359|interpro:IPR028746|reactome:R-HSA-1300642|entrezgene/locuslink:117144(identity)	sgd:S000004026|refseq:NP_013137.1|dip:DIP-2127N|ensemblfungi:YLR036C(gene)|ensemblfungi:YLR036C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0016021"(integral component of membrane)|interpro:IPR031427|sgd:YLR036C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:hY8kq7xGiDrD6FydKByugAo0t+U9606	rogid:GGcRlz7wYc6R9SI/NTywlmxOu8Q559292	intact-crc:E031D80054B79496|rigid:J0wMoMK8ttPT5GRI+vP3FHWpcTs	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q07978	uniprotkb:Q8WWB3	intact:EBI-38683|uniprotkb:D6VY33|ensemblfungi:YLR031W	intact:EBI-740680|ensembl:ENSP00000361276|ensembl:ENSP00000361278|ensembl:ENSP00000402890|uniprotkb:Q5QP03|uniprotkb:Q5QP04|uniprotkb:Q6WNP4|uniprotkb:Q6ZU87|uniprotkb:A8K927	psi-mi:yl031_yeast(display_long)|uniprotkb:YLR031W(locus name)	psi-mi:dydc1_human(display_long)|uniprotkb:DYDC1(gene name)|psi-mi:DYDC1(display_short)|uniprotkb:DPY30D1(gene name synonym)|uniprotkb:RSD9(orf name)|uniprotkb:RSD-9(orf name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11546642|imex:IM-24995-2565	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000004021|refseq:NP_013131.1|dip:DIP-4435N|ensemblfungi:YLR031W(gene)|ensemblfungi:YLR031W_mRNA(transcript)|sgd:YLR031W(identity)	refseq:NP_620167.1|ensembl:ENSG00000170788(gene)|ensembl:ENST00000372202(transcript)|ensembl:ENST00000372204(transcript)|ensembl:ENST00000421924(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0006348"|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|interpro:IPR007858(Dpy-30)|interpro:IPR037856|refseq:XP_011537636.1|refseq:XP_011537637.1|refseq:NP_001255982.1|refseq:XP_005269606.1|refseq:XP_005269607.1|entrezgene/locuslink:143241(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:T3r2tgTMVd+abiwf7/Ccb/QJ2ZQ559292	rogid:W6GUazYFXZGHGijUBpAJ5GiRuXA9606	intact-crc:612F79C871D68D82|rigid:L6aPc/q8SYVlXcsNAWhyn+g24+U	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q07978	uniprotkb:Q15311	intact:EBI-38683|uniprotkb:D6VY33|ensemblfungi:YLR031W	intact:EBI-749285|uniprotkb:D3DUI0|ensembl:ENSP00000019317|ensembl:ENSP00000372924	psi-mi:yl031_yeast(display_long)|uniprotkb:YLR031W(locus name)	psi-mi:rbp1_human(display_long)|uniprotkb:Ral-interacting protein 1(gene name synonym)|uniprotkb:76 kDa Ral-interacting protein(gene name synonym)|uniprotkb:Dinitrophenyl S-glutathione ATPase(gene name synonym)|uniprotkb:RALBP1(gene name)|psi-mi:RALBP1(display_short)|uniprotkb:RLIP1(gene name synonym)|uniprotkb:RLIP76(gene name synonym)|uniprotkb:RLIP(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11546633|imex:IM-24995-2564	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000004021|refseq:NP_013131.1|dip:DIP-4435N|ensemblfungi:YLR031W(gene)|ensemblfungi:YLR031W_mRNA(transcript)|sgd:YLR031W(identity)	refseq:NP_006779.1|ensembl:ENSG00000017797(gene)|ensembl:ENST00000019317(transcript)|ensembl:ENST00000383432(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0006935"(chemotaxis)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008559"(ABC-type xenobiotic transporter activity)|go:"GO:0015431"(ABC-type glutathione S-conjugate transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032489"(regulation of Cdc42 protein signal transduction)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0055085"(transmembrane transport)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:1900753"(doxorubicin transport)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR000198(RhoGAP)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR039767|mint:Q15311|rcsb pdb:2KWH|rcsb pdb:2KWI|rcsb pdb:2MBG|rcsb pdb:6ZQT|rcsb pdb:6ZRN|reactome:R-HSA-9013148|reactome:R-HSA-9013149|entrezgene/locuslink:10928(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:T3r2tgTMVd+abiwf7/Ccb/QJ2ZQ559292	rogid:6u1yy+UdGWJbJ9SiItSAp+CqeVk9606	intact-crc:16AE9C10C546B408|rigid:0n9EzCn+UfVIyeu8uLmWUuWgaZ4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q07978	uniprotkb:G5E962	intact:EBI-38683|uniprotkb:D6VY33|ensemblfungi:YLR031W	intact:EBI-11525615|ensembl:ENSP00000328177	psi-mi:yl031_yeast(display_long)|uniprotkb:YLR031W(locus name)	psi-mi:g5e962_human(display_long)|uniprotkb:hCG_1644200(orf name)|uniprotkb:MAGEA11(gene name)|psi-mi:MAGEA11(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11546622|imex:IM-24995-2563	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000004021|refseq:NP_013131.1|dip:DIP-4435N|ensemblfungi:YLR031W(gene)|ensemblfungi:YLR031W_mRNA(transcript)|sgd:YLR031W(identity)	refseq:NP_001011544.1|ensembl:ENSG00000185247(gene)|ensembl:ENST00000333104(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016604"(nuclear body)|interpro:IPR002190(MAGE protein)|interpro:IPR021072|interpro:IPR030099|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|entrezgene/locuslink:4110(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:T3r2tgTMVd+abiwf7/Ccb/QJ2ZQ559292	rogid:sVB0aA6yibWUx/d2SE+pwpKKgtI9606	intact-crc:F233E6D2C54597CA|rigid:9pXV7NJ/j3aIqFAFo5bgeW9LAzI	false	-	sufficient binding region:82-400	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q0VDD7	uniprotkb:Q07951	intact:EBI-741210|ensembl:ENSP00000465822|ensembl:ENSP00000500215|uniprotkb:Q13411|uniprotkb:Q8N825|uniprotkb:Q96D63|uniprotkb:Q9BU49	intact:EBI-31959|uniprotkb:D6VY23|ensemblfungi:YLR021W	psi-mi:brme1_human(display_long)|uniprotkb:BRME1(gene name)|psi-mi:BRME1(display_short)|uniprotkb:C19orf57(gene name synonym)|uniprotkb:Pre-T/NK cell-associated protein 3B3(gene name synonym)	psi-mi:poc3_yeast(display_long)|uniprotkb:POC3(gene name synonym)|uniprotkb:Increased recombination centers protein 25(gene name synonym)|uniprotkb:IRC25(gene name)|psi-mi:IRC25(display_short)|uniprotkb:DMP2(gene name synonym)|uniprotkb:YLR021W(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11546611|imex:IM-24995-2562	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_077299.3|ensembl:ENSG00000132016(gene)|ensembl:ENSG00000288152(gene)|ensembl:ENST00000586783(transcript)|ensembl:ENST00000672170(transcript)|go:"GO:0005694"(chromosome)|go:"GO:0007144"(female meiosis I)|go:"GO:0007275"(multicellular organism development)|go:"GO:0007283"(spermatogenesis)|go:"GO:1990918"(double-strand break repair involved in meiotic recombination)|interpro:IPR031441|refseq:NP_001332773.1|entrezgene/locuslink:79173(identity)	refseq:NP_013121.1|sgd:S000004011|dip:DIP-4747N|mint:Q07951|ensemblfungi:YLR021W(gene)|ensemblfungi:YLR021W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043248"(proteasome assembly)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|interpro:IPR018854|rcsb pdb:2Z5B|rcsb pdb:2Z5C|sgd:YLR021W(identity)	-	-	crc64:6CA25E8ED0491EE2	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:YUbAjs5ZmWOPWRA9kq5qRZRioR49606	rogid:5xcWnXqOt0DxQvelDvtc8ob2bj0559292	intact-crc:0768960A4E35A7C2|rigid:35A6MX4dE+GvyRN0fhmWQM9BMAo	false	sufficient binding region:336-668	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q08144	uniprotkb:Q12846	intact:EBI-19302|uniprotkb:D6W248|uniprotkb:E9P933|ensemblfungi:YOL018C	intact:EBI-744942|uniprotkb:Q15525|ensembl:ENSP00000317714|uniprotkb:Q6FHE8|uniprotkb:A8MXY0	psi-mi:tlg2_yeast(display_long)|uniprotkb:YOL018C(locus name)|uniprotkb:TLG2(gene name)|psi-mi:TLG2(display_short)|uniprotkb:Syntaxin TLG2(gene name synonym)	psi-mi:stx4_human(display_long)|uniprotkb:Renal carcinoma antigen NY-REN-31(gene name synonym)|uniprotkb:STX4(gene name)|psi-mi:STX4(display_short)|uniprotkb:STX4A(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11546660|imex:IM-24995-2567	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014624.1|sgd:S000005378|ensemblfungi:YOL018C(gene)|ensemblfungi:YOL018C_mRNA(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006673"(inositol phosphoceramide metabolic process)|go:"GO:0006675"(mannosyl-inositol phosphorylceramide metabolic process)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0031303"(integral component of endosome membrane)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0032527"(protein exit from endoplasmic reticulum)|go:"GO:0048278"(vesicle docking)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|interpro:IPR028673|reactome:R-SCE-6811440|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0006897"(endocytosis)|go:"GO:0006906"(vesicle fusion)|go:"GO:0009306"(protein secretion)|dip:DIP-4244N|mint:Q08144|sgd:YOL018C(identity)	ensembl:ENSG00000103496(gene)|refseq:NP_004595.2|ensembl:ENST00000313843(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0000322"(storage vacuole)|go:"GO:0002639"(positive regulation of immunoglobulin production)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005768"(endosome)|go:"GO:0005773"(vacuole)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006887"(exocytosis)|go:"GO:0006906"(vesicle fusion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016230"(sphingomyelin phosphodiesterase activator activity)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0032589"(neuron projection membrane)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035493"(SNARE complex assembly)|go:"GO:0035749"(myelin sheath adaxonal region)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0036477"(somatodendritic compartment)|go:"GO:0042581"(specific granule)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043197"(dendritic spine)|go:"GO:0043219"(lateral loop)|go:"GO:0043311"(positive regulation of eosinophil degranulation)|go:"GO:0045202"(synapse)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0048278"(vesicle docking)|go:"GO:0048284"(organelle fusion)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048787"(presynaptic active zone membrane)|go:"GO:0050921"(positive regulation of chemotaxis)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1902041"(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1903575"(cornified envelope assembly)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|reactome:R-HSA-114516|reactome:R-HSA-1236974|reactome:R-HSA-1445148|reactome:R-HSA-199992|reactome:R-HSA-449836|interpro:IPR006011(Syntaxin, N-terminal)|refseq:NP_001259025.1|entrezgene/locuslink:6810(identity)	-	crc64:CEBD6FE11278B1F0	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:M7Ezt/D1lvPf/T8TrjQwtKNhFhw559292	rogid:NvOLGIGe/XO2aDPSpdPzrtKniZY9606	intact-crc:582D777D2ED7958C|rigid:Z47hgCTIBXp+/pzO7xUoEJ74PoY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q07951	uniprotkb:Q8N5R6	intact:EBI-31959|uniprotkb:D6VY23|ensemblfungi:YLR021W	intact:EBI-740841|intact:EBI-953781|uniprotkb:B3KQ49|uniprotkb:A8K3U4|uniprotkb:A8MPQ6|uniprotkb:A8MV61|uniprotkb:A8MVU9|uniprotkb:Q9H5Q6|uniprotkb:Q8TAX6|intact:EBI-2320546|intact:EBI-11522976	psi-mi:poc3_yeast(display_long)|uniprotkb:POC3(gene name synonym)|uniprotkb:Increased recombination centers protein 25(gene name synonym)|uniprotkb:IRC25(gene name)|psi-mi:IRC25(display_short)|uniprotkb:DMP2(gene name synonym)|uniprotkb:YLR021W(locus name)	psi-mi:ccd33_human(display_long)|uniprotkb:CCDC33(gene name)|psi-mi:CCDC33(display_short)|uniprotkb:Cancer/testis antigen 61(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11546602|imex:IM-24995-2561	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013121.1|sgd:S000004011|dip:DIP-4747N|mint:Q07951|ensemblfungi:YLR021W(gene)|ensemblfungi:YLR021W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043248"(proteasome assembly)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|interpro:IPR018854|rcsb pdb:2Z5B|rcsb pdb:2Z5C|sgd:YLR021W(identity)	refseq:NP_079331.3|interpro:IPR000008(C2 calcium-dependent membrane targeting)|go:"GO:0005777"(peroxisome)|refseq:NP_001274110.1|refseq:NP_877592.2|mint:Q8N5R6|interpro:IPR035892|interpro:IPR039889|entrezgene/locuslink:80125(identity)	-	crc64:6CA25E8ED0491EE2	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2021/11/30	rogid:5xcWnXqOt0DxQvelDvtc8ob2bj0559292	rogid:eEIn7pQyfdHWx8TeLJpYy0i/gww9606	intact-crc:36E03A357CA2E966|rigid:k/XPBxFV+++TO+0BhS/Z4sYVhQQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q08204	uniprotkb:Q9UKS7-2	intact:EBI-34125|uniprotkb:D6W231|ensemblfungi:YOL034W	intact:EBI-11536241|ensembl:ENSP00000363439	psi-mi:smc5_yeast(display_long)|uniprotkb:SMC5(gene name)|psi-mi:SMC5(display_short)|uniprotkb:YOL034W(locus name)	psi-mi:q9uks7-2(display_long)|uniprotkb:HELIOS(gene name synonym)|uniprotkb:Ikaros family zinc finger protein 2(gene name synonym)|uniprotkb:ZNFN1A2(gene name synonym)|uniprotkb:Helios 1v(isoform synonym)|uniprotkb:IKZF2(gene name)|psi-mi:IKZF2(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11546696|imex:IM-24995-2571	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014608.1|sgd:S000005394|mint:Q08204|dip:DIP-1979N|ensemblfungi:YOL034W(gene)|ensemblfungi:YOL034W_mRNA(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000725"(recombinational repair)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006281"(DNA repair)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0016925"(protein sumoylation)|go:"GO:0030915"(Smc5-Smc6 complex)|go:"GO:0051304"(chromosome separation)|go:"GO:0071139"(resolution of recombination intermediates)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR027131|interpro:IPR027417|rcsb pdb:3HTK|reactome:R-SCE-3108214|sgd:YOL034W(identity)	intact:EBI-3893057(isoform-parent)|ensembl:ENSG00000030419(gene)|ensembl:ENST00000374319(transcript)|uniprotkb:Q9UKS7-2(isoform-parent)|entrezgene/locuslink:22807(identity)	-	crc64:6752B96438CFB549	isoform-comment:"Contains a glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) at position 95."	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:7EBoBNiTfotgfzhZ2+a+PcQTAqc559292	rogid:BPYW+3VwNBn9+7Qbh63ii8np0F09606	intact-crc:91D6B32C51606B5F|rigid:BcCyHJrysULnVjzARp46XnwdqmM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q08204	uniprotkb:Q5JR59-3	intact:EBI-34125|uniprotkb:D6W231|ensemblfungi:YOL034W	intact:EBI-11522433|ensembl:ENSP00000370186	psi-mi:smc5_yeast(display_long)|uniprotkb:SMC5(gene name)|psi-mi:SMC5(display_short)|uniprotkb:YOL034W(locus name)	psi-mi:q5jr59-3(display_long)|uniprotkb:MTUS2(gene name)|psi-mi:MTUS2(display_short)|uniprotkb:CAZIP(gene name synonym)|uniprotkb:Cardiac zipper protein(gene name synonym)|uniprotkb:KIAA0774(gene name synonym)|uniprotkb:Microtubule plus-end tracking protein TIP150(gene name synonym)|uniprotkb:TIP150(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11546687|imex:IM-24995-2570	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014608.1|sgd:S000005394|mint:Q08204|dip:DIP-1979N|ensemblfungi:YOL034W(gene)|ensemblfungi:YOL034W_mRNA(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000725"(recombinational repair)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006281"(DNA repair)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0016925"(protein sumoylation)|go:"GO:0030915"(Smc5-Smc6 complex)|go:"GO:0051304"(chromosome separation)|go:"GO:0071139"(resolution of recombination intermediates)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR027131|interpro:IPR027417|rcsb pdb:3HTK|reactome:R-SCE-3108214|sgd:YOL034W(identity)	ensembl:ENSG00000132938(gene)|ensembl:ENST00000380808(transcript)|intact:EBI-742948(isoform-parent)|uniprotkb:Q5JR59-3(isoform-parent)|entrezgene/locuslink:23281(identity)	-	crc64:6752B96438CFB549	isoform-comment:No experimental confirmation available.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:7EBoBNiTfotgfzhZ2+a+PcQTAqc559292	rogid:npId9tC7VoLN/jteoBiRbSYChPs9606	intact-crc:DEBC5BFECEFC3D1F|rigid:5FCJttU5dvY+BGiAtowtRs3KLuQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q08144	uniprotkb:Q969F0	intact:EBI-19302|uniprotkb:D6W248|uniprotkb:E9P933|ensemblfungi:YOL018C	intact:EBI-743099|ensembl:ENSP00000359375	psi-mi:tlg2_yeast(display_long)|uniprotkb:YOL018C(locus name)|uniprotkb:TLG2(gene name)|psi-mi:TLG2(display_short)|uniprotkb:Syntaxin TLG2(gene name synonym)	psi-mi:fate1_human(display_long)|uniprotkb:Tumor antigen BJ-HCC-2(gene name synonym)|uniprotkb:Cancer/testis antigen 43(gene name synonym)|uniprotkb:FATE1(gene name)|psi-mi:FATE1(display_short)|uniprotkb:FATE(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11546678|imex:IM-24995-2569	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014624.1|sgd:S000005378|ensemblfungi:YOL018C(gene)|ensemblfungi:YOL018C_mRNA(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006673"(inositol phosphoceramide metabolic process)|go:"GO:0006675"(mannosyl-inositol phosphorylceramide metabolic process)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0031303"(integral component of endosome membrane)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0032527"(protein exit from endoplasmic reticulum)|go:"GO:0048278"(vesicle docking)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|interpro:IPR028673|reactome:R-SCE-6811440|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0006897"(endocytosis)|go:"GO:0006906"(vesicle fusion)|go:"GO:0009306"(protein secretion)|dip:DIP-4244N|mint:Q08144|sgd:YOL018C(identity)	refseq:NP_149076.1|ensembl:ENSG00000147378(gene)|ensembl:ENST00000370350(transcript)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|go:"GO:0051562"(negative regulation of mitochondrial calcium ion concentration)|interpro:IPR039153|interpro:IPR039433|mint:Q969F0|entrezgene/locuslink:89885(identity)	-	crc64:CEBD6FE11278B1F0	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:M7Ezt/D1lvPf/T8TrjQwtKNhFhw559292	rogid:Nm1N6lO92MHr5rIKC007oouF5RE9606	intact-crc:002153D868637957|rigid:cQACnOQCbuaL/pzJ2LBnjJi+ikM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q08144	uniprotkb:Q8N6L0	intact:EBI-19302|uniprotkb:D6W248|uniprotkb:E9P933|ensemblfungi:YOL018C	intact:EBI-749265|uniprotkb:Q96MC3|ensembl:ENSP00000404220	psi-mi:tlg2_yeast(display_long)|uniprotkb:YOL018C(locus name)|uniprotkb:TLG2(gene name)|psi-mi:TLG2(display_short)|uniprotkb:Syntaxin TLG2(gene name synonym)	psi-mi:kash5_human(display_long)|uniprotkb:KASH5(gene name)|psi-mi:KASH5(display_short)|uniprotkb:CCDC155(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 155(gene name synonym)|uniprotkb:KASH domain-containing protein 5(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11546669|imex:IM-24995-2568	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014624.1|sgd:S000005378|ensemblfungi:YOL018C(gene)|ensemblfungi:YOL018C_mRNA(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006673"(inositol phosphoceramide metabolic process)|go:"GO:0006675"(mannosyl-inositol phosphorylceramide metabolic process)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0031303"(integral component of endosome membrane)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0032527"(protein exit from endoplasmic reticulum)|go:"GO:0048278"(vesicle docking)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|interpro:IPR028673|reactome:R-SCE-6811440|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0006897"(endocytosis)|go:"GO:0006906"(vesicle fusion)|go:"GO:0009306"(protein secretion)|dip:DIP-4244N|mint:Q08144|sgd:YOL018C(identity)	refseq:NP_653289.3|ensembl:ENSG00000161609(gene)|ensembl:ENST00000447857(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034397"(telomere localization)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051225"(spindle assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0090172"(microtubule cytoskeleton organization involved in homologous chromosome segregation)|go:"GO:0090220"(chromosome localization to nuclear envelope involved in homologous chromosome segregation)|go:"GO:0090619"(meiotic spindle pole)|interpro:IPR011992(EF-Hand type)|interpro:IPR028168|interpro:IPR028170|interpro:IPR039508|mint:Q8N6L0|rcsb pdb:6R2I|rcsb pdb:6WMF|entrezgene/locuslink:147872(identity)	-	crc64:CEBD6FE11278B1F0	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:M7Ezt/D1lvPf/T8TrjQwtKNhFhw559292	rogid:Wl9L7AcvDHCZuKjYLn8QgGIbZTc9606	intact-crc:5C904CC17FE9176E|rigid:7rwn6m3XKT9W7TGcSkZG80H+Vtc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q08273	uniprotkb:Q13620	intact:EBI-31686|uniprotkb:D6W1T5|ensemblfungi:YOL133W	intact:EBI-456067|uniprotkb:Q6PIE4|uniprotkb:Q6UP07|uniprotkb:B3KVX4|uniprotkb:B7Z5K8|uniprotkb:Q7Z673|uniprotkb:Q9BY37|uniprotkb:Q9UEB7|uniprotkb:Q9UED7|uniprotkb:B1APK5|ensembl:ENSP00000505084|ensembl:ENSP00000505176|ensembl:ENSP00000506259	psi-mi:rbx1_yeast(display_long)|uniprotkb:E3 ubiquitin-protein ligase complex SCF subunit HRT1(gene name synonym)|uniprotkb:High level expression reduces Ty3 transposition protein 1(gene name synonym)|uniprotkb:HRT1(gene name)|psi-mi:HRT1(display_short)|uniprotkb:RBX1(gene name synonym)|uniprotkb:ROC1(gene name synonym)|uniprotkb:Regulator of cullins protein 1(gene name synonym)|uniprotkb:YOL133W(locus name)	psi-mi:cul4b_human(display_long)|uniprotkb:CUL4B(gene name)|psi-mi:CUL4B(display_short)|uniprotkb:KIAA0695(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11546741|imex:IM-24995-2576	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014508.1|sgd:S000005493|dip:DIP-1373N|mint:Q08273|ensemblfungi:YOL133W(gene)|ensemblfungi:YOL133W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0035361"(Cul8-RING ubiquitin ligase complex)|go:"GO:0051301"(cell division)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097602"(cullin family protein binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR024766|reactome:R-SCE-5696395|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-68949|reactome:R-SCE-8854050|reactome:R-SCE-8951664|reactome:R-SCE-983168|sgd:YOL133W(identity)	refseq:NP_001073341.1|refseq:NP_003579.3|ensembl:ENST00000371322|ensembl:ENSP00000360373|ensembl:ENST00000371323|ensembl:ENSP00000360374|ensembl:ENSP00000505084|ensembl:ENSP00000506259|ensembl:ENSP00000505176|refseq:XP_011529702.1|dip:DIP-31609N|ensembl:ENSG00000158290(gene)|ensembl:ENST00000680673(transcript)|ensembl:ENST00000681253(transcript)|ensembl:ENST00000681652(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031175"(neuron projection development)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031465"(Cul4B-RING E3 ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070914"(UV-damage excision repair)|reactome:R-HSA-5696394|reactome:R-HSA-5696395|reactome:R-HSA-5696400|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-8951664|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR033044|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|mint:Q13620|rcsb pdb:2DO7|rcsb pdb:4A0C|rcsb pdb:4A0L|rcsb pdb:4A64|reactome:R-HSA-110314|entrezgene/locuslink:8450(identity)	-	crc64:A9C3193E48CAF881	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:7LBUfvb6zpWuPkbMDrEAnrMuJj8559292	rogid:D75aMBt3GaBdpBt5Mxsxk7yiRVg9606	intact-crc:45BFA9AD3B21FB1A|rigid:Vra33FHy1ONLghMcrhOtZAGNVTo	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O95198	uniprotkb:Q08273	intact:EBI-746999|uniprotkb:B2RD18|uniprotkb:Q8N484|uniprotkb:Q8TBH5|uniprotkb:A6NCM7|uniprotkb:B4DFH7|uniprotkb:F5H6M3|ensembl:ENSP00000226725	intact:EBI-31686|uniprotkb:D6W1T5|ensemblfungi:YOL133W	psi-mi:klhl2_human(display_long)|uniprotkb:Actin-binding protein Mayven(gene name synonym)|uniprotkb:KLHL2(gene name)|psi-mi:KLHL2(display_short)	psi-mi:rbx1_yeast(display_long)|uniprotkb:E3 ubiquitin-protein ligase complex SCF subunit HRT1(gene name synonym)|uniprotkb:High level expression reduces Ty3 transposition protein 1(gene name synonym)|uniprotkb:HRT1(gene name)|psi-mi:HRT1(display_short)|uniprotkb:RBX1(gene name synonym)|uniprotkb:ROC1(gene name synonym)|uniprotkb:Regulator of cullins protein 1(gene name synonym)|uniprotkb:YOL133W(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11546732|imex:IM-24995-2575	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001154993.1|refseq:NP_001154994.1|refseq:NP_009177.3|refseq:NP_001317952.1|refseq:NP_001317953.1|refseq:XP_016863165.1|ensembl:ENSG00000109466(gene)|ensembl:ENST00000226725(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030027"(lamellipodium)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR017096(Kelch-like protein, gigaxonin)|interpro:IPR044072|mint:O95198|rcsb pdb:2XN4|rcsb pdb:4CHB|reactome:R-HSA-8951664|reactome:R-HSA-983168|go:"GO:0042802"(identical protein binding)|entrezgene/locuslink:11275(identity)	refseq:NP_014508.1|sgd:S000005493|dip:DIP-1373N|mint:Q08273|ensemblfungi:YOL133W(gene)|ensemblfungi:YOL133W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0035361"(Cul8-RING ubiquitin ligase complex)|go:"GO:0051301"(cell division)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097602"(cullin family protein binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR024766|reactome:R-SCE-5696395|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-68949|reactome:R-SCE-8854050|reactome:R-SCE-8951664|reactome:R-SCE-983168|sgd:YOL133W(identity)	-	-	crc64:A9C3193E48CAF881	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:tFegR2lJZccRqs4qUjdT3PNjNnk9606	rogid:7LBUfvb6zpWuPkbMDrEAnrMuJj8559292	intact-crc:1F36B11DBCE6A935|rigid:+ylwumnTyxVdpdyc4oGWKo865Bg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O43791	uniprotkb:Q08273	intact:EBI-743549|uniprotkb:Q53HJ1|uniprotkb:B2R6S3|uniprotkb:D3DTW7|ensembl:ENSP00000240327|ensembl:ENSP00000377001|ensembl:ENSP00000420908|ensembl:ENSP00000424119|ensembl:ENSP00000425905|ensembl:ENSP00000426986|ensembl:ENSP00000499562	intact:EBI-31686|uniprotkb:D6W1T5|ensemblfungi:YOL133W	psi-mi:spop_human(display_long)|uniprotkb:HIB homolog 1(gene name synonym)|uniprotkb:Roadkill homolog 1(gene name synonym)|uniprotkb:SPOP(gene name)|psi-mi:SPOP(display_short)	psi-mi:rbx1_yeast(display_long)|uniprotkb:E3 ubiquitin-protein ligase complex SCF subunit HRT1(gene name synonym)|uniprotkb:High level expression reduces Ty3 transposition protein 1(gene name synonym)|uniprotkb:HRT1(gene name)|psi-mi:HRT1(display_short)|uniprotkb:RBX1(gene name synonym)|uniprotkb:ROC1(gene name synonym)|uniprotkb:Regulator of cullins protein 1(gene name synonym)|uniprotkb:YOL133W(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11546723|imex:IM-24995-2574	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001007227.1|refseq:NP_001007228.1|refseq:NP_001007229.1|refseq:NP_001007230.1|refseq:NP_001007231.1|refseq:NP_003554.1|refseq:XP_005257780.1|refseq:XP_005257781.1|ensembl:ENSG00000121067(gene)|ensembl:ENST00000347630(transcript)|ensembl:ENST00000393328(transcript)|ensembl:ENST00000503676(transcript)|ensembl:ENST00000504102(transcript)|ensembl:ENST00000509079(transcript)|ensembl:ENST00000514121(transcript)|ensembl:ENST00000665825(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0016607"(nuclear speck)|go:"GO:0030162"(regulation of proteolysis)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR034089|mint:O43791|rcsb pdb:2CR2|rcsb pdb:3HQH|rcsb pdb:3HQI|rcsb pdb:3HQL|rcsb pdb:3HQM|rcsb pdb:3HSV|rcsb pdb:3HTM|rcsb pdb:3HU6|rcsb pdb:3IVB|rcsb pdb:3IVQ|rcsb pdb:3IVV|rcsb pdb:4EOZ|rcsb pdb:4HS2|rcsb pdb:4J8Z|rcsb pdb:4O1V|rcsb pdb:6F8F|rcsb pdb:6F8G|rcsb pdb:6I41|rcsb pdb:6I5P|rcsb pdb:6I68|rcsb pdb:6I7A|rcsb pdb:7D3D|rcsb pdb:7LIN|rcsb pdb:7LIO|rcsb pdb:7LIP|rcsb pdb:7LIQ|reactome:R-HSA-5632684|go:"GO:0005634"(nucleus)|refseq:XP_016880693.1|dip:DIP-50517N|entrezgene/locuslink:8405(identity)	refseq:NP_014508.1|sgd:S000005493|dip:DIP-1373N|mint:Q08273|ensemblfungi:YOL133W(gene)|ensemblfungi:YOL133W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0035361"(Cul8-RING ubiquitin ligase complex)|go:"GO:0051301"(cell division)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097602"(cullin family protein binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR024766|reactome:R-SCE-5696395|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-68949|reactome:R-SCE-8854050|reactome:R-SCE-8951664|reactome:R-SCE-983168|sgd:YOL133W(identity)	-	-	crc64:A9C3193E48CAF881	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:PC9ofpvk14xwTnnqT590/YRnx/49606	rogid:7LBUfvb6zpWuPkbMDrEAnrMuJj8559292	intact-crc:E50DD2C6A86C6537|rigid:6/futgV6DhTWGv/wADWCfT5Ndw4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q08224	uniprotkb:Q9C0F1	intact:EBI-35298|uniprotkb:Q05664|uniprotkb:Q6B2F0|uniprotkb:D6W212|ensemblfungi:YOL055C	intact:EBI-744115|uniprotkb:A8K8W9|uniprotkb:B3KT53|uniprotkb:Q8IXZ4|uniprotkb:A8MW11|uniprotkb:D3DP42|ensembl:ENSP00000296519|ensembl:ENSP00000380009|ensembl:ENSP00000423153	psi-mi:thi20_yeast(display_long)|uniprotkb:THI20(gene name)|psi-mi:THI20(display_short)|uniprotkb:Hydroxymethylpyrimidine kinase(gene name synonym)|uniprotkb:YOL055C(locus name)|uniprotkb:O1239(orf name)|uniprotkb:Hydroxymethylpyrimidine phosphate kinase(gene name synonym)	psi-mi:cep44_human(display_long)|uniprotkb:HBV PreS1-transactivated protein 3(gene name synonym)|uniprotkb:CEP44(gene name)|psi-mi:CEP44(display_short)|uniprotkb:KIAA1712(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11546714|imex:IM-24995-2573	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014586.1|sgd:S000005416|dip:DIP-8852N|ensemblfungi:YOL055C(gene)|ensemblfungi:YOL055C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0008902"(hydroxymethylpyrimidine kinase activity)|go:"GO:0008972"(phosphomethylpyrimidine kinase activity)|go:"GO:0009228"(thiamine biosynthetic process)|go:"GO:0009229"(thiamine diphosphate biosynthetic process)|go:"GO:0009230"(thiamine catabolic process)|go:"GO:0050334"(thiaminase activity)|interpro:IPR004305(TENA/THI-4 protein/Coenzyme PQQ biosynthesis protein C)|interpro:IPR004399(Phosphomethylpyrimidine kinase type-2)|interpro:IPR013749(Phosphomethylpyrimidine kinase type-1)|interpro:IPR016084(Haem oxygenase-like, multi-helical)|interpro:IPR027574|interpro:IPR029056|rcsb pdb:3RM5|sgd:YOL055C(identity)	refseq:NP_001035247.1|refseq:NP_001138786.1|refseq:XP_011530587.1|refseq:XP_011530588.1|refseq:XP_011530589.1|refseq:XP_016864143.1|refseq:XP_016864144.1|ensembl:ENSG00000164118(gene)|ensembl:ENST00000296519(transcript)|ensembl:ENST00000396791(transcript)|ensembl:ENST00000503780(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007099"(centriole replication)|go:"GO:0008017"(microtubule binding)|go:"GO:0010457"(centriole-centriole cohesion)|go:"GO:0030496"(midbody)|interpro:IPR029157|interpro:IPR033603|mint:Q9C0F1|entrezgene/locuslink:80817(identity)	-	crc64:D57D1C6B693EE401	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:8Z2moCtUE4aAGFn00SHe4PMjdT4559292	rogid:gDTC64oDhudGdsssC7v+suIHZkA9606	intact-crc:161748ED1B834DB2|rigid:uD4lCFeYF3kBtM74SDEXQnnErKA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9Y2D8	uniprotkb:Q08204	intact:EBI-2212028|uniprotkb:B4DFE3|uniprotkb:J3KR02|uniprotkb:A8K8W0|uniprotkb:D3DT13|uniprotkb:Q6P2P8|uniprotkb:Q6ULS1|uniprotkb:Q7L168|uniprotkb:Q9UIX0|intact:EBI-10964529|ensembl:ENSP00000340279	intact:EBI-34125|uniprotkb:D6W231|ensemblfungi:YOL034W	psi-mi:adip_human(display_long)|uniprotkb:SSX2IP(gene name)|psi-mi:SSX2IP(display_short)|uniprotkb:KIAA0923(gene name synonym)|uniprotkb:Afadin DIL domain-interacting protein(gene name synonym)|uniprotkb:SSX2-interacting protein(gene name synonym)	psi-mi:smc5_yeast(display_long)|uniprotkb:SMC5(gene name)|psi-mi:SMC5(display_short)|uniprotkb:YOL034W(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11546705|imex:IM-24995-2572	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011538912.1|refseq:NP_001159765.1|refseq:NP_001159766.1|refseq:NP_001159767.1|refseq:NP_001159889.1|refseq:NP_054740.3|refseq:XP_005270484.1|refseq:XP_005270485.1|refseq:XP_006710394.1|refseq:XP_016855723.1|ensembl:ENSG00000117155(gene)|ensembl:ENST00000342203(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005912"(adherens junction)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031252"(cell leading edge)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0035735"(intraciliary transport involved in cilium assembly)|go:"GO:0036064"(ciliary basal body)|go:"GO:0060271"(cilium assembly)|go:"GO:2000145"(regulation of cell motility)|interpro:IPR021622|mint:Q9Y2D8|entrezgene/locuslink:117178(identity)	refseq:NP_014608.1|sgd:S000005394|mint:Q08204|dip:DIP-1979N|ensemblfungi:YOL034W(gene)|ensemblfungi:YOL034W_mRNA(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000725"(recombinational repair)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006281"(DNA repair)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0016925"(protein sumoylation)|go:"GO:0030915"(Smc5-Smc6 complex)|go:"GO:0051304"(chromosome separation)|go:"GO:0071139"(resolution of recombination intermediates)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR027131|interpro:IPR027417|rcsb pdb:3HTK|reactome:R-SCE-3108214|sgd:YOL034W(identity)	-	-	crc64:6752B96438CFB549	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:E0VeMRF9SrpQKSJFP01XEbMjeF89606	rogid:7EBoBNiTfotgfzhZ2+a+PcQTAqc559292	intact-crc:4ECD503C89F92548|rigid:wstO6eypXHeYmVjGP2B+Nh8mE2M	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12006	uniprotkb:Q969F0	intact:EBI-36378|uniprotkb:D6W264|ensemblfungi:YOL003C	intact:EBI-743099|ensembl:ENSP00000359375	psi-mi:pfa4_yeast(display_long)|uniprotkb:PFA4(gene name)|psi-mi:PFA4(display_short)|uniprotkb:UNE378(orf name)|uniprotkb:Protein fatty acyltransferase 4(gene name synonym)|uniprotkb:YOL003C(locus name)|uniprotkb:Protein S-acyltransferase(gene name synonym)	psi-mi:fate1_human(display_long)|uniprotkb:Tumor antigen BJ-HCC-2(gene name synonym)|uniprotkb:Cancer/testis antigen 43(gene name synonym)|uniprotkb:FATE1(gene name)|psi-mi:FATE1(display_short)|uniprotkb:FATE(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11546824|imex:IM-24995-2585	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014640.1|sgd:S000005363|dip:DIP-4248N|reactome:R-SCE-203615|ensemblfungi:YOL003C(gene)|ensemblfungi:YOL003C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR033682|sgd:YOL003C(identity)	refseq:NP_149076.1|ensembl:ENSG00000147378(gene)|ensembl:ENST00000370350(transcript)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|go:"GO:0051562"(negative regulation of mitochondrial calcium ion concentration)|interpro:IPR039153|interpro:IPR039433|mint:Q969F0|entrezgene/locuslink:89885(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:yzNswK8Xpbra0kf0p0cRh+CXCqo559292	rogid:Nm1N6lO92MHr5rIKC007oouF5RE9606	intact-crc:0671C356A420D051|rigid:3rCoXocZsVRHENUsM9wJMEg03BE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q10740	uniprotkb:Q8N9N5-2	intact:EBI-10175|uniprotkb:D6W1D4|ensemblfungi:YNL045W	intact:EBI-11524452|ensembl:ENSP00000347125	psi-mi:lkha4_yeast(display_long)|uniprotkb:LAP2(gene name)|psi-mi:LAP2(display_short)|uniprotkb:Epoxide hydrolase(gene name synonym)|uniprotkb:Leucyl aminopeptidase yscIV(gene name synonym)|uniprotkb:Leukotriene A-4 hydrolase homolog(gene name synonym)|uniprotkb:N2535(orf name)|uniprotkb:YNL045W(locus name)	psi-mi:q8n9n5-2(display_long)|uniprotkb:BANP(gene name)|psi-mi:BANP(display_short)|uniprotkb:BEN domain-containing protein 1(gene name synonym)|uniprotkb:BEND1(gene name synonym)|uniprotkb:Btg3-associated nuclear protein(gene name synonym)|uniprotkb:SMAR1(gene name synonym)|uniprotkb:Scaffold/matrix-associated region-1-binding protein(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11546815|imex:IM-24995-2584	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014353.1|sgd:S000004990|go:"GO:0008270"(zinc ion binding)|go:"GO:0030163"(protein catabolic process)|go:"GO:0043171"(peptide catabolic process)|go:"GO:0044255"(cellular lipid metabolic process)|ensemblfungi:YNL045W(gene)|ensemblfungi:YNL045W_mRNA(transcript)|go:"GO:0004177"(aminopeptidase activity)|go:"GO:0004301"(epoxide hydrolase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|interpro:IPR001930(Peptidase M1, membrane alanine aminopeptidase)|go:"GO:0005829"(cytosol)|interpro:IPR012777(Leukotriene A-4 hydrolase/aminopeptidase)|go:"GO:0008237"(metallopeptidase activity)|interpro:IPR014782(Peptidase M1, membrane alanine aminopeptidase, N-terminal)|interpro:IPR015211(Peptidase M1, leukotriene A4 hydrolase, aminopeptidase C-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027268|interpro:IPR034015|interpro:IPR038502|interpro:IPR042097|rcsb pdb:2XPZ|rcsb pdb:2XQ0|reactome:R-SCE-2142691|reactome:R-SCE-6798695|reactome:R-SCE-9018676|reactome:R-SCE-9018681|reactome:R-SCE-9018896|reactome:R-SCE-9020265|rcsb pdb:2XPY|reactome:R-SCE-9023661|dip:DIP-4371N|mint:Q10740|sgd:YNL045W(identity)	ensembl:ENSG00000172530(gene)|ensembl:ENST00000355022(transcript)|intact:EBI-744695(isoform-parent)|uniprotkb:Q8N9N5-2(isoform-parent)|entrezgene/locuslink:54971(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:CqwX8n+boaHaneIOt/jhsAJngF8559292	rogid:ESe6iCAhvq+i57fQHz3rGyg6UOo9606	intact-crc:5C756784A95826C3|rigid:WO1wZSHxzAEB5Qw2g2FiUe0x0xk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P62258	uniprotkb:Q08981	intact:EBI-356498|uniprotkb:P29360|uniprotkb:P42655|uniprotkb:Q53XZ5|uniprotkb:Q63631|uniprotkb:Q7M4R4|uniprotkb:B3KY71|uniprotkb:D3DTH5|uniprotkb:Q4VJB6|ensembl:ENSP00000264335|ensembl:ENSP00000487356	intact:EBI-2345174|uniprotkb:D6W3A3|ensemblfungi:YPL267W	psi-mi:1433e_human(display_long)|uniprotkb:YWHAE(gene name)|psi-mi:YWHAE(display_short)	psi-mi:acm1_yeast(display_long)|uniprotkb:ACM1(gene name)|psi-mi:ACM1(display_short)|uniprotkb:YPL267W(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11546806|imex:IM-24995-2583	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006752.1|dip:DIP-36676N|reactome:R-HSA-1445148|reactome:R-HSA-2028269|reactome:R-HSA-205025|reactome:R-HSA-2565942|reactome:R-HSA-3371453|reactome:R-HSA-3371511|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-75035|reactome:R-HSA-8854518|reactome:R-HSA-8862803|reactome:R-HSA-8876198|ensembl:ENSG00000108953(gene)|ensembl:ENSG00000274474(gene)|ensembl:ENST00000264335(transcript)|ensembl:ENST00000627231(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0003064"(regulation of heart rate by hormone)|go:"GO:0003723"(RNA binding)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005925"(focal adhesion)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050815"(phosphoserine residue binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099072"(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:"GO:1901016"(regulation of potassium ion transmembrane transporter activity)|go:"GO:1901020"(negative regulation of calcium ion transmembrane transporter activity)|go:"GO:1902309"(negative regulation of peptidyl-serine dephosphorylation)|go:"GO:1905913"(negative regulation of calcium ion export across plasma membrane)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P62258|rcsb pdb:2BR9|rcsb pdb:3UAL|rcsb pdb:3UBW|rcsb pdb:6EIH|rcsb pdb:7C8E|reactome:R-HSA-111447|entrezgene/locuslink:7531(identity)	sgd:S000006188|refseq:NP_015056.1|dip:DIP-8871N|mint:Q08981|ensemblfungi:YPL267W(gene)|ensemblfungi:YPL267W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0051301"(cell division)|go:"GO:0055105"(ubiquitin-protein transferase inhibitor activity)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|rcsb pdb:4BH6|sgd:YPL267W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:mnuAjdnQZbMFojll2PnV3xFklXQ9606	rogid:WiRejHsJpiS1aSY3PJUzdRflynM559292	intact-crc:95A7CB49910355DD|rigid:ilpXeDffZ4W4kHLt6mvDI0gWYeY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q08909	uniprotkb:O14641	intact:EBI-36654|uniprotkb:D6W378|ensemblfungi:YOR385W	intact:EBI-740850|ensembl:ENSP00000005340|uniprotkb:Q53XM0|uniprotkb:D3DTN3	psi-mi:yo385_yeast(display_long)|uniprotkb:YOR385W(locus name)	psi-mi:dvl2_human(display_long)|uniprotkb:DSH homolog 2(gene name synonym)|uniprotkb:DVL2(gene name)|psi-mi:DVL2(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11546797|imex:IM-24995-2582	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005912|refseq:NP_015030.3|dip:DIP-4047N|ensemblfungi:YOR385W(gene)|ensemblfungi:YOR385W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|sgd:YOR385W(identity)	refseq:NP_004413.1|ensembl:ENSG00000004975(gene)|ensembl:ENST00000005340(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005109"(frizzled binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0007507"(heart development)|go:"GO:0016235"(aggresome)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044340"(canonical Wnt signaling pathway involved in regulation of cell proliferation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0150012"(positive regulation of neuron projection arborization)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008341(Dishevelled-2 region)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:O14641|rcsb pdb:2REY|rcsb pdb:3CBX|rcsb pdb:3CBY|rcsb pdb:3CBZ|rcsb pdb:3CC0|rcsb pdb:4WIP|rcsb pdb:5LNP|rcsb pdb:5SUY|rcsb pdb:5SUZ|rcsb pdb:6IW3|rcsb pdb:6JCK|reactome:R-HSA-201681|reactome:R-HSA-201688|reactome:R-HSA-2028269|reactome:R-HSA-4086400|reactome:R-HSA-4608870|reactome:R-HSA-4641258|reactome:R-HSA-4641262|reactome:R-HSA-5099900|reactome:R-HSA-5368598|reactome:R-HSA-5663220|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9673324|ensembl:ENSP00000005340|dip:DIP-34433N|entrezgene/locuslink:1856(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:8SWTqlDNdzFcWIa8miL9cz87Peg559292	rogid:2Vdc8oRnT4Mz/j+EXQXrL3AszOc9606	intact-crc:CAA144AAE9CB1DA0|rigid:jgeiMmVQa2XQYTNFI1203W6IS4w	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O00308	uniprotkb:Q08909	intact:EBI-743923|uniprotkb:H3BRF3|uniprotkb:Q6ZTQ5|uniprotkb:A6NEP1|uniprotkb:Q96CZ2|uniprotkb:Q9BWN6|uniprotkb:B2R706|uniprotkb:B4DTL5|uniprotkb:F5H213|uniprotkb:I3RSG8|ensembl:ENSP00000352069	intact:EBI-36654|uniprotkb:D6W378|ensemblfungi:YOR385W	psi-mi:wwp2_human(display_long)|uniprotkb:WW domain-containing protein 2(gene name synonym)|uniprotkb:Atrophin-1-interacting protein 2(gene name synonym)|uniprotkb:WWP2(gene name)|psi-mi:WWP2(display_short)|uniprotkb:HECT-type E3 ubiquitin transferase WWP2(gene name synonym)	psi-mi:yo385_yeast(display_long)|uniprotkb:YOR385W(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11546788|imex:IM-24995-2581	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_008945.2|refseq:NP_001257383.1|refseq:NP_001257384.1|refseq:XP_011521125.1|refseq:XP_011521127.1|refseq:XP_011521128.1|refseq:NP_001257382.1|refseq:NP_955456.1|refseq:XP_016878368.1|refseq:XP_016878369.1|refseq:XP_016878370.1|ensembl:ENSG00000198373(gene)|ensembl:ENST00000359154(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006858"(extracellular transport)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032410"(negative regulation of transporter activity)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0051224"(negative regulation of protein transport)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:1901016"(regulation of potassium ion transmembrane transporter activity)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000569(HECT)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR024928|interpro:IPR035892|interpro:IPR035983|interpro:IPR036020|mint:O00308|rcsb pdb:4Y07|rcsb pdb:5TJ7|rcsb pdb:5TJ8|rcsb pdb:5TJQ|rcsb pdb:6J1Z|rcsb pdb:6RSS|reactome:R-HSA-8948751|reactome:R-HSA-9013406|reactome:R-HSA-9013409|reactome:R-HSA-9013420|reactome:R-HSA-9013507|entrezgene/locuslink:11060(identity)	sgd:S000005912|refseq:NP_015030.3|dip:DIP-4047N|ensemblfungi:YOR385W(gene)|ensemblfungi:YOR385W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|sgd:YOR385W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Xj0Xssn75HP9sp/tHNe4n83eHPE9606	rogid:8SWTqlDNdzFcWIa8miL9cz87Peg559292	intact-crc:7DF08019624C5300|rigid:GQDfiNCenB5G/dc71iclN6YSxhg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q08686	uniprotkb:Q92748	intact:EBI-19264|uniprotkb:D6W2V2|ensemblfungi:YOR251C	intact:EBI-1749955|uniprotkb:B2R4W7|ensembl:ENSP00000281030	psi-mi:thtr_yeast(display_long)|uniprotkb:YOR251C(locus name)|uniprotkb:TUM1(gene name)|psi-mi:TUM1(display_short)|uniprotkb:Thiouridine modification protein 1(gene name synonym)	psi-mi:thrsp_human(display_long)|uniprotkb:THRSP(gene name)|psi-mi:THRSP(display_short)|uniprotkb:Spot 14 protein(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11546779|imex:IM-24995-2580	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005777|ensemblfungi:YOR251C(gene)|ensemblfungi:YOR251C_mRNA(transcript)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0002143"(tRNA wobble position uridine thiolation)|go:"GO:0004792"(thiosulfate sulfurtransferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0019346"(transsulfuration)|interpro:IPR001307(Thiosulphate sulphurtransferase, conserved site)|interpro:IPR001763(Rhodanese-like)|interpro:IPR036873|rcsb pdb:3UTN|refseq:NP_014894.3|dip:DIP-4457N|reactome:R-SCE-1614558|sgd:YOR251C(identity)	dip:DIP-40451N|refseq:NP_003242.1|ensembl:ENSG00000151365(gene)|ensembl:ENST00000281030(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0009617"(response to bacterium)|go:"GO:0010866"(regulation of triglyceride biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046890"(regulation of lipid biosynthetic process)|interpro:IPR009786(Thyroid hormone-inducible hepatic Spot 14)|mint:Q92748|reactome:R-HSA-200425|entrezgene/locuslink:7069(identity)	-	crc64:F8082DF7CC279E82	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Hd0nLXm0qNzaqJcSHt/nV73+Pko559292	rogid:tkQQSNiBkUIynoBVT5olWEkCX/o9606	intact-crc:2BCD596F2BDC3E17|rigid:frlWGUDksTUPQXs1A9qSmEDDGYs	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q08581	uniprotkb:P63279	intact:EBI-38556|uniprotkb:D6W2Q4|ensemblfungi:YOR195W	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	psi-mi:slk19_yeast(display_long)|uniprotkb:Synthetic lethal KAR3 protein 19(gene name synonym)|uniprotkb:SLK19(gene name)|psi-mi:SLK19(display_short)|uniprotkb:YOR195W(locus name)	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11546770|imex:IM-24995-2579	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005721|refseq:NP_014838.3|mint:Q08581|dip:DIP-2595N|ensemblfungi:YOR195W(gene)|ensemblfungi:YOR195W_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0005819"(spindle)|go:"GO:0005874"(microtubule)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007097"(nuclear migration)|go:"GO:0031536"(positive regulation of exit from mitosis)|go:"GO:0051233"(spindle midzone)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0098653"(centromere clustering)|interpro:IPR024312|sgd:YOR195W(identity)	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N|entrezgene/locuslink:7329(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:3ufBU9ElgshvxT7WluCx2lQX2Rs559292	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	intact-crc:D27E53A402AB1146|rigid:siA94kDoSEEwM7+nLStLP0Fb7w8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q08438	uniprotkb:Q96CD2	intact:EBI-30482|uniprotkb:O00019|uniprotkb:D6W2B8|ensemblfungi:YOR054C	intact:EBI-724333|uniprotkb:Q96SX0|ensembl:ENSP00000343190|uniprotkb:Q9HC17	psi-mi:vhs3_yeast(display_long)|uniprotkb:Viable in a HAL3 SIT4 background protein 3(gene name synonym)|uniprotkb:VHS3(gene name)|psi-mi:VHS3(display_short)|uniprotkb:YOR054C(locus name)|uniprotkb:YOR29-05(orf name)	psi-mi:coac_human(display_long)|uniprotkb:CoaC(gene name synonym)|uniprotkb:PPCDC(gene name)|psi-mi:PPCDC(display_short)|uniprotkb:COAC(gene name synonym)|uniprotkb:MDS018(orf name)|uniprotkb:UNQ9365/PRO34154(orf name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11546761|imex:IM-24995-2578	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014697.1|sgd:S000005580|dip:DIP-4172N|mint:Q08438|ensemblfungi:YOR054C(gene)|ensemblfungi:YOR054C_mRNA(transcript)|go:"GO:0003824"(catalytic activity)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0007049"(cell cycle)|go:"GO:0010181"(FMN binding)|go:"GO:0015937"(coenzyme A biosynthetic process)|go:"GO:0030004"(cellular monovalent inorganic cation homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0071513"(phosphopantothenoylcysteine decarboxylase complex)|go:"GO:1990143"(CoA-synthesizing protein complex)|interpro:IPR003382(Flavoprotein)|interpro:IPR036551|sgd:YOR054C(identity)	refseq:NP_068595.3|rcsb pdb:1QZU|reactome:R-HSA-196783|mint:Q96CD2|ensembl:ENSG00000138621(gene)|ensembl:ENST00000342932(transcript)|go:"GO:0004633"(phosphopantothenoylcysteine decarboxylase activity)|go:"GO:0005829"(cytosol)|go:"GO:0010181"(FMN binding)|go:"GO:0015937"(coenzyme A biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0071513"(phosphopantothenoylcysteine decarboxylase complex)|interpro:IPR003382(Flavoprotein)|interpro:IPR036551|refseq:NP_001288030.1|refseq:NP_001288031.1|refseq:NP_001288032.1|refseq:NP_001288033.1|refseq:NP_001288034.1|entrezgene/locuslink:60490(identity)	-	crc64:A97623473CB6F605	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:xBrkL/88mlDFkk10q3ASQnr0rv0559292	rogid:2d686R1m4jA5uWpf/8O6rI6/Olo9606	intact-crc:71B2854741508886|rigid:lDnVx8Qzd0Iw7P3JjS6ee4Lw1FE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UH77	uniprotkb:Q08273	intact:EBI-8524663|uniprotkb:Q9ULU0|uniprotkb:B2RBK7|intact:UNK-6172988|uniprotkb:Q9UH76|uniprotkb:Q9UH75|uniprotkb:Q9Y6V6|ensembl:ENSP00000312397	intact:EBI-31686|uniprotkb:D6W1T5|ensemblfungi:YOL133W	psi-mi:klhl3_human(display_long)|uniprotkb:KLHL3(gene name)|psi-mi:KLHL3(display_short)|uniprotkb:KIAA1129(gene name synonym)	psi-mi:rbx1_yeast(display_long)|uniprotkb:E3 ubiquitin-protein ligase complex SCF subunit HRT1(gene name synonym)|uniprotkb:High level expression reduces Ty3 transposition protein 1(gene name synonym)|uniprotkb:HRT1(gene name)|psi-mi:HRT1(display_short)|uniprotkb:RBX1(gene name synonym)|uniprotkb:ROC1(gene name synonym)|uniprotkb:Regulator of cullins protein 1(gene name synonym)|uniprotkb:YOL133W(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11546750|imex:IM-24995-2577	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_059111.2|refseq:NP_001244124.1|refseq:NP_001244123.1|ensembl:ENSG00000146021(gene)|ensembl:ENST00000309755(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0050801"(ion homeostasis)|go:"GO:0061912"(selective autophagy)|go:"GO:0070294"(renal sodium ion absorption)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0072156"(distal tubule morphogenesis)|go:"GO:0097602"(cullin family protein binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR017096(Kelch-like protein, gigaxonin)|interpro:IPR030578|rcsb pdb:4CH9|rcsb pdb:4HXI|rcsb pdb:5NKP|reactome:R-HSA-8951664|reactome:R-HSA-983168|entrezgene/locuslink:26249(identity)	refseq:NP_014508.1|sgd:S000005493|dip:DIP-1373N|mint:Q08273|ensemblfungi:YOL133W(gene)|ensemblfungi:YOL133W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0035361"(Cul8-RING ubiquitin ligase complex)|go:"GO:0051301"(cell division)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097602"(cullin family protein binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR024766|reactome:R-SCE-5696395|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-68949|reactome:R-SCE-8854050|reactome:R-SCE-8951664|reactome:R-SCE-983168|sgd:YOL133W(identity)	-	comment:mint|comment:homomint|function:Probable substrate-specific adapter of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins	crc64:A9C3193E48CAF881	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:6iZNPY/wNDhLlUWeFLl0FyqtFXM9606	rogid:7LBUfvb6zpWuPkbMDrEAnrMuJj8559292	intact-crc:42B7F5B07A0555A4|rigid:stfWFAyIC45liOFdXxuWXPy9o8Y	false	sufficient binding region:1-301	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q08379	uniprotkb:Q12056	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	intact:EBI-30488|uniprotkb:D6W2T0|ensemblfungi:YOR226C	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:isu2_yeast(display_long)|uniprotkb:Iron sulfur cluster scaffold protein 2(gene name synonym)|uniprotkb:ISU2(gene name)|psi-mi:ISU2(display_short)|uniprotkb:NUA2(gene name synonym)|uniprotkb:YOR226C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11546892|imex:IM-24995-2592	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N|entrezgene/locuslink:2801(identity)	sgd:S000005752|refseq:NP_014869.3|dip:DIP-4123N|ensemblfungi:YOR226C(gene)|ensemblfungi:YOR226C_mRNA(transcript)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005737"(cytoplasm)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR002871(NIF system FeS cluster assembly, NifU, N-terminal)|interpro:IPR011339(ISC system FeS cluster assembly, IscU scaffold)|sgd:YOR226C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2017/05/26	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	rogid:e4qx7ic8wpO6cTHGl73je/JVzMY559292	intact-crc:6531EFF66A2C1B54|rigid:s6Eve3irpeAd2PIjh9OxC3n5OJs	false	sufficient binding region:383-1002	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12055	uniprotkb:Q8N7W2-2	intact:EBI-22197|uniprotkb:D6VRI5|uniprotkb:E9P8W4|ensemblfungi:YDL166C	intact:EBI-10181188|ensembl:ENSP00000367868	psi-mi:kad6_yeast(display_long)|uniprotkb:FAP7(gene name)|psi-mi:FAP7(display_short)|uniprotkb:POS9-activating factor 7(gene name synonym)|uniprotkb:YDL166C(locus name)|uniprotkb:Dual activity adenylate kinase/ATPase(gene name synonym)	psi-mi:q8n7w2-2(display_long)|uniprotkb:C10orf30(gene name synonym)|uniprotkb:BEND7(gene name)|psi-mi:BEND7(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11546881|imex:IM-24995-2591	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010115.1|sgd:S000002325|reactome:R-SCE-499943|dip:DIP-4793N|ensemblfungi:YDL166C(gene)|ensemblfungi:YDL166C_mRNA(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0004017"(adenylate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0034599"(cellular response to oxidative stress)|interpro:IPR020618|interpro:IPR027417|sgd:YDL166C(identity)	ensembl:ENSG00000165626(gene)|ensembl:ENST00000378605(transcript)|intact:EBI-743382(isoform-parent)|uniprotkb:Q8N7W2-2(isoform-parent)|entrezgene/locuslink:222389(identity)	-	crc64:836A25B0D7E2633C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:/hVE29n+kxI3CjMUlxtJxrvUpYk559292	rogid:p6qrTn80hLyVU0W2Tvwn50Q4m5I9606	intact-crc:E5B020F34469ADC6|rigid:tc2fv+VlLxFnsV55ohYeDNQErD8	false	-	sufficient binding region:10-374	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12055	uniprotkb:Q13164	intact:EBI-22197|uniprotkb:D6VRI5|uniprotkb:E9P8W4|ensemblfungi:YDL166C	intact:EBI-1213983|uniprotkb:Q16634|uniprotkb:Q59F50|uniprotkb:Q6QLU7|uniprotkb:Q7L4P4|uniprotkb:Q969G1|uniprotkb:Q96G51|intact:EBI-28979986|ensembl:ENSP00000311005|ensembl:ENSP00000378966|ensembl:ENSP00000378968	psi-mi:kad6_yeast(display_long)|uniprotkb:FAP7(gene name)|psi-mi:FAP7(display_short)|uniprotkb:POS9-activating factor 7(gene name synonym)|uniprotkb:YDL166C(locus name)|uniprotkb:Dual activity adenylate kinase/ATPase(gene name synonym)	psi-mi:mk07_human(display_long)|uniprotkb:MAPK7(gene name)|psi-mi:MAPK7(display_short)|uniprotkb:BMK1(gene name synonym)|uniprotkb:ERK5(gene name synonym)|uniprotkb:PRKM7(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 5(gene name synonym)|uniprotkb:Big MAP kinase 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11546870|imex:IM-24995-2590	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010115.1|sgd:S000002325|reactome:R-SCE-499943|dip:DIP-4793N|ensemblfungi:YDL166C(gene)|ensemblfungi:YDL166C_mRNA(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0004017"(adenylate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0034599"(cellular response to oxidative stress)|interpro:IPR020618|interpro:IPR027417|sgd:YDL166C(identity)	refseq:NP_002740.2|refseq:NP_620601.1|refseq:NP_620602.2|refseq:NP_620603.2|ensembl:ENST00000299612|ensembl:ENSP00000299612|ensembl:ENSP00000311005|ensembl:ENSP00000378966|ensembl:ENSP00000378968|refseq:XP_011522259.1|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0036003"(positive regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0051019"(mitogen-activated protein kinase binding)|go:"GO:0051247"(positive regulation of protein metabolic process)|go:"GO:0051344"(negative regulation of cyclic-nucleotide phosphodiesterase activity)|go:"GO:0060761"(negative regulation of response to cytokine stimulus)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071499"(cellular response to laminar fluid shear stress)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1902176"(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:2000352"(negative regulation of endothelial cell apoptotic process)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q13164|rcsb pdb:2Q8Y|rcsb pdb:4B99|rcsb pdb:4IC7|rcsb pdb:4IC8|rcsb pdb:4ZSG|rcsb pdb:4ZSJ|rcsb pdb:4ZSL|rcsb pdb:5BYY|rcsb pdb:5BYZ|rcsb pdb:5O7I|rcsb pdb:6HKM|rcsb pdb:6HKN|reactome:R-HSA-198753|reactome:R-HSA-198765|reactome:R-HSA-202670|reactome:R-HSA-2559582|reactome:R-HSA-881907|reactome:R-HSA-8853659|ensembl:ENSG00000166484(gene)|ensembl:ENST00000308406(transcript)|ensembl:ENST00000395602(transcript)|ensembl:ENST00000395604(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0016605"(PML body)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0030154"(cell differentiation)|go:"GO:0034115"(negative regulation of heterotypic cell-cell adhesion)|entrezgene/locuslink:5598(identity)	-	crc64:836A25B0D7E2633C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:/hVE29n+kxI3CjMUlxtJxrvUpYk559292	rogid:dUTMnlgdjEkFhq0i6RmvpX5U7BM9606	intact-crc:2E720A9E0CA2DD24|rigid:5P8RW0Uuz0dwmHid/nbNPuLrHSQ	false	-	sufficient binding region:140-816	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O95751	uniprotkb:Q12055	intact:EBI-740738|ensembl:ENSP00000359557|uniprotkb:Q6IAR6	intact:EBI-22197|uniprotkb:D6VRI5|uniprotkb:E9P8W4|ensemblfungi:YDL166C	psi-mi:ldoc1_human(display_long)|uniprotkb:Leucine zipper protein down-regulated in cancer cells(gene name synonym)|uniprotkb:LDOC1(gene name)|psi-mi:LDOC1(display_short)|uniprotkb:BCUR1(gene name synonym)	psi-mi:kad6_yeast(display_long)|uniprotkb:FAP7(gene name)|psi-mi:FAP7(display_short)|uniprotkb:POS9-activating factor 7(gene name synonym)|uniprotkb:YDL166C(locus name)|uniprotkb:Dual activity adenylate kinase/ATPase(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11546861|imex:IM-24995-2589	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_036449.1|ensembl:ENSG00000182195(gene)|ensembl:ENST00000370526(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071225"(cellular response to muramyl dipeptide)|interpro:IPR032549|interpro:IPR032567|entrezgene/locuslink:23641(identity)	refseq:NP_010115.1|sgd:S000002325|reactome:R-SCE-499943|dip:DIP-4793N|ensemblfungi:YDL166C(gene)|ensemblfungi:YDL166C_mRNA(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0004017"(adenylate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0034599"(cellular response to oxidative stress)|interpro:IPR020618|interpro:IPR027417|sgd:YDL166C(identity)	-	-	crc64:836A25B0D7E2633C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Ediu0oNiZ/+YVY8l3fNdgP5A+v09606	rogid:/hVE29n+kxI3CjMUlxtJxrvUpYk559292	intact-crc:749BD5DAD375F519|rigid:ekFS1249aT54NGZSYJuXfSriR8U	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P63279	uniprotkb:Q12020	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	intact:EBI-38714|uniprotkb:D6VY82|ensemblfungi:YLR082C	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:srl2_yeast(display_long)|uniprotkb:Suppressor of RAD53 null lethality protein 2(gene name synonym)|uniprotkb:SRL2(gene name)|psi-mi:SRL2(display_short)|uniprotkb:YLR082C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11546852|imex:IM-24995-2588	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N|entrezgene/locuslink:7329(identity)	sgd:S000004072|refseq:NP_013183.1|mint:Q12020|dip:DIP-1442N|ensemblfungi:YLR082C(gene)|ensemblfungi:YLR082C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006139"(nucleobase-containing compound metabolic process)|sgd:YLR082C(identity)	-	-	crc64:A39CD3D2E0F9BBF3	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	rogid:HVo/JUo9fmmcCD0iLScF47NCDrM559292	intact-crc:228F6732D86D342D|rigid:T6PAbjXxLoUlyOa/YM67dr1sJg8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12015	uniprotkb:Q9NX47	intact:EBI-31423|uniprotkb:D6W2S8|ensemblfungi:YOR223W	intact:EBI-2341610|ensembl:ENSP00000351813	psi-mi:dsc3_yeast(display_long)|uniprotkb:DSC3(gene name)|psi-mi:DSC3(display_short)|uniprotkb:Defective for SREBP cleavage protein 3(gene name synonym)|uniprotkb:YOR50-13(orf name)|uniprotkb:YOR223W(locus name)	psi-mi:marh5_human(display_long)|uniprotkb:MARCH5(gene name synonym)|uniprotkb:Membrane-associated RING finger protein 5(gene name synonym)|uniprotkb:Membrane-associated RING-CH protein V(gene name synonym)|uniprotkb:Mitochondrial ubiquitin ligase(gene name synonym)|uniprotkb:RING finger protein 153(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase MARCHF5(gene name synonym)|uniprotkb:MARCHF5(gene name)|psi-mi:MARCHF5(display_short)|uniprotkb:RNF153(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11546843|imex:IM-24995-2587	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014866.3|sgd:S000005749|interpro:IPR019413|interpro:IPR025390|ensemblfungi:YOR223W(gene)|ensemblfungi:YOR223W_mRNA(transcript)|go:"GO:0000328"(fungal-type vacuole lumen)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016485"(protein processing)|go:"GO:0044695"(Dsc E3 ubiquitin ligase complex)|sgd:YOR223W(identity)	refseq:NP_060294.1|ensembl:ENSG00000198060(gene)|ensembl:ENST00000358935(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0051020"(GTPase binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070585"(protein localization to mitochondrion)|go:"GO:0090140"(regulation of mitochondrial fission)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0090344"(negative regulation of cell aging)|interpro:IPR011016(Zinc finger, variant RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|mint:Q9NX47|entrezgene/locuslink:54708(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:ebWSvkqYXzLugE3xFfu285Cil8Y559292	rogid:/w+L/oINlKM5ZSm1OkI+R+8PxXg9606	intact-crc:2B10C776A52A2BD4|rigid:i4kciKb1mhGdajNeZoHVy8oStDY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96BA8	uniprotkb:Q12006	intact:EBI-6942903|ensembl:ENSP00000481956|intact:MINT-268046|intact:MINT-8162577|uniprotkb:Q8N2D5|uniprotkb:Q96CP0	intact:EBI-36378|uniprotkb:D6W264|ensemblfungi:YOL003C	psi-mi:cr3l1_human(display_long)|uniprotkb:CREB3L1(gene name)|psi-mi:CREB3L1(display_short)|uniprotkb:OASIS(gene name synonym)|uniprotkb:PSEC0238(orf name)|uniprotkb:Old astrocyte specifically-induced substance(gene name synonym)	psi-mi:pfa4_yeast(display_long)|uniprotkb:PFA4(gene name)|psi-mi:PFA4(display_short)|uniprotkb:UNE378(orf name)|uniprotkb:Protein fatty acyltransferase 4(gene name synonym)|uniprotkb:YOL003C(locus name)|uniprotkb:Protein S-acyltransferase(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11546833|imex:IM-24995-2586	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157613(gene)|ensembl:ENST00000621158(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0070278"(extracellular matrix constituent secretion)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029805|mint:Q96BA8|reactome:R-HSA-8874211|refseq:NP_443086.1|entrezgene/locuslink:90993(identity)	refseq:NP_014640.1|sgd:S000005363|dip:DIP-4248N|reactome:R-SCE-203615|ensemblfungi:YOL003C(gene)|ensemblfungi:YOL003C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR033682|sgd:YOL003C(identity)	-	comment:mint|function:"Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE"	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:sMWUFmBeBBCO+T0Y2CuB/un1lBg9606	rogid:yzNswK8Xpbra0kf0p0cRh+CXCqo559292	intact-crc:14E7EAFEA414F81A|rigid:j03lKme0dkUdMvCvlrnvcab836E	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12083	uniprotkb:Q9BRK4	intact:EBI-31634|uniprotkb:D6W3K4|ensemblfungi:YPL164C	intact:EBI-741037|ensembl:ENSP00000359240|ensembl:ENSP00000359243|uniprotkb:Q8N3I0|uniprotkb:Q96J79|uniprotkb:Q96JL2|uniprotkb:B1AL14|uniprotkb:D3DR72	psi-mi:mlh3_yeast(display_long)|uniprotkb:MLH3(gene name)|psi-mi:MLH3(display_short)|uniprotkb:MutL protein homolog 3(gene name synonym)|uniprotkb:P2550(orf name)|uniprotkb:YPL164C(locus name)	psi-mi:lzts2_human(display_long)|uniprotkb:Protein LAPSER1(gene name synonym)|uniprotkb:LZTS2(gene name)|psi-mi:LZTS2(display_short)|uniprotkb:KIAA1813(gene name synonym)|uniprotkb:LAPSER1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11546979|imex:IM-24995-2601	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015161.1|sgd:S000006085|dip:DIP-2414N|ensemblfungi:YPL164C(gene)|ensemblfungi:YPL164C_mRNA(transcript)|go:"GO:0000710"(meiotic mismatch repair)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006298"(mismatch repair)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0030983"(mismatched DNA binding)|go:"GO:0032300"(mismatch repair complex)|go:"GO:0097587"(MutLgamma complex)|interpro:IPR013507(DNA mismatch repair protein, C-terminal)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR014790(MutL, C-terminal, dimerisation)|interpro:IPR020568|interpro:IPR028830|interpro:IPR036890|interpro:IPR037198|interpro:IPR038973|interpro:IPR042120|rcsb pdb:6RMN|rcsb pdb:6SHX|rcsb pdb:6SNS|rcsb pdb:6SNV|sgd:YPL164C(identity)	refseq:NP_115805.1|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030496"(midbody)|go:"GO:0031982"(vesicle)|go:"GO:0051013"(microtubule severing)|go:"GO:0051168"(nuclear export)|go:"GO:0051255"(spindle midzone assembly)|go:"GO:0060682"(primary ureteric bud growth)|go:"GO:0072197"(ureter morphogenesis)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|interpro:IPR028597|mint:Q9BRK4|ensembl:ENSG00000107816(gene)|ensembl:ENST00000370220(transcript)|ensembl:ENST00000370223(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0008285"(negative regulation of cell population proliferation)|refseq:XP_016872269.1|refseq:NP_001305028.1|refseq:NP_001305029.1|refseq:NP_001305030.1|refseq:XP_005270279.1|entrezgene/locuslink:84445(identity)	-	crc64:970FD7F57EB6E3B1	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:g47/5yM9oWZ13CIZOZ7QT6A+LW0559292	rogid:OaMJmnmfm6JniKUJeyg7fS6zRcw9606	intact-crc:DAC0CC3FE130C663|rigid:tr5QsIWPV4A3k7Sonu0je+Nrc7w	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12083	uniprotkb:Q96CN4	intact:EBI-31634|uniprotkb:D6W3K4|ensemblfungi:YPL164C	intact:EBI-749523|uniprotkb:B9A6I9|ensembl:ENSP00000270530	psi-mi:mlh3_yeast(display_long)|uniprotkb:MLH3(gene name)|psi-mi:MLH3(display_short)|uniprotkb:MutL protein homolog 3(gene name synonym)|uniprotkb:P2550(orf name)|uniprotkb:YPL164C(locus name)	psi-mi:evi5l_human(display_long)|uniprotkb:Ecotropic viral integration site 5-like protein(gene name synonym)|uniprotkb:EVI5L(gene name)|psi-mi:EVI5L(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11546970|imex:IM-24995-2600	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015161.1|sgd:S000006085|dip:DIP-2414N|ensemblfungi:YPL164C(gene)|ensemblfungi:YPL164C_mRNA(transcript)|go:"GO:0000710"(meiotic mismatch repair)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006298"(mismatch repair)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0030983"(mismatched DNA binding)|go:"GO:0032300"(mismatch repair complex)|go:"GO:0097587"(MutLgamma complex)|interpro:IPR013507(DNA mismatch repair protein, C-terminal)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR014790(MutL, C-terminal, dimerisation)|interpro:IPR020568|interpro:IPR028830|interpro:IPR036890|interpro:IPR037198|interpro:IPR038973|interpro:IPR042120|rcsb pdb:6RMN|rcsb pdb:6SHX|rcsb pdb:6SNS|rcsb pdb:6SNV|sgd:YPL164C(identity)	refseq:NP_001153416.1|refseq:NP_660288.1|refseq:XP_005272515.1|refseq:XP_016881728.1|ensembl:ENSG00000142459(gene)|ensembl:ENST00000270530(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0031267"(small GTPase binding)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:1902018"(negative regulation of cilium assembly)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR031214|interpro:IPR035969|entrezgene/locuslink:115704(identity)	-	crc64:970FD7F57EB6E3B1	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:g47/5yM9oWZ13CIZOZ7QT6A+LW0559292	rogid:OKfnOqdRupGBmq6gqoeApO0cgG09606	intact-crc:DE0DD1CDF92870F0|rigid:IqZlr/B4ItdV/mbNSy7C61AoElM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12083	uniprotkb:O14641	intact:EBI-31634|uniprotkb:D6W3K4|ensemblfungi:YPL164C	intact:EBI-740850|ensembl:ENSP00000005340|uniprotkb:Q53XM0|uniprotkb:D3DTN3	psi-mi:mlh3_yeast(display_long)|uniprotkb:MLH3(gene name)|psi-mi:MLH3(display_short)|uniprotkb:MutL protein homolog 3(gene name synonym)|uniprotkb:P2550(orf name)|uniprotkb:YPL164C(locus name)	psi-mi:dvl2_human(display_long)|uniprotkb:DSH homolog 2(gene name synonym)|uniprotkb:DVL2(gene name)|psi-mi:DVL2(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11546961|imex:IM-24995-2599	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015161.1|sgd:S000006085|dip:DIP-2414N|ensemblfungi:YPL164C(gene)|ensemblfungi:YPL164C_mRNA(transcript)|go:"GO:0000710"(meiotic mismatch repair)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006298"(mismatch repair)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0030983"(mismatched DNA binding)|go:"GO:0032300"(mismatch repair complex)|go:"GO:0097587"(MutLgamma complex)|interpro:IPR013507(DNA mismatch repair protein, C-terminal)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR014790(MutL, C-terminal, dimerisation)|interpro:IPR020568|interpro:IPR028830|interpro:IPR036890|interpro:IPR037198|interpro:IPR038973|interpro:IPR042120|rcsb pdb:6RMN|rcsb pdb:6SHX|rcsb pdb:6SNS|rcsb pdb:6SNV|sgd:YPL164C(identity)	refseq:NP_004413.1|ensembl:ENSG00000004975(gene)|ensembl:ENST00000005340(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005109"(frizzled binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0007507"(heart development)|go:"GO:0016235"(aggresome)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044340"(canonical Wnt signaling pathway involved in regulation of cell proliferation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0150012"(positive regulation of neuron projection arborization)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008341(Dishevelled-2 region)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:O14641|rcsb pdb:2REY|rcsb pdb:3CBX|rcsb pdb:3CBY|rcsb pdb:3CBZ|rcsb pdb:3CC0|rcsb pdb:4WIP|rcsb pdb:5LNP|rcsb pdb:5SUY|rcsb pdb:5SUZ|rcsb pdb:6IW3|rcsb pdb:6JCK|reactome:R-HSA-201681|reactome:R-HSA-201688|reactome:R-HSA-2028269|reactome:R-HSA-4086400|reactome:R-HSA-4608870|reactome:R-HSA-4641258|reactome:R-HSA-4641262|reactome:R-HSA-5099900|reactome:R-HSA-5368598|reactome:R-HSA-5663220|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9673324|ensembl:ENSP00000005340|dip:DIP-34433N|entrezgene/locuslink:1856(identity)	-	crc64:970FD7F57EB6E3B1	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:g47/5yM9oWZ13CIZOZ7QT6A+LW0559292	rogid:2Vdc8oRnT4Mz/j+EXQXrL3AszOc9606	intact-crc:227BFC6332823A34|rigid:16ES/w009LWem2L7ONdWO8+tzbA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96BA8	uniprotkb:Q12078	intact:EBI-6942903|ensembl:ENSP00000481956|intact:MINT-268046|intact:MINT-8162577|uniprotkb:Q8N2D5|uniprotkb:Q96CP0	intact:EBI-37834|uniprotkb:D6VY36|ensemblfungi:YLR034C	psi-mi:cr3l1_human(display_long)|uniprotkb:CREB3L1(gene name)|psi-mi:CREB3L1(display_short)|uniprotkb:OASIS(gene name synonym)|uniprotkb:PSEC0238(orf name)|uniprotkb:Old astrocyte specifically-induced substance(gene name synonym)	psi-mi:smf3_yeast(display_long)|uniprotkb:SMF3(gene name)|psi-mi:SMF3(display_short)|uniprotkb:YLR034C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11546952|imex:IM-24995-2598	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157613(gene)|ensembl:ENST00000621158(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0070278"(extracellular matrix constituent secretion)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029805|mint:Q96BA8|reactome:R-HSA-8874211|refseq:NP_443086.1|entrezgene/locuslink:90993(identity)	refseq:NP_013134.1|sgd:S000004024|dip:DIP-4163N|mint:Q12078|ensemblfungi:YLR034C(gene)|ensemblfungi:YLR034C_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005384"(manganese ion transmembrane transporter activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006826"(iron ion transport)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0015086"(cadmium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022890"(inorganic cation transmembrane transporter activity)|go:"GO:0030026"(cellular manganese ion homeostasis)|go:"GO:0046872"(metal ion binding)|interpro:IPR001046(Natural resistance-associated macrophage protein)|sgd:YLR034C(identity)	-	comment:mint|function:"Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE"	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:sMWUFmBeBBCO+T0Y2CuB/un1lBg9606	rogid:H499EDh2oumEUzbjjW4GvAiVFBo559292	intact-crc:B9975DB20D74A770|rigid:YWJmXxkxAkKRFYGR/c+7lgsFwuo	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12071	uniprotkb:Q9H6J7-4	intact:EBI-36751|uniprotkb:D6VS12|ensemblfungi:YDR027C	intact:EBI-11536490|ensembl:ENSP00000367881	psi-mi:vps54_yeast(display_long)|uniprotkb:VPS54(gene name)|psi-mi:VPS54(display_short)|uniprotkb:CGP1(gene name synonym)|uniprotkb:CPF1 genetically-interacting protein 1(gene name synonym)|uniprotkb:Temperature-sensitive clathrin synthetic mutation protein 3(gene name synonym)|uniprotkb:LUV1(gene name synonym)|uniprotkb:RKI1(gene name synonym)|uniprotkb:TCS3(gene name synonym)|uniprotkb:YDR027C(locus name)|uniprotkb:PZF889(orf name)|uniprotkb:YD9813.05C(orf name)	psi-mi:q9h6j7-4(display_long)|uniprotkb:C11orf49(gene name)|psi-mi:C11orf49(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11546941|imex:IM-24995-2597	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010310.1|sgd:S000002434|mint:Q12071|dip:DIP-5903N|ensemblfungi:YDR027C(gene)|ensemblfungi:YDR027C_mRNA(transcript)|go:"GO:0000938"(GARP complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030476"(ascospore wall assembly)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0090156"(cellular sphingolipid homeostasis)|interpro:IPR039745|sgd:YDR027C(identity)	intact:EBI-721300(isoform-parent)|ensembl:ENSG00000149179(gene)|ensembl:ENST00000378618(transcript)|entrezgene/locuslink:79096(identity)	-	-	isoform-comment:No experimental confirmation available.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:zouXMNMGbIJwjId/O7zsCZccY90559292	rogid:IXWzzwfToJyIlZmm7FsAk7WFslY9606	intact-crc:E549B113EB0E77E5|rigid:QA97QFpcKzHeViAEcPx06mRXIoQ	false	-	sufficient binding region:1-274	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12056	uniprotkb:Q9UJV3-2	intact:EBI-30488|uniprotkb:D6W2T0|ensemblfungi:YOR226C	intact:EBI-10172526|ensembl:ENSP00000413976	psi-mi:isu2_yeast(display_long)|uniprotkb:Iron sulfur cluster scaffold protein 2(gene name synonym)|uniprotkb:ISU2(gene name)|psi-mi:ISU2(display_short)|uniprotkb:NUA2(gene name synonym)|uniprotkb:YOR226C(locus name)	psi-mi:q9ujv3-2(display_long)|uniprotkb:RING-type E3 ubiquitin transferase MID2(gene name synonym)|uniprotkb:FXY2(gene name synonym)|uniprotkb:Midin-2(gene name synonym)|uniprotkb:Midline defect 2(gene name synonym)|uniprotkb:Midline-2(gene name synonym)|uniprotkb:RING finger protein 60(gene name synonym)|uniprotkb:RNF60(gene name synonym)|uniprotkb:TRIM1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 1(gene name synonym)|uniprotkb:MID2(gene name)|psi-mi:MID2(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11546930|imex:IM-24995-2596	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005752|refseq:NP_014869.3|dip:DIP-4123N|ensemblfungi:YOR226C(gene)|ensemblfungi:YOR226C_mRNA(transcript)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005737"(cytoplasm)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR002871(NIF system FeS cluster assembly, NifU, N-terminal)|interpro:IPR011339(ISC system FeS cluster assembly, IscU scaffold)|sgd:YOR226C(identity)	intact:EBI-751983(isoform-parent)|uniprotkb:Q9UJV3-2(isoform-parent)|ensembl:ENSG00000080561(gene)|ensembl:ENST00000443968(transcript)|entrezgene/locuslink:11043(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:e4qx7ic8wpO6cTHGl73je/JVzMY559292	rogid:/FJ+V2H7SaWon7caUWkEkmHFVxQ9606	intact-crc:7BCD1A2371AD99D5|rigid:AvoXwGtX3clmjr6s4MtRim19PzA	false	-	sufficient binding region:21-705	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UJC3	uniprotkb:Q12056	intact:EBI-746704|uniprotkb:O60561|uniprotkb:Q5TG44|uniprotkb:A8MU44|uniprotkb:B4DX15|uniprotkb:A8K8E9|intact:EBI-10969618|ensembl:ENSP00000360252	intact:EBI-30488|uniprotkb:D6W2T0|ensemblfungi:YOR226C	psi-mi:hook1_human(display_long)|uniprotkb:HOOK1(gene name)|psi-mi:HOOK1(display_short)	psi-mi:isu2_yeast(display_long)|uniprotkb:Iron sulfur cluster scaffold protein 2(gene name synonym)|uniprotkb:ISU2(gene name)|psi-mi:ISU2(display_short)|uniprotkb:NUA2(gene name synonym)|uniprotkb:YOR226C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11546921|imex:IM-24995-2595	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_056972.1|ensembl:ENSG00000134709(gene)|ensembl:ENST00000371208(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0007030"(Golgi organization)|go:"GO:0007032"(endosome organization)|go:"GO:0007040"(lysosome organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0015031"(protein transport)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0051959"(dynein light intermediate chain binding)|go:"GO:0070695"(FHF complex)|go:"GO:1905198"(manchette assembly)|go:"GO:1905719"(protein localization to perinuclear region of cytoplasm)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR008636(HOOK)|interpro:IPR036872|interpro:IPR043936|mint:Q9UJC3|entrezgene/locuslink:51361(identity)	sgd:S000005752|refseq:NP_014869.3|dip:DIP-4123N|ensemblfungi:YOR226C(gene)|ensemblfungi:YOR226C_mRNA(transcript)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005737"(cytoplasm)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR002871(NIF system FeS cluster assembly, NifU, N-terminal)|interpro:IPR011339(ISC system FeS cluster assembly, IscU scaffold)|sgd:YOR226C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:QOcYbuKfnNIlNKzos5v+0+A2h3I9606	rogid:e4qx7ic8wpO6cTHGl73je/JVzMY559292	intact-crc:BC6563CA3DCEF20C|rigid:gr7ksJ1UTUAWMb+nNZCp/sOdtA0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12056	uniprotkb:Q5JR59-3	intact:EBI-30488|uniprotkb:D6W2T0|ensemblfungi:YOR226C	intact:EBI-11522433|ensembl:ENSP00000370186	psi-mi:isu2_yeast(display_long)|uniprotkb:Iron sulfur cluster scaffold protein 2(gene name synonym)|uniprotkb:ISU2(gene name)|psi-mi:ISU2(display_short)|uniprotkb:NUA2(gene name synonym)|uniprotkb:YOR226C(locus name)	psi-mi:q5jr59-3(display_long)|uniprotkb:MTUS2(gene name)|psi-mi:MTUS2(display_short)|uniprotkb:CAZIP(gene name synonym)|uniprotkb:Cardiac zipper protein(gene name synonym)|uniprotkb:KIAA0774(gene name synonym)|uniprotkb:Microtubule plus-end tracking protein TIP150(gene name synonym)|uniprotkb:TIP150(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11546912|imex:IM-24995-2594	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005752|refseq:NP_014869.3|dip:DIP-4123N|ensemblfungi:YOR226C(gene)|ensemblfungi:YOR226C_mRNA(transcript)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005737"(cytoplasm)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR002871(NIF system FeS cluster assembly, NifU, N-terminal)|interpro:IPR011339(ISC system FeS cluster assembly, IscU scaffold)|sgd:YOR226C(identity)	ensembl:ENSG00000132938(gene)|ensembl:ENST00000380808(transcript)|intact:EBI-742948(isoform-parent)|uniprotkb:Q5JR59-3(isoform-parent)|entrezgene/locuslink:23281(identity)	-	-	isoform-comment:No experimental confirmation available.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:e4qx7ic8wpO6cTHGl73je/JVzMY559292	rogid:npId9tC7VoLN/jteoBiRbSYChPs9606	intact-crc:5B886A4BF4CF8C59|rigid:ib6N2MWFX4QO5wg3LquH2AFjOl0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P00492	uniprotkb:Q12056	intact:EBI-748210|uniprotkb:A6NHF0|uniprotkb:B2R8M9|ensembl:ENSP00000298556	intact:EBI-30488|uniprotkb:D6W2T0|ensemblfungi:YOR226C	psi-mi:hprt_human(display_long)|uniprotkb:HPRT1(gene name)|psi-mi:HPRT1(display_short)|uniprotkb:HPRT(gene name synonym)	psi-mi:isu2_yeast(display_long)|uniprotkb:Iron sulfur cluster scaffold protein 2(gene name synonym)|uniprotkb:ISU2(gene name)|psi-mi:ISU2(display_short)|uniprotkb:NUA2(gene name synonym)|uniprotkb:YOR226C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11546903|imex:IM-24995-2593	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000185.1|ensembl:ENSG00000165704(gene)|ensembl:ENST00000298556(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001913"(T cell mediated cytotoxicity)|go:"GO:0001975"(response to amphetamine)|go:"GO:0004422"(hypoxanthine phosphoribosyltransferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006164"(purine nucleotide biosynthetic process)|go:"GO:0006166"(purine ribonucleoside salvage)|go:"GO:0006168"(adenine salvage)|go:"GO:0006178"(guanine salvage)|go:"GO:0007625"(grooming behavior)|go:"GO:0007626"(locomotory behavior)|go:"GO:0021756"(striatum development)|go:"GO:0021895"(cerebral cortex neuron differentiation)|go:"GO:0021954"(central nervous system neuron development)|go:"GO:0032263"(GMP salvage)|go:"GO:0032264"(IMP salvage)|go:"GO:0042417"(dopamine metabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043103"(hypoxanthine salvage)|go:"GO:0045964"(positive regulation of dopamine metabolic process)|go:"GO:0046038"(GMP catabolic process)|go:"GO:0046040"(IMP metabolic process)|go:"GO:0046100"(hypoxanthine metabolic process)|go:"GO:0046651"(lymphocyte proliferation)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0052657"(guanine phosphoribosyltransferase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000836(Phosphoribosyltransferase)|interpro:IPR005904(Hypoxanthine phosphoribosyl transferase)|interpro:IPR029057|mint:P00492|rcsb pdb:1BZY|rcsb pdb:1D6N|rcsb pdb:1HMP|rcsb pdb:1Z7G|go:"GO:0048813"(dendrite morphogenesis)|rcsb pdb:2VFA|rcsb pdb:3GEP|rcsb pdb:3GGC|rcsb pdb:3GGJ|rcsb pdb:4IJQ|rcsb pdb:4KN6|rcsb pdb:4RAB|rcsb pdb:4RAC|rcsb pdb:4RAD|rcsb pdb:4RAN|rcsb pdb:4RAO|rcsb pdb:4RAQ|rcsb pdb:5BRN|rcsb pdb:5BSK|rcsb pdb:5HIA|rcsb pdb:5W8V|rcsb pdb:6BNJ|reactome:R-HSA-74217|entrezgene/locuslink:3251(identity)	sgd:S000005752|refseq:NP_014869.3|dip:DIP-4123N|ensemblfungi:YOR226C(gene)|ensemblfungi:YOR226C_mRNA(transcript)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005737"(cytoplasm)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR002871(NIF system FeS cluster assembly, NifU, N-terminal)|interpro:IPR011339(ISC system FeS cluster assembly, IscU scaffold)|sgd:YOR226C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:w87Sv/qOAkHFqJm0vu0Ayqlz7TA9606	rogid:e4qx7ic8wpO6cTHGl73je/JVzMY559292	intact-crc:B6DCC93F4D908F19|rigid:Lpr9k6sEcTlx/vkByavYO7/5wLg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12154	uniprotkb:O43852-3	intact:EBI-2989|uniprotkb:Q6B1B6|uniprotkb:D6VRQ0|ensemblfungi:YDL100C	intact:EBI-11536607|ensembl:ENSP00000420381	psi-mi:get3_yeast(display_long)|uniprotkb:YDL100C(locus name)|uniprotkb:GET3(gene name)|psi-mi:GET3(display_short)|uniprotkb:ARR4(gene name synonym)|uniprotkb:D2371(orf name)|uniprotkb:Arsenical pump-driving ATPase(gene name synonym)|uniprotkb:Arsenite-stimulated ATPase(gene name synonym)|uniprotkb:Guided entry of tail-anchored proteins 3(gene name synonym)|uniprotkb:Golgi to ER traffic protein 3(gene name synonym)	psi-mi:o43852-3(display_long)|uniprotkb:CALU(gene name)|psi-mi:CALU(display_short)|uniprotkb:Crocalbin(gene name synonym)|uniprotkb:IEF SSP 9302(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11547051|imex:IM-24995-2609	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010183.1|sgd:S000002258|dip:DIP-3908N|mint:Q12154|ensemblfungi:YDL100C(gene)|ensemblfungi:YDL100C_mRNA(transcript)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0009408"(response to heat)|go:"GO:0010038"(response to metal ion)|go:"GO:0016787"(hydrolase activity)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043529"(GET complex)|go:"GO:0045048"(protein insertion into ER membrane)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0046872"(metal ion binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:1990507"(obsolete ATP-independent chaperone mediated protein folding)|interpro:IPR016300(Arsenite-transporting ATPase)|interpro:IPR025723|interpro:IPR027417|interpro:IPR027542|rcsb pdb:2WOJ|rcsb pdb:3A36|rcsb pdb:3A37|rcsb pdb:3B2E|rcsb pdb:3H84|rcsb pdb:3IDQ|rcsb pdb:3SJA|rcsb pdb:3SJB|rcsb pdb:3SJC|rcsb pdb:3SJD|rcsb pdb:3VLC|rcsb pdb:3ZS8|rcsb pdb:3ZS9|rcsb pdb:4PWX|rcsb pdb:4XTR|rcsb pdb:4XVU|rcsb pdb:4XWO|rcsb pdb:5BW8|rcsb pdb:5BWK|sgd:YDL100C(identity)	intact:EBI-1171069(isoform-parent)|ensembl:ENSG00000128595(gene)|ensembl:ENST00000479257(transcript)|uniprotkb:O43852-3(isoform-parent)|entrezgene/locuslink:813(identity)	-	crc64:F795C359B5A4A461	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Y+PTDg+beVeCH5mn4BvWi5wBP4A559292	rogid:aOndJVrdQPKMOgVAthD1hiWG67I9606	intact-crc:3558588D063C0FCD|rigid:GvPIIbD+WC8wfweB85M2uc9EhGA	false	-	sufficient binding region:9-323	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O95994	uniprotkb:Q12140	intact:EBI-712648|ensembl:ENSP00000391490	intact:EBI-36401|uniprotkb:D6VRV7|ensemblfungi:YDL037C	psi-mi:agr2_human(display_long)|uniprotkb:Secreted cement gland protein XAG-2 homolog(gene name synonym)|uniprotkb:HPC8(gene name synonym)|uniprotkb:AG2(gene name synonym)|uniprotkb:UNQ515/PRO1030(orf name)|uniprotkb:AGR2(gene name)|psi-mi:AGR2(display_short)	psi-mi:bsc1_yeast(display_long)|uniprotkb:BSC1(gene name)|psi-mi:BSC1(display_short)|uniprotkb:D2734(orf name)|uniprotkb:YDL037C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11547042|imex:IM-24995-2608	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005615"(extracellular space)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0042802"(identical protein binding)|go:"GO:0045742"(positive regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0048546"(digestive tract morphogenesis)|go:"GO:0048639"(positive regulation of developmental growth)|go:"GO:0060480"(lung goblet cell differentiation)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070254"(mucus secretion)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:1903896"(positive regulation of IRE1-mediated unfolded protein response)|go:"GO:1903899"(positive regulation of PERK-mediated unfolded protein response)|interpro:IPR036249|rcsb pdb:2LNS|rcsb pdb:2LNT|ensembl:ENSG00000106541(gene)|ensembl:ENST00000419304(transcript)|go:"GO:0002162"(dystroglycan binding)|go:"GO:0005154"(epidermal growth factor receptor binding)|refseq:NP_006399.1|refseq:XP_005249638.1|dip:DIP-48825N|entrezgene/locuslink:10551(identity)	sgd:S000002195|refseq:NP_010247.1|mint:Q12140|dip:DIP-5600N|ensemblfungi:YDL037C(gene)|ensemblfungi:YDL037C_mRNA(transcript)|interpro:IPR018789|sgd:YDL037C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:E824a1MDXuGzk23ohjS7HAeEx5U9606	rogid:SmUACU6i/VlGLn/aQLehbLRAWjg559292	intact-crc:D77D41F6AC016F73|rigid:4FQbXEZpmcQEmuFAbCM/QPhhQOs	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12140	uniprotkb:O15294-3	intact:EBI-36401|uniprotkb:D6VRV7|ensemblfungi:YDL037C	intact:EBI-11536584|ensembl:ENSP00000362805	psi-mi:bsc1_yeast(display_long)|uniprotkb:BSC1(gene name)|psi-mi:BSC1(display_short)|uniprotkb:D2734(orf name)|uniprotkb:YDL037C(locus name)	psi-mi:o15294-3(display_long)|uniprotkb:O-GlcNAc transferase subunit p110(gene name synonym)|uniprotkb:O-linked N-acetylglucosamine transferase 110 kDa subunit(gene name synonym)|uniprotkb:OGT(gene name)|psi-mi:OGT(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11547033|imex:IM-24995-2607	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002195|refseq:NP_010247.1|mint:Q12140|dip:DIP-5600N|ensemblfungi:YDL037C(gene)|ensemblfungi:YDL037C_mRNA(transcript)|interpro:IPR018789|sgd:YDL037C(identity)	ensembl:ENSG00000147162(gene)|ensembl:ENST00000373701(transcript)|intact:EBI-539828(isoform-parent)|uniprotkb:O15294-3(isoform-parent)|entrezgene/locuslink:8473(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:SmUACU6i/VlGLn/aQLehbLRAWjg559292	rogid:tD46KhQ2nrCEOBxms28dL2gQjFQ9606	intact-crc:A2BF6BC91F0E6155|rigid:4/hnLIUJAiygqxxyJvMKyADo424	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12134	uniprotkb:Q9H190	intact:EBI-37262|uniprotkb:D6W2Y2|ensemblfungi:YOR284W	intact:EBI-742426|ensembl:ENSP00000371233|uniprotkb:O95892|uniprotkb:Q5W0X1|uniprotkb:Q9BZ42|uniprotkb:Q9H567|uniprotkb:Q9NRY8|intact:EBI-28983470|ensembl:ENSP00000342935|ensembl:ENSP00000354013	psi-mi:hua2_yeast(display_long)|uniprotkb:HUA2(gene name)|psi-mi:HUA2(display_short)|uniprotkb:YOR284W(locus name)	psi-mi:sdcb2_human(display_long)|uniprotkb:Similar to TACIP18(gene name synonym)|uniprotkb:SDCBP2(gene name)|psi-mi:SDCBP2(display_short)|uniprotkb:SITAC18(gene name synonym)|uniprotkb:Syndecan-binding protein 2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11547024|imex:IM-24995-2606	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005810|refseq:NP_014927.3|dip:DIP-1472N|ensemblfungi:YOR284W(gene)|ensemblfungi:YOR284W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|sgd:YOR284W(identity)	refseq:NP_001186713.1|refseq:NP_056500.2|refseq:NP_536737.3|ensembl:ENSP00000342935|ensembl:ENSP00000354013|ensembl:ENST00000381808|ensembl:ENSP00000371229|ensembl:ENSP00000371233|ensembl:ENSG00000125775(gene)|ensembl:ENST00000360779(transcript)|ensembl:ENST00000381812(transcript)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007399"(nervous system development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016607"(nuclear speck)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046907"(intracellular transport)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036034|interpro:IPR041489|ensembl:ENST00000339987(transcript)|entrezgene/locuslink:27111(identity)	-	crc64:B1F3A81B7C0F65AC	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:1pZZ+nqYY1Ah7Zdeu4QP4kvKfsw559292	rogid:vlEtVZkwLTte5PJ4i8ce+SwE/4Y9606	intact-crc:E3AD5315104DBCF9|rigid:4ghmKfu8fA2mV/jIaTlq1waDxbs	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12134	uniprotkb:O14641	intact:EBI-37262|uniprotkb:D6W2Y2|ensemblfungi:YOR284W	intact:EBI-740850|ensembl:ENSP00000005340|uniprotkb:Q53XM0|uniprotkb:D3DTN3	psi-mi:hua2_yeast(display_long)|uniprotkb:HUA2(gene name)|psi-mi:HUA2(display_short)|uniprotkb:YOR284W(locus name)	psi-mi:dvl2_human(display_long)|uniprotkb:DSH homolog 2(gene name synonym)|uniprotkb:DVL2(gene name)|psi-mi:DVL2(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11547015|imex:IM-24995-2605	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005810|refseq:NP_014927.3|dip:DIP-1472N|ensemblfungi:YOR284W(gene)|ensemblfungi:YOR284W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|sgd:YOR284W(identity)	refseq:NP_004413.1|ensembl:ENSG00000004975(gene)|ensembl:ENST00000005340(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005109"(frizzled binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0007507"(heart development)|go:"GO:0016235"(aggresome)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044340"(canonical Wnt signaling pathway involved in regulation of cell proliferation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0150012"(positive regulation of neuron projection arborization)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008341(Dishevelled-2 region)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:O14641|rcsb pdb:2REY|rcsb pdb:3CBX|rcsb pdb:3CBY|rcsb pdb:3CBZ|rcsb pdb:3CC0|rcsb pdb:4WIP|rcsb pdb:5LNP|rcsb pdb:5SUY|rcsb pdb:5SUZ|rcsb pdb:6IW3|rcsb pdb:6JCK|reactome:R-HSA-201681|reactome:R-HSA-201688|reactome:R-HSA-2028269|reactome:R-HSA-4086400|reactome:R-HSA-4608870|reactome:R-HSA-4641258|reactome:R-HSA-4641262|reactome:R-HSA-5099900|reactome:R-HSA-5368598|reactome:R-HSA-5663220|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9673324|ensembl:ENSP00000005340|dip:DIP-34433N|entrezgene/locuslink:1856(identity)	-	crc64:B1F3A81B7C0F65AC	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:1pZZ+nqYY1Ah7Zdeu4QP4kvKfsw559292	rogid:2Vdc8oRnT4Mz/j+EXQXrL3AszOc9606	intact-crc:3F0B5DA85AE42BC5|rigid:5PUN737MJ7ucAP8Bhs3yLOLJQ6M	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12118	uniprotkb:Q8N6L0	intact:EBI-31784|uniprotkb:D6W273|ensemblfungi:YOR007C	intact:EBI-749265|uniprotkb:Q96MC3|ensembl:ENSP00000404220	psi-mi:sgt2_yeast(display_long)|uniprotkb:Viral protein U-binding protein(gene name synonym)|uniprotkb:SGT/UBP(gene name synonym)|uniprotkb:SGT2(gene name)|psi-mi:SGT2(display_short)|uniprotkb:UNF346(orf name)|uniprotkb:YOR007C(locus name)	psi-mi:kash5_human(display_long)|uniprotkb:KASH5(gene name)|psi-mi:KASH5(display_short)|uniprotkb:CCDC155(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 155(gene name synonym)|uniprotkb:KASH domain-containing protein 5(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11547006|imex:IM-24995-2604	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014649.1|sgd:S000005533|dip:DIP-1983N|mint:Q12118|ensemblfungi:YOR007C(gene)|ensemblfungi:YOR007C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0009408"(response to heat)|go:"GO:0016020"(membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0072380"(TRC complex)|go:"GO:1903646"(positive regulation of chaperone-mediated protein folding)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR032374|rcsb pdb:2LXB|rcsb pdb:2LXC|rcsb pdb:3ZDM|rcsb pdb:4ASV|rcsb pdb:4ASW|rcsb pdb:5LYN|rcsb pdb:5LYP|reactome:R-SCE-9609523|sgd:YOR007C(identity)	refseq:NP_653289.3|ensembl:ENSG00000161609(gene)|ensembl:ENST00000447857(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034397"(telomere localization)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051225"(spindle assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0090172"(microtubule cytoskeleton organization involved in homologous chromosome segregation)|go:"GO:0090220"(chromosome localization to nuclear envelope involved in homologous chromosome segregation)|go:"GO:0090619"(meiotic spindle pole)|interpro:IPR011992(EF-Hand type)|interpro:IPR028168|interpro:IPR028170|interpro:IPR039508|mint:Q8N6L0|rcsb pdb:6R2I|rcsb pdb:6WMF|entrezgene/locuslink:147872(identity)	-	crc64:33539B74F742BD3C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:u4qztYWJIAVQOzZGnkLFnO3S2NA559292	rogid:Wl9L7AcvDHCZuKjYLn8QgGIbZTc9606	intact-crc:1FB35102E6C901D1|rigid:oOlfY2RAvw3VKWEdOMZwnytHY8o	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O95994	uniprotkb:Q12118	intact:EBI-712648|ensembl:ENSP00000391490	intact:EBI-31784|uniprotkb:D6W273|ensemblfungi:YOR007C	psi-mi:agr2_human(display_long)|uniprotkb:Secreted cement gland protein XAG-2 homolog(gene name synonym)|uniprotkb:HPC8(gene name synonym)|uniprotkb:AG2(gene name synonym)|uniprotkb:UNQ515/PRO1030(orf name)|uniprotkb:AGR2(gene name)|psi-mi:AGR2(display_short)	psi-mi:sgt2_yeast(display_long)|uniprotkb:Viral protein U-binding protein(gene name synonym)|uniprotkb:SGT/UBP(gene name synonym)|uniprotkb:SGT2(gene name)|psi-mi:SGT2(display_short)|uniprotkb:UNF346(orf name)|uniprotkb:YOR007C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11546997|imex:IM-24995-2603	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005615"(extracellular space)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0042802"(identical protein binding)|go:"GO:0045742"(positive regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0048546"(digestive tract morphogenesis)|go:"GO:0048639"(positive regulation of developmental growth)|go:"GO:0060480"(lung goblet cell differentiation)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070254"(mucus secretion)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:1903896"(positive regulation of IRE1-mediated unfolded protein response)|go:"GO:1903899"(positive regulation of PERK-mediated unfolded protein response)|interpro:IPR036249|rcsb pdb:2LNS|rcsb pdb:2LNT|ensembl:ENSG00000106541(gene)|ensembl:ENST00000419304(transcript)|go:"GO:0002162"(dystroglycan binding)|go:"GO:0005154"(epidermal growth factor receptor binding)|refseq:NP_006399.1|refseq:XP_005249638.1|dip:DIP-48825N|entrezgene/locuslink:10551(identity)	refseq:NP_014649.1|sgd:S000005533|dip:DIP-1983N|mint:Q12118|ensemblfungi:YOR007C(gene)|ensemblfungi:YOR007C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0009408"(response to heat)|go:"GO:0016020"(membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0072380"(TRC complex)|go:"GO:1903646"(positive regulation of chaperone-mediated protein folding)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR032374|rcsb pdb:2LXB|rcsb pdb:2LXC|rcsb pdb:3ZDM|rcsb pdb:4ASV|rcsb pdb:4ASW|rcsb pdb:5LYN|rcsb pdb:5LYP|reactome:R-SCE-9609523|sgd:YOR007C(identity)	-	-	crc64:33539B74F742BD3C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:E824a1MDXuGzk23ohjS7HAeEx5U9606	rogid:u4qztYWJIAVQOzZGnkLFnO3S2NA559292	intact-crc:71FEF381CE0C4225|rigid:xaz+7kRyJHFYlSLNGF+ccJsj5sc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9BYV6-2	uniprotkb:Q12100	intact:EBI-11522718|ensembl:ENSP00000297348	intact:EBI-36072|uniprotkb:D6VRW6|ensemblfungi:YDL025C	psi-mi:q9byv6-2(display_long)|uniprotkb:TRIM55(gene name)|psi-mi:TRIM55(display_short)|uniprotkb:MURF2(gene name synonym)|uniprotkb:Muscle-specific RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 29(gene name synonym)|uniprotkb:RNF29(gene name synonym)|uniprotkb:p50(isoform synonym)	psi-mi:rtk1_yeast(display_long)|uniprotkb:YDL025C(locus name)|uniprotkb:D2810(orf name)|uniprotkb:RTK1(gene name)|psi-mi:RTK1(display_short)|uniprotkb:Ribosome biogenesis and tRNA synthetase-associated kinase 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11546988|imex:IM-24995-2602	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-2341179(isoform-parent)|uniprotkb:Q9BYV6-2(isoform-parent)|ensembl:ENSG00000147573(gene)|ensembl:ENST00000353317(transcript)|entrezgene/locuslink:84675(identity)	refseq:NP_010259.1|sgd:S000002183|dip:DIP-6483N|ensemblfungi:YDL025C(gene)|ensemblfungi:YDL025C_mRNA(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0071944"(cell periphery)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|sgd:YDL025C(identity)	-	-	crc64:AD6160F19F3B75CF	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:9t8UhK+Z1yBqjnQrOqPD76NuXGg9606	rogid:XBcHXpXSRZDscEoj+hGRn4NJORE559292	intact-crc:90135950B01BAE73|rigid:qG6u9WnJpwZk5+NacyJyKRqP1tg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:E9PFK9	uniprotkb:Q12161	intact:EBI-11523104|ensembl:ENSP00000403429	intact:EBI-34372|uniprotkb:D6W213|ensemblfungi:YOL054W	psi-mi:e9pfk9_human(display_long)|uniprotkb:RABGEF1(gene name)|psi-mi:RABGEF1(display_short)	psi-mi:psh1_yeast(display_long)|uniprotkb:PSH1(gene name)|psi-mi:PSH1(display_short)|uniprotkb:POB3/SPT16 histone-associated protein 1(gene name synonym)|uniprotkb:O1263(orf name)|uniprotkb:YOL054W(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11547111|imex:IM-24995-2615	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000154710(gene)|ensembl:ENST00000439720(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|interpro:IPR002653(Zinc finger, A20-type)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR037191|interpro:IPR041545|entrezgene/locuslink:27342(identity)	refseq:NP_014587.1|sgd:S000005415|mint:Q12161|dip:DIP-6481N|ensemblfungi:YOL054W(gene)|ensemblfungi:YOL054W_mRNA(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|sgd:YOL054W(identity)	-	-	crc64:CE0ECBCB6D465554	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:JDHW8cuCB2z39j6a+LlkARnLfYo9606	rogid:AvPMRd/GjfaTyQjEfMPhBVcvOs4559292	intact-crc:D29B9FB39CE9FF56|rigid:TsRHWiVq3l/wIp27zh63pFUpDhc	false	sufficient binding region:14-504	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12161	uniprotkb:Q8N5R6	intact:EBI-34372|uniprotkb:D6W213|ensemblfungi:YOL054W	intact:EBI-740841|intact:EBI-953781|uniprotkb:B3KQ49|uniprotkb:A8K3U4|uniprotkb:A8MPQ6|uniprotkb:A8MV61|uniprotkb:A8MVU9|uniprotkb:Q9H5Q6|uniprotkb:Q8TAX6|intact:EBI-2320546|intact:EBI-11522976	psi-mi:psh1_yeast(display_long)|uniprotkb:PSH1(gene name)|psi-mi:PSH1(display_short)|uniprotkb:POB3/SPT16 histone-associated protein 1(gene name synonym)|uniprotkb:O1263(orf name)|uniprotkb:YOL054W(locus name)	psi-mi:ccd33_human(display_long)|uniprotkb:CCDC33(gene name)|psi-mi:CCDC33(display_short)|uniprotkb:Cancer/testis antigen 61(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11547102|imex:IM-24995-2614	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014587.1|sgd:S000005415|mint:Q12161|dip:DIP-6481N|ensemblfungi:YOL054W(gene)|ensemblfungi:YOL054W_mRNA(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|sgd:YOL054W(identity)	refseq:NP_079331.3|interpro:IPR000008(C2 calcium-dependent membrane targeting)|go:"GO:0005777"(peroxisome)|refseq:NP_001274110.1|refseq:NP_877592.2|mint:Q8N5R6|interpro:IPR035892|interpro:IPR039889|entrezgene/locuslink:80125(identity)	-	crc64:CE0ECBCB6D465554	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2021/11/30	rogid:AvPMRd/GjfaTyQjEfMPhBVcvOs4559292	rogid:eEIn7pQyfdHWx8TeLJpYy0i/gww9606	intact-crc:69F64A6E82A3113D|rigid:aXopAJOgoLUSDTx6zmifwQ79GHA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q13164	uniprotkb:Q12156	intact:EBI-1213983|uniprotkb:Q16634|uniprotkb:Q59F50|uniprotkb:Q6QLU7|uniprotkb:Q7L4P4|uniprotkb:Q969G1|uniprotkb:Q96G51|intact:EBI-28979986|ensembl:ENSP00000311005|ensembl:ENSP00000378966|ensembl:ENSP00000378968	intact:EBI-30371|uniprotkb:D6VS49|ensemblfungi:YDR063W	psi-mi:mk07_human(display_long)|uniprotkb:MAPK7(gene name)|psi-mi:MAPK7(display_short)|uniprotkb:BMK1(gene name synonym)|uniprotkb:ERK5(gene name synonym)|uniprotkb:PRKM7(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 5(gene name synonym)|uniprotkb:Big MAP kinase 1(gene name synonym)	psi-mi:aim7_yeast(display_long)|uniprotkb:AIM7(gene name)|psi-mi:AIM7(display_short)|uniprotkb:D4245(orf name)|uniprotkb:YDR063W(locus name)|uniprotkb:Altered inheritance rate of mitochondria protein 7(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11547091|imex:IM-24995-2613	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002740.2|refseq:NP_620601.1|refseq:NP_620602.2|refseq:NP_620603.2|ensembl:ENST00000299612|ensembl:ENSP00000299612|ensembl:ENSP00000311005|ensembl:ENSP00000378966|ensembl:ENSP00000378968|refseq:XP_011522259.1|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0036003"(positive regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0051019"(mitogen-activated protein kinase binding)|go:"GO:0051247"(positive regulation of protein metabolic process)|go:"GO:0051344"(negative regulation of cyclic-nucleotide phosphodiesterase activity)|go:"GO:0060761"(negative regulation of response to cytokine stimulus)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071499"(cellular response to laminar fluid shear stress)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1902176"(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:2000352"(negative regulation of endothelial cell apoptotic process)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q13164|rcsb pdb:2Q8Y|rcsb pdb:4B99|rcsb pdb:4IC7|rcsb pdb:4IC8|rcsb pdb:4ZSG|rcsb pdb:4ZSJ|rcsb pdb:4ZSL|rcsb pdb:5BYY|rcsb pdb:5BYZ|rcsb pdb:5O7I|rcsb pdb:6HKM|rcsb pdb:6HKN|reactome:R-HSA-198753|reactome:R-HSA-198765|reactome:R-HSA-202670|reactome:R-HSA-2559582|reactome:R-HSA-881907|reactome:R-HSA-8853659|ensembl:ENSG00000166484(gene)|ensembl:ENST00000308406(transcript)|ensembl:ENST00000395602(transcript)|ensembl:ENST00000395604(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0016605"(PML body)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0030154"(cell differentiation)|go:"GO:0034115"(negative regulation of heterotypic cell-cell adhesion)|entrezgene/locuslink:5598(identity)	refseq:NP_010348.1|sgd:S000002470|dip:DIP-1818N|mint:Q12156|ensemblfungi:YDR063W(gene)|ensemblfungi:YDR063W_mRNA(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0030479"(actin cortical patch)|go:"GO:0034316"(negative regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0071846"(actin filament debranching)|go:"GO:0071933"(Arp2/3 complex binding)|interpro:IPR002108(Actin-binding, cofilin/tropomyosin type)|interpro:IPR011171(Glia maturation factor beta)|interpro:IPR029006|reactome:R-SCE-6798695|sgd:YDR063W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:dUTMnlgdjEkFhq0i6RmvpX5U7BM9606	rogid:gNpFPaIObSMCgvbNabMJOjJMjco559292	intact-crc:7DFEC09086473446|rigid:u53oTcdp6xI5CMxJ6KZDXnSo5HE	false	sufficient binding region:140-816	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12154	uniprotkb:Q9BXJ1-2	intact:EBI-2989|uniprotkb:Q6B1B6|uniprotkb:D6VRQ0|ensemblfungi:YDL100C	intact:EBI-11536642	psi-mi:get3_yeast(display_long)|uniprotkb:YDL100C(locus name)|uniprotkb:GET3(gene name)|psi-mi:GET3(display_short)|uniprotkb:ARR4(gene name synonym)|uniprotkb:D2371(orf name)|uniprotkb:Arsenical pump-driving ATPase(gene name synonym)|uniprotkb:Arsenite-stimulated ATPase(gene name synonym)|uniprotkb:Guided entry of tail-anchored proteins 3(gene name synonym)|uniprotkb:Golgi to ER traffic protein 3(gene name synonym)	psi-mi:q9bxj1-2(display_long)|uniprotkb:CTRP1(gene name synonym)|uniprotkb:G protein-coupled receptor-interacting protein(gene name synonym)|uniprotkb:UNQ310/PRO353(orf name)|uniprotkb:C1QTNF1(gene name)|psi-mi:C1QTNF1(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11547080|imex:IM-24995-2612	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010183.1|sgd:S000002258|dip:DIP-3908N|mint:Q12154|ensemblfungi:YDL100C(gene)|ensemblfungi:YDL100C_mRNA(transcript)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0009408"(response to heat)|go:"GO:0010038"(response to metal ion)|go:"GO:0016787"(hydrolase activity)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043529"(GET complex)|go:"GO:0045048"(protein insertion into ER membrane)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0046872"(metal ion binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:1990507"(obsolete ATP-independent chaperone mediated protein folding)|interpro:IPR016300(Arsenite-transporting ATPase)|interpro:IPR025723|interpro:IPR027417|interpro:IPR027542|rcsb pdb:2WOJ|rcsb pdb:3A36|rcsb pdb:3A37|rcsb pdb:3B2E|rcsb pdb:3H84|rcsb pdb:3IDQ|rcsb pdb:3SJA|rcsb pdb:3SJB|rcsb pdb:3SJC|rcsb pdb:3SJD|rcsb pdb:3VLC|rcsb pdb:3ZS8|rcsb pdb:3ZS9|rcsb pdb:4PWX|rcsb pdb:4XTR|rcsb pdb:4XVU|rcsb pdb:4XWO|rcsb pdb:5BW8|rcsb pdb:5BWK|sgd:YDL100C(identity)	intact:EBI-750200(isoform-parent)|uniprotkb:Q9BXJ1-2(isoform-parent)|entrezgene/locuslink:114897(identity)	-	crc64:F795C359B5A4A461	isoform-comment:No experimental confirmation available.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Y+PTDg+beVeCH5mn4BvWi5wBP4A559292	rogid:zxCXWIEWsl8hYnOP6DlBiu0oiNw9606	intact-crc:9CA2B707E649F7DB|rigid:eVXYasvZvmyJ90iVGaxTTZv/h60	false	-	sufficient binding region:11-291	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O95994	uniprotkb:Q12154	intact:EBI-712648|ensembl:ENSP00000391490	intact:EBI-2989|uniprotkb:Q6B1B6|uniprotkb:D6VRQ0|ensemblfungi:YDL100C	psi-mi:agr2_human(display_long)|uniprotkb:Secreted cement gland protein XAG-2 homolog(gene name synonym)|uniprotkb:HPC8(gene name synonym)|uniprotkb:AG2(gene name synonym)|uniprotkb:UNQ515/PRO1030(orf name)|uniprotkb:AGR2(gene name)|psi-mi:AGR2(display_short)	psi-mi:get3_yeast(display_long)|uniprotkb:YDL100C(locus name)|uniprotkb:GET3(gene name)|psi-mi:GET3(display_short)|uniprotkb:ARR4(gene name synonym)|uniprotkb:D2371(orf name)|uniprotkb:Arsenical pump-driving ATPase(gene name synonym)|uniprotkb:Arsenite-stimulated ATPase(gene name synonym)|uniprotkb:Guided entry of tail-anchored proteins 3(gene name synonym)|uniprotkb:Golgi to ER traffic protein 3(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11547071|imex:IM-24995-2611	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005615"(extracellular space)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0042802"(identical protein binding)|go:"GO:0045742"(positive regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0048546"(digestive tract morphogenesis)|go:"GO:0048639"(positive regulation of developmental growth)|go:"GO:0060480"(lung goblet cell differentiation)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070254"(mucus secretion)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:1903896"(positive regulation of IRE1-mediated unfolded protein response)|go:"GO:1903899"(positive regulation of PERK-mediated unfolded protein response)|interpro:IPR036249|rcsb pdb:2LNS|rcsb pdb:2LNT|ensembl:ENSG00000106541(gene)|ensembl:ENST00000419304(transcript)|go:"GO:0002162"(dystroglycan binding)|go:"GO:0005154"(epidermal growth factor receptor binding)|refseq:NP_006399.1|refseq:XP_005249638.1|dip:DIP-48825N|entrezgene/locuslink:10551(identity)	refseq:NP_010183.1|sgd:S000002258|dip:DIP-3908N|mint:Q12154|ensemblfungi:YDL100C(gene)|ensemblfungi:YDL100C_mRNA(transcript)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0009408"(response to heat)|go:"GO:0010038"(response to metal ion)|go:"GO:0016787"(hydrolase activity)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043529"(GET complex)|go:"GO:0045048"(protein insertion into ER membrane)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0046872"(metal ion binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:1990507"(obsolete ATP-independent chaperone mediated protein folding)|interpro:IPR016300(Arsenite-transporting ATPase)|interpro:IPR025723|interpro:IPR027417|interpro:IPR027542|rcsb pdb:2WOJ|rcsb pdb:3A36|rcsb pdb:3A37|rcsb pdb:3B2E|rcsb pdb:3H84|rcsb pdb:3IDQ|rcsb pdb:3SJA|rcsb pdb:3SJB|rcsb pdb:3SJC|rcsb pdb:3SJD|rcsb pdb:3VLC|rcsb pdb:3ZS8|rcsb pdb:3ZS9|rcsb pdb:4PWX|rcsb pdb:4XTR|rcsb pdb:4XVU|rcsb pdb:4XWO|rcsb pdb:5BW8|rcsb pdb:5BWK|sgd:YDL100C(identity)	-	-	crc64:F795C359B5A4A461	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:E824a1MDXuGzk23ohjS7HAeEx5U9606	rogid:Y+PTDg+beVeCH5mn4BvWi5wBP4A559292	intact-crc:F1D4C49F0FEAD0E3|rigid:hXSL9mu7GabI1rRK2Hhhykh85Mw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12154	uniprotkb:O95967	intact:EBI-2989|uniprotkb:Q6B1B6|uniprotkb:D6VRQ0|ensemblfungi:YDL100C	intact:EBI-743414|uniprotkb:O75967|uniprotkb:A8K7R4|uniprotkb:B3KM31|uniprotkb:B3KQT1|ensembl:ENSP00000309953|ensembl:ENSP00000435295	psi-mi:get3_yeast(display_long)|uniprotkb:YDL100C(locus name)|uniprotkb:GET3(gene name)|psi-mi:GET3(display_short)|uniprotkb:ARR4(gene name synonym)|uniprotkb:D2371(orf name)|uniprotkb:Arsenical pump-driving ATPase(gene name synonym)|uniprotkb:Arsenite-stimulated ATPase(gene name synonym)|uniprotkb:Guided entry of tail-anchored proteins 3(gene name synonym)|uniprotkb:Golgi to ER traffic protein 3(gene name synonym)	psi-mi:fbln4_human(display_long)|uniprotkb:Fibulin-4(gene name synonym)|uniprotkb:Protein UPH1(gene name synonym)|uniprotkb:EFEMP2(gene name)|psi-mi:EFEMP2(display_short)|uniprotkb:FBLN4(gene name synonym)|uniprotkb:UNQ200/PRO226(orf name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11547062|imex:IM-24995-2610	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010183.1|sgd:S000002258|dip:DIP-3908N|mint:Q12154|ensemblfungi:YDL100C(gene)|ensemblfungi:YDL100C_mRNA(transcript)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0009408"(response to heat)|go:"GO:0010038"(response to metal ion)|go:"GO:0016787"(hydrolase activity)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043529"(GET complex)|go:"GO:0045048"(protein insertion into ER membrane)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0046872"(metal ion binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:1990507"(obsolete ATP-independent chaperone mediated protein folding)|interpro:IPR016300(Arsenite-transporting ATPase)|interpro:IPR025723|interpro:IPR027417|interpro:IPR027542|rcsb pdb:2WOJ|rcsb pdb:3A36|rcsb pdb:3A37|rcsb pdb:3B2E|rcsb pdb:3H84|rcsb pdb:3IDQ|rcsb pdb:3SJA|rcsb pdb:3SJB|rcsb pdb:3SJC|rcsb pdb:3SJD|rcsb pdb:3VLC|rcsb pdb:3ZS8|rcsb pdb:3ZS9|rcsb pdb:4PWX|rcsb pdb:4XTR|rcsb pdb:4XVU|rcsb pdb:4XWO|rcsb pdb:5BW8|rcsb pdb:5BWK|sgd:YDL100C(identity)	refseq:NP_058634.4|ensembl:ENSG00000172638(gene)|ensembl:ENST00000307998(transcript)|ensembl:ENST00000531972(transcript)|go:"GO:0001527"(microfibril)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0008201"(heparin binding)|go:"GO:0031012"(extracellular matrix)|go:"GO:0035904"(aorta development)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0048251"(elastic fiber assembly)|go:"GO:0060414"(aorta smooth muscle tissue morphogenesis)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071953"(elastic fiber)|go:"GO:0097084"(vascular associated smooth muscle cell development)|go:"GO:1903561"(extracellular vesicle)|go:"GO:1904026"(regulation of collagen fibril organization)|go:"GO:1904028"(positive regulation of collagen fibril organization)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1904831"(positive regulation of aortic smooth muscle cell differentiation)|go:"GO:1905609"(positive regulation of smooth muscle cell-matrix adhesion)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR018097|interpro:IPR026823|interpro:IPR026824|mint:O95967|rcsb pdb:2KL7|reactome:R-HSA-2129379|dip:DIP-34518N|entrezgene/locuslink:30008(identity)	-	crc64:F795C359B5A4A461	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Y+PTDg+beVeCH5mn4BvWi5wBP4A559292	rogid:L8jMp8rFYb6DRRusfWgyd9zN2KI9606	intact-crc:373E454B1B9C67CE|rigid:/akFsFjlNJyDpjpxsyG/tWm3cig	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8WTR7	uniprotkb:Q12161	intact:EBI-751409|uniprotkb:Q9ULS9|uniprotkb:Q9Y4Q7|uniprotkb:A8K8T7|intact:EBI-28978826|ensembl:ENSP00000270617|ensembl:ENSP00000375697|ensembl:ENSP00000472808	intact:EBI-34372|uniprotkb:D6W213|ensemblfungi:YOL054W	psi-mi:zn473_human(display_long)|uniprotkb:Zinc finger protein 100 homolog(gene name synonym)|uniprotkb:ZNF473(gene name)|psi-mi:ZNF473(display_short)|uniprotkb:KIAA1141(gene name synonym)|uniprotkb:ZFP100(gene name synonym)	psi-mi:psh1_yeast(display_long)|uniprotkb:PSH1(gene name)|psi-mi:PSH1(display_short)|uniprotkb:POB3/SPT16 histone-associated protein 1(gene name synonym)|uniprotkb:O1263(orf name)|uniprotkb:YOL054W(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11547182|imex:IM-24995-2622	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001006657.1|refseq:NP_056243.1|ensembl:ENSP00000270617|ensembl:ENSP00000375697|ensembl:ENSP00000472808|refseq:NP_001295353.1|ensembl:ENSG00000142528(gene)|ensembl:ENST00000270617(transcript)|ensembl:ENST00000391821(transcript)|ensembl:ENST00000595661(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006398"(mRNA 3'-end processing by stem-loop binding and cleavage)|go:"GO:0015030"(Cajal body)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|rcsb pdb:2EMB|rcsb pdb:2EMC|rcsb pdb:2EME|rcsb pdb:2EOU|rcsb pdb:2EOX|rcsb pdb:2EOY|rcsb pdb:2EOZ|rcsb pdb:2YRH|rcsb pdb:2YRJ|rcsb pdb:2YSV|rcsb pdb:2YTD|rcsb pdb:2YTE|rcsb pdb:2YTT|rcsb pdb:2YU5|reactome:R-HSA-111367|reactome:R-HSA-212436|reactome:R-HSA-73856|reactome:R-HSA-77588|entrezgene/locuslink:25888(identity)	refseq:NP_014587.1|sgd:S000005415|mint:Q12161|dip:DIP-6481N|ensemblfungi:YOL054W(gene)|ensemblfungi:YOL054W_mRNA(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|sgd:YOL054W(identity)	-	-	crc64:CE0ECBCB6D465554	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Tm+mqhJ8JVqLYFprsek+VYhcnOI9606	rogid:AvPMRd/GjfaTyQjEfMPhBVcvOs4559292	intact-crc:01F6C2B20F32AC30|rigid:9TdmBK0UL0UE5I8qwhuByTvAazU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12161	uniprotkb:Q8N7W2-2	intact:EBI-34372|uniprotkb:D6W213|ensemblfungi:YOL054W	intact:EBI-10181188|ensembl:ENSP00000367868	psi-mi:psh1_yeast(display_long)|uniprotkb:PSH1(gene name)|psi-mi:PSH1(display_short)|uniprotkb:POB3/SPT16 histone-associated protein 1(gene name synonym)|uniprotkb:O1263(orf name)|uniprotkb:YOL054W(locus name)	psi-mi:q8n7w2-2(display_long)|uniprotkb:C10orf30(gene name synonym)|uniprotkb:BEND7(gene name)|psi-mi:BEND7(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11547171|imex:IM-24995-2621	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014587.1|sgd:S000005415|mint:Q12161|dip:DIP-6481N|ensemblfungi:YOL054W(gene)|ensemblfungi:YOL054W_mRNA(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|sgd:YOL054W(identity)	ensembl:ENSG00000165626(gene)|ensembl:ENST00000378605(transcript)|intact:EBI-743382(isoform-parent)|uniprotkb:Q8N7W2-2(isoform-parent)|entrezgene/locuslink:222389(identity)	-	crc64:CE0ECBCB6D465554	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:AvPMRd/GjfaTyQjEfMPhBVcvOs4559292	rogid:p6qrTn80hLyVU0W2Tvwn50Q4m5I9606	intact-crc:56AF24ECD5296527|rigid:KM2IIjxphzbMyRqwAMNC5CTyd7g	false	-	sufficient binding region:10-374	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12161	uniprotkb:Q7L190	intact:EBI-34372|uniprotkb:D6W213|ensemblfungi:YOL054W	intact:EBI-710457|intact:EBI-28975079|ensembl:ENSP00000335306|uniprotkb:Q9H9N5|uniprotkb:Q9NVI6|uniprotkb:A8K4M7	psi-mi:psh1_yeast(display_long)|uniprotkb:PSH1(gene name)|psi-mi:PSH1(display_short)|uniprotkb:POB3/SPT16 histone-associated protein 1(gene name synonym)|uniprotkb:O1263(orf name)|uniprotkb:YOL054W(locus name)	psi-mi:dppa4_human(display_long)|uniprotkb:DPPA4(gene name)|psi-mi:DPPA4(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11547160|imex:IM-24995-2620	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014587.1|sgd:S000005415|mint:Q12161|dip:DIP-6481N|ensemblfungi:YOL054W(gene)|ensemblfungi:YOL054W_mRNA(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|sgd:YOL054W(identity)	refseq:NP_060659.3|mint:Q7L190|reactome:R-HSA-2892247|ensembl:ENSG00000121570(gene)|ensembl:ENST00000335658(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0048731"(system development)|go:"GO:0060484"(lung-associated mesenchyme development)|interpro:IPR025891|interpro:IPR025892|interpro:IPR039590|interpro:IPR039836|ensembl:ENSP00000335306|entrezgene/locuslink:55211(identity)	-	crc64:CE0ECBCB6D465554	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:AvPMRd/GjfaTyQjEfMPhBVcvOs4559292	rogid:WKqQ0ipAAfKsDRuXJhtTWJcROdc9606	intact-crc:2E4510E6F9F4A98F|rigid:ntfXmWM1RHuN/MhAxByifxCsJw4	false	-	sufficient binding region:11-304	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q5VSY0	uniprotkb:Q12161	intact:EBI-743722|uniprotkb:Q9BYI2|uniprotkb:Q96LI0|uniprotkb:Q9BYI1|uniprotkb:Q9H225|ensembl:ENSP00000365550	intact:EBI-34372|uniprotkb:D6W213|ensemblfungi:YOL054W	psi-mi:gkap1_human(display_long)|uniprotkb:GKAP42(gene name synonym)|uniprotkb:cGMP-dependent protein kinase-anchoring protein of 42 kDa(gene name synonym)|uniprotkb:FKSG21(orf name)|uniprotkb:GKAP1(gene name)|psi-mi:GKAP1(display_short)	psi-mi:psh1_yeast(display_long)|uniprotkb:PSH1(gene name)|psi-mi:PSH1(display_short)|uniprotkb:POB3/SPT16 histone-associated protein 1(gene name synonym)|uniprotkb:O1263(orf name)|uniprotkb:YOL054W(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11547151|imex:IM-24995-2619	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000165113(gene)|refseq:NP_001129425.1|refseq:NP_079487.2|refseq:XP_011517360.1|refseq:XP_005252298.1|ensembl:ENST00000376371(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0007165"(signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|interpro:IPR026109|dip:DIP-47324N|entrezgene/locuslink:80318(identity)	refseq:NP_014587.1|sgd:S000005415|mint:Q12161|dip:DIP-6481N|ensemblfungi:YOL054W(gene)|ensemblfungi:YOL054W_mRNA(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|sgd:YOL054W(identity)	-	-	crc64:CE0ECBCB6D465554	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:WPAqDDTftv300tbwXkusTo6tmUo9606	rogid:AvPMRd/GjfaTyQjEfMPhBVcvOs4559292	intact-crc:0AC0036C2EBA7220|rigid:zR49SS5SPC1KEyxWuv82qic6mjc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38432	uniprotkb:Q12161	intact:EBI-945751|uniprotkb:B2R931|ensembl:ENSP00000240316	intact:EBI-34372|uniprotkb:D6W213|ensemblfungi:YOL054W	psi-mi:coil_human(display_long)|uniprotkb:COIL(gene name)|psi-mi:COIL(display_short)|uniprotkb:CLN80(gene name synonym)|uniprotkb:p80-coilin(gene name synonym)	psi-mi:psh1_yeast(display_long)|uniprotkb:PSH1(gene name)|psi-mi:PSH1(display_short)|uniprotkb:POB3/SPT16 histone-associated protein 1(gene name synonym)|uniprotkb:O1263(orf name)|uniprotkb:YOL054W(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11547142|imex:IM-24995-2618	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004636.1|dip:DIP-38503N|ensembl:ENSG00000121058(gene)|ensembl:ENST00000240316(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0015030"(Cajal body)|go:"GO:0016020"(membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0030619"(U1 snRNA binding)|go:"GO:0030620"(U2 snRNA binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR024822|interpro:IPR031722|mint:P38432|entrezgene/locuslink:8161(identity)	refseq:NP_014587.1|sgd:S000005415|mint:Q12161|dip:DIP-6481N|ensemblfungi:YOL054W(gene)|ensemblfungi:YOL054W_mRNA(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|sgd:YOL054W(identity)	-	-	crc64:CE0ECBCB6D465554	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:hd5p6AbyA/GYNEeca99Mdb41qM09606	rogid:AvPMRd/GjfaTyQjEfMPhBVcvOs4559292	intact-crc:3745925524C63AF7|rigid:i3wOX+p5AKSKep1XoOjc9ScJKf8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P23511-2	uniprotkb:Q12161	intact:EBI-11061759|ensembl:ENSP00000229418	intact:EBI-34372|uniprotkb:D6W213|ensemblfungi:YOL054W	psi-mi:p23511-2(display_long)|uniprotkb:NFYA(gene name)|psi-mi:NFYA(display_short)|uniprotkb:CAAT box DNA-binding protein subunit A(gene name synonym)|uniprotkb:Nuclear transcription factor Y subunit A(gene name synonym)	psi-mi:psh1_yeast(display_long)|uniprotkb:PSH1(gene name)|psi-mi:PSH1(display_short)|uniprotkb:POB3/SPT16 histone-associated protein 1(gene name synonym)|uniprotkb:O1263(orf name)|uniprotkb:YOL054W(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11547133|imex:IM-24995-2617	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-389739(isoform-parent)|ensembl:ENSG00000001167(gene)|ensembl:ENST00000353205(transcript)|uniprotkb:P23511-2(isoform-parent)|entrezgene/locuslink:4800(identity)	refseq:NP_014587.1|sgd:S000005415|mint:Q12161|dip:DIP-6481N|ensemblfungi:YOL054W(gene)|ensemblfungi:YOL054W_mRNA(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|sgd:YOL054W(identity)	-	-	crc64:CE0ECBCB6D465554	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:9IOUoaGszX6kd9hzrCj6BBkgJ+09606	rogid:AvPMRd/GjfaTyQjEfMPhBVcvOs4559292	intact-crc:D69FE4791F936E2B|rigid:DUrLoLDtg9vUEdl/j7cl4a61p34	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12161	uniprotkb:P15622-3	intact:EBI-34372|uniprotkb:D6W213|ensemblfungi:YOL054W	intact:EBI-10177272|ensembl:ENSP00000393442	psi-mi:psh1_yeast(display_long)|uniprotkb:PSH1(gene name)|psi-mi:PSH1(display_short)|uniprotkb:POB3/SPT16 histone-associated protein 1(gene name synonym)|uniprotkb:O1263(orf name)|uniprotkb:YOL054W(locus name)	psi-mi:p15622-3(display_long)|uniprotkb:ZNF647(gene name synonym)|uniprotkb:Zinc finger protein 647(gene name synonym)|uniprotkb:ZNF250(gene name)|psi-mi:ZNF250(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11547122|imex:IM-24995-2616	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014587.1|sgd:S000005415|mint:Q12161|dip:DIP-6481N|ensemblfungi:YOL054W(gene)|ensemblfungi:YOL054W_mRNA(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|sgd:YOL054W(identity)	ensembl:ENSG00000196150(gene)|ensembl:ENST00000417550(transcript)|intact:EBI-739678(isoform-parent)|uniprotkb:P15622-3(isoform-parent)|entrezgene/locuslink:58500(identity)	-	crc64:CE0ECBCB6D465554	isoform-comment:No experimental confirmation available.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:AvPMRd/GjfaTyQjEfMPhBVcvOs4559292	rogid:4AVjeOREEATULMJWtdeZt7rhi889606	intact-crc:2A5311F6B8D4686F|rigid:yRJou5+PcnSKbx49lLrit7cH2y0	false	-	sufficient binding region:46-555	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9NTW7	uniprotkb:Q12161	intact:EBI-711679|uniprotkb:Q9NTS7|uniprotkb:Q9NVH4|ensembl:ENSP00000355179|intact:EBI-10965088|intact:EBI-8637652|intact:MINT-8162399|intact:EBI-745730|uniprotkb:A2A2N4|uniprotkb:Q53H69|uniprotkb:Q53XQ1|uniprotkb:Q5JWM0|uniprotkb:Q5JWM1|uniprotkb:Q8WU98|uniprotkb:Q9H9P1|uniprotkb:Q9NPA5	intact:EBI-34372|uniprotkb:D6W213|ensemblfungi:YOL054W	psi-mi:zf64b_human(display_long)|uniprotkb:Zinc finger protein 338(gene name synonym)|uniprotkb:ZFP64(gene name)|psi-mi:ZFP64(display_short)|uniprotkb:ZNF338(gene name synonym)	psi-mi:psh1_yeast(display_long)|uniprotkb:PSH1(gene name)|psi-mi:PSH1(display_short)|uniprotkb:POB3/SPT16 histone-associated protein 1(gene name synonym)|uniprotkb:O1263(orf name)|uniprotkb:YOL054W(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11547245|imex:IM-24995-2629	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_955459.2|ensembl:ENSG00000020256(gene)|ensembl:ENST00000361387(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|rcsb pdb:1X5W|rcsb pdb:2DMD|interpro:IPR036236|refseq:NP_001306075.1|refseq:NP_060667.2|refseq:NP_071371.3|refseq:NP_955458.1|entrezgene/locuslink:55734(identity)	refseq:NP_014587.1|sgd:S000005415|mint:Q12161|dip:DIP-6481N|ensemblfungi:YOL054W(gene)|ensemblfungi:YOL054W_mRNA(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|sgd:YOL054W(identity)	-	-	crc64:CE0ECBCB6D465554	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2019/04/15	rogid:aTPOj1Ms8ghVMxTJUwnDUyonUQU9606	rogid:AvPMRd/GjfaTyQjEfMPhBVcvOs4559292	intact-crc:B20046EC7213CB5D|rigid:H1grh63KX7jGkuDU2e4yb81EM2Q	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9NTW7	uniprotkb:Q12161	intact:EBI-711679|uniprotkb:Q9NTS7|uniprotkb:Q9NVH4|ensembl:ENSP00000355179|intact:EBI-10965088|intact:EBI-8637652|intact:MINT-8162399|intact:EBI-745730|uniprotkb:A2A2N4|uniprotkb:Q53H69|uniprotkb:Q53XQ1|uniprotkb:Q5JWM0|uniprotkb:Q5JWM1|uniprotkb:Q8WU98|uniprotkb:Q9H9P1|uniprotkb:Q9NPA5	intact:EBI-34372|uniprotkb:D6W213|ensemblfungi:YOL054W	psi-mi:zf64b_human(display_long)|uniprotkb:Zinc finger protein 338(gene name synonym)|uniprotkb:ZFP64(gene name)|psi-mi:ZFP64(display_short)|uniprotkb:ZNF338(gene name synonym)	psi-mi:psh1_yeast(display_long)|uniprotkb:PSH1(gene name)|psi-mi:PSH1(display_short)|uniprotkb:POB3/SPT16 histone-associated protein 1(gene name synonym)|uniprotkb:O1263(orf name)|uniprotkb:YOL054W(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11547236|imex:IM-24995-2628	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_955459.2|ensembl:ENSG00000020256(gene)|ensembl:ENST00000361387(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|rcsb pdb:1X5W|rcsb pdb:2DMD|interpro:IPR036236|refseq:NP_001306075.1|refseq:NP_060667.2|refseq:NP_071371.3|refseq:NP_955458.1|entrezgene/locuslink:55734(identity)	refseq:NP_014587.1|sgd:S000005415|mint:Q12161|dip:DIP-6481N|ensemblfungi:YOL054W(gene)|ensemblfungi:YOL054W_mRNA(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|sgd:YOL054W(identity)	-	-	crc64:CE0ECBCB6D465554	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2019/04/15	rogid:aTPOj1Ms8ghVMxTJUwnDUyonUQU9606	rogid:AvPMRd/GjfaTyQjEfMPhBVcvOs4559292	intact-crc:64B09F2FA3F80EB0|rigid:H1grh63KX7jGkuDU2e4yb81EM2Q	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9HCK0	uniprotkb:Q12161	intact:EBI-3918996|ensembl:ENSP00000362758|ensembl:ENSP00000362760|uniprotkb:B3KQ53|uniprotkb:Q8WTR1	intact:EBI-34372|uniprotkb:D6W213|ensemblfungi:YOL054W	psi-mi:zbt26_human(display_long)|uniprotkb:ZBTB26(gene name)|psi-mi:ZBTB26(display_short)|uniprotkb:KIAA1572(gene name synonym)|uniprotkb:ZNF481(gene name synonym)|uniprotkb:Zinc finger protein 481(gene name synonym)|uniprotkb:Zinc finger protein Bioref(gene name synonym)	psi-mi:psh1_yeast(display_long)|uniprotkb:PSH1(gene name)|psi-mi:PSH1(display_short)|uniprotkb:POB3/SPT16 histone-associated protein 1(gene name synonym)|uniprotkb:O1263(orf name)|uniprotkb:YOL054W(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11547227|imex:IM-24995-2627	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000171448(gene)|ensembl:ENST00000373654(transcript)|ensembl:ENST00000373656(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|refseq:NP_001291292.1|refseq:NP_001291293.1|refseq:NP_065975.1|entrezgene/locuslink:57684(identity)	refseq:NP_014587.1|sgd:S000005415|mint:Q12161|dip:DIP-6481N|ensemblfungi:YOL054W(gene)|ensemblfungi:YOL054W_mRNA(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|sgd:YOL054W(identity)	-	-	crc64:CE0ECBCB6D465554	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:o5XKyl1Z7AtQOJH5HBqkYh5w1n89606	rogid:AvPMRd/GjfaTyQjEfMPhBVcvOs4559292	intact-crc:D27011FA03F55FF7|rigid:jKLBoB6/t8N4vc0+0DqdOEqdbWY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12161	uniprotkb:Q9H9D4	intact:EBI-34372|uniprotkb:D6W213|ensemblfungi:YOL054W	intact:EBI-347633|ensembl:ENSP00000309606	psi-mi:psh1_yeast(display_long)|uniprotkb:PSH1(gene name)|psi-mi:PSH1(display_short)|uniprotkb:POB3/SPT16 histone-associated protein 1(gene name synonym)|uniprotkb:O1263(orf name)|uniprotkb:YOL054W(locus name)	psi-mi:zn408_human(display_long)|uniprotkb:ZNF408(gene name)|psi-mi:ZNF408(display_short)|uniprotkb:PFM14(gene name synonym)|uniprotkb:PRDM17(gene name synonym)|uniprotkb:PR domain zinc finger protein 17(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11547218|imex:IM-24995-2626	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014587.1|sgd:S000005415|mint:Q12161|dip:DIP-6481N|ensemblfungi:YOL054W(gene)|ensemblfungi:YOL054W_mRNA(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|sgd:YOL054W(identity)	refseq:NP_001171680.1|refseq:NP_079017.1|ensembl:ENSG00000175213(gene)|ensembl:ENST00000311764(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR044412|entrezgene/locuslink:79797(identity)	-	crc64:CE0ECBCB6D465554	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:AvPMRd/GjfaTyQjEfMPhBVcvOs4559292	rogid:VYheZbRzNxXoFvtRSwYv//yTtOU9606	intact-crc:176BCA974C82E183|rigid:TLsLvV1Wg8fZQazeThoTw+yKyxE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12161	uniprotkb:Q9BWC9	intact:EBI-34372|uniprotkb:D6W213|ensemblfungi:YOL054W	intact:EBI-711501|ensembl:ENSP00000309681|ensembl:ENSP00000465757|uniprotkb:Q99786|ensembl:ENSP00000466870|ensembl:ENSP00000468539|uniprotkb:B3KUF9|uniprotkb:D3K183	psi-mi:psh1_yeast(display_long)|uniprotkb:PSH1(gene name)|psi-mi:PSH1(display_short)|uniprotkb:POB3/SPT16 histone-associated protein 1(gene name synonym)|uniprotkb:O1263(orf name)|uniprotkb:YOL054W(locus name)	psi-mi:cc106_human(display_long)|uniprotkb:CCDC106(gene name)|psi-mi:CCDC106(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11547209|imex:IM-24995-2625	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014587.1|sgd:S000005415|mint:Q12161|dip:DIP-6481N|ensemblfungi:YOL054W(gene)|ensemblfungi:YOL054W_mRNA(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|sgd:YOL054W(identity)	ensembl:ENSG00000173581(gene)|ensembl:ENST00000308964(transcript)|ensembl:ENST00000586790(transcript)|ensembl:ENST00000588740(transcript)|ensembl:ENST00000591578(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR031591|refseq:NP_037433.2|refseq:XP_005258884.1|refseq:XP_005258885.1|entrezgene/locuslink:29903(identity)	-	crc64:CE0ECBCB6D465554	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:AvPMRd/GjfaTyQjEfMPhBVcvOs4559292	rogid:i15R76tObPsPuullqYoTxebAIC09606	intact-crc:DE863FC5484A3183|rigid:Q6sxByKFDf9HnDLF5/Oba8hmifw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96Q35-2	uniprotkb:Q12161	intact:EBI-11533409|ensembl:ENSP00000376086|ensembl:ENSP00000412073	intact:EBI-34372|uniprotkb:D6W213|ensemblfungi:YOL054W	psi-mi:q96q35-2(display_long)|uniprotkb:FLACC1(gene name)|psi-mi:FLACC1(display_short)|uniprotkb:ALS2CR12(gene name synonym)|uniprotkb:Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 12 protein(gene name synonym)	psi-mi:psh1_yeast(display_long)|uniprotkb:PSH1(gene name)|psi-mi:PSH1(display_short)|uniprotkb:POB3/SPT16 histone-associated protein 1(gene name synonym)|uniprotkb:O1263(orf name)|uniprotkb:YOL054W(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11547200|imex:IM-24995-2624	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-750451(isoform-parent)|uniprotkb:Q96Q35-2(isoform-parent)|ensembl:ENSG00000155749(gene)|ensembl:ENST00000392257(transcript)|ensembl:ENST00000439709(transcript)|entrezgene/locuslink:130540(identity)	refseq:NP_014587.1|sgd:S000005415|mint:Q12161|dip:DIP-6481N|ensemblfungi:YOL054W(gene)|ensemblfungi:YOL054W_mRNA(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|sgd:YOL054W(identity)	-	isoform-comment:No experimental confirmation available.	crc64:CE0ECBCB6D465554	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:bdqsMHSGebh2qVAwEO8DhTbZOHM9606	rogid:AvPMRd/GjfaTyQjEfMPhBVcvOs4559292	intact-crc:3DBBCB1A8E6E66BF|rigid:9Lw5c07SoW0m9ntpxDUfHEqxDkQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q969J2	uniprotkb:Q12161	intact:EBI-2818641|uniprotkb:B2RE32|uniprotkb:Q5U7L4|intact:EBI-28979011|ensembl:ENSP00000366509	intact:EBI-34372|uniprotkb:D6W213|ensemblfungi:YOL054W	psi-mi:zksc4_human(display_long)|uniprotkb:ZKSCAN4(gene name)|psi-mi:ZKSCAN4(display_short)|uniprotkb:ZNF307(gene name synonym)|uniprotkb:ZNF427(gene name synonym)|uniprotkb:P373c6.1(gene name synonym)|uniprotkb:Zinc finger protein 307(gene name synonym)|uniprotkb:Zinc finger protein 427(gene name synonym)	psi-mi:psh1_yeast(display_long)|uniprotkb:PSH1(gene name)|psi-mi:PSH1(display_short)|uniprotkb:POB3/SPT16 histone-associated protein 1(gene name synonym)|uniprotkb:O1263(orf name)|uniprotkb:YOL054W(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11547191|imex:IM-24995-2623	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_061983.2|ensembl:ENSP00000366509|ensembl:ENSG00000187626(gene)|ensembl:ENST00000377294(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|interpro:IPR038269|mint:Q969J2|reactome:R-HSA-212436|refseq:XP_005249152.1|entrezgene/locuslink:387032(identity)	refseq:NP_014587.1|sgd:S000005415|mint:Q12161|dip:DIP-6481N|ensemblfungi:YOL054W(gene)|ensemblfungi:YOL054W_mRNA(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|sgd:YOL054W(identity)	-	-	crc64:CE0ECBCB6D465554	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:5TWhAtzfmCXHkOSbjKwjgLIsCcs9606	rogid:AvPMRd/GjfaTyQjEfMPhBVcvOs4559292	intact-crc:BAAD0D51591C42D4|rigid:WiqvZDzvfklS89IxQr5U6KY8I3U	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12208	uniprotkb:Q9P1Z2	intact:EBI-31589|uniprotkb:D6VYC7|ensemblfungi:YLR132C	intact:EBI-749920|uniprotkb:B3KVA8|uniprotkb:Q6FI59|uniprotkb:Q71RC3|uniprotkb:Q86WF8|uniprotkb:Q96JU3|uniprotkb:Q9H090|intact:EBI-2558801|ensembl:ENSP00000449960	psi-mi:usb1_yeast(display_long)|uniprotkb:USB1(gene name)|psi-mi:USB1(display_short)|uniprotkb:U six biogenesis protein 1(gene name synonym)|uniprotkb:L3127(orf name)|uniprotkb:YLR132C(locus name)	psi-mi:caco1_human(display_long)|uniprotkb:CALCOCO1(gene name)|psi-mi:CALCOCO1(display_short)|uniprotkb:KIAA1536(gene name synonym)|uniprotkb:Calphoglin(gene name synonym)|uniprotkb:Sarcoma antigen NY-SAR-3(gene name synonym)|uniprotkb:Coiled-coil coactivator protein(gene name synonym)|uniprotkb:PP13275(orf name)|uniprotkb:UNQ2436/PRO4996(orf name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11547326|imex:IM-24995-2638	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013233.1|sgd:S000004122|dip:DIP-2147N|mint:Q12208|ensemblfungi:YLR132C(gene)|ensemblfungi:YLR132C_mRNA(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0008663"(2',3'-cyclic-nucleotide 2'-phosphodiesterase activity)|go:"GO:0034477"(U6 snRNA 3'-end processing)|go:"GO:1990838"("poly(U)-specific exoribonuclease activity, producing 3' uridine cyclic phosphate ends")|interpro:IPR027521|rcsb pdb:5UQJ|sgd:YLR132C(identity)	refseq:NP_001137154.1|refseq:NP_065949.1|refseq:XP_016875196.1|dip:DIP-47322N|ensembl:ENSG00000012822(gene)|ensembl:ENST00000550804(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0007165"(signal transduction)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0070016"(armadillo repeat domain binding)|interpro:IPR012852(Coiled-coil transcriptional coactivator-like)|interpro:IPR041611|interpro:IPR041641|mint:Q9P1Z2|entrezgene/locuslink:57658(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:vJ6GZFlbc3RC9UKZdc4+yyCFQfs559292	rogid:4M9Qyq+7GZ1w2UAN6k0ntGQNTvw9606	intact-crc:C99D6383A26B7018|rigid:uDRyJNp12uggzE8+eBl83Rl0XIc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12208	uniprotkb:O95198	intact:EBI-31589|uniprotkb:D6VYC7|ensemblfungi:YLR132C	intact:EBI-746999|uniprotkb:B2RD18|uniprotkb:Q8N484|uniprotkb:Q8TBH5|uniprotkb:A6NCM7|uniprotkb:B4DFH7|uniprotkb:F5H6M3|ensembl:ENSP00000226725	psi-mi:usb1_yeast(display_long)|uniprotkb:USB1(gene name)|psi-mi:USB1(display_short)|uniprotkb:U six biogenesis protein 1(gene name synonym)|uniprotkb:L3127(orf name)|uniprotkb:YLR132C(locus name)	psi-mi:klhl2_human(display_long)|uniprotkb:Actin-binding protein Mayven(gene name synonym)|uniprotkb:KLHL2(gene name)|psi-mi:KLHL2(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11547317|imex:IM-24995-2637	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013233.1|sgd:S000004122|dip:DIP-2147N|mint:Q12208|ensemblfungi:YLR132C(gene)|ensemblfungi:YLR132C_mRNA(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0008663"(2',3'-cyclic-nucleotide 2'-phosphodiesterase activity)|go:"GO:0034477"(U6 snRNA 3'-end processing)|go:"GO:1990838"("poly(U)-specific exoribonuclease activity, producing 3' uridine cyclic phosphate ends")|interpro:IPR027521|rcsb pdb:5UQJ|sgd:YLR132C(identity)	refseq:NP_001154993.1|refseq:NP_001154994.1|refseq:NP_009177.3|refseq:NP_001317952.1|refseq:NP_001317953.1|refseq:XP_016863165.1|ensembl:ENSG00000109466(gene)|ensembl:ENST00000226725(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030027"(lamellipodium)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR017096(Kelch-like protein, gigaxonin)|interpro:IPR044072|mint:O95198|rcsb pdb:2XN4|rcsb pdb:4CHB|reactome:R-HSA-8951664|reactome:R-HSA-983168|go:"GO:0042802"(identical protein binding)|entrezgene/locuslink:11275(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:vJ6GZFlbc3RC9UKZdc4+yyCFQfs559292	rogid:tFegR2lJZccRqs4qUjdT3PNjNnk9606	intact-crc:18EB13BB17323A8D|rigid:ts2j2gMDPH3Sq0bObY1YW9/ucnc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96BA8	uniprotkb:Q12207	intact:EBI-6942903|ensembl:ENSP00000481956|intact:MINT-268046|intact:MINT-8162577|uniprotkb:Q8N2D5|uniprotkb:Q96CP0	intact:EBI-11922|ensemblfungi:YPR149W|uniprotkb:D6W4E6	psi-mi:cr3l1_human(display_long)|uniprotkb:CREB3L1(gene name)|psi-mi:CREB3L1(display_short)|uniprotkb:OASIS(gene name synonym)|uniprotkb:PSEC0238(orf name)|uniprotkb:Old astrocyte specifically-induced substance(gene name synonym)	psi-mi:nce2_yeast(display_long)|uniprotkb:NCE102(gene name)|psi-mi:NCE102(display_short)|uniprotkb:NCE2(gene name synonym)|uniprotkb:RTG2S2(gene name synonym)|uniprotkb:YPR149W(locus name)|uniprotkb:P9659.2(orf name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11547308|imex:IM-24995-2636	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157613(gene)|ensembl:ENST00000621158(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0070278"(extracellular matrix constituent secretion)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029805|mint:Q96BA8|reactome:R-HSA-8874211|refseq:NP_443086.1|entrezgene/locuslink:90993(identity)	ensemblfungi:YPR149W(gene)|ensemblfungi:YPR149W_mRNA(transcript)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0009306"(protein secretion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032126"(eisosome)|go:"GO:0033101"(cellular bud membrane)|go:"GO:0060237"(regulation of fungal-type cell wall organization)|go:"GO:0061091"(regulation of phospholipid translocation)|go:"GO:0070941"(eisosome assembly)|go:"GO:0071944"(cell periphery)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR008253(Marvel)|go:"GO:0070250"(mating projection membrane)|refseq:NP_015475.1|sgd:S000006353|dip:DIP-5397N|sgd:YPR149W(identity)	-	comment:mint|function:"Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE"	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:sMWUFmBeBBCO+T0Y2CuB/un1lBg9606	rogid:oSD/cLHQuPxlB/s1v7MZUihJ3XM559292	intact-crc:B006F9BC1E09B0DB|rigid:HJ1uGOLC78ud7cdARENohYzFxfM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12206	uniprotkb:P63279	intact:EBI-20571|uniprotkb:D6W2T3|ensemblfungi:YOR229W	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	psi-mi:wtm2_yeast(display_long)|uniprotkb:WTM2(gene name)|psi-mi:WTM2(display_short)|uniprotkb:YOR50-19(orf name)|uniprotkb:YOR229W(locus name)	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11547299|imex:IM-24995-2635	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014872.1|sgd:S000005755|ensemblfungi:YOR229W(gene)|ensemblfungi:YOR229W_mRNA(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010674"(negative regulation of transcription from RNA polymerase II promoter involved in meiotic cell cycle)|go:"GO:0031939"(obsolete negative regulation of chromatin silencing at telomere)|go:"GO:0034629"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061186"(negative regulation of silent mating-type cassette heterochromatin assembly)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|reactome:R-SCE-3214815|reactome:R-SCE-3214847|reactome:R-SCE-3214858|dip:DIP-1534N|mint:Q12206|sgd:YOR229W(identity)	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N|entrezgene/locuslink:7329(identity)	-	crc64:4A8F5F879B88AA94	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:DCudPHib/PxB5+S+RRONJQyC+QI559292	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	intact-crc:184F1FF561F85E03|rigid:H3X0HgaZER9jaXMMANTE6+zp2Xg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12196	uniprotkb:Q9H190	intact:EBI-15224|uniprotkb:Q00602|uniprotkb:D6W2H8|ensemblfungi:YOR119C	intact:EBI-742426|ensembl:ENSP00000371233|uniprotkb:O95892|uniprotkb:Q5W0X1|uniprotkb:Q9BZ42|uniprotkb:Q9H567|uniprotkb:Q9NRY8|intact:EBI-28983470|ensembl:ENSP00000342935|ensembl:ENSP00000354013	psi-mi:rio1_yeast(display_long)|uniprotkb:RIO1(gene name)|psi-mi:RIO1(display_short)|uniprotkb:RRP10(gene name synonym)|uniprotkb:O3266(orf name)|uniprotkb:YOR3266C(orf name)|uniprotkb:YOR119C(locus name)|uniprotkb:Ribosomal RNA-processing protein 10(gene name synonym)	psi-mi:sdcb2_human(display_long)|uniprotkb:Similar to TACIP18(gene name synonym)|uniprotkb:SDCBP2(gene name)|psi-mi:SDCBP2(display_short)|uniprotkb:SITAC18(gene name synonym)|uniprotkb:Syndecan-binding protein 2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11547290|imex:IM-24995-2634	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005645|reactome:R-SCE-6791226|refseq:NP_014762.3|ensemblfungi:YOR119C(gene)|ensemblfungi:YOR119C_mRNA(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0016479"(negative regulation of transcription by RNA polymerase I)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0030874"(nucleolar chromatin)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000234"(positive regulation of rRNA processing)|interpro:IPR000687(RIO kinase)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017407(Serine/threonine-protein kinase Rio1)|interpro:IPR018935|go:"GO:0030490"(maturation of SSU-rRNA)|dip:DIP-4146N|sgd:YOR119C(identity)	refseq:NP_001186713.1|refseq:NP_056500.2|refseq:NP_536737.3|ensembl:ENSP00000342935|ensembl:ENSP00000354013|ensembl:ENST00000381808|ensembl:ENSP00000371229|ensembl:ENSP00000371233|ensembl:ENSG00000125775(gene)|ensembl:ENST00000360779(transcript)|ensembl:ENST00000381812(transcript)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007399"(nervous system development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016607"(nuclear speck)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046907"(intracellular transport)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036034|interpro:IPR041489|ensembl:ENST00000339987(transcript)|entrezgene/locuslink:27111(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:wLf+Zbnca7AHLdHkLrakVxXltKw559292	rogid:vlEtVZkwLTte5PJ4i8ce+SwE/4Y9606	intact-crc:B40B1703DFC78F5F|rigid:BbGHj1eDv/Y2183yBJaJc8WoQFY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48775	uniprotkb:Q12181	intact:EBI-743494|ensembl:ENSP00000444788|ensembl:ENSP00000460086|uniprotkb:A8K053	intact:EBI-37624|uniprotkb:D6W456|ensemblfungi:YPR048W	psi-mi:t23o_human(display_long)|uniprotkb:Tryptophan pyrrolase(gene name synonym)|uniprotkb:Tryptophan oxygenase(gene name synonym)|uniprotkb:Tryptamin 2,3-dioxygenase(gene name synonym)|uniprotkb:TDO2(gene name)|psi-mi:TDO2(display_short)|uniprotkb:TDO(gene name synonym)|uniprotkb:Tryptophanase(gene name synonym)	psi-mi:ndor1_yeast(display_long)|uniprotkb:TAH18(gene name)|psi-mi:TAH18(display_short)|uniprotkb:NADPH-dependent FMN and FAD-containing oxidoreductase(gene name synonym)|uniprotkb:YP9499.06(orf name)|uniprotkb:YPR048W(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11547281|imex:IM-24995-2633	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000151790(gene)|ensembl:ENSG00000262635(gene)|ensembl:ENST00000536354(transcript)|ensembl:ENST00000573403(transcript)|go:"GO:0004833"(tryptophan 2,3-dioxygenase activity)|go:"GO:0005829"(cytosol)|go:"GO:0016597"(amino acid binding)|go:"GO:0019441"(tryptophan catabolic process to kynurenine)|go:"GO:0019442"(tryptophan catabolic process to acetyl-CoA)|go:"GO:0019825"(oxygen binding)|go:"GO:0020037"(heme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051289"(protein homotetramerization)|go:"GO:1904842"(response to nitroglycerin)|interpro:IPR004981(Tryptophan 2,3-dioxygenase)|interpro:IPR037217|mint:P48775|rcsb pdb:4PW8|rcsb pdb:5TI9|rcsb pdb:5TIA|rcsb pdb:6A4I|rcsb pdb:6PYY|rcsb pdb:6PYZ|rcsb pdb:6UD5|rcsb pdb:6VBN|reactome:R-HSA-71240|refseq:NP_005642.1|entrezgene/locuslink:6999(identity)	refseq:NP_015373.1|sgd:S000006252|dip:DIP-1688N|mint:Q12181|ensemblfungi:YPR048W(gene)|ensemblfungi:YPR048W_mRNA(transcript)|go:"GO:0003958"(NADPH-hemoprotein reductase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006809"(nitric oxide biosynthetic process)|go:"GO:0010181"(FMN binding)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0016651"("oxidoreductase activity, acting on NAD(P)H")|go:"GO:0016709"("oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen")|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0050660"(flavin adenine dinucleotide binding)|go:"GO:0050661"(NADP binding)|go:"GO:1901300"(positive regulation of hydrogen peroxide-mediated programmed cell death)|interpro:IPR001094(Flavodoxin-like)|interpro:IPR001433("Oxidoreductase FAD/NAD(P)-binding")|interpro:IPR001709(Flavoprotein pyridine nucleotide cytochrome reductase)|interpro:IPR003097(FAD-binding, type 1)|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|interpro:IPR017927|interpro:IPR017938|interpro:IPR023173|interpro:IPR028879|interpro:IPR029039|interpro:IPR039261|sgd:YPR048W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:S+cyc710I52nIFQWgKhXFul9QZw9606	rogid:rMyciB2K1QEFDXSgbMznNQ811ko559292	intact-crc:BBFD249FEEB7E758|rigid:1u/mvEqDXQHhIKCOK6b8SxQgzxs	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12181	uniprotkb:O14641	intact:EBI-37624|uniprotkb:D6W456|ensemblfungi:YPR048W	intact:EBI-740850|ensembl:ENSP00000005340|uniprotkb:Q53XM0|uniprotkb:D3DTN3	psi-mi:ndor1_yeast(display_long)|uniprotkb:TAH18(gene name)|psi-mi:TAH18(display_short)|uniprotkb:NADPH-dependent FMN and FAD-containing oxidoreductase(gene name synonym)|uniprotkb:YP9499.06(orf name)|uniprotkb:YPR048W(locus name)	psi-mi:dvl2_human(display_long)|uniprotkb:DSH homolog 2(gene name synonym)|uniprotkb:DVL2(gene name)|psi-mi:DVL2(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11547272|imex:IM-24995-2632	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015373.1|sgd:S000006252|dip:DIP-1688N|mint:Q12181|ensemblfungi:YPR048W(gene)|ensemblfungi:YPR048W_mRNA(transcript)|go:"GO:0003958"(NADPH-hemoprotein reductase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006809"(nitric oxide biosynthetic process)|go:"GO:0010181"(FMN binding)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0016651"("oxidoreductase activity, acting on NAD(P)H")|go:"GO:0016709"("oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen")|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0050660"(flavin adenine dinucleotide binding)|go:"GO:0050661"(NADP binding)|go:"GO:1901300"(positive regulation of hydrogen peroxide-mediated programmed cell death)|interpro:IPR001094(Flavodoxin-like)|interpro:IPR001433("Oxidoreductase FAD/NAD(P)-binding")|interpro:IPR001709(Flavoprotein pyridine nucleotide cytochrome reductase)|interpro:IPR003097(FAD-binding, type 1)|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|interpro:IPR017927|interpro:IPR017938|interpro:IPR023173|interpro:IPR028879|interpro:IPR029039|interpro:IPR039261|sgd:YPR048W(identity)	refseq:NP_004413.1|ensembl:ENSG00000004975(gene)|ensembl:ENST00000005340(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005109"(frizzled binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0007507"(heart development)|go:"GO:0016235"(aggresome)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044340"(canonical Wnt signaling pathway involved in regulation of cell proliferation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0150012"(positive regulation of neuron projection arborization)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008341(Dishevelled-2 region)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:O14641|rcsb pdb:2REY|rcsb pdb:3CBX|rcsb pdb:3CBY|rcsb pdb:3CBZ|rcsb pdb:3CC0|rcsb pdb:4WIP|rcsb pdb:5LNP|rcsb pdb:5SUY|rcsb pdb:5SUZ|rcsb pdb:6IW3|rcsb pdb:6JCK|reactome:R-HSA-201681|reactome:R-HSA-201688|reactome:R-HSA-2028269|reactome:R-HSA-4086400|reactome:R-HSA-4608870|reactome:R-HSA-4641258|reactome:R-HSA-4641262|reactome:R-HSA-5099900|reactome:R-HSA-5368598|reactome:R-HSA-5663220|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9673324|ensembl:ENSP00000005340|dip:DIP-34433N|entrezgene/locuslink:1856(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:rMyciB2K1QEFDXSgbMznNQ811ko559292	rogid:2Vdc8oRnT4Mz/j+EXQXrL3AszOc9606	intact-crc:B879C4D6E3145D30|rigid:iqBO894eW/Epd9Iqd6bwnrTVipU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12161	uniprotkb:Q9Y294	intact:EBI-34372|uniprotkb:D6W213|ensemblfungi:YOL054W	intact:EBI-749553|uniprotkb:Q6IA08|uniprotkb:Q9P014|ensembl:ENSP00000229595	psi-mi:psh1_yeast(display_long)|uniprotkb:PSH1(gene name)|psi-mi:PSH1(display_short)|uniprotkb:POB3/SPT16 histone-associated protein 1(gene name synonym)|uniprotkb:O1263(orf name)|uniprotkb:YOL054W(locus name)	psi-mi:asf1a_human(display_long)|uniprotkb:Anti-silencing function protein 1 homolog A(gene name synonym)|uniprotkb:CCG1-interacting factor A(gene name synonym)|uniprotkb:ASF1A(gene name)|psi-mi:ASF1A(display_short)|uniprotkb:CGI-98(orf name)|uniprotkb:HSPC146(orf name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11547263|imex:IM-24995-2631	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014587.1|sgd:S000005415|mint:Q12161|dip:DIP-6481N|ensemblfungi:YOL054W(gene)|ensemblfungi:YOL054W_mRNA(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|sgd:YOL054W(identity)	refseq:NP_054753.1|dip:DIP-29241N|ensembl:ENSG00000111875(gene)|ensembl:ENST00000229595(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0042692"(muscle cell differentiation)|interpro:IPR006818(Anti-silencing protein, ASF1-like)|interpro:IPR036747|mint:Q9Y294|rcsb pdb:1TEY|rcsb pdb:2I32|rcsb pdb:2IIJ|rcsb pdb:2IO5|rcsb pdb:3AAD|rcsb pdb:5C3I|rcsb pdb:6F0G|rcsb pdb:6F0H|rcsb pdb:6ZUF|reactome:R-HSA-2559584|rcsb pdb:6F0F|entrezgene/locuslink:25842(identity)	-	crc64:CE0ECBCB6D465554	caution:This sequence has been withdrawn from Uniprot.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:AvPMRd/GjfaTyQjEfMPhBVcvOs4559292	rogid:rIMptRSOYD+wfp0dMEHjhNNsHXQ9606	intact-crc:BFDB2B0A732E400D|rigid:yPa4Yh8Wg9LcdUz1Ez3K/7ckA9M	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9NVV9	uniprotkb:Q12161	intact:EBI-741515|uniprotkb:Q53FQ1|uniprotkb:Q6IA99|ensembl:ENSP00000254250|uniprotkb:A6NCB6|uniprotkb:D3DSY5|uniprotkb:H9KV49	intact:EBI-34372|uniprotkb:D6W213|ensemblfungi:YOL054W	psi-mi:thap1_human(display_long)|uniprotkb:THAP1(gene name)|psi-mi:THAP1(display_short)	psi-mi:psh1_yeast(display_long)|uniprotkb:PSH1(gene name)|psi-mi:PSH1(display_short)|uniprotkb:POB3/SPT16 histone-associated protein 1(gene name synonym)|uniprotkb:O1263(orf name)|uniprotkb:YOL054W(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11547254|imex:IM-24995-2630	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060575.1|ensembl:ENSG00000131931(gene)|ensembl:ENST00000254250(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001650"(fibrillar center)|go:"GO:0001935"(endothelial cell proliferation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007049"(cell cycle)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016605"(PML body)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR006612(Zinc finger, C2CH-type)|interpro:IPR026516|interpro:IPR038441|mint:Q9NVV9|rcsb pdb:2JTG|rcsb pdb:2KO0|rcsb pdb:2L1G|refseq:NP_945354.1|entrezgene/locuslink:55145(identity)	refseq:NP_014587.1|sgd:S000005415|mint:Q12161|dip:DIP-6481N|ensemblfungi:YOL054W(gene)|ensemblfungi:YOL054W_mRNA(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|sgd:YOL054W(identity)	-	-	crc64:CE0ECBCB6D465554	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:/KO90pu5tBnIVq9SMx1JYPXFCEQ9606	rogid:AvPMRd/GjfaTyQjEfMPhBVcvOs4559292	intact-crc:CE42CCDB4B6500FD|rigid:cAs9Rb52eg8KN0sVdXYKvRhbD7E	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O76083-2	uniprotkb:Q12259	intact:EBI-11524542|ensembl:ENSP00000335242	intact:EBI-30776|uniprotkb:D6VYA8|ensemblfungi:YLR108C	psi-mi:o76083-2(display_long)|uniprotkb:PDE9A(gene name)|psi-mi:PDE9A(display_short)	psi-mi:yl108_yeast(display_long)|uniprotkb:L2913(orf name)|uniprotkb:YLR108C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11547389|imex:IM-24995-2645	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-742764(isoform-parent)|ensembl:ENSG00000160191(gene)|ensembl:ENST00000335512(transcript)|uniprotkb:O76083-2(isoform-parent)|entrezgene/locuslink:5152(identity)	refseq:NP_013209.1|sgd:S000004098|dip:DIP-4075N|ensemblfungi:YLR108C(gene)|ensemblfungi:YLR108C_mRNA(transcript)|go:"GO:0005634"(nucleus)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|sgd:YLR108C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:nTzgeYGOwTM/7VJUgxSnlnDiCFo9606	rogid:CzknxXhhvgMp3J0/oi197EgZ05U559292	intact-crc:A8180F78183D4581|rigid:fim0piZtR6WM9l8dZTek4YNZ1UE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O60684	uniprotkb:Q12259	intact:EBI-359923|uniprotkb:Q5VVU3|uniprotkb:B2RDC7|ensembl:ENSP00000362728|uniprotkb:D3DPP5	intact:EBI-30776|uniprotkb:D6VYA8|ensemblfungi:YLR108C	psi-mi:ima7_human(display_long)|uniprotkb:KPNA6(gene name)|psi-mi:KPNA6(display_short)|uniprotkb:IPOA7(gene name synonym)|uniprotkb:Karyopherin subunit alpha-6(gene name synonym)	psi-mi:yl108_yeast(display_long)|uniprotkb:L2913(orf name)|uniprotkb:YLR108C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11547380|imex:IM-24995-2644	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_036448.1|ensembl:ENSG00000025800(gene)|ensembl:ENST00000373625(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0016020"(membrane)|go:"GO:0019079"(viral genome replication)|go:"GO:0030682"(mitigation of host defenses by symbiont)|go:"GO:0043657"(host cell)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060135"(maternal process involved in female pregnancy)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0075506"(entry of viral genome into host nucleus through nuclear pore complex via importin)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:1903902"(positive regulation of viral life cycle)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|mint:O60684|rcsb pdb:4UAD|dip:DIP-27609N|entrezgene/locuslink:23633(identity)	refseq:NP_013209.1|sgd:S000004098|dip:DIP-4075N|ensemblfungi:YLR108C(gene)|ensemblfungi:YLR108C_mRNA(transcript)|go:"GO:0005634"(nucleus)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|sgd:YLR108C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:3NsSIcE6BHIqYlvfGRolUKD/5uc9606	rogid:CzknxXhhvgMp3J0/oi197EgZ05U559292	intact-crc:158576C13A96246D|rigid:j/EP5iQ6fQ+ovJ/LwhRXlkbPquY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12259	uniprotkb:O43597	intact:EBI-30776|uniprotkb:D6VYA8|ensemblfungi:YLR108C	intact:EBI-742487|uniprotkb:Q5T6Z7|ensembl:ENSP00000366306|ensembl:ENSP00000366308|uniprotkb:B2R9J9	psi-mi:yl108_yeast(display_long)|uniprotkb:L2913(orf name)|uniprotkb:YLR108C(locus name)	psi-mi:spy2_human(display_long)|uniprotkb:SPRY2(gene name)|psi-mi:SPRY2(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11547371|imex:IM-24995-2643	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013209.1|sgd:S000004098|dip:DIP-4075N|ensemblfungi:YLR108C(gene)|ensemblfungi:YLR108C_mRNA(transcript)|go:"GO:0005634"(nucleus)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|sgd:YLR108C(identity)	refseq:NP_005833.1|rcsb pdb:5HL0|reactome:R-HSA-1295596|reactome:R-HSA-182971|rcsb pdb:5HKZ|ensembl:ENST00000377102(transcript)|ensembl:ENST00000377104(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|ensembl:ENSG00000136158(gene)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030291"(protein serine/threonine kinase inhibitor activity)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031345"(negative regulation of cell projection organization)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0032587"(ruffle membrane)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0045165"(cell fate commitment)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048513"(animal organ development)|go:"GO:0051387"(negative regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060437"(lung growth)|go:"GO:0060449"(bud elongation involved in lung branching)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:1900747"(negative regulation of vascular endothelial growth factor signaling pathway)|go:"GO:1902747"(negative regulation of lens fiber cell differentiation)|go:"GO:1990752"(microtubule end)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR007875(Sprouty)|interpro:IPR030780|mint:O43597|rcsb pdb:3BUM|rcsb pdb:3OB1|rcsb pdb:5HKY|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|refseq:NP_001305465.1|refseq:NP_001305466.1|refseq:NP_001305467.1|entrezgene/locuslink:10253(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:CzknxXhhvgMp3J0/oi197EgZ05U559292	rogid:u1omauzisc6MdZlogMotUmtauSI9606	intact-crc:851ECF5CBFA5DA70|rigid:XtjQAWbzgnuhpfG/brce/m9nrpo	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O00629	uniprotkb:Q12259	intact:EBI-396343|uniprotkb:O00190|intact:EBI-28976443|ensembl:ENSP00000334373|uniprotkb:A8K4S6|uniprotkb:D3DNM2	intact:EBI-30776|uniprotkb:D6VYA8|ensemblfungi:YLR108C	psi-mi:ima3_human(display_long)|uniprotkb:KPNA4(gene name)|psi-mi:KPNA4(display_short)|uniprotkb:QIP1(gene name synonym)|uniprotkb:Karyopherin subunit alpha-4(gene name synonym)|uniprotkb:Importin alpha Q1(gene name synonym)	psi-mi:yl108_yeast(display_long)|uniprotkb:L2913(orf name)|uniprotkb:YLR108C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11547362|imex:IM-24995-2642	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002259.1|ensembl:ENSG00000186432(gene)|ensembl:ENST00000334256(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0061608"(nuclear import signal receptor activity)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|mint:O00629|rcsb pdb:4UAE|rcsb pdb:5TBK|rcsb pdb:5XZX|rcsb pdb:6BVV|rcsb pdb:6BVZ|rcsb pdb:6BW9|rcsb pdb:6BWA|rcsb pdb:6BWB|rcsb pdb:6WX8|rcsb pdb:7JJL|reactome:R-HSA-1169408|reactome:R-HSA-168276|ensembl:ENSP00000334373|dip:DIP-32982N|entrezgene/locuslink:3840(identity)	refseq:NP_013209.1|sgd:S000004098|dip:DIP-4075N|ensemblfungi:YLR108C(gene)|ensemblfungi:YLR108C_mRNA(transcript)|go:"GO:0005634"(nucleus)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|sgd:YLR108C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:/cng/xZ42E2juzHNOpuQTP+amx89606	rogid:CzknxXhhvgMp3J0/oi197EgZ05U559292	intact-crc:F98370E84F1F1177|rigid:fHEBdR7ZCTLMeY5BYZl1AgEg6R8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12259	uniprotkb:O00505	intact:EBI-30776|uniprotkb:D6VYA8|ensemblfungi:YLR108C	intact:EBI-358297|intact:EBI-28976892|ensembl:ENSP00000261667|uniprotkb:O00191|uniprotkb:O43195|uniprotkb:Q96AA7|uniprotkb:Q5JVM9|intact:EBI-742146|uniprotkb:Q8IYQ9	psi-mi:yl108_yeast(display_long)|uniprotkb:L2913(orf name)|uniprotkb:YLR108C(locus name)	psi-mi:ima4_human(display_long)|uniprotkb:KPNA3(gene name)|psi-mi:KPNA3(display_short)|uniprotkb:QIP2(gene name synonym)|uniprotkb:Karyopherin subunit alpha-3(gene name synonym)|uniprotkb:SRP1-gamma(gene name synonym)|uniprotkb:Importin alpha Q2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11547353|imex:IM-24995-2641	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013209.1|sgd:S000004098|dip:DIP-4075N|ensemblfungi:YLR108C(gene)|ensemblfungi:YLR108C_mRNA(transcript)|go:"GO:0005634"(nucleus)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|sgd:YLR108C(identity)	ensembl:ENSG00000102753(gene)|ensembl:ENST00000261667(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0043657"(host cell)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0075732"(viral penetration into host nucleus)|interpro:IPR000225(Armadillo)|refseq:NP_002258.2|ensembl:ENSP00000261667|dip:DIP-27586N|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|mint:O00505|reactome:R-HSA-1169408|reactome:R-HSA-168276|entrezgene/locuslink:3839(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:CzknxXhhvgMp3J0/oi197EgZ05U559292	rogid:kx/oTYWMYG7dhwJHvr1POLD6FTU9606	intact-crc:23EA592C5D7034D5|rigid:oP3wJrtr1SKXCew1E2EWVOCtGX4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12245	uniprotkb:Q8TAP6	intact:EBI-2343020|uniprotkb:D6W3M5|uniprotkb:Q6Q5F7|ensemblfungi:YPL144W	intact:EBI-742887|ensembl:ENSP00000262127|uniprotkb:Q658N5|uniprotkb:Q9H9U7|uniprotkb:B0YJB2|uniprotkb:B4DXG5|uniprotkb:B4DZW1	psi-mi:poc4_yeast(display_long)|uniprotkb:POC4(gene name)|psi-mi:POC4(display_short)|uniprotkb:YPL144W(locus name)|uniprotkb:DMP1(gene name synonym)	psi-mi:cep76_human(display_long)|uniprotkb:CEP76(gene name)|psi-mi:CEP76(display_short)|uniprotkb:C18orf9(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11547344|imex:IM-24995-2640	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015181.1|sgd:S000006065|dip:DIP-8930N|mint:Q12245|ensemblfungi:YPL144W(gene)|ensemblfungi:YPL144W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043248"(proteasome assembly)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|interpro:IPR018854|rcsb pdb:2Z5B|rcsb pdb:2Z5C|sgd:YPL144W(identity)	refseq:NP_079175.2|ensembl:ENSG00000101624(gene)|ensembl:ENST00000262127(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0046599"(regulation of centriole replication)|interpro:IPR028926|interpro:IPR038765|mint:Q8TAP6|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_001258918.1|entrezgene/locuslink:79959(identity)	-	crc64:1CC7C6074CF4AC08	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:IT8/s4OOCv/pZK9VkZJ5J8ye438559292	rogid:fWzb8oIU35oVWomyDrf8u5sbxUk9606	intact-crc:1CD56476229C1E77|rigid:a56IIFxvfAseknEUcfwhRs6fS6c	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12211	uniprotkb:P35606	intact:EBI-14272|uniprotkb:D6W3F8|ensemblfungi:YPL212C	intact:EBI-1056534|uniprotkb:B4DZI8|intact:EBI-11019844|ensembl:ENSP00000329419	psi-mi:pus1_yeast(display_long)|uniprotkb:YPL212C(locus name)|uniprotkb:tRNA-uridine isomerase 1(gene name synonym)|uniprotkb:PUS1(gene name)|psi-mi:PUS1(display_short)|uniprotkb:tRNA pseudouridylate synthase 1(gene name synonym)	psi-mi:copb2_human(display_long)|uniprotkb:COPB2(gene name)|psi-mi:COPB2(display_short)|uniprotkb:Beta'-coat protein(gene name synonym)|uniprotkb:p102(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11547335|imex:IM-24995-2639	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015112.1|sgd:S000006133|ensemblfungi:YPL212C(gene)|ensemblfungi:YPL212C_mRNA(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006400"(tRNA modification)|go:"GO:0009982"(pseudouridine synthase activity)|go:"GO:0031120"(snRNA pseudouridine synthesis)|go:"GO:1990481"(mRNA pseudouridine synthesis)|interpro:IPR001406(tRNA pseudouridine synthase)|interpro:IPR020094|go:"GO:0031119"(tRNA pseudouridine synthesis)|interpro:IPR020097|interpro:IPR020103|interpro:IPR041708|mint:Q12211|dip:DIP-5344N|sgd:YPL212C(identity)	refseq:NP_004757.1|ensembl:ENSG00000184432(gene)|ensembl:ENST00000333188(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0030133"(transport vesicle)|go:"GO:1901998"(toxin transport)|interpro:IPR001680(WD40 repeat)|interpro:IPR006692(Coatomer, WD associated region)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016453(Coatomer, beta' subunit)|interpro:IPR020472|interpro:IPR036322|mint:P35606|reactome:R-HSA-6807878|reactome:R-HSA-6811434|refseq:XP_016863001.1|dip:DIP-27603N|entrezgene/locuslink:9276(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:u8LVhy6qxRakYcjrKYN0QGn34iM559292	rogid:zkd7lOeV+OvHglnAJg6cXoMhgbg9606	intact-crc:9B0E50DB72296AB9|rigid:h57e73cZRMo6xEO7IjDBkBDTFCc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12259	uniprotkb:Q8WV44	intact:EBI-30776|uniprotkb:D6VYA8|ensemblfungi:YLR108C	intact:EBI-725997|uniprotkb:Q5BKT0|uniprotkb:Q7L484|uniprotkb:Q96Q10|intact:EBI-1551110|uniprotkb:Q9BSL8|uniprotkb:B3KNJ6|uniprotkb:D3DWR9|ensembl:ENSP00000320869	psi-mi:yl108_yeast(display_long)|uniprotkb:L2913(orf name)|uniprotkb:YLR108C(locus name)	psi-mi:tri41_human(display_long)|uniprotkb:TRIM41(gene name)|psi-mi:TRIM41(display_short)|uniprotkb:RINCK(gene name synonym)|uniprotkb:Tripartite motif-containing protein 41(gene name synonym)|uniprotkb:RING finger-interacting protein with C kinase(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM41(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11547456|imex:IM-24995-2652	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013209.1|sgd:S000004098|dip:DIP-4075N|ensemblfungi:YLR108C(gene)|ensemblfungi:YLR108C_mRNA(transcript)|go:"GO:0005634"(nucleus)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|sgd:YLR108C(identity)	refseq:NP_291027.3|refseq:NP_963921.1|ensembl:ENSG00000146063(gene)|ensembl:ENST00000315073(transcript)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0042802"(identical protein binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071225"(cellular response to muramyl dipeptide)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR042828|interpro:IPR043136|mint:Q8WV44|rcsb pdb:2EGM|reactome:R-HSA-983168|entrezgene/locuslink:90933(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:CzknxXhhvgMp3J0/oi197EgZ05U559292	rogid:BVqf0OHXPGsYe8F66mHzvD4XQ549606	intact-crc:0F490F24B0AAE48F|rigid:/RwvnIwtpDT3qyFJmHFHGzE5acQ	false	-	sufficient binding region:86-630	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12259	uniprotkb:Q8N6L0	intact:EBI-30776|uniprotkb:D6VYA8|ensemblfungi:YLR108C	intact:EBI-749265|uniprotkb:Q96MC3|ensembl:ENSP00000404220	psi-mi:yl108_yeast(display_long)|uniprotkb:L2913(orf name)|uniprotkb:YLR108C(locus name)	psi-mi:kash5_human(display_long)|uniprotkb:KASH5(gene name)|psi-mi:KASH5(display_short)|uniprotkb:CCDC155(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 155(gene name synonym)|uniprotkb:KASH domain-containing protein 5(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11547447|imex:IM-24995-2651	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013209.1|sgd:S000004098|dip:DIP-4075N|ensemblfungi:YLR108C(gene)|ensemblfungi:YLR108C_mRNA(transcript)|go:"GO:0005634"(nucleus)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|sgd:YLR108C(identity)	refseq:NP_653289.3|ensembl:ENSG00000161609(gene)|ensembl:ENST00000447857(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034397"(telomere localization)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051225"(spindle assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0090172"(microtubule cytoskeleton organization involved in homologous chromosome segregation)|go:"GO:0090220"(chromosome localization to nuclear envelope involved in homologous chromosome segregation)|go:"GO:0090619"(meiotic spindle pole)|interpro:IPR011992(EF-Hand type)|interpro:IPR028168|interpro:IPR028170|interpro:IPR039508|mint:Q8N6L0|rcsb pdb:6R2I|rcsb pdb:6WMF|entrezgene/locuslink:147872(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:CzknxXhhvgMp3J0/oi197EgZ05U559292	rogid:Wl9L7AcvDHCZuKjYLn8QgGIbZTc9606	intact-crc:D0BC6B9924E445BE|rigid:CL3/fEzVgFnXthyaCwbA3LhmLeI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8IYA8	uniprotkb:Q12259	intact:EBI-8638439|intact:EBI-28969497|ensembl:ENSP00000296449|ensembl:ENSP00000391788|ensembl:ENSP00000407837|uniprotkb:C9JJL0|uniprotkb:Q96LP7|intact:MINT-8162095|uniprotkb:Q05DG9	intact:EBI-30776|uniprotkb:D6VYA8|ensemblfungi:YLR108C	psi-mi:iho1_human(display_long)|uniprotkb:IHO1(gene name)|psi-mi:IHO1(display_short)|uniprotkb:CCDC36(gene name synonym)|uniprotkb:Cancer/testis antigen 74(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 36(gene name synonym)	psi-mi:yl108_yeast(display_long)|uniprotkb:L2913(orf name)|uniprotkb:YLR108C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11547436|imex:IM-24995-2650	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000296449|ensembl:ENST00000366429|ensembl:ENSP00000403700|ensembl:ENSP00000391788|ensembl:ENSP00000407837|ensembl:ENSG00000173421(gene)|ensembl:ENST00000296449(transcript)|ensembl:ENST00000438782(transcript)|ensembl:ENST00000452691(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0006310"(DNA recombination)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0042138"(meiotic DNA double-strand break formation)|go:"GO:0048477"(oogenesis)|go:"GO:0060629"(regulation of homologous chromosome segregation)|interpro:IPR031529|mint:Q8IYA8|refseq:XP_011531974.1|refseq:XP_011531975.1|refseq:NP_001128669.1|refseq:NP_835467.2|refseq:XP_006713187.1|entrezgene/locuslink:339834(identity)	refseq:NP_013209.1|sgd:S000004098|dip:DIP-4075N|ensemblfungi:YLR108C(gene)|ensemblfungi:YLR108C_mRNA(transcript)|go:"GO:0005634"(nucleus)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|sgd:YLR108C(identity)	-	comment:mint	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:+TNQLExkhmC1NWqsE240Cx7zFVU9606	rogid:CzknxXhhvgMp3J0/oi197EgZ05U559292	intact-crc:1AB6F2B59FFCB209|rigid:cm1ZX5U6As/tFOEf2aR5MhHMFu0	false	sufficient binding region:11-594	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q6RW13-2	uniprotkb:Q12259	intact:EBI-11522760|ensembl:ENSP00000365816	intact:EBI-30776|uniprotkb:D6VYA8|ensemblfungi:YLR108C	psi-mi:q6rw13-2(display_long)|uniprotkb:AGTRAP(gene name)|psi-mi:AGTRAP(display_short)|uniprotkb:AT1 receptor-associated protein(gene name synonym)|uniprotkb:ATRAP(gene name synonym)	psi-mi:yl108_yeast(display_long)|uniprotkb:L2913(orf name)|uniprotkb:YLR108C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11547427|imex:IM-24995-2649	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000177674(gene)|ensembl:ENST00000376629(transcript)|intact:EBI-741181(isoform-parent)|uniprotkb:Q6RW13-2(isoform-parent)|entrezgene/locuslink:57085(identity)	refseq:NP_013209.1|sgd:S000004098|dip:DIP-4075N|ensemblfungi:YLR108C(gene)|ensemblfungi:YLR108C_mRNA(transcript)|go:"GO:0005634"(nucleus)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|sgd:YLR108C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:PNzVis/8puQZBJ562gCqZKc078s9606	rogid:CzknxXhhvgMp3J0/oi197EgZ05U559292	intact-crc:710C77EEBA84F367|rigid:Y/xDLctUWzrTeJsAQfmQs5tk0h8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q15041	uniprotkb:Q12259	intact:EBI-714543|ensembl:ENSP00000306788|uniprotkb:B7Z6S5|uniprotkb:B7Z791|uniprotkb:F5GXP4	intact:EBI-30776|uniprotkb:D6VYA8|ensemblfungi:YLR108C	psi-mi:ar6p1_human(display_long)|uniprotkb:ARL6IP(gene name synonym)|uniprotkb:ARL6IP1(gene name)|psi-mi:ARL6IP1(display_short)|uniprotkb:KIAA0069(gene name synonym)|uniprotkb:ARMER(gene name synonym)|uniprotkb:Apoptotic regulator in the membrane of the endoplasmic reticulum(gene name synonym)	psi-mi:yl108_yeast(display_long)|uniprotkb:L2913(orf name)|uniprotkb:YLR108C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11547418|imex:IM-24995-2648	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055976.1|ensembl:ENSG00000170540(gene)|ensembl:ENST00000304414(transcript)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006613"(cotranslational protein targeting to membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0071787"(endoplasmic reticulum tubular network formation)|go:"GO:1903371"(regulation of endoplasmic reticulum tubular network organization)|go:"GO:1990809"(endoplasmic reticulum tubular network membrane organization)|interpro:IPR033301|mint:Q15041|go:"GO:0002038"(positive regulation of L-glutamate import across plasma membrane)|refseq:NP_001300787.1|entrezgene/locuslink:23204(identity)	refseq:NP_013209.1|sgd:S000004098|dip:DIP-4075N|ensemblfungi:YLR108C(gene)|ensemblfungi:YLR108C_mRNA(transcript)|go:"GO:0005634"(nucleus)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|sgd:YLR108C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:3fjkoyvUx25po7xsPcXgpjEeLJg9606	rogid:CzknxXhhvgMp3J0/oi197EgZ05U559292	intact-crc:F981EC57715AEB6A|rigid:z/je0n1TVgGyjkTlmk7fJJZoF6Q	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12259	uniprotkb:Q15025	intact:EBI-30776|uniprotkb:D6VYA8|ensemblfungi:YLR108C	intact:EBI-357849|uniprotkb:A4F1W8|uniprotkb:O76008|uniprotkb:Q96EL9|uniprotkb:Q99833|uniprotkb:Q9H1J3|uniprotkb:B7Z699|uniprotkb:Q6N077|ensembl:ENSP00000317891|ensembl:ENSP00000428187|ensembl:ENSP00000430760|uniprotkb:A4F1W9|uniprotkb:A4F1X2|uniprotkb:A4F1X4|uniprotkb:A4F1X5|uniprotkb:A4F1X6|uniprotkb:A4F1X7|uniprotkb:A4F1X9|uniprotkb:E7EPY1|uniprotkb:E7ET96|uniprotkb:Q05KP3|uniprotkb:Q05KP4	psi-mi:yl108_yeast(display_long)|uniprotkb:L2913(orf name)|uniprotkb:YLR108C(locus name)	psi-mi:tnip1_human(display_long)|uniprotkb:TNIP1(gene name)|psi-mi:TNIP1(display_short)|uniprotkb:KIAA0113(gene name synonym)|uniprotkb:NAF1(gene name synonym)|uniprotkb:Nef-associated factor 1(gene name synonym)|uniprotkb:HIV-1 Nef-interacting protein(gene name synonym)|uniprotkb:Virion-associated nuclear shuttling protein(gene name synonym)|uniprotkb:Nip40-1(gene name synonym)|uniprotkb:A20-binding inhibitor of NF-kappa-B activation 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11547408|imex:IM-24995-2647	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013209.1|sgd:S000004098|dip:DIP-4075N|ensemblfungi:YLR108C(gene)|ensemblfungi:YLR108C_mRNA(transcript)|go:"GO:0005634"(nucleus)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|sgd:YLR108C(identity)	refseq:NP_006049.3|refseq:NP_001239319.1|refseq:NP_001239320.1|refseq:NP_001239321.1|refseq:NP_001239322.1|refseq:NP_001245383.1|dip:DIP-27577N|refseq:NP_001239315.1|ensembl:ENSG00000145901(gene)|ensembl:ENST00000315050(transcript)|ensembl:ENST00000521591(transcript)|ensembl:ENST00000522226(transcript)|go:"GO:0002755"(MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0006952"(defense response)|go:"GO:0006954"(inflammatory response)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0009101"(glycoprotein biosynthetic process)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0085032"(modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade)|go:"GO:1903003"(positive regulation of protein deubiquitination)|interpro:IPR033372|mint:Q15025|reactome:R-HSA-5689896|go:"GO:0051019"(mitogen-activated protein kinase binding)|refseq:NP_001239314.1|refseq:NP_001245384.1|refseq:NP_001245385.1|refseq:XP_006714814.1|refseq:XP_006714815.1|entrezgene/locuslink:10318(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:CzknxXhhvgMp3J0/oi197EgZ05U559292	rogid:16Vjb5CuGTAbW2M22qbCxgXtV1o9606	intact-crc:AA059ED4B1B37B89|rigid:cWMyQh0kOz3uytxWbjilqKqnh8o	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12259	uniprotkb:P35520	intact:EBI-30776|uniprotkb:D6VYA8|ensemblfungi:YLR108C	intact:EBI-740135|uniprotkb:Q99425|uniprotkb:Q9BWC5|uniprotkb:B2R993|uniprotkb:D3DSK4|intact:EBI-14245939|ensembl:ENSP00000344460|ensembl:ENSP00000352643|ensembl:ENSP00000381225|ensembl:ENSP00000381231	psi-mi:yl108_yeast(display_long)|uniprotkb:L2913(orf name)|uniprotkb:YLR108C(locus name)	psi-mi:cbs_human(display_long)|uniprotkb:CBS(gene name)|psi-mi:CBS(display_short)|uniprotkb:Serine sulfhydrase(gene name synonym)|uniprotkb:Beta-thionase(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11547398|imex:IM-24995-2646	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013209.1|sgd:S000004098|dip:DIP-4075N|ensemblfungi:YLR108C(gene)|ensemblfungi:YLR108C_mRNA(transcript)|go:"GO:0005634"(nucleus)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|sgd:YLR108C(identity)	refseq:NP_000062.1|refseq:NP_001171479.1|refseq:NP_001171480.1|ensembl:ENSG00000160200(gene)|ensembl:ENST00000352178(transcript)|ensembl:ENST00000359624(transcript)|ensembl:ENST00000398158(transcript)|go:"GO:0004122"(cystathionine beta-synthase activity)|ensembl:ENST00000398165(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006535"(cysteine biosynthetic process from serine)|go:"GO:0006563"(L-serine metabolic process)|go:"GO:0006565"(L-serine catabolic process)|go:"GO:0019343"(cysteine biosynthetic process via cystathionine)|go:"GO:0019344"(cysteine biosynthetic process)|go:"GO:0019346"(transsulfuration)|go:"GO:0019448"(L-cysteine catabolic process)|go:"GO:0019825"(oxygen binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0020037"(heme binding)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042262"(DNA protection)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043418"(homocysteine catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0050421"("nitrite reductase (NO-forming) activity")|go:"GO:0050667"(homocysteine metabolic process)|go:"GO:0070025"(carbon monoxide binding)|go:"GO:0070026"(nitric oxide binding)|go:"GO:0070814"(hydrogen sulfide biosynthetic process)|go:"GO:0072341"(modified amino acid binding)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR001216(Cysteine synthase/cystathionine beta-synthase P-phosphate-binding site)|interpro:IPR001926(Pyridoxal phosphate-dependent enzyme, beta subunit)|interpro:IPR005857(Cystathionine beta-synthase)|interpro:IPR036052|mint:P35520|rcsb pdb:1JBQ|rcsb pdb:1M54|rcsb pdb:4COO|rcsb pdb:4L0D|rcsb pdb:4L27|rcsb pdb:4L28|rcsb pdb:4L3V|rcsb pdb:4PCU|rcsb pdb:4UUU|rcsb pdb:5MMS|reactome:R-HSA-1614603|reactome:R-HSA-2408508|refseq:XP_011528079.1|refseq:XP_011528083.1|refseq:XP_011528084.1|refseq:XP_011544396.1|refseq:XP_011544397.1|refseq:XP_011544399.1|refseq:XP_011544400.1|refseq:XP_011544401.1|refseq:NP_001307227.1|refseq:NP_001308002.1|refseq:XP_016883700.1|refseq:XP_016883701.1|refseq:XP_016883702.1|refseq:XP_016883703.1|refseq:XP_016883704.1|refseq:XP_016883705.1|refseq:XP_016883706.1|refseq:XP_016883707.1|refseq:XP_016883978.1|refseq:XP_016883979.1|refseq:XP_016883980.1|refseq:XP_016883981.1|entrezgene/locuslink:875(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:CzknxXhhvgMp3J0/oi197EgZ05U559292	rogid:f9eo0cPOHppVY7Nqejag3YyK18s9606	intact-crc:6188AA4B383AEEAC|rigid:ewRxuzMo9umkg0gOnUIdBicjMrw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9NWS6	uniprotkb:Q12259	intact:EBI-8638992|uniprotkb:B4DY02|ensembl:ENSP00000216214|ensembl:ENSP00000395892|intact:MINT-8162875|uniprotkb:Q5TII5|uniprotkb:B3KWG4|uniprotkb:Q96CY3	intact:EBI-30776|uniprotkb:D6VYA8|ensemblfungi:YLR108C	psi-mi:f118a_human(display_long)|uniprotkb:FAM118A(gene name)|psi-mi:FAM118A(display_short)|uniprotkb:C22orf8(gene name synonym)	psi-mi:yl108_yeast(display_long)|uniprotkb:L2913(orf name)|uniprotkb:YLR108C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11547530|imex:IM-24995-2660	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000100376(gene)|ensembl:ENST00000216214(transcript)|ensembl:ENST00000441876(transcript)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|interpro:IPR033353|interpro:IPR038916|interpro:IPR039444|refseq:NP_060381.2|refseq:NP_001098065.1|entrezgene/locuslink:55007(identity)	refseq:NP_013209.1|sgd:S000004098|dip:DIP-4075N|ensemblfungi:YLR108C(gene)|ensemblfungi:YLR108C_mRNA(transcript)|go:"GO:0005634"(nucleus)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|sgd:YLR108C(identity)	-	comment:mint	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:zZMOyeZwAeoDNLBQ9EKYRw4+0BM9606	rogid:CzknxXhhvgMp3J0/oi197EgZ05U559292	intact-crc:304C520565508F89|rigid:T1dDPKLlQd2I0aehmcKfvO0ceZU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9NVV9	uniprotkb:Q12259	intact:EBI-741515|uniprotkb:Q53FQ1|uniprotkb:Q6IA99|ensembl:ENSP00000254250|uniprotkb:A6NCB6|uniprotkb:D3DSY5|uniprotkb:H9KV49	intact:EBI-30776|uniprotkb:D6VYA8|ensemblfungi:YLR108C	psi-mi:thap1_human(display_long)|uniprotkb:THAP1(gene name)|psi-mi:THAP1(display_short)	psi-mi:yl108_yeast(display_long)|uniprotkb:L2913(orf name)|uniprotkb:YLR108C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11547521|imex:IM-24995-2659	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060575.1|ensembl:ENSG00000131931(gene)|ensembl:ENST00000254250(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001650"(fibrillar center)|go:"GO:0001935"(endothelial cell proliferation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007049"(cell cycle)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016605"(PML body)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR006612(Zinc finger, C2CH-type)|interpro:IPR026516|interpro:IPR038441|mint:Q9NVV9|rcsb pdb:2JTG|rcsb pdb:2KO0|rcsb pdb:2L1G|refseq:NP_945354.1|entrezgene/locuslink:55145(identity)	refseq:NP_013209.1|sgd:S000004098|dip:DIP-4075N|ensemblfungi:YLR108C(gene)|ensemblfungi:YLR108C_mRNA(transcript)|go:"GO:0005634"(nucleus)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|sgd:YLR108C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:/KO90pu5tBnIVq9SMx1JYPXFCEQ9606	rogid:CzknxXhhvgMp3J0/oi197EgZ05U559292	intact-crc:30FA43B97C5E6965|rigid:HPH0K7k7xwZtExAi0j4OHsry67o	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9HCK0	uniprotkb:Q12259	intact:EBI-3918996|ensembl:ENSP00000362758|ensembl:ENSP00000362760|uniprotkb:B3KQ53|uniprotkb:Q8WTR1	intact:EBI-30776|uniprotkb:D6VYA8|ensemblfungi:YLR108C	psi-mi:zbt26_human(display_long)|uniprotkb:ZBTB26(gene name)|psi-mi:ZBTB26(display_short)|uniprotkb:KIAA1572(gene name synonym)|uniprotkb:ZNF481(gene name synonym)|uniprotkb:Zinc finger protein 481(gene name synonym)|uniprotkb:Zinc finger protein Bioref(gene name synonym)	psi-mi:yl108_yeast(display_long)|uniprotkb:L2913(orf name)|uniprotkb:YLR108C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11547512|imex:IM-24995-2658	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000171448(gene)|ensembl:ENST00000373654(transcript)|ensembl:ENST00000373656(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|refseq:NP_001291292.1|refseq:NP_001291293.1|refseq:NP_065975.1|entrezgene/locuslink:57684(identity)	refseq:NP_013209.1|sgd:S000004098|dip:DIP-4075N|ensemblfungi:YLR108C(gene)|ensemblfungi:YLR108C_mRNA(transcript)|go:"GO:0005634"(nucleus)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|sgd:YLR108C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:o5XKyl1Z7AtQOJH5HBqkYh5w1n89606	rogid:CzknxXhhvgMp3J0/oi197EgZ05U559292	intact-crc:E78D2F076F0CDED7|rigid:5tlb+6Z+vOSQbEKkHD1npNvJT58	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12259	uniprotkb:Q9C0F1	intact:EBI-30776|uniprotkb:D6VYA8|ensemblfungi:YLR108C	intact:EBI-744115|uniprotkb:A8K8W9|uniprotkb:B3KT53|uniprotkb:Q8IXZ4|uniprotkb:A8MW11|uniprotkb:D3DP42|ensembl:ENSP00000296519|ensembl:ENSP00000380009|ensembl:ENSP00000423153	psi-mi:yl108_yeast(display_long)|uniprotkb:L2913(orf name)|uniprotkb:YLR108C(locus name)	psi-mi:cep44_human(display_long)|uniprotkb:HBV PreS1-transactivated protein 3(gene name synonym)|uniprotkb:CEP44(gene name)|psi-mi:CEP44(display_short)|uniprotkb:KIAA1712(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11547503|imex:IM-24995-2657	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013209.1|sgd:S000004098|dip:DIP-4075N|ensemblfungi:YLR108C(gene)|ensemblfungi:YLR108C_mRNA(transcript)|go:"GO:0005634"(nucleus)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|sgd:YLR108C(identity)	refseq:NP_001035247.1|refseq:NP_001138786.1|refseq:XP_011530587.1|refseq:XP_011530588.1|refseq:XP_011530589.1|refseq:XP_016864143.1|refseq:XP_016864144.1|ensembl:ENSG00000164118(gene)|ensembl:ENST00000296519(transcript)|ensembl:ENST00000396791(transcript)|ensembl:ENST00000503780(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007099"(centriole replication)|go:"GO:0008017"(microtubule binding)|go:"GO:0010457"(centriole-centriole cohesion)|go:"GO:0030496"(midbody)|interpro:IPR029157|interpro:IPR033603|mint:Q9C0F1|entrezgene/locuslink:80817(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:CzknxXhhvgMp3J0/oi197EgZ05U559292	rogid:gDTC64oDhudGdsssC7v+suIHZkA9606	intact-crc:255ECBAE5F0B2989|rigid:tQl1GNaqNU+YjUPEuZ8OaQB9VPM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12259	uniprotkb:Q99750	intact:EBI-30776|uniprotkb:D6VYA8|ensemblfungi:YLR108C	intact:EBI-724076|ensembl:ENSP00000230321|ensembl:ENSP00000362142	psi-mi:yl108_yeast(display_long)|uniprotkb:L2913(orf name)|uniprotkb:YLR108C(locus name)	psi-mi:mdfi_human(display_long)|uniprotkb:Myogenic repressor I-mf(gene name synonym)|uniprotkb:MDFI(gene name)|psi-mi:MDFI(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11547494|imex:IM-24995-2656	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013209.1|sgd:S000004098|dip:DIP-4075N|ensemblfungi:YLR108C(gene)|ensemblfungi:YLR108C_mRNA(transcript)|go:"GO:0005634"(nucleus)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|sgd:YLR108C(identity)	refseq:NP_005577.1|ensembl:ENSG00000112559(gene)|ensembl:ENST00000230321(transcript)|ensembl:ENST00000373051(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR026134|mint:Q99750|refseq:NP_001287733.1|refseq:NP_001287734.1|refseq:NP_001287735.1|entrezgene/locuslink:4188(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:CzknxXhhvgMp3J0/oi197EgZ05U559292	rogid:V3vU0fihMOW18DMHAiDbuZ3asNU9606	intact-crc:F5B6421CD9ADB535|rigid:WRPqLXL2xvGWgfOHpP3Zau+273c	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12259	uniprotkb:Q96IK5	intact:EBI-30776|uniprotkb:D6VYA8|ensemblfungi:YLR108C	intact:EBI-2548508|ensembl:ENSP00000282570|uniprotkb:Q9H826|uniprotkb:Q9H8V7|uniprotkb:Q9H927	psi-mi:yl108_yeast(display_long)|uniprotkb:L2913(orf name)|uniprotkb:YLR108C(locus name)	psi-mi:gmcl1_human(display_long)|uniprotkb:GMCL1(gene name)|psi-mi:GMCL1(display_short)|uniprotkb:GCL(gene name synonym)|uniprotkb:BTBD13(gene name synonym)|uniprotkb:SPATA29(gene name synonym)|uniprotkb:Spermatogenesis-associated protein 29(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11547485|imex:IM-24995-2655	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013209.1|sgd:S000004098|dip:DIP-4075N|ensemblfungi:YLR108C(gene)|ensemblfungi:YLR108C_mRNA(transcript)|go:"GO:0005634"(nucleus)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|sgd:YLR108C(identity)	ensembl:ENSG00000087338(gene)|ensembl:ENST00000282570(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0007281"(germ cell development)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016363"(nuclear matrix)|go:"GO:0042802"(identical protein binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR043380|refseq:NP_848526.1|entrezgene/locuslink:64395(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:CzknxXhhvgMp3J0/oi197EgZ05U559292	rogid:ED8yqySVu7BWxpw3DUSNBZSQWrk9606	intact-crc:4BC71A054607197B|rigid:gCLE2yb9pKKf3IwPtUB5pCdLuxk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12259	uniprotkb:Q96BR9	intact:EBI-30776|uniprotkb:D6VYA8|ensemblfungi:YLR108C	intact:EBI-742740|uniprotkb:Q8IUL5|uniprotkb:Q8IWR9|uniprotkb:Q8N2Y5|uniprotkb:Q96BX0|ensembl:ENSP00000362609	psi-mi:yl108_yeast(display_long)|uniprotkb:L2913(orf name)|uniprotkb:YLR108C(locus name)	psi-mi:zbt8a_human(display_long)|uniprotkb:ZBTB8A(gene name)|psi-mi:ZBTB8A(display_short)|uniprotkb:BOZF1(gene name synonym)|uniprotkb:BTB/POZ and zinc-finger domain-containing factor(gene name synonym)|uniprotkb:BTB/POZ and zinc-finger domains factor on chromosome 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11547476|imex:IM-24995-2654	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013209.1|sgd:S000004098|dip:DIP-4075N|ensemblfungi:YLR108C(gene)|ensemblfungi:YLR108C_mRNA(transcript)|go:"GO:0005634"(nucleus)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|sgd:YLR108C(identity)	ensembl:ENSG00000160062(gene)|ensembl:ENST00000373510(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|refseq:NP_001035531.2|refseq:NP_001278425.1|entrezgene/locuslink:653121(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:CzknxXhhvgMp3J0/oi197EgZ05U559292	rogid:tsrPT2tHvuBryODKgRXnceXz9s09606	intact-crc:09AA311C10428D66|rigid:be6cdCb6O91+sI6vlgtKlQHNKKQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q92734	uniprotkb:Q12259	intact:EBI-357061|uniprotkb:Q15656|intact:EBI-357314|uniprotkb:Q969I2|uniprotkb:D3DN49|uniprotkb:K0J5S8|uniprotkb:K0J6K2|intact:EBI-28969365|ensembl:ENSP00000240851|ensembl:ENSP00000419960|ensembl:ENSP00000420797|ensembl:ENSP00000501815|ensembl:ENSP00000502071|ensembl:ENSP00000502450|ensembl:ENSP00000502592|ensembl:ENSP00000502734|uniprotkb:G5E9V1	intact:EBI-30776|uniprotkb:D6VYA8|ensemblfungi:YLR108C	psi-mi:tfg_human(display_long)|uniprotkb:TFG(gene name)|psi-mi:TFG(display_short)|uniprotkb:TRK-fused gene protein(gene name synonym)	psi-mi:yl108_yeast(display_long)|uniprotkb:L2913(orf name)|uniprotkb:YLR108C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11547467|imex:IM-24995-2653	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001007566.1|refseq:NP_001182407.1|refseq:NP_001182408.1|refseq:NP_006061.2|ensembl:ENSP00000240851|ensembl:ENST00000463568|ensembl:ENSP00000419504|ensembl:ENST00000476228|ensembl:ENSP00000417952|ensembl:ENSP00000420797|ensembl:ENSP00000419960|ensembl:ENST00000615993|ensembl:ENSP00000479269|ensembl:ENST00000620299|ensembl:ENSP00000479981|ensembl:ENSP00000502734|ensembl:ENST00000674645|ensembl:ENSP00000501892|ensembl:ENST00000674758|ensembl:ENSP00000502502|ensembl:ENST00000675047|ensembl:ENSP00000502497|ensembl:ENSP00000502592|ensembl:ENST00000675420|ensembl:ENSP00000502516|ensembl:ENSP00000502450|ensembl:ENST00000675543|ensembl:ENSP00000501815|ensembl:ENST00000675586|ensembl:ENSP00000502329|ensembl:ENST00000676111|ensembl:ENSP00000502139|ensembl:ENST00000676308|ensembl:ENSP00000502697|ensembl:ENSP00000502071|ensembl:ENST00000676431|ensembl:ENSP00000502698|ensembl:ENSP00000502229|refseq:XP_006713535.1|refseq:XP_006713536.1|ensembl:ENSG00000114354(gene)|ensembl:ENST00000240851(transcript)|ensembl:ENST00000487505(transcript)|ensembl:ENST00000490574(transcript)|ensembl:ENST00000674615(transcript)|ensembl:ENST00000675243(transcript)|ensembl:ENST00000675499(transcript)|ensembl:ENST00000675553(transcript)|ensembl:ENST00000676395(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048208"(COPII vesicle coating)|go:"GO:0070971"(endoplasmic reticulum exit site)|interpro:IPR000270(Octicosapeptide/Phox/Bem1p)|interpro:IPR033512|interpro:IPR034857|mint:Q92734|reactome:R-HSA-204005|refseq:XP_011510636.1|refseq:XP_005247123.1|refseq:XP_016861016.1|refseq:XP_016861017.1|refseq:XP_016861018.1|refseq:XP_016861019.1|entrezgene/locuslink:10342(identity)	refseq:NP_013209.1|sgd:S000004098|dip:DIP-4075N|ensemblfungi:YLR108C(gene)|ensemblfungi:YLR108C_mRNA(transcript)|go:"GO:0005634"(nucleus)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|sgd:YLR108C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:y7aghh0X3Ewgpzcx5h5nB+X2dII9606	rogid:CzknxXhhvgMp3J0/oi197EgZ05U559292	intact-crc:F50377DC2A07A1D0|rigid:Kmbywoug59wyzgm0IQiNuBFMdqc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P23497-2	uniprotkb:Q12306	intact:EBI-6589365|ensembl:ENSP00000386404	intact:EBI-17490|uniprotkb:D6VTD1|ensemblfungi:YDR510W	psi-mi:p23497-2(display_long)|uniprotkb:SP100(isoform synonym)|uniprotkb:SP100(gene name)|psi-mi:SP100(display_short)|uniprotkb:Nuclear dot-associated Sp100 protein(gene name synonym)|uniprotkb:Speckled 100 kDa(gene name synonym)|uniprotkb:SP100A(isoform synonym)	psi-mi:smt3_yeast(display_long)|uniprotkb:SMT3(gene name)|psi-mi:SMT3(display_short)|uniprotkb:D9719.15(orf name)|uniprotkb:YDR510W(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11547579|imex:IM-24995-2665	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-751145(isoform-parent)|uniprotkb:P23497-2(isoform-parent)|ensembl:ENSG00000067066(gene)|ensembl:ENST00000409341(transcript)|entrezgene/locuslink:6672(identity)	refseq:NP_010798.1|sgd:S000002918|ensemblfungi:YDR510W(gene)|ensemblfungi:YDR510W_mRNA(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005940"(septin ring)|go:"GO:0016925"(protein sumoylation)|go:"GO:0031386"(protein tag)|go:"GO:0042802"(identical protein binding)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR022617|interpro:IPR029071|rcsb pdb:1EUV|rcsb pdb:1L2N|rcsb pdb:2EKE|rcsb pdb:3PGE|rcsb pdb:3QHT|rcsb pdb:3TIX|rcsb pdb:3UF8|rcsb pdb:3UQA|rcsb pdb:3UQB|rcsb pdb:3V60|rcsb pdb:3V61|rcsb pdb:3V62|rcsb pdb:3VAW|rcsb pdb:4FN2|rcsb pdb:4G50|rcsb pdb:4GGQ|rcsb pdb:4GIV|rcsb pdb:5D6J|rcsb pdb:5JNE|rcsb pdb:5KLX|rcsb pdb:5V8T|rcsb pdb:5YC2|rcsb pdb:5YCA|rcsb pdb:6CFP|rcsb pdb:6P81|rcsb pdb:6Q2S|rcsb pdb:6RPQ|rcsb pdb:6UKM|rcsb pdb:6UKU|rcsb pdb:6UKV|rcsb pdb:6UKW|rcsb pdb:6UKX|rcsb pdb:6UKY|rcsb pdb:6UKZ|rcsb pdb:6UL0|rcsb pdb:6VEL|rcsb pdb:6VW2|rcsb pdb:7LTO|reactome:R-SCE-3065676|reactome:R-SCE-3065678|reactome:R-SCE-3065679|reactome:R-SCE-3108214|reactome:R-SCE-3108232|reactome:R-SCE-3232118|reactome:R-SCE-3899300|reactome:R-SCE-4085377|reactome:R-SCE-4551638|reactome:R-SCE-4570464|reactome:R-SCE-4615885|reactome:R-SCE-9615933|dip:DIP-1364N|mint:Q12306|sgd:YDR510W(identity)	-	isoform-comment:Major isoform.	crc64:A2790DE7F315E1A7	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:HrcogLANB///4vkSYtZ7OtzOb2k9606	rogid:oFdVBxN9WlDXTM7oAnv+1vfcXFQ559292	intact-crc:4F630D9CD6BE0F6C|rigid:HOaD121ckCVmS/vLXZOgjAJqeE8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:B0QYN7	uniprotkb:Q12306	intact:EBI-11525376|ensembl:ENSP00000384361	intact:EBI-17490|uniprotkb:D6VTD1|ensemblfungi:YDR510W	psi-mi:b0qyn7_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)	psi-mi:smt3_yeast(display_long)|uniprotkb:SMT3(gene name)|psi-mi:SMT3(display_short)|uniprotkb:D9719.15(orf name)|uniprotkb:YDR510W(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11547570|imex:IM-24995-2664	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_005255597.1|refseq:XP_005255598.1|refseq:XP_011520946.1|refseq:XP_011520947.1|ensembl:ENSG00000103275(gene)|ensembl:ENST00000402301(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0016740"(transferase activity)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|entrezgene/locuslink:7329(identity)	refseq:NP_010798.1|sgd:S000002918|ensemblfungi:YDR510W(gene)|ensemblfungi:YDR510W_mRNA(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005940"(septin ring)|go:"GO:0016925"(protein sumoylation)|go:"GO:0031386"(protein tag)|go:"GO:0042802"(identical protein binding)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR022617|interpro:IPR029071|rcsb pdb:1EUV|rcsb pdb:1L2N|rcsb pdb:2EKE|rcsb pdb:3PGE|rcsb pdb:3QHT|rcsb pdb:3TIX|rcsb pdb:3UF8|rcsb pdb:3UQA|rcsb pdb:3UQB|rcsb pdb:3V60|rcsb pdb:3V61|rcsb pdb:3V62|rcsb pdb:3VAW|rcsb pdb:4FN2|rcsb pdb:4G50|rcsb pdb:4GGQ|rcsb pdb:4GIV|rcsb pdb:5D6J|rcsb pdb:5JNE|rcsb pdb:5KLX|rcsb pdb:5V8T|rcsb pdb:5YC2|rcsb pdb:5YCA|rcsb pdb:6CFP|rcsb pdb:6P81|rcsb pdb:6Q2S|rcsb pdb:6RPQ|rcsb pdb:6UKM|rcsb pdb:6UKU|rcsb pdb:6UKV|rcsb pdb:6UKW|rcsb pdb:6UKX|rcsb pdb:6UKY|rcsb pdb:6UKZ|rcsb pdb:6UL0|rcsb pdb:6VEL|rcsb pdb:6VW2|rcsb pdb:7LTO|reactome:R-SCE-3065676|reactome:R-SCE-3065678|reactome:R-SCE-3065679|reactome:R-SCE-3108214|reactome:R-SCE-3108232|reactome:R-SCE-3232118|reactome:R-SCE-3899300|reactome:R-SCE-4085377|reactome:R-SCE-4551638|reactome:R-SCE-4570464|reactome:R-SCE-4615885|reactome:R-SCE-9615933|dip:DIP-1364N|mint:Q12306|sgd:YDR510W(identity)	-	-	crc64:A2790DE7F315E1A7	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:zMqQOA+nnCUquTIxAUwemkElTYI9606	rogid:oFdVBxN9WlDXTM7oAnv+1vfcXFQ559292	intact-crc:9CD09694D6F1413D|rigid:Ep+5f35Rf6pE50RcV2OoAY+y16Q	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9Y2D8	uniprotkb:Q12259	intact:EBI-2212028|uniprotkb:B4DFE3|uniprotkb:J3KR02|uniprotkb:A8K8W0|uniprotkb:D3DT13|uniprotkb:Q6P2P8|uniprotkb:Q6ULS1|uniprotkb:Q7L168|uniprotkb:Q9UIX0|intact:EBI-10964529|ensembl:ENSP00000340279	intact:EBI-30776|uniprotkb:D6VYA8|ensemblfungi:YLR108C	psi-mi:adip_human(display_long)|uniprotkb:SSX2IP(gene name)|psi-mi:SSX2IP(display_short)|uniprotkb:KIAA0923(gene name synonym)|uniprotkb:Afadin DIL domain-interacting protein(gene name synonym)|uniprotkb:SSX2-interacting protein(gene name synonym)	psi-mi:yl108_yeast(display_long)|uniprotkb:L2913(orf name)|uniprotkb:YLR108C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11547561|imex:IM-24995-2663	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011538912.1|refseq:NP_001159765.1|refseq:NP_001159766.1|refseq:NP_001159767.1|refseq:NP_001159889.1|refseq:NP_054740.3|refseq:XP_005270484.1|refseq:XP_005270485.1|refseq:XP_006710394.1|refseq:XP_016855723.1|ensembl:ENSG00000117155(gene)|ensembl:ENST00000342203(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005912"(adherens junction)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031252"(cell leading edge)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0035735"(intraciliary transport involved in cilium assembly)|go:"GO:0036064"(ciliary basal body)|go:"GO:0060271"(cilium assembly)|go:"GO:2000145"(regulation of cell motility)|interpro:IPR021622|mint:Q9Y2D8|entrezgene/locuslink:117178(identity)	refseq:NP_013209.1|sgd:S000004098|dip:DIP-4075N|ensemblfungi:YLR108C(gene)|ensemblfungi:YLR108C_mRNA(transcript)|go:"GO:0005634"(nucleus)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|sgd:YLR108C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:E0VeMRF9SrpQKSJFP01XEbMjeF89606	rogid:CzknxXhhvgMp3J0/oi197EgZ05U559292	intact-crc:997A35B09EB03972|rigid:1VHJ2RXiv00qeKbkVSavFpLhMM0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12259	uniprotkb:Q9UJV3-2	intact:EBI-30776|uniprotkb:D6VYA8|ensemblfungi:YLR108C	intact:EBI-10172526|ensembl:ENSP00000413976	psi-mi:yl108_yeast(display_long)|uniprotkb:L2913(orf name)|uniprotkb:YLR108C(locus name)	psi-mi:q9ujv3-2(display_long)|uniprotkb:RING-type E3 ubiquitin transferase MID2(gene name synonym)|uniprotkb:FXY2(gene name synonym)|uniprotkb:Midin-2(gene name synonym)|uniprotkb:Midline defect 2(gene name synonym)|uniprotkb:Midline-2(gene name synonym)|uniprotkb:RING finger protein 60(gene name synonym)|uniprotkb:RNF60(gene name synonym)|uniprotkb:TRIM1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 1(gene name synonym)|uniprotkb:MID2(gene name)|psi-mi:MID2(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11547550|imex:IM-24995-2662	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013209.1|sgd:S000004098|dip:DIP-4075N|ensemblfungi:YLR108C(gene)|ensemblfungi:YLR108C_mRNA(transcript)|go:"GO:0005634"(nucleus)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|sgd:YLR108C(identity)	intact:EBI-751983(isoform-parent)|uniprotkb:Q9UJV3-2(isoform-parent)|ensembl:ENSG00000080561(gene)|ensembl:ENST00000443968(transcript)|entrezgene/locuslink:11043(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:CzknxXhhvgMp3J0/oi197EgZ05U559292	rogid:/FJ+V2H7SaWon7caUWkEkmHFVxQ9606	intact-crc:35E2C4F45928B0DF|rigid:a7+6SPKWP0N9Pw7PFvF9AgHEh4w	false	-	sufficient binding region:21-705	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12259	uniprotkb:Q9P209	intact:EBI-30776|uniprotkb:D6VYA8|ensemblfungi:YLR108C	intact:EBI-739498|uniprotkb:Q9BV03|uniprotkb:Q9BWM3|uniprotkb:Q9NVR4|uniprotkb:B4DR26|ensembl:ENSP00000264935	psi-mi:yl108_yeast(display_long)|uniprotkb:L2913(orf name)|uniprotkb:YLR108C(locus name)	psi-mi:cep72_human(display_long)|uniprotkb:CEP72(gene name)|psi-mi:CEP72(display_short)|uniprotkb:KIAA1519(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11547539|imex:IM-24995-2661	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013209.1|sgd:S000004098|dip:DIP-4075N|ensemblfungi:YLR108C(gene)|ensemblfungi:YLR108C_mRNA(transcript)|go:"GO:0005634"(nucleus)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|sgd:YLR108C(identity)	refseq:NP_060610.2|ensembl:ENSG00000112877(gene)|ensembl:ENST00000264935(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007051"(spindle organization)|go:"GO:0007099"(centriole replication)|go:"GO:0033566"(gamma-tubulin complex localization)|go:"GO:0034451"(centriolar satellite)|go:"GO:1904779"(regulation of protein localization to centrosome)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR003603(U2A'/phosphoprotein 32 family A, C-terminal)|interpro:IPR032675|interpro:IPR040146|mint:Q9P209|reactome:R-HSA-2565942|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|refseq:XP_011512365.1|dip:DIP-54272N|entrezgene/locuslink:55722(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:CzknxXhhvgMp3J0/oi197EgZ05U559292	rogid:c00WdgE2iudiQUz3kXNZL5d0nuQ9606	intact-crc:CF73FEEBEE7A3477|rigid:ONT4emawE0Sz85EvUQeNZ2+b7Hg	false	-	sufficient binding region:190-647	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9HCK0	uniprotkb:Q12306	intact:EBI-3918996|ensembl:ENSP00000362758|ensembl:ENSP00000362760|uniprotkb:B3KQ53|uniprotkb:Q8WTR1	intact:EBI-17490|uniprotkb:D6VTD1|ensemblfungi:YDR510W	psi-mi:zbt26_human(display_long)|uniprotkb:ZBTB26(gene name)|psi-mi:ZBTB26(display_short)|uniprotkb:KIAA1572(gene name synonym)|uniprotkb:ZNF481(gene name synonym)|uniprotkb:Zinc finger protein 481(gene name synonym)|uniprotkb:Zinc finger protein Bioref(gene name synonym)	psi-mi:smt3_yeast(display_long)|uniprotkb:SMT3(gene name)|psi-mi:SMT3(display_short)|uniprotkb:D9719.15(orf name)|uniprotkb:YDR510W(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11547597|imex:IM-24995-2667	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000171448(gene)|ensembl:ENST00000373654(transcript)|ensembl:ENST00000373656(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|refseq:NP_001291292.1|refseq:NP_001291293.1|refseq:NP_065975.1|entrezgene/locuslink:57684(identity)	refseq:NP_010798.1|sgd:S000002918|ensemblfungi:YDR510W(gene)|ensemblfungi:YDR510W_mRNA(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005940"(septin ring)|go:"GO:0016925"(protein sumoylation)|go:"GO:0031386"(protein tag)|go:"GO:0042802"(identical protein binding)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR022617|interpro:IPR029071|rcsb pdb:1EUV|rcsb pdb:1L2N|rcsb pdb:2EKE|rcsb pdb:3PGE|rcsb pdb:3QHT|rcsb pdb:3TIX|rcsb pdb:3UF8|rcsb pdb:3UQA|rcsb pdb:3UQB|rcsb pdb:3V60|rcsb pdb:3V61|rcsb pdb:3V62|rcsb pdb:3VAW|rcsb pdb:4FN2|rcsb pdb:4G50|rcsb pdb:4GGQ|rcsb pdb:4GIV|rcsb pdb:5D6J|rcsb pdb:5JNE|rcsb pdb:5KLX|rcsb pdb:5V8T|rcsb pdb:5YC2|rcsb pdb:5YCA|rcsb pdb:6CFP|rcsb pdb:6P81|rcsb pdb:6Q2S|rcsb pdb:6RPQ|rcsb pdb:6UKM|rcsb pdb:6UKU|rcsb pdb:6UKV|rcsb pdb:6UKW|rcsb pdb:6UKX|rcsb pdb:6UKY|rcsb pdb:6UKZ|rcsb pdb:6UL0|rcsb pdb:6VEL|rcsb pdb:6VW2|rcsb pdb:7LTO|reactome:R-SCE-3065676|reactome:R-SCE-3065678|reactome:R-SCE-3065679|reactome:R-SCE-3108214|reactome:R-SCE-3108232|reactome:R-SCE-3232118|reactome:R-SCE-3899300|reactome:R-SCE-4085377|reactome:R-SCE-4551638|reactome:R-SCE-4570464|reactome:R-SCE-4615885|reactome:R-SCE-9615933|dip:DIP-1364N|mint:Q12306|sgd:YDR510W(identity)	-	-	crc64:A2790DE7F315E1A7	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:o5XKyl1Z7AtQOJH5HBqkYh5w1n89606	rogid:oFdVBxN9WlDXTM7oAnv+1vfcXFQ559292	intact-crc:CA33214C2A7F62E0|rigid:i8fjIddAhSTcipIKW5M/FEzX96I	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P63279	uniprotkb:Q12306	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	intact:EBI-17490|uniprotkb:D6VTD1|ensemblfungi:YDR510W	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:smt3_yeast(display_long)|uniprotkb:SMT3(gene name)|psi-mi:SMT3(display_short)|uniprotkb:D9719.15(orf name)|uniprotkb:YDR510W(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11547588|imex:IM-24995-2666	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N|entrezgene/locuslink:7329(identity)	refseq:NP_010798.1|sgd:S000002918|ensemblfungi:YDR510W(gene)|ensemblfungi:YDR510W_mRNA(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005940"(septin ring)|go:"GO:0016925"(protein sumoylation)|go:"GO:0031386"(protein tag)|go:"GO:0042802"(identical protein binding)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR022617|interpro:IPR029071|rcsb pdb:1EUV|rcsb pdb:1L2N|rcsb pdb:2EKE|rcsb pdb:3PGE|rcsb pdb:3QHT|rcsb pdb:3TIX|rcsb pdb:3UF8|rcsb pdb:3UQA|rcsb pdb:3UQB|rcsb pdb:3V60|rcsb pdb:3V61|rcsb pdb:3V62|rcsb pdb:3VAW|rcsb pdb:4FN2|rcsb pdb:4G50|rcsb pdb:4GGQ|rcsb pdb:4GIV|rcsb pdb:5D6J|rcsb pdb:5JNE|rcsb pdb:5KLX|rcsb pdb:5V8T|rcsb pdb:5YC2|rcsb pdb:5YCA|rcsb pdb:6CFP|rcsb pdb:6P81|rcsb pdb:6Q2S|rcsb pdb:6RPQ|rcsb pdb:6UKM|rcsb pdb:6UKU|rcsb pdb:6UKV|rcsb pdb:6UKW|rcsb pdb:6UKX|rcsb pdb:6UKY|rcsb pdb:6UKZ|rcsb pdb:6UL0|rcsb pdb:6VEL|rcsb pdb:6VW2|rcsb pdb:7LTO|reactome:R-SCE-3065676|reactome:R-SCE-3065678|reactome:R-SCE-3065679|reactome:R-SCE-3108214|reactome:R-SCE-3108232|reactome:R-SCE-3232118|reactome:R-SCE-3899300|reactome:R-SCE-4085377|reactome:R-SCE-4551638|reactome:R-SCE-4570464|reactome:R-SCE-4615885|reactome:R-SCE-9615933|dip:DIP-1364N|mint:Q12306|sgd:YDR510W(identity)	-	-	crc64:A2790DE7F315E1A7	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	rogid:oFdVBxN9WlDXTM7oAnv+1vfcXFQ559292	intact-crc:0C5192CAF0D63F30|rigid:9MPooZox+lbk1ZQnq+lAYhd58B0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8IYA8	uniprotkb:Q12329	intact:EBI-8638439|intact:EBI-28969497|ensembl:ENSP00000296449|ensembl:ENSP00000391788|ensembl:ENSP00000407837|uniprotkb:C9JJL0|uniprotkb:Q96LP7|intact:MINT-8162095|uniprotkb:Q05DG9	intact:EBI-8571|uniprotkb:D6VSF3|ensemblfungi:YDR171W	psi-mi:iho1_human(display_long)|uniprotkb:IHO1(gene name)|psi-mi:IHO1(display_short)|uniprotkb:CCDC36(gene name synonym)|uniprotkb:Cancer/testis antigen 74(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 36(gene name synonym)	psi-mi:hsp42_yeast(display_long)|uniprotkb:HSP42(gene name)|psi-mi:HSP42(display_short)|uniprotkb:YDR171W(locus name)|uniprotkb:YD9395.04(orf name)|uniprotkb:42 kDa heat shock protein(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11547664|imex:IM-24995-2674	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000296449|ensembl:ENST00000366429|ensembl:ENSP00000403700|ensembl:ENSP00000391788|ensembl:ENSP00000407837|ensembl:ENSG00000173421(gene)|ensembl:ENST00000296449(transcript)|ensembl:ENST00000438782(transcript)|ensembl:ENST00000452691(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0006310"(DNA recombination)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0042138"(meiotic DNA double-strand break formation)|go:"GO:0048477"(oogenesis)|go:"GO:0060629"(regulation of homologous chromosome segregation)|interpro:IPR031529|mint:Q8IYA8|refseq:XP_011531974.1|refseq:XP_011531975.1|refseq:NP_001128669.1|refseq:NP_835467.2|refseq:XP_006713187.1|entrezgene/locuslink:339834(identity)	refseq:NP_010456.1|sgd:S000002578|mint:Q12329|dip:DIP-2515N|ensemblfungi:YDR171W(gene)|ensemblfungi:YDR171W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0009408"(response to heat)|go:"GO:0009651"(response to salt stress)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043621"(protein self-association)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0140311"(protein sequestering activity)|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR031107|sgd:YDR171W(identity)	-	comment:mint	crc64:DF353A76493E3CE6	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:+TNQLExkhmC1NWqsE240Cx7zFVU9606	rogid:izvrv04fA3zcBqTeUeHD/erKGf4559292	intact-crc:95FEA896915C5157|rigid:e2BgtnOteZXZbtFm3URi4h2shDM	false	sufficient binding region:11-594	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12329	uniprotkb:Q5T124-6	intact:EBI-8571|uniprotkb:D6VSF3|ensemblfungi:YDR171W	intact:EBI-11524408	psi-mi:hsp42_yeast(display_long)|uniprotkb:HSP42(gene name)|psi-mi:HSP42(display_short)|uniprotkb:YDR171W(locus name)|uniprotkb:YD9395.04(orf name)|uniprotkb:42 kDa heat shock protein(gene name synonym)	psi-mi:q5t124-6(display_long)|uniprotkb:UBXN11(gene name)|psi-mi:UBXN11(display_short)|uniprotkb:Colorectal tumor-associated antigen COA-1(gene name synonym)|uniprotkb:SOC(gene name synonym)|uniprotkb:Socius(gene name synonym)|uniprotkb:UBX domain-containing protein 5(gene name synonym)|uniprotkb:UBXD5(gene name synonym)|uniprotkb:PP2243(orf name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11547655|imex:IM-24995-2673	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010456.1|sgd:S000002578|mint:Q12329|dip:DIP-2515N|ensemblfungi:YDR171W(gene)|ensemblfungi:YDR171W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0009408"(response to heat)|go:"GO:0009651"(response to salt stress)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043621"(protein self-association)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0140311"(protein sequestering activity)|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR031107|sgd:YDR171W(identity)	intact:EBI-746004(isoform-parent)|uniprotkb:Q5T124-6(isoform-parent)|entrezgene/locuslink:91544(identity)	-	crc64:DF353A76493E3CE6	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:izvrv04fA3zcBqTeUeHD/erKGf4559292	rogid:1YSjG/p2ihcjl4P8KdPCaX2HxiY9606	intact-crc:9B5DFC70D1F28835|rigid:6C7uPE50u2e0rlNYgtHYRIEau/I	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O15162	uniprotkb:Q12329	intact:EBI-740019|ensembl:ENSP00000345494|uniprotkb:B2R8H8|uniprotkb:B4DTE8	intact:EBI-8571|uniprotkb:D6VSF3|ensemblfungi:YDR171W	psi-mi:pls1_human(display_long)|uniprotkb:PLSCR1(gene name)|psi-mi:PLSCR1(display_short)|uniprotkb:"Ca(2+)-dependent phospholipid scramblase 1"(gene name synonym)|uniprotkb:Erythrocyte phospholipid scramblase(gene name synonym)|uniprotkb:MmTRA1b(gene name synonym)|uniprotkb:"Mg(2+)-dependent nuclease"(gene name synonym)	psi-mi:hsp42_yeast(display_long)|uniprotkb:HSP42(gene name)|psi-mi:HSP42(display_short)|uniprotkb:YDR171W(locus name)|uniprotkb:YD9395.04(orf name)|uniprotkb:42 kDa heat shock protein(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11547646|imex:IM-24995-2672	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000188313(gene)|ensembl:ENST00000342435(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001618"(virus receptor activity)|go:"GO:0003677"(DNA binding)|go:"GO:0004518"(nuclease activity)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006659"(phosphatidylserine biosynthetic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0006953"(acute-phase response)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010288"(response to lead ion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0017121"(plasma membrane phospholipid scrambling)|go:"GO:0017124"(SH3 domain binding)|ensembl:ENSP00000345494|ensembl:ENST00000448787|ensembl:ENSP00000411675|refseq:NP_066928.1|go:"GO:0017128"(phospholipid scramblase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030168"(platelet activation)|go:"GO:0032791"(lead ion binding)|go:"GO:0033003"(regulation of mast cell activation)|go:"GO:0035456"(response to interferon-beta)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0045340"(mercury ion binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0051607"(defense response to virus)|go:"GO:0060368"(regulation of Fc receptor mediated stimulatory signaling pathway)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070782"(phosphatidylserine exposure on apoptotic cell surface)|go:"GO:1905820"(positive regulation of chromosome separation)|go:"GO:2000373"("positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity")|interpro:IPR005552(Scramblase)|mint:O15162|rcsb pdb:1Y2A|refseq:XP_011511209.1|refseq:XP_011511206.1|refseq:XP_005247595.1|refseq:XP_011511208.1|refseq:XP_016862118.1|entrezgene/locuslink:5359(identity)	refseq:NP_010456.1|sgd:S000002578|mint:Q12329|dip:DIP-2515N|ensemblfungi:YDR171W(gene)|ensemblfungi:YDR171W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0009408"(response to heat)|go:"GO:0009651"(response to salt stress)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043621"(protein self-association)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0140311"(protein sequestering activity)|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR031107|sgd:YDR171W(identity)	-	-	crc64:DF353A76493E3CE6	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:XudfvUkrZbB28t9tpFkokgnDFGc9606	rogid:izvrv04fA3zcBqTeUeHD/erKGf4559292	intact-crc:179425350205A02F|rigid:DQ2v1ZTTgw4SkxNTVvVZCZA3UG0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12329	uniprotkb:A0A024R0Y4	intact:EBI-8571|uniprotkb:D6VSF3|ensemblfungi:YDR171W	intact:EBI-11523730|ensembl:ENSP00000477709|ensembl:ENSP00000478363|ensembl:ENSP00000481091	psi-mi:hsp42_yeast(display_long)|uniprotkb:HSP42(gene name)|psi-mi:HSP42(display_short)|uniprotkb:YDR171W(locus name)|uniprotkb:YD9395.04(orf name)|uniprotkb:42 kDa heat shock protein(gene name synonym)	psi-mi:a0a024r0y4_human(display_long)|uniprotkb:TADA2A(gene name)|psi-mi:TADA2A(display_short)|uniprotkb:TADA2L(gene name synonym)|uniprotkb:hCG_28187(orf name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11547637|imex:IM-24995-2671	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010456.1|sgd:S000002578|mint:Q12329|dip:DIP-2515N|ensemblfungi:YDR171W(gene)|ensemblfungi:YDR171W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0009408"(response to heat)|go:"GO:0009651"(response to salt stress)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043621"(protein self-association)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0140311"(protein sequestering activity)|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR031107|sgd:YDR171W(identity)	refseq:NP_001159577.2|refseq:NP_001479.4|ensembl:ENSG00000276234(gene)|ensembl:ENST00000612272(transcript)|ensembl:ENST00000615182(transcript)|ensembl:ENST00000620628(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031063"(regulation of histone deacetylation)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0035065"(regulation of histone acetylation)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090043"(regulation of tubulin deacetylation)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016827(Transcriptional adaptor 2)|interpro:IPR017884|interpro:IPR017930|interpro:IPR036388|interpro:IPR041983|interpro:IPR043145|entrezgene/locuslink:6871(identity)	-	crc64:DF353A76493E3CE6	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:izvrv04fA3zcBqTeUeHD/erKGf4559292	rogid:IGh7vC68gMLe+tAVGM4gc0rzc6Y9606	intact-crc:24EE09B89C12FEE9|rigid:AhFQF+UySGeUroxxo6tJBS1uzRk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q15911-2	uniprotkb:Q12318	intact:EBI-10237226|ensembl:ENSP00000438926	intact:EBI-37340|uniprotkb:D6VZ12|ensemblfungi:YLR376C	psi-mi:q15911-2(display_long)|uniprotkb:ZFHX3(gene name)|psi-mi:ZFHX3(display_short)|uniprotkb:AT motif-binding factor 1(gene name synonym)|uniprotkb:AT-binding transcription factor 1(gene name synonym)|uniprotkb:ATBF1(gene name synonym)|uniprotkb:Alpha-fetoprotein enhancer-binding protein(gene name synonym)|uniprotkb:Zinc finger homeodomain protein 3(gene name synonym)|uniprotkb:C16orf47(gene name synonym)	psi-mi:psy3_yeast(display_long)|uniprotkb:PSY3(gene name)|psi-mi:PSY3(display_short)|uniprotkb:L8039.17(orf name)|uniprotkb:YLR376C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11547626|imex:IM-24995-2670	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-2849611(isoform-parent)|uniprotkb:Q15911-2(isoform-parent)|ensembl:ENST00000397992(transcript)|ensembl:ENSG00000140836(gene)|entrezgene/locuslink:463(identity)	sgd:S000004368|refseq:NP_013480.1|dip:DIP-1903N|ensemblfungi:YLR376C(gene)|ensemblfungi:YLR376C_mRNA(transcript)|go:"GO:0000725"(recombinational repair)|go:"GO:0000730"(DNA recombinase assembly)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0035861"(site of double-strand break)|go:"GO:0070987"(error-free translesion synthesis)|go:"GO:0097196"(Shu complex)|interpro:IPR027417|interpro:IPR031779|rcsb pdb:3VU9|rcsb pdb:4DT1|rcsb pdb:4EQ6|rcsb pdb:5XYN|sgd:YLR376C(identity)	-	-	crc64:B652FD8113EB4C12	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:2SwbWXRFfxKEHEbo/SlMGw8/hPU9606	rogid:SlNKYcljv2UVV8YxX5/kVQJV/rU559292	intact-crc:20B96D55446E5144|rigid:lt0Ppo9sfiGTtecbUmGmPV8ZC3U	false	sufficient binding region:1-886	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12318	uniprotkb:O95751	intact:EBI-37340|uniprotkb:D6VZ12|ensemblfungi:YLR376C	intact:EBI-740738|ensembl:ENSP00000359557|uniprotkb:Q6IAR6	psi-mi:psy3_yeast(display_long)|uniprotkb:PSY3(gene name)|psi-mi:PSY3(display_short)|uniprotkb:L8039.17(orf name)|uniprotkb:YLR376C(locus name)	psi-mi:ldoc1_human(display_long)|uniprotkb:Leucine zipper protein down-regulated in cancer cells(gene name synonym)|uniprotkb:LDOC1(gene name)|psi-mi:LDOC1(display_short)|uniprotkb:BCUR1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11547617|imex:IM-24995-2669	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000004368|refseq:NP_013480.1|dip:DIP-1903N|ensemblfungi:YLR376C(gene)|ensemblfungi:YLR376C_mRNA(transcript)|go:"GO:0000725"(recombinational repair)|go:"GO:0000730"(DNA recombinase assembly)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0035861"(site of double-strand break)|go:"GO:0070987"(error-free translesion synthesis)|go:"GO:0097196"(Shu complex)|interpro:IPR027417|interpro:IPR031779|rcsb pdb:3VU9|rcsb pdb:4DT1|rcsb pdb:4EQ6|rcsb pdb:5XYN|sgd:YLR376C(identity)	refseq:NP_036449.1|ensembl:ENSG00000182195(gene)|ensembl:ENST00000370526(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071225"(cellular response to muramyl dipeptide)|interpro:IPR032549|interpro:IPR032567|entrezgene/locuslink:23641(identity)	-	crc64:B652FD8113EB4C12	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:SlNKYcljv2UVV8YxX5/kVQJV/rU559292	rogid:Ediu0oNiZ/+YVY8l3fNdgP5A+v09606	intact-crc:05A18ADB68E1AE8E|rigid:gF21nbpzGaPczRzexQEg3ER3Bnw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12318	uniprotkb:Q08379	intact:EBI-37340|uniprotkb:D6VZ12|ensemblfungi:YLR376C	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	psi-mi:psy3_yeast(display_long)|uniprotkb:PSY3(gene name)|psi-mi:PSY3(display_short)|uniprotkb:L8039.17(orf name)|uniprotkb:YLR376C(locus name)	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11547606|imex:IM-24995-2668	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000004368|refseq:NP_013480.1|dip:DIP-1903N|ensemblfungi:YLR376C(gene)|ensemblfungi:YLR376C_mRNA(transcript)|go:"GO:0000725"(recombinational repair)|go:"GO:0000730"(DNA recombinase assembly)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0035861"(site of double-strand break)|go:"GO:0070987"(error-free translesion synthesis)|go:"GO:0097196"(Shu complex)|interpro:IPR027417|interpro:IPR031779|rcsb pdb:3VU9|rcsb pdb:4DT1|rcsb pdb:4EQ6|rcsb pdb:5XYN|sgd:YLR376C(identity)	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N|entrezgene/locuslink:2801(identity)	-	crc64:B652FD8113EB4C12	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2017/05/26	rogid:SlNKYcljv2UVV8YxX5/kVQJV/rU559292	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	intact-crc:A18BE3AE85367305|rigid:Lplc7YMVYs7v4PVL6csSKfimvNM	false	-	sufficient binding region:383-1002	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9C040	uniprotkb:Q12341	intact:EBI-749840|uniprotkb:O60272|uniprotkb:Q9BSI9|uniprotkb:Q9UFZ1|ensembl:ENSP00000415812|ensembl:ENSP00000501586|ensembl:ENSP00000501612|ensembl:ENSP00000501652|ensembl:ENSP00000501662|ensembl:ENSP00000501792|ensembl:ENSP00000501822|ensembl:ENSP00000501951|ensembl:ENSP00000501994|ensembl:ENSP00000502089|ensembl:ENSP00000502114|ensembl:ENSP00000502159|ensembl:ENSP00000502273|ensembl:ENSP00000502348|ensembl:ENSP00000502356|ensembl:ENSP00000502519|ensembl:ENSP00000502543|ensembl:ENSP00000502676|uniprotkb:D3DP09	intact:EBI-8176|uniprotkb:Q6Q5I5|uniprotkb:D6W411|ensemblfungi:YPL001W	psi-mi:trim2_human(display_long)|uniprotkb:RING finger protein 86(gene name synonym)|uniprotkb:TRIM2(gene name)|psi-mi:TRIM2(display_short)|uniprotkb:KIAA0517(gene name synonym)|uniprotkb:RNF86(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM2(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase TRIM2(gene name synonym)	psi-mi:hat1_yeast(display_long)|uniprotkb:LPA16W(orf name)|uniprotkb:YP8132.12(orf name)|uniprotkb:HAT1(gene name)|psi-mi:HAT1(display_short)|uniprotkb:YPL001W(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11547713|imex:IM-24995-2679	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001123539.1|refseq:NP_056086.2|ensembl:ENST00000437508(transcript)|ensembl:ENST00000674874(transcript)|ensembl:ENST00000674876(transcript)|ensembl:ENSG00000109654(gene)|refseq:XP_016863433.1|refseq:XP_016863434.1|refseq:XP_016863437.1|refseq:XP_016863438.1|refseq:XP_016863439.1|refseq:XP_016863440.1|refseq:XP_016863441.1|ensembl:ENST00000674976(transcript)|ensembl:ENST00000675054(transcript)|ensembl:ENST00000675159(transcript)|ensembl:ENST00000675293(transcript)|ensembl:ENST00000675315(transcript)|ensembl:ENST00000675384(transcript)|ensembl:ENST00000675745(transcript)|ensembl:ENST00000675835(transcript)|ensembl:ENST00000676172(transcript)|ensembl:ENST00000676252(transcript)|ensembl:ENST00000676264(transcript)|ensembl:ENST00000676348(transcript)|ensembl:ENST00000676374(transcript)|ensembl:ENST00000676423(transcript)|ensembl:ENST00000676458(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017868|interpro:IPR017907|interpro:IPR027370|mint:Q9C040|rcsb pdb:7B2R|reactome:R-HSA-877300|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001258(NHL repeat)|interpro:IPR001298(Filamin/ABP280 repeat)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR013017(NHL repeat, subgroup)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|entrezgene/locuslink:23321(identity)	sgd:S000005922|refseq:NP_015324.1|mint:Q12341|dip:DIP-2362N|ensemblfungi:YPL001W(gene)|ensemblfungi:YPL001W_mRNA(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003682"(chromatin binding)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006348"|go:"GO:0010485"(H4 histone acetyltransferase activity)|go:"GO:0016573"(histone acetylation)|go:"GO:0042393"(histone binding)|go:"GO:0043967"(histone H4 acetylation)|interpro:IPR000182(GCN5-related N-acetyltransferase)|interpro:IPR013523(Histone acetyltransferase HAT1, C-terminal)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR017380(Histone acetyltransferase type B, catalytic subunit)|interpro:IPR019467|interpro:IPR037113|rcsb pdb:1BOB|rcsb pdb:4PSW|rcsb pdb:4PSX|reactome:R-SCE-3214847|sgd:YPL001W(identity)	-	-	crc64:8DECA134274413E6	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:vcyraMhX0YqrCi9PXhvlJ7QqhGs9606	rogid:IUMaZUpA1qs4/hc8K6ezZAIpQTY559292	intact-crc:75F397ECA3C50CEB|rigid:IMZDvVUmODZSsGzO/6xoJIj8o9w	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12329	uniprotkb:Q99750	intact:EBI-8571|uniprotkb:D6VSF3|ensemblfungi:YDR171W	intact:EBI-724076|ensembl:ENSP00000230321|ensembl:ENSP00000362142	psi-mi:hsp42_yeast(display_long)|uniprotkb:HSP42(gene name)|psi-mi:HSP42(display_short)|uniprotkb:YDR171W(locus name)|uniprotkb:YD9395.04(orf name)|uniprotkb:42 kDa heat shock protein(gene name synonym)	psi-mi:mdfi_human(display_long)|uniprotkb:Myogenic repressor I-mf(gene name synonym)|uniprotkb:MDFI(gene name)|psi-mi:MDFI(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11547704|imex:IM-24995-2678	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010456.1|sgd:S000002578|mint:Q12329|dip:DIP-2515N|ensemblfungi:YDR171W(gene)|ensemblfungi:YDR171W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0009408"(response to heat)|go:"GO:0009651"(response to salt stress)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043621"(protein self-association)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0140311"(protein sequestering activity)|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR031107|sgd:YDR171W(identity)	refseq:NP_005577.1|ensembl:ENSG00000112559(gene)|ensembl:ENST00000230321(transcript)|ensembl:ENST00000373051(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR026134|mint:Q99750|refseq:NP_001287733.1|refseq:NP_001287734.1|refseq:NP_001287735.1|entrezgene/locuslink:4188(identity)	-	crc64:DF353A76493E3CE6	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:izvrv04fA3zcBqTeUeHD/erKGf4559292	rogid:V3vU0fihMOW18DMHAiDbuZ3asNU9606	intact-crc:0A4129E73E5FD88A|rigid:1gAG+ma3vqbrFavwjVgrbasv7A8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96MA1	uniprotkb:Q12329	intact:EBI-954466|uniprotkb:Q96SD2|ensembl:ENSP00000360500	intact:EBI-8571|uniprotkb:D6VSF3|ensemblfungi:YDR171W	psi-mi:dmrtb_human(display_long)|uniprotkb:DMRTB1(gene name)|psi-mi:DMRTB1(display_short)	psi-mi:hsp42_yeast(display_long)|uniprotkb:HSP42(gene name)|psi-mi:HSP42(display_short)|uniprotkb:YDR171W(locus name)|uniprotkb:YD9395.04(orf name)|uniprotkb:42 kDa heat shock protein(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11547693|imex:IM-24995-2677	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|ensembl:ENSG00000143006(gene)|ensembl:ENST00000371445(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007281"(germ cell development)|go:"GO:0007548"(sex differentiation)|go:"GO:0046872"(metal ion binding)|interpro:IPR001275(DM DNA-binding)|interpro:IPR026607|interpro:IPR036407|mint:Q96MA1|refseq:NP_149056.1|ensembl:ENSP00000360500|entrezgene/locuslink:63948(identity)	refseq:NP_010456.1|sgd:S000002578|mint:Q12329|dip:DIP-2515N|ensemblfungi:YDR171W(gene)|ensemblfungi:YDR171W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0009408"(response to heat)|go:"GO:0009651"(response to salt stress)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043621"(protein self-association)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0140311"(protein sequestering activity)|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR031107|sgd:YDR171W(identity)	-	-	crc64:DF353A76493E3CE6	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:GU1xgsv/Oyy91PEorOlxBqAvIzc9606	rogid:izvrv04fA3zcBqTeUeHD/erKGf4559292	intact-crc:28403FAAB226D03F|rigid:uf8t2oK/UJIv8f9JHFrABaIU750	false	sufficient binding region:154-342	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96D09	uniprotkb:Q12329	intact:EBI-473189|ensembl:ENSP00000339057|ensembl:ENSP00000437394|ensembl:ENSP00000437872|ensembl:ENSP00000507692|ensembl:ENSP00000508139|uniprotkb:Q8NAB4|uniprotkb:D3DXA0	intact:EBI-8571|uniprotkb:D6VSF3|ensemblfungi:YDR171W	psi-mi:gasp2_human(display_long)|uniprotkb:GPRASP2(gene name)|psi-mi:GPRASP2(display_short)	psi-mi:hsp42_yeast(display_long)|uniprotkb:HSP42(gene name)|psi-mi:HSP42(display_short)|uniprotkb:YDR171W(locus name)|uniprotkb:YD9395.04(orf name)|uniprotkb:42 kDa heat shock protein(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11547684|imex:IM-24995-2676	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000158301(gene)|ensembl:ENST00000332262(transcript)|ensembl:ENST00000483720(transcript)|ensembl:ENST00000486814(transcript)|ensembl:ENST00000535209(transcript)|ensembl:ENST00000543253(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0061484"(hematopoietic stem cell homeostasis)|interpro:IPR006911(Protein of unknown function DUF634)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR043374|refseq:NP_001004051.1|refseq:NP_001171803.1|refseq:NP_001171804.1|refseq:NP_001171805.1|refseq:NP_001186747.1|refseq:NP_612446.1|entrezgene/locuslink:114928(identity)	refseq:NP_010456.1|sgd:S000002578|mint:Q12329|dip:DIP-2515N|ensemblfungi:YDR171W(gene)|ensemblfungi:YDR171W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0009408"(response to heat)|go:"GO:0009651"(response to salt stress)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043621"(protein self-association)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0140311"(protein sequestering activity)|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR031107|sgd:YDR171W(identity)	-	-	crc64:DF353A76493E3CE6	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:aUbvpCvGto1y4Rqnri7qaKaygQ89606	rogid:izvrv04fA3zcBqTeUeHD/erKGf4559292	intact-crc:5FB0E08EC2E4A2B5|rigid:BCJ58eKd4YPAhwvLi21UIAYmB3k	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12329	uniprotkb:Q8N9N5-2	intact:EBI-8571|uniprotkb:D6VSF3|ensemblfungi:YDR171W	intact:EBI-11524452|ensembl:ENSP00000347125	psi-mi:hsp42_yeast(display_long)|uniprotkb:HSP42(gene name)|psi-mi:HSP42(display_short)|uniprotkb:YDR171W(locus name)|uniprotkb:YD9395.04(orf name)|uniprotkb:42 kDa heat shock protein(gene name synonym)	psi-mi:q8n9n5-2(display_long)|uniprotkb:BANP(gene name)|psi-mi:BANP(display_short)|uniprotkb:BEN domain-containing protein 1(gene name synonym)|uniprotkb:BEND1(gene name synonym)|uniprotkb:Btg3-associated nuclear protein(gene name synonym)|uniprotkb:SMAR1(gene name synonym)|uniprotkb:Scaffold/matrix-associated region-1-binding protein(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11547675|imex:IM-24995-2675	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010456.1|sgd:S000002578|mint:Q12329|dip:DIP-2515N|ensemblfungi:YDR171W(gene)|ensemblfungi:YDR171W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0009408"(response to heat)|go:"GO:0009651"(response to salt stress)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043621"(protein self-association)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0140311"(protein sequestering activity)|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR031107|sgd:YDR171W(identity)	ensembl:ENSG00000172530(gene)|ensembl:ENST00000355022(transcript)|intact:EBI-744695(isoform-parent)|uniprotkb:Q8N9N5-2(isoform-parent)|entrezgene/locuslink:54971(identity)	-	crc64:DF353A76493E3CE6	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:izvrv04fA3zcBqTeUeHD/erKGf4559292	rogid:ESe6iCAhvq+i57fQHz3rGyg6UOo9606	intact-crc:FFA7BD4A45115CC8|rigid:qfKsJw/YTjkS/vwRcAEuCJNyM8o	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96BA8	uniprotkb:Q12382	intact:EBI-6942903|ensembl:ENSP00000481956|intact:MINT-268046|intact:MINT-8162577|uniprotkb:Q8N2D5|uniprotkb:Q96CP0	intact:EBI-36644|uniprotkb:D6W310|ensemblfungi:YOR311C	psi-mi:cr3l1_human(display_long)|uniprotkb:CREB3L1(gene name)|psi-mi:CREB3L1(display_short)|uniprotkb:OASIS(gene name synonym)|uniprotkb:PSEC0238(orf name)|uniprotkb:Old astrocyte specifically-induced substance(gene name synonym)	psi-mi:dgk1_yeast(display_long)|uniprotkb:High-copy suppressor of SLY1 defect protein 1(gene name synonym)|uniprotkb:DGK1(gene name)|psi-mi:DGK1(display_short)|uniprotkb:HSD1(gene name synonym)|uniprotkb:O6111(orf name)|uniprotkb:YOR311C(locus name)|uniprotkb:Diglyceride kinase 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11547767|imex:IM-24995-2685	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157613(gene)|ensembl:ENST00000621158(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0070278"(extracellular matrix constituent secretion)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029805|mint:Q96BA8|reactome:R-HSA-8874211|refseq:NP_443086.1|entrezgene/locuslink:90993(identity)	sgd:S000005838|refseq:NP_014956.3|dip:DIP-5021N|ensemblfungi:YOR311C(gene)|ensemblfungi:YOR311C_mRNA(transcript)|go:"GO:0004143"(diacylglycerol kinase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006654"(phosphatidic acid biosynthetic process)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:2001210"(regulation of isopentenyl diphosphate biosynthetic process, mevalonate pathway)|interpro:IPR037997|sgd:YOR311C(identity)	-	comment:mint|function:"Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE"	crc64:F8A0EE6F1018025B	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:sMWUFmBeBBCO+T0Y2CuB/un1lBg9606	rogid:/QKdWOYiwS8WsUTob40AL05Q9Hw559292	intact-crc:E5E638D13BCDD693|rigid:E1chp7hW5Yli2a5YmWKc7tCZS/4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8N6L0	uniprotkb:Q12382	intact:EBI-749265|uniprotkb:Q96MC3|ensembl:ENSP00000404220	intact:EBI-36644|uniprotkb:D6W310|ensemblfungi:YOR311C	psi-mi:kash5_human(display_long)|uniprotkb:KASH5(gene name)|psi-mi:KASH5(display_short)|uniprotkb:CCDC155(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 155(gene name synonym)|uniprotkb:KASH domain-containing protein 5(gene name synonym)	psi-mi:dgk1_yeast(display_long)|uniprotkb:High-copy suppressor of SLY1 defect protein 1(gene name synonym)|uniprotkb:DGK1(gene name)|psi-mi:DGK1(display_short)|uniprotkb:HSD1(gene name synonym)|uniprotkb:O6111(orf name)|uniprotkb:YOR311C(locus name)|uniprotkb:Diglyceride kinase 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11547758|imex:IM-24995-2684	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_653289.3|ensembl:ENSG00000161609(gene)|ensembl:ENST00000447857(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034397"(telomere localization)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051225"(spindle assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0090172"(microtubule cytoskeleton organization involved in homologous chromosome segregation)|go:"GO:0090220"(chromosome localization to nuclear envelope involved in homologous chromosome segregation)|go:"GO:0090619"(meiotic spindle pole)|interpro:IPR011992(EF-Hand type)|interpro:IPR028168|interpro:IPR028170|interpro:IPR039508|mint:Q8N6L0|rcsb pdb:6R2I|rcsb pdb:6WMF|entrezgene/locuslink:147872(identity)	sgd:S000005838|refseq:NP_014956.3|dip:DIP-5021N|ensemblfungi:YOR311C(gene)|ensemblfungi:YOR311C_mRNA(transcript)|go:"GO:0004143"(diacylglycerol kinase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006654"(phosphatidic acid biosynthetic process)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:2001210"(regulation of isopentenyl diphosphate biosynthetic process, mevalonate pathway)|interpro:IPR037997|sgd:YOR311C(identity)	-	-	crc64:F8A0EE6F1018025B	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Wl9L7AcvDHCZuKjYLn8QgGIbZTc9606	rogid:/QKdWOYiwS8WsUTob40AL05Q9Hw559292	intact-crc:A0A699FFA7EFEE09|rigid:8uCgzyVNpSfPr0geC3hoJ0hbNeA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49760-3	uniprotkb:Q12380	intact:EBI-11535445|ensembl:ENSP00000354856|ensembl:ENSP00000459461	intact:EBI-2664|uniprotkb:D6W3M0|ensemblfungi:YPL149W	psi-mi:p49760-3(display_long)|uniprotkb:CDC-like kinase 2(gene name synonym)|uniprotkb:CLK2(gene name)|psi-mi:CLK2(display_short)	psi-mi:atg5_yeast(display_long)|uniprotkb:ATG5(gene name)|psi-mi:ATG5(display_short)|uniprotkb:APG5(gene name synonym)|uniprotkb:YPL149W(locus name)|uniprotkb:P2601(orf name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11547749|imex:IM-24995-2683	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-750020(isoform-parent)|ensembl:ENSG00000176444(gene)|ensembl:ENSG00000261893(gene)|ensembl:ENST00000361168(transcript)|ensembl:ENST00000572269(transcript)|uniprotkb:P49760-3(isoform-parent)|entrezgene/locuslink:1196(identity)	refseq:NP_015176.1|sgd:S000006070|reactome:R-SCE-1632852|dip:DIP-1195N|reactome:R-SCE-8934903|ensemblfungi:YPL149W(gene)|ensemblfungi:YPL149W_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005634"(nucleus)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0006501"(C-terminal protein lipidation)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016020"(membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0016787"(hydrolase activity)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034274"(Atg12-Atg5-Atg16 complex)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044804"(autophagy of nucleus)|go:"GO:0044805"(late nucleophagy)|go:"GO:0061908"(phagophore)|go:"GO:0061912"(selective autophagy)|go:"GO:0120095"(vacuole-isolation membrane contact site)|go:"GO:0140355"(cargo receptor ligand activity)|interpro:IPR007239(Autophagy protein 5)|interpro:IPR042526|interpro:IPR042527|rcsb pdb:2DYM|rcsb pdb:2DYO|rcsb pdb:3W1S|sgd:YPL149W(identity)	-	-	crc64:BE513A631DEAA0A1	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:wFw4PjPFbFOw5k9Fqay3nAen8ZI9606	rogid:PMSbzCApcY0S518yzmdDm3bPY74559292	intact-crc:4DED761F17B2E483|rigid:5tumTh+hsOZZ9hC+VgM3hQfs+Qg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12354	uniprotkb:Q8WZ19	intact:EBI-37732|uniprotkb:D6VYB6|ensemblfungi:YLR118C	intact:EBI-742916|ensembl:ENSP00000311202|ensembl:ENSP00000455785|uniprotkb:Q96P93|uniprotkb:Q96SA1|uniprotkb:A8K0R5	psi-mi:apth1_yeast(display_long)|uniprotkb:L2955(orf name)|uniprotkb:YLR118C(locus name)	psi-mi:bacd1_human(display_long)|uniprotkb:Polymerase delta-interacting protein 1(gene name synonym)|uniprotkb:TNFAIP1-like protein(gene name synonym)|uniprotkb:KCTD13(gene name)|psi-mi:KCTD13(display_short)|uniprotkb:PDIP1(gene name synonym)|uniprotkb:POLDIP1(gene name synonym)|uniprotkb:FKSG86(orf name)|uniprotkb:PP6832(orf name)|uniprotkb:BACURD1(gene name synonym)|uniprotkb:BTB/POZ domain-containing protein KCTD13(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11547740|imex:IM-24995-2682	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013219.1|sgd:S000004108|reactome:R-SCE-203615|dip:DIP-2830N|reactome:R-SCE-9648002|ensemblfungi:YLR118C(gene)|ensemblfungi:YLR118C_mRNA(transcript)|go:"GO:0002084"(protein depalmitoylation)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0008474"("palmitoyl-(protein) hydrolase activity")|go:"GO:0035601"(protein deacylation)|go:"GO:0052689"(carboxylic ester hydrolase activity)|interpro:IPR003140(Phospholipase/carboxylesterase)|interpro:IPR029058|sgd:YLR118C(identity)	refseq:NP_849194.1|ensembl:ENSG00000174943(gene)|ensembl:ENST00000308768(transcript)|ensembl:ENST00000568000(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016477"(cell migration)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0043149"(stress fiber assembly)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0050806"(positive regulation of synaptic transmission)|go:"GO:0051260"(protein homooligomerization)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR003131(Potassium channel, voltage dependent, Kv,  tetramerisation)|interpro:IPR011333(BTB/POZ fold)|mint:Q8WZ19|rcsb pdb:4UIJ|reactome:R-HSA-9696264|reactome:R-HSA-9696270|entrezgene/locuslink:253980(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:z4WO9062CHwiLV2c1/+N6zn0AEE559292	rogid:hAH5yJEoda0H1anmnSXWHO0o1ZM9606	intact-crc:7D5E1CF003D2E811|rigid:sbZUfm+kDbyU4Pw91svZXTROBu0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12354	uniprotkb:Q5JST6	intact:EBI-37732|uniprotkb:D6VYB6|ensemblfungi:YLR118C	intact:EBI-2349927|uniprotkb:Q9H653|uniprotkb:Q5JST8|uniprotkb:Q68DK4|uniprotkb:Q8NEI0|intact:EBI-28971886|ensembl:ENSP00000404232	psi-mi:apth1_yeast(display_long)|uniprotkb:L2955(orf name)|uniprotkb:YLR118C(locus name)	psi-mi:efhc2_human(display_long)|uniprotkb:EFHC2(gene name)|psi-mi:EFHC2(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11547731|imex:IM-24995-2681	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013219.1|sgd:S000004108|reactome:R-SCE-203615|dip:DIP-2830N|reactome:R-SCE-9648002|ensemblfungi:YLR118C(gene)|ensemblfungi:YLR118C_mRNA(transcript)|go:"GO:0002084"(protein depalmitoylation)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0008474"("palmitoyl-(protein) hydrolase activity")|go:"GO:0035601"(protein deacylation)|go:"GO:0052689"(carboxylic ester hydrolase activity)|interpro:IPR003140(Phospholipase/carboxylesterase)|interpro:IPR029058|sgd:YLR118C(identity)	ensembl:ENSP00000404232|refseq:NP_079460.2|ensembl:ENSG00000183690(gene)|ensembl:ENST00000420999(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005930"(axoneme)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0060285"(cilium-dependent cell motility)|go:"GO:0072686"(mitotic spindle)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR006602(Region of unknown function DM10)|interpro:IPR011992(EF-Hand type)|interpro:IPR040193|rcsb pdb:2Z13|rcsb pdb:2Z14|entrezgene/locuslink:80258(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:z4WO9062CHwiLV2c1/+N6zn0AEE559292	rogid:O1XriQSkLcYkk7H7AlanQ1FKIBY9606	intact-crc:900225051D503448|rigid:ERsx6GWfLx/Ylwy0BOdDl5+83hc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12342	uniprotkb:Q13137	intact:EBI-38872|uniprotkb:D6VRK2|ensemblfungi:YDL146W	intact:EBI-739580|uniprotkb:B4DDC4|uniprotkb:E7ENK0|uniprotkb:Q53FQ5|uniprotkb:Q53HB5|uniprotkb:Q6IBN9|uniprotkb:Q9BTF7|uniprotkb:B2RBT0|ensembl:ENSP00000258947|uniprotkb:B4E0C0|uniprotkb:E7ETP5|uniprotkb:B4DDT4|uniprotkb:B4DP36|uniprotkb:E9PBE5	psi-mi:ldb17_yeast(display_long)|uniprotkb:Low dye-binding protein 17(gene name synonym)|uniprotkb:LDB17(gene name)|psi-mi:LDB17(display_short)|uniprotkb:D1575(orf name)|uniprotkb:YDL146W(locus name)	psi-mi:caco2_human(display_long)|uniprotkb:CALCOCO2(gene name)|psi-mi:CALCOCO2(display_short)|uniprotkb:NDP52(gene name synonym)|uniprotkb:Nuclear domain 10 protein NDP52(gene name synonym)|uniprotkb:Antigen nuclear dot 52 kDa protein(gene name synonym)|uniprotkb:Nuclear dot protein 52(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11547722|imex:IM-24995-2680	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010135.1|sgd:S000002305|dip:DIP-1803N|ensemblfungi:YDL146W(gene)|ensemblfungi:YDL146W_mRNA(transcript)|go:"GO:0000147"(actin cortical patch assembly)|go:"GO:0005737"(cytoplasm)|go:"GO:0005933"(cellular bud)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006897"(endocytosis)|go:"GO:0017022"(myosin binding)|go:"GO:0030479"(actin cortical patch)|go:"GO:0051666"(actin cortical patch localization)|go:"GO:0071933"(Arp2/3 complex binding)|interpro:IPR018556|interpro:IPR030125|sgd:YDL146W(identity)	refseq:NP_001248319.1|refseq:NP_001248320.1|refseq:NP_001248322.1|refseq:NP_005822.1|ensembl:ENSG00000136436(gene)|ensembl:ENST00000258947(transcript)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016032"(viral process)|go:"GO:0016605"(PML body)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0098792"(xenophagy)|go:"GO:1901098"(positive regulation of autophagosome maturation)|interpro:IPR041611|interpro:IPR041641|mint:Q13137|rcsb pdb:2MXP|rcsb pdb:3VVV|rcsb pdb:3VVW|rcsb pdb:4GXL|rcsb pdb:4HAN|rcsb pdb:4XKL|rcsb pdb:5AAQ|rcsb pdb:5Z7A|rcsb pdb:5Z7L|refseq:NP_001248324.1|dip:DIP-57534N|entrezgene/locuslink:10241(identity)	-	crc64:608DED6598F054BD	crc64:609B121DA1A9DCB8	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:o1oe+zL8FJ90xm43hCM9A7lGCjI559292	rogid:N/GPJUGBK+Dh5Cg+csmafphuo9M9606	intact-crc:41CFEE631C67834E|rigid:VVJMZbTKuZ9FvwMTkTANwYJt7ww	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12439	uniprotkb:P63279	intact:EBI-2342872|uniprotkb:D6W2Q1	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	psi-mi:yo21a_yeast(display_long)|uniprotkb:TY2A-OR1(gene name)|psi-mi:TY2A-OR1(display_short)|uniprotkb:YORCTy2-1 GAG(gene name synonym)|uniprotkb:O4787(orf name)|uniprotkb:YOR192C-A(locus name)	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11547832|imex:IM-24995-2692	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000007353|interpro:IPR015820(Retrotransposon Ty1 A, N-terminal)|refseq:NP_058186.1|go:"GO:0000943"(retrotransposon nucleocapsid)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0032197"(transposition, RNA-mediated)|sgd:YOR192C-A(identity)	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N|entrezgene/locuslink:7329(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:IbfwV+zl9+6yPnQgzLPL0tLgx5s559292	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	intact-crc:84B20B0DD1A8EA85|rigid:mwSLHioTwi1SSdJjPRevAC+8v9o	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O75928-2	uniprotkb:Q12439	intact:EBI-348567|ensembl:ENSP00000317163|intact:EBI-7259183|intact:MINT-1455402	intact:EBI-2342872|uniprotkb:D6W2Q1	psi-mi:o75928-2(display_long)|uniprotkb:Msx-interacting zinc finger protein(gene name synonym)|uniprotkb:PIAS-NY protein(gene name synonym)|uniprotkb:Protein inhibitor of activated STAT x(gene name synonym)|uniprotkb:Protein inhibitor of activated STAT2(gene name synonym)|uniprotkb:PIAS2(gene name)|psi-mi:PIAS2(display_short)|uniprotkb:PIASX(gene name synonym)|uniprotkb:Androgen receptor-interacting protein 3(gene name synonym)|uniprotkb:DAB2-interacting protein(gene name synonym)|uniprotkb:PIASx-alpha(isoform synonym)|uniprotkb:ARIP3(isoform synonym)|uniprotkb:E3 SUMO-protein transferase PIAS2(gene name synonym)	psi-mi:yo21a_yeast(display_long)|uniprotkb:TY2A-OR1(gene name)|psi-mi:TY2A-OR1(display_short)|uniprotkb:YORCTy2-1 GAG(gene name synonym)|uniprotkb:O4787(orf name)|uniprotkb:YOR192C-A(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11547823|imex:IM-24995-2691	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-348555(pias2_human)|ensembl:ENSG00000078043(gene)|ensembl:ENST00000324794(transcript)|uniprotkb:O75928-2(isoform-parent)|entrezgene/locuslink:9063(identity)	sgd:S000007353|interpro:IPR015820(Retrotransposon Ty1 A, N-terminal)|refseq:NP_058186.1|go:"GO:0000943"(retrotransposon nucleocapsid)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0032197"(transposition, RNA-mediated)|sgd:YOR192C-A(identity)	-	isoform-comment:"Contains a glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) at position 562."	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:JNC3UGf8YuVcrXbFnO27d4orf4I9606	rogid:IbfwV+zl9+6yPnQgzLPL0tLgx5s559292	intact-crc:D2FD28E01D1AC3E5|rigid:7gCJHwxB2mFvsGjlOGmatiloMro	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O14641	uniprotkb:Q12439	intact:EBI-740850|ensembl:ENSP00000005340|uniprotkb:Q53XM0|uniprotkb:D3DTN3	intact:EBI-2342872|uniprotkb:D6W2Q1	psi-mi:dvl2_human(display_long)|uniprotkb:DSH homolog 2(gene name synonym)|uniprotkb:DVL2(gene name)|psi-mi:DVL2(display_short)	psi-mi:yo21a_yeast(display_long)|uniprotkb:TY2A-OR1(gene name)|psi-mi:TY2A-OR1(display_short)|uniprotkb:YORCTy2-1 GAG(gene name synonym)|uniprotkb:O4787(orf name)|uniprotkb:YOR192C-A(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11547814|imex:IM-24995-2690	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004413.1|ensembl:ENSG00000004975(gene)|ensembl:ENST00000005340(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005109"(frizzled binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0007507"(heart development)|go:"GO:0016235"(aggresome)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044340"(canonical Wnt signaling pathway involved in regulation of cell proliferation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0150012"(positive regulation of neuron projection arborization)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008341(Dishevelled-2 region)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:O14641|rcsb pdb:2REY|rcsb pdb:3CBX|rcsb pdb:3CBY|rcsb pdb:3CBZ|rcsb pdb:3CC0|rcsb pdb:4WIP|rcsb pdb:5LNP|rcsb pdb:5SUY|rcsb pdb:5SUZ|rcsb pdb:6IW3|rcsb pdb:6JCK|reactome:R-HSA-201681|reactome:R-HSA-201688|reactome:R-HSA-2028269|reactome:R-HSA-4086400|reactome:R-HSA-4608870|reactome:R-HSA-4641258|reactome:R-HSA-4641262|reactome:R-HSA-5099900|reactome:R-HSA-5368598|reactome:R-HSA-5663220|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9673324|ensembl:ENSP00000005340|dip:DIP-34433N|entrezgene/locuslink:1856(identity)	sgd:S000007353|interpro:IPR015820(Retrotransposon Ty1 A, N-terminal)|refseq:NP_058186.1|go:"GO:0000943"(retrotransposon nucleocapsid)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0032197"(transposition, RNA-mediated)|sgd:YOR192C-A(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:2Vdc8oRnT4Mz/j+EXQXrL3AszOc9606	rogid:IbfwV+zl9+6yPnQgzLPL0tLgx5s559292	intact-crc:FF8B2A706C09F8F8|rigid:yfRPz+N95NdSBBchwTwQi26ibj4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12431	uniprotkb:Q8N6L0	intact:EBI-2345238|uniprotkb:D6VXY8|ensemblfungi:YLL014W	intact:EBI-749265|uniprotkb:Q96MC3|ensembl:ENSP00000404220	psi-mi:emc6_yeast(display_long)|uniprotkb:L1321(orf name)|uniprotkb:YLL014W(locus name)|uniprotkb:EMC6(gene name)|psi-mi:EMC6(display_short)	psi-mi:kash5_human(display_long)|uniprotkb:KASH5(gene name)|psi-mi:KASH5(display_short)|uniprotkb:CCDC155(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 155(gene name synonym)|uniprotkb:KASH domain-containing protein 5(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11547805|imex:IM-24995-2689	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003937|refseq:NP_013087.1|dip:DIP-988N|ensemblfungi:YLL014W(gene)|ensemblfungi:YLL014W_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0072546"(EMC complex)|interpro:IPR029008|rcsb pdb:6WB9|rcsb pdb:7KRA|rcsb pdb:7KTX|sgd:YLL014W(identity)	refseq:NP_653289.3|ensembl:ENSG00000161609(gene)|ensembl:ENST00000447857(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034397"(telomere localization)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051225"(spindle assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0090172"(microtubule cytoskeleton organization involved in homologous chromosome segregation)|go:"GO:0090220"(chromosome localization to nuclear envelope involved in homologous chromosome segregation)|go:"GO:0090619"(meiotic spindle pole)|interpro:IPR011992(EF-Hand type)|interpro:IPR028168|interpro:IPR028170|interpro:IPR039508|mint:Q8N6L0|rcsb pdb:6R2I|rcsb pdb:6WMF|entrezgene/locuslink:147872(identity)	-	crc64:36C316F18156823E	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:eDM+DjV86zLNJ9eE07m60y7HWSI559292	rogid:Wl9L7AcvDHCZuKjYLn8QgGIbZTc9606	intact-crc:1C220A2AA86F39B2|rigid:YiShuBqvKw76aSAZ7VNzTxqvKJI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12417	uniprotkb:O94972	intact:EBI-710|uniprotkb:D6W3L8|ensemblfungi:YPL151C	intact:EBI-741602|uniprotkb:Q7Z3E6|uniprotkb:Q8IYF7|uniprotkb:Q8WYF7|intact:EBI-28976055|ensembl:ENSP00000262294|ensembl:ENSP00000376785|uniprotkb:A8K0V9|uniprotkb:A8K8U4|uniprotkb:A8MZ79|uniprotkb:B4DGZ3|uniprotkb:F8WEE6	psi-mi:prp46_yeast(display_long)|uniprotkb:CWC1(gene name synonym)|uniprotkb:PRP nineteen-associated complex protein 50(gene name synonym)|uniprotkb:PRP19-associated complex protein 50(gene name synonym)|uniprotkb:P2594(orf name)|uniprotkb:YPL151C(locus name)|uniprotkb:PRP46(gene name)|psi-mi:PRP46(display_short)|uniprotkb:NTC50(gene name synonym)|uniprotkb:Pre-mRNA-processing protein 46(gene name synonym)|uniprotkb:Complexed with CEF1 protein 1(gene name synonym)	psi-mi:tri37_human(display_long)|uniprotkb:Mulibrey nanism protein(gene name synonym)|uniprotkb:TRIM37(gene name)|psi-mi:TRIM37(display_short)|uniprotkb:KIAA0898(gene name synonym)|uniprotkb:MUL(gene name synonym)|uniprotkb:POB1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 37(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM37(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11547796|imex:IM-24995-2688	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015174.1|sgd:S000006072|ensemblfungi:YPL151C(gene)|ensemblfungi:YPL151C_mRNA(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000974"(Prp19 complex)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|dip:DIP-3994N|mint:Q12417|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|sgd:YPL151C(identity)	refseq:NP_001005207.1|refseq:NP_056109.1|refseq:NP_001307916.1|ensembl:ENSP00000262294|ensembl:ENST00000393065|ensembl:ENSP00000376784|ensembl:ENSP00000376785|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046600"(negative regulation of centriole replication)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070842"(aggresome assembly)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002083(MATH)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR008974(TRAF-like)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR037299|rcsb pdb:3LRQ|reactome:R-HSA-983168|ensembl:ENSG00000108395(gene)|ensembl:ENST00000262294(transcript)|ensembl:ENST00000393066(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005777"(peroxisome)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016235"(aggresome)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0035518"(histone H2A monoubiquitination)|refseq:NP_001307919.1|dip:DIP-34437N|entrezgene/locuslink:4591(identity)	-	crc64:0E888F566A5414BD	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:016ynVER9V3d44NwkqRG7TIvf9w559292	rogid:y2njeO0MUBrKU9MUvkbo1uZmqkE9606	intact-crc:636576FFBCAF5FB0|rigid:KNoTEP3FRmEm2D+VOCvUV7vagdM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12417	uniprotkb:Q08379	intact:EBI-710|uniprotkb:D6W3L8|ensemblfungi:YPL151C	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	psi-mi:prp46_yeast(display_long)|uniprotkb:CWC1(gene name synonym)|uniprotkb:PRP nineteen-associated complex protein 50(gene name synonym)|uniprotkb:PRP19-associated complex protein 50(gene name synonym)|uniprotkb:P2594(orf name)|uniprotkb:YPL151C(locus name)|uniprotkb:PRP46(gene name)|psi-mi:PRP46(display_short)|uniprotkb:NTC50(gene name synonym)|uniprotkb:Pre-mRNA-processing protein 46(gene name synonym)|uniprotkb:Complexed with CEF1 protein 1(gene name synonym)	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11547785|imex:IM-24995-2687	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015174.1|sgd:S000006072|ensemblfungi:YPL151C(gene)|ensemblfungi:YPL151C_mRNA(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000974"(Prp19 complex)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|dip:DIP-3994N|mint:Q12417|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|sgd:YPL151C(identity)	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N|entrezgene/locuslink:2801(identity)	-	crc64:0E888F566A5414BD	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2017/05/26	rogid:016ynVER9V3d44NwkqRG7TIvf9w559292	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	intact-crc:8D40A3676E203096|rigid:gKJm6NwORNiNROLKTG4Oi1gRKiY	false	-	sufficient binding region:383-1002	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12389	uniprotkb:O14641	intact:EBI-5644|uniprotkb:D6VRW1|ensemblfungi:YDL031W	intact:EBI-740850|ensembl:ENSP00000005340|uniprotkb:Q53XM0|uniprotkb:D3DTN3	psi-mi:dbp10_yeast(display_long)|uniprotkb:DBP10(gene name)|psi-mi:DBP10(display_short)|uniprotkb:YDL031W(locus name)|uniprotkb:D2770(orf name)|uniprotkb:DEAD box protein 10(gene name synonym)	psi-mi:dvl2_human(display_long)|uniprotkb:DSH homolog 2(gene name synonym)|uniprotkb:DVL2(gene name)|psi-mi:DVL2(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11547776|imex:IM-24995-2686	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010253.2|sgd:S000002189|dip:DIP-6387N|mint:Q12389|ensemblfungi:YDL031W(gene)|ensemblfungi:YDL031W_mRNA(transcript)|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000466"("maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0042802"(identical protein binding)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902626"(assembly of large subunit precursor of preribosome)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR012541(DBP10CT)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|interpro:IPR033517|sgd:YDL031W(identity)	refseq:NP_004413.1|ensembl:ENSG00000004975(gene)|ensembl:ENST00000005340(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005109"(frizzled binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0007507"(heart development)|go:"GO:0016235"(aggresome)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044340"(canonical Wnt signaling pathway involved in regulation of cell proliferation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0150012"(positive regulation of neuron projection arborization)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008341(Dishevelled-2 region)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:O14641|rcsb pdb:2REY|rcsb pdb:3CBX|rcsb pdb:3CBY|rcsb pdb:3CBZ|rcsb pdb:3CC0|rcsb pdb:4WIP|rcsb pdb:5LNP|rcsb pdb:5SUY|rcsb pdb:5SUZ|rcsb pdb:6IW3|rcsb pdb:6JCK|reactome:R-HSA-201681|reactome:R-HSA-201688|reactome:R-HSA-2028269|reactome:R-HSA-4086400|reactome:R-HSA-4608870|reactome:R-HSA-4641258|reactome:R-HSA-4641262|reactome:R-HSA-5099900|reactome:R-HSA-5368598|reactome:R-HSA-5663220|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9673324|ensembl:ENSP00000005340|dip:DIP-34433N|entrezgene/locuslink:1856(identity)	-	crc64:0533013C276095DF	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:PHnLvx2Kk2uAkF21YkvqyoJqTWg559292	rogid:2Vdc8oRnT4Mz/j+EXQXrL3AszOc9606	intact-crc:31B161219B2B7CC0|rigid:hCU0PErWfmZc22HNiL+Lm8Gk1Zk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12476	uniprotkb:O14641	intact:EBI-31475|uniprotkb:D6VRH7|ensemblfungi:YDL175C	intact:EBI-740850|ensembl:ENSP00000005340|uniprotkb:Q53XM0|uniprotkb:D3DTN3	psi-mi:air2_yeast(display_long)|uniprotkb:Arginine methyltransferase-interacting RING finger protein 2(gene name synonym)|uniprotkb:AIR2(gene name)|psi-mi:AIR2(display_short)|uniprotkb:YDL175C(locus name)	psi-mi:dvl2_human(display_long)|uniprotkb:DSH homolog 2(gene name synonym)|uniprotkb:DVL2(gene name)|psi-mi:DVL2(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11547895|imex:IM-24995-2699	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010106.1|sgd:S000002334|dip:DIP-2543N|mint:Q12476|ensemblfungi:YDL175C(gene)|ensemblfungi:YDL175C_mRNA(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0006400"(tRNA modification)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031499"(TRAMP complex)|go:"GO:0043629"(ncRNA polyadenylation)|go:"GO:0071031"(nuclear mRNA surveillance of mRNA 3'-end processing)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071036"(nuclear polyadenylation-dependent snoRNA catabolic process)|go:"GO:0071037"(nuclear polyadenylation-dependent snRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071039"(nuclear polyadenylation-dependent CUT catabolic process)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR016713("Poly(A) polymerase complex, Air1/2")|interpro:IPR036875|rcsb pdb:2LLI|rcsb pdb:3NYB|rcsb pdb:4U4C|sgd:YDL175C(identity)	refseq:NP_004413.1|ensembl:ENSG00000004975(gene)|ensembl:ENST00000005340(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005109"(frizzled binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0007507"(heart development)|go:"GO:0016235"(aggresome)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044340"(canonical Wnt signaling pathway involved in regulation of cell proliferation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0150012"(positive regulation of neuron projection arborization)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008341(Dishevelled-2 region)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:O14641|rcsb pdb:2REY|rcsb pdb:3CBX|rcsb pdb:3CBY|rcsb pdb:3CBZ|rcsb pdb:3CC0|rcsb pdb:4WIP|rcsb pdb:5LNP|rcsb pdb:5SUY|rcsb pdb:5SUZ|rcsb pdb:6IW3|rcsb pdb:6JCK|reactome:R-HSA-201681|reactome:R-HSA-201688|reactome:R-HSA-2028269|reactome:R-HSA-4086400|reactome:R-HSA-4608870|reactome:R-HSA-4641258|reactome:R-HSA-4641262|reactome:R-HSA-5099900|reactome:R-HSA-5368598|reactome:R-HSA-5663220|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9673324|ensembl:ENSP00000005340|dip:DIP-34433N|entrezgene/locuslink:1856(identity)	-	crc64:5915C97FA39D6AFC	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:bgMS2UPxQlkuE3+ip5+hgnIdNrE559292	rogid:2Vdc8oRnT4Mz/j+EXQXrL3AszOc9606	intact-crc:4241F48BBEF8B603|rigid:+Y9vAv49+0LSxYqVFXNA/5VMQgU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12460	uniprotkb:Q8NHQ1	intact:EBI-17148|ensemblfungi:YLR197W|uniprotkb:D6VYK0	intact:EBI-739624|ensembl:ENSP00000264982|ensembl:ENSP00000419231|uniprotkb:Q96B31|uniprotkb:Q9H2C3|uniprotkb:Q9H2Z1|uniprotkb:Q9H940|uniprotkb:D3DNE9|uniprotkb:B7Z5I8|uniprotkb:B7Z7E8|uniprotkb:F5GZX8	psi-mi:nop56_yeast(display_long)|uniprotkb:SIK1(gene name synonym)|uniprotkb:Ribosome biosynthesis protein SIK1(gene name synonym)|uniprotkb:YLR197W(locus name)|uniprotkb:L8167.9(orf name)|uniprotkb:NOP56(gene name)|psi-mi:NOP56(display_short)|uniprotkb:Suppressor of I kappa b protein 1(gene name synonym)	psi-mi:cep70_human(display_long)|uniprotkb:CEP70(gene name)|psi-mi:CEP70(display_short)|uniprotkb:BITE(gene name synonym)|uniprotkb:p10-binding protein(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11547886|imex:IM-24995-2698	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YLR197W(gene)|ensemblfungi:YLR197W_mRNA(transcript)|go:"GO:0000154"(rRNA modification)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|refseq:NP_013298.1|sgd:S000004187|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0030515"(snoRNA binding)|go:"GO:0030686"(90S preribosome)|go:"GO:0031428"(box C/D RNP complex)|go:"GO:0032040"(small-subunit processome)|interpro:IPR002687(Pre-mRNA processing ribonucleoprotein, binding region)|interpro:IPR012974(NOP5, N-terminal)|interpro:IPR012976(NOSIC)|interpro:IPR036070|interpro:IPR042239|rcsb pdb:5WLC|rcsb pdb:5WYJ|rcsb pdb:5WYK|rcsb pdb:6KE6|rcsb pdb:6LQP|rcsb pdb:6LQQ|rcsb pdb:6LQR|rcsb pdb:6LQS|rcsb pdb:6LQT|rcsb pdb:6LQU|rcsb pdb:6LQV|rcsb pdb:6ND4|rcsb pdb:6ZDT|rcsb pdb:6ZQA|rcsb pdb:6ZQB|rcsb pdb:6ZQC|rcsb pdb:6ZQD|rcsb pdb:6ZQE|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-6791226|dip:DIP-4405N|mint:Q12460|sgd:YLR197W(identity)	ensembl:ENSG00000114107(gene)|ensembl:ENST00000264982(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|interpro:IPR019734|interpro:IPR037692|mint:Q8NHQ1|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|ensembl:ENST00000484888(transcript)|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_077817.2|refseq:XP_016862764.1|refseq:NP_001275893.1|refseq:NP_001275894.1|refseq:NP_001275895.1|refseq:NP_001275896.1|refseq:NP_001307527.1|refseq:NP_001307529.1|entrezgene/locuslink:80321(identity)	-	crc64:F8522A5870EF4842	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:l3UAmoOUECH1uov6nv7MSwSv/3s559292	rogid:S4yveQWcvdVtAUX65gqrJ5Dv0Mc9606	intact-crc:F5ADF9140D4FDC06|rigid:RlecPvmCstDP0ZnBJvCs/F+2cLA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q16637-3	uniprotkb:Q12460	intact:EBI-395447|ensembl:ENSP00000424926|ensembl:ENSP00000486152|ensembl:ENSP00000487015|ensembl:ENSP00000487029|intact:EBI-8628183|intact:MINT-95595	intact:EBI-17148|ensemblfungi:YLR197W|uniprotkb:D6VYK0	psi-mi:q16637-3(display_long)|uniprotkb:Iso7-SMN(isoform synonym)|uniprotkb:SMN1(gene name)|psi-mi:SMN1(display_short)|uniprotkb:SMN2(gene name)|psi-mi:SMN2(display_short)|uniprotkb:SMN(gene name synonym)|uniprotkb:SMNT(gene name synonym)|uniprotkb:SMNC(gene name synonym)|uniprotkb:Component of gems 1(gene name synonym)|uniprotkb:Gemin-1(gene name synonym)	psi-mi:nop56_yeast(display_long)|uniprotkb:SIK1(gene name synonym)|uniprotkb:Ribosome biosynthesis protein SIK1(gene name synonym)|uniprotkb:YLR197W(locus name)|uniprotkb:L8167.9(orf name)|uniprotkb:NOP56(gene name)|psi-mi:NOP56(display_short)|uniprotkb:Suppressor of I kappa b protein 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11547877|imex:IM-24995-2697	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-395421(smn_human)|ensembl:ENSG00000275349(gene)|ensembl:ENST00000506163(transcript)|ensembl:ENST00000626847(transcript)|ensembl:ENST00000628353(transcript)|ensembl:ENST00000628642(transcript)|ensembl:ENSG00000172062(gene)|ensembl:ENSG00000205571(gene)|ensembl:ENSG00000273772(gene)|uniprotkb:Q16637-3(isoform-parent)|entrezgene/locuslink:6607(identity)	ensemblfungi:YLR197W(gene)|ensemblfungi:YLR197W_mRNA(transcript)|go:"GO:0000154"(rRNA modification)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|refseq:NP_013298.1|sgd:S000004187|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0030515"(snoRNA binding)|go:"GO:0030686"(90S preribosome)|go:"GO:0031428"(box C/D RNP complex)|go:"GO:0032040"(small-subunit processome)|interpro:IPR002687(Pre-mRNA processing ribonucleoprotein, binding region)|interpro:IPR012974(NOP5, N-terminal)|interpro:IPR012976(NOSIC)|interpro:IPR036070|interpro:IPR042239|rcsb pdb:5WLC|rcsb pdb:5WYJ|rcsb pdb:5WYK|rcsb pdb:6KE6|rcsb pdb:6LQP|rcsb pdb:6LQQ|rcsb pdb:6LQR|rcsb pdb:6LQS|rcsb pdb:6LQT|rcsb pdb:6LQU|rcsb pdb:6LQV|rcsb pdb:6ND4|rcsb pdb:6ZDT|rcsb pdb:6ZQA|rcsb pdb:6ZQB|rcsb pdb:6ZQC|rcsb pdb:6ZQD|rcsb pdb:6ZQE|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-6791226|dip:DIP-4405N|mint:Q12460|sgd:YLR197W(identity)	-	isoform-comment:Thought to be a non-functional protein that lacks the capacity to oligomerize and thus cannot interact with Sm proteins. Primarily derived from SMN2 gene.	crc64:F8522A5870EF4842	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:ICA63eidVxJ219M+YZJ20zNh+xU9606	rogid:l3UAmoOUECH1uov6nv7MSwSv/3s559292	intact-crc:1EC61DFF17538B3A|rigid:SFi50B0QqmFhNR2JwpnQnRCGfjs	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12460	uniprotkb:Q16637	intact:EBI-17148|ensemblfungi:YLR197W|uniprotkb:D6VYK0	intact:EBI-395421|uniprotkb:Q13119|uniprotkb:Q549U5|uniprotkb:Q96J51|ensembl:ENSP00000305857|uniprotkb:A8K0V4|ensembl:ENSP00000370083|ensembl:ENSP00000370117|ensembl:ENSP00000370119|ensembl:ENSP00000479920|ensembl:ENSP00000482966|ensembl:ENSP00000483515|ensembl:ENSP00000483819|ensembl:ENSP00000487206|ensembl:ENSP00000487421	psi-mi:nop56_yeast(display_long)|uniprotkb:SIK1(gene name synonym)|uniprotkb:Ribosome biosynthesis protein SIK1(gene name synonym)|uniprotkb:YLR197W(locus name)|uniprotkb:L8167.9(orf name)|uniprotkb:NOP56(gene name)|psi-mi:NOP56(display_short)|uniprotkb:Suppressor of I kappa b protein 1(gene name synonym)	psi-mi:smn_human(display_long)|uniprotkb:SMN1(gene name)|psi-mi:SMN1(display_short)|uniprotkb:SMN(gene name synonym)|uniprotkb:SMNT(gene name synonym)|uniprotkb:SMN2(gene name)|psi-mi:SMN2(display_short)|uniprotkb:SMNC(gene name synonym)|uniprotkb:Component of gems 1(gene name synonym)|uniprotkb:Gemin-1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11547868|imex:IM-24995-2696	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YLR197W(gene)|ensemblfungi:YLR197W_mRNA(transcript)|go:"GO:0000154"(rRNA modification)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|refseq:NP_013298.1|sgd:S000004187|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0030515"(snoRNA binding)|go:"GO:0030686"(90S preribosome)|go:"GO:0031428"(box C/D RNP complex)|go:"GO:0032040"(small-subunit processome)|interpro:IPR002687(Pre-mRNA processing ribonucleoprotein, binding region)|interpro:IPR012974(NOP5, N-terminal)|interpro:IPR012976(NOSIC)|interpro:IPR036070|interpro:IPR042239|rcsb pdb:5WLC|rcsb pdb:5WYJ|rcsb pdb:5WYK|rcsb pdb:6KE6|rcsb pdb:6LQP|rcsb pdb:6LQQ|rcsb pdb:6LQR|rcsb pdb:6LQS|rcsb pdb:6LQT|rcsb pdb:6LQU|rcsb pdb:6LQV|rcsb pdb:6ND4|rcsb pdb:6ZDT|rcsb pdb:6ZQA|rcsb pdb:6ZQB|rcsb pdb:6ZQC|rcsb pdb:6ZQD|rcsb pdb:6ZQE|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-6791226|dip:DIP-4405N|mint:Q12460|sgd:YLR197W(identity)	refseq:NP_000335.1|refseq:NP_059107.1|refseq:NP_075012.1|refseq:NP_075013.1|refseq:NP_075014.1|refseq:NP_075015.1|ensembl:ENSG00000172062(gene)|ensembl:ENSG00000205571(gene)|ensembl:ENSG00000273772(gene)|ensembl:ENSG00000275349(gene)|ensembl:ENSG00000277773(gene)|ensembl:ENST00000351205(transcript)|ensembl:ENST00000380707(transcript)|ensembl:ENST00000380741(transcript)|ensembl:ENST00000380743(transcript)|ensembl:ENST00000614610(transcript)|ensembl:ENST00000618251(transcript)|ensembl:ENST00000618661(transcript)|ensembl:ENST00000622739(transcript)|ensembl:ENST00000627341(transcript)|ensembl:ENST00000629122(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0007399"(nervous system development)|go:"GO:0015030"(Cajal body)|go:"GO:0016604"(nuclear body)|go:"GO:0030018"(Z disc)|go:"GO:0030424"(axon)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043204"(perikaryon)|go:"GO:0097504"(Gemini of coiled bodies)|interpro:IPR002999(Tudor)|interpro:IPR010304(Survival motor neuron)|mint:Q16637|rcsb pdb:1G5V|rcsb pdb:1MHN|rcsb pdb:2LEH|rcsb pdb:4A4E|rcsb pdb:4A4G|rcsb pdb:4GLI|rcsb pdb:4QQ6|rcsb pdb:5XJL|go:"GO:0034719"(SMN-Sm protein complex)|rcsb pdb:5XJQ|rcsb pdb:5XJR|rcsb pdb:5XJS|rcsb pdb:5XJT|rcsb pdb:5XJU|reactome:R-HSA-191859|go:"GO:0032797"(SMN complex)|refseq:NP_001284644.1|ensembl:ENSP00000305857|ensembl:ENSP00000370083|ensembl:ENSP00000370117|ensembl:ENST00000380742|ensembl:ENSP00000370118|ensembl:ENSP00000370119|ensembl:ENST00000503079|ensembl:ENSP00000428128|ensembl:ENST00000506163|ensembl:ENSP00000424926|ensembl:ENST00000611442|ensembl:ENSP00000483768|ensembl:ENST00000614240|ensembl:ENSP00000479279|ensembl:ENSP00000479920|ensembl:ENST00000614773|ensembl:ENSP00000481427|ensembl:ENSP00000483515|ensembl:ENSP00000483819|ensembl:ENST00000622158|ensembl:ENSP00000480906|ensembl:ENSP00000482966|ensembl:ENST00000624634|ensembl:ENSP00000485595|ensembl:ENST00000626847|ensembl:ENSP00000486152|ensembl:ENSP00000487421|ensembl:ENST00000628353|ensembl:ENSP00000487029|ensembl:ENST00000628642|ensembl:ENSP00000487015|ensembl:ENSP00000487206|refseq:XP_016865275.1|dip:DIP-31309N|entrezgene/locuslink:6607(identity)	-	crc64:F8522A5870EF4842	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:l3UAmoOUECH1uov6nv7MSwSv/3s559292	rogid:QGivm7E8suciCWXO4l0zCUzCl2g9606	intact-crc:4DB2FB8BB020100D|rigid:P7RgU+Kz+2UAHNUypIgPhi0aL0o	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12446	uniprotkb:Q9NYB9-2	intact:EBI-10022|uniprotkb:D6W2N7|ensemblfungi:YOR181W	intact:EBI-11096309|ensembl:ENSP00000261017	psi-mi:las17_yeast(display_long)|uniprotkb:LAS17(gene name)|psi-mi:LAS17(display_short)|uniprotkb:YOR181W(locus name)	psi-mi:q9nyb9-2(display_long)|uniprotkb:ABI2(gene name)|psi-mi:ABI2(display_short)|uniprotkb:ARGBPIA(gene name synonym)|uniprotkb:Abelson interactor 2(gene name synonym)|uniprotkb:Abl-binding protein 3(gene name synonym)|uniprotkb:Arg-binding protein 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11547859|imex:IM-24995-2695	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014824.1|sgd:S000005707|ensemblfungi:YOR181W(gene)|ensemblfungi:YOR181W_mRNA(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007015"(actin filament organization)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030479"(actin cortical patch)|go:"GO:0032233"(positive regulation of actin filament bundle assembly)|go:"GO:0043332"(mating projection tip)|go:"GO:0045010"(actin nucleation)|go:"GO:0051666"(actin cortical patch localization)|go:"GO:0071933"(Arp2/3 complex binding)|go:"GO:0140224"(SLAC complex)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR000697(EVH1)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR027641|interpro:IPR033927|rcsb pdb:1ZUK|dip:DIP-963N|mint:Q12446|sgd:YOR181W(identity)	intact:EBI-743598(isoform-parent)|ensembl:ENSG00000138443(gene)|ensembl:ENST00000261017(transcript)|uniprotkb:Q9NYB9-2(isoform-parent)|entrezgene/locuslink:10152(identity)	-	crc64:4488355563AA2645	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:TfQ256gBQPp1T8Ntu2AvktFnypA559292	rogid:VNi9aUeavD8+CCi+n1DXS+7mmbs9606	intact-crc:22A1124713FC44CC|rigid:sfFzHpyPEZSJfLqmdNn/LCsybpA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12446	uniprotkb:O43639	intact:EBI-10022|uniprotkb:D6W2N7|ensemblfungi:YOR181W	intact:EBI-713635|uniprotkb:Q9BWN9|uniprotkb:Q9UIC3|ensembl:ENSP00000233154|ensembl:ENSP00000377018|uniprotkb:D3DVK1	psi-mi:las17_yeast(display_long)|uniprotkb:LAS17(gene name)|psi-mi:LAS17(display_short)|uniprotkb:YOR181W(locus name)	psi-mi:nck2_human(display_long)|uniprotkb:NCK adaptor protein 2(gene name synonym)|uniprotkb:SH2/SH3 adaptor protein NCK-beta(gene name synonym)|uniprotkb:NCK2(gene name)|psi-mi:NCK2(display_short)|uniprotkb:GRB4(gene name synonym)|uniprotkb:Growth factor receptor-bound protein 4(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11547850|imex:IM-24995-2694	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014824.1|sgd:S000005707|ensemblfungi:YOR181W(gene)|ensemblfungi:YOR181W_mRNA(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007015"(actin filament organization)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030479"(actin cortical patch)|go:"GO:0032233"(positive regulation of actin filament bundle assembly)|go:"GO:0043332"(mating projection tip)|go:"GO:0045010"(actin nucleation)|go:"GO:0051666"(actin cortical patch localization)|go:"GO:0071933"(Arp2/3 complex binding)|go:"GO:0140224"(SLAC complex)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR000697(EVH1)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR027641|interpro:IPR033927|rcsb pdb:1ZUK|dip:DIP-963N|mint:Q12446|sgd:YOR181W(identity)	refseq:XP_006712860.1|refseq:NP_001004720.1|refseq:NP_003572.2|ensembl:ENSG00000071051(gene)|ensembl:ENST00000233154(transcript)|ensembl:ENST00000393349(transcript)|go:"GO:0001771"(immunological synapse formation)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0007015"(actin filament organization)|go:"GO:0007165"(signal transduction)|go:"GO:0007172"(signal complex assembly)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007176"(regulation of epidermal growth factor-activated receptor activity)|go:"GO:0008093"(cytoskeletal anchor activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0012506"(vesicle membrane)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016477"(cell migration)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0036493"(positive regulation of translation in response to endoplasmic reticulum stress)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042110"(T cell activation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0060996"(dendritic spine development)|go:"GO:0097110"(scaffold protein binding)|go:"GO:1902237"(positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903898"(negative regulation of PERK-mediated unfolded protein response)|go:"GO:1903912"(negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation)|go:"GO:1990441"(negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR017304(Cytoplasmic, NCK)|interpro:IPR028524|interpro:IPR035559|interpro:IPR035560|interpro:IPR035561|interpro:IPR035883|interpro:IPR036028|interpro:IPR036860|mint:O43639|rcsb pdb:1U5S|rcsb pdb:1WX6|rcsb pdb:1Z3K|rcsb pdb:2B86|rcsb pdb:2CIA|rcsb pdb:2FRW|rcsb pdb:2FRY|rcsb pdb:2JXB|rcsb pdb:4E6R|reactome:R-HSA-186763|reactome:R-HSA-373753|reactome:R-HSA-3928664|reactome:R-HSA-428540|reactome:R-HSA-4420097|reactome:R-HSA-8985801|reactome:R-HSA-9013420|reactome:R-HSA-9013424|refseq:XP_016860592.1|refseq:XP_016860593.1|refseq:XP_016860594.1|refseq:XP_011510293.1|entrezgene/locuslink:8440(identity)	-	crc64:4488355563AA2645	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:TfQ256gBQPp1T8Ntu2AvktFnypA559292	rogid:WV9nJ78Im/ga5KQlRuSN2ODzWpQ9606	intact-crc:5B0979FFC9CA38FA|rigid:RsfL2QngUqX+Q1QuSE7cTsedaZ8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12446	uniprotkb:O43586	intact:EBI-10022|uniprotkb:D6W2N7|ensemblfungi:YOR181W	intact:EBI-1050964|uniprotkb:O43585|uniprotkb:O95657|uniprotkb:B5BUK4|uniprotkb:B5BU74|ensembl:ENSP00000452746	psi-mi:las17_yeast(display_long)|uniprotkb:LAS17(gene name)|psi-mi:LAS17(display_short)|uniprotkb:YOR181W(locus name)	psi-mi:ppip1_human(display_long)|uniprotkb:CD2-binding protein 1(gene name synonym)|uniprotkb:H-PIP(gene name synonym)|uniprotkb:PSTPIP1(gene name)|psi-mi:PSTPIP1(display_short)|uniprotkb:CD2BP1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11547841|imex:IM-24995-2693	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014824.1|sgd:S000005707|ensemblfungi:YOR181W(gene)|ensemblfungi:YOR181W_mRNA(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007015"(actin filament organization)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030479"(actin cortical patch)|go:"GO:0032233"(positive regulation of actin filament bundle assembly)|go:"GO:0043332"(mating projection tip)|go:"GO:0045010"(actin nucleation)|go:"GO:0051666"(actin cortical patch localization)|go:"GO:0071933"(Arp2/3 complex binding)|go:"GO:0140224"(SLAC complex)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR000697(EVH1)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR027641|interpro:IPR033927|rcsb pdb:1ZUK|dip:DIP-963N|mint:Q12446|sgd:YOR181W(identity)	refseq:NP_003969.2|refseq:NP_001308064.1|refseq:NP_001308066.1|ensembl:ENSG00000140368(gene)|ensembl:ENST00000558012(transcript)|go:"GO:0001931"(uropod)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0006954"(inflammatory response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0032154"(cleavage furrow)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051015"(actin filament binding)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR027267|interpro:IPR030777|interpro:IPR031160|interpro:IPR036028|mint:O43586|rcsb pdb:2DIL|reactome:R-HSA-844456|reactome:R-HSA-9660826|entrezgene/locuslink:9051(identity)	-	crc64:4488355563AA2645	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:TfQ256gBQPp1T8Ntu2AvktFnypA559292	rogid:JWK4dCYdcVF6mKwe+hoOri1wwps9606	intact-crc:D451A27B2DE46E3D|rigid:xMK64f8TXbrA2jdbHT/A3Faf260	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8IYA8	uniprotkb:Q12527	intact:EBI-8638439|intact:EBI-28969497|ensembl:ENSP00000296449|ensembl:ENSP00000391788|ensembl:ENSP00000407837|uniprotkb:C9JJL0|uniprotkb:Q96LP7|intact:MINT-8162095|uniprotkb:Q05DG9	intact:EBI-31977|uniprotkb:D6W457|ensemblfungi:YPR049C	psi-mi:iho1_human(display_long)|uniprotkb:IHO1(gene name)|psi-mi:IHO1(display_short)|uniprotkb:CCDC36(gene name synonym)|uniprotkb:Cancer/testis antigen 74(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 36(gene name synonym)	psi-mi:atg11_yeast(display_long)|uniprotkb:Cytoplasm to vacuole targeting protein 9(gene name synonym)|uniprotkb:ATG11(gene name)|psi-mi:ATG11(display_short)|uniprotkb:CVT9(gene name synonym)|uniprotkb:YPR049C(locus name)|uniprotkb:YP9499.07c(orf name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11547949|imex:IM-24995-2705	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000296449|ensembl:ENST00000366429|ensembl:ENSP00000403700|ensembl:ENSP00000391788|ensembl:ENSP00000407837|ensembl:ENSG00000173421(gene)|ensembl:ENST00000296449(transcript)|ensembl:ENST00000438782(transcript)|ensembl:ENST00000452691(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0006310"(DNA recombination)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0042138"(meiotic DNA double-strand break formation)|go:"GO:0048477"(oogenesis)|go:"GO:0060629"(regulation of homologous chromosome segregation)|interpro:IPR031529|mint:Q8IYA8|refseq:XP_011531974.1|refseq:XP_011531975.1|refseq:NP_001128669.1|refseq:NP_835467.2|refseq:XP_006713187.1|entrezgene/locuslink:339834(identity)	refseq:NP_015374.1|sgd:S000006253|dip:DIP-1492N|mint:Q12527|ensemblfungi:YPR049C(gene)|ensemblfungi:YPR049C_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000149"(SNARE binding)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0006914"(autophagy)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0034629"|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061709"(reticulophagy)|go:"GO:0140255"(regulation of cellular response to phosphate starvation)|go:"GO:1990316"(Atg1/ULK1 kinase complex)|go:"GO:2000786"(positive regulation of autophagosome assembly)|interpro:IPR019460|interpro:IPR040040|rcsb pdb:6VZF|reactome:R-SCE-1632852|sgd:YPR049C(identity)	-	comment:mint	crc64:A904B92E9AE79449	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:+TNQLExkhmC1NWqsE240Cx7zFVU9606	rogid:26PElwvrl3YKwoQU7YdkmR0ln3o559292	intact-crc:2C63F89ACD71BE8F|rigid:yVhxABq4IWXZfrlw9ybCozncEO0	false	sufficient binding region:11-594	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O43597	uniprotkb:Q12527	intact:EBI-742487|uniprotkb:Q5T6Z7|ensembl:ENSP00000366306|ensembl:ENSP00000366308|uniprotkb:B2R9J9	intact:EBI-31977|uniprotkb:D6W457|ensemblfungi:YPR049C	psi-mi:spy2_human(display_long)|uniprotkb:SPRY2(gene name)|psi-mi:SPRY2(display_short)	psi-mi:atg11_yeast(display_long)|uniprotkb:Cytoplasm to vacuole targeting protein 9(gene name synonym)|uniprotkb:ATG11(gene name)|psi-mi:ATG11(display_short)|uniprotkb:CVT9(gene name synonym)|uniprotkb:YPR049C(locus name)|uniprotkb:YP9499.07c(orf name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11547940|imex:IM-24995-2704	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005833.1|rcsb pdb:5HL0|reactome:R-HSA-1295596|reactome:R-HSA-182971|rcsb pdb:5HKZ|ensembl:ENST00000377102(transcript)|ensembl:ENST00000377104(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|ensembl:ENSG00000136158(gene)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030291"(protein serine/threonine kinase inhibitor activity)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031345"(negative regulation of cell projection organization)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0032587"(ruffle membrane)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0045165"(cell fate commitment)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048513"(animal organ development)|go:"GO:0051387"(negative regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060437"(lung growth)|go:"GO:0060449"(bud elongation involved in lung branching)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:1900747"(negative regulation of vascular endothelial growth factor signaling pathway)|go:"GO:1902747"(negative regulation of lens fiber cell differentiation)|go:"GO:1990752"(microtubule end)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR007875(Sprouty)|interpro:IPR030780|mint:O43597|rcsb pdb:3BUM|rcsb pdb:3OB1|rcsb pdb:5HKY|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|refseq:NP_001305465.1|refseq:NP_001305466.1|refseq:NP_001305467.1|entrezgene/locuslink:10253(identity)	refseq:NP_015374.1|sgd:S000006253|dip:DIP-1492N|mint:Q12527|ensemblfungi:YPR049C(gene)|ensemblfungi:YPR049C_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000149"(SNARE binding)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0006914"(autophagy)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0034629"|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061709"(reticulophagy)|go:"GO:0140255"(regulation of cellular response to phosphate starvation)|go:"GO:1990316"(Atg1/ULK1 kinase complex)|go:"GO:2000786"(positive regulation of autophagosome assembly)|interpro:IPR019460|interpro:IPR040040|rcsb pdb:6VZF|reactome:R-SCE-1632852|sgd:YPR049C(identity)	-	-	crc64:A904B92E9AE79449	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:u1omauzisc6MdZlogMotUmtauSI9606	rogid:26PElwvrl3YKwoQU7YdkmR0ln3o559292	intact-crc:6AA534045E54CA72|rigid:a/f0lR/A9heQ5jUrRycNpH6q0PA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8N9N5-2	uniprotkb:Q12511	intact:EBI-11524452|ensembl:ENSP00000347125	intact:EBI-36488|uniprotkb:D6W2F1|ensemblfungi:YOR090C	psi-mi:q8n9n5-2(display_long)|uniprotkb:BANP(gene name)|psi-mi:BANP(display_short)|uniprotkb:BEN domain-containing protein 1(gene name synonym)|uniprotkb:BEND1(gene name synonym)|uniprotkb:Btg3-associated nuclear protein(gene name synonym)|uniprotkb:SMAR1(gene name synonym)|uniprotkb:Scaffold/matrix-associated region-1-binding protein(gene name synonym)	psi-mi:pdp1_yeast(display_long)|uniprotkb:PTC5(gene name)|psi-mi:PTC5(display_short)|uniprotkb:Phosphatase two C protein 5(gene name synonym)|uniprotkb:PPP1(gene name synonym)|uniprotkb:Protein phosphatase 2C homolog 5(gene name synonym)|uniprotkb:Protein phosphatase of PDH protein 1(gene name synonym)|uniprotkb:Pyruvate dehydrogenase complex phosphatase 1(gene name synonym)|uniprotkb:YOR3157C(orf name)|uniprotkb:YOR090C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11547931|imex:IM-24995-2703	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000172530(gene)|ensembl:ENST00000355022(transcript)|intact:EBI-744695(isoform-parent)|uniprotkb:Q8N9N5-2(isoform-parent)|entrezgene/locuslink:54971(identity)	refseq:NP_014733.1|sgd:S000005616|mint:Q12511|dip:DIP-6439N|ensemblfungi:YOR090C(gene)|ensemblfungi:YOR090C_mRNA(transcript)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0004741"("[pyruvate dehydrogenase (lipoamide)] phosphatase activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:1904184"(positive regulation of pyruvate dehydrogenase activity)|interpro:IPR000222(Protein phosphatase 2C,  manganese/magnesium aspartate binding site)|interpro:IPR001932(Protein phosphatase 2C-related)|interpro:IPR015655(Protein phosphatase 2C)|interpro:IPR036457|sgd:YOR090C(identity)	-	-	crc64:07A5AF33FA72CC2A	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:ESe6iCAhvq+i57fQHz3rGyg6UOo9606	rogid:AepMamITZgBeuBC3Gni6DMkg35E559292	intact-crc:E3AC254FA0C9D28E|rigid:LbM1zrUYsHvGH+eLkyJtoDtaJ8E	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12484	uniprotkb:Q93062-3	intact:EBI-29987|uniprotkb:A0A1S0T0C0|ensemblfungi:YOR343C	intact:EBI-740343|ensembl:ENSP00000340176	psi-mi:yo343_yeast(display_long)|uniprotkb:O6287(orf name)|uniprotkb:YOR343C(locus name)	psi-mi:q93062-3(display_long)|uniprotkb:RBPMS(gene name)|psi-mi:RBPMS(display_short)|uniprotkb:HERMES(gene name synonym)|uniprotkb:Heart and RRM expressed sequence(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11547922|imex:IM-24995-2702	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005870|ensemblfungi:YOR343C(gene)|ensemblfungi:YOR343C_mRNA(transcript)|sgd:YOR343C(identity)	intact:EBI-740322(rbpms_human)|uniprotkb:Q93062-3(isoform-parent)|ensembl:ENSG00000157110(gene)|ensembl:ENST00000339877(transcript)|entrezgene/locuslink:11030(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:ULgWWTa6oS2393jSgXiCDeyIVlo559292	rogid:nlPMQAJoKEbPYBwsL3xodmCKd7c9606	intact-crc:3ACE63FAF4D4BD77|rigid:dP4sHialG+KA7qhUhJS0Z/89y2s	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O14641	uniprotkb:Q12481	intact:EBI-740850|ensembl:ENSP00000005340|uniprotkb:Q53XM0|uniprotkb:D3DTN3	intact:EBI-31770|uniprotkb:D6W2Y5|ensemblfungi:YOR287C	psi-mi:dvl2_human(display_long)|uniprotkb:DSH homolog 2(gene name synonym)|uniprotkb:DVL2(gene name)|psi-mi:DVL2(display_short)	psi-mi:rrp36_yeast(display_long)|uniprotkb:RRP36(gene name)|psi-mi:RRP36(display_short)|uniprotkb:Ribosomal RNA-processing protein 36(gene name synonym)|uniprotkb:YOR287C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11547913|imex:IM-24995-2701	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004413.1|ensembl:ENSG00000004975(gene)|ensembl:ENST00000005340(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005109"(frizzled binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0007507"(heart development)|go:"GO:0016235"(aggresome)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044340"(canonical Wnt signaling pathway involved in regulation of cell proliferation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0150012"(positive regulation of neuron projection arborization)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008341(Dishevelled-2 region)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:O14641|rcsb pdb:2REY|rcsb pdb:3CBX|rcsb pdb:3CBY|rcsb pdb:3CBZ|rcsb pdb:3CC0|rcsb pdb:4WIP|rcsb pdb:5LNP|rcsb pdb:5SUY|rcsb pdb:5SUZ|rcsb pdb:6IW3|rcsb pdb:6JCK|reactome:R-HSA-201681|reactome:R-HSA-201688|reactome:R-HSA-2028269|reactome:R-HSA-4086400|reactome:R-HSA-4608870|reactome:R-HSA-4641258|reactome:R-HSA-4641262|reactome:R-HSA-5099900|reactome:R-HSA-5368598|reactome:R-HSA-5663220|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9673324|ensembl:ENSP00000005340|dip:DIP-34433N|entrezgene/locuslink:1856(identity)	refseq:NP_014930.1|sgd:S000005813|interpro:IPR009292(Protein of unknown function DUF947)|mint:Q12481|ensemblfungi:YOR287C(gene)|ensemblfungi:YOR287C_mRNA(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000469"(cleavage involved in rRNA processing)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0030686"(90S preribosome)|go:"GO:0042274"(ribosomal small subunit biogenesis)|reactome:R-SCE-6791226|sgd:YOR287C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:2Vdc8oRnT4Mz/j+EXQXrL3AszOc9606	rogid:q1HXpxSZvQpnhGzVXmnBNEfWTzI559292	intact-crc:12AE807E8AE0675E|rigid:urwWPQOYg+0Za6KFpv7PEA0rWqo	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12476	uniprotkb:Q9BRK4	intact:EBI-31475|uniprotkb:D6VRH7|ensemblfungi:YDL175C	intact:EBI-741037|ensembl:ENSP00000359240|ensembl:ENSP00000359243|uniprotkb:Q8N3I0|uniprotkb:Q96J79|uniprotkb:Q96JL2|uniprotkb:B1AL14|uniprotkb:D3DR72	psi-mi:air2_yeast(display_long)|uniprotkb:Arginine methyltransferase-interacting RING finger protein 2(gene name synonym)|uniprotkb:AIR2(gene name)|psi-mi:AIR2(display_short)|uniprotkb:YDL175C(locus name)	psi-mi:lzts2_human(display_long)|uniprotkb:Protein LAPSER1(gene name synonym)|uniprotkb:LZTS2(gene name)|psi-mi:LZTS2(display_short)|uniprotkb:KIAA1813(gene name synonym)|uniprotkb:LAPSER1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11547904|imex:IM-24995-2700	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010106.1|sgd:S000002334|dip:DIP-2543N|mint:Q12476|ensemblfungi:YDL175C(gene)|ensemblfungi:YDL175C_mRNA(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0006400"(tRNA modification)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031499"(TRAMP complex)|go:"GO:0043629"(ncRNA polyadenylation)|go:"GO:0071031"(nuclear mRNA surveillance of mRNA 3'-end processing)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071036"(nuclear polyadenylation-dependent snoRNA catabolic process)|go:"GO:0071037"(nuclear polyadenylation-dependent snRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071039"(nuclear polyadenylation-dependent CUT catabolic process)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR016713("Poly(A) polymerase complex, Air1/2")|interpro:IPR036875|rcsb pdb:2LLI|rcsb pdb:3NYB|rcsb pdb:4U4C|sgd:YDL175C(identity)	refseq:NP_115805.1|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030496"(midbody)|go:"GO:0031982"(vesicle)|go:"GO:0051013"(microtubule severing)|go:"GO:0051168"(nuclear export)|go:"GO:0051255"(spindle midzone assembly)|go:"GO:0060682"(primary ureteric bud growth)|go:"GO:0072197"(ureter morphogenesis)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|interpro:IPR028597|mint:Q9BRK4|ensembl:ENSG00000107816(gene)|ensembl:ENST00000370220(transcript)|ensembl:ENST00000370223(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0008285"(negative regulation of cell population proliferation)|refseq:XP_016872269.1|refseq:NP_001305028.1|refseq:NP_001305029.1|refseq:NP_001305030.1|refseq:XP_005270279.1|entrezgene/locuslink:84445(identity)	-	crc64:5915C97FA39D6AFC	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:bgMS2UPxQlkuE3+ip5+hgnIdNrE559292	rogid:OaMJmnmfm6JniKUJeyg7fS6zRcw9606	intact-crc:FA72371B3ACAA9DD|rigid:csCOY3mXj3Y8GtsSvIi66tvohpw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O43765	uniprotkb:Q3E7B2	intact:EBI-347996|ensembl:ENSP00000221566|ensembl:ENSP00000503397|ensembl:ENSP00000504495|uniprotkb:Q9BTZ9|intact:EBI-1045243|uniprotkb:Q6FIA9|uniprotkb:D6W610	intact:EBI-3680840|uniprotkb:D6VWB9|ensemblfungi:YJL062W-A	psi-mi:sgta_human(display_long)|uniprotkb:SGTA(gene name)|psi-mi:SGTA(display_short)|uniprotkb:SGT(gene name synonym)|uniprotkb:Alpha-SGT(gene name synonym)|uniprotkb:Vpu-binding protein(gene name synonym)|uniprotkb:SGT1(gene name synonym)	psi-mi:coa3_yeast(display_long)|uniprotkb:COA3(gene name)|psi-mi:COA3(display_short)|uniprotkb:COX25(gene name synonym)|uniprotkb:RRG10(gene name synonym)|uniprotkb:Required for respiratory growth protein 10(gene name synonym)|uniprotkb:YJL062W-A(locus name)|uniprotkb:Cytochrome c oxidase protein 25(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11548009|imex:IM-24995-2711	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:4CPG|rcsb pdb:4GOD|rcsb pdb:4GOE|rcsb pdb:4GOF|reactome:R-HSA-9609523|rcsb pdb:2VYI|ensembl:ENSG00000104969(gene)|ensembl:ENST00000221566(transcript)|ensembl:ENST00000676943(transcript)|ensembl:ENST00000677149(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072380"(TRC complex)|go:"GO:0098850"(extrinsic component of synaptic vesicle membrane)|go:"GO:1903070"(negative regulation of ER-associated ubiquitin-dependent protein catabolic process)|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)|go:"GO:1903646"(positive regulation of chaperone-mediated protein folding)|go:"GO:1904288"(BAT3 complex binding)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR032374|mint:O43765|refseq:XP_011526480.1|refseq:NP_003012.1|entrezgene/locuslink:6449(identity)	mint:Q3E7B2|sgd:S000007611|refseq:NP_076894.3|ensemblfungi:YJL062W-A(gene)|ensemblfungi:YJL062W-A_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0031305"(integral component of mitochondrial inner membrane)|go:"GO:0033617"(mitochondrial cytochrome c oxidase assembly)|go:"GO:0070130"(negative regulation of mitochondrial translation)|interpro:IPR041752|sgd:YJL062W-A(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:r/Cyj4UJk/cS8QdrbjhTZMPCigI9606	rogid:uBAPwV/LO79+3saLLV4gAWUQPnA559292	intact-crc:A09DAE514BBDAEA6|rigid:WHn9ozY9bPYuvwX4RxDe23MdmC4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q13490	uniprotkb:Q3E793	intact:EBI-514538|uniprotkb:Q16516|uniprotkb:Q4TTG0|uniprotkb:B4E026|ensembl:ENSP00000227758|ensembl:ENSP00000477613	intact:EBI-2344281|uniprotkb:D6VPH1|ensemblfungi:YAL044W-A	psi-mi:birc2_human(display_long)|uniprotkb:Inhibitor of apoptosis protein 2(gene name synonym)|uniprotkb:TNFR2-TRAF-signaling complex protein 2(gene name synonym)|uniprotkb:IAP homolog B(gene name synonym)|uniprotkb:RING finger protein 48(gene name synonym)|uniprotkb:BIRC2(gene name)|psi-mi:BIRC2(display_short)|uniprotkb:API1(gene name synonym)|uniprotkb:MIHB(gene name synonym)|uniprotkb:RNF48(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase BIRC2(gene name synonym)|uniprotkb:Cellular inhibitor of apoptosis 1(gene name synonym)	psi-mi:bol1_yeast(display_long)|uniprotkb:BOL1(gene name)|psi-mi:BOL1(display_short)|uniprotkb:YAL044W-A(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11548000|imex:IM-24995-2710	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001157.1|refseq:NP_001243095.1|refseq:NP_001243092.1|dip:DIP-33485N|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0045471"(response to ethanol)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051087"(chaperone binding)|go:"GO:0051591"(response to cAMP)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060544"(regulation of necroptotic process)|go:"GO:0060546"(negative regulation of necroptotic process)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070266"(necroptotic process)|go:"GO:0070424"(regulation of nucleotide-binding oligomerization domain containing signaling pathway)|go:"GO:0098770"(FBXO family protein binding)|go:"GO:1901222"(regulation of NIK/NF-kappaB signaling)|go:"GO:1902443"(negative regulation of ripoptosome assembly involved in necroptotic process)|go:"GO:1902523"(positive regulation of protein K63-linked ubiquitination)|go:"GO:1902524"(positive regulation of protein K48-linked ubiquitination)|go:"GO:1902527"(positive regulation of protein monoubiquitination)|go:"GO:2000116"(regulation of cysteine-type endopeptidase activity)|go:"GO:2000377"(regulation of reactive oxygen species metabolic process)|interpro:IPR001315(Caspase Recruitment)|interpro:IPR001370(Proteinase inhibitor I32, inhibitor of apoptosis)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011029(DEATH-like)|interpro:IPR041933|mint:Q13490|rcsb pdb:1QBH|rcsb pdb:2L9M|rcsb pdb:3D9T|rcsb pdb:3D9U|rcsb pdb:3M1D|rcsb pdb:3MUP|rcsb pdb:3OZ1|rcsb pdb:3T6P|rcsb pdb:3UW4|rcsb pdb:4EB9|rcsb pdb:4HY4|rcsb pdb:4HY5|rcsb pdb:4KMN|rcsb pdb:4LGE|rcsb pdb:4LGU|rcsb pdb:4MTI|rcsb pdb:4MU7|rcsb pdb:5M6N|rcsb pdb:6EXW|rcsb pdb:6HPR|rcsb pdb:6W74|rcsb pdb:6W7O|rcsb pdb:6W8I|reactome:R-HSA-111465|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-5213460|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5668541|reactome:R-HSA-5675482|reactome:R-HSA-5676594|reactome:R-HSA-5689880|reactome:R-HSA-937041|ensembl:ENSG00000110330(gene)|ensembl:ENST00000227758(transcript)|ensembl:ENST00000613397(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001741"(XY body)|go:"GO:0001890"(placenta development)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0016740"(transferase activity)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034121"(regulation of toll-like receptor signaling pathway)|go:"GO:0035631"(CD40 receptor complex)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0039535"(regulation of RIG-I signaling pathway)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|entrezgene/locuslink:329(identity)	refseq:NP_075206.1|sgd:S000007586|interpro:IPR002634(BolA-like protein)|interpro:IPR036065|ensemblfungi:YAL044W-A(gene)|ensemblfungi:YAL044W-A_mRNA(transcript)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0044572"([4Fe-4S] cluster assembly)|go:"GO:0106035"(protein maturation by [4Fe-4S] cluster transfer)|sgd:YAL044W-A(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:FOikzyDyDtlv2l69i/WNDNq674A9606	rogid:9pYGPvGIU56X3neAXP8LQXxWfC4559292	intact-crc:D36B28F784158239|rigid:axSefRuPDtrVgBhaqjmLlfAFKg8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P98170	uniprotkb:Q3E793	intact:EBI-517127|uniprotkb:Q9NQ14|uniprotkb:D3DTF2|ensembl:ENSP00000347858|ensembl:ENSP00000360242|ensembl:ENSP00000395230	intact:EBI-2344281|uniprotkb:D6VPH1|ensemblfungi:YAL044W-A	psi-mi:xiap_human(display_long)|uniprotkb:Inhibitor of apoptosis protein 3(gene name synonym)|uniprotkb:X-linked inhibitor of apoptosis protein(gene name synonym)|uniprotkb:IAP-like protein(gene name synonym)|uniprotkb:XIAP(gene name)|psi-mi:XIAP(display_short)|uniprotkb:API3(gene name synonym)|uniprotkb:IAP3(gene name synonym)|uniprotkb:BIRC4(gene name synonym)|uniprotkb:Baculoviral IAP repeat-containing protein 4(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase XIAP(gene name synonym)	psi-mi:bol1_yeast(display_long)|uniprotkb:BOL1(gene name)|psi-mi:BOL1(display_short)|uniprotkb:YAL044W-A(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11547991|imex:IM-24995-2709	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006724817.1|refseq:NP_001158.2|refseq:NP_001191330.1|refseq:XP_011529631.1|dip:DIP-27626N|ensembl:ENSG00000101966(gene)|ensembl:ENST00000355640(transcript)|ensembl:ENST00000371199(transcript)|ensembl:ENST00000434753(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005876"(spindle microtubule)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030510"(regulation of BMP signaling pathway)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0055070"(copper ion homeostasis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070424"(regulation of nucleotide-binding oligomerization domain containing signaling pathway)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:1902530"(positive regulation of protein linear polyubiquitination)|go:"GO:1990001"(inhibition of cysteine-type endopeptidase activity involved in apoptotic process)|interpro:IPR001370(Proteinase inhibitor I32, inhibitor of apoptosis)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011029(DEATH-like)|interpro:IPR042579|mint:P98170|rcsb pdb:1C9Q|rcsb pdb:1F9X|rcsb pdb:1G3F|rcsb pdb:1G73|rcsb pdb:1I3O|rcsb pdb:1I4O|rcsb pdb:1I51|rcsb pdb:1KMC|rcsb pdb:1NW9|rcsb pdb:1TFQ|rcsb pdb:1TFT|rcsb pdb:2ECG|rcsb pdb:2JK7|rcsb pdb:2KNA|rcsb pdb:2OPY|rcsb pdb:2OPZ|rcsb pdb:2POI|rcsb pdb:2POP|rcsb pdb:2QRA|rcsb pdb:2VSL|rcsb pdb:3CLX|rcsb pdb:3CM2|rcsb pdb:3CM7|rcsb pdb:3EYL|rcsb pdb:3G76|rcsb pdb:3HL5|rcsb pdb:3UW4|rcsb pdb:3UW5|rcsb pdb:4EC4|rcsb pdb:4HY0|rcsb pdb:4IC2|rcsb pdb:4IC3|rcsb pdb:4J3Y|rcsb pdb:4J44|rcsb pdb:4J45|rcsb pdb:4J46|rcsb pdb:4J47|rcsb pdb:4J48|rcsb pdb:4KJU|rcsb pdb:4KJV|rcsb pdb:4KMP|rcsb pdb:4MTZ|rcsb pdb:4OXC|rcsb pdb:4WVS|rcsb pdb:4WVT|rcsb pdb:4WVU|rcsb pdb:5C0K|rcsb pdb:5C0L|rcsb pdb:5C3H|rcsb pdb:5C3K|rcsb pdb:5C7A|rcsb pdb:5C7B|rcsb pdb:5C7C|rcsb pdb:5C7D|rcsb pdb:5C83|rcsb pdb:5C84|rcsb pdb:5M6E|rcsb pdb:5M6F|rcsb pdb:5M6H|rcsb pdb:5M6L|rcsb pdb:5M6M|rcsb pdb:5O6T|rcsb pdb:5OQW|rcsb pdb:6EY2|rcsb pdb:6GJW|rcsb pdb:6QCI|reactome:R-HSA-111459|reactome:R-HSA-111463|reactome:R-HSA-111464|reactome:R-HSA-111469|reactome:R-HSA-3769402|reactome:R-HSA-5213460|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5675482|reactome:R-HSA-8948747|reactome:R-HSA-8948751|reactome:R-HSA-9627069|entrezgene/locuslink:331(identity)	refseq:NP_075206.1|sgd:S000007586|interpro:IPR002634(BolA-like protein)|interpro:IPR036065|ensemblfungi:YAL044W-A(gene)|ensemblfungi:YAL044W-A_mRNA(transcript)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0044572"([4Fe-4S] cluster assembly)|go:"GO:0106035"(protein maturation by [4Fe-4S] cluster transfer)|sgd:YAL044W-A(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:6eDcOay+c2ZmIAD/pwnCDROBwgM9606	rogid:9pYGPvGIU56X3neAXP8LQXxWfC4559292	intact-crc:8706E0C630BCC138|rigid:53Mz0OG+9oFHUkS4vej15mgo2lo	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O76003	uniprotkb:Q3E793	intact:EBI-374781|uniprotkb:Q96CE0|uniprotkb:Q9P1B0|uniprotkb:Q9P1B1|uniprotkb:B3KMP7|uniprotkb:B3KMQ5|uniprotkb:Q5JV01|ensembl:ENSP00000330836|ensembl:ENSP00000357633|ensembl:ENSP00000435445|uniprotkb:D3DRG2	intact:EBI-2344281|uniprotkb:D6VPH1|ensemblfungi:YAL044W-A	psi-mi:glrx3_human(display_long)|uniprotkb:GLRX3(gene name)|psi-mi:GLRX3(display_short)|uniprotkb:Thioredoxin-like protein 2(gene name synonym)|uniprotkb:PKC-interacting cousin of thioredoxin(gene name synonym)|uniprotkb:PKC-theta-interacting protein(gene name synonym)|uniprotkb:PICOT(gene name synonym)|uniprotkb:HUSSY-22(orf name)|uniprotkb:TXNL2(gene name synonym)	psi-mi:bol1_yeast(display_long)|uniprotkb:BOL1(gene name)|psi-mi:BOL1(display_short)|uniprotkb:YAL044W-A(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11547979|imex:IM-24995-2708	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000108010(gene)|ensembl:ENST00000331244(transcript)|ensembl:ENST00000368644(transcript)|ensembl:ENST00000481034(transcript)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0003723"(RNA binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0030018"(Z disc)|go:"GO:0030425"(dendrite)|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051536"(iron-sulfur cluster binding)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|go:"GO:0097573"(glutathione oxidoreductase activity)|interpro:IPR002109(Glutaredoxin)|interpro:IPR004480(Glutaredoxin-related protein)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR033658|interpro:IPR036249|mint:O76003|rcsb pdb:2DIY|rcsb pdb:2WZ9|rcsb pdb:2YAN|rcsb pdb:3ZYW|reactome:R-HSA-917937|refseq:NP_001186797.1|refseq:NP_006532.2|dip:DIP-31306N|entrezgene/locuslink:10539(identity)	refseq:NP_075206.1|sgd:S000007586|interpro:IPR002634(BolA-like protein)|interpro:IPR036065|ensemblfungi:YAL044W-A(gene)|ensemblfungi:YAL044W-A_mRNA(transcript)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0044572"([4Fe-4S] cluster assembly)|go:"GO:0106035"(protein maturation by [4Fe-4S] cluster transfer)|sgd:YAL044W-A(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:iKUSt6zbNzzXSKvW+vXMq3hKsEM9606	rogid:9pYGPvGIU56X3neAXP8LQXxWfC4559292	intact-crc:E5B1C9A9C9456B69|rigid:97YEt2Aehe3ybPhcvT6guyxTdD4	false	sufficient binding region:147-335	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96BA8	uniprotkb:Q12746	intact:EBI-6942903|ensembl:ENSP00000481956|intact:MINT-268046|intact:MINT-8162577|uniprotkb:Q8N2D5|uniprotkb:Q96CP0	intact:EBI-27973|uniprotkb:D6W0G0|ensemblfungi:YML125C	psi-mi:cr3l1_human(display_long)|uniprotkb:CREB3L1(gene name)|psi-mi:CREB3L1(display_short)|uniprotkb:OASIS(gene name synonym)|uniprotkb:PSEC0238(orf name)|uniprotkb:Old astrocyte specifically-induced substance(gene name synonym)	psi-mi:pga3_yeast(display_long)|uniprotkb:YML125C(locus name)|uniprotkb:YM4987.10C(orf name)|uniprotkb:YM7056.01C(orf name)|uniprotkb:PGA3(gene name)|psi-mi:PGA3(display_short)|uniprotkb:NQR1(gene name synonym)|uniprotkb:Processing of GAS1 and ALP protein 3(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11547969|imex:IM-24995-2707	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157613(gene)|ensembl:ENST00000621158(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0070278"(extracellular matrix constituent secretion)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029805|mint:Q96BA8|reactome:R-HSA-8874211|refseq:NP_443086.1|entrezgene/locuslink:90993(identity)	refseq:NP_013581.1|sgd:S000004594|dip:DIP-4519N|ensemblfungi:YML125C(gene)|ensemblfungi:YML125C_mRNA(transcript)|go:"GO:0004128"("cytochrome-b5 reductase activity, acting on NAD(P)H")|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|interpro:IPR001433("Oxidoreductase FAD/NAD(P)-binding")|interpro:IPR001709(Flavoprotein pyridine nucleotide cytochrome reductase)|interpro:IPR001834("NADH:cytochrome b5 reductase (CBR)")|interpro:IPR008333(Oxidoreductase FAD-binding region)|interpro:IPR017927|interpro:IPR017938|interpro:IPR039261|sgd:YML125C(identity)	-	comment:mint|function:"Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE"	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:sMWUFmBeBBCO+T0Y2CuB/un1lBg9606	rogid:+YTQtKGq+TXHYomne3IHzSiugt4559292	intact-crc:2185D34FC137823E|rigid:s6UzOJF+NDIejfkL7xf1IporXzc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12746	uniprotkb:Q8N6L0	intact:EBI-27973|uniprotkb:D6W0G0|ensemblfungi:YML125C	intact:EBI-749265|uniprotkb:Q96MC3|ensembl:ENSP00000404220	psi-mi:pga3_yeast(display_long)|uniprotkb:YML125C(locus name)|uniprotkb:YM4987.10C(orf name)|uniprotkb:YM7056.01C(orf name)|uniprotkb:PGA3(gene name)|psi-mi:PGA3(display_short)|uniprotkb:NQR1(gene name synonym)|uniprotkb:Processing of GAS1 and ALP protein 3(gene name synonym)	psi-mi:kash5_human(display_long)|uniprotkb:KASH5(gene name)|psi-mi:KASH5(display_short)|uniprotkb:CCDC155(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 155(gene name synonym)|uniprotkb:KASH domain-containing protein 5(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11547960|imex:IM-24995-2706	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013581.1|sgd:S000004594|dip:DIP-4519N|ensemblfungi:YML125C(gene)|ensemblfungi:YML125C_mRNA(transcript)|go:"GO:0004128"("cytochrome-b5 reductase activity, acting on NAD(P)H")|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|interpro:IPR001433("Oxidoreductase FAD/NAD(P)-binding")|interpro:IPR001709(Flavoprotein pyridine nucleotide cytochrome reductase)|interpro:IPR001834("NADH:cytochrome b5 reductase (CBR)")|interpro:IPR008333(Oxidoreductase FAD-binding region)|interpro:IPR017927|interpro:IPR017938|interpro:IPR039261|sgd:YML125C(identity)	refseq:NP_653289.3|ensembl:ENSG00000161609(gene)|ensembl:ENST00000447857(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034397"(telomere localization)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051225"(spindle assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0090172"(microtubule cytoskeleton organization involved in homologous chromosome segregation)|go:"GO:0090220"(chromosome localization to nuclear envelope involved in homologous chromosome segregation)|go:"GO:0090619"(meiotic spindle pole)|interpro:IPR011992(EF-Hand type)|interpro:IPR028168|interpro:IPR028170|interpro:IPR039508|mint:Q8N6L0|rcsb pdb:6R2I|rcsb pdb:6WMF|entrezgene/locuslink:147872(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:+YTQtKGq+TXHYomne3IHzSiugt4559292	rogid:Wl9L7AcvDHCZuKjYLn8QgGIbZTc9606	intact-crc:9FA7D8477A3F0CD0|rigid:ATjn9y8MMQnYHvcrAnCXMwya3cI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8N9N5-2	uniprotkb:Q8TGM2	intact:EBI-11524452|ensembl:ENSP00000347125	intact:EBI-11537624|ensemblfungi:YLR347W-A	psi-mi:q8n9n5-2(display_long)|uniprotkb:BANP(gene name)|psi-mi:BANP(display_short)|uniprotkb:BEN domain-containing protein 1(gene name synonym)|uniprotkb:BEND1(gene name synonym)|uniprotkb:Btg3-associated nuclear protein(gene name synonym)|uniprotkb:SMAR1(gene name synonym)|uniprotkb:Scaffold/matrix-associated region-1-binding protein(gene name synonym)	psi-mi:yl347_yeast(display_long)|uniprotkb:YLR347W-A(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11548066|imex:IM-24995-2717	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000172530(gene)|ensembl:ENST00000355022(transcript)|intact:EBI-744695(isoform-parent)|uniprotkb:Q8N9N5-2(isoform-parent)|entrezgene/locuslink:54971(identity)	sgd:S000028681|ensemblfungi:YLR347W-A(gene)|ensemblfungi:YLR347W-A_mRNA(transcript)|sgd:YLR347W-A(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/03/16	rogid:ESe6iCAhvq+i57fQHz3rGyg6UOo9606	rogid:eZ3330guTyvylD3kiCyArvlGWGI559292	intact-crc:A3E18DE97993F84A|rigid:I04O0BHD1/XyGh9QCQ1E7JgUl5o	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8TGM2	uniprotkb:Q15654	intact:EBI-11537624|ensemblfungi:YLR347W-A	intact:EBI-742327|uniprotkb:O15170|uniprotkb:O15275|uniprotkb:Q9BTB2|uniprotkb:Q9BUE5|uniprotkb:Q9BXP3|uniprotkb:Q9UNT4|uniprotkb:A4D2E7|ensembl:ENSP00000200457|uniprotkb:F2ZC07|uniprotkb:F2ZC08	psi-mi:yl347_yeast(display_long)|uniprotkb:YLR347W-A(locus name)	psi-mi:trip6_human(display_long)|uniprotkb:TRIP6(gene name)|psi-mi:TRIP6(display_short)|uniprotkb:OIP1(gene name synonym)|uniprotkb:Opa-interacting protein 1(gene name synonym)|uniprotkb:Zyxin-related protein 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11548056|imex:IM-24995-2716	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000028681|ensemblfungi:YLR347W-A(gene)|ensemblfungi:YLR347W-A_mRNA(transcript)|sgd:YLR347W-A(identity)	refseq:NP_003293.2|ensembl:ENSP00000200457|ensembl:ENST00000417475|ensembl:ENSP00000413817|ensembl:ENST00000437505|ensembl:ENSP00000410736|ensembl:ENST00000619988|ensembl:ENSP00000479865|ensembl:ENSG00000087077(gene)|ensembl:ENST00000200457(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003723"(RNA binding)|go:"GO:0005149"(interleukin-1 receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0019900"(kinase binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0043009"(chordate embryonic development)|go:"GO:0046872"(metal ion binding)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|interpro:IPR001781(Zinc finger, LIM-type)|mint:Q15654|rcsb pdb:1X61|rcsb pdb:2DLO|dip:DIP-34466N|entrezgene/locuslink:7205(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/03/16	rogid:eZ3330guTyvylD3kiCyArvlGWGI559292	rogid:9Okf3b6sMMwX5awAx991GN9iSsQ9606	intact-crc:F6F4C902D06D0109|rigid:j9x6kqXpb1RT8oOpj+apAitcB6I	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8TGM2	intact:EBI-11524292	intact:EBI-11537624|ensemblfungi:YLR347W-A	-	psi-mi:yl347_yeast(display_long)|uniprotkb:YLR347W-A(locus name)	psi-mi:trip6(display_short)|psi-mi:EBI-11524292(display_long)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11548047|imex:IM-24995-2715	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000028681|ensemblfungi:YLR347W-A(gene)|ensemblfungi:YLR347W-A_mRNA(transcript)|sgd:YLR347W-A(identity)	entrezgene/locuslink:7205(identity)	-	-	no-uniprot-update:	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/03/16	rogid:eZ3330guTyvylD3kiCyArvlGWGI559292	rogid:S6W5lkNauGhNejln9bTVoqZjNL49606	intact-crc:932C2053E0A525DC|rigid:zt6zAW9KVan93EIdtiZ7tge+kes	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q7LHD1	uniprotkb:Q03393	intact:EBI-11537611	intact:EBI-712344|ensembl:ENSP00000280362|uniprotkb:Q8WVG8|uniprotkb:B0YJ87	psi-mi:ccw22_yeast(display_long)|uniprotkb:CCW22(gene name)|psi-mi:CCW22(display_short)|uniprotkb:YD9302.09C/YD9302.10C(orf name)|uniprotkb:YDR134C(locus name)	psi-mi:ptps_human(display_long)|uniprotkb:PTS(gene name)|psi-mi:PTS(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11548038|imex:IM-24995-2714	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR025928|sgd:S000002541|go:"GO:0005576"(extracellular region)|go:"GO:0009277"(fungal-type cell wall)|go:"GO:0031225"(anchored component of membrane)|sgd:YDR134C(identity)	refseq:NP_000308.1|ensembl:ENSG00000150787(gene)|ensembl:ENST00000280362(transcript)|go:"GO:0003874"(6-pyruvoyltetrahydropterin synthase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006520"(cellular amino acid metabolic process)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0007417"(central nervous system development)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR007115(6-pyruvoyl tetrahydropterin synthase-related)|interpro:IPR022469|interpro:IPR022470|interpro:IPR038418|rcsb pdb:3I2B|reactome:R-HSA-1474151|entrezgene/locuslink:5805(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/03/16	rogid:Jrl6wg+0ObAYQSYzJxhVcNq5QcQ559292	rogid:Qa3bMpzyvRxrvDq9dZUSQlfbpeg9606	intact-crc:D2CA01379DC8C588|rigid:1S3ndMY8ZrXubpp6jreEYD5mcK0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8N6L0	uniprotkb:Q6Q595	intact:EBI-749265|uniprotkb:Q96MC3|ensembl:ENSP00000404220	intact:EBI-2346131|uniprotkb:D6VPR2|ensemblfungi:YBL091C-A	psi-mi:kash5_human(display_long)|uniprotkb:KASH5(gene name)|psi-mi:KASH5(display_short)|uniprotkb:CCDC155(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 155(gene name synonym)|uniprotkb:KASH domain-containing protein 5(gene name synonym)	psi-mi:scs22_yeast(display_long)|uniprotkb:SCS22(gene name)|psi-mi:SCS22(display_short)|uniprotkb:VAP homolog 2(gene name synonym)|uniprotkb:YBL091C-A(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11548027|imex:IM-24995-2713	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_653289.3|ensembl:ENSG00000161609(gene)|ensembl:ENST00000447857(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034397"(telomere localization)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051225"(spindle assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0090172"(microtubule cytoskeleton organization involved in homologous chromosome segregation)|go:"GO:0090220"(chromosome localization to nuclear envelope involved in homologous chromosome segregation)|go:"GO:0090619"(meiotic spindle pole)|interpro:IPR011992(EF-Hand type)|interpro:IPR028168|interpro:IPR028170|interpro:IPR039508|mint:Q8N6L0|rcsb pdb:6R2I|rcsb pdb:6WMF|entrezgene/locuslink:147872(identity)	refseq:NP_009461.2|sgd:S000007228|interpro:IPR000535(Major sperm protein)|interpro:IPR008962(PapD-like)|interpro:IPR016763(Vesicle-associated membrane protein)|interpro:IPR013783(Immunoglobulin-like fold)|ensemblfungi:YBL091C-A(gene)|ensemblfungi:YBL091C-A_mRNA(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008654"(phospholipid biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033149"(FFAT motif binding)|go:"GO:0060304"(regulation of phosphatidylinositol dephosphorylation)|go:"GO:0061817"(endoplasmic reticulum-plasma membrane tethering)|go:"GO:0090158"(endoplasmic reticulum membrane organization)|sgd:YBL091C-A(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Wl9L7AcvDHCZuKjYLn8QgGIbZTc9606	rogid:CEe2fGzBKS+GTm7wv+avSs9DXOU559292	intact-crc:D01FB016D089EA31|rigid:a3ZZyPKBWZv8lo+SV70dEig6Qc0	false	-	sufficient binding region:77-175	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q3E7X9	uniprotkb:Q9NPI6	intact:EBI-2343611|uniprotkb:D6W2M5|uniprotkb:P02380|ensemblfungi:YOR167C	intact:EBI-374238|ensembl:ENSP00000476386|uniprotkb:B4DHN9|uniprotkb:U3KQM8	psi-mi:rs28a_yeast(display_long)|uniprotkb:RPS28A(gene name)|psi-mi:RPS28A(display_short)|uniprotkb:RPS33(gene name synonym)|uniprotkb:RPS33A(gene name synonym)|uniprotkb:S33(gene name synonym)|uniprotkb:YS27(gene name synonym)|uniprotkb:O3600(orf name)|uniprotkb:YOR167C(locus name)|uniprotkb:Small ribosomal subunit protein eS28-A(gene name synonym)	psi-mi:dcp1a_human(display_long)|uniprotkb:DCP1A(gene name)|psi-mi:DCP1A(display_short)|uniprotkb:Transcription factor SMIF(gene name synonym)|uniprotkb:Smad4-interacting transcriptional co-activator(gene name synonym)|uniprotkb:SMIF(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11548018|imex:IM-24995-2712	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014810.1|sgd:S000005693|dip:DIP-29384N|ensemblfungi:YOR167C(gene)|ensemblfungi:YOR167C_mRNA(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0006407"(rRNA export from nucleus)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0030490"(maturation of SSU-rRNA)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|interpro:IPR000289(Ribosomal protein S28e)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR028626|rcsb pdb:3J6X|rcsb pdb:3J6Y|rcsb pdb:3J77|rcsb pdb:3J78|rcsb pdb:4U3M|rcsb pdb:4U3N|rcsb pdb:4U3U|rcsb pdb:4U4N|rcsb pdb:4U4O|rcsb pdb:4U4Q|rcsb pdb:4U4R|rcsb pdb:4U4U|rcsb pdb:4U4Y|rcsb pdb:4U4Z|rcsb pdb:4U50|rcsb pdb:4U51|rcsb pdb:4U52|rcsb pdb:4U53|rcsb pdb:4U55|rcsb pdb:4U56|rcsb pdb:4U6F|rcsb pdb:4V6I|rcsb pdb:4V7R|rcsb pdb:4V88|rcsb pdb:4V8Y|rcsb pdb:4V8Z|rcsb pdb:4V92|rcsb pdb:5DAT|rcsb pdb:5DC3|rcsb pdb:5DGE|rcsb pdb:5DGF|rcsb pdb:5DGV|rcsb pdb:5FCI|rcsb pdb:5FCJ|rcsb pdb:5I4L|rcsb pdb:5JPQ|rcsb pdb:5JUO|rcsb pdb:5JUP|rcsb pdb:5JUS|rcsb pdb:5JUT|rcsb pdb:5JUU|rcsb pdb:5LYB|rcsb pdb:5MEI|rcsb pdb:5NDG|rcsb pdb:5NDV|rcsb pdb:5NDW|rcsb pdb:5OBM|rcsb pdb:5ON6|rcsb pdb:5TBW|rcsb pdb:5TGA|rcsb pdb:5TGM|rcsb pdb:5TZS|rcsb pdb:5WLC|rcsb pdb:5WYJ|rcsb pdb:5WYK|rcsb pdb:6FAI|rcsb pdb:6GQ1|rcsb pdb:6GQB|rcsb pdb:6GQV|rcsb pdb:6HHQ|rcsb pdb:6I7O|rcsb pdb:6KE6|rcsb pdb:6LQP|rcsb pdb:6LQQ|rcsb pdb:6LQR|rcsb pdb:6LQS|rcsb pdb:6LQT|rcsb pdb:6LQU|rcsb pdb:6LQV|rcsb pdb:6Q8Y|rcsb pdb:6RBD|rcsb pdb:6RBE|rcsb pdb:6S47|rcsb pdb:6T4Q|rcsb pdb:6TB3|rcsb pdb:6TNU|rcsb pdb:6WDR|rcsb pdb:6WOO|rcsb pdb:6Y7C|rcsb pdb:6Z6J|rcsb pdb:6Z6K|rcsb pdb:6ZQA|rcsb pdb:6ZQB|rcsb pdb:6ZQC|rcsb pdb:6ZQD|rcsb pdb:6ZQE|rcsb pdb:6ZQF|rcsb pdb:6ZQG|rcsb pdb:6ZVI|rcsb pdb:7A1G|rcsb pdb:7AJT|rcsb pdb:7AJU|rcsb pdb:7B7D|rcsb pdb:7NRC|rcsb pdb:7NRD|sgd:YOR167C(identity)	ensembl:ENSG00000272886(gene)|ensembl:ENST00000610213(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016020"(membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0019894"(kinesin binding)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|interpro:IPR010334(Dcp1-like decapping)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR031953|mint:Q9NPI6|rcsb pdb:2WX3|rcsb pdb:4B6H|reactome:R-HSA-430039|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-975957|refseq:NP_060873.4|refseq:NP_001277133.1|refseq:NP_001277136.1|refseq:NP_001277134.1|refseq:NP_001277135.1|dip:DIP-31292N|entrezgene/locuslink:55802(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2018/09/18	rogid:gvC4obwu3fwLTPwW+gv2KPlZ02A559292	rogid:KIg2pPmAEIiig2SXAJNziN91oCY9606	intact-crc:038F96D65BC8AD56|rigid:vROv6ZoiAAm/VhBjEm6qTGKgggk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O76003	uniprotkb:Q99288	intact:EBI-374781|uniprotkb:Q96CE0|uniprotkb:Q9P1B0|uniprotkb:Q9P1B1|uniprotkb:B3KMP7|uniprotkb:B3KMQ5|uniprotkb:Q5JV01|ensembl:ENSP00000330836|ensembl:ENSP00000357633|ensembl:ENSP00000435445|uniprotkb:D3DRG2	intact:EBI-30580|uniprotkb:Q05314|uniprotkb:P87337|uniprotkb:Q7LHX4|uniprotkb:D6VS38|ensemblfungi:YDR051C	psi-mi:glrx3_human(display_long)|uniprotkb:GLRX3(gene name)|psi-mi:GLRX3(display_short)|uniprotkb:Thioredoxin-like protein 2(gene name synonym)|uniprotkb:PKC-interacting cousin of thioredoxin(gene name synonym)|uniprotkb:PKC-theta-interacting protein(gene name synonym)|uniprotkb:PICOT(gene name synonym)|uniprotkb:HUSSY-22(orf name)|uniprotkb:TXNL2(gene name synonym)	psi-mi:det1_yeast(display_long)|uniprotkb:DET1(gene name)|psi-mi:DET1(display_short)|uniprotkb:D4202(orf name)|uniprotkb:YDR051C(locus name)|uniprotkb:Decreased ergosterol transport protein 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11548120|imex:IM-24995-2723	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000108010(gene)|ensembl:ENST00000331244(transcript)|ensembl:ENST00000368644(transcript)|ensembl:ENST00000481034(transcript)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0003723"(RNA binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0030018"(Z disc)|go:"GO:0030425"(dendrite)|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051536"(iron-sulfur cluster binding)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|go:"GO:0097573"(glutathione oxidoreductase activity)|interpro:IPR002109(Glutaredoxin)|interpro:IPR004480(Glutaredoxin-related protein)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR033658|interpro:IPR036249|mint:O76003|rcsb pdb:2DIY|rcsb pdb:2WZ9|rcsb pdb:2YAN|rcsb pdb:3ZYW|reactome:R-HSA-917937|refseq:NP_001186797.1|refseq:NP_006532.2|dip:DIP-31306N|entrezgene/locuslink:10539(identity)	sgd:S000002458|refseq:NP_010336.3|dip:DIP-1816N|mint:Q99288|ensemblfungi:YDR051C(gene)|ensemblfungi:YDR051C_mRNA(transcript)|go:"GO:0003993"(acid phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016311"(dephosphorylation)|go:"GO:0016791"(phosphatase activity)|go:"GO:0032366"(intracellular sterol transport)|interpro:IPR001345(Phosphoglycerate/bisphosphoglycerate mutase)|interpro:IPR013078(Phosphoglycerate mutase)|interpro:IPR029033|sgd:YDR051C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:iKUSt6zbNzzXSKvW+vXMq3hKsEM9606	rogid:vwXFLCqrDTeOaIJG7tr6C6a1cFs559292	intact-crc:12F4C3CC7B882280|rigid:a92h/SOoY3koogqVQEMXPj4UnsY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q99189	uniprotkb:Q13557-8	intact:EBI-11597|ensemblfungi:YOR160W|uniprotkb:D6W2L7	intact:EBI-11534483|ensembl:ENSP00000296402|ensembl:ENSP00000369098	psi-mi:mtr10_yeast(display_long)|uniprotkb:YOR160W(locus name)|uniprotkb:MTR10(gene name)|psi-mi:MTR10(display_short)	psi-mi:q13557-8(display_long)|uniprotkb:CAMKD(gene name synonym)|uniprotkb:CAMK2D(gene name)|psi-mi:CAMK2D(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11548111|imex:IM-24995-2722	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005737"(cytoplasm)|go:"GO:0006403"(RNA localization)|go:"GO:0006404"(RNA import into nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0034399"(nuclear periphery)|go:"GO:0051031"(tRNA transport)|go:"GO:0061015"(snRNA import into nucleus)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013598(Exportin-1/Importin-beta-like)|interpro:IPR016024(Armadillo-type fold)|ensemblfungi:YOR160W(gene)|ensemblfungi:YOR160W_mRNA(transcript)|go:"GO:0005634"(nucleus)|refseq:NP_014803.1|sgd:S000005686|dip:DIP-2358N|sgd:YOR160W(identity)	intact:EBI-351018(isoform-parent)|ensembl:ENSG00000145349(gene)|ensembl:ENST00000296402(transcript)|ensembl:ENST00000379773(transcript)|uniprotkb:Q13557-8(isoform-parent)|entrezgene/locuslink:817(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:EbfcB0um6KIUegXNsKf6yAD8VRs559292	rogid:44T/I8JdalScCNE5Vp/H+PnfdFo9606	intact-crc:7900763068D8AA44|rigid:coBbrglAnlIAVfwMr7tOu50OVkI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q93062-3	uniprotkb:Q8TGQ8	intact:EBI-740343|ensembl:ENSP00000340176	intact:EBI-11537679|ensemblfungi:YOL085W-A	psi-mi:q93062-3(display_long)|uniprotkb:RBPMS(gene name)|psi-mi:RBPMS(display_short)|uniprotkb:HERMES(gene name synonym)|uniprotkb:Heart and RRM expressed sequence(gene name synonym)	psi-mi:yo85a_yeast(display_long)|uniprotkb:YOL085W-A(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11548102|imex:IM-24995-2721	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-740322(rbpms_human)|uniprotkb:Q93062-3(isoform-parent)|ensembl:ENSG00000157110(gene)|ensembl:ENST00000339877(transcript)|entrezgene/locuslink:11030(identity)	sgd:S000028708|ensemblfungi:YOL085W-A(gene)|ensemblfungi:YOL085W-A_mRNA(transcript)|sgd:YOL085W-A(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/03/16	rogid:nlPMQAJoKEbPYBwsL3xodmCKd7c9606	rogid:kZcPWq9185AwxM/LykJ1Bui6Hvs559292	intact-crc:DF4775541444F8A2|rigid:l4nCtVQGgG4GhFhdK1AAtRyBsHA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96BA8	uniprotkb:Q8TGQ7	intact:EBI-6942903|ensembl:ENSP00000481956|intact:MINT-268046|intact:MINT-8162577|uniprotkb:Q8N2D5|uniprotkb:Q96CP0	intact:EBI-2343396|uniprotkb:D6W4G0|ensemblfungi:YPR159C-A	psi-mi:cr3l1_human(display_long)|uniprotkb:CREB3L1(gene name)|psi-mi:CREB3L1(display_short)|uniprotkb:OASIS(gene name synonym)|uniprotkb:PSEC0238(orf name)|uniprotkb:Old astrocyte specifically-induced substance(gene name synonym)	psi-mi:yp159_yeast(display_long)|uniprotkb:YPR159C-A(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11548093|imex:IM-24995-2720	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157613(gene)|ensembl:ENST00000621158(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0070278"(extracellular matrix constituent secretion)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029805|mint:Q96BA8|reactome:R-HSA-8874211|refseq:NP_443086.1|entrezgene/locuslink:90993(identity)	sgd:S000028725|refseq:NP_878184.1|ensemblfungi:YPR159C-A(gene)|ensemblfungi:YPR159C-A_mRNA(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0016021"(integral component of membrane)|sgd:YPR159C-A(identity)	-	comment:mint|function:"Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE"	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:sMWUFmBeBBCO+T0Y2CuB/un1lBg9606	rogid:QGsci3FKQweBQvaMDdLKyHdq8tM559292	intact-crc:8043A486B70D2070|rigid:DeHYvscpGsKzoayjNN8/HmV97AI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8TGQ7	uniprotkb:Q8N6L0	intact:EBI-2343396|uniprotkb:D6W4G0|ensemblfungi:YPR159C-A	intact:EBI-749265|uniprotkb:Q96MC3|ensembl:ENSP00000404220	psi-mi:yp159_yeast(display_long)|uniprotkb:YPR159C-A(locus name)	psi-mi:kash5_human(display_long)|uniprotkb:KASH5(gene name)|psi-mi:KASH5(display_short)|uniprotkb:CCDC155(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 155(gene name synonym)|uniprotkb:KASH domain-containing protein 5(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11548084|imex:IM-24995-2719	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000028725|refseq:NP_878184.1|ensemblfungi:YPR159C-A(gene)|ensemblfungi:YPR159C-A_mRNA(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0016021"(integral component of membrane)|sgd:YPR159C-A(identity)	refseq:NP_653289.3|ensembl:ENSG00000161609(gene)|ensembl:ENST00000447857(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034397"(telomere localization)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051225"(spindle assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0090172"(microtubule cytoskeleton organization involved in homologous chromosome segregation)|go:"GO:0090220"(chromosome localization to nuclear envelope involved in homologous chromosome segregation)|go:"GO:0090619"(meiotic spindle pole)|interpro:IPR011992(EF-Hand type)|interpro:IPR028168|interpro:IPR028170|interpro:IPR039508|mint:Q8N6L0|rcsb pdb:6R2I|rcsb pdb:6WMF|entrezgene/locuslink:147872(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:QGsci3FKQweBQvaMDdLKyHdq8tM559292	rogid:Wl9L7AcvDHCZuKjYLn8QgGIbZTc9606	intact-crc:AC83EE7B028B358C|rigid:H0Zg9HThbB8YZRiGY2k7psd6gUs	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8TGQ7	uniprotkb:Q12846	intact:EBI-2343396|uniprotkb:D6W4G0|ensemblfungi:YPR159C-A	intact:EBI-744942|uniprotkb:Q15525|ensembl:ENSP00000317714|uniprotkb:Q6FHE8|uniprotkb:A8MXY0	psi-mi:yp159_yeast(display_long)|uniprotkb:YPR159C-A(locus name)	psi-mi:stx4_human(display_long)|uniprotkb:Renal carcinoma antigen NY-REN-31(gene name synonym)|uniprotkb:STX4(gene name)|psi-mi:STX4(display_short)|uniprotkb:STX4A(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11548075|imex:IM-24995-2718	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000028725|refseq:NP_878184.1|ensemblfungi:YPR159C-A(gene)|ensemblfungi:YPR159C-A_mRNA(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0016021"(integral component of membrane)|sgd:YPR159C-A(identity)	ensembl:ENSG00000103496(gene)|refseq:NP_004595.2|ensembl:ENST00000313843(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0000322"(storage vacuole)|go:"GO:0002639"(positive regulation of immunoglobulin production)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005768"(endosome)|go:"GO:0005773"(vacuole)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006887"(exocytosis)|go:"GO:0006906"(vesicle fusion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016230"(sphingomyelin phosphodiesterase activator activity)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0032589"(neuron projection membrane)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035493"(SNARE complex assembly)|go:"GO:0035749"(myelin sheath adaxonal region)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0036477"(somatodendritic compartment)|go:"GO:0042581"(specific granule)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043197"(dendritic spine)|go:"GO:0043219"(lateral loop)|go:"GO:0043311"(positive regulation of eosinophil degranulation)|go:"GO:0045202"(synapse)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0048278"(vesicle docking)|go:"GO:0048284"(organelle fusion)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048787"(presynaptic active zone membrane)|go:"GO:0050921"(positive regulation of chemotaxis)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1902041"(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1903575"(cornified envelope assembly)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|reactome:R-HSA-114516|reactome:R-HSA-1236974|reactome:R-HSA-1445148|reactome:R-HSA-199992|reactome:R-HSA-449836|interpro:IPR006011(Syntaxin, N-terminal)|refseq:NP_001259025.1|entrezgene/locuslink:6810(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:QGsci3FKQweBQvaMDdLKyHdq8tM559292	rogid:NvOLGIGe/XO2aDPSpdPzrtKniZY9606	intact-crc:8B0AE48DD0E95354|rigid:SJ4vQ3B3xUYzq+sCfQ4y92YU6Rk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q15415	uniprotkb:Q99383	intact:EBI-8642021|uniprotkb:B2R916|intact:MINT-8163253|ensembl:ENSP00000250831|ensembl:ENSP00000307155	intact:EBI-11783|uniprotkb:Q02741|ensemblfungi:YOL123W|uniprotkb:D6W1U5	psi-mi:rby1f_human(display_long)|uniprotkb:RBMY1F(gene name)|psi-mi:RBMY1F(display_short)|uniprotkb:RBMY1J(gene name)|psi-mi:RBMY1J(display_short)|uniprotkb:Y chromosome RNA recognition motif 2(gene name synonym)|uniprotkb:YRRM2(gene name synonym)	psi-mi:hrp1_yeast(display_long)|uniprotkb:YOL123W(locus name)|uniprotkb:HRP1(gene name)|psi-mi:HRP1(display_short)|uniprotkb:NAB4(gene name synonym)|uniprotkb:NAB5(gene name synonym)|uniprotkb:Cleavage factor IB(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11548167|imex:IM-24995-2728	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001290339.1|refseq:NP_001006117.2|refseq:NP_689798.1|ensembl:ENSG00000169800(gene)|ensembl:ENSG00000226941(gene)|ensembl:ENST00000250831(transcript)|ensembl:ENST00000303766(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016607"(nuclear speck)|go:"GO:0042802"(identical protein binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012604(RBM1CTR)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|entrezgene/locuslink:159163(identity)	ensemblfungi:YOL123W(gene)|ensemblfungi:YOL123W_mRNA(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005849"(mRNA cleavage factor complex)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0072423"(response to DNA damage checkpoint signaling)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034155|interpro:IPR034156|interpro:IPR035979|rcsb pdb:2CJK|rcsb pdb:2KM8|go:"GO:0005737"(cytoplasm)|refseq:NP_014518.1|sgd:S000005483|dip:DIP-1371N|sgd:YOL123W(identity)	-	comment:mint	crc64:1B231069437B093D	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:lEyv+LmtOFRifaC5g6jDlh5WCnM9606	rogid:8EWzxKR7UWoJhDGSB/0C2d0Qn6k559292	intact-crc:72305B667CE41FCD|rigid:307E09SLKg3CbMqdndHvbV6z96I	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q99383	uniprotkb:P38159	intact:EBI-11783|uniprotkb:Q02741|ensemblfungi:YOL123W|uniprotkb:D6W1U5	intact:EBI-743526|ensembl:ENSP00000359645|uniprotkb:Q5JQ67|uniprotkb:Q969R3|uniprotkb:D3DWH0|uniprotkb:E9PG86|uniprotkb:Q8N8Y7|uniprotkb:B4E3U4	psi-mi:hrp1_yeast(display_long)|uniprotkb:YOL123W(locus name)|uniprotkb:HRP1(gene name)|psi-mi:HRP1(display_short)|uniprotkb:NAB4(gene name synonym)|uniprotkb:NAB5(gene name synonym)|uniprotkb:Cleavage factor IB(gene name synonym)	psi-mi:rbmx_human(display_long)|uniprotkb:Glycoprotein p43(gene name synonym)|uniprotkb:RBMX(gene name)|psi-mi:RBMX(display_short)|uniprotkb:HNRPG(gene name synonym)|uniprotkb:RBMXP1(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein G(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11548158|imex:IM-24995-2727	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YOL123W(gene)|ensemblfungi:YOL123W_mRNA(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005849"(mRNA cleavage factor complex)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0072423"(response to DNA damage checkpoint signaling)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034155|interpro:IPR034156|interpro:IPR035979|rcsb pdb:2CJK|rcsb pdb:2KM8|go:"GO:0005737"(cytoplasm)|refseq:NP_014518.1|sgd:S000005483|dip:DIP-1371N|sgd:YOL123W(identity)	ensembl:ENSG00000147274(gene)|ensembl:ENST00000320676(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000791"(euchromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0044530"(supraspliceosomal complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0006509"(membrane protein ectodomain proteolysis)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012604(RBM1CTR)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|mint:P38159|rcsb pdb:2MB0|rcsb pdb:2MKS|reactome:R-HSA-72163|reactome:R-HSA-72203|reactome:R-HSA-9013418|reactome:R-HSA-9013422|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273|refseq:NP_002130.2|refseq:NP_001158275.1|dip:DIP-34447N|entrezgene/locuslink:27316(identity)	-	crc64:1B231069437B093D	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:8EWzxKR7UWoJhDGSB/0C2d0Qn6k559292	rogid:ocCkdy9PxjeVLUQf0tMVCEhFfO89606	intact-crc:F11B67BB30F4FBE3|rigid:cUrutqqJPJxYJQwe6Pf/PkZWYfc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96EQ0	uniprotkb:Q99380	intact:EBI-744081|ensembl:ENSP00000370395	intact:EBI-12689|uniprotkb:D6VRC4|ensemblfungi:YDL232W	psi-mi:sgtb_human(display_long)|uniprotkb:Beta-SGT(gene name synonym)|uniprotkb:Small glutamine-rich protein with tetratricopeptide repeats 2(gene name synonym)|uniprotkb:SGTB(gene name)|psi-mi:SGTB(display_short)|uniprotkb:SGT2(gene name synonym)	psi-mi:ost4_yeast(display_long)|uniprotkb:OST4(gene name)|psi-mi:OST4(display_short)|uniprotkb:Oligosaccharyl transferase 4 kDa subunit(gene name synonym)|uniprotkb:YDL232W(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11548149|imex:IM-24995-2726	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_061945.1|refseq:XP_005248605.1|ensembl:ENSG00000197860(gene)|ensembl:ENST00000381007(transcript)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0072380"(TRC complex)|go:"GO:1903646"(positive regulation of chaperone-mediated protein folding)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR032374|entrezgene/locuslink:54557(identity)	ensemblfungi:YDL232W(gene)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0008250"(oligosaccharyltransferase complex)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030674"(protein-macromolecule adaptor activity)|interpro:IPR018943|interpro:IPR036330|rcsb pdb:1RKL|rcsb pdb:6C26|rcsb pdb:6EZN|ensemblfungi:YDL232W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|refseq:NP_010049.1|sgd:S000002391|dip:DIP-2457N|sgd:YDL232W(identity)	-	-	crc64:BA14A9C3B197F12A	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:emIgH8U/yVmXT00Ty9yybIqQqas9606	rogid:JOKTdHukiAM2CO87EYm3TT8UxDQ559292	intact-crc:02AA59D16A543770|rigid:gJrsNUC7PlhReDpRaF6wp5nPNLo	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q99380	uniprotkb:O43765	intact:EBI-12689|uniprotkb:D6VRC4|ensemblfungi:YDL232W	intact:EBI-347996|ensembl:ENSP00000221566|ensembl:ENSP00000503397|ensembl:ENSP00000504495|uniprotkb:Q9BTZ9|intact:EBI-1045243|uniprotkb:Q6FIA9|uniprotkb:D6W610	psi-mi:ost4_yeast(display_long)|uniprotkb:OST4(gene name)|psi-mi:OST4(display_short)|uniprotkb:Oligosaccharyl transferase 4 kDa subunit(gene name synonym)|uniprotkb:YDL232W(locus name)	psi-mi:sgta_human(display_long)|uniprotkb:SGTA(gene name)|psi-mi:SGTA(display_short)|uniprotkb:SGT(gene name synonym)|uniprotkb:Alpha-SGT(gene name synonym)|uniprotkb:Vpu-binding protein(gene name synonym)|uniprotkb:SGT1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11548140|imex:IM-24995-2725	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YDL232W(gene)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0008250"(oligosaccharyltransferase complex)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030674"(protein-macromolecule adaptor activity)|interpro:IPR018943|interpro:IPR036330|rcsb pdb:1RKL|rcsb pdb:6C26|rcsb pdb:6EZN|ensemblfungi:YDL232W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|refseq:NP_010049.1|sgd:S000002391|dip:DIP-2457N|sgd:YDL232W(identity)	rcsb pdb:4CPG|rcsb pdb:4GOD|rcsb pdb:4GOE|rcsb pdb:4GOF|reactome:R-HSA-9609523|rcsb pdb:2VYI|ensembl:ENSG00000104969(gene)|ensembl:ENST00000221566(transcript)|ensembl:ENST00000676943(transcript)|ensembl:ENST00000677149(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072380"(TRC complex)|go:"GO:0098850"(extrinsic component of synaptic vesicle membrane)|go:"GO:1903070"(negative regulation of ER-associated ubiquitin-dependent protein catabolic process)|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)|go:"GO:1903646"(positive regulation of chaperone-mediated protein folding)|go:"GO:1904288"(BAT3 complex binding)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR032374|mint:O43765|refseq:XP_011526480.1|refseq:NP_003012.1|entrezgene/locuslink:6449(identity)	-	crc64:BA14A9C3B197F12A	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:JOKTdHukiAM2CO87EYm3TT8UxDQ559292	rogid:r/Cyj4UJk/cS8QdrbjhTZMPCigI9606	intact-crc:658ABC2366497CA5|rigid:AZC00OrV2+nxyUj43yl1ONPojW4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9Y2J4	uniprotkb:Q99344	intact:EBI-746752|intact:EBI-28986657|ensembl:ENSP00000409999|uniprotkb:Q53EP1|uniprotkb:Q96F99|uniprotkb:Q9UKB4|uniprotkb:A8K6F1|uniprotkb:B7Z5Q1|uniprotkb:E9PHW3	intact:EBI-37997|uniprotkb:D6W470|uniprotkb:E9P8X1|ensemblfungi:YPR066W	psi-mi:amol2_human(display_long)|uniprotkb:Leman coiled-coil protein(gene name synonym)|uniprotkb:AMOTL2(gene name)|psi-mi:AMOTL2(display_short)|uniprotkb:KIAA0989(gene name synonym)	psi-mi:uba3_yeast(display_long)|uniprotkb:Ubiquitin-activating enzyme E1 3(gene name synonym)|uniprotkb:RUB1-activating enzyme E1(gene name synonym)|uniprotkb:Ubiquitin-like protein-activating enzyme(gene name synonym)|uniprotkb:UBA3(gene name)|psi-mi:UBA3(display_short)|uniprotkb:YPR066W(locus name)|uniprotkb:YP9499.21(orf name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11548129|imex:IM-24995-2724	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001265612.1|refseq:NP_001265614.1|ensembl:ENSG00000114019(gene)|refseq:XP_006713717.1|refseq:NP_057285.3|refseq:XP_011511183.1|ensembl:ENST00000422605(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0003365"(establishment of cell polarity involved in ameboidal cell migration)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0035329"(hippo signaling)|go:"GO:0055037"(recycling endosome)|interpro:IPR009114(Angiomotin)|interpro:IPR024646|mint:Q9Y2J4|reactome:R-HSA-2028269|refseq:XP_016862069.1|refseq:XP_016862070.1|refseq:XP_016862071.1|ensembl:ENST00000249883|ensembl:ENSP00000249883|ensembl:ENSP00000409999|ensembl:ENST00000513145|ensembl:ENSP00000425475|ensembl:ENST00000514516|ensembl:ENSP00000424765|dip:DIP-57510N|entrezgene/locuslink:51421(identity)	refseq:NP_015391.1|sgd:S000006270|ensemblfungi:YPR066W(gene)|ensemblfungi:YPR066W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0019781"(NEDD8 activating enzyme activity)|go:"GO:0032446"(protein modification by small protein conjugation)|go:"GO:0045116"(protein neddylation)|interpro:IPR000594(UBA/THIF-type NAD/FAD binding fold)|interpro:IPR023318|interpro:IPR030468|interpro:IPR033127|dip:DIP-1719N|interpro:IPR035985|reactome:R-SCE-983168|sgd:YPR066W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:SHtKAcLLnTpSSLwVE7yQ1WECoZk9606	rogid:W38WpbRWXZjHVLC7ECqtRkmDBpI559292	intact-crc:65F38A3778074CBA|rigid:W4gM1LLSUF8w2gQk797gpk3Abkc	false	sufficient binding region:314-779	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:G5E962	uniprotkb:Q9URQ5	intact:EBI-11525615|ensembl:ENSP00000328177	intact:EBI-8717|ensemblfungi:YCR020W-B|uniprotkb:D6VR30	psi-mi:g5e962_human(display_long)|uniprotkb:hCG_1644200(orf name)|uniprotkb:MAGEA11(gene name)|psi-mi:MAGEA11(display_short)	psi-mi:htl1_yeast(display_long)|uniprotkb:YCR020W-B(locus name)|uniprotkb:HTL1(gene name)|psi-mi:HTL1(display_short)|uniprotkb:DRT1(gene name synonym)|uniprotkb:Chromatin structure-remodeling complex protein HTL1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11548176|imex:IM-24995-2729	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001011544.1|ensembl:ENSG00000185247(gene)|ensembl:ENST00000333104(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016604"(nuclear body)|interpro:IPR002190(MAGE protein)|interpro:IPR021072|interpro:IPR030099|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|entrezgene/locuslink:4110(identity)	go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016586"(RSC-type complex)|rcsb pdb:6K15|rcsb pdb:6KW3|rcsb pdb:6KW4|rcsb pdb:6KW5|rcsb pdb:6TDA|rcsb pdb:6V8O|ensemblfungi:YCR020W-B(gene)|ensemblfungi:YCR020W-B_mRNA(transcript)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0005634"(nucleus)|rcsb pdb:6V92|refseq:NP_009949.1|sgd:S000006439|mint:Q9URQ5|sgd:YCR020W-B(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:sVB0aA6yibWUx/d2SE+pwpKKgtI9606	rogid:Le5HdUusNnY+/Cgn/WyISowVdbs559292	intact-crc:BE7242743A5C84C4|rigid:MnNibLqcnWogRNb0/1fThCATswY	false	sufficient binding region:82-400	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q5T124-6	uniprotkb:P32502	intact:EBI-11524408	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:q5t124-6(display_long)|uniprotkb:UBXN11(gene name)|psi-mi:UBXN11(display_short)|uniprotkb:Colorectal tumor-associated antigen COA-1(gene name synonym)|uniprotkb:SOC(gene name synonym)|uniprotkb:Socius(gene name synonym)|uniprotkb:UBX domain-containing protein 5(gene name synonym)|uniprotkb:UBXD5(gene name synonym)|uniprotkb:PP2243(orf name)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11555297|imex:IM-24995-4393	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-746004(isoform-parent)|uniprotkb:Q5T124-6(isoform-parent)|entrezgene/locuslink:91544(identity)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	-	-	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:1YSjG/p2ihcjl4P8KdPCaX2HxiY9606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:83EF9BC3F152FD66|rigid:TCELETJrv2CLPOCOuIEVqKThbSA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8IYA8	uniprotkb:P32502	intact:EBI-8638439|intact:EBI-28969497|ensembl:ENSP00000296449|ensembl:ENSP00000391788|ensembl:ENSP00000407837|uniprotkb:C9JJL0|uniprotkb:Q96LP7|intact:MINT-8162095|uniprotkb:Q05DG9	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:iho1_human(display_long)|uniprotkb:IHO1(gene name)|psi-mi:IHO1(display_short)|uniprotkb:CCDC36(gene name synonym)|uniprotkb:Cancer/testis antigen 74(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 36(gene name synonym)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11555335|imex:IM-24995-4397	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000296449|ensembl:ENST00000366429|ensembl:ENSP00000403700|ensembl:ENSP00000391788|ensembl:ENSP00000407837|ensembl:ENSG00000173421(gene)|ensembl:ENST00000296449(transcript)|ensembl:ENST00000438782(transcript)|ensembl:ENST00000452691(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0006310"(DNA recombination)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0042138"(meiotic DNA double-strand break formation)|go:"GO:0048477"(oogenesis)|go:"GO:0060629"(regulation of homologous chromosome segregation)|interpro:IPR031529|mint:Q8IYA8|refseq:XP_011531974.1|refseq:XP_011531975.1|refseq:NP_001128669.1|refseq:NP_835467.2|refseq:XP_006713187.1|entrezgene/locuslink:339834(identity)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	-	comment:mint	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:+TNQLExkhmC1NWqsE240Cx7zFVU9606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:B83670502047E674|rigid:aD6ReVsQ4vnRgoWlg+1OttnqWGc	false	sufficient binding region:11-594	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32502	uniprotkb:Q8IUQ4-2	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	intact:EBI-11522811|ensembl:ENSP00000349156	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:q8iuq4-2(display_long)|uniprotkb:SIAH1(gene name)|psi-mi:SIAH1(display_short)|uniprotkb:HUMSIAH(gene name synonym)|uniprotkb:Seven in absentia homolog 1(gene name synonym)|uniprotkb:Siah-1a(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase SIAH1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11555324|imex:IM-24995-4396	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	intact:EBI-747107(isoform-parent)|ensembl:ENSG00000196470(gene)|ensembl:ENST00000356721(transcript)|uniprotkb:Q8IUQ4-2(isoform-parent)|entrezgene/locuslink:6477(identity)	-	crc64:A5409FAF1594854C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	rogid:M4q06jVbWuq1mGMXvtuFBaMEgZM9606	intact-crc:BF6E1DA3126234EF|rigid:Jfgb2nu4MWuYBnqsnt63a0IKQZw	false	-	sufficient binding region:32-313	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32502	uniprotkb:Q86WT6-2	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	intact:EBI-11525489|ensembl:ENSP00000342922|ensembl:ENSP00000479720	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:q86wt6-2(display_long)|uniprotkb:RING-type E3 ubiquitin transferase TRIM69(gene name synonym)|uniprotkb:TRIM69(gene name)|psi-mi:TRIM69(display_short)|uniprotkb:RFP-like domain-containing protein trimless(gene name synonym)|uniprotkb:RING finger protein 36(gene name synonym)|uniprotkb:RNF36(gene name synonym)|uniprotkb:Tripartite motif-containing protein 69(gene name synonym)|uniprotkb:HSD-34(orf name)|uniprotkb:HSD34(orf name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11555315|imex:IM-24995-4395	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	intact:EBI-749955(isoform-parent)|uniprotkb:Q86WT6-2(isoform-parent)|ensembl:ENSG00000185880(gene)|ensembl:ENSG00000278211(gene)|ensembl:ENST00000338264(transcript)|ensembl:ENST00000618398(transcript)|entrezgene/locuslink:140691(identity)	-	crc64:A5409FAF1594854C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	rogid:J0mzn4PSX5vWZqt4X3Ee1Wxx5hw9606	intact-crc:B1B88C50D2B5064B|rigid:LgqfhMLw94zWouczTI/WdTVZE4c	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32502	uniprotkb:Q5VSY0	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	intact:EBI-743722|uniprotkb:Q9BYI2|uniprotkb:Q96LI0|uniprotkb:Q9BYI1|uniprotkb:Q9H225|ensembl:ENSP00000365550	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:gkap1_human(display_long)|uniprotkb:GKAP42(gene name synonym)|uniprotkb:cGMP-dependent protein kinase-anchoring protein of 42 kDa(gene name synonym)|uniprotkb:FKSG21(orf name)|uniprotkb:GKAP1(gene name)|psi-mi:GKAP1(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11555306|imex:IM-24995-4394	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	ensembl:ENSG00000165113(gene)|refseq:NP_001129425.1|refseq:NP_079487.2|refseq:XP_011517360.1|refseq:XP_005252298.1|ensembl:ENST00000376371(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0007165"(signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|interpro:IPR026109|dip:DIP-47324N|entrezgene/locuslink:80318(identity)	-	crc64:A5409FAF1594854C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	rogid:WPAqDDTftv300tbwXkusTo6tmUo9606	intact-crc:BD56F50043E120C9|rigid:CoAQLd/ljLQV7hG1azX99tfKnaI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8TAP6	uniprotkb:P32502	intact:EBI-742887|ensembl:ENSP00000262127|uniprotkb:Q658N5|uniprotkb:Q9H9U7|uniprotkb:B0YJB2|uniprotkb:B4DXG5|uniprotkb:B4DZW1	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:cep76_human(display_long)|uniprotkb:CEP76(gene name)|psi-mi:CEP76(display_short)|uniprotkb:C18orf9(gene name synonym)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11555402|imex:IM-24995-4404	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_079175.2|ensembl:ENSG00000101624(gene)|ensembl:ENST00000262127(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0046599"(regulation of centriole replication)|interpro:IPR028926|interpro:IPR038765|mint:Q8TAP6|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_001258918.1|entrezgene/locuslink:79959(identity)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	-	-	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:fWzb8oIU35oVWomyDrf8u5sbxUk9606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:F88D57537423FD3C|rigid:xIEW9O53WNj98bB1gVHS61fa9CM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32502	uniprotkb:Q8NHQ1-3	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	intact:EBI-11526150|ensembl:ENSP00000419743	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:q8nhq1-3(display_long)|uniprotkb:CEP70(gene name)|psi-mi:CEP70(display_short)|uniprotkb:BITE(gene name synonym)|uniprotkb:p10-binding protein(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11555393|imex:IM-24995-4403	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	ensembl:ENSG00000114107(gene)|ensembl:ENST00000464035(transcript)|intact:EBI-739624(isoform-parent)|uniprotkb:Q8NHQ1-3(isoform-parent)|entrezgene/locuslink:80321(identity)	-	crc64:A5409FAF1594854C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	rogid:hoF4iYo+GzWQ21hoaWZfTftWKCc9606	intact-crc:7C4084690FC888C6|rigid:gvbOoDyvh55QDtfHDRmfUJrq5uI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32502	uniprotkb:Q8NHQ1	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	intact:EBI-739624|ensembl:ENSP00000264982|ensembl:ENSP00000419231|uniprotkb:Q96B31|uniprotkb:Q9H2C3|uniprotkb:Q9H2Z1|uniprotkb:Q9H940|uniprotkb:D3DNE9|uniprotkb:B7Z5I8|uniprotkb:B7Z7E8|uniprotkb:F5GZX8	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:cep70_human(display_long)|uniprotkb:CEP70(gene name)|psi-mi:CEP70(display_short)|uniprotkb:BITE(gene name synonym)|uniprotkb:p10-binding protein(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11555384|imex:IM-24995-4402	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	ensembl:ENSG00000114107(gene)|ensembl:ENST00000264982(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|interpro:IPR019734|interpro:IPR037692|mint:Q8NHQ1|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|ensembl:ENST00000484888(transcript)|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_077817.2|refseq:XP_016862764.1|refseq:NP_001275893.1|refseq:NP_001275894.1|refseq:NP_001275895.1|refseq:NP_001275896.1|refseq:NP_001307527.1|refseq:NP_001307529.1|entrezgene/locuslink:80321(identity)	-	crc64:A5409FAF1594854C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	rogid:S4yveQWcvdVtAUX65gqrJ5Dv0Mc9606	intact-crc:75FF13ABFB851EC4|rigid:wsx4pXsjZLscupso/4I0ctieg94	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8NFF5-2	uniprotkb:P32502	intact:EBI-11526128|ensembl:ENSP00000317296	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:q8nff5-2(display_long)|uniprotkb:FLAD1(gene name)|psi-mi:FLAD1(display_short)|uniprotkb:FAD pyrophosphorylase(gene name synonym)|uniprotkb:FMN adenylyltransferase(gene name synonym)|uniprotkb:Flavin adenine dinucleotide synthase(gene name synonym)|uniprotkb:PP591(orf name)|uniprotkb:FADS2(isoform synonym)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11555375|imex:IM-24995-4401	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:Q8NFF5-2(isoform-parent)|intact:EBI-742815(isoform-parent)|ensembl:ENST00000315144(transcript)|ensembl:ENSG00000160688(gene)|entrezgene/locuslink:80308(identity)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	-	-	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:BU/WYJYTvm8VgRPN+e8jjYiw5yU9606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:FB8F1CE893433D1F|rigid:LLyV3rv2PbU1E8qBienKt/ARbcE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8NA82	uniprotkb:P32502	intact:EBI-2341554|uniprotkb:D3DU09|uniprotkb:Q8N7Z7|uniprotkb:Q8IYS7|ensembl:ENSP00000311496|ensembl:ENSP00000416177	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:marha_human(display_long)|uniprotkb:MARCHF10(gene name)|psi-mi:MARCHF10(display_short)|uniprotkb:MARCH10(gene name synonym)|uniprotkb:Membrane-associated RING finger protein 10(gene name synonym)|uniprotkb:Membrane-associated RING-CH protein X(gene name synonym)|uniprotkb:RING finger protein 190(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase MARCHF10(gene name synonym)|uniprotkb:RNF190(gene name synonym)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11555364|imex:IM-24995-4400	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001094345.1|refseq:NP_689811.2|refseq:NP_001275708.1|refseq:NP_001275709.1|ensembl:ENSG00000173838(gene)|ensembl:ENST00000311269(transcript)|ensembl:ENST00000456609(transcript)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016740"(transferase activity)|interpro:IPR011016(Zinc finger, variant RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR042583|entrezgene/locuslink:162333(identity)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	-	-	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:xYNhVYIVxXneNrLbdaSO0uTK9l89606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:B28D7D11E4E88C01|rigid:3K6aRt9u5yZ2AdstYQGOqazRuOY	false	sufficient binding region:1-657	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8NA61-2	uniprotkb:P32502	intact:EBI-11524851|ensembl:ENSP00000368249|ensembl:ENSP00000480148	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:q8na61-2(display_long)|uniprotkb:CBY2(gene name)|psi-mi:CBY2(display_short)|uniprotkb:SPERT(gene name synonym)|uniprotkb:Spermatid-associated protein(gene name synonym)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11555355|imex:IM-24995-4399	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-741724(isoform-parent)|ensembl:ENSG00000174015(gene)|ensembl:ENST00000378966(transcript)|ensembl:ENST00000610924(transcript)|uniprotkb:Q8NA61-2(isoform-parent)|entrezgene/locuslink:220082(identity)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	-	-	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:SogYcXGGMYRYzB9xKC5o0pEtsDs9606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:5F29E1407B9669CA|rigid:1B4D21kYGCv/Xe0aARbP71v8ZGY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8N6L0	uniprotkb:P32502	intact:EBI-749265|uniprotkb:Q96MC3|ensembl:ENSP00000404220	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:kash5_human(display_long)|uniprotkb:KASH5(gene name)|psi-mi:KASH5(display_short)|uniprotkb:CCDC155(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 155(gene name synonym)|uniprotkb:KASH domain-containing protein 5(gene name synonym)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11555346|imex:IM-24995-4398	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_653289.3|ensembl:ENSG00000161609(gene)|ensembl:ENST00000447857(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034397"(telomere localization)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051225"(spindle assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0090172"(microtubule cytoskeleton organization involved in homologous chromosome segregation)|go:"GO:0090220"(chromosome localization to nuclear envelope involved in homologous chromosome segregation)|go:"GO:0090619"(meiotic spindle pole)|interpro:IPR011992(EF-Hand type)|interpro:IPR028168|interpro:IPR028170|interpro:IPR039508|mint:Q8N6L0|rcsb pdb:6R2I|rcsb pdb:6WMF|entrezgene/locuslink:147872(identity)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	-	-	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Wl9L7AcvDHCZuKjYLn8QgGIbZTc9606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:79A92E7CC3EFBD1B|rigid:2JxAFY6iMFYY2m55YCnuCUYq+lE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96EY1-3	uniprotkb:P32502	intact:EBI-11526226|ensembl:ENSP00000393970	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:q96ey1-3(display_long)|uniprotkb:DnaJ protein Tid-1(gene name synonym)|uniprotkb:HCA57(gene name synonym)|uniprotkb:Hepatocellular carcinoma-associated antigen 57(gene name synonym)|uniprotkb:TID1(gene name synonym)|uniprotkb:Tumorous imaginal discs protein Tid56 homolog(gene name synonym)|uniprotkb:DNAJA3(gene name)|psi-mi:DNAJA3(display_short)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11555465|imex:IM-24995-4411	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-356767(isoform-parent)|ensembl:ENSG00000103423(gene)|ensembl:ENST00000431375(transcript)|uniprotkb:Q96EY1-3(isoform-parent)|entrezgene/locuslink:9093(identity)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	-	isoform-comment:"Ref.3 (BAG58345) sequence is in conflict in position: 33:Y->H."	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:nMH4IaOZYO5w5bh+cdX4LoPSisc9606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:D4304F12481A43E9|rigid:aTXYAL3WN3g4e2tWaFZyCDv0gP0	false	sufficient binding region:60-300	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96CG3	uniprotkb:P32502	intact:EBI-740711|ensembl:ENSP00000354911|ensembl:ENSP00000424231	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:tifa_human(display_long)|uniprotkb:Putative NF-kappa-B-activating protein 20(gene name synonym)|uniprotkb:TIFA(gene name)|psi-mi:TIFA(display_short)|uniprotkb:T2BP(gene name synonym)|uniprotkb:TRAF2-binding protein(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM14(gene name synonym)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11555456|imex:IM-24995-4410	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_443096.1|ensembl:ENSG00000145365(gene)|ensembl:ENST00000361717(transcript)|ensembl:ENST00000500655(transcript)|go:"GO:0002753"(cytoplasmic pattern recognition receptor signaling pathway)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0051260"(protein homooligomerization)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR033621|rcsb pdb:4YM4|rcsb pdb:4ZGI|rcsb pdb:5ZUJ|rcsb pdb:6A33|reactome:R-HSA-9645460|dip:DIP-40185N|entrezgene/locuslink:92610(identity)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	-	-	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:ppKFaTK8YYWSscDQlE1n/mONziY9606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:588F2ECE7BD1BBA6|rigid:2KA272tjgq17guvrGjv0gA6SP4E	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96CD2	uniprotkb:P32502	intact:EBI-724333|uniprotkb:Q96SX0|ensembl:ENSP00000343190|uniprotkb:Q9HC17	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:coac_human(display_long)|uniprotkb:CoaC(gene name synonym)|uniprotkb:PPCDC(gene name)|psi-mi:PPCDC(display_short)|uniprotkb:COAC(gene name synonym)|uniprotkb:MDS018(orf name)|uniprotkb:UNQ9365/PRO34154(orf name)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11555447|imex:IM-24995-4409	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_068595.3|rcsb pdb:1QZU|reactome:R-HSA-196783|mint:Q96CD2|ensembl:ENSG00000138621(gene)|ensembl:ENST00000342932(transcript)|go:"GO:0004633"(phosphopantothenoylcysteine decarboxylase activity)|go:"GO:0005829"(cytosol)|go:"GO:0010181"(FMN binding)|go:"GO:0015937"(coenzyme A biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0071513"(phosphopantothenoylcysteine decarboxylase complex)|interpro:IPR003382(Flavoprotein)|interpro:IPR036551|refseq:NP_001288030.1|refseq:NP_001288031.1|refseq:NP_001288032.1|refseq:NP_001288033.1|refseq:NP_001288034.1|entrezgene/locuslink:60490(identity)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	-	-	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:2d686R1m4jA5uWpf/8O6rI6/Olo9606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:A331B6F8958C0DF2|rigid:bGg5IRa1rTNv8sVIwXENQbKQ60M	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32502	uniprotkb:Q96BR9	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	intact:EBI-742740|uniprotkb:Q8IUL5|uniprotkb:Q8IWR9|uniprotkb:Q8N2Y5|uniprotkb:Q96BX0|ensembl:ENSP00000362609	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:zbt8a_human(display_long)|uniprotkb:ZBTB8A(gene name)|psi-mi:ZBTB8A(display_short)|uniprotkb:BOZF1(gene name synonym)|uniprotkb:BTB/POZ and zinc-finger domain-containing factor(gene name synonym)|uniprotkb:BTB/POZ and zinc-finger domains factor on chromosome 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11555438|imex:IM-24995-4408	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	ensembl:ENSG00000160062(gene)|ensembl:ENST00000373510(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|refseq:NP_001035531.2|refseq:NP_001278425.1|entrezgene/locuslink:653121(identity)	-	crc64:A5409FAF1594854C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	rogid:tsrPT2tHvuBryODKgRXnceXz9s09606	intact-crc:4322DA9D324E4667|rigid:pGUYzMu13b6NYTUZKoG4AcVut4o	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32502	uniprotkb:Q96AT9	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	intact:EBI-372480|uniprotkb:O43767|uniprotkb:Q8N215|uniprotkb:Q96N34|uniprotkb:Q9BSB5|uniprotkb:B4E016|ensembl:ENSP00000352401|uniprotkb:A8K4S0|uniprotkb:C9JPQ7|uniprotkb:Q53TV9	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:rpe_human(display_long)|uniprotkb:Ribulose-5-phosphate-3-epimerase(gene name synonym)|uniprotkb:RPE(gene name)|psi-mi:RPE(display_short)|uniprotkb:HUSSY-17(orf name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11555429|imex:IM-24995-4407	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	ensembl:ENSG00000197713(gene)|ensembl:ENST00000359429(transcript)|go:"GO:0004750"(D-ribulose-phosphate 3-epimerase activity)|go:"GO:0005829"(cytosol)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006098"(pentose-phosphate shunt)|go:"GO:0009052"(pentose-phosphate shunt, non-oxidative branch)|go:"GO:0019323"(pentose catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044262"(cellular carbohydrate metabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000056(Ribulose-phosphate 3-epimerase)|interpro:IPR011060(Ribulose-phosphate binding barrel)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR026019|rcsb pdb:3OVP|rcsb pdb:3OVQ|rcsb pdb:3OVR|rcsb pdb:3QC3|reactome:R-HSA-71336|refseq:NP_008847.1|refseq:NP_954699.1|refseq:NP_001305855.1|refseq:NP_001305856.1|refseq:NP_001305857.1|refseq:NP_001305858.1|refseq:NP_001305859.1|refseq:NP_001305860.1|refseq:NP_001265211.1|refseq:NP_001265212.1|refseq:NP_001265214.1|refseq:NP_001265215.1|refseq:NP_001265217.1|refseq:NP_001265218.1|refseq:XP_006712740.1|entrezgene/locuslink:6120(identity)	-	crc64:A5409FAF1594854C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	rogid:lFQZZpLsSKKpUv9o+wSEvPlqG989606	intact-crc:887BA1A8AB8E7D8F|rigid:pD+x8gZiGJrTozR0guYJRc/6Mgs	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32502	uniprotkb:Q969V4	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	intact:EBI-10180409|uniprotkb:D3DTM7|ensembl:ENSP00000341346	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:tekt1_human(display_long)|uniprotkb:TEKT1(gene name)|psi-mi:TEKT1(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11555420|imex:IM-24995-4406	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	refseq:NP_444515.1|ensembl:ENSG00000167858(gene)|ensembl:ENST00000338694(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0031514"(motile cilium)|go:"GO:0060271"(cilium assembly)|go:"GO:0060294"(cilium movement involved in cell motility)|interpro:IPR000435(Tektin)|entrezgene/locuslink:83659(identity)	-	crc64:A5409FAF1594854C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	rogid:5hh7T1hcmqrmmiOtJTT1OokmPrU9606	intact-crc:373BA9016A632020|rigid:WCtLXYrTqxxPifGCBEDTzthl8bg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32502	uniprotkb:Q8WXE1-3	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	intact:EBI-11524582|ensembl:ENSP00000400930	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:q8wxe1-3(display_long)|uniprotkb:ATRIP(gene name)|psi-mi:ATRIP(display_short)|uniprotkb:AGS1(gene name synonym)|uniprotkb:ATM and Rad3-related-interacting protein(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11555411|imex:IM-24995-4405	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	intact:EBI-747353(isoform-parent)|ensembl:ENSG00000164053(gene)|ensembl:ENST00000412052(transcript)|entrezgene/locuslink:84126(identity)	-	crc64:A5409FAF1594854C	isoform-comment:No experimental confirmation available.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	rogid:NKCjy1jGZEySEhUOf8rJ6h9pyxY9606	intact-crc:B5B77BEBE0EF75CB|rigid:8PRM6TuIS7PPBbI7W0s2tbT/MLs	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32502	uniprotkb:Q9NQC3-3	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	intact:EBI-11526335|ensembl:ENSP00000378107	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:q9nqc3-3(display_long)|uniprotkb:Foocen(gene name synonym)|uniprotkb:KIAA0886(gene name synonym)|uniprotkb:NOGO(gene name synonym)|uniprotkb:Neurite outgrowth inhibitor(gene name synonym)|uniprotkb:Neuroendocrine-specific protein(gene name synonym)|uniprotkb:Neuroendocrine-specific protein C homolog(gene name synonym)|uniprotkb:RTN-x(gene name synonym)|uniprotkb:Reticulon-5(gene name synonym)|uniprotkb:My043(orf name)|uniprotkb:SP1507(orf name)|uniprotkb:Foocen-S(isoform synonym)|uniprotkb:Nogo-C(isoform synonym)|uniprotkb:RTN4(gene name)|psi-mi:RTN4(display_short)|uniprotkb:RTN4C(isoform synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11555568|imex:IM-24995-4422	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	intact:EBI-715945(isoform-parent)|ensembl:ENSG00000115310(gene)|ensembl:ENST00000394609(transcript)|entrezgene/locuslink:57142(identity)	-	crc64:A5409FAF1594854C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	rogid:Iq/LlFtXjFyIIfxZ1l3NTKURpyA9606	intact-crc:28E7F9F327CC210E|rigid:vyF0xIDaWGKzxa2afM0/ZpIdraI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32502	uniprotkb:Q9NPJ6	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	intact:EBI-394607|uniprotkb:Q9BS95|uniprotkb:Q9NYR5|uniprotkb:Q53GB4|uniprotkb:Q53H68|uniprotkb:Q5T912|uniprotkb:Q6FHC4|uniprotkb:Q6IA79|uniprotkb:B4DX67|ensembl:ENSP00000258648	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:med4_human(display_long)|uniprotkb:HSPC126(orf name)|uniprotkb:DRIP36(gene name synonym)|uniprotkb:MED4(gene name)|psi-mi:MED4(display_short)|uniprotkb:ARC36(gene name synonym)|uniprotkb:Mediator complex subunit 4(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex 36 kDa component(gene name synonym)|uniprotkb:Activator-recruited cofactor 36 kDa component(gene name synonym)|uniprotkb:TRAP/SMCC/PC2 subunit p36 subunit(gene name synonym)|uniprotkb:VDRIP(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11555559|imex:IM-24995-4421	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	refseq:NP_001257558.1|refseq:NP_054885.1|ensembl:ENSG00000136146(gene)|ensembl:ENST00000258648(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0070847"(core mediator complex)|interpro:IPR019258|mint:Q9NPJ6|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|entrezgene/locuslink:29079(identity)	-	crc64:A5409FAF1594854C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	rogid:Bept2Oec50gruA9e4pf+eEUiANM9606	intact-crc:4D248ABA503D1E19|rigid:+53+PRs9H9BVSg/T98CNrYqG7DA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32502	uniprotkb:Q9H773	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	intact:EBI-723569|intact:EBI-1384169|ensembl:ENSP00000322524	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:dctp1_human(display_long)|uniprotkb:DCTPP1(gene name)|psi-mi:DCTPP1(display_short)|uniprotkb:RS21C6(gene name synonym)|uniprotkb:CDA03(orf name)|uniprotkb:XTP3TPA(gene name synonym)|uniprotkb:Deoxycytidine-triphosphatase 1(gene name synonym)|uniprotkb:XTP3-transactivated gene A protein(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11555550|imex:IM-24995-4420	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	refseq:NP_077001.1|ensembl:ENST00000319285(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006253"(dCTP catabolic process)|go:"GO:0009143"(nucleoside triphosphate catabolic process)|go:"GO:0032556"(pyrimidine deoxyribonucleotide binding)|go:"GO:0042262"(DNA protection)|go:"GO:0042802"(identical protein binding)|go:"GO:0047429"(nucleoside-triphosphate diphosphatase activity)|go:"GO:0047840"(dCTP diphosphatase activity)|interpro:IPR025984|mint:Q9H773|reactome:R-HSA-499943|ensembl:ENSG00000179958(gene)|entrezgene/locuslink:79077(identity)	-	crc64:A5409FAF1594854C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	rogid:4EfV2ZU2MgDiFXShthfualZnat09606	intact-crc:9F97582EEA7D8FAF|rigid:prSEHirUfm6oCGHNCI6tZroyySY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9H0E2	uniprotkb:P32502	intact:EBI-74615|ensembl:ENSP00000314733|uniprotkb:Q9H9E6|uniprotkb:Q9UJ69|uniprotkb:B3KXC6	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:tolip_human(display_long)|uniprotkb:TOLLIP(gene name)|psi-mi:TOLLIP(display_short)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11555541|imex:IM-24995-4419	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000078902(gene)|ensembl:ENST00000317204(transcript)|go:"GO:0005150"(interleukin-1, type I receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006914"(autophagy)|go:"GO:0007165"(signal transduction)|go:"GO:0016310"(phosphorylation)|go:"GO:0016604"(nuclear body)|go:"GO:0019900"(kinase binding)|go:"GO:0006954"(inflammatory response)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032183"(SUMO binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0035580"(specific granule lumen)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045321"(leukocyte activation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070498"(interleukin-1-mediated signaling pathway)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR009060(UBA-like)|interpro:IPR035892|interpro:IPR037301|interpro:IPR041799|rcsb pdb:1WGL|rcsb pdb:2N31|reactome:R-HSA-6798695|reactome:R-HSA-9020702|refseq:NP_061882.2|refseq:NP_001305441.1|refseq:NP_001305443.1|refseq:NP_001305444.1|refseq:NP_001305445.1|dip:DIP-30845N|entrezgene/locuslink:54472(identity)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	-	-	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:HR6/CGVYMtuDqxW44fBD/KjScnk9606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:B10FEDEA3CB28BF1|rigid:10OUQ1rGrklUcPLFH/qVdVfhXPU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32502	uniprotkb:Q9BQD3	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	intact:EBI-739657|uniprotkb:O76098|ensembl:ENSP00000472678|ensembl:ENSP00000472836|ensembl:ENSP00000222307|ensembl:ENSP00000438903|ensembl:ENSP00000443549|ensembl:ENSP00000468990|ensembl:ENSP00000471554	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:kxdl1_human(display_long)|uniprotkb:KXD1(gene name)|psi-mi:KXD1(display_short)|uniprotkb:C19orf50(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11555532|imex:IM-24995-4418	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	refseq:NP_001165419.1|refseq:NP_001165420.1|refseq:NP_076974.2|ensembl:ENST00000222307(transcript)|ensembl:ENST00000539106(transcript)|ensembl:ENST00000540691(transcript)|ensembl:ENST00000595073(transcript)|ensembl:ENST00000599319(transcript)|ensembl:ENST00000600654(transcript)|ensembl:ENST00000602094(transcript)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0032418"(lysosome localization)|go:"GO:0099078"(BORC complex)|interpro:IPR019371|interpro:IPR039843|ensembl:ENSG00000105700(gene)|refseq:XP_016882770.1|refseq:XP_011526574.1|refseq:XP_011526575.1|refseq:XP_006722946.1|entrezgene/locuslink:79036(identity)	-	crc64:A5409FAF1594854C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	rogid:5BoR6AN0Ywb1eI04Rw4chmlWVI09606	intact-crc:14E273C15AA45BCD|rigid:/PHNZMGCVLir4/q0DlagUS4LjNQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32502	uniprotkb:Q9BQC3	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	intact:EBI-10237931|uniprotkb:O60623|uniprotkb:B4DNI8|uniprotkb:B2RDE3|uniprotkb:A8MVC9|ensembl:ENSP00000255108	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:dph2_human(display_long)|uniprotkb:Diphthamide biosynthesis protein 2(gene name synonym)|uniprotkb:Diphtheria toxin resistance protein 2(gene name synonym)|uniprotkb:DPH2(gene name)|psi-mi:DPH2(display_short)|uniprotkb:DPH2L2(gene name synonym)|uniprotkb:"S-adenosyl-L-methionine:L-histidine 3-amino-3-carboxypropyltransferase 2"(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11555523|imex:IM-24995-4417	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	refseq:NP_001306095.1|refseq:NP_001306098.1|refseq:NP_001034678.1|refseq:NP_001375.2|ensembl:ENSG00000132768(gene)|ensembl:ENST00000255108(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0017183"(peptidyl-diphthamide biosynthetic process from peptidyl-histidine)|go:"GO:0090560"("2-(3-amino-3-carboxypropyl)histidine synthase activity")|interpro:IPR010014(Diphthamide synthesis, DHP2)|interpro:IPR016435(Diphthamide synthesis, DHP1)|interpro:IPR042263|interpro:IPR042265|reactome:R-HSA-5358493|entrezgene/locuslink:1802(identity)	-	crc64:A5409FAF1594854C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	rogid:/Z9UhAa8qkHe3rPFS3OPfiJ4RFM9606	intact-crc:08EE4C895635BDB0|rigid:nG0On3X0/CoAisHrSzA34Kvk14s	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9BPX1	uniprotkb:P32502	intact:EBI-742664|uniprotkb:Q9UKU3|ensembl:ENSP00000263278	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:dhb14_human(display_long)|uniprotkb:DHRS10(gene name synonym)|uniprotkb:Dehydrogenase/reductase SDR family member 10(gene name synonym)|uniprotkb:17-beta-hydroxysteroid dehydrogenase DHRS10(gene name synonym)|uniprotkb:Retinal short-chain dehydrogenase/reductase retSDR3(gene name synonym)|uniprotkb:HSD17B14(gene name)|psi-mi:HSD17B14(display_short)|uniprotkb:SDR3(gene name synonym)|uniprotkb:SDR47C1(gene name synonym)|uniprotkb:Short chain dehydrogenase/reductase family 47C member 1(gene name synonym)|uniprotkb:UNQ502/PRO474(orf name)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11555514|imex:IM-24995-4416	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_057330.2|ensembl:ENSG00000087076(gene)|ensembl:ENST00000263278(transcript)|go:"GO:0004303"(estradiol 17-beta-dehydrogenase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006706"(steroid catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0044594"("17-beta-hydroxysteroid dehydrogenase (NAD+) activity")|go:"GO:0047045"("testosterone 17-beta-dehydrogenase (NADP+) activity")|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR020904|interpro:IPR036291|rcsb pdb:1YDE|rcsb pdb:5EN4|rcsb pdb:5HS6|rcsb pdb:5ICM|rcsb pdb:5ICS|rcsb pdb:5JS6|rcsb pdb:5JSF|rcsb pdb:5L7T|rcsb pdb:5L7W|rcsb pdb:5L7Y|rcsb pdb:5O42|rcsb pdb:5O43|rcsb pdb:5O6O|rcsb pdb:5O6X|rcsb pdb:5O6Z|rcsb pdb:5O72|rcsb pdb:5O7C|rcsb pdb:6EMM|rcsb pdb:6FFB|rcsb pdb:6G4L|rcsb pdb:6GBT|rcsb pdb:6GTB|rcsb pdb:6GTU|rcsb pdb:6H0M|rcsb pdb:6HNO|rcsb pdb:6QCK|rcsb pdb:6ZDE|rcsb pdb:6ZDI|reactome:R-HSA-193144|entrezgene/locuslink:51171(identity)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	-	-	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:/t03kHO/EWlqKNv7+TkWbTV9jpM9606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:C1B59EFFF1862FCF|rigid:vs25FILt8u/ffJMBLpyvWk9P8Cs	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32502	uniprotkb:Q96QF0-2	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	intact:EBI-747865|ensembl:ENSP00000247833	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:q96qf0-2(display_long)|uniprotkb:alpha1(isoform synonym)|uniprotkb:RAB3IP(gene name)|psi-mi:RAB3IP(display_short)|uniprotkb:Rabin-3(gene name synonym)|uniprotkb:SSX2-interacting protein(gene name synonym)|uniprotkb:RABIN8(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11555503|imex:IM-24995-4415	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	intact:EBI-747844(rab3i_human)|ensembl:ENSG00000127328(gene)|ensembl:ENST00000247833(transcript)|uniprotkb:Q96QF0-2(isoform-parent)|entrezgene/locuslink:117177(identity)	-	crc64:A5409FAF1594854C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	rogid:Vpmox/vANEwz2l+XaBdJslXrwyo9606	intact-crc:461BC0B8609F0DCF|rigid:RCBuD0oAg2xoF8AhY+F76pm7vTg	false	-	sufficient binding region:207-460	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32502	uniprotkb:Q96HR9	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	intact:EBI-750345|uniprotkb:Q96LM0|uniprotkb:B2RE01|uniprotkb:A0A1L5BXV3|uniprotkb:D6W5Z0|ensembl:ENSP00000378861	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:reep6_human(display_long)|uniprotkb:Polyposis locus protein 1-like 1(gene name synonym)|uniprotkb:REEP6(gene name)|psi-mi:REEP6(display_short)|uniprotkb:C19orf32(gene name synonym)|uniprotkb:DP1L1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11555494|imex:IM-24995-4414	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	refseq:NP_612402.1|refseq:NP_001316485.1|ensembl:ENSG00000115255(gene)|ensembl:ENST00000395479(transcript)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030665"(clathrin-coated vesicle membrane)|go:"GO:0032386"(regulation of intracellular transport)|go:"GO:0050908"(detection of light stimulus involved in visual perception)|interpro:IPR004345(TB2/DP1 and HVA22 related protein)|mint:Q96HR9|reactome:R-HSA-381753|go:"GO:0005634"(nucleus)|entrezgene/locuslink:92840(identity)	-	crc64:A5409FAF1594854C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2017/05/05	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	rogid:pB8AjjNTpmaaLJ8j7MCBM45UAHE9606	intact-crc:EF101B2493C72149|rigid:6hotnndLX78u2i77ARKqwuySncI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32502	uniprotkb:Q96HD9	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	intact:EBI-3916242|ensembl:ENSP00000255082	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:acy3_human(display_long)|uniprotkb:ACY3(gene name)|psi-mi:ACY3(display_short)|uniprotkb:Aspartoacylase-2(gene name synonym)|uniprotkb:ASPA2(gene name synonym)|uniprotkb:Acylase III(gene name synonym)|uniprotkb:Aminoacylase-3(gene name synonym)|uniprotkb:Hepatitis C virus core-binding protein 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11555485|imex:IM-24995-4413	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	refseq:NP_542389.1|ensembl:ENSG00000132744(gene)|ensembl:ENST00000255082(transcript)|go:"GO:0004046"(aminoacylase activity)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016788"(hydrolase activity, acting on ester bonds)|go:"GO:0016811"("hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides")|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR007036(Succinylglutamate desuccinylase/aspartoacylase)|interpro:IPR016708(Aspartoacylase)|mint:Q96HD9|reactome:R-HSA-5423646|go:"GO:0005829"(cytosol)|entrezgene/locuslink:91703(identity)	-	crc64:A5409FAF1594854C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	rogid:Zjs7m7GTDeoVuV1/ggtGOu1LRhM9606	intact-crc:BAE165A5F95DC246|rigid:Lbvd1J6/Qa1iLlH2qOS4/t3acXI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32502	uniprotkb:Q96HA8	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	intact:EBI-741158|uniprotkb:B4DE68|uniprotkb:Q9NW95|ensembl:ENSP00000287387	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:ntaq1_human(display_long)|uniprotkb:NTAQ1(gene name)|psi-mi:NTAQ1(display_short)|uniprotkb:C8orf32(gene name synonym)|uniprotkb:Protein NH2-terminal glutamine deamidase(gene name synonym)|uniprotkb:WDYHV motif-containing protein 1(gene name synonym)|uniprotkb:WDYHV1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11555476|imex:IM-24995-4412	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	refseq:NP_060494.1|refseq:NP_001269953.1|ensembl:ENSG00000156795(gene)|ensembl:ENST00000287387(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0008418"(protein-N-terminal asparagine amidohydrolase activity)|interpro:IPR023128|interpro:IPR037132|interpro:IPR039733|mint:Q96HA8|rcsb pdb:3C9Q|rcsb pdb:4W79|rcsb pdb:6KGJ|go:"GO:0070773"(protein-N-terminal glutamine amidohydrolase activity)|entrezgene/locuslink:55093(identity)	-	crc64:A5409FAF1594854C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	rogid:RKX6ww+Z/Zw6bmOXa0r8C0mxlvc9606	intact-crc:0A99C7C395564981|rigid:xjYCO1ebvGyeUhWxDtdeHBql7yk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32502	uniprotkb:Q9UHX1-5	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	intact:EBI-11526420|ensembl:ENSP00000395417|ensembl:ENSP00000478209	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:q9uhx1-5(display_long)|uniprotkb:PUF60(gene name)|psi-mi:PUF60(display_short)|uniprotkb:"60 kDa poly(U)-binding-splicing factor"(gene name synonym)|uniprotkb:FIR(gene name synonym)|uniprotkb:FUSE-binding protein-interacting repressor(gene name synonym)|uniprotkb:ROBPI(gene name synonym)|uniprotkb:Ro-binding protein 1(gene name synonym)|uniprotkb:SIAHBP1(gene name synonym)|uniprotkb:Siah-binding protein 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11555649|imex:IM-24995-4431	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	intact:EBI-1053259(isoform-parent)|ensembl:ENSG00000179950(gene)|ensembl:ENSG00000274081(gene)|ensembl:ENST00000456095(transcript)|ensembl:ENST00000620953(transcript)|entrezgene/locuslink:22827(identity)	-	crc64:A5409FAF1594854C	isoform-comment:"Contains a glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) at position 14."	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	rogid:PSbIU++DIL6ysF0ccd3ZHzeJ5rs9606	intact-crc:70E56D3DA273A275|rigid:PzoP+QJrcfD3B9lJsjj4mbQViMs	false	-	sufficient binding region:15-530	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UDV6	uniprotkb:P32502	intact:EBI-1640204|uniprotkb:Q13396|uniprotkb:Q8N664|uniprotkb:B2RCF4|ensembl:ENSP00000338572	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:zn212_human(display_long)|uniprotkb:ZNF212(gene name)|psi-mi:ZNF212(display_short)|uniprotkb:ZNFC150(gene name synonym)|uniprotkb:Zinc finger protein C2H2-150(gene name synonym)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11555640|imex:IM-24995-4430	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_036388.2|ensembl:ENSG00000170260(gene)|ensembl:ENST00000335870(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR022137|interpro:IPR036051|interpro:IPR036236|mint:Q9UDV6|reactome:R-HSA-212436|entrezgene/locuslink:7988(identity)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	-	-	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:jZtScr5t/MR83+d1tdA9OiP4JCA9606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:93209209657E540F|rigid:hz8jvORgxHnLSOF79Y5sMHeFAbc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32502	uniprotkb:Q9P286	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	intact:EBI-741896|ensembl:ENSP00000322957|ensembl:ENSP00000367679|ensembl:ENSP00000367686|intact:EBI-1051061|uniprotkb:A8K5T6|uniprotkb:D3DW14|uniprotkb:Q5W115|uniprotkb:Q8TB93|uniprotkb:Q9BX09|uniprotkb:Q9ULF6	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:pak5_human(display_long)|uniprotkb:PAK5(gene name)|psi-mi:PAK5(display_short)|uniprotkb:KIAA1264(gene name synonym)|uniprotkb:PAK7(gene name synonym)|uniprotkb:p21-activated kinase 5(gene name synonym)|uniprotkb:p21-activated kinase 7(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11555631|imex:IM-24995-4429	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	ensembl:ENSG00000101349(gene)|go:"GO:0045202"(synapse)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR028754|interpro:IPR033923|interpro:IPR036936|rcsb pdb:2F57|reactome:R-HSA-428540|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013405|reactome:R-HSA-9013407|go:"GO:0043408"(regulation of MAPK cascade)|ensembl:ENST00000353224(transcript)|ensembl:ENST00000378423(transcript)|ensembl:ENST00000378429(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007165"(signal transduction)|go:"GO:0007612"(learning)|go:"GO:0007613"(memory)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016477"(cell migration)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0035556"(intracellular signal transduction)|refseq:NP_065074.1|refseq:NP_817127.1|refseq:XP_016883449.1|refseq:XP_016883450.1|refseq:XP_016883451.1|refseq:XP_016883452.1|refseq:XP_016883453.1|refseq:XP_016883454.1|entrezgene/locuslink:57144(identity)	-	crc64:A5409FAF1594854C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2017/06/28	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	rogid:xxNDwmHn4jv8toBmviGjFwBU32E9606	intact-crc:4B7B84FA76D34FCC|rigid:b6e7eWLgobYY9K2Dq57PbP/v+1I	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9NWS6	uniprotkb:P32502	intact:EBI-8638992|uniprotkb:B4DY02|ensembl:ENSP00000216214|ensembl:ENSP00000395892|intact:MINT-8162875|uniprotkb:Q5TII5|uniprotkb:B3KWG4|uniprotkb:Q96CY3	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:f118a_human(display_long)|uniprotkb:FAM118A(gene name)|psi-mi:FAM118A(display_short)|uniprotkb:C22orf8(gene name synonym)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11555622|imex:IM-24995-4428	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000100376(gene)|ensembl:ENST00000216214(transcript)|ensembl:ENST00000441876(transcript)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|interpro:IPR033353|interpro:IPR038916|interpro:IPR039444|refseq:NP_060381.2|refseq:NP_001098065.1|entrezgene/locuslink:55007(identity)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	-	comment:mint	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:zZMOyeZwAeoDNLBQ9EKYRw4+0BM9606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:F0C957E03CB91BFA|rigid:r/x3t0aXwgqnxLaZbMM7TomZnds	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9NVV9	uniprotkb:P32502	intact:EBI-741515|uniprotkb:Q53FQ1|uniprotkb:Q6IA99|ensembl:ENSP00000254250|uniprotkb:A6NCB6|uniprotkb:D3DSY5|uniprotkb:H9KV49	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:thap1_human(display_long)|uniprotkb:THAP1(gene name)|psi-mi:THAP1(display_short)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11555613|imex:IM-24995-4427	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060575.1|ensembl:ENSG00000131931(gene)|ensembl:ENST00000254250(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001650"(fibrillar center)|go:"GO:0001935"(endothelial cell proliferation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007049"(cell cycle)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016605"(PML body)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR006612(Zinc finger, C2CH-type)|interpro:IPR026516|interpro:IPR038441|mint:Q9NVV9|rcsb pdb:2JTG|rcsb pdb:2KO0|rcsb pdb:2L1G|refseq:NP_945354.1|entrezgene/locuslink:55145(identity)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	-	-	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:/KO90pu5tBnIVq9SMx1JYPXFCEQ9606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:07D1DAD0A1404A19|rigid:WfQwtYrbxl994hjGKdwyREUxCyI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32502	uniprotkb:Q9NTM9	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	intact:EBI-714918|uniprotkb:Q5TCZ8|uniprotkb:Q9Y321|ensembl:ENSP00000359507	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:cutc_human(display_long)|uniprotkb:CUTC(gene name)|psi-mi:CUTC(display_short)|uniprotkb:CGI-32(orf name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11555604|imex:IM-24995-4426	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	ensembl:ENSG00000119929(gene)|ensembl:ENST00000370476(transcript)|go:"GO:0005507"(copper ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006825"(copper ion transport)|go:"GO:0051262"(protein tetramerization)|go:"GO:0055070"(copper ion homeostasis)|interpro:IPR005627(CutC)|interpro:IPR023648|interpro:IPR036822|mint:Q9NTM9|refseq:NP_057044.2|reactome:R-HSA-936837|rcsb pdb:3IWP|entrezgene/locuslink:51076(identity)	-	crc64:A5409FAF1594854C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	rogid:MkxQTQ5IGq+/IZzPy3wSurdtB6w9606	intact-crc:DF6428BD6C3E457B|rigid:QuTE3NJKYsTVaEHhlnQxe8Ufvpc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9NSC5	uniprotkb:P32502	intact:EBI-748420|uniprotkb:O14580|uniprotkb:O95350|uniprotkb:Q9NSB9|uniprotkb:Q9NSC0|intact:EBI-2557809|uniprotkb:E9PCW9|uniprotkb:Q9NSC1|intact:EBI-28972925|ensembl:ENSP00000376162|ensembl:ENSP00000439937|ensembl:ENSP00000446026|intact:EBI-10175777|uniprotkb:B2RA10	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:home3_human(display_long)|uniprotkb:HOMER3(gene name)|psi-mi:HOMER3(display_short)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11555595|imex:IM-24995-4425	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000221222|ensembl:ENSP00000221222|ensembl:ENSP00000376162|ensembl:ENST00000433218|ensembl:ENSP00000396154|ensembl:ENSP00000439937|ensembl:ENSP00000446026|ensembl:ENST00000594439|ensembl:ENSP00000471835|refseq:XP_006723006.1|refseq:XP_006723007.1|refseq:NP_001139193.1|refseq:NP_001139194.1|refseq:NP_004829.3|refseq:NP_001139196.1|ensembl:ENSG00000051128(gene)|ensembl:ENST00000392351(transcript)|ensembl:ENST00000539827(transcript)|ensembl:ENST00000542541(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006605"(protein targeting)|go:"GO:0007216"(G protein-coupled glutamate receptor signaling pathway)|go:"GO:0014069"(postsynaptic density)|go:"GO:0030425"(dendrite)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0035256"(G protein-coupled glutamate receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|go:"GO:2001256"(regulation of store-operated calcium entry)|interpro:IPR000697(EVH1)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR044100|mint:Q9NSC5|rcsb pdb:2P8V|rcsb pdb:3CVF|reactome:R-HSA-6794361|entrezgene/locuslink:9454(identity)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	-	-	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:U1y/y52nnf7zQUCNQlqk7JDgXi49606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:1BF4E2CA1CE7F23A|rigid:nQ/5cQZN/Z9bvMLr5D5+hLXF3n0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32502	uniprotkb:Q9NRY6	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	intact:EBI-750734|uniprotkb:Q567U0|uniprotkb:Q8NBW6|uniprotkb:Q96F13|uniprotkb:A8K252|ensembl:ENSP00000316021|ensembl:ENSP00000459019|ensembl:ENSP00000459419|ensembl:ENSP00000491350|ensembl:ENSP00000491393|ensembl:ENSP00000492026|ensembl:ENSP00000492083|ensembl:ENSP00000483743	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:pls3_human(display_long)|uniprotkb:"Ca(2+)-dependent phospholipid scramblase 3"(gene name synonym)|uniprotkb:PLSCR3(gene name)|psi-mi:PLSCR3(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11555586|imex:IM-24995-4424	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	refseq:NP_001188505.1|refseq:NP_065093.2|ensembl:ENSG00000187838(gene)|ensembl:ENSG00000284009(gene)|ensembl:ENST00000324822(transcript)|ensembl:ENST00000574401(transcript)|ensembl:ENST00000576201(transcript)|ensembl:ENST00000619711(transcript)|ensembl:ENST00000639780(transcript)|ensembl:ENST00000639874(transcript)|ensembl:ENST00000640053(transcript)|ensembl:ENST00000640375(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017121"(plasma membrane phospholipid scrambling)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0017128"(phospholipid scramblase activity)|go:"GO:0032049"(cardiolipin biosynthetic process)|go:"GO:0032791"(lead ion binding)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043621"(protein self-association)|go:"GO:0045340"(mercury ion binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0090199"(regulation of release of cytochrome c from mitochondria)|interpro:IPR005552(Scramblase)|entrezgene/locuslink:57048(identity)	-	crc64:A5409FAF1594854C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	rogid:JKzacFCwrCQpcI3EJsLvpAbLFCA9606	intact-crc:24C49CBEF3865722|rigid:J7CqgW3akkZCt3ZZ9/kD37ajjBI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9NRG1	uniprotkb:P32502	intact:EBI-739759|uniprotkb:Q53HA7|uniprotkb:Q59EL9|uniprotkb:Q5VV18|uniprotkb:Q5VV20|uniprotkb:B7Z1Z3|ensembl:ENSP00000318602	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:prdc1_human(display_long)|uniprotkb:PRTFDC1(gene name)|psi-mi:PRTFDC1(display_short)|uniprotkb:HHGP(gene name synonym)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11555577|imex:IM-24995-4423	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001269715.1|refseq:NP_064585.1|ensembl:ENSG00000099256(gene)|ensembl:ENST00000320152(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0006166"(purine ribonucleoside salvage)|go:"GO:0042803"(protein homodimerization activity)|interpro:IPR000836(Phosphoribosyltransferase)|interpro:IPR005904(Hypoxanthine phosphoribosyl transferase)|interpro:IPR029057|rcsb pdb:2JBH|entrezgene/locuslink:56952(identity)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	-	-	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:grTZnSalFILRSeeZBjM1mTtF0xo9606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:4A80538828B92939|rigid:zxrZ2roKd1hs5E5IEnuM1CbHXBk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32502	uniprotkb:Q9Y3Q8	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	intact:EBI-739485|uniprotkb:A8MWR6|ensembl:ENSP00000300181|uniprotkb:A4D2C3|uniprotkb:D6W5V9	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:t22d4_human(display_long)|uniprotkb:TSC22D4(gene name)|psi-mi:TSC22D4(display_short)|uniprotkb:TILZ2(gene name synonym)|uniprotkb:TSC22-related-inducible leucine zipper protein 2(gene name synonym)|uniprotkb:Tsc-22-like protein THG-1(gene name synonym)|uniprotkb:THG1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11555750|imex:IM-24995-4441	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	ensembl:ENSG00000166925(gene)|ensembl:ENST00000300181(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006970"(response to osmotic stress)|interpro:IPR000580(TSC-22 / Dip / Bun)|interpro:IPR042553|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|refseq:NP_112197.1|refseq:NP_001289972.1|entrezgene/locuslink:81628(identity)	-	crc64:A5409FAF1594854C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	rogid:eL12cHY76zEPOXzT1HFKPSckS8Y9606	intact-crc:7DE220A95EDD550D|rigid:Di+XqheOggbNvebETiEmKrLRyVg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32502	uniprotkb:Q9Y2D8	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	intact:EBI-2212028|uniprotkb:B4DFE3|uniprotkb:J3KR02|uniprotkb:A8K8W0|uniprotkb:D3DT13|uniprotkb:Q6P2P8|uniprotkb:Q6ULS1|uniprotkb:Q7L168|uniprotkb:Q9UIX0|intact:EBI-10964529|ensembl:ENSP00000340279	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:adip_human(display_long)|uniprotkb:SSX2IP(gene name)|psi-mi:SSX2IP(display_short)|uniprotkb:KIAA0923(gene name synonym)|uniprotkb:Afadin DIL domain-interacting protein(gene name synonym)|uniprotkb:SSX2-interacting protein(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11555741|imex:IM-24995-4440	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	refseq:XP_011538912.1|refseq:NP_001159765.1|refseq:NP_001159766.1|refseq:NP_001159767.1|refseq:NP_001159889.1|refseq:NP_054740.3|refseq:XP_005270484.1|refseq:XP_005270485.1|refseq:XP_006710394.1|refseq:XP_016855723.1|ensembl:ENSG00000117155(gene)|ensembl:ENST00000342203(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005912"(adherens junction)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031252"(cell leading edge)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0035735"(intraciliary transport involved in cilium assembly)|go:"GO:0036064"(ciliary basal body)|go:"GO:0060271"(cilium assembly)|go:"GO:2000145"(regulation of cell motility)|interpro:IPR021622|mint:Q9Y2D8|entrezgene/locuslink:117178(identity)	-	crc64:A5409FAF1594854C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	rogid:E0VeMRF9SrpQKSJFP01XEbMjeF89606	intact-crc:423B63CB4D299B61|rigid:RUc60KIbnAdYEr1IMFPesdm94Xs	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32502	uniprotkb:Q9UPY8	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	intact:EBI-726739|uniprotkb:O00265|uniprotkb:Q6FI15|uniprotkb:Q9BZP7|uniprotkb:Q9BZP8|uniprotkb:B7WPK5|uniprotkb:Q6FHB0|ensembl:ENSP00000233121	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:mare3_human(display_long)|uniprotkb:End-binding protein 3(gene name synonym)|uniprotkb:EB1 protein family member 3(gene name synonym)|uniprotkb:RP3(gene name synonym)|uniprotkb:MAPRE3(gene name)|psi-mi:MAPRE3(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11555732|imex:IM-24995-4439	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	refseq:NP_036458.2|refseq:XP_016859086.1|refseq:NP_001289979.1|refseq:XP_006712030.1|refseq:XP_011531002.1|dip:DIP-56069N|ensembl:ENSG00000084764(gene)|ensembl:ENST00000233121(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0008017"(microtubule binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030496"(midbody)|go:"GO:0031110"(regulation of microtubule polymerization or depolymerization)|go:"GO:0031113"(regulation of microtubule polymerization)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0042802"(identical protein binding)|go:"GO:0045737"(positive regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051233"(spindle midzone)|go:"GO:0051301"(cell division)|go:"GO:1903033"(positive regulation of microtubule plus-end binding)|go:"GO:1904825"(protein localization to microtubule plus-end)|go:"GO:1905721"(mitotic spindle astral microtubule end)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR004953(EB1, C-terminal)|interpro:IPR027328|interpro:IPR027738|interpro:IPR036133|interpro:IPR036872|mint:Q9UPY8|rcsb pdb:1WYO|rcsb pdb:3CO1|rcsb pdb:3JAK|rcsb pdb:3JAL|rcsb pdb:3JAR|rcsb pdb:3TQ7|entrezgene/locuslink:22924(identity)	-	crc64:A5409FAF1594854C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	rogid:LHuufxyNrygS3iFW5mmg13R43NE9606	intact-crc:EED97733E23167F3|rigid:pcUI+ZAYoWEoUxXaEdL9Ti4WkEA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UNE7	uniprotkb:P32502	intact:EBI-357085|uniprotkb:O60526|uniprotkb:Q969U2|uniprotkb:Q9HBT1|uniprotkb:A2IDB9|ensembl:ENSP00000219548	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:chip_human(display_long)|uniprotkb:CHIP(gene name synonym)|uniprotkb:STUB1(gene name)|psi-mi:STUB1(display_short)|uniprotkb:PP1131(orf name)|uniprotkb:Carboxy terminus of Hsp70-interacting protein(gene name synonym)|uniprotkb:STIP1 homology and U box-containing protein 1(gene name synonym)|uniprotkb:CLL-associated antigen KW-8(gene name synonym)|uniprotkb:Antigen NY-CO-7(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase CHIP(gene name synonym)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11555723|imex:IM-24995-4438	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-29752N|refseq:NP_005852.2|refseq:NP_001280126.1|ensembl:ENSG00000103266(gene)|ensembl:ENST00000219548(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0002931"(response to ischemia)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030911"(TPR domain binding)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031371"(ubiquitin conjugating enzyme complex)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031943"(regulation of glucocorticoid metabolic process)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|go:"GO:0034605"(cellular response to heat)|go:"GO:0038128"(ERBB2 signaling pathway)|go:"GO:0042405"(nuclear inclusion body)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0046332"(SMAD binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0051604"(protein maturation)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0030579"(ubiquitin-dependent SMAD protein catabolic process)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061684"(chaperone-mediated autophagy)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0071218"(cellular response to misfolded protein)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0090035"(positive regulation of chaperone-mediated protein complex assembly)|go:"GO:0101031"(chaperone complex)|interpro:IPR003613(U box)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019734|interpro:IPR041312|mint:Q9UNE7|rcsb pdb:4KBQ|rcsb pdb:6EFK|rcsb pdb:6NSV|reactome:R-HSA-2173788|reactome:R-HSA-5213460|reactome:R-HSA-5675482|reactome:R-HSA-8863795|reactome:R-HSA-8939902|reactome:R-HSA-8948751|reactome:R-HSA-983168|entrezgene/locuslink:10273(identity)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	-	-	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:h4QyIM0TptgkQppPUgiKn68XjP49606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:F803F9CC9B8BE1D9|rigid:zTTDiLY+4UF0EULVlTU2BY5Jh4s	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32502	uniprotkb:Q9UJX2	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	intact:EBI-396137|uniprotkb:O75433|uniprotkb:Q9BS73|uniprotkb:B4E3A2|uniprotkb:B7WP05|uniprotkb:Q53FN2|uniprotkb:A8K6E5|uniprotkb:D3DQB7|ensembl:ENSP00000378350	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:cdc23_human(display_long)|uniprotkb:CDC23(gene name)|psi-mi:CDC23(display_short)|uniprotkb:ANAPC8(gene name synonym)|uniprotkb:Anaphase-promoting complex subunit 8(gene name synonym)|uniprotkb:Cyclosome subunit 8(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11555712|imex:IM-24995-4437	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	refseq:NP_004652.2|dip:DIP-32959N|ensembl:ENSG00000094880(gene)|ensembl:ENST00000394886(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0007091"(metaphase/anaphase transition of mitotic cell cycle)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030071"(regulation of mitotic metaphase/anaphase transition)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0051301"(cell division)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR007192(Cdc23)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|mint:Q9UJX2|rcsb pdb:4UI9|rcsb pdb:5A31|rcsb pdb:5G04|rcsb pdb:5G05|rcsb pdb:5KHR|rcsb pdb:5KHU|rcsb pdb:5L9T|rcsb pdb:5L9U|rcsb pdb:5LCW|rcsb pdb:6Q6G|rcsb pdb:6Q6H|rcsb pdb:6TLJ|rcsb pdb:6TM5|rcsb pdb:6TNT|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-9687136|reactome:R-HSA-983168|entrezgene/locuslink:8697(identity)	-	crc64:A5409FAF1594854C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	rogid:uTZL2UHzZHLoKnio/1LcuSzZpW09606	intact-crc:23A48731D30CF31A|rigid:oByXm7mip5OSH18LrnwpeWvZn+U	false	-	sufficient binding region:7-597	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UJV3-2	uniprotkb:P32502	intact:EBI-10172526|ensembl:ENSP00000413976	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:q9ujv3-2(display_long)|uniprotkb:RING-type E3 ubiquitin transferase MID2(gene name synonym)|uniprotkb:FXY2(gene name synonym)|uniprotkb:Midin-2(gene name synonym)|uniprotkb:Midline defect 2(gene name synonym)|uniprotkb:Midline-2(gene name synonym)|uniprotkb:RING finger protein 60(gene name synonym)|uniprotkb:RNF60(gene name synonym)|uniprotkb:TRIM1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 1(gene name synonym)|uniprotkb:MID2(gene name)|psi-mi:MID2(display_short)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11555701|imex:IM-24995-4436	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-751983(isoform-parent)|uniprotkb:Q9UJV3-2(isoform-parent)|ensembl:ENSG00000080561(gene)|ensembl:ENST00000443968(transcript)|entrezgene/locuslink:11043(identity)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	-	-	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:/FJ+V2H7SaWon7caUWkEkmHFVxQ9606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:F3CADD6874D47BD5|rigid:gLKZX2c9WnbLhrFzr0iSTW6taIU	false	sufficient binding region:21-705	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32502	uniprotkb:Q9UJC3	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	intact:EBI-746704|uniprotkb:O60561|uniprotkb:Q5TG44|uniprotkb:A8MU44|uniprotkb:B4DX15|uniprotkb:A8K8E9|intact:EBI-10969618|ensembl:ENSP00000360252	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:hook1_human(display_long)|uniprotkb:HOOK1(gene name)|psi-mi:HOOK1(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11555692|imex:IM-24995-4435	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	refseq:NP_056972.1|ensembl:ENSG00000134709(gene)|ensembl:ENST00000371208(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0007030"(Golgi organization)|go:"GO:0007032"(endosome organization)|go:"GO:0007040"(lysosome organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0015031"(protein transport)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0051959"(dynein light intermediate chain binding)|go:"GO:0070695"(FHF complex)|go:"GO:1905198"(manchette assembly)|go:"GO:1905719"(protein localization to perinuclear region of cytoplasm)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR008636(HOOK)|interpro:IPR036872|interpro:IPR043936|mint:Q9UJC3|entrezgene/locuslink:51361(identity)	-	crc64:A5409FAF1594854C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	rogid:QOcYbuKfnNIlNKzos5v+0+A2h3I9606	intact-crc:24F1BEE9EF7C48A7|rigid:7kYUYjTM18DA+gT+GyTew1DPD6Y	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UJ70-2	uniprotkb:P32502	intact:EBI-11526455|ensembl:ENSP00000389087|ensembl:ENSP00000477639	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:q9uj70-2(display_long)|uniprotkb:GlcNAc kinase(gene name synonym)|uniprotkb:NAGK(gene name)|psi-mi:NAGK(display_short)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11555680|imex:IM-24995-4434	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-372578(isoform-parent)|ensembl:ENSG00000124357(gene)|ensembl:ENST00000455662(transcript)|ensembl:ENST00000613852(transcript)|uniprotkb:Q9UJ70-2(isoform-parent)|entrezgene/locuslink:55577(identity)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	-	-	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:zoy4C+HK341UnmDRUlMuJucczr89606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:25FED1E4EB2FD571|rigid:n0pwos02ttUq0m9zwT4vZ4lEN7E	false	sufficient binding region:47-390	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UI14	uniprotkb:P32502	intact:EBI-712367|ensembl:ENSP00000222008|uniprotkb:Q7Z4Y2|uniprotkb:Q9Y3R1	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:praf1_human(display_long)|uniprotkb:PRA1 family protein 1(gene name synonym)|uniprotkb:RABAC1(gene name)|psi-mi:RABAC1(display_short)|uniprotkb:PRA1(gene name synonym)|uniprotkb:PRAF1(gene name synonym)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11555671|imex:IM-24995-4433	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006414.2|ensembl:ENSG00000105404(gene)|ensembl:ENST00000222008(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0070064"(proline-rich region binding)|interpro:IPR004895(Prenylated rab acceptor PRA1)|mint:Q9UI14|entrezgene/locuslink:10567(identity)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	-	-	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:WS2rUY7yXRbR7pqWgfUCbnEiDbg9606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:1966C4387140F4D4|rigid:1nv/6BMInnXsSwk8QbyMG8XZv/s	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32502	uniprotkb:Q9UHX1-6	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	intact:EBI-11085298|ensembl:ENSP00000431960	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:q9uhx1-6(display_long)|uniprotkb:PUF60(gene name)|psi-mi:PUF60(display_short)|uniprotkb:"60 kDa poly(U)-binding-splicing factor"(gene name synonym)|uniprotkb:FIR(gene name synonym)|uniprotkb:FUSE-binding protein-interacting repressor(gene name synonym)|uniprotkb:ROBPI(gene name synonym)|uniprotkb:Ro-binding protein 1(gene name synonym)|uniprotkb:SIAHBP1(gene name synonym)|uniprotkb:Siah-binding protein 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11555660|imex:IM-24995-4432	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	ensembl:ENSG00000179950(gene)|ensembl:ENST00000527197(transcript)|intact:EBI-1053259(isoform-parent)|uniprotkb:Q9UHX1-6(isoform-parent)|entrezgene/locuslink:22827(identity)	-	crc64:A5409FAF1594854C	isoform-comment:"Contains a glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) at position 14."	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	rogid:rSsTImwmpEAWMCxLzF5Y4zVdeFM9606	intact-crc:EFECFD1DD11F98BD|rigid:t73OVeVNVLQvgjkmczlo9d3vUIw	false	-	sufficient binding region:15-513	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32562	uniprotkb:Q7L5A3	intact:EBI-4440|ensemblfungi:YMR001C|uniprotkb:D6VZH5	intact:EBI-745689|uniprotkb:O60377|uniprotkb:Q9BQ60|uniprotkb:Q9HAI9|uniprotkb:Q9P1Y9|ensembl:ENSP00000319897|ensembl:ENSP00000367819|ensembl:ENSP00000367823|ensembl:ENSP00000474335|ensembl:ENSP00000474833|ensembl:ENSP00000475120|uniprotkb:D3DRN5|uniprotkb:B1AML4|uniprotkb:B1AML5	psi-mi:cdc5_yeast(display_long)|uniprotkb:CDC5(gene name)|psi-mi:CDC5(display_short)|uniprotkb:MSD2(gene name synonym)|uniprotkb:PKX2(gene name synonym)|uniprotkb:YMR001C(locus name)|uniprotkb:YM8270.03C(orf name)	psi-mi:f214b_human(display_long)|uniprotkb:FAM214B(gene name)|psi-mi:FAM214B(display_short)|uniprotkb:KIAA1539(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11555838|imex:IM-24995-4450	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YMR001C(gene)|ensemblfungi:YMR001C_mRNA(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0000922"(spindle pole)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0010458"(exit from mitosis)|go:"GO:0010696"(positive regulation of mitotic spindle pole body separation)|go:"GO:0019237"(centromeric DNA binding)|refseq:NP_013714.1|sgd:S000004603|reactome:R-SCE-6804115|reactome:R-SCE-156711|reactome:R-SCE-162658|reactome:R-SCE-2565942|dip:DIP-2321N|reactome:R-SCE-2500257|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0035025"(positive regulation of Rho protein signal transduction)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051301"(cell division)|go:"GO:0070194"(synaptonemal complex disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0110083"(positive regulation of protein localization to cell division site involved in mitotic actomyosin contractile ring assembly)|go:"GO:1902542"(regulation of protein localization to mitotic spindle pole body)|go:"GO:1903353"(regulation of nucleus organization)|go:"GO:1904750"(negative regulation of protein localization to nucleolus)|go:"GO:1905339"(positive regulation of cohesin unloading)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033695|interpro:IPR033701|interpro:IPR036947|rcsb pdb:6MF4|rcsb pdb:6MF5|rcsb pdb:6MF6|sgd:YMR001C(identity)	refseq:NP_079458.2|refseq:XP_011516339.1|refseq:XP_011516345.1|refseq:XP_011516346.1|ensembl:ENST00000603301(transcript)|ensembl:ENST00000605244(transcript)|go:"GO:0005634"(nucleus)|interpro:IPR025261|interpro:IPR033473|mint:Q7L5A3|ensembl:ENSG00000005238(gene)|ensembl:ENST00000322813(transcript)|ensembl:ENST00000378557(transcript)|ensembl:ENST00000378561(transcript)|ensembl:ENST00000488109(transcript)|refseq:NP_001304920.1|refseq:XP_005251645.1|refseq:XP_005251647.1|refseq:XP_005251648.1|refseq:XP_016870659.1|entrezgene/locuslink:80256(identity)	-	crc64:B5A25F1BBBEAA3DC	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:XXSkltYvBA9Zkh0Kr5s1znazUC0559292	rogid:M9Hjv238OhxmmyVQbKrX6JOYL7k9606	intact-crc:B2BDF0FB039BB589|rigid:6bX+YSG9XqF0QTwLWHdgCismuoA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32562	uniprotkb:Q13422-7	intact:EBI-4440|ensemblfungi:YMR001C|uniprotkb:D6VZH5	intact:EBI-11522367|ensembl:ENSP00000352123|ensembl:ENSP00000413025	psi-mi:cdc5_yeast(display_long)|uniprotkb:CDC5(gene name)|psi-mi:CDC5(display_short)|uniprotkb:MSD2(gene name synonym)|uniprotkb:PKX2(gene name synonym)|uniprotkb:YMR001C(locus name)|uniprotkb:YM8270.03C(orf name)	psi-mi:q13422-7(display_long)|uniprotkb:IKZF1(gene name)|psi-mi:IKZF1(display_short)|uniprotkb:IK1(gene name synonym)|uniprotkb:IKAROS(gene name synonym)|uniprotkb:Ikaros family zinc finger protein 1(gene name synonym)|uniprotkb:LYF1(gene name synonym)|uniprotkb:Lymphoid transcription factor LyF-1(gene name synonym)|uniprotkb:ZNFN1A1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11555829|imex:IM-24995-4449	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YMR001C(gene)|ensemblfungi:YMR001C_mRNA(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0000922"(spindle pole)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0010458"(exit from mitosis)|go:"GO:0010696"(positive regulation of mitotic spindle pole body separation)|go:"GO:0019237"(centromeric DNA binding)|refseq:NP_013714.1|sgd:S000004603|reactome:R-SCE-6804115|reactome:R-SCE-156711|reactome:R-SCE-162658|reactome:R-SCE-2565942|dip:DIP-2321N|reactome:R-SCE-2500257|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0035025"(positive regulation of Rho protein signal transduction)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051301"(cell division)|go:"GO:0070194"(synaptonemal complex disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0110083"(positive regulation of protein localization to cell division site involved in mitotic actomyosin contractile ring assembly)|go:"GO:1902542"(regulation of protein localization to mitotic spindle pole body)|go:"GO:1903353"(regulation of nucleus organization)|go:"GO:1904750"(negative regulation of protein localization to nucleolus)|go:"GO:1905339"(positive regulation of cohesin unloading)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033695|interpro:IPR033701|interpro:IPR036947|rcsb pdb:6MF4|rcsb pdb:6MF5|rcsb pdb:6MF6|sgd:YMR001C(identity)	intact:EBI-745305(isoform-parent)|ensembl:ENSG00000185811(gene)|ensembl:ENST00000359197(transcript)|ensembl:ENST00000439701(transcript)|uniprotkb:Q13422-7(isoform-parent)|entrezgene/locuslink:10320(identity)	-	crc64:B5A25F1BBBEAA3DC	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:XXSkltYvBA9Zkh0Kr5s1znazUC0559292	rogid:ou/ovXYoMneBNVp4pj38VxenfyY9606	intact-crc:FC74848463654471|rigid:HDP6+0UygbB4Z+9FmY++33zoPyc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32562	uniprotkb:P63279	intact:EBI-4440|ensemblfungi:YMR001C|uniprotkb:D6VZH5	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	psi-mi:cdc5_yeast(display_long)|uniprotkb:CDC5(gene name)|psi-mi:CDC5(display_short)|uniprotkb:MSD2(gene name synonym)|uniprotkb:PKX2(gene name synonym)|uniprotkb:YMR001C(locus name)|uniprotkb:YM8270.03C(orf name)	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11555820|imex:IM-24995-4448	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YMR001C(gene)|ensemblfungi:YMR001C_mRNA(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0000922"(spindle pole)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0010458"(exit from mitosis)|go:"GO:0010696"(positive regulation of mitotic spindle pole body separation)|go:"GO:0019237"(centromeric DNA binding)|refseq:NP_013714.1|sgd:S000004603|reactome:R-SCE-6804115|reactome:R-SCE-156711|reactome:R-SCE-162658|reactome:R-SCE-2565942|dip:DIP-2321N|reactome:R-SCE-2500257|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0035025"(positive regulation of Rho protein signal transduction)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051301"(cell division)|go:"GO:0070194"(synaptonemal complex disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0110083"(positive regulation of protein localization to cell division site involved in mitotic actomyosin contractile ring assembly)|go:"GO:1902542"(regulation of protein localization to mitotic spindle pole body)|go:"GO:1903353"(regulation of nucleus organization)|go:"GO:1904750"(negative regulation of protein localization to nucleolus)|go:"GO:1905339"(positive regulation of cohesin unloading)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033695|interpro:IPR033701|interpro:IPR036947|rcsb pdb:6MF4|rcsb pdb:6MF5|rcsb pdb:6MF6|sgd:YMR001C(identity)	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N|entrezgene/locuslink:7329(identity)	-	crc64:B5A25F1BBBEAA3DC	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:XXSkltYvBA9Zkh0Kr5s1znazUC0559292	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	intact-crc:7D665BD0D997F73A|rigid:ko/lk8jigrCH06sKQuyEbR2AXj4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P14859-6	uniprotkb:P32562	intact:EBI-11526590|ensembl:ENSP00000356840	intact:EBI-4440|ensemblfungi:YMR001C|uniprotkb:D6VZH5	psi-mi:p14859-6(display_long)|uniprotkb:NF-A1(gene name synonym)|uniprotkb:OCT1(gene name synonym)|uniprotkb:OTF1(gene name synonym)|uniprotkb:Octamer-binding protein 1(gene name synonym)|uniprotkb:Octamer-binding transcription factor 1(gene name synonym)|uniprotkb:POU2F1(gene name)|psi-mi:POU2F1(display_short)	psi-mi:cdc5_yeast(display_long)|uniprotkb:CDC5(gene name)|psi-mi:CDC5(display_short)|uniprotkb:MSD2(gene name synonym)|uniprotkb:PKX2(gene name synonym)|uniprotkb:YMR001C(locus name)|uniprotkb:YM8270.03C(orf name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11555809|imex:IM-24995-4447	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000143190(gene)|ensembl:ENST00000367866(transcript)|intact:EBI-624770(isoform-parent)|uniprotkb:P14859-6(isoform-parent)|entrezgene/locuslink:5451(identity)	ensemblfungi:YMR001C(gene)|ensemblfungi:YMR001C_mRNA(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0000922"(spindle pole)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0010458"(exit from mitosis)|go:"GO:0010696"(positive regulation of mitotic spindle pole body separation)|go:"GO:0019237"(centromeric DNA binding)|refseq:NP_013714.1|sgd:S000004603|reactome:R-SCE-6804115|reactome:R-SCE-156711|reactome:R-SCE-162658|reactome:R-SCE-2565942|dip:DIP-2321N|reactome:R-SCE-2500257|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0035025"(positive regulation of Rho protein signal transduction)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051301"(cell division)|go:"GO:0070194"(synaptonemal complex disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0110083"(positive regulation of protein localization to cell division site involved in mitotic actomyosin contractile ring assembly)|go:"GO:1902542"(regulation of protein localization to mitotic spindle pole body)|go:"GO:1903353"(regulation of nucleus organization)|go:"GO:1904750"(negative regulation of protein localization to nucleolus)|go:"GO:1905339"(positive regulation of cohesin unloading)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033695|interpro:IPR033701|interpro:IPR036947|rcsb pdb:6MF4|rcsb pdb:6MF5|rcsb pdb:6MF6|sgd:YMR001C(identity)	-	isoform-comment:No experimental confirmation available.	crc64:B5A25F1BBBEAA3DC	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:jKwhpG5wRMncTZjM6bNUCL0CPqQ9606	rogid:XXSkltYvBA9Zkh0Kr5s1znazUC0559292	intact-crc:7D49A3D9825623CC|rigid:pKDK+p9Bd/jFaUKhj9be5X4eW2g	false	sufficient binding region:24-766	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32529	uniprotkb:Q13422-7	intact:EBI-15756|uniprotkb:D6VWN4|ensemblfungi:YJR063W	intact:EBI-11522367|ensembl:ENSP00000352123|ensembl:ENSP00000413025	psi-mi:rpa12_yeast(display_long)|uniprotkb:RPA12(gene name)|psi-mi:RPA12(display_short)|uniprotkb:RRN4(gene name synonym)|uniprotkb:YJR063W(locus name)|uniprotkb:J1747(orf name)|uniprotkb:DNA-directed RNA polymerase I 13.7 kDa polypeptide(gene name synonym)|uniprotkb:A12(gene name synonym)|uniprotkb:A12.2(gene name synonym)	psi-mi:q13422-7(display_long)|uniprotkb:IKZF1(gene name)|psi-mi:IKZF1(display_short)|uniprotkb:IK1(gene name synonym)|uniprotkb:IKAROS(gene name synonym)|uniprotkb:Ikaros family zinc finger protein 1(gene name synonym)|uniprotkb:LYF1(gene name synonym)|uniprotkb:Lymphoid transcription factor LyF-1(gene name synonym)|uniprotkb:ZNFN1A1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11555800|imex:IM-24995-4446	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012597.1|sgd:S000003824|dip:DIP-236N|mint:P32529|ensemblfungi:YJR063W(gene)|ensemblfungi:YJR063W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001054"(RNA polymerase I activity)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006363"(termination of RNA polymerase I transcription)|go:"GO:0006379"(mRNA cleavage)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042790"(nucleolar large rRNA transcription by RNA polymerase I)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR001222(Zinc finger, TFIIS-type)|interpro:IPR001529(DNA-directed RNA polymerase, M/15 kDa subunit)|interpro:IPR012164(DNA-directed RNA polymerase, subunit C11/M/9)|interpro:IPR019761|interpro:IPR034004|rcsb pdb:4C2M|rcsb pdb:4C3H|rcsb pdb:4C3I|rcsb pdb:4C3J|rcsb pdb:4YM7|rcsb pdb:5G5L|rcsb pdb:5LMX|rcsb pdb:5M3F|rcsb pdb:5M3M|rcsb pdb:5M5W|rcsb pdb:5M5X|rcsb pdb:5M5Y|rcsb pdb:5M64|rcsb pdb:5N5Y|rcsb pdb:5N5Z|rcsb pdb:5N60|rcsb pdb:5N61|rcsb pdb:5OA1|rcsb pdb:5W5Y|rcsb pdb:5W64|rcsb pdb:5W65|rcsb pdb:5W66|rcsb pdb:6H67|rcsb pdb:6H68|rcsb pdb:6HKO|rcsb pdb:6HLQ|rcsb pdb:6HLR|rcsb pdb:6HLS|rcsb pdb:6RQH|rcsb pdb:6RQL|rcsb pdb:6RQT|rcsb pdb:6RRD|rcsb pdb:6RUI|rcsb pdb:6RUO|rcsb pdb:6RWE|rcsb pdb:6TPS|reactome:R-SCE-73762|reactome:R-SCE-73772|sgd:YJR063W(identity)	intact:EBI-745305(isoform-parent)|ensembl:ENSG00000185811(gene)|ensembl:ENST00000359197(transcript)|ensembl:ENST00000439701(transcript)|uniprotkb:Q13422-7(isoform-parent)|entrezgene/locuslink:10320(identity)	-	crc64:D79372070819987C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:B0Zmf643W8DtAQteaDk8PVvdqW4559292	rogid:ou/ovXYoMneBNVp4pj38VxenfyY9606	intact-crc:839CBAA5CBF2EAFF|rigid:OkVugayMDgkvP4sET1tDl42XLrc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32529	uniprotkb:Q08379	intact:EBI-15756|uniprotkb:D6VWN4|ensemblfungi:YJR063W	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	psi-mi:rpa12_yeast(display_long)|uniprotkb:RPA12(gene name)|psi-mi:RPA12(display_short)|uniprotkb:RRN4(gene name synonym)|uniprotkb:YJR063W(locus name)|uniprotkb:J1747(orf name)|uniprotkb:DNA-directed RNA polymerase I 13.7 kDa polypeptide(gene name synonym)|uniprotkb:A12(gene name synonym)|uniprotkb:A12.2(gene name synonym)	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11555789|imex:IM-24995-4445	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012597.1|sgd:S000003824|dip:DIP-236N|mint:P32529|ensemblfungi:YJR063W(gene)|ensemblfungi:YJR063W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001054"(RNA polymerase I activity)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006363"(termination of RNA polymerase I transcription)|go:"GO:0006379"(mRNA cleavage)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042790"(nucleolar large rRNA transcription by RNA polymerase I)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR001222(Zinc finger, TFIIS-type)|interpro:IPR001529(DNA-directed RNA polymerase, M/15 kDa subunit)|interpro:IPR012164(DNA-directed RNA polymerase, subunit C11/M/9)|interpro:IPR019761|interpro:IPR034004|rcsb pdb:4C2M|rcsb pdb:4C3H|rcsb pdb:4C3I|rcsb pdb:4C3J|rcsb pdb:4YM7|rcsb pdb:5G5L|rcsb pdb:5LMX|rcsb pdb:5M3F|rcsb pdb:5M3M|rcsb pdb:5M5W|rcsb pdb:5M5X|rcsb pdb:5M5Y|rcsb pdb:5M64|rcsb pdb:5N5Y|rcsb pdb:5N5Z|rcsb pdb:5N60|rcsb pdb:5N61|rcsb pdb:5OA1|rcsb pdb:5W5Y|rcsb pdb:5W64|rcsb pdb:5W65|rcsb pdb:5W66|rcsb pdb:6H67|rcsb pdb:6H68|rcsb pdb:6HKO|rcsb pdb:6HLQ|rcsb pdb:6HLR|rcsb pdb:6HLS|rcsb pdb:6RQH|rcsb pdb:6RQL|rcsb pdb:6RQT|rcsb pdb:6RRD|rcsb pdb:6RUI|rcsb pdb:6RUO|rcsb pdb:6RWE|rcsb pdb:6TPS|reactome:R-SCE-73762|reactome:R-SCE-73772|sgd:YJR063W(identity)	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N|entrezgene/locuslink:2801(identity)	-	crc64:D79372070819987C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2017/05/26	rogid:B0Zmf643W8DtAQteaDk8PVvdqW4559292	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	intact-crc:3B0209AA46E472CC|rigid:iRbmEMepCZ591rpMbFdcN5GsJBU	false	-	sufficient binding region:383-1002	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32505	uniprotkb:Q86SE5-3	intact:EBI-11770|ensemblfungi:YGL122C|uniprotkb:D6VU26	intact:EBI-11526555|ensembl:ENSP00000430128	psi-mi:nab2_yeast(display_long)|uniprotkb:YGL122C(locus name)|uniprotkb:NAB2(gene name)|psi-mi:NAB2(display_short)	psi-mi:q86se5-3(display_long)|uniprotkb:RALYL(gene name)|psi-mi:RALYL(display_short)|uniprotkb:HNRPCL3(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein C-like 3(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11555778|imex:IM-24995-4444	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YGL122C(gene)|ensemblfungi:YGL122C_mRNA(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0008097"(5S rRNA binding)|go:"GO:0008143"("poly(A) binding")|go:"GO:0008312"(7S RNA binding)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0033204"(ribonuclease P RNA binding)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0046872"(metal ion binding)|go:"GO:1900152"(negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|interpro:IPR021083|interpro:IPR040366|go:"GO:0045945"(positive regulation of transcription by RNA polymerase III)|interpro:IPR041044|interpro:IPR043094|rcsb pdb:2JPS|rcsb pdb:2LHN|rcsb pdb:2V75|rcsb pdb:3LCN|rcsb pdb:3ZJ1|rcsb pdb:3ZJ2|rcsb pdb:4JLQ|rcsb pdb:5L2L|refseq:NP_011393.3|sgd:S000003090|mint:P32505|dip:DIP-1331N|sgd:YGL122C(identity)	ensembl:ENSG00000184672(gene)|ensembl:ENST00000517638(transcript)|intact:EBI-741520(isoform-parent)|uniprotkb:Q86SE5-3(isoform-parent)|entrezgene/locuslink:138046(identity)	-	crc64:40335C3D4658DD91	isoform-comment:No experimental confirmation available.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:tNdhCVVTRYjqg7BES5wD2Gg4rjw559292	rogid:7Vx29NJ3c8JBc76fGQWhrrQ9Stg9606	intact-crc:AEDB47656E3A30B3|rigid:qh+Ucdp9I+wW4n5ydm5yk/WsF0c	false	-	sufficient binding region:14-304	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32505	uniprotkb:P38159	intact:EBI-11770|ensemblfungi:YGL122C|uniprotkb:D6VU26	intact:EBI-743526|ensembl:ENSP00000359645|uniprotkb:Q5JQ67|uniprotkb:Q969R3|uniprotkb:D3DWH0|uniprotkb:E9PG86|uniprotkb:Q8N8Y7|uniprotkb:B4E3U4	psi-mi:nab2_yeast(display_long)|uniprotkb:YGL122C(locus name)|uniprotkb:NAB2(gene name)|psi-mi:NAB2(display_short)	psi-mi:rbmx_human(display_long)|uniprotkb:Glycoprotein p43(gene name synonym)|uniprotkb:RBMX(gene name)|psi-mi:RBMX(display_short)|uniprotkb:HNRPG(gene name synonym)|uniprotkb:RBMXP1(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein G(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11555769|imex:IM-24995-4443	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YGL122C(gene)|ensemblfungi:YGL122C_mRNA(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0008097"(5S rRNA binding)|go:"GO:0008143"("poly(A) binding")|go:"GO:0008312"(7S RNA binding)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0033204"(ribonuclease P RNA binding)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0046872"(metal ion binding)|go:"GO:1900152"(negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|interpro:IPR021083|interpro:IPR040366|go:"GO:0045945"(positive regulation of transcription by RNA polymerase III)|interpro:IPR041044|interpro:IPR043094|rcsb pdb:2JPS|rcsb pdb:2LHN|rcsb pdb:2V75|rcsb pdb:3LCN|rcsb pdb:3ZJ1|rcsb pdb:3ZJ2|rcsb pdb:4JLQ|rcsb pdb:5L2L|refseq:NP_011393.3|sgd:S000003090|mint:P32505|dip:DIP-1331N|sgd:YGL122C(identity)	ensembl:ENSG00000147274(gene)|ensembl:ENST00000320676(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000791"(euchromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0044530"(supraspliceosomal complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0006509"(membrane protein ectodomain proteolysis)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012604(RBM1CTR)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|mint:P38159|rcsb pdb:2MB0|rcsb pdb:2MKS|reactome:R-HSA-72163|reactome:R-HSA-72203|reactome:R-HSA-9013418|reactome:R-HSA-9013422|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273|refseq:NP_002130.2|refseq:NP_001158275.1|dip:DIP-34447N|entrezgene/locuslink:27316(identity)	-	crc64:40335C3D4658DD91	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:tNdhCVVTRYjqg7BES5wD2Gg4rjw559292	rogid:ocCkdy9PxjeVLUQf0tMVCEhFfO89606	intact-crc:7A1F1C485791C468|rigid:OHmVTY27Tx1ptByqU/vkxddfBgc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32502	uniprotkb:Q9Y6D9	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	intact:EBI-742610|uniprotkb:B3KR41|uniprotkb:Q9UNH0|uniprotkb:Q13312|uniprotkb:Q75MI0|uniprotkb:Q86UM4|ensembl:ENSP00000265854|ensembl:ENSP00000382562|ensembl:ENSP00000385334	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:md1l1_human(display_long)|uniprotkb:Mitotic arrest deficient 1-like protein 1(gene name synonym)|uniprotkb:Mitotic checkpoint MAD1 protein homolog(gene name synonym)|uniprotkb:Tax-binding protein 181(gene name synonym)|uniprotkb:MAD1L1(gene name)|psi-mi:MAD1L1(display_short)|uniprotkb:MAD1(gene name synonym)|uniprotkb:TXBP181(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11555760|imex:IM-24995-4442	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	refseq:NP_001013858.1|refseq:NP_001013859.1|refseq:NP_003541.2|refseq:NP_001291452.1|refseq:NP_001291453.1|ensembl:ENSG00000002822(gene)|ensembl:ENST00000265854(transcript)|go:"GO:0090235"(regulation of metaphase plate congression)|go:"GO:1902426"(deactivation of mitotic spindle assembly checkpoint)|interpro:IPR008672(Mitotic checkpoint)|mint:Q9Y6D9|rcsb pdb:1GO4|rcsb pdb:4DZO|rcsb pdb:7B1F|rcsb pdb:7B1H|rcsb pdb:7B1J|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|ensembl:ENST00000399654(transcript)|ensembl:ENST00000406869(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043515"(kinetochore binding)|go:"GO:0044615"(nuclear pore nuclear basket)|go:"GO:0048538"(thymus development)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0072686"(mitotic spindle)|refseq:XP_005249934.1|dip:DIP-29654N|entrezgene/locuslink:8379(identity)	-	crc64:A5409FAF1594854C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	rogid:9CcqpZlN0IgqC939rIo7vNgOvLQ9606	intact-crc:63BEE27819D806C3|rigid:i1ztDpU8PgAzP0pVDv/71CBfv5k	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9NSC5	uniprotkb:P32571	intact:EBI-748420|uniprotkb:O14580|uniprotkb:O95350|uniprotkb:Q9NSB9|uniprotkb:Q9NSC0|intact:EBI-2557809|uniprotkb:E9PCW9|uniprotkb:Q9NSC1|intact:EBI-28972925|ensembl:ENSP00000376162|ensembl:ENSP00000439937|ensembl:ENSP00000446026|intact:EBI-10175777|uniprotkb:B2RA10	intact:EBI-19840|uniprotkb:D6VS55|ensemblfungi:YDR069C	psi-mi:home3_human(display_long)|uniprotkb:HOMER3(gene name)|psi-mi:HOMER3(display_short)	psi-mi:ubp4_yeast(display_long)|uniprotkb:DOA4(gene name)|psi-mi:DOA4(display_short)|uniprotkb:MUT4(gene name synonym)|uniprotkb:SSV7(gene name synonym)|uniprotkb:YDR069C(locus name)|uniprotkb:YD9609.23C(orf name)|uniprotkb:YD8554.02C(orf name)|uniprotkb:D4270(orf name)|uniprotkb:NPI2(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 4(gene name synonym)|uniprotkb:Deubiquitinating enzyme 4(gene name synonym)|uniprotkb:Vacuole biogenesis protein SSV7(gene name synonym)|uniprotkb:Ubiquitin thioesterase 4(gene name synonym)|uniprotkb:DOS1(gene name synonym)|uniprotkb:UBP4(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11555920|imex:IM-24995-4459	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000221222|ensembl:ENSP00000221222|ensembl:ENSP00000376162|ensembl:ENST00000433218|ensembl:ENSP00000396154|ensembl:ENSP00000439937|ensembl:ENSP00000446026|ensembl:ENST00000594439|ensembl:ENSP00000471835|refseq:XP_006723006.1|refseq:XP_006723007.1|refseq:NP_001139193.1|refseq:NP_001139194.1|refseq:NP_004829.3|refseq:NP_001139196.1|ensembl:ENSG00000051128(gene)|ensembl:ENST00000392351(transcript)|ensembl:ENST00000539827(transcript)|ensembl:ENST00000542541(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006605"(protein targeting)|go:"GO:0007216"(G protein-coupled glutamate receptor signaling pathway)|go:"GO:0014069"(postsynaptic density)|go:"GO:0030425"(dendrite)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0035256"(G protein-coupled glutamate receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|go:"GO:2001256"(regulation of store-operated calcium entry)|interpro:IPR000697(EVH1)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR044100|mint:Q9NSC5|rcsb pdb:2P8V|rcsb pdb:3CVF|reactome:R-HSA-6794361|entrezgene/locuslink:9454(identity)	sgd:S000002476|ensemblfungi:YDR069C(gene)|ensemblfungi:YDR069C_mRNA(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005739"(mitochondrion)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0010992"(ubiquitin recycling)|go:"GO:0010995"(free ubiquitin chain depolymerization)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0031902"(late endosome membrane)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0070676"(intralumenal vesicle formation)|go:"GO:1904669"(ATP export)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR001763(Rhodanese-like)|interpro:IPR018200|interpro:IPR028889|interpro:IPR036873|interpro:IPR038765|refseq:NP_010354.3|dip:DIP-5298N|mint:P32571|sgd:YDR069C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:U1y/y52nnf7zQUCNQlqk7JDgXi49606	rogid:UTBSWmpygyxo1ygxp/sQ8wgqnMo559292	intact-crc:2C2770B8F94CA3B9|rigid:9DyDDr3Gmjn5La0X0Ir9/eLyM+c	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32571	uniprotkb:Q96MT8-3	intact:EBI-19840|uniprotkb:D6VS55|ensemblfungi:YDR069C	intact:EBI-11522539|ensembl:ENSP00000507703|ensembl:ENSP00000328382|ensembl:ENSP00000506728|ensembl:ENSP00000506791|ensembl:ENSP00000506828|ensembl:ENSP00000507228	psi-mi:ubp4_yeast(display_long)|uniprotkb:DOA4(gene name)|psi-mi:DOA4(display_short)|uniprotkb:MUT4(gene name synonym)|uniprotkb:SSV7(gene name synonym)|uniprotkb:YDR069C(locus name)|uniprotkb:YD9609.23C(orf name)|uniprotkb:YD8554.02C(orf name)|uniprotkb:D4270(orf name)|uniprotkb:NPI2(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 4(gene name synonym)|uniprotkb:Deubiquitinating enzyme 4(gene name synonym)|uniprotkb:Vacuole biogenesis protein SSV7(gene name synonym)|uniprotkb:Ubiquitin thioesterase 4(gene name synonym)|uniprotkb:DOS1(gene name synonym)|uniprotkb:UBP4(gene name synonym)	psi-mi:q96mt8-3(display_long)|uniprotkb:CEP63(gene name)|psi-mi:CEP63(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11555911|imex:IM-24995-4458	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002476|ensemblfungi:YDR069C(gene)|ensemblfungi:YDR069C_mRNA(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005739"(mitochondrion)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0010992"(ubiquitin recycling)|go:"GO:0010995"(free ubiquitin chain depolymerization)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0031902"(late endosome membrane)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0070676"(intralumenal vesicle formation)|go:"GO:1904669"(ATP export)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR001763(Rhodanese-like)|interpro:IPR018200|interpro:IPR028889|interpro:IPR036873|interpro:IPR038765|refseq:NP_010354.3|dip:DIP-5298N|mint:P32571|sgd:YDR069C(identity)	intact:EBI-741977(isoform-parent)|ensembl:ENST00000332047(transcript)|ensembl:ENST00000682042(transcript)|ensembl:ENST00000682800(transcript)|ensembl:ENST00000682858(transcript)|ensembl:ENST00000683177(transcript)|ensembl:ENST00000683861(transcript)|ensembl:ENSG00000182923(gene)|uniprotkb:Q96MT8-3(isoform-parent)|entrezgene/locuslink:80254(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:UTBSWmpygyxo1ygxp/sQ8wgqnMo559292	rogid:U0uvVcOCzA8Qp2cCB0ilixgd4Yc9606	intact-crc:1C81BE8F45DE3D42|rigid:kI8D2HOV+rSIzOY7Cz4dnMIPdhc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96ED9-2	uniprotkb:P32571	intact:EBI-10961706|ensembl:ENSP00000264827	intact:EBI-19840|uniprotkb:D6VS55|ensemblfungi:YDR069C	psi-mi:q96ed9-2(display_long)|uniprotkb:HOOK2(gene name)|psi-mi:HOOK2(display_short)	psi-mi:ubp4_yeast(display_long)|uniprotkb:DOA4(gene name)|psi-mi:DOA4(display_short)|uniprotkb:MUT4(gene name synonym)|uniprotkb:SSV7(gene name synonym)|uniprotkb:YDR069C(locus name)|uniprotkb:YD9609.23C(orf name)|uniprotkb:YD8554.02C(orf name)|uniprotkb:D4270(orf name)|uniprotkb:NPI2(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 4(gene name synonym)|uniprotkb:Deubiquitinating enzyme 4(gene name synonym)|uniprotkb:Vacuole biogenesis protein SSV7(gene name synonym)|uniprotkb:Ubiquitin thioesterase 4(gene name synonym)|uniprotkb:DOS1(gene name synonym)|uniprotkb:UBP4(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11555902|imex:IM-24995-4457	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000095066(gene)|ensembl:ENST00000264827(transcript)|intact:EBI-743290(isoform-parent)|uniprotkb:Q96ED9-2(isoform-parent)|entrezgene/locuslink:29911(identity)	sgd:S000002476|ensemblfungi:YDR069C(gene)|ensemblfungi:YDR069C_mRNA(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005739"(mitochondrion)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0010992"(ubiquitin recycling)|go:"GO:0010995"(free ubiquitin chain depolymerization)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0031902"(late endosome membrane)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0070676"(intralumenal vesicle formation)|go:"GO:1904669"(ATP export)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR001763(Rhodanese-like)|interpro:IPR018200|interpro:IPR028889|interpro:IPR036873|interpro:IPR038765|refseq:NP_010354.3|dip:DIP-5298N|mint:P32571|sgd:YDR069C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:aJZ/iDJpRk5dFL1NiouLuTjnOnc9606	rogid:UTBSWmpygyxo1ygxp/sQ8wgqnMo559292	intact-crc:F2DF2588BAEA876B|rigid:u6BwzFlMwt2j4xi/nZM8QYjxRkI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32571	uniprotkb:Q8N6Y0	intact:EBI-19840|uniprotkb:D6VS55|ensemblfungi:YDR069C	intact:EBI-739895|uniprotkb:Q8NBX7|uniprotkb:Q96KH3|uniprotkb:Q9BYI8|uniprotkb:A8K7L6|uniprotkb:B2RCR9|ensembl:ENSP00000252597	psi-mi:ubp4_yeast(display_long)|uniprotkb:DOA4(gene name)|psi-mi:DOA4(display_short)|uniprotkb:MUT4(gene name synonym)|uniprotkb:SSV7(gene name synonym)|uniprotkb:YDR069C(locus name)|uniprotkb:YD9609.23C(orf name)|uniprotkb:YD8554.02C(orf name)|uniprotkb:D4270(orf name)|uniprotkb:NPI2(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 4(gene name synonym)|uniprotkb:Deubiquitinating enzyme 4(gene name synonym)|uniprotkb:Vacuole biogenesis protein SSV7(gene name synonym)|uniprotkb:Ubiquitin thioesterase 4(gene name synonym)|uniprotkb:DOS1(gene name synonym)|uniprotkb:UBP4(gene name synonym)	psi-mi:usbp1_human(display_long)|uniprotkb:USHBP1(gene name)|psi-mi:USHBP1(display_short)|uniprotkb:MCC-2(gene name synonym)|uniprotkb:AIE-75-binding protein(gene name synonym)|uniprotkb:AIEBP(gene name synonym)|uniprotkb:MCC2(gene name synonym)|uniprotkb:Mutated in colon cancer protein 2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11555893|imex:IM-24995-4456	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002476|ensemblfungi:YDR069C(gene)|ensemblfungi:YDR069C_mRNA(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005739"(mitochondrion)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0010992"(ubiquitin recycling)|go:"GO:0010995"(free ubiquitin chain depolymerization)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0031902"(late endosome membrane)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0070676"(intralumenal vesicle formation)|go:"GO:1904669"(ATP export)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR001763(Rhodanese-like)|interpro:IPR018200|interpro:IPR028889|interpro:IPR036873|interpro:IPR038765|refseq:NP_010354.3|dip:DIP-5298N|mint:P32571|sgd:YDR069C(identity)	refseq:NP_001284632.1|refseq:NP_114147.2|refseq:NP_001308346.1|ensembl:ENSG00000130307(gene)|ensembl:ENST00000252597(transcript)|go:"GO:0030165"(PDZ domain binding)|interpro:IPR019536|interpro:IPR040171|entrezgene/locuslink:83878(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:UTBSWmpygyxo1ygxp/sQ8wgqnMo559292	rogid:vY1qx73Ju/z7WDu6k1kd10ZDVRo9606	intact-crc:9816B50F8FD0FEAA|rigid:DN8zgK0GuI+aCXH3yiBoVoqrj3U	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32571	uniprotkb:Q5JR59-3	intact:EBI-19840|uniprotkb:D6VS55|ensemblfungi:YDR069C	intact:EBI-11522433|ensembl:ENSP00000370186	psi-mi:ubp4_yeast(display_long)|uniprotkb:DOA4(gene name)|psi-mi:DOA4(display_short)|uniprotkb:MUT4(gene name synonym)|uniprotkb:SSV7(gene name synonym)|uniprotkb:YDR069C(locus name)|uniprotkb:YD9609.23C(orf name)|uniprotkb:YD8554.02C(orf name)|uniprotkb:D4270(orf name)|uniprotkb:NPI2(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 4(gene name synonym)|uniprotkb:Deubiquitinating enzyme 4(gene name synonym)|uniprotkb:Vacuole biogenesis protein SSV7(gene name synonym)|uniprotkb:Ubiquitin thioesterase 4(gene name synonym)|uniprotkb:DOS1(gene name synonym)|uniprotkb:UBP4(gene name synonym)	psi-mi:q5jr59-3(display_long)|uniprotkb:MTUS2(gene name)|psi-mi:MTUS2(display_short)|uniprotkb:CAZIP(gene name synonym)|uniprotkb:Cardiac zipper protein(gene name synonym)|uniprotkb:KIAA0774(gene name synonym)|uniprotkb:Microtubule plus-end tracking protein TIP150(gene name synonym)|uniprotkb:TIP150(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11555884|imex:IM-24995-4455	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002476|ensemblfungi:YDR069C(gene)|ensemblfungi:YDR069C_mRNA(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005739"(mitochondrion)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0010992"(ubiquitin recycling)|go:"GO:0010995"(free ubiquitin chain depolymerization)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0031902"(late endosome membrane)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0070676"(intralumenal vesicle formation)|go:"GO:1904669"(ATP export)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR001763(Rhodanese-like)|interpro:IPR018200|interpro:IPR028889|interpro:IPR036873|interpro:IPR038765|refseq:NP_010354.3|dip:DIP-5298N|mint:P32571|sgd:YDR069C(identity)	ensembl:ENSG00000132938(gene)|ensembl:ENST00000380808(transcript)|intact:EBI-742948(isoform-parent)|uniprotkb:Q5JR59-3(isoform-parent)|entrezgene/locuslink:23281(identity)	-	-	isoform-comment:No experimental confirmation available.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:UTBSWmpygyxo1ygxp/sQ8wgqnMo559292	rogid:npId9tC7VoLN/jteoBiRbSYChPs9606	intact-crc:521401AB1F9E6A1F|rigid:mEWh4UkwNk8Pil//vX8dQyZ9SAA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32571	uniprotkb:Q15025	intact:EBI-19840|uniprotkb:D6VS55|ensemblfungi:YDR069C	intact:EBI-357849|uniprotkb:A4F1W8|uniprotkb:O76008|uniprotkb:Q96EL9|uniprotkb:Q99833|uniprotkb:Q9H1J3|uniprotkb:B7Z699|uniprotkb:Q6N077|ensembl:ENSP00000317891|ensembl:ENSP00000428187|ensembl:ENSP00000430760|uniprotkb:A4F1W9|uniprotkb:A4F1X2|uniprotkb:A4F1X4|uniprotkb:A4F1X5|uniprotkb:A4F1X6|uniprotkb:A4F1X7|uniprotkb:A4F1X9|uniprotkb:E7EPY1|uniprotkb:E7ET96|uniprotkb:Q05KP3|uniprotkb:Q05KP4	psi-mi:ubp4_yeast(display_long)|uniprotkb:DOA4(gene name)|psi-mi:DOA4(display_short)|uniprotkb:MUT4(gene name synonym)|uniprotkb:SSV7(gene name synonym)|uniprotkb:YDR069C(locus name)|uniprotkb:YD9609.23C(orf name)|uniprotkb:YD8554.02C(orf name)|uniprotkb:D4270(orf name)|uniprotkb:NPI2(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 4(gene name synonym)|uniprotkb:Deubiquitinating enzyme 4(gene name synonym)|uniprotkb:Vacuole biogenesis protein SSV7(gene name synonym)|uniprotkb:Ubiquitin thioesterase 4(gene name synonym)|uniprotkb:DOS1(gene name synonym)|uniprotkb:UBP4(gene name synonym)	psi-mi:tnip1_human(display_long)|uniprotkb:TNIP1(gene name)|psi-mi:TNIP1(display_short)|uniprotkb:KIAA0113(gene name synonym)|uniprotkb:NAF1(gene name synonym)|uniprotkb:Nef-associated factor 1(gene name synonym)|uniprotkb:HIV-1 Nef-interacting protein(gene name synonym)|uniprotkb:Virion-associated nuclear shuttling protein(gene name synonym)|uniprotkb:Nip40-1(gene name synonym)|uniprotkb:A20-binding inhibitor of NF-kappa-B activation 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11555874|imex:IM-24995-4454	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002476|ensemblfungi:YDR069C(gene)|ensemblfungi:YDR069C_mRNA(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005739"(mitochondrion)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0010992"(ubiquitin recycling)|go:"GO:0010995"(free ubiquitin chain depolymerization)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0031902"(late endosome membrane)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0070676"(intralumenal vesicle formation)|go:"GO:1904669"(ATP export)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR001763(Rhodanese-like)|interpro:IPR018200|interpro:IPR028889|interpro:IPR036873|interpro:IPR038765|refseq:NP_010354.3|dip:DIP-5298N|mint:P32571|sgd:YDR069C(identity)	refseq:NP_006049.3|refseq:NP_001239319.1|refseq:NP_001239320.1|refseq:NP_001239321.1|refseq:NP_001239322.1|refseq:NP_001245383.1|dip:DIP-27577N|refseq:NP_001239315.1|ensembl:ENSG00000145901(gene)|ensembl:ENST00000315050(transcript)|ensembl:ENST00000521591(transcript)|ensembl:ENST00000522226(transcript)|go:"GO:0002755"(MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0006952"(defense response)|go:"GO:0006954"(inflammatory response)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0009101"(glycoprotein biosynthetic process)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0085032"(modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade)|go:"GO:1903003"(positive regulation of protein deubiquitination)|interpro:IPR033372|mint:Q15025|reactome:R-HSA-5689896|go:"GO:0051019"(mitogen-activated protein kinase binding)|refseq:NP_001239314.1|refseq:NP_001245384.1|refseq:NP_001245385.1|refseq:XP_006714814.1|refseq:XP_006714815.1|entrezgene/locuslink:10318(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:UTBSWmpygyxo1ygxp/sQ8wgqnMo559292	rogid:16Vjb5CuGTAbW2M22qbCxgXtV1o9606	intact-crc:307E2852F256C4E8|rigid:ijitWknNv+h+mXOvzIRz19XPe8A	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O94972	uniprotkb:P32571	intact:EBI-741602|uniprotkb:Q7Z3E6|uniprotkb:Q8IYF7|uniprotkb:Q8WYF7|intact:EBI-28976055|ensembl:ENSP00000262294|ensembl:ENSP00000376785|uniprotkb:A8K0V9|uniprotkb:A8K8U4|uniprotkb:A8MZ79|uniprotkb:B4DGZ3|uniprotkb:F8WEE6	intact:EBI-19840|uniprotkb:D6VS55|ensemblfungi:YDR069C	psi-mi:tri37_human(display_long)|uniprotkb:Mulibrey nanism protein(gene name synonym)|uniprotkb:TRIM37(gene name)|psi-mi:TRIM37(display_short)|uniprotkb:KIAA0898(gene name synonym)|uniprotkb:MUL(gene name synonym)|uniprotkb:POB1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 37(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM37(gene name synonym)	psi-mi:ubp4_yeast(display_long)|uniprotkb:DOA4(gene name)|psi-mi:DOA4(display_short)|uniprotkb:MUT4(gene name synonym)|uniprotkb:SSV7(gene name synonym)|uniprotkb:YDR069C(locus name)|uniprotkb:YD9609.23C(orf name)|uniprotkb:YD8554.02C(orf name)|uniprotkb:D4270(orf name)|uniprotkb:NPI2(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 4(gene name synonym)|uniprotkb:Deubiquitinating enzyme 4(gene name synonym)|uniprotkb:Vacuole biogenesis protein SSV7(gene name synonym)|uniprotkb:Ubiquitin thioesterase 4(gene name synonym)|uniprotkb:DOS1(gene name synonym)|uniprotkb:UBP4(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11555865|imex:IM-24995-4453	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001005207.1|refseq:NP_056109.1|refseq:NP_001307916.1|ensembl:ENSP00000262294|ensembl:ENST00000393065|ensembl:ENSP00000376784|ensembl:ENSP00000376785|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046600"(negative regulation of centriole replication)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070842"(aggresome assembly)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002083(MATH)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR008974(TRAF-like)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR037299|rcsb pdb:3LRQ|reactome:R-HSA-983168|ensembl:ENSG00000108395(gene)|ensembl:ENST00000262294(transcript)|ensembl:ENST00000393066(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005777"(peroxisome)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016235"(aggresome)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0035518"(histone H2A monoubiquitination)|refseq:NP_001307919.1|dip:DIP-34437N|entrezgene/locuslink:4591(identity)	sgd:S000002476|ensemblfungi:YDR069C(gene)|ensemblfungi:YDR069C_mRNA(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005739"(mitochondrion)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0010992"(ubiquitin recycling)|go:"GO:0010995"(free ubiquitin chain depolymerization)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0031902"(late endosome membrane)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0070676"(intralumenal vesicle formation)|go:"GO:1904669"(ATP export)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR001763(Rhodanese-like)|interpro:IPR018200|interpro:IPR028889|interpro:IPR036873|interpro:IPR038765|refseq:NP_010354.3|dip:DIP-5298N|mint:P32571|sgd:YDR069C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:y2njeO0MUBrKU9MUvkbo1uZmqkE9606	rogid:UTBSWmpygyxo1ygxp/sQ8wgqnMo559292	intact-crc:4AD91D621BE3020D|rigid:Fip2dzLdN2rSbGgYxEH7/vyk+oU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32571	intact:EBI-11523568	intact:EBI-19840|uniprotkb:D6VS55|ensemblfungi:YDR069C	-	psi-mi:ubp4_yeast(display_long)|uniprotkb:DOA4(gene name)|psi-mi:DOA4(display_short)|uniprotkb:MUT4(gene name synonym)|uniprotkb:SSV7(gene name synonym)|uniprotkb:YDR069C(locus name)|uniprotkb:YD9609.23C(orf name)|uniprotkb:YD8554.02C(orf name)|uniprotkb:D4270(orf name)|uniprotkb:NPI2(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 4(gene name synonym)|uniprotkb:Deubiquitinating enzyme 4(gene name synonym)|uniprotkb:Vacuole biogenesis protein SSV7(gene name synonym)|uniprotkb:Ubiquitin thioesterase 4(gene name synonym)|uniprotkb:DOS1(gene name synonym)|uniprotkb:UBP4(gene name synonym)	psi-mi:nav2(display_short)|psi-mi:EBI-11523568(display_long)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11555856|imex:IM-24995-4452	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002476|ensemblfungi:YDR069C(gene)|ensemblfungi:YDR069C_mRNA(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005739"(mitochondrion)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0010992"(ubiquitin recycling)|go:"GO:0010995"(free ubiquitin chain depolymerization)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0031902"(late endosome membrane)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0070676"(intralumenal vesicle formation)|go:"GO:1904669"(ATP export)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR001763(Rhodanese-like)|interpro:IPR018200|interpro:IPR028889|interpro:IPR036873|interpro:IPR038765|refseq:NP_010354.3|dip:DIP-5298N|mint:P32571|sgd:YDR069C(identity)	entrezgene/locuslink:89797(identity)	-	-	no-uniprot-update:	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:UTBSWmpygyxo1ygxp/sQ8wgqnMo559292	rogid:WyH5VrQlZ4x7Sr5Hd4ApJ74qrL49606	intact-crc:0CFD229EC6BF5B08|rigid:mFA8pUXslEx569AJcgdfELXftIE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96M27	uniprotkb:P32562	intact:EBI-2560879|intact:EBI-28987821|uniprotkb:Q8NEZ7|uniprotkb:Q86Y42|uniprotkb:Q69YM8|uniprotkb:Q7L2U7|uniprotkb:Q96AJ3|uniprotkb:Q8IVL4|uniprotkb:Q8IVJ4|ensembl:ENSP00000296666	intact:EBI-4440|ensemblfungi:YMR001C|uniprotkb:D6VZH5	psi-mi:prrc1_human(display_long)|uniprotkb:PRRC1(gene name)|psi-mi:PRRC1(display_short)|uniprotkb:Proline-rich and coiled-coil-containing protein 1(gene name synonym)	psi-mi:cdc5_yeast(display_long)|uniprotkb:CDC5(gene name)|psi-mi:CDC5(display_short)|uniprotkb:MSD2(gene name synonym)|uniprotkb:PKX2(gene name synonym)|uniprotkb:YMR001C(locus name)|uniprotkb:YM8270.03C(orf name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11555847|imex:IM-24995-4451	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_570721.1|refseq:NP_001273737.1|ensembl:ENSP00000296666|ensembl:ENST00000442138|ensembl:ENSP00000392873|ensembl:ENST00000512635|ensembl:ENSP00000421965|refseq:XP_006714592.1|ensembl:ENSG00000164244(gene)|ensembl:ENST00000296666(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0034199"(activation of protein kinase A activity)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|interpro:IPR026533|interpro:IPR026534|interpro:IPR029001|mint:Q96M27|entrezgene/locuslink:133619(identity)	ensemblfungi:YMR001C(gene)|ensemblfungi:YMR001C_mRNA(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0000922"(spindle pole)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0010458"(exit from mitosis)|go:"GO:0010696"(positive regulation of mitotic spindle pole body separation)|go:"GO:0019237"(centromeric DNA binding)|refseq:NP_013714.1|sgd:S000004603|reactome:R-SCE-6804115|reactome:R-SCE-156711|reactome:R-SCE-162658|reactome:R-SCE-2565942|dip:DIP-2321N|reactome:R-SCE-2500257|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0035025"(positive regulation of Rho protein signal transduction)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051301"(cell division)|go:"GO:0070194"(synaptonemal complex disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0110083"(positive regulation of protein localization to cell division site involved in mitotic actomyosin contractile ring assembly)|go:"GO:1902542"(regulation of protein localization to mitotic spindle pole body)|go:"GO:1903353"(regulation of nucleus organization)|go:"GO:1904750"(negative regulation of protein localization to nucleolus)|go:"GO:1905339"(positive regulation of cohesin unloading)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033695|interpro:IPR033701|interpro:IPR036947|rcsb pdb:6MF4|rcsb pdb:6MF5|rcsb pdb:6MF6|sgd:YMR001C(identity)	-	-	crc64:B5A25F1BBBEAA3DC	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:PLR9r6Zo0BDrdOArwQjuDiVPIik9606	rogid:XXSkltYvBA9Zkh0Kr5s1znazUC0559292	intact-crc:830AAC662A96C38E|rigid:VWvzr7qeIgW0D1wCs3qAY4B3Ng8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P26641	uniprotkb:P32601	intact:EBI-351467|uniprotkb:Q6PJ62|uniprotkb:Q6PK31|uniprotkb:Q96CU2|uniprotkb:Q9P196|intact:EBI-2321928|uniprotkb:B4DTG2|ensembl:ENSP00000331901	intact:EBI-6178|uniprotkb:Q12299|uniprotkb:Q3S1N1|uniprotkb:D6W427|ensemblfungi:YPR017C	psi-mi:ef1g_human(display_long)|uniprotkb:PRO1608(orf name)|uniprotkb:EEF1G(gene name)|psi-mi:EEF1G(display_short)|uniprotkb:EF1G(gene name synonym)|uniprotkb:eEF-1B gamma(gene name synonym)	psi-mi:dss4_yeast(display_long)|uniprotkb:DSS4(gene name)|psi-mi:DSS4(display_short)|uniprotkb:LPZ16C(orf name)|uniprotkb:YP9531.11C(orf name)|uniprotkb:YPR017C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11555947|imex:IM-24995-4462	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001395.1|ensembl:ENSG00000254772(gene)|ensembl:ENST00000329251(transcript)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006414"(translational elongation)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001662(Translation elongation factor EF1B, gamma chain, conserved)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR036249|interpro:IPR036282|interpro:IPR036433|interpro:IPR040079|mint:P26641|rcsb pdb:1PBU|rcsb pdb:5DQS|rcsb pdb:5JPO|reactome:R-HSA-156842|dip:DIP-32516N|entrezgene/locuslink:1937(identity)	refseq:NP_015342.1|sgd:S000006221|dip:DIP-1423N|ensemblfungi:YPR017C(gene)|ensemblfungi:YPR017C_mRNA(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008270"(zinc ion binding)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|interpro:IPR007515(Mss4)|interpro:IPR011057(Mss4-like)|interpro:IPR011323(Mss4/translationally controlled tumour-associated TCTP)|sgd:YPR017C(identity)	-	-	crc64:1D7B6D3443D93AE2	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:biVN96umeEdPm/wvPN4VwbSRHTs9606	rogid:UKF+4mfZLTZ2s5CLkImTGcwgvUw559292	intact-crc:EE182FFF22F15364|rigid:EvKgM1/2L6A7SHxeu5xsDJiMmf4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q99750	uniprotkb:P32589	intact:EBI-724076|ensembl:ENSP00000230321|ensembl:ENSP00000362142	intact:EBI-8648|uniprotkb:D6W3R1|ensemblfungi:YPL106C	psi-mi:mdfi_human(display_long)|uniprotkb:Myogenic repressor I-mf(gene name synonym)|uniprotkb:MDFI(gene name)|psi-mi:MDFI(display_short)	psi-mi:hsp7f_yeast(display_long)|uniprotkb:SSE1(gene name)|psi-mi:SSE1(display_short)|uniprotkb:MSI3(gene name synonym)|uniprotkb:YPL106C(locus name)|uniprotkb:LPG3C(orf name)|uniprotkb:Chaperone protein MSI3(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11555938|imex:IM-24995-4461	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005577.1|ensembl:ENSG00000112559(gene)|ensembl:ENST00000230321(transcript)|ensembl:ENST00000373051(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR026134|mint:Q99750|refseq:NP_001287733.1|refseq:NP_001287734.1|refseq:NP_001287735.1|entrezgene/locuslink:4188(identity)	refseq:NP_015219.1|sgd:S000006027|mint:P32589|dip:DIP-6645N|ensemblfungi:YPL106C(gene)|ensemblfungi:YPL106C_mRNA(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0006457"(protein folding)|go:"GO:0006914"(autophagy)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0042026"(protein refolding)|go:"GO:0042277"(peptide binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|rcsb pdb:2QXL|rcsb pdb:3C7N|rcsb pdb:3D2E|rcsb pdb:3D2F|sgd:YPL106C(identity)	-	-	crc64:6558259111B0BC38	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:V3vU0fihMOW18DMHAiDbuZ3asNU9606	rogid:16yTg05haoflKGNZTW4EqC7FSs0559292	intact-crc:30E23FA2E9BD62F3|rigid:p5E3oQwlivMCNoDUDVqTwze95nY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9Y6D9	uniprotkb:P32571	intact:EBI-742610|uniprotkb:B3KR41|uniprotkb:Q9UNH0|uniprotkb:Q13312|uniprotkb:Q75MI0|uniprotkb:Q86UM4|ensembl:ENSP00000265854|ensembl:ENSP00000382562|ensembl:ENSP00000385334	intact:EBI-19840|uniprotkb:D6VS55|ensemblfungi:YDR069C	psi-mi:md1l1_human(display_long)|uniprotkb:Mitotic arrest deficient 1-like protein 1(gene name synonym)|uniprotkb:Mitotic checkpoint MAD1 protein homolog(gene name synonym)|uniprotkb:Tax-binding protein 181(gene name synonym)|uniprotkb:MAD1L1(gene name)|psi-mi:MAD1L1(display_short)|uniprotkb:MAD1(gene name synonym)|uniprotkb:TXBP181(gene name synonym)	psi-mi:ubp4_yeast(display_long)|uniprotkb:DOA4(gene name)|psi-mi:DOA4(display_short)|uniprotkb:MUT4(gene name synonym)|uniprotkb:SSV7(gene name synonym)|uniprotkb:YDR069C(locus name)|uniprotkb:YD9609.23C(orf name)|uniprotkb:YD8554.02C(orf name)|uniprotkb:D4270(orf name)|uniprotkb:NPI2(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 4(gene name synonym)|uniprotkb:Deubiquitinating enzyme 4(gene name synonym)|uniprotkb:Vacuole biogenesis protein SSV7(gene name synonym)|uniprotkb:Ubiquitin thioesterase 4(gene name synonym)|uniprotkb:DOS1(gene name synonym)|uniprotkb:UBP4(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11555929|imex:IM-24995-4460	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001013858.1|refseq:NP_001013859.1|refseq:NP_003541.2|refseq:NP_001291452.1|refseq:NP_001291453.1|ensembl:ENSG00000002822(gene)|ensembl:ENST00000265854(transcript)|go:"GO:0090235"(regulation of metaphase plate congression)|go:"GO:1902426"(deactivation of mitotic spindle assembly checkpoint)|interpro:IPR008672(Mitotic checkpoint)|mint:Q9Y6D9|rcsb pdb:1GO4|rcsb pdb:4DZO|rcsb pdb:7B1F|rcsb pdb:7B1H|rcsb pdb:7B1J|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|ensembl:ENST00000399654(transcript)|ensembl:ENST00000406869(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043515"(kinetochore binding)|go:"GO:0044615"(nuclear pore nuclear basket)|go:"GO:0048538"(thymus development)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0072686"(mitotic spindle)|refseq:XP_005249934.1|dip:DIP-29654N|entrezgene/locuslink:8379(identity)	sgd:S000002476|ensemblfungi:YDR069C(gene)|ensemblfungi:YDR069C_mRNA(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005739"(mitochondrion)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0010992"(ubiquitin recycling)|go:"GO:0010995"(free ubiquitin chain depolymerization)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0031902"(late endosome membrane)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0070676"(intralumenal vesicle formation)|go:"GO:1904669"(ATP export)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR001763(Rhodanese-like)|interpro:IPR018200|interpro:IPR028889|interpro:IPR036873|interpro:IPR038765|refseq:NP_010354.3|dip:DIP-5298N|mint:P32571|sgd:YDR069C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:9CcqpZlN0IgqC939rIo7vNgOvLQ9606	rogid:UTBSWmpygyxo1ygxp/sQ8wgqnMo559292	intact-crc:493D08D22DC8CB81|rigid:SJ0gDSH+tfkGAInWADUpSnggA8Y	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32622	uniprotkb:P19474	intact:EBI-22350|uniprotkb:D3DLK8|ensemblfungi:YEL041W	intact:EBI-81290|uniprotkb:Q96RF8|uniprotkb:Q5XPV5|ensembl:ENSP00000254436	psi-mi:yef1_yeast(display_long)|uniprotkb:YEF1(gene name)|psi-mi:YEF1(display_short)|uniprotkb:SYGP-ORF17(orf name)|uniprotkb:YEL041W(locus name)	psi-mi:ro52_human(display_long)|uniprotkb:TRIM21(gene name)|psi-mi:TRIM21(display_short)|uniprotkb:RNF81(gene name synonym)|uniprotkb:Sjoegren syndrome type A antigen(gene name synonym)|uniprotkb:"Ro(SS-A)"(gene name synonym)|uniprotkb:52 kDa ribonucleoprotein autoantigen Ro/SS-A(gene name synonym)|uniprotkb:Tripartite motif-containing protein 21(gene name synonym)|uniprotkb:RING finger protein 81(gene name synonym)|uniprotkb:52 kDa Ro protein(gene name synonym)|uniprotkb:RO52(gene name synonym)|uniprotkb:SSA1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM21(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11556010|imex:IM-24995-4469	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010873.1|sgd:S000000767|dip:DIP-1885N|mint:P32622|ensemblfungi:YEL041W(gene)|ensemblfungi:YEL041W_mRNA(transcript)|go:"GO:0003951"(NAD+ kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006741"(NADP biosynthetic process)|go:"GO:0019674"(NAD metabolic process)|go:"GO:0042736"(NADH kinase activity)|interpro:IPR002504(ATP-NAD/AcoX kinase)|interpro:IPR016064(ATP-NAD kinase, PpnK-type)|interpro:IPR017437(ATP-NAD kinase, PpnK-type, all-beta)|interpro:IPR017438(ATP-NAD kinase, PpnK-type, alpha/beta)|sgd:YEL041W(identity)	refseq:NP_003132.2|go:"GO:0019901"(protein kinase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031648"(protein destabilization)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032479"(regulation of type I interferon production)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045824"(negative regulation of innate immune response)|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046598"(positive regulation of viral entry into host cell)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0090086"(negative regulation of protein deubiquitination)|ensembl:ENSG00000132109(gene)|ensembl:ENST00000254436(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000932"(P-body)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0007049"(cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR020457|interpro:IPR035831|interpro:IPR043136|mint:P19474|rcsb pdb:2IWG|rcsb pdb:5JPX|rcsb pdb:5OLM|rcsb pdb:6FGA|rcsb pdb:6S53|rcsb pdb:7BBD|reactome:R-HSA-1834941|reactome:R-HSA-3134975|reactome:R-HSA-877300|reactome:R-HSA-983168|go:"GO:1902187"|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003613(U box)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|entrezgene/locuslink:6737(identity)	-	crc64:E8301D466249DA27	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:HAL9emGKdVRCmdDG9CMzn68CGUI559292	rogid:/9rpwdudXQWv8z8JLmRecXf3YQM9606	intact-crc:751693B6CB8F15EB|rigid:gt8pj4ZDFSCdBUapixL/5NGgO+s	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O95544	uniprotkb:P32622	intact:EBI-743949|uniprotkb:Q9H931|uniprotkb:A8K296|uniprotkb:A6NNN3|uniprotkb:B7Z434|uniprotkb:F5GXR5|uniprotkb:Q5QPS4|uniprotkb:Q9H2P2|ensembl:ENSP00000341679|ensembl:ENSP00000344340	intact:EBI-22350|uniprotkb:D3DLK8|ensemblfungi:YEL041W	psi-mi:nadk_human(display_long)|uniprotkb:"Poly(P)/ATP NAD kinase"(gene name synonym)|uniprotkb:NADK(gene name)|psi-mi:NADK(display_short)	psi-mi:yef1_yeast(display_long)|uniprotkb:YEF1(gene name)|psi-mi:YEF1(display_short)|uniprotkb:SYGP-ORF17(orf name)|uniprotkb:YEL041W(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11556001|imex:IM-24995-4468	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001185922.1|refseq:NP_001185923.1|refseq:NP_001185924.1|refseq:NP_075394.3|refseq:XP_005244835.1|refseq:XP_006710900.1|ensembl:ENSG00000008130(gene)|ensembl:ENST00000341426(transcript)|ensembl:ENST00000341991(transcript)|go:"GO:0003951"(NAD+ kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006741"(NADP biosynthetic process)|go:"GO:0016310"(phosphorylation)|go:"GO:0019674"(NAD metabolic process)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046872"(metal ion binding)|interpro:IPR002504(ATP-NAD/AcoX kinase)|interpro:IPR016064(ATP-NAD kinase, PpnK-type)|interpro:IPR017437(ATP-NAD kinase, PpnK-type, all-beta)|interpro:IPR017438(ATP-NAD kinase, PpnK-type, alpha/beta)|mint:O95544|rcsb pdb:3PFN|reactome:R-HSA-196807|entrezgene/locuslink:65220(identity)	refseq:NP_010873.1|sgd:S000000767|dip:DIP-1885N|mint:P32622|ensemblfungi:YEL041W(gene)|ensemblfungi:YEL041W_mRNA(transcript)|go:"GO:0003951"(NAD+ kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006741"(NADP biosynthetic process)|go:"GO:0019674"(NAD metabolic process)|go:"GO:0042736"(NADH kinase activity)|interpro:IPR002504(ATP-NAD/AcoX kinase)|interpro:IPR016064(ATP-NAD kinase, PpnK-type)|interpro:IPR017437(ATP-NAD kinase, PpnK-type, all-beta)|interpro:IPR017438(ATP-NAD kinase, PpnK-type, alpha/beta)|sgd:YEL041W(identity)	-	-	crc64:E8301D466249DA27	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:XPfRviZiKsV+1JOUi7BsMrIa3M49606	rogid:HAL9emGKdVRCmdDG9CMzn68CGUI559292	intact-crc:60C662613F9C9BC4|rigid:/mJyZP7jnOwR5pOfg2RO3cVZgVU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q15102	uniprotkb:P32614	intact:EBI-711522|uniprotkb:Q53X88|ensembl:ENSP00000262890|ensembl:ENSP00000444935	intact:EBI-22366|uniprotkb:D3DLK3|ensemblfungi:YEL047C	psi-mi:pa1b3_human(display_long)|uniprotkb:PAFAH1B3(gene name)|psi-mi:PAFAH1B3(display_short)|uniprotkb:PAFAHG(gene name synonym)|uniprotkb:PAF acetylhydrolase 29 kDa subunit(gene name synonym)|uniprotkb:PAF-AH subunit gamma(gene name synonym)	psi-mi:frds_yeast(display_long)|uniprotkb:FRD1(gene name)|psi-mi:FRD1(display_short)|uniprotkb:FAD-dependent oxidoreductase(gene name synonym)|uniprotkb:FRDS(gene name synonym)|uniprotkb:FRDS1(gene name synonym)|uniprotkb:NADH-dependent fumarate reductase(gene name synonym)|uniprotkb:Soluble fumarate reductase, cytoplasmic isozyme(gene name synonym)|uniprotkb:SYGP-ORF35(orf name)|uniprotkb:YEL047C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11555992|imex:IM-24995-4467	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016042"(lipid catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0047179"(platelet-activating factor acetyltransferase activity)|interpro:IPR013830(Esterase, SGNH hydrolase-type)|interpro:IPR036514|mint:Q15102|reactome:R-HSA-6811436|go:"GO:0005829"(cytosol)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0008247"(1-alkyl-2-acetylglycerophosphocholine esterase complex)|go:"GO:0016020"(membrane)|ensembl:ENSG00000079462(gene)|ensembl:ENST00000262890(transcript)|ensembl:ENST00000538771(transcript)|go:"GO:0003847"(1-alkyl-2-acetylglycerophosphocholine esterase activity)|go:"GO:0005737"(cytoplasm)|refseq:NP_001139411.1|refseq:NP_001139412.1|refseq:NP_002564.1|entrezgene/locuslink:5050(identity)	sgd:S000000773|refseq:NP_010867.3|dip:DIP-5287N|mint:P32614|ensemblfungi:YEL047C(gene)|ensemblfungi:YEL047C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010181"(FMN binding)|go:"GO:0016156"("fumarate reductase (NADH) activity")|go:"GO:0071454"(cellular response to anoxia)|interpro:IPR003953(Fumarate reductase/succinate dehydrogenase flavoprotein, N-terminal)|interpro:IPR010960(Flavocytochrome c)|interpro:IPR027477|interpro:IPR036188|sgd:YEL047C(identity)	-	-	crc64:63C30B39252DC935	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:yxVKkXAs2AmH+fZFUW+hZN889k89606	rogid:hkn/l2LN9LMWWw+e7kXvRXVqvr4559292	intact-crc:F3B3C002B7DEDC52|rigid:sZ95JGMiTAmt5QKEhbl5f/wX+OE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9BUW7	uniprotkb:P32610	intact:EBI-752084|uniprotkb:Q9Y3F7|uniprotkb:Q5SYV8|ensembl:ENSP00000362085	intact:EBI-20264|uniprotkb:D3DLJ9|ensemblfungi:YEL051W	psi-mi:bbln_human(display_long)|uniprotkb:BBLN(gene name)|psi-mi:BBLN(display_short)|uniprotkb:C9orf16(gene name synonym)|uniprotkb:UPF0184 protein C9orf16(gene name synonym)|uniprotkb:EST00098(orf name)	psi-mi:vatd_yeast(display_long)|uniprotkb:VMA8(gene name)|psi-mi:VMA8(display_short)|uniprotkb:YEL051W(locus name)|uniprotkb:SYGP-ORF11(orf name)|uniprotkb:Vacuolar proton pump subunit D(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11555983|imex:IM-24995-4466	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_077017.1|dip:DIP-29481N|ensembl:ENSG00000171159(gene)|ensembl:ENST00000372994(transcript)|interpro:IPR005374(Protein of unknown function UPF0184)|entrezgene/locuslink:79095(identity)	refseq:NP_010863.1|sgd:S000000777|ensemblfungi:YEL051W(gene)|ensemblfungi:YEL051W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0016471"(vacuolar proton-transporting V-type ATPase complex)|go:"GO:0033176"(proton-transporting V-type ATPase complex)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR002699(ATPase, V1/A1 complex, subunit D)|rcsb pdb:3J9T|rcsb pdb:3J9U|rcsb pdb:3J9V|rcsb pdb:4RND|rcsb pdb:5BW9|rcsb pdb:5D80|rcsb pdb:5VOX|rcsb pdb:5VOY|rcsb pdb:5VOZ|rcsb pdb:6O7V|rcsb pdb:6O7W|rcsb pdb:6O7X|reactome:R-SCE-1222556|reactome:R-SCE-6798695|reactome:R-SCE-77387|reactome:R-SCE-917977|reactome:R-SCE-9639288|dip:DIP-2959N|mint:P32610|sgd:YEL051W(identity)	-	crc64:EBE1D0AFAAD6DABB	crc64:FDE93E1FAF0AEC5B	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:O4VcHghk63gMrjyh5XKmkZovFZ49606	rogid:rrwRno7lCnDeTNwawONkGwV8Hkg559292	intact-crc:54EFBACDE3E4CA7E|rigid:HBf3s4T1v7ErHlrRAY5ESbOe+30	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96EV8	uniprotkb:P32610	intact:EBI-465804|uniprotkb:Q5THY3|uniprotkb:Q5THY4|uniprotkb:Q96NV2|intact:EBI-28986386|ensembl:ENSP00000341680|uniprotkb:Q9H0U2|uniprotkb:Q9H3J5|uniprotkb:A8K3V3	intact:EBI-20264|uniprotkb:D3DLJ9|ensemblfungi:YEL051W	psi-mi:dtbp1_human(display_long)|uniprotkb:My031(orf name)|uniprotkb:DTNBP1(gene name)|psi-mi:DTNBP1(display_short)|uniprotkb:Dystrobrevin-binding protein 1(gene name synonym)|uniprotkb:Hermansky-Pudlak syndrome 7 protein(gene name synonym)|uniprotkb:Dysbindin-1(gene name synonym)|uniprotkb:BLOC1S8(gene name synonym)|uniprotkb:Biogenesis of lysosome-related organelles complex 1 subunit 8(gene name synonym)	psi-mi:vatd_yeast(display_long)|uniprotkb:VMA8(gene name)|psi-mi:VMA8(display_short)|uniprotkb:YEL051W(locus name)|uniprotkb:SYGP-ORF11(orf name)|uniprotkb:Vacuolar proton pump subunit D(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11555974|imex:IM-24995-4465	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000047579(gene)|ensembl:ENST00000344537(transcript)|go:"GO:0001956"(positive regulation of neurotransmitter secretion)|go:"GO:0005634"(nucleus)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007596"(blood coagulation)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014059"(regulation of dopamine secretion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016528"(sarcoplasm)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0030496"(midbody)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032438"(melanosome organization)|go:"GO:0033162"(melanosome membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0043005"(neuron projection)|go:"GO:0043197"(dendritic spine)|go:"GO:0005737"(cytoplasm)|go:"GO:0043506"(regulation of JUN kinase activity)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0060155"(platelet dense granule organization)|go:"GO:0060159"(regulation of dopamine receptor signaling pathway)|go:"GO:0071901"(negative regulation of protein serine/threonine kinase activity)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR007531(Dysbindin)|reactome:R-HSA-432722|go:"GO:0048490"(anterograde synaptic vesicle transport)|refseq:NP_115498.2|refseq:NP_898861.1|refseq:NP_001258597.1|refseq:NP_001258598.1|ensembl:ENST00000338950|ensembl:ENSP00000344718|ensembl:ENSP00000341680|refseq:NP_001258596.1|entrezgene/locuslink:84062(identity)	refseq:NP_010863.1|sgd:S000000777|ensemblfungi:YEL051W(gene)|ensemblfungi:YEL051W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0016471"(vacuolar proton-transporting V-type ATPase complex)|go:"GO:0033176"(proton-transporting V-type ATPase complex)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR002699(ATPase, V1/A1 complex, subunit D)|rcsb pdb:3J9T|rcsb pdb:3J9U|rcsb pdb:3J9V|rcsb pdb:4RND|rcsb pdb:5BW9|rcsb pdb:5D80|rcsb pdb:5VOX|rcsb pdb:5VOY|rcsb pdb:5VOZ|rcsb pdb:6O7V|rcsb pdb:6O7W|rcsb pdb:6O7X|reactome:R-SCE-1222556|reactome:R-SCE-6798695|reactome:R-SCE-77387|reactome:R-SCE-917977|reactome:R-SCE-9639288|dip:DIP-2959N|mint:P32610|sgd:YEL051W(identity)	-	-	crc64:FDE93E1FAF0AEC5B	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:PBwxp1vobm9l5yGoqev97lzkMHg9606	rogid:rrwRno7lCnDeTNwawONkGwV8Hkg559292	intact-crc:922AF7D0164AA988|rigid:SIIATUHtRJRLyRIKE2irBgkXGmA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48775	uniprotkb:P32610	intact:EBI-743494|ensembl:ENSP00000444788|ensembl:ENSP00000460086|uniprotkb:A8K053	intact:EBI-20264|uniprotkb:D3DLJ9|ensemblfungi:YEL051W	psi-mi:t23o_human(display_long)|uniprotkb:Tryptophan pyrrolase(gene name synonym)|uniprotkb:Tryptophan oxygenase(gene name synonym)|uniprotkb:Tryptamin 2,3-dioxygenase(gene name synonym)|uniprotkb:TDO2(gene name)|psi-mi:TDO2(display_short)|uniprotkb:TDO(gene name synonym)|uniprotkb:Tryptophanase(gene name synonym)	psi-mi:vatd_yeast(display_long)|uniprotkb:VMA8(gene name)|psi-mi:VMA8(display_short)|uniprotkb:YEL051W(locus name)|uniprotkb:SYGP-ORF11(orf name)|uniprotkb:Vacuolar proton pump subunit D(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11555965|imex:IM-24995-4464	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000151790(gene)|ensembl:ENSG00000262635(gene)|ensembl:ENST00000536354(transcript)|ensembl:ENST00000573403(transcript)|go:"GO:0004833"(tryptophan 2,3-dioxygenase activity)|go:"GO:0005829"(cytosol)|go:"GO:0016597"(amino acid binding)|go:"GO:0019441"(tryptophan catabolic process to kynurenine)|go:"GO:0019442"(tryptophan catabolic process to acetyl-CoA)|go:"GO:0019825"(oxygen binding)|go:"GO:0020037"(heme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051289"(protein homotetramerization)|go:"GO:1904842"(response to nitroglycerin)|interpro:IPR004981(Tryptophan 2,3-dioxygenase)|interpro:IPR037217|mint:P48775|rcsb pdb:4PW8|rcsb pdb:5TI9|rcsb pdb:5TIA|rcsb pdb:6A4I|rcsb pdb:6PYY|rcsb pdb:6PYZ|rcsb pdb:6UD5|rcsb pdb:6VBN|reactome:R-HSA-71240|refseq:NP_005642.1|entrezgene/locuslink:6999(identity)	refseq:NP_010863.1|sgd:S000000777|ensemblfungi:YEL051W(gene)|ensemblfungi:YEL051W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0016471"(vacuolar proton-transporting V-type ATPase complex)|go:"GO:0033176"(proton-transporting V-type ATPase complex)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR002699(ATPase, V1/A1 complex, subunit D)|rcsb pdb:3J9T|rcsb pdb:3J9U|rcsb pdb:3J9V|rcsb pdb:4RND|rcsb pdb:5BW9|rcsb pdb:5D80|rcsb pdb:5VOX|rcsb pdb:5VOY|rcsb pdb:5VOZ|rcsb pdb:6O7V|rcsb pdb:6O7W|rcsb pdb:6O7X|reactome:R-SCE-1222556|reactome:R-SCE-6798695|reactome:R-SCE-77387|reactome:R-SCE-917977|reactome:R-SCE-9639288|dip:DIP-2959N|mint:P32610|sgd:YEL051W(identity)	-	-	crc64:FDE93E1FAF0AEC5B	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:S+cyc710I52nIFQWgKhXFul9QZw9606	rogid:rrwRno7lCnDeTNwawONkGwV8Hkg559292	intact-crc:BECBCCDE3B45373B|rigid:k/4RXew9tqL8bMsUlj6jyHMJQ30	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32610	uniprotkb:P19012	intact:EBI-20264|uniprotkb:D3DLJ9|ensemblfungi:YEL051W	intact:EBI-739566|uniprotkb:Q53XV8|uniprotkb:Q9BUG4|uniprotkb:B3KQY1|uniprotkb:B3KRA2|uniprotkb:E0CX14|ensembl:ENSP00000254043|ensembl:ENSP00000377546	psi-mi:vatd_yeast(display_long)|uniprotkb:VMA8(gene name)|psi-mi:VMA8(display_short)|uniprotkb:YEL051W(locus name)|uniprotkb:SYGP-ORF11(orf name)|uniprotkb:Vacuolar proton pump subunit D(gene name synonym)	psi-mi:k1c15_human(display_long)|uniprotkb:KRT15(gene name)|psi-mi:KRT15(display_short)|uniprotkb:KRTB(gene name synonym)|uniprotkb:Cytokeratin-15(gene name synonym)|uniprotkb:Keratin-15(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11555956|imex:IM-24995-4463	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010863.1|sgd:S000000777|ensemblfungi:YEL051W(gene)|ensemblfungi:YEL051W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0016471"(vacuolar proton-transporting V-type ATPase complex)|go:"GO:0033176"(proton-transporting V-type ATPase complex)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR002699(ATPase, V1/A1 complex, subunit D)|rcsb pdb:3J9T|rcsb pdb:3J9U|rcsb pdb:3J9V|rcsb pdb:4RND|rcsb pdb:5BW9|rcsb pdb:5D80|rcsb pdb:5VOX|rcsb pdb:5VOY|rcsb pdb:5VOZ|rcsb pdb:6O7V|rcsb pdb:6O7W|rcsb pdb:6O7X|reactome:R-SCE-1222556|reactome:R-SCE-6798695|reactome:R-SCE-77387|reactome:R-SCE-917977|reactome:R-SCE-9639288|dip:DIP-2959N|mint:P32610|sgd:YEL051W(identity)	refseq:NP_002266.2|ensembl:ENSG00000171346(gene)|ensembl:ENST00000254043(transcript)|ensembl:ENST00000393976(transcript)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0008544"(epidermis development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097110"(scaffold protein binding)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR039008|mint:P19012|reactome:R-HSA-6805567|reactome:R-HSA-6809371|entrezgene/locuslink:3866(identity)	-	crc64:FDE93E1FAF0AEC5B	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:rrwRno7lCnDeTNwawONkGwV8Hkg559292	rogid:WrZQBYQvrWcfrR5ojWXrXp6spPE9606	intact-crc:D3321645D7673B28|rigid:xGHgIT8Lu5s5UtthxS5AsbS9L9E	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32902	uniprotkb:Q7Z6G3-2	intact:EBI-16248|ensemblfungi:YHL004W|uniprotkb:D3DKR0	intact:EBI-10172876|ensembl:ENSP00000457354|intact:EBI-14062040	psi-mi:rt04_yeast(display_long)|uniprotkb:MRP4(gene name)|psi-mi:MRP4(display_short)|uniprotkb:MRP4A(gene name synonym)|uniprotkb:Mitochondrial small ribosomal subunit protein uS2m(gene name synonym)|uniprotkb:YHL004W(locus name)	psi-mi:q7z6g3-2(display_long)|uniprotkb:EFCBP2(gene name synonym)|uniprotkb:Neuronal calcium-binding protein 2(gene name synonym)|uniprotkb:Synaptotagmin-interacting protein 2(gene name synonym)|uniprotkb:NECAB2(gene name)|psi-mi:NECAB2(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11556084|imex:IM-24995-4477	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YHL004W(gene)|ensemblfungi:YHL004W_mRNA(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR001865(Ribosomal protein S2)|interpro:IPR005706(Ribosomal protein S2, bacterial-type)|interpro:IPR018130|interpro:IPR023591|rcsb pdb:5MRC|rcsb pdb:5MRE|rcsb pdb:5MRF|refseq:NP_011859.1|sgd:S000000996|dip:DIP-5035N|mint:P32902|sgd:YHL004W(identity)	ensembl:ENSG00000103154(gene)|ensembl:ENST00000565691(transcript)|uniprotkb:Q7Z6G3-2(isoform-parent)|intact:EBI-950070(isoform-parent)|entrezgene/locuslink:54550(identity)	-	crc64:81A1CB33134BC559	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:BlL3W6HUN+uAKF/AxwlV1zT5YZQ559292	rogid:4S7oIx6h+mKzV3EPxqcfMNqaNko9606	intact-crc:250D50E7B228E26F|rigid:m58Zj9qZ8WkdvEdqLw8LDRMDctM	false	-	sufficient binding region:65-303	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
intact:EBI-11525577	uniprotkb:P32902	-	intact:EBI-16248|ensemblfungi:YHL004W|uniprotkb:D3DKR0	psi-mi:pde4dip(display_short)|psi-mi:EBI-11525577(display_long)	psi-mi:rt04_yeast(display_long)|uniprotkb:MRP4(gene name)|psi-mi:MRP4(display_short)|uniprotkb:MRP4A(gene name synonym)|uniprotkb:Mitochondrial small ribosomal subunit protein uS2m(gene name synonym)|uniprotkb:YHL004W(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11556075|imex:IM-24995-4476	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	entrezgene/locuslink:9659(identity)	ensemblfungi:YHL004W(gene)|ensemblfungi:YHL004W_mRNA(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR001865(Ribosomal protein S2)|interpro:IPR005706(Ribosomal protein S2, bacterial-type)|interpro:IPR018130|interpro:IPR023591|rcsb pdb:5MRC|rcsb pdb:5MRE|rcsb pdb:5MRF|refseq:NP_011859.1|sgd:S000000996|dip:DIP-5035N|mint:P32902|sgd:YHL004W(identity)	-	no-uniprot-update:	crc64:81A1CB33134BC559	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:1FG5rtwoLqpyiNu81cqSpFdaXDY9606	rogid:BlL3W6HUN+uAKF/AxwlV1zT5YZQ559292	intact-crc:9327DEF0C51FFB06|rigid:RLNKJwoWVyDqVcuX5iOyxTOx78U	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q14558	uniprotkb:P32895	intact:EBI-724449|uniprotkb:Q96H06|uniprotkb:B2R6M4	intact:EBI-9869|uniprotkb:D6VX20|ensemblfungi:YKL181W	psi-mi:kpra_human(display_long)|uniprotkb:39 kDa phosphoribosypyrophosphate synthase-associated protein(gene name synonym)|uniprotkb:PRPSAP1(gene name)|psi-mi:PRPSAP1(display_short)	psi-mi:kpr1_yeast(display_long)|uniprotkb:PPS1(gene name synonym)|uniprotkb:PRP1(gene name synonym)|uniprotkb:PRPS(gene name synonym)|uniprotkb:PRPS1(gene name synonym)|uniprotkb:YKL181W(locus name)|uniprotkb:PRS1(gene name)|psi-mi:PRS1(display_short)|uniprotkb:Phosphoribosyl pyrophosphate synthase 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11556066|imex:IM-24995-4475	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002757.2|interpro:IPR005946(Phosphoribosyl pyrophosphokinase)|rcsb pdb:2C4K|go:"GO:0000287"(magnesium ion binding)|go:"GO:0002189"(ribose phosphate diphosphokinase complex)|go:"GO:0004749"(ribose phosphate diphosphokinase activity)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006015"(5-phosphoribose 1-diphosphate biosynthetic process)|go:"GO:0006139"(nucleobase-containing compound metabolic process)|go:"GO:0006164"(purine nucleotide biosynthetic process)|go:"GO:0042802"(identical protein binding)|interpro:IPR029057|interpro:IPR029099|entrezgene/locuslink:5635(identity)	refseq:NP_012740.1|sgd:S000001664|ensemblfungi:YKL181W(gene)|ensemblfungi:YKL181W_mRNA(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0002189"(ribose phosphate diphosphokinase complex)|go:"GO:0004749"(ribose phosphate diphosphokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006015"(5-phosphoribose 1-diphosphate biosynthetic process)|go:"GO:0006164"(purine nucleotide biosynthetic process)|go:"GO:0009116"(nucleoside metabolic process)|go:"GO:0009156"(ribonucleoside monophosphate biosynthetic process)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016301"(kinase activity)|go:"GO:0031505"(fungal-type cell wall organization)|interpro:IPR000836(Phosphoribosyltransferase)|interpro:IPR000842(Phosphoribosyl pyrophosphate synthetase, conserved site)|interpro:IPR005946(Phosphoribosyl pyrophosphokinase)|interpro:IPR029057|interpro:IPR029099|reactome:R-SCE-73843|dip:DIP-4857N|mint:P32895|sgd:YKL181W(identity)	-	-	crc64:F3E93ACB25E703FF	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:7kFJX6q/3EcGnRNgAOImlr93Xys9606	rogid:Ea45pOje4sjYrrU7ze4Af443yDk559292	intact-crc:6B6D743133E4091B|rigid:qvyrZ/jsfWNgyC6izWzv5pYzHE4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P60891	uniprotkb:P32895	intact:EBI-749195|uniprotkb:P09329|uniprotkb:B2R6T7|uniprotkb:B1ALA8|uniprotkb:B4DNL6|uniprotkb:D3DUX6|ensembl:ENSP00000361512	intact:EBI-9869|uniprotkb:D6VX20|ensemblfungi:YKL181W	psi-mi:prps1_human(display_long)|uniprotkb:Phosphoribosyl pyrophosphate synthase I(gene name synonym)|uniprotkb:PRPS1(gene name)|psi-mi:PRPS1(display_short)|uniprotkb:PPRibP(gene name synonym)	psi-mi:kpr1_yeast(display_long)|uniprotkb:PPS1(gene name synonym)|uniprotkb:PRP1(gene name synonym)|uniprotkb:PRPS(gene name synonym)|uniprotkb:PRPS1(gene name synonym)|uniprotkb:YKL181W(locus name)|uniprotkb:PRS1(gene name)|psi-mi:PRS1(display_short)|uniprotkb:Phosphoribosyl pyrophosphate synthase 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11556057|imex:IM-24995-4474	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001191331.1|refseq:NP_002755.1|ensembl:ENSG00000147224(gene)|ensembl:ENST00000372435(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0002189"(ribose phosphate diphosphokinase complex)|go:"GO:0004749"(ribose phosphate diphosphokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006015"(5-phosphoribose 1-diphosphate biosynthetic process)|go:"GO:0006164"(purine nucleotide biosynthetic process)|go:"GO:0006221"(pyrimidine nucleotide biosynthetic process)|go:"GO:0007399"(nervous system development)|go:"GO:0009116"(nucleoside metabolic process)|go:"GO:0009156"(ribonucleoside monophosphate biosynthetic process)|go:"GO:0016301"(kinase activity)|go:"GO:0034418"(urate biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046101"(hypoxanthine biosynthetic process)|interpro:IPR000836(Phosphoribosyltransferase)|interpro:IPR000842(Phosphoribosyl pyrophosphate synthetase, conserved site)|interpro:IPR005946(Phosphoribosyl pyrophosphokinase)|go:"GO:0006144"(purine nucleobase metabolic process)|interpro:IPR029057|interpro:IPR029099|interpro:IPR037515|rcsb pdb:2H06|rcsb pdb:2H07|rcsb pdb:2H08|rcsb pdb:2HCR|rcsb pdb:3EFH|rcsb pdb:3S5J|rcsb pdb:4F8E|rcsb pdb:4LYG|rcsb pdb:4LZN|rcsb pdb:4LZO|rcsb pdb:4M0P|rcsb pdb:4M0U|reactome:R-HSA-73843|dip:DIP-61999N|entrezgene/locuslink:5631(identity)	refseq:NP_012740.1|sgd:S000001664|ensemblfungi:YKL181W(gene)|ensemblfungi:YKL181W_mRNA(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0002189"(ribose phosphate diphosphokinase complex)|go:"GO:0004749"(ribose phosphate diphosphokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006015"(5-phosphoribose 1-diphosphate biosynthetic process)|go:"GO:0006164"(purine nucleotide biosynthetic process)|go:"GO:0009116"(nucleoside metabolic process)|go:"GO:0009156"(ribonucleoside monophosphate biosynthetic process)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016301"(kinase activity)|go:"GO:0031505"(fungal-type cell wall organization)|interpro:IPR000836(Phosphoribosyltransferase)|interpro:IPR000842(Phosphoribosyl pyrophosphate synthetase, conserved site)|interpro:IPR005946(Phosphoribosyl pyrophosphokinase)|interpro:IPR029057|interpro:IPR029099|reactome:R-SCE-73843|dip:DIP-4857N|mint:P32895|sgd:YKL181W(identity)	-	-	crc64:F3E93ACB25E703FF	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:+Hih2M7JLTsjEglauBlPj182h9M9606	rogid:Ea45pOje4sjYrrU7ze4Af443yDk559292	intact-crc:802AC815E60AE71A|rigid:3TY8kxFwrUo6RAg2bNdsrGenDxc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8N5R6	uniprotkb:P32844	intact:EBI-740841|intact:EBI-953781|uniprotkb:B3KQ49|uniprotkb:A8K3U4|uniprotkb:A8MPQ6|uniprotkb:A8MV61|uniprotkb:A8MVU9|uniprotkb:Q9H5Q6|uniprotkb:Q8TAX6|intact:EBI-2320546|intact:EBI-11522976	intact:EBI-16874|uniprotkb:D6VVL6|ensemblfungi:YIL068C	psi-mi:ccd33_human(display_long)|uniprotkb:CCDC33(gene name)|psi-mi:CCDC33(display_short)|uniprotkb:Cancer/testis antigen 61(gene name synonym)	psi-mi:sec6_yeast(display_long)|uniprotkb:YIL068C(locus name)|uniprotkb:SEC6(gene name)|psi-mi:SEC6(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11556048|imex:IM-24995-4473	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_079331.3|interpro:IPR000008(C2 calcium-dependent membrane targeting)|go:"GO:0005777"(peroxisome)|refseq:NP_001274110.1|refseq:NP_877592.2|mint:Q8N5R6|interpro:IPR035892|interpro:IPR039889|entrezgene/locuslink:80125(identity)	refseq:NP_012196.1|sgd:S000001330|ensemblfungi:YIL068C(gene)|ensemblfungi:YIL068C_mRNA(transcript)|go:"GO:0000145"(exocyst)|go:"GO:0000149"(SNARE binding)|go:"GO:0005628"(prospore membrane)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0015031"(protein transport)|go:"GO:0035544"(negative regulation of SNARE complex assembly)|go:"GO:0043332"(mating projection tip)|go:"GO:0051601"(exocyst localization)|go:"GO:0090522"(vesicle tethering involved in exocytosis)|interpro:IPR010326(Exocyst complex component Sec6)|interpro:IPR042532|rcsb pdb:2FJI|rcsb pdb:5YFP|rcsb pdb:6VKL|reactome:R-SCE-264876|dip:DIP-5649N|mint:P32844|sgd:YIL068C(identity)	-	-	crc64:2B09BBBE15389239	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2021/11/30	rogid:eEIn7pQyfdHWx8TeLJpYy0i/gww9606	rogid:SJtUIHyBTy38oPOc0h4D3Anipvc559292	intact-crc:DD3822C32A2A83DB|rigid:x4nnJ1Ba4hXL5Wbd4a9rc+M/1as	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32831	uniprotkb:Q15427	intact:EBI-12002|ensemblfungi:YBR212W|uniprotkb:D6VQK8	intact:EBI-348469|ensembl:ENSP00000271628|intact:EBI-1047735|uniprotkb:Q5SZ63	psi-mi:ngr1_yeast(display_long)|uniprotkb:NGR1(gene name)|psi-mi:NGR1(display_short)|uniprotkb:RBP1(gene name synonym)|uniprotkb:YBR212W(locus name)|uniprotkb:YBR1459(orf name)|uniprotkb:RNA-binding protein RBP1(gene name synonym)	psi-mi:sf3b4_human(display_long)|uniprotkb:SF3B4(gene name)|psi-mi:SF3B4(display_short)|uniprotkb:SAP49(gene name synonym)|uniprotkb:Spliceosome-associated protein 49(gene name synonym)|uniprotkb:Pre-mRNA-splicing factor SF3b 49 kDa subunit(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11556039|imex:IM-24995-4472	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YBR212W(gene)|ensemblfungi:YBR212W_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|refseq:NP_009771.3|sgd:S000000416|mint:P32831|dip:DIP-5160N|sgd:YBR212W(identity)	refseq:NP_005841.1|ensembl:ENSG00000143368(gene)|ensembl:ENST00000271628(transcript)|rcsb pdb:6QX9|rcsb pdb:6Y53|rcsb pdb:6Y5Q|rcsb pdb:7ABG|rcsb pdb:7ABH|rcsb pdb:7ABI|rcsb pdb:7DVQ|reactome:R-HSA-72163|reactome:R-HSA-72165|rcsb pdb:6AHD|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:1990935"(splicing factor binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034158|go:"GO:0000375"(RNA splicing, via transesterification reactions)|interpro:IPR034159|interpro:IPR035979|mint:Q15427|rcsb pdb:1X5T|rcsb pdb:5GVQ|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|entrezgene/locuslink:10262(identity)	-	crc64:12F64EC4C5716750	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:MCNbYrmWkUp7dAyKpebSKsIzOxA559292	rogid:Jgy6WmBFKkphpZLLte2GgsagUVI9606	intact-crc:913677A8AEC3B1B3|rigid:WSu9Xoaj+gpfen6jYmc5WJVxJlk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32831	uniprotkb:Q08379	intact:EBI-12002|ensemblfungi:YBR212W|uniprotkb:D6VQK8	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	psi-mi:ngr1_yeast(display_long)|uniprotkb:NGR1(gene name)|psi-mi:NGR1(display_short)|uniprotkb:RBP1(gene name synonym)|uniprotkb:YBR212W(locus name)|uniprotkb:YBR1459(orf name)|uniprotkb:RNA-binding protein RBP1(gene name synonym)	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11556028|imex:IM-24995-4471	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YBR212W(gene)|ensemblfungi:YBR212W_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|refseq:NP_009771.3|sgd:S000000416|mint:P32831|dip:DIP-5160N|sgd:YBR212W(identity)	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N|entrezgene/locuslink:2801(identity)	-	crc64:12F64EC4C5716750	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2017/05/26	rogid:MCNbYrmWkUp7dAyKpebSKsIzOxA559292	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	intact-crc:F9E3FC71998BEE6A|rigid:v3TpDbdeJVmyOr+hoErXJ5VXAF0	false	-	sufficient binding region:383-1002	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9H190	uniprotkb:P32796	intact:EBI-742426|ensembl:ENSP00000371233|uniprotkb:O95892|uniprotkb:Q5W0X1|uniprotkb:Q9BZ42|uniprotkb:Q9H567|uniprotkb:Q9NRY8|intact:EBI-28983470|ensembl:ENSP00000342935|ensembl:ENSP00000354013	intact:EBI-3935|uniprotkb:D6VZD3|ensemblfungi:YML042W	psi-mi:sdcb2_human(display_long)|uniprotkb:Similar to TACIP18(gene name synonym)|uniprotkb:SDCBP2(gene name)|psi-mi:SDCBP2(display_short)|uniprotkb:SITAC18(gene name synonym)|uniprotkb:Syndecan-binding protein 2(gene name synonym)	psi-mi:cacp_yeast(display_long)|uniprotkb:CAT2(gene name)|psi-mi:CAT2(display_short)|uniprotkb:CAT(gene name synonym)|uniprotkb:YCAT(gene name synonym)|uniprotkb:YML042W(locus name)|uniprotkb:YM8054.01(orf name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11556019|imex:IM-24995-4470	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001186713.1|refseq:NP_056500.2|refseq:NP_536737.3|ensembl:ENSP00000342935|ensembl:ENSP00000354013|ensembl:ENST00000381808|ensembl:ENSP00000371229|ensembl:ENSP00000371233|ensembl:ENSG00000125775(gene)|ensembl:ENST00000360779(transcript)|ensembl:ENST00000381812(transcript)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007399"(nervous system development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016607"(nuclear speck)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046907"(intracellular transport)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036034|interpro:IPR041489|ensembl:ENST00000339987(transcript)|entrezgene/locuslink:27111(identity)	refseq:NP_013670.1|sgd:S000004506|dip:DIP-2476N|reactome:R-SCE-1483191|reactome:R-SCE-264642|reactome:R-SCE-389887|reactome:R-SCE-9033241|ensemblfungi:YML042W(gene)|ensemblfungi:YML042W_mRNA(transcript)|go:"GO:0004092"(carnitine O-acetyltransferase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005777"(peroxisome)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0009437"(carnitine metabolic process)|interpro:IPR000542(Acyltransferase ChoActase/COT/CPT)|interpro:IPR023213|interpro:IPR039551|interpro:IPR042231|sgd:YML042W(identity)	-	-	crc64:C707BAC7ECB4D095	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:vlEtVZkwLTte5PJ4i8ce+SwE/4Y9606	rogid:2UCscm7QlYT+CY3gtU/Wg37C/+Y559292	intact-crc:ED5C3D7218DB0766|rigid:GebY+wTkfNrK55hJdHdAHIewoxc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32902	uniprotkb:Q8IYF3-3	intact:EBI-16248|ensemblfungi:YHL004W|uniprotkb:D3DKR0	intact:EBI-11523345|ensembl:ENSP00000363453	psi-mi:rt04_yeast(display_long)|uniprotkb:MRP4(gene name)|psi-mi:MRP4(display_short)|uniprotkb:MRP4A(gene name synonym)|uniprotkb:Mitochondrial small ribosomal subunit protein uS2m(gene name synonym)|uniprotkb:YHL004W(locus name)	psi-mi:q8iyf3-3(display_long)|uniprotkb:TEX11(gene name)|psi-mi:TEX11(display_short)|uniprotkb:Protein ZIP4 homolog(gene name synonym)|uniprotkb:ZIP4(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11556167|imex:IM-24995-4486	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YHL004W(gene)|ensemblfungi:YHL004W_mRNA(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR001865(Ribosomal protein S2)|interpro:IPR005706(Ribosomal protein S2, bacterial-type)|interpro:IPR018130|interpro:IPR023591|rcsb pdb:5MRC|rcsb pdb:5MRE|rcsb pdb:5MRF|refseq:NP_011859.1|sgd:S000000996|dip:DIP-5035N|mint:P32902|sgd:YHL004W(identity)	ensembl:ENSG00000120498(gene)|ensembl:ENST00000374333(transcript)|intact:EBI-742397(isoform-parent)|uniprotkb:Q8IYF3-3(isoform-parent)|entrezgene/locuslink:56159(identity)	-	crc64:81A1CB33134BC559	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:BlL3W6HUN+uAKF/AxwlV1zT5YZQ559292	rogid:PUAMFmnm5ZV2rnJ1rhm9ZeRCixg9606	intact-crc:83BF6CEC024FB66D|rigid:5O6jZs2BB4nz3YQQSmrfCo54JsY	false	-	sufficient binding region:9-925	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q5T124-6	uniprotkb:P32902	intact:EBI-11524408	intact:EBI-16248|ensemblfungi:YHL004W|uniprotkb:D3DKR0	psi-mi:q5t124-6(display_long)|uniprotkb:UBXN11(gene name)|psi-mi:UBXN11(display_short)|uniprotkb:Colorectal tumor-associated antigen COA-1(gene name synonym)|uniprotkb:SOC(gene name synonym)|uniprotkb:Socius(gene name synonym)|uniprotkb:UBX domain-containing protein 5(gene name synonym)|uniprotkb:UBXD5(gene name synonym)|uniprotkb:PP2243(orf name)	psi-mi:rt04_yeast(display_long)|uniprotkb:MRP4(gene name)|psi-mi:MRP4(display_short)|uniprotkb:MRP4A(gene name synonym)|uniprotkb:Mitochondrial small ribosomal subunit protein uS2m(gene name synonym)|uniprotkb:YHL004W(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11556158|imex:IM-24995-4485	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-746004(isoform-parent)|uniprotkb:Q5T124-6(isoform-parent)|entrezgene/locuslink:91544(identity)	ensemblfungi:YHL004W(gene)|ensemblfungi:YHL004W_mRNA(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR001865(Ribosomal protein S2)|interpro:IPR005706(Ribosomal protein S2, bacterial-type)|interpro:IPR018130|interpro:IPR023591|rcsb pdb:5MRC|rcsb pdb:5MRE|rcsb pdb:5MRF|refseq:NP_011859.1|sgd:S000000996|dip:DIP-5035N|mint:P32902|sgd:YHL004W(identity)	-	-	crc64:81A1CB33134BC559	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:1YSjG/p2ihcjl4P8KdPCaX2HxiY9606	rogid:BlL3W6HUN+uAKF/AxwlV1zT5YZQ559292	intact-crc:A310D26D7A2AE1CC|rigid:Rn3lxpxa/3W/L2hcoFjM/QSt1G4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q5JR59-3	uniprotkb:P32902	intact:EBI-11522433|ensembl:ENSP00000370186	intact:EBI-16248|ensemblfungi:YHL004W|uniprotkb:D3DKR0	psi-mi:q5jr59-3(display_long)|uniprotkb:MTUS2(gene name)|psi-mi:MTUS2(display_short)|uniprotkb:CAZIP(gene name synonym)|uniprotkb:Cardiac zipper protein(gene name synonym)|uniprotkb:KIAA0774(gene name synonym)|uniprotkb:Microtubule plus-end tracking protein TIP150(gene name synonym)|uniprotkb:TIP150(gene name synonym)	psi-mi:rt04_yeast(display_long)|uniprotkb:MRP4(gene name)|psi-mi:MRP4(display_short)|uniprotkb:MRP4A(gene name synonym)|uniprotkb:Mitochondrial small ribosomal subunit protein uS2m(gene name synonym)|uniprotkb:YHL004W(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11556149|imex:IM-24995-4484	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000132938(gene)|ensembl:ENST00000380808(transcript)|intact:EBI-742948(isoform-parent)|uniprotkb:Q5JR59-3(isoform-parent)|entrezgene/locuslink:23281(identity)	ensemblfungi:YHL004W(gene)|ensemblfungi:YHL004W_mRNA(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR001865(Ribosomal protein S2)|interpro:IPR005706(Ribosomal protein S2, bacterial-type)|interpro:IPR018130|interpro:IPR023591|rcsb pdb:5MRC|rcsb pdb:5MRE|rcsb pdb:5MRF|refseq:NP_011859.1|sgd:S000000996|dip:DIP-5035N|mint:P32902|sgd:YHL004W(identity)	-	isoform-comment:No experimental confirmation available.	crc64:81A1CB33134BC559	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:npId9tC7VoLN/jteoBiRbSYChPs9606	rogid:BlL3W6HUN+uAKF/AxwlV1zT5YZQ559292	intact-crc:74B46758B0B99955|rigid:SUqmciFNzecgze196/COIEQtPY0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32902	uniprotkb:Q13137	intact:EBI-16248|ensemblfungi:YHL004W|uniprotkb:D3DKR0	intact:EBI-739580|uniprotkb:B4DDC4|uniprotkb:E7ENK0|uniprotkb:Q53FQ5|uniprotkb:Q53HB5|uniprotkb:Q6IBN9|uniprotkb:Q9BTF7|uniprotkb:B2RBT0|ensembl:ENSP00000258947|uniprotkb:B4E0C0|uniprotkb:E7ETP5|uniprotkb:B4DDT4|uniprotkb:B4DP36|uniprotkb:E9PBE5	psi-mi:rt04_yeast(display_long)|uniprotkb:MRP4(gene name)|psi-mi:MRP4(display_short)|uniprotkb:MRP4A(gene name synonym)|uniprotkb:Mitochondrial small ribosomal subunit protein uS2m(gene name synonym)|uniprotkb:YHL004W(locus name)	psi-mi:caco2_human(display_long)|uniprotkb:CALCOCO2(gene name)|psi-mi:CALCOCO2(display_short)|uniprotkb:NDP52(gene name synonym)|uniprotkb:Nuclear domain 10 protein NDP52(gene name synonym)|uniprotkb:Antigen nuclear dot 52 kDa protein(gene name synonym)|uniprotkb:Nuclear dot protein 52(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11556140|imex:IM-24995-4483	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YHL004W(gene)|ensemblfungi:YHL004W_mRNA(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR001865(Ribosomal protein S2)|interpro:IPR005706(Ribosomal protein S2, bacterial-type)|interpro:IPR018130|interpro:IPR023591|rcsb pdb:5MRC|rcsb pdb:5MRE|rcsb pdb:5MRF|refseq:NP_011859.1|sgd:S000000996|dip:DIP-5035N|mint:P32902|sgd:YHL004W(identity)	refseq:NP_001248319.1|refseq:NP_001248320.1|refseq:NP_001248322.1|refseq:NP_005822.1|ensembl:ENSG00000136436(gene)|ensembl:ENST00000258947(transcript)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016032"(viral process)|go:"GO:0016605"(PML body)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0098792"(xenophagy)|go:"GO:1901098"(positive regulation of autophagosome maturation)|interpro:IPR041611|interpro:IPR041641|mint:Q13137|rcsb pdb:2MXP|rcsb pdb:3VVV|rcsb pdb:3VVW|rcsb pdb:4GXL|rcsb pdb:4HAN|rcsb pdb:4XKL|rcsb pdb:5AAQ|rcsb pdb:5Z7A|rcsb pdb:5Z7L|refseq:NP_001248324.1|dip:DIP-57534N|entrezgene/locuslink:10241(identity)	-	crc64:81A1CB33134BC559	crc64:609B121DA1A9DCB8	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:BlL3W6HUN+uAKF/AxwlV1zT5YZQ559292	rogid:N/GPJUGBK+Dh5Cg+csmafphuo9M9606	intact-crc:349894EB2FCE4191|rigid:4ZnZLADDPmSwFQZcdVxBb3YFxqI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P43361	uniprotkb:P32902	intact:EBI-10182930|uniprotkb:Q9BUN9|intact:EBI-28989087|ensembl:ENSP00000286482|ensembl:ENSP00000438293|ensembl:ENSP00000443776	intact:EBI-16248|ensemblfungi:YHL004W|uniprotkb:D3DKR0	psi-mi:maga8_human(display_long)|uniprotkb:MAGEA8(gene name)|psi-mi:MAGEA8(display_short)|uniprotkb:Cancer/testis antigen 1.8(gene name synonym)|uniprotkb:MAGE-8 antigen(gene name synonym)|uniprotkb:MAGE8(gene name synonym)	psi-mi:rt04_yeast(display_long)|uniprotkb:MRP4(gene name)|psi-mi:MRP4(display_short)|uniprotkb:MRP4A(gene name synonym)|uniprotkb:Mitochondrial small ribosomal subunit protein uS2m(gene name synonym)|uniprotkb:YHL004W(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11556131|imex:IM-24995-4482	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001159872.1|refseq:NP_001159873.1|refseq:NP_005355.2|refseq:XP_016885009.1|ensembl:ENSP00000286482|ensembl:ENSP00000438293|ensembl:ENSP00000443776|ensembl:ENSG00000156009(gene)|ensembl:ENST00000286482(transcript)|ensembl:ENST00000535454(transcript)|ensembl:ENST00000542674(transcript)|interpro:IPR002190(MAGE protein)|interpro:IPR021072|interpro:IPR030095|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|entrezgene/locuslink:4107(identity)	ensemblfungi:YHL004W(gene)|ensemblfungi:YHL004W_mRNA(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR001865(Ribosomal protein S2)|interpro:IPR005706(Ribosomal protein S2, bacterial-type)|interpro:IPR018130|interpro:IPR023591|rcsb pdb:5MRC|rcsb pdb:5MRE|rcsb pdb:5MRF|refseq:NP_011859.1|sgd:S000000996|dip:DIP-5035N|mint:P32902|sgd:YHL004W(identity)	-	-	crc64:81A1CB33134BC559	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Qz29eM5nzFfUZl/DBtBcdhGQBNE9606	rogid:BlL3W6HUN+uAKF/AxwlV1zT5YZQ559292	intact-crc:624365FE32DC7F28|rigid:VTbvHt8oLrIEYWwXe7e88GF4gGE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32902	uniprotkb:P36406	intact:EBI-16248|ensemblfungi:YHL004W|uniprotkb:D3DKR0	intact:EBI-740098|uniprotkb:Q9BZY4|uniprotkb:Q9BZY5|ensembl:ENSP00000231524	psi-mi:rt04_yeast(display_long)|uniprotkb:MRP4(gene name)|psi-mi:MRP4(display_short)|uniprotkb:MRP4A(gene name synonym)|uniprotkb:Mitochondrial small ribosomal subunit protein uS2m(gene name synonym)|uniprotkb:YHL004W(locus name)	psi-mi:tri23_human(display_long)|uniprotkb:TRIM23(gene name)|psi-mi:TRIM23(display_short)|uniprotkb:ARD1(gene name synonym)|uniprotkb:ARFD1(gene name synonym)|uniprotkb:RNF46(gene name synonym)|uniprotkb:ADP-ribosylation factor domain-containing protein 1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 23(gene name synonym)|uniprotkb:RING finger protein 46(gene name synonym)|uniprotkb:GTP-binding protein ARD-1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM23(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11556122|imex:IM-24995-4481	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YHL004W(gene)|ensemblfungi:YHL004W_mRNA(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR001865(Ribosomal protein S2)|interpro:IPR005706(Ribosomal protein S2, bacterial-type)|interpro:IPR018130|interpro:IPR023591|rcsb pdb:5MRC|rcsb pdb:5MRE|rcsb pdb:5MRF|refseq:NP_011859.1|sgd:S000000996|dip:DIP-5035N|mint:P32902|sgd:YHL004W(identity)	refseq:NP_001647.1|refseq:NP_150230.1|refseq:NP_150231.1|refseq:XP_016864933.1|ensembl:ENSG00000113595(gene)|ensembl:ENST00000231524(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019003"(GDP binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR017907|interpro:IPR027417|mint:P36406|rcsb pdb:5VZV|rcsb pdb:5VZW|entrezgene/locuslink:373(identity)	-	crc64:81A1CB33134BC559	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:BlL3W6HUN+uAKF/AxwlV1zT5YZQ559292	rogid:skGAO7nm9YvqJGWF6fzjtn5CWuc9606	intact-crc:C3656543FFA08CAE|rigid:B+YCiMtTsROETnJFJlOLGrc0lvM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32902	uniprotkb:P13196	intact:EBI-16248|ensemblfungi:YHL004W|uniprotkb:D3DKR0	intact:EBI-3905054|ensembl:ENSP00000309259|ensembl:ENSP00000378416|ensembl:ENSP00000417719|ensembl:ENSP00000418779	psi-mi:rt04_yeast(display_long)|uniprotkb:MRP4(gene name)|psi-mi:MRP4(display_short)|uniprotkb:MRP4A(gene name synonym)|uniprotkb:Mitochondrial small ribosomal subunit protein uS2m(gene name synonym)|uniprotkb:YHL004W(locus name)	psi-mi:hem1_human(display_long)|uniprotkb:ALAS1(gene name)|psi-mi:ALAS1(display_short)|uniprotkb:ALAS3(gene name synonym)|uniprotkb:ALASH(gene name synonym)|uniprotkb:5-aminolevulinic acid synthase 1(gene name synonym)|uniprotkb:Delta-ALA synthase 1(gene name synonym)|uniprotkb:Delta-aminolevulinate synthase 1(gene name synonym)|uniprotkb:OK/SW-cl.121(orf name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11556113|imex:IM-24995-4480	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YHL004W(gene)|ensemblfungi:YHL004W_mRNA(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR001865(Ribosomal protein S2)|interpro:IPR005706(Ribosomal protein S2, bacterial-type)|interpro:IPR018130|interpro:IPR023591|rcsb pdb:5MRC|rcsb pdb:5MRE|rcsb pdb:5MRF|refseq:NP_011859.1|sgd:S000000996|dip:DIP-5035N|mint:P32902|sgd:YHL004W(identity)	refseq:NP_001291372.1|refseq:NP_001291373.1|refseq:NP_000679.1|refseq:NP_954635.1|go:"GO:0006783"(heme biosynthetic process)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0042541"(hemoglobin biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0048821"(erythrocyte development)|ensembl:ENSG00000023330(gene)|ensembl:ENST00000310271(transcript)|ensembl:ENST00000394965(transcript)|ensembl:ENST00000469224(transcript)|ensembl:ENST00000484952(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0003870"(5-aminolevulinate synthase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|interpro:IPR001917(Aminotransferase, class-II, pyridoxal-phosphate binding site)|interpro:IPR004839(Aminotransferase, class I and II)|interpro:IPR010961(Tetrapyrrole biosynthesis, 5-aminolevulinic acid synthase)|interpro:IPR015118(5-aminolevulinate synthase presequence)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|mint:P13196|reactome:R-HSA-189451|reactome:R-HSA-1989781|reactome:R-HSA-2151201|go:"GO:0006782"(protoporphyrinogen IX biosynthetic process)|entrezgene/locuslink:211(identity)	-	crc64:81A1CB33134BC559	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:BlL3W6HUN+uAKF/AxwlV1zT5YZQ559292	rogid:HFjJ6zrRF9UYD7LMB6A3CcxcS7c9606	intact-crc:75A802278A1D5A45|rigid:hNk4Ti++B/6J9ajZ8u5eL5h10cY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32902	uniprotkb:O95751	intact:EBI-16248|ensemblfungi:YHL004W|uniprotkb:D3DKR0	intact:EBI-740738|ensembl:ENSP00000359557|uniprotkb:Q6IAR6	psi-mi:rt04_yeast(display_long)|uniprotkb:MRP4(gene name)|psi-mi:MRP4(display_short)|uniprotkb:MRP4A(gene name synonym)|uniprotkb:Mitochondrial small ribosomal subunit protein uS2m(gene name synonym)|uniprotkb:YHL004W(locus name)	psi-mi:ldoc1_human(display_long)|uniprotkb:Leucine zipper protein down-regulated in cancer cells(gene name synonym)|uniprotkb:LDOC1(gene name)|psi-mi:LDOC1(display_short)|uniprotkb:BCUR1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11556104|imex:IM-24995-4479	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YHL004W(gene)|ensemblfungi:YHL004W_mRNA(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR001865(Ribosomal protein S2)|interpro:IPR005706(Ribosomal protein S2, bacterial-type)|interpro:IPR018130|interpro:IPR023591|rcsb pdb:5MRC|rcsb pdb:5MRE|rcsb pdb:5MRF|refseq:NP_011859.1|sgd:S000000996|dip:DIP-5035N|mint:P32902|sgd:YHL004W(identity)	refseq:NP_036449.1|ensembl:ENSG00000182195(gene)|ensembl:ENST00000370526(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071225"(cellular response to muramyl dipeptide)|interpro:IPR032549|interpro:IPR032567|entrezgene/locuslink:23641(identity)	-	crc64:81A1CB33134BC559	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:BlL3W6HUN+uAKF/AxwlV1zT5YZQ559292	rogid:Ediu0oNiZ/+YVY8l3fNdgP5A+v09606	intact-crc:C4DEC69D28EC538A|rigid:3j66pJ42LxFcWILS+fD3GiJbTE4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32902	uniprotkb:O95273	intact:EBI-16248|ensemblfungi:YHL004W|uniprotkb:D3DKR0	intact:EBI-748961|uniprotkb:A8K3Q0|uniprotkb:A8K3U2|uniprotkb:Q6ZQN9|uniprotkb:Q7Z519|uniprotkb:Q8NBS7|uniprotkb:Q8NBY2|uniprotkb:Q9NS19|uniprotkb:Q9NYH3|uniprotkb:Q9UHX9|ensembl:ENSP00000300213	psi-mi:rt04_yeast(display_long)|uniprotkb:MRP4(gene name)|psi-mi:MRP4(display_short)|uniprotkb:MRP4A(gene name synonym)|uniprotkb:Mitochondrial small ribosomal subunit protein uS2m(gene name synonym)|uniprotkb:YHL004W(locus name)	psi-mi:ccdb1_human(display_long)|uniprotkb:Grap2 and cyclin-D-interacting protein(gene name synonym)|uniprotkb:Human homolog of Maid(gene name synonym)|uniprotkb:CCNDBP1(gene name)|psi-mi:CCNDBP1(display_short)|uniprotkb:DIP1(gene name synonym)|uniprotkb:GCIP(gene name synonym)|uniprotkb:HHM(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11556095|imex:IM-24995-4478	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YHL004W(gene)|ensemblfungi:YHL004W_mRNA(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR001865(Ribosomal protein S2)|interpro:IPR005706(Ribosomal protein S2, bacterial-type)|interpro:IPR018130|interpro:IPR023591|rcsb pdb:5MRC|rcsb pdb:5MRE|rcsb pdb:5MRF|refseq:NP_011859.1|sgd:S000000996|dip:DIP-5035N|mint:P32902|sgd:YHL004W(identity)	refseq:NP_036274.3|ensembl:ENSG00000166946(gene)|ensembl:ENST00000300213(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0016604"(nuclear body)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR026907|mint:O95273|rcsb pdb:3AY5|entrezgene/locuslink:23582(identity)	-	crc64:81A1CB33134BC559	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:BlL3W6HUN+uAKF/AxwlV1zT5YZQ559292	rogid:Vi9aoFc+Mov6P3X6KGmsTxXqxvM9606	intact-crc:9B73A200B88AEBA3|rigid:BDD/Zudt6reIXIk4+QnpoexF8Bc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32902	uniprotkb:Q96KN7-4	intact:EBI-16248|ensemblfungi:YHL004W|uniprotkb:D3DKR0	intact:EBI-11525164|ensembl:ENSP00000372391	psi-mi:rt04_yeast(display_long)|uniprotkb:MRP4(gene name)|psi-mi:MRP4(display_short)|uniprotkb:MRP4A(gene name synonym)|uniprotkb:Mitochondrial small ribosomal subunit protein uS2m(gene name synonym)|uniprotkb:YHL004W(locus name)	psi-mi:q96kn7-4(display_long)|uniprotkb:RPGRIP1(gene name)|psi-mi:RPGRIP1(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11556250|imex:IM-24995-4495	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YHL004W(gene)|ensemblfungi:YHL004W_mRNA(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR001865(Ribosomal protein S2)|interpro:IPR005706(Ribosomal protein S2, bacterial-type)|interpro:IPR018130|interpro:IPR023591|rcsb pdb:5MRC|rcsb pdb:5MRE|rcsb pdb:5MRF|refseq:NP_011859.1|sgd:S000000996|dip:DIP-5035N|mint:P32902|sgd:YHL004W(identity)	intact:EBI-1050213(isoform-parent)|ensembl:ENSG00000092200(gene)|ensembl:ENST00000382933(transcript)|uniprotkb:Q96KN7-4(isoform-parent)|entrezgene/locuslink:57096(identity)	-	crc64:81A1CB33134BC559	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:BlL3W6HUN+uAKF/AxwlV1zT5YZQ559292	rogid:Xy0433uM/nWhWLM/EsfESPJDIy49606	intact-crc:80F785DA59B298ED|rigid:XlxHB0UGXHGaHmIOBTNAOgoMUEc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96HT8	uniprotkb:P32902	intact:EBI-748896|uniprotkb:Q6NXT8|uniprotkb:Q9P0J5|uniprotkb:B2R6R0|ensembl:ENSP00000318154	intact:EBI-16248|ensemblfungi:YHL004W|uniprotkb:D3DKR0	psi-mi:mr1l1_human(display_long)|uniprotkb:PP784(orf name)|uniprotkb:MRFAP1L1(gene name)|psi-mi:MRFAP1L1(display_short)	psi-mi:rt04_yeast(display_long)|uniprotkb:MRP4(gene name)|psi-mi:MRP4(display_short)|uniprotkb:MRP4A(gene name synonym)|uniprotkb:Mitochondrial small ribosomal subunit protein uS2m(gene name synonym)|uniprotkb:YHL004W(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11556241|imex:IM-24995-4494	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_982287.1|refseq:XP_005247989.1|ensembl:ENSG00000178988(gene)|ensembl:ENST00000320848(transcript)|go:"GO:0042802"(identical protein binding)|interpro:IPR029254|mint:Q96HT8|dip:DIP-29019N|entrezgene/locuslink:114932(identity)	ensemblfungi:YHL004W(gene)|ensemblfungi:YHL004W_mRNA(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR001865(Ribosomal protein S2)|interpro:IPR005706(Ribosomal protein S2, bacterial-type)|interpro:IPR018130|interpro:IPR023591|rcsb pdb:5MRC|rcsb pdb:5MRE|rcsb pdb:5MRF|refseq:NP_011859.1|sgd:S000000996|dip:DIP-5035N|mint:P32902|sgd:YHL004W(identity)	-	caution:This sequence has been withdrawn from Uniprot.|crc64:6C914B0B4BEECAE5	crc64:81A1CB33134BC559	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:hb4enqSS7DeieOByDoLDkXkSlIk9606	rogid:BlL3W6HUN+uAKF/AxwlV1zT5YZQ559292	intact-crc:741A84C8F8138711|rigid:BDBlsC/ZZCeS2HYGVz/rgdVL+1Y	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96ED9-2	uniprotkb:P32902	intact:EBI-10961706|ensembl:ENSP00000264827	intact:EBI-16248|ensemblfungi:YHL004W|uniprotkb:D3DKR0	psi-mi:q96ed9-2(display_long)|uniprotkb:HOOK2(gene name)|psi-mi:HOOK2(display_short)	psi-mi:rt04_yeast(display_long)|uniprotkb:MRP4(gene name)|psi-mi:MRP4(display_short)|uniprotkb:MRP4A(gene name synonym)|uniprotkb:Mitochondrial small ribosomal subunit protein uS2m(gene name synonym)|uniprotkb:YHL004W(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11556232|imex:IM-24995-4493	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000095066(gene)|ensembl:ENST00000264827(transcript)|intact:EBI-743290(isoform-parent)|uniprotkb:Q96ED9-2(isoform-parent)|entrezgene/locuslink:29911(identity)	ensemblfungi:YHL004W(gene)|ensemblfungi:YHL004W_mRNA(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR001865(Ribosomal protein S2)|interpro:IPR005706(Ribosomal protein S2, bacterial-type)|interpro:IPR018130|interpro:IPR023591|rcsb pdb:5MRC|rcsb pdb:5MRE|rcsb pdb:5MRF|refseq:NP_011859.1|sgd:S000000996|dip:DIP-5035N|mint:P32902|sgd:YHL004W(identity)	-	-	crc64:81A1CB33134BC559	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:aJZ/iDJpRk5dFL1NiouLuTjnOnc9606	rogid:BlL3W6HUN+uAKF/AxwlV1zT5YZQ559292	intact-crc:2C3C7CC621904B29|rigid:mdXrbh47M7UccastJZrUUg9uqFo	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q93062-3	uniprotkb:P32902	intact:EBI-740343|ensembl:ENSP00000340176	intact:EBI-16248|ensemblfungi:YHL004W|uniprotkb:D3DKR0	psi-mi:q93062-3(display_long)|uniprotkb:RBPMS(gene name)|psi-mi:RBPMS(display_short)|uniprotkb:HERMES(gene name synonym)|uniprotkb:Heart and RRM expressed sequence(gene name synonym)	psi-mi:rt04_yeast(display_long)|uniprotkb:MRP4(gene name)|psi-mi:MRP4(display_short)|uniprotkb:MRP4A(gene name synonym)|uniprotkb:Mitochondrial small ribosomal subunit protein uS2m(gene name synonym)|uniprotkb:YHL004W(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11556223|imex:IM-24995-4492	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-740322(rbpms_human)|uniprotkb:Q93062-3(isoform-parent)|ensembl:ENSG00000157110(gene)|ensembl:ENST00000339877(transcript)|entrezgene/locuslink:11030(identity)	ensemblfungi:YHL004W(gene)|ensemblfungi:YHL004W_mRNA(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR001865(Ribosomal protein S2)|interpro:IPR005706(Ribosomal protein S2, bacterial-type)|interpro:IPR018130|interpro:IPR023591|rcsb pdb:5MRC|rcsb pdb:5MRE|rcsb pdb:5MRF|refseq:NP_011859.1|sgd:S000000996|dip:DIP-5035N|mint:P32902|sgd:YHL004W(identity)	-	-	crc64:81A1CB33134BC559	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:nlPMQAJoKEbPYBwsL3xodmCKd7c9606	rogid:BlL3W6HUN+uAKF/AxwlV1zT5YZQ559292	intact-crc:7D41A2B3C43F6D56|rigid:mOQLEyFM/aDCReQLyjzL2d09iKY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8WXE1-3	uniprotkb:P32902	intact:EBI-11524582|ensembl:ENSP00000400930	intact:EBI-16248|ensemblfungi:YHL004W|uniprotkb:D3DKR0	psi-mi:q8wxe1-3(display_long)|uniprotkb:ATRIP(gene name)|psi-mi:ATRIP(display_short)|uniprotkb:AGS1(gene name synonym)|uniprotkb:ATM and Rad3-related-interacting protein(gene name synonym)	psi-mi:rt04_yeast(display_long)|uniprotkb:MRP4(gene name)|psi-mi:MRP4(display_short)|uniprotkb:MRP4A(gene name synonym)|uniprotkb:Mitochondrial small ribosomal subunit protein uS2m(gene name synonym)|uniprotkb:YHL004W(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11556214|imex:IM-24995-4491	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-747353(isoform-parent)|ensembl:ENSG00000164053(gene)|ensembl:ENST00000412052(transcript)|entrezgene/locuslink:84126(identity)	ensemblfungi:YHL004W(gene)|ensemblfungi:YHL004W_mRNA(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR001865(Ribosomal protein S2)|interpro:IPR005706(Ribosomal protein S2, bacterial-type)|interpro:IPR018130|interpro:IPR023591|rcsb pdb:5MRC|rcsb pdb:5MRE|rcsb pdb:5MRF|refseq:NP_011859.1|sgd:S000000996|dip:DIP-5035N|mint:P32902|sgd:YHL004W(identity)	-	isoform-comment:No experimental confirmation available.	crc64:81A1CB33134BC559	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:NKCjy1jGZEySEhUOf8rJ6h9pyxY9606	rogid:BlL3W6HUN+uAKF/AxwlV1zT5YZQ559292	intact-crc:389A8D47EB6A27EF|rigid:q4kObxihjWSQ6C9C1opduIO+Xp0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8WWB3	uniprotkb:P32902	intact:EBI-740680|ensembl:ENSP00000361276|ensembl:ENSP00000361278|ensembl:ENSP00000402890|uniprotkb:Q5QP03|uniprotkb:Q5QP04|uniprotkb:Q6WNP4|uniprotkb:Q6ZU87|uniprotkb:A8K927	intact:EBI-16248|ensemblfungi:YHL004W|uniprotkb:D3DKR0	psi-mi:dydc1_human(display_long)|uniprotkb:DYDC1(gene name)|psi-mi:DYDC1(display_short)|uniprotkb:DPY30D1(gene name synonym)|uniprotkb:RSD9(orf name)|uniprotkb:RSD-9(orf name)	psi-mi:rt04_yeast(display_long)|uniprotkb:MRP4(gene name)|psi-mi:MRP4(display_short)|uniprotkb:MRP4A(gene name synonym)|uniprotkb:Mitochondrial small ribosomal subunit protein uS2m(gene name synonym)|uniprotkb:YHL004W(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11556205|imex:IM-24995-4490	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_620167.1|ensembl:ENSG00000170788(gene)|ensembl:ENST00000372202(transcript)|ensembl:ENST00000372204(transcript)|ensembl:ENST00000421924(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0006348"|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|interpro:IPR007858(Dpy-30)|interpro:IPR037856|refseq:XP_011537636.1|refseq:XP_011537637.1|refseq:NP_001255982.1|refseq:XP_005269606.1|refseq:XP_005269607.1|entrezgene/locuslink:143241(identity)	ensemblfungi:YHL004W(gene)|ensemblfungi:YHL004W_mRNA(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR001865(Ribosomal protein S2)|interpro:IPR005706(Ribosomal protein S2, bacterial-type)|interpro:IPR018130|interpro:IPR023591|rcsb pdb:5MRC|rcsb pdb:5MRE|rcsb pdb:5MRF|refseq:NP_011859.1|sgd:S000000996|dip:DIP-5035N|mint:P32902|sgd:YHL004W(identity)	-	-	crc64:81A1CB33134BC559	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:W6GUazYFXZGHGijUBpAJ5GiRuXA9606	rogid:BlL3W6HUN+uAKF/AxwlV1zT5YZQ559292	intact-crc:0FFC9A192483C222|rigid:WzjHYqsDg3w44cS5krinjUt9vpI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32902	uniprotkb:Q8NHQ1	intact:EBI-16248|ensemblfungi:YHL004W|uniprotkb:D3DKR0	intact:EBI-739624|ensembl:ENSP00000264982|ensembl:ENSP00000419231|uniprotkb:Q96B31|uniprotkb:Q9H2C3|uniprotkb:Q9H2Z1|uniprotkb:Q9H940|uniprotkb:D3DNE9|uniprotkb:B7Z5I8|uniprotkb:B7Z7E8|uniprotkb:F5GZX8	psi-mi:rt04_yeast(display_long)|uniprotkb:MRP4(gene name)|psi-mi:MRP4(display_short)|uniprotkb:MRP4A(gene name synonym)|uniprotkb:Mitochondrial small ribosomal subunit protein uS2m(gene name synonym)|uniprotkb:YHL004W(locus name)	psi-mi:cep70_human(display_long)|uniprotkb:CEP70(gene name)|psi-mi:CEP70(display_short)|uniprotkb:BITE(gene name synonym)|uniprotkb:p10-binding protein(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11556196|imex:IM-24995-4489	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YHL004W(gene)|ensemblfungi:YHL004W_mRNA(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR001865(Ribosomal protein S2)|interpro:IPR005706(Ribosomal protein S2, bacterial-type)|interpro:IPR018130|interpro:IPR023591|rcsb pdb:5MRC|rcsb pdb:5MRE|rcsb pdb:5MRF|refseq:NP_011859.1|sgd:S000000996|dip:DIP-5035N|mint:P32902|sgd:YHL004W(identity)	ensembl:ENSG00000114107(gene)|ensembl:ENST00000264982(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|interpro:IPR019734|interpro:IPR037692|mint:Q8NHQ1|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|ensembl:ENST00000484888(transcript)|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_077817.2|refseq:XP_016862764.1|refseq:NP_001275893.1|refseq:NP_001275894.1|refseq:NP_001275895.1|refseq:NP_001275896.1|refseq:NP_001307527.1|refseq:NP_001307529.1|entrezgene/locuslink:80321(identity)	-	crc64:81A1CB33134BC559	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:BlL3W6HUN+uAKF/AxwlV1zT5YZQ559292	rogid:S4yveQWcvdVtAUX65gqrJ5Dv0Mc9606	intact-crc:258A64B647711D65|rigid:J2sM+DbG+y7tjVL8ykgESazQzJQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32902	uniprotkb:Q8NA61-2	intact:EBI-16248|ensemblfungi:YHL004W|uniprotkb:D3DKR0	intact:EBI-11524851|ensembl:ENSP00000368249|ensembl:ENSP00000480148	psi-mi:rt04_yeast(display_long)|uniprotkb:MRP4(gene name)|psi-mi:MRP4(display_short)|uniprotkb:MRP4A(gene name synonym)|uniprotkb:Mitochondrial small ribosomal subunit protein uS2m(gene name synonym)|uniprotkb:YHL004W(locus name)	psi-mi:q8na61-2(display_long)|uniprotkb:CBY2(gene name)|psi-mi:CBY2(display_short)|uniprotkb:SPERT(gene name synonym)|uniprotkb:Spermatid-associated protein(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11556187|imex:IM-24995-4488	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YHL004W(gene)|ensemblfungi:YHL004W_mRNA(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR001865(Ribosomal protein S2)|interpro:IPR005706(Ribosomal protein S2, bacterial-type)|interpro:IPR018130|interpro:IPR023591|rcsb pdb:5MRC|rcsb pdb:5MRE|rcsb pdb:5MRF|refseq:NP_011859.1|sgd:S000000996|dip:DIP-5035N|mint:P32902|sgd:YHL004W(identity)	intact:EBI-741724(isoform-parent)|ensembl:ENSG00000174015(gene)|ensembl:ENST00000378966(transcript)|ensembl:ENST00000610924(transcript)|uniprotkb:Q8NA61-2(isoform-parent)|entrezgene/locuslink:220082(identity)	-	crc64:81A1CB33134BC559	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:BlL3W6HUN+uAKF/AxwlV1zT5YZQ559292	rogid:SogYcXGGMYRYzB9xKC5o0pEtsDs9606	intact-crc:2E1E814482311A73|rigid:efXubap58mIr57EWgtd3RkV3SoM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8N6Y0	uniprotkb:P32902	intact:EBI-739895|uniprotkb:Q8NBX7|uniprotkb:Q96KH3|uniprotkb:Q9BYI8|uniprotkb:A8K7L6|uniprotkb:B2RCR9|ensembl:ENSP00000252597	intact:EBI-16248|ensemblfungi:YHL004W|uniprotkb:D3DKR0	psi-mi:usbp1_human(display_long)|uniprotkb:USHBP1(gene name)|psi-mi:USHBP1(display_short)|uniprotkb:MCC-2(gene name synonym)|uniprotkb:AIE-75-binding protein(gene name synonym)|uniprotkb:AIEBP(gene name synonym)|uniprotkb:MCC2(gene name synonym)|uniprotkb:Mutated in colon cancer protein 2(gene name synonym)	psi-mi:rt04_yeast(display_long)|uniprotkb:MRP4(gene name)|psi-mi:MRP4(display_short)|uniprotkb:MRP4A(gene name synonym)|uniprotkb:Mitochondrial small ribosomal subunit protein uS2m(gene name synonym)|uniprotkb:YHL004W(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11556178|imex:IM-24995-4487	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001284632.1|refseq:NP_114147.2|refseq:NP_001308346.1|ensembl:ENSG00000130307(gene)|ensembl:ENST00000252597(transcript)|go:"GO:0030165"(PDZ domain binding)|interpro:IPR019536|interpro:IPR040171|entrezgene/locuslink:83878(identity)	ensemblfungi:YHL004W(gene)|ensemblfungi:YHL004W_mRNA(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR001865(Ribosomal protein S2)|interpro:IPR005706(Ribosomal protein S2, bacterial-type)|interpro:IPR018130|interpro:IPR023591|rcsb pdb:5MRC|rcsb pdb:5MRE|rcsb pdb:5MRF|refseq:NP_011859.1|sgd:S000000996|dip:DIP-5035N|mint:P32902|sgd:YHL004W(identity)	-	-	crc64:81A1CB33134BC559	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:vY1qx73Ju/z7WDu6k1kd10ZDVRo9606	rogid:BlL3W6HUN+uAKF/AxwlV1zT5YZQ559292	intact-crc:B23D624E3375C8C8|rigid:UpZ7rQV1DYkju5zEWzt11XSJgZ0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P33297	uniprotkb:P62333	intact:EBI-13920|uniprotkb:D6W2H6|ensemblfungi:YOR117W	intact:EBI-357669|uniprotkb:Q92524|uniprotkb:P49719|uniprotkb:Q6IBU3|uniprotkb:B2R975|ensembl:ENSP00000401802	psi-mi:prs6a_yeast(display_long)|uniprotkb:RPT5(gene name)|psi-mi:RPT5(display_short)|uniprotkb:YTA1(gene name synonym)|uniprotkb:YOR117W(locus name)|uniprotkb:O3258(orf name)|uniprotkb:YOR3258W(orf name)|uniprotkb:Tat-binding protein homolog 1(gene name synonym)	psi-mi:prs10_human(display_long)|uniprotkb:PSMC6(gene name)|psi-mi:PSMC6(display_short)|uniprotkb:SUG2(gene name synonym)|uniprotkb:Proteasome 26S subunit ATPase 6(gene name synonym)|uniprotkb:Proteasome subunit p42(gene name synonym)|uniprotkb:26S proteasome AAA-ATPase subunit RPT4(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11556296|imex:IM-24995-4500	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005643|rcsb pdb:3WHL|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MP9|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|rcsb pdb:3WHK|reactome:R-SCE-5689880|reactome:R-SCE-6798695|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|ensemblfungi:YOR117W(gene)|ensemblfungi:YOR117W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0070682"(proteasome regulatory particle assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035254|interpro:IPR041569|rcsb pdb:3JCO|rcsb pdb:3JCP|refseq:NP_014760.3|mint:P33297|dip:DIP-1590N|sgd:YOR117W(identity)	refseq:NP_002797.3|ensembl:ENST00000445930(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|ensembl:ENSG00000100519(gene)|go:"GO:0005829"(cytosol)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0016234"(inclusion body)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0042802"(identical protein binding)|interpro:IPR032501|interpro:IPR035263|interpro:IPR041569|mint:P62333|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHJ|rcsb pdb:5VHM|rcsb pdb:5VHN|rcsb pdb:5VHO|rcsb pdb:5VHP|rcsb pdb:5VHQ|rcsb pdb:5VHR|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090261"(positive regulation of inclusion body assembly)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-75815|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-174184|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|dip:DIP-38150N|entrezgene/locuslink:5706(identity)	-	crc64:C215422033FCE830	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:jsQE3SjBA0ZZcysuLgFe/5M6pOc559292	rogid:QE8jzSEp1bpzhOi/oAAnV18QK249606	intact-crc:71A8FDFF4E9E6731|rigid:tsQRSTFYX7nwVpP+XsHPhk23dng	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P33297	uniprotkb:P18848	intact:EBI-13920|uniprotkb:D6W2H6|ensemblfungi:YOR117W	intact:EBI-492498|uniprotkb:Q9UH31|ensembl:ENSP00000336790|ensembl:ENSP00000379912|ensembl:ENSP00000501783|ensembl:ENSP00000501863|ensembl:ENSP00000502400|ensembl:ENSP00000502610|ensembl:ENSP00000505360|ensembl:ENSP00000384587|intact:EBI-740263|uniprotkb:Q96AQ3	psi-mi:prs6a_yeast(display_long)|uniprotkb:RPT5(gene name)|psi-mi:RPT5(display_short)|uniprotkb:YTA1(gene name synonym)|uniprotkb:YOR117W(locus name)|uniprotkb:O3258(orf name)|uniprotkb:YOR3258W(orf name)|uniprotkb:Tat-binding protein homolog 1(gene name synonym)	psi-mi:atf4_human(display_long)|uniprotkb:Activating transcription factor 4(gene name synonym)|uniprotkb:CREB2(gene name synonym)|uniprotkb:ATF4(gene name)|psi-mi:ATF4(display_short)|uniprotkb:TXREB(gene name synonym)|uniprotkb:Cyclic AMP-responsive element-binding protein 2(gene name synonym)|uniprotkb:Tax-responsive enhancer element-binding protein 67(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11556286|imex:IM-24995-4499	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005643|rcsb pdb:3WHL|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MP9|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|rcsb pdb:3WHK|reactome:R-SCE-5689880|reactome:R-SCE-6798695|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|ensemblfungi:YOR117W(gene)|ensemblfungi:YOR117W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0070682"(proteasome regulatory particle assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035254|interpro:IPR041569|rcsb pdb:3JCO|rcsb pdb:3JCP|refseq:NP_014760.3|mint:P33297|dip:DIP-1590N|sgd:YOR117W(identity)	refseq:NP_001666.2|refseq:NP_877962.1|ensembl:ENSG00000128272(gene)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005886"(plasma membrane)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008140"(cAMP response element binding protein binding)|go:"GO:0010575"(positive regulation of vascular endothelial growth factor production)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030282"(bone mineralization)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0032057"(negative regulation of translational initiation in response to stress)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070309"(lens fiber cell morphogenesis)|go:"GO:0070982"(L-asparagine metabolic process)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0140467"(integrated stress response signaling)|go:"GO:0140468"(HRI-mediated signaling)|go:"GO:1903204"(negative regulation of oxidative stress-induced neuron death)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:1990037"(Lewy body core)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990589"(ATF4-CREB1 transcription factor complex)|go:"GO:1990590"(ATF1-ATF4 transcription factor complex)|go:"GO:1990617"(CHOP-ATF4 complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029811|mint:P18848|rcsb pdb:1CI6|reactome:R-HSA-380994|reactome:R-HSA-381042|reactome:R-HSA-381183|reactome:R-HSA-9633012|reactome:R-HSA-9648895|go:"GO:0043005"(neuron projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045667"(regulation of osteoblast differentiation)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0036003"(positive regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0036091"(positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress)|go:"GO:0036499"(PERK-mediated unfolded protein response)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0061395"(positive regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|ensembl:ENST00000337304(transcript)|ensembl:ENST00000396680(transcript)|ensembl:ENST00000404241(transcript)|ensembl:ENST00000674568(transcript)|ensembl:ENST00000674835(transcript)|ensembl:ENST00000674920(transcript)|ensembl:ENST00000676346(transcript)|ensembl:ENST00000679776(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|refseq:XP_016884296.1|dip:DIP-354N|entrezgene/locuslink:468(identity)	-	crc64:C215422033FCE830	crc64:3BBB7379DC3B0D07|comment:"No Uniprot Update and Caution  removed \" The protein could not be merged with EBI-12907955 because of some conflicts with the protein sequence (features which cannot be shifted).\" -EBI-12907955 no longer exists."	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:jsQE3SjBA0ZZcysuLgFe/5M6pOc559292	rogid:2UolKWXxKFddysaOo70/U/1pI5k9606	intact-crc:165100BE2E93D97C|rigid:LpstdSOApZI5A94yRRNDD3wsmz0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32902	uniprotkb:Q9UPY8	intact:EBI-16248|ensemblfungi:YHL004W|uniprotkb:D3DKR0	intact:EBI-726739|uniprotkb:O00265|uniprotkb:Q6FI15|uniprotkb:Q9BZP7|uniprotkb:Q9BZP8|uniprotkb:B7WPK5|uniprotkb:Q6FHB0|ensembl:ENSP00000233121	psi-mi:rt04_yeast(display_long)|uniprotkb:MRP4(gene name)|psi-mi:MRP4(display_short)|uniprotkb:MRP4A(gene name synonym)|uniprotkb:Mitochondrial small ribosomal subunit protein uS2m(gene name synonym)|uniprotkb:YHL004W(locus name)	psi-mi:mare3_human(display_long)|uniprotkb:End-binding protein 3(gene name synonym)|uniprotkb:EB1 protein family member 3(gene name synonym)|uniprotkb:RP3(gene name synonym)|uniprotkb:MAPRE3(gene name)|psi-mi:MAPRE3(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11556277|imex:IM-24995-4498	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YHL004W(gene)|ensemblfungi:YHL004W_mRNA(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR001865(Ribosomal protein S2)|interpro:IPR005706(Ribosomal protein S2, bacterial-type)|interpro:IPR018130|interpro:IPR023591|rcsb pdb:5MRC|rcsb pdb:5MRE|rcsb pdb:5MRF|refseq:NP_011859.1|sgd:S000000996|dip:DIP-5035N|mint:P32902|sgd:YHL004W(identity)	refseq:NP_036458.2|refseq:XP_016859086.1|refseq:NP_001289979.1|refseq:XP_006712030.1|refseq:XP_011531002.1|dip:DIP-56069N|ensembl:ENSG00000084764(gene)|ensembl:ENST00000233121(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0008017"(microtubule binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030496"(midbody)|go:"GO:0031110"(regulation of microtubule polymerization or depolymerization)|go:"GO:0031113"(regulation of microtubule polymerization)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0042802"(identical protein binding)|go:"GO:0045737"(positive regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051233"(spindle midzone)|go:"GO:0051301"(cell division)|go:"GO:1903033"(positive regulation of microtubule plus-end binding)|go:"GO:1904825"(protein localization to microtubule plus-end)|go:"GO:1905721"(mitotic spindle astral microtubule end)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR004953(EB1, C-terminal)|interpro:IPR027328|interpro:IPR027738|interpro:IPR036133|interpro:IPR036872|mint:Q9UPY8|rcsb pdb:1WYO|rcsb pdb:3CO1|rcsb pdb:3JAK|rcsb pdb:3JAL|rcsb pdb:3JAR|rcsb pdb:3TQ7|entrezgene/locuslink:22924(identity)	-	crc64:81A1CB33134BC559	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:BlL3W6HUN+uAKF/AxwlV1zT5YZQ559292	rogid:LHuufxyNrygS3iFW5mmg13R43NE9606	intact-crc:A225CE0028B3E808|rigid:y7KhdkY3BxPcBy0QUN8WFq2gJzU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9H892-2	uniprotkb:P32902	intact:EBI-10274410|ensembl:ENSP00000315160|ensembl:ENSP00000435291	intact:EBI-16248|ensemblfungi:YHL004W|uniprotkb:D3DKR0	psi-mi:q9h892-2(display_long)|uniprotkb:TTC12(gene name)|psi-mi:TTC12(display_short)	psi-mi:rt04_yeast(display_long)|uniprotkb:MRP4(gene name)|psi-mi:MRP4(display_short)|uniprotkb:MRP4A(gene name synonym)|uniprotkb:Mitochondrial small ribosomal subunit protein uS2m(gene name synonym)|uniprotkb:YHL004W(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11556268|imex:IM-24995-4497	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000149292(gene)|ensembl:ENST00000314756(transcript)|ensembl:ENST00000494714(transcript)|intact:EBI-2548354(isoform-parent)|uniprotkb:Q9H892-2(isoform-parent)|entrezgene/locuslink:54970(identity)	ensemblfungi:YHL004W(gene)|ensemblfungi:YHL004W_mRNA(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR001865(Ribosomal protein S2)|interpro:IPR005706(Ribosomal protein S2, bacterial-type)|interpro:IPR018130|interpro:IPR023591|rcsb pdb:5MRC|rcsb pdb:5MRE|rcsb pdb:5MRF|refseq:NP_011859.1|sgd:S000000996|dip:DIP-5035N|mint:P32902|sgd:YHL004W(identity)	-	isoform-comment:May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay.	crc64:81A1CB33134BC559	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:OEjSVGC92wY/pn1l/B1t3wDa3s89606	rogid:BlL3W6HUN+uAKF/AxwlV1zT5YZQ559292	intact-crc:9CB1E02953B6935A|rigid:zk8lMiY4sUBQ9FH8bwjlD/O+26U	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9BV19	uniprotkb:P32902	intact:EBI-2874661|ensembl:ENSP00000361603	intact:EBI-16248|ensemblfungi:YHL004W|uniprotkb:D3DKR0	psi-mi:ca050_human(display_long)|uniprotkb:C1orf50(gene name)|psi-mi:C1orf50(display_short)	psi-mi:rt04_yeast(display_long)|uniprotkb:MRP4(gene name)|psi-mi:MRP4(display_short)|uniprotkb:MRP4A(gene name synonym)|uniprotkb:Mitochondrial small ribosomal subunit protein uS2m(gene name synonym)|uniprotkb:YHL004W(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11556259|imex:IM-24995-4496	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000164008(gene)|ensembl:ENST00000372525(transcript)|go:"GO:0042802"(identical protein binding)|interpro:IPR019534|refseq:NP_077002.2|entrezgene/locuslink:79078(identity)	ensemblfungi:YHL004W(gene)|ensemblfungi:YHL004W_mRNA(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR001865(Ribosomal protein S2)|interpro:IPR005706(Ribosomal protein S2, bacterial-type)|interpro:IPR018130|interpro:IPR023591|rcsb pdb:5MRC|rcsb pdb:5MRE|rcsb pdb:5MRF|refseq:NP_011859.1|sgd:S000000996|dip:DIP-5035N|mint:P32902|sgd:YHL004W(identity)	-	-	crc64:81A1CB33134BC559	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:TZfvza3lr44CQW5Piu+83qv5Igo9606	rogid:BlL3W6HUN+uAKF/AxwlV1zT5YZQ559292	intact-crc:A1869C60A9E8E366|rigid:TPzZxZtze0xixf9tIGcLTCyl0wE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9H190	uniprotkb:P33322	intact:EBI-742426|ensembl:ENSP00000371233|uniprotkb:O95892|uniprotkb:Q5W0X1|uniprotkb:Q9BZ42|uniprotkb:Q9H567|uniprotkb:Q9NRY8|intact:EBI-28983470|ensembl:ENSP00000342935|ensembl:ENSP00000354013	intact:EBI-4105|ensemblfungi:YLR175W|uniprotkb:D6VYH9	psi-mi:sdcb2_human(display_long)|uniprotkb:Similar to TACIP18(gene name synonym)|uniprotkb:SDCBP2(gene name)|psi-mi:SDCBP2(display_short)|uniprotkb:SITAC18(gene name synonym)|uniprotkb:Syndecan-binding protein 2(gene name synonym)	psi-mi:cbf5_yeast(display_long)|uniprotkb:Small nucleolar RNP protein CBF5(gene name synonym)|uniprotkb:L9470.11(orf name)|uniprotkb:YLR175W(locus name)|uniprotkb:CBF5(gene name)|psi-mi:CBF5(display_short)|uniprotkb:Centromere/microtubule-binding protein CBF5(gene name synonym)|uniprotkb:Centromere-binding factor 5(gene name synonym)|uniprotkb:H/ACA snoRNP protein CBF5(gene name synonym)|uniprotkb:p64'(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11556334|imex:IM-24995-4504	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001186713.1|refseq:NP_056500.2|refseq:NP_536737.3|ensembl:ENSP00000342935|ensembl:ENSP00000354013|ensembl:ENST00000381808|ensembl:ENSP00000371229|ensembl:ENSP00000371233|ensembl:ENSG00000125775(gene)|ensembl:ENST00000360779(transcript)|ensembl:ENST00000381812(transcript)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007399"(nervous system development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016607"(nuclear speck)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046907"(intracellular transport)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036034|interpro:IPR041489|ensembl:ENST00000339987(transcript)|entrezgene/locuslink:27111(identity)	ensemblfungi:YLR175W(gene)|ensemblfungi:YLR175W_mRNA(transcript)|go:"GO:0000154"(rRNA modification)|go:"GO:0000495"(box H/ACA RNA 3'-end processing)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0006364"(rRNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0009982"(pseudouridine synthase activity)|go:"GO:0030686"(90S preribosome)|go:"GO:0031118"(rRNA pseudouridine synthesis)|go:"GO:0031120"(snRNA pseudouridine synthesis)|go:"GO:0031429"(box H/ACA snoRNP complex)|go:"GO:0051301"(cell division)|go:"GO:1990481"(mRNA pseudouridine synthesis)|refseq:NP_013276.1|sgd:S000004165|dip:DIP-4472N|mint:P33322|interpro:IPR002478(PUA)|interpro:IPR002501(tRNA pseudouridine synthase B, N-terminal)|interpro:IPR004521(Uncharacterized domain 2)|interpro:IPR004802(Putative rRNA pseudouridine synthase)|interpro:IPR012960(DKCLD)|interpro:IPR015947(PUA-like)|interpro:IPR020103|interpro:IPR032819|interpro:IPR036974|rcsb pdb:3U28|rcsb pdb:3UAI|rcsb pdb:3ZV0|reactome:R-SCE-171319|sgd:YLR175W(identity)	-	-	crc64:D356B39FDCC32E2D	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:vlEtVZkwLTte5PJ4i8ce+SwE/4Y9606	rogid:cBheN/I3bpmiXhl3cWX8OT/YWco559292	intact-crc:F90BD2ABA18E051F|rigid:4zkyrwd7cHP1mj/wDfoxx/iBTEU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P33299	uniprotkb:Q16401	intact:EBI-13910|uniprotkb:D6VX51|ensemblfungi:YKL145W	intact:EBI-752143|uniprotkb:Q15045|uniprotkb:Q4VXG8|intact:EBI-10968906|uniprotkb:B4DZM8|ensembl:ENSP00000210313	psi-mi:prs7_yeast(display_long)|uniprotkb:YKL145W(locus name)|uniprotkb:RPT1(gene name)|psi-mi:RPT1(display_short)|uniprotkb:CIM5(gene name synonym)|uniprotkb:YTA3(gene name synonym)|uniprotkb:Protein CIM5(gene name synonym)|uniprotkb:Tat-binding homolog 3(gene name synonym)	psi-mi:psmd5_human(display_long)|uniprotkb:26S proteasome subunit S5B(gene name synonym)|uniprotkb:26S protease subunit S5 basic(gene name synonym)|uniprotkb:PSMD5(gene name)|psi-mi:PSMD5(display_short)|uniprotkb:KIAA0072(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11556325|imex:IM-24995-4503	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012777.1|sgd:S000001628|ensemblfungi:YKL145W(gene)|go:"GO:0070682"(proteasome regulatory particle assembly)|interpro:IPR003593(AAA+ ATPase, core)|ensemblfungi:YKL145W_mRNA(transcript)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|go:"GO:0005524"(ATP binding)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR035245|interpro:IPR041569|rcsb pdb:3JCO|rcsb pdb:3JCP|go:"GO:0005634"(nucleus)|rcsb pdb:3VLF|rcsb pdb:4A3V|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:4JPO|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|rcsb pdb:5A5B|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|rcsb pdb:5MP9|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0045732"(positive regulation of protein catabolic process)|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-6798695|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|rcsb pdb:6EF3|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|mint:P33299|dip:DIP-2883N|sgd:YKL145W(identity)	refseq:NP_005038.1|refseq:NP_001257356.1|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|ensembl:ENSG00000095261(gene)|ensembl:ENST00000210313(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0070682"(proteasome regulatory particle assembly)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR019538|mint:Q16401|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|entrezgene/locuslink:5711(identity)	-	crc64:8454BBC9D549EC5C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:8XXo53yZ1KevHObtYWABeFr0hWo559292	rogid:XLVvCeWct98fvc6ktvaWNXwt9dE9606	intact-crc:CA645D1B874A91B4|rigid:I7TUR8lYODCxwSY3l1utKDnZ0a8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P33297	uniprotkb:Q9Y2J4	intact:EBI-13920|uniprotkb:D6W2H6|ensemblfungi:YOR117W	intact:EBI-746752|intact:EBI-28986657|ensembl:ENSP00000409999|uniprotkb:Q53EP1|uniprotkb:Q96F99|uniprotkb:Q9UKB4|uniprotkb:A8K6F1|uniprotkb:B7Z5Q1|uniprotkb:E9PHW3	psi-mi:prs6a_yeast(display_long)|uniprotkb:RPT5(gene name)|psi-mi:RPT5(display_short)|uniprotkb:YTA1(gene name synonym)|uniprotkb:YOR117W(locus name)|uniprotkb:O3258(orf name)|uniprotkb:YOR3258W(orf name)|uniprotkb:Tat-binding protein homolog 1(gene name synonym)	psi-mi:amol2_human(display_long)|uniprotkb:Leman coiled-coil protein(gene name synonym)|uniprotkb:AMOTL2(gene name)|psi-mi:AMOTL2(display_short)|uniprotkb:KIAA0989(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11556314|imex:IM-24995-4502	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005643|rcsb pdb:3WHL|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MP9|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|rcsb pdb:3WHK|reactome:R-SCE-5689880|reactome:R-SCE-6798695|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|ensemblfungi:YOR117W(gene)|ensemblfungi:YOR117W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0070682"(proteasome regulatory particle assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035254|interpro:IPR041569|rcsb pdb:3JCO|rcsb pdb:3JCP|refseq:NP_014760.3|mint:P33297|dip:DIP-1590N|sgd:YOR117W(identity)	refseq:NP_001265612.1|refseq:NP_001265614.1|ensembl:ENSG00000114019(gene)|refseq:XP_006713717.1|refseq:NP_057285.3|refseq:XP_011511183.1|ensembl:ENST00000422605(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0003365"(establishment of cell polarity involved in ameboidal cell migration)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0035329"(hippo signaling)|go:"GO:0055037"(recycling endosome)|interpro:IPR009114(Angiomotin)|interpro:IPR024646|mint:Q9Y2J4|reactome:R-HSA-2028269|refseq:XP_016862069.1|refseq:XP_016862070.1|refseq:XP_016862071.1|ensembl:ENST00000249883|ensembl:ENSP00000249883|ensembl:ENSP00000409999|ensembl:ENST00000513145|ensembl:ENSP00000425475|ensembl:ENST00000514516|ensembl:ENSP00000424765|dip:DIP-57510N|entrezgene/locuslink:51421(identity)	-	crc64:C215422033FCE830	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:jsQE3SjBA0ZZcysuLgFe/5M6pOc559292	rogid:SHtKAcLLnTpSSLwVE7yQ1WECoZk9606	intact-crc:FAFC6B83C93C6E53|rigid:trg69QZNG/6NNJMYouXfyimxBg0	false	-	sufficient binding region:314-779	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9P2K3-2	uniprotkb:P33297	intact:EBI-1504830|ensembl:ENSP00000355973	intact:EBI-13920|uniprotkb:D6W2H6|ensemblfungi:YOR117W	psi-mi:q9p2k3-2(display_long)|uniprotkb:RCOR3(gene name)|psi-mi:RCOR3(display_short)|uniprotkb:KIAA1343(gene name synonym)	psi-mi:prs6a_yeast(display_long)|uniprotkb:RPT5(gene name)|psi-mi:RPT5(display_short)|uniprotkb:YTA1(gene name synonym)|uniprotkb:YOR117W(locus name)|uniprotkb:O3258(orf name)|uniprotkb:YOR3258W(orf name)|uniprotkb:Tat-binding protein homolog 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11556305|imex:IM-24995-4501	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000117625(gene)|ensembl:ENST00000367006(transcript)|intact:EBI-743428(isoform-parent)|uniprotkb:Q9P2K3-2(isoform-parent)|entrezgene/locuslink:55758(identity)	sgd:S000005643|rcsb pdb:3WHL|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MP9|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|rcsb pdb:3WHK|reactome:R-SCE-5689880|reactome:R-SCE-6798695|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|ensemblfungi:YOR117W(gene)|ensemblfungi:YOR117W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0070682"(proteasome regulatory particle assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035254|interpro:IPR041569|rcsb pdb:3JCO|rcsb pdb:3JCP|refseq:NP_014760.3|mint:P33297|dip:DIP-1590N|sgd:YOR117W(identity)	-	isoform-comment:No experimental confirmation available.	crc64:C215422033FCE830	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:RU9KkQB+JnxYVfG5IlAeNKnVFjw9606	rogid:jsQE3SjBA0ZZcysuLgFe/5M6pOc559292	intact-crc:1AAD054ABF4B71C0|rigid:KGMSSmrer4j3RPiU5j612Dn4HRc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P33417	uniprotkb:P63279	intact:EBI-9401|ensemblfungi:YKL032C|uniprotkb:D6VXQ4	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	psi-mi:ixr1_yeast(display_long)|uniprotkb:IXR1(gene name)|psi-mi:IXR1(display_short)|uniprotkb:ORD1(gene name synonym)|uniprotkb:YKL032C(locus name)|uniprotkb:YKL245(orf name)|uniprotkb:Structure-specific recognition protein(gene name synonym)	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11556352|imex:IM-24995-4506	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YKL032C(gene)|ensemblfungi:YKL032C_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0072718"(response to cisplatin)|go:"GO:0090069"(regulation of ribosome biogenesis)|go:"GO:2000819"(regulation of nucleotide-excision repair)|go:"GO:0005634"(nucleus)|reactome:R-SCE-5620971|reactome:R-SCE-5686938|reactome:R-SCE-6798695|sgd:S000001515|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR036910|refseq:NP_012893.3|interpro:IPR033311|reactome:R-SCE-140342|sgd:YKL032C(identity)	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N|entrezgene/locuslink:7329(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:owYbshNfmIe1+4PkRItBvAQ2GN0559292	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	intact-crc:BD651A2BE084AD93|rigid:1+ptW9qqRSPyAxtnJ7cZhUVrGeQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P33417	uniprotkb:B0QYN7	intact:EBI-9401|ensemblfungi:YKL032C|uniprotkb:D6VXQ4	intact:EBI-11525376|ensembl:ENSP00000384361	psi-mi:ixr1_yeast(display_long)|uniprotkb:IXR1(gene name)|psi-mi:IXR1(display_short)|uniprotkb:ORD1(gene name synonym)|uniprotkb:YKL032C(locus name)|uniprotkb:YKL245(orf name)|uniprotkb:Structure-specific recognition protein(gene name synonym)	psi-mi:b0qyn7_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11556343|imex:IM-24995-4505	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YKL032C(gene)|ensemblfungi:YKL032C_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0072718"(response to cisplatin)|go:"GO:0090069"(regulation of ribosome biogenesis)|go:"GO:2000819"(regulation of nucleotide-excision repair)|go:"GO:0005634"(nucleus)|reactome:R-SCE-5620971|reactome:R-SCE-5686938|reactome:R-SCE-6798695|sgd:S000001515|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR036910|refseq:NP_012893.3|interpro:IPR033311|reactome:R-SCE-140342|sgd:YKL032C(identity)	refseq:XP_005255597.1|refseq:XP_005255598.1|refseq:XP_011520946.1|refseq:XP_011520947.1|ensembl:ENSG00000103275(gene)|ensembl:ENST00000402301(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0016740"(transferase activity)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|entrezgene/locuslink:7329(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:owYbshNfmIe1+4PkRItBvAQ2GN0559292	rogid:zMqQOA+nnCUquTIxAUwemkElTYI9606	intact-crc:D463603572B69EE8|rigid:5YXDqeqEV5DFKDVx4WmvJ0fP0ik	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P34164	uniprotkb:Q9BQ66	intact:EBI-17187|uniprotkb:D6VTU7|ensemblfungi:YGL208W	intact:EBI-739863|uniprotkb:A3KMC5|uniprotkb:Q495I0|ensembl:ENSP00000377582|ensembl:ENSP00000458979	psi-mi:sip2_yeast(display_long)|uniprotkb:SIP2(gene name)|psi-mi:SIP2(display_short)|uniprotkb:SPM2(gene name synonym)|uniprotkb:YGL208W(locus name)|uniprotkb:G1155(orf name)|uniprotkb:Protein SPM2(gene name synonym)|uniprotkb:SNF1-interacting protein 2(gene name synonym)	psi-mi:kr412_human(display_long)|uniprotkb:KRTAP4-12(gene name)|psi-mi:KRTAP4-12(display_short)|uniprotkb:KAP4.12(gene name synonym)|uniprotkb:KRTAP4.12(gene name synonym)|uniprotkb:Keratin-associated protein 4.12(gene name synonym)|uniprotkb:Ultrahigh sulfur keratin-associated protein 4.12(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11556397|imex:IM-24995-4511	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011307.1|sgd:S000003176|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0080090"(regulation of primary metabolic process)|go:"GO:2000222"(positive regulation of pseudohyphal growth)|interpro:IPR006828(5-AMP-activated protein kinase, beta subunit, complex-interacting region)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030077|interpro:IPR032640|interpro:IPR037256|rcsb pdb:2QLV|rcsb pdb:3T4N|rcsb pdb:3TDH|rcsb pdb:3TE5|reactome:R-SCE-1632852|reactome:R-SCE-380972|go:"GO:0043254"(regulation of protein-containing complex assembly)|ensemblfungi:YGL208W(gene)|ensemblfungi:YGL208W_mRNA(transcript)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0042149"(cellular response to glucose starvation)|dip:DIP-865N|mint:P34164|sgd:YGL208W(identity)	refseq:NP_114060.1|ensembl:ENSG00000213416(gene)|ensembl:ENSG00000263236(gene)|ensembl:ENST00000394014(transcript)|ensembl:ENST00000571271(transcript)|go:"GO:0045095"(keratin filament)|interpro:IPR002494(Keratin, high sulphur B2 protein)|entrezgene/locuslink:83755(identity)	-	crc64:CBB4FCE0070A563F	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:KBJuNhrNAHm6B0INUd1UIiASmok559292	rogid:XLiYOwNd549kn287BJWgx5zmDCY9606	intact-crc:9F18557492EEF8CC|rigid:hJwboUKLqAXxX4FMOLJNHYPWlWM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P34164	uniprotkb:Q99750	intact:EBI-17187|uniprotkb:D6VTU7|ensemblfungi:YGL208W	intact:EBI-724076|ensembl:ENSP00000230321|ensembl:ENSP00000362142	psi-mi:sip2_yeast(display_long)|uniprotkb:SIP2(gene name)|psi-mi:SIP2(display_short)|uniprotkb:SPM2(gene name synonym)|uniprotkb:YGL208W(locus name)|uniprotkb:G1155(orf name)|uniprotkb:Protein SPM2(gene name synonym)|uniprotkb:SNF1-interacting protein 2(gene name synonym)	psi-mi:mdfi_human(display_long)|uniprotkb:Myogenic repressor I-mf(gene name synonym)|uniprotkb:MDFI(gene name)|psi-mi:MDFI(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11556388|imex:IM-24995-4510	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011307.1|sgd:S000003176|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0080090"(regulation of primary metabolic process)|go:"GO:2000222"(positive regulation of pseudohyphal growth)|interpro:IPR006828(5-AMP-activated protein kinase, beta subunit, complex-interacting region)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030077|interpro:IPR032640|interpro:IPR037256|rcsb pdb:2QLV|rcsb pdb:3T4N|rcsb pdb:3TDH|rcsb pdb:3TE5|reactome:R-SCE-1632852|reactome:R-SCE-380972|go:"GO:0043254"(regulation of protein-containing complex assembly)|ensemblfungi:YGL208W(gene)|ensemblfungi:YGL208W_mRNA(transcript)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0042149"(cellular response to glucose starvation)|dip:DIP-865N|mint:P34164|sgd:YGL208W(identity)	refseq:NP_005577.1|ensembl:ENSG00000112559(gene)|ensembl:ENST00000230321(transcript)|ensembl:ENST00000373051(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR026134|mint:Q99750|refseq:NP_001287733.1|refseq:NP_001287734.1|refseq:NP_001287735.1|entrezgene/locuslink:4188(identity)	-	crc64:CBB4FCE0070A563F	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:KBJuNhrNAHm6B0INUd1UIiASmok559292	rogid:V3vU0fihMOW18DMHAiDbuZ3asNU9606	intact-crc:F43EECBEBA9041BC|rigid:lVjeUXAAI3amze6bCE5iNeVAqCk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q92997	uniprotkb:P33750	intact:EBI-739789|uniprotkb:O14642|uniprotkb:Q13531|uniprotkb:Q8N5E9|uniprotkb:Q92607|uniprotkb:D3DNT0|intact:EBI-11081380|uniprotkb:B4E3E5|ensembl:ENSP00000316054	intact:EBI-17651|uniprotkb:D6VXZ1|ensemblfungi:YLL011W	psi-mi:dvl3_human(display_long)|uniprotkb:DVL3(gene name)|psi-mi:DVL3(display_short)|uniprotkb:KIAA0208(gene name synonym)|uniprotkb:DSH homolog 3(gene name synonym)	psi-mi:dca13_yeast(display_long)|uniprotkb:SOF1(gene name)|psi-mi:SOF1(display_short)|uniprotkb:YLL011W(locus name)|uniprotkb:L1339(orf name)|uniprotkb:U3 small nucleolar RNA-associated protein SOF1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11556379|imex:IM-24995-4509	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004414.3|dip:DIP-34509N|ensembl:ENSG00000161202(gene)|ensembl:ENST00000313143(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002020"(protease binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005109"(frizzled binding)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0038031"(non-canonical Wnt signaling pathway via JNK cascade)|go:"GO:0042493"|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050821"(protein stabilization)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0150012"(positive regulation of neuron projection arborization)|go:"GO:1903827"|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008342(Dishevelled-3 protein, C-terminal)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:Q92997|rcsb pdb:6V7O|rcsb pdb:6ZC6|rcsb pdb:6ZC8|reactome:R-HSA-201681|reactome:R-HSA-201688|reactome:R-HSA-4086400|reactome:R-HSA-4641258|reactome:R-HSA-4641262|reactome:R-HSA-5368598|reactome:R-HSA-5663220|reactome:R-HSA-9673324|entrezgene/locuslink:1857(identity)	ensemblfungi:YLL011W(gene)|ensemblfungi:YLL011W_mRNA(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003729"(mRNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0030686"(90S preribosome)|go:"GO:0032040"(small-subunit processome)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR007287(Sof1-like protein)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR020472|interpro:IPR036322|rcsb pdb:5WLC|rcsb pdb:6KE6|rcsb pdb:6LQP|rcsb pdb:6LQQ|rcsb pdb:6LQR|rcsb pdb:6LQS|rcsb pdb:6LQT|rcsb pdb:6LQU|rcsb pdb:6LQV|rcsb pdb:6ND4|rcsb pdb:6ZQA|rcsb pdb:6ZQB|rcsb pdb:6ZQC|rcsb pdb:6ZQD|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-6791226|refseq:NP_013090.1|sgd:S000003934|dip:DIP-746N|mint:P33750|sgd:YLL011W(identity)	-	-	crc64:4B28371CC61DE7E4	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:yJ3YIp5IhvKTQwa3bK5yTjNyqXk9606	rogid:stTLdABNsa3SvTkNOZBteSNAVJA559292	intact-crc:B1817BE185E26370|rigid:MKlnYeGFXqo+k8PhzoxLEikprNI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P33750	uniprotkb:O14641	intact:EBI-17651|uniprotkb:D6VXZ1|ensemblfungi:YLL011W	intact:EBI-740850|ensembl:ENSP00000005340|uniprotkb:Q53XM0|uniprotkb:D3DTN3	psi-mi:dca13_yeast(display_long)|uniprotkb:SOF1(gene name)|psi-mi:SOF1(display_short)|uniprotkb:YLL011W(locus name)|uniprotkb:L1339(orf name)|uniprotkb:U3 small nucleolar RNA-associated protein SOF1(gene name synonym)	psi-mi:dvl2_human(display_long)|uniprotkb:DSH homolog 2(gene name synonym)|uniprotkb:DVL2(gene name)|psi-mi:DVL2(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11556370|imex:IM-24995-4508	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YLL011W(gene)|ensemblfungi:YLL011W_mRNA(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003729"(mRNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0030686"(90S preribosome)|go:"GO:0032040"(small-subunit processome)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR007287(Sof1-like protein)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR020472|interpro:IPR036322|rcsb pdb:5WLC|rcsb pdb:6KE6|rcsb pdb:6LQP|rcsb pdb:6LQQ|rcsb pdb:6LQR|rcsb pdb:6LQS|rcsb pdb:6LQT|rcsb pdb:6LQU|rcsb pdb:6LQV|rcsb pdb:6ND4|rcsb pdb:6ZQA|rcsb pdb:6ZQB|rcsb pdb:6ZQC|rcsb pdb:6ZQD|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-6791226|refseq:NP_013090.1|sgd:S000003934|dip:DIP-746N|mint:P33750|sgd:YLL011W(identity)	refseq:NP_004413.1|ensembl:ENSG00000004975(gene)|ensembl:ENST00000005340(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005109"(frizzled binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0007507"(heart development)|go:"GO:0016235"(aggresome)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044340"(canonical Wnt signaling pathway involved in regulation of cell proliferation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0150012"(positive regulation of neuron projection arborization)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008341(Dishevelled-2 region)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:O14641|rcsb pdb:2REY|rcsb pdb:3CBX|rcsb pdb:3CBY|rcsb pdb:3CBZ|rcsb pdb:3CC0|rcsb pdb:4WIP|rcsb pdb:5LNP|rcsb pdb:5SUY|rcsb pdb:5SUZ|rcsb pdb:6IW3|rcsb pdb:6JCK|reactome:R-HSA-201681|reactome:R-HSA-201688|reactome:R-HSA-2028269|reactome:R-HSA-4086400|reactome:R-HSA-4608870|reactome:R-HSA-4641258|reactome:R-HSA-4641262|reactome:R-HSA-5099900|reactome:R-HSA-5368598|reactome:R-HSA-5663220|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9673324|ensembl:ENSP00000005340|dip:DIP-34433N|entrezgene/locuslink:1856(identity)	-	crc64:4B28371CC61DE7E4	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:stTLdABNsa3SvTkNOZBteSNAVJA559292	rogid:2Vdc8oRnT4Mz/j+EXQXrL3AszOc9606	intact-crc:7B8292F88E2A76D2|rigid:j4xjxtpoVQnl/tte5rWikoJ91So	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P33441	uniprotkb:Q9BW62	intact:EBI-10841|ensemblfungi:YML062C|uniprotkb:D6VZB1	intact:EBI-743591|uniprotkb:A8K5X4|ensembl:ENSP00000369989|ensembl:ENSP00000369991	psi-mi:mft1_yeast(display_long)|uniprotkb:YML062C(locus name)|uniprotkb:MFT1(gene name)|psi-mi:MFT1(display_short)|uniprotkb:Mitochondrial fusion target protein 1(gene name synonym)	psi-mi:katl1_human(display_long)|uniprotkb:p60 katanin-like 1(gene name synonym)|uniprotkb:KATNAL1(gene name)|psi-mi:KATNAL1(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11556361|imex:IM-24995-4507	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0006397"(mRNA processing)|ensemblfungi:YML062C(gene)|ensemblfungi:YML062C_mRNA(transcript)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0034063"(stress granule assembly)|go:"GO:0060090"(molecular adaptor activity)|interpro:IPR008501(Protein of unknown function DUF783)|go:"GO:0000445"(THO complex part of transcription export complex)|go:"GO:0000446"(nucleoplasmic THO complex)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0006310"(DNA recombination)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|rcsb pdb:7APX|rcsb pdb:7AQO|rcsb pdb:7LUV|refseq:NP_013649.1|sgd:S000004527|mint:P33441|dip:DIP-4537N|sgd:YML062C(identity)	refseq:NP_001014402.1|refseq:NP_115492.1|refseq:XP_005266631.1|ensembl:ENSG00000102781(gene)|ensembl:ENST00000380615(transcript)|ensembl:ENST00000380617(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005874"(microtubule)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008017"(microtubule binding)|go:"GO:0008568"(microtubule-severing ATPase activity)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016853"(isomerase activity)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0042802"(identical protein binding)|go:"GO:0051013"(microtubule severing)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR027417|interpro:IPR028594|interpro:IPR028596|interpro:IPR041569|rcsb pdb:6B5C|entrezgene/locuslink:84056(identity)	-	crc64:45A775F8C1DA3E29	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:QFj+JFK+eAlExAo8oPxdoeJOpNY559292	rogid:Usi4KXsvZnNfMOGuWVSz4mfrTaE9606	intact-crc:F1AEC7BD0784AD08|rigid:vg/BvNAYp1SCVbcB+iAfapVORnk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O43765	uniprotkb:P35180	intact:EBI-347996|ensembl:ENSP00000221566|ensembl:ENSP00000503397|ensembl:ENSP00000504495|uniprotkb:Q9BTZ9|intact:EBI-1045243|uniprotkb:Q6FIA9|uniprotkb:D6W610	intact:EBI-12522|uniprotkb:D6VUL4|ensemblfungi:YGR082W	psi-mi:sgta_human(display_long)|uniprotkb:SGTA(gene name)|psi-mi:SGTA(display_short)|uniprotkb:SGT(gene name synonym)|uniprotkb:Alpha-SGT(gene name synonym)|uniprotkb:Vpu-binding protein(gene name synonym)|uniprotkb:SGT1(gene name synonym)	psi-mi:tom20_yeast(display_long)|uniprotkb:MOM19(gene name synonym)|uniprotkb:YGR082W(locus name)|uniprotkb:TOM20(gene name)|psi-mi:TOM20(display_short)|uniprotkb:MAS20(gene name synonym)|uniprotkb:Mitochondrial 20 kDa outer membrane protein(gene name synonym)|uniprotkb:Translocase of outer membrane 20 kDa subunit(gene name synonym)|uniprotkb:Protein MAS20(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11556469|imex:IM-24995-4519	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:4CPG|rcsb pdb:4GOD|rcsb pdb:4GOE|rcsb pdb:4GOF|reactome:R-HSA-9609523|rcsb pdb:2VYI|ensembl:ENSG00000104969(gene)|ensembl:ENST00000221566(transcript)|ensembl:ENST00000676943(transcript)|ensembl:ENST00000677149(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072380"(TRC complex)|go:"GO:0098850"(extrinsic component of synaptic vesicle membrane)|go:"GO:1903070"(negative regulation of ER-associated ubiquitin-dependent protein catabolic process)|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)|go:"GO:1903646"(positive regulation of chaperone-mediated protein folding)|go:"GO:1904288"(BAT3 complex binding)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR032374|mint:O43765|refseq:XP_011526480.1|refseq:NP_003012.1|entrezgene/locuslink:6449(identity)	ensemblfungi:YGR082W(gene)|ensemblfungi:YGR082W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005742"(mitochondrial outer membrane translocase complex)|go:"GO:0016031"(tRNA import into mitochondrion)|go:"GO:0030150"(protein import into mitochondrial matrix)|go:"GO:0030943"(mitochondrion targeting sequence binding)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|interpro:IPR002056(Protein import receptor MAS20)|interpro:IPR023392|refseq:NP_011596.1|sgd:S000003314|dip:DIP-2539N|mint:P35180|sgd:YGR082W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:r/Cyj4UJk/cS8QdrbjhTZMPCigI9606	rogid:7U00YLVWcaegWlJEKzGblv6STx4559292	intact-crc:52843B8B73133268|rigid:tCGv0+3PfHGj2CCWFtHvrRZkpUo	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P35179	uniprotkb:Q8N6L0	intact:EBI-16406|ensemblfungi:YDR086C|uniprotkb:D6VS73	intact:EBI-749265|uniprotkb:Q96MC3|ensembl:ENSP00000404220	psi-mi:sc61g_yeast(display_long)|uniprotkb:Sec61 complex subunit SSS1(gene name synonym)|uniprotkb:Ssh1 complex subunit SSS1(gene name synonym)|uniprotkb:D4475(orf name)|uniprotkb:YDR086C(locus name)|uniprotkb:SSS1(gene name)|psi-mi:SSS1(display_short)|uniprotkb:Sec61 complex subunit gamma(gene name synonym)|uniprotkb:Ssh1 complex subunit gamma(gene name synonym)	psi-mi:kash5_human(display_long)|uniprotkb:KASH5(gene name)|psi-mi:KASH5(display_short)|uniprotkb:CCDC155(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 155(gene name synonym)|uniprotkb:KASH domain-containing protein 5(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11556460|imex:IM-24995-4518	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YDR086C(gene)|ensemblfungi:YDR086C_mRNA(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0015450"(protein-transporting ATPase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0071261"(Ssh1 translocon complex)|interpro:IPR001901(Protein secE/sec61-gamma protein)|interpro:IPR008158(Protein translocase SEC61 complex gamma subunit)|interpro:IPR023391|rcsb pdb:2WW9|rcsb pdb:2WWA|rcsb pdb:6N3Q|rcsb pdb:6ND1|rcsb pdb:7AFT|rcsb pdb:7KAH|rcsb pdb:7KAI|rcsb pdb:7KAJ|rcsb pdb:7KAO|rcsb pdb:7KAP|rcsb pdb:7KAQ|rcsb pdb:7KAR|rcsb pdb:7KAS|rcsb pdb:7KAT|rcsb pdb:7KAU|rcsb pdb:7KB5|reactome:R-SCE-9609523|refseq:NP_010371.1|sgd:S000002493|dip:DIP-2432N|mint:P35179|sgd:YDR086C(identity)	refseq:NP_653289.3|ensembl:ENSG00000161609(gene)|ensembl:ENST00000447857(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034397"(telomere localization)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051225"(spindle assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0090172"(microtubule cytoskeleton organization involved in homologous chromosome segregation)|go:"GO:0090220"(chromosome localization to nuclear envelope involved in homologous chromosome segregation)|go:"GO:0090619"(meiotic spindle pole)|interpro:IPR011992(EF-Hand type)|interpro:IPR028168|interpro:IPR028170|interpro:IPR039508|mint:Q8N6L0|rcsb pdb:6R2I|rcsb pdb:6WMF|entrezgene/locuslink:147872(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:QIi5kN/8mDxTSvxRiJVi2JsPdws559292	rogid:Wl9L7AcvDHCZuKjYLn8QgGIbZTc9606	intact-crc:BB5DBE449297E6A0|rigid:psdiHjU6yqzLy7znfHlfC8W4pSM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P35176	uniprotkb:Q9Y2W7	intact:EBI-5458|uniprotkb:D6VST3|ensemblfungi:YDR304C	intact:EBI-751501|uniprotkb:Q53TJ5|uniprotkb:Q96T40|uniprotkb:Q9UJ84|uniprotkb:Q9UJ85|uniprotkb:Q3YAC3|uniprotkb:Q3YAC4|uniprotkb:H7BY46|ensembl:ENSP00000295225	psi-mi:cypd_yeast(display_long)|uniprotkb:CPR5(gene name)|psi-mi:CPR5(display_short)|uniprotkb:YDR304C(locus name)|uniprotkb:D9740.14(orf name)|uniprotkb:CYP5(gene name synonym)|uniprotkb:CYPD(gene name synonym)|uniprotkb:Cyclophilin D(gene name synonym)|uniprotkb:Rotamase D(gene name synonym)	psi-mi:csen_human(display_long)|uniprotkb:Kv channel-interacting protein 3(gene name synonym)|uniprotkb:A-type potassium channel modulatory protein 3(gene name synonym)|uniprotkb:DRE-antagonist modulator(gene name synonym)|uniprotkb:KCNIP3(gene name)|psi-mi:KCNIP3(display_short)|uniprotkb:DREAM(gene name synonym)|uniprotkb:KCHIP3(gene name synonym)|uniprotkb:CSEN(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11556451|imex:IM-24995-4517	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002712|refseq:NP_010590.3|dip:DIP-5222N|mint:P35176|ensemblfungi:YDR304C(gene)|ensemblfungi:YDR304C_mRNA(transcript)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006457"(protein folding)|go:"GO:0016018"(cyclosporin A binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|interpro:IPR020892|interpro:IPR029000|sgd:YDR304C(identity)	refseq:NP_001030086.1|refseq:NP_038462.1|ensembl:ENSG00000115041(gene)|ensembl:ENST00000295225(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005244"(voltage-gated ion channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0030425"(dendrite)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0043679"(axon terminus)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:1901379"(regulation of potassium ion transmembrane transport)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR028846|rcsb pdb:2E6W|reactome:R-HSA-5576894|entrezgene/locuslink:30818(identity)	-	crc64:F4861424C8443B58	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:aCn3loYoSVWfy5Tb5i+MsOHcUEo559292	rogid:Mqp4XdEur4uc6jY9dGsn8CHLE4w9606	intact-crc:72B2CFFA7FB8B5A1|rigid:Rgk6L/T/O7f9603f2m87crcxBaE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UMX0	uniprotkb:P35176	intact:EBI-741480|uniprotkb:Q8IXS9|uniprotkb:Q8N2Q3|uniprotkb:Q9H0T8|uniprotkb:Q9H3R4|uniprotkb:Q9HAZ5|intact:EBI-28967608|ensembl:ENSP00000365576|uniprotkb:Q5T6J5|uniprotkb:Q5T6J9|uniprotkb:A0A024R284	intact:EBI-5458|uniprotkb:D6VST3|ensemblfungi:YDR304C	psi-mi:ubql1_human(display_long)|uniprotkb:Protein linking IAP with cytoskeleton 1(gene name synonym)|uniprotkb:UBQLN1(gene name)|psi-mi:UBQLN1(display_short)|uniprotkb:DA41(gene name synonym)|uniprotkb:PLIC1(gene name synonym)	psi-mi:cypd_yeast(display_long)|uniprotkb:CPR5(gene name)|psi-mi:CPR5(display_short)|uniprotkb:YDR304C(locus name)|uniprotkb:D9740.14(orf name)|uniprotkb:CYP5(gene name synonym)|uniprotkb:CYPD(gene name synonym)|uniprotkb:Cyclophilin D(gene name synonym)|uniprotkb:Rotamase D(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11556442|imex:IM-24995-4516	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000257468|ensembl:ENSP00000257468|ensembl:ENSP00000365576|ensembl:ENSG00000135018(gene)|ensembl:ENST00000376395(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000502"(proteasome complex)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016235"(aggresome)|go:"GO:0016236"(macroautophagy)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0019900"(kinase binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035973"(aggrephagy)|go:"GO:0042802"(identical protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0097352"(autophagosome maturation)|go:"GO:1901340"(negative regulation of store-operated calcium channel activity)|go:"GO:1902175"(regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)|interpro:IPR000626(Ubiquitin)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR028430|interpro:IPR029071|mint:Q9UMX0|rcsb pdb:2JY5|rcsb pdb:2JY6|rcsb pdb:2KLC|reactome:R-HSA-8856825|refseq:NP_038466.2|refseq:NP_444295.1|dip:DIP-41629N|entrezgene/locuslink:29979(identity)	sgd:S000002712|refseq:NP_010590.3|dip:DIP-5222N|mint:P35176|ensemblfungi:YDR304C(gene)|ensemblfungi:YDR304C_mRNA(transcript)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006457"(protein folding)|go:"GO:0016018"(cyclosporin A binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|interpro:IPR020892|interpro:IPR029000|sgd:YDR304C(identity)	-	-	crc64:F4861424C8443B58	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:nCFfZbGCTvRYaXhQ4R99XblslvM9606	rogid:aCn3loYoSVWfy5Tb5i+MsOHcUEo559292	intact-crc:A4ADC38772151F14|rigid:YcVJPAT45FfmKo8R3+pr/TEAB2w	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P35176	uniprotkb:Q96EQ0	intact:EBI-5458|uniprotkb:D6VST3|ensemblfungi:YDR304C	intact:EBI-744081|ensembl:ENSP00000370395	psi-mi:cypd_yeast(display_long)|uniprotkb:CPR5(gene name)|psi-mi:CPR5(display_short)|uniprotkb:YDR304C(locus name)|uniprotkb:D9740.14(orf name)|uniprotkb:CYP5(gene name synonym)|uniprotkb:CYPD(gene name synonym)|uniprotkb:Cyclophilin D(gene name synonym)|uniprotkb:Rotamase D(gene name synonym)	psi-mi:sgtb_human(display_long)|uniprotkb:Beta-SGT(gene name synonym)|uniprotkb:Small glutamine-rich protein with tetratricopeptide repeats 2(gene name synonym)|uniprotkb:SGTB(gene name)|psi-mi:SGTB(display_short)|uniprotkb:SGT2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11556433|imex:IM-24995-4515	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002712|refseq:NP_010590.3|dip:DIP-5222N|mint:P35176|ensemblfungi:YDR304C(gene)|ensemblfungi:YDR304C_mRNA(transcript)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006457"(protein folding)|go:"GO:0016018"(cyclosporin A binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|interpro:IPR020892|interpro:IPR029000|sgd:YDR304C(identity)	refseq:NP_061945.1|refseq:XP_005248605.1|ensembl:ENSG00000197860(gene)|ensembl:ENST00000381007(transcript)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0072380"(TRC complex)|go:"GO:1903646"(positive regulation of chaperone-mediated protein folding)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR032374|entrezgene/locuslink:54557(identity)	-	crc64:F4861424C8443B58	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:aCn3loYoSVWfy5Tb5i+MsOHcUEo559292	rogid:emIgH8U/yVmXT00Ty9yybIqQqas9606	intact-crc:E000D19A207B2573|rigid:moBP3cAFyw6oKkz6/z7bg7JEHGU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P46379-2	uniprotkb:P35176	intact:EBI-10988864|ensembl:ENSP00000211379|ensembl:ENSP00000365143|ensembl:ENSP00000372938|ensembl:ENSP00000372940|ensembl:ENSP00000389121|ensembl:ENSP00000410156|ensembl:ENSP00000412110|ensembl:ENSP00000413698	intact:EBI-5458|uniprotkb:D6VST3|ensemblfungi:YDR304C	psi-mi:p46379-2(display_long)|uniprotkb:BAG6(gene name)|psi-mi:BAG6(display_short)|uniprotkb:BAG family molecular chaperone regulator 6(gene name synonym)|uniprotkb:BAT3(gene name synonym)|uniprotkb:BCL2-associated athanogene 6(gene name synonym)|uniprotkb:G3(gene name synonym)|uniprotkb:HLA-B-associated transcript 3(gene name synonym)|uniprotkb:Protein G3(gene name synonym)|uniprotkb:Protein Scythe(gene name synonym)	psi-mi:cypd_yeast(display_long)|uniprotkb:CPR5(gene name)|psi-mi:CPR5(display_short)|uniprotkb:YDR304C(locus name)|uniprotkb:D9740.14(orf name)|uniprotkb:CYP5(gene name synonym)|uniprotkb:CYPD(gene name synonym)|uniprotkb:Cyclophilin D(gene name synonym)|uniprotkb:Rotamase D(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11556424|imex:IM-24995-4514	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-347552(isoform-parent)|uniprotkb:P46379-2(isoform-parent)|ensembl:ENSG00000096155(gene)|ensembl:ENSG00000204463(gene)|ensembl:ENSG00000229524(gene)|ensembl:ENSG00000233348(gene)|ensembl:ENST00000211379(transcript)|ensembl:ENST00000375976(transcript)|ensembl:ENST00000383446(transcript)|ensembl:ENST00000383448(transcript)|ensembl:ENST00000417144(transcript)|ensembl:ENST00000419847(transcript)|ensembl:ENST00000442479(transcript)|ensembl:ENST00000443182(transcript)|entrezgene/locuslink:7917(identity)	sgd:S000002712|refseq:NP_010590.3|dip:DIP-5222N|mint:P35176|ensemblfungi:YDR304C(gene)|ensemblfungi:YDR304C_mRNA(transcript)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006457"(protein folding)|go:"GO:0016018"(cyclosporin A binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|interpro:IPR020892|interpro:IPR029000|sgd:YDR304C(identity)	-	-	crc64:F4861424C8443B58	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:7y9hxqfcTmnCBRON6qNoHPCdODY9606	rogid:aCn3loYoSVWfy5Tb5i+MsOHcUEo559292	intact-crc:FE8EA419F5FF9078|rigid:yPAhK57/pKkWvoSCATzZn63M5Oo	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P35176	uniprotkb:O43765	intact:EBI-5458|uniprotkb:D6VST3|ensemblfungi:YDR304C	intact:EBI-347996|ensembl:ENSP00000221566|ensembl:ENSP00000503397|ensembl:ENSP00000504495|uniprotkb:Q9BTZ9|intact:EBI-1045243|uniprotkb:Q6FIA9|uniprotkb:D6W610	psi-mi:cypd_yeast(display_long)|uniprotkb:CPR5(gene name)|psi-mi:CPR5(display_short)|uniprotkb:YDR304C(locus name)|uniprotkb:D9740.14(orf name)|uniprotkb:CYP5(gene name synonym)|uniprotkb:CYPD(gene name synonym)|uniprotkb:Cyclophilin D(gene name synonym)|uniprotkb:Rotamase D(gene name synonym)	psi-mi:sgta_human(display_long)|uniprotkb:SGTA(gene name)|psi-mi:SGTA(display_short)|uniprotkb:SGT(gene name synonym)|uniprotkb:Alpha-SGT(gene name synonym)|uniprotkb:Vpu-binding protein(gene name synonym)|uniprotkb:SGT1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11556415|imex:IM-24995-4513	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002712|refseq:NP_010590.3|dip:DIP-5222N|mint:P35176|ensemblfungi:YDR304C(gene)|ensemblfungi:YDR304C_mRNA(transcript)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006457"(protein folding)|go:"GO:0016018"(cyclosporin A binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|interpro:IPR020892|interpro:IPR029000|sgd:YDR304C(identity)	rcsb pdb:4CPG|rcsb pdb:4GOD|rcsb pdb:4GOE|rcsb pdb:4GOF|reactome:R-HSA-9609523|rcsb pdb:2VYI|ensembl:ENSG00000104969(gene)|ensembl:ENST00000221566(transcript)|ensembl:ENST00000676943(transcript)|ensembl:ENST00000677149(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072380"(TRC complex)|go:"GO:0098850"(extrinsic component of synaptic vesicle membrane)|go:"GO:1903070"(negative regulation of ER-associated ubiquitin-dependent protein catabolic process)|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)|go:"GO:1903646"(positive regulation of chaperone-mediated protein folding)|go:"GO:1904288"(BAT3 complex binding)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR032374|mint:O43765|refseq:XP_011526480.1|refseq:NP_003012.1|entrezgene/locuslink:6449(identity)	-	crc64:F4861424C8443B58	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:aCn3loYoSVWfy5Tb5i+MsOHcUEo559292	rogid:r/Cyj4UJk/cS8QdrbjhTZMPCigI9606	intact-crc:31516EF2F5E1AE29|rigid:qQgJzAnQ9luCe7HRjqJy0vldZ2A	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O43681	uniprotkb:P35176	intact:EBI-2515857|ensembl:ENSP00000349887|ensembl:ENSP00000466379|uniprotkb:Q53FC6|uniprotkb:A8K740|uniprotkb:A6NHP8|uniprotkb:Q92849|intact:EBI-2818109	intact:EBI-5458|uniprotkb:D6VST3|ensemblfungi:YDR304C	psi-mi:get3_human(display_long)|uniprotkb:GET3(gene name)|psi-mi:GET3(display_short)|uniprotkb:ARSA(gene name synonym)|uniprotkb:ASNA1(gene name synonym)|uniprotkb:Arsenical pump-driving ATPase(gene name synonym)|uniprotkb:Arsenite-stimulated ATPase(gene name synonym)|uniprotkb:Guided entry of tail-anchored proteins factor 3, ATPase(gene name synonym)|uniprotkb:TRC40(gene name synonym)|uniprotkb:Transmembrane domain recognition complex 40 kDa ATPase subunit(gene name synonym)|uniprotkb:hARSA-I(gene name synonym)|uniprotkb:hASNA-I(gene name synonym)	psi-mi:cypd_yeast(display_long)|uniprotkb:CPR5(gene name)|psi-mi:CPR5(display_short)|uniprotkb:YDR304C(locus name)|uniprotkb:D9740.14(orf name)|uniprotkb:CYP5(gene name synonym)|uniprotkb:CYPD(gene name synonym)|uniprotkb:Cyclophilin D(gene name synonym)|uniprotkb:Rotamase D(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11556406|imex:IM-24995-4512	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000198356(gene)|ensembl:ENST00000357332(transcript)|ensembl:ENST00000591090(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0015105"(arsenite transmembrane transporter activity)|go:"GO:0016787"(hydrolase activity)|go:"GO:0043529"(GET complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|interpro:IPR016300(Arsenite-transporting ATPase)|interpro:IPR025723|interpro:IPR027417|interpro:IPR027542|mint:O43681|rcsb pdb:6SO5|reactome:R-HSA-9609523|refseq:NP_004308.2|entrezgene/locuslink:439(identity)	sgd:S000002712|refseq:NP_010590.3|dip:DIP-5222N|mint:P35176|ensemblfungi:YDR304C(gene)|ensemblfungi:YDR304C_mRNA(transcript)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006457"(protein folding)|go:"GO:0016018"(cyclosporin A binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|interpro:IPR020892|interpro:IPR029000|sgd:YDR304C(identity)	-	-	crc64:F4861424C8443B58	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:j2jKZb3MH8Bd3hnoQhDO6bjbyxI9606	rogid:aCn3loYoSVWfy5Tb5i+MsOHcUEo559292	intact-crc:487F151753300F21|rigid:o1R26f3SK3+5prTF5ubQbsjwHwU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q08379	uniprotkb:P35184	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	intact:EBI-17971|uniprotkb:D6VVU2|ensemblfungi:YIR012W	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:sqt1_yeast(display_long)|uniprotkb:YIB12W(orf name)|uniprotkb:YIR012W(locus name)|uniprotkb:SQT1(gene name)|psi-mi:SQT1(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11556523|imex:IM-24995-4525	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N|entrezgene/locuslink:2801(identity)	refseq:NP_012277.1|sgd:S000001451|ensemblfungi:YIR012W_mRNA(transcript)|ensemblfungi:YIR012W(gene)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|rcsb pdb:4ZOV|rcsb pdb:4ZOX|rcsb pdb:5AMS|dip:DIP-2508N|mint:P35184|sgd:YIR012W(identity)	-	-	crc64:981D566076B0C881	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2017/05/26	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	rogid:u/Q5uAjR85ZD3op0nHiN20IVCLY559292	intact-crc:168B8BBB1FE9ECDD|rigid:4cdxPE30cCZSDpIJI9J3f+4xJLw	false	sufficient binding region:383-1002	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P35182	uniprotkb:Q8WV92	intact:EBI-12784|uniprotkb:D6VRY2|ensemblfungi:YDL006W	intact:EBI-2691489|uniprotkb:Q69YV0|ensembl:ENSP00000289359	psi-mi:pp2c1_yeast(display_long)|uniprotkb:PTC1(gene name)|psi-mi:PTC1(display_short)|uniprotkb:TPD1(gene name synonym)|uniprotkb:YDL006W(locus name)|uniprotkb:D2925(orf name)	psi-mi:mitd1_human(display_long)|uniprotkb:MITD1(gene name)|psi-mi:MITD1(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11556514|imex:IM-24995-4524	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR000222(Protein phosphatase 2C,  manganese/magnesium aspartate binding site)|interpro:IPR001932(Protein phosphatase 2C-related)|interpro:IPR015655(Protein phosphatase 2C)|interpro:IPR036457|ensemblfungi:YDL006W(gene)|ensemblfungi:YDL006W_mRNA(transcript)|go:"GO:0000001"(mitochondrion inheritance)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006388"(tRNA splicing, via endonucleolytic cleavage and ligation)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0046872"(metal ion binding)|go:"GO:0051389"(obsolete inactivation of MAPKK activity)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1990439"(MAP kinase serine/threonine phosphatase activity)|refseq:NP_010278.3|sgd:S000002164|mint:P35182|dip:DIP-1537N|sgd:YDL006W(identity)	refseq:NP_620153.1|refseq:NP_001307346.1|refseq:NP_001307347.1|refseq:NP_001307348.1|ensembl:ENSG00000158411(gene)|ensembl:ENST00000289359(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030496"(midbody)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0061952"(midbody abscission)|go:"GO:0070062"(extracellular exosome)|interpro:IPR007330(MIT)|interpro:IPR032341|interpro:IPR036181|interpro:IPR038113|rcsb pdb:2YMB|rcsb pdb:4A5X|rcsb pdb:4A5Z|entrezgene/locuslink:129531(identity)	-	crc64:FA384D2541B20D50	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:iWNdaik/M9S814zgZEQNyOktcX8559292	rogid:VY5MeLAmoWXB0gKSJR3d9OhT1Vk9606	intact-crc:5E7A26E900529204|rigid:knJUSs7YD4HeXZ2EhLi6hDFYgDI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UHV2	uniprotkb:P35180	intact:EBI-748601|uniprotkb:Q9BUE7|ensembl:ENSP00000350633	intact:EBI-12522|uniprotkb:D6VUL4|ensemblfungi:YGR082W	psi-mi:srtd1_human(display_long)|uniprotkb:Transcriptional regulator interacting with the PHD-bromodomain 1(gene name synonym)|uniprotkb:CDK4-binding protein p34SEI1(gene name synonym)|uniprotkb:SERTAD1(gene name)|psi-mi:SERTAD1(display_short)|uniprotkb:SEI1(gene name synonym)|uniprotkb:TRIPBR1(gene name synonym)	psi-mi:tom20_yeast(display_long)|uniprotkb:MOM19(gene name synonym)|uniprotkb:YGR082W(locus name)|uniprotkb:TOM20(gene name)|psi-mi:TOM20(display_short)|uniprotkb:MAS20(gene name synonym)|uniprotkb:Mitochondrial 20 kDa outer membrane protein(gene name synonym)|uniprotkb:Translocase of outer membrane 20 kDa subunit(gene name synonym)|uniprotkb:Protein MAS20(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11556505|imex:IM-24995-4523	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_037508.2|ensembl:ENSG00000197019(gene)|ensembl:ENST00000357949(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048096"|interpro:IPR009263(SERTA)|mint:Q9UHV2|entrezgene/locuslink:29950(identity)	ensemblfungi:YGR082W(gene)|ensemblfungi:YGR082W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005742"(mitochondrial outer membrane translocase complex)|go:"GO:0016031"(tRNA import into mitochondrion)|go:"GO:0030150"(protein import into mitochondrial matrix)|go:"GO:0030943"(mitochondrion targeting sequence binding)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|interpro:IPR002056(Protein import receptor MAS20)|interpro:IPR023392|refseq:NP_011596.1|sgd:S000003314|dip:DIP-2539N|mint:P35180|sgd:YGR082W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:40dvjniwxY/UQiyoVREicctpWe09606	rogid:7U00YLVWcaegWlJEKzGblv6STx4559292	intact-crc:95E36DB555C2C5CE|rigid:gFB1jmG7TnN9Eb/EoV3Dfz5AHN0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8NHQ1	uniprotkb:P35180	intact:EBI-739624|ensembl:ENSP00000264982|ensembl:ENSP00000419231|uniprotkb:Q96B31|uniprotkb:Q9H2C3|uniprotkb:Q9H2Z1|uniprotkb:Q9H940|uniprotkb:D3DNE9|uniprotkb:B7Z5I8|uniprotkb:B7Z7E8|uniprotkb:F5GZX8	intact:EBI-12522|uniprotkb:D6VUL4|ensemblfungi:YGR082W	psi-mi:cep70_human(display_long)|uniprotkb:CEP70(gene name)|psi-mi:CEP70(display_short)|uniprotkb:BITE(gene name synonym)|uniprotkb:p10-binding protein(gene name synonym)	psi-mi:tom20_yeast(display_long)|uniprotkb:MOM19(gene name synonym)|uniprotkb:YGR082W(locus name)|uniprotkb:TOM20(gene name)|psi-mi:TOM20(display_short)|uniprotkb:MAS20(gene name synonym)|uniprotkb:Mitochondrial 20 kDa outer membrane protein(gene name synonym)|uniprotkb:Translocase of outer membrane 20 kDa subunit(gene name synonym)|uniprotkb:Protein MAS20(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11556496|imex:IM-24995-4522	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114107(gene)|ensembl:ENST00000264982(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|interpro:IPR019734|interpro:IPR037692|mint:Q8NHQ1|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|ensembl:ENST00000484888(transcript)|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_077817.2|refseq:XP_016862764.1|refseq:NP_001275893.1|refseq:NP_001275894.1|refseq:NP_001275895.1|refseq:NP_001275896.1|refseq:NP_001307527.1|refseq:NP_001307529.1|entrezgene/locuslink:80321(identity)	ensemblfungi:YGR082W(gene)|ensemblfungi:YGR082W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005742"(mitochondrial outer membrane translocase complex)|go:"GO:0016031"(tRNA import into mitochondrion)|go:"GO:0030150"(protein import into mitochondrial matrix)|go:"GO:0030943"(mitochondrion targeting sequence binding)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|interpro:IPR002056(Protein import receptor MAS20)|interpro:IPR023392|refseq:NP_011596.1|sgd:S000003314|dip:DIP-2539N|mint:P35180|sgd:YGR082W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:S4yveQWcvdVtAUX65gqrJ5Dv0Mc9606	rogid:7U00YLVWcaegWlJEKzGblv6STx4559292	intact-crc:E0CE6C2FE4521BB0|rigid:z7WBjT6L0UwP5vPIEbn0OubQKjM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8N6Y0	uniprotkb:P35180	intact:EBI-739895|uniprotkb:Q8NBX7|uniprotkb:Q96KH3|uniprotkb:Q9BYI8|uniprotkb:A8K7L6|uniprotkb:B2RCR9|ensembl:ENSP00000252597	intact:EBI-12522|uniprotkb:D6VUL4|ensemblfungi:YGR082W	psi-mi:usbp1_human(display_long)|uniprotkb:USHBP1(gene name)|psi-mi:USHBP1(display_short)|uniprotkb:MCC-2(gene name synonym)|uniprotkb:AIE-75-binding protein(gene name synonym)|uniprotkb:AIEBP(gene name synonym)|uniprotkb:MCC2(gene name synonym)|uniprotkb:Mutated in colon cancer protein 2(gene name synonym)	psi-mi:tom20_yeast(display_long)|uniprotkb:MOM19(gene name synonym)|uniprotkb:YGR082W(locus name)|uniprotkb:TOM20(gene name)|psi-mi:TOM20(display_short)|uniprotkb:MAS20(gene name synonym)|uniprotkb:Mitochondrial 20 kDa outer membrane protein(gene name synonym)|uniprotkb:Translocase of outer membrane 20 kDa subunit(gene name synonym)|uniprotkb:Protein MAS20(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11556487|imex:IM-24995-4521	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001284632.1|refseq:NP_114147.2|refseq:NP_001308346.1|ensembl:ENSG00000130307(gene)|ensembl:ENST00000252597(transcript)|go:"GO:0030165"(PDZ domain binding)|interpro:IPR019536|interpro:IPR040171|entrezgene/locuslink:83878(identity)	ensemblfungi:YGR082W(gene)|ensemblfungi:YGR082W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005742"(mitochondrial outer membrane translocase complex)|go:"GO:0016031"(tRNA import into mitochondrion)|go:"GO:0030150"(protein import into mitochondrial matrix)|go:"GO:0030943"(mitochondrion targeting sequence binding)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|interpro:IPR002056(Protein import receptor MAS20)|interpro:IPR023392|refseq:NP_011596.1|sgd:S000003314|dip:DIP-2539N|mint:P35180|sgd:YGR082W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:vY1qx73Ju/z7WDu6k1kd10ZDVRo9606	rogid:7U00YLVWcaegWlJEKzGblv6STx4559292	intact-crc:43289FF0FEAFBC58|rigid:vYGsXdseBt/8LAaKlng/wBgT/jY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P35180	uniprotkb:Q53EZ4	intact:EBI-12522|uniprotkb:D6VUL4|ensemblfungi:YGR082W	intact:EBI-747776|uniprotkb:Q32WF5|uniprotkb:Q3MV20|uniprotkb:Q5VY28|uniprotkb:Q6N034|ensembl:ENSP00000360540|uniprotkb:Q96H32|uniprotkb:Q9NVS7|uniprotkb:B2RDG8|intact:EBI-10173536|uniprotkb:D3DR37|intact:EBI-28973801	psi-mi:tom20_yeast(display_long)|uniprotkb:MOM19(gene name synonym)|uniprotkb:YGR082W(locus name)|uniprotkb:TOM20(gene name)|psi-mi:TOM20(display_short)|uniprotkb:MAS20(gene name synonym)|uniprotkb:Mitochondrial 20 kDa outer membrane protein(gene name synonym)|uniprotkb:Translocase of outer membrane 20 kDa subunit(gene name synonym)|uniprotkb:Protein MAS20(gene name synonym)	psi-mi:cep55_human(display_long)|uniprotkb:Up-regulated in colon cancer 6(gene name synonym)|uniprotkb:CEP55(gene name)|psi-mi:CEP55(display_short)|uniprotkb:URCC6(gene name synonym)|uniprotkb:C10orf3(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11556478|imex:IM-24995-4520	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YGR082W(gene)|ensemblfungi:YGR082W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005742"(mitochondrial outer membrane translocase complex)|go:"GO:0016031"(tRNA import into mitochondrion)|go:"GO:0030150"(protein import into mitochondrial matrix)|go:"GO:0030943"(mitochondrion targeting sequence binding)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|interpro:IPR002056(Protein import receptor MAS20)|interpro:IPR023392|refseq:NP_011596.1|sgd:S000003314|dip:DIP-2539N|mint:P35180|sgd:YGR082W(identity)	refseq:NP_001120654.1|refseq:NP_060601.3|ensembl:ENSG00000138180(gene)|ensembl:ENST00000371485(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0014066"(regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0030496"(midbody)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042802"(identical protein binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0061952"(midbody abscission)|go:"GO:0090543"(Flemming body)|go:"GO:1904888"(cranial skeletal system development)|interpro:IPR022008|interpro:IPR038926|mint:Q53EZ4|rcsb pdb:3E1R|rcsb pdb:3WUT|rcsb pdb:3WUU|rcsb pdb:3WUV|go:"GO:0005814"(centriole)|ensembl:ENSP00000360540|dip:DIP-44581N|entrezgene/locuslink:55165(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:7U00YLVWcaegWlJEKzGblv6STx4559292	rogid:tuo36vVb8ZgPDR81YjZFNEg559w9606	intact-crc:3EA4AA262B103D86|rigid:d0peQzDL8PgCsaXwaCi695W2e0Y	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8IXK0-5	uniprotkb:P35184	intact:EBI-11527347|ensembl:ENSP00000507877	intact:EBI-17971|uniprotkb:D6VVU2|ensemblfungi:YIR012W	psi-mi:q8ixk0-5(display_long)|uniprotkb:EDR2(gene name synonym)|uniprotkb:Early development regulatory protein 2(gene name synonym)|uniprotkb:PH2(gene name synonym)|uniprotkb:PHC2(gene name)|psi-mi:PHC2(display_short)	psi-mi:sqt1_yeast(display_long)|uniprotkb:YIB12W(orf name)|uniprotkb:YIR012W(locus name)|uniprotkb:SQT1(gene name)|psi-mi:SQT1(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11556561|imex:IM-24995-4529	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000134686(gene)|ensembl:ENST00000683057(transcript)|intact:EBI-713786(isoform-parent)|uniprotkb:Q8IXK0-5(isoform-parent)|entrezgene/locuslink:1912(identity)	refseq:NP_012277.1|sgd:S000001451|ensemblfungi:YIR012W_mRNA(transcript)|ensemblfungi:YIR012W(gene)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|rcsb pdb:4ZOV|rcsb pdb:4ZOX|rcsb pdb:5AMS|dip:DIP-2508N|mint:P35184|sgd:YIR012W(identity)	-	isoform-comment:No experimental confirmation available.	crc64:981D566076B0C881	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:bkZ10pedX8mCMrcppjyd4tl7hm09606	rogid:u/Q5uAjR85ZD3op0nHiN20IVCLY559292	intact-crc:48661E45C499A3EF|rigid:Wn06aGS6Uorm+NPpnOaPqfFHt+U	false	sufficient binding region:537-859	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P35184	uniprotkb:Q53EZ4	intact:EBI-17971|uniprotkb:D6VVU2|ensemblfungi:YIR012W	intact:EBI-747776|uniprotkb:Q32WF5|uniprotkb:Q3MV20|uniprotkb:Q5VY28|uniprotkb:Q6N034|ensembl:ENSP00000360540|uniprotkb:Q96H32|uniprotkb:Q9NVS7|uniprotkb:B2RDG8|intact:EBI-10173536|uniprotkb:D3DR37|intact:EBI-28973801	psi-mi:sqt1_yeast(display_long)|uniprotkb:YIB12W(orf name)|uniprotkb:YIR012W(locus name)|uniprotkb:SQT1(gene name)|psi-mi:SQT1(display_short)	psi-mi:cep55_human(display_long)|uniprotkb:Up-regulated in colon cancer 6(gene name synonym)|uniprotkb:CEP55(gene name)|psi-mi:CEP55(display_short)|uniprotkb:URCC6(gene name synonym)|uniprotkb:C10orf3(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11556552|imex:IM-24995-4528	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012277.1|sgd:S000001451|ensemblfungi:YIR012W_mRNA(transcript)|ensemblfungi:YIR012W(gene)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|rcsb pdb:4ZOV|rcsb pdb:4ZOX|rcsb pdb:5AMS|dip:DIP-2508N|mint:P35184|sgd:YIR012W(identity)	refseq:NP_001120654.1|refseq:NP_060601.3|ensembl:ENSG00000138180(gene)|ensembl:ENST00000371485(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0014066"(regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0030496"(midbody)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042802"(identical protein binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0061952"(midbody abscission)|go:"GO:0090543"(Flemming body)|go:"GO:1904888"(cranial skeletal system development)|interpro:IPR022008|interpro:IPR038926|mint:Q53EZ4|rcsb pdb:3E1R|rcsb pdb:3WUT|rcsb pdb:3WUU|rcsb pdb:3WUV|go:"GO:0005814"(centriole)|ensembl:ENSP00000360540|dip:DIP-44581N|entrezgene/locuslink:55165(identity)	-	crc64:981D566076B0C881	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:u/Q5uAjR85ZD3op0nHiN20IVCLY559292	rogid:tuo36vVb8ZgPDR81YjZFNEg559w9606	intact-crc:3FFC616CDEBEB164|rigid:kLNE7nwqG2v/iClYBogzIR2poAo	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P35184	uniprotkb:Q12800	intact:EBI-17971|uniprotkb:D6VVU2|ensemblfungi:YIR012W	intact:EBI-717422|uniprotkb:Q12801|uniprotkb:Q9UD77|uniprotkb:A8K5E9|uniprotkb:Q9UD75|ensembl:ENSP00000257915	psi-mi:sqt1_yeast(display_long)|uniprotkb:YIB12W(orf name)|uniprotkb:YIR012W(locus name)|uniprotkb:SQT1(gene name)|psi-mi:SQT1(display_short)	psi-mi:tfcp2_human(display_long)|uniprotkb:Transcription factor LSF(gene name synonym)|uniprotkb:SAA3 enhancer factor(gene name synonym)|uniprotkb:TFCP2(gene name)|psi-mi:TFCP2(display_short)|uniprotkb:LSF(gene name synonym)|uniprotkb:SEF(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11556543|imex:IM-24995-4527	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012277.1|sgd:S000001451|ensemblfungi:YIR012W_mRNA(transcript)|ensemblfungi:YIR012W(gene)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|rcsb pdb:4ZOV|rcsb pdb:4ZOX|rcsb pdb:5AMS|dip:DIP-2508N|mint:P35184|sgd:YIR012W(identity)	refseq:NP_001166923.1|refseq:NP_001166924.1|refseq:NP_005644.2|ensembl:ENSG00000135457(gene)|ensembl:ENST00000257915(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR007604(CP2 transcription factor)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR037599|interpro:IPR041418|mint:Q12800|entrezgene/locuslink:7024(identity)	-	crc64:981D566076B0C881	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:u/Q5uAjR85ZD3op0nHiN20IVCLY559292	rogid:M7mQ08NDYxuawmUEKRgjSdIr+Og9606	intact-crc:25144E90AE02E478|rigid:FMPTmQoz52SdPqULmpj3dGDYuNo	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P14373	uniprotkb:P35184	intact:EBI-719493|uniprotkb:A2BE15|uniprotkb:Q5RJA8|uniprotkb:Q5ST26|uniprotkb:Q6LA73|uniprotkb:Q6NXR9|uniprotkb:Q9BZY6|uniprotkb:Q9UJL3|ensembl:ENSP00000383555|ensembl:ENSP00000392787|ensembl:ENSP00000405229|ensembl:ENSP00000414793|ensembl:ENSP00000366404	intact:EBI-17971|uniprotkb:D6VVU2|ensemblfungi:YIR012W	psi-mi:tri27_human(display_long)|uniprotkb:TRIM27(gene name)|psi-mi:TRIM27(display_short)|uniprotkb:RNF76(gene name synonym)|uniprotkb:RFP(gene name synonym)|uniprotkb:Ret finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 27(gene name synonym)|uniprotkb:RING finger protein 76(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM27(gene name synonym)	psi-mi:sqt1_yeast(display_long)|uniprotkb:YIB12W(orf name)|uniprotkb:YIR012W(locus name)|uniprotkb:SQT1(gene name)|psi-mi:SQT1(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11556534|imex:IM-24995-4526	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006501.1|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0090281"(negative regulation of calcium ion import)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR020457|interpro:IPR035791|interpro:IPR043136|mint:P14373|reactome:R-HSA-3232142|reactome:R-HSA-9635465|reactome:R-HSA-8948751|ensembl:ENSG00000204713(gene)|ensembl:ENSG00000215641(gene)|ensembl:ENSG00000229006(gene)|ensembl:ENSG00000234495(gene)|ensembl:ENSG00000237071(gene)|ensembl:ENST00000377199(transcript)|ensembl:ENST00000400720(transcript)|ensembl:ENST00000431123(transcript)|ensembl:ENST00000435528(transcript)|ensembl:ENST00000437160(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001650"(fibrillar center)|go:"GO:0002820"(negative regulation of adaptive immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|entrezgene/locuslink:5987(identity)	refseq:NP_012277.1|sgd:S000001451|ensemblfungi:YIR012W_mRNA(transcript)|ensemblfungi:YIR012W(gene)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|rcsb pdb:4ZOV|rcsb pdb:4ZOX|rcsb pdb:5AMS|dip:DIP-2508N|mint:P35184|sgd:YIR012W(identity)	-	-	crc64:981D566076B0C881	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:dsfH5OUghD8KSaTz1SFw9OYVTK49606	rogid:u/Q5uAjR85ZD3op0nHiN20IVCLY559292	intact-crc:06D1DAF4127A7D9B|rigid:yNAYNi8fy6ovb44xWu73iHfwTu8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9NVV9	uniprotkb:P35184	intact:EBI-741515|uniprotkb:Q53FQ1|uniprotkb:Q6IA99|ensembl:ENSP00000254250|uniprotkb:A6NCB6|uniprotkb:D3DSY5|uniprotkb:H9KV49	intact:EBI-17971|uniprotkb:D6VVU2|ensemblfungi:YIR012W	psi-mi:thap1_human(display_long)|uniprotkb:THAP1(gene name)|psi-mi:THAP1(display_short)	psi-mi:sqt1_yeast(display_long)|uniprotkb:YIB12W(orf name)|uniprotkb:YIR012W(locus name)|uniprotkb:SQT1(gene name)|psi-mi:SQT1(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11556610|imex:IM-24995-4534	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060575.1|ensembl:ENSG00000131931(gene)|ensembl:ENST00000254250(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001650"(fibrillar center)|go:"GO:0001935"(endothelial cell proliferation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007049"(cell cycle)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016605"(PML body)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR006612(Zinc finger, C2CH-type)|interpro:IPR026516|interpro:IPR038441|mint:Q9NVV9|rcsb pdb:2JTG|rcsb pdb:2KO0|rcsb pdb:2L1G|refseq:NP_945354.1|entrezgene/locuslink:55145(identity)	refseq:NP_012277.1|sgd:S000001451|ensemblfungi:YIR012W_mRNA(transcript)|ensemblfungi:YIR012W(gene)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|rcsb pdb:4ZOV|rcsb pdb:4ZOX|rcsb pdb:5AMS|dip:DIP-2508N|mint:P35184|sgd:YIR012W(identity)	-	-	crc64:981D566076B0C881	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:/KO90pu5tBnIVq9SMx1JYPXFCEQ9606	rogid:u/Q5uAjR85ZD3op0nHiN20IVCLY559292	intact-crc:7DA27BE4BE42EFBC|rigid:MYQZw2Ov9iO6TKFJqd/zpvZgQTc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P35184	uniprotkb:Q99750	intact:EBI-17971|uniprotkb:D6VVU2|ensemblfungi:YIR012W	intact:EBI-724076|ensembl:ENSP00000230321|ensembl:ENSP00000362142	psi-mi:sqt1_yeast(display_long)|uniprotkb:YIB12W(orf name)|uniprotkb:YIR012W(locus name)|uniprotkb:SQT1(gene name)|psi-mi:SQT1(display_short)	psi-mi:mdfi_human(display_long)|uniprotkb:Myogenic repressor I-mf(gene name synonym)|uniprotkb:MDFI(gene name)|psi-mi:MDFI(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11556601|imex:IM-24995-4533	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012277.1|sgd:S000001451|ensemblfungi:YIR012W_mRNA(transcript)|ensemblfungi:YIR012W(gene)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|rcsb pdb:4ZOV|rcsb pdb:4ZOX|rcsb pdb:5AMS|dip:DIP-2508N|mint:P35184|sgd:YIR012W(identity)	refseq:NP_005577.1|ensembl:ENSG00000112559(gene)|ensembl:ENST00000230321(transcript)|ensembl:ENST00000373051(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR026134|mint:Q99750|refseq:NP_001287733.1|refseq:NP_001287734.1|refseq:NP_001287735.1|entrezgene/locuslink:4188(identity)	-	crc64:981D566076B0C881	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:u/Q5uAjR85ZD3op0nHiN20IVCLY559292	rogid:V3vU0fihMOW18DMHAiDbuZ3asNU9606	intact-crc:FBCEB96DFD7C1EAA|rigid:m98TxjikmR5tLdYm+xJ8H80jw/s	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q93062-3	uniprotkb:P35184	intact:EBI-740343|ensembl:ENSP00000340176	intact:EBI-17971|uniprotkb:D6VVU2|ensemblfungi:YIR012W	psi-mi:q93062-3(display_long)|uniprotkb:RBPMS(gene name)|psi-mi:RBPMS(display_short)|uniprotkb:HERMES(gene name synonym)|uniprotkb:Heart and RRM expressed sequence(gene name synonym)	psi-mi:sqt1_yeast(display_long)|uniprotkb:YIB12W(orf name)|uniprotkb:YIR012W(locus name)|uniprotkb:SQT1(gene name)|psi-mi:SQT1(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11556592|imex:IM-24995-4532	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-740322(rbpms_human)|uniprotkb:Q93062-3(isoform-parent)|ensembl:ENSG00000157110(gene)|ensembl:ENST00000339877(transcript)|entrezgene/locuslink:11030(identity)	refseq:NP_012277.1|sgd:S000001451|ensemblfungi:YIR012W_mRNA(transcript)|ensemblfungi:YIR012W(gene)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|rcsb pdb:4ZOV|rcsb pdb:4ZOX|rcsb pdb:5AMS|dip:DIP-2508N|mint:P35184|sgd:YIR012W(identity)	-	-	crc64:981D566076B0C881	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:nlPMQAJoKEbPYBwsL3xodmCKd7c9606	rogid:u/Q5uAjR85ZD3op0nHiN20IVCLY559292	intact-crc:1A745142FA69B583|rigid:RFJo/2SQSQpoKxOsKkKuJxcY/ow	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8N9N5-2	uniprotkb:P35184	intact:EBI-11524452|ensembl:ENSP00000347125	intact:EBI-17971|uniprotkb:D6VVU2|ensemblfungi:YIR012W	psi-mi:q8n9n5-2(display_long)|uniprotkb:BANP(gene name)|psi-mi:BANP(display_short)|uniprotkb:BEN domain-containing protein 1(gene name synonym)|uniprotkb:BEND1(gene name synonym)|uniprotkb:Btg3-associated nuclear protein(gene name synonym)|uniprotkb:SMAR1(gene name synonym)|uniprotkb:Scaffold/matrix-associated region-1-binding protein(gene name synonym)	psi-mi:sqt1_yeast(display_long)|uniprotkb:YIB12W(orf name)|uniprotkb:YIR012W(locus name)|uniprotkb:SQT1(gene name)|psi-mi:SQT1(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11556583|imex:IM-24995-4531	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000172530(gene)|ensembl:ENST00000355022(transcript)|intact:EBI-744695(isoform-parent)|uniprotkb:Q8N9N5-2(isoform-parent)|entrezgene/locuslink:54971(identity)	refseq:NP_012277.1|sgd:S000001451|ensemblfungi:YIR012W_mRNA(transcript)|ensemblfungi:YIR012W(gene)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|rcsb pdb:4ZOV|rcsb pdb:4ZOX|rcsb pdb:5AMS|dip:DIP-2508N|mint:P35184|sgd:YIR012W(identity)	-	-	crc64:981D566076B0C881	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:ESe6iCAhvq+i57fQHz3rGyg6UOo9606	rogid:u/Q5uAjR85ZD3op0nHiN20IVCLY559292	intact-crc:A881518F35290BAA|rigid:kNLcFGB1nOnQGr7O4/Jatl49fLg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8N7W2-2	uniprotkb:P35184	intact:EBI-10181188|ensembl:ENSP00000367868	intact:EBI-17971|uniprotkb:D6VVU2|ensemblfungi:YIR012W	psi-mi:q8n7w2-2(display_long)|uniprotkb:C10orf30(gene name synonym)|uniprotkb:BEND7(gene name)|psi-mi:BEND7(display_short)	psi-mi:sqt1_yeast(display_long)|uniprotkb:YIB12W(orf name)|uniprotkb:YIR012W(locus name)|uniprotkb:SQT1(gene name)|psi-mi:SQT1(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11556572|imex:IM-24995-4530	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000165626(gene)|ensembl:ENST00000378605(transcript)|intact:EBI-743382(isoform-parent)|uniprotkb:Q8N7W2-2(isoform-parent)|entrezgene/locuslink:222389(identity)	refseq:NP_012277.1|sgd:S000001451|ensemblfungi:YIR012W_mRNA(transcript)|ensemblfungi:YIR012W(gene)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|rcsb pdb:4ZOV|rcsb pdb:4ZOX|rcsb pdb:5AMS|dip:DIP-2508N|mint:P35184|sgd:YIR012W(identity)	-	-	crc64:981D566076B0C881	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:p6qrTn80hLyVU0W2Tvwn50Q4m5I9606	rogid:u/Q5uAjR85ZD3op0nHiN20IVCLY559292	intact-crc:C87899C43DA33687|rigid:toOVjX2vGMz6qqn4DYa1Ab6pYvg	false	sufficient binding region:10-374	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P35192	uniprotkb:Q8N9N5-2	intact:EBI-10346|ensemblfungi:YMR021C|uniprotkb:D6VZJ5|uniprotkb:E9P8Z5	intact:EBI-11524452|ensembl:ENSP00000347125	psi-mi:mac1_yeast(display_long)|uniprotkb:MAC1(gene name)|psi-mi:MAC1(display_short)|uniprotkb:CUA1(gene name synonym)|uniprotkb:YMR021C(locus name)|uniprotkb:YM9711.11C(orf name)	psi-mi:q8n9n5-2(display_long)|uniprotkb:BANP(gene name)|psi-mi:BANP(display_short)|uniprotkb:BEN domain-containing protein 1(gene name synonym)|uniprotkb:BEND1(gene name synonym)|uniprotkb:Btg3-associated nuclear protein(gene name synonym)|uniprotkb:SMAR1(gene name synonym)|uniprotkb:Scaffold/matrix-associated region-1-binding protein(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11556648|imex:IM-24995-4538	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013734.1|sgd:S000004623|ensemblfungi:YMR021C(gene)|ensemblfungi:YMR021C_mRNA(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005507"(copper ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0006878"(cellular copper ion homeostasis)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR036395|interpro:IPR001083(Copper fist DNA-binding)|dip:DIP-4851N|sgd:YMR021C(identity)	ensembl:ENSG00000172530(gene)|ensembl:ENST00000355022(transcript)|intact:EBI-744695(isoform-parent)|uniprotkb:Q8N9N5-2(isoform-parent)|entrezgene/locuslink:54971(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:qm/hIB5eRjjEZv9H+Zng34N5ops559292	rogid:ESe6iCAhvq+i57fQHz3rGyg6UOo9606	intact-crc:1282246C4D6BD8BB|rigid:Ton7BCxl/TrkXRCpHGyZ531A/dM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P63279	uniprotkb:P35192	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	intact:EBI-10346|ensemblfungi:YMR021C|uniprotkb:D6VZJ5|uniprotkb:E9P8Z5	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:mac1_yeast(display_long)|uniprotkb:MAC1(gene name)|psi-mi:MAC1(display_short)|uniprotkb:CUA1(gene name synonym)|uniprotkb:YMR021C(locus name)|uniprotkb:YM9711.11C(orf name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11556639|imex:IM-24995-4537	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N|entrezgene/locuslink:7329(identity)	refseq:NP_013734.1|sgd:S000004623|ensemblfungi:YMR021C(gene)|ensemblfungi:YMR021C_mRNA(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005507"(copper ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0006878"(cellular copper ion homeostasis)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR036395|interpro:IPR001083(Copper fist DNA-binding)|dip:DIP-4851N|sgd:YMR021C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	rogid:qm/hIB5eRjjEZv9H+Zng34N5ops559292	intact-crc:987D3EE8FDD63FC4|rigid:FKAl0qhsW7XehKRyWFSuNYvGXFk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:A0A024R4Q5	uniprotkb:P35719	intact:EBI-11527449	intact:EBI-16255|ensemblfungi:YKL142W|uniprotkb:D6VX54	psi-mi:a0a024r4q5_human(display_long)|uniprotkb:hCG_20946(orf name)|uniprotkb:TFPT(gene name)|psi-mi:TFPT(display_short)	psi-mi:mrp8_yeast(display_long)|uniprotkb:MRP8(gene name)|psi-mi:MRP8(display_short)|uniprotkb:YKL3(orf name)|uniprotkb:YKL142W(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11556657|imex:IM-24995-4539	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_037474.1|interpro:IPR033555|go:"GO:0005654"(nucleoplasm)|go:"GO:0006915"(apoptotic process)|entrezgene/locuslink:29844(identity)	refseq:NP_012780.1|sgd:S000001625|ensemblfungi:YKL142W(gene)|go:"GO:0005737"(cytoplasm)|interpro:IPR012917(Ribosomal protein MRP8, mitochondrial)|ensemblfungi:YKL142W_mRNA(transcript)|dip:DIP-1437N|mint:P35719|sgd:YKL142W(identity)	-	-	crc64:CCAD54B7581A5ABE	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:juI/3gZemjc0hnXDJ9J+bIQ9pBw9606	rogid:xrv86SZgOYjf+CaLkNdme45DC9s559292	intact-crc:FCB53478C5EF2676|rigid:t2kvQdRlFcuC5B3VyNAvAD0B5P0	false	sufficient binding region:10-253	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9NSC5	uniprotkb:P35191	intact:EBI-748420|uniprotkb:O14580|uniprotkb:O95350|uniprotkb:Q9NSB9|uniprotkb:Q9NSC0|intact:EBI-2557809|uniprotkb:E9PCW9|uniprotkb:Q9NSC1|intact:EBI-28972925|ensembl:ENSP00000376162|ensembl:ENSP00000439937|ensembl:ENSP00000446026|intact:EBI-10175777|uniprotkb:B2RA10	intact:EBI-10603|ensemblfungi:YFL016C|uniprotkb:D6VTL4	psi-mi:home3_human(display_long)|uniprotkb:HOMER3(gene name)|psi-mi:HOMER3(display_short)	psi-mi:mdj1_yeast(display_long)|uniprotkb:YFL016C(locus name)|uniprotkb:MDJ1(gene name)|psi-mi:MDJ1(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11556630|imex:IM-24995-4536	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000221222|ensembl:ENSP00000221222|ensembl:ENSP00000376162|ensembl:ENST00000433218|ensembl:ENSP00000396154|ensembl:ENSP00000439937|ensembl:ENSP00000446026|ensembl:ENST00000594439|ensembl:ENSP00000471835|refseq:XP_006723006.1|refseq:XP_006723007.1|refseq:NP_001139193.1|refseq:NP_001139194.1|refseq:NP_004829.3|refseq:NP_001139196.1|ensembl:ENSG00000051128(gene)|ensembl:ENST00000392351(transcript)|ensembl:ENST00000539827(transcript)|ensembl:ENST00000542541(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006605"(protein targeting)|go:"GO:0007216"(G protein-coupled glutamate receptor signaling pathway)|go:"GO:0014069"(postsynaptic density)|go:"GO:0030425"(dendrite)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0035256"(G protein-coupled glutamate receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|go:"GO:2001256"(regulation of store-operated calcium entry)|interpro:IPR000697(EVH1)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR044100|mint:Q9NSC5|rcsb pdb:2P8V|rcsb pdb:3CVF|reactome:R-HSA-6794361|entrezgene/locuslink:9454(identity)	ensemblfungi:YFL016C(gene)|ensemblfungi:YFL016C_mRNA(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0009408"(response to heat)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031314"(extrinsic component of mitochondrial inner membrane)|go:"GO:0042026"(protein refolding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|interpro:IPR001305(Heat shock protein DnaJ, cysteine-rich region)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR012724(Chaperone DnaJ)|interpro:IPR018253|interpro:IPR036410|interpro:IPR036869|go:"GO:0005759"(mitochondrial matrix)|refseq:NP_116638.1|sgd:S000001878|mint:P35191|dip:DIP-764N|sgd:YFL016C(identity)	-	-	crc64:007343427C66D2B6	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:U1y/y52nnf7zQUCNQlqk7JDgXi49606	rogid:2JbQztkUZ2kj7Y45Ghq1vTAhYdU559292	intact-crc:EFD6B7545576DEEB|rigid:bMATE5CfS2vO46/cf0YpYoWM7VY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UJV3-2	uniprotkb:P35184	intact:EBI-10172526|ensembl:ENSP00000413976	intact:EBI-17971|uniprotkb:D6VVU2|ensemblfungi:YIR012W	psi-mi:q9ujv3-2(display_long)|uniprotkb:RING-type E3 ubiquitin transferase MID2(gene name synonym)|uniprotkb:FXY2(gene name synonym)|uniprotkb:Midin-2(gene name synonym)|uniprotkb:Midline defect 2(gene name synonym)|uniprotkb:Midline-2(gene name synonym)|uniprotkb:RING finger protein 60(gene name synonym)|uniprotkb:RNF60(gene name synonym)|uniprotkb:TRIM1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 1(gene name synonym)|uniprotkb:MID2(gene name)|psi-mi:MID2(display_short)	psi-mi:sqt1_yeast(display_long)|uniprotkb:YIB12W(orf name)|uniprotkb:YIR012W(locus name)|uniprotkb:SQT1(gene name)|psi-mi:SQT1(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11556619|imex:IM-24995-4535	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-751983(isoform-parent)|uniprotkb:Q9UJV3-2(isoform-parent)|ensembl:ENSG00000080561(gene)|ensembl:ENST00000443968(transcript)|entrezgene/locuslink:11043(identity)	refseq:NP_012277.1|sgd:S000001451|ensemblfungi:YIR012W_mRNA(transcript)|ensemblfungi:YIR012W(gene)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|rcsb pdb:4ZOV|rcsb pdb:4ZOX|rcsb pdb:5AMS|dip:DIP-2508N|mint:P35184|sgd:YIR012W(identity)	-	-	crc64:981D566076B0C881	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:/FJ+V2H7SaWon7caUWkEkmHFVxQ9606	rogid:u/Q5uAjR85ZD3op0nHiN20IVCLY559292	intact-crc:D7BBD60B834B4BC0|rigid:SKAxlSi558MbzGjE3wZvuhoaL34	false	sufficient binding region:21-705	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q13422-7	uniprotkb:P36009	intact:EBI-11522367|ensembl:ENSP00000352123|ensembl:ENSP00000413025	intact:EBI-5844|ensemblfungi:YKL078W|uniprotkb:Q07040|uniprotkb:D6VXK9	psi-mi:q13422-7(display_long)|uniprotkb:IKZF1(gene name)|psi-mi:IKZF1(display_short)|uniprotkb:IK1(gene name synonym)|uniprotkb:IKAROS(gene name synonym)|uniprotkb:Ikaros family zinc finger protein 1(gene name synonym)|uniprotkb:LYF1(gene name synonym)|uniprotkb:Lymphoid transcription factor LyF-1(gene name synonym)|uniprotkb:ZNFN1A1(gene name synonym)	psi-mi:dhr2_yeast(display_long)|uniprotkb:DHR2(gene name)|psi-mi:DHR2(display_short)|uniprotkb:YKL078W(locus name)|uniprotkb:YKL408(orf name)|uniprotkb:DEAH box RNA helicase DHR2(gene name synonym)|uniprotkb:Helicase JA2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11556704|imex:IM-24995-4544	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-745305(isoform-parent)|ensembl:ENSG00000185811(gene)|ensembl:ENST00000359197(transcript)|ensembl:ENST00000439701(transcript)|uniprotkb:Q13422-7(isoform-parent)|entrezgene/locuslink:10320(identity)	ensemblfungi:YKL078W(gene)|ensemblfungi:YKL078W_mRNA(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|refseq:NP_012845.1|sgd:S000001561|dip:DIP-6424N|mint:P36009|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|sgd:YKL078W(identity)	-	-	crc64:AAFA78B5F6215D89	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:ou/ovXYoMneBNVp4pj38VxenfyY9606	rogid:UneKv9+4eIsC09fOzm8AvKCOCVs559292	intact-crc:4569A414D4B63A18|rigid:FDHu/DRyfeVGom6qYipoARsDdRE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P19012	uniprotkb:P36009	intact:EBI-739566|uniprotkb:Q53XV8|uniprotkb:Q9BUG4|uniprotkb:B3KQY1|uniprotkb:B3KRA2|uniprotkb:E0CX14|ensembl:ENSP00000254043|ensembl:ENSP00000377546	intact:EBI-5844|ensemblfungi:YKL078W|uniprotkb:Q07040|uniprotkb:D6VXK9	psi-mi:k1c15_human(display_long)|uniprotkb:KRT15(gene name)|psi-mi:KRT15(display_short)|uniprotkb:KRTB(gene name synonym)|uniprotkb:Cytokeratin-15(gene name synonym)|uniprotkb:Keratin-15(gene name synonym)	psi-mi:dhr2_yeast(display_long)|uniprotkb:DHR2(gene name)|psi-mi:DHR2(display_short)|uniprotkb:YKL078W(locus name)|uniprotkb:YKL408(orf name)|uniprotkb:DEAH box RNA helicase DHR2(gene name synonym)|uniprotkb:Helicase JA2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11556695|imex:IM-24995-4543	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002266.2|ensembl:ENSG00000171346(gene)|ensembl:ENST00000254043(transcript)|ensembl:ENST00000393976(transcript)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0008544"(epidermis development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097110"(scaffold protein binding)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR039008|mint:P19012|reactome:R-HSA-6805567|reactome:R-HSA-6809371|entrezgene/locuslink:3866(identity)	ensemblfungi:YKL078W(gene)|ensemblfungi:YKL078W_mRNA(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|refseq:NP_012845.1|sgd:S000001561|dip:DIP-6424N|mint:P36009|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|sgd:YKL078W(identity)	-	-	crc64:AAFA78B5F6215D89	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:WrZQBYQvrWcfrR5ojWXrXp6spPE9606	rogid:UneKv9+4eIsC09fOzm8AvKCOCVs559292	intact-crc:E8E708BAC2CFA4E1|rigid:NaREkejE2qJ2se3b6PCZiveu60Q	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P36001	uniprotkb:Q969G2	intact:EBI-2083615|uniprotkb:D6VX64|ensemblfungi:YKL132C	intact:EBI-2865388|uniprotkb:Q8NHM1|uniprotkb:Q969W2|uniprotkb:Q8TCJ1|uniprotkb:Q8NHE0|uniprotkb:Q8WWX2|ensembl:ENSP00000263726	psi-mi:folc_yeast(display_long)|uniprotkb:RMA1(gene name)|psi-mi:RMA1(display_short)|uniprotkb:Folylpoly-gamma-glutamate synthetase(gene name synonym)|uniprotkb:Tetrahydrofolylpolyglutamate synthase(gene name synonym)|uniprotkb:YKL132C(locus name)	psi-mi:lhx4_human(display_long)|uniprotkb:LHX4(gene name)|psi-mi:LHX4(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11556686|imex:IM-24995-4542	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012790.1|sgd:S000001615|interpro:IPR001645(Folylpolyglutamate synthetase)|interpro:IPR018109|mint:P36001|interpro:IPR036565|interpro:IPR036615|ensemblfungi:YKL132C(gene)|ensemblfungi:YKL132C_mRNA(transcript)|go:"GO:0004326"(tetrahydrofolylpolyglutamate synthase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0008841"(dihydrofolate synthase activity)|go:"GO:0009396"(folic acid-containing compound biosynthetic process)|go:"GO:0016881"(acid-amino acid ligase activity)|go:"GO:0046872"(metal ion binding)|sgd:YKL132C(identity)	refseq:NP_203129.1|dip:DIP-29454N|ensembl:ENSG00000121454(gene)|ensembl:ENST00000263726(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001890"(placenta development)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0021526"(medial motor column neuron differentiation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|mint:Q969G2|rcsb pdb:5HOD|reactome:R-HSA-9010553|entrezgene/locuslink:89884(identity)	-	-	crc64:6499F38E78B79FD1	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:pL0jH0sRdb39RE+KmXGMCnXkFZw559292	rogid:dCB3WgIBMdi0nNvaCFaioh+F9sw9606	intact-crc:37E8354BA6429E07|rigid:ojXQqv3rN6YPRhA+cjelvDLhNDo	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P35719	uniprotkb:P07954	intact:EBI-16255|ensemblfungi:YKL142W|uniprotkb:D6VX54	intact:EBI-1050358|uniprotkb:B1ANK7|ensembl:ENSP00000355518	psi-mi:mrp8_yeast(display_long)|uniprotkb:MRP8(gene name)|psi-mi:MRP8(display_short)|uniprotkb:YKL3(orf name)|uniprotkb:YKL142W(locus name)	psi-mi:fumh_human(display_long)|uniprotkb:FH(gene name)|psi-mi:FH(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11556677|imex:IM-24995-4541	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012780.1|sgd:S000001625|ensemblfungi:YKL142W(gene)|go:"GO:0005737"(cytoplasm)|interpro:IPR012917(Ribosomal protein MRP8, mitochondrial)|ensemblfungi:YKL142W_mRNA(transcript)|dip:DIP-1437N|mint:P35719|sgd:YKL142W(identity)	refseq:NP_000134.2|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006106"(fumarate metabolic process)|go:"GO:0006108"(malate metabolic process)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042393"(histone binding)|go:"GO:0045239"(tricarboxylic acid cycle enzyme complex)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0070062"(extracellular exosome)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR000362(Fumarate lyase)|interpro:IPR005677(Fumarate hydratase, class II)|ensembl:ENSG00000091483(gene)|interpro:IPR008948(L-Aspartase-like)|interpro:IPR018951|ensembl:ENST00000366560(transcript)|interpro:IPR020557|interpro:IPR022761|go:"GO:0000050"(urea cycle)|interpro:IPR024083|mint:P07954|rcsb pdb:3E04|go:"GO:0000415"(negative regulation of histone H3-K36 methylation)|rcsb pdb:5D6B|go:"GO:0000821"(regulation of arginine metabolic process)|rcsb pdb:5UPP|rcsb pdb:6EBT|rcsb pdb:6V8F|rcsb pdb:6VBE|go:"GO:0004333"(fumarate hydratase activity)|reactome:R-HSA-71403|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|dip:DIP-46920N|entrezgene/locuslink:2271(identity)	-	crc64:CCAD54B7581A5ABE	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:xrv86SZgOYjf+CaLkNdme45DC9s559292	rogid:Jukx6wt0vi49nxgaTzdz5x1Q2Mc9606	intact-crc:27306CAD300E6E8F|rigid:quZA2L8oYW5/rFS9odvmcSs3UZc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P35719	uniprotkb:O95273	intact:EBI-16255|ensemblfungi:YKL142W|uniprotkb:D6VX54	intact:EBI-748961|uniprotkb:A8K3Q0|uniprotkb:A8K3U2|uniprotkb:Q6ZQN9|uniprotkb:Q7Z519|uniprotkb:Q8NBS7|uniprotkb:Q8NBY2|uniprotkb:Q9NS19|uniprotkb:Q9NYH3|uniprotkb:Q9UHX9|ensembl:ENSP00000300213	psi-mi:mrp8_yeast(display_long)|uniprotkb:MRP8(gene name)|psi-mi:MRP8(display_short)|uniprotkb:YKL3(orf name)|uniprotkb:YKL142W(locus name)	psi-mi:ccdb1_human(display_long)|uniprotkb:Grap2 and cyclin-D-interacting protein(gene name synonym)|uniprotkb:Human homolog of Maid(gene name synonym)|uniprotkb:CCNDBP1(gene name)|psi-mi:CCNDBP1(display_short)|uniprotkb:DIP1(gene name synonym)|uniprotkb:GCIP(gene name synonym)|uniprotkb:HHM(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11556668|imex:IM-24995-4540	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012780.1|sgd:S000001625|ensemblfungi:YKL142W(gene)|go:"GO:0005737"(cytoplasm)|interpro:IPR012917(Ribosomal protein MRP8, mitochondrial)|ensemblfungi:YKL142W_mRNA(transcript)|dip:DIP-1437N|mint:P35719|sgd:YKL142W(identity)	refseq:NP_036274.3|ensembl:ENSG00000166946(gene)|ensembl:ENST00000300213(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0016604"(nuclear body)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR026907|mint:O95273|rcsb pdb:3AY5|entrezgene/locuslink:23582(identity)	-	crc64:CCAD54B7581A5ABE	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:xrv86SZgOYjf+CaLkNdme45DC9s559292	rogid:Vi9aoFc+Mov6P3X6KGmsTxXqxvM9606	intact-crc:5A60D196DB739142|rigid:4erpV7VkNjR/NOhLjNIqNdj0S1g	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P36084	uniprotkb:Q08379	intact:EBI-11612|ensemblfungi:YKL074C|uniprotkb:D6VXL2	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	psi-mi:mud2_yeast(display_long)|uniprotkb:MUD2(gene name)|psi-mi:MUD2(display_short)|uniprotkb:YKL358(orf name)|uniprotkb:YKL074C(locus name)	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11556767|imex:IM-24995-4551	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0000243"(commitment complex)|go:"GO:0000348"(mRNA branch site recognition)|go:"GO:0003729"(mRNA binding)|go:"GO:0008187"(poly-pyrimidine tract binding)|go:"GO:0016607"(nuclear speck)|ensemblfungi:YKL074C(gene)|go:"GO:0030628"(pre-mRNA 3'-splice site binding)|go:"GO:0045131"(pre-mRNA branch point binding)|go:"GO:0071004"(U2-type prespliceosome)|ensemblfungi:YKL074C_mRNA(transcript)|go:"GO:0089701"(U2AF complex)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|refseq:NP_012849.1|sgd:S000001557|mint:P36084|dip:DIP-758N|sgd:YKL074C(identity)	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N|entrezgene/locuslink:2801(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2017/05/26	rogid:l/aBULMxdezuufNxUE5qqnYEN1Y559292	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	intact-crc:24DAE647192BD37F|rigid:GOJOGcJuewHTPD3FhWtNjgReEgU	false	-	sufficient binding region:383-1002	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P36084	uniprotkb:Q8N5R6	intact:EBI-11612|ensemblfungi:YKL074C|uniprotkb:D6VXL2	intact:EBI-740841|intact:EBI-953781|uniprotkb:B3KQ49|uniprotkb:A8K3U4|uniprotkb:A8MPQ6|uniprotkb:A8MV61|uniprotkb:A8MVU9|uniprotkb:Q9H5Q6|uniprotkb:Q8TAX6|intact:EBI-2320546|intact:EBI-11522976	psi-mi:mud2_yeast(display_long)|uniprotkb:MUD2(gene name)|psi-mi:MUD2(display_short)|uniprotkb:YKL358(orf name)|uniprotkb:YKL074C(locus name)	psi-mi:ccd33_human(display_long)|uniprotkb:CCDC33(gene name)|psi-mi:CCDC33(display_short)|uniprotkb:Cancer/testis antigen 61(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11556758|imex:IM-24995-4550	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0000243"(commitment complex)|go:"GO:0000348"(mRNA branch site recognition)|go:"GO:0003729"(mRNA binding)|go:"GO:0008187"(poly-pyrimidine tract binding)|go:"GO:0016607"(nuclear speck)|ensemblfungi:YKL074C(gene)|go:"GO:0030628"(pre-mRNA 3'-splice site binding)|go:"GO:0045131"(pre-mRNA branch point binding)|go:"GO:0071004"(U2-type prespliceosome)|ensemblfungi:YKL074C_mRNA(transcript)|go:"GO:0089701"(U2AF complex)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|refseq:NP_012849.1|sgd:S000001557|mint:P36084|dip:DIP-758N|sgd:YKL074C(identity)	refseq:NP_079331.3|interpro:IPR000008(C2 calcium-dependent membrane targeting)|go:"GO:0005777"(peroxisome)|refseq:NP_001274110.1|refseq:NP_877592.2|mint:Q8N5R6|interpro:IPR035892|interpro:IPR039889|entrezgene/locuslink:80125(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2021/11/30	rogid:l/aBULMxdezuufNxUE5qqnYEN1Y559292	rogid:eEIn7pQyfdHWx8TeLJpYy0i/gww9606	intact-crc:29F583912C7AB823|rigid:9jA2zOpeNU+zSpP2ttF0RE5qAYg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P36057	uniprotkb:O43765	intact:EBI-18091|uniprotkb:D6VX44|ensemblfungi:YKL154W	intact:EBI-347996|ensembl:ENSP00000221566|ensembl:ENSP00000503397|ensembl:ENSP00000504495|uniprotkb:Q9BTZ9|intact:EBI-1045243|uniprotkb:Q6FIA9|uniprotkb:D6W610	psi-mi:srpb_yeast(display_long)|uniprotkb:SRP102(gene name)|psi-mi:SRP102(display_short)|uniprotkb:YKL609(orf name)|uniprotkb:YKL154W(locus name)	psi-mi:sgta_human(display_long)|uniprotkb:SGTA(gene name)|psi-mi:SGTA(display_short)|uniprotkb:SGT(gene name synonym)|uniprotkb:Alpha-SGT(gene name synonym)|uniprotkb:Vpu-binding protein(gene name synonym)|uniprotkb:SGT1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11556749|imex:IM-24995-4549	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012768.1|sgd:S000001637|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045047"(protein targeting to ER)|interpro:IPR019009|interpro:IPR027417|rcsb pdb:1NRJ|rcsb pdb:2GED|ensemblfungi:YKL154W(gene)|ensemblfungi:YKL154W_mRNA(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005047"(signal recognition particle binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005785"(signal recognition particle receptor complex)|dip:DIP-4753N|sgd:YKL154W(identity)	rcsb pdb:4CPG|rcsb pdb:4GOD|rcsb pdb:4GOE|rcsb pdb:4GOF|reactome:R-HSA-9609523|rcsb pdb:2VYI|ensembl:ENSG00000104969(gene)|ensembl:ENST00000221566(transcript)|ensembl:ENST00000676943(transcript)|ensembl:ENST00000677149(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072380"(TRC complex)|go:"GO:0098850"(extrinsic component of synaptic vesicle membrane)|go:"GO:1903070"(negative regulation of ER-associated ubiquitin-dependent protein catabolic process)|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)|go:"GO:1903646"(positive regulation of chaperone-mediated protein folding)|go:"GO:1904288"(BAT3 complex binding)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR032374|mint:O43765|refseq:XP_011526480.1|refseq:NP_003012.1|entrezgene/locuslink:6449(identity)	-	crc64:EA4AE9126B2A04B5	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:PWBNmZgucFpCtOusxQ3OU1ZvAQ4559292	rogid:r/Cyj4UJk/cS8QdrbjhTZMPCigI9606	intact-crc:FB814A427FEB2CC2|rigid:5IGU5+F3p/NfHYJeS33OkYCUrb8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8NEU8	uniprotkb:P36019	intact:EBI-741261|ensembl:ENSP00000258530|uniprotkb:Q8N4R7|uniprotkb:Q9NVL2|uniprotkb:B7Z411|uniprotkb:B7Z4B0|uniprotkb:F5GZG0|uniprotkb:F8W1P5	intact:EBI-29415|uniprotkb:Q45TZ5|uniprotkb:D6W187|ensemblfungi:YNL093W	psi-mi:dp13b_human(display_long)|uniprotkb:Adapter protein containing PH domain, PTB domain and leucine zipper motif 2(gene name synonym)|uniprotkb:APPL2(gene name)|psi-mi:APPL2(display_short)|uniprotkb:DIP13B(gene name synonym)	psi-mi:ypt53_yeast(display_long)|uniprotkb:YPT53(gene name)|psi-mi:YPT53(display_short)|uniprotkb:N2223(orf name)|uniprotkb:YNL093W(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11556740|imex:IM-24995-4548	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0002024"(diet induced thermogenesis)|go:"GO:0005634"(nucleus)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0009631"(cold acclimation)|go:"GO:0010008"(endosome membrane)|go:"GO:0010762"(regulation of fibroblast migration)|go:"GO:0016020"(membrane)|go:"GO:0023052"(signaling)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032009"(early phagosome)|go:"GO:0032587"(ruffle membrane)|go:"GO:0033211"(adiponectin-activated signaling pathway)|go:"GO:0034143"(regulation of toll-like receptor 4 signaling pathway)|go:"GO:0035091"(phosphatidylinositol binding)|ensembl:ENSG00000136044(gene)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0036186"(early phagosome membrane)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|ensembl:ENST00000258530(transcript)|go:"GO:0044354"(macropinosome)|go:"GO:0001726"(ruffle)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000178"(negative regulation of neural precursor cell proliferation)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR027267|mint:Q8NEU8|rcsb pdb:4H8S|rcsb pdb:5C5B|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0046322"(negative regulation of fatty acid oxidation)|go:"GO:0046325"(negative regulation of glucose import)|go:"GO:0050768"(negative regulation of neurogenesis)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060100"(positive regulation of phagocytosis, engulfment)|go:"GO:0070062"(extracellular exosome)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1900016"(negative regulation of cytokine production involved in inflammatory response)|go:"GO:1900077"(negative regulation of cellular response to insulin stimulus)|go:"GO:1905303"(positive regulation of macropinocytosis)|go:"GO:1905451"(positive regulation of Fc-gamma receptor signaling pathway involved in phagocytosis)|refseq:NP_060641.2|refseq:XP_016875042.1|refseq:XP_016875041.1|refseq:NP_001238833.1|refseq:NP_001238834.1|entrezgene/locuslink:55198(identity)	sgd:S000005037|refseq:NP_014306.3|dip:DIP-2025N|ensemblfungi:YNL093W(gene)|ensemblfungi:YNL093W_mRNA(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0006897"(endocytosis)|go:"GO:0012505"(endomembrane system)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|sgd:YNL093W(identity)	-	-	crc64:ABA1D926D1EE9F68	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:8T+Y5phqYZ2On/CsfVVsOChSJNM9606	rogid:2IDdF9ESvaxekyjmAzuRL9vMYJ8559292	intact-crc:EA9F175D6DA0EBD2|rigid:Vsh+AYUv89QAliyy3oxOk5Jo9I0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P36019	uniprotkb:Q8N612	intact:EBI-29415|uniprotkb:Q45TZ5|uniprotkb:D6W187|ensemblfungi:YNL093W	intact:EBI-742137|uniprotkb:Q9C0A4|uniprotkb:Q9H0N3|uniprotkb:Q9H624|intact:EBI-28987623|ensembl:ENSP00000416918	psi-mi:ypt53_yeast(display_long)|uniprotkb:YPT53(gene name)|psi-mi:YPT53(display_short)|uniprotkb:N2223(orf name)|uniprotkb:YNL093W(locus name)	psi-mi:fhi1b_human(display_long)|uniprotkb:FHIP1B(gene name)|psi-mi:FHIP1B(display_short)|uniprotkb:C11orf56(gene name synonym)|uniprotkb:FAM160A2(gene name synonym)|uniprotkb:FTS and Hook-interacting protein(gene name synonym)|uniprotkb:KIAA1759(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11556731|imex:IM-24995-4547	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005037|refseq:NP_014306.3|dip:DIP-2025N|ensemblfungi:YNL093W(gene)|ensemblfungi:YNL093W_mRNA(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0006897"(endocytosis)|go:"GO:0012505"(endomembrane system)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|sgd:YNL093W(identity)	refseq:NP_001092264.1|refseq:NP_115503.2|refseq:XP_011518699.1|ensembl:ENST00000265978|ensembl:ENSP00000265978|ensembl:ENSP00000416918|refseq:XP_006718406.1|ensembl:ENSG00000051009(gene)|ensembl:ENST00000449352(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0007032"(endosome organization)|go:"GO:0007040"(lysosome organization)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0015031"(protein transport)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0070695"(FHF complex)|go:"GO:1905719"(protein localization to perinuclear region of cytoplasm)|interpro:IPR019384|entrezgene/locuslink:84067(identity)	-	crc64:ABA1D926D1EE9F68	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:2IDdF9ESvaxekyjmAzuRL9vMYJ8559292	rogid:sHMptILNXi94k81XAjE55r829C49606	intact-crc:E9C82A0CDABACD20|rigid:LJcwCYkDrCltO+woa97BRuKD/8U	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P36018	uniprotkb:Q8NEU8	intact:EBI-29407|uniprotkb:D6VX79|ensemblfungi:YKR014C	intact:EBI-741261|ensembl:ENSP00000258530|uniprotkb:Q8N4R7|uniprotkb:Q9NVL2|uniprotkb:B7Z411|uniprotkb:B7Z4B0|uniprotkb:F5GZG0|uniprotkb:F8W1P5	psi-mi:ypt52_yeast(display_long)|uniprotkb:YPT52(gene name)|psi-mi:YPT52(display_short)|uniprotkb:YK112(orf name)|uniprotkb:YKR014C(locus name)	psi-mi:dp13b_human(display_long)|uniprotkb:Adapter protein containing PH domain, PTB domain and leucine zipper motif 2(gene name synonym)|uniprotkb:APPL2(gene name)|psi-mi:APPL2(display_short)|uniprotkb:DIP13B(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11556722|imex:IM-24995-4546	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012939.1|sgd:S000001722|dip:DIP-2121N|mint:P36018|ensemblfungi:YKR014C(gene)|ensemblfungi:YKR014C_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0006897"(endocytosis)|go:"GO:0012505"(endomembrane system)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0036258"(multivesicular body assembly)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|reactome:R-SCE-6798695|reactome:R-SCE-8856828|reactome:R-SCE-8873719|reactome:R-SCE-8876198|reactome:R-SCE-983231|sgd:YKR014C(identity)	go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0002024"(diet induced thermogenesis)|go:"GO:0005634"(nucleus)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0009631"(cold acclimation)|go:"GO:0010008"(endosome membrane)|go:"GO:0010762"(regulation of fibroblast migration)|go:"GO:0016020"(membrane)|go:"GO:0023052"(signaling)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032009"(early phagosome)|go:"GO:0032587"(ruffle membrane)|go:"GO:0033211"(adiponectin-activated signaling pathway)|go:"GO:0034143"(regulation of toll-like receptor 4 signaling pathway)|go:"GO:0035091"(phosphatidylinositol binding)|ensembl:ENSG00000136044(gene)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0036186"(early phagosome membrane)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|ensembl:ENST00000258530(transcript)|go:"GO:0044354"(macropinosome)|go:"GO:0001726"(ruffle)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000178"(negative regulation of neural precursor cell proliferation)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR027267|mint:Q8NEU8|rcsb pdb:4H8S|rcsb pdb:5C5B|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0046322"(negative regulation of fatty acid oxidation)|go:"GO:0046325"(negative regulation of glucose import)|go:"GO:0050768"(negative regulation of neurogenesis)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060100"(positive regulation of phagocytosis, engulfment)|go:"GO:0070062"(extracellular exosome)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1900016"(negative regulation of cytokine production involved in inflammatory response)|go:"GO:1900077"(negative regulation of cellular response to insulin stimulus)|go:"GO:1905303"(positive regulation of macropinocytosis)|go:"GO:1905451"(positive regulation of Fc-gamma receptor signaling pathway involved in phagocytosis)|refseq:NP_060641.2|refseq:XP_016875042.1|refseq:XP_016875041.1|refseq:NP_001238833.1|refseq:NP_001238834.1|entrezgene/locuslink:55198(identity)	-	crc64:34AB2FFE38697261	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:KZ9/F9Ilto2oDHiPHffIM2gcVnY559292	rogid:8T+Y5phqYZ2On/CsfVVsOChSJNM9606	intact-crc:86D14F7624160F00|rigid:lHzj+ZFvH2+kCKWOePtCz1O1SO8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P36009	uniprotkb:Q96BR9	intact:EBI-5844|ensemblfungi:YKL078W|uniprotkb:Q07040|uniprotkb:D6VXK9	intact:EBI-742740|uniprotkb:Q8IUL5|uniprotkb:Q8IWR9|uniprotkb:Q8N2Y5|uniprotkb:Q96BX0|ensembl:ENSP00000362609	psi-mi:dhr2_yeast(display_long)|uniprotkb:DHR2(gene name)|psi-mi:DHR2(display_short)|uniprotkb:YKL078W(locus name)|uniprotkb:YKL408(orf name)|uniprotkb:DEAH box RNA helicase DHR2(gene name synonym)|uniprotkb:Helicase JA2(gene name synonym)	psi-mi:zbt8a_human(display_long)|uniprotkb:ZBTB8A(gene name)|psi-mi:ZBTB8A(display_short)|uniprotkb:BOZF1(gene name synonym)|uniprotkb:BTB/POZ and zinc-finger domain-containing factor(gene name synonym)|uniprotkb:BTB/POZ and zinc-finger domains factor on chromosome 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11556713|imex:IM-24995-4545	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YKL078W(gene)|ensemblfungi:YKL078W_mRNA(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|refseq:NP_012845.1|sgd:S000001561|dip:DIP-6424N|mint:P36009|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|sgd:YKL078W(identity)	ensembl:ENSG00000160062(gene)|ensembl:ENST00000373510(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|refseq:NP_001035531.2|refseq:NP_001278425.1|entrezgene/locuslink:653121(identity)	-	crc64:AAFA78B5F6215D89	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:UneKv9+4eIsC09fOzm8AvKCOCVs559292	rogid:tsrPT2tHvuBryODKgRXnceXz9s09606	intact-crc:A7E4C470BC4BB20E|rigid:WbBEdlgDyAgMyDVt3Br/S+A2t+E	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P36125	uniprotkb:Q15437	intact:EBI-26378|uniprotkb:D6VX95|ensemblfungi:YKR030W	intact:EBI-742673|uniprotkb:Q5W183|uniprotkb:Q9BS15|uniprotkb:Q9BSI2|uniprotkb:Q9H1D7|intact:EBI-1048165|uniprotkb:Q503A9|uniprotkb:D3DW33|ensembl:ENSP00000262544|ensembl:ENSP00000338844|ensembl:ENSP00000366685|ensembl:ENSP00000497473	psi-mi:gmh1_yeast(display_long)|uniprotkb:YKR030W(locus name)|uniprotkb:GEA1-6 membrane-associated high-copy suppressor protein 1(gene name synonym)|uniprotkb:GMH1(gene name)|psi-mi:GMH1(display_short)|uniprotkb:MSG1(gene name synonym)	psi-mi:sc23b_human(display_long)|uniprotkb:SEC23-related protein B(gene name synonym)|uniprotkb:SEC23B(gene name)|psi-mi:SEC23B(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11556832|imex:IM-24995-4558	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012955.1|sgd:S000001738|mint:P36125|dip:DIP-2023N|ensemblfungi:YKR030W(gene)|ensemblfungi:YKR030W_mRNA(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030173"(integral component of Golgi membrane)|interpro:IPR007881(UNC-50)|sgd:YKR030W(identity)	refseq:NP_001166216.1|refseq:NP_006354.2|refseq:NP_116780.1|refseq:NP_116781.1|ensembl:ENSG00000101310(gene)|ensembl:ENST00000262544(transcript)|ensembl:ENST00000336714(transcript)|ensembl:ENST00000377465(transcript)|ensembl:ENST00000650089(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008270"(zinc ion binding)|go:"GO:0012505"(endomembrane system)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0090110"(COPII-coated vesicle cargo loading)|go:"GO:0070971"(endoplasmic reticulum exit site)|interpro:IPR006895(Zinc finger, Sec23/Sec24-type)|interpro:IPR006896(Sec23/Sec24 trunk region)|interpro:IPR006900(Sec23/Sec24 helical region)|interpro:IPR007123(Gelsolin region)|interpro:IPR012990(Sec23/Sec24 beta-sandwich)|interpro:IPR029006|interpro:IPR036174|interpro:IPR036175|interpro:IPR036180|interpro:IPR036465|interpro:IPR037364|interpro:IPR037550|mint:Q15437|refseq:XP_016883082.1|entrezgene/locuslink:10483(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:lmgeWk7CkMQRDAfkDOgwqC9rb/g559292	rogid:+3KZ/1jjziSgJRcr81Axquofkl49606	intact-crc:7CA26E55A274B890|rigid:DPf4M4oTuC9pt++S4M+AuOcy+zA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96BD8	uniprotkb:P36118	intact:EBI-741854|uniprotkb:B2R9Y6|uniprotkb:B4E0P4|ensembl:ENSP00000285116|ensembl:ENSP00000381470|ensembl:ENSP00000458992|ensembl:ENSP00000478259	intact:EBI-26362|uniprotkb:D6VX87|ensemblfungi:YKR022C	psi-mi:ska1_human(display_long)|uniprotkb:SKA1(gene name)|psi-mi:SKA1(display_short)|uniprotkb:C18orf24(gene name synonym)	psi-mi:ntr2_yeast(display_long)|uniprotkb:YKR022C(locus name)|uniprotkb:Nineteen complex-related protein 2(gene name synonym)|uniprotkb:NTR2(gene name)|psi-mi:NTR2(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11556823|imex:IM-24995-4557	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001034624.1|refseq:NP_659497.1|ensembl:ENSG00000154839(gene)|ensembl:ENSG00000262634(gene)|ensembl:ENST00000285116(transcript)|ensembl:ENST00000398452(transcript)|ensembl:ENST00000571751(transcript)|ensembl:ENST00000616604(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000940"(outer kinetochore)|go:"GO:0005829"(cytosol)|go:"GO:0005876"(spindle microtubule)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008017"(microtubule binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0031110"(regulation of microtubule polymerization or depolymerization)|go:"GO:0051301"(cell division)|go:"GO:0072686"(mitotic spindle)|interpro:IPR009829(Protein of unknown function DUF1395)|interpro:IPR042031|mint:Q96BD8|rcsb pdb:4AJ5|rcsb pdb:4C9Y|rcsb pdb:4CA0|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|entrezgene/locuslink:220134(identity)	sgd:S000001730|refseq:NP_012947.1|mint:P36118|dip:DIP-1924N|ensemblfungi:YKR022C(gene)|ensemblfungi:YKR022C_mRNA(transcript)|go:"GO:0000390"(spliceosomal complex disassembly)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0071008"(U2-type post-mRNA release spliceosomal complex)|interpro:IPR028211|rcsb pdb:5Y88|sgd:YKR022C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Z7y57MeLsUJK0R9JNqHJNBbKr/89606	rogid:q7LBRp/vP0mdE4MGFfqW71T1LQg559292	intact-crc:26D8875DB3B9F81E|rigid:aA8MCdVRwzodM3hsX3LdAXASxss	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P36108	uniprotkb:Q96L14	intact:EBI-26574|uniprotkb:D6VXT5|ensemblfungi:YKL002W	intact:EBI-743488	psi-mi:did4_yeast(display_long)|uniprotkb:VPL2(gene name synonym)|uniprotkb:VPS2(gene name synonym)|uniprotkb:VPT14(gene name synonym)|uniprotkb:YKL002W(locus name)|uniprotkb:DID4(gene name)|psi-mi:DID4(display_short)|uniprotkb:CHM2(gene name synonym)|uniprotkb:GRD7(gene name synonym)|uniprotkb:REN1(gene name synonym)|uniprotkb:Vacuolar protein-sorting-associated protein 2(gene name synonym)|uniprotkb:Vacuolar protein-targeting protein 14(gene name synonym)|uniprotkb:ESCRT-III complex subunit VPS2(gene name synonym)	psi-mi:c170l_human(display_long)|uniprotkb:KIAA0470L(gene name synonym)|uniprotkb:CEP170P1(gene name)|psi-mi:CEP170P1(display_short)|uniprotkb:CEP170L(gene name synonym)|uniprotkb:CEP170 pseudogene 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11556814|imex:IM-24995-4556	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012924.2|sgd:S000001485|mint:P36108|dip:DIP-1916N|ensemblfungi:YKL002W(gene)|ensemblfungi:YKL002W_mRNA(transcript)|go:"GO:0000815"(ESCRT III complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005771"(multivesicular body)|go:"GO:0015031"(protein transport)|go:"GO:0032509"(endosome transport via multivesicular body sorting pathway)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0045053"(protein retention in Golgi apparatus)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0070676"(intralumenal vesicle formation)|go:"GO:1904669"(ATP export)|interpro:IPR005024(Snf7)|rcsb pdb:2V6X|rcsb pdb:6AP1|rcsb pdb:6BMF|reactome:R-SCE-1632852|reactome:R-SCE-917729|reactome:R-SCE-9668328|sgd:YKL002W(identity)	interpro:IPR026644|interpro:IPR029300|go:"GO:0042802"(identical protein binding)|entrezgene/locuslink:645455(identity)	-	crc64:200D07DB4C45DCBC	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:iQ8lcGhal3Pt46dwcOkIW2fp/G0559292	rogid:Z/Rium0Kwj3ZUHa4WE5PPksPXdg9606	intact-crc:CD3066540407B42E|rigid:RYPdLnjN5ZPY/1MSObzNeUAzgKo	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P36086	uniprotkb:P19012	intact:EBI-2343631|uniprotkb:D6VXL5|ensemblfungi:YKL071W	intact:EBI-739566|uniprotkb:Q53XV8|uniprotkb:Q9BUG4|uniprotkb:B3KQY1|uniprotkb:B3KRA2|uniprotkb:E0CX14|ensembl:ENSP00000254043|ensembl:ENSP00000377546	psi-mi:ykh1_yeast(display_long)|uniprotkb:YKL071W(locus name)	psi-mi:k1c15_human(display_long)|uniprotkb:KRT15(gene name)|psi-mi:KRT15(display_short)|uniprotkb:KRTB(gene name synonym)|uniprotkb:Cytokeratin-15(gene name synonym)|uniprotkb:Keratin-15(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11556805|imex:IM-24995-4555	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR002347(Glucose/ribitol dehydrogenase)|refseq:NP_012852.1|sgd:S000001554|interpro:IPR036291|ensemblfungi:YKL071W(gene)|ensemblfungi:YKL071W_mRNA(transcript)|go:"GO:0004022"("alcohol dehydrogenase (NAD+) activity")|go:"GO:0005737"(cytoplasm)|go:"GO:0110095"(cellular detoxification of aldehyde)|sgd:YKL071W(identity)	refseq:NP_002266.2|ensembl:ENSG00000171346(gene)|ensembl:ENST00000254043(transcript)|ensembl:ENST00000393976(transcript)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0008544"(epidermis development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097110"(scaffold protein binding)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR039008|mint:P19012|reactome:R-HSA-6805567|reactome:R-HSA-6809371|entrezgene/locuslink:3866(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:9+aUU4I1T7cAMKJgi1qbDD4t+WM559292	rogid:WrZQBYQvrWcfrR5ojWXrXp6spPE9606	intact-crc:1483D1C88130496B|rigid:yFBCH6y2fAf8NjyZpokQqbWZ0Lk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q5VWX1	uniprotkb:P36084	intact:EBI-742808|uniprotkb:Q8TCZ4|uniprotkb:Q8N4I4|uniprotkb:A8K7M8|ensembl:ENSP00000281156	intact:EBI-11612|ensemblfungi:YKL074C|uniprotkb:D6VXL2	psi-mi:khdr2_human(display_long)|uniprotkb:SLM1(gene name synonym)|uniprotkb:Sam68-like mammalian protein 1(gene name synonym)|uniprotkb:KHDRBS2(gene name)|psi-mi:KHDRBS2(display_short)	psi-mi:mud2_yeast(display_long)|uniprotkb:MUD2(gene name)|psi-mi:MUD2(display_short)|uniprotkb:YKL358(orf name)|uniprotkb:YKL074C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11556796|imex:IM-24995-4554	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_689901.2|ensembl:ENSG00000112232(gene)|ensembl:ENST00000281156(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008143"("poly(A) binding")|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0017124"(SH3 domain binding)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR032335|interpro:IPR032571|interpro:IPR036612|reactome:R-HSA-8849468|entrezgene/locuslink:202559(identity)	go:"GO:0000243"(commitment complex)|go:"GO:0000348"(mRNA branch site recognition)|go:"GO:0003729"(mRNA binding)|go:"GO:0008187"(poly-pyrimidine tract binding)|go:"GO:0016607"(nuclear speck)|ensemblfungi:YKL074C(gene)|go:"GO:0030628"(pre-mRNA 3'-splice site binding)|go:"GO:0045131"(pre-mRNA branch point binding)|go:"GO:0071004"(U2-type prespliceosome)|ensemblfungi:YKL074C_mRNA(transcript)|go:"GO:0089701"(U2AF complex)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|refseq:NP_012849.1|sgd:S000001557|mint:P36084|dip:DIP-758N|sgd:YKL074C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:IfFvZO2dIAo0Sdx+BUb5c8F7aQY9606	rogid:l/aBULMxdezuufNxUE5qqnYEN1Y559292	intact-crc:4C757E8B4E6F87E1|rigid:dOhlVPfRR+6wCHG1eO4oovEzEsw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q15415	uniprotkb:P36084	intact:EBI-8642021|uniprotkb:B2R916|intact:MINT-8163253|ensembl:ENSP00000250831|ensembl:ENSP00000307155	intact:EBI-11612|ensemblfungi:YKL074C|uniprotkb:D6VXL2	psi-mi:rby1f_human(display_long)|uniprotkb:RBMY1F(gene name)|psi-mi:RBMY1F(display_short)|uniprotkb:RBMY1J(gene name)|psi-mi:RBMY1J(display_short)|uniprotkb:Y chromosome RNA recognition motif 2(gene name synonym)|uniprotkb:YRRM2(gene name synonym)	psi-mi:mud2_yeast(display_long)|uniprotkb:MUD2(gene name)|psi-mi:MUD2(display_short)|uniprotkb:YKL358(orf name)|uniprotkb:YKL074C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11556787|imex:IM-24995-4553	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001290339.1|refseq:NP_001006117.2|refseq:NP_689798.1|ensembl:ENSG00000169800(gene)|ensembl:ENSG00000226941(gene)|ensembl:ENST00000250831(transcript)|ensembl:ENST00000303766(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016607"(nuclear speck)|go:"GO:0042802"(identical protein binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012604(RBM1CTR)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|entrezgene/locuslink:159163(identity)	go:"GO:0000243"(commitment complex)|go:"GO:0000348"(mRNA branch site recognition)|go:"GO:0003729"(mRNA binding)|go:"GO:0008187"(poly-pyrimidine tract binding)|go:"GO:0016607"(nuclear speck)|ensemblfungi:YKL074C(gene)|go:"GO:0030628"(pre-mRNA 3'-splice site binding)|go:"GO:0045131"(pre-mRNA branch point binding)|go:"GO:0071004"(U2-type prespliceosome)|ensemblfungi:YKL074C_mRNA(transcript)|go:"GO:0089701"(U2AF complex)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|refseq:NP_012849.1|sgd:S000001557|mint:P36084|dip:DIP-758N|sgd:YKL074C(identity)	-	comment:mint	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:lEyv+LmtOFRifaC5g6jDlh5WCnM9606	rogid:l/aBULMxdezuufNxUE5qqnYEN1Y559292	intact-crc:B26A29896F4E3664|rigid:w65kkiCHGlmfPuALqJtb8HWbwCA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P36084	uniprotkb:O14641	intact:EBI-11612|ensemblfungi:YKL074C|uniprotkb:D6VXL2	intact:EBI-740850|ensembl:ENSP00000005340|uniprotkb:Q53XM0|uniprotkb:D3DTN3	psi-mi:mud2_yeast(display_long)|uniprotkb:MUD2(gene name)|psi-mi:MUD2(display_short)|uniprotkb:YKL358(orf name)|uniprotkb:YKL074C(locus name)	psi-mi:dvl2_human(display_long)|uniprotkb:DSH homolog 2(gene name synonym)|uniprotkb:DVL2(gene name)|psi-mi:DVL2(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11556778|imex:IM-24995-4552	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0000243"(commitment complex)|go:"GO:0000348"(mRNA branch site recognition)|go:"GO:0003729"(mRNA binding)|go:"GO:0008187"(poly-pyrimidine tract binding)|go:"GO:0016607"(nuclear speck)|ensemblfungi:YKL074C(gene)|go:"GO:0030628"(pre-mRNA 3'-splice site binding)|go:"GO:0045131"(pre-mRNA branch point binding)|go:"GO:0071004"(U2-type prespliceosome)|ensemblfungi:YKL074C_mRNA(transcript)|go:"GO:0089701"(U2AF complex)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|refseq:NP_012849.1|sgd:S000001557|mint:P36084|dip:DIP-758N|sgd:YKL074C(identity)	refseq:NP_004413.1|ensembl:ENSG00000004975(gene)|ensembl:ENST00000005340(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005109"(frizzled binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0007507"(heart development)|go:"GO:0016235"(aggresome)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044340"(canonical Wnt signaling pathway involved in regulation of cell proliferation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0150012"(positive regulation of neuron projection arborization)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008341(Dishevelled-2 region)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:O14641|rcsb pdb:2REY|rcsb pdb:3CBX|rcsb pdb:3CBY|rcsb pdb:3CBZ|rcsb pdb:3CC0|rcsb pdb:4WIP|rcsb pdb:5LNP|rcsb pdb:5SUY|rcsb pdb:5SUZ|rcsb pdb:6IW3|rcsb pdb:6JCK|reactome:R-HSA-201681|reactome:R-HSA-201688|reactome:R-HSA-2028269|reactome:R-HSA-4086400|reactome:R-HSA-4608870|reactome:R-HSA-4641258|reactome:R-HSA-4641262|reactome:R-HSA-5099900|reactome:R-HSA-5368598|reactome:R-HSA-5663220|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9673324|ensembl:ENSP00000005340|dip:DIP-34433N|entrezgene/locuslink:1856(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:l/aBULMxdezuufNxUE5qqnYEN1Y559292	rogid:2Vdc8oRnT4Mz/j+EXQXrL3AszOc9606	intact-crc:CCC8BF187E2F1C02|rigid:cAJUN1S7/U2jmncbEaTbGVNcAVk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O43765	uniprotkb:P38011	intact:EBI-347996|ensembl:ENSP00000221566|ensembl:ENSP00000503397|ensembl:ENSP00000504495|uniprotkb:Q9BTZ9|intact:EBI-1045243|uniprotkb:Q6FIA9|uniprotkb:D6W610	intact:EBI-7405|uniprotkb:Q6LAA5|uniprotkb:D6VZT9|ensemblfungi:YMR116C	psi-mi:sgta_human(display_long)|uniprotkb:SGTA(gene name)|psi-mi:SGTA(display_short)|uniprotkb:SGT(gene name synonym)|uniprotkb:Alpha-SGT(gene name synonym)|uniprotkb:Vpu-binding protein(gene name synonym)|uniprotkb:SGT1(gene name synonym)	psi-mi:gblp_yeast(display_long)|uniprotkb:ASC1(gene name)|psi-mi:ASC1(display_short)|uniprotkb:CPC2(gene name synonym)|uniprotkb:Receptor of activated protein kinase C 1(gene name synonym)|uniprotkb:Receptor for activated C kinase(gene name synonym)|uniprotkb:Small ribosomal subunit protein RACK1(gene name synonym)|uniprotkb:YM9718.15C(orf name)|uniprotkb:YMR116C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11556908|imex:IM-24995-4566	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:4CPG|rcsb pdb:4GOD|rcsb pdb:4GOE|rcsb pdb:4GOF|reactome:R-HSA-9609523|rcsb pdb:2VYI|ensembl:ENSG00000104969(gene)|ensembl:ENST00000221566(transcript)|ensembl:ENST00000676943(transcript)|ensembl:ENST00000677149(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072380"(TRC complex)|go:"GO:0098850"(extrinsic component of synaptic vesicle membrane)|go:"GO:1903070"(negative regulation of ER-associated ubiquitin-dependent protein catabolic process)|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)|go:"GO:1903646"(positive regulation of chaperone-mediated protein folding)|go:"GO:1904288"(BAT3 complex binding)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR032374|mint:O43765|refseq:XP_011526480.1|refseq:NP_003012.1|entrezgene/locuslink:6449(identity)	refseq:NP_013834.1|sgd:S000004722|mint:P38011|dip:DIP-6465N|ensemblfungi:YMR116C(gene)|ensemblfungi:YMR116C_mRNA(transcript)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001965"(G-protein alpha-subunit binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005092"(GDP-dissociation inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0008104"(protein localization)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0043022"(ribosome binding)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0072344"(rescue of stalled ribosome)|go:"GO:0080135"(regulation of cellular response to stress)|go:"GO:1902660"(negative regulation of glucose mediated signaling pathway)|go:"GO:2001125"(negative regulation of translational frameshifting)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|rcsb pdb:1TRJ|rcsb pdb:3FRX|rcsb pdb:3J6X|rcsb pdb:3J6Y|rcsb pdb:3J77|rcsb pdb:3J78|rcsb pdb:3RFG|rcsb pdb:3RFH|rcsb pdb:4U3M|rcsb pdb:4U3N|rcsb pdb:4U3U|rcsb pdb:4U4N|rcsb pdb:4U4O|rcsb pdb:4U4Q|rcsb pdb:4U4R|rcsb pdb:4U4U|rcsb pdb:4U4Y|rcsb pdb:4U4Z|rcsb pdb:4U50|rcsb pdb:4U51|rcsb pdb:4U52|rcsb pdb:4U53|rcsb pdb:4U55|rcsb pdb:4U56|rcsb pdb:4U6F|rcsb pdb:4V6I|rcsb pdb:4V7R|rcsb pdb:4V88|rcsb pdb:4V8Y|rcsb pdb:4V8Z|rcsb pdb:4V92|rcsb pdb:5DAT|rcsb pdb:5DC3|rcsb pdb:5DGE|rcsb pdb:5DGF|rcsb pdb:5DGV|rcsb pdb:5FCI|rcsb pdb:5FCJ|rcsb pdb:5I4L|rcsb pdb:5JUO|rcsb pdb:5JUP|rcsb pdb:5JUS|rcsb pdb:5JUT|rcsb pdb:5JUU|rcsb pdb:5LYB|rcsb pdb:5M1J|rcsb pdb:5MC6|rcsb pdb:5MEI|rcsb pdb:5NDG|rcsb pdb:5NDV|rcsb pdb:5NDW|rcsb pdb:5OBM|rcsb pdb:5ON6|rcsb pdb:5TBW|rcsb pdb:5TGA|rcsb pdb:5TGM|rcsb pdb:6FAI|rcsb pdb:6GQ1|rcsb pdb:6GQB|rcsb pdb:6GQV|rcsb pdb:6HHQ|rcsb pdb:6I7O|rcsb pdb:6Q8Y|rcsb pdb:6RBE|rcsb pdb:6S47|rcsb pdb:6SNT|rcsb pdb:6SV4|rcsb pdb:6T4Q|rcsb pdb:6T7I|rcsb pdb:6T7T|rcsb pdb:6T83|rcsb pdb:6TB3|rcsb pdb:6TNU|rcsb pdb:6WDR|rcsb pdb:6WOO|rcsb pdb:6XIQ|rcsb pdb:6XIR|rcsb pdb:6Z6J|rcsb pdb:6Z6K|rcsb pdb:6ZCE|rcsb pdb:6ZU9|rcsb pdb:6ZVI|rcsb pdb:7A1G|rcsb pdb:7NRC|rcsb pdb:7NRD|rcsb pdb:7B7D|sgd:YMR116C(identity)	-	-	crc64:B9A5D4959A3C54FB	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:r/Cyj4UJk/cS8QdrbjhTZMPCigI9606	rogid:T9ugPN58tGKmSOjRbv1bD1rznH8559292	intact-crc:8F3726601E132667|rigid:JI7BWoHcftxx3AMPzyO2ZAnVCjU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P37263	uniprotkb:Q9NP64	intact:EBI-21659|uniprotkb:D6VR87|ensemblfungi:YCR087C-A	intact:EBI-746345|uniprotkb:Q6PKH4|uniprotkb:Q9NYG4|uniprotkb:Q9P0M8|uniprotkb:D3DPN4|ensembl:ENSP00000343557|ensembl:ENSP00000362819|uniprotkb:B4DY38	psi-mi:yc16_yeast(display_long)|uniprotkb:YCRX16C(orf name)|uniprotkb:YCR087C-A(locus name)	psi-mi:no40_human(display_long)|uniprotkb:Zinc finger CCHC domain-containing protein 17(gene name synonym)|uniprotkb:Putative S1 RNA-binding domain protein(gene name synonym)|uniprotkb:Pnn-interacting nucleolar protein(gene name synonym)|uniprotkb:ZCCHC17(gene name)|psi-mi:ZCCHC17(display_short)|uniprotkb:HSPC243(orf name)|uniprotkb:HSPC251(orf name)|uniprotkb:LDC4(orf name)|uniprotkb:PS1D(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11556899|imex:IM-24995-4565	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010011.1|sgd:S000007223|mint:P37263|dip:DIP-4536N|ensemblfungi:YCR087C-A(gene)|ensemblfungi:YCR087C-A_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR014898(Zinc finger, C2H2, LYAR-type)|interpro:IPR036236|interpro:IPR039999|sgd:YCR087C-A(identity)	refseq:NP_001269495.1|refseq:NP_001269496.1|refseq:NP_001269497.1|refseq:NP_001269498.1|refseq:NP_001269499.1|refseq:NP_001269500.1|refseq:NP_001269501.1|refseq:NP_001269502.1|refseq:NP_001269503.1|refseq:XP_006710744.1|refseq:NP_057589.2|refseq:XP_011539869.1|ensembl:ENSG00000121766(gene)|ensembl:ENST00000344147(transcript)|ensembl:ENST00000373714(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0042802"(identical protein binding)|go:"GO:0043489"(RNA stabilization)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR003029(S1, RNA binding)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR022967|interpro:IPR037320|mint:Q9NP64|rcsb pdb:2CQO|entrezgene/locuslink:51538(identity)	-	crc64:B5B3B4CA37B82042	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:I7iIzRqPZAKdWQSe/IeGsW0qQcU559292	rogid:e71wAulRWX6cM59s3g8R42PWXeU9606	intact-crc:B7AC345AD5E11B41|rigid:Ml0Q/8mbm2fJgykAKfM9sgQUtFs	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P37263	uniprotkb:Q9HCM9-2	intact:EBI-21659|uniprotkb:D6VR87|ensemblfungi:YCR087C-A	intact:EBI-11523450|ensembl:ENSP00000365847|ensembl:ENSP00000373095|ensembl:ENSP00000373097|ensembl:ENSP00000379797|ensembl:ENSP00000379800|ensembl:ENSP00000383486|ensembl:ENSP00000387445|ensembl:ENSP00000389198|ensembl:ENSP00000389852|ensembl:ENSP00000392130|ensembl:ENSP00000394353|ensembl:ENSP00000396986|ensembl:ENSP00000398956|ensembl:ENSP00000401071|ensembl:ENSP00000401184|ensembl:ENSP00000404340|ensembl:ENSP00000404904|ensembl:ENSP00000411582|ensembl:ENSP00000412743|ensembl:ENSP00000414525|ensembl:ENSP00000415259	psi-mi:yc16_yeast(display_long)|uniprotkb:YCRX16C(orf name)|uniprotkb:YCR087C-A(locus name)	psi-mi:q9hcm9-2(display_long)|uniprotkb:TRIM39(gene name)|psi-mi:TRIM39(display_short)|uniprotkb:RING finger protein 23(gene name synonym)|uniprotkb:RNF23(gene name synonym)|uniprotkb:TFP(gene name synonym)|uniprotkb:Testis-abundant finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 39(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM39(gene name synonym)|uniprotkb:TIM39beta(isoform synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11556889|imex:IM-24995-4564	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010011.1|sgd:S000007223|mint:P37263|dip:DIP-4536N|ensemblfungi:YCR087C-A(gene)|ensemblfungi:YCR087C-A_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR014898(Zinc finger, C2H2, LYAR-type)|interpro:IPR036236|interpro:IPR039999|sgd:YCR087C-A(identity)	intact:EBI-739510(isoform-parent)|ensembl:ENSG00000204599(gene)|ensembl:ENSG00000206495(gene)|ensembl:ENSG00000224994(gene)|ensembl:ENSG00000226437(gene)|ensembl:ENSG00000229929(gene)|ensembl:ENSG00000230308(gene)|ensembl:ENSG00000232839(gene)|ensembl:ENST00000376659(transcript)|ensembl:ENST00000383601(transcript)|ensembl:ENST00000383603(transcript)|ensembl:ENST00000396548(transcript)|ensembl:ENST00000396551(transcript)|ensembl:ENST00000400644(transcript)|ensembl:ENST00000414015(transcript)|ensembl:ENST00000419790(transcript)|ensembl:ENST00000430502(transcript)|ensembl:ENST00000431272(transcript)|ensembl:ENST00000433900(transcript)|ensembl:ENST00000438076(transcript)|ensembl:ENST00000438859(transcript)|ensembl:ENST00000440117(transcript)|ensembl:ENST00000443109(transcript)|ensembl:ENST00000446397(transcript)|ensembl:ENST00000449318(transcript)|ensembl:ENST00000450778(transcript)|ensembl:ENST00000451132(transcript)|ensembl:ENST00000452705(transcript)|ensembl:ENST00000458607(transcript)|uniprotkb:Q9HCM9-2(isoform-parent)|entrezgene/locuslink:56658(identity)	-	crc64:B5B3B4CA37B82042	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:I7iIzRqPZAKdWQSe/IeGsW0qQcU559292	rogid:UfSn2+IVRxtGomVeDGdZpL7mz5I9606	intact-crc:8A3E54AD25339359|rigid:s7Y0G+75Dh7YfGv3z3b4iFW+XHA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P37263	uniprotkb:Q9H190	intact:EBI-21659|uniprotkb:D6VR87|ensemblfungi:YCR087C-A	intact:EBI-742426|ensembl:ENSP00000371233|uniprotkb:O95892|uniprotkb:Q5W0X1|uniprotkb:Q9BZ42|uniprotkb:Q9H567|uniprotkb:Q9NRY8|intact:EBI-28983470|ensembl:ENSP00000342935|ensembl:ENSP00000354013	psi-mi:yc16_yeast(display_long)|uniprotkb:YCRX16C(orf name)|uniprotkb:YCR087C-A(locus name)	psi-mi:sdcb2_human(display_long)|uniprotkb:Similar to TACIP18(gene name synonym)|uniprotkb:SDCBP2(gene name)|psi-mi:SDCBP2(display_short)|uniprotkb:SITAC18(gene name synonym)|uniprotkb:Syndecan-binding protein 2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11556880|imex:IM-24995-4563	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010011.1|sgd:S000007223|mint:P37263|dip:DIP-4536N|ensemblfungi:YCR087C-A(gene)|ensemblfungi:YCR087C-A_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR014898(Zinc finger, C2H2, LYAR-type)|interpro:IPR036236|interpro:IPR039999|sgd:YCR087C-A(identity)	refseq:NP_001186713.1|refseq:NP_056500.2|refseq:NP_536737.3|ensembl:ENSP00000342935|ensembl:ENSP00000354013|ensembl:ENST00000381808|ensembl:ENSP00000371229|ensembl:ENSP00000371233|ensembl:ENSG00000125775(gene)|ensembl:ENST00000360779(transcript)|ensembl:ENST00000381812(transcript)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007399"(nervous system development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016607"(nuclear speck)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046907"(intracellular transport)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036034|interpro:IPR041489|ensembl:ENST00000339987(transcript)|entrezgene/locuslink:27111(identity)	-	crc64:B5B3B4CA37B82042	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:I7iIzRqPZAKdWQSe/IeGsW0qQcU559292	rogid:vlEtVZkwLTte5PJ4i8ce+SwE/4Y9606	intact-crc:D6981A9DB7844422|rigid:GZKCUp0YggGGRChHC1eqHtSHdEc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q969J2	uniprotkb:P37263	intact:EBI-2818641|uniprotkb:B2RE32|uniprotkb:Q5U7L4|intact:EBI-28979011|ensembl:ENSP00000366509	intact:EBI-21659|uniprotkb:D6VR87|ensemblfungi:YCR087C-A	psi-mi:zksc4_human(display_long)|uniprotkb:ZKSCAN4(gene name)|psi-mi:ZKSCAN4(display_short)|uniprotkb:ZNF307(gene name synonym)|uniprotkb:ZNF427(gene name synonym)|uniprotkb:P373c6.1(gene name synonym)|uniprotkb:Zinc finger protein 307(gene name synonym)|uniprotkb:Zinc finger protein 427(gene name synonym)	psi-mi:yc16_yeast(display_long)|uniprotkb:YCRX16C(orf name)|uniprotkb:YCR087C-A(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11556871|imex:IM-24995-4562	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_061983.2|ensembl:ENSP00000366509|ensembl:ENSG00000187626(gene)|ensembl:ENST00000377294(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|interpro:IPR038269|mint:Q969J2|reactome:R-HSA-212436|refseq:XP_005249152.1|entrezgene/locuslink:387032(identity)	refseq:NP_010011.1|sgd:S000007223|mint:P37263|dip:DIP-4536N|ensemblfungi:YCR087C-A(gene)|ensemblfungi:YCR087C-A_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR014898(Zinc finger, C2H2, LYAR-type)|interpro:IPR036236|interpro:IPR039999|sgd:YCR087C-A(identity)	-	-	crc64:B5B3B4CA37B82042	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:5TWhAtzfmCXHkOSbjKwjgLIsCcs9606	rogid:I7iIzRqPZAKdWQSe/IeGsW0qQcU559292	intact-crc:A7AF0B2BD06526BD|rigid:sgHcAG6ilUhpQfZrKLC6ENwANsc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P37263	uniprotkb:P63279	intact:EBI-21659|uniprotkb:D6VR87|ensemblfungi:YCR087C-A	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	psi-mi:yc16_yeast(display_long)|uniprotkb:YCRX16C(orf name)|uniprotkb:YCR087C-A(locus name)	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11556862|imex:IM-24995-4561	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010011.1|sgd:S000007223|mint:P37263|dip:DIP-4536N|ensemblfungi:YCR087C-A(gene)|ensemblfungi:YCR087C-A_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR014898(Zinc finger, C2H2, LYAR-type)|interpro:IPR036236|interpro:IPR039999|sgd:YCR087C-A(identity)	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N|entrezgene/locuslink:7329(identity)	-	crc64:B5B3B4CA37B82042	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:I7iIzRqPZAKdWQSe/IeGsW0qQcU559292	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	intact-crc:3F269F6A206D0DCC|rigid:Qck8S7kbrP/Hrd/Os64j6Sm+l40	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q13422-7	uniprotkb:P36534	intact:EBI-11522367|ensembl:ENSP00000352123|ensembl:ENSP00000413025	intact:EBI-15595|uniprotkb:D6W3J5|uniprotkb:Q6B277|ensemblfungi:YPL173W	psi-mi:q13422-7(display_long)|uniprotkb:IKZF1(gene name)|psi-mi:IKZF1(display_short)|uniprotkb:IK1(gene name synonym)|uniprotkb:IKAROS(gene name synonym)|uniprotkb:Ikaros family zinc finger protein 1(gene name synonym)|uniprotkb:LYF1(gene name synonym)|uniprotkb:Lymphoid transcription factor LyF-1(gene name synonym)|uniprotkb:ZNFN1A1(gene name synonym)	psi-mi:rm40_yeast(display_long)|uniprotkb:YPL173W(locus name)|uniprotkb:MRPL40(gene name)|psi-mi:MRPL40(display_short)|uniprotkb:YmL40(gene name synonym)|uniprotkb:Mitochondrial large ribosomal subunit protein uL24m(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11556853|imex:IM-24995-4560	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-745305(isoform-parent)|ensembl:ENSG00000185811(gene)|ensembl:ENST00000359197(transcript)|ensembl:ENST00000439701(transcript)|uniprotkb:Q13422-7(isoform-parent)|entrezgene/locuslink:10320(identity)	refseq:NP_015152.1|sgd:S000006094|ensemblfungi:YPL173W(gene)|ensemblfungi:YPL173W_mRNA(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0006412"(translation)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR003256(Ribosomal protein L24)|interpro:IPR005824(KOW)|interpro:IPR005825(Ribosomal protein L24/L26, conserved site)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR014722(Translation protein SH3-like, subgroup)|rcsb pdb:3J6B|rcsb pdb:5MRC|rcsb pdb:5MRE|rcsb pdb:5MRF|dip:DIP-7947N|mint:P36534|sgd:YPL173W(identity)	-	-	crc64:D5BB2B7AE13ECBF9	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:ou/ovXYoMneBNVp4pj38VxenfyY9606	rogid:NDbI5dslWtZzVGLPfKQTxT2o/bc559292	intact-crc:9881B7FE32DECF7A|rigid:P3hHvaBL/xXDnJCNMpzj6COuUyc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P36149	uniprotkb:Q08379	intact:EBI-3567|uniprotkb:D6VXC9|ensemblfungi:YKR068C	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	psi-mi:bet3_yeast(display_long)|uniprotkb:YKR068C(locus name)|uniprotkb:BET3(gene name)|psi-mi:BET3(display_short)|uniprotkb:Transport protein particle 22 kDa subunit(gene name synonym)	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11556842|imex:IM-24995-4559	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012994.1|sgd:S000001776|dip:DIP-1710N|mint:P36149|ensemblfungi:YKR068C(gene)|ensemblfungi:YKR068C_mRNA(transcript)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0030008"(TRAPP complex)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0033106"(cis-Golgi network membrane)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:1990070"(TRAPPI protein complex)|go:"GO:1990071"(TRAPPII protein complex)|go:"GO:1990072"(TRAPPIII protein complex)|interpro:IPR007194("Transport protein particle (TRAPP) component, Bet3")|interpro:IPR016721(TRAPP I complex, Bet3)|interpro:IPR024096|rcsb pdb:3CUE|rcsb pdb:7KMT|reactome:R-SCE-204005|reactome:R-SCE-8876198|sgd:YKR068C(identity)	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N|entrezgene/locuslink:2801(identity)	-	crc64:C802D8A3563DE82B	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2017/05/26	rogid:XN0vyDhpSkOFxu+sgthTqABoSxM559292	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	intact-crc:65C200D26020BBD5|rigid:pgPBy01O66tFxjGKHTFMly7kMfQ	false	-	sufficient binding region:383-1002	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q08379	uniprotkb:P38128	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	intact:EBI-17469|uniprotkb:D6VQH6|ensemblfungi:YBR182C	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:smp1_yeast(display_long)|uniprotkb:YBR1245(orf name)|uniprotkb:YBR182C(locus name)|uniprotkb:SMP1(gene name)|psi-mi:SMP1(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11556944|imex:IM-24995-4570	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N|entrezgene/locuslink:2801(identity)	refseq:NP_009741.3|sgd:S000000386|interpro:IPR002100(Transcription factor, MADS-box)|ensemblfungi:YBR182C(gene)|ensemblfungi:YBR182C_mRNA(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|reactome:R-SCE-525793|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR033896|interpro:IPR036879|sgd:YBR182C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2017/05/26	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	rogid:+iBP5NzZkrXnslYfo1RDMrlTAIQ559292	intact-crc:036D6F5322B5AE7C|rigid:PmM+1BLaqJRaEfEEELirz9uDHbg	false	sufficient binding region:383-1002	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q14145	uniprotkb:P38109	intact:EBI-751001|uniprotkb:B3KPD5|uniprotkb:Q8WTX1|uniprotkb:Q6LEP0|uniprotkb:Q9BPY9|intact:EBI-28976014|ensembl:ENSP00000171111|ensembl:ENSP00000377245	intact:EBI-21638|uniprotkb:D6VQD5|ensemblfungi:YBR139W	psi-mi:keap1_human(display_long)|uniprotkb:Cytosolic inhibitor of Nrf2(gene name synonym)|uniprotkb:Kelch-like protein 19(gene name synonym)|uniprotkb:KEAP1(gene name)|psi-mi:KEAP1(display_short)|uniprotkb:INRF2(gene name synonym)|uniprotkb:KIAA0132(gene name synonym)|uniprotkb:KLHL19(gene name synonym)	psi-mi:yby9_yeast(display_long)|uniprotkb:YBR1015(orf name)|uniprotkb:YBR139W(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11556935|imex:IM-24995-4569	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_036421.2|refseq:NP_987096.1|ensembl:ENSP00000171111|ensembl:ENSP00000377245|refseq:XP_011526754.1|refseq:XP_005260230.1|refseq:XP_005260231.1|dip:DIP-42134N|ensembl:ENSG00000079999(gene)|ensembl:ENST00000171111(transcript)|ensembl:ENST00000393623(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0016234"(inclusion body)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030496"(midbody)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0034451"(centriolar satellite)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045604"(regulation of epidermal cell differentiation)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR017096(Kelch-like protein, gigaxonin)|interpro:IPR030563|mint:Q14145|rcsb pdb:1U6D|rcsb pdb:1ZGK|rcsb pdb:2FLU|rcsb pdb:3VNG|rcsb pdb:3VNH|rcsb pdb:3ZGC|rcsb pdb:3ZGD|rcsb pdb:4CXI|rcsb pdb:4CXJ|rcsb pdb:4CXT|rcsb pdb:4IFJ|rcsb pdb:4IFL|rcsb pdb:4IFN|rcsb pdb:4IN4|rcsb pdb:4IQK|rcsb pdb:4L7B|rcsb pdb:4L7C|rcsb pdb:4L7D|rcsb pdb:4N1B|rcsb pdb:4XMB|rcsb pdb:5DAD|rcsb pdb:5DAF|rcsb pdb:5F72|rcsb pdb:5GIT|rcsb pdb:5NLB|rcsb pdb:5WFL|rcsb pdb:5WFV|rcsb pdb:5WG1|rcsb pdb:5WHL|rcsb pdb:5WHO|rcsb pdb:5WIY|rcsb pdb:5X54|rcsb pdb:6FFM|rcsb pdb:6FMP|rcsb pdb:6FMQ|rcsb pdb:6HWS|rcsb pdb:6LRZ|rcsb pdb:6ROG|rcsb pdb:6SP1|rcsb pdb:6SP4|rcsb pdb:6T7V|rcsb pdb:6T7Z|rcsb pdb:6TG8|rcsb pdb:6TYM|rcsb pdb:6TYP|rcsb pdb:6UF0|rcsb pdb:6W66|rcsb pdb:6W67|rcsb pdb:6W68|rcsb pdb:6W69|rcsb pdb:6WCQ|rcsb pdb:6Z6A|rcsb pdb:7K28|rcsb pdb:7K29|rcsb pdb:7K2A|rcsb pdb:7K2B|rcsb pdb:7K2C|rcsb pdb:7K2D|rcsb pdb:7K2E|rcsb pdb:7K2F|rcsb pdb:7K2G|rcsb pdb:7K2H|rcsb pdb:7K2I|rcsb pdb:7K2J|rcsb pdb:7K2K|rcsb pdb:7K2L|rcsb pdb:7K2M|rcsb pdb:7K2N|rcsb pdb:7K2O|rcsb pdb:7K2P|rcsb pdb:7K2Q|rcsb pdb:7K2R|rcsb pdb:7K2S|reactome:R-HSA-5689880|reactome:R-HSA-8932339|reactome:R-HSA-8951664|reactome:R-HSA-983168|rcsb pdb:6V6Z|entrezgene/locuslink:9817(identity)	sgd:S000000343|refseq:NP_009697.3|mint:P38109|dip:DIP-4923N|ensemblfungi:YBR139W(gene)|ensemblfungi:YBR139W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000328"(fungal-type vacuole lumen)|go:"GO:0004185"(serine-type carboxypeptidase activity)|go:"GO:0016236"(macroautophagy)|go:"GO:0017171"(serine hydrolase activity)|go:"GO:0031638"(zymogen activation)|go:"GO:0046938"(phytochelatin biosynthetic process)|interpro:IPR001563(Peptidase S10, serine carboxypeptidase)|interpro:IPR018202|interpro:IPR029058|interpro:IPR033124|sgd:YBR139W(identity)	-	-	crc64:AAB2806C8EE2EDE1	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:3y/KqnUK+5nIyjhOEfkkthmP1OA9606	rogid:x1bs6aRSmYGGBe4qebG37+9v4ek559292	intact-crc:52326A3BF0E43FBE|rigid:H05m15ogeIMWg5dFsLakXE30J8g	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38084	uniprotkb:Q8N6L0	intact:EBI-3414|uniprotkb:D6VQ67|ensemblfungi:YBR068C	intact:EBI-749265|uniprotkb:Q96MC3|ensembl:ENSP00000404220	psi-mi:bap2_yeast(display_long)|uniprotkb:Branched-chain amino-acid permease 2(gene name synonym)|uniprotkb:BAP2(gene name)|psi-mi:BAP2(display_short)|uniprotkb:YBR068C(locus name)|uniprotkb:YBR0629(orf name)	psi-mi:kash5_human(display_long)|uniprotkb:KASH5(gene name)|psi-mi:KASH5(display_short)|uniprotkb:CCDC155(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 155(gene name synonym)|uniprotkb:KASH domain-containing protein 5(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11556926|imex:IM-24995-4568	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000000272|refseq:NP_009624.4|dip:DIP-4910N|mint:P38084|ensemblfungi:YBR068C(gene)|ensemblfungi:YBR068C_mRNA(transcript)|go:"GO:0003333"(amino acid transmembrane transport)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006865"(amino acid transport)|go:"GO:0015171"(amino acid transmembrane transporter activity)|go:"GO:0015192"(L-phenylalanine transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0055085"(transmembrane transport)|go:"GO:0098713"(leucine import across plasma membrane)|interpro:IPR004762(Amino acid permease, fungi)|interpro:IPR004840(Amino acid permease, conserved site)|interpro:IPR004841(Amino acid permease-associated region)|sgd:YBR068C(identity)	refseq:NP_653289.3|ensembl:ENSG00000161609(gene)|ensembl:ENST00000447857(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034397"(telomere localization)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051225"(spindle assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0090172"(microtubule cytoskeleton organization involved in homologous chromosome segregation)|go:"GO:0090220"(chromosome localization to nuclear envelope involved in homologous chromosome segregation)|go:"GO:0090619"(meiotic spindle pole)|interpro:IPR011992(EF-Hand type)|interpro:IPR028168|interpro:IPR028170|interpro:IPR039508|mint:Q8N6L0|rcsb pdb:6R2I|rcsb pdb:6WMF|entrezgene/locuslink:147872(identity)	-	crc64:B87FD6A7464E07F5	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:7Fw7+M5mBikZBztHE2tSDpvBi/M559292	rogid:Wl9L7AcvDHCZuKjYLn8QgGIbZTc9606	intact-crc:3E78053958CF4D39|rigid:06KZtVfu+Zg0jAEL0cOjOPGPNAI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38011	uniprotkb:Q13829	intact:EBI-7405|uniprotkb:Q6LAA5|uniprotkb:D6VZT9|ensemblfungi:YMR116C	intact:EBI-2505861|uniprotkb:B7Z6M4|uniprotkb:Q5TZQ1|ensembl:ENSP00000226225	psi-mi:gblp_yeast(display_long)|uniprotkb:ASC1(gene name)|psi-mi:ASC1(display_short)|uniprotkb:CPC2(gene name synonym)|uniprotkb:Receptor of activated protein kinase C 1(gene name synonym)|uniprotkb:Receptor for activated C kinase(gene name synonym)|uniprotkb:Small ribosomal subunit protein RACK1(gene name synonym)|uniprotkb:YM9718.15C(orf name)|uniprotkb:YMR116C(locus name)	psi-mi:bacd2_human(display_long)|uniprotkb:BACURD2(gene name synonym)|uniprotkb:BTB/POZ domain-containing protein TNFAIP1(gene name synonym)|uniprotkb:Protein B12(gene name synonym)|uniprotkb:TNFAIP1(gene name)|psi-mi:TNFAIP1(display_short)|uniprotkb:EDP1(gene name synonym)|uniprotkb:Tumor necrosis factor, alpha-induced protein 1, endothelial(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11556917|imex:IM-24995-4567	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013834.1|sgd:S000004722|mint:P38011|dip:DIP-6465N|ensemblfungi:YMR116C(gene)|ensemblfungi:YMR116C_mRNA(transcript)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001965"(G-protein alpha-subunit binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005092"(GDP-dissociation inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0008104"(protein localization)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0043022"(ribosome binding)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0072344"(rescue of stalled ribosome)|go:"GO:0080135"(regulation of cellular response to stress)|go:"GO:1902660"(negative regulation of glucose mediated signaling pathway)|go:"GO:2001125"(negative regulation of translational frameshifting)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|rcsb pdb:1TRJ|rcsb pdb:3FRX|rcsb pdb:3J6X|rcsb pdb:3J6Y|rcsb pdb:3J77|rcsb pdb:3J78|rcsb pdb:3RFG|rcsb pdb:3RFH|rcsb pdb:4U3M|rcsb pdb:4U3N|rcsb pdb:4U3U|rcsb pdb:4U4N|rcsb pdb:4U4O|rcsb pdb:4U4Q|rcsb pdb:4U4R|rcsb pdb:4U4U|rcsb pdb:4U4Y|rcsb pdb:4U4Z|rcsb pdb:4U50|rcsb pdb:4U51|rcsb pdb:4U52|rcsb pdb:4U53|rcsb pdb:4U55|rcsb pdb:4U56|rcsb pdb:4U6F|rcsb pdb:4V6I|rcsb pdb:4V7R|rcsb pdb:4V88|rcsb pdb:4V8Y|rcsb pdb:4V8Z|rcsb pdb:4V92|rcsb pdb:5DAT|rcsb pdb:5DC3|rcsb pdb:5DGE|rcsb pdb:5DGF|rcsb pdb:5DGV|rcsb pdb:5FCI|rcsb pdb:5FCJ|rcsb pdb:5I4L|rcsb pdb:5JUO|rcsb pdb:5JUP|rcsb pdb:5JUS|rcsb pdb:5JUT|rcsb pdb:5JUU|rcsb pdb:5LYB|rcsb pdb:5M1J|rcsb pdb:5MC6|rcsb pdb:5MEI|rcsb pdb:5NDG|rcsb pdb:5NDV|rcsb pdb:5NDW|rcsb pdb:5OBM|rcsb pdb:5ON6|rcsb pdb:5TBW|rcsb pdb:5TGA|rcsb pdb:5TGM|rcsb pdb:6FAI|rcsb pdb:6GQ1|rcsb pdb:6GQB|rcsb pdb:6GQV|rcsb pdb:6HHQ|rcsb pdb:6I7O|rcsb pdb:6Q8Y|rcsb pdb:6RBE|rcsb pdb:6S47|rcsb pdb:6SNT|rcsb pdb:6SV4|rcsb pdb:6T4Q|rcsb pdb:6T7I|rcsb pdb:6T7T|rcsb pdb:6T83|rcsb pdb:6TB3|rcsb pdb:6TNU|rcsb pdb:6WDR|rcsb pdb:6WOO|rcsb pdb:6XIQ|rcsb pdb:6XIR|rcsb pdb:6Z6J|rcsb pdb:6Z6K|rcsb pdb:6ZCE|rcsb pdb:6ZU9|rcsb pdb:6ZVI|rcsb pdb:7A1G|rcsb pdb:7NRC|rcsb pdb:7NRD|rcsb pdb:7B7D|sgd:YMR116C(identity)	refseq:NP_066960.1|ensembl:ENSG00000109079(gene)|ensembl:ENST00000226225(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006955"(immune response)|go:"GO:0016477"(cell migration)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030332"(cyclin binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0043149"(stress fiber assembly)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0051260"(protein homooligomerization)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR003131(Potassium channel, voltage dependent, Kv,  tetramerisation)|interpro:IPR011333(BTB/POZ fold)|mint:Q13829|reactome:R-HSA-9696264|reactome:R-HSA-9696270|entrezgene/locuslink:7126(identity)	-	crc64:B9A5D4959A3C54FB	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:T9ugPN58tGKmSOjRbv1bD1rznH8559292	rogid:8vM9HnNmkirDbJRETV/TeE8pONY9606	intact-crc:0C63351D984681C2|rigid:JG78HbwXtpeoM+ZQxJKJuB72en0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38128	uniprotkb:O14641	intact:EBI-17469|uniprotkb:D6VQH6|ensemblfungi:YBR182C	intact:EBI-740850|ensembl:ENSP00000005340|uniprotkb:Q53XM0|uniprotkb:D3DTN3	psi-mi:smp1_yeast(display_long)|uniprotkb:YBR1245(orf name)|uniprotkb:YBR182C(locus name)|uniprotkb:SMP1(gene name)|psi-mi:SMP1(display_short)	psi-mi:dvl2_human(display_long)|uniprotkb:DSH homolog 2(gene name synonym)|uniprotkb:DVL2(gene name)|psi-mi:DVL2(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11556964|imex:IM-24995-4572	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009741.3|sgd:S000000386|interpro:IPR002100(Transcription factor, MADS-box)|ensemblfungi:YBR182C(gene)|ensemblfungi:YBR182C_mRNA(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|reactome:R-SCE-525793|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR033896|interpro:IPR036879|sgd:YBR182C(identity)	refseq:NP_004413.1|ensembl:ENSG00000004975(gene)|ensembl:ENST00000005340(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005109"(frizzled binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0007507"(heart development)|go:"GO:0016235"(aggresome)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044340"(canonical Wnt signaling pathway involved in regulation of cell proliferation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0150012"(positive regulation of neuron projection arborization)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008341(Dishevelled-2 region)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:O14641|rcsb pdb:2REY|rcsb pdb:3CBX|rcsb pdb:3CBY|rcsb pdb:3CBZ|rcsb pdb:3CC0|rcsb pdb:4WIP|rcsb pdb:5LNP|rcsb pdb:5SUY|rcsb pdb:5SUZ|rcsb pdb:6IW3|rcsb pdb:6JCK|reactome:R-HSA-201681|reactome:R-HSA-201688|reactome:R-HSA-2028269|reactome:R-HSA-4086400|reactome:R-HSA-4608870|reactome:R-HSA-4641258|reactome:R-HSA-4641262|reactome:R-HSA-5099900|reactome:R-HSA-5368598|reactome:R-HSA-5663220|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9673324|ensembl:ENSP00000005340|dip:DIP-34433N|entrezgene/locuslink:1856(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:+iBP5NzZkrXnslYfo1RDMrlTAIQ559292	rogid:2Vdc8oRnT4Mz/j+EXQXrL3AszOc9606	intact-crc:83E22808FA821361|rigid:S5InodNAye0yjRMkLGG5XROWwz0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O00505	uniprotkb:P38128	intact:EBI-358297|intact:EBI-28976892|ensembl:ENSP00000261667|uniprotkb:O00191|uniprotkb:O43195|uniprotkb:Q96AA7|uniprotkb:Q5JVM9|intact:EBI-742146|uniprotkb:Q8IYQ9	intact:EBI-17469|uniprotkb:D6VQH6|ensemblfungi:YBR182C	psi-mi:ima4_human(display_long)|uniprotkb:KPNA3(gene name)|psi-mi:KPNA3(display_short)|uniprotkb:QIP2(gene name synonym)|uniprotkb:Karyopherin subunit alpha-3(gene name synonym)|uniprotkb:SRP1-gamma(gene name synonym)|uniprotkb:Importin alpha Q2(gene name synonym)	psi-mi:smp1_yeast(display_long)|uniprotkb:YBR1245(orf name)|uniprotkb:YBR182C(locus name)|uniprotkb:SMP1(gene name)|psi-mi:SMP1(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11556955|imex:IM-24995-4571	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000102753(gene)|ensembl:ENST00000261667(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0043657"(host cell)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0075732"(viral penetration into host nucleus)|interpro:IPR000225(Armadillo)|refseq:NP_002258.2|ensembl:ENSP00000261667|dip:DIP-27586N|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|mint:O00505|reactome:R-HSA-1169408|reactome:R-HSA-168276|entrezgene/locuslink:3839(identity)	refseq:NP_009741.3|sgd:S000000386|interpro:IPR002100(Transcription factor, MADS-box)|ensemblfungi:YBR182C(gene)|ensemblfungi:YBR182C_mRNA(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|reactome:R-SCE-525793|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR033896|interpro:IPR036879|sgd:YBR182C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:kx/oTYWMYG7dhwJHvr1POLD6FTU9606	rogid:+iBP5NzZkrXnslYfo1RDMrlTAIQ559292	intact-crc:58F3AFCF68DF74D9|rigid:vW49bMlKUJPjsYRy+VockKtA2Hg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8N7W2-2	uniprotkb:P38151	intact:EBI-10181188|ensembl:ENSP00000367868	intact:EBI-12968|uniprotkb:D6VQM8|ensemblfungi:YBR233W	psi-mi:q8n7w2-2(display_long)|uniprotkb:C10orf30(gene name synonym)|uniprotkb:BEND7(gene name)|psi-mi:BEND7(display_short)	psi-mi:pbp2_yeast(display_long)|uniprotkb:YBR1531(orf name)|uniprotkb:YBR233W(locus name)|uniprotkb:PBP2(gene name)|psi-mi:PBP2(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11557029|imex:IM-24995-4579	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000165626(gene)|ensembl:ENST00000378605(transcript)|intact:EBI-743382(isoform-parent)|uniprotkb:Q8N7W2-2(isoform-parent)|entrezgene/locuslink:222389(identity)	sgd:S000000437|refseq:NP_009792.3|dip:DIP-4947N|ensemblfungi:YBR233W(gene)|ensemblfungi:YBR233W_mRNA(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0051252"(regulation of RNA metabolic process)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR036612|sgd:YBR233W(identity)	-	-	crc64:638846509BCE1840	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:p6qrTn80hLyVU0W2Tvwn50Q4m5I9606	rogid:zcN9K+pivnit4l3Cl75wfk5F4VI559292	intact-crc:07C95CA10DFE82B4|rigid:mnpGnz+q9xWMm9vKv1ViKcntT3M	false	sufficient binding region:10-374	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P09012	uniprotkb:P38151	intact:EBI-607085|ensembl:ENSP00000243563	intact:EBI-12968|uniprotkb:D6VQM8|ensemblfungi:YBR233W	psi-mi:snrpa_human(display_long)|uniprotkb:SNRPA(gene name)|psi-mi:SNRPA(display_short)	psi-mi:pbp2_yeast(display_long)|uniprotkb:YBR1531(orf name)|uniprotkb:YBR233W(locus name)|uniprotkb:PBP2(gene name)|psi-mi:PBP2(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11557020|imex:IM-24995-4578	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005685"(U1 snRNP)|go:"GO:0030619"(U1 snRNA binding)|ensembl:ENSG00000077312(gene)|go:"GO:0042802"(identical protein binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034407|interpro:IPR034409|interpro:IPR035979|mint:P09012|rcsb pdb:1AUD|ensembl:ENST00000243563(transcript)|rcsb pdb:1DRZ|rcsb pdb:1DZ5|rcsb pdb:1FHT|rcsb pdb:1M5K|rcsb pdb:1M5O|rcsb pdb:1M5P|rcsb pdb:1M5V|rcsb pdb:1NU4|rcsb pdb:1OIA|rcsb pdb:1SJ3|rcsb pdb:1SJ4|rcsb pdb:1SJF|rcsb pdb:1U6B|rcsb pdb:1URN|rcsb pdb:1VBX|rcsb pdb:1VBY|rcsb pdb:1VBZ|rcsb pdb:1VC0|rcsb pdb:1VC5|rcsb pdb:1VC6|rcsb pdb:1ZZN|rcsb pdb:2A3J|rcsb pdb:2NZ4|rcsb pdb:2OIH|rcsb pdb:2OJ3|rcsb pdb:2U1A|rcsb pdb:3BO2|rcsb pdb:3BO3|rcsb pdb:3BO4|rcsb pdb:3CUL|rcsb pdb:3CUN|rcsb pdb:3EGZ|rcsb pdb:3G8S|rcsb pdb:3G8T|rcsb pdb:3G96|rcsb pdb:3G9C|rcsb pdb:3HHN|rcsb pdb:3IIN|rcsb pdb:3IRW|rcsb pdb:3IWN|rcsb pdb:3K0J|rcsb pdb:3L3C|rcsb pdb:3MUM|rcsb pdb:3MUR|rcsb pdb:3MUT|rcsb pdb:3R1H|rcsb pdb:3R1L|rcsb pdb:3UCU|rcsb pdb:3UCZ|rcsb pdb:3UD3|rcsb pdb:3UD4|rcsb pdb:3MUV|rcsb pdb:3UTR|rcsb pdb:4C4W|rcsb pdb:4PR6|rcsb pdb:4PRF|rcsb pdb:4W90|rcsb pdb:4W92|rcsb pdb:3MXH|rcsb pdb:3P49|rcsb pdb:3PGW|rcsb pdb:4YB1|rcsb pdb:5DDO|rcsb pdb:5DDP|rcsb pdb:5DDQ|rcsb pdb:5DDR|rcsb pdb:5FJ4|rcsb pdb:6LAS|rcsb pdb:6LAU|rcsb pdb:6LAX|rcsb pdb:6LAZ|rcsb pdb:6QX9|rcsb pdb:6SQN|rcsb pdb:6SQQ|rcsb pdb:6SQT|rcsb pdb:6SQV|rcsb pdb:6SR7|rcsb pdb:6XH0|rcsb pdb:6XH1|rcsb pdb:6XH2|rcsb pdb:6XH3|rcsb pdb:7AEP|rcsb pdb:7B0Y|rcsb pdb:7D7V|rcsb pdb:7LHX|reactome:R-HSA-72163|refseq:NP_004587.1|dip:DIP-29407N|entrezgene/locuslink:6626(identity)	sgd:S000000437|refseq:NP_009792.3|dip:DIP-4947N|ensemblfungi:YBR233W(gene)|ensemblfungi:YBR233W_mRNA(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0051252"(regulation of RNA metabolic process)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR036612|sgd:YBR233W(identity)	-	-	crc64:638846509BCE1840	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:BJ9zdDzOPs9JYgU8lErj/maq0AY9606	rogid:zcN9K+pivnit4l3Cl75wfk5F4VI559292	intact-crc:64C670C835FE24E6|rigid:VvCgiZmrrXTe79IE0dPM+8vL6Iw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q08379	uniprotkb:P38151	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	intact:EBI-12968|uniprotkb:D6VQM8|ensemblfungi:YBR233W	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:pbp2_yeast(display_long)|uniprotkb:YBR1531(orf name)|uniprotkb:YBR233W(locus name)|uniprotkb:PBP2(gene name)|psi-mi:PBP2(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11557009|imex:IM-24995-4577	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N|entrezgene/locuslink:2801(identity)	sgd:S000000437|refseq:NP_009792.3|dip:DIP-4947N|ensemblfungi:YBR233W(gene)|ensemblfungi:YBR233W_mRNA(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0051252"(regulation of RNA metabolic process)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR036612|sgd:YBR233W(identity)	-	-	crc64:638846509BCE1840	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2017/05/26	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	rogid:zcN9K+pivnit4l3Cl75wfk5F4VI559292	intact-crc:25ADDA87054CD5BE|rigid:xQUBfMMwoTlpWhUucmKFmlQ9oAA	false	sufficient binding region:383-1002	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96ED9-2	uniprotkb:P38148	intact:EBI-10961706|ensembl:ENSP00000264827	intact:EBI-21161|uniprotkb:D6VQS2|ensemblfungi:YBR276C	psi-mi:q96ed9-2(display_long)|uniprotkb:HOOK2(gene name)|psi-mi:HOOK2(display_short)	psi-mi:pps1_yeast(display_long)|uniprotkb:YBR2013(orf name)|uniprotkb:YBR276C(locus name)|uniprotkb:PPS1(gene name)|psi-mi:PPS1(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11557000|imex:IM-24995-4576	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000095066(gene)|ensembl:ENST00000264827(transcript)|intact:EBI-743290(isoform-parent)|uniprotkb:Q96ED9-2(isoform-parent)|entrezgene/locuslink:29911(identity)	refseq:NP_009835.3|sgd:S000000480|mint:P38148|dip:DIP-6546N|ensemblfungi:YBR276C(gene)|ensemblfungi:YBR276C_mRNA(transcript)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0008138"(protein tyrosine/serine/threonine phosphatase activity)|go:"GO:0033260"(nuclear DNA replication)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR000340(Protein-tyrosine phosphatase, dual specificity)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR020422|interpro:IPR029021|sgd:YBR276C(identity)	-	-	crc64:17840CF7256EF785	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:aJZ/iDJpRk5dFL1NiouLuTjnOnc9606	rogid:wB3u8/rxsyTrBOJKCyqomBBHGyE559292	intact-crc:EDCEF4665726FF3E|rigid:G1FQB0O5hccyrpSsh+7wLum1r9I	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38128	uniprotkb:Q9NRQ2	intact:EBI-17469|uniprotkb:D6VQH6|ensemblfungi:YBR182C	intact:EBI-769257|uniprotkb:Q2TTR3|uniprotkb:Q658L3|uniprotkb:Q7Z505|uniprotkb:A8K2E9|uniprotkb:Q6ZR73|ensembl:ENSP00000347038|ensembl:ENSP00000399315|ensembl:ENSP00000419040	psi-mi:smp1_yeast(display_long)|uniprotkb:YBR1245(orf name)|uniprotkb:YBR182C(locus name)|uniprotkb:SMP1(gene name)|psi-mi:SMP1(display_short)	psi-mi:pls4_human(display_long)|uniprotkb:"Ca(2+)-dependent phospholipid scramblase 4"(gene name synonym)|uniprotkb:TRA1(gene name synonym)|uniprotkb:Cell growth-inhibiting gene 43 protein(gene name synonym)|uniprotkb:PLSCR4(gene name)|psi-mi:PLSCR4(display_short)|uniprotkb:GIG43(orf name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11556991|imex:IM-24995-4575	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009741.3|sgd:S000000386|interpro:IPR002100(Transcription factor, MADS-box)|ensemblfungi:YBR182C(gene)|ensemblfungi:YBR182C_mRNA(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|reactome:R-SCE-525793|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR033896|interpro:IPR036879|sgd:YBR182C(identity)	refseq:XP_005247711.1|refseq:XP_005247712.1|refseq:NP_001121778.1|refseq:NP_001170775.1|refseq:NP_065086.2|refseq:NP_001121776.1|refseq:NP_001121777.1|refseq:XP_011511333.1|ensembl:ENSP00000347038|ensembl:ENST00000433593|ensembl:ENSP00000415605|ensembl:ENSP00000399315|ensembl:ENSP00000419040|ensembl:ENSG00000114698(gene)|ensembl:ENST00000354952(transcript)|ensembl:ENST00000446574(transcript)|ensembl:ENST00000493382(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017121"(plasma membrane phospholipid scrambling)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0017128"(phospholipid scramblase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0071222"(cellular response to lipopolysaccharide)|interpro:IPR005552(Scramblase)|rcsb pdb:3Q5U|entrezgene/locuslink:57088(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:+iBP5NzZkrXnslYfo1RDMrlTAIQ559292	rogid:bqEhBoGZZebMZn4JWpg/X0qU49A9606	intact-crc:CAC2FF3953C74BDA|rigid:dnwTh4HBKpMmYhau8jiYq073Chc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38128	uniprotkb:P62714	intact:EBI-17469|uniprotkb:D6VQH6|ensemblfungi:YBR182C	intact:EBI-1044367|ensembl:ENSP00000221138|uniprotkb:P11082|uniprotkb:D3DSV4|uniprotkb:Q6FHK5	psi-mi:smp1_yeast(display_long)|uniprotkb:YBR1245(orf name)|uniprotkb:YBR182C(locus name)|uniprotkb:SMP1(gene name)|psi-mi:SMP1(display_short)	psi-mi:pp2ab_human(display_long)|uniprotkb:PPP2CB(gene name)|psi-mi:PPP2CB(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11556982|imex:IM-24995-4574	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009741.3|sgd:S000000386|interpro:IPR002100(Transcription factor, MADS-box)|ensemblfungi:YBR182C(gene)|ensemblfungi:YBR182C_mRNA(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|reactome:R-SCE-525793|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR033896|interpro:IPR036879|sgd:YBR182C(identity)	refseq:NP_001009552.1|ensembl:ENSG00000104695(gene)|ensembl:ENST00000221138(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0010288"(response to lead ion)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046872"(metal ion binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|go:"GO:0006470"(protein dephosphorylation)|interpro:IPR029052|mint:P62714|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5675221|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-6804757|reactome:R-HSA-5673000|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|dip:DIP-42325N|entrezgene/locuslink:5516(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:+iBP5NzZkrXnslYfo1RDMrlTAIQ559292	rogid:ZWmB6it7rr0BS5sy38IxZ9QdR7U9606	intact-crc:72A4F8F1819E6420|rigid:XK/kpDX0uyVVJjPhxen/wCS2Yyc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38128	uniprotkb:P14373	intact:EBI-17469|uniprotkb:D6VQH6|ensemblfungi:YBR182C	intact:EBI-719493|uniprotkb:A2BE15|uniprotkb:Q5RJA8|uniprotkb:Q5ST26|uniprotkb:Q6LA73|uniprotkb:Q6NXR9|uniprotkb:Q9BZY6|uniprotkb:Q9UJL3|ensembl:ENSP00000383555|ensembl:ENSP00000392787|ensembl:ENSP00000405229|ensembl:ENSP00000414793|ensembl:ENSP00000366404	psi-mi:smp1_yeast(display_long)|uniprotkb:YBR1245(orf name)|uniprotkb:YBR182C(locus name)|uniprotkb:SMP1(gene name)|psi-mi:SMP1(display_short)	psi-mi:tri27_human(display_long)|uniprotkb:TRIM27(gene name)|psi-mi:TRIM27(display_short)|uniprotkb:RNF76(gene name synonym)|uniprotkb:RFP(gene name synonym)|uniprotkb:Ret finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 27(gene name synonym)|uniprotkb:RING finger protein 76(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM27(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11556973|imex:IM-24995-4573	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009741.3|sgd:S000000386|interpro:IPR002100(Transcription factor, MADS-box)|ensemblfungi:YBR182C(gene)|ensemblfungi:YBR182C_mRNA(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|reactome:R-SCE-525793|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR033896|interpro:IPR036879|sgd:YBR182C(identity)	refseq:NP_006501.1|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0090281"(negative regulation of calcium ion import)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR020457|interpro:IPR035791|interpro:IPR043136|mint:P14373|reactome:R-HSA-3232142|reactome:R-HSA-9635465|reactome:R-HSA-8948751|ensembl:ENSG00000204713(gene)|ensembl:ENSG00000215641(gene)|ensembl:ENSG00000229006(gene)|ensembl:ENSG00000234495(gene)|ensembl:ENSG00000237071(gene)|ensembl:ENST00000377199(transcript)|ensembl:ENST00000400720(transcript)|ensembl:ENST00000431123(transcript)|ensembl:ENST00000435528(transcript)|ensembl:ENST00000437160(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001650"(fibrillar center)|go:"GO:0002820"(negative regulation of adaptive immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|entrezgene/locuslink:5987(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:+iBP5NzZkrXnslYfo1RDMrlTAIQ559292	rogid:dsfH5OUghD8KSaTz1SFw9OYVTK49606	intact-crc:6003456C7E9EF8BA|rigid:t/9+zqK7MrZBLRPnAemxMVxZ3lo	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38182	uniprotkb:O43379	intact:EBI-2684|uniprotkb:D6VPS5|ensemblfungi:YBL078C	intact:EBI-714790|uniprotkb:Q63HP9|uniprotkb:Q659D7|uniprotkb:Q8NBF7|uniprotkb:Q96AD9|intact:EBI-2563293|ensembl:ENSP00000270301	psi-mi:atg8_yeast(display_long)|uniprotkb:ATG8(gene name)|psi-mi:ATG8(display_short)|uniprotkb:APG8(gene name synonym)|uniprotkb:AUT7(gene name synonym)|uniprotkb:YBL078C(locus name)|uniprotkb:YBL0732(orf name)|uniprotkb:CVT5(gene name synonym)|uniprotkb:Autophagy-related ubiquitin-like modifier ATG8(gene name synonym)|uniprotkb:Cytoplasm to vacuole targeting protein 5(gene name synonym)	psi-mi:wdr62_human(display_long)|uniprotkb:WDR62(gene name)|psi-mi:WDR62(display_short)|uniprotkb:C19orf14(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11557087|imex:IM-24995-4585	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000000174|refseq:NP_009475.1|dip:DIP-1197N|mint:P38182|ensemblfungi:YBL078C(gene)|ensemblfungi:YBL078C_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006914"(autophagy)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0008429"(phosphatidylethanolamine binding)|go:"GO:0016236"(macroautophagy)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0031386"(protein tag)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0033110"(Cvt vesicle membrane)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0034629"|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|go:"GO:0061025"(membrane fusion)|go:"GO:0061709"(reticulophagy)|go:"GO:0071211"(protein targeting to vacuole involved in autophagy)|go:"GO:0120095"(vacuole-isolation membrane contact site)|go:"GO:1905153"(regulation of membrane invagination)|interpro:IPR004241("Light chain 3 (LC3)")|interpro:IPR029071|rcsb pdb:2KQ7|rcsb pdb:2KWC|rcsb pdb:2LI5|rcsb pdb:2ZPN|rcsb pdb:3RUI|rcsb pdb:3VH3|rcsb pdb:3VH4|rcsb pdb:3VXW|rcsb pdb:5YEC|rcsb pdb:6AAG|rcsb pdb:6WY6|rcsb pdb:7BRN|reactome:R-SCE-1632852|reactome:R-SCE-8854214|reactome:R-SCE-8934903|sgd:YBL078C(identity)	go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007099"(centriole replication)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0022008"(neurogenesis)|go:"GO:0034451"(centriolar satellite)|interpro:IPR001680(WD40 repeat)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR024977|interpro:IPR036322|mint:O43379|go:"GO:0005813"(centrosome)|ensembl:ENSG00000075702(gene)|ensembl:ENST00000270301(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|refseq:NP_001077430.1|refseq:NP_775907.4|refseq:XP_016882154.1|dip:DIP-56792N|entrezgene/locuslink:284403(identity)	-	crc64:1246CEFF5A038819	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:UlmpBW3JgdYFHLkZCQeJeb7DpK4559292	rogid:bKUivd80luQPFZHsU9mDdwyGwi89606	intact-crc:59986ECD042D6CD7|rigid:Mf1TAEYS+GdwEh4qdc1A2+skDkQ	false	-	sufficient binding region:889-1518	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O43765	uniprotkb:P38168	intact:EBI-347996|ensembl:ENSP00000221566|ensembl:ENSP00000503397|ensembl:ENSP00000504495|uniprotkb:Q9BTZ9|intact:EBI-1045243|uniprotkb:Q6FIA9|uniprotkb:D6W610	intact:EBI-21355|ensemblfungi:YBL100C	psi-mi:sgta_human(display_long)|uniprotkb:SGTA(gene name)|psi-mi:SGTA(display_short)|uniprotkb:SGT(gene name synonym)|uniprotkb:Alpha-SGT(gene name synonym)|uniprotkb:Vpu-binding protein(gene name synonym)|uniprotkb:SGT1(gene name synonym)	psi-mi:ybk0_yeast(display_long)|uniprotkb:YBL0826(orf name)|uniprotkb:YBL100C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11557078|imex:IM-24995-4584	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:4CPG|rcsb pdb:4GOD|rcsb pdb:4GOE|rcsb pdb:4GOF|reactome:R-HSA-9609523|rcsb pdb:2VYI|ensembl:ENSG00000104969(gene)|ensembl:ENST00000221566(transcript)|ensembl:ENST00000676943(transcript)|ensembl:ENST00000677149(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072380"(TRC complex)|go:"GO:0098850"(extrinsic component of synaptic vesicle membrane)|go:"GO:1903070"(negative regulation of ER-associated ubiquitin-dependent protein catabolic process)|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)|go:"GO:1903646"(positive regulation of chaperone-mediated protein folding)|go:"GO:1904288"(BAT3 complex binding)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR032374|mint:O43765|refseq:XP_011526480.1|refseq:NP_003012.1|entrezgene/locuslink:6449(identity)	sgd:S000000196|dip:DIP-5675N|ensemblfungi:YBL100C(gene)|ensemblfungi:YBL100C_mRNA(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|sgd:YBL100C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:r/Cyj4UJk/cS8QdrbjhTZMPCigI9606	rogid:gPuMXsZP2fRnDh4HhKc6uX1tT8M559292	intact-crc:9FB3FE99AA125790|rigid:3OnFZnXxD10R/tRtUYSZvlE7F5g	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38166	uniprotkb:Q15437	intact:EBI-17046|uniprotkb:D6VPQ1|ensemblfungi:YBL102W	intact:EBI-742673|uniprotkb:Q5W183|uniprotkb:Q9BS15|uniprotkb:Q9BSI2|uniprotkb:Q9H1D7|intact:EBI-1048165|uniprotkb:Q503A9|uniprotkb:D3DW33|ensembl:ENSP00000262544|ensembl:ENSP00000338844|ensembl:ENSP00000366685|ensembl:ENSP00000497473	psi-mi:sft2_yeast(display_long)|uniprotkb:YBL0812(orf name)|uniprotkb:YBL102W(locus name)|uniprotkb:SFT2(gene name)|psi-mi:SFT2(display_short)	psi-mi:sc23b_human(display_long)|uniprotkb:SEC23-related protein B(gene name synonym)|uniprotkb:SEC23B(gene name)|psi-mi:SEC23B(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11557068|imex:IM-24995-4583	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YBL102W(gene)|ensemblfungi:YBL102W_mRNA(transcript)|go:"GO:0000138"(Golgi trans cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005829"(cytosol)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|interpro:IPR007305(Got1-like protein)|interpro:IPR011691(SFT2-like)|refseq:NP_009448.1|sgd:S000000198|dip:DIP-1865N|mint:P38166|sgd:YBL102W(identity)	refseq:NP_001166216.1|refseq:NP_006354.2|refseq:NP_116780.1|refseq:NP_116781.1|ensembl:ENSG00000101310(gene)|ensembl:ENST00000262544(transcript)|ensembl:ENST00000336714(transcript)|ensembl:ENST00000377465(transcript)|ensembl:ENST00000650089(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008270"(zinc ion binding)|go:"GO:0012505"(endomembrane system)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0090110"(COPII-coated vesicle cargo loading)|go:"GO:0070971"(endoplasmic reticulum exit site)|interpro:IPR006895(Zinc finger, Sec23/Sec24-type)|interpro:IPR006896(Sec23/Sec24 trunk region)|interpro:IPR006900(Sec23/Sec24 helical region)|interpro:IPR007123(Gelsolin region)|interpro:IPR012990(Sec23/Sec24 beta-sandwich)|interpro:IPR029006|interpro:IPR036174|interpro:IPR036175|interpro:IPR036180|interpro:IPR036465|interpro:IPR037364|interpro:IPR037550|mint:Q15437|refseq:XP_016883082.1|entrezgene/locuslink:10483(identity)	-	crc64:1BF971749814382C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:tGTSgSqEOsu/4dXIp31UzvtkyKs559292	rogid:+3KZ/1jjziSgJRcr81Axquofkl49606	intact-crc:7EB87716F7A8E6A7|rigid:s/Px0A+1Hb5Mw2Fxv5DKdhsoRtA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38151	uniprotkb:Q9HCM9-2	intact:EBI-12968|uniprotkb:D6VQM8|ensemblfungi:YBR233W	intact:EBI-11523450|ensembl:ENSP00000365847|ensembl:ENSP00000373095|ensembl:ENSP00000373097|ensembl:ENSP00000379797|ensembl:ENSP00000379800|ensembl:ENSP00000383486|ensembl:ENSP00000387445|ensembl:ENSP00000389198|ensembl:ENSP00000389852|ensembl:ENSP00000392130|ensembl:ENSP00000394353|ensembl:ENSP00000396986|ensembl:ENSP00000398956|ensembl:ENSP00000401071|ensembl:ENSP00000401184|ensembl:ENSP00000404340|ensembl:ENSP00000404904|ensembl:ENSP00000411582|ensembl:ENSP00000412743|ensembl:ENSP00000414525|ensembl:ENSP00000415259	psi-mi:pbp2_yeast(display_long)|uniprotkb:YBR1531(orf name)|uniprotkb:YBR233W(locus name)|uniprotkb:PBP2(gene name)|psi-mi:PBP2(display_short)	psi-mi:q9hcm9-2(display_long)|uniprotkb:TRIM39(gene name)|psi-mi:TRIM39(display_short)|uniprotkb:RING finger protein 23(gene name synonym)|uniprotkb:RNF23(gene name synonym)|uniprotkb:TFP(gene name synonym)|uniprotkb:Testis-abundant finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 39(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM39(gene name synonym)|uniprotkb:TIM39beta(isoform synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11557058|imex:IM-24995-4582	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000000437|refseq:NP_009792.3|dip:DIP-4947N|ensemblfungi:YBR233W(gene)|ensemblfungi:YBR233W_mRNA(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0051252"(regulation of RNA metabolic process)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR036612|sgd:YBR233W(identity)	intact:EBI-739510(isoform-parent)|ensembl:ENSG00000204599(gene)|ensembl:ENSG00000206495(gene)|ensembl:ENSG00000224994(gene)|ensembl:ENSG00000226437(gene)|ensembl:ENSG00000229929(gene)|ensembl:ENSG00000230308(gene)|ensembl:ENSG00000232839(gene)|ensembl:ENST00000376659(transcript)|ensembl:ENST00000383601(transcript)|ensembl:ENST00000383603(transcript)|ensembl:ENST00000396548(transcript)|ensembl:ENST00000396551(transcript)|ensembl:ENST00000400644(transcript)|ensembl:ENST00000414015(transcript)|ensembl:ENST00000419790(transcript)|ensembl:ENST00000430502(transcript)|ensembl:ENST00000431272(transcript)|ensembl:ENST00000433900(transcript)|ensembl:ENST00000438076(transcript)|ensembl:ENST00000438859(transcript)|ensembl:ENST00000440117(transcript)|ensembl:ENST00000443109(transcript)|ensembl:ENST00000446397(transcript)|ensembl:ENST00000449318(transcript)|ensembl:ENST00000450778(transcript)|ensembl:ENST00000451132(transcript)|ensembl:ENST00000452705(transcript)|ensembl:ENST00000458607(transcript)|uniprotkb:Q9HCM9-2(isoform-parent)|entrezgene/locuslink:56658(identity)	-	crc64:638846509BCE1840	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:zcN9K+pivnit4l3Cl75wfk5F4VI559292	rogid:UfSn2+IVRxtGomVeDGdZpL7mz5I9606	intact-crc:6BC5203FAB6C6CC6|rigid:bVlRgMoN5MAv7jTlzTgLikI5FNw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38151	uniprotkb:Q9HAN9	intact:EBI-12968|uniprotkb:D6VQM8|ensemblfungi:YBR233W	intact:EBI-3917542|uniprotkb:Q8TAE9|uniprotkb:Q9H6B6|uniprotkb:Q9H247|uniprotkb:B1AN63|ensembl:ENSP00000366410|ensembl:ENSP00000435134	psi-mi:pbp2_yeast(display_long)|uniprotkb:YBR1531(orf name)|uniprotkb:YBR233W(locus name)|uniprotkb:PBP2(gene name)|psi-mi:PBP2(display_short)	psi-mi:nmna1_human(display_long)|uniprotkb:NMNAT1(gene name)|psi-mi:NMNAT1(display_short)|uniprotkb:NMNAT(gene name synonym)|uniprotkb:Nicotinate-nucleotide adenylyltransferase 1(gene name synonym)|uniprotkb:Nicotinamide-nucleotide adenylyltransferase 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11557049|imex:IM-24995-4581	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000000437|refseq:NP_009792.3|dip:DIP-4947N|ensemblfungi:YBR233W(gene)|ensemblfungi:YBR233W_mRNA(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0051252"(regulation of RNA metabolic process)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR036612|sgd:YBR233W(identity)	refseq:NP_001284707.1|refseq:NP_073624.2|ensembl:ENSG00000173614(gene)|ensembl:ENST00000377205(transcript)|ensembl:ENST00000462686(transcript)|go:"GO:0000309"(nicotinamide-nucleotide adenylyltransferase activity)|go:"GO:0004515"(nicotinate-nucleotide adenylyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0009165"(nucleotide biosynthetic process)|go:"GO:0009435"(NAD biosynthetic process)|go:"GO:0009611"(response to wounding)|go:"GO:0016604"(nuclear body)|go:"GO:0042802"(identical protein binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:1902511"(negative regulation of apoptotic DNA fragmentation)|go:"GO:1990966"(ATP generation from poly-ADP-D-ribose)|interpro:IPR004821(Cytidyltransferase-related)|interpro:IPR005248(Probable nicotinate-nucleotide adenylyltransferase)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|mint:Q9HAN9|rcsb pdb:1GZU|rcsb pdb:1KKU|rcsb pdb:1KQN|rcsb pdb:1KQO|rcsb pdb:1KR2|reactome:R-HSA-196807|refseq:XP_016857596.1|dip:DIP-60881N|entrezgene/locuslink:64802(identity)	-	crc64:638846509BCE1840	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:zcN9K+pivnit4l3Cl75wfk5F4VI559292	rogid:KwV9lz04z3ptlVpKu3b534Yekpc9606	intact-crc:70BDA3DBFD702B69|rigid:ueKN62aID4CjKR81IgQzdYM3Tk8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38151	uniprotkb:Q96PU8	intact:EBI-12968|uniprotkb:D6VQM8|ensemblfungi:YBR233W	intact:EBI-945792|uniprotkb:Q2I375|uniprotkb:Q5MJQ1|uniprotkb:Q969L9|uniprotkb:Q96EJ3|uniprotkb:Q96KA3|uniprotkb:Q96PU6|uniprotkb:Q96PU7|uniprotkb:Q9P0X6|uniprotkb:Q9P0X7|uniprotkb:Q9P0X8|uniprotkb:Q9P0X9|uniprotkb:Q9P0Y0|uniprotkb:Q9P0Y1|ensembl:ENSP00000355094	psi-mi:pbp2_yeast(display_long)|uniprotkb:YBR1531(orf name)|uniprotkb:YBR233W(locus name)|uniprotkb:PBP2(gene name)|psi-mi:PBP2(display_short)	psi-mi:qki_human(display_long)|uniprotkb:QKI(gene name)|psi-mi:QKI(display_short)|uniprotkb:HKQ(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11557040|imex:IM-24995-4580	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000000437|refseq:NP_009792.3|dip:DIP-4947N|ensemblfungi:YBR233W(gene)|ensemblfungi:YBR233W_mRNA(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0051252"(regulation of RNA metabolic process)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR036612|sgd:YBR233W(identity)	refseq:NP_006766.1|refseq:NP_996735.1|refseq:NP_996736.1|refseq:NP_996737.1|refseq:NP_001288014.1|refseq:XP_011534561.1|ensembl:ENSG00000112531(gene)|ensembl:ENST00000361752(transcript)|go:"GO:0001570"(vasculogenesis)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0006417"(regulation of translation)|go:"GO:0007286"(spermatid development)|go:"GO:0008380"(RNA splicing)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0042552"(myelination)|go:"GO:0042692"(muscle cell differentiation)|go:"GO:0042759"(long-chain fatty acid biosynthetic process)|go:"GO:0045202"(synapse)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0051028"(mRNA transport)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR032367|interpro:IPR032377|interpro:IPR036612|mint:Q96PU8|rcsb pdb:4JVH|reactome:R-HSA-6802952|entrezgene/locuslink:9444(identity)	-	crc64:638846509BCE1840	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:zcN9K+pivnit4l3Cl75wfk5F4VI559292	rogid:7dcw5OyNAhQTE+yTch3qbSlZJdE9606	intact-crc:940E75833AF6C35B|rigid:LpPFQcO9qpi9sQJVGxaytAmOhKc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8N6L0	uniprotkb:P38206	intact:EBI-749265|uniprotkb:Q96MC3|ensembl:ENSP00000404220	intact:EBI-15028|uniprotkb:Q05814|uniprotkb:D6VPY0|ensemblfungi:YBL020W	psi-mi:kash5_human(display_long)|uniprotkb:KASH5(gene name)|psi-mi:KASH5(display_short)|uniprotkb:CCDC155(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 155(gene name synonym)|uniprotkb:KASH domain-containing protein 5(gene name synonym)	psi-mi:rft1_yeast(display_long)|uniprotkb:RFT1(gene name)|psi-mi:RFT1(display_short)|uniprotkb:YBL020W(locus name)|uniprotkb:YBL0442(orf name)|uniprotkb:Requiring fifty-three protein 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11557162|imex:IM-24995-4593	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_653289.3|ensembl:ENSG00000161609(gene)|ensembl:ENST00000447857(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034397"(telomere localization)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051225"(spindle assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0090172"(microtubule cytoskeleton organization involved in homologous chromosome segregation)|go:"GO:0090220"(chromosome localization to nuclear envelope involved in homologous chromosome segregation)|go:"GO:0090619"(meiotic spindle pole)|interpro:IPR011992(EF-Hand type)|interpro:IPR028168|interpro:IPR028170|interpro:IPR039508|mint:Q8N6L0|rcsb pdb:6R2I|rcsb pdb:6WMF|entrezgene/locuslink:147872(identity)	refseq:NP_009533.1|sgd:S000000116|ensemblfungi:YBL020W(gene)|ensemblfungi:YBL020W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006488"(dolichol-linked oligosaccharide biosynthetic process)|go:"GO:0008643"(carbohydrate transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034202"(glycolipid floppase activity)|go:"GO:0034203"(glycolipid translocation)|interpro:IPR007594(RFT1)|dip:DIP-3885N|mint:P38206|sgd:YBL020W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Wl9L7AcvDHCZuKjYLn8QgGIbZTc9606	rogid:nBfsGoVh81NwPryblR48jOVVQsU559292	intact-crc:6736230EF9284B73|rigid:+mKcNMiv2h/xD/MRZ7N4T/Iqe50	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38206	uniprotkb:Q8IV61	intact:EBI-15028|uniprotkb:Q05814|uniprotkb:D6VPY0|ensemblfungi:YBL020W	intact:EBI-1047876|uniprotkb:O94931|uniprotkb:Q53SD7|uniprotkb:D6W583|ensembl:ENSP00000384192|ensembl:ENSP00000385886	psi-mi:rft1_yeast(display_long)|uniprotkb:RFT1(gene name)|psi-mi:RFT1(display_short)|uniprotkb:YBL020W(locus name)|uniprotkb:YBL0442(orf name)|uniprotkb:Requiring fifty-three protein 1(gene name synonym)	psi-mi:grp3_human(display_long)|uniprotkb:Calcium and DAG-regulated guanine nucleotide exchange factor III(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor for Rap1(gene name synonym)|uniprotkb:RASGRP3(gene name)|psi-mi:RASGRP3(display_short)|uniprotkb:GRP3(gene name synonym)|uniprotkb:KIAA0846(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11557153|imex:IM-24995-4592	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009533.1|sgd:S000000116|ensemblfungi:YBL020W(gene)|ensemblfungi:YBL020W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006488"(dolichol-linked oligosaccharide biosynthetic process)|go:"GO:0008643"(carbohydrate transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034202"(glycolipid floppase activity)|go:"GO:0034203"(glycolipid translocation)|interpro:IPR007594(RFT1)|dip:DIP-3885N|mint:P38206|sgd:YBL020W(identity)	refseq:NP_001132960.1|refseq:NP_056191.1|refseq:NP_733772.1|refseq:XP_011531048.1|refseq:XP_011531049.1|refseq:XP_016859248.1|refseq:XP_016859249.1|refseq:XP_016859250.1|refseq:XP_016859251.1|refseq:XP_016859252.1|refseq:XP_011531050.2|ensembl:ENSG00000152689(gene)|ensembl:ENST00000402538(transcript)|ensembl:ENST00000403687(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0019900"(kinase binding)|go:"GO:0019992"(diacylglycerol binding)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR000651(Guanine nucleotide exchange factor for Ras-like GTPases, N-terminal)|interpro:IPR001895(Guanine-nucleotide dissociation stimulator CDC25)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008937(Ras guanine nucleotide exchange factor)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR020454|interpro:IPR023578|interpro:IPR029645|interpro:IPR036964|reactome:R-HSA-1169092|reactome:R-HSA-5673001|refseq:XP_005264303.1|entrezgene/locuslink:25780(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:nBfsGoVh81NwPryblR48jOVVQsU559292	rogid:yO4CIzGZmGYS124YcNmFKQh7+bo9606	intact-crc:1ED3C403C8A21FEF|rigid:ni8QLeHB1RRrD7d0Bqy0qtRmISk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P14373	uniprotkb:P38203	intact:EBI-719493|uniprotkb:A2BE15|uniprotkb:Q5RJA8|uniprotkb:Q5ST26|uniprotkb:Q6LA73|uniprotkb:Q6NXR9|uniprotkb:Q9BZY6|uniprotkb:Q9UJL3|ensembl:ENSP00000383555|ensembl:ENSP00000392787|ensembl:ENSP00000405229|ensembl:ENSP00000414793|ensembl:ENSP00000366404	intact:EBI-180|ensemblfungi:YBL026W|uniprotkb:D6VPX4	psi-mi:tri27_human(display_long)|uniprotkb:TRIM27(gene name)|psi-mi:TRIM27(display_short)|uniprotkb:RNF76(gene name synonym)|uniprotkb:RFP(gene name synonym)|uniprotkb:Ret finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 27(gene name synonym)|uniprotkb:RING finger protein 76(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM27(gene name synonym)	psi-mi:lsm2_yeast(display_long)|uniprotkb:LSM2(gene name)|psi-mi:LSM2(display_short)|uniprotkb:Small nuclear ribonucleoprotein D homolog SNP3(gene name synonym)|uniprotkb:SMX5(gene name synonym)|uniprotkb:SNP3(gene name synonym)|uniprotkb:YBL0425(orf name)|uniprotkb:YBL026W(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11557144|imex:IM-24995-4591	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006501.1|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0090281"(negative regulation of calcium ion import)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR020457|interpro:IPR035791|interpro:IPR043136|mint:P14373|reactome:R-HSA-3232142|reactome:R-HSA-9635465|reactome:R-HSA-8948751|ensembl:ENSG00000204713(gene)|ensembl:ENSG00000215641(gene)|ensembl:ENSG00000229006(gene)|ensembl:ENSG00000234495(gene)|ensembl:ENSG00000237071(gene)|ensembl:ENST00000377199(transcript)|ensembl:ENST00000400720(transcript)|ensembl:ENST00000431123(transcript)|ensembl:ENST00000435528(transcript)|ensembl:ENST00000437160(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001650"(fibrillar center)|go:"GO:0002820"(negative regulation of adaptive immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|entrezgene/locuslink:5987(identity)	refseq:NP_009527.1|sgd:S000000122|go:"GO:0005688"(U6 snRNP)|go:"GO:0005730"(nucleolus)|go:"GO:0005732"("sno(s)RNA-containing ribonucleoprotein complex")|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0008033"(tRNA processing)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990726"(Lsm1-7-Pat1 complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR016654(U6 snRNA-associated Sm-like protein LSm2)|rcsb pdb:3JCM|rcsb pdb:4C8Q|rcsb pdb:4C92|rcsb pdb:4M75|rcsb pdb:4M77|ensemblfungi:YBL026W(gene)|ensemblfungi:YBL026W_mRNA(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|mint:P38203|dip:DIP-794N|rcsb pdb:4M78|rcsb pdb:4M7A|rcsb pdb:4M7D|rcsb pdb:4N0A|rcsb pdb:5GAN|rcsb pdb:5NRL|rcsb pdb:5VSU|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:6ASO|reactome:R-SCE-430039|sgd:YBL026W(identity)	-	-	crc64:C23856268CEE92E2	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:dsfH5OUghD8KSaTz1SFw9OYVTK49606	rogid:3E5c7Mzg433awFPmamamsKjtJmY559292	intact-crc:7CA9D518842C33FD|rigid:hXyimIo/ILQQZTcsfdF11Q+LFPc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38182	uniprotkb:Q9UH92-3	intact:EBI-2684|uniprotkb:D6VPS5|ensemblfungi:YBL078C	intact:EBI-8852072|ensembl:ENSP00000416627	psi-mi:atg8_yeast(display_long)|uniprotkb:ATG8(gene name)|psi-mi:ATG8(display_short)|uniprotkb:APG8(gene name synonym)|uniprotkb:AUT7(gene name synonym)|uniprotkb:YBL078C(locus name)|uniprotkb:YBL0732(orf name)|uniprotkb:CVT5(gene name synonym)|uniprotkb:Autophagy-related ubiquitin-like modifier ATG8(gene name synonym)|uniprotkb:Cytoplasm to vacuole targeting protein 5(gene name synonym)	psi-mi:q9uh92-3(display_long)|uniprotkb:MLX(gene name)|psi-mi:MLX(display_short)|uniprotkb:BHLHD13(gene name synonym)|uniprotkb:TCFL4(gene name synonym)|uniprotkb:Class D basic helix-loop-helix protein 13(gene name synonym)|uniprotkb:Max-like bHLHZip protein(gene name synonym)|uniprotkb:Protein BigMax(gene name synonym)|uniprotkb:Transcription factor-like protein 4(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11557135|imex:IM-24995-4590	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000000174|refseq:NP_009475.1|dip:DIP-1197N|mint:P38182|ensemblfungi:YBL078C(gene)|ensemblfungi:YBL078C_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006914"(autophagy)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0008429"(phosphatidylethanolamine binding)|go:"GO:0016236"(macroautophagy)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0031386"(protein tag)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0033110"(Cvt vesicle membrane)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0034629"|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|go:"GO:0061025"(membrane fusion)|go:"GO:0061709"(reticulophagy)|go:"GO:0071211"(protein targeting to vacuole involved in autophagy)|go:"GO:0120095"(vacuole-isolation membrane contact site)|go:"GO:1905153"(regulation of membrane invagination)|interpro:IPR004241("Light chain 3 (LC3)")|interpro:IPR029071|rcsb pdb:2KQ7|rcsb pdb:2KWC|rcsb pdb:2LI5|rcsb pdb:2ZPN|rcsb pdb:3RUI|rcsb pdb:3VH3|rcsb pdb:3VH4|rcsb pdb:3VXW|rcsb pdb:5YEC|rcsb pdb:6AAG|rcsb pdb:6WY6|rcsb pdb:7BRN|reactome:R-SCE-1632852|reactome:R-SCE-8854214|reactome:R-SCE-8934903|sgd:YBL078C(identity)	ensembl:ENSG00000108788(gene)|ensembl:ENST00000435881(transcript)|intact:EBI-741109(isoform-parent)|uniprotkb:Q9UH92-3(isoform-parent)|entrezgene/locuslink:6945(identity)	-	crc64:1246CEFF5A038819	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:UlmpBW3JgdYFHLkZCQeJeb7DpK4559292	rogid:M3gABDaYvwenMrLrp6Tbpl6ZU909606	intact-crc:F201E131A3F6553B|rigid:EWuh8wGIWzo/TY2TXJgjg7rbuHc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96GX9	uniprotkb:P38182	intact:EBI-359248|ensembl:ENSP00000379133|intact:EBI-2848621|uniprotkb:Q6PJX6|uniprotkb:Q8WVU2|uniprotkb:Q96HK2|uniprotkb:Q9Y318|uniprotkb:A8K9D3	intact:EBI-2684|uniprotkb:D6VPS5|ensemblfungi:YBL078C	psi-mi:mtnb_human(display_long)|uniprotkb:APIP(gene name)|psi-mi:APIP(display_short)|uniprotkb:CGI-29(orf name)|uniprotkb:APAF1-interacting protein(gene name synonym)	psi-mi:atg8_yeast(display_long)|uniprotkb:ATG8(gene name)|psi-mi:ATG8(display_short)|uniprotkb:APG8(gene name synonym)|uniprotkb:AUT7(gene name synonym)|uniprotkb:YBL078C(locus name)|uniprotkb:YBL0732(orf name)|uniprotkb:CVT5(gene name synonym)|uniprotkb:Autophagy-related ubiquitin-like modifier ATG8(gene name synonym)|uniprotkb:Cytoplasm to vacuole targeting protein 5(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11557125|imex:IM-24995-4589	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000149089(gene)|ensembl:ENST00000395787(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019284"(L-methionine salvage from S-adenosylmethionine)|go:"GO:0019509"(L-methionine salvage from methylthioadenosine)|refseq:NP_057041.2|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0046570"(methylthioribulose 1-phosphate dehydratase activity)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0070269"(pyroptosis)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|interpro:IPR001303(Class II aldolase/adducin, N-terminal)|interpro:IPR017714(Methylthioribulose-1-phosphate dehydratase)|interpro:IPR027514|interpro:IPR036409|rcsb pdb:4M6R|reactome:R-HSA-111458|reactome:R-HSA-1237112|reactome:R-HSA-9627069|entrezgene/locuslink:51074(identity)	sgd:S000000174|refseq:NP_009475.1|dip:DIP-1197N|mint:P38182|ensemblfungi:YBL078C(gene)|ensemblfungi:YBL078C_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006914"(autophagy)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0008429"(phosphatidylethanolamine binding)|go:"GO:0016236"(macroautophagy)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0031386"(protein tag)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0033110"(Cvt vesicle membrane)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0034629"|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|go:"GO:0061025"(membrane fusion)|go:"GO:0061709"(reticulophagy)|go:"GO:0071211"(protein targeting to vacuole involved in autophagy)|go:"GO:0120095"(vacuole-isolation membrane contact site)|go:"GO:1905153"(regulation of membrane invagination)|interpro:IPR004241("Light chain 3 (LC3)")|interpro:IPR029071|rcsb pdb:2KQ7|rcsb pdb:2KWC|rcsb pdb:2LI5|rcsb pdb:2ZPN|rcsb pdb:3RUI|rcsb pdb:3VH3|rcsb pdb:3VH4|rcsb pdb:3VXW|rcsb pdb:5YEC|rcsb pdb:6AAG|rcsb pdb:6WY6|rcsb pdb:7BRN|reactome:R-SCE-1632852|reactome:R-SCE-8854214|reactome:R-SCE-8934903|sgd:YBL078C(identity)	-	-	crc64:1246CEFF5A038819	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:k+IcLEB6jPgZW0Zl597PZyGbHH49606	rogid:UlmpBW3JgdYFHLkZCQeJeb7DpK4559292	intact-crc:993CE45C07174977|rigid:wgy+lOhNd+Qn5eTzjT8SW6Hbl6g	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38182	uniprotkb:Q92609	intact:EBI-2684|uniprotkb:D6VPS5|ensemblfungi:YBL078C	intact:EBI-742381|uniprotkb:A6NP25|intact:EBI-28978959|ensembl:ENSP00000253692|ensembl:ENSP00000398127|uniprotkb:C9JP52	psi-mi:atg8_yeast(display_long)|uniprotkb:ATG8(gene name)|psi-mi:ATG8(display_short)|uniprotkb:APG8(gene name synonym)|uniprotkb:AUT7(gene name synonym)|uniprotkb:YBL078C(locus name)|uniprotkb:YBL0732(orf name)|uniprotkb:CVT5(gene name synonym)|uniprotkb:Autophagy-related ubiquitin-like modifier ATG8(gene name synonym)|uniprotkb:Cytoplasm to vacuole targeting protein 5(gene name synonym)	psi-mi:tbcd5_human(display_long)|uniprotkb:TBC1D5(gene name)|psi-mi:TBC1D5(display_short)|uniprotkb:KIAA0210(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11557116|imex:IM-24995-4588	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000000174|refseq:NP_009475.1|dip:DIP-1197N|mint:P38182|ensemblfungi:YBL078C(gene)|ensemblfungi:YBL078C_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006914"(autophagy)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0008429"(phosphatidylethanolamine binding)|go:"GO:0016236"(macroautophagy)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0031386"(protein tag)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0033110"(Cvt vesicle membrane)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0034629"|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|go:"GO:0061025"(membrane fusion)|go:"GO:0061709"(reticulophagy)|go:"GO:0071211"(protein targeting to vacuole involved in autophagy)|go:"GO:0120095"(vacuole-isolation membrane contact site)|go:"GO:1905153"(regulation of membrane invagination)|interpro:IPR004241("Light chain 3 (LC3)")|interpro:IPR029071|rcsb pdb:2KQ7|rcsb pdb:2KWC|rcsb pdb:2LI5|rcsb pdb:2ZPN|rcsb pdb:3RUI|rcsb pdb:3VH3|rcsb pdb:3VH4|rcsb pdb:3VXW|rcsb pdb:5YEC|rcsb pdb:6AAG|rcsb pdb:6WY6|rcsb pdb:7BRN|reactome:R-SCE-1632852|reactome:R-SCE-8854214|reactome:R-SCE-8934903|sgd:YBL078C(identity)	ensembl:ENSP00000253692|ensembl:ENSP00000398127|ensembl:ENSP00000402935|ensembl:ENST00000446818|refseq:NP_055559.1|refseq:XP_011532586.1|refseq:XP_011532583.1|refseq:XP_011532585.1|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005776"(autophagosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006914"(autophagy)|go:"GO:0010008"(endosome membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0030904"(retromer complex)|go:"GO:0035612"(AP-2 adaptor complex binding)|ensembl:ENSG00000131374(gene)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042594"(response to starvation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:1905394"(retromer complex binding)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR035969|mint:Q92609|rcsb pdb:5GTU|ensembl:ENST00000253692(transcript)|ensembl:ENST00000429383(transcript)|go:"GO:0002092"(positive regulation of receptor internalization)|refseq:NP_001127853.1|refseq:XP_006713493.1|refseq:XP_016863041.1|refseq:XP_016863042.1|refseq:XP_016863043.1|refseq:XP_016863044.1|refseq:XP_016863045.1|refseq:XP_016863046.1|entrezgene/locuslink:9779(identity)	-	crc64:1246CEFF5A038819	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:UlmpBW3JgdYFHLkZCQeJeb7DpK4559292	rogid:GZ7WP4suMiSPSAJK0TZWQMQZxzU9606	intact-crc:2758F917CB9C9DEA|rigid:7v+nlQJThCowWc7ZH5aEqne9ilQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12983	uniprotkb:P38182	intact:EBI-749464|uniprotkb:O14620|uniprotkb:Q96GP0|intact:EBI-28978130|ensembl:ENSP00000357625	intact:EBI-2684|uniprotkb:D6VPS5|ensemblfungi:YBL078C	psi-mi:bnip3_human(display_long)|uniprotkb:BNIP3(gene name)|psi-mi:BNIP3(display_short)|uniprotkb:NIP3(gene name synonym)	psi-mi:atg8_yeast(display_long)|uniprotkb:ATG8(gene name)|psi-mi:ATG8(display_short)|uniprotkb:APG8(gene name synonym)|uniprotkb:AUT7(gene name synonym)|uniprotkb:YBL078C(locus name)|uniprotkb:YBL0732(orf name)|uniprotkb:CVT5(gene name synonym)|uniprotkb:Autophagy-related ubiquitin-like modifier ATG8(gene name synonym)|uniprotkb:Cytoplasm to vacuole targeting protein 5(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11557107|imex:IM-24995-4587	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000357625|refseq:NP_004043.3|dip:DIP-34429N|ensembl:ENSG00000176171(gene)|ensembl:ENST00000368636(transcript)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006915"(apoptotic process)|go:"GO:0008219"(cell death)|go:"GO:0009617"(response to bacterium)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010637"(negative regulation of mitochondrial fusion)|go:"GO:0010659"(cardiac muscle cell apoptotic process)|go:"GO:0010666"(positive regulation of cardiac muscle cell apoptotic process)|go:"GO:0010917"(negative regulation of mitochondrial membrane potential)|go:"GO:0010940"(positive regulation of necrotic cell death)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030425"(dendrite)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0035694"(mitochondrial protein catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043067"(regulation of programmed cell death)|go:"GO:0043068"(positive regulation of programmed cell death)|go:"GO:0043243"(positive regulation of protein-containing complex disassembly)|go:"GO:0043653"(mitochondrial fragmentation involved in apoptotic process)|go:"GO:0045837"(negative regulation of membrane potential)|go:"GO:0046902"(regulation of mitochondrial membrane permeability)|go:"GO:0048102"(autophagic cell death)|go:"GO:0048678"(response to axon injury)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0050873"(brown fat cell differentiation)|go:"GO:0051020"(GTPase binding)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051561"(positive regulation of mitochondrial calcium ion concentration)|go:"GO:0051607"(defense response to virus)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071279"(cellular response to cobalt ion)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|go:"GO:0090649"(response to oxygen-glucose deprivation)|go:"GO:0097345"(mitochondrial outer membrane permeabilization)|go:"GO:0140507"(granzyme-mediated programmed cell death signaling pathway)|go:"GO:1901998"(toxin transport)|go:"GO:1902109"(negative regulation of mitochondrial membrane permeability involved in apoptotic process)|go:"GO:1903599"(positive regulation of autophagy of mitochondrion)|go:"GO:1903715"(regulation of aerobic respiration)|go:"GO:1990144"(intrinsic apoptotic signaling pathway in response to hypoxia)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|interpro:IPR010548(BNIP3)|mint:Q12983|rcsb pdb:2J5D|rcsb pdb:2KA1|rcsb pdb:2KA2|entrezgene/locuslink:664(identity)	sgd:S000000174|refseq:NP_009475.1|dip:DIP-1197N|mint:P38182|ensemblfungi:YBL078C(gene)|ensemblfungi:YBL078C_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006914"(autophagy)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0008429"(phosphatidylethanolamine binding)|go:"GO:0016236"(macroautophagy)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0031386"(protein tag)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0033110"(Cvt vesicle membrane)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0034629"|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|go:"GO:0061025"(membrane fusion)|go:"GO:0061709"(reticulophagy)|go:"GO:0071211"(protein targeting to vacuole involved in autophagy)|go:"GO:0120095"(vacuole-isolation membrane contact site)|go:"GO:1905153"(regulation of membrane invagination)|interpro:IPR004241("Light chain 3 (LC3)")|interpro:IPR029071|rcsb pdb:2KQ7|rcsb pdb:2KWC|rcsb pdb:2LI5|rcsb pdb:2ZPN|rcsb pdb:3RUI|rcsb pdb:3VH3|rcsb pdb:3VH4|rcsb pdb:3VXW|rcsb pdb:5YEC|rcsb pdb:6AAG|rcsb pdb:6WY6|rcsb pdb:7BRN|reactome:R-SCE-1632852|reactome:R-SCE-8854214|reactome:R-SCE-8934903|sgd:YBL078C(identity)	-	crc64:53967696EDA005E2	crc64:1246CEFF5A038819	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2017/06/28	rogid:f+opYD7xO+AbYqLXXC5wh4ZJqIE9606	rogid:UlmpBW3JgdYFHLkZCQeJeb7DpK4559292	intact-crc:B08081F6478C8CEB|rigid:E/j5dg5KUIp1NpkVYjNR0weuIE0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O60238	uniprotkb:P38182	intact:EBI-849893|uniprotkb:Q5JW63|uniprotkb:Q8NF87|uniprotkb:B0AZS9|intact:EBI-28977676|ensembl:ENSP00000370003	intact:EBI-2684|uniprotkb:D6VPS5|ensemblfungi:YBL078C	psi-mi:bni3l_human(display_long)|uniprotkb:NIP3-like protein X(gene name synonym)|uniprotkb:BCL2/adenovirus E1B 19 kDa protein-interacting protein 3A(gene name synonym)|uniprotkb:Adenovirus E1B19K-binding protein B5(gene name synonym)|uniprotkb:BNIP3L(gene name)|psi-mi:BNIP3L(display_short)|uniprotkb:BNIP3A(gene name synonym)|uniprotkb:BNIP3H(gene name synonym)|uniprotkb:NIX(gene name synonym)	psi-mi:atg8_yeast(display_long)|uniprotkb:ATG8(gene name)|psi-mi:ATG8(display_short)|uniprotkb:APG8(gene name synonym)|uniprotkb:AUT7(gene name synonym)|uniprotkb:YBL078C(locus name)|uniprotkb:YBL0732(orf name)|uniprotkb:CVT5(gene name synonym)|uniprotkb:Autophagy-related ubiquitin-like modifier ATG8(gene name synonym)|uniprotkb:Cytoplasm to vacuole targeting protein 5(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11557098|imex:IM-24995-4586	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004322.1|ensembl:ENSP00000370003|ensembl:ENST00000518611|ensembl:ENSP00000429851|ensembl:ENST00000520409|ensembl:ENSP00000428597|ensembl:ENST00000523515|ensembl:ENSP00000429698|dip:DIP-35187N|refseq:NP_001317420.1|ensembl:ENSG00000104765(gene)|ensembl:ENST00000380629(transcript)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0010917"(negative regulation of mitochondrial membrane potential)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016607"(nuclear speck)|go:"GO:0031224"(intrinsic component of membrane)|go:"GO:0035694"(mitochondrial protein catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043067"(regulation of programmed cell death)|go:"GO:0051607"(defense response to virus)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0097345"(mitochondrial outer membrane permeabilization)|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1903214"(regulation of protein targeting to mitochondrion)|interpro:IPR010548(BNIP3)|mint:O60238|reactome:R-HSA-6803204|entrezgene/locuslink:665(identity)	sgd:S000000174|refseq:NP_009475.1|dip:DIP-1197N|mint:P38182|ensemblfungi:YBL078C(gene)|ensemblfungi:YBL078C_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006914"(autophagy)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0008429"(phosphatidylethanolamine binding)|go:"GO:0016236"(macroautophagy)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0031386"(protein tag)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0033110"(Cvt vesicle membrane)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0034629"|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|go:"GO:0061025"(membrane fusion)|go:"GO:0061709"(reticulophagy)|go:"GO:0071211"(protein targeting to vacuole involved in autophagy)|go:"GO:0120095"(vacuole-isolation membrane contact site)|go:"GO:1905153"(regulation of membrane invagination)|interpro:IPR004241("Light chain 3 (LC3)")|interpro:IPR029071|rcsb pdb:2KQ7|rcsb pdb:2KWC|rcsb pdb:2LI5|rcsb pdb:2ZPN|rcsb pdb:3RUI|rcsb pdb:3VH3|rcsb pdb:3VH4|rcsb pdb:3VXW|rcsb pdb:5YEC|rcsb pdb:6AAG|rcsb pdb:6WY6|rcsb pdb:7BRN|reactome:R-SCE-1632852|reactome:R-SCE-8854214|reactome:R-SCE-8934903|sgd:YBL078C(identity)	-	-	crc64:1246CEFF5A038819	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:GPDlK/z2VOVzJspIhN8XNFPSVMo9606	rogid:UlmpBW3JgdYFHLkZCQeJeb7DpK4559292	intact-crc:6512ADCD00DBD3F1|rigid:qQxn+uhb8vHnRhHxH9+ec9/R3nQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UJV3-2	uniprotkb:P38260	intact:EBI-10172526|ensembl:ENSP00000413976	intact:EBI-21563|uniprotkb:D6VQA0|ensemblfungi:YBR101C	psi-mi:q9ujv3-2(display_long)|uniprotkb:RING-type E3 ubiquitin transferase MID2(gene name synonym)|uniprotkb:FXY2(gene name synonym)|uniprotkb:Midin-2(gene name synonym)|uniprotkb:Midline defect 2(gene name synonym)|uniprotkb:Midline-2(gene name synonym)|uniprotkb:RING finger protein 60(gene name synonym)|uniprotkb:RNF60(gene name synonym)|uniprotkb:TRIM1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 1(gene name synonym)|uniprotkb:MID2(gene name)|psi-mi:MID2(display_short)	psi-mi:fes1_yeast(display_long)|uniprotkb:YBR101C(locus name)|uniprotkb:YBR0830(orf name)|uniprotkb:Factor exchange for SSA1 protein 1(gene name synonym)|uniprotkb:FES1(gene name)|psi-mi:FES1(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11557218|imex:IM-24995-4599	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-751983(isoform-parent)|uniprotkb:Q9UJV3-2(isoform-parent)|ensembl:ENSG00000080561(gene)|ensembl:ENST00000443968(transcript)|entrezgene/locuslink:11043(identity)	sgd:S000000305|refseq:NP_009659.3|mint:P38260|dip:DIP-4918N|ensemblfungi:YBR101C(gene)|ensemblfungi:YBR101C_mRNA(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006417"(regulation of translation)|go:"GO:0071629"(cytoplasm protein quality control by the ubiquitin-proteasome system)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013918(Nucleotide exchange factor Fes1)|interpro:IPR016024(Armadillo-type fold)|sgd:YBR101C(identity)	-	-	crc64:4A50D069625BA500	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:/FJ+V2H7SaWon7caUWkEkmHFVxQ9606	rogid:swXhGbIfsVTGs+eOqqViPwySpI0559292	intact-crc:B56B11B670C7088A|rigid:qDyPLF8u93/d6IjBmA8FV6aV7CI	false	sufficient binding region:21-705	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P11142	uniprotkb:P38260	intact:EBI-351896|uniprotkb:Q9H3R6|ensembl:ENSP00000227378|ensembl:ENSP00000432083|ensembl:ENSP00000437125	intact:EBI-21563|uniprotkb:D6VQA0|ensemblfungi:YBR101C	psi-mi:hsp7c_human(display_long)|uniprotkb:HSPA8(gene name)|psi-mi:HSPA8(display_short)|uniprotkb:HSC70(gene name synonym)|uniprotkb:HSP73(gene name synonym)|uniprotkb:HSPA10(gene name synonym)|uniprotkb:Heat shock 70 kDa protein 8(gene name synonym)|uniprotkb:Lipopolysaccharide-associated protein 1(gene name synonym)	psi-mi:fes1_yeast(display_long)|uniprotkb:YBR101C(locus name)|uniprotkb:YBR0830(orf name)|uniprotkb:Factor exchange for SSA1 protein 1(gene name synonym)|uniprotkb:FES1(gene name)|psi-mi:FES1(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11557207|imex:IM-24995-4598	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006588.1|refseq:NP_694881.1|refseq:XP_011541100.1|ensembl:ENSG00000109971(gene)|ensembl:ENST00000227378(transcript)|ensembl:ENST00000532636(transcript)|ensembl:ENST00000534624(transcript)|go:"GO:0000974"(Prp19 complex)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006397"(mRNA processing)|go:"GO:0006457"(protein folding)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008380"(RNA splicing)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030425"(dendrite)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042026"(protein refolding)|go:"GO:0042470"(melanosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0043195"(terminal bouton)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044829"(positive regulation by host of viral genome replication)|go:"GO:0045296"(cadherin binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0055131"(C3HC4-type RING finger domain binding)|go:"GO:0061024"(membrane organization)|go:"GO:0061202"(clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane)|go:"GO:0061635"(regulation of protein complex stability)|go:"GO:0061684"(chaperone-mediated autophagy)|go:"GO:0061738"(late endosomal microautophagy)|go:"GO:0061740"(protein targeting to lysosome involved in chaperone-mediated autophagy)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0098575"(lumenal side of lysosomal membrane)|go:"GO:0098684"(photoreceptor ribbon synapse)|go:"GO:0098690"(glycinergic synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099175"(regulation of postsynapse organization)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099634"(postsynaptic specialization membrane)|go:"GO:0101031"(chaperone complex)|go:"GO:0140545"(protein disaggregase activity)|go:"GO:0140597"(protein carrier chaperone)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902904"(negative regulation of supramolecular fiber organization)|go:"GO:1904589"(regulation of protein import)|go:"GO:1904764"(chaperone-mediated autophagy translocation complex disassembly)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1990832"(slow axonal transport)|go:"GO:1990833"(clathrin-uncoating ATPase activity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|mint:P11142|rcsb pdb:3AGY|rcsb pdb:3AGZ|rcsb pdb:3ESK|rcsb pdb:3FZF|rcsb pdb:3FZH|rcsb pdb:3FZK|rcsb pdb:3FZL|rcsb pdb:3FZM|rcsb pdb:3LDQ|rcsb pdb:3M3Z|rcsb pdb:4H5N|rcsb pdb:4H5R|rcsb pdb:4H5T|rcsb pdb:4H5V|rcsb pdb:4H5W|rcsb pdb:4HWI|rcsb pdb:4KBQ|rcsb pdb:5AQF|rcsb pdb:5AQG|rcsb pdb:5AQH|rcsb pdb:5AQI|rcsb pdb:5AQJ|rcsb pdb:5AQK|rcsb pdb:5AQL|rcsb pdb:5AQM|rcsb pdb:5AQN|rcsb pdb:5AQO|rcsb pdb:5AQP|rcsb pdb:5AQQ|rcsb pdb:5AQR|rcsb pdb:5AQS|rcsb pdb:5AQT|rcsb pdb:5AQU|rcsb pdb:5AQV|rcsb pdb:6B1I|rcsb pdb:6B1M|rcsb pdb:6B1N|rcsb pdb:6ZYJ|reactome:R-HSA-3371453|reactome:R-HSA-3371497|reactome:R-HSA-3371568|reactome:R-HSA-3371571|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-447041|reactome:R-HSA-450408|reactome:R-HSA-6785807|reactome:R-HSA-6798695|reactome:R-HSA-72163|reactome:R-HSA-8856828|reactome:R-HSA-8876725|reactome:R-HSA-888590|reactome:R-HSA-9613354|reactome:R-HSA-9613829|reactome:R-HSA-9615710|dip:DIP-32874N|entrezgene/locuslink:3312(identity)	sgd:S000000305|refseq:NP_009659.3|mint:P38260|dip:DIP-4918N|ensemblfungi:YBR101C(gene)|ensemblfungi:YBR101C_mRNA(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006417"(regulation of translation)|go:"GO:0071629"(cytoplasm protein quality control by the ubiquitin-proteasome system)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013918(Nucleotide exchange factor Fes1)|interpro:IPR016024(Armadillo-type fold)|sgd:YBR101C(identity)	-	-	crc64:4A50D069625BA500	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:0I+wYut3naJRzzgmMSax/1mZZwA9606	rogid:swXhGbIfsVTGs+eOqqViPwySpI0559292	intact-crc:4F73E41ECBFE6A0A|rigid:wjVULKBxWaRB64mV9VWXcOKdgDU	false	sufficient binding region:61-646	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O95273	uniprotkb:P38260	intact:EBI-748961|uniprotkb:A8K3Q0|uniprotkb:A8K3U2|uniprotkb:Q6ZQN9|uniprotkb:Q7Z519|uniprotkb:Q8NBS7|uniprotkb:Q8NBY2|uniprotkb:Q9NS19|uniprotkb:Q9NYH3|uniprotkb:Q9UHX9|ensembl:ENSP00000300213	intact:EBI-21563|uniprotkb:D6VQA0|ensemblfungi:YBR101C	psi-mi:ccdb1_human(display_long)|uniprotkb:Grap2 and cyclin-D-interacting protein(gene name synonym)|uniprotkb:Human homolog of Maid(gene name synonym)|uniprotkb:CCNDBP1(gene name)|psi-mi:CCNDBP1(display_short)|uniprotkb:DIP1(gene name synonym)|uniprotkb:GCIP(gene name synonym)|uniprotkb:HHM(gene name synonym)	psi-mi:fes1_yeast(display_long)|uniprotkb:YBR101C(locus name)|uniprotkb:YBR0830(orf name)|uniprotkb:Factor exchange for SSA1 protein 1(gene name synonym)|uniprotkb:FES1(gene name)|psi-mi:FES1(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11557198|imex:IM-24995-4597	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_036274.3|ensembl:ENSG00000166946(gene)|ensembl:ENST00000300213(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0016604"(nuclear body)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR026907|mint:O95273|rcsb pdb:3AY5|entrezgene/locuslink:23582(identity)	sgd:S000000305|refseq:NP_009659.3|mint:P38260|dip:DIP-4918N|ensemblfungi:YBR101C(gene)|ensemblfungi:YBR101C_mRNA(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006417"(regulation of translation)|go:"GO:0071629"(cytoplasm protein quality control by the ubiquitin-proteasome system)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013918(Nucleotide exchange factor Fes1)|interpro:IPR016024(Armadillo-type fold)|sgd:YBR101C(identity)	-	-	crc64:4A50D069625BA500	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Vi9aoFc+Mov6P3X6KGmsTxXqxvM9606	rogid:swXhGbIfsVTGs+eOqqViPwySpI0559292	intact-crc:8AFDF4EC34E8AAF5|rigid:oUDMwT/PEowBr+fIUoVzUYlKGIY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P56279	uniprotkb:P38251	intact:EBI-749995|uniprotkb:Q6IBK7|ensembl:ENSP00000385036|ensembl:ENSP00000450496|ensembl:ENSP00000450701|ensembl:ENSP00000451506	intact:EBI-15016|uniprotkb:D6VQ88|ensemblfungi:YBR087W	psi-mi:tcl1a_human(display_long)|uniprotkb:Protein p14 TCL1(gene name synonym)|uniprotkb:Oncogene TCL-1(gene name synonym)|uniprotkb:TCL1A(gene name)|psi-mi:TCL1A(display_short)|uniprotkb:TCL1(gene name synonym)	psi-mi:rfc5_yeast(display_long)|uniprotkb:RFC5(gene name)|psi-mi:RFC5(display_short)|uniprotkb:YBR087W(locus name)|uniprotkb:YBR0810(orf name)|uniprotkb:Activator 1 40 kDa subunit(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11557189|imex:IM-24995-4596	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001092195.1|refseq:NP_068801.1|refseq:XP_016877165.1|refseq:XP_016877166.1|dip:DIP-60787N|ensembl:ENSG00000100721(gene)|ensembl:ENST00000402399(transcript)|ensembl:ENST00000554012(transcript)|ensembl:ENST00000555202(transcript)|ensembl:ENST00000556450(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010918"(positive regulation of mitochondrial membrane potential)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|interpro:IPR004832(TCL1/MTCP1)|interpro:IPR036672|rcsb pdb:1JSG|entrezgene/locuslink:8115(identity)	sgd:S000000291|refseq:NP_009644.3|go:"GO:0005634"(nucleus)|go:"GO:0005663"(DNA replication factor C complex)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006272"(leading strand elongation)|go:"GO:0006281"(DNA repair)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0031389"(Rad17 RFC-like complex)|go:"GO:0031390"(Ctf18 RFC-like complex)|go:"GO:0031391"(Elg1 RFC-like complex)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR027417|rcsb pdb:1SXJ|reactome:R-SCE-110312|reactome:R-SCE-110320|reactome:R-SCE-176187|reactome:R-SCE-5655862|reactome:R-SCE-5656121|reactome:R-SCE-5656169|reactome:R-SCE-5696397|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-69091|go:"GO:0005524"(ATP binding)|ensemblfungi:YBR087W(gene)|ensemblfungi:YBR087W_mRNA(transcript)|go:"GO:0003677"(DNA binding)|dip:DIP-2531N|mint:P38251|sgd:YBR087W(identity)	-	-	crc64:4CD403AF2AFA2961	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:c3GIYkYNb+wWlxn59oU2vpvbfhI9606	rogid:+ZnpxdiC5XBOQaSnExK98LVvFvA559292	intact-crc:28F940C05F581AD4|rigid:LA6kcR6908IRGzzUl0yjuxi7oxQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38247	uniprotkb:Q9UNE7	intact:EBI-21507|uniprotkb:D6VQ76|ensemblfungi:YBR077C	intact:EBI-357085|uniprotkb:O60526|uniprotkb:Q969U2|uniprotkb:Q9HBT1|uniprotkb:A2IDB9|ensembl:ENSP00000219548	psi-mi:slm4_yeast(display_long)|uniprotkb:YBR077C(locus name)|uniprotkb:YBR0723(orf name)|uniprotkb:GSE complex subunit 1(gene name synonym)|uniprotkb:EGO complex subunit 3(gene name synonym)|uniprotkb:SLM4(gene name)|psi-mi:SLM4(display_short)|uniprotkb:EGO3(gene name synonym)|uniprotkb:GSE1(gene name synonym)	psi-mi:chip_human(display_long)|uniprotkb:CHIP(gene name synonym)|uniprotkb:STUB1(gene name)|psi-mi:STUB1(display_short)|uniprotkb:PP1131(orf name)|uniprotkb:Carboxy terminus of Hsp70-interacting protein(gene name synonym)|uniprotkb:STIP1 homology and U box-containing protein 1(gene name synonym)|uniprotkb:CLL-associated antigen KW-8(gene name synonym)|uniprotkb:Antigen NY-CO-7(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase CHIP(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11557180|imex:IM-24995-4595	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009633.3|sgd:S000000281|mint:P38247|dip:DIP-1763N|ensemblfungi:YBR077C(gene)|ensemblfungi:YBR077C_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0007165"(signal transduction)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016237"(lysosomal microautophagy)|go:"GO:0031902"(late endosome membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0071986"(Ragulator complex)|interpro:IPR020233|rcsb pdb:3LGO|rcsb pdb:4FTX|rcsb pdb:4FUW|rcsb pdb:4XPM|rcsb pdb:6JWP|sgd:YBR077C(identity)	dip:DIP-29752N|refseq:NP_005852.2|refseq:NP_001280126.1|ensembl:ENSG00000103266(gene)|ensembl:ENST00000219548(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0002931"(response to ischemia)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030911"(TPR domain binding)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031371"(ubiquitin conjugating enzyme complex)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031943"(regulation of glucocorticoid metabolic process)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|go:"GO:0034605"(cellular response to heat)|go:"GO:0038128"(ERBB2 signaling pathway)|go:"GO:0042405"(nuclear inclusion body)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0046332"(SMAD binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0051604"(protein maturation)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0030579"(ubiquitin-dependent SMAD protein catabolic process)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061684"(chaperone-mediated autophagy)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0071218"(cellular response to misfolded protein)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0090035"(positive regulation of chaperone-mediated protein complex assembly)|go:"GO:0101031"(chaperone complex)|interpro:IPR003613(U box)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019734|interpro:IPR041312|mint:Q9UNE7|rcsb pdb:4KBQ|rcsb pdb:6EFK|rcsb pdb:6NSV|reactome:R-HSA-2173788|reactome:R-HSA-5213460|reactome:R-HSA-5675482|reactome:R-HSA-8863795|reactome:R-HSA-8939902|reactome:R-HSA-8948751|reactome:R-HSA-983168|entrezgene/locuslink:10273(identity)	-	crc64:D64ABDE1CDF265FD	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:BCEWjA3PQvwm3n08QwY0D//TpbA559292	rogid:h4QyIM0TptgkQppPUgiKn68XjP49606	intact-crc:EC3B2183BC395171|rigid:iLCs6fLjNe3KPIp16E3mT4+dQwM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8N5R6	uniprotkb:P38234	intact:EBI-740841|intact:EBI-953781|uniprotkb:B3KQ49|uniprotkb:A8K3U4|uniprotkb:A8MPQ6|uniprotkb:A8MV61|uniprotkb:A8MVU9|uniprotkb:Q9H5Q6|uniprotkb:Q8TAX6|intact:EBI-2320546|intact:EBI-11522976	intact:EBI-21445|uniprotkb:D6VQ51|ensemblfungi:YBR052C	psi-mi:ccd33_human(display_long)|uniprotkb:CCDC33(gene name)|psi-mi:CCDC33(display_short)|uniprotkb:Cancer/testis antigen 61(gene name synonym)	psi-mi:rfs1_yeast(display_long)|uniprotkb:YBR052C(locus name)|uniprotkb:YBR0505(orf name)|uniprotkb:RFS1(gene name)|psi-mi:RFS1(display_short)|uniprotkb:RAD55 suppressor protein 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11557171|imex:IM-24995-4594	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_079331.3|interpro:IPR000008(C2 calcium-dependent membrane targeting)|go:"GO:0005777"(peroxisome)|refseq:NP_001274110.1|refseq:NP_877592.2|mint:Q8N5R6|interpro:IPR035892|interpro:IPR039889|entrezgene/locuslink:80125(identity)	refseq:NP_009608.1|sgd:S000000256|mint:P38234|dip:DIP-1761N|ensemblfungi:YBR052C(gene)|ensemblfungi:YBR052C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0010181"(FMN binding)|go:"GO:0045121"(membrane raft)|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|interpro:IPR029039|sgd:YBR052C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2021/11/30	rogid:eEIn7pQyfdHWx8TeLJpYy0i/gww9606	rogid:cb04D8hoVh5fvWEd5oT6iDTL2X0559292	intact-crc:8D1D2068C0B27CF5|rigid:IRoMaPKSynRAVuLRVfQGYPuTB3o	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38263	uniprotkb:Q15654	intact:EBI-20304|uniprotkb:D6VQA4|ensemblfungi:YBR105C	intact:EBI-742327|uniprotkb:O15170|uniprotkb:O15275|uniprotkb:Q9BTB2|uniprotkb:Q9BUE5|uniprotkb:Q9BXP3|uniprotkb:Q9UNT4|uniprotkb:A4D2E7|ensembl:ENSP00000200457|uniprotkb:F2ZC07|uniprotkb:F2ZC08	psi-mi:gid4_yeast(display_long)|uniprotkb:VID24(gene name)|psi-mi:VID24(display_short)|uniprotkb:YBR105C(locus name)|uniprotkb:YBR0834(orf name)|uniprotkb:GID4(gene name synonym)|uniprotkb:Glucose-induced degradation protein 4(gene name synonym)	psi-mi:trip6_human(display_long)|uniprotkb:TRIP6(gene name)|psi-mi:TRIP6(display_short)|uniprotkb:OIP1(gene name synonym)|uniprotkb:Opa-interacting protein 1(gene name synonym)|uniprotkb:Zyxin-related protein 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11557269|imex:IM-24995-4604	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009663.1|sgd:S000000309|ensemblfungi:YBR105C(gene)|ensemblfungi:YBR105C_mRNA(transcript)|go:"GO:0005773"(vacuole)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0007039"(protein catabolic process in the vacuole)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034657"(GID complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045721"(negative regulation of gluconeogenesis)|go:"GO:0071596"(ubiquitin-dependent protein catabolic process via the N-end rule pathway)|interpro:IPR018618|rcsb pdb:6SWY|dip:DIP-4502N|mint:P38263|sgd:YBR105C(identity)	refseq:NP_003293.2|ensembl:ENSP00000200457|ensembl:ENST00000417475|ensembl:ENSP00000413817|ensembl:ENST00000437505|ensembl:ENSP00000410736|ensembl:ENST00000619988|ensembl:ENSP00000479865|ensembl:ENSG00000087077(gene)|ensembl:ENST00000200457(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003723"(RNA binding)|go:"GO:0005149"(interleukin-1 receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0019900"(kinase binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0043009"(chordate embryonic development)|go:"GO:0046872"(metal ion binding)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|interpro:IPR001781(Zinc finger, LIM-type)|mint:Q15654|rcsb pdb:1X61|rcsb pdb:2DLO|dip:DIP-34466N|entrezgene/locuslink:7205(identity)	-	crc64:FF020B239676E0B2	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:ag6caXMIP/qIv27yJtSEmlBoI7g559292	rogid:9Okf3b6sMMwX5awAx991GN9iSsQ9606	intact-crc:7E234033500E585B|rigid:xb2A35dOA0wawIH6nclhVdXnXro	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38263	uniprotkb:P14373	intact:EBI-20304|uniprotkb:D6VQA4|ensemblfungi:YBR105C	intact:EBI-719493|uniprotkb:A2BE15|uniprotkb:Q5RJA8|uniprotkb:Q5ST26|uniprotkb:Q6LA73|uniprotkb:Q6NXR9|uniprotkb:Q9BZY6|uniprotkb:Q9UJL3|ensembl:ENSP00000383555|ensembl:ENSP00000392787|ensembl:ENSP00000405229|ensembl:ENSP00000414793|ensembl:ENSP00000366404	psi-mi:gid4_yeast(display_long)|uniprotkb:VID24(gene name)|psi-mi:VID24(display_short)|uniprotkb:YBR105C(locus name)|uniprotkb:YBR0834(orf name)|uniprotkb:GID4(gene name synonym)|uniprotkb:Glucose-induced degradation protein 4(gene name synonym)	psi-mi:tri27_human(display_long)|uniprotkb:TRIM27(gene name)|psi-mi:TRIM27(display_short)|uniprotkb:RNF76(gene name synonym)|uniprotkb:RFP(gene name synonym)|uniprotkb:Ret finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 27(gene name synonym)|uniprotkb:RING finger protein 76(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM27(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11557260|imex:IM-24995-4603	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009663.1|sgd:S000000309|ensemblfungi:YBR105C(gene)|ensemblfungi:YBR105C_mRNA(transcript)|go:"GO:0005773"(vacuole)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0007039"(protein catabolic process in the vacuole)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034657"(GID complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045721"(negative regulation of gluconeogenesis)|go:"GO:0071596"(ubiquitin-dependent protein catabolic process via the N-end rule pathway)|interpro:IPR018618|rcsb pdb:6SWY|dip:DIP-4502N|mint:P38263|sgd:YBR105C(identity)	refseq:NP_006501.1|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0090281"(negative regulation of calcium ion import)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR020457|interpro:IPR035791|interpro:IPR043136|mint:P14373|reactome:R-HSA-3232142|reactome:R-HSA-9635465|reactome:R-HSA-8948751|ensembl:ENSG00000204713(gene)|ensembl:ENSG00000215641(gene)|ensembl:ENSG00000229006(gene)|ensembl:ENSG00000234495(gene)|ensembl:ENSG00000237071(gene)|ensembl:ENST00000377199(transcript)|ensembl:ENST00000400720(transcript)|ensembl:ENST00000431123(transcript)|ensembl:ENST00000435528(transcript)|ensembl:ENST00000437160(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001650"(fibrillar center)|go:"GO:0002820"(negative regulation of adaptive immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|entrezgene/locuslink:5987(identity)	-	crc64:FF020B239676E0B2	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:ag6caXMIP/qIv27yJtSEmlBoI7g559292	rogid:dsfH5OUghD8KSaTz1SFw9OYVTK49606	intact-crc:D41DF545207D854E|rigid:Euv0GGsb1JA1Id2ofa27N81yVkI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38263	uniprotkb:Q08379	intact:EBI-20304|uniprotkb:D6VQA4|ensemblfungi:YBR105C	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	psi-mi:gid4_yeast(display_long)|uniprotkb:VID24(gene name)|psi-mi:VID24(display_short)|uniprotkb:YBR105C(locus name)|uniprotkb:YBR0834(orf name)|uniprotkb:GID4(gene name synonym)|uniprotkb:Glucose-induced degradation protein 4(gene name synonym)	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11557249|imex:IM-24995-4602	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009663.1|sgd:S000000309|ensemblfungi:YBR105C(gene)|ensemblfungi:YBR105C_mRNA(transcript)|go:"GO:0005773"(vacuole)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0007039"(protein catabolic process in the vacuole)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034657"(GID complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045721"(negative regulation of gluconeogenesis)|go:"GO:0071596"(ubiquitin-dependent protein catabolic process via the N-end rule pathway)|interpro:IPR018618|rcsb pdb:6SWY|dip:DIP-4502N|mint:P38263|sgd:YBR105C(identity)	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N|entrezgene/locuslink:2801(identity)	-	crc64:FF020B239676E0B2	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2017/05/26	rogid:ag6caXMIP/qIv27yJtSEmlBoI7g559292	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	intact-crc:85583E2C0A28B09D|rigid:tulP4I+Hi4CulghhzjhObGzAJfk	false	-	sufficient binding region:383-1002	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UKT9	uniprotkb:P38261	intact:EBI-747204|uniprotkb:Q8WWQ9|uniprotkb:Q8WWR0|uniprotkb:Q8WWR1|uniprotkb:Q8WWR2|uniprotkb:Q8WWR3|uniprotkb:Q8N574|uniprotkb:B4DVV5|uniprotkb:Q69BL6|uniprotkb:Q69BL7|uniprotkb:Q69BL8|uniprotkb:Q69BL9|uniprotkb:Q69BM0|uniprotkb:Q69BM1|uniprotkb:Q69BM2|uniprotkb:Q69BM3|uniprotkb:Q69BM5|ensembl:ENSP00000344544	intact:EBI-21567|uniprotkb:D6VQA1|ensemblfungi:YBR102C	psi-mi:ikzf3_human(display_long)|uniprotkb:ZNFN1A3(gene name synonym)|uniprotkb:Ikaros family zinc finger protein 3(gene name synonym)|uniprotkb:IKZF3(gene name)|psi-mi:IKZF3(display_short)	psi-mi:exo84_yeast(display_long)|uniprotkb:YBR102C(locus name)|uniprotkb:YBR0831(orf name)|uniprotkb:Exocyst complex protein of 84 kDa(gene name synonym)|uniprotkb:EXO84(gene name)|psi-mi:EXO84(display_short)|uniprotkb:USA3(gene name synonym)|uniprotkb:U1 SNP1-associating protein 3(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11557240|imex:IM-24995-4601	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001271443.1|refseq:NP_001271444.1|refseq:NP_036613.2|refseq:NP_899051.1|refseq:NP_899052.1|refseq:NP_899053.1|refseq:NP_899054.1|refseq:NP_899055.1|refseq:NP_001271445.1|refseq:NP_001244337.1|refseq:NP_001244338.1|refseq:NP_001244339.1|refseq:NP_001244340.1|refseq:NP_001244341.1|refseq:NP_001244342.1|refseq:NP_001244343.1|ensembl:ENSG00000161405(gene)|ensembl:ENST00000346872(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007498"(mesoderm development)|go:"GO:0009617"(response to bacterium)|go:"GO:0030888"(regulation of B cell proliferation)|go:"GO:0042113"(B cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045577"(regulation of B cell differentiation)|go:"GO:0045619"(regulation of lymphocyte differentiation)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|go:"GO:0046872"(metal ion binding)|dip:DIP-56975N|entrezgene/locuslink:22806(identity)	refseq:NP_009660.1|sgd:S000000306|mint:P38261|dip:DIP-2732N|ensemblfungi:YBR102C(gene)|ensemblfungi:YBR102C_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0000145"(exocyst)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0001927"(exocyst assembly)|go:"GO:0005628"(prospore membrane)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0008104"(protein localization)|go:"GO:0015031"(protein transport)|go:"GO:0030133"(transport vesicle)|go:"GO:0043332"(mating projection tip)|go:"GO:0051601"(exocyst localization)|go:"GO:0090522"(vesicle tethering involved in exocytosis)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR032403|interpro:IPR033961|interpro:IPR042560|interpro:IPR042561|rcsb pdb:2D2S|rcsb pdb:5YFP|rcsb pdb:6VKL|reactome:R-SCE-264876|sgd:YBR102C(identity)	-	-	crc64:1BCDE834466C3536	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:2Kp6LefSLfK5VIiE6DmQusFIfMY9606	rogid:tJ29//zd8m0QGJu94oH597pBVTg559292	intact-crc:ECF4D0101CF79285|rigid:vWYb+BjNTJ6s0RM+v9zw/HiC52w	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38261	uniprotkb:Q08379	intact:EBI-21567|uniprotkb:D6VQA1|ensemblfungi:YBR102C	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	psi-mi:exo84_yeast(display_long)|uniprotkb:YBR102C(locus name)|uniprotkb:YBR0831(orf name)|uniprotkb:Exocyst complex protein of 84 kDa(gene name synonym)|uniprotkb:EXO84(gene name)|psi-mi:EXO84(display_short)|uniprotkb:USA3(gene name synonym)|uniprotkb:U1 SNP1-associating protein 3(gene name synonym)	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11557229|imex:IM-24995-4600	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009660.1|sgd:S000000306|mint:P38261|dip:DIP-2732N|ensemblfungi:YBR102C(gene)|ensemblfungi:YBR102C_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0000145"(exocyst)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0001927"(exocyst assembly)|go:"GO:0005628"(prospore membrane)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0008104"(protein localization)|go:"GO:0015031"(protein transport)|go:"GO:0030133"(transport vesicle)|go:"GO:0043332"(mating projection tip)|go:"GO:0051601"(exocyst localization)|go:"GO:0090522"(vesicle tethering involved in exocytosis)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR032403|interpro:IPR033961|interpro:IPR042560|interpro:IPR042561|rcsb pdb:2D2S|rcsb pdb:5YFP|rcsb pdb:6VKL|reactome:R-SCE-264876|sgd:YBR102C(identity)	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N|entrezgene/locuslink:2801(identity)	-	crc64:1BCDE834466C3536	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2017/05/26	rogid:tJ29//zd8m0QGJu94oH597pBVTg559292	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	intact-crc:81C97B5A44F51233|rigid:CwIf3wQ9preYNggEHdldYdCDy/w	false	-	sufficient binding region:383-1002	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UI14	uniprotkb:P38295	intact:EBI-712367|ensembl:ENSP00000222008|uniprotkb:Q7Z4Y2|uniprotkb:Q9Y3R1	intact:EBI-20890|uniprotkb:D6VQH2|ensemblfungi:YBR177C	psi-mi:praf1_human(display_long)|uniprotkb:PRA1 family protein 1(gene name synonym)|uniprotkb:RABAC1(gene name)|psi-mi:RABAC1(display_short)|uniprotkb:PRA1(gene name synonym)|uniprotkb:PRAF1(gene name synonym)	psi-mi:mcfs2_yeast(display_long)|uniprotkb:YBR177C(locus name)|uniprotkb:YBR1239(orf name)|uniprotkb:EHT1(gene name)|psi-mi:EHT1(display_short)|uniprotkb:Alcohol O-acetyltransferase(gene name synonym)|uniprotkb:Ethanol hexanoyl transferase 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11557327|imex:IM-24995-4610	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006414.2|ensembl:ENSG00000105404(gene)|ensembl:ENST00000222008(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0070064"(proline-rich region binding)|interpro:IPR004895(Prenylated rab acceptor PRA1)|mint:Q9UI14|entrezgene/locuslink:10567(identity)	refseq:NP_009736.3|sgd:S000000381|interpro:IPR012020(AB-hydrolase YheT, putative)|interpro:IPR000073(Alpha/beta hydrolase fold-1)|interpro:IPR000952(Protein of unknown function UPF0017, hydrolase-like, conserved site)|mint:P38295|interpro:IPR029058|ensemblfungi:YBR177C(gene)|ensemblfungi:YBR177C_mRNA(transcript)|go:"GO:0004026"(alcohol O-acetyltransferase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0008126"(acetylesterase activity)|go:"GO:0017171"(serine hydrolase activity)|go:"GO:0034319"(alcohol O-butanoyltransferase activity)|go:"GO:0034338"(short-chain carboxylesterase activity)|go:"GO:0044255"(cellular lipid metabolic process)|go:"GO:0047372"(acylglycerol lipase activity)|go:"GO:0051792"(medium-chain fatty acid biosynthetic process)|go:"GO:0051793"(medium-chain fatty acid catabolic process)|reactome:R-SCE-1483191|sgd:YBR177C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:WS2rUY7yXRbR7pqWgfUCbnEiDbg9606	rogid:9arzlcrZmkK0VXN7Zw87dAe1Txc559292	intact-crc:6D44B2313E2F35C0|rigid:PLLUrVsNaFuk2Qvs8fALPfUfHE4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96LP2	uniprotkb:P38271	intact:EBI-10290827|ensembl:ENSP00000283357	intact:EBI-12563|uniprotkb:D6VQC6|ensemblfungi:YBR129C	psi-mi:fa81b_human(display_long)|uniprotkb:FAM81B(gene name)|psi-mi:FAM81B(display_short)	psi-mi:opy1_yeast(display_long)|uniprotkb:OPY1(gene name)|psi-mi:OPY1(display_short)|uniprotkb:YBR129C(locus name)|uniprotkb:YBR1004(orf name)|uniprotkb:Overproduction-induced pheromone-resistant yeast protein 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11557316|imex:IM-24995-4609	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_689761.2|ensembl:ENSG00000153347(gene)|ensembl:ENST00000283357(transcript)|go:"GO:0005634"(nucleus)|interpro:IPR029619|interpro:IPR029620|entrezgene/locuslink:153643(identity)	ensemblfungi:YBR129C(gene)|ensemblfungi:YBR129C_mRNA(transcript)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:1902647"(negative regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016609(Uncharacterised conserved protein UCP013217, Opy1p)|refseq:NP_009687.1|sgd:S000000333|dip:DIP-4768N|sgd:YBR129C(identity)	-	-	crc64:BB4BECCA7C67A5D9	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2020/03/03	rogid:V9VtnYUHk767ZnWUCuuxiUfJF+09606	rogid:97mFgMzTXaBI8NoMtAweXDE8i3s559292	intact-crc:9B170FDF95D690C4|rigid:n0Yhpn+39w5sOOefaMKMeX8eiVc	false	sufficient binding region:39-452	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P14136	uniprotkb:P38265	intact:EBI-744302|uniprotkb:Q53H98|uniprotkb:Q5D055|uniprotkb:Q6ZQS3|uniprotkb:Q7Z5J6|uniprotkb:Q7Z5J7|uniprotkb:Q96KS4|uniprotkb:Q96P18|uniprotkb:Q9UFD0|uniprotkb:B2RD44|uniprotkb:D3DX59|intact:EBI-3909365|uniprotkb:E9PAX3|ensembl:ENSP00000466598|uniprotkb:A7REI1	intact:EBI-21579|uniprotkb:D6VQA6|ensemblfungi:YBR107C	psi-mi:gfap_human(display_long)|uniprotkb:GFAP(gene name)|psi-mi:GFAP(display_short)	psi-mi:cenpl_yeast(display_long)|uniprotkb:YBR107C(locus name)|uniprotkb:YBR0836(orf name)|uniprotkb:Increased minichromosome loss protein 3(gene name synonym)|uniprotkb:Minichromosome maintenance protein 19(gene name synonym)|uniprotkb:IML3(gene name)|psi-mi:IML3(display_short)|uniprotkb:MCM19(gene name synonym)|uniprotkb:CENP-L homolog(gene name synonym)|uniprotkb:Constitutive centromere-associated network protein IML3(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11557307|imex:IM-24995-4608	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001124491.1|refseq:NP_001229305.1|refseq:NP_002046.1|ensembl:ENSG00000131095(gene)|ensembl:ENST00000588735(transcript)|go:"GO:0005178"(integrin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0009611"(response to wounding)|go:"GO:0010467"(gene expression)|go:"GO:0010625"(positive regulation of Schwann cell proliferation)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0014002"(astrocyte development)|go:"GO:0019900"(kinase binding)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0031102"(neuron projection regeneration)|go:"GO:0042802"(identical protein binding)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0044297"(cell body)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0051580"(regulation of neurotransmitter uptake)|go:"GO:0060020"(Bergmann glial cell differentiation)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0070779"(D-aspartate import across plasma membrane)|go:"GO:0097450"(astrocyte end-foot)|go:"GO:0098574"(cytoplasmic side of lysosomal membrane)|go:"GO:1904714"(regulation of chaperone-mediated autophagy)|interpro:IPR006821(Intermediate filament, DNA-binding region)|interpro:IPR018039|interpro:IPR027701|interpro:IPR039008|mint:P14136|rcsb pdb:6A9P|reactome:R-HSA-1251985|reactome:R-HSA-9613829|entrezgene/locuslink:2670(identity)	sgd:S000000311|refseq:NP_009665.3|mint:P38265|dip:DIP-5360N|ensemblfungi:YBR107C(gene)|ensemblfungi:YBR107C_mRNA(transcript)|go:"GO:0000940"(outer kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0030437"(ascospore formation)|go:"GO:0034087"(establishment of mitotic sister chromatid cohesion)|go:"GO:0034089"(establishment of meiotic sister chromatid cohesion)|go:"GO:0034090"(maintenance of meiotic sister chromatid cohesion)|go:"GO:0045144"(meiotic sister chromatid segregation)|go:"GO:0051301"(cell division)|go:"GO:0071459"(protein localization to chromosome, centromeric region)|rcsb pdb:4IT3|rcsb pdb:4JE3|rcsb pdb:4KR1|rcsb pdb:6NUW|rcsb pdb:6QLD|rcsb pdb:6QLE|rcsb pdb:6QLF|sgd:YBR107C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Pz4JW0WjMjBYILTDSX9jUmMqWhg9606	rogid:Wq132ybN9X9ZoP+Z9KcTTvkz2t4559292	intact-crc:30FBD153A581F582|rigid:hWeq1Mm67dM5sUZLU4tMzDOgmUA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38263	uniprotkb:Q9UKT9	intact:EBI-20304|uniprotkb:D6VQA4|ensemblfungi:YBR105C	intact:EBI-747204|uniprotkb:Q8WWQ9|uniprotkb:Q8WWR0|uniprotkb:Q8WWR1|uniprotkb:Q8WWR2|uniprotkb:Q8WWR3|uniprotkb:Q8N574|uniprotkb:B4DVV5|uniprotkb:Q69BL6|uniprotkb:Q69BL7|uniprotkb:Q69BL8|uniprotkb:Q69BL9|uniprotkb:Q69BM0|uniprotkb:Q69BM1|uniprotkb:Q69BM2|uniprotkb:Q69BM3|uniprotkb:Q69BM5|ensembl:ENSP00000344544	psi-mi:gid4_yeast(display_long)|uniprotkb:VID24(gene name)|psi-mi:VID24(display_short)|uniprotkb:YBR105C(locus name)|uniprotkb:YBR0834(orf name)|uniprotkb:GID4(gene name synonym)|uniprotkb:Glucose-induced degradation protein 4(gene name synonym)	psi-mi:ikzf3_human(display_long)|uniprotkb:ZNFN1A3(gene name synonym)|uniprotkb:Ikaros family zinc finger protein 3(gene name synonym)|uniprotkb:IKZF3(gene name)|psi-mi:IKZF3(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11557298|imex:IM-24995-4607	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009663.1|sgd:S000000309|ensemblfungi:YBR105C(gene)|ensemblfungi:YBR105C_mRNA(transcript)|go:"GO:0005773"(vacuole)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0007039"(protein catabolic process in the vacuole)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034657"(GID complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045721"(negative regulation of gluconeogenesis)|go:"GO:0071596"(ubiquitin-dependent protein catabolic process via the N-end rule pathway)|interpro:IPR018618|rcsb pdb:6SWY|dip:DIP-4502N|mint:P38263|sgd:YBR105C(identity)	refseq:NP_001271443.1|refseq:NP_001271444.1|refseq:NP_036613.2|refseq:NP_899051.1|refseq:NP_899052.1|refseq:NP_899053.1|refseq:NP_899054.1|refseq:NP_899055.1|refseq:NP_001271445.1|refseq:NP_001244337.1|refseq:NP_001244338.1|refseq:NP_001244339.1|refseq:NP_001244340.1|refseq:NP_001244341.1|refseq:NP_001244342.1|refseq:NP_001244343.1|ensembl:ENSG00000161405(gene)|ensembl:ENST00000346872(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007498"(mesoderm development)|go:"GO:0009617"(response to bacterium)|go:"GO:0030888"(regulation of B cell proliferation)|go:"GO:0042113"(B cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045577"(regulation of B cell differentiation)|go:"GO:0045619"(regulation of lymphocyte differentiation)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|go:"GO:0046872"(metal ion binding)|dip:DIP-56975N|entrezgene/locuslink:22806(identity)	-	crc64:FF020B239676E0B2	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:ag6caXMIP/qIv27yJtSEmlBoI7g559292	rogid:2Kp6LefSLfK5VIiE6DmQusFIfMY9606	intact-crc:86A44EF838C18BE6|rigid:cTZ1r5urqYii2IhNTMEvDSPo/oQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38263	uniprotkb:Q8TAP6	intact:EBI-20304|uniprotkb:D6VQA4|ensemblfungi:YBR105C	intact:EBI-742887|ensembl:ENSP00000262127|uniprotkb:Q658N5|uniprotkb:Q9H9U7|uniprotkb:B0YJB2|uniprotkb:B4DXG5|uniprotkb:B4DZW1	psi-mi:gid4_yeast(display_long)|uniprotkb:VID24(gene name)|psi-mi:VID24(display_short)|uniprotkb:YBR105C(locus name)|uniprotkb:YBR0834(orf name)|uniprotkb:GID4(gene name synonym)|uniprotkb:Glucose-induced degradation protein 4(gene name synonym)	psi-mi:cep76_human(display_long)|uniprotkb:CEP76(gene name)|psi-mi:CEP76(display_short)|uniprotkb:C18orf9(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11557289|imex:IM-24995-4606	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009663.1|sgd:S000000309|ensemblfungi:YBR105C(gene)|ensemblfungi:YBR105C_mRNA(transcript)|go:"GO:0005773"(vacuole)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0007039"(protein catabolic process in the vacuole)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034657"(GID complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045721"(negative regulation of gluconeogenesis)|go:"GO:0071596"(ubiquitin-dependent protein catabolic process via the N-end rule pathway)|interpro:IPR018618|rcsb pdb:6SWY|dip:DIP-4502N|mint:P38263|sgd:YBR105C(identity)	refseq:NP_079175.2|ensembl:ENSG00000101624(gene)|ensembl:ENST00000262127(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0046599"(regulation of centriole replication)|interpro:IPR028926|interpro:IPR038765|mint:Q8TAP6|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_001258918.1|entrezgene/locuslink:79959(identity)	-	crc64:FF020B239676E0B2	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:ag6caXMIP/qIv27yJtSEmlBoI7g559292	rogid:fWzb8oIU35oVWomyDrf8u5sbxUk9606	intact-crc:1CFB50EB8C5F41FA|rigid:ZDC0HXWv5sC1tHgjF4wrRkR6x2Q	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q5SW96	uniprotkb:P38263	intact:EBI-747813|uniprotkb:A2BHI5|uniprotkb:Q6TQS9|uniprotkb:Q8N2Y0|uniprotkb:Q9UFI9|intact:EBI-28971912|ensembl:ENSP00000363458	intact:EBI-20304|uniprotkb:D6VQA4|ensemblfungi:YBR105C	psi-mi:arh_human(display_long)|uniprotkb:Autosomal recessive hypercholesterolemia protein(gene name synonym)|uniprotkb:LDLRAP1(gene name)|psi-mi:LDLRAP1(display_short)|uniprotkb:ARH(gene name synonym)	psi-mi:gid4_yeast(display_long)|uniprotkb:VID24(gene name)|psi-mi:VID24(display_short)|uniprotkb:YBR105C(locus name)|uniprotkb:YBR0834(orf name)|uniprotkb:GID4(gene name synonym)|uniprotkb:Glucose-induced degradation protein 4(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11557278|imex:IM-24995-4605	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000363458|refseq:NP_056442.2|go:"GO:0042982"(amyloid precursor protein metabolic process)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0055037"(recycling endosome)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0090118"(receptor-mediated endocytosis involved in cholesterol transport)|go:"GO:0090205"(positive regulation of cholesterol metabolic process)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905581"(positive regulation of low-density lipoprotein particle clearance)|go:"GO:1905602"(positive regulation of receptor-mediated endocytosis involved in cholesterol transport)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|rcsb pdb:2G30|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8964026|reactome:R-HSA-8964038|ensembl:ENSG00000157978(gene)|ensembl:ENST00000374338(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005883"(neurofilament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030276"(clathrin binding)|go:"GO:0030301"(cholesterol transport)|go:"GO:0030424"(axon)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031623"(receptor internalization)|go:"GO:0034383"(low-density lipoprotein particle clearance)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0035612"(AP-2 adaptor complex binding)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0035650"(AP-1 adaptor complex binding)|go:"GO:0042632"(cholesterol homeostasis)|entrezgene/locuslink:26119(identity)	refseq:NP_009663.1|sgd:S000000309|ensemblfungi:YBR105C(gene)|ensemblfungi:YBR105C_mRNA(transcript)|go:"GO:0005773"(vacuole)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0007039"(protein catabolic process in the vacuole)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034657"(GID complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045721"(negative regulation of gluconeogenesis)|go:"GO:0071596"(ubiquitin-dependent protein catabolic process via the N-end rule pathway)|interpro:IPR018618|rcsb pdb:6SWY|dip:DIP-4502N|mint:P38263|sgd:YBR105C(identity)	-	-	crc64:FF020B239676E0B2	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:dtBWLcVpVD/R0aKQZr9Nucfa1oo9606	rogid:ag6caXMIP/qIv27yJtSEmlBoI7g559292	intact-crc:303B23AF06DB3F30|rigid:fXQk8T6iq+9VLa3t8eummQvUx0o	false	sufficient binding region:46-308	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38334	uniprotkb:O43617	intact:EBI-19468|uniprotkb:D6VQQ0|ensemblfungi:YBR254C	intact:EBI-743566|uniprotkb:B2RDN2|uniprotkb:D3DPS2|uniprotkb:A6NDN0|ensembl:ENSP00000362261	psi-mi:trs20_yeast(display_long)|uniprotkb:TRS20(gene name)|psi-mi:TRS20(display_short)|uniprotkb:YBR254C(locus name)|uniprotkb:YBR1722(orf name)|uniprotkb:Transport protein particle 20 kDa subunit(gene name synonym)	psi-mi:tppc3_human(display_long)|uniprotkb:BET3 homolog(gene name synonym)|uniprotkb:TRAPPC3(gene name)|psi-mi:TRAPPC3(display_short)|uniprotkb:BET3(gene name synonym)|uniprotkb:CDABP0066(orf name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11557381|imex:IM-24995-4616	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009813.1|sgd:S000000458|ensemblfungi:YBR254C(gene)|ensemblfungi:YBR254C_mRNA(transcript)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006914"(autophagy)|go:"GO:0030008"(TRAPP complex)|go:"GO:0034622"|go:"GO:1990070"(TRAPPI protein complex)|go:"GO:1990071"(TRAPPII protein complex)|go:"GO:1990072"(TRAPPIII protein complex)|interpro:IPR006722(Sedlin)|interpro:IPR011012(Longin-like)|rcsb pdb:7KMT|reactome:R-SCE-204005|reactome:R-SCE-8876198|dip:DIP-1711N|mint:P38334|sgd:YBR254C(identity)	refseq:NP_055223.1|refseq:NP_001257823.1|refseq:NP_001257824.1|refseq:NP_001257825.1|refseq:NP_001257826.1|ensembl:ENSG00000054116(gene)|ensembl:ENST00000373166(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0030008"(TRAPP complex)|go:"GO:0033106"(cis-Golgi network membrane)|interpro:IPR007194("Transport protein particle (TRAPP) component, Bet3")|interpro:IPR016721(TRAPP I complex, Bet3)|interpro:IPR024096|mint:O43617|rcsb pdb:1SZ7|rcsb pdb:2C0J|rcsb pdb:2CFH|rcsb pdb:3KXC|reactome:R-HSA-204005|reactome:R-HSA-8876198|dip:DIP-47627N|entrezgene/locuslink:27095(identity)	-	crc64:82285CAEAC2735D9	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:RaZlF+nwUS/H7Sprxgo1jQ38V+8559292	rogid:YEQWfs0KIBIDkvJ+2Xtz8afsDCc9606	intact-crc:E7152CF53B09BC56|rigid:UVDmTrFMJBfUf4/fBI8TwZplmlE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96HH9	uniprotkb:P38331	intact:EBI-2832937|uniprotkb:Q9H753|uniprotkb:D3DSZ3|uniprotkb:B7Z1F2|uniprotkb:B7Z3R1|uniprotkb:B7Z6D8|uniprotkb:B7Z8T2|ensembl:ENSP00000285689	intact:EBI-21083|uniprotkb:D6VQN8|ensemblfungi:YBR242W	psi-mi:grm2b_human(display_long)|uniprotkb:GRAMD2B(gene name)|psi-mi:GRAMD2B(display_short)|uniprotkb:GRAMD3(gene name synonym)|uniprotkb:HCV NS3-transactivated protein 2(gene name synonym)|uniprotkb:NS3TP2(gene name synonym)	psi-mi:yb92_yeast(display_long)|uniprotkb:YBR1627(orf name)|uniprotkb:YBR242W(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11557372|imex:IM-24995-4615	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_016865274.1|refseq:NP_001139791.1|refseq:NP_001139792.1|refseq:NP_001139793.1|refseq:NP_001139794.1|refseq:NP_076416.2|refseq:XP_005272120.1|ensembl:ENSG00000155324(gene)|ensembl:ENST00000285689(transcript)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0042802"(identical protein binding)|interpro:IPR004182(GRAM)|interpro:IPR011993(Pleckstrin homology-type)|entrezgene/locuslink:65983(identity)	refseq:NP_009801.1|sgd:S000000446|dip:DIP-4887N|ensemblfungi:YBR242W(gene)|ensemblfungi:YBR242W_mRNA(transcript)|go:"GO:0002953"(5'-deoxynucleotidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009159"(deoxyribonucleoside monophosphate catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0050484"(GMP 5'-nucleotidase activity)|interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|interpro:IPR039356|sgd:YBR242W(identity)	-	-	crc64:CDE8283134B6F48F	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:6UkVJddV5/mHpLX/rk00jMwCA+k9606	rogid:YD0aYpVRCD7mMD3RTxVDksZoE1Q559292	intact-crc:CD98032BB9BC7045|rigid:ss4LaWn4LwpKJo9z82Mte3KQUTQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P63279	uniprotkb:P38319	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	intact:EBI-20997|uniprotkb:D6VQM0|ensemblfungi:YBR223C	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:tydp1_yeast(display_long)|uniprotkb:TDP1(gene name)|psi-mi:TDP1(display_short)|uniprotkb:YBR1520(orf name)|uniprotkb:YBR223C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11557363|imex:IM-24995-4614	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N|entrezgene/locuslink:7329(identity)	sgd:S000000427|refseq:NP_009782.3|mint:P38319|dip:DIP-4945N|rcsb pdb:3SQ3|rcsb pdb:3SQ5|rcsb pdb:3SQ7|rcsb pdb:3SQ8|ensemblfungi:YBR223C(gene)|ensemblfungi:YBR223C_mRNA(transcript)|go:"GO:0000012"(single strand break repair)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0004527"(exonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006281"(DNA repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0017005"(3'-tyrosyl-DNA phosphodiesterase activity)|go:"GO:0070260"(5'-tyrosyl-DNA phosphodiesterase activity)|interpro:IPR010347(Tyrosyl-DNA phosphodiesterase)|rcsb pdb:1Q32|sgd:YBR223C(identity)	-	-	crc64:E84C6685312DEC3F	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	rogid:VQHWWxxN+ijh3tjTmmwaPiIfGnU559292	intact-crc:3C0FFFBE3D9D7862|rigid:z8t5VknMUNe0ysJOGV5SKuS8VNY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38306	uniprotkb:Q9BW62	intact:EBI-20943|uniprotkb:D6VQJ3|ensemblfungi:YBR197C	intact:EBI-743591|uniprotkb:A8K5X4|ensembl:ENSP00000369989|ensembl:ENSP00000369991	psi-mi:yb47_yeast(display_long)|uniprotkb:YBR1409(orf name)|uniprotkb:YBR197C(locus name)	psi-mi:katl1_human(display_long)|uniprotkb:p60 katanin-like 1(gene name synonym)|uniprotkb:KATNAL1(gene name)|psi-mi:KATNAL1(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11557354|imex:IM-24995-4613	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000000401|refseq:NP_009756.1|mint:P38306|dip:DIP-4258N|ensemblfungi:YBR197C(gene)|ensemblfungi:YBR197C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|sgd:YBR197C(identity)	refseq:NP_001014402.1|refseq:NP_115492.1|refseq:XP_005266631.1|ensembl:ENSG00000102781(gene)|ensembl:ENST00000380615(transcript)|ensembl:ENST00000380617(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005874"(microtubule)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008017"(microtubule binding)|go:"GO:0008568"(microtubule-severing ATPase activity)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016853"(isomerase activity)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0042802"(identical protein binding)|go:"GO:0051013"(microtubule severing)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR027417|interpro:IPR028594|interpro:IPR028596|interpro:IPR041569|rcsb pdb:6B5C|entrezgene/locuslink:84056(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:mHsNhEvvGEIB7YFXO768m+tkHeU559292	rogid:Usi4KXsvZnNfMOGuWVSz4mfrTaE9606	intact-crc:0DC9D67A4CF9798C|rigid:AfadzUHZucs5QWHSQjJNH2h/fGs	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38302	uniprotkb:Q92733	intact:EBI-20921|uniprotkb:D6VQI3|ensemblfungi:YBR188C	intact:EBI-4397741|uniprotkb:A8K1F7|uniprotkb:O00665|uniprotkb:O00724|uniprotkb:Q5SZ06|ensembl:ENSP00000271526	psi-mi:ntc20_yeast(display_long)|uniprotkb:YBR188C(locus name)|uniprotkb:YBR1316(orf name)|uniprotkb:NTC20(gene name)|psi-mi:NTC20(display_short)|uniprotkb:SNT384(gene name synonym)|uniprotkb:PRP19-associated complex protein 20(gene name synonym)|uniprotkb:Synergistic to PRP19 mutation protein 384(gene name synonym)	psi-mi:prcc_human(display_long)|uniprotkb:PRCC(gene name)|psi-mi:PRCC(display_short)|uniprotkb:TPRC(gene name synonym)|uniprotkb:Papillary renal cell carcinoma translocation-associated gene protein(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11557345|imex:IM-24995-4612	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009747.3|sgd:S000000392|mint:P38302|ensemblfungi:YBR188C(gene)|ensemblfungi:YBR188C_mRNA(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000974"(Prp19 complex)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|dip:DIP-1683N|sgd:YBR188C(identity)	refseq:NP_005964.3|ensembl:ENSG00000143294(gene)|ensembl:ENST00000271526(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0016607"(nuclear speck)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR018800|mint:Q92733|reactome:R-HSA-72163|entrezgene/locuslink:5546(identity)	-	crc64:15C5234B25213223	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Ucc4R0lhhhAQfrsXvs+BtCnuJQg559292	rogid:Q6sXpPQm/3mr9HS0XF0VdxLSFzc9606	intact-crc:0FB87EAB44654725|rigid:CFrGe6z8//a9KmB1lr9NaETc6wU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P43365	uniprotkb:P38302	intact:EBI-749530|uniprotkb:Q9NSD3|intact:EBI-10178394|uniprotkb:Q6FHH8|ensembl:ENSP00000350592|ensembl:ENSP00000377447|ensembl:ENSP00000377478	intact:EBI-20921|uniprotkb:D6VQI3|ensemblfungi:YBR188C	psi-mi:magac_human(display_long)|uniprotkb:MAGE-12 antigen(gene name synonym)|uniprotkb:MAGE12F antigen(gene name synonym)|uniprotkb:Cancer/testis antigen 1.12(gene name synonym)|uniprotkb:MAGEA12(gene name)|psi-mi:MAGEA12(display_short)|uniprotkb:MAGE12(gene name synonym)	psi-mi:ntc20_yeast(display_long)|uniprotkb:YBR188C(locus name)|uniprotkb:YBR1316(orf name)|uniprotkb:NTC20(gene name)|psi-mi:NTC20(display_short)|uniprotkb:SNT384(gene name synonym)|uniprotkb:PRP19-associated complex protein 20(gene name synonym)|uniprotkb:Synergistic to PRP19 mutation protein 384(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11557336|imex:IM-24995-4611	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001159858.1|refseq:NP_001159859.1|refseq:NP_005358.2|ensembl:ENSG00000213401(gene)|ensembl:ENST00000357916(transcript)|ensembl:ENST00000393869(transcript)|ensembl:ENST00000393900(transcript)|interpro:IPR002190(MAGE protein)|interpro:IPR021072|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|entrezgene/locuslink:4111(identity)	refseq:NP_009747.3|sgd:S000000392|mint:P38302|ensemblfungi:YBR188C(gene)|ensemblfungi:YBR188C_mRNA(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000974"(Prp19 complex)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|dip:DIP-1683N|sgd:YBR188C(identity)	-	-	crc64:15C5234B25213223	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:3/Jxz2VsFOb67RWqWj3xbTrw3s49606	rogid:Ucc4R0lhhhAQfrsXvs+BtCnuJQg559292	intact-crc:CF032F16B182D377|rigid:vsfcggVYFPxIV6OVMPdpHABFr28	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38340	intact:EBI-11528223	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	-	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:znf471(display_short)|psi-mi:EBI-11528223(display_long)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11557426|imex:IM-24995-4621	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	entrezgene/locuslink:57573(identity)	-	crc64:66699F37B0013088	no-uniprot-update:	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:x1KdEVhuKo5sZGVPBGE9eyTup9w9606	intact-crc:D2B17F947CD40544|rigid:6nI/DovSV6EE/RcJSsHhQqjEH8g	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
intact:EBI-11528211	uniprotkb:P38340	-	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:enox2(display_short)|psi-mi:EBI-11528211(display_long)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11557417|imex:IM-24995-4620	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	entrezgene/locuslink:10495(identity)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	-	no-uniprot-update:	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:mwLMSKBYuz2EZOAkdg8N9MLSkXE9606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:200726EE3122F7AD|rigid:PeR0wVW3EbiAR3iK/a2zYQ0y6iU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8N5R6	uniprotkb:P38340	intact:EBI-740841|intact:EBI-953781|uniprotkb:B3KQ49|uniprotkb:A8K3U4|uniprotkb:A8MPQ6|uniprotkb:A8MV61|uniprotkb:A8MVU9|uniprotkb:Q9H5Q6|uniprotkb:Q8TAX6|intact:EBI-2320546|intact:EBI-11522976	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:ccd33_human(display_long)|uniprotkb:CCDC33(gene name)|psi-mi:CCDC33(display_short)|uniprotkb:Cancer/testis antigen 61(gene name synonym)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11557408|imex:IM-24995-4619	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_079331.3|interpro:IPR000008(C2 calcium-dependent membrane targeting)|go:"GO:0005777"(peroxisome)|refseq:NP_001274110.1|refseq:NP_877592.2|mint:Q8N5R6|interpro:IPR035892|interpro:IPR039889|entrezgene/locuslink:80125(identity)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	-	-	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2021/11/30	rogid:eEIn7pQyfdHWx8TeLJpYy0i/gww9606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:B70521F5BBB4F7A4|rigid:WXW+UkaLERQjfcPvEM30JXP5Ay8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38339	uniprotkb:Q13490	intact:EBI-15065|uniprotkb:D6VQQ7|ensemblfungi:YBR260C	intact:EBI-514538|uniprotkb:Q16516|uniprotkb:Q4TTG0|uniprotkb:B4E026|ensembl:ENSP00000227758|ensembl:ENSP00000477613	psi-mi:rgd1_yeast(display_long)|uniprotkb:RGD1(gene name)|psi-mi:RGD1(display_short)|uniprotkb:YBR260C(locus name)|uniprotkb:YBR1728(orf name)|uniprotkb:Related GAP domain protein 1(gene name synonym)	psi-mi:birc2_human(display_long)|uniprotkb:Inhibitor of apoptosis protein 2(gene name synonym)|uniprotkb:TNFR2-TRAF-signaling complex protein 2(gene name synonym)|uniprotkb:IAP homolog B(gene name synonym)|uniprotkb:RING finger protein 48(gene name synonym)|uniprotkb:BIRC2(gene name)|psi-mi:BIRC2(display_short)|uniprotkb:API1(gene name synonym)|uniprotkb:MIHB(gene name synonym)|uniprotkb:RNF48(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase BIRC2(gene name synonym)|uniprotkb:Cellular inhibitor of apoptosis 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11557399|imex:IM-24995-4618	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009819.1|sgd:S000000464|ensemblfungi:YBR260C(gene)|ensemblfungi:YBR260C_mRNA(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005628"(prospore membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005933"(cellular bud)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007165"(signal transduction)|go:"GO:0010314"(phosphatidylinositol-5-phosphate binding)|go:"GO:0010447"(response to acidic pH)|go:"GO:0030479"(actin cortical patch)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043332"(mating projection tip)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|interpro:IPR000198(RhoGAP)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR027267|interpro:IPR031160|rcsb pdb:4WPC|rcsb pdb:5MY3|reactome:R-SCE-6798695|reactome:R-SCE-8980692|reactome:R-SCE-9013148|reactome:R-SCE-9013405|reactome:R-SCE-9013423|reactome:R-SCE-9035034|dip:DIP-4950N|mint:P38339|sgd:YBR260C(identity)	refseq:NP_001157.1|refseq:NP_001243095.1|refseq:NP_001243092.1|dip:DIP-33485N|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0045471"(response to ethanol)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051087"(chaperone binding)|go:"GO:0051591"(response to cAMP)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060544"(regulation of necroptotic process)|go:"GO:0060546"(negative regulation of necroptotic process)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070266"(necroptotic process)|go:"GO:0070424"(regulation of nucleotide-binding oligomerization domain containing signaling pathway)|go:"GO:0098770"(FBXO family protein binding)|go:"GO:1901222"(regulation of NIK/NF-kappaB signaling)|go:"GO:1902443"(negative regulation of ripoptosome assembly involved in necroptotic process)|go:"GO:1902523"(positive regulation of protein K63-linked ubiquitination)|go:"GO:1902524"(positive regulation of protein K48-linked ubiquitination)|go:"GO:1902527"(positive regulation of protein monoubiquitination)|go:"GO:2000116"(regulation of cysteine-type endopeptidase activity)|go:"GO:2000377"(regulation of reactive oxygen species metabolic process)|interpro:IPR001315(Caspase Recruitment)|interpro:IPR001370(Proteinase inhibitor I32, inhibitor of apoptosis)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011029(DEATH-like)|interpro:IPR041933|mint:Q13490|rcsb pdb:1QBH|rcsb pdb:2L9M|rcsb pdb:3D9T|rcsb pdb:3D9U|rcsb pdb:3M1D|rcsb pdb:3MUP|rcsb pdb:3OZ1|rcsb pdb:3T6P|rcsb pdb:3UW4|rcsb pdb:4EB9|rcsb pdb:4HY4|rcsb pdb:4HY5|rcsb pdb:4KMN|rcsb pdb:4LGE|rcsb pdb:4LGU|rcsb pdb:4MTI|rcsb pdb:4MU7|rcsb pdb:5M6N|rcsb pdb:6EXW|rcsb pdb:6HPR|rcsb pdb:6W74|rcsb pdb:6W7O|rcsb pdb:6W8I|reactome:R-HSA-111465|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-5213460|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5668541|reactome:R-HSA-5675482|reactome:R-HSA-5676594|reactome:R-HSA-5689880|reactome:R-HSA-937041|ensembl:ENSG00000110330(gene)|ensembl:ENST00000227758(transcript)|ensembl:ENST00000613397(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001741"(XY body)|go:"GO:0001890"(placenta development)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0016740"(transferase activity)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034121"(regulation of toll-like receptor signaling pathway)|go:"GO:0035631"(CD40 receptor complex)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0039535"(regulation of RIG-I signaling pathway)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|entrezgene/locuslink:329(identity)	-	crc64:711D9CC717E9111D	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:xHHGufxy5DvB8ngwbICIkYD3DA8559292	rogid:FOikzyDyDtlv2l69i/WNDNq674A9606	intact-crc:2259FEB8F7C41557|rigid:HaBnP7Z3zycxAx+3jRtT2Z4LiN8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O14641	uniprotkb:P38339	intact:EBI-740850|ensembl:ENSP00000005340|uniprotkb:Q53XM0|uniprotkb:D3DTN3	intact:EBI-15065|uniprotkb:D6VQQ7|ensemblfungi:YBR260C	psi-mi:dvl2_human(display_long)|uniprotkb:DSH homolog 2(gene name synonym)|uniprotkb:DVL2(gene name)|psi-mi:DVL2(display_short)	psi-mi:rgd1_yeast(display_long)|uniprotkb:RGD1(gene name)|psi-mi:RGD1(display_short)|uniprotkb:YBR260C(locus name)|uniprotkb:YBR1728(orf name)|uniprotkb:Related GAP domain protein 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11557390|imex:IM-24995-4617	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004413.1|ensembl:ENSG00000004975(gene)|ensembl:ENST00000005340(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005109"(frizzled binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0007507"(heart development)|go:"GO:0016235"(aggresome)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044340"(canonical Wnt signaling pathway involved in regulation of cell proliferation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0150012"(positive regulation of neuron projection arborization)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008341(Dishevelled-2 region)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:O14641|rcsb pdb:2REY|rcsb pdb:3CBX|rcsb pdb:3CBY|rcsb pdb:3CBZ|rcsb pdb:3CC0|rcsb pdb:4WIP|rcsb pdb:5LNP|rcsb pdb:5SUY|rcsb pdb:5SUZ|rcsb pdb:6IW3|rcsb pdb:6JCK|reactome:R-HSA-201681|reactome:R-HSA-201688|reactome:R-HSA-2028269|reactome:R-HSA-4086400|reactome:R-HSA-4608870|reactome:R-HSA-4641258|reactome:R-HSA-4641262|reactome:R-HSA-5099900|reactome:R-HSA-5368598|reactome:R-HSA-5663220|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9673324|ensembl:ENSP00000005340|dip:DIP-34433N|entrezgene/locuslink:1856(identity)	refseq:NP_009819.1|sgd:S000000464|ensemblfungi:YBR260C(gene)|ensemblfungi:YBR260C_mRNA(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005628"(prospore membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005933"(cellular bud)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007165"(signal transduction)|go:"GO:0010314"(phosphatidylinositol-5-phosphate binding)|go:"GO:0010447"(response to acidic pH)|go:"GO:0030479"(actin cortical patch)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043332"(mating projection tip)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|interpro:IPR000198(RhoGAP)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR027267|interpro:IPR031160|rcsb pdb:4WPC|rcsb pdb:5MY3|reactome:R-SCE-6798695|reactome:R-SCE-8980692|reactome:R-SCE-9013148|reactome:R-SCE-9013405|reactome:R-SCE-9013423|reactome:R-SCE-9035034|dip:DIP-4950N|mint:P38339|sgd:YBR260C(identity)	-	-	crc64:711D9CC717E9111D	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:2Vdc8oRnT4Mz/j+EXQXrL3AszOc9606	rogid:xHHGufxy5DvB8ngwbICIkYD3DA8559292	intact-crc:A77D1AF65215FDEC|rigid:NC2obhGm8+/XWATnLm6RDtrAfj8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:A0A0A0MQS1	uniprotkb:P38340	intact:EBI-11528247|ensembl:ENSP00000220966|ensembl:ENSP00000484458	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:a0a0a0mqs1_human(display_long)|uniprotkb:PYCR3(gene name)|psi-mi:PYCR3(display_short)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11557444|imex:IM-24995-4623	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_075566.2|ensembl:ENSG00000104524(gene)|ensembl:ENSG00000276657(gene)|ensembl:ENST00000220966(transcript)|ensembl:ENST00000616663(transcript)|go:"GO:0004735"(pyrroline-5-carboxylate reductase activity)|go:"GO:0005829"(cytosol)|go:"GO:0045171"(intercellular bridge)|go:"GO:0055129"(L-proline biosynthetic process)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000304(Delta 1-pyrroline-5-carboxylate reductase)|interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|interpro:IPR028939|interpro:IPR029036|interpro:IPR036291|entrezgene/locuslink:65263(identity)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	-	-	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:kN384/dufzrR3P6KOXbFMYoj0zc9606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:3609FEF8F2B6DC91|rigid:/WYBpOjvXMEfItB+e7NBTIhhtco	false	sufficient binding region:13-286	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96A10	uniprotkb:P38340	intact:EBI-10486892|intact:EBI-11528237|ensembl:ENSP00000488921	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:q96a10_human(display_long)|uniprotkb:ERVK3-1(gene name)|psi-mi:ERVK3-1(display_short)|uniprotkb:hCG_2043597(orf name)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11557435|imex:IM-24995-4622	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000142396(gene)|ensembl:ENST00000427361(transcript)|entrezgene/locuslink:113386(identity)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	-	-	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/17	rogid:UGl9ZpnDNz58eECRstJXxM5bj9I9606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:0F1471D39BC8FA84|rigid:YJyo2r0ijA0z/uAq/mMlfx5VD3o	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38340	uniprotkb:E7EUC7	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-11528286|ensembl:ENSP00000411803	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:e7euc7_human(display_long)|uniprotkb:UGP2(gene name)|psi-mi:UGP2(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11557475|imex:IM-24995-4626	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	ensembl:ENSG00000169764(gene)|ensembl:ENST00000445915(transcript)|go:"GO:0003983"("UTP:glucose-1-phosphate uridylyltransferase activity")|go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0006011"(UDP-glucose metabolic process)|interpro:IPR002618(UTP--glucose-1-phosphate uridylyltransferase)|interpro:IPR016267(UTP--glucose-1-phosphate uridylyltransferase, subgroup)|interpro:IPR029044|entrezgene/locuslink:7360(identity)	-	crc64:66699F37B0013088	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:+NfRORYv+EzUaQOJJ7vdI/Plv5o9606	intact-crc:F1D6306C5BE34F92|rigid:H37AqMtrt28Esz0gavvvEKcGlvM	false	-	sufficient binding region:21-517	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38340	uniprotkb:A0A0R4J2E4	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-11525602|ensembl:ENSP00000324292	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:a0a0r4j2e4_human(display_long)|uniprotkb:FBF1(gene name)|psi-mi:FBF1(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11557464|imex:IM-24995-4625	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	ensembl:ENSG00000188878(gene)|ensembl:ENST00000319129(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0060271"(cilium assembly)|go:"GO:0090162"(establishment of epithelial cell polarity)|go:"GO:0097539"(ciliary transition fiber)|interpro:IPR033561|entrezgene/locuslink:85302(identity)	-	crc64:66699F37B0013088	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/03/16	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:N4h8foiP1+HSYZRE7i66zhtqKlQ9606	intact-crc:3D23910F80AE348E|rigid:V5Ib2iPlTNrAWfrrK9eBf406bCo	false	-	sufficient binding region:649-1092	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38340	uniprotkb:P04179	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-716989|intact:EBI-1058533|uniprotkb:P78434|uniprotkb:Q16792|uniprotkb:Q5TCM1|uniprotkb:Q96EE6|uniprotkb:Q9P2Z3|uniprotkb:B2R7R1|uniprotkb:E1P5A9|uniprotkb:B3KUK2|uniprotkb:B4E3K9|intact:EBI-11528264|uniprotkb:B4DL20|ensembl:ENSP00000356022|ensembl:ENSP00000446252	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:sodm_human(display_long)|uniprotkb:SOD2(gene name)|psi-mi:SOD2(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11557455|imex:IM-24995-4624	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	refseq:NP_001019637.1|refseq:NP_000627.2|refseq:NP_001019636.1|refseq:NP_001309743.1|refseq:NP_001309744.1|refseq:NP_001309746.1|refseq:NP_001309748.1|refseq:NP_001309749.1|ensembl:ENSG00000112096(gene)|ensembl:ENST00000367055(transcript)|ensembl:ENST00000538183(transcript)|go:"GO:0000303"(response to superoxide)|go:"GO:0001315"(age-dependent response to reactive oxygen species)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0003069"(acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure)|go:"GO:0003677"(DNA binding)|go:"GO:0004784"(superoxide dismutase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006801"(superoxide metabolic process)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009314"(response to radiation)|go:"GO:0009409"(response to cold)|go:"GO:0010042"(response to manganese ion)|go:"GO:0010043"(response to zinc ion)|go:"GO:0010269"(response to selenium ion)|go:"GO:0010729"(positive regulation of hydrogen peroxide biosynthetic process)|go:"GO:0014823"(response to activity)|go:"GO:0019430"(removal of superoxide radicals)|go:"GO:0019825"(oxygen binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030145"(manganese ion binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0032364"(oxygen homeostasis)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0033591"(response to L-ascorbic acid)|go:"GO:0034021"(response to silicon dioxide)|go:"GO:0035900"(response to isolation stress)|go:"GO:0035902"(response to immobilization stress)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042802"(identical protein binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0050665"(hydrogen peroxide biosynthetic process)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071000"(response to magnetism)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:1902176"(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1902631"(negative regulation of membrane hyperpolarization)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|go:"GO:1905932"(positive regulation of vascular associated smooth muscle cell differentiation involved in phenotypic switching)|interpro:IPR001189(Manganese and iron superoxide dismutase)|interpro:IPR019831|interpro:IPR019832|interpro:IPR019833|interpro:IPR036314|interpro:IPR036324|mint:P04179|rcsb pdb:1AP5|rcsb pdb:1AP6|rcsb pdb:1EM1|rcsb pdb:1JA8|rcsb pdb:1LUV|rcsb pdb:1LUW|rcsb pdb:1MSD|rcsb pdb:1N0J|rcsb pdb:1N0N|rcsb pdb:1PL4|rcsb pdb:1PM9|rcsb pdb:1QNM|rcsb pdb:1SZX|rcsb pdb:1VAR|rcsb pdb:1XDC|rcsb pdb:1XIL|rcsb pdb:1ZTE|rcsb pdb:1ZUQ|rcsb pdb:2ADP|rcsb pdb:2ADQ|rcsb pdb:2GDS|rcsb pdb:2P4K|rcsb pdb:2QKA|rcsb pdb:2QKC|rcsb pdb:3C3S|rcsb pdb:3C3T|rcsb pdb:5GXO|rcsb pdb:5T30|rcsb pdb:5VF9|rcsb pdb:7KKS|rcsb pdb:7KKU|rcsb pdb:7KKW|rcsb pdb:7KLB|reactome:R-HSA-2151201|reactome:R-HSA-3299685|reactome:R-HSA-8862803|reactome:R-HSA-8950505|rcsb pdb:1ZSP|reactome:R-HSA-9615017|entrezgene/locuslink:6648(identity)	-	crc64:66699F37B0013088	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2018/02/26	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:W5bvoLylgk4nEcm5peimceKIBbE9606	intact-crc:D1BEDDD7CE68EEA0|rigid:exJgdTfj27ljprbIWmnpTK9FJm4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38340	uniprotkb:O60232	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-741415|ensembl:ENSP00000312318	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:znrd2_human(display_long)|uniprotkb:ZNRD2(gene name)|psi-mi:ZNRD2(display_short)|uniprotkb:Autoantigen p27(gene name synonym)|uniprotkb:SSSCA1(gene name synonym)|uniprotkb:Sjoegren syndrome/scleroderma autoantigen 1(gene name synonym)|uniprotkb:Zinc ribbon domain-containing protein 2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11557533|imex:IM-24995-4632	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	refseq:NP_006387.1|ensembl:ENSG00000173465(gene)|ensembl:ENST00000309328(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0051301"(cell division)|interpro:IPR009563(Sjogrens syndrome scleroderma autoantigen 1)|rcsb pdb:6HCZ|entrezgene/locuslink:10534(identity)	-	crc64:66699F37B0013088	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:Uou80pZneoL39/0YYzb1TAbiB2I9606	intact-crc:7F5BB16B43CFC59A|rigid:r8e1XvMTUwwFv0utOolzotby7J8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O43791	uniprotkb:P38340	intact:EBI-743549|uniprotkb:Q53HJ1|uniprotkb:B2R6S3|uniprotkb:D3DTW7|ensembl:ENSP00000240327|ensembl:ENSP00000377001|ensembl:ENSP00000420908|ensembl:ENSP00000424119|ensembl:ENSP00000425905|ensembl:ENSP00000426986|ensembl:ENSP00000499562	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:spop_human(display_long)|uniprotkb:HIB homolog 1(gene name synonym)|uniprotkb:Roadkill homolog 1(gene name synonym)|uniprotkb:SPOP(gene name)|psi-mi:SPOP(display_short)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11557524|imex:IM-24995-4631	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001007227.1|refseq:NP_001007228.1|refseq:NP_001007229.1|refseq:NP_001007230.1|refseq:NP_001007231.1|refseq:NP_003554.1|refseq:XP_005257780.1|refseq:XP_005257781.1|ensembl:ENSG00000121067(gene)|ensembl:ENST00000347630(transcript)|ensembl:ENST00000393328(transcript)|ensembl:ENST00000503676(transcript)|ensembl:ENST00000504102(transcript)|ensembl:ENST00000509079(transcript)|ensembl:ENST00000514121(transcript)|ensembl:ENST00000665825(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0016607"(nuclear speck)|go:"GO:0030162"(regulation of proteolysis)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR034089|mint:O43791|rcsb pdb:2CR2|rcsb pdb:3HQH|rcsb pdb:3HQI|rcsb pdb:3HQL|rcsb pdb:3HQM|rcsb pdb:3HSV|rcsb pdb:3HTM|rcsb pdb:3HU6|rcsb pdb:3IVB|rcsb pdb:3IVQ|rcsb pdb:3IVV|rcsb pdb:4EOZ|rcsb pdb:4HS2|rcsb pdb:4J8Z|rcsb pdb:4O1V|rcsb pdb:6F8F|rcsb pdb:6F8G|rcsb pdb:6I41|rcsb pdb:6I5P|rcsb pdb:6I68|rcsb pdb:6I7A|rcsb pdb:7D3D|rcsb pdb:7LIN|rcsb pdb:7LIO|rcsb pdb:7LIP|rcsb pdb:7LIQ|reactome:R-HSA-5632684|go:"GO:0005634"(nucleus)|refseq:XP_016880693.1|dip:DIP-50517N|entrezgene/locuslink:8405(identity)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	-	-	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:PC9ofpvk14xwTnnqT590/YRnx/49606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:727E65E8CECD50D3|rigid:t/pDXBo/dfZ4YElZ7GMLcsDBsrA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O15217	uniprotkb:P38340	intact:EBI-752440|uniprotkb:Q5T7Q8|uniprotkb:Q9BX18|uniprotkb:Q9H414|uniprotkb:B2RD15|uniprotkb:Q6P4G1|ensembl:ENSP00000359998|ensembl:ENSP00000360002	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:gsta4_human(display_long)|uniprotkb:Glutathione S-transferase A4-4(gene name synonym)|uniprotkb:GST class-alpha member 4(gene name synonym)|uniprotkb:GSTA4(gene name)|psi-mi:GSTA4(display_short)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11557515|imex:IM-24995-4630	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001503.1|refseq:XP_005249092.1|ensembl:ENSG00000170899(gene)|ensembl:ENST00000370959(transcript)|ensembl:ENST00000370963(transcript)|go:"GO:0004364"(glutathione transferase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0006805"(xenobiotic metabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|interpro:IPR003080(Glutathione S-transferase, alpha class)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR036249|interpro:IPR036282|interpro:IPR040079|rcsb pdb:1GUL|rcsb pdb:1GUM|rcsb pdb:3IK7|reactome:R-HSA-156590|entrezgene/locuslink:2941(identity)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	-	-	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:9yVcqmJL64S0kxOW5RJWbOJ25bo9606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:BC06D3E00A9A3491|rigid:CQe1YtkJPmZO9D7RLFGMIU2cnpo	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O00635	uniprotkb:P38340	intact:EBI-2130415|uniprotkb:B2R862|ensembl:ENSP00000349596	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:tri38_human(display_long)|uniprotkb:TRIM38(gene name)|psi-mi:TRIM38(display_short)|uniprotkb:RNF15(gene name synonym)|uniprotkb:RORET(gene name synonym)|uniprotkb:RING finger protein 15(gene name synonym)|uniprotkb:Zinc finger protein RoRet(gene name synonym)|uniprotkb:Tripartite motif-containing protein 38(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM38(gene name synonym)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11557506|imex:IM-24995-4629	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006346.1|refseq:XP_005248856.1|refseq:XP_005248857.1|ensembl:ENSG00000112343(gene)|ensembl:ENST00000357085(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046598"(positive regulation of viral entry into host cell)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR035790|interpro:IPR043136|reactome:R-HSA-877300|entrezgene/locuslink:10475(identity)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	-	-	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Zh4X/6v/qKZlDkMV6hhn7OsvPnQ9606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:10D40CB0FDF8D667|rigid:PSSGJVXhFQXVtirX3AU6PNf5XwQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38340	uniprotkb:O00463	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-523498|ensembl:ENSP00000261464|ensembl:ENSP00000336825|ensembl:ENSP00000355971|uniprotkb:Q6FHY1|uniprotkb:B4DIS9|uniprotkb:B4E0A2	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:traf5_human(display_long)|uniprotkb:RING finger protein 84(gene name synonym)|uniprotkb:TRAF5(gene name)|psi-mi:TRAF5(display_short)|uniprotkb:RNF84(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11557497|imex:IM-24995-4628	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	refseq:NP_001306136.1|refseq:XP_011508261.1|refseq:XP_011508262.1|ensembl:ENSG00000082512(gene)|ensembl:ENST00000261464(transcript)|ensembl:ENST00000336184(transcript)|ensembl:ENST00000367004(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031996"(thioesterase binding)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035631"(CD40 receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0097400"(interleukin-17-mediated signaling pathway)|interpro:IPR001293(Zinc finger, TRAF-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|interpro:IPR012227(TNF receptor-associated factor TRAF)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018957|interpro:IPR027130|interpro:IPR043211|mint:O00463|rcsb pdb:7L3L|refseq:NP_001029082.1|refseq:NP_004610.1|refseq:NP_665702.1|refseq:XP_016857710.1|entrezgene/locuslink:7188(identity)	-	crc64:66699F37B0013088	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:xPAQGevMJLEAPcT6eX3n304eSOw9606	intact-crc:FE6ABDE5A1FDE9D0|rigid:pkuLBc2UxLhn82KLCoJBiJlN04M	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q7Z6G3-2	uniprotkb:P38340	intact:EBI-10172876|ensembl:ENSP00000457354|intact:EBI-14062040	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:q7z6g3-2(display_long)|uniprotkb:EFCBP2(gene name synonym)|uniprotkb:Neuronal calcium-binding protein 2(gene name synonym)|uniprotkb:Synaptotagmin-interacting protein 2(gene name synonym)|uniprotkb:NECAB2(gene name)|psi-mi:NECAB2(display_short)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11557486|imex:IM-24995-4627	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000103154(gene)|ensembl:ENST00000565691(transcript)|uniprotkb:Q7Z6G3-2(isoform-parent)|intact:EBI-950070(isoform-parent)|entrezgene/locuslink:54550(identity)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	-	-	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:4S7oIx6h+mKzV3EPxqcfMNqaNko9606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:1A9F09EB83C567E9|rigid:HePbFZ6mzdKTou/1BHktJZUUsEk	false	sufficient binding region:65-303	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38340	uniprotkb:O95198	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-746999|uniprotkb:B2RD18|uniprotkb:Q8N484|uniprotkb:Q8TBH5|uniprotkb:A6NCM7|uniprotkb:B4DFH7|uniprotkb:F5H6M3|ensembl:ENSP00000226725	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:klhl2_human(display_long)|uniprotkb:Actin-binding protein Mayven(gene name synonym)|uniprotkb:KLHL2(gene name)|psi-mi:KLHL2(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11557589|imex:IM-24995-4638	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	refseq:NP_001154993.1|refseq:NP_001154994.1|refseq:NP_009177.3|refseq:NP_001317952.1|refseq:NP_001317953.1|refseq:XP_016863165.1|ensembl:ENSG00000109466(gene)|ensembl:ENST00000226725(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030027"(lamellipodium)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR017096(Kelch-like protein, gigaxonin)|interpro:IPR044072|mint:O95198|rcsb pdb:2XN4|rcsb pdb:4CHB|reactome:R-HSA-8951664|reactome:R-HSA-983168|go:"GO:0042802"(identical protein binding)|entrezgene/locuslink:11275(identity)	-	crc64:66699F37B0013088	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:tFegR2lJZccRqs4qUjdT3PNjNnk9606	intact-crc:1096FE13320EC55D|rigid:lJxC0eiGxMGHHLeQdu8zDmVW8Ps	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38340	uniprotkb:O95073-2	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-10696047	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:o95073-2(display_long)|uniprotkb:FSBP(gene name)|psi-mi:FSBP(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11557580|imex:IM-24995-4637	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	intact:EBI-1059030(isoform-parent)|uniprotkb:O95073-2(isoform-parent)|entrezgene/locuslink:25788(identity)	-	crc64:66699F37B0013088	isoform-comment:No experimental confirmation available.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:j4ktleFZa7rAjRFENAKAGdAd+Fs9606	intact-crc:1032CE91A4DC88F5|rigid:3CHju8AVHoaJuwXoNLMo4eK2jk4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38340	uniprotkb:O95045-2	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-11528386|ensembl:ENSP00000474090	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:o95045-2(display_long)|uniprotkb:UPP2(gene name)|psi-mi:UPP2(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11557569|imex:IM-24995-4636	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	intact:EBI-10191025(isoform-parent)|ensembl:ENSG00000007001(gene)|ensembl:ENST00000605860(transcript)|uniprotkb:O95045-2(isoform-parent)|entrezgene/locuslink:151531(identity)	-	crc64:66699F37B0013088	isoform-comment:No experimental confirmation available.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:owY6a3SJ4JVsFePCTPW+NLGK6QQ9606	intact-crc:C45B670C97047AC6|rigid:V72wliDv5yx9hOM+q/HouxwfR5E	false	-	sufficient binding region:58-374	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O75525	uniprotkb:P38340	intact:EBI-722504|uniprotkb:Q6NUL8|uniprotkb:Q9UPA8|ensembl:ENSP00000348108	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:khdr3_human(display_long)|uniprotkb:Sam68-like mammalian protein 2(gene name synonym)|uniprotkb:Sam68-like phosphotyrosine protein(gene name synonym)|uniprotkb:RNA-binding protein T-Star(gene name synonym)|uniprotkb:KHDRBS3(gene name)|psi-mi:KHDRBS3(display_short)|uniprotkb:SALP(gene name synonym)|uniprotkb:SLM2(gene name synonym)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11557560|imex:IM-24995-4635	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006549.1|ensembl:ENSG00000131773(gene)|ensembl:ENST00000355849(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR032335|interpro:IPR032571|interpro:IPR036612|mint:O75525|rcsb pdb:5EL3|rcsb pdb:5ELR|rcsb pdb:5ELS|rcsb pdb:5ELT|rcsb pdb:5EMO|reactome:R-HSA-8849468|entrezgene/locuslink:10656(identity)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	-	-	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:9ZoB3JVp0Q9nxeFRsmWhNThzWoE9606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:DC3C8C17D7A663FF|rigid:HE8C5amJM/2YjlkjyDW3gJAZjtA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O75150	uniprotkb:P38340	intact:EBI-744408|uniprotkb:Q6AHZ6|uniprotkb:Q6N005|uniprotkb:Q7L3T6|uniprotkb:Q8N615|uniprotkb:Q96T18|uniprotkb:Q9BSV9|uniprotkb:Q9HC82|ensembl:ENSP00000325677|uniprotkb:A0A024QZG0	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:bre1b_human(display_long)|uniprotkb:95 kDa retinoblastoma-associated protein(gene name synonym)|uniprotkb:RING finger protein 40(gene name synonym)|uniprotkb:RNF40(gene name)|psi-mi:RNF40(display_short)|uniprotkb:BRE1B(gene name synonym)|uniprotkb:KIAA0661(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase BRE1B(gene name synonym)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11557551|imex:IM-24995-4634	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001273501.1|refseq:NP_001193962.1|refseq:NP_001193963.1|refseq:NP_055586.1|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|go:"GO:1902916"(positive regulation of protein polyubiquitination)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013956(E3 ubiquitin ligase, BRE1)|interpro:IPR017907|mint:O75150|reactome:R-HSA-8866654|go:"GO:0046872"(metal ion binding)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0043679"(axon terminus)|go:"GO:0044877"(protein-containing complex binding)|ensembl:ENSG00000103549(gene)|ensembl:ENST00000324685(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016020"(membrane)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0033503"(HULC complex)|entrezgene/locuslink:9810(identity)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	-	-	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2018/09/18	rogid:POkQZhEBe4cw3Y9V3YOwJDgvYJ89606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:4ECAEFD10D6677C9|rigid:Sy3yc2wsAABEI+8dEkNmd7HhUCI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38340	uniprotkb:O60547	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-746373|uniprotkb:O75357|uniprotkb:Q5T954|uniprotkb:Q6FH09|uniprotkb:Q9UGZ3|uniprotkb:Q9UJK9|ensembl:ENSP00000370194|intact:EBI-10968896|uniprotkb:E9PI88	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:gmds_human(display_long)|uniprotkb:GDP-D-mannose dehydratase(gene name synonym)|uniprotkb:GMDS(gene name)|psi-mi:GMDS(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11557542|imex:IM-24995-4633	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	refseq:NP_001491.1|ensembl:ENSG00000112699(gene)|ensembl:ENST00000380815(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0008446"(GDP-mannose 4,6-dehydratase activity)|go:"GO:0019673"(GDP-mannose metabolic process)|go:"GO:0042351"('de novo' GDP-L-fucose biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070401"(NADP+ binding)|interpro:IPR006368(GDP-mannose 4,6-dehydratase)|interpro:IPR016040("NAD(P)-binding")|interpro:IPR036291|rcsb pdb:1T2A|rcsb pdb:5IN4|rcsb pdb:5IN5|rcsb pdb:6GPJ|rcsb pdb:6GPK|rcsb pdb:6GPL|rcsb pdb:6Q94|reactome:R-HSA-6787639|refseq:NP_001240775.1|entrezgene/locuslink:2762(identity)	-	crc64:66699F37B0013088	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:phGw3/m75gYQcBlRP3OXK4mQvhM9606	intact-crc:1AC1AD9E3555BB97|rigid:PrxLMY8mTgPT6dYfmKllhPebQmA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P07910	uniprotkb:P38340	intact:EBI-357966|uniprotkb:P22628|uniprotkb:Q53EX2|uniprotkb:Q59FD3|uniprotkb:Q5FWE8|uniprotkb:Q86SF8|uniprotkb:Q86U45|uniprotkb:Q96HK7|uniprotkb:Q96HM4|uniprotkb:Q96IY5|uniprotkb:Q9BTS3|uniprotkb:D3DS19|uniprotkb:D3DS22|intact:EBI-28976506|ensembl:ENSP00000404848|ensembl:ENSP00000451291|ensembl:ENSP00000452276	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:hnrpc_human(display_long)|uniprotkb:HNRNPC(gene name)|psi-mi:HNRNPC(display_short)|uniprotkb:HNRPC(gene name synonym)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11557645|imex:IM-24995-4644	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001070910.1|refseq:NP_001070911.1|refseq:NP_004491.2|refseq:NP_112604.2|ensembl:ENSP00000404848|ensembl:ENST00000430246|ensembl:ENSP00000442816|ensembl:ENST00000553300|ensembl:ENSP00000450544|ensembl:ENSP00000451291|ensembl:ENST00000554969|ensembl:ENSP00000452276|ensembl:ENSP00000450725|ensembl:ENST00000555883|ensembl:ENSP00000450629|ensembl:ENST00000556628|ensembl:ENSP00000451652|ensembl:ENST00000556897|ensembl:ENSP00000451176|refseq:XP_011535010.1|refseq:XP_011535011.1|refseq:XP_011535012.1|refseq:XP_011535013.1|refseq:XP_011535014.1|refseq:XP_016876741.1|refseq:XP_016876742.1|dip:DIP-29854N|refseq:XP_006720188.1|ensembl:ENSG00000092199(gene)|ensembl:ENST00000420743(transcript)|ensembl:ENST00000554455(transcript)|ensembl:ENST00000557201(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000785"(chromatin)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005829"(cytosol)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0008380"(RNA splicing)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043044"|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070935"(3'-UTR-mediated mRNA stabilization)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990247"(N6-methyladenosine-containing RNA binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR017347(Heterogeneous nuclear ribonucleoprotein C, Raly)|interpro:IPR035979|mint:P07910|rcsb pdb:1TXP|rcsb pdb:1WF2|rcsb pdb:2MXY|rcsb pdb:2MZ1|rcsb pdb:3LN4|reactome:R-HSA-4570464|reactome:R-HSA-72163|reactome:R-HSA-72203|reactome:R-HSA-9013418|reactome:R-HSA-9013422|entrezgene/locuslink:3183(identity)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	-	-	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Fj5tiH0wrNUjTnsURIg8dB8laMg9606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:DE8C4231BFFF2E16|rigid:/dGmj8DEWCpiwUdODoXbKQWMeJI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38340	uniprotkb:P07195	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-358748|ensembl:ENSP00000229319|ensembl:ENSP00000379386	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:ldhb_human(display_long)|uniprotkb:LDHB(gene name)|psi-mi:LDHB(display_short)|uniprotkb:LDH heart subunit(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-46(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11557636|imex:IM-24995-4643	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	refseq:NP_001167568.1|refseq:NP_002291.1|refseq:NP_001302466.1|ensembl:ENSG00000111716(gene)|ensembl:ENST00000350669(transcript)|ensembl:ENST00000396076(transcript)|go:"GO:0004459"(L-lactate dehydrogenase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0019752"(carboxylic acid metabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0045121"(membrane raft)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001236(Lactate/malate dehydrogenase)|interpro:IPR001557(L-lactate/malate dehydrogenase)|interpro:IPR011304(L-lactate dehydrogenase)|interpro:IPR015955(Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal)|interpro:IPR018177|interpro:IPR022383|interpro:IPR036291|mint:P07195|rcsb pdb:1I0Z|rcsb pdb:1T2F|reactome:R-HSA-70268|entrezgene/locuslink:3945(identity)	-	crc64:66699F37B0013088	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:umdj6fjSO7+4SM9Hrl1/K2EiKls9606	intact-crc:A1C03AB584F36214|rigid:u8nJ3fWsXWTbmmVX+FV2vOEmMDQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38340	uniprotkb:P02792	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-713279|uniprotkb:Q7Z2W1|uniprotkb:Q9BTZ8|ensembl:ENSP00000366525|uniprotkb:B2R4B9|uniprotkb:Q6IBT7|uniprotkb:Q86WI9|uniprotkb:Q8WU07|uniprotkb:Q96AU9|uniprotkb:Q96CU0	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:fril_human(display_long)|uniprotkb:FTL(gene name)|psi-mi:FTL(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11557625|imex:IM-24995-4642	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	refseq:NP_000137.2|ensembl:ENSG00000087086(gene)|ensembl:ENST00000331825(transcript)|go:"GO:0005506"(iron ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006826"(iron ion transport)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0006880"(intracellular sequestering of iron ion)|go:"GO:0008043"(intracellular ferritin complex)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008199"(ferric iron binding)|go:"GO:0016020"(membrane)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0042802"(identical protein binding)|go:"GO:0044754"(autolysosome)|go:"GO:0055072"(iron ion homeostasis)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001519(Ferritin, N-terminal)|interpro:IPR008331(Ferritin and Dps)|interpro:IPR009040(Ferritin-like)|interpro:IPR009078(Ferritin/ribonucleotide reductase-like)|interpro:IPR012347(Ferritin-related)|interpro:IPR014034(Ferritin, conserved site)|mint:P02792|rcsb pdb:2FFX|rcsb pdb:2FG4|rcsb pdb:2FG8|rcsb pdb:3KXU|rcsb pdb:4V6B|rcsb pdb:5LG8|rcsb pdb:6TR9|rcsb pdb:6TS0|rcsb pdb:6TS1|rcsb pdb:6TSA|rcsb pdb:6TSF|rcsb pdb:6TSJ|rcsb pdb:6WX6|reactome:R-HSA-3000480|reactome:R-HSA-432722|reactome:R-HSA-6798695|reactome:R-HSA-917937|dip:DIP-31248N|entrezgene/locuslink:2512(identity)	-	crc64:66699F37B0013088	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:+mbnoETQ9TuBZg8Gc09nwAjwKTE9606	intact-crc:55D3EAB64A13F1C2|rigid:WAT4Ve4kETxjryeBc7GwTF2nUqk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38340	uniprotkb:P00492	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-748210|uniprotkb:A6NHF0|uniprotkb:B2R8M9|ensembl:ENSP00000298556	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:hprt_human(display_long)|uniprotkb:HPRT1(gene name)|psi-mi:HPRT1(display_short)|uniprotkb:HPRT(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11557616|imex:IM-24995-4641	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	refseq:NP_000185.1|ensembl:ENSG00000165704(gene)|ensembl:ENST00000298556(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001913"(T cell mediated cytotoxicity)|go:"GO:0001975"(response to amphetamine)|go:"GO:0004422"(hypoxanthine phosphoribosyltransferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006164"(purine nucleotide biosynthetic process)|go:"GO:0006166"(purine ribonucleoside salvage)|go:"GO:0006168"(adenine salvage)|go:"GO:0006178"(guanine salvage)|go:"GO:0007625"(grooming behavior)|go:"GO:0007626"(locomotory behavior)|go:"GO:0021756"(striatum development)|go:"GO:0021895"(cerebral cortex neuron differentiation)|go:"GO:0021954"(central nervous system neuron development)|go:"GO:0032263"(GMP salvage)|go:"GO:0032264"(IMP salvage)|go:"GO:0042417"(dopamine metabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043103"(hypoxanthine salvage)|go:"GO:0045964"(positive regulation of dopamine metabolic process)|go:"GO:0046038"(GMP catabolic process)|go:"GO:0046040"(IMP metabolic process)|go:"GO:0046100"(hypoxanthine metabolic process)|go:"GO:0046651"(lymphocyte proliferation)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0052657"(guanine phosphoribosyltransferase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000836(Phosphoribosyltransferase)|interpro:IPR005904(Hypoxanthine phosphoribosyl transferase)|interpro:IPR029057|mint:P00492|rcsb pdb:1BZY|rcsb pdb:1D6N|rcsb pdb:1HMP|rcsb pdb:1Z7G|go:"GO:0048813"(dendrite morphogenesis)|rcsb pdb:2VFA|rcsb pdb:3GEP|rcsb pdb:3GGC|rcsb pdb:3GGJ|rcsb pdb:4IJQ|rcsb pdb:4KN6|rcsb pdb:4RAB|rcsb pdb:4RAC|rcsb pdb:4RAD|rcsb pdb:4RAN|rcsb pdb:4RAO|rcsb pdb:4RAQ|rcsb pdb:5BRN|rcsb pdb:5BSK|rcsb pdb:5HIA|rcsb pdb:5W8V|rcsb pdb:6BNJ|reactome:R-HSA-74217|entrezgene/locuslink:3251(identity)	-	crc64:66699F37B0013088	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:w87Sv/qOAkHFqJm0vu0Ayqlz7TA9606	intact-crc:42E3D94F0100CDA7|rigid:kN3HSjFHCL+psSPe3dh3+6GQJ0o	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38340	uniprotkb:O96006	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-740037|uniprotkb:Q96BY4|ensembl:ENSP00000370616|ensembl:ENSP00000370620|ensembl:ENSP00000370621|ensembl:ENSP00000498725	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:zbed1_human(display_long)|uniprotkb:ZBED1(gene name)|psi-mi:ZBED1(display_short)|uniprotkb:ALTE(gene name synonym)|uniprotkb:DREF(gene name synonym)|uniprotkb:KIAA0785(gene name synonym)|uniprotkb:TRAMP(gene name synonym)|uniprotkb:dREF homolog(gene name synonym)|uniprotkb:Putative Ac-like transposable element(gene name synonym)|uniprotkb:DNA replication-related element-binding factor(gene name synonym)|uniprotkb:Zinc finger BED domain-containing protein 1(gene name synonym)|uniprotkb:hDREF(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11557607|imex:IM-24995-4640	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	refseq:NP_001164606.1|refseq:NP_001164607.1|refseq:NP_004720.1|ensembl:ENSG00000214717(gene)|ensembl:ENST00000381218(transcript)|ensembl:ENST00000381222(transcript)|ensembl:ENST00000381223(transcript)|ensembl:ENST00000652001(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0031965"(nuclear membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044828"(negative regulation by host of viral genome replication)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0061665"(SUMO ligase activity)|go:"GO:1990466"(protein autosumoylation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003656(Zinc finger, BED-type predicted)|interpro:IPR008906(HAT dimerisation)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR036236|mint:O96006|rcsb pdb:2CT5|reactome:R-HSA-4551638|go:"GO:0005813"(centrosome)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016605"(PML body)|entrezgene/locuslink:9189(identity)	-	crc64:66699F37B0013088	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:jl97ZV2Kz5YAmQKktWt/wk7OkRw9606	intact-crc:FBC454E6BD37D396|rigid:OsutfvhFYaGz8t3mj3RghBXI6Xw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O95199	uniprotkb:P38340	intact:EBI-742404|uniprotkb:B2RDW8|ensembl:ENSP00000345144	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:rcbt2_human(display_long)|uniprotkb:RCBTB2(gene name)|psi-mi:RCBTB2(display_short)|uniprotkb:CHC1L(gene name synonym)|uniprotkb:RLG(gene name synonym)|uniprotkb:Regulator of chromosome condensation and BTB domain-containing protein 2(gene name synonym)|uniprotkb:Chromosome condensation 1-like(gene name synonym)|uniprotkb:RCC1-like G exchanging factor(gene name synonym)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11557598|imex:IM-24995-4639	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001259.1|refseq:NP_001273759.1|refseq:NP_001273760.1|refseq:NP_001273761.1|refseq:XP_005266299.1|refseq:XP_005266301.1|refseq:XP_006719822.1|ensembl:ENSG00000136161(gene)|ensembl:ENST00000344532(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR000408(Regulator of chromosome condensation, RCC1)|interpro:IPR009091(Regulator of chromosome condensation/beta-lactamase-inhibitor protein II)|interpro:IPR011333(BTB/POZ fold)|entrezgene/locuslink:1102(identity)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	-	-	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:VJjauSy5q9k4V5QceqoSYZQ5ep49606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:D14428DAAB8868C2|rigid:AprCXFdpSyNS16xZwsp7R5S4ILk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38340	uniprotkb:P35520	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-740135|uniprotkb:Q99425|uniprotkb:Q9BWC5|uniprotkb:B2R993|uniprotkb:D3DSK4|intact:EBI-14245939|ensembl:ENSP00000344460|ensembl:ENSP00000352643|ensembl:ENSP00000381225|ensembl:ENSP00000381231	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:cbs_human(display_long)|uniprotkb:CBS(gene name)|psi-mi:CBS(display_short)|uniprotkb:Serine sulfhydrase(gene name synonym)|uniprotkb:Beta-thionase(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11557699|imex:IM-24995-4650	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	refseq:NP_000062.1|refseq:NP_001171479.1|refseq:NP_001171480.1|ensembl:ENSG00000160200(gene)|ensembl:ENST00000352178(transcript)|ensembl:ENST00000359624(transcript)|ensembl:ENST00000398158(transcript)|go:"GO:0004122"(cystathionine beta-synthase activity)|ensembl:ENST00000398165(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006535"(cysteine biosynthetic process from serine)|go:"GO:0006563"(L-serine metabolic process)|go:"GO:0006565"(L-serine catabolic process)|go:"GO:0019343"(cysteine biosynthetic process via cystathionine)|go:"GO:0019344"(cysteine biosynthetic process)|go:"GO:0019346"(transsulfuration)|go:"GO:0019448"(L-cysteine catabolic process)|go:"GO:0019825"(oxygen binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0020037"(heme binding)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042262"(DNA protection)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043418"(homocysteine catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0050421"("nitrite reductase (NO-forming) activity")|go:"GO:0050667"(homocysteine metabolic process)|go:"GO:0070025"(carbon monoxide binding)|go:"GO:0070026"(nitric oxide binding)|go:"GO:0070814"(hydrogen sulfide biosynthetic process)|go:"GO:0072341"(modified amino acid binding)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR001216(Cysteine synthase/cystathionine beta-synthase P-phosphate-binding site)|interpro:IPR001926(Pyridoxal phosphate-dependent enzyme, beta subunit)|interpro:IPR005857(Cystathionine beta-synthase)|interpro:IPR036052|mint:P35520|rcsb pdb:1JBQ|rcsb pdb:1M54|rcsb pdb:4COO|rcsb pdb:4L0D|rcsb pdb:4L27|rcsb pdb:4L28|rcsb pdb:4L3V|rcsb pdb:4PCU|rcsb pdb:4UUU|rcsb pdb:5MMS|reactome:R-HSA-1614603|reactome:R-HSA-2408508|refseq:XP_011528079.1|refseq:XP_011528083.1|refseq:XP_011528084.1|refseq:XP_011544396.1|refseq:XP_011544397.1|refseq:XP_011544399.1|refseq:XP_011544400.1|refseq:XP_011544401.1|refseq:NP_001307227.1|refseq:NP_001308002.1|refseq:XP_016883700.1|refseq:XP_016883701.1|refseq:XP_016883702.1|refseq:XP_016883703.1|refseq:XP_016883704.1|refseq:XP_016883705.1|refseq:XP_016883706.1|refseq:XP_016883707.1|refseq:XP_016883978.1|refseq:XP_016883979.1|refseq:XP_016883980.1|refseq:XP_016883981.1|entrezgene/locuslink:875(identity)	-	crc64:66699F37B0013088	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:f9eo0cPOHppVY7Nqejag3YyK18s9606	intact-crc:F5A5C646F1F8781C|rigid:UctRQejoRQJyfKCSH+eIvdt/Fx0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38340	uniprotkb:P23511-2	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-11061759|ensembl:ENSP00000229418	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:p23511-2(display_long)|uniprotkb:NFYA(gene name)|psi-mi:NFYA(display_short)|uniprotkb:CAAT box DNA-binding protein subunit A(gene name synonym)|uniprotkb:Nuclear transcription factor Y subunit A(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11557690|imex:IM-24995-4649	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	intact:EBI-389739(isoform-parent)|ensembl:ENSG00000001167(gene)|ensembl:ENST00000353205(transcript)|uniprotkb:P23511-2(isoform-parent)|entrezgene/locuslink:4800(identity)	-	crc64:66699F37B0013088	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:9IOUoaGszX6kd9hzrCj6BBkgJ+09606	intact-crc:FEC142D759E0BDDF|rigid:G3HyeGy+Y4dllNBePDME7Qpu6I8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38340	uniprotkb:P20591	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-929476|uniprotkb:D3DSI8|uniprotkb:B2RDA5|uniprotkb:B3KU10|uniprotkb:C9IYV7|uniprotkb:C9J8D6|uniprotkb:C9JN19|uniprotkb:C9JN88|uniprotkb:C9JUL1|uniprotkb:C9JZS6|uniprotkb:Q86YP5|uniprotkb:Q96CI3|ensembl:ENSP00000381599|ensembl:ENSP00000381601|ensembl:ENSP00000392151|ensembl:ENSP00000402215|ensembl:ENSP00000408498|ensembl:ENSP00000410523|ensembl:ENSP00000505029|ensembl:ENSP00000505047|ensembl:ENSP00000505051|ensembl:ENSP00000505189|ensembl:ENSP00000505457|ensembl:ENSP00000505489|ensembl:ENSP00000505630|ensembl:ENSP00000505657|ensembl:ENSP00000505669|ensembl:ENSP00000505781|ensembl:ENSP00000505874|ensembl:ENSP00000506047|ensembl:ENSP00000506062|ensembl:ENSP00000506183|ensembl:ENSP00000506199|ensembl:ENSP00000506220|ensembl:ENSP00000506270|ensembl:ENSP00000506348|ensembl:ENSP00000506372|ensembl:ENSP00000506395|ensembl:ENSP00000506481|ensembl:ENSP00000506512|ensembl:ENSP00000506690|ensembl:ENSP00000506712	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:mx1_human(display_long)|uniprotkb:MX1(gene name)|psi-mi:MX1(display_short)|uniprotkb:Myxovirus resistance protein 1(gene name synonym)|uniprotkb:Interferon-regulated resistance GTP-binding protein MxA(gene name synonym)|uniprotkb:Interferon-induced protein p78(gene name synonym)|uniprotkb:Myxoma resistance protein 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11557681|imex:IM-24995-4648	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	refseq:NP_001269849.1|refseq:NP_001138397.1|refseq:NP_001171517.1|refseq:NP_002453.2|refseq:XP_011527870.1|refseq:XP_005261037.1|refseq:XP_005261038.1|refseq:XP_005261039.1|refseq:XP_005261035.1|refseq:XP_005261036.1|refseq:XP_016883838.1|refseq:XP_016883839.1|dip:DIP-35694N|ensembl:ENSG00000157601(gene)|ensembl:ENST00000398598(transcript)|ensembl:ENST00000398600(transcript)|ensembl:ENST00000413778(transcript)|ensembl:ENST00000417963(transcript)|ensembl:ENST00000419044(transcript)|ensembl:ENST00000455164(transcript)|ensembl:ENST00000679445(transcript)|ensembl:ENST00000679464(transcript)|ensembl:ENST00000679543(transcript)|ensembl:ENST00000679626(transcript)|ensembl:ENST00000679705(transcript)|ensembl:ENST00000679911(transcript)|ensembl:ENST00000680176(transcript)|ensembl:ENST00000680182(transcript)|ensembl:ENST00000680347(transcript)|ensembl:ENST00000680364(transcript)|ensembl:ENST00000680536(transcript)|ensembl:ENST00000680629(transcript)|ensembl:ENST00000680760(transcript)|ensembl:ENST00000680776(transcript)|ensembl:ENST00000681039(transcript)|ensembl:ENST00000681191(transcript)|ensembl:ENST00000681266(transcript)|ensembl:ENST00000681415(transcript)|ensembl:ENST00000681607(transcript)|ensembl:ENST00000681671(transcript)|ensembl:ENST00000681849(transcript)|ensembl:ENST00000681857(transcript)|ensembl:ENST00000681867(transcript)|ensembl:ENST00000681896(transcript)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0003374"(dynamin family protein polymerization involved in mitochondrial fission)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0006952"(defense response)|go:"GO:0007165"(signal transduction)|go:"GO:0008017"(microtubule binding)|go:"GO:0009615"(response to virus)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016185"(synaptic vesicle budding from presynaptic endocytic zone membrane)|go:"GO:0030424"(axon)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031623"(receptor internalization)|go:"GO:0031965"(nuclear membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0034340"(response to type I interferon)|go:"GO:0042802"(identical protein binding)|go:"GO:0044327"(dendritic spine head)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0051607"(defense response to virus)|go:"GO:0061025"(membrane fusion)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:0098793"(presynapse)|go:"GO:0098844"(postsynaptic endocytic zone membrane)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:0140374"(antiviral innate immune response)|interpro:IPR000375(Dynamin central region)|interpro:IPR001401(Dynamin, GTPase region)|interpro:IPR003130(Dynamin GTPase effector)|interpro:IPR019762|interpro:IPR020850|interpro:IPR022812|interpro:IPR027417|interpro:IPR030381|mint:P20591|rcsb pdb:3LJB|rcsb pdb:3SZR|rcsb pdb:3ZYS|rcsb pdb:4P4S|rcsb pdb:4P4T|rcsb pdb:4P4U|rcsb pdb:5GTM|reactome:R-HSA-1169408|reactome:R-HSA-909733|entrezgene/locuslink:4599(identity)	-	crc64:66699F37B0013088	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:9rO7Zyl6v0Kq3xw6MKbVefk1hCA9606	intact-crc:7793364F51A5438D|rigid:2isHB41HHZLGGKSn1+EQx02KZHg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38340	uniprotkb:P15531	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-741141|ensembl:ENSP00000376892|uniprotkb:Q6FGK3|uniprotkb:Q86XQ2|uniprotkb:Q9UDJ6	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:ndka_human(display_long)|uniprotkb:Tumor metastatic process-associated protein(gene name synonym)|uniprotkb:Metastasis inhibition factor nm23(gene name synonym)|uniprotkb:Granzyme A-activated DNase(gene name synonym)|uniprotkb:NME1(gene name)|psi-mi:NME1(display_short)|uniprotkb:NDPKA(gene name synonym)|uniprotkb:NM23(gene name synonym)|uniprotkb:NM23-H1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11557672|imex:IM-24995-4647	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	refseq:NP_000260.1|refseq:NP_937818.1|ensembl:ENSG00000239672(gene)|ensembl:ENST00000393196(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0002762"(negative regulation of myeloid leukocyte differentiation)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004536"(deoxyribonuclease activity)|go:"GO:0004550"(nucleoside diphosphate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0006183"(GTP biosynthetic process)|go:"GO:0006228"(UTP biosynthetic process)|go:"GO:0006241"(CTP biosynthetic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007595"(lactation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014075"(response to amine)|go:"GO:0016020"(membrane)|go:"GO:0019215"(intermediate filament binding)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051591"(response to cAMP)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071398"(cellular response to fatty acid)|interpro:IPR001564(Nucleoside diphosphate kinase, core)|go:"GO:0019899"(enzyme binding)|interpro:IPR023005|go:"GO:0021766"(hippocampus development)|interpro:IPR034907|interpro:IPR036850|mint:P15531|go:"GO:0030154"(cell differentiation)|go:"GO:0032587"(ruffle membrane)|rcsb pdb:1JXV|rcsb pdb:1UCN|go:"GO:0033574"(response to testosterone)|go:"GO:0035690"|rcsb pdb:2HVD|rcsb pdb:2HVE|rcsb pdb:3L7U|rcsb pdb:4ENO|rcsb pdb:5UI4|reactome:R-HSA-499943|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043024"(ribosomal small subunit binding)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|dip:DIP-39164N|entrezgene/locuslink:4830(identity)	-	crc64:66699F37B0013088	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:Ut4gK1Xq786CaZzvqdS1eiU5op89606	intact-crc:808D14876F56CE6C|rigid:An9Y00CWrtenqHtdvGrjdLIdIfk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P12268	uniprotkb:P38340	intact:EBI-353389|uniprotkb:Q6LEF3|ensembl:ENSP00000321584	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:imdh2_human(display_long)|uniprotkb:IMPDH2(gene name)|psi-mi:IMPDH2(display_short)|uniprotkb:IMPD2(gene name synonym)|uniprotkb:Inosine-5'-monophosphate dehydrogenase type II(gene name synonym)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11557663|imex:IM-24995-4646	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000875.2|ensembl:ENSG00000178035(gene)|ensembl:ENST00000326739(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003938"(IMP dehydrogenase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006177"(GMP biosynthetic process)|go:"GO:0006183"(GTP biosynthetic process)|go:"GO:0007623"(circadian rhythm)|go:"GO:0016020"(membrane)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042802"(identical protein binding)|go:"GO:0046651"(lymphocyte proliferation)|go:"GO:0046872"(metal ion binding)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR001093(IMP dehydrogenase/GMP reductase)|interpro:IPR005990(IMP dehydrogenase)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR015875(IMP dehydrogenase / GMP reductase, conserved site)|mint:P12268|rcsb pdb:1B3O|rcsb pdb:1NF7|rcsb pdb:1NFB|rcsb pdb:6I0M|rcsb pdb:6I0O|rcsb pdb:6U8E|rcsb pdb:6U8N|rcsb pdb:6U8R|rcsb pdb:6U8S|rcsb pdb:6U9O|rcsb pdb:6UA2|rcsb pdb:6UA4|rcsb pdb:6UA5|rcsb pdb:6UAJ|rcsb pdb:6UC2|rcsb pdb:6UDO|rcsb pdb:6UDP|rcsb pdb:6UDQ|reactome:R-HSA-6798695|reactome:R-HSA-73817|reactome:R-HSA-9679191|entrezgene/locuslink:3615(identity)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	-	-	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:qGPwBxhEgtYik3OetHZbpyktoLE9606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:8133E56B1AEC850D|rigid:tdNFZkQsBnNk6qxyY9zk21jBHGA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38340	uniprotkb:P07910-2	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-5280084|ensembl:ENSP00000442816|ensembl:ENSP00000450544|ensembl:ENSP00000450725|ensembl:ENSP00000451176	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:p07910-2(display_long)|uniprotkb:HNRNPC(gene name)|psi-mi:HNRNPC(display_short)|uniprotkb:HNRPC(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11557654|imex:IM-24995-4645	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	uniprotkb:P07910-2(isoform-parent)|intact:EBI-357966(isoform-parent)|ensembl:ENSG00000092199(gene)|ensembl:ENST00000430246(transcript)|ensembl:ENST00000553300(transcript)|ensembl:ENST00000554969(transcript)|ensembl:ENST00000556897(transcript)|entrezgene/locuslink:3183(identity)	-	crc64:66699F37B0013088	isoform-comment:Contains a phosphoserine at position 107. Contains a phosphoserine at position 108.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:r7AhGozE3aHdynLr8DrXPRtOuyI9606	intact-crc:0CEC5C4466DD4D9E|rigid:/IqKzh8jrl3ECXJ1Fx+WsR4iX6M	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38159	uniprotkb:P38340	intact:EBI-743526|ensembl:ENSP00000359645|uniprotkb:Q5JQ67|uniprotkb:Q969R3|uniprotkb:D3DWH0|uniprotkb:E9PG86|uniprotkb:Q8N8Y7|uniprotkb:B4E3U4	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:rbmx_human(display_long)|uniprotkb:Glycoprotein p43(gene name synonym)|uniprotkb:RBMX(gene name)|psi-mi:RBMX(display_short)|uniprotkb:HNRPG(gene name synonym)|uniprotkb:RBMXP1(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein G(gene name synonym)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11557709|imex:IM-24995-4651	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000147274(gene)|ensembl:ENST00000320676(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000791"(euchromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0044530"(supraspliceosomal complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0006509"(membrane protein ectodomain proteolysis)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012604(RBM1CTR)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|mint:P38159|rcsb pdb:2MB0|rcsb pdb:2MKS|reactome:R-HSA-72163|reactome:R-HSA-72203|reactome:R-HSA-9013418|reactome:R-HSA-9013422|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273|refseq:NP_002130.2|refseq:NP_001158275.1|dip:DIP-34447N|entrezgene/locuslink:27316(identity)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	-	-	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:ocCkdy9PxjeVLUQf0tMVCEhFfO89606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:04D54A1949B5E01B|rigid:Lr3MO6Jzc9pvQFInXgb84MSkeJ8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38340	uniprotkb:P48775	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-743494|ensembl:ENSP00000444788|ensembl:ENSP00000460086|uniprotkb:A8K053	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:t23o_human(display_long)|uniprotkb:Tryptophan pyrrolase(gene name synonym)|uniprotkb:Tryptophan oxygenase(gene name synonym)|uniprotkb:Tryptamin 2,3-dioxygenase(gene name synonym)|uniprotkb:TDO2(gene name)|psi-mi:TDO2(display_short)|uniprotkb:TDO(gene name synonym)|uniprotkb:Tryptophanase(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11557736|imex:IM-24995-4654	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	ensembl:ENSG00000151790(gene)|ensembl:ENSG00000262635(gene)|ensembl:ENST00000536354(transcript)|ensembl:ENST00000573403(transcript)|go:"GO:0004833"(tryptophan 2,3-dioxygenase activity)|go:"GO:0005829"(cytosol)|go:"GO:0016597"(amino acid binding)|go:"GO:0019441"(tryptophan catabolic process to kynurenine)|go:"GO:0019442"(tryptophan catabolic process to acetyl-CoA)|go:"GO:0019825"(oxygen binding)|go:"GO:0020037"(heme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051289"(protein homotetramerization)|go:"GO:1904842"(response to nitroglycerin)|interpro:IPR004981(Tryptophan 2,3-dioxygenase)|interpro:IPR037217|mint:P48775|rcsb pdb:4PW8|rcsb pdb:5TI9|rcsb pdb:5TIA|rcsb pdb:6A4I|rcsb pdb:6PYY|rcsb pdb:6PYZ|rcsb pdb:6UD5|rcsb pdb:6VBN|reactome:R-HSA-71240|refseq:NP_005642.1|entrezgene/locuslink:6999(identity)	-	crc64:66699F37B0013088	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:S+cyc710I52nIFQWgKhXFul9QZw9606	intact-crc:29AA6D423AD3BE97|rigid:0jJMO8ij0i4soToT9UC7lpFwQVI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38340	uniprotkb:P38646	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-354932|ensembl:ENSP00000297185|uniprotkb:P30036|uniprotkb:P31932|uniprotkb:Q6GU03|uniprotkb:Q9BWB7|uniprotkb:B2RCM1|uniprotkb:Q1HB43|uniprotkb:Q53H23|uniprotkb:Q9UC56	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:grp75_human(display_long)|uniprotkb:HSPA9(gene name)|psi-mi:HSPA9(display_short)|uniprotkb:GRP75(gene name synonym)|uniprotkb:HSPA9B(gene name synonym)|uniprotkb:75 kDa glucose-regulated protein(gene name synonym)|uniprotkb:Heat shock 70 kDa protein 9(gene name synonym)|uniprotkb:Peptide-binding protein 74(gene name synonym)|uniprotkb:Mortalin(gene name synonym)|uniprotkb:mt-HSP70(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11557727|imex:IM-24995-4653	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	reactome:R-HSA-8949613|reactome:R-HSA-8950505|ensembl:ENSG00000113013(gene)|ensembl:ENST00000297185(transcript)|go:"GO:0001401"(SAM complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005925"(focal adhesion)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0007007"(inner mitochondrial membrane organization)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045646"(regulation of erythrocyte differentiation)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0140275"(MIB complex)|go:"GO:1902037"(negative regulation of hematopoietic stem cell differentiation)|go:"GO:1903707"(negative regulation of hemopoiesis)|interpro:IPR012725(Chaperone DnaK)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|go:"GO:0070062"(extracellular exosome)|interpro:IPR043129|mint:P38646|rcsb pdb:3N8E|rcsb pdb:4KBO|rcsb pdb:6NHK|rcsb pdb:6P2U|rcsb pdb:6PMT|reactome:R-HSA-1268020|reactome:R-HSA-3371453|refseq:NP_004125.3|dip:DIP-32936N|entrezgene/locuslink:3313(identity)	-	crc64:66699F37B0013088	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:xjSHeTKBb/lH1XNEEiMIjsM+XcE9606	intact-crc:76FC5C00DAB04910|rigid:pM5gDg0qNFxvRHzy6g57D7kSfCw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38340	uniprotkb:P38432	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-945751|uniprotkb:B2R931|ensembl:ENSP00000240316	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:coil_human(display_long)|uniprotkb:COIL(gene name)|psi-mi:COIL(display_short)|uniprotkb:CLN80(gene name synonym)|uniprotkb:p80-coilin(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11557718|imex:IM-24995-4652	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	refseq:NP_004636.1|dip:DIP-38503N|ensembl:ENSG00000121058(gene)|ensembl:ENST00000240316(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0015030"(Cajal body)|go:"GO:0016020"(membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0030619"(U1 snRNA binding)|go:"GO:0030620"(U2 snRNA binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR024822|interpro:IPR031722|mint:P38432|entrezgene/locuslink:8161(identity)	-	crc64:66699F37B0013088	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:hd5p6AbyA/GYNEeca99Mdb41qM09606	intact-crc:7A5381BFB5D65737|rigid:LampXM0o/TLDnA7/30h35Wyu4V4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49247	uniprotkb:P38340	intact:EBI-744831|uniprotkb:Q541P9|uniprotkb:Q96BJ6|ensembl:ENSP00000283646	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:rpia_human(display_long)|uniprotkb:Phosphoriboisomerase(gene name synonym)|uniprotkb:RPIA(gene name)|psi-mi:RPIA(display_short)|uniprotkb:RPI(gene name synonym)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11557745|imex:IM-24995-4655	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_653164.2|ensembl:ENSG00000153574(gene)|ensembl:ENST00000283646(transcript)|go:"GO:0004751"(ribose-5-phosphate isomerase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006014"(D-ribose metabolic process)|go:"GO:0006098"(pentose-phosphate shunt)|go:"GO:0009052"(pentose-phosphate shunt, non-oxidative branch)|go:"GO:0019693"(ribose phosphate metabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048029"(monosaccharide binding)|interpro:IPR004788(Ribose 5-phosphate isomerase)|interpro:IPR020672|interpro:IPR037171|mint:P49247|reactome:R-HSA-5659996|reactome:R-HSA-6791461|reactome:R-HSA-71336|entrezgene/locuslink:22934(identity)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	-	-	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:gddu0Xp/dx4JwbFMs50pQCvvbws9606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:BF8C48B67EC5E619|rigid:N5V4GvqknWvyrUhzlVV65DEhyfw	false	sufficient binding region:75-311	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P61289	uniprotkb:P38340	intact:EBI-355546|uniprotkb:O35563|uniprotkb:P97373|uniprotkb:Q12920|uniprotkb:Q13172|uniprotkb:Q9BQD9|uniprotkb:A8K9A3|ensembl:ENSP00000466794	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:psme3_human(display_long)|uniprotkb:PSME3(gene name)|psi-mi:PSME3(display_short)|uniprotkb:Proteasome activator 28 subunit gamma(gene name synonym)|uniprotkb:Activator of multicatalytic protease subunit 3(gene name synonym)|uniprotkb:11S regulator complex subunit gamma(gene name synonym)|uniprotkb:Ki nuclear autoantigen(gene name synonym)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11557775|imex:IM-24995-4658	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005780.2|refseq:NP_789839.1|ensembl:ENSG00000131467(gene)|ensembl:ENST00000590720(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0008537"(proteasome activator complex)|go:"GO:0010950"(positive regulation of endopeptidase activity)|go:"GO:0016020"(membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0061133"(endopeptidase activator activity)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0097371"(MDM2/MDM4 family protein binding)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR003185(Proteasome activator pa28, REG alpha subunit)|interpro:IPR003186(Proteasome activator pa28, REG beta subunit)|interpro:IPR009077(Proteasome activator pa28, REG alpha/beta subunit)|interpro:IPR036252|interpro:IPR036996|interpro:IPR036997|mint:P61289|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|entrezgene/locuslink:10197(identity)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	-	-	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:6EQY2Kj3Juf++m4eBDzPWMgbC2k9606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:E92617C3250697F0|rigid:7U4wu5I6Bsc+tS2OG9Fyn5XNSG8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38340	uniprotkb:P62333	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-357669|uniprotkb:Q92524|uniprotkb:P49719|uniprotkb:Q6IBU3|uniprotkb:B2R975|ensembl:ENSP00000401802	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:prs10_human(display_long)|uniprotkb:PSMC6(gene name)|psi-mi:PSMC6(display_short)|uniprotkb:SUG2(gene name synonym)|uniprotkb:Proteasome 26S subunit ATPase 6(gene name synonym)|uniprotkb:Proteasome subunit p42(gene name synonym)|uniprotkb:26S proteasome AAA-ATPase subunit RPT4(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11557784|imex:IM-24995-4659	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	refseq:NP_002797.3|ensembl:ENST00000445930(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|ensembl:ENSG00000100519(gene)|go:"GO:0005829"(cytosol)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0016234"(inclusion body)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0042802"(identical protein binding)|interpro:IPR032501|interpro:IPR035263|interpro:IPR041569|mint:P62333|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHJ|rcsb pdb:5VHM|rcsb pdb:5VHN|rcsb pdb:5VHO|rcsb pdb:5VHP|rcsb pdb:5VHQ|rcsb pdb:5VHR|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090261"(positive regulation of inclusion body assembly)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-75815|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-174184|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|dip:DIP-38150N|entrezgene/locuslink:5706(identity)	-	crc64:66699F37B0013088	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:QE8jzSEp1bpzhOi/oAAnV18QK249606	intact-crc:4EEA4233F399D494|rigid:pDcOS7AIb75qNpuh4qYhVztcmHI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P63261	uniprotkb:P38340	intact:EBI-351292|uniprotkb:P02571|uniprotkb:P14104|uniprotkb:P99022|uniprotkb:Q5U032|uniprotkb:Q96E67|uniprotkb:A8K7C2|ensembl:ENSP00000505060|ensembl:ENSP00000505193|ensembl:ENSP00000505235|ensembl:ENSP00000506126|ensembl:ENSP00000506201|ensembl:ENSP00000506253|ensembl:ENSP00000458162|ensembl:ENSP00000458435|ensembl:ENSP00000459119|ensembl:ENSP00000459124|ensembl:ENSP00000460464|ensembl:ENSP00000460660|ensembl:ENSP00000461672|ensembl:ENSP00000466346|ensembl:ENSP00000477968	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:actg_human(display_long)|uniprotkb:ACTG1(gene name)|psi-mi:ACTG1(display_short)|uniprotkb:ACTG(gene name synonym)|uniprotkb:Gamma-actin(gene name synonym)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11557793|imex:IM-24995-4660	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001186883.1|refseq:NP_001605.1|ensembl:ENST00000570382(transcript)|ensembl:ENSG00000184009(gene)|ensembl:ENST00000571721(transcript)|ensembl:ENST00000573283(transcript)|ensembl:ENST00000575087(transcript)|ensembl:ENST00000575659(transcript)|ensembl:ENST00000575842(transcript)|ensembl:ENST00000575994(transcript)|ensembl:ENST00000576544(transcript)|ensembl:ENST00000615544(transcript)|ensembl:ENST00000679480(transcript)|ensembl:ENST00000679778(transcript)|ensembl:ENST00000680227(transcript)|ensembl:ENST00000680727(transcript)|ensembl:ENST00000681052(transcript)|ensembl:ENST00000681842(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0001895"(retina homeostasis)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005522"(profilin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0030016"(myofibril)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031941"(filamentous actin)|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0044305"(calyx of Held)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0051492"(regulation of stress fiber assembly)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070527"(platelet aggregation)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0072562"(blood microparticle)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0097433"(dense body)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098973"(structural constituent of postsynaptic actin cytoskeleton)|go:"GO:0120192"(tight junction assembly)|go:"GO:0120220"(basal body patch)|go:"GO:0150111"(regulation of transepithelial transport)|go:"GO:1902396"(protein localization to bicellular tight junction)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P63261|rcsb pdb:5JLH|rcsb pdb:6CXI|rcsb pdb:6CXJ|rcsb pdb:6G2T|rcsb pdb:6V62|rcsb pdb:6V63|rcsb pdb:6WK1|rcsb pdb:6WK2|reactome:R-HSA-1445148|reactome:R-HSA-190873|reactome:R-HSA-196025|reactome:R-HSA-2029482|reactome:R-HSA-3928662|reactome:R-HSA-3928665|reactome:R-HSA-418990|reactome:R-HSA-437239|reactome:R-HSA-4420097|reactome:R-HSA-445095|reactome:R-HSA-446353|reactome:R-HSA-5626467|reactome:R-HSA-5663213|reactome:R-HSA-5663220|reactome:R-HSA-5674135|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8856828|reactome:R-HSA-9013418|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9662360|reactome:R-HSA-9662361|reactome:R-HSA-9664422|entrezgene/locuslink:71(identity)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	-	-	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:B2OOsE06lTfo90H3g8tlmUJQ7cY9606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:3C5D4DAF0C4B0C5E|rigid:MnDFBVJYjyHANBw0C0Mv5JYfEM0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P60891	uniprotkb:P38340	intact:EBI-749195|uniprotkb:P09329|uniprotkb:B2R6T7|uniprotkb:B1ALA8|uniprotkb:B4DNL6|uniprotkb:D3DUX6|ensembl:ENSP00000361512	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:prps1_human(display_long)|uniprotkb:Phosphoribosyl pyrophosphate synthase I(gene name synonym)|uniprotkb:PRPS1(gene name)|psi-mi:PRPS1(display_short)|uniprotkb:PPRibP(gene name synonym)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11557766|imex:IM-24995-4657	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001191331.1|refseq:NP_002755.1|ensembl:ENSG00000147224(gene)|ensembl:ENST00000372435(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0002189"(ribose phosphate diphosphokinase complex)|go:"GO:0004749"(ribose phosphate diphosphokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006015"(5-phosphoribose 1-diphosphate biosynthetic process)|go:"GO:0006164"(purine nucleotide biosynthetic process)|go:"GO:0006221"(pyrimidine nucleotide biosynthetic process)|go:"GO:0007399"(nervous system development)|go:"GO:0009116"(nucleoside metabolic process)|go:"GO:0009156"(ribonucleoside monophosphate biosynthetic process)|go:"GO:0016301"(kinase activity)|go:"GO:0034418"(urate biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046101"(hypoxanthine biosynthetic process)|interpro:IPR000836(Phosphoribosyltransferase)|interpro:IPR000842(Phosphoribosyl pyrophosphate synthetase, conserved site)|interpro:IPR005946(Phosphoribosyl pyrophosphokinase)|go:"GO:0006144"(purine nucleobase metabolic process)|interpro:IPR029057|interpro:IPR029099|interpro:IPR037515|rcsb pdb:2H06|rcsb pdb:2H07|rcsb pdb:2H08|rcsb pdb:2HCR|rcsb pdb:3EFH|rcsb pdb:3S5J|rcsb pdb:4F8E|rcsb pdb:4LYG|rcsb pdb:4LZN|rcsb pdb:4LZO|rcsb pdb:4M0P|rcsb pdb:4M0U|reactome:R-HSA-73843|dip:DIP-61999N|entrezgene/locuslink:5631(identity)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	-	-	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:+Hih2M7JLTsjEglauBlPj182h9M9606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:9176B827CC929B80|rigid:EEjOnv8wbKDeIzNK2fZ28hS+xLw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P60709	uniprotkb:P38340	intact:EBI-353944|uniprotkb:P02570|uniprotkb:P70514|uniprotkb:P99021|uniprotkb:Q11211|uniprotkb:Q64316|uniprotkb:Q75MN2|uniprotkb:Q96B34|uniprotkb:Q96HG5|ensembl:ENSP00000494269|ensembl:ENSP00000494750|ensembl:ENSP00000495995|ensembl:ENSP00000501862|ensembl:ENSP00000502821	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:actb_human(display_long)|uniprotkb:ACTB(gene name)|psi-mi:ACTB(display_short)|uniprotkb:Beta-actin(gene name synonym)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11557756|imex:IM-24995-4656	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001092.1|ensembl:ENSG00000075624(gene)|ensembl:ENST00000493945(transcript)|ensembl:ENST00000642480(transcript)|ensembl:ENST00000646664(transcript)|ensembl:ENST00000674681(transcript)|ensembl:ENST00000675515(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000785"(chromatin)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0001895"(retina homeostasis)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007409"(axonogenesis)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019894"(kinesin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0022898"(regulation of transmembrane transporter activity)|go:"GO:0030027"(lamellipodium)|go:"GO:0030424"(axon)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0030957"(Tat protein binding)|go:"GO:0031982"(vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034333"(adherens junction assembly)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043044"|go:"GO:0043296"(apical junction complex)|go:"GO:0044305"(calyx of Held)|go:"GO:0045176"(apical protein localization)|go:"GO:0045202"(synapse)|go:"GO:0048156"(tau protein binding)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048870"(cell motility)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051621"(regulation of norepinephrine uptake)|go:"GO:0051623"(positive regulation of norepinephrine uptake)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070160"(tight junction)|go:"GO:0070527"(platelet aggregation)|reactome:R-HSA-4420097|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0072562"(blood microparticle)|go:"GO:0072749"(cellular response to cytochalasin B)|go:"GO:0097433"(dense body)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098973"(structural constituent of postsynaptic actin cytoskeleton)|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0150111"(regulation of transepithelial transport)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P60709|rcsb pdb:3BYH|rcsb pdb:3D2U|rcsb pdb:3J82|rcsb pdb:3LUE|rcsb pdb:6ANU|rcsb pdb:6ICT|rcsb pdb:6ICV|rcsb pdb:6LTJ|rcsb pdb:6MBJ|rcsb pdb:6MBK|rcsb pdb:6MBL|rcsb pdb:6NBW|rcsb pdb:6OX0|rcsb pdb:6OX1|rcsb pdb:6OX2|rcsb pdb:6OX3|rcsb pdb:6OX4|rcsb pdb:6OX5|rcsb pdb:6V62|rcsb pdb:6V63|rcsb pdb:6WK1|rcsb pdb:6WK2|rcsb pdb:7AS4|reactome:R-HSA-1445148|reactome:R-HSA-190873|reactome:R-HSA-196025|reactome:R-HSA-2029482|reactome:R-HSA-3214847|reactome:R-HSA-389957|reactome:R-HSA-390450|reactome:R-HSA-3928662|reactome:R-HSA-3928665|reactome:R-HSA-418990|reactome:R-HSA-437239|reactome:R-HSA-446353|reactome:R-HSA-5250924|reactome:R-HSA-5626467|reactome:R-HSA-5663213|reactome:R-HSA-5663220|reactome:R-HSA-5674135|reactome:R-HSA-5689603|reactome:R-HSA-5696394|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8856828|reactome:R-HSA-9035034|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9662360|reactome:R-HSA-9662361|reactome:R-HSA-9664422|reactome:R-HSA-983231|reactome:R-HSA-445095|dip:DIP-29686N|entrezgene/locuslink:60(identity)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	-	-	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Hoge1B8Pn56kvbNTpkSLsQuHwRc9606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:F6EC98EF485A337D|rigid:dOsk2RtACj0gTuWtoa2+2MORKdE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38340	uniprotkb:P98170	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-517127|uniprotkb:Q9NQ14|uniprotkb:D3DTF2|ensembl:ENSP00000347858|ensembl:ENSP00000360242|ensembl:ENSP00000395230	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:xiap_human(display_long)|uniprotkb:Inhibitor of apoptosis protein 3(gene name synonym)|uniprotkb:X-linked inhibitor of apoptosis protein(gene name synonym)|uniprotkb:IAP-like protein(gene name synonym)|uniprotkb:XIAP(gene name)|psi-mi:XIAP(display_short)|uniprotkb:API3(gene name synonym)|uniprotkb:IAP3(gene name synonym)|uniprotkb:BIRC4(gene name synonym)|uniprotkb:Baculoviral IAP repeat-containing protein 4(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase XIAP(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11557812|imex:IM-24995-4662	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	refseq:XP_006724817.1|refseq:NP_001158.2|refseq:NP_001191330.1|refseq:XP_011529631.1|dip:DIP-27626N|ensembl:ENSG00000101966(gene)|ensembl:ENST00000355640(transcript)|ensembl:ENST00000371199(transcript)|ensembl:ENST00000434753(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005876"(spindle microtubule)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030510"(regulation of BMP signaling pathway)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0055070"(copper ion homeostasis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070424"(regulation of nucleotide-binding oligomerization domain containing signaling pathway)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:1902530"(positive regulation of protein linear polyubiquitination)|go:"GO:1990001"(inhibition of cysteine-type endopeptidase activity involved in apoptotic process)|interpro:IPR001370(Proteinase inhibitor I32, inhibitor of apoptosis)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011029(DEATH-like)|interpro:IPR042579|mint:P98170|rcsb pdb:1C9Q|rcsb pdb:1F9X|rcsb pdb:1G3F|rcsb pdb:1G73|rcsb pdb:1I3O|rcsb pdb:1I4O|rcsb pdb:1I51|rcsb pdb:1KMC|rcsb pdb:1NW9|rcsb pdb:1TFQ|rcsb pdb:1TFT|rcsb pdb:2ECG|rcsb pdb:2JK7|rcsb pdb:2KNA|rcsb pdb:2OPY|rcsb pdb:2OPZ|rcsb pdb:2POI|rcsb pdb:2POP|rcsb pdb:2QRA|rcsb pdb:2VSL|rcsb pdb:3CLX|rcsb pdb:3CM2|rcsb pdb:3CM7|rcsb pdb:3EYL|rcsb pdb:3G76|rcsb pdb:3HL5|rcsb pdb:3UW4|rcsb pdb:3UW5|rcsb pdb:4EC4|rcsb pdb:4HY0|rcsb pdb:4IC2|rcsb pdb:4IC3|rcsb pdb:4J3Y|rcsb pdb:4J44|rcsb pdb:4J45|rcsb pdb:4J46|rcsb pdb:4J47|rcsb pdb:4J48|rcsb pdb:4KJU|rcsb pdb:4KJV|rcsb pdb:4KMP|rcsb pdb:4MTZ|rcsb pdb:4OXC|rcsb pdb:4WVS|rcsb pdb:4WVT|rcsb pdb:4WVU|rcsb pdb:5C0K|rcsb pdb:5C0L|rcsb pdb:5C3H|rcsb pdb:5C3K|rcsb pdb:5C7A|rcsb pdb:5C7B|rcsb pdb:5C7C|rcsb pdb:5C7D|rcsb pdb:5C83|rcsb pdb:5C84|rcsb pdb:5M6E|rcsb pdb:5M6F|rcsb pdb:5M6H|rcsb pdb:5M6L|rcsb pdb:5M6M|rcsb pdb:5O6T|rcsb pdb:5OQW|rcsb pdb:6EY2|rcsb pdb:6GJW|rcsb pdb:6QCI|reactome:R-HSA-111459|reactome:R-HSA-111463|reactome:R-HSA-111464|reactome:R-HSA-111469|reactome:R-HSA-3769402|reactome:R-HSA-5213460|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5675482|reactome:R-HSA-8948747|reactome:R-HSA-8948751|reactome:R-HSA-9627069|entrezgene/locuslink:331(identity)	-	crc64:66699F37B0013088	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:6eDcOay+c2ZmIAD/pwnCDROBwgM9606	intact-crc:C50BE99AE75834FD|rigid:hKpSWqBZNFklBmgvmQu7TjwTT2Y	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38340	uniprotkb:Q03393	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-712344|ensembl:ENSP00000280362|uniprotkb:Q8WVG8|uniprotkb:B0YJ87	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:ptps_human(display_long)|uniprotkb:PTS(gene name)|psi-mi:PTS(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11557821|imex:IM-24995-4663	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	refseq:NP_000308.1|ensembl:ENSG00000150787(gene)|ensembl:ENST00000280362(transcript)|go:"GO:0003874"(6-pyruvoyltetrahydropterin synthase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006520"(cellular amino acid metabolic process)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0007417"(central nervous system development)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR007115(6-pyruvoyl tetrahydropterin synthase-related)|interpro:IPR022469|interpro:IPR022470|interpro:IPR038418|rcsb pdb:3I2B|reactome:R-HSA-1474151|entrezgene/locuslink:5805(identity)	-	crc64:66699F37B0013088	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:Qa3bMpzyvRxrvDq9dZUSQlfbpeg9606	intact-crc:25653C7662206A1E|rigid:/B45h0c5qBVDxEyJmefaim2Nfjw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12800	uniprotkb:P38340	intact:EBI-717422|uniprotkb:Q12801|uniprotkb:Q9UD77|uniprotkb:A8K5E9|uniprotkb:Q9UD75|ensembl:ENSP00000257915	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:tfcp2_human(display_long)|uniprotkb:Transcription factor LSF(gene name synonym)|uniprotkb:SAA3 enhancer factor(gene name synonym)|uniprotkb:TFCP2(gene name)|psi-mi:TFCP2(display_short)|uniprotkb:LSF(gene name synonym)|uniprotkb:SEF(gene name synonym)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11557831|imex:IM-24995-4664	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001166923.1|refseq:NP_001166924.1|refseq:NP_005644.2|ensembl:ENSG00000135457(gene)|ensembl:ENST00000257915(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR007604(CP2 transcription factor)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR037599|interpro:IPR041418|mint:Q12800|entrezgene/locuslink:7024(identity)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	-	-	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:M7mQ08NDYxuawmUEKRgjSdIr+Og9606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:A02838A56BDFF926|rigid:yH67WZVVVPUmvnYbu6oMf54oRps	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38340	uniprotkb:Q13049	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-742790|ensembl:ENSP00000363095|ensembl:ENSP00000408292|uniprotkb:Q9NQP8	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:tri32_human(display_long)|uniprotkb:Zinc finger protein HT2A(gene name synonym)|uniprotkb:72 kDa Tat-interacting protein(gene name synonym)|uniprotkb:TRIM32(gene name)|psi-mi:TRIM32(display_short)|uniprotkb:HT2A(gene name synonym)|uniprotkb:Tripartite motif-containing protein 32(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM32(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11557840|imex:IM-24995-4665	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	go:"GO:0043621"(protein self-association)|go:"GO:0045087"(innate immune response)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051155"(positive regulation of striated muscle cell differentiation)|go:"GO:0061564"(axon development)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1902187"|go:"GO:1902230"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:1903265"(positive regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:1903883"(positive regulation of interleukin-17-mediated signaling pathway)|go:"GO:1903886"("positive regulation of chemokine (C-C motif) ligand 20 production")|go:"GO:2000147"(positive regulation of cell motility)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENSG00000119401(gene)|ensembl:ENST00000373983(transcript)|ensembl:ENST00000450136(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001894"(tissue homeostasis)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005863"(striated muscle myosin thick filament)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007014"(actin ubiquitination)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009411"(response to UV)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0017022"(myosin binding)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030957"(Tat protein binding)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034612"(response to tumor necrosis factor)|go:"GO:0042802"(identical protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|interpro:IPR000315(Zinc finger, B-box)|refseq:NP_001093149.1|refseq:XP_011516700.1|refseq:NP_036342.2|refseq:XP_005251870.1|interpro:IPR001258(NHL repeat)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR013017(NHL repeat, subgroup)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR027370|mint:Q13049|rcsb pdb:2CT2|rcsb pdb:5FEY|reactome:R-HSA-3134975|reactome:R-HSA-983168|refseq:XP_016869975.1|entrezgene/locuslink:22954(identity)	-	crc64:66699F37B0013088	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:XuqprQd10kSpsuyGs+FSdzIdJ/Y9606	intact-crc:3B42B322DE61A110|rigid:wrjCZrkmckE2GdnFZY8FI/59o0U	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38340	uniprotkb:Q13155	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-745226|uniprotkb:Q75MR1|uniprotkb:Q96CZ5|uniprotkb:Q9P1L2|ensembl:ENSP00000223029|uniprotkb:F8W950	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:aimp2_human(display_long)|uniprotkb:Protein JTV-1(gene name synonym)|uniprotkb:AIMP2(gene name)|psi-mi:AIMP2(display_short)|uniprotkb:PRO0992(orf name)|uniprotkb:JTV1(gene name synonym)|uniprotkb:Multisynthase complex auxiliary component p38(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11557849|imex:IM-24995-4666	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	refseq:NP_006294.2|ensembl:ENSG00000106305(gene)|ensembl:ENST00000223029(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0006915"(apoptotic process)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0017101"(aminoacyl-tRNA synthetase multienzyme complex)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060510"(type II pneumocyte differentiation)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1903632"(positive regulation of aminoacyl-tRNA ligase activity)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR031889|interpro:IPR036282|interpro:IPR041503|interpro:IPR042360|mint:Q13155|rcsb pdb:4DPG|rcsb pdb:4YCU|rcsb pdb:4YCW|rcsb pdb:5A1N|rcsb pdb:5A34|rcsb pdb:5A5H|rcsb pdb:5Y6L|rcsb pdb:6ILD|rcsb pdb:6IY6|rcsb pdb:6JPV|rcsb pdb:6K39|reactome:R-HSA-2408522|reactome:R-HSA-379716|dip:DIP-34421N|refseq:NP_001313536.1|entrezgene/locuslink:7965(identity)	-	crc64:66699F37B0013088	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:VEBmJjo6t3dBY6mKpmUyVLamJFQ9606	intact-crc:BC3C97462AC93483|rigid:jR+RbnhnSRFmhMPqtcFqWwRSkMw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P63279	uniprotkb:P38340	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11557803|imex:IM-24995-4661	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N|entrezgene/locuslink:7329(identity)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	-	-	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:A1C28C6929BEACF6|rigid:yPWLvTo5VQGN2yAOaM1tPNCnHvg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q13867	uniprotkb:P38340	intact:EBI-718504|uniprotkb:Q53F86|uniprotkb:Q9UER9|uniprotkb:B2R796|ensembl:ENSP00000261714	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:blmh_human(display_long)|uniprotkb:BLMH(gene name)|psi-mi:BLMH(display_short)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11557859|imex:IM-24995-4667	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000377.1|ensembl:ENSG00000108578(gene)|ensembl:ENST00000261714(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004177"(aminopeptidase activity)|go:"GO:0004180"(carboxypeptidase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006508"(proteolysis)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0009636"(response to toxic substance)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043418"(homocysteine catabolic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000169(Peptidase, cysteine peptidase active site)|interpro:IPR004134(Peptidase C1B, bleomycin hydrolase)|interpro:IPR038765|mint:Q13867|rcsb pdb:1CB5|rcsb pdb:2CB5|reactome:R-HSA-983168|entrezgene/locuslink:642(identity)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	-	-	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:THDv63DC81eQzFvmyWs1rlCBMyk9606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:C4225C6B60CCBE62|rigid:yUwNVOPo80ORo/HA36C+4GlHasM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38340	uniprotkb:Q14749	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-744239|uniprotkb:Q9NNZ1|uniprotkb:Q9NS24|uniprotkb:Q5T8W2|ensembl:ENSP00000361894	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:gnmt_human(display_long)|uniprotkb:GNMT(gene name)|psi-mi:GNMT(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11557868|imex:IM-24995-4668	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	refseq:NP_061833.1|refseq:NP_001305794.1|ensembl:ENSG00000124713(gene)|ensembl:ENST00000372808(transcript)|go:"GO:0005542"(folic acid binding)|go:"GO:0005829"(cytosol)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0006111"(regulation of gluconeogenesis)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006555"(methionine metabolic process)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0016594"(glycine binding)|go:"GO:0017174"(glycine N-methyltransferase activity)|go:"GO:0032259"(methylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0046498"(S-adenosylhomocysteine metabolic process)|go:"GO:0046500"(S-adenosylmethionine metabolic process)|go:"GO:0051289"(protein homotetramerization)|go:"GO:1901052"(sarcosine metabolic process)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|interpro:IPR014369(Glycine N-methyltransferase)|interpro:IPR029063|interpro:IPR041698|rcsb pdb:1R74|rcsb pdb:2AZT|reactome:R-HSA-2408508|reactome:R-HSA-389661|entrezgene/locuslink:27232(identity)	-	crc64:66699F37B0013088	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:noj0nCgjJ1Dq079ycrwAu30a4AU9606	intact-crc:467AA463BC2BE60E|rigid:c92KjjiBa0Gz8YncPU5yIUfJv7M	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q15025	uniprotkb:P38340	intact:EBI-357849|uniprotkb:A4F1W8|uniprotkb:O76008|uniprotkb:Q96EL9|uniprotkb:Q99833|uniprotkb:Q9H1J3|uniprotkb:B7Z699|uniprotkb:Q6N077|ensembl:ENSP00000317891|ensembl:ENSP00000428187|ensembl:ENSP00000430760|uniprotkb:A4F1W9|uniprotkb:A4F1X2|uniprotkb:A4F1X4|uniprotkb:A4F1X5|uniprotkb:A4F1X6|uniprotkb:A4F1X7|uniprotkb:A4F1X9|uniprotkb:E7EPY1|uniprotkb:E7ET96|uniprotkb:Q05KP3|uniprotkb:Q05KP4	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:tnip1_human(display_long)|uniprotkb:TNIP1(gene name)|psi-mi:TNIP1(display_short)|uniprotkb:KIAA0113(gene name synonym)|uniprotkb:NAF1(gene name synonym)|uniprotkb:Nef-associated factor 1(gene name synonym)|uniprotkb:HIV-1 Nef-interacting protein(gene name synonym)|uniprotkb:Virion-associated nuclear shuttling protein(gene name synonym)|uniprotkb:Nip40-1(gene name synonym)|uniprotkb:A20-binding inhibitor of NF-kappa-B activation 1(gene name synonym)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11557877|imex:IM-24995-4669	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006049.3|refseq:NP_001239319.1|refseq:NP_001239320.1|refseq:NP_001239321.1|refseq:NP_001239322.1|refseq:NP_001245383.1|dip:DIP-27577N|refseq:NP_001239315.1|ensembl:ENSG00000145901(gene)|ensembl:ENST00000315050(transcript)|ensembl:ENST00000521591(transcript)|ensembl:ENST00000522226(transcript)|go:"GO:0002755"(MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0006952"(defense response)|go:"GO:0006954"(inflammatory response)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0009101"(glycoprotein biosynthetic process)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0085032"(modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade)|go:"GO:1903003"(positive regulation of protein deubiquitination)|interpro:IPR033372|mint:Q15025|reactome:R-HSA-5689896|go:"GO:0051019"(mitogen-activated protein kinase binding)|refseq:NP_001239314.1|refseq:NP_001245384.1|refseq:NP_001245385.1|refseq:XP_006714814.1|refseq:XP_006714815.1|entrezgene/locuslink:10318(identity)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	-	-	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:16Vjb5CuGTAbW2M22qbCxgXtV1o9606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:F51989D1FD78FE63|rigid:SBHyqjq5wE+LbLMQbXVnKqxweoo	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38340	uniprotkb:Q15038	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-724310|ensembl:ENSP00000394699|uniprotkb:E9PB45|uniprotkb:A8K254|uniprotkb:B4DDT5|uniprotkb:C9JA96|uniprotkb:C9JP84|uniprotkb:B4E1G3|uniprotkb:F8VU62	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:dazp2_human(display_long)|uniprotkb:Deleted in azoospermia-associated protein 2(gene name synonym)|uniprotkb:DAZAP2(gene name)|psi-mi:DAZAP2(display_short)|uniprotkb:KIAA0058(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11557887|imex:IM-24995-4670	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	ensembl:ENSG00000183283(gene)|ensembl:ENST00000412716(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0016607"(nuclear speck)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0050699"(WW domain binding)|interpro:IPR022730|mint:Q15038|refseq:NP_001129736.1|refseq:NP_055579.1|ensembl:ENSP00000394699|ensembl:ENST00000425012|ensembl:ENSP00000408251|ensembl:ENST00000439799|ensembl:ENSP00000398804|ensembl:ENST00000449723|ensembl:ENSP00000412812|ensembl:ENST00000549555|ensembl:ENSP00000448051|ensembl:ENST00000549732|ensembl:ENSP00000446554|refseq:NP_001129741.1|refseq:NP_001129739.1|refseq:NP_001129740.1|refseq:NP_001129738.1|entrezgene/locuslink:9802(identity)	-	crc64:66699F37B0013088	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:ASRqCZBG4q1U/y95PUSMKsgfm/g9606	intact-crc:CFD1104809D436A7|rigid:tWYfZtkHuwaAtyHJIKpEo2Z9YTY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q16637	uniprotkb:P38340	intact:EBI-395421|uniprotkb:Q13119|uniprotkb:Q549U5|uniprotkb:Q96J51|ensembl:ENSP00000305857|uniprotkb:A8K0V4|ensembl:ENSP00000370083|ensembl:ENSP00000370117|ensembl:ENSP00000370119|ensembl:ENSP00000479920|ensembl:ENSP00000482966|ensembl:ENSP00000483515|ensembl:ENSP00000483819|ensembl:ENSP00000487206|ensembl:ENSP00000487421	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:smn_human(display_long)|uniprotkb:SMN1(gene name)|psi-mi:SMN1(display_short)|uniprotkb:SMN(gene name synonym)|uniprotkb:SMNT(gene name synonym)|uniprotkb:SMN2(gene name)|psi-mi:SMN2(display_short)|uniprotkb:SMNC(gene name synonym)|uniprotkb:Component of gems 1(gene name synonym)|uniprotkb:Gemin-1(gene name synonym)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11557914|imex:IM-24995-4673	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000335.1|refseq:NP_059107.1|refseq:NP_075012.1|refseq:NP_075013.1|refseq:NP_075014.1|refseq:NP_075015.1|ensembl:ENSG00000172062(gene)|ensembl:ENSG00000205571(gene)|ensembl:ENSG00000273772(gene)|ensembl:ENSG00000275349(gene)|ensembl:ENSG00000277773(gene)|ensembl:ENST00000351205(transcript)|ensembl:ENST00000380707(transcript)|ensembl:ENST00000380741(transcript)|ensembl:ENST00000380743(transcript)|ensembl:ENST00000614610(transcript)|ensembl:ENST00000618251(transcript)|ensembl:ENST00000618661(transcript)|ensembl:ENST00000622739(transcript)|ensembl:ENST00000627341(transcript)|ensembl:ENST00000629122(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0007399"(nervous system development)|go:"GO:0015030"(Cajal body)|go:"GO:0016604"(nuclear body)|go:"GO:0030018"(Z disc)|go:"GO:0030424"(axon)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043204"(perikaryon)|go:"GO:0097504"(Gemini of coiled bodies)|interpro:IPR002999(Tudor)|interpro:IPR010304(Survival motor neuron)|mint:Q16637|rcsb pdb:1G5V|rcsb pdb:1MHN|rcsb pdb:2LEH|rcsb pdb:4A4E|rcsb pdb:4A4G|rcsb pdb:4GLI|rcsb pdb:4QQ6|rcsb pdb:5XJL|go:"GO:0034719"(SMN-Sm protein complex)|rcsb pdb:5XJQ|rcsb pdb:5XJR|rcsb pdb:5XJS|rcsb pdb:5XJT|rcsb pdb:5XJU|reactome:R-HSA-191859|go:"GO:0032797"(SMN complex)|refseq:NP_001284644.1|ensembl:ENSP00000305857|ensembl:ENSP00000370083|ensembl:ENSP00000370117|ensembl:ENST00000380742|ensembl:ENSP00000370118|ensembl:ENSP00000370119|ensembl:ENST00000503079|ensembl:ENSP00000428128|ensembl:ENST00000506163|ensembl:ENSP00000424926|ensembl:ENST00000611442|ensembl:ENSP00000483768|ensembl:ENST00000614240|ensembl:ENSP00000479279|ensembl:ENSP00000479920|ensembl:ENST00000614773|ensembl:ENSP00000481427|ensembl:ENSP00000483515|ensembl:ENSP00000483819|ensembl:ENST00000622158|ensembl:ENSP00000480906|ensembl:ENSP00000482966|ensembl:ENST00000624634|ensembl:ENSP00000485595|ensembl:ENST00000626847|ensembl:ENSP00000486152|ensembl:ENSP00000487421|ensembl:ENST00000628353|ensembl:ENSP00000487029|ensembl:ENST00000628642|ensembl:ENSP00000487015|ensembl:ENSP00000487206|refseq:XP_016865275.1|dip:DIP-31309N|entrezgene/locuslink:6607(identity)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	-	-	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:QGivm7E8suciCWXO4l0zCUzCl2g9606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:202E082F8B13E2CB|rigid:Kq/4LIJwTNVmItvsCg9v0/vIhBM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q15427	uniprotkb:P38340	intact:EBI-348469|ensembl:ENSP00000271628|intact:EBI-1047735|uniprotkb:Q5SZ63	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:sf3b4_human(display_long)|uniprotkb:SF3B4(gene name)|psi-mi:SF3B4(display_short)|uniprotkb:SAP49(gene name synonym)|uniprotkb:Spliceosome-associated protein 49(gene name synonym)|uniprotkb:Pre-mRNA-splicing factor SF3b 49 kDa subunit(gene name synonym)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11557905|imex:IM-24995-4672	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005841.1|ensembl:ENSG00000143368(gene)|ensembl:ENST00000271628(transcript)|rcsb pdb:6QX9|rcsb pdb:6Y53|rcsb pdb:6Y5Q|rcsb pdb:7ABG|rcsb pdb:7ABH|rcsb pdb:7ABI|rcsb pdb:7DVQ|reactome:R-HSA-72163|reactome:R-HSA-72165|rcsb pdb:6AHD|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:1990935"(splicing factor binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034158|go:"GO:0000375"(RNA splicing, via transesterification reactions)|interpro:IPR034159|interpro:IPR035979|mint:Q15427|rcsb pdb:1X5T|rcsb pdb:5GVQ|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|entrezgene/locuslink:10262(identity)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	-	-	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Jgy6WmBFKkphpZLLte2GgsagUVI9606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:8E934AD975A28E73|rigid:3VKOeIx9t1GaLwUpa67IqPqIbOA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q15415	uniprotkb:P38340	intact:EBI-8642021|uniprotkb:B2R916|intact:MINT-8163253|ensembl:ENSP00000250831|ensembl:ENSP00000307155	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:rby1f_human(display_long)|uniprotkb:RBMY1F(gene name)|psi-mi:RBMY1F(display_short)|uniprotkb:RBMY1J(gene name)|psi-mi:RBMY1J(display_short)|uniprotkb:Y chromosome RNA recognition motif 2(gene name synonym)|uniprotkb:YRRM2(gene name synonym)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11557896|imex:IM-24995-4671	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001290339.1|refseq:NP_001006117.2|refseq:NP_689798.1|ensembl:ENSG00000169800(gene)|ensembl:ENSG00000226941(gene)|ensembl:ENST00000250831(transcript)|ensembl:ENST00000303766(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016607"(nuclear speck)|go:"GO:0042802"(identical protein binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012604(RBM1CTR)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|entrezgene/locuslink:159163(identity)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	-	comment:mint	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:lEyv+LmtOFRifaC5g6jDlh5WCnM9606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:F1F7468E78FC1582|rigid:wQHrJT0tIFinJYuQMAAo3VWix+M	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38340	uniprotkb:Q16637-3	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-395447|ensembl:ENSP00000424926|ensembl:ENSP00000486152|ensembl:ENSP00000487015|ensembl:ENSP00000487029|intact:EBI-8628183|intact:MINT-95595	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:q16637-3(display_long)|uniprotkb:Iso7-SMN(isoform synonym)|uniprotkb:SMN1(gene name)|psi-mi:SMN1(display_short)|uniprotkb:SMN2(gene name)|psi-mi:SMN2(display_short)|uniprotkb:SMN(gene name synonym)|uniprotkb:SMNT(gene name synonym)|uniprotkb:SMNC(gene name synonym)|uniprotkb:Component of gems 1(gene name synonym)|uniprotkb:Gemin-1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11557923|imex:IM-24995-4674	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	intact:EBI-395421(smn_human)|ensembl:ENSG00000275349(gene)|ensembl:ENST00000506163(transcript)|ensembl:ENST00000626847(transcript)|ensembl:ENST00000628353(transcript)|ensembl:ENST00000628642(transcript)|ensembl:ENSG00000172062(gene)|ensembl:ENSG00000205571(gene)|ensembl:ENSG00000273772(gene)|uniprotkb:Q16637-3(isoform-parent)|entrezgene/locuslink:6607(identity)	-	crc64:66699F37B0013088	isoform-comment:Thought to be a non-functional protein that lacks the capacity to oligomerize and thus cannot interact with Sm proteins. Primarily derived from SMN2 gene.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:ICA63eidVxJ219M+YZJ20zNh+xU9606	intact-crc:64E026FF8CBBA02D|rigid:wu48ZQpwfDqQm7Y7vGLoNyQek4Q	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38340	uniprotkb:Q53EZ4	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-747776|uniprotkb:Q32WF5|uniprotkb:Q3MV20|uniprotkb:Q5VY28|uniprotkb:Q6N034|ensembl:ENSP00000360540|uniprotkb:Q96H32|uniprotkb:Q9NVS7|uniprotkb:B2RDG8|intact:EBI-10173536|uniprotkb:D3DR37|intact:EBI-28973801	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:cep55_human(display_long)|uniprotkb:Up-regulated in colon cancer 6(gene name synonym)|uniprotkb:CEP55(gene name)|psi-mi:CEP55(display_short)|uniprotkb:URCC6(gene name synonym)|uniprotkb:C10orf3(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11557932|imex:IM-24995-4675	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	refseq:NP_001120654.1|refseq:NP_060601.3|ensembl:ENSG00000138180(gene)|ensembl:ENST00000371485(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0014066"(regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0030496"(midbody)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042802"(identical protein binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0061952"(midbody abscission)|go:"GO:0090543"(Flemming body)|go:"GO:1904888"(cranial skeletal system development)|interpro:IPR022008|interpro:IPR038926|mint:Q53EZ4|rcsb pdb:3E1R|rcsb pdb:3WUT|rcsb pdb:3WUU|rcsb pdb:3WUV|go:"GO:0005814"(centriole)|ensembl:ENSP00000360540|dip:DIP-44581N|entrezgene/locuslink:55165(identity)	-	crc64:66699F37B0013088	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:tuo36vVb8ZgPDR81YjZFNEg559w9606	intact-crc:E454792F27CDD8A3|rigid:dnMfuhgSQScUNIvPg2emyYRhpSc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38340	uniprotkb:Q6RW13-2	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-11522760|ensembl:ENSP00000365816	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:q6rw13-2(display_long)|uniprotkb:AGTRAP(gene name)|psi-mi:AGTRAP(display_short)|uniprotkb:AT1 receptor-associated protein(gene name synonym)|uniprotkb:ATRAP(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11557968|imex:IM-24995-4679	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	ensembl:ENSG00000177674(gene)|ensembl:ENST00000376629(transcript)|intact:EBI-741181(isoform-parent)|uniprotkb:Q6RW13-2(isoform-parent)|entrezgene/locuslink:57085(identity)	-	crc64:66699F37B0013088	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:PNzVis/8puQZBJ562gCqZKc078s9606	intact-crc:2B6C4680098DE581|rigid:A+Xt1mCM+n7/uS0ETA2CRRNAvNY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q86UW9	uniprotkb:P38340	intact:EBI-740376|uniprotkb:Q96H69|uniprotkb:Q9H890|uniprotkb:Q9P200|uniprotkb:Q6XM88|ensembl:ENSP00000322885|ensembl:ENSP00000390218|ensembl:ENSP00000411986|uniprotkb:Q6XM87|intact:EBI-10192429|uniprotkb:Q4ZH49	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:dtx2_human(display_long)|uniprotkb:RING finger protein 58(gene name synonym)|uniprotkb:DTX2(gene name)|psi-mi:DTX2(display_short)|uniprotkb:KIAA1528(gene name synonym)|uniprotkb:RNF58(gene name synonym)|uniprotkb:Protein deltex-2(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase DTX2(gene name synonym)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11557977|imex:IM-24995-4680	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001096064.1|refseq:NP_001096065.1|refseq:NP_001096066.1|refseq:NP_065943.2|ensembl:ENSP00000322885|ensembl:ENSP00000390218|ensembl:ENSP00000411986|ensembl:ENST00000446820|ensembl:ENSP00000392545|ensembl:ENSG00000091073(gene)|ensembl:ENST00000324432(transcript)|ensembl:ENST00000413936(transcript)|ensembl:ENST00000430490(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031965"(nuclear membrane)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR004170(WWE)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR018123|interpro:IPR018957|interpro:IPR037197|interpro:IPR039396|interpro:IPR039398|interpro:IPR039399|mint:Q86UW9|rcsb pdb:6IR0|rcsb pdb:6Y22|rcsb pdb:6Y2X|rcsb pdb:6Y3J|reactome:R-HSA-2122948|refseq:XP_011514074.1|refseq:XP_011514075.1|refseq:XP_011514076.1|refseq:XP_011514077.1|refseq:XP_005250188.1|refseq:XP_005250189.1|refseq:XP_016867212.1|refseq:XP_016867213.1|refseq:XP_016867214.1|refseq:XP_016867215.1|refseq:XP_016867216.1|entrezgene/locuslink:113878(identity)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	-	-	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:ugnjqAbG6Ekyc8MGugCnjc9zVaI9606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:00ACEACAD4141546|rigid:1Ha/wQdxNX3u33uinTzJuwTQHR4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38340	uniprotkb:Q5T124-6	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-11524408	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:q5t124-6(display_long)|uniprotkb:UBXN11(gene name)|psi-mi:UBXN11(display_short)|uniprotkb:Colorectal tumor-associated antigen COA-1(gene name synonym)|uniprotkb:SOC(gene name synonym)|uniprotkb:Socius(gene name synonym)|uniprotkb:UBX domain-containing protein 5(gene name synonym)|uniprotkb:UBXD5(gene name synonym)|uniprotkb:PP2243(orf name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11557950|imex:IM-24995-4677	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	intact:EBI-746004(isoform-parent)|uniprotkb:Q5T124-6(isoform-parent)|entrezgene/locuslink:91544(identity)	-	crc64:66699F37B0013088	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:1YSjG/p2ihcjl4P8KdPCaX2HxiY9606	intact-crc:8E36450514CB349C|rigid:mJIZimAvyqKNqPRmPVlcNf+vq5E	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q5JST6	uniprotkb:P38340	intact:EBI-2349927|uniprotkb:Q9H653|uniprotkb:Q5JST8|uniprotkb:Q68DK4|uniprotkb:Q8NEI0|intact:EBI-28971886|ensembl:ENSP00000404232	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:efhc2_human(display_long)|uniprotkb:EFHC2(gene name)|psi-mi:EFHC2(display_short)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11557941|imex:IM-24995-4676	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000404232|refseq:NP_079460.2|ensembl:ENSG00000183690(gene)|ensembl:ENST00000420999(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005930"(axoneme)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0060285"(cilium-dependent cell motility)|go:"GO:0072686"(mitotic spindle)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR006602(Region of unknown function DM10)|interpro:IPR011992(EF-Hand type)|interpro:IPR040193|rcsb pdb:2Z13|rcsb pdb:2Z14|entrezgene/locuslink:80258(identity)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	-	-	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:O1XriQSkLcYkk7H7AlanQ1FKIBY9606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:6458E16F64E8A04D|rigid:sbi4qDEg3OEUgfzrgQnqO7aHA24	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q5VWX1	uniprotkb:P38340	intact:EBI-742808|uniprotkb:Q8TCZ4|uniprotkb:Q8N4I4|uniprotkb:A8K7M8|ensembl:ENSP00000281156	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:khdr2_human(display_long)|uniprotkb:SLM1(gene name synonym)|uniprotkb:Sam68-like mammalian protein 1(gene name synonym)|uniprotkb:KHDRBS2(gene name)|psi-mi:KHDRBS2(display_short)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11557959|imex:IM-24995-4678	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_689901.2|ensembl:ENSG00000112232(gene)|ensembl:ENST00000281156(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008143"("poly(A) binding")|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0017124"(SH3 domain binding)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR032335|interpro:IPR032571|interpro:IPR036612|reactome:R-HSA-8849468|entrezgene/locuslink:202559(identity)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	-	-	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:IfFvZO2dIAo0Sdx+BUb5c8F7aQY9606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:E31B52B7104A64B6|rigid:0T4js7J5FoPVuVYAEbM1jIc36Ic	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q86WT6-2	uniprotkb:P38340	intact:EBI-11525489|ensembl:ENSP00000342922|ensembl:ENSP00000479720	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:q86wt6-2(display_long)|uniprotkb:RING-type E3 ubiquitin transferase TRIM69(gene name synonym)|uniprotkb:TRIM69(gene name)|psi-mi:TRIM69(display_short)|uniprotkb:RFP-like domain-containing protein trimless(gene name synonym)|uniprotkb:RING finger protein 36(gene name synonym)|uniprotkb:RNF36(gene name synonym)|uniprotkb:Tripartite motif-containing protein 69(gene name synonym)|uniprotkb:HSD-34(orf name)|uniprotkb:HSD34(orf name)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11557987|imex:IM-24995-4681	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-749955(isoform-parent)|uniprotkb:Q86WT6-2(isoform-parent)|ensembl:ENSG00000185880(gene)|ensembl:ENSG00000278211(gene)|ensembl:ENST00000338264(transcript)|ensembl:ENST00000618398(transcript)|entrezgene/locuslink:140691(identity)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	-	-	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:J0mzn4PSX5vWZqt4X3Ee1Wxx5hw9606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:8E10D5EFA1319F09|rigid:rYUx2nVbzRHViiZnnNUPEFxMCpA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38340	uniprotkb:Q8IUQ4-2	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-11522811|ensembl:ENSP00000349156	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:q8iuq4-2(display_long)|uniprotkb:SIAH1(gene name)|psi-mi:SIAH1(display_short)|uniprotkb:HUMSIAH(gene name synonym)|uniprotkb:Seven in absentia homolog 1(gene name synonym)|uniprotkb:Siah-1a(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase SIAH1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11557996|imex:IM-24995-4682	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	intact:EBI-747107(isoform-parent)|ensembl:ENSG00000196470(gene)|ensembl:ENST00000356721(transcript)|uniprotkb:Q8IUQ4-2(isoform-parent)|entrezgene/locuslink:6477(identity)	-	crc64:66699F37B0013088	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:M4q06jVbWuq1mGMXvtuFBaMEgZM9606	intact-crc:6FDE4BDBF9923BA6|rigid:0el1JYLTyDSSh/VBenuQxdsjgiE	false	-	sufficient binding region:32-313	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38340	uniprotkb:Q8IXK0-5	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-11527347|ensembl:ENSP00000507877	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:q8ixk0-5(display_long)|uniprotkb:EDR2(gene name synonym)|uniprotkb:Early development regulatory protein 2(gene name synonym)|uniprotkb:PH2(gene name synonym)|uniprotkb:PHC2(gene name)|psi-mi:PHC2(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11558007|imex:IM-24995-4683	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	ensembl:ENSG00000134686(gene)|ensembl:ENST00000683057(transcript)|intact:EBI-713786(isoform-parent)|uniprotkb:Q8IXK0-5(isoform-parent)|entrezgene/locuslink:1912(identity)	-	crc64:66699F37B0013088	isoform-comment:No experimental confirmation available.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:bkZ10pedX8mCMrcppjyd4tl7hm09606	intact-crc:E5DDA0BF6E31644E|rigid:UK282+UTG2MbTh7PNk4WAupJt0w	false	-	sufficient binding region:537-859	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8N6K7-2	uniprotkb:P38340	intact:EBI-11528848|ensembl:ENSP00000324874	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:q8n6k7-2(display_long)|uniprotkb:SAMD3(gene name)|psi-mi:SAMD3(display_short)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11558029|imex:IM-24995-4685	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-748741(isoform-parent)|ensembl:ENSG00000164483(gene)|ensembl:ENST00000324172(transcript)|uniprotkb:Q8N6K7-2(isoform-parent)|entrezgene/locuslink:154075(identity)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	-	isoform-comment:No experimental confirmation available.	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:2ZsHFOFMqw/yebw24QlvgpYFVso9606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:B22A399B6FB49797|rigid:bEcj5U8qypoTMCNPiWZwGC6WGYY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38340	uniprotkb:Q8NA61-2	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-11524851|ensembl:ENSP00000368249|ensembl:ENSP00000480148	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:q8na61-2(display_long)|uniprotkb:CBY2(gene name)|psi-mi:CBY2(display_short)|uniprotkb:SPERT(gene name synonym)|uniprotkb:Spermatid-associated protein(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11558038|imex:IM-24995-4686	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	intact:EBI-741724(isoform-parent)|ensembl:ENSG00000174015(gene)|ensembl:ENST00000378966(transcript)|ensembl:ENST00000610924(transcript)|uniprotkb:Q8NA61-2(isoform-parent)|entrezgene/locuslink:220082(identity)	-	crc64:66699F37B0013088	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:SogYcXGGMYRYzB9xKC5o0pEtsDs9606	intact-crc:169FB81A70199E43|rigid:NhAM0HIjA6aSDU1k4mqFLCknSvI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38340	uniprotkb:Q8NDC0	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-741424|uniprotkb:Q96BG5|ensembl:ENSP00000378851|ensembl:ENSP00000481882|uniprotkb:B2RDD8	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:missl_human(display_long)|uniprotkb:C14orf32(gene name synonym)|uniprotkb:Mitogen-activated protein kinase 1-interacting protein 1-like(gene name synonym)|uniprotkb:MAPK1IP1L(gene name)|psi-mi:MAPK1IP1L(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11558047|imex:IM-24995-4687	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	refseq:NP_653179.1|ensembl:ENSG00000168175(gene)|ensembl:ENST00000395468(transcript)|ensembl:ENST00000622254(transcript)|interpro:IPR031653|entrezgene/locuslink:93487(identity)	-	crc64:66699F37B0013088	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:CX220vB2TjggPEso5CHNUVzl79g9606	intact-crc:43573BC23C78BC37|rigid:WWegKoQBJiuvFiywqiCXJStd3AI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38340	uniprotkb:Q8NHQ1	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-739624|ensembl:ENSP00000264982|ensembl:ENSP00000419231|uniprotkb:Q96B31|uniprotkb:Q9H2C3|uniprotkb:Q9H2Z1|uniprotkb:Q9H940|uniprotkb:D3DNE9|uniprotkb:B7Z5I8|uniprotkb:B7Z7E8|uniprotkb:F5GZX8	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:cep70_human(display_long)|uniprotkb:CEP70(gene name)|psi-mi:CEP70(display_short)|uniprotkb:BITE(gene name synonym)|uniprotkb:p10-binding protein(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11558056|imex:IM-24995-4688	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	ensembl:ENSG00000114107(gene)|ensembl:ENST00000264982(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|interpro:IPR019734|interpro:IPR037692|mint:Q8NHQ1|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|ensembl:ENST00000484888(transcript)|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_077817.2|refseq:XP_016862764.1|refseq:NP_001275893.1|refseq:NP_001275894.1|refseq:NP_001275895.1|refseq:NP_001275896.1|refseq:NP_001307527.1|refseq:NP_001307529.1|entrezgene/locuslink:80321(identity)	-	crc64:66699F37B0013088	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:S4yveQWcvdVtAUX65gqrJ5Dv0Mc9606	intact-crc:61F25543B888B40A|rigid:tp1An3X6liuUeZd/ZN9x5Ms1p3M	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8N0S2	uniprotkb:P38340	intact:EBI-6872807|ensembl:ENSP00000341282|uniprotkb:Q9BWU4|uniprotkb:B2RC80|uniprotkb:Q9BWU3	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:syce1_human(display_long)|uniprotkb:C10orf94(gene name synonym)|uniprotkb:Cancer/testis antigen 76(gene name synonym)|uniprotkb:SYCE1(gene name)|psi-mi:SYCE1(display_short)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11558018|imex:IM-24995-4684	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000171772(gene)|ensembl:ENST00000343131(transcript)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0000801"(central element)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051301"(cell division)|interpro:IPR026676|reactome:R-HSA-1221632|refseq:NP_001137235.1|refseq:NP_570140.1|entrezgene/locuslink:93426(identity)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	-	-	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:qLVqIlFiwZJHFfoyYXV3jrqdd609606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:F66FC705D81EC428|rigid:D4In7CizkteBP9/zVwBSbM0sqmA	false	sufficient binding region:37-351	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8WW34-2	uniprotkb:P38340	intact:EBI-11528917|ensembl:ENSP00000369959	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:q8ww34-2(display_long)|uniprotkb:TMEM239(gene name)|psi-mi:TMEM239(display_short)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11558092|imex:IM-24995-4692	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-9675724(isoform-parent)|uniprotkb:Q8WW34-2(isoform-parent)|ensembl:ENSG00000198326(gene)|ensembl:ENST00000380585(transcript)|entrezgene/locuslink:100288797(identity)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	-	isoform-comment:No experimental confirmation available.	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:1VqWIwPpWs6WjW8eDoJUHz2pegw9606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:D52E8651D65C0337|rigid:N6bd/BTl+wSDGwf83LA5bfD+5CM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38340	uniprotkb:Q93062-3	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-740343|ensembl:ENSP00000340176	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:q93062-3(display_long)|uniprotkb:RBPMS(gene name)|psi-mi:RBPMS(display_short)|uniprotkb:HERMES(gene name synonym)|uniprotkb:Heart and RRM expressed sequence(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11558101|imex:IM-24995-4693	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	intact:EBI-740322(rbpms_human)|uniprotkb:Q93062-3(isoform-parent)|ensembl:ENSG00000157110(gene)|ensembl:ENST00000339877(transcript)|entrezgene/locuslink:11030(identity)	-	crc64:66699F37B0013088	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:nlPMQAJoKEbPYBwsL3xodmCKd7c9606	intact-crc:C09EFBEC8C21E047|rigid:jAPBmauEX7JrUhtS3lKietn4MpQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38340	uniprotkb:Q8NHQ1-3	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-11526150|ensembl:ENSP00000419743	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:q8nhq1-3(display_long)|uniprotkb:CEP70(gene name)|psi-mi:CEP70(display_short)|uniprotkb:BITE(gene name synonym)|uniprotkb:p10-binding protein(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11558065|imex:IM-24995-4689	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	ensembl:ENSG00000114107(gene)|ensembl:ENST00000464035(transcript)|intact:EBI-739624(isoform-parent)|uniprotkb:Q8NHQ1-3(isoform-parent)|entrezgene/locuslink:80321(identity)	-	crc64:66699F37B0013088	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:hoF4iYo+GzWQ21hoaWZfTftWKCc9606	intact-crc:C80483A2D9920B09|rigid:VGCTdbYQlaQljsg+888qhNQjDFE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8TAP6	uniprotkb:P38340	intact:EBI-742887|ensembl:ENSP00000262127|uniprotkb:Q658N5|uniprotkb:Q9H9U7|uniprotkb:B0YJB2|uniprotkb:B4DXG5|uniprotkb:B4DZW1	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:cep76_human(display_long)|uniprotkb:CEP76(gene name)|psi-mi:CEP76(display_short)|uniprotkb:C18orf9(gene name synonym)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11558074|imex:IM-24995-4690	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_079175.2|ensembl:ENSG00000101624(gene)|ensembl:ENST00000262127(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0046599"(regulation of centriole replication)|interpro:IPR028926|interpro:IPR038765|mint:Q8TAP6|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_001258918.1|entrezgene/locuslink:79959(identity)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	-	-	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:fWzb8oIU35oVWomyDrf8u5sbxUk9606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:03B8373601519941|rigid:b2+5OSmw5xO3lz9jgC8XS5gTSMk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8WVF5	uniprotkb:P38340	intact:EBI-741463|ensembl:ENSP00000368402|uniprotkb:Q5W0P9	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:kctd4_human(display_long)|uniprotkb:KCTD4(gene name)|psi-mi:KCTD4(display_short)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11558083|imex:IM-24995-4691	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000180332(gene)|ensembl:ENST00000379108(transcript)|go:"GO:0051260"(protein homooligomerization)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR003131(Potassium channel, voltage dependent, Kv,  tetramerisation)|interpro:IPR011333(BTB/POZ fold)|refseq:NP_940686.2|entrezgene/locuslink:386618(identity)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	-	-	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:03cd1lqmT8fReXzYqjrKSWUdqY89606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:EEBC502DA0410544|rigid:VEISpv+OQR1w87VcnwpVTRsUVoQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38340	uniprotkb:Q96CD2	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-724333|uniprotkb:Q96SX0|ensembl:ENSP00000343190|uniprotkb:Q9HC17	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:coac_human(display_long)|uniprotkb:CoaC(gene name synonym)|uniprotkb:PPCDC(gene name)|psi-mi:PPCDC(display_short)|uniprotkb:COAC(gene name synonym)|uniprotkb:MDS018(orf name)|uniprotkb:UNQ9365/PRO34154(orf name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11558137|imex:IM-24995-4697	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	refseq:NP_068595.3|rcsb pdb:1QZU|reactome:R-HSA-196783|mint:Q96CD2|ensembl:ENSG00000138621(gene)|ensembl:ENST00000342932(transcript)|go:"GO:0004633"(phosphopantothenoylcysteine decarboxylase activity)|go:"GO:0005829"(cytosol)|go:"GO:0010181"(FMN binding)|go:"GO:0015937"(coenzyme A biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0071513"(phosphopantothenoylcysteine decarboxylase complex)|interpro:IPR003382(Flavoprotein)|interpro:IPR036551|refseq:NP_001288030.1|refseq:NP_001288031.1|refseq:NP_001288032.1|refseq:NP_001288033.1|refseq:NP_001288034.1|entrezgene/locuslink:60490(identity)	-	crc64:66699F37B0013088	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:2d686R1m4jA5uWpf/8O6rI6/Olo9606	intact-crc:68BBBD01472EDEB8|rigid:Ie5XThJd1VV+gcdIt5EeSfKwT1g	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q969F0	uniprotkb:P38340	intact:EBI-743099|ensembl:ENSP00000359375	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:fate1_human(display_long)|uniprotkb:Tumor antigen BJ-HCC-2(gene name synonym)|uniprotkb:Cancer/testis antigen 43(gene name synonym)|uniprotkb:FATE1(gene name)|psi-mi:FATE1(display_short)|uniprotkb:FATE(gene name synonym)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11558110|imex:IM-24995-4694	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_149076.1|ensembl:ENSG00000147378(gene)|ensembl:ENST00000370350(transcript)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|go:"GO:0051562"(negative regulation of mitochondrial calcium ion concentration)|interpro:IPR039153|interpro:IPR039433|mint:Q969F0|entrezgene/locuslink:89885(identity)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	-	-	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Nm1N6lO92MHr5rIKC007oouF5RE9606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:CF614EFECB217340|rigid:/+zc1OuYwsGDsNuo4mQd/iw7VIE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38340	uniprotkb:Q96DZ9-2	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-11522780|ensembl:ENSP00000352270|ensembl:ENSP00000497215	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:q96dz9-2(display_long)|uniprotkb:CMTM5(gene name)|psi-mi:CMTM5(display_short)|uniprotkb:CKLFSF5(gene name synonym)|uniprotkb:Chemokine-like factor superfamily member 5(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11558146|imex:IM-24995-4698	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	ensembl:ENSG00000166091(gene)|ensembl:ENST00000359320(transcript)|ensembl:ENST00000649278(transcript)|intact:EBI-2548702(isoform-parent)|uniprotkb:Q96DZ9-2(isoform-parent)|entrezgene/locuslink:116173(identity)	-	crc64:66699F37B0013088	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:2TJ7rZKQNb5hH5gz9i+ujOEOIOg9606	intact-crc:36AD5D2461FFE6DA|rigid:7Tza29kWNlcvzcQUi0MEeZ+mf3s	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96BR9	uniprotkb:P38340	intact:EBI-742740|uniprotkb:Q8IUL5|uniprotkb:Q8IWR9|uniprotkb:Q8N2Y5|uniprotkb:Q96BX0|ensembl:ENSP00000362609	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:zbt8a_human(display_long)|uniprotkb:ZBTB8A(gene name)|psi-mi:ZBTB8A(display_short)|uniprotkb:BOZF1(gene name synonym)|uniprotkb:BTB/POZ and zinc-finger domain-containing factor(gene name synonym)|uniprotkb:BTB/POZ and zinc-finger domains factor on chromosome 1(gene name synonym)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11558128|imex:IM-24995-4696	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000160062(gene)|ensembl:ENST00000373510(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|refseq:NP_001035531.2|refseq:NP_001278425.1|entrezgene/locuslink:653121(identity)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	-	-	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:tsrPT2tHvuBryODKgRXnceXz9s09606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:F373DFD779BF132D|rigid:DuH/mBVmT+SjtiDNS+xDBvkP3c0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96AA8	uniprotkb:P38340	intact:EBI-752007|uniprotkb:O60302|uniprotkb:B4DSG0|uniprotkb:A4ZZA7|uniprotkb:Q548S1|uniprotkb:A8K5G5|uniprotkb:G5E9Y0|ensembl:ENSP00000265272	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:jkip2_human(display_long)|uniprotkb:JAMIP2(gene name synonym)|uniprotkb:NECC1(gene name synonym)|uniprotkb:Neuroendocrine long coiled-coil protein 1(gene name synonym)|uniprotkb:CTCL tumor antigen HD-CL-04(gene name synonym)|uniprotkb:JAKMIP2(gene name)|psi-mi:JAKMIP2(display_short)|uniprotkb:KIAA0555(gene name synonym)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11558119|imex:IM-24995-4695	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055605.2|refseq:NP_001257870.1|refseq:NP_001257863.1|refseq:NP_001269211.1|refseq:XP_016865586.1|ensembl:ENSG00000176049(gene)|ensembl:ENST00000265272(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0008017"(microtubule binding)|go:"GO:0019900"(kinase binding)|interpro:IPR024836|interpro:IPR031994|entrezgene/locuslink:9832(identity)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	-	-	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:WnaHkeDBQXut9F9AzzaCrDYpmAE9606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:B6FF3644B8ED3972|rigid:npYgIZdHQ/NERxzGsNzFH1B4wyU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96MF2	uniprotkb:P38340	intact:EBI-745680|uniprotkb:B4DUK9|uniprotkb:Q96HU5|ensembl:ENSP00000329200	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:stac3_human(display_long)|uniprotkb:STAC3(gene name)|psi-mi:STAC3(display_short)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11558186|imex:IM-24995-4702	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001273185.1|refseq:NP_001273186.1|refseq:NP_659501.1|refseq:XP_011536428.1|ensembl:ENSG00000185482(gene)|ensembl:ENST00000332782(transcript)|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0030315"(T-tubule)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:1901387"(positive regulation of voltage-gated calcium channel activity)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|interpro:IPR001452(Src homology-3)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR035736|interpro:IPR036028|interpro:IPR039688|mint:Q96MF2|rcsb pdb:2DB6|rcsb pdb:6B29|rcsb pdb:6UY7|rcsb pdb:6UY8|rcsb pdb:6UY9|entrezgene/locuslink:246329(identity)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	-	-	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:PzyVrp74OzLhtbODzinH5fHSGRc9606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:93296919AE08FE4D|rigid:7E6s5XTKhed7xn4oHkLVynXBEvY	false	sufficient binding region:40-364	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38340	uniprotkb:Q96MA1	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-954466|uniprotkb:Q96SD2|ensembl:ENSP00000360500	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:dmrtb_human(display_long)|uniprotkb:DMRTB1(gene name)|psi-mi:DMRTB1(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11558175|imex:IM-24995-4701	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|ensembl:ENSG00000143006(gene)|ensembl:ENST00000371445(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007281"(germ cell development)|go:"GO:0007548"(sex differentiation)|go:"GO:0046872"(metal ion binding)|interpro:IPR001275(DM DNA-binding)|interpro:IPR026607|interpro:IPR036407|mint:Q96MA1|refseq:NP_149056.1|ensembl:ENSP00000360500|entrezgene/locuslink:63948(identity)	-	crc64:66699F37B0013088	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:GU1xgsv/Oyy91PEorOlxBqAvIzc9606	intact-crc:B2D6D46CC14E4490|rigid:XEOf/4DkhSl+14Sc5v3TJ+135Jo	false	-	sufficient binding region:154-342	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38340	uniprotkb:Q96HR9	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-750345|uniprotkb:Q96LM0|uniprotkb:B2RE01|uniprotkb:A0A1L5BXV3|uniprotkb:D6W5Z0|ensembl:ENSP00000378861	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:reep6_human(display_long)|uniprotkb:Polyposis locus protein 1-like 1(gene name synonym)|uniprotkb:REEP6(gene name)|psi-mi:REEP6(display_short)|uniprotkb:C19orf32(gene name synonym)|uniprotkb:DP1L1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11558166|imex:IM-24995-4700	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	refseq:NP_612402.1|refseq:NP_001316485.1|ensembl:ENSG00000115255(gene)|ensembl:ENST00000395479(transcript)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030665"(clathrin-coated vesicle membrane)|go:"GO:0032386"(regulation of intracellular transport)|go:"GO:0050908"(detection of light stimulus involved in visual perception)|interpro:IPR004345(TB2/DP1 and HVA22 related protein)|mint:Q96HR9|reactome:R-HSA-381753|go:"GO:0005634"(nucleus)|entrezgene/locuslink:92840(identity)	-	crc64:66699F37B0013088	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2017/05/05	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:pB8AjjNTpmaaLJ8j7MCBM45UAHE9606	intact-crc:5F5370CEBC018F93|rigid:L17CSpZs0kLHM9zevg3Ez0Ws3s4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96EY1-3	uniprotkb:P38340	intact:EBI-11526226|ensembl:ENSP00000393970	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:q96ey1-3(display_long)|uniprotkb:DnaJ protein Tid-1(gene name synonym)|uniprotkb:HCA57(gene name synonym)|uniprotkb:Hepatocellular carcinoma-associated antigen 57(gene name synonym)|uniprotkb:TID1(gene name synonym)|uniprotkb:Tumorous imaginal discs protein Tid56 homolog(gene name synonym)|uniprotkb:DNAJA3(gene name)|psi-mi:DNAJA3(display_short)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11558155|imex:IM-24995-4699	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-356767(isoform-parent)|ensembl:ENSG00000103423(gene)|ensembl:ENST00000431375(transcript)|uniprotkb:Q96EY1-3(isoform-parent)|entrezgene/locuslink:9093(identity)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	-	isoform-comment:"Ref.3 (BAG58345) sequence is in conflict in position: 33:Y->H."	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:nMH4IaOZYO5w5bh+cdX4LoPSisc9606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:9EF1ED79CC7BE3AA|rigid:k6U6xtX0na4XLi0xPmqP91pJVWY	false	sufficient binding region:60-300	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38340	uniprotkb:Q96PU8	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-945792|uniprotkb:Q2I375|uniprotkb:Q5MJQ1|uniprotkb:Q969L9|uniprotkb:Q96EJ3|uniprotkb:Q96KA3|uniprotkb:Q96PU6|uniprotkb:Q96PU7|uniprotkb:Q9P0X6|uniprotkb:Q9P0X7|uniprotkb:Q9P0X8|uniprotkb:Q9P0X9|uniprotkb:Q9P0Y0|uniprotkb:Q9P0Y1|ensembl:ENSP00000355094	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:qki_human(display_long)|uniprotkb:QKI(gene name)|psi-mi:QKI(display_short)|uniprotkb:HKQ(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11558197|imex:IM-24995-4703	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	refseq:NP_006766.1|refseq:NP_996735.1|refseq:NP_996736.1|refseq:NP_996737.1|refseq:NP_001288014.1|refseq:XP_011534561.1|ensembl:ENSG00000112531(gene)|ensembl:ENST00000361752(transcript)|go:"GO:0001570"(vasculogenesis)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0006417"(regulation of translation)|go:"GO:0007286"(spermatid development)|go:"GO:0008380"(RNA splicing)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0042552"(myelination)|go:"GO:0042692"(muscle cell differentiation)|go:"GO:0042759"(long-chain fatty acid biosynthetic process)|go:"GO:0045202"(synapse)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0051028"(mRNA transport)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR032367|interpro:IPR032377|interpro:IPR036612|mint:Q96PU8|rcsb pdb:4JVH|reactome:R-HSA-6802952|entrezgene/locuslink:9444(identity)	-	crc64:66699F37B0013088	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:7dcw5OyNAhQTE+yTch3qbSlZJdE9606	intact-crc:FC4BD39AF7E9DC50|rigid:gys1RPpQVAeyV88aDboHQby7lpw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38340	uniprotkb:Q9BV19	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-2874661|ensembl:ENSP00000361603	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:ca050_human(display_long)|uniprotkb:C1orf50(gene name)|psi-mi:C1orf50(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11558242|imex:IM-24995-4708	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	ensembl:ENSG00000164008(gene)|ensembl:ENST00000372525(transcript)|go:"GO:0042802"(identical protein binding)|interpro:IPR019534|refseq:NP_077002.2|entrezgene/locuslink:79078(identity)	-	crc64:66699F37B0013088	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:TZfvza3lr44CQW5Piu+83qv5Igo9606	intact-crc:10B146DBB1B6C31B|rigid:apcvklzGvvboxdB4d6bfWHA+zIQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9BUZ4	uniprotkb:P38340	intact:EBI-3650647|uniprotkb:O75615|uniprotkb:Q14848|uniprotkb:Q2KJU4|uniprotkb:Q2PJN8|ensembl:ENSP00000262395	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:traf4_human(display_long)|uniprotkb:TRAF4(gene name)|psi-mi:TRAF4(display_short)|uniprotkb:CART1(gene name synonym)|uniprotkb:MLN62(gene name synonym)|uniprotkb:RNF83(gene name synonym)|uniprotkb:Cysteine-rich domain associated with RING and Traf domains protein 1(gene name synonym)|uniprotkb:Metastatic lymph node gene 62 protein(gene name synonym)|uniprotkb:RING finger protein 83(gene name synonym)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11558233|imex:IM-24995-4707	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004286.2|dip:DIP-40910N|ensembl:ENSG00000076604(gene)|ensembl:ENST00000262395(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006915"(apoptotic process)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030323"(respiratory tube development)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031996"(thioesterase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050699"(WW domain binding)|interpro:IPR001293(Zinc finger, TRAF-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|interpro:IPR012227(TNF receptor-associated factor TRAF)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018957|interpro:IPR027138|interpro:IPR037307|interpro:IPR043211|mint:Q9BUZ4|rcsb pdb:2EOD|rcsb pdb:2YUC|rcsb pdb:3ZJB|rcsb pdb:4K8U|rcsb pdb:4M4E|rcsb pdb:5YC1|entrezgene/locuslink:9618(identity)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	-	-	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:9Bjl/NCcleyKgZb7suHw3AVWpG09606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:CE5C55815704EFD8|rigid:IG24QeboR2KuQKIq2Km2w4i+Gto	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38340	uniprotkb:Q9BPX1	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-742664|uniprotkb:Q9UKU3|ensembl:ENSP00000263278	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:dhb14_human(display_long)|uniprotkb:DHRS10(gene name synonym)|uniprotkb:Dehydrogenase/reductase SDR family member 10(gene name synonym)|uniprotkb:17-beta-hydroxysteroid dehydrogenase DHRS10(gene name synonym)|uniprotkb:Retinal short-chain dehydrogenase/reductase retSDR3(gene name synonym)|uniprotkb:HSD17B14(gene name)|psi-mi:HSD17B14(display_short)|uniprotkb:SDR3(gene name synonym)|uniprotkb:SDR47C1(gene name synonym)|uniprotkb:Short chain dehydrogenase/reductase family 47C member 1(gene name synonym)|uniprotkb:UNQ502/PRO474(orf name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11558224|imex:IM-24995-4706	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	refseq:NP_057330.2|ensembl:ENSG00000087076(gene)|ensembl:ENST00000263278(transcript)|go:"GO:0004303"(estradiol 17-beta-dehydrogenase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006706"(steroid catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0044594"("17-beta-hydroxysteroid dehydrogenase (NAD+) activity")|go:"GO:0047045"("testosterone 17-beta-dehydrogenase (NADP+) activity")|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR020904|interpro:IPR036291|rcsb pdb:1YDE|rcsb pdb:5EN4|rcsb pdb:5HS6|rcsb pdb:5ICM|rcsb pdb:5ICS|rcsb pdb:5JS6|rcsb pdb:5JSF|rcsb pdb:5L7T|rcsb pdb:5L7W|rcsb pdb:5L7Y|rcsb pdb:5O42|rcsb pdb:5O43|rcsb pdb:5O6O|rcsb pdb:5O6X|rcsb pdb:5O6Z|rcsb pdb:5O72|rcsb pdb:5O7C|rcsb pdb:6EMM|rcsb pdb:6FFB|rcsb pdb:6G4L|rcsb pdb:6GBT|rcsb pdb:6GTB|rcsb pdb:6GTU|rcsb pdb:6H0M|rcsb pdb:6HNO|rcsb pdb:6QCK|rcsb pdb:6ZDE|rcsb pdb:6ZDI|reactome:R-HSA-193144|entrezgene/locuslink:51171(identity)	-	crc64:66699F37B0013088	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:/t03kHO/EWlqKNv7+TkWbTV9jpM9606	intact-crc:5383AE7AA7A6CC73|rigid:YpBKWwGDzxQyIyVR8BXnGsfOtRo	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38340	uniprotkb:Q99942	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-348482|ensembl:ENSP00000364235|ensembl:ENSP00000387879|ensembl:ENSP00000388795|ensembl:ENSP00000401172|ensembl:ENSP00000413131|ensembl:ENSP00000415127|ensembl:ENSP00000415784|uniprotkb:A2BFI6|uniprotkb:Q0VDB7|uniprotkb:Q9UMQ2|uniprotkb:B2R4K3	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:rnf5_human(display_long)|uniprotkb:RNF5(gene name)|psi-mi:RNF5(display_short)|uniprotkb:G16(gene name synonym)|uniprotkb:RING finger protein 5(gene name synonym)|uniprotkb:Protein G16(gene name synonym)|uniprotkb:NG2(gene name synonym)|uniprotkb:RMA1(gene name synonym)|uniprotkb:Ram1 homolog(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF5(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11558215|imex:IM-24995-4705	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	refseq:NP_008844.1|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009617"(response to bacterium)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031648"(protein destabilization)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0036503"(ERAD pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0044257"(cellular protein catabolic process)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0044390"(ubiquitin-like protein conjugating enzyme binding)|ensembl:ENST00000456167(transcript)|ensembl:ENSG00000183574(gene)|ensembl:ENSG00000204308(gene)|ensembl:ENSG00000223767(gene)|ensembl:ENSG00000225452(gene)|ensembl:ENSG00000227277(gene)|ensembl:ENSG00000228405(gene)|ensembl:ENSG00000228907(gene)|ensembl:ENST00000375094(transcript)|ensembl:ENST00000413786(transcript)|ensembl:ENST00000432616(transcript)|ensembl:ENST00000445885(transcript)|ensembl:ENST00000449794(transcript)|ensembl:ENST00000453473(transcript)|go:"GO:0055085"(transmembrane transport)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|go:"GO:2000785"(regulation of autophagosome assembly)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|reactome:R-HSA-382556|reactome:R-HSA-5678895|reactome:R-HSA-901032|go:"GO:0044877"(protein-containing complex binding)|dip:DIP-29268N|entrezgene/locuslink:6048(identity)	-	crc64:66699F37B0013088	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:eHlCD+xbWmpzFdhVn6OC5MPqeNE9606	intact-crc:6726D127EDA8F5F1|rigid:wnWWHJark3LiQ8F96socQHho5FA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38340	uniprotkb:Q99836	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-447677|uniprotkb:P78397|uniprotkb:Q53XS7|uniprotkb:B4DKH8|uniprotkb:B4DKU4|uniprotkb:J3KPU4|uniprotkb:J3KQ87|uniprotkb:J3KQJ6|uniprotkb:B4DQ60|uniprotkb:B4DQ72|ensembl:ENSP00000379625|ensembl:ENSP00000498360	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:myd88_human(display_long)|uniprotkb:MYD88(gene name)|psi-mi:MYD88(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11558206|imex:IM-24995-4704	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	refseq:NP_001166037.1|refseq:NP_001166039.1|refseq:NP_001166040.1|refseq:NP_002459.2|dip:DIP-31349N|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032740"(positive regulation of interleukin-17 production)|go:"GO:0032747"(positive regulation of interleukin-23 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034158"(toll-like receptor 8 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042802"(identical protein binding)|go:"GO:0042832"(defense response to protozoan)|go:"GO:0050671"(positive regulation of lymphocyte proliferation)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043621"(protein self-association)|go:"GO:0045087"(innate immune response)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:1902622"(regulation of neutrophil migration)|go:"GO:2000338"("regulation of chemokine (C-X-C motif) ligand 1 production")|go:"GO:2000341"("regulation of chemokine (C-X-C motif) ligand 2 production")|interpro:IPR000157(Toll-Interleukin receptor)|interpro:IPR000488(Death)|interpro:IPR011029(DEATH-like)|interpro:IPR017281(Myeloid differentiation primary response protein MyD88)|interpro:IPR034249|interpro:IPR035897|mint:Q99836|rcsb pdb:2JS7|rcsb pdb:2Z5V|rcsb pdb:3MOP|rcsb pdb:4DOM|rcsb pdb:4EO7|rcsb pdb:6I3N|rcsb pdb:7BEQ|rcsb pdb:7BER|rcsb pdb:7L6W|reactome:R-HSA-1236974|reactome:R-HSA-1257604|reactome:R-HSA-166058|reactome:R-HSA-1810476|reactome:R-HSA-209543|reactome:R-HSA-3134963|reactome:R-HSA-5602498|reactome:R-HSA-5602680|reactome:R-HSA-5603037|reactome:R-HSA-5603041|reactome:R-HSA-6811558|reactome:R-HSA-9020702|reactome:R-HSA-975110|reactome:R-HSA-975155|reactome:R-HSA-975871|reactome:R-HSA-975138|ensembl:ENSG00000172936(gene)|ensembl:ENST00000396334(transcript)|ensembl:ENST00000650905(transcript)|go:"GO:0002238"(response to molecule of fungal origin)|go:"GO:0002269"(leukocyte activation involved in inflammatory response)|go:"GO:0002283"(neutrophil activation involved in immune response)|go:"GO:0002755"(MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0005121"(Toll binding)|go:"GO:0005123"(death receptor binding)|go:"GO:0005149"(interleukin-1 receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007254"(JNK cascade)|go:"GO:0008063"(Toll signaling pathway)|go:"GO:0009682"(induced systemic resistance)|go:"GO:0010008"(endosome membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032494"(response to peptidoglycan)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051607"(defense response to virus)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0070498"(interleukin-1-mediated signaling pathway)|go:"GO:0070555"(response to interleukin-1)|go:"GO:0070935"(3'-UTR-mediated mRNA stabilization)|go:"GO:0070944"(neutrophil-mediated killing of bacterium)|go:"GO:0070976"(TIR domain binding)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0090557"(establishment of endothelial intestinal barrier)|go:"GO:0140052"(cellular response to oxidised low-density lipoprotein particle stimulus)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:1900227"(positive regulation of NLRP3 inflammasome complex assembly)|go:"GO:0050830"(defense response to Gram-positive bacterium)|entrezgene/locuslink:4615(identity)	-	crc64:66699F37B0013088	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:B920s5F0eUql/jtwlByyhI7ojGI9606	intact-crc:7D5AC5F0E55D5FE6|rigid:9WjnDYl3V5Wej9V4AXAdqGwm5XY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38340	uniprotkb:Q9NQC3-3	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-11526335|ensembl:ENSP00000378107	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:q9nqc3-3(display_long)|uniprotkb:Foocen(gene name synonym)|uniprotkb:KIAA0886(gene name synonym)|uniprotkb:NOGO(gene name synonym)|uniprotkb:Neurite outgrowth inhibitor(gene name synonym)|uniprotkb:Neuroendocrine-specific protein(gene name synonym)|uniprotkb:Neuroendocrine-specific protein C homolog(gene name synonym)|uniprotkb:RTN-x(gene name synonym)|uniprotkb:Reticulon-5(gene name synonym)|uniprotkb:My043(orf name)|uniprotkb:SP1507(orf name)|uniprotkb:Foocen-S(isoform synonym)|uniprotkb:Nogo-C(isoform synonym)|uniprotkb:RTN4(gene name)|psi-mi:RTN4(display_short)|uniprotkb:RTN4C(isoform synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11558287|imex:IM-24995-4713	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	intact:EBI-715945(isoform-parent)|ensembl:ENSG00000115310(gene)|ensembl:ENST00000394609(transcript)|entrezgene/locuslink:57142(identity)	-	crc64:66699F37B0013088	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:Iq/LlFtXjFyIIfxZ1l3NTKURpyA9606	intact-crc:0932E74B74C4983E|rigid:RPbYVC0UaomGCxRAx3vYWwqIvCQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9HCK0	uniprotkb:P38340	intact:EBI-3918996|ensembl:ENSP00000362758|ensembl:ENSP00000362760|uniprotkb:B3KQ53|uniprotkb:Q8WTR1	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:zbt26_human(display_long)|uniprotkb:ZBTB26(gene name)|psi-mi:ZBTB26(display_short)|uniprotkb:KIAA1572(gene name synonym)|uniprotkb:ZNF481(gene name synonym)|uniprotkb:Zinc finger protein 481(gene name synonym)|uniprotkb:Zinc finger protein Bioref(gene name synonym)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11558278|imex:IM-24995-4712	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000171448(gene)|ensembl:ENST00000373654(transcript)|ensembl:ENST00000373656(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|refseq:NP_001291292.1|refseq:NP_001291293.1|refseq:NP_065975.1|entrezgene/locuslink:57684(identity)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	-	-	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:o5XKyl1Z7AtQOJH5HBqkYh5w1n89606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:408136B037FEA602|rigid:Ft7v8Okidfj2nRLaVFStbCWJREY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9HAN9	uniprotkb:P38340	intact:EBI-3917542|uniprotkb:Q8TAE9|uniprotkb:Q9H6B6|uniprotkb:Q9H247|uniprotkb:B1AN63|ensembl:ENSP00000366410|ensembl:ENSP00000435134	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:nmna1_human(display_long)|uniprotkb:NMNAT1(gene name)|psi-mi:NMNAT1(display_short)|uniprotkb:NMNAT(gene name synonym)|uniprotkb:Nicotinate-nucleotide adenylyltransferase 1(gene name synonym)|uniprotkb:Nicotinamide-nucleotide adenylyltransferase 1(gene name synonym)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11558269|imex:IM-24995-4711	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001284707.1|refseq:NP_073624.2|ensembl:ENSG00000173614(gene)|ensembl:ENST00000377205(transcript)|ensembl:ENST00000462686(transcript)|go:"GO:0000309"(nicotinamide-nucleotide adenylyltransferase activity)|go:"GO:0004515"(nicotinate-nucleotide adenylyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0009165"(nucleotide biosynthetic process)|go:"GO:0009435"(NAD biosynthetic process)|go:"GO:0009611"(response to wounding)|go:"GO:0016604"(nuclear body)|go:"GO:0042802"(identical protein binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:1902511"(negative regulation of apoptotic DNA fragmentation)|go:"GO:1990966"(ATP generation from poly-ADP-D-ribose)|interpro:IPR004821(Cytidyltransferase-related)|interpro:IPR005248(Probable nicotinate-nucleotide adenylyltransferase)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|mint:Q9HAN9|rcsb pdb:1GZU|rcsb pdb:1KKU|rcsb pdb:1KQN|rcsb pdb:1KQO|rcsb pdb:1KR2|reactome:R-HSA-196807|refseq:XP_016857596.1|dip:DIP-60881N|entrezgene/locuslink:64802(identity)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	-	-	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:KwV9lz04z3ptlVpKu3b534Yekpc9606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:B0198F390CA8B6B1|rigid:TsLbVS534F30ED4+TUYXBnjmJXc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38340	uniprotkb:Q9C0F1	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-744115|uniprotkb:A8K8W9|uniprotkb:B3KT53|uniprotkb:Q8IXZ4|uniprotkb:A8MW11|uniprotkb:D3DP42|ensembl:ENSP00000296519|ensembl:ENSP00000380009|ensembl:ENSP00000423153	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:cep44_human(display_long)|uniprotkb:HBV PreS1-transactivated protein 3(gene name synonym)|uniprotkb:CEP44(gene name)|psi-mi:CEP44(display_short)|uniprotkb:KIAA1712(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11558260|imex:IM-24995-4710	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	refseq:NP_001035247.1|refseq:NP_001138786.1|refseq:XP_011530587.1|refseq:XP_011530588.1|refseq:XP_011530589.1|refseq:XP_016864143.1|refseq:XP_016864144.1|ensembl:ENSG00000164118(gene)|ensembl:ENST00000296519(transcript)|ensembl:ENST00000396791(transcript)|ensembl:ENST00000503780(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007099"(centriole replication)|go:"GO:0008017"(microtubule binding)|go:"GO:0010457"(centriole-centriole cohesion)|go:"GO:0030496"(midbody)|interpro:IPR029157|interpro:IPR033603|mint:Q9C0F1|entrezgene/locuslink:80817(identity)	-	crc64:66699F37B0013088	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:gDTC64oDhudGdsssC7v+suIHZkA9606	intact-crc:DA2337BD105D6771|rigid:b9Pj/2akUY0/l21/+ZcQGgH58UM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38340	uniprotkb:Q9BYV6-2	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-11522718|ensembl:ENSP00000297348	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:q9byv6-2(display_long)|uniprotkb:TRIM55(gene name)|psi-mi:TRIM55(display_short)|uniprotkb:MURF2(gene name synonym)|uniprotkb:Muscle-specific RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 29(gene name synonym)|uniprotkb:RNF29(gene name synonym)|uniprotkb:p50(isoform synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11558251|imex:IM-24995-4709	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	intact:EBI-2341179(isoform-parent)|uniprotkb:Q9BYV6-2(isoform-parent)|ensembl:ENSG00000147573(gene)|ensembl:ENST00000353317(transcript)|entrezgene/locuslink:84675(identity)	-	crc64:66699F37B0013088	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:9t8UhK+Z1yBqjnQrOqPD76NuXGg9606	intact-crc:51ADC3FEBB5BE2D3|rigid:D6TuJ5LQQI7/fHckMWSouMivIz0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38340	uniprotkb:Q9P2A4	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-742038|uniprotkb:C9IZN8|ensembl:ENSP00000225941|uniprotkb:Q9H0P6	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:abi3_human(display_long)|uniprotkb:New molecule including SH3(gene name synonym)|uniprotkb:ABI3(gene name)|psi-mi:ABI3(display_short)|uniprotkb:NESH(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11558332|imex:IM-24995-4718	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	refseq:NP_001128658.1|refseq:NP_057512.1|ensembl:ENSG00000108798(gene)|ensembl:ENST00000225941(transcript)|go:"GO:0002357"(defense response to tumor cell)|go:"GO:0005737"(cytoplasm)|go:"GO:0010593"(negative regulation of lamellipodium assembly)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031209"(SCAR complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0051015"(actin filament binding)|go:"GO:0061001"(regulation of dendritic spine morphogenesis)|go:"GO:0099151"(regulation of postsynaptic density assembly)|go:"GO:1900028"(negative regulation of ruffle assembly)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|go:"GO:2000249"(regulation of actin cytoskeleton reorganization)|go:"GO:2000774"(positive regulation of cellular senescence)|interpro:IPR001452(Src homology-3)|interpro:IPR012849(Abl-interactor, homeo-domain homologous region)|interpro:IPR028455|interpro:IPR028457|interpro:IPR036028|mint:Q9P2A4|entrezgene/locuslink:51225(identity)	-	crc64:66699F37B0013088	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:VAjz40ulLa5L+GmfL7ia5wTDND49606	intact-crc:805723DDA0BA0DD8|rigid:ZzmrJLOHIzqscfc6FvWmLPw50F8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9NWS6	uniprotkb:P38340	intact:EBI-8638992|uniprotkb:B4DY02|ensembl:ENSP00000216214|ensembl:ENSP00000395892|intact:MINT-8162875|uniprotkb:Q5TII5|uniprotkb:B3KWG4|uniprotkb:Q96CY3	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:f118a_human(display_long)|uniprotkb:FAM118A(gene name)|psi-mi:FAM118A(display_short)|uniprotkb:C22orf8(gene name synonym)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11558323|imex:IM-24995-4717	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000100376(gene)|ensembl:ENST00000216214(transcript)|ensembl:ENST00000441876(transcript)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|interpro:IPR033353|interpro:IPR038916|interpro:IPR039444|refseq:NP_060381.2|refseq:NP_001098065.1|entrezgene/locuslink:55007(identity)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	-	comment:mint	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:zZMOyeZwAeoDNLBQ9EKYRw4+0BM9606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:0EA7F93E4AA86A84|rigid:ViXk1gZdB3sdHGkhG4tOPMJF124	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9NVV9	uniprotkb:P38340	intact:EBI-741515|uniprotkb:Q53FQ1|uniprotkb:Q6IA99|ensembl:ENSP00000254250|uniprotkb:A6NCB6|uniprotkb:D3DSY5|uniprotkb:H9KV49	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:thap1_human(display_long)|uniprotkb:THAP1(gene name)|psi-mi:THAP1(display_short)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11558314|imex:IM-24995-4716	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060575.1|ensembl:ENSG00000131931(gene)|ensembl:ENST00000254250(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001650"(fibrillar center)|go:"GO:0001935"(endothelial cell proliferation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007049"(cell cycle)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016605"(PML body)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR006612(Zinc finger, C2CH-type)|interpro:IPR026516|interpro:IPR038441|mint:Q9NVV9|rcsb pdb:2JTG|rcsb pdb:2KO0|rcsb pdb:2L1G|refseq:NP_945354.1|entrezgene/locuslink:55145(identity)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	-	-	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:/KO90pu5tBnIVq9SMx1JYPXFCEQ9606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:3D86D8B4391CFCDE|rigid:nXSsDqXxvAuQuiN3QMDBNnUTHxk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9NSC5	uniprotkb:P38340	intact:EBI-748420|uniprotkb:O14580|uniprotkb:O95350|uniprotkb:Q9NSB9|uniprotkb:Q9NSC0|intact:EBI-2557809|uniprotkb:E9PCW9|uniprotkb:Q9NSC1|intact:EBI-28972925|ensembl:ENSP00000376162|ensembl:ENSP00000439937|ensembl:ENSP00000446026|intact:EBI-10175777|uniprotkb:B2RA10	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:home3_human(display_long)|uniprotkb:HOMER3(gene name)|psi-mi:HOMER3(display_short)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11558305|imex:IM-24995-4715	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000221222|ensembl:ENSP00000221222|ensembl:ENSP00000376162|ensembl:ENST00000433218|ensembl:ENSP00000396154|ensembl:ENSP00000439937|ensembl:ENSP00000446026|ensembl:ENST00000594439|ensembl:ENSP00000471835|refseq:XP_006723006.1|refseq:XP_006723007.1|refseq:NP_001139193.1|refseq:NP_001139194.1|refseq:NP_004829.3|refseq:NP_001139196.1|ensembl:ENSG00000051128(gene)|ensembl:ENST00000392351(transcript)|ensembl:ENST00000539827(transcript)|ensembl:ENST00000542541(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006605"(protein targeting)|go:"GO:0007216"(G protein-coupled glutamate receptor signaling pathway)|go:"GO:0014069"(postsynaptic density)|go:"GO:0030425"(dendrite)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0035256"(G protein-coupled glutamate receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|go:"GO:2001256"(regulation of store-operated calcium entry)|interpro:IPR000697(EVH1)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR044100|mint:Q9NSC5|rcsb pdb:2P8V|rcsb pdb:3CVF|reactome:R-HSA-6794361|entrezgene/locuslink:9454(identity)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	-	-	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:U1y/y52nnf7zQUCNQlqk7JDgXi49606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:F139A5D9AE9B2AE0|rigid:MadKq7FrrRQ7KphkPSb9mHcWQFQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9NRY6	uniprotkb:P38340	intact:EBI-750734|uniprotkb:Q567U0|uniprotkb:Q8NBW6|uniprotkb:Q96F13|uniprotkb:A8K252|ensembl:ENSP00000316021|ensembl:ENSP00000459019|ensembl:ENSP00000459419|ensembl:ENSP00000491350|ensembl:ENSP00000491393|ensembl:ENSP00000492026|ensembl:ENSP00000492083|ensembl:ENSP00000483743	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:pls3_human(display_long)|uniprotkb:"Ca(2+)-dependent phospholipid scramblase 3"(gene name synonym)|uniprotkb:PLSCR3(gene name)|psi-mi:PLSCR3(display_short)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11558296|imex:IM-24995-4714	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001188505.1|refseq:NP_065093.2|ensembl:ENSG00000187838(gene)|ensembl:ENSG00000284009(gene)|ensembl:ENST00000324822(transcript)|ensembl:ENST00000574401(transcript)|ensembl:ENST00000576201(transcript)|ensembl:ENST00000619711(transcript)|ensembl:ENST00000639780(transcript)|ensembl:ENST00000639874(transcript)|ensembl:ENST00000640053(transcript)|ensembl:ENST00000640375(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017121"(plasma membrane phospholipid scrambling)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0017128"(phospholipid scramblase activity)|go:"GO:0032049"(cardiolipin biosynthetic process)|go:"GO:0032791"(lead ion binding)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043621"(protein self-association)|go:"GO:0045340"(mercury ion binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0090199"(regulation of release of cytochrome c from mitochondria)|interpro:IPR005552(Scramblase)|entrezgene/locuslink:57048(identity)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	-	-	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:JKzacFCwrCQpcI3EJsLvpAbLFCA9606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:7970EA689B836812|rigid:kYHWB6acjNUbKK6TPDe1djT2Fc0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UHX1-5	uniprotkb:P38340	intact:EBI-11526420|ensembl:ENSP00000395417|ensembl:ENSP00000478209	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:q9uhx1-5(display_long)|uniprotkb:PUF60(gene name)|psi-mi:PUF60(display_short)|uniprotkb:"60 kDa poly(U)-binding-splicing factor"(gene name synonym)|uniprotkb:FIR(gene name synonym)|uniprotkb:FUSE-binding protein-interacting repressor(gene name synonym)|uniprotkb:ROBPI(gene name synonym)|uniprotkb:Ro-binding protein 1(gene name synonym)|uniprotkb:SIAHBP1(gene name synonym)|uniprotkb:Siah-binding protein 1(gene name synonym)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11558359|imex:IM-24995-4721	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-1053259(isoform-parent)|ensembl:ENSG00000179950(gene)|ensembl:ENSG00000274081(gene)|ensembl:ENST00000456095(transcript)|ensembl:ENST00000620953(transcript)|entrezgene/locuslink:22827(identity)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	-	isoform-comment:"Contains a glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) at position 14."	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:PSbIU++DIL6ysF0ccd3ZHzeJ5rs9606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:CDA44E5BE523A184|rigid:arMDTNRejdWEm+w41YUmN6muyD8	false	sufficient binding region:15-530	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UHX1-2	uniprotkb:P38340	intact:EBI-11529177|ensembl:ENSP00000322036|ensembl:ENSP00000478495	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:q9uhx1-2(display_long)|uniprotkb:PUF60(gene name)|psi-mi:PUF60(display_short)|uniprotkb:"60 kDa poly(U)-binding-splicing factor"(gene name synonym)|uniprotkb:FIR(gene name synonym)|uniprotkb:FUSE-binding protein-interacting repressor(gene name synonym)|uniprotkb:ROBPI(gene name synonym)|uniprotkb:Ro-binding protein 1(gene name synonym)|uniprotkb:SIAHBP1(gene name synonym)|uniprotkb:Siah-binding protein 1(gene name synonym)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11558350|imex:IM-24995-4720	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-1053259(isoform-parent)|ensembl:ENSG00000179950(gene)|ensembl:ENSG00000274081(gene)|ensembl:ENST00000349157(transcript)|ensembl:ENST00000612237(transcript)|uniprotkb:Q9UHX1-2(isoform-parent)|entrezgene/locuslink:22827(identity)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	-	-	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:snVN9Lw5+MP2/aiq4z08ANwvr209606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:894796C00E898BAC|rigid:9yjNEVIDBi5WlCsKOQdzJS9UL3I	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38340	uniprotkb:Q9UDV6	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-1640204|uniprotkb:Q13396|uniprotkb:Q8N664|uniprotkb:B2RCF4|ensembl:ENSP00000338572	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:zn212_human(display_long)|uniprotkb:ZNF212(gene name)|psi-mi:ZNF212(display_short)|uniprotkb:ZNFC150(gene name synonym)|uniprotkb:Zinc finger protein C2H2-150(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11558341|imex:IM-24995-4719	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	refseq:NP_036388.2|ensembl:ENSG00000170260(gene)|ensembl:ENST00000335870(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR022137|interpro:IPR036051|interpro:IPR036236|mint:Q9UDV6|reactome:R-HSA-212436|entrezgene/locuslink:7988(identity)	-	crc64:66699F37B0013088	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:jZtScr5t/MR83+d1tdA9OiP4JCA9606	intact-crc:4DC5556553A98BE6|rigid:qXq1mnyZehMkMSTEz8juyKSjq8E	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9Y2D8	uniprotkb:P38340	intact:EBI-2212028|uniprotkb:B4DFE3|uniprotkb:J3KR02|uniprotkb:A8K8W0|uniprotkb:D3DT13|uniprotkb:Q6P2P8|uniprotkb:Q6ULS1|uniprotkb:Q7L168|uniprotkb:Q9UIX0|intact:EBI-10964529|ensembl:ENSP00000340279	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:adip_human(display_long)|uniprotkb:SSX2IP(gene name)|psi-mi:SSX2IP(display_short)|uniprotkb:KIAA0923(gene name synonym)|uniprotkb:Afadin DIL domain-interacting protein(gene name synonym)|uniprotkb:SSX2-interacting protein(gene name synonym)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11558408|imex:IM-24995-4726	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011538912.1|refseq:NP_001159765.1|refseq:NP_001159766.1|refseq:NP_001159767.1|refseq:NP_001159889.1|refseq:NP_054740.3|refseq:XP_005270484.1|refseq:XP_005270485.1|refseq:XP_006710394.1|refseq:XP_016855723.1|ensembl:ENSG00000117155(gene)|ensembl:ENST00000342203(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005912"(adherens junction)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031252"(cell leading edge)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0035735"(intraciliary transport involved in cilium assembly)|go:"GO:0036064"(ciliary basal body)|go:"GO:0060271"(cilium assembly)|go:"GO:2000145"(regulation of cell motility)|interpro:IPR021622|mint:Q9Y2D8|entrezgene/locuslink:117178(identity)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	-	-	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:E0VeMRF9SrpQKSJFP01XEbMjeF89606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:E394BE69FF530D7D|rigid:6qAMXpSLuBuvHe7iirMVkcK0K8o	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38340	uniprotkb:Q9Y281	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-351218|uniprotkb:G3V5P4|ensembl:ENSP00000298159|ensembl:ENSP00000340635|ensembl:ENSP00000500375|ensembl:ENSP00000500532	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:cof2_human(display_long)|uniprotkb:CFL2(gene name)|psi-mi:CFL2(display_short)|uniprotkb:Cofilin, muscle isoform(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11558399|imex:IM-24995-4725	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	refseq:NP_068733.1|refseq:NP_619579.1|refseq:XP_011534665.1|refseq:NP_001230574.1|dip:DIP-33178N|ensembl:ENSG00000165410(gene)|ensembl:ENST00000298159(transcript)|ensembl:ENST00000341223(transcript)|ensembl:ENST00000672163(transcript)|ensembl:ENST00000672517(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016363"(nuclear matrix)|go:"GO:0030018"(Z disc)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030043"(actin filament fragmentation)|go:"GO:0030836"(positive regulation of actin filament depolymerization)|go:"GO:0031674"(I band)|go:"GO:0045214"(sarcomere organization)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0048870"(cell motility)|go:"GO:0051014"(actin filament severing)|go:"GO:0051015"(actin filament binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002108(Actin-binding, cofilin/tropomyosin type)|interpro:IPR017904|interpro:IPR029006|mint:Q9Y281|entrezgene/locuslink:1073(identity)	-	crc64:66699F37B0013088	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:HwYoUPZRkuRzqMLvuQctwNCOREA9606	intact-crc:17C43B20FE9FF89A|rigid:dkDxg6oyNPMCnLXoGQkGZlDBp1E	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9ULA0	uniprotkb:P38340	intact:EBI-748356|uniprotkb:Q9BW44|uniprotkb:Q9NUV5|uniprotkb:Q9NV55|ensembl:ENSP00000273075	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:dnpep_human(display_long)|uniprotkb:ASPEP(gene name synonym)|uniprotkb:DAP(gene name synonym)|uniprotkb:DNPEP(gene name)|psi-mi:DNPEP(display_short)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11558390|imex:IM-24995-4724	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306049.1|refseq:NP_036232.2|ensembl:ENSG00000123992(gene)|ensembl:ENST00000273075(transcript)|go:"GO:0004177"(aminopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006518"(peptide metabolic process)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0072562"(blood microparticle)|interpro:IPR001948(Peptidase M18, aminopeptidase I)|interpro:IPR023358|rcsb pdb:4DYO|entrezgene/locuslink:23549(identity)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	-	-	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2020/10/21	rogid:xG06vZosglPmA5ktZd8A8EH9h0g9606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:C7709B24FB66393E|rigid:Fp77wJo8+HbRZpyPHuZBtGTjUXA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UI14	uniprotkb:P38340	intact:EBI-712367|ensembl:ENSP00000222008|uniprotkb:Q7Z4Y2|uniprotkb:Q9Y3R1	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:praf1_human(display_long)|uniprotkb:PRA1 family protein 1(gene name synonym)|uniprotkb:RABAC1(gene name)|psi-mi:RABAC1(display_short)|uniprotkb:PRA1(gene name synonym)|uniprotkb:PRAF1(gene name synonym)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11558381|imex:IM-24995-4723	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006414.2|ensembl:ENSG00000105404(gene)|ensembl:ENST00000222008(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0070064"(proline-rich region binding)|interpro:IPR004895(Prenylated rab acceptor PRA1)|mint:Q9UI14|entrezgene/locuslink:10567(identity)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	-	-	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:WS2rUY7yXRbR7pqWgfUCbnEiDbg9606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:88E10B0139108260|rigid:BK1n3/d6sldlD+wVYtMoikRhz2E	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UHX1-6	uniprotkb:P38340	intact:EBI-11085298|ensembl:ENSP00000431960	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:q9uhx1-6(display_long)|uniprotkb:PUF60(gene name)|psi-mi:PUF60(display_short)|uniprotkb:"60 kDa poly(U)-binding-splicing factor"(gene name synonym)|uniprotkb:FIR(gene name synonym)|uniprotkb:FUSE-binding protein-interacting repressor(gene name synonym)|uniprotkb:ROBPI(gene name synonym)|uniprotkb:Ro-binding protein 1(gene name synonym)|uniprotkb:SIAHBP1(gene name synonym)|uniprotkb:Siah-binding protein 1(gene name synonym)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11558370|imex:IM-24995-4722	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000179950(gene)|ensembl:ENST00000527197(transcript)|intact:EBI-1053259(isoform-parent)|uniprotkb:Q9UHX1-6(isoform-parent)|entrezgene/locuslink:22827(identity)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	-	isoform-comment:"Contains a glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) at position 14."	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:rSsTImwmpEAWMCxLzF5Y4zVdeFM9606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:5BC13584840D798B|rigid:AGw+HnxGbnqrYFDQxeuC0bO441g	false	sufficient binding region:15-513	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q99259	uniprotkb:P38635	intact:EBI-743184|ensembl:ENSP00000350928|uniprotkb:Q53TQ7|uniprotkb:Q9BU91|uniprotkb:Q9UHH4|uniprotkb:Q49AK1	intact:EBI-2045554|uniprotkb:D6VTQ5|ensemblfungi:YFR025C	psi-mi:dce1_human(display_long)|uniprotkb:Glutamate decarboxylase 67 kDa isoform(gene name synonym)|uniprotkb:67 kDa glutamic acid decarboxylase(gene name synonym)|uniprotkb:GAD1(gene name)|psi-mi:GAD1(display_short)|uniprotkb:GAD(gene name synonym)|uniprotkb:GAD67(gene name synonym)	psi-mi:his9_yeast(display_long)|uniprotkb:YFR025C(locus name)|uniprotkb:HIS2(gene name)|psi-mi:HIS2(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11558446|imex:IM-24995-4730	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000808.2|refseq:NP_038473.2|ensembl:ENSG00000128683(gene)|ensembl:ENST00000358196(transcript)|go:"GO:0004351"(glutamate decarboxylase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0060077"(inhibitory synapse)|go:"GO:0061202"(clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006538"(glutamate catabolic process)|go:"GO:0006540"(glutamate decarboxylation to succinate)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0009449"(gamma-aminobutyric acid biosynthetic process)|go:"GO:0012506"(vesicle membrane)|go:"GO:0016595"(glutamate binding)|go:"GO:0018352"(protein-pyridoxal-5-phosphate linkage)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0035176"(social behavior)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0042136"(neurotransmitter biosynthetic process)|go:"GO:0042493"|go:"GO:0043679"(axon terminus)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048786"(presynaptic active zone)|interpro:IPR002129(Pyridoxal phosphate-dependent decarboxylase)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR021115|mint:Q99259|rcsb pdb:2OKJ|rcsb pdb:3VP6|reactome:R-HSA-888568|reactome:R-HSA-888590|reactome:R-HSA-9022927|refseq:XP_011509224.1|refseq:XP_005246501.1|refseq:XP_016859245.1|refseq:XP_016859247.1|dip:DIP-29292N|entrezgene/locuslink:2571(identity)	refseq:NP_116681.1|sgd:S000001921|interpro:IPR010140(Histidinol phosphate phosphatase, HisJ)|interpro:IPR004013(PHP, C-terminal)|interpro:IPR016195(Polymerase and histidinol phosphatase-like)|mint:P38635|ensemblfungi:YFR025C(gene)|ensemblfungi:YFR025C_mRNA(transcript)|go:"GO:0000105"(histidine biosynthetic process)|go:"GO:0004401"(histidinol-phosphatase activity)|go:"GO:0005737"(cytoplasm)|sgd:YFR025C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:tFlqx11D9m3HofJUdpZynm2jKIQ9606	rogid:3gGqFDbJWtM4it1O4HJjk6KoTL4559292	intact-crc:9347CA380BA39E69|rigid:RPeVitSwH4UGTGHiXyA/r5yXpQU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38635	uniprotkb:Q8NF64	intact:EBI-2045554|uniprotkb:D6VTQ5|ensemblfungi:YFR025C	intact:EBI-745786|uniprotkb:O94790|uniprotkb:Q0VGB4|uniprotkb:Q659A8|uniprotkb:Q6JKL5|uniprotkb:Q8WTX8|uniprotkb:Q96Q01|uniprotkb:Q9BQH7|uniprotkb:A4D2K7|uniprotkb:D3DVL1|intact:EBI-28976701|ensembl:ENSP00000311778|ensembl:ENSP00000414723	psi-mi:his9_yeast(display_long)|uniprotkb:YFR025C(locus name)|uniprotkb:HIS2(gene name)|psi-mi:HIS2(display_short)	psi-mi:zmiz2_human(display_long)|uniprotkb:PIAS-like protein Zimp7(gene name synonym)|uniprotkb:ZMIZ2(gene name)|psi-mi:ZMIZ2(display_short)|uniprotkb:KIAA1886(gene name synonym)|uniprotkb:HRIHFB2007(orf name)|uniprotkb:ZIMP7(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11558435|imex:IM-24995-4729	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_116681.1|sgd:S000001921|interpro:IPR010140(Histidinol phosphate phosphatase, HisJ)|interpro:IPR004013(PHP, C-terminal)|interpro:IPR016195(Polymerase and histidinol phosphatase-like)|mint:P38635|ensemblfungi:YFR025C(gene)|ensemblfungi:YFR025C_mRNA(transcript)|go:"GO:0000105"(histidine biosynthetic process)|go:"GO:0004401"(histidinol-phosphatase activity)|go:"GO:0005737"(cytoplasm)|sgd:YFR025C(identity)	refseq:NP_113637.3|refseq:NP_777589.2|ensembl:ENST00000265346|ensembl:ENSP00000265346|ensembl:ENSP00000311778|ensembl:ENST00000413916|ensembl:ENSP00000409648|ensembl:ENSP00000414723|refseq:NP_001287888.1|ensembl:ENSG00000122515(gene)|ensembl:ENST00000309315(transcript)|ensembl:ENST00000441627(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048096"|interpro:IPR004181(Zinc finger, MIZ-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|refseq:XP_005249926.1|refseq:XP_005249929.1|entrezgene/locuslink:83637(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:3gGqFDbJWtM4it1O4HJjk6KoTL4559292	rogid:gkO57EyOLACt/8WYxFQbasiqRro9606	intact-crc:581307CDA9098AD7|rigid:BOZGMKK7jJJWJv9E7l0s2M5uWlo	false	-	sufficient binding region:479-920	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96BA8	uniprotkb:P38374	intact:EBI-6942903|ensembl:ENSP00000481956|intact:MINT-268046|intact:MINT-8162577|uniprotkb:Q8N2D5|uniprotkb:Q96CP0	intact:EBI-29585|uniprotkb:D6VQF8|ensemblfungi:YBR162W-A	psi-mi:cr3l1_human(display_long)|uniprotkb:CREB3L1(gene name)|psi-mi:CREB3L1(display_short)|uniprotkb:OASIS(gene name synonym)|uniprotkb:PSEC0238(orf name)|uniprotkb:Old astrocyte specifically-induced substance(gene name synonym)	psi-mi:ysy6_yeast(display_long)|uniprotkb:YSY6(gene name)|psi-mi:YSY6(display_short)|uniprotkb:YBR162BW(orf name)|uniprotkb:YBR162W-A(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11558426|imex:IM-24995-4728	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157613(gene)|ensembl:ENST00000621158(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0070278"(extracellular matrix constituent secretion)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029805|mint:Q96BA8|reactome:R-HSA-8874211|refseq:NP_443086.1|entrezgene/locuslink:90993(identity)	sgd:S000002158|refseq:NP_009721.1|dip:DIP-4936N|reactome:R-SCE-9609523|ensemblfungi:YBR162W-A(gene)|ensemblfungi:YBR162W-A_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006486"(protein glycosylation)|go:"GO:0009306"(protein secretion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|interpro:IPR010580(Ribosome associated membrane RAMP4)|sgd:YBR162W-A(identity)	-	comment:mint|function:"Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE"	crc64:326410AB4772B33D	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:sMWUFmBeBBCO+T0Y2CuB/un1lBg9606	rogid:FwDeAMLCEaMmEgCDK1xjQS4MDFg559292	intact-crc:47F861E5D998C406|rigid:wrj9U3bRG1qZzkdHsBORIH0Q+2s	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9Y371	uniprotkb:P38340	intact:EBI-2623095|uniprotkb:Q9H3Z0|uniprotkb:Q9NYA9|uniprotkb:Q9NR47|uniprotkb:Q5H8U5|ensembl:ENSP00000473267|uniprotkb:B4E182	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:shlb1_human(display_long)|uniprotkb:KIAA0491(gene name synonym)|uniprotkb:Bax-interacting factor 1(gene name synonym)|uniprotkb:SH3 domain-containing GRB2-like protein B1(gene name synonym)|uniprotkb:CGI-61(orf name)|uniprotkb:SH3GLB1(gene name)|psi-mi:SH3GLB1(display_short)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11558417|imex:IM-24995-4727	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001193580.1|refseq:NP_001193581.1|refseq:NP_057093.1|go:"GO:0030496"(midbody)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032801"(receptor catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0048102"(autophagic cell death)|go:"GO:0090148"(membrane fission)|go:"GO:1903527"(positive regulation of membrane tubulation)|go:"GO:1903778"(protein localization to vacuolar membrane)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|go:"GO:2000786"(positive regulation of autophagosome assembly)|interpro:IPR001452(Src homology-3)|interpro:IPR004148(BAR)|interpro:IPR027267|interpro:IPR028503|interpro:IPR035695|interpro:IPR036028|mint:Q9Y371|rcsb pdb:6UP6|rcsb pdb:6UPN|ensembl:ENSG00000097033(gene)|ensembl:ENST00000370558(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0006915"(apoptotic process)|go:"GO:0008289"(lipid binding)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016241"(regulation of macroautophagy)|refseq:NP_001193582.1|dip:DIP-41970N|entrezgene/locuslink:51100(identity)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F|sgd:YBR261C(identity)	-	-	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:HSs455W45ciZL56fJSPOIvfhUIw9606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:652A08D17AE1CD3A|rigid:y/esqv3+RMBW2Zk3eJGXwnsBAZ0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38432	uniprotkb:P38732	intact:EBI-945751|uniprotkb:B2R931|ensembl:ENSP00000240316	intact:EBI-24379|uniprotkb:D3DKT0|ensemblfungi:YHL039W	psi-mi:coil_human(display_long)|uniprotkb:COIL(gene name)|psi-mi:COIL(display_short)|uniprotkb:CLN80(gene name synonym)|uniprotkb:p80-coilin(gene name synonym)	psi-mi:efm1_yeast(display_long)|uniprotkb:EFM1(gene name)|psi-mi:EFM1(display_short)|uniprotkb:Elongation factor methyltransferase 1(gene name synonym)|uniprotkb:YHL039W(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11558492|imex:IM-24995-4735	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004636.1|dip:DIP-38503N|ensembl:ENSG00000121058(gene)|ensembl:ENST00000240316(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0015030"(Cajal body)|go:"GO:0016020"(membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0030619"(U1 snRNA binding)|go:"GO:0030620"(U2 snRNA binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR024822|interpro:IPR031722|mint:P38432|entrezgene/locuslink:8161(identity)	refseq:NP_011824.1|sgd:S000001031|dip:DIP-6582N|mint:P38732|ensemblfungi:YHL039W(gene)|ensemblfungi:YHL039W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0018026"(peptidyl-lysine monomethylation)|go:"GO:0018027"(peptidyl-lysine dimethylation)|interpro:IPR001214(SET)|interpro:IPR017119(Ribosomal lysine methyltransferase 1)|interpro:IPR044432|sgd:YHL039W(identity)	-	-	crc64:84BC2D3A204D9D29	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:hd5p6AbyA/GYNEeca99Mdb41qM09606	rogid:e5E4ijHZAIzzKWrxCzPqifR2v8U559292	intact-crc:05BA031C254FC07D|rigid:g8DjAPiY7s/Ez4qEL6eO+HZ0ojI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O75569	uniprotkb:P38732	intact:EBI-713955|ensembl:ENSP00000318176|uniprotkb:Q53G24|uniprotkb:Q6X7T5|uniprotkb:Q8NDK4|uniprotkb:A8K3I6	intact:EBI-24379|uniprotkb:D3DKT0|ensemblfungi:YHL039W	psi-mi:prkra_human(display_long)|uniprotkb:Protein activator of the interferon-induced protein kinase(gene name synonym)|uniprotkb:PKR-associated protein X(gene name synonym)|uniprotkb:PKR-associating protein X(gene name synonym)|uniprotkb:HSD-14(orf name)|uniprotkb:PRKRA(gene name)|psi-mi:PRKRA(display_short)|uniprotkb:RAX(gene name synonym)|uniprotkb:PACT(gene name synonym)|uniprotkb:HSD14(orf name)|uniprotkb:Protein kinase, interferon-inducible double-stranded RNA-dependent activator(gene name synonym)	psi-mi:efm1_yeast(display_long)|uniprotkb:EFM1(gene name)|psi-mi:EFM1(display_short)|uniprotkb:Elongation factor methyltransferase 1(gene name synonym)|uniprotkb:YHL039W(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11558483|imex:IM-24995-4734	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006955"(immune response)|go:"GO:0008047"(enzyme activator activity)|ensembl:ENSG00000180228(gene)|ensembl:ENST00000325748(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030422"(production of siRNA involved in RNA interference)|go:"GO:0031054"(pre-miRNA processing)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035196"(production of miRNAs involved in gene silencing by miRNA)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042474"(middle ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:0050821"(protein stabilization)|go:"GO:0070578"(RISC-loading complex)|go:"GO:0070883"(pre-miRNA binding)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR032478|interpro:IPR033363|interpro:IPR044465|interpro:IPR044466|interpro:IPR044467|mint:O75569|rcsb pdb:2DIX|reactome:R-HSA-203927|reactome:R-HSA-426486|refseq:NP_001132989.1|refseq:NP_001132990.1|refseq:NP_003681.1|dip:DIP-41809N|entrezgene/locuslink:8575(identity)	refseq:NP_011824.1|sgd:S000001031|dip:DIP-6582N|mint:P38732|ensemblfungi:YHL039W(gene)|ensemblfungi:YHL039W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0018026"(peptidyl-lysine monomethylation)|go:"GO:0018027"(peptidyl-lysine dimethylation)|interpro:IPR001214(SET)|interpro:IPR017119(Ribosomal lysine methyltransferase 1)|interpro:IPR044432|sgd:YHL039W(identity)	-	-	crc64:84BC2D3A204D9D29	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:tZfziopZlC+1d3De97G3kDY+Tog9606	rogid:e5E4ijHZAIzzKWrxCzPqifR2v8U559292	intact-crc:425FF1BA4E369CDA|rigid:a/LTA+bxGClszC704i1ljQY/RaQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38703	uniprotkb:P63279	intact:EBI-10035|uniprotkb:Q6LD26|uniprotkb:D3DKR1|ensemblfungi:YHL003C	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	psi-mi:lag1_yeast(display_long)|uniprotkb:LAG1(gene name)|psi-mi:LAG1(display_short)|uniprotkb:Longevity assurance factor 1(gene name synonym)|uniprotkb:Longevity assurance protein 1(gene name synonym)|uniprotkb:Longevity assurance gene 1 protein(gene name synonym)|uniprotkb:Very-long-chain ceramide synthase LAG1(gene name synonym)|uniprotkb:YHL003C(locus name)	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11558474|imex:IM-24995-4733	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011860.1|sgd:S000000995|ensemblfungi:YHL003C(gene)|ensemblfungi:YHL003C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016410"(N-acyltransferase activity)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:0050291"(sphingosine N-acyltransferase activity)|go:"GO:0061576"(acyl-CoA ceramide synthase complex)|interpro:IPR006634(TRAM, LAG1 and CLN8 homology)|interpro:IPR013599(TRAM1-like protein)|interpro:IPR016439(Longevity assurance, LAG1/LAC1)|reactome:R-SCE-1660661|dip:DIP-4393N|mint:P38703|sgd:YHL003C(identity)	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N|entrezgene/locuslink:7329(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:KCAjx/gXmy0oGd3aKgasDuFHJzw559292	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	intact-crc:B773939D5CBD5FA3|rigid:GzR5EKIvbhutmOl+4ZPKiZuCbPE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96BA8	uniprotkb:P38695	intact:EBI-6942903|ensembl:ENSP00000481956|intact:MINT-268046|intact:MINT-8162577|uniprotkb:Q8N2D5|uniprotkb:Q96CP0	intact:EBI-8778|ensemblfungi:YHR096C|uniprotkb:D3DL46	psi-mi:cr3l1_human(display_long)|uniprotkb:CREB3L1(gene name)|psi-mi:CREB3L1(display_short)|uniprotkb:OASIS(gene name synonym)|uniprotkb:PSEC0238(orf name)|uniprotkb:Old astrocyte specifically-induced substance(gene name synonym)	psi-mi:hxt5_yeast(display_long)|uniprotkb:YHR096C(locus name)|uniprotkb:HXT5(gene name)|psi-mi:HXT5(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11558464|imex:IM-24995-4732	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157613(gene)|ensembl:ENST00000621158(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0070278"(extracellular matrix constituent secretion)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029805|mint:Q96BA8|reactome:R-HSA-8874211|refseq:NP_443086.1|entrezgene/locuslink:90993(identity)	ensemblfungi:YHR096C(gene)|ensemblfungi:YHR096C_mRNA(transcript)|go:"GO:0005351"("carbohydrate:proton symporter activity")|go:"GO:0005355"(glucose transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005353"(fructose transmembrane transporter activity)|go:"GO:0008643"(carbohydrate transport)|go:"GO:0008645"(hexose transmembrane transport)|go:"GO:0015578"(mannose transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|go:"GO:1904659"(glucose transmembrane transport)|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259|refseq:NP_011964.1|sgd:S000001138|mint:P38695|dip:DIP-5594N|sgd:YHR096C(identity)	-	comment:mint|function:"Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE"	crc64:6906721BAC1A5F87	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:sMWUFmBeBBCO+T0Y2CuB/un1lBg9606	rogid:aZGrWmUu+AZ4G6qmTG+Z+p6i7hs559292	intact-crc:7FD0623E9D8628E8|rigid:clZKqOoiykAaQU0HwL5bwgX/Tt0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8N6L0	uniprotkb:P38695	intact:EBI-749265|uniprotkb:Q96MC3|ensembl:ENSP00000404220	intact:EBI-8778|ensemblfungi:YHR096C|uniprotkb:D3DL46	psi-mi:kash5_human(display_long)|uniprotkb:KASH5(gene name)|psi-mi:KASH5(display_short)|uniprotkb:CCDC155(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 155(gene name synonym)|uniprotkb:KASH domain-containing protein 5(gene name synonym)	psi-mi:hxt5_yeast(display_long)|uniprotkb:YHR096C(locus name)|uniprotkb:HXT5(gene name)|psi-mi:HXT5(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11558455|imex:IM-24995-4731	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_653289.3|ensembl:ENSG00000161609(gene)|ensembl:ENST00000447857(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034397"(telomere localization)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051225"(spindle assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0090172"(microtubule cytoskeleton organization involved in homologous chromosome segregation)|go:"GO:0090220"(chromosome localization to nuclear envelope involved in homologous chromosome segregation)|go:"GO:0090619"(meiotic spindle pole)|interpro:IPR011992(EF-Hand type)|interpro:IPR028168|interpro:IPR028170|interpro:IPR039508|mint:Q8N6L0|rcsb pdb:6R2I|rcsb pdb:6WMF|entrezgene/locuslink:147872(identity)	ensemblfungi:YHR096C(gene)|ensemblfungi:YHR096C_mRNA(transcript)|go:"GO:0005351"("carbohydrate:proton symporter activity")|go:"GO:0005355"(glucose transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005353"(fructose transmembrane transporter activity)|go:"GO:0008643"(carbohydrate transport)|go:"GO:0008645"(hexose transmembrane transport)|go:"GO:0015578"(mannose transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|go:"GO:1904659"(glucose transmembrane transport)|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259|refseq:NP_011964.1|sgd:S000001138|mint:P38695|dip:DIP-5594N|sgd:YHR096C(identity)	-	-	crc64:6906721BAC1A5F87	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Wl9L7AcvDHCZuKjYLn8QgGIbZTc9606	rogid:aZGrWmUu+AZ4G6qmTG+Z+p6i7hs559292	intact-crc:E41B8311AE78881B|rigid:t8lYMWTXrz7eoxfyij3jYiVMNaM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38744	uniprotkb:O76083-2	intact:EBI-13396|uniprotkb:D3DKR5|ensemblfungi:YHL018W	intact:EBI-11524542|ensembl:ENSP00000335242	psi-mi:phs_yeast(display_long)|uniprotkb:4-alpha-hydroxy-tetrahydropterin dehydratase(gene name synonym)|uniprotkb:Pterin carbinolamine dehydratase(gene name synonym)|uniprotkb:YHL018W(locus name)	psi-mi:o76083-2(display_long)|uniprotkb:PDE9A(gene name)|psi-mi:PDE9A(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11558546|imex:IM-24995-4741	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011845.1|sgd:S000001010|interpro:IPR036428|interpro:IPR001533(Transcriptional coactivator/pterin dehydratase)|ensemblfungi:YHL018W(gene)|ensemblfungi:YHL018W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0008124"(4-alpha-hydroxytetrahydrobiopterin dehydratase activity)|dip:DIP-1872N|reactome:R-SCE-8964208|sgd:YHL018W(identity)	intact:EBI-742764(isoform-parent)|ensembl:ENSG00000160191(gene)|ensembl:ENST00000335512(transcript)|uniprotkb:O76083-2(isoform-parent)|entrezgene/locuslink:5152(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:7+JuLX1wFw/tkE4NcSCTK62b4DU559292	rogid:nTzgeYGOwTM/7VJUgxSnlnDiCFo9606	intact-crc:AE03350182639A24|rigid:SeKXelifYejMqVdZovbthoJLm68	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96BA8	uniprotkb:P38736	intact:EBI-6942903|ensembl:ENSP00000481956|intact:MINT-268046|intact:MINT-8162577|uniprotkb:Q8N2D5|uniprotkb:Q96CP0	intact:EBI-24365|uniprotkb:D3DKT7|ensemblfungi:YHL031C	psi-mi:cr3l1_human(display_long)|uniprotkb:CREB3L1(gene name)|psi-mi:CREB3L1(display_short)|uniprotkb:OASIS(gene name synonym)|uniprotkb:PSEC0238(orf name)|uniprotkb:Old astrocyte specifically-induced substance(gene name synonym)	psi-mi:gosr1_yeast(display_long)|uniprotkb:Golgi SNARE protein 1(gene name synonym)|uniprotkb:GOS1(gene name)|psi-mi:GOS1(display_short)|uniprotkb:Protein transport protein GOS1(gene name synonym)|uniprotkb:YHL031C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11558537|imex:IM-24995-4740	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157613(gene)|ensembl:ENST00000621158(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0070278"(extracellular matrix constituent secretion)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029805|mint:Q96BA8|reactome:R-HSA-8874211|refseq:NP_443086.1|entrezgene/locuslink:90993(identity)	refseq:NP_011832.1|sgd:S000001023|reactome:R-SCE-6811438|dip:DIP-2490N|reactome:R-SCE-6807878|ensemblfungi:YHL031C(gene)|ensemblfungi:YHL031C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005797"(Golgi medial cisterna)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0048193"(Golgi vesicle transport)|go:"GO:0048209"(regulation of vesicle targeting, to, from or within Golgi)|interpro:IPR023601|go:"GO:0006906"(vesicle fusion)|sgd:YHL031C(identity)	-	comment:mint|function:"Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE"	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:sMWUFmBeBBCO+T0Y2CuB/un1lBg9606	rogid:pAzDzV46XXzIOB4p/oc1PlMc54E559292	intact-crc:B62871945C136344|rigid:nyLw3FZJsmx2KHNyGUz8o3CuFSk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8WW34-2	uniprotkb:P38736	intact:EBI-11528917|ensembl:ENSP00000369959	intact:EBI-24365|uniprotkb:D3DKT7|ensemblfungi:YHL031C	psi-mi:q8ww34-2(display_long)|uniprotkb:TMEM239(gene name)|psi-mi:TMEM239(display_short)	psi-mi:gosr1_yeast(display_long)|uniprotkb:Golgi SNARE protein 1(gene name synonym)|uniprotkb:GOS1(gene name)|psi-mi:GOS1(display_short)|uniprotkb:Protein transport protein GOS1(gene name synonym)|uniprotkb:YHL031C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11558528|imex:IM-24995-4739	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-9675724(isoform-parent)|uniprotkb:Q8WW34-2(isoform-parent)|ensembl:ENSG00000198326(gene)|ensembl:ENST00000380585(transcript)|entrezgene/locuslink:100288797(identity)	refseq:NP_011832.1|sgd:S000001023|reactome:R-SCE-6811438|dip:DIP-2490N|reactome:R-SCE-6807878|ensemblfungi:YHL031C(gene)|ensemblfungi:YHL031C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005797"(Golgi medial cisterna)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0048193"(Golgi vesicle transport)|go:"GO:0048209"(regulation of vesicle targeting, to, from or within Golgi)|interpro:IPR023601|go:"GO:0006906"(vesicle fusion)|sgd:YHL031C(identity)	-	isoform-comment:No experimental confirmation available.	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:1VqWIwPpWs6WjW8eDoJUHz2pegw9606	rogid:pAzDzV46XXzIOB4p/oc1PlMc54E559292	intact-crc:03CB7B6C17F1E6B0|rigid:JPdB/sKMG5ILWTWJY5RggSkGkzw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38736	uniprotkb:Q8N6L0	intact:EBI-24365|uniprotkb:D3DKT7|ensemblfungi:YHL031C	intact:EBI-749265|uniprotkb:Q96MC3|ensembl:ENSP00000404220	psi-mi:gosr1_yeast(display_long)|uniprotkb:Golgi SNARE protein 1(gene name synonym)|uniprotkb:GOS1(gene name)|psi-mi:GOS1(display_short)|uniprotkb:Protein transport protein GOS1(gene name synonym)|uniprotkb:YHL031C(locus name)	psi-mi:kash5_human(display_long)|uniprotkb:KASH5(gene name)|psi-mi:KASH5(display_short)|uniprotkb:CCDC155(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 155(gene name synonym)|uniprotkb:KASH domain-containing protein 5(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11558519|imex:IM-24995-4738	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011832.1|sgd:S000001023|reactome:R-SCE-6811438|dip:DIP-2490N|reactome:R-SCE-6807878|ensemblfungi:YHL031C(gene)|ensemblfungi:YHL031C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005797"(Golgi medial cisterna)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0048193"(Golgi vesicle transport)|go:"GO:0048209"(regulation of vesicle targeting, to, from or within Golgi)|interpro:IPR023601|go:"GO:0006906"(vesicle fusion)|sgd:YHL031C(identity)	refseq:NP_653289.3|ensembl:ENSG00000161609(gene)|ensembl:ENST00000447857(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034397"(telomere localization)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051225"(spindle assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0090172"(microtubule cytoskeleton organization involved in homologous chromosome segregation)|go:"GO:0090220"(chromosome localization to nuclear envelope involved in homologous chromosome segregation)|go:"GO:0090619"(meiotic spindle pole)|interpro:IPR011992(EF-Hand type)|interpro:IPR028168|interpro:IPR028170|interpro:IPR039508|mint:Q8N6L0|rcsb pdb:6R2I|rcsb pdb:6WMF|entrezgene/locuslink:147872(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:pAzDzV46XXzIOB4p/oc1PlMc54E559292	rogid:Wl9L7AcvDHCZuKjYLn8QgGIbZTc9606	intact-crc:AFE4FD249C56846A|rigid:AwEJ1X9wku/5sYyHJ7+ja3HtWaQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38736	uniprotkb:Q12846	intact:EBI-24365|uniprotkb:D3DKT7|ensemblfungi:YHL031C	intact:EBI-744942|uniprotkb:Q15525|ensembl:ENSP00000317714|uniprotkb:Q6FHE8|uniprotkb:A8MXY0	psi-mi:gosr1_yeast(display_long)|uniprotkb:Golgi SNARE protein 1(gene name synonym)|uniprotkb:GOS1(gene name)|psi-mi:GOS1(display_short)|uniprotkb:Protein transport protein GOS1(gene name synonym)|uniprotkb:YHL031C(locus name)	psi-mi:stx4_human(display_long)|uniprotkb:Renal carcinoma antigen NY-REN-31(gene name synonym)|uniprotkb:STX4(gene name)|psi-mi:STX4(display_short)|uniprotkb:STX4A(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11558510|imex:IM-24995-4737	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011832.1|sgd:S000001023|reactome:R-SCE-6811438|dip:DIP-2490N|reactome:R-SCE-6807878|ensemblfungi:YHL031C(gene)|ensemblfungi:YHL031C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005797"(Golgi medial cisterna)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0048193"(Golgi vesicle transport)|go:"GO:0048209"(regulation of vesicle targeting, to, from or within Golgi)|interpro:IPR023601|go:"GO:0006906"(vesicle fusion)|sgd:YHL031C(identity)	ensembl:ENSG00000103496(gene)|refseq:NP_004595.2|ensembl:ENST00000313843(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0000322"(storage vacuole)|go:"GO:0002639"(positive regulation of immunoglobulin production)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005768"(endosome)|go:"GO:0005773"(vacuole)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006887"(exocytosis)|go:"GO:0006906"(vesicle fusion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016230"(sphingomyelin phosphodiesterase activator activity)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0032589"(neuron projection membrane)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035493"(SNARE complex assembly)|go:"GO:0035749"(myelin sheath adaxonal region)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0036477"(somatodendritic compartment)|go:"GO:0042581"(specific granule)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043197"(dendritic spine)|go:"GO:0043219"(lateral loop)|go:"GO:0043311"(positive regulation of eosinophil degranulation)|go:"GO:0045202"(synapse)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0048278"(vesicle docking)|go:"GO:0048284"(organelle fusion)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048787"(presynaptic active zone membrane)|go:"GO:0050921"(positive regulation of chemotaxis)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1902041"(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1903575"(cornified envelope assembly)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|reactome:R-HSA-114516|reactome:R-HSA-1236974|reactome:R-HSA-1445148|reactome:R-HSA-199992|reactome:R-HSA-449836|interpro:IPR006011(Syntaxin, N-terminal)|refseq:NP_001259025.1|entrezgene/locuslink:6810(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:pAzDzV46XXzIOB4p/oc1PlMc54E559292	rogid:NvOLGIGe/XO2aDPSpdPzrtKniZY9606	intact-crc:ADD662D3511F8BF0|rigid:szKyYXHC1lWBdl3DK2CWB+V8uW8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9H898-2	uniprotkb:P38732	intact:EBI-11529334|ensembl:ENSP00000319785	intact:EBI-24379|uniprotkb:D3DKT0|ensemblfungi:YHL039W	psi-mi:q9h898-2(display_long)|uniprotkb:ZMAT4(gene name)|psi-mi:ZMAT4(display_short)	psi-mi:efm1_yeast(display_long)|uniprotkb:EFM1(gene name)|psi-mi:EFM1(display_short)|uniprotkb:Elongation factor methyltransferase 1(gene name synonym)|uniprotkb:YHL039W(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11558501|imex:IM-24995-4736	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000165061(gene)|ensembl:ENST00000315769(transcript)|intact:EBI-2548542(isoform-parent)|uniprotkb:Q9H898-2(isoform-parent)|entrezgene/locuslink:79698(identity)	refseq:NP_011824.1|sgd:S000001031|dip:DIP-6582N|mint:P38732|ensemblfungi:YHL039W(gene)|ensemblfungi:YHL039W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0018026"(peptidyl-lysine monomethylation)|go:"GO:0018027"(peptidyl-lysine dimethylation)|interpro:IPR001214(SET)|interpro:IPR017119(Ribosomal lysine methyltransferase 1)|interpro:IPR044432|sgd:YHL039W(identity)	-	-	crc64:84BC2D3A204D9D29	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:LOS8TGoD/X97NtzSXSQ3uppdS6s9606	rogid:e5E4ijHZAIzzKWrxCzPqifR2v8U559292	intact-crc:CCC0B3202DB1C539|rigid:yR7MxZvdtOouBGQrd9CwGxb10Ro	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P10644	uniprotkb:P38756	intact:EBI-476431|uniprotkb:Q567S7|uniprotkb:K7ER48|ensembl:ENSP00000351410|ensembl:ENSP00000376475|ensembl:ENSP00000445625|ensembl:ENSP00000464977|ensembl:ENSP00000466459	intact:EBI-24431|uniprotkb:D3DKU6|ensemblfungi:YHR003C	psi-mi:kap0_human(display_long)|uniprotkb:Tissue-specific extinguisher 1(gene name synonym)|uniprotkb:PRKAR1A(gene name)|psi-mi:PRKAR1A(display_short)|uniprotkb:PKR1(gene name synonym)|uniprotkb:PRKAR1(gene name synonym)|uniprotkb:TSE1(gene name synonym)	psi-mi:tcd1_yeast(display_long)|uniprotkb:TCD1(gene name)|psi-mi:TCD1(display_short)|uniprotkb:"t(6)A37 dehydratase 1"(gene name synonym)|uniprotkb:YHR003C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11558584|imex:IM-24995-4745	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002725.1|refseq:NP_997636.1|refseq:NP_997637.1|refseq:XP_011523285.1|refseq:XP_011523286.1|refseq:XP_011523287.1|refseq:NP_001263218.1|refseq:NP_001263219.1|refseq:NP_001265362.1|dip:DIP-34368N|ensembl:ENSG00000108946(gene)|ensembl:ENST00000358598(transcript)|ensembl:ENST00000392711(transcript)|ensembl:ENST00000536854(transcript)|ensembl:ENST00000586397(transcript)|ensembl:ENST00000589228(transcript)|go:"GO:0001707"(mesoderm formation)|go:"GO:0004862"(cAMP-dependent protein kinase inhibitor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005771"(multivesicular body)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005952"(cAMP-dependent protein kinase complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007143"(female meiotic nuclear division)|go:"GO:0008603"(cAMP-dependent protein kinase regulator activity)|go:"GO:0010738"(regulation of protein kinase A signaling)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030552"(cAMP binding)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043949"(regulation of cAMP-mediated signaling)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045835"(negative regulation of meiotic nuclear division)|go:"GO:0046007"(negative regulation of activated T cell proliferation)|go:"GO:0060038"(cardiac muscle cell proliferation)|go:"GO:0097224"(sperm connecting piece)|go:"GO:0097546"(ciliary base)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:2000480"(negative regulation of cAMP-dependent protein kinase activity)|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR003117(cAMP-dependent protein kinase, regulatory subunit, type I/II alpha/beta)|interpro:IPR012198(cAMP-dependent protein kinase regulatory subunit)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR018488|rcsb pdb:5KJZ|reactome:R-HSA-163615|reactome:R-HSA-164378|reactome:R-HSA-180024|reactome:R-HSA-381676|reactome:R-HSA-432040|reactome:R-HSA-442720|reactome:R-HSA-5610787|reactome:R-HSA-9660821|reactome:R-HSA-9664323|reactome:R-HSA-983231|interpro:IPR018490|mint:P10644|rcsb pdb:5KJX|rcsb pdb:5KJY|entrezgene/locuslink:5573(identity)	refseq:NP_011866.1|sgd:S000001045|dip:DIP-4417N|mint:P38756|ensemblfungi:YHR003C(gene)|ensemblfungi:YHR003C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0008641"(ubiquitin-like modifier activating enzyme activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0061503"(tRNA threonylcarbamoyladenosine dehydratase)|go:"GO:0061504"(cyclic threonylcarbamoyladenosine biosynthetic process)|interpro:IPR000594(UBA/THIF-type NAD/FAD binding fold)|interpro:IPR035985|sgd:YHR003C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:dUZaCJQnC0KZEG4pccIqoT066VY9606	rogid:Mce7jBtBDJ9bSrw+cQDCbhK8DvY559292	intact-crc:78705D794B2608D5|rigid:OXtZ/T6SUL0umW5fFMkbi7YCawM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38744	uniprotkb:Q7L190	intact:EBI-13396|uniprotkb:D3DKR5|ensemblfungi:YHL018W	intact:EBI-710457|intact:EBI-28975079|ensembl:ENSP00000335306|uniprotkb:Q9H9N5|uniprotkb:Q9NVI6|uniprotkb:A8K4M7	psi-mi:phs_yeast(display_long)|uniprotkb:4-alpha-hydroxy-tetrahydropterin dehydratase(gene name synonym)|uniprotkb:Pterin carbinolamine dehydratase(gene name synonym)|uniprotkb:YHL018W(locus name)	psi-mi:dppa4_human(display_long)|uniprotkb:DPPA4(gene name)|psi-mi:DPPA4(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11558573|imex:IM-24995-4744	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011845.1|sgd:S000001010|interpro:IPR036428|interpro:IPR001533(Transcriptional coactivator/pterin dehydratase)|ensemblfungi:YHL018W(gene)|ensemblfungi:YHL018W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0008124"(4-alpha-hydroxytetrahydrobiopterin dehydratase activity)|dip:DIP-1872N|reactome:R-SCE-8964208|sgd:YHL018W(identity)	refseq:NP_060659.3|mint:Q7L190|reactome:R-HSA-2892247|ensembl:ENSG00000121570(gene)|ensembl:ENST00000335658(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0048731"(system development)|go:"GO:0060484"(lung-associated mesenchyme development)|interpro:IPR025891|interpro:IPR025892|interpro:IPR039590|interpro:IPR039836|ensembl:ENSP00000335306|entrezgene/locuslink:55211(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:7+JuLX1wFw/tkE4NcSCTK62b4DU559292	rogid:WKqQ0ipAAfKsDRuXJhtTWJcROdc9606	intact-crc:893C35D09FE05B08|rigid:v9KswGtAu+XifBD3ie3kecZgK+w	false	-	sufficient binding region:11-304	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q5JR59-3	uniprotkb:P38744	intact:EBI-11522433|ensembl:ENSP00000370186	intact:EBI-13396|uniprotkb:D3DKR5|ensemblfungi:YHL018W	psi-mi:q5jr59-3(display_long)|uniprotkb:MTUS2(gene name)|psi-mi:MTUS2(display_short)|uniprotkb:CAZIP(gene name synonym)|uniprotkb:Cardiac zipper protein(gene name synonym)|uniprotkb:KIAA0774(gene name synonym)|uniprotkb:Microtubule plus-end tracking protein TIP150(gene name synonym)|uniprotkb:TIP150(gene name synonym)	psi-mi:phs_yeast(display_long)|uniprotkb:4-alpha-hydroxy-tetrahydropterin dehydratase(gene name synonym)|uniprotkb:Pterin carbinolamine dehydratase(gene name synonym)|uniprotkb:YHL018W(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11558564|imex:IM-24995-4743	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000132938(gene)|ensembl:ENST00000380808(transcript)|intact:EBI-742948(isoform-parent)|uniprotkb:Q5JR59-3(isoform-parent)|entrezgene/locuslink:23281(identity)	refseq:NP_011845.1|sgd:S000001010|interpro:IPR036428|interpro:IPR001533(Transcriptional coactivator/pterin dehydratase)|ensemblfungi:YHL018W(gene)|ensemblfungi:YHL018W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0008124"(4-alpha-hydroxytetrahydrobiopterin dehydratase activity)|dip:DIP-1872N|reactome:R-SCE-8964208|sgd:YHL018W(identity)	-	isoform-comment:No experimental confirmation available.	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:npId9tC7VoLN/jteoBiRbSYChPs9606	rogid:7+JuLX1wFw/tkE4NcSCTK62b4DU559292	intact-crc:D400383C19E5DAE8|rigid:OqlY1umJIVGHXTYTVzd2M3kGP9k	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q02363	uniprotkb:P38744	intact:EBI-713450|ensembl:ENSP00000234091|ensembl:ENSP00000379585|ensembl:ENSP00000385465	intact:EBI-13396|uniprotkb:D3DKR5|ensemblfungi:YHL018W	psi-mi:id2_human(display_long)|uniprotkb:Inhibitor of DNA binding 2(gene name synonym)|uniprotkb:ID2(gene name)|psi-mi:ID2(display_short)|uniprotkb:BHLHB26(gene name synonym)|uniprotkb:Class B basic helix-loop-helix protein 26(gene name synonym)|uniprotkb:Inhibitor of differentiation 2(gene name synonym)	psi-mi:phs_yeast(display_long)|uniprotkb:4-alpha-hydroxy-tetrahydropterin dehydratase(gene name synonym)|uniprotkb:Pterin carbinolamine dehydratase(gene name synonym)|uniprotkb:YHL018W(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11558555|imex:IM-24995-4742	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000115738(gene)|ensembl:ENST00000234091(transcript)|ensembl:ENST00000331129(transcript)|ensembl:ENST00000396290(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000791"(euchromatin)|go:"GO:0003166"(bundle of His development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007507"(heart development)|go:"GO:0007623"(circadian rhythm)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0030154"(cell differentiation)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033598"(mammary gland epithelial cell proliferation)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0043353"(enucleate erythrocyte differentiation)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0045578"(negative regulation of B cell differentiation)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045651"(positive regulation of macrophage differentiation)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0045777"(positive regulation of blood pressure)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0048663"(neuron fate commitment)|go:"GO:0048711"(positive regulation of astrocyte differentiation)|go:"GO:0051148"(negative regulation of muscle cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0061030"(epithelial cell differentiation involved in mammary gland alveolus development)|go:"GO:0061031"(endodermal digestive tract morphogenesis)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0071931"(positive regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0090398"(cellular senescence)|go:"GO:0140416"(transcription regulator inhibitor activity)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000177"(regulation of neural precursor cell proliferation)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR026052|interpro:IPR036638|mint:Q02363|rcsb pdb:4AYA|reactome:R-HSA-9031628|refseq:NP_002157.2|dip:DIP-46874N|entrezgene/locuslink:3398(identity)	refseq:NP_011845.1|sgd:S000001010|interpro:IPR036428|interpro:IPR001533(Transcriptional coactivator/pterin dehydratase)|ensemblfungi:YHL018W(gene)|ensemblfungi:YHL018W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0008124"(4-alpha-hydroxytetrahydrobiopterin dehydratase activity)|dip:DIP-1872N|reactome:R-SCE-8964208|sgd:YHL018W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:zKX4mIq64fyS8DVPGQNeL7+c50w9606	rogid:7+JuLX1wFw/tkE4NcSCTK62b4DU559292	intact-crc:17955673507DA3C0|rigid:oNdc+G4sFcPRPhFkvBSc240INoY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96BA8	uniprotkb:P38775	intact:EBI-6942903|ensembl:ENSP00000481956|intact:MINT-268046|intact:MINT-8162577|uniprotkb:Q8N2D5|uniprotkb:Q96CP0	intact:EBI-24520|uniprotkb:D3DKZ3|ensemblfungi:YHR045W	psi-mi:cr3l1_human(display_long)|uniprotkb:CREB3L1(gene name)|psi-mi:CREB3L1(display_short)|uniprotkb:OASIS(gene name synonym)|uniprotkb:PSEC0238(orf name)|uniprotkb:Old astrocyte specifically-induced substance(gene name synonym)	psi-mi:yhk5_yeast(display_long)|uniprotkb:YHR045W(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11558631|imex:IM-24995-4750	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157613(gene)|ensembl:ENST00000621158(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0070278"(extracellular matrix constituent secretion)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029805|mint:Q96BA8|reactome:R-HSA-8874211|refseq:NP_443086.1|entrezgene/locuslink:90993(identity)	sgd:S000001087|refseq:NP_011911.1|dip:DIP-5587N|mint:P38775|ensemblfungi:YHR045W(gene)|ensemblfungi:YHR045W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0016021"(integral component of membrane)|sgd:YHR045W(identity)	-	comment:mint|function:"Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE"	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:sMWUFmBeBBCO+T0Y2CuB/un1lBg9606	rogid:DIfjsK4iO1b4tmBBj9gsbfGBAoE559292	intact-crc:3DA41666D300435B|rigid:AlqmBVYU0BvJlGUq9nEYs5yqXZI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UJW9	uniprotkb:P38770	intact:EBI-748621|uniprotkb:Q96CQ2|uniprotkb:B3KQB3|ensembl:ENSP00000325414|ensembl:ENSP00000375882	intact:EBI-24507|uniprotkb:D3DKY3|ensemblfungi:YHR036W	psi-mi:srtd3_human(display_long)|uniprotkb:Replication protein-binding trans-activator(gene name synonym)|uniprotkb:SERTAD3(gene name)|psi-mi:SERTAD3(display_short)|uniprotkb:RBT1(gene name synonym)	psi-mi:brl1_yeast(display_long)|uniprotkb:BRL1(gene name)|psi-mi:BRL1(display_short)|uniprotkb:BRR6-like protein 1(gene name synonym)|uniprotkb:YHR036W(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11558622|imex:IM-24995-4749	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006723242.1|refseq:NP_037500.2|refseq:NP_976219.1|refseq:XP_005258889.1|ensembl:ENSG00000167565(gene)|ensembl:ENST00000322354(transcript)|ensembl:ENST00000392028(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR009263(SERTA)|interpro:IPR039585|entrezgene/locuslink:29946(identity)	refseq:NP_011901.1|sgd:S000001078|dip:DIP-5580N|mint:P38770|ensemblfungi:YHR036W(gene)|ensemblfungi:YHR036W_mRNA(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006998"(nuclear envelope organization)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0051028"(mRNA transport)|go:"GO:0055088"(lipid homeostasis)|interpro:IPR018767|interpro:IPR040202|sgd:YHR036W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:zraVKcqHA7SNRrMV50iyPK6O7ok9606	rogid:gLJXF3VREvr8+oW8HZYTfHDho4A559292	intact-crc:BAB2F59F39ABA8E6|rigid:PAl3pboTff33jepoEJ8ViVlEyUk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9BXL8	uniprotkb:P38770	intact:EBI-1773949|uniprotkb:Q8TB18|uniprotkb:Q9NWK7|ensembl:ENSP00000337226|ensembl:ENSP00000376369	intact:EBI-24507|uniprotkb:D3DKY3|ensemblfungi:YHR036W	psi-mi:cdca4_human(display_long)|uniprotkb:CDCA4(gene name)|psi-mi:CDCA4(display_short)|uniprotkb:HEPP(gene name synonym)|uniprotkb:Hematopoietic progenitor protein(gene name synonym)	psi-mi:brl1_yeast(display_long)|uniprotkb:BRL1(gene name)|psi-mi:BRL1(display_short)|uniprotkb:BRR6-like protein 1(gene name synonym)|uniprotkb:YHR036W(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11558613|imex:IM-24995-4748	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060425.2|refseq:NP_663747.1|ensembl:ENSG00000170779(gene)|ensembl:ENST00000336219(transcript)|ensembl:ENST00000392590(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0048096"|interpro:IPR009263(SERTA)|mint:Q9BXL8|entrezgene/locuslink:55038(identity)	refseq:NP_011901.1|sgd:S000001078|dip:DIP-5580N|mint:P38770|ensemblfungi:YHR036W(gene)|ensemblfungi:YHR036W_mRNA(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006998"(nuclear envelope organization)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0051028"(mRNA transport)|go:"GO:0055088"(lipid homeostasis)|interpro:IPR018767|interpro:IPR040202|sgd:YHR036W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:sxwZ0Yw0uG+MjnhKtVv+8PHvPCo9606	rogid:gLJXF3VREvr8+oW8HZYTfHDho4A559292	intact-crc:676F3AB2768880A9|rigid:X/OgNRGYdVkcb3UluzUCgcjpNdI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38769	uniprotkb:P63010-2	intact:EBI-24503|uniprotkb:D3DKY2|ensemblfungi:YHR035W	intact:EBI-11529439|ensembl:ENSP00000482835|ensembl:ENSP00000483185	psi-mi:nel1_yeast(display_long)|uniprotkb:NEL1(gene name)|psi-mi:NEL1(display_short)|uniprotkb:Non-ERES-localized SEC23 homolog 1(gene name synonym)|uniprotkb:YHR035W(locus name)	psi-mi:p63010-2(display_long)|uniprotkb:ADTB2(gene name synonym)|uniprotkb:AP105B(gene name synonym)|uniprotkb:Adaptor protein complex AP-2 subunit beta(gene name synonym)|uniprotkb:Adaptor-related protein complex 2 subunit beta(gene name synonym)|uniprotkb:Beta-2-adaptin(gene name synonym)|uniprotkb:Beta-adaptin(gene name synonym)|uniprotkb:CLAPB1(gene name synonym)|uniprotkb:Clathrin assembly protein complex 2 beta large chain(gene name synonym)|uniprotkb:AP2B1(gene name)|psi-mi:AP2B1(display_short)|uniprotkb:Plasma membrane adaptor HA2/AP2 adaptin beta subunit(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11558604|imex:IM-24995-4747	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011900.1|sgd:S000001077|dip:DIP-806N|mint:P38769|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:0090110"(COPII-coated vesicle cargo loading)|interpro:IPR006896(Sec23/Sec24 trunk region)|interpro:IPR036174|interpro:IPR036180|interpro:IPR036465|interpro:IPR037364|ensemblfungi:YHR035W_mRNA(transcript)|ensemblfungi:YHR035W(gene)|sgd:YHR035W(identity)	intact:EBI-432924(isoform-parent)|uniprotkb:P63010-2(isoform-parent)|ensembl:ENSG00000006125(gene)|ensembl:ENST00000610402(transcript)|ensembl:ENST00000618940(transcript)|entrezgene/locuslink:163(identity)	-	crc64:C42D24351D4FA75D	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:qiEwgSjz+4y1ObyBwCewGx9/NPc559292	rogid:RpFHKbLgdxGqagTUoCCgQ2W+9nw9606	intact-crc:030163FF722E1CB0|rigid:VzAs8w+jsKqLm4oY1Hmkgr7Iy8o	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8IYF3-3	uniprotkb:P38763	intact:EBI-11523345|ensembl:ENSP00000363453	intact:EBI-24475|uniprotkb:D3DKW8|ensemblfungi:YHR022C	psi-mi:q8iyf3-3(display_long)|uniprotkb:TEX11(gene name)|psi-mi:TEX11(display_short)|uniprotkb:Protein ZIP4 homolog(gene name synonym)|uniprotkb:ZIP4(gene name synonym)	psi-mi:yhi2_yeast(display_long)|uniprotkb:YHR022C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11558593|imex:IM-24995-4746	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000120498(gene)|ensembl:ENST00000374333(transcript)|intact:EBI-742397(isoform-parent)|uniprotkb:Q8IYF3-3(isoform-parent)|entrezgene/locuslink:56159(identity)	refseq:NP_011887.1|sgd:S000001064|dip:DIP-1876N|ensemblfungi:YHR022C(gene)|ensemblfungi:YHR022C_mRNA(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0012505"(endomembrane system)|interpro:IPR001806(Ras GTPase)|interpro:IPR027417|reactome:R-SCE-6811440|reactome:R-SCE-8873719|reactome:R-SCE-8876198|sgd:YHR022C(identity)	-	-	crc64:8A4A500681EF3D74	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:PUAMFmnm5ZV2rnJ1rhm9ZeRCixg9606	rogid:jcjAXgGlLpgsG473/s41ALnbUQo559292	intact-crc:F533C1D6239B0D84|rigid:8zgdx4i3Cj+n7krc8HseIoEhcHc	false	sufficient binding region:9-925	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38781	uniprotkb:Q9Y6N9-4	intact:EBI-24549|uniprotkb:D3DL05|ensemblfungi:YHR056C	intact:EBI-11523636|ensembl:ENSP00000436934	psi-mi:rsc30_yeast(display_long)|uniprotkb:RSC30(gene name)|psi-mi:RSC30(display_short)|uniprotkb:Remodel the structure of chromatin complex subunit 30(gene name synonym)|uniprotkb:YHR056C(locus name)	psi-mi:q9y6n9-4(display_long)|uniprotkb:USH1C(gene name)|psi-mi:USH1C(display_short)|uniprotkb:AIE75(gene name synonym)|uniprotkb:Antigen NY-CO-38/NY-CO-37(gene name synonym)|uniprotkb:Autoimmune enteropathy-related antigen AIE-75(gene name synonym)|uniprotkb:Protein PDZ-73(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-3(gene name synonym)|uniprotkb:Usher syndrome type-1C protein(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11558651|imex:IM-24995-4752	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011923.2|sgd:S000001098|dip:DIP-4275N|ensemblfungi:YHR056C(gene)|ensemblfungi:YHR056C_mRNA(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006337"(nucleosome disassembly)|rcsb pdb:6KW4|rcsb pdb:6KW5|rcsb pdb:6V8O|rcsb pdb:6V92|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016586"(RSC-type complex)|interpro:IPR001138(Fungal transcriptional regulatory protein, N-terminal)|interpro:IPR036864|rcsb pdb:6K15|rcsb pdb:6KW3|sgd:YHR056C(identity)	ensembl:ENSG00000006611(gene)|ensembl:ENST00000527020(transcript)|intact:EBI-954308(isoform-parent)|uniprotkb:Q9Y6N9-4(isoform-parent)|entrezgene/locuslink:10083(identity)	-	-	isoform-comment:No experimental confirmation available.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:NzGOxIaNyDat2EcQdWPobugunh0559292	rogid:lC4fbXfsFOZFtutcdQYHSWpgcJY9606	intact-crc:E51F37FC77551BB4|rigid:NGbrqKUhac/AX2xIvvMSab9r7RA	false	sufficient binding region:52-883	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96KN7-4	uniprotkb:P38781	intact:EBI-11525164|ensembl:ENSP00000372391	intact:EBI-24549|uniprotkb:D3DL05|ensemblfungi:YHR056C	psi-mi:q96kn7-4(display_long)|uniprotkb:RPGRIP1(gene name)|psi-mi:RPGRIP1(display_short)	psi-mi:rsc30_yeast(display_long)|uniprotkb:RSC30(gene name)|psi-mi:RSC30(display_short)|uniprotkb:Remodel the structure of chromatin complex subunit 30(gene name synonym)|uniprotkb:YHR056C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11558640|imex:IM-24995-4751	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-1050213(isoform-parent)|ensembl:ENSG00000092200(gene)|ensembl:ENST00000382933(transcript)|uniprotkb:Q96KN7-4(isoform-parent)|entrezgene/locuslink:57096(identity)	refseq:NP_011923.2|sgd:S000001098|dip:DIP-4275N|ensemblfungi:YHR056C(gene)|ensemblfungi:YHR056C_mRNA(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006337"(nucleosome disassembly)|rcsb pdb:6KW4|rcsb pdb:6KW5|rcsb pdb:6V8O|rcsb pdb:6V92|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016586"(RSC-type complex)|interpro:IPR001138(Fungal transcriptional regulatory protein, N-terminal)|interpro:IPR036864|rcsb pdb:6K15|rcsb pdb:6KW3|sgd:YHR056C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Xy0433uM/nWhWLM/EsfESPJDIy49606	rogid:NzGOxIaNyDat2EcQdWPobugunh0559292	intact-crc:AB0D612EBE98F1FE|rigid:+lhorYUPJWwM4GE9f+q87nqe1Iw	false	-	sufficient binding region:52-883	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38815	uniprotkb:Q8WW34-2	intact:EBI-24665|uniprotkb:D3DL55|ensemblfungi:YHR105W	intact:EBI-11528917|ensembl:ENSP00000369959	psi-mi:ypt35_yeast(display_long)|uniprotkb:YHR105W(locus name)|uniprotkb:YPT35(gene name)|psi-mi:YPT35(display_short)	psi-mi:q8ww34-2(display_long)|uniprotkb:TMEM239(gene name)|psi-mi:TMEM239(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11558700|imex:IM-24995-4757	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011973.1|sgd:S000001147|dip:DIP-1881N|ensemblfungi:YHR105W(gene)|ensemblfungi:YHR105W_mRNA(transcript)|go:"GO:0005768"(endosome)|go:"GO:0010008"(endosome membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|interpro:IPR001683(Phox-like)|interpro:IPR036871|interpro:IPR037917|sgd:YHR105W(identity)	intact:EBI-9675724(isoform-parent)|uniprotkb:Q8WW34-2(isoform-parent)|ensembl:ENSG00000198326(gene)|ensembl:ENST00000380585(transcript)|entrezgene/locuslink:100288797(identity)	-	crc64:2ADD21AF107094DC	isoform-comment:No experimental confirmation available.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:fUTJG8BaTveH3zB/0W1vNh4BU2Y559292	rogid:1VqWIwPpWs6WjW8eDoJUHz2pegw9606	intact-crc:A9CC051045DFACF5|rigid:Tc5Z00Ijf1H/4/CoUQ9k/8XVdxs	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q6RW13-2	uniprotkb:P38815	intact:EBI-11522760|ensembl:ENSP00000365816	intact:EBI-24665|uniprotkb:D3DL55|ensemblfungi:YHR105W	psi-mi:q6rw13-2(display_long)|uniprotkb:AGTRAP(gene name)|psi-mi:AGTRAP(display_short)|uniprotkb:AT1 receptor-associated protein(gene name synonym)|uniprotkb:ATRAP(gene name synonym)	psi-mi:ypt35_yeast(display_long)|uniprotkb:YHR105W(locus name)|uniprotkb:YPT35(gene name)|psi-mi:YPT35(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11558691|imex:IM-24995-4756	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000177674(gene)|ensembl:ENST00000376629(transcript)|intact:EBI-741181(isoform-parent)|uniprotkb:Q6RW13-2(isoform-parent)|entrezgene/locuslink:57085(identity)	refseq:NP_011973.1|sgd:S000001147|dip:DIP-1881N|ensemblfungi:YHR105W(gene)|ensemblfungi:YHR105W_mRNA(transcript)|go:"GO:0005768"(endosome)|go:"GO:0010008"(endosome membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|interpro:IPR001683(Phox-like)|interpro:IPR036871|interpro:IPR037917|sgd:YHR105W(identity)	-	-	crc64:2ADD21AF107094DC	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:PNzVis/8puQZBJ562gCqZKc078s9606	rogid:fUTJG8BaTveH3zB/0W1vNh4BU2Y559292	intact-crc:ADE50A364A7E7DB7|rigid:TljLFTagZAaBJcwIVz4e6tNIXTU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38815	uniprotkb:Q13137	intact:EBI-24665|uniprotkb:D3DL55|ensemblfungi:YHR105W	intact:EBI-739580|uniprotkb:B4DDC4|uniprotkb:E7ENK0|uniprotkb:Q53FQ5|uniprotkb:Q53HB5|uniprotkb:Q6IBN9|uniprotkb:Q9BTF7|uniprotkb:B2RBT0|ensembl:ENSP00000258947|uniprotkb:B4E0C0|uniprotkb:E7ETP5|uniprotkb:B4DDT4|uniprotkb:B4DP36|uniprotkb:E9PBE5	psi-mi:ypt35_yeast(display_long)|uniprotkb:YHR105W(locus name)|uniprotkb:YPT35(gene name)|psi-mi:YPT35(display_short)	psi-mi:caco2_human(display_long)|uniprotkb:CALCOCO2(gene name)|psi-mi:CALCOCO2(display_short)|uniprotkb:NDP52(gene name synonym)|uniprotkb:Nuclear domain 10 protein NDP52(gene name synonym)|uniprotkb:Antigen nuclear dot 52 kDa protein(gene name synonym)|uniprotkb:Nuclear dot protein 52(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11558682|imex:IM-24995-4755	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011973.1|sgd:S000001147|dip:DIP-1881N|ensemblfungi:YHR105W(gene)|ensemblfungi:YHR105W_mRNA(transcript)|go:"GO:0005768"(endosome)|go:"GO:0010008"(endosome membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|interpro:IPR001683(Phox-like)|interpro:IPR036871|interpro:IPR037917|sgd:YHR105W(identity)	refseq:NP_001248319.1|refseq:NP_001248320.1|refseq:NP_001248322.1|refseq:NP_005822.1|ensembl:ENSG00000136436(gene)|ensembl:ENST00000258947(transcript)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016032"(viral process)|go:"GO:0016605"(PML body)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0098792"(xenophagy)|go:"GO:1901098"(positive regulation of autophagosome maturation)|interpro:IPR041611|interpro:IPR041641|mint:Q13137|rcsb pdb:2MXP|rcsb pdb:3VVV|rcsb pdb:3VVW|rcsb pdb:4GXL|rcsb pdb:4HAN|rcsb pdb:4XKL|rcsb pdb:5AAQ|rcsb pdb:5Z7A|rcsb pdb:5Z7L|refseq:NP_001248324.1|dip:DIP-57534N|entrezgene/locuslink:10241(identity)	-	crc64:2ADD21AF107094DC	crc64:609B121DA1A9DCB8	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:fUTJG8BaTveH3zB/0W1vNh4BU2Y559292	rogid:N/GPJUGBK+Dh5Cg+csmafphuo9M9606	intact-crc:CD991E367596DB71|rigid:uCIg90GaLpsIGsMeB/4WqatfkPQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8TAP6	uniprotkb:P38792	intact:EBI-742887|ensembl:ENSP00000262127|uniprotkb:Q658N5|uniprotkb:Q9H9U7|uniprotkb:B0YJB2|uniprotkb:B4DXG5|uniprotkb:B4DZW1	intact:EBI-1757|uniprotkb:D3DL18|ensemblfungi:YHR069C	psi-mi:cep76_human(display_long)|uniprotkb:CEP76(gene name)|psi-mi:CEP76(display_short)|uniprotkb:C18orf9(gene name synonym)	psi-mi:rrp4_yeast(display_long)|uniprotkb:RRP4(gene name)|psi-mi:RRP4(display_short)|uniprotkb:Ribosomal RNA-processing protein 4(gene name synonym)|uniprotkb:YHR069C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11558673|imex:IM-24995-4754	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_079175.2|ensembl:ENSG00000101624(gene)|ensembl:ENST00000262127(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0046599"(regulation of centriole replication)|interpro:IPR028926|interpro:IPR038765|mint:Q8TAP6|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_001258918.1|entrezgene/locuslink:79959(identity)	refseq:NP_011936.1|sgd:S000001111|dip:DIP-5888N|mint:P38792|ensemblfungi:YHR069C(gene)|ensemblfungi:YHR069C_mRNA(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0071034"(CUT catabolic process)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071049"|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR004088(K Homology, type 1)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR025721|interpro:IPR026699|interpro:IPR036612|rcsb pdb:4IFD|rcsb pdb:4OO1|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5G06|rcsb pdb:5JEA|rcsb pdb:5K36|rcsb pdb:5OKZ|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-429958|reactome:R-SCE-450385|reactome:R-SCE-450513|reactome:R-SCE-6791226|sgd:YHR069C(identity)	-	-	crc64:0718A7ABF42E9B9B	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:fWzb8oIU35oVWomyDrf8u5sbxUk9606	rogid:ZgBS9xjR7jC96sAb0m63ElPvM7M559292	intact-crc:6DE46728ED142151|rigid:FdK9E/hOr2p/p0E8zMPp69HfxXg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38792	uniprotkb:G5E962	intact:EBI-1757|uniprotkb:D3DL18|ensemblfungi:YHR069C	intact:EBI-11525615|ensembl:ENSP00000328177	psi-mi:rrp4_yeast(display_long)|uniprotkb:RRP4(gene name)|psi-mi:RRP4(display_short)|uniprotkb:Ribosomal RNA-processing protein 4(gene name synonym)|uniprotkb:YHR069C(locus name)	psi-mi:g5e962_human(display_long)|uniprotkb:hCG_1644200(orf name)|uniprotkb:MAGEA11(gene name)|psi-mi:MAGEA11(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11558662|imex:IM-24995-4753	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011936.1|sgd:S000001111|dip:DIP-5888N|mint:P38792|ensemblfungi:YHR069C(gene)|ensemblfungi:YHR069C_mRNA(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0071034"(CUT catabolic process)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071049"|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR004088(K Homology, type 1)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR025721|interpro:IPR026699|interpro:IPR036612|rcsb pdb:4IFD|rcsb pdb:4OO1|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5G06|rcsb pdb:5JEA|rcsb pdb:5K36|rcsb pdb:5OKZ|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-429958|reactome:R-SCE-450385|reactome:R-SCE-450513|reactome:R-SCE-6791226|sgd:YHR069C(identity)	refseq:NP_001011544.1|ensembl:ENSG00000185247(gene)|ensembl:ENST00000333104(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016604"(nuclear body)|interpro:IPR002190(MAGE protein)|interpro:IPR021072|interpro:IPR030099|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|entrezgene/locuslink:4110(identity)	-	crc64:0718A7ABF42E9B9B	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:ZgBS9xjR7jC96sAb0m63ElPvM7M559292	rogid:sVB0aA6yibWUx/d2SE+pwpKKgtI9606	intact-crc:ACC4099BF5937301|rigid:IDlrQJoGydTypSzPj8mX6Azug1k	false	-	sufficient binding region:82-400	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8N6L0	uniprotkb:P38837	intact:EBI-749265|uniprotkb:Q96MC3|ensembl:ENSP00000404220	intact:EBI-24733|uniprotkb:D3DL82|uniprotkb:Q6Q5G1|ensemblfungi:YHR133C	psi-mi:kash5_human(display_long)|uniprotkb:KASH5(gene name)|psi-mi:KASH5(display_short)|uniprotkb:CCDC155(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 155(gene name synonym)|uniprotkb:KASH domain-containing protein 5(gene name synonym)	psi-mi:nsg1_yeast(display_long)|uniprotkb:INSIG homolog 1(gene name synonym)|uniprotkb:YHR133C(locus name)|uniprotkb:NSG1(gene name)|psi-mi:NSG1(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11558745|imex:IM-24995-4762	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_653289.3|ensembl:ENSG00000161609(gene)|ensembl:ENST00000447857(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034397"(telomere localization)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051225"(spindle assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0090172"(microtubule cytoskeleton organization involved in homologous chromosome segregation)|go:"GO:0090220"(chromosome localization to nuclear envelope involved in homologous chromosome segregation)|go:"GO:0090619"(meiotic spindle pole)|interpro:IPR011992(EF-Hand type)|interpro:IPR028168|interpro:IPR028170|interpro:IPR039508|mint:Q8N6L0|rcsb pdb:6R2I|rcsb pdb:6WMF|entrezgene/locuslink:147872(identity)	sgd:S000001175|refseq:NP_012001.1|dip:DIP-2775N|mint:P38837|ensemblfungi:YHR133C(gene)|ensemblfungi:YHR133C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016126"(sterol biosynthetic process)|go:"GO:0034399"(nuclear periphery)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR025929|sgd:YHR133C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Wl9L7AcvDHCZuKjYLn8QgGIbZTc9606	rogid:ALle5Ub0gjK3Uh+6sfIgbfa7BYw559292	intact-crc:F5E637C37298CA42|rigid:GGHvrnEzAxYlA3jNZxR9DvvfxHw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8TAP6	uniprotkb:P38828	intact:EBI-742887|ensembl:ENSP00000262127|uniprotkb:Q658N5|uniprotkb:Q9H9U7|uniprotkb:B0YJB2|uniprotkb:B4DXG5|uniprotkb:B4DZW1	intact:EBI-24700|uniprotkb:D3DL71|ensemblfungi:YHR121W	psi-mi:cep76_human(display_long)|uniprotkb:CEP76(gene name)|psi-mi:CEP76(display_short)|uniprotkb:C18orf9(gene name synonym)	psi-mi:lsm12_yeast(display_long)|uniprotkb:YHR121W(locus name)|uniprotkb:LSM12(gene name)|psi-mi:LSM12(display_short)|uniprotkb:Sm-like protein 12(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11558736|imex:IM-24995-4761	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_079175.2|ensembl:ENSG00000101624(gene)|ensembl:ENST00000262127(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0046599"(regulation of centriole replication)|interpro:IPR028926|interpro:IPR038765|mint:Q8TAP6|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_001258918.1|entrezgene/locuslink:79959(identity)	refseq:NP_011989.1|sgd:S000001163|dip:DIP-5545N|mint:P38828|ensemblfungi:YHR121W(gene)|ensemblfungi:YHR121W_mRNA(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016070"(RNA metabolic process)|interpro:IPR016521(Uncharacterised conserved protein UCP007783, YHR121w)|interpro:IPR019181|interpro:IPR039683|sgd:YHR121W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:fWzb8oIU35oVWomyDrf8u5sbxUk9606	rogid:6xw9WGjtFwkmKlO6QHoSSS2aMro559292	intact-crc:1CE177B47D0A54B6|rigid:4MdpdXBICplRwkaqS7/1NVvtVeQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96GY0	uniprotkb:P38822	intact:EBI-5458880|uniprotkb:Q9Y372|ensembl:ENSP00000263849	intact:EBI-3889|uniprotkb:E9P8V2|uniprotkb:D3DL64|ensemblfungi:YHR114W	psi-mi:zc21a_human(display_long)|uniprotkb:ZC2HC1A(gene name)|psi-mi:ZC2HC1A(display_short)|uniprotkb:C8orf70(gene name synonym)|uniprotkb:FAM164A(gene name synonym)|uniprotkb:CGI-62(orf name)	psi-mi:bzz1_yeast(display_long)|uniprotkb:BZZ1(gene name)|psi-mi:BZZ1(display_short)|uniprotkb:LAS17-binding protein 7(gene name synonym)|uniprotkb:LSB7(gene name synonym)|uniprotkb:YHR114W(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11558727|imex:IM-24995-4760	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_057094.2|ensembl:ENSG00000104427(gene)|ensembl:ENST00000263849(transcript)|go:"GO:0046872"(metal ion binding)|interpro:IPR026319|entrezgene/locuslink:51101(identity)	refseq:NP_011982.1|sgd:S000001156|dip:DIP-2143N|mint:P38822|ensemblfungi:YHR114W(gene)|ensemblfungi:YHR114W_mRNA(transcript)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006897"(endocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0009651"(response to salt stress)|go:"GO:0030479"(actin cortical patch)|go:"GO:0043332"(mating projection tip)|go:"GO:0045010"(actin nucleation)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR027267|interpro:IPR031160|interpro:IPR036028|rcsb pdb:1ZUU|rcsb pdb:2A28|reactome:R-SCE-8856828|reactome:R-SCE-9013406|reactome:R-SCE-9696270|sgd:YHR114W(identity)	-	-	crc64:5C73DACC69611B41	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:5QYEwHhPJBrdqbU1jKnxdZFYC7c9606	rogid:lnoTdZ+pWCE2mDz3Ha7VQOOCfM8559292	intact-crc:6D3FE2FD9705218B|rigid:c7PMZXUdiAE6cIMTeiRiWPtID/c	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UI14	uniprotkb:P38815	intact:EBI-712367|ensembl:ENSP00000222008|uniprotkb:Q7Z4Y2|uniprotkb:Q9Y3R1	intact:EBI-24665|uniprotkb:D3DL55|ensemblfungi:YHR105W	psi-mi:praf1_human(display_long)|uniprotkb:PRA1 family protein 1(gene name synonym)|uniprotkb:RABAC1(gene name)|psi-mi:RABAC1(display_short)|uniprotkb:PRA1(gene name synonym)|uniprotkb:PRAF1(gene name synonym)	psi-mi:ypt35_yeast(display_long)|uniprotkb:YHR105W(locus name)|uniprotkb:YPT35(gene name)|psi-mi:YPT35(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11558718|imex:IM-24995-4759	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006414.2|ensembl:ENSG00000105404(gene)|ensembl:ENST00000222008(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0070064"(proline-rich region binding)|interpro:IPR004895(Prenylated rab acceptor PRA1)|mint:Q9UI14|entrezgene/locuslink:10567(identity)	refseq:NP_011973.1|sgd:S000001147|dip:DIP-1881N|ensemblfungi:YHR105W(gene)|ensemblfungi:YHR105W_mRNA(transcript)|go:"GO:0005768"(endosome)|go:"GO:0010008"(endosome membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|interpro:IPR001683(Phox-like)|interpro:IPR036871|interpro:IPR037917|sgd:YHR105W(identity)	-	-	crc64:2ADD21AF107094DC	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:WS2rUY7yXRbR7pqWgfUCbnEiDbg9606	rogid:fUTJG8BaTveH3zB/0W1vNh4BU2Y559292	intact-crc:8834FF625BA636B8|rigid:prvpKhWrJiDUl4kjr1YUwrA7ZTc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96HR9	uniprotkb:P38815	intact:EBI-750345|uniprotkb:Q96LM0|uniprotkb:B2RE01|uniprotkb:A0A1L5BXV3|uniprotkb:D6W5Z0|ensembl:ENSP00000378861	intact:EBI-24665|uniprotkb:D3DL55|ensemblfungi:YHR105W	psi-mi:reep6_human(display_long)|uniprotkb:Polyposis locus protein 1-like 1(gene name synonym)|uniprotkb:REEP6(gene name)|psi-mi:REEP6(display_short)|uniprotkb:C19orf32(gene name synonym)|uniprotkb:DP1L1(gene name synonym)	psi-mi:ypt35_yeast(display_long)|uniprotkb:YHR105W(locus name)|uniprotkb:YPT35(gene name)|psi-mi:YPT35(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11558709|imex:IM-24995-4758	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_612402.1|refseq:NP_001316485.1|ensembl:ENSG00000115255(gene)|ensembl:ENST00000395479(transcript)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030665"(clathrin-coated vesicle membrane)|go:"GO:0032386"(regulation of intracellular transport)|go:"GO:0050908"(detection of light stimulus involved in visual perception)|interpro:IPR004345(TB2/DP1 and HVA22 related protein)|mint:Q96HR9|reactome:R-HSA-381753|go:"GO:0005634"(nucleus)|entrezgene/locuslink:92840(identity)	refseq:NP_011973.1|sgd:S000001147|dip:DIP-1881N|ensemblfungi:YHR105W(gene)|ensemblfungi:YHR105W_mRNA(transcript)|go:"GO:0005768"(endosome)|go:"GO:0010008"(endosome membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|interpro:IPR001683(Phox-like)|interpro:IPR036871|interpro:IPR037917|sgd:YHR105W(identity)	-	-	crc64:2ADD21AF107094DC	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2017/05/05	rogid:pB8AjjNTpmaaLJ8j7MCBM45UAHE9606	rogid:fUTJG8BaTveH3zB/0W1vNh4BU2Y559292	intact-crc:BB7338533807EA7A|rigid:c9CbZDzhbB3Kso14dHqlrn66Jag	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q13049	uniprotkb:P38868	intact:EBI-742790|ensembl:ENSP00000363095|ensembl:ENSP00000408292|uniprotkb:Q9NQP8	intact:EBI-24840|uniprotkb:A0A1S0T004|ensemblfungi:YHR180W	psi-mi:tri32_human(display_long)|uniprotkb:Zinc finger protein HT2A(gene name synonym)|uniprotkb:72 kDa Tat-interacting protein(gene name synonym)|uniprotkb:TRIM32(gene name)|psi-mi:TRIM32(display_short)|uniprotkb:HT2A(gene name synonym)|uniprotkb:Tripartite motif-containing protein 32(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM32(gene name synonym)	psi-mi:yhy0_yeast(display_long)|uniprotkb:YHR180W(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11558791|imex:IM-24995-4767	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0043621"(protein self-association)|go:"GO:0045087"(innate immune response)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051155"(positive regulation of striated muscle cell differentiation)|go:"GO:0061564"(axon development)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1902187"|go:"GO:1902230"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:1903265"(positive regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:1903883"(positive regulation of interleukin-17-mediated signaling pathway)|go:"GO:1903886"("positive regulation of chemokine (C-C motif) ligand 20 production")|go:"GO:2000147"(positive regulation of cell motility)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENSG00000119401(gene)|ensembl:ENST00000373983(transcript)|ensembl:ENST00000450136(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001894"(tissue homeostasis)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005863"(striated muscle myosin thick filament)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007014"(actin ubiquitination)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009411"(response to UV)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0017022"(myosin binding)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030957"(Tat protein binding)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034612"(response to tumor necrosis factor)|go:"GO:0042802"(identical protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|interpro:IPR000315(Zinc finger, B-box)|refseq:NP_001093149.1|refseq:XP_011516700.1|refseq:NP_036342.2|refseq:XP_005251870.1|interpro:IPR001258(NHL repeat)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR013017(NHL repeat, subgroup)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR027370|mint:Q13049|rcsb pdb:2CT2|rcsb pdb:5FEY|reactome:R-HSA-3134975|reactome:R-HSA-983168|refseq:XP_016869975.1|entrezgene/locuslink:22954(identity)	sgd:S000001223|dip:DIP-4332N|ensemblfungi:YHR180W(gene)|ensemblfungi:YHR180W_mRNA(transcript)|go:"GO:0016021"(integral component of membrane)|sgd:YHR180W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:XuqprQd10kSpsuyGs+FSdzIdJ/Y9606	rogid:E7zJN1iVyb08WvBGa7NXcqw4sqw559292	intact-crc:D7E05ADCDAE721FC|rigid:AjIWCkstYp9m6gL/ZjCq5bWK7gc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38868	uniprotkb:O43765	intact:EBI-24840|uniprotkb:A0A1S0T004|ensemblfungi:YHR180W	intact:EBI-347996|ensembl:ENSP00000221566|ensembl:ENSP00000503397|ensembl:ENSP00000504495|uniprotkb:Q9BTZ9|intact:EBI-1045243|uniprotkb:Q6FIA9|uniprotkb:D6W610	psi-mi:yhy0_yeast(display_long)|uniprotkb:YHR180W(locus name)	psi-mi:sgta_human(display_long)|uniprotkb:SGTA(gene name)|psi-mi:SGTA(display_short)|uniprotkb:SGT(gene name synonym)|uniprotkb:Alpha-SGT(gene name synonym)|uniprotkb:Vpu-binding protein(gene name synonym)|uniprotkb:SGT1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11558782|imex:IM-24995-4766	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000001223|dip:DIP-4332N|ensemblfungi:YHR180W(gene)|ensemblfungi:YHR180W_mRNA(transcript)|go:"GO:0016021"(integral component of membrane)|sgd:YHR180W(identity)	rcsb pdb:4CPG|rcsb pdb:4GOD|rcsb pdb:4GOE|rcsb pdb:4GOF|reactome:R-HSA-9609523|rcsb pdb:2VYI|ensembl:ENSG00000104969(gene)|ensembl:ENST00000221566(transcript)|ensembl:ENST00000676943(transcript)|ensembl:ENST00000677149(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072380"(TRC complex)|go:"GO:0098850"(extrinsic component of synaptic vesicle membrane)|go:"GO:1903070"(negative regulation of ER-associated ubiquitin-dependent protein catabolic process)|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)|go:"GO:1903646"(positive regulation of chaperone-mediated protein folding)|go:"GO:1904288"(BAT3 complex binding)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR032374|mint:O43765|refseq:XP_011526480.1|refseq:NP_003012.1|entrezgene/locuslink:6449(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:E7zJN1iVyb08WvBGa7NXcqw4sqw559292	rogid:r/Cyj4UJk/cS8QdrbjhTZMPCigI9606	intact-crc:44BCBE8AE9FCF101|rigid:xhGW+dGqWWFn41O+2W907wqnGZk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96BA8	uniprotkb:P38842	intact:EBI-6942903|ensembl:ENSP00000481956|intact:MINT-268046|intact:MINT-8162577|uniprotkb:Q8N2D5|uniprotkb:Q96CP0	intact:EBI-24752|uniprotkb:D3DL89|uniprotkb:Q6B2K3|ensemblfungi:YHR140W	psi-mi:cr3l1_human(display_long)|uniprotkb:CREB3L1(gene name)|psi-mi:CREB3L1(display_short)|uniprotkb:OASIS(gene name synonym)|uniprotkb:PSEC0238(orf name)|uniprotkb:Old astrocyte specifically-induced substance(gene name synonym)	psi-mi:yhu0_yeast(display_long)|uniprotkb:YHR140W(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11558772|imex:IM-24995-4765	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157613(gene)|ensembl:ENST00000621158(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0070278"(extracellular matrix constituent secretion)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029805|mint:Q96BA8|reactome:R-HSA-8874211|refseq:NP_443086.1|entrezgene/locuslink:90993(identity)	refseq:NP_012009.1|sgd:S000001182|dip:DIP-1786N|ensemblfungi:YHR140W(gene)|ensemblfungi:YHR140W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR006838(FAR-17a/AIG1-like protein)|sgd:YHR140W(identity)	-	comment:mint|function:"Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE"	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:sMWUFmBeBBCO+T0Y2CuB/un1lBg9606	rogid:3CroWy45MlZdD8WyMGvawdwQhrs559292	intact-crc:2E503ECABE461942|rigid:0DA9kqjAyPL7wELZ/7YsnW6pIKk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8N6L0	uniprotkb:P38842	intact:EBI-749265|uniprotkb:Q96MC3|ensembl:ENSP00000404220	intact:EBI-24752|uniprotkb:D3DL89|uniprotkb:Q6B2K3|ensemblfungi:YHR140W	psi-mi:kash5_human(display_long)|uniprotkb:KASH5(gene name)|psi-mi:KASH5(display_short)|uniprotkb:CCDC155(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 155(gene name synonym)|uniprotkb:KASH domain-containing protein 5(gene name synonym)	psi-mi:yhu0_yeast(display_long)|uniprotkb:YHR140W(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11558763|imex:IM-24995-4764	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_653289.3|ensembl:ENSG00000161609(gene)|ensembl:ENST00000447857(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034397"(telomere localization)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051225"(spindle assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0090172"(microtubule cytoskeleton organization involved in homologous chromosome segregation)|go:"GO:0090220"(chromosome localization to nuclear envelope involved in homologous chromosome segregation)|go:"GO:0090619"(meiotic spindle pole)|interpro:IPR011992(EF-Hand type)|interpro:IPR028168|interpro:IPR028170|interpro:IPR039508|mint:Q8N6L0|rcsb pdb:6R2I|rcsb pdb:6WMF|entrezgene/locuslink:147872(identity)	refseq:NP_012009.1|sgd:S000001182|dip:DIP-1786N|ensemblfungi:YHR140W(gene)|ensemblfungi:YHR140W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR006838(FAR-17a/AIG1-like protein)|sgd:YHR140W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Wl9L7AcvDHCZuKjYLn8QgGIbZTc9606	rogid:3CroWy45MlZdD8WyMGvawdwQhrs559292	intact-crc:B13ECB3D6FFC0071|rigid:pFlcWSa+b6rZZSlavQm3DHY7grw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P63279	uniprotkb:P38838	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	intact:EBI-24737|uniprotkb:D3DL83|ensemblfungi:YHR134W	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:wss1_yeast(display_long)|uniprotkb:YHR134W(locus name)|uniprotkb:WSS1(gene name)|psi-mi:WSS1(display_short)|uniprotkb:Weak suppressor of SMT3 protein 1(gene name synonym)|uniprotkb:DNA damage response protein WSS1(gene name synonym)|uniprotkb:SUMO-dependent isopeptidase WSS1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11558754|imex:IM-24995-4763	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N|entrezgene/locuslink:7329(identity)	refseq:NP_012002.1|sgd:S000001176|dip:DIP-1600N|ensemblfungi:YHR134W(gene)|ensemblfungi:YHR134W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0006508"(proteolysis)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0010224"(response to UV-B)|go:"GO:0010225"(response to UV-C)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019985"(translesion synthesis)|go:"GO:0032183"(SUMO binding)|go:"GO:0036205"(histone catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0061665"(SUMO ligase activity)|go:"GO:0106300"(protein-DNA covalent cross-linking repair)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|go:"GO:1990466"(protein autosumoylation)|interpro:IPR013536(WLM)|sgd:YHR134W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	rogid:nRxYgrZjnBdPN8uneoPl3Rq01+g559292	intact-crc:9F82AB2B85A73533|rigid:mRIfEHJp/M50+xqUmA9KVh7Eb1c	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38871	uniprotkb:G5E962	intact:EBI-24852|uniprotkb:D3DLD2|ensemblfungi:YHR184W	intact:EBI-11525615|ensembl:ENSP00000328177	psi-mi:ssp1_yeast(display_long)|uniprotkb:SSP1(gene name)|psi-mi:SSP1(display_short)|uniprotkb:YHR184W(locus name)	psi-mi:g5e962_human(display_long)|uniprotkb:hCG_1644200(orf name)|uniprotkb:MAGEA11(gene name)|psi-mi:MAGEA11(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11558820|imex:IM-24995-4770	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000001227|refseq:NP_012054.1|dip:DIP-1674N|ensemblfungi:YHR184W(gene)|ensemblfungi:YHR184W_mRNA(transcript)|go:"GO:0005628"(prospore membrane)|go:"GO:0030476"(ascospore wall assembly)|go:"GO:0032120"(ascospore-type prospore membrane formation)|go:"GO:0051301"(cell division)|go:"GO:0070056"(prospore membrane leading edge)|sgd:YHR184W(identity)	refseq:NP_001011544.1|ensembl:ENSG00000185247(gene)|ensembl:ENST00000333104(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016604"(nuclear body)|interpro:IPR002190(MAGE protein)|interpro:IPR021072|interpro:IPR030099|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|entrezgene/locuslink:4110(identity)	-	crc64:A199EB4159771A03	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:oYmvoKYf2OWiVyfG4zRm731HTRs559292	rogid:sVB0aA6yibWUx/d2SE+pwpKKgtI9606	intact-crc:860B3AEF57E24250|rigid:V13Cy51tf7GR/hmN/udbtu+VqSk	false	-	sufficient binding region:82-400	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38868	uniprotkb:Q9UMX0	intact:EBI-24840|uniprotkb:A0A1S0T004|ensemblfungi:YHR180W	intact:EBI-741480|uniprotkb:Q8IXS9|uniprotkb:Q8N2Q3|uniprotkb:Q9H0T8|uniprotkb:Q9H3R4|uniprotkb:Q9HAZ5|intact:EBI-28967608|ensembl:ENSP00000365576|uniprotkb:Q5T6J5|uniprotkb:Q5T6J9|uniprotkb:A0A024R284	psi-mi:yhy0_yeast(display_long)|uniprotkb:YHR180W(locus name)	psi-mi:ubql1_human(display_long)|uniprotkb:Protein linking IAP with cytoskeleton 1(gene name synonym)|uniprotkb:UBQLN1(gene name)|psi-mi:UBQLN1(display_short)|uniprotkb:DA41(gene name synonym)|uniprotkb:PLIC1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11558811|imex:IM-24995-4769	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000001223|dip:DIP-4332N|ensemblfungi:YHR180W(gene)|ensemblfungi:YHR180W_mRNA(transcript)|go:"GO:0016021"(integral component of membrane)|sgd:YHR180W(identity)	ensembl:ENST00000257468|ensembl:ENSP00000257468|ensembl:ENSP00000365576|ensembl:ENSG00000135018(gene)|ensembl:ENST00000376395(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000502"(proteasome complex)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016235"(aggresome)|go:"GO:0016236"(macroautophagy)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0019900"(kinase binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035973"(aggrephagy)|go:"GO:0042802"(identical protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0097352"(autophagosome maturation)|go:"GO:1901340"(negative regulation of store-operated calcium channel activity)|go:"GO:1902175"(regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)|interpro:IPR000626(Ubiquitin)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR028430|interpro:IPR029071|mint:Q9UMX0|rcsb pdb:2JY5|rcsb pdb:2JY6|rcsb pdb:2KLC|reactome:R-HSA-8856825|refseq:NP_038466.2|refseq:NP_444295.1|dip:DIP-41629N|entrezgene/locuslink:29979(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:E7zJN1iVyb08WvBGa7NXcqw4sqw559292	rogid:nCFfZbGCTvRYaXhQ4R99XblslvM9606	intact-crc:8BCFCA3FF22AD3C5|rigid:q50hN7Nm+coUXkalINXCfafkEsE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38868	uniprotkb:Q6P1W5	intact:EBI-24840|uniprotkb:A0A1S0T004|ensemblfungi:YHR180W	intact:EBI-946029|uniprotkb:B3KVT1|uniprotkb:Q96IC8|ensembl:ENSP00000435634|uniprotkb:D3DPR3|uniprotkb:E9PJ76	psi-mi:yhy0_yeast(display_long)|uniprotkb:YHR180W(locus name)	psi-mi:ca094_human(display_long)|uniprotkb:C1orf94(gene name)|psi-mi:C1orf94(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11558800|imex:IM-24995-4768	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000001223|dip:DIP-4332N|ensemblfungi:YHR180W(gene)|ensemblfungi:YHR180W_mRNA(transcript)|go:"GO:0016021"(integral component of membrane)|sgd:YHR180W(identity)	refseq:NP_001128206.1|refseq:NP_116273.2|ensembl:ENSG00000142698(gene)|ensembl:ENST00000488417(transcript)|interpro:IPR031496|entrezgene/locuslink:84970(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:E7zJN1iVyb08WvBGa7NXcqw4sqw559292	rogid:y1o4xWvTl2CBA1J7jsP7y8ZjLzM9606	intact-crc:0D428B886F60BE25|rigid:hVpdiBz4Xv9ToxTQ5x2xu/Sj0QU	false	-	sufficient binding region:191-598	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UMX0	uniprotkb:P38886	intact:EBI-741480|uniprotkb:Q8IXS9|uniprotkb:Q8N2Q3|uniprotkb:Q9H0T8|uniprotkb:Q9H3R4|uniprotkb:Q9HAZ5|intact:EBI-28967608|ensembl:ENSP00000365576|uniprotkb:Q5T6J5|uniprotkb:Q5T6J9|uniprotkb:A0A024R284	intact:EBI-15949|ensemblfungi:YHR200W|uniprotkb:D3DLE9	psi-mi:ubql1_human(display_long)|uniprotkb:Protein linking IAP with cytoskeleton 1(gene name synonym)|uniprotkb:UBQLN1(gene name)|psi-mi:UBQLN1(display_short)|uniprotkb:DA41(gene name synonym)|uniprotkb:PLIC1(gene name synonym)	psi-mi:rpn10_yeast(display_long)|uniprotkb:RPN10(gene name)|psi-mi:RPN10(display_short)|uniprotkb:MCB1(gene name synonym)|uniprotkb:SUN1(gene name synonym)|uniprotkb:YHR200W(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11558859|imex:IM-24995-4774	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000257468|ensembl:ENSP00000257468|ensembl:ENSP00000365576|ensembl:ENSG00000135018(gene)|ensembl:ENST00000376395(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000502"(proteasome complex)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016235"(aggresome)|go:"GO:0016236"(macroautophagy)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0019900"(kinase binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035973"(aggrephagy)|go:"GO:0042802"(identical protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0097352"(autophagosome maturation)|go:"GO:1901340"(negative regulation of store-operated calcium channel activity)|go:"GO:1902175"(regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)|interpro:IPR000626(Ubiquitin)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR028430|interpro:IPR029071|mint:Q9UMX0|rcsb pdb:2JY5|rcsb pdb:2JY6|rcsb pdb:2KLC|reactome:R-HSA-8856825|refseq:NP_038466.2|refseq:NP_444295.1|dip:DIP-41629N|entrezgene/locuslink:29979(identity)	ensemblfungi:YHR200W(gene)|ensemblfungi:YHR200W_mRNA(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|sgd:S000001243|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0036435"(K48-linked polyubiquitin modification-dependent protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043248"(proteasome assembly)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR027040|interpro:IPR036465|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5LN1|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5MPD|rcsb pdb:5MPE|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|refseq:NP_012070.3|dip:DIP-2100N|mint:P38886|sgd:YHR200W(identity)	-	-	crc64:8A05198B0CD7C0C3	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:nCFfZbGCTvRYaXhQ4R99XblslvM9606	rogid:Lg2bjPWMUcvXdLDZZMWFWyXbCcA559292	intact-crc:D826C147E19FB85D|rigid:jRQ6SH8wVZdoEyLJO0cGcrIO2eI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9BYV6-2	uniprotkb:P38886	intact:EBI-11522718|ensembl:ENSP00000297348	intact:EBI-15949|ensemblfungi:YHR200W|uniprotkb:D3DLE9	psi-mi:q9byv6-2(display_long)|uniprotkb:TRIM55(gene name)|psi-mi:TRIM55(display_short)|uniprotkb:MURF2(gene name synonym)|uniprotkb:Muscle-specific RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 29(gene name synonym)|uniprotkb:RNF29(gene name synonym)|uniprotkb:p50(isoform synonym)	psi-mi:rpn10_yeast(display_long)|uniprotkb:RPN10(gene name)|psi-mi:RPN10(display_short)|uniprotkb:MCB1(gene name synonym)|uniprotkb:SUN1(gene name synonym)|uniprotkb:YHR200W(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11558850|imex:IM-24995-4773	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-2341179(isoform-parent)|uniprotkb:Q9BYV6-2(isoform-parent)|ensembl:ENSG00000147573(gene)|ensembl:ENST00000353317(transcript)|entrezgene/locuslink:84675(identity)	ensemblfungi:YHR200W(gene)|ensemblfungi:YHR200W_mRNA(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|sgd:S000001243|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0036435"(K48-linked polyubiquitin modification-dependent protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043248"(proteasome assembly)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR027040|interpro:IPR036465|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5LN1|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5MPD|rcsb pdb:5MPE|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|refseq:NP_012070.3|dip:DIP-2100N|mint:P38886|sgd:YHR200W(identity)	-	-	crc64:8A05198B0CD7C0C3	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:9t8UhK+Z1yBqjnQrOqPD76NuXGg9606	rogid:Lg2bjPWMUcvXdLDZZMWFWyXbCcA559292	intact-crc:F1F34B78878EFA32|rigid:YoDMoSc/LsIPVqeFajJU5v39FdY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9HCM9-2	uniprotkb:P38879	intact:EBI-11523450|ensembl:ENSP00000365847|ensembl:ENSP00000373095|ensembl:ENSP00000373097|ensembl:ENSP00000379797|ensembl:ENSP00000379800|ensembl:ENSP00000383486|ensembl:ENSP00000387445|ensembl:ENSP00000389198|ensembl:ENSP00000389852|ensembl:ENSP00000392130|ensembl:ENSP00000394353|ensembl:ENSP00000396986|ensembl:ENSP00000398956|ensembl:ENSP00000401071|ensembl:ENSP00000401184|ensembl:ENSP00000404340|ensembl:ENSP00000404904|ensembl:ENSP00000411582|ensembl:ENSP00000412743|ensembl:ENSP00000414525|ensembl:ENSP00000415259	intact:EBI-6379|uniprotkb:D3DLE1|ensemblfungi:YHR193C	psi-mi:q9hcm9-2(display_long)|uniprotkb:TRIM39(gene name)|psi-mi:TRIM39(display_short)|uniprotkb:RING finger protein 23(gene name synonym)|uniprotkb:RNF23(gene name synonym)|uniprotkb:TFP(gene name synonym)|uniprotkb:Testis-abundant finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 39(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM39(gene name synonym)|uniprotkb:TIM39beta(isoform synonym)	psi-mi:naca_yeast(display_long)|uniprotkb:EGD2(gene name)|psi-mi:EGD2(display_short)|uniprotkb:Alpha-NAC(gene name synonym)|uniprotkb:GAL4 DNA-binding enhancer protein 2(gene name synonym)|uniprotkb:YHR193C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11558840|imex:IM-24995-4772	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-739510(isoform-parent)|ensembl:ENSG00000204599(gene)|ensembl:ENSG00000206495(gene)|ensembl:ENSG00000224994(gene)|ensembl:ENSG00000226437(gene)|ensembl:ENSG00000229929(gene)|ensembl:ENSG00000230308(gene)|ensembl:ENSG00000232839(gene)|ensembl:ENST00000376659(transcript)|ensembl:ENST00000383601(transcript)|ensembl:ENST00000383603(transcript)|ensembl:ENST00000396548(transcript)|ensembl:ENST00000396551(transcript)|ensembl:ENST00000400644(transcript)|ensembl:ENST00000414015(transcript)|ensembl:ENST00000419790(transcript)|ensembl:ENST00000430502(transcript)|ensembl:ENST00000431272(transcript)|ensembl:ENST00000433900(transcript)|ensembl:ENST00000438076(transcript)|ensembl:ENST00000438859(transcript)|ensembl:ENST00000440117(transcript)|ensembl:ENST00000443109(transcript)|ensembl:ENST00000446397(transcript)|ensembl:ENST00000449318(transcript)|ensembl:ENST00000450778(transcript)|ensembl:ENST00000451132(transcript)|ensembl:ENST00000452705(transcript)|ensembl:ENST00000458607(transcript)|uniprotkb:Q9HCM9-2(isoform-parent)|entrezgene/locuslink:56658(identity)	sgd:S000001236|refseq:NP_012063.3|mint:P38879|dip:DIP-2098N|ensemblfungi:YHR193C(gene)|ensemblfungi:YHR193C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005854"(nascent polypeptide-associated complex)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0070300"(phosphatidic acid binding)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|interpro:IPR002715(Nascent polypeptide-associated complex NAC)|interpro:IPR009060(UBA-like)|interpro:IPR016641(Nascent polypeptide-associated complex, alpha subunit)|interpro:IPR038187|interpro:IPR044034|sgd:YHR193C(identity)	-	-	crc64:86CE0C4E6194C286	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:UfSn2+IVRxtGomVeDGdZpL7mz5I9606	rogid:IjsgR+hZDgTQDvy2Wf8JEX4kF+A559292	intact-crc:5F0DDD9D1ACE9E94|rigid:A0MHhunKyob6sVK1SSl8etIg/pU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38879	uniprotkb:P20290-2	intact:EBI-6379|uniprotkb:D3DLE1|ensemblfungi:YHR193C	intact:EBI-1054703|ensembl:ENSP00000338516	psi-mi:naca_yeast(display_long)|uniprotkb:EGD2(gene name)|psi-mi:EGD2(display_short)|uniprotkb:Alpha-NAC(gene name synonym)|uniprotkb:GAL4 DNA-binding enhancer protein 2(gene name synonym)|uniprotkb:YHR193C(locus name)	psi-mi:p20290-2(display_long)|uniprotkb:BTF3b(isoform synonym)|uniprotkb:BTF3(gene name)|psi-mi:BTF3(display_short)|uniprotkb:NACB(gene name synonym)|uniprotkb:RNA polymerase B transcription factor 3(gene name synonym)|uniprotkb:OK/SW-cl.8(orf name)|uniprotkb:Nascent polypeptide-associated complex subunit beta(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11558831|imex:IM-24995-4771	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000001236|refseq:NP_012063.3|mint:P38879|dip:DIP-2098N|ensemblfungi:YHR193C(gene)|ensemblfungi:YHR193C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005854"(nascent polypeptide-associated complex)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0070300"(phosphatidic acid binding)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|interpro:IPR002715(Nascent polypeptide-associated complex NAC)|interpro:IPR009060(UBA-like)|interpro:IPR016641(Nascent polypeptide-associated complex, alpha subunit)|interpro:IPR038187|interpro:IPR044034|sgd:YHR193C(identity)	intact:EBI-1054687(btf3_human)|ensembl:ENSG00000145741(gene)|ensembl:ENST00000335895(transcript)|uniprotkb:P20290-2(isoform-parent)|entrezgene/locuslink:689(identity)	-	crc64:86CE0C4E6194C286	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:IjsgR+hZDgTQDvy2Wf8JEX4kF+A559292	rogid:nViZ1CRkho2stQQ1ts0kUzwhOO09606	intact-crc:654ABA8E270A87B2|rigid:YbdnKjy0+72+LWtuT2IYSXhsw1o	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38932	uniprotkb:Q13190	intact:EBI-20444|uniprotkb:D6VU50|ensemblfungi:YGL095C	intact:EBI-714206|uniprotkb:Q5U0D4|uniprotkb:Q7Z3T6|uniprotkb:Q9BUG1|uniprotkb:B2R8T2|ensembl:ENSP00000294179|uniprotkb:F8W8Q9	psi-mi:vps45_yeast(display_long)|uniprotkb:VPS45(gene name)|psi-mi:VPS45(display_short)|uniprotkb:STT10(gene name synonym)|uniprotkb:VPL28(gene name synonym)|uniprotkb:YGL095C(locus name)	psi-mi:stx5_human(display_long)|uniprotkb:STX5(gene name)|psi-mi:STX5(display_short)|uniprotkb:STX5A(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11558896|imex:IM-24995-4778	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003063|refseq:NP_011420.3|ensemblfungi:YGL095C(gene)|ensemblfungi:YGL095C_mRNA(transcript)|go:"GO:0000011"(vacuole inheritance)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0007033"(vacuole organization)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0035543"(positive regulation of SNARE complex assembly)|go:"GO:0048210"(Golgi vesicle fusion to target membrane)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR001619(Sec1-like protein)|interpro:IPR027482|interpro:IPR036045|interpro:IPR043127|interpro:IPR043154|reactome:R-SCE-983231|dip:DIP-2693N|mint:P38932|sgd:YGL095C(identity)	refseq:NP_003155.2|ensembl:ENSG00000162236(gene)|ensembl:ENST00000294179(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006906"(vesicle fusion)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0031982"(vesicle)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034498"(early endosome to Golgi transport)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0045296"(cadherin binding)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048278"(vesicle docking)|go:"GO:0048280"(vesicle fusion with Golgi apparatus)|go:"GO:0090166"(Golgi disassembly)|go:"GO:1903358"(regulation of Golgi organization)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|interpro:IPR021538|mint:Q13190|rcsb pdb:3EFO|reactome:R-HSA-204005|reactome:R-HSA-5694530|reactome:R-HSA-6807878|reactome:R-HSA-6811438|reactome:R-HSA-8980692|reactome:R-HSA-9013106|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|reactome:R-HSA-9013408|reactome:R-HSA-9609523|refseq:NP_001231595.1|refseq:NP_001317223.1|dip:DIP-56987N|entrezgene/locuslink:6811(identity)	-	crc64:4AA50D568228228F	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:HSNdSBz2AD5AS/nSUjPV02ym8HQ559292	rogid:cR4cS695ZWQQ5Bkim9HqmCE0hCE9606	intact-crc:F2BD2AE5C89C6CBF|rigid:fn3RpZMtWU2aSdpMHGtsEOjS0pI	false	-	sufficient binding region:55-355	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96HU1	uniprotkb:P38913	intact:EBI-7362971|uniprotkb:B0QY79|intact:UNK-5498582|uniprotkb:Q7Z709|uniprotkb:Q9NT69|ensembl:ENSP00000248929	intact:EBI-6763|ensemblfungi:YDL045C|uniprotkb:D6VRV1	psi-mi:sgsm3_human(display_long)|uniprotkb:SGSM3(gene name)|psi-mi:SGSM3(display_short)|uniprotkb:MAP(gene name synonym)|uniprotkb:RABGAPLP(gene name synonym)|uniprotkb:RUTBC3(gene name synonym)|uniprotkb:RUN and TBC1 domain-containing protein 3(gene name synonym)|uniprotkb:Rab-GTPase-activating protein-like protein(gene name synonym)|uniprotkb:Merlin-associated protein(gene name synonym)	psi-mi:fad1_yeast(display_long)|uniprotkb:FAD1(gene name)|psi-mi:FAD1(display_short)|uniprotkb:FMN adenylyltransferase(gene name synonym)|uniprotkb:D2702(orf name)|uniprotkb:YDL045C(locus name)|uniprotkb:FAD pyrophosphorylase(gene name synonym)|uniprotkb:Flavin adenine dinucleotide synthase(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11558887|imex:IM-24995-4777	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001288778.1|refseq:NP_056520.2|ensembl:ENSG00000100359(gene)|ensembl:ENST00000248929(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005829"(cytosol)|go:"GO:0005921"(gap junction)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007049"(cell cycle)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032483"(regulation of Rab protein signal transduction)|go:"GO:0032486"(Rap protein signal transduction)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0048227"(plasma membrane to endosome transport)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR001452(Src homology-3)|interpro:IPR004012(RUN)|interpro:IPR035833|interpro:IPR035969|interpro:IPR036028|interpro:IPR037213|entrezgene/locuslink:27352(identity)	refseq:NP_010239.1|sgd:S000002203|ensemblfungi:YDL045C(gene)|ensemblfungi:YDL045C_mRNA(transcript)|go:"GO:0003919"(FMN adenylyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006747"(FAD biosynthetic process)|interpro:IPR002500(Phosphoadenosine phosphosulphate reductase)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|rcsb pdb:2WSI|reactome:R-SCE-196843|dip:DIP-4735N|sgd:YDL045C(identity)	-	function:May play a cooperative role in NF2-mediated growth suppression of cells|comment:mint|comment:homomint	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:9V+BpqGXordWG7hcdP/l6QL4+Lg9606	rogid:fdv5ldkxx7ZxwNTBS+oAAbwPkOc559292	intact-crc:96B46C9B810EA869|rigid:MBbbXEOtPz5tgr0lhq0U/cqNHgA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96BA8	uniprotkb:P38894	intact:EBI-6942903|ensembl:ENSP00000481956|intact:MINT-268046|intact:MINT-8162577|uniprotkb:Q8N2D5|uniprotkb:Q96CP0	intact:EBI-6990|uniprotkb:D3DLG0|ensemblfungi:YHR211W	psi-mi:cr3l1_human(display_long)|uniprotkb:CREB3L1(gene name)|psi-mi:CREB3L1(display_short)|uniprotkb:OASIS(gene name synonym)|uniprotkb:PSEC0238(orf name)|uniprotkb:Old astrocyte specifically-induced substance(gene name synonym)	psi-mi:flo5_yeast(display_long)|uniprotkb:YHR211W(locus name)|uniprotkb:FLO5(gene name)|psi-mi:FLO5(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11558877|imex:IM-24995-4776	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157613(gene)|ensembl:ENST00000621158(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0070278"(extracellular matrix constituent secretion)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029805|mint:Q96BA8|reactome:R-HSA-8874211|refseq:NP_443086.1|entrezgene/locuslink:90993(identity)	refseq:NP_012081.1|sgd:S000001254|dip:DIP-4056N|ensemblfungi:YHR211W(gene)|ensemblfungi:YHR211W_mRNA(transcript)|go:"GO:0000128"(flocculation)|go:"GO:0005537"(mannose binding)|go:"GO:0005576"(extracellular region)|go:"GO:0009277"(fungal-type cell wall)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0031589"(cell-substrate adhesion)|go:"GO:0071944"(cell periphery)|interpro:IPR001389(Flocculin)|interpro:IPR011658(PA14)|interpro:IPR025928|interpro:IPR037524|rcsb pdb:2XJP|rcsb pdb:2XJQ|rcsb pdb:2XJR|rcsb pdb:2XJS|rcsb pdb:2XJT|rcsb pdb:2XJU|rcsb pdb:2XJV|rcsb pdb:4AHW|rcsb pdb:4AHX|rcsb pdb:4AHY|rcsb pdb:4AHZ|rcsb pdb:4AI0|rcsb pdb:4AI1|rcsb pdb:4AI2|rcsb pdb:4AI3|sgd:YHR211W(identity)	-	comment:mint|function:"Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE"	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:sMWUFmBeBBCO+T0Y2CuB/un1lBg9606	rogid:kWs25Mzne+np7M/ebYwa4Fg1yqg559292	intact-crc:5BBE14385CD605A5|rigid:6ICkyyI0yZYCyTwytnUg3TaeUrA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O14641	uniprotkb:P38891	intact:EBI-740850|ensembl:ENSP00000005340|uniprotkb:Q53XM0|uniprotkb:D3DTN3	intact:EBI-3455|uniprotkb:D3DLF7|ensemblfungi:YHR208W	psi-mi:dvl2_human(display_long)|uniprotkb:DSH homolog 2(gene name synonym)|uniprotkb:DVL2(gene name)|psi-mi:DVL2(display_short)	psi-mi:bca1_yeast(display_long)|uniprotkb:Protein TWT1(gene name synonym)|uniprotkb:Protein ECA39(gene name synonym)|uniprotkb:BAT1(gene name)|psi-mi:BAT1(display_short)|uniprotkb:ECA39(gene name synonym)|uniprotkb:TWT1(gene name synonym)|uniprotkb:YHR208W(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11558868|imex:IM-24995-4775	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004413.1|ensembl:ENSG00000004975(gene)|ensembl:ENST00000005340(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005109"(frizzled binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0007507"(heart development)|go:"GO:0016235"(aggresome)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044340"(canonical Wnt signaling pathway involved in regulation of cell proliferation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0150012"(positive regulation of neuron projection arborization)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008341(Dishevelled-2 region)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:O14641|rcsb pdb:2REY|rcsb pdb:3CBX|rcsb pdb:3CBY|rcsb pdb:3CBZ|rcsb pdb:3CC0|rcsb pdb:4WIP|rcsb pdb:5LNP|rcsb pdb:5SUY|rcsb pdb:5SUZ|rcsb pdb:6IW3|rcsb pdb:6JCK|reactome:R-HSA-201681|reactome:R-HSA-201688|reactome:R-HSA-2028269|reactome:R-HSA-4086400|reactome:R-HSA-4608870|reactome:R-HSA-4641258|reactome:R-HSA-4641262|reactome:R-HSA-5099900|reactome:R-HSA-5368598|reactome:R-HSA-5663220|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9673324|ensembl:ENSP00000005340|dip:DIP-34433N|entrezgene/locuslink:1856(identity)	sgd:S000001251|reactome:R-SCE-70895|refseq:NP_012078.3|dip:DIP-6475N|ensemblfungi:YHR208W(gene)|ensemblfungi:YHR208W_mRNA(transcript)|go:"GO:0004084"(branched-chain-amino-acid transaminase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0009082"(branched-chain amino acid biosynthetic process)|go:"GO:0009083"(branched-chain amino acid catabolic process)|go:"GO:0009097"(isoleucine biosynthetic process)|go:"GO:0009098"(leucine biosynthetic process)|go:"GO:0009099"(valine biosynthetic process)|go:"GO:0019509"(L-methionine salvage from methylthioadenosine)|go:"GO:0050048"("L-leucine:2-oxoglutarate aminotransferase activity")|go:"GO:0052654"(L-leucine transaminase activity)|go:"GO:0052655"(L-valine transaminase activity)|go:"GO:0052656"(L-isoleucine transaminase activity)|interpro:IPR001544(Aminotransferase, class IV)|interpro:IPR005786(Branched-chain amino acid aminotransferase II)|interpro:IPR018300|interpro:IPR033939|interpro:IPR036038|interpro:IPR043131|interpro:IPR043132|sgd:YHR208W(identity)	-	-	crc64:E76604F326A7C674	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:2Vdc8oRnT4Mz/j+EXQXrL3AszOc9606	rogid:Rz/okB+egLztOJhwPzzPpl8yXlc559292	intact-crc:25624E1CFF42A62D|rigid:afXbXqSons1qGvi/zoOlKg8qE0s	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P39009	uniprotkb:O14641	intact:EBI-6194|uniprotkb:D6VRP9|ensemblfungi:YDL101C	intact:EBI-740850|ensembl:ENSP00000005340|uniprotkb:Q53XM0|uniprotkb:D3DTN3	psi-mi:dun1_yeast(display_long)|uniprotkb:DUN1(gene name)|psi-mi:DUN1(display_short)|uniprotkb:D2370(orf name)|uniprotkb:YDL101C(locus name)	psi-mi:dvl2_human(display_long)|uniprotkb:DSH homolog 2(gene name synonym)|uniprotkb:DVL2(gene name)|psi-mi:DVL2(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11558943|imex:IM-24995-4783	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010182.1|sgd:S000002259|dip:DIP-1772N|reactome:R-SCE-5693565|reactome:R-SCE-69473|reactome:R-SCE-69601|reactome:R-SCE-75035|ensemblfungi:YDL101C(gene)|ensemblfungi:YDL101C_mRNA(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0042770"(signal transduction in response to DNA damage)|go:"GO:0044773"(mitotic DNA damage checkpoint signaling)|go:"GO:0048478"(replication fork protection)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000253(Forkhead-associated)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:2JQJ|rcsb pdb:2JQL|sgd:YDL101C(identity)	refseq:NP_004413.1|ensembl:ENSG00000004975(gene)|ensembl:ENST00000005340(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005109"(frizzled binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0007507"(heart development)|go:"GO:0016235"(aggresome)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044340"(canonical Wnt signaling pathway involved in regulation of cell proliferation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0150012"(positive regulation of neuron projection arborization)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008341(Dishevelled-2 region)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:O14641|rcsb pdb:2REY|rcsb pdb:3CBX|rcsb pdb:3CBY|rcsb pdb:3CBZ|rcsb pdb:3CC0|rcsb pdb:4WIP|rcsb pdb:5LNP|rcsb pdb:5SUY|rcsb pdb:5SUZ|rcsb pdb:6IW3|rcsb pdb:6JCK|reactome:R-HSA-201681|reactome:R-HSA-201688|reactome:R-HSA-2028269|reactome:R-HSA-4086400|reactome:R-HSA-4608870|reactome:R-HSA-4641258|reactome:R-HSA-4641262|reactome:R-HSA-5099900|reactome:R-HSA-5368598|reactome:R-HSA-5663220|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9673324|ensembl:ENSP00000005340|dip:DIP-34433N|entrezgene/locuslink:1856(identity)	-	crc64:4990F24F024702D7	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:/BmlSDRdkj7efDRuXH/qWpdTv/U559292	rogid:2Vdc8oRnT4Mz/j+EXQXrL3AszOc9606	intact-crc:CA454B400BF2F85B|rigid:8ujev4UxGU6V0MpRNV9N7YEpg+E	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O00444	uniprotkb:P39009	intact:EBI-746202|uniprotkb:Q8IYF0|uniprotkb:Q96Q95|uniprotkb:B2RAL0|uniprotkb:B7Z837|uniprotkb:B7Z8G7|uniprotkb:Q9UD84|uniprotkb:Q9UDE2|ensembl:ENSP00000270861	intact:EBI-6194|uniprotkb:D6VRP9|ensemblfungi:YDL101C	psi-mi:plk4_human(display_long)|uniprotkb:Polo-like kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase Sak(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 18(gene name synonym)|uniprotkb:PLK4(gene name)|psi-mi:PLK4(display_short)|uniprotkb:SAK(gene name synonym)|uniprotkb:STK18(gene name synonym)	psi-mi:dun1_yeast(display_long)|uniprotkb:DUN1(gene name)|psi-mi:DUN1(display_short)|uniprotkb:D2370(orf name)|uniprotkb:YDL101C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11558934|imex:IM-24995-4782	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001177728.1|refseq:NP_001177730.1|refseq:NP_055079.3|dip:DIP-34467N|rcsb pdb:5LHZ|rcsb pdb:6N45|rcsb pdb:6N46|rcsb pdb:6W38|rcsb pdb:6W3I|rcsb pdb:6W3J|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|rcsb pdb:5LHY|reactome:R-HSA-5620912|reactome:R-HSA-8854518|ensembl:ENSG00000142731(gene)|ensembl:ENST00000270861(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0001741"(XY body)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007099"(centriole replication)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0046601"(positive regulation of centriole replication)|go:"GO:0060271"(cilium assembly)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0098535"(de novo centriole assembly involved in multi-ciliated epithelial cell differentiation)|go:"GO:0098536"(deuterosome)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033696|interpro:IPR033698|interpro:IPR033699|interpro:IPR033700|mint:O00444|rcsb pdb:2N19|rcsb pdb:3COK|rcsb pdb:4JXF|rcsb pdb:4N7V|rcsb pdb:4N7Z|rcsb pdb:4N9J|rcsb pdb:4YUR|rcsb pdb:4YYP|entrezgene/locuslink:10733(identity)	refseq:NP_010182.1|sgd:S000002259|dip:DIP-1772N|reactome:R-SCE-5693565|reactome:R-SCE-69473|reactome:R-SCE-69601|reactome:R-SCE-75035|ensemblfungi:YDL101C(gene)|ensemblfungi:YDL101C_mRNA(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0042770"(signal transduction in response to DNA damage)|go:"GO:0044773"(mitotic DNA damage checkpoint signaling)|go:"GO:0048478"(replication fork protection)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000253(Forkhead-associated)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:2JQJ|rcsb pdb:2JQL|sgd:YDL101C(identity)	-	-	crc64:4990F24F024702D7	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:xqjVEnoGXDk/+2AzLRAkyPK80OI9606	rogid:/BmlSDRdkj7efDRuXH/qWpdTv/U559292	intact-crc:7F492B8A466B26C3|rigid:3TXIx6nf/xaNuijN+DIwGHgtYHI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38991	uniprotkb:P63279	intact:EBI-9319|ensemblfungi:YPL209C|uniprotkb:D6W3G1	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	psi-mi:ipl1_yeast(display_long)|uniprotkb:IPL1(gene name)|psi-mi:IPL1(display_short)|uniprotkb:YPL209C(locus name)|uniprotkb:Aurora kinase(gene name synonym)|uniprotkb:Increase-in-ploidy protein 1(gene name synonym)	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11558925|imex:IM-24995-4781	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YPL209C(gene)|ensemblfungi:YPL209C_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005828"(kinetochore microtubule)|go:"GO:0005874"(microtubule)|go:"GO:0005876"(spindle microtubule)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008608"(attachment of spindle microtubules to kinetochore)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0032133"(chromosome passenger complex)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0035174"(histone serine kinase activity)|go:"GO:0044774"(mitotic DNA integrity checkpoint signaling)|go:"GO:0045143"(homologous chromosome segregation)|go:"GO:0045144"(meiotic sister chromatid segregation)|go:"GO:0051228"(mitotic spindle disassembly)|go:"GO:0051233"(spindle midzone)|go:"GO:0090266"(regulation of mitotic cell cycle spindle assembly checkpoint)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901673"(regulation of mitotic spindle assembly)|go:"GO:1901925"(negative regulation of protein import into nucleus during spindle assembly checkpoint)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR030616|reactome:R-SCE-8854050|refseq:NP_015115.1|sgd:S000006130|dip:DIP-2771N|mint:P38991|sgd:YPL209C(identity)	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N|entrezgene/locuslink:7329(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:hNg/pnDWxuP6BSpguV7aFh50wtE559292	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	intact-crc:DAC3CF42BAE0C101|rigid:6iS+zoUtLDyAWkBXjVkV2AjXdmg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38986	uniprotkb:Q96IK5	intact:EBI-3014|uniprotkb:D6VSV3|ensemblfungi:YDR321W	intact:EBI-2548508|ensembl:ENSP00000282570|uniprotkb:Q9H826|uniprotkb:Q9H8V7|uniprotkb:Q9H927	psi-mi:aspg1_yeast(display_long)|uniprotkb:YDR321W(locus name)|uniprotkb:D9798.6(orf name)|uniprotkb:ASP1(gene name)|psi-mi:ASP1(display_short)|uniprotkb:L-asparaginase I(gene name synonym)|uniprotkb:L-asparagine amidohydrolase I(gene name synonym)	psi-mi:gmcl1_human(display_long)|uniprotkb:GMCL1(gene name)|psi-mi:GMCL1(display_short)|uniprotkb:GCL(gene name synonym)|uniprotkb:BTBD13(gene name synonym)|uniprotkb:SPATA29(gene name synonym)|uniprotkb:Spermatogenesis-associated protein 29(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11558916|imex:IM-24995-4780	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002729|refseq:NP_010607.3|dip:DIP-4030N|mint:P38986|ensemblfungi:YDR321W(gene)|ensemblfungi:YDR321W_mRNA(transcript)|go:"GO:0004067"(asparaginase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006530"(asparagine catabolic process)|go:"GO:0042597"(periplasmic space)|interpro:IPR004550(L-asparaginase, type II)|interpro:IPR006034(Asparaginase/glutaminase)|interpro:IPR020827|interpro:IPR027473|interpro:IPR027474|interpro:IPR027475|interpro:IPR036152|interpro:IPR037152|interpro:IPR040919|sgd:YDR321W(identity)	ensembl:ENSG00000087338(gene)|ensembl:ENST00000282570(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0007281"(germ cell development)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016363"(nuclear matrix)|go:"GO:0042802"(identical protein binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR043380|refseq:NP_848526.1|entrezgene/locuslink:64395(identity)	-	crc64:8204CB7C58B5B75F	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:vIy3riBmCKfYQjsh3cIcO7o1Bzw559292	rogid:ED8yqySVu7BWxpw3DUSNBZSQWrk9606	intact-crc:2BF18680AFEB5F49|rigid:oy943M8+iFCiGMpW9GCtR8GGXvI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P63279	uniprotkb:P38986	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	intact:EBI-3014|uniprotkb:D6VSV3|ensemblfungi:YDR321W	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:aspg1_yeast(display_long)|uniprotkb:YDR321W(locus name)|uniprotkb:D9798.6(orf name)|uniprotkb:ASP1(gene name)|psi-mi:ASP1(display_short)|uniprotkb:L-asparaginase I(gene name synonym)|uniprotkb:L-asparagine amidohydrolase I(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11558907|imex:IM-24995-4779	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N|entrezgene/locuslink:7329(identity)	sgd:S000002729|refseq:NP_010607.3|dip:DIP-4030N|mint:P38986|ensemblfungi:YDR321W(gene)|ensemblfungi:YDR321W_mRNA(transcript)|go:"GO:0004067"(asparaginase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006530"(asparagine catabolic process)|go:"GO:0042597"(periplasmic space)|interpro:IPR004550(L-asparaginase, type II)|interpro:IPR006034(Asparaginase/glutaminase)|interpro:IPR020827|interpro:IPR027473|interpro:IPR027474|interpro:IPR027475|interpro:IPR036152|interpro:IPR037152|interpro:IPR040919|sgd:YDR321W(identity)	-	-	crc64:8204CB7C58B5B75F	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	rogid:vIy3riBmCKfYQjsh3cIcO7o1Bzw559292	intact-crc:2387C74CEFDD5721|rigid:5tyG65EjXp2hDPPyg7E12KfBvvE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O14777	uniprotkb:P39518	intact:EBI-715849|uniprotkb:Q6PJX2|ensembl:ENSP00000261597	intact:EBI-10082|uniprotkb:D3DLR3|ensemblfungi:YER015W	psi-mi:ndc80_human(display_long)|uniprotkb:Kinetochore protein Hec1(gene name synonym)|uniprotkb:Kinetochore-associated protein 2(gene name synonym)|uniprotkb:Highly expressed in cancer protein(gene name synonym)|uniprotkb:Retinoblastoma-associated protein HEC(gene name synonym)|uniprotkb:NDC80(gene name)|psi-mi:NDC80(display_short)|uniprotkb:HEC(gene name synonym)|uniprotkb:KNTC2(gene name synonym)|uniprotkb:HEC1(gene name synonym)	psi-mi:lcf2_yeast(display_long)|uniprotkb:YER015W(locus name)|uniprotkb:FAA2(gene name)|psi-mi:FAA2(display_short)|uniprotkb:FAM1(gene name synonym)|uniprotkb:Long-chain acyl-CoA synthetase 2(gene name synonym)|uniprotkb:Fatty acid activator 2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11558989|imex:IM-24995-4788	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006092.1|ensembl:ENSG00000080986(gene)|ensembl:ENST00000261597(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000940"(outer kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008608"(attachment of spindle microtubules to kinetochore)|go:"GO:0016020"(membrane)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051298"(centrosome duplication)|go:"GO:0051301"(cell division)|go:"GO:0051310"(metaphase plate congression)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051383"(kinetochore organization)|go:"GO:0090267"(positive regulation of mitotic cell cycle spindle assembly checkpoint)|go:"GO:1905342"(positive regulation of protein localization to kinetochore)|interpro:IPR005550(HEC/Ndc80p)|interpro:IPR038273|interpro:IPR040967|mint:O14777|rcsb pdb:2IGP|rcsb pdb:2VE7|rcsb pdb:3IZ0|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|dip:DIP-35100N|entrezgene/locuslink:10403(identity)	sgd:S000000817|ensemblfungi:YER015W_mRNA(transcript)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0004467"(long-chain fatty acid-CoA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0015910"(long-chain fatty acid import into peroxisome)|go:"GO:0015916"(fatty-acyl-CoA transport)|go:"GO:0016020"(membrane)|go:"GO:0031956"(medium-chain fatty acid-CoA ligase activity)|go:"GO:0031957"(very long-chain fatty acid-CoA ligase activity)|go:"GO:0042760"(very long-chain fatty acid catabolic process)|go:"GO:0102391"(decanoate-CoA ligase activity)|ensemblfungi:YER015W(gene)|interpro:IPR020845|interpro:IPR000873(AMP-dependent synthetase and ligase)|reactome:R-SCE-75876|refseq:NP_010931.3|dip:DIP-6565N|sgd:YER015W(identity)	-	-	crc64:1E023C18682805BC	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:5OsXbZPvJTMWPepp7M+AXlJUQ649606	rogid:N0W+wPvCsl01y0k8hJZ156LztOo559292	intact-crc:6195A4E57649D9DC|rigid:1gnk8ybQrgiQ3DaBb+Wo4SQgyjc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P39518	uniprotkb:O00635	intact:EBI-10082|uniprotkb:D3DLR3|ensemblfungi:YER015W	intact:EBI-2130415|uniprotkb:B2R862|ensembl:ENSP00000349596	psi-mi:lcf2_yeast(display_long)|uniprotkb:YER015W(locus name)|uniprotkb:FAA2(gene name)|psi-mi:FAA2(display_short)|uniprotkb:FAM1(gene name synonym)|uniprotkb:Long-chain acyl-CoA synthetase 2(gene name synonym)|uniprotkb:Fatty acid activator 2(gene name synonym)	psi-mi:tri38_human(display_long)|uniprotkb:TRIM38(gene name)|psi-mi:TRIM38(display_short)|uniprotkb:RNF15(gene name synonym)|uniprotkb:RORET(gene name synonym)|uniprotkb:RING finger protein 15(gene name synonym)|uniprotkb:Zinc finger protein RoRet(gene name synonym)|uniprotkb:Tripartite motif-containing protein 38(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM38(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11558980|imex:IM-24995-4787	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000000817|ensemblfungi:YER015W_mRNA(transcript)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0004467"(long-chain fatty acid-CoA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0015910"(long-chain fatty acid import into peroxisome)|go:"GO:0015916"(fatty-acyl-CoA transport)|go:"GO:0016020"(membrane)|go:"GO:0031956"(medium-chain fatty acid-CoA ligase activity)|go:"GO:0031957"(very long-chain fatty acid-CoA ligase activity)|go:"GO:0042760"(very long-chain fatty acid catabolic process)|go:"GO:0102391"(decanoate-CoA ligase activity)|ensemblfungi:YER015W(gene)|interpro:IPR020845|interpro:IPR000873(AMP-dependent synthetase and ligase)|reactome:R-SCE-75876|refseq:NP_010931.3|dip:DIP-6565N|sgd:YER015W(identity)	refseq:NP_006346.1|refseq:XP_005248856.1|refseq:XP_005248857.1|ensembl:ENSG00000112343(gene)|ensembl:ENST00000357085(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046598"(positive regulation of viral entry into host cell)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR035790|interpro:IPR043136|reactome:R-HSA-877300|entrezgene/locuslink:10475(identity)	-	crc64:1E023C18682805BC	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:N0W+wPvCsl01y0k8hJZ156LztOo559292	rogid:Zh4X/6v/qKZlDkMV6hhn7OsvPnQ9606	intact-crc:4363A8873364888B|rigid:DYAXS5I8rCUG/nH272qtRBbq/p8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P39078	uniprotkb:Q13287	intact:EBI-19054|uniprotkb:Q07561|uniprotkb:D6VRK5|ensemblfungi:YDL143W	intact:EBI-372942|uniprotkb:Q53TI8|intact:EBI-10174268|uniprotkb:Q8WTW2|uniprotkb:Q9BVE5|uniprotkb:B5BU69|ensembl:ENSP00000243346	psi-mi:tcpd_yeast(display_long)|uniprotkb:YDL143W(locus name)|uniprotkb:CCT4(gene name)|psi-mi:CCT4(display_short)|uniprotkb:ANC2(gene name synonym)|uniprotkb:TCP4(gene name synonym)|uniprotkb:CCT-delta(gene name synonym)	psi-mi:nmi_human(display_long)|uniprotkb:NMI(gene name)|psi-mi:NMI(display_short)|uniprotkb:N-myc and STAT interactor(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11558970|imex:IM-24995-4786	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010138.1|sgd:S000002302|ensemblfungi:YDL143W(gene)|ensemblfungi:YDL143W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0006457"(protein folding)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012717(T-complex protein 1, delta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|rcsb pdb:4V81|rcsb pdb:4V8R|rcsb pdb:4V94|rcsb pdb:5GW4|rcsb pdb:5GW5|rcsb pdb:6KRD|rcsb pdb:6KRE|rcsb pdb:6KS6|rcsb pdb:6KS7|rcsb pdb:6KS8|reactome:R-SCE-390471|reactome:R-SCE-6814122|dip:DIP-6753N|mint:P39078|sgd:YDL143W(identity)	refseq:NP_004679.2|refseq:XP_005246998.1|ensembl:ENSG00000123609(gene)|ensembl:ENST00000243346(transcript)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0032687"(negative regulation of interferon-alpha production)|go:"GO:0032688"(negative regulation of interferon-beta production)|go:"GO:0034142"(toll-like receptor 4 signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0045824"(negative regulation of innate immune response)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:1901223"(negative regulation of NIK/NF-kappaB signaling)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1902524"(positive regulation of protein K48-linked ubiquitination)|interpro:IPR009909(Nmi/IFP 35)|interpro:IPR009938(Interferon-induced 35 kDa, N-terminal)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033527|mint:Q13287|refseq:XP_016860736.1|entrezgene/locuslink:9111(identity)	-	crc64:F01146D76F4E850C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:GCSpoIEgtQxu/8dbncxp/4AXEls559292	rogid:qOkzIuloaWW88apb9JH2DT/Bnuk9606	intact-crc:3AD0A54F44FFFFB9|rigid:iQuVQOjFrxdRxUi15OftIUlJaN0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:A0A0C4DGF1	uniprotkb:P39014	intact:EBI-10188476|ensembl:ENSP00000433657	intact:EBI-11507|uniprotkb:D6VVN6|ensemblfungi:YIL046W	psi-mi:a0a0c4dgf1_human(display_long)|uniprotkb:ZBTB32(gene name)|psi-mi:ZBTB32(display_short)	psi-mi:met30_yeast(display_long)|uniprotkb:YIL046W(locus name)|uniprotkb:MET30(gene name)|psi-mi:MET30(display_short)|uniprotkb:Methionine-requiring protein 30(gene name synonym)|uniprotkb:"E3 ubiquitin ligase complex SCF(Met30) subunit MET30"(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11558961|imex:IM-24995-4785	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|ensembl:ENSG00000011590(gene)|ensembl:ENST00000481182(transcript)|go:"GO:0042802"(identical protein binding)|entrezgene/locuslink:27033(identity)	ensemblfungi:YIL046W_mRNA(transcript)|ensemblfungi:YIL046W(gene)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009086"(methionine biosynthetic process)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019344"(cysteine biosynthetic process)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043224"(nuclear SCF ubiquitin ligase complex)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0046686"(response to cadmium ion)|interpro:IPR001680(WD40 repeat)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036047|interpro:IPR036322|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|refseq:NP_012218.1|sgd:S000001308|mint:P39014|dip:DIP-1439N|sgd:YIL046W(identity)	-	-	crc64:5135D4BCA2E1EB97	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:w3k7YT4kw/T+Xi5YBqGHSpHtwMM9606	rogid:B138OcWsG8zW/eFMselD2pFyy5c559292	intact-crc:77E585F567DE9414|rigid:IXhuelB6Pd5JIjAYg+O/Vx1v0tM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O94972	uniprotkb:P39009	intact:EBI-741602|uniprotkb:Q7Z3E6|uniprotkb:Q8IYF7|uniprotkb:Q8WYF7|intact:EBI-28976055|ensembl:ENSP00000262294|ensembl:ENSP00000376785|uniprotkb:A8K0V9|uniprotkb:A8K8U4|uniprotkb:A8MZ79|uniprotkb:B4DGZ3|uniprotkb:F8WEE6	intact:EBI-6194|uniprotkb:D6VRP9|ensemblfungi:YDL101C	psi-mi:tri37_human(display_long)|uniprotkb:Mulibrey nanism protein(gene name synonym)|uniprotkb:TRIM37(gene name)|psi-mi:TRIM37(display_short)|uniprotkb:KIAA0898(gene name synonym)|uniprotkb:MUL(gene name synonym)|uniprotkb:POB1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 37(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM37(gene name synonym)	psi-mi:dun1_yeast(display_long)|uniprotkb:DUN1(gene name)|psi-mi:DUN1(display_short)|uniprotkb:D2370(orf name)|uniprotkb:YDL101C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11558952|imex:IM-24995-4784	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001005207.1|refseq:NP_056109.1|refseq:NP_001307916.1|ensembl:ENSP00000262294|ensembl:ENST00000393065|ensembl:ENSP00000376784|ensembl:ENSP00000376785|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046600"(negative regulation of centriole replication)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070842"(aggresome assembly)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002083(MATH)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR008974(TRAF-like)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR037299|rcsb pdb:3LRQ|reactome:R-HSA-983168|ensembl:ENSG00000108395(gene)|ensembl:ENST00000262294(transcript)|ensembl:ENST00000393066(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005777"(peroxisome)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016235"(aggresome)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0035518"(histone H2A monoubiquitination)|refseq:NP_001307919.1|dip:DIP-34437N|entrezgene/locuslink:4591(identity)	refseq:NP_010182.1|sgd:S000002259|dip:DIP-1772N|reactome:R-SCE-5693565|reactome:R-SCE-69473|reactome:R-SCE-69601|reactome:R-SCE-75035|ensemblfungi:YDL101C(gene)|ensemblfungi:YDL101C_mRNA(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0042770"(signal transduction in response to DNA damage)|go:"GO:0044773"(mitotic DNA damage checkpoint signaling)|go:"GO:0048478"(replication fork protection)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000253(Forkhead-associated)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:2JQJ|rcsb pdb:2JQL|sgd:YDL101C(identity)	-	-	crc64:4990F24F024702D7	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:y2njeO0MUBrKU9MUvkbo1uZmqkE9606	rogid:/BmlSDRdkj7efDRuXH/qWpdTv/U559292	intact-crc:CA9E3459497B2488|rigid:QR+AyAVHr6gXRTVaED8l3Arm+Xg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P39518	uniprotkb:P07910-2	intact:EBI-10082|uniprotkb:D3DLR3|ensemblfungi:YER015W	intact:EBI-5280084|ensembl:ENSP00000442816|ensembl:ENSP00000450544|ensembl:ENSP00000450725|ensembl:ENSP00000451176	psi-mi:lcf2_yeast(display_long)|uniprotkb:YER015W(locus name)|uniprotkb:FAA2(gene name)|psi-mi:FAA2(display_short)|uniprotkb:FAM1(gene name synonym)|uniprotkb:Long-chain acyl-CoA synthetase 2(gene name synonym)|uniprotkb:Fatty acid activator 2(gene name synonym)	psi-mi:p07910-2(display_long)|uniprotkb:HNRNPC(gene name)|psi-mi:HNRNPC(display_short)|uniprotkb:HNRPC(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11559025|imex:IM-24995-4792	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000000817|ensemblfungi:YER015W_mRNA(transcript)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0004467"(long-chain fatty acid-CoA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0015910"(long-chain fatty acid import into peroxisome)|go:"GO:0015916"(fatty-acyl-CoA transport)|go:"GO:0016020"(membrane)|go:"GO:0031956"(medium-chain fatty acid-CoA ligase activity)|go:"GO:0031957"(very long-chain fatty acid-CoA ligase activity)|go:"GO:0042760"(very long-chain fatty acid catabolic process)|go:"GO:0102391"(decanoate-CoA ligase activity)|ensemblfungi:YER015W(gene)|interpro:IPR020845|interpro:IPR000873(AMP-dependent synthetase and ligase)|reactome:R-SCE-75876|refseq:NP_010931.3|dip:DIP-6565N|sgd:YER015W(identity)	uniprotkb:P07910-2(isoform-parent)|intact:EBI-357966(isoform-parent)|ensembl:ENSG00000092199(gene)|ensembl:ENST00000430246(transcript)|ensembl:ENST00000553300(transcript)|ensembl:ENST00000554969(transcript)|ensembl:ENST00000556897(transcript)|entrezgene/locuslink:3183(identity)	-	crc64:1E023C18682805BC	isoform-comment:Contains a phosphoserine at position 107. Contains a phosphoserine at position 108.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:N0W+wPvCsl01y0k8hJZ156LztOo559292	rogid:r7AhGozE3aHdynLr8DrXPRtOuyI9606	intact-crc:21AF8ECC460BD77B|rigid:Yh1FrBuSQDLkgkAtbCm/laXsAgQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O96006	uniprotkb:P39518	intact:EBI-740037|uniprotkb:Q96BY4|ensembl:ENSP00000370616|ensembl:ENSP00000370620|ensembl:ENSP00000370621|ensembl:ENSP00000498725	intact:EBI-10082|uniprotkb:D3DLR3|ensemblfungi:YER015W	psi-mi:zbed1_human(display_long)|uniprotkb:ZBED1(gene name)|psi-mi:ZBED1(display_short)|uniprotkb:ALTE(gene name synonym)|uniprotkb:DREF(gene name synonym)|uniprotkb:KIAA0785(gene name synonym)|uniprotkb:TRAMP(gene name synonym)|uniprotkb:dREF homolog(gene name synonym)|uniprotkb:Putative Ac-like transposable element(gene name synonym)|uniprotkb:DNA replication-related element-binding factor(gene name synonym)|uniprotkb:Zinc finger BED domain-containing protein 1(gene name synonym)|uniprotkb:hDREF(gene name synonym)	psi-mi:lcf2_yeast(display_long)|uniprotkb:YER015W(locus name)|uniprotkb:FAA2(gene name)|psi-mi:FAA2(display_short)|uniprotkb:FAM1(gene name synonym)|uniprotkb:Long-chain acyl-CoA synthetase 2(gene name synonym)|uniprotkb:Fatty acid activator 2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11559016|imex:IM-24995-4791	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164606.1|refseq:NP_001164607.1|refseq:NP_004720.1|ensembl:ENSG00000214717(gene)|ensembl:ENST00000381218(transcript)|ensembl:ENST00000381222(transcript)|ensembl:ENST00000381223(transcript)|ensembl:ENST00000652001(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0031965"(nuclear membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044828"(negative regulation by host of viral genome replication)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0061665"(SUMO ligase activity)|go:"GO:1990466"(protein autosumoylation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003656(Zinc finger, BED-type predicted)|interpro:IPR008906(HAT dimerisation)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR036236|mint:O96006|rcsb pdb:2CT5|reactome:R-HSA-4551638|go:"GO:0005813"(centrosome)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016605"(PML body)|entrezgene/locuslink:9189(identity)	sgd:S000000817|ensemblfungi:YER015W_mRNA(transcript)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0004467"(long-chain fatty acid-CoA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0015910"(long-chain fatty acid import into peroxisome)|go:"GO:0015916"(fatty-acyl-CoA transport)|go:"GO:0016020"(membrane)|go:"GO:0031956"(medium-chain fatty acid-CoA ligase activity)|go:"GO:0031957"(very long-chain fatty acid-CoA ligase activity)|go:"GO:0042760"(very long-chain fatty acid catabolic process)|go:"GO:0102391"(decanoate-CoA ligase activity)|ensemblfungi:YER015W(gene)|interpro:IPR020845|interpro:IPR000873(AMP-dependent synthetase and ligase)|reactome:R-SCE-75876|refseq:NP_010931.3|dip:DIP-6565N|sgd:YER015W(identity)	-	-	crc64:1E023C18682805BC	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:jl97ZV2Kz5YAmQKktWt/wk7OkRw9606	rogid:N0W+wPvCsl01y0k8hJZ156LztOo559292	intact-crc:6B11EAAC490EDB4D|rigid:sZdkYiOSON76+GVlp5u9S9LSf58	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P39518	uniprotkb:O95197-3	intact:EBI-10082|uniprotkb:D3DLR3|ensemblfungi:YER015W	intact:EBI-11525735|ensembl:ENSP00000440874	psi-mi:lcf2_yeast(display_long)|uniprotkb:YER015W(locus name)|uniprotkb:FAA2(gene name)|psi-mi:FAA2(display_short)|uniprotkb:FAM1(gene name synonym)|uniprotkb:Long-chain acyl-CoA synthetase 2(gene name synonym)|uniprotkb:Fatty acid activator 2(gene name synonym)	psi-mi:o95197-3(display_long)|uniprotkb:RTN3(gene name)|psi-mi:RTN3(display_short)|uniprotkb:ASYIP(gene name synonym)|uniprotkb:Homolog of ASY protein(gene name synonym)|uniprotkb:NSPL2(gene name synonym)|uniprotkb:Neuroendocrine-specific protein-like 2(gene name synonym)|uniprotkb:Neuroendocrine-specific protein-like II(gene name synonym)|uniprotkb:A1(isoform synonym)|uniprotkb:B1(isoform synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11559007|imex:IM-24995-4790	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000000817|ensemblfungi:YER015W_mRNA(transcript)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0004467"(long-chain fatty acid-CoA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0015910"(long-chain fatty acid import into peroxisome)|go:"GO:0015916"(fatty-acyl-CoA transport)|go:"GO:0016020"(membrane)|go:"GO:0031956"(medium-chain fatty acid-CoA ligase activity)|go:"GO:0031957"(very long-chain fatty acid-CoA ligase activity)|go:"GO:0042760"(very long-chain fatty acid catabolic process)|go:"GO:0102391"(decanoate-CoA ligase activity)|ensemblfungi:YER015W(gene)|interpro:IPR020845|interpro:IPR000873(AMP-dependent synthetase and ligase)|reactome:R-SCE-75876|refseq:NP_010931.3|dip:DIP-6565N|sgd:YER015W(identity)	ensembl:ENSG00000133318(gene)|ensembl:ENST00000537981(transcript)|intact:EBI-740467(isoform-parent)|uniprotkb:O95197-3(isoform-parent)|entrezgene/locuslink:10313(identity)	-	crc64:1E023C18682805BC	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:N0W+wPvCsl01y0k8hJZ156LztOo559292	rogid:+TJnANu85CM52dRZ6s+hYMlUABE9606	intact-crc:287F8286572F955E|rigid:x+n4ZW7+LM8GqBUsDoGUzPA9Vc8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O76083-2	uniprotkb:P39518	intact:EBI-11524542|ensembl:ENSP00000335242	intact:EBI-10082|uniprotkb:D3DLR3|ensemblfungi:YER015W	psi-mi:o76083-2(display_long)|uniprotkb:PDE9A(gene name)|psi-mi:PDE9A(display_short)	psi-mi:lcf2_yeast(display_long)|uniprotkb:YER015W(locus name)|uniprotkb:FAA2(gene name)|psi-mi:FAA2(display_short)|uniprotkb:FAM1(gene name synonym)|uniprotkb:Long-chain acyl-CoA synthetase 2(gene name synonym)|uniprotkb:Fatty acid activator 2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11558998|imex:IM-24995-4789	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-742764(isoform-parent)|ensembl:ENSG00000160191(gene)|ensembl:ENST00000335512(transcript)|uniprotkb:O76083-2(isoform-parent)|entrezgene/locuslink:5152(identity)	sgd:S000000817|ensemblfungi:YER015W_mRNA(transcript)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0004467"(long-chain fatty acid-CoA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0015910"(long-chain fatty acid import into peroxisome)|go:"GO:0015916"(fatty-acyl-CoA transport)|go:"GO:0016020"(membrane)|go:"GO:0031956"(medium-chain fatty acid-CoA ligase activity)|go:"GO:0031957"(very long-chain fatty acid-CoA ligase activity)|go:"GO:0042760"(very long-chain fatty acid catabolic process)|go:"GO:0102391"(decanoate-CoA ligase activity)|ensemblfungi:YER015W(gene)|interpro:IPR020845|interpro:IPR000873(AMP-dependent synthetase and ligase)|reactome:R-SCE-75876|refseq:NP_010931.3|dip:DIP-6565N|sgd:YER015W(identity)	-	-	crc64:1E023C18682805BC	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:nTzgeYGOwTM/7VJUgxSnlnDiCFo9606	rogid:N0W+wPvCsl01y0k8hJZ156LztOo559292	intact-crc:156F402C4E4FFDD9|rigid:Dk/8xP4LKaNsYTJltvWK8HDs5Js	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q13422-7	uniprotkb:P39518	intact:EBI-11522367|ensembl:ENSP00000352123|ensembl:ENSP00000413025	intact:EBI-10082|uniprotkb:D3DLR3|ensemblfungi:YER015W	psi-mi:q13422-7(display_long)|uniprotkb:IKZF1(gene name)|psi-mi:IKZF1(display_short)|uniprotkb:IK1(gene name synonym)|uniprotkb:IKAROS(gene name synonym)|uniprotkb:Ikaros family zinc finger protein 1(gene name synonym)|uniprotkb:LYF1(gene name synonym)|uniprotkb:Lymphoid transcription factor LyF-1(gene name synonym)|uniprotkb:ZNFN1A1(gene name synonym)	psi-mi:lcf2_yeast(display_long)|uniprotkb:YER015W(locus name)|uniprotkb:FAA2(gene name)|psi-mi:FAA2(display_short)|uniprotkb:FAM1(gene name synonym)|uniprotkb:Long-chain acyl-CoA synthetase 2(gene name synonym)|uniprotkb:Fatty acid activator 2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11559072|imex:IM-24995-4797	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-745305(isoform-parent)|ensembl:ENSG00000185811(gene)|ensembl:ENST00000359197(transcript)|ensembl:ENST00000439701(transcript)|uniprotkb:Q13422-7(isoform-parent)|entrezgene/locuslink:10320(identity)	sgd:S000000817|ensemblfungi:YER015W_mRNA(transcript)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0004467"(long-chain fatty acid-CoA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0015910"(long-chain fatty acid import into peroxisome)|go:"GO:0015916"(fatty-acyl-CoA transport)|go:"GO:0016020"(membrane)|go:"GO:0031956"(medium-chain fatty acid-CoA ligase activity)|go:"GO:0031957"(very long-chain fatty acid-CoA ligase activity)|go:"GO:0042760"(very long-chain fatty acid catabolic process)|go:"GO:0102391"(decanoate-CoA ligase activity)|ensemblfungi:YER015W(gene)|interpro:IPR020845|interpro:IPR000873(AMP-dependent synthetase and ligase)|reactome:R-SCE-75876|refseq:NP_010931.3|dip:DIP-6565N|sgd:YER015W(identity)	-	-	crc64:1E023C18682805BC	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:ou/ovXYoMneBNVp4pj38VxenfyY9606	rogid:N0W+wPvCsl01y0k8hJZ156LztOo559292	intact-crc:92ED483F2DAD2431|rigid:tr2RoegfWLDzWC6PNjVH9qBlufc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P39518	uniprotkb:Q13137	intact:EBI-10082|uniprotkb:D3DLR3|ensemblfungi:YER015W	intact:EBI-739580|uniprotkb:B4DDC4|uniprotkb:E7ENK0|uniprotkb:Q53FQ5|uniprotkb:Q53HB5|uniprotkb:Q6IBN9|uniprotkb:Q9BTF7|uniprotkb:B2RBT0|ensembl:ENSP00000258947|uniprotkb:B4E0C0|uniprotkb:E7ETP5|uniprotkb:B4DDT4|uniprotkb:B4DP36|uniprotkb:E9PBE5	psi-mi:lcf2_yeast(display_long)|uniprotkb:YER015W(locus name)|uniprotkb:FAA2(gene name)|psi-mi:FAA2(display_short)|uniprotkb:FAM1(gene name synonym)|uniprotkb:Long-chain acyl-CoA synthetase 2(gene name synonym)|uniprotkb:Fatty acid activator 2(gene name synonym)	psi-mi:caco2_human(display_long)|uniprotkb:CALCOCO2(gene name)|psi-mi:CALCOCO2(display_short)|uniprotkb:NDP52(gene name synonym)|uniprotkb:Nuclear domain 10 protein NDP52(gene name synonym)|uniprotkb:Antigen nuclear dot 52 kDa protein(gene name synonym)|uniprotkb:Nuclear dot protein 52(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11559063|imex:IM-24995-4796	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000000817|ensemblfungi:YER015W_mRNA(transcript)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0004467"(long-chain fatty acid-CoA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0015910"(long-chain fatty acid import into peroxisome)|go:"GO:0015916"(fatty-acyl-CoA transport)|go:"GO:0016020"(membrane)|go:"GO:0031956"(medium-chain fatty acid-CoA ligase activity)|go:"GO:0031957"(very long-chain fatty acid-CoA ligase activity)|go:"GO:0042760"(very long-chain fatty acid catabolic process)|go:"GO:0102391"(decanoate-CoA ligase activity)|ensemblfungi:YER015W(gene)|interpro:IPR020845|interpro:IPR000873(AMP-dependent synthetase and ligase)|reactome:R-SCE-75876|refseq:NP_010931.3|dip:DIP-6565N|sgd:YER015W(identity)	refseq:NP_001248319.1|refseq:NP_001248320.1|refseq:NP_001248322.1|refseq:NP_005822.1|ensembl:ENSG00000136436(gene)|ensembl:ENST00000258947(transcript)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016032"(viral process)|go:"GO:0016605"(PML body)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0098792"(xenophagy)|go:"GO:1901098"(positive regulation of autophagosome maturation)|interpro:IPR041611|interpro:IPR041641|mint:Q13137|rcsb pdb:2MXP|rcsb pdb:3VVV|rcsb pdb:3VVW|rcsb pdb:4GXL|rcsb pdb:4HAN|rcsb pdb:4XKL|rcsb pdb:5AAQ|rcsb pdb:5Z7A|rcsb pdb:5Z7L|refseq:NP_001248324.1|dip:DIP-57534N|entrezgene/locuslink:10241(identity)	-	crc64:1E023C18682805BC	crc64:609B121DA1A9DCB8	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:N0W+wPvCsl01y0k8hJZ156LztOo559292	rogid:N/GPJUGBK+Dh5Cg+csmafphuo9M9606	intact-crc:9EC0FBB0E0DF09C2|rigid:JuBP4SQdwbjIksL/sT7y/Ft556A	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P39518	uniprotkb:P49902	intact:EBI-10082|uniprotkb:D3DLR3|ensemblfungi:YER015W	intact:EBI-742084|uniprotkb:Q5JUV5|uniprotkb:D3DR91|ensembl:ENSP00000339479|ensembl:ENSP00000383960|ensembl:ENSP00000501689|ensembl:ENSP00000502205|ensembl:ENSP00000502679|ensembl:ENSP00000502801|uniprotkb:B7Z382	psi-mi:lcf2_yeast(display_long)|uniprotkb:YER015W(locus name)|uniprotkb:FAA2(gene name)|psi-mi:FAA2(display_short)|uniprotkb:FAM1(gene name synonym)|uniprotkb:Long-chain acyl-CoA synthetase 2(gene name synonym)|uniprotkb:Fatty acid activator 2(gene name synonym)	psi-mi:5ntc_human(display_long)|uniprotkb:Cytosolic 5'-nucleotidase II(gene name synonym)|uniprotkb:NT5C2(gene name)|psi-mi:NT5C2(display_short)|uniprotkb:NT5B(gene name synonym)|uniprotkb:NT5CP(gene name synonym)|uniprotkb:PNT5(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11559054|imex:IM-24995-4795	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000000817|ensemblfungi:YER015W_mRNA(transcript)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0004467"(long-chain fatty acid-CoA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0015910"(long-chain fatty acid import into peroxisome)|go:"GO:0015916"(fatty-acyl-CoA transport)|go:"GO:0016020"(membrane)|go:"GO:0031956"(medium-chain fatty acid-CoA ligase activity)|go:"GO:0031957"(very long-chain fatty acid-CoA ligase activity)|go:"GO:0042760"(very long-chain fatty acid catabolic process)|go:"GO:0102391"(decanoate-CoA ligase activity)|ensemblfungi:YER015W(gene)|interpro:IPR020845|interpro:IPR000873(AMP-dependent synthetase and ligase)|reactome:R-SCE-75876|refseq:NP_010931.3|dip:DIP-6565N|sgd:YER015W(identity)	ensembl:ENST00000675326(transcript)|refseq:NP_001127845.1|refseq:NP_036361.1|ensembl:ENSG00000076685(gene)|ensembl:ENST00000343289(transcript)|ensembl:ENST00000404739(transcript)|ensembl:ENST00000674696(transcript)|ensembl:ENST00000676449(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0005829"(cytosol)|go:"GO:0006204"(IMP catabolic process)|go:"GO:0008253"(5'-nucleotidase activity)|go:"GO:0019428"(allantoin biosynthetic process)|go:"GO:0046040"(IMP metabolic process)|go:"GO:0046085"(adenosine metabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0050483"(IMP 5'-nucleotidase activity)|interpro:IPR008380(HAD-superfamily hydrolase, subfamily IG, 5'-nucleotidase)|interpro:IPR016695(Purine 5'-nucleotidase)|interpro:IPR023214|interpro:IPR036412|mint:P49902|rcsb pdb:2J2C|rcsb pdb:2JC9|rcsb pdb:2JCM|rcsb pdb:2XCV|rcsb pdb:2XCW|rcsb pdb:2XCX|rcsb pdb:2XJB|rcsb pdb:2XJC|rcsb pdb:2XJD|rcsb pdb:2XJE|rcsb pdb:2XJF|rcsb pdb:4H4B|rcsb pdb:5CQZ|rcsb pdb:5CR7|rcsb pdb:5K7Y|rcsb pdb:5L4Z|rcsb pdb:5L50|rcsb pdb:5OPK|rcsb pdb:5OPL|rcsb pdb:5OPM|rcsb pdb:5OPN|rcsb pdb:5OPO|rcsb pdb:5OPP|rcsb pdb:6DD3|rcsb pdb:6DDB|rcsb pdb:6DDC|rcsb pdb:6DDH|rcsb pdb:6DDK|rcsb pdb:6DDL|ensembl:ENST00000676428(transcript)|rcsb pdb:6DDO|rcsb pdb:6DDQ|rcsb pdb:6DDX|rcsb pdb:6DDY|rcsb pdb:6DDZ|rcsb pdb:6DE0|rcsb pdb:6DE1|rcsb pdb:6DE2|rcsb pdb:6DE3|rcsb pdb:6FIR|rcsb pdb:6FIS|rcsb pdb:6FIU|rcsb pdb:6FIW|rcsb pdb:6FXH|reactome:R-HSA-2161541|reactome:R-HSA-74259|refseq:XP_005269693.1|refseq:XP_005269696.1|entrezgene/locuslink:22978(identity)	-	crc64:1E023C18682805BC	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:N0W+wPvCsl01y0k8hJZ156LztOo559292	rogid:5CDp+/pOJ1IRk/ndDr4SGP0Ext89606	intact-crc:6EF46F63FDD4046E|rigid:W9yB3Ioq/6qjAeSCgael0VrS98k	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P39518	uniprotkb:P35520	intact:EBI-10082|uniprotkb:D3DLR3|ensemblfungi:YER015W	intact:EBI-740135|uniprotkb:Q99425|uniprotkb:Q9BWC5|uniprotkb:B2R993|uniprotkb:D3DSK4|intact:EBI-14245939|ensembl:ENSP00000344460|ensembl:ENSP00000352643|ensembl:ENSP00000381225|ensembl:ENSP00000381231	psi-mi:lcf2_yeast(display_long)|uniprotkb:YER015W(locus name)|uniprotkb:FAA2(gene name)|psi-mi:FAA2(display_short)|uniprotkb:FAM1(gene name synonym)|uniprotkb:Long-chain acyl-CoA synthetase 2(gene name synonym)|uniprotkb:Fatty acid activator 2(gene name synonym)	psi-mi:cbs_human(display_long)|uniprotkb:CBS(gene name)|psi-mi:CBS(display_short)|uniprotkb:Serine sulfhydrase(gene name synonym)|uniprotkb:Beta-thionase(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11559044|imex:IM-24995-4794	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000000817|ensemblfungi:YER015W_mRNA(transcript)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0004467"(long-chain fatty acid-CoA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0015910"(long-chain fatty acid import into peroxisome)|go:"GO:0015916"(fatty-acyl-CoA transport)|go:"GO:0016020"(membrane)|go:"GO:0031956"(medium-chain fatty acid-CoA ligase activity)|go:"GO:0031957"(very long-chain fatty acid-CoA ligase activity)|go:"GO:0042760"(very long-chain fatty acid catabolic process)|go:"GO:0102391"(decanoate-CoA ligase activity)|ensemblfungi:YER015W(gene)|interpro:IPR020845|interpro:IPR000873(AMP-dependent synthetase and ligase)|reactome:R-SCE-75876|refseq:NP_010931.3|dip:DIP-6565N|sgd:YER015W(identity)	refseq:NP_000062.1|refseq:NP_001171479.1|refseq:NP_001171480.1|ensembl:ENSG00000160200(gene)|ensembl:ENST00000352178(transcript)|ensembl:ENST00000359624(transcript)|ensembl:ENST00000398158(transcript)|go:"GO:0004122"(cystathionine beta-synthase activity)|ensembl:ENST00000398165(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006535"(cysteine biosynthetic process from serine)|go:"GO:0006563"(L-serine metabolic process)|go:"GO:0006565"(L-serine catabolic process)|go:"GO:0019343"(cysteine biosynthetic process via cystathionine)|go:"GO:0019344"(cysteine biosynthetic process)|go:"GO:0019346"(transsulfuration)|go:"GO:0019448"(L-cysteine catabolic process)|go:"GO:0019825"(oxygen binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0020037"(heme binding)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042262"(DNA protection)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043418"(homocysteine catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0050421"("nitrite reductase (NO-forming) activity")|go:"GO:0050667"(homocysteine metabolic process)|go:"GO:0070025"(carbon monoxide binding)|go:"GO:0070026"(nitric oxide binding)|go:"GO:0070814"(hydrogen sulfide biosynthetic process)|go:"GO:0072341"(modified amino acid binding)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR001216(Cysteine synthase/cystathionine beta-synthase P-phosphate-binding site)|interpro:IPR001926(Pyridoxal phosphate-dependent enzyme, beta subunit)|interpro:IPR005857(Cystathionine beta-synthase)|interpro:IPR036052|mint:P35520|rcsb pdb:1JBQ|rcsb pdb:1M54|rcsb pdb:4COO|rcsb pdb:4L0D|rcsb pdb:4L27|rcsb pdb:4L28|rcsb pdb:4L3V|rcsb pdb:4PCU|rcsb pdb:4UUU|rcsb pdb:5MMS|reactome:R-HSA-1614603|reactome:R-HSA-2408508|refseq:XP_011528079.1|refseq:XP_011528083.1|refseq:XP_011528084.1|refseq:XP_011544396.1|refseq:XP_011544397.1|refseq:XP_011544399.1|refseq:XP_011544400.1|refseq:XP_011544401.1|refseq:NP_001307227.1|refseq:NP_001308002.1|refseq:XP_016883700.1|refseq:XP_016883701.1|refseq:XP_016883702.1|refseq:XP_016883703.1|refseq:XP_016883704.1|refseq:XP_016883705.1|refseq:XP_016883706.1|refseq:XP_016883707.1|refseq:XP_016883978.1|refseq:XP_016883979.1|refseq:XP_016883980.1|refseq:XP_016883981.1|entrezgene/locuslink:875(identity)	-	crc64:1E023C18682805BC	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:N0W+wPvCsl01y0k8hJZ156LztOo559292	rogid:f9eo0cPOHppVY7Nqejag3YyK18s9606	intact-crc:456E0432E23095D8|rigid:ngkmAHGpWOuDy4j3IBLXuwd8SN4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P22234	uniprotkb:P39518	intact:EBI-712261|ensembl:ENSP00000264221|ensembl:ENSP00000421096|uniprotkb:E9PDH9|uniprotkb:Q68CQ5|intact:EBI-21352784	intact:EBI-10082|uniprotkb:D3DLR3|ensemblfungi:YER015W	psi-mi:pur6_human(display_long)|uniprotkb:PAICS(gene name)|psi-mi:PAICS(display_short)|uniprotkb:ADE2(gene name synonym)|uniprotkb:AIRC(gene name synonym)|uniprotkb:PAIS(gene name synonym)	psi-mi:lcf2_yeast(display_long)|uniprotkb:YER015W(locus name)|uniprotkb:FAA2(gene name)|psi-mi:FAA2(display_short)|uniprotkb:FAM1(gene name synonym)|uniprotkb:Long-chain acyl-CoA synthetase 2(gene name synonym)|uniprotkb:Fatty acid activator 2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11559035|imex:IM-24995-4793	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000128050(gene)|ensembl:ENST00000264221(transcript)|ensembl:ENST00000512576(transcript)|go:"GO:0004639"(phosphoribosylaminoimidazolesuccinocarboxamide synthase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006189"('de novo' IMP biosynthetic process)|go:"GO:0009113"(purine nucleobase biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043727"(5-amino-4-imidazole carboxylate lyase activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000031("1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase")|interpro:IPR018236|interpro:IPR028923|interpro:IPR033626|mint:P22234|rcsb pdb:2H31|rcsb pdb:6YB8|go:"GO:0004638"(phosphoribosylaminoimidazole carboxylase activity)|rcsb pdb:6YB9|reactome:R-HSA-73817|refseq:NP_001072992.1|refseq:NP_001072993.1|refseq:NP_006443.1|entrezgene/locuslink:10606(identity)	sgd:S000000817|ensemblfungi:YER015W_mRNA(transcript)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0004467"(long-chain fatty acid-CoA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0015910"(long-chain fatty acid import into peroxisome)|go:"GO:0015916"(fatty-acyl-CoA transport)|go:"GO:0016020"(membrane)|go:"GO:0031956"(medium-chain fatty acid-CoA ligase activity)|go:"GO:0031957"(very long-chain fatty acid-CoA ligase activity)|go:"GO:0042760"(very long-chain fatty acid catabolic process)|go:"GO:0102391"(decanoate-CoA ligase activity)|ensemblfungi:YER015W(gene)|interpro:IPR020845|interpro:IPR000873(AMP-dependent synthetase and ligase)|reactome:R-SCE-75876|refseq:NP_010931.3|dip:DIP-6565N|sgd:YER015W(identity)	-	-	crc64:1E023C18682805BC	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:aR4Xj14ZQrPiY8cldw5o9AvjkAo9606	rogid:N0W+wPvCsl01y0k8hJZ156LztOo559292	intact-crc:D737375E218F0A83|rigid:XQYQO3vd7kUaC61bqXSD4A5ow5k	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8N7W2-2	uniprotkb:P39518	intact:EBI-10181188|ensembl:ENSP00000367868	intact:EBI-10082|uniprotkb:D3DLR3|ensemblfungi:YER015W	psi-mi:q8n7w2-2(display_long)|uniprotkb:C10orf30(gene name synonym)|uniprotkb:BEND7(gene name)|psi-mi:BEND7(display_short)	psi-mi:lcf2_yeast(display_long)|uniprotkb:YER015W(locus name)|uniprotkb:FAA2(gene name)|psi-mi:FAA2(display_short)|uniprotkb:FAM1(gene name synonym)|uniprotkb:Long-chain acyl-CoA synthetase 2(gene name synonym)|uniprotkb:Fatty acid activator 2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11559101|imex:IM-24995-4800	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000165626(gene)|ensembl:ENST00000378605(transcript)|intact:EBI-743382(isoform-parent)|uniprotkb:Q8N7W2-2(isoform-parent)|entrezgene/locuslink:222389(identity)	sgd:S000000817|ensemblfungi:YER015W_mRNA(transcript)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0004467"(long-chain fatty acid-CoA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0015910"(long-chain fatty acid import into peroxisome)|go:"GO:0015916"(fatty-acyl-CoA transport)|go:"GO:0016020"(membrane)|go:"GO:0031956"(medium-chain fatty acid-CoA ligase activity)|go:"GO:0031957"(very long-chain fatty acid-CoA ligase activity)|go:"GO:0042760"(very long-chain fatty acid catabolic process)|go:"GO:0102391"(decanoate-CoA ligase activity)|ensemblfungi:YER015W(gene)|interpro:IPR020845|interpro:IPR000873(AMP-dependent synthetase and ligase)|reactome:R-SCE-75876|refseq:NP_010931.3|dip:DIP-6565N|sgd:YER015W(identity)	-	-	crc64:1E023C18682805BC	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:p6qrTn80hLyVU0W2Tvwn50Q4m5I9606	rogid:N0W+wPvCsl01y0k8hJZ156LztOo559292	intact-crc:FC69AB57E3EC95BF|rigid:EjK37wZoiPafiy8nv3vpz9zYSac	false	sufficient binding region:10-374	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P39518	uniprotkb:Q8IUQ4-2	intact:EBI-10082|uniprotkb:D3DLR3|ensemblfungi:YER015W	intact:EBI-11522811|ensembl:ENSP00000349156	psi-mi:lcf2_yeast(display_long)|uniprotkb:YER015W(locus name)|uniprotkb:FAA2(gene name)|psi-mi:FAA2(display_short)|uniprotkb:FAM1(gene name synonym)|uniprotkb:Long-chain acyl-CoA synthetase 2(gene name synonym)|uniprotkb:Fatty acid activator 2(gene name synonym)	psi-mi:q8iuq4-2(display_long)|uniprotkb:SIAH1(gene name)|psi-mi:SIAH1(display_short)|uniprotkb:HUMSIAH(gene name synonym)|uniprotkb:Seven in absentia homolog 1(gene name synonym)|uniprotkb:Siah-1a(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase SIAH1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11559090|imex:IM-24995-4799	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000000817|ensemblfungi:YER015W_mRNA(transcript)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0004467"(long-chain fatty acid-CoA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0015910"(long-chain fatty acid import into peroxisome)|go:"GO:0015916"(fatty-acyl-CoA transport)|go:"GO:0016020"(membrane)|go:"GO:0031956"(medium-chain fatty acid-CoA ligase activity)|go:"GO:0031957"(very long-chain fatty acid-CoA ligase activity)|go:"GO:0042760"(very long-chain fatty acid catabolic process)|go:"GO:0102391"(decanoate-CoA ligase activity)|ensemblfungi:YER015W(gene)|interpro:IPR020845|interpro:IPR000873(AMP-dependent synthetase and ligase)|reactome:R-SCE-75876|refseq:NP_010931.3|dip:DIP-6565N|sgd:YER015W(identity)	intact:EBI-747107(isoform-parent)|ensembl:ENSG00000196470(gene)|ensembl:ENST00000356721(transcript)|uniprotkb:Q8IUQ4-2(isoform-parent)|entrezgene/locuslink:6477(identity)	-	crc64:1E023C18682805BC	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:N0W+wPvCsl01y0k8hJZ156LztOo559292	rogid:M4q06jVbWuq1mGMXvtuFBaMEgZM9606	intact-crc:B9D73E8477F9B1B3|rigid:QY3qRKX+Ly4iEvVnVLbkyovBdqQ	false	-	sufficient binding region:32-313	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q15041	uniprotkb:P39518	intact:EBI-714543|ensembl:ENSP00000306788|uniprotkb:B7Z6S5|uniprotkb:B7Z791|uniprotkb:F5GXP4	intact:EBI-10082|uniprotkb:D3DLR3|ensemblfungi:YER015W	psi-mi:ar6p1_human(display_long)|uniprotkb:ARL6IP(gene name synonym)|uniprotkb:ARL6IP1(gene name)|psi-mi:ARL6IP1(display_short)|uniprotkb:KIAA0069(gene name synonym)|uniprotkb:ARMER(gene name synonym)|uniprotkb:Apoptotic regulator in the membrane of the endoplasmic reticulum(gene name synonym)	psi-mi:lcf2_yeast(display_long)|uniprotkb:YER015W(locus name)|uniprotkb:FAA2(gene name)|psi-mi:FAA2(display_short)|uniprotkb:FAM1(gene name synonym)|uniprotkb:Long-chain acyl-CoA synthetase 2(gene name synonym)|uniprotkb:Fatty acid activator 2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11559081|imex:IM-24995-4798	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055976.1|ensembl:ENSG00000170540(gene)|ensembl:ENST00000304414(transcript)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006613"(cotranslational protein targeting to membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0071787"(endoplasmic reticulum tubular network formation)|go:"GO:1903371"(regulation of endoplasmic reticulum tubular network organization)|go:"GO:1990809"(endoplasmic reticulum tubular network membrane organization)|interpro:IPR033301|mint:Q15041|go:"GO:0002038"(positive regulation of L-glutamate import across plasma membrane)|refseq:NP_001300787.1|entrezgene/locuslink:23204(identity)	sgd:S000000817|ensemblfungi:YER015W_mRNA(transcript)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0004467"(long-chain fatty acid-CoA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0015910"(long-chain fatty acid import into peroxisome)|go:"GO:0015916"(fatty-acyl-CoA transport)|go:"GO:0016020"(membrane)|go:"GO:0031956"(medium-chain fatty acid-CoA ligase activity)|go:"GO:0031957"(very long-chain fatty acid-CoA ligase activity)|go:"GO:0042760"(very long-chain fatty acid catabolic process)|go:"GO:0102391"(decanoate-CoA ligase activity)|ensemblfungi:YER015W(gene)|interpro:IPR020845|interpro:IPR000873(AMP-dependent synthetase and ligase)|reactome:R-SCE-75876|refseq:NP_010931.3|dip:DIP-6565N|sgd:YER015W(identity)	-	-	crc64:1E023C18682805BC	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:3fjkoyvUx25po7xsPcXgpjEeLJg9606	rogid:N0W+wPvCsl01y0k8hJZ156LztOo559292	intact-crc:3BD1A5CF5D2A44C7|rigid:ov9rVkwnhLHkf4vKK1snMQdp5sY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9BSE2	uniprotkb:P39547	intact:EBI-8649725|ensembl:ENSP00000295694|ensembl:ENSP00000384748|intact:MINT-8163648|uniprotkb:D3DVB8|uniprotkb:B2RE22	intact:EBI-20760|uniprotkb:D6VPM9|ensemblfungi:YAR027W	psi-mi:tmm79_human(display_long)|uniprotkb:MATT(gene name synonym)|uniprotkb:TMEM79(gene name)|psi-mi:TMEM79(display_short)|uniprotkb:Mattrin(gene name synonym)	psi-mi:uip3_yeast(display_long)|uniprotkb:UIP3(gene name)|psi-mi:UIP3(display_short)|uniprotkb:YAR027W(locus name)|uniprotkb:FUN55(orf name)|uniprotkb:DUP240 protein UIP3(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11559148|imex:IM-24995-4805	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000163472(gene)|ensembl:ENST00000295694(transcript)|ensembl:ENST00000405535(transcript)|go:"GO:0002070"(epithelial cell maturation)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031069"(hair follicle morphogenesis)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0042335"(cuticle development)|go:"GO:0042802"(identical protein binding)|go:"GO:0045055"(regulated exocytosis)|go:"GO:0045684"(positive regulation of epidermis development)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070268"(cornification)|mint:Q9BSE2|refseq:NP_115699.1|entrezgene/locuslink:84283(identity)	sgd:S000000075|refseq:NP_009414.1|ensemblfungi:YAR027W(gene)|ensemblfungi:YAR027W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031965"(nuclear membrane)|interpro:IPR001142(Yeast membrane protein DUP)|dip:DIP-2031N|sgd:YAR027W(identity)	-	comment:mint	crc64:9DBF29F9C2395AB2	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:QdmILKEdTJzJUhBdigw/4vC4R3o9606	rogid:2Eb82iBxbdvlroWw/nM4BQeiVIc559292	intact-crc:C1285EE81A63F5DF|rigid:9DZxVoVQDjwUMiByyxSNbVWEbJ0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P39518	uniprotkb:Q9UI14	intact:EBI-10082|uniprotkb:D3DLR3|ensemblfungi:YER015W	intact:EBI-712367|ensembl:ENSP00000222008|uniprotkb:Q7Z4Y2|uniprotkb:Q9Y3R1	psi-mi:lcf2_yeast(display_long)|uniprotkb:YER015W(locus name)|uniprotkb:FAA2(gene name)|psi-mi:FAA2(display_short)|uniprotkb:FAM1(gene name synonym)|uniprotkb:Long-chain acyl-CoA synthetase 2(gene name synonym)|uniprotkb:Fatty acid activator 2(gene name synonym)	psi-mi:praf1_human(display_long)|uniprotkb:PRA1 family protein 1(gene name synonym)|uniprotkb:RABAC1(gene name)|psi-mi:RABAC1(display_short)|uniprotkb:PRA1(gene name synonym)|uniprotkb:PRAF1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11559139|imex:IM-24995-4804	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000000817|ensemblfungi:YER015W_mRNA(transcript)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0004467"(long-chain fatty acid-CoA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0015910"(long-chain fatty acid import into peroxisome)|go:"GO:0015916"(fatty-acyl-CoA transport)|go:"GO:0016020"(membrane)|go:"GO:0031956"(medium-chain fatty acid-CoA ligase activity)|go:"GO:0031957"(very long-chain fatty acid-CoA ligase activity)|go:"GO:0042760"(very long-chain fatty acid catabolic process)|go:"GO:0102391"(decanoate-CoA ligase activity)|ensemblfungi:YER015W(gene)|interpro:IPR020845|interpro:IPR000873(AMP-dependent synthetase and ligase)|reactome:R-SCE-75876|refseq:NP_010931.3|dip:DIP-6565N|sgd:YER015W(identity)	refseq:NP_006414.2|ensembl:ENSG00000105404(gene)|ensembl:ENST00000222008(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0070064"(proline-rich region binding)|interpro:IPR004895(Prenylated rab acceptor PRA1)|mint:Q9UI14|entrezgene/locuslink:10567(identity)	-	crc64:1E023C18682805BC	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:N0W+wPvCsl01y0k8hJZ156LztOo559292	rogid:WS2rUY7yXRbR7pqWgfUCbnEiDbg9606	intact-crc:696F73B997AEF944|rigid:jPhhAt1Bsy7WNtT3Ax4kIVJhUQo	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P39518	uniprotkb:Q9NPJ6	intact:EBI-10082|uniprotkb:D3DLR3|ensemblfungi:YER015W	intact:EBI-394607|uniprotkb:Q9BS95|uniprotkb:Q9NYR5|uniprotkb:Q53GB4|uniprotkb:Q53H68|uniprotkb:Q5T912|uniprotkb:Q6FHC4|uniprotkb:Q6IA79|uniprotkb:B4DX67|ensembl:ENSP00000258648	psi-mi:lcf2_yeast(display_long)|uniprotkb:YER015W(locus name)|uniprotkb:FAA2(gene name)|psi-mi:FAA2(display_short)|uniprotkb:FAM1(gene name synonym)|uniprotkb:Long-chain acyl-CoA synthetase 2(gene name synonym)|uniprotkb:Fatty acid activator 2(gene name synonym)	psi-mi:med4_human(display_long)|uniprotkb:HSPC126(orf name)|uniprotkb:DRIP36(gene name synonym)|uniprotkb:MED4(gene name)|psi-mi:MED4(display_short)|uniprotkb:ARC36(gene name synonym)|uniprotkb:Mediator complex subunit 4(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex 36 kDa component(gene name synonym)|uniprotkb:Activator-recruited cofactor 36 kDa component(gene name synonym)|uniprotkb:TRAP/SMCC/PC2 subunit p36 subunit(gene name synonym)|uniprotkb:VDRIP(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11559130|imex:IM-24995-4803	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000000817|ensemblfungi:YER015W_mRNA(transcript)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0004467"(long-chain fatty acid-CoA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0015910"(long-chain fatty acid import into peroxisome)|go:"GO:0015916"(fatty-acyl-CoA transport)|go:"GO:0016020"(membrane)|go:"GO:0031956"(medium-chain fatty acid-CoA ligase activity)|go:"GO:0031957"(very long-chain fatty acid-CoA ligase activity)|go:"GO:0042760"(very long-chain fatty acid catabolic process)|go:"GO:0102391"(decanoate-CoA ligase activity)|ensemblfungi:YER015W(gene)|interpro:IPR020845|interpro:IPR000873(AMP-dependent synthetase and ligase)|reactome:R-SCE-75876|refseq:NP_010931.3|dip:DIP-6565N|sgd:YER015W(identity)	refseq:NP_001257558.1|refseq:NP_054885.1|ensembl:ENSG00000136146(gene)|ensembl:ENST00000258648(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0070847"(core mediator complex)|interpro:IPR019258|mint:Q9NPJ6|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|entrezgene/locuslink:29079(identity)	-	crc64:1E023C18682805BC	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:N0W+wPvCsl01y0k8hJZ156LztOo559292	rogid:Bept2Oec50gruA9e4pf+eEUiANM9606	intact-crc:C9EA66F4C79E331D|rigid:i1z/5yTyyQ+u3OtNUB+vUE5MzCI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96KN7-4	uniprotkb:P39518	intact:EBI-11525164|ensembl:ENSP00000372391	intact:EBI-10082|uniprotkb:D3DLR3|ensemblfungi:YER015W	psi-mi:q96kn7-4(display_long)|uniprotkb:RPGRIP1(gene name)|psi-mi:RPGRIP1(display_short)	psi-mi:lcf2_yeast(display_long)|uniprotkb:YER015W(locus name)|uniprotkb:FAA2(gene name)|psi-mi:FAA2(display_short)|uniprotkb:FAM1(gene name synonym)|uniprotkb:Long-chain acyl-CoA synthetase 2(gene name synonym)|uniprotkb:Fatty acid activator 2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11559121|imex:IM-24995-4802	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-1050213(isoform-parent)|ensembl:ENSG00000092200(gene)|ensembl:ENST00000382933(transcript)|uniprotkb:Q96KN7-4(isoform-parent)|entrezgene/locuslink:57096(identity)	sgd:S000000817|ensemblfungi:YER015W_mRNA(transcript)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0004467"(long-chain fatty acid-CoA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0015910"(long-chain fatty acid import into peroxisome)|go:"GO:0015916"(fatty-acyl-CoA transport)|go:"GO:0016020"(membrane)|go:"GO:0031956"(medium-chain fatty acid-CoA ligase activity)|go:"GO:0031957"(very long-chain fatty acid-CoA ligase activity)|go:"GO:0042760"(very long-chain fatty acid catabolic process)|go:"GO:0102391"(decanoate-CoA ligase activity)|ensemblfungi:YER015W(gene)|interpro:IPR020845|interpro:IPR000873(AMP-dependent synthetase and ligase)|reactome:R-SCE-75876|refseq:NP_010931.3|dip:DIP-6565N|sgd:YER015W(identity)	-	-	crc64:1E023C18682805BC	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Xy0433uM/nWhWLM/EsfESPJDIy49606	rogid:N0W+wPvCsl01y0k8hJZ156LztOo559292	intact-crc:FC9D12455E76E49C|rigid:/6AjyN53VR+VGsZRy2aKUCAVJLw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P39518	uniprotkb:Q96BR9	intact:EBI-10082|uniprotkb:D3DLR3|ensemblfungi:YER015W	intact:EBI-742740|uniprotkb:Q8IUL5|uniprotkb:Q8IWR9|uniprotkb:Q8N2Y5|uniprotkb:Q96BX0|ensembl:ENSP00000362609	psi-mi:lcf2_yeast(display_long)|uniprotkb:YER015W(locus name)|uniprotkb:FAA2(gene name)|psi-mi:FAA2(display_short)|uniprotkb:FAM1(gene name synonym)|uniprotkb:Long-chain acyl-CoA synthetase 2(gene name synonym)|uniprotkb:Fatty acid activator 2(gene name synonym)	psi-mi:zbt8a_human(display_long)|uniprotkb:ZBTB8A(gene name)|psi-mi:ZBTB8A(display_short)|uniprotkb:BOZF1(gene name synonym)|uniprotkb:BTB/POZ and zinc-finger domain-containing factor(gene name synonym)|uniprotkb:BTB/POZ and zinc-finger domains factor on chromosome 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11559112|imex:IM-24995-4801	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000000817|ensemblfungi:YER015W_mRNA(transcript)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0004467"(long-chain fatty acid-CoA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0015910"(long-chain fatty acid import into peroxisome)|go:"GO:0015916"(fatty-acyl-CoA transport)|go:"GO:0016020"(membrane)|go:"GO:0031956"(medium-chain fatty acid-CoA ligase activity)|go:"GO:0031957"(very long-chain fatty acid-CoA ligase activity)|go:"GO:0042760"(very long-chain fatty acid catabolic process)|go:"GO:0102391"(decanoate-CoA ligase activity)|ensemblfungi:YER015W(gene)|interpro:IPR020845|interpro:IPR000873(AMP-dependent synthetase and ligase)|reactome:R-SCE-75876|refseq:NP_010931.3|dip:DIP-6565N|sgd:YER015W(identity)	ensembl:ENSG00000160062(gene)|ensembl:ENST00000373510(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|refseq:NP_001035531.2|refseq:NP_001278425.1|entrezgene/locuslink:653121(identity)	-	crc64:1E023C18682805BC	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:N0W+wPvCsl01y0k8hJZ156LztOo559292	rogid:tsrPT2tHvuBryODKgRXnceXz9s09606	intact-crc:A5288E056179A2BD|rigid:Gr/sWGuaQeQTACIYn7TXknaBu6k	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P39682	uniprotkb:Q96MA1	intact:EBI-612|uniprotkb:D6VZC9|uniprotkb:E9P8Z1|ensemblfungi:YML046W	intact:EBI-954466|uniprotkb:Q96SD2|ensembl:ENSP00000360500	psi-mi:prp39_yeast(display_long)|uniprotkb:YM9827.06(orf name)|uniprotkb:YML046W(locus name)|uniprotkb:PRP39(gene name)|psi-mi:PRP39(display_short)	psi-mi:dmrtb_human(display_long)|uniprotkb:DMRTB1(gene name)|psi-mi:DMRTB1(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11559175|imex:IM-24995-4808	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013667.1|sgd:S000004509|dip:DIP-812N|mint:P39682|ensemblfungi:YML046W(gene)|ensemblfungi:YML046W_mRNA(transcript)|go:"GO:0000243"(commitment complex)|go:"GO:0000395"(mRNA 5'-splice site recognition)|go:"GO:0005685"(U1 snRNP)|go:"GO:0071004"(U2-type prespliceosome)|interpro:IPR003107(RNA-processing protein, HAT helix)|interpro:IPR011990(Tetratricopeptide-like helical)|rcsb pdb:5ZWN|rcsb pdb:6G90|rcsb pdb:6N7P|rcsb pdb:6N7R|rcsb pdb:6N7X|sgd:YML046W(identity)	go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|ensembl:ENSG00000143006(gene)|ensembl:ENST00000371445(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007281"(germ cell development)|go:"GO:0007548"(sex differentiation)|go:"GO:0046872"(metal ion binding)|interpro:IPR001275(DM DNA-binding)|interpro:IPR026607|interpro:IPR036407|mint:Q96MA1|refseq:NP_149056.1|ensembl:ENSP00000360500|entrezgene/locuslink:63948(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:urVLzQFKnYT1bYOs3yRd9dd7lMk559292	rogid:GU1xgsv/Oyy91PEorOlxBqAvIzc9606	intact-crc:4BF8EC70AD928D5F|rigid:FUMZ+VXl/dUFXcBRRDFQsjRZQLA	false	-	sufficient binding region:154-342	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P39682	uniprotkb:P31249	intact:EBI-612|uniprotkb:D6VZC9|uniprotkb:E9P8Z1|ensemblfungi:YML046W	intact:EBI-3957655|ensembl:ENSP00000249440|ensembl:ENSP00000386498|ensembl:ENSP00000507129|uniprotkb:Q99955|uniprotkb:Q9BSC5	psi-mi:prp39_yeast(display_long)|uniprotkb:YM9827.06(orf name)|uniprotkb:YML046W(locus name)|uniprotkb:PRP39(gene name)|psi-mi:PRP39(display_short)	psi-mi:hxd3_human(display_long)|uniprotkb:HOXD3(gene name)|psi-mi:HOXD3(display_short)|uniprotkb:HOX1D(gene name synonym)|uniprotkb:HOX4A(gene name synonym)|uniprotkb:Homeobox protein Hox-4A(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11559166|imex:IM-24995-4807	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013667.1|sgd:S000004509|dip:DIP-812N|mint:P39682|ensemblfungi:YML046W(gene)|ensemblfungi:YML046W_mRNA(transcript)|go:"GO:0000243"(commitment complex)|go:"GO:0000395"(mRNA 5'-splice site recognition)|go:"GO:0005685"(U1 snRNP)|go:"GO:0071004"(U2-type prespliceosome)|interpro:IPR003107(RNA-processing protein, HAT helix)|interpro:IPR011990(Tetratricopeptide-like helical)|rcsb pdb:5ZWN|rcsb pdb:6G90|rcsb pdb:6N7P|rcsb pdb:6N7R|rcsb pdb:6N7X|sgd:YML046W(identity)	ensembl:ENSG00000128652(gene)|ensembl:ENST00000249440(transcript)|ensembl:ENST00000410016(transcript)|ensembl:ENST00000683222(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016235"(aggresome)|go:"GO:0016604"(nuclear body)|go:"GO:0030878"(thyroid gland development)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0051216"(cartilage development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001827(Homeobox protein, antennapedia type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR025281|reactome:R-HSA-5617472|refseq:XP_011509367.1|refseq:XP_011509368.1|refseq:NP_008829.3|refseq:XP_005246566.1|refseq:XP_005246567.1|refseq:XP_005246568.1|refseq:XP_005246570.1|refseq:XP_006712540.1|entrezgene/locuslink:3232(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:urVLzQFKnYT1bYOs3yRd9dd7lMk559292	rogid:6egSlcCWXDnEWbOnwNGI/0ZxBM49606	intact-crc:713F80DCE0EFD579|rigid:lHvJJ2aYGlXmwZMSAt4SgWVhhbU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O14641	uniprotkb:P39682	intact:EBI-740850|ensembl:ENSP00000005340|uniprotkb:Q53XM0|uniprotkb:D3DTN3	intact:EBI-612|uniprotkb:D6VZC9|uniprotkb:E9P8Z1|ensemblfungi:YML046W	psi-mi:dvl2_human(display_long)|uniprotkb:DSH homolog 2(gene name synonym)|uniprotkb:DVL2(gene name)|psi-mi:DVL2(display_short)	psi-mi:prp39_yeast(display_long)|uniprotkb:YM9827.06(orf name)|uniprotkb:YML046W(locus name)|uniprotkb:PRP39(gene name)|psi-mi:PRP39(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11559157|imex:IM-24995-4806	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004413.1|ensembl:ENSG00000004975(gene)|ensembl:ENST00000005340(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005109"(frizzled binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0007507"(heart development)|go:"GO:0016235"(aggresome)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044340"(canonical Wnt signaling pathway involved in regulation of cell proliferation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0150012"(positive regulation of neuron projection arborization)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008341(Dishevelled-2 region)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:O14641|rcsb pdb:2REY|rcsb pdb:3CBX|rcsb pdb:3CBY|rcsb pdb:3CBZ|rcsb pdb:3CC0|rcsb pdb:4WIP|rcsb pdb:5LNP|rcsb pdb:5SUY|rcsb pdb:5SUZ|rcsb pdb:6IW3|rcsb pdb:6JCK|reactome:R-HSA-201681|reactome:R-HSA-201688|reactome:R-HSA-2028269|reactome:R-HSA-4086400|reactome:R-HSA-4608870|reactome:R-HSA-4641258|reactome:R-HSA-4641262|reactome:R-HSA-5099900|reactome:R-HSA-5368598|reactome:R-HSA-5663220|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9673324|ensembl:ENSP00000005340|dip:DIP-34433N|entrezgene/locuslink:1856(identity)	refseq:NP_013667.1|sgd:S000004509|dip:DIP-812N|mint:P39682|ensemblfungi:YML046W(gene)|ensemblfungi:YML046W_mRNA(transcript)|go:"GO:0000243"(commitment complex)|go:"GO:0000395"(mRNA 5'-splice site recognition)|go:"GO:0005685"(U1 snRNP)|go:"GO:0071004"(U2-type prespliceosome)|interpro:IPR003107(RNA-processing protein, HAT helix)|interpro:IPR011990(Tetratricopeptide-like helical)|rcsb pdb:5ZWN|rcsb pdb:6G90|rcsb pdb:6N7P|rcsb pdb:6N7R|rcsb pdb:6N7X|sgd:YML046W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:2Vdc8oRnT4Mz/j+EXQXrL3AszOc9606	rogid:urVLzQFKnYT1bYOs3yRd9dd7lMk559292	intact-crc:EBF9E39F0B8F0F53|rigid:Pfvm9smdLdGgF8hkioD1aRn7hOQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UHX1-5	uniprotkb:P39682	intact:EBI-11526420|ensembl:ENSP00000395417|ensembl:ENSP00000478209	intact:EBI-612|uniprotkb:D6VZC9|uniprotkb:E9P8Z1|ensemblfungi:YML046W	psi-mi:q9uhx1-5(display_long)|uniprotkb:PUF60(gene name)|psi-mi:PUF60(display_short)|uniprotkb:"60 kDa poly(U)-binding-splicing factor"(gene name synonym)|uniprotkb:FIR(gene name synonym)|uniprotkb:FUSE-binding protein-interacting repressor(gene name synonym)|uniprotkb:ROBPI(gene name synonym)|uniprotkb:Ro-binding protein 1(gene name synonym)|uniprotkb:SIAHBP1(gene name synonym)|uniprotkb:Siah-binding protein 1(gene name synonym)	psi-mi:prp39_yeast(display_long)|uniprotkb:YM9827.06(orf name)|uniprotkb:YML046W(locus name)|uniprotkb:PRP39(gene name)|psi-mi:PRP39(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11559213|imex:IM-24995-4812	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-1053259(isoform-parent)|ensembl:ENSG00000179950(gene)|ensembl:ENSG00000274081(gene)|ensembl:ENST00000456095(transcript)|ensembl:ENST00000620953(transcript)|entrezgene/locuslink:22827(identity)	refseq:NP_013667.1|sgd:S000004509|dip:DIP-812N|mint:P39682|ensemblfungi:YML046W(gene)|ensemblfungi:YML046W_mRNA(transcript)|go:"GO:0000243"(commitment complex)|go:"GO:0000395"(mRNA 5'-splice site recognition)|go:"GO:0005685"(U1 snRNP)|go:"GO:0071004"(U2-type prespliceosome)|interpro:IPR003107(RNA-processing protein, HAT helix)|interpro:IPR011990(Tetratricopeptide-like helical)|rcsb pdb:5ZWN|rcsb pdb:6G90|rcsb pdb:6N7P|rcsb pdb:6N7R|rcsb pdb:6N7X|sgd:YML046W(identity)	-	isoform-comment:"Contains a glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) at position 14."	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:PSbIU++DIL6ysF0ccd3ZHzeJ5rs9606	rogid:urVLzQFKnYT1bYOs3yRd9dd7lMk559292	intact-crc:2FA0A875A492BA26|rigid:Spa7EzJSdtfwuHn1cV5zMiXBmgs	false	sufficient binding region:15-530	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P39682	uniprotkb:Q9UHX1-2	intact:EBI-612|uniprotkb:D6VZC9|uniprotkb:E9P8Z1|ensemblfungi:YML046W	intact:EBI-11529177|ensembl:ENSP00000322036|ensembl:ENSP00000478495	psi-mi:prp39_yeast(display_long)|uniprotkb:YM9827.06(orf name)|uniprotkb:YML046W(locus name)|uniprotkb:PRP39(gene name)|psi-mi:PRP39(display_short)	psi-mi:q9uhx1-2(display_long)|uniprotkb:PUF60(gene name)|psi-mi:PUF60(display_short)|uniprotkb:"60 kDa poly(U)-binding-splicing factor"(gene name synonym)|uniprotkb:FIR(gene name synonym)|uniprotkb:FUSE-binding protein-interacting repressor(gene name synonym)|uniprotkb:ROBPI(gene name synonym)|uniprotkb:Ro-binding protein 1(gene name synonym)|uniprotkb:SIAHBP1(gene name synonym)|uniprotkb:Siah-binding protein 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11559204|imex:IM-24995-4811	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013667.1|sgd:S000004509|dip:DIP-812N|mint:P39682|ensemblfungi:YML046W(gene)|ensemblfungi:YML046W_mRNA(transcript)|go:"GO:0000243"(commitment complex)|go:"GO:0000395"(mRNA 5'-splice site recognition)|go:"GO:0005685"(U1 snRNP)|go:"GO:0071004"(U2-type prespliceosome)|interpro:IPR003107(RNA-processing protein, HAT helix)|interpro:IPR011990(Tetratricopeptide-like helical)|rcsb pdb:5ZWN|rcsb pdb:6G90|rcsb pdb:6N7P|rcsb pdb:6N7R|rcsb pdb:6N7X|sgd:YML046W(identity)	intact:EBI-1053259(isoform-parent)|ensembl:ENSG00000179950(gene)|ensembl:ENSG00000274081(gene)|ensembl:ENST00000349157(transcript)|ensembl:ENST00000612237(transcript)|uniprotkb:Q9UHX1-2(isoform-parent)|entrezgene/locuslink:22827(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:urVLzQFKnYT1bYOs3yRd9dd7lMk559292	rogid:snVN9Lw5+MP2/aiq4z08ANwvr209606	intact-crc:2B11616CE639F6A7|rigid:C3+tQHyQVRHPL3u5/4qmzT1w/iw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P39682	uniprotkb:Q9P2A4	intact:EBI-612|uniprotkb:D6VZC9|uniprotkb:E9P8Z1|ensemblfungi:YML046W	intact:EBI-742038|uniprotkb:C9IZN8|ensembl:ENSP00000225941|uniprotkb:Q9H0P6	psi-mi:prp39_yeast(display_long)|uniprotkb:YM9827.06(orf name)|uniprotkb:YML046W(locus name)|uniprotkb:PRP39(gene name)|psi-mi:PRP39(display_short)	psi-mi:abi3_human(display_long)|uniprotkb:New molecule including SH3(gene name synonym)|uniprotkb:ABI3(gene name)|psi-mi:ABI3(display_short)|uniprotkb:NESH(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11559195|imex:IM-24995-4810	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013667.1|sgd:S000004509|dip:DIP-812N|mint:P39682|ensemblfungi:YML046W(gene)|ensemblfungi:YML046W_mRNA(transcript)|go:"GO:0000243"(commitment complex)|go:"GO:0000395"(mRNA 5'-splice site recognition)|go:"GO:0005685"(U1 snRNP)|go:"GO:0071004"(U2-type prespliceosome)|interpro:IPR003107(RNA-processing protein, HAT helix)|interpro:IPR011990(Tetratricopeptide-like helical)|rcsb pdb:5ZWN|rcsb pdb:6G90|rcsb pdb:6N7P|rcsb pdb:6N7R|rcsb pdb:6N7X|sgd:YML046W(identity)	refseq:NP_001128658.1|refseq:NP_057512.1|ensembl:ENSG00000108798(gene)|ensembl:ENST00000225941(transcript)|go:"GO:0002357"(defense response to tumor cell)|go:"GO:0005737"(cytoplasm)|go:"GO:0010593"(negative regulation of lamellipodium assembly)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031209"(SCAR complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0051015"(actin filament binding)|go:"GO:0061001"(regulation of dendritic spine morphogenesis)|go:"GO:0099151"(regulation of postsynaptic density assembly)|go:"GO:1900028"(negative regulation of ruffle assembly)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|go:"GO:2000249"(regulation of actin cytoskeleton reorganization)|go:"GO:2000774"(positive regulation of cellular senescence)|interpro:IPR001452(Src homology-3)|interpro:IPR012849(Abl-interactor, homeo-domain homologous region)|interpro:IPR028455|interpro:IPR028457|interpro:IPR036028|mint:Q9P2A4|entrezgene/locuslink:51225(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:urVLzQFKnYT1bYOs3yRd9dd7lMk559292	rogid:VAjz40ulLa5L+GmfL7ia5wTDND49606	intact-crc:135AC67369E231A8|rigid:UCLOxnRR+nFmXuBy6ddfW7m0mDc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9NSC5	uniprotkb:P39682	intact:EBI-748420|uniprotkb:O14580|uniprotkb:O95350|uniprotkb:Q9NSB9|uniprotkb:Q9NSC0|intact:EBI-2557809|uniprotkb:E9PCW9|uniprotkb:Q9NSC1|intact:EBI-28972925|ensembl:ENSP00000376162|ensembl:ENSP00000439937|ensembl:ENSP00000446026|intact:EBI-10175777|uniprotkb:B2RA10	intact:EBI-612|uniprotkb:D6VZC9|uniprotkb:E9P8Z1|ensemblfungi:YML046W	psi-mi:home3_human(display_long)|uniprotkb:HOMER3(gene name)|psi-mi:HOMER3(display_short)	psi-mi:prp39_yeast(display_long)|uniprotkb:YM9827.06(orf name)|uniprotkb:YML046W(locus name)|uniprotkb:PRP39(gene name)|psi-mi:PRP39(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11559186|imex:IM-24995-4809	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000221222|ensembl:ENSP00000221222|ensembl:ENSP00000376162|ensembl:ENST00000433218|ensembl:ENSP00000396154|ensembl:ENSP00000439937|ensembl:ENSP00000446026|ensembl:ENST00000594439|ensembl:ENSP00000471835|refseq:XP_006723006.1|refseq:XP_006723007.1|refseq:NP_001139193.1|refseq:NP_001139194.1|refseq:NP_004829.3|refseq:NP_001139196.1|ensembl:ENSG00000051128(gene)|ensembl:ENST00000392351(transcript)|ensembl:ENST00000539827(transcript)|ensembl:ENST00000542541(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006605"(protein targeting)|go:"GO:0007216"(G protein-coupled glutamate receptor signaling pathway)|go:"GO:0014069"(postsynaptic density)|go:"GO:0030425"(dendrite)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0035256"(G protein-coupled glutamate receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|go:"GO:2001256"(regulation of store-operated calcium entry)|interpro:IPR000697(EVH1)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR044100|mint:Q9NSC5|rcsb pdb:2P8V|rcsb pdb:3CVF|reactome:R-HSA-6794361|entrezgene/locuslink:9454(identity)	refseq:NP_013667.1|sgd:S000004509|dip:DIP-812N|mint:P39682|ensemblfungi:YML046W(gene)|ensemblfungi:YML046W_mRNA(transcript)|go:"GO:0000243"(commitment complex)|go:"GO:0000395"(mRNA 5'-splice site recognition)|go:"GO:0005685"(U1 snRNP)|go:"GO:0071004"(U2-type prespliceosome)|interpro:IPR003107(RNA-processing protein, HAT helix)|interpro:IPR011990(Tetratricopeptide-like helical)|rcsb pdb:5ZWN|rcsb pdb:6G90|rcsb pdb:6N7P|rcsb pdb:6N7R|rcsb pdb:6N7X|sgd:YML046W(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:U1y/y52nnf7zQUCNQlqk7JDgXi49606	rogid:urVLzQFKnYT1bYOs3yRd9dd7lMk559292	intact-crc:F24EFBEB2B1A0861|rigid:PoE+zlZR11lNp7vEcRbZ8w/iRpo	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P39724	uniprotkb:Q15437	intact:EBI-2343154|uniprotkb:D6VPH0|ensemblfungi:YAL046C	intact:EBI-742673|uniprotkb:Q5W183|uniprotkb:Q9BS15|uniprotkb:Q9BSI2|uniprotkb:Q9H1D7|intact:EBI-1048165|uniprotkb:Q503A9|uniprotkb:D3DW33|ensembl:ENSP00000262544|ensembl:ENSP00000338844|ensembl:ENSP00000366685|ensembl:ENSP00000497473	psi-mi:bol3_yeast(display_long)|uniprotkb:BOL3(gene name)|psi-mi:BOL3(display_short)|uniprotkb:AIM1(gene name synonym)|uniprotkb:Altered inheritance of mitochondria protein 1(gene name synonym)|uniprotkb:YAL046C(locus name)	psi-mi:sc23b_human(display_long)|uniprotkb:SEC23-related protein B(gene name synonym)|uniprotkb:SEC23B(gene name)|psi-mi:SEC23B(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11559262|imex:IM-24995-4817	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009353.1|sgd:S000000044|interpro:IPR002634(BolA-like protein)|interpro:IPR036065|mint:P39724|ensemblfungi:YAL046C(gene)|ensemblfungi:YAL046C_mRNA(transcript)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0106035"(protein maturation by [4Fe-4S] cluster transfer)|sgd:YAL046C(identity)	refseq:NP_001166216.1|refseq:NP_006354.2|refseq:NP_116780.1|refseq:NP_116781.1|ensembl:ENSG00000101310(gene)|ensembl:ENST00000262544(transcript)|ensembl:ENST00000336714(transcript)|ensembl:ENST00000377465(transcript)|ensembl:ENST00000650089(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008270"(zinc ion binding)|go:"GO:0012505"(endomembrane system)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0090110"(COPII-coated vesicle cargo loading)|go:"GO:0070971"(endoplasmic reticulum exit site)|interpro:IPR006895(Zinc finger, Sec23/Sec24-type)|interpro:IPR006896(Sec23/Sec24 trunk region)|interpro:IPR006900(Sec23/Sec24 helical region)|interpro:IPR007123(Gelsolin region)|interpro:IPR012990(Sec23/Sec24 beta-sandwich)|interpro:IPR029006|interpro:IPR036174|interpro:IPR036175|interpro:IPR036180|interpro:IPR036465|interpro:IPR037364|interpro:IPR037550|mint:Q15437|refseq:XP_016883082.1|entrezgene/locuslink:10483(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:MLrW6Iu4YKXf87O1cyx5bY03VdE559292	rogid:+3KZ/1jjziSgJRcr81Axquofkl49606	intact-crc:D390BED6EBB84795|rigid:8MkNnnAeJJBcyFBfag9U5MtleHo	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q13422-7	uniprotkb:P39724	intact:EBI-11522367|ensembl:ENSP00000352123|ensembl:ENSP00000413025	intact:EBI-2343154|uniprotkb:D6VPH0|ensemblfungi:YAL046C	psi-mi:q13422-7(display_long)|uniprotkb:IKZF1(gene name)|psi-mi:IKZF1(display_short)|uniprotkb:IK1(gene name synonym)|uniprotkb:IKAROS(gene name synonym)|uniprotkb:Ikaros family zinc finger protein 1(gene name synonym)|uniprotkb:LYF1(gene name synonym)|uniprotkb:Lymphoid transcription factor LyF-1(gene name synonym)|uniprotkb:ZNFN1A1(gene name synonym)	psi-mi:bol3_yeast(display_long)|uniprotkb:BOL3(gene name)|psi-mi:BOL3(display_short)|uniprotkb:AIM1(gene name synonym)|uniprotkb:Altered inheritance of mitochondria protein 1(gene name synonym)|uniprotkb:YAL046C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11559253|imex:IM-24995-4816	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-745305(isoform-parent)|ensembl:ENSG00000185811(gene)|ensembl:ENST00000359197(transcript)|ensembl:ENST00000439701(transcript)|uniprotkb:Q13422-7(isoform-parent)|entrezgene/locuslink:10320(identity)	refseq:NP_009353.1|sgd:S000000044|interpro:IPR002634(BolA-like protein)|interpro:IPR036065|mint:P39724|ensemblfungi:YAL046C(gene)|ensemblfungi:YAL046C_mRNA(transcript)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0106035"(protein maturation by [4Fe-4S] cluster transfer)|sgd:YAL046C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:ou/ovXYoMneBNVp4pj38VxenfyY9606	rogid:MLrW6Iu4YKXf87O1cyx5bY03VdE559292	intact-crc:A470F850119F4AC6|rigid:lFaKlyvgqMNhBmdwnTwouFOxKOM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P39724	uniprotkb:O76003	intact:EBI-2343154|uniprotkb:D6VPH0|ensemblfungi:YAL046C	intact:EBI-374781|uniprotkb:Q96CE0|uniprotkb:Q9P1B0|uniprotkb:Q9P1B1|uniprotkb:B3KMP7|uniprotkb:B3KMQ5|uniprotkb:Q5JV01|ensembl:ENSP00000330836|ensembl:ENSP00000357633|ensembl:ENSP00000435445|uniprotkb:D3DRG2	psi-mi:bol3_yeast(display_long)|uniprotkb:BOL3(gene name)|psi-mi:BOL3(display_short)|uniprotkb:AIM1(gene name synonym)|uniprotkb:Altered inheritance of mitochondria protein 1(gene name synonym)|uniprotkb:YAL046C(locus name)	psi-mi:glrx3_human(display_long)|uniprotkb:GLRX3(gene name)|psi-mi:GLRX3(display_short)|uniprotkb:Thioredoxin-like protein 2(gene name synonym)|uniprotkb:PKC-interacting cousin of thioredoxin(gene name synonym)|uniprotkb:PKC-theta-interacting protein(gene name synonym)|uniprotkb:PICOT(gene name synonym)|uniprotkb:HUSSY-22(orf name)|uniprotkb:TXNL2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11559244|imex:IM-24995-4815	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009353.1|sgd:S000000044|interpro:IPR002634(BolA-like protein)|interpro:IPR036065|mint:P39724|ensemblfungi:YAL046C(gene)|ensemblfungi:YAL046C_mRNA(transcript)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0106035"(protein maturation by [4Fe-4S] cluster transfer)|sgd:YAL046C(identity)	ensembl:ENSG00000108010(gene)|ensembl:ENST00000331244(transcript)|ensembl:ENST00000368644(transcript)|ensembl:ENST00000481034(transcript)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0003723"(RNA binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0030018"(Z disc)|go:"GO:0030425"(dendrite)|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051536"(iron-sulfur cluster binding)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|go:"GO:0097573"(glutathione oxidoreductase activity)|interpro:IPR002109(Glutaredoxin)|interpro:IPR004480(Glutaredoxin-related protein)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR033658|interpro:IPR036249|mint:O76003|rcsb pdb:2DIY|rcsb pdb:2WZ9|rcsb pdb:2YAN|rcsb pdb:3ZYW|reactome:R-HSA-917937|refseq:NP_001186797.1|refseq:NP_006532.2|dip:DIP-31306N|entrezgene/locuslink:10539(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:MLrW6Iu4YKXf87O1cyx5bY03VdE559292	rogid:iKUSt6zbNzzXSKvW+vXMq3hKsEM9606	intact-crc:85D41259B3C80A95|rigid:65CXs8AEkDwCIAvSRuAP0q6t2ck	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P39682	uniprotkb:Q9Y2W2	intact:EBI-612|uniprotkb:D6VZC9|uniprotkb:E9P8Z1|ensemblfungi:YML046W	intact:EBI-714455|ensembl:ENSP00000261167|uniprotkb:Q96AY8	psi-mi:prp39_yeast(display_long)|uniprotkb:YM9827.06(orf name)|uniprotkb:YML046W(locus name)|uniprotkb:PRP39(gene name)|psi-mi:PRP39(display_short)	psi-mi:wbp11_human(display_long)|uniprotkb:SH3 domain-binding protein SNP70(gene name synonym)|uniprotkb:Npw38-binding protein(gene name synonym)|uniprotkb:WBP11(gene name)|psi-mi:WBP11(display_short)|uniprotkb:NPWBP(gene name synonym)|uniprotkb:SNP70(gene name synonym)|uniprotkb:SIPP1(gene name synonym)|uniprotkb:Splicing factor that interacts with PQBP-1 and PP1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11559235|imex:IM-24995-4814	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013667.1|sgd:S000004509|dip:DIP-812N|mint:P39682|ensemblfungi:YML046W(gene)|ensemblfungi:YML046W_mRNA(transcript)|go:"GO:0000243"(commitment complex)|go:"GO:0000395"(mRNA 5'-splice site recognition)|go:"GO:0005685"(U1 snRNP)|go:"GO:0071004"(U2-type prespliceosome)|interpro:IPR003107(RNA-processing protein, HAT helix)|interpro:IPR011990(Tetratricopeptide-like helical)|rcsb pdb:5ZWN|rcsb pdb:6G90|rcsb pdb:6N7P|rcsb pdb:6N7R|rcsb pdb:6N7X|sgd:YML046W(identity)	rcsb pdb:7ABG|reactome:R-HSA-72163|ensembl:ENSG00000084463(gene)|ensembl:ENST00000261167(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045292"(mRNA cis splicing, via spliceosome)|go:"GO:0050699"(WW domain binding)|interpro:IPR019007|mint:Q9Y2W2|rcsb pdb:7ABF|refseq:NP_057396.1|entrezgene/locuslink:51729(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:urVLzQFKnYT1bYOs3yRd9dd7lMk559292	rogid:qE03bpSsQiJouJbn6ISt8DnD/pA9606	intact-crc:EB767D6E8904B803|rigid:oltImCl3zp8ZWC8W1/c6MUH6kTI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UHX1-6	uniprotkb:P39682	intact:EBI-11085298|ensembl:ENSP00000431960	intact:EBI-612|uniprotkb:D6VZC9|uniprotkb:E9P8Z1|ensemblfungi:YML046W	psi-mi:q9uhx1-6(display_long)|uniprotkb:PUF60(gene name)|psi-mi:PUF60(display_short)|uniprotkb:"60 kDa poly(U)-binding-splicing factor"(gene name synonym)|uniprotkb:FIR(gene name synonym)|uniprotkb:FUSE-binding protein-interacting repressor(gene name synonym)|uniprotkb:ROBPI(gene name synonym)|uniprotkb:Ro-binding protein 1(gene name synonym)|uniprotkb:SIAHBP1(gene name synonym)|uniprotkb:Siah-binding protein 1(gene name synonym)	psi-mi:prp39_yeast(display_long)|uniprotkb:YM9827.06(orf name)|uniprotkb:YML046W(locus name)|uniprotkb:PRP39(gene name)|psi-mi:PRP39(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11559224|imex:IM-24995-4813	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000179950(gene)|ensembl:ENST00000527197(transcript)|intact:EBI-1053259(isoform-parent)|uniprotkb:Q9UHX1-6(isoform-parent)|entrezgene/locuslink:22827(identity)	refseq:NP_013667.1|sgd:S000004509|dip:DIP-812N|mint:P39682|ensemblfungi:YML046W(gene)|ensemblfungi:YML046W_mRNA(transcript)|go:"GO:0000243"(commitment complex)|go:"GO:0000395"(mRNA 5'-splice site recognition)|go:"GO:0005685"(U1 snRNP)|go:"GO:0071004"(U2-type prespliceosome)|interpro:IPR003107(RNA-processing protein, HAT helix)|interpro:IPR011990(Tetratricopeptide-like helical)|rcsb pdb:5ZWN|rcsb pdb:6G90|rcsb pdb:6N7P|rcsb pdb:6N7R|rcsb pdb:6N7X|sgd:YML046W(identity)	-	isoform-comment:"Contains a glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) at position 14."	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:rSsTImwmpEAWMCxLzF5Y4zVdeFM9606	rogid:urVLzQFKnYT1bYOs3yRd9dd7lMk559292	intact-crc:8DFF85C9E9E8B473|rigid:h06io8tHQ7CJ44GBbEpCK/JxMjc	false	sufficient binding region:15-513	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q08379	uniprotkb:P39729	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	intact:EBI-20651|uniprotkb:D6VPI1|ensemblfungi:YAL036C	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:rbg1_yeast(display_long)|uniprotkb:GTP-binding protein RBG1(gene name synonym)|uniprotkb:YAL036C(locus name)|uniprotkb:RBG1(gene name)|psi-mi:RBG1(display_short)|uniprotkb:FUN11(gene name synonym)|uniprotkb:Genetically interacts with ribosomal genes protein 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11559298|imex:IM-24995-4821	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N|entrezgene/locuslink:2801(identity)	refseq:NP_009364.1|sgd:S000000034|ensemblfungi:YAL036C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005844"(polysome)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:1903833"(positive regulation of cellular response to amino acid starvation)|interpro:IPR004095(TGS)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006073(GTP1/OBG)|interpro:IPR006074(GTP1/OBG, conserved site)|interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|interpro:IPR012676(TGS-like)|interpro:IPR027417|interpro:IPR031167|interpro:IPR031662|rcsb pdb:4A9A|ensemblfungi:YAL036C(gene)|dip:DIP-1750N|mint:P39729|sgd:YAL036C(identity)	-	-	crc64:D25C6C732B462A6B	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2017/05/26	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	rogid:PYUgCeuX5pWutVTDI01InMby/OE559292	intact-crc:E07BD141AD3681A2|rigid:NPLA9nGy9IG1IB+lxlh4nLZNLCU	false	sufficient binding region:383-1002	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P39724	uniprotkb:Q8NHQ1	intact:EBI-2343154|uniprotkb:D6VPH0|ensemblfungi:YAL046C	intact:EBI-739624|ensembl:ENSP00000264982|ensembl:ENSP00000419231|uniprotkb:Q96B31|uniprotkb:Q9H2C3|uniprotkb:Q9H2Z1|uniprotkb:Q9H940|uniprotkb:D3DNE9|uniprotkb:B7Z5I8|uniprotkb:B7Z7E8|uniprotkb:F5GZX8	psi-mi:bol3_yeast(display_long)|uniprotkb:BOL3(gene name)|psi-mi:BOL3(display_short)|uniprotkb:AIM1(gene name synonym)|uniprotkb:Altered inheritance of mitochondria protein 1(gene name synonym)|uniprotkb:YAL046C(locus name)	psi-mi:cep70_human(display_long)|uniprotkb:CEP70(gene name)|psi-mi:CEP70(display_short)|uniprotkb:BITE(gene name synonym)|uniprotkb:p10-binding protein(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11559289|imex:IM-24995-4820	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009353.1|sgd:S000000044|interpro:IPR002634(BolA-like protein)|interpro:IPR036065|mint:P39724|ensemblfungi:YAL046C(gene)|ensemblfungi:YAL046C_mRNA(transcript)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0106035"(protein maturation by [4Fe-4S] cluster transfer)|sgd:YAL046C(identity)	ensembl:ENSG00000114107(gene)|ensembl:ENST00000264982(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|interpro:IPR019734|interpro:IPR037692|mint:Q8NHQ1|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|ensembl:ENST00000484888(transcript)|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_077817.2|refseq:XP_016862764.1|refseq:NP_001275893.1|refseq:NP_001275894.1|refseq:NP_001275895.1|refseq:NP_001275896.1|refseq:NP_001307527.1|refseq:NP_001307529.1|entrezgene/locuslink:80321(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:MLrW6Iu4YKXf87O1cyx5bY03VdE559292	rogid:S4yveQWcvdVtAUX65gqrJ5Dv0Mc9606	intact-crc:6680976592953001|rigid:8wdt3l1cquQehSaPTrETtvhqtDw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8N9N5-2	uniprotkb:P39724	intact:EBI-11524452|ensembl:ENSP00000347125	intact:EBI-2343154|uniprotkb:D6VPH0|ensemblfungi:YAL046C	psi-mi:q8n9n5-2(display_long)|uniprotkb:BANP(gene name)|psi-mi:BANP(display_short)|uniprotkb:BEN domain-containing protein 1(gene name synonym)|uniprotkb:BEND1(gene name synonym)|uniprotkb:Btg3-associated nuclear protein(gene name synonym)|uniprotkb:SMAR1(gene name synonym)|uniprotkb:Scaffold/matrix-associated region-1-binding protein(gene name synonym)	psi-mi:bol3_yeast(display_long)|uniprotkb:BOL3(gene name)|psi-mi:BOL3(display_short)|uniprotkb:AIM1(gene name synonym)|uniprotkb:Altered inheritance of mitochondria protein 1(gene name synonym)|uniprotkb:YAL046C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11559280|imex:IM-24995-4819	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000172530(gene)|ensembl:ENST00000355022(transcript)|intact:EBI-744695(isoform-parent)|uniprotkb:Q8N9N5-2(isoform-parent)|entrezgene/locuslink:54971(identity)	refseq:NP_009353.1|sgd:S000000044|interpro:IPR002634(BolA-like protein)|interpro:IPR036065|mint:P39724|ensemblfungi:YAL046C(gene)|ensemblfungi:YAL046C_mRNA(transcript)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0106035"(protein maturation by [4Fe-4S] cluster transfer)|sgd:YAL046C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:ESe6iCAhvq+i57fQHz3rGyg6UOo9606	rogid:MLrW6Iu4YKXf87O1cyx5bY03VdE559292	intact-crc:51020EBC5728305D|rigid:ccEvLtoXDVwSCelr9mseh0wQBAY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P39724	uniprotkb:Q15654	intact:EBI-2343154|uniprotkb:D6VPH0|ensemblfungi:YAL046C	intact:EBI-742327|uniprotkb:O15170|uniprotkb:O15275|uniprotkb:Q9BTB2|uniprotkb:Q9BUE5|uniprotkb:Q9BXP3|uniprotkb:Q9UNT4|uniprotkb:A4D2E7|ensembl:ENSP00000200457|uniprotkb:F2ZC07|uniprotkb:F2ZC08	psi-mi:bol3_yeast(display_long)|uniprotkb:BOL3(gene name)|psi-mi:BOL3(display_short)|uniprotkb:AIM1(gene name synonym)|uniprotkb:Altered inheritance of mitochondria protein 1(gene name synonym)|uniprotkb:YAL046C(locus name)	psi-mi:trip6_human(display_long)|uniprotkb:TRIP6(gene name)|psi-mi:TRIP6(display_short)|uniprotkb:OIP1(gene name synonym)|uniprotkb:Opa-interacting protein 1(gene name synonym)|uniprotkb:Zyxin-related protein 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11559271|imex:IM-24995-4818	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009353.1|sgd:S000000044|interpro:IPR002634(BolA-like protein)|interpro:IPR036065|mint:P39724|ensemblfungi:YAL046C(gene)|ensemblfungi:YAL046C_mRNA(transcript)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0106035"(protein maturation by [4Fe-4S] cluster transfer)|sgd:YAL046C(identity)	refseq:NP_003293.2|ensembl:ENSP00000200457|ensembl:ENST00000417475|ensembl:ENSP00000413817|ensembl:ENST00000437505|ensembl:ENSP00000410736|ensembl:ENST00000619988|ensembl:ENSP00000479865|ensembl:ENSG00000087077(gene)|ensembl:ENST00000200457(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003723"(RNA binding)|go:"GO:0005149"(interleukin-1 receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0019900"(kinase binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0043009"(chordate embryonic development)|go:"GO:0046872"(metal ion binding)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|interpro:IPR001781(Zinc finger, LIM-type)|mint:Q15654|rcsb pdb:1X61|rcsb pdb:2DLO|dip:DIP-34466N|entrezgene/locuslink:7205(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:MLrW6Iu4YKXf87O1cyx5bY03VdE559292	rogid:9Okf3b6sMMwX5awAx991GN9iSsQ9606	intact-crc:395B2812FE6AE3FF|rigid:DQ5th5VfoAYEXx1mb5UxyiScCQI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96HB5	uniprotkb:P39946	intact:EBI-744556|uniprotkb:B4DTU2|ensembl:ENSP00000470294|ensembl:ENSP00000474761|ensembl:ENSP00000475676|uniprotkb:A8K5Q5|uniprotkb:B4DF24|uniprotkb:F5GZU4|uniprotkb:B4DFC1	intact:EBI-12838|uniprotkb:D6W2W9|ensemblfungi:YOR269W	psi-mi:cc120_human(display_long)|uniprotkb:CCDC120(gene name)|psi-mi:CCDC120(display_short)|uniprotkb:JM11(orf name)	psi-mi:lis1_yeast(display_long)|uniprotkb:PAC1(gene name)|psi-mi:PAC1(display_short)|uniprotkb:nudF homolog(gene name synonym)|uniprotkb:LIS1(gene name synonym)|uniprotkb:Lissencephaly-1 homolog(gene name synonym)|uniprotkb:YOR269W(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11559336|imex:IM-24995-4825	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001156795.1|refseq:NP_296375.1|go:"GO:0005814"(centriole)|go:"GO:0008104"(protein localization)|go:"GO:0030426"(growth cone)|go:"GO:0034454"(microtubule anchoring at centrosome)|go:"GO:0120103"(centriolar subdistal appendage)|interpro:IPR021774|interpro:IPR039108|interpro:IPR043447|ensembl:ENSG00000147144(gene)|ensembl:ENST00000496529(transcript)|ensembl:ENST00000597275(transcript)|ensembl:ENST00000606812(transcript)|go:"GO:0005768"(endosome)|refseq:NP_001258764.1|refseq:NP_001258765.1|refseq:NP_001156793.2|refseq:NP_001156794.1|entrezgene/locuslink:90060(identity)	ensemblfungi:YOR269W(gene)|ensemblfungi:YOR269W_mRNA(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007097"(nuclear migration)|go:"GO:0030473"(nuclear migration along microtubule)|go:"GO:0031023"(microtubule organizing center organization)|go:"GO:0042802"(identical protein binding)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0051012"(microtubule sliding)|go:"GO:0051301"(cell division)|go:"GO:0070840"(dynein complex binding)|go:"GO:1903033"(positive regulation of microtubule plus-end binding)|go:"GO:2000574"(obsolete regulation of microtubule motor activity)|go:"GO:2000582"(obsolete positive regulation of microtubule motor activity, plus-end-directed)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR017252(Dynein regulator)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|interpro:IPR037190|rcsb pdb:5VH9|rcsb pdb:5VLJ|refseq:NP_014912.1|sgd:S000005795|mint:P39946|dip:DIP-1485N|sgd:YOR269W(identity)	-	-	crc64:E667E4BA7602FB3B	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:uBgmQJDTqECaTKOU/uQQHkWB/Nc9606	rogid:tyU5fR5V8csklk2QqAQHt3Mmz7c559292	intact-crc:E5E405CEC926E5C9|rigid:uN0faWdTYD57KDUYwnOtCHBY2BE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P39946	uniprotkb:Q5JR59-3	intact:EBI-12838|uniprotkb:D6W2W9|ensemblfungi:YOR269W	intact:EBI-11522433|ensembl:ENSP00000370186	psi-mi:lis1_yeast(display_long)|uniprotkb:PAC1(gene name)|psi-mi:PAC1(display_short)|uniprotkb:nudF homolog(gene name synonym)|uniprotkb:LIS1(gene name synonym)|uniprotkb:Lissencephaly-1 homolog(gene name synonym)|uniprotkb:YOR269W(locus name)	psi-mi:q5jr59-3(display_long)|uniprotkb:MTUS2(gene name)|psi-mi:MTUS2(display_short)|uniprotkb:CAZIP(gene name synonym)|uniprotkb:Cardiac zipper protein(gene name synonym)|uniprotkb:KIAA0774(gene name synonym)|uniprotkb:Microtubule plus-end tracking protein TIP150(gene name synonym)|uniprotkb:TIP150(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11559327|imex:IM-24995-4824	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YOR269W(gene)|ensemblfungi:YOR269W_mRNA(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007097"(nuclear migration)|go:"GO:0030473"(nuclear migration along microtubule)|go:"GO:0031023"(microtubule organizing center organization)|go:"GO:0042802"(identical protein binding)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0051012"(microtubule sliding)|go:"GO:0051301"(cell division)|go:"GO:0070840"(dynein complex binding)|go:"GO:1903033"(positive regulation of microtubule plus-end binding)|go:"GO:2000574"(obsolete regulation of microtubule motor activity)|go:"GO:2000582"(obsolete positive regulation of microtubule motor activity, plus-end-directed)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR017252(Dynein regulator)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|interpro:IPR037190|rcsb pdb:5VH9|rcsb pdb:5VLJ|refseq:NP_014912.1|sgd:S000005795|mint:P39946|dip:DIP-1485N|sgd:YOR269W(identity)	ensembl:ENSG00000132938(gene)|ensembl:ENST00000380808(transcript)|intact:EBI-742948(isoform-parent)|uniprotkb:Q5JR59-3(isoform-parent)|entrezgene/locuslink:23281(identity)	-	crc64:E667E4BA7602FB3B	isoform-comment:No experimental confirmation available.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:tyU5fR5V8csklk2QqAQHt3Mmz7c559292	rogid:npId9tC7VoLN/jteoBiRbSYChPs9606	intact-crc:2EFE29BE09F5F9B5|rigid:mcPqwa1Q/HPtG6yn9wOQcWws6DA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q14566	uniprotkb:P39946	intact:EBI-374900|uniprotkb:Q13504|uniprotkb:Q99859|uniprotkb:B2R6H2|ensembl:ENSP00000264156	intact:EBI-12838|uniprotkb:D6W2W9|ensemblfungi:YOR269W	psi-mi:mcm6_human(display_long)|uniprotkb:MCM6(gene name)|psi-mi:MCM6(display_short)|uniprotkb:p105MCM(gene name synonym)	psi-mi:lis1_yeast(display_long)|uniprotkb:PAC1(gene name)|psi-mi:PAC1(display_short)|uniprotkb:nudF homolog(gene name synonym)|uniprotkb:LIS1(gene name synonym)|uniprotkb:Lissencephaly-1 homolog(gene name synonym)|uniprotkb:YOR269W(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11559318|imex:IM-24995-4823	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000264156(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0042555"(MCM complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902969"(mitotic DNA replication)|ensembl:ENSG00000076003(gene)|reactome:R-HSA-68962|reactome:R-HSA-69052|interpro:IPR008049(MCM protein 6)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041024|interpro:IPR041562|interpro:IPR001208(MCM)|mint:Q14566|rcsb pdb:2KLQ|rcsb pdb:2LE8|rcsb pdb:6XTX|rcsb pdb:6XTY|reactome:R-HSA-176187|reactome:R-HSA-176974|reactome:R-HSA-68867|reactome:R-HSA-68949|refseq:NP_005906.2|dip:DIP-31727N|entrezgene/locuslink:4175(identity)	ensemblfungi:YOR269W(gene)|ensemblfungi:YOR269W_mRNA(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007097"(nuclear migration)|go:"GO:0030473"(nuclear migration along microtubule)|go:"GO:0031023"(microtubule organizing center organization)|go:"GO:0042802"(identical protein binding)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0051012"(microtubule sliding)|go:"GO:0051301"(cell division)|go:"GO:0070840"(dynein complex binding)|go:"GO:1903033"(positive regulation of microtubule plus-end binding)|go:"GO:2000574"(obsolete regulation of microtubule motor activity)|go:"GO:2000582"(obsolete positive regulation of microtubule motor activity, plus-end-directed)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR017252(Dynein regulator)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|interpro:IPR037190|rcsb pdb:5VH9|rcsb pdb:5VLJ|refseq:NP_014912.1|sgd:S000005795|mint:P39946|dip:DIP-1485N|sgd:YOR269W(identity)	-	-	crc64:E667E4BA7602FB3B	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:gVpEwgfSwwxvP2T2CvCzIukthY49606	rogid:tyU5fR5V8csklk2QqAQHt3Mmz7c559292	intact-crc:41589A462B6F741F|rigid:ph2S3f8CdLJnhy9N1oGHGPx3SBc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P39729	uniprotkb:Q9UKT9	intact:EBI-20651|uniprotkb:D6VPI1|ensemblfungi:YAL036C	intact:EBI-747204|uniprotkb:Q8WWQ9|uniprotkb:Q8WWR0|uniprotkb:Q8WWR1|uniprotkb:Q8WWR2|uniprotkb:Q8WWR3|uniprotkb:Q8N574|uniprotkb:B4DVV5|uniprotkb:Q69BL6|uniprotkb:Q69BL7|uniprotkb:Q69BL8|uniprotkb:Q69BL9|uniprotkb:Q69BM0|uniprotkb:Q69BM1|uniprotkb:Q69BM2|uniprotkb:Q69BM3|uniprotkb:Q69BM5|ensembl:ENSP00000344544	psi-mi:rbg1_yeast(display_long)|uniprotkb:GTP-binding protein RBG1(gene name synonym)|uniprotkb:YAL036C(locus name)|uniprotkb:RBG1(gene name)|psi-mi:RBG1(display_short)|uniprotkb:FUN11(gene name synonym)|uniprotkb:Genetically interacts with ribosomal genes protein 1(gene name synonym)	psi-mi:ikzf3_human(display_long)|uniprotkb:ZNFN1A3(gene name synonym)|uniprotkb:Ikaros family zinc finger protein 3(gene name synonym)|uniprotkb:IKZF3(gene name)|psi-mi:IKZF3(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11559309|imex:IM-24995-4822	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009364.1|sgd:S000000034|ensemblfungi:YAL036C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005844"(polysome)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:1903833"(positive regulation of cellular response to amino acid starvation)|interpro:IPR004095(TGS)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006073(GTP1/OBG)|interpro:IPR006074(GTP1/OBG, conserved site)|interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|interpro:IPR012676(TGS-like)|interpro:IPR027417|interpro:IPR031167|interpro:IPR031662|rcsb pdb:4A9A|ensemblfungi:YAL036C(gene)|dip:DIP-1750N|mint:P39729|sgd:YAL036C(identity)	refseq:NP_001271443.1|refseq:NP_001271444.1|refseq:NP_036613.2|refseq:NP_899051.1|refseq:NP_899052.1|refseq:NP_899053.1|refseq:NP_899054.1|refseq:NP_899055.1|refseq:NP_001271445.1|refseq:NP_001244337.1|refseq:NP_001244338.1|refseq:NP_001244339.1|refseq:NP_001244340.1|refseq:NP_001244341.1|refseq:NP_001244342.1|refseq:NP_001244343.1|ensembl:ENSG00000161405(gene)|ensembl:ENST00000346872(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007498"(mesoderm development)|go:"GO:0009617"(response to bacterium)|go:"GO:0030888"(regulation of B cell proliferation)|go:"GO:0042113"(B cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045577"(regulation of B cell differentiation)|go:"GO:0045619"(regulation of lymphocyte differentiation)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|go:"GO:0046872"(metal ion binding)|dip:DIP-56975N|entrezgene/locuslink:22806(identity)	-	crc64:D25C6C732B462A6B	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:PYUgCeuX5pWutVTDI01InMby/OE559292	rogid:2Kp6LefSLfK5VIiE6DmQusFIfMY9606	intact-crc:93C0C69A4F091D98|rigid:Sa2J/1L1/w2ba1KoabuxlTAyzQE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P39962	uniprotkb:P50222	intact:EBI-4740|uniprotkb:D3DM29|ensemblfungi:YER123W	intact:EBI-748397|uniprotkb:O75263|ensembl:ENSP00000262041|uniprotkb:Q9UPL6|uniprotkb:B2R8I7|intact:EBI-10172134|intact:EBI-11522964|intact:EBI-11750003|intact:EBI-12702266|uniprotkb:A4D127	psi-mi:kc13_yeast(display_long)|uniprotkb:YCK3(gene name)|psi-mi:YCK3(display_short)|uniprotkb:CKI3(gene name synonym)|uniprotkb:YER123W(locus name)	psi-mi:meox2_human(display_long)|uniprotkb:Mesenchyme homeobox 2(gene name synonym)|uniprotkb:Growth arrest-specific homeobox(gene name synonym)|uniprotkb:MEOX2(gene name)|psi-mi:MEOX2(display_short)|uniprotkb:GAX(gene name synonym)|uniprotkb:MOX2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11559365|imex:IM-24995-4828	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011049.2|sgd:S000000925|dip:DIP-6331N|mint:P39962|ensemblfungi:YER123W(gene)|ensemblfungi:YER123W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006897"(endocytosis)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0031965"(nuclear membrane)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|sgd:YER123W(identity)	ensembl:ENSG00000106511(gene)|ensembl:ENST00000262041(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0001757"(somite specification)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007275"(multicellular organism development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008015"(blood circulation)|go:"GO:0016607"(nuclear speck)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060173"(limb development)|go:"GO:0061053"(somite development)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR042634|refseq:NP_005915.2|entrezgene/locuslink:4223(identity)	-	crc64:FD4BBA311D0CD805	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2017/05/26	rogid:RIRZO4asqxXqkm1L6tHZtWI/rQQ559292	rogid:fMv0ruKikzQ3MC0PBvJ3pOAjW+U9606	intact-crc:502BF2F82E028034|rigid:cwsTXbnKusLLEFlzzX/sy7fgHR4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P39961	uniprotkb:Q9H9H4	intact:EBI-22239|uniprotkb:D3DM93|ensemblfungi:YER184C	intact:EBI-4400866|intact:EBI-28975719|ensembl:ENSP00000267202	psi-mi:tog1_yeast(display_long)|uniprotkb:TOG1(gene name)|psi-mi:TOG1(display_short)|uniprotkb:Transcriptional regulator of oleate 1(gene name synonym)|uniprotkb:YER184C(locus name)	psi-mi:vp37b_human(display_long)|uniprotkb:VPS37B(gene name)|psi-mi:VPS37B(display_short)|uniprotkb:ESCRT-I complex subunit VPS37B(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11559356|imex:IM-24995-4827	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011111.1|sgd:S000000986|dip:DIP-5488N|mint:P39961|ensemblfungi:YER184C(gene)|ensemblfungi:YER184C_mRNA(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR001138(Fungal transcriptional regulatory protein, N-terminal)|interpro:IPR007219(Fungal specific transcription factor)|interpro:IPR036864|sgd:YER184C(identity)	ensembl:ENSP00000267202|refseq:NP_078943.1|ensembl:ENSG00000139722(gene)|ensembl:ENST00000267202(transcript)|go:"GO:0000813"(ESCRT I complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0010008"(endosome membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0030496"(midbody)|go:"GO:0031902"(late endosome membrane)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1902188"(obsolete positive regulation of viral release from host cell)|go:"GO:1903774"(positive regulation of viral budding via host ESCRT complex)|interpro:IPR009851(Modifier of rudimentary, Modr)|interpro:IPR029012|interpro:IPR037202|mint:Q9H9H4|rcsb pdb:6VME|reactome:R-HSA-162588|reactome:R-HSA-174490|reactome:R-HSA-917729|reactome:R-HSA-9610379|reactome:R-HSA-9615710|entrezgene/locuslink:79720(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:5LvJUSL4Do4rBxPon6hQplqYXFU559292	rogid:dj398+zsegXf+gk9OiSeZAVlmqk9606	intact-crc:0C0CAE650D279058|rigid:T3u93KxnR1U6au4MV/V3opPIwjE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P39946	uniprotkb:Q9UJV3-2	intact:EBI-12838|uniprotkb:D6W2W9|ensemblfungi:YOR269W	intact:EBI-10172526|ensembl:ENSP00000413976	psi-mi:lis1_yeast(display_long)|uniprotkb:PAC1(gene name)|psi-mi:PAC1(display_short)|uniprotkb:nudF homolog(gene name synonym)|uniprotkb:LIS1(gene name synonym)|uniprotkb:Lissencephaly-1 homolog(gene name synonym)|uniprotkb:YOR269W(locus name)	psi-mi:q9ujv3-2(display_long)|uniprotkb:RING-type E3 ubiquitin transferase MID2(gene name synonym)|uniprotkb:FXY2(gene name synonym)|uniprotkb:Midin-2(gene name synonym)|uniprotkb:Midline defect 2(gene name synonym)|uniprotkb:Midline-2(gene name synonym)|uniprotkb:RING finger protein 60(gene name synonym)|uniprotkb:RNF60(gene name synonym)|uniprotkb:TRIM1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 1(gene name synonym)|uniprotkb:MID2(gene name)|psi-mi:MID2(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11559345|imex:IM-24995-4826	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YOR269W(gene)|ensemblfungi:YOR269W_mRNA(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007097"(nuclear migration)|go:"GO:0030473"(nuclear migration along microtubule)|go:"GO:0031023"(microtubule organizing center organization)|go:"GO:0042802"(identical protein binding)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0051012"(microtubule sliding)|go:"GO:0051301"(cell division)|go:"GO:0070840"(dynein complex binding)|go:"GO:1903033"(positive regulation of microtubule plus-end binding)|go:"GO:2000574"(obsolete regulation of microtubule motor activity)|go:"GO:2000582"(obsolete positive regulation of microtubule motor activity, plus-end-directed)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR017252(Dynein regulator)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|interpro:IPR037190|rcsb pdb:5VH9|rcsb pdb:5VLJ|refseq:NP_014912.1|sgd:S000005795|mint:P39946|dip:DIP-1485N|sgd:YOR269W(identity)	intact:EBI-751983(isoform-parent)|uniprotkb:Q9UJV3-2(isoform-parent)|ensembl:ENSG00000080561(gene)|ensembl:ENST00000443968(transcript)|entrezgene/locuslink:11043(identity)	-	crc64:E667E4BA7602FB3B	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:tyU5fR5V8csklk2QqAQHt3Mmz7c559292	rogid:/FJ+V2H7SaWon7caUWkEkmHFVxQ9606	intact-crc:15BFE89A8BC0CFC7|rigid:ARbzysojGHvgGNGr1TPCQwd7Vfc	false	-	sufficient binding region:21-705	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q16637-3	uniprotkb:P39990	intact:EBI-395447|ensembl:ENSP00000424926|ensembl:ENSP00000486152|ensembl:ENSP00000487015|ensembl:ENSP00000487029|intact:EBI-8628183|intact:MINT-95595	intact:EBI-12032|ensemblfungi:YEL026W|uniprotkb:D3DLM2	psi-mi:q16637-3(display_long)|uniprotkb:Iso7-SMN(isoform synonym)|uniprotkb:SMN1(gene name)|psi-mi:SMN1(display_short)|uniprotkb:SMN2(gene name)|psi-mi:SMN2(display_short)|uniprotkb:SMN(gene name synonym)|uniprotkb:SMNT(gene name synonym)|uniprotkb:SMNC(gene name synonym)|uniprotkb:Component of gems 1(gene name synonym)|uniprotkb:Gemin-1(gene name synonym)	psi-mi:snu13_yeast(display_long)|uniprotkb:YEL026W(locus name)|uniprotkb:SNU13(gene name)|psi-mi:SNU13(display_short)|uniprotkb:Small nuclear ribonucleoprotein-associated protein 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11559401|imex:IM-24995-4832	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-395421(smn_human)|ensembl:ENSG00000275349(gene)|ensembl:ENST00000506163(transcript)|ensembl:ENST00000626847(transcript)|ensembl:ENST00000628353(transcript)|ensembl:ENST00000628642(transcript)|ensembl:ENSG00000172062(gene)|ensembl:ENSG00000205571(gene)|ensembl:ENSG00000273772(gene)|uniprotkb:Q16637-3(isoform-parent)|entrezgene/locuslink:6607(identity)	ensemblfungi:YEL026W(gene)|ensemblfungi:YEL026W_mRNA(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0030490"(maturation of SSU-rRNA)|go:"GO:0030621"(U4 snRNA binding)|go:"GO:0031428"(box C/D RNP complex)|go:"GO:0032040"(small-subunit processome)|go:"GO:0034511"(U3 snoRNA binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:1905216"(positive regulation of RNA binding)|interpro:IPR002415(High mobility group-like nuclear protein)|interpro:IPR004037(Ribosomal protein L7Ae)|interpro:IPR004038(Ribosomal protein L7Ae/L30e/S12e/Gadd45)|interpro:IPR018492|interpro:IPR029064|rcsb pdb:1ZWZ|rcsb pdb:2ALE|rcsb pdb:3JCM|go:"GO:0005654"(nucleoplasm)|rcsb pdb:5GAN|rcsb pdb:5GAP|rcsb pdb:5NRL|rcsb pdb:5TZS|rcsb pdb:5WLC|rcsb pdb:5WYJ|rcsb pdb:5WYK|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:6KE6|rcsb pdb:6LQP|rcsb pdb:6LQQ|rcsb pdb:6LQR|rcsb pdb:6LQS|rcsb pdb:6LQT|rcsb pdb:6LQU|rcsb pdb:6LQV|rcsb pdb:6ND4|rcsb pdb:6ZQA|rcsb pdb:6ZQB|rcsb pdb:6ZQC|rcsb pdb:6ZQD|rcsb pdb:6ZQE|rcsb pdb:7AJT|rcsb pdb:7AJU|rcsb pdb:4NUT|reactome:R-SCE-6791226|refseq:NP_010888.1|sgd:S000000752|mint:P39990|dip:DIP-2870N|sgd:YEL026W(identity)	-	isoform-comment:Thought to be a non-functional protein that lacks the capacity to oligomerize and thus cannot interact with Sm proteins. Primarily derived from SMN2 gene.	crc64:4489780153E8F182	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:ICA63eidVxJ219M+YZJ20zNh+xU9606	rogid:4C07wkvZ4Nts4Oxw4/L7QMkwcmE559292	intact-crc:61B3D4290405DA00|rigid:gHrDiO7IspHzzgYrGnScU0x9cyM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q16637	uniprotkb:P39990	intact:EBI-395421|uniprotkb:Q13119|uniprotkb:Q549U5|uniprotkb:Q96J51|ensembl:ENSP00000305857|uniprotkb:A8K0V4|ensembl:ENSP00000370083|ensembl:ENSP00000370117|ensembl:ENSP00000370119|ensembl:ENSP00000479920|ensembl:ENSP00000482966|ensembl:ENSP00000483515|ensembl:ENSP00000483819|ensembl:ENSP00000487206|ensembl:ENSP00000487421	intact:EBI-12032|ensemblfungi:YEL026W|uniprotkb:D3DLM2	psi-mi:smn_human(display_long)|uniprotkb:SMN1(gene name)|psi-mi:SMN1(display_short)|uniprotkb:SMN(gene name synonym)|uniprotkb:SMNT(gene name synonym)|uniprotkb:SMN2(gene name)|psi-mi:SMN2(display_short)|uniprotkb:SMNC(gene name synonym)|uniprotkb:Component of gems 1(gene name synonym)|uniprotkb:Gemin-1(gene name synonym)	psi-mi:snu13_yeast(display_long)|uniprotkb:YEL026W(locus name)|uniprotkb:SNU13(gene name)|psi-mi:SNU13(display_short)|uniprotkb:Small nuclear ribonucleoprotein-associated protein 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11559392|imex:IM-24995-4831	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000335.1|refseq:NP_059107.1|refseq:NP_075012.1|refseq:NP_075013.1|refseq:NP_075014.1|refseq:NP_075015.1|ensembl:ENSG00000172062(gene)|ensembl:ENSG00000205571(gene)|ensembl:ENSG00000273772(gene)|ensembl:ENSG00000275349(gene)|ensembl:ENSG00000277773(gene)|ensembl:ENST00000351205(transcript)|ensembl:ENST00000380707(transcript)|ensembl:ENST00000380741(transcript)|ensembl:ENST00000380743(transcript)|ensembl:ENST00000614610(transcript)|ensembl:ENST00000618251(transcript)|ensembl:ENST00000618661(transcript)|ensembl:ENST00000622739(transcript)|ensembl:ENST00000627341(transcript)|ensembl:ENST00000629122(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0007399"(nervous system development)|go:"GO:0015030"(Cajal body)|go:"GO:0016604"(nuclear body)|go:"GO:0030018"(Z disc)|go:"GO:0030424"(axon)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043204"(perikaryon)|go:"GO:0097504"(Gemini of coiled bodies)|interpro:IPR002999(Tudor)|interpro:IPR010304(Survival motor neuron)|mint:Q16637|rcsb pdb:1G5V|rcsb pdb:1MHN|rcsb pdb:2LEH|rcsb pdb:4A4E|rcsb pdb:4A4G|rcsb pdb:4GLI|rcsb pdb:4QQ6|rcsb pdb:5XJL|go:"GO:0034719"(SMN-Sm protein complex)|rcsb pdb:5XJQ|rcsb pdb:5XJR|rcsb pdb:5XJS|rcsb pdb:5XJT|rcsb pdb:5XJU|reactome:R-HSA-191859|go:"GO:0032797"(SMN complex)|refseq:NP_001284644.1|ensembl:ENSP00000305857|ensembl:ENSP00000370083|ensembl:ENSP00000370117|ensembl:ENST00000380742|ensembl:ENSP00000370118|ensembl:ENSP00000370119|ensembl:ENST00000503079|ensembl:ENSP00000428128|ensembl:ENST00000506163|ensembl:ENSP00000424926|ensembl:ENST00000611442|ensembl:ENSP00000483768|ensembl:ENST00000614240|ensembl:ENSP00000479279|ensembl:ENSP00000479920|ensembl:ENST00000614773|ensembl:ENSP00000481427|ensembl:ENSP00000483515|ensembl:ENSP00000483819|ensembl:ENST00000622158|ensembl:ENSP00000480906|ensembl:ENSP00000482966|ensembl:ENST00000624634|ensembl:ENSP00000485595|ensembl:ENST00000626847|ensembl:ENSP00000486152|ensembl:ENSP00000487421|ensembl:ENST00000628353|ensembl:ENSP00000487029|ensembl:ENST00000628642|ensembl:ENSP00000487015|ensembl:ENSP00000487206|refseq:XP_016865275.1|dip:DIP-31309N|entrezgene/locuslink:6607(identity)	ensemblfungi:YEL026W(gene)|ensemblfungi:YEL026W_mRNA(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0030490"(maturation of SSU-rRNA)|go:"GO:0030621"(U4 snRNA binding)|go:"GO:0031428"(box C/D RNP complex)|go:"GO:0032040"(small-subunit processome)|go:"GO:0034511"(U3 snoRNA binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:1905216"(positive regulation of RNA binding)|interpro:IPR002415(High mobility group-like nuclear protein)|interpro:IPR004037(Ribosomal protein L7Ae)|interpro:IPR004038(Ribosomal protein L7Ae/L30e/S12e/Gadd45)|interpro:IPR018492|interpro:IPR029064|rcsb pdb:1ZWZ|rcsb pdb:2ALE|rcsb pdb:3JCM|go:"GO:0005654"(nucleoplasm)|rcsb pdb:5GAN|rcsb pdb:5GAP|rcsb pdb:5NRL|rcsb pdb:5TZS|rcsb pdb:5WLC|rcsb pdb:5WYJ|rcsb pdb:5WYK|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:6KE6|rcsb pdb:6LQP|rcsb pdb:6LQQ|rcsb pdb:6LQR|rcsb pdb:6LQS|rcsb pdb:6LQT|rcsb pdb:6LQU|rcsb pdb:6LQV|rcsb pdb:6ND4|rcsb pdb:6ZQA|rcsb pdb:6ZQB|rcsb pdb:6ZQC|rcsb pdb:6ZQD|rcsb pdb:6ZQE|rcsb pdb:7AJT|rcsb pdb:7AJU|rcsb pdb:4NUT|reactome:R-SCE-6791226|refseq:NP_010888.1|sgd:S000000752|mint:P39990|dip:DIP-2870N|sgd:YEL026W(identity)	-	-	crc64:4489780153E8F182	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:QGivm7E8suciCWXO4l0zCUzCl2g9606	rogid:4C07wkvZ4Nts4Oxw4/L7QMkwcmE559292	intact-crc:486E79B46F6AF5F5|rigid:1WMvd1mwKFzwChd4wkZR1F0aP18	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9Y6D9	uniprotkb:P39976	intact:EBI-742610|uniprotkb:B3KR41|uniprotkb:Q9UNH0|uniprotkb:Q13312|uniprotkb:Q75MI0|uniprotkb:Q86UM4|ensembl:ENSP00000265854|ensembl:ENSP00000382562|ensembl:ENSP00000385334	intact:EBI-5933|uniprotkb:D3DLI0|ensemblfungi:YEL071W	psi-mi:md1l1_human(display_long)|uniprotkb:Mitotic arrest deficient 1-like protein 1(gene name synonym)|uniprotkb:Mitotic checkpoint MAD1 protein homolog(gene name synonym)|uniprotkb:Tax-binding protein 181(gene name synonym)|uniprotkb:MAD1L1(gene name)|psi-mi:MAD1L1(display_short)|uniprotkb:MAD1(gene name synonym)|uniprotkb:TXBP181(gene name synonym)	psi-mi:dld3_yeast(display_long)|uniprotkb:YEL071W(locus name)|uniprotkb:DLD3(gene name)|psi-mi:DLD3(display_short)|uniprotkb:D-lactate ferricytochrome C oxidoreductase(gene name synonym)|uniprotkb:"(R)-2-hydroxyglutarate--pyruvate transhydrogenase"(gene name synonym)|uniprotkb:D-lactate dehydrogenase [cytochrome] 3(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11559374|imex:IM-24995-4829	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001013858.1|refseq:NP_001013859.1|refseq:NP_003541.2|refseq:NP_001291452.1|refseq:NP_001291453.1|ensembl:ENSG00000002822(gene)|ensembl:ENST00000265854(transcript)|go:"GO:0090235"(regulation of metaphase plate congression)|go:"GO:1902426"(deactivation of mitotic spindle assembly checkpoint)|interpro:IPR008672(Mitotic checkpoint)|mint:Q9Y6D9|rcsb pdb:1GO4|rcsb pdb:4DZO|rcsb pdb:7B1F|rcsb pdb:7B1H|rcsb pdb:7B1J|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|ensembl:ENST00000399654(transcript)|ensembl:ENST00000406869(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043515"(kinetochore binding)|go:"GO:0044615"(nuclear pore nuclear basket)|go:"GO:0048538"(thymus development)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0072686"(mitotic spindle)|refseq:XP_005249934.1|dip:DIP-29654N|entrezgene/locuslink:8379(identity)	refseq:NP_010843.1|sgd:S000000797|dip:DIP-6418N|mint:P39976|ensemblfungi:YEL071W(gene)|ensemblfungi:YEL071W_mRNA(transcript)|go:"GO:0004458"("D-lactate dehydrogenase (cytochrome) activity")|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0019249"(lactate biosynthetic process)|go:"GO:0030447"(filamentous growth)|go:"GO:0071949"(FAD binding)|go:"GO:0099615"("(D)-2-hydroxyglutarate-pyruvate transhydrogenase activity")|interpro:IPR004113(FAD-linked oxidase, C-terminal)|interpro:IPR006094(FAD linked oxidase, N-terminal)|interpro:IPR016164(FAD-linked oxidase-like, C-terminal)|interpro:IPR016166(FAD-binding, type 2)|interpro:IPR016167(FAD-binding, type 2, subdomain 1)|interpro:IPR016169(CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2)|interpro:IPR016171(Vanillyl-alcohol oxidase, C-terminal subdomain 2)|interpro:IPR036318|sgd:YEL071W(identity)	-	-	crc64:4809F74EDF07F520	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:9CcqpZlN0IgqC939rIo7vNgOvLQ9606	rogid:f0zrUtFfKHDu2gUN7thcyPp/Z50559292	intact-crc:CB5BBE029059D944|rigid:T24bmbHLm6aNwasOX9GG0Wfbgy0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P39984	uniprotkb:P49910	intact:EBI-8185|uniprotkb:D3DLJ4|ensemblfungi:YEL056W	intact:EBI-741694|intact:EBI-28968591|ensembl:ENSP00000366542|ensembl:ENSP00000507525	psi-mi:hat2_yeast(display_long)|uniprotkb:HAT2(gene name)|psi-mi:HAT2(display_short)|uniprotkb:YEL056W(locus name)	psi-mi:zn165_human(display_long)|uniprotkb:LD65(gene name synonym)|uniprotkb:Zinc finger and SCAN domain-containing protein 7(gene name synonym)|uniprotkb:Cancer/testis antigen 53(gene name synonym)|uniprotkb:ZNF165(gene name)|psi-mi:ZNF165(display_short)|uniprotkb:ZPF165(gene name synonym)|uniprotkb:ZSCAN7(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11559383|imex:IM-24995-4830	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000000782|refseq:NP_010858.3|mint:P39984|dip:DIP-2363N|ensemblfungi:YEL056W(gene)|ensemblfungi:YEL056W_mRNA(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006333"(chromatin assembly or disassembly)|go:"GO:0006348"|go:"GO:0016573"(histone acetylation)|go:"GO:0042393"(histone binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR022052|interpro:IPR036322|rcsb pdb:4PSW|rcsb pdb:4PSX|reactome:R-SCE-3214815|reactome:R-SCE-3214847|reactome:R-SCE-3214858|sgd:YEL056W(identity)	refseq:NP_003438.1|ensembl:ENSP00000366542|ensembl:ENSP00000507525|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR038269|mint:P49910|ensembl:ENSG00000197279(gene)|ensembl:ENST00000377325(transcript)|ensembl:ENST00000683778(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|refseq:XP_016866747.1|refseq:XP_016866748.1|refseq:XP_016866749.1|entrezgene/locuslink:7718(identity)	-	crc64:C27A91C99D9FCAB7	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:WlhnJ6TT8FLgKn4ZtoJh0tWUBQk559292	rogid:4BpNwyrtFulW7rWXuy+Y7cdgYps9606	intact-crc:5BB989612C200AB3|rigid:0LRXkxK0Tebwqa2us2WlyR13F1Q	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8N6L0	uniprotkb:P39996	intact:EBI-749265|uniprotkb:Q96MC3|ensembl:ENSP00000404220	intact:EBI-22308|uniprotkb:D3DLN3|ensemblfungi:YEL017W	psi-mi:kash5_human(display_long)|uniprotkb:KASH5(gene name)|psi-mi:KASH5(display_short)|uniprotkb:CCDC155(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 155(gene name synonym)|uniprotkb:KASH domain-containing protein 5(gene name synonym)	psi-mi:gtt3_yeast(display_long)|uniprotkb:GTT3(gene name)|psi-mi:GTT3(display_short)|uniprotkb:YEL017W(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11559419|imex:IM-24995-4834	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_653289.3|ensembl:ENSG00000161609(gene)|ensembl:ENST00000447857(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034397"(telomere localization)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051225"(spindle assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0090172"(microtubule cytoskeleton organization involved in homologous chromosome segregation)|go:"GO:0090220"(chromosome localization to nuclear envelope involved in homologous chromosome segregation)|go:"GO:0090619"(meiotic spindle pole)|interpro:IPR011992(EF-Hand type)|interpro:IPR028168|interpro:IPR028170|interpro:IPR039508|mint:Q8N6L0|rcsb pdb:6R2I|rcsb pdb:6WMF|entrezgene/locuslink:147872(identity)	sgd:S000000743|refseq:NP_010899.3|dip:DIP-2062N|mint:P39996|ensemblfungi:YEL017W(gene)|ensemblfungi:YEL017W_mRNA(transcript)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034399"(nuclear periphery)|interpro:IPR038872|sgd:YEL017W(identity)	-	-	crc64:E9F07EFD2A522006	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Wl9L7AcvDHCZuKjYLn8QgGIbZTc9606	rogid:YxznRNPatBf8VkhVPwSCfB5pCDU559292	intact-crc:1982CCD925FF727D|rigid:ZOF8n/du+kl3uNplIoAReVMTnjI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P39996	uniprotkb:Q8N6G5	intact:EBI-22308|uniprotkb:D3DLN3|ensemblfungi:YEL017W	intact:EBI-10267100|uniprotkb:Q9P1I6|uniprotkb:Q6MZJ5|uniprotkb:B3KWL7|uniprotkb:Q8TCH4|uniprotkb:Q6MZP6|ensembl:ENSP00000363590	psi-mi:gtt3_yeast(display_long)|uniprotkb:GTT3(gene name)|psi-mi:GTT3(display_short)|uniprotkb:YEL017W(locus name)	psi-mi:cgat2_human(display_long)|uniprotkb:CSGALNACT2(gene name)|psi-mi:CSGALNACT2(display_short)|uniprotkb:CHGN2(gene name synonym)|uniprotkb:Chondroitin beta-1,4-N-acetylgalactosaminyltransferase 2(gene name synonym)|uniprotkb:GALNACT2(gene name synonym)|uniprotkb:PRO0082(orf name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11559410|imex:IM-24995-4833	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000000743|refseq:NP_010899.3|dip:DIP-2062N|mint:P39996|ensemblfungi:YEL017W(gene)|ensemblfungi:YEL017W_mRNA(transcript)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034399"(nuclear periphery)|interpro:IPR038872|sgd:YEL017W(identity)	refseq:NP_061060.3|ensembl:ENSG00000169826(gene)|ensembl:ENST00000374466(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0008376"(acetylgalactosaminyltransferase activity)|go:"GO:0016020"(membrane)|go:"GO:0030166"(proteoglycan biosynthetic process)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0030206"(chondroitin sulfate biosynthetic process)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0047237"(glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity)|go:"GO:0047238"(glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity)|go:"GO:0050650"(chondroitin sulfate proteoglycan biosynthetic process)|go:"GO:0050651"(dermatan sulfate proteoglycan biosynthetic process)|go:"GO:0050652"(dermatan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process)|go:"GO:0050653"(chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process)|interpro:IPR008428(Chondroitin N-acetylgalactosaminyltransferase)|interpro:IPR029044|reactome:R-HSA-2022870|refseq:NP_001306583.1|refseq:NP_001306585.1|entrezgene/locuslink:55454(identity)	-	crc64:E9F07EFD2A522006	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:YxznRNPatBf8VkhVPwSCfB5pCDU559292	rogid:uK24H440Kn7+cnVc8C+3dV4SXw89606	intact-crc:D52CBA90E990A6D4|rigid:gWMsutxXJu4ebSSQXUfh46BadP0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q08379	uniprotkb:P40014	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	intact:EBI-22458|uniprotkb:D3DLR6|ensemblfungi:YER018C	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:spc25_yeast(display_long)|uniprotkb:YER018C(locus name)|uniprotkb:SPC25(gene name)|psi-mi:SPC25(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11559428|imex:IM-24995-4835	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N|entrezgene/locuslink:2801(identity)	refseq:NP_010934.3|sgd:S000000820|dip:DIP-2990N|mint:P40014|ensemblfungi:YER018C(gene)|ensemblfungi:YER018C_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0051301"(cell division)|go:"GO:0098653"(centromere clustering)|interpro:IPR038066|rcsb pdb:2FTX|rcsb pdb:2FV4|rcsb pdb:4GEQ|rcsb pdb:5T6J|rcsb pdb:5TCS|rcsb pdb:5TD8|rcsb pdb:7KDF|sgd:YER018C(identity)	-	-	crc64:1BED6CCFF330A5D8	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2017/05/26	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	rogid:i5gKRZA7GAjnCVzuX/qP8YmpQRA559292	intact-crc:BF9E6BEC7C81B5CD|rigid:eJgt/sLTHxO0GUAEoQCNeFv/uvk	false	sufficient binding region:383-1002	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40014	uniprotkb:P19012	intact:EBI-22458|uniprotkb:D3DLR6|ensemblfungi:YER018C	intact:EBI-739566|uniprotkb:Q53XV8|uniprotkb:Q9BUG4|uniprotkb:B3KQY1|uniprotkb:B3KRA2|uniprotkb:E0CX14|ensembl:ENSP00000254043|ensembl:ENSP00000377546	psi-mi:spc25_yeast(display_long)|uniprotkb:YER018C(locus name)|uniprotkb:SPC25(gene name)|psi-mi:SPC25(display_short)	psi-mi:k1c15_human(display_long)|uniprotkb:KRT15(gene name)|psi-mi:KRT15(display_short)|uniprotkb:KRTB(gene name synonym)|uniprotkb:Cytokeratin-15(gene name synonym)|uniprotkb:Keratin-15(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11559439|imex:IM-24995-4836	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010934.3|sgd:S000000820|dip:DIP-2990N|mint:P40014|ensemblfungi:YER018C(gene)|ensemblfungi:YER018C_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0051301"(cell division)|go:"GO:0098653"(centromere clustering)|interpro:IPR038066|rcsb pdb:2FTX|rcsb pdb:2FV4|rcsb pdb:4GEQ|rcsb pdb:5T6J|rcsb pdb:5TCS|rcsb pdb:5TD8|rcsb pdb:7KDF|sgd:YER018C(identity)	refseq:NP_002266.2|ensembl:ENSG00000171346(gene)|ensembl:ENST00000254043(transcript)|ensembl:ENST00000393976(transcript)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0008544"(epidermis development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097110"(scaffold protein binding)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR039008|mint:P19012|reactome:R-HSA-6805567|reactome:R-HSA-6809371|entrezgene/locuslink:3866(identity)	-	crc64:1BED6CCFF330A5D8	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:i5gKRZA7GAjnCVzuX/qP8YmpQRA559292	rogid:WrZQBYQvrWcfrR5ojWXrXp6spPE9606	intact-crc:45B26E3AB7C622D1|rigid:oUgxdUwOfZcG73bJAbMTmS43eWU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P37198	uniprotkb:P40014	intact:EBI-347978|intact:EBI-28983799|ensembl:ENSP00000305503|ensembl:ENSP00000407331|ensembl:ENSP00000471191|ensembl:ENSP00000473192|uniprotkb:Q6GTM2|uniprotkb:Q503A4|uniprotkb:Q96C43|uniprotkb:Q9NSL1|uniprotkb:B3KWU5	intact:EBI-22458|uniprotkb:D3DLR6|ensemblfungi:YER018C	psi-mi:nup62_human(display_long)|uniprotkb:NUP62(gene name)|psi-mi:NUP62(display_short)|uniprotkb:62 kDa nucleoporin(gene name synonym)|uniprotkb:Nucleoporin Nup62(gene name synonym)	psi-mi:spc25_yeast(display_long)|uniprotkb:YER018C(locus name)|uniprotkb:SPC25(gene name)|psi-mi:SPC25(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11559448|imex:IM-24995-4837	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_714941.1|ensembl:ENSG00000213024(gene)|ensembl:ENST00000352066(transcript)|ensembl:ENST00000422090(transcript)|ensembl:ENST00000596217(transcript)|ensembl:ENST00000597029(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005642"(annulate lamellae)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007100"(mitotic centrosome separation)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007569"(cell aging)|go:"GO:0008219"(cell death)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0003682"(chromatin binding)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0019894"(kinesin binding)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042306"(regulation of protein import into nucleus)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043069"(negative regulation of programmed cell death)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045742"(positive regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046578"(regulation of Ras protein signal transduction)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0046601"(positive regulation of centriole replication)|go:"GO:0051028"(mRNA transport)|go:"GO:0051425"(PTB domain binding)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0072686"(mitotic spindle)|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|go:"GO:0090543"(Flemming body)|go:"GO:0098534"(centriole assembly)|go:"GO:1903438"(positive regulation of mitotic cytokinetic process)|go:"GO:1904781"(positive regulation of protein localization to centrosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR007758(Nucleoporin, Nsp1-like, C-terminal)|interpro:IPR026010|interpro:IPR033072|mint:P37198|rcsb pdb:2H4D|rcsb pdb:5IJN|rcsb pdb:5IJO|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|refseq:NP_714940.1|refseq:NP_001180286.1|refseq:NP_036478.2|refseq:NP_057637.2|ensembl:ENSP00000305503|ensembl:ENSP00000407331|ensembl:ENSP00000471191|ensembl:ENSP00000473192|dip:DIP-29749N|entrezgene/locuslink:23636(identity)	refseq:NP_010934.3|sgd:S000000820|dip:DIP-2990N|mint:P40014|ensemblfungi:YER018C(gene)|ensemblfungi:YER018C_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0051301"(cell division)|go:"GO:0098653"(centromere clustering)|interpro:IPR038066|rcsb pdb:2FTX|rcsb pdb:2FV4|rcsb pdb:4GEQ|rcsb pdb:5T6J|rcsb pdb:5TCS|rcsb pdb:5TD8|rcsb pdb:7KDF|sgd:YER018C(identity)	-	-	crc64:1BED6CCFF330A5D8	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:v7mvKvTtVEnLMwcpUZIcdAzge009606	rogid:i5gKRZA7GAjnCVzuX/qP8YmpQRA559292	intact-crc:3DC0A49DC9A78AB3|rigid:oeFv3L40gCjAcSxUtWPfYIyIC0Q	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q15311	uniprotkb:P40014	intact:EBI-749285|uniprotkb:D3DUI0|ensembl:ENSP00000019317|ensembl:ENSP00000372924	intact:EBI-22458|uniprotkb:D3DLR6|ensemblfungi:YER018C	psi-mi:rbp1_human(display_long)|uniprotkb:Ral-interacting protein 1(gene name synonym)|uniprotkb:76 kDa Ral-interacting protein(gene name synonym)|uniprotkb:Dinitrophenyl S-glutathione ATPase(gene name synonym)|uniprotkb:RALBP1(gene name)|psi-mi:RALBP1(display_short)|uniprotkb:RLIP1(gene name synonym)|uniprotkb:RLIP76(gene name synonym)|uniprotkb:RLIP(gene name synonym)	psi-mi:spc25_yeast(display_long)|uniprotkb:YER018C(locus name)|uniprotkb:SPC25(gene name)|psi-mi:SPC25(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11559457|imex:IM-24995-4838	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006779.1|ensembl:ENSG00000017797(gene)|ensembl:ENST00000019317(transcript)|ensembl:ENST00000383432(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0006935"(chemotaxis)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008559"(ABC-type xenobiotic transporter activity)|go:"GO:0015431"(ABC-type glutathione S-conjugate transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032489"(regulation of Cdc42 protein signal transduction)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0055085"(transmembrane transport)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:1900753"(doxorubicin transport)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR000198(RhoGAP)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR039767|mint:Q15311|rcsb pdb:2KWH|rcsb pdb:2KWI|rcsb pdb:2MBG|rcsb pdb:6ZQT|rcsb pdb:6ZRN|reactome:R-HSA-9013148|reactome:R-HSA-9013149|entrezgene/locuslink:10928(identity)	refseq:NP_010934.3|sgd:S000000820|dip:DIP-2990N|mint:P40014|ensemblfungi:YER018C(gene)|ensemblfungi:YER018C_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0051301"(cell division)|go:"GO:0098653"(centromere clustering)|interpro:IPR038066|rcsb pdb:2FTX|rcsb pdb:2FV4|rcsb pdb:4GEQ|rcsb pdb:5T6J|rcsb pdb:5TCS|rcsb pdb:5TD8|rcsb pdb:7KDF|sgd:YER018C(identity)	-	-	crc64:1BED6CCFF330A5D8	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:6u1yy+UdGWJbJ9SiItSAp+CqeVk9606	rogid:i5gKRZA7GAjnCVzuX/qP8YmpQRA559292	intact-crc:39014D9E589FC33D|rigid:HtFQGc/1uQod6UrVVKxZtrNLaK0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40014	uniprotkb:Q8N6Y0	intact:EBI-22458|uniprotkb:D3DLR6|ensemblfungi:YER018C	intact:EBI-739895|uniprotkb:Q8NBX7|uniprotkb:Q96KH3|uniprotkb:Q9BYI8|uniprotkb:A8K7L6|uniprotkb:B2RCR9|ensembl:ENSP00000252597	psi-mi:spc25_yeast(display_long)|uniprotkb:YER018C(locus name)|uniprotkb:SPC25(gene name)|psi-mi:SPC25(display_short)	psi-mi:usbp1_human(display_long)|uniprotkb:USHBP1(gene name)|psi-mi:USHBP1(display_short)|uniprotkb:MCC-2(gene name synonym)|uniprotkb:AIE-75-binding protein(gene name synonym)|uniprotkb:AIEBP(gene name synonym)|uniprotkb:MCC2(gene name synonym)|uniprotkb:Mutated in colon cancer protein 2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11559477|imex:IM-24995-4840	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010934.3|sgd:S000000820|dip:DIP-2990N|mint:P40014|ensemblfungi:YER018C(gene)|ensemblfungi:YER018C_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0051301"(cell division)|go:"GO:0098653"(centromere clustering)|interpro:IPR038066|rcsb pdb:2FTX|rcsb pdb:2FV4|rcsb pdb:4GEQ|rcsb pdb:5T6J|rcsb pdb:5TCS|rcsb pdb:5TD8|rcsb pdb:7KDF|sgd:YER018C(identity)	refseq:NP_001284632.1|refseq:NP_114147.2|refseq:NP_001308346.1|ensembl:ENSG00000130307(gene)|ensembl:ENST00000252597(transcript)|go:"GO:0030165"(PDZ domain binding)|interpro:IPR019536|interpro:IPR040171|entrezgene/locuslink:83878(identity)	-	crc64:1BED6CCFF330A5D8	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:i5gKRZA7GAjnCVzuX/qP8YmpQRA559292	rogid:vY1qx73Ju/z7WDu6k1kd10ZDVRo9606	intact-crc:F540C70055D91502|rigid:rDgEicRDXpzi4eKB+1VHat4fpJ0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40014	uniprotkb:Q6P1W5	intact:EBI-22458|uniprotkb:D3DLR6|ensemblfungi:YER018C	intact:EBI-946029|uniprotkb:B3KVT1|uniprotkb:Q96IC8|ensembl:ENSP00000435634|uniprotkb:D3DPR3|uniprotkb:E9PJ76	psi-mi:spc25_yeast(display_long)|uniprotkb:YER018C(locus name)|uniprotkb:SPC25(gene name)|psi-mi:SPC25(display_short)	psi-mi:ca094_human(display_long)|uniprotkb:C1orf94(gene name)|psi-mi:C1orf94(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11559466|imex:IM-24995-4839	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010934.3|sgd:S000000820|dip:DIP-2990N|mint:P40014|ensemblfungi:YER018C(gene)|ensemblfungi:YER018C_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0051301"(cell division)|go:"GO:0098653"(centromere clustering)|interpro:IPR038066|rcsb pdb:2FTX|rcsb pdb:2FV4|rcsb pdb:4GEQ|rcsb pdb:5T6J|rcsb pdb:5TCS|rcsb pdb:5TD8|rcsb pdb:7KDF|sgd:YER018C(identity)	refseq:NP_001128206.1|refseq:NP_116273.2|ensembl:ENSG00000142698(gene)|ensembl:ENST00000488417(transcript)|interpro:IPR031496|entrezgene/locuslink:84970(identity)	-	crc64:1BED6CCFF330A5D8	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:i5gKRZA7GAjnCVzuX/qP8YmpQRA559292	rogid:y1o4xWvTl2CBA1J7jsP7y8ZjLzM9606	intact-crc:00F610331696D7BA|rigid:7whOMEJOuuXKJBnESrRfZGxlaI0	false	-	sufficient binding region:191-598	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40045	uniprotkb:O76081-6	intact:EBI-22573|uniprotkb:D3DLX6|ensemblfungi:YER071C	intact:EBI-10178530|ensembl:ENSP00000276500	psi-mi:tda2_yeast(display_long)|uniprotkb:YER071C(locus name)|uniprotkb:TDA2(gene name)|psi-mi:TDA2(display_short)	psi-mi:o76081-6(display_long)|uniprotkb:RGS20(gene name)|psi-mi:RGS20(display_short)|uniprotkb:Gz-selective GTPase-activating protein(gene name synonym)|uniprotkb:RGSZ1(gene name synonym)|uniprotkb:Regulator of G-protein signaling Z1(gene name synonym)|uniprotkb:Regulator of Gz-selective protein signaling 1(gene name synonym)|uniprotkb:ZGAP1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11559495|imex:IM-24995-4842	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010994.3|sgd:S000000873|dip:DIP-4134N|mint:P40045|ensemblfungi:YER071C(gene)|ensemblfungi:YER071C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0030479"(actin cortical patch)|go:"GO:0030837"(negative regulation of actin filament polymerization)|go:"GO:0043332"(mating projection tip)|go:"GO:0110131"(Aim21-Tda2 complex)|interpro:IPR005334(Tctex-1)|interpro:IPR038586|rcsb pdb:5VKY|sgd:YER071C(identity)	intact:EBI-1052678(isoform-parent)|uniprotkb:O76081-6(isoform-parent)|ensembl:ENSG00000147509(gene)|ensembl:ENST00000276500(transcript)|entrezgene/locuslink:8601(identity)	-	crc64:2F5CD27AF0C9AFE3	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:xlo2Qkef4nrF1u7WQ+p7SjixmFs559292	rogid:5ddWx+4uSAxIhugOqlfdCIOD8sM9606	intact-crc:D4C1CD3D008F9928|rigid:Se6nOEof1Yp+d3QlMTxO8dcz+O4	false	-	sufficient binding region:25-241	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40014	uniprotkb:Q9UKT9	intact:EBI-22458|uniprotkb:D3DLR6|ensemblfungi:YER018C	intact:EBI-747204|uniprotkb:Q8WWQ9|uniprotkb:Q8WWR0|uniprotkb:Q8WWR1|uniprotkb:Q8WWR2|uniprotkb:Q8WWR3|uniprotkb:Q8N574|uniprotkb:B4DVV5|uniprotkb:Q69BL6|uniprotkb:Q69BL7|uniprotkb:Q69BL8|uniprotkb:Q69BL9|uniprotkb:Q69BM0|uniprotkb:Q69BM1|uniprotkb:Q69BM2|uniprotkb:Q69BM3|uniprotkb:Q69BM5|ensembl:ENSP00000344544	psi-mi:spc25_yeast(display_long)|uniprotkb:YER018C(locus name)|uniprotkb:SPC25(gene name)|psi-mi:SPC25(display_short)	psi-mi:ikzf3_human(display_long)|uniprotkb:ZNFN1A3(gene name synonym)|uniprotkb:Ikaros family zinc finger protein 3(gene name synonym)|uniprotkb:IKZF3(gene name)|psi-mi:IKZF3(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11559486|imex:IM-24995-4841	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010934.3|sgd:S000000820|dip:DIP-2990N|mint:P40014|ensemblfungi:YER018C(gene)|ensemblfungi:YER018C_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0051301"(cell division)|go:"GO:0098653"(centromere clustering)|interpro:IPR038066|rcsb pdb:2FTX|rcsb pdb:2FV4|rcsb pdb:4GEQ|rcsb pdb:5T6J|rcsb pdb:5TCS|rcsb pdb:5TD8|rcsb pdb:7KDF|sgd:YER018C(identity)	refseq:NP_001271443.1|refseq:NP_001271444.1|refseq:NP_036613.2|refseq:NP_899051.1|refseq:NP_899052.1|refseq:NP_899053.1|refseq:NP_899054.1|refseq:NP_899055.1|refseq:NP_001271445.1|refseq:NP_001244337.1|refseq:NP_001244338.1|refseq:NP_001244339.1|refseq:NP_001244340.1|refseq:NP_001244341.1|refseq:NP_001244342.1|refseq:NP_001244343.1|ensembl:ENSG00000161405(gene)|ensembl:ENST00000346872(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007498"(mesoderm development)|go:"GO:0009617"(response to bacterium)|go:"GO:0030888"(regulation of B cell proliferation)|go:"GO:0042113"(B cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045577"(regulation of B cell differentiation)|go:"GO:0045619"(regulation of lymphocyte differentiation)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|go:"GO:0046872"(metal ion binding)|dip:DIP-56975N|entrezgene/locuslink:22806(identity)	-	crc64:1BED6CCFF330A5D8	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:i5gKRZA7GAjnCVzuX/qP8YmpQRA559292	rogid:2Kp6LefSLfK5VIiE6DmQusFIfMY9606	intact-crc:FCD7CC4ADA837D1F|rigid:fjco9Hw8L8MpKcC5f63nO4QBPYE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40045	uniprotkb:P19012	intact:EBI-22573|uniprotkb:D3DLX6|ensemblfungi:YER071C	intact:EBI-739566|uniprotkb:Q53XV8|uniprotkb:Q9BUG4|uniprotkb:B3KQY1|uniprotkb:B3KRA2|uniprotkb:E0CX14|ensembl:ENSP00000254043|ensembl:ENSP00000377546	psi-mi:tda2_yeast(display_long)|uniprotkb:YER071C(locus name)|uniprotkb:TDA2(gene name)|psi-mi:TDA2(display_short)	psi-mi:k1c15_human(display_long)|uniprotkb:KRT15(gene name)|psi-mi:KRT15(display_short)|uniprotkb:KRTB(gene name synonym)|uniprotkb:Cytokeratin-15(gene name synonym)|uniprotkb:Keratin-15(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11559506|imex:IM-24995-4843	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010994.3|sgd:S000000873|dip:DIP-4134N|mint:P40045|ensemblfungi:YER071C(gene)|ensemblfungi:YER071C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0030479"(actin cortical patch)|go:"GO:0030837"(negative regulation of actin filament polymerization)|go:"GO:0043332"(mating projection tip)|go:"GO:0110131"(Aim21-Tda2 complex)|interpro:IPR005334(Tctex-1)|interpro:IPR038586|rcsb pdb:5VKY|sgd:YER071C(identity)	refseq:NP_002266.2|ensembl:ENSG00000171346(gene)|ensembl:ENST00000254043(transcript)|ensembl:ENST00000393976(transcript)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0008544"(epidermis development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097110"(scaffold protein binding)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR039008|mint:P19012|reactome:R-HSA-6805567|reactome:R-HSA-6809371|entrezgene/locuslink:3866(identity)	-	crc64:2F5CD27AF0C9AFE3	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:xlo2Qkef4nrF1u7WQ+p7SjixmFs559292	rogid:WrZQBYQvrWcfrR5ojWXrXp6spPE9606	intact-crc:957D5372E7F02F7F|rigid:Bj3x2ESld+NXJ5RwNeaNYdaHqco	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96BA8	uniprotkb:P40074	intact:EBI-6942903|ensembl:ENSP00000481956|intact:MINT-268046|intact:MINT-8162577|uniprotkb:Q8N2D5|uniprotkb:Q96CP0	intact:EBI-22666|uniprotkb:D3DM25|ensemblfungi:YER119C	psi-mi:cr3l1_human(display_long)|uniprotkb:CREB3L1(gene name)|psi-mi:CREB3L1(display_short)|uniprotkb:OASIS(gene name synonym)|uniprotkb:PSEC0238(orf name)|uniprotkb:Old astrocyte specifically-induced substance(gene name synonym)	psi-mi:avt6_yeast(display_long)|uniprotkb:YER119C(locus name)|uniprotkb:AVT6(gene name)|psi-mi:AVT6(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11559524|imex:IM-24995-4845	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157613(gene)|ensembl:ENST00000621158(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0070278"(extracellular matrix constituent secretion)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029805|mint:Q96BA8|reactome:R-HSA-8874211|refseq:NP_443086.1|entrezgene/locuslink:90993(identity)	refseq:NP_011044.1|sgd:S000000921|dip:DIP-4489N|ensemblfungi:YER119C(gene)|ensemblfungi:YER119C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0003333"(amino acid transmembrane transport)|go:"GO:0005290"(L-histidine transmembrane transporter activity)|go:"GO:0005302"(L-tyrosine transmembrane transporter activity)|go:"GO:0005313"(L-glutamate transmembrane transporter activity)|go:"GO:0015171"(amino acid transmembrane transporter activity)|go:"GO:0015183"(L-aspartate transmembrane transporter activity)|go:"GO:0015189"(L-lysine transmembrane transporter activity)|go:"GO:0015194"(L-serine transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032974"(amino acid transmembrane export from vacuole)|go:"GO:0055085"(transmembrane transport)|go:"GO:0061459"(L-arginine transmembrane transporter activity)|interpro:IPR013057(Amino acid transporter, transmembrane)|sgd:YER119C(identity)	-	comment:mint|function:"Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE"	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:sMWUFmBeBBCO+T0Y2CuB/un1lBg9606	rogid:KSuV+ucakPCtl1xQLMI6W54S7r0559292	intact-crc:B090E8A7B42CF027|rigid:ejPtOwiLtFx+6GXyn4cOSdiuTUg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q13049	uniprotkb:P40070	intact:EBI-742790|ensembl:ENSP00000363095|ensembl:ENSP00000408292|uniprotkb:Q9NQP8	intact:EBI-188|uniprotkb:Q07091|uniprotkb:D3DM18|ensemblfungi:YER112W	psi-mi:tri32_human(display_long)|uniprotkb:Zinc finger protein HT2A(gene name synonym)|uniprotkb:72 kDa Tat-interacting protein(gene name synonym)|uniprotkb:TRIM32(gene name)|psi-mi:TRIM32(display_short)|uniprotkb:HT2A(gene name synonym)|uniprotkb:Tripartite motif-containing protein 32(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM32(gene name synonym)	psi-mi:lsm4_yeast(display_long)|uniprotkb:LSM4(gene name)|psi-mi:LSM4(display_short)|uniprotkb:SDB23(gene name synonym)|uniprotkb:USS1(gene name synonym)|uniprotkb:YER112W(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11559515|imex:IM-24995-4844	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0043621"(protein self-association)|go:"GO:0045087"(innate immune response)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051155"(positive regulation of striated muscle cell differentiation)|go:"GO:0061564"(axon development)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1902187"|go:"GO:1902230"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:1903265"(positive regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:1903883"(positive regulation of interleukin-17-mediated signaling pathway)|go:"GO:1903886"("positive regulation of chemokine (C-C motif) ligand 20 production")|go:"GO:2000147"(positive regulation of cell motility)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENSG00000119401(gene)|ensembl:ENST00000373983(transcript)|ensembl:ENST00000450136(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001894"(tissue homeostasis)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005863"(striated muscle myosin thick filament)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007014"(actin ubiquitination)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009411"(response to UV)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0017022"(myosin binding)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030957"(Tat protein binding)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034612"(response to tumor necrosis factor)|go:"GO:0042802"(identical protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|interpro:IPR000315(Zinc finger, B-box)|refseq:NP_001093149.1|refseq:XP_011516700.1|refseq:NP_036342.2|refseq:XP_005251870.1|interpro:IPR001258(NHL repeat)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR013017(NHL repeat, subgroup)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR027370|mint:Q13049|rcsb pdb:2CT2|rcsb pdb:5FEY|reactome:R-HSA-3134975|reactome:R-HSA-983168|refseq:XP_016869975.1|entrezgene/locuslink:22954(identity)	sgd:S000000914|refseq:NP_011037.3|mint:P40070|dip:DIP-848N|ensemblfungi:YER112W(gene)|ensemblfungi:YER112W_mRNA(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000932"(P-body)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005688"(U6 snRNP)|go:"GO:0005730"(nucleolus)|go:"GO:0005732"("sno(s)RNA-containing ribonucleoprotein complex")|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0008033"(tRNA processing)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0033962"(P-body assembly)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0097526"(spliceosomal tri-snRNP complex)|go:"GO:1990726"(Lsm1-7-Pat1 complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR027141|interpro:IPR034101|rcsb pdb:3JCM|rcsb pdb:4C8Q|rcsb pdb:4C92|rcsb pdb:4M75|rcsb pdb:4M77|rcsb pdb:4M78|rcsb pdb:4M7A|rcsb pdb:4M7D|rcsb pdb:5GAN|rcsb pdb:5NRL|rcsb pdb:5VSU|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:6ASO|reactome:R-SCE-430039|sgd:YER112W(identity)	-	-	crc64:69CAC1F01D5BFA98	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:XuqprQd10kSpsuyGs+FSdzIdJ/Y9606	rogid:Sz8HLaybwgxCRbeCESby3YThqeM559292	intact-crc:EEEC5BDD558B28F8|rigid:e+QfnPkpuY4D6PAkml9j4dlL/tg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40075	uniprotkb:O15209	intact:EBI-16735|ensemblfungi:YER120W|uniprotkb:D3DM26	intact:EBI-723574|uniprotkb:Q5HYV4|uniprotkb:Q5STL0|uniprotkb:Q5STR7|uniprotkb:Q8WV82|ensembl:ENSP00000372683|ensembl:ENSP00000388191|ensembl:ENSP00000393514|ensembl:ENSP00000396292|ensembl:ENSP00000404403|ensembl:ENSP00000407545|uniprotkb:B0V007	psi-mi:scs2_yeast(display_long)|uniprotkb:YER120W(locus name)|uniprotkb:SCS2(gene name)|psi-mi:SCS2(display_short)|uniprotkb:VAP homolog 1(gene name synonym)|uniprotkb:Choline sensitivity suppressor protein 2(gene name synonym)	psi-mi:zbt22_human(display_long)|uniprotkb:Zinc finger protein 297(gene name synonym)|uniprotkb:Protein BING1(gene name synonym)|uniprotkb:Zinc finger and BTB domain-containing protein 22A(gene name synonym)|uniprotkb:ZBTB22(gene name)|psi-mi:ZBTB22(display_short)|uniprotkb:BING1(gene name synonym)|uniprotkb:ZBTB22A(gene name synonym)|uniprotkb:ZNF297(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11559533|imex:IM-24995-4846	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011046.3|ensemblfungi:YER120W(gene)|ensemblfungi:YER120W_mRNA(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042308"(negative regulation of protein import into nucleus)|go:"GO:0048309"(endoplasmic reticulum inheritance)|go:"GO:0060304"(regulation of phosphatidylinositol dephosphorylation)|go:"GO:0005886"(plasma membrane)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0061163"(endoplasmic reticulum polarization)|go:"GO:0006348"|go:"GO:0061817"(endoplasmic reticulum-plasma membrane tethering)|go:"GO:0008654"(phospholipid biosynthetic process)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032377"(regulation of intracellular lipid transport)|go:"GO:0033149"(FFAT motif binding)|go:"GO:0071561"(nucleus-vacuole junction)|go:"GO:0090158"(endoplasmic reticulum membrane organization)|interpro:IPR000535(Major sperm protein)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016763(Vesicle-associated membrane protein)|rcsb pdb:6LP4|reactome:R-SCE-6798695|reactome:R-SCE-9609523|sgd:S000000922|dip:DIP-2272N|mint:P40075|sgd:YER120W(identity)	refseq:NP_001138810.1|refseq:NP_005444.4|ensembl:ENSG00000206280(gene)|ensembl:ENSG00000227780(gene)|ensembl:ENSG00000229253(gene)|ensembl:ENSG00000236104(gene)|ensembl:ENSG00000237056(gene)|ensembl:ENST00000418724(transcript)|ensembl:ENST00000431845(transcript)|ensembl:ENST00000445320(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR029833|interpro:IPR036236|ensembl:ENST00000383196(transcript)|ensembl:ENST00000416097(transcript)|ensembl:ENST00000418540(transcript)|dip:DIP-62047N|entrezgene/locuslink:9278(identity)	-	crc64:45390E24E31D392E	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:P5Pirj7wRxTi5bdoNs8lCzzTNPI559292	rogid:/u3Is9uJ0nS5Ru7xZKg4MqF6dzE9606	intact-crc:54125B58593C2041|rigid:Pxr8b2kLMXZ4AHOUGCSBcjtKp3M	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40078	uniprotkb:O14641	intact:EBI-22681|uniprotkb:D3DM32|ensemblfungi:YER126C	intact:EBI-740850|ensembl:ENSP00000005340|uniprotkb:Q53XM0|uniprotkb:D3DTN3	psi-mi:nsa2_yeast(display_long)|uniprotkb:YER126C(locus name)|uniprotkb:SYGP-ORF47(orf name)|uniprotkb:NSA2(gene name)|psi-mi:NSA2(display_short)|uniprotkb:NOP7-associated protein 2(gene name synonym)	psi-mi:dvl2_human(display_long)|uniprotkb:DSH homolog 2(gene name synonym)|uniprotkb:DVL2(gene name)|psi-mi:DVL2(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11559542|imex:IM-24995-4847	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011052.1|sgd:S000000928|dip:DIP-1892N|mint:P40078|ensemblfungi:YER126C(gene)|ensemblfungi:YER126C_mRNA(transcript)|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000466"("maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0042273"(ribosomal large subunit biogenesis)|interpro:IPR022309|interpro:IPR039411|rcsb pdb:3JCT|rcsb pdb:4WJV|rcsb pdb:6ELZ|rcsb pdb:6EM1|rcsb pdb:6EM5|rcsb pdb:6FT6|rcsb pdb:6M62|rcsb pdb:6N8J|rcsb pdb:7BT6|rcsb pdb:7BTB|sgd:YER126C(identity)	refseq:NP_004413.1|ensembl:ENSG00000004975(gene)|ensembl:ENST00000005340(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005109"(frizzled binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0007507"(heart development)|go:"GO:0016235"(aggresome)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044340"(canonical Wnt signaling pathway involved in regulation of cell proliferation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0150012"(positive regulation of neuron projection arborization)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008341(Dishevelled-2 region)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:O14641|rcsb pdb:2REY|rcsb pdb:3CBX|rcsb pdb:3CBY|rcsb pdb:3CBZ|rcsb pdb:3CC0|rcsb pdb:4WIP|rcsb pdb:5LNP|rcsb pdb:5SUY|rcsb pdb:5SUZ|rcsb pdb:6IW3|rcsb pdb:6JCK|reactome:R-HSA-201681|reactome:R-HSA-201688|reactome:R-HSA-2028269|reactome:R-HSA-4086400|reactome:R-HSA-4608870|reactome:R-HSA-4641258|reactome:R-HSA-4641262|reactome:R-HSA-5099900|reactome:R-HSA-5368598|reactome:R-HSA-5663220|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9673324|ensembl:ENSP00000005340|dip:DIP-34433N|entrezgene/locuslink:1856(identity)	-	crc64:545C8B4250BCB0C9	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:ru6dofBbaVkHM+0tunQ4n36y98M559292	rogid:2Vdc8oRnT4Mz/j+EXQXrL3AszOc9606	intact-crc:54CC737EA196B8CD|rigid:tWCDx+BU2anm9C6WOZ01tGn0vL8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40087	uniprotkb:O14641	intact:EBI-5717|uniprotkb:D3DM50|ensemblfungi:YER143W	intact:EBI-740850|ensembl:ENSP00000005340|uniprotkb:Q53XM0|uniprotkb:D3DTN3	psi-mi:ddi1_yeast(display_long)|uniprotkb:DDI1(gene name)|psi-mi:DDI1(display_short)|uniprotkb:v-SNARE-master 1(gene name synonym)|uniprotkb:VSM1(gene name synonym)|uniprotkb:YER143W(locus name)	psi-mi:dvl2_human(display_long)|uniprotkb:DSH homolog 2(gene name synonym)|uniprotkb:DVL2(gene name)|psi-mi:DVL2(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11559551|imex:IM-24995-4848	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000000945|refseq:NP_011070.3|dip:DIP-1216N|mint:P40087|rcsb pdb:2MRP|rcsb pdb:2MWS|rcsb pdb:2N7E|rcsb pdb:4Z2Z|rcsb pdb:5KES|ensemblfungi:YER143W(gene)|ensemblfungi:YER143W_mRNA(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0004190"(aspartic-type endopeptidase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0009306"(protein secretion)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043328"(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0072710"(response to hydroxyurea)|go:"GO:1904855"(proteasome regulatory particle binding)|interpro:IPR001995(Peptidase A2A, retrovirus, catalytic)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR019103|interpro:IPR021109|interpro:IPR033882|rcsb pdb:2I1A|rcsb pdb:2MR9|rcsb pdb:2MRO|sgd:YER143W(identity)	refseq:NP_004413.1|ensembl:ENSG00000004975(gene)|ensembl:ENST00000005340(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005109"(frizzled binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0007507"(heart development)|go:"GO:0016235"(aggresome)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044340"(canonical Wnt signaling pathway involved in regulation of cell proliferation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0150012"(positive regulation of neuron projection arborization)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008341(Dishevelled-2 region)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:O14641|rcsb pdb:2REY|rcsb pdb:3CBX|rcsb pdb:3CBY|rcsb pdb:3CBZ|rcsb pdb:3CC0|rcsb pdb:4WIP|rcsb pdb:5LNP|rcsb pdb:5SUY|rcsb pdb:5SUZ|rcsb pdb:6IW3|rcsb pdb:6JCK|reactome:R-HSA-201681|reactome:R-HSA-201688|reactome:R-HSA-2028269|reactome:R-HSA-4086400|reactome:R-HSA-4608870|reactome:R-HSA-4641258|reactome:R-HSA-4641262|reactome:R-HSA-5099900|reactome:R-HSA-5368598|reactome:R-HSA-5663220|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9673324|ensembl:ENSP00000005340|dip:DIP-34433N|entrezgene/locuslink:1856(identity)	-	crc64:B43425B029B7658B	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:DHcLrKv/gQNKEXCievX6k6ikKL0559292	rogid:2Vdc8oRnT4Mz/j+EXQXrL3AszOc9606	intact-crc:B6F526BA7EB14E51|rigid:GeUpq3+MJUcBavhPhRoJUMMCLdE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8WTU0	uniprotkb:P40087	intact:EBI-748248|uniprotkb:Q7Z4U6|uniprotkb:Q8WTS3|ensembl:ENSP00000302805	intact:EBI-5717|uniprotkb:D3DM50|ensemblfungi:YER143W	psi-mi:ddi1_human(display_long)|uniprotkb:DDI1(gene name)|psi-mi:DDI1(display_short)	psi-mi:ddi1_yeast(display_long)|uniprotkb:DDI1(gene name)|psi-mi:DDI1(display_short)|uniprotkb:v-SNARE-master 1(gene name synonym)|uniprotkb:VSM1(gene name synonym)|uniprotkb:YER143W(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11559560|imex:IM-24995-4849	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001001711.1|interpro:IPR000626(Ubiquitin)|interpro:IPR019103|interpro:IPR021109|interpro:IPR029071|interpro:IPR033882|rcsb pdb:3S8I|go:"GO:0097752"(regulation of DNA stability)|ensembl:ENSG00000170967(gene)|ensembl:ENST00000302259(transcript)|go:"GO:0004190"(aspartic-type endopeptidase activity)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0072711"(cellular response to hydroxyurea)|dip:DIP-60626N|entrezgene/locuslink:414301(identity)	sgd:S000000945|refseq:NP_011070.3|dip:DIP-1216N|mint:P40087|rcsb pdb:2MRP|rcsb pdb:2MWS|rcsb pdb:2N7E|rcsb pdb:4Z2Z|rcsb pdb:5KES|ensemblfungi:YER143W(gene)|ensemblfungi:YER143W_mRNA(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0004190"(aspartic-type endopeptidase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0009306"(protein secretion)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043328"(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0072710"(response to hydroxyurea)|go:"GO:1904855"(proteasome regulatory particle binding)|interpro:IPR001995(Peptidase A2A, retrovirus, catalytic)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR019103|interpro:IPR021109|interpro:IPR033882|rcsb pdb:2I1A|rcsb pdb:2MR9|rcsb pdb:2MRO|sgd:YER143W(identity)	-	-	crc64:B43425B029B7658B	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:000xGRvL5rBRHv7/sbuzB7i7Wtc9606	rogid:DHcLrKv/gQNKEXCievX6k6ikKL0559292	intact-crc:C729E83D1A927C65|rigid:wvG9/y0FG/QD7dqPs2aJuOh5m3I	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UMX0	uniprotkb:P40092	intact:EBI-741480|uniprotkb:Q8IXS9|uniprotkb:Q8N2Q3|uniprotkb:Q9H0T8|uniprotkb:Q9H3R4|uniprotkb:Q9HAZ5|intact:EBI-28967608|ensembl:ENSP00000365576|uniprotkb:Q5T6J5|uniprotkb:Q5T6J9|uniprotkb:A0A024R284	intact:EBI-22721|uniprotkb:D3DM57|ensemblfungi:YER150W	psi-mi:ubql1_human(display_long)|uniprotkb:Protein linking IAP with cytoskeleton 1(gene name synonym)|uniprotkb:UBQLN1(gene name)|psi-mi:UBQLN1(display_short)|uniprotkb:DA41(gene name synonym)|uniprotkb:PLIC1(gene name synonym)	psi-mi:spi1_yeast(display_long)|uniprotkb:YER150W(locus name)|uniprotkb:SPI1(gene name)|psi-mi:SPI1(display_short)|uniprotkb:Stationary phase-induced protein 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11559570|imex:IM-24995-4850	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000257468|ensembl:ENSP00000257468|ensembl:ENSP00000365576|ensembl:ENSG00000135018(gene)|ensembl:ENST00000376395(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000502"(proteasome complex)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016235"(aggresome)|go:"GO:0016236"(macroautophagy)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0019900"(kinase binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035973"(aggrephagy)|go:"GO:0042802"(identical protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0097352"(autophagosome maturation)|go:"GO:1901340"(negative regulation of store-operated calcium channel activity)|go:"GO:1902175"(regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)|interpro:IPR000626(Ubiquitin)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR028430|interpro:IPR029071|mint:Q9UMX0|rcsb pdb:2JY5|rcsb pdb:2JY6|rcsb pdb:2KLC|reactome:R-HSA-8856825|refseq:NP_038466.2|refseq:NP_444295.1|dip:DIP-41629N|entrezgene/locuslink:29979(identity)	sgd:S000000952|refseq:NP_011077.1|dip:DIP-2064N|go:"GO:0071944"(cell periphery)|interpro:IPR038843|go:"GO:0031505"(fungal-type cell wall organization)|ensemblfungi:YER150W(gene)|ensemblfungi:YER150W_mRNA(transcript)|go:"GO:0005199"(structural constituent of cell wall)|go:"GO:0005576"(extracellular region)|go:"GO:0009277"(fungal-type cell wall)|go:"GO:0010447"(response to acidic pH)|go:"GO:0031225"(anchored component of membrane)|sgd:YER150W(identity)	-	-	crc64:F65B20225FE2A5ED	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:nCFfZbGCTvRYaXhQ4R99XblslvM9606	rogid:0S1OQwJ9EXGKjALQ4oF2uW7KCjc559292	intact-crc:2F3FF1F661D870CF|rigid:01eOMBD/vl6nTSTP4Kt9aXWkDe0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:A0A0C4DFM5	uniprotkb:P40099	intact:EBI-11530418|ensembl:ENSP00000239926	intact:EBI-2059710|uniprotkb:D3DM92|ensemblfungi:YER183C	psi-mi:a0a0c4dfm5_human(display_long)|uniprotkb:hCG_39937(orf name)|uniprotkb:MYOT(gene name)|psi-mi:MYOT(display_short)	psi-mi:fthc_yeast(display_long)|uniprotkb:FAU1(gene name)|psi-mi:FAU1(display_short)|uniprotkb:5,10-methenyl-tetrahydrofolate synthetase(gene name synonym)|uniprotkb:YER183C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11559579|imex:IM-24995-4851	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006781.1|ensembl:ENSG00000120729(gene)|ensembl:ENST00000239926(transcript)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|entrezgene/locuslink:9499(identity)	reactome:R-SCE-196757|refseq:NP_011110.1|sgd:S000000985|interpro:IPR002698(5-formyltetrahydrofolate cyclo-ligase)|interpro:IPR024185|interpro:IPR037171|ensemblfungi:YER183C(gene)|ensemblfungi:YER183C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0009396"(folic acid-containing compound biosynthetic process)|go:"GO:0030272"(5-formyltetrahydrofolate cyclo-ligase activity)|go:"GO:0035999"(tetrahydrofolate interconversion)|sgd:YER183C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:ggHzlR2dbSQfddxEwJplKIQXGK89606	rogid:dS0v0wrvp9isCvc/Sp4d5aiOhnY559292	intact-crc:8C1EB25BF90D591C|rigid:a7sWIXwPEmsQ7O7UxJl9GvBu72M	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40099	uniprotkb:P13196	intact:EBI-2059710|uniprotkb:D3DM92|ensemblfungi:YER183C	intact:EBI-3905054|ensembl:ENSP00000309259|ensembl:ENSP00000378416|ensembl:ENSP00000417719|ensembl:ENSP00000418779	psi-mi:fthc_yeast(display_long)|uniprotkb:FAU1(gene name)|psi-mi:FAU1(display_short)|uniprotkb:5,10-methenyl-tetrahydrofolate synthetase(gene name synonym)|uniprotkb:YER183C(locus name)	psi-mi:hem1_human(display_long)|uniprotkb:ALAS1(gene name)|psi-mi:ALAS1(display_short)|uniprotkb:ALAS3(gene name synonym)|uniprotkb:ALASH(gene name synonym)|uniprotkb:5-aminolevulinic acid synthase 1(gene name synonym)|uniprotkb:Delta-ALA synthase 1(gene name synonym)|uniprotkb:Delta-aminolevulinate synthase 1(gene name synonym)|uniprotkb:OK/SW-cl.121(orf name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11559588|imex:IM-24995-4852	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	reactome:R-SCE-196757|refseq:NP_011110.1|sgd:S000000985|interpro:IPR002698(5-formyltetrahydrofolate cyclo-ligase)|interpro:IPR024185|interpro:IPR037171|ensemblfungi:YER183C(gene)|ensemblfungi:YER183C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0009396"(folic acid-containing compound biosynthetic process)|go:"GO:0030272"(5-formyltetrahydrofolate cyclo-ligase activity)|go:"GO:0035999"(tetrahydrofolate interconversion)|sgd:YER183C(identity)	refseq:NP_001291372.1|refseq:NP_001291373.1|refseq:NP_000679.1|refseq:NP_954635.1|go:"GO:0006783"(heme biosynthetic process)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0042541"(hemoglobin biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0048821"(erythrocyte development)|ensembl:ENSG00000023330(gene)|ensembl:ENST00000310271(transcript)|ensembl:ENST00000394965(transcript)|ensembl:ENST00000469224(transcript)|ensembl:ENST00000484952(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0003870"(5-aminolevulinate synthase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|interpro:IPR001917(Aminotransferase, class-II, pyridoxal-phosphate binding site)|interpro:IPR004839(Aminotransferase, class I and II)|interpro:IPR010961(Tetrapyrrole biosynthesis, 5-aminolevulinic acid synthase)|interpro:IPR015118(5-aminolevulinate synthase presequence)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|mint:P13196|reactome:R-HSA-189451|reactome:R-HSA-1989781|reactome:R-HSA-2151201|go:"GO:0006782"(protoporphyrinogen IX biosynthetic process)|entrezgene/locuslink:211(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:dS0v0wrvp9isCvc/Sp4d5aiOhnY559292	rogid:HFjJ6zrRF9UYD7LMB6A3CcxcS7c9606	intact-crc:6D16B3FB6D4AAC1E|rigid:ux1CwXxyarshXQ76Iz25Fcf2c8A	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96BA8	uniprotkb:P40107	intact:EBI-6942903|ensembl:ENSP00000481956|intact:MINT-268046|intact:MINT-8162577|uniprotkb:Q8N2D5|uniprotkb:Q96CP0	intact:EBI-7764|uniprotkb:D6VVB0|ensemblfungi:YGL225W	psi-mi:cr3l1_human(display_long)|uniprotkb:CREB3L1(gene name)|psi-mi:CREB3L1(display_short)|uniprotkb:OASIS(gene name synonym)|uniprotkb:PSEC0238(orf name)|uniprotkb:Old astrocyte specifically-induced substance(gene name synonym)	psi-mi:gmt1_yeast(display_long)|uniprotkb:VRG4(gene name)|psi-mi:VRG4(display_short)|uniprotkb:MCD3(gene name synonym)|uniprotkb:VAN2(gene name synonym)|uniprotkb:GOG5(gene name synonym)|uniprotkb:LDB3(gene name synonym)|uniprotkb:Vanadate resistance glycosylation protein 4(gene name synonym)|uniprotkb:Low dye-binding protein 3(gene name synonym)|uniprotkb:Morphogenesis checkpoint-dependent protein 3(gene name synonym)|uniprotkb:VIG4(gene name synonym)|uniprotkb:YGL225W(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11559597|imex:IM-24995-4853	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157613(gene)|ensembl:ENST00000621158(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0070278"(extracellular matrix constituent secretion)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029805|mint:Q96BA8|reactome:R-HSA-8874211|refseq:NP_443086.1|entrezgene/locuslink:90993(identity)	refseq:NP_011290.1|sgd:S000003193|dip:DIP-5108N|ensemblfungi:YGL225W(gene)|ensemblfungi:YGL225W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005458"(GDP-mannose transmembrane transporter activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0008643"(carbohydrate transport)|go:"GO:0015297"(antiporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:1990570"(GDP-mannose transmembrane transport)|interpro:IPR038736|rcsb pdb:5OGE|rcsb pdb:5OGK|rcsb pdb:6QSK|sgd:YGL225W(identity)	-	comment:mint|function:"Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE"	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:sMWUFmBeBBCO+T0Y2CuB/un1lBg9606	rogid:ZYzY/DU+8rq6BJZz/a4LlZa8I4w559292	intact-crc:3FCA85C1D92F4F93|rigid:ZzXUPAYRI5Hrp+MRYH8Rif5ZS9A	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96BA8	uniprotkb:P40152	intact:EBI-6942903|ensembl:ENSP00000481956|intact:MINT-268046|intact:MINT-8162577|uniprotkb:Q8N2D5|uniprotkb:Q96CP0	intact:EBI-29148|uniprotkb:D6W0X3|ensemblfungi:YNL217W	psi-mi:cr3l1_human(display_long)|uniprotkb:CREB3L1(gene name)|psi-mi:CREB3L1(display_short)|uniprotkb:OASIS(gene name synonym)|uniprotkb:PSEC0238(orf name)|uniprotkb:Old astrocyte specifically-induced substance(gene name synonym)	psi-mi:ynv7_yeast(display_long)|uniprotkb:N1306(orf name)|uniprotkb:YNL217W(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11559625|imex:IM-24995-4856	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157613(gene)|ensembl:ENST00000621158(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0070278"(extracellular matrix constituent secretion)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029805|mint:Q96BA8|reactome:R-HSA-8874211|refseq:NP_443086.1|entrezgene/locuslink:90993(identity)	refseq:NP_014182.1|sgd:S000005161|dip:DIP-4934N|ensemblfungi:YNL217W(gene)|ensemblfungi:YNL217W_mRNA(transcript)|go:"GO:0000298"(endopolyphosphatase activity)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005775"(vacuolar lumen)|go:"GO:0006798"(polyphosphate catabolic process)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR029052|sgd:YNL217W(identity)	-	comment:mint|function:"Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE"	crc64:D69F22A94C4C6684	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:sMWUFmBeBBCO+T0Y2CuB/un1lBg9606	rogid:t4PQ2ND+pPVb7QdkoNSpFPNr+SE559292	intact-crc:78009CB30AD5A8E2|rigid:hlK3iuu+1zoyfgZlPVMD9BxN8lk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40151	uniprotkb:P63279	intact:EBI-29152|uniprotkb:D6W0X2|ensemblfungi:YNL218W	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	psi-mi:wrip1_yeast(display_long)|uniprotkb:Maintenance of genome stability protein 1(gene name synonym)|uniprotkb:YNL218W(locus name)|uniprotkb:N1302(orf name)|uniprotkb:MGS1(gene name)|psi-mi:MGS1(display_short)	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11559616|imex:IM-24995-4855	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014181.1|sgd:S000005162|dip:DIP-1638N|ensemblfungi:YNL218W(gene)|ensemblfungi:YNL218W_mRNA(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0017116"(single-stranded DNA helicase activity)|go:"GO:0033567"(DNA replication, Okazaki fragment processing)|go:"GO:0046872"(metal ion binding)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR006642(Zinc finger, Rad18-type putative)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR021886|interpro:IPR027417|interpro:IPR032423|sgd:YNL218W(identity)	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N|entrezgene/locuslink:7329(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:p3Wxu3/I3MK3y5fH85a0FFsg2Qo559292	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	intact-crc:B2FF665A2ACC996E|rigid:F75dw3xBEpoULeIzUTw1/2dCaaU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40151	uniprotkb:O60684	intact:EBI-29152|uniprotkb:D6W0X2|ensemblfungi:YNL218W	intact:EBI-359923|uniprotkb:Q5VVU3|uniprotkb:B2RDC7|ensembl:ENSP00000362728|uniprotkb:D3DPP5	psi-mi:wrip1_yeast(display_long)|uniprotkb:Maintenance of genome stability protein 1(gene name synonym)|uniprotkb:YNL218W(locus name)|uniprotkb:N1302(orf name)|uniprotkb:MGS1(gene name)|psi-mi:MGS1(display_short)	psi-mi:ima7_human(display_long)|uniprotkb:KPNA6(gene name)|psi-mi:KPNA6(display_short)|uniprotkb:IPOA7(gene name synonym)|uniprotkb:Karyopherin subunit alpha-6(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11559607|imex:IM-24995-4854	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014181.1|sgd:S000005162|dip:DIP-1638N|ensemblfungi:YNL218W(gene)|ensemblfungi:YNL218W_mRNA(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0017116"(single-stranded DNA helicase activity)|go:"GO:0033567"(DNA replication, Okazaki fragment processing)|go:"GO:0046872"(metal ion binding)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR006642(Zinc finger, Rad18-type putative)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR021886|interpro:IPR027417|interpro:IPR032423|sgd:YNL218W(identity)	refseq:NP_036448.1|ensembl:ENSG00000025800(gene)|ensembl:ENST00000373625(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0016020"(membrane)|go:"GO:0019079"(viral genome replication)|go:"GO:0030682"(mitigation of host defenses by symbiont)|go:"GO:0043657"(host cell)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060135"(maternal process involved in female pregnancy)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0075506"(entry of viral genome into host nucleus through nuclear pore complex via importin)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:1903902"(positive regulation of viral life cycle)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|mint:O60684|rcsb pdb:4UAD|dip:DIP-27609N|entrezgene/locuslink:23633(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:p3Wxu3/I3MK3y5fH85a0FFsg2Qo559292	rogid:3NsSIcE6BHIqYlvfGRolUKD/5uc9606	intact-crc:2CFE7B4CB3037A66|rigid:V7syCjAy9ACvfvoaFtDSyAjbkwI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12800	uniprotkb:P40185	intact:EBI-717422|uniprotkb:Q12801|uniprotkb:Q9UD77|uniprotkb:A8K5E9|uniprotkb:Q9UD75|ensembl:ENSP00000257915	intact:EBI-11022|ensemblfungi:YIL051C|uniprotkb:D6VVN0	psi-mi:tfcp2_human(display_long)|uniprotkb:Transcription factor LSF(gene name synonym)|uniprotkb:SAA3 enhancer factor(gene name synonym)|uniprotkb:TFCP2(gene name)|psi-mi:TFCP2(display_short)|uniprotkb:LSF(gene name synonym)|uniprotkb:SEF(gene name synonym)	psi-mi:mmf1_yeast(display_long)|uniprotkb:MMF1(gene name)|psi-mi:MMF1(display_short)|uniprotkb:IBM1(gene name synonym)|uniprotkb:Maintenance of mitochondrial function 1(gene name synonym)|uniprotkb:Isoleucine biosynthesis and maintenance of intact mitochondria 1(gene name synonym)|uniprotkb:YIL051C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11559634|imex:IM-24995-4857	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001166923.1|refseq:NP_001166924.1|refseq:NP_005644.2|ensembl:ENSG00000135457(gene)|ensembl:ENST00000257915(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR007604(CP2 transcription factor)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR037599|interpro:IPR041418|mint:Q12800|entrezgene/locuslink:7024(identity)	ensemblfungi:YIL051C(gene)|ensemblfungi:YIL051C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0009097"(isoleucine biosynthetic process)|go:"GO:0019239"(deaminase activity)|go:"GO:0032543"(mitochondrial translation)|go:"GO:1901565"(organonitrogen compound catabolic process)|interpro:IPR006056(YjgF-like protein)|interpro:IPR006175(Endoribonuclease L-PSP)|interpro:IPR019897|interpro:IPR035959|rcsb pdb:3QUW|refseq:NP_012213.3|sgd:S000001313|mint:P40185|dip:DIP-4714N|sgd:YIL051C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:M7mQ08NDYxuawmUEKRgjSdIr+Og9606	rogid:N825kjK9jblhOOg4MZP7RmQXN1M559292	intact-crc:528D5A02389D7A1A|rigid:nuT+IJit7wXV1lpOKf+gK5hVN+I	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O75821	uniprotkb:P40217	intact:EBI-366632|uniprotkb:O14801|uniprotkb:Q969U5|intact:EBI-28974438|ensembl:ENSP00000253108	intact:EBI-8951|ensemblfungi:YMR146C|uniprotkb:D6VZW8	psi-mi:eif3g_human(display_long)|uniprotkb:EIF3G(gene name)|psi-mi:EIF3G(display_short)|uniprotkb:EIF3S4(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 4(gene name synonym)|uniprotkb:eIF-3-delta(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 RNA-binding subunit(gene name synonym)|uniprotkb:eIF3 p44(gene name synonym)|uniprotkb:eIF3 p42(gene name synonym)	psi-mi:eif3i_yeast(display_long)|uniprotkb:TIF34(gene name)|psi-mi:TIF34(display_short)|uniprotkb:YMR146C(locus name)|uniprotkb:YM9375.16C(orf name)|uniprotkb:Eukaryotic translation initiation factor 3 39 kDa subunit(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11559643|imex:IM-24995-4858	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000253108|refseq:NP_003746.2|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0075525"(viral translational termination-reinitiation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR017334(Translation initiation factor 3, RNA-binding subunit)|interpro:IPR024675|interpro:IPR034240|interpro:IPR035979|mint:O75821|rcsb pdb:2CQ0|rcsb pdb:2MJC|rcsb pdb:5K0Y|rcsb pdb:6YBS|rcsb pdb:6ZMW|reactome:R-HSA-156827|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|ensembl:ENSG00000130811(gene)|ensembl:ENST00000253108(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|dip:DIP-31115N|entrezgene/locuslink:8666(identity)	ensemblfungi:YMR146C(gene)|ensemblfungi:YMR146C_mRNA(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0002183"(cytoplasmic translational initiation)|go:"GO:0002188"(translation reinitiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0043614"(multi-eIF complex)|go:"GO:0071541"(eukaryotic translation initiation factor 3 complex, eIF3m)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR027525|interpro:IPR036322|rcsb pdb:3JAP|rcsb pdb:3JAQ|rcsb pdb:3ZWL|rcsb pdb:5A5U|rcsb pdb:6FYX|rcsb pdb:6FYY|rcsb pdb:6GSM|rcsb pdb:6GSN|rcsb pdb:6ZCE|rcsb pdb:6ZU9|reactome:R-SCE-156827|reactome:R-SCE-72649|reactome:R-SCE-72695|reactome:R-SCE-72702|refseq:NP_013866.1|sgd:S000004754|mint:P40217|dip:DIP-2520N|sgd:YMR146C(identity)	-	-	crc64:E6C0D0B275E87622	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:ZHm8Il08Zyb6kFAavZo4tnuUN4g9606	rogid:yiEGZUsT5RdaocsqZq2BUELIsR8559292	intact-crc:46215DE2CDDF623B|rigid:vzNfpj9VStpaFdO/Ylg0KfiZkgA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96BA8	uniprotkb:P40260	intact:EBI-6942903|ensembl:ENSP00000481956|intact:MINT-268046|intact:MINT-8162577|uniprotkb:Q8N2D5|uniprotkb:Q96CP0	intact:EBI-10714|ensemblfungi:YGR121C|uniprotkb:D6VUQ2	psi-mi:cr3l1_human(display_long)|uniprotkb:CREB3L1(gene name)|psi-mi:CREB3L1(display_short)|uniprotkb:OASIS(gene name synonym)|uniprotkb:PSEC0238(orf name)|uniprotkb:Old astrocyte specifically-induced substance(gene name synonym)	psi-mi:mep1_yeast(display_long)|uniprotkb:MEP1(gene name)|psi-mi:MEP1(display_short)|uniprotkb:YGR121C(locus name)|uniprotkb:G6331(orf name)|uniprotkb:AMT1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11559652|imex:IM-24995-4859	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157613(gene)|ensembl:ENST00000621158(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0070278"(extracellular matrix constituent secretion)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029805|mint:Q96BA8|reactome:R-HSA-8874211|refseq:NP_443086.1|entrezgene/locuslink:90993(identity)	ensemblfungi:YGR121C(gene)|ensemblfungi:YGR121C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008519"(ammonium transmembrane transporter activity)|go:"GO:0015696"|go:"GO:0019740"(nitrogen utilization)|interpro:IPR001905(Ammonium transporter)|interpro:IPR018047|interpro:IPR024041|interpro:IPR029020|sgd:S000003353|refseq:NP_011636.3|mint:P40260|dip:DIP-5530N|sgd:YGR121C(identity)	-	comment:mint|function:"Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE"	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:sMWUFmBeBBCO+T0Y2CuB/un1lBg9606	rogid:VnoBl5jhQD24N0SbCLv68HCwl1U559292	intact-crc:CB33E70C019E26FC|rigid:ZKdgQdgjnCX7kncCJGtxbUP2YH8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40302	uniprotkb:O75936	intact:EBI-13955|ensemblfungi:YMR314W|uniprotkb:D6W0E1	intact:EBI-715662|uniprotkb:Q6IBJ2|ensembl:ENSP00000263182|ensembl:ENSP00000433772|ensembl:ENSP00000434918|ensembl:ENSP00000435781|uniprotkb:B2R8L7|uniprotkb:D3DQZ1	psi-mi:psa6_yeast(display_long)|uniprotkb:PRE5(gene name)|psi-mi:PRE5(display_short)|uniprotkb:YMR314W(locus name)|uniprotkb:YM9924.06(orf name)|uniprotkb:Proteasome component PRE5(gene name synonym)|uniprotkb:Macropain subunit PRE5(gene name synonym)|uniprotkb:Proteinase YSCE subunit PRE5(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit PRE5(gene name synonym)	psi-mi:bodg_human(display_long)|uniprotkb:Gamma-butyrobetaine,2-oxoglutarate dioxygenase(gene name synonym)|uniprotkb:Gamma-butyrobetaine hydroxylase(gene name synonym)|uniprotkb:BBOX1(gene name)|psi-mi:BBOX1(display_short)|uniprotkb:BBH(gene name synonym)|uniprotkb:BBOX(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11559681|imex:IM-24995-4862	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:4Y8T|rcsb pdb:4Y8U|rcsb pdb:4Y9Y|rcsb pdb:4Y9Z|rcsb pdb:4YA0|rcsb pdb:4YA1|rcsb pdb:4YA2|rcsb pdb:4YA3|rcsb pdb:4YA4|rcsb pdb:4YA5|rcsb pdb:4Y7X|rcsb pdb:4Y7Y|rcsb pdb:4Y80|rcsb pdb:4Y81|rcsb pdb:4Y82|rcsb pdb:4Y84|rcsb pdb:4Y8G|rcsb pdb:4Y8H|rcsb pdb:4Y8I|rcsb pdb:4Y8J|rcsb pdb:4Y8K|rcsb pdb:4Y8L|rcsb pdb:4Y8M|rcsb pdb:4Y8N|rcsb pdb:4Y8O|rcsb pdb:4Y8P|rcsb pdb:4Y8Q|rcsb pdb:4Y8R|rcsb pdb:4Y8S|rcsb pdb:5FG7|rcsb pdb:5FG9|rcsb pdb:5FGA|rcsb pdb:4YA7|rcsb pdb:4YA9|rcsb pdb:4Z1L|rcsb pdb:5A5B|rcsb pdb:5AHJ|rcsb pdb:5BOU|rcsb pdb:5BXL|rcsb pdb:5BXN|rcsb pdb:5CGF|rcsb pdb:5CGG|rcsb pdb:5CGH|rcsb pdb:5CGI|rcsb pdb:5CZ4|rcsb pdb:5CZ5|rcsb pdb:5CZ6|rcsb pdb:5CZ7|rcsb pdb:5CZ8|rcsb pdb:5CZ9|rcsb pdb:5CZA|rcsb pdb:5D0S|rcsb pdb:5D0T|rcsb pdb:5D0V|rcsb pdb:5D0W|rcsb pdb:5D0X|rcsb pdb:5D0Z|rcsb pdb:5DKI|rcsb pdb:5DKJ|rcsb pdb:5FGD|rcsb pdb:3HYE|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:3MG0|rcsb pdb:3MG4|rcsb pdb:3MG6|rcsb pdb:3MG7|rcsb pdb:3MG8|rcsb pdb:3NZJ|rcsb pdb:3NZW|rcsb pdb:3NZX|rcsb pdb:3OEU|rcsb pdb:3OEV|rcsb pdb:3OKJ|rcsb pdb:3SDI|rcsb pdb:3SDK|rcsb pdb:3SHJ|rcsb pdb:3TDD|rcsb pdb:3UN4|rcsb pdb:3UN8|rcsb pdb:3WXR|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:4EU2|rcsb pdb:4FZC|rcsb pdb:4FZG|rcsb pdb:4G4S|rcsb pdb:4GK7|rcsb pdb:4HNP|rcsb pdb:4HRC|rcsb pdb:4HRD|rcsb pdb:4INR|rcsb pdb:4INT|rcsb pdb:4INU|rcsb pdb:4J70|rcsb pdb:4JSQ|rcsb pdb:4JSU|rcsb pdb:4JT0|rcsb pdb:4LQI|rcsb pdb:4LTC|rcsb pdb:4NNN|rcsb pdb:4NNW|rcsb pdb:4NO1|rcsb pdb:4NO6|rcsb pdb:4NO8|rcsb pdb:4NO9|rcsb pdb:5FGE|rcsb pdb:5FGF|rcsb pdb:5FGG|rcsb pdb:5FGH|rcsb pdb:5FGI|rcsb pdb:5FHS|rcsb pdb:5JHR|rcsb pdb:5JHS|rcsb pdb:5L52|rcsb pdb:5L54|rcsb pdb:5L55|rcsb pdb:5L5A|rcsb pdb:5L5B|rcsb pdb:5L5D|rcsb pdb:5L5E|rcsb pdb:5L5F|rcsb pdb:5L5H|rcsb pdb:5L5I|rcsb pdb:5L5J|rcsb pdb:5L5O|rcsb pdb:5L5P|rcsb pdb:5L5Q|rcsb pdb:5L5R|rcsb pdb:4Q1S|rcsb pdb:4QBY|rcsb pdb:4QLQ|rcsb pdb:4QLS|rcsb pdb:4QLT|rcsb pdb:4QLU|rcsb pdb:4QLV|rcsb pdb:4QUX|rcsb pdb:4QUY|rcsb pdb:4QV0|rcsb pdb:4QV1|rcsb pdb:4QV3|rcsb pdb:4QV4|rcsb pdb:4QV5|rcsb pdb:4QV6|rcsb pdb:4QV7|rcsb pdb:4QV8|rcsb pdb:4QV9|rcsb pdb:4QVL|ensemblfungi:YMR314W(gene)|ensemblfungi:YMR314W_mRNA(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0042175"(nuclear outer membrane-endoplasmic reticulum membrane network)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR035144|rcsb pdb:1FNT|rcsb pdb:1G0U|rcsb pdb:1G65|rcsb pdb:1JD2|rcsb pdb:1RYP|rcsb pdb:1Z7Q|rcsb pdb:2F16|rcsb pdb:2FAK|rcsb pdb:2GPL|rcsb pdb:2ZCY|rcsb pdb:3BDM|rcsb pdb:3D29|rcsb pdb:3DY3|rcsb pdb:3DY4|rcsb pdb:3E47|rcsb pdb:3GPJ|rcsb pdb:3GPT|rcsb pdb:3GPW|rcsb pdb:4QVM|rcsb pdb:4QVN|rcsb pdb:4QVP|rcsb pdb:4QVQ|rcsb pdb:4QVV|rcsb pdb:4QVW|rcsb pdb:4QVY|rcsb pdb:4QW0|rcsb pdb:4QW1|rcsb pdb:4QW3|rcsb pdb:4QW4|rcsb pdb:4QW5|rcsb pdb:4QW6|rcsb pdb:4QW7|rcsb pdb:4QWF|rcsb pdb:4QWG|rcsb pdb:4QWI|rcsb pdb:4QWJ|rcsb pdb:4QWK|rcsb pdb:4QWL|rcsb pdb:4QWR|rcsb pdb:4QWS|rcsb pdb:4QWU|rcsb pdb:4QWX|rcsb pdb:4QXJ|rcsb pdb:4QZ0|rcsb pdb:4QZ1|rcsb pdb:4QZ2|rcsb pdb:4QZ3|rcsb pdb:4QZ4|rcsb pdb:4QZ5|rcsb pdb:4QZ6|rcsb pdb:4QZ7|rcsb pdb:4QZW|rcsb pdb:4QZX|rcsb pdb:4QZZ|rcsb pdb:4R00|rcsb pdb:4R02|rcsb pdb:4R17|rcsb pdb:4R18|rcsb pdb:4RUR|rcsb pdb:4V7O|rcsb pdb:4X6Z|rcsb pdb:4Y69|rcsb pdb:4Y6A|rcsb pdb:4Y6V|rcsb pdb:4Y6Z|rcsb pdb:4Y70|rcsb pdb:4Y74|rcsb pdb:4Y75|rcsb pdb:4Y77|rcsb pdb:4Y78|rcsb pdb:4Y7W|rcsb pdb:5LTT|rcsb pdb:5M2B|rcsb pdb:5MP9|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5NIF|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6G7F|rcsb pdb:6G8M|rcsb pdb:6G8N|rcsb pdb:6GOP|rcsb pdb:6H39|rcsb pdb:6HTB|rcsb pdb:6HTC|rcsb pdb:6HTD|rcsb pdb:6HTP|rcsb pdb:6HTR|rcsb pdb:6HUB|rcsb pdb:6HUC|rcsb pdb:6HUQ|rcsb pdb:6HUU|rcsb pdb:6HUV|rcsb pdb:6HV3|rcsb pdb:6HV4|rcsb pdb:6HV5|rcsb pdb:6HV7|rcsb pdb:6HVA|rcsb pdb:6HVR|rcsb pdb:6HVS|rcsb pdb:6HVT|rcsb pdb:6HVU|rcsb pdb:6HVV|rcsb pdb:5L5S|rcsb pdb:5L5T|rcsb pdb:5L5U|rcsb pdb:5L5V|rcsb pdb:5L5W|rcsb pdb:5L5X|rcsb pdb:5L5Y|rcsb pdb:5L5Z|rcsb pdb:5L60|rcsb pdb:5L61|rcsb pdb:5L62|rcsb pdb:5L63|rcsb pdb:5L64|rcsb pdb:5L65|rcsb pdb:5L66|rcsb pdb:5L67|rcsb pdb:5L68|rcsb pdb:5L69|rcsb pdb:5L6A|rcsb pdb:5L6B|rcsb pdb:5L6C|rcsb pdb:5LAI|rcsb pdb:5LAJ|rcsb pdb:6HVW|rcsb pdb:6HVX|rcsb pdb:6HVY|rcsb pdb:6HW0|rcsb pdb:6HW3|rcsb pdb:6HW4|rcsb pdb:6HW5|rcsb pdb:6HW6|rcsb pdb:6HW7|rcsb pdb:6HW8|rcsb pdb:6HW9|rcsb pdb:6HWA|rcsb pdb:6HWB|rcsb pdb:6HWC|rcsb pdb:6HWD|rcsb pdb:6HWE|rcsb pdb:6HWF|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2X|rcsb pdb:6J30|rcsb pdb:6ZOU|rcsb pdb:6ZP6|rcsb pdb:6ZP8|rcsb pdb:7LS5|rcsb pdb:7LS6|rcsb pdb:7LSX|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|rcsb pdb:6J2Q|refseq:NP_014045.1|sgd:S000004931|mint:P40302|dip:DIP-1528N|sgd:YMR314W(identity)	refseq:NP_003977.1|refseq:XP_005253216.1|refseq:XP_005253217.1|refseq:XP_005253218.1|ensembl:ENSG00000129151(gene)|ensembl:ENST00000263182(transcript)|ensembl:ENST00000525090(transcript)|ensembl:ENST00000528583(transcript)|ensembl:ENST00000529202(transcript)|go:"GO:0005506"(iron ion binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008336"(gamma-butyrobetaine dioxygenase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0045329"(carnitine biosynthetic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR003819(Taurine catabolism dioxygenase TauD/TfdA)|interpro:IPR010376(Protein of unknown function DUF971)|interpro:IPR012775(Gamma-butyrobetaine,2-oxoglutarate dioxygenase)|interpro:IPR038492|interpro:IPR042098|mint:O75936|rcsb pdb:3MS5|rcsb pdb:3N6W|rcsb pdb:3O2G|rcsb pdb:4BG1|rcsb pdb:4BGK|rcsb pdb:4BGM|rcsb pdb:4BHF|rcsb pdb:4BHG|rcsb pdb:4BHI|rcsb pdb:4C5W|rcsb pdb:4C8R|rcsb pdb:4CWD|reactome:R-HSA-71262|refseq:XP_011518704.1|refseq:XP_016873892.1|entrezgene/locuslink:8424(identity)	-	crc64:C43CBCC1C6B9E39E	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:C9GPb0JAklkBz0t/YYqRMNEiQss559292	rogid:oEjzTzRRvj9ygqEj2pca6MxK1Jo9606	intact-crc:0EF1A183CB176B64|rigid:l/M0DjcolNXCiU1n3A7/37FZ5p4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40302	uniprotkb:A9UHW6-2	intact:EBI-13955|ensemblfungi:YMR314W|uniprotkb:D6W0E1	intact:EBI-9118295|ensembl:ENSP00000245551	psi-mi:psa6_yeast(display_long)|uniprotkb:PRE5(gene name)|psi-mi:PRE5(display_short)|uniprotkb:YMR314W(locus name)|uniprotkb:YM9924.06(orf name)|uniprotkb:Proteasome component PRE5(gene name synonym)|uniprotkb:Macropain subunit PRE5(gene name synonym)|uniprotkb:Proteinase YSCE subunit PRE5(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit PRE5(gene name synonym)	psi-mi:a9uhw6-2(display_long)|uniprotkb:MIF4GD(gene name)|psi-mi:MIF4GD(display_short)|uniprotkb:SLIP1(gene name synonym)|uniprotkb:SLBP-interacting protein 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11559661|imex:IM-24995-4860	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:4Y8T|rcsb pdb:4Y8U|rcsb pdb:4Y9Y|rcsb pdb:4Y9Z|rcsb pdb:4YA0|rcsb pdb:4YA1|rcsb pdb:4YA2|rcsb pdb:4YA3|rcsb pdb:4YA4|rcsb pdb:4YA5|rcsb pdb:4Y7X|rcsb pdb:4Y7Y|rcsb pdb:4Y80|rcsb pdb:4Y81|rcsb pdb:4Y82|rcsb pdb:4Y84|rcsb pdb:4Y8G|rcsb pdb:4Y8H|rcsb pdb:4Y8I|rcsb pdb:4Y8J|rcsb pdb:4Y8K|rcsb pdb:4Y8L|rcsb pdb:4Y8M|rcsb pdb:4Y8N|rcsb pdb:4Y8O|rcsb pdb:4Y8P|rcsb pdb:4Y8Q|rcsb pdb:4Y8R|rcsb pdb:4Y8S|rcsb pdb:5FG7|rcsb pdb:5FG9|rcsb pdb:5FGA|rcsb pdb:4YA7|rcsb pdb:4YA9|rcsb pdb:4Z1L|rcsb pdb:5A5B|rcsb pdb:5AHJ|rcsb pdb:5BOU|rcsb pdb:5BXL|rcsb pdb:5BXN|rcsb pdb:5CGF|rcsb pdb:5CGG|rcsb pdb:5CGH|rcsb pdb:5CGI|rcsb pdb:5CZ4|rcsb pdb:5CZ5|rcsb pdb:5CZ6|rcsb pdb:5CZ7|rcsb pdb:5CZ8|rcsb pdb:5CZ9|rcsb pdb:5CZA|rcsb pdb:5D0S|rcsb pdb:5D0T|rcsb pdb:5D0V|rcsb pdb:5D0W|rcsb pdb:5D0X|rcsb pdb:5D0Z|rcsb pdb:5DKI|rcsb pdb:5DKJ|rcsb pdb:5FGD|rcsb pdb:3HYE|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:3MG0|rcsb pdb:3MG4|rcsb pdb:3MG6|rcsb pdb:3MG7|rcsb pdb:3MG8|rcsb pdb:3NZJ|rcsb pdb:3NZW|rcsb pdb:3NZX|rcsb pdb:3OEU|rcsb pdb:3OEV|rcsb pdb:3OKJ|rcsb pdb:3SDI|rcsb pdb:3SDK|rcsb pdb:3SHJ|rcsb pdb:3TDD|rcsb pdb:3UN4|rcsb pdb:3UN8|rcsb pdb:3WXR|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:4EU2|rcsb pdb:4FZC|rcsb pdb:4FZG|rcsb pdb:4G4S|rcsb pdb:4GK7|rcsb pdb:4HNP|rcsb pdb:4HRC|rcsb pdb:4HRD|rcsb pdb:4INR|rcsb pdb:4INT|rcsb pdb:4INU|rcsb pdb:4J70|rcsb pdb:4JSQ|rcsb pdb:4JSU|rcsb pdb:4JT0|rcsb pdb:4LQI|rcsb pdb:4LTC|rcsb pdb:4NNN|rcsb pdb:4NNW|rcsb pdb:4NO1|rcsb pdb:4NO6|rcsb pdb:4NO8|rcsb pdb:4NO9|rcsb pdb:5FGE|rcsb pdb:5FGF|rcsb pdb:5FGG|rcsb pdb:5FGH|rcsb pdb:5FGI|rcsb pdb:5FHS|rcsb pdb:5JHR|rcsb pdb:5JHS|rcsb pdb:5L52|rcsb pdb:5L54|rcsb pdb:5L55|rcsb pdb:5L5A|rcsb pdb:5L5B|rcsb pdb:5L5D|rcsb pdb:5L5E|rcsb pdb:5L5F|rcsb pdb:5L5H|rcsb pdb:5L5I|rcsb pdb:5L5J|rcsb pdb:5L5O|rcsb pdb:5L5P|rcsb pdb:5L5Q|rcsb pdb:5L5R|rcsb pdb:4Q1S|rcsb pdb:4QBY|rcsb pdb:4QLQ|rcsb pdb:4QLS|rcsb pdb:4QLT|rcsb pdb:4QLU|rcsb pdb:4QLV|rcsb pdb:4QUX|rcsb pdb:4QUY|rcsb pdb:4QV0|rcsb pdb:4QV1|rcsb pdb:4QV3|rcsb pdb:4QV4|rcsb pdb:4QV5|rcsb pdb:4QV6|rcsb pdb:4QV7|rcsb pdb:4QV8|rcsb pdb:4QV9|rcsb pdb:4QVL|ensemblfungi:YMR314W(gene)|ensemblfungi:YMR314W_mRNA(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0042175"(nuclear outer membrane-endoplasmic reticulum membrane network)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR035144|rcsb pdb:1FNT|rcsb pdb:1G0U|rcsb pdb:1G65|rcsb pdb:1JD2|rcsb pdb:1RYP|rcsb pdb:1Z7Q|rcsb pdb:2F16|rcsb pdb:2FAK|rcsb pdb:2GPL|rcsb pdb:2ZCY|rcsb pdb:3BDM|rcsb pdb:3D29|rcsb pdb:3DY3|rcsb pdb:3DY4|rcsb pdb:3E47|rcsb pdb:3GPJ|rcsb pdb:3GPT|rcsb pdb:3GPW|rcsb pdb:4QVM|rcsb pdb:4QVN|rcsb pdb:4QVP|rcsb pdb:4QVQ|rcsb pdb:4QVV|rcsb pdb:4QVW|rcsb pdb:4QVY|rcsb pdb:4QW0|rcsb pdb:4QW1|rcsb pdb:4QW3|rcsb pdb:4QW4|rcsb pdb:4QW5|rcsb pdb:4QW6|rcsb pdb:4QW7|rcsb pdb:4QWF|rcsb pdb:4QWG|rcsb pdb:4QWI|rcsb pdb:4QWJ|rcsb pdb:4QWK|rcsb pdb:4QWL|rcsb pdb:4QWR|rcsb pdb:4QWS|rcsb pdb:4QWU|rcsb pdb:4QWX|rcsb pdb:4QXJ|rcsb pdb:4QZ0|rcsb pdb:4QZ1|rcsb pdb:4QZ2|rcsb pdb:4QZ3|rcsb pdb:4QZ4|rcsb pdb:4QZ5|rcsb pdb:4QZ6|rcsb pdb:4QZ7|rcsb pdb:4QZW|rcsb pdb:4QZX|rcsb pdb:4QZZ|rcsb pdb:4R00|rcsb pdb:4R02|rcsb pdb:4R17|rcsb pdb:4R18|rcsb pdb:4RUR|rcsb pdb:4V7O|rcsb pdb:4X6Z|rcsb pdb:4Y69|rcsb pdb:4Y6A|rcsb pdb:4Y6V|rcsb pdb:4Y6Z|rcsb pdb:4Y70|rcsb pdb:4Y74|rcsb pdb:4Y75|rcsb pdb:4Y77|rcsb pdb:4Y78|rcsb pdb:4Y7W|rcsb pdb:5LTT|rcsb pdb:5M2B|rcsb pdb:5MP9|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5NIF|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6G7F|rcsb pdb:6G8M|rcsb pdb:6G8N|rcsb pdb:6GOP|rcsb pdb:6H39|rcsb pdb:6HTB|rcsb pdb:6HTC|rcsb pdb:6HTD|rcsb pdb:6HTP|rcsb pdb:6HTR|rcsb pdb:6HUB|rcsb pdb:6HUC|rcsb pdb:6HUQ|rcsb pdb:6HUU|rcsb pdb:6HUV|rcsb pdb:6HV3|rcsb pdb:6HV4|rcsb pdb:6HV5|rcsb pdb:6HV7|rcsb pdb:6HVA|rcsb pdb:6HVR|rcsb pdb:6HVS|rcsb pdb:6HVT|rcsb pdb:6HVU|rcsb pdb:6HVV|rcsb pdb:5L5S|rcsb pdb:5L5T|rcsb pdb:5L5U|rcsb pdb:5L5V|rcsb pdb:5L5W|rcsb pdb:5L5X|rcsb pdb:5L5Y|rcsb pdb:5L5Z|rcsb pdb:5L60|rcsb pdb:5L61|rcsb pdb:5L62|rcsb pdb:5L63|rcsb pdb:5L64|rcsb pdb:5L65|rcsb pdb:5L66|rcsb pdb:5L67|rcsb pdb:5L68|rcsb pdb:5L69|rcsb pdb:5L6A|rcsb pdb:5L6B|rcsb pdb:5L6C|rcsb pdb:5LAI|rcsb pdb:5LAJ|rcsb pdb:6HVW|rcsb pdb:6HVX|rcsb pdb:6HVY|rcsb pdb:6HW0|rcsb pdb:6HW3|rcsb pdb:6HW4|rcsb pdb:6HW5|rcsb pdb:6HW6|rcsb pdb:6HW7|rcsb pdb:6HW8|rcsb pdb:6HW9|rcsb pdb:6HWA|rcsb pdb:6HWB|rcsb pdb:6HWC|rcsb pdb:6HWD|rcsb pdb:6HWE|rcsb pdb:6HWF|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2X|rcsb pdb:6J30|rcsb pdb:6ZOU|rcsb pdb:6ZP6|rcsb pdb:6ZP8|rcsb pdb:7LS5|rcsb pdb:7LS6|rcsb pdb:7LSX|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|rcsb pdb:6J2Q|refseq:NP_014045.1|sgd:S000004931|mint:P40302|dip:DIP-1528N|sgd:YMR314W(identity)	intact:EBI-373498(isoform-parent)|ensembl:ENSG00000125457(gene)|ensembl:ENST00000245551(transcript)|uniprotkb:A9UHW6-2(isoform-parent)|entrezgene/locuslink:57409(identity)	-	crc64:C43CBCC1C6B9E39E	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:C9GPb0JAklkBz0t/YYqRMNEiQss559292	rogid:XBdXA9tE5Tk5Pn7mO+RIKrlqhEM9606	intact-crc:2D451D95D8FC52D8|rigid:7wBQ45RgYl7SXSUSonM+ak+4HdU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q7Z6G3-2	uniprotkb:P40302	intact:EBI-10172876|ensembl:ENSP00000457354|intact:EBI-14062040	intact:EBI-13955|ensemblfungi:YMR314W|uniprotkb:D6W0E1	psi-mi:q7z6g3-2(display_long)|uniprotkb:EFCBP2(gene name synonym)|uniprotkb:Neuronal calcium-binding protein 2(gene name synonym)|uniprotkb:Synaptotagmin-interacting protein 2(gene name synonym)|uniprotkb:NECAB2(gene name)|psi-mi:NECAB2(display_short)	psi-mi:psa6_yeast(display_long)|uniprotkb:PRE5(gene name)|psi-mi:PRE5(display_short)|uniprotkb:YMR314W(locus name)|uniprotkb:YM9924.06(orf name)|uniprotkb:Proteasome component PRE5(gene name synonym)|uniprotkb:Macropain subunit PRE5(gene name synonym)|uniprotkb:Proteinase YSCE subunit PRE5(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit PRE5(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11559670|imex:IM-24995-4861	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000103154(gene)|ensembl:ENST00000565691(transcript)|uniprotkb:Q7Z6G3-2(isoform-parent)|intact:EBI-950070(isoform-parent)|entrezgene/locuslink:54550(identity)	rcsb pdb:4Y8T|rcsb pdb:4Y8U|rcsb pdb:4Y9Y|rcsb pdb:4Y9Z|rcsb pdb:4YA0|rcsb pdb:4YA1|rcsb pdb:4YA2|rcsb pdb:4YA3|rcsb pdb:4YA4|rcsb pdb:4YA5|rcsb pdb:4Y7X|rcsb pdb:4Y7Y|rcsb pdb:4Y80|rcsb pdb:4Y81|rcsb pdb:4Y82|rcsb pdb:4Y84|rcsb pdb:4Y8G|rcsb pdb:4Y8H|rcsb pdb:4Y8I|rcsb pdb:4Y8J|rcsb pdb:4Y8K|rcsb pdb:4Y8L|rcsb pdb:4Y8M|rcsb pdb:4Y8N|rcsb pdb:4Y8O|rcsb pdb:4Y8P|rcsb pdb:4Y8Q|rcsb pdb:4Y8R|rcsb pdb:4Y8S|rcsb pdb:5FG7|rcsb pdb:5FG9|rcsb pdb:5FGA|rcsb pdb:4YA7|rcsb pdb:4YA9|rcsb pdb:4Z1L|rcsb pdb:5A5B|rcsb pdb:5AHJ|rcsb pdb:5BOU|rcsb pdb:5BXL|rcsb pdb:5BXN|rcsb pdb:5CGF|rcsb pdb:5CGG|rcsb pdb:5CGH|rcsb pdb:5CGI|rcsb pdb:5CZ4|rcsb pdb:5CZ5|rcsb pdb:5CZ6|rcsb pdb:5CZ7|rcsb pdb:5CZ8|rcsb pdb:5CZ9|rcsb pdb:5CZA|rcsb pdb:5D0S|rcsb pdb:5D0T|rcsb pdb:5D0V|rcsb pdb:5D0W|rcsb pdb:5D0X|rcsb pdb:5D0Z|rcsb pdb:5DKI|rcsb pdb:5DKJ|rcsb pdb:5FGD|rcsb pdb:3HYE|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:3MG0|rcsb pdb:3MG4|rcsb pdb:3MG6|rcsb pdb:3MG7|rcsb pdb:3MG8|rcsb pdb:3NZJ|rcsb pdb:3NZW|rcsb pdb:3NZX|rcsb pdb:3OEU|rcsb pdb:3OEV|rcsb pdb:3OKJ|rcsb pdb:3SDI|rcsb pdb:3SDK|rcsb pdb:3SHJ|rcsb pdb:3TDD|rcsb pdb:3UN4|rcsb pdb:3UN8|rcsb pdb:3WXR|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:4EU2|rcsb pdb:4FZC|rcsb pdb:4FZG|rcsb pdb:4G4S|rcsb pdb:4GK7|rcsb pdb:4HNP|rcsb pdb:4HRC|rcsb pdb:4HRD|rcsb pdb:4INR|rcsb pdb:4INT|rcsb pdb:4INU|rcsb pdb:4J70|rcsb pdb:4JSQ|rcsb pdb:4JSU|rcsb pdb:4JT0|rcsb pdb:4LQI|rcsb pdb:4LTC|rcsb pdb:4NNN|rcsb pdb:4NNW|rcsb pdb:4NO1|rcsb pdb:4NO6|rcsb pdb:4NO8|rcsb pdb:4NO9|rcsb pdb:5FGE|rcsb pdb:5FGF|rcsb pdb:5FGG|rcsb pdb:5FGH|rcsb pdb:5FGI|rcsb pdb:5FHS|rcsb pdb:5JHR|rcsb pdb:5JHS|rcsb pdb:5L52|rcsb pdb:5L54|rcsb pdb:5L55|rcsb pdb:5L5A|rcsb pdb:5L5B|rcsb pdb:5L5D|rcsb pdb:5L5E|rcsb pdb:5L5F|rcsb pdb:5L5H|rcsb pdb:5L5I|rcsb pdb:5L5J|rcsb pdb:5L5O|rcsb pdb:5L5P|rcsb pdb:5L5Q|rcsb pdb:5L5R|rcsb pdb:4Q1S|rcsb pdb:4QBY|rcsb pdb:4QLQ|rcsb pdb:4QLS|rcsb pdb:4QLT|rcsb pdb:4QLU|rcsb pdb:4QLV|rcsb pdb:4QUX|rcsb pdb:4QUY|rcsb pdb:4QV0|rcsb pdb:4QV1|rcsb pdb:4QV3|rcsb pdb:4QV4|rcsb pdb:4QV5|rcsb pdb:4QV6|rcsb pdb:4QV7|rcsb pdb:4QV8|rcsb pdb:4QV9|rcsb pdb:4QVL|ensemblfungi:YMR314W(gene)|ensemblfungi:YMR314W_mRNA(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0042175"(nuclear outer membrane-endoplasmic reticulum membrane network)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR035144|rcsb pdb:1FNT|rcsb pdb:1G0U|rcsb pdb:1G65|rcsb pdb:1JD2|rcsb pdb:1RYP|rcsb pdb:1Z7Q|rcsb pdb:2F16|rcsb pdb:2FAK|rcsb pdb:2GPL|rcsb pdb:2ZCY|rcsb pdb:3BDM|rcsb pdb:3D29|rcsb pdb:3DY3|rcsb pdb:3DY4|rcsb pdb:3E47|rcsb pdb:3GPJ|rcsb pdb:3GPT|rcsb pdb:3GPW|rcsb pdb:4QVM|rcsb pdb:4QVN|rcsb pdb:4QVP|rcsb pdb:4QVQ|rcsb pdb:4QVV|rcsb pdb:4QVW|rcsb pdb:4QVY|rcsb pdb:4QW0|rcsb pdb:4QW1|rcsb pdb:4QW3|rcsb pdb:4QW4|rcsb pdb:4QW5|rcsb pdb:4QW6|rcsb pdb:4QW7|rcsb pdb:4QWF|rcsb pdb:4QWG|rcsb pdb:4QWI|rcsb pdb:4QWJ|rcsb pdb:4QWK|rcsb pdb:4QWL|rcsb pdb:4QWR|rcsb pdb:4QWS|rcsb pdb:4QWU|rcsb pdb:4QWX|rcsb pdb:4QXJ|rcsb pdb:4QZ0|rcsb pdb:4QZ1|rcsb pdb:4QZ2|rcsb pdb:4QZ3|rcsb pdb:4QZ4|rcsb pdb:4QZ5|rcsb pdb:4QZ6|rcsb pdb:4QZ7|rcsb pdb:4QZW|rcsb pdb:4QZX|rcsb pdb:4QZZ|rcsb pdb:4R00|rcsb pdb:4R02|rcsb pdb:4R17|rcsb pdb:4R18|rcsb pdb:4RUR|rcsb pdb:4V7O|rcsb pdb:4X6Z|rcsb pdb:4Y69|rcsb pdb:4Y6A|rcsb pdb:4Y6V|rcsb pdb:4Y6Z|rcsb pdb:4Y70|rcsb pdb:4Y74|rcsb pdb:4Y75|rcsb pdb:4Y77|rcsb pdb:4Y78|rcsb pdb:4Y7W|rcsb pdb:5LTT|rcsb pdb:5M2B|rcsb pdb:5MP9|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5NIF|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6G7F|rcsb pdb:6G8M|rcsb pdb:6G8N|rcsb pdb:6GOP|rcsb pdb:6H39|rcsb pdb:6HTB|rcsb pdb:6HTC|rcsb pdb:6HTD|rcsb pdb:6HTP|rcsb pdb:6HTR|rcsb pdb:6HUB|rcsb pdb:6HUC|rcsb pdb:6HUQ|rcsb pdb:6HUU|rcsb pdb:6HUV|rcsb pdb:6HV3|rcsb pdb:6HV4|rcsb pdb:6HV5|rcsb pdb:6HV7|rcsb pdb:6HVA|rcsb pdb:6HVR|rcsb pdb:6HVS|rcsb pdb:6HVT|rcsb pdb:6HVU|rcsb pdb:6HVV|rcsb pdb:5L5S|rcsb pdb:5L5T|rcsb pdb:5L5U|rcsb pdb:5L5V|rcsb pdb:5L5W|rcsb pdb:5L5X|rcsb pdb:5L5Y|rcsb pdb:5L5Z|rcsb pdb:5L60|rcsb pdb:5L61|rcsb pdb:5L62|rcsb pdb:5L63|rcsb pdb:5L64|rcsb pdb:5L65|rcsb pdb:5L66|rcsb pdb:5L67|rcsb pdb:5L68|rcsb pdb:5L69|rcsb pdb:5L6A|rcsb pdb:5L6B|rcsb pdb:5L6C|rcsb pdb:5LAI|rcsb pdb:5LAJ|rcsb pdb:6HVW|rcsb pdb:6HVX|rcsb pdb:6HVY|rcsb pdb:6HW0|rcsb pdb:6HW3|rcsb pdb:6HW4|rcsb pdb:6HW5|rcsb pdb:6HW6|rcsb pdb:6HW7|rcsb pdb:6HW8|rcsb pdb:6HW9|rcsb pdb:6HWA|rcsb pdb:6HWB|rcsb pdb:6HWC|rcsb pdb:6HWD|rcsb pdb:6HWE|rcsb pdb:6HWF|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2X|rcsb pdb:6J30|rcsb pdb:6ZOU|rcsb pdb:6ZP6|rcsb pdb:6ZP8|rcsb pdb:7LS5|rcsb pdb:7LS6|rcsb pdb:7LSX|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|rcsb pdb:6J2Q|refseq:NP_014045.1|sgd:S000004931|mint:P40302|dip:DIP-1528N|sgd:YMR314W(identity)	-	-	crc64:C43CBCC1C6B9E39E	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:4S7oIx6h+mKzV3EPxqcfMNqaNko9606	rogid:C9GPb0JAklkBz0t/YYqRMNEiQss559292	intact-crc:6459949CCA236CF3|rigid:S01jGR6LjAADiaZ9tYOiC9wrNaM	false	sufficient binding region:65-303	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40302	uniprotkb:O95073-2	intact:EBI-13955|ensemblfungi:YMR314W|uniprotkb:D6W0E1	intact:EBI-10696047	psi-mi:psa6_yeast(display_long)|uniprotkb:PRE5(gene name)|psi-mi:PRE5(display_short)|uniprotkb:YMR314W(locus name)|uniprotkb:YM9924.06(orf name)|uniprotkb:Proteasome component PRE5(gene name synonym)|uniprotkb:Macropain subunit PRE5(gene name synonym)|uniprotkb:Proteinase YSCE subunit PRE5(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit PRE5(gene name synonym)	psi-mi:o95073-2(display_long)|uniprotkb:FSBP(gene name)|psi-mi:FSBP(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11559690|imex:IM-24995-4863	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:4Y8T|rcsb pdb:4Y8U|rcsb pdb:4Y9Y|rcsb pdb:4Y9Z|rcsb pdb:4YA0|rcsb pdb:4YA1|rcsb pdb:4YA2|rcsb pdb:4YA3|rcsb pdb:4YA4|rcsb pdb:4YA5|rcsb pdb:4Y7X|rcsb pdb:4Y7Y|rcsb pdb:4Y80|rcsb pdb:4Y81|rcsb pdb:4Y82|rcsb pdb:4Y84|rcsb pdb:4Y8G|rcsb pdb:4Y8H|rcsb pdb:4Y8I|rcsb pdb:4Y8J|rcsb pdb:4Y8K|rcsb pdb:4Y8L|rcsb pdb:4Y8M|rcsb pdb:4Y8N|rcsb pdb:4Y8O|rcsb pdb:4Y8P|rcsb pdb:4Y8Q|rcsb pdb:4Y8R|rcsb pdb:4Y8S|rcsb pdb:5FG7|rcsb pdb:5FG9|rcsb pdb:5FGA|rcsb pdb:4YA7|rcsb pdb:4YA9|rcsb pdb:4Z1L|rcsb pdb:5A5B|rcsb pdb:5AHJ|rcsb pdb:5BOU|rcsb pdb:5BXL|rcsb pdb:5BXN|rcsb pdb:5CGF|rcsb pdb:5CGG|rcsb pdb:5CGH|rcsb pdb:5CGI|rcsb pdb:5CZ4|rcsb pdb:5CZ5|rcsb pdb:5CZ6|rcsb pdb:5CZ7|rcsb pdb:5CZ8|rcsb pdb:5CZ9|rcsb pdb:5CZA|rcsb pdb:5D0S|rcsb pdb:5D0T|rcsb pdb:5D0V|rcsb pdb:5D0W|rcsb pdb:5D0X|rcsb pdb:5D0Z|rcsb pdb:5DKI|rcsb pdb:5DKJ|rcsb pdb:5FGD|rcsb pdb:3HYE|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:3MG0|rcsb pdb:3MG4|rcsb pdb:3MG6|rcsb pdb:3MG7|rcsb pdb:3MG8|rcsb pdb:3NZJ|rcsb pdb:3NZW|rcsb pdb:3NZX|rcsb pdb:3OEU|rcsb pdb:3OEV|rcsb pdb:3OKJ|rcsb pdb:3SDI|rcsb pdb:3SDK|rcsb pdb:3SHJ|rcsb pdb:3TDD|rcsb pdb:3UN4|rcsb pdb:3UN8|rcsb pdb:3WXR|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:4EU2|rcsb pdb:4FZC|rcsb pdb:4FZG|rcsb pdb:4G4S|rcsb pdb:4GK7|rcsb pdb:4HNP|rcsb pdb:4HRC|rcsb pdb:4HRD|rcsb pdb:4INR|rcsb pdb:4INT|rcsb pdb:4INU|rcsb pdb:4J70|rcsb pdb:4JSQ|rcsb pdb:4JSU|rcsb pdb:4JT0|rcsb pdb:4LQI|rcsb pdb:4LTC|rcsb pdb:4NNN|rcsb pdb:4NNW|rcsb pdb:4NO1|rcsb pdb:4NO6|rcsb pdb:4NO8|rcsb pdb:4NO9|rcsb pdb:5FGE|rcsb pdb:5FGF|rcsb pdb:5FGG|rcsb pdb:5FGH|rcsb pdb:5FGI|rcsb pdb:5FHS|rcsb pdb:5JHR|rcsb pdb:5JHS|rcsb pdb:5L52|rcsb pdb:5L54|rcsb pdb:5L55|rcsb pdb:5L5A|rcsb pdb:5L5B|rcsb pdb:5L5D|rcsb pdb:5L5E|rcsb pdb:5L5F|rcsb pdb:5L5H|rcsb pdb:5L5I|rcsb pdb:5L5J|rcsb pdb:5L5O|rcsb pdb:5L5P|rcsb pdb:5L5Q|rcsb pdb:5L5R|rcsb pdb:4Q1S|rcsb pdb:4QBY|rcsb pdb:4QLQ|rcsb pdb:4QLS|rcsb pdb:4QLT|rcsb pdb:4QLU|rcsb pdb:4QLV|rcsb pdb:4QUX|rcsb pdb:4QUY|rcsb pdb:4QV0|rcsb pdb:4QV1|rcsb pdb:4QV3|rcsb pdb:4QV4|rcsb pdb:4QV5|rcsb pdb:4QV6|rcsb pdb:4QV7|rcsb pdb:4QV8|rcsb pdb:4QV9|rcsb pdb:4QVL|ensemblfungi:YMR314W(gene)|ensemblfungi:YMR314W_mRNA(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0042175"(nuclear outer membrane-endoplasmic reticulum membrane network)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR035144|rcsb pdb:1FNT|rcsb pdb:1G0U|rcsb pdb:1G65|rcsb pdb:1JD2|rcsb pdb:1RYP|rcsb pdb:1Z7Q|rcsb pdb:2F16|rcsb pdb:2FAK|rcsb pdb:2GPL|rcsb pdb:2ZCY|rcsb pdb:3BDM|rcsb pdb:3D29|rcsb pdb:3DY3|rcsb pdb:3DY4|rcsb pdb:3E47|rcsb pdb:3GPJ|rcsb pdb:3GPT|rcsb pdb:3GPW|rcsb pdb:4QVM|rcsb pdb:4QVN|rcsb pdb:4QVP|rcsb pdb:4QVQ|rcsb pdb:4QVV|rcsb pdb:4QVW|rcsb pdb:4QVY|rcsb pdb:4QW0|rcsb pdb:4QW1|rcsb pdb:4QW3|rcsb pdb:4QW4|rcsb pdb:4QW5|rcsb pdb:4QW6|rcsb pdb:4QW7|rcsb pdb:4QWF|rcsb pdb:4QWG|rcsb pdb:4QWI|rcsb pdb:4QWJ|rcsb pdb:4QWK|rcsb pdb:4QWL|rcsb pdb:4QWR|rcsb pdb:4QWS|rcsb pdb:4QWU|rcsb pdb:4QWX|rcsb pdb:4QXJ|rcsb pdb:4QZ0|rcsb pdb:4QZ1|rcsb pdb:4QZ2|rcsb pdb:4QZ3|rcsb pdb:4QZ4|rcsb pdb:4QZ5|rcsb pdb:4QZ6|rcsb pdb:4QZ7|rcsb pdb:4QZW|rcsb pdb:4QZX|rcsb pdb:4QZZ|rcsb pdb:4R00|rcsb pdb:4R02|rcsb pdb:4R17|rcsb pdb:4R18|rcsb pdb:4RUR|rcsb pdb:4V7O|rcsb pdb:4X6Z|rcsb pdb:4Y69|rcsb pdb:4Y6A|rcsb pdb:4Y6V|rcsb pdb:4Y6Z|rcsb pdb:4Y70|rcsb pdb:4Y74|rcsb pdb:4Y75|rcsb pdb:4Y77|rcsb pdb:4Y78|rcsb pdb:4Y7W|rcsb pdb:5LTT|rcsb pdb:5M2B|rcsb pdb:5MP9|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5NIF|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6G7F|rcsb pdb:6G8M|rcsb pdb:6G8N|rcsb pdb:6GOP|rcsb pdb:6H39|rcsb pdb:6HTB|rcsb pdb:6HTC|rcsb pdb:6HTD|rcsb pdb:6HTP|rcsb pdb:6HTR|rcsb pdb:6HUB|rcsb pdb:6HUC|rcsb pdb:6HUQ|rcsb pdb:6HUU|rcsb pdb:6HUV|rcsb pdb:6HV3|rcsb pdb:6HV4|rcsb pdb:6HV5|rcsb pdb:6HV7|rcsb pdb:6HVA|rcsb pdb:6HVR|rcsb pdb:6HVS|rcsb pdb:6HVT|rcsb pdb:6HVU|rcsb pdb:6HVV|rcsb pdb:5L5S|rcsb pdb:5L5T|rcsb pdb:5L5U|rcsb pdb:5L5V|rcsb pdb:5L5W|rcsb pdb:5L5X|rcsb pdb:5L5Y|rcsb pdb:5L5Z|rcsb pdb:5L60|rcsb pdb:5L61|rcsb pdb:5L62|rcsb pdb:5L63|rcsb pdb:5L64|rcsb pdb:5L65|rcsb pdb:5L66|rcsb pdb:5L67|rcsb pdb:5L68|rcsb pdb:5L69|rcsb pdb:5L6A|rcsb pdb:5L6B|rcsb pdb:5L6C|rcsb pdb:5LAI|rcsb pdb:5LAJ|rcsb pdb:6HVW|rcsb pdb:6HVX|rcsb pdb:6HVY|rcsb pdb:6HW0|rcsb pdb:6HW3|rcsb pdb:6HW4|rcsb pdb:6HW5|rcsb pdb:6HW6|rcsb pdb:6HW7|rcsb pdb:6HW8|rcsb pdb:6HW9|rcsb pdb:6HWA|rcsb pdb:6HWB|rcsb pdb:6HWC|rcsb pdb:6HWD|rcsb pdb:6HWE|rcsb pdb:6HWF|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2X|rcsb pdb:6J30|rcsb pdb:6ZOU|rcsb pdb:6ZP6|rcsb pdb:6ZP8|rcsb pdb:7LS5|rcsb pdb:7LS6|rcsb pdb:7LSX|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|rcsb pdb:6J2Q|refseq:NP_014045.1|sgd:S000004931|mint:P40302|dip:DIP-1528N|sgd:YMR314W(identity)	intact:EBI-1059030(isoform-parent)|uniprotkb:O95073-2(isoform-parent)|entrezgene/locuslink:25788(identity)	-	crc64:C43CBCC1C6B9E39E	isoform-comment:No experimental confirmation available.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:C9GPb0JAklkBz0t/YYqRMNEiQss559292	rogid:j4ktleFZa7rAjRFENAKAGdAd+Fs9606	intact-crc:83EB23DC0E04CD78|rigid:/4/t9j6pG8UVth1hTqK8+YOMRxc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40302	uniprotkb:Q13137	intact:EBI-13955|ensemblfungi:YMR314W|uniprotkb:D6W0E1	intact:EBI-739580|uniprotkb:B4DDC4|uniprotkb:E7ENK0|uniprotkb:Q53FQ5|uniprotkb:Q53HB5|uniprotkb:Q6IBN9|uniprotkb:Q9BTF7|uniprotkb:B2RBT0|ensembl:ENSP00000258947|uniprotkb:B4E0C0|uniprotkb:E7ETP5|uniprotkb:B4DDT4|uniprotkb:B4DP36|uniprotkb:E9PBE5	psi-mi:psa6_yeast(display_long)|uniprotkb:PRE5(gene name)|psi-mi:PRE5(display_short)|uniprotkb:YMR314W(locus name)|uniprotkb:YM9924.06(orf name)|uniprotkb:Proteasome component PRE5(gene name synonym)|uniprotkb:Macropain subunit PRE5(gene name synonym)|uniprotkb:Proteinase YSCE subunit PRE5(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit PRE5(gene name synonym)	psi-mi:caco2_human(display_long)|uniprotkb:CALCOCO2(gene name)|psi-mi:CALCOCO2(display_short)|uniprotkb:NDP52(gene name synonym)|uniprotkb:Nuclear domain 10 protein NDP52(gene name synonym)|uniprotkb:Antigen nuclear dot 52 kDa protein(gene name synonym)|uniprotkb:Nuclear dot protein 52(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11559708|imex:IM-24995-4865	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:4Y8T|rcsb pdb:4Y8U|rcsb pdb:4Y9Y|rcsb pdb:4Y9Z|rcsb pdb:4YA0|rcsb pdb:4YA1|rcsb pdb:4YA2|rcsb pdb:4YA3|rcsb pdb:4YA4|rcsb pdb:4YA5|rcsb pdb:4Y7X|rcsb pdb:4Y7Y|rcsb pdb:4Y80|rcsb pdb:4Y81|rcsb pdb:4Y82|rcsb pdb:4Y84|rcsb pdb:4Y8G|rcsb pdb:4Y8H|rcsb pdb:4Y8I|rcsb pdb:4Y8J|rcsb pdb:4Y8K|rcsb pdb:4Y8L|rcsb pdb:4Y8M|rcsb pdb:4Y8N|rcsb pdb:4Y8O|rcsb pdb:4Y8P|rcsb pdb:4Y8Q|rcsb pdb:4Y8R|rcsb pdb:4Y8S|rcsb pdb:5FG7|rcsb pdb:5FG9|rcsb pdb:5FGA|rcsb pdb:4YA7|rcsb pdb:4YA9|rcsb pdb:4Z1L|rcsb pdb:5A5B|rcsb pdb:5AHJ|rcsb pdb:5BOU|rcsb pdb:5BXL|rcsb pdb:5BXN|rcsb pdb:5CGF|rcsb pdb:5CGG|rcsb pdb:5CGH|rcsb pdb:5CGI|rcsb pdb:5CZ4|rcsb pdb:5CZ5|rcsb pdb:5CZ6|rcsb pdb:5CZ7|rcsb pdb:5CZ8|rcsb pdb:5CZ9|rcsb pdb:5CZA|rcsb pdb:5D0S|rcsb pdb:5D0T|rcsb pdb:5D0V|rcsb pdb:5D0W|rcsb pdb:5D0X|rcsb pdb:5D0Z|rcsb pdb:5DKI|rcsb pdb:5DKJ|rcsb pdb:5FGD|rcsb pdb:3HYE|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:3MG0|rcsb pdb:3MG4|rcsb pdb:3MG6|rcsb pdb:3MG7|rcsb pdb:3MG8|rcsb pdb:3NZJ|rcsb pdb:3NZW|rcsb pdb:3NZX|rcsb pdb:3OEU|rcsb pdb:3OEV|rcsb pdb:3OKJ|rcsb pdb:3SDI|rcsb pdb:3SDK|rcsb pdb:3SHJ|rcsb pdb:3TDD|rcsb pdb:3UN4|rcsb pdb:3UN8|rcsb pdb:3WXR|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:4EU2|rcsb pdb:4FZC|rcsb pdb:4FZG|rcsb pdb:4G4S|rcsb pdb:4GK7|rcsb pdb:4HNP|rcsb pdb:4HRC|rcsb pdb:4HRD|rcsb pdb:4INR|rcsb pdb:4INT|rcsb pdb:4INU|rcsb pdb:4J70|rcsb pdb:4JSQ|rcsb pdb:4JSU|rcsb pdb:4JT0|rcsb pdb:4LQI|rcsb pdb:4LTC|rcsb pdb:4NNN|rcsb pdb:4NNW|rcsb pdb:4NO1|rcsb pdb:4NO6|rcsb pdb:4NO8|rcsb pdb:4NO9|rcsb pdb:5FGE|rcsb pdb:5FGF|rcsb pdb:5FGG|rcsb pdb:5FGH|rcsb pdb:5FGI|rcsb pdb:5FHS|rcsb pdb:5JHR|rcsb pdb:5JHS|rcsb pdb:5L52|rcsb pdb:5L54|rcsb pdb:5L55|rcsb pdb:5L5A|rcsb pdb:5L5B|rcsb pdb:5L5D|rcsb pdb:5L5E|rcsb pdb:5L5F|rcsb pdb:5L5H|rcsb pdb:5L5I|rcsb pdb:5L5J|rcsb pdb:5L5O|rcsb pdb:5L5P|rcsb pdb:5L5Q|rcsb pdb:5L5R|rcsb pdb:4Q1S|rcsb pdb:4QBY|rcsb pdb:4QLQ|rcsb pdb:4QLS|rcsb pdb:4QLT|rcsb pdb:4QLU|rcsb pdb:4QLV|rcsb pdb:4QUX|rcsb pdb:4QUY|rcsb pdb:4QV0|rcsb pdb:4QV1|rcsb pdb:4QV3|rcsb pdb:4QV4|rcsb pdb:4QV5|rcsb pdb:4QV6|rcsb pdb:4QV7|rcsb pdb:4QV8|rcsb pdb:4QV9|rcsb pdb:4QVL|ensemblfungi:YMR314W(gene)|ensemblfungi:YMR314W_mRNA(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0042175"(nuclear outer membrane-endoplasmic reticulum membrane network)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR035144|rcsb pdb:1FNT|rcsb pdb:1G0U|rcsb pdb:1G65|rcsb pdb:1JD2|rcsb pdb:1RYP|rcsb pdb:1Z7Q|rcsb pdb:2F16|rcsb pdb:2FAK|rcsb pdb:2GPL|rcsb pdb:2ZCY|rcsb pdb:3BDM|rcsb pdb:3D29|rcsb pdb:3DY3|rcsb pdb:3DY4|rcsb pdb:3E47|rcsb pdb:3GPJ|rcsb pdb:3GPT|rcsb pdb:3GPW|rcsb pdb:4QVM|rcsb pdb:4QVN|rcsb pdb:4QVP|rcsb pdb:4QVQ|rcsb pdb:4QVV|rcsb pdb:4QVW|rcsb pdb:4QVY|rcsb pdb:4QW0|rcsb pdb:4QW1|rcsb pdb:4QW3|rcsb pdb:4QW4|rcsb pdb:4QW5|rcsb pdb:4QW6|rcsb pdb:4QW7|rcsb pdb:4QWF|rcsb pdb:4QWG|rcsb pdb:4QWI|rcsb pdb:4QWJ|rcsb pdb:4QWK|rcsb pdb:4QWL|rcsb pdb:4QWR|rcsb pdb:4QWS|rcsb pdb:4QWU|rcsb pdb:4QWX|rcsb pdb:4QXJ|rcsb pdb:4QZ0|rcsb pdb:4QZ1|rcsb pdb:4QZ2|rcsb pdb:4QZ3|rcsb pdb:4QZ4|rcsb pdb:4QZ5|rcsb pdb:4QZ6|rcsb pdb:4QZ7|rcsb pdb:4QZW|rcsb pdb:4QZX|rcsb pdb:4QZZ|rcsb pdb:4R00|rcsb pdb:4R02|rcsb pdb:4R17|rcsb pdb:4R18|rcsb pdb:4RUR|rcsb pdb:4V7O|rcsb pdb:4X6Z|rcsb pdb:4Y69|rcsb pdb:4Y6A|rcsb pdb:4Y6V|rcsb pdb:4Y6Z|rcsb pdb:4Y70|rcsb pdb:4Y74|rcsb pdb:4Y75|rcsb pdb:4Y77|rcsb pdb:4Y78|rcsb pdb:4Y7W|rcsb pdb:5LTT|rcsb pdb:5M2B|rcsb pdb:5MP9|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5NIF|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6G7F|rcsb pdb:6G8M|rcsb pdb:6G8N|rcsb pdb:6GOP|rcsb pdb:6H39|rcsb pdb:6HTB|rcsb pdb:6HTC|rcsb pdb:6HTD|rcsb pdb:6HTP|rcsb pdb:6HTR|rcsb pdb:6HUB|rcsb pdb:6HUC|rcsb pdb:6HUQ|rcsb pdb:6HUU|rcsb pdb:6HUV|rcsb pdb:6HV3|rcsb pdb:6HV4|rcsb pdb:6HV5|rcsb pdb:6HV7|rcsb pdb:6HVA|rcsb pdb:6HVR|rcsb pdb:6HVS|rcsb pdb:6HVT|rcsb pdb:6HVU|rcsb pdb:6HVV|rcsb pdb:5L5S|rcsb pdb:5L5T|rcsb pdb:5L5U|rcsb pdb:5L5V|rcsb pdb:5L5W|rcsb pdb:5L5X|rcsb pdb:5L5Y|rcsb pdb:5L5Z|rcsb pdb:5L60|rcsb pdb:5L61|rcsb pdb:5L62|rcsb pdb:5L63|rcsb pdb:5L64|rcsb pdb:5L65|rcsb pdb:5L66|rcsb pdb:5L67|rcsb pdb:5L68|rcsb pdb:5L69|rcsb pdb:5L6A|rcsb pdb:5L6B|rcsb pdb:5L6C|rcsb pdb:5LAI|rcsb pdb:5LAJ|rcsb pdb:6HVW|rcsb pdb:6HVX|rcsb pdb:6HVY|rcsb pdb:6HW0|rcsb pdb:6HW3|rcsb pdb:6HW4|rcsb pdb:6HW5|rcsb pdb:6HW6|rcsb pdb:6HW7|rcsb pdb:6HW8|rcsb pdb:6HW9|rcsb pdb:6HWA|rcsb pdb:6HWB|rcsb pdb:6HWC|rcsb pdb:6HWD|rcsb pdb:6HWE|rcsb pdb:6HWF|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2X|rcsb pdb:6J30|rcsb pdb:6ZOU|rcsb pdb:6ZP6|rcsb pdb:6ZP8|rcsb pdb:7LS5|rcsb pdb:7LS6|rcsb pdb:7LSX|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|rcsb pdb:6J2Q|refseq:NP_014045.1|sgd:S000004931|mint:P40302|dip:DIP-1528N|sgd:YMR314W(identity)	refseq:NP_001248319.1|refseq:NP_001248320.1|refseq:NP_001248322.1|refseq:NP_005822.1|ensembl:ENSG00000136436(gene)|ensembl:ENST00000258947(transcript)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016032"(viral process)|go:"GO:0016605"(PML body)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0098792"(xenophagy)|go:"GO:1901098"(positive regulation of autophagosome maturation)|interpro:IPR041611|interpro:IPR041641|mint:Q13137|rcsb pdb:2MXP|rcsb pdb:3VVV|rcsb pdb:3VVW|rcsb pdb:4GXL|rcsb pdb:4HAN|rcsb pdb:4XKL|rcsb pdb:5AAQ|rcsb pdb:5Z7A|rcsb pdb:5Z7L|refseq:NP_001248324.1|dip:DIP-57534N|entrezgene/locuslink:10241(identity)	-	crc64:C43CBCC1C6B9E39E	crc64:609B121DA1A9DCB8	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:C9GPb0JAklkBz0t/YYqRMNEiQss559292	rogid:N/GPJUGBK+Dh5Cg+csmafphuo9M9606	intact-crc:94B7875471F3AC11|rigid:ZfDt5eZYjTzVB9Ttb5Mz5Rmtrd4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P14373	uniprotkb:P40302	intact:EBI-719493|uniprotkb:A2BE15|uniprotkb:Q5RJA8|uniprotkb:Q5ST26|uniprotkb:Q6LA73|uniprotkb:Q6NXR9|uniprotkb:Q9BZY6|uniprotkb:Q9UJL3|ensembl:ENSP00000383555|ensembl:ENSP00000392787|ensembl:ENSP00000405229|ensembl:ENSP00000414793|ensembl:ENSP00000366404	intact:EBI-13955|ensemblfungi:YMR314W|uniprotkb:D6W0E1	psi-mi:tri27_human(display_long)|uniprotkb:TRIM27(gene name)|psi-mi:TRIM27(display_short)|uniprotkb:RNF76(gene name synonym)|uniprotkb:RFP(gene name synonym)|uniprotkb:Ret finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 27(gene name synonym)|uniprotkb:RING finger protein 76(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM27(gene name synonym)	psi-mi:psa6_yeast(display_long)|uniprotkb:PRE5(gene name)|psi-mi:PRE5(display_short)|uniprotkb:YMR314W(locus name)|uniprotkb:YM9924.06(orf name)|uniprotkb:Proteasome component PRE5(gene name synonym)|uniprotkb:Macropain subunit PRE5(gene name synonym)|uniprotkb:Proteinase YSCE subunit PRE5(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit PRE5(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11559699|imex:IM-24995-4864	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006501.1|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0090281"(negative regulation of calcium ion import)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR020457|interpro:IPR035791|interpro:IPR043136|mint:P14373|reactome:R-HSA-3232142|reactome:R-HSA-9635465|reactome:R-HSA-8948751|ensembl:ENSG00000204713(gene)|ensembl:ENSG00000215641(gene)|ensembl:ENSG00000229006(gene)|ensembl:ENSG00000234495(gene)|ensembl:ENSG00000237071(gene)|ensembl:ENST00000377199(transcript)|ensembl:ENST00000400720(transcript)|ensembl:ENST00000431123(transcript)|ensembl:ENST00000435528(transcript)|ensembl:ENST00000437160(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001650"(fibrillar center)|go:"GO:0002820"(negative regulation of adaptive immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|entrezgene/locuslink:5987(identity)	rcsb pdb:4Y8T|rcsb pdb:4Y8U|rcsb pdb:4Y9Y|rcsb pdb:4Y9Z|rcsb pdb:4YA0|rcsb pdb:4YA1|rcsb pdb:4YA2|rcsb pdb:4YA3|rcsb pdb:4YA4|rcsb pdb:4YA5|rcsb pdb:4Y7X|rcsb pdb:4Y7Y|rcsb pdb:4Y80|rcsb pdb:4Y81|rcsb pdb:4Y82|rcsb pdb:4Y84|rcsb pdb:4Y8G|rcsb pdb:4Y8H|rcsb pdb:4Y8I|rcsb pdb:4Y8J|rcsb pdb:4Y8K|rcsb pdb:4Y8L|rcsb pdb:4Y8M|rcsb pdb:4Y8N|rcsb pdb:4Y8O|rcsb pdb:4Y8P|rcsb pdb:4Y8Q|rcsb pdb:4Y8R|rcsb pdb:4Y8S|rcsb pdb:5FG7|rcsb pdb:5FG9|rcsb pdb:5FGA|rcsb pdb:4YA7|rcsb pdb:4YA9|rcsb pdb:4Z1L|rcsb pdb:5A5B|rcsb pdb:5AHJ|rcsb pdb:5BOU|rcsb pdb:5BXL|rcsb pdb:5BXN|rcsb pdb:5CGF|rcsb pdb:5CGG|rcsb pdb:5CGH|rcsb pdb:5CGI|rcsb pdb:5CZ4|rcsb pdb:5CZ5|rcsb pdb:5CZ6|rcsb pdb:5CZ7|rcsb pdb:5CZ8|rcsb pdb:5CZ9|rcsb pdb:5CZA|rcsb pdb:5D0S|rcsb pdb:5D0T|rcsb pdb:5D0V|rcsb pdb:5D0W|rcsb pdb:5D0X|rcsb pdb:5D0Z|rcsb pdb:5DKI|rcsb pdb:5DKJ|rcsb pdb:5FGD|rcsb pdb:3HYE|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:3MG0|rcsb pdb:3MG4|rcsb pdb:3MG6|rcsb pdb:3MG7|rcsb pdb:3MG8|rcsb pdb:3NZJ|rcsb pdb:3NZW|rcsb pdb:3NZX|rcsb pdb:3OEU|rcsb pdb:3OEV|rcsb pdb:3OKJ|rcsb pdb:3SDI|rcsb pdb:3SDK|rcsb pdb:3SHJ|rcsb pdb:3TDD|rcsb pdb:3UN4|rcsb pdb:3UN8|rcsb pdb:3WXR|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:4EU2|rcsb pdb:4FZC|rcsb pdb:4FZG|rcsb pdb:4G4S|rcsb pdb:4GK7|rcsb pdb:4HNP|rcsb pdb:4HRC|rcsb pdb:4HRD|rcsb pdb:4INR|rcsb pdb:4INT|rcsb pdb:4INU|rcsb pdb:4J70|rcsb pdb:4JSQ|rcsb pdb:4JSU|rcsb pdb:4JT0|rcsb pdb:4LQI|rcsb pdb:4LTC|rcsb pdb:4NNN|rcsb pdb:4NNW|rcsb pdb:4NO1|rcsb pdb:4NO6|rcsb pdb:4NO8|rcsb pdb:4NO9|rcsb pdb:5FGE|rcsb pdb:5FGF|rcsb pdb:5FGG|rcsb pdb:5FGH|rcsb pdb:5FGI|rcsb pdb:5FHS|rcsb pdb:5JHR|rcsb pdb:5JHS|rcsb pdb:5L52|rcsb pdb:5L54|rcsb pdb:5L55|rcsb pdb:5L5A|rcsb pdb:5L5B|rcsb pdb:5L5D|rcsb pdb:5L5E|rcsb pdb:5L5F|rcsb pdb:5L5H|rcsb pdb:5L5I|rcsb pdb:5L5J|rcsb pdb:5L5O|rcsb pdb:5L5P|rcsb pdb:5L5Q|rcsb pdb:5L5R|rcsb pdb:4Q1S|rcsb pdb:4QBY|rcsb pdb:4QLQ|rcsb pdb:4QLS|rcsb pdb:4QLT|rcsb pdb:4QLU|rcsb pdb:4QLV|rcsb pdb:4QUX|rcsb pdb:4QUY|rcsb pdb:4QV0|rcsb pdb:4QV1|rcsb pdb:4QV3|rcsb pdb:4QV4|rcsb pdb:4QV5|rcsb pdb:4QV6|rcsb pdb:4QV7|rcsb pdb:4QV8|rcsb pdb:4QV9|rcsb pdb:4QVL|ensemblfungi:YMR314W(gene)|ensemblfungi:YMR314W_mRNA(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0042175"(nuclear outer membrane-endoplasmic reticulum membrane network)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR035144|rcsb pdb:1FNT|rcsb pdb:1G0U|rcsb pdb:1G65|rcsb pdb:1JD2|rcsb pdb:1RYP|rcsb pdb:1Z7Q|rcsb pdb:2F16|rcsb pdb:2FAK|rcsb pdb:2GPL|rcsb pdb:2ZCY|rcsb pdb:3BDM|rcsb pdb:3D29|rcsb pdb:3DY3|rcsb pdb:3DY4|rcsb pdb:3E47|rcsb pdb:3GPJ|rcsb pdb:3GPT|rcsb pdb:3GPW|rcsb pdb:4QVM|rcsb pdb:4QVN|rcsb pdb:4QVP|rcsb pdb:4QVQ|rcsb pdb:4QVV|rcsb pdb:4QVW|rcsb pdb:4QVY|rcsb pdb:4QW0|rcsb pdb:4QW1|rcsb pdb:4QW3|rcsb pdb:4QW4|rcsb pdb:4QW5|rcsb pdb:4QW6|rcsb pdb:4QW7|rcsb pdb:4QWF|rcsb pdb:4QWG|rcsb pdb:4QWI|rcsb pdb:4QWJ|rcsb pdb:4QWK|rcsb pdb:4QWL|rcsb pdb:4QWR|rcsb pdb:4QWS|rcsb pdb:4QWU|rcsb pdb:4QWX|rcsb pdb:4QXJ|rcsb pdb:4QZ0|rcsb pdb:4QZ1|rcsb pdb:4QZ2|rcsb pdb:4QZ3|rcsb pdb:4QZ4|rcsb pdb:4QZ5|rcsb pdb:4QZ6|rcsb pdb:4QZ7|rcsb pdb:4QZW|rcsb pdb:4QZX|rcsb pdb:4QZZ|rcsb pdb:4R00|rcsb pdb:4R02|rcsb pdb:4R17|rcsb pdb:4R18|rcsb pdb:4RUR|rcsb pdb:4V7O|rcsb pdb:4X6Z|rcsb pdb:4Y69|rcsb pdb:4Y6A|rcsb pdb:4Y6V|rcsb pdb:4Y6Z|rcsb pdb:4Y70|rcsb pdb:4Y74|rcsb pdb:4Y75|rcsb pdb:4Y77|rcsb pdb:4Y78|rcsb pdb:4Y7W|rcsb pdb:5LTT|rcsb pdb:5M2B|rcsb pdb:5MP9|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5NIF|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6G7F|rcsb pdb:6G8M|rcsb pdb:6G8N|rcsb pdb:6GOP|rcsb pdb:6H39|rcsb pdb:6HTB|rcsb pdb:6HTC|rcsb pdb:6HTD|rcsb pdb:6HTP|rcsb pdb:6HTR|rcsb pdb:6HUB|rcsb pdb:6HUC|rcsb pdb:6HUQ|rcsb pdb:6HUU|rcsb pdb:6HUV|rcsb pdb:6HV3|rcsb pdb:6HV4|rcsb pdb:6HV5|rcsb pdb:6HV7|rcsb pdb:6HVA|rcsb pdb:6HVR|rcsb pdb:6HVS|rcsb pdb:6HVT|rcsb pdb:6HVU|rcsb pdb:6HVV|rcsb pdb:5L5S|rcsb pdb:5L5T|rcsb pdb:5L5U|rcsb pdb:5L5V|rcsb pdb:5L5W|rcsb pdb:5L5X|rcsb pdb:5L5Y|rcsb pdb:5L5Z|rcsb pdb:5L60|rcsb pdb:5L61|rcsb pdb:5L62|rcsb pdb:5L63|rcsb pdb:5L64|rcsb pdb:5L65|rcsb pdb:5L66|rcsb pdb:5L67|rcsb pdb:5L68|rcsb pdb:5L69|rcsb pdb:5L6A|rcsb pdb:5L6B|rcsb pdb:5L6C|rcsb pdb:5LAI|rcsb pdb:5LAJ|rcsb pdb:6HVW|rcsb pdb:6HVX|rcsb pdb:6HVY|rcsb pdb:6HW0|rcsb pdb:6HW3|rcsb pdb:6HW4|rcsb pdb:6HW5|rcsb pdb:6HW6|rcsb pdb:6HW7|rcsb pdb:6HW8|rcsb pdb:6HW9|rcsb pdb:6HWA|rcsb pdb:6HWB|rcsb pdb:6HWC|rcsb pdb:6HWD|rcsb pdb:6HWE|rcsb pdb:6HWF|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2X|rcsb pdb:6J30|rcsb pdb:6ZOU|rcsb pdb:6ZP6|rcsb pdb:6ZP8|rcsb pdb:7LS5|rcsb pdb:7LS6|rcsb pdb:7LSX|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|rcsb pdb:6J2Q|refseq:NP_014045.1|sgd:S000004931|mint:P40302|dip:DIP-1528N|sgd:YMR314W(identity)	-	-	crc64:C43CBCC1C6B9E39E	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:dsfH5OUghD8KSaTz1SFw9OYVTK49606	rogid:C9GPb0JAklkBz0t/YYqRMNEiQss559292	intact-crc:1BED4E93E7F730DC|rigid:NWGPMzOW08lVjEjcmDD50hI80bY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q14566	uniprotkb:P40302	intact:EBI-374900|uniprotkb:Q13504|uniprotkb:Q99859|uniprotkb:B2R6H2|ensembl:ENSP00000264156	intact:EBI-13955|ensemblfungi:YMR314W|uniprotkb:D6W0E1	psi-mi:mcm6_human(display_long)|uniprotkb:MCM6(gene name)|psi-mi:MCM6(display_short)|uniprotkb:p105MCM(gene name synonym)	psi-mi:psa6_yeast(display_long)|uniprotkb:PRE5(gene name)|psi-mi:PRE5(display_short)|uniprotkb:YMR314W(locus name)|uniprotkb:YM9924.06(orf name)|uniprotkb:Proteasome component PRE5(gene name synonym)|uniprotkb:Macropain subunit PRE5(gene name synonym)|uniprotkb:Proteinase YSCE subunit PRE5(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit PRE5(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11559717|imex:IM-24995-4866	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000264156(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0042555"(MCM complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902969"(mitotic DNA replication)|ensembl:ENSG00000076003(gene)|reactome:R-HSA-68962|reactome:R-HSA-69052|interpro:IPR008049(MCM protein 6)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041024|interpro:IPR041562|interpro:IPR001208(MCM)|mint:Q14566|rcsb pdb:2KLQ|rcsb pdb:2LE8|rcsb pdb:6XTX|rcsb pdb:6XTY|reactome:R-HSA-176187|reactome:R-HSA-176974|reactome:R-HSA-68867|reactome:R-HSA-68949|refseq:NP_005906.2|dip:DIP-31727N|entrezgene/locuslink:4175(identity)	rcsb pdb:4Y8T|rcsb pdb:4Y8U|rcsb pdb:4Y9Y|rcsb pdb:4Y9Z|rcsb pdb:4YA0|rcsb pdb:4YA1|rcsb pdb:4YA2|rcsb pdb:4YA3|rcsb pdb:4YA4|rcsb pdb:4YA5|rcsb pdb:4Y7X|rcsb pdb:4Y7Y|rcsb pdb:4Y80|rcsb pdb:4Y81|rcsb pdb:4Y82|rcsb pdb:4Y84|rcsb pdb:4Y8G|rcsb pdb:4Y8H|rcsb pdb:4Y8I|rcsb pdb:4Y8J|rcsb pdb:4Y8K|rcsb pdb:4Y8L|rcsb pdb:4Y8M|rcsb pdb:4Y8N|rcsb pdb:4Y8O|rcsb pdb:4Y8P|rcsb pdb:4Y8Q|rcsb pdb:4Y8R|rcsb pdb:4Y8S|rcsb pdb:5FG7|rcsb pdb:5FG9|rcsb pdb:5FGA|rcsb pdb:4YA7|rcsb pdb:4YA9|rcsb pdb:4Z1L|rcsb pdb:5A5B|rcsb pdb:5AHJ|rcsb pdb:5BOU|rcsb pdb:5BXL|rcsb pdb:5BXN|rcsb pdb:5CGF|rcsb pdb:5CGG|rcsb pdb:5CGH|rcsb pdb:5CGI|rcsb pdb:5CZ4|rcsb pdb:5CZ5|rcsb pdb:5CZ6|rcsb pdb:5CZ7|rcsb pdb:5CZ8|rcsb pdb:5CZ9|rcsb pdb:5CZA|rcsb pdb:5D0S|rcsb pdb:5D0T|rcsb pdb:5D0V|rcsb pdb:5D0W|rcsb pdb:5D0X|rcsb pdb:5D0Z|rcsb pdb:5DKI|rcsb pdb:5DKJ|rcsb pdb:5FGD|rcsb pdb:3HYE|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:3MG0|rcsb pdb:3MG4|rcsb pdb:3MG6|rcsb pdb:3MG7|rcsb pdb:3MG8|rcsb pdb:3NZJ|rcsb pdb:3NZW|rcsb pdb:3NZX|rcsb pdb:3OEU|rcsb pdb:3OEV|rcsb pdb:3OKJ|rcsb pdb:3SDI|rcsb pdb:3SDK|rcsb pdb:3SHJ|rcsb pdb:3TDD|rcsb pdb:3UN4|rcsb pdb:3UN8|rcsb pdb:3WXR|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:4EU2|rcsb pdb:4FZC|rcsb pdb:4FZG|rcsb pdb:4G4S|rcsb pdb:4GK7|rcsb pdb:4HNP|rcsb pdb:4HRC|rcsb pdb:4HRD|rcsb pdb:4INR|rcsb pdb:4INT|rcsb pdb:4INU|rcsb pdb:4J70|rcsb pdb:4JSQ|rcsb pdb:4JSU|rcsb pdb:4JT0|rcsb pdb:4LQI|rcsb pdb:4LTC|rcsb pdb:4NNN|rcsb pdb:4NNW|rcsb pdb:4NO1|rcsb pdb:4NO6|rcsb pdb:4NO8|rcsb pdb:4NO9|rcsb pdb:5FGE|rcsb pdb:5FGF|rcsb pdb:5FGG|rcsb pdb:5FGH|rcsb pdb:5FGI|rcsb pdb:5FHS|rcsb pdb:5JHR|rcsb pdb:5JHS|rcsb pdb:5L52|rcsb pdb:5L54|rcsb pdb:5L55|rcsb pdb:5L5A|rcsb pdb:5L5B|rcsb pdb:5L5D|rcsb pdb:5L5E|rcsb pdb:5L5F|rcsb pdb:5L5H|rcsb pdb:5L5I|rcsb pdb:5L5J|rcsb pdb:5L5O|rcsb pdb:5L5P|rcsb pdb:5L5Q|rcsb pdb:5L5R|rcsb pdb:4Q1S|rcsb pdb:4QBY|rcsb pdb:4QLQ|rcsb pdb:4QLS|rcsb pdb:4QLT|rcsb pdb:4QLU|rcsb pdb:4QLV|rcsb pdb:4QUX|rcsb pdb:4QUY|rcsb pdb:4QV0|rcsb pdb:4QV1|rcsb pdb:4QV3|rcsb pdb:4QV4|rcsb pdb:4QV5|rcsb pdb:4QV6|rcsb pdb:4QV7|rcsb pdb:4QV8|rcsb pdb:4QV9|rcsb pdb:4QVL|ensemblfungi:YMR314W(gene)|ensemblfungi:YMR314W_mRNA(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0042175"(nuclear outer membrane-endoplasmic reticulum membrane network)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR035144|rcsb pdb:1FNT|rcsb pdb:1G0U|rcsb pdb:1G65|rcsb pdb:1JD2|rcsb pdb:1RYP|rcsb pdb:1Z7Q|rcsb pdb:2F16|rcsb pdb:2FAK|rcsb pdb:2GPL|rcsb pdb:2ZCY|rcsb pdb:3BDM|rcsb pdb:3D29|rcsb pdb:3DY3|rcsb pdb:3DY4|rcsb pdb:3E47|rcsb pdb:3GPJ|rcsb pdb:3GPT|rcsb pdb:3GPW|rcsb pdb:4QVM|rcsb pdb:4QVN|rcsb pdb:4QVP|rcsb pdb:4QVQ|rcsb pdb:4QVV|rcsb pdb:4QVW|rcsb pdb:4QVY|rcsb pdb:4QW0|rcsb pdb:4QW1|rcsb pdb:4QW3|rcsb pdb:4QW4|rcsb pdb:4QW5|rcsb pdb:4QW6|rcsb pdb:4QW7|rcsb pdb:4QWF|rcsb pdb:4QWG|rcsb pdb:4QWI|rcsb pdb:4QWJ|rcsb pdb:4QWK|rcsb pdb:4QWL|rcsb pdb:4QWR|rcsb pdb:4QWS|rcsb pdb:4QWU|rcsb pdb:4QWX|rcsb pdb:4QXJ|rcsb pdb:4QZ0|rcsb pdb:4QZ1|rcsb pdb:4QZ2|rcsb pdb:4QZ3|rcsb pdb:4QZ4|rcsb pdb:4QZ5|rcsb pdb:4QZ6|rcsb pdb:4QZ7|rcsb pdb:4QZW|rcsb pdb:4QZX|rcsb pdb:4QZZ|rcsb pdb:4R00|rcsb pdb:4R02|rcsb pdb:4R17|rcsb pdb:4R18|rcsb pdb:4RUR|rcsb pdb:4V7O|rcsb pdb:4X6Z|rcsb pdb:4Y69|rcsb pdb:4Y6A|rcsb pdb:4Y6V|rcsb pdb:4Y6Z|rcsb pdb:4Y70|rcsb pdb:4Y74|rcsb pdb:4Y75|rcsb pdb:4Y77|rcsb pdb:4Y78|rcsb pdb:4Y7W|rcsb pdb:5LTT|rcsb pdb:5M2B|rcsb pdb:5MP9|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5NIF|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6G7F|rcsb pdb:6G8M|rcsb pdb:6G8N|rcsb pdb:6GOP|rcsb pdb:6H39|rcsb pdb:6HTB|rcsb pdb:6HTC|rcsb pdb:6HTD|rcsb pdb:6HTP|rcsb pdb:6HTR|rcsb pdb:6HUB|rcsb pdb:6HUC|rcsb pdb:6HUQ|rcsb pdb:6HUU|rcsb pdb:6HUV|rcsb pdb:6HV3|rcsb pdb:6HV4|rcsb pdb:6HV5|rcsb pdb:6HV7|rcsb pdb:6HVA|rcsb pdb:6HVR|rcsb pdb:6HVS|rcsb pdb:6HVT|rcsb pdb:6HVU|rcsb pdb:6HVV|rcsb pdb:5L5S|rcsb pdb:5L5T|rcsb pdb:5L5U|rcsb pdb:5L5V|rcsb pdb:5L5W|rcsb pdb:5L5X|rcsb pdb:5L5Y|rcsb pdb:5L5Z|rcsb pdb:5L60|rcsb pdb:5L61|rcsb pdb:5L62|rcsb pdb:5L63|rcsb pdb:5L64|rcsb pdb:5L65|rcsb pdb:5L66|rcsb pdb:5L67|rcsb pdb:5L68|rcsb pdb:5L69|rcsb pdb:5L6A|rcsb pdb:5L6B|rcsb pdb:5L6C|rcsb pdb:5LAI|rcsb pdb:5LAJ|rcsb pdb:6HVW|rcsb pdb:6HVX|rcsb pdb:6HVY|rcsb pdb:6HW0|rcsb pdb:6HW3|rcsb pdb:6HW4|rcsb pdb:6HW5|rcsb pdb:6HW6|rcsb pdb:6HW7|rcsb pdb:6HW8|rcsb pdb:6HW9|rcsb pdb:6HWA|rcsb pdb:6HWB|rcsb pdb:6HWC|rcsb pdb:6HWD|rcsb pdb:6HWE|rcsb pdb:6HWF|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2X|rcsb pdb:6J30|rcsb pdb:6ZOU|rcsb pdb:6ZP6|rcsb pdb:6ZP8|rcsb pdb:7LS5|rcsb pdb:7LS6|rcsb pdb:7LSX|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|rcsb pdb:6J2Q|refseq:NP_014045.1|sgd:S000004931|mint:P40302|dip:DIP-1528N|sgd:YMR314W(identity)	-	-	crc64:C43CBCC1C6B9E39E	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:gVpEwgfSwwxvP2T2CvCzIukthY49606	rogid:C9GPb0JAklkBz0t/YYqRMNEiQss559292	intact-crc:54729F58594BBFF3|rigid:ka1v5tXFyE92Gheko7mHscWzz+U	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q5JR59-3	uniprotkb:P40302	intact:EBI-11522433|ensembl:ENSP00000370186	intact:EBI-13955|ensemblfungi:YMR314W|uniprotkb:D6W0E1	psi-mi:q5jr59-3(display_long)|uniprotkb:MTUS2(gene name)|psi-mi:MTUS2(display_short)|uniprotkb:CAZIP(gene name synonym)|uniprotkb:Cardiac zipper protein(gene name synonym)|uniprotkb:KIAA0774(gene name synonym)|uniprotkb:Microtubule plus-end tracking protein TIP150(gene name synonym)|uniprotkb:TIP150(gene name synonym)	psi-mi:psa6_yeast(display_long)|uniprotkb:PRE5(gene name)|psi-mi:PRE5(display_short)|uniprotkb:YMR314W(locus name)|uniprotkb:YM9924.06(orf name)|uniprotkb:Proteasome component PRE5(gene name synonym)|uniprotkb:Macropain subunit PRE5(gene name synonym)|uniprotkb:Proteinase YSCE subunit PRE5(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit PRE5(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11559726|imex:IM-24995-4867	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000132938(gene)|ensembl:ENST00000380808(transcript)|intact:EBI-742948(isoform-parent)|uniprotkb:Q5JR59-3(isoform-parent)|entrezgene/locuslink:23281(identity)	rcsb pdb:4Y8T|rcsb pdb:4Y8U|rcsb pdb:4Y9Y|rcsb pdb:4Y9Z|rcsb pdb:4YA0|rcsb pdb:4YA1|rcsb pdb:4YA2|rcsb pdb:4YA3|rcsb pdb:4YA4|rcsb pdb:4YA5|rcsb pdb:4Y7X|rcsb pdb:4Y7Y|rcsb pdb:4Y80|rcsb pdb:4Y81|rcsb pdb:4Y82|rcsb pdb:4Y84|rcsb pdb:4Y8G|rcsb pdb:4Y8H|rcsb pdb:4Y8I|rcsb pdb:4Y8J|rcsb pdb:4Y8K|rcsb pdb:4Y8L|rcsb pdb:4Y8M|rcsb pdb:4Y8N|rcsb pdb:4Y8O|rcsb pdb:4Y8P|rcsb pdb:4Y8Q|rcsb pdb:4Y8R|rcsb pdb:4Y8S|rcsb pdb:5FG7|rcsb pdb:5FG9|rcsb pdb:5FGA|rcsb pdb:4YA7|rcsb pdb:4YA9|rcsb pdb:4Z1L|rcsb pdb:5A5B|rcsb pdb:5AHJ|rcsb pdb:5BOU|rcsb pdb:5BXL|rcsb pdb:5BXN|rcsb pdb:5CGF|rcsb pdb:5CGG|rcsb pdb:5CGH|rcsb pdb:5CGI|rcsb pdb:5CZ4|rcsb pdb:5CZ5|rcsb pdb:5CZ6|rcsb pdb:5CZ7|rcsb pdb:5CZ8|rcsb pdb:5CZ9|rcsb pdb:5CZA|rcsb pdb:5D0S|rcsb pdb:5D0T|rcsb pdb:5D0V|rcsb pdb:5D0W|rcsb pdb:5D0X|rcsb pdb:5D0Z|rcsb pdb:5DKI|rcsb pdb:5DKJ|rcsb pdb:5FGD|rcsb pdb:3HYE|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:3MG0|rcsb pdb:3MG4|rcsb pdb:3MG6|rcsb pdb:3MG7|rcsb pdb:3MG8|rcsb pdb:3NZJ|rcsb pdb:3NZW|rcsb pdb:3NZX|rcsb pdb:3OEU|rcsb pdb:3OEV|rcsb pdb:3OKJ|rcsb pdb:3SDI|rcsb pdb:3SDK|rcsb pdb:3SHJ|rcsb pdb:3TDD|rcsb pdb:3UN4|rcsb pdb:3UN8|rcsb pdb:3WXR|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:4EU2|rcsb pdb:4FZC|rcsb pdb:4FZG|rcsb pdb:4G4S|rcsb pdb:4GK7|rcsb pdb:4HNP|rcsb pdb:4HRC|rcsb pdb:4HRD|rcsb pdb:4INR|rcsb pdb:4INT|rcsb pdb:4INU|rcsb pdb:4J70|rcsb pdb:4JSQ|rcsb pdb:4JSU|rcsb pdb:4JT0|rcsb pdb:4LQI|rcsb pdb:4LTC|rcsb pdb:4NNN|rcsb pdb:4NNW|rcsb pdb:4NO1|rcsb pdb:4NO6|rcsb pdb:4NO8|rcsb pdb:4NO9|rcsb pdb:5FGE|rcsb pdb:5FGF|rcsb pdb:5FGG|rcsb pdb:5FGH|rcsb pdb:5FGI|rcsb pdb:5FHS|rcsb pdb:5JHR|rcsb pdb:5JHS|rcsb pdb:5L52|rcsb pdb:5L54|rcsb pdb:5L55|rcsb pdb:5L5A|rcsb pdb:5L5B|rcsb pdb:5L5D|rcsb pdb:5L5E|rcsb pdb:5L5F|rcsb pdb:5L5H|rcsb pdb:5L5I|rcsb pdb:5L5J|rcsb pdb:5L5O|rcsb pdb:5L5P|rcsb pdb:5L5Q|rcsb pdb:5L5R|rcsb pdb:4Q1S|rcsb pdb:4QBY|rcsb pdb:4QLQ|rcsb pdb:4QLS|rcsb pdb:4QLT|rcsb pdb:4QLU|rcsb pdb:4QLV|rcsb pdb:4QUX|rcsb pdb:4QUY|rcsb pdb:4QV0|rcsb pdb:4QV1|rcsb pdb:4QV3|rcsb pdb:4QV4|rcsb pdb:4QV5|rcsb pdb:4QV6|rcsb pdb:4QV7|rcsb pdb:4QV8|rcsb pdb:4QV9|rcsb pdb:4QVL|ensemblfungi:YMR314W(gene)|ensemblfungi:YMR314W_mRNA(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0042175"(nuclear outer membrane-endoplasmic reticulum membrane network)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR035144|rcsb pdb:1FNT|rcsb pdb:1G0U|rcsb pdb:1G65|rcsb pdb:1JD2|rcsb pdb:1RYP|rcsb pdb:1Z7Q|rcsb pdb:2F16|rcsb pdb:2FAK|rcsb pdb:2GPL|rcsb pdb:2ZCY|rcsb pdb:3BDM|rcsb pdb:3D29|rcsb pdb:3DY3|rcsb pdb:3DY4|rcsb pdb:3E47|rcsb pdb:3GPJ|rcsb pdb:3GPT|rcsb pdb:3GPW|rcsb pdb:4QVM|rcsb pdb:4QVN|rcsb pdb:4QVP|rcsb pdb:4QVQ|rcsb pdb:4QVV|rcsb pdb:4QVW|rcsb pdb:4QVY|rcsb pdb:4QW0|rcsb pdb:4QW1|rcsb pdb:4QW3|rcsb pdb:4QW4|rcsb pdb:4QW5|rcsb pdb:4QW6|rcsb pdb:4QW7|rcsb pdb:4QWF|rcsb pdb:4QWG|rcsb pdb:4QWI|rcsb pdb:4QWJ|rcsb pdb:4QWK|rcsb pdb:4QWL|rcsb pdb:4QWR|rcsb pdb:4QWS|rcsb pdb:4QWU|rcsb pdb:4QWX|rcsb pdb:4QXJ|rcsb pdb:4QZ0|rcsb pdb:4QZ1|rcsb pdb:4QZ2|rcsb pdb:4QZ3|rcsb pdb:4QZ4|rcsb pdb:4QZ5|rcsb pdb:4QZ6|rcsb pdb:4QZ7|rcsb pdb:4QZW|rcsb pdb:4QZX|rcsb pdb:4QZZ|rcsb pdb:4R00|rcsb pdb:4R02|rcsb pdb:4R17|rcsb pdb:4R18|rcsb pdb:4RUR|rcsb pdb:4V7O|rcsb pdb:4X6Z|rcsb pdb:4Y69|rcsb pdb:4Y6A|rcsb pdb:4Y6V|rcsb pdb:4Y6Z|rcsb pdb:4Y70|rcsb pdb:4Y74|rcsb pdb:4Y75|rcsb pdb:4Y77|rcsb pdb:4Y78|rcsb pdb:4Y7W|rcsb pdb:5LTT|rcsb pdb:5M2B|rcsb pdb:5MP9|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5NIF|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6G7F|rcsb pdb:6G8M|rcsb pdb:6G8N|rcsb pdb:6GOP|rcsb pdb:6H39|rcsb pdb:6HTB|rcsb pdb:6HTC|rcsb pdb:6HTD|rcsb pdb:6HTP|rcsb pdb:6HTR|rcsb pdb:6HUB|rcsb pdb:6HUC|rcsb pdb:6HUQ|rcsb pdb:6HUU|rcsb pdb:6HUV|rcsb pdb:6HV3|rcsb pdb:6HV4|rcsb pdb:6HV5|rcsb pdb:6HV7|rcsb pdb:6HVA|rcsb pdb:6HVR|rcsb pdb:6HVS|rcsb pdb:6HVT|rcsb pdb:6HVU|rcsb pdb:6HVV|rcsb pdb:5L5S|rcsb pdb:5L5T|rcsb pdb:5L5U|rcsb pdb:5L5V|rcsb pdb:5L5W|rcsb pdb:5L5X|rcsb pdb:5L5Y|rcsb pdb:5L5Z|rcsb pdb:5L60|rcsb pdb:5L61|rcsb pdb:5L62|rcsb pdb:5L63|rcsb pdb:5L64|rcsb pdb:5L65|rcsb pdb:5L66|rcsb pdb:5L67|rcsb pdb:5L68|rcsb pdb:5L69|rcsb pdb:5L6A|rcsb pdb:5L6B|rcsb pdb:5L6C|rcsb pdb:5LAI|rcsb pdb:5LAJ|rcsb pdb:6HVW|rcsb pdb:6HVX|rcsb pdb:6HVY|rcsb pdb:6HW0|rcsb pdb:6HW3|rcsb pdb:6HW4|rcsb pdb:6HW5|rcsb pdb:6HW6|rcsb pdb:6HW7|rcsb pdb:6HW8|rcsb pdb:6HW9|rcsb pdb:6HWA|rcsb pdb:6HWB|rcsb pdb:6HWC|rcsb pdb:6HWD|rcsb pdb:6HWE|rcsb pdb:6HWF|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2X|rcsb pdb:6J30|rcsb pdb:6ZOU|rcsb pdb:6ZP6|rcsb pdb:6ZP8|rcsb pdb:7LS5|rcsb pdb:7LS6|rcsb pdb:7LSX|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|rcsb pdb:6J2Q|refseq:NP_014045.1|sgd:S000004931|mint:P40302|dip:DIP-1528N|sgd:YMR314W(identity)	-	isoform-comment:No experimental confirmation available.	crc64:C43CBCC1C6B9E39E	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:npId9tC7VoLN/jteoBiRbSYChPs9606	rogid:C9GPb0JAklkBz0t/YYqRMNEiQss559292	intact-crc:758146828B7674E2|rigid:VE5JD2ppecB/NGSKdKwKlvM1j3o	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8TAP6	uniprotkb:P40302	intact:EBI-742887|ensembl:ENSP00000262127|uniprotkb:Q658N5|uniprotkb:Q9H9U7|uniprotkb:B0YJB2|uniprotkb:B4DXG5|uniprotkb:B4DZW1	intact:EBI-13955|ensemblfungi:YMR314W|uniprotkb:D6W0E1	psi-mi:cep76_human(display_long)|uniprotkb:CEP76(gene name)|psi-mi:CEP76(display_short)|uniprotkb:C18orf9(gene name synonym)	psi-mi:psa6_yeast(display_long)|uniprotkb:PRE5(gene name)|psi-mi:PRE5(display_short)|uniprotkb:YMR314W(locus name)|uniprotkb:YM9924.06(orf name)|uniprotkb:Proteasome component PRE5(gene name synonym)|uniprotkb:Macropain subunit PRE5(gene name synonym)|uniprotkb:Proteinase YSCE subunit PRE5(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit PRE5(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11559735|imex:IM-24995-4868	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_079175.2|ensembl:ENSG00000101624(gene)|ensembl:ENST00000262127(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0046599"(regulation of centriole replication)|interpro:IPR028926|interpro:IPR038765|mint:Q8TAP6|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_001258918.1|entrezgene/locuslink:79959(identity)	rcsb pdb:4Y8T|rcsb pdb:4Y8U|rcsb pdb:4Y9Y|rcsb pdb:4Y9Z|rcsb pdb:4YA0|rcsb pdb:4YA1|rcsb pdb:4YA2|rcsb pdb:4YA3|rcsb pdb:4YA4|rcsb pdb:4YA5|rcsb pdb:4Y7X|rcsb pdb:4Y7Y|rcsb pdb:4Y80|rcsb pdb:4Y81|rcsb pdb:4Y82|rcsb pdb:4Y84|rcsb pdb:4Y8G|rcsb pdb:4Y8H|rcsb pdb:4Y8I|rcsb pdb:4Y8J|rcsb pdb:4Y8K|rcsb pdb:4Y8L|rcsb pdb:4Y8M|rcsb pdb:4Y8N|rcsb pdb:4Y8O|rcsb pdb:4Y8P|rcsb pdb:4Y8Q|rcsb pdb:4Y8R|rcsb pdb:4Y8S|rcsb pdb:5FG7|rcsb pdb:5FG9|rcsb pdb:5FGA|rcsb pdb:4YA7|rcsb pdb:4YA9|rcsb pdb:4Z1L|rcsb pdb:5A5B|rcsb pdb:5AHJ|rcsb pdb:5BOU|rcsb pdb:5BXL|rcsb pdb:5BXN|rcsb pdb:5CGF|rcsb pdb:5CGG|rcsb pdb:5CGH|rcsb pdb:5CGI|rcsb pdb:5CZ4|rcsb pdb:5CZ5|rcsb pdb:5CZ6|rcsb pdb:5CZ7|rcsb pdb:5CZ8|rcsb pdb:5CZ9|rcsb pdb:5CZA|rcsb pdb:5D0S|rcsb pdb:5D0T|rcsb pdb:5D0V|rcsb pdb:5D0W|rcsb pdb:5D0X|rcsb pdb:5D0Z|rcsb pdb:5DKI|rcsb pdb:5DKJ|rcsb pdb:5FGD|rcsb pdb:3HYE|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:3MG0|rcsb pdb:3MG4|rcsb pdb:3MG6|rcsb pdb:3MG7|rcsb pdb:3MG8|rcsb pdb:3NZJ|rcsb pdb:3NZW|rcsb pdb:3NZX|rcsb pdb:3OEU|rcsb pdb:3OEV|rcsb pdb:3OKJ|rcsb pdb:3SDI|rcsb pdb:3SDK|rcsb pdb:3SHJ|rcsb pdb:3TDD|rcsb pdb:3UN4|rcsb pdb:3UN8|rcsb pdb:3WXR|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:4EU2|rcsb pdb:4FZC|rcsb pdb:4FZG|rcsb pdb:4G4S|rcsb pdb:4GK7|rcsb pdb:4HNP|rcsb pdb:4HRC|rcsb pdb:4HRD|rcsb pdb:4INR|rcsb pdb:4INT|rcsb pdb:4INU|rcsb pdb:4J70|rcsb pdb:4JSQ|rcsb pdb:4JSU|rcsb pdb:4JT0|rcsb pdb:4LQI|rcsb pdb:4LTC|rcsb pdb:4NNN|rcsb pdb:4NNW|rcsb pdb:4NO1|rcsb pdb:4NO6|rcsb pdb:4NO8|rcsb pdb:4NO9|rcsb pdb:5FGE|rcsb pdb:5FGF|rcsb pdb:5FGG|rcsb pdb:5FGH|rcsb pdb:5FGI|rcsb pdb:5FHS|rcsb pdb:5JHR|rcsb pdb:5JHS|rcsb pdb:5L52|rcsb pdb:5L54|rcsb pdb:5L55|rcsb pdb:5L5A|rcsb pdb:5L5B|rcsb pdb:5L5D|rcsb pdb:5L5E|rcsb pdb:5L5F|rcsb pdb:5L5H|rcsb pdb:5L5I|rcsb pdb:5L5J|rcsb pdb:5L5O|rcsb pdb:5L5P|rcsb pdb:5L5Q|rcsb pdb:5L5R|rcsb pdb:4Q1S|rcsb pdb:4QBY|rcsb pdb:4QLQ|rcsb pdb:4QLS|rcsb pdb:4QLT|rcsb pdb:4QLU|rcsb pdb:4QLV|rcsb pdb:4QUX|rcsb pdb:4QUY|rcsb pdb:4QV0|rcsb pdb:4QV1|rcsb pdb:4QV3|rcsb pdb:4QV4|rcsb pdb:4QV5|rcsb pdb:4QV6|rcsb pdb:4QV7|rcsb pdb:4QV8|rcsb pdb:4QV9|rcsb pdb:4QVL|ensemblfungi:YMR314W(gene)|ensemblfungi:YMR314W_mRNA(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0042175"(nuclear outer membrane-endoplasmic reticulum membrane network)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR035144|rcsb pdb:1FNT|rcsb pdb:1G0U|rcsb pdb:1G65|rcsb pdb:1JD2|rcsb pdb:1RYP|rcsb pdb:1Z7Q|rcsb pdb:2F16|rcsb pdb:2FAK|rcsb pdb:2GPL|rcsb pdb:2ZCY|rcsb pdb:3BDM|rcsb pdb:3D29|rcsb pdb:3DY3|rcsb pdb:3DY4|rcsb pdb:3E47|rcsb pdb:3GPJ|rcsb pdb:3GPT|rcsb pdb:3GPW|rcsb pdb:4QVM|rcsb pdb:4QVN|rcsb pdb:4QVP|rcsb pdb:4QVQ|rcsb pdb:4QVV|rcsb pdb:4QVW|rcsb pdb:4QVY|rcsb pdb:4QW0|rcsb pdb:4QW1|rcsb pdb:4QW3|rcsb pdb:4QW4|rcsb pdb:4QW5|rcsb pdb:4QW6|rcsb pdb:4QW7|rcsb pdb:4QWF|rcsb pdb:4QWG|rcsb pdb:4QWI|rcsb pdb:4QWJ|rcsb pdb:4QWK|rcsb pdb:4QWL|rcsb pdb:4QWR|rcsb pdb:4QWS|rcsb pdb:4QWU|rcsb pdb:4QWX|rcsb pdb:4QXJ|rcsb pdb:4QZ0|rcsb pdb:4QZ1|rcsb pdb:4QZ2|rcsb pdb:4QZ3|rcsb pdb:4QZ4|rcsb pdb:4QZ5|rcsb pdb:4QZ6|rcsb pdb:4QZ7|rcsb pdb:4QZW|rcsb pdb:4QZX|rcsb pdb:4QZZ|rcsb pdb:4R00|rcsb pdb:4R02|rcsb pdb:4R17|rcsb pdb:4R18|rcsb pdb:4RUR|rcsb pdb:4V7O|rcsb pdb:4X6Z|rcsb pdb:4Y69|rcsb pdb:4Y6A|rcsb pdb:4Y6V|rcsb pdb:4Y6Z|rcsb pdb:4Y70|rcsb pdb:4Y74|rcsb pdb:4Y75|rcsb pdb:4Y77|rcsb pdb:4Y78|rcsb pdb:4Y7W|rcsb pdb:5LTT|rcsb pdb:5M2B|rcsb pdb:5MP9|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5NIF|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6G7F|rcsb pdb:6G8M|rcsb pdb:6G8N|rcsb pdb:6GOP|rcsb pdb:6H39|rcsb pdb:6HTB|rcsb pdb:6HTC|rcsb pdb:6HTD|rcsb pdb:6HTP|rcsb pdb:6HTR|rcsb pdb:6HUB|rcsb pdb:6HUC|rcsb pdb:6HUQ|rcsb pdb:6HUU|rcsb pdb:6HUV|rcsb pdb:6HV3|rcsb pdb:6HV4|rcsb pdb:6HV5|rcsb pdb:6HV7|rcsb pdb:6HVA|rcsb pdb:6HVR|rcsb pdb:6HVS|rcsb pdb:6HVT|rcsb pdb:6HVU|rcsb pdb:6HVV|rcsb pdb:5L5S|rcsb pdb:5L5T|rcsb pdb:5L5U|rcsb pdb:5L5V|rcsb pdb:5L5W|rcsb pdb:5L5X|rcsb pdb:5L5Y|rcsb pdb:5L5Z|rcsb pdb:5L60|rcsb pdb:5L61|rcsb pdb:5L62|rcsb pdb:5L63|rcsb pdb:5L64|rcsb pdb:5L65|rcsb pdb:5L66|rcsb pdb:5L67|rcsb pdb:5L68|rcsb pdb:5L69|rcsb pdb:5L6A|rcsb pdb:5L6B|rcsb pdb:5L6C|rcsb pdb:5LAI|rcsb pdb:5LAJ|rcsb pdb:6HVW|rcsb pdb:6HVX|rcsb pdb:6HVY|rcsb pdb:6HW0|rcsb pdb:6HW3|rcsb pdb:6HW4|rcsb pdb:6HW5|rcsb pdb:6HW6|rcsb pdb:6HW7|rcsb pdb:6HW8|rcsb pdb:6HW9|rcsb pdb:6HWA|rcsb pdb:6HWB|rcsb pdb:6HWC|rcsb pdb:6HWD|rcsb pdb:6HWE|rcsb pdb:6HWF|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2X|rcsb pdb:6J30|rcsb pdb:6ZOU|rcsb pdb:6ZP6|rcsb pdb:6ZP8|rcsb pdb:7LS5|rcsb pdb:7LS6|rcsb pdb:7LSX|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|rcsb pdb:6J2Q|refseq:NP_014045.1|sgd:S000004931|mint:P40302|dip:DIP-1528N|sgd:YMR314W(identity)	-	-	crc64:C43CBCC1C6B9E39E	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:fWzb8oIU35oVWomyDrf8u5sbxUk9606	rogid:C9GPb0JAklkBz0t/YYqRMNEiQss559292	intact-crc:239C9E9FD0F403C7|rigid:DHzAsX9ZS6IcNW2eAj2hsBeJhXE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40302	uniprotkb:Q96CV9	intact:EBI-13955|ensemblfungi:YMR314W|uniprotkb:D6W0E1	intact:EBI-748974|uniprotkb:Q5T672|uniprotkb:Q5T673|uniprotkb:Q5T674|uniprotkb:Q5T675|uniprotkb:Q7LDL9|uniprotkb:Q8N562|uniprotkb:Q9UET9|uniprotkb:Q9UEV4|uniprotkb:Q9Y218|uniprotkb:B3KP00|uniprotkb:D3DRS4|uniprotkb:D3DRS8|ensembl:ENSP00000263036|ensembl:ENSP00000368021|ensembl:ENSP00000368022|ensembl:ENSP00000368032	psi-mi:psa6_yeast(display_long)|uniprotkb:PRE5(gene name)|psi-mi:PRE5(display_short)|uniprotkb:YMR314W(locus name)|uniprotkb:YM9924.06(orf name)|uniprotkb:Proteasome component PRE5(gene name synonym)|uniprotkb:Macropain subunit PRE5(gene name synonym)|uniprotkb:Proteinase YSCE subunit PRE5(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit PRE5(gene name synonym)	psi-mi:optn_human(display_long)|uniprotkb:HYPL(gene name synonym)|uniprotkb:Optic neuropathy-inducing protein(gene name synonym)|uniprotkb:E3-14.7K-interacting protein(gene name synonym)|uniprotkb:FIP-2(gene name synonym)|uniprotkb:Huntingtin-interacting protein L(gene name synonym)|uniprotkb:Huntingtin yeast partner L(gene name synonym)|uniprotkb:NEMO-related protein(gene name synonym)|uniprotkb:Transcription factor IIIA-interacting protein(gene name synonym)|uniprotkb:OPTN(gene name)|psi-mi:OPTN(display_short)|uniprotkb:FIP2(gene name synonym)|uniprotkb:GLC1E(gene name synonym)|uniprotkb:NRP(gene name synonym)|uniprotkb:HIP7(gene name synonym)|uniprotkb:Huntingtin-interacting protein 7(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11559744|imex:IM-24995-4869	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:4Y8T|rcsb pdb:4Y8U|rcsb pdb:4Y9Y|rcsb pdb:4Y9Z|rcsb pdb:4YA0|rcsb pdb:4YA1|rcsb pdb:4YA2|rcsb pdb:4YA3|rcsb pdb:4YA4|rcsb pdb:4YA5|rcsb pdb:4Y7X|rcsb pdb:4Y7Y|rcsb pdb:4Y80|rcsb pdb:4Y81|rcsb pdb:4Y82|rcsb pdb:4Y84|rcsb pdb:4Y8G|rcsb pdb:4Y8H|rcsb pdb:4Y8I|rcsb pdb:4Y8J|rcsb pdb:4Y8K|rcsb pdb:4Y8L|rcsb pdb:4Y8M|rcsb pdb:4Y8N|rcsb pdb:4Y8O|rcsb pdb:4Y8P|rcsb pdb:4Y8Q|rcsb pdb:4Y8R|rcsb pdb:4Y8S|rcsb pdb:5FG7|rcsb pdb:5FG9|rcsb pdb:5FGA|rcsb pdb:4YA7|rcsb pdb:4YA9|rcsb pdb:4Z1L|rcsb pdb:5A5B|rcsb pdb:5AHJ|rcsb pdb:5BOU|rcsb pdb:5BXL|rcsb pdb:5BXN|rcsb pdb:5CGF|rcsb pdb:5CGG|rcsb pdb:5CGH|rcsb pdb:5CGI|rcsb pdb:5CZ4|rcsb pdb:5CZ5|rcsb pdb:5CZ6|rcsb pdb:5CZ7|rcsb pdb:5CZ8|rcsb pdb:5CZ9|rcsb pdb:5CZA|rcsb pdb:5D0S|rcsb pdb:5D0T|rcsb pdb:5D0V|rcsb pdb:5D0W|rcsb pdb:5D0X|rcsb pdb:5D0Z|rcsb pdb:5DKI|rcsb pdb:5DKJ|rcsb pdb:5FGD|rcsb pdb:3HYE|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:3MG0|rcsb pdb:3MG4|rcsb pdb:3MG6|rcsb pdb:3MG7|rcsb pdb:3MG8|rcsb pdb:3NZJ|rcsb pdb:3NZW|rcsb pdb:3NZX|rcsb pdb:3OEU|rcsb pdb:3OEV|rcsb pdb:3OKJ|rcsb pdb:3SDI|rcsb pdb:3SDK|rcsb pdb:3SHJ|rcsb pdb:3TDD|rcsb pdb:3UN4|rcsb pdb:3UN8|rcsb pdb:3WXR|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:4EU2|rcsb pdb:4FZC|rcsb pdb:4FZG|rcsb pdb:4G4S|rcsb pdb:4GK7|rcsb pdb:4HNP|rcsb pdb:4HRC|rcsb pdb:4HRD|rcsb pdb:4INR|rcsb pdb:4INT|rcsb pdb:4INU|rcsb pdb:4J70|rcsb pdb:4JSQ|rcsb pdb:4JSU|rcsb pdb:4JT0|rcsb pdb:4LQI|rcsb pdb:4LTC|rcsb pdb:4NNN|rcsb pdb:4NNW|rcsb pdb:4NO1|rcsb pdb:4NO6|rcsb pdb:4NO8|rcsb pdb:4NO9|rcsb pdb:5FGE|rcsb pdb:5FGF|rcsb pdb:5FGG|rcsb pdb:5FGH|rcsb pdb:5FGI|rcsb pdb:5FHS|rcsb pdb:5JHR|rcsb pdb:5JHS|rcsb pdb:5L52|rcsb pdb:5L54|rcsb pdb:5L55|rcsb pdb:5L5A|rcsb pdb:5L5B|rcsb pdb:5L5D|rcsb pdb:5L5E|rcsb pdb:5L5F|rcsb pdb:5L5H|rcsb pdb:5L5I|rcsb pdb:5L5J|rcsb pdb:5L5O|rcsb pdb:5L5P|rcsb pdb:5L5Q|rcsb pdb:5L5R|rcsb pdb:4Q1S|rcsb pdb:4QBY|rcsb pdb:4QLQ|rcsb pdb:4QLS|rcsb pdb:4QLT|rcsb pdb:4QLU|rcsb pdb:4QLV|rcsb pdb:4QUX|rcsb pdb:4QUY|rcsb pdb:4QV0|rcsb pdb:4QV1|rcsb pdb:4QV3|rcsb pdb:4QV4|rcsb pdb:4QV5|rcsb pdb:4QV6|rcsb pdb:4QV7|rcsb pdb:4QV8|rcsb pdb:4QV9|rcsb pdb:4QVL|ensemblfungi:YMR314W(gene)|ensemblfungi:YMR314W_mRNA(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0042175"(nuclear outer membrane-endoplasmic reticulum membrane network)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR035144|rcsb pdb:1FNT|rcsb pdb:1G0U|rcsb pdb:1G65|rcsb pdb:1JD2|rcsb pdb:1RYP|rcsb pdb:1Z7Q|rcsb pdb:2F16|rcsb pdb:2FAK|rcsb pdb:2GPL|rcsb pdb:2ZCY|rcsb pdb:3BDM|rcsb pdb:3D29|rcsb pdb:3DY3|rcsb pdb:3DY4|rcsb pdb:3E47|rcsb pdb:3GPJ|rcsb pdb:3GPT|rcsb pdb:3GPW|rcsb pdb:4QVM|rcsb pdb:4QVN|rcsb pdb:4QVP|rcsb pdb:4QVQ|rcsb pdb:4QVV|rcsb pdb:4QVW|rcsb pdb:4QVY|rcsb pdb:4QW0|rcsb pdb:4QW1|rcsb pdb:4QW3|rcsb pdb:4QW4|rcsb pdb:4QW5|rcsb pdb:4QW6|rcsb pdb:4QW7|rcsb pdb:4QWF|rcsb pdb:4QWG|rcsb pdb:4QWI|rcsb pdb:4QWJ|rcsb pdb:4QWK|rcsb pdb:4QWL|rcsb pdb:4QWR|rcsb pdb:4QWS|rcsb pdb:4QWU|rcsb pdb:4QWX|rcsb pdb:4QXJ|rcsb pdb:4QZ0|rcsb pdb:4QZ1|rcsb pdb:4QZ2|rcsb pdb:4QZ3|rcsb pdb:4QZ4|rcsb pdb:4QZ5|rcsb pdb:4QZ6|rcsb pdb:4QZ7|rcsb pdb:4QZW|rcsb pdb:4QZX|rcsb pdb:4QZZ|rcsb pdb:4R00|rcsb pdb:4R02|rcsb pdb:4R17|rcsb pdb:4R18|rcsb pdb:4RUR|rcsb pdb:4V7O|rcsb pdb:4X6Z|rcsb pdb:4Y69|rcsb pdb:4Y6A|rcsb pdb:4Y6V|rcsb pdb:4Y6Z|rcsb pdb:4Y70|rcsb pdb:4Y74|rcsb pdb:4Y75|rcsb pdb:4Y77|rcsb pdb:4Y78|rcsb pdb:4Y7W|rcsb pdb:5LTT|rcsb pdb:5M2B|rcsb pdb:5MP9|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5NIF|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6G7F|rcsb pdb:6G8M|rcsb pdb:6G8N|rcsb pdb:6GOP|rcsb pdb:6H39|rcsb pdb:6HTB|rcsb pdb:6HTC|rcsb pdb:6HTD|rcsb pdb:6HTP|rcsb pdb:6HTR|rcsb pdb:6HUB|rcsb pdb:6HUC|rcsb pdb:6HUQ|rcsb pdb:6HUU|rcsb pdb:6HUV|rcsb pdb:6HV3|rcsb pdb:6HV4|rcsb pdb:6HV5|rcsb pdb:6HV7|rcsb pdb:6HVA|rcsb pdb:6HVR|rcsb pdb:6HVS|rcsb pdb:6HVT|rcsb pdb:6HVU|rcsb pdb:6HVV|rcsb pdb:5L5S|rcsb pdb:5L5T|rcsb pdb:5L5U|rcsb pdb:5L5V|rcsb pdb:5L5W|rcsb pdb:5L5X|rcsb pdb:5L5Y|rcsb pdb:5L5Z|rcsb pdb:5L60|rcsb pdb:5L61|rcsb pdb:5L62|rcsb pdb:5L63|rcsb pdb:5L64|rcsb pdb:5L65|rcsb pdb:5L66|rcsb pdb:5L67|rcsb pdb:5L68|rcsb pdb:5L69|rcsb pdb:5L6A|rcsb pdb:5L6B|rcsb pdb:5L6C|rcsb pdb:5LAI|rcsb pdb:5LAJ|rcsb pdb:6HVW|rcsb pdb:6HVX|rcsb pdb:6HVY|rcsb pdb:6HW0|rcsb pdb:6HW3|rcsb pdb:6HW4|rcsb pdb:6HW5|rcsb pdb:6HW6|rcsb pdb:6HW7|rcsb pdb:6HW8|rcsb pdb:6HW9|rcsb pdb:6HWA|rcsb pdb:6HWB|rcsb pdb:6HWC|rcsb pdb:6HWD|rcsb pdb:6HWE|rcsb pdb:6HWF|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2X|rcsb pdb:6J30|rcsb pdb:6ZOU|rcsb pdb:6ZP6|rcsb pdb:6ZP8|rcsb pdb:7LS5|rcsb pdb:7LS6|rcsb pdb:7LSX|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|rcsb pdb:6J2Q|refseq:NP_014045.1|sgd:S000004931|mint:P40302|dip:DIP-1528N|sgd:YMR314W(identity)	refseq:NP_001008212.1|refseq:NP_001008213.1|refseq:NP_001008214.1|refseq:NP_068815.2|ensembl:ENSG00000123240(gene)|ensembl:ENST00000263036(transcript)|ensembl:ENST00000378747(transcript)|ensembl:ENST00000378748(transcript)|ensembl:ENST00000378757(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001920"(negative regulation of receptor recycling)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0007030"(Golgi organization)|go:"GO:0007165"(signal transduction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008219"(cell death)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0061734"(parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:1904417"(positive regulation of xenophagy)|interpro:IPR021063|interpro:IPR032419|interpro:IPR032939|interpro:IPR034735|mint:Q96CV9|rcsb pdb:2LO4|rcsb pdb:2LUE|rcsb pdb:3VTV|rcsb pdb:3VTW|rcsb pdb:5AAZ|rcsb pdb:5B83|rcsb pdb:5EOA|rcsb pdb:5EOF|rcsb pdb:7CZM|reactome:R-HSA-2565942|reactome:R-HSA-8854214|dip:DIP-42001N|entrezgene/locuslink:10133(identity)	-	crc64:C43CBCC1C6B9E39E	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2018/04/06	rogid:C9GPb0JAklkBz0t/YYqRMNEiQss559292	rogid:jcCTXDx1bJq3K5mgNUD73jeWeBU9606	intact-crc:90194502AF70AEB3|rigid:cavY4vnk2ijUHCXNWZ63l8OL7sk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9H257-2	uniprotkb:P40302	intact:EBI-11530605|ensembl:ENSP00000360799	intact:EBI-13955|ensemblfungi:YMR314W|uniprotkb:D6W0E1	psi-mi:q9h257-2(display_long)|uniprotkb:CARD9(gene name)|psi-mi:CARD9(display_short)	psi-mi:psa6_yeast(display_long)|uniprotkb:PRE5(gene name)|psi-mi:PRE5(display_short)|uniprotkb:YMR314W(locus name)|uniprotkb:YM9924.06(orf name)|uniprotkb:Proteasome component PRE5(gene name synonym)|uniprotkb:Macropain subunit PRE5(gene name synonym)|uniprotkb:Proteinase YSCE subunit PRE5(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit PRE5(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11559762|imex:IM-24995-4871	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-751319(isoform-parent)|uniprotkb:Q9H257-2(isoform-parent)|ensembl:ENSG00000187796(gene)|ensembl:ENST00000371734(transcript)|entrezgene/locuslink:64170(identity)	rcsb pdb:4Y8T|rcsb pdb:4Y8U|rcsb pdb:4Y9Y|rcsb pdb:4Y9Z|rcsb pdb:4YA0|rcsb pdb:4YA1|rcsb pdb:4YA2|rcsb pdb:4YA3|rcsb pdb:4YA4|rcsb pdb:4YA5|rcsb pdb:4Y7X|rcsb pdb:4Y7Y|rcsb pdb:4Y80|rcsb pdb:4Y81|rcsb pdb:4Y82|rcsb pdb:4Y84|rcsb pdb:4Y8G|rcsb pdb:4Y8H|rcsb pdb:4Y8I|rcsb pdb:4Y8J|rcsb pdb:4Y8K|rcsb pdb:4Y8L|rcsb pdb:4Y8M|rcsb pdb:4Y8N|rcsb pdb:4Y8O|rcsb pdb:4Y8P|rcsb pdb:4Y8Q|rcsb pdb:4Y8R|rcsb pdb:4Y8S|rcsb pdb:5FG7|rcsb pdb:5FG9|rcsb pdb:5FGA|rcsb pdb:4YA7|rcsb pdb:4YA9|rcsb pdb:4Z1L|rcsb pdb:5A5B|rcsb pdb:5AHJ|rcsb pdb:5BOU|rcsb pdb:5BXL|rcsb pdb:5BXN|rcsb pdb:5CGF|rcsb pdb:5CGG|rcsb pdb:5CGH|rcsb pdb:5CGI|rcsb pdb:5CZ4|rcsb pdb:5CZ5|rcsb pdb:5CZ6|rcsb pdb:5CZ7|rcsb pdb:5CZ8|rcsb pdb:5CZ9|rcsb pdb:5CZA|rcsb pdb:5D0S|rcsb pdb:5D0T|rcsb pdb:5D0V|rcsb pdb:5D0W|rcsb pdb:5D0X|rcsb pdb:5D0Z|rcsb pdb:5DKI|rcsb pdb:5DKJ|rcsb pdb:5FGD|rcsb pdb:3HYE|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:3MG0|rcsb pdb:3MG4|rcsb pdb:3MG6|rcsb pdb:3MG7|rcsb pdb:3MG8|rcsb pdb:3NZJ|rcsb pdb:3NZW|rcsb pdb:3NZX|rcsb pdb:3OEU|rcsb pdb:3OEV|rcsb pdb:3OKJ|rcsb pdb:3SDI|rcsb pdb:3SDK|rcsb pdb:3SHJ|rcsb pdb:3TDD|rcsb pdb:3UN4|rcsb pdb:3UN8|rcsb pdb:3WXR|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:4EU2|rcsb pdb:4FZC|rcsb pdb:4FZG|rcsb pdb:4G4S|rcsb pdb:4GK7|rcsb pdb:4HNP|rcsb pdb:4HRC|rcsb pdb:4HRD|rcsb pdb:4INR|rcsb pdb:4INT|rcsb pdb:4INU|rcsb pdb:4J70|rcsb pdb:4JSQ|rcsb pdb:4JSU|rcsb pdb:4JT0|rcsb pdb:4LQI|rcsb pdb:4LTC|rcsb pdb:4NNN|rcsb pdb:4NNW|rcsb pdb:4NO1|rcsb pdb:4NO6|rcsb pdb:4NO8|rcsb pdb:4NO9|rcsb pdb:5FGE|rcsb pdb:5FGF|rcsb pdb:5FGG|rcsb pdb:5FGH|rcsb pdb:5FGI|rcsb pdb:5FHS|rcsb pdb:5JHR|rcsb pdb:5JHS|rcsb pdb:5L52|rcsb pdb:5L54|rcsb pdb:5L55|rcsb pdb:5L5A|rcsb pdb:5L5B|rcsb pdb:5L5D|rcsb pdb:5L5E|rcsb pdb:5L5F|rcsb pdb:5L5H|rcsb pdb:5L5I|rcsb pdb:5L5J|rcsb pdb:5L5O|rcsb pdb:5L5P|rcsb pdb:5L5Q|rcsb pdb:5L5R|rcsb pdb:4Q1S|rcsb pdb:4QBY|rcsb pdb:4QLQ|rcsb pdb:4QLS|rcsb pdb:4QLT|rcsb pdb:4QLU|rcsb pdb:4QLV|rcsb pdb:4QUX|rcsb pdb:4QUY|rcsb pdb:4QV0|rcsb pdb:4QV1|rcsb pdb:4QV3|rcsb pdb:4QV4|rcsb pdb:4QV5|rcsb pdb:4QV6|rcsb pdb:4QV7|rcsb pdb:4QV8|rcsb pdb:4QV9|rcsb pdb:4QVL|ensemblfungi:YMR314W(gene)|ensemblfungi:YMR314W_mRNA(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0042175"(nuclear outer membrane-endoplasmic reticulum membrane network)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR035144|rcsb pdb:1FNT|rcsb pdb:1G0U|rcsb pdb:1G65|rcsb pdb:1JD2|rcsb pdb:1RYP|rcsb pdb:1Z7Q|rcsb pdb:2F16|rcsb pdb:2FAK|rcsb pdb:2GPL|rcsb pdb:2ZCY|rcsb pdb:3BDM|rcsb pdb:3D29|rcsb pdb:3DY3|rcsb pdb:3DY4|rcsb pdb:3E47|rcsb pdb:3GPJ|rcsb pdb:3GPT|rcsb pdb:3GPW|rcsb pdb:4QVM|rcsb pdb:4QVN|rcsb pdb:4QVP|rcsb pdb:4QVQ|rcsb pdb:4QVV|rcsb pdb:4QVW|rcsb pdb:4QVY|rcsb pdb:4QW0|rcsb pdb:4QW1|rcsb pdb:4QW3|rcsb pdb:4QW4|rcsb pdb:4QW5|rcsb pdb:4QW6|rcsb pdb:4QW7|rcsb pdb:4QWF|rcsb pdb:4QWG|rcsb pdb:4QWI|rcsb pdb:4QWJ|rcsb pdb:4QWK|rcsb pdb:4QWL|rcsb pdb:4QWR|rcsb pdb:4QWS|rcsb pdb:4QWU|rcsb pdb:4QWX|rcsb pdb:4QXJ|rcsb pdb:4QZ0|rcsb pdb:4QZ1|rcsb pdb:4QZ2|rcsb pdb:4QZ3|rcsb pdb:4QZ4|rcsb pdb:4QZ5|rcsb pdb:4QZ6|rcsb pdb:4QZ7|rcsb pdb:4QZW|rcsb pdb:4QZX|rcsb pdb:4QZZ|rcsb pdb:4R00|rcsb pdb:4R02|rcsb pdb:4R17|rcsb pdb:4R18|rcsb pdb:4RUR|rcsb pdb:4V7O|rcsb pdb:4X6Z|rcsb pdb:4Y69|rcsb pdb:4Y6A|rcsb pdb:4Y6V|rcsb pdb:4Y6Z|rcsb pdb:4Y70|rcsb pdb:4Y74|rcsb pdb:4Y75|rcsb pdb:4Y77|rcsb pdb:4Y78|rcsb pdb:4Y7W|rcsb pdb:5LTT|rcsb pdb:5M2B|rcsb pdb:5MP9|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5NIF|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6G7F|rcsb pdb:6G8M|rcsb pdb:6G8N|rcsb pdb:6GOP|rcsb pdb:6H39|rcsb pdb:6HTB|rcsb pdb:6HTC|rcsb pdb:6HTD|rcsb pdb:6HTP|rcsb pdb:6HTR|rcsb pdb:6HUB|rcsb pdb:6HUC|rcsb pdb:6HUQ|rcsb pdb:6HUU|rcsb pdb:6HUV|rcsb pdb:6HV3|rcsb pdb:6HV4|rcsb pdb:6HV5|rcsb pdb:6HV7|rcsb pdb:6HVA|rcsb pdb:6HVR|rcsb pdb:6HVS|rcsb pdb:6HVT|rcsb pdb:6HVU|rcsb pdb:6HVV|rcsb pdb:5L5S|rcsb pdb:5L5T|rcsb pdb:5L5U|rcsb pdb:5L5V|rcsb pdb:5L5W|rcsb pdb:5L5X|rcsb pdb:5L5Y|rcsb pdb:5L5Z|rcsb pdb:5L60|rcsb pdb:5L61|rcsb pdb:5L62|rcsb pdb:5L63|rcsb pdb:5L64|rcsb pdb:5L65|rcsb pdb:5L66|rcsb pdb:5L67|rcsb pdb:5L68|rcsb pdb:5L69|rcsb pdb:5L6A|rcsb pdb:5L6B|rcsb pdb:5L6C|rcsb pdb:5LAI|rcsb pdb:5LAJ|rcsb pdb:6HVW|rcsb pdb:6HVX|rcsb pdb:6HVY|rcsb pdb:6HW0|rcsb pdb:6HW3|rcsb pdb:6HW4|rcsb pdb:6HW5|rcsb pdb:6HW6|rcsb pdb:6HW7|rcsb pdb:6HW8|rcsb pdb:6HW9|rcsb pdb:6HWA|rcsb pdb:6HWB|rcsb pdb:6HWC|rcsb pdb:6HWD|rcsb pdb:6HWE|rcsb pdb:6HWF|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2X|rcsb pdb:6J30|rcsb pdb:6ZOU|rcsb pdb:6ZP6|rcsb pdb:6ZP8|rcsb pdb:7LS5|rcsb pdb:7LS6|rcsb pdb:7LSX|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|rcsb pdb:6J2Q|refseq:NP_014045.1|sgd:S000004931|mint:P40302|dip:DIP-1528N|sgd:YMR314W(identity)	-	isoform-comment:No experimental confirmation available.	crc64:C43CBCC1C6B9E39E	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:ZXH7B3K5NAzF1LZaeK50ciH1RTE9606	rogid:C9GPb0JAklkBz0t/YYqRMNEiQss559292	intact-crc:AF9C54D798AC891E|rigid:VeHZM7S8tZjQXJfmOgOF/t5Ecz4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96CV9-2	uniprotkb:P40302	intact:EBI-9091423|ensembl:ENSP00000368027|ensembl:ENSP00000368040	intact:EBI-13955|ensemblfungi:YMR314W|uniprotkb:D6W0E1	psi-mi:q96cv9-2(display_long)|uniprotkb:E3-14.7K-interacting protein(gene name synonym)|uniprotkb:FIP-2(gene name synonym)|uniprotkb:FIP2(gene name synonym)|uniprotkb:GLC1E(gene name synonym)|uniprotkb:HIP7(gene name synonym)|uniprotkb:HYPL(gene name synonym)|uniprotkb:Huntingtin yeast partner L(gene name synonym)|uniprotkb:Huntingtin-interacting protein 7(gene name synonym)|uniprotkb:Huntingtin-interacting protein L(gene name synonym)|uniprotkb:NEMO-related protein(gene name synonym)|uniprotkb:NRP(gene name synonym)|uniprotkb:Optic neuropathy-inducing protein(gene name synonym)|uniprotkb:Transcription factor IIIA-interacting protein(gene name synonym)|uniprotkb:OPTN(gene name)|psi-mi:OPTN(display_short)	psi-mi:psa6_yeast(display_long)|uniprotkb:PRE5(gene name)|psi-mi:PRE5(display_short)|uniprotkb:YMR314W(locus name)|uniprotkb:YM9924.06(orf name)|uniprotkb:Proteasome component PRE5(gene name synonym)|uniprotkb:Macropain subunit PRE5(gene name synonym)|uniprotkb:Proteinase YSCE subunit PRE5(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit PRE5(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11559753|imex:IM-24995-4870	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-748974(isoform-parent)|ensembl:ENST00000378752(transcript)|ensembl:ENST00000378764(transcript)|ensembl:ENSG00000123240(gene)|uniprotkb:Q96CV9-2(isoform-parent)|entrezgene/locuslink:10133(identity)	rcsb pdb:4Y8T|rcsb pdb:4Y8U|rcsb pdb:4Y9Y|rcsb pdb:4Y9Z|rcsb pdb:4YA0|rcsb pdb:4YA1|rcsb pdb:4YA2|rcsb pdb:4YA3|rcsb pdb:4YA4|rcsb pdb:4YA5|rcsb pdb:4Y7X|rcsb pdb:4Y7Y|rcsb pdb:4Y80|rcsb pdb:4Y81|rcsb pdb:4Y82|rcsb pdb:4Y84|rcsb pdb:4Y8G|rcsb pdb:4Y8H|rcsb pdb:4Y8I|rcsb pdb:4Y8J|rcsb pdb:4Y8K|rcsb pdb:4Y8L|rcsb pdb:4Y8M|rcsb pdb:4Y8N|rcsb pdb:4Y8O|rcsb pdb:4Y8P|rcsb pdb:4Y8Q|rcsb pdb:4Y8R|rcsb pdb:4Y8S|rcsb pdb:5FG7|rcsb pdb:5FG9|rcsb pdb:5FGA|rcsb pdb:4YA7|rcsb pdb:4YA9|rcsb pdb:4Z1L|rcsb pdb:5A5B|rcsb pdb:5AHJ|rcsb pdb:5BOU|rcsb pdb:5BXL|rcsb pdb:5BXN|rcsb pdb:5CGF|rcsb pdb:5CGG|rcsb pdb:5CGH|rcsb pdb:5CGI|rcsb pdb:5CZ4|rcsb pdb:5CZ5|rcsb pdb:5CZ6|rcsb pdb:5CZ7|rcsb pdb:5CZ8|rcsb pdb:5CZ9|rcsb pdb:5CZA|rcsb pdb:5D0S|rcsb pdb:5D0T|rcsb pdb:5D0V|rcsb pdb:5D0W|rcsb pdb:5D0X|rcsb pdb:5D0Z|rcsb pdb:5DKI|rcsb pdb:5DKJ|rcsb pdb:5FGD|rcsb pdb:3HYE|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:3MG0|rcsb pdb:3MG4|rcsb pdb:3MG6|rcsb pdb:3MG7|rcsb pdb:3MG8|rcsb pdb:3NZJ|rcsb pdb:3NZW|rcsb pdb:3NZX|rcsb pdb:3OEU|rcsb pdb:3OEV|rcsb pdb:3OKJ|rcsb pdb:3SDI|rcsb pdb:3SDK|rcsb pdb:3SHJ|rcsb pdb:3TDD|rcsb pdb:3UN4|rcsb pdb:3UN8|rcsb pdb:3WXR|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:4EU2|rcsb pdb:4FZC|rcsb pdb:4FZG|rcsb pdb:4G4S|rcsb pdb:4GK7|rcsb pdb:4HNP|rcsb pdb:4HRC|rcsb pdb:4HRD|rcsb pdb:4INR|rcsb pdb:4INT|rcsb pdb:4INU|rcsb pdb:4J70|rcsb pdb:4JSQ|rcsb pdb:4JSU|rcsb pdb:4JT0|rcsb pdb:4LQI|rcsb pdb:4LTC|rcsb pdb:4NNN|rcsb pdb:4NNW|rcsb pdb:4NO1|rcsb pdb:4NO6|rcsb pdb:4NO8|rcsb pdb:4NO9|rcsb pdb:5FGE|rcsb pdb:5FGF|rcsb pdb:5FGG|rcsb pdb:5FGH|rcsb pdb:5FGI|rcsb pdb:5FHS|rcsb pdb:5JHR|rcsb pdb:5JHS|rcsb pdb:5L52|rcsb pdb:5L54|rcsb pdb:5L55|rcsb pdb:5L5A|rcsb pdb:5L5B|rcsb pdb:5L5D|rcsb pdb:5L5E|rcsb pdb:5L5F|rcsb pdb:5L5H|rcsb pdb:5L5I|rcsb pdb:5L5J|rcsb pdb:5L5O|rcsb pdb:5L5P|rcsb pdb:5L5Q|rcsb pdb:5L5R|rcsb pdb:4Q1S|rcsb pdb:4QBY|rcsb pdb:4QLQ|rcsb pdb:4QLS|rcsb pdb:4QLT|rcsb pdb:4QLU|rcsb pdb:4QLV|rcsb pdb:4QUX|rcsb pdb:4QUY|rcsb pdb:4QV0|rcsb pdb:4QV1|rcsb pdb:4QV3|rcsb pdb:4QV4|rcsb pdb:4QV5|rcsb pdb:4QV6|rcsb pdb:4QV7|rcsb pdb:4QV8|rcsb pdb:4QV9|rcsb pdb:4QVL|ensemblfungi:YMR314W(gene)|ensemblfungi:YMR314W_mRNA(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0042175"(nuclear outer membrane-endoplasmic reticulum membrane network)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR035144|rcsb pdb:1FNT|rcsb pdb:1G0U|rcsb pdb:1G65|rcsb pdb:1JD2|rcsb pdb:1RYP|rcsb pdb:1Z7Q|rcsb pdb:2F16|rcsb pdb:2FAK|rcsb pdb:2GPL|rcsb pdb:2ZCY|rcsb pdb:3BDM|rcsb pdb:3D29|rcsb pdb:3DY3|rcsb pdb:3DY4|rcsb pdb:3E47|rcsb pdb:3GPJ|rcsb pdb:3GPT|rcsb pdb:3GPW|rcsb pdb:4QVM|rcsb pdb:4QVN|rcsb pdb:4QVP|rcsb pdb:4QVQ|rcsb pdb:4QVV|rcsb pdb:4QVW|rcsb pdb:4QVY|rcsb pdb:4QW0|rcsb pdb:4QW1|rcsb pdb:4QW3|rcsb pdb:4QW4|rcsb pdb:4QW5|rcsb pdb:4QW6|rcsb pdb:4QW7|rcsb pdb:4QWF|rcsb pdb:4QWG|rcsb pdb:4QWI|rcsb pdb:4QWJ|rcsb pdb:4QWK|rcsb pdb:4QWL|rcsb pdb:4QWR|rcsb pdb:4QWS|rcsb pdb:4QWU|rcsb pdb:4QWX|rcsb pdb:4QXJ|rcsb pdb:4QZ0|rcsb pdb:4QZ1|rcsb pdb:4QZ2|rcsb pdb:4QZ3|rcsb pdb:4QZ4|rcsb pdb:4QZ5|rcsb pdb:4QZ6|rcsb pdb:4QZ7|rcsb pdb:4QZW|rcsb pdb:4QZX|rcsb pdb:4QZZ|rcsb pdb:4R00|rcsb pdb:4R02|rcsb pdb:4R17|rcsb pdb:4R18|rcsb pdb:4RUR|rcsb pdb:4V7O|rcsb pdb:4X6Z|rcsb pdb:4Y69|rcsb pdb:4Y6A|rcsb pdb:4Y6V|rcsb pdb:4Y6Z|rcsb pdb:4Y70|rcsb pdb:4Y74|rcsb pdb:4Y75|rcsb pdb:4Y77|rcsb pdb:4Y78|rcsb pdb:4Y7W|rcsb pdb:5LTT|rcsb pdb:5M2B|rcsb pdb:5MP9|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5NIF|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6G7F|rcsb pdb:6G8M|rcsb pdb:6G8N|rcsb pdb:6GOP|rcsb pdb:6H39|rcsb pdb:6HTB|rcsb pdb:6HTC|rcsb pdb:6HTD|rcsb pdb:6HTP|rcsb pdb:6HTR|rcsb pdb:6HUB|rcsb pdb:6HUC|rcsb pdb:6HUQ|rcsb pdb:6HUU|rcsb pdb:6HUV|rcsb pdb:6HV3|rcsb pdb:6HV4|rcsb pdb:6HV5|rcsb pdb:6HV7|rcsb pdb:6HVA|rcsb pdb:6HVR|rcsb pdb:6HVS|rcsb pdb:6HVT|rcsb pdb:6HVU|rcsb pdb:6HVV|rcsb pdb:5L5S|rcsb pdb:5L5T|rcsb pdb:5L5U|rcsb pdb:5L5V|rcsb pdb:5L5W|rcsb pdb:5L5X|rcsb pdb:5L5Y|rcsb pdb:5L5Z|rcsb pdb:5L60|rcsb pdb:5L61|rcsb pdb:5L62|rcsb pdb:5L63|rcsb pdb:5L64|rcsb pdb:5L65|rcsb pdb:5L66|rcsb pdb:5L67|rcsb pdb:5L68|rcsb pdb:5L69|rcsb pdb:5L6A|rcsb pdb:5L6B|rcsb pdb:5L6C|rcsb pdb:5LAI|rcsb pdb:5LAJ|rcsb pdb:6HVW|rcsb pdb:6HVX|rcsb pdb:6HVY|rcsb pdb:6HW0|rcsb pdb:6HW3|rcsb pdb:6HW4|rcsb pdb:6HW5|rcsb pdb:6HW6|rcsb pdb:6HW7|rcsb pdb:6HW8|rcsb pdb:6HW9|rcsb pdb:6HWA|rcsb pdb:6HWB|rcsb pdb:6HWC|rcsb pdb:6HWD|rcsb pdb:6HWE|rcsb pdb:6HWF|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2X|rcsb pdb:6J30|rcsb pdb:6ZOU|rcsb pdb:6ZP6|rcsb pdb:6ZP8|rcsb pdb:7LS5|rcsb pdb:7LS6|rcsb pdb:7LSX|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|rcsb pdb:6J2Q|refseq:NP_014045.1|sgd:S000004931|mint:P40302|dip:DIP-1528N|sgd:YMR314W(identity)	-	isoform-comment:No experimental confirmation available.	crc64:C43CBCC1C6B9E39E	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2018/04/06	rogid:ygzEQkiDJwDAMUuFQuOWsSIqwAk9606	rogid:C9GPb0JAklkBz0t/YYqRMNEiQss559292	intact-crc:7F0F9F291B732BFB|rigid:oIuyRqKqPpz576ZXWukSRwQC/v4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40302	uniprotkb:Q9H773	intact:EBI-13955|ensemblfungi:YMR314W|uniprotkb:D6W0E1	intact:EBI-723569|intact:EBI-1384169|ensembl:ENSP00000322524	psi-mi:psa6_yeast(display_long)|uniprotkb:PRE5(gene name)|psi-mi:PRE5(display_short)|uniprotkb:YMR314W(locus name)|uniprotkb:YM9924.06(orf name)|uniprotkb:Proteasome component PRE5(gene name synonym)|uniprotkb:Macropain subunit PRE5(gene name synonym)|uniprotkb:Proteinase YSCE subunit PRE5(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit PRE5(gene name synonym)	psi-mi:dctp1_human(display_long)|uniprotkb:DCTPP1(gene name)|psi-mi:DCTPP1(display_short)|uniprotkb:RS21C6(gene name synonym)|uniprotkb:CDA03(orf name)|uniprotkb:XTP3TPA(gene name synonym)|uniprotkb:Deoxycytidine-triphosphatase 1(gene name synonym)|uniprotkb:XTP3-transactivated gene A protein(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11559771|imex:IM-24995-4872	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:4Y8T|rcsb pdb:4Y8U|rcsb pdb:4Y9Y|rcsb pdb:4Y9Z|rcsb pdb:4YA0|rcsb pdb:4YA1|rcsb pdb:4YA2|rcsb pdb:4YA3|rcsb pdb:4YA4|rcsb pdb:4YA5|rcsb pdb:4Y7X|rcsb pdb:4Y7Y|rcsb pdb:4Y80|rcsb pdb:4Y81|rcsb pdb:4Y82|rcsb pdb:4Y84|rcsb pdb:4Y8G|rcsb pdb:4Y8H|rcsb pdb:4Y8I|rcsb pdb:4Y8J|rcsb pdb:4Y8K|rcsb pdb:4Y8L|rcsb pdb:4Y8M|rcsb pdb:4Y8N|rcsb pdb:4Y8O|rcsb pdb:4Y8P|rcsb pdb:4Y8Q|rcsb pdb:4Y8R|rcsb pdb:4Y8S|rcsb pdb:5FG7|rcsb pdb:5FG9|rcsb pdb:5FGA|rcsb pdb:4YA7|rcsb pdb:4YA9|rcsb pdb:4Z1L|rcsb pdb:5A5B|rcsb pdb:5AHJ|rcsb pdb:5BOU|rcsb pdb:5BXL|rcsb pdb:5BXN|rcsb pdb:5CGF|rcsb pdb:5CGG|rcsb pdb:5CGH|rcsb pdb:5CGI|rcsb pdb:5CZ4|rcsb pdb:5CZ5|rcsb pdb:5CZ6|rcsb pdb:5CZ7|rcsb pdb:5CZ8|rcsb pdb:5CZ9|rcsb pdb:5CZA|rcsb pdb:5D0S|rcsb pdb:5D0T|rcsb pdb:5D0V|rcsb pdb:5D0W|rcsb pdb:5D0X|rcsb pdb:5D0Z|rcsb pdb:5DKI|rcsb pdb:5DKJ|rcsb pdb:5FGD|rcsb pdb:3HYE|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:3MG0|rcsb pdb:3MG4|rcsb pdb:3MG6|rcsb pdb:3MG7|rcsb pdb:3MG8|rcsb pdb:3NZJ|rcsb pdb:3NZW|rcsb pdb:3NZX|rcsb pdb:3OEU|rcsb pdb:3OEV|rcsb pdb:3OKJ|rcsb pdb:3SDI|rcsb pdb:3SDK|rcsb pdb:3SHJ|rcsb pdb:3TDD|rcsb pdb:3UN4|rcsb pdb:3UN8|rcsb pdb:3WXR|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:4EU2|rcsb pdb:4FZC|rcsb pdb:4FZG|rcsb pdb:4G4S|rcsb pdb:4GK7|rcsb pdb:4HNP|rcsb pdb:4HRC|rcsb pdb:4HRD|rcsb pdb:4INR|rcsb pdb:4INT|rcsb pdb:4INU|rcsb pdb:4J70|rcsb pdb:4JSQ|rcsb pdb:4JSU|rcsb pdb:4JT0|rcsb pdb:4LQI|rcsb pdb:4LTC|rcsb pdb:4NNN|rcsb pdb:4NNW|rcsb pdb:4NO1|rcsb pdb:4NO6|rcsb pdb:4NO8|rcsb pdb:4NO9|rcsb pdb:5FGE|rcsb pdb:5FGF|rcsb pdb:5FGG|rcsb pdb:5FGH|rcsb pdb:5FGI|rcsb pdb:5FHS|rcsb pdb:5JHR|rcsb pdb:5JHS|rcsb pdb:5L52|rcsb pdb:5L54|rcsb pdb:5L55|rcsb pdb:5L5A|rcsb pdb:5L5B|rcsb pdb:5L5D|rcsb pdb:5L5E|rcsb pdb:5L5F|rcsb pdb:5L5H|rcsb pdb:5L5I|rcsb pdb:5L5J|rcsb pdb:5L5O|rcsb pdb:5L5P|rcsb pdb:5L5Q|rcsb pdb:5L5R|rcsb pdb:4Q1S|rcsb pdb:4QBY|rcsb pdb:4QLQ|rcsb pdb:4QLS|rcsb pdb:4QLT|rcsb pdb:4QLU|rcsb pdb:4QLV|rcsb pdb:4QUX|rcsb pdb:4QUY|rcsb pdb:4QV0|rcsb pdb:4QV1|rcsb pdb:4QV3|rcsb pdb:4QV4|rcsb pdb:4QV5|rcsb pdb:4QV6|rcsb pdb:4QV7|rcsb pdb:4QV8|rcsb pdb:4QV9|rcsb pdb:4QVL|ensemblfungi:YMR314W(gene)|ensemblfungi:YMR314W_mRNA(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0042175"(nuclear outer membrane-endoplasmic reticulum membrane network)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR035144|rcsb pdb:1FNT|rcsb pdb:1G0U|rcsb pdb:1G65|rcsb pdb:1JD2|rcsb pdb:1RYP|rcsb pdb:1Z7Q|rcsb pdb:2F16|rcsb pdb:2FAK|rcsb pdb:2GPL|rcsb pdb:2ZCY|rcsb pdb:3BDM|rcsb pdb:3D29|rcsb pdb:3DY3|rcsb pdb:3DY4|rcsb pdb:3E47|rcsb pdb:3GPJ|rcsb pdb:3GPT|rcsb pdb:3GPW|rcsb pdb:4QVM|rcsb pdb:4QVN|rcsb pdb:4QVP|rcsb pdb:4QVQ|rcsb pdb:4QVV|rcsb pdb:4QVW|rcsb pdb:4QVY|rcsb pdb:4QW0|rcsb pdb:4QW1|rcsb pdb:4QW3|rcsb pdb:4QW4|rcsb pdb:4QW5|rcsb pdb:4QW6|rcsb pdb:4QW7|rcsb pdb:4QWF|rcsb pdb:4QWG|rcsb pdb:4QWI|rcsb pdb:4QWJ|rcsb pdb:4QWK|rcsb pdb:4QWL|rcsb pdb:4QWR|rcsb pdb:4QWS|rcsb pdb:4QWU|rcsb pdb:4QWX|rcsb pdb:4QXJ|rcsb pdb:4QZ0|rcsb pdb:4QZ1|rcsb pdb:4QZ2|rcsb pdb:4QZ3|rcsb pdb:4QZ4|rcsb pdb:4QZ5|rcsb pdb:4QZ6|rcsb pdb:4QZ7|rcsb pdb:4QZW|rcsb pdb:4QZX|rcsb pdb:4QZZ|rcsb pdb:4R00|rcsb pdb:4R02|rcsb pdb:4R17|rcsb pdb:4R18|rcsb pdb:4RUR|rcsb pdb:4V7O|rcsb pdb:4X6Z|rcsb pdb:4Y69|rcsb pdb:4Y6A|rcsb pdb:4Y6V|rcsb pdb:4Y6Z|rcsb pdb:4Y70|rcsb pdb:4Y74|rcsb pdb:4Y75|rcsb pdb:4Y77|rcsb pdb:4Y78|rcsb pdb:4Y7W|rcsb pdb:5LTT|rcsb pdb:5M2B|rcsb pdb:5MP9|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5NIF|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6G7F|rcsb pdb:6G8M|rcsb pdb:6G8N|rcsb pdb:6GOP|rcsb pdb:6H39|rcsb pdb:6HTB|rcsb pdb:6HTC|rcsb pdb:6HTD|rcsb pdb:6HTP|rcsb pdb:6HTR|rcsb pdb:6HUB|rcsb pdb:6HUC|rcsb pdb:6HUQ|rcsb pdb:6HUU|rcsb pdb:6HUV|rcsb pdb:6HV3|rcsb pdb:6HV4|rcsb pdb:6HV5|rcsb pdb:6HV7|rcsb pdb:6HVA|rcsb pdb:6HVR|rcsb pdb:6HVS|rcsb pdb:6HVT|rcsb pdb:6HVU|rcsb pdb:6HVV|rcsb pdb:5L5S|rcsb pdb:5L5T|rcsb pdb:5L5U|rcsb pdb:5L5V|rcsb pdb:5L5W|rcsb pdb:5L5X|rcsb pdb:5L5Y|rcsb pdb:5L5Z|rcsb pdb:5L60|rcsb pdb:5L61|rcsb pdb:5L62|rcsb pdb:5L63|rcsb pdb:5L64|rcsb pdb:5L65|rcsb pdb:5L66|rcsb pdb:5L67|rcsb pdb:5L68|rcsb pdb:5L69|rcsb pdb:5L6A|rcsb pdb:5L6B|rcsb pdb:5L6C|rcsb pdb:5LAI|rcsb pdb:5LAJ|rcsb pdb:6HVW|rcsb pdb:6HVX|rcsb pdb:6HVY|rcsb pdb:6HW0|rcsb pdb:6HW3|rcsb pdb:6HW4|rcsb pdb:6HW5|rcsb pdb:6HW6|rcsb pdb:6HW7|rcsb pdb:6HW8|rcsb pdb:6HW9|rcsb pdb:6HWA|rcsb pdb:6HWB|rcsb pdb:6HWC|rcsb pdb:6HWD|rcsb pdb:6HWE|rcsb pdb:6HWF|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2X|rcsb pdb:6J30|rcsb pdb:6ZOU|rcsb pdb:6ZP6|rcsb pdb:6ZP8|rcsb pdb:7LS5|rcsb pdb:7LS6|rcsb pdb:7LSX|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|rcsb pdb:6J2Q|refseq:NP_014045.1|sgd:S000004931|mint:P40302|dip:DIP-1528N|sgd:YMR314W(identity)	refseq:NP_077001.1|ensembl:ENST00000319285(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006253"(dCTP catabolic process)|go:"GO:0009143"(nucleoside triphosphate catabolic process)|go:"GO:0032556"(pyrimidine deoxyribonucleotide binding)|go:"GO:0042262"(DNA protection)|go:"GO:0042802"(identical protein binding)|go:"GO:0047429"(nucleoside-triphosphate diphosphatase activity)|go:"GO:0047840"(dCTP diphosphatase activity)|interpro:IPR025984|mint:Q9H773|reactome:R-HSA-499943|ensembl:ENSG00000179958(gene)|entrezgene/locuslink:79077(identity)	-	crc64:C43CBCC1C6B9E39E	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:C9GPb0JAklkBz0t/YYqRMNEiQss559292	rogid:4EfV2ZU2MgDiFXShthfualZnat09606	intact-crc:EB9ABAFFAA2D48D4|rigid:mfoAdWwBictblqsBI2yhgBhCIQQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q08379	uniprotkb:P40303	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	intact:EBI-13980|ensemblfungi:YOL038W|uniprotkb:D6W229	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:psa4_yeast(display_long)|uniprotkb:PRE6(gene name)|psi-mi:PRE6(display_short)|uniprotkb:YOL038W(locus name)|uniprotkb:Proteasome component PRE6(gene name synonym)|uniprotkb:Macropain subunit PRE6(gene name synonym)|uniprotkb:Proteinase YSCE subunit PRE6(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit PRE6(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11559789|imex:IM-24995-4874	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N|entrezgene/locuslink:2801(identity)	ensemblfungi:YOL038W(gene)|ensemblfungi:YOL038W_mRNA(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0042175"(nuclear outer membrane-endoplasmic reticulum membrane network)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023332|interpro:IPR029055|rcsb pdb:1FNT|rcsb pdb:1G0U|rcsb pdb:1G65|rcsb pdb:1JD2|rcsb pdb:1RYP|rcsb pdb:1Z7Q|rcsb pdb:2F16|rcsb pdb:2FAK|rcsb pdb:2GPL|rcsb pdb:2ZCY|rcsb pdb:3BDM|rcsb pdb:3D29|rcsb pdb:3DY3|rcsb pdb:3DY4|rcsb pdb:4QZ1|rcsb pdb:4QZ2|rcsb pdb:4QZ3|rcsb pdb:4QZ4|rcsb pdb:4QZ5|rcsb pdb:4QZ6|rcsb pdb:4QZ7|rcsb pdb:4QZW|rcsb pdb:4QZX|rcsb pdb:4QZZ|rcsb pdb:4R00|rcsb pdb:4R02|rcsb pdb:4R17|rcsb pdb:4R18|rcsb pdb:4RUR|rcsb pdb:4V7O|rcsb pdb:4X6Z|rcsb pdb:4Y69|rcsb pdb:4Y6A|rcsb pdb:4Y6V|rcsb pdb:4Y6Z|rcsb pdb:4Y70|rcsb pdb:4Y74|rcsb pdb:4Y75|rcsb pdb:4Y77|rcsb pdb:4Y78|rcsb pdb:4Y7W|rcsb pdb:4Y7X|rcsb pdb:4Y7Y|rcsb pdb:4Y80|rcsb pdb:4QZ0|rcsb pdb:4Y81|rcsb pdb:4Y82|rcsb pdb:4Y84|rcsb pdb:4Y8H|rcsb pdb:4Y8I|rcsb pdb:4Y8J|rcsb pdb:4Y8K|rcsb pdb:4Y8L|rcsb pdb:4Y8M|rcsb pdb:4Y8N|rcsb pdb:4Y8O|rcsb pdb:4Y8P|rcsb pdb:4Y8Q|rcsb pdb:4Y8R|rcsb pdb:4Y8S|rcsb pdb:4Y8T|rcsb pdb:4Y8U|rcsb pdb:4Y9Y|rcsb pdb:4Y9Z|rcsb pdb:4YA0|rcsb pdb:4YA1|rcsb pdb:4YA2|rcsb pdb:4YA3|rcsb pdb:4Y8G|rcsb pdb:4YA4|rcsb pdb:4YA5|rcsb pdb:4YA7|rcsb pdb:4YA9|rcsb pdb:4Z1L|rcsb pdb:5A5B|rcsb pdb:5AHJ|rcsb pdb:5BOU|rcsb pdb:5BXN|rcsb pdb:5CGF|rcsb pdb:5CGG|rcsb pdb:5CGH|rcsb pdb:5CGI|rcsb pdb:5CZ4|rcsb pdb:5CZ5|rcsb pdb:5CZ6|rcsb pdb:5CZ7|rcsb pdb:5CZ8|rcsb pdb:5CZ9|rcsb pdb:5CZA|rcsb pdb:5D0S|rcsb pdb:5D0T|rcsb pdb:5D0V|rcsb pdb:5D0W|rcsb pdb:5D0X|rcsb pdb:5BXL|rcsb pdb:5D0Z|rcsb pdb:5DKI|rcsb pdb:5DKJ|rcsb pdb:5FG9|rcsb pdb:5FGA|rcsb pdb:5FGD|rcsb pdb:5FGE|rcsb pdb:5FGF|rcsb pdb:5FGG|rcsb pdb:5FGH|rcsb pdb:5FG7|rcsb pdb:5FGI|rcsb pdb:5FHS|rcsb pdb:5JHR|rcsb pdb:5JHS|rcsb pdb:5L52|rcsb pdb:5L54|rcsb pdb:5L55|rcsb pdb:5L5A|rcsb pdb:5L5B|rcsb pdb:5L5D|rcsb pdb:5L5E|rcsb pdb:5L5F|rcsb pdb:5L5H|rcsb pdb:5L5I|rcsb pdb:5L5J|rcsb pdb:5L5O|rcsb pdb:5L5P|rcsb pdb:5L5Q|rcsb pdb:5L5R|rcsb pdb:5L5S|rcsb pdb:5L5T|rcsb pdb:5L5U|rcsb pdb:5L5V|rcsb pdb:5L5W|rcsb pdb:5L5X|rcsb pdb:5L5Y|rcsb pdb:5L5Z|rcsb pdb:5L60|rcsb pdb:5L61|rcsb pdb:5L62|rcsb pdb:5L63|rcsb pdb:5L64|rcsb pdb:5L65|rcsb pdb:5L66|rcsb pdb:5L67|rcsb pdb:5L68|rcsb pdb:5L69|rcsb pdb:5L6A|rcsb pdb:5L6B|rcsb pdb:5LAI|rcsb pdb:5LAJ|rcsb pdb:5LTT|rcsb pdb:5M2B|rcsb pdb:5MP9|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5NIF|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:5L6C|rcsb pdb:6FVW|rcsb pdb:6FVY|rcsb pdb:6G7F|rcsb pdb:6G8M|rcsb pdb:6G8N|rcsb pdb:6GOP|rcsb pdb:6H39|rcsb pdb:6HTB|rcsb pdb:6HTC|rcsb pdb:6HTD|rcsb pdb:6HTP|rcsb pdb:6HTR|rcsb pdb:6HUB|rcsb pdb:6HUC|rcsb pdb:6HUQ|rcsb pdb:6FVX|rcsb pdb:6HUU|rcsb pdb:6HUV|rcsb pdb:6HV3|rcsb pdb:6HV4|rcsb pdb:6HV5|rcsb pdb:6HV7|rcsb pdb:6HVA|rcsb pdb:6HVR|rcsb pdb:6HVS|rcsb pdb:6HVT|rcsb pdb:6HVU|rcsb pdb:6HVV|rcsb pdb:6HVW|rcsb pdb:6HVX|rcsb pdb:6HVY|rcsb pdb:6HW0|rcsb pdb:6HW3|rcsb pdb:6HW4|rcsb pdb:6HW5|rcsb pdb:6HW6|rcsb pdb:6HW7|rcsb pdb:6HW8|rcsb pdb:6HW9|rcsb pdb:6HWA|rcsb pdb:6HWB|rcsb pdb:6HWC|rcsb pdb:6HWE|rcsb pdb:6HWF|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6HWD|rcsb pdb:6J2X|rcsb pdb:6J30|rcsb pdb:6ZOU|rcsb pdb:6ZP6|rcsb pdb:6ZP8|rcsb pdb:7LS5|rcsb pdb:7LS6|rcsb pdb:7LSX|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|rcsb pdb:3E47|rcsb pdb:3GPJ|rcsb pdb:3GPT|rcsb pdb:3GPW|rcsb pdb:3HYE|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:3MG0|rcsb pdb:3MG4|rcsb pdb:3MG6|rcsb pdb:3MG7|rcsb pdb:3MG8|rcsb pdb:3NZJ|rcsb pdb:3NZW|rcsb pdb:3NZX|rcsb pdb:3OEU|rcsb pdb:3OEV|rcsb pdb:3OKJ|rcsb pdb:3SDI|rcsb pdb:3SDK|rcsb pdb:3SHJ|rcsb pdb:3TDD|rcsb pdb:3UN4|rcsb pdb:3UN8|rcsb pdb:3WXR|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:4EU2|rcsb pdb:4FZC|rcsb pdb:4FZG|rcsb pdb:4G4S|rcsb pdb:4GK7|rcsb pdb:4HRC|rcsb pdb:4HRD|rcsb pdb:4INR|rcsb pdb:4INT|rcsb pdb:4INU|rcsb pdb:4J70|rcsb pdb:4JSQ|rcsb pdb:4JSU|rcsb pdb:4JT0|rcsb pdb:4LQI|rcsb pdb:4LTC|rcsb pdb:4NNN|rcsb pdb:4NNW|rcsb pdb:4NO1|rcsb pdb:4HNP|rcsb pdb:4NO6|rcsb pdb:4NO8|rcsb pdb:4NO9|rcsb pdb:4Q1S|rcsb pdb:4QBY|rcsb pdb:4QLQ|rcsb pdb:4QLS|rcsb pdb:4QLT|rcsb pdb:4QLU|rcsb pdb:4QLV|rcsb pdb:4QUX|rcsb pdb:4QUY|rcsb pdb:4QV1|rcsb pdb:4QV3|rcsb pdb:4QV4|rcsb pdb:4QV5|rcsb pdb:4QV6|rcsb pdb:4QV7|rcsb pdb:4QV8|rcsb pdb:4QV9|rcsb pdb:4QVL|rcsb pdb:4QVM|rcsb pdb:4QVN|rcsb pdb:4QVP|rcsb pdb:4QVQ|rcsb pdb:4QVV|rcsb pdb:4QVW|rcsb pdb:4QVY|rcsb pdb:4QW0|rcsb pdb:4QW1|rcsb pdb:4QW3|rcsb pdb:4QW4|rcsb pdb:4QW5|rcsb pdb:4QW6|rcsb pdb:4QW7|rcsb pdb:4QWF|rcsb pdb:4QWG|rcsb pdb:4QV0|rcsb pdb:4QWI|rcsb pdb:4QWJ|rcsb pdb:4QWK|rcsb pdb:4QWL|rcsb pdb:4QWR|rcsb pdb:4QWS|rcsb pdb:4QWU|rcsb pdb:4QWX|rcsb pdb:4QXJ|refseq:NP_014604.1|sgd:S000005398|mint:P40303|dip:DIP-4844N|sgd:YOL038W(identity)	-	-	crc64:73AEE63B836E618A	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2017/05/26	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	rogid:G8IQr0G8FhiWc0DYUlh3vecHQsU559292	intact-crc:B69FFF6044F53910|rigid:ISh8x9sKRumZ+m46aodWbR7ddg8	false	sufficient binding region:383-1002	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40302	uniprotkb:Q9NSC5	intact:EBI-13955|ensemblfungi:YMR314W|uniprotkb:D6W0E1	intact:EBI-748420|uniprotkb:O14580|uniprotkb:O95350|uniprotkb:Q9NSB9|uniprotkb:Q9NSC0|intact:EBI-2557809|uniprotkb:E9PCW9|uniprotkb:Q9NSC1|intact:EBI-28972925|ensembl:ENSP00000376162|ensembl:ENSP00000439937|ensembl:ENSP00000446026|intact:EBI-10175777|uniprotkb:B2RA10	psi-mi:psa6_yeast(display_long)|uniprotkb:PRE5(gene name)|psi-mi:PRE5(display_short)|uniprotkb:YMR314W(locus name)|uniprotkb:YM9924.06(orf name)|uniprotkb:Proteasome component PRE5(gene name synonym)|uniprotkb:Macropain subunit PRE5(gene name synonym)|uniprotkb:Proteinase YSCE subunit PRE5(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit PRE5(gene name synonym)	psi-mi:home3_human(display_long)|uniprotkb:HOMER3(gene name)|psi-mi:HOMER3(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11559780|imex:IM-24995-4873	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:4Y8T|rcsb pdb:4Y8U|rcsb pdb:4Y9Y|rcsb pdb:4Y9Z|rcsb pdb:4YA0|rcsb pdb:4YA1|rcsb pdb:4YA2|rcsb pdb:4YA3|rcsb pdb:4YA4|rcsb pdb:4YA5|rcsb pdb:4Y7X|rcsb pdb:4Y7Y|rcsb pdb:4Y80|rcsb pdb:4Y81|rcsb pdb:4Y82|rcsb pdb:4Y84|rcsb pdb:4Y8G|rcsb pdb:4Y8H|rcsb pdb:4Y8I|rcsb pdb:4Y8J|rcsb pdb:4Y8K|rcsb pdb:4Y8L|rcsb pdb:4Y8M|rcsb pdb:4Y8N|rcsb pdb:4Y8O|rcsb pdb:4Y8P|rcsb pdb:4Y8Q|rcsb pdb:4Y8R|rcsb pdb:4Y8S|rcsb pdb:5FG7|rcsb pdb:5FG9|rcsb pdb:5FGA|rcsb pdb:4YA7|rcsb pdb:4YA9|rcsb pdb:4Z1L|rcsb pdb:5A5B|rcsb pdb:5AHJ|rcsb pdb:5BOU|rcsb pdb:5BXL|rcsb pdb:5BXN|rcsb pdb:5CGF|rcsb pdb:5CGG|rcsb pdb:5CGH|rcsb pdb:5CGI|rcsb pdb:5CZ4|rcsb pdb:5CZ5|rcsb pdb:5CZ6|rcsb pdb:5CZ7|rcsb pdb:5CZ8|rcsb pdb:5CZ9|rcsb pdb:5CZA|rcsb pdb:5D0S|rcsb pdb:5D0T|rcsb pdb:5D0V|rcsb pdb:5D0W|rcsb pdb:5D0X|rcsb pdb:5D0Z|rcsb pdb:5DKI|rcsb pdb:5DKJ|rcsb pdb:5FGD|rcsb pdb:3HYE|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:3MG0|rcsb pdb:3MG4|rcsb pdb:3MG6|rcsb pdb:3MG7|rcsb pdb:3MG8|rcsb pdb:3NZJ|rcsb pdb:3NZW|rcsb pdb:3NZX|rcsb pdb:3OEU|rcsb pdb:3OEV|rcsb pdb:3OKJ|rcsb pdb:3SDI|rcsb pdb:3SDK|rcsb pdb:3SHJ|rcsb pdb:3TDD|rcsb pdb:3UN4|rcsb pdb:3UN8|rcsb pdb:3WXR|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:4EU2|rcsb pdb:4FZC|rcsb pdb:4FZG|rcsb pdb:4G4S|rcsb pdb:4GK7|rcsb pdb:4HNP|rcsb pdb:4HRC|rcsb pdb:4HRD|rcsb pdb:4INR|rcsb pdb:4INT|rcsb pdb:4INU|rcsb pdb:4J70|rcsb pdb:4JSQ|rcsb pdb:4JSU|rcsb pdb:4JT0|rcsb pdb:4LQI|rcsb pdb:4LTC|rcsb pdb:4NNN|rcsb pdb:4NNW|rcsb pdb:4NO1|rcsb pdb:4NO6|rcsb pdb:4NO8|rcsb pdb:4NO9|rcsb pdb:5FGE|rcsb pdb:5FGF|rcsb pdb:5FGG|rcsb pdb:5FGH|rcsb pdb:5FGI|rcsb pdb:5FHS|rcsb pdb:5JHR|rcsb pdb:5JHS|rcsb pdb:5L52|rcsb pdb:5L54|rcsb pdb:5L55|rcsb pdb:5L5A|rcsb pdb:5L5B|rcsb pdb:5L5D|rcsb pdb:5L5E|rcsb pdb:5L5F|rcsb pdb:5L5H|rcsb pdb:5L5I|rcsb pdb:5L5J|rcsb pdb:5L5O|rcsb pdb:5L5P|rcsb pdb:5L5Q|rcsb pdb:5L5R|rcsb pdb:4Q1S|rcsb pdb:4QBY|rcsb pdb:4QLQ|rcsb pdb:4QLS|rcsb pdb:4QLT|rcsb pdb:4QLU|rcsb pdb:4QLV|rcsb pdb:4QUX|rcsb pdb:4QUY|rcsb pdb:4QV0|rcsb pdb:4QV1|rcsb pdb:4QV3|rcsb pdb:4QV4|rcsb pdb:4QV5|rcsb pdb:4QV6|rcsb pdb:4QV7|rcsb pdb:4QV8|rcsb pdb:4QV9|rcsb pdb:4QVL|ensemblfungi:YMR314W(gene)|ensemblfungi:YMR314W_mRNA(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0042175"(nuclear outer membrane-endoplasmic reticulum membrane network)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR035144|rcsb pdb:1FNT|rcsb pdb:1G0U|rcsb pdb:1G65|rcsb pdb:1JD2|rcsb pdb:1RYP|rcsb pdb:1Z7Q|rcsb pdb:2F16|rcsb pdb:2FAK|rcsb pdb:2GPL|rcsb pdb:2ZCY|rcsb pdb:3BDM|rcsb pdb:3D29|rcsb pdb:3DY3|rcsb pdb:3DY4|rcsb pdb:3E47|rcsb pdb:3GPJ|rcsb pdb:3GPT|rcsb pdb:3GPW|rcsb pdb:4QVM|rcsb pdb:4QVN|rcsb pdb:4QVP|rcsb pdb:4QVQ|rcsb pdb:4QVV|rcsb pdb:4QVW|rcsb pdb:4QVY|rcsb pdb:4QW0|rcsb pdb:4QW1|rcsb pdb:4QW3|rcsb pdb:4QW4|rcsb pdb:4QW5|rcsb pdb:4QW6|rcsb pdb:4QW7|rcsb pdb:4QWF|rcsb pdb:4QWG|rcsb pdb:4QWI|rcsb pdb:4QWJ|rcsb pdb:4QWK|rcsb pdb:4QWL|rcsb pdb:4QWR|rcsb pdb:4QWS|rcsb pdb:4QWU|rcsb pdb:4QWX|rcsb pdb:4QXJ|rcsb pdb:4QZ0|rcsb pdb:4QZ1|rcsb pdb:4QZ2|rcsb pdb:4QZ3|rcsb pdb:4QZ4|rcsb pdb:4QZ5|rcsb pdb:4QZ6|rcsb pdb:4QZ7|rcsb pdb:4QZW|rcsb pdb:4QZX|rcsb pdb:4QZZ|rcsb pdb:4R00|rcsb pdb:4R02|rcsb pdb:4R17|rcsb pdb:4R18|rcsb pdb:4RUR|rcsb pdb:4V7O|rcsb pdb:4X6Z|rcsb pdb:4Y69|rcsb pdb:4Y6A|rcsb pdb:4Y6V|rcsb pdb:4Y6Z|rcsb pdb:4Y70|rcsb pdb:4Y74|rcsb pdb:4Y75|rcsb pdb:4Y77|rcsb pdb:4Y78|rcsb pdb:4Y7W|rcsb pdb:5LTT|rcsb pdb:5M2B|rcsb pdb:5MP9|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5NIF|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6G7F|rcsb pdb:6G8M|rcsb pdb:6G8N|rcsb pdb:6GOP|rcsb pdb:6H39|rcsb pdb:6HTB|rcsb pdb:6HTC|rcsb pdb:6HTD|rcsb pdb:6HTP|rcsb pdb:6HTR|rcsb pdb:6HUB|rcsb pdb:6HUC|rcsb pdb:6HUQ|rcsb pdb:6HUU|rcsb pdb:6HUV|rcsb pdb:6HV3|rcsb pdb:6HV4|rcsb pdb:6HV5|rcsb pdb:6HV7|rcsb pdb:6HVA|rcsb pdb:6HVR|rcsb pdb:6HVS|rcsb pdb:6HVT|rcsb pdb:6HVU|rcsb pdb:6HVV|rcsb pdb:5L5S|rcsb pdb:5L5T|rcsb pdb:5L5U|rcsb pdb:5L5V|rcsb pdb:5L5W|rcsb pdb:5L5X|rcsb pdb:5L5Y|rcsb pdb:5L5Z|rcsb pdb:5L60|rcsb pdb:5L61|rcsb pdb:5L62|rcsb pdb:5L63|rcsb pdb:5L64|rcsb pdb:5L65|rcsb pdb:5L66|rcsb pdb:5L67|rcsb pdb:5L68|rcsb pdb:5L69|rcsb pdb:5L6A|rcsb pdb:5L6B|rcsb pdb:5L6C|rcsb pdb:5LAI|rcsb pdb:5LAJ|rcsb pdb:6HVW|rcsb pdb:6HVX|rcsb pdb:6HVY|rcsb pdb:6HW0|rcsb pdb:6HW3|rcsb pdb:6HW4|rcsb pdb:6HW5|rcsb pdb:6HW6|rcsb pdb:6HW7|rcsb pdb:6HW8|rcsb pdb:6HW9|rcsb pdb:6HWA|rcsb pdb:6HWB|rcsb pdb:6HWC|rcsb pdb:6HWD|rcsb pdb:6HWE|rcsb pdb:6HWF|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2X|rcsb pdb:6J30|rcsb pdb:6ZOU|rcsb pdb:6ZP6|rcsb pdb:6ZP8|rcsb pdb:7LS5|rcsb pdb:7LS6|rcsb pdb:7LSX|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|rcsb pdb:6J2Q|refseq:NP_014045.1|sgd:S000004931|mint:P40302|dip:DIP-1528N|sgd:YMR314W(identity)	ensembl:ENST00000221222|ensembl:ENSP00000221222|ensembl:ENSP00000376162|ensembl:ENST00000433218|ensembl:ENSP00000396154|ensembl:ENSP00000439937|ensembl:ENSP00000446026|ensembl:ENST00000594439|ensembl:ENSP00000471835|refseq:XP_006723006.1|refseq:XP_006723007.1|refseq:NP_001139193.1|refseq:NP_001139194.1|refseq:NP_004829.3|refseq:NP_001139196.1|ensembl:ENSG00000051128(gene)|ensembl:ENST00000392351(transcript)|ensembl:ENST00000539827(transcript)|ensembl:ENST00000542541(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006605"(protein targeting)|go:"GO:0007216"(G protein-coupled glutamate receptor signaling pathway)|go:"GO:0014069"(postsynaptic density)|go:"GO:0030425"(dendrite)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0035256"(G protein-coupled glutamate receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|go:"GO:2001256"(regulation of store-operated calcium entry)|interpro:IPR000697(EVH1)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR044100|mint:Q9NSC5|rcsb pdb:2P8V|rcsb pdb:3CVF|reactome:R-HSA-6794361|entrezgene/locuslink:9454(identity)	-	crc64:C43CBCC1C6B9E39E	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:C9GPb0JAklkBz0t/YYqRMNEiQss559292	rogid:U1y/y52nnf7zQUCNQlqk7JDgXi49606	intact-crc:CCD63EBA4AB35BB1|rigid:xJu4udRnt8uJIyFOJNW18Br9+yU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40303	uniprotkb:Q8NEU8	intact:EBI-13980|ensemblfungi:YOL038W|uniprotkb:D6W229	intact:EBI-741261|ensembl:ENSP00000258530|uniprotkb:Q8N4R7|uniprotkb:Q9NVL2|uniprotkb:B7Z411|uniprotkb:B7Z4B0|uniprotkb:F5GZG0|uniprotkb:F8W1P5	psi-mi:psa4_yeast(display_long)|uniprotkb:PRE6(gene name)|psi-mi:PRE6(display_short)|uniprotkb:YOL038W(locus name)|uniprotkb:Proteasome component PRE6(gene name synonym)|uniprotkb:Macropain subunit PRE6(gene name synonym)|uniprotkb:Proteinase YSCE subunit PRE6(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit PRE6(gene name synonym)	psi-mi:dp13b_human(display_long)|uniprotkb:Adapter protein containing PH domain, PTB domain and leucine zipper motif 2(gene name synonym)|uniprotkb:APPL2(gene name)|psi-mi:APPL2(display_short)|uniprotkb:DIP13B(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11559800|imex:IM-24995-4875	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YOL038W(gene)|ensemblfungi:YOL038W_mRNA(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0042175"(nuclear outer membrane-endoplasmic reticulum membrane network)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023332|interpro:IPR029055|rcsb pdb:1FNT|rcsb pdb:1G0U|rcsb pdb:1G65|rcsb pdb:1JD2|rcsb pdb:1RYP|rcsb pdb:1Z7Q|rcsb pdb:2F16|rcsb pdb:2FAK|rcsb pdb:2GPL|rcsb pdb:2ZCY|rcsb pdb:3BDM|rcsb pdb:3D29|rcsb pdb:3DY3|rcsb pdb:3DY4|rcsb pdb:4QZ1|rcsb pdb:4QZ2|rcsb pdb:4QZ3|rcsb pdb:4QZ4|rcsb pdb:4QZ5|rcsb pdb:4QZ6|rcsb pdb:4QZ7|rcsb pdb:4QZW|rcsb pdb:4QZX|rcsb pdb:4QZZ|rcsb pdb:4R00|rcsb pdb:4R02|rcsb pdb:4R17|rcsb pdb:4R18|rcsb pdb:4RUR|rcsb pdb:4V7O|rcsb pdb:4X6Z|rcsb pdb:4Y69|rcsb pdb:4Y6A|rcsb pdb:4Y6V|rcsb pdb:4Y6Z|rcsb pdb:4Y70|rcsb pdb:4Y74|rcsb pdb:4Y75|rcsb pdb:4Y77|rcsb pdb:4Y78|rcsb pdb:4Y7W|rcsb pdb:4Y7X|rcsb pdb:4Y7Y|rcsb pdb:4Y80|rcsb pdb:4QZ0|rcsb pdb:4Y81|rcsb pdb:4Y82|rcsb pdb:4Y84|rcsb pdb:4Y8H|rcsb pdb:4Y8I|rcsb pdb:4Y8J|rcsb pdb:4Y8K|rcsb pdb:4Y8L|rcsb pdb:4Y8M|rcsb pdb:4Y8N|rcsb pdb:4Y8O|rcsb pdb:4Y8P|rcsb pdb:4Y8Q|rcsb pdb:4Y8R|rcsb pdb:4Y8S|rcsb pdb:4Y8T|rcsb pdb:4Y8U|rcsb pdb:4Y9Y|rcsb pdb:4Y9Z|rcsb pdb:4YA0|rcsb pdb:4YA1|rcsb pdb:4YA2|rcsb pdb:4YA3|rcsb pdb:4Y8G|rcsb pdb:4YA4|rcsb pdb:4YA5|rcsb pdb:4YA7|rcsb pdb:4YA9|rcsb pdb:4Z1L|rcsb pdb:5A5B|rcsb pdb:5AHJ|rcsb pdb:5BOU|rcsb pdb:5BXN|rcsb pdb:5CGF|rcsb pdb:5CGG|rcsb pdb:5CGH|rcsb pdb:5CGI|rcsb pdb:5CZ4|rcsb pdb:5CZ5|rcsb pdb:5CZ6|rcsb pdb:5CZ7|rcsb pdb:5CZ8|rcsb pdb:5CZ9|rcsb pdb:5CZA|rcsb pdb:5D0S|rcsb pdb:5D0T|rcsb pdb:5D0V|rcsb pdb:5D0W|rcsb pdb:5D0X|rcsb pdb:5BXL|rcsb pdb:5D0Z|rcsb pdb:5DKI|rcsb pdb:5DKJ|rcsb pdb:5FG9|rcsb pdb:5FGA|rcsb pdb:5FGD|rcsb pdb:5FGE|rcsb pdb:5FGF|rcsb pdb:5FGG|rcsb pdb:5FGH|rcsb pdb:5FG7|rcsb pdb:5FGI|rcsb pdb:5FHS|rcsb pdb:5JHR|rcsb pdb:5JHS|rcsb pdb:5L52|rcsb pdb:5L54|rcsb pdb:5L55|rcsb pdb:5L5A|rcsb pdb:5L5B|rcsb pdb:5L5D|rcsb pdb:5L5E|rcsb pdb:5L5F|rcsb pdb:5L5H|rcsb pdb:5L5I|rcsb pdb:5L5J|rcsb pdb:5L5O|rcsb pdb:5L5P|rcsb pdb:5L5Q|rcsb pdb:5L5R|rcsb pdb:5L5S|rcsb pdb:5L5T|rcsb pdb:5L5U|rcsb pdb:5L5V|rcsb pdb:5L5W|rcsb pdb:5L5X|rcsb pdb:5L5Y|rcsb pdb:5L5Z|rcsb pdb:5L60|rcsb pdb:5L61|rcsb pdb:5L62|rcsb pdb:5L63|rcsb pdb:5L64|rcsb pdb:5L65|rcsb pdb:5L66|rcsb pdb:5L67|rcsb pdb:5L68|rcsb pdb:5L69|rcsb pdb:5L6A|rcsb pdb:5L6B|rcsb pdb:5LAI|rcsb pdb:5LAJ|rcsb pdb:5LTT|rcsb pdb:5M2B|rcsb pdb:5MP9|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5NIF|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:5L6C|rcsb pdb:6FVW|rcsb pdb:6FVY|rcsb pdb:6G7F|rcsb pdb:6G8M|rcsb pdb:6G8N|rcsb pdb:6GOP|rcsb pdb:6H39|rcsb pdb:6HTB|rcsb pdb:6HTC|rcsb pdb:6HTD|rcsb pdb:6HTP|rcsb pdb:6HTR|rcsb pdb:6HUB|rcsb pdb:6HUC|rcsb pdb:6HUQ|rcsb pdb:6FVX|rcsb pdb:6HUU|rcsb pdb:6HUV|rcsb pdb:6HV3|rcsb pdb:6HV4|rcsb pdb:6HV5|rcsb pdb:6HV7|rcsb pdb:6HVA|rcsb pdb:6HVR|rcsb pdb:6HVS|rcsb pdb:6HVT|rcsb pdb:6HVU|rcsb pdb:6HVV|rcsb pdb:6HVW|rcsb pdb:6HVX|rcsb pdb:6HVY|rcsb pdb:6HW0|rcsb pdb:6HW3|rcsb pdb:6HW4|rcsb pdb:6HW5|rcsb pdb:6HW6|rcsb pdb:6HW7|rcsb pdb:6HW8|rcsb pdb:6HW9|rcsb pdb:6HWA|rcsb pdb:6HWB|rcsb pdb:6HWC|rcsb pdb:6HWE|rcsb pdb:6HWF|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6HWD|rcsb pdb:6J2X|rcsb pdb:6J30|rcsb pdb:6ZOU|rcsb pdb:6ZP6|rcsb pdb:6ZP8|rcsb pdb:7LS5|rcsb pdb:7LS6|rcsb pdb:7LSX|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|rcsb pdb:3E47|rcsb pdb:3GPJ|rcsb pdb:3GPT|rcsb pdb:3GPW|rcsb pdb:3HYE|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:3MG0|rcsb pdb:3MG4|rcsb pdb:3MG6|rcsb pdb:3MG7|rcsb pdb:3MG8|rcsb pdb:3NZJ|rcsb pdb:3NZW|rcsb pdb:3NZX|rcsb pdb:3OEU|rcsb pdb:3OEV|rcsb pdb:3OKJ|rcsb pdb:3SDI|rcsb pdb:3SDK|rcsb pdb:3SHJ|rcsb pdb:3TDD|rcsb pdb:3UN4|rcsb pdb:3UN8|rcsb pdb:3WXR|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:4EU2|rcsb pdb:4FZC|rcsb pdb:4FZG|rcsb pdb:4G4S|rcsb pdb:4GK7|rcsb pdb:4HRC|rcsb pdb:4HRD|rcsb pdb:4INR|rcsb pdb:4INT|rcsb pdb:4INU|rcsb pdb:4J70|rcsb pdb:4JSQ|rcsb pdb:4JSU|rcsb pdb:4JT0|rcsb pdb:4LQI|rcsb pdb:4LTC|rcsb pdb:4NNN|rcsb pdb:4NNW|rcsb pdb:4NO1|rcsb pdb:4HNP|rcsb pdb:4NO6|rcsb pdb:4NO8|rcsb pdb:4NO9|rcsb pdb:4Q1S|rcsb pdb:4QBY|rcsb pdb:4QLQ|rcsb pdb:4QLS|rcsb pdb:4QLT|rcsb pdb:4QLU|rcsb pdb:4QLV|rcsb pdb:4QUX|rcsb pdb:4QUY|rcsb pdb:4QV1|rcsb pdb:4QV3|rcsb pdb:4QV4|rcsb pdb:4QV5|rcsb pdb:4QV6|rcsb pdb:4QV7|rcsb pdb:4QV8|rcsb pdb:4QV9|rcsb pdb:4QVL|rcsb pdb:4QVM|rcsb pdb:4QVN|rcsb pdb:4QVP|rcsb pdb:4QVQ|rcsb pdb:4QVV|rcsb pdb:4QVW|rcsb pdb:4QVY|rcsb pdb:4QW0|rcsb pdb:4QW1|rcsb pdb:4QW3|rcsb pdb:4QW4|rcsb pdb:4QW5|rcsb pdb:4QW6|rcsb pdb:4QW7|rcsb pdb:4QWF|rcsb pdb:4QWG|rcsb pdb:4QV0|rcsb pdb:4QWI|rcsb pdb:4QWJ|rcsb pdb:4QWK|rcsb pdb:4QWL|rcsb pdb:4QWR|rcsb pdb:4QWS|rcsb pdb:4QWU|rcsb pdb:4QWX|rcsb pdb:4QXJ|refseq:NP_014604.1|sgd:S000005398|mint:P40303|dip:DIP-4844N|sgd:YOL038W(identity)	go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0002024"(diet induced thermogenesis)|go:"GO:0005634"(nucleus)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0009631"(cold acclimation)|go:"GO:0010008"(endosome membrane)|go:"GO:0010762"(regulation of fibroblast migration)|go:"GO:0016020"(membrane)|go:"GO:0023052"(signaling)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032009"(early phagosome)|go:"GO:0032587"(ruffle membrane)|go:"GO:0033211"(adiponectin-activated signaling pathway)|go:"GO:0034143"(regulation of toll-like receptor 4 signaling pathway)|go:"GO:0035091"(phosphatidylinositol binding)|ensembl:ENSG00000136044(gene)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0036186"(early phagosome membrane)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|ensembl:ENST00000258530(transcript)|go:"GO:0044354"(macropinosome)|go:"GO:0001726"(ruffle)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000178"(negative regulation of neural precursor cell proliferation)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR027267|mint:Q8NEU8|rcsb pdb:4H8S|rcsb pdb:5C5B|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0046322"(negative regulation of fatty acid oxidation)|go:"GO:0046325"(negative regulation of glucose import)|go:"GO:0050768"(negative regulation of neurogenesis)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060100"(positive regulation of phagocytosis, engulfment)|go:"GO:0070062"(extracellular exosome)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1900016"(negative regulation of cytokine production involved in inflammatory response)|go:"GO:1900077"(negative regulation of cellular response to insulin stimulus)|go:"GO:1905303"(positive regulation of macropinocytosis)|go:"GO:1905451"(positive regulation of Fc-gamma receptor signaling pathway involved in phagocytosis)|refseq:NP_060641.2|refseq:XP_016875042.1|refseq:XP_016875041.1|refseq:NP_001238833.1|refseq:NP_001238834.1|entrezgene/locuslink:55198(identity)	-	crc64:73AEE63B836E618A	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:G8IQr0G8FhiWc0DYUlh3vecHQsU559292	rogid:8T+Y5phqYZ2On/CsfVVsOChSJNM9606	intact-crc:203737DE6F0937B2|rigid:tKdwVIRRkDlkwHnZtCmlUdnHbM4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40325	uniprotkb:E9PFK9	intact:EBI-23614|uniprotkb:D6VV46|ensemblfungi:YGR268C	intact:EBI-11523104|ensembl:ENSP00000403429	psi-mi:hua1_yeast(display_long)|uniprotkb:HUA1(gene name)|psi-mi:HUA1(display_short)|uniprotkb:YGR268C(locus name)	psi-mi:e9pfk9_human(display_long)|uniprotkb:RABGEF1(gene name)|psi-mi:RABGEF1(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11559818|imex:IM-24995-4877	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003500|refseq:NP_011784.3|dip:DIP-1987N|ensemblfungi:YGR268C(gene)|ensemblfungi:YGR268C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|interpro:IPR038910|sgd:YGR268C(identity)	ensembl:ENSG00000154710(gene)|ensembl:ENST00000439720(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|interpro:IPR002653(Zinc finger, A20-type)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR037191|interpro:IPR041545|entrezgene/locuslink:27342(identity)	-	crc64:78029FD484168793	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:xliNG9XUWbYRd0Nbu+xzCgxNrAs559292	rogid:JDHW8cuCB2z39j6a+LlkARnLfYo9606	intact-crc:DD596A52A76FD8F8|rigid:HAvEPRZLIiZozCqVw7mjCvpShpU	false	-	sufficient binding region:14-504	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8N6L0	uniprotkb:P40312	intact:EBI-749265|uniprotkb:Q96MC3|ensembl:ENSP00000404220	intact:EBI-2095239|uniprotkb:D6W170|ensemblfungi:YNL111C	psi-mi:kash5_human(display_long)|uniprotkb:KASH5(gene name)|psi-mi:KASH5(display_short)|uniprotkb:CCDC155(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 155(gene name synonym)|uniprotkb:KASH domain-containing protein 5(gene name synonym)	psi-mi:cyb5_yeast(display_long)|uniprotkb:N1949(orf name)|uniprotkb:YNL111C(locus name)|uniprotkb:CYB5(gene name)|psi-mi:CYB5(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11559809|imex:IM-24995-4876	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_653289.3|ensembl:ENSG00000161609(gene)|ensembl:ENST00000447857(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034397"(telomere localization)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051225"(spindle assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0090172"(microtubule cytoskeleton organization involved in homologous chromosome segregation)|go:"GO:0090220"(chromosome localization to nuclear envelope involved in homologous chromosome segregation)|go:"GO:0090619"(meiotic spindle pole)|interpro:IPR011992(EF-Hand type)|interpro:IPR028168|interpro:IPR028170|interpro:IPR039508|mint:Q8N6L0|rcsb pdb:6R2I|rcsb pdb:6WMF|entrezgene/locuslink:147872(identity)	sgd:S000005055|interpro:IPR001199(Cytochrome b5)|interpro:IPR018506|refseq:NP_014288.3|mint:P40312|interpro:IPR036400|ensemblfungi:YNL111C(gene)|ensemblfungi:YNL111C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0009055"(electron transfer activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016126"(sterol biosynthetic process)|go:"GO:0020037"(heme binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|reactome:R-SCE-196836|reactome:R-SCE-9609523|sgd:YNL111C(identity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Wl9L7AcvDHCZuKjYLn8QgGIbZTc9606	rogid:aB5Ul8scxDg0gRGx3rkZwTtfNM4559292	intact-crc:4C1974419884CC6B|rigid:8eqAa6AQQ/XG1Q8umWLNxw2xuiw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O00308	uniprotkb:P40325	intact:EBI-743923|uniprotkb:H3BRF3|uniprotkb:Q6ZTQ5|uniprotkb:A6NEP1|uniprotkb:Q96CZ2|uniprotkb:Q9BWN6|uniprotkb:B2R706|uniprotkb:B4DTL5|uniprotkb:F5H213|uniprotkb:I3RSG8|ensembl:ENSP00000352069	intact:EBI-23614|uniprotkb:D6VV46|ensemblfungi:YGR268C	psi-mi:wwp2_human(display_long)|uniprotkb:WW domain-containing protein 2(gene name synonym)|uniprotkb:Atrophin-1-interacting protein 2(gene name synonym)|uniprotkb:WWP2(gene name)|psi-mi:WWP2(display_short)|uniprotkb:HECT-type E3 ubiquitin transferase WWP2(gene name synonym)	psi-mi:hua1_yeast(display_long)|uniprotkb:HUA1(gene name)|psi-mi:HUA1(display_short)|uniprotkb:YGR268C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11559829|imex:IM-24995-4878	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_008945.2|refseq:NP_001257383.1|refseq:NP_001257384.1|refseq:XP_011521125.1|refseq:XP_011521127.1|refseq:XP_011521128.1|refseq:NP_001257382.1|refseq:NP_955456.1|refseq:XP_016878368.1|refseq:XP_016878369.1|refseq:XP_016878370.1|ensembl:ENSG00000198373(gene)|ensembl:ENST00000359154(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006858"(extracellular transport)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032410"(negative regulation of transporter activity)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0051224"(negative regulation of protein transport)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:1901016"(regulation of potassium ion transmembrane transporter activity)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000569(HECT)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR024928|interpro:IPR035892|interpro:IPR035983|interpro:IPR036020|mint:O00308|rcsb pdb:4Y07|rcsb pdb:5TJ7|rcsb pdb:5TJ8|rcsb pdb:5TJQ|rcsb pdb:6J1Z|rcsb pdb:6RSS|reactome:R-HSA-8948751|reactome:R-HSA-9013406|reactome:R-HSA-9013409|reactome:R-HSA-9013420|reactome:R-HSA-9013507|entrezgene/locuslink:11060(identity)	sgd:S000003500|refseq:NP_011784.3|dip:DIP-1987N|ensemblfungi:YGR268C(gene)|ensemblfungi:YGR268C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|interpro:IPR038910|sgd:YGR268C(identity)	-	-	crc64:78029FD484168793	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Xj0Xssn75HP9sp/tHNe4n83eHPE9606	rogid:xliNG9XUWbYRd0Nbu+xzCgxNrAs559292	intact-crc:C522B9CC6481920E|rigid:YmFWIjYzfPfhf5yuAI2KMCmrd00	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O14641	uniprotkb:P40325	intact:EBI-740850|ensembl:ENSP00000005340|uniprotkb:Q53XM0|uniprotkb:D3DTN3	intact:EBI-23614|uniprotkb:D6VV46|ensemblfungi:YGR268C	psi-mi:dvl2_human(display_long)|uniprotkb:DSH homolog 2(gene name synonym)|uniprotkb:DVL2(gene name)|psi-mi:DVL2(display_short)	psi-mi:hua1_yeast(display_long)|uniprotkb:HUA1(gene name)|psi-mi:HUA1(display_short)|uniprotkb:YGR268C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11559838|imex:IM-24995-4879	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004413.1|ensembl:ENSG00000004975(gene)|ensembl:ENST00000005340(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005109"(frizzled binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0007507"(heart development)|go:"GO:0016235"(aggresome)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044340"(canonical Wnt signaling pathway involved in regulation of cell proliferation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0150012"(positive regulation of neuron projection arborization)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008341(Dishevelled-2 region)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:O14641|rcsb pdb:2REY|rcsb pdb:3CBX|rcsb pdb:3CBY|rcsb pdb:3CBZ|rcsb pdb:3CC0|rcsb pdb:4WIP|rcsb pdb:5LNP|rcsb pdb:5SUY|rcsb pdb:5SUZ|rcsb pdb:6IW3|rcsb pdb:6JCK|reactome:R-HSA-201681|reactome:R-HSA-201688|reactome:R-HSA-2028269|reactome:R-HSA-4086400|reactome:R-HSA-4608870|reactome:R-HSA-4641258|reactome:R-HSA-4641262|reactome:R-HSA-5099900|reactome:R-HSA-5368598|reactome:R-HSA-5663220|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9673324|ensembl:ENSP00000005340|dip:DIP-34433N|entrezgene/locuslink:1856(identity)	sgd:S000003500|refseq:NP_011784.3|dip:DIP-1987N|ensemblfungi:YGR268C(gene)|ensemblfungi:YGR268C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|interpro:IPR038910|sgd:YGR268C(identity)	-	-	crc64:78029FD484168793	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:2Vdc8oRnT4Mz/j+EXQXrL3AszOc9606	rogid:xliNG9XUWbYRd0Nbu+xzCgxNrAs559292	intact-crc:C198D3C1B307A562|rigid:jooQ7Ge+kEOIeZpv8+uU/HTP9Gw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40325	uniprotkb:Q04323	intact:EBI-23614|uniprotkb:D6VV46|ensemblfungi:YGR268C	intact:EBI-1058647|ensembl:ENSP00000303991|uniprotkb:Q9BV93|uniprotkb:Q9BVV5|intact:EBI-1993649	psi-mi:hua1_yeast(display_long)|uniprotkb:HUA1(gene name)|psi-mi:HUA1(display_short)|uniprotkb:YGR268C(locus name)	psi-mi:ubxn1_human(display_long)|uniprotkb:UBXN1(gene name)|psi-mi:UBXN1(display_short)|uniprotkb:SAKS1(gene name synonym)|uniprotkb:SAPK substrate protein 1(gene name synonym)|uniprotkb:UBA/UBX 33.3 kDa protein(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11559856|imex:IM-24995-4881	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003500|refseq:NP_011784.3|dip:DIP-1987N|ensemblfungi:YGR268C(gene)|ensemblfungi:YGR268C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|interpro:IPR038910|sgd:YGR268C(identity)	ensembl:ENSG00000162191(gene)|ensembl:ENST00000301935(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0030425"(dendrite)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0036435"(K48-linked polyubiquitin modification-dependent protein binding)|refseq:NP_001273006.1|refseq:NP_001273007.1|refseq:NP_056937.2|go:"GO:0043025"(neuronal cell body)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0051117"(ATPase binding)|go:"GO:0071796"(K6-linked polyubiquitin modification-dependent protein binding)|go:"GO:1903094"(negative regulation of protein K48-linked deubiquitination)|go:"GO:1904293"(negative regulation of ERAD pathway)|go:"GO:1904855"(proteasome regulatory particle binding)|go:"GO:2000157"(negative regulation of ubiquitin-specific protease activity)|interpro:IPR001012(UBX)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR029071|interpro:IPR041923|reactome:R-HSA-532668|reactome:R-HSA-5693565|go:"GO:0043130"(ubiquitin binding)|refseq:XP_005274090.1|refseq:XP_016873363.1|dip:DIP-29467N|entrezgene/locuslink:51035(identity)	-	crc64:78029FD484168793	crc64:E4E0C8BBAC93F2BB	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:xliNG9XUWbYRd0Nbu+xzCgxNrAs559292	rogid:KdHMRM9FSd6VT6MvJTxzdjARlRw9606	intact-crc:3D321AFB545BBFB1|rigid:Uta6w9dHHb/gnO/HqSVuBGJTaqE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q04323-2	uniprotkb:P40325	intact:EBI-11530712|ensembl:ENSP00000294119	intact:EBI-23614|uniprotkb:D6VV46|ensemblfungi:YGR268C	psi-mi:q04323-2(display_long)|uniprotkb:UBXN1(gene name)|psi-mi:UBXN1(display_short)|uniprotkb:SAKS1(gene name synonym)|uniprotkb:SAPK substrate protein 1(gene name synonym)|uniprotkb:UBA/UBX 33.3 kDa protein(gene name synonym)	psi-mi:hua1_yeast(display_long)|uniprotkb:HUA1(gene name)|psi-mi:HUA1(display_short)|uniprotkb:YGR268C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11559865|imex:IM-24995-4882	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000162191(gene)|ensembl:ENST00000294119(transcript)|intact:EBI-1058647(isoform-parent)|uniprotkb:Q04323-2(isoform-parent)|entrezgene/locuslink:51035(identity)	sgd:S000003500|refseq:NP_011784.3|dip:DIP-1987N|ensemblfungi:YGR268C(gene)|ensemblfungi:YGR268C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|interpro:IPR038910|sgd:YGR268C(identity)	-	isoform-comment:No experimental confirmation available.	crc64:78029FD484168793	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:3DD93eyg5bSqmm3twiOfff+2Bps9606	rogid:xliNG9XUWbYRd0Nbu+xzCgxNrAs559292	intact-crc:B200C307E16AF0E6|rigid:LciiCbDcklBbHVh0PdJE3y0ERzY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O75886	uniprotkb:P40325	intact:EBI-373258|uniprotkb:Q7LDQ0|uniprotkb:Q9UF58|uniprotkb:A8K8A0|uniprotkb:D3DPA1|ensembl:ENSP00000263904	intact:EBI-23614|uniprotkb:D6VV46|ensemblfungi:YGR268C	psi-mi:stam2_human(display_long)|uniprotkb:STAM2(gene name)|psi-mi:STAM2(display_short)|uniprotkb:HBP(gene name synonym)|uniprotkb:Hrs-binding protein(gene name synonym)	psi-mi:hua1_yeast(display_long)|uniprotkb:HUA1(gene name)|psi-mi:HUA1(display_short)|uniprotkb:YGR268C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11559847|imex:IM-24995-4880	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005834.4|ensembl:ENSG00000115145(gene)|ensembl:ENST00000263904(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0015031"(protein transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0031901"(early endosome membrane)|go:"GO:0033565"(ESCRT-0 complex)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR001452(Src homology-3)|interpro:IPR002014(VHS)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR035675|interpro:IPR036028|mint:O75886|rcsb pdb:1X2Q|rcsb pdb:1X5B|rcsb pdb:2L0T|rcsb pdb:5CRV|rcsb pdb:5IXF|reactome:R-HSA-182971|reactome:R-HSA-5689880|reactome:R-HSA-6807004|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8875360|reactome:R-HSA-9013420|reactome:R-HSA-917729|entrezgene/locuslink:10254(identity)	sgd:S000003500|refseq:NP_011784.3|dip:DIP-1987N|ensemblfungi:YGR268C(gene)|ensemblfungi:YGR268C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|interpro:IPR038910|sgd:YGR268C(identity)	-	-	crc64:78029FD484168793	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:e5brcAWS5So29SdnZV3cAm/dZAk9606	rogid:xliNG9XUWbYRd0Nbu+xzCgxNrAs559292	intact-crc:E22054B6E5AA0E49|rigid:0Ll8W5USnqPLfOJFREug13vfCME	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q13137	uniprotkb:P40325	intact:EBI-739580|uniprotkb:B4DDC4|uniprotkb:E7ENK0|uniprotkb:Q53FQ5|uniprotkb:Q53HB5|uniprotkb:Q6IBN9|uniprotkb:Q9BTF7|uniprotkb:B2RBT0|ensembl:ENSP00000258947|uniprotkb:B4E0C0|uniprotkb:E7ETP5|uniprotkb:B4DDT4|uniprotkb:B4DP36|uniprotkb:E9PBE5	intact:EBI-23614|uniprotkb:D6VV46|ensemblfungi:YGR268C	psi-mi:caco2_human(display_long)|uniprotkb:CALCOCO2(gene name)|psi-mi:CALCOCO2(display_short)|uniprotkb:NDP52(gene name synonym)|uniprotkb:Nuclear domain 10 protein NDP52(gene name synonym)|uniprotkb:Antigen nuclear dot 52 kDa protein(gene name synonym)|uniprotkb:Nuclear dot protein 52(gene name synonym)	psi-mi:hua1_yeast(display_long)|uniprotkb:HUA1(gene name)|psi-mi:HUA1(display_short)|uniprotkb:YGR268C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11559874|imex:IM-24995-4883	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001248319.1|refseq:NP_001248320.1|refseq:NP_001248322.1|refseq:NP_005822.1|ensembl:ENSG00000136436(gene)|ensembl:ENST00000258947(transcript)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016032"(viral process)|go:"GO:0016605"(PML body)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0098792"(xenophagy)|go:"GO:1901098"(positive regulation of autophagosome maturation)|interpro:IPR041611|interpro:IPR041641|mint:Q13137|rcsb pdb:2MXP|rcsb pdb:3VVV|rcsb pdb:3VVW|rcsb pdb:4GXL|rcsb pdb:4HAN|rcsb pdb:4XKL|rcsb pdb:5AAQ|rcsb pdb:5Z7A|rcsb pdb:5Z7L|refseq:NP_001248324.1|dip:DIP-57534N|entrezgene/locuslink:10241(identity)	sgd:S000003500|refseq:NP_011784.3|dip:DIP-1987N|ensemblfungi:YGR268C(gene)|ensemblfungi:YGR268C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|interpro:IPR038910|sgd:YGR268C(identity)	-	crc64:609B121DA1A9DCB8	crc64:78029FD484168793	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:N/GPJUGBK+Dh5Cg+csmafphuo9M9606	rogid:xliNG9XUWbYRd0Nbu+xzCgxNrAs559292	intact-crc:68C1F0DB23843FE4|rigid:ZU1zP1fdskcG37I7zNqOy95qCLQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40325	uniprotkb:Q13490	intact:EBI-23614|uniprotkb:D6VV46|ensemblfungi:YGR268C	intact:EBI-514538|uniprotkb:Q16516|uniprotkb:Q4TTG0|uniprotkb:B4E026|ensembl:ENSP00000227758|ensembl:ENSP00000477613	psi-mi:hua1_yeast(display_long)|uniprotkb:HUA1(gene name)|psi-mi:HUA1(display_short)|uniprotkb:YGR268C(locus name)	psi-mi:birc2_human(display_long)|uniprotkb:Inhibitor of apoptosis protein 2(gene name synonym)|uniprotkb:TNFR2-TRAF-signaling complex protein 2(gene name synonym)|uniprotkb:IAP homolog B(gene name synonym)|uniprotkb:RING finger protein 48(gene name synonym)|uniprotkb:BIRC2(gene name)|psi-mi:BIRC2(display_short)|uniprotkb:API1(gene name synonym)|uniprotkb:MIHB(gene name synonym)|uniprotkb:RNF48(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase BIRC2(gene name synonym)|uniprotkb:Cellular inhibitor of apoptosis 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11559884|imex:IM-24995-4884	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003500|refseq:NP_011784.3|dip:DIP-1987N|ensemblfungi:YGR268C(gene)|ensemblfungi:YGR268C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|interpro:IPR038910|sgd:YGR268C(identity)	refseq:NP_001157.1|refseq:NP_001243095.1|refseq:NP_001243092.1|dip:DIP-33485N|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0045471"(response to ethanol)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051087"(chaperone binding)|go:"GO:0051591"(response to cAMP)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060544"(regulation of necroptotic process)|go:"GO:0060546"(negative regulation of necroptotic process)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070266"(necroptotic process)|go:"GO:0070424"(regulation of nucleotide-binding oligomerization domain containing signaling pathway)|go:"GO:0098770"(FBXO family protein binding)|go:"GO:1901222"(regulation of NIK/NF-kappaB signaling)|go:"GO:1902443"(negative regulation of ripoptosome assembly involved in necroptotic process)|go:"GO:1902523"(positive regulation of protein K63-linked ubiquitination)|go:"GO:1902524"(positive regulation of protein K48-linked ubiquitination)|go:"GO:1902527"(positive regulation of protein monoubiquitination)|go:"GO:2000116"(regulation of cysteine-type endopeptidase activity)|go:"GO:2000377"(regulation of reactive oxygen species metabolic process)|interpro:IPR001315(Caspase Recruitment)|interpro:IPR001370(Proteinase inhibitor I32, inhibitor of apoptosis)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011029(DEATH-like)|interpro:IPR041933|mint:Q13490|rcsb pdb:1QBH|rcsb pdb:2L9M|rcsb pdb:3D9T|rcsb pdb:3D9U|rcsb pdb:3M1D|rcsb pdb:3MUP|rcsb pdb:3OZ1|rcsb pdb:3T6P|rcsb pdb:3UW4|rcsb pdb:4EB9|rcsb pdb:4HY4|rcsb pdb:4HY5|rcsb pdb:4KMN|rcsb pdb:4LGE|rcsb pdb:4LGU|rcsb pdb:4MTI|rcsb pdb:4MU7|rcsb pdb:5M6N|rcsb pdb:6EXW|rcsb pdb:6HPR|rcsb pdb:6W74|rcsb pdb:6W7O|rcsb pdb:6W8I|reactome:R-HSA-111465|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-5213460|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5668541|reactome:R-HSA-5675482|reactome:R-HSA-5676594|reactome:R-HSA-5689880|reactome:R-HSA-937041|ensembl:ENSG00000110330(gene)|ensembl:ENST00000227758(transcript)|ensembl:ENST00000613397(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001741"(XY body)|go:"GO:0001890"(placenta development)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0016740"(transferase activity)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034121"(regulation of toll-like receptor signaling pathway)|go:"GO:0035631"(CD40 receptor complex)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0039535"(regulation of RIG-I signaling pathway)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|entrezgene/locuslink:329(identity)	-	crc64:78029FD484168793	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:xliNG9XUWbYRd0Nbu+xzCgxNrAs559292	rogid:FOikzyDyDtlv2l69i/WNDNq674A9606	intact-crc:FD4C01A3AC5CF9FB|rigid:Pl0sRkozh4Fe0A0tmTVh9BsVWgY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40325	uniprotkb:Q15025	intact:EBI-23614|uniprotkb:D6VV46|ensemblfungi:YGR268C	intact:EBI-357849|uniprotkb:A4F1W8|uniprotkb:O76008|uniprotkb:Q96EL9|uniprotkb:Q99833|uniprotkb:Q9H1J3|uniprotkb:B7Z699|uniprotkb:Q6N077|ensembl:ENSP00000317891|ensembl:ENSP00000428187|ensembl:ENSP00000430760|uniprotkb:A4F1W9|uniprotkb:A4F1X2|uniprotkb:A4F1X4|uniprotkb:A4F1X5|uniprotkb:A4F1X6|uniprotkb:A4F1X7|uniprotkb:A4F1X9|uniprotkb:E7EPY1|uniprotkb:E7ET96|uniprotkb:Q05KP3|uniprotkb:Q05KP4	psi-mi:hua1_yeast(display_long)|uniprotkb:HUA1(gene name)|psi-mi:HUA1(display_short)|uniprotkb:YGR268C(locus name)	psi-mi:tnip1_human(display_long)|uniprotkb:TNIP1(gene name)|psi-mi:TNIP1(display_short)|uniprotkb:KIAA0113(gene name synonym)|uniprotkb:NAF1(gene name synonym)|uniprotkb:Nef-associated factor 1(gene name synonym)|uniprotkb:HIV-1 Nef-interacting protein(gene name synonym)|uniprotkb:Virion-associated nuclear shuttling protein(gene name synonym)|uniprotkb:Nip40-1(gene name synonym)|uniprotkb:A20-binding inhibitor of NF-kappa-B activation 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11559893|imex:IM-24995-4885	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003500|refseq:NP_011784.3|dip:DIP-1987N|ensemblfungi:YGR268C(gene)|ensemblfungi:YGR268C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|interpro:IPR038910|sgd:YGR268C(identity)	refseq:NP_006049.3|refseq:NP_001239319.1|refseq:NP_001239320.1|refseq:NP_001239321.1|refseq:NP_001239322.1|refseq:NP_001245383.1|dip:DIP-27577N|refseq:NP_001239315.1|ensembl:ENSG00000145901(gene)|ensembl:ENST00000315050(transcript)|ensembl:ENST00000521591(transcript)|ensembl:ENST00000522226(transcript)|go:"GO:0002755"(MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0006952"(defense response)|go:"GO:0006954"(inflammatory response)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0009101"(glycoprotein biosynthetic process)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0085032"(modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade)|go:"GO:1903003"(positive regulation of protein deubiquitination)|interpro:IPR033372|mint:Q15025|reactome:R-HSA-5689896|go:"GO:0051019"(mitogen-activated protein kinase binding)|refseq:NP_001239314.1|refseq:NP_001245384.1|refseq:NP_001245385.1|refseq:XP_006714814.1|refseq:XP_006714815.1|entrezgene/locuslink:10318(identity)	-	crc64:78029FD484168793	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:xliNG9XUWbYRd0Nbu+xzCgxNrAs559292	rogid:16Vjb5CuGTAbW2M22qbCxgXtV1o9606	intact-crc:C35CAD18FDF45006|rigid:yPFZ0WNJj6iZqkuwZFycMhRekpE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96C32	uniprotkb:P40325	intact:EBI-745483|ensembl:ENSP00000443053	intact:EBI-23614|uniprotkb:D6VV46|ensemblfungi:YGR268C	psi-mi:q96c32_human(display_long)|uniprotkb:UBC(gene name)|psi-mi:UBC(display_short)	psi-mi:hua1_yeast(display_long)|uniprotkb:HUA1(gene name)|psi-mi:HUA1(display_short)|uniprotkb:YGR268C(locus name)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11559903|imex:IM-24995-4886	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000150991(gene)|ensembl:ENST00000538617(transcript)|interpro:IPR000626(Ubiquitin)|interpro:IPR019954|interpro:IPR019956|interpro:IPR029071|entrezgene/locuslink:7316(identity)	sgd:S000003500|refseq:NP_011784.3|dip:DIP-1987N|ensemblfungi:YGR268C(gene)|ensemblfungi:YGR268C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|interpro:IPR038910|sgd:YGR268C(identity)	-	-	crc64:78029FD484168793	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:IkHD1AAO/mSSvaZqrZi5tXVfPOw9606	rogid:xliNG9XUWbYRd0Nbu+xzCgxNrAs559292	intact-crc:DDE5C855E4AFF3C1|rigid:yFAItV8WCJx6w3KzRXcFvymZeww	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40325	uniprotkb:Q96CV9-2	intact:EBI-23614|uniprotkb:D6VV46|ensemblfungi:YGR268C	intact:EBI-9091423|ensembl:ENSP00000368027|ensembl:ENSP00000368040	psi-mi:hua1_yeast(display_long)|uniprotkb:HUA1(gene name)|psi-mi:HUA1(display_short)|uniprotkb:YGR268C(locus name)	psi-mi:q96cv9-2(display_long)|uniprotkb:E3-14.7K-interacting protein(gene name synonym)|uniprotkb:FIP-2(gene name synonym)|uniprotkb:FIP2(gene name synonym)|uniprotkb:GLC1E(gene name synonym)|uniprotkb:HIP7(gene name synonym)|uniprotkb:HYPL(gene name synonym)|uniprotkb:Huntingtin yeast partner L(gene name synonym)|uniprotkb:Huntingtin-interacting protein 7(gene name synonym)|uniprotkb:Huntingtin-interacting protein L(gene name synonym)|uniprotkb:NEMO-related protein(gene name synonym)|uniprotkb:NRP(gene name synonym)|uniprotkb:Optic neuropathy-inducing protein(gene name synonym)|uniprotkb:Transcription factor IIIA-interacting protein(gene name synonym)|uniprotkb:OPTN(gene name)|psi-mi:OPTN(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11559921|imex:IM-24995-4888	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003500|refseq:NP_011784.3|dip:DIP-1987N|ensemblfungi:YGR268C(gene)|ensemblfungi:YGR268C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|interpro:IPR038910|sgd:YGR268C(identity)	intact:EBI-748974(isoform-parent)|ensembl:ENST00000378752(transcript)|ensembl:ENST00000378764(transcript)|ensembl:ENSG00000123240(gene)|uniprotkb:Q96CV9-2(isoform-parent)|entrezgene/locuslink:10133(identity)	-	crc64:78029FD484168793	isoform-comment:No experimental confirmation available.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2018/04/06	rogid:xliNG9XUWbYRd0Nbu+xzCgxNrAs559292	rogid:ygzEQkiDJwDAMUuFQuOWsSIqwAk9606	intact-crc:E16F62559821E8A8|rigid:uOCMr9eJT/Mm90dBbTyVfrbsS5o	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40325	uniprotkb:Q96CV9	intact:EBI-23614|uniprotkb:D6VV46|ensemblfungi:YGR268C	intact:EBI-748974|uniprotkb:Q5T672|uniprotkb:Q5T673|uniprotkb:Q5T674|uniprotkb:Q5T675|uniprotkb:Q7LDL9|uniprotkb:Q8N562|uniprotkb:Q9UET9|uniprotkb:Q9UEV4|uniprotkb:Q9Y218|uniprotkb:B3KP00|uniprotkb:D3DRS4|uniprotkb:D3DRS8|ensembl:ENSP00000263036|ensembl:ENSP00000368021|ensembl:ENSP00000368022|ensembl:ENSP00000368032	psi-mi:hua1_yeast(display_long)|uniprotkb:HUA1(gene name)|psi-mi:HUA1(display_short)|uniprotkb:YGR268C(locus name)	psi-mi:optn_human(display_long)|uniprotkb:HYPL(gene name synonym)|uniprotkb:Optic neuropathy-inducing protein(gene name synonym)|uniprotkb:E3-14.7K-interacting protein(gene name synonym)|uniprotkb:FIP-2(gene name synonym)|uniprotkb:Huntingtin-interacting protein L(gene name synonym)|uniprotkb:Huntingtin yeast partner L(gene name synonym)|uniprotkb:NEMO-related protein(gene name synonym)|uniprotkb:Transcription factor IIIA-interacting protein(gene name synonym)|uniprotkb:OPTN(gene name)|psi-mi:OPTN(display_short)|uniprotkb:FIP2(gene name synonym)|uniprotkb:GLC1E(gene name synonym)|uniprotkb:NRP(gene name synonym)|uniprotkb:HIP7(gene name synonym)|uniprotkb:Huntingtin-interacting protein 7(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11559912|imex:IM-24995-4887	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003500|refseq:NP_011784.3|dip:DIP-1987N|ensemblfungi:YGR268C(gene)|ensemblfungi:YGR268C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|interpro:IPR038910|sgd:YGR268C(identity)	refseq:NP_001008212.1|refseq:NP_001008213.1|refseq:NP_001008214.1|refseq:NP_068815.2|ensembl:ENSG00000123240(gene)|ensembl:ENST00000263036(transcript)|ensembl:ENST00000378747(transcript)|ensembl:ENST00000378748(transcript)|ensembl:ENST00000378757(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001920"(negative regulation of receptor recycling)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0007030"(Golgi organization)|go:"GO:0007165"(signal transduction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008219"(cell death)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0061734"(parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:1904417"(positive regulation of xenophagy)|interpro:IPR021063|interpro:IPR032419|interpro:IPR032939|interpro:IPR034735|mint:Q96CV9|rcsb pdb:2LO4|rcsb pdb:2LUE|rcsb pdb:3VTV|rcsb pdb:3VTW|rcsb pdb:5AAZ|rcsb pdb:5B83|rcsb pdb:5EOA|rcsb pdb:5EOF|rcsb pdb:7CZM|reactome:R-HSA-2565942|reactome:R-HSA-8854214|dip:DIP-42001N|entrezgene/locuslink:10133(identity)	-	crc64:78029FD484168793	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2018/04/06	rogid:xliNG9XUWbYRd0Nbu+xzCgxNrAs559292	rogid:jcCTXDx1bJq3K5mgNUD73jeWeBU9606	intact-crc:5789874A0060A9E2|rigid:XRF29S3IqlMdBF01fxwAe3LRwug	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40325	uniprotkb:Q9NPJ6	intact:EBI-23614|uniprotkb:D6VV46|ensemblfungi:YGR268C	intact:EBI-394607|uniprotkb:Q9BS95|uniprotkb:Q9NYR5|uniprotkb:Q53GB4|uniprotkb:Q53H68|uniprotkb:Q5T912|uniprotkb:Q6FHC4|uniprotkb:Q6IA79|uniprotkb:B4DX67|ensembl:ENSP00000258648	psi-mi:hua1_yeast(display_long)|uniprotkb:HUA1(gene name)|psi-mi:HUA1(display_short)|uniprotkb:YGR268C(locus name)	psi-mi:med4_human(display_long)|uniprotkb:HSPC126(orf name)|uniprotkb:DRIP36(gene name synonym)|uniprotkb:MED4(gene name)|psi-mi:MED4(display_short)|uniprotkb:ARC36(gene name synonym)|uniprotkb:Mediator complex subunit 4(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex 36 kDa component(gene name synonym)|uniprotkb:Activator-recruited cofactor 36 kDa component(gene name synonym)|uniprotkb:TRAP/SMCC/PC2 subunit p36 subunit(gene name synonym)|uniprotkb:VDRIP(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11559930|imex:IM-24995-4889	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003500|refseq:NP_011784.3|dip:DIP-1987N|ensemblfungi:YGR268C(gene)|ensemblfungi:YGR268C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|interpro:IPR038910|sgd:YGR268C(identity)	refseq:NP_001257558.1|refseq:NP_054885.1|ensembl:ENSG00000136146(gene)|ensembl:ENST00000258648(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0070847"(core mediator complex)|interpro:IPR019258|mint:Q9NPJ6|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|entrezgene/locuslink:29079(identity)	-	crc64:78029FD484168793	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:xliNG9XUWbYRd0Nbu+xzCgxNrAs559292	rogid:Bept2Oec50gruA9e4pf+eEUiANM9606	intact-crc:48848DFCDEEEADB4|rigid:YjjL0fdYfJwMYhA7NMox2pVSZCI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40348	uniprotkb:Q8NHQ1	intact:EBI-14992|uniprotkb:E9P8U1|uniprotkb:D6VWN9|ensemblfungi:YJR068W	intact:EBI-739624|ensembl:ENSP00000264982|ensembl:ENSP00000419231|uniprotkb:Q96B31|uniprotkb:Q9H2C3|uniprotkb:Q9H2Z1|uniprotkb:Q9H940|uniprotkb:D3DNE9|uniprotkb:B7Z5I8|uniprotkb:B7Z7E8|uniprotkb:F5GZX8	psi-mi:rfc2_yeast(display_long)|uniprotkb:RFC2(gene name)|psi-mi:RFC2(display_short)|uniprotkb:YJR068W(locus name)|uniprotkb:J1808(orf name)|uniprotkb:Activator 1 41 kDa subunit(gene name synonym)	psi-mi:cep70_human(display_long)|uniprotkb:CEP70(gene name)|psi-mi:CEP70(display_short)|uniprotkb:BITE(gene name synonym)|uniprotkb:p10-binding protein(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11559948|imex:IM-24995-4891	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003829|refseq:NP_012602.3|ensemblfungi:YJR068W(gene)|ensemblfungi:YJR068W_mRNA(transcript)|go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005663"(DNA replication factor C complex)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006272"(leading strand elongation)|go:"GO:0006281"(DNA repair)|go:"GO:0006298"(mismatch repair)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0031389"(Rad17 RFC-like complex)|go:"GO:0031390"(Ctf18 RFC-like complex)|go:"GO:0031391"(Elg1 RFC-like complex)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR013748(Replication factor C)|interpro:IPR027417|rcsb pdb:1SXJ|reactome:R-SCE-110312|reactome:R-SCE-110320|reactome:R-SCE-176187|reactome:R-SCE-5655862|reactome:R-SCE-5656121|reactome:R-SCE-5656169|reactome:R-SCE-5696397|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-69091|dip:DIP-2528N|mint:P40348|sgd:YJR068W(identity)	ensembl:ENSG00000114107(gene)|ensembl:ENST00000264982(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|interpro:IPR019734|interpro:IPR037692|mint:Q8NHQ1|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|ensembl:ENST00000484888(transcript)|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_077817.2|refseq:XP_016862764.1|refseq:NP_001275893.1|refseq:NP_001275894.1|refseq:NP_001275895.1|refseq:NP_001275896.1|refseq:NP_001307527.1|refseq:NP_001307529.1|entrezgene/locuslink:80321(identity)	-	crc64:59B2C4223B0D13BF	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Z0Rwf5Gg3mAcfGIC8toCXrjnD2g559292	rogid:S4yveQWcvdVtAUX65gqrJ5Dv0Mc9606	intact-crc:6589FCE1F6987449|rigid:ZQXGmLKGNXI8B5Paj1yQo5BBS6A	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40325	uniprotkb:Q9UMX0	intact:EBI-23614|uniprotkb:D6VV46|ensemblfungi:YGR268C	intact:EBI-741480|uniprotkb:Q8IXS9|uniprotkb:Q8N2Q3|uniprotkb:Q9H0T8|uniprotkb:Q9H3R4|uniprotkb:Q9HAZ5|intact:EBI-28967608|ensembl:ENSP00000365576|uniprotkb:Q5T6J5|uniprotkb:Q5T6J9|uniprotkb:A0A024R284	psi-mi:hua1_yeast(display_long)|uniprotkb:HUA1(gene name)|psi-mi:HUA1(display_short)|uniprotkb:YGR268C(locus name)	psi-mi:ubql1_human(display_long)|uniprotkb:Protein linking IAP with cytoskeleton 1(gene name synonym)|uniprotkb:UBQLN1(gene name)|psi-mi:UBQLN1(display_short)|uniprotkb:DA41(gene name synonym)|uniprotkb:PLIC1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11559939|imex:IM-24995-4890	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003500|refseq:NP_011784.3|dip:DIP-1987N|ensemblfungi:YGR268C(gene)|ensemblfungi:YGR268C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|interpro:IPR038910|sgd:YGR268C(identity)	ensembl:ENST00000257468|ensembl:ENSP00000257468|ensembl:ENSP00000365576|ensembl:ENSG00000135018(gene)|ensembl:ENST00000376395(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000502"(proteasome complex)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016235"(aggresome)|go:"GO:0016236"(macroautophagy)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0019900"(kinase binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035973"(aggrephagy)|go:"GO:0042802"(identical protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0097352"(autophagosome maturation)|go:"GO:1901340"(negative regulation of store-operated calcium channel activity)|go:"GO:1902175"(regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)|interpro:IPR000626(Ubiquitin)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR028430|interpro:IPR029071|mint:Q9UMX0|rcsb pdb:2JY5|rcsb pdb:2JY6|rcsb pdb:2KLC|reactome:R-HSA-8856825|refseq:NP_038466.2|refseq:NP_444295.1|dip:DIP-41629N|entrezgene/locuslink:29979(identity)	-	crc64:78029FD484168793	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:xliNG9XUWbYRd0Nbu+xzCgxNrAs559292	rogid:nCFfZbGCTvRYaXhQ4R99XblslvM9606	intact-crc:91EA92468D6AD5C0|rigid:MJOj4t/4plp19fbfmUPOCxunltg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:A2A369	uniprotkb:P40354	intact:EBI-11530808|ensembl:ENSP00000371766	intact:EBI-12280|ensemblfungi:YJR062C|uniprotkb:D6VWN3	psi-mi:a2a369_human(display_long)|uniprotkb:DOCK8(gene name)|psi-mi:DOCK8(display_short)	psi-mi:nta1_yeast(display_long)|uniprotkb:J1742(orf name)|uniprotkb:YJR062C(locus name)|uniprotkb:NTA1(gene name)|psi-mi:NTA1(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11559957|imex:IM-24995-4892	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000107099(gene)|ensembl:ENST00000382329(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0007264"(small GTPase mediated signal transduction)|interpro:IPR010703(Dedicator of cytokinesis)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026791|interpro:IPR027007|interpro:IPR027357|interpro:IPR035892|interpro:IPR043161|interpro:IPR043162|entrezgene/locuslink:81704(identity)	ensemblfungi:YJR062C(gene)|ensemblfungi:YJR062C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0008418"(protein-N-terminal asparagine amidohydrolase activity)|go:"GO:0030163"(protein catabolic process)|go:"GO:0031365"(N-terminal protein amino acid modification)|go:"GO:0070773"(protein-N-terminal glutamine amidohydrolase activity)|interpro:IPR003010(Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase)|interpro:IPR036526|interpro:IPR039703|refseq:NP_012596.3|sgd:S000003823|dip:DIP-6478N|sgd:YJR062C(identity)	-	-	crc64:E6259FBBFB25A889	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Sa5ulmmVxrpxZ+GAhN64RAHXYdk9606	rogid:WuneoUOKjrppTwFurxcO41hR/W0559292	intact-crc:2A0BF47555F9ACB6|rigid:hW09oO4w8ZshylXet9c+t1cQ05Q	false	sufficient binding region:1054-1566	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P37198	uniprotkb:P40368	intact:EBI-347978|intact:EBI-28983799|ensembl:ENSP00000305503|ensembl:ENSP00000407331|ensembl:ENSP00000471191|ensembl:ENSP00000473192|uniprotkb:Q6GTM2|uniprotkb:Q503A4|uniprotkb:Q96C43|uniprotkb:Q9NSL1|uniprotkb:B3KWU5	intact:EBI-12331|ensemblfungi:YJL061W|uniprotkb:D6VWC1	psi-mi:nup62_human(display_long)|uniprotkb:NUP62(gene name)|psi-mi:NUP62(display_short)|uniprotkb:62 kDa nucleoporin(gene name synonym)|uniprotkb:Nucleoporin Nup62(gene name synonym)	psi-mi:nup82_yeast(display_long)|uniprotkb:NUP82(gene name)|psi-mi:NUP82(display_short)|uniprotkb:YJL061W(locus name)|uniprotkb:J1135(orf name)|uniprotkb:HRB187(orf name)|uniprotkb:Nuclear pore protein NUP82(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11559968|imex:IM-24995-4893	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_714941.1|ensembl:ENSG00000213024(gene)|ensembl:ENST00000352066(transcript)|ensembl:ENST00000422090(transcript)|ensembl:ENST00000596217(transcript)|ensembl:ENST00000597029(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005642"(annulate lamellae)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007100"(mitotic centrosome separation)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007569"(cell aging)|go:"GO:0008219"(cell death)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0003682"(chromatin binding)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0019894"(kinesin binding)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042306"(regulation of protein import into nucleus)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043069"(negative regulation of programmed cell death)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045742"(positive regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046578"(regulation of Ras protein signal transduction)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0046601"(positive regulation of centriole replication)|go:"GO:0051028"(mRNA transport)|go:"GO:0051425"(PTB domain binding)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0072686"(mitotic spindle)|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|go:"GO:0090543"(Flemming body)|go:"GO:0098534"(centriole assembly)|go:"GO:1903438"(positive regulation of mitotic cytokinetic process)|go:"GO:1904781"(positive regulation of protein localization to centrosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR007758(Nucleoporin, Nsp1-like, C-terminal)|interpro:IPR026010|interpro:IPR033072|mint:P37198|rcsb pdb:2H4D|rcsb pdb:5IJN|rcsb pdb:5IJO|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|refseq:NP_714940.1|refseq:NP_001180286.1|refseq:NP_036478.2|refseq:NP_057637.2|ensembl:ENSP00000305503|ensembl:ENSP00000407331|ensembl:ENSP00000471191|ensembl:ENSP00000473192|dip:DIP-29749N|entrezgene/locuslink:23636(identity)	refseq:NP_012474.1|sgd:S000003597|ensemblfungi:YJL061W(gene)|ensemblfungi:YJL061W_mRNA(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0005634"(nucleus)|interpro:IPR037700|rcsb pdb:3PBP|rcsb pdb:3TKN|go:"GO:0005643"(nuclear pore)|go:"GO:0005829"(cytosol)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0044612"(nuclear pore linkers)|go:"GO:0044614"(nuclear pore cytoplasmic filaments)|mint:P40368|dip:DIP-913N|sgd:YJL061W(identity)	-	-	crc64:C379B5E111E26B50	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:v7mvKvTtVEnLMwcpUZIcdAzge009606	rogid:g1+jqOMmde8phrNI9H7nFlXwjH0559292	intact-crc:6AE338B6B01D75A6|rigid:RwOsFdGv+DFarKE9DT5kv5U33iw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9Y294	uniprotkb:P02309	intact:EBI-749553|uniprotkb:Q6IA08|uniprotkb:Q9P014|ensembl:ENSP00000229595	intact:EBI-8113|uniprotkb:D6VQ10|ensemblfungi:YBR009C|ensemblfungi:YNL030W	psi-mi:asf1a_human(display_long)|uniprotkb:Anti-silencing function protein 1 homolog A(gene name synonym)|uniprotkb:CCG1-interacting factor A(gene name synonym)|uniprotkb:ASF1A(gene name)|psi-mi:ASF1A(display_short)|uniprotkb:CGI-98(orf name)|uniprotkb:HSPC146(orf name)	psi-mi:h4_yeast(display_long)|uniprotkb:N2752(orf name)|uniprotkb:YBR0122(orf name)|uniprotkb:YBR009C(locus name)|uniprotkb:YNL030W(locus name)|uniprotkb:HHF1(gene name)|psi-mi:HHF1(display_short)|uniprotkb:HHF2(gene name)|psi-mi:HHF2(display_short)	psi-mi:"MI:0397"(two hybrid array)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11559989|imex:IM-24995-4895	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_054753.1|dip:DIP-29241N|ensembl:ENSG00000111875(gene)|ensembl:ENST00000229595(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0042692"(muscle cell differentiation)|interpro:IPR006818(Anti-silencing protein, ASF1-like)|interpro:IPR036747|mint:Q9Y294|rcsb pdb:1TEY|rcsb pdb:2I32|rcsb pdb:2IIJ|rcsb pdb:2IO5|rcsb pdb:3AAD|rcsb pdb:5C3I|rcsb pdb:6F0G|rcsb pdb:6F0H|rcsb pdb:6ZUF|reactome:R-HSA-2559584|rcsb pdb:6F0F|entrezgene/locuslink:25842(identity)	refseq:NP_009563.1|refseq:NP_014368.1|sgd:S000000213|sgd:S000004975|dip:DIP-418N|mint:P02309|ensemblfungi:YBR009C(gene)|ensemblfungi:YBR009C_mRNA(transcript)|ensemblfungi:YNL030W(gene)|ensemblfungi:YNL030W_mRNA(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0006333"(chromatin assembly or disassembly)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0034729"(histone H3-K79 methylation)|go:"GO:0043935"(sexual sporulation resulting in formation of a cellular spore)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0061587"(transfer RNA gene-mediated silencing)|interpro:IPR001951(Histone H4)|interpro:IPR009072(Histone-fold)|interpro:IPR019809|interpro:IPR035425|rcsb pdb:1E6I|rcsb pdb:1ID3|rcsb pdb:1Q1A|rcsb pdb:1SZC|rcsb pdb:1SZD|rcsb pdb:2DVQ|rcsb pdb:2DVR|rcsb pdb:2E3K|rcsb pdb:2FSB|rcsb pdb:2H2H|rcsb pdb:2L5A|rcsb pdb:2QQF|rcsb pdb:2QQG|rcsb pdb:3TO6|rcsb pdb:4JJN|rcsb pdb:4KUD|rcsb pdb:4PSX|rcsb pdb:4TWI|rcsb pdb:4TWJ|rcsb pdb:5W0V|rcsb pdb:5ZBA|rcsb pdb:5ZBB|rcsb pdb:6GEJ|rcsb pdb:6GEN|rcsb pdb:6QLD|rcsb pdb:6RXJ|rcsb pdb:6RXK|rcsb pdb:6RXL|rcsb pdb:6RXM|rcsb pdb:6RXO|rcsb pdb:6RXP|rcsb pdb:6RXQ|rcsb pdb:6RXR|rcsb pdb:7K78|rcsb pdb:7K7G|reactome:R-SCE-2299718|reactome:R-SCE-2559580|reactome:R-SCE-3214842|reactome:R-SCE-3214847|reactome:R-SCE-3214858|reactome:R-SCE-4551638|reactome:R-SCE-9018519|sgd:YBR009C(identity)|sgd:YNL030W(identity)	-	caution:This sequence has been withdrawn from Uniprot.	crc64:69B7D1F89E62DE41	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:rIMptRSOYD+wfp0dMEHjhNNsHXQ9606	rogid:wGtUrumyxGKsW9BEzkBW3FwvwUo559292	rigid:CcW8ft9xR+nvB26MswK/6i200ZQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O95751	uniprotkb:P43592	intact:EBI-740738|ensembl:ENSP00000359557|uniprotkb:Q6IAR6	intact:EBI-22932|uniprotkb:D6VTN8|ensemblfungi:YFR008W	psi-mi:ldoc1_human(display_long)|uniprotkb:Leucine zipper protein down-regulated in cancer cells(gene name synonym)|uniprotkb:LDOC1(gene name)|psi-mi:LDOC1(display_short)|uniprotkb:BCUR1(gene name synonym)	psi-mi:far7_yeast(display_long)|uniprotkb:YFR008W(locus name)|uniprotkb:FAR7(gene name)|psi-mi:FAR7(display_short)	psi-mi:"MI:0729"(luminescence based mammalian interactome mapping)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11548215|imex:IM-24995-2732	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_036449.1|ensembl:ENSG00000182195(gene)|ensembl:ENST00000370526(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071225"(cellular response to muramyl dipeptide)|interpro:IPR032549|interpro:IPR032567|entrezgene/locuslink:23641(identity)	sgd:S000001904|refseq:NP_116663.1|dip:DIP-1315N|mint:P43592|ensemblfungi:YFR008W(gene)|ensemblfungi:YFR008W_mRNA(transcript)|go:"GO:0000321"(re-entry into mitotic cell cycle after pheromone arrest)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|sgd:YFR008W(identity)	-	-	crc64:81156978FF7AAD54	figure legend:Table EV7|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2015/12/14	2016/02/09	rogid:Ediu0oNiZ/+YVY8l3fNdgP5A+v09606	rogid:RB7IaPAzOtEtryalHHz8psxOYqw559292	intact-crc:4378A945E2F0F68C|rigid:O7PdVOCZde1KYP3b4BIZbVVrlrE	false	tandem tag:n-n	renilla luciferase protein tag:n-n	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P35719	uniprotkb:O95273	intact:EBI-16255|ensemblfungi:YKL142W|uniprotkb:D6VX54	intact:EBI-748961|uniprotkb:A8K3Q0|uniprotkb:A8K3U2|uniprotkb:Q6ZQN9|uniprotkb:Q7Z519|uniprotkb:Q8NBS7|uniprotkb:Q8NBY2|uniprotkb:Q9NS19|uniprotkb:Q9NYH3|uniprotkb:Q9UHX9|ensembl:ENSP00000300213	psi-mi:mrp8_yeast(display_long)|uniprotkb:MRP8(gene name)|psi-mi:MRP8(display_short)|uniprotkb:YKL3(orf name)|uniprotkb:YKL142W(locus name)	psi-mi:ccdb1_human(display_long)|uniprotkb:Grap2 and cyclin-D-interacting protein(gene name synonym)|uniprotkb:Human homolog of Maid(gene name synonym)|uniprotkb:CCNDBP1(gene name)|psi-mi:CCNDBP1(display_short)|uniprotkb:DIP1(gene name synonym)|uniprotkb:GCIP(gene name synonym)|uniprotkb:HHM(gene name synonym)	psi-mi:"MI:0729"(luminescence based mammalian interactome mapping)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11548202|imex:IM-24995-2731	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012780.1|sgd:S000001625|ensemblfungi:YKL142W(gene)|go:"GO:0005737"(cytoplasm)|interpro:IPR012917(Ribosomal protein MRP8, mitochondrial)|ensemblfungi:YKL142W_mRNA(transcript)|dip:DIP-1437N|mint:P35719|sgd:YKL142W(identity)	refseq:NP_036274.3|ensembl:ENSG00000166946(gene)|ensembl:ENST00000300213(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0016604"(nuclear body)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR026907|mint:O95273|rcsb pdb:3AY5|entrezgene/locuslink:23582(identity)	-	crc64:CCAD54B7581A5ABE	-	figure legend:Table EV7|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2015/12/14	2016/02/09	rogid:xrv86SZgOYjf+CaLkNdme45DC9s559292	rogid:Vi9aoFc+Mov6P3X6KGmsTxXqxvM9606	intact-crc:9ECC99CEACDACF6C|rigid:4erpV7VkNjR/NOhLjNIqNdj0S1g	false	renilla luciferase protein tag:n-n	tandem tag:n-n	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P00431	uniprotkb:P43355	intact:EBI-4389|uniprotkb:Q6Q5M9|uniprotkb:D6VXC7|ensemblfungi:YKR066C	intact:EBI-740978|ensembl:ENSP00000349085|uniprotkb:O00346|uniprotkb:B2RC81	psi-mi:ccpr_yeast(display_long)|uniprotkb:CCP1(gene name)|psi-mi:CCP1(display_short)|uniprotkb:CCP(gene name synonym)|uniprotkb:CPO(gene name synonym)|uniprotkb:YKR066C(locus name)	psi-mi:maga1_human(display_long)|uniprotkb:MAGE-1 antigen(gene name synonym)|uniprotkb:Antigen MZ2-E(gene name synonym)|uniprotkb:Cancer/testis antigen 1.1(gene name synonym)|uniprotkb:MAGEA1(gene name)|psi-mi:MAGEA1(display_short)|uniprotkb:MAGE1(gene name synonym)|uniprotkb:MAGE1A(gene name synonym)	psi-mi:"MI:0729"(luminescence based mammalian interactome mapping)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11548241|imex:IM-24995-2734	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012992.1|sgd:S000001774|dip:DIP-6251N|ensemblfungi:YKR066C(gene)|ensemblfungi:YKR066C_mRNA(transcript)|go:"GO:0000302"(response to reactive oxygen species)|go:"GO:0004130"(cytochrome-c peroxidase activity)|go:"GO:0004601"(peroxidase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0020037"(heme binding)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0046872"(metal ion binding)|interpro:IPR002016(Haem peroxidase, plant/fungal/bacterial)|interpro:IPR002207(Plant ascorbate peroxidase)|interpro:IPR010255(Haem peroxidase)|interpro:IPR019793|interpro:IPR019794|interpro:IPR044831|rcsb pdb:1A2F|rcsb pdb:1A2G|rcsb pdb:1AA4|rcsb pdb:1AC4|rcsb pdb:1AC8|rcsb pdb:1AEB|rcsb pdb:1AED|rcsb pdb:1AEE|rcsb pdb:1AEF|rcsb pdb:1AEG|rcsb pdb:1AEH|rcsb pdb:1AEJ|rcsb pdb:1AEK|rcsb pdb:1AEM|rcsb pdb:1AEN|rcsb pdb:1AEO|rcsb pdb:1AEQ|rcsb pdb:1AES|rcsb pdb:1AET|rcsb pdb:1AEU|rcsb pdb:1AEV|rcsb pdb:1BEJ|rcsb pdb:1BEK|rcsb pdb:1BEM|rcsb pdb:1BEP|rcsb pdb:1BEQ|rcsb pdb:1BES|rcsb pdb:1BJ9|rcsb pdb:1BVA|rcsb pdb:1CCA|rcsb pdb:1CCB|rcsb pdb:1CCC|rcsb pdb:1CCE|rcsb pdb:1CCG|rcsb pdb:1CCI|rcsb pdb:1CCJ|rcsb pdb:1CCK|rcsb pdb:1CCL|rcsb pdb:1CCP|rcsb pdb:1CMP|rcsb pdb:1CMQ|rcsb pdb:1CMT|rcsb pdb:1CPD|rcsb pdb:1CPE|rcsb pdb:1CPF|rcsb pdb:1CPG|rcsb pdb:1CYF|rcsb pdb:1DCC|rcsb pdb:1DJ1|rcsb pdb:1DJ5|rcsb pdb:1DS4|rcsb pdb:1DSE|rcsb pdb:1DSG|rcsb pdb:1DSO|rcsb pdb:1DSP|rcsb pdb:1EBE|rcsb pdb:1JCI|rcsb pdb:1JDR|rcsb pdb:1KOK|rcsb pdb:1KRJ|rcsb pdb:1KXM|rcsb pdb:1KXN|rcsb pdb:1MK8|rcsb pdb:1MKQ|rcsb pdb:1MKR|rcsb pdb:1ML2|rcsb pdb:1RYC|rcsb pdb:1S6V|rcsb pdb:1S73|rcsb pdb:1SBM|rcsb pdb:1SDQ|rcsb pdb:1SOG|rcsb pdb:1STQ|rcsb pdb:1U74|rcsb pdb:1U75|rcsb pdb:1Z53|rcsb pdb:1ZBY|rcsb pdb:1ZBZ|rcsb pdb:2ANZ|rcsb pdb:2AQD|rcsb pdb:2AS1|rcsb pdb:2AS2|rcsb pdb:2AS3|rcsb pdb:2AS4|rcsb pdb:2AS6|rcsb pdb:2B0Z|rcsb pdb:2B10|rcsb pdb:2B11|rcsb pdb:2B12|rcsb pdb:2BCN|rcsb pdb:2CCP|rcsb pdb:2CEP|rcsb pdb:2CYP|rcsb pdb:2EUN|rcsb pdb:2EUO|rcsb pdb:2EUP|rcsb pdb:2EUQ|rcsb pdb:2EUR|rcsb pdb:2EUS|rcsb pdb:2EUT|rcsb pdb:2EUU|rcsb pdb:2GB8|rcsb pdb:2IA8|rcsb pdb:2ICV|rcsb pdb:2JTI|rcsb pdb:2N18|rcsb pdb:2PCB|rcsb pdb:2PCC|rcsb pdb:2RBT|rcsb pdb:2RBU|rcsb pdb:2RBV|rcsb pdb:2RBW|rcsb pdb:2RBX|rcsb pdb:2RBY|rcsb pdb:2RBZ|rcsb pdb:2RC0|rcsb pdb:2RC1|rcsb pdb:2RC2|rcsb pdb:2V23|rcsb pdb:2V2E|rcsb pdb:2X07|rcsb pdb:2X08|rcsb pdb:2XIL|rcsb pdb:2XJ5|rcsb pdb:2XJ8|rcsb pdb:2Y5A|rcsb pdb:2YCG|rcsb pdb:3CCP|rcsb pdb:3CCX|rcsb pdb:3E2N|rcsb pdb:3E2O|rcsb pdb:3EXB|rcsb pdb:3M23|rcsb pdb:3M25|rcsb pdb:3M26|rcsb pdb:3M27|rcsb pdb:3M28|rcsb pdb:3M29|rcsb pdb:3M2A|rcsb pdb:1CMU|rcsb pdb:3M2B|rcsb pdb:3M2C|rcsb pdb:3M2D|rcsb pdb:3M2E|rcsb pdb:3M2F|rcsb pdb:3M2G|rcsb pdb:3M2H|rcsb pdb:3M2I|rcsb pdb:3R98|rcsb pdb:3R99|rcsb pdb:4A6Z|rcsb pdb:4A71|rcsb pdb:4A78|rcsb pdb:4A7M|rcsb pdb:4CCP|rcsb pdb:4CCX|rcsb pdb:4CVI|rcsb pdb:4CVJ|rcsb pdb:4JB4|rcsb pdb:4NFG|rcsb pdb:4P4Q|rcsb pdb:4XV4|rcsb pdb:4XV5|rcsb pdb:4XV6|rcsb pdb:4XV7|rcsb pdb:4XV8|rcsb pdb:4XVA|rcsb pdb:5CCP|rcsb pdb:5CIB|rcsb pdb:5CIC|rcsb pdb:5CID|rcsb pdb:5CIE|rcsb pdb:5CIF|rcsb pdb:5CIG|rcsb pdb:5CIH|rcsb pdb:5D6M|rcsb pdb:5EJT|rcsb pdb:5EJX|rcsb pdb:6CCP|rcsb pdb:6H08|rcsb pdb:6P41|rcsb pdb:6P42|rcsb pdb:6P43|rcsb pdb:6Y1T|rcsb pdb:6Y2Y|rcsb pdb:7CCP|sgd:YKR066C(identity)	refseq:NP_004979.3|ensembl:ENSG00000198681(gene)|ensembl:ENST00000356661(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|interpro:IPR002190(MAGE protein)|interpro:IPR021072|interpro:IPR030093|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|rcsb pdb:1W72|rcsb pdb:3BO8|dip:DIP-54794N|entrezgene/locuslink:4100(identity)	-	crc64:A5D26385DA6F0A0B	crc64:544EEB1F9F4E9D33	figure legend:Table EV7|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2015/12/14	2016/02/04	rogid:LkPXY1wuYoCFzMQPSsAtXZrRi8w559292	rogid:6XW3mnTNM3yvOtXmiFbU8Uz3hjA9606	intact-crc:F9FE7993D3F6D283|rigid:VQneuJ3S6d1jG8dpkHfjjzGW/0w	false	tandem tag:n-n	renilla luciferase protein tag:n-n	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q06389	uniprotkb:P01011	intact:EBI-11946|ensemblfungi:YDR373W|uniprotkb:D6VT04	intact:EBI-296557|uniprotkb:Q9UC47|uniprotkb:Q13703|uniprotkb:Q2TU87|uniprotkb:Q2TU88|uniprotkb:Q59GP9|uniprotkb:Q6LBY8|uniprotkb:Q6LDT7|uniprotkb:Q6NSC9|uniprotkb:Q8N177|uniprotkb:Q96DW8|uniprotkb:Q9UNU9|uniprotkb:B3KVQ7|ensembl:ENSP00000376793|ensembl:ENSP00000376795|ensembl:ENSP00000450540	psi-mi:ncs1_yeast(display_long)|uniprotkb:FRQ1(gene name)|psi-mi:FRQ1(display_short)|uniprotkb:NCS1(gene name synonym)|uniprotkb:YDR373W(locus name)|uniprotkb:D9481.6(orf name)	psi-mi:aact_human(display_long)|uniprotkb:Cell growth-inhibiting gene 24/25 protein(gene name synonym)|uniprotkb:SERPINA3(gene name)|psi-mi:SERPINA3(display_short)|uniprotkb:AACT(gene name synonym)|uniprotkb:GIG24(orf name)|uniprotkb:GIG25(orf name)|uniprotkb:Serpin A3(gene name synonym)	psi-mi:"MI:0729"(luminescence based mammalian interactome mapping)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11548254|imex:IM-24995-2735	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YDR373W(gene)|ensemblfungi:YDR373W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0033101"(cellular bud membrane)|go:"GO:0043128"(positive regulation of 1-phosphatidylinositol 4-kinase activity)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR028846|rcsb pdb:1FPW|rcsb pdb:2JU0|reactome:R-SCE-2514859|refseq:NP_010661.3|sgd:S000002781|mint:Q06389|dip:DIP-2733N|sgd:YDR373W(identity)	go:"GO:0006953"(acute-phase response)|refseq:NP_001076.2|ensembl:ENSG00000196136(gene)|ensembl:ENST00000393078(transcript)|ensembl:ENST00000393080(transcript)|ensembl:ENST00000467132(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|reactome:R-HSA-6798695|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0030277"(maintenance of gastrointestinal epithelium)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|interpro:IPR000215(Protease inhibitor I4, serpin)|go:"GO:0006954"(inflammatory response)|interpro:IPR023795|interpro:IPR023796|go:"GO:0010951"(negative regulation of endopeptidase activity)|interpro:IPR036186|interpro:IPR042178|interpro:IPR042185|mint:P01011|rcsb pdb:1AS4|rcsb pdb:1QMN|rcsb pdb:2ACH|rcsb pdb:3CAA|rcsb pdb:3DLW|rcsb pdb:4CAA|rcsb pdb:6HGE|reactome:R-HSA-114608|entrezgene/locuslink:12(identity)	-	crc64:5E9D7F48F8AADA21	-	figure legend:Table EV7|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2015/12/14	2016/02/09	rogid:8mxxTP8CHNx24fQcjCxgDE7xhbs559292	rogid:LTdrRsWwtOm8QvOWZ4h0SO8EuP09606	intact-crc:F79991890DE58BEB|rigid:n9tp04GjADA1tlOpNF09vF0RG90	false	renilla luciferase protein tag:n-n	tandem tag:n-n	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q92997	uniprotkb:P05738	intact:EBI-739789|uniprotkb:O14642|uniprotkb:Q13531|uniprotkb:Q8N5E9|uniprotkb:Q92607|uniprotkb:D3DNT0|intact:EBI-11081380|uniprotkb:B4E3E5|ensembl:ENSP00000316054	intact:EBI-15439|uniprotkb:D6VU02|ensemblfungi:YGL147C	psi-mi:dvl3_human(display_long)|uniprotkb:DVL3(gene name)|psi-mi:DVL3(display_short)|uniprotkb:KIAA0208(gene name synonym)|uniprotkb:DSH homolog 3(gene name synonym)	psi-mi:rl9a_yeast(display_long)|uniprotkb:RPL9A(gene name)|psi-mi:RPL9A(display_short)|uniprotkb:RPL9(gene name synonym)|uniprotkb:RPL8A(gene name synonym)|uniprotkb:L8(gene name synonym)|uniprotkb:YL11(gene name synonym)|uniprotkb:RP24(gene name synonym)|uniprotkb:YGL147C(locus name)|uniprotkb:Large ribosomal subunit protein uL6-A(gene name synonym)	psi-mi:"MI:0729"(luminescence based mammalian interactome mapping)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11548267|imex:IM-24995-2736	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004414.3|dip:DIP-34509N|ensembl:ENSG00000161202(gene)|ensembl:ENST00000313143(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002020"(protease binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005109"(frizzled binding)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0038031"(non-canonical Wnt signaling pathway via JNK cascade)|go:"GO:0042493"|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050821"(protein stabilization)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0150012"(positive regulation of neuron projection arborization)|go:"GO:1903827"|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008342(Dishevelled-3 protein, C-terminal)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:Q92997|rcsb pdb:6V7O|rcsb pdb:6ZC6|rcsb pdb:6ZC8|reactome:R-HSA-201681|reactome:R-HSA-201688|reactome:R-HSA-4086400|reactome:R-HSA-4641258|reactome:R-HSA-4641262|reactome:R-HSA-5368598|reactome:R-HSA-5663220|reactome:R-HSA-9673324|entrezgene/locuslink:1857(identity)	sgd:S000003115|refseq:NP_011368.3|ensemblfungi:YGL147C(gene)|ensemblfungi:YGL147C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0019843"(rRNA binding)|go:"GO:0022625"(cytosolic large ribosomal subunit)|interpro:IPR000702(Ribosomal protein L6)|interpro:IPR002359(Ribosomal protein L6, conserved site-2)|interpro:IPR020040|interpro:IPR036789|rcsb pdb:1K5Y|rcsb pdb:3J16|rcsb pdb:3J6X|rcsb pdb:3J6Y|rcsb pdb:3J77|rcsb pdb:3J78|rcsb pdb:3JCT|rcsb pdb:4U3M|rcsb pdb:4U3N|rcsb pdb:4U3U|rcsb pdb:4U4N|rcsb pdb:4U4O|rcsb pdb:4U4Q|rcsb pdb:4U4R|rcsb pdb:4U4U|rcsb pdb:4U4Y|rcsb pdb:4U4Z|rcsb pdb:4U50|rcsb pdb:4U51|rcsb pdb:4U52|rcsb pdb:4U53|rcsb pdb:4U55|rcsb pdb:4U56|rcsb pdb:4U6F|rcsb pdb:4V4B|rcsb pdb:4V6I|rcsb pdb:4V7F|rcsb pdb:4V7R|rcsb pdb:4V88|rcsb pdb:4V8T|rcsb pdb:4V8Y|rcsb pdb:7NRD|rcsb pdb:4V8Z|rcsb pdb:4V91|rcsb pdb:5APN|rcsb pdb:5APO|rcsb pdb:5DAT|rcsb pdb:5DC3|rcsb pdb:5DGE|rcsb pdb:5DGF|rcsb pdb:5DGV|rcsb pdb:5FCI|rcsb pdb:5FCJ|rcsb pdb:5FL8|rcsb pdb:5GAK|rcsb pdb:5H4P|rcsb pdb:5I4L|rcsb pdb:5JCS|rcsb pdb:5JUO|rcsb pdb:5JUP|rcsb pdb:5JUS|rcsb pdb:5JUT|rcsb pdb:5JUU|rcsb pdb:5LYB|rcsb pdb:5M1J|rcsb pdb:5MC6|rcsb pdb:5MEI|rcsb pdb:5NDG|rcsb pdb:5NDV|rcsb pdb:5NDW|rcsb pdb:5OBM|rcsb pdb:5ON6|rcsb pdb:5T62|rcsb pdb:5T6R|rcsb pdb:5TBW|rcsb pdb:5TGA|rcsb pdb:5TGM|rcsb pdb:5Z3G|rcsb pdb:6ELZ|rcsb pdb:6EM1|rcsb pdb:6EM5|rcsb pdb:6FT6|rcsb pdb:6GQ1|rcsb pdb:6GQB|rcsb pdb:6GQV|rcsb pdb:6HD7|rcsb pdb:6HHQ|rcsb pdb:6I7O|rcsb pdb:6M62|rcsb pdb:6N8J|rcsb pdb:6N8K|rcsb pdb:6N8L|rcsb pdb:6N8M|rcsb pdb:6N8N|rcsb pdb:6N8O|rcsb pdb:6OIG|rcsb pdb:6Q8Y|rcsb pdb:6QIK|rcsb pdb:6QT0|rcsb pdb:6QTZ|rcsb pdb:6R84|rcsb pdb:6R86|rcsb pdb:6R87|rcsb pdb:6RI5|rcsb pdb:6RZZ|rcsb pdb:6S05|rcsb pdb:6S47|rcsb pdb:6SNT|rcsb pdb:6SV4|rcsb pdb:6T4Q|rcsb pdb:6T7I|rcsb pdb:6T7T|rcsb pdb:6T83|rcsb pdb:6TB3|rcsb pdb:6TNU|rcsb pdb:6YLG|rcsb pdb:6YLH|rcsb pdb:6YLX|rcsb pdb:6YLY|rcsb pdb:6Z6J|rcsb pdb:6Z6K|rcsb pdb:7AZY|rcsb pdb:7B7D|rcsb pdb:7BT6|rcsb pdb:7BTB|rcsb pdb:7NRC|dip:DIP-4826N|sgd:YGL147C(identity)	-	-	-	figure legend:Table EV7|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2015/12/14	2016/02/04	rogid:yJ3YIp5IhvKTQwa3bK5yTjNyqXk9606	rogid:TCDvdj9QlqdgRadKyIWG7ane1hw559292	intact-crc:B6F128A47ACB8CFE|rigid:zMFEPUFkowDpfM3kSMjbz6SoM/0	false	renilla luciferase protein tag:n-n	tandem tag:n-n	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P17255	uniprotkb:P43355	intact:EBI-20245|uniprotkb:O74301|uniprotkb:Q9Y7W5|uniprotkb:D6VRG7|ensemblfungi:YDL185W	intact:EBI-740978|ensembl:ENSP00000349085|uniprotkb:O00346|uniprotkb:B2RC81	psi-mi:vata_yeast(display_long)|uniprotkb:VMA1(gene name)|psi-mi:VMA1(display_short)|uniprotkb:CLS8(gene name synonym)|uniprotkb:TFP1(gene name synonym)|uniprotkb:YDL185W(locus name)|uniprotkb:D1286(orf name)|uniprotkb:Vacuolar proton pump subunit A(gene name synonym)	psi-mi:maga1_human(display_long)|uniprotkb:MAGE-1 antigen(gene name synonym)|uniprotkb:Antigen MZ2-E(gene name synonym)|uniprotkb:Cancer/testis antigen 1.1(gene name synonym)|uniprotkb:MAGEA1(gene name)|psi-mi:MAGEA1(display_short)|uniprotkb:MAGE1(gene name synonym)|uniprotkb:MAGE1A(gene name synonym)	psi-mi:"MI:0729"(luminescence based mammalian interactome mapping)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11548293|imex:IM-24995-2738	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010096.1|sgd:S000002344|mint:P17255|ensemblfungi:YDL185W(gene)|ensemblfungi:YDL185W_mRNA(transcript)|go:"GO:0000221"(vacuolar proton-transporting V-type ATPase, V1 domain)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0003677"(DNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006314"(intron homing)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0012505"(endomembrane system)|go:"GO:0016539"(intein-mediated protein splicing)|go:"GO:0044267"(cellular protein metabolic process)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR003586(Hedgehog/intein hint domain, C-terminal)|interpro:IPR003587(Hedgehog/intein hint, N-terminal)|interpro:IPR004042(Intein DOD homing endonuclease)|interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR006141(Intein splicing site)|interpro:IPR006142(Intein)|interpro:IPR007868(Hom-end-associated Hint)|interpro:IPR007869(Homing endonuclease)|interpro:IPR020003|interpro:IPR022878|interpro:IPR023366|interpro:IPR027417|interpro:IPR027434|interpro:IPR030934|interpro:IPR031686|interpro:IPR036121|interpro:IPR036844|rcsb pdb:1DFA|rcsb pdb:1EF0|rcsb pdb:1GPP|rcsb pdb:1JVA|rcsb pdb:1LWS|rcsb pdb:1LWT|rcsb pdb:1UM2|rcsb pdb:1VDE|rcsb pdb:3J9T|rcsb pdb:3J9U|rcsb pdb:3J9V|rcsb pdb:5BW9|rcsb pdb:5D80|rcsb pdb:5VOX|rcsb pdb:5VOY|rcsb pdb:5VOZ|reactome:R-SCE-1222556|reactome:R-SCE-77387|reactome:R-SCE-917977|reactome:R-SCE-9639288|interpro:IPR024034|dip:DIP-2293N|sgd:YDL185W(identity)	refseq:NP_004979.3|ensembl:ENSG00000198681(gene)|ensembl:ENST00000356661(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|interpro:IPR002190(MAGE protein)|interpro:IPR021072|interpro:IPR030093|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|rcsb pdb:1W72|rcsb pdb:3BO8|dip:DIP-54794N|entrezgene/locuslink:4100(identity)	-	crc64:2A4C65D2F59426FD	crc64:544EEB1F9F4E9D33	figure legend:Table EV7|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2015/12/14	2016/02/04	rogid:YdmGZxIMX2IXMHC4EO85uOAf1Hg559292	rogid:6XW3mnTNM3yvOtXmiFbU8Uz3hjA9606	intact-crc:5235218AC8809260|rigid:eU2IYpxCFkXgEheF4T+xo6dsyI0	false	tandem tag:n-n	renilla luciferase protein tag:n-n	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8TAP6	uniprotkb:P13130	intact:EBI-742887|ensembl:ENSP00000262127|uniprotkb:Q658N5|uniprotkb:Q9H9U7|uniprotkb:B0YJB2|uniprotkb:B4DXG5|uniprotkb:B4DZW1	intact:EBI-11523294|uniprotkb:D3DL88|ensemblfungi:YHR139C	psi-mi:cep76_human(display_long)|uniprotkb:CEP76(gene name)|psi-mi:CEP76(display_short)|uniprotkb:C18orf9(gene name synonym)	psi-mi:ss100_yeast(display_long)|uniprotkb:SPS100(gene name)|psi-mi:SPS100(display_short)|uniprotkb:YHR139C(locus name)	psi-mi:"MI:0729"(luminescence based mammalian interactome mapping)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11548280|imex:IM-24995-2737	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_079175.2|ensembl:ENSG00000101624(gene)|ensembl:ENST00000262127(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0046599"(regulation of centriole replication)|interpro:IPR028926|interpro:IPR038765|mint:Q8TAP6|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_001258918.1|entrezgene/locuslink:79959(identity)	interpro:IPR006034(Asparaginase/glutaminase)|refseq:NP_012007.1|sgd:S000001181|ensemblfungi:YHR139C(gene)|ensemblfungi:YHR139C_mRNA(transcript)|go:"GO:0030476"(ascospore wall assembly)|interpro:IPR036152|sgd:YHR139C(identity)	-	-	-	figure legend:Table EV7|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2015/12/14	2016/03/16	rogid:fWzb8oIU35oVWomyDrf8u5sbxUk9606	rogid:ThKMilyLHPEAiJu+3ty4DXcUEE4559292	intact-crc:D4DF328EF9CB7DCC|rigid:YRjep4LcIYNbHrjtIgVJr+fIq6A	false	renilla luciferase protein tag:n-n	tandem tag:n-n	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P29703	uniprotkb:Q8NA61-2	intact:EBI-14814|uniprotkb:D6VXR6|ensemblfungi:YKL019W	intact:EBI-11524851|ensembl:ENSP00000368249|ensembl:ENSP00000480148	psi-mi:fnta_yeast(display_long)|uniprotkb:YKL019W(locus name)|uniprotkb:RAM2(gene name)|psi-mi:RAM2(display_short)|uniprotkb:CAAX farnesyltransferase subunit alpha(gene name synonym)|uniprotkb:Ras proteins prenyltransferase subunit alpha(gene name synonym)|uniprotkb:FTase-alpha(gene name synonym)|uniprotkb:Type I protein geranyl-geranyltransferase subunit alpha(gene name synonym)	psi-mi:q8na61-2(display_long)|uniprotkb:CBY2(gene name)|psi-mi:CBY2(display_short)|uniprotkb:SPERT(gene name synonym)|uniprotkb:Spermatid-associated protein(gene name synonym)	psi-mi:"MI:0729"(luminescence based mammalian interactome mapping)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11548332|imex:IM-24995-2741	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000001502|refseq:NP_012906.3|go:"GO:0004662"(CAAX-protein geranylgeranyltransferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005953"(CAAX-protein geranylgeranyltransferase complex)|go:"GO:0005965"(protein farnesyltransferase complex)|go:"GO:0007323"(peptide pheromone maturation)|go:"GO:0018343"(protein farnesylation)|go:"GO:0018344"(protein geranylgeranylation)|interpro:IPR002088(Protein prenyltransferase, alpha subunit)|reactome:R-SCE-9648002|ensemblfungi:YKL019W(gene)|ensemblfungi:YKL019W_mRNA(transcript)|go:"GO:0004660"(protein farnesyltransferase activity)|go:"GO:0004661"(protein geranylgeranyltransferase activity)|dip:DIP-1233N|mint:P29703|sgd:YKL019W(identity)	intact:EBI-741724(isoform-parent)|ensembl:ENSG00000174015(gene)|ensembl:ENST00000378966(transcript)|ensembl:ENST00000610924(transcript)|uniprotkb:Q8NA61-2(isoform-parent)|entrezgene/locuslink:220082(identity)	-	-	-	figure legend:Table EV7|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2015/12/14	2016/02/04	rogid:u2rtpSuSW9Zd8LHWmniip7r5Ycs559292	rogid:SogYcXGGMYRYzB9xKC5o0pEtsDs9606	intact-crc:45E79668B943764A|rigid:i4d4cxUdwD81HyA2LjGD4Qevni8	false	tandem tag:n-n	renilla luciferase protein tag:n-n	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96HH9	uniprotkb:P25641	intact:EBI-2832937|uniprotkb:Q9H753|uniprotkb:D3DSZ3|uniprotkb:B7Z1F2|uniprotkb:B7Z3R1|uniprotkb:B7Z6D8|uniprotkb:B7Z8T2|ensembl:ENSP00000285689	intact:EBI-375693|uniprotkb:Q8NIL6|uniprotkb:D6VR71|ensemblfungi:YCR068W	psi-mi:grm2b_human(display_long)|uniprotkb:GRAMD2B(gene name)|psi-mi:GRAMD2B(display_short)|uniprotkb:GRAMD3(gene name synonym)|uniprotkb:HCV NS3-transactivated protein 2(gene name synonym)|uniprotkb:NS3TP2(gene name synonym)	psi-mi:atg15_yeast(display_long)|uniprotkb:ATG15(gene name)|psi-mi:ATG15(display_short)|uniprotkb:AUT5(gene name synonym)|uniprotkb:CVT17(gene name synonym)|uniprotkb:YCR068W(locus name)|uniprotkb:YCR68W(orf name)|uniprotkb:Autophagy-related protein 15(gene name synonym)|uniprotkb:Cytoplasm to vacuole targeting protein 17(gene name synonym)	psi-mi:"MI:0729"(luminescence based mammalian interactome mapping)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11548319|imex:IM-24995-2740	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_016865274.1|refseq:NP_001139791.1|refseq:NP_001139792.1|refseq:NP_001139793.1|refseq:NP_001139794.1|refseq:NP_076416.2|refseq:XP_005272120.1|ensembl:ENSG00000155324(gene)|ensembl:ENST00000285689(transcript)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0042802"(identical protein binding)|interpro:IPR004182(GRAM)|interpro:IPR011993(Pleckstrin homology-type)|entrezgene/locuslink:65983(identity)	ensemblfungi:YCR068W_mRNA(transcript)|go:"GO:0000425"(pexophagy)|go:"GO:0004620"(phospholipase activity)|go:"GO:0004806"(triglyceride lipase activity)|go:"GO:0005775"(vacuolar lumen)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006624"(vacuolar protein processing)|go:"GO:0006660"(phosphatidylserine catabolic process)|go:"GO:0006914"(autophagy)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0030397"(membrane disassembly)|go:"GO:0032585"(multivesicular body membrane)|go:"GO:0034496"(multivesicular body membrane disassembly)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0046461"(neutral lipid catabolic process)|interpro:IPR002921(Lipase, class 3)|interpro:IPR029058|ensemblfungi:YCR068W(gene)|refseq:NP_009994.2|sgd:S000000664|dip:DIP-5001N|sgd:YCR068W(identity)	-	-	crc64:B56ABAB72B999019	figure legend:Table EV7|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2015/12/14	2016/02/04	rogid:6UkVJddV5/mHpLX/rk00jMwCA+k9606	rogid:ttgDIIQIdYUuP+ME547oz2gZuEA559292	intact-crc:A2BC9FEFF9DB7E88|rigid:O18CJOhduXKvpXhJ8XULUTU5KbU	false	renilla luciferase protein tag:n-n	tandem tag:n-n	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96EV8	uniprotkb:P32610	intact:EBI-465804|uniprotkb:Q5THY3|uniprotkb:Q5THY4|uniprotkb:Q96NV2|intact:EBI-28986386|ensembl:ENSP00000341680|uniprotkb:Q9H0U2|uniprotkb:Q9H3J5|uniprotkb:A8K3V3	intact:EBI-20264|uniprotkb:D3DLJ9|ensemblfungi:YEL051W	psi-mi:dtbp1_human(display_long)|uniprotkb:My031(orf name)|uniprotkb:DTNBP1(gene name)|psi-mi:DTNBP1(display_short)|uniprotkb:Dystrobrevin-binding protein 1(gene name synonym)|uniprotkb:Hermansky-Pudlak syndrome 7 protein(gene name synonym)|uniprotkb:Dysbindin-1(gene name synonym)|uniprotkb:BLOC1S8(gene name synonym)|uniprotkb:Biogenesis of lysosome-related organelles complex 1 subunit 8(gene name synonym)	psi-mi:vatd_yeast(display_long)|uniprotkb:VMA8(gene name)|psi-mi:VMA8(display_short)|uniprotkb:YEL051W(locus name)|uniprotkb:SYGP-ORF11(orf name)|uniprotkb:Vacuolar proton pump subunit D(gene name synonym)	psi-mi:"MI:0729"(luminescence based mammalian interactome mapping)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11548371|imex:IM-24995-2744	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000047579(gene)|ensembl:ENST00000344537(transcript)|go:"GO:0001956"(positive regulation of neurotransmitter secretion)|go:"GO:0005634"(nucleus)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007596"(blood coagulation)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014059"(regulation of dopamine secretion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016528"(sarcoplasm)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0030496"(midbody)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032438"(melanosome organization)|go:"GO:0033162"(melanosome membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0043005"(neuron projection)|go:"GO:0043197"(dendritic spine)|go:"GO:0005737"(cytoplasm)|go:"GO:0043506"(regulation of JUN kinase activity)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0060155"(platelet dense granule organization)|go:"GO:0060159"(regulation of dopamine receptor signaling pathway)|go:"GO:0071901"(negative regulation of protein serine/threonine kinase activity)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR007531(Dysbindin)|reactome:R-HSA-432722|go:"GO:0048490"(anterograde synaptic vesicle transport)|refseq:NP_115498.2|refseq:NP_898861.1|refseq:NP_001258597.1|refseq:NP_001258598.1|ensembl:ENST00000338950|ensembl:ENSP00000344718|ensembl:ENSP00000341680|refseq:NP_001258596.1|entrezgene/locuslink:84062(identity)	refseq:NP_010863.1|sgd:S000000777|ensemblfungi:YEL051W(gene)|ensemblfungi:YEL051W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0016471"(vacuolar proton-transporting V-type ATPase complex)|go:"GO:0033176"(proton-transporting V-type ATPase complex)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR002699(ATPase, V1/A1 complex, subunit D)|rcsb pdb:3J9T|rcsb pdb:3J9U|rcsb pdb:3J9V|rcsb pdb:4RND|rcsb pdb:5BW9|rcsb pdb:5D80|rcsb pdb:5VOX|rcsb pdb:5VOY|rcsb pdb:5VOZ|rcsb pdb:6O7V|rcsb pdb:6O7W|rcsb pdb:6O7X|reactome:R-SCE-1222556|reactome:R-SCE-6798695|reactome:R-SCE-77387|reactome:R-SCE-917977|reactome:R-SCE-9639288|dip:DIP-2959N|mint:P32610|sgd:YEL051W(identity)	-	-	crc64:FDE93E1FAF0AEC5B	figure legend:Table EV7|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2015/12/14	2016/02/04	rogid:PBwxp1vobm9l5yGoqev97lzkMHg9606	rogid:rrwRno7lCnDeTNwawONkGwV8Hkg559292	intact-crc:6DAFEEA61AEC9D82|rigid:SIIATUHtRJRLyRIKE2irBgkXGmA	false	renilla luciferase protein tag:n-n	tandem tag:n-n	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P32502	uniprotkb:Q96HA8	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	intact:EBI-741158|uniprotkb:B4DE68|uniprotkb:Q9NW95|ensembl:ENSP00000287387	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:ntaq1_human(display_long)|uniprotkb:NTAQ1(gene name)|psi-mi:NTAQ1(display_short)|uniprotkb:C8orf32(gene name synonym)|uniprotkb:Protein NH2-terminal glutamine deamidase(gene name synonym)|uniprotkb:WDYHV motif-containing protein 1(gene name synonym)|uniprotkb:WDYHV1(gene name synonym)	psi-mi:"MI:0729"(luminescence based mammalian interactome mapping)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11548358|imex:IM-24995-2743	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731|sgd:YLR291C(identity)	refseq:NP_060494.1|refseq:NP_001269953.1|ensembl:ENSG00000156795(gene)|ensembl:ENST00000287387(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0008418"(protein-N-terminal asparagine amidohydrolase activity)|interpro:IPR023128|interpro:IPR037132|interpro:IPR039733|mint:Q96HA8|rcsb pdb:3C9Q|rcsb pdb:4W79|rcsb pdb:6KGJ|go:"GO:0070773"(protein-N-terminal glutamine amidohydrolase activity)|entrezgene/locuslink:55093(identity)	-	crc64:A5409FAF1594854C	-	figure legend:Table EV7|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2015/12/14	2016/02/04	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	rogid:RKX6ww+Z/Zw6bmOXa0r8C0mxlvc9606	intact-crc:D2FD39ADA7BFB7A4|rigid:xjYCO1ebvGyeUhWxDtdeHBql7yk	false	tandem tag:n-n	renilla luciferase protein tag:n-n	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P14373	uniprotkb:P32464	intact:EBI-719493|uniprotkb:A2BE15|uniprotkb:Q5RJA8|uniprotkb:Q5ST26|uniprotkb:Q6LA73|uniprotkb:Q6NXR9|uniprotkb:Q9BZY6|uniprotkb:Q9UJL3|ensembl:ENSP00000383555|ensembl:ENSP00000392787|ensembl:ENSP00000405229|ensembl:ENSP00000414793|ensembl:ENSP00000366404	intact:EBI-8859|ensemblfungi:YKL189W|uniprotkb:D6VX11	psi-mi:tri27_human(display_long)|uniprotkb:TRIM27(gene name)|psi-mi:TRIM27(display_short)|uniprotkb:RNF76(gene name synonym)|uniprotkb:RFP(gene name synonym)|uniprotkb:Ret finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 27(gene name synonym)|uniprotkb:RING finger protein 76(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM27(gene name synonym)	psi-mi:hym1_yeast(display_long)|uniprotkb:YKL189W(locus name)|uniprotkb:HYM1(gene name)|psi-mi:HYM1(display_short)	psi-mi:"MI:0729"(luminescence based mammalian interactome mapping)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11548345|imex:IM-24995-2742	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006501.1|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0090281"(negative regulation of calcium ion import)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR020457|interpro:IPR035791|interpro:IPR043136|mint:P14373|reactome:R-HSA-3232142|reactome:R-HSA-9635465|reactome:R-HSA-8948751|ensembl:ENSG00000204713(gene)|ensembl:ENSG00000215641(gene)|ensembl:ENSG00000229006(gene)|ensembl:ENSG00000234495(gene)|ensembl:ENSG00000237071(gene)|ensembl:ENST00000377199(transcript)|ensembl:ENST00000400720(transcript)|ensembl:ENST00000431123(transcript)|ensembl:ENST00000435528(transcript)|ensembl:ENST00000437160(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001650"(fibrillar center)|go:"GO:0002820"(negative regulation of adaptive immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|entrezgene/locuslink:5987(identity)	ensemblfungi:YKL189W(gene)|ensemblfungi:YKL189W_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0000920"(septum digestion after cytokinesis)|go:"GO:0005933"(cellular bud)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007118"(budding cell apical bud growth)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043332"(mating projection tip)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0044732"(mitotic spindle pole body)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013878(Mo25-like)|interpro:IPR016024(Armadillo-type fold)|reactome:R-SCE-6798695|refseq:NP_012732.1|sgd:S000001672|mint:P32464|dip:DIP-5425N|sgd:YKL189W(identity)	-	-	crc64:F48860754C892BA9	figure legend:Table EV7|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2015/12/14	2016/02/04	rogid:dsfH5OUghD8KSaTz1SFw9OYVTK49606	rogid:pOlQFFuYgFzmqf3ZGUVkBj9h7Uc559292	intact-crc:0573858F68ECAA27|rigid:2igrLlIUhR+ddAP5LUqSOBOq6IE	false	renilla luciferase protein tag:n-n	tandem tag:n-n	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P32902	uniprotkb:Q8NA61-2	intact:EBI-16248|ensemblfungi:YHL004W|uniprotkb:D3DKR0	intact:EBI-11524851|ensembl:ENSP00000368249|ensembl:ENSP00000480148	psi-mi:rt04_yeast(display_long)|uniprotkb:MRP4(gene name)|psi-mi:MRP4(display_short)|uniprotkb:MRP4A(gene name synonym)|uniprotkb:Mitochondrial small ribosomal subunit protein uS2m(gene name synonym)|uniprotkb:YHL004W(locus name)	psi-mi:q8na61-2(display_long)|uniprotkb:CBY2(gene name)|psi-mi:CBY2(display_short)|uniprotkb:SPERT(gene name synonym)|uniprotkb:Spermatid-associated protein(gene name synonym)	psi-mi:"MI:0729"(luminescence based mammalian interactome mapping)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11548399|imex:IM-24995-2746	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YHL004W(gene)|ensemblfungi:YHL004W_mRNA(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR001865(Ribosomal protein S2)|interpro:IPR005706(Ribosomal protein S2, bacterial-type)|interpro:IPR018130|interpro:IPR023591|rcsb pdb:5MRC|rcsb pdb:5MRE|rcsb pdb:5MRF|refseq:NP_011859.1|sgd:S000000996|dip:DIP-5035N|mint:P32902|sgd:YHL004W(identity)	intact:EBI-741724(isoform-parent)|ensembl:ENSG00000174015(gene)|ensembl:ENST00000378966(transcript)|ensembl:ENST00000610924(transcript)|uniprotkb:Q8NA61-2(isoform-parent)|entrezgene/locuslink:220082(identity)	-	crc64:81A1CB33134BC559	-	figure legend:Table EV7|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2015/12/14	2016/02/04	rogid:BlL3W6HUN+uAKF/AxwlV1zT5YZQ559292	rogid:SogYcXGGMYRYzB9xKC5o0pEtsDs9606	intact-crc:7D03CF5460131DFD|rigid:efXubap58mIr57EWgtd3RkV3SoM	false	tandem tag:n-n	renilla luciferase protein tag:n-n	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P32902	uniprotkb:Q9H892-2	intact:EBI-16248|ensemblfungi:YHL004W|uniprotkb:D3DKR0	intact:EBI-10274410|ensembl:ENSP00000315160|ensembl:ENSP00000435291	psi-mi:rt04_yeast(display_long)|uniprotkb:MRP4(gene name)|psi-mi:MRP4(display_short)|uniprotkb:MRP4A(gene name synonym)|uniprotkb:Mitochondrial small ribosomal subunit protein uS2m(gene name synonym)|uniprotkb:YHL004W(locus name)	psi-mi:q9h892-2(display_long)|uniprotkb:TTC12(gene name)|psi-mi:TTC12(display_short)	psi-mi:"MI:0729"(luminescence based mammalian interactome mapping)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11548412|imex:IM-24995-2747	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YHL004W(gene)|ensemblfungi:YHL004W_mRNA(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR001865(Ribosomal protein S2)|interpro:IPR005706(Ribosomal protein S2, bacterial-type)|interpro:IPR018130|interpro:IPR023591|rcsb pdb:5MRC|rcsb pdb:5MRE|rcsb pdb:5MRF|refseq:NP_011859.1|sgd:S000000996|dip:DIP-5035N|mint:P32902|sgd:YHL004W(identity)	ensembl:ENSG00000149292(gene)|ensembl:ENST00000314756(transcript)|ensembl:ENST00000494714(transcript)|intact:EBI-2548354(isoform-parent)|uniprotkb:Q9H892-2(isoform-parent)|entrezgene/locuslink:54970(identity)	-	crc64:81A1CB33134BC559	isoform-comment:May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay.	figure legend:Table EV7|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2015/12/14	2016/02/04	rogid:BlL3W6HUN+uAKF/AxwlV1zT5YZQ559292	rogid:OEjSVGC92wY/pn1l/B1t3wDa3s89606	intact-crc:B769371198C802C7|rigid:zk8lMiY4sUBQ9FH8bwjlD/O+26U	false	tandem tag:n-n	renilla luciferase protein tag:n-n	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P32902	uniprotkb:Q7Z6G3-2	intact:EBI-16248|ensemblfungi:YHL004W|uniprotkb:D3DKR0	intact:EBI-10172876|ensembl:ENSP00000457354|intact:EBI-14062040	psi-mi:rt04_yeast(display_long)|uniprotkb:MRP4(gene name)|psi-mi:MRP4(display_short)|uniprotkb:MRP4A(gene name synonym)|uniprotkb:Mitochondrial small ribosomal subunit protein uS2m(gene name synonym)|uniprotkb:YHL004W(locus name)	psi-mi:q7z6g3-2(display_long)|uniprotkb:EFCBP2(gene name synonym)|uniprotkb:Neuronal calcium-binding protein 2(gene name synonym)|uniprotkb:Synaptotagmin-interacting protein 2(gene name synonym)|uniprotkb:NECAB2(gene name)|psi-mi:NECAB2(display_short)	psi-mi:"MI:0729"(luminescence based mammalian interactome mapping)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11548384|imex:IM-24995-2745	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YHL004W(gene)|ensemblfungi:YHL004W_mRNA(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR001865(Ribosomal protein S2)|interpro:IPR005706(Ribosomal protein S2, bacterial-type)|interpro:IPR018130|interpro:IPR023591|rcsb pdb:5MRC|rcsb pdb:5MRE|rcsb pdb:5MRF|refseq:NP_011859.1|sgd:S000000996|dip:DIP-5035N|mint:P32902|sgd:YHL004W(identity)	ensembl:ENSG00000103154(gene)|ensembl:ENST00000565691(transcript)|uniprotkb:Q7Z6G3-2(isoform-parent)|intact:EBI-950070(isoform-parent)|entrezgene/locuslink:54550(identity)	-	crc64:81A1CB33134BC559	-	figure legend:Table EV7|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2015/12/14	2016/02/04	rogid:BlL3W6HUN+uAKF/AxwlV1zT5YZQ559292	rogid:4S7oIx6h+mKzV3EPxqcfMNqaNko9606	intact-crc:35661244314B63CD|rigid:m58Zj9qZ8WkdvEdqLw8LDRMDctM	false	tandem tag:n-n	sufficient binding region:65-303|renilla luciferase protein tag:n-n	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P38260	uniprotkb:P11142	intact:EBI-21563|uniprotkb:D6VQA0|ensemblfungi:YBR101C	intact:EBI-351896|uniprotkb:Q9H3R6|ensembl:ENSP00000227378|ensembl:ENSP00000432083|ensembl:ENSP00000437125	psi-mi:fes1_yeast(display_long)|uniprotkb:YBR101C(locus name)|uniprotkb:YBR0830(orf name)|uniprotkb:Factor exchange for SSA1 protein 1(gene name synonym)|uniprotkb:FES1(gene name)|psi-mi:FES1(display_short)	psi-mi:hsp7c_human(display_long)|uniprotkb:HSPA8(gene name)|psi-mi:HSPA8(display_short)|uniprotkb:HSC70(gene name synonym)|uniprotkb:HSP73(gene name synonym)|uniprotkb:HSPA10(gene name synonym)|uniprotkb:Heat shock 70 kDa protein 8(gene name synonym)|uniprotkb:Lipopolysaccharide-associated protein 1(gene name synonym)	psi-mi:"MI:0729"(luminescence based mammalian interactome mapping)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11548451|imex:IM-24995-2750	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000000305|refseq:NP_009659.3|mint:P38260|dip:DIP-4918N|ensemblfungi:YBR101C(gene)|ensemblfungi:YBR101C_mRNA(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006417"(regulation of translation)|go:"GO:0071629"(cytoplasm protein quality control by the ubiquitin-proteasome system)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013918(Nucleotide exchange factor Fes1)|interpro:IPR016024(Armadillo-type fold)|sgd:YBR101C(identity)	refseq:NP_006588.1|refseq:NP_694881.1|refseq:XP_011541100.1|ensembl:ENSG00000109971(gene)|ensembl:ENST00000227378(transcript)|ensembl:ENST00000532636(transcript)|ensembl:ENST00000534624(transcript)|go:"GO:0000974"(Prp19 complex)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006397"(mRNA processing)|go:"GO:0006457"(protein folding)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008380"(RNA splicing)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030425"(dendrite)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042026"(protein refolding)|go:"GO:0042470"(melanosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0043195"(terminal bouton)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044829"(positive regulation by host of viral genome replication)|go:"GO:0045296"(cadherin binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0055131"(C3HC4-type RING finger domain binding)|go:"GO:0061024"(membrane organization)|go:"GO:0061202"(clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane)|go:"GO:0061635"(regulation of protein complex stability)|go:"GO:0061684"(chaperone-mediated autophagy)|go:"GO:0061738"(late endosomal microautophagy)|go:"GO:0061740"(protein targeting to lysosome involved in chaperone-mediated autophagy)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0098575"(lumenal side of lysosomal membrane)|go:"GO:0098684"(photoreceptor ribbon synapse)|go:"GO:0098690"(glycinergic synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099175"(regulation of postsynapse organization)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099634"(postsynaptic specialization membrane)|go:"GO:0101031"(chaperone complex)|go:"GO:0140545"(protein disaggregase activity)|go:"GO:0140597"(protein carrier chaperone)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902904"(negative regulation of supramolecular fiber organization)|go:"GO:1904589"(regulation of protein import)|go:"GO:1904764"(chaperone-mediated autophagy translocation complex disassembly)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1990832"(slow axonal transport)|go:"GO:1990833"(clathrin-uncoating ATPase activity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|mint:P11142|rcsb pdb:3AGY|rcsb pdb:3AGZ|rcsb pdb:3ESK|rcsb pdb:3FZF|rcsb pdb:3FZH|rcsb pdb:3FZK|rcsb pdb:3FZL|rcsb pdb:3FZM|rcsb pdb:3LDQ|rcsb pdb:3M3Z|rcsb pdb:4H5N|rcsb pdb:4H5R|rcsb pdb:4H5T|rcsb pdb:4H5V|rcsb pdb:4H5W|rcsb pdb:4HWI|rcsb pdb:4KBQ|rcsb pdb:5AQF|rcsb pdb:5AQG|rcsb pdb:5AQH|rcsb pdb:5AQI|rcsb pdb:5AQJ|rcsb pdb:5AQK|rcsb pdb:5AQL|rcsb pdb:5AQM|rcsb pdb:5AQN|rcsb pdb:5AQO|rcsb pdb:5AQP|rcsb pdb:5AQQ|rcsb pdb:5AQR|rcsb pdb:5AQS|rcsb pdb:5AQT|rcsb pdb:5AQU|rcsb pdb:5AQV|rcsb pdb:6B1I|rcsb pdb:6B1M|rcsb pdb:6B1N|rcsb pdb:6ZYJ|reactome:R-HSA-3371453|reactome:R-HSA-3371497|reactome:R-HSA-3371568|reactome:R-HSA-3371571|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-447041|reactome:R-HSA-450408|reactome:R-HSA-6785807|reactome:R-HSA-6798695|reactome:R-HSA-72163|reactome:R-HSA-8856828|reactome:R-HSA-8876725|reactome:R-HSA-888590|reactome:R-HSA-9613354|reactome:R-HSA-9613829|reactome:R-HSA-9615710|dip:DIP-32874N|entrezgene/locuslink:3312(identity)	-	crc64:4A50D069625BA500	-	figure legend:Table EV7|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2015/12/14	2016/02/04	rogid:swXhGbIfsVTGs+eOqqViPwySpI0559292	rogid:0I+wYut3naJRzzgmMSax/1mZZwA9606	intact-crc:F0895F571A330D2B|rigid:wjVULKBxWaRB64mV9VWXcOKdgDU	false	tandem tag:n-n	sufficient binding region:61-646|renilla luciferase protein tag:n-n	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q5SW96	uniprotkb:P38263	intact:EBI-747813|uniprotkb:A2BHI5|uniprotkb:Q6TQS9|uniprotkb:Q8N2Y0|uniprotkb:Q9UFI9|intact:EBI-28971912|ensembl:ENSP00000363458	intact:EBI-20304|uniprotkb:D6VQA4|ensemblfungi:YBR105C	psi-mi:arh_human(display_long)|uniprotkb:Autosomal recessive hypercholesterolemia protein(gene name synonym)|uniprotkb:LDLRAP1(gene name)|psi-mi:LDLRAP1(display_short)|uniprotkb:ARH(gene name synonym)	psi-mi:gid4_yeast(display_long)|uniprotkb:VID24(gene name)|psi-mi:VID24(display_short)|uniprotkb:YBR105C(locus name)|uniprotkb:YBR0834(orf name)|uniprotkb:GID4(gene name synonym)|uniprotkb:Glucose-induced degradation protein 4(gene name synonym)	psi-mi:"MI:0729"(luminescence based mammalian interactome mapping)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11548466|imex:IM-24995-2751	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000363458|refseq:NP_056442.2|go:"GO:0042982"(amyloid precursor protein metabolic process)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0055037"(recycling endosome)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0090118"(receptor-mediated endocytosis involved in cholesterol transport)|go:"GO:0090205"(positive regulation of cholesterol metabolic process)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905581"(positive regulation of low-density lipoprotein particle clearance)|go:"GO:1905602"(positive regulation of receptor-mediated endocytosis involved in cholesterol transport)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|rcsb pdb:2G30|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8964026|reactome:R-HSA-8964038|ensembl:ENSG00000157978(gene)|ensembl:ENST00000374338(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005883"(neurofilament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030276"(clathrin binding)|go:"GO:0030301"(cholesterol transport)|go:"GO:0030424"(axon)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031623"(receptor internalization)|go:"GO:0034383"(low-density lipoprotein particle clearance)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0035612"(AP-2 adaptor complex binding)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0035650"(AP-1 adaptor complex binding)|go:"GO:0042632"(cholesterol homeostasis)|entrezgene/locuslink:26119(identity)	refseq:NP_009663.1|sgd:S000000309|ensemblfungi:YBR105C(gene)|ensemblfungi:YBR105C_mRNA(transcript)|go:"GO:0005773"(vacuole)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0007039"(protein catabolic process in the vacuole)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034657"(GID complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045721"(negative regulation of gluconeogenesis)|go:"GO:0071596"(ubiquitin-dependent protein catabolic process via the N-end rule pathway)|interpro:IPR018618|rcsb pdb:6SWY|dip:DIP-4502N|mint:P38263|sgd:YBR105C(identity)	-	-	crc64:FF020B239676E0B2	figure legend:Table EV7|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2015/12/14	2016/02/04	rogid:dtBWLcVpVD/R0aKQZr9Nucfa1oo9606	rogid:ag6caXMIP/qIv27yJtSEmlBoI7g559292	intact-crc:BFDA5F046F9BA59A|rigid:fXQk8T6iq+9VLa3t8eummQvUx0o	false	renilla luciferase protein tag:n-n|sufficient binding region:46-308	tandem tag:n-n	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P38732	uniprotkb:O75569	intact:EBI-24379|uniprotkb:D3DKT0|ensemblfungi:YHL039W	intact:EBI-713955|ensembl:ENSP00000318176|uniprotkb:Q53G24|uniprotkb:Q6X7T5|uniprotkb:Q8NDK4|uniprotkb:A8K3I6	psi-mi:efm1_yeast(display_long)|uniprotkb:EFM1(gene name)|psi-mi:EFM1(display_short)|uniprotkb:Elongation factor methyltransferase 1(gene name synonym)|uniprotkb:YHL039W(locus name)	psi-mi:prkra_human(display_long)|uniprotkb:Protein activator of the interferon-induced protein kinase(gene name synonym)|uniprotkb:PKR-associated protein X(gene name synonym)|uniprotkb:PKR-associating protein X(gene name synonym)|uniprotkb:HSD-14(orf name)|uniprotkb:PRKRA(gene name)|psi-mi:PRKRA(display_short)|uniprotkb:RAX(gene name synonym)|uniprotkb:PACT(gene name synonym)|uniprotkb:HSD14(orf name)|uniprotkb:Protein kinase, interferon-inducible double-stranded RNA-dependent activator(gene name synonym)	psi-mi:"MI:0729"(luminescence based mammalian interactome mapping)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11548481|imex:IM-24995-2752	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011824.1|sgd:S000001031|dip:DIP-6582N|mint:P38732|ensemblfungi:YHL039W(gene)|ensemblfungi:YHL039W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0018026"(peptidyl-lysine monomethylation)|go:"GO:0018027"(peptidyl-lysine dimethylation)|interpro:IPR001214(SET)|interpro:IPR017119(Ribosomal lysine methyltransferase 1)|interpro:IPR044432|sgd:YHL039W(identity)	go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006955"(immune response)|go:"GO:0008047"(enzyme activator activity)|ensembl:ENSG00000180228(gene)|ensembl:ENST00000325748(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030422"(production of siRNA involved in RNA interference)|go:"GO:0031054"(pre-miRNA processing)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035196"(production of miRNAs involved in gene silencing by miRNA)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042474"(middle ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:0050821"(protein stabilization)|go:"GO:0070578"(RISC-loading complex)|go:"GO:0070883"(pre-miRNA binding)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR032478|interpro:IPR033363|interpro:IPR044465|interpro:IPR044466|interpro:IPR044467|mint:O75569|rcsb pdb:2DIX|reactome:R-HSA-203927|reactome:R-HSA-426486|refseq:NP_001132989.1|refseq:NP_001132990.1|refseq:NP_003681.1|dip:DIP-41809N|entrezgene/locuslink:8575(identity)	-	crc64:84BC2D3A204D9D29	-	figure legend:Table EV7|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2015/12/14	2016/02/04	rogid:e5E4ijHZAIzzKWrxCzPqifR2v8U559292	rogid:tZfziopZlC+1d3De97G3kDY+Tog9606	intact-crc:76F9B40859E63043|rigid:a/LTA+bxGClszC704i1ljQY/RaQ	false	tandem tag:n-n	renilla luciferase protein tag:n-n	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P39724	uniprotkb:Q15437	intact:EBI-2343154|uniprotkb:D6VPH0|ensemblfungi:YAL046C	intact:EBI-742673|uniprotkb:Q5W183|uniprotkb:Q9BS15|uniprotkb:Q9BSI2|uniprotkb:Q9H1D7|intact:EBI-1048165|uniprotkb:Q503A9|uniprotkb:D3DW33|ensembl:ENSP00000262544|ensembl:ENSP00000338844|ensembl:ENSP00000366685|ensembl:ENSP00000497473	psi-mi:bol3_yeast(display_long)|uniprotkb:BOL3(gene name)|psi-mi:BOL3(display_short)|uniprotkb:AIM1(gene name synonym)|uniprotkb:Altered inheritance of mitochondria protein 1(gene name synonym)|uniprotkb:YAL046C(locus name)	psi-mi:sc23b_human(display_long)|uniprotkb:SEC23-related protein B(gene name synonym)|uniprotkb:SEC23B(gene name)|psi-mi:SEC23B(display_short)	psi-mi:"MI:0729"(luminescence based mammalian interactome mapping)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11548507|imex:IM-24995-2754	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009353.1|sgd:S000000044|interpro:IPR002634(BolA-like protein)|interpro:IPR036065|mint:P39724|ensemblfungi:YAL046C(gene)|ensemblfungi:YAL046C_mRNA(transcript)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0106035"(protein maturation by [4Fe-4S] cluster transfer)|sgd:YAL046C(identity)	refseq:NP_001166216.1|refseq:NP_006354.2|refseq:NP_116780.1|refseq:NP_116781.1|ensembl:ENSG00000101310(gene)|ensembl:ENST00000262544(transcript)|ensembl:ENST00000336714(transcript)|ensembl:ENST00000377465(transcript)|ensembl:ENST00000650089(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008270"(zinc ion binding)|go:"GO:0012505"(endomembrane system)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0090110"(COPII-coated vesicle cargo loading)|go:"GO:0070971"(endoplasmic reticulum exit site)|interpro:IPR006895(Zinc finger, Sec23/Sec24-type)|interpro:IPR006896(Sec23/Sec24 trunk region)|interpro:IPR006900(Sec23/Sec24 helical region)|interpro:IPR007123(Gelsolin region)|interpro:IPR012990(Sec23/Sec24 beta-sandwich)|interpro:IPR029006|interpro:IPR036174|interpro:IPR036175|interpro:IPR036180|interpro:IPR036465|interpro:IPR037364|interpro:IPR037550|mint:Q15437|refseq:XP_016883082.1|entrezgene/locuslink:10483(identity)	-	-	-	figure legend:Table EV7|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2015/12/14	2016/02/04	rogid:MLrW6Iu4YKXf87O1cyx5bY03VdE559292	rogid:+3KZ/1jjziSgJRcr81Axquofkl49606	intact-crc:C3C9DBA123487F33|rigid:8MkNnnAeJJBcyFBfag9U5MtleHo	false	tandem tag:n-n	renilla luciferase protein tag:n-n	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9BYV6-2	uniprotkb:P38886	intact:EBI-11522718|ensembl:ENSP00000297348	intact:EBI-15949|ensemblfungi:YHR200W|uniprotkb:D3DLE9	psi-mi:q9byv6-2(display_long)|uniprotkb:TRIM55(gene name)|psi-mi:TRIM55(display_short)|uniprotkb:MURF2(gene name synonym)|uniprotkb:Muscle-specific RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 29(gene name synonym)|uniprotkb:RNF29(gene name synonym)|uniprotkb:p50(isoform synonym)	psi-mi:rpn10_yeast(display_long)|uniprotkb:RPN10(gene name)|psi-mi:RPN10(display_short)|uniprotkb:MCB1(gene name synonym)|uniprotkb:SUN1(gene name synonym)|uniprotkb:YHR200W(locus name)	psi-mi:"MI:0729"(luminescence based mammalian interactome mapping)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11548494|imex:IM-24995-2753	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-2341179(isoform-parent)|uniprotkb:Q9BYV6-2(isoform-parent)|ensembl:ENSG00000147573(gene)|ensembl:ENST00000353317(transcript)|entrezgene/locuslink:84675(identity)	ensemblfungi:YHR200W(gene)|ensemblfungi:YHR200W_mRNA(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|sgd:S000001243|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0036435"(K48-linked polyubiquitin modification-dependent protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043248"(proteasome assembly)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR027040|interpro:IPR036465|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5LN1|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5MPD|rcsb pdb:5MPE|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|refseq:NP_012070.3|dip:DIP-2100N|mint:P38886|sgd:YHR200W(identity)	-	-	crc64:8A05198B0CD7C0C3	figure legend:Table EV7|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2015/12/14	2016/02/04	rogid:9t8UhK+Z1yBqjnQrOqPD76NuXGg9606	rogid:Lg2bjPWMUcvXdLDZZMWFWyXbCcA559292	intact-crc:E244545B4C51D029|rigid:YoDMoSc/LsIPVqeFajJU5v39FdY	false	renilla luciferase protein tag:n-n	tandem tag:n-n	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96BA8	uniprotkb:P46956	intact:EBI-6942903|ensembl:ENSP00000481956|intact:MINT-268046|intact:MINT-8162577|uniprotkb:Q8N2D5|uniprotkb:Q96CP0	intact:EBI-13337|uniprotkb:E9P8T7|ensemblfungi:YJL117W|uniprotkb:D6VW67	psi-mi:cr3l1_human(display_long)|uniprotkb:CREB3L1(gene name)|psi-mi:CREB3L1(display_short)|uniprotkb:OASIS(gene name synonym)|uniprotkb:PSEC0238(orf name)|uniprotkb:Old astrocyte specifically-induced substance(gene name synonym)	psi-mi:pho86_yeast(display_long)|uniprotkb:PHO86(gene name)|psi-mi:PHO86(display_short)|uniprotkb:J0744(orf name)|uniprotkb:YJL117W(locus name)	psi-mi:"MI:0729"(luminescence based mammalian interactome mapping)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11548546|imex:IM-24995-2757	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157613(gene)|ensembl:ENST00000621158(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0070278"(extracellular matrix constituent secretion)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029805|mint:Q96BA8|reactome:R-HSA-8874211|refseq:NP_443086.1|entrezgene/locuslink:90993(identity)	refseq:NP_012418.1|sgd:S000003653|interpro:IPR024297|ensemblfungi:YJL117W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006457"(protein folding)|go:"GO:0006817"(phosphate ion transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0010966"(regulation of phosphate transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0051082"(unfolded protein binding)|ensemblfungi:YJL117W(gene)|mint:P46956|dip:DIP-2769N|sgd:YJL117W(identity)	-	comment:mint|function:"Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE"	crc64:1CB19C9184BF1C48	figure legend:Table EV7|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2015/12/14	2016/02/04	rogid:sMWUFmBeBBCO+T0Y2CuB/un1lBg9606	rogid:JITWReptfMoij1Uy6y1e3Oa6dAs559292	intact-crc:80A3A36B2D2E274D|rigid:zNFUhUB559mW5v40Np8eyOmhspM	false	renilla luciferase protein tag:n-n	tandem tag:n-n	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8TAP6	uniprotkb:P46948	intact:EBI-742887|ensembl:ENSP00000262127|uniprotkb:Q658N5|uniprotkb:Q9H9U7|uniprotkb:B0YJB2|uniprotkb:B4DXG5|uniprotkb:B4DZW1	intact:EBI-1788|uniprotkb:D6VUX7|ensemblfungi:YGR195W	psi-mi:cep76_human(display_long)|uniprotkb:CEP76(gene name)|psi-mi:CEP76(display_short)|uniprotkb:C18orf9(gene name synonym)	psi-mi:rrp41_yeast(display_long)|uniprotkb:SKI6(gene name)|psi-mi:SKI6(display_short)|uniprotkb:YGR195W(locus name)|uniprotkb:G7587(orf name)|uniprotkb:ECM20(gene name synonym)|uniprotkb:Ribosomal RNA-processing protein 41(gene name synonym)|uniprotkb:Superkiller protein 6(gene name synonym)|uniprotkb:Extracellular mutant protein 20(gene name synonym)|uniprotkb:RRP41(gene name synonym)	psi-mi:"MI:0729"(luminescence based mammalian interactome mapping)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11548533|imex:IM-24995-2756	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_079175.2|ensembl:ENSG00000101624(gene)|ensembl:ENST00000262127(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0046599"(regulation of centriole replication)|interpro:IPR028926|interpro:IPR038765|mint:Q8TAP6|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_001258918.1|entrezgene/locuslink:79959(identity)	sgd:S000003427|refseq:NP_011711.3|dip:DIP-2083N|mint:P46948|ensemblfungi:YGR195W(gene)|ensemblfungi:YGR195W_mRNA(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034473"(U1 snRNA 3'-end processing)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0034476"(U5 snRNA 3'-end processing)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071039"(nuclear polyadenylation-dependent CUT catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345|rcsb pdb:2WP8|rcsb pdb:4IFD|rcsb pdb:4OO1|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5G06|rcsb pdb:5JEA|rcsb pdb:5K36|rcsb pdb:5OKZ|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-429958|reactome:R-SCE-450385|reactome:R-SCE-450513|reactome:R-SCE-6791226|sgd:YGR195W(identity)	-	-	crc64:C80EFFB528A43044	figure legend:Table EV7|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2015/12/14	2016/02/04	rogid:fWzb8oIU35oVWomyDrf8u5sbxUk9606	rogid:I7vEo0EUB1jZO+3v12H0LwVbgmo559292	intact-crc:91F2F97364BC3A04|rigid:5TWeomSSqBF09jLn+neEbi3/SeA	false	renilla luciferase protein tag:n-n	tandem tag:n-n	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8N5R6	uniprotkb:P40560	intact:EBI-740841|intact:EBI-953781|uniprotkb:B3KQ49|uniprotkb:A8K3U4|uniprotkb:A8MPQ6|uniprotkb:A8MV61|uniprotkb:A8MVU9|uniprotkb:Q9H5Q6|uniprotkb:Q8TAX6|intact:EBI-2320546|intact:EBI-11522976	intact:EBI-24911|uniprotkb:D6VVT0|ensemblfungi:YIL001W	psi-mi:ccd33_human(display_long)|uniprotkb:CCDC33(gene name)|psi-mi:CCDC33(display_short)|uniprotkb:Cancer/testis antigen 61(gene name synonym)	psi-mi:yia1_yeast(display_long)|uniprotkb:YIA1W(orf name)|uniprotkb:YIL001W(locus name)	psi-mi:"MI:0729"(luminescence based mammalian interactome mapping)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11548520|imex:IM-24995-2755	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_079331.3|interpro:IPR000008(C2 calcium-dependent membrane targeting)|go:"GO:0005777"(peroxisome)|refseq:NP_001274110.1|refseq:NP_877592.2|mint:Q8N5R6|interpro:IPR035892|interpro:IPR039889|entrezgene/locuslink:80125(identity)	sgd:S000001263|refseq:NP_012265.3|dip:DIP-1375N|ensemblfungi:YIL001W(gene)|ensemblfungi:YIL001W_mRNA(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0005737"(cytoplasm)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR036770|interpro:IPR044515|sgd:YIL001W(identity)	-	-	-	figure legend:Table EV7|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2015/12/14	2021/11/30	rogid:eEIn7pQyfdHWx8TeLJpYy0i/gww9606	rogid:IOv6oxjYJ3W/jLnmIcM03RDQ8Ww559292	intact-crc:0D688562DE19494E|rigid:pxGUZW0PhxoZskEkamFgZBgxPHE	false	renilla luciferase protein tag:n-n	tandem tag:n-n	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:A0A024R4Q5	uniprotkb:P53900	intact:EBI-11527449	intact:EBI-13246|uniprotkb:D6W130|ensemblfungi:YNL153C	psi-mi:a0a024r4q5_human(display_long)|uniprotkb:hCG_20946(orf name)|uniprotkb:TFPT(gene name)|psi-mi:TFPT(display_short)	psi-mi:pfd4_yeast(display_long)|uniprotkb:GIM3(gene name)|psi-mi:GIM3(display_short)|uniprotkb:PFD4(gene name synonym)|uniprotkb:YNL153C(locus name)|uniprotkb:N1761(orf name)|uniprotkb:Genes involved in microtubule biogenesis protein 3(gene name synonym)|uniprotkb:Gim complex subunit 3(gene name synonym)	psi-mi:"MI:0729"(luminescence based mammalian interactome mapping)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11548587|imex:IM-24995-2760	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_037474.1|interpro:IPR033555|go:"GO:0005654"(nucleoplasm)|go:"GO:0006915"(apoptotic process)|entrezgene/locuslink:29844(identity)	refseq:NP_014246.1|sgd:S000005097|mint:P53900|dip:DIP-3000N|ensemblfungi:YNL153C(gene)|ensemblfungi:YNL153C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:0015631"(tubulin binding)|go:"GO:0016272"(prefoldin complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0071629"(cytoplasm protein quality control by the ubiquitin-proteasome system)|interpro:IPR002777(Prefoldin beta-like)|interpro:IPR009053(Prefoldin)|interpro:IPR016661(Prefoldin, subunit 4)|sgd:YNL153C(identity)	-	-	-	figure legend:Table EV7|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2015/12/14	2016/02/04	rogid:juI/3gZemjc0hnXDJ9J+bIQ9pBw9606	rogid:TdRDErsc5xwqaEqpI4SSCW0sCsg559292	intact-crc:F7963A746016DE79|rigid:1lexydUUIaNmP+up2nXxHIJg2AE	false	renilla luciferase protein tag:n-n|sufficient binding region:10-253	tandem tag:n-n	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8N5R6	uniprotkb:Q06543	intact:EBI-740841|intact:EBI-953781|uniprotkb:B3KQ49|uniprotkb:A8K3U4|uniprotkb:A8MPQ6|uniprotkb:A8MV61|uniprotkb:A8MVU9|uniprotkb:Q9H5Q6|uniprotkb:Q8TAX6|intact:EBI-2320546|intact:EBI-11522976	intact:EBI-33132|uniprotkb:D6VYP1|ensemblfungi:YLR243W	psi-mi:ccd33_human(display_long)|uniprotkb:CCDC33(gene name)|psi-mi:CCDC33(display_short)|uniprotkb:Cancer/testis antigen 61(gene name synonym)	psi-mi:gpn3_yeast(display_long)|uniprotkb:GPN3(gene name)|psi-mi:GPN3(display_short)|uniprotkb:YLR243W(locus name)	psi-mi:"MI:0729"(luminescence based mammalian interactome mapping)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11548615|imex:IM-24995-2762	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_079331.3|interpro:IPR000008(C2 calcium-dependent membrane targeting)|go:"GO:0005777"(peroxisome)|refseq:NP_001274110.1|refseq:NP_877592.2|mint:Q8N5R6|interpro:IPR035892|interpro:IPR039889|entrezgene/locuslink:80125(identity)	refseq:NP_013344.1|sgd:S000004233|dip:DIP-1911N|ensemblfungi:YLR243W(gene)|ensemblfungi:YLR243W_mRNA(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007064"(mitotic sister chromatid cohesion)|interpro:IPR004130(Protein of unknown function, ATP binding)|interpro:IPR027417|interpro:IPR030228|sgd:YLR243W(identity)	-	-	crc64:96E478B8DD5988BB	figure legend:Table EV7|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2015/12/14	2021/11/30	rogid:eEIn7pQyfdHWx8TeLJpYy0i/gww9606	rogid:XGJg0/XoYEbfio5kpjB/7Q9Cvjc559292	intact-crc:B56BC40D73611829|rigid:M7pDBzuMW3ZgO/PQHF9jUqOW4og	false	renilla luciferase protein tag:n-n	tandem tag:n-n	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P61289	uniprotkb:Q03020	intact:EBI-355546|uniprotkb:O35563|uniprotkb:P97373|uniprotkb:Q12920|uniprotkb:Q13172|uniprotkb:Q9BQD9|uniprotkb:A8K9A3|ensembl:ENSP00000466794	intact:EBI-29901|uniprotkb:D6W3N2|ensemblfungi:YPL135W	psi-mi:psme3_human(display_long)|uniprotkb:PSME3(gene name)|psi-mi:PSME3(display_short)|uniprotkb:Proteasome activator 28 subunit gamma(gene name synonym)|uniprotkb:Activator of multicatalytic protease subunit 3(gene name synonym)|uniprotkb:11S regulator complex subunit gamma(gene name synonym)|uniprotkb:Ki nuclear autoantigen(gene name synonym)	psi-mi:isu1_yeast(display_long)|uniprotkb:YPL135W(locus name)|uniprotkb:Iron sulfur cluster scaffold protein 1(gene name synonym)|uniprotkb:ISU1(gene name)|psi-mi:ISU1(display_short)|uniprotkb:NUA1(gene name synonym)	psi-mi:"MI:0729"(luminescence based mammalian interactome mapping)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11548602|imex:IM-24995-2761	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005780.2|refseq:NP_789839.1|ensembl:ENSG00000131467(gene)|ensembl:ENST00000590720(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0008537"(proteasome activator complex)|go:"GO:0010950"(positive regulation of endopeptidase activity)|go:"GO:0016020"(membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0061133"(endopeptidase activator activity)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0097371"(MDM2/MDM4 family protein binding)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR003185(Proteasome activator pa28, REG alpha subunit)|interpro:IPR003186(Proteasome activator pa28, REG beta subunit)|interpro:IPR009077(Proteasome activator pa28, REG alpha/beta subunit)|interpro:IPR036252|interpro:IPR036996|interpro:IPR036997|mint:P61289|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|entrezgene/locuslink:10197(identity)	refseq:NP_015190.1|sgd:S000006056|dip:DIP-6556N|mint:Q03020|ensemblfungi:YPL135W(gene)|ensemblfungi:YPL135W_mRNA(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005506"(iron ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR002871(NIF system FeS cluster assembly, NifU, N-terminal)|interpro:IPR011339(ISC system FeS cluster assembly, IscU scaffold)|rcsb pdb:5T0V|rcsb pdb:5TRE|reactome:R-SCE-1362409|sgd:YPL135W(identity)	-	-	crc64:E240845A27D2E9EE	figure legend:Table EV7|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2015/12/14	2016/02/04	rogid:6EQY2Kj3Juf++m4eBDzPWMgbC2k9606	rogid:zpPseOgZoK3cF+mCetzw05ct9Kc559292	intact-crc:78ED7A5B0345C2FF|rigid:dQyLm0cBx4VWs2S9MCLhvoIl1/4	false	renilla luciferase protein tag:n-n	tandem tag:n-n	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O14641	uniprotkb:Q06630	intact:EBI-740850|ensembl:ENSP00000005340|uniprotkb:Q53XM0|uniprotkb:D3DTN3	intact:EBI-36794|uniprotkb:D6VSS5|ensemblfungi:YDR296W	psi-mi:dvl2_human(display_long)|uniprotkb:DSH homolog 2(gene name synonym)|uniprotkb:DVL2(gene name)|psi-mi:DVL2(display_short)	psi-mi:mhr1_yeast(display_long)|uniprotkb:MHR1(gene name)|psi-mi:MHR1(display_short)|uniprotkb:YDR296W(locus name)|uniprotkb:Cross-linked transcription component 1(gene name synonym)|uniprotkb:XTC1(gene name synonym)|uniprotkb:Mitochondrial large ribosomal subunit protein mL67(gene name synonym)	psi-mi:"MI:0729"(luminescence based mammalian interactome mapping)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11548628|imex:IM-24995-2763	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004413.1|ensembl:ENSG00000004975(gene)|ensembl:ENST00000005340(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005109"(frizzled binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0007507"(heart development)|go:"GO:0016235"(aggresome)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044340"(canonical Wnt signaling pathway involved in regulation of cell proliferation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0150012"(positive regulation of neuron projection arborization)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008341(Dishevelled-2 region)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:O14641|rcsb pdb:2REY|rcsb pdb:3CBX|rcsb pdb:3CBY|rcsb pdb:3CBZ|rcsb pdb:3CC0|rcsb pdb:4WIP|rcsb pdb:5LNP|rcsb pdb:5SUY|rcsb pdb:5SUZ|rcsb pdb:6IW3|rcsb pdb:6JCK|reactome:R-HSA-201681|reactome:R-HSA-201688|reactome:R-HSA-2028269|reactome:R-HSA-4086400|reactome:R-HSA-4608870|reactome:R-HSA-4641258|reactome:R-HSA-4641262|reactome:R-HSA-5099900|reactome:R-HSA-5368598|reactome:R-HSA-5663220|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9673324|ensembl:ENSP00000005340|dip:DIP-34433N|entrezgene/locuslink:1856(identity)	sgd:S000002704|refseq:NP_010582.3|mint:Q06630|dip:DIP-5727N|ensemblfungi:YDR296W(gene)|ensemblfungi:YDR296W_mRNA(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0000150"(DNA strand exchange activity)|go:"GO:0003677"(DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0006310"(DNA recombination)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0032543"(mitochondrial translation)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0090297"(positive regulation of mitochondrial DNA replication)|interpro:IPR024629|rcsb pdb:3J6B|rcsb pdb:5MRC|rcsb pdb:5MRE|rcsb pdb:5MRF|sgd:YDR296W(identity)	-	-	crc64:F26903A4814091C4	figure legend:Table EV7|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2015/12/14	2016/02/04	rogid:2Vdc8oRnT4Mz/j+EXQXrL3AszOc9606	rogid:eA38S7UNOpP716XSQ0zzhYm2TqA559292	intact-crc:BF8379A03FAB5D11|rigid:KfACV2u1KAa7GX/3udfMqHYgtRY	false	renilla luciferase protein tag:n-n	tandem tag:n-n	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q07732	uniprotkb:Q96IK5	intact:EBI-33406|ensemblfungi:YDL239C|uniprotkb:D6VRB7	intact:EBI-2548508|ensembl:ENSP00000282570|uniprotkb:Q9H826|uniprotkb:Q9H8V7|uniprotkb:Q9H927	psi-mi:ady3_yeast(display_long)|uniprotkb:YDL239C(locus name)|uniprotkb:ADY3(gene name)|psi-mi:ADY3(display_short)	psi-mi:gmcl1_human(display_long)|uniprotkb:GMCL1(gene name)|psi-mi:GMCL1(display_short)|uniprotkb:GCL(gene name synonym)|uniprotkb:BTBD13(gene name synonym)|uniprotkb:SPATA29(gene name synonym)|uniprotkb:Spermatogenesis-associated protein 29(gene name synonym)	psi-mi:"MI:0729"(luminescence based mammalian interactome mapping)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11548641|imex:IM-24995-2764	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010042.2|sgd:S000002398|ensemblfungi:YDL239C(gene)|ensemblfungi:YDL239C_mRNA(transcript)|go:"GO:0000001"(mitochondrion inheritance)|go:"GO:0005628"(prospore membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0030435"(sporulation resulting in formation of a cellular spore)|go:"GO:0030476"(ascospore wall assembly)|go:"GO:0032120"(ascospore-type prospore membrane formation)|go:"GO:0051301"(cell division)|go:"GO:0070056"(prospore membrane leading edge)|interpro:IPR021750|mint:Q07732|dip:DIP-1811N|sgd:YDL239C(identity)	ensembl:ENSG00000087338(gene)|ensembl:ENST00000282570(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0007281"(germ cell development)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016363"(nuclear matrix)|go:"GO:0042802"(identical protein binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR043380|refseq:NP_848526.1|entrezgene/locuslink:64395(identity)	-	crc64:46F17474F30FD3D9	-	figure legend:Table EV7|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2015/12/14	2016/02/04	rogid:Cmac2NLDdbBzVKnJfFricfeeX24559292	rogid:ED8yqySVu7BWxpw3DUSNBZSQWrk9606	intact-crc:E0C25425CC851EF8|rigid:tPzkqD4O/YtqXvlondCuqaUq5Yk	false	tandem tag:n-n	renilla luciferase protein tag:n-n	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9UH77	uniprotkb:Q08273	intact:EBI-8524663|uniprotkb:Q9ULU0|uniprotkb:B2RBK7|intact:UNK-6172988|uniprotkb:Q9UH76|uniprotkb:Q9UH75|uniprotkb:Q9Y6V6|ensembl:ENSP00000312397	intact:EBI-31686|uniprotkb:D6W1T5|ensemblfungi:YOL133W	psi-mi:klhl3_human(display_long)|uniprotkb:KLHL3(gene name)|psi-mi:KLHL3(display_short)|uniprotkb:KIAA1129(gene name synonym)	psi-mi:rbx1_yeast(display_long)|uniprotkb:E3 ubiquitin-protein ligase complex SCF subunit HRT1(gene name synonym)|uniprotkb:High level expression reduces Ty3 transposition protein 1(gene name synonym)|uniprotkb:HRT1(gene name)|psi-mi:HRT1(display_short)|uniprotkb:RBX1(gene name synonym)|uniprotkb:ROC1(gene name synonym)|uniprotkb:Regulator of cullins protein 1(gene name synonym)|uniprotkb:YOL133W(locus name)	psi-mi:"MI:0729"(luminescence based mammalian interactome mapping)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11548654|imex:IM-24995-2765	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_059111.2|refseq:NP_001244124.1|refseq:NP_001244123.1|ensembl:ENSG00000146021(gene)|ensembl:ENST00000309755(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0050801"(ion homeostasis)|go:"GO:0061912"(selective autophagy)|go:"GO:0070294"(renal sodium ion absorption)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0072156"(distal tubule morphogenesis)|go:"GO:0097602"(cullin family protein binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR017096(Kelch-like protein, gigaxonin)|interpro:IPR030578|rcsb pdb:4CH9|rcsb pdb:4HXI|rcsb pdb:5NKP|reactome:R-HSA-8951664|reactome:R-HSA-983168|entrezgene/locuslink:26249(identity)	refseq:NP_014508.1|sgd:S000005493|dip:DIP-1373N|mint:Q08273|ensemblfungi:YOL133W(gene)|ensemblfungi:YOL133W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0035361"(Cul8-RING ubiquitin ligase complex)|go:"GO:0051301"(cell division)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097602"(cullin family protein binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR024766|reactome:R-SCE-5696395|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-68949|reactome:R-SCE-8854050|reactome:R-SCE-8951664|reactome:R-SCE-983168|sgd:YOL133W(identity)	-	comment:mint|comment:homomint|function:Probable substrate-specific adapter of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins	crc64:A9C3193E48CAF881	figure legend:Table EV7|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2015/12/14	2016/02/04	rogid:6iZNPY/wNDhLlUWeFLl0FyqtFXM9606	rogid:7LBUfvb6zpWuPkbMDrEAnrMuJj8559292	intact-crc:87AB7FA52EBFC22A|rigid:stfWFAyIC45liOFdXxuWXPy9o8Y	false	renilla luciferase protein tag:n-n|sufficient binding region:1-301	tandem tag:n-n	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q15911-2	uniprotkb:Q12318	intact:EBI-10237226|ensembl:ENSP00000438926	intact:EBI-37340|uniprotkb:D6VZ12|ensemblfungi:YLR376C	psi-mi:q15911-2(display_long)|uniprotkb:ZFHX3(gene name)|psi-mi:ZFHX3(display_short)|uniprotkb:AT motif-binding factor 1(gene name synonym)|uniprotkb:AT-binding transcription factor 1(gene name synonym)|uniprotkb:ATBF1(gene name synonym)|uniprotkb:Alpha-fetoprotein enhancer-binding protein(gene name synonym)|uniprotkb:Zinc finger homeodomain protein 3(gene name synonym)|uniprotkb:C16orf47(gene name synonym)	psi-mi:psy3_yeast(display_long)|uniprotkb:PSY3(gene name)|psi-mi:PSY3(display_short)|uniprotkb:L8039.17(orf name)|uniprotkb:YLR376C(locus name)	psi-mi:"MI:0729"(luminescence based mammalian interactome mapping)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11548669|imex:IM-24995-2766	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-2849611(isoform-parent)|uniprotkb:Q15911-2(isoform-parent)|ensembl:ENST00000397992(transcript)|ensembl:ENSG00000140836(gene)|entrezgene/locuslink:463(identity)	sgd:S000004368|refseq:NP_013480.1|dip:DIP-1903N|ensemblfungi:YLR376C(gene)|ensemblfungi:YLR376C_mRNA(transcript)|go:"GO:0000725"(recombinational repair)|go:"GO:0000730"(DNA recombinase assembly)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0035861"(site of double-strand break)|go:"GO:0070987"(error-free translesion synthesis)|go:"GO:0097196"(Shu complex)|interpro:IPR027417|interpro:IPR031779|rcsb pdb:3VU9|rcsb pdb:4DT1|rcsb pdb:4EQ6|rcsb pdb:5XYN|sgd:YLR376C(identity)	-	-	crc64:B652FD8113EB4C12	figure legend:Table EV7|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2015/12/14	2016/02/04	rogid:2SwbWXRFfxKEHEbo/SlMGw8/hPU9606	rogid:SlNKYcljv2UVV8YxX5/kVQJV/rU559292	intact-crc:BE981D4A0D18285F|rigid:lt0Ppo9sfiGTtecbUmGmPV8ZC3U	false	sufficient binding region:1-886|renilla luciferase protein tag:n-n	tandem tag:n-n	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8N9N5-2	uniprotkb:Q12329	intact:EBI-11524452|ensembl:ENSP00000347125	intact:EBI-8571|uniprotkb:D6VSF3|ensemblfungi:YDR171W	psi-mi:q8n9n5-2(display_long)|uniprotkb:BANP(gene name)|psi-mi:BANP(display_short)|uniprotkb:BEN domain-containing protein 1(gene name synonym)|uniprotkb:BEND1(gene name synonym)|uniprotkb:Btg3-associated nuclear protein(gene name synonym)|uniprotkb:SMAR1(gene name synonym)|uniprotkb:Scaffold/matrix-associated region-1-binding protein(gene name synonym)	psi-mi:hsp42_yeast(display_long)|uniprotkb:HSP42(gene name)|psi-mi:HSP42(display_short)|uniprotkb:YDR171W(locus name)|uniprotkb:YD9395.04(orf name)|uniprotkb:42 kDa heat shock protein(gene name synonym)	psi-mi:"MI:0729"(luminescence based mammalian interactome mapping)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11548684|imex:IM-24995-2767	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000172530(gene)|ensembl:ENST00000355022(transcript)|intact:EBI-744695(isoform-parent)|uniprotkb:Q8N9N5-2(isoform-parent)|entrezgene/locuslink:54971(identity)	refseq:NP_010456.1|sgd:S000002578|mint:Q12329|dip:DIP-2515N|ensemblfungi:YDR171W(gene)|ensemblfungi:YDR171W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0009408"(response to heat)|go:"GO:0009651"(response to salt stress)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043621"(protein self-association)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0140311"(protein sequestering activity)|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR031107|sgd:YDR171W(identity)	-	-	crc64:DF353A76493E3CE6	figure legend:Table EV7|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2015/12/14	2016/02/04	rogid:ESe6iCAhvq+i57fQHz3rGyg6UOo9606	rogid:izvrv04fA3zcBqTeUeHD/erKGf4559292	intact-crc:1D9DB6AD9C02CAAB|rigid:qfKsJw/YTjkS/vwRcAEuCJNyM8o	false	renilla luciferase protein tag:n-n	tandem tag:n-n	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q5T124-6	uniprotkb:Q12329	intact:EBI-11524408	intact:EBI-8571|uniprotkb:D6VSF3|ensemblfungi:YDR171W	psi-mi:q5t124-6(display_long)|uniprotkb:UBXN11(gene name)|psi-mi:UBXN11(display_short)|uniprotkb:Colorectal tumor-associated antigen COA-1(gene name synonym)|uniprotkb:SOC(gene name synonym)|uniprotkb:Socius(gene name synonym)|uniprotkb:UBX domain-containing protein 5(gene name synonym)|uniprotkb:UBXD5(gene name synonym)|uniprotkb:PP2243(orf name)	psi-mi:hsp42_yeast(display_long)|uniprotkb:HSP42(gene name)|psi-mi:HSP42(display_short)|uniprotkb:YDR171W(locus name)|uniprotkb:YD9395.04(orf name)|uniprotkb:42 kDa heat shock protein(gene name synonym)	psi-mi:"MI:0729"(luminescence based mammalian interactome mapping)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11548723|imex:IM-24995-2770	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-746004(isoform-parent)|uniprotkb:Q5T124-6(isoform-parent)|entrezgene/locuslink:91544(identity)	refseq:NP_010456.1|sgd:S000002578|mint:Q12329|dip:DIP-2515N|ensemblfungi:YDR171W(gene)|ensemblfungi:YDR171W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0009408"(response to heat)|go:"GO:0009651"(response to salt stress)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043621"(protein self-association)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0140311"(protein sequestering activity)|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR031107|sgd:YDR171W(identity)	-	-	crc64:DF353A76493E3CE6	figure legend:Table EV7|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2015/12/14	2016/02/09	rogid:1YSjG/p2ihcjl4P8KdPCaX2HxiY9606	rogid:izvrv04fA3zcBqTeUeHD/erKGf4559292	intact-crc:90648A2E1E44A9C4|rigid:6C7uPE50u2e0rlNYgtHYRIEau/I	false	tandem tag:n-n	renilla luciferase protein tag:n-n	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P27476	uniprotkb:Q14141-4	intact:EBI-12274|ensemblfungi:YGR159C|uniprotkb:D6VUT9	intact:EBI-11524882|ensembl:ENSP00000346169	psi-mi:nsr1_yeast(display_long)|uniprotkb:NSR1(gene name)|psi-mi:NSR1(display_short)|uniprotkb:YGR159C(locus name)|uniprotkb:G7001(orf name)|uniprotkb:p67(gene name synonym)	psi-mi:q14141-4(display_long)|uniprotkb:SEPTIN6(gene name)|psi-mi:SEPTIN6(display_short)|uniprotkb:KIAA0128(gene name synonym)|uniprotkb:SEP2(gene name synonym)|uniprotkb:SEPT6(gene name synonym)	psi-mi:"MI:0729"(luminescence based mammalian interactome mapping)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11548710|imex:IM-24995-2769	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YGR159C(gene)|ensemblfungi:YGR159C_mRNA(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006364"(rRNA processing)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0043047"(single-stranded telomeric DNA binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034276|interpro:IPR035979|interpro:IPR034272|refseq:NP_011675.1|sgd:S000003391|mint:P27476|dip:DIP-5537N|sgd:YGR159C(identity)	ensembl:ENSG00000125354(gene)|ensembl:ENST00000354228(transcript)|intact:EBI-745901(isoform-parent)|entrezgene/locuslink:23157(identity)	-	crc64:90DEEE7BBC20BC0C	-	figure legend:Table EV7|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2015/12/14	2016/02/09	rogid:q0/AgJC55iTpn/5kCsxal2kQ7Ls559292	rogid:QfLbdoBUG/Q5IYeoadJOtAK+kj49606	intact-crc:3FE117FD70D463BA|rigid:XNO6KTqFQk4W9Ap+A+2Gcj+WX/A	false	renilla luciferase protein tag:n-n	tandem tag:n-n	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q13422-7	uniprotkb:Q06671	intact:EBI-11522367|ensembl:ENSP00000352123|ensembl:ENSP00000413025	intact:EBI-3685534|uniprotkb:D6VZ66|ensemblfungi:YLR431C	psi-mi:q13422-7(display_long)|uniprotkb:IKZF1(gene name)|psi-mi:IKZF1(display_short)|uniprotkb:IK1(gene name synonym)|uniprotkb:IKAROS(gene name synonym)|uniprotkb:Ikaros family zinc finger protein 1(gene name synonym)|uniprotkb:LYF1(gene name synonym)|uniprotkb:Lymphoid transcription factor LyF-1(gene name synonym)|uniprotkb:ZNFN1A1(gene name synonym)	psi-mi:atg23_yeast(display_long)|uniprotkb:ATG23(gene name)|psi-mi:ATG23(display_short)|uniprotkb:CVT23(gene name synonym)|uniprotkb:Cytoplasm to vacuole targeting protein 23(gene name synonym)|uniprotkb:YLR431C(locus name)	psi-mi:"MI:0729"(luminescence based mammalian interactome mapping)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11548697|imex:IM-24995-2768	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-745305(isoform-parent)|ensembl:ENSG00000185811(gene)|ensembl:ENST00000359197(transcript)|ensembl:ENST00000439701(transcript)|uniprotkb:Q13422-7(isoform-parent)|entrezgene/locuslink:10320(identity)	sgd:S000004423|refseq:NP_013535.1|ensemblfungi:YLR431C(gene)|ensemblfungi:YLR431C_mRNA(transcript)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0044805"(late nucleophagy)|sgd:YLR431C(identity)	-	-	-	figure legend:Table EV7|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2015/12/14	2016/02/09	rogid:ou/ovXYoMneBNVp4pj38VxenfyY9606	rogid:6KEtQbyIfmG3hnxsqr3+hHGrEa0559292	intact-crc:3A9153794F6077DB|rigid:g+xJ5gDXbhYnOsvVB5FAHzXHfAk	false	tandem tag:n-n	renilla luciferase protein tag:n-n	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q7L190	uniprotkb:Q12161	intact:EBI-710457|intact:EBI-28975079|ensembl:ENSP00000335306|uniprotkb:Q9H9N5|uniprotkb:Q9NVI6|uniprotkb:A8K4M7	intact:EBI-34372|uniprotkb:D6W213|ensemblfungi:YOL054W	psi-mi:dppa4_human(display_long)|uniprotkb:DPPA4(gene name)|psi-mi:DPPA4(display_short)	psi-mi:psh1_yeast(display_long)|uniprotkb:PSH1(gene name)|psi-mi:PSH1(display_short)|uniprotkb:POB3/SPT16 histone-associated protein 1(gene name synonym)|uniprotkb:O1263(orf name)|uniprotkb:YOL054W(locus name)	psi-mi:"MI:0729"(luminescence based mammalian interactome mapping)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11548736|imex:IM-24995-2771	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060659.3|mint:Q7L190|reactome:R-HSA-2892247|ensembl:ENSG00000121570(gene)|ensembl:ENST00000335658(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0048731"(system development)|go:"GO:0060484"(lung-associated mesenchyme development)|interpro:IPR025891|interpro:IPR025892|interpro:IPR039590|interpro:IPR039836|ensembl:ENSP00000335306|entrezgene/locuslink:55211(identity)	refseq:NP_014587.1|sgd:S000005415|mint:Q12161|dip:DIP-6481N|ensemblfungi:YOL054W(gene)|ensemblfungi:YOL054W_mRNA(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|sgd:YOL054W(identity)	-	-	crc64:CE0ECBCB6D465554	figure legend:Table EV7|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2015/12/14	2016/02/09	rogid:WKqQ0ipAAfKsDRuXJhtTWJcROdc9606	rogid:AvPMRd/GjfaTyQjEfMPhBVcvOs4559292	intact-crc:B8FEA87F07FF93D0|rigid:ntfXmWM1RHuN/MhAxByifxCsJw4	false	tandem tag:n-n|sufficient binding region:11-304	renilla luciferase protein tag:n-n	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8N684-3	uniprotkb:P20053	intact:EBI-11523759|ensembl:ENSP00000345412	intact:EBI-219|uniprotkb:D6W4H8|ensemblfungi:YPR178W	psi-mi:q8n684-3(display_long)|uniprotkb:Cleavage factor Im complex 59 kDa subunit(gene name synonym)|uniprotkb:CPSF7(gene name)|psi-mi:CPSF7(display_short)|uniprotkb:Cleavage and polyadenylation specificity factor 59 kDa subunit(gene name synonym)|uniprotkb:Pre-mRNA cleavage factor Im 59 kDa subunit(gene name synonym)	psi-mi:prp4_yeast(display_long)|uniprotkb:PRP4(gene name)|psi-mi:PRP4(display_short)|uniprotkb:RNA4(gene name synonym)|uniprotkb:YPR178W(locus name)|uniprotkb:P9705.6(orf name)|uniprotkb:Pre-mRNA-processing protein 4(gene name synonym)	psi-mi:"MI:0729"(luminescence based mammalian interactome mapping)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11548766|imex:IM-24995-2773	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-746909(isoform-parent)|ensembl:ENSG00000149532(gene)|ensembl:ENST00000340437(transcript)|uniprotkb:Q8N684-3(isoform-parent)|entrezgene/locuslink:79869(identity)	refseq:NP_015504.1|sgd:S000006382|mint:P20053|dip:DIP-2607N|ensemblfungi:YPR178W(gene)|ensemblfungi:YPR178W_mRNA(transcript)|go:"GO:0000393"(spliceosomal conformational changes to generate catalytic conformation)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0030621"(U4 snRNA binding)|go:"GO:0034247"(snoRNA splicing)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR014906("Pre-mRNA processing factor 4 (PRP4) like")|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|rcsb pdb:3JCM|rcsb pdb:5GAN|rcsb pdb:5GAP|rcsb pdb:5NRL|rcsb pdb:5ZWM|rcsb pdb:5ZWO|sgd:YPR178W(identity)	-	-	crc64:7CCCA3A92AC0CE78	figure legend:Table EV7|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2015/12/14	2016/02/09	rogid:hnk6o9HBKsdIRWKRuEdjdByVKxM9606	rogid:vvz5G0rqqyrugTvAPelDKit9FpQ559292	intact-crc:3310F7385D0CEB82|rigid:5QtYmVwYNwdsIJirXMxzEGeQUeU	false	tandem tag:n-n|sufficient binding region:44-514	renilla luciferase protein tag:n-n	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96BA8	uniprotkb:P40107	intact:EBI-6942903|ensembl:ENSP00000481956|intact:MINT-268046|intact:MINT-8162577|uniprotkb:Q8N2D5|uniprotkb:Q96CP0	intact:EBI-7764|uniprotkb:D6VVB0|ensemblfungi:YGL225W	psi-mi:cr3l1_human(display_long)|uniprotkb:CREB3L1(gene name)|psi-mi:CREB3L1(display_short)|uniprotkb:OASIS(gene name synonym)|uniprotkb:PSEC0238(orf name)|uniprotkb:Old astrocyte specifically-induced substance(gene name synonym)	psi-mi:gmt1_yeast(display_long)|uniprotkb:VRG4(gene name)|psi-mi:VRG4(display_short)|uniprotkb:MCD3(gene name synonym)|uniprotkb:VAN2(gene name synonym)|uniprotkb:GOG5(gene name synonym)|uniprotkb:LDB3(gene name synonym)|uniprotkb:Vanadate resistance glycosylation protein 4(gene name synonym)|uniprotkb:Low dye-binding protein 3(gene name synonym)|uniprotkb:Morphogenesis checkpoint-dependent protein 3(gene name synonym)|uniprotkb:VIG4(gene name synonym)|uniprotkb:YGL225W(locus name)	psi-mi:"MI:0729"(luminescence based mammalian interactome mapping)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11548781|imex:IM-24995-2774	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157613(gene)|ensembl:ENST00000621158(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0070278"(extracellular matrix constituent secretion)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029805|mint:Q96BA8|reactome:R-HSA-8874211|refseq:NP_443086.1|entrezgene/locuslink:90993(identity)	refseq:NP_011290.1|sgd:S000003193|dip:DIP-5108N|ensemblfungi:YGL225W(gene)|ensemblfungi:YGL225W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005458"(GDP-mannose transmembrane transporter activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0008643"(carbohydrate transport)|go:"GO:0015297"(antiporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:1990570"(GDP-mannose transmembrane transport)|interpro:IPR038736|rcsb pdb:5OGE|rcsb pdb:5OGK|rcsb pdb:6QSK|sgd:YGL225W(identity)	-	comment:mint|function:"Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE"	-	figure legend:Table EV7|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2015/12/14	2016/02/09	rogid:sMWUFmBeBBCO+T0Y2CuB/un1lBg9606	rogid:ZYzY/DU+8rq6BJZz/a4LlZa8I4w559292	intact-crc:EFD857FE2E7F51FC|rigid:ZzXUPAYRI5Hrp+MRYH8Rif5ZS9A	false	tandem tag:n-n	renilla luciferase protein tag:n-n	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P25637	uniprotkb:Q96HT8	intact:EBI-21951|uniprotkb:D6VR64|ensemblfungi:YCR059C	intact:EBI-748896|uniprotkb:Q6NXT8|uniprotkb:Q9P0J5|uniprotkb:B2R6R0|ensembl:ENSP00000318154	psi-mi:yih1_yeast(display_long)|uniprotkb:YCR59C(orf name)|uniprotkb:YCR059C(locus name)|uniprotkb:YIH1(gene name)|psi-mi:YIH1(display_short)	psi-mi:mr1l1_human(display_long)|uniprotkb:PP784(orf name)|uniprotkb:MRFAP1L1(gene name)|psi-mi:MRFAP1L1(display_short)	psi-mi:"MI:0729"(luminescence based mammalian interactome mapping)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11548794|imex:IM-24995-2775	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009985.1|sgd:S000000655|mint:P25637|dip:DIP-1846N|ensemblfungi:YCR059C(gene)|ensemblfungi:YCR059C_mRNA(transcript)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0003785"(actin monomer binding)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0033673"(negative regulation of kinase activity)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0043022"(ribosome binding)|go:"GO:0140469"(GCN2-mediated signaling)|go:"GO:1905538"(polysome binding)|interpro:IPR001498(Protein of unknown function UPF0029, N-terminal)|interpro:IPR006575(RWD)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR020568|interpro:IPR020569|interpro:IPR023582|interpro:IPR036956|rcsb pdb:6BQI|rcsb pdb:6U1L|rcsb pdb:6U1O|sgd:YCR059C(identity)	refseq:NP_982287.1|refseq:XP_005247989.1|ensembl:ENSG00000178988(gene)|ensembl:ENST00000320848(transcript)|go:"GO:0042802"(identical protein binding)|interpro:IPR029254|mint:Q96HT8|dip:DIP-29019N|entrezgene/locuslink:114932(identity)	-	-	caution:This sequence has been withdrawn from Uniprot.|crc64:6C914B0B4BEECAE5	figure legend:Table EV7|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2015/12/14	2016/02/09	rogid:aAbGir3o4M0LUpwOv6YBC25KpQQ559292	rogid:hb4enqSS7DeieOByDoLDkXkSlIk9606	intact-crc:7B536878CC12EA86|rigid:DmLeJugk9z8HWbVTC4xBweyUnV0	false	renilla luciferase protein tag:n-n	tandem tag:n-n	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96LP2	uniprotkb:P38271	intact:EBI-10290827|ensembl:ENSP00000283357	intact:EBI-12563|uniprotkb:D6VQC6|ensemblfungi:YBR129C	psi-mi:fa81b_human(display_long)|uniprotkb:FAM81B(gene name)|psi-mi:FAM81B(display_short)	psi-mi:opy1_yeast(display_long)|uniprotkb:OPY1(gene name)|psi-mi:OPY1(display_short)|uniprotkb:YBR129C(locus name)|uniprotkb:YBR1004(orf name)|uniprotkb:Overproduction-induced pheromone-resistant yeast protein 1(gene name synonym)	psi-mi:"MI:0729"(luminescence based mammalian interactome mapping)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11548807|imex:IM-24995-2776	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_689761.2|ensembl:ENSG00000153347(gene)|ensembl:ENST00000283357(transcript)|go:"GO:0005634"(nucleus)|interpro:IPR029619|interpro:IPR029620|entrezgene/locuslink:153643(identity)	ensemblfungi:YBR129C(gene)|ensemblfungi:YBR129C_mRNA(transcript)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:1902647"(negative regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016609(Uncharacterised conserved protein UCP013217, Opy1p)|refseq:NP_009687.1|sgd:S000000333|dip:DIP-4768N|sgd:YBR129C(identity)	-	-	crc64:BB4BECCA7C67A5D9	figure legend:Table EV7|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2015/12/14	2020/03/03	rogid:V9VtnYUHk767ZnWUCuuxiUfJF+09606	rogid:97mFgMzTXaBI8NoMtAweXDE8i3s559292	intact-crc:49ABF82EC8DEF100|rigid:n0Yhpn+39w5sOOefaMKMeX8eiVc	false	tandem tag:n-n|sufficient binding region:39-452	renilla luciferase protein tag:n-n	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q7Z6G3-2	uniprotkb:O13539	intact:EBI-10172876|ensembl:ENSP00000457354|intact:EBI-14062040	intact:EBI-30898|uniprotkb:D3DLB6|ensemblfungi:YHR167W	psi-mi:q7z6g3-2(display_long)|uniprotkb:EFCBP2(gene name synonym)|uniprotkb:Neuronal calcium-binding protein 2(gene name synonym)|uniprotkb:Synaptotagmin-interacting protein 2(gene name synonym)|uniprotkb:NECAB2(gene name)|psi-mi:NECAB2(display_short)	psi-mi:thp2_yeast(display_long)|uniprotkb:THP2(gene name)|psi-mi:THP2(display_short)|uniprotkb:YHR167W(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11548832|imex:IM-24995-2779	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000103154(gene)|ensembl:ENST00000565691(transcript)|uniprotkb:Q7Z6G3-2(isoform-parent)|intact:EBI-950070(isoform-parent)	refseq:NP_012037.1|sgd:S000001210|dip:DIP-4246N|mint:O13539|ensemblfungi:YHR167W(gene)|ensemblfungi:YHR167W_mRNA(transcript)|go:"GO:0000445"(THO complex part of transcription export complex)|go:"GO:0000446"(nucleoplasmic THO complex)|go:"GO:0000723"(telomere maintenance)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0006310"(DNA recombination)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0034063"(stress granule assembly)|interpro:IPR018557|rcsb pdb:7APX|rcsb pdb:7LUV	-	-	crc64:16EFA6F464507C57	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:4S7oIx6h+mKzV3EPxqcfMNqaNko9606	rogid:SaTSL6jLwX1hTVCqvU8ZNR96r8U559292	intact-crc:E36DD47960922E25|rigid:V2uDZVRRDFQLR0A82FXu/kkIes8	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q08379	intact:EBI-11522208	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	-	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:ylr445w(display_short)|psi-mi:EBI-11522208(display_long)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11548824|imex:IM-24995-2777	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N	-	-	-	no-uniprot-update:	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2017/05/26	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	rogid:kUe7etYjGLH6i6KZ5N2LXUnjAf04932	intact-crc:087AEEAE2AA8AE0C|rigid:KkBN0sQ8Zc2sadqGnr4/J3iuD1A	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
intact:EBI-11522220	uniprotkb:J3KPQ4	-	intact:EBI-11522225	psi-mi:lsb3(display_short)|psi-mi:EBI-11522220(display_long)	psi-mi:j3kpq4_human(display_long)|uniprotkb:hCG_39668(orf name)|uniprotkb:ARHGAP9(gene name)|psi-mi:ARHGAP9(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11548828|imex:IM-24995-2778	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	-	interpro:IPR000198(RhoGAP)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035465|refseq:NP_001306779.1|go:"GO:0005096"(GTPase activator activity)|go:"GO:0007165"(signal transduction)|interpro:IPR036020|interpro:IPR036028	-	no-uniprot-update:	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:lsGJZWImagMoiiCZztCcxCn2LlU4932	rogid:H9MJrfHtg/AF6G6rqm+nDFz32lo9606	intact-crc:B537B86BC1D91E37|rigid:RtOoXkTmAlkeS6I+dTMX6DKn6hY	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
intact:EBI-11522220	uniprotkb:O15156-2	-	intact:EBI-11522250|ensembl:ENSP00000406286	psi-mi:lsb3(display_short)|psi-mi:EBI-11522220(display_long)	psi-mi:o15156-2(display_long)|uniprotkb:ZBTB7B(gene name)|psi-mi:ZBTB7B(display_short)|uniprotkb:Krueppel-related zinc finger protein cKrox(gene name synonym)|uniprotkb:T-helper-inducing POZ/Krueppel-like factor(gene name synonym)|uniprotkb:ZBTB15(gene name synonym)|uniprotkb:ZFP67(gene name synonym)|uniprotkb:ZNF857B(gene name synonym)|uniprotkb:Zinc finger and BTB domain-containing protein 15(gene name synonym)|uniprotkb:Zinc finger protein 67 homolog(gene name synonym)|uniprotkb:Zinc finger protein 857B(gene name synonym)|uniprotkb:Zinc finger protein Th-POK(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11548848|imex:IM-24995-2783	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	-	intact:EBI-740434(isoform-parent)|ensembl:ENSG00000160685(gene)|ensembl:ENST00000417934(transcript)|uniprotkb:O15156-2(isoform-parent)	-	no-uniprot-update:	isoform-comment:No experimental confirmation available.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:lsGJZWImagMoiiCZztCcxCn2LlU4932	rogid:41NEFYyprTXI+fOHVFh78TPKF289606	intact-crc:17136EBE8F246BA8|rigid:8Xzv2aOPdULdtJOvuLu4NO8LkC8	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O14641	intact:EBI-11522238	intact:EBI-740850|ensembl:ENSP00000005340|uniprotkb:Q53XM0|uniprotkb:D3DTN3	-	psi-mi:dvl2_human(display_long)|uniprotkb:DSH homolog 2(gene name synonym)|uniprotkb:DVL2(gene name)|psi-mi:DVL2(display_short)	psi-mi:cyc2(display_short)|psi-mi:EBI-11522238(display_long)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11548836|imex:IM-24995-2780	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004413.1|ensembl:ENSG00000004975(gene)|ensembl:ENST00000005340(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005109"(frizzled binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0007507"(heart development)|go:"GO:0016235"(aggresome)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044340"(canonical Wnt signaling pathway involved in regulation of cell proliferation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0150012"(positive regulation of neuron projection arborization)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008341(Dishevelled-2 region)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:O14641|rcsb pdb:2REY|rcsb pdb:3CBX|rcsb pdb:3CBY|rcsb pdb:3CBZ|rcsb pdb:3CC0|rcsb pdb:4WIP|rcsb pdb:5LNP|rcsb pdb:5SUY|rcsb pdb:5SUZ|rcsb pdb:6IW3|rcsb pdb:6JCK|reactome:R-HSA-201681|reactome:R-HSA-201688|reactome:R-HSA-2028269|reactome:R-HSA-4086400|reactome:R-HSA-4608870|reactome:R-HSA-4641258|reactome:R-HSA-4641262|reactome:R-HSA-5099900|reactome:R-HSA-5368598|reactome:R-HSA-5663220|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9673324|ensembl:ENSP00000005340|dip:DIP-34433N	-	-	-	no-uniprot-update:	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:2Vdc8oRnT4Mz/j+EXQXrL3AszOc9606	rogid:5RstlUmv8fpj9QSGrNaQaZc2OUU4932	intact-crc:85A0EA2CDB82AA57|rigid:VJEDE9PWZ37MtC3IhzljtXXrmE0	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O13566	uniprotkb:O14964	intact:EBI-29708|ensemblfungi:YPR123C	intact:EBI-740220|uniprotkb:Q9NR36|ensembl:ENSP00000331201|ensembl:ENSP00000504106	psi-mi:yp123_yeast(display_long)|uniprotkb:P9642.4B(orf name)|uniprotkb:YPR123C(locus name)	psi-mi:hgs_human(display_long)|uniprotkb:Protein pp110(gene name synonym)|uniprotkb:Hrs(gene name synonym)|uniprotkb:HGS(gene name)|psi-mi:HGS(display_short)|uniprotkb:HRS(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11548840|imex:IM-24995-2781	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000006327|dip:DIP-3811N|ensemblfungi:YPR123C(gene)|ensemblfungi:YPR123C_mRNA(transcript)|go:"GO:0016021"(integral component of membrane)	refseq:NP_004703.1|dip:DIP-29050N|ensembl:ENSG00000185359(gene)|ensembl:ENST00000329138(transcript)|ensembl:ENST00000676546(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0007165"(signal transduction)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010324"(membrane invagination)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010642"(negative regulation of platelet-derived growth factor receptor signaling pathway)|go:"GO:0016197"(endosomal transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032585"(multivesicular body membrane)|go:"GO:0033565"(ESCRT-0 complex)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043405"(regulation of MAP kinase activity)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072657"(protein localization to membrane)|go:"GO:0097013"(phagocytic vesicle lumen)|go:"GO:1903543"(positive regulation of exosomal secretion)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR002014(VHS)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017073(Ubiquitin binding protein, Hrs/VPS27)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR024641|mint:O14964|rcsb pdb:2D3G|rcsb pdb:3F1I|rcsb pdb:3OBQ|rcsb pdb:3ZYQ|rcsb pdb:4AVX|reactome:R-HSA-182971|reactome:R-HSA-432720|reactome:R-HSA-5689880|reactome:R-HSA-6807004|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8875360|reactome:R-HSA-9013420|reactome:R-HSA-917729|reactome:R-HSA-9635644|reactome:R-HSA-9636383|reactome:R-HSA-9706019	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:tb84y2TgUcLXIj6zwqC/7T8QHKg559292	rogid:z/AnREuqEpyJ9/Zj6JFCJCJem1I9606	intact-crc:6648C1A85032B217|rigid:Rl06iksuRyNqdidnPspyEoRr7kI	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O14964	uniprotkb:O13539	intact:EBI-740220|uniprotkb:Q9NR36|ensembl:ENSP00000331201|ensembl:ENSP00000504106	intact:EBI-30898|uniprotkb:D3DLB6|ensemblfungi:YHR167W	psi-mi:hgs_human(display_long)|uniprotkb:Protein pp110(gene name synonym)|uniprotkb:Hrs(gene name synonym)|uniprotkb:HGS(gene name)|psi-mi:HGS(display_short)|uniprotkb:HRS(gene name synonym)	psi-mi:thp2_yeast(display_long)|uniprotkb:THP2(gene name)|psi-mi:THP2(display_short)|uniprotkb:YHR167W(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11548844|imex:IM-24995-2782	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004703.1|dip:DIP-29050N|ensembl:ENSG00000185359(gene)|ensembl:ENST00000329138(transcript)|ensembl:ENST00000676546(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0007165"(signal transduction)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010324"(membrane invagination)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010642"(negative regulation of platelet-derived growth factor receptor signaling pathway)|go:"GO:0016197"(endosomal transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032585"(multivesicular body membrane)|go:"GO:0033565"(ESCRT-0 complex)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043405"(regulation of MAP kinase activity)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072657"(protein localization to membrane)|go:"GO:0097013"(phagocytic vesicle lumen)|go:"GO:1903543"(positive regulation of exosomal secretion)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR002014(VHS)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017073(Ubiquitin binding protein, Hrs/VPS27)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR024641|mint:O14964|rcsb pdb:2D3G|rcsb pdb:3F1I|rcsb pdb:3OBQ|rcsb pdb:3ZYQ|rcsb pdb:4AVX|reactome:R-HSA-182971|reactome:R-HSA-432720|reactome:R-HSA-5689880|reactome:R-HSA-6807004|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8875360|reactome:R-HSA-9013420|reactome:R-HSA-917729|reactome:R-HSA-9635644|reactome:R-HSA-9636383|reactome:R-HSA-9706019	refseq:NP_012037.1|sgd:S000001210|dip:DIP-4246N|mint:O13539|ensemblfungi:YHR167W(gene)|ensemblfungi:YHR167W_mRNA(transcript)|go:"GO:0000445"(THO complex part of transcription export complex)|go:"GO:0000446"(nucleoplasmic THO complex)|go:"GO:0000723"(telomere maintenance)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0006310"(DNA recombination)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0034063"(stress granule assembly)|interpro:IPR018557|rcsb pdb:7APX|rcsb pdb:7LUV	-	-	crc64:16EFA6F464507C57	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:z/AnREuqEpyJ9/Zj6JFCJCJem1I9606	rogid:SaTSL6jLwX1hTVCqvU8ZNR96r8U559292	intact-crc:AAEEEC9DFFDF3E2F|rigid:UC+FrYLu9HP0ocapfmrftA9xbGU	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P50222	uniprotkb:P06782	intact:EBI-748397|uniprotkb:O75263|ensembl:ENSP00000262041|uniprotkb:Q9UPL6|uniprotkb:B2R8I7|intact:EBI-10172134|intact:EBI-11522964|intact:EBI-11750003|intact:EBI-12702266|uniprotkb:A4D127	intact:EBI-17516|uniprotkb:D6VTA0|ensemblfungi:YDR477W	psi-mi:meox2_human(display_long)|uniprotkb:Mesenchyme homeobox 2(gene name synonym)|uniprotkb:Growth arrest-specific homeobox(gene name synonym)|uniprotkb:MEOX2(gene name)|psi-mi:MEOX2(display_short)|uniprotkb:GAX(gene name synonym)|uniprotkb:MOX2(gene name synonym)	psi-mi:snf1_yeast(display_long)|uniprotkb:SNF1(gene name)|psi-mi:SNF1(display_short)|uniprotkb:CAT1(gene name synonym)|uniprotkb:CCR1(gene name synonym)|uniprotkb:GLC2(gene name synonym)|uniprotkb:PAS14(gene name synonym)|uniprotkb:Sucrose nonfermentating protein 1(gene name synonym)|uniprotkb:D8035.20(orf name)|uniprotkb:YDR477W(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11548868|imex:IM-24995-2788	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000106511(gene)|ensembl:ENST00000262041(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0001757"(somite specification)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007275"(multicellular organism development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008015"(blood circulation)|go:"GO:0016607"(nuclear speck)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060173"(limb development)|go:"GO:0061053"(somite development)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR042634|refseq:NP_005915.2	refseq:NP_010765.3|sgd:S000002885|ensemblfungi:YDR477W(gene)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0071940"(fungal-type cell wall assembly)|go:"GO:0090606"(single-species surface biofilm formation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900436"(positive regulation of filamentous growth of a population of unicellular organisms in response to starvation)|go:"GO:2000222"(positive regulation of pseudohyphal growth)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013896(Ubiquitin-associated region 2)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR028375|interpro:IPR032270|rcsb pdb:2FH9|rcsb pdb:2QLV|rcsb pdb:3DAE|rcsb pdb:3HYH|rcsb pdb:3MN3|rcsb pdb:3T4N|rcsb pdb:3TDH|rcsb pdb:3TE5|reactome:R-SCE-1632852|reactome:R-SCE-163680|reactome:R-SCE-200425|reactome:R-SCE-380972|ensemblfungi:YDR477W_mRNA(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000144"(cellular bud neck septin ring)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004679"(AMP-activated protein kinase activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005641"(nuclear envelope lumen)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0007155"(cell adhesion)|go:"GO:0016239"(positive regulation of macroautophagy)|dip:DIP-18N|mint:P06782	-	-	crc64:F5C63565C986C4E3	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2017/05/26	rogid:fMv0ruKikzQ3MC0PBvJ3pOAjW+U9606	rogid:O/SAW1kJE3fpoXPHGLG01i9RePs559292	intact-crc:085872AC18962DD2|rigid:PszU6JY+588CpoIjGSz9UPjgW0o	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O14641	uniprotkb:P05738	intact:EBI-740850|ensembl:ENSP00000005340|uniprotkb:Q53XM0|uniprotkb:D3DTN3	intact:EBI-15439|uniprotkb:D6VU02|ensemblfungi:YGL147C	psi-mi:dvl2_human(display_long)|uniprotkb:DSH homolog 2(gene name synonym)|uniprotkb:DVL2(gene name)|psi-mi:DVL2(display_short)	psi-mi:rl9a_yeast(display_long)|uniprotkb:RPL9A(gene name)|psi-mi:RPL9A(display_short)|uniprotkb:RPL9(gene name synonym)|uniprotkb:RPL8A(gene name synonym)|uniprotkb:L8(gene name synonym)|uniprotkb:YL11(gene name synonym)|uniprotkb:RP24(gene name synonym)|uniprotkb:YGL147C(locus name)|uniprotkb:Large ribosomal subunit protein uL6-A(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11548864|imex:IM-24995-2787	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004413.1|ensembl:ENSG00000004975(gene)|ensembl:ENST00000005340(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005109"(frizzled binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0007507"(heart development)|go:"GO:0016235"(aggresome)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044340"(canonical Wnt signaling pathway involved in regulation of cell proliferation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0150012"(positive regulation of neuron projection arborization)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008341(Dishevelled-2 region)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:O14641|rcsb pdb:2REY|rcsb pdb:3CBX|rcsb pdb:3CBY|rcsb pdb:3CBZ|rcsb pdb:3CC0|rcsb pdb:4WIP|rcsb pdb:5LNP|rcsb pdb:5SUY|rcsb pdb:5SUZ|rcsb pdb:6IW3|rcsb pdb:6JCK|reactome:R-HSA-201681|reactome:R-HSA-201688|reactome:R-HSA-2028269|reactome:R-HSA-4086400|reactome:R-HSA-4608870|reactome:R-HSA-4641258|reactome:R-HSA-4641262|reactome:R-HSA-5099900|reactome:R-HSA-5368598|reactome:R-HSA-5663220|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9673324|ensembl:ENSP00000005340|dip:DIP-34433N	sgd:S000003115|refseq:NP_011368.3|ensemblfungi:YGL147C(gene)|ensemblfungi:YGL147C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0019843"(rRNA binding)|go:"GO:0022625"(cytosolic large ribosomal subunit)|interpro:IPR000702(Ribosomal protein L6)|interpro:IPR002359(Ribosomal protein L6, conserved site-2)|interpro:IPR020040|interpro:IPR036789|rcsb pdb:1K5Y|rcsb pdb:3J16|rcsb pdb:3J6X|rcsb pdb:3J6Y|rcsb pdb:3J77|rcsb pdb:3J78|rcsb pdb:3JCT|rcsb pdb:4U3M|rcsb pdb:4U3N|rcsb pdb:4U3U|rcsb pdb:4U4N|rcsb pdb:4U4O|rcsb pdb:4U4Q|rcsb pdb:4U4R|rcsb pdb:4U4U|rcsb pdb:4U4Y|rcsb pdb:4U4Z|rcsb pdb:4U50|rcsb pdb:4U51|rcsb pdb:4U52|rcsb pdb:4U53|rcsb pdb:4U55|rcsb pdb:4U56|rcsb pdb:4U6F|rcsb pdb:4V4B|rcsb pdb:4V6I|rcsb pdb:4V7F|rcsb pdb:4V7R|rcsb pdb:4V88|rcsb pdb:4V8T|rcsb pdb:4V8Y|rcsb pdb:7NRD|rcsb pdb:4V8Z|rcsb pdb:4V91|rcsb pdb:5APN|rcsb pdb:5APO|rcsb pdb:5DAT|rcsb pdb:5DC3|rcsb pdb:5DGE|rcsb pdb:5DGF|rcsb pdb:5DGV|rcsb pdb:5FCI|rcsb pdb:5FCJ|rcsb pdb:5FL8|rcsb pdb:5GAK|rcsb pdb:5H4P|rcsb pdb:5I4L|rcsb pdb:5JCS|rcsb pdb:5JUO|rcsb pdb:5JUP|rcsb pdb:5JUS|rcsb pdb:5JUT|rcsb pdb:5JUU|rcsb pdb:5LYB|rcsb pdb:5M1J|rcsb pdb:5MC6|rcsb pdb:5MEI|rcsb pdb:5NDG|rcsb pdb:5NDV|rcsb pdb:5NDW|rcsb pdb:5OBM|rcsb pdb:5ON6|rcsb pdb:5T62|rcsb pdb:5T6R|rcsb pdb:5TBW|rcsb pdb:5TGA|rcsb pdb:5TGM|rcsb pdb:5Z3G|rcsb pdb:6ELZ|rcsb pdb:6EM1|rcsb pdb:6EM5|rcsb pdb:6FT6|rcsb pdb:6GQ1|rcsb pdb:6GQB|rcsb pdb:6GQV|rcsb pdb:6HD7|rcsb pdb:6HHQ|rcsb pdb:6I7O|rcsb pdb:6M62|rcsb pdb:6N8J|rcsb pdb:6N8K|rcsb pdb:6N8L|rcsb pdb:6N8M|rcsb pdb:6N8N|rcsb pdb:6N8O|rcsb pdb:6OIG|rcsb pdb:6Q8Y|rcsb pdb:6QIK|rcsb pdb:6QT0|rcsb pdb:6QTZ|rcsb pdb:6R84|rcsb pdb:6R86|rcsb pdb:6R87|rcsb pdb:6RI5|rcsb pdb:6RZZ|rcsb pdb:6S05|rcsb pdb:6S47|rcsb pdb:6SNT|rcsb pdb:6SV4|rcsb pdb:6T4Q|rcsb pdb:6T7I|rcsb pdb:6T7T|rcsb pdb:6T83|rcsb pdb:6TB3|rcsb pdb:6TNU|rcsb pdb:6YLG|rcsb pdb:6YLH|rcsb pdb:6YLX|rcsb pdb:6YLY|rcsb pdb:6Z6J|rcsb pdb:6Z6K|rcsb pdb:7AZY|rcsb pdb:7B7D|rcsb pdb:7BT6|rcsb pdb:7BTB|rcsb pdb:7NRC|dip:DIP-4826N	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:2Vdc8oRnT4Mz/j+EXQXrL3AszOc9606	rogid:TCDvdj9QlqdgRadKyIWG7ane1hw559292	intact-crc:C40EC43D2171CED2|rigid:KqIOTMa/9fGdg3f2mHv0SPhCTw0	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O43765	intact:EBI-11522265	intact:EBI-347996|ensembl:ENSP00000221566|ensembl:ENSP00000503397|ensembl:ENSP00000504495|uniprotkb:Q9BTZ9|intact:EBI-1045243|uniprotkb:Q6FIA9|uniprotkb:D6W610	-	psi-mi:sgta_human(display_long)|uniprotkb:SGTA(gene name)|psi-mi:SGTA(display_short)|uniprotkb:SGT(gene name synonym)|uniprotkb:Alpha-SGT(gene name synonym)|uniprotkb:Vpu-binding protein(gene name synonym)|uniprotkb:SGT1(gene name synonym)	psi-mi:pth2(display_short)|psi-mi:EBI-11522265(display_long)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11548852|imex:IM-24995-2784	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:4CPG|rcsb pdb:4GOD|rcsb pdb:4GOE|rcsb pdb:4GOF|reactome:R-HSA-9609523|rcsb pdb:2VYI|ensembl:ENSG00000104969(gene)|ensembl:ENST00000221566(transcript)|ensembl:ENST00000676943(transcript)|ensembl:ENST00000677149(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072380"(TRC complex)|go:"GO:0098850"(extrinsic component of synaptic vesicle membrane)|go:"GO:1903070"(negative regulation of ER-associated ubiquitin-dependent protein catabolic process)|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)|go:"GO:1903646"(positive regulation of chaperone-mediated protein folding)|go:"GO:1904288"(BAT3 complex binding)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR032374|mint:O43765|refseq:XP_011526480.1|refseq:NP_003012.1	-	-	-	no-uniprot-update:	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:r/Cyj4UJk/cS8QdrbjhTZMPCigI9606	rogid:pRGxsdHHpne2ORtwUYJZXHw7qPA4932	intact-crc:7436D32A8F0D7F55|rigid:Tr4HPuY4tbotOsKellP2JQdWRVc	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
intact:EBI-11522279	uniprotkb:O95994	-	intact:EBI-712648|ensembl:ENSP00000391490	psi-mi:hsp150(display_short)|psi-mi:EBI-11522279(display_long)	psi-mi:agr2_human(display_long)|uniprotkb:Secreted cement gland protein XAG-2 homolog(gene name synonym)|uniprotkb:HPC8(gene name synonym)|uniprotkb:AG2(gene name synonym)|uniprotkb:UNQ515/PRO1030(orf name)|uniprotkb:AGR2(gene name)|psi-mi:AGR2(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11548856|imex:IM-24995-2785	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	-	go:"GO:0005615"(extracellular space)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0042802"(identical protein binding)|go:"GO:0045742"(positive regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0048546"(digestive tract morphogenesis)|go:"GO:0048639"(positive regulation of developmental growth)|go:"GO:0060480"(lung goblet cell differentiation)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070254"(mucus secretion)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:1903896"(positive regulation of IRE1-mediated unfolded protein response)|go:"GO:1903899"(positive regulation of PERK-mediated unfolded protein response)|interpro:IPR036249|rcsb pdb:2LNS|rcsb pdb:2LNT|ensembl:ENSG00000106541(gene)|ensembl:ENST00000419304(transcript)|go:"GO:0002162"(dystroglycan binding)|go:"GO:0005154"(epidermal growth factor receptor binding)|refseq:NP_006399.1|refseq:XP_005249638.1|dip:DIP-48825N	-	no-uniprot-update:	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:6kfIxwLCGf2jj4GQK7oFLVnLfXU4932	rogid:E824a1MDXuGzk23ohjS7HAeEx5U9606	intact-crc:670697CD874F89EA|rigid:6Zb01R8bdSK9bglzfjUt4aN1QpQ	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O43765	uniprotkb:P00724	intact:EBI-347996|ensembl:ENSP00000221566|ensembl:ENSP00000503397|ensembl:ENSP00000504495|uniprotkb:Q9BTZ9|intact:EBI-1045243|uniprotkb:Q6FIA9|uniprotkb:D6W610	intact:EBI-9282|ensemblfungi:YIL162W|uniprotkb:Q12671|uniprotkb:D6VVC4	psi-mi:sgta_human(display_long)|uniprotkb:SGTA(gene name)|psi-mi:SGTA(display_short)|uniprotkb:SGT(gene name synonym)|uniprotkb:Alpha-SGT(gene name synonym)|uniprotkb:Vpu-binding protein(gene name synonym)|uniprotkb:SGT1(gene name synonym)	psi-mi:inv2_yeast(display_long)|uniprotkb:SUC2(gene name)|psi-mi:SUC2(display_short)|uniprotkb:YIL162W(locus name)|uniprotkb:Beta-fructofuranosidase 2(gene name synonym)|uniprotkb:Saccharase(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11548860|imex:IM-24995-2786	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:4CPG|rcsb pdb:4GOD|rcsb pdb:4GOE|rcsb pdb:4GOF|reactome:R-HSA-9609523|rcsb pdb:2VYI|ensembl:ENSG00000104969(gene)|ensembl:ENST00000221566(transcript)|ensembl:ENST00000676943(transcript)|ensembl:ENST00000677149(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072380"(TRC complex)|go:"GO:0098850"(extrinsic component of synaptic vesicle membrane)|go:"GO:1903070"(negative regulation of ER-associated ubiquitin-dependent protein catabolic process)|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)|go:"GO:1903646"(positive regulation of chaperone-mediated protein folding)|go:"GO:1904288"(BAT3 complex binding)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR032374|mint:O43765|refseq:XP_011526480.1|refseq:NP_003012.1	ensemblfungi:YIL162W(gene)|ensemblfungi:YIL162W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0004564"(beta-fructofuranosidase activity)|go:"GO:0004575"(sucrose alpha-glucosidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005987"(sucrose catabolic process)|go:"GO:0010147"(fructan catabolic process)|go:"GO:0034484"(raffinose catabolic process)|go:"GO:0051670"(inulinase activity)|go:"GO:0071944"(cell periphery)|go:"GO:1902927"(inulin catabolic process)|interpro:IPR001362(Glycoside hydrolase, family 32)|interpro:IPR013148(Glycosyl hydrolases family 32, N-terminal)|interpro:IPR013189(Glycosyl hydrolase family 32, C-terminal)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR018053|interpro:IPR023296|rcsb pdb:4EQV|refseq:NP_012104.1|sgd:S000001424|dip:DIP-5542N|mint:P00724	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:r/Cyj4UJk/cS8QdrbjhTZMPCigI9606	rogid:I6j4m4s8gvTdurEXs3Q7hTrpO30559292	intact-crc:2F822EB99AC8362A|rigid:v2A+BV0dFY1i3+2cxNb0J5rI+DE	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:E9PFK9	uniprotkb:P0CH08	intact:EBI-11523104|ensembl:ENSP00000403429	intact:EBI-11523108|uniprotkb:D6VVD9|uniprotkb:P04838|uniprotkb:P14796|uniprotkb:P61864|uniprotkb:Q6LA96|ensemblfungi:YIL148W|ensemblfungi:YKR094C	psi-mi:e9pfk9_human(display_long)|uniprotkb:RABGEF1(gene name)|psi-mi:RABGEF1(display_short)	psi-mi:rl40a_yeast(display_long)|uniprotkb:RPL40A(gene name)|psi-mi:RPL40A(display_short)|uniprotkb:UBI1(gene name synonym)|uniprotkb:YIL148W(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11548888|imex:IM-24995-2793	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000154710(gene)|ensembl:ENST00000439720(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|interpro:IPR002653(Zinc finger, A20-type)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR037191|interpro:IPR041545	rcsb pdb:5NDG|rcsb pdb:5NDV|rcsb pdb:5NDW|rcsb pdb:5OBM|rcsb pdb:6WOO|interpro:IPR000626(Ubiquitin)|interpro:IPR001975(Ribosomal protein L40e)|interpro:IPR019954|interpro:IPR019956|interpro:IPR029071|rcsb pdb:3J6X|rcsb pdb:3J6Y|rcsb pdb:3J77|rcsb pdb:3J78|rcsb pdb:4U3M|rcsb pdb:4U3N|rcsb pdb:4U3U|rcsb pdb:4U4N|rcsb pdb:4U4O|rcsb pdb:4U4Q|rcsb pdb:4U4R|rcsb pdb:4U4U|rcsb pdb:4U4Y|rcsb pdb:4U4Z|rcsb pdb:4U50|rcsb pdb:4U51|rcsb pdb:4U52|rcsb pdb:4U53|rcsb pdb:4U55|rcsb pdb:4U56|rcsb pdb:4U6F|rcsb pdb:4V6I|rcsb pdb:4V88|rcsb pdb:4V8T|rcsb pdb:4V8Y|rcsb pdb:4V8Z|rcsb pdb:5APN|rcsb pdb:5APO|refseq:NP_012118.1|refseq:NP_013020.3|sgd:S000001410|rcsb pdb:6TB3|rcsb pdb:6TNU|rcsb pdb:5DGE|rcsb pdb:5M1J|rcsb pdb:5MC6|rcsb pdb:5TGM|rcsb pdb:6EF3|rcsb pdb:6OIG|rcsb pdb:6OA9|rcsb pdb:6OAA|rcsb pdb:6QIK|rcsb pdb:6QT0|rcsb pdb:6QTZ|rcsb pdb:6R84|rcsb pdb:6R87|rcsb pdb:6RI5|rcsb pdb:5FCI|rcsb pdb:5FCJ|rcsb pdb:5DGF|rcsb pdb:5DGV|rcsb pdb:5LYB|rcsb pdb:5TGA|rcsb pdb:6HHQ|rcsb pdb:5DC3|rcsb pdb:5I4L|rcsb pdb:6N8M|rcsb pdb:6N8N|rcsb pdb:6N8O|rcsb pdb:6I7O|rcsb pdb:7AZY|rcsb pdb:7B7D|rcsb pdb:7NRC|rcsb pdb:7NRD|reactome:R-SCE-1169408|reactome:R-SCE-5656169|rcsb pdb:5GAK|rcsb pdb:6Q8Y|ensemblfungi:YIL148W(gene)|ensemblfungi:YIL148W_mRNA(transcript)|ensemblfungi:YKR094C(gene)|ensemblfungi:YKR094C_mRNA(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0031386"(protein tag)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042254"(ribosome biogenesis)|rcsb pdb:6HD7|rcsb pdb:5ON6|rcsb pdb:5DAT|rcsb pdb:5JUO|rcsb pdb:5JUP|rcsb pdb:5JUS|rcsb pdb:5JUT|rcsb pdb:5JUU|rcsb pdb:5T62|rcsb pdb:5T6R|interpro:IPR038587|rcsb pdb:5MEI|rcsb pdb:5TBW|rcsb pdb:6GQ1|rcsb pdb:6GQB|rcsb pdb:6GQV|rcsb pdb:6R86|rcsb pdb:6S47|rcsb pdb:6NYO|rcsb pdb:6T4Q|rcsb pdb:6T7I|rcsb pdb:6T7T|rcsb pdb:6T83|rcsb pdb:6SNT|rcsb pdb:6SV4|rcsb pdb:6XIQ|rcsb pdb:6Z6J|rcsb pdb:6Z6K	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/03/16	rogid:JDHW8cuCB2z39j6a+LlkARnLfYo9606	rogid:6+5uVAktIpS9HyPHQ6BzXEuT/y0559292	intact-crc:9F984AF235CC595C|rigid:Wx9NGINsPfl18eLv0ZOa7FGIPRA	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P09467	uniprotkb:P09201	intact:EBI-712740|ensembl:ENSP00000364475|ensembl:ENSP00000408025|uniprotkb:O75571|uniprotkb:Q53F94|uniprotkb:Q96E46	intact:EBI-6744|uniprotkb:D6VZ13|ensemblfungi:YLR377C	psi-mi:f16p1_human(display_long)|uniprotkb:D-fructose-1,6-bisphosphate 1-phosphohydrolase 1(gene name synonym)|uniprotkb:FBP1(gene name)|psi-mi:FBP1(display_short)|uniprotkb:FBP(gene name synonym)|uniprotkb:Liver FBPase(gene name synonym)	psi-mi:f16p_yeast(display_long)|uniprotkb:FBP1(gene name)|psi-mi:FBP1(display_short)|uniprotkb:YLR377C(locus name)|uniprotkb:L8039.18(orf name)|uniprotkb:D-fructose-1,6-bisphosphate 1-phosphohydrolase(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11548884|imex:IM-24995-2792	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000375326(transcript)|ensembl:ENST00000415431(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005986"(sucrose biosynthetic process)|go:"GO:0006000"(fructose metabolic process)|go:"GO:0006002"(fructose 6-phosphate metabolic process)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006111"(regulation of gluconeogenesis)|go:"GO:0016208"(AMP binding)|go:"GO:0016311"(dephosphorylation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030388"(fructose 1,6-bisphosphate metabolic process)|go:"GO:0035690"|go:"GO:0042132"(fructose 1,6-bisphosphate 1-phosphatase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0045820"(negative regulation of glycolytic process)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0046872"(metal ion binding)|go:"GO:0048029"(monosaccharide binding)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071286"(cellular response to magnesium ion)|interpro:IPR000146(Inositol phosphatase/fructose-1,6-bisphosphatase)|interpro:IPR020548|interpro:IPR028343|interpro:IPR033391|interpro:IPR044015|mint:P09467|rcsb pdb:1FTA|rcsb pdb:2FHY|rcsb pdb:2FIE|rcsb pdb:2FIX|rcsb pdb:2JJK|rcsb pdb:2VT5|rcsb pdb:2WBB|rcsb pdb:2WBD|rcsb pdb:2Y5K|rcsb pdb:2Y5L|rcsb pdb:3A29|rcsb pdb:3KBZ|rcsb pdb:3KC0|ensembl:ENSG00000165140(gene)|rcsb pdb:3KC1|rcsb pdb:4MJO|rcsb pdb:5LDZ|rcsb pdb:5PZR|rcsb pdb:5PZS|rcsb pdb:5PZT|rcsb pdb:5PZU|rcsb pdb:5PZV|rcsb pdb:5PZW|rcsb pdb:5PZX|rcsb pdb:5PZY|rcsb pdb:5PZZ|rcsb pdb:5Q00|rcsb pdb:5Q01|rcsb pdb:5Q02|rcsb pdb:5Q03|rcsb pdb:5Q04|rcsb pdb:5Q05|rcsb pdb:5Q06|rcsb pdb:5Q07|rcsb pdb:5Q08|rcsb pdb:5Q09|rcsb pdb:5PZQ|rcsb pdb:5Q0A|rcsb pdb:5Q0B|rcsb pdb:6LS5|rcsb pdb:6LW2|rcsb pdb:7C9Q|rcsb pdb:7CVN|reactome:R-HSA-70263|refseq:NP_000498.2|refseq:NP_001121100.1|dip:DIP-46677N	refseq:NP_013481.3|sgd:S000004369|dip:DIP-3986N|mint:P09201|ensemblfungi:YLR377C(gene)|ensemblfungi:YLR377C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005986"(sucrose biosynthetic process)|go:"GO:0006000"(fructose metabolic process)|go:"GO:0006002"(fructose 6-phosphate metabolic process)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0030388"(fructose 1,6-bisphosphate metabolic process)|go:"GO:0042132"(fructose 1,6-bisphosphate 1-phosphatase activity)|go:"GO:0042597"(periplasmic space)|go:"GO:0046872"(metal ion binding)|go:"GO:0072593"(reactive oxygen species metabolic process)|interpro:IPR000146(Inositol phosphatase/fructose-1,6-bisphosphatase)|interpro:IPR020548|interpro:IPR028343|interpro:IPR033391|interpro:IPR044015|rcsb pdb:7NS5|reactome:R-SCE-70263	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:DnrtyrU5WL/7ut1qWv7LndveJT89606	rogid:hvvSZcZrdcN9FcOmFzY/jCYIcJY559292	intact-crc:4149AAD8B095E78D|rigid:/hmm1xVCnVzWSAVYiTg4jul4030	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P06782	uniprotkb:O43597	intact:EBI-17516|uniprotkb:D6VTA0|ensemblfungi:YDR477W	intact:EBI-742487|uniprotkb:Q5T6Z7|ensembl:ENSP00000366306|ensembl:ENSP00000366308|uniprotkb:B2R9J9	psi-mi:snf1_yeast(display_long)|uniprotkb:SNF1(gene name)|psi-mi:SNF1(display_short)|uniprotkb:CAT1(gene name synonym)|uniprotkb:CCR1(gene name synonym)|uniprotkb:GLC2(gene name synonym)|uniprotkb:PAS14(gene name synonym)|uniprotkb:Sucrose nonfermentating protein 1(gene name synonym)|uniprotkb:D8035.20(orf name)|uniprotkb:YDR477W(locus name)	psi-mi:spy2_human(display_long)|uniprotkb:SPRY2(gene name)|psi-mi:SPRY2(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11548872|imex:IM-24995-2789	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010765.3|sgd:S000002885|ensemblfungi:YDR477W(gene)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0071940"(fungal-type cell wall assembly)|go:"GO:0090606"(single-species surface biofilm formation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900436"(positive regulation of filamentous growth of a population of unicellular organisms in response to starvation)|go:"GO:2000222"(positive regulation of pseudohyphal growth)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013896(Ubiquitin-associated region 2)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR028375|interpro:IPR032270|rcsb pdb:2FH9|rcsb pdb:2QLV|rcsb pdb:3DAE|rcsb pdb:3HYH|rcsb pdb:3MN3|rcsb pdb:3T4N|rcsb pdb:3TDH|rcsb pdb:3TE5|reactome:R-SCE-1632852|reactome:R-SCE-163680|reactome:R-SCE-200425|reactome:R-SCE-380972|ensemblfungi:YDR477W_mRNA(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000144"(cellular bud neck septin ring)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004679"(AMP-activated protein kinase activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005641"(nuclear envelope lumen)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0007155"(cell adhesion)|go:"GO:0016239"(positive regulation of macroautophagy)|dip:DIP-18N|mint:P06782	refseq:NP_005833.1|rcsb pdb:5HL0|reactome:R-HSA-1295596|reactome:R-HSA-182971|rcsb pdb:5HKZ|ensembl:ENST00000377102(transcript)|ensembl:ENST00000377104(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|ensembl:ENSG00000136158(gene)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030291"(protein serine/threonine kinase inhibitor activity)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031345"(negative regulation of cell projection organization)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0032587"(ruffle membrane)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0045165"(cell fate commitment)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048513"(animal organ development)|go:"GO:0051387"(negative regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060437"(lung growth)|go:"GO:0060449"(bud elongation involved in lung branching)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:1900747"(negative regulation of vascular endothelial growth factor signaling pathway)|go:"GO:1902747"(negative regulation of lens fiber cell differentiation)|go:"GO:1990752"(microtubule end)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR007875(Sprouty)|interpro:IPR030780|mint:O43597|rcsb pdb:3BUM|rcsb pdb:3OB1|rcsb pdb:5HKY|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|refseq:NP_001305465.1|refseq:NP_001305466.1|refseq:NP_001305467.1	-	crc64:F5C63565C986C4E3	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:O/SAW1kJE3fpoXPHGLG01i9RePs559292	rogid:u1omauzisc6MdZlogMotUmtauSI9606	intact-crc:CAAA141D2E2AFE37|rigid:/pIvrusIwTiKh0zizHtESKccyf0	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8N5R6	uniprotkb:P06782	intact:EBI-740841|intact:EBI-953781|uniprotkb:B3KQ49|uniprotkb:A8K3U4|uniprotkb:A8MPQ6|uniprotkb:A8MV61|uniprotkb:A8MVU9|uniprotkb:Q9H5Q6|uniprotkb:Q8TAX6|intact:EBI-2320546|intact:EBI-11522976	intact:EBI-17516|uniprotkb:D6VTA0|ensemblfungi:YDR477W	psi-mi:ccd33_human(display_long)|uniprotkb:CCDC33(gene name)|psi-mi:CCDC33(display_short)|uniprotkb:Cancer/testis antigen 61(gene name synonym)	psi-mi:snf1_yeast(display_long)|uniprotkb:SNF1(gene name)|psi-mi:SNF1(display_short)|uniprotkb:CAT1(gene name synonym)|uniprotkb:CCR1(gene name synonym)|uniprotkb:GLC2(gene name synonym)|uniprotkb:PAS14(gene name synonym)|uniprotkb:Sucrose nonfermentating protein 1(gene name synonym)|uniprotkb:D8035.20(orf name)|uniprotkb:YDR477W(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11548876|imex:IM-24995-2790	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_079331.3|interpro:IPR000008(C2 calcium-dependent membrane targeting)|go:"GO:0005777"(peroxisome)|refseq:NP_001274110.1|refseq:NP_877592.2|mint:Q8N5R6|interpro:IPR035892|interpro:IPR039889	refseq:NP_010765.3|sgd:S000002885|ensemblfungi:YDR477W(gene)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0071940"(fungal-type cell wall assembly)|go:"GO:0090606"(single-species surface biofilm formation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900436"(positive regulation of filamentous growth of a population of unicellular organisms in response to starvation)|go:"GO:2000222"(positive regulation of pseudohyphal growth)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013896(Ubiquitin-associated region 2)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR028375|interpro:IPR032270|rcsb pdb:2FH9|rcsb pdb:2QLV|rcsb pdb:3DAE|rcsb pdb:3HYH|rcsb pdb:3MN3|rcsb pdb:3T4N|rcsb pdb:3TDH|rcsb pdb:3TE5|reactome:R-SCE-1632852|reactome:R-SCE-163680|reactome:R-SCE-200425|reactome:R-SCE-380972|ensemblfungi:YDR477W_mRNA(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000144"(cellular bud neck septin ring)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004679"(AMP-activated protein kinase activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005641"(nuclear envelope lumen)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0007155"(cell adhesion)|go:"GO:0016239"(positive regulation of macroautophagy)|dip:DIP-18N|mint:P06782	-	-	crc64:F5C63565C986C4E3	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2021/11/30	rogid:eEIn7pQyfdHWx8TeLJpYy0i/gww9606	rogid:O/SAW1kJE3fpoXPHGLG01i9RePs559292	intact-crc:660CA94EAC3EB182|rigid:ZRLG728wbypxjsqZJneIKHvxyVk	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O94983-5	uniprotkb:P06787	intact:EBI-10176008	intact:EBI-3976|uniprotkb:D6VQA8|ensemblfungi:YBR109C	psi-mi:o94983-5(display_long)|uniprotkb:KIAA0909(gene name synonym)|uniprotkb:CAMTA2(gene name)|psi-mi:CAMTA2(display_short)	psi-mi:calm_yeast(display_long)|uniprotkb:YBR0904(orf name)|uniprotkb:YBR109C(locus name)|uniprotkb:CMD1(gene name)|psi-mi:CMD1(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11548880|imex:IM-24995-2791	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-936534(isoform-parent)|uniprotkb:O94983-5(isoform-parent)	refseq:NP_009667.1|sgd:S000000313|dip:DIP-536N|mint:P06787|ensemblfungi:YBR109C(gene)|ensemblfungi:YBR109C_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0000742"(karyogamy involved in conjugation with cellular fusion)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005823"(central plaque of spindle pole body)|go:"GO:0005933"(cellular bud)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0006897"(endocytosis)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007114"(cell budding)|go:"GO:0016237"(lysosomal microautophagy)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0042144"(vacuole fusion, non-autophagic)|go:"GO:0043332"(mating projection tip)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051019"(mitogen-activated protein kinase binding)|go:"GO:0051300"(spindle pole body organization)|go:"GO:1903525"(regulation of membrane tubulation)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR039030|rcsb pdb:1F54|rcsb pdb:1F55|rcsb pdb:1LKJ|rcsb pdb:2LHH|rcsb pdb:2LHI|rcsb pdb:6OQQ|reactome:R-SCE-111932|reactome:R-SCE-114608|reactome:R-SCE-1474151|reactome:R-SCE-203615|reactome:R-SCE-2871809|reactome:R-SCE-4086398|reactome:R-SCE-442729|reactome:R-SCE-5218920|reactome:R-SCE-5607763|reactome:R-SCE-5626467|reactome:R-SCE-6798695|reactome:R-SCE-9009391|reactome:R-SCE-9619229	-	-	crc64:819ED1AD5D9400D3	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:vzdEZ0CgkqevyH4Na04MPr4O6TM9606	rogid:jyNQ4XuG4o2uZi6ztTIMCcgbQFM559292	intact-crc:BFF1E16A2D8C8A47|rigid:15hU7apRfQRdlXDSqgd2L1/aR6k	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O95273	uniprotkb:P14905	intact:EBI-748961|uniprotkb:A8K3Q0|uniprotkb:A8K3U2|uniprotkb:Q6ZQN9|uniprotkb:Q7Z519|uniprotkb:Q8NBS7|uniprotkb:Q8NBY2|uniprotkb:Q9NS19|uniprotkb:Q9NYH3|uniprotkb:Q9UHX9|ensembl:ENSP00000300213	intact:EBI-4163|uniprotkb:D6VSI0|ensemblfungi:YDR197W	psi-mi:ccdb1_human(display_long)|uniprotkb:Grap2 and cyclin-D-interacting protein(gene name synonym)|uniprotkb:Human homolog of Maid(gene name synonym)|uniprotkb:CCNDBP1(gene name)|psi-mi:CCNDBP1(display_short)|uniprotkb:DIP1(gene name synonym)|uniprotkb:GCIP(gene name synonym)|uniprotkb:HHM(gene name synonym)	psi-mi:cbs2_yeast(display_long)|uniprotkb:CBS2(gene name)|psi-mi:CBS2(display_short)|uniprotkb:CBP7(gene name synonym)|uniprotkb:YDR197W(locus name)|uniprotkb:YD9346.08(orf name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11548908|imex:IM-24995-2798	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_036274.3|ensembl:ENSG00000166946(gene)|ensembl:ENST00000300213(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0016604"(nuclear body)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR026907|mint:O95273|rcsb pdb:3AY5	refseq:NP_010483.1|sgd:S000002605|interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|interpro:IPR013752(Ketopantoate reductase ApbA/PanE, C-terminal)|interpro:IPR013328(Dehydrogenase, multihelical)|ensemblfungi:YDR197W(gene)|ensemblfungi:YDR197W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005761"(mitochondrial ribosome)|go:"GO:0008677"(2-dehydropantoate 2-reductase activity)|go:"GO:0031314"(extrinsic component of mitochondrial inner membrane)|go:"GO:0045182"(translation regulator activity)|go:"GO:0050661"(NADP binding)|go:"GO:0070131"(positive regulation of mitochondrial translation)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Vi9aoFc+Mov6P3X6KGmsTxXqxvM9606	rogid:KEEVJQEjHPVx7AU4JFmwGnoEptU559292	intact-crc:15DC567D0A1C632D|rigid:q/3T4XXuCPOQCtjMxHiqDceUpZU	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P06782	uniprotkb:P14373	intact:EBI-17516|uniprotkb:D6VTA0|ensemblfungi:YDR477W	intact:EBI-719493|uniprotkb:A2BE15|uniprotkb:Q5RJA8|uniprotkb:Q5ST26|uniprotkb:Q6LA73|uniprotkb:Q6NXR9|uniprotkb:Q9BZY6|uniprotkb:Q9UJL3|ensembl:ENSP00000383555|ensembl:ENSP00000392787|ensembl:ENSP00000405229|ensembl:ENSP00000414793|ensembl:ENSP00000366404	psi-mi:snf1_yeast(display_long)|uniprotkb:SNF1(gene name)|psi-mi:SNF1(display_short)|uniprotkb:CAT1(gene name synonym)|uniprotkb:CCR1(gene name synonym)|uniprotkb:GLC2(gene name synonym)|uniprotkb:PAS14(gene name synonym)|uniprotkb:Sucrose nonfermentating protein 1(gene name synonym)|uniprotkb:D8035.20(orf name)|uniprotkb:YDR477W(locus name)	psi-mi:tri27_human(display_long)|uniprotkb:TRIM27(gene name)|psi-mi:TRIM27(display_short)|uniprotkb:RNF76(gene name synonym)|uniprotkb:RFP(gene name synonym)|uniprotkb:Ret finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 27(gene name synonym)|uniprotkb:RING finger protein 76(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM27(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11548904|imex:IM-24995-2797	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010765.3|sgd:S000002885|ensemblfungi:YDR477W(gene)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0071940"(fungal-type cell wall assembly)|go:"GO:0090606"(single-species surface biofilm formation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900436"(positive regulation of filamentous growth of a population of unicellular organisms in response to starvation)|go:"GO:2000222"(positive regulation of pseudohyphal growth)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013896(Ubiquitin-associated region 2)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR028375|interpro:IPR032270|rcsb pdb:2FH9|rcsb pdb:2QLV|rcsb pdb:3DAE|rcsb pdb:3HYH|rcsb pdb:3MN3|rcsb pdb:3T4N|rcsb pdb:3TDH|rcsb pdb:3TE5|reactome:R-SCE-1632852|reactome:R-SCE-163680|reactome:R-SCE-200425|reactome:R-SCE-380972|ensemblfungi:YDR477W_mRNA(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000144"(cellular bud neck septin ring)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004679"(AMP-activated protein kinase activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005641"(nuclear envelope lumen)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0007155"(cell adhesion)|go:"GO:0016239"(positive regulation of macroautophagy)|dip:DIP-18N|mint:P06782	refseq:NP_006501.1|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0090281"(negative regulation of calcium ion import)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR020457|interpro:IPR035791|interpro:IPR043136|mint:P14373|reactome:R-HSA-3232142|reactome:R-HSA-9635465|reactome:R-HSA-8948751|ensembl:ENSG00000204713(gene)|ensembl:ENSG00000215641(gene)|ensembl:ENSG00000229006(gene)|ensembl:ENSG00000234495(gene)|ensembl:ENSG00000237071(gene)|ensembl:ENST00000377199(transcript)|ensembl:ENST00000400720(transcript)|ensembl:ENST00000431123(transcript)|ensembl:ENST00000435528(transcript)|ensembl:ENST00000437160(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001650"(fibrillar center)|go:"GO:0002820"(negative regulation of adaptive immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)	-	crc64:F5C63565C986C4E3	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:O/SAW1kJE3fpoXPHGLG01i9RePs559292	rogid:dsfH5OUghD8KSaTz1SFw9OYVTK49606	intact-crc:2D281DBFB27221B3|rigid:h7VfHQetYAIiUYbPMZSfzqd4VHM	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P12612	uniprotkb:O60232	intact:EBI-19045|uniprotkb:D6VSJ6|ensemblfungi:YDR212W	intact:EBI-741415|ensembl:ENSP00000312318	psi-mi:tcpa_yeast(display_long)|uniprotkb:TCP1(gene name)|psi-mi:TCP1(display_short)|uniprotkb:CCT1(gene name synonym)|uniprotkb:YDR212W(locus name)|uniprotkb:YD8142.13(orf name)|uniprotkb:YD8142B.04(orf name)|uniprotkb:CCT-alpha(gene name synonym)	psi-mi:znrd2_human(display_long)|uniprotkb:ZNRD2(gene name)|psi-mi:ZNRD2(display_short)|uniprotkb:Autoantigen p27(gene name synonym)|uniprotkb:SSSCA1(gene name synonym)|uniprotkb:Sjoegren syndrome/scleroderma autoantigen 1(gene name synonym)|uniprotkb:Zinc ribbon domain-containing protein 2(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11548892|imex:IM-24995-2794	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010498.1|sgd:S000002620|ensemblfungi:YDR212W(gene)|ensemblfungi:YDR212W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012715(T-complex protein 1, alpha subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|rcsb pdb:4V81|rcsb pdb:4V8R|rcsb pdb:4V94|rcsb pdb:5GW4|rcsb pdb:5GW5|rcsb pdb:6KRD|rcsb pdb:6KRE|rcsb pdb:6KS6|rcsb pdb:6KS7|rcsb pdb:6KS8|reactome:R-SCE-390471|reactome:R-SCE-6814122|dip:DIP-2965N|mint:P12612	refseq:NP_006387.1|ensembl:ENSG00000173465(gene)|ensembl:ENST00000309328(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0051301"(cell division)|interpro:IPR009563(Sjogrens syndrome scleroderma autoantigen 1)|rcsb pdb:6HCZ	-	crc64:02C625D329359E61	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:xWMsvY106Y6yQ54SOif2UlScafM559292	rogid:Uou80pZneoL39/0YYzb1TAbiB2I9606	intact-crc:625FC7612220EE9D|rigid://TjGLfHSuH0wACVj1nKRpTLARQ	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
intact:EBI-11522220	uniprotkb:P14136	-	intact:EBI-744302|uniprotkb:Q53H98|uniprotkb:Q5D055|uniprotkb:Q6ZQS3|uniprotkb:Q7Z5J6|uniprotkb:Q7Z5J7|uniprotkb:Q96KS4|uniprotkb:Q96P18|uniprotkb:Q9UFD0|uniprotkb:B2RD44|uniprotkb:D3DX59|intact:EBI-3909365|uniprotkb:E9PAX3|ensembl:ENSP00000466598|uniprotkb:A7REI1	psi-mi:lsb3(display_short)|psi-mi:EBI-11522220(display_long)	psi-mi:gfap_human(display_long)|uniprotkb:GFAP(gene name)|psi-mi:GFAP(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11548896|imex:IM-24995-2795	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001124491.1|refseq:NP_001229305.1|refseq:NP_002046.1|ensembl:ENSG00000131095(gene)|ensembl:ENST00000588735(transcript)|go:"GO:0005178"(integrin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0009611"(response to wounding)|go:"GO:0010467"(gene expression)|go:"GO:0010625"(positive regulation of Schwann cell proliferation)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0014002"(astrocyte development)|go:"GO:0019900"(kinase binding)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0031102"(neuron projection regeneration)|go:"GO:0042802"(identical protein binding)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0044297"(cell body)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0051580"(regulation of neurotransmitter uptake)|go:"GO:0060020"(Bergmann glial cell differentiation)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0070779"(D-aspartate import across plasma membrane)|go:"GO:0097450"(astrocyte end-foot)|go:"GO:0098574"(cytoplasmic side of lysosomal membrane)|go:"GO:1904714"(regulation of chaperone-mediated autophagy)|interpro:IPR006821(Intermediate filament, DNA-binding region)|interpro:IPR018039|interpro:IPR027701|interpro:IPR039008|mint:P14136|rcsb pdb:6A9P|reactome:R-HSA-1251985|reactome:R-HSA-9613829	-	no-uniprot-update:	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:lsGJZWImagMoiiCZztCcxCn2LlU4932	rogid:Pz4JW0WjMjBYILTDSX9jUmMqWhg9606	intact-crc:FC701492A6C42E35|rigid:lWp7O9BNA3tICjiU1HeSWb4cvmo	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
intact:EBI-11522220	uniprotkb:P14317	-	intact:EBI-750369|uniprotkb:B4DQ69|uniprotkb:Q53Y93|uniprotkb:Q6IBK9|uniprotkb:Q9UDK0|ensembl:ENSP00000320176	psi-mi:lsb3(display_short)|psi-mi:EBI-11522220(display_long)	psi-mi:hcls1_human(display_long)|uniprotkb:Hematopoietic cell-specific LYN substrate 1(gene name synonym)|uniprotkb:LckBP1(gene name synonym)|uniprotkb:p75(gene name synonym)|uniprotkb:HCLS1(gene name)|psi-mi:HCLS1(display_short)|uniprotkb:HS1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11548900|imex:IM-24995-2796	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSP00000320176|ensembl:ENST00000495491|ensembl:ENSP00000418299|refseq:NP_001278970.1|refseq:NP_005326.2|ensembl:ENSG00000180353(gene)|ensembl:ENST00000314583(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009725"(response to hormone)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030427"(site of polarized growth)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030854"(positive regulation of granulocyte differentiation)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045651"(positive regulation of macrophage differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0051015"(actin filament binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:2000107"(negative regulation of leukocyte apoptotic process)|go:"GO:2000251"(positive regulation of actin cytoskeleton reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR003134(Hs1/Cortactin)|interpro:IPR028534|interpro:IPR036028|mint:P14317	-	no-uniprot-update:	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:lsGJZWImagMoiiCZztCcxCn2LlU4932	rogid:sViasWf8ZiLb/dmYn3VEr7t2L0Y9606	intact-crc:3AC0654E5CB9A0F5|rigid:pFBbhqbSkpRlbGtTdrie/j+YySs	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O96006	uniprotkb:P17157	intact:EBI-740037|uniprotkb:Q96BY4|ensembl:ENSP00000370616|ensembl:ENSP00000370620|ensembl:ENSP00000370621|ensembl:ENSP00000498725	intact:EBI-13327|uniprotkb:Q03089|uniprotkb:Q06888|ensemblfungi:YPL031C|uniprotkb:D6W3Y2	psi-mi:zbed1_human(display_long)|uniprotkb:ZBED1(gene name)|psi-mi:ZBED1(display_short)|uniprotkb:ALTE(gene name synonym)|uniprotkb:DREF(gene name synonym)|uniprotkb:KIAA0785(gene name synonym)|uniprotkb:TRAMP(gene name synonym)|uniprotkb:dREF homolog(gene name synonym)|uniprotkb:Putative Ac-like transposable element(gene name synonym)|uniprotkb:DNA replication-related element-binding factor(gene name synonym)|uniprotkb:Zinc finger BED domain-containing protein 1(gene name synonym)|uniprotkb:hDREF(gene name synonym)	psi-mi:pho85_yeast(display_long)|uniprotkb:PHO85(gene name)|psi-mi:PHO85(display_short)|uniprotkb:SSG3(gene name synonym)|uniprotkb:P7102.18A(orf name)|uniprotkb:Serine/threonine-protein kinase PHO85(gene name synonym)|uniprotkb:Negative regulator of the PHO system(gene name synonym)|uniprotkb:YPL031C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11548924|imex:IM-24995-2802	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164606.1|refseq:NP_001164607.1|refseq:NP_004720.1|ensembl:ENSG00000214717(gene)|ensembl:ENST00000381218(transcript)|ensembl:ENST00000381222(transcript)|ensembl:ENST00000381223(transcript)|ensembl:ENST00000652001(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0031965"(nuclear membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044828"(negative regulation by host of viral genome replication)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0061665"(SUMO ligase activity)|go:"GO:1990466"(protein autosumoylation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003656(Zinc finger, BED-type predicted)|interpro:IPR008906(HAT dimerisation)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR036236|mint:O96006|rcsb pdb:2CT5|reactome:R-HSA-4551638|go:"GO:0005813"(centrosome)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016605"(PML body)	refseq:NP_015294.1|sgd:S000005952|ensemblfungi:YPL031C(gene)|ensemblfungi:YPL031C_mRNA(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016242"(negative regulation of macroautophagy)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032878"(regulation of establishment or maintenance of cell polarity)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045719"(negative regulation of glycogen biosynthetic process)|go:"GO:0045936"(negative regulation of phosphate metabolic process)|go:"GO:0046822"(regulation of nucleocytoplasmic transport)|go:"GO:0050849"(negative regulation of calcium-mediated signaling)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0005737"(cytoplasm)|rcsb pdb:2PK9|rcsb pdb:2PMI|rcsb pdb:4KRC|rcsb pdb:4KRD|go:"GO:0005634"(nucleus)|go:"GO:0071073"(positive regulation of phospholipid biosynthetic process)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901987"(regulation of cell cycle phase transition)|go:"GO:1990860"(Pho85-Pho80 CDK-cyclin complex)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P17157|dip:DIP-1493N	-	-	crc64:246A4358870B00EC	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:jl97ZV2Kz5YAmQKktWt/wk7OkRw9606	rogid:hrRlpgrzGGTT3/GQ5x0LgsjaGeE559292	intact-crc:81C80F592E483658|rigid:bv1kpjcMnZ71+67yBuT1w6rQrXM	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O75477	uniprotkb:P15303	intact:EBI-359299|uniprotkb:B0QZ42|uniprotkb:Q53HV0|ensembl:ENSP00000384900|ensembl:ENSP00000410964|intact:EBI-21351077|uniprotkb:D3DR65	intact:EBI-16584|ensemblfungi:YPR181C|uniprotkb:D6W4I1	psi-mi:erln1_human(display_long)|uniprotkb:KEO4(gene name synonym)|uniprotkb:ERLIN1(gene name)|psi-mi:ERLIN1(display_short)|uniprotkb:C10orf69(gene name synonym)|uniprotkb:KE04(gene name synonym)|uniprotkb:SPFH1(gene name synonym)|uniprotkb:Endoplasmic reticulum lipid raft-associated protein 1(gene name synonym)|uniprotkb:Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 1(gene name synonym)|uniprotkb:Protein KE04(gene name synonym)	psi-mi:sec23_yeast(display_long)|uniprotkb:SEC23(gene name)|psi-mi:SEC23(display_short)|uniprotkb:P9705.14(orf name)|uniprotkb:YPR181C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11548912|imex:IM-24995-2799	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001094096.1|refseq:NP_006450.2|ensembl:ENSG00000107566(gene)|ensembl:ENST00000407654(transcript)|ensembl:ENST00000421367(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032933"(SREBP signaling pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045541"(negative regulation of cholesterol biosynthetic process)|go:"GO:0045717"(negative regulation of fatty acid biosynthetic process)|interpro:IPR001107(Band 7 protein)|interpro:IPR033294|interpro:IPR036013|mint:O75477|reactome:R-HSA-382556|reactome:R-HSA-5678895|refseq:NP_001334786.1|refseq:NP_001334788.1|refseq:NP_001334789.1|refseq:NP_001334790.1	refseq:NP_015507.1|sgd:S000006385|ensemblfungi:YPR181C(gene)|ensemblfungi:YPR181C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003400"(regulation of COPII vesicle coating)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016236"(macroautophagy)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0061709"(reticulophagy)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:0090110"(COPII-coated vesicle cargo loading)|interpro:IPR006895(Zinc finger, Sec23/Sec24-type)|interpro:IPR006896(Sec23/Sec24 trunk region)|interpro:IPR006900(Sec23/Sec24 helical region)|interpro:IPR007123(Gelsolin region)|interpro:IPR012990(Sec23/Sec24 beta-sandwich)|interpro:IPR029006|interpro:IPR036174|interpro:IPR036175|interpro:IPR036180|interpro:IPR036465|interpro:IPR037364|interpro:IPR037550|rcsb pdb:1M2O|rcsb pdb:2QTV|rcsb pdb:4BZI|rcsb pdb:6GNI|rcsb pdb:6ZGA|reactome:R-SCE-204005|reactome:R-SCE-5694530|reactome:R-SCE-983170|rcsb pdb:1M2V|dip:DIP-2232N|mint:P15303	-	-	crc64:69811913848265FB	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2019/05/28	rogid:HycFhL5qL5GLmaIIc9NtTcBbu1M9606	rogid:IqC3qOrbef6aMHBztUW5+7DZ4IQ559292	intact-crc:7A780A9D8A19A1E3|rigid:uipxd6WuchHbeGrUAlWl4Mm1AYo	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P15625	uniprotkb:O15162	intact:EBI-18678|uniprotkb:D6VTK8|ensemblfungi:YFL022C	intact:EBI-740019|ensembl:ENSP00000345494|uniprotkb:B2R8H8|uniprotkb:B4DTE8	psi-mi:syfa_yeast(display_long)|uniprotkb:FRS2(gene name)|psi-mi:FRS2(display_short)|uniprotkb:Phenylalanyl-tRNA synthetase alpha subunit(gene name synonym)|uniprotkb:YFL022C(locus name)	psi-mi:pls1_human(display_long)|uniprotkb:PLSCR1(gene name)|psi-mi:PLSCR1(display_short)|uniprotkb:"Ca(2+)-dependent phospholipid scramblase 1"(gene name synonym)|uniprotkb:Erythrocyte phospholipid scramblase(gene name synonym)|uniprotkb:MmTRA1b(gene name synonym)|uniprotkb:"Mg(2+)-dependent nuclease"(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11548916|imex:IM-24995-2800	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_116631.1|sgd:S000001872|ensemblfungi:YFL022C(gene)|ensemblfungi:YFL022C_mRNA(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0002161"(aminoacyl-tRNA editing activity)|go:"GO:0004826"(phenylalanine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006432"(phenylalanyl-tRNA aminoacylation)|go:"GO:0009328"(phenylalanine-tRNA ligase complex)|interpro:IPR002319(Phenylalanyl-tRNA synthetase, class IIc)|interpro:IPR004529(Phenylalanyl-tRNA synthetase, class IIc, alpha subunit)|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR040586|interpro:IPR040725|dip:DIP-5428N|mint:P15625	ensembl:ENSG00000188313(gene)|ensembl:ENST00000342435(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001618"(virus receptor activity)|go:"GO:0003677"(DNA binding)|go:"GO:0004518"(nuclease activity)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006659"(phosphatidylserine biosynthetic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0006953"(acute-phase response)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010288"(response to lead ion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0017121"(plasma membrane phospholipid scrambling)|go:"GO:0017124"(SH3 domain binding)|ensembl:ENSP00000345494|ensembl:ENST00000448787|ensembl:ENSP00000411675|refseq:NP_066928.1|go:"GO:0017128"(phospholipid scramblase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030168"(platelet activation)|go:"GO:0032791"(lead ion binding)|go:"GO:0033003"(regulation of mast cell activation)|go:"GO:0035456"(response to interferon-beta)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0045340"(mercury ion binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0051607"(defense response to virus)|go:"GO:0060368"(regulation of Fc receptor mediated stimulatory signaling pathway)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070782"(phosphatidylserine exposure on apoptotic cell surface)|go:"GO:1905820"(positive regulation of chromosome separation)|go:"GO:2000373"("positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity")|interpro:IPR005552(Scramblase)|mint:O15162|rcsb pdb:1Y2A|refseq:XP_011511209.1|refseq:XP_011511206.1|refseq:XP_005247595.1|refseq:XP_011511208.1|refseq:XP_016862118.1	-	crc64:50B7EAC675AB559B	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:hOEtrjcfIHQLY9FwCDb3XI593A4559292	rogid:XudfvUkrZbB28t9tpFkokgnDFGc9606	intact-crc:48A02F84FD561DB4|rigid:7WyGodAFnXD8EApEF8VHsdlfy+A	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P14373	uniprotkb:P15705	intact:EBI-719493|uniprotkb:A2BE15|uniprotkb:Q5RJA8|uniprotkb:Q5ST26|uniprotkb:Q6LA73|uniprotkb:Q6NXR9|uniprotkb:Q9BZY6|uniprotkb:Q9UJL3|ensembl:ENSP00000383555|ensembl:ENSP00000392787|ensembl:ENSP00000405229|ensembl:ENSP00000414793|ensembl:ENSP00000366404	intact:EBI-18418|uniprotkb:D6W293|ensemblfungi:YOR027W	psi-mi:tri27_human(display_long)|uniprotkb:TRIM27(gene name)|psi-mi:TRIM27(display_short)|uniprotkb:RNF76(gene name synonym)|uniprotkb:RFP(gene name synonym)|uniprotkb:Ret finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 27(gene name synonym)|uniprotkb:RING finger protein 76(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM27(gene name synonym)	psi-mi:sti1_yeast(display_long)|uniprotkb:STI1(gene name)|psi-mi:STI1(display_short)|uniprotkb:OR26.17(orf name)|uniprotkb:YOR027W(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11548920|imex:IM-24995-2801	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006501.1|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0090281"(negative regulation of calcium ion import)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR020457|interpro:IPR035791|interpro:IPR043136|mint:P14373|reactome:R-HSA-3232142|reactome:R-HSA-9635465|reactome:R-HSA-8948751|ensembl:ENSG00000204713(gene)|ensembl:ENSG00000215641(gene)|ensembl:ENSG00000229006(gene)|ensembl:ENSG00000234495(gene)|ensembl:ENSG00000237071(gene)|ensembl:ENST00000377199(transcript)|ensembl:ENST00000400720(transcript)|ensembl:ENST00000431123(transcript)|ensembl:ENST00000435528(transcript)|ensembl:ENST00000437160(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001650"(fibrillar center)|go:"GO:0002820"(negative regulation of adaptive immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)	refseq:NP_014670.1|sgd:S000005553|ensemblfungi:YOR027W(gene)|ensemblfungi:YOR027W_mRNA(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0008104"(protein localization)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0042030"(ATPase inhibitor activity)|go:"GO:0051879"(Hsp90 protein binding)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR041243|rcsb pdb:2LLV|rcsb pdb:2LLW|rcsb pdb:3UPV|rcsb pdb:3UQ3|reactome:R-SCE-3371497|reactome:R-SCE-9696273|dip:DIP-2329N|mint:P15705	-	-	crc64:CF8A85C2BBD3C44C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:dsfH5OUghD8KSaTz1SFw9OYVTK49606	rogid:+w2ibiXXPwvtcC3RxknGi0ELvvE559292	intact-crc:2FDD05B99545369C|rigid:/0f+kHMDtL8MhCjXJzxLlnLTMwo	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P18961	uniprotkb:O00444	intact:EBI-29484|uniprotkb:D6VZS6|ensemblfungi:YMR104C	intact:EBI-746202|uniprotkb:Q8IYF0|uniprotkb:Q96Q95|uniprotkb:B2RAL0|uniprotkb:B7Z837|uniprotkb:B7Z8G7|uniprotkb:Q9UD84|uniprotkb:Q9UDE2|ensembl:ENSP00000270861	psi-mi:ypk2_yeast(display_long)|uniprotkb:YPK2(gene name)|psi-mi:YPK2(display_short)|uniprotkb:YKR2(gene name synonym)|uniprotkb:YMR104C(locus name)|uniprotkb:YM9718.03C(orf name)	psi-mi:plk4_human(display_long)|uniprotkb:Polo-like kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase Sak(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 18(gene name synonym)|uniprotkb:PLK4(gene name)|psi-mi:PLK4(display_short)|uniprotkb:SAK(gene name synonym)|uniprotkb:STK18(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11548944|imex:IM-24995-2807	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013822.1|sgd:S000004710|dip:DIP-4438N|mint:P18961|ensemblfungi:YMR104C(gene)|ensemblfungi:YMR104C_mRNA(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0060237"(regulation of fungal-type cell wall organization)|go:"GO:0070941"(eisosome assembly)|go:"GO:0071555"(cell wall organization)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892	refseq:NP_001177728.1|refseq:NP_001177730.1|refseq:NP_055079.3|dip:DIP-34467N|rcsb pdb:5LHZ|rcsb pdb:6N45|rcsb pdb:6N46|rcsb pdb:6W38|rcsb pdb:6W3I|rcsb pdb:6W3J|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|rcsb pdb:5LHY|reactome:R-HSA-5620912|reactome:R-HSA-8854518|ensembl:ENSG00000142731(gene)|ensembl:ENST00000270861(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0001741"(XY body)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007099"(centriole replication)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0046601"(positive regulation of centriole replication)|go:"GO:0060271"(cilium assembly)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0098535"(de novo centriole assembly involved in multi-ciliated epithelial cell differentiation)|go:"GO:0098536"(deuterosome)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033696|interpro:IPR033698|interpro:IPR033699|interpro:IPR033700|mint:O00444|rcsb pdb:2N19|rcsb pdb:3COK|rcsb pdb:4JXF|rcsb pdb:4N7V|rcsb pdb:4N7Z|rcsb pdb:4N9J|rcsb pdb:4YUR|rcsb pdb:4YYP	-	crc64:E1FAB0295386A113	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:wDHCJlSmOMy9MWExwxHzLA4+dO0559292	rogid:xqjVEnoGXDk/+2AzLRAkyPK80OI9606	intact-crc:87F9498ACF4A9068|rigid:t8IsHTPshCST0iHthikEDRrlCys	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P17695	uniprotkb:O43765	intact:EBI-7699|uniprotkb:Q6B234|uniprotkb:D6VTD4|ensemblfungi:YDR513W	intact:EBI-347996|ensembl:ENSP00000221566|ensembl:ENSP00000503397|ensembl:ENSP00000504495|uniprotkb:Q9BTZ9|intact:EBI-1045243|uniprotkb:Q6FIA9|uniprotkb:D6W610	psi-mi:glrx2_yeast(display_long)|uniprotkb:TTR(gene name synonym)|uniprotkb:GRX2(gene name)|psi-mi:GRX2(display_short)|uniprotkb:Thioltransferase(gene name synonym)|uniprotkb:Glutathione-dependent oxidoreductase 2(gene name synonym)|uniprotkb:TTR1(gene name synonym)|uniprotkb:D9719.17(orf name)|uniprotkb:YDR513W(locus name)	psi-mi:sgta_human(display_long)|uniprotkb:SGTA(gene name)|psi-mi:SGTA(display_short)|uniprotkb:SGT(gene name synonym)|uniprotkb:Alpha-SGT(gene name synonym)|uniprotkb:Vpu-binding protein(gene name synonym)|uniprotkb:SGT1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11548940|imex:IM-24995-2806	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010801.1|sgd:S000002921|dip:DIP-5271N|ensemblfungi:YDR513W(gene)|ensemblfungi:YDR513W_mRNA(transcript)|go:"GO:0004362"("glutathione-disulfide reductase (NADPH) activity")|go:"GO:0004364"(glutathione transferase activity)|go:"GO:0004602"(glutathione peroxidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0015036"(disulfide oxidoreductase activity)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0097573"(glutathione oxidoreductase activity)|interpro:IPR002109(Glutaredoxin)|interpro:IPR011767(Glutaredoxin active site)|interpro:IPR011899(Glutaredoxin, eukaryotic and viruses)|interpro:IPR014025(Glutaredoxin subgroup)|interpro:IPR036249|rcsb pdb:3CTF|rcsb pdb:3CTG|rcsb pdb:3D4M|rcsb pdb:3D5J	rcsb pdb:4CPG|rcsb pdb:4GOD|rcsb pdb:4GOE|rcsb pdb:4GOF|reactome:R-HSA-9609523|rcsb pdb:2VYI|ensembl:ENSG00000104969(gene)|ensembl:ENST00000221566(transcript)|ensembl:ENST00000676943(transcript)|ensembl:ENST00000677149(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072380"(TRC complex)|go:"GO:0098850"(extrinsic component of synaptic vesicle membrane)|go:"GO:1903070"(negative regulation of ER-associated ubiquitin-dependent protein catabolic process)|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)|go:"GO:1903646"(positive regulation of chaperone-mediated protein folding)|go:"GO:1904288"(BAT3 complex binding)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR032374|mint:O43765|refseq:XP_011526480.1|refseq:NP_003012.1	-	crc64:99A79B87695B2266	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:u4CcRMaG3tJhhzqf3yNKktvKfv4559292	rogid:r/Cyj4UJk/cS8QdrbjhTZMPCigI9606	intact-crc:6D3FFC6A864B45C4|rigid:UrLJNS0V1U9lTAQcdJO0Z/NX+X0	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P17157	uniprotkb:Q08379	intact:EBI-13327|uniprotkb:Q03089|uniprotkb:Q06888|ensemblfungi:YPL031C|uniprotkb:D6W3Y2	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	psi-mi:pho85_yeast(display_long)|uniprotkb:PHO85(gene name)|psi-mi:PHO85(display_short)|uniprotkb:SSG3(gene name synonym)|uniprotkb:P7102.18A(orf name)|uniprotkb:Serine/threonine-protein kinase PHO85(gene name synonym)|uniprotkb:Negative regulator of the PHO system(gene name synonym)|uniprotkb:YPL031C(locus name)	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11548928|imex:IM-24995-2803	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015294.1|sgd:S000005952|ensemblfungi:YPL031C(gene)|ensemblfungi:YPL031C_mRNA(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016242"(negative regulation of macroautophagy)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032878"(regulation of establishment or maintenance of cell polarity)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045719"(negative regulation of glycogen biosynthetic process)|go:"GO:0045936"(negative regulation of phosphate metabolic process)|go:"GO:0046822"(regulation of nucleocytoplasmic transport)|go:"GO:0050849"(negative regulation of calcium-mediated signaling)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0005737"(cytoplasm)|rcsb pdb:2PK9|rcsb pdb:2PMI|rcsb pdb:4KRC|rcsb pdb:4KRD|go:"GO:0005634"(nucleus)|go:"GO:0071073"(positive regulation of phospholipid biosynthetic process)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901987"(regulation of cell cycle phase transition)|go:"GO:1990860"(Pho85-Pho80 CDK-cyclin complex)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P17157|dip:DIP-1493N	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N	-	crc64:246A4358870B00EC	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2017/05/26	rogid:hrRlpgrzGGTT3/GQ5x0LgsjaGeE559292	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	intact-crc:D812F7947EA6CF85|rigid:yhUw4ej2ECe4hzP0ttntGIKK+bM	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P17214	intact:EBI-11523568	intact:EBI-6684|uniprotkb:Q05997|uniprotkb:D6VYN3|ensemblfungi:YLR233C	-	psi-mi:est1_yeast(display_long)|uniprotkb:EST1(gene name)|psi-mi:EST1(display_short)|uniprotkb:YLR233C(locus name)|uniprotkb:L8083.15(orf name)|uniprotkb:Ever shorter telomeres protein 1(gene name synonym)	psi-mi:nav2(display_short)|psi-mi:EBI-11523568(display_long)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11548932|imex:IM-24995-2804	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013334.1|sgd:S000004223|reactome:R-SCE-975957|dip:DIP-1306N|ensemblfungi:YLR233C(gene)|ensemblfungi:YLR233C_mRNA(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005730"(nucleolus)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0032210"(regulation of telomere maintenance via telomerase)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0071919"(G-quadruplex DNA formation)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR018834|interpro:IPR019458	-	-	crc64:9CF552AFDA6BDEDE	no-uniprot-update:	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:hu3SMHhlU1yKF9bVHdYQucREmxQ559292	rogid:WyH5VrQlZ4x7Sr5Hd4ApJ74qrL49606	intact-crc:C0A00ABD5EAAC8D9|rigid:J1SSoGLyVpnh58nSouQ0nL7cFuk	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P17214	uniprotkb:O14641	intact:EBI-6684|uniprotkb:Q05997|uniprotkb:D6VYN3|ensemblfungi:YLR233C	intact:EBI-740850|ensembl:ENSP00000005340|uniprotkb:Q53XM0|uniprotkb:D3DTN3	psi-mi:est1_yeast(display_long)|uniprotkb:EST1(gene name)|psi-mi:EST1(display_short)|uniprotkb:YLR233C(locus name)|uniprotkb:L8083.15(orf name)|uniprotkb:Ever shorter telomeres protein 1(gene name synonym)	psi-mi:dvl2_human(display_long)|uniprotkb:DSH homolog 2(gene name synonym)|uniprotkb:DVL2(gene name)|psi-mi:DVL2(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11548936|imex:IM-24995-2805	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013334.1|sgd:S000004223|reactome:R-SCE-975957|dip:DIP-1306N|ensemblfungi:YLR233C(gene)|ensemblfungi:YLR233C_mRNA(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005730"(nucleolus)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0032210"(regulation of telomere maintenance via telomerase)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0071919"(G-quadruplex DNA formation)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR018834|interpro:IPR019458	refseq:NP_004413.1|ensembl:ENSG00000004975(gene)|ensembl:ENST00000005340(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005109"(frizzled binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0007507"(heart development)|go:"GO:0016235"(aggresome)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044340"(canonical Wnt signaling pathway involved in regulation of cell proliferation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0150012"(positive regulation of neuron projection arborization)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008341(Dishevelled-2 region)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:O14641|rcsb pdb:2REY|rcsb pdb:3CBX|rcsb pdb:3CBY|rcsb pdb:3CBZ|rcsb pdb:3CC0|rcsb pdb:4WIP|rcsb pdb:5LNP|rcsb pdb:5SUY|rcsb pdb:5SUZ|rcsb pdb:6IW3|rcsb pdb:6JCK|reactome:R-HSA-201681|reactome:R-HSA-201688|reactome:R-HSA-2028269|reactome:R-HSA-4086400|reactome:R-HSA-4608870|reactome:R-HSA-4641258|reactome:R-HSA-4641262|reactome:R-HSA-5099900|reactome:R-HSA-5368598|reactome:R-HSA-5663220|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9673324|ensembl:ENSP00000005340|dip:DIP-34433N	-	crc64:9CF552AFDA6BDEDE	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:hu3SMHhlU1yKF9bVHdYQucREmxQ559292	rogid:2Vdc8oRnT4Mz/j+EXQXrL3AszOc9606	intact-crc:DE6B59082E967C30|rigid:mkiA782rXN9MsNLHSrz90WSvBRE	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8N5R6	uniprotkb:P20053	intact:EBI-740841|intact:EBI-953781|uniprotkb:B3KQ49|uniprotkb:A8K3U4|uniprotkb:A8MPQ6|uniprotkb:A8MV61|uniprotkb:A8MVU9|uniprotkb:Q9H5Q6|uniprotkb:Q8TAX6|intact:EBI-2320546|intact:EBI-11522976	intact:EBI-219|uniprotkb:D6W4H8|ensemblfungi:YPR178W	psi-mi:ccd33_human(display_long)|uniprotkb:CCDC33(gene name)|psi-mi:CCDC33(display_short)|uniprotkb:Cancer/testis antigen 61(gene name synonym)	psi-mi:prp4_yeast(display_long)|uniprotkb:PRP4(gene name)|psi-mi:PRP4(display_short)|uniprotkb:RNA4(gene name synonym)|uniprotkb:YPR178W(locus name)|uniprotkb:P9705.6(orf name)|uniprotkb:Pre-mRNA-processing protein 4(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11548964|imex:IM-24995-2812	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_079331.3|interpro:IPR000008(C2 calcium-dependent membrane targeting)|go:"GO:0005777"(peroxisome)|refseq:NP_001274110.1|refseq:NP_877592.2|mint:Q8N5R6|interpro:IPR035892|interpro:IPR039889	refseq:NP_015504.1|sgd:S000006382|mint:P20053|dip:DIP-2607N|ensemblfungi:YPR178W(gene)|ensemblfungi:YPR178W_mRNA(transcript)|go:"GO:0000393"(spliceosomal conformational changes to generate catalytic conformation)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0030621"(U4 snRNA binding)|go:"GO:0034247"(snoRNA splicing)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR014906("Pre-mRNA processing factor 4 (PRP4) like")|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|rcsb pdb:3JCM|rcsb pdb:5GAN|rcsb pdb:5GAP|rcsb pdb:5NRL|rcsb pdb:5ZWM|rcsb pdb:5ZWO	-	-	crc64:7CCCA3A92AC0CE78	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2021/11/30	rogid:eEIn7pQyfdHWx8TeLJpYy0i/gww9606	rogid:vvz5G0rqqyrugTvAPelDKit9FpQ559292	intact-crc:841BBABD5E7A0A15|rigid:ptA+Hsnjl/Y0xmHa4k1KOheQruE	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:A0A024R0Y4	uniprotkb:P20053	intact:EBI-11523730|ensembl:ENSP00000477709|ensembl:ENSP00000478363|ensembl:ENSP00000481091	intact:EBI-219|uniprotkb:D6W4H8|ensemblfungi:YPR178W	psi-mi:a0a024r0y4_human(display_long)|uniprotkb:TADA2A(gene name)|psi-mi:TADA2A(display_short)|uniprotkb:TADA2L(gene name synonym)|uniprotkb:hCG_28187(orf name)	psi-mi:prp4_yeast(display_long)|uniprotkb:PRP4(gene name)|psi-mi:PRP4(display_short)|uniprotkb:RNA4(gene name synonym)|uniprotkb:YPR178W(locus name)|uniprotkb:P9705.6(orf name)|uniprotkb:Pre-mRNA-processing protein 4(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11548960|imex:IM-24995-2811	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001159577.2|refseq:NP_001479.4|ensembl:ENSG00000276234(gene)|ensembl:ENST00000612272(transcript)|ensembl:ENST00000615182(transcript)|ensembl:ENST00000620628(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031063"(regulation of histone deacetylation)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0035065"(regulation of histone acetylation)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090043"(regulation of tubulin deacetylation)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016827(Transcriptional adaptor 2)|interpro:IPR017884|interpro:IPR017930|interpro:IPR036388|interpro:IPR041983|interpro:IPR043145	refseq:NP_015504.1|sgd:S000006382|mint:P20053|dip:DIP-2607N|ensemblfungi:YPR178W(gene)|ensemblfungi:YPR178W_mRNA(transcript)|go:"GO:0000393"(spliceosomal conformational changes to generate catalytic conformation)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0030621"(U4 snRNA binding)|go:"GO:0034247"(snoRNA splicing)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR014906("Pre-mRNA processing factor 4 (PRP4) like")|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|rcsb pdb:3JCM|rcsb pdb:5GAN|rcsb pdb:5GAP|rcsb pdb:5NRL|rcsb pdb:5ZWM|rcsb pdb:5ZWO	-	-	crc64:7CCCA3A92AC0CE78	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:IGh7vC68gMLe+tAVGM4gc0rzc6Y9606	rogid:vvz5G0rqqyrugTvAPelDKit9FpQ559292	intact-crc:C68467F9FFD2C9EA|rigid:OC6yQLt062fWuC2VxG3k80O5t54	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P18961	uniprotkb:Q8N5R6	intact:EBI-29484|uniprotkb:D6VZS6|ensemblfungi:YMR104C	intact:EBI-740841|intact:EBI-953781|uniprotkb:B3KQ49|uniprotkb:A8K3U4|uniprotkb:A8MPQ6|uniprotkb:A8MV61|uniprotkb:A8MVU9|uniprotkb:Q9H5Q6|uniprotkb:Q8TAX6|intact:EBI-2320546|intact:EBI-11522976	psi-mi:ypk2_yeast(display_long)|uniprotkb:YPK2(gene name)|psi-mi:YPK2(display_short)|uniprotkb:YKR2(gene name synonym)|uniprotkb:YMR104C(locus name)|uniprotkb:YM9718.03C(orf name)	psi-mi:ccd33_human(display_long)|uniprotkb:CCDC33(gene name)|psi-mi:CCDC33(display_short)|uniprotkb:Cancer/testis antigen 61(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11548948|imex:IM-24995-2808	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013822.1|sgd:S000004710|dip:DIP-4438N|mint:P18961|ensemblfungi:YMR104C(gene)|ensemblfungi:YMR104C_mRNA(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0060237"(regulation of fungal-type cell wall organization)|go:"GO:0070941"(eisosome assembly)|go:"GO:0071555"(cell wall organization)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892	refseq:NP_079331.3|interpro:IPR000008(C2 calcium-dependent membrane targeting)|go:"GO:0005777"(peroxisome)|refseq:NP_001274110.1|refseq:NP_877592.2|mint:Q8N5R6|interpro:IPR035892|interpro:IPR039889	-	crc64:E1FAB0295386A113	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2021/11/30	rogid:wDHCJlSmOMy9MWExwxHzLA4+dO0559292	rogid:eEIn7pQyfdHWx8TeLJpYy0i/gww9606	intact-crc:AE7AA375D4576E2A|rigid:G9G1d64MxZogkpe+g+zrI4doMs4	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P20049	uniprotkb:O75928-2	intact:EBI-19686|uniprotkb:D6VQG2|ensemblfungi:YBR166C	intact:EBI-348567|ensembl:ENSP00000317163|intact:EBI-7259183|intact:MINT-1455402	psi-mi:tyr1_yeast(display_long)|uniprotkb:TYR1(gene name)|psi-mi:TYR1(display_short)|uniprotkb:YBR1218(orf name)|uniprotkb:YBR166C(locus name)	psi-mi:o75928-2(display_long)|uniprotkb:Msx-interacting zinc finger protein(gene name synonym)|uniprotkb:PIAS-NY protein(gene name synonym)|uniprotkb:Protein inhibitor of activated STAT x(gene name synonym)|uniprotkb:Protein inhibitor of activated STAT2(gene name synonym)|uniprotkb:PIAS2(gene name)|psi-mi:PIAS2(display_short)|uniprotkb:PIASX(gene name synonym)|uniprotkb:Androgen receptor-interacting protein 3(gene name synonym)|uniprotkb:DAB2-interacting protein(gene name synonym)|uniprotkb:PIASx-alpha(isoform synonym)|uniprotkb:ARIP3(isoform synonym)|uniprotkb:E3 SUMO-protein transferase PIAS2(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11548952|imex:IM-24995-2809	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009725.1|sgd:S000000370|ensemblfungi:YBR166C(gene)|ensemblfungi:YBR166C_mRNA(transcript)|go:"GO:0004665"("prephenate dehydrogenase (NADP+) activity")|go:"GO:0005737"(cytoplasm)|go:"GO:0006570"(tyrosine metabolic process)|go:"GO:0006571"(tyrosine biosynthetic process)|go:"GO:0008652"(cellular amino acid biosynthetic process)|go:"GO:0008977"("prephenate dehydrogenase (NAD+) activity")|go:"GO:0070403"(NAD+ binding)|interpro:IPR003099(Prephenate dehydrogenase)|interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|interpro:IPR012385(Prephenate dehydrogenase, fungal)|interpro:IPR036291|dip:DIP-4627N|mint:P20049	intact:EBI-348555(pias2_human)|ensembl:ENSG00000078043(gene)|ensembl:ENST00000324794(transcript)|uniprotkb:O75928-2(isoform-parent)	-	crc64:D483B93ABBC8F8F4	isoform-comment:"Contains a glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) at position 562."	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:tqskEEcG2cewNJk/xHHqihVa8ss559292	rogid:JNC3UGf8YuVcrXbFnO27d4orf4I9606	intact-crc:84255E950FA12260|rigid:GzTNSfB4U5rOKiODhLM8nL6bcyY	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P14373	uniprotkb:P20053	intact:EBI-719493|uniprotkb:A2BE15|uniprotkb:Q5RJA8|uniprotkb:Q5ST26|uniprotkb:Q6LA73|uniprotkb:Q6NXR9|uniprotkb:Q9BZY6|uniprotkb:Q9UJL3|ensembl:ENSP00000383555|ensembl:ENSP00000392787|ensembl:ENSP00000405229|ensembl:ENSP00000414793|ensembl:ENSP00000366404	intact:EBI-219|uniprotkb:D6W4H8|ensemblfungi:YPR178W	psi-mi:tri27_human(display_long)|uniprotkb:TRIM27(gene name)|psi-mi:TRIM27(display_short)|uniprotkb:RNF76(gene name synonym)|uniprotkb:RFP(gene name synonym)|uniprotkb:Ret finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 27(gene name synonym)|uniprotkb:RING finger protein 76(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM27(gene name synonym)	psi-mi:prp4_yeast(display_long)|uniprotkb:PRP4(gene name)|psi-mi:PRP4(display_short)|uniprotkb:RNA4(gene name synonym)|uniprotkb:YPR178W(locus name)|uniprotkb:P9705.6(orf name)|uniprotkb:Pre-mRNA-processing protein 4(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11548956|imex:IM-24995-2810	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006501.1|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0090281"(negative regulation of calcium ion import)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR020457|interpro:IPR035791|interpro:IPR043136|mint:P14373|reactome:R-HSA-3232142|reactome:R-HSA-9635465|reactome:R-HSA-8948751|ensembl:ENSG00000204713(gene)|ensembl:ENSG00000215641(gene)|ensembl:ENSG00000229006(gene)|ensembl:ENSG00000234495(gene)|ensembl:ENSG00000237071(gene)|ensembl:ENST00000377199(transcript)|ensembl:ENST00000400720(transcript)|ensembl:ENST00000431123(transcript)|ensembl:ENST00000435528(transcript)|ensembl:ENST00000437160(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001650"(fibrillar center)|go:"GO:0002820"(negative regulation of adaptive immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)	refseq:NP_015504.1|sgd:S000006382|mint:P20053|dip:DIP-2607N|ensemblfungi:YPR178W(gene)|ensemblfungi:YPR178W_mRNA(transcript)|go:"GO:0000393"(spliceosomal conformational changes to generate catalytic conformation)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0030621"(U4 snRNA binding)|go:"GO:0034247"(snoRNA splicing)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR014906("Pre-mRNA processing factor 4 (PRP4) like")|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|rcsb pdb:3JCM|rcsb pdb:5GAN|rcsb pdb:5GAP|rcsb pdb:5NRL|rcsb pdb:5ZWM|rcsb pdb:5ZWO	-	-	crc64:7CCCA3A92AC0CE78	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:dsfH5OUghD8KSaTz1SFw9OYVTK49606	rogid:vvz5G0rqqyrugTvAPelDKit9FpQ559292	intact-crc:9C83A701A06EB68E|rigid:POgDzDouQfkuac4iSySiCK+tyQ8	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P21734	uniprotkb:O95376	intact:EBI-19717|uniprotkb:D6VSF9|ensemblfungi:YDR177W	intact:EBI-711158|uniprotkb:Q9HBZ6|uniprotkb:Q9UEM9|ensembl:ENSP00000348769|ensembl:ENSP00000403222	psi-mi:ubc1_yeast(display_long)|uniprotkb:UBC1(gene name)|psi-mi:UBC1(display_short)|uniprotkb:YDR177W(locus name)|uniprotkb:YD9395.10(orf name)|uniprotkb:Ubiquitin-protein ligase(gene name synonym)|uniprotkb:Ubiquitin carrier protein(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-24 kDa(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme 1(gene name synonym)	psi-mi:ari2_human(display_long)|uniprotkb:Triad1 protein(gene name synonym)|uniprotkb:ARIH2(gene name)|psi-mi:ARIH2(display_short)|uniprotkb:ARI2(gene name synonym)|uniprotkb:TRIAD1(gene name synonym)|uniprotkb:HT005(orf name)|uniprotkb:RING-type E3 ubiquitin transferase ARIH2(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11548984|imex:IM-24995-2817	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002584|ensemblfungi:YDR177W(gene)|ensemblfungi:YDR177W_mRNA(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016050"(vesicle organization)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070628"(proteasome binding)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR009060(UBA-like)|interpro:IPR015368(Ubiquitin-conjugating enzyme, C-terminal fungi)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1FXT|rcsb pdb:1FZY|rcsb pdb:1TTE|reactome:R-SCE-8866652|reactome:R-SCE-983168|refseq:NP_010462.3|dip:DIP-6594N|mint:P21734	refseq:NP_001304262.1|refseq:NP_001304263.1|refseq:NP_006312.1|ensembl:ENSG00000177479(gene)|ensembl:ENST00000356401(transcript)|ensembl:ENST00000449376(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0048588"(developmental cell growth)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0071425"(hematopoietic stem cell proliferation)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002867(Zinc finger, C6HC-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR031126|interpro:IPR031127|interpro:IPR044066|reactome:R-HSA-983168|refseq:XP_016861020.1|refseq:XP_016861021.1	-	crc64:899CC397A1285145	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:3N1WHZJcgMeK0OglGpGI2m4XU8Q559292	rogid:536Qu2bpbptYcIhxoeLJNTErLTM9606	intact-crc:B7C98E2FF9D2473C|rigid:j7z9megFLIB4albVuagtbf0OQ80	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q08379	uniprotkb:P20676	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	intact:EBI-12392|ensemblfungi:YOR098C|uniprotkb:D6W2F9	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:nup1_yeast(display_long)|uniprotkb:NUP1(gene name)|psi-mi:NUP1(display_short)|uniprotkb:YOR098C(locus name)|uniprotkb:YOR3182C(orf name)|uniprotkb:Nuclear pore protein NUP1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11548980|imex:IM-24995-2816	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N	ensemblfungi:YOR098C(gene)|ensemblfungi:YOR098C_mRNA(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000972"(transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0005643"(nuclear pore)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0044615"(nuclear pore nuclear basket)|interpro:IPR026054|rcsb pdb:4C31|rcsb pdb:4MBE|rcsb pdb:5OWU|go:"GO:0006607"(NLS-bearing protein import into nucleus)|refseq:NP_014741.1|sgd:S000005624|mint:P20676|dip:DIP-81N	-	-	crc64:4AC23567D2FB53CC	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2017/05/26	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	rogid:X1AjTIzoXjQ7vXlKzI88m7xfu6w559292	intact-crc:8530E1219DB4D9DA|rigid:NiqQjTaP3EVF+eZ72FYDbdhmnC8	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O43186	uniprotkb:P20053	intact:EBI-748171|uniprotkb:Q0QD45|ensembl:ENSP00000221996|ensembl:ENSP00000445565	intact:EBI-219|uniprotkb:D6W4H8|ensemblfungi:YPR178W	psi-mi:crx_human(display_long)|uniprotkb:CRX(gene name)|psi-mi:CRX(display_short)|uniprotkb:CORD2(gene name synonym)	psi-mi:prp4_yeast(display_long)|uniprotkb:PRP4(gene name)|psi-mi:PRP4(display_short)|uniprotkb:RNA4(gene name synonym)|uniprotkb:YPR178W(locus name)|uniprotkb:P9705.6(orf name)|uniprotkb:Pre-mRNA-processing protein 4(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11548968|imex:IM-24995-2813	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000545.1|ensembl:ENSG00000105392(gene)|ensembl:ENST00000221996(transcript)|ensembl:ENST00000539067(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007601"(visual perception)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050896"(response to stimulus)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013851(Transcription factor Otx, C-terminal)|interpro:IPR017970	refseq:NP_015504.1|sgd:S000006382|mint:P20053|dip:DIP-2607N|ensemblfungi:YPR178W(gene)|ensemblfungi:YPR178W_mRNA(transcript)|go:"GO:0000393"(spliceosomal conformational changes to generate catalytic conformation)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0030621"(U4 snRNA binding)|go:"GO:0034247"(snoRNA splicing)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR014906("Pre-mRNA processing factor 4 (PRP4) like")|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|rcsb pdb:3JCM|rcsb pdb:5GAN|rcsb pdb:5GAP|rcsb pdb:5NRL|rcsb pdb:5ZWM|rcsb pdb:5ZWO	-	-	crc64:7CCCA3A92AC0CE78	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:v/bkO/0iLzq1Q2HtieWQQ40RF9M9606	rogid:vvz5G0rqqyrugTvAPelDKit9FpQ559292	intact-crc:E518B515BD7D0161|rigid:5xdYT8xK3b48eAEKcfSQjFxSIxw	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:A0A0C4DGF1	uniprotkb:P20081	intact:EBI-10188476|ensembl:ENSP00000433657	intact:EBI-6961|uniprotkb:D6W147|ensemblfungi:YNL135C	psi-mi:a0a0c4dgf1_human(display_long)|uniprotkb:ZBTB32(gene name)|psi-mi:ZBTB32(display_short)	psi-mi:fkbp_yeast(display_long)|uniprotkb:RBP1(gene name synonym)|uniprotkb:N1213(orf name)|uniprotkb:N1845(orf name)|uniprotkb:YNL135C(locus name)|uniprotkb:FPR1(gene name)|psi-mi:FPR1(display_short)|uniprotkb:FKB1(gene name synonym)|uniprotkb:Peptidyl-prolyl cis-trans isomerase(gene name synonym)|uniprotkb:Rapamycin-binding protein(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11548972|imex:IM-24995-2814	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|ensembl:ENSG00000011590(gene)|ensembl:ENST00000481182(transcript)|go:"GO:0042802"(identical protein binding)	refseq:NP_014264.1|sgd:S000005079|dip:DIP-1263N|mint:P20081|ensemblfungi:YNL135C(gene)|ensemblfungi:YNL135C_mRNA(transcript)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005527"(macrolide binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006325"(chromatin organization)|go:"GO:0006457"(protein folding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:1901710"(regulation of homoserine biosynthetic process)|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)|rcsb pdb:1YAT	-	-	crc64:65C134830D300C06	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:w3k7YT4kw/T+Xi5YBqGHSpHtwMM9606	rogid:8afvGSk+mPghtqkVoWd2rHJXXhQ559292	intact-crc:377170FB95E5BE5A|rigid:aH70cUocyuJplPpMqCt6QIeja2w	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
intact:EBI-11523890	uniprotkb:P20107	-	intact:EBI-29667|uniprotkb:D6W070|ensemblfungi:YMR243C	psi-mi:a0a087wwc3_human(display_short)|psi-mi:EBI-11523890(display_long)|uniprotkb:PDCL2(gene name)|psi-mi:PDCL2(display_short)	psi-mi:zrc1_yeast(display_long)|uniprotkb:ZRC1(gene name)|psi-mi:ZRC1(display_short)|uniprotkb:YM9408.05C(orf name)|uniprotkb:YMR243C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11548976|imex:IM-24995-2815	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:A0A087WWC3(uniprot-removed-ac)	refseq:NP_013970.1|sgd:S000004856|dip:DIP-2030N|mint:P20107|ensemblfungi:YMR243C(gene)|ensemblfungi:YMR243C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005385"(zinc ion transmembrane transporter activity)|go:"GO:0006882"(cellular zinc ion homeostasis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0071577"(zinc ion transmembrane transport)|interpro:IPR002524(Cation efflux protein)|interpro:IPR027469|interpro:IPR036837|reactome:R-SCE-425410|reactome:R-SCE-435368	-	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:vhktqKnu+qJ9+neTG7Pkfxd3rG49606	rogid:ZZlCJ2Xj5Hiumdl3BNStZFS9qM4559292	intact-crc:8FB13D0CF31EAA8E|rigid:TdKuORqOHMmkfsvl18iHcBjb19M	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O15156-2	uniprotkb:P25343	intact:EBI-11522250|ensembl:ENSP00000406286	intact:EBI-14490|uniprotkb:D6VR18|ensemblfungi:YCR009C	psi-mi:o15156-2(display_long)|uniprotkb:ZBTB7B(gene name)|psi-mi:ZBTB7B(display_short)|uniprotkb:Krueppel-related zinc finger protein cKrox(gene name synonym)|uniprotkb:T-helper-inducing POZ/Krueppel-like factor(gene name synonym)|uniprotkb:ZBTB15(gene name synonym)|uniprotkb:ZFP67(gene name synonym)|uniprotkb:ZNF857B(gene name synonym)|uniprotkb:Zinc finger and BTB domain-containing protein 15(gene name synonym)|uniprotkb:Zinc finger protein 67 homolog(gene name synonym)|uniprotkb:Zinc finger protein 857B(gene name synonym)|uniprotkb:Zinc finger protein Th-POK(gene name synonym)	psi-mi:rv161_yeast(display_long)|uniprotkb:RVS161(gene name)|psi-mi:RVS161(display_short)|uniprotkb:END6(gene name synonym)|uniprotkb:SPE161(gene name synonym)|uniprotkb:YCR009C(locus name)|uniprotkb:YCR9C(orf name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549004|imex:IM-24995-2822	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-740434(isoform-parent)|ensembl:ENSG00000160685(gene)|ensembl:ENST00000417934(transcript)|uniprotkb:O15156-2(isoform-parent)	ensemblfungi:YCR009C(gene)|ensemblfungi:YCR009C_mRNA(transcript)|go:"GO:0000747"(conjugation with cellular fusion)|go:"GO:0005829"(cytosol)|go:"GO:0005937"(mating projection)|go:"GO:0006897"(endocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030479"(actin cortical patch)|go:"GO:0031097"(medial cortex)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0042594"(response to starvation)|go:"GO:0043332"(mating projection tip)|go:"GO:0045121"(membrane raft)|go:"GO:0051666"(actin cortical patch localization)|go:"GO:0060988"(lipid tube assembly)|go:"GO:0097320"(plasma membrane tubulation)|go:"GO:1990528"(Rvs161p-Rvs167p complex)|interpro:IPR004148(BAR)|interpro:IPR027267|go:"GO:0006970"(response to osmotic stress)|interpro:IPR037429|refseq:NP_009935.1|sgd:S000000602|mint:P25343|dip:DIP-1601N	-	isoform-comment:No experimental confirmation available.	crc64:B35EA00E0C900E2D	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:41NEFYyprTXI+fOHVFh78TPKF289606	rogid:IdjO8RS5vcYMeGxuoPoa/5e7QJQ559292	intact-crc:68343AB31EFC4BFF|rigid:gM6N97nvBxr3+9i2/GfwyjGQenQ	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O15217	uniprotkb:P25335	intact:EBI-752440|uniprotkb:Q5T7Q8|uniprotkb:Q9BX18|uniprotkb:Q9H414|uniprotkb:B2RD15|uniprotkb:Q6P4G1|ensembl:ENSP00000359998|ensembl:ENSP00000360002	intact:EBI-2442|uniprotkb:D6VVW0|ensemblfungi:YIR029W	psi-mi:gsta4_human(display_long)|uniprotkb:Glutathione S-transferase A4-4(gene name synonym)|uniprotkb:GST class-alpha member 4(gene name synonym)|uniprotkb:GSTA4(gene name)|psi-mi:GSTA4(display_short)	psi-mi:allc_yeast(display_long)|uniprotkb:DAL2(gene name)|psi-mi:DAL2(display_short)|uniprotkb:ALC1(gene name synonym)|uniprotkb:Allantoate amidinohydrolase(gene name synonym)|uniprotkb:YIR029W(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549000|imex:IM-24995-2821	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001503.1|refseq:XP_005249092.1|ensembl:ENSG00000170899(gene)|ensembl:ENST00000370959(transcript)|ensembl:ENST00000370963(transcript)|go:"GO:0004364"(glutathione transferase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0006805"(xenobiotic metabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|interpro:IPR003080(Glutathione S-transferase, alpha class)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR036249|interpro:IPR036282|interpro:IPR040079|rcsb pdb:1GUL|rcsb pdb:1GUM|rcsb pdb:3IK7|reactome:R-HSA-156590	refseq:NP_012295.1|sgd:S000001468|interpro:IPR005164(Allantoicase)|interpro:IPR015908(Allantoicase region)|interpro:IPR008979(Galactose-binding like)|rcsb pdb:1O59|rcsb pdb:1SG3|ensemblfungi:YIR029W(gene)|ensemblfungi:YIR029W_mRNA(transcript)|go:"GO:0000256"(allantoin catabolic process)|go:"GO:0004037"(allantoicase activity)|go:"GO:0006144"(purine nucleobase metabolic process)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:9yVcqmJL64S0kxOW5RJWbOJ25bo9606	rogid:N4TpitQzuAZuemg9Jk458EUQUWc559292	intact-crc:2453B46C03E13F34|rigid:HcrN/v7EspNcIkRwbk4OjqYnRgk	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O95273	uniprotkb:P22354	intact:EBI-748961|uniprotkb:A8K3Q0|uniprotkb:A8K3U2|uniprotkb:Q6ZQN9|uniprotkb:Q7Z519|uniprotkb:Q8NBS7|uniprotkb:Q8NBY2|uniprotkb:Q9NS19|uniprotkb:Q9NYH3|uniprotkb:Q9UHX9|ensembl:ENSP00000300213	intact:EBI-15536|uniprotkb:D6VXE5|ensemblfungi:YKR085C	psi-mi:ccdb1_human(display_long)|uniprotkb:Grap2 and cyclin-D-interacting protein(gene name synonym)|uniprotkb:Human homolog of Maid(gene name synonym)|uniprotkb:CCNDBP1(gene name)|psi-mi:CCNDBP1(display_short)|uniprotkb:DIP1(gene name synonym)|uniprotkb:GCIP(gene name synonym)|uniprotkb:HHM(gene name synonym)	psi-mi:rm20_yeast(display_long)|uniprotkb:MRPL20(gene name)|psi-mi:MRPL20(display_short)|uniprotkb:YKR085C(locus name)|uniprotkb:YKR405(orf name)|uniprotkb:YmL20(gene name synonym)|uniprotkb:Mitochondrial large ribosomal subunit protein mL58(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11548988|imex:IM-24995-2818	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_036274.3|ensembl:ENSG00000166946(gene)|ensembl:ENST00000300213(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0016604"(nuclear body)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR026907|mint:O95273|rcsb pdb:3AY5	refseq:NP_013011.1|sgd:S000001793|rcsb pdb:5MRE|rcsb pdb:5MRF|ensemblfungi:YKR085C(gene)|ensemblfungi:YKR085C_mRNA(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR024388|rcsb pdb:3J6B|rcsb pdb:5MRC|dip:DIP-6793N|mint:P22354	-	-	crc64:3165663C8C19EC60	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:Vi9aoFc+Mov6P3X6KGmsTxXqxvM9606	rogid:DkeQ+P79JhbEGKxUK2g8JXvgBSA559292	intact-crc:CAF3FDF556997762|rigid:PvXhIWJN9xYnvSkM9aLFQuOQjXQ	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P23293	uniprotkb:Q08379	intact:EBI-17078|ensemblfungi:YPR161C|uniprotkb:D6W4G2	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	psi-mi:bur1_yeast(display_long)|uniprotkb:SGV1(gene name)|psi-mi:SGV1(display_short)|uniprotkb:BUR1(gene name synonym)|uniprotkb:YPR161C(locus name)|uniprotkb:P9584.8(orf name)|uniprotkb:Bypass UAS requirement protein 1(gene name synonym)|uniprotkb:Suppressor of GPA1-Vall50 mutation protein 1(gene name synonym)	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11548992|imex:IM-24995-2819	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR011009(Protein kinase-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-SCE-674695|reactome:R-SCE-6796648|reactome:R-SCE-6807505|reactome:R-SCE-75955|reactome:R-SCE-9018519|refseq:NP_015487.1|sgd:S000006365|ensemblfungi:YPR161C(gene)|ensemblfungi:YPR161C_mRNA(transcript)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0030332"(cyclin binding)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|dip:DIP-5916N|mint:P23293	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N	-	crc64:CC9034A4B10A510E	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2017/05/26	rogid:yPWc2VNSXjSxoSgzeiu7Jy5S1C0559292	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	intact-crc:615880450BF34E93|rigid:c8aT+hdlQkCrd4qPTq7qtHXpwp4	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P23497-2	uniprotkb:P12612	intact:EBI-6589365|ensembl:ENSP00000386404	intact:EBI-19045|uniprotkb:D6VSJ6|ensemblfungi:YDR212W	psi-mi:p23497-2(display_long)|uniprotkb:SP100(isoform synonym)|uniprotkb:SP100(gene name)|psi-mi:SP100(display_short)|uniprotkb:Nuclear dot-associated Sp100 protein(gene name synonym)|uniprotkb:Speckled 100 kDa(gene name synonym)|uniprotkb:SP100A(isoform synonym)	psi-mi:tcpa_yeast(display_long)|uniprotkb:TCP1(gene name)|psi-mi:TCP1(display_short)|uniprotkb:CCT1(gene name synonym)|uniprotkb:YDR212W(locus name)|uniprotkb:YD8142.13(orf name)|uniprotkb:YD8142B.04(orf name)|uniprotkb:CCT-alpha(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11548996|imex:IM-24995-2820	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-751145(isoform-parent)|uniprotkb:P23497-2(isoform-parent)|ensembl:ENSG00000067066(gene)|ensembl:ENST00000409341(transcript)	refseq:NP_010498.1|sgd:S000002620|ensemblfungi:YDR212W(gene)|ensemblfungi:YDR212W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012715(T-complex protein 1, alpha subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|rcsb pdb:4V81|rcsb pdb:4V8R|rcsb pdb:4V94|rcsb pdb:5GW4|rcsb pdb:5GW5|rcsb pdb:6KRD|rcsb pdb:6KRE|rcsb pdb:6KS6|rcsb pdb:6KS7|rcsb pdb:6KS8|reactome:R-SCE-390471|reactome:R-SCE-6814122|dip:DIP-2965N|mint:P12612	-	isoform-comment:Major isoform.	crc64:02C625D329359E61	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:HrcogLANB///4vkSYtZ7OtzOb2k9606	rogid:xWMsvY106Y6yQ54SOif2UlScafM559292	intact-crc:025BCB167DD080D0|rigid:b276Sfs8Vc0EZEcpKKwu77YIemc	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O43379	uniprotkb:P25372	intact:EBI-714790|uniprotkb:Q63HP9|uniprotkb:Q659D7|uniprotkb:Q8NBF7|uniprotkb:Q96AD9|intact:EBI-2563293|ensembl:ENSP00000270301	intact:EBI-19616|uniprotkb:D6VR84|ensemblfungi:YCR083W	psi-mi:wdr62_human(display_long)|uniprotkb:WDR62(gene name)|psi-mi:WDR62(display_short)|uniprotkb:C19orf14(gene name synonym)	psi-mi:trx3_yeast(display_long)|uniprotkb:TRX3(gene name)|psi-mi:TRX3(display_short)|uniprotkb:YCR83W(orf name)|uniprotkb:YCR083W(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549024|imex:IM-24995-2827	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007099"(centriole replication)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0022008"(neurogenesis)|go:"GO:0034451"(centriolar satellite)|interpro:IPR001680(WD40 repeat)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR024977|interpro:IPR036322|mint:O43379|go:"GO:0005813"(centrosome)|ensembl:ENSG00000075702(gene)|ensembl:ENST00000270301(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|refseq:NP_001077430.1|refseq:NP_775907.4|refseq:XP_016882154.1|dip:DIP-56792N	interpro:IPR036249|refseq:NP_010006.1|sgd:S000000679|interpro:IPR017937|interpro:IPR013766(Thioredoxin domain)|rcsb pdb:2OE0|rcsb pdb:2OE1|rcsb pdb:2OE3|ensemblfungi:YCR083W(gene)|ensemblfungi:YCR083W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0015036"(disulfide oxidoreductase activity)|go:"GO:0034599"(cellular response to oxidative stress)|rcsb pdb:5YKW	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:bKUivd80luQPFZHsU9mDdwyGwi89606	rogid:g0xjGf9GvJRl8iv2qoT5tOs7jXI559292	intact-crc:C1EBBAA5193BAA3D|rigid:ItU3uRHsL/1Qfpgrmgytvc+ufWg	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O95073-2	uniprotkb:P25372	intact:EBI-10696047	intact:EBI-19616|uniprotkb:D6VR84|ensemblfungi:YCR083W	psi-mi:o95073-2(display_long)|uniprotkb:FSBP(gene name)|psi-mi:FSBP(display_short)	psi-mi:trx3_yeast(display_long)|uniprotkb:TRX3(gene name)|psi-mi:TRX3(display_short)|uniprotkb:YCR83W(orf name)|uniprotkb:YCR083W(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549020|imex:IM-24995-2826	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-1059030(isoform-parent)|uniprotkb:O95073-2(isoform-parent)	interpro:IPR036249|refseq:NP_010006.1|sgd:S000000679|interpro:IPR017937|interpro:IPR013766(Thioredoxin domain)|rcsb pdb:2OE0|rcsb pdb:2OE1|rcsb pdb:2OE3|ensemblfungi:YCR083W(gene)|ensemblfungi:YCR083W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0015036"(disulfide oxidoreductase activity)|go:"GO:0034599"(cellular response to oxidative stress)|rcsb pdb:5YKW	-	isoform-comment:No experimental confirmation available.	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:j4ktleFZa7rAjRFENAKAGdAd+Fs9606	rogid:g0xjGf9GvJRl8iv2qoT5tOs7jXI559292	intact-crc:DD5E980E98F784EE|rigid:pVxgkpSkBuFL5XF5oz/yAWRx/4Y	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P25343	uniprotkb:P14136	intact:EBI-14490|uniprotkb:D6VR18|ensemblfungi:YCR009C	intact:EBI-744302|uniprotkb:Q53H98|uniprotkb:Q5D055|uniprotkb:Q6ZQS3|uniprotkb:Q7Z5J6|uniprotkb:Q7Z5J7|uniprotkb:Q96KS4|uniprotkb:Q96P18|uniprotkb:Q9UFD0|uniprotkb:B2RD44|uniprotkb:D3DX59|intact:EBI-3909365|uniprotkb:E9PAX3|ensembl:ENSP00000466598|uniprotkb:A7REI1	psi-mi:rv161_yeast(display_long)|uniprotkb:RVS161(gene name)|psi-mi:RVS161(display_short)|uniprotkb:END6(gene name synonym)|uniprotkb:SPE161(gene name synonym)|uniprotkb:YCR009C(locus name)|uniprotkb:YCR9C(orf name)	psi-mi:gfap_human(display_long)|uniprotkb:GFAP(gene name)|psi-mi:GFAP(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549008|imex:IM-24995-2823	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YCR009C(gene)|ensemblfungi:YCR009C_mRNA(transcript)|go:"GO:0000747"(conjugation with cellular fusion)|go:"GO:0005829"(cytosol)|go:"GO:0005937"(mating projection)|go:"GO:0006897"(endocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030479"(actin cortical patch)|go:"GO:0031097"(medial cortex)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0042594"(response to starvation)|go:"GO:0043332"(mating projection tip)|go:"GO:0045121"(membrane raft)|go:"GO:0051666"(actin cortical patch localization)|go:"GO:0060988"(lipid tube assembly)|go:"GO:0097320"(plasma membrane tubulation)|go:"GO:1990528"(Rvs161p-Rvs167p complex)|interpro:IPR004148(BAR)|interpro:IPR027267|go:"GO:0006970"(response to osmotic stress)|interpro:IPR037429|refseq:NP_009935.1|sgd:S000000602|mint:P25343|dip:DIP-1601N	refseq:NP_001124491.1|refseq:NP_001229305.1|refseq:NP_002046.1|ensembl:ENSG00000131095(gene)|ensembl:ENST00000588735(transcript)|go:"GO:0005178"(integrin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0009611"(response to wounding)|go:"GO:0010467"(gene expression)|go:"GO:0010625"(positive regulation of Schwann cell proliferation)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0014002"(astrocyte development)|go:"GO:0019900"(kinase binding)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0031102"(neuron projection regeneration)|go:"GO:0042802"(identical protein binding)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0044297"(cell body)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0051580"(regulation of neurotransmitter uptake)|go:"GO:0060020"(Bergmann glial cell differentiation)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0070779"(D-aspartate import across plasma membrane)|go:"GO:0097450"(astrocyte end-foot)|go:"GO:0098574"(cytoplasmic side of lysosomal membrane)|go:"GO:1904714"(regulation of chaperone-mediated autophagy)|interpro:IPR006821(Intermediate filament, DNA-binding region)|interpro:IPR018039|interpro:IPR027701|interpro:IPR039008|mint:P14136|rcsb pdb:6A9P|reactome:R-HSA-1251985|reactome:R-HSA-9613829	-	crc64:B35EA00E0C900E2D	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:IdjO8RS5vcYMeGxuoPoa/5e7QJQ559292	rogid:Pz4JW0WjMjBYILTDSX9jUmMqWhg9606	intact-crc:F4EE05B2970B1421|rigid:WHUjOicWVQnQ5I/yFWGjBsSZtUQ	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
intact:EBI-11524292	uniprotkb:P25372	-	intact:EBI-19616|uniprotkb:D6VR84|ensemblfungi:YCR083W	psi-mi:trip6(display_short)|psi-mi:EBI-11524292(display_long)	psi-mi:trx3_yeast(display_long)|uniprotkb:TRX3(gene name)|psi-mi:TRX3(display_short)|uniprotkb:YCR83W(orf name)|uniprotkb:YCR083W(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549012|imex:IM-24995-2824	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	-	interpro:IPR036249|refseq:NP_010006.1|sgd:S000000679|interpro:IPR017937|interpro:IPR013766(Thioredoxin domain)|rcsb pdb:2OE0|rcsb pdb:2OE1|rcsb pdb:2OE3|ensemblfungi:YCR083W(gene)|ensemblfungi:YCR083W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0015036"(disulfide oxidoreductase activity)|go:"GO:0034599"(cellular response to oxidative stress)|rcsb pdb:5YKW	-	no-uniprot-update:	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:S6W5lkNauGhNejln9bTVoqZjNL49606	rogid:g0xjGf9GvJRl8iv2qoT5tOs7jXI559292	intact-crc:58CFB9D266827D11|rigid:bwExTIDGQGpNGL73rMESgXrHyc0	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P25372	uniprotkb:O14641	intact:EBI-19616|uniprotkb:D6VR84|ensemblfungi:YCR083W	intact:EBI-740850|ensembl:ENSP00000005340|uniprotkb:Q53XM0|uniprotkb:D3DTN3	psi-mi:trx3_yeast(display_long)|uniprotkb:TRX3(gene name)|psi-mi:TRX3(display_short)|uniprotkb:YCR83W(orf name)|uniprotkb:YCR083W(locus name)	psi-mi:dvl2_human(display_long)|uniprotkb:DSH homolog 2(gene name synonym)|uniprotkb:DVL2(gene name)|psi-mi:DVL2(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549016|imex:IM-24995-2825	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR036249|refseq:NP_010006.1|sgd:S000000679|interpro:IPR017937|interpro:IPR013766(Thioredoxin domain)|rcsb pdb:2OE0|rcsb pdb:2OE1|rcsb pdb:2OE3|ensemblfungi:YCR083W(gene)|ensemblfungi:YCR083W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0015036"(disulfide oxidoreductase activity)|go:"GO:0034599"(cellular response to oxidative stress)|rcsb pdb:5YKW	refseq:NP_004413.1|ensembl:ENSG00000004975(gene)|ensembl:ENST00000005340(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005109"(frizzled binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0007507"(heart development)|go:"GO:0016235"(aggresome)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044340"(canonical Wnt signaling pathway involved in regulation of cell proliferation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0150012"(positive regulation of neuron projection arborization)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008341(Dishevelled-2 region)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:O14641|rcsb pdb:2REY|rcsb pdb:3CBX|rcsb pdb:3CBY|rcsb pdb:3CBZ|rcsb pdb:3CC0|rcsb pdb:4WIP|rcsb pdb:5LNP|rcsb pdb:5SUY|rcsb pdb:5SUZ|rcsb pdb:6IW3|rcsb pdb:6JCK|reactome:R-HSA-201681|reactome:R-HSA-201688|reactome:R-HSA-2028269|reactome:R-HSA-4086400|reactome:R-HSA-4608870|reactome:R-HSA-4641258|reactome:R-HSA-4641262|reactome:R-HSA-5099900|reactome:R-HSA-5368598|reactome:R-HSA-5663220|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9673324|ensembl:ENSP00000005340|dip:DIP-34433N	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:g0xjGf9GvJRl8iv2qoT5tOs7jXI559292	rogid:2Vdc8oRnT4Mz/j+EXQXrL3AszOc9606	intact-crc:CB426B0E4AA09B8D|rigid:qW2yYituG07tnqilIn18HK/zMxA	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O76083-2	uniprotkb:P25377	intact:EBI-11524542|ensembl:ENSP00000335242	intact:EBI-2347652|uniprotkb:D6VRA5|ensemblfungi:YCR105W	psi-mi:o76083-2(display_long)|uniprotkb:PDE9A(gene name)|psi-mi:PDE9A(display_short)	psi-mi:adh7_yeast(display_long)|uniprotkb:ADH7(gene name)|psi-mi:ADH7(display_short)|uniprotkb:NADP-dependent alcohol dehydrogenase VII(gene name synonym)|uniprotkb:YCR105W(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549044|imex:IM-24995-2832	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-742764(isoform-parent)|ensembl:ENSG00000160191(gene)|ensembl:ENST00000335512(transcript)|uniprotkb:O76083-2(isoform-parent)	refseq:NP_010030.1|sgd:S000000702|dip:DIP-7661N|mint:P25377|ensemblfungi:YCR105W(gene)|ensemblfungi:YCR105W_mRNA(transcript)|go:"GO:0006066"(alcohol metabolic process)|go:"GO:0008106"("alcohol dehydrogenase (NADP+) activity")|go:"GO:0008270"(zinc ion binding)|go:"GO:0016616"(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|interpro:IPR002328(Alcohol dehydrogenase, zinc-containing, conserved site)|interpro:IPR011032(GroES-like)|interpro:IPR013149(Alcohol dehydrogenase, zinc-binding)|interpro:IPR013154(Alcohol dehydrogenase GroES-like)|interpro:IPR020843|interpro:IPR029752|interpro:IPR036291	-	-	crc64:BFB0E6C5F93D3F07	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:nTzgeYGOwTM/7VJUgxSnlnDiCFo9606	rogid:PGCt+bqhn63vUVgS5IKrrOukXgg559292	intact-crc:531CA7F139ABC942|rigid:JbiTJHJ1iOe/jhMhIOce+Tu0vtY	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P25372	uniprotkb:P19012	intact:EBI-19616|uniprotkb:D6VR84|ensemblfungi:YCR083W	intact:EBI-739566|uniprotkb:Q53XV8|uniprotkb:Q9BUG4|uniprotkb:B3KQY1|uniprotkb:B3KRA2|uniprotkb:E0CX14|ensembl:ENSP00000254043|ensembl:ENSP00000377546	psi-mi:trx3_yeast(display_long)|uniprotkb:TRX3(gene name)|psi-mi:TRX3(display_short)|uniprotkb:YCR83W(orf name)|uniprotkb:YCR083W(locus name)	psi-mi:k1c15_human(display_long)|uniprotkb:KRT15(gene name)|psi-mi:KRT15(display_short)|uniprotkb:KRTB(gene name synonym)|uniprotkb:Cytokeratin-15(gene name synonym)|uniprotkb:Keratin-15(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549040|imex:IM-24995-2831	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR036249|refseq:NP_010006.1|sgd:S000000679|interpro:IPR017937|interpro:IPR013766(Thioredoxin domain)|rcsb pdb:2OE0|rcsb pdb:2OE1|rcsb pdb:2OE3|ensemblfungi:YCR083W(gene)|ensemblfungi:YCR083W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0015036"(disulfide oxidoreductase activity)|go:"GO:0034599"(cellular response to oxidative stress)|rcsb pdb:5YKW	refseq:NP_002266.2|ensembl:ENSG00000171346(gene)|ensembl:ENST00000254043(transcript)|ensembl:ENST00000393976(transcript)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0008544"(epidermis development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097110"(scaffold protein binding)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR039008|mint:P19012|reactome:R-HSA-6805567|reactome:R-HSA-6809371	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:g0xjGf9GvJRl8iv2qoT5tOs7jXI559292	rogid:WrZQBYQvrWcfrR5ojWXrXp6spPE9606	intact-crc:F3C3312879719F5B|rigid:rhj9ZjA14YeiQhCoKba8ZQBdWXI	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P01100	uniprotkb:P25372	intact:EBI-852851|uniprotkb:P18849|uniprotkb:A8K4E2|uniprotkb:B4DQ65|ensembl:ENSP00000306245	intact:EBI-19616|uniprotkb:D6VR84|ensemblfungi:YCR083W	psi-mi:fos_human(display_long)|uniprotkb:Cellular oncogene fos(gene name synonym)|uniprotkb:G0/G1 switch regulatory protein 7(gene name synonym)|uniprotkb:FOS(gene name)|psi-mi:FOS(display_short)|uniprotkb:G0S7(gene name synonym)	psi-mi:trx3_yeast(display_long)|uniprotkb:TRX3(gene name)|psi-mi:TRX3(display_short)|uniprotkb:YCR83W(orf name)|uniprotkb:YCR083W(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549028|imex:IM-24995-2828	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005243.1|dip:DIP-1047N|ensembl:ENSG00000170345(gene)|ensembl:ENST00000303562(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001661"(conditioned taste aversion)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006306"(DNA methylation)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006954"(inflammatory response)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007399"(nervous system development)|go:"GO:0007565"(female pregnancy)|go:"GO:0007568"(aging)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009409"(response to cold)|go:"GO:0009416"(response to light stimulus)|go:"GO:0009629"(response to gravity)|go:"GO:0009636"(response to toxic substance)|go:"GO:0016020"(membrane)|go:"GO:0030431"(sleep)|go:"GO:0031668"(cellular response to extracellular stimulus)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032570"(response to progesterone)|go:"GO:0032870"(cellular response to hormone stimulus)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034097"(response to cytokine)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035902"(response to immobilization stress)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0035976"(transcription factor AP-1 complex)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045672"(positive regulation of osteoclast differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051412"(response to corticosterone)|go:"GO:0051591"(response to cAMP)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000837(Fos transforming protein)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029816|rcsb pdb:1A02|rcsb pdb:1FOS|rcsb pdb:1S9K|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2871796|reactome:R-HSA-450341|reactome:R-HSA-6785807|reactome:R-HSA-6796648|reactome:R-HSA-9018519|reactome:R-HSA-9031628|reactome:R-HSA-9634638	interpro:IPR036249|refseq:NP_010006.1|sgd:S000000679|interpro:IPR017937|interpro:IPR013766(Thioredoxin domain)|rcsb pdb:2OE0|rcsb pdb:2OE1|rcsb pdb:2OE3|ensemblfungi:YCR083W(gene)|ensemblfungi:YCR083W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0015036"(disulfide oxidoreductase activity)|go:"GO:0034599"(cellular response to oxidative stress)|rcsb pdb:5YKW	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:R09jzTKeAyzIQYTQAsps2UWFyFE9606	rogid:g0xjGf9GvJRl8iv2qoT5tOs7jXI559292	intact-crc:AF4C40F3EC47E9B8|rigid:I9lOBxbMyqcagDUwjOiVWfRerZc	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P25372	uniprotkb:Q08379	intact:EBI-19616|uniprotkb:D6VR84|ensemblfungi:YCR083W	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	psi-mi:trx3_yeast(display_long)|uniprotkb:TRX3(gene name)|psi-mi:TRX3(display_short)|uniprotkb:YCR83W(orf name)|uniprotkb:YCR083W(locus name)	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549032|imex:IM-24995-2829	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR036249|refseq:NP_010006.1|sgd:S000000679|interpro:IPR017937|interpro:IPR013766(Thioredoxin domain)|rcsb pdb:2OE0|rcsb pdb:2OE1|rcsb pdb:2OE3|ensemblfungi:YCR083W(gene)|ensemblfungi:YCR083W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0015036"(disulfide oxidoreductase activity)|go:"GO:0034599"(cellular response to oxidative stress)|rcsb pdb:5YKW	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2017/05/26	rogid:g0xjGf9GvJRl8iv2qoT5tOs7jXI559292	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	intact-crc:C402DE9E01D0EDEA|rigid:nwv71IkwKmL4x3nV92ZKFMB1U+U	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P14373	uniprotkb:P25372	intact:EBI-719493|uniprotkb:A2BE15|uniprotkb:Q5RJA8|uniprotkb:Q5ST26|uniprotkb:Q6LA73|uniprotkb:Q6NXR9|uniprotkb:Q9BZY6|uniprotkb:Q9UJL3|ensembl:ENSP00000383555|ensembl:ENSP00000392787|ensembl:ENSP00000405229|ensembl:ENSP00000414793|ensembl:ENSP00000366404	intact:EBI-19616|uniprotkb:D6VR84|ensemblfungi:YCR083W	psi-mi:tri27_human(display_long)|uniprotkb:TRIM27(gene name)|psi-mi:TRIM27(display_short)|uniprotkb:RNF76(gene name synonym)|uniprotkb:RFP(gene name synonym)|uniprotkb:Ret finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 27(gene name synonym)|uniprotkb:RING finger protein 76(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM27(gene name synonym)	psi-mi:trx3_yeast(display_long)|uniprotkb:TRX3(gene name)|psi-mi:TRX3(display_short)|uniprotkb:YCR83W(orf name)|uniprotkb:YCR083W(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549036|imex:IM-24995-2830	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006501.1|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0090281"(negative regulation of calcium ion import)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR020457|interpro:IPR035791|interpro:IPR043136|mint:P14373|reactome:R-HSA-3232142|reactome:R-HSA-9635465|reactome:R-HSA-8948751|ensembl:ENSG00000204713(gene)|ensembl:ENSG00000215641(gene)|ensembl:ENSG00000229006(gene)|ensembl:ENSG00000234495(gene)|ensembl:ENSG00000237071(gene)|ensembl:ENST00000377199(transcript)|ensembl:ENST00000400720(transcript)|ensembl:ENST00000431123(transcript)|ensembl:ENST00000435528(transcript)|ensembl:ENST00000437160(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001650"(fibrillar center)|go:"GO:0002820"(negative regulation of adaptive immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)	interpro:IPR036249|refseq:NP_010006.1|sgd:S000000679|interpro:IPR017937|interpro:IPR013766(Thioredoxin domain)|rcsb pdb:2OE0|rcsb pdb:2OE1|rcsb pdb:2OE3|ensemblfungi:YCR083W(gene)|ensemblfungi:YCR083W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0015036"(disulfide oxidoreductase activity)|go:"GO:0034599"(cellular response to oxidative stress)|rcsb pdb:5YKW	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:dsfH5OUghD8KSaTz1SFw9OYVTK49606	rogid:g0xjGf9GvJRl8iv2qoT5tOs7jXI559292	intact-crc:80953ABBDF580EDF|rigid:or242VUGNkFq7Yqk1gx8Af1pjBQ	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q08379	uniprotkb:P26343	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	intact:EBI-5489|uniprotkb:D6VX97|ensemblfungi:YKR034W	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:dal80_yeast(display_long)|uniprotkb:YKR034W(locus name)|uniprotkb:DAL80(gene name)|psi-mi:DAL80(display_short)|uniprotkb:UGA43(gene name synonym)|uniprotkb:Regulatory protein UGA43(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549064|imex:IM-24995-2837	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N	refseq:NP_012959.1|sgd:S000001742|dip:DIP-2094N|ensemblfungi:YKR034W(gene)|ensemblfungi:YKR034W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042128"(nitrate assimilation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0090295"(nitrogen catabolite repression of transcription)|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR039355	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2017/05/26	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	rogid:Qfoc7DZ+/Nwthc4Hf93+iwuYgVg559292	intact-crc:0783AB16CFF998A5|rigid:/MJXVD3xlFybQYVPoql6KjIiCSY	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P24278	uniprotkb:P25638	intact:EBI-739899|uniprotkb:Q8IYH9|uniprotkb:B3KUX6|ensembl:ENSP00000378204|ensembl:ENSP00000476746	intact:EBI-21956|uniprotkb:D6VR65|ensemblfungi:YCR060W	psi-mi:zbt25_human(display_long)|uniprotkb:ZBTB25(gene name)|psi-mi:ZBTB25(display_short)|uniprotkb:KUP(gene name synonym)|uniprotkb:ZNF46(gene name synonym)|uniprotkb:Zinc finger protein 46(gene name synonym)|uniprotkb:Zinc finger protein KUP(gene name synonym)|uniprotkb:C14orf51(gene name synonym)	psi-mi:tah1_yeast(display_long)|uniprotkb:YCR60W(orf name)|uniprotkb:YCR060W(locus name)|uniprotkb:TAH1(gene name)|psi-mi:TAH1(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549060|imex:IM-24995-2836	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_008908.2|ensembl:ENSG00000089775(gene)|ensembl:ENST00000394715(transcript)|ensembl:ENST00000608382(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:P24278|refseq:NP_001291436.1|refseq:XP_011535445.1|refseq:XP_006720314.1|refseq:XP_006720315.1|refseq:XP_016877121.1|refseq:XP_016877122.1|refseq:XP_016877123.1|refseq:XP_016877124.1	refseq:NP_009986.1|sgd:S000000656|mint:P25638|dip:DIP-5000N|ensemblfungi:YCR060W(gene)|ensemblfungi:YCR060W_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|go:"GO:0051087"(chaperone binding)|go:"GO:0097255"(R2TP complex)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|rcsb pdb:2L6J|rcsb pdb:2LSU|rcsb pdb:2LSV|rcsb pdb:2MNJ|rcsb pdb:4CGQ|rcsb pdb:4CGU	-	-	crc64:3738DE6F227F803A	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:xi3bM5CoeXvVZNBOzaQlZdWU4ag9606	rogid:DXXWcBPtKzTtK2Hp7l4g0ukIZPQ559292	intact-crc:4ED7A45266538A6E|rigid:gnRe71VsITlsLNC5wTF4zzIJG8s	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O95751	uniprotkb:P25586	intact:EBI-740738|ensembl:ENSP00000359557|uniprotkb:Q6IAR6	intact:EBI-21773|uniprotkb:D6VQV7|ensemblfungi:YCL059C	psi-mi:ldoc1_human(display_long)|uniprotkb:Leucine zipper protein down-regulated in cancer cells(gene name synonym)|uniprotkb:LDOC1(gene name)|psi-mi:LDOC1(display_short)|uniprotkb:BCUR1(gene name synonym)	psi-mi:krr1_yeast(display_long)|uniprotkb:KRR1(gene name)|psi-mi:KRR1(display_short)|uniprotkb:KRR-R motif-containing protein 1(gene name synonym)|uniprotkb:Ribosomal RNA assembly protein KRR1(gene name synonym)|uniprotkb:YCL59C(orf name)|uniprotkb:YCL059C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549048|imex:IM-24995-2833	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_036449.1|ensembl:ENSG00000182195(gene)|ensembl:ENST00000370526(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071225"(cellular response to muramyl dipeptide)|interpro:IPR032549|interpro:IPR032567	refseq:NP_009872.1|sgd:S000000564|mint:P25586|dip:DIP-1408N|ensemblfungi:YCL059C_mRNA(transcript)|go:"GO:0000447"("endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0030686"(90S preribosome)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0032040"(small-subunit processome)|go:"GO:0042274"(ribosomal small subunit biogenesis)|interpro:IPR004087(K Homology)|interpro:IPR024166|interpro:IPR036612|interpro:IPR041174|rcsb pdb:4QMF|rcsb pdb:5WLC|rcsb pdb:5WYJ|rcsb pdb:5WYK|rcsb pdb:6KE6|rcsb pdb:6LQP|rcsb pdb:6LQQ|rcsb pdb:6LQU|rcsb pdb:6ZQA|rcsb pdb:6ZQB|rcsb pdb:6ZQC|rcsb pdb:7AJT|reactome:R-SCE-6791226|ensemblfungi:YCL059C(gene)	-	-	crc64:7A7F964E2C7FD056	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Ediu0oNiZ/+YVY8l3fNdgP5A+v09606	rogid:wveCX/DmVjCNLOIejb/nWbrbX3o559292	intact-crc:207B1C2DFF607951|rigid:Fb8dyjYSS1xcF+wKlzG0bFqw6nQ	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O14874	uniprotkb:P25631	intact:EBI-1046765|uniprotkb:Q96IN5|uniprotkb:Q6FGL4|intact:EBI-1210327|uniprotkb:A8MY43|uniprotkb:Q96G95|ensembl:ENSP00000219794|ensembl:ENSP00000378405	intact:EBI-2347265|uniprotkb:D6VR59|ensemblfungi:YCR051W	psi-mi:bckd_human(display_long)|uniprotkb:Branched-chain alpha-ketoacid dehydrogenase kinase(gene name synonym)|uniprotkb:BCKDK(gene name)|psi-mi:BCKDK(display_short)	psi-mi:ycu1_yeast(display_long)|uniprotkb:YCR51W(orf name)|uniprotkb:YCR051W(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549052|imex:IM-24995-2834	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005872.2|go:"GO:0005947"(mitochondrial alpha-ketoglutarate dehydrogenase complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006550"(isoleucine catabolic process)|go:"GO:0006552"(leucine catabolic process)|go:"GO:0006574"(valine catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009063"(cellular amino acid catabolic process)|go:"GO:0009083"(branched-chain amino acid catabolic process)|go:"GO:0010906"(regulation of glucose metabolic process)|go:"GO:0016301"(kinase activity)|go:"GO:0016310"(phosphorylation)|go:"GO:0045763"(negative regulation of cellular amino acid metabolic process)|go:"GO:0047323"("[3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring)] kinase activity")|interpro:IPR003594(ATP-binding region, ATPase-like)|refseq:NP_001116429.1|refseq:NP_001258855.1|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR018955|go:"GO:0005759"(mitochondrial matrix)|interpro:IPR036784|interpro:IPR036890|interpro:IPR039028|mint:O14874|reactome:R-HSA-70895|ensembl:ENSG00000103507(gene)|ensembl:ENST00000219794(transcript)|ensembl:ENST00000394951(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004740"("pyruvate dehydrogenase (acetyl-transferring) kinase activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)	refseq:NP_009980.1|sgd:S000000647|interpro:IPR002110(Ankyrin)|interpro:IPR036770|ensemblfungi:YCR051W(gene)|ensemblfungi:YCR051W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:0hiSb7/qtSPoHt/cmLnUo7Gq6OI9606	rogid:xSvXYNOUhBZjJgwGzwJ+muPq8tU559292	intact-crc:505CD68FF6561570|rigid:yZ1XK5JunV7csCewqliY0rXO2FY	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P25635	uniprotkb:O00635	intact:EBI-14332|uniprotkb:P25633|uniprotkb:P25636|uniprotkb:D6VR63|ensemblfungi:YCR057C	intact:EBI-2130415|uniprotkb:B2R862|ensembl:ENSP00000349596	psi-mi:pwp2_yeast(display_long)|uniprotkb:PWP2(gene name)|psi-mi:PWP2(display_short)|uniprotkb:UTP1(gene name synonym)|uniprotkb:YCR057C(locus name)|uniprotkb:YCR55C/YCR57C/YCR58C(orf name)|uniprotkb:U3 small nucleolar RNA-associated protein 1(gene name synonym)|uniprotkb:U three protein 1(gene name synonym)	psi-mi:tri38_human(display_long)|uniprotkb:TRIM38(gene name)|psi-mi:TRIM38(display_short)|uniprotkb:RNF15(gene name synonym)|uniprotkb:RORET(gene name synonym)|uniprotkb:RING finger protein 15(gene name synonym)|uniprotkb:Zinc finger protein RoRet(gene name synonym)|uniprotkb:Tripartite motif-containing protein 38(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM38(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549056|imex:IM-24995-2835	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0000920"(septum digestion after cytokinesis)|go:"GO:0003729"(mRNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030686"(90S preribosome)|go:"GO:0032040"(small-subunit processome)|go:"GO:0034388"(Pwp2p-containing subcomplex of 90S preribosome)|interpro:IPR001680(WD40 repeat)|interpro:IPR007148(Small-subunit processome, Utp12)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR027145|interpro:IPR036322|rcsb pdb:5I2T|rcsb pdb:5WLC|rcsb pdb:5WYJ|ensemblfungi:YCR057C(gene)|ensemblfungi:YCR057C_mRNA(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0000447"("endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|rcsb pdb:5WYK|go:"GO:0000472"("endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000480"("endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|rcsb pdb:6KE6|rcsb pdb:6LQP|rcsb pdb:6LQQ|rcsb pdb:6LQR|rcsb pdb:6LQS|rcsb pdb:6LQT|rcsb pdb:6LQU|rcsb pdb:6LQV|rcsb pdb:6ND4|rcsb pdb:6ZQA|rcsb pdb:6ZQB|rcsb pdb:6ZQC|rcsb pdb:6ZQD|rcsb pdb:6ZQE|rcsb pdb:6ZQF|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-6791226|refseq:NP_009984.1|sgd:S000000653|mint:P25635|dip:DIP-1868N	refseq:NP_006346.1|refseq:XP_005248856.1|refseq:XP_005248857.1|ensembl:ENSG00000112343(gene)|ensembl:ENST00000357085(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046598"(positive regulation of viral entry into host cell)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR035790|interpro:IPR043136|reactome:R-HSA-877300	-	crc64:CBEE4720F81378B6	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:3JKhaE50yPlCymnkEC14JB9atNY559292	rogid:Zh4X/6v/qKZlDkMV6hhn7OsvPnQ9606	intact-crc:465C50CD0160A811|rigid:5UniEi26OZCrhkjs49PI/+pPHEk	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O15156-2	uniprotkb:P28004	intact:EBI-11522250|ensembl:ENSP00000406286	intact:EBI-20640|uniprotkb:D6VPI6|ensemblfungi:YAL032C	psi-mi:o15156-2(display_long)|uniprotkb:ZBTB7B(gene name)|psi-mi:ZBTB7B(display_short)|uniprotkb:Krueppel-related zinc finger protein cKrox(gene name synonym)|uniprotkb:T-helper-inducing POZ/Krueppel-like factor(gene name synonym)|uniprotkb:ZBTB15(gene name synonym)|uniprotkb:ZFP67(gene name synonym)|uniprotkb:ZNF857B(gene name synonym)|uniprotkb:Zinc finger and BTB domain-containing protein 15(gene name synonym)|uniprotkb:Zinc finger protein 67 homolog(gene name synonym)|uniprotkb:Zinc finger protein 857B(gene name synonym)|uniprotkb:Zinc finger protein Th-POK(gene name synonym)	psi-mi:prp45_yeast(display_long)|uniprotkb:YAL032C(locus name)|uniprotkb:PRP45(gene name)|psi-mi:PRP45(display_short)|uniprotkb:FUN20(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549080|imex:IM-24995-2841	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-740434(isoform-parent)|ensembl:ENSG00000160685(gene)|ensembl:ENST00000417934(transcript)|uniprotkb:O15156-2(isoform-parent)	refseq:NP_009370.1|sgd:S000000030|ensemblfungi:YAL032C(gene)|ensemblfungi:YAL032C_mRNA(transcript)|go:"GO:0000350"(generation of catalytic spliceosome for second transesterification step)|go:"GO:0005634"(nucleus)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|interpro:IPR004015(SKIP/SNW)|interpro:IPR017862|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|dip:DIP-2774N|mint:P28004	-	isoform-comment:No experimental confirmation available.	crc64:FE5A724186D7FE84	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:41NEFYyprTXI+fOHVFh78TPKF289606	rogid:qoHF1UsO3k+JOTOfigSuy2P84/k559292	intact-crc:837521C2C2B9B71E|rigid:8oaC+Ggh9JirICSVORCrzjxdpwY	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P26448	uniprotkb:O15156-2	intact:EBI-3824|uniprotkb:D6VZN0|ensemblfungi:YMR055C	intact:EBI-11522250|ensembl:ENSP00000406286	psi-mi:bub2_yeast(display_long)|uniprotkb:BUB2(gene name)|psi-mi:BUB2(display_short)|uniprotkb:YMR055C(locus name)|uniprotkb:YM9796.08C(orf name)|uniprotkb:Cell cycle arrest protein BUB2(gene name synonym)	psi-mi:o15156-2(display_long)|uniprotkb:ZBTB7B(gene name)|psi-mi:ZBTB7B(display_short)|uniprotkb:Krueppel-related zinc finger protein cKrox(gene name synonym)|uniprotkb:T-helper-inducing POZ/Krueppel-like factor(gene name synonym)|uniprotkb:ZBTB15(gene name synonym)|uniprotkb:ZFP67(gene name synonym)|uniprotkb:ZNF857B(gene name synonym)|uniprotkb:Zinc finger and BTB domain-containing protein 15(gene name synonym)|uniprotkb:Zinc finger protein 67 homolog(gene name synonym)|uniprotkb:Zinc finger protein 857B(gene name synonym)|uniprotkb:Zinc finger protein Th-POK(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549068|imex:IM-24995-2838	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013771.1|sgd:S000004659|dip:DIP-1215N|mint:P26448|ensemblfungi:YMR055C(gene)|ensemblfungi:YMR055C_mRNA(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0031030"(negative regulation of septation initiation signaling)|go:"GO:0031578"(mitotic spindle orientation checkpoint signaling)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0051301"(cell division)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:1902543"(negative regulation of protein localization to mitotic spindle pole body)|go:"GO:1990334"(Bfa1-Bub2 complex)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR035969	intact:EBI-740434(isoform-parent)|ensembl:ENSG00000160685(gene)|ensembl:ENST00000417934(transcript)|uniprotkb:O15156-2(isoform-parent)	-	crc64:A1DDBFB548E81EA3	isoform-comment:No experimental confirmation available.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:+03m4HOOcKjpSjqpEZ8wCgD2Egc559292	rogid:41NEFYyprTXI+fOHVFh78TPKF289606	intact-crc:280C650314C3A318|rigid:ahVGA7Cxy0MID1b7oFyljnjiRUM	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P10644	uniprotkb:P27344	intact:EBI-476431|uniprotkb:Q567S7|uniprotkb:K7ER48|ensembl:ENSP00000351410|ensembl:ENSP00000376475|ensembl:ENSP00000445625|ensembl:ENSP00000464977|ensembl:ENSP00000466459	intact:EBI-6076|uniprotkb:D6VQS3|ensemblfungi:YBR278W	psi-mi:kap0_human(display_long)|uniprotkb:Tissue-specific extinguisher 1(gene name synonym)|uniprotkb:PRKAR1A(gene name)|psi-mi:PRKAR1A(display_short)|uniprotkb:PKR1(gene name synonym)|uniprotkb:PRKAR1(gene name synonym)|uniprotkb:TSE1(gene name synonym)	psi-mi:dpb3_yeast(display_long)|uniprotkb:DPB3(gene name)|psi-mi:DPB3(display_short)|uniprotkb:YBR278W(locus name)|uniprotkb:YBR2015(orf name)|uniprotkb:DNA polymerase II subunit C(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549072|imex:IM-24995-2839	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002725.1|refseq:NP_997636.1|refseq:NP_997637.1|refseq:XP_011523285.1|refseq:XP_011523286.1|refseq:XP_011523287.1|refseq:NP_001263218.1|refseq:NP_001263219.1|refseq:NP_001265362.1|dip:DIP-34368N|ensembl:ENSG00000108946(gene)|ensembl:ENST00000358598(transcript)|ensembl:ENST00000392711(transcript)|ensembl:ENST00000536854(transcript)|ensembl:ENST00000586397(transcript)|ensembl:ENST00000589228(transcript)|go:"GO:0001707"(mesoderm formation)|go:"GO:0004862"(cAMP-dependent protein kinase inhibitor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005771"(multivesicular body)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005952"(cAMP-dependent protein kinase complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007143"(female meiotic nuclear division)|go:"GO:0008603"(cAMP-dependent protein kinase regulator activity)|go:"GO:0010738"(regulation of protein kinase A signaling)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030552"(cAMP binding)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043949"(regulation of cAMP-mediated signaling)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045835"(negative regulation of meiotic nuclear division)|go:"GO:0046007"(negative regulation of activated T cell proliferation)|go:"GO:0060038"(cardiac muscle cell proliferation)|go:"GO:0097224"(sperm connecting piece)|go:"GO:0097546"(ciliary base)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:2000480"(negative regulation of cAMP-dependent protein kinase activity)|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR003117(cAMP-dependent protein kinase, regulatory subunit, type I/II alpha/beta)|interpro:IPR012198(cAMP-dependent protein kinase regulatory subunit)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR018488|rcsb pdb:5KJZ|reactome:R-HSA-163615|reactome:R-HSA-164378|reactome:R-HSA-180024|reactome:R-HSA-381676|reactome:R-HSA-432040|reactome:R-HSA-442720|reactome:R-HSA-5610787|reactome:R-HSA-9660821|reactome:R-HSA-9664323|reactome:R-HSA-983231|interpro:IPR018490|mint:P10644|rcsb pdb:5KJX|rcsb pdb:5KJY	refseq:NP_009837.1|sgd:S000000482|dip:DIP-4803N|mint:P27344|ensemblfungi:YBR278W(gene)|ensemblfungi:YBR278W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006272"(leading strand elongation)|go:"GO:0008622"(epsilon DNA polymerase complex)|go:"GO:0008623"(CHRAC)|go:"GO:0042276"(error-prone translesion synthesis)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0070868"(obsolete heterochromatin organization involved in chromatin silencing)|go:"GO:0090305"(nucleic acid phosphodiester bond hydrolysis)|interpro:IPR009072(Histone-fold)|rcsb pdb:6WJV|reactome:R-SCE-5656169|reactome:R-SCE-6782135|reactome:R-SCE-68952|reactome:R-SCE-68962	-	-	crc64:288913917D49C7F9	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:dUZaCJQnC0KZEG4pccIqoT066VY9606	rogid:vWWMmgZ4w7G1VF2V2TDY8cZpKas559292	intact-crc:F6F7E8200CC79C9B|rigid:DsFGaxwbG19Q0h9U1iDVuL5sUZw	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P19012	uniprotkb:P28004	intact:EBI-739566|uniprotkb:Q53XV8|uniprotkb:Q9BUG4|uniprotkb:B3KQY1|uniprotkb:B3KRA2|uniprotkb:E0CX14|ensembl:ENSP00000254043|ensembl:ENSP00000377546	intact:EBI-20640|uniprotkb:D6VPI6|ensemblfungi:YAL032C	psi-mi:k1c15_human(display_long)|uniprotkb:KRT15(gene name)|psi-mi:KRT15(display_short)|uniprotkb:KRTB(gene name synonym)|uniprotkb:Cytokeratin-15(gene name synonym)|uniprotkb:Keratin-15(gene name synonym)	psi-mi:prp45_yeast(display_long)|uniprotkb:YAL032C(locus name)|uniprotkb:PRP45(gene name)|psi-mi:PRP45(display_short)|uniprotkb:FUN20(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549076|imex:IM-24995-2840	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002266.2|ensembl:ENSG00000171346(gene)|ensembl:ENST00000254043(transcript)|ensembl:ENST00000393976(transcript)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0008544"(epidermis development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097110"(scaffold protein binding)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR039008|mint:P19012|reactome:R-HSA-6805567|reactome:R-HSA-6809371	refseq:NP_009370.1|sgd:S000000030|ensemblfungi:YAL032C(gene)|ensemblfungi:YAL032C_mRNA(transcript)|go:"GO:0000350"(generation of catalytic spliceosome for second transesterification step)|go:"GO:0005634"(nucleus)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|interpro:IPR004015(SKIP/SNW)|interpro:IPR017862|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|dip:DIP-2774N|mint:P28004	-	-	crc64:FE5A724186D7FE84	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:WrZQBYQvrWcfrR5ojWXrXp6spPE9606	rogid:qoHF1UsO3k+JOTOfigSuy2P84/k559292	intact-crc:292FDF697A1563EA|rigid:4w+BxVSaSSy0ukWUMAf8EPr4mzM	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:A0A087X1U9	uniprotkb:P29703	intact:EBI-11525184|ensembl:ENSP00000484475	intact:EBI-14814|uniprotkb:D6VXR6|ensemblfungi:YKL019W	psi-mi:a0a087x1u9_human(display_long)|uniprotkb:GAK(gene name)|psi-mi:GAK(display_short)	psi-mi:fnta_yeast(display_long)|uniprotkb:YKL019W(locus name)|uniprotkb:RAM2(gene name)|psi-mi:RAM2(display_short)|uniprotkb:CAAX farnesyltransferase subunit alpha(gene name synonym)|uniprotkb:Ras proteins prenyltransferase subunit alpha(gene name synonym)|uniprotkb:FTase-alpha(gene name synonym)|uniprotkb:Type I protein geranyl-geranyltransferase subunit alpha(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549100|imex:IM-24995-2846	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000178950(gene)|ensembl:ENST00000618573(transcript)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR036869	sgd:S000001502|refseq:NP_012906.3|go:"GO:0004662"(CAAX-protein geranylgeranyltransferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005953"(CAAX-protein geranylgeranyltransferase complex)|go:"GO:0005965"(protein farnesyltransferase complex)|go:"GO:0007323"(peptide pheromone maturation)|go:"GO:0018343"(protein farnesylation)|go:"GO:0018344"(protein geranylgeranylation)|interpro:IPR002088(Protein prenyltransferase, alpha subunit)|reactome:R-SCE-9648002|ensemblfungi:YKL019W(gene)|ensemblfungi:YKL019W_mRNA(transcript)|go:"GO:0004660"(protein farnesyltransferase activity)|go:"GO:0004661"(protein geranylgeranyltransferase activity)|dip:DIP-1233N|mint:P29703	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:9cLiPH0B6Uj9kREXyEJ+0f2ZQWw9606	rogid:u2rtpSuSW9Zd8LHWmniip7r5Ycs559292	intact-crc:A3D69E61CDD7E9A1|rigid:3E6Ybvs/yLKLs7QpduyvkOxXCSA	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P28272	uniprotkb:P14136	intact:EBI-14386|uniprotkb:Q2XN75|uniprotkb:Q70DC7|uniprotkb:D6VWY7|ensemblfungi:YKL216W	intact:EBI-744302|uniprotkb:Q53H98|uniprotkb:Q5D055|uniprotkb:Q6ZQS3|uniprotkb:Q7Z5J6|uniprotkb:Q7Z5J7|uniprotkb:Q96KS4|uniprotkb:Q96P18|uniprotkb:Q9UFD0|uniprotkb:B2RD44|uniprotkb:D3DX59|intact:EBI-3909365|uniprotkb:E9PAX3|ensembl:ENSP00000466598|uniprotkb:A7REI1	psi-mi:pyrd_yeast(display_long)|uniprotkb:YKL216W(locus name)|uniprotkb:URA1(gene name)|psi-mi:URA1(display_short)|uniprotkb:Dihydroorotate oxidase(gene name synonym)	psi-mi:gfap_human(display_long)|uniprotkb:GFAP(gene name)|psi-mi:GFAP(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549096|imex:IM-24995-2845	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR023359|interpro:IPR024920|interpro:IPR033886|ensemblfungi:YKL216W(gene)|ensemblfungi:YKL216W_mRNA(transcript)|go:"GO:0004152"(dihydroorotate dehydrogenase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006207"('de novo' pyrimidine nucleobase biosynthetic process)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0044205"('de novo' UMP biosynthetic process)|go:"GO:1990663"("dihydroorotate dehydrogenase (fumarate) activity")|interpro:IPR001295(Dihydroorotate dehydrogenase, core)|interpro:IPR005720(Dihydroorotate dehydrogenase, class 1, core)|interpro:IPR012135(Dihydroorotate dehydrogenase, classes 1 and 2)|interpro:IPR013785(Aldolase-type TIM barrel)|refseq:NP_012706.1|sgd:S000001699|mint:P28272|dip:DIP-6573N	refseq:NP_001124491.1|refseq:NP_001229305.1|refseq:NP_002046.1|ensembl:ENSG00000131095(gene)|ensembl:ENST00000588735(transcript)|go:"GO:0005178"(integrin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0009611"(response to wounding)|go:"GO:0010467"(gene expression)|go:"GO:0010625"(positive regulation of Schwann cell proliferation)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0014002"(astrocyte development)|go:"GO:0019900"(kinase binding)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0031102"(neuron projection regeneration)|go:"GO:0042802"(identical protein binding)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0044297"(cell body)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0051580"(regulation of neurotransmitter uptake)|go:"GO:0060020"(Bergmann glial cell differentiation)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0070779"(D-aspartate import across plasma membrane)|go:"GO:0097450"(astrocyte end-foot)|go:"GO:0098574"(cytoplasmic side of lysosomal membrane)|go:"GO:1904714"(regulation of chaperone-mediated autophagy)|interpro:IPR006821(Intermediate filament, DNA-binding region)|interpro:IPR018039|interpro:IPR027701|interpro:IPR039008|mint:P14136|rcsb pdb:6A9P|reactome:R-HSA-1251985|reactome:R-HSA-9613829	-	crc64:0F1FF9BDA7F8D68E	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:EXmeAujwfMfvIaNkgvsl3YgWvPs559292	rogid:Pz4JW0WjMjBYILTDSX9jUmMqWhg9606	intact-crc:FEDCEAFFBAADE204|rigid:AAroZq4KgO2UidBnxyZ6aHWVpTA	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P28004	uniprotkb:O95751	intact:EBI-20640|uniprotkb:D6VPI6|ensemblfungi:YAL032C	intact:EBI-740738|ensembl:ENSP00000359557|uniprotkb:Q6IAR6	psi-mi:prp45_yeast(display_long)|uniprotkb:YAL032C(locus name)|uniprotkb:PRP45(gene name)|psi-mi:PRP45(display_short)|uniprotkb:FUN20(gene name synonym)	psi-mi:ldoc1_human(display_long)|uniprotkb:Leucine zipper protein down-regulated in cancer cells(gene name synonym)|uniprotkb:LDOC1(gene name)|psi-mi:LDOC1(display_short)|uniprotkb:BCUR1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549084|imex:IM-24995-2842	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009370.1|sgd:S000000030|ensemblfungi:YAL032C(gene)|ensemblfungi:YAL032C_mRNA(transcript)|go:"GO:0000350"(generation of catalytic spliceosome for second transesterification step)|go:"GO:0005634"(nucleus)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|interpro:IPR004015(SKIP/SNW)|interpro:IPR017862|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|dip:DIP-2774N|mint:P28004	refseq:NP_036449.1|ensembl:ENSG00000182195(gene)|ensembl:ENST00000370526(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071225"(cellular response to muramyl dipeptide)|interpro:IPR032549|interpro:IPR032567	-	crc64:FE5A724186D7FE84	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:qoHF1UsO3k+JOTOfigSuy2P84/k559292	rogid:Ediu0oNiZ/+YVY8l3fNdgP5A+v09606	intact-crc:741ADA3D4E3E7E14|rigid:5eAIzeJUFQEBthjaT++xS7X6z0Y	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q08379	uniprotkb:P28004	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	intact:EBI-20640|uniprotkb:D6VPI6|ensemblfungi:YAL032C	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:prp45_yeast(display_long)|uniprotkb:YAL032C(locus name)|uniprotkb:PRP45(gene name)|psi-mi:PRP45(display_short)|uniprotkb:FUN20(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549088|imex:IM-24995-2843	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N	refseq:NP_009370.1|sgd:S000000030|ensemblfungi:YAL032C(gene)|ensemblfungi:YAL032C_mRNA(transcript)|go:"GO:0000350"(generation of catalytic spliceosome for second transesterification step)|go:"GO:0005634"(nucleus)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|interpro:IPR004015(SKIP/SNW)|interpro:IPR017862|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|dip:DIP-2774N|mint:P28004	-	-	crc64:FE5A724186D7FE84	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2017/05/26	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	rogid:qoHF1UsO3k+JOTOfigSuy2P84/k559292	intact-crc:164863EA8919C2DB|rigid:X6brJ2YxTeJSL1sKbSylOWcmUo0	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P28004	uniprotkb:P14373	intact:EBI-20640|uniprotkb:D6VPI6|ensemblfungi:YAL032C	intact:EBI-719493|uniprotkb:A2BE15|uniprotkb:Q5RJA8|uniprotkb:Q5ST26|uniprotkb:Q6LA73|uniprotkb:Q6NXR9|uniprotkb:Q9BZY6|uniprotkb:Q9UJL3|ensembl:ENSP00000383555|ensembl:ENSP00000392787|ensembl:ENSP00000405229|ensembl:ENSP00000414793|ensembl:ENSP00000366404	psi-mi:prp45_yeast(display_long)|uniprotkb:YAL032C(locus name)|uniprotkb:PRP45(gene name)|psi-mi:PRP45(display_short)|uniprotkb:FUN20(gene name synonym)	psi-mi:tri27_human(display_long)|uniprotkb:TRIM27(gene name)|psi-mi:TRIM27(display_short)|uniprotkb:RNF76(gene name synonym)|uniprotkb:RFP(gene name synonym)|uniprotkb:Ret finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 27(gene name synonym)|uniprotkb:RING finger protein 76(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM27(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549092|imex:IM-24995-2844	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009370.1|sgd:S000000030|ensemblfungi:YAL032C(gene)|ensemblfungi:YAL032C_mRNA(transcript)|go:"GO:0000350"(generation of catalytic spliceosome for second transesterification step)|go:"GO:0005634"(nucleus)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|interpro:IPR004015(SKIP/SNW)|interpro:IPR017862|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|dip:DIP-2774N|mint:P28004	refseq:NP_006501.1|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0090281"(negative regulation of calcium ion import)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR020457|interpro:IPR035791|interpro:IPR043136|mint:P14373|reactome:R-HSA-3232142|reactome:R-HSA-9635465|reactome:R-HSA-8948751|ensembl:ENSG00000204713(gene)|ensembl:ENSG00000215641(gene)|ensembl:ENSG00000229006(gene)|ensembl:ENSG00000234495(gene)|ensembl:ENSG00000237071(gene)|ensembl:ENST00000377199(transcript)|ensembl:ENST00000400720(transcript)|ensembl:ENST00000431123(transcript)|ensembl:ENST00000435528(transcript)|ensembl:ENST00000437160(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001650"(fibrillar center)|go:"GO:0002820"(negative regulation of adaptive immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)	-	crc64:FE5A724186D7FE84	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:qoHF1UsO3k+JOTOfigSuy2P84/k559292	rogid:dsfH5OUghD8KSaTz1SFw9OYVTK49606	intact-crc:EDE42BB8558E7650|rigid:l1EOZvLuHrmcXFflP1U/fSP6oOQ	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P31153	uniprotkb:P19358	intact:EBI-1050743|uniprotkb:Q53SP5|uniprotkb:A8K511|uniprotkb:D6W5L1|ensembl:ENSP00000303147|uniprotkb:B4DN45	intact:EBI-10795|uniprotkb:E9P927|ensemblfungi:YDR502C|uniprotkb:D6VTC4	psi-mi:metk2_human(display_long)|uniprotkb:Methionine adenosyltransferase 2(gene name synonym)|uniprotkb:Methionine adenosyltransferase II(gene name synonym)|uniprotkb:MAT2A(gene name)|psi-mi:MAT2A(display_short)|uniprotkb:AMS2(gene name synonym)|uniprotkb:MATA2(gene name synonym)	psi-mi:metk2_yeast(display_long)|uniprotkb:SAM2(gene name)|psi-mi:SAM2(display_short)|uniprotkb:ETH2(gene name synonym)|uniprotkb:YDR502C(locus name)|uniprotkb:D9719.8(orf name)|uniprotkb:Methionine adenosyltransferase 2(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549116|imex:IM-24995-2850	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005902.1|rcsb pdb:5A1G|rcsb pdb:5A1I|rcsb pdb:5UGH|rcsb pdb:6FAJ|rcsb pdb:6FBN|rcsb pdb:6FBO|rcsb pdb:6FBP|rcsb pdb:6FCB|rcsb pdb:6FCD|rcsb pdb:6FWB|ensembl:ENSG00000168906(gene)|ensembl:ENST00000306434(transcript)|go:"GO:0004478"(methionine adenosyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006556"(S-adenosylmethionine biosynthetic process)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0034214"(protein hexamerization)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048269"(methionine adenosyltransferase complex)|go:"GO:0051291"(protein heterooligomerization)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR002133(S-adenosylmethionine synthetase)|rcsb pdb:6G6R|rcsb pdb:6P9V|rcsb pdb:6WKB|interpro:IPR022628|rcsb pdb:7BHR|rcsb pdb:7BHS|interpro:IPR022629|interpro:IPR022630|interpro:IPR022631|interpro:IPR022636|mint:P31153|rcsb pdb:2P02|rcsb pdb:4KTT|rcsb pdb:4KTV|rcsb pdb:4NDN|rcsb pdb:5A19|rcsb pdb:7BHT|rcsb pdb:7BHU|rcsb pdb:7BHV|rcsb pdb:7BHW|rcsb pdb:7BHX|rcsb pdb:7KCC|rcsb pdb:7KCE|rcsb pdb:7KCF|rcsb pdb:7KDA|rcsb pdb:7KDB|rcsb pdb:7L1A|reactome:R-HSA-156581	ensemblfungi:YDR502C(gene)|ensemblfungi:YDR502C_mRNA(transcript)|go:"GO:0006556"(S-adenosylmethionine biosynthetic process)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0046872"(metal ion binding)|interpro:IPR002133(S-adenosylmethionine synthetase)|interpro:IPR022628|interpro:IPR022629|interpro:IPR022630|interpro:IPR022631|interpro:IPR022636|reactome:R-SCE-156581|reactome:R-SCE-1614635|reactome:R-SCE-2408508|go:"GO:0004478"(methionine adenosyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006555"(methionine metabolic process)|sgd:S000002910|refseq:NP_010790.3|mint:P19358|dip:DIP-4001N	-	-	crc64:0AFCB0BA386F088B	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:8QDKkbuHcvQtfzy2XkVjCKjTK709606	rogid:fLg9TMOk+nR4ZuRNqkqur0qzv/E559292	intact-crc:1875D22758CBBF55|rigid:OAdSwEtKPQ2xBwonkNrjPt/ZKpY	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P29703	uniprotkb:Q8N5R6	intact:EBI-14814|uniprotkb:D6VXR6|ensemblfungi:YKL019W	intact:EBI-740841|intact:EBI-953781|uniprotkb:B3KQ49|uniprotkb:A8K3U4|uniprotkb:A8MPQ6|uniprotkb:A8MV61|uniprotkb:A8MVU9|uniprotkb:Q9H5Q6|uniprotkb:Q8TAX6|intact:EBI-2320546|intact:EBI-11522976	psi-mi:fnta_yeast(display_long)|uniprotkb:YKL019W(locus name)|uniprotkb:RAM2(gene name)|psi-mi:RAM2(display_short)|uniprotkb:CAAX farnesyltransferase subunit alpha(gene name synonym)|uniprotkb:Ras proteins prenyltransferase subunit alpha(gene name synonym)|uniprotkb:FTase-alpha(gene name synonym)|uniprotkb:Type I protein geranyl-geranyltransferase subunit alpha(gene name synonym)	psi-mi:ccd33_human(display_long)|uniprotkb:CCDC33(gene name)|psi-mi:CCDC33(display_short)|uniprotkb:Cancer/testis antigen 61(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549104|imex:IM-24995-2847	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000001502|refseq:NP_012906.3|go:"GO:0004662"(CAAX-protein geranylgeranyltransferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005953"(CAAX-protein geranylgeranyltransferase complex)|go:"GO:0005965"(protein farnesyltransferase complex)|go:"GO:0007323"(peptide pheromone maturation)|go:"GO:0018343"(protein farnesylation)|go:"GO:0018344"(protein geranylgeranylation)|interpro:IPR002088(Protein prenyltransferase, alpha subunit)|reactome:R-SCE-9648002|ensemblfungi:YKL019W(gene)|ensemblfungi:YKL019W_mRNA(transcript)|go:"GO:0004660"(protein farnesyltransferase activity)|go:"GO:0004661"(protein geranylgeranyltransferase activity)|dip:DIP-1233N|mint:P29703	refseq:NP_079331.3|interpro:IPR000008(C2 calcium-dependent membrane targeting)|go:"GO:0005777"(peroxisome)|refseq:NP_001274110.1|refseq:NP_877592.2|mint:Q8N5R6|interpro:IPR035892|interpro:IPR039889	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2021/11/30	rogid:u2rtpSuSW9Zd8LHWmniip7r5Ycs559292	rogid:eEIn7pQyfdHWx8TeLJpYy0i/gww9606	intact-crc:640AA05EA806060E|rigid:eNKRXOiTEKxKnSyeUuxyrUsxuiE	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P30260-2	uniprotkb:P15873	intact:EBI-11523497|ensembl:ENSP00000434614	intact:EBI-12993|uniprotkb:D6VQ89|ensemblfungi:YBR088C	psi-mi:p30260-2(display_long)|uniprotkb:CDC27(gene name)|psi-mi:CDC27(display_short)|uniprotkb:ANAPC3(gene name synonym)|uniprotkb:Anaphase-promoting complex subunit 3(gene name synonym)|uniprotkb:CDC27 homolog(gene name synonym)|uniprotkb:D0S1430E(gene name synonym)|uniprotkb:D17S978E(gene name synonym)|uniprotkb:H-NUC(gene name synonym)	psi-mi:pcna_yeast(display_long)|uniprotkb:YBR0811(orf name)|uniprotkb:YBR088C(locus name)|uniprotkb:POL30(gene name)|psi-mi:POL30(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549108|imex:IM-24995-2848	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000004897(gene)|ensembl:ENST00000531206(transcript)|intact:EBI-994813(isoform-parent)	refseq:NP_009645.1|sgd:S000000292|go:"GO:0043626"(PCNA complex)|go:"GO:0070987"(error-free translesion synthesis)|go:"GO:1902394"(positive regulation of exodeoxyribonuclease activity)|go:"GO:1903022"(positive regulation of phosphodiesterase activity, acting on 3'-phosphoglycolate-terminated DNA strands)|go:"GO:1905779"(positive regulation of exonuclease activity)|interpro:IPR000730(Proliferating cell nuclear antigen, PCNA)|interpro:IPR022648|interpro:IPR022649|interpro:IPR022659|rcsb pdb:1PLQ|rcsb pdb:1PLR|rcsb pdb:1SXJ|rcsb pdb:2OD8|rcsb pdb:3F1W|rcsb pdb:3GPM|rcsb pdb:3GPN|rcsb pdb:3L0W|rcsb pdb:4L6P|rcsb pdb:3L0X|rcsb pdb:3L10|rcsb pdb:4YHR|rcsb pdb:3PGE|rcsb pdb:3V60|rcsb pdb:3V61|rcsb pdb:3V62|rcsb pdb:5JNE|rcsb pdb:4L60|mint:P15873|dip:DIP-2417N|go:"GO:0035753"(maintenance of DNA trinucleotide repeats)|ensemblfungi:YBR088C(gene)|ensemblfungi:YBR088C_mRNA(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000710"(meiotic mismatch repair)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005657"(replication fork)|go:"GO:0006272"(leading strand elongation)|go:"GO:0006273"(lagging strand elongation)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006298"(mismatch repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0006348"|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0019985"(translesion synthesis)|go:"GO:0030337"(DNA polymerase processivity factor activity)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0034087"(establishment of mitotic sister chromatid cohesion)|go:"GO:0042802"(identical protein binding)|rcsb pdb:5T9D|rcsb pdb:5V7K|rcsb pdb:5V7M|rcsb pdb:5ZUT|rcsb pdb:6CX2|rcsb pdb:6CX3|rcsb pdb:6CX4|rcsb pdb:6D0Q|rcsb pdb:6D0R|rcsb pdb:6E49|rcsb pdb:6W9W|rcsb pdb:6WAC|reactome:R-SCE-110312|reactome:R-SCE-110320|reactome:R-SCE-4615885|reactome:R-SCE-5358565|reactome:R-SCE-5655862|reactome:R-SCE-5656121|reactome:R-SCE-5656169|reactome:R-SCE-6782135|reactome:R-SCE-69091|reactome:R-SCE-69166|reactome:R-SCE-69183|reactome:R-SCE-8866654|rcsb pdb:5V7L	-	isoform-comment:No experimental confirmation available. May be due to competing acceptor splice site.	crc64:9B56C5851621DDDC	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:/GhmGv1GqwYuwjZWyCXHEd5UN3M9606	rogid:/+XSPV99OBBwBBC/nY0JiHaAeSI559292	intact-crc:67D5C8AACEAC1ED3|rigid:4EM3yzg8PzpDhnm9KhYccsP8+yo	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P10659	uniprotkb:P31153	intact:EBI-10789|ensemblfungi:YLR180W|uniprotkb:D6VYI4	intact:EBI-1050743|uniprotkb:Q53SP5|uniprotkb:A8K511|uniprotkb:D6W5L1|ensembl:ENSP00000303147|uniprotkb:B4DN45	psi-mi:metk1_yeast(display_long)|uniprotkb:SAM1(gene name)|psi-mi:SAM1(display_short)|uniprotkb:ETH10(gene name synonym)|uniprotkb:YLR180W(locus name)|uniprotkb:L9470.9(orf name)|uniprotkb:Methionine adenosyltransferase 1(gene name synonym)	psi-mi:metk2_human(display_long)|uniprotkb:Methionine adenosyltransferase 2(gene name synonym)|uniprotkb:Methionine adenosyltransferase II(gene name synonym)|uniprotkb:MAT2A(gene name)|psi-mi:MAT2A(display_short)|uniprotkb:AMS2(gene name synonym)|uniprotkb:MATA2(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549112|imex:IM-24995-2849	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YLR180W(gene)|ensemblfungi:YLR180W_mRNA(transcript)|go:"GO:0004478"(methionine adenosyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006555"(methionine metabolic process)|go:"GO:0006556"(S-adenosylmethionine biosynthetic process)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0046872"(metal ion binding)|interpro:IPR002133(S-adenosylmethionine synthetase)|interpro:IPR022628|interpro:IPR022629|interpro:IPR022630|interpro:IPR022631|interpro:IPR022636|reactome:R-SCE-156581|reactome:R-SCE-1614635|reactome:R-SCE-2408508|refseq:NP_013281.1|sgd:S000004170|mint:P10659|dip:DIP-6667N	refseq:NP_005902.1|rcsb pdb:5A1G|rcsb pdb:5A1I|rcsb pdb:5UGH|rcsb pdb:6FAJ|rcsb pdb:6FBN|rcsb pdb:6FBO|rcsb pdb:6FBP|rcsb pdb:6FCB|rcsb pdb:6FCD|rcsb pdb:6FWB|ensembl:ENSG00000168906(gene)|ensembl:ENST00000306434(transcript)|go:"GO:0004478"(methionine adenosyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006556"(S-adenosylmethionine biosynthetic process)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0034214"(protein hexamerization)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048269"(methionine adenosyltransferase complex)|go:"GO:0051291"(protein heterooligomerization)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR002133(S-adenosylmethionine synthetase)|rcsb pdb:6G6R|rcsb pdb:6P9V|rcsb pdb:6WKB|interpro:IPR022628|rcsb pdb:7BHR|rcsb pdb:7BHS|interpro:IPR022629|interpro:IPR022630|interpro:IPR022631|interpro:IPR022636|mint:P31153|rcsb pdb:2P02|rcsb pdb:4KTT|rcsb pdb:4KTV|rcsb pdb:4NDN|rcsb pdb:5A19|rcsb pdb:7BHT|rcsb pdb:7BHU|rcsb pdb:7BHV|rcsb pdb:7BHW|rcsb pdb:7BHX|rcsb pdb:7KCC|rcsb pdb:7KCE|rcsb pdb:7KCF|rcsb pdb:7KDA|rcsb pdb:7KDB|rcsb pdb:7L1A|reactome:R-HSA-156581	-	crc64:18F82FC809EE4706	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:PmIeDsMIksGSxihwmK1DqLFOItc559292	rogid:8QDKkbuHcvQtfzy2XkVjCKjTK709606	intact-crc:7D4442C465CC9346|rigid:CosvTDA0SKTdkrPi4EY0Y/z7Dm0	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P32458	uniprotkb:P23497-2	intact:EBI-4178|uniprotkb:D6VWP6|ensemblfungi:YJR076C	intact:EBI-6589365|ensembl:ENSP00000386404	psi-mi:cdc11_yeast(display_long)|uniprotkb:CDC11(gene name)|psi-mi:CDC11(display_short)|uniprotkb:PSL9(gene name synonym)|uniprotkb:YJR076C(locus name)|uniprotkb:J1833(orf name)	psi-mi:p23497-2(display_long)|uniprotkb:SP100(isoform synonym)|uniprotkb:SP100(gene name)|psi-mi:SP100(display_short)|uniprotkb:Nuclear dot-associated Sp100 protein(gene name synonym)|uniprotkb:Speckled 100 kDa(gene name synonym)|uniprotkb:SP100A(isoform synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549136|imex:IM-24995-2855	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012610.1|sgd:S000003837|dip:DIP-1656N|mint:P32458|ensemblfungi:YJR076C(gene)|ensemblfungi:YJR076C_mRNA(transcript)|go:"GO:0000144"(cellular bud neck septin ring)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000915"(actomyosin contractile ring assembly)|go:"GO:0000917"(division septum assembly)|go:"GO:0001400"(mating projection base)|go:"GO:0003924"(GTPase activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005619"(ascospore wall)|go:"GO:0005628"(prospore membrane)|go:"GO:0005876"(spindle microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0005935"(cellular bud neck)|go:"GO:0005940"(septin ring)|go:"GO:0010314"(phosphatidylinositol-5-phosphate binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030011"(maintenance of cell polarity)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0032160"(septin filament array)|go:"GO:0032186"(cellular bud neck septin ring organization)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042802"(identical protein binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0072687"(meiotic spindle)|go:"GO:0097271"(protein localization to bud neck)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|rcsb pdb:5AR1	intact:EBI-751145(isoform-parent)|uniprotkb:P23497-2(isoform-parent)|ensembl:ENSG00000067066(gene)|ensembl:ENST00000409341(transcript)	-	crc64:5CFFD4CD1F6C57D4	isoform-comment:Major isoform.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:KRcNMx6EOTmvHb+6u15UrVoyb3s559292	rogid:HrcogLANB///4vkSYtZ7OtzOb2k9606	intact-crc:DC026B8BBD38ACAA|rigid:VtSDFukPmOGOWGX4zAcA3fIbVI4	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P32354	uniprotkb:Q08379	intact:EBI-5965|uniprotkb:D6VVD7|ensemblfungi:YIL150C	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	psi-mi:mcm10_yeast(display_long)|uniprotkb:YIL150C(locus name)|uniprotkb:MCM10(gene name)|psi-mi:MCM10(display_short)|uniprotkb:DNA43(gene name synonym)|uniprotkb:Protein DNA43(gene name synonym)	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549132|imex:IM-24995-2854	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012116.1|sgd:S000001412|dip:DIP-1293N|mint:P32354|ensemblfungi:YIL150C(gene)|ensemblfungi:YIL150C_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005657"(replication fork)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006348"|go:"GO:0007049"(cell cycle)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0046872"(metal ion binding)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR015408(Zinc finger, Mcm10/DnaG-type)|interpro:IPR040184|reactome:R-SCE-68962	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2017/05/26	rogid:D2K/tLON/CnIcTTqkAQOdTZrRlg559292	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	intact-crc:1B6ACC06AB414A6D|rigid:+7ogc9529UUncV4bIF3BqIxIVco	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P31384	uniprotkb:Q96IQ6	intact:EBI-4396|uniprotkb:D6VPJ7|ensemblfungi:YAL021C	intact:EBI-10295632|intact:EBI-11525227	psi-mi:ccr4_yeast(display_long)|uniprotkb:CCR4(gene name)|psi-mi:CCR4(display_short)|uniprotkb:Carbon catabolite repressor protein 4(gene name synonym)|uniprotkb:Cytoplasmic deadenylase(gene name synonym)|uniprotkb:Glucose-repressible alcohol dehydrogenase transcriptional effector(gene name synonym)|uniprotkb:FUN27(orf name)|uniprotkb:YAL021C(locus name)	psi-mi:q96iq6_human(display_long)|uniprotkb:CCR4-associated factor 1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549120|imex:IM-24995-2851	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009381.1|sgd:S000000019|dip:DIP-2522N|mint:P31384|ensemblfungi:YAL021C(gene)|ensemblfungi:YAL021C_mRNA(transcript)|go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0004535"("poly(A)-specific ribonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0007089"(traversing start control point of mitotic cell cycle)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0046872"(metal ion binding)|go:"GO:0048478"(replication fork protection)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR005135(Endonuclease/exonuclease/phosphatase)|interpro:IPR025875|interpro:IPR032675|interpro:IPR036691|rcsb pdb:4B8C	interpro:IPR039636|interpro:IPR039637|refseq:NP_001309019.1|refseq:NP_001309020.1|refseq:NP_001309021.1|refseq:NP_001309022.1|interpro:IPR006941(Ribonuclease CAF1)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|refseq:NP_001309023.1|refseq:NP_001309024.1|refseq:NP_001309025.1|refseq:NP_001309026.1|refseq:NP_037486.2|go:"GO:0003676"(nucleic acid binding)|go:"GO:0004535"("poly(A)-specific ribonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006417"(regulation of translation)|go:"GO:0030014"(CCR4-NOT complex)|interpro:IPR036397	-	crc64:5CDB2E8FEDDBEF6F	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/17	rogid:f5gxp32WdxKuHQnE8O9/EhhA3Gw559292	rogid:nAvs1jhkGYxf7NZ456rj5p+imsI9606	intact-crc:DBB5B6426EF57322|rigid:1icdiwmRVXf6zQNT9XI8W2lxTWU	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:A0A0C4DGF1	uniprotkb:P32335	intact:EBI-10188476|ensembl:ENSP00000433657	intact:EBI-11318|uniprotkb:D6VYK4|ensemblfungi:YLR203C	psi-mi:a0a0c4dgf1_human(display_long)|uniprotkb:ZBTB32(gene name)|psi-mi:ZBTB32(display_short)	psi-mi:mss51_yeast(display_long)|uniprotkb:MSS51(gene name)|psi-mi:MSS51(display_short)|uniprotkb:YLR203C(locus name)|uniprotkb:L8167.17(orf name)|uniprotkb:Mitochondrial splicing suppressor protein 51(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549124|imex:IM-24995-2852	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|ensembl:ENSG00000011590(gene)|ensembl:ENST00000481182(transcript)|go:"GO:0042802"(identical protein binding)	ensemblfungi:YLR203C(gene)|ensemblfungi:YLR203C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0031314"(extrinsic component of mitochondrial inner membrane)|go:"GO:0033617"(mitochondrial cytochrome c oxidase assembly)|go:"GO:0045182"(translation regulator activity)|go:"GO:0070131"(positive regulation of mitochondrial translation)|interpro:IPR032717|interpro:IPR013272(YL1 nuclear, C-terminal)|sgd:S000004193|refseq:NP_013304.1|mint:P32335|dip:DIP-4602N	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:w3k7YT4kw/T+Xi5YBqGHSpHtwMM9606	rogid:ytfyoVVQ1W2FaXmytaIbaxZyYjE559292	intact-crc:DB083F25664EEAB3|rigid:9Z3qT3qmv5F1QZq68kZv2HPQHhk	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q08379	uniprotkb:P32335	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	intact:EBI-11318|uniprotkb:D6VYK4|ensemblfungi:YLR203C	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:mss51_yeast(display_long)|uniprotkb:MSS51(gene name)|psi-mi:MSS51(display_short)|uniprotkb:YLR203C(locus name)|uniprotkb:L8167.17(orf name)|uniprotkb:Mitochondrial splicing suppressor protein 51(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549128|imex:IM-24995-2853	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N	ensemblfungi:YLR203C(gene)|ensemblfungi:YLR203C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0031314"(extrinsic component of mitochondrial inner membrane)|go:"GO:0033617"(mitochondrial cytochrome c oxidase assembly)|go:"GO:0045182"(translation regulator activity)|go:"GO:0070131"(positive regulation of mitochondrial translation)|interpro:IPR032717|interpro:IPR013272(YL1 nuclear, C-terminal)|sgd:S000004193|refseq:NP_013304.1|mint:P32335|dip:DIP-4602N	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2017/05/26	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	rogid:ytfyoVVQ1W2FaXmytaIbaxZyYjE559292	intact-crc:29C50E83D39978A0|rigid:cV+qhCKhh9qPlAq6QOMTwpceMzI	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q08379	uniprotkb:P32464	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	intact:EBI-8859|ensemblfungi:YKL189W|uniprotkb:D6VX11	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:hym1_yeast(display_long)|uniprotkb:YKL189W(locus name)|uniprotkb:HYM1(gene name)|psi-mi:HYM1(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549152|imex:IM-24995-2859	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N	ensemblfungi:YKL189W(gene)|ensemblfungi:YKL189W_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0000920"(septum digestion after cytokinesis)|go:"GO:0005933"(cellular bud)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007118"(budding cell apical bud growth)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043332"(mating projection tip)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0044732"(mitotic spindle pole body)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013878(Mo25-like)|interpro:IPR016024(Armadillo-type fold)|reactome:R-SCE-6798695|refseq:NP_012732.1|sgd:S000001672|mint:P32464|dip:DIP-5425N	-	-	crc64:F48860754C892BA9	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2017/05/26	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	rogid:pOlQFFuYgFzmqf3ZGUVkBj9h7Uc559292	intact-crc:AB64E0AD92E726DC|rigid:TQTCCQDUSkfgGVImrqXaG4EjE+c	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:B0QYN7	uniprotkb:P32458	intact:EBI-11525376|ensembl:ENSP00000384361	intact:EBI-4178|uniprotkb:D6VWP6|ensemblfungi:YJR076C	psi-mi:b0qyn7_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)	psi-mi:cdc11_yeast(display_long)|uniprotkb:CDC11(gene name)|psi-mi:CDC11(display_short)|uniprotkb:PSL9(gene name synonym)|uniprotkb:YJR076C(locus name)|uniprotkb:J1833(orf name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549140|imex:IM-24995-2856	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_005255597.1|refseq:XP_005255598.1|refseq:XP_011520946.1|refseq:XP_011520947.1|ensembl:ENSG00000103275(gene)|ensembl:ENST00000402301(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0016740"(transferase activity)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313	refseq:NP_012610.1|sgd:S000003837|dip:DIP-1656N|mint:P32458|ensemblfungi:YJR076C(gene)|ensemblfungi:YJR076C_mRNA(transcript)|go:"GO:0000144"(cellular bud neck septin ring)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000915"(actomyosin contractile ring assembly)|go:"GO:0000917"(division septum assembly)|go:"GO:0001400"(mating projection base)|go:"GO:0003924"(GTPase activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005619"(ascospore wall)|go:"GO:0005628"(prospore membrane)|go:"GO:0005876"(spindle microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0005935"(cellular bud neck)|go:"GO:0005940"(septin ring)|go:"GO:0010314"(phosphatidylinositol-5-phosphate binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030011"(maintenance of cell polarity)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0032160"(septin filament array)|go:"GO:0032186"(cellular bud neck septin ring organization)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042802"(identical protein binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0072687"(meiotic spindle)|go:"GO:0097271"(protein localization to bud neck)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|rcsb pdb:5AR1	-	-	crc64:5CFFD4CD1F6C57D4	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:zMqQOA+nnCUquTIxAUwemkElTYI9606	rogid:KRcNMx6EOTmvHb+6u15UrVoyb3s559292	intact-crc:E81AB58DD0E45ABE|rigid:fb7aFDxlDpe3aiScIPewKqW1zHU	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P32463	uniprotkb:H0YCX2	intact:EBI-2113|uniprotkb:D6VX08|ensemblfungi:YKL192C	intact:EBI-11525431|ensembl:ENSP00000432463	psi-mi:acpm_yeast(display_long)|uniprotkb:ACP1(gene name)|psi-mi:ACP1(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 9.6 kDa subunit(gene name synonym)|uniprotkb:YKL192C(locus name)	psi-mi:h0ycx2_human(display_long)|uniprotkb:FAM193B(gene name)|psi-mi:FAM193B(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549144|imex:IM-24995-2857	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012729.1|sgd:S000001675|dip:DIP-3990N|mint:P32463|ensemblfungi:YKL192C(gene)|ensemblfungi:YKL192C_mRNA(transcript)|go:"GO:0000035"(acyl binding)|go:"GO:0000036"(acyl carrier activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0009107"(lipoate biosynthetic process)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0070469"(respirasome)|go:"GO:0099128"(mitochondrial iron-sulfur cluster assembly complex)|interpro:IPR003231("Acyl carrier protein (ACP)")|interpro:IPR006162(Phosphopantetheine attachment site)|interpro:IPR009081(Acyl carrier protein-like)|interpro:IPR036736|reactome:R-SCE-389661|reactome:R-SCE-77289	ensembl:ENSG00000146067(gene)|ensembl:ENST00000524677(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0016607"(nuclear speck)|interpro:IPR029717|interpro:IPR029722|interpro:IPR031802	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:u1Dnj7iL+Ty5d20JWalQsAUxAS4559292	rogid:aMr6uO1ZOLPg/THCfO6xLJWkO7Y9606	intact-crc:1E7E73A57339EF92|rigid:re4U2XvrEj12Jkyq5nuQJkV7lmM	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O43281-2	uniprotkb:P32463	intact:EBI-11525448|ensembl:ENSP00000340607	intact:EBI-2113|uniprotkb:D6VX08|ensemblfungi:YKL192C	psi-mi:o43281-2(display_long)|uniprotkb:CASS3(gene name synonym)|uniprotkb:Cas scaffolding protein family member 3(gene name synonym)|uniprotkb:EFS(gene name)|psi-mi:EFS(display_short)	psi-mi:acpm_yeast(display_long)|uniprotkb:ACP1(gene name)|psi-mi:ACP1(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 9.6 kDa subunit(gene name synonym)|uniprotkb:YKL192C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549148|imex:IM-24995-2858	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-718488(isoform-parent)|ensembl:ENSG00000100842(gene)|ensembl:ENST00000351354(transcript)|uniprotkb:O43281-2(isoform-parent)	refseq:NP_012729.1|sgd:S000001675|dip:DIP-3990N|mint:P32463|ensemblfungi:YKL192C(gene)|ensemblfungi:YKL192C_mRNA(transcript)|go:"GO:0000035"(acyl binding)|go:"GO:0000036"(acyl carrier activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0009107"(lipoate biosynthetic process)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0070469"(respirasome)|go:"GO:0099128"(mitochondrial iron-sulfur cluster assembly complex)|interpro:IPR003231("Acyl carrier protein (ACP)")|interpro:IPR006162(Phosphopantetheine attachment site)|interpro:IPR009081(Acyl carrier protein-like)|interpro:IPR036736|reactome:R-SCE-389661|reactome:R-SCE-77289	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:JdV6uL2+FglKvl/B+OVXk/eIIKQ9606	rogid:u1Dnj7iL+Ty5d20JWalQsAUxAS4559292	intact-crc:C7153BC7CF9BE6B2|rigid:FWmc9lAegRJYcR77EXv33eoE0jk	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q7Z6G3-2	uniprotkb:P32502	intact:EBI-10172876|ensembl:ENSP00000457354|intact:EBI-14062040	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:q7z6g3-2(display_long)|uniprotkb:EFCBP2(gene name synonym)|uniprotkb:Neuronal calcium-binding protein 2(gene name synonym)|uniprotkb:Synaptotagmin-interacting protein 2(gene name synonym)|uniprotkb:NECAB2(gene name)|psi-mi:NECAB2(display_short)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549168|imex:IM-24995-2863	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000103154(gene)|ensembl:ENST00000565691(transcript)|uniprotkb:Q7Z6G3-2(isoform-parent)|intact:EBI-950070(isoform-parent)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731	-	-	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:4S7oIx6h+mKzV3EPxqcfMNqaNko9606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:FBBFBCB58B16AEDF|rigid:83Cnms/xtYhuLT9dx6N+G4rH+m0	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O14879	uniprotkb:P32464	intact:EBI-745127|uniprotkb:Q99634|uniprotkb:Q9BSK7|ensembl:ENSP00000360876|ensembl:ENSP00000360883|ensembl:ENSP00000505987	intact:EBI-8859|ensemblfungi:YKL189W|uniprotkb:D6VX11	psi-mi:ifit3_human(display_long)|uniprotkb:ISG-60(gene name synonym)|uniprotkb:CIG49(gene name synonym)|uniprotkb:Retinoic acid-induced gene G protein(gene name synonym)|uniprotkb:Interferon-induced protein with tetratricopeptide repeats 4(gene name synonym)|uniprotkb:Interferon-induced 60 kDa protein(gene name synonym)|uniprotkb:IFIT3(gene name)|psi-mi:IFIT3(display_short)|uniprotkb:IFI60(gene name synonym)|uniprotkb:IFIT4(gene name synonym)|uniprotkb:CIG-49(gene name synonym)|uniprotkb:ISG60(gene name synonym)	psi-mi:hym1_yeast(display_long)|uniprotkb:YKL189W(locus name)|uniprotkb:HYM1(gene name)|psi-mi:HYM1(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549156|imex:IM-24995-2860	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001026853.1|refseq:NP_001540.2|ensembl:ENSG00000119917(gene)|ensembl:ENST00000371811(transcript)|ensembl:ENST00000371818(transcript)|ensembl:ENST00000679781(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009615"(response to virus)|go:"GO:0035457"(cellular response to interferon-alpha)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR024122|mint:O14879|rcsb pdb:6C6K|reactome:R-HSA-909733|dip:DIP-37890N	ensemblfungi:YKL189W(gene)|ensemblfungi:YKL189W_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0000920"(septum digestion after cytokinesis)|go:"GO:0005933"(cellular bud)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007118"(budding cell apical bud growth)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043332"(mating projection tip)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0044732"(mitotic spindle pole body)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013878(Mo25-like)|interpro:IPR016024(Armadillo-type fold)|reactome:R-SCE-6798695|refseq:NP_012732.1|sgd:S000001672|mint:P32464|dip:DIP-5425N	-	-	crc64:F48860754C892BA9	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:K8uDHfKNx0YBgTkwpEaRKvx24/k9606	rogid:pOlQFFuYgFzmqf3ZGUVkBj9h7Uc559292	intact-crc:A934C0EFB1ACED84|rigid:1oLkIlyzqwp89jwljG2iTwKN9ww	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P14373	uniprotkb:P32464	intact:EBI-719493|uniprotkb:A2BE15|uniprotkb:Q5RJA8|uniprotkb:Q5ST26|uniprotkb:Q6LA73|uniprotkb:Q6NXR9|uniprotkb:Q9BZY6|uniprotkb:Q9UJL3|ensembl:ENSP00000383555|ensembl:ENSP00000392787|ensembl:ENSP00000405229|ensembl:ENSP00000414793|ensembl:ENSP00000366404	intact:EBI-8859|ensemblfungi:YKL189W|uniprotkb:D6VX11	psi-mi:tri27_human(display_long)|uniprotkb:TRIM27(gene name)|psi-mi:TRIM27(display_short)|uniprotkb:RNF76(gene name synonym)|uniprotkb:RFP(gene name synonym)|uniprotkb:Ret finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 27(gene name synonym)|uniprotkb:RING finger protein 76(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM27(gene name synonym)	psi-mi:hym1_yeast(display_long)|uniprotkb:YKL189W(locus name)|uniprotkb:HYM1(gene name)|psi-mi:HYM1(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549160|imex:IM-24995-2861	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006501.1|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0090281"(negative regulation of calcium ion import)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR020457|interpro:IPR035791|interpro:IPR043136|mint:P14373|reactome:R-HSA-3232142|reactome:R-HSA-9635465|reactome:R-HSA-8948751|ensembl:ENSG00000204713(gene)|ensembl:ENSG00000215641(gene)|ensembl:ENSG00000229006(gene)|ensembl:ENSG00000234495(gene)|ensembl:ENSG00000237071(gene)|ensembl:ENST00000377199(transcript)|ensembl:ENST00000400720(transcript)|ensembl:ENST00000431123(transcript)|ensembl:ENST00000435528(transcript)|ensembl:ENST00000437160(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001650"(fibrillar center)|go:"GO:0002820"(negative regulation of adaptive immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)	ensemblfungi:YKL189W(gene)|ensemblfungi:YKL189W_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0000920"(septum digestion after cytokinesis)|go:"GO:0005933"(cellular bud)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007118"(budding cell apical bud growth)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043332"(mating projection tip)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0044732"(mitotic spindle pole body)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013878(Mo25-like)|interpro:IPR016024(Armadillo-type fold)|reactome:R-SCE-6798695|refseq:NP_012732.1|sgd:S000001672|mint:P32464|dip:DIP-5425N	-	-	crc64:F48860754C892BA9	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:dsfH5OUghD8KSaTz1SFw9OYVTK49606	rogid:pOlQFFuYgFzmqf3ZGUVkBj9h7Uc559292	intact-crc:DDDBEE7B2170A759|rigid:2igrLlIUhR+ddAP5LUqSOBOq6IE	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P26641	uniprotkb:P32497	intact:EBI-351467|uniprotkb:Q6PJ62|uniprotkb:Q6PK31|uniprotkb:Q96CU2|uniprotkb:Q9P196|intact:EBI-2321928|uniprotkb:B4DTG2|ensembl:ENSP00000331901	intact:EBI-8965|ensemblfungi:YMR309C|uniprotkb:D6W0D6	psi-mi:ef1g_human(display_long)|uniprotkb:PRO1608(orf name)|uniprotkb:EEF1G(gene name)|psi-mi:EEF1G(display_short)|uniprotkb:EF1G(gene name synonym)|uniprotkb:eEF-1B gamma(gene name synonym)	psi-mi:eif3c_yeast(display_long)|uniprotkb:NIP1(gene name)|psi-mi:NIP1(display_short)|uniprotkb:YMR309C(locus name)|uniprotkb:YM9924.01C(orf name)|uniprotkb:YM9952.11C(orf name)|uniprotkb:Eukaryotic translation initiation factor 3 93 kDa subunit(gene name synonym)|uniprotkb:Nuclear transport protein NIP1(gene name synonym)|uniprotkb:Translation initiation factor eIF3, p93 subunit(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549164|imex:IM-24995-2862	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001395.1|ensembl:ENSG00000254772(gene)|ensembl:ENST00000329251(transcript)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006414"(translational elongation)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001662(Translation elongation factor EF1B, gamma chain, conserved)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR036249|interpro:IPR036282|interpro:IPR036433|interpro:IPR040079|mint:P26641|rcsb pdb:1PBU|rcsb pdb:5DQS|rcsb pdb:5JPO|reactome:R-HSA-156842|dip:DIP-32516N	go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|ensemblfungi:YMR309C(gene)|ensemblfungi:YMR309C_mRNA(transcript)|go:"GO:0006413"(translational initiation)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0043614"(multi-eIF complex)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR008905(Eukaryotic translation initiation factor 3 subunit 8, N-terminal)|interpro:IPR027516|rcsb pdb:3JAP|rcsb pdb:4U1C|rcsb pdb:5H7U|rcsb pdb:6FYX|rcsb pdb:6FYY|rcsb pdb:6GSM|rcsb pdb:6GSN|rcsb pdb:6ZCE|rcsb pdb:6ZU9|reactome:R-SCE-156827|reactome:R-SCE-72649|reactome:R-SCE-72695|reactome:R-SCE-72702|refseq:NP_014040.1|sgd:S000004926|mint:P32497|dip:DIP-1470N	-	-	crc64:EE05097C44C45A4C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:biVN96umeEdPm/wvPN4VwbSRHTs9606	rogid:D2B5DHNCbowAIRjWdoxAkeP/CXk559292	intact-crc:D75981CBFB871B79|rigid:UDC3Tvp+dHT39OFxJPk6nv7LHOc	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:I6L8A6	uniprotkb:P32502	intact:EBI-11525639|ensembl:ENSP00000354024	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:i6l8a6_human(display_long)|uniprotkb:DNA endonuclease RBBP8(gene name synonym)|uniprotkb:RBBP8(gene name)|psi-mi:RBBP8(display_short)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549188|imex:IM-24995-2868	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000101773(gene)|ensembl:ENST00000360790(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003677"(DNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0010792"(DNA double-strand break processing involved in repair via single-strand annealing)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|interpro:IPR013882(DNA repair protein Sae2)|interpro:IPR019518|interpro:IPR033316|interpro:IPR033594	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731	-	-	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:GHiZbuwZR+0GRaqg0vt6Dsg4pCk9606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:EE2F86C1F42DB9F7|rigid:9aDIyPR3htM3T7hxoOi2T6lRyt0	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O15156-2	uniprotkb:P32502	intact:EBI-11522250|ensembl:ENSP00000406286	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:o15156-2(display_long)|uniprotkb:ZBTB7B(gene name)|psi-mi:ZBTB7B(display_short)|uniprotkb:Krueppel-related zinc finger protein cKrox(gene name synonym)|uniprotkb:T-helper-inducing POZ/Krueppel-like factor(gene name synonym)|uniprotkb:ZBTB15(gene name synonym)|uniprotkb:ZFP67(gene name synonym)|uniprotkb:ZNF857B(gene name synonym)|uniprotkb:Zinc finger and BTB domain-containing protein 15(gene name synonym)|uniprotkb:Zinc finger protein 67 homolog(gene name synonym)|uniprotkb:Zinc finger protein 857B(gene name synonym)|uniprotkb:Zinc finger protein Th-POK(gene name synonym)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549184|imex:IM-24995-2867	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-740434(isoform-parent)|ensembl:ENSG00000160685(gene)|ensembl:ENST00000417934(transcript)|uniprotkb:O15156-2(isoform-parent)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731	-	isoform-comment:No experimental confirmation available.	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:41NEFYyprTXI+fOHVFh78TPKF289606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:34F4E678DDD1E524|rigid:/+UmWdQzSLdY3ig1erzXeqIHwFY	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P32502	uniprotkb:P04271	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	intact:EBI-458391|ensembl:ENSP00000291700|ensembl:ENSP00000380769|uniprotkb:D3DSN6	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:s100b_human(display_long)|uniprotkb:S100B(gene name)|psi-mi:S100B(display_short)|uniprotkb:S100 calcium-binding protein B(gene name synonym)|uniprotkb:S-100 protein subunit beta(gene name synonym)|uniprotkb:S-100 protein beta chain(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549172|imex:IM-24995-2864	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731	ensembl:ENSG00000160307(gene)|ensembl:ENST00000291700(transcript)|ensembl:ENST00000397648(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007409"(axonogenesis)|go:"GO:0007417"(central nervous system development)|go:"GO:0007611"(learning or memory)|go:"GO:0007613"(memory)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0031643"(positive regulation of myelination)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044548"(S100 protein binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0048168"(regulation of neuronal synaptic plasticity)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048708"(astrocyte differentiation)|go:"GO:0050786"(RAGE receptor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0051597"(response to methylmercury)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:2001015"(negative regulation of skeletal muscle cell differentiation)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR018247|interpro:IPR028481|mint:P04271|rcsb pdb:1MQ1|rcsb pdb:1UWO|rcsb pdb:2H61|rcsb pdb:2M49|rcsb pdb:2PRU|rcsb pdb:3CZT|rcsb pdb:3D0Y|rcsb pdb:3D10|rcsb pdb:3HCM|rcsb pdb:4XYN|rcsb pdb:5CSF|rcsb pdb:5CSI|rcsb pdb:5CSJ|rcsb pdb:5CSN|rcsb pdb:5D7F|go:"GO:0051384"(response to glucocorticoid)|reactome:R-HSA-1251985|reactome:R-HSA-445989|reactome:R-HSA-879415|reactome:R-HSA-933542|refseq:NP_006263.1|refseq:XP_016883913.1	-	crc64:A5409FAF1594854C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	rogid:e6p9zHV5sa8+lIZgYW1aiAAfq3s9606	intact-crc:CFDFD9956B3F4246|rigid:R0s2qnF0R4cHOZOdmXpPr9Eil5U	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P32502	uniprotkb:O76083-2	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	intact:EBI-11524542|ensembl:ENSP00000335242	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:o76083-2(display_long)|uniprotkb:PDE9A(gene name)|psi-mi:PDE9A(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549176|imex:IM-24995-2865	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731	intact:EBI-742764(isoform-parent)|ensembl:ENSG00000160191(gene)|ensembl:ENST00000335512(transcript)|uniprotkb:O76083-2(isoform-parent)	-	crc64:A5409FAF1594854C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	rogid:nTzgeYGOwTM/7VJUgxSnlnDiCFo9606	intact-crc:46886E7CE33786D6|rigid:K4ak8/bIDA6IYLzdcaWwFmmTfPg	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P32502	uniprotkb:O14964	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	intact:EBI-740220|uniprotkb:Q9NR36|ensembl:ENSP00000331201|ensembl:ENSP00000504106	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:hgs_human(display_long)|uniprotkb:Protein pp110(gene name synonym)|uniprotkb:Hrs(gene name synonym)|uniprotkb:HGS(gene name)|psi-mi:HGS(display_short)|uniprotkb:HRS(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549180|imex:IM-24995-2866	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731	refseq:NP_004703.1|dip:DIP-29050N|ensembl:ENSG00000185359(gene)|ensembl:ENST00000329138(transcript)|ensembl:ENST00000676546(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0007165"(signal transduction)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010324"(membrane invagination)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010642"(negative regulation of platelet-derived growth factor receptor signaling pathway)|go:"GO:0016197"(endosomal transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032585"(multivesicular body membrane)|go:"GO:0033565"(ESCRT-0 complex)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043405"(regulation of MAP kinase activity)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072657"(protein localization to membrane)|go:"GO:0097013"(phagocytic vesicle lumen)|go:"GO:1903543"(positive regulation of exosomal secretion)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR002014(VHS)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017073(Ubiquitin binding protein, Hrs/VPS27)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR024641|mint:O14964|rcsb pdb:2D3G|rcsb pdb:3F1I|rcsb pdb:3OBQ|rcsb pdb:3ZYQ|rcsb pdb:4AVX|reactome:R-HSA-182971|reactome:R-HSA-432720|reactome:R-HSA-5689880|reactome:R-HSA-6807004|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8875360|reactome:R-HSA-9013420|reactome:R-HSA-917729|reactome:R-HSA-9635644|reactome:R-HSA-9636383|reactome:R-HSA-9706019	-	crc64:A5409FAF1594854C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	rogid:z/AnREuqEpyJ9/Zj6JFCJCJem1I9606	intact-crc:02C6B24431215D70|rigid:i5XcpStCfjaiDLc3pfO7yC2tQhI	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P32502	uniprotkb:O14641	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	intact:EBI-740850|ensembl:ENSP00000005340|uniprotkb:Q53XM0|uniprotkb:D3DTN3	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:dvl2_human(display_long)|uniprotkb:DSH homolog 2(gene name synonym)|uniprotkb:DVL2(gene name)|psi-mi:DVL2(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549208|imex:IM-24995-2873	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731	refseq:NP_004413.1|ensembl:ENSG00000004975(gene)|ensembl:ENST00000005340(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005109"(frizzled binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0007507"(heart development)|go:"GO:0016235"(aggresome)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044340"(canonical Wnt signaling pathway involved in regulation of cell proliferation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0150012"(positive regulation of neuron projection arborization)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008341(Dishevelled-2 region)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:O14641|rcsb pdb:2REY|rcsb pdb:3CBX|rcsb pdb:3CBY|rcsb pdb:3CBZ|rcsb pdb:3CC0|rcsb pdb:4WIP|rcsb pdb:5LNP|rcsb pdb:5SUY|rcsb pdb:5SUZ|rcsb pdb:6IW3|rcsb pdb:6JCK|reactome:R-HSA-201681|reactome:R-HSA-201688|reactome:R-HSA-2028269|reactome:R-HSA-4086400|reactome:R-HSA-4608870|reactome:R-HSA-4641258|reactome:R-HSA-4641262|reactome:R-HSA-5099900|reactome:R-HSA-5368598|reactome:R-HSA-5663220|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9673324|ensembl:ENSP00000005340|dip:DIP-34433N	-	crc64:A5409FAF1594854C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	rogid:2Vdc8oRnT4Mz/j+EXQXrL3AszOc9606	intact-crc:9B4A03CC7BA03D10|rigid:pm9EJtyO2bHhLP88C1nUq0TAN68	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O75506	uniprotkb:P32502	intact:EBI-748664|uniprotkb:Q7Z5Z3|uniprotkb:Q53XA8|ensembl:ENSP00000392896|ensembl:ENSP00000458007	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:hsbp1_human(display_long)|uniprotkb:Nasopharyngeal carcinoma-associated antigen 13(gene name synonym)|uniprotkb:HSBP1(gene name)|psi-mi:HSBP1(display_short)|uniprotkb:HSF1BP(gene name synonym)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549204|imex:IM-24995-2872	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001528.1|interpro:IPR009643(Heat shock factor binding 1)|rcsb pdb:3CI9|reactome:R-HSA-3371511|reactome:R-HSA-3371568|reactome:R-HSA-3371571|ensembl:ENSG00000230989(gene)|ensembl:ENST00000433866(transcript)|ensembl:ENST00000570259(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006936"(muscle contraction)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0070370"(cellular heat acclimation)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731	-	-	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:3JML7OxHIw8M91ARKPfOhJ9kVbk9606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:3A0CDAA995BD3338|rigid:dyaEbB+dUfXqlZ1ueee42GVMNUY	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P32502	uniprotkb:P07910-2	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	intact:EBI-5280084|ensembl:ENSP00000442816|ensembl:ENSP00000450544|ensembl:ENSP00000450725|ensembl:ENSP00000451176	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:p07910-2(display_long)|uniprotkb:HNRNPC(gene name)|psi-mi:HNRNPC(display_short)|uniprotkb:HNRPC(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549192|imex:IM-24995-2869	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731	uniprotkb:P07910-2(isoform-parent)|intact:EBI-357966(isoform-parent)|ensembl:ENSG00000092199(gene)|ensembl:ENST00000430246(transcript)|ensembl:ENST00000553300(transcript)|ensembl:ENST00000554969(transcript)|ensembl:ENST00000556897(transcript)	-	crc64:A5409FAF1594854C	isoform-comment:Contains a phosphoserine at position 107. Contains a phosphoserine at position 108.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	rogid:r7AhGozE3aHdynLr8DrXPRtOuyI9606	intact-crc:1BF9355F87EBE816|rigid:1cqi50rFIN9YGgs3/g3Rad18Oyk	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P32502	uniprotkb:P08727	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	intact:EBI-742756|uniprotkb:Q5XG83|uniprotkb:Q6NW33|uniprotkb:Q7L5M9|uniprotkb:Q96A53|uniprotkb:Q96FV1|uniprotkb:Q9BYF9|uniprotkb:Q9P1Y4|uniprotkb:B2R874|ensembl:ENSP00000355124	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:k1c19_human(display_long)|uniprotkb:Cytokeratin-19(gene name synonym)|uniprotkb:Keratin-19(gene name synonym)|uniprotkb:KRT19(gene name)|psi-mi:KRT19(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549196|imex:IM-24995-2870	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731	refseq:NP_002267.2|ensembl:ENSG00000171345(gene)|ensembl:ENST00000361566(transcript)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0030018"(Z disc)|go:"GO:0042383"(sarcolemma)|go:"GO:0043034"(costamere)|go:"GO:0043627"(response to estrogen)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0060706"(cell differentiation involved in embryonic placenta development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071944"(cell periphery)|go:"GO:1990357"(terminal web)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR039008|mint:P08727|reactome:R-HSA-6805567|reactome:R-HSA-6809371|dip:DIP-35655N	-	crc64:A5409FAF1594854C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	rogid:fqsG2nghpcmTtI39LiYVLNYuFIA9606	intact-crc:D558EE8FF0F329C1|rigid:GRI60gRVRUUKPM4dUxsitr4Uytg	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P14174	uniprotkb:P32502	intact:EBI-372712|uniprotkb:A5Z1R8|uniprotkb:B2R4S3|uniprotkb:Q6FHV0|uniprotkb:Q2V4Y5|ensembl:ENSP00000215754|ensembl:ENSP00000482779	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:mif_human(display_long)|uniprotkb:MIF(gene name)|psi-mi:MIF(display_short)|uniprotkb:MMIF(gene name synonym)|uniprotkb:GLIF(gene name synonym)|uniprotkb:Phenylpyruvate tautomerase(gene name synonym)|uniprotkb:Glycosylation-inhibiting factor(gene name synonym)|uniprotkb:L-dopachrome tautomerase(gene name synonym)|uniprotkb:L-dopachrome isomerase(gene name synonym)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549200|imex:IM-24995-2871	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002406.1|ensembl:ENST00000215754(transcript)|ensembl:ENST00000613839(transcript)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0004167"(dopachrome isomerase activity)|go:"GO:0005125"(cytokine activity)|go:"GO:0005126"(cytokine receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|ensembl:ENSG00000276701(gene)|go:"GO:0006954"(inflammatory response)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0009986"(cell surface)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010739"(positive regulation of protein kinase A signaling)|go:"GO:0010760"(negative regulation of macrophage chemotaxis)|go:"GO:0019752"(carboxylic acid metabolic process)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031982"(vesicle)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042056"(chemoattractant activity)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043030"(regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|ensembl:ENSG00000240972(gene)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045087"(innate immune response)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0050178"(phenylpyruvate tautomerase activity)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070207"(protein homotrimerization)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0090344"(negative regulation of cell aging)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR001398(Macrophage migration inhibitory factor)|interpro:IPR014347(Tautomerase)|interpro:IPR019829|mint:P14174|rcsb pdb:1CGQ|rcsb pdb:1GCZ|rcsb pdb:1GD0|rcsb pdb:1GIF|rcsb pdb:1LJT|rcsb pdb:1MIF|rcsb pdb:1P1G|rcsb pdb:2OOH|rcsb pdb:2OOW|rcsb pdb:2OOZ|rcsb pdb:3B9S|rcsb pdb:3CE4|rcsb pdb:3DJH|rcsb pdb:3DJI|rcsb pdb:3HOF|rcsb pdb:3IJG|rcsb pdb:3IJJ|rcsb pdb:3JSF|rcsb pdb:3JSG|rcsb pdb:3JTU|rcsb pdb:3L5P|rcsb pdb:3L5R|rcsb pdb:3L5S|rcsb pdb:3L5T|rcsb pdb:3L5U|rcsb pdb:3L5V|rcsb pdb:3SMB|rcsb pdb:3SMC|rcsb pdb:3U18|rcsb pdb:3WNR|rcsb pdb:3WNS|rcsb pdb:3WNT|rcsb pdb:4ETG|rcsb pdb:4EUI|rcsb pdb:4EVG|rcsb pdb:4F2K|rcsb pdb:4GRN|rcsb pdb:4GRO|rcsb pdb:4GRP|rcsb pdb:4GRQ|rcsb pdb:4GRR|rcsb pdb:4GRU|rcsb pdb:4GUM|rcsb pdb:4K9G|rcsb pdb:4OSF|rcsb pdb:4OYQ|rcsb pdb:4P01|rcsb pdb:4P0H|rcsb pdb:4PKK|rcsb pdb:4PKZ|rcsb pdb:4PLU|rcsb pdb:4TRF|rcsb pdb:4TRU|rcsb pdb:4WR8|rcsb pdb:4WRB|rcsb pdb:4XX7|rcsb pdb:4XX8|rcsb pdb:4Z15|rcsb pdb:4Z1T|rcsb pdb:4Z1U|rcsb pdb:5B4O|rcsb pdb:5BS9|rcsb pdb:5BSC|rcsb pdb:5BSI|rcsb pdb:5BSJ|rcsb pdb:5EIZ|rcsb pdb:5HVS|rcsb pdb:5HVT|rcsb pdb:5HVV|rcsb pdb:5J7P|rcsb pdb:5J7Q|rcsb pdb:5UMJ|rcsb pdb:5UMK|rcsb pdb:5UZY|rcsb pdb:5V70|rcsb pdb:5V73|rcsb pdb:5XEJ|rcsb pdb:1CA7|rcsb pdb:6B1C|rcsb pdb:6B1K|rcsb pdb:6B2C|rcsb pdb:6BG6|rcsb pdb:6BG7|rcsb pdb:6CB5|rcsb pdb:6CBF|rcsb pdb:6CBG|rcsb pdb:6FVE|rcsb pdb:6FVH|rcsb pdb:6OY8|rcsb pdb:6OYB|rcsb pdb:6OYE|rcsb pdb:6OYG|rcsb pdb:6PEG|reactome:R-HSA-202733|reactome:R-HSA-6798695|reactome:R-HSA-8950505|rcsb pdb:6CBH|dip:DIP-31137N	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731	-	-	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Vk+Sfaz5c59y8dKKJ4Qn+7fjwvQ9606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:D77AB0FA7E96AC69|rigid:e777KalAyYVYYod1TcXejrZ/0h0	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:G5E962	uniprotkb:P32502	intact:EBI-11525615|ensembl:ENSP00000328177	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:g5e962_human(display_long)|uniprotkb:hCG_1644200(orf name)|uniprotkb:MAGEA11(gene name)|psi-mi:MAGEA11(display_short)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549220|imex:IM-24995-2876	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001011544.1|ensembl:ENSG00000185247(gene)|ensembl:ENST00000333104(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016604"(nuclear body)|interpro:IPR002190(MAGE protein)|interpro:IPR021072|interpro:IPR030099|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731	-	-	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:sVB0aA6yibWUx/d2SE+pwpKKgtI9606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:2658A677A11181BD|rigid:6aq7Xa/T42Sl2M+Fq5wpd1aNTio	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O60232	uniprotkb:P32502	intact:EBI-741415|ensembl:ENSP00000312318	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:znrd2_human(display_long)|uniprotkb:ZNRD2(gene name)|psi-mi:ZNRD2(display_short)|uniprotkb:Autoantigen p27(gene name synonym)|uniprotkb:SSSCA1(gene name synonym)|uniprotkb:Sjoegren syndrome/scleroderma autoantigen 1(gene name synonym)|uniprotkb:Zinc ribbon domain-containing protein 2(gene name synonym)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549216|imex:IM-24995-2875	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006387.1|ensembl:ENSG00000173465(gene)|ensembl:ENST00000309328(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0051301"(cell division)|interpro:IPR009563(Sjogrens syndrome scleroderma autoantigen 1)|rcsb pdb:6HCZ	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731	-	-	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Uou80pZneoL39/0YYzb1TAbiB2I9606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:45615942879761D9|rigid:Mv4bbKj+10EcTY9SVZ16eZ7Fty4	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P19012	uniprotkb:P32502	intact:EBI-739566|uniprotkb:Q53XV8|uniprotkb:Q9BUG4|uniprotkb:B3KQY1|uniprotkb:B3KRA2|uniprotkb:E0CX14|ensembl:ENSP00000254043|ensembl:ENSP00000377546	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:k1c15_human(display_long)|uniprotkb:KRT15(gene name)|psi-mi:KRT15(display_short)|uniprotkb:KRTB(gene name synonym)|uniprotkb:Cytokeratin-15(gene name synonym)|uniprotkb:Keratin-15(gene name synonym)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549224|imex:IM-24995-2877	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002266.2|ensembl:ENSG00000171346(gene)|ensembl:ENST00000254043(transcript)|ensembl:ENST00000393976(transcript)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0008544"(epidermis development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097110"(scaffold protein binding)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR039008|mint:P19012|reactome:R-HSA-6805567|reactome:R-HSA-6809371	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731	-	-	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:WrZQBYQvrWcfrR5ojWXrXp6spPE9606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:3EBC16B0B175FA16|rigid:0gvENk/O19qCoFW25bO+8k1LDdA	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O15217	uniprotkb:P32502	intact:EBI-752440|uniprotkb:Q5T7Q8|uniprotkb:Q9BX18|uniprotkb:Q9H414|uniprotkb:B2RD15|uniprotkb:Q6P4G1|ensembl:ENSP00000359998|ensembl:ENSP00000360002	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:gsta4_human(display_long)|uniprotkb:Glutathione S-transferase A4-4(gene name synonym)|uniprotkb:GST class-alpha member 4(gene name synonym)|uniprotkb:GSTA4(gene name)|psi-mi:GSTA4(display_short)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549228|imex:IM-24995-2878	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001503.1|refseq:XP_005249092.1|ensembl:ENSG00000170899(gene)|ensembl:ENST00000370959(transcript)|ensembl:ENST00000370963(transcript)|go:"GO:0004364"(glutathione transferase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0006805"(xenobiotic metabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|interpro:IPR003080(Glutathione S-transferase, alpha class)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR036249|interpro:IPR036282|interpro:IPR040079|rcsb pdb:1GUL|rcsb pdb:1GUM|rcsb pdb:3IK7|reactome:R-HSA-156590	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731	-	-	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:9yVcqmJL64S0kxOW5RJWbOJ25bo9606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:3F817A29677C0FA3|rigid:vivFJzLRywr+nlr9ldQiyJabTCY	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O43809	uniprotkb:P32502	intact:EBI-355720|uniprotkb:Q6IB85|uniprotkb:Q6NE84|ensembl:ENSP00000300291	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:cpsf5_human(display_long)|uniprotkb:NUDT21(gene name)|psi-mi:NUDT21(display_short)|uniprotkb:CFIM25(gene name synonym)|uniprotkb:CPSF25(gene name synonym)|uniprotkb:CPSF5(gene name synonym)|uniprotkb:Cleavage and polyadenylation specificity factor 25 kDa subunit(gene name synonym)|uniprotkb:Nucleoside diphosphate-linked moiety X motif 21(gene name synonym)|uniprotkb:Cleavage factor Im complex 25 kDa subunit(gene name synonym)|uniprotkb:Nudix hydrolase 21(gene name synonym)|uniprotkb:Pre-mRNA cleavage factor Im 68 kDa subunit(gene name synonym)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549212|imex:IM-24995-2874	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_008937.1|ensembl:ENSG00000167005(gene)|ensembl:ENST00000300291(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0005849"(mRNA cleavage factor complex)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0006397"(mRNA processing)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0031439"(positive regulation of mRNA cleavage)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0042382"(paraspeckles)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051290"(protein heterotetramerization)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|go:"GO:0110104"(mRNA alternative polyadenylation)|go:"GO:1900365"(positive regulation of mRNA polyadenylation)|go:"GO:1990120"(messenger ribonucleoprotein complex assembly)|go:"GO:2000738"(positive regulation of stem cell differentiation)|go:"GO:2000975"(positive regulation of pro-B cell differentiation)|interpro:IPR000086(NUDIX hydrolase, core)|interpro:IPR015797(NUDIX)|interpro:IPR016706(Cleavage and polyadenylation specificity factor, 25 kDa subunit)|mint:O43809|rcsb pdb:2CL3|rcsb pdb:2J8Q|rcsb pdb:3BAP|rcsb pdb:3BHO|rcsb pdb:3MDG|rcsb pdb:3MDI|rcsb pdb:3N9U|rcsb pdb:3P5T|rcsb pdb:3P6Y|rcsb pdb:3Q2S|rcsb pdb:3Q2T|rcsb pdb:5R4P|rcsb pdb:5R4Q|rcsb pdb:5R4R|rcsb pdb:5R4S|rcsb pdb:5R4T|rcsb pdb:5R4U|rcsb pdb:5R64|rcsb pdb:5R65|rcsb pdb:5R66|rcsb pdb:5R67|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-77595|dip:DIP-42502N	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731	-	-	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Acad4mYVuS+Eox+X2CH8PYUkGAA9606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:BD03352581441F21|rigid:BP13JVI+4PVMBrwgCeg4x1bZzTw	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P00492	uniprotkb:P32502	intact:EBI-748210|uniprotkb:A6NHF0|uniprotkb:B2R8M9|ensembl:ENSP00000298556	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:hprt_human(display_long)|uniprotkb:HPRT1(gene name)|psi-mi:HPRT1(display_short)|uniprotkb:HPRT(gene name synonym)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549240|imex:IM-24995-2881	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000185.1|ensembl:ENSG00000165704(gene)|ensembl:ENST00000298556(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001913"(T cell mediated cytotoxicity)|go:"GO:0001975"(response to amphetamine)|go:"GO:0004422"(hypoxanthine phosphoribosyltransferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006164"(purine nucleotide biosynthetic process)|go:"GO:0006166"(purine ribonucleoside salvage)|go:"GO:0006168"(adenine salvage)|go:"GO:0006178"(guanine salvage)|go:"GO:0007625"(grooming behavior)|go:"GO:0007626"(locomotory behavior)|go:"GO:0021756"(striatum development)|go:"GO:0021895"(cerebral cortex neuron differentiation)|go:"GO:0021954"(central nervous system neuron development)|go:"GO:0032263"(GMP salvage)|go:"GO:0032264"(IMP salvage)|go:"GO:0042417"(dopamine metabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043103"(hypoxanthine salvage)|go:"GO:0045964"(positive regulation of dopamine metabolic process)|go:"GO:0046038"(GMP catabolic process)|go:"GO:0046040"(IMP metabolic process)|go:"GO:0046100"(hypoxanthine metabolic process)|go:"GO:0046651"(lymphocyte proliferation)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0052657"(guanine phosphoribosyltransferase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000836(Phosphoribosyltransferase)|interpro:IPR005904(Hypoxanthine phosphoribosyl transferase)|interpro:IPR029057|mint:P00492|rcsb pdb:1BZY|rcsb pdb:1D6N|rcsb pdb:1HMP|rcsb pdb:1Z7G|go:"GO:0048813"(dendrite morphogenesis)|rcsb pdb:2VFA|rcsb pdb:3GEP|rcsb pdb:3GGC|rcsb pdb:3GGJ|rcsb pdb:4IJQ|rcsb pdb:4KN6|rcsb pdb:4RAB|rcsb pdb:4RAC|rcsb pdb:4RAD|rcsb pdb:4RAN|rcsb pdb:4RAO|rcsb pdb:4RAQ|rcsb pdb:5BRN|rcsb pdb:5BSK|rcsb pdb:5HIA|rcsb pdb:5W8V|rcsb pdb:6BNJ|reactome:R-HSA-74217	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731	-	-	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:w87Sv/qOAkHFqJm0vu0Ayqlz7TA9606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:78632B161565D2D9|rigid:PISP8RuaU+d5E5vA27VfIBZftkI	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P32502	uniprotkb:P14373	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	intact:EBI-719493|uniprotkb:A2BE15|uniprotkb:Q5RJA8|uniprotkb:Q5ST26|uniprotkb:Q6LA73|uniprotkb:Q6NXR9|uniprotkb:Q9BZY6|uniprotkb:Q9UJL3|ensembl:ENSP00000383555|ensembl:ENSP00000392787|ensembl:ENSP00000405229|ensembl:ENSP00000414793|ensembl:ENSP00000366404	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:tri27_human(display_long)|uniprotkb:TRIM27(gene name)|psi-mi:TRIM27(display_short)|uniprotkb:RNF76(gene name synonym)|uniprotkb:RFP(gene name synonym)|uniprotkb:Ret finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 27(gene name synonym)|uniprotkb:RING finger protein 76(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM27(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549232|imex:IM-24995-2879	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731	refseq:NP_006501.1|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0090281"(negative regulation of calcium ion import)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR020457|interpro:IPR035791|interpro:IPR043136|mint:P14373|reactome:R-HSA-3232142|reactome:R-HSA-9635465|reactome:R-HSA-8948751|ensembl:ENSG00000204713(gene)|ensembl:ENSG00000215641(gene)|ensembl:ENSG00000229006(gene)|ensembl:ENSG00000234495(gene)|ensembl:ENSG00000237071(gene)|ensembl:ENST00000377199(transcript)|ensembl:ENST00000400720(transcript)|ensembl:ENST00000431123(transcript)|ensembl:ENST00000435528(transcript)|ensembl:ENST00000437160(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001650"(fibrillar center)|go:"GO:0002820"(negative regulation of adaptive immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)	-	crc64:A5409FAF1594854C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	rogid:dsfH5OUghD8KSaTz1SFw9OYVTK49606	intact-crc:957CE00426D7D191|rigid:8TmBF4FZuoTGdTF2GdyM2n5jne4	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P32502	intact:EBI-11525577	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	-	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:pde4dip(display_short)|psi-mi:EBI-11525577(display_long)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549236|imex:IM-24995-2880	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731	-	-	crc64:A5409FAF1594854C	no-uniprot-update:	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	rogid:1FG5rtwoLqpyiNu81cqSpFdaXDY9606	intact-crc:E9BA54346AB5AFB0|rigid:3PkRr2VqTLqLOCdfIfBqDQ8Hk2E	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P32502	uniprotkb:P15531	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	intact:EBI-741141|ensembl:ENSP00000376892|uniprotkb:Q6FGK3|uniprotkb:Q86XQ2|uniprotkb:Q9UDJ6	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:ndka_human(display_long)|uniprotkb:Tumor metastatic process-associated protein(gene name synonym)|uniprotkb:Metastasis inhibition factor nm23(gene name synonym)|uniprotkb:Granzyme A-activated DNase(gene name synonym)|uniprotkb:NME1(gene name)|psi-mi:NME1(display_short)|uniprotkb:NDPKA(gene name synonym)|uniprotkb:NM23(gene name synonym)|uniprotkb:NM23-H1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549260|imex:IM-24995-2886	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731	refseq:NP_000260.1|refseq:NP_937818.1|ensembl:ENSG00000239672(gene)|ensembl:ENST00000393196(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0002762"(negative regulation of myeloid leukocyte differentiation)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004536"(deoxyribonuclease activity)|go:"GO:0004550"(nucleoside diphosphate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0006183"(GTP biosynthetic process)|go:"GO:0006228"(UTP biosynthetic process)|go:"GO:0006241"(CTP biosynthetic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007595"(lactation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014075"(response to amine)|go:"GO:0016020"(membrane)|go:"GO:0019215"(intermediate filament binding)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051591"(response to cAMP)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071398"(cellular response to fatty acid)|interpro:IPR001564(Nucleoside diphosphate kinase, core)|go:"GO:0019899"(enzyme binding)|interpro:IPR023005|go:"GO:0021766"(hippocampus development)|interpro:IPR034907|interpro:IPR036850|mint:P15531|go:"GO:0030154"(cell differentiation)|go:"GO:0032587"(ruffle membrane)|rcsb pdb:1JXV|rcsb pdb:1UCN|go:"GO:0033574"(response to testosterone)|go:"GO:0035690"|rcsb pdb:2HVD|rcsb pdb:2HVE|rcsb pdb:3L7U|rcsb pdb:4ENO|rcsb pdb:5UI4|reactome:R-HSA-499943|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043024"(ribosomal small subunit binding)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|dip:DIP-39164N	-	crc64:A5409FAF1594854C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	rogid:Ut4gK1Xq786CaZzvqdS1eiU5op89606	intact-crc:881841A096046F4F|rigid:ApbTyx03y8NP4HEFMg5O/XwkyP8	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O95273	uniprotkb:P32502	intact:EBI-748961|uniprotkb:A8K3Q0|uniprotkb:A8K3U2|uniprotkb:Q6ZQN9|uniprotkb:Q7Z519|uniprotkb:Q8NBS7|uniprotkb:Q8NBY2|uniprotkb:Q9NS19|uniprotkb:Q9NYH3|uniprotkb:Q9UHX9|ensembl:ENSP00000300213	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:ccdb1_human(display_long)|uniprotkb:Grap2 and cyclin-D-interacting protein(gene name synonym)|uniprotkb:Human homolog of Maid(gene name synonym)|uniprotkb:CCNDBP1(gene name)|psi-mi:CCNDBP1(display_short)|uniprotkb:DIP1(gene name synonym)|uniprotkb:GCIP(gene name synonym)|uniprotkb:HHM(gene name synonym)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549256|imex:IM-24995-2885	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_036274.3|ensembl:ENSG00000166946(gene)|ensembl:ENST00000300213(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0016604"(nuclear body)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR026907|mint:O95273|rcsb pdb:3AY5	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731	-	-	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:Vi9aoFc+Mov6P3X6KGmsTxXqxvM9606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:0CD26FA751A26CD4|rigid:aQNC2q2a67Rxblovfqfkg6WAZLM	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:A0A0C4DFM0	uniprotkb:P32502	intact:EBI-11525587|ensembl:ENSP00000216465	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:a0a0c4dfm0_human(display_long)|uniprotkb:hCG_22265(orf name)|uniprotkb:GSTZ1(gene name)|psi-mi:GSTZ1(display_short)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549244|imex:IM-24995-2882	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_665877.1|ensembl:ENSG00000100577(gene)|ensembl:ENST00000216465(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0006559"(L-phenylalanine catabolic process)|go:"GO:0006572"(tyrosine catabolic process)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0016034"(maleylacetoacetate isomerase activity)|go:"GO:0016740"(transferase activity)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR005955(Maleylacetoacetate isomerase)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR034330|interpro:IPR034333|interpro:IPR036249|interpro:IPR036282|interpro:IPR040079	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731	-	-	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:kAk3W6wTlhMKasX8CzDxF6U5/jc9606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:A17166581D4D4D70|rigid:8sFEQIVUuAUQLaGakM51sY13Xcs	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P32502	uniprotkb:Q8N5R6	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	intact:EBI-740841|intact:EBI-953781|uniprotkb:B3KQ49|uniprotkb:A8K3U4|uniprotkb:A8MPQ6|uniprotkb:A8MV61|uniprotkb:A8MVU9|uniprotkb:Q9H5Q6|uniprotkb:Q8TAX6|intact:EBI-2320546|intact:EBI-11522976	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:ccd33_human(display_long)|uniprotkb:CCDC33(gene name)|psi-mi:CCDC33(display_short)|uniprotkb:Cancer/testis antigen 61(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549248|imex:IM-24995-2883	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731	refseq:NP_079331.3|interpro:IPR000008(C2 calcium-dependent membrane targeting)|go:"GO:0005777"(peroxisome)|refseq:NP_001274110.1|refseq:NP_877592.2|mint:Q8N5R6|interpro:IPR035892|interpro:IPR039889	-	crc64:A5409FAF1594854C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2021/11/30	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	rogid:eEIn7pQyfdHWx8TeLJpYy0i/gww9606	intact-crc:FDC92A6D3DC1ECE9|rigid:5jyzF2xloZxY9H2TFqrNqEYTXQA	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P32502	uniprotkb:O96006	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	intact:EBI-740037|uniprotkb:Q96BY4|ensembl:ENSP00000370616|ensembl:ENSP00000370620|ensembl:ENSP00000370621|ensembl:ENSP00000498725	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:zbed1_human(display_long)|uniprotkb:ZBED1(gene name)|psi-mi:ZBED1(display_short)|uniprotkb:ALTE(gene name synonym)|uniprotkb:DREF(gene name synonym)|uniprotkb:KIAA0785(gene name synonym)|uniprotkb:TRAMP(gene name synonym)|uniprotkb:dREF homolog(gene name synonym)|uniprotkb:Putative Ac-like transposable element(gene name synonym)|uniprotkb:DNA replication-related element-binding factor(gene name synonym)|uniprotkb:Zinc finger BED domain-containing protein 1(gene name synonym)|uniprotkb:hDREF(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549252|imex:IM-24995-2884	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731	refseq:NP_001164606.1|refseq:NP_001164607.1|refseq:NP_004720.1|ensembl:ENSG00000214717(gene)|ensembl:ENST00000381218(transcript)|ensembl:ENST00000381222(transcript)|ensembl:ENST00000381223(transcript)|ensembl:ENST00000652001(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0031965"(nuclear membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044828"(negative regulation by host of viral genome replication)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0061665"(SUMO ligase activity)|go:"GO:1990466"(protein autosumoylation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003656(Zinc finger, BED-type predicted)|interpro:IPR008906(HAT dimerisation)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR036236|mint:O96006|rcsb pdb:2CT5|reactome:R-HSA-4551638|go:"GO:0005813"(centrosome)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016605"(PML body)	-	crc64:A5409FAF1594854C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	rogid:jl97ZV2Kz5YAmQKktWt/wk7OkRw9606	intact-crc:432755D5761F71AD|rigid:xnjMmbDtA3wd0wWMkdA+FSzpBpo	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q08379	uniprotkb:P32529	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	intact:EBI-15756|uniprotkb:D6VWN4|ensemblfungi:YJR063W	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:rpa12_yeast(display_long)|uniprotkb:RPA12(gene name)|psi-mi:RPA12(display_short)|uniprotkb:RRN4(gene name synonym)|uniprotkb:YJR063W(locus name)|uniprotkb:J1747(orf name)|uniprotkb:DNA-directed RNA polymerase I 13.7 kDa polypeptide(gene name synonym)|uniprotkb:A12(gene name synonym)|uniprotkb:A12.2(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549280|imex:IM-24995-2891	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N	refseq:NP_012597.1|sgd:S000003824|dip:DIP-236N|mint:P32529|ensemblfungi:YJR063W(gene)|ensemblfungi:YJR063W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001054"(RNA polymerase I activity)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006363"(termination of RNA polymerase I transcription)|go:"GO:0006379"(mRNA cleavage)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042790"(nucleolar large rRNA transcription by RNA polymerase I)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR001222(Zinc finger, TFIIS-type)|interpro:IPR001529(DNA-directed RNA polymerase, M/15 kDa subunit)|interpro:IPR012164(DNA-directed RNA polymerase, subunit C11/M/9)|interpro:IPR019761|interpro:IPR034004|rcsb pdb:4C2M|rcsb pdb:4C3H|rcsb pdb:4C3I|rcsb pdb:4C3J|rcsb pdb:4YM7|rcsb pdb:5G5L|rcsb pdb:5LMX|rcsb pdb:5M3F|rcsb pdb:5M3M|rcsb pdb:5M5W|rcsb pdb:5M5X|rcsb pdb:5M5Y|rcsb pdb:5M64|rcsb pdb:5N5Y|rcsb pdb:5N5Z|rcsb pdb:5N60|rcsb pdb:5N61|rcsb pdb:5OA1|rcsb pdb:5W5Y|rcsb pdb:5W64|rcsb pdb:5W65|rcsb pdb:5W66|rcsb pdb:6H67|rcsb pdb:6H68|rcsb pdb:6HKO|rcsb pdb:6HLQ|rcsb pdb:6HLR|rcsb pdb:6HLS|rcsb pdb:6RQH|rcsb pdb:6RQL|rcsb pdb:6RQT|rcsb pdb:6RRD|rcsb pdb:6RUI|rcsb pdb:6RUO|rcsb pdb:6RWE|rcsb pdb:6TPS|reactome:R-SCE-73762|reactome:R-SCE-73772	-	-	crc64:D79372070819987C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2017/05/26	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	rogid:B0Zmf643W8DtAQteaDk8PVvdqW4559292	intact-crc:FAC0AC624D73B841|rigid:iRbmEMepCZ591rpMbFdcN5GsJBU	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:A0A0R4J2E4	uniprotkb:P32502	intact:EBI-11525602|ensembl:ENSP00000324292	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:a0a0r4j2e4_human(display_long)|uniprotkb:FBF1(gene name)|psi-mi:FBF1(display_short)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549276|imex:IM-24995-2890	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000188878(gene)|ensembl:ENST00000319129(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0060271"(cilium assembly)|go:"GO:0090162"(establishment of epithelial cell polarity)|go:"GO:0097539"(ciliary transition fiber)|interpro:IPR033561	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731	-	-	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/03/16	rogid:N4h8foiP1+HSYZRE7i66zhtqKlQ9606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:D2C92425A32701D3|rigid:o1ADKMU+Hf56w0Mn/5d6v5jxhCA	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P32502	uniprotkb:P20591	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	intact:EBI-929476|uniprotkb:D3DSI8|uniprotkb:B2RDA5|uniprotkb:B3KU10|uniprotkb:C9IYV7|uniprotkb:C9J8D6|uniprotkb:C9JN19|uniprotkb:C9JN88|uniprotkb:C9JUL1|uniprotkb:C9JZS6|uniprotkb:Q86YP5|uniprotkb:Q96CI3|ensembl:ENSP00000381599|ensembl:ENSP00000381601|ensembl:ENSP00000392151|ensembl:ENSP00000402215|ensembl:ENSP00000408498|ensembl:ENSP00000410523|ensembl:ENSP00000505029|ensembl:ENSP00000505047|ensembl:ENSP00000505051|ensembl:ENSP00000505189|ensembl:ENSP00000505457|ensembl:ENSP00000505489|ensembl:ENSP00000505630|ensembl:ENSP00000505657|ensembl:ENSP00000505669|ensembl:ENSP00000505781|ensembl:ENSP00000505874|ensembl:ENSP00000506047|ensembl:ENSP00000506062|ensembl:ENSP00000506183|ensembl:ENSP00000506199|ensembl:ENSP00000506220|ensembl:ENSP00000506270|ensembl:ENSP00000506348|ensembl:ENSP00000506372|ensembl:ENSP00000506395|ensembl:ENSP00000506481|ensembl:ENSP00000506512|ensembl:ENSP00000506690|ensembl:ENSP00000506712	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:mx1_human(display_long)|uniprotkb:MX1(gene name)|psi-mi:MX1(display_short)|uniprotkb:Myxovirus resistance protein 1(gene name synonym)|uniprotkb:Interferon-regulated resistance GTP-binding protein MxA(gene name synonym)|uniprotkb:Interferon-induced protein p78(gene name synonym)|uniprotkb:Myxoma resistance protein 1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549264|imex:IM-24995-2887	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731	refseq:NP_001269849.1|refseq:NP_001138397.1|refseq:NP_001171517.1|refseq:NP_002453.2|refseq:XP_011527870.1|refseq:XP_005261037.1|refseq:XP_005261038.1|refseq:XP_005261039.1|refseq:XP_005261035.1|refseq:XP_005261036.1|refseq:XP_016883838.1|refseq:XP_016883839.1|dip:DIP-35694N|ensembl:ENSG00000157601(gene)|ensembl:ENST00000398598(transcript)|ensembl:ENST00000398600(transcript)|ensembl:ENST00000413778(transcript)|ensembl:ENST00000417963(transcript)|ensembl:ENST00000419044(transcript)|ensembl:ENST00000455164(transcript)|ensembl:ENST00000679445(transcript)|ensembl:ENST00000679464(transcript)|ensembl:ENST00000679543(transcript)|ensembl:ENST00000679626(transcript)|ensembl:ENST00000679705(transcript)|ensembl:ENST00000679911(transcript)|ensembl:ENST00000680176(transcript)|ensembl:ENST00000680182(transcript)|ensembl:ENST00000680347(transcript)|ensembl:ENST00000680364(transcript)|ensembl:ENST00000680536(transcript)|ensembl:ENST00000680629(transcript)|ensembl:ENST00000680760(transcript)|ensembl:ENST00000680776(transcript)|ensembl:ENST00000681039(transcript)|ensembl:ENST00000681191(transcript)|ensembl:ENST00000681266(transcript)|ensembl:ENST00000681415(transcript)|ensembl:ENST00000681607(transcript)|ensembl:ENST00000681671(transcript)|ensembl:ENST00000681849(transcript)|ensembl:ENST00000681857(transcript)|ensembl:ENST00000681867(transcript)|ensembl:ENST00000681896(transcript)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0003374"(dynamin family protein polymerization involved in mitochondrial fission)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0006952"(defense response)|go:"GO:0007165"(signal transduction)|go:"GO:0008017"(microtubule binding)|go:"GO:0009615"(response to virus)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016185"(synaptic vesicle budding from presynaptic endocytic zone membrane)|go:"GO:0030424"(axon)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031623"(receptor internalization)|go:"GO:0031965"(nuclear membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0034340"(response to type I interferon)|go:"GO:0042802"(identical protein binding)|go:"GO:0044327"(dendritic spine head)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0051607"(defense response to virus)|go:"GO:0061025"(membrane fusion)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:0098793"(presynapse)|go:"GO:0098844"(postsynaptic endocytic zone membrane)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:0140374"(antiviral innate immune response)|interpro:IPR000375(Dynamin central region)|interpro:IPR001401(Dynamin, GTPase region)|interpro:IPR003130(Dynamin GTPase effector)|interpro:IPR019762|interpro:IPR020850|interpro:IPR022812|interpro:IPR027417|interpro:IPR030381|mint:P20591|rcsb pdb:3LJB|rcsb pdb:3SZR|rcsb pdb:3ZYS|rcsb pdb:4P4S|rcsb pdb:4P4T|rcsb pdb:4P4U|rcsb pdb:5GTM|reactome:R-HSA-1169408|reactome:R-HSA-909733	-	crc64:A5409FAF1594854C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	rogid:9rO7Zyl6v0Kq3xw6MKbVefk1hCA9606	intact-crc:E60CFF62AA322541|rigid:zxPv0WONMV/801GzpWcMFh0tNEk	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O95197-3	uniprotkb:P32502	intact:EBI-11525735|ensembl:ENSP00000440874	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:o95197-3(display_long)|uniprotkb:RTN3(gene name)|psi-mi:RTN3(display_short)|uniprotkb:ASYIP(gene name synonym)|uniprotkb:Homolog of ASY protein(gene name synonym)|uniprotkb:NSPL2(gene name synonym)|uniprotkb:Neuroendocrine-specific protein-like 2(gene name synonym)|uniprotkb:Neuroendocrine-specific protein-like II(gene name synonym)|uniprotkb:A1(isoform synonym)|uniprotkb:B1(isoform synonym)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549268|imex:IM-24995-2888	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000133318(gene)|ensembl:ENST00000537981(transcript)|intact:EBI-740467(isoform-parent)|uniprotkb:O95197-3(isoform-parent)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731	-	-	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:+TJnANu85CM52dRZ6s+hYMlUABE9606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:4ACDE6EB7465FDF6|rigid:qZKS34xaUps9By4csjsNmwDjfLQ	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P32502	uniprotkb:O43597	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	intact:EBI-742487|uniprotkb:Q5T6Z7|ensembl:ENSP00000366306|ensembl:ENSP00000366308|uniprotkb:B2R9J9	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:spy2_human(display_long)|uniprotkb:SPRY2(gene name)|psi-mi:SPRY2(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549272|imex:IM-24995-2889	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731	refseq:NP_005833.1|rcsb pdb:5HL0|reactome:R-HSA-1295596|reactome:R-HSA-182971|rcsb pdb:5HKZ|ensembl:ENST00000377102(transcript)|ensembl:ENST00000377104(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|ensembl:ENSG00000136158(gene)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030291"(protein serine/threonine kinase inhibitor activity)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031345"(negative regulation of cell projection organization)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0032587"(ruffle membrane)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0045165"(cell fate commitment)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048513"(animal organ development)|go:"GO:0051387"(negative regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060437"(lung growth)|go:"GO:0060449"(bud elongation involved in lung branching)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:1900747"(negative regulation of vascular endothelial growth factor signaling pathway)|go:"GO:1902747"(negative regulation of lens fiber cell differentiation)|go:"GO:1990752"(microtubule end)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR007875(Sprouty)|interpro:IPR030780|mint:O43597|rcsb pdb:3BUM|rcsb pdb:3OB1|rcsb pdb:5HKY|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|refseq:NP_001305465.1|refseq:NP_001305466.1|refseq:NP_001305467.1	-	crc64:A5409FAF1594854C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	rogid:u1omauzisc6MdZlogMotUmtauSI9606	intact-crc:347D07BC6D234BBA|rigid:3mEi232CWxAHeNyuaGfgfCcKtHw	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P32601	uniprotkb:P26641	intact:EBI-6178|uniprotkb:Q12299|uniprotkb:Q3S1N1|uniprotkb:D6W427|ensemblfungi:YPR017C	intact:EBI-351467|uniprotkb:Q6PJ62|uniprotkb:Q6PK31|uniprotkb:Q96CU2|uniprotkb:Q9P196|intact:EBI-2321928|uniprotkb:B4DTG2|ensembl:ENSP00000331901	psi-mi:dss4_yeast(display_long)|uniprotkb:DSS4(gene name)|psi-mi:DSS4(display_short)|uniprotkb:LPZ16C(orf name)|uniprotkb:YP9531.11C(orf name)|uniprotkb:YPR017C(locus name)	psi-mi:ef1g_human(display_long)|uniprotkb:PRO1608(orf name)|uniprotkb:EEF1G(gene name)|psi-mi:EEF1G(display_short)|uniprotkb:EF1G(gene name synonym)|uniprotkb:eEF-1B gamma(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549296|imex:IM-24995-2895	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015342.1|sgd:S000006221|dip:DIP-1423N|ensemblfungi:YPR017C(gene)|ensemblfungi:YPR017C_mRNA(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008270"(zinc ion binding)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|interpro:IPR007515(Mss4)|interpro:IPR011057(Mss4-like)|interpro:IPR011323(Mss4/translationally controlled tumour-associated TCTP)	refseq:NP_001395.1|ensembl:ENSG00000254772(gene)|ensembl:ENST00000329251(transcript)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006414"(translational elongation)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001662(Translation elongation factor EF1B, gamma chain, conserved)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR036249|interpro:IPR036282|interpro:IPR036433|interpro:IPR040079|mint:P26641|rcsb pdb:1PBU|rcsb pdb:5DQS|rcsb pdb:5JPO|reactome:R-HSA-156842|dip:DIP-32516N	-	crc64:1D7B6D3443D93AE2	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:UKF+4mfZLTZ2s5CLkImTGcwgvUw559292	rogid:biVN96umeEdPm/wvPN4VwbSRHTs9606	intact-crc:CFB30162E836A037|rigid:EvKgM1/2L6A7SHxeu5xsDJiMmf4	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P32562	uniprotkb:P14859-6	intact:EBI-4440|ensemblfungi:YMR001C|uniprotkb:D6VZH5	intact:EBI-11526590|ensembl:ENSP00000356840	psi-mi:cdc5_yeast(display_long)|uniprotkb:CDC5(gene name)|psi-mi:CDC5(display_short)|uniprotkb:MSD2(gene name synonym)|uniprotkb:PKX2(gene name synonym)|uniprotkb:YMR001C(locus name)|uniprotkb:YM8270.03C(orf name)	psi-mi:p14859-6(display_long)|uniprotkb:NF-A1(gene name synonym)|uniprotkb:OCT1(gene name synonym)|uniprotkb:OTF1(gene name synonym)|uniprotkb:Octamer-binding protein 1(gene name synonym)|uniprotkb:Octamer-binding transcription factor 1(gene name synonym)|uniprotkb:POU2F1(gene name)|psi-mi:POU2F1(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549284|imex:IM-24995-2892	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YMR001C(gene)|ensemblfungi:YMR001C_mRNA(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0000922"(spindle pole)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0010458"(exit from mitosis)|go:"GO:0010696"(positive regulation of mitotic spindle pole body separation)|go:"GO:0019237"(centromeric DNA binding)|refseq:NP_013714.1|sgd:S000004603|reactome:R-SCE-6804115|reactome:R-SCE-156711|reactome:R-SCE-162658|reactome:R-SCE-2565942|dip:DIP-2321N|reactome:R-SCE-2500257|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0035025"(positive regulation of Rho protein signal transduction)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051301"(cell division)|go:"GO:0070194"(synaptonemal complex disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0110083"(positive regulation of protein localization to cell division site involved in mitotic actomyosin contractile ring assembly)|go:"GO:1902542"(regulation of protein localization to mitotic spindle pole body)|go:"GO:1903353"(regulation of nucleus organization)|go:"GO:1904750"(negative regulation of protein localization to nucleolus)|go:"GO:1905339"(positive regulation of cohesin unloading)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033695|interpro:IPR033701|interpro:IPR036947|rcsb pdb:6MF4|rcsb pdb:6MF5|rcsb pdb:6MF6	ensembl:ENSG00000143190(gene)|ensembl:ENST00000367866(transcript)|intact:EBI-624770(isoform-parent)|uniprotkb:P14859-6(isoform-parent)	-	crc64:B5A25F1BBBEAA3DC	isoform-comment:No experimental confirmation available.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:XXSkltYvBA9Zkh0Kr5s1znazUC0559292	rogid:jKwhpG5wRMncTZjM6bNUCL0CPqQ9606	intact-crc:A71CD3BF2DF5F1EA|rigid:pKDK+p9Bd/jFaUKhj9be5X4eW2g	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
intact:EBI-11523568	uniprotkb:P32571	-	intact:EBI-19840|uniprotkb:D6VS55|ensemblfungi:YDR069C	psi-mi:nav2(display_short)|psi-mi:EBI-11523568(display_long)	psi-mi:ubp4_yeast(display_long)|uniprotkb:DOA4(gene name)|psi-mi:DOA4(display_short)|uniprotkb:MUT4(gene name synonym)|uniprotkb:SSV7(gene name synonym)|uniprotkb:YDR069C(locus name)|uniprotkb:YD9609.23C(orf name)|uniprotkb:YD8554.02C(orf name)|uniprotkb:D4270(orf name)|uniprotkb:NPI2(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 4(gene name synonym)|uniprotkb:Deubiquitinating enzyme 4(gene name synonym)|uniprotkb:Vacuole biogenesis protein SSV7(gene name synonym)|uniprotkb:Ubiquitin thioesterase 4(gene name synonym)|uniprotkb:DOS1(gene name synonym)|uniprotkb:UBP4(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549288|imex:IM-24995-2893	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	-	sgd:S000002476|ensemblfungi:YDR069C(gene)|ensemblfungi:YDR069C_mRNA(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005739"(mitochondrion)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0010992"(ubiquitin recycling)|go:"GO:0010995"(free ubiquitin chain depolymerization)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0031902"(late endosome membrane)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0070676"(intralumenal vesicle formation)|go:"GO:1904669"(ATP export)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR001763(Rhodanese-like)|interpro:IPR018200|interpro:IPR028889|interpro:IPR036873|interpro:IPR038765|refseq:NP_010354.3|dip:DIP-5298N|mint:P32571	-	no-uniprot-update:	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:WyH5VrQlZ4x7Sr5Hd4ApJ74qrL49606	rogid:UTBSWmpygyxo1ygxp/sQ8wgqnMo559292	intact-crc:274D305B3E90E003|rigid:mFA8pUXslEx569AJcgdfELXftIE	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O94972	uniprotkb:P32571	intact:EBI-741602|uniprotkb:Q7Z3E6|uniprotkb:Q8IYF7|uniprotkb:Q8WYF7|intact:EBI-28976055|ensembl:ENSP00000262294|ensembl:ENSP00000376785|uniprotkb:A8K0V9|uniprotkb:A8K8U4|uniprotkb:A8MZ79|uniprotkb:B4DGZ3|uniprotkb:F8WEE6	intact:EBI-19840|uniprotkb:D6VS55|ensemblfungi:YDR069C	psi-mi:tri37_human(display_long)|uniprotkb:Mulibrey nanism protein(gene name synonym)|uniprotkb:TRIM37(gene name)|psi-mi:TRIM37(display_short)|uniprotkb:KIAA0898(gene name synonym)|uniprotkb:MUL(gene name synonym)|uniprotkb:POB1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 37(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM37(gene name synonym)	psi-mi:ubp4_yeast(display_long)|uniprotkb:DOA4(gene name)|psi-mi:DOA4(display_short)|uniprotkb:MUT4(gene name synonym)|uniprotkb:SSV7(gene name synonym)|uniprotkb:YDR069C(locus name)|uniprotkb:YD9609.23C(orf name)|uniprotkb:YD8554.02C(orf name)|uniprotkb:D4270(orf name)|uniprotkb:NPI2(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 4(gene name synonym)|uniprotkb:Deubiquitinating enzyme 4(gene name synonym)|uniprotkb:Vacuole biogenesis protein SSV7(gene name synonym)|uniprotkb:Ubiquitin thioesterase 4(gene name synonym)|uniprotkb:DOS1(gene name synonym)|uniprotkb:UBP4(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549292|imex:IM-24995-2894	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001005207.1|refseq:NP_056109.1|refseq:NP_001307916.1|ensembl:ENSP00000262294|ensembl:ENST00000393065|ensembl:ENSP00000376784|ensembl:ENSP00000376785|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046600"(negative regulation of centriole replication)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070842"(aggresome assembly)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002083(MATH)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR008974(TRAF-like)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR037299|rcsb pdb:3LRQ|reactome:R-HSA-983168|ensembl:ENSG00000108395(gene)|ensembl:ENST00000262294(transcript)|ensembl:ENST00000393066(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005777"(peroxisome)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016235"(aggresome)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0035518"(histone H2A monoubiquitination)|refseq:NP_001307919.1|dip:DIP-34437N	sgd:S000002476|ensemblfungi:YDR069C(gene)|ensemblfungi:YDR069C_mRNA(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005739"(mitochondrion)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0010992"(ubiquitin recycling)|go:"GO:0010995"(free ubiquitin chain depolymerization)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0031902"(late endosome membrane)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0070676"(intralumenal vesicle formation)|go:"GO:1904669"(ATP export)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR001763(Rhodanese-like)|interpro:IPR018200|interpro:IPR028889|interpro:IPR036873|interpro:IPR038765|refseq:NP_010354.3|dip:DIP-5298N|mint:P32571	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:y2njeO0MUBrKU9MUvkbo1uZmqkE9606	rogid:UTBSWmpygyxo1ygxp/sQ8wgqnMo559292	intact-crc:09199396109C1A8B|rigid:Fip2dzLdN2rSbGgYxEH7/vyk+oU	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8N5R6	uniprotkb:P32844	intact:EBI-740841|intact:EBI-953781|uniprotkb:B3KQ49|uniprotkb:A8K3U4|uniprotkb:A8MPQ6|uniprotkb:A8MV61|uniprotkb:A8MVU9|uniprotkb:Q9H5Q6|uniprotkb:Q8TAX6|intact:EBI-2320546|intact:EBI-11522976	intact:EBI-16874|uniprotkb:D6VVL6|ensemblfungi:YIL068C	psi-mi:ccd33_human(display_long)|uniprotkb:CCDC33(gene name)|psi-mi:CCDC33(display_short)|uniprotkb:Cancer/testis antigen 61(gene name synonym)	psi-mi:sec6_yeast(display_long)|uniprotkb:YIL068C(locus name)|uniprotkb:SEC6(gene name)|psi-mi:SEC6(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549316|imex:IM-24995-2900	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_079331.3|interpro:IPR000008(C2 calcium-dependent membrane targeting)|go:"GO:0005777"(peroxisome)|refseq:NP_001274110.1|refseq:NP_877592.2|mint:Q8N5R6|interpro:IPR035892|interpro:IPR039889	refseq:NP_012196.1|sgd:S000001330|ensemblfungi:YIL068C(gene)|ensemblfungi:YIL068C_mRNA(transcript)|go:"GO:0000145"(exocyst)|go:"GO:0000149"(SNARE binding)|go:"GO:0005628"(prospore membrane)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0015031"(protein transport)|go:"GO:0035544"(negative regulation of SNARE complex assembly)|go:"GO:0043332"(mating projection tip)|go:"GO:0051601"(exocyst localization)|go:"GO:0090522"(vesicle tethering involved in exocytosis)|interpro:IPR010326(Exocyst complex component Sec6)|interpro:IPR042532|rcsb pdb:2FJI|rcsb pdb:5YFP|rcsb pdb:6VKL|reactome:R-SCE-264876|dip:DIP-5649N|mint:P32844	-	-	crc64:2B09BBBE15389239	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2021/11/30	rogid:eEIn7pQyfdHWx8TeLJpYy0i/gww9606	rogid:SJtUIHyBTy38oPOc0h4D3Anipvc559292	intact-crc:99126B4EF8AD5C7B|rigid:x4nnJ1Ba4hXL5Wbd4a9rc+M/1as	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q08379	uniprotkb:P32831	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	intact:EBI-12002|ensemblfungi:YBR212W|uniprotkb:D6VQK8	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:ngr1_yeast(display_long)|uniprotkb:NGR1(gene name)|psi-mi:NGR1(display_short)|uniprotkb:RBP1(gene name synonym)|uniprotkb:YBR212W(locus name)|uniprotkb:YBR1459(orf name)|uniprotkb:RNA-binding protein RBP1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549312|imex:IM-24995-2899	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N	ensemblfungi:YBR212W(gene)|ensemblfungi:YBR212W_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|refseq:NP_009771.3|sgd:S000000416|mint:P32831|dip:DIP-5160N	-	-	crc64:12F64EC4C5716750	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2017/05/26	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	rogid:MCNbYrmWkUp7dAyKpebSKsIzOxA559292	intact-crc:F6A800410F50E6C4|rigid:v3TpDbdeJVmyOr+hoErXJ5VXAF0	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P32610	uniprotkb:P19012	intact:EBI-20264|uniprotkb:D3DLJ9|ensemblfungi:YEL051W	intact:EBI-739566|uniprotkb:Q53XV8|uniprotkb:Q9BUG4|uniprotkb:B3KQY1|uniprotkb:B3KRA2|uniprotkb:E0CX14|ensembl:ENSP00000254043|ensembl:ENSP00000377546	psi-mi:vatd_yeast(display_long)|uniprotkb:VMA8(gene name)|psi-mi:VMA8(display_short)|uniprotkb:YEL051W(locus name)|uniprotkb:SYGP-ORF11(orf name)|uniprotkb:Vacuolar proton pump subunit D(gene name synonym)	psi-mi:k1c15_human(display_long)|uniprotkb:KRT15(gene name)|psi-mi:KRT15(display_short)|uniprotkb:KRTB(gene name synonym)|uniprotkb:Cytokeratin-15(gene name synonym)|uniprotkb:Keratin-15(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549300|imex:IM-24995-2896	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010863.1|sgd:S000000777|ensemblfungi:YEL051W(gene)|ensemblfungi:YEL051W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0016471"(vacuolar proton-transporting V-type ATPase complex)|go:"GO:0033176"(proton-transporting V-type ATPase complex)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR002699(ATPase, V1/A1 complex, subunit D)|rcsb pdb:3J9T|rcsb pdb:3J9U|rcsb pdb:3J9V|rcsb pdb:4RND|rcsb pdb:5BW9|rcsb pdb:5D80|rcsb pdb:5VOX|rcsb pdb:5VOY|rcsb pdb:5VOZ|rcsb pdb:6O7V|rcsb pdb:6O7W|rcsb pdb:6O7X|reactome:R-SCE-1222556|reactome:R-SCE-6798695|reactome:R-SCE-77387|reactome:R-SCE-917977|reactome:R-SCE-9639288|dip:DIP-2959N|mint:P32610	refseq:NP_002266.2|ensembl:ENSG00000171346(gene)|ensembl:ENST00000254043(transcript)|ensembl:ENST00000393976(transcript)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0008544"(epidermis development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097110"(scaffold protein binding)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR039008|mint:P19012|reactome:R-HSA-6805567|reactome:R-HSA-6809371	-	crc64:FDE93E1FAF0AEC5B	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:rrwRno7lCnDeTNwawONkGwV8Hkg559292	rogid:WrZQBYQvrWcfrR5ojWXrXp6spPE9606	intact-crc:E47AFD1AD3D3B49E|rigid:xGHgIT8Lu5s5UtthxS5AsbS9L9E	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P32622	uniprotkb:O95544	intact:EBI-22350|uniprotkb:D3DLK8|ensemblfungi:YEL041W	intact:EBI-743949|uniprotkb:Q9H931|uniprotkb:A8K296|uniprotkb:A6NNN3|uniprotkb:B7Z434|uniprotkb:F5GXR5|uniprotkb:Q5QPS4|uniprotkb:Q9H2P2|ensembl:ENSP00000341679|ensembl:ENSP00000344340	psi-mi:yef1_yeast(display_long)|uniprotkb:YEF1(gene name)|psi-mi:YEF1(display_short)|uniprotkb:SYGP-ORF17(orf name)|uniprotkb:YEL041W(locus name)	psi-mi:nadk_human(display_long)|uniprotkb:"Poly(P)/ATP NAD kinase"(gene name synonym)|uniprotkb:NADK(gene name)|psi-mi:NADK(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549304|imex:IM-24995-2897	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010873.1|sgd:S000000767|dip:DIP-1885N|mint:P32622|ensemblfungi:YEL041W(gene)|ensemblfungi:YEL041W_mRNA(transcript)|go:"GO:0003951"(NAD+ kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006741"(NADP biosynthetic process)|go:"GO:0019674"(NAD metabolic process)|go:"GO:0042736"(NADH kinase activity)|interpro:IPR002504(ATP-NAD/AcoX kinase)|interpro:IPR016064(ATP-NAD kinase, PpnK-type)|interpro:IPR017437(ATP-NAD kinase, PpnK-type, all-beta)|interpro:IPR017438(ATP-NAD kinase, PpnK-type, alpha/beta)	refseq:NP_001185922.1|refseq:NP_001185923.1|refseq:NP_001185924.1|refseq:NP_075394.3|refseq:XP_005244835.1|refseq:XP_006710900.1|ensembl:ENSG00000008130(gene)|ensembl:ENST00000341426(transcript)|ensembl:ENST00000341991(transcript)|go:"GO:0003951"(NAD+ kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006741"(NADP biosynthetic process)|go:"GO:0016310"(phosphorylation)|go:"GO:0019674"(NAD metabolic process)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046872"(metal ion binding)|interpro:IPR002504(ATP-NAD/AcoX kinase)|interpro:IPR016064(ATP-NAD kinase, PpnK-type)|interpro:IPR017437(ATP-NAD kinase, PpnK-type, all-beta)|interpro:IPR017438(ATP-NAD kinase, PpnK-type, alpha/beta)|mint:O95544|rcsb pdb:3PFN|reactome:R-HSA-196807	-	crc64:E8301D466249DA27	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:HAL9emGKdVRCmdDG9CMzn68CGUI559292	rogid:XPfRviZiKsV+1JOUi7BsMrIa3M49606	intact-crc:D10B1895AEBF5E0E|rigid:/mJyZP7jnOwR5pOfg2RO3cVZgVU	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P32622	uniprotkb:P19474	intact:EBI-22350|uniprotkb:D3DLK8|ensemblfungi:YEL041W	intact:EBI-81290|uniprotkb:Q96RF8|uniprotkb:Q5XPV5|ensembl:ENSP00000254436	psi-mi:yef1_yeast(display_long)|uniprotkb:YEF1(gene name)|psi-mi:YEF1(display_short)|uniprotkb:SYGP-ORF17(orf name)|uniprotkb:YEL041W(locus name)	psi-mi:ro52_human(display_long)|uniprotkb:TRIM21(gene name)|psi-mi:TRIM21(display_short)|uniprotkb:RNF81(gene name synonym)|uniprotkb:Sjoegren syndrome type A antigen(gene name synonym)|uniprotkb:"Ro(SS-A)"(gene name synonym)|uniprotkb:52 kDa ribonucleoprotein autoantigen Ro/SS-A(gene name synonym)|uniprotkb:Tripartite motif-containing protein 21(gene name synonym)|uniprotkb:RING finger protein 81(gene name synonym)|uniprotkb:52 kDa Ro protein(gene name synonym)|uniprotkb:RO52(gene name synonym)|uniprotkb:SSA1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM21(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549308|imex:IM-24995-2898	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010873.1|sgd:S000000767|dip:DIP-1885N|mint:P32622|ensemblfungi:YEL041W(gene)|ensemblfungi:YEL041W_mRNA(transcript)|go:"GO:0003951"(NAD+ kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006741"(NADP biosynthetic process)|go:"GO:0019674"(NAD metabolic process)|go:"GO:0042736"(NADH kinase activity)|interpro:IPR002504(ATP-NAD/AcoX kinase)|interpro:IPR016064(ATP-NAD kinase, PpnK-type)|interpro:IPR017437(ATP-NAD kinase, PpnK-type, all-beta)|interpro:IPR017438(ATP-NAD kinase, PpnK-type, alpha/beta)	refseq:NP_003132.2|go:"GO:0019901"(protein kinase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031648"(protein destabilization)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032479"(regulation of type I interferon production)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045824"(negative regulation of innate immune response)|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046598"(positive regulation of viral entry into host cell)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0090086"(negative regulation of protein deubiquitination)|ensembl:ENSG00000132109(gene)|ensembl:ENST00000254436(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000932"(P-body)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0007049"(cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR020457|interpro:IPR035831|interpro:IPR043136|mint:P19474|rcsb pdb:2IWG|rcsb pdb:5JPX|rcsb pdb:5OLM|rcsb pdb:6FGA|rcsb pdb:6S53|rcsb pdb:7BBD|reactome:R-HSA-1834941|reactome:R-HSA-3134975|reactome:R-HSA-877300|reactome:R-HSA-983168|go:"GO:1902187"|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003613(U box)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)	-	crc64:E8301D466249DA27	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:HAL9emGKdVRCmdDG9CMzn68CGUI559292	rogid:/9rpwdudXQWv8z8JLmRecXf3YQM9606	intact-crc:6E1A5D26837E7D7C|rigid:gt8pj4ZDFSCdBUapixL/5NGgO+s	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q7Z6G3-2	uniprotkb:P32902	intact:EBI-10172876|ensembl:ENSP00000457354|intact:EBI-14062040	intact:EBI-16248|ensemblfungi:YHL004W|uniprotkb:D3DKR0	psi-mi:q7z6g3-2(display_long)|uniprotkb:EFCBP2(gene name synonym)|uniprotkb:Neuronal calcium-binding protein 2(gene name synonym)|uniprotkb:Synaptotagmin-interacting protein 2(gene name synonym)|uniprotkb:NECAB2(gene name)|psi-mi:NECAB2(display_short)	psi-mi:rt04_yeast(display_long)|uniprotkb:MRP4(gene name)|psi-mi:MRP4(display_short)|uniprotkb:MRP4A(gene name synonym)|uniprotkb:Mitochondrial small ribosomal subunit protein uS2m(gene name synonym)|uniprotkb:YHL004W(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549328|imex:IM-24995-2903	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000103154(gene)|ensembl:ENST00000565691(transcript)|uniprotkb:Q7Z6G3-2(isoform-parent)|intact:EBI-950070(isoform-parent)	ensemblfungi:YHL004W(gene)|ensemblfungi:YHL004W_mRNA(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR001865(Ribosomal protein S2)|interpro:IPR005706(Ribosomal protein S2, bacterial-type)|interpro:IPR018130|interpro:IPR023591|rcsb pdb:5MRC|rcsb pdb:5MRE|rcsb pdb:5MRF|refseq:NP_011859.1|sgd:S000000996|dip:DIP-5035N|mint:P32902	-	-	crc64:81A1CB33134BC559	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:4S7oIx6h+mKzV3EPxqcfMNqaNko9606	rogid:BlL3W6HUN+uAKF/AxwlV1zT5YZQ559292	intact-crc:365D491556A37EF2|rigid:m58Zj9qZ8WkdvEdqLw8LDRMDctM	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P32902	uniprotkb:O95273	intact:EBI-16248|ensemblfungi:YHL004W|uniprotkb:D3DKR0	intact:EBI-748961|uniprotkb:A8K3Q0|uniprotkb:A8K3U2|uniprotkb:Q6ZQN9|uniprotkb:Q7Z519|uniprotkb:Q8NBS7|uniprotkb:Q8NBY2|uniprotkb:Q9NS19|uniprotkb:Q9NYH3|uniprotkb:Q9UHX9|ensembl:ENSP00000300213	psi-mi:rt04_yeast(display_long)|uniprotkb:MRP4(gene name)|psi-mi:MRP4(display_short)|uniprotkb:MRP4A(gene name synonym)|uniprotkb:Mitochondrial small ribosomal subunit protein uS2m(gene name synonym)|uniprotkb:YHL004W(locus name)	psi-mi:ccdb1_human(display_long)|uniprotkb:Grap2 and cyclin-D-interacting protein(gene name synonym)|uniprotkb:Human homolog of Maid(gene name synonym)|uniprotkb:CCNDBP1(gene name)|psi-mi:CCNDBP1(display_short)|uniprotkb:DIP1(gene name synonym)|uniprotkb:GCIP(gene name synonym)|uniprotkb:HHM(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549320|imex:IM-24995-2901	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YHL004W(gene)|ensemblfungi:YHL004W_mRNA(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR001865(Ribosomal protein S2)|interpro:IPR005706(Ribosomal protein S2, bacterial-type)|interpro:IPR018130|interpro:IPR023591|rcsb pdb:5MRC|rcsb pdb:5MRE|rcsb pdb:5MRF|refseq:NP_011859.1|sgd:S000000996|dip:DIP-5035N|mint:P32902	refseq:NP_036274.3|ensembl:ENSG00000166946(gene)|ensembl:ENST00000300213(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0016604"(nuclear body)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR026907|mint:O95273|rcsb pdb:3AY5	-	crc64:81A1CB33134BC559	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:BlL3W6HUN+uAKF/AxwlV1zT5YZQ559292	rogid:Vi9aoFc+Mov6P3X6KGmsTxXqxvM9606	intact-crc:55D13E779A68704C|rigid:BDD/Zudt6reIXIk4+QnpoexF8Bc	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P13196	uniprotkb:P32902	intact:EBI-3905054|ensembl:ENSP00000309259|ensembl:ENSP00000378416|ensembl:ENSP00000417719|ensembl:ENSP00000418779	intact:EBI-16248|ensemblfungi:YHL004W|uniprotkb:D3DKR0	psi-mi:hem1_human(display_long)|uniprotkb:ALAS1(gene name)|psi-mi:ALAS1(display_short)|uniprotkb:ALAS3(gene name synonym)|uniprotkb:ALASH(gene name synonym)|uniprotkb:5-aminolevulinic acid synthase 1(gene name synonym)|uniprotkb:Delta-ALA synthase 1(gene name synonym)|uniprotkb:Delta-aminolevulinate synthase 1(gene name synonym)|uniprotkb:OK/SW-cl.121(orf name)	psi-mi:rt04_yeast(display_long)|uniprotkb:MRP4(gene name)|psi-mi:MRP4(display_short)|uniprotkb:MRP4A(gene name synonym)|uniprotkb:Mitochondrial small ribosomal subunit protein uS2m(gene name synonym)|uniprotkb:YHL004W(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549324|imex:IM-24995-2902	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001291372.1|refseq:NP_001291373.1|refseq:NP_000679.1|refseq:NP_954635.1|go:"GO:0006783"(heme biosynthetic process)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0042541"(hemoglobin biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0048821"(erythrocyte development)|ensembl:ENSG00000023330(gene)|ensembl:ENST00000310271(transcript)|ensembl:ENST00000394965(transcript)|ensembl:ENST00000469224(transcript)|ensembl:ENST00000484952(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0003870"(5-aminolevulinate synthase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|interpro:IPR001917(Aminotransferase, class-II, pyridoxal-phosphate binding site)|interpro:IPR004839(Aminotransferase, class I and II)|interpro:IPR010961(Tetrapyrrole biosynthesis, 5-aminolevulinic acid synthase)|interpro:IPR015118(5-aminolevulinate synthase presequence)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|mint:P13196|reactome:R-HSA-189451|reactome:R-HSA-1989781|reactome:R-HSA-2151201|go:"GO:0006782"(protoporphyrinogen IX biosynthetic process)	ensemblfungi:YHL004W(gene)|ensemblfungi:YHL004W_mRNA(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR001865(Ribosomal protein S2)|interpro:IPR005706(Ribosomal protein S2, bacterial-type)|interpro:IPR018130|interpro:IPR023591|rcsb pdb:5MRC|rcsb pdb:5MRE|rcsb pdb:5MRF|refseq:NP_011859.1|sgd:S000000996|dip:DIP-5035N|mint:P32902	-	-	crc64:81A1CB33134BC559	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:HFjJ6zrRF9UYD7LMB6A3CcxcS7c9606	rogid:BlL3W6HUN+uAKF/AxwlV1zT5YZQ559292	intact-crc:A48D98EA52347B11|rigid:hNk4Ti++B/6J9ajZ8u5eL5h10cY	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P33417	uniprotkb:B0QYN7	intact:EBI-9401|ensemblfungi:YKL032C|uniprotkb:D6VXQ4	intact:EBI-11525376|ensembl:ENSP00000384361	psi-mi:ixr1_yeast(display_long)|uniprotkb:IXR1(gene name)|psi-mi:IXR1(display_short)|uniprotkb:ORD1(gene name synonym)|uniprotkb:YKL032C(locus name)|uniprotkb:YKL245(orf name)|uniprotkb:Structure-specific recognition protein(gene name synonym)	psi-mi:b0qyn7_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549344|imex:IM-24995-2907	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YKL032C(gene)|ensemblfungi:YKL032C_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0072718"(response to cisplatin)|go:"GO:0090069"(regulation of ribosome biogenesis)|go:"GO:2000819"(regulation of nucleotide-excision repair)|go:"GO:0005634"(nucleus)|reactome:R-SCE-5620971|reactome:R-SCE-5686938|reactome:R-SCE-6798695|sgd:S000001515|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR036910|refseq:NP_012893.3|interpro:IPR033311|reactome:R-SCE-140342	refseq:XP_005255597.1|refseq:XP_005255598.1|refseq:XP_011520946.1|refseq:XP_011520947.1|ensembl:ENSG00000103275(gene)|ensembl:ENST00000402301(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0016740"(transferase activity)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:owYbshNfmIe1+4PkRItBvAQ2GN0559292	rogid:zMqQOA+nnCUquTIxAUwemkElTYI9606	intact-crc:C7798F7DBAA816DC|rigid:5YXDqeqEV5DFKDVx4WmvJ0fP0ik	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P32902	intact:EBI-11525577	intact:EBI-16248|ensemblfungi:YHL004W|uniprotkb:D3DKR0	-	psi-mi:rt04_yeast(display_long)|uniprotkb:MRP4(gene name)|psi-mi:MRP4(display_short)|uniprotkb:MRP4A(gene name synonym)|uniprotkb:Mitochondrial small ribosomal subunit protein uS2m(gene name synonym)|uniprotkb:YHL004W(locus name)	psi-mi:pde4dip(display_short)|psi-mi:EBI-11525577(display_long)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549332|imex:IM-24995-2904	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YHL004W(gene)|ensemblfungi:YHL004W_mRNA(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR001865(Ribosomal protein S2)|interpro:IPR005706(Ribosomal protein S2, bacterial-type)|interpro:IPR018130|interpro:IPR023591|rcsb pdb:5MRC|rcsb pdb:5MRE|rcsb pdb:5MRF|refseq:NP_011859.1|sgd:S000000996|dip:DIP-5035N|mint:P32902	-	-	crc64:81A1CB33134BC559	no-uniprot-update:	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:BlL3W6HUN+uAKF/AxwlV1zT5YZQ559292	rogid:1FG5rtwoLqpyiNu81cqSpFdaXDY9606	intact-crc:5474FF364865DF56|rigid:RLNKJwoWVyDqVcuX5iOyxTOx78U	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O95751	uniprotkb:P32902	intact:EBI-740738|ensembl:ENSP00000359557|uniprotkb:Q6IAR6	intact:EBI-16248|ensemblfungi:YHL004W|uniprotkb:D3DKR0	psi-mi:ldoc1_human(display_long)|uniprotkb:Leucine zipper protein down-regulated in cancer cells(gene name synonym)|uniprotkb:LDOC1(gene name)|psi-mi:LDOC1(display_short)|uniprotkb:BCUR1(gene name synonym)	psi-mi:rt04_yeast(display_long)|uniprotkb:MRP4(gene name)|psi-mi:MRP4(display_short)|uniprotkb:MRP4A(gene name synonym)|uniprotkb:Mitochondrial small ribosomal subunit protein uS2m(gene name synonym)|uniprotkb:YHL004W(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549336|imex:IM-24995-2905	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_036449.1|ensembl:ENSG00000182195(gene)|ensembl:ENST00000370526(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071225"(cellular response to muramyl dipeptide)|interpro:IPR032549|interpro:IPR032567	ensemblfungi:YHL004W(gene)|ensemblfungi:YHL004W_mRNA(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR001865(Ribosomal protein S2)|interpro:IPR005706(Ribosomal protein S2, bacterial-type)|interpro:IPR018130|interpro:IPR023591|rcsb pdb:5MRC|rcsb pdb:5MRE|rcsb pdb:5MRF|refseq:NP_011859.1|sgd:S000000996|dip:DIP-5035N|mint:P32902	-	-	crc64:81A1CB33134BC559	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:Ediu0oNiZ/+YVY8l3fNdgP5A+v09606	rogid:BlL3W6HUN+uAKF/AxwlV1zT5YZQ559292	intact-crc:5AB98F733C74B1BF|rigid:3j66pJ42LxFcWILS+fD3GiJbTE4	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P33297	uniprotkb:P18848	intact:EBI-13920|uniprotkb:D6W2H6|ensemblfungi:YOR117W	intact:EBI-492498|uniprotkb:Q9UH31|ensembl:ENSP00000336790|ensembl:ENSP00000379912|ensembl:ENSP00000501783|ensembl:ENSP00000501863|ensembl:ENSP00000502400|ensembl:ENSP00000502610|ensembl:ENSP00000505360|ensembl:ENSP00000384587|intact:EBI-740263|uniprotkb:Q96AQ3	psi-mi:prs6a_yeast(display_long)|uniprotkb:RPT5(gene name)|psi-mi:RPT5(display_short)|uniprotkb:YTA1(gene name synonym)|uniprotkb:YOR117W(locus name)|uniprotkb:O3258(orf name)|uniprotkb:YOR3258W(orf name)|uniprotkb:Tat-binding protein homolog 1(gene name synonym)	psi-mi:atf4_human(display_long)|uniprotkb:Activating transcription factor 4(gene name synonym)|uniprotkb:CREB2(gene name synonym)|uniprotkb:ATF4(gene name)|psi-mi:ATF4(display_short)|uniprotkb:TXREB(gene name synonym)|uniprotkb:Cyclic AMP-responsive element-binding protein 2(gene name synonym)|uniprotkb:Tax-responsive enhancer element-binding protein 67(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549340|imex:IM-24995-2906	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005643|rcsb pdb:3WHL|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MP9|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|rcsb pdb:3WHK|reactome:R-SCE-5689880|reactome:R-SCE-6798695|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|ensemblfungi:YOR117W(gene)|ensemblfungi:YOR117W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0070682"(proteasome regulatory particle assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035254|interpro:IPR041569|rcsb pdb:3JCO|rcsb pdb:3JCP|refseq:NP_014760.3|mint:P33297|dip:DIP-1590N	refseq:NP_001666.2|refseq:NP_877962.1|ensembl:ENSG00000128272(gene)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005886"(plasma membrane)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008140"(cAMP response element binding protein binding)|go:"GO:0010575"(positive regulation of vascular endothelial growth factor production)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030282"(bone mineralization)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0032057"(negative regulation of translational initiation in response to stress)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070309"(lens fiber cell morphogenesis)|go:"GO:0070982"(L-asparagine metabolic process)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0140467"(integrated stress response signaling)|go:"GO:0140468"(HRI-mediated signaling)|go:"GO:1903204"(negative regulation of oxidative stress-induced neuron death)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:1990037"(Lewy body core)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990589"(ATF4-CREB1 transcription factor complex)|go:"GO:1990590"(ATF1-ATF4 transcription factor complex)|go:"GO:1990617"(CHOP-ATF4 complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029811|mint:P18848|rcsb pdb:1CI6|reactome:R-HSA-380994|reactome:R-HSA-381042|reactome:R-HSA-381183|reactome:R-HSA-9633012|reactome:R-HSA-9648895|go:"GO:0043005"(neuron projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045667"(regulation of osteoblast differentiation)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0036003"(positive regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0036091"(positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress)|go:"GO:0036499"(PERK-mediated unfolded protein response)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0061395"(positive regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|ensembl:ENST00000337304(transcript)|ensembl:ENST00000396680(transcript)|ensembl:ENST00000404241(transcript)|ensembl:ENST00000674568(transcript)|ensembl:ENST00000674835(transcript)|ensembl:ENST00000674920(transcript)|ensembl:ENST00000676346(transcript)|ensembl:ENST00000679776(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|refseq:XP_016884296.1|dip:DIP-354N	-	crc64:C215422033FCE830	crc64:3BBB7379DC3B0D07|comment:"No Uniprot Update and Caution  removed \" The protein could not be merged with EBI-12907955 because of some conflicts with the protein sequence (features which cannot be shifted).\" -EBI-12907955 no longer exists."	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:jsQE3SjBA0ZZcysuLgFe/5M6pOc559292	rogid:2UolKWXxKFddysaOo70/U/1pI5k9606	intact-crc:70DB77BFD75FE356|rigid:LpstdSOApZI5A94yRRNDD3wsmz0	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P35180	uniprotkb:O43765	intact:EBI-12522|uniprotkb:D6VUL4|ensemblfungi:YGR082W	intact:EBI-347996|ensembl:ENSP00000221566|ensembl:ENSP00000503397|ensembl:ENSP00000504495|uniprotkb:Q9BTZ9|intact:EBI-1045243|uniprotkb:Q6FIA9|uniprotkb:D6W610	psi-mi:tom20_yeast(display_long)|uniprotkb:MOM19(gene name synonym)|uniprotkb:YGR082W(locus name)|uniprotkb:TOM20(gene name)|psi-mi:TOM20(display_short)|uniprotkb:MAS20(gene name synonym)|uniprotkb:Mitochondrial 20 kDa outer membrane protein(gene name synonym)|uniprotkb:Translocase of outer membrane 20 kDa subunit(gene name synonym)|uniprotkb:Protein MAS20(gene name synonym)	psi-mi:sgta_human(display_long)|uniprotkb:SGTA(gene name)|psi-mi:SGTA(display_short)|uniprotkb:SGT(gene name synonym)|uniprotkb:Alpha-SGT(gene name synonym)|uniprotkb:Vpu-binding protein(gene name synonym)|uniprotkb:SGT1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549360|imex:IM-24995-2911	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YGR082W(gene)|ensemblfungi:YGR082W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005742"(mitochondrial outer membrane translocase complex)|go:"GO:0016031"(tRNA import into mitochondrion)|go:"GO:0030150"(protein import into mitochondrial matrix)|go:"GO:0030943"(mitochondrion targeting sequence binding)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|interpro:IPR002056(Protein import receptor MAS20)|interpro:IPR023392|refseq:NP_011596.1|sgd:S000003314|dip:DIP-2539N|mint:P35180	rcsb pdb:4CPG|rcsb pdb:4GOD|rcsb pdb:4GOE|rcsb pdb:4GOF|reactome:R-HSA-9609523|rcsb pdb:2VYI|ensembl:ENSG00000104969(gene)|ensembl:ENST00000221566(transcript)|ensembl:ENST00000676943(transcript)|ensembl:ENST00000677149(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072380"(TRC complex)|go:"GO:0098850"(extrinsic component of synaptic vesicle membrane)|go:"GO:1903070"(negative regulation of ER-associated ubiquitin-dependent protein catabolic process)|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)|go:"GO:1903646"(positive regulation of chaperone-mediated protein folding)|go:"GO:1904288"(BAT3 complex binding)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR032374|mint:O43765|refseq:XP_011526480.1|refseq:NP_003012.1	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:7U00YLVWcaegWlJEKzGblv6STx4559292	rogid:r/Cyj4UJk/cS8QdrbjhTZMPCigI9606	intact-crc:651C5030C71618C0|rigid:tCGv0+3PfHGj2CCWFtHvrRZkpUo	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P33750	uniprotkb:O14641	intact:EBI-17651|uniprotkb:D6VXZ1|ensemblfungi:YLL011W	intact:EBI-740850|ensembl:ENSP00000005340|uniprotkb:Q53XM0|uniprotkb:D3DTN3	psi-mi:dca13_yeast(display_long)|uniprotkb:SOF1(gene name)|psi-mi:SOF1(display_short)|uniprotkb:YLL011W(locus name)|uniprotkb:L1339(orf name)|uniprotkb:U3 small nucleolar RNA-associated protein SOF1(gene name synonym)	psi-mi:dvl2_human(display_long)|uniprotkb:DSH homolog 2(gene name synonym)|uniprotkb:DVL2(gene name)|psi-mi:DVL2(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549348|imex:IM-24995-2908	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YLL011W(gene)|ensemblfungi:YLL011W_mRNA(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003729"(mRNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0030686"(90S preribosome)|go:"GO:0032040"(small-subunit processome)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR007287(Sof1-like protein)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR020472|interpro:IPR036322|rcsb pdb:5WLC|rcsb pdb:6KE6|rcsb pdb:6LQP|rcsb pdb:6LQQ|rcsb pdb:6LQR|rcsb pdb:6LQS|rcsb pdb:6LQT|rcsb pdb:6LQU|rcsb pdb:6LQV|rcsb pdb:6ND4|rcsb pdb:6ZQA|rcsb pdb:6ZQB|rcsb pdb:6ZQC|rcsb pdb:6ZQD|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-6791226|refseq:NP_013090.1|sgd:S000003934|dip:DIP-746N|mint:P33750	refseq:NP_004413.1|ensembl:ENSG00000004975(gene)|ensembl:ENST00000005340(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005109"(frizzled binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0007507"(heart development)|go:"GO:0016235"(aggresome)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044340"(canonical Wnt signaling pathway involved in regulation of cell proliferation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0150012"(positive regulation of neuron projection arborization)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008341(Dishevelled-2 region)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:O14641|rcsb pdb:2REY|rcsb pdb:3CBX|rcsb pdb:3CBY|rcsb pdb:3CBZ|rcsb pdb:3CC0|rcsb pdb:4WIP|rcsb pdb:5LNP|rcsb pdb:5SUY|rcsb pdb:5SUZ|rcsb pdb:6IW3|rcsb pdb:6JCK|reactome:R-HSA-201681|reactome:R-HSA-201688|reactome:R-HSA-2028269|reactome:R-HSA-4086400|reactome:R-HSA-4608870|reactome:R-HSA-4641258|reactome:R-HSA-4641262|reactome:R-HSA-5099900|reactome:R-HSA-5368598|reactome:R-HSA-5663220|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9673324|ensembl:ENSP00000005340|dip:DIP-34433N	-	crc64:4B28371CC61DE7E4	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:stTLdABNsa3SvTkNOZBteSNAVJA559292	rogid:2Vdc8oRnT4Mz/j+EXQXrL3AszOc9606	intact-crc:7B09FC6BA4F9A8D0|rigid:j4xjxtpoVQnl/tte5rWikoJ91So	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P35176	uniprotkb:O43681	intact:EBI-5458|uniprotkb:D6VST3|ensemblfungi:YDR304C	intact:EBI-2515857|ensembl:ENSP00000349887|ensembl:ENSP00000466379|uniprotkb:Q53FC6|uniprotkb:A8K740|uniprotkb:A6NHP8|uniprotkb:Q92849|intact:EBI-2818109	psi-mi:cypd_yeast(display_long)|uniprotkb:CPR5(gene name)|psi-mi:CPR5(display_short)|uniprotkb:YDR304C(locus name)|uniprotkb:D9740.14(orf name)|uniprotkb:CYP5(gene name synonym)|uniprotkb:CYPD(gene name synonym)|uniprotkb:Cyclophilin D(gene name synonym)|uniprotkb:Rotamase D(gene name synonym)	psi-mi:get3_human(display_long)|uniprotkb:GET3(gene name)|psi-mi:GET3(display_short)|uniprotkb:ARSA(gene name synonym)|uniprotkb:ASNA1(gene name synonym)|uniprotkb:Arsenical pump-driving ATPase(gene name synonym)|uniprotkb:Arsenite-stimulated ATPase(gene name synonym)|uniprotkb:Guided entry of tail-anchored proteins factor 3, ATPase(gene name synonym)|uniprotkb:TRC40(gene name synonym)|uniprotkb:Transmembrane domain recognition complex 40 kDa ATPase subunit(gene name synonym)|uniprotkb:hARSA-I(gene name synonym)|uniprotkb:hASNA-I(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549352|imex:IM-24995-2909	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002712|refseq:NP_010590.3|dip:DIP-5222N|mint:P35176|ensemblfungi:YDR304C(gene)|ensemblfungi:YDR304C_mRNA(transcript)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006457"(protein folding)|go:"GO:0016018"(cyclosporin A binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|interpro:IPR020892|interpro:IPR029000	ensembl:ENSG00000198356(gene)|ensembl:ENST00000357332(transcript)|ensembl:ENST00000591090(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0015105"(arsenite transmembrane transporter activity)|go:"GO:0016787"(hydrolase activity)|go:"GO:0043529"(GET complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|interpro:IPR016300(Arsenite-transporting ATPase)|interpro:IPR025723|interpro:IPR027417|interpro:IPR027542|mint:O43681|rcsb pdb:6SO5|reactome:R-HSA-9609523|refseq:NP_004308.2	-	crc64:F4861424C8443B58	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:aCn3loYoSVWfy5Tb5i+MsOHcUEo559292	rogid:j2jKZb3MH8Bd3hnoQhDO6bjbyxI9606	intact-crc:086E0E2B27E9DA65|rigid:o1R26f3SK3+5prTF5ubQbsjwHwU	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O43765	uniprotkb:P35176	intact:EBI-347996|ensembl:ENSP00000221566|ensembl:ENSP00000503397|ensembl:ENSP00000504495|uniprotkb:Q9BTZ9|intact:EBI-1045243|uniprotkb:Q6FIA9|uniprotkb:D6W610	intact:EBI-5458|uniprotkb:D6VST3|ensemblfungi:YDR304C	psi-mi:sgta_human(display_long)|uniprotkb:SGTA(gene name)|psi-mi:SGTA(display_short)|uniprotkb:SGT(gene name synonym)|uniprotkb:Alpha-SGT(gene name synonym)|uniprotkb:Vpu-binding protein(gene name synonym)|uniprotkb:SGT1(gene name synonym)	psi-mi:cypd_yeast(display_long)|uniprotkb:CPR5(gene name)|psi-mi:CPR5(display_short)|uniprotkb:YDR304C(locus name)|uniprotkb:D9740.14(orf name)|uniprotkb:CYP5(gene name synonym)|uniprotkb:CYPD(gene name synonym)|uniprotkb:Cyclophilin D(gene name synonym)|uniprotkb:Rotamase D(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549356|imex:IM-24995-2910	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:4CPG|rcsb pdb:4GOD|rcsb pdb:4GOE|rcsb pdb:4GOF|reactome:R-HSA-9609523|rcsb pdb:2VYI|ensembl:ENSG00000104969(gene)|ensembl:ENST00000221566(transcript)|ensembl:ENST00000676943(transcript)|ensembl:ENST00000677149(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072380"(TRC complex)|go:"GO:0098850"(extrinsic component of synaptic vesicle membrane)|go:"GO:1903070"(negative regulation of ER-associated ubiquitin-dependent protein catabolic process)|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)|go:"GO:1903646"(positive regulation of chaperone-mediated protein folding)|go:"GO:1904288"(BAT3 complex binding)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR032374|mint:O43765|refseq:XP_011526480.1|refseq:NP_003012.1	sgd:S000002712|refseq:NP_010590.3|dip:DIP-5222N|mint:P35176|ensemblfungi:YDR304C(gene)|ensemblfungi:YDR304C_mRNA(transcript)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006457"(protein folding)|go:"GO:0016018"(cyclosporin A binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|interpro:IPR020892|interpro:IPR029000	-	-	crc64:F4861424C8443B58	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:r/Cyj4UJk/cS8QdrbjhTZMPCigI9606	rogid:aCn3loYoSVWfy5Tb5i+MsOHcUEo559292	intact-crc:BF515309F894F9C9|rigid:qQgJzAnQ9luCe7HRjqJy0vldZ2A	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P35520	uniprotkb:P32502	intact:EBI-740135|uniprotkb:Q99425|uniprotkb:Q9BWC5|uniprotkb:B2R993|uniprotkb:D3DSK4|intact:EBI-14245939|ensembl:ENSP00000344460|ensembl:ENSP00000352643|ensembl:ENSP00000381225|ensembl:ENSP00000381231	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:cbs_human(display_long)|uniprotkb:CBS(gene name)|psi-mi:CBS(display_short)|uniprotkb:Serine sulfhydrase(gene name synonym)|uniprotkb:Beta-thionase(gene name synonym)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549376|imex:IM-24995-2915	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000062.1|refseq:NP_001171479.1|refseq:NP_001171480.1|ensembl:ENSG00000160200(gene)|ensembl:ENST00000352178(transcript)|ensembl:ENST00000359624(transcript)|ensembl:ENST00000398158(transcript)|go:"GO:0004122"(cystathionine beta-synthase activity)|ensembl:ENST00000398165(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006535"(cysteine biosynthetic process from serine)|go:"GO:0006563"(L-serine metabolic process)|go:"GO:0006565"(L-serine catabolic process)|go:"GO:0019343"(cysteine biosynthetic process via cystathionine)|go:"GO:0019344"(cysteine biosynthetic process)|go:"GO:0019346"(transsulfuration)|go:"GO:0019448"(L-cysteine catabolic process)|go:"GO:0019825"(oxygen binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0020037"(heme binding)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042262"(DNA protection)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043418"(homocysteine catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0050421"("nitrite reductase (NO-forming) activity")|go:"GO:0050667"(homocysteine metabolic process)|go:"GO:0070025"(carbon monoxide binding)|go:"GO:0070026"(nitric oxide binding)|go:"GO:0070814"(hydrogen sulfide biosynthetic process)|go:"GO:0072341"(modified amino acid binding)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR001216(Cysteine synthase/cystathionine beta-synthase P-phosphate-binding site)|interpro:IPR001926(Pyridoxal phosphate-dependent enzyme, beta subunit)|interpro:IPR005857(Cystathionine beta-synthase)|interpro:IPR036052|mint:P35520|rcsb pdb:1JBQ|rcsb pdb:1M54|rcsb pdb:4COO|rcsb pdb:4L0D|rcsb pdb:4L27|rcsb pdb:4L28|rcsb pdb:4L3V|rcsb pdb:4PCU|rcsb pdb:4UUU|rcsb pdb:5MMS|reactome:R-HSA-1614603|reactome:R-HSA-2408508|refseq:XP_011528079.1|refseq:XP_011528083.1|refseq:XP_011528084.1|refseq:XP_011544396.1|refseq:XP_011544397.1|refseq:XP_011544399.1|refseq:XP_011544400.1|refseq:XP_011544401.1|refseq:NP_001307227.1|refseq:NP_001308002.1|refseq:XP_016883700.1|refseq:XP_016883701.1|refseq:XP_016883702.1|refseq:XP_016883703.1|refseq:XP_016883704.1|refseq:XP_016883705.1|refseq:XP_016883706.1|refseq:XP_016883707.1|refseq:XP_016883978.1|refseq:XP_016883979.1|refseq:XP_016883980.1|refseq:XP_016883981.1	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731	-	-	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:f9eo0cPOHppVY7Nqejag3YyK18s9606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:697AF1F6C70575DC|rigid:ADANlPLz4St9Yu5ZB2FdFPX9NCA	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P35184	uniprotkb:P14373	intact:EBI-17971|uniprotkb:D6VVU2|ensemblfungi:YIR012W	intact:EBI-719493|uniprotkb:A2BE15|uniprotkb:Q5RJA8|uniprotkb:Q5ST26|uniprotkb:Q6LA73|uniprotkb:Q6NXR9|uniprotkb:Q9BZY6|uniprotkb:Q9UJL3|ensembl:ENSP00000383555|ensembl:ENSP00000392787|ensembl:ENSP00000405229|ensembl:ENSP00000414793|ensembl:ENSP00000366404	psi-mi:sqt1_yeast(display_long)|uniprotkb:YIB12W(orf name)|uniprotkb:YIR012W(locus name)|uniprotkb:SQT1(gene name)|psi-mi:SQT1(display_short)	psi-mi:tri27_human(display_long)|uniprotkb:TRIM27(gene name)|psi-mi:TRIM27(display_short)|uniprotkb:RNF76(gene name synonym)|uniprotkb:RFP(gene name synonym)|uniprotkb:Ret finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 27(gene name synonym)|uniprotkb:RING finger protein 76(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM27(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549364|imex:IM-24995-2912	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012277.1|sgd:S000001451|ensemblfungi:YIR012W_mRNA(transcript)|ensemblfungi:YIR012W(gene)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|rcsb pdb:4ZOV|rcsb pdb:4ZOX|rcsb pdb:5AMS|dip:DIP-2508N|mint:P35184	refseq:NP_006501.1|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0090281"(negative regulation of calcium ion import)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR020457|interpro:IPR035791|interpro:IPR043136|mint:P14373|reactome:R-HSA-3232142|reactome:R-HSA-9635465|reactome:R-HSA-8948751|ensembl:ENSG00000204713(gene)|ensembl:ENSG00000215641(gene)|ensembl:ENSG00000229006(gene)|ensembl:ENSG00000234495(gene)|ensembl:ENSG00000237071(gene)|ensembl:ENST00000377199(transcript)|ensembl:ENST00000400720(transcript)|ensembl:ENST00000431123(transcript)|ensembl:ENST00000435528(transcript)|ensembl:ENST00000437160(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001650"(fibrillar center)|go:"GO:0002820"(negative regulation of adaptive immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)	-	crc64:981D566076B0C881	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:u/Q5uAjR85ZD3op0nHiN20IVCLY559292	rogid:dsfH5OUghD8KSaTz1SFw9OYVTK49606	intact-crc:5B001B3008C943F3|rigid:yNAYNi8fy6ovb44xWu73iHfwTu8	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P35184	uniprotkb:Q08379	intact:EBI-17971|uniprotkb:D6VVU2|ensemblfungi:YIR012W	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	psi-mi:sqt1_yeast(display_long)|uniprotkb:YIB12W(orf name)|uniprotkb:YIR012W(locus name)|uniprotkb:SQT1(gene name)|psi-mi:SQT1(display_short)	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549368|imex:IM-24995-2913	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012277.1|sgd:S000001451|ensemblfungi:YIR012W_mRNA(transcript)|ensemblfungi:YIR012W(gene)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|rcsb pdb:4ZOV|rcsb pdb:4ZOX|rcsb pdb:5AMS|dip:DIP-2508N|mint:P35184	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N	-	crc64:981D566076B0C881	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2017/05/26	rogid:u/Q5uAjR85ZD3op0nHiN20IVCLY559292	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	intact-crc:81A5986DFD6E29E7|rigid:4cdxPE30cCZSDpIJI9J3f+4xJLw	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P32449	uniprotkb:P35520	intact:EBI-2915|uniprotkb:D6VQP5|ensemblfungi:YBR249C	intact:EBI-740135|uniprotkb:Q99425|uniprotkb:Q9BWC5|uniprotkb:B2R993|uniprotkb:D3DSK4|intact:EBI-14245939|ensembl:ENSP00000344460|ensembl:ENSP00000352643|ensembl:ENSP00000381225|ensembl:ENSP00000381231	psi-mi:arog_yeast(display_long)|uniprotkb:ARO4(gene name)|psi-mi:ARO4(display_short)|uniprotkb:YBR249C(locus name)|uniprotkb:YBR1701(orf name)|uniprotkb:Phospho-2-keto-3-deoxyheptonate aldolase(gene name synonym)|uniprotkb:3-deoxy-D-arabino-heptulosonate 7-phosphate synthase(gene name synonym)|uniprotkb:DAHP synthase(gene name synonym)	psi-mi:cbs_human(display_long)|uniprotkb:CBS(gene name)|psi-mi:CBS(display_short)|uniprotkb:Serine sulfhydrase(gene name synonym)|uniprotkb:Beta-thionase(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549372|imex:IM-24995-2914	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009808.1|sgd:S000000453|dip:DIP-4175N|mint:P32449|ensemblfungi:YBR249C(gene)|ensemblfungi:YBR249C_mRNA(transcript)|go:"GO:0003849"(3-deoxy-7-phosphoheptulonate synthase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008652"(cellular amino acid biosynthetic process)|go:"GO:0009073"(aromatic amino acid family biosynthetic process)|go:"GO:0009423"(chorismate biosynthetic process)|interpro:IPR006218(DAHP synthetase I/KDSA)|interpro:IPR006219(DHAP synthase, class 1)|interpro:IPR013785(Aldolase-type TIM barrel)|rcsb pdb:1HFB|rcsb pdb:1OAB|rcsb pdb:1OF6|rcsb pdb:1OF8|rcsb pdb:1OFA|rcsb pdb:1OFB|rcsb pdb:1OFO|rcsb pdb:1OFP|rcsb pdb:1OFQ|rcsb pdb:1OFR|rcsb pdb:1OG0	refseq:NP_000062.1|refseq:NP_001171479.1|refseq:NP_001171480.1|ensembl:ENSG00000160200(gene)|ensembl:ENST00000352178(transcript)|ensembl:ENST00000359624(transcript)|ensembl:ENST00000398158(transcript)|go:"GO:0004122"(cystathionine beta-synthase activity)|ensembl:ENST00000398165(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006535"(cysteine biosynthetic process from serine)|go:"GO:0006563"(L-serine metabolic process)|go:"GO:0006565"(L-serine catabolic process)|go:"GO:0019343"(cysteine biosynthetic process via cystathionine)|go:"GO:0019344"(cysteine biosynthetic process)|go:"GO:0019346"(transsulfuration)|go:"GO:0019448"(L-cysteine catabolic process)|go:"GO:0019825"(oxygen binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0020037"(heme binding)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042262"(DNA protection)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043418"(homocysteine catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0050421"("nitrite reductase (NO-forming) activity")|go:"GO:0050667"(homocysteine metabolic process)|go:"GO:0070025"(carbon monoxide binding)|go:"GO:0070026"(nitric oxide binding)|go:"GO:0070814"(hydrogen sulfide biosynthetic process)|go:"GO:0072341"(modified amino acid binding)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR001216(Cysteine synthase/cystathionine beta-synthase P-phosphate-binding site)|interpro:IPR001926(Pyridoxal phosphate-dependent enzyme, beta subunit)|interpro:IPR005857(Cystathionine beta-synthase)|interpro:IPR036052|mint:P35520|rcsb pdb:1JBQ|rcsb pdb:1M54|rcsb pdb:4COO|rcsb pdb:4L0D|rcsb pdb:4L27|rcsb pdb:4L28|rcsb pdb:4L3V|rcsb pdb:4PCU|rcsb pdb:4UUU|rcsb pdb:5MMS|reactome:R-HSA-1614603|reactome:R-HSA-2408508|refseq:XP_011528079.1|refseq:XP_011528083.1|refseq:XP_011528084.1|refseq:XP_011544396.1|refseq:XP_011544397.1|refseq:XP_011544399.1|refseq:XP_011544400.1|refseq:XP_011544401.1|refseq:NP_001307227.1|refseq:NP_001308002.1|refseq:XP_016883700.1|refseq:XP_016883701.1|refseq:XP_016883702.1|refseq:XP_016883703.1|refseq:XP_016883704.1|refseq:XP_016883705.1|refseq:XP_016883706.1|refseq:XP_016883707.1|refseq:XP_016883978.1|refseq:XP_016883979.1|refseq:XP_016883980.1|refseq:XP_016883981.1	-	crc64:594ED48F24175979	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:y1YXaSHJozc5Q77Q8LqQ61IA6Lw559292	rogid:f9eo0cPOHppVY7Nqejag3YyK18s9606	intact-crc:910CF6FC0C318829|rigid:ZtvOayfnVEJ2d3guFmvfzRJhXps	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O43765	uniprotkb:P36057	intact:EBI-347996|ensembl:ENSP00000221566|ensembl:ENSP00000503397|ensembl:ENSP00000504495|uniprotkb:Q9BTZ9|intact:EBI-1045243|uniprotkb:Q6FIA9|uniprotkb:D6W610	intact:EBI-18091|uniprotkb:D6VX44|ensemblfungi:YKL154W	psi-mi:sgta_human(display_long)|uniprotkb:SGTA(gene name)|psi-mi:SGTA(display_short)|uniprotkb:SGT(gene name synonym)|uniprotkb:Alpha-SGT(gene name synonym)|uniprotkb:Vpu-binding protein(gene name synonym)|uniprotkb:SGT1(gene name synonym)	psi-mi:srpb_yeast(display_long)|uniprotkb:SRP102(gene name)|psi-mi:SRP102(display_short)|uniprotkb:YKL609(orf name)|uniprotkb:YKL154W(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549396|imex:IM-24995-2920	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:4CPG|rcsb pdb:4GOD|rcsb pdb:4GOE|rcsb pdb:4GOF|reactome:R-HSA-9609523|rcsb pdb:2VYI|ensembl:ENSG00000104969(gene)|ensembl:ENST00000221566(transcript)|ensembl:ENST00000676943(transcript)|ensembl:ENST00000677149(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072380"(TRC complex)|go:"GO:0098850"(extrinsic component of synaptic vesicle membrane)|go:"GO:1903070"(negative regulation of ER-associated ubiquitin-dependent protein catabolic process)|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)|go:"GO:1903646"(positive regulation of chaperone-mediated protein folding)|go:"GO:1904288"(BAT3 complex binding)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR032374|mint:O43765|refseq:XP_011526480.1|refseq:NP_003012.1	refseq:NP_012768.1|sgd:S000001637|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045047"(protein targeting to ER)|interpro:IPR019009|interpro:IPR027417|rcsb pdb:1NRJ|rcsb pdb:2GED|ensemblfungi:YKL154W(gene)|ensemblfungi:YKL154W_mRNA(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005047"(signal recognition particle binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005785"(signal recognition particle receptor complex)|dip:DIP-4753N	-	-	crc64:EA4AE9126B2A04B5	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:r/Cyj4UJk/cS8QdrbjhTZMPCigI9606	rogid:PWBNmZgucFpCtOusxQ3OU1ZvAQ4559292	intact-crc:6CF65D4D659CD399|rigid:5IGU5+F3p/NfHYJeS33OkYCUrb8	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P36009	uniprotkb:P19012	intact:EBI-5844|ensemblfungi:YKL078W|uniprotkb:Q07040|uniprotkb:D6VXK9	intact:EBI-739566|uniprotkb:Q53XV8|uniprotkb:Q9BUG4|uniprotkb:B3KQY1|uniprotkb:B3KRA2|uniprotkb:E0CX14|ensembl:ENSP00000254043|ensembl:ENSP00000377546	psi-mi:dhr2_yeast(display_long)|uniprotkb:DHR2(gene name)|psi-mi:DHR2(display_short)|uniprotkb:YKL078W(locus name)|uniprotkb:YKL408(orf name)|uniprotkb:DEAH box RNA helicase DHR2(gene name synonym)|uniprotkb:Helicase JA2(gene name synonym)	psi-mi:k1c15_human(display_long)|uniprotkb:KRT15(gene name)|psi-mi:KRT15(display_short)|uniprotkb:KRTB(gene name synonym)|uniprotkb:Cytokeratin-15(gene name synonym)|uniprotkb:Keratin-15(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549392|imex:IM-24995-2919	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YKL078W(gene)|ensemblfungi:YKL078W_mRNA(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|refseq:NP_012845.1|sgd:S000001561|dip:DIP-6424N|mint:P36009|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417	refseq:NP_002266.2|ensembl:ENSG00000171346(gene)|ensembl:ENST00000254043(transcript)|ensembl:ENST00000393976(transcript)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0008544"(epidermis development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097110"(scaffold protein binding)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR039008|mint:P19012|reactome:R-HSA-6805567|reactome:R-HSA-6809371	-	crc64:AAFA78B5F6215D89	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:UneKv9+4eIsC09fOzm8AvKCOCVs559292	rogid:WrZQBYQvrWcfrR5ojWXrXp6spPE9606	intact-crc:7A793FB2AF05FFFF|rigid:NaREkejE2qJ2se3b6PCZiveu60Q	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P35719	uniprotkb:O95273	intact:EBI-16255|ensemblfungi:YKL142W|uniprotkb:D6VX54	intact:EBI-748961|uniprotkb:A8K3Q0|uniprotkb:A8K3U2|uniprotkb:Q6ZQN9|uniprotkb:Q7Z519|uniprotkb:Q8NBS7|uniprotkb:Q8NBY2|uniprotkb:Q9NS19|uniprotkb:Q9NYH3|uniprotkb:Q9UHX9|ensembl:ENSP00000300213	psi-mi:mrp8_yeast(display_long)|uniprotkb:MRP8(gene name)|psi-mi:MRP8(display_short)|uniprotkb:YKL3(orf name)|uniprotkb:YKL142W(locus name)	psi-mi:ccdb1_human(display_long)|uniprotkb:Grap2 and cyclin-D-interacting protein(gene name synonym)|uniprotkb:Human homolog of Maid(gene name synonym)|uniprotkb:CCNDBP1(gene name)|psi-mi:CCNDBP1(display_short)|uniprotkb:DIP1(gene name synonym)|uniprotkb:GCIP(gene name synonym)|uniprotkb:HHM(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549380|imex:IM-24995-2916	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012780.1|sgd:S000001625|ensemblfungi:YKL142W(gene)|go:"GO:0005737"(cytoplasm)|interpro:IPR012917(Ribosomal protein MRP8, mitochondrial)|ensemblfungi:YKL142W_mRNA(transcript)|dip:DIP-1437N|mint:P35719	refseq:NP_036274.3|ensembl:ENSG00000166946(gene)|ensembl:ENST00000300213(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0016604"(nuclear body)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR026907|mint:O95273|rcsb pdb:3AY5	-	crc64:CCAD54B7581A5ABE	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:xrv86SZgOYjf+CaLkNdme45DC9s559292	rogid:Vi9aoFc+Mov6P3X6KGmsTxXqxvM9606	intact-crc:69A5C17568E12CA9|rigid:4erpV7VkNjR/NOhLjNIqNdj0S1g	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:A0A024R4Q5	uniprotkb:P35719	intact:EBI-11527449	intact:EBI-16255|ensemblfungi:YKL142W|uniprotkb:D6VX54	psi-mi:a0a024r4q5_human(display_long)|uniprotkb:hCG_20946(orf name)|uniprotkb:TFPT(gene name)|psi-mi:TFPT(display_short)	psi-mi:mrp8_yeast(display_long)|uniprotkb:MRP8(gene name)|psi-mi:MRP8(display_short)|uniprotkb:YKL3(orf name)|uniprotkb:YKL142W(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549384|imex:IM-24995-2917	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_037474.1|interpro:IPR033555|go:"GO:0005654"(nucleoplasm)|go:"GO:0006915"(apoptotic process)	refseq:NP_012780.1|sgd:S000001625|ensemblfungi:YKL142W(gene)|go:"GO:0005737"(cytoplasm)|interpro:IPR012917(Ribosomal protein MRP8, mitochondrial)|ensemblfungi:YKL142W_mRNA(transcript)|dip:DIP-1437N|mint:P35719	-	-	crc64:CCAD54B7581A5ABE	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:juI/3gZemjc0hnXDJ9J+bIQ9pBw9606	rogid:xrv86SZgOYjf+CaLkNdme45DC9s559292	intact-crc:8D45AF0A32A28370|rigid:t2kvQdRlFcuC5B3VyNAvAD0B5P0	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P07954	uniprotkb:P35719	intact:EBI-1050358|uniprotkb:B1ANK7|ensembl:ENSP00000355518	intact:EBI-16255|ensemblfungi:YKL142W|uniprotkb:D6VX54	psi-mi:fumh_human(display_long)|uniprotkb:FH(gene name)|psi-mi:FH(display_short)	psi-mi:mrp8_yeast(display_long)|uniprotkb:MRP8(gene name)|psi-mi:MRP8(display_short)|uniprotkb:YKL3(orf name)|uniprotkb:YKL142W(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549388|imex:IM-24995-2918	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000134.2|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006106"(fumarate metabolic process)|go:"GO:0006108"(malate metabolic process)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042393"(histone binding)|go:"GO:0045239"(tricarboxylic acid cycle enzyme complex)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0070062"(extracellular exosome)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR000362(Fumarate lyase)|interpro:IPR005677(Fumarate hydratase, class II)|ensembl:ENSG00000091483(gene)|interpro:IPR008948(L-Aspartase-like)|interpro:IPR018951|ensembl:ENST00000366560(transcript)|interpro:IPR020557|interpro:IPR022761|go:"GO:0000050"(urea cycle)|interpro:IPR024083|mint:P07954|rcsb pdb:3E04|go:"GO:0000415"(negative regulation of histone H3-K36 methylation)|rcsb pdb:5D6B|go:"GO:0000821"(regulation of arginine metabolic process)|rcsb pdb:5UPP|rcsb pdb:6EBT|rcsb pdb:6V8F|rcsb pdb:6VBE|go:"GO:0004333"(fumarate hydratase activity)|reactome:R-HSA-71403|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|dip:DIP-46920N	refseq:NP_012780.1|sgd:S000001625|ensemblfungi:YKL142W(gene)|go:"GO:0005737"(cytoplasm)|interpro:IPR012917(Ribosomal protein MRP8, mitochondrial)|ensemblfungi:YKL142W_mRNA(transcript)|dip:DIP-1437N|mint:P35719	-	-	crc64:CCAD54B7581A5ABE	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:Jukx6wt0vi49nxgaTzdz5x1Q2Mc9606	rogid:xrv86SZgOYjf+CaLkNdme45DC9s559292	intact-crc:96D103E15FADADA7|rigid:quZA2L8oYW5/rFS9odvmcSs3UZc	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q08379	uniprotkb:P36084	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	intact:EBI-11612|ensemblfungi:YKL074C|uniprotkb:D6VXL2	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:mud2_yeast(display_long)|uniprotkb:MUD2(gene name)|psi-mi:MUD2(display_short)|uniprotkb:YKL358(orf name)|uniprotkb:YKL074C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549408|imex:IM-24995-2923	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N	go:"GO:0000243"(commitment complex)|go:"GO:0000348"(mRNA branch site recognition)|go:"GO:0003729"(mRNA binding)|go:"GO:0008187"(poly-pyrimidine tract binding)|go:"GO:0016607"(nuclear speck)|ensemblfungi:YKL074C(gene)|go:"GO:0030628"(pre-mRNA 3'-splice site binding)|go:"GO:0045131"(pre-mRNA branch point binding)|go:"GO:0071004"(U2-type prespliceosome)|ensemblfungi:YKL074C_mRNA(transcript)|go:"GO:0089701"(U2AF complex)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|refseq:NP_012849.1|sgd:S000001557|mint:P36084|dip:DIP-758N	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2017/05/26	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	rogid:l/aBULMxdezuufNxUE5qqnYEN1Y559292	intact-crc:307AB9A87C5628AE|rigid:GOJOGcJuewHTPD3FhWtNjgReEgU	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P36084	uniprotkb:O14641	intact:EBI-11612|ensemblfungi:YKL074C|uniprotkb:D6VXL2	intact:EBI-740850|ensembl:ENSP00000005340|uniprotkb:Q53XM0|uniprotkb:D3DTN3	psi-mi:mud2_yeast(display_long)|uniprotkb:MUD2(gene name)|psi-mi:MUD2(display_short)|uniprotkb:YKL358(orf name)|uniprotkb:YKL074C(locus name)	psi-mi:dvl2_human(display_long)|uniprotkb:DSH homolog 2(gene name synonym)|uniprotkb:DVL2(gene name)|psi-mi:DVL2(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549400|imex:IM-24995-2921	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0000243"(commitment complex)|go:"GO:0000348"(mRNA branch site recognition)|go:"GO:0003729"(mRNA binding)|go:"GO:0008187"(poly-pyrimidine tract binding)|go:"GO:0016607"(nuclear speck)|ensemblfungi:YKL074C(gene)|go:"GO:0030628"(pre-mRNA 3'-splice site binding)|go:"GO:0045131"(pre-mRNA branch point binding)|go:"GO:0071004"(U2-type prespliceosome)|ensemblfungi:YKL074C_mRNA(transcript)|go:"GO:0089701"(U2AF complex)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|refseq:NP_012849.1|sgd:S000001557|mint:P36084|dip:DIP-758N	refseq:NP_004413.1|ensembl:ENSG00000004975(gene)|ensembl:ENST00000005340(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005109"(frizzled binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0007507"(heart development)|go:"GO:0016235"(aggresome)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044340"(canonical Wnt signaling pathway involved in regulation of cell proliferation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0150012"(positive regulation of neuron projection arborization)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008341(Dishevelled-2 region)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:O14641|rcsb pdb:2REY|rcsb pdb:3CBX|rcsb pdb:3CBY|rcsb pdb:3CBZ|rcsb pdb:3CC0|rcsb pdb:4WIP|rcsb pdb:5LNP|rcsb pdb:5SUY|rcsb pdb:5SUZ|rcsb pdb:6IW3|rcsb pdb:6JCK|reactome:R-HSA-201681|reactome:R-HSA-201688|reactome:R-HSA-2028269|reactome:R-HSA-4086400|reactome:R-HSA-4608870|reactome:R-HSA-4641258|reactome:R-HSA-4641262|reactome:R-HSA-5099900|reactome:R-HSA-5368598|reactome:R-HSA-5663220|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9673324|ensembl:ENSP00000005340|dip:DIP-34433N	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:l/aBULMxdezuufNxUE5qqnYEN1Y559292	rogid:2Vdc8oRnT4Mz/j+EXQXrL3AszOc9606	intact-crc:6B35DAFAF75AB703|rigid:cAJUN1S7/U2jmncbEaTbGVNcAVk	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P36084	uniprotkb:Q8N5R6	intact:EBI-11612|ensemblfungi:YKL074C|uniprotkb:D6VXL2	intact:EBI-740841|intact:EBI-953781|uniprotkb:B3KQ49|uniprotkb:A8K3U4|uniprotkb:A8MPQ6|uniprotkb:A8MV61|uniprotkb:A8MVU9|uniprotkb:Q9H5Q6|uniprotkb:Q8TAX6|intact:EBI-2320546|intact:EBI-11522976	psi-mi:mud2_yeast(display_long)|uniprotkb:MUD2(gene name)|psi-mi:MUD2(display_short)|uniprotkb:YKL358(orf name)|uniprotkb:YKL074C(locus name)	psi-mi:ccd33_human(display_long)|uniprotkb:CCDC33(gene name)|psi-mi:CCDC33(display_short)|uniprotkb:Cancer/testis antigen 61(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549404|imex:IM-24995-2922	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0000243"(commitment complex)|go:"GO:0000348"(mRNA branch site recognition)|go:"GO:0003729"(mRNA binding)|go:"GO:0008187"(poly-pyrimidine tract binding)|go:"GO:0016607"(nuclear speck)|ensemblfungi:YKL074C(gene)|go:"GO:0030628"(pre-mRNA 3'-splice site binding)|go:"GO:0045131"(pre-mRNA branch point binding)|go:"GO:0071004"(U2-type prespliceosome)|ensemblfungi:YKL074C_mRNA(transcript)|go:"GO:0089701"(U2AF complex)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|refseq:NP_012849.1|sgd:S000001557|mint:P36084|dip:DIP-758N	refseq:NP_079331.3|interpro:IPR000008(C2 calcium-dependent membrane targeting)|go:"GO:0005777"(peroxisome)|refseq:NP_001274110.1|refseq:NP_877592.2|mint:Q8N5R6|interpro:IPR035892|interpro:IPR039889	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2021/11/30	rogid:l/aBULMxdezuufNxUE5qqnYEN1Y559292	rogid:eEIn7pQyfdHWx8TeLJpYy0i/gww9606	intact-crc:F4B5F30A0B3EECAC|rigid:9jA2zOpeNU+zSpP2ttF0RE5qAYg	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P31384	uniprotkb:P37198	intact:EBI-4396|uniprotkb:D6VPJ7|ensemblfungi:YAL021C	intact:EBI-347978|intact:EBI-28983799|ensembl:ENSP00000305503|ensembl:ENSP00000407331|ensembl:ENSP00000471191|ensembl:ENSP00000473192|uniprotkb:Q6GTM2|uniprotkb:Q503A4|uniprotkb:Q96C43|uniprotkb:Q9NSL1|uniprotkb:B3KWU5	psi-mi:ccr4_yeast(display_long)|uniprotkb:CCR4(gene name)|psi-mi:CCR4(display_short)|uniprotkb:Carbon catabolite repressor protein 4(gene name synonym)|uniprotkb:Cytoplasmic deadenylase(gene name synonym)|uniprotkb:Glucose-repressible alcohol dehydrogenase transcriptional effector(gene name synonym)|uniprotkb:FUN27(orf name)|uniprotkb:YAL021C(locus name)	psi-mi:nup62_human(display_long)|uniprotkb:NUP62(gene name)|psi-mi:NUP62(display_short)|uniprotkb:62 kDa nucleoporin(gene name synonym)|uniprotkb:Nucleoporin Nup62(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549424|imex:IM-24995-2927	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009381.1|sgd:S000000019|dip:DIP-2522N|mint:P31384|ensemblfungi:YAL021C(gene)|ensemblfungi:YAL021C_mRNA(transcript)|go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0004535"("poly(A)-specific ribonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0007089"(traversing start control point of mitotic cell cycle)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0046872"(metal ion binding)|go:"GO:0048478"(replication fork protection)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR005135(Endonuclease/exonuclease/phosphatase)|interpro:IPR025875|interpro:IPR032675|interpro:IPR036691|rcsb pdb:4B8C	refseq:NP_714941.1|ensembl:ENSG00000213024(gene)|ensembl:ENST00000352066(transcript)|ensembl:ENST00000422090(transcript)|ensembl:ENST00000596217(transcript)|ensembl:ENST00000597029(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005642"(annulate lamellae)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007100"(mitotic centrosome separation)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007569"(cell aging)|go:"GO:0008219"(cell death)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0003682"(chromatin binding)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0019894"(kinesin binding)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042306"(regulation of protein import into nucleus)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043069"(negative regulation of programmed cell death)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045742"(positive regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046578"(regulation of Ras protein signal transduction)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0046601"(positive regulation of centriole replication)|go:"GO:0051028"(mRNA transport)|go:"GO:0051425"(PTB domain binding)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0072686"(mitotic spindle)|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|go:"GO:0090543"(Flemming body)|go:"GO:0098534"(centriole assembly)|go:"GO:1903438"(positive regulation of mitotic cytokinetic process)|go:"GO:1904781"(positive regulation of protein localization to centrosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR007758(Nucleoporin, Nsp1-like, C-terminal)|interpro:IPR026010|interpro:IPR033072|mint:P37198|rcsb pdb:2H4D|rcsb pdb:5IJN|rcsb pdb:5IJO|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|refseq:NP_714940.1|refseq:NP_001180286.1|refseq:NP_036478.2|refseq:NP_057637.2|ensembl:ENSP00000305503|ensembl:ENSP00000407331|ensembl:ENSP00000471191|ensembl:ENSP00000473192|dip:DIP-29749N	-	crc64:5CDB2E8FEDDBEF6F	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:f5gxp32WdxKuHQnE8O9/EhhA3Gw559292	rogid:v7mvKvTtVEnLMwcpUZIcdAzge009606	intact-crc:5607105DC333F542|rigid:LxPYRKS68Nq0z2/lCQwYo7kiCB4	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P36406	uniprotkb:P32902	intact:EBI-740098|uniprotkb:Q9BZY4|uniprotkb:Q9BZY5|ensembl:ENSP00000231524	intact:EBI-16248|ensemblfungi:YHL004W|uniprotkb:D3DKR0	psi-mi:tri23_human(display_long)|uniprotkb:TRIM23(gene name)|psi-mi:TRIM23(display_short)|uniprotkb:ARD1(gene name synonym)|uniprotkb:ARFD1(gene name synonym)|uniprotkb:RNF46(gene name synonym)|uniprotkb:ADP-ribosylation factor domain-containing protein 1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 23(gene name synonym)|uniprotkb:RING finger protein 46(gene name synonym)|uniprotkb:GTP-binding protein ARD-1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM23(gene name synonym)	psi-mi:rt04_yeast(display_long)|uniprotkb:MRP4(gene name)|psi-mi:MRP4(display_short)|uniprotkb:MRP4A(gene name synonym)|uniprotkb:Mitochondrial small ribosomal subunit protein uS2m(gene name synonym)|uniprotkb:YHL004W(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549420|imex:IM-24995-2926	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001647.1|refseq:NP_150230.1|refseq:NP_150231.1|refseq:XP_016864933.1|ensembl:ENSG00000113595(gene)|ensembl:ENST00000231524(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019003"(GDP binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR017907|interpro:IPR027417|mint:P36406|rcsb pdb:5VZV|rcsb pdb:5VZW	ensemblfungi:YHL004W(gene)|ensemblfungi:YHL004W_mRNA(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR001865(Ribosomal protein S2)|interpro:IPR005706(Ribosomal protein S2, bacterial-type)|interpro:IPR018130|interpro:IPR023591|rcsb pdb:5MRC|rcsb pdb:5MRE|rcsb pdb:5MRF|refseq:NP_011859.1|sgd:S000000996|dip:DIP-5035N|mint:P32902	-	-	crc64:81A1CB33134BC559	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:skGAO7nm9YvqJGWF6fzjtn5CWuc9606	rogid:BlL3W6HUN+uAKF/AxwlV1zT5YZQ559292	intact-crc:608DC7461EF93033|rigid:B+YCiMtTsROETnJFJlOLGrc0lvM	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q08379	uniprotkb:P36149	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	intact:EBI-3567|uniprotkb:D6VXC9|ensemblfungi:YKR068C	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:bet3_yeast(display_long)|uniprotkb:YKR068C(locus name)|uniprotkb:BET3(gene name)|psi-mi:BET3(display_short)|uniprotkb:Transport protein particle 22 kDa subunit(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549416|imex:IM-24995-2925	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N	refseq:NP_012994.1|sgd:S000001776|dip:DIP-1710N|mint:P36149|ensemblfungi:YKR068C(gene)|ensemblfungi:YKR068C_mRNA(transcript)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0030008"(TRAPP complex)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0033106"(cis-Golgi network membrane)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:1990070"(TRAPPI protein complex)|go:"GO:1990071"(TRAPPII protein complex)|go:"GO:1990072"(TRAPPIII protein complex)|interpro:IPR007194("Transport protein particle (TRAPP) component, Bet3")|interpro:IPR016721(TRAPP I complex, Bet3)|interpro:IPR024096|rcsb pdb:3CUE|rcsb pdb:7KMT|reactome:R-SCE-204005|reactome:R-SCE-8876198	-	-	crc64:C802D8A3563DE82B	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2017/05/26	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	rogid:XN0vyDhpSkOFxu+sgthTqABoSxM559292	intact-crc:06543F37EA5D4B9C|rigid:pgPBy01O66tFxjGKHTFMly7kMfQ	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P19012	uniprotkb:P36086	intact:EBI-739566|uniprotkb:Q53XV8|uniprotkb:Q9BUG4|uniprotkb:B3KQY1|uniprotkb:B3KRA2|uniprotkb:E0CX14|ensembl:ENSP00000254043|ensembl:ENSP00000377546	intact:EBI-2343631|uniprotkb:D6VXL5|ensemblfungi:YKL071W	psi-mi:k1c15_human(display_long)|uniprotkb:KRT15(gene name)|psi-mi:KRT15(display_short)|uniprotkb:KRTB(gene name synonym)|uniprotkb:Cytokeratin-15(gene name synonym)|uniprotkb:Keratin-15(gene name synonym)	psi-mi:ykh1_yeast(display_long)|uniprotkb:YKL071W(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549412|imex:IM-24995-2924	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002266.2|ensembl:ENSG00000171346(gene)|ensembl:ENST00000254043(transcript)|ensembl:ENST00000393976(transcript)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0008544"(epidermis development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097110"(scaffold protein binding)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR039008|mint:P19012|reactome:R-HSA-6805567|reactome:R-HSA-6809371	interpro:IPR002347(Glucose/ribitol dehydrogenase)|refseq:NP_012852.1|sgd:S000001554|interpro:IPR036291|ensemblfungi:YKL071W(gene)|ensemblfungi:YKL071W_mRNA(transcript)|go:"GO:0004022"("alcohol dehydrogenase (NAD+) activity")|go:"GO:0005737"(cytoplasm)|go:"GO:0110095"(cellular detoxification of aldehyde)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:WrZQBYQvrWcfrR5ojWXrXp6spPE9606	rogid:9+aUU4I1T7cAMKJgi1qbDD4t+WM559292	intact-crc:4D2C199E0D661438|rigid:yFBCH6y2fAf8NjyZpokQqbWZ0Lk	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P38128	uniprotkb:Q08379	intact:EBI-17469|uniprotkb:D6VQH6|ensemblfungi:YBR182C	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	psi-mi:smp1_yeast(display_long)|uniprotkb:YBR1245(orf name)|uniprotkb:YBR182C(locus name)|uniprotkb:SMP1(gene name)|psi-mi:SMP1(display_short)	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549444|imex:IM-24995-2932	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009741.3|sgd:S000000386|interpro:IPR002100(Transcription factor, MADS-box)|ensemblfungi:YBR182C(gene)|ensemblfungi:YBR182C_mRNA(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|reactome:R-SCE-525793|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR033896|interpro:IPR036879	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2017/05/26	rogid:+iBP5NzZkrXnslYfo1RDMrlTAIQ559292	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	intact-crc:2E5B52347B63FFFB|rigid:PmM+1BLaqJRaEfEEELirz9uDHbg	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P38128	uniprotkb:P14373	intact:EBI-17469|uniprotkb:D6VQH6|ensemblfungi:YBR182C	intact:EBI-719493|uniprotkb:A2BE15|uniprotkb:Q5RJA8|uniprotkb:Q5ST26|uniprotkb:Q6LA73|uniprotkb:Q6NXR9|uniprotkb:Q9BZY6|uniprotkb:Q9UJL3|ensembl:ENSP00000383555|ensembl:ENSP00000392787|ensembl:ENSP00000405229|ensembl:ENSP00000414793|ensembl:ENSP00000366404	psi-mi:smp1_yeast(display_long)|uniprotkb:YBR1245(orf name)|uniprotkb:YBR182C(locus name)|uniprotkb:SMP1(gene name)|psi-mi:SMP1(display_short)	psi-mi:tri27_human(display_long)|uniprotkb:TRIM27(gene name)|psi-mi:TRIM27(display_short)|uniprotkb:RNF76(gene name synonym)|uniprotkb:RFP(gene name synonym)|uniprotkb:Ret finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 27(gene name synonym)|uniprotkb:RING finger protein 76(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM27(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549440|imex:IM-24995-2931	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009741.3|sgd:S000000386|interpro:IPR002100(Transcription factor, MADS-box)|ensemblfungi:YBR182C(gene)|ensemblfungi:YBR182C_mRNA(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|reactome:R-SCE-525793|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR033896|interpro:IPR036879	refseq:NP_006501.1|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0090281"(negative regulation of calcium ion import)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR020457|interpro:IPR035791|interpro:IPR043136|mint:P14373|reactome:R-HSA-3232142|reactome:R-HSA-9635465|reactome:R-HSA-8948751|ensembl:ENSG00000204713(gene)|ensembl:ENSG00000215641(gene)|ensembl:ENSG00000229006(gene)|ensembl:ENSG00000234495(gene)|ensembl:ENSG00000237071(gene)|ensembl:ENST00000377199(transcript)|ensembl:ENST00000400720(transcript)|ensembl:ENST00000431123(transcript)|ensembl:ENST00000435528(transcript)|ensembl:ENST00000437160(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001650"(fibrillar center)|go:"GO:0002820"(negative regulation of adaptive immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:+iBP5NzZkrXnslYfo1RDMrlTAIQ559292	rogid:dsfH5OUghD8KSaTz1SFw9OYVTK49606	intact-crc:2891D7114278CD52|rigid:t/9+zqK7MrZBLRPnAemxMVxZ3lo	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P38011	uniprotkb:O43765	intact:EBI-7405|uniprotkb:Q6LAA5|uniprotkb:D6VZT9|ensemblfungi:YMR116C	intact:EBI-347996|ensembl:ENSP00000221566|ensembl:ENSP00000503397|ensembl:ENSP00000504495|uniprotkb:Q9BTZ9|intact:EBI-1045243|uniprotkb:Q6FIA9|uniprotkb:D6W610	psi-mi:gblp_yeast(display_long)|uniprotkb:ASC1(gene name)|psi-mi:ASC1(display_short)|uniprotkb:CPC2(gene name synonym)|uniprotkb:Receptor of activated protein kinase C 1(gene name synonym)|uniprotkb:Receptor for activated C kinase(gene name synonym)|uniprotkb:Small ribosomal subunit protein RACK1(gene name synonym)|uniprotkb:YM9718.15C(orf name)|uniprotkb:YMR116C(locus name)	psi-mi:sgta_human(display_long)|uniprotkb:SGTA(gene name)|psi-mi:SGTA(display_short)|uniprotkb:SGT(gene name synonym)|uniprotkb:Alpha-SGT(gene name synonym)|uniprotkb:Vpu-binding protein(gene name synonym)|uniprotkb:SGT1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549428|imex:IM-24995-2928	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013834.1|sgd:S000004722|mint:P38011|dip:DIP-6465N|ensemblfungi:YMR116C(gene)|ensemblfungi:YMR116C_mRNA(transcript)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001965"(G-protein alpha-subunit binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005092"(GDP-dissociation inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0008104"(protein localization)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0043022"(ribosome binding)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0072344"(rescue of stalled ribosome)|go:"GO:0080135"(regulation of cellular response to stress)|go:"GO:1902660"(negative regulation of glucose mediated signaling pathway)|go:"GO:2001125"(negative regulation of translational frameshifting)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|rcsb pdb:1TRJ|rcsb pdb:3FRX|rcsb pdb:3J6X|rcsb pdb:3J6Y|rcsb pdb:3J77|rcsb pdb:3J78|rcsb pdb:3RFG|rcsb pdb:3RFH|rcsb pdb:4U3M|rcsb pdb:4U3N|rcsb pdb:4U3U|rcsb pdb:4U4N|rcsb pdb:4U4O|rcsb pdb:4U4Q|rcsb pdb:4U4R|rcsb pdb:4U4U|rcsb pdb:4U4Y|rcsb pdb:4U4Z|rcsb pdb:4U50|rcsb pdb:4U51|rcsb pdb:4U52|rcsb pdb:4U53|rcsb pdb:4U55|rcsb pdb:4U56|rcsb pdb:4U6F|rcsb pdb:4V6I|rcsb pdb:4V7R|rcsb pdb:4V88|rcsb pdb:4V8Y|rcsb pdb:4V8Z|rcsb pdb:4V92|rcsb pdb:5DAT|rcsb pdb:5DC3|rcsb pdb:5DGE|rcsb pdb:5DGF|rcsb pdb:5DGV|rcsb pdb:5FCI|rcsb pdb:5FCJ|rcsb pdb:5I4L|rcsb pdb:5JUO|rcsb pdb:5JUP|rcsb pdb:5JUS|rcsb pdb:5JUT|rcsb pdb:5JUU|rcsb pdb:5LYB|rcsb pdb:5M1J|rcsb pdb:5MC6|rcsb pdb:5MEI|rcsb pdb:5NDG|rcsb pdb:5NDV|rcsb pdb:5NDW|rcsb pdb:5OBM|rcsb pdb:5ON6|rcsb pdb:5TBW|rcsb pdb:5TGA|rcsb pdb:5TGM|rcsb pdb:6FAI|rcsb pdb:6GQ1|rcsb pdb:6GQB|rcsb pdb:6GQV|rcsb pdb:6HHQ|rcsb pdb:6I7O|rcsb pdb:6Q8Y|rcsb pdb:6RBE|rcsb pdb:6S47|rcsb pdb:6SNT|rcsb pdb:6SV4|rcsb pdb:6T4Q|rcsb pdb:6T7I|rcsb pdb:6T7T|rcsb pdb:6T83|rcsb pdb:6TB3|rcsb pdb:6TNU|rcsb pdb:6WDR|rcsb pdb:6WOO|rcsb pdb:6XIQ|rcsb pdb:6XIR|rcsb pdb:6Z6J|rcsb pdb:6Z6K|rcsb pdb:6ZCE|rcsb pdb:6ZU9|rcsb pdb:6ZVI|rcsb pdb:7A1G|rcsb pdb:7NRC|rcsb pdb:7NRD|rcsb pdb:7B7D	rcsb pdb:4CPG|rcsb pdb:4GOD|rcsb pdb:4GOE|rcsb pdb:4GOF|reactome:R-HSA-9609523|rcsb pdb:2VYI|ensembl:ENSG00000104969(gene)|ensembl:ENST00000221566(transcript)|ensembl:ENST00000676943(transcript)|ensembl:ENST00000677149(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072380"(TRC complex)|go:"GO:0098850"(extrinsic component of synaptic vesicle membrane)|go:"GO:1903070"(negative regulation of ER-associated ubiquitin-dependent protein catabolic process)|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)|go:"GO:1903646"(positive regulation of chaperone-mediated protein folding)|go:"GO:1904288"(BAT3 complex binding)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR032374|mint:O43765|refseq:XP_011526480.1|refseq:NP_003012.1	-	crc64:B9A5D4959A3C54FB	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:T9ugPN58tGKmSOjRbv1bD1rznH8559292	rogid:r/Cyj4UJk/cS8QdrbjhTZMPCigI9606	intact-crc:D8A6282D26D0A69D|rigid:JI7BWoHcftxx3AMPzyO2ZAnVCjU	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P38128	uniprotkb:O14641	intact:EBI-17469|uniprotkb:D6VQH6|ensemblfungi:YBR182C	intact:EBI-740850|ensembl:ENSP00000005340|uniprotkb:Q53XM0|uniprotkb:D3DTN3	psi-mi:smp1_yeast(display_long)|uniprotkb:YBR1245(orf name)|uniprotkb:YBR182C(locus name)|uniprotkb:SMP1(gene name)|psi-mi:SMP1(display_short)	psi-mi:dvl2_human(display_long)|uniprotkb:DSH homolog 2(gene name synonym)|uniprotkb:DVL2(gene name)|psi-mi:DVL2(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549432|imex:IM-24995-2929	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009741.3|sgd:S000000386|interpro:IPR002100(Transcription factor, MADS-box)|ensemblfungi:YBR182C(gene)|ensemblfungi:YBR182C_mRNA(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|reactome:R-SCE-525793|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR033896|interpro:IPR036879	refseq:NP_004413.1|ensembl:ENSG00000004975(gene)|ensembl:ENST00000005340(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005109"(frizzled binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0007507"(heart development)|go:"GO:0016235"(aggresome)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044340"(canonical Wnt signaling pathway involved in regulation of cell proliferation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0150012"(positive regulation of neuron projection arborization)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008341(Dishevelled-2 region)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:O14641|rcsb pdb:2REY|rcsb pdb:3CBX|rcsb pdb:3CBY|rcsb pdb:3CBZ|rcsb pdb:3CC0|rcsb pdb:4WIP|rcsb pdb:5LNP|rcsb pdb:5SUY|rcsb pdb:5SUZ|rcsb pdb:6IW3|rcsb pdb:6JCK|reactome:R-HSA-201681|reactome:R-HSA-201688|reactome:R-HSA-2028269|reactome:R-HSA-4086400|reactome:R-HSA-4608870|reactome:R-HSA-4641258|reactome:R-HSA-4641262|reactome:R-HSA-5099900|reactome:R-HSA-5368598|reactome:R-HSA-5663220|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9673324|ensembl:ENSP00000005340|dip:DIP-34433N	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:+iBP5NzZkrXnslYfo1RDMrlTAIQ559292	rogid:2Vdc8oRnT4Mz/j+EXQXrL3AszOc9606	intact-crc:84FABFD9B63887A2|rigid:S5InodNAye0yjRMkLGG5XROWwz0	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O00505	uniprotkb:P38128	intact:EBI-358297|intact:EBI-28976892|ensembl:ENSP00000261667|uniprotkb:O00191|uniprotkb:O43195|uniprotkb:Q96AA7|uniprotkb:Q5JVM9|intact:EBI-742146|uniprotkb:Q8IYQ9	intact:EBI-17469|uniprotkb:D6VQH6|ensemblfungi:YBR182C	psi-mi:ima4_human(display_long)|uniprotkb:KPNA3(gene name)|psi-mi:KPNA3(display_short)|uniprotkb:QIP2(gene name synonym)|uniprotkb:Karyopherin subunit alpha-3(gene name synonym)|uniprotkb:SRP1-gamma(gene name synonym)|uniprotkb:Importin alpha Q2(gene name synonym)	psi-mi:smp1_yeast(display_long)|uniprotkb:YBR1245(orf name)|uniprotkb:YBR182C(locus name)|uniprotkb:SMP1(gene name)|psi-mi:SMP1(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549436|imex:IM-24995-2930	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000102753(gene)|ensembl:ENST00000261667(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0043657"(host cell)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0075732"(viral penetration into host nucleus)|interpro:IPR000225(Armadillo)|refseq:NP_002258.2|ensembl:ENSP00000261667|dip:DIP-27586N|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|mint:O00505|reactome:R-HSA-1169408|reactome:R-HSA-168276	refseq:NP_009741.3|sgd:S000000386|interpro:IPR002100(Transcription factor, MADS-box)|ensemblfungi:YBR182C(gene)|ensemblfungi:YBR182C_mRNA(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|reactome:R-SCE-525793|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR033896|interpro:IPR036879	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:kx/oTYWMYG7dhwJHvr1POLD6FTU9606	rogid:+iBP5NzZkrXnslYfo1RDMrlTAIQ559292	intact-crc:F626D1AE955BB0CB|rigid:vW49bMlKUJPjsYRy+VockKtA2Hg	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P38168	uniprotkb:O43765	intact:EBI-21355|ensemblfungi:YBL100C	intact:EBI-347996|ensembl:ENSP00000221566|ensembl:ENSP00000503397|ensembl:ENSP00000504495|uniprotkb:Q9BTZ9|intact:EBI-1045243|uniprotkb:Q6FIA9|uniprotkb:D6W610	psi-mi:ybk0_yeast(display_long)|uniprotkb:YBL0826(orf name)|uniprotkb:YBL100C(locus name)	psi-mi:sgta_human(display_long)|uniprotkb:SGTA(gene name)|psi-mi:SGTA(display_short)|uniprotkb:SGT(gene name synonym)|uniprotkb:Alpha-SGT(gene name synonym)|uniprotkb:Vpu-binding protein(gene name synonym)|uniprotkb:SGT1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549460|imex:IM-24995-2936	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000000196|dip:DIP-5675N|ensemblfungi:YBL100C(gene)|ensemblfungi:YBL100C_mRNA(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)	rcsb pdb:4CPG|rcsb pdb:4GOD|rcsb pdb:4GOE|rcsb pdb:4GOF|reactome:R-HSA-9609523|rcsb pdb:2VYI|ensembl:ENSG00000104969(gene)|ensembl:ENST00000221566(transcript)|ensembl:ENST00000676943(transcript)|ensembl:ENST00000677149(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072380"(TRC complex)|go:"GO:0098850"(extrinsic component of synaptic vesicle membrane)|go:"GO:1903070"(negative regulation of ER-associated ubiquitin-dependent protein catabolic process)|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)|go:"GO:1903646"(positive regulation of chaperone-mediated protein folding)|go:"GO:1904288"(BAT3 complex binding)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR032374|mint:O43765|refseq:XP_011526480.1|refseq:NP_003012.1	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:gPuMXsZP2fRnDh4HhKc6uX1tT8M559292	rogid:r/Cyj4UJk/cS8QdrbjhTZMPCigI9606	intact-crc:1079D71717AC7998|rigid:3OnFZnXxD10R/tRtUYSZvlE7F5g	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P38151	uniprotkb:Q08379	intact:EBI-12968|uniprotkb:D6VQM8|ensemblfungi:YBR233W	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	psi-mi:pbp2_yeast(display_long)|uniprotkb:YBR1531(orf name)|uniprotkb:YBR233W(locus name)|uniprotkb:PBP2(gene name)|psi-mi:PBP2(display_short)	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549448|imex:IM-24995-2933	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000000437|refseq:NP_009792.3|dip:DIP-4947N|ensemblfungi:YBR233W(gene)|ensemblfungi:YBR233W_mRNA(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0051252"(regulation of RNA metabolic process)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR036612	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N	-	crc64:638846509BCE1840	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2017/05/26	rogid:zcN9K+pivnit4l3Cl75wfk5F4VI559292	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	intact-crc:B62FE1733E5026F7|rigid:xQUBfMMwoTlpWhUucmKFmlQ9oAA	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P09012	uniprotkb:P38151	intact:EBI-607085|ensembl:ENSP00000243563	intact:EBI-12968|uniprotkb:D6VQM8|ensemblfungi:YBR233W	psi-mi:snrpa_human(display_long)|uniprotkb:SNRPA(gene name)|psi-mi:SNRPA(display_short)	psi-mi:pbp2_yeast(display_long)|uniprotkb:YBR1531(orf name)|uniprotkb:YBR233W(locus name)|uniprotkb:PBP2(gene name)|psi-mi:PBP2(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549452|imex:IM-24995-2934	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005685"(U1 snRNP)|go:"GO:0030619"(U1 snRNA binding)|ensembl:ENSG00000077312(gene)|go:"GO:0042802"(identical protein binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034407|interpro:IPR034409|interpro:IPR035979|mint:P09012|rcsb pdb:1AUD|ensembl:ENST00000243563(transcript)|rcsb pdb:1DRZ|rcsb pdb:1DZ5|rcsb pdb:1FHT|rcsb pdb:1M5K|rcsb pdb:1M5O|rcsb pdb:1M5P|rcsb pdb:1M5V|rcsb pdb:1NU4|rcsb pdb:1OIA|rcsb pdb:1SJ3|rcsb pdb:1SJ4|rcsb pdb:1SJF|rcsb pdb:1U6B|rcsb pdb:1URN|rcsb pdb:1VBX|rcsb pdb:1VBY|rcsb pdb:1VBZ|rcsb pdb:1VC0|rcsb pdb:1VC5|rcsb pdb:1VC6|rcsb pdb:1ZZN|rcsb pdb:2A3J|rcsb pdb:2NZ4|rcsb pdb:2OIH|rcsb pdb:2OJ3|rcsb pdb:2U1A|rcsb pdb:3BO2|rcsb pdb:3BO3|rcsb pdb:3BO4|rcsb pdb:3CUL|rcsb pdb:3CUN|rcsb pdb:3EGZ|rcsb pdb:3G8S|rcsb pdb:3G8T|rcsb pdb:3G96|rcsb pdb:3G9C|rcsb pdb:3HHN|rcsb pdb:3IIN|rcsb pdb:3IRW|rcsb pdb:3IWN|rcsb pdb:3K0J|rcsb pdb:3L3C|rcsb pdb:3MUM|rcsb pdb:3MUR|rcsb pdb:3MUT|rcsb pdb:3R1H|rcsb pdb:3R1L|rcsb pdb:3UCU|rcsb pdb:3UCZ|rcsb pdb:3UD3|rcsb pdb:3UD4|rcsb pdb:3MUV|rcsb pdb:3UTR|rcsb pdb:4C4W|rcsb pdb:4PR6|rcsb pdb:4PRF|rcsb pdb:4W90|rcsb pdb:4W92|rcsb pdb:3MXH|rcsb pdb:3P49|rcsb pdb:3PGW|rcsb pdb:4YB1|rcsb pdb:5DDO|rcsb pdb:5DDP|rcsb pdb:5DDQ|rcsb pdb:5DDR|rcsb pdb:5FJ4|rcsb pdb:6LAS|rcsb pdb:6LAU|rcsb pdb:6LAX|rcsb pdb:6LAZ|rcsb pdb:6QX9|rcsb pdb:6SQN|rcsb pdb:6SQQ|rcsb pdb:6SQT|rcsb pdb:6SQV|rcsb pdb:6SR7|rcsb pdb:6XH0|rcsb pdb:6XH1|rcsb pdb:6XH2|rcsb pdb:6XH3|rcsb pdb:7AEP|rcsb pdb:7B0Y|rcsb pdb:7D7V|rcsb pdb:7LHX|reactome:R-HSA-72163|refseq:NP_004587.1|dip:DIP-29407N	sgd:S000000437|refseq:NP_009792.3|dip:DIP-4947N|ensemblfungi:YBR233W(gene)|ensemblfungi:YBR233W_mRNA(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0051252"(regulation of RNA metabolic process)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR036612	-	-	crc64:638846509BCE1840	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:BJ9zdDzOPs9JYgU8lErj/maq0AY9606	rogid:zcN9K+pivnit4l3Cl75wfk5F4VI559292	intact-crc:FFF9A941FD4FC798|rigid:VvCgiZmrrXTe79IE0dPM+8vL6Iw	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P38159	uniprotkb:P32505	intact:EBI-743526|ensembl:ENSP00000359645|uniprotkb:Q5JQ67|uniprotkb:Q969R3|uniprotkb:D3DWH0|uniprotkb:E9PG86|uniprotkb:Q8N8Y7|uniprotkb:B4E3U4	intact:EBI-11770|ensemblfungi:YGL122C|uniprotkb:D6VU26	psi-mi:rbmx_human(display_long)|uniprotkb:Glycoprotein p43(gene name synonym)|uniprotkb:RBMX(gene name)|psi-mi:RBMX(display_short)|uniprotkb:HNRPG(gene name synonym)|uniprotkb:RBMXP1(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein G(gene name synonym)	psi-mi:nab2_yeast(display_long)|uniprotkb:YGL122C(locus name)|uniprotkb:NAB2(gene name)|psi-mi:NAB2(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549456|imex:IM-24995-2935	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000147274(gene)|ensembl:ENST00000320676(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000791"(euchromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0044530"(supraspliceosomal complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0006509"(membrane protein ectodomain proteolysis)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012604(RBM1CTR)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|mint:P38159|rcsb pdb:2MB0|rcsb pdb:2MKS|reactome:R-HSA-72163|reactome:R-HSA-72203|reactome:R-HSA-9013418|reactome:R-HSA-9013422|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273|refseq:NP_002130.2|refseq:NP_001158275.1|dip:DIP-34447N	ensemblfungi:YGL122C(gene)|ensemblfungi:YGL122C_mRNA(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0008097"(5S rRNA binding)|go:"GO:0008143"("poly(A) binding")|go:"GO:0008312"(7S RNA binding)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0033204"(ribonuclease P RNA binding)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0046872"(metal ion binding)|go:"GO:1900152"(negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|interpro:IPR021083|interpro:IPR040366|go:"GO:0045945"(positive regulation of transcription by RNA polymerase III)|interpro:IPR041044|interpro:IPR043094|rcsb pdb:2JPS|rcsb pdb:2LHN|rcsb pdb:2V75|rcsb pdb:3LCN|rcsb pdb:3ZJ1|rcsb pdb:3ZJ2|rcsb pdb:4JLQ|rcsb pdb:5L2L|refseq:NP_011393.3|sgd:S000003090|mint:P32505|dip:DIP-1331N	-	-	crc64:40335C3D4658DD91	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:ocCkdy9PxjeVLUQf0tMVCEhFfO89606	rogid:tNdhCVVTRYjqg7BES5wD2Gg4rjw559292	intact-crc:85ED9A0C58217827|rigid:OHmVTY27Tx1ptByqU/vkxddfBgc	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P38234	uniprotkb:Q8N5R6	intact:EBI-21445|uniprotkb:D6VQ51|ensemblfungi:YBR052C	intact:EBI-740841|intact:EBI-953781|uniprotkb:B3KQ49|uniprotkb:A8K3U4|uniprotkb:A8MPQ6|uniprotkb:A8MV61|uniprotkb:A8MVU9|uniprotkb:Q9H5Q6|uniprotkb:Q8TAX6|intact:EBI-2320546|intact:EBI-11522976	psi-mi:rfs1_yeast(display_long)|uniprotkb:YBR052C(locus name)|uniprotkb:YBR0505(orf name)|uniprotkb:RFS1(gene name)|psi-mi:RFS1(display_short)|uniprotkb:RAD55 suppressor protein 1(gene name synonym)	psi-mi:ccd33_human(display_long)|uniprotkb:CCDC33(gene name)|psi-mi:CCDC33(display_short)|uniprotkb:Cancer/testis antigen 61(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549476|imex:IM-24995-2940	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009608.1|sgd:S000000256|mint:P38234|dip:DIP-1761N|ensemblfungi:YBR052C(gene)|ensemblfungi:YBR052C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0010181"(FMN binding)|go:"GO:0045121"(membrane raft)|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|interpro:IPR029039	refseq:NP_079331.3|interpro:IPR000008(C2 calcium-dependent membrane targeting)|go:"GO:0005777"(peroxisome)|refseq:NP_001274110.1|refseq:NP_877592.2|mint:Q8N5R6|interpro:IPR035892|interpro:IPR039889	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2021/11/30	rogid:cb04D8hoVh5fvWEd5oT6iDTL2X0559292	rogid:eEIn7pQyfdHWx8TeLJpYy0i/gww9606	intact-crc:2B4640DF9ABE2442|rigid:IRoMaPKSynRAVuLRVfQGYPuTB3o	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P38182	uniprotkb:O43379	intact:EBI-2684|uniprotkb:D6VPS5|ensemblfungi:YBL078C	intact:EBI-714790|uniprotkb:Q63HP9|uniprotkb:Q659D7|uniprotkb:Q8NBF7|uniprotkb:Q96AD9|intact:EBI-2563293|ensembl:ENSP00000270301	psi-mi:atg8_yeast(display_long)|uniprotkb:ATG8(gene name)|psi-mi:ATG8(display_short)|uniprotkb:APG8(gene name synonym)|uniprotkb:AUT7(gene name synonym)|uniprotkb:YBL078C(locus name)|uniprotkb:YBL0732(orf name)|uniprotkb:CVT5(gene name synonym)|uniprotkb:Autophagy-related ubiquitin-like modifier ATG8(gene name synonym)|uniprotkb:Cytoplasm to vacuole targeting protein 5(gene name synonym)	psi-mi:wdr62_human(display_long)|uniprotkb:WDR62(gene name)|psi-mi:WDR62(display_short)|uniprotkb:C19orf14(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549464|imex:IM-24995-2937	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000000174|refseq:NP_009475.1|dip:DIP-1197N|mint:P38182|ensemblfungi:YBL078C(gene)|ensemblfungi:YBL078C_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006914"(autophagy)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0008429"(phosphatidylethanolamine binding)|go:"GO:0016236"(macroautophagy)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0031386"(protein tag)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0033110"(Cvt vesicle membrane)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0034629"|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|go:"GO:0061025"(membrane fusion)|go:"GO:0061709"(reticulophagy)|go:"GO:0071211"(protein targeting to vacuole involved in autophagy)|go:"GO:0120095"(vacuole-isolation membrane contact site)|go:"GO:1905153"(regulation of membrane invagination)|interpro:IPR004241("Light chain 3 (LC3)")|interpro:IPR029071|rcsb pdb:2KQ7|rcsb pdb:2KWC|rcsb pdb:2LI5|rcsb pdb:2ZPN|rcsb pdb:3RUI|rcsb pdb:3VH3|rcsb pdb:3VH4|rcsb pdb:3VXW|rcsb pdb:5YEC|rcsb pdb:6AAG|rcsb pdb:6WY6|rcsb pdb:7BRN|reactome:R-SCE-1632852|reactome:R-SCE-8854214|reactome:R-SCE-8934903	go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007099"(centriole replication)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0022008"(neurogenesis)|go:"GO:0034451"(centriolar satellite)|interpro:IPR001680(WD40 repeat)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR024977|interpro:IPR036322|mint:O43379|go:"GO:0005813"(centrosome)|ensembl:ENSG00000075702(gene)|ensembl:ENST00000270301(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|refseq:NP_001077430.1|refseq:NP_775907.4|refseq:XP_016882154.1|dip:DIP-56792N	-	crc64:1246CEFF5A038819	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:UlmpBW3JgdYFHLkZCQeJeb7DpK4559292	rogid:bKUivd80luQPFZHsU9mDdwyGwi89606	intact-crc:83E9798513DE6590|rigid:Mf1TAEYS+GdwEh4qdc1A2+skDkQ	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P38182	uniprotkb:O60238	intact:EBI-2684|uniprotkb:D6VPS5|ensemblfungi:YBL078C	intact:EBI-849893|uniprotkb:Q5JW63|uniprotkb:Q8NF87|uniprotkb:B0AZS9|intact:EBI-28977676|ensembl:ENSP00000370003	psi-mi:atg8_yeast(display_long)|uniprotkb:ATG8(gene name)|psi-mi:ATG8(display_short)|uniprotkb:APG8(gene name synonym)|uniprotkb:AUT7(gene name synonym)|uniprotkb:YBL078C(locus name)|uniprotkb:YBL0732(orf name)|uniprotkb:CVT5(gene name synonym)|uniprotkb:Autophagy-related ubiquitin-like modifier ATG8(gene name synonym)|uniprotkb:Cytoplasm to vacuole targeting protein 5(gene name synonym)	psi-mi:bni3l_human(display_long)|uniprotkb:NIP3-like protein X(gene name synonym)|uniprotkb:BCL2/adenovirus E1B 19 kDa protein-interacting protein 3A(gene name synonym)|uniprotkb:Adenovirus E1B19K-binding protein B5(gene name synonym)|uniprotkb:BNIP3L(gene name)|psi-mi:BNIP3L(display_short)|uniprotkb:BNIP3A(gene name synonym)|uniprotkb:BNIP3H(gene name synonym)|uniprotkb:NIX(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549468|imex:IM-24995-2938	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000000174|refseq:NP_009475.1|dip:DIP-1197N|mint:P38182|ensemblfungi:YBL078C(gene)|ensemblfungi:YBL078C_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006914"(autophagy)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0008429"(phosphatidylethanolamine binding)|go:"GO:0016236"(macroautophagy)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0031386"(protein tag)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0033110"(Cvt vesicle membrane)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0034629"|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|go:"GO:0061025"(membrane fusion)|go:"GO:0061709"(reticulophagy)|go:"GO:0071211"(protein targeting to vacuole involved in autophagy)|go:"GO:0120095"(vacuole-isolation membrane contact site)|go:"GO:1905153"(regulation of membrane invagination)|interpro:IPR004241("Light chain 3 (LC3)")|interpro:IPR029071|rcsb pdb:2KQ7|rcsb pdb:2KWC|rcsb pdb:2LI5|rcsb pdb:2ZPN|rcsb pdb:3RUI|rcsb pdb:3VH3|rcsb pdb:3VH4|rcsb pdb:3VXW|rcsb pdb:5YEC|rcsb pdb:6AAG|rcsb pdb:6WY6|rcsb pdb:7BRN|reactome:R-SCE-1632852|reactome:R-SCE-8854214|reactome:R-SCE-8934903	refseq:NP_004322.1|ensembl:ENSP00000370003|ensembl:ENST00000518611|ensembl:ENSP00000429851|ensembl:ENST00000520409|ensembl:ENSP00000428597|ensembl:ENST00000523515|ensembl:ENSP00000429698|dip:DIP-35187N|refseq:NP_001317420.1|ensembl:ENSG00000104765(gene)|ensembl:ENST00000380629(transcript)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0010917"(negative regulation of mitochondrial membrane potential)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016607"(nuclear speck)|go:"GO:0031224"(intrinsic component of membrane)|go:"GO:0035694"(mitochondrial protein catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043067"(regulation of programmed cell death)|go:"GO:0051607"(defense response to virus)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0097345"(mitochondrial outer membrane permeabilization)|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1903214"(regulation of protein targeting to mitochondrion)|interpro:IPR010548(BNIP3)|mint:O60238|reactome:R-HSA-6803204	-	crc64:1246CEFF5A038819	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:UlmpBW3JgdYFHLkZCQeJeb7DpK4559292	rogid:GPDlK/z2VOVzJspIhN8XNFPSVMo9606	intact-crc:9D23C4A3EB6524D7|rigid:qQxn+uhb8vHnRhHxH9+ec9/R3nQ	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P14373	uniprotkb:P38203	intact:EBI-719493|uniprotkb:A2BE15|uniprotkb:Q5RJA8|uniprotkb:Q5ST26|uniprotkb:Q6LA73|uniprotkb:Q6NXR9|uniprotkb:Q9BZY6|uniprotkb:Q9UJL3|ensembl:ENSP00000383555|ensembl:ENSP00000392787|ensembl:ENSP00000405229|ensembl:ENSP00000414793|ensembl:ENSP00000366404	intact:EBI-180|ensemblfungi:YBL026W|uniprotkb:D6VPX4	psi-mi:tri27_human(display_long)|uniprotkb:TRIM27(gene name)|psi-mi:TRIM27(display_short)|uniprotkb:RNF76(gene name synonym)|uniprotkb:RFP(gene name synonym)|uniprotkb:Ret finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 27(gene name synonym)|uniprotkb:RING finger protein 76(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM27(gene name synonym)	psi-mi:lsm2_yeast(display_long)|uniprotkb:LSM2(gene name)|psi-mi:LSM2(display_short)|uniprotkb:Small nuclear ribonucleoprotein D homolog SNP3(gene name synonym)|uniprotkb:SMX5(gene name synonym)|uniprotkb:SNP3(gene name synonym)|uniprotkb:YBL0425(orf name)|uniprotkb:YBL026W(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549472|imex:IM-24995-2939	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006501.1|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0090281"(negative regulation of calcium ion import)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR020457|interpro:IPR035791|interpro:IPR043136|mint:P14373|reactome:R-HSA-3232142|reactome:R-HSA-9635465|reactome:R-HSA-8948751|ensembl:ENSG00000204713(gene)|ensembl:ENSG00000215641(gene)|ensembl:ENSG00000229006(gene)|ensembl:ENSG00000234495(gene)|ensembl:ENSG00000237071(gene)|ensembl:ENST00000377199(transcript)|ensembl:ENST00000400720(transcript)|ensembl:ENST00000431123(transcript)|ensembl:ENST00000435528(transcript)|ensembl:ENST00000437160(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001650"(fibrillar center)|go:"GO:0002820"(negative regulation of adaptive immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)	refseq:NP_009527.1|sgd:S000000122|go:"GO:0005688"(U6 snRNP)|go:"GO:0005730"(nucleolus)|go:"GO:0005732"("sno(s)RNA-containing ribonucleoprotein complex")|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0008033"(tRNA processing)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990726"(Lsm1-7-Pat1 complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR016654(U6 snRNA-associated Sm-like protein LSm2)|rcsb pdb:3JCM|rcsb pdb:4C8Q|rcsb pdb:4C92|rcsb pdb:4M75|rcsb pdb:4M77|ensemblfungi:YBL026W(gene)|ensemblfungi:YBL026W_mRNA(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|mint:P38203|dip:DIP-794N|rcsb pdb:4M78|rcsb pdb:4M7A|rcsb pdb:4M7D|rcsb pdb:4N0A|rcsb pdb:5GAN|rcsb pdb:5NRL|rcsb pdb:5VSU|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:6ASO|reactome:R-SCE-430039	-	-	crc64:C23856268CEE92E2	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:dsfH5OUghD8KSaTz1SFw9OYVTK49606	rogid:3E5c7Mzg433awFPmamamsKjtJmY559292	intact-crc:47C1A14B829AE8A6|rigid:hXyimIo/ILQQZTcsfdF11Q+LFPc	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P14373	uniprotkb:P38263	intact:EBI-719493|uniprotkb:A2BE15|uniprotkb:Q5RJA8|uniprotkb:Q5ST26|uniprotkb:Q6LA73|uniprotkb:Q6NXR9|uniprotkb:Q9BZY6|uniprotkb:Q9UJL3|ensembl:ENSP00000383555|ensembl:ENSP00000392787|ensembl:ENSP00000405229|ensembl:ENSP00000414793|ensembl:ENSP00000366404	intact:EBI-20304|uniprotkb:D6VQA4|ensemblfungi:YBR105C	psi-mi:tri27_human(display_long)|uniprotkb:TRIM27(gene name)|psi-mi:TRIM27(display_short)|uniprotkb:RNF76(gene name synonym)|uniprotkb:RFP(gene name synonym)|uniprotkb:Ret finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 27(gene name synonym)|uniprotkb:RING finger protein 76(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM27(gene name synonym)	psi-mi:gid4_yeast(display_long)|uniprotkb:VID24(gene name)|psi-mi:VID24(display_short)|uniprotkb:YBR105C(locus name)|uniprotkb:YBR0834(orf name)|uniprotkb:GID4(gene name synonym)|uniprotkb:Glucose-induced degradation protein 4(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549496|imex:IM-24995-2945	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006501.1|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0090281"(negative regulation of calcium ion import)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR020457|interpro:IPR035791|interpro:IPR043136|mint:P14373|reactome:R-HSA-3232142|reactome:R-HSA-9635465|reactome:R-HSA-8948751|ensembl:ENSG00000204713(gene)|ensembl:ENSG00000215641(gene)|ensembl:ENSG00000229006(gene)|ensembl:ENSG00000234495(gene)|ensembl:ENSG00000237071(gene)|ensembl:ENST00000377199(transcript)|ensembl:ENST00000400720(transcript)|ensembl:ENST00000431123(transcript)|ensembl:ENST00000435528(transcript)|ensembl:ENST00000437160(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001650"(fibrillar center)|go:"GO:0002820"(negative regulation of adaptive immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)	refseq:NP_009663.1|sgd:S000000309|ensemblfungi:YBR105C(gene)|ensemblfungi:YBR105C_mRNA(transcript)|go:"GO:0005773"(vacuole)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0007039"(protein catabolic process in the vacuole)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034657"(GID complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045721"(negative regulation of gluconeogenesis)|go:"GO:0071596"(ubiquitin-dependent protein catabolic process via the N-end rule pathway)|interpro:IPR018618|rcsb pdb:6SWY|dip:DIP-4502N|mint:P38263	-	-	crc64:FF020B239676E0B2	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:dsfH5OUghD8KSaTz1SFw9OYVTK49606	rogid:ag6caXMIP/qIv27yJtSEmlBoI7g559292	intact-crc:A9508B563CF6E543|rigid:Euv0GGsb1JA1Id2ofa27N81yVkI	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q08379	uniprotkb:P38263	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	intact:EBI-20304|uniprotkb:D6VQA4|ensemblfungi:YBR105C	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:gid4_yeast(display_long)|uniprotkb:VID24(gene name)|psi-mi:VID24(display_short)|uniprotkb:YBR105C(locus name)|uniprotkb:YBR0834(orf name)|uniprotkb:GID4(gene name synonym)|uniprotkb:Glucose-induced degradation protein 4(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549492|imex:IM-24995-2944	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N	refseq:NP_009663.1|sgd:S000000309|ensemblfungi:YBR105C(gene)|ensemblfungi:YBR105C_mRNA(transcript)|go:"GO:0005773"(vacuole)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0007039"(protein catabolic process in the vacuole)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034657"(GID complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045721"(negative regulation of gluconeogenesis)|go:"GO:0071596"(ubiquitin-dependent protein catabolic process via the N-end rule pathway)|interpro:IPR018618|rcsb pdb:6SWY|dip:DIP-4502N|mint:P38263	-	-	crc64:FF020B239676E0B2	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2017/05/26	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	rogid:ag6caXMIP/qIv27yJtSEmlBoI7g559292	intact-crc:FFC015CFA67A236F|rigid:tulP4I+Hi4CulghhzjhObGzAJfk	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O95273	uniprotkb:P38260	intact:EBI-748961|uniprotkb:A8K3Q0|uniprotkb:A8K3U2|uniprotkb:Q6ZQN9|uniprotkb:Q7Z519|uniprotkb:Q8NBS7|uniprotkb:Q8NBY2|uniprotkb:Q9NS19|uniprotkb:Q9NYH3|uniprotkb:Q9UHX9|ensembl:ENSP00000300213	intact:EBI-21563|uniprotkb:D6VQA0|ensemblfungi:YBR101C	psi-mi:ccdb1_human(display_long)|uniprotkb:Grap2 and cyclin-D-interacting protein(gene name synonym)|uniprotkb:Human homolog of Maid(gene name synonym)|uniprotkb:CCNDBP1(gene name)|psi-mi:CCNDBP1(display_short)|uniprotkb:DIP1(gene name synonym)|uniprotkb:GCIP(gene name synonym)|uniprotkb:HHM(gene name synonym)	psi-mi:fes1_yeast(display_long)|uniprotkb:YBR101C(locus name)|uniprotkb:YBR0830(orf name)|uniprotkb:Factor exchange for SSA1 protein 1(gene name synonym)|uniprotkb:FES1(gene name)|psi-mi:FES1(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549480|imex:IM-24995-2941	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_036274.3|ensembl:ENSG00000166946(gene)|ensembl:ENST00000300213(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0016604"(nuclear body)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR026907|mint:O95273|rcsb pdb:3AY5	sgd:S000000305|refseq:NP_009659.3|mint:P38260|dip:DIP-4918N|ensemblfungi:YBR101C(gene)|ensemblfungi:YBR101C_mRNA(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006417"(regulation of translation)|go:"GO:0071629"(cytoplasm protein quality control by the ubiquitin-proteasome system)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013918(Nucleotide exchange factor Fes1)|interpro:IPR016024(Armadillo-type fold)	-	-	crc64:4A50D069625BA500	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:Vi9aoFc+Mov6P3X6KGmsTxXqxvM9606	rogid:swXhGbIfsVTGs+eOqqViPwySpI0559292	intact-crc:E9583E533668772B|rigid:oUDMwT/PEowBr+fIUoVzUYlKGIY	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P38260	uniprotkb:P11142	intact:EBI-21563|uniprotkb:D6VQA0|ensemblfungi:YBR101C	intact:EBI-351896|uniprotkb:Q9H3R6|ensembl:ENSP00000227378|ensembl:ENSP00000432083|ensembl:ENSP00000437125	psi-mi:fes1_yeast(display_long)|uniprotkb:YBR101C(locus name)|uniprotkb:YBR0830(orf name)|uniprotkb:Factor exchange for SSA1 protein 1(gene name synonym)|uniprotkb:FES1(gene name)|psi-mi:FES1(display_short)	psi-mi:hsp7c_human(display_long)|uniprotkb:HSPA8(gene name)|psi-mi:HSPA8(display_short)|uniprotkb:HSC70(gene name synonym)|uniprotkb:HSP73(gene name synonym)|uniprotkb:HSPA10(gene name synonym)|uniprotkb:Heat shock 70 kDa protein 8(gene name synonym)|uniprotkb:Lipopolysaccharide-associated protein 1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549484|imex:IM-24995-2942	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000000305|refseq:NP_009659.3|mint:P38260|dip:DIP-4918N|ensemblfungi:YBR101C(gene)|ensemblfungi:YBR101C_mRNA(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006417"(regulation of translation)|go:"GO:0071629"(cytoplasm protein quality control by the ubiquitin-proteasome system)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013918(Nucleotide exchange factor Fes1)|interpro:IPR016024(Armadillo-type fold)	refseq:NP_006588.1|refseq:NP_694881.1|refseq:XP_011541100.1|ensembl:ENSG00000109971(gene)|ensembl:ENST00000227378(transcript)|ensembl:ENST00000532636(transcript)|ensembl:ENST00000534624(transcript)|go:"GO:0000974"(Prp19 complex)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006397"(mRNA processing)|go:"GO:0006457"(protein folding)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008380"(RNA splicing)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030425"(dendrite)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042026"(protein refolding)|go:"GO:0042470"(melanosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0043195"(terminal bouton)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044829"(positive regulation by host of viral genome replication)|go:"GO:0045296"(cadherin binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0055131"(C3HC4-type RING finger domain binding)|go:"GO:0061024"(membrane organization)|go:"GO:0061202"(clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane)|go:"GO:0061635"(regulation of protein complex stability)|go:"GO:0061684"(chaperone-mediated autophagy)|go:"GO:0061738"(late endosomal microautophagy)|go:"GO:0061740"(protein targeting to lysosome involved in chaperone-mediated autophagy)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0098575"(lumenal side of lysosomal membrane)|go:"GO:0098684"(photoreceptor ribbon synapse)|go:"GO:0098690"(glycinergic synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099175"(regulation of postsynapse organization)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099634"(postsynaptic specialization membrane)|go:"GO:0101031"(chaperone complex)|go:"GO:0140545"(protein disaggregase activity)|go:"GO:0140597"(protein carrier chaperone)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902904"(negative regulation of supramolecular fiber organization)|go:"GO:1904589"(regulation of protein import)|go:"GO:1904764"(chaperone-mediated autophagy translocation complex disassembly)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1990832"(slow axonal transport)|go:"GO:1990833"(clathrin-uncoating ATPase activity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|mint:P11142|rcsb pdb:3AGY|rcsb pdb:3AGZ|rcsb pdb:3ESK|rcsb pdb:3FZF|rcsb pdb:3FZH|rcsb pdb:3FZK|rcsb pdb:3FZL|rcsb pdb:3FZM|rcsb pdb:3LDQ|rcsb pdb:3M3Z|rcsb pdb:4H5N|rcsb pdb:4H5R|rcsb pdb:4H5T|rcsb pdb:4H5V|rcsb pdb:4H5W|rcsb pdb:4HWI|rcsb pdb:4KBQ|rcsb pdb:5AQF|rcsb pdb:5AQG|rcsb pdb:5AQH|rcsb pdb:5AQI|rcsb pdb:5AQJ|rcsb pdb:5AQK|rcsb pdb:5AQL|rcsb pdb:5AQM|rcsb pdb:5AQN|rcsb pdb:5AQO|rcsb pdb:5AQP|rcsb pdb:5AQQ|rcsb pdb:5AQR|rcsb pdb:5AQS|rcsb pdb:5AQT|rcsb pdb:5AQU|rcsb pdb:5AQV|rcsb pdb:6B1I|rcsb pdb:6B1M|rcsb pdb:6B1N|rcsb pdb:6ZYJ|reactome:R-HSA-3371453|reactome:R-HSA-3371497|reactome:R-HSA-3371568|reactome:R-HSA-3371571|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-447041|reactome:R-HSA-450408|reactome:R-HSA-6785807|reactome:R-HSA-6798695|reactome:R-HSA-72163|reactome:R-HSA-8856828|reactome:R-HSA-8876725|reactome:R-HSA-888590|reactome:R-HSA-9613354|reactome:R-HSA-9613829|reactome:R-HSA-9615710|dip:DIP-32874N	-	crc64:4A50D069625BA500	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:swXhGbIfsVTGs+eOqqViPwySpI0559292	rogid:0I+wYut3naJRzzgmMSax/1mZZwA9606	intact-crc:D8B8D5C1C1FA3966|rigid:wjVULKBxWaRB64mV9VWXcOKdgDU	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q08379	uniprotkb:P38261	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	intact:EBI-21567|uniprotkb:D6VQA1|ensemblfungi:YBR102C	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:exo84_yeast(display_long)|uniprotkb:YBR102C(locus name)|uniprotkb:YBR0831(orf name)|uniprotkb:Exocyst complex protein of 84 kDa(gene name synonym)|uniprotkb:EXO84(gene name)|psi-mi:EXO84(display_short)|uniprotkb:USA3(gene name synonym)|uniprotkb:U1 SNP1-associating protein 3(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549488|imex:IM-24995-2943	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N	refseq:NP_009660.1|sgd:S000000306|mint:P38261|dip:DIP-2732N|ensemblfungi:YBR102C(gene)|ensemblfungi:YBR102C_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0000145"(exocyst)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0001927"(exocyst assembly)|go:"GO:0005628"(prospore membrane)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0008104"(protein localization)|go:"GO:0015031"(protein transport)|go:"GO:0030133"(transport vesicle)|go:"GO:0043332"(mating projection tip)|go:"GO:0051601"(exocyst localization)|go:"GO:0090522"(vesicle tethering involved in exocytosis)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR032403|interpro:IPR033961|interpro:IPR042560|interpro:IPR042561|rcsb pdb:2D2S|rcsb pdb:5YFP|rcsb pdb:6VKL|reactome:R-SCE-264876	-	-	crc64:1BCDE834466C3536	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2017/05/26	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	rogid:tJ29//zd8m0QGJu94oH597pBVTg559292	intact-crc:8C0B87D249EBB446|rigid:CwIf3wQ9preYNggEHdldYdCDy/w	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O00635	uniprotkb:P38340	intact:EBI-2130415|uniprotkb:B2R862|ensembl:ENSP00000349596	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:tri38_human(display_long)|uniprotkb:TRIM38(gene name)|psi-mi:TRIM38(display_short)|uniprotkb:RNF15(gene name synonym)|uniprotkb:RORET(gene name synonym)|uniprotkb:RING finger protein 15(gene name synonym)|uniprotkb:Zinc finger protein RoRet(gene name synonym)|uniprotkb:Tripartite motif-containing protein 38(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM38(gene name synonym)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549512|imex:IM-24995-2949	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006346.1|refseq:XP_005248856.1|refseq:XP_005248857.1|ensembl:ENSG00000112343(gene)|ensembl:ENST00000357085(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046598"(positive regulation of viral entry into host cell)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR035790|interpro:IPR043136|reactome:R-HSA-877300	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F	-	-	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Zh4X/6v/qKZlDkMV6hhn7OsvPnQ9606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:9199D008C7033BFA|rigid:PSSGJVXhFQXVtirX3AU6PNf5XwQ	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P38265	uniprotkb:P14136	intact:EBI-21579|uniprotkb:D6VQA6|ensemblfungi:YBR107C	intact:EBI-744302|uniprotkb:Q53H98|uniprotkb:Q5D055|uniprotkb:Q6ZQS3|uniprotkb:Q7Z5J6|uniprotkb:Q7Z5J7|uniprotkb:Q96KS4|uniprotkb:Q96P18|uniprotkb:Q9UFD0|uniprotkb:B2RD44|uniprotkb:D3DX59|intact:EBI-3909365|uniprotkb:E9PAX3|ensembl:ENSP00000466598|uniprotkb:A7REI1	psi-mi:cenpl_yeast(display_long)|uniprotkb:YBR107C(locus name)|uniprotkb:YBR0836(orf name)|uniprotkb:Increased minichromosome loss protein 3(gene name synonym)|uniprotkb:Minichromosome maintenance protein 19(gene name synonym)|uniprotkb:IML3(gene name)|psi-mi:IML3(display_short)|uniprotkb:MCM19(gene name synonym)|uniprotkb:CENP-L homolog(gene name synonym)|uniprotkb:Constitutive centromere-associated network protein IML3(gene name synonym)	psi-mi:gfap_human(display_long)|uniprotkb:GFAP(gene name)|psi-mi:GFAP(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549500|imex:IM-24995-2946	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000000311|refseq:NP_009665.3|mint:P38265|dip:DIP-5360N|ensemblfungi:YBR107C(gene)|ensemblfungi:YBR107C_mRNA(transcript)|go:"GO:0000940"(outer kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0030437"(ascospore formation)|go:"GO:0034087"(establishment of mitotic sister chromatid cohesion)|go:"GO:0034089"(establishment of meiotic sister chromatid cohesion)|go:"GO:0034090"(maintenance of meiotic sister chromatid cohesion)|go:"GO:0045144"(meiotic sister chromatid segregation)|go:"GO:0051301"(cell division)|go:"GO:0071459"(protein localization to chromosome, centromeric region)|rcsb pdb:4IT3|rcsb pdb:4JE3|rcsb pdb:4KR1|rcsb pdb:6NUW|rcsb pdb:6QLD|rcsb pdb:6QLE|rcsb pdb:6QLF	refseq:NP_001124491.1|refseq:NP_001229305.1|refseq:NP_002046.1|ensembl:ENSG00000131095(gene)|ensembl:ENST00000588735(transcript)|go:"GO:0005178"(integrin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0009611"(response to wounding)|go:"GO:0010467"(gene expression)|go:"GO:0010625"(positive regulation of Schwann cell proliferation)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0014002"(astrocyte development)|go:"GO:0019900"(kinase binding)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0031102"(neuron projection regeneration)|go:"GO:0042802"(identical protein binding)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0044297"(cell body)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0051580"(regulation of neurotransmitter uptake)|go:"GO:0060020"(Bergmann glial cell differentiation)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0070779"(D-aspartate import across plasma membrane)|go:"GO:0097450"(astrocyte end-foot)|go:"GO:0098574"(cytoplasmic side of lysosomal membrane)|go:"GO:1904714"(regulation of chaperone-mediated autophagy)|interpro:IPR006821(Intermediate filament, DNA-binding region)|interpro:IPR018039|interpro:IPR027701|interpro:IPR039008|mint:P14136|rcsb pdb:6A9P|reactome:R-HSA-1251985|reactome:R-HSA-9613829	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:Wq132ybN9X9ZoP+Z9KcTTvkz2t4559292	rogid:Pz4JW0WjMjBYILTDSX9jUmMqWhg9606	intact-crc:EC8AA6508AC77603|rigid:hWeq1Mm67dM5sUZLU4tMzDOgmUA	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O43617	uniprotkb:P38334	intact:EBI-743566|uniprotkb:B2RDN2|uniprotkb:D3DPS2|uniprotkb:A6NDN0|ensembl:ENSP00000362261	intact:EBI-19468|uniprotkb:D6VQQ0|ensemblfungi:YBR254C	psi-mi:tppc3_human(display_long)|uniprotkb:BET3 homolog(gene name synonym)|uniprotkb:TRAPPC3(gene name)|psi-mi:TRAPPC3(display_short)|uniprotkb:BET3(gene name synonym)|uniprotkb:CDABP0066(orf name)	psi-mi:trs20_yeast(display_long)|uniprotkb:TRS20(gene name)|psi-mi:TRS20(display_short)|uniprotkb:YBR254C(locus name)|uniprotkb:YBR1722(orf name)|uniprotkb:Transport protein particle 20 kDa subunit(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549504|imex:IM-24995-2947	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055223.1|refseq:NP_001257823.1|refseq:NP_001257824.1|refseq:NP_001257825.1|refseq:NP_001257826.1|ensembl:ENSG00000054116(gene)|ensembl:ENST00000373166(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0030008"(TRAPP complex)|go:"GO:0033106"(cis-Golgi network membrane)|interpro:IPR007194("Transport protein particle (TRAPP) component, Bet3")|interpro:IPR016721(TRAPP I complex, Bet3)|interpro:IPR024096|mint:O43617|rcsb pdb:1SZ7|rcsb pdb:2C0J|rcsb pdb:2CFH|rcsb pdb:3KXC|reactome:R-HSA-204005|reactome:R-HSA-8876198|dip:DIP-47627N	refseq:NP_009813.1|sgd:S000000458|ensemblfungi:YBR254C(gene)|ensemblfungi:YBR254C_mRNA(transcript)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006914"(autophagy)|go:"GO:0030008"(TRAPP complex)|go:"GO:0034622"|go:"GO:1990070"(TRAPPI protein complex)|go:"GO:1990071"(TRAPPII protein complex)|go:"GO:1990072"(TRAPPIII protein complex)|interpro:IPR006722(Sedlin)|interpro:IPR011012(Longin-like)|rcsb pdb:7KMT|reactome:R-SCE-204005|reactome:R-SCE-8876198|dip:DIP-1711N|mint:P38334	-	-	crc64:82285CAEAC2735D9	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:YEQWfs0KIBIDkvJ+2Xtz8afsDCc9606	rogid:RaZlF+nwUS/H7Sprxgo1jQ38V+8559292	intact-crc:99BA589D7BA83AEE|rigid:UVDmTrFMJBfUf4/fBI8TwZplmlE	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O14641	uniprotkb:P38339	intact:EBI-740850|ensembl:ENSP00000005340|uniprotkb:Q53XM0|uniprotkb:D3DTN3	intact:EBI-15065|uniprotkb:D6VQQ7|ensemblfungi:YBR260C	psi-mi:dvl2_human(display_long)|uniprotkb:DSH homolog 2(gene name synonym)|uniprotkb:DVL2(gene name)|psi-mi:DVL2(display_short)	psi-mi:rgd1_yeast(display_long)|uniprotkb:RGD1(gene name)|psi-mi:RGD1(display_short)|uniprotkb:YBR260C(locus name)|uniprotkb:YBR1728(orf name)|uniprotkb:Related GAP domain protein 1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549508|imex:IM-24995-2948	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004413.1|ensembl:ENSG00000004975(gene)|ensembl:ENST00000005340(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005109"(frizzled binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0007507"(heart development)|go:"GO:0016235"(aggresome)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044340"(canonical Wnt signaling pathway involved in regulation of cell proliferation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0150012"(positive regulation of neuron projection arborization)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008341(Dishevelled-2 region)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:O14641|rcsb pdb:2REY|rcsb pdb:3CBX|rcsb pdb:3CBY|rcsb pdb:3CBZ|rcsb pdb:3CC0|rcsb pdb:4WIP|rcsb pdb:5LNP|rcsb pdb:5SUY|rcsb pdb:5SUZ|rcsb pdb:6IW3|rcsb pdb:6JCK|reactome:R-HSA-201681|reactome:R-HSA-201688|reactome:R-HSA-2028269|reactome:R-HSA-4086400|reactome:R-HSA-4608870|reactome:R-HSA-4641258|reactome:R-HSA-4641262|reactome:R-HSA-5099900|reactome:R-HSA-5368598|reactome:R-HSA-5663220|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9673324|ensembl:ENSP00000005340|dip:DIP-34433N	refseq:NP_009819.1|sgd:S000000464|ensemblfungi:YBR260C(gene)|ensemblfungi:YBR260C_mRNA(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005628"(prospore membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005933"(cellular bud)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007165"(signal transduction)|go:"GO:0010314"(phosphatidylinositol-5-phosphate binding)|go:"GO:0010447"(response to acidic pH)|go:"GO:0030479"(actin cortical patch)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043332"(mating projection tip)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|interpro:IPR000198(RhoGAP)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR027267|interpro:IPR031160|rcsb pdb:4WPC|rcsb pdb:5MY3|reactome:R-SCE-6798695|reactome:R-SCE-8980692|reactome:R-SCE-9013148|reactome:R-SCE-9013405|reactome:R-SCE-9013423|reactome:R-SCE-9035034|dip:DIP-4950N|mint:P38339	-	-	crc64:711D9CC717E9111D	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:2Vdc8oRnT4Mz/j+EXQXrL3AszOc9606	rogid:xHHGufxy5DvB8ngwbICIkYD3DA8559292	intact-crc:FBE844E9820F9297|rigid:NC2obhGm8+/XWATnLm6RDtrAfj8	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O60232	uniprotkb:P38340	intact:EBI-741415|ensembl:ENSP00000312318	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:znrd2_human(display_long)|uniprotkb:ZNRD2(gene name)|psi-mi:ZNRD2(display_short)|uniprotkb:Autoantigen p27(gene name synonym)|uniprotkb:SSSCA1(gene name synonym)|uniprotkb:Sjoegren syndrome/scleroderma autoantigen 1(gene name synonym)|uniprotkb:Zinc ribbon domain-containing protein 2(gene name synonym)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549532|imex:IM-24995-2954	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006387.1|ensembl:ENSG00000173465(gene)|ensembl:ENST00000309328(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0051301"(cell division)|interpro:IPR009563(Sjogrens syndrome scleroderma autoantigen 1)|rcsb pdb:6HCZ	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F	-	-	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:Uou80pZneoL39/0YYzb1TAbiB2I9606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:D140C9569DCCC7C5|rigid:r8e1XvMTUwwFv0utOolzotby7J8	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P38340	uniprotkb:P23511-2	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-11061759|ensembl:ENSP00000229418	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:p23511-2(display_long)|uniprotkb:NFYA(gene name)|psi-mi:NFYA(display_short)|uniprotkb:CAAT box DNA-binding protein subunit A(gene name synonym)|uniprotkb:Nuclear transcription factor Y subunit A(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549528|imex:IM-24995-2953	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F	intact:EBI-389739(isoform-parent)|ensembl:ENSG00000001167(gene)|ensembl:ENST00000353205(transcript)|uniprotkb:P23511-2(isoform-parent)	-	crc64:66699F37B0013088	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:9IOUoaGszX6kd9hzrCj6BBkgJ+09606	intact-crc:B83E3079F4772EB3|rigid:G3HyeGy+Y4dllNBePDME7Qpu6I8	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P38159	uniprotkb:P38340	intact:EBI-743526|ensembl:ENSP00000359645|uniprotkb:Q5JQ67|uniprotkb:Q969R3|uniprotkb:D3DWH0|uniprotkb:E9PG86|uniprotkb:Q8N8Y7|uniprotkb:B4E3U4	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:rbmx_human(display_long)|uniprotkb:Glycoprotein p43(gene name synonym)|uniprotkb:RBMX(gene name)|psi-mi:RBMX(display_short)|uniprotkb:HNRPG(gene name synonym)|uniprotkb:RBMXP1(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein G(gene name synonym)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549516|imex:IM-24995-2950	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000147274(gene)|ensembl:ENST00000320676(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000791"(euchromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0044530"(supraspliceosomal complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0006509"(membrane protein ectodomain proteolysis)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012604(RBM1CTR)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|mint:P38159|rcsb pdb:2MB0|rcsb pdb:2MKS|reactome:R-HSA-72163|reactome:R-HSA-72203|reactome:R-HSA-9013418|reactome:R-HSA-9013422|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273|refseq:NP_002130.2|refseq:NP_001158275.1|dip:DIP-34447N	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F	-	-	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:ocCkdy9PxjeVLUQf0tMVCEhFfO89606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:4BA6424E75C6332E|rigid:Lr3MO6Jzc9pvQFInXgb84MSkeJ8	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P38340	uniprotkb:O43791	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-743549|uniprotkb:Q53HJ1|uniprotkb:B2R6S3|uniprotkb:D3DTW7|ensembl:ENSP00000240327|ensembl:ENSP00000377001|ensembl:ENSP00000420908|ensembl:ENSP00000424119|ensembl:ENSP00000425905|ensembl:ENSP00000426986|ensembl:ENSP00000499562	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:spop_human(display_long)|uniprotkb:HIB homolog 1(gene name synonym)|uniprotkb:Roadkill homolog 1(gene name synonym)|uniprotkb:SPOP(gene name)|psi-mi:SPOP(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549520|imex:IM-24995-2951	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F	refseq:NP_001007227.1|refseq:NP_001007228.1|refseq:NP_001007229.1|refseq:NP_001007230.1|refseq:NP_001007231.1|refseq:NP_003554.1|refseq:XP_005257780.1|refseq:XP_005257781.1|ensembl:ENSG00000121067(gene)|ensembl:ENST00000347630(transcript)|ensembl:ENST00000393328(transcript)|ensembl:ENST00000503676(transcript)|ensembl:ENST00000504102(transcript)|ensembl:ENST00000509079(transcript)|ensembl:ENST00000514121(transcript)|ensembl:ENST00000665825(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0016607"(nuclear speck)|go:"GO:0030162"(regulation of proteolysis)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR034089|mint:O43791|rcsb pdb:2CR2|rcsb pdb:3HQH|rcsb pdb:3HQI|rcsb pdb:3HQL|rcsb pdb:3HQM|rcsb pdb:3HSV|rcsb pdb:3HTM|rcsb pdb:3HU6|rcsb pdb:3IVB|rcsb pdb:3IVQ|rcsb pdb:3IVV|rcsb pdb:4EOZ|rcsb pdb:4HS2|rcsb pdb:4J8Z|rcsb pdb:4O1V|rcsb pdb:6F8F|rcsb pdb:6F8G|rcsb pdb:6I41|rcsb pdb:6I5P|rcsb pdb:6I68|rcsb pdb:6I7A|rcsb pdb:7D3D|rcsb pdb:7LIN|rcsb pdb:7LIO|rcsb pdb:7LIP|rcsb pdb:7LIQ|reactome:R-HSA-5632684|go:"GO:0005634"(nucleus)|refseq:XP_016880693.1|dip:DIP-50517N	-	crc64:66699F37B0013088	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:PC9ofpvk14xwTnnqT590/YRnx/49606	intact-crc:0A590C6E51D4FC4B|rigid:t/pDXBo/dfZ4YElZ7GMLcsDBsrA	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O60547	uniprotkb:P38340	intact:EBI-746373|uniprotkb:O75357|uniprotkb:Q5T954|uniprotkb:Q6FH09|uniprotkb:Q9UGZ3|uniprotkb:Q9UJK9|ensembl:ENSP00000370194|intact:EBI-10968896|uniprotkb:E9PI88	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:gmds_human(display_long)|uniprotkb:GDP-D-mannose dehydratase(gene name synonym)|uniprotkb:GMDS(gene name)|psi-mi:GMDS(display_short)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549524|imex:IM-24995-2952	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001491.1|ensembl:ENSG00000112699(gene)|ensembl:ENST00000380815(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0008446"(GDP-mannose 4,6-dehydratase activity)|go:"GO:0019673"(GDP-mannose metabolic process)|go:"GO:0042351"('de novo' GDP-L-fucose biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070401"(NADP+ binding)|interpro:IPR006368(GDP-mannose 4,6-dehydratase)|interpro:IPR016040("NAD(P)-binding")|interpro:IPR036291|rcsb pdb:1T2A|rcsb pdb:5IN4|rcsb pdb:5IN5|rcsb pdb:6GPJ|rcsb pdb:6GPK|rcsb pdb:6GPL|rcsb pdb:6Q94|reactome:R-HSA-6787639|refseq:NP_001240775.1	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F	-	-	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:phGw3/m75gYQcBlRP3OXK4mQvhM9606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:976DC6A7E7096233|rigid:PrxLMY8mTgPT6dYfmKllhPebQmA	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P07195	uniprotkb:P38340	intact:EBI-358748|ensembl:ENSP00000229319|ensembl:ENSP00000379386	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:ldhb_human(display_long)|uniprotkb:LDHB(gene name)|psi-mi:LDHB(display_short)|uniprotkb:LDH heart subunit(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-46(gene name synonym)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549548|imex:IM-24995-2958	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001167568.1|refseq:NP_002291.1|refseq:NP_001302466.1|ensembl:ENSG00000111716(gene)|ensembl:ENST00000350669(transcript)|ensembl:ENST00000396076(transcript)|go:"GO:0004459"(L-lactate dehydrogenase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0019752"(carboxylic acid metabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0045121"(membrane raft)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001236(Lactate/malate dehydrogenase)|interpro:IPR001557(L-lactate/malate dehydrogenase)|interpro:IPR011304(L-lactate dehydrogenase)|interpro:IPR015955(Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal)|interpro:IPR018177|interpro:IPR022383|interpro:IPR036291|mint:P07195|rcsb pdb:1I0Z|rcsb pdb:1T2F|reactome:R-HSA-70268	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F	-	-	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:umdj6fjSO7+4SM9Hrl1/K2EiKls9606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:24E2DF5E96255E12|rigid:u8nJ3fWsXWTbmmVX+FV2vOEmMDQ	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O96006	uniprotkb:P38340	intact:EBI-740037|uniprotkb:Q96BY4|ensembl:ENSP00000370616|ensembl:ENSP00000370620|ensembl:ENSP00000370621|ensembl:ENSP00000498725	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:zbed1_human(display_long)|uniprotkb:ZBED1(gene name)|psi-mi:ZBED1(display_short)|uniprotkb:ALTE(gene name synonym)|uniprotkb:DREF(gene name synonym)|uniprotkb:KIAA0785(gene name synonym)|uniprotkb:TRAMP(gene name synonym)|uniprotkb:dREF homolog(gene name synonym)|uniprotkb:Putative Ac-like transposable element(gene name synonym)|uniprotkb:DNA replication-related element-binding factor(gene name synonym)|uniprotkb:Zinc finger BED domain-containing protein 1(gene name synonym)|uniprotkb:hDREF(gene name synonym)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549536|imex:IM-24995-2955	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164606.1|refseq:NP_001164607.1|refseq:NP_004720.1|ensembl:ENSG00000214717(gene)|ensembl:ENST00000381218(transcript)|ensembl:ENST00000381222(transcript)|ensembl:ENST00000381223(transcript)|ensembl:ENST00000652001(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0031965"(nuclear membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044828"(negative regulation by host of viral genome replication)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0061665"(SUMO ligase activity)|go:"GO:1990466"(protein autosumoylation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003656(Zinc finger, BED-type predicted)|interpro:IPR008906(HAT dimerisation)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR036236|mint:O96006|rcsb pdb:2CT5|reactome:R-HSA-4551638|go:"GO:0005813"(centrosome)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016605"(PML body)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F	-	-	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:jl97ZV2Kz5YAmQKktWt/wk7OkRw9606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:C3DDB33670C5CCB9|rigid:OsutfvhFYaGz8t3mj3RghBXI6Xw	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P38340	uniprotkb:P20591	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-929476|uniprotkb:D3DSI8|uniprotkb:B2RDA5|uniprotkb:B3KU10|uniprotkb:C9IYV7|uniprotkb:C9J8D6|uniprotkb:C9JN19|uniprotkb:C9JN88|uniprotkb:C9JUL1|uniprotkb:C9JZS6|uniprotkb:Q86YP5|uniprotkb:Q96CI3|ensembl:ENSP00000381599|ensembl:ENSP00000381601|ensembl:ENSP00000392151|ensembl:ENSP00000402215|ensembl:ENSP00000408498|ensembl:ENSP00000410523|ensembl:ENSP00000505029|ensembl:ENSP00000505047|ensembl:ENSP00000505051|ensembl:ENSP00000505189|ensembl:ENSP00000505457|ensembl:ENSP00000505489|ensembl:ENSP00000505630|ensembl:ENSP00000505657|ensembl:ENSP00000505669|ensembl:ENSP00000505781|ensembl:ENSP00000505874|ensembl:ENSP00000506047|ensembl:ENSP00000506062|ensembl:ENSP00000506183|ensembl:ENSP00000506199|ensembl:ENSP00000506220|ensembl:ENSP00000506270|ensembl:ENSP00000506348|ensembl:ENSP00000506372|ensembl:ENSP00000506395|ensembl:ENSP00000506481|ensembl:ENSP00000506512|ensembl:ENSP00000506690|ensembl:ENSP00000506712	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:mx1_human(display_long)|uniprotkb:MX1(gene name)|psi-mi:MX1(display_short)|uniprotkb:Myxovirus resistance protein 1(gene name synonym)|uniprotkb:Interferon-regulated resistance GTP-binding protein MxA(gene name synonym)|uniprotkb:Interferon-induced protein p78(gene name synonym)|uniprotkb:Myxoma resistance protein 1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549540|imex:IM-24995-2956	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F	refseq:NP_001269849.1|refseq:NP_001138397.1|refseq:NP_001171517.1|refseq:NP_002453.2|refseq:XP_011527870.1|refseq:XP_005261037.1|refseq:XP_005261038.1|refseq:XP_005261039.1|refseq:XP_005261035.1|refseq:XP_005261036.1|refseq:XP_016883838.1|refseq:XP_016883839.1|dip:DIP-35694N|ensembl:ENSG00000157601(gene)|ensembl:ENST00000398598(transcript)|ensembl:ENST00000398600(transcript)|ensembl:ENST00000413778(transcript)|ensembl:ENST00000417963(transcript)|ensembl:ENST00000419044(transcript)|ensembl:ENST00000455164(transcript)|ensembl:ENST00000679445(transcript)|ensembl:ENST00000679464(transcript)|ensembl:ENST00000679543(transcript)|ensembl:ENST00000679626(transcript)|ensembl:ENST00000679705(transcript)|ensembl:ENST00000679911(transcript)|ensembl:ENST00000680176(transcript)|ensembl:ENST00000680182(transcript)|ensembl:ENST00000680347(transcript)|ensembl:ENST00000680364(transcript)|ensembl:ENST00000680536(transcript)|ensembl:ENST00000680629(transcript)|ensembl:ENST00000680760(transcript)|ensembl:ENST00000680776(transcript)|ensembl:ENST00000681039(transcript)|ensembl:ENST00000681191(transcript)|ensembl:ENST00000681266(transcript)|ensembl:ENST00000681415(transcript)|ensembl:ENST00000681607(transcript)|ensembl:ENST00000681671(transcript)|ensembl:ENST00000681849(transcript)|ensembl:ENST00000681857(transcript)|ensembl:ENST00000681867(transcript)|ensembl:ENST00000681896(transcript)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0003374"(dynamin family protein polymerization involved in mitochondrial fission)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0006952"(defense response)|go:"GO:0007165"(signal transduction)|go:"GO:0008017"(microtubule binding)|go:"GO:0009615"(response to virus)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016185"(synaptic vesicle budding from presynaptic endocytic zone membrane)|go:"GO:0030424"(axon)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031623"(receptor internalization)|go:"GO:0031965"(nuclear membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0034340"(response to type I interferon)|go:"GO:0042802"(identical protein binding)|go:"GO:0044327"(dendritic spine head)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0051607"(defense response to virus)|go:"GO:0061025"(membrane fusion)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:0098793"(presynapse)|go:"GO:0098844"(postsynaptic endocytic zone membrane)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:0140374"(antiviral innate immune response)|interpro:IPR000375(Dynamin central region)|interpro:IPR001401(Dynamin, GTPase region)|interpro:IPR003130(Dynamin GTPase effector)|interpro:IPR019762|interpro:IPR020850|interpro:IPR022812|interpro:IPR027417|interpro:IPR030381|mint:P20591|rcsb pdb:3LJB|rcsb pdb:3SZR|rcsb pdb:3ZYS|rcsb pdb:4P4S|rcsb pdb:4P4T|rcsb pdb:4P4U|rcsb pdb:5GTM|reactome:R-HSA-1169408|reactome:R-HSA-909733	-	crc64:66699F37B0013088	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:9rO7Zyl6v0Kq3xw6MKbVefk1hCA9606	intact-crc:395E85091D1AA8F0|rigid:2isHB41HHZLGGKSn1+EQx02KZHg	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:A0A0R4J2E4	uniprotkb:P38340	intact:EBI-11525602|ensembl:ENSP00000324292	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:a0a0r4j2e4_human(display_long)|uniprotkb:FBF1(gene name)|psi-mi:FBF1(display_short)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549544|imex:IM-24995-2957	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000188878(gene)|ensembl:ENST00000319129(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0060271"(cilium assembly)|go:"GO:0090162"(establishment of epithelial cell polarity)|go:"GO:0097539"(ciliary transition fiber)|interpro:IPR033561	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F	-	-	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/03/16	rogid:N4h8foiP1+HSYZRE7i66zhtqKlQ9606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:D3D2C2492B006431|rigid:V5Ib2iPlTNrAWfrrK9eBf406bCo	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P38340	uniprotkb:O95045-2	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-11528386|ensembl:ENSP00000474090	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:o95045-2(display_long)|uniprotkb:UPP2(gene name)|psi-mi:UPP2(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549564|imex:IM-24995-2962	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F	intact:EBI-10191025(isoform-parent)|ensembl:ENSG00000007001(gene)|ensembl:ENST00000605860(transcript)|uniprotkb:O95045-2(isoform-parent)	-	crc64:66699F37B0013088	isoform-comment:No experimental confirmation available.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:owY6a3SJ4JVsFePCTPW+NLGK6QQ9606	intact-crc:7BBF28F5A573DEA8|rigid:V72wliDv5yx9hOM+q/HouxwfR5E	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P04179	uniprotkb:P38340	intact:EBI-716989|intact:EBI-1058533|uniprotkb:P78434|uniprotkb:Q16792|uniprotkb:Q5TCM1|uniprotkb:Q96EE6|uniprotkb:Q9P2Z3|uniprotkb:B2R7R1|uniprotkb:E1P5A9|uniprotkb:B3KUK2|uniprotkb:B4E3K9|intact:EBI-11528264|uniprotkb:B4DL20|ensembl:ENSP00000356022|ensembl:ENSP00000446252	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:sodm_human(display_long)|uniprotkb:SOD2(gene name)|psi-mi:SOD2(display_short)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549552|imex:IM-24995-2959	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001019637.1|refseq:NP_000627.2|refseq:NP_001019636.1|refseq:NP_001309743.1|refseq:NP_001309744.1|refseq:NP_001309746.1|refseq:NP_001309748.1|refseq:NP_001309749.1|ensembl:ENSG00000112096(gene)|ensembl:ENST00000367055(transcript)|ensembl:ENST00000538183(transcript)|go:"GO:0000303"(response to superoxide)|go:"GO:0001315"(age-dependent response to reactive oxygen species)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0003069"(acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure)|go:"GO:0003677"(DNA binding)|go:"GO:0004784"(superoxide dismutase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006801"(superoxide metabolic process)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009314"(response to radiation)|go:"GO:0009409"(response to cold)|go:"GO:0010042"(response to manganese ion)|go:"GO:0010043"(response to zinc ion)|go:"GO:0010269"(response to selenium ion)|go:"GO:0010729"(positive regulation of hydrogen peroxide biosynthetic process)|go:"GO:0014823"(response to activity)|go:"GO:0019430"(removal of superoxide radicals)|go:"GO:0019825"(oxygen binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030145"(manganese ion binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0032364"(oxygen homeostasis)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0033591"(response to L-ascorbic acid)|go:"GO:0034021"(response to silicon dioxide)|go:"GO:0035900"(response to isolation stress)|go:"GO:0035902"(response to immobilization stress)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042802"(identical protein binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0050665"(hydrogen peroxide biosynthetic process)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071000"(response to magnetism)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:1902176"(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1902631"(negative regulation of membrane hyperpolarization)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|go:"GO:1905932"(positive regulation of vascular associated smooth muscle cell differentiation involved in phenotypic switching)|interpro:IPR001189(Manganese and iron superoxide dismutase)|interpro:IPR019831|interpro:IPR019832|interpro:IPR019833|interpro:IPR036314|interpro:IPR036324|mint:P04179|rcsb pdb:1AP5|rcsb pdb:1AP6|rcsb pdb:1EM1|rcsb pdb:1JA8|rcsb pdb:1LUV|rcsb pdb:1LUW|rcsb pdb:1MSD|rcsb pdb:1N0J|rcsb pdb:1N0N|rcsb pdb:1PL4|rcsb pdb:1PM9|rcsb pdb:1QNM|rcsb pdb:1SZX|rcsb pdb:1VAR|rcsb pdb:1XDC|rcsb pdb:1XIL|rcsb pdb:1ZTE|rcsb pdb:1ZUQ|rcsb pdb:2ADP|rcsb pdb:2ADQ|rcsb pdb:2GDS|rcsb pdb:2P4K|rcsb pdb:2QKA|rcsb pdb:2QKC|rcsb pdb:3C3S|rcsb pdb:3C3T|rcsb pdb:5GXO|rcsb pdb:5T30|rcsb pdb:5VF9|rcsb pdb:7KKS|rcsb pdb:7KKU|rcsb pdb:7KKW|rcsb pdb:7KLB|reactome:R-HSA-2151201|reactome:R-HSA-3299685|reactome:R-HSA-8862803|reactome:R-HSA-8950505|rcsb pdb:1ZSP|reactome:R-HSA-9615017	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F	-	-	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2018/02/26	rogid:W5bvoLylgk4nEcm5peimceKIBbE9606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:64800374489E3D3B|rigid:exJgdTfj27ljprbIWmnpTK9FJm4	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P38340	uniprotkb:Q7Z6G3-2	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-10172876|ensembl:ENSP00000457354|intact:EBI-14062040	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:q7z6g3-2(display_long)|uniprotkb:EFCBP2(gene name synonym)|uniprotkb:Neuronal calcium-binding protein 2(gene name synonym)|uniprotkb:Synaptotagmin-interacting protein 2(gene name synonym)|uniprotkb:NECAB2(gene name)|psi-mi:NECAB2(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549556|imex:IM-24995-2960	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F	ensembl:ENSG00000103154(gene)|ensembl:ENST00000565691(transcript)|uniprotkb:Q7Z6G3-2(isoform-parent)|intact:EBI-950070(isoform-parent)	-	crc64:66699F37B0013088	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:4S7oIx6h+mKzV3EPxqcfMNqaNko9606	intact-crc:21DD5C257A93AA65|rigid:HePbFZ6mzdKTou/1BHktJZUUsEk	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P12268	uniprotkb:P38340	intact:EBI-353389|uniprotkb:Q6LEF3|ensembl:ENSP00000321584	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:imdh2_human(display_long)|uniprotkb:IMPDH2(gene name)|psi-mi:IMPDH2(display_short)|uniprotkb:IMPD2(gene name synonym)|uniprotkb:Inosine-5'-monophosphate dehydrogenase type II(gene name synonym)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549560|imex:IM-24995-2961	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000875.2|ensembl:ENSG00000178035(gene)|ensembl:ENST00000326739(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003938"(IMP dehydrogenase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006177"(GMP biosynthetic process)|go:"GO:0006183"(GTP biosynthetic process)|go:"GO:0007623"(circadian rhythm)|go:"GO:0016020"(membrane)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042802"(identical protein binding)|go:"GO:0046651"(lymphocyte proliferation)|go:"GO:0046872"(metal ion binding)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR001093(IMP dehydrogenase/GMP reductase)|interpro:IPR005990(IMP dehydrogenase)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR015875(IMP dehydrogenase / GMP reductase, conserved site)|mint:P12268|rcsb pdb:1B3O|rcsb pdb:1NF7|rcsb pdb:1NFB|rcsb pdb:6I0M|rcsb pdb:6I0O|rcsb pdb:6U8E|rcsb pdb:6U8N|rcsb pdb:6U8R|rcsb pdb:6U8S|rcsb pdb:6U9O|rcsb pdb:6UA2|rcsb pdb:6UA4|rcsb pdb:6UA5|rcsb pdb:6UAJ|rcsb pdb:6UC2|rcsb pdb:6UDO|rcsb pdb:6UDP|rcsb pdb:6UDQ|reactome:R-HSA-6798695|reactome:R-HSA-73817|reactome:R-HSA-9679191	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F	-	-	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:qGPwBxhEgtYik3OetHZbpyktoLE9606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:4992325A3952EFE9|rigid:tdNFZkQsBnNk6qxyY9zk21jBHGA	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P07910-2	uniprotkb:P38340	intact:EBI-5280084|ensembl:ENSP00000442816|ensembl:ENSP00000450544|ensembl:ENSP00000450725|ensembl:ENSP00000451176	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:p07910-2(display_long)|uniprotkb:HNRNPC(gene name)|psi-mi:HNRNPC(display_short)|uniprotkb:HNRPC(gene name synonym)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549580|imex:IM-24995-2966	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:P07910-2(isoform-parent)|intact:EBI-357966(isoform-parent)|ensembl:ENSG00000092199(gene)|ensembl:ENST00000430246(transcript)|ensembl:ENST00000553300(transcript)|ensembl:ENST00000554969(transcript)|ensembl:ENST00000556897(transcript)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F	-	isoform-comment:Contains a phosphoserine at position 107. Contains a phosphoserine at position 108.	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:r7AhGozE3aHdynLr8DrXPRtOuyI9606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:B3251EBB0FB46682|rigid:/IqKzh8jrl3ECXJ1Fx+WsR4iX6M	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P38340	uniprotkb:O15217	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-752440|uniprotkb:Q5T7Q8|uniprotkb:Q9BX18|uniprotkb:Q9H414|uniprotkb:B2RD15|uniprotkb:Q6P4G1|ensembl:ENSP00000359998|ensembl:ENSP00000360002	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:gsta4_human(display_long)|uniprotkb:Glutathione S-transferase A4-4(gene name synonym)|uniprotkb:GST class-alpha member 4(gene name synonym)|uniprotkb:GSTA4(gene name)|psi-mi:GSTA4(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549568|imex:IM-24995-2963	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F	refseq:NP_001503.1|refseq:XP_005249092.1|ensembl:ENSG00000170899(gene)|ensembl:ENST00000370959(transcript)|ensembl:ENST00000370963(transcript)|go:"GO:0004364"(glutathione transferase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0006805"(xenobiotic metabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|interpro:IPR003080(Glutathione S-transferase, alpha class)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR036249|interpro:IPR036282|interpro:IPR040079|rcsb pdb:1GUL|rcsb pdb:1GUM|rcsb pdb:3IK7|reactome:R-HSA-156590	-	crc64:66699F37B0013088	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:9yVcqmJL64S0kxOW5RJWbOJ25bo9606	intact-crc:46C529B6F3253B37|rigid:CQe1YtkJPmZO9D7RLFGMIU2cnpo	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P38340	uniprotkb:O95198	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-746999|uniprotkb:B2RD18|uniprotkb:Q8N484|uniprotkb:Q8TBH5|uniprotkb:A6NCM7|uniprotkb:B4DFH7|uniprotkb:F5H6M3|ensembl:ENSP00000226725	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:klhl2_human(display_long)|uniprotkb:Actin-binding protein Mayven(gene name synonym)|uniprotkb:KLHL2(gene name)|psi-mi:KLHL2(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549572|imex:IM-24995-2964	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F	refseq:NP_001154993.1|refseq:NP_001154994.1|refseq:NP_009177.3|refseq:NP_001317952.1|refseq:NP_001317953.1|refseq:XP_016863165.1|ensembl:ENSG00000109466(gene)|ensembl:ENST00000226725(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030027"(lamellipodium)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR017096(Kelch-like protein, gigaxonin)|interpro:IPR044072|mint:O95198|rcsb pdb:2XN4|rcsb pdb:4CHB|reactome:R-HSA-8951664|reactome:R-HSA-983168|go:"GO:0042802"(identical protein binding)	-	crc64:66699F37B0013088	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:tFegR2lJZccRqs4qUjdT3PNjNnk9606	intact-crc:912750C43233614D|rigid:lJxC0eiGxMGHHLeQdu8zDmVW8Ps	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P38340	uniprotkb:A0A0A0MQS1	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-11528247|ensembl:ENSP00000220966|ensembl:ENSP00000484458	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:a0a0a0mqs1_human(display_long)|uniprotkb:PYCR3(gene name)|psi-mi:PYCR3(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549576|imex:IM-24995-2965	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F	refseq:NP_075566.2|ensembl:ENSG00000104524(gene)|ensembl:ENSG00000276657(gene)|ensembl:ENST00000220966(transcript)|ensembl:ENST00000616663(transcript)|go:"GO:0004735"(pyrroline-5-carboxylate reductase activity)|go:"GO:0005829"(cytosol)|go:"GO:0045171"(intercellular bridge)|go:"GO:0055129"(L-proline biosynthetic process)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000304(Delta 1-pyrroline-5-carboxylate reductase)|interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|interpro:IPR028939|interpro:IPR029036|interpro:IPR036291	-	crc64:66699F37B0013088	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:kN384/dufzrR3P6KOXbFMYoj0zc9606	intact-crc:531BCD882D4C4E25|rigid:/WYBpOjvXMEfItB+e7NBTIhhtco	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O95199	uniprotkb:P38340	intact:EBI-742404|uniprotkb:B2RDW8|ensembl:ENSP00000345144	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:rcbt2_human(display_long)|uniprotkb:RCBTB2(gene name)|psi-mi:RCBTB2(display_short)|uniprotkb:CHC1L(gene name synonym)|uniprotkb:RLG(gene name synonym)|uniprotkb:Regulator of chromosome condensation and BTB domain-containing protein 2(gene name synonym)|uniprotkb:Chromosome condensation 1-like(gene name synonym)|uniprotkb:RCC1-like G exchanging factor(gene name synonym)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549600|imex:IM-24995-2971	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001259.1|refseq:NP_001273759.1|refseq:NP_001273760.1|refseq:NP_001273761.1|refseq:XP_005266299.1|refseq:XP_005266301.1|refseq:XP_006719822.1|ensembl:ENSG00000136161(gene)|ensembl:ENST00000344532(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR000408(Regulator of chromosome condensation, RCC1)|interpro:IPR009091(Regulator of chromosome condensation/beta-lactamase-inhibitor protein II)|interpro:IPR011333(BTB/POZ fold)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F	-	-	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:VJjauSy5q9k4V5QceqoSYZQ5ep49606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:D254A724FA63D98D|rigid:AprCXFdpSyNS16xZwsp7R5S4ILk	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P38340	intact:EBI-11528211	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	-	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:enox2(display_short)|psi-mi:EBI-11528211(display_long)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549596|imex:IM-24995-2970	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F	-	-	crc64:66699F37B0013088	no-uniprot-update:	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:mwLMSKBYuz2EZOAkdg8N9MLSkXE9606	intact-crc:86485AF6E8C9187C|rigid:PeR0wVW3EbiAR3iK/a2zYQ0y6iU	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P38340	uniprotkb:E7EUC7	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-11528286|ensembl:ENSP00000411803	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:e7euc7_human(display_long)|uniprotkb:UGP2(gene name)|psi-mi:UGP2(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549584|imex:IM-24995-2967	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F	ensembl:ENSG00000169764(gene)|ensembl:ENST00000445915(transcript)|go:"GO:0003983"("UTP:glucose-1-phosphate uridylyltransferase activity")|go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0006011"(UDP-glucose metabolic process)|interpro:IPR002618(UTP--glucose-1-phosphate uridylyltransferase)|interpro:IPR016267(UTP--glucose-1-phosphate uridylyltransferase, subgroup)|interpro:IPR029044	-	crc64:66699F37B0013088	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:+NfRORYv+EzUaQOJJ7vdI/Plv5o9606	intact-crc:8BD434050B1E2085|rigid:H37AqMtrt28Esz0gavvvEKcGlvM	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O00463	uniprotkb:P38340	intact:EBI-523498|ensembl:ENSP00000261464|ensembl:ENSP00000336825|ensembl:ENSP00000355971|uniprotkb:Q6FHY1|uniprotkb:B4DIS9|uniprotkb:B4E0A2	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:traf5_human(display_long)|uniprotkb:RING finger protein 84(gene name synonym)|uniprotkb:TRAF5(gene name)|psi-mi:TRAF5(display_short)|uniprotkb:RNF84(gene name synonym)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549588|imex:IM-24995-2968	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306136.1|refseq:XP_011508261.1|refseq:XP_011508262.1|ensembl:ENSG00000082512(gene)|ensembl:ENST00000261464(transcript)|ensembl:ENST00000336184(transcript)|ensembl:ENST00000367004(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031996"(thioesterase binding)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035631"(CD40 receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0097400"(interleukin-17-mediated signaling pathway)|interpro:IPR001293(Zinc finger, TRAF-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|interpro:IPR012227(TNF receptor-associated factor TRAF)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018957|interpro:IPR027130|interpro:IPR043211|mint:O00463|rcsb pdb:7L3L|refseq:NP_001029082.1|refseq:NP_004610.1|refseq:NP_665702.1|refseq:XP_016857710.1	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F	-	-	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:xPAQGevMJLEAPcT6eX3n304eSOw9606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:08409071E3A932CC|rigid:pkuLBc2UxLhn82KLCoJBiJlN04M	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O95073-2	uniprotkb:P38340	intact:EBI-10696047	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:o95073-2(display_long)|uniprotkb:FSBP(gene name)|psi-mi:FSBP(display_short)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549592|imex:IM-24995-2969	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-1059030(isoform-parent)|uniprotkb:O95073-2(isoform-parent)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F	-	isoform-comment:No experimental confirmation available.	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:j4ktleFZa7rAjRFENAKAGdAd+Fs9606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:5403806EA7C0807C|rigid:3CHju8AVHoaJuwXoNLMo4eK2jk4	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P38340	uniprotkb:Q96A10	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-10486892|intact:EBI-11528237|ensembl:ENSP00000488921	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:q96a10_human(display_long)|uniprotkb:ERVK3-1(gene name)|psi-mi:ERVK3-1(display_short)|uniprotkb:hCG_2043597(orf name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549612|imex:IM-24995-2974	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F	ensembl:ENSG00000142396(gene)|ensembl:ENST00000427361(transcript)	-	crc64:66699F37B0013088	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/17	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:UGl9ZpnDNz58eECRstJXxM5bj9I9606	intact-crc:8C9F98B068661AE9|rigid:YJyo2r0ijA0z/uAq/mMlfx5VD3o	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O75150	uniprotkb:P38340	intact:EBI-744408|uniprotkb:Q6AHZ6|uniprotkb:Q6N005|uniprotkb:Q7L3T6|uniprotkb:Q8N615|uniprotkb:Q96T18|uniprotkb:Q9BSV9|uniprotkb:Q9HC82|ensembl:ENSP00000325677|uniprotkb:A0A024QZG0	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:bre1b_human(display_long)|uniprotkb:95 kDa retinoblastoma-associated protein(gene name synonym)|uniprotkb:RING finger protein 40(gene name synonym)|uniprotkb:RNF40(gene name)|psi-mi:RNF40(display_short)|uniprotkb:BRE1B(gene name synonym)|uniprotkb:KIAA0661(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase BRE1B(gene name synonym)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549604|imex:IM-24995-2972	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001273501.1|refseq:NP_001193962.1|refseq:NP_001193963.1|refseq:NP_055586.1|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|go:"GO:1902916"(positive regulation of protein polyubiquitination)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013956(E3 ubiquitin ligase, BRE1)|interpro:IPR017907|mint:O75150|reactome:R-HSA-8866654|go:"GO:0046872"(metal ion binding)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0043679"(axon terminus)|go:"GO:0044877"(protein-containing complex binding)|ensembl:ENSG00000103549(gene)|ensembl:ENST00000324685(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016020"(membrane)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0033503"(HULC complex)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F	-	-	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2018/09/18	rogid:POkQZhEBe4cw3Y9V3YOwJDgvYJ89606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:651EE123B57F0552|rigid:Sy3yc2wsAABEI+8dEkNmd7HhUCI	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P02792	uniprotkb:P38340	intact:EBI-713279|uniprotkb:Q7Z2W1|uniprotkb:Q9BTZ8|ensembl:ENSP00000366525|uniprotkb:B2R4B9|uniprotkb:Q6IBT7|uniprotkb:Q86WI9|uniprotkb:Q8WU07|uniprotkb:Q96AU9|uniprotkb:Q96CU0	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:fril_human(display_long)|uniprotkb:FTL(gene name)|psi-mi:FTL(display_short)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549608|imex:IM-24995-2973	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000137.2|ensembl:ENSG00000087086(gene)|ensembl:ENST00000331825(transcript)|go:"GO:0005506"(iron ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006826"(iron ion transport)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0006880"(intracellular sequestering of iron ion)|go:"GO:0008043"(intracellular ferritin complex)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008199"(ferric iron binding)|go:"GO:0016020"(membrane)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0042802"(identical protein binding)|go:"GO:0044754"(autolysosome)|go:"GO:0055072"(iron ion homeostasis)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001519(Ferritin, N-terminal)|interpro:IPR008331(Ferritin and Dps)|interpro:IPR009040(Ferritin-like)|interpro:IPR009078(Ferritin/ribonucleotide reductase-like)|interpro:IPR012347(Ferritin-related)|interpro:IPR014034(Ferritin, conserved site)|mint:P02792|rcsb pdb:2FFX|rcsb pdb:2FG4|rcsb pdb:2FG8|rcsb pdb:3KXU|rcsb pdb:4V6B|rcsb pdb:5LG8|rcsb pdb:6TR9|rcsb pdb:6TS0|rcsb pdb:6TS1|rcsb pdb:6TSA|rcsb pdb:6TSF|rcsb pdb:6TSJ|rcsb pdb:6WX6|reactome:R-HSA-3000480|reactome:R-HSA-432722|reactome:R-HSA-6798695|reactome:R-HSA-917937|dip:DIP-31248N	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F	-	-	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:+mbnoETQ9TuBZg8Gc09nwAjwKTE9606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:0648CD223E3C522A|rigid:WAT4Ve4kETxjryeBc7GwTF2nUqk	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P15531	uniprotkb:P38340	intact:EBI-741141|ensembl:ENSP00000376892|uniprotkb:Q6FGK3|uniprotkb:Q86XQ2|uniprotkb:Q9UDJ6	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:ndka_human(display_long)|uniprotkb:Tumor metastatic process-associated protein(gene name synonym)|uniprotkb:Metastasis inhibition factor nm23(gene name synonym)|uniprotkb:Granzyme A-activated DNase(gene name synonym)|uniprotkb:NME1(gene name)|psi-mi:NME1(display_short)|uniprotkb:NDPKA(gene name synonym)|uniprotkb:NM23(gene name synonym)|uniprotkb:NM23-H1(gene name synonym)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549628|imex:IM-24995-2978	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000260.1|refseq:NP_937818.1|ensembl:ENSG00000239672(gene)|ensembl:ENST00000393196(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0002762"(negative regulation of myeloid leukocyte differentiation)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004536"(deoxyribonuclease activity)|go:"GO:0004550"(nucleoside diphosphate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0006183"(GTP biosynthetic process)|go:"GO:0006228"(UTP biosynthetic process)|go:"GO:0006241"(CTP biosynthetic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007595"(lactation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014075"(response to amine)|go:"GO:0016020"(membrane)|go:"GO:0019215"(intermediate filament binding)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051591"(response to cAMP)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071398"(cellular response to fatty acid)|interpro:IPR001564(Nucleoside diphosphate kinase, core)|go:"GO:0019899"(enzyme binding)|interpro:IPR023005|go:"GO:0021766"(hippocampus development)|interpro:IPR034907|interpro:IPR036850|mint:P15531|go:"GO:0030154"(cell differentiation)|go:"GO:0032587"(ruffle membrane)|rcsb pdb:1JXV|rcsb pdb:1UCN|go:"GO:0033574"(response to testosterone)|go:"GO:0035690"|rcsb pdb:2HVD|rcsb pdb:2HVE|rcsb pdb:3L7U|rcsb pdb:4ENO|rcsb pdb:5UI4|reactome:R-HSA-499943|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043024"(ribosomal small subunit binding)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|dip:DIP-39164N	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F	-	-	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:Ut4gK1Xq786CaZzvqdS1eiU5op89606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:A19B92B650A3F2B2|rigid:An9Y00CWrtenqHtdvGrjdLIdIfk	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P38340	intact:EBI-11528223	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	-	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:znf471(display_short)|psi-mi:EBI-11528223(display_long)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549616|imex:IM-24995-2975	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F	-	-	crc64:66699F37B0013088	no-uniprot-update:	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:x1KdEVhuKo5sZGVPBGE9eyTup9w9606	intact-crc:B05D20DDBEF1D6F3|rigid:6nI/DovSV6EE/RcJSsHhQqjEH8g	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8N5R6	uniprotkb:P38340	intact:EBI-740841|intact:EBI-953781|uniprotkb:B3KQ49|uniprotkb:A8K3U4|uniprotkb:A8MPQ6|uniprotkb:A8MV61|uniprotkb:A8MVU9|uniprotkb:Q9H5Q6|uniprotkb:Q8TAX6|intact:EBI-2320546|intact:EBI-11522976	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:ccd33_human(display_long)|uniprotkb:CCDC33(gene name)|psi-mi:CCDC33(display_short)|uniprotkb:Cancer/testis antigen 61(gene name synonym)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549620|imex:IM-24995-2976	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_079331.3|interpro:IPR000008(C2 calcium-dependent membrane targeting)|go:"GO:0005777"(peroxisome)|refseq:NP_001274110.1|refseq:NP_877592.2|mint:Q8N5R6|interpro:IPR035892|interpro:IPR039889	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F	-	-	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2021/11/30	rogid:eEIn7pQyfdHWx8TeLJpYy0i/gww9606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:2D3AEAAEA30207CA|rigid:WXW+UkaLERQjfcPvEM30JXP5Ay8	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O75525	uniprotkb:P38340	intact:EBI-722504|uniprotkb:Q6NUL8|uniprotkb:Q9UPA8|ensembl:ENSP00000348108	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:khdr3_human(display_long)|uniprotkb:Sam68-like mammalian protein 2(gene name synonym)|uniprotkb:Sam68-like phosphotyrosine protein(gene name synonym)|uniprotkb:RNA-binding protein T-Star(gene name synonym)|uniprotkb:KHDRBS3(gene name)|psi-mi:KHDRBS3(display_short)|uniprotkb:SALP(gene name synonym)|uniprotkb:SLM2(gene name synonym)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549624|imex:IM-24995-2977	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006549.1|ensembl:ENSG00000131773(gene)|ensembl:ENST00000355849(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR032335|interpro:IPR032571|interpro:IPR036612|mint:O75525|rcsb pdb:5EL3|rcsb pdb:5ELR|rcsb pdb:5ELS|rcsb pdb:5ELT|rcsb pdb:5EMO|reactome:R-HSA-8849468	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F	-	-	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:9ZoB3JVp0Q9nxeFRsmWhNThzWoE9606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:841E9DB63A9D6BA3|rigid:HE8C5amJM/2YjlkjyDW3gJAZjtA	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P38340	uniprotkb:P38432	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-945751|uniprotkb:B2R931|ensembl:ENSP00000240316	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:coil_human(display_long)|uniprotkb:COIL(gene name)|psi-mi:COIL(display_short)|uniprotkb:CLN80(gene name synonym)|uniprotkb:p80-coilin(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549644|imex:IM-24995-2982	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F	refseq:NP_004636.1|dip:DIP-38503N|ensembl:ENSG00000121058(gene)|ensembl:ENST00000240316(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0015030"(Cajal body)|go:"GO:0016020"(membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0030619"(U1 snRNA binding)|go:"GO:0030620"(U2 snRNA binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR024822|interpro:IPR031722|mint:P38432	-	crc64:66699F37B0013088	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:hd5p6AbyA/GYNEeca99Mdb41qM09606	intact-crc:BCE6C22BE335A0B2|rigid:LampXM0o/TLDnA7/30h35Wyu4V4	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P38340	uniprotkb:P07910	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-357966|uniprotkb:P22628|uniprotkb:Q53EX2|uniprotkb:Q59FD3|uniprotkb:Q5FWE8|uniprotkb:Q86SF8|uniprotkb:Q86U45|uniprotkb:Q96HK7|uniprotkb:Q96HM4|uniprotkb:Q96IY5|uniprotkb:Q9BTS3|uniprotkb:D3DS19|uniprotkb:D3DS22|intact:EBI-28976506|ensembl:ENSP00000404848|ensembl:ENSP00000451291|ensembl:ENSP00000452276	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:hnrpc_human(display_long)|uniprotkb:HNRNPC(gene name)|psi-mi:HNRNPC(display_short)|uniprotkb:HNRPC(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549632|imex:IM-24995-2979	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F	refseq:NP_001070910.1|refseq:NP_001070911.1|refseq:NP_004491.2|refseq:NP_112604.2|ensembl:ENSP00000404848|ensembl:ENST00000430246|ensembl:ENSP00000442816|ensembl:ENST00000553300|ensembl:ENSP00000450544|ensembl:ENSP00000451291|ensembl:ENST00000554969|ensembl:ENSP00000452276|ensembl:ENSP00000450725|ensembl:ENST00000555883|ensembl:ENSP00000450629|ensembl:ENST00000556628|ensembl:ENSP00000451652|ensembl:ENST00000556897|ensembl:ENSP00000451176|refseq:XP_011535010.1|refseq:XP_011535011.1|refseq:XP_011535012.1|refseq:XP_011535013.1|refseq:XP_011535014.1|refseq:XP_016876741.1|refseq:XP_016876742.1|dip:DIP-29854N|refseq:XP_006720188.1|ensembl:ENSG00000092199(gene)|ensembl:ENST00000420743(transcript)|ensembl:ENST00000554455(transcript)|ensembl:ENST00000557201(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000785"(chromatin)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005829"(cytosol)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0008380"(RNA splicing)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043044"|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070935"(3'-UTR-mediated mRNA stabilization)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990247"(N6-methyladenosine-containing RNA binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR017347(Heterogeneous nuclear ribonucleoprotein C, Raly)|interpro:IPR035979|mint:P07910|rcsb pdb:1TXP|rcsb pdb:1WF2|rcsb pdb:2MXY|rcsb pdb:2MZ1|rcsb pdb:3LN4|reactome:R-HSA-4570464|reactome:R-HSA-72163|reactome:R-HSA-72203|reactome:R-HSA-9013418|reactome:R-HSA-9013422	-	crc64:66699F37B0013088	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:Fj5tiH0wrNUjTnsURIg8dB8laMg9606	intact-crc:747869B05B25E1AC|rigid:/dGmj8DEWCpiwUdODoXbKQWMeJI	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P35520	uniprotkb:P38340	intact:EBI-740135|uniprotkb:Q99425|uniprotkb:Q9BWC5|uniprotkb:B2R993|uniprotkb:D3DSK4|intact:EBI-14245939|ensembl:ENSP00000344460|ensembl:ENSP00000352643|ensembl:ENSP00000381225|ensembl:ENSP00000381231	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:cbs_human(display_long)|uniprotkb:CBS(gene name)|psi-mi:CBS(display_short)|uniprotkb:Serine sulfhydrase(gene name synonym)|uniprotkb:Beta-thionase(gene name synonym)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549636|imex:IM-24995-2980	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000062.1|refseq:NP_001171479.1|refseq:NP_001171480.1|ensembl:ENSG00000160200(gene)|ensembl:ENST00000352178(transcript)|ensembl:ENST00000359624(transcript)|ensembl:ENST00000398158(transcript)|go:"GO:0004122"(cystathionine beta-synthase activity)|ensembl:ENST00000398165(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006535"(cysteine biosynthetic process from serine)|go:"GO:0006563"(L-serine metabolic process)|go:"GO:0006565"(L-serine catabolic process)|go:"GO:0019343"(cysteine biosynthetic process via cystathionine)|go:"GO:0019344"(cysteine biosynthetic process)|go:"GO:0019346"(transsulfuration)|go:"GO:0019448"(L-cysteine catabolic process)|go:"GO:0019825"(oxygen binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0020037"(heme binding)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042262"(DNA protection)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043418"(homocysteine catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0050421"("nitrite reductase (NO-forming) activity")|go:"GO:0050667"(homocysteine metabolic process)|go:"GO:0070025"(carbon monoxide binding)|go:"GO:0070026"(nitric oxide binding)|go:"GO:0070814"(hydrogen sulfide biosynthetic process)|go:"GO:0072341"(modified amino acid binding)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR001216(Cysteine synthase/cystathionine beta-synthase P-phosphate-binding site)|interpro:IPR001926(Pyridoxal phosphate-dependent enzyme, beta subunit)|interpro:IPR005857(Cystathionine beta-synthase)|interpro:IPR036052|mint:P35520|rcsb pdb:1JBQ|rcsb pdb:1M54|rcsb pdb:4COO|rcsb pdb:4L0D|rcsb pdb:4L27|rcsb pdb:4L28|rcsb pdb:4L3V|rcsb pdb:4PCU|rcsb pdb:4UUU|rcsb pdb:5MMS|reactome:R-HSA-1614603|reactome:R-HSA-2408508|refseq:XP_011528079.1|refseq:XP_011528083.1|refseq:XP_011528084.1|refseq:XP_011544396.1|refseq:XP_011544397.1|refseq:XP_011544399.1|refseq:XP_011544400.1|refseq:XP_011544401.1|refseq:NP_001307227.1|refseq:NP_001308002.1|refseq:XP_016883700.1|refseq:XP_016883701.1|refseq:XP_016883702.1|refseq:XP_016883703.1|refseq:XP_016883704.1|refseq:XP_016883705.1|refseq:XP_016883706.1|refseq:XP_016883707.1|refseq:XP_016883978.1|refseq:XP_016883979.1|refseq:XP_016883980.1|refseq:XP_016883981.1	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F	-	-	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:f9eo0cPOHppVY7Nqejag3YyK18s9606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:E913024F38E6E30C|rigid:UctRQejoRQJyfKCSH+eIvdt/Fx0	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P38340	uniprotkb:P00492	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-748210|uniprotkb:A6NHF0|uniprotkb:B2R8M9|ensembl:ENSP00000298556	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:hprt_human(display_long)|uniprotkb:HPRT1(gene name)|psi-mi:HPRT1(display_short)|uniprotkb:HPRT(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549640|imex:IM-24995-2981	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F	refseq:NP_000185.1|ensembl:ENSG00000165704(gene)|ensembl:ENST00000298556(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001913"(T cell mediated cytotoxicity)|go:"GO:0001975"(response to amphetamine)|go:"GO:0004422"(hypoxanthine phosphoribosyltransferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006164"(purine nucleotide biosynthetic process)|go:"GO:0006166"(purine ribonucleoside salvage)|go:"GO:0006168"(adenine salvage)|go:"GO:0006178"(guanine salvage)|go:"GO:0007625"(grooming behavior)|go:"GO:0007626"(locomotory behavior)|go:"GO:0021756"(striatum development)|go:"GO:0021895"(cerebral cortex neuron differentiation)|go:"GO:0021954"(central nervous system neuron development)|go:"GO:0032263"(GMP salvage)|go:"GO:0032264"(IMP salvage)|go:"GO:0042417"(dopamine metabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043103"(hypoxanthine salvage)|go:"GO:0045964"(positive regulation of dopamine metabolic process)|go:"GO:0046038"(GMP catabolic process)|go:"GO:0046040"(IMP metabolic process)|go:"GO:0046100"(hypoxanthine metabolic process)|go:"GO:0046651"(lymphocyte proliferation)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0052657"(guanine phosphoribosyltransferase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000836(Phosphoribosyltransferase)|interpro:IPR005904(Hypoxanthine phosphoribosyl transferase)|interpro:IPR029057|mint:P00492|rcsb pdb:1BZY|rcsb pdb:1D6N|rcsb pdb:1HMP|rcsb pdb:1Z7G|go:"GO:0048813"(dendrite morphogenesis)|rcsb pdb:2VFA|rcsb pdb:3GEP|rcsb pdb:3GGC|rcsb pdb:3GGJ|rcsb pdb:4IJQ|rcsb pdb:4KN6|rcsb pdb:4RAB|rcsb pdb:4RAC|rcsb pdb:4RAD|rcsb pdb:4RAN|rcsb pdb:4RAO|rcsb pdb:4RAQ|rcsb pdb:5BRN|rcsb pdb:5BSK|rcsb pdb:5HIA|rcsb pdb:5W8V|rcsb pdb:6BNJ|reactome:R-HSA-74217	-	crc64:66699F37B0013088	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:w87Sv/qOAkHFqJm0vu0Ayqlz7TA9606	intact-crc:30642C3A233253DA|rigid:kN3HSjFHCL+psSPe3dh3+6GQJ0o	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P38732	uniprotkb:P38432	intact:EBI-24379|uniprotkb:D3DKT0|ensemblfungi:YHL039W	intact:EBI-945751|uniprotkb:B2R931|ensembl:ENSP00000240316	psi-mi:efm1_yeast(display_long)|uniprotkb:EFM1(gene name)|psi-mi:EFM1(display_short)|uniprotkb:Elongation factor methyltransferase 1(gene name synonym)|uniprotkb:YHL039W(locus name)	psi-mi:coil_human(display_long)|uniprotkb:COIL(gene name)|psi-mi:COIL(display_short)|uniprotkb:CLN80(gene name synonym)|uniprotkb:p80-coilin(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549660|imex:IM-24995-2986	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011824.1|sgd:S000001031|dip:DIP-6582N|mint:P38732|ensemblfungi:YHL039W(gene)|ensemblfungi:YHL039W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0018026"(peptidyl-lysine monomethylation)|go:"GO:0018027"(peptidyl-lysine dimethylation)|interpro:IPR001214(SET)|interpro:IPR017119(Ribosomal lysine methyltransferase 1)|interpro:IPR044432	refseq:NP_004636.1|dip:DIP-38503N|ensembl:ENSG00000121058(gene)|ensembl:ENST00000240316(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0015030"(Cajal body)|go:"GO:0016020"(membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0030619"(U1 snRNA binding)|go:"GO:0030620"(U2 snRNA binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR024822|interpro:IPR031722|mint:P38432	-	crc64:84BC2D3A204D9D29	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:e5E4ijHZAIzzKWrxCzPqifR2v8U559292	rogid:hd5p6AbyA/GYNEeca99Mdb41qM09606	intact-crc:A8DBFF6E2E537D92|rigid:g8DjAPiY7s/Ez4qEL6eO+HZ0ojI	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P38432	uniprotkb:P32502	intact:EBI-945751|uniprotkb:B2R931|ensembl:ENSP00000240316	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:coil_human(display_long)|uniprotkb:COIL(gene name)|psi-mi:COIL(display_short)|uniprotkb:CLN80(gene name synonym)|uniprotkb:p80-coilin(gene name synonym)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549648|imex:IM-24995-2983	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004636.1|dip:DIP-38503N|ensembl:ENSG00000121058(gene)|ensembl:ENST00000240316(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0015030"(Cajal body)|go:"GO:0016020"(membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0030619"(U1 snRNA binding)|go:"GO:0030620"(U2 snRNA binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR024822|interpro:IPR031722|mint:P38432	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731	-	-	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:hd5p6AbyA/GYNEeca99Mdb41qM09606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:C9E21A4F22C4C121|rigid:xh14u3vqTThWSaUBxfd/0lTwQwA	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P25377	uniprotkb:P38432	intact:EBI-2347652|uniprotkb:D6VRA5|ensemblfungi:YCR105W	intact:EBI-945751|uniprotkb:B2R931|ensembl:ENSP00000240316	psi-mi:adh7_yeast(display_long)|uniprotkb:ADH7(gene name)|psi-mi:ADH7(display_short)|uniprotkb:NADP-dependent alcohol dehydrogenase VII(gene name synonym)|uniprotkb:YCR105W(locus name)	psi-mi:coil_human(display_long)|uniprotkb:COIL(gene name)|psi-mi:COIL(display_short)|uniprotkb:CLN80(gene name synonym)|uniprotkb:p80-coilin(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549652|imex:IM-24995-2984	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010030.1|sgd:S000000702|dip:DIP-7661N|mint:P25377|ensemblfungi:YCR105W(gene)|ensemblfungi:YCR105W_mRNA(transcript)|go:"GO:0006066"(alcohol metabolic process)|go:"GO:0008106"("alcohol dehydrogenase (NADP+) activity")|go:"GO:0008270"(zinc ion binding)|go:"GO:0016616"(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|interpro:IPR002328(Alcohol dehydrogenase, zinc-containing, conserved site)|interpro:IPR011032(GroES-like)|interpro:IPR013149(Alcohol dehydrogenase, zinc-binding)|interpro:IPR013154(Alcohol dehydrogenase GroES-like)|interpro:IPR020843|interpro:IPR029752|interpro:IPR036291	refseq:NP_004636.1|dip:DIP-38503N|ensembl:ENSG00000121058(gene)|ensembl:ENST00000240316(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0015030"(Cajal body)|go:"GO:0016020"(membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0030619"(U1 snRNA binding)|go:"GO:0030620"(U2 snRNA binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR024822|interpro:IPR031722|mint:P38432	-	crc64:BFB0E6C5F93D3F07	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:PGCt+bqhn63vUVgS5IKrrOukXgg559292	rogid:hd5p6AbyA/GYNEeca99Mdb41qM09606	intact-crc:D51B88E8BDB97D2D|rigid:f+UCxJGH8DarSYA0nEMYqaC7YRI	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P38646	uniprotkb:P38340	intact:EBI-354932|ensembl:ENSP00000297185|uniprotkb:P30036|uniprotkb:P31932|uniprotkb:Q6GU03|uniprotkb:Q9BWB7|uniprotkb:B2RCM1|uniprotkb:Q1HB43|uniprotkb:Q53H23|uniprotkb:Q9UC56	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:grp75_human(display_long)|uniprotkb:HSPA9(gene name)|psi-mi:HSPA9(display_short)|uniprotkb:GRP75(gene name synonym)|uniprotkb:HSPA9B(gene name synonym)|uniprotkb:75 kDa glucose-regulated protein(gene name synonym)|uniprotkb:Heat shock 70 kDa protein 9(gene name synonym)|uniprotkb:Peptide-binding protein 74(gene name synonym)|uniprotkb:Mortalin(gene name synonym)|uniprotkb:mt-HSP70(gene name synonym)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549656|imex:IM-24995-2985	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	reactome:R-HSA-8949613|reactome:R-HSA-8950505|ensembl:ENSG00000113013(gene)|ensembl:ENST00000297185(transcript)|go:"GO:0001401"(SAM complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005925"(focal adhesion)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0007007"(inner mitochondrial membrane organization)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045646"(regulation of erythrocyte differentiation)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0140275"(MIB complex)|go:"GO:1902037"(negative regulation of hematopoietic stem cell differentiation)|go:"GO:1903707"(negative regulation of hemopoiesis)|interpro:IPR012725(Chaperone DnaK)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|go:"GO:0070062"(extracellular exosome)|interpro:IPR043129|mint:P38646|rcsb pdb:3N8E|rcsb pdb:4KBO|rcsb pdb:6NHK|rcsb pdb:6P2U|rcsb pdb:6PMT|reactome:R-HSA-1268020|reactome:R-HSA-3371453|refseq:NP_004125.3|dip:DIP-32936N	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F	-	-	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:xjSHeTKBb/lH1XNEEiMIjsM+XcE9606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:54855C6761D5046A|rigid:pM5gDg0qNFxvRHzy6g57D7kSfCw	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P38792	uniprotkb:G5E962	intact:EBI-1757|uniprotkb:D3DL18|ensemblfungi:YHR069C	intact:EBI-11525615|ensembl:ENSP00000328177	psi-mi:rrp4_yeast(display_long)|uniprotkb:RRP4(gene name)|psi-mi:RRP4(display_short)|uniprotkb:Ribosomal RNA-processing protein 4(gene name synonym)|uniprotkb:YHR069C(locus name)	psi-mi:g5e962_human(display_long)|uniprotkb:hCG_1644200(orf name)|uniprotkb:MAGEA11(gene name)|psi-mi:MAGEA11(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549676|imex:IM-24995-2990	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011936.1|sgd:S000001111|dip:DIP-5888N|mint:P38792|ensemblfungi:YHR069C(gene)|ensemblfungi:YHR069C_mRNA(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0071034"(CUT catabolic process)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071049"|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR004088(K Homology, type 1)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR025721|interpro:IPR026699|interpro:IPR036612|rcsb pdb:4IFD|rcsb pdb:4OO1|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5G06|rcsb pdb:5JEA|rcsb pdb:5K36|rcsb pdb:5OKZ|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-429958|reactome:R-SCE-450385|reactome:R-SCE-450513|reactome:R-SCE-6791226	refseq:NP_001011544.1|ensembl:ENSG00000185247(gene)|ensembl:ENST00000333104(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016604"(nuclear body)|interpro:IPR002190(MAGE protein)|interpro:IPR021072|interpro:IPR030099|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899	-	crc64:0718A7ABF42E9B9B	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:ZgBS9xjR7jC96sAb0m63ElPvM7M559292	rogid:sVB0aA6yibWUx/d2SE+pwpKKgtI9606	intact-crc:8F8BEB8DEB1DD7CF|rigid:IDlrQJoGydTypSzPj8mX6Azug1k	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O75569	uniprotkb:P38732	intact:EBI-713955|ensembl:ENSP00000318176|uniprotkb:Q53G24|uniprotkb:Q6X7T5|uniprotkb:Q8NDK4|uniprotkb:A8K3I6	intact:EBI-24379|uniprotkb:D3DKT0|ensemblfungi:YHL039W	psi-mi:prkra_human(display_long)|uniprotkb:Protein activator of the interferon-induced protein kinase(gene name synonym)|uniprotkb:PKR-associated protein X(gene name synonym)|uniprotkb:PKR-associating protein X(gene name synonym)|uniprotkb:HSD-14(orf name)|uniprotkb:PRKRA(gene name)|psi-mi:PRKRA(display_short)|uniprotkb:RAX(gene name synonym)|uniprotkb:PACT(gene name synonym)|uniprotkb:HSD14(orf name)|uniprotkb:Protein kinase, interferon-inducible double-stranded RNA-dependent activator(gene name synonym)	psi-mi:efm1_yeast(display_long)|uniprotkb:EFM1(gene name)|psi-mi:EFM1(display_short)|uniprotkb:Elongation factor methyltransferase 1(gene name synonym)|uniprotkb:YHL039W(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549664|imex:IM-24995-2987	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006955"(immune response)|go:"GO:0008047"(enzyme activator activity)|ensembl:ENSG00000180228(gene)|ensembl:ENST00000325748(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030422"(production of siRNA involved in RNA interference)|go:"GO:0031054"(pre-miRNA processing)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035196"(production of miRNAs involved in gene silencing by miRNA)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042474"(middle ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:0050821"(protein stabilization)|go:"GO:0070578"(RISC-loading complex)|go:"GO:0070883"(pre-miRNA binding)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR032478|interpro:IPR033363|interpro:IPR044465|interpro:IPR044466|interpro:IPR044467|mint:O75569|rcsb pdb:2DIX|reactome:R-HSA-203927|reactome:R-HSA-426486|refseq:NP_001132989.1|refseq:NP_001132990.1|refseq:NP_003681.1|dip:DIP-41809N	refseq:NP_011824.1|sgd:S000001031|dip:DIP-6582N|mint:P38732|ensemblfungi:YHL039W(gene)|ensemblfungi:YHL039W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0018026"(peptidyl-lysine monomethylation)|go:"GO:0018027"(peptidyl-lysine dimethylation)|interpro:IPR001214(SET)|interpro:IPR017119(Ribosomal lysine methyltransferase 1)|interpro:IPR044432	-	-	crc64:84BC2D3A204D9D29	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:tZfziopZlC+1d3De97G3kDY+Tog9606	rogid:e5E4ijHZAIzzKWrxCzPqifR2v8U559292	intact-crc:45C08B0BA35817B2|rigid:a/LTA+bxGClszC704i1ljQY/RaQ	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P38744	uniprotkb:O76083-2	intact:EBI-13396|uniprotkb:D3DKR5|ensemblfungi:YHL018W	intact:EBI-11524542|ensembl:ENSP00000335242	psi-mi:phs_yeast(display_long)|uniprotkb:4-alpha-hydroxy-tetrahydropterin dehydratase(gene name synonym)|uniprotkb:Pterin carbinolamine dehydratase(gene name synonym)|uniprotkb:YHL018W(locus name)	psi-mi:o76083-2(display_long)|uniprotkb:PDE9A(gene name)|psi-mi:PDE9A(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549668|imex:IM-24995-2988	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011845.1|sgd:S000001010|interpro:IPR036428|interpro:IPR001533(Transcriptional coactivator/pterin dehydratase)|ensemblfungi:YHL018W(gene)|ensemblfungi:YHL018W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0008124"(4-alpha-hydroxytetrahydrobiopterin dehydratase activity)|dip:DIP-1872N|reactome:R-SCE-8964208	intact:EBI-742764(isoform-parent)|ensembl:ENSG00000160191(gene)|ensembl:ENST00000335512(transcript)|uniprotkb:O76083-2(isoform-parent)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:7+JuLX1wFw/tkE4NcSCTK62b4DU559292	rogid:nTzgeYGOwTM/7VJUgxSnlnDiCFo9606	intact-crc:78057C8DE2443F30|rigid:SeKXelifYejMqVdZovbthoJLm68	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P10644	uniprotkb:P38756	intact:EBI-476431|uniprotkb:Q567S7|uniprotkb:K7ER48|ensembl:ENSP00000351410|ensembl:ENSP00000376475|ensembl:ENSP00000445625|ensembl:ENSP00000464977|ensembl:ENSP00000466459	intact:EBI-24431|uniprotkb:D3DKU6|ensemblfungi:YHR003C	psi-mi:kap0_human(display_long)|uniprotkb:Tissue-specific extinguisher 1(gene name synonym)|uniprotkb:PRKAR1A(gene name)|psi-mi:PRKAR1A(display_short)|uniprotkb:PKR1(gene name synonym)|uniprotkb:PRKAR1(gene name synonym)|uniprotkb:TSE1(gene name synonym)	psi-mi:tcd1_yeast(display_long)|uniprotkb:TCD1(gene name)|psi-mi:TCD1(display_short)|uniprotkb:"t(6)A37 dehydratase 1"(gene name synonym)|uniprotkb:YHR003C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549672|imex:IM-24995-2989	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002725.1|refseq:NP_997636.1|refseq:NP_997637.1|refseq:XP_011523285.1|refseq:XP_011523286.1|refseq:XP_011523287.1|refseq:NP_001263218.1|refseq:NP_001263219.1|refseq:NP_001265362.1|dip:DIP-34368N|ensembl:ENSG00000108946(gene)|ensembl:ENST00000358598(transcript)|ensembl:ENST00000392711(transcript)|ensembl:ENST00000536854(transcript)|ensembl:ENST00000586397(transcript)|ensembl:ENST00000589228(transcript)|go:"GO:0001707"(mesoderm formation)|go:"GO:0004862"(cAMP-dependent protein kinase inhibitor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005771"(multivesicular body)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005952"(cAMP-dependent protein kinase complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007143"(female meiotic nuclear division)|go:"GO:0008603"(cAMP-dependent protein kinase regulator activity)|go:"GO:0010738"(regulation of protein kinase A signaling)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030552"(cAMP binding)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043949"(regulation of cAMP-mediated signaling)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045835"(negative regulation of meiotic nuclear division)|go:"GO:0046007"(negative regulation of activated T cell proliferation)|go:"GO:0060038"(cardiac muscle cell proliferation)|go:"GO:0097224"(sperm connecting piece)|go:"GO:0097546"(ciliary base)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:2000480"(negative regulation of cAMP-dependent protein kinase activity)|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR003117(cAMP-dependent protein kinase, regulatory subunit, type I/II alpha/beta)|interpro:IPR012198(cAMP-dependent protein kinase regulatory subunit)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR018488|rcsb pdb:5KJZ|reactome:R-HSA-163615|reactome:R-HSA-164378|reactome:R-HSA-180024|reactome:R-HSA-381676|reactome:R-HSA-432040|reactome:R-HSA-442720|reactome:R-HSA-5610787|reactome:R-HSA-9660821|reactome:R-HSA-9664323|reactome:R-HSA-983231|interpro:IPR018490|mint:P10644|rcsb pdb:5KJX|rcsb pdb:5KJY	refseq:NP_011866.1|sgd:S000001045|dip:DIP-4417N|mint:P38756|ensemblfungi:YHR003C(gene)|ensemblfungi:YHR003C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0008641"(ubiquitin-like modifier activating enzyme activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0061503"(tRNA threonylcarbamoyladenosine dehydratase)|go:"GO:0061504"(cyclic threonylcarbamoyladenosine biosynthetic process)|interpro:IPR000594(UBA/THIF-type NAD/FAD binding fold)|interpro:IPR035985	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:dUZaCJQnC0KZEG4pccIqoT066VY9606	rogid:Mce7jBtBDJ9bSrw+cQDCbhK8DvY559292	intact-crc:CF5231178A25F4B6|rigid:OXtZ/T6SUL0umW5fFMkbi7YCawM	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P39009	uniprotkb:O00444	intact:EBI-6194|uniprotkb:D6VRP9|ensemblfungi:YDL101C	intact:EBI-746202|uniprotkb:Q8IYF0|uniprotkb:Q96Q95|uniprotkb:B2RAL0|uniprotkb:B7Z837|uniprotkb:B7Z8G7|uniprotkb:Q9UD84|uniprotkb:Q9UDE2|ensembl:ENSP00000270861	psi-mi:dun1_yeast(display_long)|uniprotkb:DUN1(gene name)|psi-mi:DUN1(display_short)|uniprotkb:D2370(orf name)|uniprotkb:YDL101C(locus name)	psi-mi:plk4_human(display_long)|uniprotkb:Polo-like kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase Sak(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 18(gene name synonym)|uniprotkb:PLK4(gene name)|psi-mi:PLK4(display_short)|uniprotkb:SAK(gene name synonym)|uniprotkb:STK18(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549696|imex:IM-24995-2995	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010182.1|sgd:S000002259|dip:DIP-1772N|reactome:R-SCE-5693565|reactome:R-SCE-69473|reactome:R-SCE-69601|reactome:R-SCE-75035|ensemblfungi:YDL101C(gene)|ensemblfungi:YDL101C_mRNA(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0042770"(signal transduction in response to DNA damage)|go:"GO:0044773"(mitotic DNA damage checkpoint signaling)|go:"GO:0048478"(replication fork protection)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000253(Forkhead-associated)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:2JQJ|rcsb pdb:2JQL	refseq:NP_001177728.1|refseq:NP_001177730.1|refseq:NP_055079.3|dip:DIP-34467N|rcsb pdb:5LHZ|rcsb pdb:6N45|rcsb pdb:6N46|rcsb pdb:6W38|rcsb pdb:6W3I|rcsb pdb:6W3J|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|rcsb pdb:5LHY|reactome:R-HSA-5620912|reactome:R-HSA-8854518|ensembl:ENSG00000142731(gene)|ensembl:ENST00000270861(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0001741"(XY body)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007099"(centriole replication)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0046601"(positive regulation of centriole replication)|go:"GO:0060271"(cilium assembly)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0098535"(de novo centriole assembly involved in multi-ciliated epithelial cell differentiation)|go:"GO:0098536"(deuterosome)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033696|interpro:IPR033698|interpro:IPR033699|interpro:IPR033700|mint:O00444|rcsb pdb:2N19|rcsb pdb:3COK|rcsb pdb:4JXF|rcsb pdb:4N7V|rcsb pdb:4N7Z|rcsb pdb:4N9J|rcsb pdb:4YUR|rcsb pdb:4YYP	-	crc64:4990F24F024702D7	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:/BmlSDRdkj7efDRuXH/qWpdTv/U559292	rogid:xqjVEnoGXDk/+2AzLRAkyPK80OI9606	intact-crc:8DA41B99DEEE2009|rigid:3TXIx6nf/xaNuijN+DIwGHgtYHI	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O14641	uniprotkb:P38891	intact:EBI-740850|ensembl:ENSP00000005340|uniprotkb:Q53XM0|uniprotkb:D3DTN3	intact:EBI-3455|uniprotkb:D3DLF7|ensemblfungi:YHR208W	psi-mi:dvl2_human(display_long)|uniprotkb:DSH homolog 2(gene name synonym)|uniprotkb:DVL2(gene name)|psi-mi:DVL2(display_short)	psi-mi:bca1_yeast(display_long)|uniprotkb:Protein TWT1(gene name synonym)|uniprotkb:Protein ECA39(gene name synonym)|uniprotkb:BAT1(gene name)|psi-mi:BAT1(display_short)|uniprotkb:ECA39(gene name synonym)|uniprotkb:TWT1(gene name synonym)|uniprotkb:YHR208W(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549692|imex:IM-24995-2994	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004413.1|ensembl:ENSG00000004975(gene)|ensembl:ENST00000005340(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005109"(frizzled binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0007507"(heart development)|go:"GO:0016235"(aggresome)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044340"(canonical Wnt signaling pathway involved in regulation of cell proliferation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0150012"(positive regulation of neuron projection arborization)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008341(Dishevelled-2 region)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:O14641|rcsb pdb:2REY|rcsb pdb:3CBX|rcsb pdb:3CBY|rcsb pdb:3CBZ|rcsb pdb:3CC0|rcsb pdb:4WIP|rcsb pdb:5LNP|rcsb pdb:5SUY|rcsb pdb:5SUZ|rcsb pdb:6IW3|rcsb pdb:6JCK|reactome:R-HSA-201681|reactome:R-HSA-201688|reactome:R-HSA-2028269|reactome:R-HSA-4086400|reactome:R-HSA-4608870|reactome:R-HSA-4641258|reactome:R-HSA-4641262|reactome:R-HSA-5099900|reactome:R-HSA-5368598|reactome:R-HSA-5663220|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9673324|ensembl:ENSP00000005340|dip:DIP-34433N	sgd:S000001251|reactome:R-SCE-70895|refseq:NP_012078.3|dip:DIP-6475N|ensemblfungi:YHR208W(gene)|ensemblfungi:YHR208W_mRNA(transcript)|go:"GO:0004084"(branched-chain-amino-acid transaminase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0009082"(branched-chain amino acid biosynthetic process)|go:"GO:0009083"(branched-chain amino acid catabolic process)|go:"GO:0009097"(isoleucine biosynthetic process)|go:"GO:0009098"(leucine biosynthetic process)|go:"GO:0009099"(valine biosynthetic process)|go:"GO:0019509"(L-methionine salvage from methylthioadenosine)|go:"GO:0050048"("L-leucine:2-oxoglutarate aminotransferase activity")|go:"GO:0052654"(L-leucine transaminase activity)|go:"GO:0052655"(L-valine transaminase activity)|go:"GO:0052656"(L-isoleucine transaminase activity)|interpro:IPR001544(Aminotransferase, class IV)|interpro:IPR005786(Branched-chain amino acid aminotransferase II)|interpro:IPR018300|interpro:IPR033939|interpro:IPR036038|interpro:IPR043131|interpro:IPR043132	-	-	crc64:E76604F326A7C674	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:2Vdc8oRnT4Mz/j+EXQXrL3AszOc9606	rogid:Rz/okB+egLztOJhwPzzPpl8yXlc559292	intact-crc:C00D664E68C19895|rigid:afXbXqSons1qGvi/zoOlKg8qE0s	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O43765	uniprotkb:P38868	intact:EBI-347996|ensembl:ENSP00000221566|ensembl:ENSP00000503397|ensembl:ENSP00000504495|uniprotkb:Q9BTZ9|intact:EBI-1045243|uniprotkb:Q6FIA9|uniprotkb:D6W610	intact:EBI-24840|uniprotkb:A0A1S0T004|ensemblfungi:YHR180W	psi-mi:sgta_human(display_long)|uniprotkb:SGTA(gene name)|psi-mi:SGTA(display_short)|uniprotkb:SGT(gene name synonym)|uniprotkb:Alpha-SGT(gene name synonym)|uniprotkb:Vpu-binding protein(gene name synonym)|uniprotkb:SGT1(gene name synonym)	psi-mi:yhy0_yeast(display_long)|uniprotkb:YHR180W(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549680|imex:IM-24995-2991	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:4CPG|rcsb pdb:4GOD|rcsb pdb:4GOE|rcsb pdb:4GOF|reactome:R-HSA-9609523|rcsb pdb:2VYI|ensembl:ENSG00000104969(gene)|ensembl:ENST00000221566(transcript)|ensembl:ENST00000676943(transcript)|ensembl:ENST00000677149(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072380"(TRC complex)|go:"GO:0098850"(extrinsic component of synaptic vesicle membrane)|go:"GO:1903070"(negative regulation of ER-associated ubiquitin-dependent protein catabolic process)|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)|go:"GO:1903646"(positive regulation of chaperone-mediated protein folding)|go:"GO:1904288"(BAT3 complex binding)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR032374|mint:O43765|refseq:XP_011526480.1|refseq:NP_003012.1	sgd:S000001223|dip:DIP-4332N|ensemblfungi:YHR180W(gene)|ensemblfungi:YHR180W_mRNA(transcript)|go:"GO:0016021"(integral component of membrane)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:r/Cyj4UJk/cS8QdrbjhTZMPCigI9606	rogid:E7zJN1iVyb08WvBGa7NXcqw4sqw559292	intact-crc:3160EA873AC2F6A8|rigid:xhGW+dGqWWFn41O+2W907wqnGZk	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P38871	uniprotkb:G5E962	intact:EBI-24852|uniprotkb:D3DLD2|ensemblfungi:YHR184W	intact:EBI-11525615|ensembl:ENSP00000328177	psi-mi:ssp1_yeast(display_long)|uniprotkb:SSP1(gene name)|psi-mi:SSP1(display_short)|uniprotkb:YHR184W(locus name)	psi-mi:g5e962_human(display_long)|uniprotkb:hCG_1644200(orf name)|uniprotkb:MAGEA11(gene name)|psi-mi:MAGEA11(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549684|imex:IM-24995-2992	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000001227|refseq:NP_012054.1|dip:DIP-1674N|ensemblfungi:YHR184W(gene)|ensemblfungi:YHR184W_mRNA(transcript)|go:"GO:0005628"(prospore membrane)|go:"GO:0030476"(ascospore wall assembly)|go:"GO:0032120"(ascospore-type prospore membrane formation)|go:"GO:0051301"(cell division)|go:"GO:0070056"(prospore membrane leading edge)	refseq:NP_001011544.1|ensembl:ENSG00000185247(gene)|ensembl:ENST00000333104(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016604"(nuclear body)|interpro:IPR002190(MAGE protein)|interpro:IPR021072|interpro:IPR030099|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899	-	crc64:A199EB4159771A03	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:oYmvoKYf2OWiVyfG4zRm731HTRs559292	rogid:sVB0aA6yibWUx/d2SE+pwpKKgtI9606	intact-crc:2DE96D2A83E78DEE|rigid:V13Cy51tf7GR/hmN/udbtu+VqSk	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P20290-2	uniprotkb:P38879	intact:EBI-1054703|ensembl:ENSP00000338516	intact:EBI-6379|uniprotkb:D3DLE1|ensemblfungi:YHR193C	psi-mi:p20290-2(display_long)|uniprotkb:BTF3b(isoform synonym)|uniprotkb:BTF3(gene name)|psi-mi:BTF3(display_short)|uniprotkb:NACB(gene name synonym)|uniprotkb:RNA polymerase B transcription factor 3(gene name synonym)|uniprotkb:OK/SW-cl.8(orf name)|uniprotkb:Nascent polypeptide-associated complex subunit beta(gene name synonym)	psi-mi:naca_yeast(display_long)|uniprotkb:EGD2(gene name)|psi-mi:EGD2(display_short)|uniprotkb:Alpha-NAC(gene name synonym)|uniprotkb:GAL4 DNA-binding enhancer protein 2(gene name synonym)|uniprotkb:YHR193C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549688|imex:IM-24995-2993	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-1054687(btf3_human)|ensembl:ENSG00000145741(gene)|ensembl:ENST00000335895(transcript)|uniprotkb:P20290-2(isoform-parent)	sgd:S000001236|refseq:NP_012063.3|mint:P38879|dip:DIP-2098N|ensemblfungi:YHR193C(gene)|ensemblfungi:YHR193C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005854"(nascent polypeptide-associated complex)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0070300"(phosphatidic acid binding)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|interpro:IPR002715(Nascent polypeptide-associated complex NAC)|interpro:IPR009060(UBA-like)|interpro:IPR016641(Nascent polypeptide-associated complex, alpha subunit)|interpro:IPR038187|interpro:IPR044034	-	-	crc64:86CE0C4E6194C286	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:nViZ1CRkho2stQQ1ts0kUzwhOO09606	rogid:IjsgR+hZDgTQDvy2Wf8JEX4kF+A559292	intact-crc:FA30FBA9023890FD|rigid:YbdnKjy0+72+LWtuT2IYSXhsw1o	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P39518	uniprotkb:O95197-3	intact:EBI-10082|uniprotkb:D3DLR3|ensemblfungi:YER015W	intact:EBI-11525735|ensembl:ENSP00000440874	psi-mi:lcf2_yeast(display_long)|uniprotkb:YER015W(locus name)|uniprotkb:FAA2(gene name)|psi-mi:FAA2(display_short)|uniprotkb:FAM1(gene name synonym)|uniprotkb:Long-chain acyl-CoA synthetase 2(gene name synonym)|uniprotkb:Fatty acid activator 2(gene name synonym)	psi-mi:o95197-3(display_long)|uniprotkb:RTN3(gene name)|psi-mi:RTN3(display_short)|uniprotkb:ASYIP(gene name synonym)|uniprotkb:Homolog of ASY protein(gene name synonym)|uniprotkb:NSPL2(gene name synonym)|uniprotkb:Neuroendocrine-specific protein-like 2(gene name synonym)|uniprotkb:Neuroendocrine-specific protein-like II(gene name synonym)|uniprotkb:A1(isoform synonym)|uniprotkb:B1(isoform synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549712|imex:IM-24995-2999	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000000817|ensemblfungi:YER015W_mRNA(transcript)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0004467"(long-chain fatty acid-CoA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0015910"(long-chain fatty acid import into peroxisome)|go:"GO:0015916"(fatty-acyl-CoA transport)|go:"GO:0016020"(membrane)|go:"GO:0031956"(medium-chain fatty acid-CoA ligase activity)|go:"GO:0031957"(very long-chain fatty acid-CoA ligase activity)|go:"GO:0042760"(very long-chain fatty acid catabolic process)|go:"GO:0102391"(decanoate-CoA ligase activity)|ensemblfungi:YER015W(gene)|interpro:IPR020845|interpro:IPR000873(AMP-dependent synthetase and ligase)|reactome:R-SCE-75876|refseq:NP_010931.3|dip:DIP-6565N	ensembl:ENSG00000133318(gene)|ensembl:ENST00000537981(transcript)|intact:EBI-740467(isoform-parent)|uniprotkb:O95197-3(isoform-parent)	-	crc64:1E023C18682805BC	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:N0W+wPvCsl01y0k8hJZ156LztOo559292	rogid:+TJnANu85CM52dRZ6s+hYMlUABE9606	intact-crc:F859245E2AF5C6FD|rigid:x+n4ZW7+LM8GqBUsDoGUzPA9Vc8	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P39009	uniprotkb:O14641	intact:EBI-6194|uniprotkb:D6VRP9|ensemblfungi:YDL101C	intact:EBI-740850|ensembl:ENSP00000005340|uniprotkb:Q53XM0|uniprotkb:D3DTN3	psi-mi:dun1_yeast(display_long)|uniprotkb:DUN1(gene name)|psi-mi:DUN1(display_short)|uniprotkb:D2370(orf name)|uniprotkb:YDL101C(locus name)	psi-mi:dvl2_human(display_long)|uniprotkb:DSH homolog 2(gene name synonym)|uniprotkb:DVL2(gene name)|psi-mi:DVL2(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549700|imex:IM-24995-2996	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010182.1|sgd:S000002259|dip:DIP-1772N|reactome:R-SCE-5693565|reactome:R-SCE-69473|reactome:R-SCE-69601|reactome:R-SCE-75035|ensemblfungi:YDL101C(gene)|ensemblfungi:YDL101C_mRNA(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0042770"(signal transduction in response to DNA damage)|go:"GO:0044773"(mitotic DNA damage checkpoint signaling)|go:"GO:0048478"(replication fork protection)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000253(Forkhead-associated)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:2JQJ|rcsb pdb:2JQL	refseq:NP_004413.1|ensembl:ENSG00000004975(gene)|ensembl:ENST00000005340(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005109"(frizzled binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0007507"(heart development)|go:"GO:0016235"(aggresome)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044340"(canonical Wnt signaling pathway involved in regulation of cell proliferation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0150012"(positive regulation of neuron projection arborization)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008341(Dishevelled-2 region)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:O14641|rcsb pdb:2REY|rcsb pdb:3CBX|rcsb pdb:3CBY|rcsb pdb:3CBZ|rcsb pdb:3CC0|rcsb pdb:4WIP|rcsb pdb:5LNP|rcsb pdb:5SUY|rcsb pdb:5SUZ|rcsb pdb:6IW3|rcsb pdb:6JCK|reactome:R-HSA-201681|reactome:R-HSA-201688|reactome:R-HSA-2028269|reactome:R-HSA-4086400|reactome:R-HSA-4608870|reactome:R-HSA-4641258|reactome:R-HSA-4641262|reactome:R-HSA-5099900|reactome:R-HSA-5368598|reactome:R-HSA-5663220|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9673324|ensembl:ENSP00000005340|dip:DIP-34433N	-	crc64:4990F24F024702D7	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:/BmlSDRdkj7efDRuXH/qWpdTv/U559292	rogid:2Vdc8oRnT4Mz/j+EXQXrL3AszOc9606	intact-crc:7ADE05915841CD4E|rigid:8ujev4UxGU6V0MpRNV9N7YEpg+E	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O94972	uniprotkb:P39009	intact:EBI-741602|uniprotkb:Q7Z3E6|uniprotkb:Q8IYF7|uniprotkb:Q8WYF7|intact:EBI-28976055|ensembl:ENSP00000262294|ensembl:ENSP00000376785|uniprotkb:A8K0V9|uniprotkb:A8K8U4|uniprotkb:A8MZ79|uniprotkb:B4DGZ3|uniprotkb:F8WEE6	intact:EBI-6194|uniprotkb:D6VRP9|ensemblfungi:YDL101C	psi-mi:tri37_human(display_long)|uniprotkb:Mulibrey nanism protein(gene name synonym)|uniprotkb:TRIM37(gene name)|psi-mi:TRIM37(display_short)|uniprotkb:KIAA0898(gene name synonym)|uniprotkb:MUL(gene name synonym)|uniprotkb:POB1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 37(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM37(gene name synonym)	psi-mi:dun1_yeast(display_long)|uniprotkb:DUN1(gene name)|psi-mi:DUN1(display_short)|uniprotkb:D2370(orf name)|uniprotkb:YDL101C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549704|imex:IM-24995-2997	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001005207.1|refseq:NP_056109.1|refseq:NP_001307916.1|ensembl:ENSP00000262294|ensembl:ENST00000393065|ensembl:ENSP00000376784|ensembl:ENSP00000376785|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046600"(negative regulation of centriole replication)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070842"(aggresome assembly)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002083(MATH)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR008974(TRAF-like)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR037299|rcsb pdb:3LRQ|reactome:R-HSA-983168|ensembl:ENSG00000108395(gene)|ensembl:ENST00000262294(transcript)|ensembl:ENST00000393066(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005777"(peroxisome)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016235"(aggresome)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0035518"(histone H2A monoubiquitination)|refseq:NP_001307919.1|dip:DIP-34437N	refseq:NP_010182.1|sgd:S000002259|dip:DIP-1772N|reactome:R-SCE-5693565|reactome:R-SCE-69473|reactome:R-SCE-69601|reactome:R-SCE-75035|ensemblfungi:YDL101C(gene)|ensemblfungi:YDL101C_mRNA(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0042770"(signal transduction in response to DNA damage)|go:"GO:0044773"(mitotic DNA damage checkpoint signaling)|go:"GO:0048478"(replication fork protection)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000253(Forkhead-associated)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:2JQJ|rcsb pdb:2JQL	-	-	crc64:4990F24F024702D7	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:y2njeO0MUBrKU9MUvkbo1uZmqkE9606	rogid:/BmlSDRdkj7efDRuXH/qWpdTv/U559292	intact-crc:A8E10B76599358B7|rigid:QR+AyAVHr6gXRTVaED8l3Arm+Xg	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:A0A0C4DGF1	uniprotkb:P39014	intact:EBI-10188476|ensembl:ENSP00000433657	intact:EBI-11507|uniprotkb:D6VVN6|ensemblfungi:YIL046W	psi-mi:a0a0c4dgf1_human(display_long)|uniprotkb:ZBTB32(gene name)|psi-mi:ZBTB32(display_short)	psi-mi:met30_yeast(display_long)|uniprotkb:YIL046W(locus name)|uniprotkb:MET30(gene name)|psi-mi:MET30(display_short)|uniprotkb:Methionine-requiring protein 30(gene name synonym)|uniprotkb:"E3 ubiquitin ligase complex SCF(Met30) subunit MET30"(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549708|imex:IM-24995-2998	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|ensembl:ENSG00000011590(gene)|ensembl:ENST00000481182(transcript)|go:"GO:0042802"(identical protein binding)	ensemblfungi:YIL046W_mRNA(transcript)|ensemblfungi:YIL046W(gene)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009086"(methionine biosynthetic process)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019344"(cysteine biosynthetic process)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043224"(nuclear SCF ubiquitin ligase complex)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0046686"(response to cadmium ion)|interpro:IPR001680(WD40 repeat)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036047|interpro:IPR036322|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|refseq:NP_012218.1|sgd:S000001308|mint:P39014|dip:DIP-1439N	-	-	crc64:5135D4BCA2E1EB97	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:w3k7YT4kw/T+Xi5YBqGHSpHtwMM9606	rogid:B138OcWsG8zW/eFMselD2pFyy5c559292	intact-crc:80DCDC47248E4EFC|rigid:IXhuelB6Pd5JIjAYg+O/Vx1v0tM	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P39518	uniprotkb:P07910-2	intact:EBI-10082|uniprotkb:D3DLR3|ensemblfungi:YER015W	intact:EBI-5280084|ensembl:ENSP00000442816|ensembl:ENSP00000450544|ensembl:ENSP00000450725|ensembl:ENSP00000451176	psi-mi:lcf2_yeast(display_long)|uniprotkb:YER015W(locus name)|uniprotkb:FAA2(gene name)|psi-mi:FAA2(display_short)|uniprotkb:FAM1(gene name synonym)|uniprotkb:Long-chain acyl-CoA synthetase 2(gene name synonym)|uniprotkb:Fatty acid activator 2(gene name synonym)	psi-mi:p07910-2(display_long)|uniprotkb:HNRNPC(gene name)|psi-mi:HNRNPC(display_short)|uniprotkb:HNRPC(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549728|imex:IM-24995-3003	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000000817|ensemblfungi:YER015W_mRNA(transcript)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0004467"(long-chain fatty acid-CoA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0015910"(long-chain fatty acid import into peroxisome)|go:"GO:0015916"(fatty-acyl-CoA transport)|go:"GO:0016020"(membrane)|go:"GO:0031956"(medium-chain fatty acid-CoA ligase activity)|go:"GO:0031957"(very long-chain fatty acid-CoA ligase activity)|go:"GO:0042760"(very long-chain fatty acid catabolic process)|go:"GO:0102391"(decanoate-CoA ligase activity)|ensemblfungi:YER015W(gene)|interpro:IPR020845|interpro:IPR000873(AMP-dependent synthetase and ligase)|reactome:R-SCE-75876|refseq:NP_010931.3|dip:DIP-6565N	uniprotkb:P07910-2(isoform-parent)|intact:EBI-357966(isoform-parent)|ensembl:ENSG00000092199(gene)|ensembl:ENST00000430246(transcript)|ensembl:ENST00000553300(transcript)|ensembl:ENST00000554969(transcript)|ensembl:ENST00000556897(transcript)	-	crc64:1E023C18682805BC	isoform-comment:Contains a phosphoserine at position 107. Contains a phosphoserine at position 108.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:N0W+wPvCsl01y0k8hJZ156LztOo559292	rogid:r7AhGozE3aHdynLr8DrXPRtOuyI9606	intact-crc:68AD1F9190CE685F|rigid:Yh1FrBuSQDLkgkAtbCm/laXsAgQ	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P39518	uniprotkb:P35520	intact:EBI-10082|uniprotkb:D3DLR3|ensemblfungi:YER015W	intact:EBI-740135|uniprotkb:Q99425|uniprotkb:Q9BWC5|uniprotkb:B2R993|uniprotkb:D3DSK4|intact:EBI-14245939|ensembl:ENSP00000344460|ensembl:ENSP00000352643|ensembl:ENSP00000381225|ensembl:ENSP00000381231	psi-mi:lcf2_yeast(display_long)|uniprotkb:YER015W(locus name)|uniprotkb:FAA2(gene name)|psi-mi:FAA2(display_short)|uniprotkb:FAM1(gene name synonym)|uniprotkb:Long-chain acyl-CoA synthetase 2(gene name synonym)|uniprotkb:Fatty acid activator 2(gene name synonym)	psi-mi:cbs_human(display_long)|uniprotkb:CBS(gene name)|psi-mi:CBS(display_short)|uniprotkb:Serine sulfhydrase(gene name synonym)|uniprotkb:Beta-thionase(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549716|imex:IM-24995-3000	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000000817|ensemblfungi:YER015W_mRNA(transcript)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0004467"(long-chain fatty acid-CoA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0015910"(long-chain fatty acid import into peroxisome)|go:"GO:0015916"(fatty-acyl-CoA transport)|go:"GO:0016020"(membrane)|go:"GO:0031956"(medium-chain fatty acid-CoA ligase activity)|go:"GO:0031957"(very long-chain fatty acid-CoA ligase activity)|go:"GO:0042760"(very long-chain fatty acid catabolic process)|go:"GO:0102391"(decanoate-CoA ligase activity)|ensemblfungi:YER015W(gene)|interpro:IPR020845|interpro:IPR000873(AMP-dependent synthetase and ligase)|reactome:R-SCE-75876|refseq:NP_010931.3|dip:DIP-6565N	refseq:NP_000062.1|refseq:NP_001171479.1|refseq:NP_001171480.1|ensembl:ENSG00000160200(gene)|ensembl:ENST00000352178(transcript)|ensembl:ENST00000359624(transcript)|ensembl:ENST00000398158(transcript)|go:"GO:0004122"(cystathionine beta-synthase activity)|ensembl:ENST00000398165(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006535"(cysteine biosynthetic process from serine)|go:"GO:0006563"(L-serine metabolic process)|go:"GO:0006565"(L-serine catabolic process)|go:"GO:0019343"(cysteine biosynthetic process via cystathionine)|go:"GO:0019344"(cysteine biosynthetic process)|go:"GO:0019346"(transsulfuration)|go:"GO:0019448"(L-cysteine catabolic process)|go:"GO:0019825"(oxygen binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0020037"(heme binding)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042262"(DNA protection)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043418"(homocysteine catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0050421"("nitrite reductase (NO-forming) activity")|go:"GO:0050667"(homocysteine metabolic process)|go:"GO:0070025"(carbon monoxide binding)|go:"GO:0070026"(nitric oxide binding)|go:"GO:0070814"(hydrogen sulfide biosynthetic process)|go:"GO:0072341"(modified amino acid binding)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR001216(Cysteine synthase/cystathionine beta-synthase P-phosphate-binding site)|interpro:IPR001926(Pyridoxal phosphate-dependent enzyme, beta subunit)|interpro:IPR005857(Cystathionine beta-synthase)|interpro:IPR036052|mint:P35520|rcsb pdb:1JBQ|rcsb pdb:1M54|rcsb pdb:4COO|rcsb pdb:4L0D|rcsb pdb:4L27|rcsb pdb:4L28|rcsb pdb:4L3V|rcsb pdb:4PCU|rcsb pdb:4UUU|rcsb pdb:5MMS|reactome:R-HSA-1614603|reactome:R-HSA-2408508|refseq:XP_011528079.1|refseq:XP_011528083.1|refseq:XP_011528084.1|refseq:XP_011544396.1|refseq:XP_011544397.1|refseq:XP_011544399.1|refseq:XP_011544400.1|refseq:XP_011544401.1|refseq:NP_001307227.1|refseq:NP_001308002.1|refseq:XP_016883700.1|refseq:XP_016883701.1|refseq:XP_016883702.1|refseq:XP_016883703.1|refseq:XP_016883704.1|refseq:XP_016883705.1|refseq:XP_016883706.1|refseq:XP_016883707.1|refseq:XP_016883978.1|refseq:XP_016883979.1|refseq:XP_016883980.1|refseq:XP_016883981.1	-	crc64:1E023C18682805BC	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:N0W+wPvCsl01y0k8hJZ156LztOo559292	rogid:f9eo0cPOHppVY7Nqejag3YyK18s9606	intact-crc:FF44340E91D5FF5F|rigid:ngkmAHGpWOuDy4j3IBLXuwd8SN4	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P22234	uniprotkb:P39518	intact:EBI-712261|ensembl:ENSP00000264221|ensembl:ENSP00000421096|uniprotkb:E9PDH9|uniprotkb:Q68CQ5|intact:EBI-21352784	intact:EBI-10082|uniprotkb:D3DLR3|ensemblfungi:YER015W	psi-mi:pur6_human(display_long)|uniprotkb:PAICS(gene name)|psi-mi:PAICS(display_short)|uniprotkb:ADE2(gene name synonym)|uniprotkb:AIRC(gene name synonym)|uniprotkb:PAIS(gene name synonym)	psi-mi:lcf2_yeast(display_long)|uniprotkb:YER015W(locus name)|uniprotkb:FAA2(gene name)|psi-mi:FAA2(display_short)|uniprotkb:FAM1(gene name synonym)|uniprotkb:Long-chain acyl-CoA synthetase 2(gene name synonym)|uniprotkb:Fatty acid activator 2(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549720|imex:IM-24995-3001	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000128050(gene)|ensembl:ENST00000264221(transcript)|ensembl:ENST00000512576(transcript)|go:"GO:0004639"(phosphoribosylaminoimidazolesuccinocarboxamide synthase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006189"('de novo' IMP biosynthetic process)|go:"GO:0009113"(purine nucleobase biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043727"(5-amino-4-imidazole carboxylate lyase activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000031("1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase")|interpro:IPR018236|interpro:IPR028923|interpro:IPR033626|mint:P22234|rcsb pdb:2H31|rcsb pdb:6YB8|go:"GO:0004638"(phosphoribosylaminoimidazole carboxylase activity)|rcsb pdb:6YB9|reactome:R-HSA-73817|refseq:NP_001072992.1|refseq:NP_001072993.1|refseq:NP_006443.1	sgd:S000000817|ensemblfungi:YER015W_mRNA(transcript)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0004467"(long-chain fatty acid-CoA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0015910"(long-chain fatty acid import into peroxisome)|go:"GO:0015916"(fatty-acyl-CoA transport)|go:"GO:0016020"(membrane)|go:"GO:0031956"(medium-chain fatty acid-CoA ligase activity)|go:"GO:0031957"(very long-chain fatty acid-CoA ligase activity)|go:"GO:0042760"(very long-chain fatty acid catabolic process)|go:"GO:0102391"(decanoate-CoA ligase activity)|ensemblfungi:YER015W(gene)|interpro:IPR020845|interpro:IPR000873(AMP-dependent synthetase and ligase)|reactome:R-SCE-75876|refseq:NP_010931.3|dip:DIP-6565N	-	-	crc64:1E023C18682805BC	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:aR4Xj14ZQrPiY8cldw5o9AvjkAo9606	rogid:N0W+wPvCsl01y0k8hJZ156LztOo559292	intact-crc:E5ECBFBCFC5C472B|rigid:XQYQO3vd7kUaC61bqXSD4A5ow5k	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P39518	uniprotkb:O96006	intact:EBI-10082|uniprotkb:D3DLR3|ensemblfungi:YER015W	intact:EBI-740037|uniprotkb:Q96BY4|ensembl:ENSP00000370616|ensembl:ENSP00000370620|ensembl:ENSP00000370621|ensembl:ENSP00000498725	psi-mi:lcf2_yeast(display_long)|uniprotkb:YER015W(locus name)|uniprotkb:FAA2(gene name)|psi-mi:FAA2(display_short)|uniprotkb:FAM1(gene name synonym)|uniprotkb:Long-chain acyl-CoA synthetase 2(gene name synonym)|uniprotkb:Fatty acid activator 2(gene name synonym)	psi-mi:zbed1_human(display_long)|uniprotkb:ZBED1(gene name)|psi-mi:ZBED1(display_short)|uniprotkb:ALTE(gene name synonym)|uniprotkb:DREF(gene name synonym)|uniprotkb:KIAA0785(gene name synonym)|uniprotkb:TRAMP(gene name synonym)|uniprotkb:dREF homolog(gene name synonym)|uniprotkb:Putative Ac-like transposable element(gene name synonym)|uniprotkb:DNA replication-related element-binding factor(gene name synonym)|uniprotkb:Zinc finger BED domain-containing protein 1(gene name synonym)|uniprotkb:hDREF(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549724|imex:IM-24995-3002	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000000817|ensemblfungi:YER015W_mRNA(transcript)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0004467"(long-chain fatty acid-CoA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0015910"(long-chain fatty acid import into peroxisome)|go:"GO:0015916"(fatty-acyl-CoA transport)|go:"GO:0016020"(membrane)|go:"GO:0031956"(medium-chain fatty acid-CoA ligase activity)|go:"GO:0031957"(very long-chain fatty acid-CoA ligase activity)|go:"GO:0042760"(very long-chain fatty acid catabolic process)|go:"GO:0102391"(decanoate-CoA ligase activity)|ensemblfungi:YER015W(gene)|interpro:IPR020845|interpro:IPR000873(AMP-dependent synthetase and ligase)|reactome:R-SCE-75876|refseq:NP_010931.3|dip:DIP-6565N	refseq:NP_001164606.1|refseq:NP_001164607.1|refseq:NP_004720.1|ensembl:ENSG00000214717(gene)|ensembl:ENST00000381218(transcript)|ensembl:ENST00000381222(transcript)|ensembl:ENST00000381223(transcript)|ensembl:ENST00000652001(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0031965"(nuclear membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044828"(negative regulation by host of viral genome replication)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0061665"(SUMO ligase activity)|go:"GO:1990466"(protein autosumoylation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003656(Zinc finger, BED-type predicted)|interpro:IPR008906(HAT dimerisation)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR036236|mint:O96006|rcsb pdb:2CT5|reactome:R-HSA-4551638|go:"GO:0005813"(centrosome)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016605"(PML body)	-	crc64:1E023C18682805BC	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:N0W+wPvCsl01y0k8hJZ156LztOo559292	rogid:jl97ZV2Kz5YAmQKktWt/wk7OkRw9606	intact-crc:085A8EA2F92E0683|rigid:sZdkYiOSON76+GVlp5u9S9LSf58	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P39518	uniprotkb:O76083-2	intact:EBI-10082|uniprotkb:D3DLR3|ensemblfungi:YER015W	intact:EBI-11524542|ensembl:ENSP00000335242	psi-mi:lcf2_yeast(display_long)|uniprotkb:YER015W(locus name)|uniprotkb:FAA2(gene name)|psi-mi:FAA2(display_short)|uniprotkb:FAM1(gene name synonym)|uniprotkb:Long-chain acyl-CoA synthetase 2(gene name synonym)|uniprotkb:Fatty acid activator 2(gene name synonym)	psi-mi:o76083-2(display_long)|uniprotkb:PDE9A(gene name)|psi-mi:PDE9A(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549732|imex:IM-24995-3004	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000000817|ensemblfungi:YER015W_mRNA(transcript)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0004467"(long-chain fatty acid-CoA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0015910"(long-chain fatty acid import into peroxisome)|go:"GO:0015916"(fatty-acyl-CoA transport)|go:"GO:0016020"(membrane)|go:"GO:0031956"(medium-chain fatty acid-CoA ligase activity)|go:"GO:0031957"(very long-chain fatty acid-CoA ligase activity)|go:"GO:0042760"(very long-chain fatty acid catabolic process)|go:"GO:0102391"(decanoate-CoA ligase activity)|ensemblfungi:YER015W(gene)|interpro:IPR020845|interpro:IPR000873(AMP-dependent synthetase and ligase)|reactome:R-SCE-75876|refseq:NP_010931.3|dip:DIP-6565N	intact:EBI-742764(isoform-parent)|ensembl:ENSG00000160191(gene)|ensembl:ENST00000335512(transcript)|uniprotkb:O76083-2(isoform-parent)	-	crc64:1E023C18682805BC	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:N0W+wPvCsl01y0k8hJZ156LztOo559292	rogid:nTzgeYGOwTM/7VJUgxSnlnDiCFo9606	intact-crc:132D496AD42A69DA|rigid:Dk/8xP4LKaNsYTJltvWK8HDs5Js	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O00635	uniprotkb:P39518	intact:EBI-2130415|uniprotkb:B2R862|ensembl:ENSP00000349596	intact:EBI-10082|uniprotkb:D3DLR3|ensemblfungi:YER015W	psi-mi:tri38_human(display_long)|uniprotkb:TRIM38(gene name)|psi-mi:TRIM38(display_short)|uniprotkb:RNF15(gene name synonym)|uniprotkb:RORET(gene name synonym)|uniprotkb:RING finger protein 15(gene name synonym)|uniprotkb:Zinc finger protein RoRet(gene name synonym)|uniprotkb:Tripartite motif-containing protein 38(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM38(gene name synonym)	psi-mi:lcf2_yeast(display_long)|uniprotkb:YER015W(locus name)|uniprotkb:FAA2(gene name)|psi-mi:FAA2(display_short)|uniprotkb:FAM1(gene name synonym)|uniprotkb:Long-chain acyl-CoA synthetase 2(gene name synonym)|uniprotkb:Fatty acid activator 2(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549736|imex:IM-24995-3005	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006346.1|refseq:XP_005248856.1|refseq:XP_005248857.1|ensembl:ENSG00000112343(gene)|ensembl:ENST00000357085(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046598"(positive regulation of viral entry into host cell)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR035790|interpro:IPR043136|reactome:R-HSA-877300	sgd:S000000817|ensemblfungi:YER015W_mRNA(transcript)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0004467"(long-chain fatty acid-CoA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0015910"(long-chain fatty acid import into peroxisome)|go:"GO:0015916"(fatty-acyl-CoA transport)|go:"GO:0016020"(membrane)|go:"GO:0031956"(medium-chain fatty acid-CoA ligase activity)|go:"GO:0031957"(very long-chain fatty acid-CoA ligase activity)|go:"GO:0042760"(very long-chain fatty acid catabolic process)|go:"GO:0102391"(decanoate-CoA ligase activity)|ensemblfungi:YER015W(gene)|interpro:IPR020845|interpro:IPR000873(AMP-dependent synthetase and ligase)|reactome:R-SCE-75876|refseq:NP_010931.3|dip:DIP-6565N	-	-	crc64:1E023C18682805BC	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Zh4X/6v/qKZlDkMV6hhn7OsvPnQ9606	rogid:N0W+wPvCsl01y0k8hJZ156LztOo559292	intact-crc:11D50CE36237088D|rigid:DYAXS5I8rCUG/nH272qtRBbq/p8	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P37198	uniprotkb:P40014	intact:EBI-347978|intact:EBI-28983799|ensembl:ENSP00000305503|ensembl:ENSP00000407331|ensembl:ENSP00000471191|ensembl:ENSP00000473192|uniprotkb:Q6GTM2|uniprotkb:Q503A4|uniprotkb:Q96C43|uniprotkb:Q9NSL1|uniprotkb:B3KWU5	intact:EBI-22458|uniprotkb:D3DLR6|ensemblfungi:YER018C	psi-mi:nup62_human(display_long)|uniprotkb:NUP62(gene name)|psi-mi:NUP62(display_short)|uniprotkb:62 kDa nucleoporin(gene name synonym)|uniprotkb:Nucleoporin Nup62(gene name synonym)	psi-mi:spc25_yeast(display_long)|uniprotkb:YER018C(locus name)|uniprotkb:SPC25(gene name)|psi-mi:SPC25(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549764|imex:IM-24995-3012	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_714941.1|ensembl:ENSG00000213024(gene)|ensembl:ENST00000352066(transcript)|ensembl:ENST00000422090(transcript)|ensembl:ENST00000596217(transcript)|ensembl:ENST00000597029(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005642"(annulate lamellae)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007100"(mitotic centrosome separation)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007569"(cell aging)|go:"GO:0008219"(cell death)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0003682"(chromatin binding)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0019894"(kinesin binding)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042306"(regulation of protein import into nucleus)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043069"(negative regulation of programmed cell death)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045742"(positive regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046578"(regulation of Ras protein signal transduction)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0046601"(positive regulation of centriole replication)|go:"GO:0051028"(mRNA transport)|go:"GO:0051425"(PTB domain binding)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0072686"(mitotic spindle)|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|go:"GO:0090543"(Flemming body)|go:"GO:0098534"(centriole assembly)|go:"GO:1903438"(positive regulation of mitotic cytokinetic process)|go:"GO:1904781"(positive regulation of protein localization to centrosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR007758(Nucleoporin, Nsp1-like, C-terminal)|interpro:IPR026010|interpro:IPR033072|mint:P37198|rcsb pdb:2H4D|rcsb pdb:5IJN|rcsb pdb:5IJO|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|refseq:NP_714940.1|refseq:NP_001180286.1|refseq:NP_036478.2|refseq:NP_057637.2|ensembl:ENSP00000305503|ensembl:ENSP00000407331|ensembl:ENSP00000471191|ensembl:ENSP00000473192|dip:DIP-29749N	refseq:NP_010934.3|sgd:S000000820|dip:DIP-2990N|mint:P40014|ensemblfungi:YER018C(gene)|ensemblfungi:YER018C_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0051301"(cell division)|go:"GO:0098653"(centromere clustering)|interpro:IPR038066|rcsb pdb:2FTX|rcsb pdb:2FV4|rcsb pdb:4GEQ|rcsb pdb:5T6J|rcsb pdb:5TCS|rcsb pdb:5TD8|rcsb pdb:7KDF	-	-	crc64:1BED6CCFF330A5D8	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:v7mvKvTtVEnLMwcpUZIcdAzge009606	rogid:i5gKRZA7GAjnCVzuX/qP8YmpQRA559292	intact-crc:D6CB3107C0EB119B|rigid:oeFv3L40gCjAcSxUtWPfYIyIC0Q	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P50222	uniprotkb:P39962	intact:EBI-748397|uniprotkb:O75263|ensembl:ENSP00000262041|uniprotkb:Q9UPL6|uniprotkb:B2R8I7|intact:EBI-10172134|intact:EBI-11522964|intact:EBI-11750003|intact:EBI-12702266|uniprotkb:A4D127	intact:EBI-4740|uniprotkb:D3DM29|ensemblfungi:YER123W	psi-mi:meox2_human(display_long)|uniprotkb:Mesenchyme homeobox 2(gene name synonym)|uniprotkb:Growth arrest-specific homeobox(gene name synonym)|uniprotkb:MEOX2(gene name)|psi-mi:MEOX2(display_short)|uniprotkb:GAX(gene name synonym)|uniprotkb:MOX2(gene name synonym)	psi-mi:kc13_yeast(display_long)|uniprotkb:YCK3(gene name)|psi-mi:YCK3(display_short)|uniprotkb:CKI3(gene name synonym)|uniprotkb:YER123W(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549760|imex:IM-24995-3011	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000106511(gene)|ensembl:ENST00000262041(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0001757"(somite specification)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007275"(multicellular organism development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008015"(blood circulation)|go:"GO:0016607"(nuclear speck)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060173"(limb development)|go:"GO:0061053"(somite development)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR042634|refseq:NP_005915.2	refseq:NP_011049.2|sgd:S000000925|dip:DIP-6331N|mint:P39962|ensemblfungi:YER123W(gene)|ensemblfungi:YER123W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006897"(endocytosis)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0031965"(nuclear membrane)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)	-	-	crc64:FD4BBA311D0CD805	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2017/05/26	rogid:fMv0ruKikzQ3MC0PBvJ3pOAjW+U9606	rogid:RIRZO4asqxXqkm1L6tHZtWI/rQQ559292	intact-crc:C4A3B351E37C26AD|rigid:cwsTXbnKusLLEFlzzX/sy7fgHR4	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P39729	uniprotkb:Q08379	intact:EBI-20651|uniprotkb:D6VPI1|ensemblfungi:YAL036C	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	psi-mi:rbg1_yeast(display_long)|uniprotkb:GTP-binding protein RBG1(gene name synonym)|uniprotkb:YAL036C(locus name)|uniprotkb:RBG1(gene name)|psi-mi:RBG1(display_short)|uniprotkb:FUN11(gene name synonym)|uniprotkb:Genetically interacts with ribosomal genes protein 1(gene name synonym)	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549756|imex:IM-24995-3010	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009364.1|sgd:S000000034|ensemblfungi:YAL036C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005844"(polysome)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:1903833"(positive regulation of cellular response to amino acid starvation)|interpro:IPR004095(TGS)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006073(GTP1/OBG)|interpro:IPR006074(GTP1/OBG, conserved site)|interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|interpro:IPR012676(TGS-like)|interpro:IPR027417|interpro:IPR031167|interpro:IPR031662|rcsb pdb:4A9A|ensemblfungi:YAL036C(gene)|dip:DIP-1750N|mint:P39729	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N	-	crc64:D25C6C732B462A6B	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2017/05/26	rogid:PYUgCeuX5pWutVTDI01InMby/OE559292	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	intact-crc:C9B1CC07F654B5DB|rigid:NPLA9nGy9IG1IB+lxlh4nLZNLCU	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O14777	uniprotkb:P39518	intact:EBI-715849|uniprotkb:Q6PJX2|ensembl:ENSP00000261597	intact:EBI-10082|uniprotkb:D3DLR3|ensemblfungi:YER015W	psi-mi:ndc80_human(display_long)|uniprotkb:Kinetochore protein Hec1(gene name synonym)|uniprotkb:Kinetochore-associated protein 2(gene name synonym)|uniprotkb:Highly expressed in cancer protein(gene name synonym)|uniprotkb:Retinoblastoma-associated protein HEC(gene name synonym)|uniprotkb:NDC80(gene name)|psi-mi:NDC80(display_short)|uniprotkb:HEC(gene name synonym)|uniprotkb:KNTC2(gene name synonym)|uniprotkb:HEC1(gene name synonym)	psi-mi:lcf2_yeast(display_long)|uniprotkb:YER015W(locus name)|uniprotkb:FAA2(gene name)|psi-mi:FAA2(display_short)|uniprotkb:FAM1(gene name synonym)|uniprotkb:Long-chain acyl-CoA synthetase 2(gene name synonym)|uniprotkb:Fatty acid activator 2(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549740|imex:IM-24995-3006	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006092.1|ensembl:ENSG00000080986(gene)|ensembl:ENST00000261597(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000940"(outer kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008608"(attachment of spindle microtubules to kinetochore)|go:"GO:0016020"(membrane)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051298"(centrosome duplication)|go:"GO:0051301"(cell division)|go:"GO:0051310"(metaphase plate congression)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051383"(kinetochore organization)|go:"GO:0090267"(positive regulation of mitotic cell cycle spindle assembly checkpoint)|go:"GO:1905342"(positive regulation of protein localization to kinetochore)|interpro:IPR005550(HEC/Ndc80p)|interpro:IPR038273|interpro:IPR040967|mint:O14777|rcsb pdb:2IGP|rcsb pdb:2VE7|rcsb pdb:3IZ0|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|dip:DIP-35100N	sgd:S000000817|ensemblfungi:YER015W_mRNA(transcript)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0004467"(long-chain fatty acid-CoA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0015910"(long-chain fatty acid import into peroxisome)|go:"GO:0015916"(fatty-acyl-CoA transport)|go:"GO:0016020"(membrane)|go:"GO:0031956"(medium-chain fatty acid-CoA ligase activity)|go:"GO:0031957"(very long-chain fatty acid-CoA ligase activity)|go:"GO:0042760"(very long-chain fatty acid catabolic process)|go:"GO:0102391"(decanoate-CoA ligase activity)|ensemblfungi:YER015W(gene)|interpro:IPR020845|interpro:IPR000873(AMP-dependent synthetase and ligase)|reactome:R-SCE-75876|refseq:NP_010931.3|dip:DIP-6565N	-	-	crc64:1E023C18682805BC	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:5OsXbZPvJTMWPepp7M+AXlJUQ649606	rogid:N0W+wPvCsl01y0k8hJZ156LztOo559292	intact-crc:36ED28137A7C9163|rigid:1gnk8ybQrgiQ3DaBb+Wo4SQgyjc	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P39682	uniprotkb:O14641	intact:EBI-612|uniprotkb:D6VZC9|uniprotkb:E9P8Z1|ensemblfungi:YML046W	intact:EBI-740850|ensembl:ENSP00000005340|uniprotkb:Q53XM0|uniprotkb:D3DTN3	psi-mi:prp39_yeast(display_long)|uniprotkb:YM9827.06(orf name)|uniprotkb:YML046W(locus name)|uniprotkb:PRP39(gene name)|psi-mi:PRP39(display_short)	psi-mi:dvl2_human(display_long)|uniprotkb:DSH homolog 2(gene name synonym)|uniprotkb:DVL2(gene name)|psi-mi:DVL2(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549748|imex:IM-24995-3008	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013667.1|sgd:S000004509|dip:DIP-812N|mint:P39682|ensemblfungi:YML046W(gene)|ensemblfungi:YML046W_mRNA(transcript)|go:"GO:0000243"(commitment complex)|go:"GO:0000395"(mRNA 5'-splice site recognition)|go:"GO:0005685"(U1 snRNP)|go:"GO:0071004"(U2-type prespliceosome)|interpro:IPR003107(RNA-processing protein, HAT helix)|interpro:IPR011990(Tetratricopeptide-like helical)|rcsb pdb:5ZWN|rcsb pdb:6G90|rcsb pdb:6N7P|rcsb pdb:6N7R|rcsb pdb:6N7X	refseq:NP_004413.1|ensembl:ENSG00000004975(gene)|ensembl:ENST00000005340(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005109"(frizzled binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0007507"(heart development)|go:"GO:0016235"(aggresome)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044340"(canonical Wnt signaling pathway involved in regulation of cell proliferation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0150012"(positive regulation of neuron projection arborization)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008341(Dishevelled-2 region)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:O14641|rcsb pdb:2REY|rcsb pdb:3CBX|rcsb pdb:3CBY|rcsb pdb:3CBZ|rcsb pdb:3CC0|rcsb pdb:4WIP|rcsb pdb:5LNP|rcsb pdb:5SUY|rcsb pdb:5SUZ|rcsb pdb:6IW3|rcsb pdb:6JCK|reactome:R-HSA-201681|reactome:R-HSA-201688|reactome:R-HSA-2028269|reactome:R-HSA-4086400|reactome:R-HSA-4608870|reactome:R-HSA-4641258|reactome:R-HSA-4641262|reactome:R-HSA-5099900|reactome:R-HSA-5368598|reactome:R-HSA-5663220|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9673324|ensembl:ENSP00000005340|dip:DIP-34433N	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:urVLzQFKnYT1bYOs3yRd9dd7lMk559292	rogid:2Vdc8oRnT4Mz/j+EXQXrL3AszOc9606	intact-crc:BC4DC8A5B63538FE|rigid:Pfvm9smdLdGgF8hkioD1aRn7hOQ	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P39682	uniprotkb:P31249	intact:EBI-612|uniprotkb:D6VZC9|uniprotkb:E9P8Z1|ensemblfungi:YML046W	intact:EBI-3957655|ensembl:ENSP00000249440|ensembl:ENSP00000386498|ensembl:ENSP00000507129|uniprotkb:Q99955|uniprotkb:Q9BSC5	psi-mi:prp39_yeast(display_long)|uniprotkb:YM9827.06(orf name)|uniprotkb:YML046W(locus name)|uniprotkb:PRP39(gene name)|psi-mi:PRP39(display_short)	psi-mi:hxd3_human(display_long)|uniprotkb:HOXD3(gene name)|psi-mi:HOXD3(display_short)|uniprotkb:HOX1D(gene name synonym)|uniprotkb:HOX4A(gene name synonym)|uniprotkb:Homeobox protein Hox-4A(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549744|imex:IM-24995-3007	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013667.1|sgd:S000004509|dip:DIP-812N|mint:P39682|ensemblfungi:YML046W(gene)|ensemblfungi:YML046W_mRNA(transcript)|go:"GO:0000243"(commitment complex)|go:"GO:0000395"(mRNA 5'-splice site recognition)|go:"GO:0005685"(U1 snRNP)|go:"GO:0071004"(U2-type prespliceosome)|interpro:IPR003107(RNA-processing protein, HAT helix)|interpro:IPR011990(Tetratricopeptide-like helical)|rcsb pdb:5ZWN|rcsb pdb:6G90|rcsb pdb:6N7P|rcsb pdb:6N7R|rcsb pdb:6N7X	ensembl:ENSG00000128652(gene)|ensembl:ENST00000249440(transcript)|ensembl:ENST00000410016(transcript)|ensembl:ENST00000683222(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016235"(aggresome)|go:"GO:0016604"(nuclear body)|go:"GO:0030878"(thyroid gland development)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0051216"(cartilage development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001827(Homeobox protein, antennapedia type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR025281|reactome:R-HSA-5617472|refseq:XP_011509367.1|refseq:XP_011509368.1|refseq:NP_008829.3|refseq:XP_005246566.1|refseq:XP_005246567.1|refseq:XP_005246568.1|refseq:XP_005246570.1|refseq:XP_006712540.1	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:urVLzQFKnYT1bYOs3yRd9dd7lMk559292	rogid:6egSlcCWXDnEWbOnwNGI/0ZxBM49606	intact-crc:953F4DEE34C0E03C|rigid:lHvJJ2aYGlXmwZMSAt4SgWVhhbU	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P39724	uniprotkb:O76003	intact:EBI-2343154|uniprotkb:D6VPH0|ensemblfungi:YAL046C	intact:EBI-374781|uniprotkb:Q96CE0|uniprotkb:Q9P1B0|uniprotkb:Q9P1B1|uniprotkb:B3KMP7|uniprotkb:B3KMQ5|uniprotkb:Q5JV01|ensembl:ENSP00000330836|ensembl:ENSP00000357633|ensembl:ENSP00000435445|uniprotkb:D3DRG2	psi-mi:bol3_yeast(display_long)|uniprotkb:BOL3(gene name)|psi-mi:BOL3(display_short)|uniprotkb:AIM1(gene name synonym)|uniprotkb:Altered inheritance of mitochondria protein 1(gene name synonym)|uniprotkb:YAL046C(locus name)	psi-mi:glrx3_human(display_long)|uniprotkb:GLRX3(gene name)|psi-mi:GLRX3(display_short)|uniprotkb:Thioredoxin-like protein 2(gene name synonym)|uniprotkb:PKC-interacting cousin of thioredoxin(gene name synonym)|uniprotkb:PKC-theta-interacting protein(gene name synonym)|uniprotkb:PICOT(gene name synonym)|uniprotkb:HUSSY-22(orf name)|uniprotkb:TXNL2(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549752|imex:IM-24995-3009	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009353.1|sgd:S000000044|interpro:IPR002634(BolA-like protein)|interpro:IPR036065|mint:P39724|ensemblfungi:YAL046C(gene)|ensemblfungi:YAL046C_mRNA(transcript)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0106035"(protein maturation by [4Fe-4S] cluster transfer)	ensembl:ENSG00000108010(gene)|ensembl:ENST00000331244(transcript)|ensembl:ENST00000368644(transcript)|ensembl:ENST00000481034(transcript)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0003723"(RNA binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0030018"(Z disc)|go:"GO:0030425"(dendrite)|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051536"(iron-sulfur cluster binding)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|go:"GO:0097573"(glutathione oxidoreductase activity)|interpro:IPR002109(Glutaredoxin)|interpro:IPR004480(Glutaredoxin-related protein)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR033658|interpro:IPR036249|mint:O76003|rcsb pdb:2DIY|rcsb pdb:2WZ9|rcsb pdb:2YAN|rcsb pdb:3ZYW|reactome:R-HSA-917937|refseq:NP_001186797.1|refseq:NP_006532.2|dip:DIP-31306N	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:MLrW6Iu4YKXf87O1cyx5bY03VdE559292	rogid:iKUSt6zbNzzXSKvW+vXMq3hKsEM9606	intact-crc:4ED38E7F22B5B8A5|rigid:65CXs8AEkDwCIAvSRuAP0q6t2ck	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P40075	uniprotkb:O15209	intact:EBI-16735|ensemblfungi:YER120W|uniprotkb:D3DM26	intact:EBI-723574|uniprotkb:Q5HYV4|uniprotkb:Q5STL0|uniprotkb:Q5STR7|uniprotkb:Q8WV82|ensembl:ENSP00000372683|ensembl:ENSP00000388191|ensembl:ENSP00000393514|ensembl:ENSP00000396292|ensembl:ENSP00000404403|ensembl:ENSP00000407545|uniprotkb:B0V007	psi-mi:scs2_yeast(display_long)|uniprotkb:YER120W(locus name)|uniprotkb:SCS2(gene name)|psi-mi:SCS2(display_short)|uniprotkb:VAP homolog 1(gene name synonym)|uniprotkb:Choline sensitivity suppressor protein 2(gene name synonym)	psi-mi:zbt22_human(display_long)|uniprotkb:Zinc finger protein 297(gene name synonym)|uniprotkb:Protein BING1(gene name synonym)|uniprotkb:Zinc finger and BTB domain-containing protein 22A(gene name synonym)|uniprotkb:ZBTB22(gene name)|psi-mi:ZBTB22(display_short)|uniprotkb:BING1(gene name synonym)|uniprotkb:ZBTB22A(gene name synonym)|uniprotkb:ZNF297(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549784|imex:IM-24995-3017	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011046.3|ensemblfungi:YER120W(gene)|ensemblfungi:YER120W_mRNA(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042308"(negative regulation of protein import into nucleus)|go:"GO:0048309"(endoplasmic reticulum inheritance)|go:"GO:0060304"(regulation of phosphatidylinositol dephosphorylation)|go:"GO:0005886"(plasma membrane)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0061163"(endoplasmic reticulum polarization)|go:"GO:0006348"|go:"GO:0061817"(endoplasmic reticulum-plasma membrane tethering)|go:"GO:0008654"(phospholipid biosynthetic process)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032377"(regulation of intracellular lipid transport)|go:"GO:0033149"(FFAT motif binding)|go:"GO:0071561"(nucleus-vacuole junction)|go:"GO:0090158"(endoplasmic reticulum membrane organization)|interpro:IPR000535(Major sperm protein)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016763(Vesicle-associated membrane protein)|rcsb pdb:6LP4|reactome:R-SCE-6798695|reactome:R-SCE-9609523|sgd:S000000922|dip:DIP-2272N|mint:P40075	refseq:NP_001138810.1|refseq:NP_005444.4|ensembl:ENSG00000206280(gene)|ensembl:ENSG00000227780(gene)|ensembl:ENSG00000229253(gene)|ensembl:ENSG00000236104(gene)|ensembl:ENSG00000237056(gene)|ensembl:ENST00000418724(transcript)|ensembl:ENST00000431845(transcript)|ensembl:ENST00000445320(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR029833|interpro:IPR036236|ensembl:ENST00000383196(transcript)|ensembl:ENST00000416097(transcript)|ensembl:ENST00000418540(transcript)|dip:DIP-62047N	-	crc64:45390E24E31D392E	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:P5Pirj7wRxTi5bdoNs8lCzzTNPI559292	rogid:/u3Is9uJ0nS5Ru7xZKg4MqF6dzE9606	intact-crc:24136E86FFDAFB71|rigid:Pxr8b2kLMXZ4AHOUGCSBcjtKp3M	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P19012	uniprotkb:P40045	intact:EBI-739566|uniprotkb:Q53XV8|uniprotkb:Q9BUG4|uniprotkb:B3KQY1|uniprotkb:B3KRA2|uniprotkb:E0CX14|ensembl:ENSP00000254043|ensembl:ENSP00000377546	intact:EBI-22573|uniprotkb:D3DLX6|ensemblfungi:YER071C	psi-mi:k1c15_human(display_long)|uniprotkb:KRT15(gene name)|psi-mi:KRT15(display_short)|uniprotkb:KRTB(gene name synonym)|uniprotkb:Cytokeratin-15(gene name synonym)|uniprotkb:Keratin-15(gene name synonym)	psi-mi:tda2_yeast(display_long)|uniprotkb:YER071C(locus name)|uniprotkb:TDA2(gene name)|psi-mi:TDA2(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549780|imex:IM-24995-3016	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002266.2|ensembl:ENSG00000171346(gene)|ensembl:ENST00000254043(transcript)|ensembl:ENST00000393976(transcript)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0008544"(epidermis development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097110"(scaffold protein binding)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR039008|mint:P19012|reactome:R-HSA-6805567|reactome:R-HSA-6809371	refseq:NP_010994.3|sgd:S000000873|dip:DIP-4134N|mint:P40045|ensemblfungi:YER071C(gene)|ensemblfungi:YER071C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0030479"(actin cortical patch)|go:"GO:0030837"(negative regulation of actin filament polymerization)|go:"GO:0043332"(mating projection tip)|go:"GO:0110131"(Aim21-Tda2 complex)|interpro:IPR005334(Tctex-1)|interpro:IPR038586|rcsb pdb:5VKY	-	-	crc64:2F5CD27AF0C9AFE3	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:WrZQBYQvrWcfrR5ojWXrXp6spPE9606	rogid:xlo2Qkef4nrF1u7WQ+p7SjixmFs559292	intact-crc:57ED1839383FA9C0|rigid:Bj3x2ESld+NXJ5RwNeaNYdaHqco	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P40014	uniprotkb:P19012	intact:EBI-22458|uniprotkb:D3DLR6|ensemblfungi:YER018C	intact:EBI-739566|uniprotkb:Q53XV8|uniprotkb:Q9BUG4|uniprotkb:B3KQY1|uniprotkb:B3KRA2|uniprotkb:E0CX14|ensembl:ENSP00000254043|ensembl:ENSP00000377546	psi-mi:spc25_yeast(display_long)|uniprotkb:YER018C(locus name)|uniprotkb:SPC25(gene name)|psi-mi:SPC25(display_short)	psi-mi:k1c15_human(display_long)|uniprotkb:KRT15(gene name)|psi-mi:KRT15(display_short)|uniprotkb:KRTB(gene name synonym)|uniprotkb:Cytokeratin-15(gene name synonym)|uniprotkb:Keratin-15(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549768|imex:IM-24995-3013	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010934.3|sgd:S000000820|dip:DIP-2990N|mint:P40014|ensemblfungi:YER018C(gene)|ensemblfungi:YER018C_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0051301"(cell division)|go:"GO:0098653"(centromere clustering)|interpro:IPR038066|rcsb pdb:2FTX|rcsb pdb:2FV4|rcsb pdb:4GEQ|rcsb pdb:5T6J|rcsb pdb:5TCS|rcsb pdb:5TD8|rcsb pdb:7KDF	refseq:NP_002266.2|ensembl:ENSG00000171346(gene)|ensembl:ENST00000254043(transcript)|ensembl:ENST00000393976(transcript)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0008544"(epidermis development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097110"(scaffold protein binding)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR039008|mint:P19012|reactome:R-HSA-6805567|reactome:R-HSA-6809371	-	crc64:1BED6CCFF330A5D8	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:i5gKRZA7GAjnCVzuX/qP8YmpQRA559292	rogid:WrZQBYQvrWcfrR5ojWXrXp6spPE9606	intact-crc:BC9EE780D2DA9D70|rigid:oUgxdUwOfZcG73bJAbMTmS43eWU	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P40014	uniprotkb:Q08379	intact:EBI-22458|uniprotkb:D3DLR6|ensemblfungi:YER018C	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	psi-mi:spc25_yeast(display_long)|uniprotkb:YER018C(locus name)|uniprotkb:SPC25(gene name)|psi-mi:SPC25(display_short)	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549772|imex:IM-24995-3014	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010934.3|sgd:S000000820|dip:DIP-2990N|mint:P40014|ensemblfungi:YER018C(gene)|ensemblfungi:YER018C_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0051301"(cell division)|go:"GO:0098653"(centromere clustering)|interpro:IPR038066|rcsb pdb:2FTX|rcsb pdb:2FV4|rcsb pdb:4GEQ|rcsb pdb:5T6J|rcsb pdb:5TCS|rcsb pdb:5TD8|rcsb pdb:7KDF	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N	-	crc64:1BED6CCFF330A5D8	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2017/05/26	rogid:i5gKRZA7GAjnCVzuX/qP8YmpQRA559292	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	intact-crc:AEA3E62B0D3189B7|rigid:eJgt/sLTHxO0GUAEoQCNeFv/uvk	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P40045	uniprotkb:O76081-6	intact:EBI-22573|uniprotkb:D3DLX6|ensemblfungi:YER071C	intact:EBI-10178530|ensembl:ENSP00000276500	psi-mi:tda2_yeast(display_long)|uniprotkb:YER071C(locus name)|uniprotkb:TDA2(gene name)|psi-mi:TDA2(display_short)	psi-mi:o76081-6(display_long)|uniprotkb:RGS20(gene name)|psi-mi:RGS20(display_short)|uniprotkb:Gz-selective GTPase-activating protein(gene name synonym)|uniprotkb:RGSZ1(gene name synonym)|uniprotkb:Regulator of G-protein signaling Z1(gene name synonym)|uniprotkb:Regulator of Gz-selective protein signaling 1(gene name synonym)|uniprotkb:ZGAP1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549776|imex:IM-24995-3015	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010994.3|sgd:S000000873|dip:DIP-4134N|mint:P40045|ensemblfungi:YER071C(gene)|ensemblfungi:YER071C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0030479"(actin cortical patch)|go:"GO:0030837"(negative regulation of actin filament polymerization)|go:"GO:0043332"(mating projection tip)|go:"GO:0110131"(Aim21-Tda2 complex)|interpro:IPR005334(Tctex-1)|interpro:IPR038586|rcsb pdb:5VKY	intact:EBI-1052678(isoform-parent)|uniprotkb:O76081-6(isoform-parent)|ensembl:ENSG00000147509(gene)|ensembl:ENST00000276500(transcript)	-	crc64:2F5CD27AF0C9AFE3	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:xlo2Qkef4nrF1u7WQ+p7SjixmFs559292	rogid:5ddWx+4uSAxIhugOqlfdCIOD8sM9606	intact-crc:24E082396E6127D1|rigid:Se6nOEof1Yp+d3QlMTxO8dcz+O4	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O14641	uniprotkb:P40078	intact:EBI-740850|ensembl:ENSP00000005340|uniprotkb:Q53XM0|uniprotkb:D3DTN3	intact:EBI-22681|uniprotkb:D3DM32|ensemblfungi:YER126C	psi-mi:dvl2_human(display_long)|uniprotkb:DSH homolog 2(gene name synonym)|uniprotkb:DVL2(gene name)|psi-mi:DVL2(display_short)	psi-mi:nsa2_yeast(display_long)|uniprotkb:YER126C(locus name)|uniprotkb:SYGP-ORF47(orf name)|uniprotkb:NSA2(gene name)|psi-mi:NSA2(display_short)|uniprotkb:NOP7-associated protein 2(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549788|imex:IM-24995-3018	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004413.1|ensembl:ENSG00000004975(gene)|ensembl:ENST00000005340(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005109"(frizzled binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0007507"(heart development)|go:"GO:0016235"(aggresome)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044340"(canonical Wnt signaling pathway involved in regulation of cell proliferation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0150012"(positive regulation of neuron projection arborization)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008341(Dishevelled-2 region)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:O14641|rcsb pdb:2REY|rcsb pdb:3CBX|rcsb pdb:3CBY|rcsb pdb:3CBZ|rcsb pdb:3CC0|rcsb pdb:4WIP|rcsb pdb:5LNP|rcsb pdb:5SUY|rcsb pdb:5SUZ|rcsb pdb:6IW3|rcsb pdb:6JCK|reactome:R-HSA-201681|reactome:R-HSA-201688|reactome:R-HSA-2028269|reactome:R-HSA-4086400|reactome:R-HSA-4608870|reactome:R-HSA-4641258|reactome:R-HSA-4641262|reactome:R-HSA-5099900|reactome:R-HSA-5368598|reactome:R-HSA-5663220|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9673324|ensembl:ENSP00000005340|dip:DIP-34433N	refseq:NP_011052.1|sgd:S000000928|dip:DIP-1892N|mint:P40078|ensemblfungi:YER126C(gene)|ensemblfungi:YER126C_mRNA(transcript)|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000466"("maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0042273"(ribosomal large subunit biogenesis)|interpro:IPR022309|interpro:IPR039411|rcsb pdb:3JCT|rcsb pdb:4WJV|rcsb pdb:6ELZ|rcsb pdb:6EM1|rcsb pdb:6EM5|rcsb pdb:6FT6|rcsb pdb:6M62|rcsb pdb:6N8J|rcsb pdb:7BT6|rcsb pdb:7BTB	-	-	crc64:545C8B4250BCB0C9	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:2Vdc8oRnT4Mz/j+EXQXrL3AszOc9606	rogid:ru6dofBbaVkHM+0tunQ4n36y98M559292	intact-crc:387BB5A992AF7250|rigid:tWCDx+BU2anm9C6WOZ01tGn0vL8	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P14373	uniprotkb:P40302	intact:EBI-719493|uniprotkb:A2BE15|uniprotkb:Q5RJA8|uniprotkb:Q5ST26|uniprotkb:Q6LA73|uniprotkb:Q6NXR9|uniprotkb:Q9BZY6|uniprotkb:Q9UJL3|ensembl:ENSP00000383555|ensembl:ENSP00000392787|ensembl:ENSP00000405229|ensembl:ENSP00000414793|ensembl:ENSP00000366404	intact:EBI-13955|ensemblfungi:YMR314W|uniprotkb:D6W0E1	psi-mi:tri27_human(display_long)|uniprotkb:TRIM27(gene name)|psi-mi:TRIM27(display_short)|uniprotkb:RNF76(gene name synonym)|uniprotkb:RFP(gene name synonym)|uniprotkb:Ret finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 27(gene name synonym)|uniprotkb:RING finger protein 76(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM27(gene name synonym)	psi-mi:psa6_yeast(display_long)|uniprotkb:PRE5(gene name)|psi-mi:PRE5(display_short)|uniprotkb:YMR314W(locus name)|uniprotkb:YM9924.06(orf name)|uniprotkb:Proteasome component PRE5(gene name synonym)|uniprotkb:Macropain subunit PRE5(gene name synonym)|uniprotkb:Proteinase YSCE subunit PRE5(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit PRE5(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549824|imex:IM-24995-3027	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006501.1|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0090281"(negative regulation of calcium ion import)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR020457|interpro:IPR035791|interpro:IPR043136|mint:P14373|reactome:R-HSA-3232142|reactome:R-HSA-9635465|reactome:R-HSA-8948751|ensembl:ENSG00000204713(gene)|ensembl:ENSG00000215641(gene)|ensembl:ENSG00000229006(gene)|ensembl:ENSG00000234495(gene)|ensembl:ENSG00000237071(gene)|ensembl:ENST00000377199(transcript)|ensembl:ENST00000400720(transcript)|ensembl:ENST00000431123(transcript)|ensembl:ENST00000435528(transcript)|ensembl:ENST00000437160(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001650"(fibrillar center)|go:"GO:0002820"(negative regulation of adaptive immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)	rcsb pdb:4Y8T|rcsb pdb:4Y8U|rcsb pdb:4Y9Y|rcsb pdb:4Y9Z|rcsb pdb:4YA0|rcsb pdb:4YA1|rcsb pdb:4YA2|rcsb pdb:4YA3|rcsb pdb:4YA4|rcsb pdb:4YA5|rcsb pdb:4Y7X|rcsb pdb:4Y7Y|rcsb pdb:4Y80|rcsb pdb:4Y81|rcsb pdb:4Y82|rcsb pdb:4Y84|rcsb pdb:4Y8G|rcsb pdb:4Y8H|rcsb pdb:4Y8I|rcsb pdb:4Y8J|rcsb pdb:4Y8K|rcsb pdb:4Y8L|rcsb pdb:4Y8M|rcsb pdb:4Y8N|rcsb pdb:4Y8O|rcsb pdb:4Y8P|rcsb pdb:4Y8Q|rcsb pdb:4Y8R|rcsb pdb:4Y8S|rcsb pdb:5FG7|rcsb pdb:5FG9|rcsb pdb:5FGA|rcsb pdb:4YA7|rcsb pdb:4YA9|rcsb pdb:4Z1L|rcsb pdb:5A5B|rcsb pdb:5AHJ|rcsb pdb:5BOU|rcsb pdb:5BXL|rcsb pdb:5BXN|rcsb pdb:5CGF|rcsb pdb:5CGG|rcsb pdb:5CGH|rcsb pdb:5CGI|rcsb pdb:5CZ4|rcsb pdb:5CZ5|rcsb pdb:5CZ6|rcsb pdb:5CZ7|rcsb pdb:5CZ8|rcsb pdb:5CZ9|rcsb pdb:5CZA|rcsb pdb:5D0S|rcsb pdb:5D0T|rcsb pdb:5D0V|rcsb pdb:5D0W|rcsb pdb:5D0X|rcsb pdb:5D0Z|rcsb pdb:5DKI|rcsb pdb:5DKJ|rcsb pdb:5FGD|rcsb pdb:3HYE|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:3MG0|rcsb pdb:3MG4|rcsb pdb:3MG6|rcsb pdb:3MG7|rcsb pdb:3MG8|rcsb pdb:3NZJ|rcsb pdb:3NZW|rcsb pdb:3NZX|rcsb pdb:3OEU|rcsb pdb:3OEV|rcsb pdb:3OKJ|rcsb pdb:3SDI|rcsb pdb:3SDK|rcsb pdb:3SHJ|rcsb pdb:3TDD|rcsb pdb:3UN4|rcsb pdb:3UN8|rcsb pdb:3WXR|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:4EU2|rcsb pdb:4FZC|rcsb pdb:4FZG|rcsb pdb:4G4S|rcsb pdb:4GK7|rcsb pdb:4HNP|rcsb pdb:4HRC|rcsb pdb:4HRD|rcsb pdb:4INR|rcsb pdb:4INT|rcsb pdb:4INU|rcsb pdb:4J70|rcsb pdb:4JSQ|rcsb pdb:4JSU|rcsb pdb:4JT0|rcsb pdb:4LQI|rcsb pdb:4LTC|rcsb pdb:4NNN|rcsb pdb:4NNW|rcsb pdb:4NO1|rcsb pdb:4NO6|rcsb pdb:4NO8|rcsb pdb:4NO9|rcsb pdb:5FGE|rcsb pdb:5FGF|rcsb pdb:5FGG|rcsb pdb:5FGH|rcsb pdb:5FGI|rcsb pdb:5FHS|rcsb pdb:5JHR|rcsb pdb:5JHS|rcsb pdb:5L52|rcsb pdb:5L54|rcsb pdb:5L55|rcsb pdb:5L5A|rcsb pdb:5L5B|rcsb pdb:5L5D|rcsb pdb:5L5E|rcsb pdb:5L5F|rcsb pdb:5L5H|rcsb pdb:5L5I|rcsb pdb:5L5J|rcsb pdb:5L5O|rcsb pdb:5L5P|rcsb pdb:5L5Q|rcsb pdb:5L5R|rcsb pdb:4Q1S|rcsb pdb:4QBY|rcsb pdb:4QLQ|rcsb pdb:4QLS|rcsb pdb:4QLT|rcsb pdb:4QLU|rcsb pdb:4QLV|rcsb pdb:4QUX|rcsb pdb:4QUY|rcsb pdb:4QV0|rcsb pdb:4QV1|rcsb pdb:4QV3|rcsb pdb:4QV4|rcsb pdb:4QV5|rcsb pdb:4QV6|rcsb pdb:4QV7|rcsb pdb:4QV8|rcsb pdb:4QV9|rcsb pdb:4QVL|ensemblfungi:YMR314W(gene)|ensemblfungi:YMR314W_mRNA(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0042175"(nuclear outer membrane-endoplasmic reticulum membrane network)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR035144|rcsb pdb:1FNT|rcsb pdb:1G0U|rcsb pdb:1G65|rcsb pdb:1JD2|rcsb pdb:1RYP|rcsb pdb:1Z7Q|rcsb pdb:2F16|rcsb pdb:2FAK|rcsb pdb:2GPL|rcsb pdb:2ZCY|rcsb pdb:3BDM|rcsb pdb:3D29|rcsb pdb:3DY3|rcsb pdb:3DY4|rcsb pdb:3E47|rcsb pdb:3GPJ|rcsb pdb:3GPT|rcsb pdb:3GPW|rcsb pdb:4QVM|rcsb pdb:4QVN|rcsb pdb:4QVP|rcsb pdb:4QVQ|rcsb pdb:4QVV|rcsb pdb:4QVW|rcsb pdb:4QVY|rcsb pdb:4QW0|rcsb pdb:4QW1|rcsb pdb:4QW3|rcsb pdb:4QW4|rcsb pdb:4QW5|rcsb pdb:4QW6|rcsb pdb:4QW7|rcsb pdb:4QWF|rcsb pdb:4QWG|rcsb pdb:4QWI|rcsb pdb:4QWJ|rcsb pdb:4QWK|rcsb pdb:4QWL|rcsb pdb:4QWR|rcsb pdb:4QWS|rcsb pdb:4QWU|rcsb pdb:4QWX|rcsb pdb:4QXJ|rcsb pdb:4QZ0|rcsb pdb:4QZ1|rcsb pdb:4QZ2|rcsb pdb:4QZ3|rcsb pdb:4QZ4|rcsb pdb:4QZ5|rcsb pdb:4QZ6|rcsb pdb:4QZ7|rcsb pdb:4QZW|rcsb pdb:4QZX|rcsb pdb:4QZZ|rcsb pdb:4R00|rcsb pdb:4R02|rcsb pdb:4R17|rcsb pdb:4R18|rcsb pdb:4RUR|rcsb pdb:4V7O|rcsb pdb:4X6Z|rcsb pdb:4Y69|rcsb pdb:4Y6A|rcsb pdb:4Y6V|rcsb pdb:4Y6Z|rcsb pdb:4Y70|rcsb pdb:4Y74|rcsb pdb:4Y75|rcsb pdb:4Y77|rcsb pdb:4Y78|rcsb pdb:4Y7W|rcsb pdb:5LTT|rcsb pdb:5M2B|rcsb pdb:5MP9|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5NIF|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6G7F|rcsb pdb:6G8M|rcsb pdb:6G8N|rcsb pdb:6GOP|rcsb pdb:6H39|rcsb pdb:6HTB|rcsb pdb:6HTC|rcsb pdb:6HTD|rcsb pdb:6HTP|rcsb pdb:6HTR|rcsb pdb:6HUB|rcsb pdb:6HUC|rcsb pdb:6HUQ|rcsb pdb:6HUU|rcsb pdb:6HUV|rcsb pdb:6HV3|rcsb pdb:6HV4|rcsb pdb:6HV5|rcsb pdb:6HV7|rcsb pdb:6HVA|rcsb pdb:6HVR|rcsb pdb:6HVS|rcsb pdb:6HVT|rcsb pdb:6HVU|rcsb pdb:6HVV|rcsb pdb:5L5S|rcsb pdb:5L5T|rcsb pdb:5L5U|rcsb pdb:5L5V|rcsb pdb:5L5W|rcsb pdb:5L5X|rcsb pdb:5L5Y|rcsb pdb:5L5Z|rcsb pdb:5L60|rcsb pdb:5L61|rcsb pdb:5L62|rcsb pdb:5L63|rcsb pdb:5L64|rcsb pdb:5L65|rcsb pdb:5L66|rcsb pdb:5L67|rcsb pdb:5L68|rcsb pdb:5L69|rcsb pdb:5L6A|rcsb pdb:5L6B|rcsb pdb:5L6C|rcsb pdb:5LAI|rcsb pdb:5LAJ|rcsb pdb:6HVW|rcsb pdb:6HVX|rcsb pdb:6HVY|rcsb pdb:6HW0|rcsb pdb:6HW3|rcsb pdb:6HW4|rcsb pdb:6HW5|rcsb pdb:6HW6|rcsb pdb:6HW7|rcsb pdb:6HW8|rcsb pdb:6HW9|rcsb pdb:6HWA|rcsb pdb:6HWB|rcsb pdb:6HWC|rcsb pdb:6HWD|rcsb pdb:6HWE|rcsb pdb:6HWF|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2X|rcsb pdb:6J30|rcsb pdb:6ZOU|rcsb pdb:6ZP6|rcsb pdb:6ZP8|rcsb pdb:7LS5|rcsb pdb:7LS6|rcsb pdb:7LSX|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|rcsb pdb:6J2Q|refseq:NP_014045.1|sgd:S000004931|mint:P40302|dip:DIP-1528N	-	-	crc64:C43CBCC1C6B9E39E	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:dsfH5OUghD8KSaTz1SFw9OYVTK49606	rogid:C9GPb0JAklkBz0t/YYqRMNEiQss559292	intact-crc:C75153EF27BCC9E0|rigid:NWGPMzOW08lVjEjcmDD50hI80bY	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q7Z6G3-2	uniprotkb:P40302	intact:EBI-10172876|ensembl:ENSP00000457354|intact:EBI-14062040	intact:EBI-13955|ensemblfungi:YMR314W|uniprotkb:D6W0E1	psi-mi:q7z6g3-2(display_long)|uniprotkb:EFCBP2(gene name synonym)|uniprotkb:Neuronal calcium-binding protein 2(gene name synonym)|uniprotkb:Synaptotagmin-interacting protein 2(gene name synonym)|uniprotkb:NECAB2(gene name)|psi-mi:NECAB2(display_short)	psi-mi:psa6_yeast(display_long)|uniprotkb:PRE5(gene name)|psi-mi:PRE5(display_short)|uniprotkb:YMR314W(locus name)|uniprotkb:YM9924.06(orf name)|uniprotkb:Proteasome component PRE5(gene name synonym)|uniprotkb:Macropain subunit PRE5(gene name synonym)|uniprotkb:Proteinase YSCE subunit PRE5(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit PRE5(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549820|imex:IM-24995-3026	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000103154(gene)|ensembl:ENST00000565691(transcript)|uniprotkb:Q7Z6G3-2(isoform-parent)|intact:EBI-950070(isoform-parent)	rcsb pdb:4Y8T|rcsb pdb:4Y8U|rcsb pdb:4Y9Y|rcsb pdb:4Y9Z|rcsb pdb:4YA0|rcsb pdb:4YA1|rcsb pdb:4YA2|rcsb pdb:4YA3|rcsb pdb:4YA4|rcsb pdb:4YA5|rcsb pdb:4Y7X|rcsb pdb:4Y7Y|rcsb pdb:4Y80|rcsb pdb:4Y81|rcsb pdb:4Y82|rcsb pdb:4Y84|rcsb pdb:4Y8G|rcsb pdb:4Y8H|rcsb pdb:4Y8I|rcsb pdb:4Y8J|rcsb pdb:4Y8K|rcsb pdb:4Y8L|rcsb pdb:4Y8M|rcsb pdb:4Y8N|rcsb pdb:4Y8O|rcsb pdb:4Y8P|rcsb pdb:4Y8Q|rcsb pdb:4Y8R|rcsb pdb:4Y8S|rcsb pdb:5FG7|rcsb pdb:5FG9|rcsb pdb:5FGA|rcsb pdb:4YA7|rcsb pdb:4YA9|rcsb pdb:4Z1L|rcsb pdb:5A5B|rcsb pdb:5AHJ|rcsb pdb:5BOU|rcsb pdb:5BXL|rcsb pdb:5BXN|rcsb pdb:5CGF|rcsb pdb:5CGG|rcsb pdb:5CGH|rcsb pdb:5CGI|rcsb pdb:5CZ4|rcsb pdb:5CZ5|rcsb pdb:5CZ6|rcsb pdb:5CZ7|rcsb pdb:5CZ8|rcsb pdb:5CZ9|rcsb pdb:5CZA|rcsb pdb:5D0S|rcsb pdb:5D0T|rcsb pdb:5D0V|rcsb pdb:5D0W|rcsb pdb:5D0X|rcsb pdb:5D0Z|rcsb pdb:5DKI|rcsb pdb:5DKJ|rcsb pdb:5FGD|rcsb pdb:3HYE|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:3MG0|rcsb pdb:3MG4|rcsb pdb:3MG6|rcsb pdb:3MG7|rcsb pdb:3MG8|rcsb pdb:3NZJ|rcsb pdb:3NZW|rcsb pdb:3NZX|rcsb pdb:3OEU|rcsb pdb:3OEV|rcsb pdb:3OKJ|rcsb pdb:3SDI|rcsb pdb:3SDK|rcsb pdb:3SHJ|rcsb pdb:3TDD|rcsb pdb:3UN4|rcsb pdb:3UN8|rcsb pdb:3WXR|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:4EU2|rcsb pdb:4FZC|rcsb pdb:4FZG|rcsb pdb:4G4S|rcsb pdb:4GK7|rcsb pdb:4HNP|rcsb pdb:4HRC|rcsb pdb:4HRD|rcsb pdb:4INR|rcsb pdb:4INT|rcsb pdb:4INU|rcsb pdb:4J70|rcsb pdb:4JSQ|rcsb pdb:4JSU|rcsb pdb:4JT0|rcsb pdb:4LQI|rcsb pdb:4LTC|rcsb pdb:4NNN|rcsb pdb:4NNW|rcsb pdb:4NO1|rcsb pdb:4NO6|rcsb pdb:4NO8|rcsb pdb:4NO9|rcsb pdb:5FGE|rcsb pdb:5FGF|rcsb pdb:5FGG|rcsb pdb:5FGH|rcsb pdb:5FGI|rcsb pdb:5FHS|rcsb pdb:5JHR|rcsb pdb:5JHS|rcsb pdb:5L52|rcsb pdb:5L54|rcsb pdb:5L55|rcsb pdb:5L5A|rcsb pdb:5L5B|rcsb pdb:5L5D|rcsb pdb:5L5E|rcsb pdb:5L5F|rcsb pdb:5L5H|rcsb pdb:5L5I|rcsb pdb:5L5J|rcsb pdb:5L5O|rcsb pdb:5L5P|rcsb pdb:5L5Q|rcsb pdb:5L5R|rcsb pdb:4Q1S|rcsb pdb:4QBY|rcsb pdb:4QLQ|rcsb pdb:4QLS|rcsb pdb:4QLT|rcsb pdb:4QLU|rcsb pdb:4QLV|rcsb pdb:4QUX|rcsb pdb:4QUY|rcsb pdb:4QV0|rcsb pdb:4QV1|rcsb pdb:4QV3|rcsb pdb:4QV4|rcsb pdb:4QV5|rcsb pdb:4QV6|rcsb pdb:4QV7|rcsb pdb:4QV8|rcsb pdb:4QV9|rcsb pdb:4QVL|ensemblfungi:YMR314W(gene)|ensemblfungi:YMR314W_mRNA(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0042175"(nuclear outer membrane-endoplasmic reticulum membrane network)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR035144|rcsb pdb:1FNT|rcsb pdb:1G0U|rcsb pdb:1G65|rcsb pdb:1JD2|rcsb pdb:1RYP|rcsb pdb:1Z7Q|rcsb pdb:2F16|rcsb pdb:2FAK|rcsb pdb:2GPL|rcsb pdb:2ZCY|rcsb pdb:3BDM|rcsb pdb:3D29|rcsb pdb:3DY3|rcsb pdb:3DY4|rcsb pdb:3E47|rcsb pdb:3GPJ|rcsb pdb:3GPT|rcsb pdb:3GPW|rcsb pdb:4QVM|rcsb pdb:4QVN|rcsb pdb:4QVP|rcsb pdb:4QVQ|rcsb pdb:4QVV|rcsb pdb:4QVW|rcsb pdb:4QVY|rcsb pdb:4QW0|rcsb pdb:4QW1|rcsb pdb:4QW3|rcsb pdb:4QW4|rcsb pdb:4QW5|rcsb pdb:4QW6|rcsb pdb:4QW7|rcsb pdb:4QWF|rcsb pdb:4QWG|rcsb pdb:4QWI|rcsb pdb:4QWJ|rcsb pdb:4QWK|rcsb pdb:4QWL|rcsb pdb:4QWR|rcsb pdb:4QWS|rcsb pdb:4QWU|rcsb pdb:4QWX|rcsb pdb:4QXJ|rcsb pdb:4QZ0|rcsb pdb:4QZ1|rcsb pdb:4QZ2|rcsb pdb:4QZ3|rcsb pdb:4QZ4|rcsb pdb:4QZ5|rcsb pdb:4QZ6|rcsb pdb:4QZ7|rcsb pdb:4QZW|rcsb pdb:4QZX|rcsb pdb:4QZZ|rcsb pdb:4R00|rcsb pdb:4R02|rcsb pdb:4R17|rcsb pdb:4R18|rcsb pdb:4RUR|rcsb pdb:4V7O|rcsb pdb:4X6Z|rcsb pdb:4Y69|rcsb pdb:4Y6A|rcsb pdb:4Y6V|rcsb pdb:4Y6Z|rcsb pdb:4Y70|rcsb pdb:4Y74|rcsb pdb:4Y75|rcsb pdb:4Y77|rcsb pdb:4Y78|rcsb pdb:4Y7W|rcsb pdb:5LTT|rcsb pdb:5M2B|rcsb pdb:5MP9|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5NIF|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6G7F|rcsb pdb:6G8M|rcsb pdb:6G8N|rcsb pdb:6GOP|rcsb pdb:6H39|rcsb pdb:6HTB|rcsb pdb:6HTC|rcsb pdb:6HTD|rcsb pdb:6HTP|rcsb pdb:6HTR|rcsb pdb:6HUB|rcsb pdb:6HUC|rcsb pdb:6HUQ|rcsb pdb:6HUU|rcsb pdb:6HUV|rcsb pdb:6HV3|rcsb pdb:6HV4|rcsb pdb:6HV5|rcsb pdb:6HV7|rcsb pdb:6HVA|rcsb pdb:6HVR|rcsb pdb:6HVS|rcsb pdb:6HVT|rcsb pdb:6HVU|rcsb pdb:6HVV|rcsb pdb:5L5S|rcsb pdb:5L5T|rcsb pdb:5L5U|rcsb pdb:5L5V|rcsb pdb:5L5W|rcsb pdb:5L5X|rcsb pdb:5L5Y|rcsb pdb:5L5Z|rcsb pdb:5L60|rcsb pdb:5L61|rcsb pdb:5L62|rcsb pdb:5L63|rcsb pdb:5L64|rcsb pdb:5L65|rcsb pdb:5L66|rcsb pdb:5L67|rcsb pdb:5L68|rcsb pdb:5L69|rcsb pdb:5L6A|rcsb pdb:5L6B|rcsb pdb:5L6C|rcsb pdb:5LAI|rcsb pdb:5LAJ|rcsb pdb:6HVW|rcsb pdb:6HVX|rcsb pdb:6HVY|rcsb pdb:6HW0|rcsb pdb:6HW3|rcsb pdb:6HW4|rcsb pdb:6HW5|rcsb pdb:6HW6|rcsb pdb:6HW7|rcsb pdb:6HW8|rcsb pdb:6HW9|rcsb pdb:6HWA|rcsb pdb:6HWB|rcsb pdb:6HWC|rcsb pdb:6HWD|rcsb pdb:6HWE|rcsb pdb:6HWF|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2X|rcsb pdb:6J30|rcsb pdb:6ZOU|rcsb pdb:6ZP6|rcsb pdb:6ZP8|rcsb pdb:7LS5|rcsb pdb:7LS6|rcsb pdb:7LSX|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|rcsb pdb:6J2Q|refseq:NP_014045.1|sgd:S000004931|mint:P40302|dip:DIP-1528N	-	-	crc64:C43CBCC1C6B9E39E	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:4S7oIx6h+mKzV3EPxqcfMNqaNko9606	rogid:C9GPb0JAklkBz0t/YYqRMNEiQss559292	intact-crc:9D5C505AEAC8B95A|rigid:S01jGR6LjAADiaZ9tYOiC9wrNaM	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:A9UHW6-2	uniprotkb:P40302	intact:EBI-9118295|ensembl:ENSP00000245551	intact:EBI-13955|ensemblfungi:YMR314W|uniprotkb:D6W0E1	psi-mi:a9uhw6-2(display_long)|uniprotkb:MIF4GD(gene name)|psi-mi:MIF4GD(display_short)|uniprotkb:SLIP1(gene name synonym)|uniprotkb:SLBP-interacting protein 1(gene name synonym)	psi-mi:psa6_yeast(display_long)|uniprotkb:PRE5(gene name)|psi-mi:PRE5(display_short)|uniprotkb:YMR314W(locus name)|uniprotkb:YM9924.06(orf name)|uniprotkb:Proteasome component PRE5(gene name synonym)|uniprotkb:Macropain subunit PRE5(gene name synonym)|uniprotkb:Proteinase YSCE subunit PRE5(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit PRE5(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549816|imex:IM-24995-3025	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-373498(isoform-parent)|ensembl:ENSG00000125457(gene)|ensembl:ENST00000245551(transcript)|uniprotkb:A9UHW6-2(isoform-parent)	rcsb pdb:4Y8T|rcsb pdb:4Y8U|rcsb pdb:4Y9Y|rcsb pdb:4Y9Z|rcsb pdb:4YA0|rcsb pdb:4YA1|rcsb pdb:4YA2|rcsb pdb:4YA3|rcsb pdb:4YA4|rcsb pdb:4YA5|rcsb pdb:4Y7X|rcsb pdb:4Y7Y|rcsb pdb:4Y80|rcsb pdb:4Y81|rcsb pdb:4Y82|rcsb pdb:4Y84|rcsb pdb:4Y8G|rcsb pdb:4Y8H|rcsb pdb:4Y8I|rcsb pdb:4Y8J|rcsb pdb:4Y8K|rcsb pdb:4Y8L|rcsb pdb:4Y8M|rcsb pdb:4Y8N|rcsb pdb:4Y8O|rcsb pdb:4Y8P|rcsb pdb:4Y8Q|rcsb pdb:4Y8R|rcsb pdb:4Y8S|rcsb pdb:5FG7|rcsb pdb:5FG9|rcsb pdb:5FGA|rcsb pdb:4YA7|rcsb pdb:4YA9|rcsb pdb:4Z1L|rcsb pdb:5A5B|rcsb pdb:5AHJ|rcsb pdb:5BOU|rcsb pdb:5BXL|rcsb pdb:5BXN|rcsb pdb:5CGF|rcsb pdb:5CGG|rcsb pdb:5CGH|rcsb pdb:5CGI|rcsb pdb:5CZ4|rcsb pdb:5CZ5|rcsb pdb:5CZ6|rcsb pdb:5CZ7|rcsb pdb:5CZ8|rcsb pdb:5CZ9|rcsb pdb:5CZA|rcsb pdb:5D0S|rcsb pdb:5D0T|rcsb pdb:5D0V|rcsb pdb:5D0W|rcsb pdb:5D0X|rcsb pdb:5D0Z|rcsb pdb:5DKI|rcsb pdb:5DKJ|rcsb pdb:5FGD|rcsb pdb:3HYE|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:3MG0|rcsb pdb:3MG4|rcsb pdb:3MG6|rcsb pdb:3MG7|rcsb pdb:3MG8|rcsb pdb:3NZJ|rcsb pdb:3NZW|rcsb pdb:3NZX|rcsb pdb:3OEU|rcsb pdb:3OEV|rcsb pdb:3OKJ|rcsb pdb:3SDI|rcsb pdb:3SDK|rcsb pdb:3SHJ|rcsb pdb:3TDD|rcsb pdb:3UN4|rcsb pdb:3UN8|rcsb pdb:3WXR|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:4EU2|rcsb pdb:4FZC|rcsb pdb:4FZG|rcsb pdb:4G4S|rcsb pdb:4GK7|rcsb pdb:4HNP|rcsb pdb:4HRC|rcsb pdb:4HRD|rcsb pdb:4INR|rcsb pdb:4INT|rcsb pdb:4INU|rcsb pdb:4J70|rcsb pdb:4JSQ|rcsb pdb:4JSU|rcsb pdb:4JT0|rcsb pdb:4LQI|rcsb pdb:4LTC|rcsb pdb:4NNN|rcsb pdb:4NNW|rcsb pdb:4NO1|rcsb pdb:4NO6|rcsb pdb:4NO8|rcsb pdb:4NO9|rcsb pdb:5FGE|rcsb pdb:5FGF|rcsb pdb:5FGG|rcsb pdb:5FGH|rcsb pdb:5FGI|rcsb pdb:5FHS|rcsb pdb:5JHR|rcsb pdb:5JHS|rcsb pdb:5L52|rcsb pdb:5L54|rcsb pdb:5L55|rcsb pdb:5L5A|rcsb pdb:5L5B|rcsb pdb:5L5D|rcsb pdb:5L5E|rcsb pdb:5L5F|rcsb pdb:5L5H|rcsb pdb:5L5I|rcsb pdb:5L5J|rcsb pdb:5L5O|rcsb pdb:5L5P|rcsb pdb:5L5Q|rcsb pdb:5L5R|rcsb pdb:4Q1S|rcsb pdb:4QBY|rcsb pdb:4QLQ|rcsb pdb:4QLS|rcsb pdb:4QLT|rcsb pdb:4QLU|rcsb pdb:4QLV|rcsb pdb:4QUX|rcsb pdb:4QUY|rcsb pdb:4QV0|rcsb pdb:4QV1|rcsb pdb:4QV3|rcsb pdb:4QV4|rcsb pdb:4QV5|rcsb pdb:4QV6|rcsb pdb:4QV7|rcsb pdb:4QV8|rcsb pdb:4QV9|rcsb pdb:4QVL|ensemblfungi:YMR314W(gene)|ensemblfungi:YMR314W_mRNA(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0042175"(nuclear outer membrane-endoplasmic reticulum membrane network)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR035144|rcsb pdb:1FNT|rcsb pdb:1G0U|rcsb pdb:1G65|rcsb pdb:1JD2|rcsb pdb:1RYP|rcsb pdb:1Z7Q|rcsb pdb:2F16|rcsb pdb:2FAK|rcsb pdb:2GPL|rcsb pdb:2ZCY|rcsb pdb:3BDM|rcsb pdb:3D29|rcsb pdb:3DY3|rcsb pdb:3DY4|rcsb pdb:3E47|rcsb pdb:3GPJ|rcsb pdb:3GPT|rcsb pdb:3GPW|rcsb pdb:4QVM|rcsb pdb:4QVN|rcsb pdb:4QVP|rcsb pdb:4QVQ|rcsb pdb:4QVV|rcsb pdb:4QVW|rcsb pdb:4QVY|rcsb pdb:4QW0|rcsb pdb:4QW1|rcsb pdb:4QW3|rcsb pdb:4QW4|rcsb pdb:4QW5|rcsb pdb:4QW6|rcsb pdb:4QW7|rcsb pdb:4QWF|rcsb pdb:4QWG|rcsb pdb:4QWI|rcsb pdb:4QWJ|rcsb pdb:4QWK|rcsb pdb:4QWL|rcsb pdb:4QWR|rcsb pdb:4QWS|rcsb pdb:4QWU|rcsb pdb:4QWX|rcsb pdb:4QXJ|rcsb pdb:4QZ0|rcsb pdb:4QZ1|rcsb pdb:4QZ2|rcsb pdb:4QZ3|rcsb pdb:4QZ4|rcsb pdb:4QZ5|rcsb pdb:4QZ6|rcsb pdb:4QZ7|rcsb pdb:4QZW|rcsb pdb:4QZX|rcsb pdb:4QZZ|rcsb pdb:4R00|rcsb pdb:4R02|rcsb pdb:4R17|rcsb pdb:4R18|rcsb pdb:4RUR|rcsb pdb:4V7O|rcsb pdb:4X6Z|rcsb pdb:4Y69|rcsb pdb:4Y6A|rcsb pdb:4Y6V|rcsb pdb:4Y6Z|rcsb pdb:4Y70|rcsb pdb:4Y74|rcsb pdb:4Y75|rcsb pdb:4Y77|rcsb pdb:4Y78|rcsb pdb:4Y7W|rcsb pdb:5LTT|rcsb pdb:5M2B|rcsb pdb:5MP9|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5NIF|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6G7F|rcsb pdb:6G8M|rcsb pdb:6G8N|rcsb pdb:6GOP|rcsb pdb:6H39|rcsb pdb:6HTB|rcsb pdb:6HTC|rcsb pdb:6HTD|rcsb pdb:6HTP|rcsb pdb:6HTR|rcsb pdb:6HUB|rcsb pdb:6HUC|rcsb pdb:6HUQ|rcsb pdb:6HUU|rcsb pdb:6HUV|rcsb pdb:6HV3|rcsb pdb:6HV4|rcsb pdb:6HV5|rcsb pdb:6HV7|rcsb pdb:6HVA|rcsb pdb:6HVR|rcsb pdb:6HVS|rcsb pdb:6HVT|rcsb pdb:6HVU|rcsb pdb:6HVV|rcsb pdb:5L5S|rcsb pdb:5L5T|rcsb pdb:5L5U|rcsb pdb:5L5V|rcsb pdb:5L5W|rcsb pdb:5L5X|rcsb pdb:5L5Y|rcsb pdb:5L5Z|rcsb pdb:5L60|rcsb pdb:5L61|rcsb pdb:5L62|rcsb pdb:5L63|rcsb pdb:5L64|rcsb pdb:5L65|rcsb pdb:5L66|rcsb pdb:5L67|rcsb pdb:5L68|rcsb pdb:5L69|rcsb pdb:5L6A|rcsb pdb:5L6B|rcsb pdb:5L6C|rcsb pdb:5LAI|rcsb pdb:5LAJ|rcsb pdb:6HVW|rcsb pdb:6HVX|rcsb pdb:6HVY|rcsb pdb:6HW0|rcsb pdb:6HW3|rcsb pdb:6HW4|rcsb pdb:6HW5|rcsb pdb:6HW6|rcsb pdb:6HW7|rcsb pdb:6HW8|rcsb pdb:6HW9|rcsb pdb:6HWA|rcsb pdb:6HWB|rcsb pdb:6HWC|rcsb pdb:6HWD|rcsb pdb:6HWE|rcsb pdb:6HWF|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2X|rcsb pdb:6J30|rcsb pdb:6ZOU|rcsb pdb:6ZP6|rcsb pdb:6ZP8|rcsb pdb:7LS5|rcsb pdb:7LS6|rcsb pdb:7LSX|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|rcsb pdb:6J2Q|refseq:NP_014045.1|sgd:S000004931|mint:P40302|dip:DIP-1528N	-	-	crc64:C43CBCC1C6B9E39E	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:XBdXA9tE5Tk5Pn7mO+RIKrlqhEM9606	rogid:C9GPb0JAklkBz0t/YYqRMNEiQss559292	intact-crc:9AF729C80A636916|rigid:7wBQ45RgYl7SXSUSonM+ak+4HdU	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P40087	uniprotkb:O14641	intact:EBI-5717|uniprotkb:D3DM50|ensemblfungi:YER143W	intact:EBI-740850|ensembl:ENSP00000005340|uniprotkb:Q53XM0|uniprotkb:D3DTN3	psi-mi:ddi1_yeast(display_long)|uniprotkb:DDI1(gene name)|psi-mi:DDI1(display_short)|uniprotkb:v-SNARE-master 1(gene name synonym)|uniprotkb:VSM1(gene name synonym)|uniprotkb:YER143W(locus name)	psi-mi:dvl2_human(display_long)|uniprotkb:DSH homolog 2(gene name synonym)|uniprotkb:DVL2(gene name)|psi-mi:DVL2(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549792|imex:IM-24995-3019	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000000945|refseq:NP_011070.3|dip:DIP-1216N|mint:P40087|rcsb pdb:2MRP|rcsb pdb:2MWS|rcsb pdb:2N7E|rcsb pdb:4Z2Z|rcsb pdb:5KES|ensemblfungi:YER143W(gene)|ensemblfungi:YER143W_mRNA(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0004190"(aspartic-type endopeptidase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0009306"(protein secretion)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043328"(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0072710"(response to hydroxyurea)|go:"GO:1904855"(proteasome regulatory particle binding)|interpro:IPR001995(Peptidase A2A, retrovirus, catalytic)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR019103|interpro:IPR021109|interpro:IPR033882|rcsb pdb:2I1A|rcsb pdb:2MR9|rcsb pdb:2MRO	refseq:NP_004413.1|ensembl:ENSG00000004975(gene)|ensembl:ENST00000005340(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005109"(frizzled binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0007507"(heart development)|go:"GO:0016235"(aggresome)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044340"(canonical Wnt signaling pathway involved in regulation of cell proliferation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0150012"(positive regulation of neuron projection arborization)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008341(Dishevelled-2 region)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:O14641|rcsb pdb:2REY|rcsb pdb:3CBX|rcsb pdb:3CBY|rcsb pdb:3CBZ|rcsb pdb:3CC0|rcsb pdb:4WIP|rcsb pdb:5LNP|rcsb pdb:5SUY|rcsb pdb:5SUZ|rcsb pdb:6IW3|rcsb pdb:6JCK|reactome:R-HSA-201681|reactome:R-HSA-201688|reactome:R-HSA-2028269|reactome:R-HSA-4086400|reactome:R-HSA-4608870|reactome:R-HSA-4641258|reactome:R-HSA-4641262|reactome:R-HSA-5099900|reactome:R-HSA-5368598|reactome:R-HSA-5663220|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9673324|ensembl:ENSP00000005340|dip:DIP-34433N	-	crc64:B43425B029B7658B	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:DHcLrKv/gQNKEXCievX6k6ikKL0559292	rogid:2Vdc8oRnT4Mz/j+EXQXrL3AszOc9606	intact-crc:F746F888863BA2B8|rigid:GeUpq3+MJUcBavhPhRoJUMMCLdE	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O75821	uniprotkb:P40217	intact:EBI-366632|uniprotkb:O14801|uniprotkb:Q969U5|intact:EBI-28974438|ensembl:ENSP00000253108	intact:EBI-8951|ensemblfungi:YMR146C|uniprotkb:D6VZW8	psi-mi:eif3g_human(display_long)|uniprotkb:EIF3G(gene name)|psi-mi:EIF3G(display_short)|uniprotkb:EIF3S4(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 4(gene name synonym)|uniprotkb:eIF-3-delta(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 RNA-binding subunit(gene name synonym)|uniprotkb:eIF3 p44(gene name synonym)|uniprotkb:eIF3 p42(gene name synonym)	psi-mi:eif3i_yeast(display_long)|uniprotkb:TIF34(gene name)|psi-mi:TIF34(display_short)|uniprotkb:YMR146C(locus name)|uniprotkb:YM9375.16C(orf name)|uniprotkb:Eukaryotic translation initiation factor 3 39 kDa subunit(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549808|imex:IM-24995-3023	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000253108|refseq:NP_003746.2|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0075525"(viral translational termination-reinitiation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR017334(Translation initiation factor 3, RNA-binding subunit)|interpro:IPR024675|interpro:IPR034240|interpro:IPR035979|mint:O75821|rcsb pdb:2CQ0|rcsb pdb:2MJC|rcsb pdb:5K0Y|rcsb pdb:6YBS|rcsb pdb:6ZMW|reactome:R-HSA-156827|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|ensembl:ENSG00000130811(gene)|ensembl:ENST00000253108(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|dip:DIP-31115N	ensemblfungi:YMR146C(gene)|ensemblfungi:YMR146C_mRNA(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0002183"(cytoplasmic translational initiation)|go:"GO:0002188"(translation reinitiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0043614"(multi-eIF complex)|go:"GO:0071541"(eukaryotic translation initiation factor 3 complex, eIF3m)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR027525|interpro:IPR036322|rcsb pdb:3JAP|rcsb pdb:3JAQ|rcsb pdb:3ZWL|rcsb pdb:5A5U|rcsb pdb:6FYX|rcsb pdb:6FYY|rcsb pdb:6GSM|rcsb pdb:6GSN|rcsb pdb:6ZCE|rcsb pdb:6ZU9|reactome:R-SCE-156827|reactome:R-SCE-72649|reactome:R-SCE-72695|reactome:R-SCE-72702|refseq:NP_013866.1|sgd:S000004754|mint:P40217|dip:DIP-2520N	-	-	crc64:E6C0D0B275E87622	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:ZHm8Il08Zyb6kFAavZo4tnuUN4g9606	rogid:yiEGZUsT5RdaocsqZq2BUELIsR8559292	intact-crc:50CDF6984663DB4E|rigid:vzNfpj9VStpaFdO/Ylg0KfiZkgA	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O60684	uniprotkb:P40151	intact:EBI-359923|uniprotkb:Q5VVU3|uniprotkb:B2RDC7|ensembl:ENSP00000362728|uniprotkb:D3DPP5	intact:EBI-29152|uniprotkb:D6W0X2|ensemblfungi:YNL218W	psi-mi:ima7_human(display_long)|uniprotkb:KPNA6(gene name)|psi-mi:KPNA6(display_short)|uniprotkb:IPOA7(gene name synonym)|uniprotkb:Karyopherin subunit alpha-6(gene name synonym)	psi-mi:wrip1_yeast(display_long)|uniprotkb:Maintenance of genome stability protein 1(gene name synonym)|uniprotkb:YNL218W(locus name)|uniprotkb:N1302(orf name)|uniprotkb:MGS1(gene name)|psi-mi:MGS1(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549804|imex:IM-24995-3022	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_036448.1|ensembl:ENSG00000025800(gene)|ensembl:ENST00000373625(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0016020"(membrane)|go:"GO:0019079"(viral genome replication)|go:"GO:0030682"(mitigation of host defenses by symbiont)|go:"GO:0043657"(host cell)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060135"(maternal process involved in female pregnancy)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0075506"(entry of viral genome into host nucleus through nuclear pore complex via importin)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:1903902"(positive regulation of viral life cycle)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|mint:O60684|rcsb pdb:4UAD|dip:DIP-27609N	refseq:NP_014181.1|sgd:S000005162|dip:DIP-1638N|ensemblfungi:YNL218W(gene)|ensemblfungi:YNL218W_mRNA(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0017116"(single-stranded DNA helicase activity)|go:"GO:0033567"(DNA replication, Okazaki fragment processing)|go:"GO:0046872"(metal ion binding)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR006642(Zinc finger, Rad18-type putative)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR021886|interpro:IPR027417|interpro:IPR032423	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:3NsSIcE6BHIqYlvfGRolUKD/5uc9606	rogid:p3Wxu3/I3MK3y5fH85a0FFsg2Qo559292	intact-crc:BE9ED500F4A568C0|rigid:V7syCjAy9ACvfvoaFtDSyAjbkwI	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P40099	uniprotkb:P13196	intact:EBI-2059710|uniprotkb:D3DM92|ensemblfungi:YER183C	intact:EBI-3905054|ensembl:ENSP00000309259|ensembl:ENSP00000378416|ensembl:ENSP00000417719|ensembl:ENSP00000418779	psi-mi:fthc_yeast(display_long)|uniprotkb:FAU1(gene name)|psi-mi:FAU1(display_short)|uniprotkb:5,10-methenyl-tetrahydrofolate synthetase(gene name synonym)|uniprotkb:YER183C(locus name)	psi-mi:hem1_human(display_long)|uniprotkb:ALAS1(gene name)|psi-mi:ALAS1(display_short)|uniprotkb:ALAS3(gene name synonym)|uniprotkb:ALASH(gene name synonym)|uniprotkb:5-aminolevulinic acid synthase 1(gene name synonym)|uniprotkb:Delta-ALA synthase 1(gene name synonym)|uniprotkb:Delta-aminolevulinate synthase 1(gene name synonym)|uniprotkb:OK/SW-cl.121(orf name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549800|imex:IM-24995-3021	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	reactome:R-SCE-196757|refseq:NP_011110.1|sgd:S000000985|interpro:IPR002698(5-formyltetrahydrofolate cyclo-ligase)|interpro:IPR024185|interpro:IPR037171|ensemblfungi:YER183C(gene)|ensemblfungi:YER183C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0009396"(folic acid-containing compound biosynthetic process)|go:"GO:0030272"(5-formyltetrahydrofolate cyclo-ligase activity)|go:"GO:0035999"(tetrahydrofolate interconversion)	refseq:NP_001291372.1|refseq:NP_001291373.1|refseq:NP_000679.1|refseq:NP_954635.1|go:"GO:0006783"(heme biosynthetic process)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0042541"(hemoglobin biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0048821"(erythrocyte development)|ensembl:ENSG00000023330(gene)|ensembl:ENST00000310271(transcript)|ensembl:ENST00000394965(transcript)|ensembl:ENST00000469224(transcript)|ensembl:ENST00000484952(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0003870"(5-aminolevulinate synthase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|interpro:IPR001917(Aminotransferase, class-II, pyridoxal-phosphate binding site)|interpro:IPR004839(Aminotransferase, class I and II)|interpro:IPR010961(Tetrapyrrole biosynthesis, 5-aminolevulinic acid synthase)|interpro:IPR015118(5-aminolevulinate synthase presequence)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|mint:P13196|reactome:R-HSA-189451|reactome:R-HSA-1989781|reactome:R-HSA-2151201|go:"GO:0006782"(protoporphyrinogen IX biosynthetic process)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:dS0v0wrvp9isCvc/Sp4d5aiOhnY559292	rogid:HFjJ6zrRF9UYD7LMB6A3CcxcS7c9606	intact-crc:DF2B6AA126DACB25|rigid:ux1CwXxyarshXQ76Iz25Fcf2c8A	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P40099	uniprotkb:A0A0C4DFM5	intact:EBI-2059710|uniprotkb:D3DM92|ensemblfungi:YER183C	intact:EBI-11530418|ensembl:ENSP00000239926	psi-mi:fthc_yeast(display_long)|uniprotkb:FAU1(gene name)|psi-mi:FAU1(display_short)|uniprotkb:5,10-methenyl-tetrahydrofolate synthetase(gene name synonym)|uniprotkb:YER183C(locus name)	psi-mi:a0a0c4dfm5_human(display_long)|uniprotkb:hCG_39937(orf name)|uniprotkb:MYOT(gene name)|psi-mi:MYOT(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549796|imex:IM-24995-3020	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	reactome:R-SCE-196757|refseq:NP_011110.1|sgd:S000000985|interpro:IPR002698(5-formyltetrahydrofolate cyclo-ligase)|interpro:IPR024185|interpro:IPR037171|ensemblfungi:YER183C(gene)|ensemblfungi:YER183C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0009396"(folic acid-containing compound biosynthetic process)|go:"GO:0030272"(5-formyltetrahydrofolate cyclo-ligase activity)|go:"GO:0035999"(tetrahydrofolate interconversion)	refseq:NP_006781.1|ensembl:ENSG00000120729(gene)|ensembl:ENST00000239926(transcript)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:dS0v0wrvp9isCvc/Sp4d5aiOhnY559292	rogid:ggHzlR2dbSQfddxEwJplKIQXGK89606	intact-crc:E624848629AD3BEB|rigid:a7sWIXwPEmsQ7O7UxJl9GvBu72M	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O75936	uniprotkb:P40302	intact:EBI-715662|uniprotkb:Q6IBJ2|ensembl:ENSP00000263182|ensembl:ENSP00000433772|ensembl:ENSP00000434918|ensembl:ENSP00000435781|uniprotkb:B2R8L7|uniprotkb:D3DQZ1	intact:EBI-13955|ensemblfungi:YMR314W|uniprotkb:D6W0E1	psi-mi:bodg_human(display_long)|uniprotkb:Gamma-butyrobetaine,2-oxoglutarate dioxygenase(gene name synonym)|uniprotkb:Gamma-butyrobetaine hydroxylase(gene name synonym)|uniprotkb:BBOX1(gene name)|psi-mi:BBOX1(display_short)|uniprotkb:BBH(gene name synonym)|uniprotkb:BBOX(gene name synonym)	psi-mi:psa6_yeast(display_long)|uniprotkb:PRE5(gene name)|psi-mi:PRE5(display_short)|uniprotkb:YMR314W(locus name)|uniprotkb:YM9924.06(orf name)|uniprotkb:Proteasome component PRE5(gene name synonym)|uniprotkb:Macropain subunit PRE5(gene name synonym)|uniprotkb:Proteinase YSCE subunit PRE5(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit PRE5(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549812|imex:IM-24995-3024	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003977.1|refseq:XP_005253216.1|refseq:XP_005253217.1|refseq:XP_005253218.1|ensembl:ENSG00000129151(gene)|ensembl:ENST00000263182(transcript)|ensembl:ENST00000525090(transcript)|ensembl:ENST00000528583(transcript)|ensembl:ENST00000529202(transcript)|go:"GO:0005506"(iron ion binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008336"(gamma-butyrobetaine dioxygenase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0045329"(carnitine biosynthetic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR003819(Taurine catabolism dioxygenase TauD/TfdA)|interpro:IPR010376(Protein of unknown function DUF971)|interpro:IPR012775(Gamma-butyrobetaine,2-oxoglutarate dioxygenase)|interpro:IPR038492|interpro:IPR042098|mint:O75936|rcsb pdb:3MS5|rcsb pdb:3N6W|rcsb pdb:3O2G|rcsb pdb:4BG1|rcsb pdb:4BGK|rcsb pdb:4BGM|rcsb pdb:4BHF|rcsb pdb:4BHG|rcsb pdb:4BHI|rcsb pdb:4C5W|rcsb pdb:4C8R|rcsb pdb:4CWD|reactome:R-HSA-71262|refseq:XP_011518704.1|refseq:XP_016873892.1	rcsb pdb:4Y8T|rcsb pdb:4Y8U|rcsb pdb:4Y9Y|rcsb pdb:4Y9Z|rcsb pdb:4YA0|rcsb pdb:4YA1|rcsb pdb:4YA2|rcsb pdb:4YA3|rcsb pdb:4YA4|rcsb pdb:4YA5|rcsb pdb:4Y7X|rcsb pdb:4Y7Y|rcsb pdb:4Y80|rcsb pdb:4Y81|rcsb pdb:4Y82|rcsb pdb:4Y84|rcsb pdb:4Y8G|rcsb pdb:4Y8H|rcsb pdb:4Y8I|rcsb pdb:4Y8J|rcsb pdb:4Y8K|rcsb pdb:4Y8L|rcsb pdb:4Y8M|rcsb pdb:4Y8N|rcsb pdb:4Y8O|rcsb pdb:4Y8P|rcsb pdb:4Y8Q|rcsb pdb:4Y8R|rcsb pdb:4Y8S|rcsb pdb:5FG7|rcsb pdb:5FG9|rcsb pdb:5FGA|rcsb pdb:4YA7|rcsb pdb:4YA9|rcsb pdb:4Z1L|rcsb pdb:5A5B|rcsb pdb:5AHJ|rcsb pdb:5BOU|rcsb pdb:5BXL|rcsb pdb:5BXN|rcsb pdb:5CGF|rcsb pdb:5CGG|rcsb pdb:5CGH|rcsb pdb:5CGI|rcsb pdb:5CZ4|rcsb pdb:5CZ5|rcsb pdb:5CZ6|rcsb pdb:5CZ7|rcsb pdb:5CZ8|rcsb pdb:5CZ9|rcsb pdb:5CZA|rcsb pdb:5D0S|rcsb pdb:5D0T|rcsb pdb:5D0V|rcsb pdb:5D0W|rcsb pdb:5D0X|rcsb pdb:5D0Z|rcsb pdb:5DKI|rcsb pdb:5DKJ|rcsb pdb:5FGD|rcsb pdb:3HYE|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:3MG0|rcsb pdb:3MG4|rcsb pdb:3MG6|rcsb pdb:3MG7|rcsb pdb:3MG8|rcsb pdb:3NZJ|rcsb pdb:3NZW|rcsb pdb:3NZX|rcsb pdb:3OEU|rcsb pdb:3OEV|rcsb pdb:3OKJ|rcsb pdb:3SDI|rcsb pdb:3SDK|rcsb pdb:3SHJ|rcsb pdb:3TDD|rcsb pdb:3UN4|rcsb pdb:3UN8|rcsb pdb:3WXR|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:4EU2|rcsb pdb:4FZC|rcsb pdb:4FZG|rcsb pdb:4G4S|rcsb pdb:4GK7|rcsb pdb:4HNP|rcsb pdb:4HRC|rcsb pdb:4HRD|rcsb pdb:4INR|rcsb pdb:4INT|rcsb pdb:4INU|rcsb pdb:4J70|rcsb pdb:4JSQ|rcsb pdb:4JSU|rcsb pdb:4JT0|rcsb pdb:4LQI|rcsb pdb:4LTC|rcsb pdb:4NNN|rcsb pdb:4NNW|rcsb pdb:4NO1|rcsb pdb:4NO6|rcsb pdb:4NO8|rcsb pdb:4NO9|rcsb pdb:5FGE|rcsb pdb:5FGF|rcsb pdb:5FGG|rcsb pdb:5FGH|rcsb pdb:5FGI|rcsb pdb:5FHS|rcsb pdb:5JHR|rcsb pdb:5JHS|rcsb pdb:5L52|rcsb pdb:5L54|rcsb pdb:5L55|rcsb pdb:5L5A|rcsb pdb:5L5B|rcsb pdb:5L5D|rcsb pdb:5L5E|rcsb pdb:5L5F|rcsb pdb:5L5H|rcsb pdb:5L5I|rcsb pdb:5L5J|rcsb pdb:5L5O|rcsb pdb:5L5P|rcsb pdb:5L5Q|rcsb pdb:5L5R|rcsb pdb:4Q1S|rcsb pdb:4QBY|rcsb pdb:4QLQ|rcsb pdb:4QLS|rcsb pdb:4QLT|rcsb pdb:4QLU|rcsb pdb:4QLV|rcsb pdb:4QUX|rcsb pdb:4QUY|rcsb pdb:4QV0|rcsb pdb:4QV1|rcsb pdb:4QV3|rcsb pdb:4QV4|rcsb pdb:4QV5|rcsb pdb:4QV6|rcsb pdb:4QV7|rcsb pdb:4QV8|rcsb pdb:4QV9|rcsb pdb:4QVL|ensemblfungi:YMR314W(gene)|ensemblfungi:YMR314W_mRNA(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0042175"(nuclear outer membrane-endoplasmic reticulum membrane network)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR035144|rcsb pdb:1FNT|rcsb pdb:1G0U|rcsb pdb:1G65|rcsb pdb:1JD2|rcsb pdb:1RYP|rcsb pdb:1Z7Q|rcsb pdb:2F16|rcsb pdb:2FAK|rcsb pdb:2GPL|rcsb pdb:2ZCY|rcsb pdb:3BDM|rcsb pdb:3D29|rcsb pdb:3DY3|rcsb pdb:3DY4|rcsb pdb:3E47|rcsb pdb:3GPJ|rcsb pdb:3GPT|rcsb pdb:3GPW|rcsb pdb:4QVM|rcsb pdb:4QVN|rcsb pdb:4QVP|rcsb pdb:4QVQ|rcsb pdb:4QVV|rcsb pdb:4QVW|rcsb pdb:4QVY|rcsb pdb:4QW0|rcsb pdb:4QW1|rcsb pdb:4QW3|rcsb pdb:4QW4|rcsb pdb:4QW5|rcsb pdb:4QW6|rcsb pdb:4QW7|rcsb pdb:4QWF|rcsb pdb:4QWG|rcsb pdb:4QWI|rcsb pdb:4QWJ|rcsb pdb:4QWK|rcsb pdb:4QWL|rcsb pdb:4QWR|rcsb pdb:4QWS|rcsb pdb:4QWU|rcsb pdb:4QWX|rcsb pdb:4QXJ|rcsb pdb:4QZ0|rcsb pdb:4QZ1|rcsb pdb:4QZ2|rcsb pdb:4QZ3|rcsb pdb:4QZ4|rcsb pdb:4QZ5|rcsb pdb:4QZ6|rcsb pdb:4QZ7|rcsb pdb:4QZW|rcsb pdb:4QZX|rcsb pdb:4QZZ|rcsb pdb:4R00|rcsb pdb:4R02|rcsb pdb:4R17|rcsb pdb:4R18|rcsb pdb:4RUR|rcsb pdb:4V7O|rcsb pdb:4X6Z|rcsb pdb:4Y69|rcsb pdb:4Y6A|rcsb pdb:4Y6V|rcsb pdb:4Y6Z|rcsb pdb:4Y70|rcsb pdb:4Y74|rcsb pdb:4Y75|rcsb pdb:4Y77|rcsb pdb:4Y78|rcsb pdb:4Y7W|rcsb pdb:5LTT|rcsb pdb:5M2B|rcsb pdb:5MP9|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5NIF|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6G7F|rcsb pdb:6G8M|rcsb pdb:6G8N|rcsb pdb:6GOP|rcsb pdb:6H39|rcsb pdb:6HTB|rcsb pdb:6HTC|rcsb pdb:6HTD|rcsb pdb:6HTP|rcsb pdb:6HTR|rcsb pdb:6HUB|rcsb pdb:6HUC|rcsb pdb:6HUQ|rcsb pdb:6HUU|rcsb pdb:6HUV|rcsb pdb:6HV3|rcsb pdb:6HV4|rcsb pdb:6HV5|rcsb pdb:6HV7|rcsb pdb:6HVA|rcsb pdb:6HVR|rcsb pdb:6HVS|rcsb pdb:6HVT|rcsb pdb:6HVU|rcsb pdb:6HVV|rcsb pdb:5L5S|rcsb pdb:5L5T|rcsb pdb:5L5U|rcsb pdb:5L5V|rcsb pdb:5L5W|rcsb pdb:5L5X|rcsb pdb:5L5Y|rcsb pdb:5L5Z|rcsb pdb:5L60|rcsb pdb:5L61|rcsb pdb:5L62|rcsb pdb:5L63|rcsb pdb:5L64|rcsb pdb:5L65|rcsb pdb:5L66|rcsb pdb:5L67|rcsb pdb:5L68|rcsb pdb:5L69|rcsb pdb:5L6A|rcsb pdb:5L6B|rcsb pdb:5L6C|rcsb pdb:5LAI|rcsb pdb:5LAJ|rcsb pdb:6HVW|rcsb pdb:6HVX|rcsb pdb:6HVY|rcsb pdb:6HW0|rcsb pdb:6HW3|rcsb pdb:6HW4|rcsb pdb:6HW5|rcsb pdb:6HW6|rcsb pdb:6HW7|rcsb pdb:6HW8|rcsb pdb:6HW9|rcsb pdb:6HWA|rcsb pdb:6HWB|rcsb pdb:6HWC|rcsb pdb:6HWD|rcsb pdb:6HWE|rcsb pdb:6HWF|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2X|rcsb pdb:6J30|rcsb pdb:6ZOU|rcsb pdb:6ZP6|rcsb pdb:6ZP8|rcsb pdb:7LS5|rcsb pdb:7LS6|rcsb pdb:7LSX|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|rcsb pdb:6J2Q|refseq:NP_014045.1|sgd:S000004931|mint:P40302|dip:DIP-1528N	-	-	crc64:C43CBCC1C6B9E39E	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:oEjzTzRRvj9ygqEj2pca6MxK1Jo9606	rogid:C9GPb0JAklkBz0t/YYqRMNEiQss559292	intact-crc:0057286CD9AB30EF|rigid:l/M0DjcolNXCiU1n3A7/37FZ5p4	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P40454	uniprotkb:P14373	intact:EBI-25278|uniprotkb:D6VVD4|ensemblfungi:YIL153W	intact:EBI-719493|uniprotkb:A2BE15|uniprotkb:Q5RJA8|uniprotkb:Q5ST26|uniprotkb:Q6LA73|uniprotkb:Q6NXR9|uniprotkb:Q9BZY6|uniprotkb:Q9UJL3|ensembl:ENSP00000383555|ensembl:ENSP00000392787|ensembl:ENSP00000405229|ensembl:ENSP00000414793|ensembl:ENSP00000366404	psi-mi:ptpa1_yeast(display_long)|uniprotkb:YIL153W(locus name)|uniprotkb:RRD1(gene name)|psi-mi:RRD1(display_short)|uniprotkb:NCS1(gene name synonym)|uniprotkb:YPA1(gene name synonym)|uniprotkb:Peptidyl-prolyl cis-trans isomerase PTPA-1(gene name synonym)|uniprotkb:Phosphotyrosyl phosphatase activator 1(gene name synonym)	psi-mi:tri27_human(display_long)|uniprotkb:TRIM27(gene name)|psi-mi:TRIM27(display_short)|uniprotkb:RNF76(gene name synonym)|uniprotkb:RFP(gene name synonym)|uniprotkb:Ret finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 27(gene name synonym)|uniprotkb:RING finger protein 76(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM27(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549868|imex:IM-24995-3038	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012113.1|sgd:S000001415|mint:P40454|dip:DIP-5663N|ensemblfungi:YIL153W(gene)|ensemblfungi:YIL153W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006914"(autophagy)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008160"(protein tyrosine phosphatase activator activity)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0043618"(regulation of transcription from RNA polymerase II promoter in response to stress)|interpro:IPR004327(Phosphotyrosyl phosphatase activator, PTPA)|interpro:IPR037218|interpro:IPR043170|rcsb pdb:2IXO|rcsb pdb:2IXP	refseq:NP_006501.1|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0090281"(negative regulation of calcium ion import)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR020457|interpro:IPR035791|interpro:IPR043136|mint:P14373|reactome:R-HSA-3232142|reactome:R-HSA-9635465|reactome:R-HSA-8948751|ensembl:ENSG00000204713(gene)|ensembl:ENSG00000215641(gene)|ensembl:ENSG00000229006(gene)|ensembl:ENSG00000234495(gene)|ensembl:ENSG00000237071(gene)|ensembl:ENST00000377199(transcript)|ensembl:ENST00000400720(transcript)|ensembl:ENST00000431123(transcript)|ensembl:ENST00000435528(transcript)|ensembl:ENST00000437160(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001650"(fibrillar center)|go:"GO:0002820"(negative regulation of adaptive immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:It2q8WlpmvLEZ1fqpRF5Fypw9Q4559292	rogid:dsfH5OUghD8KSaTz1SFw9OYVTK49606	intact-crc:A155B90438F57F34|rigid:FT90KDDa2w97Bz5XrnlMMA3S8so	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P19012	uniprotkb:P40454	intact:EBI-739566|uniprotkb:Q53XV8|uniprotkb:Q9BUG4|uniprotkb:B3KQY1|uniprotkb:B3KRA2|uniprotkb:E0CX14|ensembl:ENSP00000254043|ensembl:ENSP00000377546	intact:EBI-25278|uniprotkb:D6VVD4|ensemblfungi:YIL153W	psi-mi:k1c15_human(display_long)|uniprotkb:KRT15(gene name)|psi-mi:KRT15(display_short)|uniprotkb:KRTB(gene name synonym)|uniprotkb:Cytokeratin-15(gene name synonym)|uniprotkb:Keratin-15(gene name synonym)	psi-mi:ptpa1_yeast(display_long)|uniprotkb:YIL153W(locus name)|uniprotkb:RRD1(gene name)|psi-mi:RRD1(display_short)|uniprotkb:NCS1(gene name synonym)|uniprotkb:YPA1(gene name synonym)|uniprotkb:Peptidyl-prolyl cis-trans isomerase PTPA-1(gene name synonym)|uniprotkb:Phosphotyrosyl phosphatase activator 1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549864|imex:IM-24995-3037	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002266.2|ensembl:ENSG00000171346(gene)|ensembl:ENST00000254043(transcript)|ensembl:ENST00000393976(transcript)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0008544"(epidermis development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097110"(scaffold protein binding)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR039008|mint:P19012|reactome:R-HSA-6805567|reactome:R-HSA-6809371	refseq:NP_012113.1|sgd:S000001415|mint:P40454|dip:DIP-5663N|ensemblfungi:YIL153W(gene)|ensemblfungi:YIL153W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006914"(autophagy)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008160"(protein tyrosine phosphatase activator activity)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0043618"(regulation of transcription from RNA polymerase II promoter in response to stress)|interpro:IPR004327(Phosphotyrosyl phosphatase activator, PTPA)|interpro:IPR037218|interpro:IPR043170|rcsb pdb:2IXO|rcsb pdb:2IXP	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:WrZQBYQvrWcfrR5ojWXrXp6spPE9606	rogid:It2q8WlpmvLEZ1fqpRF5Fypw9Q4559292	intact-crc:96527057C48064BA|rigid:aA/Wb4gvWPLiwm3Mr6RMszphK/8	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P40454	uniprotkb:P35638	intact:EBI-25278|uniprotkb:D6VVD4|ensemblfungi:YIL153W	intact:EBI-742651|ensembl:ENSP00000340671|ensembl:ENSP00000447188|ensembl:ENSP00000494844|uniprotkb:F8VS99	psi-mi:ptpa1_yeast(display_long)|uniprotkb:YIL153W(locus name)|uniprotkb:RRD1(gene name)|psi-mi:RRD1(display_short)|uniprotkb:NCS1(gene name synonym)|uniprotkb:YPA1(gene name synonym)|uniprotkb:Peptidyl-prolyl cis-trans isomerase PTPA-1(gene name synonym)|uniprotkb:Phosphotyrosyl phosphatase activator 1(gene name synonym)	psi-mi:ddit3_human(display_long)|uniprotkb:CHOP10(gene name synonym)|uniprotkb:C/EBP-homologous protein(gene name synonym)|uniprotkb:DDIT3(gene name)|psi-mi:DDIT3(display_short)|uniprotkb:CHOP(gene name synonym)|uniprotkb:GADD153(gene name synonym)|uniprotkb:Growth arrest and DNA damage-inducible protein GADD153(gene name synonym)|uniprotkb:C/EBP-homologous protein 10(gene name synonym)|uniprotkb:C/EBP zeta(gene name synonym)|uniprotkb:CCAAT/enhancer-binding protein homologous protein(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549860|imex:IM-24995-3036	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012113.1|sgd:S000001415|mint:P40454|dip:DIP-5663N|ensemblfungi:YIL153W(gene)|ensemblfungi:YIL153W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006914"(autophagy)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008160"(protein tyrosine phosphatase activator activity)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0043618"(regulation of transcription from RNA polymerase II promoter in response to stress)|interpro:IPR004327(Phosphotyrosyl phosphatase activator, PTPA)|interpro:IPR037218|interpro:IPR043170|rcsb pdb:2IXO|rcsb pdb:2IXP	refseq:NP_001181986.1|refseq:NP_004074.2|refseq:NP_001181982.1|refseq:NP_001181983.1|refseq:NP_001181984.1|ensembl:ENSG00000175197(gene)|go:"GO:0001955"(blood vessel maturation)|ensembl:ENST00000346473(transcript)|ensembl:ENST00000547303(transcript)|ensembl:ENST00000623876(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003677"(DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032792"(negative regulation of CREB transcription factor activity)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0036488"(CHOP-C/EBP complex)|go:"GO:0036499"(PERK-mediated unfolded protein response)|go:"GO:0036500"(ATF6-mediated unfolded protein response)|go:"GO:0042594"(response to starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0032713"(negative regulation of interleukin-4 production)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006983"(ER overload response)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0007049"(cell cycle)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008140"(cAMP response element binding protein binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0005737"(cytoplasm)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0005770"(late endosome)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032700"(negative regulation of interleukin-17 production)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0072655"(establishment of protein localization to mitochondrion)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0140416"(transcription regulator inhibitor activity)|go:"GO:1902237"(positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903026"(negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990442"(intrinsic apoptotic signaling pathway in response to nitrosative stress)|go:"GO:1990617"(CHOP-ATF4 complex)|go:"GO:1990622"(CHOP-ATF3 complex)|go:"GO:2000016"(negative regulation of determination of dorsal identity)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR016670(DNA damage-inducible transcript 3)|mint:P35638|reactome:R-HSA-380994|reactome:R-HSA-381183|reactome:R-HSA-9614657|reactome:R-HSA-9633012|reactome:R-HSA-9648895|go:"GO:0043618"(regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045662"(negative regulation of myoblast differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|dip:DIP-41589N	-	-	crc64:31905293FB1FBBE2	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:It2q8WlpmvLEZ1fqpRF5Fypw9Q4559292	rogid:xyMsMwPwid+S2IYb3H0K0pnUc309606	intact-crc:DFE23175FD1C4FE5|rigid:Jatb23/ICmSYg9k66GVVJQSkuTs	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P40368	uniprotkb:P37198	intact:EBI-12331|ensemblfungi:YJL061W|uniprotkb:D6VWC1	intact:EBI-347978|intact:EBI-28983799|ensembl:ENSP00000305503|ensembl:ENSP00000407331|ensembl:ENSP00000471191|ensembl:ENSP00000473192|uniprotkb:Q6GTM2|uniprotkb:Q503A4|uniprotkb:Q96C43|uniprotkb:Q9NSL1|uniprotkb:B3KWU5	psi-mi:nup82_yeast(display_long)|uniprotkb:NUP82(gene name)|psi-mi:NUP82(display_short)|uniprotkb:YJL061W(locus name)|uniprotkb:J1135(orf name)|uniprotkb:HRB187(orf name)|uniprotkb:Nuclear pore protein NUP82(gene name synonym)	psi-mi:nup62_human(display_long)|uniprotkb:NUP62(gene name)|psi-mi:NUP62(display_short)|uniprotkb:62 kDa nucleoporin(gene name synonym)|uniprotkb:Nucleoporin Nup62(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549856|imex:IM-24995-3035	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012474.1|sgd:S000003597|ensemblfungi:YJL061W(gene)|ensemblfungi:YJL061W_mRNA(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0005634"(nucleus)|interpro:IPR037700|rcsb pdb:3PBP|rcsb pdb:3TKN|go:"GO:0005643"(nuclear pore)|go:"GO:0005829"(cytosol)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0044612"(nuclear pore linkers)|go:"GO:0044614"(nuclear pore cytoplasmic filaments)|mint:P40368|dip:DIP-913N	refseq:NP_714941.1|ensembl:ENSG00000213024(gene)|ensembl:ENST00000352066(transcript)|ensembl:ENST00000422090(transcript)|ensembl:ENST00000596217(transcript)|ensembl:ENST00000597029(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005642"(annulate lamellae)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007100"(mitotic centrosome separation)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007569"(cell aging)|go:"GO:0008219"(cell death)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0003682"(chromatin binding)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0019894"(kinesin binding)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042306"(regulation of protein import into nucleus)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043069"(negative regulation of programmed cell death)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045742"(positive regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046578"(regulation of Ras protein signal transduction)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0046601"(positive regulation of centriole replication)|go:"GO:0051028"(mRNA transport)|go:"GO:0051425"(PTB domain binding)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0072686"(mitotic spindle)|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|go:"GO:0090543"(Flemming body)|go:"GO:0098534"(centriole assembly)|go:"GO:1903438"(positive regulation of mitotic cytokinetic process)|go:"GO:1904781"(positive regulation of protein localization to centrosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR007758(Nucleoporin, Nsp1-like, C-terminal)|interpro:IPR026010|interpro:IPR033072|mint:P37198|rcsb pdb:2H4D|rcsb pdb:5IJN|rcsb pdb:5IJO|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|refseq:NP_714940.1|refseq:NP_001180286.1|refseq:NP_036478.2|refseq:NP_057637.2|ensembl:ENSP00000305503|ensembl:ENSP00000407331|ensembl:ENSP00000471191|ensembl:ENSP00000473192|dip:DIP-29749N	-	crc64:C379B5E111E26B50	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:g1+jqOMmde8phrNI9H7nFlXwjH0559292	rogid:v7mvKvTtVEnLMwcpUZIcdAzge009606	intact-crc:AD7B354354B53219|rigid:RwOsFdGv+DFarKE9DT5kv5U33iw	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P40354	uniprotkb:A2A369	intact:EBI-12280|ensemblfungi:YJR062C|uniprotkb:D6VWN3	intact:EBI-11530808|ensembl:ENSP00000371766	psi-mi:nta1_yeast(display_long)|uniprotkb:J1742(orf name)|uniprotkb:YJR062C(locus name)|uniprotkb:NTA1(gene name)|psi-mi:NTA1(display_short)	psi-mi:a2a369_human(display_long)|uniprotkb:DOCK8(gene name)|psi-mi:DOCK8(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549852|imex:IM-24995-3034	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YJR062C(gene)|ensemblfungi:YJR062C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0008418"(protein-N-terminal asparagine amidohydrolase activity)|go:"GO:0030163"(protein catabolic process)|go:"GO:0031365"(N-terminal protein amino acid modification)|go:"GO:0070773"(protein-N-terminal glutamine amidohydrolase activity)|interpro:IPR003010(Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase)|interpro:IPR036526|interpro:IPR039703|refseq:NP_012596.3|sgd:S000003823|dip:DIP-6478N	ensembl:ENSG00000107099(gene)|ensembl:ENST00000382329(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0007264"(small GTPase mediated signal transduction)|interpro:IPR010703(Dedicator of cytokinesis)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026791|interpro:IPR027007|interpro:IPR027357|interpro:IPR035892|interpro:IPR043161|interpro:IPR043162	-	crc64:E6259FBBFB25A889	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:WuneoUOKjrppTwFurxcO41hR/W0559292	rogid:Sa5ulmmVxrpxZ+GAhN64RAHXYdk9606	intact-crc:10A9EB848912A805|rigid:hW09oO4w8ZshylXet9c+t1cQ05Q	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O95073-2	uniprotkb:P40302	intact:EBI-10696047	intact:EBI-13955|ensemblfungi:YMR314W|uniprotkb:D6W0E1	psi-mi:o95073-2(display_long)|uniprotkb:FSBP(gene name)|psi-mi:FSBP(display_short)	psi-mi:psa6_yeast(display_long)|uniprotkb:PRE5(gene name)|psi-mi:PRE5(display_short)|uniprotkb:YMR314W(locus name)|uniprotkb:YM9924.06(orf name)|uniprotkb:Proteasome component PRE5(gene name synonym)|uniprotkb:Macropain subunit PRE5(gene name synonym)|uniprotkb:Proteinase YSCE subunit PRE5(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit PRE5(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549828|imex:IM-24995-3028	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-1059030(isoform-parent)|uniprotkb:O95073-2(isoform-parent)	rcsb pdb:4Y8T|rcsb pdb:4Y8U|rcsb pdb:4Y9Y|rcsb pdb:4Y9Z|rcsb pdb:4YA0|rcsb pdb:4YA1|rcsb pdb:4YA2|rcsb pdb:4YA3|rcsb pdb:4YA4|rcsb pdb:4YA5|rcsb pdb:4Y7X|rcsb pdb:4Y7Y|rcsb pdb:4Y80|rcsb pdb:4Y81|rcsb pdb:4Y82|rcsb pdb:4Y84|rcsb pdb:4Y8G|rcsb pdb:4Y8H|rcsb pdb:4Y8I|rcsb pdb:4Y8J|rcsb pdb:4Y8K|rcsb pdb:4Y8L|rcsb pdb:4Y8M|rcsb pdb:4Y8N|rcsb pdb:4Y8O|rcsb pdb:4Y8P|rcsb pdb:4Y8Q|rcsb pdb:4Y8R|rcsb pdb:4Y8S|rcsb pdb:5FG7|rcsb pdb:5FG9|rcsb pdb:5FGA|rcsb pdb:4YA7|rcsb pdb:4YA9|rcsb pdb:4Z1L|rcsb pdb:5A5B|rcsb pdb:5AHJ|rcsb pdb:5BOU|rcsb pdb:5BXL|rcsb pdb:5BXN|rcsb pdb:5CGF|rcsb pdb:5CGG|rcsb pdb:5CGH|rcsb pdb:5CGI|rcsb pdb:5CZ4|rcsb pdb:5CZ5|rcsb pdb:5CZ6|rcsb pdb:5CZ7|rcsb pdb:5CZ8|rcsb pdb:5CZ9|rcsb pdb:5CZA|rcsb pdb:5D0S|rcsb pdb:5D0T|rcsb pdb:5D0V|rcsb pdb:5D0W|rcsb pdb:5D0X|rcsb pdb:5D0Z|rcsb pdb:5DKI|rcsb pdb:5DKJ|rcsb pdb:5FGD|rcsb pdb:3HYE|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:3MG0|rcsb pdb:3MG4|rcsb pdb:3MG6|rcsb pdb:3MG7|rcsb pdb:3MG8|rcsb pdb:3NZJ|rcsb pdb:3NZW|rcsb pdb:3NZX|rcsb pdb:3OEU|rcsb pdb:3OEV|rcsb pdb:3OKJ|rcsb pdb:3SDI|rcsb pdb:3SDK|rcsb pdb:3SHJ|rcsb pdb:3TDD|rcsb pdb:3UN4|rcsb pdb:3UN8|rcsb pdb:3WXR|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:4EU2|rcsb pdb:4FZC|rcsb pdb:4FZG|rcsb pdb:4G4S|rcsb pdb:4GK7|rcsb pdb:4HNP|rcsb pdb:4HRC|rcsb pdb:4HRD|rcsb pdb:4INR|rcsb pdb:4INT|rcsb pdb:4INU|rcsb pdb:4J70|rcsb pdb:4JSQ|rcsb pdb:4JSU|rcsb pdb:4JT0|rcsb pdb:4LQI|rcsb pdb:4LTC|rcsb pdb:4NNN|rcsb pdb:4NNW|rcsb pdb:4NO1|rcsb pdb:4NO6|rcsb pdb:4NO8|rcsb pdb:4NO9|rcsb pdb:5FGE|rcsb pdb:5FGF|rcsb pdb:5FGG|rcsb pdb:5FGH|rcsb pdb:5FGI|rcsb pdb:5FHS|rcsb pdb:5JHR|rcsb pdb:5JHS|rcsb pdb:5L52|rcsb pdb:5L54|rcsb pdb:5L55|rcsb pdb:5L5A|rcsb pdb:5L5B|rcsb pdb:5L5D|rcsb pdb:5L5E|rcsb pdb:5L5F|rcsb pdb:5L5H|rcsb pdb:5L5I|rcsb pdb:5L5J|rcsb pdb:5L5O|rcsb pdb:5L5P|rcsb pdb:5L5Q|rcsb pdb:5L5R|rcsb pdb:4Q1S|rcsb pdb:4QBY|rcsb pdb:4QLQ|rcsb pdb:4QLS|rcsb pdb:4QLT|rcsb pdb:4QLU|rcsb pdb:4QLV|rcsb pdb:4QUX|rcsb pdb:4QUY|rcsb pdb:4QV0|rcsb pdb:4QV1|rcsb pdb:4QV3|rcsb pdb:4QV4|rcsb pdb:4QV5|rcsb pdb:4QV6|rcsb pdb:4QV7|rcsb pdb:4QV8|rcsb pdb:4QV9|rcsb pdb:4QVL|ensemblfungi:YMR314W(gene)|ensemblfungi:YMR314W_mRNA(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0042175"(nuclear outer membrane-endoplasmic reticulum membrane network)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR035144|rcsb pdb:1FNT|rcsb pdb:1G0U|rcsb pdb:1G65|rcsb pdb:1JD2|rcsb pdb:1RYP|rcsb pdb:1Z7Q|rcsb pdb:2F16|rcsb pdb:2FAK|rcsb pdb:2GPL|rcsb pdb:2ZCY|rcsb pdb:3BDM|rcsb pdb:3D29|rcsb pdb:3DY3|rcsb pdb:3DY4|rcsb pdb:3E47|rcsb pdb:3GPJ|rcsb pdb:3GPT|rcsb pdb:3GPW|rcsb pdb:4QVM|rcsb pdb:4QVN|rcsb pdb:4QVP|rcsb pdb:4QVQ|rcsb pdb:4QVV|rcsb pdb:4QVW|rcsb pdb:4QVY|rcsb pdb:4QW0|rcsb pdb:4QW1|rcsb pdb:4QW3|rcsb pdb:4QW4|rcsb pdb:4QW5|rcsb pdb:4QW6|rcsb pdb:4QW7|rcsb pdb:4QWF|rcsb pdb:4QWG|rcsb pdb:4QWI|rcsb pdb:4QWJ|rcsb pdb:4QWK|rcsb pdb:4QWL|rcsb pdb:4QWR|rcsb pdb:4QWS|rcsb pdb:4QWU|rcsb pdb:4QWX|rcsb pdb:4QXJ|rcsb pdb:4QZ0|rcsb pdb:4QZ1|rcsb pdb:4QZ2|rcsb pdb:4QZ3|rcsb pdb:4QZ4|rcsb pdb:4QZ5|rcsb pdb:4QZ6|rcsb pdb:4QZ7|rcsb pdb:4QZW|rcsb pdb:4QZX|rcsb pdb:4QZZ|rcsb pdb:4R00|rcsb pdb:4R02|rcsb pdb:4R17|rcsb pdb:4R18|rcsb pdb:4RUR|rcsb pdb:4V7O|rcsb pdb:4X6Z|rcsb pdb:4Y69|rcsb pdb:4Y6A|rcsb pdb:4Y6V|rcsb pdb:4Y6Z|rcsb pdb:4Y70|rcsb pdb:4Y74|rcsb pdb:4Y75|rcsb pdb:4Y77|rcsb pdb:4Y78|rcsb pdb:4Y7W|rcsb pdb:5LTT|rcsb pdb:5M2B|rcsb pdb:5MP9|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5NIF|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6G7F|rcsb pdb:6G8M|rcsb pdb:6G8N|rcsb pdb:6GOP|rcsb pdb:6H39|rcsb pdb:6HTB|rcsb pdb:6HTC|rcsb pdb:6HTD|rcsb pdb:6HTP|rcsb pdb:6HTR|rcsb pdb:6HUB|rcsb pdb:6HUC|rcsb pdb:6HUQ|rcsb pdb:6HUU|rcsb pdb:6HUV|rcsb pdb:6HV3|rcsb pdb:6HV4|rcsb pdb:6HV5|rcsb pdb:6HV7|rcsb pdb:6HVA|rcsb pdb:6HVR|rcsb pdb:6HVS|rcsb pdb:6HVT|rcsb pdb:6HVU|rcsb pdb:6HVV|rcsb pdb:5L5S|rcsb pdb:5L5T|rcsb pdb:5L5U|rcsb pdb:5L5V|rcsb pdb:5L5W|rcsb pdb:5L5X|rcsb pdb:5L5Y|rcsb pdb:5L5Z|rcsb pdb:5L60|rcsb pdb:5L61|rcsb pdb:5L62|rcsb pdb:5L63|rcsb pdb:5L64|rcsb pdb:5L65|rcsb pdb:5L66|rcsb pdb:5L67|rcsb pdb:5L68|rcsb pdb:5L69|rcsb pdb:5L6A|rcsb pdb:5L6B|rcsb pdb:5L6C|rcsb pdb:5LAI|rcsb pdb:5LAJ|rcsb pdb:6HVW|rcsb pdb:6HVX|rcsb pdb:6HVY|rcsb pdb:6HW0|rcsb pdb:6HW3|rcsb pdb:6HW4|rcsb pdb:6HW5|rcsb pdb:6HW6|rcsb pdb:6HW7|rcsb pdb:6HW8|rcsb pdb:6HW9|rcsb pdb:6HWA|rcsb pdb:6HWB|rcsb pdb:6HWC|rcsb pdb:6HWD|rcsb pdb:6HWE|rcsb pdb:6HWF|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2X|rcsb pdb:6J30|rcsb pdb:6ZOU|rcsb pdb:6ZP6|rcsb pdb:6ZP8|rcsb pdb:7LS5|rcsb pdb:7LS6|rcsb pdb:7LSX|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|rcsb pdb:6J2Q|refseq:NP_014045.1|sgd:S000004931|mint:P40302|dip:DIP-1528N	-	isoform-comment:No experimental confirmation available.	crc64:C43CBCC1C6B9E39E	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:j4ktleFZa7rAjRFENAKAGdAd+Fs9606	rogid:C9GPb0JAklkBz0t/YYqRMNEiQss559292	intact-crc:66F5C5646E917CFA|rigid:/4/t9j6pG8UVth1hTqK8+YOMRxc	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P40325	uniprotkb:E9PFK9	intact:EBI-23614|uniprotkb:D6VV46|ensemblfungi:YGR268C	intact:EBI-11523104|ensembl:ENSP00000403429	psi-mi:hua1_yeast(display_long)|uniprotkb:HUA1(gene name)|psi-mi:HUA1(display_short)|uniprotkb:YGR268C(locus name)	psi-mi:e9pfk9_human(display_long)|uniprotkb:RABGEF1(gene name)|psi-mi:RABGEF1(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549844|imex:IM-24995-3032	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003500|refseq:NP_011784.3|dip:DIP-1987N|ensemblfungi:YGR268C(gene)|ensemblfungi:YGR268C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|interpro:IPR038910	ensembl:ENSG00000154710(gene)|ensembl:ENST00000439720(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|interpro:IPR002653(Zinc finger, A20-type)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR037191|interpro:IPR041545	-	crc64:78029FD484168793	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:xliNG9XUWbYRd0Nbu+xzCgxNrAs559292	rogid:JDHW8cuCB2z39j6a+LlkARnLfYo9606	intact-crc:220AA162ACB8EDDD|rigid:HAvEPRZLIiZozCqVw7mjCvpShpU	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O00308	uniprotkb:P40325	intact:EBI-743923|uniprotkb:H3BRF3|uniprotkb:Q6ZTQ5|uniprotkb:A6NEP1|uniprotkb:Q96CZ2|uniprotkb:Q9BWN6|uniprotkb:B2R706|uniprotkb:B4DTL5|uniprotkb:F5H213|uniprotkb:I3RSG8|ensembl:ENSP00000352069	intact:EBI-23614|uniprotkb:D6VV46|ensemblfungi:YGR268C	psi-mi:wwp2_human(display_long)|uniprotkb:WW domain-containing protein 2(gene name synonym)|uniprotkb:Atrophin-1-interacting protein 2(gene name synonym)|uniprotkb:WWP2(gene name)|psi-mi:WWP2(display_short)|uniprotkb:HECT-type E3 ubiquitin transferase WWP2(gene name synonym)	psi-mi:hua1_yeast(display_long)|uniprotkb:HUA1(gene name)|psi-mi:HUA1(display_short)|uniprotkb:YGR268C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549840|imex:IM-24995-3031	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_008945.2|refseq:NP_001257383.1|refseq:NP_001257384.1|refseq:XP_011521125.1|refseq:XP_011521127.1|refseq:XP_011521128.1|refseq:NP_001257382.1|refseq:NP_955456.1|refseq:XP_016878368.1|refseq:XP_016878369.1|refseq:XP_016878370.1|ensembl:ENSG00000198373(gene)|ensembl:ENST00000359154(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006858"(extracellular transport)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032410"(negative regulation of transporter activity)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0051224"(negative regulation of protein transport)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:1901016"(regulation of potassium ion transmembrane transporter activity)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000569(HECT)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR024928|interpro:IPR035892|interpro:IPR035983|interpro:IPR036020|mint:O00308|rcsb pdb:4Y07|rcsb pdb:5TJ7|rcsb pdb:5TJ8|rcsb pdb:5TJQ|rcsb pdb:6J1Z|rcsb pdb:6RSS|reactome:R-HSA-8948751|reactome:R-HSA-9013406|reactome:R-HSA-9013409|reactome:R-HSA-9013420|reactome:R-HSA-9013507	sgd:S000003500|refseq:NP_011784.3|dip:DIP-1987N|ensemblfungi:YGR268C(gene)|ensemblfungi:YGR268C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|interpro:IPR038910	-	-	crc64:78029FD484168793	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Xj0Xssn75HP9sp/tHNe4n83eHPE9606	rogid:xliNG9XUWbYRd0Nbu+xzCgxNrAs559292	intact-crc:4F29F70275E906D3|rigid:YmFWIjYzfPfhf5yuAI2KMCmrd00	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P40325	uniprotkb:O75886	intact:EBI-23614|uniprotkb:D6VV46|ensemblfungi:YGR268C	intact:EBI-373258|uniprotkb:Q7LDQ0|uniprotkb:Q9UF58|uniprotkb:A8K8A0|uniprotkb:D3DPA1|ensembl:ENSP00000263904	psi-mi:hua1_yeast(display_long)|uniprotkb:HUA1(gene name)|psi-mi:HUA1(display_short)|uniprotkb:YGR268C(locus name)	psi-mi:stam2_human(display_long)|uniprotkb:STAM2(gene name)|psi-mi:STAM2(display_short)|uniprotkb:HBP(gene name synonym)|uniprotkb:Hrs-binding protein(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549836|imex:IM-24995-3030	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003500|refseq:NP_011784.3|dip:DIP-1987N|ensemblfungi:YGR268C(gene)|ensemblfungi:YGR268C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|interpro:IPR038910	refseq:NP_005834.4|ensembl:ENSG00000115145(gene)|ensembl:ENST00000263904(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0015031"(protein transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0031901"(early endosome membrane)|go:"GO:0033565"(ESCRT-0 complex)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR001452(Src homology-3)|interpro:IPR002014(VHS)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR035675|interpro:IPR036028|mint:O75886|rcsb pdb:1X2Q|rcsb pdb:1X5B|rcsb pdb:2L0T|rcsb pdb:5CRV|rcsb pdb:5IXF|reactome:R-HSA-182971|reactome:R-HSA-5689880|reactome:R-HSA-6807004|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8875360|reactome:R-HSA-9013420|reactome:R-HSA-917729	-	crc64:78029FD484168793	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:xliNG9XUWbYRd0Nbu+xzCgxNrAs559292	rogid:e5brcAWS5So29SdnZV3cAm/dZAk9606	intact-crc:6DBE7B3D7C6A41EB|rigid:0Ll8W5USnqPLfOJFREug13vfCME	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P40303	uniprotkb:Q08379	intact:EBI-13980|ensemblfungi:YOL038W|uniprotkb:D6W229	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	psi-mi:psa4_yeast(display_long)|uniprotkb:PRE6(gene name)|psi-mi:PRE6(display_short)|uniprotkb:YOL038W(locus name)|uniprotkb:Proteasome component PRE6(gene name synonym)|uniprotkb:Macropain subunit PRE6(gene name synonym)|uniprotkb:Proteinase YSCE subunit PRE6(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit PRE6(gene name synonym)	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549832|imex:IM-24995-3029	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YOL038W(gene)|ensemblfungi:YOL038W_mRNA(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0042175"(nuclear outer membrane-endoplasmic reticulum membrane network)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023332|interpro:IPR029055|rcsb pdb:1FNT|rcsb pdb:1G0U|rcsb pdb:1G65|rcsb pdb:1JD2|rcsb pdb:1RYP|rcsb pdb:1Z7Q|rcsb pdb:2F16|rcsb pdb:2FAK|rcsb pdb:2GPL|rcsb pdb:2ZCY|rcsb pdb:3BDM|rcsb pdb:3D29|rcsb pdb:3DY3|rcsb pdb:3DY4|rcsb pdb:4QZ1|rcsb pdb:4QZ2|rcsb pdb:4QZ3|rcsb pdb:4QZ4|rcsb pdb:4QZ5|rcsb pdb:4QZ6|rcsb pdb:4QZ7|rcsb pdb:4QZW|rcsb pdb:4QZX|rcsb pdb:4QZZ|rcsb pdb:4R00|rcsb pdb:4R02|rcsb pdb:4R17|rcsb pdb:4R18|rcsb pdb:4RUR|rcsb pdb:4V7O|rcsb pdb:4X6Z|rcsb pdb:4Y69|rcsb pdb:4Y6A|rcsb pdb:4Y6V|rcsb pdb:4Y6Z|rcsb pdb:4Y70|rcsb pdb:4Y74|rcsb pdb:4Y75|rcsb pdb:4Y77|rcsb pdb:4Y78|rcsb pdb:4Y7W|rcsb pdb:4Y7X|rcsb pdb:4Y7Y|rcsb pdb:4Y80|rcsb pdb:4QZ0|rcsb pdb:4Y81|rcsb pdb:4Y82|rcsb pdb:4Y84|rcsb pdb:4Y8H|rcsb pdb:4Y8I|rcsb pdb:4Y8J|rcsb pdb:4Y8K|rcsb pdb:4Y8L|rcsb pdb:4Y8M|rcsb pdb:4Y8N|rcsb pdb:4Y8O|rcsb pdb:4Y8P|rcsb pdb:4Y8Q|rcsb pdb:4Y8R|rcsb pdb:4Y8S|rcsb pdb:4Y8T|rcsb pdb:4Y8U|rcsb pdb:4Y9Y|rcsb pdb:4Y9Z|rcsb pdb:4YA0|rcsb pdb:4YA1|rcsb pdb:4YA2|rcsb pdb:4YA3|rcsb pdb:4Y8G|rcsb pdb:4YA4|rcsb pdb:4YA5|rcsb pdb:4YA7|rcsb pdb:4YA9|rcsb pdb:4Z1L|rcsb pdb:5A5B|rcsb pdb:5AHJ|rcsb pdb:5BOU|rcsb pdb:5BXN|rcsb pdb:5CGF|rcsb pdb:5CGG|rcsb pdb:5CGH|rcsb pdb:5CGI|rcsb pdb:5CZ4|rcsb pdb:5CZ5|rcsb pdb:5CZ6|rcsb pdb:5CZ7|rcsb pdb:5CZ8|rcsb pdb:5CZ9|rcsb pdb:5CZA|rcsb pdb:5D0S|rcsb pdb:5D0T|rcsb pdb:5D0V|rcsb pdb:5D0W|rcsb pdb:5D0X|rcsb pdb:5BXL|rcsb pdb:5D0Z|rcsb pdb:5DKI|rcsb pdb:5DKJ|rcsb pdb:5FG9|rcsb pdb:5FGA|rcsb pdb:5FGD|rcsb pdb:5FGE|rcsb pdb:5FGF|rcsb pdb:5FGG|rcsb pdb:5FGH|rcsb pdb:5FG7|rcsb pdb:5FGI|rcsb pdb:5FHS|rcsb pdb:5JHR|rcsb pdb:5JHS|rcsb pdb:5L52|rcsb pdb:5L54|rcsb pdb:5L55|rcsb pdb:5L5A|rcsb pdb:5L5B|rcsb pdb:5L5D|rcsb pdb:5L5E|rcsb pdb:5L5F|rcsb pdb:5L5H|rcsb pdb:5L5I|rcsb pdb:5L5J|rcsb pdb:5L5O|rcsb pdb:5L5P|rcsb pdb:5L5Q|rcsb pdb:5L5R|rcsb pdb:5L5S|rcsb pdb:5L5T|rcsb pdb:5L5U|rcsb pdb:5L5V|rcsb pdb:5L5W|rcsb pdb:5L5X|rcsb pdb:5L5Y|rcsb pdb:5L5Z|rcsb pdb:5L60|rcsb pdb:5L61|rcsb pdb:5L62|rcsb pdb:5L63|rcsb pdb:5L64|rcsb pdb:5L65|rcsb pdb:5L66|rcsb pdb:5L67|rcsb pdb:5L68|rcsb pdb:5L69|rcsb pdb:5L6A|rcsb pdb:5L6B|rcsb pdb:5LAI|rcsb pdb:5LAJ|rcsb pdb:5LTT|rcsb pdb:5M2B|rcsb pdb:5MP9|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5NIF|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:5L6C|rcsb pdb:6FVW|rcsb pdb:6FVY|rcsb pdb:6G7F|rcsb pdb:6G8M|rcsb pdb:6G8N|rcsb pdb:6GOP|rcsb pdb:6H39|rcsb pdb:6HTB|rcsb pdb:6HTC|rcsb pdb:6HTD|rcsb pdb:6HTP|rcsb pdb:6HTR|rcsb pdb:6HUB|rcsb pdb:6HUC|rcsb pdb:6HUQ|rcsb pdb:6FVX|rcsb pdb:6HUU|rcsb pdb:6HUV|rcsb pdb:6HV3|rcsb pdb:6HV4|rcsb pdb:6HV5|rcsb pdb:6HV7|rcsb pdb:6HVA|rcsb pdb:6HVR|rcsb pdb:6HVS|rcsb pdb:6HVT|rcsb pdb:6HVU|rcsb pdb:6HVV|rcsb pdb:6HVW|rcsb pdb:6HVX|rcsb pdb:6HVY|rcsb pdb:6HW0|rcsb pdb:6HW3|rcsb pdb:6HW4|rcsb pdb:6HW5|rcsb pdb:6HW6|rcsb pdb:6HW7|rcsb pdb:6HW8|rcsb pdb:6HW9|rcsb pdb:6HWA|rcsb pdb:6HWB|rcsb pdb:6HWC|rcsb pdb:6HWE|rcsb pdb:6HWF|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6HWD|rcsb pdb:6J2X|rcsb pdb:6J30|rcsb pdb:6ZOU|rcsb pdb:6ZP6|rcsb pdb:6ZP8|rcsb pdb:7LS5|rcsb pdb:7LS6|rcsb pdb:7LSX|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|rcsb pdb:3E47|rcsb pdb:3GPJ|rcsb pdb:3GPT|rcsb pdb:3GPW|rcsb pdb:3HYE|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:3MG0|rcsb pdb:3MG4|rcsb pdb:3MG6|rcsb pdb:3MG7|rcsb pdb:3MG8|rcsb pdb:3NZJ|rcsb pdb:3NZW|rcsb pdb:3NZX|rcsb pdb:3OEU|rcsb pdb:3OEV|rcsb pdb:3OKJ|rcsb pdb:3SDI|rcsb pdb:3SDK|rcsb pdb:3SHJ|rcsb pdb:3TDD|rcsb pdb:3UN4|rcsb pdb:3UN8|rcsb pdb:3WXR|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:4EU2|rcsb pdb:4FZC|rcsb pdb:4FZG|rcsb pdb:4G4S|rcsb pdb:4GK7|rcsb pdb:4HRC|rcsb pdb:4HRD|rcsb pdb:4INR|rcsb pdb:4INT|rcsb pdb:4INU|rcsb pdb:4J70|rcsb pdb:4JSQ|rcsb pdb:4JSU|rcsb pdb:4JT0|rcsb pdb:4LQI|rcsb pdb:4LTC|rcsb pdb:4NNN|rcsb pdb:4NNW|rcsb pdb:4NO1|rcsb pdb:4HNP|rcsb pdb:4NO6|rcsb pdb:4NO8|rcsb pdb:4NO9|rcsb pdb:4Q1S|rcsb pdb:4QBY|rcsb pdb:4QLQ|rcsb pdb:4QLS|rcsb pdb:4QLT|rcsb pdb:4QLU|rcsb pdb:4QLV|rcsb pdb:4QUX|rcsb pdb:4QUY|rcsb pdb:4QV1|rcsb pdb:4QV3|rcsb pdb:4QV4|rcsb pdb:4QV5|rcsb pdb:4QV6|rcsb pdb:4QV7|rcsb pdb:4QV8|rcsb pdb:4QV9|rcsb pdb:4QVL|rcsb pdb:4QVM|rcsb pdb:4QVN|rcsb pdb:4QVP|rcsb pdb:4QVQ|rcsb pdb:4QVV|rcsb pdb:4QVW|rcsb pdb:4QVY|rcsb pdb:4QW0|rcsb pdb:4QW1|rcsb pdb:4QW3|rcsb pdb:4QW4|rcsb pdb:4QW5|rcsb pdb:4QW6|rcsb pdb:4QW7|rcsb pdb:4QWF|rcsb pdb:4QWG|rcsb pdb:4QV0|rcsb pdb:4QWI|rcsb pdb:4QWJ|rcsb pdb:4QWK|rcsb pdb:4QWL|rcsb pdb:4QWR|rcsb pdb:4QWS|rcsb pdb:4QWU|rcsb pdb:4QWX|rcsb pdb:4QXJ|refseq:NP_014604.1|sgd:S000005398|mint:P40303|dip:DIP-4844N	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N	-	crc64:73AEE63B836E618A	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2017/05/26	rogid:G8IQr0G8FhiWc0DYUlh3vecHQsU559292	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	intact-crc:31DFEF657E827D4D|rigid:ISh8x9sKRumZ+m46aodWbR7ddg8	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O14641	uniprotkb:P40325	intact:EBI-740850|ensembl:ENSP00000005340|uniprotkb:Q53XM0|uniprotkb:D3DTN3	intact:EBI-23614|uniprotkb:D6VV46|ensemblfungi:YGR268C	psi-mi:dvl2_human(display_long)|uniprotkb:DSH homolog 2(gene name synonym)|uniprotkb:DVL2(gene name)|psi-mi:DVL2(display_short)	psi-mi:hua1_yeast(display_long)|uniprotkb:HUA1(gene name)|psi-mi:HUA1(display_short)|uniprotkb:YGR268C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549848|imex:IM-24995-3033	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004413.1|ensembl:ENSG00000004975(gene)|ensembl:ENST00000005340(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005109"(frizzled binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0007507"(heart development)|go:"GO:0016235"(aggresome)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044340"(canonical Wnt signaling pathway involved in regulation of cell proliferation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0150012"(positive regulation of neuron projection arborization)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008341(Dishevelled-2 region)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:O14641|rcsb pdb:2REY|rcsb pdb:3CBX|rcsb pdb:3CBY|rcsb pdb:3CBZ|rcsb pdb:3CC0|rcsb pdb:4WIP|rcsb pdb:5LNP|rcsb pdb:5SUY|rcsb pdb:5SUZ|rcsb pdb:6IW3|rcsb pdb:6JCK|reactome:R-HSA-201681|reactome:R-HSA-201688|reactome:R-HSA-2028269|reactome:R-HSA-4086400|reactome:R-HSA-4608870|reactome:R-HSA-4641258|reactome:R-HSA-4641262|reactome:R-HSA-5099900|reactome:R-HSA-5368598|reactome:R-HSA-5663220|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9673324|ensembl:ENSP00000005340|dip:DIP-34433N	sgd:S000003500|refseq:NP_011784.3|dip:DIP-1987N|ensemblfungi:YGR268C(gene)|ensemblfungi:YGR268C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|interpro:IPR038910	-	-	crc64:78029FD484168793	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:2Vdc8oRnT4Mz/j+EXQXrL3AszOc9606	rogid:xliNG9XUWbYRd0Nbu+xzCgxNrAs559292	intact-crc:CF159169D3DD93AF|rigid:jooQ7Ge+kEOIeZpv8+uU/HTP9Gw	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P40482	uniprotkb:O43186	intact:EBI-16592|ensemblfungi:YIL109C|uniprotkb:D6VVH8	intact:EBI-748171|uniprotkb:Q0QD45|ensembl:ENSP00000221996|ensembl:ENSP00000445565	psi-mi:sec24_yeast(display_long)|uniprotkb:SEC24(gene name)|psi-mi:SEC24(display_short)|uniprotkb:Abnormal nuclear morphology 1(gene name synonym)|uniprotkb:ANU1(gene name synonym)|uniprotkb:YIL109C(locus name)	psi-mi:crx_human(display_long)|uniprotkb:CRX(gene name)|psi-mi:CRX(display_short)|uniprotkb:CORD2(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549916|imex:IM-24995-3050	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012157.3|ensemblfungi:YIL109C(gene)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016236"(macroautophagy)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0070971"(endoplasmic reticulum exit site)|ensemblfungi:YIL109C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0090110"(COPII-coated vesicle cargo loading)|interpro:IPR006895(Zinc finger, Sec23/Sec24-type)|interpro:IPR006896(Sec23/Sec24 trunk region)|interpro:IPR006900(Sec23/Sec24 helical region)|interpro:IPR007123(Gelsolin region)|interpro:IPR012990(Sec23/Sec24 beta-sandwich)|interpro:IPR029006|interpro:IPR036174|interpro:IPR036175|interpro:IPR036180|go:"GO:0000149"(SNARE binding)|go:"GO:0000329"(fungal-type vacuole membrane)|interpro:IPR036465|interpro:IPR041742|rcsb pdb:1M2V|rcsb pdb:1PCX|rcsb pdb:1PD0|rcsb pdb:1PD1|rcsb pdb:4BZI|rcsb pdb:6GNI|rcsb pdb:6ZGA|reactome:R-SCE-204005|reactome:R-SCE-5694530|reactome:R-SCE-983170|go:"GO:0005048"(signal sequence binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|sgd:S000001371|dip:DIP-2233N|mint:P40482	refseq:NP_000545.1|ensembl:ENSG00000105392(gene)|ensembl:ENST00000221996(transcript)|ensembl:ENST00000539067(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007601"(visual perception)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050896"(response to stimulus)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013851(Transcription factor Otx, C-terminal)|interpro:IPR017970	-	crc64:35E2BDD24CC75899	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:e7ekVFzZJMZvfRUZ9Q2jDQ/hvs0559292	rogid:v/bkO/0iLzq1Q2HtieWQQ40RF9M9606	intact-crc:934553259657E0A0|rigid:9K4xOQkvhSsK+w7VgSKN3FAe70Y	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:G5E962	uniprotkb:P40481	intact:EBI-11525615|ensembl:ENSP00000328177	intact:EBI-25180|uniprotkb:D6VVH7|ensemblfungi:YIL110W	psi-mi:g5e962_human(display_long)|uniprotkb:hCG_1644200(orf name)|uniprotkb:MAGEA11(gene name)|psi-mi:MAGEA11(display_short)	psi-mi:hpm1_yeast(display_long)|uniprotkb:MNI1(gene name synonym)|uniprotkb:YIL110W(locus name)|uniprotkb:HPM1(gene name)|psi-mi:HPM1(display_short)|uniprotkb:Mitotic exit network interactor 1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549912|imex:IM-24995-3049	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001011544.1|ensembl:ENSG00000185247(gene)|ensembl:ENST00000333104(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016604"(nuclear body)|interpro:IPR002190(MAGE protein)|interpro:IPR021072|interpro:IPR030099|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899	refseq:NP_012156.1|sgd:S000001372|dip:DIP-4710N|ensemblfungi:YIL110W(gene)|ensemblfungi:YIL110W_mRNA(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0018064"(protein-L-histidine N-tele-methyltransferase activity)|go:"GO:0042038"(peptidyl-histidine methylation, to form tele-methylhistidine)|go:"GO:0045903"(positive regulation of translational fidelity)|interpro:IPR019410	-	-	crc64:C90C67433B5BCA7A	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:sVB0aA6yibWUx/d2SE+pwpKKgtI9606	rogid:hoAVij8oaANAGDSPMwh+IW39rn8559292	intact-crc:8757D40CB9259822|rigid:mtUIaU+R0fXUT35sYcjU6W1thdo	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P40460	uniprotkb:O14964	intact:EBI-25247|uniprotkb:D6VVE3|ensemblfungi:YIL144W	intact:EBI-740220|uniprotkb:Q9NR36|ensembl:ENSP00000331201|ensembl:ENSP00000504106	psi-mi:ndc80_yeast(display_long)|uniprotkb:NDC80(gene name)|psi-mi:NDC80(display_short)|uniprotkb:80 kDa spindle component protein(gene name synonym)|uniprotkb:HEC1(gene name synonym)|uniprotkb:Nuclear division cycle protein 80(gene name synonym)|uniprotkb:TID3(gene name synonym)|uniprotkb:Two-hybrid interaction with DMC1 protein 3(gene name synonym)|uniprotkb:YIL144W(locus name)	psi-mi:hgs_human(display_long)|uniprotkb:Protein pp110(gene name synonym)|uniprotkb:Hrs(gene name synonym)|uniprotkb:HGS(gene name)|psi-mi:HGS(display_short)|uniprotkb:HRS(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549908|imex:IM-24995-3048	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000001406|refseq:NP_012122.3|mint:P40460|dip:DIP-818N|ensemblfungi:YIL144W(gene)|ensemblfungi:YIL144W_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0007059"(chromosome segregation)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0042802"(identical protein binding)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|interpro:IPR005550(HEC/Ndc80p)|interpro:IPR038273|interpro:IPR040967|rcsb pdb:5TCS|rcsb pdb:5TD8|rcsb pdb:7KDF	refseq:NP_004703.1|dip:DIP-29050N|ensembl:ENSG00000185359(gene)|ensembl:ENST00000329138(transcript)|ensembl:ENST00000676546(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0007165"(signal transduction)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010324"(membrane invagination)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010642"(negative regulation of platelet-derived growth factor receptor signaling pathway)|go:"GO:0016197"(endosomal transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032585"(multivesicular body membrane)|go:"GO:0033565"(ESCRT-0 complex)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043405"(regulation of MAP kinase activity)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072657"(protein localization to membrane)|go:"GO:0097013"(phagocytic vesicle lumen)|go:"GO:1903543"(positive regulation of exosomal secretion)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR002014(VHS)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017073(Ubiquitin binding protein, Hrs/VPS27)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR024641|mint:O14964|rcsb pdb:2D3G|rcsb pdb:3F1I|rcsb pdb:3OBQ|rcsb pdb:3ZYQ|rcsb pdb:4AVX|reactome:R-HSA-182971|reactome:R-HSA-432720|reactome:R-HSA-5689880|reactome:R-HSA-6807004|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8875360|reactome:R-HSA-9013420|reactome:R-HSA-917729|reactome:R-HSA-9635644|reactome:R-HSA-9636383|reactome:R-HSA-9706019	-	crc64:7DBC492227A80093	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:ZrT7N4pBKz6upSglhGhOqgeoAYw559292	rogid:z/AnREuqEpyJ9/Zj6JFCJCJem1I9606	intact-crc:C7D9F89197DCD66C|rigid:q6e4XfVFovWkoLeZrXGfwCTLUAU	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q08379	uniprotkb:P40455	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	intact:EBI-25274|uniprotkb:D6VVD5|ensemblfungi:YIL152W	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:yip2_yeast(display_long)|uniprotkb:YIL152W(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549904|imex:IM-24995-3047	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N	sgd:S000001414|refseq:NP_012114.1|mint:P40455|dip:DIP-2047N|ensemblfungi:YIL152W(gene)|ensemblfungi:YIL152W_mRNA(transcript)	-	-	crc64:07550E3F491F53A8	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2017/05/26	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	rogid:t5hCm1ck6kpFUxpEd8CsyLrHbEw559292	intact-crc:AF9541516E6E36E8|rigid:X+W6oH3jCPQgWHpfShH+ReGKEHU	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O14641	uniprotkb:P40455	intact:EBI-740850|ensembl:ENSP00000005340|uniprotkb:Q53XM0|uniprotkb:D3DTN3	intact:EBI-25274|uniprotkb:D6VVD5|ensemblfungi:YIL152W	psi-mi:dvl2_human(display_long)|uniprotkb:DSH homolog 2(gene name synonym)|uniprotkb:DVL2(gene name)|psi-mi:DVL2(display_short)	psi-mi:yip2_yeast(display_long)|uniprotkb:YIL152W(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549900|imex:IM-24995-3046	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004413.1|ensembl:ENSG00000004975(gene)|ensembl:ENST00000005340(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005109"(frizzled binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0007507"(heart development)|go:"GO:0016235"(aggresome)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044340"(canonical Wnt signaling pathway involved in regulation of cell proliferation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0150012"(positive regulation of neuron projection arborization)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008341(Dishevelled-2 region)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:O14641|rcsb pdb:2REY|rcsb pdb:3CBX|rcsb pdb:3CBY|rcsb pdb:3CBZ|rcsb pdb:3CC0|rcsb pdb:4WIP|rcsb pdb:5LNP|rcsb pdb:5SUY|rcsb pdb:5SUZ|rcsb pdb:6IW3|rcsb pdb:6JCK|reactome:R-HSA-201681|reactome:R-HSA-201688|reactome:R-HSA-2028269|reactome:R-HSA-4086400|reactome:R-HSA-4608870|reactome:R-HSA-4641258|reactome:R-HSA-4641262|reactome:R-HSA-5099900|reactome:R-HSA-5368598|reactome:R-HSA-5663220|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9673324|ensembl:ENSP00000005340|dip:DIP-34433N	sgd:S000001414|refseq:NP_012114.1|mint:P40455|dip:DIP-2047N|ensemblfungi:YIL152W(gene)|ensemblfungi:YIL152W_mRNA(transcript)	-	-	crc64:07550E3F491F53A8	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:2Vdc8oRnT4Mz/j+EXQXrL3AszOc9606	rogid:t5hCm1ck6kpFUxpEd8CsyLrHbEw559292	intact-crc:9C0204C652E6BB2E|rigid:6KNcHMZ71nkyff8OYwPyQlhJ8vA	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P40454	uniprotkb:P15531	intact:EBI-25278|uniprotkb:D6VVD4|ensemblfungi:YIL153W	intact:EBI-741141|ensembl:ENSP00000376892|uniprotkb:Q6FGK3|uniprotkb:Q86XQ2|uniprotkb:Q9UDJ6	psi-mi:ptpa1_yeast(display_long)|uniprotkb:YIL153W(locus name)|uniprotkb:RRD1(gene name)|psi-mi:RRD1(display_short)|uniprotkb:NCS1(gene name synonym)|uniprotkb:YPA1(gene name synonym)|uniprotkb:Peptidyl-prolyl cis-trans isomerase PTPA-1(gene name synonym)|uniprotkb:Phosphotyrosyl phosphatase activator 1(gene name synonym)	psi-mi:ndka_human(display_long)|uniprotkb:Tumor metastatic process-associated protein(gene name synonym)|uniprotkb:Metastasis inhibition factor nm23(gene name synonym)|uniprotkb:Granzyme A-activated DNase(gene name synonym)|uniprotkb:NME1(gene name)|psi-mi:NME1(display_short)|uniprotkb:NDPKA(gene name synonym)|uniprotkb:NM23(gene name synonym)|uniprotkb:NM23-H1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549872|imex:IM-24995-3039	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012113.1|sgd:S000001415|mint:P40454|dip:DIP-5663N|ensemblfungi:YIL153W(gene)|ensemblfungi:YIL153W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006914"(autophagy)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008160"(protein tyrosine phosphatase activator activity)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0043618"(regulation of transcription from RNA polymerase II promoter in response to stress)|interpro:IPR004327(Phosphotyrosyl phosphatase activator, PTPA)|interpro:IPR037218|interpro:IPR043170|rcsb pdb:2IXO|rcsb pdb:2IXP	refseq:NP_000260.1|refseq:NP_937818.1|ensembl:ENSG00000239672(gene)|ensembl:ENST00000393196(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0002762"(negative regulation of myeloid leukocyte differentiation)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004536"(deoxyribonuclease activity)|go:"GO:0004550"(nucleoside diphosphate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0006183"(GTP biosynthetic process)|go:"GO:0006228"(UTP biosynthetic process)|go:"GO:0006241"(CTP biosynthetic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007595"(lactation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014075"(response to amine)|go:"GO:0016020"(membrane)|go:"GO:0019215"(intermediate filament binding)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051591"(response to cAMP)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071398"(cellular response to fatty acid)|interpro:IPR001564(Nucleoside diphosphate kinase, core)|go:"GO:0019899"(enzyme binding)|interpro:IPR023005|go:"GO:0021766"(hippocampus development)|interpro:IPR034907|interpro:IPR036850|mint:P15531|go:"GO:0030154"(cell differentiation)|go:"GO:0032587"(ruffle membrane)|rcsb pdb:1JXV|rcsb pdb:1UCN|go:"GO:0033574"(response to testosterone)|go:"GO:0035690"|rcsb pdb:2HVD|rcsb pdb:2HVE|rcsb pdb:3L7U|rcsb pdb:4ENO|rcsb pdb:5UI4|reactome:R-HSA-499943|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043024"(ribosomal small subunit binding)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|dip:DIP-39164N	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:It2q8WlpmvLEZ1fqpRF5Fypw9Q4559292	rogid:Ut4gK1Xq786CaZzvqdS1eiU5op89606	intact-crc:BB43CBC498B5F718|rigid:kIJctXvQmDZgb6/CHGf4titKCK0	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P40454	uniprotkb:O96006	intact:EBI-25278|uniprotkb:D6VVD4|ensemblfungi:YIL153W	intact:EBI-740037|uniprotkb:Q96BY4|ensembl:ENSP00000370616|ensembl:ENSP00000370620|ensembl:ENSP00000370621|ensembl:ENSP00000498725	psi-mi:ptpa1_yeast(display_long)|uniprotkb:YIL153W(locus name)|uniprotkb:RRD1(gene name)|psi-mi:RRD1(display_short)|uniprotkb:NCS1(gene name synonym)|uniprotkb:YPA1(gene name synonym)|uniprotkb:Peptidyl-prolyl cis-trans isomerase PTPA-1(gene name synonym)|uniprotkb:Phosphotyrosyl phosphatase activator 1(gene name synonym)	psi-mi:zbed1_human(display_long)|uniprotkb:ZBED1(gene name)|psi-mi:ZBED1(display_short)|uniprotkb:ALTE(gene name synonym)|uniprotkb:DREF(gene name synonym)|uniprotkb:KIAA0785(gene name synonym)|uniprotkb:TRAMP(gene name synonym)|uniprotkb:dREF homolog(gene name synonym)|uniprotkb:Putative Ac-like transposable element(gene name synonym)|uniprotkb:DNA replication-related element-binding factor(gene name synonym)|uniprotkb:Zinc finger BED domain-containing protein 1(gene name synonym)|uniprotkb:hDREF(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549892|imex:IM-24995-3044	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012113.1|sgd:S000001415|mint:P40454|dip:DIP-5663N|ensemblfungi:YIL153W(gene)|ensemblfungi:YIL153W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006914"(autophagy)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008160"(protein tyrosine phosphatase activator activity)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0043618"(regulation of transcription from RNA polymerase II promoter in response to stress)|interpro:IPR004327(Phosphotyrosyl phosphatase activator, PTPA)|interpro:IPR037218|interpro:IPR043170|rcsb pdb:2IXO|rcsb pdb:2IXP	refseq:NP_001164606.1|refseq:NP_001164607.1|refseq:NP_004720.1|ensembl:ENSG00000214717(gene)|ensembl:ENST00000381218(transcript)|ensembl:ENST00000381222(transcript)|ensembl:ENST00000381223(transcript)|ensembl:ENST00000652001(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0031965"(nuclear membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044828"(negative regulation by host of viral genome replication)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0061665"(SUMO ligase activity)|go:"GO:1990466"(protein autosumoylation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003656(Zinc finger, BED-type predicted)|interpro:IPR008906(HAT dimerisation)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR036236|mint:O96006|rcsb pdb:2CT5|reactome:R-HSA-4551638|go:"GO:0005813"(centrosome)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016605"(PML body)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:It2q8WlpmvLEZ1fqpRF5Fypw9Q4559292	rogid:jl97ZV2Kz5YAmQKktWt/wk7OkRw9606	intact-crc:67F079AF39370516|rigid:ZLGqKYVB2VfqEsWkHOH+FzojGYI	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P40454	uniprotkb:G5E962	intact:EBI-25278|uniprotkb:D6VVD4|ensemblfungi:YIL153W	intact:EBI-11525615|ensembl:ENSP00000328177	psi-mi:ptpa1_yeast(display_long)|uniprotkb:YIL153W(locus name)|uniprotkb:RRD1(gene name)|psi-mi:RRD1(display_short)|uniprotkb:NCS1(gene name synonym)|uniprotkb:YPA1(gene name synonym)|uniprotkb:Peptidyl-prolyl cis-trans isomerase PTPA-1(gene name synonym)|uniprotkb:Phosphotyrosyl phosphatase activator 1(gene name synonym)	psi-mi:g5e962_human(display_long)|uniprotkb:hCG_1644200(orf name)|uniprotkb:MAGEA11(gene name)|psi-mi:MAGEA11(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549888|imex:IM-24995-3043	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012113.1|sgd:S000001415|mint:P40454|dip:DIP-5663N|ensemblfungi:YIL153W(gene)|ensemblfungi:YIL153W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006914"(autophagy)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008160"(protein tyrosine phosphatase activator activity)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0043618"(regulation of transcription from RNA polymerase II promoter in response to stress)|interpro:IPR004327(Phosphotyrosyl phosphatase activator, PTPA)|interpro:IPR037218|interpro:IPR043170|rcsb pdb:2IXO|rcsb pdb:2IXP	refseq:NP_001011544.1|ensembl:ENSG00000185247(gene)|ensembl:ENST00000333104(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016604"(nuclear body)|interpro:IPR002190(MAGE protein)|interpro:IPR021072|interpro:IPR030099|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:It2q8WlpmvLEZ1fqpRF5Fypw9Q4559292	rogid:sVB0aA6yibWUx/d2SE+pwpKKgtI9606	intact-crc:F2F15F2B06D31A6C|rigid:KsVct/YV1zMOa+Ebr+FAG0MIZPE	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P40454	uniprotkb:O76083-2	intact:EBI-25278|uniprotkb:D6VVD4|ensemblfungi:YIL153W	intact:EBI-11524542|ensembl:ENSP00000335242	psi-mi:ptpa1_yeast(display_long)|uniprotkb:YIL153W(locus name)|uniprotkb:RRD1(gene name)|psi-mi:RRD1(display_short)|uniprotkb:NCS1(gene name synonym)|uniprotkb:YPA1(gene name synonym)|uniprotkb:Peptidyl-prolyl cis-trans isomerase PTPA-1(gene name synonym)|uniprotkb:Phosphotyrosyl phosphatase activator 1(gene name synonym)	psi-mi:o76083-2(display_long)|uniprotkb:PDE9A(gene name)|psi-mi:PDE9A(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549884|imex:IM-24995-3042	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012113.1|sgd:S000001415|mint:P40454|dip:DIP-5663N|ensemblfungi:YIL153W(gene)|ensemblfungi:YIL153W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006914"(autophagy)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008160"(protein tyrosine phosphatase activator activity)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0043618"(regulation of transcription from RNA polymerase II promoter in response to stress)|interpro:IPR004327(Phosphotyrosyl phosphatase activator, PTPA)|interpro:IPR037218|interpro:IPR043170|rcsb pdb:2IXO|rcsb pdb:2IXP	intact:EBI-742764(isoform-parent)|ensembl:ENSG00000160191(gene)|ensembl:ENST00000335512(transcript)|uniprotkb:O76083-2(isoform-parent)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:It2q8WlpmvLEZ1fqpRF5Fypw9Q4559292	rogid:nTzgeYGOwTM/7VJUgxSnlnDiCFo9606	intact-crc:E03CA6FA6F548CB0|rigid:BXZw2vFztuNWbIemzOgAazbzMhk	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P38432	uniprotkb:P40454	intact:EBI-945751|uniprotkb:B2R931|ensembl:ENSP00000240316	intact:EBI-25278|uniprotkb:D6VVD4|ensemblfungi:YIL153W	psi-mi:coil_human(display_long)|uniprotkb:COIL(gene name)|psi-mi:COIL(display_short)|uniprotkb:CLN80(gene name synonym)|uniprotkb:p80-coilin(gene name synonym)	psi-mi:ptpa1_yeast(display_long)|uniprotkb:YIL153W(locus name)|uniprotkb:RRD1(gene name)|psi-mi:RRD1(display_short)|uniprotkb:NCS1(gene name synonym)|uniprotkb:YPA1(gene name synonym)|uniprotkb:Peptidyl-prolyl cis-trans isomerase PTPA-1(gene name synonym)|uniprotkb:Phosphotyrosyl phosphatase activator 1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549880|imex:IM-24995-3041	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004636.1|dip:DIP-38503N|ensembl:ENSG00000121058(gene)|ensembl:ENST00000240316(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0015030"(Cajal body)|go:"GO:0016020"(membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0030619"(U1 snRNA binding)|go:"GO:0030620"(U2 snRNA binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR024822|interpro:IPR031722|mint:P38432	refseq:NP_012113.1|sgd:S000001415|mint:P40454|dip:DIP-5663N|ensemblfungi:YIL153W(gene)|ensemblfungi:YIL153W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006914"(autophagy)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008160"(protein tyrosine phosphatase activator activity)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0043618"(regulation of transcription from RNA polymerase II promoter in response to stress)|interpro:IPR004327(Phosphotyrosyl phosphatase activator, PTPA)|interpro:IPR037218|interpro:IPR043170|rcsb pdb:2IXO|rcsb pdb:2IXP	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:hd5p6AbyA/GYNEeca99Mdb41qM09606	rogid:It2q8WlpmvLEZ1fqpRF5Fypw9Q4559292	intact-crc:0F35DC729F5AA1DB|rigid:9BOWBg6pGUDiRMnXq/IwLYKkyEQ	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P40454	uniprotkb:A2A369	intact:EBI-25278|uniprotkb:D6VVD4|ensemblfungi:YIL153W	intact:EBI-11530808|ensembl:ENSP00000371766	psi-mi:ptpa1_yeast(display_long)|uniprotkb:YIL153W(locus name)|uniprotkb:RRD1(gene name)|psi-mi:RRD1(display_short)|uniprotkb:NCS1(gene name synonym)|uniprotkb:YPA1(gene name synonym)|uniprotkb:Peptidyl-prolyl cis-trans isomerase PTPA-1(gene name synonym)|uniprotkb:Phosphotyrosyl phosphatase activator 1(gene name synonym)	psi-mi:a2a369_human(display_long)|uniprotkb:DOCK8(gene name)|psi-mi:DOCK8(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549876|imex:IM-24995-3040	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012113.1|sgd:S000001415|mint:P40454|dip:DIP-5663N|ensemblfungi:YIL153W(gene)|ensemblfungi:YIL153W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006914"(autophagy)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008160"(protein tyrosine phosphatase activator activity)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0043618"(regulation of transcription from RNA polymerase II promoter in response to stress)|interpro:IPR004327(Phosphotyrosyl phosphatase activator, PTPA)|interpro:IPR037218|interpro:IPR043170|rcsb pdb:2IXO|rcsb pdb:2IXP	ensembl:ENSG00000107099(gene)|ensembl:ENST00000382329(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0007264"(small GTPase mediated signal transduction)|interpro:IPR010703(Dedicator of cytokinesis)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026791|interpro:IPR027007|interpro:IPR027357|interpro:IPR035892|interpro:IPR043161|interpro:IPR043162	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:It2q8WlpmvLEZ1fqpRF5Fypw9Q4559292	rogid:Sa5ulmmVxrpxZ+GAhN64RAHXYdk9606	intact-crc:FADAAFA08CAB5C33|rigid:BRPqghNdVaxCkDOG5Xsw8yD+iLA	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P40454	uniprotkb:O15156-2	intact:EBI-25278|uniprotkb:D6VVD4|ensemblfungi:YIL153W	intact:EBI-11522250|ensembl:ENSP00000406286	psi-mi:ptpa1_yeast(display_long)|uniprotkb:YIL153W(locus name)|uniprotkb:RRD1(gene name)|psi-mi:RRD1(display_short)|uniprotkb:NCS1(gene name synonym)|uniprotkb:YPA1(gene name synonym)|uniprotkb:Peptidyl-prolyl cis-trans isomerase PTPA-1(gene name synonym)|uniprotkb:Phosphotyrosyl phosphatase activator 1(gene name synonym)	psi-mi:o15156-2(display_long)|uniprotkb:ZBTB7B(gene name)|psi-mi:ZBTB7B(display_short)|uniprotkb:Krueppel-related zinc finger protein cKrox(gene name synonym)|uniprotkb:T-helper-inducing POZ/Krueppel-like factor(gene name synonym)|uniprotkb:ZBTB15(gene name synonym)|uniprotkb:ZFP67(gene name synonym)|uniprotkb:ZNF857B(gene name synonym)|uniprotkb:Zinc finger and BTB domain-containing protein 15(gene name synonym)|uniprotkb:Zinc finger protein 67 homolog(gene name synonym)|uniprotkb:Zinc finger protein 857B(gene name synonym)|uniprotkb:Zinc finger protein Th-POK(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549896|imex:IM-24995-3045	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012113.1|sgd:S000001415|mint:P40454|dip:DIP-5663N|ensemblfungi:YIL153W(gene)|ensemblfungi:YIL153W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006914"(autophagy)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008160"(protein tyrosine phosphatase activator activity)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0043618"(regulation of transcription from RNA polymerase II promoter in response to stress)|interpro:IPR004327(Phosphotyrosyl phosphatase activator, PTPA)|interpro:IPR037218|interpro:IPR043170|rcsb pdb:2IXO|rcsb pdb:2IXP	intact:EBI-740434(isoform-parent)|ensembl:ENSG00000160685(gene)|ensembl:ENST00000417934(transcript)|uniprotkb:O15156-2(isoform-parent)	-	-	isoform-comment:No experimental confirmation available.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:It2q8WlpmvLEZ1fqpRF5Fypw9Q4559292	rogid:41NEFYyprTXI+fOHVFh78TPKF289606	intact-crc:712625B3284FC220|rigid:Mt7Tv9gZQn2oR/jTpxqKaeswQOg	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
intact:EBI-11531492	uniprotkb:P40554	-	intact:EBI-24940|uniprotkb:D6VVS2|ensemblfungi:YIL008W	psi-mi:znf3(display_short)|psi-mi:EBI-11531492(display_long)	psi-mi:urm1_yeast(display_long)|uniprotkb:YIL008W(locus name)|uniprotkb:URM1(gene name)|psi-mi:URM1(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549948|imex:IM-24995-3058	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	-	sgd:S000001270|refseq:NP_012258.3|dip:DIP-1894N|ensemblfungi:YIL008W(gene)|ensemblfungi:YIL008W_mRNA(transcript)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0002143"(tRNA wobble position uridine thiolation)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007114"(cell budding)|go:"GO:0031386"(protein tag)|go:"GO:0032447"(protein urmylation)|go:"GO:0034227"(tRNA thio-modification)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0097163"(sulfur carrier activity)|interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|interpro:IPR015221(Ubiquitin related modifier 1)|interpro:IPR016155(Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp)|rcsb pdb:2AX5|rcsb pdb:2PKO|rcsb pdb:2QJL	-	no-uniprot-update:	crc64:A15356D6C1B6B5BC	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:eSPiEBOxNojLEOXLwp/UY9zTIwo9606	rogid:JFW+GAegUnn1FQ2++OlVr9IbgBA559292	intact-crc:7346C367DD2B5626|rigid:YY/IMmZxhjIgmlUfYuA9YevnKM8	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P40507	uniprotkb:P15622-3	intact:EBI-25083|uniprotkb:D6VVK5|ensemblfungi:YIL079C	intact:EBI-10177272|ensembl:ENSP00000393442	psi-mi:air1_yeast(display_long)|uniprotkb:Arginine methyltransferase-interacting RING finger protein 1(gene name synonym)|uniprotkb:AIR1(gene name)|psi-mi:AIR1(display_short)|uniprotkb:YIL079C(locus name)	psi-mi:p15622-3(display_long)|uniprotkb:ZNF647(gene name synonym)|uniprotkb:Zinc finger protein 647(gene name synonym)|uniprotkb:ZNF250(gene name)|psi-mi:ZNF250(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549944|imex:IM-24995-3057	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012186.1|sgd:S000001341|mint:P40507|dip:DIP-2700N|ensemblfungi:YIL079C(gene)|ensemblfungi:YIL079C_mRNA(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031499"(TRAMP complex)|go:"GO:0043629"(ncRNA polyadenylation)|go:"GO:0071031"(nuclear mRNA surveillance of mRNA 3'-end processing)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071036"(nuclear polyadenylation-dependent snoRNA catabolic process)|go:"GO:0071037"(nuclear polyadenylation-dependent snRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071039"(nuclear polyadenylation-dependent CUT catabolic process)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR016713("Poly(A) polymerase complex, Air1/2")|interpro:IPR036875	ensembl:ENSG00000196150(gene)|ensembl:ENST00000417550(transcript)|intact:EBI-739678(isoform-parent)|uniprotkb:P15622-3(isoform-parent)	-	crc64:3CA920FA1204EC9C	isoform-comment:No experimental confirmation available.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:myPxXwP+mJgvoh50PLYk2Q3GMh4559292	rogid:4AVjeOREEATULMJWtdeZt7rhi889606	intact-crc:483470C8C2489FEB|rigid:Dk5IFw8zoK+HyqUvFGaAk0kqfz4	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P40507	uniprotkb:Q8N5R6	intact:EBI-25083|uniprotkb:D6VVK5|ensemblfungi:YIL079C	intact:EBI-740841|intact:EBI-953781|uniprotkb:B3KQ49|uniprotkb:A8K3U4|uniprotkb:A8MPQ6|uniprotkb:A8MV61|uniprotkb:A8MVU9|uniprotkb:Q9H5Q6|uniprotkb:Q8TAX6|intact:EBI-2320546|intact:EBI-11522976	psi-mi:air1_yeast(display_long)|uniprotkb:Arginine methyltransferase-interacting RING finger protein 1(gene name synonym)|uniprotkb:AIR1(gene name)|psi-mi:AIR1(display_short)|uniprotkb:YIL079C(locus name)	psi-mi:ccd33_human(display_long)|uniprotkb:CCDC33(gene name)|psi-mi:CCDC33(display_short)|uniprotkb:Cancer/testis antigen 61(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549940|imex:IM-24995-3056	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012186.1|sgd:S000001341|mint:P40507|dip:DIP-2700N|ensemblfungi:YIL079C(gene)|ensemblfungi:YIL079C_mRNA(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031499"(TRAMP complex)|go:"GO:0043629"(ncRNA polyadenylation)|go:"GO:0071031"(nuclear mRNA surveillance of mRNA 3'-end processing)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071036"(nuclear polyadenylation-dependent snoRNA catabolic process)|go:"GO:0071037"(nuclear polyadenylation-dependent snRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071039"(nuclear polyadenylation-dependent CUT catabolic process)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR016713("Poly(A) polymerase complex, Air1/2")|interpro:IPR036875	refseq:NP_079331.3|interpro:IPR000008(C2 calcium-dependent membrane targeting)|go:"GO:0005777"(peroxisome)|refseq:NP_001274110.1|refseq:NP_877592.2|mint:Q8N5R6|interpro:IPR035892|interpro:IPR039889	-	crc64:3CA920FA1204EC9C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2021/11/30	rogid:myPxXwP+mJgvoh50PLYk2Q3GMh4559292	rogid:eEIn7pQyfdHWx8TeLJpYy0i/gww9606	intact-crc:1522DE0EE8BE52E8|rigid:cim1x7HrbAQekz/HjixosQzWvzM	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P40482	uniprotkb:O76081-6	intact:EBI-16592|ensemblfungi:YIL109C|uniprotkb:D6VVH8	intact:EBI-10178530|ensembl:ENSP00000276500	psi-mi:sec24_yeast(display_long)|uniprotkb:SEC24(gene name)|psi-mi:SEC24(display_short)|uniprotkb:Abnormal nuclear morphology 1(gene name synonym)|uniprotkb:ANU1(gene name synonym)|uniprotkb:YIL109C(locus name)	psi-mi:o76081-6(display_long)|uniprotkb:RGS20(gene name)|psi-mi:RGS20(display_short)|uniprotkb:Gz-selective GTPase-activating protein(gene name synonym)|uniprotkb:RGSZ1(gene name synonym)|uniprotkb:Regulator of G-protein signaling Z1(gene name synonym)|uniprotkb:Regulator of Gz-selective protein signaling 1(gene name synonym)|uniprotkb:ZGAP1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549920|imex:IM-24995-3051	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012157.3|ensemblfungi:YIL109C(gene)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016236"(macroautophagy)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0070971"(endoplasmic reticulum exit site)|ensemblfungi:YIL109C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0090110"(COPII-coated vesicle cargo loading)|interpro:IPR006895(Zinc finger, Sec23/Sec24-type)|interpro:IPR006896(Sec23/Sec24 trunk region)|interpro:IPR006900(Sec23/Sec24 helical region)|interpro:IPR007123(Gelsolin region)|interpro:IPR012990(Sec23/Sec24 beta-sandwich)|interpro:IPR029006|interpro:IPR036174|interpro:IPR036175|interpro:IPR036180|go:"GO:0000149"(SNARE binding)|go:"GO:0000329"(fungal-type vacuole membrane)|interpro:IPR036465|interpro:IPR041742|rcsb pdb:1M2V|rcsb pdb:1PCX|rcsb pdb:1PD0|rcsb pdb:1PD1|rcsb pdb:4BZI|rcsb pdb:6GNI|rcsb pdb:6ZGA|reactome:R-SCE-204005|reactome:R-SCE-5694530|reactome:R-SCE-983170|go:"GO:0005048"(signal sequence binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|sgd:S000001371|dip:DIP-2233N|mint:P40482	intact:EBI-1052678(isoform-parent)|uniprotkb:O76081-6(isoform-parent)|ensembl:ENSG00000147509(gene)|ensembl:ENST00000276500(transcript)	-	crc64:35E2BDD24CC75899	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:e7ekVFzZJMZvfRUZ9Q2jDQ/hvs0559292	rogid:5ddWx+4uSAxIhugOqlfdCIOD8sM9606	intact-crc:C385FE945F119575|rigid:YhPTliygjtLXzPH62nXn2agvctI	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P40507	uniprotkb:P38159	intact:EBI-25083|uniprotkb:D6VVK5|ensemblfungi:YIL079C	intact:EBI-743526|ensembl:ENSP00000359645|uniprotkb:Q5JQ67|uniprotkb:Q969R3|uniprotkb:D3DWH0|uniprotkb:E9PG86|uniprotkb:Q8N8Y7|uniprotkb:B4E3U4	psi-mi:air1_yeast(display_long)|uniprotkb:Arginine methyltransferase-interacting RING finger protein 1(gene name synonym)|uniprotkb:AIR1(gene name)|psi-mi:AIR1(display_short)|uniprotkb:YIL079C(locus name)	psi-mi:rbmx_human(display_long)|uniprotkb:Glycoprotein p43(gene name synonym)|uniprotkb:RBMX(gene name)|psi-mi:RBMX(display_short)|uniprotkb:HNRPG(gene name synonym)|uniprotkb:RBMXP1(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein G(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549932|imex:IM-24995-3054	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012186.1|sgd:S000001341|mint:P40507|dip:DIP-2700N|ensemblfungi:YIL079C(gene)|ensemblfungi:YIL079C_mRNA(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031499"(TRAMP complex)|go:"GO:0043629"(ncRNA polyadenylation)|go:"GO:0071031"(nuclear mRNA surveillance of mRNA 3'-end processing)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071036"(nuclear polyadenylation-dependent snoRNA catabolic process)|go:"GO:0071037"(nuclear polyadenylation-dependent snRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071039"(nuclear polyadenylation-dependent CUT catabolic process)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR016713("Poly(A) polymerase complex, Air1/2")|interpro:IPR036875	ensembl:ENSG00000147274(gene)|ensembl:ENST00000320676(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000791"(euchromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0044530"(supraspliceosomal complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0006509"(membrane protein ectodomain proteolysis)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012604(RBM1CTR)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|mint:P38159|rcsb pdb:2MB0|rcsb pdb:2MKS|reactome:R-HSA-72163|reactome:R-HSA-72203|reactome:R-HSA-9013418|reactome:R-HSA-9013422|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273|refseq:NP_002130.2|refseq:NP_001158275.1|dip:DIP-34447N	-	crc64:3CA920FA1204EC9C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:myPxXwP+mJgvoh50PLYk2Q3GMh4559292	rogid:ocCkdy9PxjeVLUQf0tMVCEhFfO89606	intact-crc:1225BF6B318EB517|rigid:/BQgaVjBAPbAXp3cUMSPBC9hM5w	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P40507	uniprotkb:P07910-2	intact:EBI-25083|uniprotkb:D6VVK5|ensemblfungi:YIL079C	intact:EBI-5280084|ensembl:ENSP00000442816|ensembl:ENSP00000450544|ensembl:ENSP00000450725|ensembl:ENSP00000451176	psi-mi:air1_yeast(display_long)|uniprotkb:Arginine methyltransferase-interacting RING finger protein 1(gene name synonym)|uniprotkb:AIR1(gene name)|psi-mi:AIR1(display_short)|uniprotkb:YIL079C(locus name)	psi-mi:p07910-2(display_long)|uniprotkb:HNRNPC(gene name)|psi-mi:HNRNPC(display_short)|uniprotkb:HNRPC(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549928|imex:IM-24995-3053	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012186.1|sgd:S000001341|mint:P40507|dip:DIP-2700N|ensemblfungi:YIL079C(gene)|ensemblfungi:YIL079C_mRNA(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031499"(TRAMP complex)|go:"GO:0043629"(ncRNA polyadenylation)|go:"GO:0071031"(nuclear mRNA surveillance of mRNA 3'-end processing)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071036"(nuclear polyadenylation-dependent snoRNA catabolic process)|go:"GO:0071037"(nuclear polyadenylation-dependent snRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071039"(nuclear polyadenylation-dependent CUT catabolic process)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR016713("Poly(A) polymerase complex, Air1/2")|interpro:IPR036875	uniprotkb:P07910-2(isoform-parent)|intact:EBI-357966(isoform-parent)|ensembl:ENSG00000092199(gene)|ensembl:ENST00000430246(transcript)|ensembl:ENST00000553300(transcript)|ensembl:ENST00000554969(transcript)|ensembl:ENST00000556897(transcript)	-	crc64:3CA920FA1204EC9C	isoform-comment:Contains a phosphoserine at position 107. Contains a phosphoserine at position 108.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:myPxXwP+mJgvoh50PLYk2Q3GMh4559292	rogid:r7AhGozE3aHdynLr8DrXPRtOuyI9606	intact-crc:64224EE91E981ADD|rigid:Sc9prlxF38fvgxdgRooc5Z7hWGM	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O95273	uniprotkb:P40491	intact:EBI-748961|uniprotkb:A8K3Q0|uniprotkb:A8K3U2|uniprotkb:Q6ZQN9|uniprotkb:Q7Z519|uniprotkb:Q8NBS7|uniprotkb:Q8NBY2|uniprotkb:Q9NS19|uniprotkb:Q9NYH3|uniprotkb:Q9UHX9|ensembl:ENSP00000300213	intact:EBI-25141|uniprotkb:D6VVI9|ensemblfungi:YIL098C	psi-mi:ccdb1_human(display_long)|uniprotkb:Grap2 and cyclin-D-interacting protein(gene name synonym)|uniprotkb:Human homolog of Maid(gene name synonym)|uniprotkb:CCNDBP1(gene name)|psi-mi:CCNDBP1(display_short)|uniprotkb:DIP1(gene name synonym)|uniprotkb:GCIP(gene name synonym)|uniprotkb:HHM(gene name synonym)	psi-mi:fmc1_yeast(display_long)|uniprotkb:Formation of mitochondrial complexes protein 1(gene name synonym)|uniprotkb:YIL098C(locus name)|uniprotkb:FMC1(gene name)|psi-mi:FMC1(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549924|imex:IM-24995-3052	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_036274.3|ensembl:ENSG00000166946(gene)|ensembl:ENST00000300213(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0016604"(nuclear body)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR026907|mint:O95273|rcsb pdb:3AY5	sgd:S000001360|refseq:NP_012168.3|mint:P40491|dip:DIP-5652N|ensemblfungi:YIL098C(gene)|ensemblfungi:YIL098C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0016236"(macroautophagy)|go:"GO:0033615"(mitochondrial proton-transporting ATP synthase complex assembly)|interpro:IPR039196	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:Vi9aoFc+Mov6P3X6KGmsTxXqxvM9606	rogid:lGt1inZN/0++e/TWYR1mZnMBG2o559292	intact-crc:A3670766173944C1|rigid:xf9fPRteokFBvM531dSYRH/F6jU	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O14641	uniprotkb:P40507	intact:EBI-740850|ensembl:ENSP00000005340|uniprotkb:Q53XM0|uniprotkb:D3DTN3	intact:EBI-25083|uniprotkb:D6VVK5|ensemblfungi:YIL079C	psi-mi:dvl2_human(display_long)|uniprotkb:DSH homolog 2(gene name synonym)|uniprotkb:DVL2(gene name)|psi-mi:DVL2(display_short)	psi-mi:air1_yeast(display_long)|uniprotkb:Arginine methyltransferase-interacting RING finger protein 1(gene name synonym)|uniprotkb:AIR1(gene name)|psi-mi:AIR1(display_short)|uniprotkb:YIL079C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549936|imex:IM-24995-3055	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004413.1|ensembl:ENSG00000004975(gene)|ensembl:ENST00000005340(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005109"(frizzled binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0007507"(heart development)|go:"GO:0016235"(aggresome)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044340"(canonical Wnt signaling pathway involved in regulation of cell proliferation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0150012"(positive regulation of neuron projection arborization)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008341(Dishevelled-2 region)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:O14641|rcsb pdb:2REY|rcsb pdb:3CBX|rcsb pdb:3CBY|rcsb pdb:3CBZ|rcsb pdb:3CC0|rcsb pdb:4WIP|rcsb pdb:5LNP|rcsb pdb:5SUY|rcsb pdb:5SUZ|rcsb pdb:6IW3|rcsb pdb:6JCK|reactome:R-HSA-201681|reactome:R-HSA-201688|reactome:R-HSA-2028269|reactome:R-HSA-4086400|reactome:R-HSA-4608870|reactome:R-HSA-4641258|reactome:R-HSA-4641262|reactome:R-HSA-5099900|reactome:R-HSA-5368598|reactome:R-HSA-5663220|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9673324|ensembl:ENSP00000005340|dip:DIP-34433N	refseq:NP_012186.1|sgd:S000001341|mint:P40507|dip:DIP-2700N|ensemblfungi:YIL079C(gene)|ensemblfungi:YIL079C_mRNA(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031499"(TRAMP complex)|go:"GO:0043629"(ncRNA polyadenylation)|go:"GO:0071031"(nuclear mRNA surveillance of mRNA 3'-end processing)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071036"(nuclear polyadenylation-dependent snoRNA catabolic process)|go:"GO:0071037"(nuclear polyadenylation-dependent snRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071039"(nuclear polyadenylation-dependent CUT catabolic process)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR016713("Poly(A) polymerase complex, Air1/2")|interpro:IPR036875	-	-	crc64:3CA920FA1204EC9C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:2Vdc8oRnT4Mz/j+EXQXrL3AszOc9606	rogid:myPxXwP+mJgvoh50PLYk2Q3GMh4559292	intact-crc:0791006B3786EE4A|rigid:57oxXwgEOJrXbemx21HDveUyELo	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O14641	uniprotkb:P40956	intact:EBI-740850|ensembl:ENSP00000005340|uniprotkb:Q53XM0|uniprotkb:D3DTN3	intact:EBI-7968|uniprotkb:D6VTX2|ensemblfungi:YGL181W	psi-mi:dvl2_human(display_long)|uniprotkb:DSH homolog 2(gene name synonym)|uniprotkb:DVL2(gene name)|psi-mi:DVL2(display_short)	psi-mi:gts1_yeast(display_long)|uniprotkb:YGL181W(locus name)|uniprotkb:GTS1(gene name)|psi-mi:GTS1(display_short)|uniprotkb:LSR1(gene name synonym)|uniprotkb:Protein LSR1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549976|imex:IM-24995-3065	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004413.1|ensembl:ENSG00000004975(gene)|ensembl:ENST00000005340(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005109"(frizzled binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0007507"(heart development)|go:"GO:0016235"(aggresome)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044340"(canonical Wnt signaling pathway involved in regulation of cell proliferation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0150012"(positive regulation of neuron projection arborization)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008341(Dishevelled-2 region)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:O14641|rcsb pdb:2REY|rcsb pdb:3CBX|rcsb pdb:3CBY|rcsb pdb:3CBZ|rcsb pdb:3CC0|rcsb pdb:4WIP|rcsb pdb:5LNP|rcsb pdb:5SUY|rcsb pdb:5SUZ|rcsb pdb:6IW3|rcsb pdb:6JCK|reactome:R-HSA-201681|reactome:R-HSA-201688|reactome:R-HSA-2028269|reactome:R-HSA-4086400|reactome:R-HSA-4608870|reactome:R-HSA-4641258|reactome:R-HSA-4641262|reactome:R-HSA-5099900|reactome:R-HSA-5368598|reactome:R-HSA-5663220|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9673324|ensembl:ENSP00000005340|dip:DIP-34433N	refseq:NP_011334.1|sgd:S000003149|mint:P40956|dip:DIP-2746N|ensemblfungi:YGL181W(gene)|ensemblfungi:YGL181W_mRNA(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0006897"(endocytosis)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010512"(negative regulation of phosphatidylinositol biosynthetic process)|go:"GO:0030479"(actin cortical patch)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR037278|interpro:IPR038508	-	-	crc64:D687E3BF6B620795	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:2Vdc8oRnT4Mz/j+EXQXrL3AszOc9606	rogid:8kgpssCRrHiTHsFaOH2nDK6EIjk559292	intact-crc:86FDEB4A3AF7CE4E|rigid:f+XqEw2aghQg19Q6AH+2v3F0+68	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:A0A0A0MQZ8	uniprotkb:P40956	intact:EBI-11531560|ensembl:ENSP00000297183	intact:EBI-7968|uniprotkb:D6VTX2|ensemblfungi:YGL181W	psi-mi:a0a0a0mqz8_human(display_long)|uniprotkb:ANKHD1(gene name)|psi-mi:ANKHD1(display_short)	psi-mi:gts1_yeast(display_long)|uniprotkb:YGL181W(locus name)|uniprotkb:GTS1(gene name)|psi-mi:GTS1(display_short)|uniprotkb:LSR1(gene name synonym)|uniprotkb:Protein LSR1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549972|imex:IM-24995-3064	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000131503(gene)|ensembl:ENST00000297183(transcript)|go:"GO:0003723"(RNA binding)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR036612	refseq:NP_011334.1|sgd:S000003149|mint:P40956|dip:DIP-2746N|ensemblfungi:YGL181W(gene)|ensemblfungi:YGL181W_mRNA(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0006897"(endocytosis)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010512"(negative regulation of phosphatidylinositol biosynthetic process)|go:"GO:0030479"(actin cortical patch)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR037278|interpro:IPR038508	-	-	crc64:D687E3BF6B620795	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:o5PbZ86LdldDZqy6ao7ukLpABbE9606	rogid:8kgpssCRrHiTHsFaOH2nDK6EIjk559292	intact-crc:443DAC5782638A9F|rigid:/22GAeVY0E/rn992a9sDkg20l8w	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O43251-3	uniprotkb:P40956	intact:EBI-11531589|ensembl:ENSP00000262829|ensembl:ENSP00000485711	intact:EBI-7968|uniprotkb:D6VTX2|ensemblfungi:YGL181W	psi-mi:o43251-3(display_long)|uniprotkb:RBFOX2(gene name)|psi-mi:RBFOX2(display_short)|uniprotkb:FOX2(gene name synonym)|uniprotkb:Fox-1 homolog B(gene name synonym)|uniprotkb:HRNBP2(gene name synonym)|uniprotkb:Hexaribonucleotide-binding protein 2(gene name synonym)|uniprotkb:RBM9(gene name synonym)|uniprotkb:RNA-binding motif protein 9(gene name synonym)|uniprotkb:RNA-binding protein 9(gene name synonym)|uniprotkb:RTA(gene name synonym)|uniprotkb:Repressor of tamoxifen transcriptional activity(gene name synonym)	psi-mi:gts1_yeast(display_long)|uniprotkb:YGL181W(locus name)|uniprotkb:GTS1(gene name)|psi-mi:GTS1(display_short)|uniprotkb:LSR1(gene name synonym)|uniprotkb:Protein LSR1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549968|imex:IM-24995-3063	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-746056(isoform-parent)|ensembl:ENSG00000100320(gene)|ensembl:ENSG00000277564(gene)|ensembl:ENST00000262829(transcript)|ensembl:ENST00000631365(transcript)|uniprotkb:O43251-3(isoform-parent)	refseq:NP_011334.1|sgd:S000003149|mint:P40956|dip:DIP-2746N|ensemblfungi:YGL181W(gene)|ensemblfungi:YGL181W_mRNA(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0006897"(endocytosis)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010512"(negative regulation of phosphatidylinositol biosynthetic process)|go:"GO:0030479"(actin cortical patch)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR037278|interpro:IPR038508	-	isoform-comment:No experimental confirmation available. Contains a omega-N-methylarginine at position 249.	crc64:D687E3BF6B620795	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:NFXIvVJoroP1SezcZfQYKHTlTR09606	rogid:8kgpssCRrHiTHsFaOH2nDK6EIjk559292	intact-crc:C11B163918304252|rigid:D7Jga27uEEhBeK+L+m1yop8Wfsk	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8N5R6	uniprotkb:P40560	intact:EBI-740841|intact:EBI-953781|uniprotkb:B3KQ49|uniprotkb:A8K3U4|uniprotkb:A8MPQ6|uniprotkb:A8MV61|uniprotkb:A8MVU9|uniprotkb:Q9H5Q6|uniprotkb:Q8TAX6|intact:EBI-2320546|intact:EBI-11522976	intact:EBI-24911|uniprotkb:D6VVT0|ensemblfungi:YIL001W	psi-mi:ccd33_human(display_long)|uniprotkb:CCDC33(gene name)|psi-mi:CCDC33(display_short)|uniprotkb:Cancer/testis antigen 61(gene name synonym)	psi-mi:yia1_yeast(display_long)|uniprotkb:YIA1W(orf name)|uniprotkb:YIL001W(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549952|imex:IM-24995-3059	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_079331.3|interpro:IPR000008(C2 calcium-dependent membrane targeting)|go:"GO:0005777"(peroxisome)|refseq:NP_001274110.1|refseq:NP_877592.2|mint:Q8N5R6|interpro:IPR035892|interpro:IPR039889	sgd:S000001263|refseq:NP_012265.3|dip:DIP-1375N|ensemblfungi:YIL001W(gene)|ensemblfungi:YIL001W_mRNA(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0005737"(cytoplasm)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR036770|interpro:IPR044515	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2021/11/30	rogid:eEIn7pQyfdHWx8TeLJpYy0i/gww9606	rogid:IOv6oxjYJ3W/jLnmIcM03RDQ8Ww559292	intact-crc:6121D7D329E90A79|rigid:pxGUZW0PhxoZskEkamFgZBgxPHE	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:A0A6A5PPQ8	uniprotkb:P40855	intact:EBI-11522307	intact:EBI-594747|uniprotkb:Q8NI97|intact:EBI-981972|uniprotkb:Q5QNY4|uniprotkb:D3DVE7|ensembl:ENSP00000357051	psi-mi:a0a6a5ppq8_yeasx(display_long)|uniprotkb:PACBIOSEQ_LOCUS4583(orf name)|uniprotkb:PACBIOSEQ_LOCUS4587(orf name)|uniprotkb:PACBIOSEQ_LOCUS4600(orf name)|uniprotkb:PACBIOSEQ_LOCUS4626(orf name)|uniprotkb:PACBIOSEQ_LOCUS4639(orf name)|uniprotkb:PACBIOSEQ_LOCUS4679(orf name)	psi-mi:pex19_human(display_long)|uniprotkb:PEX19(gene name)|psi-mi:PEX19(display_short)|uniprotkb:HK33(gene name synonym)|uniprotkb:PXF(gene name synonym)|uniprotkb:OK/SW-cl.22(orf name)|uniprotkb:Peroxin-19(gene name synonym)|uniprotkb:Peroxisomal farnesylated protein(gene name synonym)|uniprotkb:33 kDa housekeeping protein(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549960|imex:IM-24995-3061	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016021"(integral component of membrane)|uniprotkb:A0A250WEQ4(uniprot-removed-ac)	refseq:NP_001180573.1|refseq:NP_002848.1|dip:DIP-24172N|ensembl:ENSG00000162735(gene)|ensembl:ENST00000368072(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006625"(protein targeting to peroxisome)|go:"GO:0007031"(peroxisome organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016557"(peroxisome membrane biogenesis)|go:"GO:0016559"(peroxisome fission)|go:"GO:0031526"(brush border membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033328"(peroxisome membrane targeting sequence binding)|go:"GO:0036105"(peroxisome membrane class-1 targeting sequence binding)|go:"GO:0045046"(protein import into peroxisome membrane)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0072663"(establishment of protein localization to peroxisome)|go:"GO:0140597"(protein carrier chaperone)|go:"GO:1900131"(negative regulation of lipid binding)|interpro:IPR006708(Pex19 protein)|interpro:IPR038322|mint:P40855|rcsb pdb:2W85|rcsb pdb:2WL8|rcsb pdb:3AJB|rcsb pdb:3MK4|rcsb pdb:5LNF|reactome:R-HSA-1369062|reactome:R-HSA-9603798	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:f+RZksZwcG8Xqd6IVrksanQ54vE4932	rogid:yNnX2hPPJ7miGaz2Req0qFn0L189606	intact-crc:076ACFCE7C2F1BB6|rigid:ygWK9jcKDtOt4y7w3JAAtKGOTWE	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P40560	uniprotkb:P26641	intact:EBI-24911|uniprotkb:D6VVT0|ensemblfungi:YIL001W	intact:EBI-351467|uniprotkb:Q6PJ62|uniprotkb:Q6PK31|uniprotkb:Q96CU2|uniprotkb:Q9P196|intact:EBI-2321928|uniprotkb:B4DTG2|ensembl:ENSP00000331901	psi-mi:yia1_yeast(display_long)|uniprotkb:YIA1W(orf name)|uniprotkb:YIL001W(locus name)	psi-mi:ef1g_human(display_long)|uniprotkb:PRO1608(orf name)|uniprotkb:EEF1G(gene name)|psi-mi:EEF1G(display_short)|uniprotkb:EF1G(gene name synonym)|uniprotkb:eEF-1B gamma(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549956|imex:IM-24995-3060	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000001263|refseq:NP_012265.3|dip:DIP-1375N|ensemblfungi:YIL001W(gene)|ensemblfungi:YIL001W_mRNA(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0005737"(cytoplasm)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR036770|interpro:IPR044515	refseq:NP_001395.1|ensembl:ENSG00000254772(gene)|ensembl:ENST00000329251(transcript)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006414"(translational elongation)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001662(Translation elongation factor EF1B, gamma chain, conserved)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR036249|interpro:IPR036282|interpro:IPR036433|interpro:IPR040079|mint:P26641|rcsb pdb:1PBU|rcsb pdb:5DQS|rcsb pdb:5JPO|reactome:R-HSA-156842|dip:DIP-32516N	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:IOv6oxjYJ3W/jLnmIcM03RDQ8Ww559292	rogid:biVN96umeEdPm/wvPN4VwbSRHTs9606	intact-crc:70937A774E1293FA|rigid:5DcFCkb5tofX9knZyCskKKL7DSI	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P40956	uniprotkb:P23511-2	intact:EBI-7968|uniprotkb:D6VTX2|ensemblfungi:YGL181W	intact:EBI-11061759|ensembl:ENSP00000229418	psi-mi:gts1_yeast(display_long)|uniprotkb:YGL181W(locus name)|uniprotkb:GTS1(gene name)|psi-mi:GTS1(display_short)|uniprotkb:LSR1(gene name synonym)|uniprotkb:Protein LSR1(gene name synonym)	psi-mi:p23511-2(display_long)|uniprotkb:NFYA(gene name)|psi-mi:NFYA(display_short)|uniprotkb:CAAT box DNA-binding protein subunit A(gene name synonym)|uniprotkb:Nuclear transcription factor Y subunit A(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549964|imex:IM-24995-3062	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011334.1|sgd:S000003149|mint:P40956|dip:DIP-2746N|ensemblfungi:YGL181W(gene)|ensemblfungi:YGL181W_mRNA(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0006897"(endocytosis)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010512"(negative regulation of phosphatidylinositol biosynthetic process)|go:"GO:0030479"(actin cortical patch)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR037278|interpro:IPR038508	intact:EBI-389739(isoform-parent)|ensembl:ENSG00000001167(gene)|ensembl:ENST00000353205(transcript)|uniprotkb:P23511-2(isoform-parent)	-	crc64:D687E3BF6B620795	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:8kgpssCRrHiTHsFaOH2nDK6EIjk559292	rogid:9IOUoaGszX6kd9hzrCj6BBkgJ+09606	intact-crc:57780F52330F516E|rigid:71UqtccFw4nTapWPLP3j01Da15k	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P40956	uniprotkb:O43186	intact:EBI-7968|uniprotkb:D6VTX2|ensemblfungi:YGL181W	intact:EBI-748171|uniprotkb:Q0QD45|ensembl:ENSP00000221996|ensembl:ENSP00000445565	psi-mi:gts1_yeast(display_long)|uniprotkb:YGL181W(locus name)|uniprotkb:GTS1(gene name)|psi-mi:GTS1(display_short)|uniprotkb:LSR1(gene name synonym)|uniprotkb:Protein LSR1(gene name synonym)	psi-mi:crx_human(display_long)|uniprotkb:CRX(gene name)|psi-mi:CRX(display_short)|uniprotkb:CORD2(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549980|imex:IM-24995-3066	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011334.1|sgd:S000003149|mint:P40956|dip:DIP-2746N|ensemblfungi:YGL181W(gene)|ensemblfungi:YGL181W_mRNA(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0006897"(endocytosis)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010512"(negative regulation of phosphatidylinositol biosynthetic process)|go:"GO:0030479"(actin cortical patch)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR037278|interpro:IPR038508	refseq:NP_000545.1|ensembl:ENSG00000105392(gene)|ensembl:ENST00000221996(transcript)|ensembl:ENST00000539067(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007601"(visual perception)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050896"(response to stimulus)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013851(Transcription factor Otx, C-terminal)|interpro:IPR017970	-	crc64:D687E3BF6B620795	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:8kgpssCRrHiTHsFaOH2nDK6EIjk559292	rogid:v/bkO/0iLzq1Q2HtieWQQ40RF9M9606	intact-crc:A6E695FD982F3A13|rigid:G2P8FEYVyuPKDDMlW1xHCR97OT8	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P43355	uniprotkb:P28004	intact:EBI-740978|ensembl:ENSP00000349085|uniprotkb:O00346|uniprotkb:B2RC81	intact:EBI-20640|uniprotkb:D6VPI6|ensemblfungi:YAL032C	psi-mi:maga1_human(display_long)|uniprotkb:MAGE-1 antigen(gene name synonym)|uniprotkb:Antigen MZ2-E(gene name synonym)|uniprotkb:Cancer/testis antigen 1.1(gene name synonym)|uniprotkb:MAGEA1(gene name)|psi-mi:MAGEA1(display_short)|uniprotkb:MAGE1(gene name synonym)|uniprotkb:MAGE1A(gene name synonym)	psi-mi:prp45_yeast(display_long)|uniprotkb:YAL032C(locus name)|uniprotkb:PRP45(gene name)|psi-mi:PRP45(display_short)|uniprotkb:FUN20(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550008|imex:IM-24995-3073	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004979.3|ensembl:ENSG00000198681(gene)|ensembl:ENST00000356661(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|interpro:IPR002190(MAGE protein)|interpro:IPR021072|interpro:IPR030093|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|rcsb pdb:1W72|rcsb pdb:3BO8|dip:DIP-54794N	refseq:NP_009370.1|sgd:S000000030|ensemblfungi:YAL032C(gene)|ensemblfungi:YAL032C_mRNA(transcript)|go:"GO:0000350"(generation of catalytic spliceosome for second transesterification step)|go:"GO:0005634"(nucleus)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|interpro:IPR004015(SKIP/SNW)|interpro:IPR017862|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|dip:DIP-2774N|mint:P28004	-	crc64:544EEB1F9F4E9D33	crc64:FE5A724186D7FE84	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:6XW3mnTNM3yvOtXmiFbU8Uz3hjA9606	rogid:qoHF1UsO3k+JOTOfigSuy2P84/k559292	intact-crc:7B50EE401F01D704|rigid:atlGVCsRYtMXruwX/AYXgfjHlJs	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P43355	uniprotkb:P00431	intact:EBI-740978|ensembl:ENSP00000349085|uniprotkb:O00346|uniprotkb:B2RC81	intact:EBI-4389|uniprotkb:Q6Q5M9|uniprotkb:D6VXC7|ensemblfungi:YKR066C	psi-mi:maga1_human(display_long)|uniprotkb:MAGE-1 antigen(gene name synonym)|uniprotkb:Antigen MZ2-E(gene name synonym)|uniprotkb:Cancer/testis antigen 1.1(gene name synonym)|uniprotkb:MAGEA1(gene name)|psi-mi:MAGEA1(display_short)|uniprotkb:MAGE1(gene name synonym)|uniprotkb:MAGE1A(gene name synonym)	psi-mi:ccpr_yeast(display_long)|uniprotkb:CCP1(gene name)|psi-mi:CCP1(display_short)|uniprotkb:CCP(gene name synonym)|uniprotkb:CPO(gene name synonym)|uniprotkb:YKR066C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550004|imex:IM-24995-3072	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004979.3|ensembl:ENSG00000198681(gene)|ensembl:ENST00000356661(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|interpro:IPR002190(MAGE protein)|interpro:IPR021072|interpro:IPR030093|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|rcsb pdb:1W72|rcsb pdb:3BO8|dip:DIP-54794N	refseq:NP_012992.1|sgd:S000001774|dip:DIP-6251N|ensemblfungi:YKR066C(gene)|ensemblfungi:YKR066C_mRNA(transcript)|go:"GO:0000302"(response to reactive oxygen species)|go:"GO:0004130"(cytochrome-c peroxidase activity)|go:"GO:0004601"(peroxidase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0020037"(heme binding)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0046872"(metal ion binding)|interpro:IPR002016(Haem peroxidase, plant/fungal/bacterial)|interpro:IPR002207(Plant ascorbate peroxidase)|interpro:IPR010255(Haem peroxidase)|interpro:IPR019793|interpro:IPR019794|interpro:IPR044831|rcsb pdb:1A2F|rcsb pdb:1A2G|rcsb pdb:1AA4|rcsb pdb:1AC4|rcsb pdb:1AC8|rcsb pdb:1AEB|rcsb pdb:1AED|rcsb pdb:1AEE|rcsb pdb:1AEF|rcsb pdb:1AEG|rcsb pdb:1AEH|rcsb pdb:1AEJ|rcsb pdb:1AEK|rcsb pdb:1AEM|rcsb pdb:1AEN|rcsb pdb:1AEO|rcsb pdb:1AEQ|rcsb pdb:1AES|rcsb pdb:1AET|rcsb pdb:1AEU|rcsb pdb:1AEV|rcsb pdb:1BEJ|rcsb pdb:1BEK|rcsb pdb:1BEM|rcsb pdb:1BEP|rcsb pdb:1BEQ|rcsb pdb:1BES|rcsb pdb:1BJ9|rcsb pdb:1BVA|rcsb pdb:1CCA|rcsb pdb:1CCB|rcsb pdb:1CCC|rcsb pdb:1CCE|rcsb pdb:1CCG|rcsb pdb:1CCI|rcsb pdb:1CCJ|rcsb pdb:1CCK|rcsb pdb:1CCL|rcsb pdb:1CCP|rcsb pdb:1CMP|rcsb pdb:1CMQ|rcsb pdb:1CMT|rcsb pdb:1CPD|rcsb pdb:1CPE|rcsb pdb:1CPF|rcsb pdb:1CPG|rcsb pdb:1CYF|rcsb pdb:1DCC|rcsb pdb:1DJ1|rcsb pdb:1DJ5|rcsb pdb:1DS4|rcsb pdb:1DSE|rcsb pdb:1DSG|rcsb pdb:1DSO|rcsb pdb:1DSP|rcsb pdb:1EBE|rcsb pdb:1JCI|rcsb pdb:1JDR|rcsb pdb:1KOK|rcsb pdb:1KRJ|rcsb pdb:1KXM|rcsb pdb:1KXN|rcsb pdb:1MK8|rcsb pdb:1MKQ|rcsb pdb:1MKR|rcsb pdb:1ML2|rcsb pdb:1RYC|rcsb pdb:1S6V|rcsb pdb:1S73|rcsb pdb:1SBM|rcsb pdb:1SDQ|rcsb pdb:1SOG|rcsb pdb:1STQ|rcsb pdb:1U74|rcsb pdb:1U75|rcsb pdb:1Z53|rcsb pdb:1ZBY|rcsb pdb:1ZBZ|rcsb pdb:2ANZ|rcsb pdb:2AQD|rcsb pdb:2AS1|rcsb pdb:2AS2|rcsb pdb:2AS3|rcsb pdb:2AS4|rcsb pdb:2AS6|rcsb pdb:2B0Z|rcsb pdb:2B10|rcsb pdb:2B11|rcsb pdb:2B12|rcsb pdb:2BCN|rcsb pdb:2CCP|rcsb pdb:2CEP|rcsb pdb:2CYP|rcsb pdb:2EUN|rcsb pdb:2EUO|rcsb pdb:2EUP|rcsb pdb:2EUQ|rcsb pdb:2EUR|rcsb pdb:2EUS|rcsb pdb:2EUT|rcsb pdb:2EUU|rcsb pdb:2GB8|rcsb pdb:2IA8|rcsb pdb:2ICV|rcsb pdb:2JTI|rcsb pdb:2N18|rcsb pdb:2PCB|rcsb pdb:2PCC|rcsb pdb:2RBT|rcsb pdb:2RBU|rcsb pdb:2RBV|rcsb pdb:2RBW|rcsb pdb:2RBX|rcsb pdb:2RBY|rcsb pdb:2RBZ|rcsb pdb:2RC0|rcsb pdb:2RC1|rcsb pdb:2RC2|rcsb pdb:2V23|rcsb pdb:2V2E|rcsb pdb:2X07|rcsb pdb:2X08|rcsb pdb:2XIL|rcsb pdb:2XJ5|rcsb pdb:2XJ8|rcsb pdb:2Y5A|rcsb pdb:2YCG|rcsb pdb:3CCP|rcsb pdb:3CCX|rcsb pdb:3E2N|rcsb pdb:3E2O|rcsb pdb:3EXB|rcsb pdb:3M23|rcsb pdb:3M25|rcsb pdb:3M26|rcsb pdb:3M27|rcsb pdb:3M28|rcsb pdb:3M29|rcsb pdb:3M2A|rcsb pdb:1CMU|rcsb pdb:3M2B|rcsb pdb:3M2C|rcsb pdb:3M2D|rcsb pdb:3M2E|rcsb pdb:3M2F|rcsb pdb:3M2G|rcsb pdb:3M2H|rcsb pdb:3M2I|rcsb pdb:3R98|rcsb pdb:3R99|rcsb pdb:4A6Z|rcsb pdb:4A71|rcsb pdb:4A78|rcsb pdb:4A7M|rcsb pdb:4CCP|rcsb pdb:4CCX|rcsb pdb:4CVI|rcsb pdb:4CVJ|rcsb pdb:4JB4|rcsb pdb:4NFG|rcsb pdb:4P4Q|rcsb pdb:4XV4|rcsb pdb:4XV5|rcsb pdb:4XV6|rcsb pdb:4XV7|rcsb pdb:4XV8|rcsb pdb:4XVA|rcsb pdb:5CCP|rcsb pdb:5CIB|rcsb pdb:5CIC|rcsb pdb:5CID|rcsb pdb:5CIE|rcsb pdb:5CIF|rcsb pdb:5CIG|rcsb pdb:5CIH|rcsb pdb:5D6M|rcsb pdb:5EJT|rcsb pdb:5EJX|rcsb pdb:6CCP|rcsb pdb:6H08|rcsb pdb:6P41|rcsb pdb:6P42|rcsb pdb:6P43|rcsb pdb:6Y1T|rcsb pdb:6Y2Y|rcsb pdb:7CCP	-	crc64:544EEB1F9F4E9D33	crc64:A5D26385DA6F0A0B	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:6XW3mnTNM3yvOtXmiFbU8Uz3hjA9606	rogid:LkPXY1wuYoCFzMQPSsAtXZrRi8w559292	intact-crc:6F4DCAA872D8D55A|rigid:VQneuJ3S6d1jG8dpkHfjjzGW/0w	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O43791	uniprotkb:P40959	intact:EBI-743549|uniprotkb:Q53HJ1|uniprotkb:B2R6S3|uniprotkb:D3DTW7|ensembl:ENSP00000240327|ensembl:ENSP00000377001|ensembl:ENSP00000420908|ensembl:ENSP00000424119|ensembl:ENSP00000425905|ensembl:ENSP00000426986|ensembl:ENSP00000499562	intact:EBI-11636|ensemblfungi:YMR004W|uniprotkb:D6VZH9	psi-mi:spop_human(display_long)|uniprotkb:HIB homolog 1(gene name synonym)|uniprotkb:Roadkill homolog 1(gene name synonym)|uniprotkb:SPOP(gene name)|psi-mi:SPOP(display_short)	psi-mi:mvp1_yeast(display_long)|uniprotkb:MVP1(gene name)|psi-mi:MVP1(display_short)|uniprotkb:YM8270.06(orf name)|uniprotkb:YMR004W(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549984|imex:IM-24995-3067	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001007227.1|refseq:NP_001007228.1|refseq:NP_001007229.1|refseq:NP_001007230.1|refseq:NP_001007231.1|refseq:NP_003554.1|refseq:XP_005257780.1|refseq:XP_005257781.1|ensembl:ENSG00000121067(gene)|ensembl:ENST00000347630(transcript)|ensembl:ENST00000393328(transcript)|ensembl:ENST00000503676(transcript)|ensembl:ENST00000504102(transcript)|ensembl:ENST00000509079(transcript)|ensembl:ENST00000514121(transcript)|ensembl:ENST00000665825(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0016607"(nuclear speck)|go:"GO:0030162"(regulation of proteolysis)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR034089|mint:O43791|rcsb pdb:2CR2|rcsb pdb:3HQH|rcsb pdb:3HQI|rcsb pdb:3HQL|rcsb pdb:3HQM|rcsb pdb:3HSV|rcsb pdb:3HTM|rcsb pdb:3HU6|rcsb pdb:3IVB|rcsb pdb:3IVQ|rcsb pdb:3IVV|rcsb pdb:4EOZ|rcsb pdb:4HS2|rcsb pdb:4J8Z|rcsb pdb:4O1V|rcsb pdb:6F8F|rcsb pdb:6F8G|rcsb pdb:6I41|rcsb pdb:6I5P|rcsb pdb:6I68|rcsb pdb:6I7A|rcsb pdb:7D3D|rcsb pdb:7LIN|rcsb pdb:7LIO|rcsb pdb:7LIP|rcsb pdb:7LIQ|reactome:R-HSA-5632684|go:"GO:0005634"(nucleus)|refseq:XP_016880693.1|dip:DIP-50517N	ensemblfungi:YMR004W(gene)|ensemblfungi:YMR004W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0016020"(membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0097320"(plasma membrane tubulation)|interpro:IPR001683(Phox-like)|interpro:IPR028662|interpro:IPR035704|interpro:IPR036871|rcsb pdb:6Q0X|refseq:NP_013717.1|sgd:S000004606|mint:P40959|dip:DIP-1764N	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:PC9ofpvk14xwTnnqT590/YRnx/49606	rogid:3IrMPCYXP5yb2l52Uhu2DiEuNdI559292	intact-crc:B7F78D14B02A6753|rigid:W0IEqqkqzN/r9Rp/S5G9rR8DnFc	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q08379	uniprotkb:P42944	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	intact:EBI-8042|uniprotkb:D6VW74|ensemblfungi:YJL110C	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:gzf3_yeast(display_long)|uniprotkb:GZF3(gene name)|psi-mi:GZF3(display_short)|uniprotkb:J0806(orf name)|uniprotkb:YJL110C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549996|imex:IM-24995-3070	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N	refseq:NP_012425.1|sgd:S000003646|mint:P42944|dip:DIP-1359N|ensemblfungi:YJL110C(gene)|ensemblfungi:YJL110C_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0090295"(nitrogen catabolite repression of transcription)|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR039355|reactome:R-SCE-9018519	-	-	crc64:807243799BFAB704	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2017/05/26	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	rogid:HOMBFcxVuABRuzPHcnDG87+R6sQ559292	intact-crc:77BBA0429C8DE0CD|rigid:6LN/DmegS/tGLsg5/MUSFS6ztsk	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P42937	uniprotkb:Q8N5R6	intact:EBI-23470|uniprotkb:D6VUY5|ensemblfungi:YGR203W	intact:EBI-740841|intact:EBI-953781|uniprotkb:B3KQ49|uniprotkb:A8K3U4|uniprotkb:A8MPQ6|uniprotkb:A8MV61|uniprotkb:A8MVU9|uniprotkb:Q9H5Q6|uniprotkb:Q8TAX6|intact:EBI-2320546|intact:EBI-11522976	psi-mi:ych1_yeast(display_long)|uniprotkb:YGR203W(locus name)|uniprotkb:G7731(orf name)|uniprotkb:YCH1(gene name)|psi-mi:YCH1(display_short)|uniprotkb:CDC25 homolog 1(gene name synonym)	psi-mi:ccd33_human(display_long)|uniprotkb:CCDC33(gene name)|psi-mi:CCDC33(display_short)|uniprotkb:Cancer/testis antigen 61(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549992|imex:IM-24995-3069	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011719.1|sgd:S000003435|dip:DIP-885N|ensemblfungi:YGR203W(gene)|ensemblfungi:YGR203W_mRNA(transcript)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0004792"(thiosulfate sulfurtransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016311"(dephosphorylation)|go:"GO:0016791"(phosphatase activity)|interpro:IPR001763(Rhodanese-like)|interpro:IPR036873|rcsb pdb:3F4A|rcsb pdb:3FS5	refseq:NP_079331.3|interpro:IPR000008(C2 calcium-dependent membrane targeting)|go:"GO:0005777"(peroxisome)|refseq:NP_001274110.1|refseq:NP_877592.2|mint:Q8N5R6|interpro:IPR035892|interpro:IPR039889	-	crc64:41527DB282CBFF11	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2021/11/30	rogid:p8SYf/V7HMF1NdntyAYkfOBvlPk559292	rogid:eEIn7pQyfdHWx8TeLJpYy0i/gww9606	intact-crc:3F016861DA2C9D30|rigid:+vXoUJGEq5t7Gf9Xfd8nxl0T6uM	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P42843	uniprotkb:P40692	intact:EBI-28370|uniprotkb:Q6B2L9|uniprotkb:D6W0N4|ensemblfungi:YNL311C	intact:EBI-744248|uniprotkb:B4DI13|uniprotkb:B4DQ11|uniprotkb:E9PCU2|ensembl:ENSP00000231790	psi-mi:skp2_yeast(display_long)|uniprotkb:N0376(orf name)|uniprotkb:YNL311C(locus name)|uniprotkb:SKP2(gene name)|psi-mi:SKP2(display_short)	psi-mi:mlh1_human(display_long)|uniprotkb:MutL protein homolog 1(gene name synonym)|uniprotkb:MLH1(gene name)|psi-mi:MLH1(display_short)|uniprotkb:COCA2(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11549988|imex:IM-24995-3068	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014088.1|sgd:S000005255|dip:DIP-1971N|ensemblfungi:YNL311C(gene)|ensemblfungi:YNL311C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031335"(regulation of sulfur amino acid metabolic process)|go:"GO:0044257"(cellular protein catabolic process)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR036047	refseq:NP_000240.1|refseq:NP_001161089.1|refseq:NP_001161090.1|refseq:NP_001161091.1|refseq:NP_001245200.1|refseq:NP_001245202.1|refseq:NP_001245203.1|dip:DIP-27601N|refseq:XP_005265220.1|refseq:XP_005265221.1|ensembl:ENSG00000076242(gene)|ensembl:ENST00000231790(transcript)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005712"(chiasma)|go:"GO:0005715"(late recombination nodule)|go:"GO:0006298"(mismatch repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0007060"(male meiosis chromosome segregation)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0009617"(response to bacterium)|go:"GO:0016020"(membrane)|go:"GO:0016321"(female meiosis chromosome segregation)|go:"GO:0016446"(somatic hypermutation of immunoglobulin genes)|go:"GO:0019899"(enzyme binding)|go:"GO:0032137"(guanine/thymine mispair binding)|go:"GO:0032300"(mismatch repair complex)|go:"GO:0032389"(MutLalpha complex)|go:"GO:0043060"(meiotic metaphase I plate congression)|go:"GO:0045141"(meiotic telomere clustering)|go:"GO:0045190"(isotype switching)|go:"GO:0045950"(negative regulation of mitotic recombination)|go:"GO:0048298"(positive regulation of isotype switching to IgA isotypes)|go:"GO:0048304"(positive regulation of isotype switching to IgG isotypes)|go:"GO:0048477"(oogenesis)|go:"GO:0051257"(meiotic spindle midzone assembly)|interpro:IPR002099(DNA mismatch repair protein)|interpro:IPR013507(DNA mismatch repair protein, C-terminal)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR014762(DNA mismatch repair, conserved site)|interpro:IPR020568|interpro:IPR032189|interpro:IPR036890|interpro:IPR038973|mint:P40692|rcsb pdb:3RBN|rcsb pdb:4P7A|rcsb pdb:5U5P|reactome:R-HSA-5358565|reactome:R-HSA-5358606|reactome:R-HSA-5545483|reactome:R-HSA-5632987|reactome:R-HSA-6796648|reactome:R-HSA-912446	-	crc64:81102168449051BC	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:cvjKu9olqbvbZPvhBL6DK754CVA559292	rogid:v/ydpM1Cf5bF27dC+3JF6XXMp0Q9606	intact-crc:BDD07452161167C9|rigid:kYwRq4BtBtFhSAL5N1qqzkJjwfs	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P17255	uniprotkb:P43355	intact:EBI-20245|uniprotkb:O74301|uniprotkb:Q9Y7W5|uniprotkb:D6VRG7|ensemblfungi:YDL185W	intact:EBI-740978|ensembl:ENSP00000349085|uniprotkb:O00346|uniprotkb:B2RC81	psi-mi:vata_yeast(display_long)|uniprotkb:VMA1(gene name)|psi-mi:VMA1(display_short)|uniprotkb:CLS8(gene name synonym)|uniprotkb:TFP1(gene name synonym)|uniprotkb:YDL185W(locus name)|uniprotkb:D1286(orf name)|uniprotkb:Vacuolar proton pump subunit A(gene name synonym)	psi-mi:maga1_human(display_long)|uniprotkb:MAGE-1 antigen(gene name synonym)|uniprotkb:Antigen MZ2-E(gene name synonym)|uniprotkb:Cancer/testis antigen 1.1(gene name synonym)|uniprotkb:MAGEA1(gene name)|psi-mi:MAGEA1(display_short)|uniprotkb:MAGE1(gene name synonym)|uniprotkb:MAGE1A(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550000|imex:IM-24995-3071	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010096.1|sgd:S000002344|mint:P17255|ensemblfungi:YDL185W(gene)|ensemblfungi:YDL185W_mRNA(transcript)|go:"GO:0000221"(vacuolar proton-transporting V-type ATPase, V1 domain)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0003677"(DNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006314"(intron homing)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0012505"(endomembrane system)|go:"GO:0016539"(intein-mediated protein splicing)|go:"GO:0044267"(cellular protein metabolic process)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR003586(Hedgehog/intein hint domain, C-terminal)|interpro:IPR003587(Hedgehog/intein hint, N-terminal)|interpro:IPR004042(Intein DOD homing endonuclease)|interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR006141(Intein splicing site)|interpro:IPR006142(Intein)|interpro:IPR007868(Hom-end-associated Hint)|interpro:IPR007869(Homing endonuclease)|interpro:IPR020003|interpro:IPR022878|interpro:IPR023366|interpro:IPR027417|interpro:IPR027434|interpro:IPR030934|interpro:IPR031686|interpro:IPR036121|interpro:IPR036844|rcsb pdb:1DFA|rcsb pdb:1EF0|rcsb pdb:1GPP|rcsb pdb:1JVA|rcsb pdb:1LWS|rcsb pdb:1LWT|rcsb pdb:1UM2|rcsb pdb:1VDE|rcsb pdb:3J9T|rcsb pdb:3J9U|rcsb pdb:3J9V|rcsb pdb:5BW9|rcsb pdb:5D80|rcsb pdb:5VOX|rcsb pdb:5VOY|rcsb pdb:5VOZ|reactome:R-SCE-1222556|reactome:R-SCE-77387|reactome:R-SCE-917977|reactome:R-SCE-9639288|interpro:IPR024034|dip:DIP-2293N	refseq:NP_004979.3|ensembl:ENSG00000198681(gene)|ensembl:ENST00000356661(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|interpro:IPR002190(MAGE protein)|interpro:IPR021072|interpro:IPR030093|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|rcsb pdb:1W72|rcsb pdb:3BO8|dip:DIP-54794N	-	crc64:2A4C65D2F59426FD	crc64:544EEB1F9F4E9D33	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:YdmGZxIMX2IXMHC4EO85uOAf1Hg559292	rogid:6XW3mnTNM3yvOtXmiFbU8Uz3hjA9606	intact-crc:50174B4156D49198|rigid:eU2IYpxCFkXgEheF4T+xo6dsyI0	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P38302	uniprotkb:P43365	intact:EBI-20921|uniprotkb:D6VQI3|ensemblfungi:YBR188C	intact:EBI-749530|uniprotkb:Q9NSD3|intact:EBI-10178394|uniprotkb:Q6FHH8|ensembl:ENSP00000350592|ensembl:ENSP00000377447|ensembl:ENSP00000377478	psi-mi:ntc20_yeast(display_long)|uniprotkb:YBR188C(locus name)|uniprotkb:YBR1316(orf name)|uniprotkb:NTC20(gene name)|psi-mi:NTC20(display_short)|uniprotkb:SNT384(gene name synonym)|uniprotkb:PRP19-associated complex protein 20(gene name synonym)|uniprotkb:Synergistic to PRP19 mutation protein 384(gene name synonym)	psi-mi:magac_human(display_long)|uniprotkb:MAGE-12 antigen(gene name synonym)|uniprotkb:MAGE12F antigen(gene name synonym)|uniprotkb:Cancer/testis antigen 1.12(gene name synonym)|uniprotkb:MAGEA12(gene name)|psi-mi:MAGEA12(display_short)|uniprotkb:MAGE12(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550044|imex:IM-24995-3082	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009747.3|sgd:S000000392|mint:P38302|ensemblfungi:YBR188C(gene)|ensemblfungi:YBR188C_mRNA(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000974"(Prp19 complex)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|dip:DIP-1683N	refseq:NP_001159858.1|refseq:NP_001159859.1|refseq:NP_005358.2|ensembl:ENSG00000213401(gene)|ensembl:ENST00000357916(transcript)|ensembl:ENST00000393869(transcript)|ensembl:ENST00000393900(transcript)|interpro:IPR002190(MAGE protein)|interpro:IPR021072|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899	-	crc64:15C5234B25213223	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:Ucc4R0lhhhAQfrsXvs+BtCnuJQg559292	rogid:3/Jxz2VsFOb67RWqWj3xbTrw3s49606	intact-crc:A4DB9693E33209CA|rigid:vsfcggVYFPxIV6OVMPdpHABFr28	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P43365	uniprotkb:P32502	intact:EBI-749530|uniprotkb:Q9NSD3|intact:EBI-10178394|uniprotkb:Q6FHH8|ensembl:ENSP00000350592|ensembl:ENSP00000377447|ensembl:ENSP00000377478	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:magac_human(display_long)|uniprotkb:MAGE-12 antigen(gene name synonym)|uniprotkb:MAGE12F antigen(gene name synonym)|uniprotkb:Cancer/testis antigen 1.12(gene name synonym)|uniprotkb:MAGEA12(gene name)|psi-mi:MAGEA12(display_short)|uniprotkb:MAGE12(gene name synonym)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550040|imex:IM-24995-3081	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001159858.1|refseq:NP_001159859.1|refseq:NP_005358.2|ensembl:ENSG00000213401(gene)|ensembl:ENST00000357916(transcript)|ensembl:ENST00000393869(transcript)|ensembl:ENST00000393900(transcript)|interpro:IPR002190(MAGE protein)|interpro:IPR021072|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731	-	-	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:3/Jxz2VsFOb67RWqWj3xbTrw3s49606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:8D5E4E73A87F9E07|rigid:6eAeGA0x7ECNoUuCK2qW0T7OZ8Y	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P43365	uniprotkb:O13539	intact:EBI-749530|uniprotkb:Q9NSD3|intact:EBI-10178394|uniprotkb:Q6FHH8|ensembl:ENSP00000350592|ensembl:ENSP00000377447|ensembl:ENSP00000377478	intact:EBI-30898|uniprotkb:D3DLB6|ensemblfungi:YHR167W	psi-mi:magac_human(display_long)|uniprotkb:MAGE-12 antigen(gene name synonym)|uniprotkb:MAGE12F antigen(gene name synonym)|uniprotkb:Cancer/testis antigen 1.12(gene name synonym)|uniprotkb:MAGEA12(gene name)|psi-mi:MAGEA12(display_short)|uniprotkb:MAGE12(gene name synonym)	psi-mi:thp2_yeast(display_long)|uniprotkb:THP2(gene name)|psi-mi:THP2(display_short)|uniprotkb:YHR167W(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550036|imex:IM-24995-3080	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001159858.1|refseq:NP_001159859.1|refseq:NP_005358.2|ensembl:ENSG00000213401(gene)|ensembl:ENST00000357916(transcript)|ensembl:ENST00000393869(transcript)|ensembl:ENST00000393900(transcript)|interpro:IPR002190(MAGE protein)|interpro:IPR021072|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899	refseq:NP_012037.1|sgd:S000001210|dip:DIP-4246N|mint:O13539|ensemblfungi:YHR167W(gene)|ensemblfungi:YHR167W_mRNA(transcript)|go:"GO:0000445"(THO complex part of transcription export complex)|go:"GO:0000446"(nucleoplasmic THO complex)|go:"GO:0000723"(telomere maintenance)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0006310"(DNA recombination)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0034063"(stress granule assembly)|interpro:IPR018557|rcsb pdb:7APX|rcsb pdb:7LUV	-	-	crc64:16EFA6F464507C57	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:3/Jxz2VsFOb67RWqWj3xbTrw3s49606	rogid:SaTSL6jLwX1hTVCqvU8ZNR96r8U559292	intact-crc:03D78F4F09DC5227|rigid:Jen9lZoSJESpiOwO7zbT6YrU1sw	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P25377	uniprotkb:P43365	intact:EBI-2347652|uniprotkb:D6VRA5|ensemblfungi:YCR105W	intact:EBI-749530|uniprotkb:Q9NSD3|intact:EBI-10178394|uniprotkb:Q6FHH8|ensembl:ENSP00000350592|ensembl:ENSP00000377447|ensembl:ENSP00000377478	psi-mi:adh7_yeast(display_long)|uniprotkb:ADH7(gene name)|psi-mi:ADH7(display_short)|uniprotkb:NADP-dependent alcohol dehydrogenase VII(gene name synonym)|uniprotkb:YCR105W(locus name)	psi-mi:magac_human(display_long)|uniprotkb:MAGE-12 antigen(gene name synonym)|uniprotkb:MAGE12F antigen(gene name synonym)|uniprotkb:Cancer/testis antigen 1.12(gene name synonym)|uniprotkb:MAGEA12(gene name)|psi-mi:MAGEA12(display_short)|uniprotkb:MAGE12(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550032|imex:IM-24995-3079	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010030.1|sgd:S000000702|dip:DIP-7661N|mint:P25377|ensemblfungi:YCR105W(gene)|ensemblfungi:YCR105W_mRNA(transcript)|go:"GO:0006066"(alcohol metabolic process)|go:"GO:0008106"("alcohol dehydrogenase (NADP+) activity")|go:"GO:0008270"(zinc ion binding)|go:"GO:0016616"(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|interpro:IPR002328(Alcohol dehydrogenase, zinc-containing, conserved site)|interpro:IPR011032(GroES-like)|interpro:IPR013149(Alcohol dehydrogenase, zinc-binding)|interpro:IPR013154(Alcohol dehydrogenase GroES-like)|interpro:IPR020843|interpro:IPR029752|interpro:IPR036291	refseq:NP_001159858.1|refseq:NP_001159859.1|refseq:NP_005358.2|ensembl:ENSG00000213401(gene)|ensembl:ENST00000357916(transcript)|ensembl:ENST00000393869(transcript)|ensembl:ENST00000393900(transcript)|interpro:IPR002190(MAGE protein)|interpro:IPR021072|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899	-	crc64:BFB0E6C5F93D3F07	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:PGCt+bqhn63vUVgS5IKrrOukXgg559292	rogid:3/Jxz2VsFOb67RWqWj3xbTrw3s49606	intact-crc:B4847B8DFB0F2ECA|rigid:keh5VjBC/XE8jCKzGiHnaFBh6e4	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P43355	intact:EBI-11522208	intact:EBI-740978|ensembl:ENSP00000349085|uniprotkb:O00346|uniprotkb:B2RC81	-	psi-mi:maga1_human(display_long)|uniprotkb:MAGE-1 antigen(gene name synonym)|uniprotkb:Antigen MZ2-E(gene name synonym)|uniprotkb:Cancer/testis antigen 1.1(gene name synonym)|uniprotkb:MAGEA1(gene name)|psi-mi:MAGEA1(display_short)|uniprotkb:MAGE1(gene name synonym)|uniprotkb:MAGE1A(gene name synonym)	psi-mi:ylr445w(display_short)|psi-mi:EBI-11522208(display_long)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550012|imex:IM-24995-3074	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004979.3|ensembl:ENSG00000198681(gene)|ensembl:ENST00000356661(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|interpro:IPR002190(MAGE protein)|interpro:IPR021072|interpro:IPR030093|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|rcsb pdb:1W72|rcsb pdb:3BO8|dip:DIP-54794N	-	-	crc64:544EEB1F9F4E9D33	no-uniprot-update:	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:6XW3mnTNM3yvOtXmiFbU8Uz3hjA9606	rogid:kUe7etYjGLH6i6KZ5N2LXUnjAf04932	intact-crc:D6302AE8CD9D6373|rigid:OyU+sBbEyvPELhKOadGOyFu9W4g	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P32902	uniprotkb:P43361	intact:EBI-16248|ensemblfungi:YHL004W|uniprotkb:D3DKR0	intact:EBI-10182930|uniprotkb:Q9BUN9|intact:EBI-28989087|ensembl:ENSP00000286482|ensembl:ENSP00000438293|ensembl:ENSP00000443776	psi-mi:rt04_yeast(display_long)|uniprotkb:MRP4(gene name)|psi-mi:MRP4(display_short)|uniprotkb:MRP4A(gene name synonym)|uniprotkb:Mitochondrial small ribosomal subunit protein uS2m(gene name synonym)|uniprotkb:YHL004W(locus name)	psi-mi:maga8_human(display_long)|uniprotkb:MAGEA8(gene name)|psi-mi:MAGEA8(display_short)|uniprotkb:Cancer/testis antigen 1.8(gene name synonym)|uniprotkb:MAGE-8 antigen(gene name synonym)|uniprotkb:MAGE8(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550024|imex:IM-24995-3077	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YHL004W(gene)|ensemblfungi:YHL004W_mRNA(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR001865(Ribosomal protein S2)|interpro:IPR005706(Ribosomal protein S2, bacterial-type)|interpro:IPR018130|interpro:IPR023591|rcsb pdb:5MRC|rcsb pdb:5MRE|rcsb pdb:5MRF|refseq:NP_011859.1|sgd:S000000996|dip:DIP-5035N|mint:P32902	refseq:NP_001159872.1|refseq:NP_001159873.1|refseq:NP_005355.2|refseq:XP_016885009.1|ensembl:ENSP00000286482|ensembl:ENSP00000438293|ensembl:ENSP00000443776|ensembl:ENSG00000156009(gene)|ensembl:ENST00000286482(transcript)|ensembl:ENST00000535454(transcript)|ensembl:ENST00000542674(transcript)|interpro:IPR002190(MAGE protein)|interpro:IPR021072|interpro:IPR030095|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899	-	crc64:81A1CB33134BC559	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:BlL3W6HUN+uAKF/AxwlV1zT5YZQ559292	rogid:Qz29eM5nzFfUZl/DBtBcdhGQBNE9606	intact-crc:1D35769249894691|rigid:VTbvHt8oLrIEYWwXe7e88GF4gGE	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
intact:EBI-11522208	uniprotkb:P43358	-	intact:EBI-743122|ensembl:ENSP00000276344|ensembl:ENSP00000353379|ensembl:ENSP00000359360|ensembl:ENSP00000359365|ensembl:ENSP00000377497|ensembl:ENSP00000377498|ensembl:ENSP00000394149|ensembl:ENSP00000402186|ensembl:ENSP00000506838|ensembl:ENSP00000507023|uniprotkb:Q14798	psi-mi:ylr445w(display_short)|psi-mi:EBI-11522208(display_long)	psi-mi:maga4_human(display_long)|uniprotkb:MAGE-4 antigen(gene name synonym)|uniprotkb:MAGE-X2 antigen(gene name synonym)|uniprotkb:MAGE-41 antigen(gene name synonym)|uniprotkb:Cancer/testis antigen 1.4(gene name synonym)|uniprotkb:MAGEA4(gene name)|psi-mi:MAGEA4(display_short)|uniprotkb:MAGE4(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550020|imex:IM-24995-3076	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSG00000147381(gene)|ensembl:ENST00000276344(transcript)|ensembl:ENST00000360243(transcript)|ensembl:ENST00000370335(transcript)|ensembl:ENST00000370340(transcript)|ensembl:ENST00000393920(transcript)|ensembl:ENST00000393921(transcript)|ensembl:ENST00000430273(transcript)|ensembl:ENST00000457310(transcript)|ensembl:ENST00000682265(transcript)|ensembl:ENST00000684668(transcript)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045787"(positive regulation of cell cycle)|interpro:IPR002190(MAGE protein)|interpro:IPR021072|interpro:IPR030098|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|mint:P43358|rcsb pdb:1I4F|rcsb pdb:2WA0|rcsb pdb:6TRN|rcsb pdb:6TRO|refseq:NP_001011548.1|refseq:NP_001011549.1|refseq:NP_001011550.1|refseq:NP_002353.3|refseq:XP_005274735.1|refseq:XP_005274736.1	-	no-uniprot-update:	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:kUe7etYjGLH6i6KZ5N2LXUnjAf04932	rogid:wF193QbpesCr14OlGMQD+BabWvs9606	intact-crc:14A2CDA8A2BB0A6A|rigid:MdsWg7Q3c+qYxXgxDIdBhk0IZso	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P32502	uniprotkb:P43356	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	intact:EBI-5650739|uniprotkb:A8K328|uniprotkb:Q32NC6|ensembl:ENSP00000333487|ensembl:ENSP00000359316|ensembl:ENSP00000469919|ensembl:ENSP00000470872|ensembl:ENSP00000480491|ensembl:ENSP00000480738|ensembl:ENSP00000484290|ensembl:ENSP00000485391|ensembl:ENSP00000485541|ensembl:ENSP00000507594|ensembl:ENSP00000507899	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:maga2_human(display_long)|uniprotkb:MAGEA2(gene name)|psi-mi:MAGEA2(display_short)|uniprotkb:MAGEA2B(gene name)|psi-mi:MAGEA2B(display_short)|uniprotkb:MAGE2(gene name synonym)|uniprotkb:MAGEA2A(gene name synonym)|uniprotkb:MAGE2(gene name synonym)|uniprotkb:MAGEA2(gene name synonym)|uniprotkb:Cancer/testis antigen 1.2(gene name synonym)|uniprotkb:MAGE-2 antigen(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550016|imex:IM-24995-3075	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731	refseq:NP_001269430.1|refseq:NP_001269431.1|refseq:NP_001269433.1|refseq:NP_001269434.1|refseq:NP_001308329.1|refseq:NP_001308330.1|refseq:NP_001308331.1|refseq:NP_001308332.1|refseq:NP_001308333.1|refseq:NP_005352.1|refseq:NP_705692.1|refseq:NP_786884.1|refseq:NP_786885.1|dip:DIP-61231N|refseq:XP_016884895.1|refseq:XP_016885008.1|ensembl:ENSG00000183305(gene)|ensembl:ENSG00000268606(gene)|ensembl:ENST00000331220(transcript)|ensembl:ENST00000370293(transcript)|ensembl:ENST00000595583(transcript)|ensembl:ENST00000598543(transcript)|ensembl:ENST00000611557(transcript)|ensembl:ENST00000611674(transcript)|ensembl:ENST00000620710(transcript)|ensembl:ENST00000623438(transcript)|ensembl:ENST00000623806(transcript)|ensembl:ENST00000682532(transcript)|ensembl:ENST00000684311(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0016605"(PML body)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0033234"(negative regulation of protein sumoylation)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0044257"(cellular protein catabolic process)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0072331"(signal transduction by p53 class mediator)|go:"GO:0090398"(cellular senescence)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901984"(negative regulation of protein acetylation)|interpro:IPR002190(MAGE protein)|interpro:IPR021072|interpro:IPR030103|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899	-	crc64:A5409FAF1594854C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	rogid:aYv4+irEk9vGE2f3yZQR8hCQGec9606	intact-crc:405164235CF55022|rigid:4uhle33EU3ueWB3NIALf2R+j2dM	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P28004	uniprotkb:P43365	intact:EBI-20640|uniprotkb:D6VPI6|ensemblfungi:YAL032C	intact:EBI-749530|uniprotkb:Q9NSD3|intact:EBI-10178394|uniprotkb:Q6FHH8|ensembl:ENSP00000350592|ensembl:ENSP00000377447|ensembl:ENSP00000377478	psi-mi:prp45_yeast(display_long)|uniprotkb:YAL032C(locus name)|uniprotkb:PRP45(gene name)|psi-mi:PRP45(display_short)|uniprotkb:FUN20(gene name synonym)	psi-mi:magac_human(display_long)|uniprotkb:MAGE-12 antigen(gene name synonym)|uniprotkb:MAGE12F antigen(gene name synonym)|uniprotkb:Cancer/testis antigen 1.12(gene name synonym)|uniprotkb:MAGEA12(gene name)|psi-mi:MAGEA12(display_short)|uniprotkb:MAGE12(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550028|imex:IM-24995-3078	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009370.1|sgd:S000000030|ensemblfungi:YAL032C(gene)|ensemblfungi:YAL032C_mRNA(transcript)|go:"GO:0000350"(generation of catalytic spliceosome for second transesterification step)|go:"GO:0005634"(nucleus)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|interpro:IPR004015(SKIP/SNW)|interpro:IPR017862|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|dip:DIP-2774N|mint:P28004	refseq:NP_001159858.1|refseq:NP_001159859.1|refseq:NP_005358.2|ensembl:ENSG00000213401(gene)|ensembl:ENST00000357916(transcript)|ensembl:ENST00000393869(transcript)|ensembl:ENST00000393900(transcript)|interpro:IPR002190(MAGE protein)|interpro:IPR021072|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899	-	crc64:FE5A724186D7FE84	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:qoHF1UsO3k+JOTOfigSuy2P84/k559292	rogid:3/Jxz2VsFOb67RWqWj3xbTrw3s49606	intact-crc:FAD12C3F2A553B49|rigid:G+FbStO3V9B8noWIKuGba0HFTkE	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P46948	uniprotkb:Q08379	intact:EBI-1788|uniprotkb:D6VUX7|ensemblfungi:YGR195W	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	psi-mi:rrp41_yeast(display_long)|uniprotkb:SKI6(gene name)|psi-mi:SKI6(display_short)|uniprotkb:YGR195W(locus name)|uniprotkb:G7587(orf name)|uniprotkb:ECM20(gene name synonym)|uniprotkb:Ribosomal RNA-processing protein 41(gene name synonym)|uniprotkb:Superkiller protein 6(gene name synonym)|uniprotkb:Extracellular mutant protein 20(gene name synonym)|uniprotkb:RRP41(gene name synonym)	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550084|imex:IM-24995-3092	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003427|refseq:NP_011711.3|dip:DIP-2083N|mint:P46948|ensemblfungi:YGR195W(gene)|ensemblfungi:YGR195W_mRNA(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034473"(U1 snRNA 3'-end processing)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0034476"(U5 snRNA 3'-end processing)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071039"(nuclear polyadenylation-dependent CUT catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345|rcsb pdb:2WP8|rcsb pdb:4IFD|rcsb pdb:4OO1|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5G06|rcsb pdb:5JEA|rcsb pdb:5K36|rcsb pdb:5OKZ|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-429958|reactome:R-SCE-450385|reactome:R-SCE-450513|reactome:R-SCE-6791226	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N	-	crc64:C80EFFB528A43044	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2017/05/26	rogid:I7vEo0EUB1jZO+3v12H0LwVbgmo559292	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	intact-crc:61473D9417A7886C|rigid:aYVsQbvOuS0rfHAKF/pT/tJUV3E	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P20807-4	uniprotkb:P46948	intact:EBI-11532021|ensembl:ENSP00000380384	intact:EBI-1788|uniprotkb:D6VUX7|ensemblfungi:YGR195W	psi-mi:p20807-4(display_long)|uniprotkb:CAPN3(gene name)|psi-mi:CAPN3(display_short)|uniprotkb:CANP3(gene name synonym)|uniprotkb:CANPL3(gene name synonym)|uniprotkb:Calcium-activated neutral proteinase 3(gene name synonym)|uniprotkb:Calpain L3(gene name synonym)|uniprotkb:Calpain p94(gene name synonym)|uniprotkb:Muscle-specific calcium-activated neutral protease 3(gene name synonym)|uniprotkb:NCL1(gene name synonym)|uniprotkb:New calpain 1(gene name synonym)	psi-mi:rrp41_yeast(display_long)|uniprotkb:SKI6(gene name)|psi-mi:SKI6(display_short)|uniprotkb:YGR195W(locus name)|uniprotkb:G7587(orf name)|uniprotkb:ECM20(gene name synonym)|uniprotkb:Ribosomal RNA-processing protein 41(gene name synonym)|uniprotkb:Superkiller protein 6(gene name synonym)|uniprotkb:Extracellular mutant protein 20(gene name synonym)|uniprotkb:RRP41(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550080|imex:IM-24995-3091	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-5655000(isoform-parent)|uniprotkb:P20807-4(isoform-parent)|ensembl:ENSG00000092529(gene)|ensembl:ENST00000397200(transcript)	sgd:S000003427|refseq:NP_011711.3|dip:DIP-2083N|mint:P46948|ensemblfungi:YGR195W(gene)|ensemblfungi:YGR195W_mRNA(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034473"(U1 snRNA 3'-end processing)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0034476"(U5 snRNA 3'-end processing)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071039"(nuclear polyadenylation-dependent CUT catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345|rcsb pdb:2WP8|rcsb pdb:4IFD|rcsb pdb:4OO1|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5G06|rcsb pdb:5JEA|rcsb pdb:5K36|rcsb pdb:5OKZ|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-429958|reactome:R-SCE-450385|reactome:R-SCE-450513|reactome:R-SCE-6791226	-	-	crc64:C80EFFB528A43044	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:6TrGg2jigHr0xYLsxBNCLjAl3J89606	rogid:I7vEo0EUB1jZO+3v12H0LwVbgmo559292	intact-crc:798B68FFE7E563E4|rigid:qR8dwfZsFl11ZR3gc4ETCIgmcEc	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P46680	uniprotkb:P40123	intact:EBI-2406|uniprotkb:D6VZR5|ensemblfungi:YMR092C	intact:EBI-1051165|uniprotkb:Q6IAY2|uniprotkb:B2R5Y3|intact:EBI-11045298|uniprotkb:B7Z1C4|uniprotkb:B7Z214|ensembl:ENSP00000229922	psi-mi:aip1_yeast(display_long)|uniprotkb:AIP1(gene name)|psi-mi:AIP1(display_short)|uniprotkb:YM9582.17C(orf name)|uniprotkb:YMR092C(locus name)	psi-mi:cap2_human(display_long)|uniprotkb:CAP2(gene name)|psi-mi:CAP2(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550076|imex:IM-24995-3090	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013810.1|sgd:S000004698|reactome:R-SCE-114608|dip:DIP-890N|ensemblfungi:YMR092C(gene)|ensemblfungi:YMR092C_mRNA(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005884"(actin filament)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030479"(actin cortical patch)|go:"GO:0030836"(positive regulation of actin filament depolymerization)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032466"(negative regulation of cytokinesis)|go:"GO:0043332"(mating projection tip)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|rcsb pdb:1PGU|rcsb pdb:1PI6	refseq:NP_006357.1|ensembl:ENSG00000112186(gene)|ensembl:ENST00000229922(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007165"(signal transduction)|go:"GO:0007190"(activation of adenylate cyclase activity)|go:"GO:0008179"(adenylate cyclase binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0042802"(identical protein binding)|go:"GO:0045761"(regulation of adenylate cyclase activity)|interpro:IPR001837(Adenylate cyclase-associated CAP)|interpro:IPR006599(CARP motif)|interpro:IPR013912(Adenylate cyclase-associated CAP,  C-terminal)|interpro:IPR013992(Adenylate cyclase-associated CAP, N-terminal)|interpro:IPR016098(Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal)|interpro:IPR017901|interpro:IPR018106|interpro:IPR028417|interpro:IPR028418|interpro:IPR036222|interpro:IPR036223|reactome:R-HSA-428890|go:"GO:0005886"(plasma membrane)	-	crc64:B8340BF68DD08257	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:TwLC/U+xqc7crYws+782F2f1rEo559292	rogid:+B9t0sirXq7xJD3kZIlab7KBR9Y9606	intact-crc:C0DAC63C8B0D2CD9|rigid:zfnwVDYx+4fpyXqpylfzXnZz11k	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P23285	uniprotkb:P46379-2	intact:EBI-5448|uniprotkb:D3DL06|ensemblfungi:YHR057C	intact:EBI-10988864|ensembl:ENSP00000211379|ensembl:ENSP00000365143|ensembl:ENSP00000372938|ensembl:ENSP00000372940|ensembl:ENSP00000389121|ensembl:ENSP00000410156|ensembl:ENSP00000412110|ensembl:ENSP00000413698	psi-mi:cypb_yeast(display_long)|uniprotkb:CYP2(gene name synonym)|uniprotkb:YHR057C(locus name)|uniprotkb:CPR2(gene name)|psi-mi:CPR2(display_short)|uniprotkb:CRG(gene name synonym)|uniprotkb:SCC2(gene name synonym)|uniprotkb:Cyclophilin B(gene name synonym)|uniprotkb:Cyclophilin-related protein(gene name synonym)|uniprotkb:Rotamase B(gene name synonym)	psi-mi:p46379-2(display_long)|uniprotkb:BAG6(gene name)|psi-mi:BAG6(display_short)|uniprotkb:BAG family molecular chaperone regulator 6(gene name synonym)|uniprotkb:BAT3(gene name synonym)|uniprotkb:BCL2-associated athanogene 6(gene name synonym)|uniprotkb:G3(gene name synonym)|uniprotkb:HLA-B-associated transcript 3(gene name synonym)|uniprotkb:Protein G3(gene name synonym)|uniprotkb:Protein Scythe(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550072|imex:IM-24995-3089	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011924.1|sgd:S000001099|dip:DIP-1280N|ensemblfungi:YHR057C(gene)|ensemblfungi:YHR057C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006457"(protein folding)|go:"GO:0016018"(cyclosporin A binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|interpro:IPR020892|interpro:IPR024936|interpro:IPR029000	intact:EBI-347552(isoform-parent)|uniprotkb:P46379-2(isoform-parent)|ensembl:ENSG00000096155(gene)|ensembl:ENSG00000204463(gene)|ensembl:ENSG00000229524(gene)|ensembl:ENSG00000233348(gene)|ensembl:ENST00000211379(transcript)|ensembl:ENST00000375976(transcript)|ensembl:ENST00000383446(transcript)|ensembl:ENST00000383448(transcript)|ensembl:ENST00000417144(transcript)|ensembl:ENST00000419847(transcript)|ensembl:ENST00000442479(transcript)|ensembl:ENST00000443182(transcript)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:jKSwBj1KpYZTRNaWOrKxCwC0rAY559292	rogid:7y9hxqfcTmnCBRON6qNoHPCdODY9606	intact-crc:8B74BDD0F051EC95|rigid:GJevR6h5GvKTdi1t8sJsrw+dIgE	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P43569	uniprotkb:O43639	intact:EBI-22808|uniprotkb:D6VTK2|ensemblfungi:YFL028C	intact:EBI-713635|uniprotkb:Q9BWN9|uniprotkb:Q9UIC3|ensembl:ENSP00000233154|ensembl:ENSP00000377018|uniprotkb:D3DVK1	psi-mi:caf16_yeast(display_long)|uniprotkb:CAF16(gene name)|psi-mi:CAF16(display_short)|uniprotkb:YFL028C(locus name)	psi-mi:nck2_human(display_long)|uniprotkb:NCK adaptor protein 2(gene name synonym)|uniprotkb:SH2/SH3 adaptor protein NCK-beta(gene name synonym)|uniprotkb:NCK2(gene name)|psi-mi:NCK2(display_short)|uniprotkb:GRB4(gene name synonym)|uniprotkb:Growth factor receptor-bound protein 4(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550048|imex:IM-24995-3083	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_116625.1|sgd:S000001866|dip:DIP-5946N|ensemblfungi:YFL028C(gene)|ensemblfungi:YFL028C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0030014"(CCR4-NOT complex)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR027417	refseq:XP_006712860.1|refseq:NP_001004720.1|refseq:NP_003572.2|ensembl:ENSG00000071051(gene)|ensembl:ENST00000233154(transcript)|ensembl:ENST00000393349(transcript)|go:"GO:0001771"(immunological synapse formation)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0007015"(actin filament organization)|go:"GO:0007165"(signal transduction)|go:"GO:0007172"(signal complex assembly)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007176"(regulation of epidermal growth factor-activated receptor activity)|go:"GO:0008093"(cytoskeletal anchor activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0012506"(vesicle membrane)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016477"(cell migration)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0036493"(positive regulation of translation in response to endoplasmic reticulum stress)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042110"(T cell activation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0060996"(dendritic spine development)|go:"GO:0097110"(scaffold protein binding)|go:"GO:1902237"(positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903898"(negative regulation of PERK-mediated unfolded protein response)|go:"GO:1903912"(negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation)|go:"GO:1990441"(negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR017304(Cytoplasmic, NCK)|interpro:IPR028524|interpro:IPR035559|interpro:IPR035560|interpro:IPR035561|interpro:IPR035883|interpro:IPR036028|interpro:IPR036860|mint:O43639|rcsb pdb:1U5S|rcsb pdb:1WX6|rcsb pdb:1Z3K|rcsb pdb:2B86|rcsb pdb:2CIA|rcsb pdb:2FRW|rcsb pdb:2FRY|rcsb pdb:2JXB|rcsb pdb:4E6R|reactome:R-HSA-186763|reactome:R-HSA-373753|reactome:R-HSA-3928664|reactome:R-HSA-428540|reactome:R-HSA-4420097|reactome:R-HSA-8985801|reactome:R-HSA-9013420|reactome:R-HSA-9013424|refseq:XP_016860592.1|refseq:XP_016860593.1|refseq:XP_016860594.1|refseq:XP_011510293.1	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:TEaj2ClpUSgtlaILtvQi9v5zB6A559292	rogid:WV9nJ78Im/ga5KQlRuSN2ODzWpQ9606	intact-crc:B2DB8E6F99A1B7E9|rigid:GAqQ92YJyTpMzbs4uDUGVOhHZZ0	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P43552	uniprotkb:P46379-2	intact:EBI-22855|uniprotkb:D6VTH9|ensemblfungi:YFL051C	intact:EBI-10988864|ensembl:ENSP00000211379|ensembl:ENSP00000365143|ensembl:ENSP00000372938|ensembl:ENSP00000372940|ensembl:ENSP00000389121|ensembl:ENSP00000410156|ensembl:ENSP00000412110|ensembl:ENSP00000413698	psi-mi:yff1_yeast(display_long)|uniprotkb:YFL051C(locus name)	psi-mi:p46379-2(display_long)|uniprotkb:BAG6(gene name)|psi-mi:BAG6(display_short)|uniprotkb:BAG family molecular chaperone regulator 6(gene name synonym)|uniprotkb:BAT3(gene name synonym)|uniprotkb:BCL2-associated athanogene 6(gene name synonym)|uniprotkb:G3(gene name synonym)|uniprotkb:HLA-B-associated transcript 3(gene name synonym)|uniprotkb:Protein G3(gene name synonym)|uniprotkb:Protein Scythe(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550064|imex:IM-24995-3087	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_116576.1|sgd:S000001843|dip:DIP-4270N|ensemblfungi:YFL051C(gene)|ensemblfungi:YFL051C_mRNA(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)	intact:EBI-347552(isoform-parent)|uniprotkb:P46379-2(isoform-parent)|ensembl:ENSG00000096155(gene)|ensembl:ENSG00000204463(gene)|ensembl:ENSG00000229524(gene)|ensembl:ENSG00000233348(gene)|ensembl:ENST00000211379(transcript)|ensembl:ENST00000375976(transcript)|ensembl:ENST00000383446(transcript)|ensembl:ENST00000383448(transcript)|ensembl:ENST00000417144(transcript)|ensembl:ENST00000419847(transcript)|ensembl:ENST00000442479(transcript)|ensembl:ENST00000443182(transcript)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:oiB9m73Dyv5h04x667Dlwx3MiC8559292	rogid:7y9hxqfcTmnCBRON6qNoHPCdODY9606	intact-crc:3DECBE28435DB8E5|rigid:1YisNh/uvaM61W64I65X41K4b1E	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P43618	uniprotkb:O95198	intact:EBI-23036|uniprotkb:D6VTS9|uniprotkb:Q6B2K8|ensemblfungi:YFR046C	intact:EBI-746999|uniprotkb:B2RD18|uniprotkb:Q8N484|uniprotkb:Q8TBH5|uniprotkb:A6NCM7|uniprotkb:B4DFH7|uniprotkb:F5H6M3|ensembl:ENSP00000226725	psi-mi:cenpt_yeast(display_long)|uniprotkb:CNN1(gene name)|psi-mi:CNN1(display_short)|uniprotkb:Co-purified with NNF1 protein 1(gene name synonym)|uniprotkb:CENP-T homolog(gene name synonym)|uniprotkb:Constitutive centromere-associated network protein CNN1(gene name synonym)|uniprotkb:YFR046C(locus name)	psi-mi:klhl2_human(display_long)|uniprotkb:Actin-binding protein Mayven(gene name synonym)|uniprotkb:KLHL2(gene name)|psi-mi:KLHL2(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550060|imex:IM-24995-3086	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000001942|refseq:NP_116704.1|dip:DIP-5186N|ensemblfungi:YFR046C(gene)|ensemblfungi:YFR046C_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0019237"(centromeric DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051301"(cell division)|go:"GO:1901720"(negative regulation of NMS complex assembly)|rcsb pdb:4GEQ|rcsb pdb:6WUC|rcsb pdb:6YPC	refseq:NP_001154993.1|refseq:NP_001154994.1|refseq:NP_009177.3|refseq:NP_001317952.1|refseq:NP_001317953.1|refseq:XP_016863165.1|ensembl:ENSG00000109466(gene)|ensembl:ENST00000226725(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030027"(lamellipodium)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR017096(Kelch-like protein, gigaxonin)|interpro:IPR044072|mint:O95198|rcsb pdb:2XN4|rcsb pdb:4CHB|reactome:R-HSA-8951664|reactome:R-HSA-983168|go:"GO:0042802"(identical protein binding)	-	crc64:48CEEC087A056D42	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Pkvt7uOWT2WqZlcWh8NeZH67Mvs559292	rogid:tFegR2lJZccRqs4qUjdT3PNjNnk9606	intact-crc:7B7F968AB97DFCB0|rigid:r9OW5JqnvYns5Kl5S88NI9Ly1nM	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P19012	uniprotkb:P43592	intact:EBI-739566|uniprotkb:Q53XV8|uniprotkb:Q9BUG4|uniprotkb:B3KQY1|uniprotkb:B3KRA2|uniprotkb:E0CX14|ensembl:ENSP00000254043|ensembl:ENSP00000377546	intact:EBI-22932|uniprotkb:D6VTN8|ensemblfungi:YFR008W	psi-mi:k1c15_human(display_long)|uniprotkb:KRT15(gene name)|psi-mi:KRT15(display_short)|uniprotkb:KRTB(gene name synonym)|uniprotkb:Cytokeratin-15(gene name synonym)|uniprotkb:Keratin-15(gene name synonym)	psi-mi:far7_yeast(display_long)|uniprotkb:YFR008W(locus name)|uniprotkb:FAR7(gene name)|psi-mi:FAR7(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550056|imex:IM-24995-3085	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002266.2|ensembl:ENSG00000171346(gene)|ensembl:ENST00000254043(transcript)|ensembl:ENST00000393976(transcript)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0008544"(epidermis development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097110"(scaffold protein binding)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR039008|mint:P19012|reactome:R-HSA-6805567|reactome:R-HSA-6809371	sgd:S000001904|refseq:NP_116663.1|dip:DIP-1315N|mint:P43592|ensemblfungi:YFR008W(gene)|ensemblfungi:YFR008W_mRNA(transcript)|go:"GO:0000321"(re-entry into mitotic cell cycle after pheromone arrest)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)	-	-	crc64:81156978FF7AAD54	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:WrZQBYQvrWcfrR5ojWXrXp6spPE9606	rogid:RB7IaPAzOtEtryalHHz8psxOYqw559292	intact-crc:6CACAC07D760F7AE|rigid:iFW+ndIy4CRKN6qrfc80CuyYFAE	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O95751	uniprotkb:P43592	intact:EBI-740738|ensembl:ENSP00000359557|uniprotkb:Q6IAR6	intact:EBI-22932|uniprotkb:D6VTN8|ensemblfungi:YFR008W	psi-mi:ldoc1_human(display_long)|uniprotkb:Leucine zipper protein down-regulated in cancer cells(gene name synonym)|uniprotkb:LDOC1(gene name)|psi-mi:LDOC1(display_short)|uniprotkb:BCUR1(gene name synonym)	psi-mi:far7_yeast(display_long)|uniprotkb:YFR008W(locus name)|uniprotkb:FAR7(gene name)|psi-mi:FAR7(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550052|imex:IM-24995-3084	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_036449.1|ensembl:ENSG00000182195(gene)|ensembl:ENST00000370526(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071225"(cellular response to muramyl dipeptide)|interpro:IPR032549|interpro:IPR032567	sgd:S000001904|refseq:NP_116663.1|dip:DIP-1315N|mint:P43592|ensemblfungi:YFR008W(gene)|ensemblfungi:YFR008W_mRNA(transcript)|go:"GO:0000321"(re-entry into mitotic cell cycle after pheromone arrest)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)	-	-	crc64:81156978FF7AAD54	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Ediu0oNiZ/+YVY8l3fNdgP5A+v09606	rogid:RB7IaPAzOtEtryalHHz8psxOYqw559292	intact-crc:B2BF0724E2E3E32C|rigid:O7PdVOCZde1KYP3b4BIZbVVrlrE	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P35176	uniprotkb:P46379-2	intact:EBI-5458|uniprotkb:D6VST3|ensemblfungi:YDR304C	intact:EBI-10988864|ensembl:ENSP00000211379|ensembl:ENSP00000365143|ensembl:ENSP00000372938|ensembl:ENSP00000372940|ensembl:ENSP00000389121|ensembl:ENSP00000410156|ensembl:ENSP00000412110|ensembl:ENSP00000413698	psi-mi:cypd_yeast(display_long)|uniprotkb:CPR5(gene name)|psi-mi:CPR5(display_short)|uniprotkb:YDR304C(locus name)|uniprotkb:D9740.14(orf name)|uniprotkb:CYP5(gene name synonym)|uniprotkb:CYPD(gene name synonym)|uniprotkb:Cyclophilin D(gene name synonym)|uniprotkb:Rotamase D(gene name synonym)	psi-mi:p46379-2(display_long)|uniprotkb:BAG6(gene name)|psi-mi:BAG6(display_short)|uniprotkb:BAG family molecular chaperone regulator 6(gene name synonym)|uniprotkb:BAT3(gene name synonym)|uniprotkb:BCL2-associated athanogene 6(gene name synonym)|uniprotkb:G3(gene name synonym)|uniprotkb:HLA-B-associated transcript 3(gene name synonym)|uniprotkb:Protein G3(gene name synonym)|uniprotkb:Protein Scythe(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550068|imex:IM-24995-3088	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002712|refseq:NP_010590.3|dip:DIP-5222N|mint:P35176|ensemblfungi:YDR304C(gene)|ensemblfungi:YDR304C_mRNA(transcript)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006457"(protein folding)|go:"GO:0016018"(cyclosporin A binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|interpro:IPR020892|interpro:IPR029000	intact:EBI-347552(isoform-parent)|uniprotkb:P46379-2(isoform-parent)|ensembl:ENSG00000096155(gene)|ensembl:ENSG00000204463(gene)|ensembl:ENSG00000229524(gene)|ensembl:ENSG00000233348(gene)|ensembl:ENST00000211379(transcript)|ensembl:ENST00000375976(transcript)|ensembl:ENST00000383446(transcript)|ensembl:ENST00000383448(transcript)|ensembl:ENST00000417144(transcript)|ensembl:ENST00000419847(transcript)|ensembl:ENST00000442479(transcript)|ensembl:ENST00000443182(transcript)	-	crc64:F4861424C8443B58	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:aCn3loYoSVWfy5Tb5i+MsOHcUEo559292	rogid:7y9hxqfcTmnCBRON6qNoHPCdODY9606	intact-crc:390C41894C0A0825|rigid:yPAhK57/pKkWvoSCATzZn63M5Oo	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P47094	uniprotkb:O43765	intact:EBI-26323|ensemblfungi:YJR023C	intact:EBI-347996|ensembl:ENSP00000221566|ensembl:ENSP00000503397|ensembl:ENSP00000504495|uniprotkb:Q9BTZ9|intact:EBI-1045243|uniprotkb:Q6FIA9|uniprotkb:D6W610	psi-mi:yjz3_yeast(display_long)|uniprotkb:J1470(orf name)|uniprotkb:YJR83.19(orf name)|uniprotkb:YJR023C(locus name)	psi-mi:sgta_human(display_long)|uniprotkb:SGTA(gene name)|psi-mi:SGTA(display_short)|uniprotkb:SGT(gene name synonym)|uniprotkb:Alpha-SGT(gene name synonym)|uniprotkb:Vpu-binding protein(gene name synonym)|uniprotkb:SGT1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550120|imex:IM-24995-3101	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003784|dip:DIP-2641N|ensemblfungi:YJR023C(gene)|ensemblfungi:YJR023C_mRNA(transcript)|go:"GO:0016021"(integral component of membrane)	rcsb pdb:4CPG|rcsb pdb:4GOD|rcsb pdb:4GOE|rcsb pdb:4GOF|reactome:R-HSA-9609523|rcsb pdb:2VYI|ensembl:ENSG00000104969(gene)|ensembl:ENST00000221566(transcript)|ensembl:ENST00000676943(transcript)|ensembl:ENST00000677149(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072380"(TRC complex)|go:"GO:0098850"(extrinsic component of synaptic vesicle membrane)|go:"GO:1903070"(negative regulation of ER-associated ubiquitin-dependent protein catabolic process)|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)|go:"GO:1903646"(positive regulation of chaperone-mediated protein folding)|go:"GO:1904288"(BAT3 complex binding)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR032374|mint:O43765|refseq:XP_011526480.1|refseq:NP_003012.1	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:lOcQ5QyAEpXz/uROltQZ2quCgzI559292	rogid:r/Cyj4UJk/cS8QdrbjhTZMPCigI9606	intact-crc:F3FB012095A4286D|rigid:xIqeVpaNWZvv+ifhaApFY44L+H4	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P19012	uniprotkb:P47041	intact:EBI-739566|uniprotkb:Q53XV8|uniprotkb:Q9BUG4|uniprotkb:B3KQY1|uniprotkb:B3KRA2|uniprotkb:E0CX14|ensembl:ENSP00000254043|ensembl:ENSP00000377546	intact:EBI-25889|uniprotkb:D6VWC4|ensemblfungi:YJL058C	psi-mi:k1c15_human(display_long)|uniprotkb:KRT15(gene name)|psi-mi:KRT15(display_short)|uniprotkb:KRTB(gene name synonym)|uniprotkb:Cytokeratin-15(gene name synonym)|uniprotkb:Keratin-15(gene name synonym)	psi-mi:bit61_yeast(display_long)|uniprotkb:YJL058C(locus name)|uniprotkb:J1141(orf name)|uniprotkb:61 kDa binding partner of TOR2 protein(gene name synonym)|uniprotkb:BIT61(gene name)|psi-mi:BIT61(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550116|imex:IM-24995-3100	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002266.2|ensembl:ENSG00000171346(gene)|ensembl:ENST00000254043(transcript)|ensembl:ENST00000393976(transcript)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0008544"(epidermis development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097110"(scaffold protein binding)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR039008|mint:P19012|reactome:R-HSA-6805567|reactome:R-HSA-6809371	refseq:NP_012477.1|sgd:S000003594|dip:DIP-1444N|reactome:R-SCE-1257604|reactome:R-SCE-389357|reactome:R-SCE-5218920|ensemblfungi:YJL058C(gene)|ensemblfungi:YJL058C_mRNA(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005737"(cytoplasm)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0031932"(TORC2 complex)|go:"GO:0038203"(TORC2 signaling)|go:"GO:0071944"(cell periphery)|interpro:IPR013745(HbrB-like)|reactome:R-SCE-6804757	-	-	crc64:99F0F96840311F4B	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:WrZQBYQvrWcfrR5ojWXrXp6spPE9606	rogid:H+zcKwbWL90wsmvD9TfWYmEbRwM559292	intact-crc:A51237A6288562B6|rigid:6HX1d/7oa0CN5IOpc0gDYAlr24c	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q08379	uniprotkb:P47041	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	intact:EBI-25889|uniprotkb:D6VWC4|ensemblfungi:YJL058C	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:bit61_yeast(display_long)|uniprotkb:YJL058C(locus name)|uniprotkb:J1141(orf name)|uniprotkb:61 kDa binding partner of TOR2 protein(gene name synonym)|uniprotkb:BIT61(gene name)|psi-mi:BIT61(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550112|imex:IM-24995-3099	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N	refseq:NP_012477.1|sgd:S000003594|dip:DIP-1444N|reactome:R-SCE-1257604|reactome:R-SCE-389357|reactome:R-SCE-5218920|ensemblfungi:YJL058C(gene)|ensemblfungi:YJL058C_mRNA(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005737"(cytoplasm)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0031932"(TORC2 complex)|go:"GO:0038203"(TORC2 signaling)|go:"GO:0071944"(cell periphery)|interpro:IPR013745(HbrB-like)|reactome:R-SCE-6804757	-	-	crc64:99F0F96840311F4B	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2017/05/26	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	rogid:H+zcKwbWL90wsmvD9TfWYmEbRwM559292	intact-crc:70AC75C6B05147B6|rigid:yqQ5oEjpGHrzS/87teheWUEjnyw	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P47041	uniprotkb:P14136	intact:EBI-25889|uniprotkb:D6VWC4|ensemblfungi:YJL058C	intact:EBI-744302|uniprotkb:Q53H98|uniprotkb:Q5D055|uniprotkb:Q6ZQS3|uniprotkb:Q7Z5J6|uniprotkb:Q7Z5J7|uniprotkb:Q96KS4|uniprotkb:Q96P18|uniprotkb:Q9UFD0|uniprotkb:B2RD44|uniprotkb:D3DX59|intact:EBI-3909365|uniprotkb:E9PAX3|ensembl:ENSP00000466598|uniprotkb:A7REI1	psi-mi:bit61_yeast(display_long)|uniprotkb:YJL058C(locus name)|uniprotkb:J1141(orf name)|uniprotkb:61 kDa binding partner of TOR2 protein(gene name synonym)|uniprotkb:BIT61(gene name)|psi-mi:BIT61(display_short)	psi-mi:gfap_human(display_long)|uniprotkb:GFAP(gene name)|psi-mi:GFAP(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550108|imex:IM-24995-3098	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012477.1|sgd:S000003594|dip:DIP-1444N|reactome:R-SCE-1257604|reactome:R-SCE-389357|reactome:R-SCE-5218920|ensemblfungi:YJL058C(gene)|ensemblfungi:YJL058C_mRNA(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005737"(cytoplasm)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0031932"(TORC2 complex)|go:"GO:0038203"(TORC2 signaling)|go:"GO:0071944"(cell periphery)|interpro:IPR013745(HbrB-like)|reactome:R-SCE-6804757	refseq:NP_001124491.1|refseq:NP_001229305.1|refseq:NP_002046.1|ensembl:ENSG00000131095(gene)|ensembl:ENST00000588735(transcript)|go:"GO:0005178"(integrin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0009611"(response to wounding)|go:"GO:0010467"(gene expression)|go:"GO:0010625"(positive regulation of Schwann cell proliferation)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0014002"(astrocyte development)|go:"GO:0019900"(kinase binding)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0031102"(neuron projection regeneration)|go:"GO:0042802"(identical protein binding)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0044297"(cell body)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0051580"(regulation of neurotransmitter uptake)|go:"GO:0060020"(Bergmann glial cell differentiation)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0070779"(D-aspartate import across plasma membrane)|go:"GO:0097450"(astrocyte end-foot)|go:"GO:0098574"(cytoplasmic side of lysosomal membrane)|go:"GO:1904714"(regulation of chaperone-mediated autophagy)|interpro:IPR006821(Intermediate filament, DNA-binding region)|interpro:IPR018039|interpro:IPR027701|interpro:IPR039008|mint:P14136|rcsb pdb:6A9P|reactome:R-HSA-1251985|reactome:R-HSA-9613829	-	crc64:99F0F96840311F4B	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:H+zcKwbWL90wsmvD9TfWYmEbRwM559292	rogid:Pz4JW0WjMjBYILTDSX9jUmMqWhg9606	intact-crc:7079789485099084|rigid:Rk41K0v8fDB/mhKbElLL99T1QDQ	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P47041	intact:EBI-11524292	intact:EBI-25889|uniprotkb:D6VWC4|ensemblfungi:YJL058C	-	psi-mi:bit61_yeast(display_long)|uniprotkb:YJL058C(locus name)|uniprotkb:J1141(orf name)|uniprotkb:61 kDa binding partner of TOR2 protein(gene name synonym)|uniprotkb:BIT61(gene name)|psi-mi:BIT61(display_short)	psi-mi:trip6(display_short)|psi-mi:EBI-11524292(display_long)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550088|imex:IM-24995-3093	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012477.1|sgd:S000003594|dip:DIP-1444N|reactome:R-SCE-1257604|reactome:R-SCE-389357|reactome:R-SCE-5218920|ensemblfungi:YJL058C(gene)|ensemblfungi:YJL058C_mRNA(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005737"(cytoplasm)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0031932"(TORC2 complex)|go:"GO:0038203"(TORC2 signaling)|go:"GO:0071944"(cell periphery)|interpro:IPR013745(HbrB-like)|reactome:R-SCE-6804757	-	-	crc64:99F0F96840311F4B	no-uniprot-update:	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:H+zcKwbWL90wsmvD9TfWYmEbRwM559292	rogid:S6W5lkNauGhNejln9bTVoqZjNL49606	intact-crc:BB95A51D85603C3F|rigid:74ZznwJbqsjScwdu24D4Z64KWeg	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P08727	uniprotkb:P47041	intact:EBI-742756|uniprotkb:Q5XG83|uniprotkb:Q6NW33|uniprotkb:Q7L5M9|uniprotkb:Q96A53|uniprotkb:Q96FV1|uniprotkb:Q9BYF9|uniprotkb:Q9P1Y4|uniprotkb:B2R874|ensembl:ENSP00000355124	intact:EBI-25889|uniprotkb:D6VWC4|ensemblfungi:YJL058C	psi-mi:k1c19_human(display_long)|uniprotkb:Cytokeratin-19(gene name synonym)|uniprotkb:Keratin-19(gene name synonym)|uniprotkb:KRT19(gene name)|psi-mi:KRT19(display_short)	psi-mi:bit61_yeast(display_long)|uniprotkb:YJL058C(locus name)|uniprotkb:J1141(orf name)|uniprotkb:61 kDa binding partner of TOR2 protein(gene name synonym)|uniprotkb:BIT61(gene name)|psi-mi:BIT61(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550100|imex:IM-24995-3096	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002267.2|ensembl:ENSG00000171345(gene)|ensembl:ENST00000361566(transcript)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0030018"(Z disc)|go:"GO:0042383"(sarcolemma)|go:"GO:0043034"(costamere)|go:"GO:0043627"(response to estrogen)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0060706"(cell differentiation involved in embryonic placenta development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071944"(cell periphery)|go:"GO:1990357"(terminal web)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR039008|mint:P08727|reactome:R-HSA-6805567|reactome:R-HSA-6809371|dip:DIP-35655N	refseq:NP_012477.1|sgd:S000003594|dip:DIP-1444N|reactome:R-SCE-1257604|reactome:R-SCE-389357|reactome:R-SCE-5218920|ensemblfungi:YJL058C(gene)|ensemblfungi:YJL058C_mRNA(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005737"(cytoplasm)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0031932"(TORC2 complex)|go:"GO:0038203"(TORC2 signaling)|go:"GO:0071944"(cell periphery)|interpro:IPR013745(HbrB-like)|reactome:R-SCE-6804757	-	-	crc64:99F0F96840311F4B	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:fqsG2nghpcmTtI39LiYVLNYuFIA9606	rogid:H+zcKwbWL90wsmvD9TfWYmEbRwM559292	intact-crc:DD6524D10C36777F|rigid:aYJO7KBTuT1h4d2KpovFGq0CFeI	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P47041	uniprotkb:Q8N5R6	intact:EBI-25889|uniprotkb:D6VWC4|ensemblfungi:YJL058C	intact:EBI-740841|intact:EBI-953781|uniprotkb:B3KQ49|uniprotkb:A8K3U4|uniprotkb:A8MPQ6|uniprotkb:A8MV61|uniprotkb:A8MVU9|uniprotkb:Q9H5Q6|uniprotkb:Q8TAX6|intact:EBI-2320546|intact:EBI-11522976	psi-mi:bit61_yeast(display_long)|uniprotkb:YJL058C(locus name)|uniprotkb:J1141(orf name)|uniprotkb:61 kDa binding partner of TOR2 protein(gene name synonym)|uniprotkb:BIT61(gene name)|psi-mi:BIT61(display_short)	psi-mi:ccd33_human(display_long)|uniprotkb:CCDC33(gene name)|psi-mi:CCDC33(display_short)|uniprotkb:Cancer/testis antigen 61(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550096|imex:IM-24995-3095	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012477.1|sgd:S000003594|dip:DIP-1444N|reactome:R-SCE-1257604|reactome:R-SCE-389357|reactome:R-SCE-5218920|ensemblfungi:YJL058C(gene)|ensemblfungi:YJL058C_mRNA(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005737"(cytoplasm)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0031932"(TORC2 complex)|go:"GO:0038203"(TORC2 signaling)|go:"GO:0071944"(cell periphery)|interpro:IPR013745(HbrB-like)|reactome:R-SCE-6804757	refseq:NP_079331.3|interpro:IPR000008(C2 calcium-dependent membrane targeting)|go:"GO:0005777"(peroxisome)|refseq:NP_001274110.1|refseq:NP_877592.2|mint:Q8N5R6|interpro:IPR035892|interpro:IPR039889	-	crc64:99F0F96840311F4B	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2021/11/30	rogid:H+zcKwbWL90wsmvD9TfWYmEbRwM559292	rogid:eEIn7pQyfdHWx8TeLJpYy0i/gww9606	intact-crc:C99B1901118FDEE8|rigid:LPWQIXNF9ahpGT/y0LCTww/kmqU	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P47041	uniprotkb:A0A0R4J2E4	intact:EBI-25889|uniprotkb:D6VWC4|ensemblfungi:YJL058C	intact:EBI-11525602|ensembl:ENSP00000324292	psi-mi:bit61_yeast(display_long)|uniprotkb:YJL058C(locus name)|uniprotkb:J1141(orf name)|uniprotkb:61 kDa binding partner of TOR2 protein(gene name synonym)|uniprotkb:BIT61(gene name)|psi-mi:BIT61(display_short)	psi-mi:a0a0r4j2e4_human(display_long)|uniprotkb:FBF1(gene name)|psi-mi:FBF1(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550092|imex:IM-24995-3094	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012477.1|sgd:S000003594|dip:DIP-1444N|reactome:R-SCE-1257604|reactome:R-SCE-389357|reactome:R-SCE-5218920|ensemblfungi:YJL058C(gene)|ensemblfungi:YJL058C_mRNA(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005737"(cytoplasm)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0031932"(TORC2 complex)|go:"GO:0038203"(TORC2 signaling)|go:"GO:0071944"(cell periphery)|interpro:IPR013745(HbrB-like)|reactome:R-SCE-6804757	ensembl:ENSG00000188878(gene)|ensembl:ENST00000319129(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0060271"(cilium assembly)|go:"GO:0090162"(establishment of epithelial cell polarity)|go:"GO:0097539"(ciliary transition fiber)|interpro:IPR033561	-	crc64:99F0F96840311F4B	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/03/16	rogid:H+zcKwbWL90wsmvD9TfWYmEbRwM559292	rogid:N4h8foiP1+HSYZRE7i66zhtqKlQ9606	intact-crc:6093D2BC27C497FD|rigid:IpsLsdQqXZdgJahitU1+lffJJ5s	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P14373	uniprotkb:P47041	intact:EBI-719493|uniprotkb:A2BE15|uniprotkb:Q5RJA8|uniprotkb:Q5ST26|uniprotkb:Q6LA73|uniprotkb:Q6NXR9|uniprotkb:Q9BZY6|uniprotkb:Q9UJL3|ensembl:ENSP00000383555|ensembl:ENSP00000392787|ensembl:ENSP00000405229|ensembl:ENSP00000414793|ensembl:ENSP00000366404	intact:EBI-25889|uniprotkb:D6VWC4|ensemblfungi:YJL058C	psi-mi:tri27_human(display_long)|uniprotkb:TRIM27(gene name)|psi-mi:TRIM27(display_short)|uniprotkb:RNF76(gene name synonym)|uniprotkb:RFP(gene name synonym)|uniprotkb:Ret finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 27(gene name synonym)|uniprotkb:RING finger protein 76(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM27(gene name synonym)	psi-mi:bit61_yeast(display_long)|uniprotkb:YJL058C(locus name)|uniprotkb:J1141(orf name)|uniprotkb:61 kDa binding partner of TOR2 protein(gene name synonym)|uniprotkb:BIT61(gene name)|psi-mi:BIT61(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550104|imex:IM-24995-3097	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006501.1|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0090281"(negative regulation of calcium ion import)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR020457|interpro:IPR035791|interpro:IPR043136|mint:P14373|reactome:R-HSA-3232142|reactome:R-HSA-9635465|reactome:R-HSA-8948751|ensembl:ENSG00000204713(gene)|ensembl:ENSG00000215641(gene)|ensembl:ENSG00000229006(gene)|ensembl:ENSG00000234495(gene)|ensembl:ENSG00000237071(gene)|ensembl:ENST00000377199(transcript)|ensembl:ENST00000400720(transcript)|ensembl:ENST00000431123(transcript)|ensembl:ENST00000435528(transcript)|ensembl:ENST00000437160(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001650"(fibrillar center)|go:"GO:0002820"(negative regulation of adaptive immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)	refseq:NP_012477.1|sgd:S000003594|dip:DIP-1444N|reactome:R-SCE-1257604|reactome:R-SCE-389357|reactome:R-SCE-5218920|ensemblfungi:YJL058C(gene)|ensemblfungi:YJL058C_mRNA(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005737"(cytoplasm)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0031932"(TORC2 complex)|go:"GO:0038203"(TORC2 signaling)|go:"GO:0071944"(cell periphery)|interpro:IPR013745(HbrB-like)|reactome:R-SCE-6804757	-	-	crc64:99F0F96840311F4B	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:dsfH5OUghD8KSaTz1SFw9OYVTK49606	rogid:H+zcKwbWL90wsmvD9TfWYmEbRwM559292	intact-crc:B7E31D94649C0408|rigid:pFtOvJZe1d+/3DINI56Dp1R+MIE	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P48232	uniprotkb:P08727	intact:EBI-28775|uniprotkb:D6W193|ensemblfungi:YNL086W	intact:EBI-742756|uniprotkb:Q5XG83|uniprotkb:Q6NW33|uniprotkb:Q7L5M9|uniprotkb:Q96A53|uniprotkb:Q96FV1|uniprotkb:Q9BYF9|uniprotkb:Q9P1Y4|uniprotkb:B2R874|ensembl:ENSP00000355124	psi-mi:snapn_yeast(display_long)|uniprotkb:YNL086W(locus name)|uniprotkb:N2254(orf name)|uniprotkb:SNN1(gene name)|psi-mi:SNN1(display_short)|uniprotkb:SNAPIN-like protein 1(gene name synonym)	psi-mi:k1c19_human(display_long)|uniprotkb:Cytokeratin-19(gene name synonym)|uniprotkb:Keratin-19(gene name synonym)|uniprotkb:KRT19(gene name)|psi-mi:KRT19(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550152|imex:IM-24995-3109	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014313.1|sgd:S000005030|dip:DIP-1188N|mint:P48232|ensemblfungi:YNL086W(gene)|ensemblfungi:YNL086W_mRNA(transcript)|go:"GO:0005768"(endosome)|go:"GO:0007032"(endosome organization)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0032880"(regulation of protein localization)	refseq:NP_002267.2|ensembl:ENSG00000171345(gene)|ensembl:ENST00000361566(transcript)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0030018"(Z disc)|go:"GO:0042383"(sarcolemma)|go:"GO:0043034"(costamere)|go:"GO:0043627"(response to estrogen)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0060706"(cell differentiation involved in embryonic placenta development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071944"(cell periphery)|go:"GO:1990357"(terminal web)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR039008|mint:P08727|reactome:R-HSA-6805567|reactome:R-HSA-6809371|dip:DIP-35655N	-	crc64:33200D2F0F729DA1	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:XCPaHuGC9oKD/3W0gY5ZY8jKtFs559292	rogid:fqsG2nghpcmTtI39LiYVLNYuFIA9606	intact-crc:5DDD4837D7547A6E|rigid:CwltGDU4oRqebkTElyclVSZmLGU	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P48232	uniprotkb:P37198	intact:EBI-28775|uniprotkb:D6W193|ensemblfungi:YNL086W	intact:EBI-347978|intact:EBI-28983799|ensembl:ENSP00000305503|ensembl:ENSP00000407331|ensembl:ENSP00000471191|ensembl:ENSP00000473192|uniprotkb:Q6GTM2|uniprotkb:Q503A4|uniprotkb:Q96C43|uniprotkb:Q9NSL1|uniprotkb:B3KWU5	psi-mi:snapn_yeast(display_long)|uniprotkb:YNL086W(locus name)|uniprotkb:N2254(orf name)|uniprotkb:SNN1(gene name)|psi-mi:SNN1(display_short)|uniprotkb:SNAPIN-like protein 1(gene name synonym)	psi-mi:nup62_human(display_long)|uniprotkb:NUP62(gene name)|psi-mi:NUP62(display_short)|uniprotkb:62 kDa nucleoporin(gene name synonym)|uniprotkb:Nucleoporin Nup62(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550148|imex:IM-24995-3108	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014313.1|sgd:S000005030|dip:DIP-1188N|mint:P48232|ensemblfungi:YNL086W(gene)|ensemblfungi:YNL086W_mRNA(transcript)|go:"GO:0005768"(endosome)|go:"GO:0007032"(endosome organization)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0032880"(regulation of protein localization)	refseq:NP_714941.1|ensembl:ENSG00000213024(gene)|ensembl:ENST00000352066(transcript)|ensembl:ENST00000422090(transcript)|ensembl:ENST00000596217(transcript)|ensembl:ENST00000597029(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005642"(annulate lamellae)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007100"(mitotic centrosome separation)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007569"(cell aging)|go:"GO:0008219"(cell death)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0003682"(chromatin binding)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0019894"(kinesin binding)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042306"(regulation of protein import into nucleus)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043069"(negative regulation of programmed cell death)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045742"(positive regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046578"(regulation of Ras protein signal transduction)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0046601"(positive regulation of centriole replication)|go:"GO:0051028"(mRNA transport)|go:"GO:0051425"(PTB domain binding)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0072686"(mitotic spindle)|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|go:"GO:0090543"(Flemming body)|go:"GO:0098534"(centriole assembly)|go:"GO:1903438"(positive regulation of mitotic cytokinetic process)|go:"GO:1904781"(positive regulation of protein localization to centrosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR007758(Nucleoporin, Nsp1-like, C-terminal)|interpro:IPR026010|interpro:IPR033072|mint:P37198|rcsb pdb:2H4D|rcsb pdb:5IJN|rcsb pdb:5IJO|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|refseq:NP_714940.1|refseq:NP_001180286.1|refseq:NP_036478.2|refseq:NP_057637.2|ensembl:ENSP00000305503|ensembl:ENSP00000407331|ensembl:ENSP00000471191|ensembl:ENSP00000473192|dip:DIP-29749N	-	crc64:33200D2F0F729DA1	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:XCPaHuGC9oKD/3W0gY5ZY8jKtFs559292	rogid:v7mvKvTtVEnLMwcpUZIcdAzge009606	intact-crc:FB5CC5BC88C20943|rigid:rpFh96J0kfVyT0N8FIrOoIJ+kmM	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P48232	uniprotkb:P19012	intact:EBI-28775|uniprotkb:D6W193|ensemblfungi:YNL086W	intact:EBI-739566|uniprotkb:Q53XV8|uniprotkb:Q9BUG4|uniprotkb:B3KQY1|uniprotkb:B3KRA2|uniprotkb:E0CX14|ensembl:ENSP00000254043|ensembl:ENSP00000377546	psi-mi:snapn_yeast(display_long)|uniprotkb:YNL086W(locus name)|uniprotkb:N2254(orf name)|uniprotkb:SNN1(gene name)|psi-mi:SNN1(display_short)|uniprotkb:SNAPIN-like protein 1(gene name synonym)	psi-mi:k1c15_human(display_long)|uniprotkb:KRT15(gene name)|psi-mi:KRT15(display_short)|uniprotkb:KRTB(gene name synonym)|uniprotkb:Cytokeratin-15(gene name synonym)|uniprotkb:Keratin-15(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550144|imex:IM-24995-3107	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014313.1|sgd:S000005030|dip:DIP-1188N|mint:P48232|ensemblfungi:YNL086W(gene)|ensemblfungi:YNL086W_mRNA(transcript)|go:"GO:0005768"(endosome)|go:"GO:0007032"(endosome organization)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0032880"(regulation of protein localization)	refseq:NP_002266.2|ensembl:ENSG00000171346(gene)|ensembl:ENST00000254043(transcript)|ensembl:ENST00000393976(transcript)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0008544"(epidermis development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097110"(scaffold protein binding)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR039008|mint:P19012|reactome:R-HSA-6805567|reactome:R-HSA-6809371	-	crc64:33200D2F0F729DA1	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:XCPaHuGC9oKD/3W0gY5ZY8jKtFs559292	rogid:WrZQBYQvrWcfrR5ojWXrXp6spPE9606	intact-crc:C7ACB9D2AFD3B293|rigid:hL9Sjv5M1RtaCp4N61Zl1BEcb5g	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P19012	uniprotkb:P47121	intact:EBI-739566|uniprotkb:Q53XV8|uniprotkb:Q9BUG4|uniprotkb:B3KQY1|uniprotkb:B3KRA2|uniprotkb:E0CX14|ensembl:ENSP00000254043|ensembl:ENSP00000377546	intact:EBI-11532457|ensemblfungi:YJR071W	psi-mi:k1c15_human(display_long)|uniprotkb:KRT15(gene name)|psi-mi:KRT15(display_short)|uniprotkb:KRTB(gene name synonym)|uniprotkb:Cytokeratin-15(gene name synonym)|uniprotkb:Keratin-15(gene name synonym)	psi-mi:yj41_yeast(display_long)|uniprotkb:J1818(orf name)|uniprotkb:YJR071W(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550124|imex:IM-24995-3102	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002266.2|ensembl:ENSG00000171346(gene)|ensembl:ENST00000254043(transcript)|ensembl:ENST00000393976(transcript)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0008544"(epidermis development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097110"(scaffold protein binding)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR039008|mint:P19012|reactome:R-HSA-6805567|reactome:R-HSA-6809371	sgd:S000003832|ensemblfungi:YJR071W(gene)|ensemblfungi:YJR071W_mRNA(transcript)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/03/16	rogid:WrZQBYQvrWcfrR5ojWXrXp6spPE9606	rogid:5IM71Y0Z5uWfytzg3rXeNU+zCIs559292	intact-crc:7B91AE64D38B6FD2|rigid:N7wAs75Cz60FYATyk61zyKc9+i0	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O00444	uniprotkb:P47141	intact:EBI-746202|uniprotkb:Q8IYF0|uniprotkb:Q96Q95|uniprotkb:B2RAL0|uniprotkb:B7Z837|uniprotkb:B7Z8G7|uniprotkb:Q9UD84|uniprotkb:Q9UDE2|ensembl:ENSP00000270861	intact:EBI-25588|uniprotkb:D6VWS0|ensemblfungi:YJR101W	psi-mi:plk4_human(display_long)|uniprotkb:Polo-like kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase Sak(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 18(gene name synonym)|uniprotkb:PLK4(gene name)|psi-mi:PLK4(display_short)|uniprotkb:SAK(gene name synonym)|uniprotkb:STK18(gene name synonym)	psi-mi:rt26_yeast(display_long)|uniprotkb:RSM26(gene name)|psi-mi:RSM26(display_short)|uniprotkb:Mitochondrial small ribosomal subunit protein mS42(gene name synonym)|uniprotkb:J1952(orf name)|uniprotkb:YJR101W(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550136|imex:IM-24995-3105	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001177728.1|refseq:NP_001177730.1|refseq:NP_055079.3|dip:DIP-34467N|rcsb pdb:5LHZ|rcsb pdb:6N45|rcsb pdb:6N46|rcsb pdb:6W38|rcsb pdb:6W3I|rcsb pdb:6W3J|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|rcsb pdb:5LHY|reactome:R-HSA-5620912|reactome:R-HSA-8854518|ensembl:ENSG00000142731(gene)|ensembl:ENST00000270861(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0001741"(XY body)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007099"(centriole replication)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0046601"(positive regulation of centriole replication)|go:"GO:0060271"(cilium assembly)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0098535"(de novo centriole assembly involved in multi-ciliated epithelial cell differentiation)|go:"GO:0098536"(deuterosome)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033696|interpro:IPR033698|interpro:IPR033699|interpro:IPR033700|mint:O00444|rcsb pdb:2N19|rcsb pdb:3COK|rcsb pdb:4JXF|rcsb pdb:4N7V|rcsb pdb:4N7Z|rcsb pdb:4N9J|rcsb pdb:4YUR|rcsb pdb:4YYP	refseq:NP_012635.1|sgd:S000003862|mint:P47141|dip:DIP-6695N|ensemblfungi:YJR101W(gene)|ensemblfungi:YJR101W_mRNA(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0004784"(superoxide dismutase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0032543"(mitochondrial translation)|go:"GO:0046872"(metal ion binding)|interpro:IPR019832|interpro:IPR036314|interpro:IPR036324|rcsb pdb:5MRC|rcsb pdb:5MRE|rcsb pdb:5MRF	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:xqjVEnoGXDk/+2AzLRAkyPK80OI9606	rogid:SlIhesyBGcjVv9vDlv43gnSLZ2o559292	intact-crc:E06308168A5DB58B|rigid:YSl4RqDpH160BRgvgBss6G3F8xE	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P50222	uniprotkb:P47133	intact:EBI-748397|uniprotkb:O75263|ensembl:ENSP00000262041|uniprotkb:Q9UPL6|uniprotkb:B2R8I7|intact:EBI-10172134|intact:EBI-11522964|intact:EBI-11750003|intact:EBI-12702266|uniprotkb:A4D127	intact:EBI-25568|uniprotkb:D6VWQ6|uniprotkb:Q66R61|ensemblfungi:YJR088C	psi-mi:meox2_human(display_long)|uniprotkb:Mesenchyme homeobox 2(gene name synonym)|uniprotkb:Growth arrest-specific homeobox(gene name synonym)|uniprotkb:MEOX2(gene name)|psi-mi:MEOX2(display_short)|uniprotkb:GAX(gene name synonym)|uniprotkb:MOX2(gene name synonym)	psi-mi:emc2_yeast(display_long)|uniprotkb:EMC2(gene name)|psi-mi:EMC2(display_short)|uniprotkb:J1875(orf name)|uniprotkb:YJR088C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550132|imex:IM-24995-3104	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000106511(gene)|ensembl:ENST00000262041(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0001757"(somite specification)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007275"(multicellular organism development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008015"(blood circulation)|go:"GO:0016607"(nuclear speck)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060173"(limb development)|go:"GO:0061053"(somite development)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR042634|refseq:NP_005915.2	refseq:NP_012621.1|sgd:S000003848|dip:DIP-7609N|ensemblfungi:YJR088C(gene)|ensemblfungi:YJR088C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0072546"(EMC complex)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR039856|rcsb pdb:6WB9|rcsb pdb:7KRA|rcsb pdb:7KTX	-	-	crc64:157A03E75FB9E72A	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2017/05/26	rogid:fMv0ruKikzQ3MC0PBvJ3pOAjW+U9606	rogid:p1r7k3QtfCRO93w9iBzh6wYGL9Q559292	intact-crc:109BD4AD04AA45DD|rigid:Nl+LiBV9j9ECxZnmhoSaGE9xlXc	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P14136	uniprotkb:P47121	intact:EBI-744302|uniprotkb:Q53H98|uniprotkb:Q5D055|uniprotkb:Q6ZQS3|uniprotkb:Q7Z5J6|uniprotkb:Q7Z5J7|uniprotkb:Q96KS4|uniprotkb:Q96P18|uniprotkb:Q9UFD0|uniprotkb:B2RD44|uniprotkb:D3DX59|intact:EBI-3909365|uniprotkb:E9PAX3|ensembl:ENSP00000466598|uniprotkb:A7REI1	intact:EBI-11532457|ensemblfungi:YJR071W	psi-mi:gfap_human(display_long)|uniprotkb:GFAP(gene name)|psi-mi:GFAP(display_short)	psi-mi:yj41_yeast(display_long)|uniprotkb:J1818(orf name)|uniprotkb:YJR071W(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550128|imex:IM-24995-3103	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001124491.1|refseq:NP_001229305.1|refseq:NP_002046.1|ensembl:ENSG00000131095(gene)|ensembl:ENST00000588735(transcript)|go:"GO:0005178"(integrin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0009611"(response to wounding)|go:"GO:0010467"(gene expression)|go:"GO:0010625"(positive regulation of Schwann cell proliferation)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0014002"(astrocyte development)|go:"GO:0019900"(kinase binding)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0031102"(neuron projection regeneration)|go:"GO:0042802"(identical protein binding)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0044297"(cell body)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0051580"(regulation of neurotransmitter uptake)|go:"GO:0060020"(Bergmann glial cell differentiation)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0070779"(D-aspartate import across plasma membrane)|go:"GO:0097450"(astrocyte end-foot)|go:"GO:0098574"(cytoplasmic side of lysosomal membrane)|go:"GO:1904714"(regulation of chaperone-mediated autophagy)|interpro:IPR006821(Intermediate filament, DNA-binding region)|interpro:IPR018039|interpro:IPR027701|interpro:IPR039008|mint:P14136|rcsb pdb:6A9P|reactome:R-HSA-1251985|reactome:R-HSA-9613829	sgd:S000003832|ensemblfungi:YJR071W(gene)|ensemblfungi:YJR071W_mRNA(transcript)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/03/16	rogid:Pz4JW0WjMjBYILTDSX9jUmMqWhg9606	rogid:5IM71Y0Z5uWfytzg3rXeNU+zCIs559292	intact-crc:26B02D9558F5E8C2|rigid:sThOr4vPEYaMHtC3NM5RUYom1j8	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:A0A024R4Q5	uniprotkb:P47167	intact:EBI-11527449	intact:EBI-25691|uniprotkb:D6VWV3|ensemblfungi:YJR135C	psi-mi:a0a024r4q5_human(display_long)|uniprotkb:hCG_20946(orf name)|uniprotkb:TFPT(gene name)|psi-mi:TFPT(display_short)	psi-mi:cenpk_yeast(display_long)|uniprotkb:YJR135C(locus name)|uniprotkb:J2122(orf name)|uniprotkb:MCM22(gene name)|psi-mi:MCM22(display_short)|uniprotkb:Minichromosome maintenance protein 22(gene name synonym)|uniprotkb:CENP-K homolog(gene name synonym)|uniprotkb:Constitutive centromere-associated network protein MCM22(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550140|imex:IM-24995-3106	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_037474.1|interpro:IPR033555|go:"GO:0005654"(nucleoplasm)|go:"GO:0006915"(apoptotic process)	sgd:S000003896|refseq:NP_012669.1|mint:P47167|dip:DIP-1431N|ensemblfungi:YJR135C(gene)|ensemblfungi:YJR135C_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0007059"(chromosome segregation)|go:"GO:0034087"(establishment of mitotic sister chromatid cohesion)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|rcsb pdb:6OUA|rcsb pdb:6QLD|rcsb pdb:6QLE|rcsb pdb:6WUC|rcsb pdb:6YPC|rcsb pdb:7L7Q	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:juI/3gZemjc0hnXDJ9J+bIQ9pBw9606	rogid:LcYkK++8vfcxUaACTUgOFftDVyc559292	intact-crc:9BDF20795B10F942|rigid:ZTXIMsSGw1x74kumZO63mW+N3Co	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P48837	uniprotkb:P19012	intact:EBI-12324|ensemblfungi:YGR119C|uniprotkb:D6VUQ0	intact:EBI-739566|uniprotkb:Q53XV8|uniprotkb:Q9BUG4|uniprotkb:B3KQY1|uniprotkb:B3KRA2|uniprotkb:E0CX14|ensembl:ENSP00000254043|ensembl:ENSP00000377546	psi-mi:nup57_yeast(display_long)|uniprotkb:NUP57(gene name)|psi-mi:NUP57(display_short)|uniprotkb:YGR119C(locus name)|uniprotkb:G6320(orf name)|uniprotkb:Nuclear pore protein NUP57(gene name synonym)	psi-mi:k1c15_human(display_long)|uniprotkb:KRT15(gene name)|psi-mi:KRT15(display_short)|uniprotkb:KRTB(gene name synonym)|uniprotkb:Cytokeratin-15(gene name synonym)|uniprotkb:Keratin-15(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550196|imex:IM-24995-3120	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YGR119C(gene)|ensemblfungi:YGR119C_mRNA(transcript)|go:"GO:0005643"(nuclear pore)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036228"(protein localization to nuclear inner membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0051028"(mRNA transport)|interpro:IPR024864|interpro:IPR025574|interpro:IPR025712|refseq:NP_011634.1|sgd:S000003351|mint:P48837|dip:DIP-866N	refseq:NP_002266.2|ensembl:ENSG00000171346(gene)|ensembl:ENST00000254043(transcript)|ensembl:ENST00000393976(transcript)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0008544"(epidermis development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097110"(scaffold protein binding)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR039008|mint:P19012|reactome:R-HSA-6805567|reactome:R-HSA-6809371	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:ultDTflWHx7n/y2FrlWFf+lBKmw559292	rogid:WrZQBYQvrWcfrR5ojWXrXp6spPE9606	intact-crc:D2AF52E9D0E5C5C3|rigid:EWdg0xHy45l7+DZ8VcH2+fSyZqU	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P48837	uniprotkb:P43365	intact:EBI-12324|ensemblfungi:YGR119C|uniprotkb:D6VUQ0	intact:EBI-749530|uniprotkb:Q9NSD3|intact:EBI-10178394|uniprotkb:Q6FHH8|ensembl:ENSP00000350592|ensembl:ENSP00000377447|ensembl:ENSP00000377478	psi-mi:nup57_yeast(display_long)|uniprotkb:NUP57(gene name)|psi-mi:NUP57(display_short)|uniprotkb:YGR119C(locus name)|uniprotkb:G6320(orf name)|uniprotkb:Nuclear pore protein NUP57(gene name synonym)	psi-mi:magac_human(display_long)|uniprotkb:MAGE-12 antigen(gene name synonym)|uniprotkb:MAGE12F antigen(gene name synonym)|uniprotkb:Cancer/testis antigen 1.12(gene name synonym)|uniprotkb:MAGEA12(gene name)|psi-mi:MAGEA12(display_short)|uniprotkb:MAGE12(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550192|imex:IM-24995-3119	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YGR119C(gene)|ensemblfungi:YGR119C_mRNA(transcript)|go:"GO:0005643"(nuclear pore)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036228"(protein localization to nuclear inner membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0051028"(mRNA transport)|interpro:IPR024864|interpro:IPR025574|interpro:IPR025712|refseq:NP_011634.1|sgd:S000003351|mint:P48837|dip:DIP-866N	refseq:NP_001159858.1|refseq:NP_001159859.1|refseq:NP_005358.2|ensembl:ENSG00000213401(gene)|ensembl:ENST00000357916(transcript)|ensembl:ENST00000393869(transcript)|ensembl:ENST00000393900(transcript)|interpro:IPR002190(MAGE protein)|interpro:IPR021072|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:ultDTflWHx7n/y2FrlWFf+lBKmw559292	rogid:3/Jxz2VsFOb67RWqWj3xbTrw3s49606	intact-crc:A0080446BDE7307A|rigid:RsooH0U2Ig2+KcoPlyd4E/fjdww	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q08379	uniprotkb:P48837	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	intact:EBI-12324|ensemblfungi:YGR119C|uniprotkb:D6VUQ0	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:nup57_yeast(display_long)|uniprotkb:NUP57(gene name)|psi-mi:NUP57(display_short)|uniprotkb:YGR119C(locus name)|uniprotkb:G6320(orf name)|uniprotkb:Nuclear pore protein NUP57(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550188|imex:IM-24995-3118	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N	ensemblfungi:YGR119C(gene)|ensemblfungi:YGR119C_mRNA(transcript)|go:"GO:0005643"(nuclear pore)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036228"(protein localization to nuclear inner membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0051028"(mRNA transport)|interpro:IPR024864|interpro:IPR025574|interpro:IPR025712|refseq:NP_011634.1|sgd:S000003351|mint:P48837|dip:DIP-866N	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2017/05/26	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	rogid:ultDTflWHx7n/y2FrlWFf+lBKmw559292	intact-crc:4AA9A4C22F522C5C|rigid:lWusjqueKh0Hnk8R2KrjGBwfThU	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P48837	uniprotkb:Q7Z6G3-2	intact:EBI-12324|ensemblfungi:YGR119C|uniprotkb:D6VUQ0	intact:EBI-10172876|ensembl:ENSP00000457354|intact:EBI-14062040	psi-mi:nup57_yeast(display_long)|uniprotkb:NUP57(gene name)|psi-mi:NUP57(display_short)|uniprotkb:YGR119C(locus name)|uniprotkb:G6320(orf name)|uniprotkb:Nuclear pore protein NUP57(gene name synonym)	psi-mi:q7z6g3-2(display_long)|uniprotkb:EFCBP2(gene name synonym)|uniprotkb:Neuronal calcium-binding protein 2(gene name synonym)|uniprotkb:Synaptotagmin-interacting protein 2(gene name synonym)|uniprotkb:NECAB2(gene name)|psi-mi:NECAB2(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550184|imex:IM-24995-3117	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YGR119C(gene)|ensemblfungi:YGR119C_mRNA(transcript)|go:"GO:0005643"(nuclear pore)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036228"(protein localization to nuclear inner membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0051028"(mRNA transport)|interpro:IPR024864|interpro:IPR025574|interpro:IPR025712|refseq:NP_011634.1|sgd:S000003351|mint:P48837|dip:DIP-866N	ensembl:ENSG00000103154(gene)|ensembl:ENST00000565691(transcript)|uniprotkb:Q7Z6G3-2(isoform-parent)|intact:EBI-950070(isoform-parent)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:ultDTflWHx7n/y2FrlWFf+lBKmw559292	rogid:4S7oIx6h+mKzV3EPxqcfMNqaNko9606	intact-crc:35EB07DA5014C760|rigid:2L/mQtHxIaS+bEFnqSRPYF5iGLE	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P48837	uniprotkb:P13196	intact:EBI-12324|ensemblfungi:YGR119C|uniprotkb:D6VUQ0	intact:EBI-3905054|ensembl:ENSP00000309259|ensembl:ENSP00000378416|ensembl:ENSP00000417719|ensembl:ENSP00000418779	psi-mi:nup57_yeast(display_long)|uniprotkb:NUP57(gene name)|psi-mi:NUP57(display_short)|uniprotkb:YGR119C(locus name)|uniprotkb:G6320(orf name)|uniprotkb:Nuclear pore protein NUP57(gene name synonym)	psi-mi:hem1_human(display_long)|uniprotkb:ALAS1(gene name)|psi-mi:ALAS1(display_short)|uniprotkb:ALAS3(gene name synonym)|uniprotkb:ALASH(gene name synonym)|uniprotkb:5-aminolevulinic acid synthase 1(gene name synonym)|uniprotkb:Delta-ALA synthase 1(gene name synonym)|uniprotkb:Delta-aminolevulinate synthase 1(gene name synonym)|uniprotkb:OK/SW-cl.121(orf name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550180|imex:IM-24995-3116	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YGR119C(gene)|ensemblfungi:YGR119C_mRNA(transcript)|go:"GO:0005643"(nuclear pore)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036228"(protein localization to nuclear inner membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0051028"(mRNA transport)|interpro:IPR024864|interpro:IPR025574|interpro:IPR025712|refseq:NP_011634.1|sgd:S000003351|mint:P48837|dip:DIP-866N	refseq:NP_001291372.1|refseq:NP_001291373.1|refseq:NP_000679.1|refseq:NP_954635.1|go:"GO:0006783"(heme biosynthetic process)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0042541"(hemoglobin biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0048821"(erythrocyte development)|ensembl:ENSG00000023330(gene)|ensembl:ENST00000310271(transcript)|ensembl:ENST00000394965(transcript)|ensembl:ENST00000469224(transcript)|ensembl:ENST00000484952(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0003870"(5-aminolevulinate synthase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|interpro:IPR001917(Aminotransferase, class-II, pyridoxal-phosphate binding site)|interpro:IPR004839(Aminotransferase, class I and II)|interpro:IPR010961(Tetrapyrrole biosynthesis, 5-aminolevulinic acid synthase)|interpro:IPR015118(5-aminolevulinate synthase presequence)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|mint:P13196|reactome:R-HSA-189451|reactome:R-HSA-1989781|reactome:R-HSA-2151201|go:"GO:0006782"(protoporphyrinogen IX biosynthetic process)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:ultDTflWHx7n/y2FrlWFf+lBKmw559292	rogid:HFjJ6zrRF9UYD7LMB6A3CcxcS7c9606	intact-crc:54338C28162AAFC5|rigid:55dkBZdItqxpdefbuIni1NTAFrc	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O14641	uniprotkb:P48510	intact:EBI-740850|ensembl:ENSP00000005340|uniprotkb:Q53XM0|uniprotkb:D3DTN3	intact:EBI-6174|uniprotkb:D6W0A3|ensemblfungi:YMR276W	psi-mi:dvl2_human(display_long)|uniprotkb:DSH homolog 2(gene name synonym)|uniprotkb:DVL2(gene name)|psi-mi:DVL2(display_short)	psi-mi:dsk2_yeast(display_long)|uniprotkb:DSK2(gene name)|psi-mi:DSK2(display_short)|uniprotkb:SHE4(gene name synonym)|uniprotkb:YMR276W(locus name)|uniprotkb:YM8021.02(orf name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550156|imex:IM-24995-3110	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004413.1|ensembl:ENSG00000004975(gene)|ensembl:ENST00000005340(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005109"(frizzled binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0007507"(heart development)|go:"GO:0016235"(aggresome)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044340"(canonical Wnt signaling pathway involved in regulation of cell proliferation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0150012"(positive regulation of neuron projection arborization)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008341(Dishevelled-2 region)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:O14641|rcsb pdb:2REY|rcsb pdb:3CBX|rcsb pdb:3CBY|rcsb pdb:3CBZ|rcsb pdb:3CC0|rcsb pdb:4WIP|rcsb pdb:5LNP|rcsb pdb:5SUY|rcsb pdb:5SUZ|rcsb pdb:6IW3|rcsb pdb:6JCK|reactome:R-HSA-201681|reactome:R-HSA-201688|reactome:R-HSA-2028269|reactome:R-HSA-4086400|reactome:R-HSA-4608870|reactome:R-HSA-4641258|reactome:R-HSA-4641262|reactome:R-HSA-5099900|reactome:R-HSA-5368598|reactome:R-HSA-5663220|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9673324|ensembl:ENSP00000005340|dip:DIP-34433N	refseq:NP_014003.1|sgd:S000004889|dip:DIP-4398N|mint:P48510|ensemblfungi:YMR276W(gene)|ensemblfungi:YMR276W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030474"(spindle pole body duplication)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0072665"(protein localization to vacuole)|interpro:IPR000626(Ubiquitin)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR019954|interpro:IPR029071|rcsb pdb:1WR1|rcsb pdb:2BWB|rcsb pdb:2BWE|rcsb pdb:2BWF|rcsb pdb:3M63|rcsb pdb:4UN2|reactome:R-SCE-8856825	-	-	crc64:3F8691BB95E46569	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:2Vdc8oRnT4Mz/j+EXQXrL3AszOc9606	rogid:1hHbfo970BiDc/ZuAO8Jc6V9vEI559292	intact-crc:8574B6BA38725F91|rigid:OFBwQNwhklTLKJu+V2vrPLrktfw	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P40454	uniprotkb:P48775	intact:EBI-25278|uniprotkb:D6VVD4|ensemblfungi:YIL153W	intact:EBI-743494|ensembl:ENSP00000444788|ensembl:ENSP00000460086|uniprotkb:A8K053	psi-mi:ptpa1_yeast(display_long)|uniprotkb:YIL153W(locus name)|uniprotkb:RRD1(gene name)|psi-mi:RRD1(display_short)|uniprotkb:NCS1(gene name synonym)|uniprotkb:YPA1(gene name synonym)|uniprotkb:Peptidyl-prolyl cis-trans isomerase PTPA-1(gene name synonym)|uniprotkb:Phosphotyrosyl phosphatase activator 1(gene name synonym)	psi-mi:t23o_human(display_long)|uniprotkb:Tryptophan pyrrolase(gene name synonym)|uniprotkb:Tryptophan oxygenase(gene name synonym)|uniprotkb:Tryptamin 2,3-dioxygenase(gene name synonym)|uniprotkb:TDO2(gene name)|psi-mi:TDO2(display_short)|uniprotkb:TDO(gene name synonym)|uniprotkb:Tryptophanase(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550172|imex:IM-24995-3114	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012113.1|sgd:S000001415|mint:P40454|dip:DIP-5663N|ensemblfungi:YIL153W(gene)|ensemblfungi:YIL153W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006914"(autophagy)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008160"(protein tyrosine phosphatase activator activity)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0043618"(regulation of transcription from RNA polymerase II promoter in response to stress)|interpro:IPR004327(Phosphotyrosyl phosphatase activator, PTPA)|interpro:IPR037218|interpro:IPR043170|rcsb pdb:2IXO|rcsb pdb:2IXP	ensembl:ENSG00000151790(gene)|ensembl:ENSG00000262635(gene)|ensembl:ENST00000536354(transcript)|ensembl:ENST00000573403(transcript)|go:"GO:0004833"(tryptophan 2,3-dioxygenase activity)|go:"GO:0005829"(cytosol)|go:"GO:0016597"(amino acid binding)|go:"GO:0019441"(tryptophan catabolic process to kynurenine)|go:"GO:0019442"(tryptophan catabolic process to acetyl-CoA)|go:"GO:0019825"(oxygen binding)|go:"GO:0020037"(heme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051289"(protein homotetramerization)|go:"GO:1904842"(response to nitroglycerin)|interpro:IPR004981(Tryptophan 2,3-dioxygenase)|interpro:IPR037217|mint:P48775|rcsb pdb:4PW8|rcsb pdb:5TI9|rcsb pdb:5TIA|rcsb pdb:6A4I|rcsb pdb:6PYY|rcsb pdb:6PYZ|rcsb pdb:6UD5|rcsb pdb:6VBN|reactome:R-HSA-71240|refseq:NP_005642.1	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:It2q8WlpmvLEZ1fqpRF5Fypw9Q4559292	rogid:S+cyc710I52nIFQWgKhXFul9QZw9606	intact-crc:22464FEEBCC8E2C9|rigid:t7CR6F0wQMIWVXG7RAozbNhJ+N0	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P48775	uniprotkb:P32502	intact:EBI-743494|ensembl:ENSP00000444788|ensembl:ENSP00000460086|uniprotkb:A8K053	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:t23o_human(display_long)|uniprotkb:Tryptophan pyrrolase(gene name synonym)|uniprotkb:Tryptophan oxygenase(gene name synonym)|uniprotkb:Tryptamin 2,3-dioxygenase(gene name synonym)|uniprotkb:TDO2(gene name)|psi-mi:TDO2(display_short)|uniprotkb:TDO(gene name synonym)|uniprotkb:Tryptophanase(gene name synonym)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550168|imex:IM-24995-3113	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000151790(gene)|ensembl:ENSG00000262635(gene)|ensembl:ENST00000536354(transcript)|ensembl:ENST00000573403(transcript)|go:"GO:0004833"(tryptophan 2,3-dioxygenase activity)|go:"GO:0005829"(cytosol)|go:"GO:0016597"(amino acid binding)|go:"GO:0019441"(tryptophan catabolic process to kynurenine)|go:"GO:0019442"(tryptophan catabolic process to acetyl-CoA)|go:"GO:0019825"(oxygen binding)|go:"GO:0020037"(heme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051289"(protein homotetramerization)|go:"GO:1904842"(response to nitroglycerin)|interpro:IPR004981(Tryptophan 2,3-dioxygenase)|interpro:IPR037217|mint:P48775|rcsb pdb:4PW8|rcsb pdb:5TI9|rcsb pdb:5TIA|rcsb pdb:6A4I|rcsb pdb:6PYY|rcsb pdb:6PYZ|rcsb pdb:6UD5|rcsb pdb:6VBN|reactome:R-HSA-71240|refseq:NP_005642.1	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731	-	-	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:S+cyc710I52nIFQWgKhXFul9QZw9606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:93531C3BFAFD31E5|rigid:ppffcJhnWTZPhNOu91xniZ0FcvE	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P38340	uniprotkb:P48775	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-743494|ensembl:ENSP00000444788|ensembl:ENSP00000460086|uniprotkb:A8K053	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:t23o_human(display_long)|uniprotkb:Tryptophan pyrrolase(gene name synonym)|uniprotkb:Tryptophan oxygenase(gene name synonym)|uniprotkb:Tryptamin 2,3-dioxygenase(gene name synonym)|uniprotkb:TDO2(gene name)|psi-mi:TDO2(display_short)|uniprotkb:TDO(gene name synonym)|uniprotkb:Tryptophanase(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550164|imex:IM-24995-3112	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F	ensembl:ENSG00000151790(gene)|ensembl:ENSG00000262635(gene)|ensembl:ENST00000536354(transcript)|ensembl:ENST00000573403(transcript)|go:"GO:0004833"(tryptophan 2,3-dioxygenase activity)|go:"GO:0005829"(cytosol)|go:"GO:0016597"(amino acid binding)|go:"GO:0019441"(tryptophan catabolic process to kynurenine)|go:"GO:0019442"(tryptophan catabolic process to acetyl-CoA)|go:"GO:0019825"(oxygen binding)|go:"GO:0020037"(heme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051289"(protein homotetramerization)|go:"GO:1904842"(response to nitroglycerin)|interpro:IPR004981(Tryptophan 2,3-dioxygenase)|interpro:IPR037217|mint:P48775|rcsb pdb:4PW8|rcsb pdb:5TI9|rcsb pdb:5TIA|rcsb pdb:6A4I|rcsb pdb:6PYY|rcsb pdb:6PYZ|rcsb pdb:6UD5|rcsb pdb:6VBN|reactome:R-HSA-71240|refseq:NP_005642.1	-	crc64:66699F37B0013088	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:S+cyc710I52nIFQWgKhXFul9QZw9606	intact-crc:796D1616D202E5BD|rigid:0jJMO8ij0i4soToT9UC7lpFwQVI	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P32610	uniprotkb:P48775	intact:EBI-20264|uniprotkb:D3DLJ9|ensemblfungi:YEL051W	intact:EBI-743494|ensembl:ENSP00000444788|ensembl:ENSP00000460086|uniprotkb:A8K053	psi-mi:vatd_yeast(display_long)|uniprotkb:VMA8(gene name)|psi-mi:VMA8(display_short)|uniprotkb:YEL051W(locus name)|uniprotkb:SYGP-ORF11(orf name)|uniprotkb:Vacuolar proton pump subunit D(gene name synonym)	psi-mi:t23o_human(display_long)|uniprotkb:Tryptophan pyrrolase(gene name synonym)|uniprotkb:Tryptophan oxygenase(gene name synonym)|uniprotkb:Tryptamin 2,3-dioxygenase(gene name synonym)|uniprotkb:TDO2(gene name)|psi-mi:TDO2(display_short)|uniprotkb:TDO(gene name synonym)|uniprotkb:Tryptophanase(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550160|imex:IM-24995-3111	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010863.1|sgd:S000000777|ensemblfungi:YEL051W(gene)|ensemblfungi:YEL051W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0016471"(vacuolar proton-transporting V-type ATPase complex)|go:"GO:0033176"(proton-transporting V-type ATPase complex)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR002699(ATPase, V1/A1 complex, subunit D)|rcsb pdb:3J9T|rcsb pdb:3J9U|rcsb pdb:3J9V|rcsb pdb:4RND|rcsb pdb:5BW9|rcsb pdb:5D80|rcsb pdb:5VOX|rcsb pdb:5VOY|rcsb pdb:5VOZ|rcsb pdb:6O7V|rcsb pdb:6O7W|rcsb pdb:6O7X|reactome:R-SCE-1222556|reactome:R-SCE-6798695|reactome:R-SCE-77387|reactome:R-SCE-917977|reactome:R-SCE-9639288|dip:DIP-2959N|mint:P32610	ensembl:ENSG00000151790(gene)|ensembl:ENSG00000262635(gene)|ensembl:ENST00000536354(transcript)|ensembl:ENST00000573403(transcript)|go:"GO:0004833"(tryptophan 2,3-dioxygenase activity)|go:"GO:0005829"(cytosol)|go:"GO:0016597"(amino acid binding)|go:"GO:0019441"(tryptophan catabolic process to kynurenine)|go:"GO:0019442"(tryptophan catabolic process to acetyl-CoA)|go:"GO:0019825"(oxygen binding)|go:"GO:0020037"(heme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051289"(protein homotetramerization)|go:"GO:1904842"(response to nitroglycerin)|interpro:IPR004981(Tryptophan 2,3-dioxygenase)|interpro:IPR037217|mint:P48775|rcsb pdb:4PW8|rcsb pdb:5TI9|rcsb pdb:5TIA|rcsb pdb:6A4I|rcsb pdb:6PYY|rcsb pdb:6PYZ|rcsb pdb:6UD5|rcsb pdb:6VBN|reactome:R-HSA-71240|refseq:NP_005642.1	-	crc64:FDE93E1FAF0AEC5B	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:rrwRno7lCnDeTNwawONkGwV8Hkg559292	rogid:S+cyc710I52nIFQWgKhXFul9QZw9606	intact-crc:931B2AA92464A7F7|rigid:k/4RXew9tqL8bMsUlj6jyHMJQ30	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P40482	uniprotkb:P48775	intact:EBI-16592|ensemblfungi:YIL109C|uniprotkb:D6VVH8	intact:EBI-743494|ensembl:ENSP00000444788|ensembl:ENSP00000460086|uniprotkb:A8K053	psi-mi:sec24_yeast(display_long)|uniprotkb:SEC24(gene name)|psi-mi:SEC24(display_short)|uniprotkb:Abnormal nuclear morphology 1(gene name synonym)|uniprotkb:ANU1(gene name synonym)|uniprotkb:YIL109C(locus name)	psi-mi:t23o_human(display_long)|uniprotkb:Tryptophan pyrrolase(gene name synonym)|uniprotkb:Tryptophan oxygenase(gene name synonym)|uniprotkb:Tryptamin 2,3-dioxygenase(gene name synonym)|uniprotkb:TDO2(gene name)|psi-mi:TDO2(display_short)|uniprotkb:TDO(gene name synonym)|uniprotkb:Tryptophanase(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550176|imex:IM-24995-3115	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012157.3|ensemblfungi:YIL109C(gene)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016236"(macroautophagy)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0070971"(endoplasmic reticulum exit site)|ensemblfungi:YIL109C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0090110"(COPII-coated vesicle cargo loading)|interpro:IPR006895(Zinc finger, Sec23/Sec24-type)|interpro:IPR006896(Sec23/Sec24 trunk region)|interpro:IPR006900(Sec23/Sec24 helical region)|interpro:IPR007123(Gelsolin region)|interpro:IPR012990(Sec23/Sec24 beta-sandwich)|interpro:IPR029006|interpro:IPR036174|interpro:IPR036175|interpro:IPR036180|go:"GO:0000149"(SNARE binding)|go:"GO:0000329"(fungal-type vacuole membrane)|interpro:IPR036465|interpro:IPR041742|rcsb pdb:1M2V|rcsb pdb:1PCX|rcsb pdb:1PD0|rcsb pdb:1PD1|rcsb pdb:4BZI|rcsb pdb:6GNI|rcsb pdb:6ZGA|reactome:R-SCE-204005|reactome:R-SCE-5694530|reactome:R-SCE-983170|go:"GO:0005048"(signal sequence binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|sgd:S000001371|dip:DIP-2233N|mint:P40482	ensembl:ENSG00000151790(gene)|ensembl:ENSG00000262635(gene)|ensembl:ENST00000536354(transcript)|ensembl:ENST00000573403(transcript)|go:"GO:0004833"(tryptophan 2,3-dioxygenase activity)|go:"GO:0005829"(cytosol)|go:"GO:0016597"(amino acid binding)|go:"GO:0019441"(tryptophan catabolic process to kynurenine)|go:"GO:0019442"(tryptophan catabolic process to acetyl-CoA)|go:"GO:0019825"(oxygen binding)|go:"GO:0020037"(heme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051289"(protein homotetramerization)|go:"GO:1904842"(response to nitroglycerin)|interpro:IPR004981(Tryptophan 2,3-dioxygenase)|interpro:IPR037217|mint:P48775|rcsb pdb:4PW8|rcsb pdb:5TI9|rcsb pdb:5TIA|rcsb pdb:6A4I|rcsb pdb:6PYY|rcsb pdb:6PYZ|rcsb pdb:6UD5|rcsb pdb:6VBN|reactome:R-HSA-71240|refseq:NP_005642.1	-	crc64:35E2BDD24CC75899	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:e7ekVFzZJMZvfRUZ9Q2jDQ/hvs0559292	rogid:S+cyc710I52nIFQWgKhXFul9QZw9606	intact-crc:3D83C7C874E5E11B|rigid:e1ekJe+ubt+dKlyu1GO5jSgwoVw	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P51116	uniprotkb:P29461	intact:EBI-740459|uniprotkb:Q8WUM2|uniprotkb:Q86V09|uniprotkb:B2R9M2|uniprotkb:D3DTQ1|ensembl:ENSP00000250113	intact:EBI-14188|ensemblfungi:YOR208W|uniprotkb:D6W2R4	psi-mi:fxr2_human(display_long)|uniprotkb:FXR2(gene name)|psi-mi:FXR2(display_short)|uniprotkb:FMR1L2(gene name synonym)	psi-mi:ptp2_yeast(display_long)|uniprotkb:Protein-tyrosine phosphatase 2(gene name synonym)|uniprotkb:PTP2(gene name)|psi-mi:PTP2(display_short)|uniprotkb:YOR208W(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550232|imex:IM-24995-3129	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR004087(K Homology)|refseq:NP_004851.2|ensembl:ENSG00000129245(gene)|ensembl:ENST00000250113(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0044326"(dendritic spine neck)|go:"GO:0045182"(translation regulator activity)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0098793"(presynapse)|go:"GO:1902737"(dendritic filopodium)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|interpro:IPR004088(K Homology, type 1)|interpro:IPR008395(Agenet)|interpro:IPR022034|interpro:IPR032172|interpro:IPR036612|interpro:IPR040148|interpro:IPR040472|interpro:IPR041560|mint:P51116|rcsb pdb:3H8Z	sgd:S000005734|ensemblfungi:YOR208W(gene)|ensemblfungi:YOR208W_mRNA(transcript)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0043937"(regulation of sporulation)|go:"GO:0051457"(maintenance of protein location in nucleus)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|refseq:NP_014851.3|dip:DIP-2369N	-	-	crc64:1033D2F0AA23BD35	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:NnYgyzD2NRGIO1ZHukr5qy44qRE9606	rogid:y6lL7sE5o4uuIJ2YtaKCUzxz8o0559292	intact-crc:224A1D49154A7944|rigid:B5gDZeiWjPzPEo5bLYrloAF5b10	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P51116	uniprotkb:P32354	intact:EBI-740459|uniprotkb:Q8WUM2|uniprotkb:Q86V09|uniprotkb:B2R9M2|uniprotkb:D3DTQ1|ensembl:ENSP00000250113	intact:EBI-5965|uniprotkb:D6VVD7|ensemblfungi:YIL150C	psi-mi:fxr2_human(display_long)|uniprotkb:FXR2(gene name)|psi-mi:FXR2(display_short)|uniprotkb:FMR1L2(gene name synonym)	psi-mi:mcm10_yeast(display_long)|uniprotkb:YIL150C(locus name)|uniprotkb:MCM10(gene name)|psi-mi:MCM10(display_short)|uniprotkb:DNA43(gene name synonym)|uniprotkb:Protein DNA43(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550228|imex:IM-24995-3128	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR004087(K Homology)|refseq:NP_004851.2|ensembl:ENSG00000129245(gene)|ensembl:ENST00000250113(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0044326"(dendritic spine neck)|go:"GO:0045182"(translation regulator activity)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0098793"(presynapse)|go:"GO:1902737"(dendritic filopodium)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|interpro:IPR004088(K Homology, type 1)|interpro:IPR008395(Agenet)|interpro:IPR022034|interpro:IPR032172|interpro:IPR036612|interpro:IPR040148|interpro:IPR040472|interpro:IPR041560|mint:P51116|rcsb pdb:3H8Z	refseq:NP_012116.1|sgd:S000001412|dip:DIP-1293N|mint:P32354|ensemblfungi:YIL150C(gene)|ensemblfungi:YIL150C_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005657"(replication fork)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006348"|go:"GO:0007049"(cell cycle)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0046872"(metal ion binding)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR015408(Zinc finger, Mcm10/DnaG-type)|interpro:IPR040184|reactome:R-SCE-68962	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:NnYgyzD2NRGIO1ZHukr5qy44qRE9606	rogid:D2K/tLON/CnIcTTqkAQOdTZrRlg559292	intact-crc:366E9052D6406486|rigid:+bhE3w6I1kpJayBmaB4tg0UDEQ0	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P51116	intact:EBI-11522220	intact:EBI-740459|uniprotkb:Q8WUM2|uniprotkb:Q86V09|uniprotkb:B2R9M2|uniprotkb:D3DTQ1|ensembl:ENSP00000250113	-	psi-mi:fxr2_human(display_long)|uniprotkb:FXR2(gene name)|psi-mi:FXR2(display_short)|uniprotkb:FMR1L2(gene name synonym)	psi-mi:lsb3(display_short)|psi-mi:EBI-11522220(display_long)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550224|imex:IM-24995-3127	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR004087(K Homology)|refseq:NP_004851.2|ensembl:ENSG00000129245(gene)|ensembl:ENST00000250113(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0044326"(dendritic spine neck)|go:"GO:0045182"(translation regulator activity)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0098793"(presynapse)|go:"GO:1902737"(dendritic filopodium)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|interpro:IPR004088(K Homology, type 1)|interpro:IPR008395(Agenet)|interpro:IPR022034|interpro:IPR032172|interpro:IPR036612|interpro:IPR040148|interpro:IPR040472|interpro:IPR041560|mint:P51116|rcsb pdb:3H8Z	-	-	-	no-uniprot-update:	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:NnYgyzD2NRGIO1ZHukr5qy44qRE9606	rogid:lsGJZWImagMoiiCZztCcxCn2LlU4932	intact-crc:2CB82423F56342BB|rigid:Ip2hgPhCGE2zPYgJQ9/bnSugGCk	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P39984	uniprotkb:P49910	intact:EBI-8185|uniprotkb:D3DLJ4|ensemblfungi:YEL056W	intact:EBI-741694|intact:EBI-28968591|ensembl:ENSP00000366542|ensembl:ENSP00000507525	psi-mi:hat2_yeast(display_long)|uniprotkb:HAT2(gene name)|psi-mi:HAT2(display_short)|uniprotkb:YEL056W(locus name)	psi-mi:zn165_human(display_long)|uniprotkb:LD65(gene name synonym)|uniprotkb:Zinc finger and SCAN domain-containing protein 7(gene name synonym)|uniprotkb:Cancer/testis antigen 53(gene name synonym)|uniprotkb:ZNF165(gene name)|psi-mi:ZNF165(display_short)|uniprotkb:ZPF165(gene name synonym)|uniprotkb:ZSCAN7(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550220|imex:IM-24995-3126	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000000782|refseq:NP_010858.3|mint:P39984|dip:DIP-2363N|ensemblfungi:YEL056W(gene)|ensemblfungi:YEL056W_mRNA(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006333"(chromatin assembly or disassembly)|go:"GO:0006348"|go:"GO:0016573"(histone acetylation)|go:"GO:0042393"(histone binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR022052|interpro:IPR036322|rcsb pdb:4PSW|rcsb pdb:4PSX|reactome:R-SCE-3214815|reactome:R-SCE-3214847|reactome:R-SCE-3214858	refseq:NP_003438.1|ensembl:ENSP00000366542|ensembl:ENSP00000507525|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR038269|mint:P49910|ensembl:ENSG00000197279(gene)|ensembl:ENST00000377325(transcript)|ensembl:ENST00000683778(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|refseq:XP_016866747.1|refseq:XP_016866748.1|refseq:XP_016866749.1	-	crc64:C27A91C99D9FCAB7	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:WlhnJ6TT8FLgKn4ZtoJh0tWUBQk559292	rogid:4BpNwyrtFulW7rWXuy+Y7cdgYps9606	intact-crc:9A2F30E303C1BECA|rigid:0LRXkxK0Tebwqa2us2WlyR13F1Q	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P37198	uniprotkb:P48837	intact:EBI-347978|intact:EBI-28983799|ensembl:ENSP00000305503|ensembl:ENSP00000407331|ensembl:ENSP00000471191|ensembl:ENSP00000473192|uniprotkb:Q6GTM2|uniprotkb:Q503A4|uniprotkb:Q96C43|uniprotkb:Q9NSL1|uniprotkb:B3KWU5	intact:EBI-12324|ensemblfungi:YGR119C|uniprotkb:D6VUQ0	psi-mi:nup62_human(display_long)|uniprotkb:NUP62(gene name)|psi-mi:NUP62(display_short)|uniprotkb:62 kDa nucleoporin(gene name synonym)|uniprotkb:Nucleoporin Nup62(gene name synonym)	psi-mi:nup57_yeast(display_long)|uniprotkb:NUP57(gene name)|psi-mi:NUP57(display_short)|uniprotkb:YGR119C(locus name)|uniprotkb:G6320(orf name)|uniprotkb:Nuclear pore protein NUP57(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550200|imex:IM-24995-3121	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_714941.1|ensembl:ENSG00000213024(gene)|ensembl:ENST00000352066(transcript)|ensembl:ENST00000422090(transcript)|ensembl:ENST00000596217(transcript)|ensembl:ENST00000597029(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005642"(annulate lamellae)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007100"(mitotic centrosome separation)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007569"(cell aging)|go:"GO:0008219"(cell death)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0003682"(chromatin binding)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0019894"(kinesin binding)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042306"(regulation of protein import into nucleus)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043069"(negative regulation of programmed cell death)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045742"(positive regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046578"(regulation of Ras protein signal transduction)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0046601"(positive regulation of centriole replication)|go:"GO:0051028"(mRNA transport)|go:"GO:0051425"(PTB domain binding)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0072686"(mitotic spindle)|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|go:"GO:0090543"(Flemming body)|go:"GO:0098534"(centriole assembly)|go:"GO:1903438"(positive regulation of mitotic cytokinetic process)|go:"GO:1904781"(positive regulation of protein localization to centrosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR007758(Nucleoporin, Nsp1-like, C-terminal)|interpro:IPR026010|interpro:IPR033072|mint:P37198|rcsb pdb:2H4D|rcsb pdb:5IJN|rcsb pdb:5IJO|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|refseq:NP_714940.1|refseq:NP_001180286.1|refseq:NP_036478.2|refseq:NP_057637.2|ensembl:ENSP00000305503|ensembl:ENSP00000407331|ensembl:ENSP00000471191|ensembl:ENSP00000473192|dip:DIP-29749N	ensemblfungi:YGR119C(gene)|ensemblfungi:YGR119C_mRNA(transcript)|go:"GO:0005643"(nuclear pore)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036228"(protein localization to nuclear inner membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0051028"(mRNA transport)|interpro:IPR024864|interpro:IPR025574|interpro:IPR025712|refseq:NP_011634.1|sgd:S000003351|mint:P48837|dip:DIP-866N	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:v7mvKvTtVEnLMwcpUZIcdAzge009606	rogid:ultDTflWHx7n/y2FrlWFf+lBKmw559292	intact-crc:AA9D51CF7C0D3F92|rigid:VKD44/kn1QgtmQW8jZJ27AtTQoA	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P32502	uniprotkb:P49247	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	intact:EBI-744831|uniprotkb:Q541P9|uniprotkb:Q96BJ6|ensembl:ENSP00000283646	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:rpia_human(display_long)|uniprotkb:Phosphoriboisomerase(gene name synonym)|uniprotkb:RPIA(gene name)|psi-mi:RPIA(display_short)|uniprotkb:RPI(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550212|imex:IM-24995-3124	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731	refseq:NP_653164.2|ensembl:ENSG00000153574(gene)|ensembl:ENST00000283646(transcript)|go:"GO:0004751"(ribose-5-phosphate isomerase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006014"(D-ribose metabolic process)|go:"GO:0006098"(pentose-phosphate shunt)|go:"GO:0009052"(pentose-phosphate shunt, non-oxidative branch)|go:"GO:0019693"(ribose phosphate metabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048029"(monosaccharide binding)|interpro:IPR004788(Ribose 5-phosphate isomerase)|interpro:IPR020672|interpro:IPR037171|mint:P49247|reactome:R-HSA-5659996|reactome:R-HSA-6791461|reactome:R-HSA-71336	-	crc64:A5409FAF1594854C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	rogid:gddu0Xp/dx4JwbFMs50pQCvvbws9606	intact-crc:AB54154448090B7E|rigid:FIQgDE5w8ZRTYm40k7VpBlc0dhA	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P49247	uniprotkb:P38340	intact:EBI-744831|uniprotkb:Q541P9|uniprotkb:Q96BJ6|ensembl:ENSP00000283646	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:rpia_human(display_long)|uniprotkb:Phosphoriboisomerase(gene name synonym)|uniprotkb:RPIA(gene name)|psi-mi:RPIA(display_short)|uniprotkb:RPI(gene name synonym)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550208|imex:IM-24995-3123	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_653164.2|ensembl:ENSG00000153574(gene)|ensembl:ENST00000283646(transcript)|go:"GO:0004751"(ribose-5-phosphate isomerase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006014"(D-ribose metabolic process)|go:"GO:0006098"(pentose-phosphate shunt)|go:"GO:0009052"(pentose-phosphate shunt, non-oxidative branch)|go:"GO:0019693"(ribose phosphate metabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048029"(monosaccharide binding)|interpro:IPR004788(Ribose 5-phosphate isomerase)|interpro:IPR020672|interpro:IPR037171|mint:P49247|reactome:R-HSA-5659996|reactome:R-HSA-6791461|reactome:R-HSA-71336	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F	-	-	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:gddu0Xp/dx4JwbFMs50pQCvvbws9606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:5B4A077BBA7243CF|rigid:N5V4GvqknWvyrUhzlVV65DEhyfw	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P26641	uniprotkb:P49090	intact:EBI-351467|uniprotkb:Q6PJ62|uniprotkb:Q6PK31|uniprotkb:Q96CU2|uniprotkb:Q9P196|intact:EBI-2321928|uniprotkb:B4DTG2|ensembl:ENSP00000331901	intact:EBI-3048|uniprotkb:E9P8Y0|uniprotkb:D6VUQ6|ensemblfungi:YGR124W	psi-mi:ef1g_human(display_long)|uniprotkb:PRO1608(orf name)|uniprotkb:EEF1G(gene name)|psi-mi:EEF1G(display_short)|uniprotkb:EF1G(gene name synonym)|uniprotkb:eEF-1B gamma(gene name synonym)	psi-mi:asns2_yeast(display_long)|uniprotkb:ASN2(gene name)|psi-mi:ASN2(display_short)|uniprotkb:YGR124W(locus name)|uniprotkb:G6358(orf name)|uniprotkb:Glutamine-dependent asparagine synthetase 2(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550204|imex:IM-24995-3122	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001395.1|ensembl:ENSG00000254772(gene)|ensembl:ENST00000329251(transcript)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006414"(translational elongation)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001662(Translation elongation factor EF1B, gamma chain, conserved)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR036249|interpro:IPR036282|interpro:IPR036433|interpro:IPR040079|mint:P26641|rcsb pdb:1PBU|rcsb pdb:5DQS|rcsb pdb:5JPO|reactome:R-HSA-156842|dip:DIP-32516N	refseq:NP_011640.1|sgd:S000003356|dip:DIP-5189N|mint:P49090|ensemblfungi:YGR124W(gene)|ensemblfungi:YGR124W_mRNA(transcript)|go:"GO:0004066"("asparagine synthase (glutamine-hydrolyzing) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006529"(asparagine biosynthetic process)|go:"GO:0006541"(glutamine metabolic process)|go:"GO:0070981"(L-asparagine biosynthetic process)|interpro:IPR001962(Asparagine synthase)|interpro:IPR006426(Asparagine synthase, glutamine-hydrolyzing)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR017932|interpro:IPR029055|interpro:IPR033738|reactome:R-SCE-8963693	-	-	crc64:2809F3F0FEDE4183	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:biVN96umeEdPm/wvPN4VwbSRHTs9606	rogid:h8FNSX14kWwOuKbbuLZsdxrqaXU559292	intact-crc:C657FDC7BF158092|rigid:K8jmAk945MRBrNKC+V+zagQ14uU	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P39518	uniprotkb:P49902	intact:EBI-10082|uniprotkb:D3DLR3|ensemblfungi:YER015W	intact:EBI-742084|uniprotkb:Q5JUV5|uniprotkb:D3DR91|ensembl:ENSP00000339479|ensembl:ENSP00000383960|ensembl:ENSP00000501689|ensembl:ENSP00000502205|ensembl:ENSP00000502679|ensembl:ENSP00000502801|uniprotkb:B7Z382	psi-mi:lcf2_yeast(display_long)|uniprotkb:YER015W(locus name)|uniprotkb:FAA2(gene name)|psi-mi:FAA2(display_short)|uniprotkb:FAM1(gene name synonym)|uniprotkb:Long-chain acyl-CoA synthetase 2(gene name synonym)|uniprotkb:Fatty acid activator 2(gene name synonym)	psi-mi:5ntc_human(display_long)|uniprotkb:Cytosolic 5'-nucleotidase II(gene name synonym)|uniprotkb:NT5C2(gene name)|psi-mi:NT5C2(display_short)|uniprotkb:NT5B(gene name synonym)|uniprotkb:NT5CP(gene name synonym)|uniprotkb:PNT5(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550216|imex:IM-24995-3125	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000000817|ensemblfungi:YER015W_mRNA(transcript)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0004467"(long-chain fatty acid-CoA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0015910"(long-chain fatty acid import into peroxisome)|go:"GO:0015916"(fatty-acyl-CoA transport)|go:"GO:0016020"(membrane)|go:"GO:0031956"(medium-chain fatty acid-CoA ligase activity)|go:"GO:0031957"(very long-chain fatty acid-CoA ligase activity)|go:"GO:0042760"(very long-chain fatty acid catabolic process)|go:"GO:0102391"(decanoate-CoA ligase activity)|ensemblfungi:YER015W(gene)|interpro:IPR020845|interpro:IPR000873(AMP-dependent synthetase and ligase)|reactome:R-SCE-75876|refseq:NP_010931.3|dip:DIP-6565N	ensembl:ENST00000675326(transcript)|refseq:NP_001127845.1|refseq:NP_036361.1|ensembl:ENSG00000076685(gene)|ensembl:ENST00000343289(transcript)|ensembl:ENST00000404739(transcript)|ensembl:ENST00000674696(transcript)|ensembl:ENST00000676449(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0005829"(cytosol)|go:"GO:0006204"(IMP catabolic process)|go:"GO:0008253"(5'-nucleotidase activity)|go:"GO:0019428"(allantoin biosynthetic process)|go:"GO:0046040"(IMP metabolic process)|go:"GO:0046085"(adenosine metabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0050483"(IMP 5'-nucleotidase activity)|interpro:IPR008380(HAD-superfamily hydrolase, subfamily IG, 5'-nucleotidase)|interpro:IPR016695(Purine 5'-nucleotidase)|interpro:IPR023214|interpro:IPR036412|mint:P49902|rcsb pdb:2J2C|rcsb pdb:2JC9|rcsb pdb:2JCM|rcsb pdb:2XCV|rcsb pdb:2XCW|rcsb pdb:2XCX|rcsb pdb:2XJB|rcsb pdb:2XJC|rcsb pdb:2XJD|rcsb pdb:2XJE|rcsb pdb:2XJF|rcsb pdb:4H4B|rcsb pdb:5CQZ|rcsb pdb:5CR7|rcsb pdb:5K7Y|rcsb pdb:5L4Z|rcsb pdb:5L50|rcsb pdb:5OPK|rcsb pdb:5OPL|rcsb pdb:5OPM|rcsb pdb:5OPN|rcsb pdb:5OPO|rcsb pdb:5OPP|rcsb pdb:6DD3|rcsb pdb:6DDB|rcsb pdb:6DDC|rcsb pdb:6DDH|rcsb pdb:6DDK|rcsb pdb:6DDL|ensembl:ENST00000676428(transcript)|rcsb pdb:6DDO|rcsb pdb:6DDQ|rcsb pdb:6DDX|rcsb pdb:6DDY|rcsb pdb:6DDZ|rcsb pdb:6DE0|rcsb pdb:6DE1|rcsb pdb:6DE2|rcsb pdb:6DE3|rcsb pdb:6FIR|rcsb pdb:6FIS|rcsb pdb:6FIU|rcsb pdb:6FIW|rcsb pdb:6FXH|reactome:R-HSA-2161541|reactome:R-HSA-74259|refseq:XP_005269693.1|refseq:XP_005269696.1	-	crc64:1E023C18682805BC	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:N0W+wPvCsl01y0k8hJZ156LztOo559292	rogid:5CDp+/pOJ1IRk/ndDr4SGP0Ext89606	intact-crc:5B62C19A99FB98E4|rigid:W9yB3Ioq/6qjAeSCgael0VrS98k	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O43791	uniprotkb:P53278	intact:EBI-743549|uniprotkb:Q53HJ1|uniprotkb:B2R6S3|uniprotkb:D3DTW7|ensembl:ENSP00000240327|ensembl:ENSP00000377001|ensembl:ENSP00000420908|ensembl:ENSP00000424119|ensembl:ENSP00000425905|ensembl:ENSP00000426986|ensembl:ENSP00000499562	intact:EBI-23314|uniprotkb:D6VUR2|ensemblfungi:YGR130C	psi-mi:spop_human(display_long)|uniprotkb:HIB homolog 1(gene name synonym)|uniprotkb:Roadkill homolog 1(gene name synonym)|uniprotkb:SPOP(gene name)|psi-mi:SPOP(display_short)	psi-mi:yg3a_yeast(display_long)|uniprotkb:YGR130C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550264|imex:IM-24995-3137	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001007227.1|refseq:NP_001007228.1|refseq:NP_001007229.1|refseq:NP_001007230.1|refseq:NP_001007231.1|refseq:NP_003554.1|refseq:XP_005257780.1|refseq:XP_005257781.1|ensembl:ENSG00000121067(gene)|ensembl:ENST00000347630(transcript)|ensembl:ENST00000393328(transcript)|ensembl:ENST00000503676(transcript)|ensembl:ENST00000504102(transcript)|ensembl:ENST00000509079(transcript)|ensembl:ENST00000514121(transcript)|ensembl:ENST00000665825(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0016607"(nuclear speck)|go:"GO:0030162"(regulation of proteolysis)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR034089|mint:O43791|rcsb pdb:2CR2|rcsb pdb:3HQH|rcsb pdb:3HQI|rcsb pdb:3HQL|rcsb pdb:3HQM|rcsb pdb:3HSV|rcsb pdb:3HTM|rcsb pdb:3HU6|rcsb pdb:3IVB|rcsb pdb:3IVQ|rcsb pdb:3IVV|rcsb pdb:4EOZ|rcsb pdb:4HS2|rcsb pdb:4J8Z|rcsb pdb:4O1V|rcsb pdb:6F8F|rcsb pdb:6F8G|rcsb pdb:6I41|rcsb pdb:6I5P|rcsb pdb:6I68|rcsb pdb:6I7A|rcsb pdb:7D3D|rcsb pdb:7LIN|rcsb pdb:7LIO|rcsb pdb:7LIP|rcsb pdb:7LIQ|reactome:R-HSA-5632684|go:"GO:0005634"(nucleus)|refseq:XP_016880693.1|dip:DIP-50517N	refseq:NP_011646.1|sgd:S000003362|dip:DIP-3006N|mint:P53278|ensemblfungi:YGR130C(gene)|ensemblfungi:YGR130C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0032126"(eisosome)	-	-	crc64:D482327C9274C026	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:PC9ofpvk14xwTnnqT590/YRnx/49606	rogid:iTa1C3VXvI8QteEEgkfjQDp9gvY559292	intact-crc:81C75BA04BE2D0BD|rigid:XtueZT1ahsSmPIYF7JfJWCuO+cQ	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O95198	uniprotkb:P53202	intact:EBI-746999|uniprotkb:B2RD18|uniprotkb:Q8N484|uniprotkb:Q8TBH5|uniprotkb:A6NCM7|uniprotkb:B4DFH7|uniprotkb:F5H6M3|ensembl:ENSP00000226725	intact:EBI-23065|uniprotkb:D6VUE0|ensemblfungi:YGR003W	psi-mi:klhl2_human(display_long)|uniprotkb:Actin-binding protein Mayven(gene name synonym)|uniprotkb:KLHL2(gene name)|psi-mi:KLHL2(display_short)	psi-mi:cul3_yeast(display_long)|uniprotkb:CUL3(gene name)|psi-mi:CUL3(display_short)|uniprotkb:Cullin-B(gene name synonym)|uniprotkb:YGR003W(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550260|imex:IM-24995-3136	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001154993.1|refseq:NP_001154994.1|refseq:NP_009177.3|refseq:NP_001317952.1|refseq:NP_001317953.1|refseq:XP_016863165.1|ensembl:ENSG00000109466(gene)|ensembl:ENST00000226725(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030027"(lamellipodium)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR017096(Kelch-like protein, gigaxonin)|interpro:IPR044072|mint:O95198|rcsb pdb:2XN4|rcsb pdb:4CHB|reactome:R-HSA-8951664|reactome:R-HSA-983168|go:"GO:0042802"(identical protein binding)	refseq:NP_011517.1|sgd:S000003235|dip:DIP-5506N|mint:P53202|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|ensemblfungi:YGR003W(gene)|ensemblfungi:YGR003W_mRNA(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:tFegR2lJZccRqs4qUjdT3PNjNnk9606	rogid:FvYjEpmLA9mF35UTi97nLZwp0eE559292	intact-crc:7E44DCBA7E2D39D1|rigid:4KFd6cGaEu7kzWvz7zzXloqu8ak	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O43791	uniprotkb:P53202	intact:EBI-743549|uniprotkb:Q53HJ1|uniprotkb:B2R6S3|uniprotkb:D3DTW7|ensembl:ENSP00000240327|ensembl:ENSP00000377001|ensembl:ENSP00000420908|ensembl:ENSP00000424119|ensembl:ENSP00000425905|ensembl:ENSP00000426986|ensembl:ENSP00000499562	intact:EBI-23065|uniprotkb:D6VUE0|ensemblfungi:YGR003W	psi-mi:spop_human(display_long)|uniprotkb:HIB homolog 1(gene name synonym)|uniprotkb:Roadkill homolog 1(gene name synonym)|uniprotkb:SPOP(gene name)|psi-mi:SPOP(display_short)	psi-mi:cul3_yeast(display_long)|uniprotkb:CUL3(gene name)|psi-mi:CUL3(display_short)|uniprotkb:Cullin-B(gene name synonym)|uniprotkb:YGR003W(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550256|imex:IM-24995-3135	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001007227.1|refseq:NP_001007228.1|refseq:NP_001007229.1|refseq:NP_001007230.1|refseq:NP_001007231.1|refseq:NP_003554.1|refseq:XP_005257780.1|refseq:XP_005257781.1|ensembl:ENSG00000121067(gene)|ensembl:ENST00000347630(transcript)|ensembl:ENST00000393328(transcript)|ensembl:ENST00000503676(transcript)|ensembl:ENST00000504102(transcript)|ensembl:ENST00000509079(transcript)|ensembl:ENST00000514121(transcript)|ensembl:ENST00000665825(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0016607"(nuclear speck)|go:"GO:0030162"(regulation of proteolysis)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR034089|mint:O43791|rcsb pdb:2CR2|rcsb pdb:3HQH|rcsb pdb:3HQI|rcsb pdb:3HQL|rcsb pdb:3HQM|rcsb pdb:3HSV|rcsb pdb:3HTM|rcsb pdb:3HU6|rcsb pdb:3IVB|rcsb pdb:3IVQ|rcsb pdb:3IVV|rcsb pdb:4EOZ|rcsb pdb:4HS2|rcsb pdb:4J8Z|rcsb pdb:4O1V|rcsb pdb:6F8F|rcsb pdb:6F8G|rcsb pdb:6I41|rcsb pdb:6I5P|rcsb pdb:6I68|rcsb pdb:6I7A|rcsb pdb:7D3D|rcsb pdb:7LIN|rcsb pdb:7LIO|rcsb pdb:7LIP|rcsb pdb:7LIQ|reactome:R-HSA-5632684|go:"GO:0005634"(nucleus)|refseq:XP_016880693.1|dip:DIP-50517N	refseq:NP_011517.1|sgd:S000003235|dip:DIP-5506N|mint:P53202|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|ensemblfungi:YGR003W(gene)|ensemblfungi:YGR003W_mRNA(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:PC9ofpvk14xwTnnqT590/YRnx/49606	rogid:FvYjEpmLA9mF35UTi97nLZwp0eE559292	intact-crc:865D246C59A8A211|rigid:zQaCFGgNUtTlFHC9ppqESiQzvUs	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P53140	uniprotkb:P43355	intact:EBI-23904|uniprotkb:Q66RA9|uniprotkb:D6VU39|ensemblfungi:YGL107C	intact:EBI-740978|ensembl:ENSP00000349085|uniprotkb:O00346|uniprotkb:B2RC81	psi-mi:rmd9_yeast(display_long)|uniprotkb:YGL107C(locus name)|uniprotkb:G3075(orf name)|uniprotkb:RMD9(gene name)|psi-mi:RMD9(display_short)|uniprotkb:Required for meiotic nuclear division protein 9(gene name synonym)	psi-mi:maga1_human(display_long)|uniprotkb:MAGE-1 antigen(gene name synonym)|uniprotkb:Antigen MZ2-E(gene name synonym)|uniprotkb:Cancer/testis antigen 1.1(gene name synonym)|uniprotkb:MAGEA1(gene name)|psi-mi:MAGEA1(display_short)|uniprotkb:MAGE1(gene name synonym)|uniprotkb:MAGE1A(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550252|imex:IM-24995-3134	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003075|refseq:NP_011408.1|interpro:IPR011990(Tetratricopeptide-like helical)|ensemblfungi:YGL107C(gene)|ensemblfungi:YGL107C_mRNA(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006413"(translational initiation)|go:"GO:0009060"(aerobic respiration)|go:"GO:0030435"(sporulation resulting in formation of a cellular spore)|go:"GO:0031314"(extrinsic component of mitochondrial inner membrane)|go:"GO:0043488"(regulation of mRNA stability)|rcsb pdb:7A9W|rcsb pdb:7A9X	refseq:NP_004979.3|ensembl:ENSG00000198681(gene)|ensembl:ENST00000356661(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|interpro:IPR002190(MAGE protein)|interpro:IPR021072|interpro:IPR030093|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|rcsb pdb:1W72|rcsb pdb:3BO8|dip:DIP-54794N	-	-	crc64:544EEB1F9F4E9D33	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:iO06ej1OrtaTNHBwQQFnMVZ1r1g559292	rogid:6XW3mnTNM3yvOtXmiFbU8Uz3hjA9606	intact-crc:1DA904FB6B5BC88D|rigid:5UBKUn8pyW5c8uX9ViH3Y8IOGZQ	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P53102	uniprotkb:P43355	intact:EBI-24091|uniprotkb:D6VTX1|ensemblfungi:YGL183C	intact:EBI-740978|ensembl:ENSP00000349085|uniprotkb:O00346|uniprotkb:B2RC81	psi-mi:mnd1_yeast(display_long)|uniprotkb:MND1(gene name)|psi-mi:MND1(display_short)|uniprotkb:G1604(orf name)|uniprotkb:YGL183C(locus name)	psi-mi:maga1_human(display_long)|uniprotkb:MAGE-1 antigen(gene name synonym)|uniprotkb:Antigen MZ2-E(gene name synonym)|uniprotkb:Cancer/testis antigen 1.1(gene name synonym)|uniprotkb:MAGEA1(gene name)|psi-mi:MAGEA1(display_short)|uniprotkb:MAGE1(gene name synonym)|uniprotkb:MAGE1A(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550248|imex:IM-24995-3133	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011332.2|sgd:S000003151|dip:DIP-2673N|ensemblfungi:YGL183C(gene)|ensemblfungi:YGL183C_mRNA(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0007131"(reciprocal meiotic recombination)|interpro:IPR005647(meiotic nuclear division protein 1)|interpro:IPR040453|interpro:IPR040661	refseq:NP_004979.3|ensembl:ENSG00000198681(gene)|ensembl:ENST00000356661(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|interpro:IPR002190(MAGE protein)|interpro:IPR021072|interpro:IPR030093|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|rcsb pdb:1W72|rcsb pdb:3BO8|dip:DIP-54794N	-	-	crc64:544EEB1F9F4E9D33	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:wGVAo4LTwqSnDsJ+/xC3qIMqZ0k559292	rogid:6XW3mnTNM3yvOtXmiFbU8Uz3hjA9606	intact-crc:644CDAD72AD38A46|rigid:B89B+XW3buuhr1+8kP6E7kSredc	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P53051	uniprotkb:P38646	intact:EBI-10464|ensemblfungi:YGR287C|uniprotkb:Q76CZ0|uniprotkb:D6VV64	intact:EBI-354932|ensembl:ENSP00000297185|uniprotkb:P30036|uniprotkb:P31932|uniprotkb:Q6GU03|uniprotkb:Q9BWB7|uniprotkb:B2RCM1|uniprotkb:Q1HB43|uniprotkb:Q53H23|uniprotkb:Q9UC56	psi-mi:malx3_yeast(display_long)|uniprotkb:YGR287C(locus name)|uniprotkb:IMA1(gene name)|psi-mi:IMA1(display_short)|uniprotkb:Alpha-glucosidase(gene name synonym)|uniprotkb:Isomaltase 1(gene name synonym)	psi-mi:grp75_human(display_long)|uniprotkb:HSPA9(gene name)|psi-mi:HSPA9(display_short)|uniprotkb:GRP75(gene name synonym)|uniprotkb:HSPA9B(gene name synonym)|uniprotkb:75 kDa glucose-regulated protein(gene name synonym)|uniprotkb:Heat shock 70 kDa protein 9(gene name synonym)|uniprotkb:Peptide-binding protein 74(gene name synonym)|uniprotkb:Mortalin(gene name synonym)|uniprotkb:mt-HSP70(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550244|imex:IM-24995-3132	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003519|interpro:IPR006047(Glycosyl hydrolase, family 13, catalytic region)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|rcsb pdb:3A47|rcsb pdb:3A4A|rcsb pdb:3AJ7|ensemblfungi:YGR287C(gene)|ensemblfungi:YGR287C_mRNA(transcript)|go:"GO:0000025"(maltose catabolic process)|go:"GO:0004556"(alpha-amylase activity)|go:"GO:0004574"(oligo-1,6-glucosidase activity)|go:"GO:0004575"(sucrose alpha-glucosidase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005987"(sucrose catabolic process)|go:"GO:0009313"(oligosaccharide catabolic process)|go:"GO:0032450"(maltose alpha-glucosidase activity)|go:"GO:0033934"(glucan 1,4-alpha-maltotriohydrolase activity)|go:"GO:0046352"(disaccharide catabolic process)|rcsb pdb:3AXH|rcsb pdb:3AXI|refseq:NP_011803.3|interpro:IPR013780(Glycosyl hydrolase, family 13, all-beta)|reactome:R-SCE-352230	reactome:R-HSA-8949613|reactome:R-HSA-8950505|ensembl:ENSG00000113013(gene)|ensembl:ENST00000297185(transcript)|go:"GO:0001401"(SAM complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005925"(focal adhesion)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0007007"(inner mitochondrial membrane organization)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045646"(regulation of erythrocyte differentiation)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0140275"(MIB complex)|go:"GO:1902037"(negative regulation of hematopoietic stem cell differentiation)|go:"GO:1903707"(negative regulation of hemopoiesis)|interpro:IPR012725(Chaperone DnaK)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|go:"GO:0070062"(extracellular exosome)|interpro:IPR043129|mint:P38646|rcsb pdb:3N8E|rcsb pdb:4KBO|rcsb pdb:6NHK|rcsb pdb:6P2U|rcsb pdb:6PMT|reactome:R-HSA-1268020|reactome:R-HSA-3371453|refseq:NP_004125.3|dip:DIP-32936N	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:FhUpCS+n2c22jDt6Ai5m93wM3/w559292	rogid:xjSHeTKBb/lH1XNEEiMIjsM+XcE9606	intact-crc:044771D66047FB59|rigid:Dkd2c8EWAskYKCAFjynK6eERRZM	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:J3KQ12	uniprotkb:P52870	intact:EBI-11532900|ensembl:ENSP00000385332	intact:EBI-16410|ensemblfungi:YER087C-B|uniprotkb:D3DLZ4	psi-mi:j3kq12_human(display_long)|uniprotkb:hCG_2020143(orf name)|uniprotkb:BSCL2(gene name)|psi-mi:BSCL2(display_short)	psi-mi:sc6b1_yeast(display_long)|uniprotkb:Sec61 complex subunit SBH1(gene name synonym)|uniprotkb:YER087BC(orf name)|uniprotkb:YER087C-B(locus name)|uniprotkb:SBH1(gene name)|psi-mi:SBH1(display_short)|uniprotkb:SEB1(gene name synonym)|uniprotkb:Sec61 complex subunit beta(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550240|imex:IM-24995-3131	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000168000(gene)|ensembl:ENST00000405837(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019915"(lipid storage)|interpro:IPR009617(Protein of unknown function DUF1226)	ensemblfungi:YER087C-B(gene)|ensemblfungi:YER087C-B_mRNA(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|interpro:IPR016482(Preprotein translocase Sec, Sec61-beta subunit, eukarya)|interpro:IPR030671|rcsb pdb:6N3Q|rcsb pdb:6ND1|rcsb pdb:7AFT|rcsb pdb:7KAH|rcsb pdb:7KAI|sgd:S000002128|rcsb pdb:7KAJ|rcsb pdb:7KAO|rcsb pdb:7KAP|rcsb pdb:7KAQ|rcsb pdb:7KAR|rcsb pdb:7KAS|rcsb pdb:7KAT|rcsb pdb:7KAU|rcsb pdb:7KB5|refseq:NP_011011.3|dip:DIP-5681N|mint:P52870	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:/q8SqeciXG5EVZxzVJRfX6gvRjY9606	rogid:9cYnDPhmMpAOdB2GV5TxikzpjI0559292	intact-crc:2511E8C5297983A5|rigid:Qy2mgAPlh4qPTWcLYn9Ed+TxEzo	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P20676	uniprotkb:P51116	intact:EBI-12392|ensemblfungi:YOR098C|uniprotkb:D6W2F9	intact:EBI-740459|uniprotkb:Q8WUM2|uniprotkb:Q86V09|uniprotkb:B2R9M2|uniprotkb:D3DTQ1|ensembl:ENSP00000250113	psi-mi:nup1_yeast(display_long)|uniprotkb:NUP1(gene name)|psi-mi:NUP1(display_short)|uniprotkb:YOR098C(locus name)|uniprotkb:YOR3182C(orf name)|uniprotkb:Nuclear pore protein NUP1(gene name synonym)	psi-mi:fxr2_human(display_long)|uniprotkb:FXR2(gene name)|psi-mi:FXR2(display_short)|uniprotkb:FMR1L2(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550236|imex:IM-24995-3130	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YOR098C(gene)|ensemblfungi:YOR098C_mRNA(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000972"(transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0005643"(nuclear pore)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0044615"(nuclear pore nuclear basket)|interpro:IPR026054|rcsb pdb:4C31|rcsb pdb:4MBE|rcsb pdb:5OWU|go:"GO:0006607"(NLS-bearing protein import into nucleus)|refseq:NP_014741.1|sgd:S000005624|mint:P20676|dip:DIP-81N	interpro:IPR004087(K Homology)|refseq:NP_004851.2|ensembl:ENSG00000129245(gene)|ensembl:ENST00000250113(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0044326"(dendritic spine neck)|go:"GO:0045182"(translation regulator activity)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0098793"(presynapse)|go:"GO:1902737"(dendritic filopodium)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|interpro:IPR004088(K Homology, type 1)|interpro:IPR008395(Agenet)|interpro:IPR022034|interpro:IPR032172|interpro:IPR036612|interpro:IPR040148|interpro:IPR040472|interpro:IPR041560|mint:P51116|rcsb pdb:3H8Z	-	crc64:4AC23567D2FB53CC	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:X1AjTIzoXjQ7vXlKzI88m7xfu6w559292	rogid:NnYgyzD2NRGIO1ZHukr5qy44qRE9606	intact-crc:8D7A8831BE334D7A|rigid:EiytHB1z8daib+C292mqC/9Yc/o	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P49366	uniprotkb:P53331	intact:EBI-741925|ensembl:ENSP00000210060|uniprotkb:Q13184|uniprotkb:Q13276|uniprotkb:A8K688|uniprotkb:Q9UDG0|uniprotkb:M0R1I5	intact:EBI-23641|uniprotkb:D6VV53|ensemblfungi:YGR276C	psi-mi:dhys_human(display_long)|uniprotkb:DHPS(gene name)|psi-mi:DHPS(display_short)|uniprotkb:DS(gene name synonym)	psi-mi:rexo1_yeast(display_long)|uniprotkb:YGR276C(locus name)|uniprotkb:G9381(orf name)|uniprotkb:RNH70(gene name)|psi-mi:RNH70(display_short)|uniprotkb:REX1(gene name synonym)|uniprotkb:"RNase H(70)"(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550292|imex:IM-24995-3144	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001193903.1|ensembl:ENSG00000095059(gene)|ensembl:ENST00000210060(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0008216"(spermidine metabolic process)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008612"(peptidyl-lysine modification to peptidyl-hypusine)|go:"GO:0034038"(deoxyhypusine synthase activity)|go:"GO:0042802"(identical protein binding)|interpro:IPR002773(Deoxyhypusine synthase)|interpro:IPR029035|interpro:IPR036982|mint:P49366|rcsb pdb:1DHS|rcsb pdb:1RLZ|rcsb pdb:1ROZ|rcsb pdb:1RQD|refseq:NP_001921.1|refseq:NP_037538.1|rcsb pdb:6P4V|rcsb pdb:6PGR|rcsb pdb:6WKZ|rcsb pdb:6WL6|rcsb pdb:6XXH|rcsb pdb:6XXI|rcsb pdb:6XXJ|rcsb pdb:6XXK|rcsb pdb:6XXL|rcsb pdb:6XXM|reactome:R-HSA-204626|refseq:XP_011526072.1	refseq:NP_011792.1|sgd:S000003508|dip:DIP-5564N|ensemblfungi:YGR276C(gene)|ensemblfungi:YGR276C_mRNA(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0002107"(generation of mature 3'-end of 5S rRNA generated by RNA polymerase III)|go:"GO:0003723"(RNA binding)|go:"GO:0004527"(exonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0008408"(3'-5' exonuclease activity)|go:"GO:0034415"(tRNA 3'-trailer cleavage, exonucleolytic)|go:"GO:0034476"(U5 snRNA 3'-end processing)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR013520(Exonuclease, RNase T and DNA polymerase III)|interpro:IPR034922|interpro:IPR036397	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:4MuV3m6JWYn3kCENrfcLU6GAkto9606	rogid:mkFn9c/1OdcUX9TOL2m2kGd0K90559292	intact-crc:C93AD9C4155F8A2B|rigid:2iJTqgivkLzk6BO5esa3v2uJU0s	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O14641	uniprotkb:P53305	intact:EBI-740850|ensembl:ENSP00000005340|uniprotkb:Q53XM0|uniprotkb:D3DTN3	intact:EBI-23490|uniprotkb:D6VUZ8|ensemblfungi:YGR215W	psi-mi:dvl2_human(display_long)|uniprotkb:DSH homolog 2(gene name synonym)|uniprotkb:DVL2(gene name)|psi-mi:DVL2(display_short)	psi-mi:rt27_yeast(display_long)|uniprotkb:RSM27(gene name)|psi-mi:RSM27(display_short)|uniprotkb:Mitochondrial small ribosomal subunit protein mS33(gene name synonym)|uniprotkb:YGR215W(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550288|imex:IM-24995-3143	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004413.1|ensembl:ENSG00000004975(gene)|ensembl:ENST00000005340(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005109"(frizzled binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0007507"(heart development)|go:"GO:0016235"(aggresome)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044340"(canonical Wnt signaling pathway involved in regulation of cell proliferation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0150012"(positive regulation of neuron projection arborization)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008341(Dishevelled-2 region)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:O14641|rcsb pdb:2REY|rcsb pdb:3CBX|rcsb pdb:3CBY|rcsb pdb:3CBZ|rcsb pdb:3CC0|rcsb pdb:4WIP|rcsb pdb:5LNP|rcsb pdb:5SUY|rcsb pdb:5SUZ|rcsb pdb:6IW3|rcsb pdb:6JCK|reactome:R-HSA-201681|reactome:R-HSA-201688|reactome:R-HSA-2028269|reactome:R-HSA-4086400|reactome:R-HSA-4608870|reactome:R-HSA-4641258|reactome:R-HSA-4641262|reactome:R-HSA-5099900|reactome:R-HSA-5368598|reactome:R-HSA-5663220|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9673324|ensembl:ENSP00000005340|dip:DIP-34433N	sgd:S000003447|refseq:NP_011731.3|dip:DIP-5606N|mint:P53305|ensemblfungi:YGR215W(gene)|ensemblfungi:YGR215W_mRNA(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR013219(Ribosomal protein S27, mitochondrial)|rcsb pdb:5MRC|rcsb pdb:5MRE|rcsb pdb:5MRF	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:2Vdc8oRnT4Mz/j+EXQXrL3AszOc9606	rogid:IRBztDEm6s+cFbpp3GkrlJgUdp4559292	intact-crc:81C059E7D8AFBA90|rigid:1lEmCr91dLNwbHoUQylCqMMvyNk	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
intact:EBI-11533440	uniprotkb:P53296	-	intact:EBI-3165|uniprotkb:E9P955|ensemblfungi:YGR177C|uniprotkb:D6VUW1	psi-mi:wac(display_short)|psi-mi:EBI-11533440(display_long)	psi-mi:atf2_yeast(display_long)|uniprotkb:ATF2(gene name)|psi-mi:ATF2(display_short)|uniprotkb:"Acetyl-CoA:pregnenolone acetyltransferase"(gene name synonym)|uniprotkb:G7135(orf name)|uniprotkb:YGR177C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550284|imex:IM-24995-3142	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	-	refseq:NP_011693.1|sgd:S000003409|ensemblfungi:YGR177C(gene)|ensemblfungi:YGR177C_mRNA(transcript)|go:"GO:0004026"(alcohol O-acetyltransferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0008080"(N-acetyltransferase activity)|go:"GO:0008202"(steroid metabolic process)|go:"GO:0009636"(response to toxic substance)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0034209"(sterol acetylation)|go:"GO:1901089"(acetate ester metabolic process involved in fermentation)|interpro:IPR010828(Alcohol acetyltransferase)|dip:DIP-5544N|mint:P53296	-	no-uniprot-update:	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:1lJ64iBkqUGKNB4Lz3jsp7Xu2nE9606	rogid:tFI+2rcFXzDfDteDJv8wwBGUh0c559292	intact-crc:F41A8F7498D3B282|rigid:trBMDDEA9DoT5CNCQ5Q/nxnBYo8	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P53286	uniprotkb:Q8N5R6	intact:EBI-3796|uniprotkb:D6VUS2|ensemblfungi:YGR142W	intact:EBI-740841|intact:EBI-953781|uniprotkb:B3KQ49|uniprotkb:A8K3U4|uniprotkb:A8MPQ6|uniprotkb:A8MV61|uniprotkb:A8MVU9|uniprotkb:Q9H5Q6|uniprotkb:Q8TAX6|intact:EBI-2320546|intact:EBI-11522976	psi-mi:btn2_yeast(display_long)|uniprotkb:YGR142W(locus name)|uniprotkb:BTN2(gene name)|psi-mi:BTN2(display_short)|uniprotkb:Batten disease protein 2(gene name synonym)	psi-mi:ccd33_human(display_long)|uniprotkb:CCDC33(gene name)|psi-mi:CCDC33(display_short)|uniprotkb:Cancer/testis antigen 61(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550268|imex:IM-24995-3138	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003374|refseq:NP_011658.3|dip:DIP-5534N|mint:P53286|ensemblfungi:YGR142W(gene)|ensemblfungi:YGR142W_mRNA(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005634"(nucleus)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006865"(amino acid transport)|go:"GO:0006885"(regulation of pH)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051087"(chaperone binding)|go:"GO:0140311"(protein sequestering activity)	refseq:NP_079331.3|interpro:IPR000008(C2 calcium-dependent membrane targeting)|go:"GO:0005777"(peroxisome)|refseq:NP_001274110.1|refseq:NP_877592.2|mint:Q8N5R6|interpro:IPR035892|interpro:IPR039889	-	crc64:E7AE1EB1E3612F3E	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2021/11/30	rogid:Cu27xkwGMNyS4zLvUaG1UeH2mE0559292	rogid:eEIn7pQyfdHWx8TeLJpYy0i/gww9606	intact-crc:6B664FC1A1A276AC|rigid:JS2g2RcnPmP5C7qNkAk1VjyMSKE	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P53286	uniprotkb:P14373	intact:EBI-3796|uniprotkb:D6VUS2|ensemblfungi:YGR142W	intact:EBI-719493|uniprotkb:A2BE15|uniprotkb:Q5RJA8|uniprotkb:Q5ST26|uniprotkb:Q6LA73|uniprotkb:Q6NXR9|uniprotkb:Q9BZY6|uniprotkb:Q9UJL3|ensembl:ENSP00000383555|ensembl:ENSP00000392787|ensembl:ENSP00000405229|ensembl:ENSP00000414793|ensembl:ENSP00000366404	psi-mi:btn2_yeast(display_long)|uniprotkb:YGR142W(locus name)|uniprotkb:BTN2(gene name)|psi-mi:BTN2(display_short)|uniprotkb:Batten disease protein 2(gene name synonym)	psi-mi:tri27_human(display_long)|uniprotkb:TRIM27(gene name)|psi-mi:TRIM27(display_short)|uniprotkb:RNF76(gene name synonym)|uniprotkb:RFP(gene name synonym)|uniprotkb:Ret finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 27(gene name synonym)|uniprotkb:RING finger protein 76(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM27(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550276|imex:IM-24995-3140	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003374|refseq:NP_011658.3|dip:DIP-5534N|mint:P53286|ensemblfungi:YGR142W(gene)|ensemblfungi:YGR142W_mRNA(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005634"(nucleus)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006865"(amino acid transport)|go:"GO:0006885"(regulation of pH)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051087"(chaperone binding)|go:"GO:0140311"(protein sequestering activity)	refseq:NP_006501.1|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0090281"(negative regulation of calcium ion import)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR020457|interpro:IPR035791|interpro:IPR043136|mint:P14373|reactome:R-HSA-3232142|reactome:R-HSA-9635465|reactome:R-HSA-8948751|ensembl:ENSG00000204713(gene)|ensembl:ENSG00000215641(gene)|ensembl:ENSG00000229006(gene)|ensembl:ENSG00000234495(gene)|ensembl:ENSG00000237071(gene)|ensembl:ENST00000377199(transcript)|ensembl:ENST00000400720(transcript)|ensembl:ENST00000431123(transcript)|ensembl:ENST00000435528(transcript)|ensembl:ENST00000437160(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001650"(fibrillar center)|go:"GO:0002820"(negative regulation of adaptive immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)	-	crc64:E7AE1EB1E3612F3E	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Cu27xkwGMNyS4zLvUaG1UeH2mE0559292	rogid:dsfH5OUghD8KSaTz1SFw9OYVTK49606	intact-crc:3604DA16179AEBE1|rigid:EeK2OKS7QHYLx/SeETjhKZnWZCY	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:A0A0C4DGF1	uniprotkb:P53286	intact:EBI-10188476|ensembl:ENSP00000433657	intact:EBI-3796|uniprotkb:D6VUS2|ensemblfungi:YGR142W	psi-mi:a0a0c4dgf1_human(display_long)|uniprotkb:ZBTB32(gene name)|psi-mi:ZBTB32(display_short)	psi-mi:btn2_yeast(display_long)|uniprotkb:YGR142W(locus name)|uniprotkb:BTN2(gene name)|psi-mi:BTN2(display_short)|uniprotkb:Batten disease protein 2(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550272|imex:IM-24995-3139	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|ensembl:ENSG00000011590(gene)|ensembl:ENST00000481182(transcript)|go:"GO:0042802"(identical protein binding)	sgd:S000003374|refseq:NP_011658.3|dip:DIP-5534N|mint:P53286|ensemblfungi:YGR142W(gene)|ensemblfungi:YGR142W_mRNA(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005634"(nucleus)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006865"(amino acid transport)|go:"GO:0006885"(regulation of pH)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051087"(chaperone binding)|go:"GO:0140311"(protein sequestering activity)	-	-	crc64:E7AE1EB1E3612F3E	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:w3k7YT4kw/T+Xi5YBqGHSpHtwMM9606	rogid:Cu27xkwGMNyS4zLvUaG1UeH2mE0559292	intact-crc:430AD4037F893E0F|rigid:02tTGbPh1uOnYhZK9iXwT9tfYk4	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P53296	uniprotkb:O95197-3	intact:EBI-3165|uniprotkb:E9P955|ensemblfungi:YGR177C|uniprotkb:D6VUW1	intact:EBI-11525735|ensembl:ENSP00000440874	psi-mi:atf2_yeast(display_long)|uniprotkb:ATF2(gene name)|psi-mi:ATF2(display_short)|uniprotkb:"Acetyl-CoA:pregnenolone acetyltransferase"(gene name synonym)|uniprotkb:G7135(orf name)|uniprotkb:YGR177C(locus name)	psi-mi:o95197-3(display_long)|uniprotkb:RTN3(gene name)|psi-mi:RTN3(display_short)|uniprotkb:ASYIP(gene name synonym)|uniprotkb:Homolog of ASY protein(gene name synonym)|uniprotkb:NSPL2(gene name synonym)|uniprotkb:Neuroendocrine-specific protein-like 2(gene name synonym)|uniprotkb:Neuroendocrine-specific protein-like II(gene name synonym)|uniprotkb:A1(isoform synonym)|uniprotkb:B1(isoform synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550280|imex:IM-24995-3141	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011693.1|sgd:S000003409|ensemblfungi:YGR177C(gene)|ensemblfungi:YGR177C_mRNA(transcript)|go:"GO:0004026"(alcohol O-acetyltransferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0008080"(N-acetyltransferase activity)|go:"GO:0008202"(steroid metabolic process)|go:"GO:0009636"(response to toxic substance)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0034209"(sterol acetylation)|go:"GO:1901089"(acetate ester metabolic process involved in fermentation)|interpro:IPR010828(Alcohol acetyltransferase)|dip:DIP-5544N|mint:P53296	ensembl:ENSG00000133318(gene)|ensembl:ENST00000537981(transcript)|intact:EBI-740467(isoform-parent)|uniprotkb:O95197-3(isoform-parent)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:tFI+2rcFXzDfDteDJv8wwBGUh0c559292	rogid:+TJnANu85CM52dRZ6s+hYMlUABE9606	intact-crc:20F96223B33A659F|rigid:DyoaHsZ294v67cad9fx6YHSXQkY	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O14641	uniprotkb:P53617	intact:EBI-740850|ensembl:ENSP00000005340|uniprotkb:Q53XM0|uniprotkb:D3DTN3	intact:EBI-12228|ensemblfungi:YNL251C|uniprotkb:D6W0U2	psi-mi:dvl2_human(display_long)|uniprotkb:DSH homolog 2(gene name synonym)|uniprotkb:DVL2(gene name)|psi-mi:DVL2(display_short)	psi-mi:nrd1_yeast(display_long)|uniprotkb:N0868(orf name)|uniprotkb:YNL251C(locus name)|uniprotkb:NRD1(gene name)|psi-mi:NRD1(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550300|imex:IM-24995-3146	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004413.1|ensembl:ENSG00000004975(gene)|ensembl:ENST00000005340(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005109"(frizzled binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0007507"(heart development)|go:"GO:0016235"(aggresome)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044340"(canonical Wnt signaling pathway involved in regulation of cell proliferation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0150012"(positive regulation of neuron projection arborization)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008341(Dishevelled-2 region)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:O14641|rcsb pdb:2REY|rcsb pdb:3CBX|rcsb pdb:3CBY|rcsb pdb:3CBZ|rcsb pdb:3CC0|rcsb pdb:4WIP|rcsb pdb:5LNP|rcsb pdb:5SUY|rcsb pdb:5SUZ|rcsb pdb:6IW3|rcsb pdb:6JCK|reactome:R-HSA-201681|reactome:R-HSA-201688|reactome:R-HSA-2028269|reactome:R-HSA-4086400|reactome:R-HSA-4608870|reactome:R-HSA-4641258|reactome:R-HSA-4641262|reactome:R-HSA-5099900|reactome:R-HSA-5368598|reactome:R-HSA-5663220|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9673324|ensembl:ENSP00000005340|dip:DIP-34433N	ensemblfungi:YNL251C(gene)|ensemblfungi:YNL251C_mRNA(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001068"(transcription regulatory region RNA binding)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030847"(termination of RNA polymerase II transcription, exosome-dependent)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0031126"("sno(s)RNA 3'-end processing")|go:"GO:0034472"(snRNA 3'-end processing)|go:"GO:0035649"(Nrd1 complex)|go:"GO:0042780"(tRNA 3'-end processing)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071034"(CUT catabolic process)|go:"GO:0071041"(antisense RNA transcript catabolic process)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR006569(Regulation of nuclear pre-mRNA protein)|interpro:IPR008942(ENTH/VHS)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034894|interpro:IPR035979|rcsb pdb:2LO6|rcsb pdb:2M88|rcsb pdb:2MOW|rcsb pdb:3CLJ|rcsb pdb:5O1T|rcsb pdb:5O1W|rcsb pdb:5O1X|rcsb pdb:5O1Y|rcsb pdb:5O1Z|rcsb pdb:5O20|rcsb pdb:6GC3|rcsb pdb:6O3W|rcsb pdb:6O3X|rcsb pdb:6O3Y|refseq:NP_014148.1|sgd:S000005195|mint:P53617|dip:DIP-6778N	-	-	crc64:75082BDB0C42AE37	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:2Vdc8oRnT4Mz/j+EXQXrL3AszOc9606	rogid:FJJxQtZfVVwYERLXtGkq6cJ9I1U559292	intact-crc:BBAB766D3724ED1F|rigid:v77/dYwCC7t3dG3yE5DadupUjf0	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P50222	uniprotkb:P53583	intact:EBI-748397|uniprotkb:O75263|ensembl:ENSP00000262041|uniprotkb:Q9UPL6|uniprotkb:B2R8I7|intact:EBI-10172134|intact:EBI-11522964|intact:EBI-11750003|intact:EBI-12702266|uniprotkb:A4D127	intact:EBI-11174|uniprotkb:D6W0U4|ensemblfungi:YNL249C	psi-mi:meox2_human(display_long)|uniprotkb:Mesenchyme homeobox 2(gene name synonym)|uniprotkb:Growth arrest-specific homeobox(gene name synonym)|uniprotkb:MEOX2(gene name)|psi-mi:MEOX2(display_short)|uniprotkb:GAX(gene name synonym)|uniprotkb:MOX2(gene name synonym)	psi-mi:mpa43_yeast(display_long)|uniprotkb:N0875(orf name)|uniprotkb:YNL249C(locus name)|uniprotkb:MPA43(gene name)|psi-mi:MPA43(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550296|imex:IM-24995-3145	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000106511(gene)|ensembl:ENST00000262041(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0001757"(somite specification)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007275"(multicellular organism development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008015"(blood circulation)|go:"GO:0016607"(nuclear speck)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060173"(limb development)|go:"GO:0061053"(somite development)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR042634|refseq:NP_005915.2	ensemblfungi:YNL249C(gene)|ensemblfungi:YNL249C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0016773"(phosphotransferase activity, alcohol group as acceptor)|refseq:NP_014150.1|sgd:S000005193|interpro:IPR018485|interpro:IPR018484|interpro:IPR043129	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2017/05/26	rogid:fMv0ruKikzQ3MC0PBvJ3pOAjW+U9606	rogid:QQDVGr5IRob5uHE4ZvFNeyAgkZo559292	intact-crc:751D8F5CF4F03701|rigid:08riUNnYPva+PY8cYs0aWMzSTiE	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P53829	uniprotkb:P32321	intact:EBI-28306|uniprotkb:D6W0Q5|ensemblfungi:YNL288W	intact:EBI-739870|uniprotkb:Q9BVD8|uniprotkb:B2R836|uniprotkb:Q5M7Z8|uniprotkb:D3DP49|uniprotkb:D3DP50|ensembl:ENSP00000398194|ensembl:ENSP00000424017	psi-mi:caf40_yeast(display_long)|uniprotkb:YNL288W(locus name)|uniprotkb:N0540(orf name)|uniprotkb:40 kDa CCR4-associated factor(gene name synonym)|uniprotkb:CAF40(gene name)|psi-mi:CAF40(display_short)	psi-mi:dctd_human(display_long)|uniprotkb:DCTD(gene name)|psi-mi:DCTD(display_short)|uniprotkb:dCMP deaminase(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550332|imex:IM-24995-3154	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014111.1|sgd:S000005232|dip:DIP-1995N|mint:P53829|ensemblfungi:YNL288W(gene)|ensemblfungi:YNL288W_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR007216(Cell differentiation, Rcd1-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:4CV5	refseq:NP_001012750.1|refseq:NP_001912.2|ensembl:ENSG00000129187(gene)|ensembl:ENST00000438320(transcript)|ensembl:ENST00000510370(transcript)|go:"GO:0004132"(dCMP deaminase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006220"(pyrimidine nucleotide metabolic process)|go:"GO:0006226"(dUMP biosynthetic process)|go:"GO:0006231"(dTMP biosynthetic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR002125(CMP/dCMP deaminase, zinc-binding)|interpro:IPR015517(Cytidine deaminase)|interpro:IPR016192(APOBEC/CMP deaminase, zinc-binding)|interpro:IPR016193(Cytidine deaminase-like)|interpro:IPR016473(dCMP deaminase)|interpro:IPR035105|mint:P32321|rcsb pdb:2W4L|reactome:R-HSA-499943|refseq:XP_005262836.1|refseq:XP_005262837.1|refseq:XP_011529976.1|refseq:XP_016863305.1|refseq:XP_016863306.1|refseq:XP_016863307.1|refseq:XP_016863308.1|refseq:XP_016863309.1|refseq:XP_016863310.1|refseq:XP_016863311.1	-	crc64:F3DBABE6AD3C7F3C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:etuSSgFGQOcgxPDexEXUqQg6H5s559292	rogid:lU3gEi7XdIJbuPlMkForbVKEOyY9606	intact-crc:49EBDA8E6E76D0B7|rigid:AxSpZw9n6xa4SlD4PHm1ExQ6IVs	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P42575	uniprotkb:P53829	intact:EBI-520342|ensembl:ENSP00000312664|uniprotkb:P42576|uniprotkb:D3DXD6|uniprotkb:Q59F21|uniprotkb:Q7KZL6|uniprotkb:Q86UJ3|uniprotkb:Q9BUP7|uniprotkb:Q9BZK9|uniprotkb:A8K5F9|uniprotkb:E9PDN0|uniprotkb:Q9BZL0	intact:EBI-28306|uniprotkb:D6W0Q5|ensemblfungi:YNL288W	psi-mi:casp2_human(display_long)|uniprotkb:Protease ICH-1(gene name synonym)|uniprotkb:Neural precursor cell expressed developmentally down-regulated protein 2(gene name synonym)|uniprotkb:CASP2(gene name)|psi-mi:CASP2(display_short)|uniprotkb:ICH1(gene name synonym)|uniprotkb:NEDD2(gene name synonym)	psi-mi:caf40_yeast(display_long)|uniprotkb:YNL288W(locus name)|uniprotkb:N0540(orf name)|uniprotkb:40 kDa CCR4-associated factor(gene name synonym)|uniprotkb:CAF40(gene name)|psi-mi:CAF40(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550328|imex:IM-24995-3153	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000106144(gene)|ensembl:ENST00000310447(transcript)|go:"GO:0001554"(luteolysis)|go:"GO:0003407"(neural retina development)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0007420"(brain development)|go:"GO:0007568"(aging)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0016020"(membrane)|go:"GO:0016485"(protein processing)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0035234"(ectopic germ cell programmed cell death)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0097153"(cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0097192"(extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:0097194"(execution phase of apoptosis)|go:"GO:0097199"(cysteine-type endopeptidase activity involved in apoptotic signaling pathway)|go:"GO:0097200"(cysteine-type endopeptidase activity involved in execution phase of apoptosis)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR001309(Peptidase C14, ICE, catalytic subunit p20)|interpro:IPR001315(Caspase Recruitment)|interpro:IPR002138(Peptidase C14, caspase non-catalytic subunit p10)|interpro:IPR002398(Peptidase C14, caspase precursor p45)|interpro:IPR011029(DEATH-like)|interpro:IPR015917(Peptidase C14, caspase precursor p45, core)|interpro:IPR016129(Peptidase C14, ICE, catalytic subunit p20, active site)|interpro:IPR029030|interpro:IPR033139|interpro:IPR035702|rcsb pdb:1PYO|rcsb pdb:2P2C|rcsb pdb:3R5J|rcsb pdb:3R6G|rcsb pdb:3R6L|rcsb pdb:3R7B|rcsb pdb:3R7N|refseq:NP_001215.1|refseq:NP_116764.2|refseq:NP_116765.2|rcsb pdb:3R7S|rcsb pdb:3RJM|rcsb pdb:6GKF|rcsb pdb:6GKG|rcsb pdb:6S9K|rcsb pdb:6SAD|rcsb pdb:6Y8B|rcsb pdb:6Y8D|reactome:R-HSA-168638|reactome:R-HSA-205025|reactome:R-HSA-6803207	refseq:NP_014111.1|sgd:S000005232|dip:DIP-1995N|mint:P53829|ensemblfungi:YNL288W(gene)|ensemblfungi:YNL288W_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR007216(Cell differentiation, Rcd1-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:4CV5	-	-	crc64:F3DBABE6AD3C7F3C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:3WFvmDoYbW3J84Yd9RVGAOcR8ig9606	rogid:etuSSgFGQOcgxPDexEXUqQg6H5s559292	intact-crc:21D22A943A941E94|rigid:Ygl8eQbfjHfmfuTNoP01Z9Rqj1U	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P53617	uniprotkb:O95751	intact:EBI-12228|ensemblfungi:YNL251C|uniprotkb:D6W0U2	intact:EBI-740738|ensembl:ENSP00000359557|uniprotkb:Q6IAR6	psi-mi:nrd1_yeast(display_long)|uniprotkb:N0868(orf name)|uniprotkb:YNL251C(locus name)|uniprotkb:NRD1(gene name)|psi-mi:NRD1(display_short)	psi-mi:ldoc1_human(display_long)|uniprotkb:Leucine zipper protein down-regulated in cancer cells(gene name synonym)|uniprotkb:LDOC1(gene name)|psi-mi:LDOC1(display_short)|uniprotkb:BCUR1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550304|imex:IM-24995-3147	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YNL251C(gene)|ensemblfungi:YNL251C_mRNA(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001068"(transcription regulatory region RNA binding)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030847"(termination of RNA polymerase II transcription, exosome-dependent)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0031126"("sno(s)RNA 3'-end processing")|go:"GO:0034472"(snRNA 3'-end processing)|go:"GO:0035649"(Nrd1 complex)|go:"GO:0042780"(tRNA 3'-end processing)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071034"(CUT catabolic process)|go:"GO:0071041"(antisense RNA transcript catabolic process)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR006569(Regulation of nuclear pre-mRNA protein)|interpro:IPR008942(ENTH/VHS)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034894|interpro:IPR035979|rcsb pdb:2LO6|rcsb pdb:2M88|rcsb pdb:2MOW|rcsb pdb:3CLJ|rcsb pdb:5O1T|rcsb pdb:5O1W|rcsb pdb:5O1X|rcsb pdb:5O1Y|rcsb pdb:5O1Z|rcsb pdb:5O20|rcsb pdb:6GC3|rcsb pdb:6O3W|rcsb pdb:6O3X|rcsb pdb:6O3Y|refseq:NP_014148.1|sgd:S000005195|mint:P53617|dip:DIP-6778N	refseq:NP_036449.1|ensembl:ENSG00000182195(gene)|ensembl:ENST00000370526(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071225"(cellular response to muramyl dipeptide)|interpro:IPR032549|interpro:IPR032567	-	crc64:75082BDB0C42AE37	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:FJJxQtZfVVwYERLXtGkq6cJ9I1U559292	rogid:Ediu0oNiZ/+YVY8l3fNdgP5A+v09606	intact-crc:A9697A28EBE45122|rigid:EsLaDP+DGoWArV+Xn93wox8hmZs	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P37198	uniprotkb:P53829	intact:EBI-347978|intact:EBI-28983799|ensembl:ENSP00000305503|ensembl:ENSP00000407331|ensembl:ENSP00000471191|ensembl:ENSP00000473192|uniprotkb:Q6GTM2|uniprotkb:Q503A4|uniprotkb:Q96C43|uniprotkb:Q9NSL1|uniprotkb:B3KWU5	intact:EBI-28306|uniprotkb:D6W0Q5|ensemblfungi:YNL288W	psi-mi:nup62_human(display_long)|uniprotkb:NUP62(gene name)|psi-mi:NUP62(display_short)|uniprotkb:62 kDa nucleoporin(gene name synonym)|uniprotkb:Nucleoporin Nup62(gene name synonym)	psi-mi:caf40_yeast(display_long)|uniprotkb:YNL288W(locus name)|uniprotkb:N0540(orf name)|uniprotkb:40 kDa CCR4-associated factor(gene name synonym)|uniprotkb:CAF40(gene name)|psi-mi:CAF40(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550320|imex:IM-24995-3151	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_714941.1|ensembl:ENSG00000213024(gene)|ensembl:ENST00000352066(transcript)|ensembl:ENST00000422090(transcript)|ensembl:ENST00000596217(transcript)|ensembl:ENST00000597029(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005642"(annulate lamellae)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007100"(mitotic centrosome separation)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007569"(cell aging)|go:"GO:0008219"(cell death)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0003682"(chromatin binding)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0019894"(kinesin binding)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042306"(regulation of protein import into nucleus)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043069"(negative regulation of programmed cell death)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045742"(positive regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046578"(regulation of Ras protein signal transduction)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0046601"(positive regulation of centriole replication)|go:"GO:0051028"(mRNA transport)|go:"GO:0051425"(PTB domain binding)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0072686"(mitotic spindle)|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|go:"GO:0090543"(Flemming body)|go:"GO:0098534"(centriole assembly)|go:"GO:1903438"(positive regulation of mitotic cytokinetic process)|go:"GO:1904781"(positive regulation of protein localization to centrosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR007758(Nucleoporin, Nsp1-like, C-terminal)|interpro:IPR026010|interpro:IPR033072|mint:P37198|rcsb pdb:2H4D|rcsb pdb:5IJN|rcsb pdb:5IJO|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|refseq:NP_714940.1|refseq:NP_001180286.1|refseq:NP_036478.2|refseq:NP_057637.2|ensembl:ENSP00000305503|ensembl:ENSP00000407331|ensembl:ENSP00000471191|ensembl:ENSP00000473192|dip:DIP-29749N	refseq:NP_014111.1|sgd:S000005232|dip:DIP-1995N|mint:P53829|ensemblfungi:YNL288W(gene)|ensemblfungi:YNL288W_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR007216(Cell differentiation, Rcd1-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:4CV5	-	-	crc64:F3DBABE6AD3C7F3C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:v7mvKvTtVEnLMwcpUZIcdAzge009606	rogid:etuSSgFGQOcgxPDexEXUqQg6H5s559292	intact-crc:3C8264FB7A9448F0|rigid:0qAntt6PSBiPdBfSNgOEoe/3fxI	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P53829	uniprotkb:P14136	intact:EBI-28306|uniprotkb:D6W0Q5|ensemblfungi:YNL288W	intact:EBI-744302|uniprotkb:Q53H98|uniprotkb:Q5D055|uniprotkb:Q6ZQS3|uniprotkb:Q7Z5J6|uniprotkb:Q7Z5J7|uniprotkb:Q96KS4|uniprotkb:Q96P18|uniprotkb:Q9UFD0|uniprotkb:B2RD44|uniprotkb:D3DX59|intact:EBI-3909365|uniprotkb:E9PAX3|ensembl:ENSP00000466598|uniprotkb:A7REI1	psi-mi:caf40_yeast(display_long)|uniprotkb:YNL288W(locus name)|uniprotkb:N0540(orf name)|uniprotkb:40 kDa CCR4-associated factor(gene name synonym)|uniprotkb:CAF40(gene name)|psi-mi:CAF40(display_short)	psi-mi:gfap_human(display_long)|uniprotkb:GFAP(gene name)|psi-mi:GFAP(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550316|imex:IM-24995-3150	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014111.1|sgd:S000005232|dip:DIP-1995N|mint:P53829|ensemblfungi:YNL288W(gene)|ensemblfungi:YNL288W_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR007216(Cell differentiation, Rcd1-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:4CV5	refseq:NP_001124491.1|refseq:NP_001229305.1|refseq:NP_002046.1|ensembl:ENSG00000131095(gene)|ensembl:ENST00000588735(transcript)|go:"GO:0005178"(integrin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0009611"(response to wounding)|go:"GO:0010467"(gene expression)|go:"GO:0010625"(positive regulation of Schwann cell proliferation)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0014002"(astrocyte development)|go:"GO:0019900"(kinase binding)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0031102"(neuron projection regeneration)|go:"GO:0042802"(identical protein binding)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0044297"(cell body)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0051580"(regulation of neurotransmitter uptake)|go:"GO:0060020"(Bergmann glial cell differentiation)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0070779"(D-aspartate import across plasma membrane)|go:"GO:0097450"(astrocyte end-foot)|go:"GO:0098574"(cytoplasmic side of lysosomal membrane)|go:"GO:1904714"(regulation of chaperone-mediated autophagy)|interpro:IPR006821(Intermediate filament, DNA-binding region)|interpro:IPR018039|interpro:IPR027701|interpro:IPR039008|mint:P14136|rcsb pdb:6A9P|reactome:R-HSA-1251985|reactome:R-HSA-9613829	-	crc64:F3DBABE6AD3C7F3C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:etuSSgFGQOcgxPDexEXUqQg6H5s559292	rogid:Pz4JW0WjMjBYILTDSX9jUmMqWhg9606	intact-crc:50B5F038411AE26A|rigid:C0lpqj92CSG9FmNjEftjqDxKnp8	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P53829	uniprotkb:P00492	intact:EBI-28306|uniprotkb:D6W0Q5|ensemblfungi:YNL288W	intact:EBI-748210|uniprotkb:A6NHF0|uniprotkb:B2R8M9|ensembl:ENSP00000298556	psi-mi:caf40_yeast(display_long)|uniprotkb:YNL288W(locus name)|uniprotkb:N0540(orf name)|uniprotkb:40 kDa CCR4-associated factor(gene name synonym)|uniprotkb:CAF40(gene name)|psi-mi:CAF40(display_short)	psi-mi:hprt_human(display_long)|uniprotkb:HPRT1(gene name)|psi-mi:HPRT1(display_short)|uniprotkb:HPRT(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550312|imex:IM-24995-3149	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014111.1|sgd:S000005232|dip:DIP-1995N|mint:P53829|ensemblfungi:YNL288W(gene)|ensemblfungi:YNL288W_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR007216(Cell differentiation, Rcd1-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:4CV5	refseq:NP_000185.1|ensembl:ENSG00000165704(gene)|ensembl:ENST00000298556(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001913"(T cell mediated cytotoxicity)|go:"GO:0001975"(response to amphetamine)|go:"GO:0004422"(hypoxanthine phosphoribosyltransferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006164"(purine nucleotide biosynthetic process)|go:"GO:0006166"(purine ribonucleoside salvage)|go:"GO:0006168"(adenine salvage)|go:"GO:0006178"(guanine salvage)|go:"GO:0007625"(grooming behavior)|go:"GO:0007626"(locomotory behavior)|go:"GO:0021756"(striatum development)|go:"GO:0021895"(cerebral cortex neuron differentiation)|go:"GO:0021954"(central nervous system neuron development)|go:"GO:0032263"(GMP salvage)|go:"GO:0032264"(IMP salvage)|go:"GO:0042417"(dopamine metabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043103"(hypoxanthine salvage)|go:"GO:0045964"(positive regulation of dopamine metabolic process)|go:"GO:0046038"(GMP catabolic process)|go:"GO:0046040"(IMP metabolic process)|go:"GO:0046100"(hypoxanthine metabolic process)|go:"GO:0046651"(lymphocyte proliferation)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0052657"(guanine phosphoribosyltransferase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000836(Phosphoribosyltransferase)|interpro:IPR005904(Hypoxanthine phosphoribosyl transferase)|interpro:IPR029057|mint:P00492|rcsb pdb:1BZY|rcsb pdb:1D6N|rcsb pdb:1HMP|rcsb pdb:1Z7G|go:"GO:0048813"(dendrite morphogenesis)|rcsb pdb:2VFA|rcsb pdb:3GEP|rcsb pdb:3GGC|rcsb pdb:3GGJ|rcsb pdb:4IJQ|rcsb pdb:4KN6|rcsb pdb:4RAB|rcsb pdb:4RAC|rcsb pdb:4RAD|rcsb pdb:4RAN|rcsb pdb:4RAO|rcsb pdb:4RAQ|rcsb pdb:5BRN|rcsb pdb:5BSK|rcsb pdb:5HIA|rcsb pdb:5W8V|rcsb pdb:6BNJ|reactome:R-HSA-74217	-	crc64:F3DBABE6AD3C7F3C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:etuSSgFGQOcgxPDexEXUqQg6H5s559292	rogid:w87Sv/qOAkHFqJm0vu0Ayqlz7TA9606	intact-crc:51C77F1175335BAB|rigid:amwpDhy02cE1/Ha06fNBQk+Smf8	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P53829	uniprotkb:Q7Z6G3-2	intact:EBI-28306|uniprotkb:D6W0Q5|ensemblfungi:YNL288W	intact:EBI-10172876|ensembl:ENSP00000457354|intact:EBI-14062040	psi-mi:caf40_yeast(display_long)|uniprotkb:YNL288W(locus name)|uniprotkb:N0540(orf name)|uniprotkb:40 kDa CCR4-associated factor(gene name synonym)|uniprotkb:CAF40(gene name)|psi-mi:CAF40(display_short)	psi-mi:q7z6g3-2(display_long)|uniprotkb:EFCBP2(gene name synonym)|uniprotkb:Neuronal calcium-binding protein 2(gene name synonym)|uniprotkb:Synaptotagmin-interacting protein 2(gene name synonym)|uniprotkb:NECAB2(gene name)|psi-mi:NECAB2(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550308|imex:IM-24995-3148	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014111.1|sgd:S000005232|dip:DIP-1995N|mint:P53829|ensemblfungi:YNL288W(gene)|ensemblfungi:YNL288W_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR007216(Cell differentiation, Rcd1-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:4CV5	ensembl:ENSG00000103154(gene)|ensembl:ENST00000565691(transcript)|uniprotkb:Q7Z6G3-2(isoform-parent)|intact:EBI-950070(isoform-parent)	-	crc64:F3DBABE6AD3C7F3C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:etuSSgFGQOcgxPDexEXUqQg6H5s559292	rogid:4S7oIx6h+mKzV3EPxqcfMNqaNko9606	intact-crc:EF4BA5618F2C53DA|rigid:IDVmdYPY6eAPOqTBtXgJKUh2BfQ	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q08379	uniprotkb:P53829	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	intact:EBI-28306|uniprotkb:D6W0Q5|ensemblfungi:YNL288W	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:caf40_yeast(display_long)|uniprotkb:YNL288W(locus name)|uniprotkb:N0540(orf name)|uniprotkb:40 kDa CCR4-associated factor(gene name synonym)|uniprotkb:CAF40(gene name)|psi-mi:CAF40(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550324|imex:IM-24995-3152	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N	refseq:NP_014111.1|sgd:S000005232|dip:DIP-1995N|mint:P53829|ensemblfungi:YNL288W(gene)|ensemblfungi:YNL288W_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR007216(Cell differentiation, Rcd1-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:4CV5	-	-	crc64:F3DBABE6AD3C7F3C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2017/05/26	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	rogid:etuSSgFGQOcgxPDexEXUqQg6H5s559292	intact-crc:F5173DC8C2A2C968|rigid:AIaiRZZYO7SNUfkmNR2PvjYLdGs	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P14373	uniprotkb:P53933	intact:EBI-719493|uniprotkb:A2BE15|uniprotkb:Q5RJA8|uniprotkb:Q5ST26|uniprotkb:Q6LA73|uniprotkb:Q6NXR9|uniprotkb:Q9BZY6|uniprotkb:Q9UJL3|ensembl:ENSP00000383555|ensembl:ENSP00000392787|ensembl:ENSP00000405229|ensembl:ENSP00000414793|ensembl:ENSP00000366404	intact:EBI-28798|uniprotkb:D6W186|ensemblfungi:YNL094W	psi-mi:tri27_human(display_long)|uniprotkb:TRIM27(gene name)|psi-mi:TRIM27(display_short)|uniprotkb:RNF76(gene name synonym)|uniprotkb:RFP(gene name synonym)|uniprotkb:Ret finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 27(gene name synonym)|uniprotkb:RING finger protein 76(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM27(gene name synonym)	psi-mi:app1_yeast(display_long)|uniprotkb:APP1(gene name)|psi-mi:APP1(display_short)|uniprotkb:Actin patch protein 1(gene name synonym)|uniprotkb:N2219(orf name)|uniprotkb:YNL094W(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550364|imex:IM-24995-3162	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006501.1|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0090281"(negative regulation of calcium ion import)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR020457|interpro:IPR035791|interpro:IPR043136|mint:P14373|reactome:R-HSA-3232142|reactome:R-HSA-9635465|reactome:R-HSA-8948751|ensembl:ENSG00000204713(gene)|ensembl:ENSG00000215641(gene)|ensembl:ENSG00000229006(gene)|ensembl:ENSG00000234495(gene)|ensembl:ENSG00000237071(gene)|ensembl:ENST00000377199(transcript)|ensembl:ENST00000400720(transcript)|ensembl:ENST00000431123(transcript)|ensembl:ENST00000435528(transcript)|ensembl:ENST00000437160(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001650"(fibrillar center)|go:"GO:0002820"(negative regulation of adaptive immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)	refseq:NP_014305.1|sgd:S000005038|dip:DIP-2006N|mint:P53933|ensemblfungi:YNL094W(gene)|ensemblfungi:YNL094W_mRNA(transcript)|go:"GO:0008195"(phosphatidate phosphatase activity)|go:"GO:0030479"(actin cortical patch)|go:"GO:0044255"(cellular lipid metabolic process)|interpro:IPR017210(Uncharacterised conserved protein UCP037464, actin patch protein 1)|interpro:IPR019236	-	-	crc64:B85C525548BA34BC	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:dsfH5OUghD8KSaTz1SFw9OYVTK49606	rogid:4ORrWVN2DOL+59LI2qWcKYYVfcE559292	intact-crc:CE04985D24DC4892|rigid:p9Jc60yOsm+pNpOb2wwtG/yIjMQ	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q08379	uniprotkb:P53933	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	intact:EBI-28798|uniprotkb:D6W186|ensemblfungi:YNL094W	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:app1_yeast(display_long)|uniprotkb:APP1(gene name)|psi-mi:APP1(display_short)|uniprotkb:Actin patch protein 1(gene name synonym)|uniprotkb:N2219(orf name)|uniprotkb:YNL094W(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550360|imex:IM-24995-3161	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N	refseq:NP_014305.1|sgd:S000005038|dip:DIP-2006N|mint:P53933|ensemblfungi:YNL094W(gene)|ensemblfungi:YNL094W_mRNA(transcript)|go:"GO:0008195"(phosphatidate phosphatase activity)|go:"GO:0030479"(actin cortical patch)|go:"GO:0044255"(cellular lipid metabolic process)|interpro:IPR017210(Uncharacterised conserved protein UCP037464, actin patch protein 1)|interpro:IPR019236	-	-	crc64:B85C525548BA34BC	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2017/05/26	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	rogid:4ORrWVN2DOL+59LI2qWcKYYVfcE559292	intact-crc:3F33AFF6B6D8CCE3|rigid:aZJHRGm/s29HLT82oyU7qLPpuxw	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P53933	uniprotkb:O95273	intact:EBI-28798|uniprotkb:D6W186|ensemblfungi:YNL094W	intact:EBI-748961|uniprotkb:A8K3Q0|uniprotkb:A8K3U2|uniprotkb:Q6ZQN9|uniprotkb:Q7Z519|uniprotkb:Q8NBS7|uniprotkb:Q8NBY2|uniprotkb:Q9NS19|uniprotkb:Q9NYH3|uniprotkb:Q9UHX9|ensembl:ENSP00000300213	psi-mi:app1_yeast(display_long)|uniprotkb:APP1(gene name)|psi-mi:APP1(display_short)|uniprotkb:Actin patch protein 1(gene name synonym)|uniprotkb:N2219(orf name)|uniprotkb:YNL094W(locus name)	psi-mi:ccdb1_human(display_long)|uniprotkb:Grap2 and cyclin-D-interacting protein(gene name synonym)|uniprotkb:Human homolog of Maid(gene name synonym)|uniprotkb:CCNDBP1(gene name)|psi-mi:CCNDBP1(display_short)|uniprotkb:DIP1(gene name synonym)|uniprotkb:GCIP(gene name synonym)|uniprotkb:HHM(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550356|imex:IM-24995-3160	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014305.1|sgd:S000005038|dip:DIP-2006N|mint:P53933|ensemblfungi:YNL094W(gene)|ensemblfungi:YNL094W_mRNA(transcript)|go:"GO:0008195"(phosphatidate phosphatase activity)|go:"GO:0030479"(actin cortical patch)|go:"GO:0044255"(cellular lipid metabolic process)|interpro:IPR017210(Uncharacterised conserved protein UCP037464, actin patch protein 1)|interpro:IPR019236	refseq:NP_036274.3|ensembl:ENSG00000166946(gene)|ensembl:ENST00000300213(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0016604"(nuclear body)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR026907|mint:O95273|rcsb pdb:3AY5	-	crc64:B85C525548BA34BC	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:4ORrWVN2DOL+59LI2qWcKYYVfcE559292	rogid:Vi9aoFc+Mov6P3X6KGmsTxXqxvM9606	intact-crc:13D0982D75BD229D|rigid:iivbEsNNyXz10fs2+QP+UQnmd68	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P53829	uniprotkb:P13196	intact:EBI-28306|uniprotkb:D6W0Q5|ensemblfungi:YNL288W	intact:EBI-3905054|ensembl:ENSP00000309259|ensembl:ENSP00000378416|ensembl:ENSP00000417719|ensembl:ENSP00000418779	psi-mi:caf40_yeast(display_long)|uniprotkb:YNL288W(locus name)|uniprotkb:N0540(orf name)|uniprotkb:40 kDa CCR4-associated factor(gene name synonym)|uniprotkb:CAF40(gene name)|psi-mi:CAF40(display_short)	psi-mi:hem1_human(display_long)|uniprotkb:ALAS1(gene name)|psi-mi:ALAS1(display_short)|uniprotkb:ALAS3(gene name synonym)|uniprotkb:ALASH(gene name synonym)|uniprotkb:5-aminolevulinic acid synthase 1(gene name synonym)|uniprotkb:Delta-ALA synthase 1(gene name synonym)|uniprotkb:Delta-aminolevulinate synthase 1(gene name synonym)|uniprotkb:OK/SW-cl.121(orf name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550336|imex:IM-24995-3155	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014111.1|sgd:S000005232|dip:DIP-1995N|mint:P53829|ensemblfungi:YNL288W(gene)|ensemblfungi:YNL288W_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR007216(Cell differentiation, Rcd1-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:4CV5	refseq:NP_001291372.1|refseq:NP_001291373.1|refseq:NP_000679.1|refseq:NP_954635.1|go:"GO:0006783"(heme biosynthetic process)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0042541"(hemoglobin biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0048821"(erythrocyte development)|ensembl:ENSG00000023330(gene)|ensembl:ENST00000310271(transcript)|ensembl:ENST00000394965(transcript)|ensembl:ENST00000469224(transcript)|ensembl:ENST00000484952(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0003870"(5-aminolevulinate synthase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|interpro:IPR001917(Aminotransferase, class-II, pyridoxal-phosphate binding site)|interpro:IPR004839(Aminotransferase, class I and II)|interpro:IPR010961(Tetrapyrrole biosynthesis, 5-aminolevulinic acid synthase)|interpro:IPR015118(5-aminolevulinate synthase presequence)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|mint:P13196|reactome:R-HSA-189451|reactome:R-HSA-1989781|reactome:R-HSA-2151201|go:"GO:0006782"(protoporphyrinogen IX biosynthetic process)	-	crc64:F3DBABE6AD3C7F3C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:etuSSgFGQOcgxPDexEXUqQg6H5s559292	rogid:HFjJ6zrRF9UYD7LMB6A3CcxcS7c9606	intact-crc:18DC5F524D29D83D|rigid:veJNsWE3nerBonQco5aUGJc24Cg	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:A0A024R4Q5	uniprotkb:P53900	intact:EBI-11527449	intact:EBI-13246|uniprotkb:D6W130|ensemblfungi:YNL153C	psi-mi:a0a024r4q5_human(display_long)|uniprotkb:hCG_20946(orf name)|uniprotkb:TFPT(gene name)|psi-mi:TFPT(display_short)	psi-mi:pfd4_yeast(display_long)|uniprotkb:GIM3(gene name)|psi-mi:GIM3(display_short)|uniprotkb:PFD4(gene name synonym)|uniprotkb:YNL153C(locus name)|uniprotkb:N1761(orf name)|uniprotkb:Genes involved in microtubule biogenesis protein 3(gene name synonym)|uniprotkb:Gim complex subunit 3(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550348|imex:IM-24995-3158	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_037474.1|interpro:IPR033555|go:"GO:0005654"(nucleoplasm)|go:"GO:0006915"(apoptotic process)	refseq:NP_014246.1|sgd:S000005097|mint:P53900|dip:DIP-3000N|ensemblfungi:YNL153C(gene)|ensemblfungi:YNL153C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:0015631"(tubulin binding)|go:"GO:0016272"(prefoldin complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0071629"(cytoplasm protein quality control by the ubiquitin-proteasome system)|interpro:IPR002777(Prefoldin beta-like)|interpro:IPR009053(Prefoldin)|interpro:IPR016661(Prefoldin, subunit 4)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:juI/3gZemjc0hnXDJ9J+bIQ9pBw9606	rogid:TdRDErsc5xwqaEqpI4SSCW0sCsg559292	intact-crc:DC8AD284458D72D5|rigid:1lexydUUIaNmP+up2nXxHIJg2AE	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P43365	uniprotkb:P53900	intact:EBI-749530|uniprotkb:Q9NSD3|intact:EBI-10178394|uniprotkb:Q6FHH8|ensembl:ENSP00000350592|ensembl:ENSP00000377447|ensembl:ENSP00000377478	intact:EBI-13246|uniprotkb:D6W130|ensemblfungi:YNL153C	psi-mi:magac_human(display_long)|uniprotkb:MAGE-12 antigen(gene name synonym)|uniprotkb:MAGE12F antigen(gene name synonym)|uniprotkb:Cancer/testis antigen 1.12(gene name synonym)|uniprotkb:MAGEA12(gene name)|psi-mi:MAGEA12(display_short)|uniprotkb:MAGE12(gene name synonym)	psi-mi:pfd4_yeast(display_long)|uniprotkb:GIM3(gene name)|psi-mi:GIM3(display_short)|uniprotkb:PFD4(gene name synonym)|uniprotkb:YNL153C(locus name)|uniprotkb:N1761(orf name)|uniprotkb:Genes involved in microtubule biogenesis protein 3(gene name synonym)|uniprotkb:Gim complex subunit 3(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550344|imex:IM-24995-3157	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001159858.1|refseq:NP_001159859.1|refseq:NP_005358.2|ensembl:ENSG00000213401(gene)|ensembl:ENST00000357916(transcript)|ensembl:ENST00000393869(transcript)|ensembl:ENST00000393900(transcript)|interpro:IPR002190(MAGE protein)|interpro:IPR021072|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899	refseq:NP_014246.1|sgd:S000005097|mint:P53900|dip:DIP-3000N|ensemblfungi:YNL153C(gene)|ensemblfungi:YNL153C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:0015631"(tubulin binding)|go:"GO:0016272"(prefoldin complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0071629"(cytoplasm protein quality control by the ubiquitin-proteasome system)|interpro:IPR002777(Prefoldin beta-like)|interpro:IPR009053(Prefoldin)|interpro:IPR016661(Prefoldin, subunit 4)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:3/Jxz2VsFOb67RWqWj3xbTrw3s49606	rogid:TdRDErsc5xwqaEqpI4SSCW0sCsg559292	intact-crc:6067031DDB5840CD|rigid:EPAg9IMHONr/O35Snf2Pkb3nT7k	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O95273	uniprotkb:P53833	intact:EBI-748961|uniprotkb:A8K3Q0|uniprotkb:A8K3U2|uniprotkb:Q6ZQN9|uniprotkb:Q7Z519|uniprotkb:Q8NBS7|uniprotkb:Q8NBY2|uniprotkb:Q9NS19|uniprotkb:Q9NYH3|uniprotkb:Q9UHX9|ensembl:ENSP00000300213	intact:EBI-13638|uniprotkb:D6W0R2|ensemblfungi:YNL282W	psi-mi:ccdb1_human(display_long)|uniprotkb:Grap2 and cyclin-D-interacting protein(gene name synonym)|uniprotkb:Human homolog of Maid(gene name synonym)|uniprotkb:CCNDBP1(gene name)|psi-mi:CCNDBP1(display_short)|uniprotkb:DIP1(gene name synonym)|uniprotkb:GCIP(gene name synonym)|uniprotkb:HHM(gene name synonym)	psi-mi:pop3_yeast(display_long)|uniprotkb:POP3(gene name)|psi-mi:POP3(display_short)|uniprotkb:YNL282W(locus name)|uniprotkb:N0586(orf name)|uniprotkb:RNA-processing protein POP3(gene name synonym)|uniprotkb:RNases MRP/P 22.6 kDa subunit(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550340|imex:IM-24995-3156	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_036274.3|ensembl:ENSG00000166946(gene)|ensembl:ENST00000300213(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0016604"(nuclear body)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR026907|mint:O95273|rcsb pdb:3AY5	ensemblfungi:YNL282W(gene)|refseq:NP_014117.1|sgd:S000005226|ensemblfungi:YNL282W_mRNA(transcript)|go:"GO:0000172"(ribonuclease MRP complex)|go:"GO:0000294"(nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay)|go:"GO:0005634"(nucleus)|go:"GO:0005655"(nucleolar ribonuclease P complex)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0008033"(tRNA processing)|go:"GO:0034965"(intronic box C/D RNA processing)|go:"GO:0090502"(RNA phosphodiester bond hydrolysis, endonucleolytic)|interpro:IPR013241(RNase P, subunit Pop3)|rcsb pdb:6AGB|rcsb pdb:6AH3|rcsb pdb:7C79|rcsb pdb:7C7A|mint:P53833|dip:DIP-4997N	-	-	crc64:5091EE590BDBCBEA	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:Vi9aoFc+Mov6P3X6KGmsTxXqxvM9606	rogid:t1z4FYhAJbd9swpeZ8/+rqxgKyk559292	intact-crc:EE0A373B4077A2E3|rigid:c3J1i2AwKwN4hlWp3i+QGshpy4g	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P43365	uniprotkb:P53923	intact:EBI-749530|uniprotkb:Q9NSD3|intact:EBI-10178394|uniprotkb:Q6FHH8|ensembl:ENSP00000350592|ensembl:ENSP00000377447|ensembl:ENSP00000377478	intact:EBI-28871|uniprotkb:B0KZW1|uniprotkb:B0L006|uniprotkb:Q66R25|uniprotkb:B0KZR6|uniprotkb:B0KZS5|uniprotkb:B0KZU3|uniprotkb:D6W163|ensemblfungi:YNL119W	psi-mi:magac_human(display_long)|uniprotkb:MAGE-12 antigen(gene name synonym)|uniprotkb:MAGE12F antigen(gene name synonym)|uniprotkb:Cancer/testis antigen 1.12(gene name synonym)|uniprotkb:MAGEA12(gene name)|psi-mi:MAGEA12(display_short)|uniprotkb:MAGE12(gene name synonym)	psi-mi:ctu2_yeast(display_long)|uniprotkb:TUC2(gene name synonym)|uniprotkb:N1913(orf name)|uniprotkb:YNL119W(locus name)|uniprotkb:NCS2(gene name)|psi-mi:NCS2(display_short)|uniprotkb:Thiolation of uridine in cytoplasmic tRNA protein 2(gene name synonym)|uniprotkb:CTU2(gene name synonym)|uniprotkb:Needs CLA4 to survive protein 2(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550352|imex:IM-24995-3159	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001159858.1|refseq:NP_001159859.1|refseq:NP_005358.2|ensembl:ENSG00000213401(gene)|ensembl:ENST00000357916(transcript)|ensembl:ENST00000393869(transcript)|ensembl:ENST00000393900(transcript)|interpro:IPR002190(MAGE protein)|interpro:IPR021072|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899	sgd:S000005063|refseq:NP_014280.3|dip:DIP-6649N|mint:P53923|ensemblfungi:YNL119W(gene)|ensemblfungi:YNL119W_mRNA(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0002143"(tRNA wobble position uridine thiolation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0016783"(sulfurtransferase activity)|go:"GO:0032447"(protein urmylation)|go:"GO:0034227"(tRNA thio-modification)|interpro:IPR019407	-	-	crc64:420FE465B982C43E	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:3/Jxz2VsFOb67RWqWj3xbTrw3s49606	rogid:TRbLQjCai4jNx+1IaH76vforp8c559292	intact-crc:A221EB24F52C7F2E|rigid:FIQmuXNX1WIeQSZFeh016yybyrw	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P40123	uniprotkb:P60010	intact:EBI-1051165|uniprotkb:Q6IAY2|uniprotkb:B2R5Y3|intact:EBI-11045298|uniprotkb:B7Z1C4|uniprotkb:B7Z214|ensembl:ENSP00000229922	intact:EBI-2169|uniprotkb:P02579|uniprotkb:Q9P3X6|uniprotkb:Q9P3X7|uniprotkb:D6VTJ1|ensemblfungi:YFL039C	psi-mi:cap2_human(display_long)|uniprotkb:CAP2(gene name)|psi-mi:CAP2(display_short)	psi-mi:act_yeast(display_long)|uniprotkb:ACT1(gene name)|psi-mi:ACT1(display_short)|uniprotkb:ABY1(gene name synonym)|uniprotkb:END7(gene name synonym)|uniprotkb:YFL039C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550404|imex:IM-24995-3172	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006357.1|ensembl:ENSG00000112186(gene)|ensembl:ENST00000229922(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007165"(signal transduction)|go:"GO:0007190"(activation of adenylate cyclase activity)|go:"GO:0008179"(adenylate cyclase binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0042802"(identical protein binding)|go:"GO:0045761"(regulation of adenylate cyclase activity)|interpro:IPR001837(Adenylate cyclase-associated CAP)|interpro:IPR006599(CARP motif)|interpro:IPR013912(Adenylate cyclase-associated CAP,  C-terminal)|interpro:IPR013992(Adenylate cyclase-associated CAP, N-terminal)|interpro:IPR016098(Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal)|interpro:IPR017901|interpro:IPR018106|interpro:IPR028417|interpro:IPR028418|interpro:IPR036222|interpro:IPR036223|reactome:R-HSA-428890|go:"GO:0005886"(plasma membrane)	refseq:NP_116614.1|sgd:S000001855|dip:DIP-310N|mint:P60010|ensemblfungi:YFL039C(gene)|ensemblfungi:YFL039C_mRNA(transcript)|go:"GO:0000011"(vacuole inheritance)|go:"GO:0000142"(cellular bud neck contractile ring)|go:"GO:0000812"(Swr1 complex)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005524"(ATP binding)|go:"GO:0005884"(actin filament)|go:"GO:0006281"(DNA repair)|go:"GO:0006897"(endocytosis)|go:"GO:0009306"(protein secretion)|go:"GO:0016573"(histone acetylation)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030476"(ascospore wall assembly)|go:"GO:0030479"(actin cortical patch)|go:"GO:0031011"(Ino80 complex)|go:"GO:0032432"(actin filament bundle)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:1902404"(mitotic actomyosin contractile ring contraction)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|rcsb pdb:1YAG|rcsb pdb:1YVN|rcsb pdb:5NBL|rcsb pdb:5NBM|rcsb pdb:5NBN|rcsb pdb:5Y81|reactome:R-SCE-114608|reactome:R-SCE-190873|reactome:R-SCE-196025|reactome:R-SCE-2029482|reactome:R-SCE-5626467|reactome:R-SCE-5663213|reactome:R-SCE-8856828|reactome:R-SCE-8980692|reactome:R-SCE-9013026	-	-	crc64:87AC19B0B0BC9E71	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:+B9t0sirXq7xJD3kZIlab7KBR9Y9606	rogid:yfgwiWq/Y0HviACqgjjUugpEKLw559292	intact-crc:F9082A503F8AC391|rigid:/eNgyaKHZ+vJNnJqoJIyS8i8+6s	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P56279	uniprotkb:P38251	intact:EBI-749995|uniprotkb:Q6IBK7|ensembl:ENSP00000385036|ensembl:ENSP00000450496|ensembl:ENSP00000450701|ensembl:ENSP00000451506	intact:EBI-15016|uniprotkb:D6VQ88|ensemblfungi:YBR087W	psi-mi:tcl1a_human(display_long)|uniprotkb:Protein p14 TCL1(gene name synonym)|uniprotkb:Oncogene TCL-1(gene name synonym)|uniprotkb:TCL1A(gene name)|psi-mi:TCL1A(display_short)|uniprotkb:TCL1(gene name synonym)	psi-mi:rfc5_yeast(display_long)|uniprotkb:RFC5(gene name)|psi-mi:RFC5(display_short)|uniprotkb:YBR087W(locus name)|uniprotkb:YBR0810(orf name)|uniprotkb:Activator 1 40 kDa subunit(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550400|imex:IM-24995-3171	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001092195.1|refseq:NP_068801.1|refseq:XP_016877165.1|refseq:XP_016877166.1|dip:DIP-60787N|ensembl:ENSG00000100721(gene)|ensembl:ENST00000402399(transcript)|ensembl:ENST00000554012(transcript)|ensembl:ENST00000555202(transcript)|ensembl:ENST00000556450(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010918"(positive regulation of mitochondrial membrane potential)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|interpro:IPR004832(TCL1/MTCP1)|interpro:IPR036672|rcsb pdb:1JSG	sgd:S000000291|refseq:NP_009644.3|go:"GO:0005634"(nucleus)|go:"GO:0005663"(DNA replication factor C complex)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006272"(leading strand elongation)|go:"GO:0006281"(DNA repair)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0031389"(Rad17 RFC-like complex)|go:"GO:0031390"(Ctf18 RFC-like complex)|go:"GO:0031391"(Elg1 RFC-like complex)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR027417|rcsb pdb:1SXJ|reactome:R-SCE-110312|reactome:R-SCE-110320|reactome:R-SCE-176187|reactome:R-SCE-5655862|reactome:R-SCE-5656121|reactome:R-SCE-5656169|reactome:R-SCE-5696397|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-69091|go:"GO:0005524"(ATP binding)|ensemblfungi:YBR087W(gene)|ensemblfungi:YBR087W_mRNA(transcript)|go:"GO:0003677"(DNA binding)|dip:DIP-2531N|mint:P38251	-	-	crc64:4CD403AF2AFA2961	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:c3GIYkYNb+wWlxn59oU2vpvbfhI9606	rogid:+ZnpxdiC5XBOQaSnExK98LVvFvA559292	intact-crc:05C10C2762519F91|rigid:LA6kcR6908IRGzzUl0yjuxi7oxQ	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P56279	uniprotkb:P32502	intact:EBI-749995|uniprotkb:Q6IBK7|ensembl:ENSP00000385036|ensembl:ENSP00000450496|ensembl:ENSP00000450701|ensembl:ENSP00000451506	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:tcl1a_human(display_long)|uniprotkb:Protein p14 TCL1(gene name synonym)|uniprotkb:Oncogene TCL-1(gene name synonym)|uniprotkb:TCL1A(gene name)|psi-mi:TCL1A(display_short)|uniprotkb:TCL1(gene name synonym)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550396|imex:IM-24995-3170	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001092195.1|refseq:NP_068801.1|refseq:XP_016877165.1|refseq:XP_016877166.1|dip:DIP-60787N|ensembl:ENSG00000100721(gene)|ensembl:ENST00000402399(transcript)|ensembl:ENST00000554012(transcript)|ensembl:ENST00000555202(transcript)|ensembl:ENST00000556450(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010918"(positive regulation of mitochondrial membrane potential)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|interpro:IPR004832(TCL1/MTCP1)|interpro:IPR036672|rcsb pdb:1JSG	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731	-	-	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:c3GIYkYNb+wWlxn59oU2vpvbfhI9606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:8B0F58F3A67D3AF1|rigid:CIW6CN8FzBdRzFyhwkSFg435ROc	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P40560	uniprotkb:P56279	intact:EBI-24911|uniprotkb:D6VVT0|ensemblfungi:YIL001W	intact:EBI-749995|uniprotkb:Q6IBK7|ensembl:ENSP00000385036|ensembl:ENSP00000450496|ensembl:ENSP00000450701|ensembl:ENSP00000451506	psi-mi:yia1_yeast(display_long)|uniprotkb:YIA1W(orf name)|uniprotkb:YIL001W(locus name)	psi-mi:tcl1a_human(display_long)|uniprotkb:Protein p14 TCL1(gene name synonym)|uniprotkb:Oncogene TCL-1(gene name synonym)|uniprotkb:TCL1A(gene name)|psi-mi:TCL1A(display_short)|uniprotkb:TCL1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550392|imex:IM-24995-3169	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000001263|refseq:NP_012265.3|dip:DIP-1375N|ensemblfungi:YIL001W(gene)|ensemblfungi:YIL001W_mRNA(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0005737"(cytoplasm)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR036770|interpro:IPR044515	refseq:NP_001092195.1|refseq:NP_068801.1|refseq:XP_016877165.1|refseq:XP_016877166.1|dip:DIP-60787N|ensembl:ENSG00000100721(gene)|ensembl:ENST00000402399(transcript)|ensembl:ENST00000554012(transcript)|ensembl:ENST00000555202(transcript)|ensembl:ENST00000556450(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010918"(positive regulation of mitochondrial membrane potential)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|interpro:IPR004832(TCL1/MTCP1)|interpro:IPR036672|rcsb pdb:1JSG	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:IOv6oxjYJ3W/jLnmIcM03RDQ8Ww559292	rogid:c3GIYkYNb+wWlxn59oU2vpvbfhI9606	intact-crc:5F3824A9247C6EAD|rigid:QdJLKH/PLO6O2Zc3fR0ilnWuV+8	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P53992	uniprotkb:P53829	intact:EBI-81134|uniprotkb:Q8WV25|ensembl:ENSP00000321845|ensembl:ENSP00000343405|uniprotkb:B4DZT4	intact:EBI-28306|uniprotkb:D6W0Q5|ensemblfungi:YNL288W	psi-mi:sc24c_human(display_long)|uniprotkb:SEC24C(gene name)|psi-mi:SEC24C(display_short)|uniprotkb:KIAA0079(gene name synonym)|uniprotkb:SEC24-related protein C(gene name synonym)	psi-mi:caf40_yeast(display_long)|uniprotkb:YNL288W(locus name)|uniprotkb:N0540(orf name)|uniprotkb:40 kDa CCR4-associated factor(gene name synonym)|uniprotkb:CAF40(gene name)|psi-mi:CAF40(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550368|imex:IM-24995-3163	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0090110"(COPII-coated vesicle cargo loading)|go:"GO:0070971"(endoplasmic reticulum exit site)|interpro:IPR006895(Zinc finger, Sec23/Sec24-type)|interpro:IPR006896(Sec23/Sec24 trunk region)|interpro:IPR006900(Sec23/Sec24 helical region)|interpro:IPR007123(Gelsolin region)|interpro:IPR012990(Sec23/Sec24 beta-sandwich)|interpro:IPR029006|interpro:IPR036174|interpro:IPR036175|interpro:IPR036180|interpro:IPR036465|interpro:IPR041742|mint:P53992|rcsb pdb:3EH2|rcsb pdb:6PU1|reactome:R-HSA-1655829|reactome:R-HSA-204005|reactome:R-HSA-2132295|reactome:R-HSA-983170|reactome:R-HSA-5694530|ensembl:ENSG00000176986(gene)|ensembl:ENST00000339365(transcript)|ensembl:ENST00000345254(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0008270"(zinc ion binding)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0030127"(COPII vesicle coat)|refseq:NP_004913.2|refseq:NP_940999.1|dip:DIP-30981N	refseq:NP_014111.1|sgd:S000005232|dip:DIP-1995N|mint:P53829|ensemblfungi:YNL288W(gene)|ensemblfungi:YNL288W_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR007216(Cell differentiation, Rcd1-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:4CV5	-	-	crc64:F3DBABE6AD3C7F3C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:kOKJkIWFOlIpRFLj5JshAGqAg6s9606	rogid:etuSSgFGQOcgxPDexEXUqQg6H5s559292	intact-crc:6BE1AFC304725A22|rigid:P4fg5s32kxj2U9SlU+cnA9lU0nE	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P54791	uniprotkb:Q08379	intact:EBI-12580|uniprotkb:D6W4G3|ensemblfungi:YPR162C	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	psi-mi:orc4_yeast(display_long)|uniprotkb:ORC4(gene name)|psi-mi:ORC4(display_short)|uniprotkb:YPR162C(locus name)|uniprotkb:P9325.5(orf name)|uniprotkb:Origin recognition complex 56 kDa subunit(gene name synonym)	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550384|imex:IM-24995-3167	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YPR162C(gene)|ensemblfungi:YPR162C_mRNA(transcript)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031261"(DNA replication preinitiation complex)|interpro:IPR016527(Origin recognition complex, subunit 4)|interpro:IPR027417|interpro:IPR032705|rcsb pdb:5V8F|rcsb pdb:5ZR1|rcsb pdb:6RQC|rcsb pdb:6WGC|rcsb pdb:6WGG|rcsb pdb:6WGI|rcsb pdb:7MCA|reactome:R-SCE-68616|reactome:R-SCE-68962|reactome:R-SCE-68949|refseq:NP_015488.1|sgd:S000006366|dip:DIP-2287N|mint:P54791	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N	-	crc64:ACF064F2C633F13F	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2017/05/26	rogid:kJZ5UJVsvZNFQEkBR9tmPOJ+Iv8559292	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	intact-crc:9B340FE4B01BF9EA|rigid:DSx17Ve2DO16uWh9vlHWt53cQjM	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O14641	uniprotkb:P54787	intact:EBI-740850|ensembl:ENSP00000005340|uniprotkb:Q53XM0|uniprotkb:D3DTN3	intact:EBI-20495|uniprotkb:D6W0I8|ensemblfungi:YML097C	psi-mi:dvl2_human(display_long)|uniprotkb:DSH homolog 2(gene name synonym)|uniprotkb:DVL2(gene name)|psi-mi:DVL2(display_short)	psi-mi:vps9_yeast(display_long)|uniprotkb:VPS9(gene name)|psi-mi:VPS9(display_short)|uniprotkb:Vacuolar protein-targeting protein 9(gene name synonym)|uniprotkb:VPT9(gene name synonym)|uniprotkb:YML097C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550380|imex:IM-24995-3166	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004413.1|ensembl:ENSG00000004975(gene)|ensembl:ENST00000005340(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005109"(frizzled binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0007507"(heart development)|go:"GO:0016235"(aggresome)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044340"(canonical Wnt signaling pathway involved in regulation of cell proliferation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0150012"(positive regulation of neuron projection arborization)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008341(Dishevelled-2 region)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:O14641|rcsb pdb:2REY|rcsb pdb:3CBX|rcsb pdb:3CBY|rcsb pdb:3CBZ|rcsb pdb:3CC0|rcsb pdb:4WIP|rcsb pdb:5LNP|rcsb pdb:5SUY|rcsb pdb:5SUZ|rcsb pdb:6IW3|rcsb pdb:6JCK|reactome:R-HSA-201681|reactome:R-HSA-201688|reactome:R-HSA-2028269|reactome:R-HSA-4086400|reactome:R-HSA-4608870|reactome:R-HSA-4641258|reactome:R-HSA-4641262|reactome:R-HSA-5099900|reactome:R-HSA-5368598|reactome:R-HSA-5663220|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9673324|ensembl:ENSP00000005340|dip:DIP-34433N	refseq:NP_013612.1|sgd:S000004563|ensemblfungi:YML097C(gene)|ensemblfungi:YML097C_mRNA(transcript)|go:"GO:0000011"(vacuole inheritance)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR009060(UBA-like)|interpro:IPR037191|interpro:IPR041545|interpro:IPR041804|rcsb pdb:1MN3|rcsb pdb:1P3Q|reactome:R-SCE-8876198|reactome:R-SCE-8856828|dip:DIP-4526N|mint:P54787	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:2Vdc8oRnT4Mz/j+EXQXrL3AszOc9606	rogid:ogXRiOOp698mlPdAiFidYakMtI4559292	intact-crc:F5272B16C6E35EB0|rigid:6vhH6nB5Hy1JS8ihA9K04mjJlK4	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P54619	uniprotkb:P06782	intact:EBI-1181439|ensembl:ENSP00000447433|uniprotkb:B4DDT7|uniprotkb:Q8N7V9	intact:EBI-17516|uniprotkb:D6VTA0|ensemblfungi:YDR477W	psi-mi:aakg1_human(display_long)|uniprotkb:PRKAG1(gene name)|psi-mi:PRKAG1(display_short)	psi-mi:snf1_yeast(display_long)|uniprotkb:SNF1(gene name)|psi-mi:SNF1(display_short)|uniprotkb:CAT1(gene name synonym)|uniprotkb:CCR1(gene name synonym)|uniprotkb:GLC2(gene name synonym)|uniprotkb:PAS14(gene name synonym)|uniprotkb:Sucrose nonfermentating protein 1(gene name synonym)|uniprotkb:D8035.20(orf name)|uniprotkb:YDR477W(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550376|imex:IM-24995-3165	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001193638.1|refseq:NP_001193639.1|refseq:NP_002724.1|refseq:XP_011536864.1|reactome:R-HSA-9619483|reactome:R-HSA-9613354|ensembl:ENSG00000181929(gene)|ensembl:ENST00000548065(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004691"(cAMP-dependent protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006110"(regulation of glycolytic process)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008603"(cAMP-dependent protein kinase regulator activity)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016208"(AMP binding)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0043531"(ADP binding)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051170"(import into nucleus)|go:"GO:0071900"(regulation of protein serine/threonine kinase activity)|interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR039166|mint:P54619|rcsb pdb:2UV4|rcsb pdb:2UV5|rcsb pdb:2UV6|rcsb pdb:2UV7|rcsb pdb:4CFE|rcsb pdb:4CFF|rcsb pdb:4RER|rcsb pdb:4REW|rcsb pdb:4ZHX|rcsb pdb:5EZV|rcsb pdb:5ISO|rcsb pdb:6B1U|rcsb pdb:6B2E|rcsb pdb:6C9F|rcsb pdb:6C9G|rcsb pdb:6C9H|rcsb pdb:6C9J|reactome:R-HSA-1445148|reactome:R-HSA-1632852|reactome:R-HSA-2151209|reactome:R-HSA-380972|reactome:R-HSA-5628897|reactome:R-HSA-6804756|refseq:XP_006719562.1|dip:DIP-39974N	refseq:NP_010765.3|sgd:S000002885|ensemblfungi:YDR477W(gene)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0071940"(fungal-type cell wall assembly)|go:"GO:0090606"(single-species surface biofilm formation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900436"(positive regulation of filamentous growth of a population of unicellular organisms in response to starvation)|go:"GO:2000222"(positive regulation of pseudohyphal growth)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013896(Ubiquitin-associated region 2)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR028375|interpro:IPR032270|rcsb pdb:2FH9|rcsb pdb:2QLV|rcsb pdb:3DAE|rcsb pdb:3HYH|rcsb pdb:3MN3|rcsb pdb:3T4N|rcsb pdb:3TDH|rcsb pdb:3TE5|reactome:R-SCE-1632852|reactome:R-SCE-163680|reactome:R-SCE-200425|reactome:R-SCE-380972|ensemblfungi:YDR477W_mRNA(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000144"(cellular bud neck septin ring)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004679"(AMP-activated protein kinase activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005641"(nuclear envelope lumen)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0007155"(cell adhesion)|go:"GO:0016239"(positive regulation of macroautophagy)|dip:DIP-18N|mint:P06782	-	-	crc64:F5C63565C986C4E3	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:JNBzPdCbcgr37RKb2sk6yVL+7649606	rogid:O/SAW1kJE3fpoXPHGLG01i9RePs559292	intact-crc:153E65C403D69C5D|rigid:IgHiISYAnTxvf0XuRQBFtsbYGuE	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P20081	uniprotkb:P53992	intact:EBI-6961|uniprotkb:D6W147|ensemblfungi:YNL135C	intact:EBI-81134|uniprotkb:Q8WV25|ensembl:ENSP00000321845|ensembl:ENSP00000343405|uniprotkb:B4DZT4	psi-mi:fkbp_yeast(display_long)|uniprotkb:RBP1(gene name synonym)|uniprotkb:N1213(orf name)|uniprotkb:N1845(orf name)|uniprotkb:YNL135C(locus name)|uniprotkb:FPR1(gene name)|psi-mi:FPR1(display_short)|uniprotkb:FKB1(gene name synonym)|uniprotkb:Peptidyl-prolyl cis-trans isomerase(gene name synonym)|uniprotkb:Rapamycin-binding protein(gene name synonym)	psi-mi:sc24c_human(display_long)|uniprotkb:SEC24C(gene name)|psi-mi:SEC24C(display_short)|uniprotkb:KIAA0079(gene name synonym)|uniprotkb:SEC24-related protein C(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550372|imex:IM-24995-3164	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014264.1|sgd:S000005079|dip:DIP-1263N|mint:P20081|ensemblfungi:YNL135C(gene)|ensemblfungi:YNL135C_mRNA(transcript)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005527"(macrolide binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006325"(chromatin organization)|go:"GO:0006457"(protein folding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:1901710"(regulation of homoserine biosynthetic process)|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)|rcsb pdb:1YAT	go:"GO:0090110"(COPII-coated vesicle cargo loading)|go:"GO:0070971"(endoplasmic reticulum exit site)|interpro:IPR006895(Zinc finger, Sec23/Sec24-type)|interpro:IPR006896(Sec23/Sec24 trunk region)|interpro:IPR006900(Sec23/Sec24 helical region)|interpro:IPR007123(Gelsolin region)|interpro:IPR012990(Sec23/Sec24 beta-sandwich)|interpro:IPR029006|interpro:IPR036174|interpro:IPR036175|interpro:IPR036180|interpro:IPR036465|interpro:IPR041742|mint:P53992|rcsb pdb:3EH2|rcsb pdb:6PU1|reactome:R-HSA-1655829|reactome:R-HSA-204005|reactome:R-HSA-2132295|reactome:R-HSA-983170|reactome:R-HSA-5694530|ensembl:ENSG00000176986(gene)|ensembl:ENST00000339365(transcript)|ensembl:ENST00000345254(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0008270"(zinc ion binding)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0030127"(COPII vesicle coat)|refseq:NP_004913.2|refseq:NP_940999.1|dip:DIP-30981N	-	crc64:65C134830D300C06	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:8afvGSk+mPghtqkVoWd2rHJXXhQ559292	rogid:kOKJkIWFOlIpRFLj5JshAGqAg6s9606	intact-crc:27B29FF7610ABF53|rigid:Zf31zF/KLpq8P12LqD+1kWSQAIY	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P55212	uniprotkb:P32502	intact:EBI-718729|uniprotkb:Q9BQE7|ensembl:ENSP00000265164	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:casp6_human(display_long)|uniprotkb:Apoptotic protease Mch-2(gene name synonym)|uniprotkb:CASP6(gene name)|psi-mi:CASP6(display_short)|uniprotkb:MCH2(gene name synonym)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550388|imex:IM-24995-3168	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001217.2|refseq:NP_116787.1|rcsb pdb:3K7E|rcsb pdb:3NKF|rcsb pdb:3NR2|rcsb pdb:3OD5|rcsb pdb:3P45|rcsb pdb:3P4U|rcsb pdb:3QNW|rcsb pdb:3S70|rcsb pdb:3S8E|rcsb pdb:3V6L|rcsb pdb:3V6M|rcsb pdb:4EJF|rcsb pdb:4FXO|rcsb pdb:4HVA|rcsb pdb:4IYR|rcsb pdb:4N5D|rcsb pdb:4N6G|rcsb pdb:4N7J|rcsb pdb:4N7M|rcsb pdb:4NBK|rcsb pdb:4NBL|rcsb pdb:4NBN|rcsb pdb:6DEU|rcsb pdb:6DEV|reactome:R-HSA-111465|reactome:R-HSA-264870|reactome:R-HSA-352238|reactome:R-HSA-6803207|ensembl:ENSG00000138794(gene)|ensembl:ENST00000265164(transcript)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006508"(proteolysis)|go:"GO:0006915"(apoptotic process)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0072734"(cellular response to staurosporine)|go:"GO:0097153"(cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0097200"(cysteine-type endopeptidase activity involved in execution phase of apoptosis)|interpro:IPR001309(Peptidase C14, ICE, catalytic subunit p20)|interpro:IPR002138(Peptidase C14, caspase non-catalytic subunit p10)|interpro:IPR002398(Peptidase C14, caspase precursor p45)|interpro:IPR015917(Peptidase C14, caspase precursor p45, core)|interpro:IPR016129(Peptidase C14, ICE, catalytic subunit p20, active site)|interpro:IPR029030|interpro:IPR033139|interpro:IPR037554|mint:P55212|rcsb pdb:1MI9|rcsb pdb:2WDP|dip:DIP-44649N	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731	-	-	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:x335dTT6omZBrEGs7jzxOjUWaNM9606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:7295DE61DBCC0C0D|rigid:dfY8xgiMbt4rskxNsX0THjbpt1I	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P38340	uniprotkb:P61289	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-355546|uniprotkb:O35563|uniprotkb:P97373|uniprotkb:Q12920|uniprotkb:Q13172|uniprotkb:Q9BQD9|uniprotkb:A8K9A3|ensembl:ENSP00000466794	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:psme3_human(display_long)|uniprotkb:PSME3(gene name)|psi-mi:PSME3(display_short)|uniprotkb:Proteasome activator 28 subunit gamma(gene name synonym)|uniprotkb:Activator of multicatalytic protease subunit 3(gene name synonym)|uniprotkb:11S regulator complex subunit gamma(gene name synonym)|uniprotkb:Ki nuclear autoantigen(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550440|imex:IM-24995-3181	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F	refseq:NP_005780.2|refseq:NP_789839.1|ensembl:ENSG00000131467(gene)|ensembl:ENST00000590720(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0008537"(proteasome activator complex)|go:"GO:0010950"(positive regulation of endopeptidase activity)|go:"GO:0016020"(membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0061133"(endopeptidase activator activity)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0097371"(MDM2/MDM4 family protein binding)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR003185(Proteasome activator pa28, REG alpha subunit)|interpro:IPR003186(Proteasome activator pa28, REG beta subunit)|interpro:IPR009077(Proteasome activator pa28, REG alpha/beta subunit)|interpro:IPR036252|interpro:IPR036996|interpro:IPR036997|mint:P61289|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168	-	crc64:66699F37B0013088	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:6EQY2Kj3Juf++m4eBDzPWMgbC2k9606	intact-crc:05ECB764BBD88E7D|rigid:7U4wu5I6Bsc+tS2OG9Fyn5XNSG8	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P61289	uniprotkb:P46682	intact:EBI-355546|uniprotkb:O35563|uniprotkb:P97373|uniprotkb:Q12920|uniprotkb:Q13172|uniprotkb:Q9BQD9|uniprotkb:A8K9A3|ensembl:ENSP00000466794	intact:EBI-2213|uniprotkb:D6VV40|ensemblfungi:YGR261C	psi-mi:psme3_human(display_long)|uniprotkb:PSME3(gene name)|psi-mi:PSME3(display_short)|uniprotkb:Proteasome activator 28 subunit gamma(gene name synonym)|uniprotkb:Activator of multicatalytic protease subunit 3(gene name synonym)|uniprotkb:11S regulator complex subunit gamma(gene name synonym)|uniprotkb:Ki nuclear autoantigen(gene name synonym)	psi-mi:ap3b_yeast(display_long)|uniprotkb:APL6(gene name)|psi-mi:APL6(display_short)|uniprotkb:YKS5(gene name synonym)|uniprotkb:YGR261C(locus name)|uniprotkb:G9331(orf name)|uniprotkb:Beta-3-adaptin(gene name synonym)|uniprotkb:Clathrin assembly protein complex 3 beta large chain(gene name synonym)|uniprotkb:Clathrin assembly protein large beta chain(gene name synonym)|uniprotkb:Adaptor-related protein complex 3 subunit beta(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550436|imex:IM-24995-3180	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005780.2|refseq:NP_789839.1|ensembl:ENSG00000131467(gene)|ensembl:ENST00000590720(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0008537"(proteasome activator complex)|go:"GO:0010950"(positive regulation of endopeptidase activity)|go:"GO:0016020"(membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0061133"(endopeptidase activator activity)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0097371"(MDM2/MDM4 family protein binding)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR003185(Proteasome activator pa28, REG alpha subunit)|interpro:IPR003186(Proteasome activator pa28, REG beta subunit)|interpro:IPR009077(Proteasome activator pa28, REG alpha/beta subunit)|interpro:IPR036252|interpro:IPR036996|interpro:IPR036997|mint:P61289|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168	sgd:S000003493|refseq:NP_011777.3|ensemblfungi:YGR261C(gene)|ensemblfungi:YGR261C_mRNA(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030123"(AP-3 adaptor complex)|go:"GO:0030665"(clathrin-coated vesicle membrane)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026739|interpro:IPR026740|dip:DIP-2684N|mint:P46682	-	-	crc64:475DA3A4F6E68E97	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:6EQY2Kj3Juf++m4eBDzPWMgbC2k9606	rogid:J+pCwMtq9Jhj24BeTVg7XpCHmKE559292	intact-crc:49DC0EB0AAE3585B|rigid:DbAIVQbJkO3NIpxeEDw6z/iVMcw	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P53278	uniprotkb:P61289	intact:EBI-23314|uniprotkb:D6VUR2|ensemblfungi:YGR130C	intact:EBI-355546|uniprotkb:O35563|uniprotkb:P97373|uniprotkb:Q12920|uniprotkb:Q13172|uniprotkb:Q9BQD9|uniprotkb:A8K9A3|ensembl:ENSP00000466794	psi-mi:yg3a_yeast(display_long)|uniprotkb:YGR130C(locus name)	psi-mi:psme3_human(display_long)|uniprotkb:PSME3(gene name)|psi-mi:PSME3(display_short)|uniprotkb:Proteasome activator 28 subunit gamma(gene name synonym)|uniprotkb:Activator of multicatalytic protease subunit 3(gene name synonym)|uniprotkb:11S regulator complex subunit gamma(gene name synonym)|uniprotkb:Ki nuclear autoantigen(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550432|imex:IM-24995-3179	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011646.1|sgd:S000003362|dip:DIP-3006N|mint:P53278|ensemblfungi:YGR130C(gene)|ensemblfungi:YGR130C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0032126"(eisosome)	refseq:NP_005780.2|refseq:NP_789839.1|ensembl:ENSG00000131467(gene)|ensembl:ENST00000590720(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0008537"(proteasome activator complex)|go:"GO:0010950"(positive regulation of endopeptidase activity)|go:"GO:0016020"(membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0061133"(endopeptidase activator activity)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0097371"(MDM2/MDM4 family protein binding)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR003185(Proteasome activator pa28, REG alpha subunit)|interpro:IPR003186(Proteasome activator pa28, REG beta subunit)|interpro:IPR009077(Proteasome activator pa28, REG alpha/beta subunit)|interpro:IPR036252|interpro:IPR036996|interpro:IPR036997|mint:P61289|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168	-	crc64:D482327C9274C026	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:iTa1C3VXvI8QteEEgkfjQDp9gvY559292	rogid:6EQY2Kj3Juf++m4eBDzPWMgbC2k9606	intact-crc:D4F0D09289098ECA|rigid:DC1j0vegFjPWtc6Trafxcf34fGE	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P32502	uniprotkb:P61289	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	intact:EBI-355546|uniprotkb:O35563|uniprotkb:P97373|uniprotkb:Q12920|uniprotkb:Q13172|uniprotkb:Q9BQD9|uniprotkb:A8K9A3|ensembl:ENSP00000466794	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:psme3_human(display_long)|uniprotkb:PSME3(gene name)|psi-mi:PSME3(display_short)|uniprotkb:Proteasome activator 28 subunit gamma(gene name synonym)|uniprotkb:Activator of multicatalytic protease subunit 3(gene name synonym)|uniprotkb:11S regulator complex subunit gamma(gene name synonym)|uniprotkb:Ki nuclear autoantigen(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550428|imex:IM-24995-3178	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731	refseq:NP_005780.2|refseq:NP_789839.1|ensembl:ENSG00000131467(gene)|ensembl:ENST00000590720(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0008537"(proteasome activator complex)|go:"GO:0010950"(positive regulation of endopeptidase activity)|go:"GO:0016020"(membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0061133"(endopeptidase activator activity)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0097371"(MDM2/MDM4 family protein binding)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR003185(Proteasome activator pa28, REG alpha subunit)|interpro:IPR003186(Proteasome activator pa28, REG beta subunit)|interpro:IPR009077(Proteasome activator pa28, REG alpha/beta subunit)|interpro:IPR036252|interpro:IPR036996|interpro:IPR036997|mint:P61289|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168	-	crc64:A5409FAF1594854C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	rogid:6EQY2Kj3Juf++m4eBDzPWMgbC2k9606	intact-crc:4D4C99E8565D0AA2|rigid:QW7H1v5iA2hK7wS1iphn9qRlhQg	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P60709	uniprotkb:P46680	intact:EBI-353944|uniprotkb:P02570|uniprotkb:P70514|uniprotkb:P99021|uniprotkb:Q11211|uniprotkb:Q64316|uniprotkb:Q75MN2|uniprotkb:Q96B34|uniprotkb:Q96HG5|ensembl:ENSP00000494269|ensembl:ENSP00000494750|ensembl:ENSP00000495995|ensembl:ENSP00000501862|ensembl:ENSP00000502821	intact:EBI-2406|uniprotkb:D6VZR5|ensemblfungi:YMR092C	psi-mi:actb_human(display_long)|uniprotkb:ACTB(gene name)|psi-mi:ACTB(display_short)|uniprotkb:Beta-actin(gene name synonym)	psi-mi:aip1_yeast(display_long)|uniprotkb:AIP1(gene name)|psi-mi:AIP1(display_short)|uniprotkb:YM9582.17C(orf name)|uniprotkb:YMR092C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550408|imex:IM-24995-3173	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001092.1|ensembl:ENSG00000075624(gene)|ensembl:ENST00000493945(transcript)|ensembl:ENST00000642480(transcript)|ensembl:ENST00000646664(transcript)|ensembl:ENST00000674681(transcript)|ensembl:ENST00000675515(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000785"(chromatin)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0001895"(retina homeostasis)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007409"(axonogenesis)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019894"(kinesin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0022898"(regulation of transmembrane transporter activity)|go:"GO:0030027"(lamellipodium)|go:"GO:0030424"(axon)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0030957"(Tat protein binding)|go:"GO:0031982"(vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034333"(adherens junction assembly)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043044"|go:"GO:0043296"(apical junction complex)|go:"GO:0044305"(calyx of Held)|go:"GO:0045176"(apical protein localization)|go:"GO:0045202"(synapse)|go:"GO:0048156"(tau protein binding)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048870"(cell motility)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051621"(regulation of norepinephrine uptake)|go:"GO:0051623"(positive regulation of norepinephrine uptake)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070160"(tight junction)|go:"GO:0070527"(platelet aggregation)|reactome:R-HSA-4420097|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0072562"(blood microparticle)|go:"GO:0072749"(cellular response to cytochalasin B)|go:"GO:0097433"(dense body)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098973"(structural constituent of postsynaptic actin cytoskeleton)|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0150111"(regulation of transepithelial transport)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P60709|rcsb pdb:3BYH|rcsb pdb:3D2U|rcsb pdb:3J82|rcsb pdb:3LUE|rcsb pdb:6ANU|rcsb pdb:6ICT|rcsb pdb:6ICV|rcsb pdb:6LTJ|rcsb pdb:6MBJ|rcsb pdb:6MBK|rcsb pdb:6MBL|rcsb pdb:6NBW|rcsb pdb:6OX0|rcsb pdb:6OX1|rcsb pdb:6OX2|rcsb pdb:6OX3|rcsb pdb:6OX4|rcsb pdb:6OX5|rcsb pdb:6V62|rcsb pdb:6V63|rcsb pdb:6WK1|rcsb pdb:6WK2|rcsb pdb:7AS4|reactome:R-HSA-1445148|reactome:R-HSA-190873|reactome:R-HSA-196025|reactome:R-HSA-2029482|reactome:R-HSA-3214847|reactome:R-HSA-389957|reactome:R-HSA-390450|reactome:R-HSA-3928662|reactome:R-HSA-3928665|reactome:R-HSA-418990|reactome:R-HSA-437239|reactome:R-HSA-446353|reactome:R-HSA-5250924|reactome:R-HSA-5626467|reactome:R-HSA-5663213|reactome:R-HSA-5663220|reactome:R-HSA-5674135|reactome:R-HSA-5689603|reactome:R-HSA-5696394|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8856828|reactome:R-HSA-9035034|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9662360|reactome:R-HSA-9662361|reactome:R-HSA-9664422|reactome:R-HSA-983231|reactome:R-HSA-445095|dip:DIP-29686N	refseq:NP_013810.1|sgd:S000004698|reactome:R-SCE-114608|dip:DIP-890N|ensemblfungi:YMR092C(gene)|ensemblfungi:YMR092C_mRNA(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005884"(actin filament)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030479"(actin cortical patch)|go:"GO:0030836"(positive regulation of actin filament depolymerization)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032466"(negative regulation of cytokinesis)|go:"GO:0043332"(mating projection tip)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|rcsb pdb:1PGU|rcsb pdb:1PI6	-	-	crc64:B8340BF68DD08257	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:Hoge1B8Pn56kvbNTpkSLsQuHwRc9606	rogid:TwLC/U+xqc7crYws+782F2f1rEo559292	intact-crc:719E2DDEC5198757|rigid:QcyuVysqGGcjywTrYed9rsrPJ28	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P38340	uniprotkb:P60891	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-749195|uniprotkb:P09329|uniprotkb:B2R6T7|uniprotkb:B1ALA8|uniprotkb:B4DNL6|uniprotkb:D3DUX6|ensembl:ENSP00000361512	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:prps1_human(display_long)|uniprotkb:Phosphoribosyl pyrophosphate synthase I(gene name synonym)|uniprotkb:PRPS1(gene name)|psi-mi:PRPS1(display_short)|uniprotkb:PPRibP(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550420|imex:IM-24995-3176	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F	refseq:NP_001191331.1|refseq:NP_002755.1|ensembl:ENSG00000147224(gene)|ensembl:ENST00000372435(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0002189"(ribose phosphate diphosphokinase complex)|go:"GO:0004749"(ribose phosphate diphosphokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006015"(5-phosphoribose 1-diphosphate biosynthetic process)|go:"GO:0006164"(purine nucleotide biosynthetic process)|go:"GO:0006221"(pyrimidine nucleotide biosynthetic process)|go:"GO:0007399"(nervous system development)|go:"GO:0009116"(nucleoside metabolic process)|go:"GO:0009156"(ribonucleoside monophosphate biosynthetic process)|go:"GO:0016301"(kinase activity)|go:"GO:0034418"(urate biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046101"(hypoxanthine biosynthetic process)|interpro:IPR000836(Phosphoribosyltransferase)|interpro:IPR000842(Phosphoribosyl pyrophosphate synthetase, conserved site)|interpro:IPR005946(Phosphoribosyl pyrophosphokinase)|go:"GO:0006144"(purine nucleobase metabolic process)|interpro:IPR029057|interpro:IPR029099|interpro:IPR037515|rcsb pdb:2H06|rcsb pdb:2H07|rcsb pdb:2H08|rcsb pdb:2HCR|rcsb pdb:3EFH|rcsb pdb:3S5J|rcsb pdb:4F8E|rcsb pdb:4LYG|rcsb pdb:4LZN|rcsb pdb:4LZO|rcsb pdb:4M0P|rcsb pdb:4M0U|reactome:R-HSA-73843|dip:DIP-61999N	-	crc64:66699F37B0013088	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:+Hih2M7JLTsjEglauBlPj182h9M9606	intact-crc:1DC41DBFB83FA1E2|rigid:EEjOnv8wbKDeIzNK2fZ28hS+xLw	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P60709	uniprotkb:P38340	intact:EBI-353944|uniprotkb:P02570|uniprotkb:P70514|uniprotkb:P99021|uniprotkb:Q11211|uniprotkb:Q64316|uniprotkb:Q75MN2|uniprotkb:Q96B34|uniprotkb:Q96HG5|ensembl:ENSP00000494269|ensembl:ENSP00000494750|ensembl:ENSP00000495995|ensembl:ENSP00000501862|ensembl:ENSP00000502821	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:actb_human(display_long)|uniprotkb:ACTB(gene name)|psi-mi:ACTB(display_short)|uniprotkb:Beta-actin(gene name synonym)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550416|imex:IM-24995-3175	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001092.1|ensembl:ENSG00000075624(gene)|ensembl:ENST00000493945(transcript)|ensembl:ENST00000642480(transcript)|ensembl:ENST00000646664(transcript)|ensembl:ENST00000674681(transcript)|ensembl:ENST00000675515(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000785"(chromatin)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0001895"(retina homeostasis)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007409"(axonogenesis)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019894"(kinesin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0022898"(regulation of transmembrane transporter activity)|go:"GO:0030027"(lamellipodium)|go:"GO:0030424"(axon)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0030957"(Tat protein binding)|go:"GO:0031982"(vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034333"(adherens junction assembly)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043044"|go:"GO:0043296"(apical junction complex)|go:"GO:0044305"(calyx of Held)|go:"GO:0045176"(apical protein localization)|go:"GO:0045202"(synapse)|go:"GO:0048156"(tau protein binding)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048870"(cell motility)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051621"(regulation of norepinephrine uptake)|go:"GO:0051623"(positive regulation of norepinephrine uptake)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070160"(tight junction)|go:"GO:0070527"(platelet aggregation)|reactome:R-HSA-4420097|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0072562"(blood microparticle)|go:"GO:0072749"(cellular response to cytochalasin B)|go:"GO:0097433"(dense body)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098973"(structural constituent of postsynaptic actin cytoskeleton)|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0150111"(regulation of transepithelial transport)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P60709|rcsb pdb:3BYH|rcsb pdb:3D2U|rcsb pdb:3J82|rcsb pdb:3LUE|rcsb pdb:6ANU|rcsb pdb:6ICT|rcsb pdb:6ICV|rcsb pdb:6LTJ|rcsb pdb:6MBJ|rcsb pdb:6MBK|rcsb pdb:6MBL|rcsb pdb:6NBW|rcsb pdb:6OX0|rcsb pdb:6OX1|rcsb pdb:6OX2|rcsb pdb:6OX3|rcsb pdb:6OX4|rcsb pdb:6OX5|rcsb pdb:6V62|rcsb pdb:6V63|rcsb pdb:6WK1|rcsb pdb:6WK2|rcsb pdb:7AS4|reactome:R-HSA-1445148|reactome:R-HSA-190873|reactome:R-HSA-196025|reactome:R-HSA-2029482|reactome:R-HSA-3214847|reactome:R-HSA-389957|reactome:R-HSA-390450|reactome:R-HSA-3928662|reactome:R-HSA-3928665|reactome:R-HSA-418990|reactome:R-HSA-437239|reactome:R-HSA-446353|reactome:R-HSA-5250924|reactome:R-HSA-5626467|reactome:R-HSA-5663213|reactome:R-HSA-5663220|reactome:R-HSA-5674135|reactome:R-HSA-5689603|reactome:R-HSA-5696394|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8856828|reactome:R-HSA-9035034|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9662360|reactome:R-HSA-9662361|reactome:R-HSA-9664422|reactome:R-HSA-983231|reactome:R-HSA-445095|dip:DIP-29686N	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F	-	-	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:Hoge1B8Pn56kvbNTpkSLsQuHwRc9606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:8F45761BAAD0C0F5|rigid:dOsk2RtACj0gTuWtoa2+2MORKdE	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P60010	uniprotkb:P60709	intact:EBI-2169|uniprotkb:P02579|uniprotkb:Q9P3X6|uniprotkb:Q9P3X7|uniprotkb:D6VTJ1|ensemblfungi:YFL039C	intact:EBI-353944|uniprotkb:P02570|uniprotkb:P70514|uniprotkb:P99021|uniprotkb:Q11211|uniprotkb:Q64316|uniprotkb:Q75MN2|uniprotkb:Q96B34|uniprotkb:Q96HG5|ensembl:ENSP00000494269|ensembl:ENSP00000494750|ensembl:ENSP00000495995|ensembl:ENSP00000501862|ensembl:ENSP00000502821	psi-mi:act_yeast(display_long)|uniprotkb:ACT1(gene name)|psi-mi:ACT1(display_short)|uniprotkb:ABY1(gene name synonym)|uniprotkb:END7(gene name synonym)|uniprotkb:YFL039C(locus name)	psi-mi:actb_human(display_long)|uniprotkb:ACTB(gene name)|psi-mi:ACTB(display_short)|uniprotkb:Beta-actin(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550412|imex:IM-24995-3174	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_116614.1|sgd:S000001855|dip:DIP-310N|mint:P60010|ensemblfungi:YFL039C(gene)|ensemblfungi:YFL039C_mRNA(transcript)|go:"GO:0000011"(vacuole inheritance)|go:"GO:0000142"(cellular bud neck contractile ring)|go:"GO:0000812"(Swr1 complex)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005524"(ATP binding)|go:"GO:0005884"(actin filament)|go:"GO:0006281"(DNA repair)|go:"GO:0006897"(endocytosis)|go:"GO:0009306"(protein secretion)|go:"GO:0016573"(histone acetylation)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030476"(ascospore wall assembly)|go:"GO:0030479"(actin cortical patch)|go:"GO:0031011"(Ino80 complex)|go:"GO:0032432"(actin filament bundle)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:1902404"(mitotic actomyosin contractile ring contraction)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|rcsb pdb:1YAG|rcsb pdb:1YVN|rcsb pdb:5NBL|rcsb pdb:5NBM|rcsb pdb:5NBN|rcsb pdb:5Y81|reactome:R-SCE-114608|reactome:R-SCE-190873|reactome:R-SCE-196025|reactome:R-SCE-2029482|reactome:R-SCE-5626467|reactome:R-SCE-5663213|reactome:R-SCE-8856828|reactome:R-SCE-8980692|reactome:R-SCE-9013026	refseq:NP_001092.1|ensembl:ENSG00000075624(gene)|ensembl:ENST00000493945(transcript)|ensembl:ENST00000642480(transcript)|ensembl:ENST00000646664(transcript)|ensembl:ENST00000674681(transcript)|ensembl:ENST00000675515(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000785"(chromatin)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0001895"(retina homeostasis)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007409"(axonogenesis)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019894"(kinesin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0022898"(regulation of transmembrane transporter activity)|go:"GO:0030027"(lamellipodium)|go:"GO:0030424"(axon)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0030957"(Tat protein binding)|go:"GO:0031982"(vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034333"(adherens junction assembly)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043044"|go:"GO:0043296"(apical junction complex)|go:"GO:0044305"(calyx of Held)|go:"GO:0045176"(apical protein localization)|go:"GO:0045202"(synapse)|go:"GO:0048156"(tau protein binding)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048870"(cell motility)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051621"(regulation of norepinephrine uptake)|go:"GO:0051623"(positive regulation of norepinephrine uptake)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070160"(tight junction)|go:"GO:0070527"(platelet aggregation)|reactome:R-HSA-4420097|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0072562"(blood microparticle)|go:"GO:0072749"(cellular response to cytochalasin B)|go:"GO:0097433"(dense body)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098973"(structural constituent of postsynaptic actin cytoskeleton)|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0150111"(regulation of transepithelial transport)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P60709|rcsb pdb:3BYH|rcsb pdb:3D2U|rcsb pdb:3J82|rcsb pdb:3LUE|rcsb pdb:6ANU|rcsb pdb:6ICT|rcsb pdb:6ICV|rcsb pdb:6LTJ|rcsb pdb:6MBJ|rcsb pdb:6MBK|rcsb pdb:6MBL|rcsb pdb:6NBW|rcsb pdb:6OX0|rcsb pdb:6OX1|rcsb pdb:6OX2|rcsb pdb:6OX3|rcsb pdb:6OX4|rcsb pdb:6OX5|rcsb pdb:6V62|rcsb pdb:6V63|rcsb pdb:6WK1|rcsb pdb:6WK2|rcsb pdb:7AS4|reactome:R-HSA-1445148|reactome:R-HSA-190873|reactome:R-HSA-196025|reactome:R-HSA-2029482|reactome:R-HSA-3214847|reactome:R-HSA-389957|reactome:R-HSA-390450|reactome:R-HSA-3928662|reactome:R-HSA-3928665|reactome:R-HSA-418990|reactome:R-HSA-437239|reactome:R-HSA-446353|reactome:R-HSA-5250924|reactome:R-HSA-5626467|reactome:R-HSA-5663213|reactome:R-HSA-5663220|reactome:R-HSA-5674135|reactome:R-HSA-5689603|reactome:R-HSA-5696394|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8856828|reactome:R-HSA-9035034|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9662360|reactome:R-HSA-9662361|reactome:R-HSA-9664422|reactome:R-HSA-983231|reactome:R-HSA-445095|dip:DIP-29686N	-	crc64:87AC19B0B0BC9E71	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:yfgwiWq/Y0HviACqgjjUugpEKLw559292	rogid:Hoge1B8Pn56kvbNTpkSLsQuHwRc9606	intact-crc:9963DFFE7BCF6263|rigid:YgERg3OzIJM/7XW/p2uhHxVz360	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P60891	uniprotkb:P32895	intact:EBI-749195|uniprotkb:P09329|uniprotkb:B2R6T7|uniprotkb:B1ALA8|uniprotkb:B4DNL6|uniprotkb:D3DUX6|ensembl:ENSP00000361512	intact:EBI-9869|uniprotkb:D6VX20|ensemblfungi:YKL181W	psi-mi:prps1_human(display_long)|uniprotkb:Phosphoribosyl pyrophosphate synthase I(gene name synonym)|uniprotkb:PRPS1(gene name)|psi-mi:PRPS1(display_short)|uniprotkb:PPRibP(gene name synonym)	psi-mi:kpr1_yeast(display_long)|uniprotkb:PPS1(gene name synonym)|uniprotkb:PRP1(gene name synonym)|uniprotkb:PRPS(gene name synonym)|uniprotkb:PRPS1(gene name synonym)|uniprotkb:YKL181W(locus name)|uniprotkb:PRS1(gene name)|psi-mi:PRS1(display_short)|uniprotkb:Phosphoribosyl pyrophosphate synthase 1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550424|imex:IM-24995-3177	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001191331.1|refseq:NP_002755.1|ensembl:ENSG00000147224(gene)|ensembl:ENST00000372435(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0002189"(ribose phosphate diphosphokinase complex)|go:"GO:0004749"(ribose phosphate diphosphokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006015"(5-phosphoribose 1-diphosphate biosynthetic process)|go:"GO:0006164"(purine nucleotide biosynthetic process)|go:"GO:0006221"(pyrimidine nucleotide biosynthetic process)|go:"GO:0007399"(nervous system development)|go:"GO:0009116"(nucleoside metabolic process)|go:"GO:0009156"(ribonucleoside monophosphate biosynthetic process)|go:"GO:0016301"(kinase activity)|go:"GO:0034418"(urate biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046101"(hypoxanthine biosynthetic process)|interpro:IPR000836(Phosphoribosyltransferase)|interpro:IPR000842(Phosphoribosyl pyrophosphate synthetase, conserved site)|interpro:IPR005946(Phosphoribosyl pyrophosphokinase)|go:"GO:0006144"(purine nucleobase metabolic process)|interpro:IPR029057|interpro:IPR029099|interpro:IPR037515|rcsb pdb:2H06|rcsb pdb:2H07|rcsb pdb:2H08|rcsb pdb:2HCR|rcsb pdb:3EFH|rcsb pdb:3S5J|rcsb pdb:4F8E|rcsb pdb:4LYG|rcsb pdb:4LZN|rcsb pdb:4LZO|rcsb pdb:4M0P|rcsb pdb:4M0U|reactome:R-HSA-73843|dip:DIP-61999N	refseq:NP_012740.1|sgd:S000001664|ensemblfungi:YKL181W(gene)|ensemblfungi:YKL181W_mRNA(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0002189"(ribose phosphate diphosphokinase complex)|go:"GO:0004749"(ribose phosphate diphosphokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006015"(5-phosphoribose 1-diphosphate biosynthetic process)|go:"GO:0006164"(purine nucleotide biosynthetic process)|go:"GO:0009116"(nucleoside metabolic process)|go:"GO:0009156"(ribonucleoside monophosphate biosynthetic process)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016301"(kinase activity)|go:"GO:0031505"(fungal-type cell wall organization)|interpro:IPR000836(Phosphoribosyltransferase)|interpro:IPR000842(Phosphoribosyl pyrophosphate synthetase, conserved site)|interpro:IPR005946(Phosphoribosyl pyrophosphokinase)|interpro:IPR029057|interpro:IPR029099|reactome:R-SCE-73843|dip:DIP-4857N|mint:P32895	-	-	crc64:F3E93ACB25E703FF	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:+Hih2M7JLTsjEglauBlPj182h9M9606	rogid:Ea45pOje4sjYrrU7ze4Af443yDk559292	intact-crc:33FA56E10048DC5B|rigid:3TY8kxFwrUo6RAg2bNdsrGenDxc	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P61371	uniprotkb:P25377	intact:EBI-3906896|uniprotkb:P47894|uniprotkb:P20663|ensembl:ENSP00000230658	intact:EBI-2347652|uniprotkb:D6VRA5|ensemblfungi:YCR105W	psi-mi:isl1_human(display_long)|uniprotkb:ISL1(gene name)|psi-mi:ISL1(display_short)	psi-mi:adh7_yeast(display_long)|uniprotkb:ADH7(gene name)|psi-mi:ADH7(display_short)|uniprotkb:NADP-dependent alcohol dehydrogenase VII(gene name synonym)|uniprotkb:YCR105W(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550444|imex:IM-24995-3182	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002193.2|ensembl:ENSP00000230658|ensembl:ENSG00000016082(gene)|ensembl:ENST00000230658(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001755"(neural crest cell migration)|go:"GO:0003139"(secondary heart field specification)|go:"GO:0003148"(outflow tract septum morphogenesis)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0003203"(endocardial cushion morphogenesis)|go:"GO:0003215"(cardiac right ventricle morphogenesis)|go:"GO:0003266"(regulation of secondary heart field cardioblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007409"(axonogenesis)|go:"GO:0007507"(heart development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010575"(positive regulation of vascular endothelial growth factor production)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0021520"(spinal cord motor neuron cell fate specification)|go:"GO:0021522"(spinal cord motor neuron differentiation)|go:"GO:0021524"(visceral motor neuron differentiation)|go:"GO:0021559"(trigeminal nerve development)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0031016"(pancreas development)|go:"GO:0031103"(axon regeneration)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0031290"(retinal ganglion cell axon guidance)|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048665"(neuron fate specification)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0048880"(sensory system development)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0048936"(peripheral nervous system neuron axonogenesis)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0060037"(pharyngeal system development)|go:"GO:0060379"(cardiac muscle cell myoblast differentiation)|go:"GO:0060384"(innervation)|go:"GO:0060413"(atrial septum morphogenesis)|go:"GO:0060913"(cardiac cell fate determination)|go:"GO:0060931"(sinoatrial node cell development)|go:"GO:0032725"(positive regulation of granulocyte macrophage colony-stimulating factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032730"(positive regulation of interleukin-1 alpha production)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0071657"(positive regulation of granulocyte colony-stimulating factor production)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1901258"(positive regulation of macrophage colony-stimulating factor production)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001356(Homeobox)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|mint:P61371|reactome:R-HSA-400511|reactome:R-HSA-9010553	refseq:NP_010030.1|sgd:S000000702|dip:DIP-7661N|mint:P25377|ensemblfungi:YCR105W(gene)|ensemblfungi:YCR105W_mRNA(transcript)|go:"GO:0006066"(alcohol metabolic process)|go:"GO:0008106"("alcohol dehydrogenase (NADP+) activity")|go:"GO:0008270"(zinc ion binding)|go:"GO:0016616"(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|interpro:IPR002328(Alcohol dehydrogenase, zinc-containing, conserved site)|interpro:IPR011032(GroES-like)|interpro:IPR013149(Alcohol dehydrogenase, zinc-binding)|interpro:IPR013154(Alcohol dehydrogenase GroES-like)|interpro:IPR020843|interpro:IPR029752|interpro:IPR036291	-	-	crc64:BFB0E6C5F93D3F07	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:1eir7wLzkoqlwl4AfQuBtjjiyd09606	rogid:PGCt+bqhn63vUVgS5IKrrOukXgg559292	intact-crc:D2F82A672DE31990|rigid:EdWNISKdl+iTNjPZeQZyVi1XzTo	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P62714	uniprotkb:P38128	intact:EBI-1044367|ensembl:ENSP00000221138|uniprotkb:P11082|uniprotkb:D3DSV4|uniprotkb:Q6FHK5	intact:EBI-17469|uniprotkb:D6VQH6|ensemblfungi:YBR182C	psi-mi:pp2ab_human(display_long)|uniprotkb:PPP2CB(gene name)|psi-mi:PPP2CB(display_short)	psi-mi:smp1_yeast(display_long)|uniprotkb:YBR1245(orf name)|uniprotkb:YBR182C(locus name)|uniprotkb:SMP1(gene name)|psi-mi:SMP1(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550460|imex:IM-24995-3186	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001009552.1|ensembl:ENSG00000104695(gene)|ensembl:ENST00000221138(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0010288"(response to lead ion)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046872"(metal ion binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|go:"GO:0006470"(protein dephosphorylation)|interpro:IPR029052|mint:P62714|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5675221|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-6804757|reactome:R-HSA-5673000|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|dip:DIP-42325N	refseq:NP_009741.3|sgd:S000000386|interpro:IPR002100(Transcription factor, MADS-box)|ensemblfungi:YBR182C(gene)|ensemblfungi:YBR182C_mRNA(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|reactome:R-SCE-525793|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR033896|interpro:IPR036879	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:ZWmB6it7rr0BS5sy38IxZ9QdR7U9606	rogid:+iBP5NzZkrXnslYfo1RDMrlTAIQ559292	intact-crc:AB9ADB3B87CC4933|rigid:XK/kpDX0uyVVJjPhxen/wCS2Yyc	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P61457	uniprotkb:P32502	intact:EBI-740475|ensembl:ENSP00000299299|uniprotkb:P70519|uniprotkb:P80095|uniprotkb:Q9D930	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:phs_human(display_long)|uniprotkb:4-alpha-hydroxy-tetrahydropterin dehydratase(gene name synonym)|uniprotkb:Phenylalanine hydroxylase-stimulating protein(gene name synonym)|uniprotkb:Pterin carbinolamine dehydratase(gene name synonym)|uniprotkb:Dimerization cofactor of hepatocyte nuclear factor 1-alpha(gene name synonym)|uniprotkb:PCBD1(gene name)|psi-mi:PCBD1(display_short)|uniprotkb:DCOH(gene name synonym)|uniprotkb:PCBD(gene name synonym)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550448|imex:IM-24995-3183	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000272.1|ensembl:ENSG00000166228(gene)|ensembl:ENST00000299299(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004505"(phenylalanine 4-monooxygenase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006558"(L-phenylalanine metabolic process)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0008124"(4-alpha-hydroxytetrahydrobiopterin dehydratase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001533(Transcriptional coactivator/pterin dehydratase)|interpro:IPR036428|mint:P61457|reactome:R-HSA-8964208|refseq:NP_001276726.1	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731	-	-	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:WsAu8slwInyWOA2p/z+JqTvyKP49606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:439FF5DE54B45289|rigid:ws63suhiisK0D+qYFpMFXmdE6YY	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P38340	uniprotkb:P62333	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-357669|uniprotkb:Q92524|uniprotkb:P49719|uniprotkb:Q6IBU3|uniprotkb:B2R975|ensembl:ENSP00000401802	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:prs10_human(display_long)|uniprotkb:PSMC6(gene name)|psi-mi:PSMC6(display_short)|uniprotkb:SUG2(gene name synonym)|uniprotkb:Proteasome 26S subunit ATPase 6(gene name synonym)|uniprotkb:Proteasome subunit p42(gene name synonym)|uniprotkb:26S proteasome AAA-ATPase subunit RPT4(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550452|imex:IM-24995-3184	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F	refseq:NP_002797.3|ensembl:ENST00000445930(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|ensembl:ENSG00000100519(gene)|go:"GO:0005829"(cytosol)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0016234"(inclusion body)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0042802"(identical protein binding)|interpro:IPR032501|interpro:IPR035263|interpro:IPR041569|mint:P62333|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHJ|rcsb pdb:5VHM|rcsb pdb:5VHN|rcsb pdb:5VHO|rcsb pdb:5VHP|rcsb pdb:5VHQ|rcsb pdb:5VHR|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090261"(positive regulation of inclusion body assembly)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-75815|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-174184|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|dip:DIP-38150N	-	crc64:66699F37B0013088	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:QE8jzSEp1bpzhOi/oAAnV18QK249606	intact-crc:67534C20AFA88362|rigid:pDcOS7AIb75qNpuh4qYhVztcmHI	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P33297	uniprotkb:P62333	intact:EBI-13920|uniprotkb:D6W2H6|ensemblfungi:YOR117W	intact:EBI-357669|uniprotkb:Q92524|uniprotkb:P49719|uniprotkb:Q6IBU3|uniprotkb:B2R975|ensembl:ENSP00000401802	psi-mi:prs6a_yeast(display_long)|uniprotkb:RPT5(gene name)|psi-mi:RPT5(display_short)|uniprotkb:YTA1(gene name synonym)|uniprotkb:YOR117W(locus name)|uniprotkb:O3258(orf name)|uniprotkb:YOR3258W(orf name)|uniprotkb:Tat-binding protein homolog 1(gene name synonym)	psi-mi:prs10_human(display_long)|uniprotkb:PSMC6(gene name)|psi-mi:PSMC6(display_short)|uniprotkb:SUG2(gene name synonym)|uniprotkb:Proteasome 26S subunit ATPase 6(gene name synonym)|uniprotkb:Proteasome subunit p42(gene name synonym)|uniprotkb:26S proteasome AAA-ATPase subunit RPT4(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550456|imex:IM-24995-3185	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005643|rcsb pdb:3WHL|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MP9|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|rcsb pdb:3WHK|reactome:R-SCE-5689880|reactome:R-SCE-6798695|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|ensemblfungi:YOR117W(gene)|ensemblfungi:YOR117W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0070682"(proteasome regulatory particle assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035254|interpro:IPR041569|rcsb pdb:3JCO|rcsb pdb:3JCP|refseq:NP_014760.3|mint:P33297|dip:DIP-1590N	refseq:NP_002797.3|ensembl:ENST00000445930(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|ensembl:ENSG00000100519(gene)|go:"GO:0005829"(cytosol)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0016234"(inclusion body)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0042802"(identical protein binding)|interpro:IPR032501|interpro:IPR035263|interpro:IPR041569|mint:P62333|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHJ|rcsb pdb:5VHM|rcsb pdb:5VHN|rcsb pdb:5VHO|rcsb pdb:5VHP|rcsb pdb:5VHQ|rcsb pdb:5VHR|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090261"(positive regulation of inclusion body assembly)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-75815|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-174184|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|dip:DIP-38150N	-	crc64:C215422033FCE830	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:jsQE3SjBA0ZZcysuLgFe/5M6pOc559292	rogid:QE8jzSEp1bpzhOi/oAAnV18QK249606	intact-crc:8A55579BF851D584|rigid:tsQRSTFYX7nwVpP+XsHPhk23dng	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P32458	uniprotkb:P63279	intact:EBI-4178|uniprotkb:D6VWP6|ensemblfungi:YJR076C	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	psi-mi:cdc11_yeast(display_long)|uniprotkb:CDC11(gene name)|psi-mi:CDC11(display_short)|uniprotkb:PSL9(gene name synonym)|uniprotkb:YJR076C(locus name)|uniprotkb:J1833(orf name)	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550492|imex:IM-24995-3194	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012610.1|sgd:S000003837|dip:DIP-1656N|mint:P32458|ensemblfungi:YJR076C(gene)|ensemblfungi:YJR076C_mRNA(transcript)|go:"GO:0000144"(cellular bud neck septin ring)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000915"(actomyosin contractile ring assembly)|go:"GO:0000917"(division septum assembly)|go:"GO:0001400"(mating projection base)|go:"GO:0003924"(GTPase activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005619"(ascospore wall)|go:"GO:0005628"(prospore membrane)|go:"GO:0005876"(spindle microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0005935"(cellular bud neck)|go:"GO:0005940"(septin ring)|go:"GO:0010314"(phosphatidylinositol-5-phosphate binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030011"(maintenance of cell polarity)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0032160"(septin filament array)|go:"GO:0032186"(cellular bud neck septin ring organization)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042802"(identical protein binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0072687"(meiotic spindle)|go:"GO:0097271"(protein localization to bud neck)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|rcsb pdb:5AR1	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N	-	crc64:5CFFD4CD1F6C57D4	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:KRcNMx6EOTmvHb+6u15UrVoyb3s559292	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	intact-crc:F9E47B72FB731505|rigid:1L1ArCGXPA6CF4VZPo9nfrMSdDM	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P04046	uniprotkb:P63279	intact:EBI-14238|ensemblfungi:YMR300C|uniprotkb:D6W0C7	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	psi-mi:pur1_yeast(display_long)|uniprotkb:Glutamine phosphoribosylpyrophosphate amidotransferase(gene name synonym)|uniprotkb:ADE4(gene name)|psi-mi:ADE4(display_short)|uniprotkb:YMR300C(locus name)|uniprotkb:YM9952.02C(orf name)	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550488|imex:IM-24995-3193	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014029.1|sgd:S000004915|ensemblfungi:YMR300C(gene)|go:"GO:0009116"(nucleoside metabolic process)|go:"GO:0046872"(metal ion binding)|interpro:IPR000836(Phosphoribosyltransferase)|interpro:IPR005854(Amidophosphoribosyl transferase)|ensemblfungi:YMR300C_mRNA(transcript)|go:"GO:0004044"(amidophosphoribosyltransferase activity)|go:"GO:0005737"(cytoplasm)|interpro:IPR017932|interpro:IPR029055|interpro:IPR029057|interpro:IPR035584|go:"GO:0006164"(purine nucleotide biosynthetic process)|go:"GO:0006189"('de novo' IMP biosynthetic process)|go:"GO:0006541"(glutamine metabolic process)|go:"GO:0009113"(purine nucleobase biosynthetic process)|mint:P04046|dip:DIP-6727N	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N	-	crc64:1FE7A6F5B7C96710	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:v3Q2NjIC4OuMxGAFnC+1r4y70mw559292	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	intact-crc:6E59370198434C67|rigid:emC0gnGMB34N9GN/LUQPL3YvnPk	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P63279	uniprotkb:P40956	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	intact:EBI-7968|uniprotkb:D6VTX2|ensemblfungi:YGL181W	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:gts1_yeast(display_long)|uniprotkb:YGL181W(locus name)|uniprotkb:GTS1(gene name)|psi-mi:GTS1(display_short)|uniprotkb:LSR1(gene name synonym)|uniprotkb:Protein LSR1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550484|imex:IM-24995-3192	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N	refseq:NP_011334.1|sgd:S000003149|mint:P40956|dip:DIP-2746N|ensemblfungi:YGL181W(gene)|ensemblfungi:YGL181W_mRNA(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0006897"(endocytosis)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010512"(negative regulation of phosphatidylinositol biosynthetic process)|go:"GO:0030479"(actin cortical patch)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR037278|interpro:IPR038508	-	-	crc64:D687E3BF6B620795	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	rogid:8kgpssCRrHiTHsFaOH2nDK6EIjk559292	intact-crc:6D06E44B447F21A3|rigid:wtK95pRnYCE8bf/gF5tg06A8uk8	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P38769	uniprotkb:P63010-2	intact:EBI-24503|uniprotkb:D3DKY2|ensemblfungi:YHR035W	intact:EBI-11529439|ensembl:ENSP00000482835|ensembl:ENSP00000483185	psi-mi:nel1_yeast(display_long)|uniprotkb:NEL1(gene name)|psi-mi:NEL1(display_short)|uniprotkb:Non-ERES-localized SEC23 homolog 1(gene name synonym)|uniprotkb:YHR035W(locus name)	psi-mi:p63010-2(display_long)|uniprotkb:ADTB2(gene name synonym)|uniprotkb:AP105B(gene name synonym)|uniprotkb:Adaptor protein complex AP-2 subunit beta(gene name synonym)|uniprotkb:Adaptor-related protein complex 2 subunit beta(gene name synonym)|uniprotkb:Beta-2-adaptin(gene name synonym)|uniprotkb:Beta-adaptin(gene name synonym)|uniprotkb:CLAPB1(gene name synonym)|uniprotkb:Clathrin assembly protein complex 2 beta large chain(gene name synonym)|uniprotkb:AP2B1(gene name)|psi-mi:AP2B1(display_short)|uniprotkb:Plasma membrane adaptor HA2/AP2 adaptin beta subunit(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550464|imex:IM-24995-3187	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011900.1|sgd:S000001077|dip:DIP-806N|mint:P38769|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:0090110"(COPII-coated vesicle cargo loading)|interpro:IPR006896(Sec23/Sec24 trunk region)|interpro:IPR036174|interpro:IPR036180|interpro:IPR036465|interpro:IPR037364|ensemblfungi:YHR035W_mRNA(transcript)|ensemblfungi:YHR035W(gene)	intact:EBI-432924(isoform-parent)|uniprotkb:P63010-2(isoform-parent)|ensembl:ENSG00000006125(gene)|ensembl:ENST00000610402(transcript)|ensembl:ENST00000618940(transcript)	-	crc64:C42D24351D4FA75D	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:qiEwgSjz+4y1ObyBwCewGx9/NPc559292	rogid:RpFHKbLgdxGqagTUoCCgQ2W+9nw9606	intact-crc:A84E9FB35921B891|rigid:VzAs8w+jsKqLm4oY1Hmkgr7Iy8o	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P63261	uniprotkb:P38340	intact:EBI-351292|uniprotkb:P02571|uniprotkb:P14104|uniprotkb:P99022|uniprotkb:Q5U032|uniprotkb:Q96E67|uniprotkb:A8K7C2|ensembl:ENSP00000505060|ensembl:ENSP00000505193|ensembl:ENSP00000505235|ensembl:ENSP00000506126|ensembl:ENSP00000506201|ensembl:ENSP00000506253|ensembl:ENSP00000458162|ensembl:ENSP00000458435|ensembl:ENSP00000459119|ensembl:ENSP00000459124|ensembl:ENSP00000460464|ensembl:ENSP00000460660|ensembl:ENSP00000461672|ensembl:ENSP00000466346|ensembl:ENSP00000477968	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:actg_human(display_long)|uniprotkb:ACTG1(gene name)|psi-mi:ACTG1(display_short)|uniprotkb:ACTG(gene name synonym)|uniprotkb:Gamma-actin(gene name synonym)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550476|imex:IM-24995-3190	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001186883.1|refseq:NP_001605.1|ensembl:ENST00000570382(transcript)|ensembl:ENSG00000184009(gene)|ensembl:ENST00000571721(transcript)|ensembl:ENST00000573283(transcript)|ensembl:ENST00000575087(transcript)|ensembl:ENST00000575659(transcript)|ensembl:ENST00000575842(transcript)|ensembl:ENST00000575994(transcript)|ensembl:ENST00000576544(transcript)|ensembl:ENST00000615544(transcript)|ensembl:ENST00000679480(transcript)|ensembl:ENST00000679778(transcript)|ensembl:ENST00000680227(transcript)|ensembl:ENST00000680727(transcript)|ensembl:ENST00000681052(transcript)|ensembl:ENST00000681842(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0001895"(retina homeostasis)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005522"(profilin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0030016"(myofibril)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031941"(filamentous actin)|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0044305"(calyx of Held)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0051492"(regulation of stress fiber assembly)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070527"(platelet aggregation)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0072562"(blood microparticle)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0097433"(dense body)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098973"(structural constituent of postsynaptic actin cytoskeleton)|go:"GO:0120192"(tight junction assembly)|go:"GO:0120220"(basal body patch)|go:"GO:0150111"(regulation of transepithelial transport)|go:"GO:1902396"(protein localization to bicellular tight junction)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P63261|rcsb pdb:5JLH|rcsb pdb:6CXI|rcsb pdb:6CXJ|rcsb pdb:6G2T|rcsb pdb:6V62|rcsb pdb:6V63|rcsb pdb:6WK1|rcsb pdb:6WK2|reactome:R-HSA-1445148|reactome:R-HSA-190873|reactome:R-HSA-196025|reactome:R-HSA-2029482|reactome:R-HSA-3928662|reactome:R-HSA-3928665|reactome:R-HSA-418990|reactome:R-HSA-437239|reactome:R-HSA-4420097|reactome:R-HSA-445095|reactome:R-HSA-446353|reactome:R-HSA-5626467|reactome:R-HSA-5663213|reactome:R-HSA-5663220|reactome:R-HSA-5674135|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8856828|reactome:R-HSA-9013418|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9662360|reactome:R-HSA-9662361|reactome:R-HSA-9664422	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F	-	-	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:B2OOsE06lTfo90H3g8tlmUJQ7cY9606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:FB08903E481CF476|rigid:MnDFBVJYjyHANBw0C0Mv5JYfEM0	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P63261	uniprotkb:P60010	intact:EBI-351292|uniprotkb:P02571|uniprotkb:P14104|uniprotkb:P99022|uniprotkb:Q5U032|uniprotkb:Q96E67|uniprotkb:A8K7C2|ensembl:ENSP00000505060|ensembl:ENSP00000505193|ensembl:ENSP00000505235|ensembl:ENSP00000506126|ensembl:ENSP00000506201|ensembl:ENSP00000506253|ensembl:ENSP00000458162|ensembl:ENSP00000458435|ensembl:ENSP00000459119|ensembl:ENSP00000459124|ensembl:ENSP00000460464|ensembl:ENSP00000460660|ensembl:ENSP00000461672|ensembl:ENSP00000466346|ensembl:ENSP00000477968	intact:EBI-2169|uniprotkb:P02579|uniprotkb:Q9P3X6|uniprotkb:Q9P3X7|uniprotkb:D6VTJ1|ensemblfungi:YFL039C	psi-mi:actg_human(display_long)|uniprotkb:ACTG1(gene name)|psi-mi:ACTG1(display_short)|uniprotkb:ACTG(gene name synonym)|uniprotkb:Gamma-actin(gene name synonym)	psi-mi:act_yeast(display_long)|uniprotkb:ACT1(gene name)|psi-mi:ACT1(display_short)|uniprotkb:ABY1(gene name synonym)|uniprotkb:END7(gene name synonym)|uniprotkb:YFL039C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550472|imex:IM-24995-3189	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001186883.1|refseq:NP_001605.1|ensembl:ENST00000570382(transcript)|ensembl:ENSG00000184009(gene)|ensembl:ENST00000571721(transcript)|ensembl:ENST00000573283(transcript)|ensembl:ENST00000575087(transcript)|ensembl:ENST00000575659(transcript)|ensembl:ENST00000575842(transcript)|ensembl:ENST00000575994(transcript)|ensembl:ENST00000576544(transcript)|ensembl:ENST00000615544(transcript)|ensembl:ENST00000679480(transcript)|ensembl:ENST00000679778(transcript)|ensembl:ENST00000680227(transcript)|ensembl:ENST00000680727(transcript)|ensembl:ENST00000681052(transcript)|ensembl:ENST00000681842(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0001895"(retina homeostasis)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005522"(profilin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0030016"(myofibril)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031941"(filamentous actin)|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0044305"(calyx of Held)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0051492"(regulation of stress fiber assembly)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070527"(platelet aggregation)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0072562"(blood microparticle)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0097433"(dense body)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098973"(structural constituent of postsynaptic actin cytoskeleton)|go:"GO:0120192"(tight junction assembly)|go:"GO:0120220"(basal body patch)|go:"GO:0150111"(regulation of transepithelial transport)|go:"GO:1902396"(protein localization to bicellular tight junction)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P63261|rcsb pdb:5JLH|rcsb pdb:6CXI|rcsb pdb:6CXJ|rcsb pdb:6G2T|rcsb pdb:6V62|rcsb pdb:6V63|rcsb pdb:6WK1|rcsb pdb:6WK2|reactome:R-HSA-1445148|reactome:R-HSA-190873|reactome:R-HSA-196025|reactome:R-HSA-2029482|reactome:R-HSA-3928662|reactome:R-HSA-3928665|reactome:R-HSA-418990|reactome:R-HSA-437239|reactome:R-HSA-4420097|reactome:R-HSA-445095|reactome:R-HSA-446353|reactome:R-HSA-5626467|reactome:R-HSA-5663213|reactome:R-HSA-5663220|reactome:R-HSA-5674135|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8856828|reactome:R-HSA-9013418|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9662360|reactome:R-HSA-9662361|reactome:R-HSA-9664422	refseq:NP_116614.1|sgd:S000001855|dip:DIP-310N|mint:P60010|ensemblfungi:YFL039C(gene)|ensemblfungi:YFL039C_mRNA(transcript)|go:"GO:0000011"(vacuole inheritance)|go:"GO:0000142"(cellular bud neck contractile ring)|go:"GO:0000812"(Swr1 complex)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005524"(ATP binding)|go:"GO:0005884"(actin filament)|go:"GO:0006281"(DNA repair)|go:"GO:0006897"(endocytosis)|go:"GO:0009306"(protein secretion)|go:"GO:0016573"(histone acetylation)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030476"(ascospore wall assembly)|go:"GO:0030479"(actin cortical patch)|go:"GO:0031011"(Ino80 complex)|go:"GO:0032432"(actin filament bundle)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:1902404"(mitotic actomyosin contractile ring contraction)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|rcsb pdb:1YAG|rcsb pdb:1YVN|rcsb pdb:5NBL|rcsb pdb:5NBM|rcsb pdb:5NBN|rcsb pdb:5Y81|reactome:R-SCE-114608|reactome:R-SCE-190873|reactome:R-SCE-196025|reactome:R-SCE-2029482|reactome:R-SCE-5626467|reactome:R-SCE-5663213|reactome:R-SCE-8856828|reactome:R-SCE-8980692|reactome:R-SCE-9013026	-	-	crc64:87AC19B0B0BC9E71	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:B2OOsE06lTfo90H3g8tlmUJQ7cY9606	rogid:yfgwiWq/Y0HviACqgjjUugpEKLw559292	intact-crc:B0FF3386D00D98AA|rigid:RZtrroqUOrg1ChAbVxQhz5fMr1w	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P46680	uniprotkb:P63261	intact:EBI-2406|uniprotkb:D6VZR5|ensemblfungi:YMR092C	intact:EBI-351292|uniprotkb:P02571|uniprotkb:P14104|uniprotkb:P99022|uniprotkb:Q5U032|uniprotkb:Q96E67|uniprotkb:A8K7C2|ensembl:ENSP00000505060|ensembl:ENSP00000505193|ensembl:ENSP00000505235|ensembl:ENSP00000506126|ensembl:ENSP00000506201|ensembl:ENSP00000506253|ensembl:ENSP00000458162|ensembl:ENSP00000458435|ensembl:ENSP00000459119|ensembl:ENSP00000459124|ensembl:ENSP00000460464|ensembl:ENSP00000460660|ensembl:ENSP00000461672|ensembl:ENSP00000466346|ensembl:ENSP00000477968	psi-mi:aip1_yeast(display_long)|uniprotkb:AIP1(gene name)|psi-mi:AIP1(display_short)|uniprotkb:YM9582.17C(orf name)|uniprotkb:YMR092C(locus name)	psi-mi:actg_human(display_long)|uniprotkb:ACTG1(gene name)|psi-mi:ACTG1(display_short)|uniprotkb:ACTG(gene name synonym)|uniprotkb:Gamma-actin(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550468|imex:IM-24995-3188	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013810.1|sgd:S000004698|reactome:R-SCE-114608|dip:DIP-890N|ensemblfungi:YMR092C(gene)|ensemblfungi:YMR092C_mRNA(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005884"(actin filament)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030479"(actin cortical patch)|go:"GO:0030836"(positive regulation of actin filament depolymerization)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032466"(negative regulation of cytokinesis)|go:"GO:0043332"(mating projection tip)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|rcsb pdb:1PGU|rcsb pdb:1PI6	refseq:NP_001186883.1|refseq:NP_001605.1|ensembl:ENST00000570382(transcript)|ensembl:ENSG00000184009(gene)|ensembl:ENST00000571721(transcript)|ensembl:ENST00000573283(transcript)|ensembl:ENST00000575087(transcript)|ensembl:ENST00000575659(transcript)|ensembl:ENST00000575842(transcript)|ensembl:ENST00000575994(transcript)|ensembl:ENST00000576544(transcript)|ensembl:ENST00000615544(transcript)|ensembl:ENST00000679480(transcript)|ensembl:ENST00000679778(transcript)|ensembl:ENST00000680227(transcript)|ensembl:ENST00000680727(transcript)|ensembl:ENST00000681052(transcript)|ensembl:ENST00000681842(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0001895"(retina homeostasis)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005522"(profilin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0030016"(myofibril)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031941"(filamentous actin)|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0044305"(calyx of Held)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0051492"(regulation of stress fiber assembly)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070527"(platelet aggregation)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0072562"(blood microparticle)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0097433"(dense body)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098973"(structural constituent of postsynaptic actin cytoskeleton)|go:"GO:0120192"(tight junction assembly)|go:"GO:0120220"(basal body patch)|go:"GO:0150111"(regulation of transepithelial transport)|go:"GO:1902396"(protein localization to bicellular tight junction)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P63261|rcsb pdb:5JLH|rcsb pdb:6CXI|rcsb pdb:6CXJ|rcsb pdb:6G2T|rcsb pdb:6V62|rcsb pdb:6V63|rcsb pdb:6WK1|rcsb pdb:6WK2|reactome:R-HSA-1445148|reactome:R-HSA-190873|reactome:R-HSA-196025|reactome:R-HSA-2029482|reactome:R-HSA-3928662|reactome:R-HSA-3928665|reactome:R-HSA-418990|reactome:R-HSA-437239|reactome:R-HSA-4420097|reactome:R-HSA-445095|reactome:R-HSA-446353|reactome:R-HSA-5626467|reactome:R-HSA-5663213|reactome:R-HSA-5663220|reactome:R-HSA-5674135|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8856828|reactome:R-HSA-9013418|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9662360|reactome:R-HSA-9662361|reactome:R-HSA-9664422	-	crc64:B8340BF68DD08257	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:TwLC/U+xqc7crYws+782F2f1rEo559292	rogid:B2OOsE06lTfo90H3g8tlmUJQ7cY9606	intact-crc:05262F4D263CFF9B|rigid:cPDgvvGA0FJRLriPJYA+vCDTtGQ	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P27515	uniprotkb:P63279	intact:EBI-20151|uniprotkb:D6W1I7|ensemblfungi:YNR012W	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	psi-mi:urk1_yeast(display_long)|uniprotkb:URK1(gene name)|psi-mi:URK1(display_short)|uniprotkb:YNR012W(locus name)|uniprotkb:N2050(orf name)|uniprotkb:Uridine monophosphokinase(gene name synonym)	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550480|imex:IM-24995-3191	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014409.1|sgd:S000005295|ensemblfungi:YNR012W(gene)|ensemblfungi:YNR012W_mRNA(transcript)|go:"GO:0004849"(uridine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008655"(pyrimidine-containing compound salvage)|go:"GO:0009116"(nucleoside metabolic process)|go:"GO:0044206"(UMP salvage)|go:"GO:0044211"(CTP salvage)|interpro:IPR000764(Uridine kinase)|interpro:IPR000836(Phosphoribosyltransferase)|interpro:IPR006083(Phosphoribulokinase/uridine kinase)|interpro:IPR027417|interpro:IPR029057|dip:DIP-1720N|reactome:R-SCE-196807|reactome:R-SCE-73614	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N	-	crc64:30A0592899BCD040	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:0b4r1zm128hRdLTzXIPi6wctZZE559292	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	intact-crc:75EEB3E0C303A357|rigid:yK2Y7p5AY+W2Gkq+u9zS/BqQUX4	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P38838	uniprotkb:P63279	intact:EBI-24737|uniprotkb:D3DL83|ensemblfungi:YHR134W	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	psi-mi:wss1_yeast(display_long)|uniprotkb:YHR134W(locus name)|uniprotkb:WSS1(gene name)|psi-mi:WSS1(display_short)|uniprotkb:Weak suppressor of SMT3 protein 1(gene name synonym)|uniprotkb:DNA damage response protein WSS1(gene name synonym)|uniprotkb:SUMO-dependent isopeptidase WSS1(gene name synonym)	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550524|imex:IM-24995-3202	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012002.1|sgd:S000001176|dip:DIP-1600N|ensemblfungi:YHR134W(gene)|ensemblfungi:YHR134W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0006508"(proteolysis)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0010224"(response to UV-B)|go:"GO:0010225"(response to UV-C)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019985"(translesion synthesis)|go:"GO:0032183"(SUMO binding)|go:"GO:0036205"(histone catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0061665"(SUMO ligase activity)|go:"GO:0106300"(protein-DNA covalent cross-linking repair)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|go:"GO:1990466"(protein autosumoylation)|interpro:IPR013536(WLM)	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:nRxYgrZjnBdPN8uneoPl3Rq01+g559292	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	intact-crc:663FEAB907E3C22B|rigid:mRIfEHJp/M50+xqUmA9KVh7Eb1c	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P35192	uniprotkb:P63279	intact:EBI-10346|ensemblfungi:YMR021C|uniprotkb:D6VZJ5|uniprotkb:E9P8Z5	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	psi-mi:mac1_yeast(display_long)|uniprotkb:MAC1(gene name)|psi-mi:MAC1(display_short)|uniprotkb:CUA1(gene name synonym)|uniprotkb:YMR021C(locus name)|uniprotkb:YM9711.11C(orf name)	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550520|imex:IM-24995-3201	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013734.1|sgd:S000004623|ensemblfungi:YMR021C(gene)|ensemblfungi:YMR021C_mRNA(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005507"(copper ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0006878"(cellular copper ion homeostasis)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR036395|interpro:IPR001083(Copper fist DNA-binding)|dip:DIP-4851N	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:qm/hIB5eRjjEZv9H+Zng34N5ops559292	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	intact-crc:4ED60D9B66CF2ECC|rigid:FKAl0qhsW7XehKRyWFSuNYvGXFk	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P40473	uniprotkb:P63279	intact:EBI-25207|uniprotkb:D6VVG5|ensemblfungi:YIL122W	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	psi-mi:pog1_yeast(display_long)|uniprotkb:YIL122W(locus name)|uniprotkb:POG1(gene name)|psi-mi:POG1(display_short)|uniprotkb:Promoter of growth protein 1(gene name synonym)	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550516|imex:IM-24995-3200	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000001384|refseq:NP_012144.1|dip:DIP-2755N|ensemblfungi:YIL122W(gene)|ensemblfungi:YIL122W_mRNA(transcript)|go:"GO:0000321"(re-entry into mitotic cell cycle after pheromone arrest)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051301"(cell division)	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:SL7E0QbXBSeu+JDSQhp7p5rNb8M559292	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	intact-crc:9C3AADED1D22D303|rigid:ex6IWOlG9aqouyaWAdEOM1N7cHs	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P38986	uniprotkb:P63279	intact:EBI-3014|uniprotkb:D6VSV3|ensemblfungi:YDR321W	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	psi-mi:aspg1_yeast(display_long)|uniprotkb:YDR321W(locus name)|uniprotkb:D9798.6(orf name)|uniprotkb:ASP1(gene name)|psi-mi:ASP1(display_short)|uniprotkb:L-asparaginase I(gene name synonym)|uniprotkb:L-asparagine amidohydrolase I(gene name synonym)	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550496|imex:IM-24995-3195	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002729|refseq:NP_010607.3|dip:DIP-4030N|mint:P38986|ensemblfungi:YDR321W(gene)|ensemblfungi:YDR321W_mRNA(transcript)|go:"GO:0004067"(asparaginase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006530"(asparagine catabolic process)|go:"GO:0042597"(periplasmic space)|interpro:IPR004550(L-asparaginase, type II)|interpro:IPR006034(Asparaginase/glutaminase)|interpro:IPR020827|interpro:IPR027473|interpro:IPR027474|interpro:IPR027475|interpro:IPR036152|interpro:IPR037152|interpro:IPR040919	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N	-	crc64:8204CB7C58B5B75F	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:vIy3riBmCKfYQjsh3cIcO7o1Bzw559292	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	intact-crc:7093F78483391A83|rigid:5tyG65EjXp2hDPPyg7E12KfBvvE	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P53252	uniprotkb:P63279	intact:EBI-23225|uniprotkb:D6VUL8|ensemblfungi:YGR086C	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	psi-mi:pil1_yeast(display_long)|uniprotkb:YGR086C(locus name)|uniprotkb:PIL1(gene name)|psi-mi:PIL1(display_short)	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550508|imex:IM-24995-3198	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003318|refseq:NP_011600.3|dip:DIP-4618N|mint:P53252|ensemblfungi:YGR086C(gene)|ensemblfungi:YGR086C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0005886"(plasma membrane)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006897"(endocytosis)|go:"GO:0008104"(protein localization)|go:"GO:0008289"(lipid binding)|go:"GO:0009408"(response to heat)|go:"GO:0032126"(eisosome)|go:"GO:0036286"(eisosome filament)|go:"GO:0070941"(eisosome assembly)|go:"GO:0071944"(cell periphery)|go:"GO:0097446"(protein localization to eisosome filament)|interpro:IPR027267|interpro:IPR028245	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N	-	crc64:C86AE5ABB508EA03	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:OtBCHiFwxzPwPX5y1oMTFqlc1Po559292	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	intact-crc:1E765D81B5711FD0|rigid:8zEfk4Ahxs5xtk9FgPDZWRHYZBM	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P40151	uniprotkb:P63279	intact:EBI-29152|uniprotkb:D6W0X2|ensemblfungi:YNL218W	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	psi-mi:wrip1_yeast(display_long)|uniprotkb:Maintenance of genome stability protein 1(gene name synonym)|uniprotkb:YNL218W(locus name)|uniprotkb:N1302(orf name)|uniprotkb:MGS1(gene name)|psi-mi:MGS1(display_short)	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550504|imex:IM-24995-3197	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014181.1|sgd:S000005162|dip:DIP-1638N|ensemblfungi:YNL218W(gene)|ensemblfungi:YNL218W_mRNA(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0017116"(single-stranded DNA helicase activity)|go:"GO:0033567"(DNA replication, Okazaki fragment processing)|go:"GO:0046872"(metal ion binding)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR006642(Zinc finger, Rad18-type putative)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR021886|interpro:IPR027417|interpro:IPR032423	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:p3Wxu3/I3MK3y5fH85a0FFsg2Qo559292	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	intact-crc:D9CDC3E2F933ECC0|rigid:F75dw3xBEpoULeIzUTw1/2dCaaU	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P63279	uniprotkb:P25611	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	intact:EBI-22052|uniprotkb:D6VRA6|ensemblfungi:YCR106W	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:rds1_yeast(display_long)|uniprotkb:YCR106W(locus name)|uniprotkb:RDS1(gene name)|psi-mi:RDS1(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550500|imex:IM-24995-3196	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N	refseq:NP_010031.1|sgd:S000000703|dip:DIP-2014N|ensemblfungi:YCR106W(gene)|ensemblfungi:YCR106W_mRNA(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009410"(response to xenobiotic stimulus)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR001138(Fungal transcriptional regulatory protein, N-terminal)|interpro:IPR036864|mint:P25611	-	-	crc64:7DF91D86AF08E4E3	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	rogid:1um+FEn46D2/f4P58Zo/rIQSEZU559292	intact-crc:7001061D4DC478F8|rigid:tbMuMDUh0kZb/AIj+CkKwP4JPyw	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P25515	uniprotkb:P63279	intact:EBI-7739233|ensemblfungi:YEL027W|intact:MINT-1353979|uniprotkb:D3DLM1	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	psi-mi:vatl1_yeast(display_long)|uniprotkb:VMA3(gene name)|psi-mi:VMA3(display_short)|uniprotkb:CLS7(gene name synonym)|uniprotkb:CUP5(gene name synonym)|uniprotkb:GEF2(gene name synonym)|uniprotkb:YEL027W(locus name)|uniprotkb:Vacuolar proton pump c subunit(gene name synonym)|uniprotkb:V-ATPase 16 kDa proteolipid subunit 1(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor 2(gene name synonym)	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550512|imex:IM-24995-3199	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR002379(ATPase, F0/V0 complex, subunit C)|interpro:IPR011555(ATPase, V0 complex, proteolipid subunit C, eukaryotic)|interpro:IPR035921|rcsb pdb:3J9T|rcsb pdb:3J9U|rcsb pdb:3J9V|rcsb pdb:5TJ5|rcsb pdb:5VOX|rcsb pdb:5VOY|rcsb pdb:5VOZ|rcsb pdb:6C6L|rcsb pdb:6M0R|rcsb pdb:6M0S|rcsb pdb:6O7T|rcsb pdb:6O7U|rcsb pdb:6O7V|rcsb pdb:6O7W|rcsb pdb:6O7X|rcsb pdb:6PE4|rcsb pdb:6PE5|reactome:R-SCE-1222556|reactome:R-SCE-6798695|reactome:R-SCE-77387|reactome:R-SCE-917977|reactome:R-SCE-9639288|ensemblfungi:YEL027W(gene)|ensemblfungi:YEL027W_mRNA(transcript)|go:"GO:0000220"(vacuolar proton-transporting V-type ATPase, V0 domain)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006878"(cellular copper ion homeostasis)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0006897"(endocytosis)|go:"GO:0007033"(vacuole organization)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR000245(ATPase, V0 complex, proteolipid subunit C,)|sgd:S000000753|mint:P25515|refseq:NP_010887.3|dip:DIP-8123N	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N	-	crc64:FB8A142FFA1FA964|comment:mint|function:Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. It is an electrogenic proton pump that generates a proton motive force of 180 mv, inside positive and acidic, in the vacuolar membrane vesicles	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:MAXfIOCwZyeV4Vy1T0eKqIbS4ZQ559292	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	intact-crc:272D646094882910|rigid:+lYpw9WhGGP2lQbI4FItuk7aeGw	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P53174	uniprotkb:P63279	intact:EBI-6200|uniprotkb:D6VU88|ensemblfungi:YGL053W	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	psi-mi:prm8_yeast(display_long)|uniprotkb:PRM8(gene name)|psi-mi:PRM8(display_short)|uniprotkb:DUP1(gene name synonym)|uniprotkb:DUP240 protein PRM8(gene name synonym)|uniprotkb:Protein DUP1(gene name synonym)|uniprotkb:YGL053W(locus name)	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550552|imex:IM-24995-3209	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003021|refseq:NP_011462.1|dip:DIP-4067N|ensemblfungi:YGL053W(gene)|ensemblfungi:YGL053W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016192"(vesicle-mediated transport)|interpro:IPR001142(Yeast membrane protein DUP)	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:rE9bUEB99azFFpZn5BA9/+Fhws8559292	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	intact-crc:7B173CEDA6175B0C|rigid:CV9iIx2ViQs/XU2hxbBckXZun4s	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P63279	uniprotkb:P38340	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550548|imex:IM-24995-3208	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F	-	-	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:D11605EB0CA7750D|rigid:yPWLvTo5VQGN2yAOaM1tPNCnHvg	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P63279	uniprotkb:P53286	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	intact:EBI-3796|uniprotkb:D6VUS2|ensemblfungi:YGR142W	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:btn2_yeast(display_long)|uniprotkb:YGR142W(locus name)|uniprotkb:BTN2(gene name)|psi-mi:BTN2(display_short)|uniprotkb:Batten disease protein 2(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550544|imex:IM-24995-3207	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N	sgd:S000003374|refseq:NP_011658.3|dip:DIP-5534N|mint:P53286|ensemblfungi:YGR142W(gene)|ensemblfungi:YGR142W_mRNA(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005634"(nucleus)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006865"(amino acid transport)|go:"GO:0006885"(regulation of pH)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051087"(chaperone binding)|go:"GO:0140311"(protein sequestering activity)	-	-	crc64:E7AE1EB1E3612F3E	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	rogid:Cu27xkwGMNyS4zLvUaG1UeH2mE0559292	intact-crc:DB53A83DFB545888|rigid:gK6tt7o2LgaREYUhL/GCgAqYw1o	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P63279	uniprotkb:P32502	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550528|imex:IM-24995-3203	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731	-	-	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:1C97BA9AD4AC1F60|rigid:J5OBNYvMFV2v9zhlut1DhG67OVg	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P17423	uniprotkb:P63279	intact:EBI-9685|ensemblfungi:YHR025W|uniprotkb:D3DKX2	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	psi-mi:khse_yeast(display_long)|uniprotkb:THR1(gene name)|psi-mi:THR1(display_short)|uniprotkb:YHR025W(locus name)	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550536|imex:IM-24995-3205	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YHR025W(gene)|ensemblfungi:YHR025W_mRNA(transcript)|go:"GO:0004413"(homoserine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0009088"(threonine biosynthetic process)|go:"GO:0009092"(homoserine metabolic process)|interpro:IPR000870(Homoserine kinase)|interpro:IPR006203(GHMP kinase, ATP-binding, conserved site)|interpro:IPR006204(GHMP kinase)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR020568|interpro:IPR036554|refseq:NP_011890.1|sgd:S000001067|dip:DIP-4305N|mint:P17423	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:S6tiEUJn7YZY4ydBnYraAdecCRY559292	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	intact-crc:3DDB4A2038460A1C|rigid:KOg4s/9QXLC+PzaNW9zzYbldD3A	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P38703	uniprotkb:P63279	intact:EBI-10035|uniprotkb:Q6LD26|uniprotkb:D3DKR1|ensemblfungi:YHL003C	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	psi-mi:lag1_yeast(display_long)|uniprotkb:LAG1(gene name)|psi-mi:LAG1(display_short)|uniprotkb:Longevity assurance factor 1(gene name synonym)|uniprotkb:Longevity assurance protein 1(gene name synonym)|uniprotkb:Longevity assurance gene 1 protein(gene name synonym)|uniprotkb:Very-long-chain ceramide synthase LAG1(gene name synonym)|uniprotkb:YHL003C(locus name)	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550532|imex:IM-24995-3204	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011860.1|sgd:S000000995|ensemblfungi:YHL003C(gene)|ensemblfungi:YHL003C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016410"(N-acyltransferase activity)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:0050291"(sphingosine N-acyltransferase activity)|go:"GO:0061576"(acyl-CoA ceramide synthase complex)|interpro:IPR006634(TRAM, LAG1 and CLN8 homology)|interpro:IPR013599(TRAM1-like protein)|interpro:IPR016439(Longevity assurance, LAG1/LAC1)|reactome:R-SCE-1660661|dip:DIP-4393N|mint:P38703	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:KCAjx/gXmy0oGd3aKgasDuFHJzw559292	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	intact-crc:86C8AA128785BED1|rigid:GzR5EKIvbhutmOl+4ZPKiZuCbPE	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P63279	uniprotkb:P37263	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	intact:EBI-21659|uniprotkb:D6VR87|ensemblfungi:YCR087C-A	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:yc16_yeast(display_long)|uniprotkb:YCRX16C(orf name)|uniprotkb:YCR087C-A(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550540|imex:IM-24995-3206	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N	refseq:NP_010011.1|sgd:S000007223|mint:P37263|dip:DIP-4536N|ensemblfungi:YCR087C-A(gene)|ensemblfungi:YCR087C-A_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR014898(Zinc finger, C2H2, LYAR-type)|interpro:IPR036236|interpro:IPR039999	-	-	crc64:B5B3B4CA37B82042	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	rogid:I7iIzRqPZAKdWQSe/IeGsW0qQcU559292	intact-crc:D970E8002A121BB7|rigid:Qck8S7kbrP/Hrd/Os64j6Sm+l40	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P38319	uniprotkb:P63279	intact:EBI-20997|uniprotkb:D6VQM0|ensemblfungi:YBR223C	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	psi-mi:tydp1_yeast(display_long)|uniprotkb:TDP1(gene name)|psi-mi:TDP1(display_short)|uniprotkb:YBR1520(orf name)|uniprotkb:YBR223C(locus name)	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550560|imex:IM-24995-3211	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000000427|refseq:NP_009782.3|mint:P38319|dip:DIP-4945N|rcsb pdb:3SQ3|rcsb pdb:3SQ5|rcsb pdb:3SQ7|rcsb pdb:3SQ8|ensemblfungi:YBR223C(gene)|ensemblfungi:YBR223C_mRNA(transcript)|go:"GO:0000012"(single strand break repair)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0004527"(exonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006281"(DNA repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0017005"(3'-tyrosyl-DNA phosphodiesterase activity)|go:"GO:0070260"(5'-tyrosyl-DNA phosphodiesterase activity)|interpro:IPR010347(Tyrosyl-DNA phosphodiesterase)|rcsb pdb:1Q32	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N	-	crc64:E84C6685312DEC3F	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:VQHWWxxN+ijh3tjTmmwaPiIfGnU559292	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	intact-crc:EC4AC592461327E8|rigid:z8t5VknMUNe0ysJOGV5SKuS8VNY	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P63279	uniprotkb:P15873	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	intact:EBI-12993|uniprotkb:D6VQ89|ensemblfungi:YBR088C	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:pcna_yeast(display_long)|uniprotkb:YBR0811(orf name)|uniprotkb:YBR088C(locus name)|uniprotkb:POL30(gene name)|psi-mi:POL30(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550556|imex:IM-24995-3210	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N	refseq:NP_009645.1|sgd:S000000292|go:"GO:0043626"(PCNA complex)|go:"GO:0070987"(error-free translesion synthesis)|go:"GO:1902394"(positive regulation of exodeoxyribonuclease activity)|go:"GO:1903022"(positive regulation of phosphodiesterase activity, acting on 3'-phosphoglycolate-terminated DNA strands)|go:"GO:1905779"(positive regulation of exonuclease activity)|interpro:IPR000730(Proliferating cell nuclear antigen, PCNA)|interpro:IPR022648|interpro:IPR022649|interpro:IPR022659|rcsb pdb:1PLQ|rcsb pdb:1PLR|rcsb pdb:1SXJ|rcsb pdb:2OD8|rcsb pdb:3F1W|rcsb pdb:3GPM|rcsb pdb:3GPN|rcsb pdb:3L0W|rcsb pdb:4L6P|rcsb pdb:3L0X|rcsb pdb:3L10|rcsb pdb:4YHR|rcsb pdb:3PGE|rcsb pdb:3V60|rcsb pdb:3V61|rcsb pdb:3V62|rcsb pdb:5JNE|rcsb pdb:4L60|mint:P15873|dip:DIP-2417N|go:"GO:0035753"(maintenance of DNA trinucleotide repeats)|ensemblfungi:YBR088C(gene)|ensemblfungi:YBR088C_mRNA(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000710"(meiotic mismatch repair)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005657"(replication fork)|go:"GO:0006272"(leading strand elongation)|go:"GO:0006273"(lagging strand elongation)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006298"(mismatch repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0006348"|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0019985"(translesion synthesis)|go:"GO:0030337"(DNA polymerase processivity factor activity)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0034087"(establishment of mitotic sister chromatid cohesion)|go:"GO:0042802"(identical protein binding)|rcsb pdb:5T9D|rcsb pdb:5V7K|rcsb pdb:5V7M|rcsb pdb:5ZUT|rcsb pdb:6CX2|rcsb pdb:6CX3|rcsb pdb:6CX4|rcsb pdb:6D0Q|rcsb pdb:6D0R|rcsb pdb:6E49|rcsb pdb:6W9W|rcsb pdb:6WAC|reactome:R-SCE-110312|reactome:R-SCE-110320|reactome:R-SCE-4615885|reactome:R-SCE-5358565|reactome:R-SCE-5655862|reactome:R-SCE-5656121|reactome:R-SCE-5656169|reactome:R-SCE-6782135|reactome:R-SCE-69091|reactome:R-SCE-69166|reactome:R-SCE-69183|reactome:R-SCE-8866654|rcsb pdb:5V7L	-	-	crc64:9B56C5851621DDDC	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	rogid:/+XSPV99OBBwBBC/nY0JiHaAeSI559292	intact-crc:771956E87C17EEFE|rigid:YdniTwKdzx3mimAIA3uHlEvBwf0	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P25354	uniprotkb:P63279	intact:EBI-21848|uniprotkb:Q70DH1|uniprotkb:Q70DH4|uniprotkb:Q70DH6|uniprotkb:D6VR16|ensemblfungi:YCR007C	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	psi-mi:ycp7_yeast(display_long)|uniprotkb:YCR045(orf name)|uniprotkb:YCR7C(orf name)|uniprotkb:YCR007C(locus name)	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550580|imex:IM-24995-3216	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009933.1|sgd:S000000600|dip:DIP-4043N|ensemblfungi:YCR007C(gene)|ensemblfungi:YCR007C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|interpro:IPR001142(Yeast membrane protein DUP)	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:5AYWvsKbIkyI0AaAP811MKfdVXI559292	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	intact-crc:85683C3A01F57DEC|rigid:R1WRsBaowNpKKdpBR0jtU7mUOMU	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P63279	uniprotkb:P32562	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	intact:EBI-4440|ensemblfungi:YMR001C|uniprotkb:D6VZH5	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:cdc5_yeast(display_long)|uniprotkb:CDC5(gene name)|psi-mi:CDC5(display_short)|uniprotkb:MSD2(gene name synonym)|uniprotkb:PKX2(gene name synonym)|uniprotkb:YMR001C(locus name)|uniprotkb:YM8270.03C(orf name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550564|imex:IM-24995-3212	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N	ensemblfungi:YMR001C(gene)|ensemblfungi:YMR001C_mRNA(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0000922"(spindle pole)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0010458"(exit from mitosis)|go:"GO:0010696"(positive regulation of mitotic spindle pole body separation)|go:"GO:0019237"(centromeric DNA binding)|refseq:NP_013714.1|sgd:S000004603|reactome:R-SCE-6804115|reactome:R-SCE-156711|reactome:R-SCE-162658|reactome:R-SCE-2565942|dip:DIP-2321N|reactome:R-SCE-2500257|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0035025"(positive regulation of Rho protein signal transduction)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051301"(cell division)|go:"GO:0070194"(synaptonemal complex disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0110083"(positive regulation of protein localization to cell division site involved in mitotic actomyosin contractile ring assembly)|go:"GO:1902542"(regulation of protein localization to mitotic spindle pole body)|go:"GO:1903353"(regulation of nucleus organization)|go:"GO:1904750"(negative regulation of protein localization to nucleolus)|go:"GO:1905339"(positive regulation of cohesin unloading)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033695|interpro:IPR033701|interpro:IPR036947|rcsb pdb:6MF4|rcsb pdb:6MF5|rcsb pdb:6MF6	-	-	crc64:B5A25F1BBBEAA3DC	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	rogid:XXSkltYvBA9Zkh0Kr5s1znazUC0559292	intact-crc:6AD9928B0589794C|rigid:ko/lk8jigrCH06sKQuyEbR2AXj4	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P63279	intact:EBI-11522346	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	-	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:ctt1(display_short)|psi-mi:EBI-11522346(display_long)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550572|imex:IM-24995-3214	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N	-	-	-	no-uniprot-update:	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	rogid:jNEGATUEb58kyyOUWh6Xi7tJTk04932	intact-crc:6DA6E3991A087D8F|rigid:ZzCTm/J4wYAeXTuzTojCTEMWyUo	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P63279	uniprotkb:P33417	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	intact:EBI-9401|ensemblfungi:YKL032C|uniprotkb:D6VXQ4	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:ixr1_yeast(display_long)|uniprotkb:IXR1(gene name)|psi-mi:IXR1(display_short)|uniprotkb:ORD1(gene name synonym)|uniprotkb:YKL032C(locus name)|uniprotkb:YKL245(orf name)|uniprotkb:Structure-specific recognition protein(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550568|imex:IM-24995-3213	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N	ensemblfungi:YKL032C(gene)|ensemblfungi:YKL032C_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0072718"(response to cisplatin)|go:"GO:0090069"(regulation of ribosome biogenesis)|go:"GO:2000819"(regulation of nucleotide-excision repair)|go:"GO:0005634"(nucleus)|reactome:R-SCE-5620971|reactome:R-SCE-5686938|reactome:R-SCE-6798695|sgd:S000001515|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR036910|refseq:NP_012893.3|interpro:IPR033311|reactome:R-SCE-140342	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	rogid:owYbshNfmIe1+4PkRItBvAQ2GN0559292	intact-crc:C45B48EC4AA5B817|rigid:1+ptW9qqRSPyAxtnJ7cZhUVrGeQ	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P63279	uniprotkb:P53176	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	intact:EBI-6205|uniprotkb:D6VU89|ensemblfungi:YGL051W	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:mst27_yeast(display_long)|uniprotkb:MST27(gene name)|psi-mi:MST27(display_short)|uniprotkb:DUP2(gene name synonym)|uniprotkb:DUP240 protein MST27(gene name synonym)|uniprotkb:YGL051W(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550576|imex:IM-24995-3215	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N	sgd:S000003019|refseq:NP_011464.1|dip:DIP-1852N|ensemblfungi:YGL051W(gene)|ensemblfungi:YGL051W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030663"(COPI-coated vesicle membrane)|interpro:IPR001142(Yeast membrane protein DUP)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	rogid:Vt2rgCK0Q+Ia3/1xU5hD7i+OCvg559292	intact-crc:C2D72FD195139811|rigid:EDMg/R5oMoO1sTMuoldYSwH7pR4	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P69851	uniprotkb:Q7Z6G3-2	intact:EBI-975389|uniprotkb:D6VSV2|ensemblfungi:YDR320C-A	intact:EBI-10172876|ensembl:ENSP00000457354|intact:EBI-14062040	psi-mi:dad4_yeast(display_long)|uniprotkb:Outer kinetochore protein DAD4(gene name synonym)|uniprotkb:DUO1 and DAM1-interacting protein 4(gene name synonym)|uniprotkb:Helper of ASK1 protein 2(gene name synonym)|uniprotkb:DAD4(gene name)|psi-mi:DAD4(display_short)|uniprotkb:HSK2(gene name synonym)|uniprotkb:YDR320C-A(locus name)	psi-mi:q7z6g3-2(display_long)|uniprotkb:EFCBP2(gene name synonym)|uniprotkb:Neuronal calcium-binding protein 2(gene name synonym)|uniprotkb:Synaptotagmin-interacting protein 2(gene name synonym)|uniprotkb:NECAB2(gene name)|psi-mi:NECAB2(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550608|imex:IM-24995-3223	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YDR320C-A(gene)|ensemblfungi:YDR320C-A_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0008608"(attachment of spindle microtubules to kinetochore)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0042729"(DASH complex)|go:"GO:0051301"(cell division)|go:"GO:0051987"(positive regulation of attachment of spindle microtubules to kinetochore)|go:"GO:0072686"(mitotic spindle)|sgd:S000007604|interpro:IPR013959(DASH complex, subunit Dad4)|refseq:NP_710144.3|mint:P69851	ensembl:ENSG00000103154(gene)|ensembl:ENST00000565691(transcript)|uniprotkb:Q7Z6G3-2(isoform-parent)|intact:EBI-950070(isoform-parent)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:P+GXHuoP14//+W2vOt26MEdTBNo559292	rogid:4S7oIx6h+mKzV3EPxqcfMNqaNko9606	intact-crc:CC6B7BCC6B3C4F26|rigid:XeYySTq6AMDc79CirC718x56X1k	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P63279	uniprotkb:P25453	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	intact:EBI-5955|uniprotkb:D3DM88|ensemblfungi:YER179W	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:dmc1_yeast(display_long)|uniprotkb:YER179W(locus name)|uniprotkb:DMC1(gene name)|psi-mi:DMC1(display_short)|uniprotkb:ISC2(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550604|imex:IM-24995-3222	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N	refseq:NP_011106.1|sgd:S000000981|dip:DIP-110N|mint:P25453|ensemblfungi:YER179W(gene)|ensemblfungi:YER179W_mRNA(transcript)|go:"GO:0000150"(DNA strand exchange activity)|go:"GO:0000709"(meiotic joint molecule formation)|go:"GO:0000730"(DNA recombinase assembly)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006312"(mitotic recombination)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0030435"(sporulation resulting in formation of a cellular spore)|go:"GO:0042030"(ATPase inhibitor activity)|go:"GO:0042148"(strand invasion)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070192"(chromosome organization involved in meiotic cell cycle)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010995(DNA repair Rad51/transcription factor NusA, alpha-helical)|interpro:IPR011940(Meiotic recombinase Dmc1)|interpro:IPR013632(Rad51, C-terminal)|interpro:IPR016467(DNA repair and recombination, RecA-like)|interpro:IPR020587|interpro:IPR020588|interpro:IPR027417|interpro:IPR033925	-	-	crc64:00B0503D7FAF5CB3	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	rogid:tbn7/STS08gIJBzfUmIz/yPmBJ8559292	intact-crc:65AA4CA42FCDFF6A|rigid:3bEIEs4jkQOFMJU/UEvB+mRwNfU	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P53243	uniprotkb:P63279	intact:EBI-23197|uniprotkb:D6VUK1|ensemblfungi:YGR067C	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	psi-mi:yg2a_yeast(display_long)|uniprotkb:YGR067C(locus name)	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550600|imex:IM-24995-3221	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003299|refseq:NP_011581.4|dip:DIP-2819N|mint:P53243|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|ensemblfungi:YGR067C(gene)|ensemblfungi:YGR067C_mRNA(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N	-	crc64:BB936C265B7B263F	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:/qkApijbHr7FKeeSJZ6IczHMf28559292	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	intact-crc:ECDDE19B371C4578|rigid:/jZIwuU3SbqWcHtgYxohgylsdM8	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P49723	uniprotkb:P63279	intact:EBI-15251|uniprotkb:Q66R92|uniprotkb:D6VUW4|ensemblfungi:YGR180C	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	psi-mi:rir4_yeast(display_long)|uniprotkb:RNR4(gene name)|psi-mi:RNR4(display_short)|uniprotkb:YGR180C(locus name)|uniprotkb:CRT3(gene name synonym)|uniprotkb:Ribonucleotide reductase small subunit 2(gene name synonym)|uniprotkb:Ribonucleotide reductase R2 subunit 2(gene name synonym)	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550584|imex:IM-24995-3217	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003412|refseq:NP_011696.3|ensemblfungi:YGR180C(gene)|ensemblfungi:YGR180C_mRNA(transcript)|go:"GO:0004748"(ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005971"(ribonucleoside-diphosphate reductase complex)|go:"GO:0006260"(DNA replication)|go:"GO:0009263"(deoxyribonucleotide biosynthetic process)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR000358(Ribonucleotide reductase)|interpro:IPR012348(Ribonucleotide reductase-related)|interpro:IPR030475|interpro:IPR033909|rcsb pdb:1JK0|rcsb pdb:1SMS|rcsb pdb:1ZZD|interpro:IPR009078(Ferritin/ribonucleotide reductase-like)|dip:DIP-5381N|mint:P49723	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N	-	crc64:712853F2D87D3972	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:/Mx5xMzGpJSBsCDX8nwJMacQ6d4559292	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	intact-crc:A09300A152B664E2|rigid:B30fmCZAgY+r6nzkEimWDZSwJr8	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P63279	uniprotkb:P46985	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	intact:EBI-11052|uniprotkb:E9P8Z0|ensemblfungi:YJL183W|uniprotkb:D6VW07	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:mnn11_yeast(display_long)|uniprotkb:MNN11(gene name)|psi-mi:MNN11(display_short)|uniprotkb:YJL183W(locus name)|uniprotkb:J0425(orf name)|uniprotkb:Mannan polymerase II complex MNN11 subunit(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550592|imex:IM-24995-3219	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N	ensemblfungi:YJL183W(gene)|ensemblfungi:YJL183W_mRNA(transcript)|go:"GO:0000009"(alpha-1,6-mannosyltransferase activity)|go:"GO:0000032"(cell wall mannoprotein biosynthetic process)|go:"GO:0000136"(mannan polymerase complex)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006487"(protein N-linked glycosylation)|interpro:IPR008630(Galactosyl transferase)|interpro:IPR029044|go:"GO:0000139"(Golgi membrane)|refseq:NP_012352.2|sgd:S000003719|dip:DIP-914N	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	rogid:JInEivytHOK2ZvKHg1LamaaIR70559292	intact-crc:071EECADCA3CF1AF|rigid:BC7/cijqzTCyCeVyp5im1PNdh/w	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P63279	uniprotkb:P38991	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	intact:EBI-9319|ensemblfungi:YPL209C|uniprotkb:D6W3G1	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:ipl1_yeast(display_long)|uniprotkb:IPL1(gene name)|psi-mi:IPL1(display_short)|uniprotkb:YPL209C(locus name)|uniprotkb:Aurora kinase(gene name synonym)|uniprotkb:Increase-in-ploidy protein 1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550588|imex:IM-24995-3218	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N	ensemblfungi:YPL209C(gene)|ensemblfungi:YPL209C_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005828"(kinetochore microtubule)|go:"GO:0005874"(microtubule)|go:"GO:0005876"(spindle microtubule)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008608"(attachment of spindle microtubules to kinetochore)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0032133"(chromosome passenger complex)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0035174"(histone serine kinase activity)|go:"GO:0044774"(mitotic DNA integrity checkpoint signaling)|go:"GO:0045143"(homologous chromosome segregation)|go:"GO:0045144"(meiotic sister chromatid segregation)|go:"GO:0051228"(mitotic spindle disassembly)|go:"GO:0051233"(spindle midzone)|go:"GO:0090266"(regulation of mitotic cell cycle spindle assembly checkpoint)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901673"(regulation of mitotic spindle assembly)|go:"GO:1901925"(negative regulation of protein import into nucleus during spindle assembly checkpoint)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR030616|reactome:R-SCE-8854050|refseq:NP_015115.1|sgd:S000006130|dip:DIP-2771N|mint:P38991	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	rogid:hNg/pnDWxuP6BSpguV7aFh50wtE559292	intact-crc:D1573FB12548E704|rigid:6iS+zoUtLDyAWkBXjVkV2AjXdmg	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P60010	uniprotkb:P63279	intact:EBI-2169|uniprotkb:P02579|uniprotkb:Q9P3X6|uniprotkb:Q9P3X7|uniprotkb:D6VTJ1|ensemblfungi:YFL039C	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	psi-mi:act_yeast(display_long)|uniprotkb:ACT1(gene name)|psi-mi:ACT1(display_short)|uniprotkb:ABY1(gene name synonym)|uniprotkb:END7(gene name synonym)|uniprotkb:YFL039C(locus name)	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550596|imex:IM-24995-3220	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_116614.1|sgd:S000001855|dip:DIP-310N|mint:P60010|ensemblfungi:YFL039C(gene)|ensemblfungi:YFL039C_mRNA(transcript)|go:"GO:0000011"(vacuole inheritance)|go:"GO:0000142"(cellular bud neck contractile ring)|go:"GO:0000812"(Swr1 complex)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005524"(ATP binding)|go:"GO:0005884"(actin filament)|go:"GO:0006281"(DNA repair)|go:"GO:0006897"(endocytosis)|go:"GO:0009306"(protein secretion)|go:"GO:0016573"(histone acetylation)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030476"(ascospore wall assembly)|go:"GO:0030479"(actin cortical patch)|go:"GO:0031011"(Ino80 complex)|go:"GO:0032432"(actin filament bundle)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:1902404"(mitotic actomyosin contractile ring contraction)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|rcsb pdb:1YAG|rcsb pdb:1YVN|rcsb pdb:5NBL|rcsb pdb:5NBM|rcsb pdb:5NBN|rcsb pdb:5Y81|reactome:R-SCE-114608|reactome:R-SCE-190873|reactome:R-SCE-196025|reactome:R-SCE-2029482|reactome:R-SCE-5626467|reactome:R-SCE-5663213|reactome:R-SCE-8856828|reactome:R-SCE-8980692|reactome:R-SCE-9013026	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N	-	crc64:87AC19B0B0BC9E71	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:yfgwiWq/Y0HviACqgjjUugpEKLw559292	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	intact-crc:635B02D550F0C39F|rigid:19emcZCbYXAS9jiEmSlPqcW4P9M	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P98170	uniprotkb:P38340	intact:EBI-517127|uniprotkb:Q9NQ14|uniprotkb:D3DTF2|ensembl:ENSP00000347858|ensembl:ENSP00000360242|ensembl:ENSP00000395230	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:xiap_human(display_long)|uniprotkb:Inhibitor of apoptosis protein 3(gene name synonym)|uniprotkb:X-linked inhibitor of apoptosis protein(gene name synonym)|uniprotkb:IAP-like protein(gene name synonym)|uniprotkb:XIAP(gene name)|psi-mi:XIAP(display_short)|uniprotkb:API3(gene name synonym)|uniprotkb:IAP3(gene name synonym)|uniprotkb:BIRC4(gene name synonym)|uniprotkb:Baculoviral IAP repeat-containing protein 4(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase XIAP(gene name synonym)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550632|imex:IM-24995-3229	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006724817.1|refseq:NP_001158.2|refseq:NP_001191330.1|refseq:XP_011529631.1|dip:DIP-27626N|ensembl:ENSG00000101966(gene)|ensembl:ENST00000355640(transcript)|ensembl:ENST00000371199(transcript)|ensembl:ENST00000434753(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005876"(spindle microtubule)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030510"(regulation of BMP signaling pathway)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0055070"(copper ion homeostasis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070424"(regulation of nucleotide-binding oligomerization domain containing signaling pathway)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:1902530"(positive regulation of protein linear polyubiquitination)|go:"GO:1990001"(inhibition of cysteine-type endopeptidase activity involved in apoptotic process)|interpro:IPR001370(Proteinase inhibitor I32, inhibitor of apoptosis)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011029(DEATH-like)|interpro:IPR042579|mint:P98170|rcsb pdb:1C9Q|rcsb pdb:1F9X|rcsb pdb:1G3F|rcsb pdb:1G73|rcsb pdb:1I3O|rcsb pdb:1I4O|rcsb pdb:1I51|rcsb pdb:1KMC|rcsb pdb:1NW9|rcsb pdb:1TFQ|rcsb pdb:1TFT|rcsb pdb:2ECG|rcsb pdb:2JK7|rcsb pdb:2KNA|rcsb pdb:2OPY|rcsb pdb:2OPZ|rcsb pdb:2POI|rcsb pdb:2POP|rcsb pdb:2QRA|rcsb pdb:2VSL|rcsb pdb:3CLX|rcsb pdb:3CM2|rcsb pdb:3CM7|rcsb pdb:3EYL|rcsb pdb:3G76|rcsb pdb:3HL5|rcsb pdb:3UW4|rcsb pdb:3UW5|rcsb pdb:4EC4|rcsb pdb:4HY0|rcsb pdb:4IC2|rcsb pdb:4IC3|rcsb pdb:4J3Y|rcsb pdb:4J44|rcsb pdb:4J45|rcsb pdb:4J46|rcsb pdb:4J47|rcsb pdb:4J48|rcsb pdb:4KJU|rcsb pdb:4KJV|rcsb pdb:4KMP|rcsb pdb:4MTZ|rcsb pdb:4OXC|rcsb pdb:4WVS|rcsb pdb:4WVT|rcsb pdb:4WVU|rcsb pdb:5C0K|rcsb pdb:5C0L|rcsb pdb:5C3H|rcsb pdb:5C3K|rcsb pdb:5C7A|rcsb pdb:5C7B|rcsb pdb:5C7C|rcsb pdb:5C7D|rcsb pdb:5C83|rcsb pdb:5C84|rcsb pdb:5M6E|rcsb pdb:5M6F|rcsb pdb:5M6H|rcsb pdb:5M6L|rcsb pdb:5M6M|rcsb pdb:5O6T|rcsb pdb:5OQW|rcsb pdb:6EY2|rcsb pdb:6GJW|rcsb pdb:6QCI|reactome:R-HSA-111459|reactome:R-HSA-111463|reactome:R-HSA-111464|reactome:R-HSA-111469|reactome:R-HSA-3769402|reactome:R-HSA-5213460|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5675482|reactome:R-HSA-8948747|reactome:R-HSA-8948751|reactome:R-HSA-9627069	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F	-	-	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:6eDcOay+c2ZmIAD/pwnCDROBwgM9606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:0A97AECE4181BCC8|rigid:hKpSWqBZNFklBmgvmQu7TjwTT2Y	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P89886	uniprotkb:O43583	intact:EBI-33141|uniprotkb:D3DLQ4|ensemblfungi:YER007C-A	intact:EBI-716083|uniprotkb:Q9H3U6|uniprotkb:Q9UKZ0|ensembl:ENSP00000280557	psi-mi:tma20_yeast(display_long)|uniprotkb:TMA20(gene name)|psi-mi:TMA20(display_short)|uniprotkb:YER007C-A(locus name)	psi-mi:denr_human(display_long)|uniprotkb:Protein DRP1(gene name synonym)|uniprotkb:Smooth muscle cell-associated protein 3(gene name synonym)|uniprotkb:DENR(gene name)|psi-mi:DENR(display_short)|uniprotkb:DRP1(gene name synonym)|uniprotkb:H14(orf name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550628|imex:IM-24995-3228	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002957|refseq:NP_010923.3|mint:P89886|dip:DIP-1841N|ensemblfungi:YER007C-A(gene)|ensemblfungi:YER007C-A_mRNA(transcript)|go:"GO:0001731"(formation of translation preinitiation complex)|go:"GO:0002188"(translation reinitiation)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0042254"(ribosome biogenesis)|interpro:IPR002478(PUA)|interpro:IPR004521(Uncharacterized domain 2)|interpro:IPR015947(PUA-like)|interpro:IPR016437(Translation machinery-associated RNA binding protein, predicted)|interpro:IPR041366	refseq:NP_003668.2|go:"GO:0075522"(IRES-dependent viral translational initiation)|interpro:IPR001950(Translation initiation factor SUI1)|interpro:IPR005873(Density-regulated protein DRP1)|interpro:IPR036877|go:"GO:0032790"(ribosome disassembly)|mint:O43583|rcsb pdb:5ONS|rcsb pdb:5VYC|rcsb pdb:6MS4|rcsb pdb:6VPQ|rcsb pdb:6VPR|ensembl:ENSG00000139726(gene)|ensembl:ENST00000280557(transcript)|go:"GO:0001731"(formation of translation preinitiation complex)|go:"GO:0002188"(translation reinitiation)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:vBHXl1594jcHQvXHu/MCy4G6U4c559292	rogid:pZLEnnYWNEai+gZ/jD+Rt9B6j2E9606	intact-crc:0F274595F36C1497|rigid:lI9/Vn8gtSU8OSadw26o/6OpIBo	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P47086	uniprotkb:P78356-2	intact:EBI-26299|uniprotkb:D6VWI7|uniprotkb:Q6Q5N5|ensemblfungi:YJR011C	intact:EBI-11532361	psi-mi:yjy1_yeast(display_long)|uniprotkb:J1438(orf name)|uniprotkb:YJR83.26(orf name)|uniprotkb:YJR011C(locus name)	psi-mi:p78356-2(display_long)|uniprotkb:PIP4K2B(gene name)|psi-mi:PIP4K2B(display_short)|uniprotkb:1-phosphatidylinositol 5-phosphate 4-kinase 2-beta(gene name synonym)|uniprotkb:Diphosphoinositide kinase 2-beta(gene name synonym)|uniprotkb:PIP5K2B(gene name synonym)|uniprotkb:Phosphatidylinositol 5-phosphate 4-kinase type II beta(gene name synonym)|uniprotkb:"PtdIns(5)P-4-kinase isoform 2-beta"(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550612|imex:IM-24995-3224	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003772|refseq:NP_012545.1|mint:P47086|dip:DIP-5694N|ensemblfungi:YJR011C(gene)|ensemblfungi:YJR011C_mRNA(transcript)	intact:EBI-947090(isoform-parent)|uniprotkb:P78356-2(isoform-parent)	-	-	isoform-comment:No experimental confirmation available.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:b7YXohJEN6FMN8gYKAKboZQkxvQ559292	rogid:vM046yHfiRTiHTWlLYpaqEegf0o9606	intact-crc:6DAA7D382A7ECC6D|rigid:u9P+H3Bj4VVQyFi4wgifyu5XH0g	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P81877	uniprotkb:P20081	intact:EBI-748077|uniprotkb:Q8N2Q2|uniprotkb:Q9BWW6|uniprotkb:Q9Y4T7|uniprotkb:B7Z2L9|uniprotkb:E9PDA8|uniprotkb:B2R5W1|uniprotkb:B7Z1J2|uniprotkb:B7Z665|uniprotkb:D6RH18|uniprotkb:E9PB74|intact:EBI-28967061|ensembl:ENSP00000322977	intact:EBI-6961|uniprotkb:D6W147|ensemblfungi:YNL135C	psi-mi:ssbp2_human(display_long)|uniprotkb:Sequence-specific single-stranded-DNA-binding protein 2(gene name synonym)|uniprotkb:SSBP2(gene name)|psi-mi:SSBP2(display_short)|uniprotkb:SSDP2(gene name synonym)	psi-mi:fkbp_yeast(display_long)|uniprotkb:RBP1(gene name synonym)|uniprotkb:N1213(orf name)|uniprotkb:N1845(orf name)|uniprotkb:YNL135C(locus name)|uniprotkb:FPR1(gene name)|psi-mi:FPR1(display_short)|uniprotkb:FKB1(gene name synonym)|uniprotkb:Peptidyl-prolyl cis-trans isomerase(gene name synonym)|uniprotkb:Rapamycin-binding protein(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550620|imex:IM-24995-3226	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000322977|ensembl:ENST00000505980|ensembl:ENSP00000423969|ensembl:ENST00000509053|ensembl:ENSP00000422961|ensembl:ENST00000514493|ensembl:ENSP00000426183|ensembl:ENST00000515395|ensembl:ENSP00000424657|refseq:NP_001243661.1|refseq:NP_036578.2|refseq:NP_001243665.1|refseq:NP_001243663.1|refseq:NP_001243664.1|refseq:NP_001243662.1|ensembl:ENSG00000145687(gene)|ensembl:ENST00000320672(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR008116(Sequence-specific single-strand DNA-binding protein)|mint:P81877|rcsb pdb:6IWV|rcsb pdb:6TYD|dip:DIP-29459N	refseq:NP_014264.1|sgd:S000005079|dip:DIP-1263N|mint:P20081|ensemblfungi:YNL135C(gene)|ensemblfungi:YNL135C_mRNA(transcript)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005527"(macrolide binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006325"(chromatin organization)|go:"GO:0006457"(protein folding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:1901710"(regulation of homoserine biosynthetic process)|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)|rcsb pdb:1YAT	-	-	crc64:65C134830D300C06	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:CMmZPTurp1G6Y2q7GP/pTMlFM549606	rogid:8afvGSk+mPghtqkVoWd2rHJXXhQ559292	intact-crc:15687C353EE9324F|rigid:uZJRlMh9x8XnKjRL2xHC18tthvk	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P40454	uniprotkb:P81877	intact:EBI-25278|uniprotkb:D6VVD4|ensemblfungi:YIL153W	intact:EBI-748077|uniprotkb:Q8N2Q2|uniprotkb:Q9BWW6|uniprotkb:Q9Y4T7|uniprotkb:B7Z2L9|uniprotkb:E9PDA8|uniprotkb:B2R5W1|uniprotkb:B7Z1J2|uniprotkb:B7Z665|uniprotkb:D6RH18|uniprotkb:E9PB74|intact:EBI-28967061|ensembl:ENSP00000322977	psi-mi:ptpa1_yeast(display_long)|uniprotkb:YIL153W(locus name)|uniprotkb:RRD1(gene name)|psi-mi:RRD1(display_short)|uniprotkb:NCS1(gene name synonym)|uniprotkb:YPA1(gene name synonym)|uniprotkb:Peptidyl-prolyl cis-trans isomerase PTPA-1(gene name synonym)|uniprotkb:Phosphotyrosyl phosphatase activator 1(gene name synonym)	psi-mi:ssbp2_human(display_long)|uniprotkb:Sequence-specific single-stranded-DNA-binding protein 2(gene name synonym)|uniprotkb:SSBP2(gene name)|psi-mi:SSBP2(display_short)|uniprotkb:SSDP2(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550616|imex:IM-24995-3225	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012113.1|sgd:S000001415|mint:P40454|dip:DIP-5663N|ensemblfungi:YIL153W(gene)|ensemblfungi:YIL153W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006914"(autophagy)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008160"(protein tyrosine phosphatase activator activity)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0043618"(regulation of transcription from RNA polymerase II promoter in response to stress)|interpro:IPR004327(Phosphotyrosyl phosphatase activator, PTPA)|interpro:IPR037218|interpro:IPR043170|rcsb pdb:2IXO|rcsb pdb:2IXP	ensembl:ENSP00000322977|ensembl:ENST00000505980|ensembl:ENSP00000423969|ensembl:ENST00000509053|ensembl:ENSP00000422961|ensembl:ENST00000514493|ensembl:ENSP00000426183|ensembl:ENST00000515395|ensembl:ENSP00000424657|refseq:NP_001243661.1|refseq:NP_036578.2|refseq:NP_001243665.1|refseq:NP_001243663.1|refseq:NP_001243664.1|refseq:NP_001243662.1|ensembl:ENSG00000145687(gene)|ensembl:ENST00000320672(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR008116(Sequence-specific single-strand DNA-binding protein)|mint:P81877|rcsb pdb:6IWV|rcsb pdb:6TYD|dip:DIP-29459N	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:It2q8WlpmvLEZ1fqpRF5Fypw9Q4559292	rogid:CMmZPTurp1G6Y2q7GP/pTMlFM549606	intact-crc:4013140DDA1E5012|rigid:GhV/GnLYK6m7wnyOqY+K5wXl64s	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P43356	uniprotkb:P87108	intact:EBI-5650739|uniprotkb:A8K328|uniprotkb:Q32NC6|ensembl:ENSP00000333487|ensembl:ENSP00000359316|ensembl:ENSP00000469919|ensembl:ENSP00000470872|ensembl:ENSP00000480491|ensembl:ENSP00000480738|ensembl:ENSP00000484290|ensembl:ENSP00000485391|ensembl:ENSP00000485541|ensembl:ENSP00000507594|ensembl:ENSP00000507899	intact:EBI-9115|ensemblfungi:YHR005C-A|uniprotkb:D3DKU9	psi-mi:maga2_human(display_long)|uniprotkb:MAGEA2(gene name)|psi-mi:MAGEA2(display_short)|uniprotkb:MAGEA2B(gene name)|psi-mi:MAGEA2B(display_short)|uniprotkb:MAGE2(gene name synonym)|uniprotkb:MAGEA2A(gene name synonym)|uniprotkb:MAGE2(gene name synonym)|uniprotkb:MAGEA2(gene name synonym)|uniprotkb:Cancer/testis antigen 1.2(gene name synonym)|uniprotkb:MAGE-2 antigen(gene name synonym)	psi-mi:tim10_yeast(display_long)|uniprotkb:MRS11(gene name synonym)|uniprotkb:YHR005BC(orf name)|uniprotkb:YHR005C-A(locus name)|uniprotkb:TIM10(gene name)|psi-mi:TIM10(display_short)|uniprotkb:Mitochondrial intermembrane protein MRS11(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550624|imex:IM-24995-3227	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001269430.1|refseq:NP_001269431.1|refseq:NP_001269433.1|refseq:NP_001269434.1|refseq:NP_001308329.1|refseq:NP_001308330.1|refseq:NP_001308331.1|refseq:NP_001308332.1|refseq:NP_001308333.1|refseq:NP_005352.1|refseq:NP_705692.1|refseq:NP_786884.1|refseq:NP_786885.1|dip:DIP-61231N|refseq:XP_016884895.1|refseq:XP_016885008.1|ensembl:ENSG00000183305(gene)|ensembl:ENSG00000268606(gene)|ensembl:ENST00000331220(transcript)|ensembl:ENST00000370293(transcript)|ensembl:ENST00000595583(transcript)|ensembl:ENST00000598543(transcript)|ensembl:ENST00000611557(transcript)|ensembl:ENST00000611674(transcript)|ensembl:ENST00000620710(transcript)|ensembl:ENST00000623438(transcript)|ensembl:ENST00000623806(transcript)|ensembl:ENST00000682532(transcript)|ensembl:ENST00000684311(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0016605"(PML body)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0033234"(negative regulation of protein sumoylation)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0044257"(cellular protein catabolic process)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0072331"(signal transduction by p53 class mediator)|go:"GO:0090398"(cellular senescence)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901984"(negative regulation of protein acetylation)|interpro:IPR002190(MAGE protein)|interpro:IPR021072|interpro:IPR030103|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899	ensemblfungi:YHR005C-A(gene)|ensemblfungi:YHR005C-A_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0042719"(mitochondrial intermembrane space protein transporter complex)|go:"GO:0045039"(protein insertion into mitochondrial inner membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0140318"(protein transporter activity)|interpro:IPR004217(Zinc finger, Tim10/DDP-type)|interpro:IPR027100|interpro:IPR035427|rcsb pdb:3DXR|rcsb pdb:6LO8|reactome:R-SCE-1268020|refseq:NP_011869.1|sgd:S000003530|dip:DIP-1141N|mint:P87108	-	-	crc64:70DD4764B944FF17	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:aYv4+irEk9vGE2f3yZQR8hCQGec9606	rogid:3AGstULCT5EBmHEk0EGsz9Rk9YA559292	intact-crc:4C8830024475223D|rigid:m2ZGLKKYf+pz/TOU270gTTuSVIU	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P38744	uniprotkb:Q02363	intact:EBI-13396|uniprotkb:D3DKR5|ensemblfungi:YHL018W	intact:EBI-713450|ensembl:ENSP00000234091|ensembl:ENSP00000379585|ensembl:ENSP00000385465	psi-mi:phs_yeast(display_long)|uniprotkb:4-alpha-hydroxy-tetrahydropterin dehydratase(gene name synonym)|uniprotkb:Pterin carbinolamine dehydratase(gene name synonym)|uniprotkb:YHL018W(locus name)	psi-mi:id2_human(display_long)|uniprotkb:Inhibitor of DNA binding 2(gene name synonym)|uniprotkb:ID2(gene name)|psi-mi:ID2(display_short)|uniprotkb:BHLHB26(gene name synonym)|uniprotkb:Class B basic helix-loop-helix protein 26(gene name synonym)|uniprotkb:Inhibitor of differentiation 2(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550660|imex:IM-24995-3236	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011845.1|sgd:S000001010|interpro:IPR036428|interpro:IPR001533(Transcriptional coactivator/pterin dehydratase)|ensemblfungi:YHL018W(gene)|ensemblfungi:YHL018W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0008124"(4-alpha-hydroxytetrahydrobiopterin dehydratase activity)|dip:DIP-1872N|reactome:R-SCE-8964208	ensembl:ENSG00000115738(gene)|ensembl:ENST00000234091(transcript)|ensembl:ENST00000331129(transcript)|ensembl:ENST00000396290(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000791"(euchromatin)|go:"GO:0003166"(bundle of His development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007507"(heart development)|go:"GO:0007623"(circadian rhythm)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0030154"(cell differentiation)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033598"(mammary gland epithelial cell proliferation)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0043353"(enucleate erythrocyte differentiation)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0045578"(negative regulation of B cell differentiation)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045651"(positive regulation of macrophage differentiation)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0045777"(positive regulation of blood pressure)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0048663"(neuron fate commitment)|go:"GO:0048711"(positive regulation of astrocyte differentiation)|go:"GO:0051148"(negative regulation of muscle cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0061030"(epithelial cell differentiation involved in mammary gland alveolus development)|go:"GO:0061031"(endodermal digestive tract morphogenesis)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0071931"(positive regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0090398"(cellular senescence)|go:"GO:0140416"(transcription regulator inhibitor activity)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000177"(regulation of neural precursor cell proliferation)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR026052|interpro:IPR036638|mint:Q02363|rcsb pdb:4AYA|reactome:R-HSA-9031628|refseq:NP_002157.2|dip:DIP-46874N	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:7+JuLX1wFw/tkE4NcSCTK62b4DU559292	rogid:zKX4mIq64fyS8DVPGQNeL7+c50w9606	intact-crc:462A0471CC3A6329|rigid:oNdc+G4sFcPRPhFkvBSc240INoY	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:G5E962	uniprotkb:Q01976	intact:EBI-11525615|ensembl:ENSP00000328177	intact:EBI-2344265|uniprotkb:D6VQB0|ensemblfungi:YBR111C	psi-mi:g5e962_human(display_long)|uniprotkb:hCG_1644200(orf name)|uniprotkb:MAGEA11(gene name)|psi-mi:MAGEA11(display_short)	psi-mi:adpp_yeast(display_long)|uniprotkb:YSA1(gene name)|psi-mi:YSA1(display_short)|uniprotkb:ADP-ribose diphosphatase(gene name synonym)|uniprotkb:Adenosine diphosphoribose pyrophosphatase(gene name synonym)|uniprotkb:ADP-ribose phosphohydrolase(gene name synonym)|uniprotkb:YBR0907(orf name)|uniprotkb:YBR111C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550656|imex:IM-24995-3235	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001011544.1|ensembl:ENSG00000185247(gene)|ensembl:ENST00000333104(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016604"(nuclear body)|interpro:IPR002190(MAGE protein)|interpro:IPR021072|interpro:IPR030099|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899	refseq:NP_009669.1|sgd:S000000315|interpro:IPR020084|interpro:IPR000086(NUDIX hydrolase, core)|interpro:IPR015797(NUDIX)|reactome:R-SCE-2393930|ensemblfungi:YBR111C(gene)|ensemblfungi:YBR111C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006753"(nucleoside phosphate metabolic process)|go:"GO:0019693"(ribose phosphate metabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0047631"(ADP-ribose diphosphatase activity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:sVB0aA6yibWUx/d2SE+pwpKKgtI9606	rogid:tpdVT9ttt/pL+UevSr0zW+rfyIc559292	intact-crc:1C94FA5C44BAD880|rigid:+oIfTL7Jn2G8+m/q4jryuXjkY8U	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P98170	uniprotkb:Q01976	intact:EBI-517127|uniprotkb:Q9NQ14|uniprotkb:D3DTF2|ensembl:ENSP00000347858|ensembl:ENSP00000360242|ensembl:ENSP00000395230	intact:EBI-2344265|uniprotkb:D6VQB0|ensemblfungi:YBR111C	psi-mi:xiap_human(display_long)|uniprotkb:Inhibitor of apoptosis protein 3(gene name synonym)|uniprotkb:X-linked inhibitor of apoptosis protein(gene name synonym)|uniprotkb:IAP-like protein(gene name synonym)|uniprotkb:XIAP(gene name)|psi-mi:XIAP(display_short)|uniprotkb:API3(gene name synonym)|uniprotkb:IAP3(gene name synonym)|uniprotkb:BIRC4(gene name synonym)|uniprotkb:Baculoviral IAP repeat-containing protein 4(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase XIAP(gene name synonym)	psi-mi:adpp_yeast(display_long)|uniprotkb:YSA1(gene name)|psi-mi:YSA1(display_short)|uniprotkb:ADP-ribose diphosphatase(gene name synonym)|uniprotkb:Adenosine diphosphoribose pyrophosphatase(gene name synonym)|uniprotkb:ADP-ribose phosphohydrolase(gene name synonym)|uniprotkb:YBR0907(orf name)|uniprotkb:YBR111C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550652|imex:IM-24995-3234	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006724817.1|refseq:NP_001158.2|refseq:NP_001191330.1|refseq:XP_011529631.1|dip:DIP-27626N|ensembl:ENSG00000101966(gene)|ensembl:ENST00000355640(transcript)|ensembl:ENST00000371199(transcript)|ensembl:ENST00000434753(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005876"(spindle microtubule)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030510"(regulation of BMP signaling pathway)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0055070"(copper ion homeostasis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070424"(regulation of nucleotide-binding oligomerization domain containing signaling pathway)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:1902530"(positive regulation of protein linear polyubiquitination)|go:"GO:1990001"(inhibition of cysteine-type endopeptidase activity involved in apoptotic process)|interpro:IPR001370(Proteinase inhibitor I32, inhibitor of apoptosis)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011029(DEATH-like)|interpro:IPR042579|mint:P98170|rcsb pdb:1C9Q|rcsb pdb:1F9X|rcsb pdb:1G3F|rcsb pdb:1G73|rcsb pdb:1I3O|rcsb pdb:1I4O|rcsb pdb:1I51|rcsb pdb:1KMC|rcsb pdb:1NW9|rcsb pdb:1TFQ|rcsb pdb:1TFT|rcsb pdb:2ECG|rcsb pdb:2JK7|rcsb pdb:2KNA|rcsb pdb:2OPY|rcsb pdb:2OPZ|rcsb pdb:2POI|rcsb pdb:2POP|rcsb pdb:2QRA|rcsb pdb:2VSL|rcsb pdb:3CLX|rcsb pdb:3CM2|rcsb pdb:3CM7|rcsb pdb:3EYL|rcsb pdb:3G76|rcsb pdb:3HL5|rcsb pdb:3UW4|rcsb pdb:3UW5|rcsb pdb:4EC4|rcsb pdb:4HY0|rcsb pdb:4IC2|rcsb pdb:4IC3|rcsb pdb:4J3Y|rcsb pdb:4J44|rcsb pdb:4J45|rcsb pdb:4J46|rcsb pdb:4J47|rcsb pdb:4J48|rcsb pdb:4KJU|rcsb pdb:4KJV|rcsb pdb:4KMP|rcsb pdb:4MTZ|rcsb pdb:4OXC|rcsb pdb:4WVS|rcsb pdb:4WVT|rcsb pdb:4WVU|rcsb pdb:5C0K|rcsb pdb:5C0L|rcsb pdb:5C3H|rcsb pdb:5C3K|rcsb pdb:5C7A|rcsb pdb:5C7B|rcsb pdb:5C7C|rcsb pdb:5C7D|rcsb pdb:5C83|rcsb pdb:5C84|rcsb pdb:5M6E|rcsb pdb:5M6F|rcsb pdb:5M6H|rcsb pdb:5M6L|rcsb pdb:5M6M|rcsb pdb:5O6T|rcsb pdb:5OQW|rcsb pdb:6EY2|rcsb pdb:6GJW|rcsb pdb:6QCI|reactome:R-HSA-111459|reactome:R-HSA-111463|reactome:R-HSA-111464|reactome:R-HSA-111469|reactome:R-HSA-3769402|reactome:R-HSA-5213460|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5675482|reactome:R-HSA-8948747|reactome:R-HSA-8948751|reactome:R-HSA-9627069	refseq:NP_009669.1|sgd:S000000315|interpro:IPR020084|interpro:IPR000086(NUDIX hydrolase, core)|interpro:IPR015797(NUDIX)|reactome:R-SCE-2393930|ensemblfungi:YBR111C(gene)|ensemblfungi:YBR111C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006753"(nucleoside phosphate metabolic process)|go:"GO:0019693"(ribose phosphate metabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0047631"(ADP-ribose diphosphatase activity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:6eDcOay+c2ZmIAD/pwnCDROBwgM9606	rogid:tpdVT9ttt/pL+UevSr0zW+rfyIc559292	intact-crc:0E05D83EE7785714|rigid:G4yBzu9FXOxAZj65iK+olxZAd+g	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P32502	uniprotkb:P98170	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	intact:EBI-517127|uniprotkb:Q9NQ14|uniprotkb:D3DTF2|ensembl:ENSP00000347858|ensembl:ENSP00000360242|ensembl:ENSP00000395230	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:xiap_human(display_long)|uniprotkb:Inhibitor of apoptosis protein 3(gene name synonym)|uniprotkb:X-linked inhibitor of apoptosis protein(gene name synonym)|uniprotkb:IAP-like protein(gene name synonym)|uniprotkb:XIAP(gene name)|psi-mi:XIAP(display_short)|uniprotkb:API3(gene name synonym)|uniprotkb:IAP3(gene name synonym)|uniprotkb:BIRC4(gene name synonym)|uniprotkb:Baculoviral IAP repeat-containing protein 4(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase XIAP(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550636|imex:IM-24995-3230	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731	refseq:XP_006724817.1|refseq:NP_001158.2|refseq:NP_001191330.1|refseq:XP_011529631.1|dip:DIP-27626N|ensembl:ENSG00000101966(gene)|ensembl:ENST00000355640(transcript)|ensembl:ENST00000371199(transcript)|ensembl:ENST00000434753(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005876"(spindle microtubule)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030510"(regulation of BMP signaling pathway)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0055070"(copper ion homeostasis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070424"(regulation of nucleotide-binding oligomerization domain containing signaling pathway)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:1902530"(positive regulation of protein linear polyubiquitination)|go:"GO:1990001"(inhibition of cysteine-type endopeptidase activity involved in apoptotic process)|interpro:IPR001370(Proteinase inhibitor I32, inhibitor of apoptosis)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011029(DEATH-like)|interpro:IPR042579|mint:P98170|rcsb pdb:1C9Q|rcsb pdb:1F9X|rcsb pdb:1G3F|rcsb pdb:1G73|rcsb pdb:1I3O|rcsb pdb:1I4O|rcsb pdb:1I51|rcsb pdb:1KMC|rcsb pdb:1NW9|rcsb pdb:1TFQ|rcsb pdb:1TFT|rcsb pdb:2ECG|rcsb pdb:2JK7|rcsb pdb:2KNA|rcsb pdb:2OPY|rcsb pdb:2OPZ|rcsb pdb:2POI|rcsb pdb:2POP|rcsb pdb:2QRA|rcsb pdb:2VSL|rcsb pdb:3CLX|rcsb pdb:3CM2|rcsb pdb:3CM7|rcsb pdb:3EYL|rcsb pdb:3G76|rcsb pdb:3HL5|rcsb pdb:3UW4|rcsb pdb:3UW5|rcsb pdb:4EC4|rcsb pdb:4HY0|rcsb pdb:4IC2|rcsb pdb:4IC3|rcsb pdb:4J3Y|rcsb pdb:4J44|rcsb pdb:4J45|rcsb pdb:4J46|rcsb pdb:4J47|rcsb pdb:4J48|rcsb pdb:4KJU|rcsb pdb:4KJV|rcsb pdb:4KMP|rcsb pdb:4MTZ|rcsb pdb:4OXC|rcsb pdb:4WVS|rcsb pdb:4WVT|rcsb pdb:4WVU|rcsb pdb:5C0K|rcsb pdb:5C0L|rcsb pdb:5C3H|rcsb pdb:5C3K|rcsb pdb:5C7A|rcsb pdb:5C7B|rcsb pdb:5C7C|rcsb pdb:5C7D|rcsb pdb:5C83|rcsb pdb:5C84|rcsb pdb:5M6E|rcsb pdb:5M6F|rcsb pdb:5M6H|rcsb pdb:5M6L|rcsb pdb:5M6M|rcsb pdb:5O6T|rcsb pdb:5OQW|rcsb pdb:6EY2|rcsb pdb:6GJW|rcsb pdb:6QCI|reactome:R-HSA-111459|reactome:R-HSA-111463|reactome:R-HSA-111464|reactome:R-HSA-111469|reactome:R-HSA-3769402|reactome:R-HSA-5213460|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5675482|reactome:R-HSA-8948747|reactome:R-HSA-8948751|reactome:R-HSA-9627069	-	crc64:A5409FAF1594854C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	rogid:6eDcOay+c2ZmIAD/pwnCDROBwgM9606	intact-crc:9D0607C2555D5753|rigid:LhvS0Fwa9VQ4GHPRulcrwvJqPig	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q00796	uniprotkb:P32502	intact:EBI-750068|uniprotkb:B2R655|uniprotkb:Q16682|uniprotkb:Q9UMD6|uniprotkb:B7Z3A6|uniprotkb:J3JZZ5|ensembl:ENSP00000267814	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:dhso_human(display_long)|uniprotkb:L-iditol 2-dehydrogenase(gene name synonym)|uniprotkb:SORD(gene name)|psi-mi:SORD(display_short)|uniprotkb:"(R,R)-butanediol dehydrogenase"(gene name synonym)|uniprotkb:Polyol dehydrogenase(gene name synonym)|uniprotkb:Ribitol dehydrogenase(gene name synonym)|uniprotkb:Xylitol dehydrogenase(gene name synonym)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550644|imex:IM-24995-3232	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003095.2|ensembl:ENSG00000140263(gene)|ensembl:ENST00000267814(transcript)|go:"GO:0000721"("(R,R)-butanediol dehydrogenase activity")|go:"GO:0003939"(L-iditol 2-dehydrogenase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006062"(sorbitol catabolic process)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009725"(response to hormone)|go:"GO:0016020"(membrane)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0031514"(motile cilium)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0046370"(fructose biosynthetic process)|go:"GO:0046526"(D-xylulose reductase activity)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0046688"(response to copper ion)|go:"GO:0050255"(ribitol 2-dehydrogenase activity)|go:"GO:0051160"(L-xylitol catabolic process)|go:"GO:0051164"(L-xylitol metabolic process)|go:"GO:0051287"(NAD binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002328(Alcohol dehydrogenase, zinc-containing, conserved site)|interpro:IPR011032(GroES-like)|interpro:IPR013149(Alcohol dehydrogenase, zinc-binding)|interpro:IPR013154(Alcohol dehydrogenase GroES-like)|interpro:IPR020843|interpro:IPR036291|mint:Q00796|rcsb pdb:1PL6|rcsb pdb:1PL7|rcsb pdb:1PL8|reactome:R-HSA-5652227|reactome:R-HSA-5661270	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731	-	-	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:BGqvXy2I7nmCLPYTOkUcQ8fpCkk9606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:B52E1E104E3258DE|rigid:WUFHFrW4kPfzg2PwNlplkSvfOcI	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O76083-2	uniprotkb:Q00618	intact:EBI-11524542|ensembl:ENSP00000335242	intact:EBI-3573|uniprotkb:D6VWF1|ensemblfungi:YJL031C	psi-mi:o76083-2(display_long)|uniprotkb:PDE9A(gene name)|psi-mi:PDE9A(display_short)	psi-mi:pgta_yeast(display_long)|uniprotkb:Geranylgeranyl transferase type II subunit alpha(gene name synonym)|uniprotkb:Type II protein geranyl-geranyltransferase subunit alpha(gene name synonym)|uniprotkb:PGGT(gene name synonym)|uniprotkb:YPT1/SEC4 proteins geranylgeranyltransferase subunit alpha(gene name synonym)|uniprotkb:GGTase-II-alpha(gene name synonym)|uniprotkb:BET4(gene name)|psi-mi:BET4(display_short)|uniprotkb:YJL031C(locus name)|uniprotkb:J1254(orf name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550640|imex:IM-24995-3231	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-742764(isoform-parent)|ensembl:ENSG00000160191(gene)|ensembl:ENST00000335512(transcript)|uniprotkb:O76083-2(isoform-parent)	refseq:NP_012503.2|sgd:S000003568|reactome:R-SCE-6803205|reactome:R-SCE-8873719|dip:DIP-4994N|ensemblfungi:YJL031C(gene)|ensemblfungi:YJL031C_mRNA(transcript)|go:"GO:0004663"(Rab geranylgeranyltransferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005777"(peroxisome)|go:"GO:0005829"(cytosol)|go:"GO:0005968"(Rab-protein geranylgeranyltransferase complex)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0018344"(protein geranylgeranylation)|go:"GO:0031267"(small GTPase binding)|interpro:IPR002088(Protein prenyltransferase, alpha subunit)|interpro:IPR032955	-	-	crc64:A7C3E16C14DDD09C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:nTzgeYGOwTM/7VJUgxSnlnDiCFo9606	rogid:xjJwfQovYxV3BOkX1NVrOXxq/PM559292	intact-crc:C4339D8323BA9613|rigid:w0s0D19GLkafzdPDwaSttgLhW14	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O95994	uniprotkb:Q01589	intact:EBI-712648|ensembl:ENSP00000391490	intact:EBI-16917|uniprotkb:D6VS63|uniprotkb:Q6Q5U8|uniprotkb:Q8J057|uniprotkb:Q8J270|uniprotkb:Q8J271|uniprotkb:Q8J272|uniprotkb:Q8J273|uniprotkb:Q8J274|uniprotkb:Q8J275|ensemblfungi:YDR077W	psi-mi:agr2_human(display_long)|uniprotkb:Secreted cement gland protein XAG-2 homolog(gene name synonym)|uniprotkb:HPC8(gene name synonym)|uniprotkb:AG2(gene name synonym)|uniprotkb:UNQ515/PRO1030(orf name)|uniprotkb:AGR2(gene name)|psi-mi:AGR2(display_short)	psi-mi:sed1_yeast(display_long)|uniprotkb:SED1(gene name)|psi-mi:SED1(display_short)|uniprotkb:YDR077W(locus name)|uniprotkb:D4431(orf name)|uniprotkb:Glycoprotein GP260(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550648|imex:IM-24995-3233	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005615"(extracellular space)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0042802"(identical protein binding)|go:"GO:0045742"(positive regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0048546"(digestive tract morphogenesis)|go:"GO:0048639"(positive regulation of developmental growth)|go:"GO:0060480"(lung goblet cell differentiation)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070254"(mucus secretion)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:1903896"(positive regulation of IRE1-mediated unfolded protein response)|go:"GO:1903899"(positive regulation of PERK-mediated unfolded protein response)|interpro:IPR036249|rcsb pdb:2LNS|rcsb pdb:2LNT|ensembl:ENSG00000106541(gene)|ensembl:ENST00000419304(transcript)|go:"GO:0002162"(dystroglycan binding)|go:"GO:0005154"(epidermal growth factor receptor binding)|refseq:NP_006399.1|refseq:XP_005249638.1|dip:DIP-48825N	refseq:NP_010362.3|sgd:S000002484|ensemblfungi:YDR077W(gene)|ensemblfungi:YDR077W_mRNA(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0005199"(structural constituent of cell wall)|go:"GO:0005576"(extracellular region)|go:"GO:0005739"(mitochondrion)|go:"GO:0005840"(ribosome)|go:"GO:0009277"(fungal-type cell wall)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0071944"(cell periphery)|interpro:IPR038843|dip:DIP-1613N	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:E824a1MDXuGzk23ohjS7HAeEx5U9606	rogid:4Oyb3fialIFuwCLzsRFRcTML3ng559292	intact-crc:9AB32AA4E8A955D2|rigid:+Og9Ak04gZMAOLZ+h81rO514dHk	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q02821	uniprotkb:P22234	intact:EBI-1797|uniprotkb:D6W0Z8|ensemblfungi:YNL189W	intact:EBI-712261|ensembl:ENSP00000264221|ensembl:ENSP00000421096|uniprotkb:E9PDH9|uniprotkb:Q68CQ5|intact:EBI-21352784	psi-mi:ima1_yeast(display_long)|uniprotkb:SRP1(gene name)|psi-mi:SRP1(display_short)|uniprotkb:KAP60(gene name synonym)|uniprotkb:YNL189W(locus name)|uniprotkb:N1606(orf name)|uniprotkb:Karyopherin subunit alpha(gene name synonym)|uniprotkb:Karyopherin-60(gene name synonym)|uniprotkb:Serine-rich RNA polymerase I suppressor protein(gene name synonym)	psi-mi:pur6_human(display_long)|uniprotkb:PAICS(gene name)|psi-mi:PAICS(display_short)|uniprotkb:ADE2(gene name synonym)|uniprotkb:AIRC(gene name synonym)|uniprotkb:PAIS(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550688|imex:IM-24995-3243	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014210.1|sgd:S000005133|dip:DIP-728N|mint:Q02821|ensemblfungi:YNL189W(gene)|ensemblfungi:YNL189W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0031144"(proteasome localization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042564"(NLS-dependent protein nuclear import complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|rcsb pdb:1BK5|rcsb pdb:1BK6|rcsb pdb:1EE4|rcsb pdb:1EE5|rcsb pdb:1UN0|rcsb pdb:1WA5|rcsb pdb:2C1T|rcsb pdb:4PVZ|rcsb pdb:4XZR|rcsb pdb:5H2W|rcsb pdb:5H2X|rcsb pdb:5T94	ensembl:ENSG00000128050(gene)|ensembl:ENST00000264221(transcript)|ensembl:ENST00000512576(transcript)|go:"GO:0004639"(phosphoribosylaminoimidazolesuccinocarboxamide synthase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006189"('de novo' IMP biosynthetic process)|go:"GO:0009113"(purine nucleobase biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043727"(5-amino-4-imidazole carboxylate lyase activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000031("1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase")|interpro:IPR018236|interpro:IPR028923|interpro:IPR033626|mint:P22234|rcsb pdb:2H31|rcsb pdb:6YB8|go:"GO:0004638"(phosphoribosylaminoimidazole carboxylase activity)|rcsb pdb:6YB9|reactome:R-HSA-73817|refseq:NP_001072992.1|refseq:NP_001072993.1|refseq:NP_006443.1	-	crc64:8D3A0CB76F2E7C00	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:NyzC93xnBCb8DX/AH346lwg4u2A559292	rogid:aR4Xj14ZQrPiY8cldw5o9AvjkAo9606	intact-crc:56237F1C561C75CC|rigid:XSq92qAfiIwgMiiBbsb5w5CSRFU	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P10823	uniprotkb:Q02818	intact:EBI-7382|uniprotkb:D3DLR9|ensemblfungi:YER020W	intact:EBI-2622179|uniprotkb:Q7Z4J7|uniprotkb:B2RD64|uniprotkb:Q9BUR1|uniprotkb:Q15838|intact:EBI-28978015|ensembl:ENSP00000385211|ensembl:ENSP00000385923	psi-mi:gpa2_yeast(display_long)|uniprotkb:YER020W(locus name)|uniprotkb:GPA2(gene name)|psi-mi:GPA2(display_short)|uniprotkb:SSP101(gene name synonym)|uniprotkb:GP2-alpha(gene name synonym)	psi-mi:nucb1_human(display_long)|uniprotkb:NUC(gene name synonym)|uniprotkb:CALNUC(gene name synonym)|uniprotkb:NUCB1(gene name)|psi-mi:NUCB1(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550684|imex:IM-24995-3242	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000000822|refseq:NP_010937.3|mint:P10823|dip:DIP-4346N|ensemblfungi:YER020W(gene)|ensemblfungi:YER020W_mRNA(transcript)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0007165"(signal transduction)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0008361"(regulation of cell size)|go:"GO:0009757"(hexose mediated signaling)|go:"GO:0010255"(glucose mediated signaling pathway)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0030437"(ascospore formation)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR002975(Fungal G-protein, alpha subunit)|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|reactome:R-SCE-112043|reactome:R-SCE-202040|reactome:R-SCE-399997|reactome:R-SCE-416476|reactome:R-SCE-416482|reactome:R-SCE-418592|reactome:R-SCE-434316|reactome:R-SCE-9013148	ensembl:ENSP00000385923|ensembl:ENSP00000385211|refseq:NP_006175.2|refseq:XP_016882334.1|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072718"(response to cisplatin)|go:"GO:0090498"(extrinsic component of Golgi membrane)|go:"GO:0098547"(lumenal side of Golgi membrane)|go:"GO:1903533"(regulation of protein targeting)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR040250|interpro:IPR040253|mint:Q02818|rcsb pdb:1SNL|reactome:R-HSA-381426|reactome:R-HSA-8957275|ensembl:ENSG00000104805(gene)|ensembl:ENST00000405315(transcript)|ensembl:ENST00000407032(transcript)|go:"GO:0001965"(G-protein alpha-subunit binding)|go:"GO:0003677"(DNA binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005769"(early endosome)	-	crc64:881B91792AE91748	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:ujQYVD/yCqR8/T2eRPygiuTD7Jg559292	rogid:exoVYPq5+NxEpgkm/gAQay/Uwuk9606	intact-crc:2AD3538B0A7FF3EF|rigid:KhM6hQ81nDdyd4SpwilDV4QHX/A	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O00444	uniprotkb:Q02793	intact:EBI-746202|uniprotkb:Q8IYF0|uniprotkb:Q96Q95|uniprotkb:B2RAL0|uniprotkb:B7Z837|uniprotkb:B7Z8G7|uniprotkb:Q9UD84|uniprotkb:Q9UDE2|ensembl:ENSP00000270861	intact:EBI-17260|uniprotkb:D6VTU2|ensemblfungi:YGL213C	psi-mi:plk4_human(display_long)|uniprotkb:Polo-like kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase Sak(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 18(gene name synonym)|uniprotkb:PLK4(gene name)|psi-mi:PLK4(display_short)|uniprotkb:SAK(gene name synonym)|uniprotkb:STK18(gene name synonym)	psi-mi:ski8_yeast(display_long)|uniprotkb:YGL213C(locus name)|uniprotkb:SKI8(gene name)|psi-mi:SKI8(display_short)|uniprotkb:REC103(gene name synonym)|uniprotkb:Superkiller protein 8(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550680|imex:IM-24995-3241	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001177728.1|refseq:NP_001177730.1|refseq:NP_055079.3|dip:DIP-34467N|rcsb pdb:5LHZ|rcsb pdb:6N45|rcsb pdb:6N46|rcsb pdb:6W38|rcsb pdb:6W3I|rcsb pdb:6W3J|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|rcsb pdb:5LHY|reactome:R-HSA-5620912|reactome:R-HSA-8854518|ensembl:ENSG00000142731(gene)|ensembl:ENST00000270861(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0001741"(XY body)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007099"(centriole replication)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0046601"(positive regulation of centriole replication)|go:"GO:0060271"(cilium assembly)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0098535"(de novo centriole assembly involved in multi-ciliated epithelial cell differentiation)|go:"GO:0098536"(deuterosome)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033696|interpro:IPR033698|interpro:IPR033699|interpro:IPR033700|mint:O00444|rcsb pdb:2N19|rcsb pdb:3COK|rcsb pdb:4JXF|rcsb pdb:4N7V|rcsb pdb:4N7Z|rcsb pdb:4N9J|rcsb pdb:4YUR|rcsb pdb:4YYP	refseq:NP_011302.1|sgd:S000003181|ensemblfungi:YGL213C(gene)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034622"|go:"GO:0051607"(defense response to virus)|go:"GO:0055087"(Ski complex)|go:"GO:0065004"(protein-DNA complex assembly)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|rcsb pdb:1S4U|rcsb pdb:1SQ9|rcsb pdb:4BUJ|rcsb pdb:5MC6|reactome:R-SCE-429958|reactome:R-SCE-674695|reactome:R-SCE-75955|ensemblfungi:YGL213C_mRNA(transcript)|dip:DIP-1653N|mint:Q02793	-	-	crc64:C5E7B9D2268F9727	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:xqjVEnoGXDk/+2AzLRAkyPK80OI9606	rogid:6K6FJYcctdlT1321Nv6pOnQPwq8559292	intact-crc:E3F1D20287341D3D|rigid:b94IcmKAtMw/tw+81P5wYoO+MTk	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P55347	uniprotkb:Q02642	intact:EBI-1373569|uniprotkb:O00528|uniprotkb:Q8IWT7|ensembl:ENSP00000291547	intact:EBI-6371|uniprotkb:Q02107|uniprotkb:D6W3X7|ensemblfungi:YPL037C	psi-mi:pknx1_human(display_long)|uniprotkb:PBX/knotted homeobox 1(gene name synonym)|uniprotkb:Homeobox protein PREP-1(gene name synonym)|uniprotkb:PKNOX1(gene name)|psi-mi:PKNOX1(display_short)|uniprotkb:PREP1(gene name synonym)	psi-mi:nacb1_yeast(display_long)|uniprotkb:EGD1(gene name)|psi-mi:EGD1(display_short)|uniprotkb:Beta-1-NAC(gene name synonym)|uniprotkb:GAL4 DNA-binding enhancer protein 1(gene name synonym)|uniprotkb:BTF3 homolog EGD1(gene name synonym)|uniprotkb:YPL037C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550664|imex:IM-24995-3237	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004562.2|ensembl:ENSG00000160199(gene)|ensembl:ENST00000291547(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0030217"(T cell differentiation)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0043010"(camera-type eye development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR008422(Coprinus cinereus mating-type protein)|interpro:IPR009057(Homeodomain-like)|interpro:IPR032453|rcsb pdb:1X2N|reactome:R-HSA-5617472	refseq:NP_015288.1|sgd:S000005958|mint:Q02642|dip:DIP-6561N|ensemblfungi:YPL037C(gene)|ensemblfungi:YPL037C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005854"(nascent polypeptide-associated complex)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR002715(Nascent polypeptide-associated complex NAC)|interpro:IPR038187|interpro:IPR039370	-	-	crc64:7C278A3DC79BF95B	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Lg1nUBFHfBFWvGVk9elIXobm5BA9606	rogid:Lrun0emRynb8tO3ViEF/fkUI9SQ559292	intact-crc:88DDC45E42691E81|rigid:bfalhloM1t44nFIvMTfX3o8/9XE	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O96015	uniprotkb:Q02647	intact:EBI-742362|uniprotkb:Q6FGB2|uniprotkb:Q6FGD0|ensembl:ENSP00000216068	intact:EBI-6240|uniprotkb:D6VT54|ensemblfungi:YDR424C	psi-mi:dnal4_human(display_long)|uniprotkb:DNAL4(gene name)|psi-mi:DNAL4(display_short)	psi-mi:dyl1_yeast(display_long)|uniprotkb:DYN2(gene name)|psi-mi:DYN2(display_short)|uniprotkb:SLC1(gene name synonym)|uniprotkb:YDR424C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550672|imex:IM-24995-3239	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005731.1|ensembl:ENSG00000100246(gene)|ensembl:ENST00000216068(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0030286"(dynein complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0051959"(dynein light intermediate chain binding)|go:"GO:2000582"(obsolete positive regulation of microtubule motor activity, plus-end-directed)|interpro:IPR001372(Dynein light chain, type 1 and 2)|interpro:IPR037177|mint:O96015|reactome:R-HSA-177504|go:"GO:0003777"(microtubule motor activity)	refseq:NP_010712.1|sgd:S000002832|dip:DIP-6480N|mint:Q02647|interpro:IPR001372(Dynein light chain, type 1 and 2)|interpro:IPR019763|interpro:IPR037177|rcsb pdb:4DS1|rcsb pdb:4HT6|reactome:R-SCE-6798695|ensemblfungi:YDR424C(gene)|ensemblfungi:YDR424C_mRNA(transcript)|go:"GO:0005643"(nuclear pore)|go:"GO:0005868"(cytoplasmic dynein complex)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0015031"(protein transport)|go:"GO:0030286"(dynein complex)|go:"GO:0030473"(nuclear migration along microtubule)|go:"GO:0034399"(nuclear periphery)|go:"GO:0040001"(establishment of mitotic spindle localization)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0051028"(mRNA transport)|go:"GO:0051292"(nuclear pore complex assembly)|go:"GO:0051959"(dynein light intermediate chain binding)|go:"GO:1990429"(peroxisomal importomer complex)|go:"GO:2000582"(obsolete positive regulation of microtubule motor activity, plus-end-directed)	-	-	crc64:C25A690F35C3CEEC	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:VT8OXlxBh2Jy6Bb4vMkrAY9M6AA9606	rogid:VzzUwItKMyp/zI7n/iI7VK4QiEA559292	intact-crc:ED17C2DF7C6E2400|rigid:eccgkpyu1hz19GLGuUcA3KLr8xU	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q02642	uniprotkb:P50222	intact:EBI-6371|uniprotkb:Q02107|uniprotkb:D6W3X7|ensemblfungi:YPL037C	intact:EBI-748397|uniprotkb:O75263|ensembl:ENSP00000262041|uniprotkb:Q9UPL6|uniprotkb:B2R8I7|intact:EBI-10172134|intact:EBI-11522964|intact:EBI-11750003|intact:EBI-12702266|uniprotkb:A4D127	psi-mi:nacb1_yeast(display_long)|uniprotkb:EGD1(gene name)|psi-mi:EGD1(display_short)|uniprotkb:Beta-1-NAC(gene name synonym)|uniprotkb:GAL4 DNA-binding enhancer protein 1(gene name synonym)|uniprotkb:BTF3 homolog EGD1(gene name synonym)|uniprotkb:YPL037C(locus name)	psi-mi:meox2_human(display_long)|uniprotkb:Mesenchyme homeobox 2(gene name synonym)|uniprotkb:Growth arrest-specific homeobox(gene name synonym)|uniprotkb:MEOX2(gene name)|psi-mi:MEOX2(display_short)|uniprotkb:GAX(gene name synonym)|uniprotkb:MOX2(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550668|imex:IM-24995-3238	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015288.1|sgd:S000005958|mint:Q02642|dip:DIP-6561N|ensemblfungi:YPL037C(gene)|ensemblfungi:YPL037C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005854"(nascent polypeptide-associated complex)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR002715(Nascent polypeptide-associated complex NAC)|interpro:IPR038187|interpro:IPR039370	ensembl:ENSG00000106511(gene)|ensembl:ENST00000262041(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0001757"(somite specification)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007275"(multicellular organism development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008015"(blood circulation)|go:"GO:0016607"(nuclear speck)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060173"(limb development)|go:"GO:0061053"(somite development)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR042634|refseq:NP_005915.2	-	crc64:7C278A3DC79BF95B	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2017/05/26	rogid:Lrun0emRynb8tO3ViEF/fkUI9SQ559292	rogid:fMv0ruKikzQ3MC0PBvJ3pOAjW+U9606	intact-crc:02A8E5E2DEC6153E|rigid:n/w0hlOZmoo3PjnN4OQurGwqP9o	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q02793	uniprotkb:P38432	intact:EBI-17260|uniprotkb:D6VTU2|ensemblfungi:YGL213C	intact:EBI-945751|uniprotkb:B2R931|ensembl:ENSP00000240316	psi-mi:ski8_yeast(display_long)|uniprotkb:YGL213C(locus name)|uniprotkb:SKI8(gene name)|psi-mi:SKI8(display_short)|uniprotkb:REC103(gene name synonym)|uniprotkb:Superkiller protein 8(gene name synonym)	psi-mi:coil_human(display_long)|uniprotkb:COIL(gene name)|psi-mi:COIL(display_short)|uniprotkb:CLN80(gene name synonym)|uniprotkb:p80-coilin(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550676|imex:IM-24995-3240	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011302.1|sgd:S000003181|ensemblfungi:YGL213C(gene)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034622"|go:"GO:0051607"(defense response to virus)|go:"GO:0055087"(Ski complex)|go:"GO:0065004"(protein-DNA complex assembly)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|rcsb pdb:1S4U|rcsb pdb:1SQ9|rcsb pdb:4BUJ|rcsb pdb:5MC6|reactome:R-SCE-429958|reactome:R-SCE-674695|reactome:R-SCE-75955|ensemblfungi:YGL213C_mRNA(transcript)|dip:DIP-1653N|mint:Q02793	refseq:NP_004636.1|dip:DIP-38503N|ensembl:ENSG00000121058(gene)|ensembl:ENST00000240316(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0015030"(Cajal body)|go:"GO:0016020"(membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0030619"(U1 snRNA binding)|go:"GO:0030620"(U2 snRNA binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR024822|interpro:IPR031722|mint:P38432	-	crc64:C5E7B9D2268F9727	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:6K6FJYcctdlT1321Nv6pOnQPwq8559292	rogid:hd5p6AbyA/GYNEeca99Mdb41qM09606	intact-crc:23C9C2DEB86C8EED|rigid:ABp9irOa3eI3gW27e08nrIbXS78	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q02821	uniprotkb:O00635	intact:EBI-1797|uniprotkb:D6W0Z8|ensemblfungi:YNL189W	intact:EBI-2130415|uniprotkb:B2R862|ensembl:ENSP00000349596	psi-mi:ima1_yeast(display_long)|uniprotkb:SRP1(gene name)|psi-mi:SRP1(display_short)|uniprotkb:KAP60(gene name synonym)|uniprotkb:YNL189W(locus name)|uniprotkb:N1606(orf name)|uniprotkb:Karyopherin subunit alpha(gene name synonym)|uniprotkb:Karyopherin-60(gene name synonym)|uniprotkb:Serine-rich RNA polymerase I suppressor protein(gene name synonym)	psi-mi:tri38_human(display_long)|uniprotkb:TRIM38(gene name)|psi-mi:TRIM38(display_short)|uniprotkb:RNF15(gene name synonym)|uniprotkb:RORET(gene name synonym)|uniprotkb:RING finger protein 15(gene name synonym)|uniprotkb:Zinc finger protein RoRet(gene name synonym)|uniprotkb:Tripartite motif-containing protein 38(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM38(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550716|imex:IM-24995-3250	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014210.1|sgd:S000005133|dip:DIP-728N|mint:Q02821|ensemblfungi:YNL189W(gene)|ensemblfungi:YNL189W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0031144"(proteasome localization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042564"(NLS-dependent protein nuclear import complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|rcsb pdb:1BK5|rcsb pdb:1BK6|rcsb pdb:1EE4|rcsb pdb:1EE5|rcsb pdb:1UN0|rcsb pdb:1WA5|rcsb pdb:2C1T|rcsb pdb:4PVZ|rcsb pdb:4XZR|rcsb pdb:5H2W|rcsb pdb:5H2X|rcsb pdb:5T94	refseq:NP_006346.1|refseq:XP_005248856.1|refseq:XP_005248857.1|ensembl:ENSG00000112343(gene)|ensembl:ENST00000357085(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046598"(positive regulation of viral entry into host cell)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR035790|interpro:IPR043136|reactome:R-HSA-877300	-	crc64:8D3A0CB76F2E7C00	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:NyzC93xnBCb8DX/AH346lwg4u2A559292	rogid:Zh4X/6v/qKZlDkMV6hhn7OsvPnQ9606	intact-crc:09AE236EEA146A07|rigid:oSEeJqNHyIdmz0zFygbv5rM4TXg	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P35520	uniprotkb:Q02821	intact:EBI-740135|uniprotkb:Q99425|uniprotkb:Q9BWC5|uniprotkb:B2R993|uniprotkb:D3DSK4|intact:EBI-14245939|ensembl:ENSP00000344460|ensembl:ENSP00000352643|ensembl:ENSP00000381225|ensembl:ENSP00000381231	intact:EBI-1797|uniprotkb:D6W0Z8|ensemblfungi:YNL189W	psi-mi:cbs_human(display_long)|uniprotkb:CBS(gene name)|psi-mi:CBS(display_short)|uniprotkb:Serine sulfhydrase(gene name synonym)|uniprotkb:Beta-thionase(gene name synonym)	psi-mi:ima1_yeast(display_long)|uniprotkb:SRP1(gene name)|psi-mi:SRP1(display_short)|uniprotkb:KAP60(gene name synonym)|uniprotkb:YNL189W(locus name)|uniprotkb:N1606(orf name)|uniprotkb:Karyopherin subunit alpha(gene name synonym)|uniprotkb:Karyopherin-60(gene name synonym)|uniprotkb:Serine-rich RNA polymerase I suppressor protein(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550712|imex:IM-24995-3249	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000062.1|refseq:NP_001171479.1|refseq:NP_001171480.1|ensembl:ENSG00000160200(gene)|ensembl:ENST00000352178(transcript)|ensembl:ENST00000359624(transcript)|ensembl:ENST00000398158(transcript)|go:"GO:0004122"(cystathionine beta-synthase activity)|ensembl:ENST00000398165(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006535"(cysteine biosynthetic process from serine)|go:"GO:0006563"(L-serine metabolic process)|go:"GO:0006565"(L-serine catabolic process)|go:"GO:0019343"(cysteine biosynthetic process via cystathionine)|go:"GO:0019344"(cysteine biosynthetic process)|go:"GO:0019346"(transsulfuration)|go:"GO:0019448"(L-cysteine catabolic process)|go:"GO:0019825"(oxygen binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0020037"(heme binding)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042262"(DNA protection)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043418"(homocysteine catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0050421"("nitrite reductase (NO-forming) activity")|go:"GO:0050667"(homocysteine metabolic process)|go:"GO:0070025"(carbon monoxide binding)|go:"GO:0070026"(nitric oxide binding)|go:"GO:0070814"(hydrogen sulfide biosynthetic process)|go:"GO:0072341"(modified amino acid binding)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR001216(Cysteine synthase/cystathionine beta-synthase P-phosphate-binding site)|interpro:IPR001926(Pyridoxal phosphate-dependent enzyme, beta subunit)|interpro:IPR005857(Cystathionine beta-synthase)|interpro:IPR036052|mint:P35520|rcsb pdb:1JBQ|rcsb pdb:1M54|rcsb pdb:4COO|rcsb pdb:4L0D|rcsb pdb:4L27|rcsb pdb:4L28|rcsb pdb:4L3V|rcsb pdb:4PCU|rcsb pdb:4UUU|rcsb pdb:5MMS|reactome:R-HSA-1614603|reactome:R-HSA-2408508|refseq:XP_011528079.1|refseq:XP_011528083.1|refseq:XP_011528084.1|refseq:XP_011544396.1|refseq:XP_011544397.1|refseq:XP_011544399.1|refseq:XP_011544400.1|refseq:XP_011544401.1|refseq:NP_001307227.1|refseq:NP_001308002.1|refseq:XP_016883700.1|refseq:XP_016883701.1|refseq:XP_016883702.1|refseq:XP_016883703.1|refseq:XP_016883704.1|refseq:XP_016883705.1|refseq:XP_016883706.1|refseq:XP_016883707.1|refseq:XP_016883978.1|refseq:XP_016883979.1|refseq:XP_016883980.1|refseq:XP_016883981.1	refseq:NP_014210.1|sgd:S000005133|dip:DIP-728N|mint:Q02821|ensemblfungi:YNL189W(gene)|ensemblfungi:YNL189W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0031144"(proteasome localization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042564"(NLS-dependent protein nuclear import complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|rcsb pdb:1BK5|rcsb pdb:1BK6|rcsb pdb:1EE4|rcsb pdb:1EE5|rcsb pdb:1UN0|rcsb pdb:1WA5|rcsb pdb:2C1T|rcsb pdb:4PVZ|rcsb pdb:4XZR|rcsb pdb:5H2W|rcsb pdb:5H2X|rcsb pdb:5T94	-	-	crc64:8D3A0CB76F2E7C00	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:f9eo0cPOHppVY7Nqejag3YyK18s9606	rogid:NyzC93xnBCb8DX/AH346lwg4u2A559292	intact-crc:2B1E71B60EC832D4|rigid:sHjkU2Xr5Rp+0zmlZ6aoAynaMus	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q02821	uniprotkb:P63261	intact:EBI-1797|uniprotkb:D6W0Z8|ensemblfungi:YNL189W	intact:EBI-351292|uniprotkb:P02571|uniprotkb:P14104|uniprotkb:P99022|uniprotkb:Q5U032|uniprotkb:Q96E67|uniprotkb:A8K7C2|ensembl:ENSP00000505060|ensembl:ENSP00000505193|ensembl:ENSP00000505235|ensembl:ENSP00000506126|ensembl:ENSP00000506201|ensembl:ENSP00000506253|ensembl:ENSP00000458162|ensembl:ENSP00000458435|ensembl:ENSP00000459119|ensembl:ENSP00000459124|ensembl:ENSP00000460464|ensembl:ENSP00000460660|ensembl:ENSP00000461672|ensembl:ENSP00000466346|ensembl:ENSP00000477968	psi-mi:ima1_yeast(display_long)|uniprotkb:SRP1(gene name)|psi-mi:SRP1(display_short)|uniprotkb:KAP60(gene name synonym)|uniprotkb:YNL189W(locus name)|uniprotkb:N1606(orf name)|uniprotkb:Karyopherin subunit alpha(gene name synonym)|uniprotkb:Karyopherin-60(gene name synonym)|uniprotkb:Serine-rich RNA polymerase I suppressor protein(gene name synonym)	psi-mi:actg_human(display_long)|uniprotkb:ACTG1(gene name)|psi-mi:ACTG1(display_short)|uniprotkb:ACTG(gene name synonym)|uniprotkb:Gamma-actin(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550708|imex:IM-24995-3248	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014210.1|sgd:S000005133|dip:DIP-728N|mint:Q02821|ensemblfungi:YNL189W(gene)|ensemblfungi:YNL189W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0031144"(proteasome localization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042564"(NLS-dependent protein nuclear import complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|rcsb pdb:1BK5|rcsb pdb:1BK6|rcsb pdb:1EE4|rcsb pdb:1EE5|rcsb pdb:1UN0|rcsb pdb:1WA5|rcsb pdb:2C1T|rcsb pdb:4PVZ|rcsb pdb:4XZR|rcsb pdb:5H2W|rcsb pdb:5H2X|rcsb pdb:5T94	refseq:NP_001186883.1|refseq:NP_001605.1|ensembl:ENST00000570382(transcript)|ensembl:ENSG00000184009(gene)|ensembl:ENST00000571721(transcript)|ensembl:ENST00000573283(transcript)|ensembl:ENST00000575087(transcript)|ensembl:ENST00000575659(transcript)|ensembl:ENST00000575842(transcript)|ensembl:ENST00000575994(transcript)|ensembl:ENST00000576544(transcript)|ensembl:ENST00000615544(transcript)|ensembl:ENST00000679480(transcript)|ensembl:ENST00000679778(transcript)|ensembl:ENST00000680227(transcript)|ensembl:ENST00000680727(transcript)|ensembl:ENST00000681052(transcript)|ensembl:ENST00000681842(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0001895"(retina homeostasis)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005522"(profilin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0030016"(myofibril)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031941"(filamentous actin)|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0044305"(calyx of Held)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0051492"(regulation of stress fiber assembly)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070527"(platelet aggregation)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0072562"(blood microparticle)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0097433"(dense body)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098973"(structural constituent of postsynaptic actin cytoskeleton)|go:"GO:0120192"(tight junction assembly)|go:"GO:0120220"(basal body patch)|go:"GO:0150111"(regulation of transepithelial transport)|go:"GO:1902396"(protein localization to bicellular tight junction)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P63261|rcsb pdb:5JLH|rcsb pdb:6CXI|rcsb pdb:6CXJ|rcsb pdb:6G2T|rcsb pdb:6V62|rcsb pdb:6V63|rcsb pdb:6WK1|rcsb pdb:6WK2|reactome:R-HSA-1445148|reactome:R-HSA-190873|reactome:R-HSA-196025|reactome:R-HSA-2029482|reactome:R-HSA-3928662|reactome:R-HSA-3928665|reactome:R-HSA-418990|reactome:R-HSA-437239|reactome:R-HSA-4420097|reactome:R-HSA-445095|reactome:R-HSA-446353|reactome:R-HSA-5626467|reactome:R-HSA-5663213|reactome:R-HSA-5663220|reactome:R-HSA-5674135|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8856828|reactome:R-HSA-9013418|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9662360|reactome:R-HSA-9662361|reactome:R-HSA-9664422	-	crc64:8D3A0CB76F2E7C00	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:NyzC93xnBCb8DX/AH346lwg4u2A559292	rogid:B2OOsE06lTfo90H3g8tlmUJQ7cY9606	intact-crc:35EDB99DBCBC81E1|rigid:eAmSecUW+kV9D40b0fX57lQh+ZU	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:A0A0C4DGF1	uniprotkb:Q02821	intact:EBI-10188476|ensembl:ENSP00000433657	intact:EBI-1797|uniprotkb:D6W0Z8|ensemblfungi:YNL189W	psi-mi:a0a0c4dgf1_human(display_long)|uniprotkb:ZBTB32(gene name)|psi-mi:ZBTB32(display_short)	psi-mi:ima1_yeast(display_long)|uniprotkb:SRP1(gene name)|psi-mi:SRP1(display_short)|uniprotkb:KAP60(gene name synonym)|uniprotkb:YNL189W(locus name)|uniprotkb:N1606(orf name)|uniprotkb:Karyopherin subunit alpha(gene name synonym)|uniprotkb:Karyopherin-60(gene name synonym)|uniprotkb:Serine-rich RNA polymerase I suppressor protein(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550692|imex:IM-24995-3244	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|ensembl:ENSG00000011590(gene)|ensembl:ENST00000481182(transcript)|go:"GO:0042802"(identical protein binding)	refseq:NP_014210.1|sgd:S000005133|dip:DIP-728N|mint:Q02821|ensemblfungi:YNL189W(gene)|ensemblfungi:YNL189W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0031144"(proteasome localization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042564"(NLS-dependent protein nuclear import complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|rcsb pdb:1BK5|rcsb pdb:1BK6|rcsb pdb:1EE4|rcsb pdb:1EE5|rcsb pdb:1UN0|rcsb pdb:1WA5|rcsb pdb:2C1T|rcsb pdb:4PVZ|rcsb pdb:4XZR|rcsb pdb:5H2W|rcsb pdb:5H2X|rcsb pdb:5T94	-	-	crc64:8D3A0CB76F2E7C00	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:w3k7YT4kw/T+Xi5YBqGHSpHtwMM9606	rogid:NyzC93xnBCb8DX/AH346lwg4u2A559292	intact-crc:9BA661D9B5002275|rigid:SJnLFil/JKxND/k7uaUdrRDCNwE	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q02821	uniprotkb:Q7Z6G3-2	intact:EBI-1797|uniprotkb:D6W0Z8|ensemblfungi:YNL189W	intact:EBI-10172876|ensembl:ENSP00000457354|intact:EBI-14062040	psi-mi:ima1_yeast(display_long)|uniprotkb:SRP1(gene name)|psi-mi:SRP1(display_short)|uniprotkb:KAP60(gene name synonym)|uniprotkb:YNL189W(locus name)|uniprotkb:N1606(orf name)|uniprotkb:Karyopherin subunit alpha(gene name synonym)|uniprotkb:Karyopherin-60(gene name synonym)|uniprotkb:Serine-rich RNA polymerase I suppressor protein(gene name synonym)	psi-mi:q7z6g3-2(display_long)|uniprotkb:EFCBP2(gene name synonym)|uniprotkb:Neuronal calcium-binding protein 2(gene name synonym)|uniprotkb:Synaptotagmin-interacting protein 2(gene name synonym)|uniprotkb:NECAB2(gene name)|psi-mi:NECAB2(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550700|imex:IM-24995-3246	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014210.1|sgd:S000005133|dip:DIP-728N|mint:Q02821|ensemblfungi:YNL189W(gene)|ensemblfungi:YNL189W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0031144"(proteasome localization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042564"(NLS-dependent protein nuclear import complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|rcsb pdb:1BK5|rcsb pdb:1BK6|rcsb pdb:1EE4|rcsb pdb:1EE5|rcsb pdb:1UN0|rcsb pdb:1WA5|rcsb pdb:2C1T|rcsb pdb:4PVZ|rcsb pdb:4XZR|rcsb pdb:5H2W|rcsb pdb:5H2X|rcsb pdb:5T94	ensembl:ENSG00000103154(gene)|ensembl:ENST00000565691(transcript)|uniprotkb:Q7Z6G3-2(isoform-parent)|intact:EBI-950070(isoform-parent)	-	crc64:8D3A0CB76F2E7C00	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:NyzC93xnBCb8DX/AH346lwg4u2A559292	rogid:4S7oIx6h+mKzV3EPxqcfMNqaNko9606	intact-crc:EAA6DB422D51D6FD|rigid:hrdlqQvsmzhYRpTN4bYczcX5pEA	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q02821	uniprotkb:Q96A10	intact:EBI-1797|uniprotkb:D6W0Z8|ensemblfungi:YNL189W	intact:EBI-10486892|intact:EBI-11528237|ensembl:ENSP00000488921	psi-mi:ima1_yeast(display_long)|uniprotkb:SRP1(gene name)|psi-mi:SRP1(display_short)|uniprotkb:KAP60(gene name synonym)|uniprotkb:YNL189W(locus name)|uniprotkb:N1606(orf name)|uniprotkb:Karyopherin subunit alpha(gene name synonym)|uniprotkb:Karyopherin-60(gene name synonym)|uniprotkb:Serine-rich RNA polymerase I suppressor protein(gene name synonym)	psi-mi:q96a10_human(display_long)|uniprotkb:ERVK3-1(gene name)|psi-mi:ERVK3-1(display_short)|uniprotkb:hCG_2043597(orf name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550696|imex:IM-24995-3245	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014210.1|sgd:S000005133|dip:DIP-728N|mint:Q02821|ensemblfungi:YNL189W(gene)|ensemblfungi:YNL189W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0031144"(proteasome localization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042564"(NLS-dependent protein nuclear import complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|rcsb pdb:1BK5|rcsb pdb:1BK6|rcsb pdb:1EE4|rcsb pdb:1EE5|rcsb pdb:1UN0|rcsb pdb:1WA5|rcsb pdb:2C1T|rcsb pdb:4PVZ|rcsb pdb:4XZR|rcsb pdb:5H2W|rcsb pdb:5H2X|rcsb pdb:5T94	ensembl:ENSG00000142396(gene)|ensembl:ENST00000427361(transcript)	-	crc64:8D3A0CB76F2E7C00	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/17	rogid:NyzC93xnBCb8DX/AH346lwg4u2A559292	rogid:UGl9ZpnDNz58eECRstJXxM5bj9I9606	intact-crc:12095C3B8BF7FD28|rigid:PfXqrP00JKkZ9DrWN17KbMlKCFg	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q02821	uniprotkb:P20591	intact:EBI-1797|uniprotkb:D6W0Z8|ensemblfungi:YNL189W	intact:EBI-929476|uniprotkb:D3DSI8|uniprotkb:B2RDA5|uniprotkb:B3KU10|uniprotkb:C9IYV7|uniprotkb:C9J8D6|uniprotkb:C9JN19|uniprotkb:C9JN88|uniprotkb:C9JUL1|uniprotkb:C9JZS6|uniprotkb:Q86YP5|uniprotkb:Q96CI3|ensembl:ENSP00000381599|ensembl:ENSP00000381601|ensembl:ENSP00000392151|ensembl:ENSP00000402215|ensembl:ENSP00000408498|ensembl:ENSP00000410523|ensembl:ENSP00000505029|ensembl:ENSP00000505047|ensembl:ENSP00000505051|ensembl:ENSP00000505189|ensembl:ENSP00000505457|ensembl:ENSP00000505489|ensembl:ENSP00000505630|ensembl:ENSP00000505657|ensembl:ENSP00000505669|ensembl:ENSP00000505781|ensembl:ENSP00000505874|ensembl:ENSP00000506047|ensembl:ENSP00000506062|ensembl:ENSP00000506183|ensembl:ENSP00000506199|ensembl:ENSP00000506220|ensembl:ENSP00000506270|ensembl:ENSP00000506348|ensembl:ENSP00000506372|ensembl:ENSP00000506395|ensembl:ENSP00000506481|ensembl:ENSP00000506512|ensembl:ENSP00000506690|ensembl:ENSP00000506712	psi-mi:ima1_yeast(display_long)|uniprotkb:SRP1(gene name)|psi-mi:SRP1(display_short)|uniprotkb:KAP60(gene name synonym)|uniprotkb:YNL189W(locus name)|uniprotkb:N1606(orf name)|uniprotkb:Karyopherin subunit alpha(gene name synonym)|uniprotkb:Karyopherin-60(gene name synonym)|uniprotkb:Serine-rich RNA polymerase I suppressor protein(gene name synonym)	psi-mi:mx1_human(display_long)|uniprotkb:MX1(gene name)|psi-mi:MX1(display_short)|uniprotkb:Myxovirus resistance protein 1(gene name synonym)|uniprotkb:Interferon-regulated resistance GTP-binding protein MxA(gene name synonym)|uniprotkb:Interferon-induced protein p78(gene name synonym)|uniprotkb:Myxoma resistance protein 1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550704|imex:IM-24995-3247	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014210.1|sgd:S000005133|dip:DIP-728N|mint:Q02821|ensemblfungi:YNL189W(gene)|ensemblfungi:YNL189W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0031144"(proteasome localization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042564"(NLS-dependent protein nuclear import complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|rcsb pdb:1BK5|rcsb pdb:1BK6|rcsb pdb:1EE4|rcsb pdb:1EE5|rcsb pdb:1UN0|rcsb pdb:1WA5|rcsb pdb:2C1T|rcsb pdb:4PVZ|rcsb pdb:4XZR|rcsb pdb:5H2W|rcsb pdb:5H2X|rcsb pdb:5T94	refseq:NP_001269849.1|refseq:NP_001138397.1|refseq:NP_001171517.1|refseq:NP_002453.2|refseq:XP_011527870.1|refseq:XP_005261037.1|refseq:XP_005261038.1|refseq:XP_005261039.1|refseq:XP_005261035.1|refseq:XP_005261036.1|refseq:XP_016883838.1|refseq:XP_016883839.1|dip:DIP-35694N|ensembl:ENSG00000157601(gene)|ensembl:ENST00000398598(transcript)|ensembl:ENST00000398600(transcript)|ensembl:ENST00000413778(transcript)|ensembl:ENST00000417963(transcript)|ensembl:ENST00000419044(transcript)|ensembl:ENST00000455164(transcript)|ensembl:ENST00000679445(transcript)|ensembl:ENST00000679464(transcript)|ensembl:ENST00000679543(transcript)|ensembl:ENST00000679626(transcript)|ensembl:ENST00000679705(transcript)|ensembl:ENST00000679911(transcript)|ensembl:ENST00000680176(transcript)|ensembl:ENST00000680182(transcript)|ensembl:ENST00000680347(transcript)|ensembl:ENST00000680364(transcript)|ensembl:ENST00000680536(transcript)|ensembl:ENST00000680629(transcript)|ensembl:ENST00000680760(transcript)|ensembl:ENST00000680776(transcript)|ensembl:ENST00000681039(transcript)|ensembl:ENST00000681191(transcript)|ensembl:ENST00000681266(transcript)|ensembl:ENST00000681415(transcript)|ensembl:ENST00000681607(transcript)|ensembl:ENST00000681671(transcript)|ensembl:ENST00000681849(transcript)|ensembl:ENST00000681857(transcript)|ensembl:ENST00000681867(transcript)|ensembl:ENST00000681896(transcript)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0003374"(dynamin family protein polymerization involved in mitochondrial fission)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0006952"(defense response)|go:"GO:0007165"(signal transduction)|go:"GO:0008017"(microtubule binding)|go:"GO:0009615"(response to virus)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016185"(synaptic vesicle budding from presynaptic endocytic zone membrane)|go:"GO:0030424"(axon)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031623"(receptor internalization)|go:"GO:0031965"(nuclear membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0034340"(response to type I interferon)|go:"GO:0042802"(identical protein binding)|go:"GO:0044327"(dendritic spine head)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0051607"(defense response to virus)|go:"GO:0061025"(membrane fusion)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:0098793"(presynapse)|go:"GO:0098844"(postsynaptic endocytic zone membrane)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:0140374"(antiviral innate immune response)|interpro:IPR000375(Dynamin central region)|interpro:IPR001401(Dynamin, GTPase region)|interpro:IPR003130(Dynamin GTPase effector)|interpro:IPR019762|interpro:IPR020850|interpro:IPR022812|interpro:IPR027417|interpro:IPR030381|mint:P20591|rcsb pdb:3LJB|rcsb pdb:3SZR|rcsb pdb:3ZYS|rcsb pdb:4P4S|rcsb pdb:4P4T|rcsb pdb:4P4U|rcsb pdb:5GTM|reactome:R-HSA-1169408|reactome:R-HSA-909733	-	crc64:8D3A0CB76F2E7C00	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:NyzC93xnBCb8DX/AH346lwg4u2A559292	rogid:9rO7Zyl6v0Kq3xw6MKbVefk1hCA9606	intact-crc:6F40CFBEC64CD4B3|rigid:Ss/YtFxCh1OwLwdQC3gxslONYCc	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q02831	uniprotkb:P19012	intact:EBI-31828|uniprotkb:D6W3T9|ensemblfungi:YPL077C	intact:EBI-739566|uniprotkb:Q53XV8|uniprotkb:Q9BUG4|uniprotkb:B3KQY1|uniprotkb:B3KRA2|uniprotkb:E0CX14|ensembl:ENSP00000254043|ensembl:ENSP00000377546	psi-mi:yp077_yeast(display_long)|uniprotkb:YPL077C(locus name)	psi-mi:k1c15_human(display_long)|uniprotkb:KRT15(gene name)|psi-mi:KRT15(display_short)|uniprotkb:KRTB(gene name synonym)|uniprotkb:Cytokeratin-15(gene name synonym)|uniprotkb:Keratin-15(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550736|imex:IM-24995-3255	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005998|refseq:NP_015248.1|dip:DIP-4022N|ensemblfungi:YPL077C(gene)|ensemblfungi:YPL077C_mRNA(transcript)	refseq:NP_002266.2|ensembl:ENSG00000171346(gene)|ensembl:ENST00000254043(transcript)|ensembl:ENST00000393976(transcript)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0008544"(epidermis development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097110"(scaffold protein binding)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR039008|mint:P19012|reactome:R-HSA-6805567|reactome:R-HSA-6809371	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:yqOn4GWKNmFZ7UvGmyBEpgoyKlA559292	rogid:WrZQBYQvrWcfrR5ojWXrXp6spPE9606	intact-crc:9B693C139375C739|rigid:P9Ll3LXUd9uJ+1g3ix//cxWtTZM	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O95751	uniprotkb:Q02831	intact:EBI-740738|ensembl:ENSP00000359557|uniprotkb:Q6IAR6	intact:EBI-31828|uniprotkb:D6W3T9|ensemblfungi:YPL077C	psi-mi:ldoc1_human(display_long)|uniprotkb:Leucine zipper protein down-regulated in cancer cells(gene name synonym)|uniprotkb:LDOC1(gene name)|psi-mi:LDOC1(display_short)|uniprotkb:BCUR1(gene name synonym)	psi-mi:yp077_yeast(display_long)|uniprotkb:YPL077C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550732|imex:IM-24995-3254	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_036449.1|ensembl:ENSG00000182195(gene)|ensembl:ENST00000370526(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071225"(cellular response to muramyl dipeptide)|interpro:IPR032549|interpro:IPR032567	sgd:S000005998|refseq:NP_015248.1|dip:DIP-4022N|ensemblfungi:YPL077C(gene)|ensemblfungi:YPL077C_mRNA(transcript)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:Ediu0oNiZ/+YVY8l3fNdgP5A+v09606	rogid:yqOn4GWKNmFZ7UvGmyBEpgoyKlA559292	intact-crc:8F1E14BB36300966|rigid:fHBBJNu1VoIgDlWXQtH3kp28p4c	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P13196	uniprotkb:Q02821	intact:EBI-3905054|ensembl:ENSP00000309259|ensembl:ENSP00000378416|ensembl:ENSP00000417719|ensembl:ENSP00000418779	intact:EBI-1797|uniprotkb:D6W0Z8|ensemblfungi:YNL189W	psi-mi:hem1_human(display_long)|uniprotkb:ALAS1(gene name)|psi-mi:ALAS1(display_short)|uniprotkb:ALAS3(gene name synonym)|uniprotkb:ALASH(gene name synonym)|uniprotkb:5-aminolevulinic acid synthase 1(gene name synonym)|uniprotkb:Delta-ALA synthase 1(gene name synonym)|uniprotkb:Delta-aminolevulinate synthase 1(gene name synonym)|uniprotkb:OK/SW-cl.121(orf name)	psi-mi:ima1_yeast(display_long)|uniprotkb:SRP1(gene name)|psi-mi:SRP1(display_short)|uniprotkb:KAP60(gene name synonym)|uniprotkb:YNL189W(locus name)|uniprotkb:N1606(orf name)|uniprotkb:Karyopherin subunit alpha(gene name synonym)|uniprotkb:Karyopherin-60(gene name synonym)|uniprotkb:Serine-rich RNA polymerase I suppressor protein(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550720|imex:IM-24995-3251	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001291372.1|refseq:NP_001291373.1|refseq:NP_000679.1|refseq:NP_954635.1|go:"GO:0006783"(heme biosynthetic process)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0042541"(hemoglobin biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0048821"(erythrocyte development)|ensembl:ENSG00000023330(gene)|ensembl:ENST00000310271(transcript)|ensembl:ENST00000394965(transcript)|ensembl:ENST00000469224(transcript)|ensembl:ENST00000484952(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0003870"(5-aminolevulinate synthase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|interpro:IPR001917(Aminotransferase, class-II, pyridoxal-phosphate binding site)|interpro:IPR004839(Aminotransferase, class I and II)|interpro:IPR010961(Tetrapyrrole biosynthesis, 5-aminolevulinic acid synthase)|interpro:IPR015118(5-aminolevulinate synthase presequence)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|mint:P13196|reactome:R-HSA-189451|reactome:R-HSA-1989781|reactome:R-HSA-2151201|go:"GO:0006782"(protoporphyrinogen IX biosynthetic process)	refseq:NP_014210.1|sgd:S000005133|dip:DIP-728N|mint:Q02821|ensemblfungi:YNL189W(gene)|ensemblfungi:YNL189W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0031144"(proteasome localization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042564"(NLS-dependent protein nuclear import complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|rcsb pdb:1BK5|rcsb pdb:1BK6|rcsb pdb:1EE4|rcsb pdb:1EE5|rcsb pdb:1UN0|rcsb pdb:1WA5|rcsb pdb:2C1T|rcsb pdb:4PVZ|rcsb pdb:4XZR|rcsb pdb:5H2W|rcsb pdb:5H2X|rcsb pdb:5T94	-	-	crc64:8D3A0CB76F2E7C00	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:HFjJ6zrRF9UYD7LMB6A3CcxcS7c9606	rogid:NyzC93xnBCb8DX/AH346lwg4u2A559292	intact-crc:05C9280A3C28F6BD|rigid:I1igYh7FqhViL3owJKuaKs/NN4g	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q02821	uniprotkb:P60709	intact:EBI-1797|uniprotkb:D6W0Z8|ensemblfungi:YNL189W	intact:EBI-353944|uniprotkb:P02570|uniprotkb:P70514|uniprotkb:P99021|uniprotkb:Q11211|uniprotkb:Q64316|uniprotkb:Q75MN2|uniprotkb:Q96B34|uniprotkb:Q96HG5|ensembl:ENSP00000494269|ensembl:ENSP00000494750|ensembl:ENSP00000495995|ensembl:ENSP00000501862|ensembl:ENSP00000502821	psi-mi:ima1_yeast(display_long)|uniprotkb:SRP1(gene name)|psi-mi:SRP1(display_short)|uniprotkb:KAP60(gene name synonym)|uniprotkb:YNL189W(locus name)|uniprotkb:N1606(orf name)|uniprotkb:Karyopherin subunit alpha(gene name synonym)|uniprotkb:Karyopherin-60(gene name synonym)|uniprotkb:Serine-rich RNA polymerase I suppressor protein(gene name synonym)	psi-mi:actb_human(display_long)|uniprotkb:ACTB(gene name)|psi-mi:ACTB(display_short)|uniprotkb:Beta-actin(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550724|imex:IM-24995-3252	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014210.1|sgd:S000005133|dip:DIP-728N|mint:Q02821|ensemblfungi:YNL189W(gene)|ensemblfungi:YNL189W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0031144"(proteasome localization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042564"(NLS-dependent protein nuclear import complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|rcsb pdb:1BK5|rcsb pdb:1BK6|rcsb pdb:1EE4|rcsb pdb:1EE5|rcsb pdb:1UN0|rcsb pdb:1WA5|rcsb pdb:2C1T|rcsb pdb:4PVZ|rcsb pdb:4XZR|rcsb pdb:5H2W|rcsb pdb:5H2X|rcsb pdb:5T94	refseq:NP_001092.1|ensembl:ENSG00000075624(gene)|ensembl:ENST00000493945(transcript)|ensembl:ENST00000642480(transcript)|ensembl:ENST00000646664(transcript)|ensembl:ENST00000674681(transcript)|ensembl:ENST00000675515(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000785"(chromatin)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0001895"(retina homeostasis)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007409"(axonogenesis)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019894"(kinesin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0022898"(regulation of transmembrane transporter activity)|go:"GO:0030027"(lamellipodium)|go:"GO:0030424"(axon)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0030957"(Tat protein binding)|go:"GO:0031982"(vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034333"(adherens junction assembly)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043044"|go:"GO:0043296"(apical junction complex)|go:"GO:0044305"(calyx of Held)|go:"GO:0045176"(apical protein localization)|go:"GO:0045202"(synapse)|go:"GO:0048156"(tau protein binding)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048870"(cell motility)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051621"(regulation of norepinephrine uptake)|go:"GO:0051623"(positive regulation of norepinephrine uptake)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070160"(tight junction)|go:"GO:0070527"(platelet aggregation)|reactome:R-HSA-4420097|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0072562"(blood microparticle)|go:"GO:0072749"(cellular response to cytochalasin B)|go:"GO:0097433"(dense body)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098973"(structural constituent of postsynaptic actin cytoskeleton)|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0150111"(regulation of transepithelial transport)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P60709|rcsb pdb:3BYH|rcsb pdb:3D2U|rcsb pdb:3J82|rcsb pdb:3LUE|rcsb pdb:6ANU|rcsb pdb:6ICT|rcsb pdb:6ICV|rcsb pdb:6LTJ|rcsb pdb:6MBJ|rcsb pdb:6MBK|rcsb pdb:6MBL|rcsb pdb:6NBW|rcsb pdb:6OX0|rcsb pdb:6OX1|rcsb pdb:6OX2|rcsb pdb:6OX3|rcsb pdb:6OX4|rcsb pdb:6OX5|rcsb pdb:6V62|rcsb pdb:6V63|rcsb pdb:6WK1|rcsb pdb:6WK2|rcsb pdb:7AS4|reactome:R-HSA-1445148|reactome:R-HSA-190873|reactome:R-HSA-196025|reactome:R-HSA-2029482|reactome:R-HSA-3214847|reactome:R-HSA-389957|reactome:R-HSA-390450|reactome:R-HSA-3928662|reactome:R-HSA-3928665|reactome:R-HSA-418990|reactome:R-HSA-437239|reactome:R-HSA-446353|reactome:R-HSA-5250924|reactome:R-HSA-5626467|reactome:R-HSA-5663213|reactome:R-HSA-5663220|reactome:R-HSA-5674135|reactome:R-HSA-5689603|reactome:R-HSA-5696394|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8856828|reactome:R-HSA-9035034|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9662360|reactome:R-HSA-9662361|reactome:R-HSA-9664422|reactome:R-HSA-983231|reactome:R-HSA-445095|dip:DIP-29686N	-	crc64:8D3A0CB76F2E7C00	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:NyzC93xnBCb8DX/AH346lwg4u2A559292	rogid:Hoge1B8Pn56kvbNTpkSLsQuHwRc9606	intact-crc:F9BE91019709CE88|rigid:d5kT30yHU6iENIXi1DeN1T8yljU	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q08379	uniprotkb:Q02831	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	intact:EBI-31828|uniprotkb:D6W3T9|ensemblfungi:YPL077C	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:yp077_yeast(display_long)|uniprotkb:YPL077C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550728|imex:IM-24995-3253	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N	sgd:S000005998|refseq:NP_015248.1|dip:DIP-4022N|ensemblfungi:YPL077C(gene)|ensemblfungi:YPL077C_mRNA(transcript)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2017/05/26	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	rogid:yqOn4GWKNmFZ7UvGmyBEpgoyKlA559292	intact-crc:1E9E92B0E6634F80|rigid:MRpEjW2Eb4yYRpTVVIPB+VFwef8	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q03020	uniprotkb:P61289	intact:EBI-29901|uniprotkb:D6W3N2|ensemblfungi:YPL135W	intact:EBI-355546|uniprotkb:O35563|uniprotkb:P97373|uniprotkb:Q12920|uniprotkb:Q13172|uniprotkb:Q9BQD9|uniprotkb:A8K9A3|ensembl:ENSP00000466794	psi-mi:isu1_yeast(display_long)|uniprotkb:YPL135W(locus name)|uniprotkb:Iron sulfur cluster scaffold protein 1(gene name synonym)|uniprotkb:ISU1(gene name)|psi-mi:ISU1(display_short)|uniprotkb:NUA1(gene name synonym)	psi-mi:psme3_human(display_long)|uniprotkb:PSME3(gene name)|psi-mi:PSME3(display_short)|uniprotkb:Proteasome activator 28 subunit gamma(gene name synonym)|uniprotkb:Activator of multicatalytic protease subunit 3(gene name synonym)|uniprotkb:11S regulator complex subunit gamma(gene name synonym)|uniprotkb:Ki nuclear autoantigen(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550764|imex:IM-24995-3262	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015190.1|sgd:S000006056|dip:DIP-6556N|mint:Q03020|ensemblfungi:YPL135W(gene)|ensemblfungi:YPL135W_mRNA(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005506"(iron ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR002871(NIF system FeS cluster assembly, NifU, N-terminal)|interpro:IPR011339(ISC system FeS cluster assembly, IscU scaffold)|rcsb pdb:5T0V|rcsb pdb:5TRE|reactome:R-SCE-1362409	refseq:NP_005780.2|refseq:NP_789839.1|ensembl:ENSG00000131467(gene)|ensembl:ENST00000590720(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0008537"(proteasome activator complex)|go:"GO:0010950"(positive regulation of endopeptidase activity)|go:"GO:0016020"(membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0061133"(endopeptidase activator activity)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0097371"(MDM2/MDM4 family protein binding)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR003185(Proteasome activator pa28, REG alpha subunit)|interpro:IPR003186(Proteasome activator pa28, REG beta subunit)|interpro:IPR009077(Proteasome activator pa28, REG alpha/beta subunit)|interpro:IPR036252|interpro:IPR036996|interpro:IPR036997|mint:P61289|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168	-	crc64:E240845A27D2E9EE	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:zpPseOgZoK3cF+mCetzw05ct9Kc559292	rogid:6EQY2Kj3Juf++m4eBDzPWMgbC2k9606	intact-crc:A7F3E71F059120C2|rigid:dQyLm0cBx4VWs2S9MCLhvoIl1/4	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q03020	uniprotkb:P12268	intact:EBI-29901|uniprotkb:D6W3N2|ensemblfungi:YPL135W	intact:EBI-353389|uniprotkb:Q6LEF3|ensembl:ENSP00000321584	psi-mi:isu1_yeast(display_long)|uniprotkb:YPL135W(locus name)|uniprotkb:Iron sulfur cluster scaffold protein 1(gene name synonym)|uniprotkb:ISU1(gene name)|psi-mi:ISU1(display_short)|uniprotkb:NUA1(gene name synonym)	psi-mi:imdh2_human(display_long)|uniprotkb:IMPDH2(gene name)|psi-mi:IMPDH2(display_short)|uniprotkb:IMPD2(gene name synonym)|uniprotkb:Inosine-5'-monophosphate dehydrogenase type II(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550760|imex:IM-24995-3261	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015190.1|sgd:S000006056|dip:DIP-6556N|mint:Q03020|ensemblfungi:YPL135W(gene)|ensemblfungi:YPL135W_mRNA(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005506"(iron ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR002871(NIF system FeS cluster assembly, NifU, N-terminal)|interpro:IPR011339(ISC system FeS cluster assembly, IscU scaffold)|rcsb pdb:5T0V|rcsb pdb:5TRE|reactome:R-SCE-1362409	refseq:NP_000875.2|ensembl:ENSG00000178035(gene)|ensembl:ENST00000326739(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003938"(IMP dehydrogenase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006177"(GMP biosynthetic process)|go:"GO:0006183"(GTP biosynthetic process)|go:"GO:0007623"(circadian rhythm)|go:"GO:0016020"(membrane)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042802"(identical protein binding)|go:"GO:0046651"(lymphocyte proliferation)|go:"GO:0046872"(metal ion binding)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR001093(IMP dehydrogenase/GMP reductase)|interpro:IPR005990(IMP dehydrogenase)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR015875(IMP dehydrogenase / GMP reductase, conserved site)|mint:P12268|rcsb pdb:1B3O|rcsb pdb:1NF7|rcsb pdb:1NFB|rcsb pdb:6I0M|rcsb pdb:6I0O|rcsb pdb:6U8E|rcsb pdb:6U8N|rcsb pdb:6U8R|rcsb pdb:6U8S|rcsb pdb:6U9O|rcsb pdb:6UA2|rcsb pdb:6UA4|rcsb pdb:6UA5|rcsb pdb:6UAJ|rcsb pdb:6UC2|rcsb pdb:6UDO|rcsb pdb:6UDP|rcsb pdb:6UDQ|reactome:R-HSA-6798695|reactome:R-HSA-73817|reactome:R-HSA-9679191	-	crc64:E240845A27D2E9EE	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:zpPseOgZoK3cF+mCetzw05ct9Kc559292	rogid:qGPwBxhEgtYik3OetHZbpyktoLE9606	intact-crc:910D3974A07A5EEC|rigid:UUS0JBOozVlfgyupMRQItfMqcVw	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q03020	uniprotkb:P19012	intact:EBI-29901|uniprotkb:D6W3N2|ensemblfungi:YPL135W	intact:EBI-739566|uniprotkb:Q53XV8|uniprotkb:Q9BUG4|uniprotkb:B3KQY1|uniprotkb:B3KRA2|uniprotkb:E0CX14|ensembl:ENSP00000254043|ensembl:ENSP00000377546	psi-mi:isu1_yeast(display_long)|uniprotkb:YPL135W(locus name)|uniprotkb:Iron sulfur cluster scaffold protein 1(gene name synonym)|uniprotkb:ISU1(gene name)|psi-mi:ISU1(display_short)|uniprotkb:NUA1(gene name synonym)	psi-mi:k1c15_human(display_long)|uniprotkb:KRT15(gene name)|psi-mi:KRT15(display_short)|uniprotkb:KRTB(gene name synonym)|uniprotkb:Cytokeratin-15(gene name synonym)|uniprotkb:Keratin-15(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550756|imex:IM-24995-3260	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015190.1|sgd:S000006056|dip:DIP-6556N|mint:Q03020|ensemblfungi:YPL135W(gene)|ensemblfungi:YPL135W_mRNA(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005506"(iron ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR002871(NIF system FeS cluster assembly, NifU, N-terminal)|interpro:IPR011339(ISC system FeS cluster assembly, IscU scaffold)|rcsb pdb:5T0V|rcsb pdb:5TRE|reactome:R-SCE-1362409	refseq:NP_002266.2|ensembl:ENSG00000171346(gene)|ensembl:ENST00000254043(transcript)|ensembl:ENST00000393976(transcript)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0008544"(epidermis development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097110"(scaffold protein binding)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR039008|mint:P19012|reactome:R-HSA-6805567|reactome:R-HSA-6809371	-	crc64:E240845A27D2E9EE	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:zpPseOgZoK3cF+mCetzw05ct9Kc559292	rogid:WrZQBYQvrWcfrR5ojWXrXp6spPE9606	intact-crc:76EFF25596C3534F|rigid:v0AqN/Dy/CE4nd/2PzCo5gJ90m4	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P14373	uniprotkb:Q02831	intact:EBI-719493|uniprotkb:A2BE15|uniprotkb:Q5RJA8|uniprotkb:Q5ST26|uniprotkb:Q6LA73|uniprotkb:Q6NXR9|uniprotkb:Q9BZY6|uniprotkb:Q9UJL3|ensembl:ENSP00000383555|ensembl:ENSP00000392787|ensembl:ENSP00000405229|ensembl:ENSP00000414793|ensembl:ENSP00000366404	intact:EBI-31828|uniprotkb:D6W3T9|ensemblfungi:YPL077C	psi-mi:tri27_human(display_long)|uniprotkb:TRIM27(gene name)|psi-mi:TRIM27(display_short)|uniprotkb:RNF76(gene name synonym)|uniprotkb:RFP(gene name synonym)|uniprotkb:Ret finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 27(gene name synonym)|uniprotkb:RING finger protein 76(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM27(gene name synonym)	psi-mi:yp077_yeast(display_long)|uniprotkb:YPL077C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550740|imex:IM-24995-3256	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006501.1|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0090281"(negative regulation of calcium ion import)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR020457|interpro:IPR035791|interpro:IPR043136|mint:P14373|reactome:R-HSA-3232142|reactome:R-HSA-9635465|reactome:R-HSA-8948751|ensembl:ENSG00000204713(gene)|ensembl:ENSG00000215641(gene)|ensembl:ENSG00000229006(gene)|ensembl:ENSG00000234495(gene)|ensembl:ENSG00000237071(gene)|ensembl:ENST00000377199(transcript)|ensembl:ENST00000400720(transcript)|ensembl:ENST00000431123(transcript)|ensembl:ENST00000435528(transcript)|ensembl:ENST00000437160(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001650"(fibrillar center)|go:"GO:0002820"(negative regulation of adaptive immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)	sgd:S000005998|refseq:NP_015248.1|dip:DIP-4022N|ensemblfungi:YPL077C(gene)|ensemblfungi:YPL077C_mRNA(transcript)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:dsfH5OUghD8KSaTz1SFw9OYVTK49606	rogid:yqOn4GWKNmFZ7UvGmyBEpgoyKlA559292	intact-crc:F91D1D671375C36F|rigid:Q8eGCfFM3ftJdYSF/cdD+C4spWQ	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q7Z6G3-2	uniprotkb:Q02831	intact:EBI-10172876|ensembl:ENSP00000457354|intact:EBI-14062040	intact:EBI-31828|uniprotkb:D6W3T9|ensemblfungi:YPL077C	psi-mi:q7z6g3-2(display_long)|uniprotkb:EFCBP2(gene name synonym)|uniprotkb:Neuronal calcium-binding protein 2(gene name synonym)|uniprotkb:Synaptotagmin-interacting protein 2(gene name synonym)|uniprotkb:NECAB2(gene name)|psi-mi:NECAB2(display_short)	psi-mi:yp077_yeast(display_long)|uniprotkb:YPL077C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550748|imex:IM-24995-3258	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000103154(gene)|ensembl:ENST00000565691(transcript)|uniprotkb:Q7Z6G3-2(isoform-parent)|intact:EBI-950070(isoform-parent)	sgd:S000005998|refseq:NP_015248.1|dip:DIP-4022N|ensemblfungi:YPL077C(gene)|ensemblfungi:YPL077C_mRNA(transcript)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:4S7oIx6h+mKzV3EPxqcfMNqaNko9606	rogid:yqOn4GWKNmFZ7UvGmyBEpgoyKlA559292	intact-crc:E760BA40B9C2DC6B|rigid:NS1rCXHrw1I2d8hIkI/N6uIQDic	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P37198	uniprotkb:Q02831	intact:EBI-347978|intact:EBI-28983799|ensembl:ENSP00000305503|ensembl:ENSP00000407331|ensembl:ENSP00000471191|ensembl:ENSP00000473192|uniprotkb:Q6GTM2|uniprotkb:Q503A4|uniprotkb:Q96C43|uniprotkb:Q9NSL1|uniprotkb:B3KWU5	intact:EBI-31828|uniprotkb:D6W3T9|ensemblfungi:YPL077C	psi-mi:nup62_human(display_long)|uniprotkb:NUP62(gene name)|psi-mi:NUP62(display_short)|uniprotkb:62 kDa nucleoporin(gene name synonym)|uniprotkb:Nucleoporin Nup62(gene name synonym)	psi-mi:yp077_yeast(display_long)|uniprotkb:YPL077C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550744|imex:IM-24995-3257	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_714941.1|ensembl:ENSG00000213024(gene)|ensembl:ENST00000352066(transcript)|ensembl:ENST00000422090(transcript)|ensembl:ENST00000596217(transcript)|ensembl:ENST00000597029(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005642"(annulate lamellae)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007100"(mitotic centrosome separation)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007569"(cell aging)|go:"GO:0008219"(cell death)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0003682"(chromatin binding)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0019894"(kinesin binding)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042306"(regulation of protein import into nucleus)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043069"(negative regulation of programmed cell death)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045742"(positive regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046578"(regulation of Ras protein signal transduction)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0046601"(positive regulation of centriole replication)|go:"GO:0051028"(mRNA transport)|go:"GO:0051425"(PTB domain binding)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0072686"(mitotic spindle)|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|go:"GO:0090543"(Flemming body)|go:"GO:0098534"(centriole assembly)|go:"GO:1903438"(positive regulation of mitotic cytokinetic process)|go:"GO:1904781"(positive regulation of protein localization to centrosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR007758(Nucleoporin, Nsp1-like, C-terminal)|interpro:IPR026010|interpro:IPR033072|mint:P37198|rcsb pdb:2H4D|rcsb pdb:5IJN|rcsb pdb:5IJO|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|refseq:NP_714940.1|refseq:NP_001180286.1|refseq:NP_036478.2|refseq:NP_057637.2|ensembl:ENSP00000305503|ensembl:ENSP00000407331|ensembl:ENSP00000471191|ensembl:ENSP00000473192|dip:DIP-29749N	sgd:S000005998|refseq:NP_015248.1|dip:DIP-4022N|ensemblfungi:YPL077C(gene)|ensemblfungi:YPL077C_mRNA(transcript)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:v7mvKvTtVEnLMwcpUZIcdAzge009606	rogid:yqOn4GWKNmFZ7UvGmyBEpgoyKlA559292	intact-crc:D902DDC473BB322F|rigid:Iu3MYsKsSKmQS3zrsuXCmq0qeY4	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q02939	uniprotkb:E9PFK9	intact:EBI-2345544|uniprotkb:D6W3P5|uniprotkb:P87331|ensemblfungi:YPL122C	intact:EBI-11523104|ensembl:ENSP00000403429	psi-mi:tfb2_yeast(display_long)|uniprotkb:RNA polymerase II transcription factor B subunit 2(gene name synonym)|uniprotkb:YPL122C(locus name)|uniprotkb:TFB2(gene name)|psi-mi:TFB2(display_short)|uniprotkb:RNA polymerase II transcription factor B p52 subunit(gene name synonym)|uniprotkb:RNA polymerase II transcription factor B 52 kDa subunit(gene name synonym)	psi-mi:e9pfk9_human(display_long)|uniprotkb:RABGEF1(gene name)|psi-mi:RABGEF1(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550752|imex:IM-24995-3259	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015203.1|sgd:S000006043|dip:DIP-5783N|mint:Q02939|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-5696395|reactome:R-SCE-674695|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-72086|reactome:R-SCE-73772|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075|ensemblfungi:YPL122C(gene)|ensemblfungi:YPL122C_mRNA(transcript)|go:"GO:0000112"(nucleotide-excision repair factor 3 complex)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR004598(Transcription factor Tfb2)|interpro:IPR040662|rcsb pdb:3DGP|rcsb pdb:3DOM|rcsb pdb:5FMF|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:5SVA|rcsb pdb:6GYM|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O4K|rcsb pdb:7O4L|rcsb pdb:7O72|rcsb pdb:7O73	ensembl:ENSG00000154710(gene)|ensembl:ENST00000439720(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|interpro:IPR002653(Zinc finger, A20-type)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR037191|interpro:IPR041545	-	crc64:9E440B566396A95A	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:TJC5kOBM7mOJLttEEiSqXvlVyXc559292	rogid:JDHW8cuCB2z39j6a+LlkARnLfYo9606	intact-crc:D9BC60B615193013|rigid:Q8lrt3YrZkk3lWQRn1kFPM2jTyE	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P63279	uniprotkb:Q03373	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	intact:EBI-34019|uniprotkb:D6VTA3|ensemblfungi:YDR480W	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:dig2_yeast(display_long)|uniprotkb:DIG2(gene name)|psi-mi:DIG2(display_short)|uniprotkb:Regulator of sterile twelve 2(gene name synonym)|uniprotkb:Regulator of STE12 protein 2(gene name synonym)|uniprotkb:RST2(gene name synonym)|uniprotkb:D8035.23(orf name)|uniprotkb:YDR480W(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550788|imex:IM-24995-3268	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N	sgd:S000002888|refseq:NP_010768.1|mint:Q03373|dip:DIP-1292N|ensemblfungi:YDR480W(gene)|ensemblfungi:YDR480W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0008134"(transcription factor binding)|go:"GO:0046020"(negative regulation of transcription from RNA polymerase II promoter by pheromones)|go:"GO:1990526"(Ste12p-Dig1p-Dig2p complex)|go:"GO:2000218"(negative regulation of invasive growth in response to glucose limitation)|go:"GO:2000221"(negative regulation of pseudohyphal growth)	-	-	crc64:8E71278ED6D3A912	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	rogid:Uh6OsQDXtmnLKMAEZHl/NTKCEYY559292	intact-crc:DAC7DD6A00E501CF|rigid:ijMMvi5+BnGuI045ugOrZ5wp46A	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O14641	uniprotkb:Q03338	intact:EBI-740850|ensembl:ENSP00000005340|uniprotkb:Q53XM0|uniprotkb:D3DTN3	intact:EBI-421|uniprotkb:D6VT97|ensemblfungi:YDR473C	psi-mi:dvl2_human(display_long)|uniprotkb:DSH homolog 2(gene name synonym)|uniprotkb:DVL2(gene name)|psi-mi:DVL2(display_short)	psi-mi:prp3_yeast(display_long)|uniprotkb:PRP3(gene name)|psi-mi:PRP3(display_short)|uniprotkb:RNA3(gene name synonym)|uniprotkb:YDR473C(locus name)|uniprotkb:D8035.16(orf name)|uniprotkb:Pre-mRNA-splicing factor 3(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550784|imex:IM-24995-3267	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004413.1|ensembl:ENSG00000004975(gene)|ensembl:ENST00000005340(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005109"(frizzled binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0007507"(heart development)|go:"GO:0016235"(aggresome)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044340"(canonical Wnt signaling pathway involved in regulation of cell proliferation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0150012"(positive regulation of neuron projection arborization)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008341(Dishevelled-2 region)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:O14641|rcsb pdb:2REY|rcsb pdb:3CBX|rcsb pdb:3CBY|rcsb pdb:3CBZ|rcsb pdb:3CC0|rcsb pdb:4WIP|rcsb pdb:5LNP|rcsb pdb:5SUY|rcsb pdb:5SUZ|rcsb pdb:6IW3|rcsb pdb:6JCK|reactome:R-HSA-201681|reactome:R-HSA-201688|reactome:R-HSA-2028269|reactome:R-HSA-4086400|reactome:R-HSA-4608870|reactome:R-HSA-4641258|reactome:R-HSA-4641262|reactome:R-HSA-5099900|reactome:R-HSA-5368598|reactome:R-HSA-5663220|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9673324|ensembl:ENSP00000005340|dip:DIP-34433N	sgd:S000002881|refseq:NP_010761.3|ensemblfungi:YDR473C(gene)|ensemblfungi:YDR473C_mRNA(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|interpro:IPR010541(Protein of unknown function DUF1115)|interpro:IPR013881(Pre-mRNA-splicing factor 3)|interpro:IPR027104|rcsb pdb:3JCM|rcsb pdb:4YHU|rcsb pdb:4YHV|rcsb pdb:4YHW|rcsb pdb:5GAN|rcsb pdb:5GAP|rcsb pdb:5NRL|rcsb pdb:5ZWM|rcsb pdb:5ZWO|dip:DIP-5266N|mint:Q03338	-	-	crc64:E977FD9F708BDD91	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:2Vdc8oRnT4Mz/j+EXQXrL3AszOc9606	rogid:KE0Y/kRXTq9LXt4PGsKnRcY7Sqg559292	intact-crc:1F0C5D51B8E8BDE3|rigid:3nza4C1jHUkLd7cvGrIQJ1bmWA4	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q03063	uniprotkb:P63279	intact:EBI-29752|uniprotkb:D6W3W5|ensemblfungi:YPL049C	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	psi-mi:dig1_yeast(display_long)|uniprotkb:DIG1(gene name)|psi-mi:DIG1(display_short)|uniprotkb:Regulator of sterile twelve 1(gene name synonym)|uniprotkb:Regulator of STE12 protein 1(gene name synonym)|uniprotkb:RST1(gene name synonym)|uniprotkb:P7102.02(orf name)|uniprotkb:YPL049C(locus name)	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550768|imex:IM-24995-3263	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005970|refseq:NP_015276.1|dip:DIP-1291N|mint:Q03063|ensemblfungi:YPL049C(gene)|ensemblfungi:YPL049C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0008134"(transcription factor binding)|go:"GO:0046020"(negative regulation of transcription from RNA polymerase II promoter by pheromones)|go:"GO:1900240"(negative regulation of phenotypic switching)|go:"GO:1990526"(Ste12p-Dig1p-Dig2p complex)|go:"GO:1990527"(Tec1p-Ste12p-Dig1p complex)|go:"GO:2000218"(negative regulation of invasive growth in response to glucose limitation)|go:"GO:2000221"(negative regulation of pseudohyphal growth)	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N	-	crc64:2D27F9878BFADD30	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Qt+hpsHdt+kIqMB+GKG4AYKLgOQ559292	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	intact-crc:72BD2756417AFFE9|rigid:Umtwr71MyQ/+i5yADc7EBy2nXJs	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q03063	uniprotkb:P23497-2	intact:EBI-29752|uniprotkb:D6W3W5|ensemblfungi:YPL049C	intact:EBI-6589365|ensembl:ENSP00000386404	psi-mi:dig1_yeast(display_long)|uniprotkb:DIG1(gene name)|psi-mi:DIG1(display_short)|uniprotkb:Regulator of sterile twelve 1(gene name synonym)|uniprotkb:Regulator of STE12 protein 1(gene name synonym)|uniprotkb:RST1(gene name synonym)|uniprotkb:P7102.02(orf name)|uniprotkb:YPL049C(locus name)	psi-mi:p23497-2(display_long)|uniprotkb:SP100(isoform synonym)|uniprotkb:SP100(gene name)|psi-mi:SP100(display_short)|uniprotkb:Nuclear dot-associated Sp100 protein(gene name synonym)|uniprotkb:Speckled 100 kDa(gene name synonym)|uniprotkb:SP100A(isoform synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550776|imex:IM-24995-3265	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005970|refseq:NP_015276.1|dip:DIP-1291N|mint:Q03063|ensemblfungi:YPL049C(gene)|ensemblfungi:YPL049C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0008134"(transcription factor binding)|go:"GO:0046020"(negative regulation of transcription from RNA polymerase II promoter by pheromones)|go:"GO:1900240"(negative regulation of phenotypic switching)|go:"GO:1990526"(Ste12p-Dig1p-Dig2p complex)|go:"GO:1990527"(Tec1p-Ste12p-Dig1p complex)|go:"GO:2000218"(negative regulation of invasive growth in response to glucose limitation)|go:"GO:2000221"(negative regulation of pseudohyphal growth)	intact:EBI-751145(isoform-parent)|uniprotkb:P23497-2(isoform-parent)|ensembl:ENSG00000067066(gene)|ensembl:ENST00000409341(transcript)	-	crc64:2D27F9878BFADD30	isoform-comment:Major isoform.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Qt+hpsHdt+kIqMB+GKG4AYKLgOQ559292	rogid:HrcogLANB///4vkSYtZ7OtzOb2k9606	intact-crc:7CDE4D90C96B551F|rigid:gd24i9x60yUV9LMH26ANwDUHUoo	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q03063	uniprotkb:O14641	intact:EBI-29752|uniprotkb:D6W3W5|ensemblfungi:YPL049C	intact:EBI-740850|ensembl:ENSP00000005340|uniprotkb:Q53XM0|uniprotkb:D3DTN3	psi-mi:dig1_yeast(display_long)|uniprotkb:DIG1(gene name)|psi-mi:DIG1(display_short)|uniprotkb:Regulator of sterile twelve 1(gene name synonym)|uniprotkb:Regulator of STE12 protein 1(gene name synonym)|uniprotkb:RST1(gene name synonym)|uniprotkb:P7102.02(orf name)|uniprotkb:YPL049C(locus name)	psi-mi:dvl2_human(display_long)|uniprotkb:DSH homolog 2(gene name synonym)|uniprotkb:DVL2(gene name)|psi-mi:DVL2(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550772|imex:IM-24995-3264	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005970|refseq:NP_015276.1|dip:DIP-1291N|mint:Q03063|ensemblfungi:YPL049C(gene)|ensemblfungi:YPL049C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0008134"(transcription factor binding)|go:"GO:0046020"(negative regulation of transcription from RNA polymerase II promoter by pheromones)|go:"GO:1900240"(negative regulation of phenotypic switching)|go:"GO:1990526"(Ste12p-Dig1p-Dig2p complex)|go:"GO:1990527"(Tec1p-Ste12p-Dig1p complex)|go:"GO:2000218"(negative regulation of invasive growth in response to glucose limitation)|go:"GO:2000221"(negative regulation of pseudohyphal growth)	refseq:NP_004413.1|ensembl:ENSG00000004975(gene)|ensembl:ENST00000005340(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005109"(frizzled binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0007507"(heart development)|go:"GO:0016235"(aggresome)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044340"(canonical Wnt signaling pathway involved in regulation of cell proliferation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0150012"(positive regulation of neuron projection arborization)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008341(Dishevelled-2 region)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:O14641|rcsb pdb:2REY|rcsb pdb:3CBX|rcsb pdb:3CBY|rcsb pdb:3CBZ|rcsb pdb:3CC0|rcsb pdb:4WIP|rcsb pdb:5LNP|rcsb pdb:5SUY|rcsb pdb:5SUZ|rcsb pdb:6IW3|rcsb pdb:6JCK|reactome:R-HSA-201681|reactome:R-HSA-201688|reactome:R-HSA-2028269|reactome:R-HSA-4086400|reactome:R-HSA-4608870|reactome:R-HSA-4641258|reactome:R-HSA-4641262|reactome:R-HSA-5099900|reactome:R-HSA-5368598|reactome:R-HSA-5663220|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9673324|ensembl:ENSP00000005340|dip:DIP-34433N	-	crc64:2D27F9878BFADD30	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Qt+hpsHdt+kIqMB+GKG4AYKLgOQ559292	rogid:2Vdc8oRnT4Mz/j+EXQXrL3AszOc9606	intact-crc:187FC350E25C5371|rigid:/wBHfqjPn6GO0FbXwA2Su0E5RvM	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q03262	uniprotkb:O43809	intact:EBI-27609|uniprotkb:D6W0A5|ensemblfungi:YMR278W	intact:EBI-355720|uniprotkb:Q6IB85|uniprotkb:Q6NE84|ensembl:ENSP00000300291	psi-mi:pgm3_yeast(display_long)|uniprotkb:PRM15(gene name)|psi-mi:PRM15(display_short)|uniprotkb:PGM3(gene name synonym)|uniprotkb:Phosphoglucomutase 3(gene name synonym)|uniprotkb:YM8021.04(orf name)|uniprotkb:YMR278W(locus name)	psi-mi:cpsf5_human(display_long)|uniprotkb:NUDT21(gene name)|psi-mi:NUDT21(display_short)|uniprotkb:CFIM25(gene name synonym)|uniprotkb:CPSF25(gene name synonym)|uniprotkb:CPSF5(gene name synonym)|uniprotkb:Cleavage and polyadenylation specificity factor 25 kDa subunit(gene name synonym)|uniprotkb:Nucleoside diphosphate-linked moiety X motif 21(gene name synonym)|uniprotkb:Cleavage factor Im complex 25 kDa subunit(gene name synonym)|uniprotkb:Nudix hydrolase 21(gene name synonym)|uniprotkb:Pre-mRNA cleavage factor Im 68 kDa subunit(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550780|imex:IM-24995-3266	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000004891|refseq:NP_014005.1|reactome:R-SCE-3322077|reactome:R-SCE-71336|reactome:R-SCE-6798695|dip:DIP-5066N|reactome:R-SCE-70171|reactome:R-SCE-70221|reactome:R-SCE-70370|interpro:IPR036900|interpro:IPR016066(Alpha-D-phosphohexomutase, conserved site)|ensemblfungi:YMR278W(gene)|ensemblfungi:YMR278W_mRNA(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006148"(inosine catabolic process)|go:"GO:0006166"(purine ribonucleoside salvage)|go:"GO:0008973"(phosphopentomutase activity)|go:"GO:0046115"(guanosine catabolic process)|interpro:IPR005843(Alpha-D-phosphohexomutase, C-terminal)|interpro:IPR005844(Alpha-D-phosphohexomutase, alpha/beta/alpha domain I)|interpro:IPR005845(Alpha-D-phosphohexomutase, alpha/beta/alpha domain II)|interpro:IPR005846(Alpha-D-phosphohexomutase, alpha/beta/alpha domain III)|interpro:IPR016055(Alpha-D-phosphohexomutase, alpha/beta/alpha I, II and III)	refseq:NP_008937.1|ensembl:ENSG00000167005(gene)|ensembl:ENST00000300291(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0005849"(mRNA cleavage factor complex)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0006397"(mRNA processing)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0031439"(positive regulation of mRNA cleavage)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0042382"(paraspeckles)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051290"(protein heterotetramerization)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|go:"GO:0110104"(mRNA alternative polyadenylation)|go:"GO:1900365"(positive regulation of mRNA polyadenylation)|go:"GO:1990120"(messenger ribonucleoprotein complex assembly)|go:"GO:2000738"(positive regulation of stem cell differentiation)|go:"GO:2000975"(positive regulation of pro-B cell differentiation)|interpro:IPR000086(NUDIX hydrolase, core)|interpro:IPR015797(NUDIX)|interpro:IPR016706(Cleavage and polyadenylation specificity factor, 25 kDa subunit)|mint:O43809|rcsb pdb:2CL3|rcsb pdb:2J8Q|rcsb pdb:3BAP|rcsb pdb:3BHO|rcsb pdb:3MDG|rcsb pdb:3MDI|rcsb pdb:3N9U|rcsb pdb:3P5T|rcsb pdb:3P6Y|rcsb pdb:3Q2S|rcsb pdb:3Q2T|rcsb pdb:5R4P|rcsb pdb:5R4Q|rcsb pdb:5R4R|rcsb pdb:5R4S|rcsb pdb:5R4T|rcsb pdb:5R4U|rcsb pdb:5R64|rcsb pdb:5R65|rcsb pdb:5R66|rcsb pdb:5R67|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-77595|dip:DIP-42502N	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:hEeb0XLedLqmf04ufZaiMNcwQXE559292	rogid:Acad4mYVuS+Eox+X2CH8PYUkGAA9606	intact-crc:4E800EAC1B542AE5|rigid:XWdqPBSj+MwrHkF4/LloWEX52fE	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q03920	uniprotkb:O43186	intact:EBI-31378|uniprotkb:D6VSC3|ensemblfungi:YDR140W	intact:EBI-748171|uniprotkb:Q0QD45|ensembl:ENSP00000221996|ensembl:ENSP00000445565	psi-mi:mtq2_yeast(display_long)|uniprotkb:MTQ2(gene name)|psi-mi:MTQ2(display_short)|uniprotkb:MTC6(gene name synonym)|uniprotkb:"N(5)-glutamine methyltransferase MTQ2"(gene name synonym)|uniprotkb:YDR140W(locus name)	psi-mi:crx_human(display_long)|uniprotkb:CRX(gene name)|psi-mi:CRX(display_short)|uniprotkb:CORD2(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550816|imex:IM-24995-3275	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010424.3|sgd:S000002547|dip:DIP-1755N|mint:Q03920|ensemblfungi:YDR140W(gene)|ensemblfungi:YDR140W_mRNA(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006417"(regulation of translation)|go:"GO:0008276"(protein methyltransferase activity)|go:"GO:0008757"(S-adenosylmethionine-dependent methyltransferase activity)|go:"GO:0018364"(peptidyl-glutamine methylation)|go:"GO:0035657"(eRF1 methyltransferase complex)|go:"GO:0102559"("protein-(glutamine-N5) methyltransferase activity")|interpro:IPR002052(N-6 adenine-specific DNA methylase, conserved site)|interpro:IPR004557(Putative methylase)|interpro:IPR007848(Methyltransferase small)|interpro:IPR029063|reactome:R-SCE-156581|reactome:R-SCE-72764	refseq:NP_000545.1|ensembl:ENSG00000105392(gene)|ensembl:ENST00000221996(transcript)|ensembl:ENST00000539067(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007601"(visual perception)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050896"(response to stimulus)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013851(Transcription factor Otx, C-terminal)|interpro:IPR017970	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:pu/ERTe9ojnsy8nxRKkRA+sHq80559292	rogid:v/bkO/0iLzq1Q2HtieWQQ40RF9M9606	intact-crc:DB8004676BED59F0|rigid:jK1E8/cYJFzaXPokj4t5pjA2Fhg	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P43355	uniprotkb:Q03782	intact:EBI-740978|ensembl:ENSP00000349085|uniprotkb:O00346|uniprotkb:B2RC81	intact:EBI-627|uniprotkb:D6VSM1|ensemblfungi:YDR240C	psi-mi:maga1_human(display_long)|uniprotkb:MAGE-1 antigen(gene name synonym)|uniprotkb:Antigen MZ2-E(gene name synonym)|uniprotkb:Cancer/testis antigen 1.1(gene name synonym)|uniprotkb:MAGEA1(gene name)|psi-mi:MAGEA1(display_short)|uniprotkb:MAGE1(gene name synonym)|uniprotkb:MAGE1A(gene name synonym)	psi-mi:snu56_yeast(display_long)|uniprotkb:YDR240C(locus name)|uniprotkb:SNU56(gene name)|psi-mi:SNU56(display_short)|uniprotkb:MUD10(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550812|imex:IM-24995-3274	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004979.3|ensembl:ENSG00000198681(gene)|ensembl:ENST00000356661(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|interpro:IPR002190(MAGE protein)|interpro:IPR021072|interpro:IPR030093|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|rcsb pdb:1W72|rcsb pdb:3BO8|dip:DIP-54794N	sgd:S000002648|refseq:NP_010526.1|dip:DIP-6514N|mint:Q03782|ensemblfungi:YDR240C(gene)|ensemblfungi:YDR240C_mRNA(transcript)|go:"GO:0000243"(commitment complex)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005685"(U1 snRNP)|go:"GO:0071004"(U2-type prespliceosome)|interpro:IPR043954|rcsb pdb:5ZWN|rcsb pdb:6G90|rcsb pdb:6N7P|rcsb pdb:6N7R|rcsb pdb:6N7X	-	crc64:544EEB1F9F4E9D33	crc64:5E0C7A1FD577808F	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:6XW3mnTNM3yvOtXmiFbU8Uz3hjA9606	rogid:gz3aUh/8pFF7Yn8XS9gdhSWrVNs559292	intact-crc:F66335609AD8C2CA|rigid:mWzhpwpq6fEPBATJay05BGCidGM	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q03718	uniprotkb:P63279	intact:EBI-27756|uniprotkb:D6VZF1|ensemblfungi:YML023C	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	psi-mi:nse5_yeast(display_long)|uniprotkb:YML023C(locus name)|uniprotkb:NSE5(gene name)|psi-mi:NSE5(display_short)	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550808|imex:IM-24995-3273	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013689.1|sgd:S000004485|dip:DIP-4547N|ensemblfungi:YML023C(gene)|ensemblfungi:YML023C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0016925"(protein sumoylation)|go:"GO:0030915"(Smc5-Smc6 complex)|interpro:IPR014803(DNA repair protein Nse5)|rcsb pdb:7LTO	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N	-	crc64:6680A04D91E537DD	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:xDmbHW4E/uX4NGGcDCMXTnUDQGk559292	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	intact-crc:65EA89CF0FBD4798|rigid:uLlN/Eozbz0vf94J6UEzlw91zWI	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q03373	uniprotkb:P31947	intact:EBI-34019|uniprotkb:D6VTA3|ensemblfungi:YDR480W	intact:EBI-476295|uniprotkb:Q6FH30|uniprotkb:Q6FH51|uniprotkb:Q96DH0|ensembl:ENSP00000340989|intact:EBI-28970316	psi-mi:dig2_yeast(display_long)|uniprotkb:DIG2(gene name)|psi-mi:DIG2(display_short)|uniprotkb:Regulator of sterile twelve 2(gene name synonym)|uniprotkb:Regulator of STE12 protein 2(gene name synonym)|uniprotkb:RST2(gene name synonym)|uniprotkb:D8035.23(orf name)|uniprotkb:YDR480W(locus name)	psi-mi:1433s_human(display_long)|uniprotkb:Stratifin(gene name synonym)|uniprotkb:Epithelial cell marker protein 1(gene name synonym)|uniprotkb:HME1(gene name synonym)|uniprotkb:SFN(gene name)|psi-mi:SFN(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550792|imex:IM-24995-3269	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002888|refseq:NP_010768.1|mint:Q03373|dip:DIP-1292N|ensemblfungi:YDR480W(gene)|ensemblfungi:YDR480W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0008134"(transcription factor binding)|go:"GO:0046020"(negative regulation of transcription from RNA polymerase II promoter by pheromones)|go:"GO:1990526"(Ste12p-Dig1p-Dig2p complex)|go:"GO:2000218"(negative regulation of invasive growth in response to glucose limitation)|go:"GO:2000221"(negative regulation of pseudohyphal growth)	ensembl:ENSP00000340989|go:"GO:0010839"(negative regulation of keratinocyte proliferation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0031424"(keratinization)|ensembl:ENSG00000175793(gene)|go:"GO:0042802"(identical protein binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|ensembl:ENST00000339276(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0045606"(positive regulation of epidermal cell differentiation)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000308(14-3-3 protein)|go:"GO:0003334"(keratinocyte development)|interpro:IPR023409|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007165"(signal transduction)|go:"GO:0008426"(protein kinase C inhibitor activity)|interpro:IPR023410|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0010482"(regulation of epidermal cell division)|interpro:IPR036815|interpro:IPR037435|mint:P31947|rcsb pdb:1YWT|rcsb pdb:3IQJ|rcsb pdb:3IQU|rcsb pdb:3IQV|rcsb pdb:3LW1|rcsb pdb:3MHR|rcsb pdb:3O8I|rcsb pdb:3P1N|rcsb pdb:3P1O|rcsb pdb:3P1P|rcsb pdb:3P1Q|rcsb pdb:3P1R|rcsb pdb:3P1S|rcsb pdb:3SMK|rcsb pdb:3SML|rcsb pdb:3SMM|rcsb pdb:3SMN|rcsb pdb:3SMO|rcsb pdb:3SP5|rcsb pdb:3SPR|rcsb pdb:3T0L|rcsb pdb:3T0M|rcsb pdb:3U9X|rcsb pdb:3UX0|rcsb pdb:4DAT|rcsb pdb:4DAU|rcsb pdb:4DHM|rcsb pdb:4DHN|rcsb pdb:4DHO|rcsb pdb:4DHP|rcsb pdb:4DHQ|rcsb pdb:4DHR|rcsb pdb:4DHS|rcsb pdb:4DHT|rcsb pdb:4DHU|rcsb pdb:4FL5|rcsb pdb:4FR3|rcsb pdb:4IEA|rcsb pdb:4JC3|rcsb pdb:4JDD|rcsb pdb:4QLI|rcsb pdb:4Y32|rcsb pdb:4Y3B|rcsb pdb:4Y5I|rcsb pdb:5BTV|rcsb pdb:5HF3|rcsb pdb:1YZ5|rcsb pdb:5LTW|rcsb pdb:5LU1|rcsb pdb:5LU2|rcsb pdb:5MHC|rcsb pdb:5MOC|rcsb pdb:5MXO|rcsb pdb:7O34|rcsb pdb:7O3A|rcsb pdb:7O3F|rcsb pdb:7O3P|rcsb pdb:7O3Q|rcsb pdb:7NZV|rcsb pdb:7O3R|rcsb pdb:7O3S|rcsb pdb:7O57|rcsb pdb:7O59|rcsb pdb:7O5A|rcsb pdb:7O5C|rcsb pdb:7O5D|rcsb pdb:7O5F|rcsb pdb:7O5G|rcsb pdb:7O5O|rcsb pdb:7O5P|rcsb pdb:7O5S|rcsb pdb:7O5U|rcsb pdb:7O5X|rcsb pdb:7O6F|rcsb pdb:7O6G|rcsb pdb:7O6I|rcsb pdb:7O6J|rcsb pdb:7O6K|rcsb pdb:7O6M|rcsb pdb:7O6O|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-5625740|reactome:R-HSA-5628897|rcsb pdb:6GHP|rcsb pdb:6HHP|rcsb pdb:6HKB|rcsb pdb:6HKF|rcsb pdb:6HMT|rcsb pdb:6G8Q|rcsb pdb:6HMU|rcsb pdb:6HN2|rcsb pdb:6NV2|rcsb pdb:6QDR|rcsb pdb:6QDS|rcsb pdb:6QDT|rcsb pdb:6QDU|rcsb pdb:6QHL|rcsb pdb:6QHM|rcsb pdb:6QIU|rcsb pdb:6QZR|rcsb pdb:6QZS|rcsb pdb:6R5L|rcsb pdb:6RHC|rcsb pdb:6RJL|rcsb pdb:6RJQ|rcsb pdb:6RJZ|rcsb pdb:6RK8|rcsb pdb:6RKI|rcsb pdb:6RKK|rcsb pdb:6RKM|rcsb pdb:6RL3|rcsb pdb:6RL4|rcsb pdb:6RL6|rcsb pdb:6RM5|rcsb pdb:6RM7|rcsb pdb:6RP6|rcsb pdb:6RWH|rcsb pdb:6RWI|rcsb pdb:5MYC|rcsb pdb:5N5R|rcsb pdb:5N5T|rcsb pdb:5N5W|rcsb pdb:5N75|rcsb pdb:5OEG|rcsb pdb:5OEH|rcsb pdb:5OK9|rcsb pdb:5OKF|rcsb pdb:5OM0|rcsb pdb:5OMA|rcsb pdb:6FAU|rcsb pdb:6FAV|rcsb pdb:6FAW|rcsb pdb:6FBB|rcsb pdb:6FBW|rcsb pdb:6FBY|rcsb pdb:6FCP|rcsb pdb:6FI4|rcsb pdb:6FI5|rcsb pdb:6G6X|rcsb pdb:6G8I|rcsb pdb:5MY9|rcsb pdb:6G8J|rcsb pdb:6G8K|rcsb pdb:6G8L|rcsb pdb:6G8P|rcsb pdb:6RWS|rcsb pdb:6TJM|rcsb pdb:6TL3|rcsb pdb:6RWU|rcsb pdb:6TLF|rcsb pdb:6TLG|rcsb pdb:6TM7|rcsb pdb:6TWZ|rcsb pdb:6W0L|rcsb pdb:6XWD|rcsb pdb:6XXC|rcsb pdb:6XY5|rcsb pdb:6Y18|rcsb pdb:6Y1D|rcsb pdb:6Y1J|rcsb pdb:6RX2|rcsb pdb:6S39|rcsb pdb:6S3C|rcsb pdb:6S40|rcsb pdb:6Y3M|rcsb pdb:6Y3O|rcsb pdb:6Y3R|rcsb pdb:6Y3S|rcsb pdb:6Y3V|rcsb pdb:6Y3W|rcsb pdb:6Y40|rcsb pdb:6S9Q|rcsb pdb:6Y44|rcsb pdb:6SIN|rcsb pdb:6Y58|rcsb pdb:6SIO|rcsb pdb:6Y7T|rcsb pdb:6SIP|rcsb pdb:6Y8A|rcsb pdb:6Y8B|rcsb pdb:6Y8D|rcsb pdb:6SIQ|rcsb pdb:6Y8E|rcsb pdb:6YE9|rcsb pdb:6YIA|rcsb pdb:6SLV|rcsb pdb:6YIB|rcsb pdb:6YIC|rcsb pdb:6YLU|rcsb pdb:6YOW|rcsb pdb:6YOX|rcsb pdb:6YOY|rcsb pdb:6YP2|rcsb pdb:6YP3|rcsb pdb:6YP8|rcsb pdb:6SLW|rcsb pdb:6SLX|rcsb pdb:6T5F|rcsb pdb:6T5H|rcsb pdb:6T80|rcsb pdb:6TCH|rcsb pdb:6YPL|rcsb pdb:6YPY|rcsb pdb:6YQ2|rcsb pdb:6ZCJ|rcsb pdb:7AEW|rcsb pdb:7AOG|rcsb pdb:7AXN|rcsb pdb:7AYF|rcsb pdb:7AZ1|rcsb pdb:7AZ2|rcsb pdb:7BDP|rcsb pdb:7BDT|rcsb pdb:7BDY|rcsb pdb:7BFW|rcsb pdb:7BG3|rcsb pdb:7BGQ|rcsb pdb:7BGR|rcsb pdb:7BGV|rcsb pdb:7BGW|rcsb pdb:7BI3|rcsb pdb:7BIQ|rcsb pdb:7BIY|rcsb pdb:7BJF|rcsb pdb:7BJL|rcsb pdb:7BJW|rcsb pdb:7BKH|rcsb pdb:7NFW|rcsb pdb:7NIF|rcsb pdb:7NIG|rcsb pdb:7NIX|rcsb pdb:7NJ6|rcsb pdb:7NJ8|rcsb pdb:7NJ9|rcsb pdb:7NJA|rcsb pdb:7NJB|rcsb pdb:7NK3|rcsb pdb:7NK5|rcsb pdb:7NLA|rcsb pdb:7NLE|rcsb pdb:7NM1|rcsb pdb:7NM3|rcsb pdb:7NM9|rcsb pdb:7NQP|rcsb pdb:7NR7|rcsb pdb:7NRK|rcsb pdb:7NRL|rcsb pdb:7NSV|rcsb pdb:7NV4|rcsb pdb:7NVI|rcsb pdb:7NWS|rcsb pdb:7NXS|rcsb pdb:7NXT|rcsb pdb:7NXW|rcsb pdb:7NXY|rcsb pdb:7NY4|rcsb pdb:7NYE|rcsb pdb:7NYF|rcsb pdb:7NYG|rcsb pdb:7NZ6|rcsb pdb:7NZG|rcsb pdb:7NZK|reactome:R-HSA-6804114|reactome:R-HSA-75035|reactome:R-HSA-9614399|refseq:NP_006133.1|dip:DIP-29861N	-	crc64:8E71278ED6D3A912	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Uh6OsQDXtmnLKMAEZHl/NTKCEYY559292	rogid:HI+I1sXZRxVaRy9nzl3O0HmaSSE9606	intact-crc:75A9B3ED8EDEC621|rigid:tQVJ4k2Zv3BGIQUdO+iwOfZEkx8	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q03393	uniprotkb:P32502	intact:EBI-712344|ensembl:ENSP00000280362|uniprotkb:Q8WVG8|uniprotkb:B0YJ87	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:ptps_human(display_long)|uniprotkb:PTS(gene name)|psi-mi:PTS(display_short)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550800|imex:IM-24995-3271	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000308.1|ensembl:ENSG00000150787(gene)|ensembl:ENST00000280362(transcript)|go:"GO:0003874"(6-pyruvoyltetrahydropterin synthase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006520"(cellular amino acid metabolic process)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0007417"(central nervous system development)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR007115(6-pyruvoyl tetrahydropterin synthase-related)|interpro:IPR022469|interpro:IPR022470|interpro:IPR038418|rcsb pdb:3I2B|reactome:R-HSA-1474151	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731	-	-	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Qa3bMpzyvRxrvDq9dZUSQlfbpeg9606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:3896153CB7FD9F63|rigid:yR/xKlV7hNDD/Q9EM8NqkgdEspw	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P38340	uniprotkb:Q03393	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-712344|ensembl:ENSP00000280362|uniprotkb:Q8WVG8|uniprotkb:B0YJ87	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:ptps_human(display_long)|uniprotkb:PTS(gene name)|psi-mi:PTS(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550796|imex:IM-24995-3270	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F	refseq:NP_000308.1|ensembl:ENSG00000150787(gene)|ensembl:ENST00000280362(transcript)|go:"GO:0003874"(6-pyruvoyltetrahydropterin synthase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006520"(cellular amino acid metabolic process)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0007417"(central nervous system development)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR007115(6-pyruvoyl tetrahydropterin synthase-related)|interpro:IPR022469|interpro:IPR022470|interpro:IPR038418|rcsb pdb:3I2B|reactome:R-HSA-1474151	-	crc64:66699F37B0013088	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:Qa3bMpzyvRxrvDq9dZUSQlfbpeg9606	intact-crc:3487065A195744F9|rigid:/B45h0c5qBVDxEyJmefaim2Nfjw	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:G5E962	uniprotkb:Q03654	intact:EBI-11525615|ensembl:ENSP00000328177	intact:EBI-476|uniprotkb:Q6B1D8|ensemblfungi:YMR213W|uniprotkb:D6W038	psi-mi:g5e962_human(display_long)|uniprotkb:hCG_1644200(orf name)|uniprotkb:MAGEA11(gene name)|psi-mi:MAGEA11(display_short)	psi-mi:cef1_yeast(display_long)|uniprotkb:CEF1(gene name)|psi-mi:CEF1(display_short)|uniprotkb:YMR213W(locus name)|uniprotkb:YM8261.07(orf name)|uniprotkb:NTC85(gene name synonym)|uniprotkb:PRP nineteen-associated complex protein 85(gene name synonym)|uniprotkb:PRP19-associated complex protein 85(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550804|imex:IM-24995-3272	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001011544.1|ensembl:ENSG00000185247(gene)|ensembl:ENST00000333104(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016604"(nuclear body)|interpro:IPR002190(MAGE protein)|interpro:IPR021072|interpro:IPR030099|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899	refseq:NP_013940.1|sgd:S000004826|ensemblfungi:YMR213W(gene)|ensemblfungi:YMR213W_mRNA(transcript)|go:"GO:0000350"(generation of catalytic spliceosome for second transesterification step)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000974"(Prp19 complex)|go:"GO:0003677"(DNA binding)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017930|interpro:IPR021786|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|rcsb pdb:7DCO|dip:DIP-1113N|mint:Q03654	-	-	crc64:A4C417A8B330EA9C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:sVB0aA6yibWUx/d2SE+pwpKKgtI9606	rogid:AsbV7RtNk+8mCzLk2wZYqbULOFg559292	intact-crc:51E679FF3482BE85|rigid:L+RpFPw6IWhOHFNjUFked8U1UUM	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O94993	uniprotkb:Q04307	intact:EBI-742973|ensembl:ENSP00000265007|uniprotkb:O94995|uniprotkb:Q8IYX6	intact:EBI-15858|uniprotkb:Q2VQW5|ensemblfungi:YDR045C|uniprotkb:D6VS33	psi-mi:sox30_human(display_long)|uniprotkb:SOX30(gene name)|psi-mi:SOX30(display_short)	psi-mi:rpc10_yeast(display_long)|uniprotkb:RPC11(gene name)|psi-mi:RPC11(display_short)|uniprotkb:YDR045C(locus name)|uniprotkb:YD9609.01C(orf name)|uniprotkb:RNA polymerase III subunit C11(gene name synonym)|uniprotkb:DNA-directed RNA polymerases III 12.5 kDa polypeptide(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550844|imex:IM-24995-3282	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:7JJK|refseq:NP_008948.1|refseq:NP_848511.1|ensembl:ENSG00000039600(gene)|ensembl:ENST00000265007(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007286"(spermatid development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0010369"(chromocenter)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0031960"(response to corticosteroid)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0120211"(proacrosomal vesicle fusion)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR036910|refseq:NP_001295094.1	ensemblfungi:YDR045C(gene)|refseq:NP_010330.1|sgd:S000002452|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006386"(termination of RNA polymerase III transcription)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042779"(tRNA 3'-trailer cleavage)|go:"GO:0042797"(tRNA transcription by RNA polymerase III)|interpro:IPR001222(Zinc finger, TFIIS-type)|interpro:IPR001529(DNA-directed RNA polymerase, M/15 kDa subunit)|interpro:IPR012164(DNA-directed RNA polymerase, subunit C11/M/9)|interpro:IPR019761|interpro:IPR034014|rcsb pdb:3QT1|ensemblfungi:YDR045C_mRNA(transcript)|rcsb pdb:5FJ8|rcsb pdb:5FJ9|rcsb pdb:5FJA|rcsb pdb:6CNB|rcsb pdb:6CNC|rcsb pdb:6CND|rcsb pdb:6CNF|rcsb pdb:6EU0|rcsb pdb:6EU2|rcsb pdb:6EU3|rcsb pdb:6F40|rcsb pdb:6F41|rcsb pdb:6F42|rcsb pdb:6F44|rcsb pdb:6TUT|reactome:R-SCE-76061|reactome:R-SCE-76066|rcsb pdb:6EU1|dip:DIP-887N|mint:Q04307	-	-	crc64:E4AA802EC9F92230	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:AriyqffK8zuvudW4qjQ9SvnA0Vg9606	rogid:G2fIQbptabHIUI224iPtTJF+dIs559292	intact-crc:B78D983AABF76FDD|rigid:xzx0s+fgkwgoNfQYRTGCdsfHnvo	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q04307	uniprotkb:P32321	intact:EBI-15858|uniprotkb:Q2VQW5|ensemblfungi:YDR045C|uniprotkb:D6VS33	intact:EBI-739870|uniprotkb:Q9BVD8|uniprotkb:B2R836|uniprotkb:Q5M7Z8|uniprotkb:D3DP49|uniprotkb:D3DP50|ensembl:ENSP00000398194|ensembl:ENSP00000424017	psi-mi:rpc10_yeast(display_long)|uniprotkb:RPC11(gene name)|psi-mi:RPC11(display_short)|uniprotkb:YDR045C(locus name)|uniprotkb:YD9609.01C(orf name)|uniprotkb:RNA polymerase III subunit C11(gene name synonym)|uniprotkb:DNA-directed RNA polymerases III 12.5 kDa polypeptide(gene name synonym)	psi-mi:dctd_human(display_long)|uniprotkb:DCTD(gene name)|psi-mi:DCTD(display_short)|uniprotkb:dCMP deaminase(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550840|imex:IM-24995-3281	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YDR045C(gene)|refseq:NP_010330.1|sgd:S000002452|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006386"(termination of RNA polymerase III transcription)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042779"(tRNA 3'-trailer cleavage)|go:"GO:0042797"(tRNA transcription by RNA polymerase III)|interpro:IPR001222(Zinc finger, TFIIS-type)|interpro:IPR001529(DNA-directed RNA polymerase, M/15 kDa subunit)|interpro:IPR012164(DNA-directed RNA polymerase, subunit C11/M/9)|interpro:IPR019761|interpro:IPR034014|rcsb pdb:3QT1|ensemblfungi:YDR045C_mRNA(transcript)|rcsb pdb:5FJ8|rcsb pdb:5FJ9|rcsb pdb:5FJA|rcsb pdb:6CNB|rcsb pdb:6CNC|rcsb pdb:6CND|rcsb pdb:6CNF|rcsb pdb:6EU0|rcsb pdb:6EU2|rcsb pdb:6EU3|rcsb pdb:6F40|rcsb pdb:6F41|rcsb pdb:6F42|rcsb pdb:6F44|rcsb pdb:6TUT|reactome:R-SCE-76061|reactome:R-SCE-76066|rcsb pdb:6EU1|dip:DIP-887N|mint:Q04307	refseq:NP_001012750.1|refseq:NP_001912.2|ensembl:ENSG00000129187(gene)|ensembl:ENST00000438320(transcript)|ensembl:ENST00000510370(transcript)|go:"GO:0004132"(dCMP deaminase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006220"(pyrimidine nucleotide metabolic process)|go:"GO:0006226"(dUMP biosynthetic process)|go:"GO:0006231"(dTMP biosynthetic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR002125(CMP/dCMP deaminase, zinc-binding)|interpro:IPR015517(Cytidine deaminase)|interpro:IPR016192(APOBEC/CMP deaminase, zinc-binding)|interpro:IPR016193(Cytidine deaminase-like)|interpro:IPR016473(dCMP deaminase)|interpro:IPR035105|mint:P32321|rcsb pdb:2W4L|reactome:R-HSA-499943|refseq:XP_005262836.1|refseq:XP_005262837.1|refseq:XP_011529976.1|refseq:XP_016863305.1|refseq:XP_016863306.1|refseq:XP_016863307.1|refseq:XP_016863308.1|refseq:XP_016863309.1|refseq:XP_016863310.1|refseq:XP_016863311.1	-	crc64:E4AA802EC9F92230	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:G2fIQbptabHIUI224iPtTJF+dIs559292	rogid:lU3gEi7XdIJbuPlMkForbVKEOyY9606	intact-crc:A02183E7E2BE586E|rigid:C+v6NwAw2T/AZMrpbmOP+ZTq6cI	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q7Z6G3-2	uniprotkb:Q04307	intact:EBI-10172876|ensembl:ENSP00000457354|intact:EBI-14062040	intact:EBI-15858|uniprotkb:Q2VQW5|ensemblfungi:YDR045C|uniprotkb:D6VS33	psi-mi:q7z6g3-2(display_long)|uniprotkb:EFCBP2(gene name synonym)|uniprotkb:Neuronal calcium-binding protein 2(gene name synonym)|uniprotkb:Synaptotagmin-interacting protein 2(gene name synonym)|uniprotkb:NECAB2(gene name)|psi-mi:NECAB2(display_short)	psi-mi:rpc10_yeast(display_long)|uniprotkb:RPC11(gene name)|psi-mi:RPC11(display_short)|uniprotkb:YDR045C(locus name)|uniprotkb:YD9609.01C(orf name)|uniprotkb:RNA polymerase III subunit C11(gene name synonym)|uniprotkb:DNA-directed RNA polymerases III 12.5 kDa polypeptide(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550836|imex:IM-24995-3280	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000103154(gene)|ensembl:ENST00000565691(transcript)|uniprotkb:Q7Z6G3-2(isoform-parent)|intact:EBI-950070(isoform-parent)	ensemblfungi:YDR045C(gene)|refseq:NP_010330.1|sgd:S000002452|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006386"(termination of RNA polymerase III transcription)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042779"(tRNA 3'-trailer cleavage)|go:"GO:0042797"(tRNA transcription by RNA polymerase III)|interpro:IPR001222(Zinc finger, TFIIS-type)|interpro:IPR001529(DNA-directed RNA polymerase, M/15 kDa subunit)|interpro:IPR012164(DNA-directed RNA polymerase, subunit C11/M/9)|interpro:IPR019761|interpro:IPR034014|rcsb pdb:3QT1|ensemblfungi:YDR045C_mRNA(transcript)|rcsb pdb:5FJ8|rcsb pdb:5FJ9|rcsb pdb:5FJA|rcsb pdb:6CNB|rcsb pdb:6CNC|rcsb pdb:6CND|rcsb pdb:6CNF|rcsb pdb:6EU0|rcsb pdb:6EU2|rcsb pdb:6EU3|rcsb pdb:6F40|rcsb pdb:6F41|rcsb pdb:6F42|rcsb pdb:6F44|rcsb pdb:6TUT|reactome:R-SCE-76061|reactome:R-SCE-76066|rcsb pdb:6EU1|dip:DIP-887N|mint:Q04307	-	-	crc64:E4AA802EC9F92230	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:4S7oIx6h+mKzV3EPxqcfMNqaNko9606	rogid:G2fIQbptabHIUI224iPtTJF+dIs559292	intact-crc:8411AFF4C2C5C07C|rigid:Um+HMOYZtBTpcWmb37no39hEDIw	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P43356	uniprotkb:Q03981	intact:EBI-5650739|uniprotkb:A8K328|uniprotkb:Q32NC6|ensembl:ENSP00000333487|ensembl:ENSP00000359316|ensembl:ENSP00000469919|ensembl:ENSP00000470872|ensembl:ENSP00000480491|ensembl:ENSP00000480738|ensembl:ENSP00000484290|ensembl:ENSP00000485391|ensembl:ENSP00000485541|ensembl:ENSP00000507594|ensembl:ENSP00000507899	intact:EBI-33535|uniprotkb:D6VSG1|ensemblfungi:YDR179C	psi-mi:maga2_human(display_long)|uniprotkb:MAGEA2(gene name)|psi-mi:MAGEA2(display_short)|uniprotkb:MAGEA2B(gene name)|psi-mi:MAGEA2B(display_short)|uniprotkb:MAGE2(gene name synonym)|uniprotkb:MAGEA2A(gene name synonym)|uniprotkb:MAGE2(gene name synonym)|uniprotkb:MAGEA2(gene name synonym)|uniprotkb:Cancer/testis antigen 1.2(gene name synonym)|uniprotkb:MAGE-2 antigen(gene name synonym)	psi-mi:csn9_yeast(display_long)|uniprotkb:CSN9(gene name)|psi-mi:CSN9(display_short)|uniprotkb:YDR179C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550820|imex:IM-24995-3276	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001269430.1|refseq:NP_001269431.1|refseq:NP_001269433.1|refseq:NP_001269434.1|refseq:NP_001308329.1|refseq:NP_001308330.1|refseq:NP_001308331.1|refseq:NP_001308332.1|refseq:NP_001308333.1|refseq:NP_005352.1|refseq:NP_705692.1|refseq:NP_786884.1|refseq:NP_786885.1|dip:DIP-61231N|refseq:XP_016884895.1|refseq:XP_016885008.1|ensembl:ENSG00000183305(gene)|ensembl:ENSG00000268606(gene)|ensembl:ENST00000331220(transcript)|ensembl:ENST00000370293(transcript)|ensembl:ENST00000595583(transcript)|ensembl:ENST00000598543(transcript)|ensembl:ENST00000611557(transcript)|ensembl:ENST00000611674(transcript)|ensembl:ENST00000620710(transcript)|ensembl:ENST00000623438(transcript)|ensembl:ENST00000623806(transcript)|ensembl:ENST00000682532(transcript)|ensembl:ENST00000684311(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0016605"(PML body)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0033234"(negative regulation of protein sumoylation)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0044257"(cellular protein catabolic process)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0072331"(signal transduction by p53 class mediator)|go:"GO:0090398"(cellular senescence)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901984"(negative regulation of protein acetylation)|interpro:IPR002190(MAGE protein)|interpro:IPR021072|interpro:IPR030103|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899	refseq:NP_010464.1|sgd:S000002586|mint:Q03981|dip:DIP-1580N|ensemblfungi:YDR179C(gene)|ensemblfungi:YDR179C_mRNA(transcript)|go:"GO:0000338"(protein deneddylation)|go:"GO:0000754"(adaptation of signaling pathway by response to pheromone involved in conjugation with cellular fusion)|go:"GO:0005737"(cytoplasm)|go:"GO:0008180"(COP9 signalosome)|interpro:IPR016806(COP9 signalosome complex, subunit 9)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:aYv4+irEk9vGE2f3yZQR8hCQGec9606	rogid:DHoL1YAXDCBQU4RcLn9kg4T00V0559292	intact-crc:860C2641D9E87883|rigid:DwZKi1PtUD53+blnRvAz8zMYZxk	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O43765	uniprotkb:Q04201	intact:EBI-347996|ensembl:ENSP00000221566|ensembl:ENSP00000503397|ensembl:ENSP00000504495|uniprotkb:Q9BTZ9|intact:EBI-1045243|uniprotkb:Q6FIA9|uniprotkb:D6W610	intact:EBI-27928|uniprotkb:D6W0I3|ensemblfungi:YML101C	psi-mi:sgta_human(display_long)|uniprotkb:SGTA(gene name)|psi-mi:SGTA(display_short)|uniprotkb:SGT(gene name synonym)|uniprotkb:Alpha-SGT(gene name synonym)|uniprotkb:Vpu-binding protein(gene name synonym)|uniprotkb:SGT1(gene name synonym)	psi-mi:cue4_yeast(display_long)|uniprotkb:YML101C(locus name)|uniprotkb:Coupling of ubiquitin conjugation to ER degradation protein 4(gene name synonym)|uniprotkb:CUE4(gene name)|psi-mi:CUE4(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550828|imex:IM-24995-3278	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:4CPG|rcsb pdb:4GOD|rcsb pdb:4GOE|rcsb pdb:4GOF|reactome:R-HSA-9609523|rcsb pdb:2VYI|ensembl:ENSG00000104969(gene)|ensembl:ENST00000221566(transcript)|ensembl:ENST00000676943(transcript)|ensembl:ENST00000677149(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072380"(TRC complex)|go:"GO:0098850"(extrinsic component of synaptic vesicle membrane)|go:"GO:1903070"(negative regulation of ER-associated ubiquitin-dependent protein catabolic process)|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)|go:"GO:1903646"(positive regulation of chaperone-mediated protein folding)|go:"GO:1904288"(BAT3 complex binding)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR032374|mint:O43765|refseq:XP_011526480.1|refseq:NP_003012.1	refseq:NP_013607.1|sgd:S000004568|dip:DIP-4525N|mint:Q04201|ensemblfungi:YML101C(gene)|ensemblfungi:YML101C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR003892(Ubiquitin system component Cue)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:r/Cyj4UJk/cS8QdrbjhTZMPCigI9606	rogid:NMBJHZbX4/gU01fk4evPDXm/M6w559292	intact-crc:849F8B007BD0EDDD|rigid:lkUYU9YQdUZyJS+qFXE4avLypoQ	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q04110	uniprotkb:P63279	intact:EBI-37150|uniprotkb:D6VT71|ensemblfungi:YDR446W	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	psi-mi:ecm11_yeast(display_long)|uniprotkb:ECM11(gene name)|psi-mi:ECM11(display_short)|uniprotkb:YDR446W(locus name)|uniprotkb:D9461.31(orf name)|uniprotkb:Extracellular mutant protein 11(gene name synonym)	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550824|imex:IM-24995-3277	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002854|refseq:NP_010734.1|dip:DIP-2060N|ensemblfungi:YDR446W(gene)|ensemblfungi:YDR446W_mRNA(transcript)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0005634"(nucleus)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0070193"(synaptonemal complex organization)|go:"GO:0071555"(cell wall organization)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|interpro:IPR029178	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N	-	crc64:CB6890F4EE069232	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:F5ueMuYv+ymWlt2junW3o49OB/g559292	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	intact-crc:3BA8243BE762C3F8|rigid:PbVxpQjOy6uwNdh04tE2X2XI63A	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q04264	uniprotkb:O95198	intact:EBI-13077|uniprotkb:Q04780|uniprotkb:D6VZQ0|ensemblfungi:YMR076C	intact:EBI-746999|uniprotkb:B2RD18|uniprotkb:Q8N484|uniprotkb:Q8TBH5|uniprotkb:A6NCM7|uniprotkb:B4DFH7|uniprotkb:F5H6M3|ensembl:ENSP00000226725	psi-mi:pds5_yeast(display_long)|uniprotkb:PDS5(gene name)|psi-mi:PDS5(display_short)|uniprotkb:YMR076C(locus name)|uniprotkb:YM9916.15C(orf name)|uniprotkb:YM9582.01C(orf name)|uniprotkb:Precocious dissociation of sisters protein 5(gene name synonym)	psi-mi:klhl2_human(display_long)|uniprotkb:Actin-binding protein Mayven(gene name synonym)|uniprotkb:KLHL2(gene name)|psi-mi:KLHL2(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550832|imex:IM-24995-3279	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013793.1|sgd:S000004681|mint:Q04264|dip:DIP-6799N|ensemblfungi:YMR076C(gene)|ensemblfungi:YMR076C_mRNA(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0035808"(meiotic recombination initiation complex)|go:"GO:0042138"(meiotic DNA double-strand break formation)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0140588"(chromatin looping)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR032682|interpro:IPR039776|rcsb pdb:5FRP|rcsb pdb:5FRR|rcsb pdb:5FRS|reactome:R-SCE-2468052|reactome:R-SCE-2500257	refseq:NP_001154993.1|refseq:NP_001154994.1|refseq:NP_009177.3|refseq:NP_001317952.1|refseq:NP_001317953.1|refseq:XP_016863165.1|ensembl:ENSG00000109466(gene)|ensembl:ENST00000226725(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030027"(lamellipodium)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR017096(Kelch-like protein, gigaxonin)|interpro:IPR044072|mint:O95198|rcsb pdb:2XN4|rcsb pdb:4CHB|reactome:R-HSA-8951664|reactome:R-HSA-983168|go:"GO:0042802"(identical protein binding)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:JtsuFYTdfc1TRvCvtjuJ8AAHCoU559292	rogid:tFegR2lJZccRqs4qUjdT3PNjNnk9606	intact-crc:617B9FE3E222A163|rigid:eApCGZd/gWtKLU55u76zojhWfPI	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q04712	uniprotkb:O95273	intact:EBI-27790|uniprotkb:D6VZD2|ensemblfungi:YML043C	intact:EBI-748961|uniprotkb:A8K3Q0|uniprotkb:A8K3U2|uniprotkb:Q6ZQN9|uniprotkb:Q7Z519|uniprotkb:Q8NBS7|uniprotkb:Q8NBY2|uniprotkb:Q9NS19|uniprotkb:Q9NYH3|uniprotkb:Q9UHX9|ensembl:ENSP00000300213	psi-mi:rrn11_yeast(display_long)|uniprotkb:YM9827.09C(orf name)|uniprotkb:YML043C(locus name)|uniprotkb:RRN11(gene name)|psi-mi:RRN11(display_short)	psi-mi:ccdb1_human(display_long)|uniprotkb:Grap2 and cyclin-D-interacting protein(gene name synonym)|uniprotkb:Human homolog of Maid(gene name synonym)|uniprotkb:CCNDBP1(gene name)|psi-mi:CCNDBP1(display_short)|uniprotkb:DIP1(gene name synonym)|uniprotkb:GCIP(gene name synonym)|uniprotkb:HHM(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550868|imex:IM-24995-3288	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013669.1|sgd:S000004507|dip:DIP-4542N|mint:Q04712|ensemblfungi:YML043C(gene)|ensemblfungi:YML043C_mRNA(transcript)|go:"GO:0001164"(RNA polymerase I core promoter sequence-specific DNA binding)|go:"GO:0001181"(RNA polymerase I general transcription initiation factor activity)|go:"GO:0005730"(nucleolus)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0042790"(nucleolar large rRNA transcription by RNA polymerase I)|go:"GO:0070860"(RNA polymerase I core factor complex)|interpro:IPR007224(RNA polymerase I specific initiation factor)|interpro:IPR016850(Core factor complex, Rrn11 component)|rcsb pdb:5N5Y|rcsb pdb:5N5Z|rcsb pdb:5N60|rcsb pdb:5N61|rcsb pdb:5O7X|rcsb pdb:5OA1|rcsb pdb:5W5Y|rcsb pdb:5W64|rcsb pdb:5W65|rcsb pdb:5W66|rcsb pdb:6RQH|rcsb pdb:6RQL|rcsb pdb:6RRD|rcsb pdb:6RUI|rcsb pdb:6RUO|rcsb pdb:6RWE|rcsb pdb:6TPS	refseq:NP_036274.3|ensembl:ENSG00000166946(gene)|ensembl:ENST00000300213(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0016604"(nuclear body)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR026907|mint:O95273|rcsb pdb:3AY5	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:HeXVovHQGBfbg6FbSkFO9/T64hE559292	rogid:Vi9aoFc+Mov6P3X6KGmsTxXqxvM9606	intact-crc:67BFF79F9467E0CC|rigid:kDcumX4pkJwS3XoIcxA5QZJa6JE	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q04638	uniprotkb:Q8N5R6	intact:EBI-27858|uniprotkb:D6VZA5|ensemblfungi:YML068W	intact:EBI-740841|intact:EBI-953781|uniprotkb:B3KQ49|uniprotkb:A8K3U4|uniprotkb:A8MPQ6|uniprotkb:A8MV61|uniprotkb:A8MVU9|uniprotkb:Q9H5Q6|uniprotkb:Q8TAX6|intact:EBI-2320546|intact:EBI-11522976	psi-mi:itt1_yeast(display_long)|uniprotkb:ITT1(gene name)|psi-mi:ITT1(display_short)|uniprotkb:YML068W(locus name)	psi-mi:ccd33_human(display_long)|uniprotkb:CCDC33(gene name)|psi-mi:CCDC33(display_short)|uniprotkb:Cancer/testis antigen 61(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550864|imex:IM-24995-3287	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013643.1|sgd:S000004533|dip:DIP-1952N|mint:Q04638|ensemblfungi:YML068W(gene)|ensemblfungi:YML068W_mRNA(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005737"(cytoplasm)|go:"GO:0006449"(regulation of translational termination)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002867(Zinc finger, C6HC-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR031127|interpro:IPR044066	refseq:NP_079331.3|interpro:IPR000008(C2 calcium-dependent membrane targeting)|go:"GO:0005777"(peroxisome)|refseq:NP_001274110.1|refseq:NP_877592.2|mint:Q8N5R6|interpro:IPR035892|interpro:IPR039889	-	crc64:F481372B742AF63D	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2021/11/30	rogid:gPNBZ7jeo4QD4M26MqrTGBZqVZY559292	rogid:eEIn7pQyfdHWx8TeLJpYy0i/gww9606	intact-crc:CD96D9977A108EE5|rigid:Rv1qP9yRgGM74WMA2bnWZQ0Rev4	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q04323	uniprotkb:P40325	intact:EBI-1058647|ensembl:ENSP00000303991|uniprotkb:Q9BV93|uniprotkb:Q9BVV5|intact:EBI-1993649	intact:EBI-23614|uniprotkb:D6VV46|ensemblfungi:YGR268C	psi-mi:ubxn1_human(display_long)|uniprotkb:UBXN1(gene name)|psi-mi:UBXN1(display_short)|uniprotkb:SAKS1(gene name synonym)|uniprotkb:SAPK substrate protein 1(gene name synonym)|uniprotkb:UBA/UBX 33.3 kDa protein(gene name synonym)	psi-mi:hua1_yeast(display_long)|uniprotkb:HUA1(gene name)|psi-mi:HUA1(display_short)|uniprotkb:YGR268C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550848|imex:IM-24995-3283	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000162191(gene)|ensembl:ENST00000301935(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0030425"(dendrite)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0036435"(K48-linked polyubiquitin modification-dependent protein binding)|refseq:NP_001273006.1|refseq:NP_001273007.1|refseq:NP_056937.2|go:"GO:0043025"(neuronal cell body)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0051117"(ATPase binding)|go:"GO:0071796"(K6-linked polyubiquitin modification-dependent protein binding)|go:"GO:1903094"(negative regulation of protein K48-linked deubiquitination)|go:"GO:1904293"(negative regulation of ERAD pathway)|go:"GO:1904855"(proteasome regulatory particle binding)|go:"GO:2000157"(negative regulation of ubiquitin-specific protease activity)|interpro:IPR001012(UBX)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR029071|interpro:IPR041923|reactome:R-HSA-532668|reactome:R-HSA-5693565|go:"GO:0043130"(ubiquitin binding)|refseq:XP_005274090.1|refseq:XP_016873363.1|dip:DIP-29467N	sgd:S000003500|refseq:NP_011784.3|dip:DIP-1987N|ensemblfungi:YGR268C(gene)|ensemblfungi:YGR268C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|interpro:IPR038910	-	crc64:E4E0C8BBAC93F2BB	crc64:78029FD484168793	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:KdHMRM9FSd6VT6MvJTxzdjARlRw9606	rogid:xliNG9XUWbYRd0Nbu+xzCgxNrAs559292	intact-crc:E7CA157283A03360|rigid:Uta6w9dHHb/gnO/HqSVuBGJTaqE	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:A2A369	uniprotkb:Q04461	intact:EBI-11530808|ensembl:ENSP00000371766	intact:EBI-27209|uniprotkb:D6VZT4|ensemblfungi:YMR111C	psi-mi:a2a369_human(display_long)|uniprotkb:DOCK8(gene name)|psi-mi:DOCK8(display_short)	psi-mi:euc1_yeast(display_long)|uniprotkb:EUC1(gene name)|psi-mi:EUC1(display_short)|uniprotkb:Enriches ubiquitin on chromatin protein 1(gene name synonym)|uniprotkb:YM9718.10C(orf name)|uniprotkb:YMR111C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550856|imex:IM-24995-3285	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000107099(gene)|ensembl:ENST00000382329(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0007264"(small GTPase mediated signal transduction)|interpro:IPR010703(Dedicator of cytokinesis)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026791|interpro:IPR027007|interpro:IPR027357|interpro:IPR035892|interpro:IPR043161|interpro:IPR043162	refseq:NP_013829.1|sgd:S000004717|dip:DIP-2716N|ensemblfungi:YMR111C(gene)|ensemblfungi:YMR111C_mRNA(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0034629"|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0060963"(positive regulation of ribosomal protein gene transcription by RNA polymerase II)|interpro:IPR022210	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:Sa5ulmmVxrpxZ+GAhN64RAHXYdk9606	rogid:Wpg0ztvlnbV6BXPwJKqWehavPGA559292	intact-crc:B61E25CAC8E096BD|rigid:BpcaaJVBWTylkwcmkR9N9YwL7EQ	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P40325	uniprotkb:Q04323-2	intact:EBI-23614|uniprotkb:D6VV46|ensemblfungi:YGR268C	intact:EBI-11530712|ensembl:ENSP00000294119	psi-mi:hua1_yeast(display_long)|uniprotkb:HUA1(gene name)|psi-mi:HUA1(display_short)|uniprotkb:YGR268C(locus name)	psi-mi:q04323-2(display_long)|uniprotkb:UBXN1(gene name)|psi-mi:UBXN1(display_short)|uniprotkb:SAKS1(gene name synonym)|uniprotkb:SAPK substrate protein 1(gene name synonym)|uniprotkb:UBA/UBX 33.3 kDa protein(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550852|imex:IM-24995-3284	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003500|refseq:NP_011784.3|dip:DIP-1987N|ensemblfungi:YGR268C(gene)|ensemblfungi:YGR268C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|interpro:IPR038910	ensembl:ENSG00000162191(gene)|ensembl:ENST00000294119(transcript)|intact:EBI-1058647(isoform-parent)|uniprotkb:Q04323-2(isoform-parent)	-	crc64:78029FD484168793	isoform-comment:No experimental confirmation available.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:xliNG9XUWbYRd0Nbu+xzCgxNrAs559292	rogid:3DD93eyg5bSqmm3twiOfff+2Bps9606	intact-crc:113659C405BABA09|rigid:LciiCbDcklBbHVh0PdJE3y0ERzY	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q04603	uniprotkb:Q01658	intact:EBI-29938|uniprotkb:D6VSA7|ensemblfungi:YDR121W	intact:EBI-750300|ensembl:ENSP00000359290|ensembl:ENSP00000359295	psi-mi:dpb4_yeast(display_long)|uniprotkb:DPB4(gene name)|psi-mi:DPB4(display_short)|uniprotkb:DNA polymerase II subunit D(gene name synonym)|uniprotkb:YDR121W(locus name)	psi-mi:nc2b_human(display_long)|uniprotkb:Down-regulator of transcription 1(gene name synonym)|uniprotkb:TATA-binding protein-associated phosphoprotein(gene name synonym)|uniprotkb:Negative cofactor 2-beta(gene name synonym)|uniprotkb:DR1(gene name)|psi-mi:DR1(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550860|imex:IM-24995-3286	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002528|refseq:NP_010406.3|dip:DIP-4621N|mint:Q04603|ensemblfungi:YDR121W(gene)|ensemblfungi:YDR121W_mRNA(transcript)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006272"(leading strand elongation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008622"(epsilon DNA polymerase complex)|go:"GO:0008623"(CHRAC)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0042276"(error-prone translesion synthesis)|go:"GO:0042766"(nucleosome mobilization)|go:"GO:0043044"|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0070868"(obsolete heterochromatin organization involved in chromatin silencing)|go:"GO:0090305"(nucleic acid phosphodiester bond hydrolysis)|interpro:IPR009072(Histone-fold)|rcsb pdb:6WJV|reactome:R-SCE-5656169|reactome:R-SCE-6782135|reactome:R-SCE-68952|reactome:R-SCE-68962	refseq:NP_001929.1|ensembl:ENSG00000117505(gene)|ensembl:ENST00000370267(transcript)|ensembl:ENST00000370272(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0017054"(negative cofactor 2 complex)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR003958(Transcription factor CBF/NF-Y/archaeal histone)|interpro:IPR009072(Histone-fold)|interpro:IPR042225|mint:Q01658|rcsb pdb:1JFI|reactome:R-HSA-3214847	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:vEA21+6hLP2O4eSSuKA49lbi0E0559292	rogid:lrcYCVWbIkFU01ETSmd3cX++jLw9606	intact-crc:164D297CACC15DE7|rigid:0oW2EWGQH4fLj7PWG+Nqd7E+B4U	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O43765	uniprotkb:Q05899	intact:EBI-347996|ensembl:ENSP00000221566|ensembl:ENSP00000503397|ensembl:ENSP00000504495|uniprotkb:Q9BTZ9|intact:EBI-1045243|uniprotkb:Q6FIA9|uniprotkb:D6W610	intact:EBI-33462|uniprotkb:D6VYU1|ensemblfungi:YLR297W	psi-mi:sgta_human(display_long)|uniprotkb:SGTA(gene name)|psi-mi:SGTA(display_short)|uniprotkb:SGT(gene name synonym)|uniprotkb:Alpha-SGT(gene name synonym)|uniprotkb:Vpu-binding protein(gene name synonym)|uniprotkb:SGT1(gene name synonym)	psi-mi:yl297_yeast(display_long)|uniprotkb:YLR297W(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550884|imex:IM-24995-3292	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:4CPG|rcsb pdb:4GOD|rcsb pdb:4GOE|rcsb pdb:4GOF|reactome:R-HSA-9609523|rcsb pdb:2VYI|ensembl:ENSG00000104969(gene)|ensembl:ENST00000221566(transcript)|ensembl:ENST00000676943(transcript)|ensembl:ENST00000677149(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072380"(TRC complex)|go:"GO:0098850"(extrinsic component of synaptic vesicle membrane)|go:"GO:1903070"(negative regulation of ER-associated ubiquitin-dependent protein catabolic process)|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)|go:"GO:1903646"(positive regulation of chaperone-mediated protein folding)|go:"GO:1904288"(BAT3 complex binding)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR032374|mint:O43765|refseq:XP_011526480.1|refseq:NP_003012.1	sgd:S000004288|refseq:NP_013400.1|dip:DIP-4684N|ensemblfungi:YLR297W(gene)|ensemblfungi:YLR297W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016021"(integral component of membrane)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:r/Cyj4UJk/cS8QdrbjhTZMPCigI9606	rogid:5NnJTt1UJw0+xxbJS5roF36sLGI559292	intact-crc:0BD340E0606A99C7|rigid:0yAmIuTTO1UefLVVsZaLO9S1Hs0	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O60684	uniprotkb:Q04978	intact:EBI-359923|uniprotkb:Q5VVU3|uniprotkb:B2RDC7|ensembl:ENSP00000362728|uniprotkb:D3DPP5	intact:EBI-27823|uniprotkb:D6VZC2|ensemblfungi:YML053C	psi-mi:ima7_human(display_long)|uniprotkb:KPNA6(gene name)|psi-mi:KPNA6(display_short)|uniprotkb:IPOA7(gene name synonym)|uniprotkb:Karyopherin subunit alpha-6(gene name synonym)	psi-mi:ymf3_yeast(display_long)|uniprotkb:YM9958.09C(orf name)|uniprotkb:YML053C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550872|imex:IM-24995-3289	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_036448.1|ensembl:ENSG00000025800(gene)|ensembl:ENST00000373625(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0016020"(membrane)|go:"GO:0019079"(viral genome replication)|go:"GO:0030682"(mitigation of host defenses by symbiont)|go:"GO:0043657"(host cell)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060135"(maternal process involved in female pregnancy)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0075506"(entry of viral genome into host nucleus through nuclear pore complex via importin)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:1903902"(positive regulation of viral life cycle)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|mint:O60684|rcsb pdb:4UAD|dip:DIP-27609N	sgd:S000004517|refseq:NP_013659.1|dip:DIP-1950N|ensemblfungi:YML053C(gene)|ensemblfungi:YML053C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:3NsSIcE6BHIqYlvfGRolUKD/5uc9606	rogid:eYvLCLQP+e6HSEiAjDeWkJBUCTU559292	intact-crc:51EA057FDFB14080|rigid:GpHakCsqlndyZ6pH+os8y4W+2WU	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q05164	uniprotkb:O43791	intact:EBI-31733|uniprotkb:Q08294|uniprotkb:D6W1R6|ensemblfungi:YOL155C	intact:EBI-743549|uniprotkb:Q53HJ1|uniprotkb:B2R6S3|uniprotkb:D3DTW7|ensembl:ENSP00000240327|ensembl:ENSP00000377001|ensembl:ENSP00000420908|ensembl:ENSP00000424119|ensembl:ENSP00000425905|ensembl:ENSP00000426986|ensembl:ENSP00000499562	psi-mi:hpf1_yeast(display_long)|uniprotkb:HPF1(gene name)|psi-mi:HPF1(display_short)|uniprotkb:AOF1001(orf name)|uniprotkb:YOL155C(locus name)	psi-mi:spop_human(display_long)|uniprotkb:HIB homolog 1(gene name synonym)|uniprotkb:Roadkill homolog 1(gene name synonym)|uniprotkb:SPOP(gene name)|psi-mi:SPOP(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550876|imex:IM-24995-3290	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005515|refseq:NP_014487.1|interpro:IPR021031|mint:Q05164|ensemblfungi:YOL155C(gene)|ensemblfungi:YOL155C_mRNA(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0009277"(fungal-type cell wall)|go:"GO:0015926"(glucosidase activity)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0071944"(cell periphery)|reactome:R-SCE-983168	refseq:NP_001007227.1|refseq:NP_001007228.1|refseq:NP_001007229.1|refseq:NP_001007230.1|refseq:NP_001007231.1|refseq:NP_003554.1|refseq:XP_005257780.1|refseq:XP_005257781.1|ensembl:ENSG00000121067(gene)|ensembl:ENST00000347630(transcript)|ensembl:ENST00000393328(transcript)|ensembl:ENST00000503676(transcript)|ensembl:ENST00000504102(transcript)|ensembl:ENST00000509079(transcript)|ensembl:ENST00000514121(transcript)|ensembl:ENST00000665825(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0016607"(nuclear speck)|go:"GO:0030162"(regulation of proteolysis)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR034089|mint:O43791|rcsb pdb:2CR2|rcsb pdb:3HQH|rcsb pdb:3HQI|rcsb pdb:3HQL|rcsb pdb:3HQM|rcsb pdb:3HSV|rcsb pdb:3HTM|rcsb pdb:3HU6|rcsb pdb:3IVB|rcsb pdb:3IVQ|rcsb pdb:3IVV|rcsb pdb:4EOZ|rcsb pdb:4HS2|rcsb pdb:4J8Z|rcsb pdb:4O1V|rcsb pdb:6F8F|rcsb pdb:6F8G|rcsb pdb:6I41|rcsb pdb:6I5P|rcsb pdb:6I68|rcsb pdb:6I7A|rcsb pdb:7D3D|rcsb pdb:7LIN|rcsb pdb:7LIO|rcsb pdb:7LIP|rcsb pdb:7LIQ|reactome:R-HSA-5632684|go:"GO:0005634"(nucleus)|refseq:XP_016880693.1|dip:DIP-50517N	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:6bUWFxCsumvuNKLLVzCUfBbL1hA559292	rogid:PC9ofpvk14xwTnnqT590/YRnx/49606	intact-crc:12753257ABEEDB5E|rigid:LtppZUYycnOgqRhpbMJVkBufiRg	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q05164	uniprotkb:G5E962	intact:EBI-31733|uniprotkb:Q08294|uniprotkb:D6W1R6|ensemblfungi:YOL155C	intact:EBI-11525615|ensembl:ENSP00000328177	psi-mi:hpf1_yeast(display_long)|uniprotkb:HPF1(gene name)|psi-mi:HPF1(display_short)|uniprotkb:AOF1001(orf name)|uniprotkb:YOL155C(locus name)	psi-mi:g5e962_human(display_long)|uniprotkb:hCG_1644200(orf name)|uniprotkb:MAGEA11(gene name)|psi-mi:MAGEA11(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550880|imex:IM-24995-3291	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005515|refseq:NP_014487.1|interpro:IPR021031|mint:Q05164|ensemblfungi:YOL155C(gene)|ensemblfungi:YOL155C_mRNA(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0009277"(fungal-type cell wall)|go:"GO:0015926"(glucosidase activity)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0071944"(cell periphery)|reactome:R-SCE-983168	refseq:NP_001011544.1|ensembl:ENSG00000185247(gene)|ensembl:ENST00000333104(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016604"(nuclear body)|interpro:IPR002190(MAGE protein)|interpro:IPR021072|interpro:IPR030099|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:6bUWFxCsumvuNKLLVzCUfBbL1hA559292	rogid:sVB0aA6yibWUx/d2SE+pwpKKgtI9606	intact-crc:A94DDC28B0AE41CE|rigid:MrtZO7x5n7XkNf1XvaUun1iGWrU	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q06132	uniprotkb:P51116	intact:EBI-34377|uniprotkb:D6VYX6|ensemblfungi:YLR336C	intact:EBI-740459|uniprotkb:Q8WUM2|uniprotkb:Q86V09|uniprotkb:B2R9M2|uniprotkb:D3DTQ1|ensembl:ENSP00000250113	psi-mi:sgd1_yeast(display_long)|uniprotkb:SGD1(gene name)|psi-mi:SGD1(display_short)|uniprotkb:YLR336C(locus name)	psi-mi:fxr2_human(display_long)|uniprotkb:FXR2(gene name)|psi-mi:FXR2(display_short)|uniprotkb:FMR1L2(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550900|imex:IM-24995-3296	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013440.1|sgd:S000004328|mint:Q06132|dip:DIP-6333N|ensemblfungi:YLR336C(gene)|ensemblfungi:YLR336C_mRNA(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0006972"(hyperosmotic response)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0097078"(FAL1-SGD1 complex)|interpro:IPR003890(MIF4G-like, type 3)|interpro:IPR003891(Initiation factor eIF-4 gamma, MA3)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR016024(Armadillo-type fold)	interpro:IPR004087(K Homology)|refseq:NP_004851.2|ensembl:ENSG00000129245(gene)|ensembl:ENST00000250113(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0044326"(dendritic spine neck)|go:"GO:0045182"(translation regulator activity)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0098793"(presynapse)|go:"GO:1902737"(dendritic filopodium)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|interpro:IPR004088(K Homology, type 1)|interpro:IPR008395(Agenet)|interpro:IPR022034|interpro:IPR032172|interpro:IPR036612|interpro:IPR040148|interpro:IPR040472|interpro:IPR041560|mint:P51116|rcsb pdb:3H8Z	-	crc64:8EEFDB8258407FF3	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:FxZCxGejbcvEs/J2h1HEaWeVZLQ559292	rogid:NnYgyzD2NRGIO1ZHukr5qy44qRE9606	intact-crc:5B29BE2DA7D28F79|rigid:xnbyTlAhgT+HBCSkbj2gfqWlCOw	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P49760-3	uniprotkb:Q05947	intact:EBI-11535445|ensembl:ENSP00000354856|ensembl:ENSP00000459461	intact:EBI-33647|uniprotkb:D6VYM4|ensemblfungi:YLR224W	psi-mi:p49760-3(display_long)|uniprotkb:CDC-like kinase 2(gene name synonym)|uniprotkb:CLK2(gene name)|psi-mi:CLK2(display_short)	psi-mi:ucc1_yeast(display_long)|uniprotkb:UCC1(gene name)|psi-mi:UCC1(display_short)|uniprotkb:Ubiquitination of citrate synthase in the glyoxylate cycle protein 1(gene name synonym)|uniprotkb:YLR224W(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550888|imex:IM-24995-3293	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-750020(isoform-parent)|ensembl:ENSG00000176444(gene)|ensembl:ENSG00000261893(gene)|ensembl:ENST00000361168(transcript)|ensembl:ENST00000572269(transcript)|uniprotkb:P49760-3(isoform-parent)	sgd:S000004214|refseq:NP_013325.1|mint:Q05947|dip:DIP-1630N|ensemblfungi:YLR224W(gene)|ensemblfungi:YLR224W_mRNA(transcript)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0071406"(cellular response to methylmercury)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:wFw4PjPFbFOw5k9Fqay3nAen8ZI9606	rogid:HOR8NxxNEa6zV2RmL1mMWrvNfEk559292	intact-crc:563719A6F6199370|rigid:dM41zON6cboSe/Qro4ldVJD1YVw	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P38432	uniprotkb:Q05955	intact:EBI-945751|uniprotkb:B2R931|ensembl:ENSP00000240316	intact:EBI-34541|uniprotkb:D6VYM7|ensemblfungi:YLR227C	psi-mi:coil_human(display_long)|uniprotkb:COIL(gene name)|psi-mi:COIL(display_short)|uniprotkb:CLN80(gene name synonym)|uniprotkb:p80-coilin(gene name synonym)	psi-mi:ady4_yeast(display_long)|uniprotkb:ADY4(gene name)|psi-mi:ADY4(display_short)|uniprotkb:L8083.11(orf name)|uniprotkb:YLR227C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550892|imex:IM-24995-3294	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004636.1|dip:DIP-38503N|ensembl:ENSG00000121058(gene)|ensembl:ENST00000240316(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0015030"(Cajal body)|go:"GO:0016020"(membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0030619"(U1 snRNA binding)|go:"GO:0030620"(U2 snRNA binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR024822|interpro:IPR031722|mint:P38432	sgd:S000004217|refseq:NP_013328.1|dip:DIP-4786N|ensemblfungi:YLR227C(gene)|ensemblfungi:YLR227C_mRNA(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0030437"(ascospore formation)|go:"GO:0035974"(meiotic spindle pole body)|go:"GO:0051301"(cell division)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:hd5p6AbyA/GYNEeca99Mdb41qM09606	rogid:rYFhfauuzO793SGutv2Pee7hcBM559292	intact-crc:9A6776390D3D83B6|rigid:KMN+QdDdGOjToCWKTuBn3QggNs0	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q6UN15	uniprotkb:Q06102	intact:EBI-1021914|uniprotkb:Q0VGE0|uniprotkb:Q499Y4|uniprotkb:Q49AU3|uniprotkb:Q7Z608|uniprotkb:Q8WVN3|uniprotkb:Q96F80|uniprotkb:Q9H077|intact:EBI-11535474|ensembl:ENSP00000336752|uniprotkb:B4DIR3|uniprotkb:G3XAD6	intact:EBI-38049|uniprotkb:D6W4A5|ensemblfungi:YPR107C	psi-mi:fip1_human(display_long)|uniprotkb:Factor interacting with PAP(gene name synonym)|uniprotkb:FIP1-like 1 protein(gene name synonym)|uniprotkb:Rearranged in hypereosinophilia(gene name synonym)|uniprotkb:FIP1L1(gene name)|psi-mi:FIP1L1(display_short)|uniprotkb:FIP1(gene name synonym)|uniprotkb:RHE(gene name synonym)	psi-mi:yth1_yeast(display_long)|uniprotkb:Yeast 30 kDa homolog 1(gene name synonym)|uniprotkb:YTH1(gene name)|psi-mi:YTH1(display_short)|uniprotkb:YPR107C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550896|imex:IM-24995-3295	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000306932|ensembl:ENSP00000302993|ensembl:ENSP00000336752|ensembl:ENST00000358575|ensembl:ENSP00000351383|ensembl:ENST00000507922|ensembl:ENSP00000425456|refseq:NP_001128409.1|refseq:NP_001128410.1|refseq:NP_112179.2|ensembl:ENSG00000145216(gene)|ensembl:ENST00000337488(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|interpro:IPR007854(Fip1)|mint:Q6UN15|rcsb pdb:7K95|reactome:R-HSA-159231|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-77595|reactome:R-HSA-9673766|dip:DIP-42503N	refseq:NP_015432.1|sgd:S000006311|mint:Q06102|dip:DIP-2028N|ensemblfungi:YPR107C(gene)|ensemblfungi:YPR107C_mRNA(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR036855|rcsb pdb:6EOJ|reactome:R-SCE-77595	-	-	crc64:79C5993AE4E670EA	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/16	rogid:41uK1l8RV99q4k4Z7K9zeG3TJHA9606	rogid:rqNO3dAJtktR7RuM1ADpb9Nt0X8559292	intact-crc:F5068CD28E1788D1|rigid:fqElL4slW+Vuhpf1giO1nOAZ3po	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O15209	uniprotkb:Q06287	intact:EBI-723574|uniprotkb:Q5HYV4|uniprotkb:Q5STL0|uniprotkb:Q5STR7|uniprotkb:Q8WV82|ensembl:ENSP00000372683|ensembl:ENSP00000388191|ensembl:ENSP00000393514|ensembl:ENSP00000396292|ensembl:ENSP00000404403|ensembl:ENSP00000407545|uniprotkb:B0V007	intact:EBI-11979|ensemblfungi:YLR186W|uniprotkb:E9P8U2|uniprotkb:D6VYI9	psi-mi:zbt22_human(display_long)|uniprotkb:Zinc finger protein 297(gene name synonym)|uniprotkb:Protein BING1(gene name synonym)|uniprotkb:Zinc finger and BTB domain-containing protein 22A(gene name synonym)|uniprotkb:ZBTB22(gene name)|psi-mi:ZBTB22(display_short)|uniprotkb:BING1(gene name synonym)|uniprotkb:ZBTB22A(gene name synonym)|uniprotkb:ZNF297(gene name synonym)	psi-mi:nep1_yeast(display_long)|uniprotkb:EMG1(gene name)|psi-mi:EMG1(display_short)|uniprotkb:NEP1(gene name synonym)|uniprotkb:YLR186W(locus name)|uniprotkb:L9470.5(orf name)|uniprotkb:Nucleolar essential protein 1(gene name synonym)|uniprotkb:"18S rRNA (pseudouridine(1189)-N1)-methyltransferase"(gene name synonym)|uniprotkb:Essential for mitotic growth protein 1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550920|imex:IM-24995-3301	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001138810.1|refseq:NP_005444.4|ensembl:ENSG00000206280(gene)|ensembl:ENSG00000227780(gene)|ensembl:ENSG00000229253(gene)|ensembl:ENSG00000236104(gene)|ensembl:ENSG00000237056(gene)|ensembl:ENST00000418724(transcript)|ensembl:ENST00000431845(transcript)|ensembl:ENST00000445320(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR029833|interpro:IPR036236|ensembl:ENST00000383196(transcript)|ensembl:ENST00000416097(transcript)|ensembl:ENST00000418540(transcript)|dip:DIP-62047N	go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005880"(nuclear microtubule)|go:"GO:0006364"(rRNA processing)|go:"GO:0019843"(rRNA binding)|go:"GO:0030686"(90S preribosome)|go:"GO:0031167"(rRNA methylation)|go:"GO:0032040"(small-subunit processome)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0070037"("rRNA (pseudouridine) methyltransferase activity")|go:"GO:0070475"(rRNA base methylation)|interpro:IPR005304(Suppressor Mra1)|ensemblfungi:YLR186W(gene)|interpro:IPR029026|interpro:IPR029028|rcsb pdb:2V3J|rcsb pdb:2V3K|ensemblfungi:YLR186W_mRNA(transcript)|go:"GO:0000447"("endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000472"("endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000480"("endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0005634"(nucleus)|rcsb pdb:3OIJ|rcsb pdb:3OIN|rcsb pdb:5JPQ|rcsb pdb:5TZS|rcsb pdb:5WLC|rcsb pdb:5WYJ|rcsb pdb:5WYK|rcsb pdb:6KE6|rcsb pdb:6LQP|rcsb pdb:6LQQ|rcsb pdb:6LQR|rcsb pdb:6LQS|rcsb pdb:6LQT|rcsb pdb:6LQU|rcsb pdb:3OII|rcsb pdb:6LQV|rcsb pdb:6ZQA|rcsb pdb:6ZQB|rcsb pdb:6ZQC|rcsb pdb:6ZQD|rcsb pdb:6ZQE|rcsb pdb:6ZQF|rcsb pdb:6ZQG|rcsb pdb:7AJT|rcsb pdb:7AJU|sgd:S000004176|refseq:NP_013287.1|reactome:R-SCE-6791226|dip:DIP-6504N	-	-	crc64:4A8FCDA812051AD1	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:/u3Is9uJ0nS5Ru7xZKg4MqF6dzE9606	rogid:z62Fg9aJ4kKGgU5NIlAND2yHGrQ559292	intact-crc:E46930D5072CDFE0|rigid:UMN0yqxmM5sRZxe9fSOd2ELtnJY	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P38159	uniprotkb:Q06251	intact:EBI-743526|ensembl:ENSP00000359645|uniprotkb:Q5JQ67|uniprotkb:Q969R3|uniprotkb:D3DWH0|uniprotkb:E9PG86|uniprotkb:Q8N8Y7|uniprotkb:B4E3U4	intact:EBI-32907|uniprotkb:D6VYI1|ensemblfungi:YLR177W	psi-mi:rbmx_human(display_long)|uniprotkb:Glycoprotein p43(gene name synonym)|uniprotkb:RBMX(gene name)|psi-mi:RBMX(display_short)|uniprotkb:HNRPG(gene name synonym)|uniprotkb:RBMXP1(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein G(gene name synonym)	psi-mi:yl177_yeast(display_long)|uniprotkb:YLR177W(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550916|imex:IM-24995-3300	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000147274(gene)|ensembl:ENST00000320676(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000791"(euchromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0044530"(supraspliceosomal complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0006509"(membrane protein ectodomain proteolysis)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012604(RBM1CTR)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|mint:P38159|rcsb pdb:2MB0|rcsb pdb:2MKS|reactome:R-HSA-72163|reactome:R-HSA-72203|reactome:R-HSA-9013418|reactome:R-HSA-9013422|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273|refseq:NP_002130.2|refseq:NP_001158275.1|dip:DIP-34447N	refseq:NP_013278.1|sgd:S000004167|mint:Q06251|dip:DIP-4804N|ensemblfungi:YLR177W(gene)|ensemblfungi:YLR177W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|interpro:IPR007557(PSP1 C-terminal conserved region)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:ocCkdy9PxjeVLUQf0tMVCEhFfO89606	rogid:24pYGcKZbt39dfb9ITA+NxFPo0Y559292	intact-crc:D6A8B4E5B8FC6093|rigid:rSwQZlrHqP4qnxoHvnar+f6S5+I	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P38432	uniprotkb:Q06132	intact:EBI-945751|uniprotkb:B2R931|ensembl:ENSP00000240316	intact:EBI-34377|uniprotkb:D6VYX6|ensemblfungi:YLR336C	psi-mi:coil_human(display_long)|uniprotkb:COIL(gene name)|psi-mi:COIL(display_short)|uniprotkb:CLN80(gene name synonym)|uniprotkb:p80-coilin(gene name synonym)	psi-mi:sgd1_yeast(display_long)|uniprotkb:SGD1(gene name)|psi-mi:SGD1(display_short)|uniprotkb:YLR336C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550904|imex:IM-24995-3297	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004636.1|dip:DIP-38503N|ensembl:ENSG00000121058(gene)|ensembl:ENST00000240316(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0015030"(Cajal body)|go:"GO:0016020"(membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0030619"(U1 snRNA binding)|go:"GO:0030620"(U2 snRNA binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR024822|interpro:IPR031722|mint:P38432	refseq:NP_013440.1|sgd:S000004328|mint:Q06132|dip:DIP-6333N|ensemblfungi:YLR336C(gene)|ensemblfungi:YLR336C_mRNA(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0006972"(hyperosmotic response)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0097078"(FAL1-SGD1 complex)|interpro:IPR003890(MIF4G-like, type 3)|interpro:IPR003891(Initiation factor eIF-4 gamma, MA3)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR016024(Armadillo-type fold)	-	-	crc64:8EEFDB8258407FF3	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:hd5p6AbyA/GYNEeca99Mdb41qM09606	rogid:FxZCxGejbcvEs/J2h1HEaWeVZLQ559292	intact-crc:E580AC2DD57E2EA2|rigid:SO7As3jx3AzOgXxsft8fizVioPE	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q06178	uniprotkb:P63279	intact:EBI-11803|ensemblfungi:YLR328W|uniprotkb:D6VYX0	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	psi-mi:nma1_yeast(display_long)|uniprotkb:NMA1(gene name)|psi-mi:NMA1(display_short)|uniprotkb:"NAD(+) pyrophosphorylase 1"(gene name synonym)|uniprotkb:"NAD(+) diphosphorylase 1"(gene name synonym)|uniprotkb:Nicotinamide-nucleotide adenylyltransferase 1(gene name synonym)|uniprotkb:Nicotinate-nucleotide adenylyltransferase 1(gene name synonym)|uniprotkb:L8543.16(orf name)|uniprotkb:YLR328W(locus name)	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550908|imex:IM-24995-3298	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YLR328W(gene)|ensemblfungi:YLR328W_mRNA(transcript)|go:"GO:0000309"(nicotinamide-nucleotide adenylyltransferase activity)|go:"GO:0004515"(nicotinate-nucleotide adenylyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009435"(NAD biosynthetic process)|go:"GO:0042802"(identical protein binding)|interpro:IPR004821(Cytidyltransferase-related)|interpro:IPR005248(Probable nicotinate-nucleotide adenylyltransferase)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|reactome:R-SCE-196807|refseq:NP_013432.1|sgd:S000004320|dip:DIP-1228N|mint:Q06178	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N	-	crc64:A176964E56A30DD8	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:VzrKsykGbQsR8Eh7CHCwn/bCID8559292	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	intact-crc:49C917438CC284BC|rigid:2h914wn3NQRlmLY0vGS3NzozEBE	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P62258	uniprotkb:Q06251	intact:EBI-356498|uniprotkb:P29360|uniprotkb:P42655|uniprotkb:Q53XZ5|uniprotkb:Q63631|uniprotkb:Q7M4R4|uniprotkb:B3KY71|uniprotkb:D3DTH5|uniprotkb:Q4VJB6|ensembl:ENSP00000264335|ensembl:ENSP00000487356	intact:EBI-32907|uniprotkb:D6VYI1|ensemblfungi:YLR177W	psi-mi:1433e_human(display_long)|uniprotkb:YWHAE(gene name)|psi-mi:YWHAE(display_short)	psi-mi:yl177_yeast(display_long)|uniprotkb:YLR177W(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550912|imex:IM-24995-3299	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006752.1|dip:DIP-36676N|reactome:R-HSA-1445148|reactome:R-HSA-2028269|reactome:R-HSA-205025|reactome:R-HSA-2565942|reactome:R-HSA-3371453|reactome:R-HSA-3371511|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-75035|reactome:R-HSA-8854518|reactome:R-HSA-8862803|reactome:R-HSA-8876198|ensembl:ENSG00000108953(gene)|ensembl:ENSG00000274474(gene)|ensembl:ENST00000264335(transcript)|ensembl:ENST00000627231(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0003064"(regulation of heart rate by hormone)|go:"GO:0003723"(RNA binding)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005925"(focal adhesion)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050815"(phosphoserine residue binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099072"(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:"GO:1901016"(regulation of potassium ion transmembrane transporter activity)|go:"GO:1901020"(negative regulation of calcium ion transmembrane transporter activity)|go:"GO:1902309"(negative regulation of peptidyl-serine dephosphorylation)|go:"GO:1905913"(negative regulation of calcium ion export across plasma membrane)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P62258|rcsb pdb:2BR9|rcsb pdb:3UAL|rcsb pdb:3UBW|rcsb pdb:6EIH|rcsb pdb:7C8E|reactome:R-HSA-111447	refseq:NP_013278.1|sgd:S000004167|mint:Q06251|dip:DIP-4804N|ensemblfungi:YLR177W(gene)|ensemblfungi:YLR177W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|interpro:IPR007557(PSP1 C-terminal conserved region)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:mnuAjdnQZbMFojll2PnV3xFklXQ9606	rogid:24pYGcKZbt39dfb9ITA+NxFPo0Y559292	intact-crc:62F3290F26008EEF|rigid:i2S8lHUrARRRAcIR3XbOtl9ht4o	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q05D60	uniprotkb:Q06411	intact:EBI-748597|uniprotkb:Q8NEF1|uniprotkb:Q96LL7|intact:EBI-10177066|uniprotkb:E9PJR5|ensembl:ENSP00000298050	intact:EBI-576|uniprotkb:D6VZ60|ensemblfungi:YLR424W	psi-mi:deup1_human(display_long)|uniprotkb:CCDC67(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 67(gene name synonym)|uniprotkb:DEUP1(gene name)|psi-mi:DEUP1(display_short)	psi-mi:sp382_yeast(display_long)|uniprotkb:NTR1(gene name synonym)|uniprotkb:YLR424W(locus name)|uniprotkb:SPP382(gene name)|psi-mi:SPP382(display_short)|uniprotkb:CCF8(gene name synonym)|uniprotkb:Suppressor of PRP38 protein 2(gene name synonym)|uniprotkb:Nineteen complex-related protein 1(gene name synonym)|uniprotkb:CLF1 complex factor 8(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550940|imex:IM-24995-3306	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_857596.2|refseq:XP_005273859.1|ensembl:ENSG00000165325(gene)|ensembl:ENST00000298050(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005814"(centriole)|go:"GO:0007099"(centriole replication)|go:"GO:0042802"(identical protein binding)|go:"GO:0098535"(de novo centriole assembly involved in multi-ciliated epithelial cell differentiation)|go:"GO:0098536"(deuterosome)|go:"GO:1903251"(multi-ciliated epithelial cell differentiation)|interpro:IPR029611|interpro:IPR031470|go:"GO:0030030"(cell projection organization)	refseq:NP_013528.1|sgd:S000004416|dip:DIP-1491N|mint:Q06411|ensemblfungi:YLR424W(gene)|ensemblfungi:YLR424W_mRNA(transcript)|go:"GO:0000349"(generation of catalytic spliceosome for first transesterification step)|go:"GO:0000390"(spliceosomal complex disassembly)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0071008"(U2-type post-mRNA release spliceosomal complex)|go:"GO:1904876"(negative regulation of DNA ligase activity)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR000467(D111/G-patch)|rcsb pdb:5Y88	-	-	crc64:9986B547B9582338	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:/d2HVFtI68hr7u7nqJdBUwn06bE9606	rogid:HrG54vTE2zs7jxPSzi+9eeA23/k559292	intact-crc:72F20E3ABDEBF201|rigid:8PqKGM3lyIAAkFS+iM5UgSYr6zg	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q06411	uniprotkb:P38432	intact:EBI-576|uniprotkb:D6VZ60|ensemblfungi:YLR424W	intact:EBI-945751|uniprotkb:B2R931|ensembl:ENSP00000240316	psi-mi:sp382_yeast(display_long)|uniprotkb:NTR1(gene name synonym)|uniprotkb:YLR424W(locus name)|uniprotkb:SPP382(gene name)|psi-mi:SPP382(display_short)|uniprotkb:CCF8(gene name synonym)|uniprotkb:Suppressor of PRP38 protein 2(gene name synonym)|uniprotkb:Nineteen complex-related protein 1(gene name synonym)|uniprotkb:CLF1 complex factor 8(gene name synonym)	psi-mi:coil_human(display_long)|uniprotkb:COIL(gene name)|psi-mi:COIL(display_short)|uniprotkb:CLN80(gene name synonym)|uniprotkb:p80-coilin(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550936|imex:IM-24995-3305	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013528.1|sgd:S000004416|dip:DIP-1491N|mint:Q06411|ensemblfungi:YLR424W(gene)|ensemblfungi:YLR424W_mRNA(transcript)|go:"GO:0000349"(generation of catalytic spliceosome for first transesterification step)|go:"GO:0000390"(spliceosomal complex disassembly)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0071008"(U2-type post-mRNA release spliceosomal complex)|go:"GO:1904876"(negative regulation of DNA ligase activity)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR000467(D111/G-patch)|rcsb pdb:5Y88	refseq:NP_004636.1|dip:DIP-38503N|ensembl:ENSG00000121058(gene)|ensembl:ENST00000240316(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0015030"(Cajal body)|go:"GO:0016020"(membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0030619"(U1 snRNA binding)|go:"GO:0030620"(U2 snRNA binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR024822|interpro:IPR031722|mint:P38432	-	crc64:9986B547B9582338	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:HrG54vTE2zs7jxPSzi+9eeA23/k559292	rogid:hd5p6AbyA/GYNEeca99Mdb41qM09606	intact-crc:808A6B84174D57A2|rigid:kt448FdSg/2TjseZenFZiXDSbyE	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q06340	uniprotkb:P63279	intact:EBI-33799|uniprotkb:D6VSZ1|ensemblfungi:YDR363W	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	psi-mi:esc2_yeast(display_long)|uniprotkb:YDR363W(locus name)|uniprotkb:ESC2(gene name)|psi-mi:ESC2(display_short)|uniprotkb:Establishes silent chromatin protein 2(gene name synonym)	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550924|imex:IM-24995-3302	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010650.1|sgd:S000002771|dip:DIP-5219N|ensemblfungi:YDR363W(gene)|ensemblfungi:YDR363W_mRNA(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0033235"(positive regulation of protein sumoylation)|interpro:IPR000626(Ubiquitin)|interpro:IPR022617|interpro:IPR029071	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N	-	crc64:F691FB73ED2FAF15	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:LgEXHq17g/of0LB8TeMRHcceivk559292	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	intact-crc:C202C1249B4939AA|rigid:RE7bWgGGogHJBLPghe37QCyAJF4	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q06389	uniprotkb:P01011	intact:EBI-11946|ensemblfungi:YDR373W|uniprotkb:D6VT04	intact:EBI-296557|uniprotkb:Q9UC47|uniprotkb:Q13703|uniprotkb:Q2TU87|uniprotkb:Q2TU88|uniprotkb:Q59GP9|uniprotkb:Q6LBY8|uniprotkb:Q6LDT7|uniprotkb:Q6NSC9|uniprotkb:Q8N177|uniprotkb:Q96DW8|uniprotkb:Q9UNU9|uniprotkb:B3KVQ7|ensembl:ENSP00000376793|ensembl:ENSP00000376795|ensembl:ENSP00000450540	psi-mi:ncs1_yeast(display_long)|uniprotkb:FRQ1(gene name)|psi-mi:FRQ1(display_short)|uniprotkb:NCS1(gene name synonym)|uniprotkb:YDR373W(locus name)|uniprotkb:D9481.6(orf name)	psi-mi:aact_human(display_long)|uniprotkb:Cell growth-inhibiting gene 24/25 protein(gene name synonym)|uniprotkb:SERPINA3(gene name)|psi-mi:SERPINA3(display_short)|uniprotkb:AACT(gene name synonym)|uniprotkb:GIG24(orf name)|uniprotkb:GIG25(orf name)|uniprotkb:Serpin A3(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550928|imex:IM-24995-3303	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YDR373W(gene)|ensemblfungi:YDR373W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0033101"(cellular bud membrane)|go:"GO:0043128"(positive regulation of 1-phosphatidylinositol 4-kinase activity)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR028846|rcsb pdb:1FPW|rcsb pdb:2JU0|reactome:R-SCE-2514859|refseq:NP_010661.3|sgd:S000002781|mint:Q06389|dip:DIP-2733N	go:"GO:0006953"(acute-phase response)|refseq:NP_001076.2|ensembl:ENSG00000196136(gene)|ensembl:ENST00000393078(transcript)|ensembl:ENST00000393080(transcript)|ensembl:ENST00000467132(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|reactome:R-HSA-6798695|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0030277"(maintenance of gastrointestinal epithelium)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|interpro:IPR000215(Protease inhibitor I4, serpin)|go:"GO:0006954"(inflammatory response)|interpro:IPR023795|interpro:IPR023796|go:"GO:0010951"(negative regulation of endopeptidase activity)|interpro:IPR036186|interpro:IPR042178|interpro:IPR042185|mint:P01011|rcsb pdb:1AS4|rcsb pdb:1QMN|rcsb pdb:2ACH|rcsb pdb:3CAA|rcsb pdb:3DLW|rcsb pdb:4CAA|rcsb pdb:6HGE|reactome:R-HSA-114608	-	crc64:5E9D7F48F8AADA21	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:8mxxTP8CHNx24fQcjCxgDE7xhbs559292	rogid:LTdrRsWwtOm8QvOWZ4h0SO8EuP09606	intact-crc:4A5209F5BEC131FF|rigid:n9tp04GjADA1tlOpNF09vF0RG90	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q06408	uniprotkb:O75071	intact:EBI-32807|uniprotkb:D6VT13|ensemblfungi:YDR380W	intact:EBI-2805635|ensembl:ENSP00000361001|uniprotkb:Q5SXB8|uniprotkb:D3DQ23	psi-mi:aro10_yeast(display_long)|uniprotkb:ARO10(gene name)|psi-mi:ARO10(display_short)|uniprotkb:YDR380W(locus name)|uniprotkb:D9481.3(orf name)|uniprotkb:Transaminated branched-chain amino acid decarboxylase(gene name synonym)|uniprotkb:Thiamine diphosphate-dependent phenylpyruvate decarboxylase(gene name synonym)|uniprotkb:Thiamine pyrophosphate-dependent 2-oxo-acid decarboxylase(gene name synonym)	psi-mi:efc14_human(display_long)|uniprotkb:EFCAB14(gene name)|psi-mi:EFCAB14(display_short)|uniprotkb:KIAA0494(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550932|imex:IM-24995-3304	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002788|refseq:NP_010668.3|dip:DIP-5252N|mint:Q06408|ensemblfungi:YDR380W(gene)|ensemblfungi:YDR380W_mRNA(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000949"(aromatic amino acid family catabolic process to alcohol via Ehrlich pathway)|go:"GO:0000950"(branched-chain amino acid catabolic process to alcohol via Ehrlich pathway)|go:"GO:0000951"(methionine catabolic process to 3-methylthiopropanol)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006552"(leucine catabolic process)|go:"GO:0006559"(L-phenylalanine catabolic process)|go:"GO:0006569"(tryptophan catabolic process)|go:"GO:0006572"(tyrosine catabolic process)|go:"GO:0016831"(carboxy-lyase activity)|go:"GO:0030976"(thiamine pyrophosphate binding)|go:"GO:0047433"(branched-chain-2-oxoacid decarboxylase activity)|go:"GO:0047434"(indolepyruvate decarboxylase activity)|go:"GO:0050177"(phenylpyruvate decarboxylase activity)|go:"GO:0050546"(4-hydroxyphenylpyruvate decarboxylase activity)|interpro:IPR011766(Thiamine pyrophosphate enzyme, C-terminal TPP-binding)|interpro:IPR012000(Thiamine pyrophosphate enzyme, central region)|interpro:IPR012001(Thiamine pyrophosphate enzyme, N-terminal TPP binding region)|interpro:IPR012110(Pyruvate decarboxylase/indolepyruvate decarboxylase)|interpro:IPR029035|interpro:IPR029061	ensembl:ENSG00000159658(gene)|ensembl:ENST00000371933(transcript)|go:"GO:0005509"(calcium ion binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR042352|refseq:NP_055589.1	-	crc64:616DF7E06DA82415	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:jh443SvRXK8vb+GUjPq95NB8jdU559292	rogid:UhD1cgnq+/XOmI2Y7LZ7ANpf9wA9606	intact-crc:3C66E8E4A2E8115D|rigid:6mjUoJ6yUoAOiX3za3cyKoGN3Nw	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O43586	uniprotkb:Q06630	intact:EBI-1050964|uniprotkb:O43585|uniprotkb:O95657|uniprotkb:B5BUK4|uniprotkb:B5BU74|ensembl:ENSP00000452746	intact:EBI-36794|uniprotkb:D6VSS5|ensemblfungi:YDR296W	psi-mi:ppip1_human(display_long)|uniprotkb:CD2-binding protein 1(gene name synonym)|uniprotkb:H-PIP(gene name synonym)|uniprotkb:PSTPIP1(gene name)|psi-mi:PSTPIP1(display_short)|uniprotkb:CD2BP1(gene name synonym)	psi-mi:mhr1_yeast(display_long)|uniprotkb:MHR1(gene name)|psi-mi:MHR1(display_short)|uniprotkb:YDR296W(locus name)|uniprotkb:Cross-linked transcription component 1(gene name synonym)|uniprotkb:XTC1(gene name synonym)|uniprotkb:Mitochondrial large ribosomal subunit protein mL67(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550960|imex:IM-24995-3311	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003969.2|refseq:NP_001308064.1|refseq:NP_001308066.1|ensembl:ENSG00000140368(gene)|ensembl:ENST00000558012(transcript)|go:"GO:0001931"(uropod)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0006954"(inflammatory response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0032154"(cleavage furrow)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051015"(actin filament binding)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR027267|interpro:IPR030777|interpro:IPR031160|interpro:IPR036028|mint:O43586|rcsb pdb:2DIL|reactome:R-HSA-844456|reactome:R-HSA-9660826	sgd:S000002704|refseq:NP_010582.3|mint:Q06630|dip:DIP-5727N|ensemblfungi:YDR296W(gene)|ensemblfungi:YDR296W_mRNA(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0000150"(DNA strand exchange activity)|go:"GO:0003677"(DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0006310"(DNA recombination)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0032543"(mitochondrial translation)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0090297"(positive regulation of mitochondrial DNA replication)|interpro:IPR024629|rcsb pdb:3J6B|rcsb pdb:5MRC|rcsb pdb:5MRE|rcsb pdb:5MRF	-	-	crc64:F26903A4814091C4	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:JWK4dCYdcVF6mKwe+hoOri1wwps9606	rogid:eA38S7UNOpP716XSQ0zzhYm2TqA559292	intact-crc:D62E8A5108554C7C|rigid:AWoM5SLQmf4iBA6nWh7+UiNOxcU	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q06630	uniprotkb:O95751	intact:EBI-36794|uniprotkb:D6VSS5|ensemblfungi:YDR296W	intact:EBI-740738|ensembl:ENSP00000359557|uniprotkb:Q6IAR6	psi-mi:mhr1_yeast(display_long)|uniprotkb:MHR1(gene name)|psi-mi:MHR1(display_short)|uniprotkb:YDR296W(locus name)|uniprotkb:Cross-linked transcription component 1(gene name synonym)|uniprotkb:XTC1(gene name synonym)|uniprotkb:Mitochondrial large ribosomal subunit protein mL67(gene name synonym)	psi-mi:ldoc1_human(display_long)|uniprotkb:Leucine zipper protein down-regulated in cancer cells(gene name synonym)|uniprotkb:LDOC1(gene name)|psi-mi:LDOC1(display_short)|uniprotkb:BCUR1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550956|imex:IM-24995-3310	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002704|refseq:NP_010582.3|mint:Q06630|dip:DIP-5727N|ensemblfungi:YDR296W(gene)|ensemblfungi:YDR296W_mRNA(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0000150"(DNA strand exchange activity)|go:"GO:0003677"(DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0006310"(DNA recombination)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0032543"(mitochondrial translation)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0090297"(positive regulation of mitochondrial DNA replication)|interpro:IPR024629|rcsb pdb:3J6B|rcsb pdb:5MRC|rcsb pdb:5MRE|rcsb pdb:5MRF	refseq:NP_036449.1|ensembl:ENSG00000182195(gene)|ensembl:ENST00000370526(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071225"(cellular response to muramyl dipeptide)|interpro:IPR032549|interpro:IPR032567	-	crc64:F26903A4814091C4	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:eA38S7UNOpP716XSQ0zzhYm2TqA559292	rogid:Ediu0oNiZ/+YVY8l3fNdgP5A+v09606	intact-crc:1B3776E2139A88E7|rigid:kvTpwC03DfjelXlTES8y8iAK6q0	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8N5R6	uniprotkb:Q06543	intact:EBI-740841|intact:EBI-953781|uniprotkb:B3KQ49|uniprotkb:A8K3U4|uniprotkb:A8MPQ6|uniprotkb:A8MV61|uniprotkb:A8MVU9|uniprotkb:Q9H5Q6|uniprotkb:Q8TAX6|intact:EBI-2320546|intact:EBI-11522976	intact:EBI-33132|uniprotkb:D6VYP1|ensemblfungi:YLR243W	psi-mi:ccd33_human(display_long)|uniprotkb:CCDC33(gene name)|psi-mi:CCDC33(display_short)|uniprotkb:Cancer/testis antigen 61(gene name synonym)	psi-mi:gpn3_yeast(display_long)|uniprotkb:GPN3(gene name)|psi-mi:GPN3(display_short)|uniprotkb:YLR243W(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550944|imex:IM-24995-3307	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_079331.3|interpro:IPR000008(C2 calcium-dependent membrane targeting)|go:"GO:0005777"(peroxisome)|refseq:NP_001274110.1|refseq:NP_877592.2|mint:Q8N5R6|interpro:IPR035892|interpro:IPR039889	refseq:NP_013344.1|sgd:S000004233|dip:DIP-1911N|ensemblfungi:YLR243W(gene)|ensemblfungi:YLR243W_mRNA(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007064"(mitotic sister chromatid cohesion)|interpro:IPR004130(Protein of unknown function, ATP binding)|interpro:IPR027417|interpro:IPR030228	-	-	crc64:96E478B8DD5988BB	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2021/11/30	rogid:eEIn7pQyfdHWx8TeLJpYy0i/gww9606	rogid:XGJg0/XoYEbfio5kpjB/7Q9Cvjc559292	intact-crc:405D3D9CA3F26EB9|rigid:M7pDBzuMW3ZgO/PQHF9jUqOW4og	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q06630	uniprotkb:O95273	intact:EBI-36794|uniprotkb:D6VSS5|ensemblfungi:YDR296W	intact:EBI-748961|uniprotkb:A8K3Q0|uniprotkb:A8K3U2|uniprotkb:Q6ZQN9|uniprotkb:Q7Z519|uniprotkb:Q8NBS7|uniprotkb:Q8NBY2|uniprotkb:Q9NS19|uniprotkb:Q9NYH3|uniprotkb:Q9UHX9|ensembl:ENSP00000300213	psi-mi:mhr1_yeast(display_long)|uniprotkb:MHR1(gene name)|psi-mi:MHR1(display_short)|uniprotkb:YDR296W(locus name)|uniprotkb:Cross-linked transcription component 1(gene name synonym)|uniprotkb:XTC1(gene name synonym)|uniprotkb:Mitochondrial large ribosomal subunit protein mL67(gene name synonym)	psi-mi:ccdb1_human(display_long)|uniprotkb:Grap2 and cyclin-D-interacting protein(gene name synonym)|uniprotkb:Human homolog of Maid(gene name synonym)|uniprotkb:CCNDBP1(gene name)|psi-mi:CCNDBP1(display_short)|uniprotkb:DIP1(gene name synonym)|uniprotkb:GCIP(gene name synonym)|uniprotkb:HHM(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550948|imex:IM-24995-3308	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002704|refseq:NP_010582.3|mint:Q06630|dip:DIP-5727N|ensemblfungi:YDR296W(gene)|ensemblfungi:YDR296W_mRNA(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0000150"(DNA strand exchange activity)|go:"GO:0003677"(DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0006310"(DNA recombination)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0032543"(mitochondrial translation)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0090297"(positive regulation of mitochondrial DNA replication)|interpro:IPR024629|rcsb pdb:3J6B|rcsb pdb:5MRC|rcsb pdb:5MRE|rcsb pdb:5MRF	refseq:NP_036274.3|ensembl:ENSG00000166946(gene)|ensembl:ENST00000300213(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0016604"(nuclear body)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR026907|mint:O95273|rcsb pdb:3AY5	-	crc64:F26903A4814091C4	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:eA38S7UNOpP716XSQ0zzhYm2TqA559292	rogid:Vi9aoFc+Mov6P3X6KGmsTxXqxvM9606	intact-crc:3ABAF36FBA7442BE|rigid:LtjyODNWPNiD5flamYEvq88v7kM	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O15156-2	uniprotkb:Q06630	intact:EBI-11522250|ensembl:ENSP00000406286	intact:EBI-36794|uniprotkb:D6VSS5|ensemblfungi:YDR296W	psi-mi:o15156-2(display_long)|uniprotkb:ZBTB7B(gene name)|psi-mi:ZBTB7B(display_short)|uniprotkb:Krueppel-related zinc finger protein cKrox(gene name synonym)|uniprotkb:T-helper-inducing POZ/Krueppel-like factor(gene name synonym)|uniprotkb:ZBTB15(gene name synonym)|uniprotkb:ZFP67(gene name synonym)|uniprotkb:ZNF857B(gene name synonym)|uniprotkb:Zinc finger and BTB domain-containing protein 15(gene name synonym)|uniprotkb:Zinc finger protein 67 homolog(gene name synonym)|uniprotkb:Zinc finger protein 857B(gene name synonym)|uniprotkb:Zinc finger protein Th-POK(gene name synonym)	psi-mi:mhr1_yeast(display_long)|uniprotkb:MHR1(gene name)|psi-mi:MHR1(display_short)|uniprotkb:YDR296W(locus name)|uniprotkb:Cross-linked transcription component 1(gene name synonym)|uniprotkb:XTC1(gene name synonym)|uniprotkb:Mitochondrial large ribosomal subunit protein mL67(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550952|imex:IM-24995-3309	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-740434(isoform-parent)|ensembl:ENSG00000160685(gene)|ensembl:ENST00000417934(transcript)|uniprotkb:O15156-2(isoform-parent)	sgd:S000002704|refseq:NP_010582.3|mint:Q06630|dip:DIP-5727N|ensemblfungi:YDR296W(gene)|ensemblfungi:YDR296W_mRNA(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0000150"(DNA strand exchange activity)|go:"GO:0003677"(DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0006310"(DNA recombination)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0032543"(mitochondrial translation)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0090297"(positive regulation of mitochondrial DNA replication)|interpro:IPR024629|rcsb pdb:3J6B|rcsb pdb:5MRC|rcsb pdb:5MRE|rcsb pdb:5MRF	-	isoform-comment:No experimental confirmation available.	crc64:F26903A4814091C4	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:41NEFYyprTXI+fOHVFh78TPKF289606	rogid:eA38S7UNOpP716XSQ0zzhYm2TqA559292	intact-crc:96F567F6593EB0B1|rigid:+gIfruCDlLpKi5ABf+MA+5VAKWI	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q06630	uniprotkb:O14641	intact:EBI-36794|uniprotkb:D6VSS5|ensemblfungi:YDR296W	intact:EBI-740850|ensembl:ENSP00000005340|uniprotkb:Q53XM0|uniprotkb:D3DTN3	psi-mi:mhr1_yeast(display_long)|uniprotkb:MHR1(gene name)|psi-mi:MHR1(display_short)|uniprotkb:YDR296W(locus name)|uniprotkb:Cross-linked transcription component 1(gene name synonym)|uniprotkb:XTC1(gene name synonym)|uniprotkb:Mitochondrial large ribosomal subunit protein mL67(gene name synonym)	psi-mi:dvl2_human(display_long)|uniprotkb:DSH homolog 2(gene name synonym)|uniprotkb:DVL2(gene name)|psi-mi:DVL2(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550968|imex:IM-24995-3313	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002704|refseq:NP_010582.3|mint:Q06630|dip:DIP-5727N|ensemblfungi:YDR296W(gene)|ensemblfungi:YDR296W_mRNA(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0000150"(DNA strand exchange activity)|go:"GO:0003677"(DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0006310"(DNA recombination)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0032543"(mitochondrial translation)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0090297"(positive regulation of mitochondrial DNA replication)|interpro:IPR024629|rcsb pdb:3J6B|rcsb pdb:5MRC|rcsb pdb:5MRE|rcsb pdb:5MRF	refseq:NP_004413.1|ensembl:ENSG00000004975(gene)|ensembl:ENST00000005340(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005109"(frizzled binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0007507"(heart development)|go:"GO:0016235"(aggresome)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044340"(canonical Wnt signaling pathway involved in regulation of cell proliferation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0150012"(positive regulation of neuron projection arborization)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008341(Dishevelled-2 region)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:O14641|rcsb pdb:2REY|rcsb pdb:3CBX|rcsb pdb:3CBY|rcsb pdb:3CBZ|rcsb pdb:3CC0|rcsb pdb:4WIP|rcsb pdb:5LNP|rcsb pdb:5SUY|rcsb pdb:5SUZ|rcsb pdb:6IW3|rcsb pdb:6JCK|reactome:R-HSA-201681|reactome:R-HSA-201688|reactome:R-HSA-2028269|reactome:R-HSA-4086400|reactome:R-HSA-4608870|reactome:R-HSA-4641258|reactome:R-HSA-4641262|reactome:R-HSA-5099900|reactome:R-HSA-5368598|reactome:R-HSA-5663220|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9673324|ensembl:ENSP00000005340|dip:DIP-34433N	-	crc64:F26903A4814091C4	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:eA38S7UNOpP716XSQ0zzhYm2TqA559292	rogid:2Vdc8oRnT4Mz/j+EXQXrL3AszOc9606	intact-crc:7383709020078895|rigid:KfACV2u1KAa7GX/3udfMqHYgtRY	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q06630	uniprotkb:Q08379	intact:EBI-36794|uniprotkb:D6VSS5|ensemblfungi:YDR296W	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	psi-mi:mhr1_yeast(display_long)|uniprotkb:MHR1(gene name)|psi-mi:MHR1(display_short)|uniprotkb:YDR296W(locus name)|uniprotkb:Cross-linked transcription component 1(gene name synonym)|uniprotkb:XTC1(gene name synonym)|uniprotkb:Mitochondrial large ribosomal subunit protein mL67(gene name synonym)	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550964|imex:IM-24995-3312	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002704|refseq:NP_010582.3|mint:Q06630|dip:DIP-5727N|ensemblfungi:YDR296W(gene)|ensemblfungi:YDR296W_mRNA(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0000150"(DNA strand exchange activity)|go:"GO:0003677"(DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0006310"(DNA recombination)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0032543"(mitochondrial translation)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0090297"(positive regulation of mitochondrial DNA replication)|interpro:IPR024629|rcsb pdb:3J6B|rcsb pdb:5MRC|rcsb pdb:5MRE|rcsb pdb:5MRF	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N	-	crc64:F26903A4814091C4	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2017/05/26	rogid:eA38S7UNOpP716XSQ0zzhYm2TqA559292	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	intact-crc:3AA79D29F31A180D|rigid:gl2QUcrSam/JZf9Zt3jttWwEaDQ	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P51116	uniprotkb:Q06667	intact:EBI-740459|uniprotkb:Q8WUM2|uniprotkb:Q86V09|uniprotkb:B2R9M2|uniprotkb:D3DTQ1|ensembl:ENSP00000250113	intact:EBI-33838|uniprotkb:D6VSU4|ensemblfungi:YDR315C	psi-mi:fxr2_human(display_long)|uniprotkb:FXR2(gene name)|psi-mi:FXR2(display_short)|uniprotkb:FMR1L2(gene name synonym)	psi-mi:ipk1_yeast(display_long)|uniprotkb:IPK1(gene name)|psi-mi:IPK1(display_short)|uniprotkb:GSL1(gene name synonym)|uniprotkb:Inositol-1,3,4,5,6-pentakisphosphate 2-kinase(gene name synonym)|uniprotkb:"Ins(1,3,4,5,6)P5 2-kinase"(gene name synonym)|uniprotkb:YDR315C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550972|imex:IM-24995-3314	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR004087(K Homology)|refseq:NP_004851.2|ensembl:ENSG00000129245(gene)|ensembl:ENST00000250113(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0044326"(dendritic spine neck)|go:"GO:0045182"(translation regulator activity)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0098793"(presynapse)|go:"GO:1902737"(dendritic filopodium)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|interpro:IPR004088(K Homology, type 1)|interpro:IPR008395(Agenet)|interpro:IPR022034|interpro:IPR032172|interpro:IPR036612|interpro:IPR040148|interpro:IPR040472|interpro:IPR041560|mint:P51116|rcsb pdb:3H8Z	sgd:S000002723|reactome:R-SCE-1855167|reactome:R-SCE-1855191|refseq:NP_010601.3|dip:DIP-1388N|ensemblfungi:YDR315C(gene)|ensemblfungi:YDR315C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0032958"(inositol phosphate biosynthetic process)|go:"GO:0035299"(inositol pentakisphosphate 2-kinase activity)|go:"GO:0052746"(inositol phosphorylation)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|interpro:IPR009286(Protein of unknown function DUF941)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:NnYgyzD2NRGIO1ZHukr5qy44qRE9606	rogid:Fd1kGHt2rvWznhiE9yFCTiLo2oY559292	intact-crc:E80E836F5A292E57|rigid:8Gufg/KxGSlSinauyqQH63xULZc	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P19012	uniprotkb:Q06707	intact:EBI-739566|uniprotkb:Q53XV8|uniprotkb:Q9BUG4|uniprotkb:B3KQY1|uniprotkb:B3KRA2|uniprotkb:E0CX14|ensembl:ENSP00000254043|ensembl:ENSP00000377546	intact:EBI-32671|uniprotkb:D6VZ20|ensemblfungi:YLR385C	psi-mi:k1c15_human(display_long)|uniprotkb:KRT15(gene name)|psi-mi:KRT15(display_short)|uniprotkb:KRTB(gene name synonym)|uniprotkb:Cytokeratin-15(gene name synonym)|uniprotkb:Keratin-15(gene name synonym)	psi-mi:swc7_yeast(display_long)|uniprotkb:SWC7(gene name)|psi-mi:SWC7(display_short)|uniprotkb:AWS1(gene name synonym)|uniprotkb:YLR385C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550976|imex:IM-24995-3315	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002266.2|ensembl:ENSG00000171346(gene)|ensembl:ENST00000254043(transcript)|ensembl:ENST00000393976(transcript)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0008544"(epidermis development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097110"(scaffold protein binding)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR039008|mint:P19012|reactome:R-HSA-6805567|reactome:R-HSA-6809371	refseq:NP_013489.1|sgd:S000004377|dip:DIP-4645N|mint:Q06707|ensemblfungi:YLR385C(gene)|ensemblfungi:YLR385C_mRNA(transcript)|go:"GO:0000812"(Swr1 complex)|go:"GO:0005634"(nucleus)|go:"GO:0006338"(chromatin remodeling)|interpro:IPR020195	-	-	crc64:92CCE2FF3DCE72F1	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:WrZQBYQvrWcfrR5ojWXrXp6spPE9606	rogid:7DWWay9S3JHtIRpmJHyHeELBg5M559292	intact-crc:F5DA06CAACCE8A82|rigid:T1Rwcy8baI7wPgKD8u8cgVBiNEw	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q06707	uniprotkb:P37198	intact:EBI-32671|uniprotkb:D6VZ20|ensemblfungi:YLR385C	intact:EBI-347978|intact:EBI-28983799|ensembl:ENSP00000305503|ensembl:ENSP00000407331|ensembl:ENSP00000471191|ensembl:ENSP00000473192|uniprotkb:Q6GTM2|uniprotkb:Q503A4|uniprotkb:Q96C43|uniprotkb:Q9NSL1|uniprotkb:B3KWU5	psi-mi:swc7_yeast(display_long)|uniprotkb:SWC7(gene name)|psi-mi:SWC7(display_short)|uniprotkb:AWS1(gene name synonym)|uniprotkb:YLR385C(locus name)	psi-mi:nup62_human(display_long)|uniprotkb:NUP62(gene name)|psi-mi:NUP62(display_short)|uniprotkb:62 kDa nucleoporin(gene name synonym)|uniprotkb:Nucleoporin Nup62(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550980|imex:IM-24995-3316	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013489.1|sgd:S000004377|dip:DIP-4645N|mint:Q06707|ensemblfungi:YLR385C(gene)|ensemblfungi:YLR385C_mRNA(transcript)|go:"GO:0000812"(Swr1 complex)|go:"GO:0005634"(nucleus)|go:"GO:0006338"(chromatin remodeling)|interpro:IPR020195	refseq:NP_714941.1|ensembl:ENSG00000213024(gene)|ensembl:ENST00000352066(transcript)|ensembl:ENST00000422090(transcript)|ensembl:ENST00000596217(transcript)|ensembl:ENST00000597029(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005642"(annulate lamellae)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007100"(mitotic centrosome separation)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007569"(cell aging)|go:"GO:0008219"(cell death)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0003682"(chromatin binding)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0019894"(kinesin binding)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042306"(regulation of protein import into nucleus)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043069"(negative regulation of programmed cell death)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045742"(positive regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046578"(regulation of Ras protein signal transduction)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0046601"(positive regulation of centriole replication)|go:"GO:0051028"(mRNA transport)|go:"GO:0051425"(PTB domain binding)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0072686"(mitotic spindle)|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|go:"GO:0090543"(Flemming body)|go:"GO:0098534"(centriole assembly)|go:"GO:1903438"(positive regulation of mitotic cytokinetic process)|go:"GO:1904781"(positive regulation of protein localization to centrosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR007758(Nucleoporin, Nsp1-like, C-terminal)|interpro:IPR026010|interpro:IPR033072|mint:P37198|rcsb pdb:2H4D|rcsb pdb:5IJN|rcsb pdb:5IJO|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|refseq:NP_714940.1|refseq:NP_001180286.1|refseq:NP_036478.2|refseq:NP_057637.2|ensembl:ENSP00000305503|ensembl:ENSP00000407331|ensembl:ENSP00000471191|ensembl:ENSP00000473192|dip:DIP-29749N	-	crc64:92CCE2FF3DCE72F1	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:7DWWay9S3JHtIRpmJHyHeELBg5M559292	rogid:v7mvKvTtVEnLMwcpUZIcdAzge009606	intact-crc:CEB269F211C6E7C3|rigid:LmH67keCrwmZ13ODEvS29CWwdkw	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q07540	uniprotkb:A0A024R0Y4	intact:EBI-2206814|uniprotkb:D6VRN0|ensemblfungi:YDL120W	intact:EBI-11523730|ensembl:ENSP00000477709|ensembl:ENSP00000478363|ensembl:ENSP00000481091	psi-mi:frda_yeast(display_long)|uniprotkb:YFH1(gene name)|psi-mi:YFH1(display_short)|uniprotkb:YDL120W(locus name)	psi-mi:a0a024r0y4_human(display_long)|uniprotkb:TADA2A(gene name)|psi-mi:TADA2A(display_short)|uniprotkb:TADA2L(gene name synonym)|uniprotkb:hCG_28187(orf name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551000|imex:IM-24995-3321	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-7485N|refseq:NP_010163.1|sgd:S000002278|mint:Q07540|ensemblfungi:YDL120W(gene)|ensemblfungi:YDL120W_mRNA(transcript)|go:"GO:0004322"(ferroxidase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006121"(mitochondrial electron transport, succinate to ubiquinone)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0006783"(heme biosynthetic process)|go:"GO:0006811"(ion transport)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008199"(ferric iron binding)|go:"GO:0010040"("response to iron(II) ion")|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0018283"(iron incorporation into metallo-sulfur cluster)|go:"GO:0034986"(iron chaperone activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|interpro:IPR002908(Frataxin-like)|interpro:IPR017789(Frataxin)|interpro:IPR020895|interpro:IPR036524|rcsb pdb:2FQL|rcsb pdb:2GA5|rcsb pdb:3OEQ|rcsb pdb:3OER|rcsb pdb:4EC2|rcsb pdb:5T0V|rcsb pdb:5TRE|reactome:R-SCE-1268020|reactome:R-SCE-1362409|go:"GO:0008198"(ferrous iron binding)	refseq:NP_001159577.2|refseq:NP_001479.4|ensembl:ENSG00000276234(gene)|ensembl:ENST00000612272(transcript)|ensembl:ENST00000615182(transcript)|ensembl:ENST00000620628(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031063"(regulation of histone deacetylation)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0035065"(regulation of histone acetylation)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090043"(regulation of tubulin deacetylation)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016827(Transcriptional adaptor 2)|interpro:IPR017884|interpro:IPR017930|interpro:IPR036388|interpro:IPR041983|interpro:IPR043145	-	crc64:AB1FF7478EF0E5D6	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:4UcroTodEXb/5+xHGpnXDXf/rd8559292	rogid:IGh7vC68gMLe+tAVGM4gc0rzc6Y9606	intact-crc:6A6B0F9F6E577CCC|rigid:ATP/kj+Z6lPImhni88ySl6WER7c	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q08379	uniprotkb:Q07379	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	intact:EBI-2342994|uniprotkb:D6VRT9|ensemblfungi:YDL057W	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:yd057_yeast(display_long)|uniprotkb:YDL057W(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550996|imex:IM-24995-3320	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N	sgd:S000002215|refseq:NP_010226.1|interpro:IPR022742|interpro:IPR029058|ensemblfungi:YDL057W(gene)|ensemblfungi:YDL057W_mRNA(transcript)|go:"GO:0016020"(membrane)|go:"GO:0016298"(lipase activity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2017/05/26	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	rogid:U0Sf+t16Ti+vYEOEePrGjlqflhQ559292	intact-crc:934243E744C43113|rigid:t/tkMK4SbkVX9DfY0HE+ECrpGW4	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O43765	uniprotkb:Q06810	intact:EBI-347996|ensembl:ENSP00000221566|ensembl:ENSP00000503397|ensembl:ENSP00000504495|uniprotkb:Q9BTZ9|intact:EBI-1045243|uniprotkb:Q6FIA9|uniprotkb:D6W610	intact:EBI-2068557|uniprotkb:D6W479|uniprotkb:Q6B149|ensemblfungi:YPR075C	psi-mi:sgta_human(display_long)|uniprotkb:SGTA(gene name)|psi-mi:SGTA(display_short)|uniprotkb:SGT(gene name synonym)|uniprotkb:Alpha-SGT(gene name synonym)|uniprotkb:Vpu-binding protein(gene name synonym)|uniprotkb:SGT1(gene name synonym)	psi-mi:opy2_yeast(display_long)|uniprotkb:OPY2(gene name)|psi-mi:OPY2(display_short)|uniprotkb:Overproduction-induced pheromone-resistant protein 2(gene name synonym)|uniprotkb:YPR075C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550984|imex:IM-24995-3317	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:4CPG|rcsb pdb:4GOD|rcsb pdb:4GOE|rcsb pdb:4GOF|reactome:R-HSA-9609523|rcsb pdb:2VYI|ensembl:ENSG00000104969(gene)|ensembl:ENST00000221566(transcript)|ensembl:ENST00000676943(transcript)|ensembl:ENST00000677149(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072380"(TRC complex)|go:"GO:0098850"(extrinsic component of synaptic vesicle membrane)|go:"GO:1903070"(negative regulation of ER-associated ubiquitin-dependent protein catabolic process)|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)|go:"GO:1903646"(positive regulation of chaperone-mediated protein folding)|go:"GO:1904288"(BAT3 complex binding)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR032374|mint:O43765|refseq:XP_011526480.1|refseq:NP_003012.1	refseq:NP_015400.1|sgd:S000006279|interpro:IPR018571|mint:Q06810|ensemblfungi:YPR075C(gene)|ensemblfungi:YPR075C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000751"(mitotic cell cycle G1 arrest in response to pheromone)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007231"(osmosensory signaling pathway)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:1900436"(positive regulation of filamentous growth of a population of unicellular organisms in response to starvation)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:r/Cyj4UJk/cS8QdrbjhTZMPCigI9606	rogid:avNmi6o7WtIkxIyUvhoboBXL8sc559292	intact-crc:7E7F315958CEB4FC|rigid:TCNluPxabzIjedlLFatvZqtighs	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q06892	uniprotkb:O95544	intact:EBI-13701|uniprotkb:Q08928|uniprotkb:D6W3I1|ensemblfungi:YPL188W	intact:EBI-743949|uniprotkb:Q9H931|uniprotkb:A8K296|uniprotkb:A6NNN3|uniprotkb:B7Z434|uniprotkb:F5GXR5|uniprotkb:Q5QPS4|uniprotkb:Q9H2P2|ensembl:ENSP00000341679|ensembl:ENSP00000344340	psi-mi:pos5_yeast(display_long)|uniprotkb:POS5(gene name)|psi-mi:POS5(display_short)|uniprotkb:YPL188W(locus name)	psi-mi:nadk_human(display_long)|uniprotkb:"Poly(P)/ATP NAD kinase"(gene name synonym)|uniprotkb:NADK(gene name)|psi-mi:NADK(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550988|imex:IM-24995-3318	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000006109|refseq:NP_015136.1|ensemblfungi:YPL188W(gene)|ensemblfungi:YPL188W_mRNA(transcript)|go:"GO:0003951"(NAD+ kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006741"(NADP biosynthetic process)|go:"GO:0019674"(NAD metabolic process)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0042736"(NADH kinase activity)|interpro:IPR002504(ATP-NAD/AcoX kinase)|interpro:IPR016064(ATP-NAD kinase, PpnK-type)|interpro:IPR017437(ATP-NAD kinase, PpnK-type, all-beta)|interpro:IPR017438(ATP-NAD kinase, PpnK-type, alpha/beta)|rcsb pdb:3AFO|dip:DIP-5503N	refseq:NP_001185922.1|refseq:NP_001185923.1|refseq:NP_001185924.1|refseq:NP_075394.3|refseq:XP_005244835.1|refseq:XP_006710900.1|ensembl:ENSG00000008130(gene)|ensembl:ENST00000341426(transcript)|ensembl:ENST00000341991(transcript)|go:"GO:0003951"(NAD+ kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006741"(NADP biosynthetic process)|go:"GO:0016310"(phosphorylation)|go:"GO:0019674"(NAD metabolic process)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046872"(metal ion binding)|interpro:IPR002504(ATP-NAD/AcoX kinase)|interpro:IPR016064(ATP-NAD kinase, PpnK-type)|interpro:IPR017437(ATP-NAD kinase, PpnK-type, all-beta)|interpro:IPR017438(ATP-NAD kinase, PpnK-type, alpha/beta)|mint:O95544|rcsb pdb:3PFN|reactome:R-HSA-196807	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:4n8TcpxeCYBUCHDHMqmxXeNsiGg559292	rogid:XPfRviZiKsV+1JOUi7BsMrIa3M49606	intact-crc:CB3FB18EC2B3C504|rigid:UBiQvKC4Vp5FyW8BDGGA5N6aQmM	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q07379	uniprotkb:P35520	intact:EBI-2342994|uniprotkb:D6VRT9|ensemblfungi:YDL057W	intact:EBI-740135|uniprotkb:Q99425|uniprotkb:Q9BWC5|uniprotkb:B2R993|uniprotkb:D3DSK4|intact:EBI-14245939|ensembl:ENSP00000344460|ensembl:ENSP00000352643|ensembl:ENSP00000381225|ensembl:ENSP00000381231	psi-mi:yd057_yeast(display_long)|uniprotkb:YDL057W(locus name)	psi-mi:cbs_human(display_long)|uniprotkb:CBS(gene name)|psi-mi:CBS(display_short)|uniprotkb:Serine sulfhydrase(gene name synonym)|uniprotkb:Beta-thionase(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11550992|imex:IM-24995-3319	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002215|refseq:NP_010226.1|interpro:IPR022742|interpro:IPR029058|ensemblfungi:YDL057W(gene)|ensemblfungi:YDL057W_mRNA(transcript)|go:"GO:0016020"(membrane)|go:"GO:0016298"(lipase activity)	refseq:NP_000062.1|refseq:NP_001171479.1|refseq:NP_001171480.1|ensembl:ENSG00000160200(gene)|ensembl:ENST00000352178(transcript)|ensembl:ENST00000359624(transcript)|ensembl:ENST00000398158(transcript)|go:"GO:0004122"(cystathionine beta-synthase activity)|ensembl:ENST00000398165(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006535"(cysteine biosynthetic process from serine)|go:"GO:0006563"(L-serine metabolic process)|go:"GO:0006565"(L-serine catabolic process)|go:"GO:0019343"(cysteine biosynthetic process via cystathionine)|go:"GO:0019344"(cysteine biosynthetic process)|go:"GO:0019346"(transsulfuration)|go:"GO:0019448"(L-cysteine catabolic process)|go:"GO:0019825"(oxygen binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0020037"(heme binding)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042262"(DNA protection)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043418"(homocysteine catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0050421"("nitrite reductase (NO-forming) activity")|go:"GO:0050667"(homocysteine metabolic process)|go:"GO:0070025"(carbon monoxide binding)|go:"GO:0070026"(nitric oxide binding)|go:"GO:0070814"(hydrogen sulfide biosynthetic process)|go:"GO:0072341"(modified amino acid binding)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR001216(Cysteine synthase/cystathionine beta-synthase P-phosphate-binding site)|interpro:IPR001926(Pyridoxal phosphate-dependent enzyme, beta subunit)|interpro:IPR005857(Cystathionine beta-synthase)|interpro:IPR036052|mint:P35520|rcsb pdb:1JBQ|rcsb pdb:1M54|rcsb pdb:4COO|rcsb pdb:4L0D|rcsb pdb:4L27|rcsb pdb:4L28|rcsb pdb:4L3V|rcsb pdb:4PCU|rcsb pdb:4UUU|rcsb pdb:5MMS|reactome:R-HSA-1614603|reactome:R-HSA-2408508|refseq:XP_011528079.1|refseq:XP_011528083.1|refseq:XP_011528084.1|refseq:XP_011544396.1|refseq:XP_011544397.1|refseq:XP_011544399.1|refseq:XP_011544400.1|refseq:XP_011544401.1|refseq:NP_001307227.1|refseq:NP_001308002.1|refseq:XP_016883700.1|refseq:XP_016883701.1|refseq:XP_016883702.1|refseq:XP_016883703.1|refseq:XP_016883704.1|refseq:XP_016883705.1|refseq:XP_016883706.1|refseq:XP_016883707.1|refseq:XP_016883978.1|refseq:XP_016883979.1|refseq:XP_016883980.1|refseq:XP_016883981.1	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:U0Sf+t16Ti+vYEOEePrGjlqflhQ559292	rogid:f9eo0cPOHppVY7Nqejag3YyK18s9606	intact-crc:4AD3937A5AE0A066|rigid:T9PY+yIXzgaFi35EqGJeQoGF1As	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q08273	uniprotkb:O95198	intact:EBI-31686|uniprotkb:D6W1T5|ensemblfungi:YOL133W	intact:EBI-746999|uniprotkb:B2RD18|uniprotkb:Q8N484|uniprotkb:Q8TBH5|uniprotkb:A6NCM7|uniprotkb:B4DFH7|uniprotkb:F5H6M3|ensembl:ENSP00000226725	psi-mi:rbx1_yeast(display_long)|uniprotkb:E3 ubiquitin-protein ligase complex SCF subunit HRT1(gene name synonym)|uniprotkb:High level expression reduces Ty3 transposition protein 1(gene name synonym)|uniprotkb:HRT1(gene name)|psi-mi:HRT1(display_short)|uniprotkb:RBX1(gene name synonym)|uniprotkb:ROC1(gene name synonym)|uniprotkb:Regulator of cullins protein 1(gene name synonym)|uniprotkb:YOL133W(locus name)	psi-mi:klhl2_human(display_long)|uniprotkb:Actin-binding protein Mayven(gene name synonym)|uniprotkb:KLHL2(gene name)|psi-mi:KLHL2(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551020|imex:IM-24995-3326	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014508.1|sgd:S000005493|dip:DIP-1373N|mint:Q08273|ensemblfungi:YOL133W(gene)|ensemblfungi:YOL133W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0035361"(Cul8-RING ubiquitin ligase complex)|go:"GO:0051301"(cell division)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097602"(cullin family protein binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR024766|reactome:R-SCE-5696395|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-68949|reactome:R-SCE-8854050|reactome:R-SCE-8951664|reactome:R-SCE-983168	refseq:NP_001154993.1|refseq:NP_001154994.1|refseq:NP_009177.3|refseq:NP_001317952.1|refseq:NP_001317953.1|refseq:XP_016863165.1|ensembl:ENSG00000109466(gene)|ensembl:ENST00000226725(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030027"(lamellipodium)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR017096(Kelch-like protein, gigaxonin)|interpro:IPR044072|mint:O95198|rcsb pdb:2XN4|rcsb pdb:4CHB|reactome:R-HSA-8951664|reactome:R-HSA-983168|go:"GO:0042802"(identical protein binding)	-	crc64:A9C3193E48CAF881	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:7LBUfvb6zpWuPkbMDrEAnrMuJj8559292	rogid:tFegR2lJZccRqs4qUjdT3PNjNnk9606	intact-crc:347EBB9A8F950CF5|rigid:+ylwumnTyxVdpdyc4oGWKo865Bg	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O43791	uniprotkb:Q08273	intact:EBI-743549|uniprotkb:Q53HJ1|uniprotkb:B2R6S3|uniprotkb:D3DTW7|ensembl:ENSP00000240327|ensembl:ENSP00000377001|ensembl:ENSP00000420908|ensembl:ENSP00000424119|ensembl:ENSP00000425905|ensembl:ENSP00000426986|ensembl:ENSP00000499562	intact:EBI-31686|uniprotkb:D6W1T5|ensemblfungi:YOL133W	psi-mi:spop_human(display_long)|uniprotkb:HIB homolog 1(gene name synonym)|uniprotkb:Roadkill homolog 1(gene name synonym)|uniprotkb:SPOP(gene name)|psi-mi:SPOP(display_short)	psi-mi:rbx1_yeast(display_long)|uniprotkb:E3 ubiquitin-protein ligase complex SCF subunit HRT1(gene name synonym)|uniprotkb:High level expression reduces Ty3 transposition protein 1(gene name synonym)|uniprotkb:HRT1(gene name)|psi-mi:HRT1(display_short)|uniprotkb:RBX1(gene name synonym)|uniprotkb:ROC1(gene name synonym)|uniprotkb:Regulator of cullins protein 1(gene name synonym)|uniprotkb:YOL133W(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551016|imex:IM-24995-3325	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001007227.1|refseq:NP_001007228.1|refseq:NP_001007229.1|refseq:NP_001007230.1|refseq:NP_001007231.1|refseq:NP_003554.1|refseq:XP_005257780.1|refseq:XP_005257781.1|ensembl:ENSG00000121067(gene)|ensembl:ENST00000347630(transcript)|ensembl:ENST00000393328(transcript)|ensembl:ENST00000503676(transcript)|ensembl:ENST00000504102(transcript)|ensembl:ENST00000509079(transcript)|ensembl:ENST00000514121(transcript)|ensembl:ENST00000665825(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0016607"(nuclear speck)|go:"GO:0030162"(regulation of proteolysis)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR034089|mint:O43791|rcsb pdb:2CR2|rcsb pdb:3HQH|rcsb pdb:3HQI|rcsb pdb:3HQL|rcsb pdb:3HQM|rcsb pdb:3HSV|rcsb pdb:3HTM|rcsb pdb:3HU6|rcsb pdb:3IVB|rcsb pdb:3IVQ|rcsb pdb:3IVV|rcsb pdb:4EOZ|rcsb pdb:4HS2|rcsb pdb:4J8Z|rcsb pdb:4O1V|rcsb pdb:6F8F|rcsb pdb:6F8G|rcsb pdb:6I41|rcsb pdb:6I5P|rcsb pdb:6I68|rcsb pdb:6I7A|rcsb pdb:7D3D|rcsb pdb:7LIN|rcsb pdb:7LIO|rcsb pdb:7LIP|rcsb pdb:7LIQ|reactome:R-HSA-5632684|go:"GO:0005634"(nucleus)|refseq:XP_016880693.1|dip:DIP-50517N	refseq:NP_014508.1|sgd:S000005493|dip:DIP-1373N|mint:Q08273|ensemblfungi:YOL133W(gene)|ensemblfungi:YOL133W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0035361"(Cul8-RING ubiquitin ligase complex)|go:"GO:0051301"(cell division)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097602"(cullin family protein binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR024766|reactome:R-SCE-5696395|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-68949|reactome:R-SCE-8854050|reactome:R-SCE-8951664|reactome:R-SCE-983168	-	-	crc64:A9C3193E48CAF881	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:PC9ofpvk14xwTnnqT590/YRnx/49606	rogid:7LBUfvb6zpWuPkbMDrEAnrMuJj8559292	intact-crc:95ED20042B92B7E2|rigid:6/futgV6DhTWGv/wADWCfT5Ndw4	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O96006	uniprotkb:Q07887	intact:EBI-740037|uniprotkb:Q96BY4|ensembl:ENSP00000370616|ensembl:ENSP00000370620|ensembl:ENSP00000370621|ensembl:ENSP00000498725	intact:EBI-33243|uniprotkb:D6VXV9|ensemblfungi:YLL049W	psi-mi:zbed1_human(display_long)|uniprotkb:ZBED1(gene name)|psi-mi:ZBED1(display_short)|uniprotkb:ALTE(gene name synonym)|uniprotkb:DREF(gene name synonym)|uniprotkb:KIAA0785(gene name synonym)|uniprotkb:TRAMP(gene name synonym)|uniprotkb:dREF homolog(gene name synonym)|uniprotkb:Putative Ac-like transposable element(gene name synonym)|uniprotkb:DNA replication-related element-binding factor(gene name synonym)|uniprotkb:Zinc finger BED domain-containing protein 1(gene name synonym)|uniprotkb:hDREF(gene name synonym)	psi-mi:ldb18_yeast(display_long)|uniprotkb:Low dye-binding protein 18(gene name synonym)|uniprotkb:LDB18(gene name)|psi-mi:LDB18(display_short)|uniprotkb:YLL049W(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551004|imex:IM-24995-3322	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164606.1|refseq:NP_001164607.1|refseq:NP_004720.1|ensembl:ENSG00000214717(gene)|ensembl:ENST00000381218(transcript)|ensembl:ENST00000381222(transcript)|ensembl:ENST00000381223(transcript)|ensembl:ENST00000652001(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0031965"(nuclear membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044828"(negative regulation by host of viral genome replication)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0061665"(SUMO ligase activity)|go:"GO:1990466"(protein autosumoylation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003656(Zinc finger, BED-type predicted)|interpro:IPR008906(HAT dimerisation)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR036236|mint:O96006|rcsb pdb:2CT5|reactome:R-HSA-4551638|go:"GO:0005813"(centrosome)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016605"(PML body)	sgd:S000003972|refseq:NP_013051.1|dip:DIP-1932N|ensemblfungi:YLL049W(gene)|ensemblfungi:YLL049W_mRNA(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0005869"(dynactin complex)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:jl97ZV2Kz5YAmQKktWt/wk7OkRw9606	rogid:oTvD3VEb0ZAfYezSviDPi8wVGxg559292	intact-crc:322149B831C5C713|rigid:LMPnmhfxp/6331BqlNLbAhctQcA	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8N5R6	uniprotkb:Q07951	intact:EBI-740841|intact:EBI-953781|uniprotkb:B3KQ49|uniprotkb:A8K3U4|uniprotkb:A8MPQ6|uniprotkb:A8MV61|uniprotkb:A8MVU9|uniprotkb:Q9H5Q6|uniprotkb:Q8TAX6|intact:EBI-2320546|intact:EBI-11522976	intact:EBI-31959|uniprotkb:D6VY23|ensemblfungi:YLR021W	psi-mi:ccd33_human(display_long)|uniprotkb:CCDC33(gene name)|psi-mi:CCDC33(display_short)|uniprotkb:Cancer/testis antigen 61(gene name synonym)	psi-mi:poc3_yeast(display_long)|uniprotkb:POC3(gene name synonym)|uniprotkb:Increased recombination centers protein 25(gene name synonym)|uniprotkb:IRC25(gene name)|psi-mi:IRC25(display_short)|uniprotkb:DMP2(gene name synonym)|uniprotkb:YLR021W(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551008|imex:IM-24995-3323	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_079331.3|interpro:IPR000008(C2 calcium-dependent membrane targeting)|go:"GO:0005777"(peroxisome)|refseq:NP_001274110.1|refseq:NP_877592.2|mint:Q8N5R6|interpro:IPR035892|interpro:IPR039889	refseq:NP_013121.1|sgd:S000004011|dip:DIP-4747N|mint:Q07951|ensemblfungi:YLR021W(gene)|ensemblfungi:YLR021W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043248"(proteasome assembly)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|interpro:IPR018854|rcsb pdb:2Z5B|rcsb pdb:2Z5C	-	-	crc64:6CA25E8ED0491EE2	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2021/11/30	rogid:eEIn7pQyfdHWx8TeLJpYy0i/gww9606	rogid:5xcWnXqOt0DxQvelDvtc8ob2bj0559292	intact-crc:F93518F081B24F2B|rigid:k/XPBxFV+++TO+0BhS/Z4sYVhQQ	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:G5E962	uniprotkb:Q07978	intact:EBI-11525615|ensembl:ENSP00000328177	intact:EBI-38683|uniprotkb:D6VY33|ensemblfungi:YLR031W	psi-mi:g5e962_human(display_long)|uniprotkb:hCG_1644200(orf name)|uniprotkb:MAGEA11(gene name)|psi-mi:MAGEA11(display_short)	psi-mi:yl031_yeast(display_long)|uniprotkb:YLR031W(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551012|imex:IM-24995-3324	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001011544.1|ensembl:ENSG00000185247(gene)|ensembl:ENST00000333104(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016604"(nuclear body)|interpro:IPR002190(MAGE protein)|interpro:IPR021072|interpro:IPR030099|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899	sgd:S000004021|refseq:NP_013131.1|dip:DIP-4435N|ensemblfungi:YLR031W(gene)|ensemblfungi:YLR031W_mRNA(transcript)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:sVB0aA6yibWUx/d2SE+pwpKKgtI9606	rogid:T3r2tgTMVd+abiwf7/Ccb/QJ2ZQ559292	intact-crc:9B143D4582335BEF|rigid:9pXV7NJ/j3aIqFAFo5bgeW9LAzI	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q0VDD7	uniprotkb:Q03973	intact:EBI-741210|ensembl:ENSP00000465822|ensembl:ENSP00000500215|uniprotkb:Q13411|uniprotkb:Q8N825|uniprotkb:Q96D63|uniprotkb:Q9BU49	intact:EBI-33047|uniprotkb:D6VSF6|ensemblfungi:YDR174W	psi-mi:brme1_human(display_long)|uniprotkb:BRME1(gene name)|psi-mi:BRME1(display_short)|uniprotkb:C19orf57(gene name synonym)|uniprotkb:Pre-T/NK cell-associated protein 3B3(gene name synonym)	psi-mi:hmo1_yeast(display_long)|uniprotkb:HMO1(gene name)|psi-mi:HMO1(display_short)|uniprotkb:High spontaneous mutagenesis protein 2(gene name synonym)|uniprotkb:HSM2(gene name synonym)|uniprotkb:YD9395.07(orf name)|uniprotkb:YDR174W(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551040|imex:IM-24995-3331	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_077299.3|ensembl:ENSG00000132016(gene)|ensembl:ENSG00000288152(gene)|ensembl:ENST00000586783(transcript)|ensembl:ENST00000672170(transcript)|go:"GO:0005694"(chromosome)|go:"GO:0007144"(female meiosis I)|go:"GO:0007275"(multicellular organism development)|go:"GO:0007283"(spermatogenesis)|go:"GO:1990918"(double-strand break repair involved in meiotic recombination)|interpro:IPR031441|refseq:NP_001332773.1	refseq:NP_010459.1|sgd:S000002581|mint:Q03973|dip:DIP-1687N|ensemblfungi:YDR174W(gene)|ensemblfungi:YDR174W_mRNA(transcript)|go:"GO:0000400"(four-way junction DNA binding)|go:"GO:0001174"(transcriptional start site selection at RNA polymerase II promoter)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006265"(DNA topological change)|go:"GO:0006323"(DNA packaging)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006356"(regulation of transcription by RNA polymerase I)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0030261"(chromosome condensation)|go:"GO:0032040"(small-subunit processome)|go:"GO:0033553"(rDNA heterochromatin)|go:"GO:0044804"(autophagy of nucleus)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0060962"(regulation of ribosomal protein gene transcription by RNA polymerase II)|go:"GO:0070550"(rDNA condensation)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR036910|reactome:R-SCE-140342|reactome:R-SCE-5620971|reactome:R-SCE-5686938|reactome:R-SCE-6798695	-	-	crc64:3D6DCD56A28B7D77	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:YUbAjs5ZmWOPWRA9kq5qRZRioR49606	rogid:9sHGPuUbReXRmvQYqKvnd4fWBd4559292	intact-crc:A10DF6207F108D8B|rigid:mqvSRvkWXmonNANRgMPSVNi47EY	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q08981	uniprotkb:P62258	intact:EBI-2345174|uniprotkb:D6W3A3|ensemblfungi:YPL267W	intact:EBI-356498|uniprotkb:P29360|uniprotkb:P42655|uniprotkb:Q53XZ5|uniprotkb:Q63631|uniprotkb:Q7M4R4|uniprotkb:B3KY71|uniprotkb:D3DTH5|uniprotkb:Q4VJB6|ensembl:ENSP00000264335|ensembl:ENSP00000487356	psi-mi:acm1_yeast(display_long)|uniprotkb:ACM1(gene name)|psi-mi:ACM1(display_short)|uniprotkb:YPL267W(locus name)	psi-mi:1433e_human(display_long)|uniprotkb:YWHAE(gene name)|psi-mi:YWHAE(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551036|imex:IM-24995-3330	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000006188|refseq:NP_015056.1|dip:DIP-8871N|mint:Q08981|ensemblfungi:YPL267W(gene)|ensemblfungi:YPL267W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0051301"(cell division)|go:"GO:0055105"(ubiquitin-protein transferase inhibitor activity)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|rcsb pdb:4BH6	refseq:NP_006752.1|dip:DIP-36676N|reactome:R-HSA-1445148|reactome:R-HSA-2028269|reactome:R-HSA-205025|reactome:R-HSA-2565942|reactome:R-HSA-3371453|reactome:R-HSA-3371511|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-75035|reactome:R-HSA-8854518|reactome:R-HSA-8862803|reactome:R-HSA-8876198|ensembl:ENSG00000108953(gene)|ensembl:ENSG00000274474(gene)|ensembl:ENST00000264335(transcript)|ensembl:ENST00000627231(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0003064"(regulation of heart rate by hormone)|go:"GO:0003723"(RNA binding)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005925"(focal adhesion)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050815"(phosphoserine residue binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099072"(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:"GO:1901016"(regulation of potassium ion transmembrane transporter activity)|go:"GO:1901020"(negative regulation of calcium ion transmembrane transporter activity)|go:"GO:1902309"(negative regulation of peptidyl-serine dephosphorylation)|go:"GO:1905913"(negative regulation of calcium ion export across plasma membrane)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P62258|rcsb pdb:2BR9|rcsb pdb:3UAL|rcsb pdb:3UBW|rcsb pdb:6EIH|rcsb pdb:7C8E|reactome:R-HSA-111447	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:WiRejHsJpiS1aSY3PJUzdRflynM559292	rogid:mnuAjdnQZbMFojll2PnV3xFklXQ9606	intact-crc:3E39937725813F6E|rigid:ilpXeDffZ4W4kHLt6mvDI0gWYeY	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P63279	uniprotkb:Q08581	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	intact:EBI-38556|uniprotkb:D6W2Q4|ensemblfungi:YOR195W	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:slk19_yeast(display_long)|uniprotkb:Synthetic lethal KAR3 protein 19(gene name synonym)|uniprotkb:SLK19(gene name)|psi-mi:SLK19(display_short)|uniprotkb:YOR195W(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551024|imex:IM-24995-3327	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N	sgd:S000005721|refseq:NP_014838.3|mint:Q08581|dip:DIP-2595N|ensemblfungi:YOR195W(gene)|ensemblfungi:YOR195W_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0005819"(spindle)|go:"GO:0005874"(microtubule)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007097"(nuclear migration)|go:"GO:0031536"(positive regulation of exit from mitosis)|go:"GO:0051233"(spindle midzone)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0098653"(centromere clustering)|interpro:IPR024312	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	rogid:3ufBU9ElgshvxT7WluCx2lQX2Rs559292	intact-crc:D30DBFB56CCCB604|rigid:siA94kDoSEEwM7+nLStLP0Fb7w8	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q08909	uniprotkb:O14641	intact:EBI-36654|uniprotkb:D6W378|ensemblfungi:YOR385W	intact:EBI-740850|ensembl:ENSP00000005340|uniprotkb:Q53XM0|uniprotkb:D3DTN3	psi-mi:yo385_yeast(display_long)|uniprotkb:YOR385W(locus name)	psi-mi:dvl2_human(display_long)|uniprotkb:DSH homolog 2(gene name synonym)|uniprotkb:DVL2(gene name)|psi-mi:DVL2(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551028|imex:IM-24995-3328	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005912|refseq:NP_015030.3|dip:DIP-4047N|ensemblfungi:YOR385W(gene)|ensemblfungi:YOR385W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)	refseq:NP_004413.1|ensembl:ENSG00000004975(gene)|ensembl:ENST00000005340(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005109"(frizzled binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0007507"(heart development)|go:"GO:0016235"(aggresome)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044340"(canonical Wnt signaling pathway involved in regulation of cell proliferation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0150012"(positive regulation of neuron projection arborization)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008341(Dishevelled-2 region)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:O14641|rcsb pdb:2REY|rcsb pdb:3CBX|rcsb pdb:3CBY|rcsb pdb:3CBZ|rcsb pdb:3CC0|rcsb pdb:4WIP|rcsb pdb:5LNP|rcsb pdb:5SUY|rcsb pdb:5SUZ|rcsb pdb:6IW3|rcsb pdb:6JCK|reactome:R-HSA-201681|reactome:R-HSA-201688|reactome:R-HSA-2028269|reactome:R-HSA-4086400|reactome:R-HSA-4608870|reactome:R-HSA-4641258|reactome:R-HSA-4641262|reactome:R-HSA-5099900|reactome:R-HSA-5368598|reactome:R-HSA-5663220|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9673324|ensembl:ENSP00000005340|dip:DIP-34433N	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:8SWTqlDNdzFcWIa8miL9cz87Peg559292	rogid:2Vdc8oRnT4Mz/j+EXQXrL3AszOc9606	intact-crc:2D03E51FE98D8401|rigid:jgeiMmVQa2XQYTNFI1203W6IS4w	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O00308	uniprotkb:Q08909	intact:EBI-743923|uniprotkb:H3BRF3|uniprotkb:Q6ZTQ5|uniprotkb:A6NEP1|uniprotkb:Q96CZ2|uniprotkb:Q9BWN6|uniprotkb:B2R706|uniprotkb:B4DTL5|uniprotkb:F5H213|uniprotkb:I3RSG8|ensembl:ENSP00000352069	intact:EBI-36654|uniprotkb:D6W378|ensemblfungi:YOR385W	psi-mi:wwp2_human(display_long)|uniprotkb:WW domain-containing protein 2(gene name synonym)|uniprotkb:Atrophin-1-interacting protein 2(gene name synonym)|uniprotkb:WWP2(gene name)|psi-mi:WWP2(display_short)|uniprotkb:HECT-type E3 ubiquitin transferase WWP2(gene name synonym)	psi-mi:yo385_yeast(display_long)|uniprotkb:YOR385W(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551032|imex:IM-24995-3329	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_008945.2|refseq:NP_001257383.1|refseq:NP_001257384.1|refseq:XP_011521125.1|refseq:XP_011521127.1|refseq:XP_011521128.1|refseq:NP_001257382.1|refseq:NP_955456.1|refseq:XP_016878368.1|refseq:XP_016878369.1|refseq:XP_016878370.1|ensembl:ENSG00000198373(gene)|ensembl:ENST00000359154(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006858"(extracellular transport)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032410"(negative regulation of transporter activity)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0051224"(negative regulation of protein transport)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:1901016"(regulation of potassium ion transmembrane transporter activity)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000569(HECT)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR024928|interpro:IPR035892|interpro:IPR035983|interpro:IPR036020|mint:O00308|rcsb pdb:4Y07|rcsb pdb:5TJ7|rcsb pdb:5TJ8|rcsb pdb:5TJQ|rcsb pdb:6J1Z|rcsb pdb:6RSS|reactome:R-HSA-8948751|reactome:R-HSA-9013406|reactome:R-HSA-9013409|reactome:R-HSA-9013420|reactome:R-HSA-9013507	sgd:S000005912|refseq:NP_015030.3|dip:DIP-4047N|ensemblfungi:YOR385W(gene)|ensemblfungi:YOR385W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:Xj0Xssn75HP9sp/tHNe4n83eHPE9606	rogid:8SWTqlDNdzFcWIa8miL9cz87Peg559292	intact-crc:34A2200981AB8E54|rigid:GQDfiNCenB5G/dc71iclN6YSxhg	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P00492	uniprotkb:Q12056	intact:EBI-748210|uniprotkb:A6NHF0|uniprotkb:B2R8M9|ensembl:ENSP00000298556	intact:EBI-30488|uniprotkb:D6W2T0|ensemblfungi:YOR226C	psi-mi:hprt_human(display_long)|uniprotkb:HPRT1(gene name)|psi-mi:HPRT1(display_short)|uniprotkb:HPRT(gene name synonym)	psi-mi:isu2_yeast(display_long)|uniprotkb:Iron sulfur cluster scaffold protein 2(gene name synonym)|uniprotkb:ISU2(gene name)|psi-mi:ISU2(display_short)|uniprotkb:NUA2(gene name synonym)|uniprotkb:YOR226C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551060|imex:IM-24995-3336	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000185.1|ensembl:ENSG00000165704(gene)|ensembl:ENST00000298556(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001913"(T cell mediated cytotoxicity)|go:"GO:0001975"(response to amphetamine)|go:"GO:0004422"(hypoxanthine phosphoribosyltransferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006164"(purine nucleotide biosynthetic process)|go:"GO:0006166"(purine ribonucleoside salvage)|go:"GO:0006168"(adenine salvage)|go:"GO:0006178"(guanine salvage)|go:"GO:0007625"(grooming behavior)|go:"GO:0007626"(locomotory behavior)|go:"GO:0021756"(striatum development)|go:"GO:0021895"(cerebral cortex neuron differentiation)|go:"GO:0021954"(central nervous system neuron development)|go:"GO:0032263"(GMP salvage)|go:"GO:0032264"(IMP salvage)|go:"GO:0042417"(dopamine metabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043103"(hypoxanthine salvage)|go:"GO:0045964"(positive regulation of dopamine metabolic process)|go:"GO:0046038"(GMP catabolic process)|go:"GO:0046040"(IMP metabolic process)|go:"GO:0046100"(hypoxanthine metabolic process)|go:"GO:0046651"(lymphocyte proliferation)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0052657"(guanine phosphoribosyltransferase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000836(Phosphoribosyltransferase)|interpro:IPR005904(Hypoxanthine phosphoribosyl transferase)|interpro:IPR029057|mint:P00492|rcsb pdb:1BZY|rcsb pdb:1D6N|rcsb pdb:1HMP|rcsb pdb:1Z7G|go:"GO:0048813"(dendrite morphogenesis)|rcsb pdb:2VFA|rcsb pdb:3GEP|rcsb pdb:3GGC|rcsb pdb:3GGJ|rcsb pdb:4IJQ|rcsb pdb:4KN6|rcsb pdb:4RAB|rcsb pdb:4RAC|rcsb pdb:4RAD|rcsb pdb:4RAN|rcsb pdb:4RAO|rcsb pdb:4RAQ|rcsb pdb:5BRN|rcsb pdb:5BSK|rcsb pdb:5HIA|rcsb pdb:5W8V|rcsb pdb:6BNJ|reactome:R-HSA-74217	sgd:S000005752|refseq:NP_014869.3|dip:DIP-4123N|ensemblfungi:YOR226C(gene)|ensemblfungi:YOR226C_mRNA(transcript)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005737"(cytoplasm)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR002871(NIF system FeS cluster assembly, NifU, N-terminal)|interpro:IPR011339(ISC system FeS cluster assembly, IscU scaffold)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:w87Sv/qOAkHFqJm0vu0Ayqlz7TA9606	rogid:e4qx7ic8wpO6cTHGl73je/JVzMY559292	intact-crc:6EB9E6DD2668E2A6|rigid:Lpr9k6sEcTlx/vkByavYO7/5wLg	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q12056	uniprotkb:Q08379	intact:EBI-30488|uniprotkb:D6W2T0|ensemblfungi:YOR226C	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	psi-mi:isu2_yeast(display_long)|uniprotkb:Iron sulfur cluster scaffold protein 2(gene name synonym)|uniprotkb:ISU2(gene name)|psi-mi:ISU2(display_short)|uniprotkb:NUA2(gene name synonym)|uniprotkb:YOR226C(locus name)	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551056|imex:IM-24995-3335	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005752|refseq:NP_014869.3|dip:DIP-4123N|ensemblfungi:YOR226C(gene)|ensemblfungi:YOR226C_mRNA(transcript)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005737"(cytoplasm)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR002871(NIF system FeS cluster assembly, NifU, N-terminal)|interpro:IPR011339(ISC system FeS cluster assembly, IscU scaffold)	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2017/05/26	rogid:e4qx7ic8wpO6cTHGl73je/JVzMY559292	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	intact-crc:6468BD7675E1F038|rigid:s6Eve3irpeAd2PIjh9OxC3n5OJs	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q07951	uniprotkb:Q0VDD7	intact:EBI-31959|uniprotkb:D6VY23|ensemblfungi:YLR021W	intact:EBI-741210|ensembl:ENSP00000465822|ensembl:ENSP00000500215|uniprotkb:Q13411|uniprotkb:Q8N825|uniprotkb:Q96D63|uniprotkb:Q9BU49	psi-mi:poc3_yeast(display_long)|uniprotkb:POC3(gene name synonym)|uniprotkb:Increased recombination centers protein 25(gene name synonym)|uniprotkb:IRC25(gene name)|psi-mi:IRC25(display_short)|uniprotkb:DMP2(gene name synonym)|uniprotkb:YLR021W(locus name)	psi-mi:brme1_human(display_long)|uniprotkb:BRME1(gene name)|psi-mi:BRME1(display_short)|uniprotkb:C19orf57(gene name synonym)|uniprotkb:Pre-T/NK cell-associated protein 3B3(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551044|imex:IM-24995-3332	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013121.1|sgd:S000004011|dip:DIP-4747N|mint:Q07951|ensemblfungi:YLR021W(gene)|ensemblfungi:YLR021W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043248"(proteasome assembly)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|interpro:IPR018854|rcsb pdb:2Z5B|rcsb pdb:2Z5C	refseq:NP_077299.3|ensembl:ENSG00000132016(gene)|ensembl:ENSG00000288152(gene)|ensembl:ENST00000586783(transcript)|ensembl:ENST00000672170(transcript)|go:"GO:0005694"(chromosome)|go:"GO:0007144"(female meiosis I)|go:"GO:0007275"(multicellular organism development)|go:"GO:0007283"(spermatogenesis)|go:"GO:1990918"(double-strand break repair involved in meiotic recombination)|interpro:IPR031441|refseq:NP_001332773.1	-	crc64:6CA25E8ED0491EE2	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:5xcWnXqOt0DxQvelDvtc8ob2bj0559292	rogid:YUbAjs5ZmWOPWRA9kq5qRZRioR49606	intact-crc:445A2C3E29DE7623|rigid:35A6MX4dE+GvyRN0fhmWQM9BMAo	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q12020	uniprotkb:P63279	intact:EBI-38714|uniprotkb:D6VY82|ensemblfungi:YLR082C	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	psi-mi:srl2_yeast(display_long)|uniprotkb:Suppressor of RAD53 null lethality protein 2(gene name synonym)|uniprotkb:SRL2(gene name)|psi-mi:SRL2(display_short)|uniprotkb:YLR082C(locus name)	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551048|imex:IM-24995-3333	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000004072|refseq:NP_013183.1|mint:Q12020|dip:DIP-1442N|ensemblfungi:YLR082C(gene)|ensemblfungi:YLR082C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006139"(nucleobase-containing compound metabolic process)	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N	-	crc64:A39CD3D2E0F9BBF3	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:HVo/JUo9fmmcCD0iLScF47NCDrM559292	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	intact-crc:03054D805EF7C86F|rigid:T6PAbjXxLoUlyOa/YM67dr1sJg8	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O95751	uniprotkb:Q12055	intact:EBI-740738|ensembl:ENSP00000359557|uniprotkb:Q6IAR6	intact:EBI-22197|uniprotkb:D6VRI5|uniprotkb:E9P8W4|ensemblfungi:YDL166C	psi-mi:ldoc1_human(display_long)|uniprotkb:Leucine zipper protein down-regulated in cancer cells(gene name synonym)|uniprotkb:LDOC1(gene name)|psi-mi:LDOC1(display_short)|uniprotkb:BCUR1(gene name synonym)	psi-mi:kad6_yeast(display_long)|uniprotkb:FAP7(gene name)|psi-mi:FAP7(display_short)|uniprotkb:POS9-activating factor 7(gene name synonym)|uniprotkb:YDL166C(locus name)|uniprotkb:Dual activity adenylate kinase/ATPase(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551052|imex:IM-24995-3334	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_036449.1|ensembl:ENSG00000182195(gene)|ensembl:ENST00000370526(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071225"(cellular response to muramyl dipeptide)|interpro:IPR032549|interpro:IPR032567	refseq:NP_010115.1|sgd:S000002325|reactome:R-SCE-499943|dip:DIP-4793N|ensemblfungi:YDL166C(gene)|ensemblfungi:YDL166C_mRNA(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0004017"(adenylate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0034599"(cellular response to oxidative stress)|interpro:IPR020618|interpro:IPR027417	-	-	crc64:836A25B0D7E2633C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Ediu0oNiZ/+YVY8l3fNdgP5A+v09606	rogid:/hVE29n+kxI3CjMUlxtJxrvUpYk559292	intact-crc:B2E89C3A6E648D04|rigid:ekFS1249aT54NGZSYJuXfSriR8U	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O95994	uniprotkb:Q12140	intact:EBI-712648|ensembl:ENSP00000391490	intact:EBI-36401|uniprotkb:D6VRV7|ensemblfungi:YDL037C	psi-mi:agr2_human(display_long)|uniprotkb:Secreted cement gland protein XAG-2 homolog(gene name synonym)|uniprotkb:HPC8(gene name synonym)|uniprotkb:AG2(gene name synonym)|uniprotkb:UNQ515/PRO1030(orf name)|uniprotkb:AGR2(gene name)|psi-mi:AGR2(display_short)	psi-mi:bsc1_yeast(display_long)|uniprotkb:BSC1(gene name)|psi-mi:BSC1(display_short)|uniprotkb:D2734(orf name)|uniprotkb:YDL037C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551076|imex:IM-24995-3340	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005615"(extracellular space)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0042802"(identical protein binding)|go:"GO:0045742"(positive regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0048546"(digestive tract morphogenesis)|go:"GO:0048639"(positive regulation of developmental growth)|go:"GO:0060480"(lung goblet cell differentiation)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070254"(mucus secretion)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:1903896"(positive regulation of IRE1-mediated unfolded protein response)|go:"GO:1903899"(positive regulation of PERK-mediated unfolded protein response)|interpro:IPR036249|rcsb pdb:2LNS|rcsb pdb:2LNT|ensembl:ENSG00000106541(gene)|ensembl:ENST00000419304(transcript)|go:"GO:0002162"(dystroglycan binding)|go:"GO:0005154"(epidermal growth factor receptor binding)|refseq:NP_006399.1|refseq:XP_005249638.1|dip:DIP-48825N	sgd:S000002195|refseq:NP_010247.1|mint:Q12140|dip:DIP-5600N|ensemblfungi:YDL037C(gene)|ensemblfungi:YDL037C_mRNA(transcript)|interpro:IPR018789	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:E824a1MDXuGzk23ohjS7HAeEx5U9606	rogid:SmUACU6i/VlGLn/aQLehbLRAWjg559292	intact-crc:F0425ECC7CB28484|rigid:4FQbXEZpmcQEmuFAbCM/QPhhQOs	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q12083	uniprotkb:O14641	intact:EBI-31634|uniprotkb:D6W3K4|ensemblfungi:YPL164C	intact:EBI-740850|ensembl:ENSP00000005340|uniprotkb:Q53XM0|uniprotkb:D3DTN3	psi-mi:mlh3_yeast(display_long)|uniprotkb:MLH3(gene name)|psi-mi:MLH3(display_short)|uniprotkb:MutL protein homolog 3(gene name synonym)|uniprotkb:P2550(orf name)|uniprotkb:YPL164C(locus name)	psi-mi:dvl2_human(display_long)|uniprotkb:DSH homolog 2(gene name synonym)|uniprotkb:DVL2(gene name)|psi-mi:DVL2(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551064|imex:IM-24995-3337	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015161.1|sgd:S000006085|dip:DIP-2414N|ensemblfungi:YPL164C(gene)|ensemblfungi:YPL164C_mRNA(transcript)|go:"GO:0000710"(meiotic mismatch repair)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006298"(mismatch repair)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0030983"(mismatched DNA binding)|go:"GO:0032300"(mismatch repair complex)|go:"GO:0097587"(MutLgamma complex)|interpro:IPR013507(DNA mismatch repair protein, C-terminal)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR014790(MutL, C-terminal, dimerisation)|interpro:IPR020568|interpro:IPR028830|interpro:IPR036890|interpro:IPR037198|interpro:IPR038973|interpro:IPR042120|rcsb pdb:6RMN|rcsb pdb:6SHX|rcsb pdb:6SNS|rcsb pdb:6SNV	refseq:NP_004413.1|ensembl:ENSG00000004975(gene)|ensembl:ENST00000005340(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005109"(frizzled binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0007507"(heart development)|go:"GO:0016235"(aggresome)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044340"(canonical Wnt signaling pathway involved in regulation of cell proliferation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0150012"(positive regulation of neuron projection arborization)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008341(Dishevelled-2 region)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:O14641|rcsb pdb:2REY|rcsb pdb:3CBX|rcsb pdb:3CBY|rcsb pdb:3CBZ|rcsb pdb:3CC0|rcsb pdb:4WIP|rcsb pdb:5LNP|rcsb pdb:5SUY|rcsb pdb:5SUZ|rcsb pdb:6IW3|rcsb pdb:6JCK|reactome:R-HSA-201681|reactome:R-HSA-201688|reactome:R-HSA-2028269|reactome:R-HSA-4086400|reactome:R-HSA-4608870|reactome:R-HSA-4641258|reactome:R-HSA-4641262|reactome:R-HSA-5099900|reactome:R-HSA-5368598|reactome:R-HSA-5663220|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9673324|ensembl:ENSP00000005340|dip:DIP-34433N	-	crc64:970FD7F57EB6E3B1	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:g47/5yM9oWZ13CIZOZ7QT6A+LW0559292	rogid:2Vdc8oRnT4Mz/j+EXQXrL3AszOc9606	intact-crc:FB8DA70464615A87|rigid:16ES/w009LWem2L7ONdWO8+tzbA	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O95994	uniprotkb:Q12118	intact:EBI-712648|ensembl:ENSP00000391490	intact:EBI-31784|uniprotkb:D6W273|ensemblfungi:YOR007C	psi-mi:agr2_human(display_long)|uniprotkb:Secreted cement gland protein XAG-2 homolog(gene name synonym)|uniprotkb:HPC8(gene name synonym)|uniprotkb:AG2(gene name synonym)|uniprotkb:UNQ515/PRO1030(orf name)|uniprotkb:AGR2(gene name)|psi-mi:AGR2(display_short)	psi-mi:sgt2_yeast(display_long)|uniprotkb:Viral protein U-binding protein(gene name synonym)|uniprotkb:SGT/UBP(gene name synonym)|uniprotkb:SGT2(gene name)|psi-mi:SGT2(display_short)|uniprotkb:UNF346(orf name)|uniprotkb:YOR007C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551068|imex:IM-24995-3338	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005615"(extracellular space)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0042802"(identical protein binding)|go:"GO:0045742"(positive regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0048546"(digestive tract morphogenesis)|go:"GO:0048639"(positive regulation of developmental growth)|go:"GO:0060480"(lung goblet cell differentiation)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070254"(mucus secretion)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:1903896"(positive regulation of IRE1-mediated unfolded protein response)|go:"GO:1903899"(positive regulation of PERK-mediated unfolded protein response)|interpro:IPR036249|rcsb pdb:2LNS|rcsb pdb:2LNT|ensembl:ENSG00000106541(gene)|ensembl:ENST00000419304(transcript)|go:"GO:0002162"(dystroglycan binding)|go:"GO:0005154"(epidermal growth factor receptor binding)|refseq:NP_006399.1|refseq:XP_005249638.1|dip:DIP-48825N	refseq:NP_014649.1|sgd:S000005533|dip:DIP-1983N|mint:Q12118|ensemblfungi:YOR007C(gene)|ensemblfungi:YOR007C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0009408"(response to heat)|go:"GO:0016020"(membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0072380"(TRC complex)|go:"GO:1903646"(positive regulation of chaperone-mediated protein folding)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR032374|rcsb pdb:2LXB|rcsb pdb:2LXC|rcsb pdb:3ZDM|rcsb pdb:4ASV|rcsb pdb:4ASW|rcsb pdb:5LYN|rcsb pdb:5LYP|reactome:R-SCE-9609523	-	-	crc64:33539B74F742BD3C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:E824a1MDXuGzk23ohjS7HAeEx5U9606	rogid:u4qztYWJIAVQOzZGnkLFnO3S2NA559292	intact-crc:2174129F9A579B60|rigid:xaz+7kRyJHFYlSLNGF+ccJsj5sc	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q12134	uniprotkb:O14641	intact:EBI-37262|uniprotkb:D6W2Y2|ensemblfungi:YOR284W	intact:EBI-740850|ensembl:ENSP00000005340|uniprotkb:Q53XM0|uniprotkb:D3DTN3	psi-mi:hua2_yeast(display_long)|uniprotkb:HUA2(gene name)|psi-mi:HUA2(display_short)|uniprotkb:YOR284W(locus name)	psi-mi:dvl2_human(display_long)|uniprotkb:DSH homolog 2(gene name synonym)|uniprotkb:DVL2(gene name)|psi-mi:DVL2(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551072|imex:IM-24995-3339	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005810|refseq:NP_014927.3|dip:DIP-1472N|ensemblfungi:YOR284W(gene)|ensemblfungi:YOR284W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)	refseq:NP_004413.1|ensembl:ENSG00000004975(gene)|ensembl:ENST00000005340(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005109"(frizzled binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0007507"(heart development)|go:"GO:0016235"(aggresome)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044340"(canonical Wnt signaling pathway involved in regulation of cell proliferation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0150012"(positive regulation of neuron projection arborization)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008341(Dishevelled-2 region)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:O14641|rcsb pdb:2REY|rcsb pdb:3CBX|rcsb pdb:3CBY|rcsb pdb:3CBZ|rcsb pdb:3CC0|rcsb pdb:4WIP|rcsb pdb:5LNP|rcsb pdb:5SUY|rcsb pdb:5SUZ|rcsb pdb:6IW3|rcsb pdb:6JCK|reactome:R-HSA-201681|reactome:R-HSA-201688|reactome:R-HSA-2028269|reactome:R-HSA-4086400|reactome:R-HSA-4608870|reactome:R-HSA-4641258|reactome:R-HSA-4641262|reactome:R-HSA-5099900|reactome:R-HSA-5368598|reactome:R-HSA-5663220|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9673324|ensembl:ENSP00000005340|dip:DIP-34433N	-	crc64:B1F3A81B7C0F65AC	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:1pZZ+nqYY1Ah7Zdeu4QP4kvKfsw559292	rogid:2Vdc8oRnT4Mz/j+EXQXrL3AszOc9606	intact-crc:36673AA2EE07696E|rigid:5PUN737MJ7ucAP8Bhs3yLOLJQ6M	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q12161	uniprotkb:E9PFK9	intact:EBI-34372|uniprotkb:D6W213|ensemblfungi:YOL054W	intact:EBI-11523104|ensembl:ENSP00000403429	psi-mi:psh1_yeast(display_long)|uniprotkb:PSH1(gene name)|psi-mi:PSH1(display_short)|uniprotkb:POB3/SPT16 histone-associated protein 1(gene name synonym)|uniprotkb:O1263(orf name)|uniprotkb:YOL054W(locus name)	psi-mi:e9pfk9_human(display_long)|uniprotkb:RABGEF1(gene name)|psi-mi:RABGEF1(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551096|imex:IM-24995-3345	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014587.1|sgd:S000005415|mint:Q12161|dip:DIP-6481N|ensemblfungi:YOL054W(gene)|ensemblfungi:YOL054W_mRNA(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907	ensembl:ENSG00000154710(gene)|ensembl:ENST00000439720(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|interpro:IPR002653(Zinc finger, A20-type)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR037191|interpro:IPR041545	-	crc64:CE0ECBCB6D465554	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:AvPMRd/GjfaTyQjEfMPhBVcvOs4559292	rogid:JDHW8cuCB2z39j6a+LlkARnLfYo9606	intact-crc:680E2D126CFD21BE|rigid:TsRHWiVq3l/wIp27zh63pFUpDhc	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O95994	uniprotkb:Q12154	intact:EBI-712648|ensembl:ENSP00000391490	intact:EBI-2989|uniprotkb:Q6B1B6|uniprotkb:D6VRQ0|ensemblfungi:YDL100C	psi-mi:agr2_human(display_long)|uniprotkb:Secreted cement gland protein XAG-2 homolog(gene name synonym)|uniprotkb:HPC8(gene name synonym)|uniprotkb:AG2(gene name synonym)|uniprotkb:UNQ515/PRO1030(orf name)|uniprotkb:AGR2(gene name)|psi-mi:AGR2(display_short)	psi-mi:get3_yeast(display_long)|uniprotkb:YDL100C(locus name)|uniprotkb:GET3(gene name)|psi-mi:GET3(display_short)|uniprotkb:ARR4(gene name synonym)|uniprotkb:D2371(orf name)|uniprotkb:Arsenical pump-driving ATPase(gene name synonym)|uniprotkb:Arsenite-stimulated ATPase(gene name synonym)|uniprotkb:Guided entry of tail-anchored proteins 3(gene name synonym)|uniprotkb:Golgi to ER traffic protein 3(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551092|imex:IM-24995-3344	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005615"(extracellular space)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0042802"(identical protein binding)|go:"GO:0045742"(positive regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0048546"(digestive tract morphogenesis)|go:"GO:0048639"(positive regulation of developmental growth)|go:"GO:0060480"(lung goblet cell differentiation)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070254"(mucus secretion)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:1903896"(positive regulation of IRE1-mediated unfolded protein response)|go:"GO:1903899"(positive regulation of PERK-mediated unfolded protein response)|interpro:IPR036249|rcsb pdb:2LNS|rcsb pdb:2LNT|ensembl:ENSG00000106541(gene)|ensembl:ENST00000419304(transcript)|go:"GO:0002162"(dystroglycan binding)|go:"GO:0005154"(epidermal growth factor receptor binding)|refseq:NP_006399.1|refseq:XP_005249638.1|dip:DIP-48825N	refseq:NP_010183.1|sgd:S000002258|dip:DIP-3908N|mint:Q12154|ensemblfungi:YDL100C(gene)|ensemblfungi:YDL100C_mRNA(transcript)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0009408"(response to heat)|go:"GO:0010038"(response to metal ion)|go:"GO:0016787"(hydrolase activity)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043529"(GET complex)|go:"GO:0045048"(protein insertion into ER membrane)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0046872"(metal ion binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:1990507"(obsolete ATP-independent chaperone mediated protein folding)|interpro:IPR016300(Arsenite-transporting ATPase)|interpro:IPR025723|interpro:IPR027417|interpro:IPR027542|rcsb pdb:2WOJ|rcsb pdb:3A36|rcsb pdb:3A37|rcsb pdb:3B2E|rcsb pdb:3H84|rcsb pdb:3IDQ|rcsb pdb:3SJA|rcsb pdb:3SJB|rcsb pdb:3SJC|rcsb pdb:3SJD|rcsb pdb:3VLC|rcsb pdb:3ZS8|rcsb pdb:3ZS9|rcsb pdb:4PWX|rcsb pdb:4XTR|rcsb pdb:4XVU|rcsb pdb:4XWO|rcsb pdb:5BW8|rcsb pdb:5BWK	-	-	crc64:F795C359B5A4A461	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:E824a1MDXuGzk23ohjS7HAeEx5U9606	rogid:Y+PTDg+beVeCH5mn4BvWi5wBP4A559292	intact-crc:C36978BAFFC08D9C|rigid:hXSL9mu7GabI1rRK2Hhhykh85Mw	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O15294-3	uniprotkb:Q12140	intact:EBI-11536584|ensembl:ENSP00000362805	intact:EBI-36401|uniprotkb:D6VRV7|ensemblfungi:YDL037C	psi-mi:o15294-3(display_long)|uniprotkb:O-GlcNAc transferase subunit p110(gene name synonym)|uniprotkb:O-linked N-acetylglucosamine transferase 110 kDa subunit(gene name synonym)|uniprotkb:OGT(gene name)|psi-mi:OGT(display_short)	psi-mi:bsc1_yeast(display_long)|uniprotkb:BSC1(gene name)|psi-mi:BSC1(display_short)|uniprotkb:D2734(orf name)|uniprotkb:YDL037C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551080|imex:IM-24995-3341	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000147162(gene)|ensembl:ENST00000373701(transcript)|intact:EBI-539828(isoform-parent)|uniprotkb:O15294-3(isoform-parent)	sgd:S000002195|refseq:NP_010247.1|mint:Q12140|dip:DIP-5600N|ensemblfungi:YDL037C(gene)|ensemblfungi:YDL037C_mRNA(transcript)|interpro:IPR018789	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:tD46KhQ2nrCEOBxms28dL2gQjFQ9606	rogid:SmUACU6i/VlGLn/aQLehbLRAWjg559292	intact-crc:A0362CBCBA728395|rigid:4/hnLIUJAiygqxxyJvMKyADo424	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O43852-3	uniprotkb:Q12154	intact:EBI-11536607|ensembl:ENSP00000420381	intact:EBI-2989|uniprotkb:Q6B1B6|uniprotkb:D6VRQ0|ensemblfungi:YDL100C	psi-mi:o43852-3(display_long)|uniprotkb:CALU(gene name)|psi-mi:CALU(display_short)|uniprotkb:Crocalbin(gene name synonym)|uniprotkb:IEF SSP 9302(gene name synonym)	psi-mi:get3_yeast(display_long)|uniprotkb:YDL100C(locus name)|uniprotkb:GET3(gene name)|psi-mi:GET3(display_short)|uniprotkb:ARR4(gene name synonym)|uniprotkb:D2371(orf name)|uniprotkb:Arsenical pump-driving ATPase(gene name synonym)|uniprotkb:Arsenite-stimulated ATPase(gene name synonym)|uniprotkb:Guided entry of tail-anchored proteins 3(gene name synonym)|uniprotkb:Golgi to ER traffic protein 3(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551084|imex:IM-24995-3342	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-1171069(isoform-parent)|ensembl:ENSG00000128595(gene)|ensembl:ENST00000479257(transcript)|uniprotkb:O43852-3(isoform-parent)	refseq:NP_010183.1|sgd:S000002258|dip:DIP-3908N|mint:Q12154|ensemblfungi:YDL100C(gene)|ensemblfungi:YDL100C_mRNA(transcript)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0009408"(response to heat)|go:"GO:0010038"(response to metal ion)|go:"GO:0016787"(hydrolase activity)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043529"(GET complex)|go:"GO:0045048"(protein insertion into ER membrane)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0046872"(metal ion binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:1990507"(obsolete ATP-independent chaperone mediated protein folding)|interpro:IPR016300(Arsenite-transporting ATPase)|interpro:IPR025723|interpro:IPR027417|interpro:IPR027542|rcsb pdb:2WOJ|rcsb pdb:3A36|rcsb pdb:3A37|rcsb pdb:3B2E|rcsb pdb:3H84|rcsb pdb:3IDQ|rcsb pdb:3SJA|rcsb pdb:3SJB|rcsb pdb:3SJC|rcsb pdb:3SJD|rcsb pdb:3VLC|rcsb pdb:3ZS8|rcsb pdb:3ZS9|rcsb pdb:4PWX|rcsb pdb:4XTR|rcsb pdb:4XVU|rcsb pdb:4XWO|rcsb pdb:5BW8|rcsb pdb:5BWK	-	-	crc64:F795C359B5A4A461	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:aOndJVrdQPKMOgVAthD1hiWG67I9606	rogid:Y+PTDg+beVeCH5mn4BvWi5wBP4A559292	intact-crc:840D277B8057FF74|rigid:GvPIIbD+WC8wfweB85M2uc9EhGA	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O95967	uniprotkb:Q12154	intact:EBI-743414|uniprotkb:O75967|uniprotkb:A8K7R4|uniprotkb:B3KM31|uniprotkb:B3KQT1|ensembl:ENSP00000309953|ensembl:ENSP00000435295	intact:EBI-2989|uniprotkb:Q6B1B6|uniprotkb:D6VRQ0|ensemblfungi:YDL100C	psi-mi:fbln4_human(display_long)|uniprotkb:Fibulin-4(gene name synonym)|uniprotkb:Protein UPH1(gene name synonym)|uniprotkb:EFEMP2(gene name)|psi-mi:EFEMP2(display_short)|uniprotkb:FBLN4(gene name synonym)|uniprotkb:UNQ200/PRO226(orf name)	psi-mi:get3_yeast(display_long)|uniprotkb:YDL100C(locus name)|uniprotkb:GET3(gene name)|psi-mi:GET3(display_short)|uniprotkb:ARR4(gene name synonym)|uniprotkb:D2371(orf name)|uniprotkb:Arsenical pump-driving ATPase(gene name synonym)|uniprotkb:Arsenite-stimulated ATPase(gene name synonym)|uniprotkb:Guided entry of tail-anchored proteins 3(gene name synonym)|uniprotkb:Golgi to ER traffic protein 3(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551088|imex:IM-24995-3343	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_058634.4|ensembl:ENSG00000172638(gene)|ensembl:ENST00000307998(transcript)|ensembl:ENST00000531972(transcript)|go:"GO:0001527"(microfibril)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0008201"(heparin binding)|go:"GO:0031012"(extracellular matrix)|go:"GO:0035904"(aorta development)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0048251"(elastic fiber assembly)|go:"GO:0060414"(aorta smooth muscle tissue morphogenesis)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071953"(elastic fiber)|go:"GO:0097084"(vascular associated smooth muscle cell development)|go:"GO:1903561"(extracellular vesicle)|go:"GO:1904026"(regulation of collagen fibril organization)|go:"GO:1904028"(positive regulation of collagen fibril organization)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1904831"(positive regulation of aortic smooth muscle cell differentiation)|go:"GO:1905609"(positive regulation of smooth muscle cell-matrix adhesion)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR018097|interpro:IPR026823|interpro:IPR026824|mint:O95967|rcsb pdb:2KL7|reactome:R-HSA-2129379|dip:DIP-34518N	refseq:NP_010183.1|sgd:S000002258|dip:DIP-3908N|mint:Q12154|ensemblfungi:YDL100C(gene)|ensemblfungi:YDL100C_mRNA(transcript)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0009408"(response to heat)|go:"GO:0010038"(response to metal ion)|go:"GO:0016787"(hydrolase activity)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043529"(GET complex)|go:"GO:0045048"(protein insertion into ER membrane)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0046872"(metal ion binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:1990507"(obsolete ATP-independent chaperone mediated protein folding)|interpro:IPR016300(Arsenite-transporting ATPase)|interpro:IPR025723|interpro:IPR027417|interpro:IPR027542|rcsb pdb:2WOJ|rcsb pdb:3A36|rcsb pdb:3A37|rcsb pdb:3B2E|rcsb pdb:3H84|rcsb pdb:3IDQ|rcsb pdb:3SJA|rcsb pdb:3SJB|rcsb pdb:3SJC|rcsb pdb:3SJD|rcsb pdb:3VLC|rcsb pdb:3ZS8|rcsb pdb:3ZS9|rcsb pdb:4PWX|rcsb pdb:4XTR|rcsb pdb:4XVU|rcsb pdb:4XWO|rcsb pdb:5BW8|rcsb pdb:5BWK	-	-	crc64:F795C359B5A4A461	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:L8jMp8rFYb6DRRusfWgyd9zN2KI9606	rogid:Y+PTDg+beVeCH5mn4BvWi5wBP4A559292	intact-crc:62B62395A28BB521|rigid:/akFsFjlNJyDpjpxsyG/tWm3cig	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P48775	uniprotkb:Q12181	intact:EBI-743494|ensembl:ENSP00000444788|ensembl:ENSP00000460086|uniprotkb:A8K053	intact:EBI-37624|uniprotkb:D6W456|ensemblfungi:YPR048W	psi-mi:t23o_human(display_long)|uniprotkb:Tryptophan pyrrolase(gene name synonym)|uniprotkb:Tryptophan oxygenase(gene name synonym)|uniprotkb:Tryptamin 2,3-dioxygenase(gene name synonym)|uniprotkb:TDO2(gene name)|psi-mi:TDO2(display_short)|uniprotkb:TDO(gene name synonym)|uniprotkb:Tryptophanase(gene name synonym)	psi-mi:ndor1_yeast(display_long)|uniprotkb:TAH18(gene name)|psi-mi:TAH18(display_short)|uniprotkb:NADPH-dependent FMN and FAD-containing oxidoreductase(gene name synonym)|uniprotkb:YP9499.06(orf name)|uniprotkb:YPR048W(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551116|imex:IM-24995-3350	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000151790(gene)|ensembl:ENSG00000262635(gene)|ensembl:ENST00000536354(transcript)|ensembl:ENST00000573403(transcript)|go:"GO:0004833"(tryptophan 2,3-dioxygenase activity)|go:"GO:0005829"(cytosol)|go:"GO:0016597"(amino acid binding)|go:"GO:0019441"(tryptophan catabolic process to kynurenine)|go:"GO:0019442"(tryptophan catabolic process to acetyl-CoA)|go:"GO:0019825"(oxygen binding)|go:"GO:0020037"(heme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051289"(protein homotetramerization)|go:"GO:1904842"(response to nitroglycerin)|interpro:IPR004981(Tryptophan 2,3-dioxygenase)|interpro:IPR037217|mint:P48775|rcsb pdb:4PW8|rcsb pdb:5TI9|rcsb pdb:5TIA|rcsb pdb:6A4I|rcsb pdb:6PYY|rcsb pdb:6PYZ|rcsb pdb:6UD5|rcsb pdb:6VBN|reactome:R-HSA-71240|refseq:NP_005642.1	refseq:NP_015373.1|sgd:S000006252|dip:DIP-1688N|mint:Q12181|ensemblfungi:YPR048W(gene)|ensemblfungi:YPR048W_mRNA(transcript)|go:"GO:0003958"(NADPH-hemoprotein reductase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006809"(nitric oxide biosynthetic process)|go:"GO:0010181"(FMN binding)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0016651"("oxidoreductase activity, acting on NAD(P)H")|go:"GO:0016709"("oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen")|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0050660"(flavin adenine dinucleotide binding)|go:"GO:0050661"(NADP binding)|go:"GO:1901300"(positive regulation of hydrogen peroxide-mediated programmed cell death)|interpro:IPR001094(Flavodoxin-like)|interpro:IPR001433("Oxidoreductase FAD/NAD(P)-binding")|interpro:IPR001709(Flavoprotein pyridine nucleotide cytochrome reductase)|interpro:IPR003097(FAD-binding, type 1)|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|interpro:IPR017927|interpro:IPR017938|interpro:IPR023173|interpro:IPR028879|interpro:IPR029039|interpro:IPR039261	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:S+cyc710I52nIFQWgKhXFul9QZw9606	rogid:rMyciB2K1QEFDXSgbMznNQ811ko559292	intact-crc:50DD4D949804253C|rigid:1u/mvEqDXQHhIKCOK6b8SxQgzxs	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8N5R6	uniprotkb:Q12161	intact:EBI-740841|intact:EBI-953781|uniprotkb:B3KQ49|uniprotkb:A8K3U4|uniprotkb:A8MPQ6|uniprotkb:A8MV61|uniprotkb:A8MVU9|uniprotkb:Q9H5Q6|uniprotkb:Q8TAX6|intact:EBI-2320546|intact:EBI-11522976	intact:EBI-34372|uniprotkb:D6W213|ensemblfungi:YOL054W	psi-mi:ccd33_human(display_long)|uniprotkb:CCDC33(gene name)|psi-mi:CCDC33(display_short)|uniprotkb:Cancer/testis antigen 61(gene name synonym)	psi-mi:psh1_yeast(display_long)|uniprotkb:PSH1(gene name)|psi-mi:PSH1(display_short)|uniprotkb:POB3/SPT16 histone-associated protein 1(gene name synonym)|uniprotkb:O1263(orf name)|uniprotkb:YOL054W(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551112|imex:IM-24995-3349	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_079331.3|interpro:IPR000008(C2 calcium-dependent membrane targeting)|go:"GO:0005777"(peroxisome)|refseq:NP_001274110.1|refseq:NP_877592.2|mint:Q8N5R6|interpro:IPR035892|interpro:IPR039889	refseq:NP_014587.1|sgd:S000005415|mint:Q12161|dip:DIP-6481N|ensemblfungi:YOL054W(gene)|ensemblfungi:YOL054W_mRNA(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907	-	-	crc64:CE0ECBCB6D465554	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2021/11/30	rogid:eEIn7pQyfdHWx8TeLJpYy0i/gww9606	rogid:AvPMRd/GjfaTyQjEfMPhBVcvOs4559292	intact-crc:2EA798C80AEE5582|rigid:aXopAJOgoLUSDTx6zmifwQ79GHA	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q12161	uniprotkb:P15622-3	intact:EBI-34372|uniprotkb:D6W213|ensemblfungi:YOL054W	intact:EBI-10177272|ensembl:ENSP00000393442	psi-mi:psh1_yeast(display_long)|uniprotkb:PSH1(gene name)|psi-mi:PSH1(display_short)|uniprotkb:POB3/SPT16 histone-associated protein 1(gene name synonym)|uniprotkb:O1263(orf name)|uniprotkb:YOL054W(locus name)	psi-mi:p15622-3(display_long)|uniprotkb:ZNF647(gene name synonym)|uniprotkb:Zinc finger protein 647(gene name synonym)|uniprotkb:ZNF250(gene name)|psi-mi:ZNF250(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551100|imex:IM-24995-3346	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014587.1|sgd:S000005415|mint:Q12161|dip:DIP-6481N|ensemblfungi:YOL054W(gene)|ensemblfungi:YOL054W_mRNA(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907	ensembl:ENSG00000196150(gene)|ensembl:ENST00000417550(transcript)|intact:EBI-739678(isoform-parent)|uniprotkb:P15622-3(isoform-parent)	-	crc64:CE0ECBCB6D465554	isoform-comment:No experimental confirmation available.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:AvPMRd/GjfaTyQjEfMPhBVcvOs4559292	rogid:4AVjeOREEATULMJWtdeZt7rhi889606	intact-crc:7BD1C7813FF6788B|rigid:yRJou5+PcnSKbx49lLrit7cH2y0	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q12161	uniprotkb:P38432	intact:EBI-34372|uniprotkb:D6W213|ensemblfungi:YOL054W	intact:EBI-945751|uniprotkb:B2R931|ensembl:ENSP00000240316	psi-mi:psh1_yeast(display_long)|uniprotkb:PSH1(gene name)|psi-mi:PSH1(display_short)|uniprotkb:POB3/SPT16 histone-associated protein 1(gene name synonym)|uniprotkb:O1263(orf name)|uniprotkb:YOL054W(locus name)	psi-mi:coil_human(display_long)|uniprotkb:COIL(gene name)|psi-mi:COIL(display_short)|uniprotkb:CLN80(gene name synonym)|uniprotkb:p80-coilin(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551104|imex:IM-24995-3347	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014587.1|sgd:S000005415|mint:Q12161|dip:DIP-6481N|ensemblfungi:YOL054W(gene)|ensemblfungi:YOL054W_mRNA(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907	refseq:NP_004636.1|dip:DIP-38503N|ensembl:ENSG00000121058(gene)|ensembl:ENST00000240316(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0015030"(Cajal body)|go:"GO:0016020"(membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0030619"(U1 snRNA binding)|go:"GO:0030620"(U2 snRNA binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR024822|interpro:IPR031722|mint:P38432	-	crc64:CE0ECBCB6D465554	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:AvPMRd/GjfaTyQjEfMPhBVcvOs4559292	rogid:hd5p6AbyA/GYNEeca99Mdb41qM09606	intact-crc:C84714A59ECAA9D0|rigid:i3wOX+p5AKSKep1XoOjc9ScJKf8	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q12161	uniprotkb:P23511-2	intact:EBI-34372|uniprotkb:D6W213|ensemblfungi:YOL054W	intact:EBI-11061759|ensembl:ENSP00000229418	psi-mi:psh1_yeast(display_long)|uniprotkb:PSH1(gene name)|psi-mi:PSH1(display_short)|uniprotkb:POB3/SPT16 histone-associated protein 1(gene name synonym)|uniprotkb:O1263(orf name)|uniprotkb:YOL054W(locus name)	psi-mi:p23511-2(display_long)|uniprotkb:NFYA(gene name)|psi-mi:NFYA(display_short)|uniprotkb:CAAT box DNA-binding protein subunit A(gene name synonym)|uniprotkb:Nuclear transcription factor Y subunit A(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551108|imex:IM-24995-3348	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014587.1|sgd:S000005415|mint:Q12161|dip:DIP-6481N|ensemblfungi:YOL054W(gene)|ensemblfungi:YOL054W_mRNA(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907	intact:EBI-389739(isoform-parent)|ensembl:ENSG00000001167(gene)|ensembl:ENST00000353205(transcript)|uniprotkb:P23511-2(isoform-parent)	-	crc64:CE0ECBCB6D465554	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:AvPMRd/GjfaTyQjEfMPhBVcvOs4559292	rogid:9IOUoaGszX6kd9hzrCj6BBkgJ+09606	intact-crc:9F95558166E38345|rigid:DUrLoLDtg9vUEdl/j7cl4a61p34	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q12259	uniprotkb:P35520	intact:EBI-30776|uniprotkb:D6VYA8|ensemblfungi:YLR108C	intact:EBI-740135|uniprotkb:Q99425|uniprotkb:Q9BWC5|uniprotkb:B2R993|uniprotkb:D3DSK4|intact:EBI-14245939|ensembl:ENSP00000344460|ensembl:ENSP00000352643|ensembl:ENSP00000381225|ensembl:ENSP00000381231	psi-mi:yl108_yeast(display_long)|uniprotkb:L2913(orf name)|uniprotkb:YLR108C(locus name)	psi-mi:cbs_human(display_long)|uniprotkb:CBS(gene name)|psi-mi:CBS(display_short)|uniprotkb:Serine sulfhydrase(gene name synonym)|uniprotkb:Beta-thionase(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551136|imex:IM-24995-3355	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013209.1|sgd:S000004098|dip:DIP-4075N|ensemblfungi:YLR108C(gene)|ensemblfungi:YLR108C_mRNA(transcript)|go:"GO:0005634"(nucleus)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)	refseq:NP_000062.1|refseq:NP_001171479.1|refseq:NP_001171480.1|ensembl:ENSG00000160200(gene)|ensembl:ENST00000352178(transcript)|ensembl:ENST00000359624(transcript)|ensembl:ENST00000398158(transcript)|go:"GO:0004122"(cystathionine beta-synthase activity)|ensembl:ENST00000398165(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006535"(cysteine biosynthetic process from serine)|go:"GO:0006563"(L-serine metabolic process)|go:"GO:0006565"(L-serine catabolic process)|go:"GO:0019343"(cysteine biosynthetic process via cystathionine)|go:"GO:0019344"(cysteine biosynthetic process)|go:"GO:0019346"(transsulfuration)|go:"GO:0019448"(L-cysteine catabolic process)|go:"GO:0019825"(oxygen binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0020037"(heme binding)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042262"(DNA protection)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043418"(homocysteine catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0050421"("nitrite reductase (NO-forming) activity")|go:"GO:0050667"(homocysteine metabolic process)|go:"GO:0070025"(carbon monoxide binding)|go:"GO:0070026"(nitric oxide binding)|go:"GO:0070814"(hydrogen sulfide biosynthetic process)|go:"GO:0072341"(modified amino acid binding)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR001216(Cysteine synthase/cystathionine beta-synthase P-phosphate-binding site)|interpro:IPR001926(Pyridoxal phosphate-dependent enzyme, beta subunit)|interpro:IPR005857(Cystathionine beta-synthase)|interpro:IPR036052|mint:P35520|rcsb pdb:1JBQ|rcsb pdb:1M54|rcsb pdb:4COO|rcsb pdb:4L0D|rcsb pdb:4L27|rcsb pdb:4L28|rcsb pdb:4L3V|rcsb pdb:4PCU|rcsb pdb:4UUU|rcsb pdb:5MMS|reactome:R-HSA-1614603|reactome:R-HSA-2408508|refseq:XP_011528079.1|refseq:XP_011528083.1|refseq:XP_011528084.1|refseq:XP_011544396.1|refseq:XP_011544397.1|refseq:XP_011544399.1|refseq:XP_011544400.1|refseq:XP_011544401.1|refseq:NP_001307227.1|refseq:NP_001308002.1|refseq:XP_016883700.1|refseq:XP_016883701.1|refseq:XP_016883702.1|refseq:XP_016883703.1|refseq:XP_016883704.1|refseq:XP_016883705.1|refseq:XP_016883706.1|refseq:XP_016883707.1|refseq:XP_016883978.1|refseq:XP_016883979.1|refseq:XP_016883980.1|refseq:XP_016883981.1	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:CzknxXhhvgMp3J0/oi197EgZ05U559292	rogid:f9eo0cPOHppVY7Nqejag3YyK18s9606	intact-crc:51454C9C1EAAFB06|rigid:ewRxuzMo9umkg0gOnUIdBicjMrw	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q12211	uniprotkb:P35606	intact:EBI-14272|uniprotkb:D6W3F8|ensemblfungi:YPL212C	intact:EBI-1056534|uniprotkb:B4DZI8|intact:EBI-11019844|ensembl:ENSP00000329419	psi-mi:pus1_yeast(display_long)|uniprotkb:YPL212C(locus name)|uniprotkb:tRNA-uridine isomerase 1(gene name synonym)|uniprotkb:PUS1(gene name)|psi-mi:PUS1(display_short)|uniprotkb:tRNA pseudouridylate synthase 1(gene name synonym)	psi-mi:copb2_human(display_long)|uniprotkb:COPB2(gene name)|psi-mi:COPB2(display_short)|uniprotkb:Beta'-coat protein(gene name synonym)|uniprotkb:p102(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551132|imex:IM-24995-3354	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015112.1|sgd:S000006133|ensemblfungi:YPL212C(gene)|ensemblfungi:YPL212C_mRNA(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006400"(tRNA modification)|go:"GO:0009982"(pseudouridine synthase activity)|go:"GO:0031120"(snRNA pseudouridine synthesis)|go:"GO:1990481"(mRNA pseudouridine synthesis)|interpro:IPR001406(tRNA pseudouridine synthase)|interpro:IPR020094|go:"GO:0031119"(tRNA pseudouridine synthesis)|interpro:IPR020097|interpro:IPR020103|interpro:IPR041708|mint:Q12211|dip:DIP-5344N	refseq:NP_004757.1|ensembl:ENSG00000184432(gene)|ensembl:ENST00000333188(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0030133"(transport vesicle)|go:"GO:1901998"(toxin transport)|interpro:IPR001680(WD40 repeat)|interpro:IPR006692(Coatomer, WD associated region)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016453(Coatomer, beta' subunit)|interpro:IPR020472|interpro:IPR036322|mint:P35606|reactome:R-HSA-6807878|reactome:R-HSA-6811434|refseq:XP_016863001.1|dip:DIP-27603N	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:u8LVhy6qxRakYcjrKYN0QGn34iM559292	rogid:zkd7lOeV+OvHglnAJg6cXoMhgbg9606	intact-crc:C777B4DF3C86A628|rigid:h57e73cZRMo6xEO7IjDBkBDTFCc	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q12181	uniprotkb:O14641	intact:EBI-37624|uniprotkb:D6W456|ensemblfungi:YPR048W	intact:EBI-740850|ensembl:ENSP00000005340|uniprotkb:Q53XM0|uniprotkb:D3DTN3	psi-mi:ndor1_yeast(display_long)|uniprotkb:TAH18(gene name)|psi-mi:TAH18(display_short)|uniprotkb:NADPH-dependent FMN and FAD-containing oxidoreductase(gene name synonym)|uniprotkb:YP9499.06(orf name)|uniprotkb:YPR048W(locus name)	psi-mi:dvl2_human(display_long)|uniprotkb:DSH homolog 2(gene name synonym)|uniprotkb:DVL2(gene name)|psi-mi:DVL2(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551120|imex:IM-24995-3351	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015373.1|sgd:S000006252|dip:DIP-1688N|mint:Q12181|ensemblfungi:YPR048W(gene)|ensemblfungi:YPR048W_mRNA(transcript)|go:"GO:0003958"(NADPH-hemoprotein reductase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006809"(nitric oxide biosynthetic process)|go:"GO:0010181"(FMN binding)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0016651"("oxidoreductase activity, acting on NAD(P)H")|go:"GO:0016709"("oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen")|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0050660"(flavin adenine dinucleotide binding)|go:"GO:0050661"(NADP binding)|go:"GO:1901300"(positive regulation of hydrogen peroxide-mediated programmed cell death)|interpro:IPR001094(Flavodoxin-like)|interpro:IPR001433("Oxidoreductase FAD/NAD(P)-binding")|interpro:IPR001709(Flavoprotein pyridine nucleotide cytochrome reductase)|interpro:IPR003097(FAD-binding, type 1)|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|interpro:IPR017927|interpro:IPR017938|interpro:IPR023173|interpro:IPR028879|interpro:IPR029039|interpro:IPR039261	refseq:NP_004413.1|ensembl:ENSG00000004975(gene)|ensembl:ENST00000005340(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005109"(frizzled binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0007507"(heart development)|go:"GO:0016235"(aggresome)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044340"(canonical Wnt signaling pathway involved in regulation of cell proliferation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0150012"(positive regulation of neuron projection arborization)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008341(Dishevelled-2 region)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:O14641|rcsb pdb:2REY|rcsb pdb:3CBX|rcsb pdb:3CBY|rcsb pdb:3CBZ|rcsb pdb:3CC0|rcsb pdb:4WIP|rcsb pdb:5LNP|rcsb pdb:5SUY|rcsb pdb:5SUZ|rcsb pdb:6IW3|rcsb pdb:6JCK|reactome:R-HSA-201681|reactome:R-HSA-201688|reactome:R-HSA-2028269|reactome:R-HSA-4086400|reactome:R-HSA-4608870|reactome:R-HSA-4641258|reactome:R-HSA-4641262|reactome:R-HSA-5099900|reactome:R-HSA-5368598|reactome:R-HSA-5663220|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9673324|ensembl:ENSP00000005340|dip:DIP-34433N	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:rMyciB2K1QEFDXSgbMznNQ811ko559292	rogid:2Vdc8oRnT4Mz/j+EXQXrL3AszOc9606	intact-crc:6E4D9946BF15524F|rigid:iqBO894eW/Epd9Iqd6bwnrTVipU	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P63279	uniprotkb:Q12206	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	intact:EBI-20571|uniprotkb:D6W2T3|ensemblfungi:YOR229W	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:wtm2_yeast(display_long)|uniprotkb:WTM2(gene name)|psi-mi:WTM2(display_short)|uniprotkb:YOR50-19(orf name)|uniprotkb:YOR229W(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551124|imex:IM-24995-3352	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N	refseq:NP_014872.1|sgd:S000005755|ensemblfungi:YOR229W(gene)|ensemblfungi:YOR229W_mRNA(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010674"(negative regulation of transcription from RNA polymerase II promoter involved in meiotic cell cycle)|go:"GO:0031939"(obsolete negative regulation of chromatin silencing at telomere)|go:"GO:0034629"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061186"(negative regulation of silent mating-type cassette heterochromatin assembly)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|reactome:R-SCE-3214815|reactome:R-SCE-3214847|reactome:R-SCE-3214858|dip:DIP-1534N|mint:Q12206	-	-	crc64:4A8F5F879B88AA94	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	rogid:DCudPHib/PxB5+S+RRONJQyC+QI559292	intact-crc:589ACC7664283B6E|rigid:H3X0HgaZER9jaXMMANTE6+zp2Xg	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O95198	uniprotkb:Q12208	intact:EBI-746999|uniprotkb:B2RD18|uniprotkb:Q8N484|uniprotkb:Q8TBH5|uniprotkb:A6NCM7|uniprotkb:B4DFH7|uniprotkb:F5H6M3|ensembl:ENSP00000226725	intact:EBI-31589|uniprotkb:D6VYC7|ensemblfungi:YLR132C	psi-mi:klhl2_human(display_long)|uniprotkb:Actin-binding protein Mayven(gene name synonym)|uniprotkb:KLHL2(gene name)|psi-mi:KLHL2(display_short)	psi-mi:usb1_yeast(display_long)|uniprotkb:USB1(gene name)|psi-mi:USB1(display_short)|uniprotkb:U six biogenesis protein 1(gene name synonym)|uniprotkb:L3127(orf name)|uniprotkb:YLR132C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551128|imex:IM-24995-3353	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001154993.1|refseq:NP_001154994.1|refseq:NP_009177.3|refseq:NP_001317952.1|refseq:NP_001317953.1|refseq:XP_016863165.1|ensembl:ENSG00000109466(gene)|ensembl:ENST00000226725(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030027"(lamellipodium)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR017096(Kelch-like protein, gigaxonin)|interpro:IPR044072|mint:O95198|rcsb pdb:2XN4|rcsb pdb:4CHB|reactome:R-HSA-8951664|reactome:R-HSA-983168|go:"GO:0042802"(identical protein binding)	refseq:NP_013233.1|sgd:S000004122|dip:DIP-2147N|mint:Q12208|ensemblfungi:YLR132C(gene)|ensemblfungi:YLR132C_mRNA(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0008663"(2',3'-cyclic-nucleotide 2'-phosphodiesterase activity)|go:"GO:0034477"(U6 snRNA 3'-end processing)|go:"GO:1990838"("poly(U)-specific exoribonuclease activity, producing 3' uridine cyclic phosphate ends")|interpro:IPR027521|rcsb pdb:5UQJ	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:tFegR2lJZccRqs4qUjdT3PNjNnk9606	rogid:vJ6GZFlbc3RC9UKZdc4+yyCFQfs559292	intact-crc:F71E0AFD5C9FD199|rigid:ts2j2gMDPH3Sq0bObY1YW9/ucnc	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q12259	uniprotkb:O00505	intact:EBI-30776|uniprotkb:D6VYA8|ensemblfungi:YLR108C	intact:EBI-358297|intact:EBI-28976892|ensembl:ENSP00000261667|uniprotkb:O00191|uniprotkb:O43195|uniprotkb:Q96AA7|uniprotkb:Q5JVM9|intact:EBI-742146|uniprotkb:Q8IYQ9	psi-mi:yl108_yeast(display_long)|uniprotkb:L2913(orf name)|uniprotkb:YLR108C(locus name)	psi-mi:ima4_human(display_long)|uniprotkb:KPNA3(gene name)|psi-mi:KPNA3(display_short)|uniprotkb:QIP2(gene name synonym)|uniprotkb:Karyopherin subunit alpha-3(gene name synonym)|uniprotkb:SRP1-gamma(gene name synonym)|uniprotkb:Importin alpha Q2(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551156|imex:IM-24995-3360	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013209.1|sgd:S000004098|dip:DIP-4075N|ensemblfungi:YLR108C(gene)|ensemblfungi:YLR108C_mRNA(transcript)|go:"GO:0005634"(nucleus)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)	ensembl:ENSG00000102753(gene)|ensembl:ENST00000261667(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0043657"(host cell)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0075732"(viral penetration into host nucleus)|interpro:IPR000225(Armadillo)|refseq:NP_002258.2|ensembl:ENSP00000261667|dip:DIP-27586N|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|mint:O00505|reactome:R-HSA-1169408|reactome:R-HSA-168276	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:CzknxXhhvgMp3J0/oi197EgZ05U559292	rogid:kx/oTYWMYG7dhwJHvr1POLD6FTU9606	intact-crc:C4F13CFDAA21A3A2|rigid:oP3wJrtr1SKXCew1E2EWVOCtGX4	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O43597	uniprotkb:Q12259	intact:EBI-742487|uniprotkb:Q5T6Z7|ensembl:ENSP00000366306|ensembl:ENSP00000366308|uniprotkb:B2R9J9	intact:EBI-30776|uniprotkb:D6VYA8|ensemblfungi:YLR108C	psi-mi:spy2_human(display_long)|uniprotkb:SPRY2(gene name)|psi-mi:SPRY2(display_short)	psi-mi:yl108_yeast(display_long)|uniprotkb:L2913(orf name)|uniprotkb:YLR108C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551152|imex:IM-24995-3359	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005833.1|rcsb pdb:5HL0|reactome:R-HSA-1295596|reactome:R-HSA-182971|rcsb pdb:5HKZ|ensembl:ENST00000377102(transcript)|ensembl:ENST00000377104(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|ensembl:ENSG00000136158(gene)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030291"(protein serine/threonine kinase inhibitor activity)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031345"(negative regulation of cell projection organization)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0032587"(ruffle membrane)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0045165"(cell fate commitment)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048513"(animal organ development)|go:"GO:0051387"(negative regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060437"(lung growth)|go:"GO:0060449"(bud elongation involved in lung branching)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:1900747"(negative regulation of vascular endothelial growth factor signaling pathway)|go:"GO:1902747"(negative regulation of lens fiber cell differentiation)|go:"GO:1990752"(microtubule end)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR007875(Sprouty)|interpro:IPR030780|mint:O43597|rcsb pdb:3BUM|rcsb pdb:3OB1|rcsb pdb:5HKY|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|refseq:NP_001305465.1|refseq:NP_001305466.1|refseq:NP_001305467.1	refseq:NP_013209.1|sgd:S000004098|dip:DIP-4075N|ensemblfungi:YLR108C(gene)|ensemblfungi:YLR108C_mRNA(transcript)|go:"GO:0005634"(nucleus)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:u1omauzisc6MdZlogMotUmtauSI9606	rogid:CzknxXhhvgMp3J0/oi197EgZ05U559292	intact-crc:B6CA51CCF7B0D2CC|rigid:XtjQAWbzgnuhpfG/brce/m9nrpo	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O60684	uniprotkb:Q12259	intact:EBI-359923|uniprotkb:Q5VVU3|uniprotkb:B2RDC7|ensembl:ENSP00000362728|uniprotkb:D3DPP5	intact:EBI-30776|uniprotkb:D6VYA8|ensemblfungi:YLR108C	psi-mi:ima7_human(display_long)|uniprotkb:KPNA6(gene name)|psi-mi:KPNA6(display_short)|uniprotkb:IPOA7(gene name synonym)|uniprotkb:Karyopherin subunit alpha-6(gene name synonym)	psi-mi:yl108_yeast(display_long)|uniprotkb:L2913(orf name)|uniprotkb:YLR108C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551140|imex:IM-24995-3356	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_036448.1|ensembl:ENSG00000025800(gene)|ensembl:ENST00000373625(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0016020"(membrane)|go:"GO:0019079"(viral genome replication)|go:"GO:0030682"(mitigation of host defenses by symbiont)|go:"GO:0043657"(host cell)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060135"(maternal process involved in female pregnancy)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0075506"(entry of viral genome into host nucleus through nuclear pore complex via importin)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:1903902"(positive regulation of viral life cycle)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|mint:O60684|rcsb pdb:4UAD|dip:DIP-27609N	refseq:NP_013209.1|sgd:S000004098|dip:DIP-4075N|ensemblfungi:YLR108C(gene)|ensemblfungi:YLR108C_mRNA(transcript)|go:"GO:0005634"(nucleus)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:3NsSIcE6BHIqYlvfGRolUKD/5uc9606	rogid:CzknxXhhvgMp3J0/oi197EgZ05U559292	intact-crc:1A47F2E5A3D2561F|rigid:j/EP5iQ6fQ+ovJ/LwhRXlkbPquY	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q12259	uniprotkb:O76083-2	intact:EBI-30776|uniprotkb:D6VYA8|ensemblfungi:YLR108C	intact:EBI-11524542|ensembl:ENSP00000335242	psi-mi:yl108_yeast(display_long)|uniprotkb:L2913(orf name)|uniprotkb:YLR108C(locus name)	psi-mi:o76083-2(display_long)|uniprotkb:PDE9A(gene name)|psi-mi:PDE9A(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551144|imex:IM-24995-3357	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013209.1|sgd:S000004098|dip:DIP-4075N|ensemblfungi:YLR108C(gene)|ensemblfungi:YLR108C_mRNA(transcript)|go:"GO:0005634"(nucleus)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)	intact:EBI-742764(isoform-parent)|ensembl:ENSG00000160191(gene)|ensembl:ENST00000335512(transcript)|uniprotkb:O76083-2(isoform-parent)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:CzknxXhhvgMp3J0/oi197EgZ05U559292	rogid:nTzgeYGOwTM/7VJUgxSnlnDiCFo9606	intact-crc:F71A71AC20D5E101|rigid:fim0piZtR6WM9l8dZTek4YNZ1UE	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O00629	uniprotkb:Q12259	intact:EBI-396343|uniprotkb:O00190|intact:EBI-28976443|ensembl:ENSP00000334373|uniprotkb:A8K4S6|uniprotkb:D3DNM2	intact:EBI-30776|uniprotkb:D6VYA8|ensemblfungi:YLR108C	psi-mi:ima3_human(display_long)|uniprotkb:KPNA4(gene name)|psi-mi:KPNA4(display_short)|uniprotkb:QIP1(gene name synonym)|uniprotkb:Karyopherin subunit alpha-4(gene name synonym)|uniprotkb:Importin alpha Q1(gene name synonym)	psi-mi:yl108_yeast(display_long)|uniprotkb:L2913(orf name)|uniprotkb:YLR108C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551148|imex:IM-24995-3358	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002259.1|ensembl:ENSG00000186432(gene)|ensembl:ENST00000334256(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0061608"(nuclear import signal receptor activity)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|mint:O00629|rcsb pdb:4UAE|rcsb pdb:5TBK|rcsb pdb:5XZX|rcsb pdb:6BVV|rcsb pdb:6BVZ|rcsb pdb:6BW9|rcsb pdb:6BWA|rcsb pdb:6BWB|rcsb pdb:6WX8|rcsb pdb:7JJL|reactome:R-HSA-1169408|reactome:R-HSA-168276|ensembl:ENSP00000334373|dip:DIP-32982N	refseq:NP_013209.1|sgd:S000004098|dip:DIP-4075N|ensemblfungi:YLR108C(gene)|ensemblfungi:YLR108C_mRNA(transcript)|go:"GO:0005634"(nucleus)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:/cng/xZ42E2juzHNOpuQTP+amx89606	rogid:CzknxXhhvgMp3J0/oi197EgZ05U559292	intact-crc:6E109A66E7BD9587|rigid:fHEBdR7ZCTLMeY5BYZl1AgEg6R8	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O95751	uniprotkb:Q12318	intact:EBI-740738|ensembl:ENSP00000359557|uniprotkb:Q6IAR6	intact:EBI-37340|uniprotkb:D6VZ12|ensemblfungi:YLR376C	psi-mi:ldoc1_human(display_long)|uniprotkb:Leucine zipper protein down-regulated in cancer cells(gene name synonym)|uniprotkb:LDOC1(gene name)|psi-mi:LDOC1(display_short)|uniprotkb:BCUR1(gene name synonym)	psi-mi:psy3_yeast(display_long)|uniprotkb:PSY3(gene name)|psi-mi:PSY3(display_short)|uniprotkb:L8039.17(orf name)|uniprotkb:YLR376C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551176|imex:IM-24995-3365	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_036449.1|ensembl:ENSG00000182195(gene)|ensembl:ENST00000370526(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071225"(cellular response to muramyl dipeptide)|interpro:IPR032549|interpro:IPR032567	sgd:S000004368|refseq:NP_013480.1|dip:DIP-1903N|ensemblfungi:YLR376C(gene)|ensemblfungi:YLR376C_mRNA(transcript)|go:"GO:0000725"(recombinational repair)|go:"GO:0000730"(DNA recombinase assembly)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0035861"(site of double-strand break)|go:"GO:0070987"(error-free translesion synthesis)|go:"GO:0097196"(Shu complex)|interpro:IPR027417|interpro:IPR031779|rcsb pdb:3VU9|rcsb pdb:4DT1|rcsb pdb:4EQ6|rcsb pdb:5XYN	-	-	crc64:B652FD8113EB4C12	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:Ediu0oNiZ/+YVY8l3fNdgP5A+v09606	rogid:SlNKYcljv2UVV8YxX5/kVQJV/rU559292	intact-crc:B0B5AEDDF08DC2DB|rigid:gF21nbpzGaPczRzexQEg3ER3Bnw	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q08379	uniprotkb:Q12318	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	intact:EBI-37340|uniprotkb:D6VZ12|ensemblfungi:YLR376C	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:psy3_yeast(display_long)|uniprotkb:PSY3(gene name)|psi-mi:PSY3(display_short)|uniprotkb:L8039.17(orf name)|uniprotkb:YLR376C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551172|imex:IM-24995-3364	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N	sgd:S000004368|refseq:NP_013480.1|dip:DIP-1903N|ensemblfungi:YLR376C(gene)|ensemblfungi:YLR376C_mRNA(transcript)|go:"GO:0000725"(recombinational repair)|go:"GO:0000730"(DNA recombinase assembly)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0035861"(site of double-strand break)|go:"GO:0070987"(error-free translesion synthesis)|go:"GO:0097196"(Shu complex)|interpro:IPR027417|interpro:IPR031779|rcsb pdb:3VU9|rcsb pdb:4DT1|rcsb pdb:4EQ6|rcsb pdb:5XYN	-	-	crc64:B652FD8113EB4C12	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2017/05/26	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	rogid:SlNKYcljv2UVV8YxX5/kVQJV/rU559292	intact-crc:274D27FA9D9AD15B|rigid:Lplc7YMVYs7v4PVL6csSKfimvNM	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q12306	uniprotkb:B0QYN7	intact:EBI-17490|uniprotkb:D6VTD1|ensemblfungi:YDR510W	intact:EBI-11525376|ensembl:ENSP00000384361	psi-mi:smt3_yeast(display_long)|uniprotkb:SMT3(gene name)|psi-mi:SMT3(display_short)|uniprotkb:D9719.15(orf name)|uniprotkb:YDR510W(locus name)	psi-mi:b0qyn7_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551160|imex:IM-24995-3361	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010798.1|sgd:S000002918|ensemblfungi:YDR510W(gene)|ensemblfungi:YDR510W_mRNA(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005940"(septin ring)|go:"GO:0016925"(protein sumoylation)|go:"GO:0031386"(protein tag)|go:"GO:0042802"(identical protein binding)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR022617|interpro:IPR029071|rcsb pdb:1EUV|rcsb pdb:1L2N|rcsb pdb:2EKE|rcsb pdb:3PGE|rcsb pdb:3QHT|rcsb pdb:3TIX|rcsb pdb:3UF8|rcsb pdb:3UQA|rcsb pdb:3UQB|rcsb pdb:3V60|rcsb pdb:3V61|rcsb pdb:3V62|rcsb pdb:3VAW|rcsb pdb:4FN2|rcsb pdb:4G50|rcsb pdb:4GGQ|rcsb pdb:4GIV|rcsb pdb:5D6J|rcsb pdb:5JNE|rcsb pdb:5KLX|rcsb pdb:5V8T|rcsb pdb:5YC2|rcsb pdb:5YCA|rcsb pdb:6CFP|rcsb pdb:6P81|rcsb pdb:6Q2S|rcsb pdb:6RPQ|rcsb pdb:6UKM|rcsb pdb:6UKU|rcsb pdb:6UKV|rcsb pdb:6UKW|rcsb pdb:6UKX|rcsb pdb:6UKY|rcsb pdb:6UKZ|rcsb pdb:6UL0|rcsb pdb:6VEL|rcsb pdb:6VW2|rcsb pdb:7LTO|reactome:R-SCE-3065676|reactome:R-SCE-3065678|reactome:R-SCE-3065679|reactome:R-SCE-3108214|reactome:R-SCE-3108232|reactome:R-SCE-3232118|reactome:R-SCE-3899300|reactome:R-SCE-4085377|reactome:R-SCE-4551638|reactome:R-SCE-4570464|reactome:R-SCE-4615885|reactome:R-SCE-9615933|dip:DIP-1364N|mint:Q12306	refseq:XP_005255597.1|refseq:XP_005255598.1|refseq:XP_011520946.1|refseq:XP_011520947.1|ensembl:ENSG00000103275(gene)|ensembl:ENST00000402301(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0016740"(transferase activity)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313	-	crc64:A2790DE7F315E1A7	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:oFdVBxN9WlDXTM7oAnv+1vfcXFQ559292	rogid:zMqQOA+nnCUquTIxAUwemkElTYI9606	intact-crc:C790C58526869E00|rigid:Ep+5f35Rf6pE50RcV2OoAY+y16Q	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P63279	uniprotkb:Q12306	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	intact:EBI-17490|uniprotkb:D6VTD1|ensemblfungi:YDR510W	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:smt3_yeast(display_long)|uniprotkb:SMT3(gene name)|psi-mi:SMT3(display_short)|uniprotkb:D9719.15(orf name)|uniprotkb:YDR510W(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551164|imex:IM-24995-3362	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N	refseq:NP_010798.1|sgd:S000002918|ensemblfungi:YDR510W(gene)|ensemblfungi:YDR510W_mRNA(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005940"(septin ring)|go:"GO:0016925"(protein sumoylation)|go:"GO:0031386"(protein tag)|go:"GO:0042802"(identical protein binding)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR022617|interpro:IPR029071|rcsb pdb:1EUV|rcsb pdb:1L2N|rcsb pdb:2EKE|rcsb pdb:3PGE|rcsb pdb:3QHT|rcsb pdb:3TIX|rcsb pdb:3UF8|rcsb pdb:3UQA|rcsb pdb:3UQB|rcsb pdb:3V60|rcsb pdb:3V61|rcsb pdb:3V62|rcsb pdb:3VAW|rcsb pdb:4FN2|rcsb pdb:4G50|rcsb pdb:4GGQ|rcsb pdb:4GIV|rcsb pdb:5D6J|rcsb pdb:5JNE|rcsb pdb:5KLX|rcsb pdb:5V8T|rcsb pdb:5YC2|rcsb pdb:5YCA|rcsb pdb:6CFP|rcsb pdb:6P81|rcsb pdb:6Q2S|rcsb pdb:6RPQ|rcsb pdb:6UKM|rcsb pdb:6UKU|rcsb pdb:6UKV|rcsb pdb:6UKW|rcsb pdb:6UKX|rcsb pdb:6UKY|rcsb pdb:6UKZ|rcsb pdb:6UL0|rcsb pdb:6VEL|rcsb pdb:6VW2|rcsb pdb:7LTO|reactome:R-SCE-3065676|reactome:R-SCE-3065678|reactome:R-SCE-3065679|reactome:R-SCE-3108214|reactome:R-SCE-3108232|reactome:R-SCE-3232118|reactome:R-SCE-3899300|reactome:R-SCE-4085377|reactome:R-SCE-4551638|reactome:R-SCE-4570464|reactome:R-SCE-4615885|reactome:R-SCE-9615933|dip:DIP-1364N|mint:Q12306	-	-	crc64:A2790DE7F315E1A7	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	rogid:oFdVBxN9WlDXTM7oAnv+1vfcXFQ559292	intact-crc:922321BEB85192E5|rigid:9MPooZox+lbk1ZQnq+lAYhd58B0	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P23497-2	uniprotkb:Q12306	intact:EBI-6589365|ensembl:ENSP00000386404	intact:EBI-17490|uniprotkb:D6VTD1|ensemblfungi:YDR510W	psi-mi:p23497-2(display_long)|uniprotkb:SP100(isoform synonym)|uniprotkb:SP100(gene name)|psi-mi:SP100(display_short)|uniprotkb:Nuclear dot-associated Sp100 protein(gene name synonym)|uniprotkb:Speckled 100 kDa(gene name synonym)|uniprotkb:SP100A(isoform synonym)	psi-mi:smt3_yeast(display_long)|uniprotkb:SMT3(gene name)|psi-mi:SMT3(display_short)|uniprotkb:D9719.15(orf name)|uniprotkb:YDR510W(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551168|imex:IM-24995-3363	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-751145(isoform-parent)|uniprotkb:P23497-2(isoform-parent)|ensembl:ENSG00000067066(gene)|ensembl:ENST00000409341(transcript)	refseq:NP_010798.1|sgd:S000002918|ensemblfungi:YDR510W(gene)|ensemblfungi:YDR510W_mRNA(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005940"(septin ring)|go:"GO:0016925"(protein sumoylation)|go:"GO:0031386"(protein tag)|go:"GO:0042802"(identical protein binding)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR022617|interpro:IPR029071|rcsb pdb:1EUV|rcsb pdb:1L2N|rcsb pdb:2EKE|rcsb pdb:3PGE|rcsb pdb:3QHT|rcsb pdb:3TIX|rcsb pdb:3UF8|rcsb pdb:3UQA|rcsb pdb:3UQB|rcsb pdb:3V60|rcsb pdb:3V61|rcsb pdb:3V62|rcsb pdb:3VAW|rcsb pdb:4FN2|rcsb pdb:4G50|rcsb pdb:4GGQ|rcsb pdb:4GIV|rcsb pdb:5D6J|rcsb pdb:5JNE|rcsb pdb:5KLX|rcsb pdb:5V8T|rcsb pdb:5YC2|rcsb pdb:5YCA|rcsb pdb:6CFP|rcsb pdb:6P81|rcsb pdb:6Q2S|rcsb pdb:6RPQ|rcsb pdb:6UKM|rcsb pdb:6UKU|rcsb pdb:6UKV|rcsb pdb:6UKW|rcsb pdb:6UKX|rcsb pdb:6UKY|rcsb pdb:6UKZ|rcsb pdb:6UL0|rcsb pdb:6VEL|rcsb pdb:6VW2|rcsb pdb:7LTO|reactome:R-SCE-3065676|reactome:R-SCE-3065678|reactome:R-SCE-3065679|reactome:R-SCE-3108214|reactome:R-SCE-3108232|reactome:R-SCE-3232118|reactome:R-SCE-3899300|reactome:R-SCE-4085377|reactome:R-SCE-4551638|reactome:R-SCE-4570464|reactome:R-SCE-4615885|reactome:R-SCE-9615933|dip:DIP-1364N|mint:Q12306	-	isoform-comment:Major isoform.	crc64:A2790DE7F315E1A7	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:HrcogLANB///4vkSYtZ7OtzOb2k9606	rogid:oFdVBxN9WlDXTM7oAnv+1vfcXFQ559292	intact-crc:25055DD512B1D1A6|rigid:HOaD121ckCVmS/vLXZOgjAJqeE8	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O94972	uniprotkb:Q12417	intact:EBI-741602|uniprotkb:Q7Z3E6|uniprotkb:Q8IYF7|uniprotkb:Q8WYF7|intact:EBI-28976055|ensembl:ENSP00000262294|ensembl:ENSP00000376785|uniprotkb:A8K0V9|uniprotkb:A8K8U4|uniprotkb:A8MZ79|uniprotkb:B4DGZ3|uniprotkb:F8WEE6	intact:EBI-710|uniprotkb:D6W3L8|ensemblfungi:YPL151C	psi-mi:tri37_human(display_long)|uniprotkb:Mulibrey nanism protein(gene name synonym)|uniprotkb:TRIM37(gene name)|psi-mi:TRIM37(display_short)|uniprotkb:KIAA0898(gene name synonym)|uniprotkb:MUL(gene name synonym)|uniprotkb:POB1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 37(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM37(gene name synonym)	psi-mi:prp46_yeast(display_long)|uniprotkb:CWC1(gene name synonym)|uniprotkb:PRP nineteen-associated complex protein 50(gene name synonym)|uniprotkb:PRP19-associated complex protein 50(gene name synonym)|uniprotkb:P2594(orf name)|uniprotkb:YPL151C(locus name)|uniprotkb:PRP46(gene name)|psi-mi:PRP46(display_short)|uniprotkb:NTC50(gene name synonym)|uniprotkb:Pre-mRNA-processing protein 46(gene name synonym)|uniprotkb:Complexed with CEF1 protein 1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551200|imex:IM-24995-3371	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001005207.1|refseq:NP_056109.1|refseq:NP_001307916.1|ensembl:ENSP00000262294|ensembl:ENST00000393065|ensembl:ENSP00000376784|ensembl:ENSP00000376785|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046600"(negative regulation of centriole replication)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070842"(aggresome assembly)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002083(MATH)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR008974(TRAF-like)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR037299|rcsb pdb:3LRQ|reactome:R-HSA-983168|ensembl:ENSG00000108395(gene)|ensembl:ENST00000262294(transcript)|ensembl:ENST00000393066(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005777"(peroxisome)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016235"(aggresome)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0035518"(histone H2A monoubiquitination)|refseq:NP_001307919.1|dip:DIP-34437N	refseq:NP_015174.1|sgd:S000006072|ensemblfungi:YPL151C(gene)|ensemblfungi:YPL151C_mRNA(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000974"(Prp19 complex)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|dip:DIP-3994N|mint:Q12417|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q	-	-	crc64:0E888F566A5414BD	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:y2njeO0MUBrKU9MUvkbo1uZmqkE9606	rogid:016ynVER9V3d44NwkqRG7TIvf9w559292	intact-crc:20D766893418DCE3|rigid:KNoTEP3FRmEm2D+VOCvUV7vagdM	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q08379	uniprotkb:Q12417	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	intact:EBI-710|uniprotkb:D6W3L8|ensemblfungi:YPL151C	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:prp46_yeast(display_long)|uniprotkb:CWC1(gene name synonym)|uniprotkb:PRP nineteen-associated complex protein 50(gene name synonym)|uniprotkb:PRP19-associated complex protein 50(gene name synonym)|uniprotkb:P2594(orf name)|uniprotkb:YPL151C(locus name)|uniprotkb:PRP46(gene name)|psi-mi:PRP46(display_short)|uniprotkb:NTC50(gene name synonym)|uniprotkb:Pre-mRNA-processing protein 46(gene name synonym)|uniprotkb:Complexed with CEF1 protein 1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551196|imex:IM-24995-3370	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N	refseq:NP_015174.1|sgd:S000006072|ensemblfungi:YPL151C(gene)|ensemblfungi:YPL151C_mRNA(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000974"(Prp19 complex)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|dip:DIP-3994N|mint:Q12417|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q	-	-	crc64:0E888F566A5414BD	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2017/05/26	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	rogid:016ynVER9V3d44NwkqRG7TIvf9w559292	intact-crc:D7F18452CAA23972|rigid:gKJm6NwORNiNROLKTG4Oi1gRKiY	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O15162	uniprotkb:Q12329	intact:EBI-740019|ensembl:ENSP00000345494|uniprotkb:B2R8H8|uniprotkb:B4DTE8	intact:EBI-8571|uniprotkb:D6VSF3|ensemblfungi:YDR171W	psi-mi:pls1_human(display_long)|uniprotkb:PLSCR1(gene name)|psi-mi:PLSCR1(display_short)|uniprotkb:"Ca(2+)-dependent phospholipid scramblase 1"(gene name synonym)|uniprotkb:Erythrocyte phospholipid scramblase(gene name synonym)|uniprotkb:MmTRA1b(gene name synonym)|uniprotkb:"Mg(2+)-dependent nuclease"(gene name synonym)	psi-mi:hsp42_yeast(display_long)|uniprotkb:HSP42(gene name)|psi-mi:HSP42(display_short)|uniprotkb:YDR171W(locus name)|uniprotkb:YD9395.04(orf name)|uniprotkb:42 kDa heat shock protein(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551180|imex:IM-24995-3366	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000188313(gene)|ensembl:ENST00000342435(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001618"(virus receptor activity)|go:"GO:0003677"(DNA binding)|go:"GO:0004518"(nuclease activity)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006659"(phosphatidylserine biosynthetic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0006953"(acute-phase response)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010288"(response to lead ion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0017121"(plasma membrane phospholipid scrambling)|go:"GO:0017124"(SH3 domain binding)|ensembl:ENSP00000345494|ensembl:ENST00000448787|ensembl:ENSP00000411675|refseq:NP_066928.1|go:"GO:0017128"(phospholipid scramblase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030168"(platelet activation)|go:"GO:0032791"(lead ion binding)|go:"GO:0033003"(regulation of mast cell activation)|go:"GO:0035456"(response to interferon-beta)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0045340"(mercury ion binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0051607"(defense response to virus)|go:"GO:0060368"(regulation of Fc receptor mediated stimulatory signaling pathway)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070782"(phosphatidylserine exposure on apoptotic cell surface)|go:"GO:1905820"(positive regulation of chromosome separation)|go:"GO:2000373"("positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity")|interpro:IPR005552(Scramblase)|mint:O15162|rcsb pdb:1Y2A|refseq:XP_011511209.1|refseq:XP_011511206.1|refseq:XP_005247595.1|refseq:XP_011511208.1|refseq:XP_016862118.1	refseq:NP_010456.1|sgd:S000002578|mint:Q12329|dip:DIP-2515N|ensemblfungi:YDR171W(gene)|ensemblfungi:YDR171W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0009408"(response to heat)|go:"GO:0009651"(response to salt stress)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043621"(protein self-association)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0140311"(protein sequestering activity)|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR031107	-	-	crc64:DF353A76493E3CE6	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:XudfvUkrZbB28t9tpFkokgnDFGc9606	rogid:izvrv04fA3zcBqTeUeHD/erKGf4559292	intact-crc:C299C6D243E5A071|rigid:DQ2v1ZTTgw4SkxNTVvVZCZA3UG0	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q12380	uniprotkb:P49760-3	intact:EBI-2664|uniprotkb:D6W3M0|ensemblfungi:YPL149W	intact:EBI-11535445|ensembl:ENSP00000354856|ensembl:ENSP00000459461	psi-mi:atg5_yeast(display_long)|uniprotkb:ATG5(gene name)|psi-mi:ATG5(display_short)|uniprotkb:APG5(gene name synonym)|uniprotkb:YPL149W(locus name)|uniprotkb:P2601(orf name)	psi-mi:p49760-3(display_long)|uniprotkb:CDC-like kinase 2(gene name synonym)|uniprotkb:CLK2(gene name)|psi-mi:CLK2(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551188|imex:IM-24995-3368	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015176.1|sgd:S000006070|reactome:R-SCE-1632852|dip:DIP-1195N|reactome:R-SCE-8934903|ensemblfungi:YPL149W(gene)|ensemblfungi:YPL149W_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005634"(nucleus)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0006501"(C-terminal protein lipidation)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016020"(membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0016787"(hydrolase activity)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034274"(Atg12-Atg5-Atg16 complex)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044804"(autophagy of nucleus)|go:"GO:0044805"(late nucleophagy)|go:"GO:0061908"(phagophore)|go:"GO:0061912"(selective autophagy)|go:"GO:0120095"(vacuole-isolation membrane contact site)|go:"GO:0140355"(cargo receptor ligand activity)|interpro:IPR007239(Autophagy protein 5)|interpro:IPR042526|interpro:IPR042527|rcsb pdb:2DYM|rcsb pdb:2DYO|rcsb pdb:3W1S	intact:EBI-750020(isoform-parent)|ensembl:ENSG00000176444(gene)|ensembl:ENSG00000261893(gene)|ensembl:ENST00000361168(transcript)|ensembl:ENST00000572269(transcript)|uniprotkb:P49760-3(isoform-parent)	-	crc64:BE513A631DEAA0A1	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:PMSbzCApcY0S518yzmdDm3bPY74559292	rogid:wFw4PjPFbFOw5k9Fqay3nAen8ZI9606	intact-crc:C6334F9015E52630|rigid:5tumTh+hsOZZ9hC+VgM3hQfs+Qg	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q12329	uniprotkb:A0A024R0Y4	intact:EBI-8571|uniprotkb:D6VSF3|ensemblfungi:YDR171W	intact:EBI-11523730|ensembl:ENSP00000477709|ensembl:ENSP00000478363|ensembl:ENSP00000481091	psi-mi:hsp42_yeast(display_long)|uniprotkb:HSP42(gene name)|psi-mi:HSP42(display_short)|uniprotkb:YDR171W(locus name)|uniprotkb:YD9395.04(orf name)|uniprotkb:42 kDa heat shock protein(gene name synonym)	psi-mi:a0a024r0y4_human(display_long)|uniprotkb:TADA2A(gene name)|psi-mi:TADA2A(display_short)|uniprotkb:TADA2L(gene name synonym)|uniprotkb:hCG_28187(orf name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551184|imex:IM-24995-3367	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010456.1|sgd:S000002578|mint:Q12329|dip:DIP-2515N|ensemblfungi:YDR171W(gene)|ensemblfungi:YDR171W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0009408"(response to heat)|go:"GO:0009651"(response to salt stress)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043621"(protein self-association)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0140311"(protein sequestering activity)|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR031107	refseq:NP_001159577.2|refseq:NP_001479.4|ensembl:ENSG00000276234(gene)|ensembl:ENST00000612272(transcript)|ensembl:ENST00000615182(transcript)|ensembl:ENST00000620628(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031063"(regulation of histone deacetylation)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0035065"(regulation of histone acetylation)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090043"(regulation of tubulin deacetylation)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016827(Transcriptional adaptor 2)|interpro:IPR017884|interpro:IPR017930|interpro:IPR036388|interpro:IPR041983|interpro:IPR043145	-	crc64:DF353A76493E3CE6	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:izvrv04fA3zcBqTeUeHD/erKGf4559292	rogid:IGh7vC68gMLe+tAVGM4gc0rzc6Y9606	intact-crc:56833088178CABD4|rigid:AhFQF+UySGeUroxxo6tJBS1uzRk	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O14641	uniprotkb:Q12389	intact:EBI-740850|ensembl:ENSP00000005340|uniprotkb:Q53XM0|uniprotkb:D3DTN3	intact:EBI-5644|uniprotkb:D6VRW1|ensemblfungi:YDL031W	psi-mi:dvl2_human(display_long)|uniprotkb:DSH homolog 2(gene name synonym)|uniprotkb:DVL2(gene name)|psi-mi:DVL2(display_short)	psi-mi:dbp10_yeast(display_long)|uniprotkb:DBP10(gene name)|psi-mi:DBP10(display_short)|uniprotkb:YDL031W(locus name)|uniprotkb:D2770(orf name)|uniprotkb:DEAD box protein 10(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551192|imex:IM-24995-3369	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004413.1|ensembl:ENSG00000004975(gene)|ensembl:ENST00000005340(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005109"(frizzled binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0007507"(heart development)|go:"GO:0016235"(aggresome)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044340"(canonical Wnt signaling pathway involved in regulation of cell proliferation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0150012"(positive regulation of neuron projection arborization)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008341(Dishevelled-2 region)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:O14641|rcsb pdb:2REY|rcsb pdb:3CBX|rcsb pdb:3CBY|rcsb pdb:3CBZ|rcsb pdb:3CC0|rcsb pdb:4WIP|rcsb pdb:5LNP|rcsb pdb:5SUY|rcsb pdb:5SUZ|rcsb pdb:6IW3|rcsb pdb:6JCK|reactome:R-HSA-201681|reactome:R-HSA-201688|reactome:R-HSA-2028269|reactome:R-HSA-4086400|reactome:R-HSA-4608870|reactome:R-HSA-4641258|reactome:R-HSA-4641262|reactome:R-HSA-5099900|reactome:R-HSA-5368598|reactome:R-HSA-5663220|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9673324|ensembl:ENSP00000005340|dip:DIP-34433N	refseq:NP_010253.2|sgd:S000002189|dip:DIP-6387N|mint:Q12389|ensemblfungi:YDL031W(gene)|ensemblfungi:YDL031W_mRNA(transcript)|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000466"("maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0042802"(identical protein binding)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902626"(assembly of large subunit precursor of preribosome)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR012541(DBP10CT)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|interpro:IPR033517	-	-	crc64:0533013C276095DF	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:2Vdc8oRnT4Mz/j+EXQXrL3AszOc9606	rogid:PHnLvx2Kk2uAkF21YkvqyoJqTWg559292	intact-crc:CBF1E0D85137768C|rigid:hCU0PErWfmZc22HNiL+Lm8Gk1Zk	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O43639	uniprotkb:Q12446	intact:EBI-713635|uniprotkb:Q9BWN9|uniprotkb:Q9UIC3|ensembl:ENSP00000233154|ensembl:ENSP00000377018|uniprotkb:D3DVK1	intact:EBI-10022|uniprotkb:D6W2N7|ensemblfungi:YOR181W	psi-mi:nck2_human(display_long)|uniprotkb:NCK adaptor protein 2(gene name synonym)|uniprotkb:SH2/SH3 adaptor protein NCK-beta(gene name synonym)|uniprotkb:NCK2(gene name)|psi-mi:NCK2(display_short)|uniprotkb:GRB4(gene name synonym)|uniprotkb:Growth factor receptor-bound protein 4(gene name synonym)	psi-mi:las17_yeast(display_long)|uniprotkb:LAS17(gene name)|psi-mi:LAS17(display_short)|uniprotkb:YOR181W(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551220|imex:IM-24995-3376	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006712860.1|refseq:NP_001004720.1|refseq:NP_003572.2|ensembl:ENSG00000071051(gene)|ensembl:ENST00000233154(transcript)|ensembl:ENST00000393349(transcript)|go:"GO:0001771"(immunological synapse formation)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0007015"(actin filament organization)|go:"GO:0007165"(signal transduction)|go:"GO:0007172"(signal complex assembly)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007176"(regulation of epidermal growth factor-activated receptor activity)|go:"GO:0008093"(cytoskeletal anchor activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0012506"(vesicle membrane)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016477"(cell migration)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0036493"(positive regulation of translation in response to endoplasmic reticulum stress)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042110"(T cell activation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0060996"(dendritic spine development)|go:"GO:0097110"(scaffold protein binding)|go:"GO:1902237"(positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903898"(negative regulation of PERK-mediated unfolded protein response)|go:"GO:1903912"(negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation)|go:"GO:1990441"(negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR017304(Cytoplasmic, NCK)|interpro:IPR028524|interpro:IPR035559|interpro:IPR035560|interpro:IPR035561|interpro:IPR035883|interpro:IPR036028|interpro:IPR036860|mint:O43639|rcsb pdb:1U5S|rcsb pdb:1WX6|rcsb pdb:1Z3K|rcsb pdb:2B86|rcsb pdb:2CIA|rcsb pdb:2FRW|rcsb pdb:2FRY|rcsb pdb:2JXB|rcsb pdb:4E6R|reactome:R-HSA-186763|reactome:R-HSA-373753|reactome:R-HSA-3928664|reactome:R-HSA-428540|reactome:R-HSA-4420097|reactome:R-HSA-8985801|reactome:R-HSA-9013420|reactome:R-HSA-9013424|refseq:XP_016860592.1|refseq:XP_016860593.1|refseq:XP_016860594.1|refseq:XP_011510293.1	refseq:NP_014824.1|sgd:S000005707|ensemblfungi:YOR181W(gene)|ensemblfungi:YOR181W_mRNA(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007015"(actin filament organization)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030479"(actin cortical patch)|go:"GO:0032233"(positive regulation of actin filament bundle assembly)|go:"GO:0043332"(mating projection tip)|go:"GO:0045010"(actin nucleation)|go:"GO:0051666"(actin cortical patch localization)|go:"GO:0071933"(Arp2/3 complex binding)|go:"GO:0140224"(SLAC complex)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR000697(EVH1)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR027641|interpro:IPR033927|rcsb pdb:1ZUK|dip:DIP-963N|mint:Q12446	-	-	crc64:4488355563AA2645	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:WV9nJ78Im/ga5KQlRuSN2ODzWpQ9606	rogid:TfQ256gBQPp1T8Ntu2AvktFnypA559292	intact-crc:E5EF3DE47A2EA4BD|rigid:RsfL2QngUqX+Q1QuSE7cTsedaZ8	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O43586	uniprotkb:Q12446	intact:EBI-1050964|uniprotkb:O43585|uniprotkb:O95657|uniprotkb:B5BUK4|uniprotkb:B5BU74|ensembl:ENSP00000452746	intact:EBI-10022|uniprotkb:D6W2N7|ensemblfungi:YOR181W	psi-mi:ppip1_human(display_long)|uniprotkb:CD2-binding protein 1(gene name synonym)|uniprotkb:H-PIP(gene name synonym)|uniprotkb:PSTPIP1(gene name)|psi-mi:PSTPIP1(display_short)|uniprotkb:CD2BP1(gene name synonym)	psi-mi:las17_yeast(display_long)|uniprotkb:LAS17(gene name)|psi-mi:LAS17(display_short)|uniprotkb:YOR181W(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551216|imex:IM-24995-3375	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003969.2|refseq:NP_001308064.1|refseq:NP_001308066.1|ensembl:ENSG00000140368(gene)|ensembl:ENST00000558012(transcript)|go:"GO:0001931"(uropod)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0006954"(inflammatory response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0032154"(cleavage furrow)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051015"(actin filament binding)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR027267|interpro:IPR030777|interpro:IPR031160|interpro:IPR036028|mint:O43586|rcsb pdb:2DIL|reactome:R-HSA-844456|reactome:R-HSA-9660826	refseq:NP_014824.1|sgd:S000005707|ensemblfungi:YOR181W(gene)|ensemblfungi:YOR181W_mRNA(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007015"(actin filament organization)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030479"(actin cortical patch)|go:"GO:0032233"(positive regulation of actin filament bundle assembly)|go:"GO:0043332"(mating projection tip)|go:"GO:0045010"(actin nucleation)|go:"GO:0051666"(actin cortical patch localization)|go:"GO:0071933"(Arp2/3 complex binding)|go:"GO:0140224"(SLAC complex)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR000697(EVH1)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR027641|interpro:IPR033927|rcsb pdb:1ZUK|dip:DIP-963N|mint:Q12446	-	-	crc64:4488355563AA2645	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:JWK4dCYdcVF6mKwe+hoOri1wwps9606	rogid:TfQ256gBQPp1T8Ntu2AvktFnypA559292	intact-crc:323195E8F821F11C|rigid:xMK64f8TXbrA2jdbHT/A3Faf260	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q12439	uniprotkb:O75928-2	intact:EBI-2342872|uniprotkb:D6W2Q1	intact:EBI-348567|ensembl:ENSP00000317163|intact:EBI-7259183|intact:MINT-1455402	psi-mi:yo21a_yeast(display_long)|uniprotkb:TY2A-OR1(gene name)|psi-mi:TY2A-OR1(display_short)|uniprotkb:YORCTy2-1 GAG(gene name synonym)|uniprotkb:O4787(orf name)|uniprotkb:YOR192C-A(locus name)	psi-mi:o75928-2(display_long)|uniprotkb:Msx-interacting zinc finger protein(gene name synonym)|uniprotkb:PIAS-NY protein(gene name synonym)|uniprotkb:Protein inhibitor of activated STAT x(gene name synonym)|uniprotkb:Protein inhibitor of activated STAT2(gene name synonym)|uniprotkb:PIAS2(gene name)|psi-mi:PIAS2(display_short)|uniprotkb:PIASX(gene name synonym)|uniprotkb:Androgen receptor-interacting protein 3(gene name synonym)|uniprotkb:DAB2-interacting protein(gene name synonym)|uniprotkb:PIASx-alpha(isoform synonym)|uniprotkb:ARIP3(isoform synonym)|uniprotkb:E3 SUMO-protein transferase PIAS2(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551204|imex:IM-24995-3372	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000007353|interpro:IPR015820(Retrotransposon Ty1 A, N-terminal)|refseq:NP_058186.1|go:"GO:0000943"(retrotransposon nucleocapsid)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0032197"(transposition, RNA-mediated)	intact:EBI-348555(pias2_human)|ensembl:ENSG00000078043(gene)|ensembl:ENST00000324794(transcript)|uniprotkb:O75928-2(isoform-parent)	-	-	isoform-comment:"Contains a glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) at position 562."	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:IbfwV+zl9+6yPnQgzLPL0tLgx5s559292	rogid:JNC3UGf8YuVcrXbFnO27d4orf4I9606	intact-crc:F7B6743569683262|rigid:7gCJHwxB2mFvsGjlOGmatiloMro	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O14641	uniprotkb:Q12439	intact:EBI-740850|ensembl:ENSP00000005340|uniprotkb:Q53XM0|uniprotkb:D3DTN3	intact:EBI-2342872|uniprotkb:D6W2Q1	psi-mi:dvl2_human(display_long)|uniprotkb:DSH homolog 2(gene name synonym)|uniprotkb:DVL2(gene name)|psi-mi:DVL2(display_short)	psi-mi:yo21a_yeast(display_long)|uniprotkb:TY2A-OR1(gene name)|psi-mi:TY2A-OR1(display_short)|uniprotkb:YORCTy2-1 GAG(gene name synonym)|uniprotkb:O4787(orf name)|uniprotkb:YOR192C-A(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551208|imex:IM-24995-3373	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004413.1|ensembl:ENSG00000004975(gene)|ensembl:ENST00000005340(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005109"(frizzled binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0007507"(heart development)|go:"GO:0016235"(aggresome)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044340"(canonical Wnt signaling pathway involved in regulation of cell proliferation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0150012"(positive regulation of neuron projection arborization)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008341(Dishevelled-2 region)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:O14641|rcsb pdb:2REY|rcsb pdb:3CBX|rcsb pdb:3CBY|rcsb pdb:3CBZ|rcsb pdb:3CC0|rcsb pdb:4WIP|rcsb pdb:5LNP|rcsb pdb:5SUY|rcsb pdb:5SUZ|rcsb pdb:6IW3|rcsb pdb:6JCK|reactome:R-HSA-201681|reactome:R-HSA-201688|reactome:R-HSA-2028269|reactome:R-HSA-4086400|reactome:R-HSA-4608870|reactome:R-HSA-4641258|reactome:R-HSA-4641262|reactome:R-HSA-5099900|reactome:R-HSA-5368598|reactome:R-HSA-5663220|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9673324|ensembl:ENSP00000005340|dip:DIP-34433N	sgd:S000007353|interpro:IPR015820(Retrotransposon Ty1 A, N-terminal)|refseq:NP_058186.1|go:"GO:0000943"(retrotransposon nucleocapsid)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0032197"(transposition, RNA-mediated)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:2Vdc8oRnT4Mz/j+EXQXrL3AszOc9606	rogid:IbfwV+zl9+6yPnQgzLPL0tLgx5s559292	intact-crc:91E13789BCA6B82F|rigid:yfRPz+N95NdSBBchwTwQi26ibj4	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q12439	uniprotkb:P63279	intact:EBI-2342872|uniprotkb:D6W2Q1	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	psi-mi:yo21a_yeast(display_long)|uniprotkb:TY2A-OR1(gene name)|psi-mi:TY2A-OR1(display_short)|uniprotkb:YORCTy2-1 GAG(gene name synonym)|uniprotkb:O4787(orf name)|uniprotkb:YOR192C-A(locus name)	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551212|imex:IM-24995-3374	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000007353|interpro:IPR015820(Retrotransposon Ty1 A, N-terminal)|refseq:NP_058186.1|go:"GO:0000943"(retrotransposon nucleocapsid)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0032197"(transposition, RNA-mediated)	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:IbfwV+zl9+6yPnQgzLPL0tLgx5s559292	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	intact-crc:DC62F6F404F52F69|rigid:mwSLHioTwi1SSdJjPRevAC+8v9o	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q12476	uniprotkb:O14641	intact:EBI-31475|uniprotkb:D6VRH7|ensemblfungi:YDL175C	intact:EBI-740850|ensembl:ENSP00000005340|uniprotkb:Q53XM0|uniprotkb:D3DTN3	psi-mi:air2_yeast(display_long)|uniprotkb:Arginine methyltransferase-interacting RING finger protein 2(gene name synonym)|uniprotkb:AIR2(gene name)|psi-mi:AIR2(display_short)|uniprotkb:YDL175C(locus name)	psi-mi:dvl2_human(display_long)|uniprotkb:DSH homolog 2(gene name synonym)|uniprotkb:DVL2(gene name)|psi-mi:DVL2(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551224|imex:IM-24995-3377	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010106.1|sgd:S000002334|dip:DIP-2543N|mint:Q12476|ensemblfungi:YDL175C(gene)|ensemblfungi:YDL175C_mRNA(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0006400"(tRNA modification)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031499"(TRAMP complex)|go:"GO:0043629"(ncRNA polyadenylation)|go:"GO:0071031"(nuclear mRNA surveillance of mRNA 3'-end processing)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071036"(nuclear polyadenylation-dependent snoRNA catabolic process)|go:"GO:0071037"(nuclear polyadenylation-dependent snRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071039"(nuclear polyadenylation-dependent CUT catabolic process)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR016713("Poly(A) polymerase complex, Air1/2")|interpro:IPR036875|rcsb pdb:2LLI|rcsb pdb:3NYB|rcsb pdb:4U4C	refseq:NP_004413.1|ensembl:ENSG00000004975(gene)|ensembl:ENST00000005340(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005109"(frizzled binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0007507"(heart development)|go:"GO:0016235"(aggresome)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044340"(canonical Wnt signaling pathway involved in regulation of cell proliferation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0150012"(positive regulation of neuron projection arborization)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008341(Dishevelled-2 region)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:O14641|rcsb pdb:2REY|rcsb pdb:3CBX|rcsb pdb:3CBY|rcsb pdb:3CBZ|rcsb pdb:3CC0|rcsb pdb:4WIP|rcsb pdb:5LNP|rcsb pdb:5SUY|rcsb pdb:5SUZ|rcsb pdb:6IW3|rcsb pdb:6JCK|reactome:R-HSA-201681|reactome:R-HSA-201688|reactome:R-HSA-2028269|reactome:R-HSA-4086400|reactome:R-HSA-4608870|reactome:R-HSA-4641258|reactome:R-HSA-4641262|reactome:R-HSA-5099900|reactome:R-HSA-5368598|reactome:R-HSA-5663220|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9673324|ensembl:ENSP00000005340|dip:DIP-34433N	-	crc64:5915C97FA39D6AFC	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:bgMS2UPxQlkuE3+ip5+hgnIdNrE559292	rogid:2Vdc8oRnT4Mz/j+EXQXrL3AszOc9606	intact-crc:30A043B83F4F10FE|rigid:+Y9vAv49+0LSxYqVFXNA/5VMQgU	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P41902	uniprotkb:Q12800	intact:EBI-5162|uniprotkb:D6W296	intact:EBI-717422|uniprotkb:Q12801|uniprotkb:Q9UD77|uniprotkb:A8K5E9|uniprotkb:Q9UD75|ensembl:ENSP00000257915	psi-mi:crs5_yeast(display_long)|uniprotkb:CRS5(gene name)|psi-mi:CRS5(display_short)|uniprotkb:O2675(orf name)|uniprotkb:YOR031W(locus name)	psi-mi:tfcp2_human(display_long)|uniprotkb:Transcription factor LSF(gene name synonym)|uniprotkb:SAA3 enhancer factor(gene name synonym)|uniprotkb:TFCP2(gene name)|psi-mi:TFCP2(display_short)|uniprotkb:LSF(gene name synonym)|uniprotkb:SEF(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551244|imex:IM-24995-3382	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005557|dip:DIP-5511N|go:"GO:0005507"(copper ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0010038"(response to metal ion)|interpro:IPR035715	refseq:NP_001166923.1|refseq:NP_001166924.1|refseq:NP_005644.2|ensembl:ENSG00000135457(gene)|ensembl:ENST00000257915(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR007604(CP2 transcription factor)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR037599|interpro:IPR041418|mint:Q12800	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:j4oJEwGSOVJeLFRydjF0k9ASq14559292	rogid:M7mQ08NDYxuawmUEKRgjSdIr+Og9606	intact-crc:9E2473A52DE794C7|rigid:Ptae9zJfdvTrIUq6XDJvdTnn7GM	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q12481	uniprotkb:O14641	intact:EBI-31770|uniprotkb:D6W2Y5|ensemblfungi:YOR287C	intact:EBI-740850|ensembl:ENSP00000005340|uniprotkb:Q53XM0|uniprotkb:D3DTN3	psi-mi:rrp36_yeast(display_long)|uniprotkb:RRP36(gene name)|psi-mi:RRP36(display_short)|uniprotkb:Ribosomal RNA-processing protein 36(gene name synonym)|uniprotkb:YOR287C(locus name)	psi-mi:dvl2_human(display_long)|uniprotkb:DSH homolog 2(gene name synonym)|uniprotkb:DVL2(gene name)|psi-mi:DVL2(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551228|imex:IM-24995-3378	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014930.1|sgd:S000005813|interpro:IPR009292(Protein of unknown function DUF947)|mint:Q12481|ensemblfungi:YOR287C(gene)|ensemblfungi:YOR287C_mRNA(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000469"(cleavage involved in rRNA processing)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0030686"(90S preribosome)|go:"GO:0042274"(ribosomal small subunit biogenesis)|reactome:R-SCE-6791226	refseq:NP_004413.1|ensembl:ENSG00000004975(gene)|ensembl:ENST00000005340(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005109"(frizzled binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0007507"(heart development)|go:"GO:0016235"(aggresome)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044340"(canonical Wnt signaling pathway involved in regulation of cell proliferation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0150012"(positive regulation of neuron projection arborization)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008341(Dishevelled-2 region)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:O14641|rcsb pdb:2REY|rcsb pdb:3CBX|rcsb pdb:3CBY|rcsb pdb:3CBZ|rcsb pdb:3CC0|rcsb pdb:4WIP|rcsb pdb:5LNP|rcsb pdb:5SUY|rcsb pdb:5SUZ|rcsb pdb:6IW3|rcsb pdb:6JCK|reactome:R-HSA-201681|reactome:R-HSA-201688|reactome:R-HSA-2028269|reactome:R-HSA-4086400|reactome:R-HSA-4608870|reactome:R-HSA-4641258|reactome:R-HSA-4641262|reactome:R-HSA-5099900|reactome:R-HSA-5368598|reactome:R-HSA-5663220|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9673324|ensembl:ENSP00000005340|dip:DIP-34433N	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:q1HXpxSZvQpnhGzVXmnBNEfWTzI559292	rogid:2Vdc8oRnT4Mz/j+EXQXrL3AszOc9606	intact-crc:BF3C8B235B909D20|rigid:urwWPQOYg+0Za6KFpv7PEA0rWqo	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P25372	uniprotkb:Q12800	intact:EBI-19616|uniprotkb:D6VR84|ensemblfungi:YCR083W	intact:EBI-717422|uniprotkb:Q12801|uniprotkb:Q9UD77|uniprotkb:A8K5E9|uniprotkb:Q9UD75|ensembl:ENSP00000257915	psi-mi:trx3_yeast(display_long)|uniprotkb:TRX3(gene name)|psi-mi:TRX3(display_short)|uniprotkb:YCR83W(orf name)|uniprotkb:YCR083W(locus name)	psi-mi:tfcp2_human(display_long)|uniprotkb:Transcription factor LSF(gene name synonym)|uniprotkb:SAA3 enhancer factor(gene name synonym)|uniprotkb:TFCP2(gene name)|psi-mi:TFCP2(display_short)|uniprotkb:LSF(gene name synonym)|uniprotkb:SEF(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551236|imex:IM-24995-3380	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR036249|refseq:NP_010006.1|sgd:S000000679|interpro:IPR017937|interpro:IPR013766(Thioredoxin domain)|rcsb pdb:2OE0|rcsb pdb:2OE1|rcsb pdb:2OE3|ensemblfungi:YCR083W(gene)|ensemblfungi:YCR083W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0015036"(disulfide oxidoreductase activity)|go:"GO:0034599"(cellular response to oxidative stress)|rcsb pdb:5YKW	refseq:NP_001166923.1|refseq:NP_001166924.1|refseq:NP_005644.2|ensembl:ENSG00000135457(gene)|ensembl:ENST00000257915(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR007604(CP2 transcription factor)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR037599|interpro:IPR041418|mint:Q12800	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:g0xjGf9GvJRl8iv2qoT5tOs7jXI559292	rogid:M7mQ08NDYxuawmUEKRgjSdIr+Og9606	intact-crc:42B10BEB4AC5794E|rigid:32XPbIfd3r2o9unzkwhEZF9w+Kk	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q12527	uniprotkb:O43597	intact:EBI-31977|uniprotkb:D6W457|ensemblfungi:YPR049C	intact:EBI-742487|uniprotkb:Q5T6Z7|ensembl:ENSP00000366306|ensembl:ENSP00000366308|uniprotkb:B2R9J9	psi-mi:atg11_yeast(display_long)|uniprotkb:Cytoplasm to vacuole targeting protein 9(gene name synonym)|uniprotkb:ATG11(gene name)|psi-mi:ATG11(display_short)|uniprotkb:CVT9(gene name synonym)|uniprotkb:YPR049C(locus name)|uniprotkb:YP9499.07c(orf name)	psi-mi:spy2_human(display_long)|uniprotkb:SPRY2(gene name)|psi-mi:SPRY2(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551232|imex:IM-24995-3379	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015374.1|sgd:S000006253|dip:DIP-1492N|mint:Q12527|ensemblfungi:YPR049C(gene)|ensemblfungi:YPR049C_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000149"(SNARE binding)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0006914"(autophagy)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0034629"|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061709"(reticulophagy)|go:"GO:0140255"(regulation of cellular response to phosphate starvation)|go:"GO:1990316"(Atg1/ULK1 kinase complex)|go:"GO:2000786"(positive regulation of autophagosome assembly)|interpro:IPR019460|interpro:IPR040040|rcsb pdb:6VZF|reactome:R-SCE-1632852	refseq:NP_005833.1|rcsb pdb:5HL0|reactome:R-HSA-1295596|reactome:R-HSA-182971|rcsb pdb:5HKZ|ensembl:ENST00000377102(transcript)|ensembl:ENST00000377104(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|ensembl:ENSG00000136158(gene)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030291"(protein serine/threonine kinase inhibitor activity)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031345"(negative regulation of cell projection organization)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0032587"(ruffle membrane)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0045165"(cell fate commitment)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048513"(animal organ development)|go:"GO:0051387"(negative regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060437"(lung growth)|go:"GO:0060449"(bud elongation involved in lung branching)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:1900747"(negative regulation of vascular endothelial growth factor signaling pathway)|go:"GO:1902747"(negative regulation of lens fiber cell differentiation)|go:"GO:1990752"(microtubule end)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR007875(Sprouty)|interpro:IPR030780|mint:O43597|rcsb pdb:3BUM|rcsb pdb:3OB1|rcsb pdb:5HKY|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|refseq:NP_001305465.1|refseq:NP_001305466.1|refseq:NP_001305467.1	-	crc64:A904B92E9AE79449	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:26PElwvrl3YKwoQU7YdkmR0ln3o559292	rogid:u1omauzisc6MdZlogMotUmtauSI9606	intact-crc:390182D2C01D9BDB|rigid:a/f0lR/A9heQ5jUrRycNpH6q0PA	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q12800	uniprotkb:P38340	intact:EBI-717422|uniprotkb:Q12801|uniprotkb:Q9UD77|uniprotkb:A8K5E9|uniprotkb:Q9UD75|ensembl:ENSP00000257915	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:tfcp2_human(display_long)|uniprotkb:Transcription factor LSF(gene name synonym)|uniprotkb:SAA3 enhancer factor(gene name synonym)|uniprotkb:TFCP2(gene name)|psi-mi:TFCP2(display_short)|uniprotkb:LSF(gene name synonym)|uniprotkb:SEF(gene name synonym)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551240|imex:IM-24995-3381	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001166923.1|refseq:NP_001166924.1|refseq:NP_005644.2|ensembl:ENSG00000135457(gene)|ensembl:ENST00000257915(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR007604(CP2 transcription factor)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR037599|interpro:IPR041418|mint:Q12800	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F	-	-	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:M7mQ08NDYxuawmUEKRgjSdIr+Og9606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:C2664BDAC7EB48E7|rigid:yH67WZVVVPUmvnYbu6oMf54oRps	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q12846	uniprotkb:Q08144	intact:EBI-744942|uniprotkb:Q15525|ensembl:ENSP00000317714|uniprotkb:Q6FHE8|uniprotkb:A8MXY0	intact:EBI-19302|uniprotkb:D6W248|uniprotkb:E9P933|ensemblfungi:YOL018C	psi-mi:stx4_human(display_long)|uniprotkb:Renal carcinoma antigen NY-REN-31(gene name synonym)|uniprotkb:STX4(gene name)|psi-mi:STX4(display_short)|uniprotkb:STX4A(gene name synonym)	psi-mi:tlg2_yeast(display_long)|uniprotkb:YOL018C(locus name)|uniprotkb:TLG2(gene name)|psi-mi:TLG2(display_short)|uniprotkb:Syntaxin TLG2(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551268|imex:IM-24995-3388	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000103496(gene)|refseq:NP_004595.2|ensembl:ENST00000313843(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0000322"(storage vacuole)|go:"GO:0002639"(positive regulation of immunoglobulin production)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005768"(endosome)|go:"GO:0005773"(vacuole)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006887"(exocytosis)|go:"GO:0006906"(vesicle fusion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016230"(sphingomyelin phosphodiesterase activator activity)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0032589"(neuron projection membrane)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035493"(SNARE complex assembly)|go:"GO:0035749"(myelin sheath adaxonal region)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0036477"(somatodendritic compartment)|go:"GO:0042581"(specific granule)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043197"(dendritic spine)|go:"GO:0043219"(lateral loop)|go:"GO:0043311"(positive regulation of eosinophil degranulation)|go:"GO:0045202"(synapse)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0048278"(vesicle docking)|go:"GO:0048284"(organelle fusion)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048787"(presynaptic active zone membrane)|go:"GO:0050921"(positive regulation of chemotaxis)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1902041"(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1903575"(cornified envelope assembly)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|reactome:R-HSA-114516|reactome:R-HSA-1236974|reactome:R-HSA-1445148|reactome:R-HSA-199992|reactome:R-HSA-449836|interpro:IPR006011(Syntaxin, N-terminal)|refseq:NP_001259025.1	refseq:NP_014624.1|sgd:S000005378|ensemblfungi:YOL018C(gene)|ensemblfungi:YOL018C_mRNA(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006673"(inositol phosphoceramide metabolic process)|go:"GO:0006675"(mannosyl-inositol phosphorylceramide metabolic process)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0031303"(integral component of endosome membrane)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0032527"(protein exit from endoplasmic reticulum)|go:"GO:0048278"(vesicle docking)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|interpro:IPR028673|reactome:R-SCE-6811440|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0006897"(endocytosis)|go:"GO:0006906"(vesicle fusion)|go:"GO:0009306"(protein secretion)|dip:DIP-4244N|mint:Q08144	-	-	crc64:CEBD6FE11278B1F0	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:NvOLGIGe/XO2aDPSpdPzrtKniZY9606	rogid:M7Ezt/D1lvPf/T8TrjQwtKNhFhw559292	intact-crc:75361DC33CF7D54D|rigid:Z47hgCTIBXp+/pzO7xUoEJ74PoY	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P25385	uniprotkb:Q12846	intact:EBI-3735|uniprotkb:D6VY78|ensemblfungi:YLR078C	intact:EBI-744942|uniprotkb:Q15525|ensembl:ENSP00000317714|uniprotkb:Q6FHE8|uniprotkb:A8MXY0	psi-mi:bos1_yeast(display_long)|uniprotkb:BOS1(gene name)|psi-mi:BOS1(display_short)|uniprotkb:YLR078C(locus name)|uniprotkb:L9449.9(orf name)|uniprotkb:Bet one suppressor 1(gene name synonym)	psi-mi:stx4_human(display_long)|uniprotkb:Renal carcinoma antigen NY-REN-31(gene name synonym)|uniprotkb:STX4(gene name)|psi-mi:STX4(display_short)|uniprotkb:STX4A(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551264|imex:IM-24995-3387	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013179.1|sgd:S000004068|reactome:R-SCE-204005|reactome:R-SCE-5694530|reactome:R-SCE-6807878|dip:DIP-2020N|ensemblfungi:YLR078C(gene)|ensemblfungi:YLR078C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0006906"(vesicle fusion)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0031902"(late endosome membrane)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0048280"(vesicle fusion with Golgi apparatus)|interpro:IPR027027	ensembl:ENSG00000103496(gene)|refseq:NP_004595.2|ensembl:ENST00000313843(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0000322"(storage vacuole)|go:"GO:0002639"(positive regulation of immunoglobulin production)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005768"(endosome)|go:"GO:0005773"(vacuole)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006887"(exocytosis)|go:"GO:0006906"(vesicle fusion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016230"(sphingomyelin phosphodiesterase activator activity)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0032589"(neuron projection membrane)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035493"(SNARE complex assembly)|go:"GO:0035749"(myelin sheath adaxonal region)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0036477"(somatodendritic compartment)|go:"GO:0042581"(specific granule)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043197"(dendritic spine)|go:"GO:0043219"(lateral loop)|go:"GO:0043311"(positive regulation of eosinophil degranulation)|go:"GO:0045202"(synapse)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0048278"(vesicle docking)|go:"GO:0048284"(organelle fusion)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048787"(presynaptic active zone membrane)|go:"GO:0050921"(positive regulation of chemotaxis)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1902041"(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1903575"(cornified envelope assembly)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|reactome:R-HSA-114516|reactome:R-HSA-1236974|reactome:R-HSA-1445148|reactome:R-HSA-199992|reactome:R-HSA-449836|interpro:IPR006011(Syntaxin, N-terminal)|refseq:NP_001259025.1	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Rwf+Olm3mXTGhh/KZUgtVel+wzc559292	rogid:NvOLGIGe/XO2aDPSpdPzrtKniZY9606	intact-crc:367F06831CAC41B8|rigid:h0WCNB/fcQEBEqbIlGx+UKyw0L8	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P53900	uniprotkb:Q12800	intact:EBI-13246|uniprotkb:D6W130|ensemblfungi:YNL153C	intact:EBI-717422|uniprotkb:Q12801|uniprotkb:Q9UD77|uniprotkb:A8K5E9|uniprotkb:Q9UD75|ensembl:ENSP00000257915	psi-mi:pfd4_yeast(display_long)|uniprotkb:GIM3(gene name)|psi-mi:GIM3(display_short)|uniprotkb:PFD4(gene name synonym)|uniprotkb:YNL153C(locus name)|uniprotkb:N1761(orf name)|uniprotkb:Genes involved in microtubule biogenesis protein 3(gene name synonym)|uniprotkb:Gim complex subunit 3(gene name synonym)	psi-mi:tfcp2_human(display_long)|uniprotkb:Transcription factor LSF(gene name synonym)|uniprotkb:SAA3 enhancer factor(gene name synonym)|uniprotkb:TFCP2(gene name)|psi-mi:TFCP2(display_short)|uniprotkb:LSF(gene name synonym)|uniprotkb:SEF(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551248|imex:IM-24995-3383	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014246.1|sgd:S000005097|mint:P53900|dip:DIP-3000N|ensemblfungi:YNL153C(gene)|ensemblfungi:YNL153C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:0015631"(tubulin binding)|go:"GO:0016272"(prefoldin complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0071629"(cytoplasm protein quality control by the ubiquitin-proteasome system)|interpro:IPR002777(Prefoldin beta-like)|interpro:IPR009053(Prefoldin)|interpro:IPR016661(Prefoldin, subunit 4)	refseq:NP_001166923.1|refseq:NP_001166924.1|refseq:NP_005644.2|ensembl:ENSG00000135457(gene)|ensembl:ENST00000257915(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR007604(CP2 transcription factor)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR037599|interpro:IPR041418|mint:Q12800	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:TdRDErsc5xwqaEqpI4SSCW0sCsg559292	rogid:M7mQ08NDYxuawmUEKRgjSdIr+Og9606	intact-crc:0B9F700C3C25FBD7|rigid:4kETE+1FpGLf+uZfabdDMW6BF5Y	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q12800	uniprotkb:P35184	intact:EBI-717422|uniprotkb:Q12801|uniprotkb:Q9UD77|uniprotkb:A8K5E9|uniprotkb:Q9UD75|ensembl:ENSP00000257915	intact:EBI-17971|uniprotkb:D6VVU2|ensemblfungi:YIR012W	psi-mi:tfcp2_human(display_long)|uniprotkb:Transcription factor LSF(gene name synonym)|uniprotkb:SAA3 enhancer factor(gene name synonym)|uniprotkb:TFCP2(gene name)|psi-mi:TFCP2(display_short)|uniprotkb:LSF(gene name synonym)|uniprotkb:SEF(gene name synonym)	psi-mi:sqt1_yeast(display_long)|uniprotkb:YIB12W(orf name)|uniprotkb:YIR012W(locus name)|uniprotkb:SQT1(gene name)|psi-mi:SQT1(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551256|imex:IM-24995-3385	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001166923.1|refseq:NP_001166924.1|refseq:NP_005644.2|ensembl:ENSG00000135457(gene)|ensembl:ENST00000257915(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR007604(CP2 transcription factor)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR037599|interpro:IPR041418|mint:Q12800	refseq:NP_012277.1|sgd:S000001451|ensemblfungi:YIR012W_mRNA(transcript)|ensemblfungi:YIR012W(gene)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|rcsb pdb:4ZOV|rcsb pdb:4ZOX|rcsb pdb:5AMS|dip:DIP-2508N|mint:P35184	-	-	crc64:981D566076B0C881	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:M7mQ08NDYxuawmUEKRgjSdIr+Og9606	rogid:u/Q5uAjR85ZD3op0nHiN20IVCLY559292	intact-crc:5CEE34772C8AE4C8|rigid:FMPTmQoz52SdPqULmpj3dGDYuNo	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q12800	uniprotkb:P40185	intact:EBI-717422|uniprotkb:Q12801|uniprotkb:Q9UD77|uniprotkb:A8K5E9|uniprotkb:Q9UD75|ensembl:ENSP00000257915	intact:EBI-11022|ensemblfungi:YIL051C|uniprotkb:D6VVN0	psi-mi:tfcp2_human(display_long)|uniprotkb:Transcription factor LSF(gene name synonym)|uniprotkb:SAA3 enhancer factor(gene name synonym)|uniprotkb:TFCP2(gene name)|psi-mi:TFCP2(display_short)|uniprotkb:LSF(gene name synonym)|uniprotkb:SEF(gene name synonym)	psi-mi:mmf1_yeast(display_long)|uniprotkb:MMF1(gene name)|psi-mi:MMF1(display_short)|uniprotkb:IBM1(gene name synonym)|uniprotkb:Maintenance of mitochondrial function 1(gene name synonym)|uniprotkb:Isoleucine biosynthesis and maintenance of intact mitochondria 1(gene name synonym)|uniprotkb:YIL051C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551252|imex:IM-24995-3384	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001166923.1|refseq:NP_001166924.1|refseq:NP_005644.2|ensembl:ENSG00000135457(gene)|ensembl:ENST00000257915(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR007604(CP2 transcription factor)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR037599|interpro:IPR041418|mint:Q12800	ensemblfungi:YIL051C(gene)|ensemblfungi:YIL051C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0009097"(isoleucine biosynthetic process)|go:"GO:0019239"(deaminase activity)|go:"GO:0032543"(mitochondrial translation)|go:"GO:1901565"(organonitrogen compound catabolic process)|interpro:IPR006056(YjgF-like protein)|interpro:IPR006175(Endoribonuclease L-PSP)|interpro:IPR019897|interpro:IPR035959|rcsb pdb:3QUW|refseq:NP_012213.3|sgd:S000001313|mint:P40185|dip:DIP-4714N	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:M7mQ08NDYxuawmUEKRgjSdIr+Og9606	rogid:N825kjK9jblhOOg4MZP7RmQXN1M559292	intact-crc:F2605A3AAB3D3E6E|rigid:nuT+IJit7wXV1lpOKf+gK5hVN+I	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q12800	uniprotkb:P25566	intact:EBI-717422|uniprotkb:Q12801|uniprotkb:Q9UD77|uniprotkb:A8K5E9|uniprotkb:Q9UD75|ensembl:ENSP00000257915	intact:EBI-21713|uniprotkb:D6VQY2|ensemblfungi:YCL033C	psi-mi:tfcp2_human(display_long)|uniprotkb:Transcription factor LSF(gene name synonym)|uniprotkb:SAA3 enhancer factor(gene name synonym)|uniprotkb:TFCP2(gene name)|psi-mi:TFCP2(display_short)|uniprotkb:LSF(gene name synonym)|uniprotkb:SEF(gene name synonym)	psi-mi:mxr2_yeast(display_long)|uniprotkb:YCL033C(locus name)|uniprotkb:YCL33C(orf name)|uniprotkb:MXR2(gene name)|psi-mi:MXR2(display_short)|uniprotkb:MSRB(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551260|imex:IM-24995-3386	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001166923.1|refseq:NP_001166924.1|refseq:NP_005644.2|ensembl:ENSG00000135457(gene)|ensembl:ENST00000257915(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR007604(CP2 transcription factor)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR037599|interpro:IPR041418|mint:Q12800	refseq:NP_009897.1|sgd:S000000538|dip:DIP-4861N|ensemblfungi:YCL033C(gene)|ensemblfungi:YCL033C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0030091"(protein repair)|go:"GO:0033743"("peptide-methionine (R)-S-oxide reductase activity")|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0046872"(metal ion binding)|interpro:IPR002579(Methionine sulphoxide reductase B)|interpro:IPR011057(Mss4-like)|interpro:IPR028427	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:M7mQ08NDYxuawmUEKRgjSdIr+Og9606	rogid:iqa3p6vw9Ah3pxugESw1TdFd6bU559292	intact-crc:A05A8124E68E6D00|rigid:T81VuNmA06E5rN2a8yPQld5qp7s	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P38340	uniprotkb:Q13049	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-742790|ensembl:ENSP00000363095|ensembl:ENSP00000408292|uniprotkb:Q9NQP8	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:tri32_human(display_long)|uniprotkb:Zinc finger protein HT2A(gene name synonym)|uniprotkb:72 kDa Tat-interacting protein(gene name synonym)|uniprotkb:TRIM32(gene name)|psi-mi:TRIM32(display_short)|uniprotkb:HT2A(gene name synonym)|uniprotkb:Tripartite motif-containing protein 32(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM32(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551288|imex:IM-24995-3393	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F	go:"GO:0043621"(protein self-association)|go:"GO:0045087"(innate immune response)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051155"(positive regulation of striated muscle cell differentiation)|go:"GO:0061564"(axon development)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1902187"|go:"GO:1902230"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:1903265"(positive regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:1903883"(positive regulation of interleukin-17-mediated signaling pathway)|go:"GO:1903886"("positive regulation of chemokine (C-C motif) ligand 20 production")|go:"GO:2000147"(positive regulation of cell motility)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENSG00000119401(gene)|ensembl:ENST00000373983(transcript)|ensembl:ENST00000450136(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001894"(tissue homeostasis)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005863"(striated muscle myosin thick filament)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007014"(actin ubiquitination)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009411"(response to UV)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0017022"(myosin binding)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030957"(Tat protein binding)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034612"(response to tumor necrosis factor)|go:"GO:0042802"(identical protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|interpro:IPR000315(Zinc finger, B-box)|refseq:NP_001093149.1|refseq:XP_011516700.1|refseq:NP_036342.2|refseq:XP_005251870.1|interpro:IPR001258(NHL repeat)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR013017(NHL repeat, subgroup)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR027370|mint:Q13049|rcsb pdb:2CT2|rcsb pdb:5FEY|reactome:R-HSA-3134975|reactome:R-HSA-983168|refseq:XP_016869975.1	-	crc64:66699F37B0013088	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:XuqprQd10kSpsuyGs+FSdzIdJ/Y9606	intact-crc:D5BAFEB0F7BA65E9|rigid:wrjCZrkmckE2GdnFZY8FI/59o0U	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q13049	uniprotkb:P38868	intact:EBI-742790|ensembl:ENSP00000363095|ensembl:ENSP00000408292|uniprotkb:Q9NQP8	intact:EBI-24840|uniprotkb:A0A1S0T004|ensemblfungi:YHR180W	psi-mi:tri32_human(display_long)|uniprotkb:Zinc finger protein HT2A(gene name synonym)|uniprotkb:72 kDa Tat-interacting protein(gene name synonym)|uniprotkb:TRIM32(gene name)|psi-mi:TRIM32(display_short)|uniprotkb:HT2A(gene name synonym)|uniprotkb:Tripartite motif-containing protein 32(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM32(gene name synonym)	psi-mi:yhy0_yeast(display_long)|uniprotkb:YHR180W(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551284|imex:IM-24995-3392	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0043621"(protein self-association)|go:"GO:0045087"(innate immune response)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051155"(positive regulation of striated muscle cell differentiation)|go:"GO:0061564"(axon development)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1902187"|go:"GO:1902230"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:1903265"(positive regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:1903883"(positive regulation of interleukin-17-mediated signaling pathway)|go:"GO:1903886"("positive regulation of chemokine (C-C motif) ligand 20 production")|go:"GO:2000147"(positive regulation of cell motility)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENSG00000119401(gene)|ensembl:ENST00000373983(transcript)|ensembl:ENST00000450136(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001894"(tissue homeostasis)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005863"(striated muscle myosin thick filament)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007014"(actin ubiquitination)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009411"(response to UV)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0017022"(myosin binding)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030957"(Tat protein binding)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034612"(response to tumor necrosis factor)|go:"GO:0042802"(identical protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|interpro:IPR000315(Zinc finger, B-box)|refseq:NP_001093149.1|refseq:XP_011516700.1|refseq:NP_036342.2|refseq:XP_005251870.1|interpro:IPR001258(NHL repeat)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR013017(NHL repeat, subgroup)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR027370|mint:Q13049|rcsb pdb:2CT2|rcsb pdb:5FEY|reactome:R-HSA-3134975|reactome:R-HSA-983168|refseq:XP_016869975.1	sgd:S000001223|dip:DIP-4332N|ensemblfungi:YHR180W(gene)|ensemblfungi:YHR180W_mRNA(transcript)|go:"GO:0016021"(integral component of membrane)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:XuqprQd10kSpsuyGs+FSdzIdJ/Y9606	rogid:E7zJN1iVyb08WvBGa7NXcqw4sqw559292	intact-crc:AE6A3CC9326E83D3|rigid:AjIWCkstYp9m6gL/ZjCq5bWK7gc	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P38736	uniprotkb:Q12846	intact:EBI-24365|uniprotkb:D3DKT7|ensemblfungi:YHL031C	intact:EBI-744942|uniprotkb:Q15525|ensembl:ENSP00000317714|uniprotkb:Q6FHE8|uniprotkb:A8MXY0	psi-mi:gosr1_yeast(display_long)|uniprotkb:Golgi SNARE protein 1(gene name synonym)|uniprotkb:GOS1(gene name)|psi-mi:GOS1(display_short)|uniprotkb:Protein transport protein GOS1(gene name synonym)|uniprotkb:YHL031C(locus name)	psi-mi:stx4_human(display_long)|uniprotkb:Renal carcinoma antigen NY-REN-31(gene name synonym)|uniprotkb:STX4(gene name)|psi-mi:STX4(display_short)|uniprotkb:STX4A(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551272|imex:IM-24995-3389	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011832.1|sgd:S000001023|reactome:R-SCE-6811438|dip:DIP-2490N|reactome:R-SCE-6807878|ensemblfungi:YHL031C(gene)|ensemblfungi:YHL031C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005797"(Golgi medial cisterna)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0048193"(Golgi vesicle transport)|go:"GO:0048209"(regulation of vesicle targeting, to, from or within Golgi)|interpro:IPR023601|go:"GO:0006906"(vesicle fusion)	ensembl:ENSG00000103496(gene)|refseq:NP_004595.2|ensembl:ENST00000313843(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0000322"(storage vacuole)|go:"GO:0002639"(positive regulation of immunoglobulin production)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005768"(endosome)|go:"GO:0005773"(vacuole)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006887"(exocytosis)|go:"GO:0006906"(vesicle fusion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016230"(sphingomyelin phosphodiesterase activator activity)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0032589"(neuron projection membrane)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035493"(SNARE complex assembly)|go:"GO:0035749"(myelin sheath adaxonal region)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0036477"(somatodendritic compartment)|go:"GO:0042581"(specific granule)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043197"(dendritic spine)|go:"GO:0043219"(lateral loop)|go:"GO:0043311"(positive regulation of eosinophil degranulation)|go:"GO:0045202"(synapse)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0048278"(vesicle docking)|go:"GO:0048284"(organelle fusion)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048787"(presynaptic active zone membrane)|go:"GO:0050921"(positive regulation of chemotaxis)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1902041"(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1903575"(cornified envelope assembly)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|reactome:R-HSA-114516|reactome:R-HSA-1236974|reactome:R-HSA-1445148|reactome:R-HSA-199992|reactome:R-HSA-449836|interpro:IPR006011(Syntaxin, N-terminal)|refseq:NP_001259025.1	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:pAzDzV46XXzIOB4p/oc1PlMc54E559292	rogid:NvOLGIGe/XO2aDPSpdPzrtKniZY9606	intact-crc:DC1B66876C3C50FD|rigid:szKyYXHC1lWBdl3DK2CWB+V8uW8	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P38182	uniprotkb:Q12983	intact:EBI-2684|uniprotkb:D6VPS5|ensemblfungi:YBL078C	intact:EBI-749464|uniprotkb:O14620|uniprotkb:Q96GP0|intact:EBI-28978130|ensembl:ENSP00000357625	psi-mi:atg8_yeast(display_long)|uniprotkb:ATG8(gene name)|psi-mi:ATG8(display_short)|uniprotkb:APG8(gene name synonym)|uniprotkb:AUT7(gene name synonym)|uniprotkb:YBL078C(locus name)|uniprotkb:YBL0732(orf name)|uniprotkb:CVT5(gene name synonym)|uniprotkb:Autophagy-related ubiquitin-like modifier ATG8(gene name synonym)|uniprotkb:Cytoplasm to vacuole targeting protein 5(gene name synonym)	psi-mi:bnip3_human(display_long)|uniprotkb:BNIP3(gene name)|psi-mi:BNIP3(display_short)|uniprotkb:NIP3(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551276|imex:IM-24995-3390	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000000174|refseq:NP_009475.1|dip:DIP-1197N|mint:P38182|ensemblfungi:YBL078C(gene)|ensemblfungi:YBL078C_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006914"(autophagy)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0008429"(phosphatidylethanolamine binding)|go:"GO:0016236"(macroautophagy)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0031386"(protein tag)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0033110"(Cvt vesicle membrane)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0034629"|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|go:"GO:0061025"(membrane fusion)|go:"GO:0061709"(reticulophagy)|go:"GO:0071211"(protein targeting to vacuole involved in autophagy)|go:"GO:0120095"(vacuole-isolation membrane contact site)|go:"GO:1905153"(regulation of membrane invagination)|interpro:IPR004241("Light chain 3 (LC3)")|interpro:IPR029071|rcsb pdb:2KQ7|rcsb pdb:2KWC|rcsb pdb:2LI5|rcsb pdb:2ZPN|rcsb pdb:3RUI|rcsb pdb:3VH3|rcsb pdb:3VH4|rcsb pdb:3VXW|rcsb pdb:5YEC|rcsb pdb:6AAG|rcsb pdb:6WY6|rcsb pdb:7BRN|reactome:R-SCE-1632852|reactome:R-SCE-8854214|reactome:R-SCE-8934903	ensembl:ENSP00000357625|refseq:NP_004043.3|dip:DIP-34429N|ensembl:ENSG00000176171(gene)|ensembl:ENST00000368636(transcript)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006915"(apoptotic process)|go:"GO:0008219"(cell death)|go:"GO:0009617"(response to bacterium)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010637"(negative regulation of mitochondrial fusion)|go:"GO:0010659"(cardiac muscle cell apoptotic process)|go:"GO:0010666"(positive regulation of cardiac muscle cell apoptotic process)|go:"GO:0010917"(negative regulation of mitochondrial membrane potential)|go:"GO:0010940"(positive regulation of necrotic cell death)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030425"(dendrite)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0035694"(mitochondrial protein catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043067"(regulation of programmed cell death)|go:"GO:0043068"(positive regulation of programmed cell death)|go:"GO:0043243"(positive regulation of protein-containing complex disassembly)|go:"GO:0043653"(mitochondrial fragmentation involved in apoptotic process)|go:"GO:0045837"(negative regulation of membrane potential)|go:"GO:0046902"(regulation of mitochondrial membrane permeability)|go:"GO:0048102"(autophagic cell death)|go:"GO:0048678"(response to axon injury)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0050873"(brown fat cell differentiation)|go:"GO:0051020"(GTPase binding)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051561"(positive regulation of mitochondrial calcium ion concentration)|go:"GO:0051607"(defense response to virus)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071279"(cellular response to cobalt ion)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|go:"GO:0090649"(response to oxygen-glucose deprivation)|go:"GO:0097345"(mitochondrial outer membrane permeabilization)|go:"GO:0140507"(granzyme-mediated programmed cell death signaling pathway)|go:"GO:1901998"(toxin transport)|go:"GO:1902109"(negative regulation of mitochondrial membrane permeability involved in apoptotic process)|go:"GO:1903599"(positive regulation of autophagy of mitochondrion)|go:"GO:1903715"(regulation of aerobic respiration)|go:"GO:1990144"(intrinsic apoptotic signaling pathway in response to hypoxia)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|interpro:IPR010548(BNIP3)|mint:Q12983|rcsb pdb:2J5D|rcsb pdb:2KA1|rcsb pdb:2KA2	-	crc64:1246CEFF5A038819	crc64:53967696EDA005E2	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2017/06/28	rogid:UlmpBW3JgdYFHLkZCQeJeb7DpK4559292	rogid:f+opYD7xO+AbYqLXXC5wh4ZJqIE9606	intact-crc:C387DAF2A3FD9AEA|rigid:E/j5dg5KUIp1NpkVYjNR0weuIE0	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P32502	uniprotkb:Q13049	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	intact:EBI-742790|ensembl:ENSP00000363095|ensembl:ENSP00000408292|uniprotkb:Q9NQP8	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:tri32_human(display_long)|uniprotkb:Zinc finger protein HT2A(gene name synonym)|uniprotkb:72 kDa Tat-interacting protein(gene name synonym)|uniprotkb:TRIM32(gene name)|psi-mi:TRIM32(display_short)|uniprotkb:HT2A(gene name synonym)|uniprotkb:Tripartite motif-containing protein 32(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM32(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551280|imex:IM-24995-3391	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731	go:"GO:0043621"(protein self-association)|go:"GO:0045087"(innate immune response)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051155"(positive regulation of striated muscle cell differentiation)|go:"GO:0061564"(axon development)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1902187"|go:"GO:1902230"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:1903265"(positive regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:1903883"(positive regulation of interleukin-17-mediated signaling pathway)|go:"GO:1903886"("positive regulation of chemokine (C-C motif) ligand 20 production")|go:"GO:2000147"(positive regulation of cell motility)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENSG00000119401(gene)|ensembl:ENST00000373983(transcript)|ensembl:ENST00000450136(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001894"(tissue homeostasis)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005863"(striated muscle myosin thick filament)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007014"(actin ubiquitination)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009411"(response to UV)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0017022"(myosin binding)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030957"(Tat protein binding)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034612"(response to tumor necrosis factor)|go:"GO:0042802"(identical protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|interpro:IPR000315(Zinc finger, B-box)|refseq:NP_001093149.1|refseq:XP_011516700.1|refseq:NP_036342.2|refseq:XP_005251870.1|interpro:IPR001258(NHL repeat)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR013017(NHL repeat, subgroup)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR027370|mint:Q13049|rcsb pdb:2CT2|rcsb pdb:5FEY|reactome:R-HSA-3134975|reactome:R-HSA-983168|refseq:XP_016869975.1	-	crc64:A5409FAF1594854C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	rogid:XuqprQd10kSpsuyGs+FSdzIdJ/Y9606	intact-crc:F37710EE917D5110|rigid:rHcMBkLR5Rdd3LnDcpJZingk8vU	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q13137	uniprotkb:Q02821	intact:EBI-739580|uniprotkb:B4DDC4|uniprotkb:E7ENK0|uniprotkb:Q53FQ5|uniprotkb:Q53HB5|uniprotkb:Q6IBN9|uniprotkb:Q9BTF7|uniprotkb:B2RBT0|ensembl:ENSP00000258947|uniprotkb:B4E0C0|uniprotkb:E7ETP5|uniprotkb:B4DDT4|uniprotkb:B4DP36|uniprotkb:E9PBE5	intact:EBI-1797|uniprotkb:D6W0Z8|ensemblfungi:YNL189W	psi-mi:caco2_human(display_long)|uniprotkb:CALCOCO2(gene name)|psi-mi:CALCOCO2(display_short)|uniprotkb:NDP52(gene name synonym)|uniprotkb:Nuclear domain 10 protein NDP52(gene name synonym)|uniprotkb:Antigen nuclear dot 52 kDa protein(gene name synonym)|uniprotkb:Nuclear dot protein 52(gene name synonym)	psi-mi:ima1_yeast(display_long)|uniprotkb:SRP1(gene name)|psi-mi:SRP1(display_short)|uniprotkb:KAP60(gene name synonym)|uniprotkb:YNL189W(locus name)|uniprotkb:N1606(orf name)|uniprotkb:Karyopherin subunit alpha(gene name synonym)|uniprotkb:Karyopherin-60(gene name synonym)|uniprotkb:Serine-rich RNA polymerase I suppressor protein(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551312|imex:IM-24995-3399	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001248319.1|refseq:NP_001248320.1|refseq:NP_001248322.1|refseq:NP_005822.1|ensembl:ENSG00000136436(gene)|ensembl:ENST00000258947(transcript)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016032"(viral process)|go:"GO:0016605"(PML body)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0098792"(xenophagy)|go:"GO:1901098"(positive regulation of autophagosome maturation)|interpro:IPR041611|interpro:IPR041641|mint:Q13137|rcsb pdb:2MXP|rcsb pdb:3VVV|rcsb pdb:3VVW|rcsb pdb:4GXL|rcsb pdb:4HAN|rcsb pdb:4XKL|rcsb pdb:5AAQ|rcsb pdb:5Z7A|rcsb pdb:5Z7L|refseq:NP_001248324.1|dip:DIP-57534N	refseq:NP_014210.1|sgd:S000005133|dip:DIP-728N|mint:Q02821|ensemblfungi:YNL189W(gene)|ensemblfungi:YNL189W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0031144"(proteasome localization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042564"(NLS-dependent protein nuclear import complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|rcsb pdb:1BK5|rcsb pdb:1BK6|rcsb pdb:1EE4|rcsb pdb:1EE5|rcsb pdb:1UN0|rcsb pdb:1WA5|rcsb pdb:2C1T|rcsb pdb:4PVZ|rcsb pdb:4XZR|rcsb pdb:5H2W|rcsb pdb:5H2X|rcsb pdb:5T94	-	crc64:609B121DA1A9DCB8	crc64:8D3A0CB76F2E7C00	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:N/GPJUGBK+Dh5Cg+csmafphuo9M9606	rogid:NyzC93xnBCb8DX/AH346lwg4u2A559292	intact-crc:B0A9775023E0DDA6|rigid:hHMSqSo0VC7VlXnaDmX0YbMFn94	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P39518	uniprotkb:Q13137	intact:EBI-10082|uniprotkb:D3DLR3|ensemblfungi:YER015W	intact:EBI-739580|uniprotkb:B4DDC4|uniprotkb:E7ENK0|uniprotkb:Q53FQ5|uniprotkb:Q53HB5|uniprotkb:Q6IBN9|uniprotkb:Q9BTF7|uniprotkb:B2RBT0|ensembl:ENSP00000258947|uniprotkb:B4E0C0|uniprotkb:E7ETP5|uniprotkb:B4DDT4|uniprotkb:B4DP36|uniprotkb:E9PBE5	psi-mi:lcf2_yeast(display_long)|uniprotkb:YER015W(locus name)|uniprotkb:FAA2(gene name)|psi-mi:FAA2(display_short)|uniprotkb:FAM1(gene name synonym)|uniprotkb:Long-chain acyl-CoA synthetase 2(gene name synonym)|uniprotkb:Fatty acid activator 2(gene name synonym)	psi-mi:caco2_human(display_long)|uniprotkb:CALCOCO2(gene name)|psi-mi:CALCOCO2(display_short)|uniprotkb:NDP52(gene name synonym)|uniprotkb:Nuclear domain 10 protein NDP52(gene name synonym)|uniprotkb:Antigen nuclear dot 52 kDa protein(gene name synonym)|uniprotkb:Nuclear dot protein 52(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551308|imex:IM-24995-3398	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000000817|ensemblfungi:YER015W_mRNA(transcript)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0004467"(long-chain fatty acid-CoA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0015910"(long-chain fatty acid import into peroxisome)|go:"GO:0015916"(fatty-acyl-CoA transport)|go:"GO:0016020"(membrane)|go:"GO:0031956"(medium-chain fatty acid-CoA ligase activity)|go:"GO:0031957"(very long-chain fatty acid-CoA ligase activity)|go:"GO:0042760"(very long-chain fatty acid catabolic process)|go:"GO:0102391"(decanoate-CoA ligase activity)|ensemblfungi:YER015W(gene)|interpro:IPR020845|interpro:IPR000873(AMP-dependent synthetase and ligase)|reactome:R-SCE-75876|refseq:NP_010931.3|dip:DIP-6565N	refseq:NP_001248319.1|refseq:NP_001248320.1|refseq:NP_001248322.1|refseq:NP_005822.1|ensembl:ENSG00000136436(gene)|ensembl:ENST00000258947(transcript)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016032"(viral process)|go:"GO:0016605"(PML body)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0098792"(xenophagy)|go:"GO:1901098"(positive regulation of autophagosome maturation)|interpro:IPR041611|interpro:IPR041641|mint:Q13137|rcsb pdb:2MXP|rcsb pdb:3VVV|rcsb pdb:3VVW|rcsb pdb:4GXL|rcsb pdb:4HAN|rcsb pdb:4XKL|rcsb pdb:5AAQ|rcsb pdb:5Z7A|rcsb pdb:5Z7L|refseq:NP_001248324.1|dip:DIP-57534N	-	crc64:1E023C18682805BC	crc64:609B121DA1A9DCB8	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:N0W+wPvCsl01y0k8hJZ156LztOo559292	rogid:N/GPJUGBK+Dh5Cg+csmafphuo9M9606	intact-crc:E9743FBB5244C9BB|rigid:JuBP4SQdwbjIksL/sT7y/Ft556A	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q13049	uniprotkb:P40070	intact:EBI-742790|ensembl:ENSP00000363095|ensembl:ENSP00000408292|uniprotkb:Q9NQP8	intact:EBI-188|uniprotkb:Q07091|uniprotkb:D3DM18|ensemblfungi:YER112W	psi-mi:tri32_human(display_long)|uniprotkb:Zinc finger protein HT2A(gene name synonym)|uniprotkb:72 kDa Tat-interacting protein(gene name synonym)|uniprotkb:TRIM32(gene name)|psi-mi:TRIM32(display_short)|uniprotkb:HT2A(gene name synonym)|uniprotkb:Tripartite motif-containing protein 32(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM32(gene name synonym)	psi-mi:lsm4_yeast(display_long)|uniprotkb:LSM4(gene name)|psi-mi:LSM4(display_short)|uniprotkb:SDB23(gene name synonym)|uniprotkb:USS1(gene name synonym)|uniprotkb:YER112W(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551292|imex:IM-24995-3394	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0043621"(protein self-association)|go:"GO:0045087"(innate immune response)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051155"(positive regulation of striated muscle cell differentiation)|go:"GO:0061564"(axon development)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1902187"|go:"GO:1902230"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:1903265"(positive regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:1903883"(positive regulation of interleukin-17-mediated signaling pathway)|go:"GO:1903886"("positive regulation of chemokine (C-C motif) ligand 20 production")|go:"GO:2000147"(positive regulation of cell motility)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENSG00000119401(gene)|ensembl:ENST00000373983(transcript)|ensembl:ENST00000450136(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001894"(tissue homeostasis)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005863"(striated muscle myosin thick filament)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007014"(actin ubiquitination)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009411"(response to UV)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0017022"(myosin binding)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030957"(Tat protein binding)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034612"(response to tumor necrosis factor)|go:"GO:0042802"(identical protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|interpro:IPR000315(Zinc finger, B-box)|refseq:NP_001093149.1|refseq:XP_011516700.1|refseq:NP_036342.2|refseq:XP_005251870.1|interpro:IPR001258(NHL repeat)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR013017(NHL repeat, subgroup)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR027370|mint:Q13049|rcsb pdb:2CT2|rcsb pdb:5FEY|reactome:R-HSA-3134975|reactome:R-HSA-983168|refseq:XP_016869975.1	sgd:S000000914|refseq:NP_011037.3|mint:P40070|dip:DIP-848N|ensemblfungi:YER112W(gene)|ensemblfungi:YER112W_mRNA(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000932"(P-body)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005688"(U6 snRNP)|go:"GO:0005730"(nucleolus)|go:"GO:0005732"("sno(s)RNA-containing ribonucleoprotein complex")|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0008033"(tRNA processing)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0033962"(P-body assembly)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0097526"(spliceosomal tri-snRNP complex)|go:"GO:1990726"(Lsm1-7-Pat1 complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR027141|interpro:IPR034101|rcsb pdb:3JCM|rcsb pdb:4C8Q|rcsb pdb:4C92|rcsb pdb:4M75|rcsb pdb:4M77|rcsb pdb:4M78|rcsb pdb:4M7A|rcsb pdb:4M7D|rcsb pdb:5GAN|rcsb pdb:5NRL|rcsb pdb:5VSU|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:6ASO|reactome:R-SCE-430039	-	-	crc64:69CAC1F01D5BFA98	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:XuqprQd10kSpsuyGs+FSdzIdJ/Y9606	rogid:Sz8HLaybwgxCRbeCESby3YThqeM559292	intact-crc:000ADC748CC3E043|rigid:e+QfnPkpuY4D6PAkml9j4dlL/tg	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q07821	uniprotkb:Q13137	intact:EBI-27136|uniprotkb:D6VXX7|ensemblfungi:YLL027W	intact:EBI-739580|uniprotkb:B4DDC4|uniprotkb:E7ENK0|uniprotkb:Q53FQ5|uniprotkb:Q53HB5|uniprotkb:Q6IBN9|uniprotkb:Q9BTF7|uniprotkb:B2RBT0|ensembl:ENSP00000258947|uniprotkb:B4E0C0|uniprotkb:E7ETP5|uniprotkb:B4DDT4|uniprotkb:B4DP36|uniprotkb:E9PBE5	psi-mi:isa1_yeast(display_long)|uniprotkb:YLL027W(locus name)|uniprotkb:ISA1(gene name)|psi-mi:ISA1(display_short)	psi-mi:caco2_human(display_long)|uniprotkb:CALCOCO2(gene name)|psi-mi:CALCOCO2(display_short)|uniprotkb:NDP52(gene name synonym)|uniprotkb:Nuclear domain 10 protein NDP52(gene name synonym)|uniprotkb:Antigen nuclear dot 52 kDa protein(gene name synonym)|uniprotkb:Nuclear dot protein 52(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551300|imex:IM-24995-3396	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013073.1|sgd:S000003950|mint:Q07821|dip:DIP-1394N|ensemblfungi:YLL027W(gene)|ensemblfungi:YLL027W_mRNA(transcript)|go:"GO:0005506"(iron ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0009102"(biotin biosynthetic process)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0051536"(iron-sulfur cluster binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|go:"GO:0106035"(protein maturation by [4Fe-4S] cluster transfer)|interpro:IPR000361(HesB/YadR/YfhF-like)|interpro:IPR016092(HesB/YadR/YfhF)|interpro:IPR017870|interpro:IPR035903|reactome:R-SCE-1362409	refseq:NP_001248319.1|refseq:NP_001248320.1|refseq:NP_001248322.1|refseq:NP_005822.1|ensembl:ENSG00000136436(gene)|ensembl:ENST00000258947(transcript)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016032"(viral process)|go:"GO:0016605"(PML body)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0098792"(xenophagy)|go:"GO:1901098"(positive regulation of autophagosome maturation)|interpro:IPR041611|interpro:IPR041641|mint:Q13137|rcsb pdb:2MXP|rcsb pdb:3VVV|rcsb pdb:3VVW|rcsb pdb:4GXL|rcsb pdb:4HAN|rcsb pdb:4XKL|rcsb pdb:5AAQ|rcsb pdb:5Z7A|rcsb pdb:5Z7L|refseq:NP_001248324.1|dip:DIP-57534N	-	crc64:226C286B4F80DE6D	crc64:609B121DA1A9DCB8	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:QD74jkP7pZD875xxXj5J2YPKb5g559292	rogid:N/GPJUGBK+Dh5Cg+csmafphuo9M9606	intact-crc:4D2D79D1AB0E51B5|rigid:/QlFAJZFEm1z8taqFaGOjmznxy4	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q13137	uniprotkb:Q12342	intact:EBI-739580|uniprotkb:B4DDC4|uniprotkb:E7ENK0|uniprotkb:Q53FQ5|uniprotkb:Q53HB5|uniprotkb:Q6IBN9|uniprotkb:Q9BTF7|uniprotkb:B2RBT0|ensembl:ENSP00000258947|uniprotkb:B4E0C0|uniprotkb:E7ETP5|uniprotkb:B4DDT4|uniprotkb:B4DP36|uniprotkb:E9PBE5	intact:EBI-38872|uniprotkb:D6VRK2|ensemblfungi:YDL146W	psi-mi:caco2_human(display_long)|uniprotkb:CALCOCO2(gene name)|psi-mi:CALCOCO2(display_short)|uniprotkb:NDP52(gene name synonym)|uniprotkb:Nuclear domain 10 protein NDP52(gene name synonym)|uniprotkb:Antigen nuclear dot 52 kDa protein(gene name synonym)|uniprotkb:Nuclear dot protein 52(gene name synonym)	psi-mi:ldb17_yeast(display_long)|uniprotkb:Low dye-binding protein 17(gene name synonym)|uniprotkb:LDB17(gene name)|psi-mi:LDB17(display_short)|uniprotkb:D1575(orf name)|uniprotkb:YDL146W(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551296|imex:IM-24995-3395	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001248319.1|refseq:NP_001248320.1|refseq:NP_001248322.1|refseq:NP_005822.1|ensembl:ENSG00000136436(gene)|ensembl:ENST00000258947(transcript)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016032"(viral process)|go:"GO:0016605"(PML body)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0098792"(xenophagy)|go:"GO:1901098"(positive regulation of autophagosome maturation)|interpro:IPR041611|interpro:IPR041641|mint:Q13137|rcsb pdb:2MXP|rcsb pdb:3VVV|rcsb pdb:3VVW|rcsb pdb:4GXL|rcsb pdb:4HAN|rcsb pdb:4XKL|rcsb pdb:5AAQ|rcsb pdb:5Z7A|rcsb pdb:5Z7L|refseq:NP_001248324.1|dip:DIP-57534N	refseq:NP_010135.1|sgd:S000002305|dip:DIP-1803N|ensemblfungi:YDL146W(gene)|ensemblfungi:YDL146W_mRNA(transcript)|go:"GO:0000147"(actin cortical patch assembly)|go:"GO:0005737"(cytoplasm)|go:"GO:0005933"(cellular bud)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006897"(endocytosis)|go:"GO:0017022"(myosin binding)|go:"GO:0030479"(actin cortical patch)|go:"GO:0051666"(actin cortical patch localization)|go:"GO:0071933"(Arp2/3 complex binding)|interpro:IPR018556|interpro:IPR030125	-	crc64:609B121DA1A9DCB8	crc64:608DED6598F054BD	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:N/GPJUGBK+Dh5Cg+csmafphuo9M9606	rogid:o1oe+zL8FJ90xm43hCM9A7lGCjI559292	intact-crc:93CC8968F481CB6E|rigid:VVJMZbTKuZ9FvwMTkTANwYJt7ww	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P32902	uniprotkb:Q13137	intact:EBI-16248|ensemblfungi:YHL004W|uniprotkb:D3DKR0	intact:EBI-739580|uniprotkb:B4DDC4|uniprotkb:E7ENK0|uniprotkb:Q53FQ5|uniprotkb:Q53HB5|uniprotkb:Q6IBN9|uniprotkb:Q9BTF7|uniprotkb:B2RBT0|ensembl:ENSP00000258947|uniprotkb:B4E0C0|uniprotkb:E7ETP5|uniprotkb:B4DDT4|uniprotkb:B4DP36|uniprotkb:E9PBE5	psi-mi:rt04_yeast(display_long)|uniprotkb:MRP4(gene name)|psi-mi:MRP4(display_short)|uniprotkb:MRP4A(gene name synonym)|uniprotkb:Mitochondrial small ribosomal subunit protein uS2m(gene name synonym)|uniprotkb:YHL004W(locus name)	psi-mi:caco2_human(display_long)|uniprotkb:CALCOCO2(gene name)|psi-mi:CALCOCO2(display_short)|uniprotkb:NDP52(gene name synonym)|uniprotkb:Nuclear domain 10 protein NDP52(gene name synonym)|uniprotkb:Antigen nuclear dot 52 kDa protein(gene name synonym)|uniprotkb:Nuclear dot protein 52(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551304|imex:IM-24995-3397	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YHL004W(gene)|ensemblfungi:YHL004W_mRNA(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR001865(Ribosomal protein S2)|interpro:IPR005706(Ribosomal protein S2, bacterial-type)|interpro:IPR018130|interpro:IPR023591|rcsb pdb:5MRC|rcsb pdb:5MRE|rcsb pdb:5MRF|refseq:NP_011859.1|sgd:S000000996|dip:DIP-5035N|mint:P32902	refseq:NP_001248319.1|refseq:NP_001248320.1|refseq:NP_001248322.1|refseq:NP_005822.1|ensembl:ENSG00000136436(gene)|ensembl:ENST00000258947(transcript)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016032"(viral process)|go:"GO:0016605"(PML body)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0098792"(xenophagy)|go:"GO:1901098"(positive regulation of autophagosome maturation)|interpro:IPR041611|interpro:IPR041641|mint:Q13137|rcsb pdb:2MXP|rcsb pdb:3VVV|rcsb pdb:3VVW|rcsb pdb:4GXL|rcsb pdb:4HAN|rcsb pdb:4XKL|rcsb pdb:5AAQ|rcsb pdb:5Z7A|rcsb pdb:5Z7L|refseq:NP_001248324.1|dip:DIP-57534N	-	crc64:81A1CB33134BC559	crc64:609B121DA1A9DCB8	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:BlL3W6HUN+uAKF/AxwlV1zT5YZQ559292	rogid:N/GPJUGBK+Dh5Cg+csmafphuo9M9606	intact-crc:109082F759B76C10|rigid:4ZnZLADDPmSwFQZcdVxBb3YFxqI	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P41911	uniprotkb:Q13137	intact:EBI-7791|uniprotkb:P50905|uniprotkb:D6W208|ensemblfungi:YOL059W	intact:EBI-739580|uniprotkb:B4DDC4|uniprotkb:E7ENK0|uniprotkb:Q53FQ5|uniprotkb:Q53HB5|uniprotkb:Q6IBN9|uniprotkb:Q9BTF7|uniprotkb:B2RBT0|ensembl:ENSP00000258947|uniprotkb:B4E0C0|uniprotkb:E7ETP5|uniprotkb:B4DDT4|uniprotkb:B4DP36|uniprotkb:E9PBE5	psi-mi:gpd2_yeast(display_long)|uniprotkb:GPD2(gene name)|psi-mi:GPD2(display_short)|uniprotkb:GPD3(gene name synonym)|uniprotkb:YOL059W(locus name)|uniprotkb:O1222(orf name)	psi-mi:caco2_human(display_long)|uniprotkb:CALCOCO2(gene name)|psi-mi:CALCOCO2(display_short)|uniprotkb:NDP52(gene name synonym)|uniprotkb:Nuclear domain 10 protein NDP52(gene name synonym)|uniprotkb:Antigen nuclear dot 52 kDa protein(gene name synonym)|uniprotkb:Nuclear dot protein 52(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551332|imex:IM-24995-3404	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014582.1|sgd:S000005420|dip:DIP-1348N|mint:P41911|ensemblfungi:YOL059W(gene)|ensemblfungi:YOL059W_mRNA(transcript)|go:"GO:0004367"(glycerol-3-phosphate dehydrogenase [NAD+] activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006071"(glycerol metabolic process)|go:"GO:0006072"(glycerol-3-phosphate metabolic process)|go:"GO:0006116"(NADH oxidation)|go:"GO:0009331"(glycerol-3-phosphate dehydrogenase complex)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046168"(glycerol-3-phosphate catabolic process)|go:"GO:0051287"(NAD binding)|interpro:IPR006109(NAD-dependent glycerol-3-phosphate dehydrogenase, C-terminal)|interpro:IPR006168(NAD-dependent glycerol-3-phosphate dehydrogenase)|interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|interpro:IPR011128(NAD-dependent glycerol-3-phosphate dehydrogenase, N-terminal)|interpro:IPR013328(Dehydrogenase, multihelical)|interpro:IPR017751(NAD-dependent glycerol-3-phosphate dehydrogenase, eukaryotic)|interpro:IPR036291|reactome:R-SCE-1483166	refseq:NP_001248319.1|refseq:NP_001248320.1|refseq:NP_001248322.1|refseq:NP_005822.1|ensembl:ENSG00000136436(gene)|ensembl:ENST00000258947(transcript)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016032"(viral process)|go:"GO:0016605"(PML body)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0098792"(xenophagy)|go:"GO:1901098"(positive regulation of autophagosome maturation)|interpro:IPR041611|interpro:IPR041641|mint:Q13137|rcsb pdb:2MXP|rcsb pdb:3VVV|rcsb pdb:3VVW|rcsb pdb:4GXL|rcsb pdb:4HAN|rcsb pdb:4XKL|rcsb pdb:5AAQ|rcsb pdb:5Z7A|rcsb pdb:5Z7L|refseq:NP_001248324.1|dip:DIP-57534N	-	crc64:FA6C07034D3EC720	crc64:609B121DA1A9DCB8	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:RX8TddHnpQdQdh6KN8y9IR8Jgrg559292	rogid:N/GPJUGBK+Dh5Cg+csmafphuo9M9606	intact-crc:35DD2CFE895B9FDB|rigid:3CRaXf3nmzXRGwe6e1gllePohpw	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P05759	uniprotkb:Q13137	intact:EBI-16127|uniprotkb:P14800|ensemblfungi:YLR167W|uniprotkb:D6VYH3|uniprotkb:P04838|uniprotkb:P61864|uniprotkb:Q6LA96	intact:EBI-739580|uniprotkb:B4DDC4|uniprotkb:E7ENK0|uniprotkb:Q53FQ5|uniprotkb:Q53HB5|uniprotkb:Q6IBN9|uniprotkb:Q9BTF7|uniprotkb:B2RBT0|ensembl:ENSP00000258947|uniprotkb:B4E0C0|uniprotkb:E7ETP5|uniprotkb:B4DDT4|uniprotkb:B4DP36|uniprotkb:E9PBE5	psi-mi:rs31_yeast(display_long)|uniprotkb:RPS31(gene name)|psi-mi:RPS31(display_short)|uniprotkb:UBI3(gene name synonym)|uniprotkb:YLR167W(locus name)|uniprotkb:L9470.14(orf name)|uniprotkb:RPS37(gene name synonym)	psi-mi:caco2_human(display_long)|uniprotkb:CALCOCO2(gene name)|psi-mi:CALCOCO2(display_short)|uniprotkb:NDP52(gene name synonym)|uniprotkb:Nuclear domain 10 protein NDP52(gene name synonym)|uniprotkb:Antigen nuclear dot 52 kDa protein(gene name synonym)|uniprotkb:Nuclear dot protein 52(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551328|imex:IM-24995-3403	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:6WOO|rcsb pdb:6Z6J|rcsb pdb:6Z6K|rcsb pdb:6ZCE|rcsb pdb:6ZQH|rcsb pdb:6ZU9|rcsb pdb:6ZVI|rcsb pdb:7A1G|rcsb pdb:7B7D|rcsb pdb:7NRC|rcsb pdb:7NRD|rcsb pdb:5WYJ|rcsb pdb:6EML|rcsb pdb:6GQ1|rcsb pdb:6GQB|rcsb pdb:6GQV|rcsb pdb:6HHQ|rcsb pdb:6I7O|rcsb pdb:6Q8Y|rcsb pdb:6RBE|rcsb pdb:6S47|rcsb pdb:6SNT|rcsb pdb:6SV4|rcsb pdb:6T4Q|rcsb pdb:6T7I|rcsb pdb:6T7T|rcsb pdb:6T83|rcsb pdb:6TB3|rcsb pdb:6TNU|rcsb pdb:6WDR|ensemblfungi:YLR167W(gene)|ensemblfungi:YLR167W_mRNA(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0002109"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, LSU-rRNA,5S)")|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0031386"(protein tag)|rcsb pdb:4U56|rcsb pdb:4U6F|rcsb pdb:4V88|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0046872"(metal ion binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR002906(Ribosomal protein S27a)|interpro:IPR011332(Ribosomal protein, zinc-binding)|interpro:IPR019954|interpro:IPR019956|interpro:IPR029071|rcsb pdb:4V8Y|interpro:IPR038582|rcsb pdb:3J6X|rcsb pdb:3J6Y|rcsb pdb:3J77|rcsb pdb:4V8Z|rcsb pdb:3J78|rcsb pdb:4U3M|rcsb pdb:4U3N|rcsb pdb:4U3U|rcsb pdb:4U4N|rcsb pdb:4U4O|rcsb pdb:4U4Q|rcsb pdb:4U4R|rcsb pdb:4U4U|rcsb pdb:4U4Y|rcsb pdb:4U4Z|rcsb pdb:4U50|rcsb pdb:4U51|rcsb pdb:4U52|rcsb pdb:4U53|rcsb pdb:4U55|rcsb pdb:4V92|rcsb pdb:5DAT|rcsb pdb:5DC3|rcsb pdb:5DGE|rcsb pdb:5DGF|rcsb pdb:5DGV|rcsb pdb:5FCI|rcsb pdb:5FCJ|rcsb pdb:5I4L|rcsb pdb:5JUO|rcsb pdb:5JUP|rcsb pdb:5JUS|rcsb pdb:5JUT|rcsb pdb:5JUU|rcsb pdb:5L6H|rcsb pdb:5L6I|rcsb pdb:5L6J|rcsb pdb:5LYB|rcsb pdb:5M1J|rcsb pdb:5MC6|rcsb pdb:5NDG|rcsb pdb:5NDW|rcsb pdb:5OBM|rcsb pdb:5TGA|rcsb pdb:5TGM|rcsb pdb:5U4P|refseq:NP_013268.1|sgd:S000004157|dip:DIP-6389N|mint:P05759	refseq:NP_001248319.1|refseq:NP_001248320.1|refseq:NP_001248322.1|refseq:NP_005822.1|ensembl:ENSG00000136436(gene)|ensembl:ENST00000258947(transcript)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016032"(viral process)|go:"GO:0016605"(PML body)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0098792"(xenophagy)|go:"GO:1901098"(positive regulation of autophagosome maturation)|interpro:IPR041611|interpro:IPR041641|mint:Q13137|rcsb pdb:2MXP|rcsb pdb:3VVV|rcsb pdb:3VVW|rcsb pdb:4GXL|rcsb pdb:4HAN|rcsb pdb:4XKL|rcsb pdb:5AAQ|rcsb pdb:5Z7A|rcsb pdb:5Z7L|refseq:NP_001248324.1|dip:DIP-57534N	-	-	crc64:609B121DA1A9DCB8	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:y4P4l0xJoM/1nElb1uDDTpc3oJA559292	rogid:N/GPJUGBK+Dh5Cg+csmafphuo9M9606	intact-crc:B6DCCB720E5EB048|rigid:uJnikN2n0oe5MdDeAivESK4TArY	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q13137	uniprotkb:P40325	intact:EBI-739580|uniprotkb:B4DDC4|uniprotkb:E7ENK0|uniprotkb:Q53FQ5|uniprotkb:Q53HB5|uniprotkb:Q6IBN9|uniprotkb:Q9BTF7|uniprotkb:B2RBT0|ensembl:ENSP00000258947|uniprotkb:B4E0C0|uniprotkb:E7ETP5|uniprotkb:B4DDT4|uniprotkb:B4DP36|uniprotkb:E9PBE5	intact:EBI-23614|uniprotkb:D6VV46|ensemblfungi:YGR268C	psi-mi:caco2_human(display_long)|uniprotkb:CALCOCO2(gene name)|psi-mi:CALCOCO2(display_short)|uniprotkb:NDP52(gene name synonym)|uniprotkb:Nuclear domain 10 protein NDP52(gene name synonym)|uniprotkb:Antigen nuclear dot 52 kDa protein(gene name synonym)|uniprotkb:Nuclear dot protein 52(gene name synonym)	psi-mi:hua1_yeast(display_long)|uniprotkb:HUA1(gene name)|psi-mi:HUA1(display_short)|uniprotkb:YGR268C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551316|imex:IM-24995-3400	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001248319.1|refseq:NP_001248320.1|refseq:NP_001248322.1|refseq:NP_005822.1|ensembl:ENSG00000136436(gene)|ensembl:ENST00000258947(transcript)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016032"(viral process)|go:"GO:0016605"(PML body)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0098792"(xenophagy)|go:"GO:1901098"(positive regulation of autophagosome maturation)|interpro:IPR041611|interpro:IPR041641|mint:Q13137|rcsb pdb:2MXP|rcsb pdb:3VVV|rcsb pdb:3VVW|rcsb pdb:4GXL|rcsb pdb:4HAN|rcsb pdb:4XKL|rcsb pdb:5AAQ|rcsb pdb:5Z7A|rcsb pdb:5Z7L|refseq:NP_001248324.1|dip:DIP-57534N	sgd:S000003500|refseq:NP_011784.3|dip:DIP-1987N|ensemblfungi:YGR268C(gene)|ensemblfungi:YGR268C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|interpro:IPR038910	-	crc64:609B121DA1A9DCB8	crc64:78029FD484168793	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:N/GPJUGBK+Dh5Cg+csmafphuo9M9606	rogid:xliNG9XUWbYRd0Nbu+xzCgxNrAs559292	intact-crc:2EA33CD566BDB369|rigid:ZU1zP1fdskcG37I7zNqOy95qCLQ	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q13137	uniprotkb:Q06630	intact:EBI-739580|uniprotkb:B4DDC4|uniprotkb:E7ENK0|uniprotkb:Q53FQ5|uniprotkb:Q53HB5|uniprotkb:Q6IBN9|uniprotkb:Q9BTF7|uniprotkb:B2RBT0|ensembl:ENSP00000258947|uniprotkb:B4E0C0|uniprotkb:E7ETP5|uniprotkb:B4DDT4|uniprotkb:B4DP36|uniprotkb:E9PBE5	intact:EBI-36794|uniprotkb:D6VSS5|ensemblfungi:YDR296W	psi-mi:caco2_human(display_long)|uniprotkb:CALCOCO2(gene name)|psi-mi:CALCOCO2(display_short)|uniprotkb:NDP52(gene name synonym)|uniprotkb:Nuclear domain 10 protein NDP52(gene name synonym)|uniprotkb:Antigen nuclear dot 52 kDa protein(gene name synonym)|uniprotkb:Nuclear dot protein 52(gene name synonym)	psi-mi:mhr1_yeast(display_long)|uniprotkb:MHR1(gene name)|psi-mi:MHR1(display_short)|uniprotkb:YDR296W(locus name)|uniprotkb:Cross-linked transcription component 1(gene name synonym)|uniprotkb:XTC1(gene name synonym)|uniprotkb:Mitochondrial large ribosomal subunit protein mL67(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551320|imex:IM-24995-3401	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001248319.1|refseq:NP_001248320.1|refseq:NP_001248322.1|refseq:NP_005822.1|ensembl:ENSG00000136436(gene)|ensembl:ENST00000258947(transcript)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016032"(viral process)|go:"GO:0016605"(PML body)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0098792"(xenophagy)|go:"GO:1901098"(positive regulation of autophagosome maturation)|interpro:IPR041611|interpro:IPR041641|mint:Q13137|rcsb pdb:2MXP|rcsb pdb:3VVV|rcsb pdb:3VVW|rcsb pdb:4GXL|rcsb pdb:4HAN|rcsb pdb:4XKL|rcsb pdb:5AAQ|rcsb pdb:5Z7A|rcsb pdb:5Z7L|refseq:NP_001248324.1|dip:DIP-57534N	sgd:S000002704|refseq:NP_010582.3|mint:Q06630|dip:DIP-5727N|ensemblfungi:YDR296W(gene)|ensemblfungi:YDR296W_mRNA(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0000150"(DNA strand exchange activity)|go:"GO:0003677"(DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0006310"(DNA recombination)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0032543"(mitochondrial translation)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0090297"(positive regulation of mitochondrial DNA replication)|interpro:IPR024629|rcsb pdb:3J6B|rcsb pdb:5MRC|rcsb pdb:5MRE|rcsb pdb:5MRF	-	crc64:609B121DA1A9DCB8	crc64:F26903A4814091C4	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:N/GPJUGBK+Dh5Cg+csmafphuo9M9606	rogid:eA38S7UNOpP716XSQ0zzhYm2TqA559292	intact-crc:833AE1E03CD777D3|rigid:Y9bWtIjFM+q05QneRyN40QS46AA	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q13137	uniprotkb:Q06707	intact:EBI-739580|uniprotkb:B4DDC4|uniprotkb:E7ENK0|uniprotkb:Q53FQ5|uniprotkb:Q53HB5|uniprotkb:Q6IBN9|uniprotkb:Q9BTF7|uniprotkb:B2RBT0|ensembl:ENSP00000258947|uniprotkb:B4E0C0|uniprotkb:E7ETP5|uniprotkb:B4DDT4|uniprotkb:B4DP36|uniprotkb:E9PBE5	intact:EBI-32671|uniprotkb:D6VZ20|ensemblfungi:YLR385C	psi-mi:caco2_human(display_long)|uniprotkb:CALCOCO2(gene name)|psi-mi:CALCOCO2(display_short)|uniprotkb:NDP52(gene name synonym)|uniprotkb:Nuclear domain 10 protein NDP52(gene name synonym)|uniprotkb:Antigen nuclear dot 52 kDa protein(gene name synonym)|uniprotkb:Nuclear dot protein 52(gene name synonym)	psi-mi:swc7_yeast(display_long)|uniprotkb:SWC7(gene name)|psi-mi:SWC7(display_short)|uniprotkb:AWS1(gene name synonym)|uniprotkb:YLR385C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551324|imex:IM-24995-3402	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001248319.1|refseq:NP_001248320.1|refseq:NP_001248322.1|refseq:NP_005822.1|ensembl:ENSG00000136436(gene)|ensembl:ENST00000258947(transcript)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016032"(viral process)|go:"GO:0016605"(PML body)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0098792"(xenophagy)|go:"GO:1901098"(positive regulation of autophagosome maturation)|interpro:IPR041611|interpro:IPR041641|mint:Q13137|rcsb pdb:2MXP|rcsb pdb:3VVV|rcsb pdb:3VVW|rcsb pdb:4GXL|rcsb pdb:4HAN|rcsb pdb:4XKL|rcsb pdb:5AAQ|rcsb pdb:5Z7A|rcsb pdb:5Z7L|refseq:NP_001248324.1|dip:DIP-57534N	refseq:NP_013489.1|sgd:S000004377|dip:DIP-4645N|mint:Q06707|ensemblfungi:YLR385C(gene)|ensemblfungi:YLR385C_mRNA(transcript)|go:"GO:0000812"(Swr1 complex)|go:"GO:0005634"(nucleus)|go:"GO:0006338"(chromatin remodeling)|interpro:IPR020195	-	crc64:609B121DA1A9DCB8	crc64:92CCE2FF3DCE72F1	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:N/GPJUGBK+Dh5Cg+csmafphuo9M9606	rogid:7DWWay9S3JHtIRpmJHyHeELBg5M559292	intact-crc:B960FB9E6541C54A|rigid:EY1ZjaIkZK52NNMpTnv/YZWpAdU	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P38340	uniprotkb:Q13155	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-745226|uniprotkb:Q75MR1|uniprotkb:Q96CZ5|uniprotkb:Q9P1L2|ensembl:ENSP00000223029|uniprotkb:F8W950	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:aimp2_human(display_long)|uniprotkb:Protein JTV-1(gene name synonym)|uniprotkb:AIMP2(gene name)|psi-mi:AIMP2(display_short)|uniprotkb:PRO0992(orf name)|uniprotkb:JTV1(gene name synonym)|uniprotkb:Multisynthase complex auxiliary component p38(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551356|imex:IM-24995-3410	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F	refseq:NP_006294.2|ensembl:ENSG00000106305(gene)|ensembl:ENST00000223029(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0006915"(apoptotic process)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0017101"(aminoacyl-tRNA synthetase multienzyme complex)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060510"(type II pneumocyte differentiation)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1903632"(positive regulation of aminoacyl-tRNA ligase activity)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR031889|interpro:IPR036282|interpro:IPR041503|interpro:IPR042360|mint:Q13155|rcsb pdb:4DPG|rcsb pdb:4YCU|rcsb pdb:4YCW|rcsb pdb:5A1N|rcsb pdb:5A34|rcsb pdb:5A5H|rcsb pdb:5Y6L|rcsb pdb:6ILD|rcsb pdb:6IY6|rcsb pdb:6JPV|rcsb pdb:6K39|reactome:R-HSA-2408522|reactome:R-HSA-379716|dip:DIP-34421N|refseq:NP_001313536.1	-	crc64:66699F37B0013088	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:VEBmJjo6t3dBY6mKpmUyVLamJFQ9606	intact-crc:168C3714BA86E424|rigid:jR+RbnhnSRFmhMPqtcFqWwRSkMw	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q13155	uniprotkb:P32502	intact:EBI-745226|uniprotkb:Q75MR1|uniprotkb:Q96CZ5|uniprotkb:Q9P1L2|ensembl:ENSP00000223029|uniprotkb:F8W950	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:aimp2_human(display_long)|uniprotkb:Protein JTV-1(gene name synonym)|uniprotkb:AIMP2(gene name)|psi-mi:AIMP2(display_short)|uniprotkb:PRO0992(orf name)|uniprotkb:JTV1(gene name synonym)|uniprotkb:Multisynthase complex auxiliary component p38(gene name synonym)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551348|imex:IM-24995-3408	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006294.2|ensembl:ENSG00000106305(gene)|ensembl:ENST00000223029(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0006915"(apoptotic process)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0017101"(aminoacyl-tRNA synthetase multienzyme complex)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060510"(type II pneumocyte differentiation)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1903632"(positive regulation of aminoacyl-tRNA ligase activity)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR031889|interpro:IPR036282|interpro:IPR041503|interpro:IPR042360|mint:Q13155|rcsb pdb:4DPG|rcsb pdb:4YCU|rcsb pdb:4YCW|rcsb pdb:5A1N|rcsb pdb:5A34|rcsb pdb:5A5H|rcsb pdb:5Y6L|rcsb pdb:6ILD|rcsb pdb:6IY6|rcsb pdb:6JPV|rcsb pdb:6K39|reactome:R-HSA-2408522|reactome:R-HSA-379716|dip:DIP-34421N|refseq:NP_001313536.1	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731	-	-	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:VEBmJjo6t3dBY6mKpmUyVLamJFQ9606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:552124131EBAFCE1|rigid:F3XDrjB1HkR0VvZZQGaFt+lZ3b0	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P0CH08	uniprotkb:Q13137	intact:EBI-11523108|uniprotkb:D6VVD9|uniprotkb:P04838|uniprotkb:P14796|uniprotkb:P61864|uniprotkb:Q6LA96|ensemblfungi:YIL148W|ensemblfungi:YKR094C	intact:EBI-739580|uniprotkb:B4DDC4|uniprotkb:E7ENK0|uniprotkb:Q53FQ5|uniprotkb:Q53HB5|uniprotkb:Q6IBN9|uniprotkb:Q9BTF7|uniprotkb:B2RBT0|ensembl:ENSP00000258947|uniprotkb:B4E0C0|uniprotkb:E7ETP5|uniprotkb:B4DDT4|uniprotkb:B4DP36|uniprotkb:E9PBE5	psi-mi:rl40a_yeast(display_long)|uniprotkb:RPL40A(gene name)|psi-mi:RPL40A(display_short)|uniprotkb:UBI1(gene name synonym)|uniprotkb:YIL148W(locus name)	psi-mi:caco2_human(display_long)|uniprotkb:CALCOCO2(gene name)|psi-mi:CALCOCO2(display_short)|uniprotkb:NDP52(gene name synonym)|uniprotkb:Nuclear domain 10 protein NDP52(gene name synonym)|uniprotkb:Antigen nuclear dot 52 kDa protein(gene name synonym)|uniprotkb:Nuclear dot protein 52(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551336|imex:IM-24995-3405	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:5NDG|rcsb pdb:5NDV|rcsb pdb:5NDW|rcsb pdb:5OBM|rcsb pdb:6WOO|interpro:IPR000626(Ubiquitin)|interpro:IPR001975(Ribosomal protein L40e)|interpro:IPR019954|interpro:IPR019956|interpro:IPR029071|rcsb pdb:3J6X|rcsb pdb:3J6Y|rcsb pdb:3J77|rcsb pdb:3J78|rcsb pdb:4U3M|rcsb pdb:4U3N|rcsb pdb:4U3U|rcsb pdb:4U4N|rcsb pdb:4U4O|rcsb pdb:4U4Q|rcsb pdb:4U4R|rcsb pdb:4U4U|rcsb pdb:4U4Y|rcsb pdb:4U4Z|rcsb pdb:4U50|rcsb pdb:4U51|rcsb pdb:4U52|rcsb pdb:4U53|rcsb pdb:4U55|rcsb pdb:4U56|rcsb pdb:4U6F|rcsb pdb:4V6I|rcsb pdb:4V88|rcsb pdb:4V8T|rcsb pdb:4V8Y|rcsb pdb:4V8Z|rcsb pdb:5APN|rcsb pdb:5APO|refseq:NP_012118.1|refseq:NP_013020.3|sgd:S000001410|rcsb pdb:6TB3|rcsb pdb:6TNU|rcsb pdb:5DGE|rcsb pdb:5M1J|rcsb pdb:5MC6|rcsb pdb:5TGM|rcsb pdb:6EF3|rcsb pdb:6OIG|rcsb pdb:6OA9|rcsb pdb:6OAA|rcsb pdb:6QIK|rcsb pdb:6QT0|rcsb pdb:6QTZ|rcsb pdb:6R84|rcsb pdb:6R87|rcsb pdb:6RI5|rcsb pdb:5FCI|rcsb pdb:5FCJ|rcsb pdb:5DGF|rcsb pdb:5DGV|rcsb pdb:5LYB|rcsb pdb:5TGA|rcsb pdb:6HHQ|rcsb pdb:5DC3|rcsb pdb:5I4L|rcsb pdb:6N8M|rcsb pdb:6N8N|rcsb pdb:6N8O|rcsb pdb:6I7O|rcsb pdb:7AZY|rcsb pdb:7B7D|rcsb pdb:7NRC|rcsb pdb:7NRD|reactome:R-SCE-1169408|reactome:R-SCE-5656169|rcsb pdb:5GAK|rcsb pdb:6Q8Y|ensemblfungi:YIL148W(gene)|ensemblfungi:YIL148W_mRNA(transcript)|ensemblfungi:YKR094C(gene)|ensemblfungi:YKR094C_mRNA(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0031386"(protein tag)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042254"(ribosome biogenesis)|rcsb pdb:6HD7|rcsb pdb:5ON6|rcsb pdb:5DAT|rcsb pdb:5JUO|rcsb pdb:5JUP|rcsb pdb:5JUS|rcsb pdb:5JUT|rcsb pdb:5JUU|rcsb pdb:5T62|rcsb pdb:5T6R|interpro:IPR038587|rcsb pdb:5MEI|rcsb pdb:5TBW|rcsb pdb:6GQ1|rcsb pdb:6GQB|rcsb pdb:6GQV|rcsb pdb:6R86|rcsb pdb:6S47|rcsb pdb:6NYO|rcsb pdb:6T4Q|rcsb pdb:6T7I|rcsb pdb:6T7T|rcsb pdb:6T83|rcsb pdb:6SNT|rcsb pdb:6SV4|rcsb pdb:6XIQ|rcsb pdb:6Z6J|rcsb pdb:6Z6K	refseq:NP_001248319.1|refseq:NP_001248320.1|refseq:NP_001248322.1|refseq:NP_005822.1|ensembl:ENSG00000136436(gene)|ensembl:ENST00000258947(transcript)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016032"(viral process)|go:"GO:0016605"(PML body)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0098792"(xenophagy)|go:"GO:1901098"(positive regulation of autophagosome maturation)|interpro:IPR041611|interpro:IPR041641|mint:Q13137|rcsb pdb:2MXP|rcsb pdb:3VVV|rcsb pdb:3VVW|rcsb pdb:4GXL|rcsb pdb:4HAN|rcsb pdb:4XKL|rcsb pdb:5AAQ|rcsb pdb:5Z7A|rcsb pdb:5Z7L|refseq:NP_001248324.1|dip:DIP-57534N	-	-	crc64:609B121DA1A9DCB8	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/03/16	rogid:6+5uVAktIpS9HyPHQ6BzXEuT/y0559292	rogid:N/GPJUGBK+Dh5Cg+csmafphuo9M9606	intact-crc:DB3E7DD23A03975B|rigid:5MdELz9eh+rq5yMhwoRRG8yaiP4	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q13137	uniprotkb:P40302	intact:EBI-739580|uniprotkb:B4DDC4|uniprotkb:E7ENK0|uniprotkb:Q53FQ5|uniprotkb:Q53HB5|uniprotkb:Q6IBN9|uniprotkb:Q9BTF7|uniprotkb:B2RBT0|ensembl:ENSP00000258947|uniprotkb:B4E0C0|uniprotkb:E7ETP5|uniprotkb:B4DDT4|uniprotkb:B4DP36|uniprotkb:E9PBE5	intact:EBI-13955|ensemblfungi:YMR314W|uniprotkb:D6W0E1	psi-mi:caco2_human(display_long)|uniprotkb:CALCOCO2(gene name)|psi-mi:CALCOCO2(display_short)|uniprotkb:NDP52(gene name synonym)|uniprotkb:Nuclear domain 10 protein NDP52(gene name synonym)|uniprotkb:Antigen nuclear dot 52 kDa protein(gene name synonym)|uniprotkb:Nuclear dot protein 52(gene name synonym)	psi-mi:psa6_yeast(display_long)|uniprotkb:PRE5(gene name)|psi-mi:PRE5(display_short)|uniprotkb:YMR314W(locus name)|uniprotkb:YM9924.06(orf name)|uniprotkb:Proteasome component PRE5(gene name synonym)|uniprotkb:Macropain subunit PRE5(gene name synonym)|uniprotkb:Proteinase YSCE subunit PRE5(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit PRE5(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551344|imex:IM-24995-3407	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001248319.1|refseq:NP_001248320.1|refseq:NP_001248322.1|refseq:NP_005822.1|ensembl:ENSG00000136436(gene)|ensembl:ENST00000258947(transcript)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016032"(viral process)|go:"GO:0016605"(PML body)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0098792"(xenophagy)|go:"GO:1901098"(positive regulation of autophagosome maturation)|interpro:IPR041611|interpro:IPR041641|mint:Q13137|rcsb pdb:2MXP|rcsb pdb:3VVV|rcsb pdb:3VVW|rcsb pdb:4GXL|rcsb pdb:4HAN|rcsb pdb:4XKL|rcsb pdb:5AAQ|rcsb pdb:5Z7A|rcsb pdb:5Z7L|refseq:NP_001248324.1|dip:DIP-57534N	rcsb pdb:4Y8T|rcsb pdb:4Y8U|rcsb pdb:4Y9Y|rcsb pdb:4Y9Z|rcsb pdb:4YA0|rcsb pdb:4YA1|rcsb pdb:4YA2|rcsb pdb:4YA3|rcsb pdb:4YA4|rcsb pdb:4YA5|rcsb pdb:4Y7X|rcsb pdb:4Y7Y|rcsb pdb:4Y80|rcsb pdb:4Y81|rcsb pdb:4Y82|rcsb pdb:4Y84|rcsb pdb:4Y8G|rcsb pdb:4Y8H|rcsb pdb:4Y8I|rcsb pdb:4Y8J|rcsb pdb:4Y8K|rcsb pdb:4Y8L|rcsb pdb:4Y8M|rcsb pdb:4Y8N|rcsb pdb:4Y8O|rcsb pdb:4Y8P|rcsb pdb:4Y8Q|rcsb pdb:4Y8R|rcsb pdb:4Y8S|rcsb pdb:5FG7|rcsb pdb:5FG9|rcsb pdb:5FGA|rcsb pdb:4YA7|rcsb pdb:4YA9|rcsb pdb:4Z1L|rcsb pdb:5A5B|rcsb pdb:5AHJ|rcsb pdb:5BOU|rcsb pdb:5BXL|rcsb pdb:5BXN|rcsb pdb:5CGF|rcsb pdb:5CGG|rcsb pdb:5CGH|rcsb pdb:5CGI|rcsb pdb:5CZ4|rcsb pdb:5CZ5|rcsb pdb:5CZ6|rcsb pdb:5CZ7|rcsb pdb:5CZ8|rcsb pdb:5CZ9|rcsb pdb:5CZA|rcsb pdb:5D0S|rcsb pdb:5D0T|rcsb pdb:5D0V|rcsb pdb:5D0W|rcsb pdb:5D0X|rcsb pdb:5D0Z|rcsb pdb:5DKI|rcsb pdb:5DKJ|rcsb pdb:5FGD|rcsb pdb:3HYE|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:3MG0|rcsb pdb:3MG4|rcsb pdb:3MG6|rcsb pdb:3MG7|rcsb pdb:3MG8|rcsb pdb:3NZJ|rcsb pdb:3NZW|rcsb pdb:3NZX|rcsb pdb:3OEU|rcsb pdb:3OEV|rcsb pdb:3OKJ|rcsb pdb:3SDI|rcsb pdb:3SDK|rcsb pdb:3SHJ|rcsb pdb:3TDD|rcsb pdb:3UN4|rcsb pdb:3UN8|rcsb pdb:3WXR|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:4EU2|rcsb pdb:4FZC|rcsb pdb:4FZG|rcsb pdb:4G4S|rcsb pdb:4GK7|rcsb pdb:4HNP|rcsb pdb:4HRC|rcsb pdb:4HRD|rcsb pdb:4INR|rcsb pdb:4INT|rcsb pdb:4INU|rcsb pdb:4J70|rcsb pdb:4JSQ|rcsb pdb:4JSU|rcsb pdb:4JT0|rcsb pdb:4LQI|rcsb pdb:4LTC|rcsb pdb:4NNN|rcsb pdb:4NNW|rcsb pdb:4NO1|rcsb pdb:4NO6|rcsb pdb:4NO8|rcsb pdb:4NO9|rcsb pdb:5FGE|rcsb pdb:5FGF|rcsb pdb:5FGG|rcsb pdb:5FGH|rcsb pdb:5FGI|rcsb pdb:5FHS|rcsb pdb:5JHR|rcsb pdb:5JHS|rcsb pdb:5L52|rcsb pdb:5L54|rcsb pdb:5L55|rcsb pdb:5L5A|rcsb pdb:5L5B|rcsb pdb:5L5D|rcsb pdb:5L5E|rcsb pdb:5L5F|rcsb pdb:5L5H|rcsb pdb:5L5I|rcsb pdb:5L5J|rcsb pdb:5L5O|rcsb pdb:5L5P|rcsb pdb:5L5Q|rcsb pdb:5L5R|rcsb pdb:4Q1S|rcsb pdb:4QBY|rcsb pdb:4QLQ|rcsb pdb:4QLS|rcsb pdb:4QLT|rcsb pdb:4QLU|rcsb pdb:4QLV|rcsb pdb:4QUX|rcsb pdb:4QUY|rcsb pdb:4QV0|rcsb pdb:4QV1|rcsb pdb:4QV3|rcsb pdb:4QV4|rcsb pdb:4QV5|rcsb pdb:4QV6|rcsb pdb:4QV7|rcsb pdb:4QV8|rcsb pdb:4QV9|rcsb pdb:4QVL|ensemblfungi:YMR314W(gene)|ensemblfungi:YMR314W_mRNA(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0042175"(nuclear outer membrane-endoplasmic reticulum membrane network)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR035144|rcsb pdb:1FNT|rcsb pdb:1G0U|rcsb pdb:1G65|rcsb pdb:1JD2|rcsb pdb:1RYP|rcsb pdb:1Z7Q|rcsb pdb:2F16|rcsb pdb:2FAK|rcsb pdb:2GPL|rcsb pdb:2ZCY|rcsb pdb:3BDM|rcsb pdb:3D29|rcsb pdb:3DY3|rcsb pdb:3DY4|rcsb pdb:3E47|rcsb pdb:3GPJ|rcsb pdb:3GPT|rcsb pdb:3GPW|rcsb pdb:4QVM|rcsb pdb:4QVN|rcsb pdb:4QVP|rcsb pdb:4QVQ|rcsb pdb:4QVV|rcsb pdb:4QVW|rcsb pdb:4QVY|rcsb pdb:4QW0|rcsb pdb:4QW1|rcsb pdb:4QW3|rcsb pdb:4QW4|rcsb pdb:4QW5|rcsb pdb:4QW6|rcsb pdb:4QW7|rcsb pdb:4QWF|rcsb pdb:4QWG|rcsb pdb:4QWI|rcsb pdb:4QWJ|rcsb pdb:4QWK|rcsb pdb:4QWL|rcsb pdb:4QWR|rcsb pdb:4QWS|rcsb pdb:4QWU|rcsb pdb:4QWX|rcsb pdb:4QXJ|rcsb pdb:4QZ0|rcsb pdb:4QZ1|rcsb pdb:4QZ2|rcsb pdb:4QZ3|rcsb pdb:4QZ4|rcsb pdb:4QZ5|rcsb pdb:4QZ6|rcsb pdb:4QZ7|rcsb pdb:4QZW|rcsb pdb:4QZX|rcsb pdb:4QZZ|rcsb pdb:4R00|rcsb pdb:4R02|rcsb pdb:4R17|rcsb pdb:4R18|rcsb pdb:4RUR|rcsb pdb:4V7O|rcsb pdb:4X6Z|rcsb pdb:4Y69|rcsb pdb:4Y6A|rcsb pdb:4Y6V|rcsb pdb:4Y6Z|rcsb pdb:4Y70|rcsb pdb:4Y74|rcsb pdb:4Y75|rcsb pdb:4Y77|rcsb pdb:4Y78|rcsb pdb:4Y7W|rcsb pdb:5LTT|rcsb pdb:5M2B|rcsb pdb:5MP9|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5NIF|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6G7F|rcsb pdb:6G8M|rcsb pdb:6G8N|rcsb pdb:6GOP|rcsb pdb:6H39|rcsb pdb:6HTB|rcsb pdb:6HTC|rcsb pdb:6HTD|rcsb pdb:6HTP|rcsb pdb:6HTR|rcsb pdb:6HUB|rcsb pdb:6HUC|rcsb pdb:6HUQ|rcsb pdb:6HUU|rcsb pdb:6HUV|rcsb pdb:6HV3|rcsb pdb:6HV4|rcsb pdb:6HV5|rcsb pdb:6HV7|rcsb pdb:6HVA|rcsb pdb:6HVR|rcsb pdb:6HVS|rcsb pdb:6HVT|rcsb pdb:6HVU|rcsb pdb:6HVV|rcsb pdb:5L5S|rcsb pdb:5L5T|rcsb pdb:5L5U|rcsb pdb:5L5V|rcsb pdb:5L5W|rcsb pdb:5L5X|rcsb pdb:5L5Y|rcsb pdb:5L5Z|rcsb pdb:5L60|rcsb pdb:5L61|rcsb pdb:5L62|rcsb pdb:5L63|rcsb pdb:5L64|rcsb pdb:5L65|rcsb pdb:5L66|rcsb pdb:5L67|rcsb pdb:5L68|rcsb pdb:5L69|rcsb pdb:5L6A|rcsb pdb:5L6B|rcsb pdb:5L6C|rcsb pdb:5LAI|rcsb pdb:5LAJ|rcsb pdb:6HVW|rcsb pdb:6HVX|rcsb pdb:6HVY|rcsb pdb:6HW0|rcsb pdb:6HW3|rcsb pdb:6HW4|rcsb pdb:6HW5|rcsb pdb:6HW6|rcsb pdb:6HW7|rcsb pdb:6HW8|rcsb pdb:6HW9|rcsb pdb:6HWA|rcsb pdb:6HWB|rcsb pdb:6HWC|rcsb pdb:6HWD|rcsb pdb:6HWE|rcsb pdb:6HWF|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2X|rcsb pdb:6J30|rcsb pdb:6ZOU|rcsb pdb:6ZP6|rcsb pdb:6ZP8|rcsb pdb:7LS5|rcsb pdb:7LS6|rcsb pdb:7LSX|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|rcsb pdb:6J2Q|refseq:NP_014045.1|sgd:S000004931|mint:P40302|dip:DIP-1528N	-	crc64:609B121DA1A9DCB8	crc64:C43CBCC1C6B9E39E	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:N/GPJUGBK+Dh5Cg+csmafphuo9M9606	rogid:C9GPb0JAklkBz0t/YYqRMNEiQss559292	intact-crc:CC9334F7B11661B3|rigid:ZfDt5eZYjTzVB9Ttb5Mz5Rmtrd4	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P38815	uniprotkb:Q13137	intact:EBI-24665|uniprotkb:D3DL55|ensemblfungi:YHR105W	intact:EBI-739580|uniprotkb:B4DDC4|uniprotkb:E7ENK0|uniprotkb:Q53FQ5|uniprotkb:Q53HB5|uniprotkb:Q6IBN9|uniprotkb:Q9BTF7|uniprotkb:B2RBT0|ensembl:ENSP00000258947|uniprotkb:B4E0C0|uniprotkb:E7ETP5|uniprotkb:B4DDT4|uniprotkb:B4DP36|uniprotkb:E9PBE5	psi-mi:ypt35_yeast(display_long)|uniprotkb:YHR105W(locus name)|uniprotkb:YPT35(gene name)|psi-mi:YPT35(display_short)	psi-mi:caco2_human(display_long)|uniprotkb:CALCOCO2(gene name)|psi-mi:CALCOCO2(display_short)|uniprotkb:NDP52(gene name synonym)|uniprotkb:Nuclear domain 10 protein NDP52(gene name synonym)|uniprotkb:Antigen nuclear dot 52 kDa protein(gene name synonym)|uniprotkb:Nuclear dot protein 52(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551340|imex:IM-24995-3406	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011973.1|sgd:S000001147|dip:DIP-1881N|ensemblfungi:YHR105W(gene)|ensemblfungi:YHR105W_mRNA(transcript)|go:"GO:0005768"(endosome)|go:"GO:0010008"(endosome membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|interpro:IPR001683(Phox-like)|interpro:IPR036871|interpro:IPR037917	refseq:NP_001248319.1|refseq:NP_001248320.1|refseq:NP_001248322.1|refseq:NP_005822.1|ensembl:ENSG00000136436(gene)|ensembl:ENST00000258947(transcript)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016032"(viral process)|go:"GO:0016605"(PML body)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0098792"(xenophagy)|go:"GO:1901098"(positive regulation of autophagosome maturation)|interpro:IPR041611|interpro:IPR041641|mint:Q13137|rcsb pdb:2MXP|rcsb pdb:3VVV|rcsb pdb:3VVW|rcsb pdb:4GXL|rcsb pdb:4HAN|rcsb pdb:4XKL|rcsb pdb:5AAQ|rcsb pdb:5Z7A|rcsb pdb:5Z7L|refseq:NP_001248324.1|dip:DIP-57534N	-	crc64:2ADD21AF107094DC	crc64:609B121DA1A9DCB8	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:fUTJG8BaTveH3zB/0W1vNh4BU2Y559292	rogid:N/GPJUGBK+Dh5Cg+csmafphuo9M9606	intact-crc:CB2A2A2C4BB8ECC4|rigid:uCIg90GaLpsIGsMeB/4WqatfkPQ	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P53930	uniprotkb:Q13155	intact:EBI-28841|uniprotkb:Q6B1N1|uniprotkb:D6W173|ensemblfungi:YNL107W	intact:EBI-745226|uniprotkb:Q75MR1|uniprotkb:Q96CZ5|uniprotkb:Q9P1L2|ensembl:ENSP00000223029|uniprotkb:F8W950	psi-mi:af9_yeast(display_long)|uniprotkb:N1966(orf name)|uniprotkb:YNL107W(locus name)|uniprotkb:YAF9(gene name)|psi-mi:YAF9(display_short)	psi-mi:aimp2_human(display_long)|uniprotkb:Protein JTV-1(gene name synonym)|uniprotkb:AIMP2(gene name)|psi-mi:AIMP2(display_short)|uniprotkb:PRO0992(orf name)|uniprotkb:JTV1(gene name synonym)|uniprotkb:Multisynthase complex auxiliary component p38(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551352|imex:IM-24995-3409	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005051|refseq:NP_014292.3|dip:DIP-4347N|mint:P53930|ensemblfungi:YNL107W(gene)|ensemblfungi:YNL107W_mRNA(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000812"(Swr1 complex)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006348"|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0043486"(histone exchange)|interpro:IPR005033(YEATS)|interpro:IPR037989|interpro:IPR038704|rcsb pdb:3FK3|rcsb pdb:3RLS|rcsb pdb:6AXJ|reactome:R-SCE-674695|reactome:R-SCE-75955	refseq:NP_006294.2|ensembl:ENSG00000106305(gene)|ensembl:ENST00000223029(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0006915"(apoptotic process)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0017101"(aminoacyl-tRNA synthetase multienzyme complex)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060510"(type II pneumocyte differentiation)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1903632"(positive regulation of aminoacyl-tRNA ligase activity)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR031889|interpro:IPR036282|interpro:IPR041503|interpro:IPR042360|mint:Q13155|rcsb pdb:4DPG|rcsb pdb:4YCU|rcsb pdb:4YCW|rcsb pdb:5A1N|rcsb pdb:5A34|rcsb pdb:5A5H|rcsb pdb:5Y6L|rcsb pdb:6ILD|rcsb pdb:6IY6|rcsb pdb:6JPV|rcsb pdb:6K39|reactome:R-HSA-2408522|reactome:R-HSA-379716|dip:DIP-34421N|refseq:NP_001313536.1	-	crc64:1FE08F72942061D1	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:oIwHCTPMu/kBEXUm82Yw5C0YYXw559292	rogid:VEBmJjo6t3dBY6mKpmUyVLamJFQ9606	intact-crc:6981D02443E5B63D|rigid:WBnb8LWe6+acKCVJpW2TGVkKTlg	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P38932	uniprotkb:Q13190	intact:EBI-20444|uniprotkb:D6VU50|ensemblfungi:YGL095C	intact:EBI-714206|uniprotkb:Q5U0D4|uniprotkb:Q7Z3T6|uniprotkb:Q9BUG1|uniprotkb:B2R8T2|ensembl:ENSP00000294179|uniprotkb:F8W8Q9	psi-mi:vps45_yeast(display_long)|uniprotkb:VPS45(gene name)|psi-mi:VPS45(display_short)|uniprotkb:STT10(gene name synonym)|uniprotkb:VPL28(gene name synonym)|uniprotkb:YGL095C(locus name)	psi-mi:stx5_human(display_long)|uniprotkb:STX5(gene name)|psi-mi:STX5(display_short)|uniprotkb:STX5A(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551372|imex:IM-24995-3414	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003063|refseq:NP_011420.3|ensemblfungi:YGL095C(gene)|ensemblfungi:YGL095C_mRNA(transcript)|go:"GO:0000011"(vacuole inheritance)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0007033"(vacuole organization)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0035543"(positive regulation of SNARE complex assembly)|go:"GO:0048210"(Golgi vesicle fusion to target membrane)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR001619(Sec1-like protein)|interpro:IPR027482|interpro:IPR036045|interpro:IPR043127|interpro:IPR043154|reactome:R-SCE-983231|dip:DIP-2693N|mint:P38932	refseq:NP_003155.2|ensembl:ENSG00000162236(gene)|ensembl:ENST00000294179(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006906"(vesicle fusion)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0031982"(vesicle)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034498"(early endosome to Golgi transport)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0045296"(cadherin binding)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048278"(vesicle docking)|go:"GO:0048280"(vesicle fusion with Golgi apparatus)|go:"GO:0090166"(Golgi disassembly)|go:"GO:1903358"(regulation of Golgi organization)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|interpro:IPR021538|mint:Q13190|rcsb pdb:3EFO|reactome:R-HSA-204005|reactome:R-HSA-5694530|reactome:R-HSA-6807878|reactome:R-HSA-6811438|reactome:R-HSA-8980692|reactome:R-HSA-9013106|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|reactome:R-HSA-9013408|reactome:R-HSA-9609523|refseq:NP_001231595.1|refseq:NP_001317223.1|dip:DIP-56987N	-	crc64:4AA50D568228228F	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:HSNdSBz2AD5AS/nSUjPV02ym8HQ559292	rogid:cR4cS695ZWQQ5Bkim9HqmCE0hCE9606	intact-crc:1CD51F289896830C|rigid:fn3RpZMtWU2aSdpMHGtsEOjS0pI	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q12055	uniprotkb:Q13164	intact:EBI-22197|uniprotkb:D6VRI5|uniprotkb:E9P8W4|ensemblfungi:YDL166C	intact:EBI-1213983|uniprotkb:Q16634|uniprotkb:Q59F50|uniprotkb:Q6QLU7|uniprotkb:Q7L4P4|uniprotkb:Q969G1|uniprotkb:Q96G51|intact:EBI-28979986|ensembl:ENSP00000311005|ensembl:ENSP00000378966|ensembl:ENSP00000378968	psi-mi:kad6_yeast(display_long)|uniprotkb:FAP7(gene name)|psi-mi:FAP7(display_short)|uniprotkb:POS9-activating factor 7(gene name synonym)|uniprotkb:YDL166C(locus name)|uniprotkb:Dual activity adenylate kinase/ATPase(gene name synonym)	psi-mi:mk07_human(display_long)|uniprotkb:MAPK7(gene name)|psi-mi:MAPK7(display_short)|uniprotkb:BMK1(gene name synonym)|uniprotkb:ERK5(gene name synonym)|uniprotkb:PRKM7(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 5(gene name synonym)|uniprotkb:Big MAP kinase 1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551360|imex:IM-24995-3411	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010115.1|sgd:S000002325|reactome:R-SCE-499943|dip:DIP-4793N|ensemblfungi:YDL166C(gene)|ensemblfungi:YDL166C_mRNA(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0004017"(adenylate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0034599"(cellular response to oxidative stress)|interpro:IPR020618|interpro:IPR027417	refseq:NP_002740.2|refseq:NP_620601.1|refseq:NP_620602.2|refseq:NP_620603.2|ensembl:ENST00000299612|ensembl:ENSP00000299612|ensembl:ENSP00000311005|ensembl:ENSP00000378966|ensembl:ENSP00000378968|refseq:XP_011522259.1|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0036003"(positive regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0051019"(mitogen-activated protein kinase binding)|go:"GO:0051247"(positive regulation of protein metabolic process)|go:"GO:0051344"(negative regulation of cyclic-nucleotide phosphodiesterase activity)|go:"GO:0060761"(negative regulation of response to cytokine stimulus)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071499"(cellular response to laminar fluid shear stress)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1902176"(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:2000352"(negative regulation of endothelial cell apoptotic process)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q13164|rcsb pdb:2Q8Y|rcsb pdb:4B99|rcsb pdb:4IC7|rcsb pdb:4IC8|rcsb pdb:4ZSG|rcsb pdb:4ZSJ|rcsb pdb:4ZSL|rcsb pdb:5BYY|rcsb pdb:5BYZ|rcsb pdb:5O7I|rcsb pdb:6HKM|rcsb pdb:6HKN|reactome:R-HSA-198753|reactome:R-HSA-198765|reactome:R-HSA-202670|reactome:R-HSA-2559582|reactome:R-HSA-881907|reactome:R-HSA-8853659|ensembl:ENSG00000166484(gene)|ensembl:ENST00000308406(transcript)|ensembl:ENST00000395602(transcript)|ensembl:ENST00000395604(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0016605"(PML body)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0030154"(cell differentiation)|go:"GO:0034115"(negative regulation of heterotypic cell-cell adhesion)	-	crc64:836A25B0D7E2633C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:/hVE29n+kxI3CjMUlxtJxrvUpYk559292	rogid:dUTMnlgdjEkFhq0i6RmvpX5U7BM9606	intact-crc:5044D89E0B60A09D|rigid:5P8RW0Uuz0dwmHid/nbNPuLrHSQ	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q13164	uniprotkb:P53286	intact:EBI-1213983|uniprotkb:Q16634|uniprotkb:Q59F50|uniprotkb:Q6QLU7|uniprotkb:Q7L4P4|uniprotkb:Q969G1|uniprotkb:Q96G51|intact:EBI-28979986|ensembl:ENSP00000311005|ensembl:ENSP00000378966|ensembl:ENSP00000378968	intact:EBI-3796|uniprotkb:D6VUS2|ensemblfungi:YGR142W	psi-mi:mk07_human(display_long)|uniprotkb:MAPK7(gene name)|psi-mi:MAPK7(display_short)|uniprotkb:BMK1(gene name synonym)|uniprotkb:ERK5(gene name synonym)|uniprotkb:PRKM7(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 5(gene name synonym)|uniprotkb:Big MAP kinase 1(gene name synonym)	psi-mi:btn2_yeast(display_long)|uniprotkb:YGR142W(locus name)|uniprotkb:BTN2(gene name)|psi-mi:BTN2(display_short)|uniprotkb:Batten disease protein 2(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551364|imex:IM-24995-3412	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002740.2|refseq:NP_620601.1|refseq:NP_620602.2|refseq:NP_620603.2|ensembl:ENST00000299612|ensembl:ENSP00000299612|ensembl:ENSP00000311005|ensembl:ENSP00000378966|ensembl:ENSP00000378968|refseq:XP_011522259.1|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0036003"(positive regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0051019"(mitogen-activated protein kinase binding)|go:"GO:0051247"(positive regulation of protein metabolic process)|go:"GO:0051344"(negative regulation of cyclic-nucleotide phosphodiesterase activity)|go:"GO:0060761"(negative regulation of response to cytokine stimulus)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071499"(cellular response to laminar fluid shear stress)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1902176"(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:2000352"(negative regulation of endothelial cell apoptotic process)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q13164|rcsb pdb:2Q8Y|rcsb pdb:4B99|rcsb pdb:4IC7|rcsb pdb:4IC8|rcsb pdb:4ZSG|rcsb pdb:4ZSJ|rcsb pdb:4ZSL|rcsb pdb:5BYY|rcsb pdb:5BYZ|rcsb pdb:5O7I|rcsb pdb:6HKM|rcsb pdb:6HKN|reactome:R-HSA-198753|reactome:R-HSA-198765|reactome:R-HSA-202670|reactome:R-HSA-2559582|reactome:R-HSA-881907|reactome:R-HSA-8853659|ensembl:ENSG00000166484(gene)|ensembl:ENST00000308406(transcript)|ensembl:ENST00000395602(transcript)|ensembl:ENST00000395604(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0016605"(PML body)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0030154"(cell differentiation)|go:"GO:0034115"(negative regulation of heterotypic cell-cell adhesion)	sgd:S000003374|refseq:NP_011658.3|dip:DIP-5534N|mint:P53286|ensemblfungi:YGR142W(gene)|ensemblfungi:YGR142W_mRNA(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005634"(nucleus)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006865"(amino acid transport)|go:"GO:0006885"(regulation of pH)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051087"(chaperone binding)|go:"GO:0140311"(protein sequestering activity)	-	-	crc64:E7AE1EB1E3612F3E	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:dUTMnlgdjEkFhq0i6RmvpX5U7BM9606	rogid:Cu27xkwGMNyS4zLvUaG1UeH2mE0559292	intact-crc:B3A22859775631E2|rigid:JEZNN4b3KaX3CQ1ZRZjBKbJOam0	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q12156	uniprotkb:Q13164	intact:EBI-30371|uniprotkb:D6VS49|ensemblfungi:YDR063W	intact:EBI-1213983|uniprotkb:Q16634|uniprotkb:Q59F50|uniprotkb:Q6QLU7|uniprotkb:Q7L4P4|uniprotkb:Q969G1|uniprotkb:Q96G51|intact:EBI-28979986|ensembl:ENSP00000311005|ensembl:ENSP00000378966|ensembl:ENSP00000378968	psi-mi:aim7_yeast(display_long)|uniprotkb:AIM7(gene name)|psi-mi:AIM7(display_short)|uniprotkb:D4245(orf name)|uniprotkb:YDR063W(locus name)|uniprotkb:Altered inheritance rate of mitochondria protein 7(gene name synonym)	psi-mi:mk07_human(display_long)|uniprotkb:MAPK7(gene name)|psi-mi:MAPK7(display_short)|uniprotkb:BMK1(gene name synonym)|uniprotkb:ERK5(gene name synonym)|uniprotkb:PRKM7(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 5(gene name synonym)|uniprotkb:Big MAP kinase 1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551368|imex:IM-24995-3413	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010348.1|sgd:S000002470|dip:DIP-1818N|mint:Q12156|ensemblfungi:YDR063W(gene)|ensemblfungi:YDR063W_mRNA(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0030479"(actin cortical patch)|go:"GO:0034316"(negative regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0071846"(actin filament debranching)|go:"GO:0071933"(Arp2/3 complex binding)|interpro:IPR002108(Actin-binding, cofilin/tropomyosin type)|interpro:IPR011171(Glia maturation factor beta)|interpro:IPR029006|reactome:R-SCE-6798695	refseq:NP_002740.2|refseq:NP_620601.1|refseq:NP_620602.2|refseq:NP_620603.2|ensembl:ENST00000299612|ensembl:ENSP00000299612|ensembl:ENSP00000311005|ensembl:ENSP00000378966|ensembl:ENSP00000378968|refseq:XP_011522259.1|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0036003"(positive regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0051019"(mitogen-activated protein kinase binding)|go:"GO:0051247"(positive regulation of protein metabolic process)|go:"GO:0051344"(negative regulation of cyclic-nucleotide phosphodiesterase activity)|go:"GO:0060761"(negative regulation of response to cytokine stimulus)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071499"(cellular response to laminar fluid shear stress)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1902176"(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:2000352"(negative regulation of endothelial cell apoptotic process)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q13164|rcsb pdb:2Q8Y|rcsb pdb:4B99|rcsb pdb:4IC7|rcsb pdb:4IC8|rcsb pdb:4ZSG|rcsb pdb:4ZSJ|rcsb pdb:4ZSL|rcsb pdb:5BYY|rcsb pdb:5BYZ|rcsb pdb:5O7I|rcsb pdb:6HKM|rcsb pdb:6HKN|reactome:R-HSA-198753|reactome:R-HSA-198765|reactome:R-HSA-202670|reactome:R-HSA-2559582|reactome:R-HSA-881907|reactome:R-HSA-8853659|ensembl:ENSG00000166484(gene)|ensembl:ENST00000308406(transcript)|ensembl:ENST00000395602(transcript)|ensembl:ENST00000395604(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0016605"(PML body)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0030154"(cell differentiation)|go:"GO:0034115"(negative regulation of heterotypic cell-cell adhesion)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:gNpFPaIObSMCgvbNabMJOjJMjco559292	rogid:dUTMnlgdjEkFhq0i6RmvpX5U7BM9606	intact-crc:8D7C604EA684545C|rigid:u53oTcdp6xI5CMxJ6KZDXnSo5HE	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q13422-7	uniprotkb:P28004	intact:EBI-11522367|ensembl:ENSP00000352123|ensembl:ENSP00000413025	intact:EBI-20640|uniprotkb:D6VPI6|ensemblfungi:YAL032C	psi-mi:q13422-7(display_long)|uniprotkb:IKZF1(gene name)|psi-mi:IKZF1(display_short)|uniprotkb:IK1(gene name synonym)|uniprotkb:IKAROS(gene name synonym)|uniprotkb:Ikaros family zinc finger protein 1(gene name synonym)|uniprotkb:LYF1(gene name synonym)|uniprotkb:Lymphoid transcription factor LyF-1(gene name synonym)|uniprotkb:ZNFN1A1(gene name synonym)	psi-mi:prp45_yeast(display_long)|uniprotkb:YAL032C(locus name)|uniprotkb:PRP45(gene name)|psi-mi:PRP45(display_short)|uniprotkb:FUN20(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551392|imex:IM-24995-3419	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-745305(isoform-parent)|ensembl:ENSG00000185811(gene)|ensembl:ENST00000359197(transcript)|ensembl:ENST00000439701(transcript)|uniprotkb:Q13422-7(isoform-parent)	refseq:NP_009370.1|sgd:S000000030|ensemblfungi:YAL032C(gene)|ensemblfungi:YAL032C_mRNA(transcript)|go:"GO:0000350"(generation of catalytic spliceosome for second transesterification step)|go:"GO:0005634"(nucleus)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|interpro:IPR004015(SKIP/SNW)|interpro:IPR017862|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|dip:DIP-2774N|mint:P28004	-	-	crc64:FE5A724186D7FE84	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:ou/ovXYoMneBNVp4pj38VxenfyY9606	rogid:qoHF1UsO3k+JOTOfigSuy2P84/k559292	intact-crc:827379A8E4622760|rigid:WMydF67ZCWFq4i6PYP0NLZP8YGw	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q06671	uniprotkb:Q13422-7	intact:EBI-3685534|uniprotkb:D6VZ66|ensemblfungi:YLR431C	intact:EBI-11522367|ensembl:ENSP00000352123|ensembl:ENSP00000413025	psi-mi:atg23_yeast(display_long)|uniprotkb:ATG23(gene name)|psi-mi:ATG23(display_short)|uniprotkb:CVT23(gene name synonym)|uniprotkb:Cytoplasm to vacuole targeting protein 23(gene name synonym)|uniprotkb:YLR431C(locus name)	psi-mi:q13422-7(display_long)|uniprotkb:IKZF1(gene name)|psi-mi:IKZF1(display_short)|uniprotkb:IK1(gene name synonym)|uniprotkb:IKAROS(gene name synonym)|uniprotkb:Ikaros family zinc finger protein 1(gene name synonym)|uniprotkb:LYF1(gene name synonym)|uniprotkb:Lymphoid transcription factor LyF-1(gene name synonym)|uniprotkb:ZNFN1A1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551388|imex:IM-24995-3418	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000004423|refseq:NP_013535.1|ensemblfungi:YLR431C(gene)|ensemblfungi:YLR431C_mRNA(transcript)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0044805"(late nucleophagy)	intact:EBI-745305(isoform-parent)|ensembl:ENSG00000185811(gene)|ensembl:ENST00000359197(transcript)|ensembl:ENST00000439701(transcript)|uniprotkb:Q13422-7(isoform-parent)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:6KEtQbyIfmG3hnxsqr3+hHGrEa0559292	rogid:ou/ovXYoMneBNVp4pj38VxenfyY9606	intact-crc:E31EB5E6350F935A|rigid:g+xJ5gDXbhYnOsvVB5FAHzXHfAk	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q13191	intact:EBI-11522220	intact:EBI-744027|uniprotkb:Q63Z43|uniprotkb:A8K9S7|uniprotkb:Q13192|uniprotkb:Q13193|uniprotkb:Q3LIC0|uniprotkb:Q8IVC5|uniprotkb:B7WNM4|intact:EBI-28969458|ensembl:ENSP00000377598|intact:EBI-8051403|intact:MINT-7907019	-	psi-mi:cblb_human(display_long)|uniprotkb:Signal transduction protein CBL-B(gene name synonym)|uniprotkb:SH3-binding protein CBL-B(gene name synonym)|uniprotkb:Casitas B-lineage lymphoma proto-oncogene b(gene name synonym)|uniprotkb:RING finger protein 56(gene name synonym)|uniprotkb:CBLB(gene name)|psi-mi:CBLB(display_short)|uniprotkb:RNF56(gene name synonym)|uniprotkb:Nbla00127(orf name)|uniprotkb:RING-type E3 ubiquitin transferase CBL-B(gene name synonym)	psi-mi:lsb3(display_short)|psi-mi:EBI-11522220(display_long)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551376|imex:IM-24995-3415	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_733762.2|refseq:NP_001308717.1|ensembl:ENSP00000377598|ensembl:ENST00000403724|ensembl:ENSP00000384816|ensembl:ENST00000405772|ensembl:ENSP00000384938|refseq:XP_011511559.1|ensembl:ENSG00000114423(gene)|ensembl:ENST00000394030(transcript)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0002669"(positive regulation of T cell anergy)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0007175"(negative regulation of epidermal growth factor-activated receptor activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0018193"(peptidyl-amino acid modification)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0005829"(cytosol)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042110"(T cell activation)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046642"(negative regulation of alpha-beta T cell proliferation)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050860"(negative regulation of T cell receptor signaling pathway)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:2000583"(regulation of platelet-derived growth factor receptor-alpha signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003153(Adaptor protein Cbl, N-terminal helical)|interpro:IPR011992(EF-Hand type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014742(Adaptor protein Cbl, SH2-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR017907|interpro:IPR024159|interpro:IPR024162|interpro:IPR036537|interpro:IPR036860|interpro:IPR039520|mint:Q13191|rcsb pdb:2AK5|rcsb pdb:2BZ8|rcsb pdb:2DO6|rcsb pdb:2J6F|rcsb pdb:2JNH|rcsb pdb:2LDR|rcsb pdb:2OOA|rcsb pdb:2OOB|rcsb pdb:3PFV|rcsb pdb:3VGO|rcsb pdb:3ZNI|reactome:R-HSA-983168|interpro:IPR014741(Adaptor protein Cbl, EF hand-like)|dip:DIP-33091N	-	-	-	no-uniprot-update:	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:cJ5eLH0TMyM6OtmS1sM3rhsrsIk9606	rogid:lsGJZWImagMoiiCZztCcxCn2LlU4932	intact-crc:C6D70101A46FDC4E|rigid:b4mXxgUlwqy89aav6wvlaaGSutc	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q13287	uniprotkb:P39078	intact:EBI-372942|uniprotkb:Q53TI8|intact:EBI-10174268|uniprotkb:Q8WTW2|uniprotkb:Q9BVE5|uniprotkb:B5BU69|ensembl:ENSP00000243346	intact:EBI-19054|uniprotkb:Q07561|uniprotkb:D6VRK5|ensemblfungi:YDL143W	psi-mi:nmi_human(display_long)|uniprotkb:NMI(gene name)|psi-mi:NMI(display_short)|uniprotkb:N-myc and STAT interactor(gene name synonym)	psi-mi:tcpd_yeast(display_long)|uniprotkb:YDL143W(locus name)|uniprotkb:CCT4(gene name)|psi-mi:CCT4(display_short)|uniprotkb:ANC2(gene name synonym)|uniprotkb:TCP4(gene name synonym)|uniprotkb:CCT-delta(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551380|imex:IM-24995-3416	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004679.2|refseq:XP_005246998.1|ensembl:ENSG00000123609(gene)|ensembl:ENST00000243346(transcript)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0032687"(negative regulation of interferon-alpha production)|go:"GO:0032688"(negative regulation of interferon-beta production)|go:"GO:0034142"(toll-like receptor 4 signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0045824"(negative regulation of innate immune response)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:1901223"(negative regulation of NIK/NF-kappaB signaling)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1902524"(positive regulation of protein K48-linked ubiquitination)|interpro:IPR009909(Nmi/IFP 35)|interpro:IPR009938(Interferon-induced 35 kDa, N-terminal)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033527|mint:Q13287|refseq:XP_016860736.1	refseq:NP_010138.1|sgd:S000002302|ensemblfungi:YDL143W(gene)|ensemblfungi:YDL143W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0006457"(protein folding)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012717(T-complex protein 1, delta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|rcsb pdb:4V81|rcsb pdb:4V8R|rcsb pdb:4V94|rcsb pdb:5GW4|rcsb pdb:5GW5|rcsb pdb:6KRD|rcsb pdb:6KRE|rcsb pdb:6KS6|rcsb pdb:6KS7|rcsb pdb:6KS8|reactome:R-SCE-390471|reactome:R-SCE-6814122|dip:DIP-6753N|mint:P39078	-	-	crc64:F01146D76F4E850C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:qOkzIuloaWW88apb9JH2DT/Bnuk9606	rogid:GCSpoIEgtQxu/8dbncxp/4AXEls559292	intact-crc:E2D6A1462B4086C2|rigid:iQuVQOjFrxdRxUi15OftIUlJaN0	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q13422-7	uniprotkb:P25372	intact:EBI-11522367|ensembl:ENSP00000352123|ensembl:ENSP00000413025	intact:EBI-19616|uniprotkb:D6VR84|ensemblfungi:YCR083W	psi-mi:q13422-7(display_long)|uniprotkb:IKZF1(gene name)|psi-mi:IKZF1(display_short)|uniprotkb:IK1(gene name synonym)|uniprotkb:IKAROS(gene name synonym)|uniprotkb:Ikaros family zinc finger protein 1(gene name synonym)|uniprotkb:LYF1(gene name synonym)|uniprotkb:Lymphoid transcription factor LyF-1(gene name synonym)|uniprotkb:ZNFN1A1(gene name synonym)	psi-mi:trx3_yeast(display_long)|uniprotkb:TRX3(gene name)|psi-mi:TRX3(display_short)|uniprotkb:YCR83W(orf name)|uniprotkb:YCR083W(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551384|imex:IM-24995-3417	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-745305(isoform-parent)|ensembl:ENSG00000185811(gene)|ensembl:ENST00000359197(transcript)|ensembl:ENST00000439701(transcript)|uniprotkb:Q13422-7(isoform-parent)	interpro:IPR036249|refseq:NP_010006.1|sgd:S000000679|interpro:IPR017937|interpro:IPR013766(Thioredoxin domain)|rcsb pdb:2OE0|rcsb pdb:2OE1|rcsb pdb:2OE3|ensemblfungi:YCR083W(gene)|ensemblfungi:YCR083W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0015036"(disulfide oxidoreductase activity)|go:"GO:0034599"(cellular response to oxidative stress)|rcsb pdb:5YKW	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:ou/ovXYoMneBNVp4pj38VxenfyY9606	rogid:g0xjGf9GvJRl8iv2qoT5tOs7jXI559292	intact-crc:91381229E945819C|rigid:hAtZFbHwprHaYM4ZMSZuJSh4SWk	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P23059	uniprotkb:Q13422-7	intact:EBI-10950|ensemblfungi:YCR020C-A|uniprotkb:D6VR29	intact:EBI-11522367|ensembl:ENSP00000352123|ensembl:ENSP00000413025	psi-mi:naa38_yeast(display_long)|uniprotkb:MAK31(gene name)|psi-mi:MAK31(display_short)|uniprotkb:YCR020C-A(locus name)|uniprotkb:YCR20C-A(orf name)|uniprotkb:L-A virus GAG protein N-acetyltransferase subunit MAK31(gene name synonym)|uniprotkb:Maintenance of killer protein 31(gene name synonym)|uniprotkb:NAA38(gene name synonym)|uniprotkb:N-terminal acetyltransferase C complex subunit MAK31(gene name synonym)	psi-mi:q13422-7(display_long)|uniprotkb:IKZF1(gene name)|psi-mi:IKZF1(display_short)|uniprotkb:IK1(gene name synonym)|uniprotkb:IKAROS(gene name synonym)|uniprotkb:Ikaros family zinc finger protein 1(gene name synonym)|uniprotkb:LYF1(gene name synonym)|uniprotkb:Lymphoid transcription factor LyF-1(gene name synonym)|uniprotkb:ZNFN1A1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551416|imex:IM-24995-3425	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YCR020C-A(gene)|ensemblfungi:YCR020C-A_mRNA(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005688"(U6 snRNP)|go:"GO:0005829"(cytosol)|go:"GO:0006474"(N-terminal protein amino acid acetylation)|go:"GO:0016070"(RNA metabolic process)|go:"GO:0031417"(NatC complex)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071011"(precatalytic spliceosome)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR034110|rcsb pdb:6YGA|rcsb pdb:6YGB|rcsb pdb:6YGC|rcsb pdb:6YGD|refseq:NP_009948.1|sgd:S000000614|mint:P23059|dip:DIP-1429N	intact:EBI-745305(isoform-parent)|ensembl:ENSG00000185811(gene)|ensembl:ENST00000359197(transcript)|ensembl:ENST00000439701(transcript)|uniprotkb:Q13422-7(isoform-parent)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:VUwG0xxj0NeyZKANRYCAgJGuqs8559292	rogid:ou/ovXYoMneBNVp4pj38VxenfyY9606	intact-crc:D83F1498CA5BA3BE|rigid:VoFNN/v7hsuD62HSV31gHLpXIy8	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q13422-7	uniprotkb:P32529	intact:EBI-11522367|ensembl:ENSP00000352123|ensembl:ENSP00000413025	intact:EBI-15756|uniprotkb:D6VWN4|ensemblfungi:YJR063W	psi-mi:q13422-7(display_long)|uniprotkb:IKZF1(gene name)|psi-mi:IKZF1(display_short)|uniprotkb:IK1(gene name synonym)|uniprotkb:IKAROS(gene name synonym)|uniprotkb:Ikaros family zinc finger protein 1(gene name synonym)|uniprotkb:LYF1(gene name synonym)|uniprotkb:Lymphoid transcription factor LyF-1(gene name synonym)|uniprotkb:ZNFN1A1(gene name synonym)	psi-mi:rpa12_yeast(display_long)|uniprotkb:RPA12(gene name)|psi-mi:RPA12(display_short)|uniprotkb:RRN4(gene name synonym)|uniprotkb:YJR063W(locus name)|uniprotkb:J1747(orf name)|uniprotkb:DNA-directed RNA polymerase I 13.7 kDa polypeptide(gene name synonym)|uniprotkb:A12(gene name synonym)|uniprotkb:A12.2(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551412|imex:IM-24995-3424	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-745305(isoform-parent)|ensembl:ENSG00000185811(gene)|ensembl:ENST00000359197(transcript)|ensembl:ENST00000439701(transcript)|uniprotkb:Q13422-7(isoform-parent)	refseq:NP_012597.1|sgd:S000003824|dip:DIP-236N|mint:P32529|ensemblfungi:YJR063W(gene)|ensemblfungi:YJR063W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001054"(RNA polymerase I activity)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006363"(termination of RNA polymerase I transcription)|go:"GO:0006379"(mRNA cleavage)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042790"(nucleolar large rRNA transcription by RNA polymerase I)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR001222(Zinc finger, TFIIS-type)|interpro:IPR001529(DNA-directed RNA polymerase, M/15 kDa subunit)|interpro:IPR012164(DNA-directed RNA polymerase, subunit C11/M/9)|interpro:IPR019761|interpro:IPR034004|rcsb pdb:4C2M|rcsb pdb:4C3H|rcsb pdb:4C3I|rcsb pdb:4C3J|rcsb pdb:4YM7|rcsb pdb:5G5L|rcsb pdb:5LMX|rcsb pdb:5M3F|rcsb pdb:5M3M|rcsb pdb:5M5W|rcsb pdb:5M5X|rcsb pdb:5M5Y|rcsb pdb:5M64|rcsb pdb:5N5Y|rcsb pdb:5N5Z|rcsb pdb:5N60|rcsb pdb:5N61|rcsb pdb:5OA1|rcsb pdb:5W5Y|rcsb pdb:5W64|rcsb pdb:5W65|rcsb pdb:5W66|rcsb pdb:6H67|rcsb pdb:6H68|rcsb pdb:6HKO|rcsb pdb:6HLQ|rcsb pdb:6HLR|rcsb pdb:6HLS|rcsb pdb:6RQH|rcsb pdb:6RQL|rcsb pdb:6RQT|rcsb pdb:6RRD|rcsb pdb:6RUI|rcsb pdb:6RUO|rcsb pdb:6RWE|rcsb pdb:6TPS|reactome:R-SCE-73762|reactome:R-SCE-73772	-	-	crc64:D79372070819987C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:ou/ovXYoMneBNVp4pj38VxenfyY9606	rogid:B0Zmf643W8DtAQteaDk8PVvdqW4559292	intact-crc:3308CA3AADB2D568|rigid:OkVugayMDgkvP4sET1tDl42XLrc	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q13422-7	uniprotkb:P36009	intact:EBI-11522367|ensembl:ENSP00000352123|ensembl:ENSP00000413025	intact:EBI-5844|ensemblfungi:YKL078W|uniprotkb:Q07040|uniprotkb:D6VXK9	psi-mi:q13422-7(display_long)|uniprotkb:IKZF1(gene name)|psi-mi:IKZF1(display_short)|uniprotkb:IK1(gene name synonym)|uniprotkb:IKAROS(gene name synonym)|uniprotkb:Ikaros family zinc finger protein 1(gene name synonym)|uniprotkb:LYF1(gene name synonym)|uniprotkb:Lymphoid transcription factor LyF-1(gene name synonym)|uniprotkb:ZNFN1A1(gene name synonym)	psi-mi:dhr2_yeast(display_long)|uniprotkb:DHR2(gene name)|psi-mi:DHR2(display_short)|uniprotkb:YKL078W(locus name)|uniprotkb:YKL408(orf name)|uniprotkb:DEAH box RNA helicase DHR2(gene name synonym)|uniprotkb:Helicase JA2(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551396|imex:IM-24995-3420	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-745305(isoform-parent)|ensembl:ENSG00000185811(gene)|ensembl:ENST00000359197(transcript)|ensembl:ENST00000439701(transcript)|uniprotkb:Q13422-7(isoform-parent)	ensemblfungi:YKL078W(gene)|ensemblfungi:YKL078W_mRNA(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|refseq:NP_012845.1|sgd:S000001561|dip:DIP-6424N|mint:P36009|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417	-	-	crc64:AAFA78B5F6215D89	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:ou/ovXYoMneBNVp4pj38VxenfyY9606	rogid:UneKv9+4eIsC09fOzm8AvKCOCVs559292	intact-crc:75A7CC097636D489|rigid:FDHu/DRyfeVGom6qYipoARsDdRE	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q13422-7	uniprotkb:P39518	intact:EBI-11522367|ensembl:ENSP00000352123|ensembl:ENSP00000413025	intact:EBI-10082|uniprotkb:D3DLR3|ensemblfungi:YER015W	psi-mi:q13422-7(display_long)|uniprotkb:IKZF1(gene name)|psi-mi:IKZF1(display_short)|uniprotkb:IK1(gene name synonym)|uniprotkb:IKAROS(gene name synonym)|uniprotkb:Ikaros family zinc finger protein 1(gene name synonym)|uniprotkb:LYF1(gene name synonym)|uniprotkb:Lymphoid transcription factor LyF-1(gene name synonym)|uniprotkb:ZNFN1A1(gene name synonym)	psi-mi:lcf2_yeast(display_long)|uniprotkb:YER015W(locus name)|uniprotkb:FAA2(gene name)|psi-mi:FAA2(display_short)|uniprotkb:FAM1(gene name synonym)|uniprotkb:Long-chain acyl-CoA synthetase 2(gene name synonym)|uniprotkb:Fatty acid activator 2(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551404|imex:IM-24995-3422	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-745305(isoform-parent)|ensembl:ENSG00000185811(gene)|ensembl:ENST00000359197(transcript)|ensembl:ENST00000439701(transcript)|uniprotkb:Q13422-7(isoform-parent)	sgd:S000000817|ensemblfungi:YER015W_mRNA(transcript)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0004467"(long-chain fatty acid-CoA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0015910"(long-chain fatty acid import into peroxisome)|go:"GO:0015916"(fatty-acyl-CoA transport)|go:"GO:0016020"(membrane)|go:"GO:0031956"(medium-chain fatty acid-CoA ligase activity)|go:"GO:0031957"(very long-chain fatty acid-CoA ligase activity)|go:"GO:0042760"(very long-chain fatty acid catabolic process)|go:"GO:0102391"(decanoate-CoA ligase activity)|ensemblfungi:YER015W(gene)|interpro:IPR020845|interpro:IPR000873(AMP-dependent synthetase and ligase)|reactome:R-SCE-75876|refseq:NP_010931.3|dip:DIP-6565N	-	-	crc64:1E023C18682805BC	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:ou/ovXYoMneBNVp4pj38VxenfyY9606	rogid:N0W+wPvCsl01y0k8hJZ156LztOo559292	intact-crc:2E389A485B6E307F|rigid:tr2RoegfWLDzWC6PNjVH9qBlufc	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q13422-7	uniprotkb:Q03338	intact:EBI-11522367|ensembl:ENSP00000352123|ensembl:ENSP00000413025	intact:EBI-421|uniprotkb:D6VT97|ensemblfungi:YDR473C	psi-mi:q13422-7(display_long)|uniprotkb:IKZF1(gene name)|psi-mi:IKZF1(display_short)|uniprotkb:IK1(gene name synonym)|uniprotkb:IKAROS(gene name synonym)|uniprotkb:Ikaros family zinc finger protein 1(gene name synonym)|uniprotkb:LYF1(gene name synonym)|uniprotkb:Lymphoid transcription factor LyF-1(gene name synonym)|uniprotkb:ZNFN1A1(gene name synonym)	psi-mi:prp3_yeast(display_long)|uniprotkb:PRP3(gene name)|psi-mi:PRP3(display_short)|uniprotkb:RNA3(gene name synonym)|uniprotkb:YDR473C(locus name)|uniprotkb:D8035.16(orf name)|uniprotkb:Pre-mRNA-splicing factor 3(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551400|imex:IM-24995-3421	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-745305(isoform-parent)|ensembl:ENSG00000185811(gene)|ensembl:ENST00000359197(transcript)|ensembl:ENST00000439701(transcript)|uniprotkb:Q13422-7(isoform-parent)	sgd:S000002881|refseq:NP_010761.3|ensemblfungi:YDR473C(gene)|ensemblfungi:YDR473C_mRNA(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|interpro:IPR010541(Protein of unknown function DUF1115)|interpro:IPR013881(Pre-mRNA-splicing factor 3)|interpro:IPR027104|rcsb pdb:3JCM|rcsb pdb:4YHU|rcsb pdb:4YHV|rcsb pdb:4YHW|rcsb pdb:5GAN|rcsb pdb:5GAP|rcsb pdb:5NRL|rcsb pdb:5ZWM|rcsb pdb:5ZWO|dip:DIP-5266N|mint:Q03338	-	-	crc64:E977FD9F708BDD91	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:ou/ovXYoMneBNVp4pj38VxenfyY9606	rogid:KE0Y/kRXTq9LXt4PGsKnRcY7Sqg559292	intact-crc:26E8D13988B0D2BD|rigid:sTPJqRmLHOwyDW1RvdBNcHNgQ4U	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q04307	uniprotkb:Q13422-7	intact:EBI-15858|uniprotkb:Q2VQW5|ensemblfungi:YDR045C|uniprotkb:D6VS33	intact:EBI-11522367|ensembl:ENSP00000352123|ensembl:ENSP00000413025	psi-mi:rpc10_yeast(display_long)|uniprotkb:RPC11(gene name)|psi-mi:RPC11(display_short)|uniprotkb:YDR045C(locus name)|uniprotkb:YD9609.01C(orf name)|uniprotkb:RNA polymerase III subunit C11(gene name synonym)|uniprotkb:DNA-directed RNA polymerases III 12.5 kDa polypeptide(gene name synonym)	psi-mi:q13422-7(display_long)|uniprotkb:IKZF1(gene name)|psi-mi:IKZF1(display_short)|uniprotkb:IK1(gene name synonym)|uniprotkb:IKAROS(gene name synonym)|uniprotkb:Ikaros family zinc finger protein 1(gene name synonym)|uniprotkb:LYF1(gene name synonym)|uniprotkb:Lymphoid transcription factor LyF-1(gene name synonym)|uniprotkb:ZNFN1A1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551408|imex:IM-24995-3423	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YDR045C(gene)|refseq:NP_010330.1|sgd:S000002452|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006386"(termination of RNA polymerase III transcription)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042779"(tRNA 3'-trailer cleavage)|go:"GO:0042797"(tRNA transcription by RNA polymerase III)|interpro:IPR001222(Zinc finger, TFIIS-type)|interpro:IPR001529(DNA-directed RNA polymerase, M/15 kDa subunit)|interpro:IPR012164(DNA-directed RNA polymerase, subunit C11/M/9)|interpro:IPR019761|interpro:IPR034014|rcsb pdb:3QT1|ensemblfungi:YDR045C_mRNA(transcript)|rcsb pdb:5FJ8|rcsb pdb:5FJ9|rcsb pdb:5FJA|rcsb pdb:6CNB|rcsb pdb:6CNC|rcsb pdb:6CND|rcsb pdb:6CNF|rcsb pdb:6EU0|rcsb pdb:6EU2|rcsb pdb:6EU3|rcsb pdb:6F40|rcsb pdb:6F41|rcsb pdb:6F42|rcsb pdb:6F44|rcsb pdb:6TUT|reactome:R-SCE-76061|reactome:R-SCE-76066|rcsb pdb:6EU1|dip:DIP-887N|mint:Q04307	intact:EBI-745305(isoform-parent)|ensembl:ENSG00000185811(gene)|ensembl:ENST00000359197(transcript)|ensembl:ENST00000439701(transcript)|uniprotkb:Q13422-7(isoform-parent)	-	crc64:E4AA802EC9F92230	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:G2fIQbptabHIUI224iPtTJF+dIs559292	rogid:ou/ovXYoMneBNVp4pj38VxenfyY9606	intact-crc:BAE74B4755A16BE3|rigid:AguOrpXzwc0g3NAN036O7vb92XI	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
intact:EBI-11522371	uniprotkb:Q13422-7	-	intact:EBI-11522367|ensembl:ENSP00000352123|ensembl:ENSP00000413025	psi-mi:yjr003c(display_short)|psi-mi:EBI-11522371(display_long)	psi-mi:q13422-7(display_long)|uniprotkb:IKZF1(gene name)|psi-mi:IKZF1(display_short)|uniprotkb:IK1(gene name synonym)|uniprotkb:IKAROS(gene name synonym)|uniprotkb:Ikaros family zinc finger protein 1(gene name synonym)|uniprotkb:LYF1(gene name synonym)|uniprotkb:Lymphoid transcription factor LyF-1(gene name synonym)|uniprotkb:ZNFN1A1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551432|imex:IM-24995-3429	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	-	intact:EBI-745305(isoform-parent)|ensembl:ENSG00000185811(gene)|ensembl:ENST00000359197(transcript)|ensembl:ENST00000439701(transcript)|uniprotkb:Q13422-7(isoform-parent)	-	no-uniprot-update:	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:dYGrrP3JnrXO2rj4v/nTT64la6A4932	rogid:ou/ovXYoMneBNVp4pj38VxenfyY9606	intact-crc:D3E98A462678A5CA|rigid:E0mitkr1eJGaEWkr0L13/d3MwQw	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q13422-7	uniprotkb:Q03233	intact:EBI-11522367|ensembl:ENSP00000352123|ensembl:ENSP00000413025	intact:EBI-27402|uniprotkb:D6W008|ensemblfungi:YMR184W	psi-mi:q13422-7(display_long)|uniprotkb:IKZF1(gene name)|psi-mi:IKZF1(display_short)|uniprotkb:IK1(gene name synonym)|uniprotkb:IKAROS(gene name synonym)|uniprotkb:Ikaros family zinc finger protein 1(gene name synonym)|uniprotkb:LYF1(gene name synonym)|uniprotkb:Lymphoid transcription factor LyF-1(gene name synonym)|uniprotkb:ZNFN1A1(gene name synonym)	psi-mi:add37_yeast(display_long)|uniprotkb:YM8010.14(orf name)|uniprotkb:YMR184W(locus name)|uniprotkb:ADD37(gene name)|psi-mi:ADD37(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551428|imex:IM-24995-3428	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-745305(isoform-parent)|ensembl:ENSG00000185811(gene)|ensembl:ENST00000359197(transcript)|ensembl:ENST00000439701(transcript)|uniprotkb:Q13422-7(isoform-parent)	sgd:S000004796|refseq:NP_013909.1|dip:DIP-3848N|ensemblfungi:YMR184W(gene)|ensemblfungi:YMR184W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:ou/ovXYoMneBNVp4pj38VxenfyY9606	rogid:1f4WwSzzLoaYs7mq9XrVap58RWE559292	intact-crc:DEE4BF0976EB0A79|rigid:Q741FjeixosXKGt7X2veqa1bpo0	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q13422-7	uniprotkb:P36534	intact:EBI-11522367|ensembl:ENSP00000352123|ensembl:ENSP00000413025	intact:EBI-15595|uniprotkb:D6W3J5|uniprotkb:Q6B277|ensemblfungi:YPL173W	psi-mi:q13422-7(display_long)|uniprotkb:IKZF1(gene name)|psi-mi:IKZF1(display_short)|uniprotkb:IK1(gene name synonym)|uniprotkb:IKAROS(gene name synonym)|uniprotkb:Ikaros family zinc finger protein 1(gene name synonym)|uniprotkb:LYF1(gene name synonym)|uniprotkb:Lymphoid transcription factor LyF-1(gene name synonym)|uniprotkb:ZNFN1A1(gene name synonym)	psi-mi:rm40_yeast(display_long)|uniprotkb:YPL173W(locus name)|uniprotkb:MRPL40(gene name)|psi-mi:MRPL40(display_short)|uniprotkb:YmL40(gene name synonym)|uniprotkb:Mitochondrial large ribosomal subunit protein uL24m(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551424|imex:IM-24995-3427	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-745305(isoform-parent)|ensembl:ENSG00000185811(gene)|ensembl:ENST00000359197(transcript)|ensembl:ENST00000439701(transcript)|uniprotkb:Q13422-7(isoform-parent)	refseq:NP_015152.1|sgd:S000006094|ensemblfungi:YPL173W(gene)|ensemblfungi:YPL173W_mRNA(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0006412"(translation)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR003256(Ribosomal protein L24)|interpro:IPR005824(KOW)|interpro:IPR005825(Ribosomal protein L24/L26, conserved site)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR014722(Translation protein SH3-like, subgroup)|rcsb pdb:3J6B|rcsb pdb:5MRC|rcsb pdb:5MRE|rcsb pdb:5MRF|dip:DIP-7947N|mint:P36534	-	-	crc64:D5BB2B7AE13ECBF9	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:ou/ovXYoMneBNVp4pj38VxenfyY9606	rogid:NDbI5dslWtZzVGLPfKQTxT2o/bc559292	intact-crc:DB83E0B3078ECE39|rigid:P3hHvaBL/xXDnJCNMpzj6COuUyc	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P32562	uniprotkb:Q13422-7	intact:EBI-4440|ensemblfungi:YMR001C|uniprotkb:D6VZH5	intact:EBI-11522367|ensembl:ENSP00000352123|ensembl:ENSP00000413025	psi-mi:cdc5_yeast(display_long)|uniprotkb:CDC5(gene name)|psi-mi:CDC5(display_short)|uniprotkb:MSD2(gene name synonym)|uniprotkb:PKX2(gene name synonym)|uniprotkb:YMR001C(locus name)|uniprotkb:YM8270.03C(orf name)	psi-mi:q13422-7(display_long)|uniprotkb:IKZF1(gene name)|psi-mi:IKZF1(display_short)|uniprotkb:IK1(gene name synonym)|uniprotkb:IKAROS(gene name synonym)|uniprotkb:Ikaros family zinc finger protein 1(gene name synonym)|uniprotkb:LYF1(gene name synonym)|uniprotkb:Lymphoid transcription factor LyF-1(gene name synonym)|uniprotkb:ZNFN1A1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551420|imex:IM-24995-3426	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YMR001C(gene)|ensemblfungi:YMR001C_mRNA(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0000922"(spindle pole)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0010458"(exit from mitosis)|go:"GO:0010696"(positive regulation of mitotic spindle pole body separation)|go:"GO:0019237"(centromeric DNA binding)|refseq:NP_013714.1|sgd:S000004603|reactome:R-SCE-6804115|reactome:R-SCE-156711|reactome:R-SCE-162658|reactome:R-SCE-2565942|dip:DIP-2321N|reactome:R-SCE-2500257|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0035025"(positive regulation of Rho protein signal transduction)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051301"(cell division)|go:"GO:0070194"(synaptonemal complex disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0110083"(positive regulation of protein localization to cell division site involved in mitotic actomyosin contractile ring assembly)|go:"GO:1902542"(regulation of protein localization to mitotic spindle pole body)|go:"GO:1903353"(regulation of nucleus organization)|go:"GO:1904750"(negative regulation of protein localization to nucleolus)|go:"GO:1905339"(positive regulation of cohesin unloading)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033695|interpro:IPR033701|interpro:IPR036947|rcsb pdb:6MF4|rcsb pdb:6MF5|rcsb pdb:6MF6	intact:EBI-745305(isoform-parent)|ensembl:ENSG00000185811(gene)|ensembl:ENST00000359197(transcript)|ensembl:ENST00000439701(transcript)|uniprotkb:Q13422-7(isoform-parent)	-	crc64:B5A25F1BBBEAA3DC	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:XXSkltYvBA9Zkh0Kr5s1znazUC0559292	rogid:ou/ovXYoMneBNVp4pj38VxenfyY9606	intact-crc:847F67970DC4C12B|rigid:HDP6+0UygbB4Z+9FmY++33zoPyc	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P40325	uniprotkb:Q13490	intact:EBI-23614|uniprotkb:D6VV46|ensemblfungi:YGR268C	intact:EBI-514538|uniprotkb:Q16516|uniprotkb:Q4TTG0|uniprotkb:B4E026|ensembl:ENSP00000227758|ensembl:ENSP00000477613	psi-mi:hua1_yeast(display_long)|uniprotkb:HUA1(gene name)|psi-mi:HUA1(display_short)|uniprotkb:YGR268C(locus name)	psi-mi:birc2_human(display_long)|uniprotkb:Inhibitor of apoptosis protein 2(gene name synonym)|uniprotkb:TNFR2-TRAF-signaling complex protein 2(gene name synonym)|uniprotkb:IAP homolog B(gene name synonym)|uniprotkb:RING finger protein 48(gene name synonym)|uniprotkb:BIRC2(gene name)|psi-mi:BIRC2(display_short)|uniprotkb:API1(gene name synonym)|uniprotkb:MIHB(gene name synonym)|uniprotkb:RNF48(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase BIRC2(gene name synonym)|uniprotkb:Cellular inhibitor of apoptosis 1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551448|imex:IM-24995-3433	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003500|refseq:NP_011784.3|dip:DIP-1987N|ensemblfungi:YGR268C(gene)|ensemblfungi:YGR268C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|interpro:IPR038910	refseq:NP_001157.1|refseq:NP_001243095.1|refseq:NP_001243092.1|dip:DIP-33485N|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0045471"(response to ethanol)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051087"(chaperone binding)|go:"GO:0051591"(response to cAMP)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060544"(regulation of necroptotic process)|go:"GO:0060546"(negative regulation of necroptotic process)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070266"(necroptotic process)|go:"GO:0070424"(regulation of nucleotide-binding oligomerization domain containing signaling pathway)|go:"GO:0098770"(FBXO family protein binding)|go:"GO:1901222"(regulation of NIK/NF-kappaB signaling)|go:"GO:1902443"(negative regulation of ripoptosome assembly involved in necroptotic process)|go:"GO:1902523"(positive regulation of protein K63-linked ubiquitination)|go:"GO:1902524"(positive regulation of protein K48-linked ubiquitination)|go:"GO:1902527"(positive regulation of protein monoubiquitination)|go:"GO:2000116"(regulation of cysteine-type endopeptidase activity)|go:"GO:2000377"(regulation of reactive oxygen species metabolic process)|interpro:IPR001315(Caspase Recruitment)|interpro:IPR001370(Proteinase inhibitor I32, inhibitor of apoptosis)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011029(DEATH-like)|interpro:IPR041933|mint:Q13490|rcsb pdb:1QBH|rcsb pdb:2L9M|rcsb pdb:3D9T|rcsb pdb:3D9U|rcsb pdb:3M1D|rcsb pdb:3MUP|rcsb pdb:3OZ1|rcsb pdb:3T6P|rcsb pdb:3UW4|rcsb pdb:4EB9|rcsb pdb:4HY4|rcsb pdb:4HY5|rcsb pdb:4KMN|rcsb pdb:4LGE|rcsb pdb:4LGU|rcsb pdb:4MTI|rcsb pdb:4MU7|rcsb pdb:5M6N|rcsb pdb:6EXW|rcsb pdb:6HPR|rcsb pdb:6W74|rcsb pdb:6W7O|rcsb pdb:6W8I|reactome:R-HSA-111465|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-5213460|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5668541|reactome:R-HSA-5675482|reactome:R-HSA-5676594|reactome:R-HSA-5689880|reactome:R-HSA-937041|ensembl:ENSG00000110330(gene)|ensembl:ENST00000227758(transcript)|ensembl:ENST00000613397(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001741"(XY body)|go:"GO:0001890"(placenta development)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0016740"(transferase activity)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034121"(regulation of toll-like receptor signaling pathway)|go:"GO:0035631"(CD40 receptor complex)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0039535"(regulation of RIG-I signaling pathway)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)	-	crc64:78029FD484168793	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:xliNG9XUWbYRd0Nbu+xzCgxNrAs559292	rogid:FOikzyDyDtlv2l69i/WNDNq674A9606	intact-crc:61EA4CE3D4DDF020|rigid:Pl0sRkozh4Fe0A0tmTVh9BsVWgY	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P39724	uniprotkb:Q13422-7	intact:EBI-2343154|uniprotkb:D6VPH0|ensemblfungi:YAL046C	intact:EBI-11522367|ensembl:ENSP00000352123|ensembl:ENSP00000413025	psi-mi:bol3_yeast(display_long)|uniprotkb:BOL3(gene name)|psi-mi:BOL3(display_short)|uniprotkb:AIM1(gene name synonym)|uniprotkb:Altered inheritance of mitochondria protein 1(gene name synonym)|uniprotkb:YAL046C(locus name)	psi-mi:q13422-7(display_long)|uniprotkb:IKZF1(gene name)|psi-mi:IKZF1(display_short)|uniprotkb:IK1(gene name synonym)|uniprotkb:IKAROS(gene name synonym)|uniprotkb:Ikaros family zinc finger protein 1(gene name synonym)|uniprotkb:LYF1(gene name synonym)|uniprotkb:Lymphoid transcription factor LyF-1(gene name synonym)|uniprotkb:ZNFN1A1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551436|imex:IM-24995-3430	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009353.1|sgd:S000000044|interpro:IPR002634(BolA-like protein)|interpro:IPR036065|mint:P39724|ensemblfungi:YAL046C(gene)|ensemblfungi:YAL046C_mRNA(transcript)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0106035"(protein maturation by [4Fe-4S] cluster transfer)	intact:EBI-745305(isoform-parent)|ensembl:ENSG00000185811(gene)|ensembl:ENST00000359197(transcript)|ensembl:ENST00000439701(transcript)|uniprotkb:Q13422-7(isoform-parent)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:MLrW6Iu4YKXf87O1cyx5bY03VdE559292	rogid:ou/ovXYoMneBNVp4pj38VxenfyY9606	intact-crc:0798B8FB300A91B4|rigid:lFaKlyvgqMNhBmdwnTwouFOxKOM	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q13490	uniprotkb:P32502	intact:EBI-514538|uniprotkb:Q16516|uniprotkb:Q4TTG0|uniprotkb:B4E026|ensembl:ENSP00000227758|ensembl:ENSP00000477613	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:birc2_human(display_long)|uniprotkb:Inhibitor of apoptosis protein 2(gene name synonym)|uniprotkb:TNFR2-TRAF-signaling complex protein 2(gene name synonym)|uniprotkb:IAP homolog B(gene name synonym)|uniprotkb:RING finger protein 48(gene name synonym)|uniprotkb:BIRC2(gene name)|psi-mi:BIRC2(display_short)|uniprotkb:API1(gene name synonym)|uniprotkb:MIHB(gene name synonym)|uniprotkb:RNF48(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase BIRC2(gene name synonym)|uniprotkb:Cellular inhibitor of apoptosis 1(gene name synonym)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551440|imex:IM-24995-3431	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001157.1|refseq:NP_001243095.1|refseq:NP_001243092.1|dip:DIP-33485N|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0045471"(response to ethanol)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051087"(chaperone binding)|go:"GO:0051591"(response to cAMP)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060544"(regulation of necroptotic process)|go:"GO:0060546"(negative regulation of necroptotic process)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070266"(necroptotic process)|go:"GO:0070424"(regulation of nucleotide-binding oligomerization domain containing signaling pathway)|go:"GO:0098770"(FBXO family protein binding)|go:"GO:1901222"(regulation of NIK/NF-kappaB signaling)|go:"GO:1902443"(negative regulation of ripoptosome assembly involved in necroptotic process)|go:"GO:1902523"(positive regulation of protein K63-linked ubiquitination)|go:"GO:1902524"(positive regulation of protein K48-linked ubiquitination)|go:"GO:1902527"(positive regulation of protein monoubiquitination)|go:"GO:2000116"(regulation of cysteine-type endopeptidase activity)|go:"GO:2000377"(regulation of reactive oxygen species metabolic process)|interpro:IPR001315(Caspase Recruitment)|interpro:IPR001370(Proteinase inhibitor I32, inhibitor of apoptosis)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011029(DEATH-like)|interpro:IPR041933|mint:Q13490|rcsb pdb:1QBH|rcsb pdb:2L9M|rcsb pdb:3D9T|rcsb pdb:3D9U|rcsb pdb:3M1D|rcsb pdb:3MUP|rcsb pdb:3OZ1|rcsb pdb:3T6P|rcsb pdb:3UW4|rcsb pdb:4EB9|rcsb pdb:4HY4|rcsb pdb:4HY5|rcsb pdb:4KMN|rcsb pdb:4LGE|rcsb pdb:4LGU|rcsb pdb:4MTI|rcsb pdb:4MU7|rcsb pdb:5M6N|rcsb pdb:6EXW|rcsb pdb:6HPR|rcsb pdb:6W74|rcsb pdb:6W7O|rcsb pdb:6W8I|reactome:R-HSA-111465|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-5213460|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5668541|reactome:R-HSA-5675482|reactome:R-HSA-5676594|reactome:R-HSA-5689880|reactome:R-HSA-937041|ensembl:ENSG00000110330(gene)|ensembl:ENST00000227758(transcript)|ensembl:ENST00000613397(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001741"(XY body)|go:"GO:0001890"(placenta development)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0016740"(transferase activity)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034121"(regulation of toll-like receptor signaling pathway)|go:"GO:0035631"(CD40 receptor complex)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0039535"(regulation of RIG-I signaling pathway)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731	-	-	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:FOikzyDyDtlv2l69i/WNDNq674A9606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:869A0F245A37C4FE|rigid:OzX/AG4aATDjYDYDEi8FO1Y3P2g	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P38339	uniprotkb:Q13490	intact:EBI-15065|uniprotkb:D6VQQ7|ensemblfungi:YBR260C	intact:EBI-514538|uniprotkb:Q16516|uniprotkb:Q4TTG0|uniprotkb:B4E026|ensembl:ENSP00000227758|ensembl:ENSP00000477613	psi-mi:rgd1_yeast(display_long)|uniprotkb:RGD1(gene name)|psi-mi:RGD1(display_short)|uniprotkb:YBR260C(locus name)|uniprotkb:YBR1728(orf name)|uniprotkb:Related GAP domain protein 1(gene name synonym)	psi-mi:birc2_human(display_long)|uniprotkb:Inhibitor of apoptosis protein 2(gene name synonym)|uniprotkb:TNFR2-TRAF-signaling complex protein 2(gene name synonym)|uniprotkb:IAP homolog B(gene name synonym)|uniprotkb:RING finger protein 48(gene name synonym)|uniprotkb:BIRC2(gene name)|psi-mi:BIRC2(display_short)|uniprotkb:API1(gene name synonym)|uniprotkb:MIHB(gene name synonym)|uniprotkb:RNF48(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase BIRC2(gene name synonym)|uniprotkb:Cellular inhibitor of apoptosis 1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551444|imex:IM-24995-3432	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009819.1|sgd:S000000464|ensemblfungi:YBR260C(gene)|ensemblfungi:YBR260C_mRNA(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005628"(prospore membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005933"(cellular bud)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007165"(signal transduction)|go:"GO:0010314"(phosphatidylinositol-5-phosphate binding)|go:"GO:0010447"(response to acidic pH)|go:"GO:0030479"(actin cortical patch)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043332"(mating projection tip)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|interpro:IPR000198(RhoGAP)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR027267|interpro:IPR031160|rcsb pdb:4WPC|rcsb pdb:5MY3|reactome:R-SCE-6798695|reactome:R-SCE-8980692|reactome:R-SCE-9013148|reactome:R-SCE-9013405|reactome:R-SCE-9013423|reactome:R-SCE-9035034|dip:DIP-4950N|mint:P38339	refseq:NP_001157.1|refseq:NP_001243095.1|refseq:NP_001243092.1|dip:DIP-33485N|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0045471"(response to ethanol)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051087"(chaperone binding)|go:"GO:0051591"(response to cAMP)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060544"(regulation of necroptotic process)|go:"GO:0060546"(negative regulation of necroptotic process)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070266"(necroptotic process)|go:"GO:0070424"(regulation of nucleotide-binding oligomerization domain containing signaling pathway)|go:"GO:0098770"(FBXO family protein binding)|go:"GO:1901222"(regulation of NIK/NF-kappaB signaling)|go:"GO:1902443"(negative regulation of ripoptosome assembly involved in necroptotic process)|go:"GO:1902523"(positive regulation of protein K63-linked ubiquitination)|go:"GO:1902524"(positive regulation of protein K48-linked ubiquitination)|go:"GO:1902527"(positive regulation of protein monoubiquitination)|go:"GO:2000116"(regulation of cysteine-type endopeptidase activity)|go:"GO:2000377"(regulation of reactive oxygen species metabolic process)|interpro:IPR001315(Caspase Recruitment)|interpro:IPR001370(Proteinase inhibitor I32, inhibitor of apoptosis)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011029(DEATH-like)|interpro:IPR041933|mint:Q13490|rcsb pdb:1QBH|rcsb pdb:2L9M|rcsb pdb:3D9T|rcsb pdb:3D9U|rcsb pdb:3M1D|rcsb pdb:3MUP|rcsb pdb:3OZ1|rcsb pdb:3T6P|rcsb pdb:3UW4|rcsb pdb:4EB9|rcsb pdb:4HY4|rcsb pdb:4HY5|rcsb pdb:4KMN|rcsb pdb:4LGE|rcsb pdb:4LGU|rcsb pdb:4MTI|rcsb pdb:4MU7|rcsb pdb:5M6N|rcsb pdb:6EXW|rcsb pdb:6HPR|rcsb pdb:6W74|rcsb pdb:6W7O|rcsb pdb:6W8I|reactome:R-HSA-111465|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-5213460|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5668541|reactome:R-HSA-5675482|reactome:R-HSA-5676594|reactome:R-HSA-5689880|reactome:R-HSA-937041|ensembl:ENSG00000110330(gene)|ensembl:ENST00000227758(transcript)|ensembl:ENST00000613397(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001741"(XY body)|go:"GO:0001890"(placenta development)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0016740"(transferase activity)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034121"(regulation of toll-like receptor signaling pathway)|go:"GO:0035631"(CD40 receptor complex)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0039535"(regulation of RIG-I signaling pathway)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)	-	crc64:711D9CC717E9111D	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:xHHGufxy5DvB8ngwbICIkYD3DA8559292	rogid:FOikzyDyDtlv2l69i/WNDNq674A9606	intact-crc:99011DC43B86D69A|rigid:HaBnP7Z3zycxAx+3jRtT2Z4LiN8	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P32502	uniprotkb:Q13554-3	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	intact:EBI-11523526|ensembl:ENSP00000351542	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:q13554-3(display_long)|uniprotkb:CAMK2B(gene name)|psi-mi:CAMK2B(display_short)|uniprotkb:CAM2(gene name synonym)|uniprotkb:CAMK2(gene name synonym)|uniprotkb:CAMKB(gene name synonym)|uniprotkb:Beta'E(isoform synonym)|uniprotkb:Beta1(isoform synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551464|imex:IM-24995-3437	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731	ensembl:ENSG00000058404(gene)|ensembl:ENST00000358707(transcript)|intact:EBI-1058722(isoform-parent)|uniprotkb:Q13554-3(isoform-parent)	-	crc64:A5409FAF1594854C	isoform-comment:"Ref.1 (AAD42036) sequence is in conflict in position: 316:A->V."	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	rogid:H/SPSRbW/NRcHPJs7Z2y6ESTrhM9606	intact-crc:F022A970A3550CF8|rigid:DKdWSpVJL+VPJ6ZusJRxw/O5DJ4	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q01976	uniprotkb:Q13490	intact:EBI-2344265|uniprotkb:D6VQB0|ensemblfungi:YBR111C	intact:EBI-514538|uniprotkb:Q16516|uniprotkb:Q4TTG0|uniprotkb:B4E026|ensembl:ENSP00000227758|ensembl:ENSP00000477613	psi-mi:adpp_yeast(display_long)|uniprotkb:YSA1(gene name)|psi-mi:YSA1(display_short)|uniprotkb:ADP-ribose diphosphatase(gene name synonym)|uniprotkb:Adenosine diphosphoribose pyrophosphatase(gene name synonym)|uniprotkb:ADP-ribose phosphohydrolase(gene name synonym)|uniprotkb:YBR0907(orf name)|uniprotkb:YBR111C(locus name)	psi-mi:birc2_human(display_long)|uniprotkb:Inhibitor of apoptosis protein 2(gene name synonym)|uniprotkb:TNFR2-TRAF-signaling complex protein 2(gene name synonym)|uniprotkb:IAP homolog B(gene name synonym)|uniprotkb:RING finger protein 48(gene name synonym)|uniprotkb:BIRC2(gene name)|psi-mi:BIRC2(display_short)|uniprotkb:API1(gene name synonym)|uniprotkb:MIHB(gene name synonym)|uniprotkb:RNF48(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase BIRC2(gene name synonym)|uniprotkb:Cellular inhibitor of apoptosis 1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551452|imex:IM-24995-3434	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009669.1|sgd:S000000315|interpro:IPR020084|interpro:IPR000086(NUDIX hydrolase, core)|interpro:IPR015797(NUDIX)|reactome:R-SCE-2393930|ensemblfungi:YBR111C(gene)|ensemblfungi:YBR111C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006753"(nucleoside phosphate metabolic process)|go:"GO:0019693"(ribose phosphate metabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0047631"(ADP-ribose diphosphatase activity)	refseq:NP_001157.1|refseq:NP_001243095.1|refseq:NP_001243092.1|dip:DIP-33485N|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0045471"(response to ethanol)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051087"(chaperone binding)|go:"GO:0051591"(response to cAMP)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060544"(regulation of necroptotic process)|go:"GO:0060546"(negative regulation of necroptotic process)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070266"(necroptotic process)|go:"GO:0070424"(regulation of nucleotide-binding oligomerization domain containing signaling pathway)|go:"GO:0098770"(FBXO family protein binding)|go:"GO:1901222"(regulation of NIK/NF-kappaB signaling)|go:"GO:1902443"(negative regulation of ripoptosome assembly involved in necroptotic process)|go:"GO:1902523"(positive regulation of protein K63-linked ubiquitination)|go:"GO:1902524"(positive regulation of protein K48-linked ubiquitination)|go:"GO:1902527"(positive regulation of protein monoubiquitination)|go:"GO:2000116"(regulation of cysteine-type endopeptidase activity)|go:"GO:2000377"(regulation of reactive oxygen species metabolic process)|interpro:IPR001315(Caspase Recruitment)|interpro:IPR001370(Proteinase inhibitor I32, inhibitor of apoptosis)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011029(DEATH-like)|interpro:IPR041933|mint:Q13490|rcsb pdb:1QBH|rcsb pdb:2L9M|rcsb pdb:3D9T|rcsb pdb:3D9U|rcsb pdb:3M1D|rcsb pdb:3MUP|rcsb pdb:3OZ1|rcsb pdb:3T6P|rcsb pdb:3UW4|rcsb pdb:4EB9|rcsb pdb:4HY4|rcsb pdb:4HY5|rcsb pdb:4KMN|rcsb pdb:4LGE|rcsb pdb:4LGU|rcsb pdb:4MTI|rcsb pdb:4MU7|rcsb pdb:5M6N|rcsb pdb:6EXW|rcsb pdb:6HPR|rcsb pdb:6W74|rcsb pdb:6W7O|rcsb pdb:6W8I|reactome:R-HSA-111465|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-5213460|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5668541|reactome:R-HSA-5675482|reactome:R-HSA-5676594|reactome:R-HSA-5689880|reactome:R-HSA-937041|ensembl:ENSG00000110330(gene)|ensembl:ENST00000227758(transcript)|ensembl:ENST00000613397(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001741"(XY body)|go:"GO:0001890"(placenta development)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0016740"(transferase activity)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034121"(regulation of toll-like receptor signaling pathway)|go:"GO:0035631"(CD40 receptor complex)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0039535"(regulation of RIG-I signaling pathway)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:tpdVT9ttt/pL+UevSr0zW+rfyIc559292	rogid:FOikzyDyDtlv2l69i/WNDNq674A9606	intact-crc:5C3F641036C66C7B|rigid:vhDiILxBzyjxGTbwEavei/yZJ00	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P12709	uniprotkb:Q13501	intact:EBI-7238|uniprotkb:D6VQJ0|ensemblfungi:YBR196C	intact:EBI-307104|uniprotkb:Q13446|uniprotkb:Q9BUV7|uniprotkb:Q9BVS6|uniprotkb:Q9UEU1|uniprotkb:A6NFN7|uniprotkb:B2R661|uniprotkb:B3KUW5|intact:EBI-28976133|ensembl:ENSP00000374455	psi-mi:g6pi_yeast(display_long)|uniprotkb:PGI1(gene name)|psi-mi:PGI1(display_short)|uniprotkb:YBR196C(locus name)|uniprotkb:YBR1406(orf name)|uniprotkb:Phosphoglucose isomerase(gene name synonym)|uniprotkb:Phosphohexose isomerase(gene name synonym)	psi-mi:sqstm_human(display_long)|uniprotkb:SQSTM1(gene name)|psi-mi:SQSTM1(display_short)|uniprotkb:ORCA(gene name synonym)|uniprotkb:OSIL(gene name synonym)|uniprotkb:Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa(gene name synonym)|uniprotkb:Ubiquitin-binding protein p62(gene name synonym)|uniprotkb:EBI3-associated protein of 60 kDa(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551456|imex:IM-24995-3435	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009755.1|sgd:S000000400|mint:P12709|dip:DIP-1605N|ensemblfungi:YBR196C(gene)|ensemblfungi:YBR196C_mRNA(transcript)|go:"GO:0004347"(glucose-6-phosphate isomerase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006096"(glycolytic process)|go:"GO:0048029"(monosaccharide binding)|go:"GO:0051156"(glucose 6-phosphate metabolic process)|interpro:IPR001672("Phosphoglucose isomerase (PGI)")|interpro:IPR018189|interpro:IPR023096|interpro:IPR035476|interpro:IPR035482|reactome:R-SCE-5628897|reactome:R-SCE-6798695|reactome:R-SCE-70171|reactome:R-SCE-70263	ensembl:ENST00000360718|ensembl:ENSP00000353944|ensembl:ENSP00000374455|ensembl:ENSG00000161011(gene)|ensembl:ENST00000389805(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0000423"(mitophagy)|go:"GO:0000932"(P-body)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002376"(immune system process)|go:"GO:0002931"(response to ischemia)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006914"(autophagy)|go:"GO:0006915"(apoptotic process)|go:"GO:0007032"(endosome organization)|go:"GO:0008104"(protein localization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016197"(endosomal transport)|go:"GO:0016234"(inclusion body)|go:"GO:0016235"(aggresome)|go:"GO:0016236"(macroautophagy)|go:"GO:0016605"(PML body)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030017"(sarcomere)|go:"GO:0030154"(cell differentiation)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035973"(aggrephagy)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046578"(regulation of Ras protein signal transduction)|go:"GO:0061635"(regulation of protein complex stability)|go:"GO:0061912"(selective autophagy)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:0097225"(sperm midpiece)|go:"GO:0097413"(Lewy body)|go:"GO:0098780"(response to mitochondrial depolarisation)|go:"GO:1900273"(positive regulation of long-term synaptic potentiation)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1905719"(protein localization to perinuclear region of cytoplasm)|interpro:IPR000270(Octicosapeptide/Phox/Bem1p)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR009060(UBA-like)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR033741|go:"GO:0044753"(amphisome)|interpro:IPR034866|interpro:IPR043145|mint:Q13501|rcsb pdb:1Q02|rcsb pdb:2JY7|rcsb pdb:2JY8|rcsb pdb:2K0B|rcsb pdb:2KNV|go:"GO:0044754"(autolysosome)|rcsb pdb:4MJS|rcsb pdb:4UF8|rcsb pdb:4UF9|go:"GO:0044877"(protein-containing complex binding)|rcsb pdb:5YP7|rcsb pdb:5YP8|rcsb pdb:5YPA|rcsb pdb:5YPB|rcsb pdb:5YPC|rcsb pdb:5YPE|rcsb pdb:5YPF|rcsb pdb:5YPG|rcsb pdb:5YPH|rcsb pdb:6JM4|rcsb pdb:6KHZ|rcsb pdb:6MJ7|rcsb pdb:6TGY|rcsb pdb:6TH3|reactome:R-HSA-205043|reactome:R-HSA-209543|reactome:R-HSA-209560|reactome:R-HSA-5205685|reactome:R-HSA-9020702|reactome:R-HSA-9664873|refseq:NP_001135770.1|refseq:NP_001135771.1|refseq:NP_003891.1|dip:DIP-34443N|refseq:XP_016865499.1	-	crc64:556D3D3B77EED052	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:hle82HMm3aAvYrUuuGoaxqyg/VA559292	rogid:paIcBLmyiv1+D9QMym5MY3yc8MI9606	intact-crc:DE1F8FA8E7E4DE54|rigid:qlvg6UNiNpdoIDTLjzlG09foy/w	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q13554-3	uniprotkb:P16622	intact:EBI-11523526|ensembl:ENSP00000351542	intact:EBI-8261|uniprotkb:D6W2N2|ensemblfungi:YOR176W	psi-mi:q13554-3(display_long)|uniprotkb:CAMK2B(gene name)|psi-mi:CAMK2B(display_short)|uniprotkb:CAM2(gene name synonym)|uniprotkb:CAMK2(gene name synonym)|uniprotkb:CAMKB(gene name synonym)|uniprotkb:Beta'E(isoform synonym)|uniprotkb:Beta1(isoform synonym)	psi-mi:hemh_yeast(display_long)|uniprotkb:YOR176W(locus name)|uniprotkb:HEM15(gene name)|psi-mi:HEM15(display_short)|uniprotkb:Protoheme ferro-lyase(gene name synonym)|uniprotkb:Heme synthase(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551460|imex:IM-24995-3436	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000058404(gene)|ensembl:ENST00000358707(transcript)|intact:EBI-1058722(isoform-parent)|uniprotkb:Q13554-3(isoform-parent)	sgd:S000005702|reactome:R-SCE-189451|refseq:NP_014819.3|dip:DIP-4133N|ensemblfungi:YOR176W(gene)|ensemblfungi:YOR176W_mRNA(transcript)|go:"GO:0004325"(ferrochelatase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006783"(heme biosynthetic process)|interpro:IPR001015(Ferrochelatase)|interpro:IPR019772|interpro:IPR033644|interpro:IPR033659|rcsb pdb:1L8X|rcsb pdb:1LBQ	-	isoform-comment:"Ref.1 (AAD42036) sequence is in conflict in position: 316:A->V."	crc64:F04E7C7AAD36C24F	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:H/SPSRbW/NRcHPJs7Z2y6ESTrhM9606	rogid:XIsqmtBuj9oH1aN0DT4zEfQ7u9Q559292	intact-crc:F6B07E001321C2E5|rigid:N6Dnldxy/SX+NigiURwyH6sVW3M	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P19955	uniprotkb:Q13643	intact:EBI-16295|ensemblfungi:YFR049W|uniprotkb:D6VTT2	intact:EBI-741101|ensembl:ENSP00000362107|uniprotkb:Q6I9T0|uniprotkb:Q9BVA2|uniprotkb:D3DPT6	psi-mi:rt31_yeast(display_long)|uniprotkb:YFR049W(locus name)|uniprotkb:YMR31(gene name)|psi-mi:YMR31(display_short)	psi-mi:fhl3_human(display_long)|uniprotkb:FHL3(gene name)|psi-mi:FHL3(display_short)|uniprotkb:SLIM2(gene name synonym)|uniprotkb:Skeletal muscle LIM-protein 2(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551480|imex:IM-24995-3441	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000001945|ensemblfungi:YFR049W(gene)|ensemblfungi:YFR049W_mRNA(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005761"(mitochondrial ribosome)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006103"(2-oxoglutarate metabolic process)|interpro:IPR020373|go:"GO:0009353"(mitochondrial oxoglutarate dehydrogenase complex)|refseq:NP_116707.3|dip:DIP-5447N|mint:P19955	refseq:NP_004459.2|ensembl:ENSG00000183386(gene)|ensembl:ENST00000373016(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005925"(focal adhesion)|go:"GO:0007517"(muscle organ development)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0046872"(metal ion binding)|interpro:IPR001781(Zinc finger, LIM-type)|mint:Q13643|rcsb pdb:1WYH|rcsb pdb:2CUQ|rcsb pdb:2EHE|interpro:IPR037987|refseq:NP_001230807.1|dip:DIP-42030N	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:6QZyCc2+sOr3rdTswAxjMopU9/A559292	rogid:RAo+b/VgFSnHSbgR+zXuxJvypxM9606	intact-crc:D14B3301F08CDF57|rigid:5dxyVPMtLsP9iRozP88z/4JGD64	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q13643	uniprotkb:Q03020	intact:EBI-741101|ensembl:ENSP00000362107|uniprotkb:Q6I9T0|uniprotkb:Q9BVA2|uniprotkb:D3DPT6	intact:EBI-29901|uniprotkb:D6W3N2|ensemblfungi:YPL135W	psi-mi:fhl3_human(display_long)|uniprotkb:FHL3(gene name)|psi-mi:FHL3(display_short)|uniprotkb:SLIM2(gene name synonym)|uniprotkb:Skeletal muscle LIM-protein 2(gene name synonym)	psi-mi:isu1_yeast(display_long)|uniprotkb:YPL135W(locus name)|uniprotkb:Iron sulfur cluster scaffold protein 1(gene name synonym)|uniprotkb:ISU1(gene name)|psi-mi:ISU1(display_short)|uniprotkb:NUA1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551476|imex:IM-24995-3440	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004459.2|ensembl:ENSG00000183386(gene)|ensembl:ENST00000373016(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005925"(focal adhesion)|go:"GO:0007517"(muscle organ development)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0046872"(metal ion binding)|interpro:IPR001781(Zinc finger, LIM-type)|mint:Q13643|rcsb pdb:1WYH|rcsb pdb:2CUQ|rcsb pdb:2EHE|interpro:IPR037987|refseq:NP_001230807.1|dip:DIP-42030N	refseq:NP_015190.1|sgd:S000006056|dip:DIP-6556N|mint:Q03020|ensemblfungi:YPL135W(gene)|ensemblfungi:YPL135W_mRNA(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005506"(iron ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR002871(NIF system FeS cluster assembly, NifU, N-terminal)|interpro:IPR011339(ISC system FeS cluster assembly, IscU scaffold)|rcsb pdb:5T0V|rcsb pdb:5TRE|reactome:R-SCE-1362409	-	-	crc64:E240845A27D2E9EE	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:RAo+b/VgFSnHSbgR+zXuxJvypxM9606	rogid:zpPseOgZoK3cF+mCetzw05ct9Kc559292	intact-crc:C382859E2B321544|rigid:7JjiiY117RFpQJOaWkGL36p7ibY	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P28004	uniprotkb:Q13643	intact:EBI-20640|uniprotkb:D6VPI6|ensemblfungi:YAL032C	intact:EBI-741101|ensembl:ENSP00000362107|uniprotkb:Q6I9T0|uniprotkb:Q9BVA2|uniprotkb:D3DPT6	psi-mi:prp45_yeast(display_long)|uniprotkb:YAL032C(locus name)|uniprotkb:PRP45(gene name)|psi-mi:PRP45(display_short)|uniprotkb:FUN20(gene name synonym)	psi-mi:fhl3_human(display_long)|uniprotkb:FHL3(gene name)|psi-mi:FHL3(display_short)|uniprotkb:SLIM2(gene name synonym)|uniprotkb:Skeletal muscle LIM-protein 2(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551484|imex:IM-24995-3442	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009370.1|sgd:S000000030|ensemblfungi:YAL032C(gene)|ensemblfungi:YAL032C_mRNA(transcript)|go:"GO:0000350"(generation of catalytic spliceosome for second transesterification step)|go:"GO:0005634"(nucleus)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|interpro:IPR004015(SKIP/SNW)|interpro:IPR017862|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|dip:DIP-2774N|mint:P28004	refseq:NP_004459.2|ensembl:ENSG00000183386(gene)|ensembl:ENST00000373016(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005925"(focal adhesion)|go:"GO:0007517"(muscle organ development)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0046872"(metal ion binding)|interpro:IPR001781(Zinc finger, LIM-type)|mint:Q13643|rcsb pdb:1WYH|rcsb pdb:2CUQ|rcsb pdb:2EHE|interpro:IPR037987|refseq:NP_001230807.1|dip:DIP-42030N	-	crc64:FE5A724186D7FE84	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:qoHF1UsO3k+JOTOfigSuy2P84/k559292	rogid:RAo+b/VgFSnHSbgR+zXuxJvypxM9606	intact-crc:0E30335C0B7DB072|rigid:B/hjQikOusZuoTzjXLPHZWJuQHk	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q02821	uniprotkb:Q13557-8	intact:EBI-1797|uniprotkb:D6W0Z8|ensemblfungi:YNL189W	intact:EBI-11534483|ensembl:ENSP00000296402|ensembl:ENSP00000369098	psi-mi:ima1_yeast(display_long)|uniprotkb:SRP1(gene name)|psi-mi:SRP1(display_short)|uniprotkb:KAP60(gene name synonym)|uniprotkb:YNL189W(locus name)|uniprotkb:N1606(orf name)|uniprotkb:Karyopherin subunit alpha(gene name synonym)|uniprotkb:Karyopherin-60(gene name synonym)|uniprotkb:Serine-rich RNA polymerase I suppressor protein(gene name synonym)	psi-mi:q13557-8(display_long)|uniprotkb:CAMKD(gene name synonym)|uniprotkb:CAMK2D(gene name)|psi-mi:CAMK2D(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551468|imex:IM-24995-3438	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014210.1|sgd:S000005133|dip:DIP-728N|mint:Q02821|ensemblfungi:YNL189W(gene)|ensemblfungi:YNL189W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0031144"(proteasome localization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042564"(NLS-dependent protein nuclear import complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|rcsb pdb:1BK5|rcsb pdb:1BK6|rcsb pdb:1EE4|rcsb pdb:1EE5|rcsb pdb:1UN0|rcsb pdb:1WA5|rcsb pdb:2C1T|rcsb pdb:4PVZ|rcsb pdb:4XZR|rcsb pdb:5H2W|rcsb pdb:5H2X|rcsb pdb:5T94	intact:EBI-351018(isoform-parent)|ensembl:ENSG00000145349(gene)|ensembl:ENST00000296402(transcript)|ensembl:ENST00000379773(transcript)|uniprotkb:Q13557-8(isoform-parent)	-	crc64:8D3A0CB76F2E7C00	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:NyzC93xnBCb8DX/AH346lwg4u2A559292	rogid:44T/I8JdalScCNE5Vp/H+PnfdFo9606	intact-crc:3EF0EA86CCF637CE|rigid:Vp8do7OhElgVpphFHYjWx5CkT18	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q13620	uniprotkb:Q08273	intact:EBI-456067|uniprotkb:Q6PIE4|uniprotkb:Q6UP07|uniprotkb:B3KVX4|uniprotkb:B7Z5K8|uniprotkb:Q7Z673|uniprotkb:Q9BY37|uniprotkb:Q9UEB7|uniprotkb:Q9UED7|uniprotkb:B1APK5|ensembl:ENSP00000505084|ensembl:ENSP00000505176|ensembl:ENSP00000506259	intact:EBI-31686|uniprotkb:D6W1T5|ensemblfungi:YOL133W	psi-mi:cul4b_human(display_long)|uniprotkb:CUL4B(gene name)|psi-mi:CUL4B(display_short)|uniprotkb:KIAA0695(gene name synonym)	psi-mi:rbx1_yeast(display_long)|uniprotkb:E3 ubiquitin-protein ligase complex SCF subunit HRT1(gene name synonym)|uniprotkb:High level expression reduces Ty3 transposition protein 1(gene name synonym)|uniprotkb:HRT1(gene name)|psi-mi:HRT1(display_short)|uniprotkb:RBX1(gene name synonym)|uniprotkb:ROC1(gene name synonym)|uniprotkb:Regulator of cullins protein 1(gene name synonym)|uniprotkb:YOL133W(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551472|imex:IM-24995-3439	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001073341.1|refseq:NP_003579.3|ensembl:ENST00000371322|ensembl:ENSP00000360373|ensembl:ENST00000371323|ensembl:ENSP00000360374|ensembl:ENSP00000505084|ensembl:ENSP00000506259|ensembl:ENSP00000505176|refseq:XP_011529702.1|dip:DIP-31609N|ensembl:ENSG00000158290(gene)|ensembl:ENST00000680673(transcript)|ensembl:ENST00000681253(transcript)|ensembl:ENST00000681652(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031175"(neuron projection development)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031465"(Cul4B-RING E3 ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070914"(UV-damage excision repair)|reactome:R-HSA-5696394|reactome:R-HSA-5696395|reactome:R-HSA-5696400|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-8951664|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR033044|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|mint:Q13620|rcsb pdb:2DO7|rcsb pdb:4A0C|rcsb pdb:4A0L|rcsb pdb:4A64|reactome:R-HSA-110314	refseq:NP_014508.1|sgd:S000005493|dip:DIP-1373N|mint:Q08273|ensemblfungi:YOL133W(gene)|ensemblfungi:YOL133W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0035361"(Cul8-RING ubiquitin ligase complex)|go:"GO:0051301"(cell division)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097602"(cullin family protein binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR024766|reactome:R-SCE-5696395|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-68949|reactome:R-SCE-8854050|reactome:R-SCE-8951664|reactome:R-SCE-983168	-	-	crc64:A9C3193E48CAF881	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:D75aMBt3GaBdpBt5Mxsxk7yiRVg9606	rogid:7LBUfvb6zpWuPkbMDrEAnrMuJj8559292	intact-crc:4E83E2253CAE29BC|rigid:Vra33FHy1ONLghMcrhOtZAGNVTo	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
intact:EBI-11522371	uniprotkb:Q13829	-	intact:EBI-2505861|uniprotkb:B7Z6M4|uniprotkb:Q5TZQ1|ensembl:ENSP00000226225	psi-mi:yjr003c(display_short)|psi-mi:EBI-11522371(display_long)	psi-mi:bacd2_human(display_long)|uniprotkb:BACURD2(gene name synonym)|uniprotkb:BTB/POZ domain-containing protein TNFAIP1(gene name synonym)|uniprotkb:Protein B12(gene name synonym)|uniprotkb:TNFAIP1(gene name)|psi-mi:TNFAIP1(display_short)|uniprotkb:EDP1(gene name synonym)|uniprotkb:Tumor necrosis factor, alpha-induced protein 1, endothelial(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551496|imex:IM-24995-3445	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	-	refseq:NP_066960.1|ensembl:ENSG00000109079(gene)|ensembl:ENST00000226225(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006955"(immune response)|go:"GO:0016477"(cell migration)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030332"(cyclin binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0043149"(stress fiber assembly)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0051260"(protein homooligomerization)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR003131(Potassium channel, voltage dependent, Kv,  tetramerisation)|interpro:IPR011333(BTB/POZ fold)|mint:Q13829|reactome:R-HSA-9696264|reactome:R-HSA-9696270	-	no-uniprot-update:	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:dYGrrP3JnrXO2rj4v/nTT64la6A4932	rogid:8vM9HnNmkirDbJRETV/TeE8pONY9606	intact-crc:EEBB44401A889B07|rigid:9a3A/8NdlJMCCNvngc0qbz5NaMk	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P25372	uniprotkb:Q13643	intact:EBI-19616|uniprotkb:D6VR84|ensemblfungi:YCR083W	intact:EBI-741101|ensembl:ENSP00000362107|uniprotkb:Q6I9T0|uniprotkb:Q9BVA2|uniprotkb:D3DPT6	psi-mi:trx3_yeast(display_long)|uniprotkb:TRX3(gene name)|psi-mi:TRX3(display_short)|uniprotkb:YCR83W(orf name)|uniprotkb:YCR083W(locus name)	psi-mi:fhl3_human(display_long)|uniprotkb:FHL3(gene name)|psi-mi:FHL3(display_short)|uniprotkb:SLIM2(gene name synonym)|uniprotkb:Skeletal muscle LIM-protein 2(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551488|imex:IM-24995-3443	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR036249|refseq:NP_010006.1|sgd:S000000679|interpro:IPR017937|interpro:IPR013766(Thioredoxin domain)|rcsb pdb:2OE0|rcsb pdb:2OE1|rcsb pdb:2OE3|ensemblfungi:YCR083W(gene)|ensemblfungi:YCR083W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0015036"(disulfide oxidoreductase activity)|go:"GO:0034599"(cellular response to oxidative stress)|rcsb pdb:5YKW	refseq:NP_004459.2|ensembl:ENSG00000183386(gene)|ensembl:ENST00000373016(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005925"(focal adhesion)|go:"GO:0007517"(muscle organ development)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0046872"(metal ion binding)|interpro:IPR001781(Zinc finger, LIM-type)|mint:Q13643|rcsb pdb:1WYH|rcsb pdb:2CUQ|rcsb pdb:2EHE|interpro:IPR037987|refseq:NP_001230807.1|dip:DIP-42030N	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:g0xjGf9GvJRl8iv2qoT5tOs7jXI559292	rogid:RAo+b/VgFSnHSbgR+zXuxJvypxM9606	intact-crc:A263FFD3B07DE183|rigid:YeK0bnB8BkoATG8To/38UsoOSAI	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q13643	uniprotkb:P26343	intact:EBI-741101|ensembl:ENSP00000362107|uniprotkb:Q6I9T0|uniprotkb:Q9BVA2|uniprotkb:D3DPT6	intact:EBI-5489|uniprotkb:D6VX97|ensemblfungi:YKR034W	psi-mi:fhl3_human(display_long)|uniprotkb:FHL3(gene name)|psi-mi:FHL3(display_short)|uniprotkb:SLIM2(gene name synonym)|uniprotkb:Skeletal muscle LIM-protein 2(gene name synonym)	psi-mi:dal80_yeast(display_long)|uniprotkb:YKR034W(locus name)|uniprotkb:DAL80(gene name)|psi-mi:DAL80(display_short)|uniprotkb:UGA43(gene name synonym)|uniprotkb:Regulatory protein UGA43(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551492|imex:IM-24995-3444	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004459.2|ensembl:ENSG00000183386(gene)|ensembl:ENST00000373016(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005925"(focal adhesion)|go:"GO:0007517"(muscle organ development)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0046872"(metal ion binding)|interpro:IPR001781(Zinc finger, LIM-type)|mint:Q13643|rcsb pdb:1WYH|rcsb pdb:2CUQ|rcsb pdb:2EHE|interpro:IPR037987|refseq:NP_001230807.1|dip:DIP-42030N	refseq:NP_012959.1|sgd:S000001742|dip:DIP-2094N|ensemblfungi:YKR034W(gene)|ensemblfungi:YKR034W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042128"(nitrate assimilation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0090295"(nitrogen catabolite repression of transcription)|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR039355	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:RAo+b/VgFSnHSbgR+zXuxJvypxM9606	rogid:Qfoc7DZ+/Nwthc4Hf93+iwuYgVg559292	intact-crc:F81996805C754663|rigid:OUrGCbGSLz09l+RBSshd6fA3siM	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q02821	uniprotkb:Q13867	intact:EBI-1797|uniprotkb:D6W0Z8|ensemblfungi:YNL189W	intact:EBI-718504|uniprotkb:Q53F86|uniprotkb:Q9UER9|uniprotkb:B2R796|ensembl:ENSP00000261714	psi-mi:ima1_yeast(display_long)|uniprotkb:SRP1(gene name)|psi-mi:SRP1(display_short)|uniprotkb:KAP60(gene name synonym)|uniprotkb:YNL189W(locus name)|uniprotkb:N1606(orf name)|uniprotkb:Karyopherin subunit alpha(gene name synonym)|uniprotkb:Karyopherin-60(gene name synonym)|uniprotkb:Serine-rich RNA polymerase I suppressor protein(gene name synonym)	psi-mi:blmh_human(display_long)|uniprotkb:BLMH(gene name)|psi-mi:BLMH(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551508|imex:IM-24995-3448	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014210.1|sgd:S000005133|dip:DIP-728N|mint:Q02821|ensemblfungi:YNL189W(gene)|ensemblfungi:YNL189W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0031144"(proteasome localization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042564"(NLS-dependent protein nuclear import complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|rcsb pdb:1BK5|rcsb pdb:1BK6|rcsb pdb:1EE4|rcsb pdb:1EE5|rcsb pdb:1UN0|rcsb pdb:1WA5|rcsb pdb:2C1T|rcsb pdb:4PVZ|rcsb pdb:4XZR|rcsb pdb:5H2W|rcsb pdb:5H2X|rcsb pdb:5T94	refseq:NP_000377.1|ensembl:ENSG00000108578(gene)|ensembl:ENST00000261714(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004177"(aminopeptidase activity)|go:"GO:0004180"(carboxypeptidase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006508"(proteolysis)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0009636"(response to toxic substance)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043418"(homocysteine catabolic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000169(Peptidase, cysteine peptidase active site)|interpro:IPR004134(Peptidase C1B, bleomycin hydrolase)|interpro:IPR038765|mint:Q13867|rcsb pdb:1CB5|rcsb pdb:2CB5|reactome:R-HSA-983168	-	crc64:8D3A0CB76F2E7C00	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:NyzC93xnBCb8DX/AH346lwg4u2A559292	rogid:THDv63DC81eQzFvmyWs1rlCBMyk9606	intact-crc:ED8B788A74C182EB|rigid:mXEqsbkDTq9X7I09Sl2jwXhN0bE	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q13829	uniprotkb:P38011	intact:EBI-2505861|uniprotkb:B7Z6M4|uniprotkb:Q5TZQ1|ensembl:ENSP00000226225	intact:EBI-7405|uniprotkb:Q6LAA5|uniprotkb:D6VZT9|ensemblfungi:YMR116C	psi-mi:bacd2_human(display_long)|uniprotkb:BACURD2(gene name synonym)|uniprotkb:BTB/POZ domain-containing protein TNFAIP1(gene name synonym)|uniprotkb:Protein B12(gene name synonym)|uniprotkb:TNFAIP1(gene name)|psi-mi:TNFAIP1(display_short)|uniprotkb:EDP1(gene name synonym)|uniprotkb:Tumor necrosis factor, alpha-induced protein 1, endothelial(gene name synonym)	psi-mi:gblp_yeast(display_long)|uniprotkb:ASC1(gene name)|psi-mi:ASC1(display_short)|uniprotkb:CPC2(gene name synonym)|uniprotkb:Receptor of activated protein kinase C 1(gene name synonym)|uniprotkb:Receptor for activated C kinase(gene name synonym)|uniprotkb:Small ribosomal subunit protein RACK1(gene name synonym)|uniprotkb:YM9718.15C(orf name)|uniprotkb:YMR116C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551500|imex:IM-24995-3446	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_066960.1|ensembl:ENSG00000109079(gene)|ensembl:ENST00000226225(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006955"(immune response)|go:"GO:0016477"(cell migration)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030332"(cyclin binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0043149"(stress fiber assembly)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0051260"(protein homooligomerization)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR003131(Potassium channel, voltage dependent, Kv,  tetramerisation)|interpro:IPR011333(BTB/POZ fold)|mint:Q13829|reactome:R-HSA-9696264|reactome:R-HSA-9696270	refseq:NP_013834.1|sgd:S000004722|mint:P38011|dip:DIP-6465N|ensemblfungi:YMR116C(gene)|ensemblfungi:YMR116C_mRNA(transcript)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001965"(G-protein alpha-subunit binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005092"(GDP-dissociation inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0008104"(protein localization)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0043022"(ribosome binding)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0072344"(rescue of stalled ribosome)|go:"GO:0080135"(regulation of cellular response to stress)|go:"GO:1902660"(negative regulation of glucose mediated signaling pathway)|go:"GO:2001125"(negative regulation of translational frameshifting)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|rcsb pdb:1TRJ|rcsb pdb:3FRX|rcsb pdb:3J6X|rcsb pdb:3J6Y|rcsb pdb:3J77|rcsb pdb:3J78|rcsb pdb:3RFG|rcsb pdb:3RFH|rcsb pdb:4U3M|rcsb pdb:4U3N|rcsb pdb:4U3U|rcsb pdb:4U4N|rcsb pdb:4U4O|rcsb pdb:4U4Q|rcsb pdb:4U4R|rcsb pdb:4U4U|rcsb pdb:4U4Y|rcsb pdb:4U4Z|rcsb pdb:4U50|rcsb pdb:4U51|rcsb pdb:4U52|rcsb pdb:4U53|rcsb pdb:4U55|rcsb pdb:4U56|rcsb pdb:4U6F|rcsb pdb:4V6I|rcsb pdb:4V7R|rcsb pdb:4V88|rcsb pdb:4V8Y|rcsb pdb:4V8Z|rcsb pdb:4V92|rcsb pdb:5DAT|rcsb pdb:5DC3|rcsb pdb:5DGE|rcsb pdb:5DGF|rcsb pdb:5DGV|rcsb pdb:5FCI|rcsb pdb:5FCJ|rcsb pdb:5I4L|rcsb pdb:5JUO|rcsb pdb:5JUP|rcsb pdb:5JUS|rcsb pdb:5JUT|rcsb pdb:5JUU|rcsb pdb:5LYB|rcsb pdb:5M1J|rcsb pdb:5MC6|rcsb pdb:5MEI|rcsb pdb:5NDG|rcsb pdb:5NDV|rcsb pdb:5NDW|rcsb pdb:5OBM|rcsb pdb:5ON6|rcsb pdb:5TBW|rcsb pdb:5TGA|rcsb pdb:5TGM|rcsb pdb:6FAI|rcsb pdb:6GQ1|rcsb pdb:6GQB|rcsb pdb:6GQV|rcsb pdb:6HHQ|rcsb pdb:6I7O|rcsb pdb:6Q8Y|rcsb pdb:6RBE|rcsb pdb:6S47|rcsb pdb:6SNT|rcsb pdb:6SV4|rcsb pdb:6T4Q|rcsb pdb:6T7I|rcsb pdb:6T7T|rcsb pdb:6T83|rcsb pdb:6TB3|rcsb pdb:6TNU|rcsb pdb:6WDR|rcsb pdb:6WOO|rcsb pdb:6XIQ|rcsb pdb:6XIR|rcsb pdb:6Z6J|rcsb pdb:6Z6K|rcsb pdb:6ZCE|rcsb pdb:6ZU9|rcsb pdb:6ZVI|rcsb pdb:7A1G|rcsb pdb:7NRC|rcsb pdb:7NRD|rcsb pdb:7B7D	-	-	crc64:B9A5D4959A3C54FB	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:8vM9HnNmkirDbJRETV/TeE8pONY9606	rogid:T9ugPN58tGKmSOjRbv1bD1rznH8559292	intact-crc:918094E8C2C29079|rigid:JG78HbwXtpeoM+ZQxJKJuB72en0	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q13867	uniprotkb:P38340	intact:EBI-718504|uniprotkb:Q53F86|uniprotkb:Q9UER9|uniprotkb:B2R796|ensembl:ENSP00000261714	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:blmh_human(display_long)|uniprotkb:BLMH(gene name)|psi-mi:BLMH(display_short)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551504|imex:IM-24995-3447	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000377.1|ensembl:ENSG00000108578(gene)|ensembl:ENST00000261714(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004177"(aminopeptidase activity)|go:"GO:0004180"(carboxypeptidase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006508"(proteolysis)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0009636"(response to toxic substance)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043418"(homocysteine catabolic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000169(Peptidase, cysteine peptidase active site)|interpro:IPR004134(Peptidase C1B, bleomycin hydrolase)|interpro:IPR038765|mint:Q13867|rcsb pdb:1CB5|rcsb pdb:2CB5|reactome:R-HSA-983168	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F	-	-	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:THDv63DC81eQzFvmyWs1rlCBMyk9606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:FE2B8FF2A1B70315|rigid:yUwNVOPo80ORo/HA36C+4GlHasM	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q14566	uniprotkb:P40302	intact:EBI-374900|uniprotkb:Q13504|uniprotkb:Q99859|uniprotkb:B2R6H2|ensembl:ENSP00000264156	intact:EBI-13955|ensemblfungi:YMR314W|uniprotkb:D6W0E1	psi-mi:mcm6_human(display_long)|uniprotkb:MCM6(gene name)|psi-mi:MCM6(display_short)|uniprotkb:p105MCM(gene name synonym)	psi-mi:psa6_yeast(display_long)|uniprotkb:PRE5(gene name)|psi-mi:PRE5(display_short)|uniprotkb:YMR314W(locus name)|uniprotkb:YM9924.06(orf name)|uniprotkb:Proteasome component PRE5(gene name synonym)|uniprotkb:Macropain subunit PRE5(gene name synonym)|uniprotkb:Proteinase YSCE subunit PRE5(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit PRE5(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551528|imex:IM-24995-3453	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000264156(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0042555"(MCM complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902969"(mitotic DNA replication)|ensembl:ENSG00000076003(gene)|reactome:R-HSA-68962|reactome:R-HSA-69052|interpro:IPR008049(MCM protein 6)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041024|interpro:IPR041562|interpro:IPR001208(MCM)|mint:Q14566|rcsb pdb:2KLQ|rcsb pdb:2LE8|rcsb pdb:6XTX|rcsb pdb:6XTY|reactome:R-HSA-176187|reactome:R-HSA-176974|reactome:R-HSA-68867|reactome:R-HSA-68949|refseq:NP_005906.2|dip:DIP-31727N	rcsb pdb:4Y8T|rcsb pdb:4Y8U|rcsb pdb:4Y9Y|rcsb pdb:4Y9Z|rcsb pdb:4YA0|rcsb pdb:4YA1|rcsb pdb:4YA2|rcsb pdb:4YA3|rcsb pdb:4YA4|rcsb pdb:4YA5|rcsb pdb:4Y7X|rcsb pdb:4Y7Y|rcsb pdb:4Y80|rcsb pdb:4Y81|rcsb pdb:4Y82|rcsb pdb:4Y84|rcsb pdb:4Y8G|rcsb pdb:4Y8H|rcsb pdb:4Y8I|rcsb pdb:4Y8J|rcsb pdb:4Y8K|rcsb pdb:4Y8L|rcsb pdb:4Y8M|rcsb pdb:4Y8N|rcsb pdb:4Y8O|rcsb pdb:4Y8P|rcsb pdb:4Y8Q|rcsb pdb:4Y8R|rcsb pdb:4Y8S|rcsb pdb:5FG7|rcsb pdb:5FG9|rcsb pdb:5FGA|rcsb pdb:4YA7|rcsb pdb:4YA9|rcsb pdb:4Z1L|rcsb pdb:5A5B|rcsb pdb:5AHJ|rcsb pdb:5BOU|rcsb pdb:5BXL|rcsb pdb:5BXN|rcsb pdb:5CGF|rcsb pdb:5CGG|rcsb pdb:5CGH|rcsb pdb:5CGI|rcsb pdb:5CZ4|rcsb pdb:5CZ5|rcsb pdb:5CZ6|rcsb pdb:5CZ7|rcsb pdb:5CZ8|rcsb pdb:5CZ9|rcsb pdb:5CZA|rcsb pdb:5D0S|rcsb pdb:5D0T|rcsb pdb:5D0V|rcsb pdb:5D0W|rcsb pdb:5D0X|rcsb pdb:5D0Z|rcsb pdb:5DKI|rcsb pdb:5DKJ|rcsb pdb:5FGD|rcsb pdb:3HYE|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:3MG0|rcsb pdb:3MG4|rcsb pdb:3MG6|rcsb pdb:3MG7|rcsb pdb:3MG8|rcsb pdb:3NZJ|rcsb pdb:3NZW|rcsb pdb:3NZX|rcsb pdb:3OEU|rcsb pdb:3OEV|rcsb pdb:3OKJ|rcsb pdb:3SDI|rcsb pdb:3SDK|rcsb pdb:3SHJ|rcsb pdb:3TDD|rcsb pdb:3UN4|rcsb pdb:3UN8|rcsb pdb:3WXR|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:4EU2|rcsb pdb:4FZC|rcsb pdb:4FZG|rcsb pdb:4G4S|rcsb pdb:4GK7|rcsb pdb:4HNP|rcsb pdb:4HRC|rcsb pdb:4HRD|rcsb pdb:4INR|rcsb pdb:4INT|rcsb pdb:4INU|rcsb pdb:4J70|rcsb pdb:4JSQ|rcsb pdb:4JSU|rcsb pdb:4JT0|rcsb pdb:4LQI|rcsb pdb:4LTC|rcsb pdb:4NNN|rcsb pdb:4NNW|rcsb pdb:4NO1|rcsb pdb:4NO6|rcsb pdb:4NO8|rcsb pdb:4NO9|rcsb pdb:5FGE|rcsb pdb:5FGF|rcsb pdb:5FGG|rcsb pdb:5FGH|rcsb pdb:5FGI|rcsb pdb:5FHS|rcsb pdb:5JHR|rcsb pdb:5JHS|rcsb pdb:5L52|rcsb pdb:5L54|rcsb pdb:5L55|rcsb pdb:5L5A|rcsb pdb:5L5B|rcsb pdb:5L5D|rcsb pdb:5L5E|rcsb pdb:5L5F|rcsb pdb:5L5H|rcsb pdb:5L5I|rcsb pdb:5L5J|rcsb pdb:5L5O|rcsb pdb:5L5P|rcsb pdb:5L5Q|rcsb pdb:5L5R|rcsb pdb:4Q1S|rcsb pdb:4QBY|rcsb pdb:4QLQ|rcsb pdb:4QLS|rcsb pdb:4QLT|rcsb pdb:4QLU|rcsb pdb:4QLV|rcsb pdb:4QUX|rcsb pdb:4QUY|rcsb pdb:4QV0|rcsb pdb:4QV1|rcsb pdb:4QV3|rcsb pdb:4QV4|rcsb pdb:4QV5|rcsb pdb:4QV6|rcsb pdb:4QV7|rcsb pdb:4QV8|rcsb pdb:4QV9|rcsb pdb:4QVL|ensemblfungi:YMR314W(gene)|ensemblfungi:YMR314W_mRNA(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0042175"(nuclear outer membrane-endoplasmic reticulum membrane network)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR035144|rcsb pdb:1FNT|rcsb pdb:1G0U|rcsb pdb:1G65|rcsb pdb:1JD2|rcsb pdb:1RYP|rcsb pdb:1Z7Q|rcsb pdb:2F16|rcsb pdb:2FAK|rcsb pdb:2GPL|rcsb pdb:2ZCY|rcsb pdb:3BDM|rcsb pdb:3D29|rcsb pdb:3DY3|rcsb pdb:3DY4|rcsb pdb:3E47|rcsb pdb:3GPJ|rcsb pdb:3GPT|rcsb pdb:3GPW|rcsb pdb:4QVM|rcsb pdb:4QVN|rcsb pdb:4QVP|rcsb pdb:4QVQ|rcsb pdb:4QVV|rcsb pdb:4QVW|rcsb pdb:4QVY|rcsb pdb:4QW0|rcsb pdb:4QW1|rcsb pdb:4QW3|rcsb pdb:4QW4|rcsb pdb:4QW5|rcsb pdb:4QW6|rcsb pdb:4QW7|rcsb pdb:4QWF|rcsb pdb:4QWG|rcsb pdb:4QWI|rcsb pdb:4QWJ|rcsb pdb:4QWK|rcsb pdb:4QWL|rcsb pdb:4QWR|rcsb pdb:4QWS|rcsb pdb:4QWU|rcsb pdb:4QWX|rcsb pdb:4QXJ|rcsb pdb:4QZ0|rcsb pdb:4QZ1|rcsb pdb:4QZ2|rcsb pdb:4QZ3|rcsb pdb:4QZ4|rcsb pdb:4QZ5|rcsb pdb:4QZ6|rcsb pdb:4QZ7|rcsb pdb:4QZW|rcsb pdb:4QZX|rcsb pdb:4QZZ|rcsb pdb:4R00|rcsb pdb:4R02|rcsb pdb:4R17|rcsb pdb:4R18|rcsb pdb:4RUR|rcsb pdb:4V7O|rcsb pdb:4X6Z|rcsb pdb:4Y69|rcsb pdb:4Y6A|rcsb pdb:4Y6V|rcsb pdb:4Y6Z|rcsb pdb:4Y70|rcsb pdb:4Y74|rcsb pdb:4Y75|rcsb pdb:4Y77|rcsb pdb:4Y78|rcsb pdb:4Y7W|rcsb pdb:5LTT|rcsb pdb:5M2B|rcsb pdb:5MP9|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5NIF|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6G7F|rcsb pdb:6G8M|rcsb pdb:6G8N|rcsb pdb:6GOP|rcsb pdb:6H39|rcsb pdb:6HTB|rcsb pdb:6HTC|rcsb pdb:6HTD|rcsb pdb:6HTP|rcsb pdb:6HTR|rcsb pdb:6HUB|rcsb pdb:6HUC|rcsb pdb:6HUQ|rcsb pdb:6HUU|rcsb pdb:6HUV|rcsb pdb:6HV3|rcsb pdb:6HV4|rcsb pdb:6HV5|rcsb pdb:6HV7|rcsb pdb:6HVA|rcsb pdb:6HVR|rcsb pdb:6HVS|rcsb pdb:6HVT|rcsb pdb:6HVU|rcsb pdb:6HVV|rcsb pdb:5L5S|rcsb pdb:5L5T|rcsb pdb:5L5U|rcsb pdb:5L5V|rcsb pdb:5L5W|rcsb pdb:5L5X|rcsb pdb:5L5Y|rcsb pdb:5L5Z|rcsb pdb:5L60|rcsb pdb:5L61|rcsb pdb:5L62|rcsb pdb:5L63|rcsb pdb:5L64|rcsb pdb:5L65|rcsb pdb:5L66|rcsb pdb:5L67|rcsb pdb:5L68|rcsb pdb:5L69|rcsb pdb:5L6A|rcsb pdb:5L6B|rcsb pdb:5L6C|rcsb pdb:5LAI|rcsb pdb:5LAJ|rcsb pdb:6HVW|rcsb pdb:6HVX|rcsb pdb:6HVY|rcsb pdb:6HW0|rcsb pdb:6HW3|rcsb pdb:6HW4|rcsb pdb:6HW5|rcsb pdb:6HW6|rcsb pdb:6HW7|rcsb pdb:6HW8|rcsb pdb:6HW9|rcsb pdb:6HWA|rcsb pdb:6HWB|rcsb pdb:6HWC|rcsb pdb:6HWD|rcsb pdb:6HWE|rcsb pdb:6HWF|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2X|rcsb pdb:6J30|rcsb pdb:6ZOU|rcsb pdb:6ZP6|rcsb pdb:6ZP8|rcsb pdb:7LS5|rcsb pdb:7LS6|rcsb pdb:7LSX|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|rcsb pdb:6J2Q|refseq:NP_014045.1|sgd:S000004931|mint:P40302|dip:DIP-1528N	-	-	crc64:C43CBCC1C6B9E39E	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:gVpEwgfSwwxvP2T2CvCzIukthY49606	rogid:C9GPb0JAklkBz0t/YYqRMNEiQss559292	intact-crc:63A8F8F35F0D88CD|rigid:ka1v5tXFyE92Gheko7mHscWzz+U	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P32895	uniprotkb:Q14558	intact:EBI-9869|uniprotkb:D6VX20|ensemblfungi:YKL181W	intact:EBI-724449|uniprotkb:Q96H06|uniprotkb:B2R6M4	psi-mi:kpr1_yeast(display_long)|uniprotkb:PPS1(gene name synonym)|uniprotkb:PRP1(gene name synonym)|uniprotkb:PRPS(gene name synonym)|uniprotkb:PRPS1(gene name synonym)|uniprotkb:YKL181W(locus name)|uniprotkb:PRS1(gene name)|psi-mi:PRS1(display_short)|uniprotkb:Phosphoribosyl pyrophosphate synthase 1(gene name synonym)	psi-mi:kpra_human(display_long)|uniprotkb:39 kDa phosphoribosypyrophosphate synthase-associated protein(gene name synonym)|uniprotkb:PRPSAP1(gene name)|psi-mi:PRPSAP1(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551524|imex:IM-24995-3452	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012740.1|sgd:S000001664|ensemblfungi:YKL181W(gene)|ensemblfungi:YKL181W_mRNA(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0002189"(ribose phosphate diphosphokinase complex)|go:"GO:0004749"(ribose phosphate diphosphokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006015"(5-phosphoribose 1-diphosphate biosynthetic process)|go:"GO:0006164"(purine nucleotide biosynthetic process)|go:"GO:0009116"(nucleoside metabolic process)|go:"GO:0009156"(ribonucleoside monophosphate biosynthetic process)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016301"(kinase activity)|go:"GO:0031505"(fungal-type cell wall organization)|interpro:IPR000836(Phosphoribosyltransferase)|interpro:IPR000842(Phosphoribosyl pyrophosphate synthetase, conserved site)|interpro:IPR005946(Phosphoribosyl pyrophosphokinase)|interpro:IPR029057|interpro:IPR029099|reactome:R-SCE-73843|dip:DIP-4857N|mint:P32895	refseq:NP_002757.2|interpro:IPR005946(Phosphoribosyl pyrophosphokinase)|rcsb pdb:2C4K|go:"GO:0000287"(magnesium ion binding)|go:"GO:0002189"(ribose phosphate diphosphokinase complex)|go:"GO:0004749"(ribose phosphate diphosphokinase activity)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006015"(5-phosphoribose 1-diphosphate biosynthetic process)|go:"GO:0006139"(nucleobase-containing compound metabolic process)|go:"GO:0006164"(purine nucleotide biosynthetic process)|go:"GO:0042802"(identical protein binding)|interpro:IPR029057|interpro:IPR029099	-	crc64:F3E93ACB25E703FF	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:Ea45pOje4sjYrrU7ze4Af443yDk559292	rogid:7kFJX6q/3EcGnRNgAOImlr93Xys9606	intact-crc:D57AEFFD0C0151FC|rigid:qvyrZ/jsfWNgyC6izWzv5pYzHE4	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P27476	uniprotkb:Q14141-4	intact:EBI-12274|ensemblfungi:YGR159C|uniprotkb:D6VUT9	intact:EBI-11524882|ensembl:ENSP00000346169	psi-mi:nsr1_yeast(display_long)|uniprotkb:NSR1(gene name)|psi-mi:NSR1(display_short)|uniprotkb:YGR159C(locus name)|uniprotkb:G7001(orf name)|uniprotkb:p67(gene name synonym)	psi-mi:q14141-4(display_long)|uniprotkb:SEPTIN6(gene name)|psi-mi:SEPTIN6(display_short)|uniprotkb:KIAA0128(gene name synonym)|uniprotkb:SEP2(gene name synonym)|uniprotkb:SEPT6(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551512|imex:IM-24995-3449	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YGR159C(gene)|ensemblfungi:YGR159C_mRNA(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006364"(rRNA processing)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0043047"(single-stranded telomeric DNA binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034276|interpro:IPR035979|interpro:IPR034272|refseq:NP_011675.1|sgd:S000003391|mint:P27476|dip:DIP-5537N	ensembl:ENSG00000125354(gene)|ensembl:ENST00000354228(transcript)|intact:EBI-745901(isoform-parent)	-	crc64:90DEEE7BBC20BC0C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:q0/AgJC55iTpn/5kCsxal2kQ7Ls559292	rogid:QfLbdoBUG/Q5IYeoadJOtAK+kj49606	intact-crc:2323875F0CB74AB1|rigid:XNO6KTqFQk4W9Ap+A+2Gcj+WX/A	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q14145	uniprotkb:P17709	intact:EBI-751001|uniprotkb:B3KPD5|uniprotkb:Q8WTX1|uniprotkb:Q6LEP0|uniprotkb:Q9BPY9|intact:EBI-28976014|ensembl:ENSP00000171111|ensembl:ENSP00000377245	intact:EBI-8744|ensemblfungi:YCL040W|uniprotkb:D6VQX5	psi-mi:keap1_human(display_long)|uniprotkb:Cytosolic inhibitor of Nrf2(gene name synonym)|uniprotkb:Kelch-like protein 19(gene name synonym)|uniprotkb:KEAP1(gene name)|psi-mi:KEAP1(display_short)|uniprotkb:INRF2(gene name synonym)|uniprotkb:KIAA0132(gene name synonym)|uniprotkb:KLHL19(gene name synonym)	psi-mi:hxkg_yeast(display_long)|uniprotkb:GLK1(gene name)|psi-mi:GLK1(display_short)|uniprotkb:HOR3(gene name synonym)|uniprotkb:YCL040W(locus name)|uniprotkb:YCL40W(orf name)|uniprotkb:YCL312(orf name)|uniprotkb:Glucose kinase 1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551516|imex:IM-24995-3450	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_036421.2|refseq:NP_987096.1|ensembl:ENSP00000171111|ensembl:ENSP00000377245|refseq:XP_011526754.1|refseq:XP_005260230.1|refseq:XP_005260231.1|dip:DIP-42134N|ensembl:ENSG00000079999(gene)|ensembl:ENST00000171111(transcript)|ensembl:ENST00000393623(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0016234"(inclusion body)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030496"(midbody)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0034451"(centriolar satellite)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045604"(regulation of epidermal cell differentiation)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR017096(Kelch-like protein, gigaxonin)|interpro:IPR030563|mint:Q14145|rcsb pdb:1U6D|rcsb pdb:1ZGK|rcsb pdb:2FLU|rcsb pdb:3VNG|rcsb pdb:3VNH|rcsb pdb:3ZGC|rcsb pdb:3ZGD|rcsb pdb:4CXI|rcsb pdb:4CXJ|rcsb pdb:4CXT|rcsb pdb:4IFJ|rcsb pdb:4IFL|rcsb pdb:4IFN|rcsb pdb:4IN4|rcsb pdb:4IQK|rcsb pdb:4L7B|rcsb pdb:4L7C|rcsb pdb:4L7D|rcsb pdb:4N1B|rcsb pdb:4XMB|rcsb pdb:5DAD|rcsb pdb:5DAF|rcsb pdb:5F72|rcsb pdb:5GIT|rcsb pdb:5NLB|rcsb pdb:5WFL|rcsb pdb:5WFV|rcsb pdb:5WG1|rcsb pdb:5WHL|rcsb pdb:5WHO|rcsb pdb:5WIY|rcsb pdb:5X54|rcsb pdb:6FFM|rcsb pdb:6FMP|rcsb pdb:6FMQ|rcsb pdb:6HWS|rcsb pdb:6LRZ|rcsb pdb:6ROG|rcsb pdb:6SP1|rcsb pdb:6SP4|rcsb pdb:6T7V|rcsb pdb:6T7Z|rcsb pdb:6TG8|rcsb pdb:6TYM|rcsb pdb:6TYP|rcsb pdb:6UF0|rcsb pdb:6W66|rcsb pdb:6W67|rcsb pdb:6W68|rcsb pdb:6W69|rcsb pdb:6WCQ|rcsb pdb:6Z6A|rcsb pdb:7K28|rcsb pdb:7K29|rcsb pdb:7K2A|rcsb pdb:7K2B|rcsb pdb:7K2C|rcsb pdb:7K2D|rcsb pdb:7K2E|rcsb pdb:7K2F|rcsb pdb:7K2G|rcsb pdb:7K2H|rcsb pdb:7K2I|rcsb pdb:7K2J|rcsb pdb:7K2K|rcsb pdb:7K2L|rcsb pdb:7K2M|rcsb pdb:7K2N|rcsb pdb:7K2O|rcsb pdb:7K2P|rcsb pdb:7K2Q|rcsb pdb:7K2R|rcsb pdb:7K2S|reactome:R-HSA-5689880|reactome:R-HSA-8932339|reactome:R-HSA-8951664|reactome:R-HSA-983168|rcsb pdb:6V6Z	rcsb pdb:6PDT|reactome:R-SCE-170822|reactome:R-SCE-6798695|reactome:R-SCE-70171|go:"GO:0005536"(glucose binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006013"(mannose metabolic process)|go:"GO:0006096"(glycolytic process)|go:"GO:0008865"(fructokinase activity)|go:"GO:0019158"(mannokinase activity)|go:"GO:0046323"(glucose import)|go:"GO:0051156"(glucose 6-phosphate metabolic process)|interpro:IPR001312(Hexokinase)|interpro:IPR019807|interpro:IPR022672|interpro:IPR022673|interpro:IPR043129|rcsb pdb:6P4X|ensemblfungi:YCL040W(gene)|ensemblfungi:YCL040W_mRNA(transcript)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0004340"(glucokinase activity)|go:"GO:0005524"(ATP binding)|refseq:NP_009890.1|sgd:S000000545|mint:P17709|dip:DIP-525N	-	-	crc64:A7A417041D7A961F	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:3y/KqnUK+5nIyjhOEfkkthmP1OA9606	rogid:r6qkUttc6MTLWY6RYa26ZBCw2zg559292	intact-crc:3D0C6B8602A9752E|rigid:YG4NPEf1kZrlg9Su05LxmqNqT0s	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q14145	uniprotkb:P38109	intact:EBI-751001|uniprotkb:B3KPD5|uniprotkb:Q8WTX1|uniprotkb:Q6LEP0|uniprotkb:Q9BPY9|intact:EBI-28976014|ensembl:ENSP00000171111|ensembl:ENSP00000377245	intact:EBI-21638|uniprotkb:D6VQD5|ensemblfungi:YBR139W	psi-mi:keap1_human(display_long)|uniprotkb:Cytosolic inhibitor of Nrf2(gene name synonym)|uniprotkb:Kelch-like protein 19(gene name synonym)|uniprotkb:KEAP1(gene name)|psi-mi:KEAP1(display_short)|uniprotkb:INRF2(gene name synonym)|uniprotkb:KIAA0132(gene name synonym)|uniprotkb:KLHL19(gene name synonym)	psi-mi:yby9_yeast(display_long)|uniprotkb:YBR1015(orf name)|uniprotkb:YBR139W(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551520|imex:IM-24995-3451	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_036421.2|refseq:NP_987096.1|ensembl:ENSP00000171111|ensembl:ENSP00000377245|refseq:XP_011526754.1|refseq:XP_005260230.1|refseq:XP_005260231.1|dip:DIP-42134N|ensembl:ENSG00000079999(gene)|ensembl:ENST00000171111(transcript)|ensembl:ENST00000393623(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0016234"(inclusion body)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030496"(midbody)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0034451"(centriolar satellite)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045604"(regulation of epidermal cell differentiation)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR017096(Kelch-like protein, gigaxonin)|interpro:IPR030563|mint:Q14145|rcsb pdb:1U6D|rcsb pdb:1ZGK|rcsb pdb:2FLU|rcsb pdb:3VNG|rcsb pdb:3VNH|rcsb pdb:3ZGC|rcsb pdb:3ZGD|rcsb pdb:4CXI|rcsb pdb:4CXJ|rcsb pdb:4CXT|rcsb pdb:4IFJ|rcsb pdb:4IFL|rcsb pdb:4IFN|rcsb pdb:4IN4|rcsb pdb:4IQK|rcsb pdb:4L7B|rcsb pdb:4L7C|rcsb pdb:4L7D|rcsb pdb:4N1B|rcsb pdb:4XMB|rcsb pdb:5DAD|rcsb pdb:5DAF|rcsb pdb:5F72|rcsb pdb:5GIT|rcsb pdb:5NLB|rcsb pdb:5WFL|rcsb pdb:5WFV|rcsb pdb:5WG1|rcsb pdb:5WHL|rcsb pdb:5WHO|rcsb pdb:5WIY|rcsb pdb:5X54|rcsb pdb:6FFM|rcsb pdb:6FMP|rcsb pdb:6FMQ|rcsb pdb:6HWS|rcsb pdb:6LRZ|rcsb pdb:6ROG|rcsb pdb:6SP1|rcsb pdb:6SP4|rcsb pdb:6T7V|rcsb pdb:6T7Z|rcsb pdb:6TG8|rcsb pdb:6TYM|rcsb pdb:6TYP|rcsb pdb:6UF0|rcsb pdb:6W66|rcsb pdb:6W67|rcsb pdb:6W68|rcsb pdb:6W69|rcsb pdb:6WCQ|rcsb pdb:6Z6A|rcsb pdb:7K28|rcsb pdb:7K29|rcsb pdb:7K2A|rcsb pdb:7K2B|rcsb pdb:7K2C|rcsb pdb:7K2D|rcsb pdb:7K2E|rcsb pdb:7K2F|rcsb pdb:7K2G|rcsb pdb:7K2H|rcsb pdb:7K2I|rcsb pdb:7K2J|rcsb pdb:7K2K|rcsb pdb:7K2L|rcsb pdb:7K2M|rcsb pdb:7K2N|rcsb pdb:7K2O|rcsb pdb:7K2P|rcsb pdb:7K2Q|rcsb pdb:7K2R|rcsb pdb:7K2S|reactome:R-HSA-5689880|reactome:R-HSA-8932339|reactome:R-HSA-8951664|reactome:R-HSA-983168|rcsb pdb:6V6Z	sgd:S000000343|refseq:NP_009697.3|mint:P38109|dip:DIP-4923N|ensemblfungi:YBR139W(gene)|ensemblfungi:YBR139W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000328"(fungal-type vacuole lumen)|go:"GO:0004185"(serine-type carboxypeptidase activity)|go:"GO:0016236"(macroautophagy)|go:"GO:0017171"(serine hydrolase activity)|go:"GO:0031638"(zymogen activation)|go:"GO:0046938"(phytochelatin biosynthetic process)|interpro:IPR001563(Peptidase S10, serine carboxypeptidase)|interpro:IPR018202|interpro:IPR029058|interpro:IPR033124	-	-	crc64:AAB2806C8EE2EDE1	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:3y/KqnUK+5nIyjhOEfkkthmP1OA9606	rogid:x1bs6aRSmYGGBe4qebG37+9v4ek559292	intact-crc:29DA90F30AAEB68C|rigid:H05m15ogeIMWg5dFsLakXE30J8g	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P20133	uniprotkb:Q15008	intact:EBI-3559|uniprotkb:P32433|uniprotkb:D6W4H7|ensemblfungi:YPR176C	intact:EBI-359701|uniprotkb:E9PHI9|uniprotkb:A8K2E0|ensembl:ENSP00000295901|uniprotkb:Q6UV22	psi-mi:pgtb2_yeast(display_long)|uniprotkb:Geranylgeranyl transferase type II subunit beta(gene name synonym)|uniprotkb:Type II protein geranyl-geranyltransferase subunit beta(gene name synonym)|uniprotkb:YPT1/SEC4 proteins geranylgeranyltransferase subunit beta(gene name synonym)|uniprotkb:BET2(gene name)|psi-mi:BET2(display_short)|uniprotkb:YPR176C(locus name)|uniprotkb:P9705.12(orf name)	psi-mi:psmd6_human(display_long)|uniprotkb:PSMD6(gene name)|psi-mi:PSMD6(display_short)|uniprotkb:KIAA0107(gene name synonym)|uniprotkb:PFAAP4(gene name synonym)|uniprotkb:26S proteasome regulatory subunit S10(gene name synonym)|uniprotkb:p42A(gene name synonym)|uniprotkb:Proteasome regulatory particle subunit p44S10(gene name synonym)|uniprotkb:Phosphonoformate immuno-associated protein 4(gene name synonym)|uniprotkb:Breast cancer-associated protein SGA-113M(gene name synonym)|uniprotkb:26S proteasome regulatory subunit RPN7(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551548|imex:IM-24995-3458	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015502.1|sgd:S000006380|reactome:R-SCE-6803205|reactome:R-SCE-8873719|dip:DIP-2214N|ensemblfungi:YPR176C(gene)|ensemblfungi:YPR176C_mRNA(transcript)|go:"GO:0004663"(Rab geranylgeranyltransferase activity)|go:"GO:0005829"(cytosol)|go:"GO:0005968"(Rab-protein geranylgeranyltransferase complex)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0008270"(zinc ion binding)|go:"GO:0018342"(protein prenylation)|go:"GO:0018344"(protein geranylgeranylation)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001330(Prenyltransferase/squalene oxidase)|interpro:IPR008930(Terpenoid cylases/protein prenyltransferase alpha-alpha toroid)|interpro:IPR026873	refseq:NP_055629.1|ensembl:ENSG00000163636(gene)|ensembl:ENST00000295901(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019585|interpro:IPR035268|interpro:IPR036390|mint:Q15008|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4K|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSG|rcsb pdb:6MSH|reactome:R-HSA-5358346|reactome:R-HSA-1236978|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-1236974|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-69601|reactome:R-HSA-69481|refseq:NP_001258708.1|refseq:NP_001258709.1|refseq:NP_001258710.1|dip:DIP-27590N	-	crc64:6A9C44DFBE62AAFC	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Fxribu0N2yK6IA2GZDfO0YmqLAo559292	rogid:ULOM02v6J56vZLlAGn7wN3N6Efw9606	intact-crc:8C065DF70762B391|rigid:fL/QqaO2d11ZBD1qWxfd5l+y8o8	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P38340	uniprotkb:Q14749	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-744239|uniprotkb:Q9NNZ1|uniprotkb:Q9NS24|uniprotkb:Q5T8W2|ensembl:ENSP00000361894	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:gnmt_human(display_long)|uniprotkb:GNMT(gene name)|psi-mi:GNMT(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551544|imex:IM-24995-3457	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F	refseq:NP_061833.1|refseq:NP_001305794.1|ensembl:ENSG00000124713(gene)|ensembl:ENST00000372808(transcript)|go:"GO:0005542"(folic acid binding)|go:"GO:0005829"(cytosol)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0006111"(regulation of gluconeogenesis)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006555"(methionine metabolic process)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0016594"(glycine binding)|go:"GO:0017174"(glycine N-methyltransferase activity)|go:"GO:0032259"(methylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0046498"(S-adenosylhomocysteine metabolic process)|go:"GO:0046500"(S-adenosylmethionine metabolic process)|go:"GO:0051289"(protein homotetramerization)|go:"GO:1901052"(sarcosine metabolic process)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|interpro:IPR014369(Glycine N-methyltransferase)|interpro:IPR029063|interpro:IPR041698|rcsb pdb:1R74|rcsb pdb:2AZT|reactome:R-HSA-2408508|reactome:R-HSA-389661	-	crc64:66699F37B0013088	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:noj0nCgjJ1Dq079ycrwAu30a4AU9606	intact-crc:F225FC34C7A148D4|rigid:c92KjjiBa0Gz8YncPU5yIUfJv7M	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q14566	uniprotkb:P39946	intact:EBI-374900|uniprotkb:Q13504|uniprotkb:Q99859|uniprotkb:B2R6H2|ensembl:ENSP00000264156	intact:EBI-12838|uniprotkb:D6W2W9|ensemblfungi:YOR269W	psi-mi:mcm6_human(display_long)|uniprotkb:MCM6(gene name)|psi-mi:MCM6(display_short)|uniprotkb:p105MCM(gene name synonym)	psi-mi:lis1_yeast(display_long)|uniprotkb:PAC1(gene name)|psi-mi:PAC1(display_short)|uniprotkb:nudF homolog(gene name synonym)|uniprotkb:LIS1(gene name synonym)|uniprotkb:Lissencephaly-1 homolog(gene name synonym)|uniprotkb:YOR269W(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551532|imex:IM-24995-3454	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000264156(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0042555"(MCM complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902969"(mitotic DNA replication)|ensembl:ENSG00000076003(gene)|reactome:R-HSA-68962|reactome:R-HSA-69052|interpro:IPR008049(MCM protein 6)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041024|interpro:IPR041562|interpro:IPR001208(MCM)|mint:Q14566|rcsb pdb:2KLQ|rcsb pdb:2LE8|rcsb pdb:6XTX|rcsb pdb:6XTY|reactome:R-HSA-176187|reactome:R-HSA-176974|reactome:R-HSA-68867|reactome:R-HSA-68949|refseq:NP_005906.2|dip:DIP-31727N	ensemblfungi:YOR269W(gene)|ensemblfungi:YOR269W_mRNA(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007097"(nuclear migration)|go:"GO:0030473"(nuclear migration along microtubule)|go:"GO:0031023"(microtubule organizing center organization)|go:"GO:0042802"(identical protein binding)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0051012"(microtubule sliding)|go:"GO:0051301"(cell division)|go:"GO:0070840"(dynein complex binding)|go:"GO:1903033"(positive regulation of microtubule plus-end binding)|go:"GO:2000574"(obsolete regulation of microtubule motor activity)|go:"GO:2000582"(obsolete positive regulation of microtubule motor activity, plus-end-directed)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR017252(Dynein regulator)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|interpro:IPR037190|rcsb pdb:5VH9|rcsb pdb:5VLJ|refseq:NP_014912.1|sgd:S000005795|mint:P39946|dip:DIP-1485N	-	-	crc64:E667E4BA7602FB3B	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:gVpEwgfSwwxvP2T2CvCzIukthY49606	rogid:tyU5fR5V8csklk2QqAQHt3Mmz7c559292	intact-crc:A44671E98336CAAC|rigid:ph2S3f8CdLJnhy9N1oGHGPx3SBc	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q14596-2	uniprotkb:P89105	intact:EBI-11081753|ensembl:ENSP00000467816	intact:EBI-5283|uniprotkb:O14409|uniprotkb:Q07332|uniprotkb:Q08292|uniprotkb:D6W1S4|ensemblfungi:YOL145C	psi-mi:q14596-2(display_long)|uniprotkb:NBR1(gene name)|psi-mi:NBR1(display_short)|uniprotkb:1A13B(gene name synonym)|uniprotkb:Cell migration-inducing gene 19 protein(gene name synonym)|uniprotkb:KIAA0049(gene name synonym)|uniprotkb:M17S2(gene name synonym)|uniprotkb:Membrane component chromosome 17 surface marker 2(gene name synonym)|uniprotkb:Neighbor of BRCA1 gene 1 protein(gene name synonym)|uniprotkb:Protein 1A1-3B(gene name synonym)|uniprotkb:MIG19(orf name)	psi-mi:ctr9_yeast(display_long)|uniprotkb:CTR9(gene name)|psi-mi:CTR9(display_short)|uniprotkb:CDP1(gene name synonym)|uniprotkb:Cln three-requiring protein 9(gene name synonym)|uniprotkb:Centromere-binding factor 1-dependent protein 1(gene name synonym)|uniprotkb:YOL145C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551536|imex:IM-24995-3455	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-742698(isoform-parent)|ensembl:ENSG00000188554(gene)|ensembl:ENST00000589872(transcript)|uniprotkb:Q14596-2(isoform-parent)	refseq:NP_014496.2|sgd:S000005505|dip:DIP-2814N|mint:P89105|ensemblfungi:YOL145C(gene)|ensemblfungi:YOL145C_mRNA(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001015"(snoRNA transcription by RNA polymerase II)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006362"(transcription elongation from RNA polymerase I promoter)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016570"(histone modification)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0031126"("sno(s)RNA 3'-end processing")|go:"GO:0031938"(obsolete regulation of chromatin silencing at telomere)|go:"GO:0035327"|go:"GO:0045142"(triplex DNA binding)|go:"GO:0051569"(regulation of histone H3-K4 methylation)|go:"GO:0060260"(regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0090262"(regulation of transcription-coupled nucleotide-excision repair)|go:"GO:1901525"(negative regulation of mitophagy)|go:"GO:1990269"(RNA polymerase II C-terminal domain phosphoserine binding)|go:"GO:2001165"(positive regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues)|go:"GO:2001173"(regulation of histone H2B conserved C-terminal lysine ubiquitination)|go:"GO:2001209"(positive regulation of transcription elongation from RNA polymerase I promoter)|go:"GO:2001255"(positive regulation of histone H3-K36 trimethylation)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR031101|rcsb pdb:5ZYP|reactome:R-SCE-674695|reactome:R-SCE-75955	-	isoform-comment:No experimental confirmation available.	crc64:F794ECBAD26D4820	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:KrZKoabpN1yOvD3Bt6+CCN9Wv5g9606	rogid:85qAqldtQL8T7JBgNxrvAYtHhd0559292	intact-crc:5A3ABADF11FA98BC|rigid:LG3mv+dbVjN5SNCITI1CYwWPwyY	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P32502	uniprotkb:Q14749	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	intact:EBI-744239|uniprotkb:Q9NNZ1|uniprotkb:Q9NS24|uniprotkb:Q5T8W2|ensembl:ENSP00000361894	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:gnmt_human(display_long)|uniprotkb:GNMT(gene name)|psi-mi:GNMT(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551540|imex:IM-24995-3456	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731	refseq:NP_061833.1|refseq:NP_001305794.1|ensembl:ENSG00000124713(gene)|ensembl:ENST00000372808(transcript)|go:"GO:0005542"(folic acid binding)|go:"GO:0005829"(cytosol)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0006111"(regulation of gluconeogenesis)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006555"(methionine metabolic process)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0016594"(glycine binding)|go:"GO:0017174"(glycine N-methyltransferase activity)|go:"GO:0032259"(methylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0046498"(S-adenosylhomocysteine metabolic process)|go:"GO:0046500"(S-adenosylmethionine metabolic process)|go:"GO:0051289"(protein homotetramerization)|go:"GO:1901052"(sarcosine metabolic process)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|interpro:IPR014369(Glycine N-methyltransferase)|interpro:IPR029063|interpro:IPR041698|rcsb pdb:1R74|rcsb pdb:2AZT|reactome:R-HSA-2408508|reactome:R-HSA-389661	-	crc64:A5409FAF1594854C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	rogid:noj0nCgjJ1Dq079ycrwAu30a4AU9606	intact-crc:0C348437C4E1BD25|rigid:8x0vbouDfpgFXpuOOybPIvyDrhI	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q15025	uniprotkb:Q12259	intact:EBI-357849|uniprotkb:A4F1W8|uniprotkb:O76008|uniprotkb:Q96EL9|uniprotkb:Q99833|uniprotkb:Q9H1J3|uniprotkb:B7Z699|uniprotkb:Q6N077|ensembl:ENSP00000317891|ensembl:ENSP00000428187|ensembl:ENSP00000430760|uniprotkb:A4F1W9|uniprotkb:A4F1X2|uniprotkb:A4F1X4|uniprotkb:A4F1X5|uniprotkb:A4F1X6|uniprotkb:A4F1X7|uniprotkb:A4F1X9|uniprotkb:E7EPY1|uniprotkb:E7ET96|uniprotkb:Q05KP3|uniprotkb:Q05KP4	intact:EBI-30776|uniprotkb:D6VYA8|ensemblfungi:YLR108C	psi-mi:tnip1_human(display_long)|uniprotkb:TNIP1(gene name)|psi-mi:TNIP1(display_short)|uniprotkb:KIAA0113(gene name synonym)|uniprotkb:NAF1(gene name synonym)|uniprotkb:Nef-associated factor 1(gene name synonym)|uniprotkb:HIV-1 Nef-interacting protein(gene name synonym)|uniprotkb:Virion-associated nuclear shuttling protein(gene name synonym)|uniprotkb:Nip40-1(gene name synonym)|uniprotkb:A20-binding inhibitor of NF-kappa-B activation 1(gene name synonym)	psi-mi:yl108_yeast(display_long)|uniprotkb:L2913(orf name)|uniprotkb:YLR108C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551564|imex:IM-24995-3462	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006049.3|refseq:NP_001239319.1|refseq:NP_001239320.1|refseq:NP_001239321.1|refseq:NP_001239322.1|refseq:NP_001245383.1|dip:DIP-27577N|refseq:NP_001239315.1|ensembl:ENSG00000145901(gene)|ensembl:ENST00000315050(transcript)|ensembl:ENST00000521591(transcript)|ensembl:ENST00000522226(transcript)|go:"GO:0002755"(MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0006952"(defense response)|go:"GO:0006954"(inflammatory response)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0009101"(glycoprotein biosynthetic process)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0085032"(modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade)|go:"GO:1903003"(positive regulation of protein deubiquitination)|interpro:IPR033372|mint:Q15025|reactome:R-HSA-5689896|go:"GO:0051019"(mitogen-activated protein kinase binding)|refseq:NP_001239314.1|refseq:NP_001245384.1|refseq:NP_001245385.1|refseq:XP_006714814.1|refseq:XP_006714815.1	refseq:NP_013209.1|sgd:S000004098|dip:DIP-4075N|ensemblfungi:YLR108C(gene)|ensemblfungi:YLR108C_mRNA(transcript)|go:"GO:0005634"(nucleus)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:16Vjb5CuGTAbW2M22qbCxgXtV1o9606	rogid:CzknxXhhvgMp3J0/oi197EgZ05U559292	intact-crc:858DEE0CD5D8ADE8|rigid:cWMyQh0kOz3uytxWbjilqKqnh8o	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P32458	uniprotkb:Q15019-3	intact:EBI-4178|uniprotkb:D6VWP6|ensemblfungi:YJR076C	intact:EBI-11525407|ensembl:ENSP00000385109	psi-mi:cdc11_yeast(display_long)|uniprotkb:CDC11(gene name)|psi-mi:CDC11(display_short)|uniprotkb:PSL9(gene name synonym)|uniprotkb:YJR076C(locus name)|uniprotkb:J1833(orf name)	psi-mi:q15019-3(display_long)|uniprotkb:SEPTIN2(gene name)|psi-mi:SEPTIN2(display_short)|uniprotkb:DIFF6(gene name synonym)|uniprotkb:KIAA0158(gene name synonym)|uniprotkb:NEDD5(gene name synonym)|uniprotkb:Neural precursor cell expressed developmentally down-regulated protein 5(gene name synonym)|uniprotkb:SEPT2(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551552|imex:IM-24995-3459	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012610.1|sgd:S000003837|dip:DIP-1656N|mint:P32458|ensemblfungi:YJR076C(gene)|ensemblfungi:YJR076C_mRNA(transcript)|go:"GO:0000144"(cellular bud neck septin ring)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000915"(actomyosin contractile ring assembly)|go:"GO:0000917"(division septum assembly)|go:"GO:0001400"(mating projection base)|go:"GO:0003924"(GTPase activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005619"(ascospore wall)|go:"GO:0005628"(prospore membrane)|go:"GO:0005876"(spindle microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0005935"(cellular bud neck)|go:"GO:0005940"(septin ring)|go:"GO:0010314"(phosphatidylinositol-5-phosphate binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030011"(maintenance of cell polarity)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0032160"(septin filament array)|go:"GO:0032186"(cellular bud neck septin ring organization)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042802"(identical protein binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0072687"(meiotic spindle)|go:"GO:0097271"(protein localization to bud neck)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|rcsb pdb:5AR1	ensembl:ENST00000401990(transcript)|ensembl:ENSG00000168385(gene)|intact:EBI-741220(isoform-parent)|uniprotkb:Q15019-3(isoform-parent)	-	crc64:5CFFD4CD1F6C57D4	isoform-comment:No experimental confirmation available.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:KRcNMx6EOTmvHb+6u15UrVoyb3s559292	rogid:fBY0oYn+bn7aJbJr9OyZEpqkhLc9606	intact-crc:991BA1E85101FAF4|rigid:QIyrwTQRextVuKXuXcgYW43FQbQ	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q15025	uniprotkb:P28777	intact:EBI-357849|uniprotkb:A4F1W8|uniprotkb:O76008|uniprotkb:Q96EL9|uniprotkb:Q99833|uniprotkb:Q9H1J3|uniprotkb:B7Z699|uniprotkb:Q6N077|ensembl:ENSP00000317891|ensembl:ENSP00000428187|ensembl:ENSP00000430760|uniprotkb:A4F1W9|uniprotkb:A4F1X2|uniprotkb:A4F1X4|uniprotkb:A4F1X5|uniprotkb:A4F1X6|uniprotkb:A4F1X7|uniprotkb:A4F1X9|uniprotkb:E7EPY1|uniprotkb:E7ET96|uniprotkb:Q05KP3|uniprotkb:Q05KP4	intact:EBI-2906|uniprotkb:D6VU01|ensemblfungi:YGL148W	psi-mi:tnip1_human(display_long)|uniprotkb:TNIP1(gene name)|psi-mi:TNIP1(display_short)|uniprotkb:KIAA0113(gene name synonym)|uniprotkb:NAF1(gene name synonym)|uniprotkb:Nef-associated factor 1(gene name synonym)|uniprotkb:HIV-1 Nef-interacting protein(gene name synonym)|uniprotkb:Virion-associated nuclear shuttling protein(gene name synonym)|uniprotkb:Nip40-1(gene name synonym)|uniprotkb:A20-binding inhibitor of NF-kappa-B activation 1(gene name synonym)	psi-mi:aroc_yeast(display_long)|uniprotkb:ARO2(gene name)|psi-mi:ARO2(display_short)|uniprotkb:5-enolpyruvylshikimate-3-phosphate phospholyase(gene name synonym)|uniprotkb:YGL148W(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551556|imex:IM-24995-3460	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006049.3|refseq:NP_001239319.1|refseq:NP_001239320.1|refseq:NP_001239321.1|refseq:NP_001239322.1|refseq:NP_001245383.1|dip:DIP-27577N|refseq:NP_001239315.1|ensembl:ENSG00000145901(gene)|ensembl:ENST00000315050(transcript)|ensembl:ENST00000521591(transcript)|ensembl:ENST00000522226(transcript)|go:"GO:0002755"(MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0006952"(defense response)|go:"GO:0006954"(inflammatory response)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0009101"(glycoprotein biosynthetic process)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0085032"(modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade)|go:"GO:1903003"(positive regulation of protein deubiquitination)|interpro:IPR033372|mint:Q15025|reactome:R-HSA-5689896|go:"GO:0051019"(mitogen-activated protein kinase binding)|refseq:NP_001239314.1|refseq:NP_001245384.1|refseq:NP_001245385.1|refseq:XP_006714814.1|refseq:XP_006714815.1	refseq:NP_011367.1|sgd:S000003116|dip:DIP-4219N|ensemblfungi:YGL148W(gene)|ensemblfungi:YGL148W_mRNA(transcript)|go:"GO:0004107"(chorismate synthase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008652"(cellular amino acid biosynthetic process)|go:"GO:0009073"(aromatic amino acid family biosynthetic process)|go:"GO:0009423"(chorismate biosynthetic process)|go:"GO:0010181"(FMN binding)|go:"GO:0042602"("riboflavin reductase (NADPH) activity")|interpro:IPR000453(Chorismate synthase)|interpro:IPR020541|interpro:IPR035904|rcsb pdb:1R52|rcsb pdb:1R53	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:16Vjb5CuGTAbW2M22qbCxgXtV1o9606	rogid:JKW/ZDgiD3nPihuzkWGFypk8hlA559292	intact-crc:A54A7C28221AECD9|rigid:xb67E17xpRCwxPHLuS+ViVrLr2Y	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P29703	uniprotkb:Q15025	intact:EBI-14814|uniprotkb:D6VXR6|ensemblfungi:YKL019W	intact:EBI-357849|uniprotkb:A4F1W8|uniprotkb:O76008|uniprotkb:Q96EL9|uniprotkb:Q99833|uniprotkb:Q9H1J3|uniprotkb:B7Z699|uniprotkb:Q6N077|ensembl:ENSP00000317891|ensembl:ENSP00000428187|ensembl:ENSP00000430760|uniprotkb:A4F1W9|uniprotkb:A4F1X2|uniprotkb:A4F1X4|uniprotkb:A4F1X5|uniprotkb:A4F1X6|uniprotkb:A4F1X7|uniprotkb:A4F1X9|uniprotkb:E7EPY1|uniprotkb:E7ET96|uniprotkb:Q05KP3|uniprotkb:Q05KP4	psi-mi:fnta_yeast(display_long)|uniprotkb:YKL019W(locus name)|uniprotkb:RAM2(gene name)|psi-mi:RAM2(display_short)|uniprotkb:CAAX farnesyltransferase subunit alpha(gene name synonym)|uniprotkb:Ras proteins prenyltransferase subunit alpha(gene name synonym)|uniprotkb:FTase-alpha(gene name synonym)|uniprotkb:Type I protein geranyl-geranyltransferase subunit alpha(gene name synonym)	psi-mi:tnip1_human(display_long)|uniprotkb:TNIP1(gene name)|psi-mi:TNIP1(display_short)|uniprotkb:KIAA0113(gene name synonym)|uniprotkb:NAF1(gene name synonym)|uniprotkb:Nef-associated factor 1(gene name synonym)|uniprotkb:HIV-1 Nef-interacting protein(gene name synonym)|uniprotkb:Virion-associated nuclear shuttling protein(gene name synonym)|uniprotkb:Nip40-1(gene name synonym)|uniprotkb:A20-binding inhibitor of NF-kappa-B activation 1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551560|imex:IM-24995-3461	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000001502|refseq:NP_012906.3|go:"GO:0004662"(CAAX-protein geranylgeranyltransferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005953"(CAAX-protein geranylgeranyltransferase complex)|go:"GO:0005965"(protein farnesyltransferase complex)|go:"GO:0007323"(peptide pheromone maturation)|go:"GO:0018343"(protein farnesylation)|go:"GO:0018344"(protein geranylgeranylation)|interpro:IPR002088(Protein prenyltransferase, alpha subunit)|reactome:R-SCE-9648002|ensemblfungi:YKL019W(gene)|ensemblfungi:YKL019W_mRNA(transcript)|go:"GO:0004660"(protein farnesyltransferase activity)|go:"GO:0004661"(protein geranylgeranyltransferase activity)|dip:DIP-1233N|mint:P29703	refseq:NP_006049.3|refseq:NP_001239319.1|refseq:NP_001239320.1|refseq:NP_001239321.1|refseq:NP_001239322.1|refseq:NP_001245383.1|dip:DIP-27577N|refseq:NP_001239315.1|ensembl:ENSG00000145901(gene)|ensembl:ENST00000315050(transcript)|ensembl:ENST00000521591(transcript)|ensembl:ENST00000522226(transcript)|go:"GO:0002755"(MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0006952"(defense response)|go:"GO:0006954"(inflammatory response)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0009101"(glycoprotein biosynthetic process)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0085032"(modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade)|go:"GO:1903003"(positive regulation of protein deubiquitination)|interpro:IPR033372|mint:Q15025|reactome:R-HSA-5689896|go:"GO:0051019"(mitogen-activated protein kinase binding)|refseq:NP_001239314.1|refseq:NP_001245384.1|refseq:NP_001245385.1|refseq:XP_006714814.1|refseq:XP_006714815.1	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:u2rtpSuSW9Zd8LHWmniip7r5Ycs559292	rogid:16Vjb5CuGTAbW2M22qbCxgXtV1o9606	intact-crc:06DDBA0FA28878B4|rigid:sQJPT1NPCq43/Y+YRi9FtfmfISo	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P38340	uniprotkb:Q15025	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-357849|uniprotkb:A4F1W8|uniprotkb:O76008|uniprotkb:Q96EL9|uniprotkb:Q99833|uniprotkb:Q9H1J3|uniprotkb:B7Z699|uniprotkb:Q6N077|ensembl:ENSP00000317891|ensembl:ENSP00000428187|ensembl:ENSP00000430760|uniprotkb:A4F1W9|uniprotkb:A4F1X2|uniprotkb:A4F1X4|uniprotkb:A4F1X5|uniprotkb:A4F1X6|uniprotkb:A4F1X7|uniprotkb:A4F1X9|uniprotkb:E7EPY1|uniprotkb:E7ET96|uniprotkb:Q05KP3|uniprotkb:Q05KP4	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:tnip1_human(display_long)|uniprotkb:TNIP1(gene name)|psi-mi:TNIP1(display_short)|uniprotkb:KIAA0113(gene name synonym)|uniprotkb:NAF1(gene name synonym)|uniprotkb:Nef-associated factor 1(gene name synonym)|uniprotkb:HIV-1 Nef-interacting protein(gene name synonym)|uniprotkb:Virion-associated nuclear shuttling protein(gene name synonym)|uniprotkb:Nip40-1(gene name synonym)|uniprotkb:A20-binding inhibitor of NF-kappa-B activation 1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551576|imex:IM-24995-3465	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F	refseq:NP_006049.3|refseq:NP_001239319.1|refseq:NP_001239320.1|refseq:NP_001239321.1|refseq:NP_001239322.1|refseq:NP_001245383.1|dip:DIP-27577N|refseq:NP_001239315.1|ensembl:ENSG00000145901(gene)|ensembl:ENST00000315050(transcript)|ensembl:ENST00000521591(transcript)|ensembl:ENST00000522226(transcript)|go:"GO:0002755"(MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0006952"(defense response)|go:"GO:0006954"(inflammatory response)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0009101"(glycoprotein biosynthetic process)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0085032"(modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade)|go:"GO:1903003"(positive regulation of protein deubiquitination)|interpro:IPR033372|mint:Q15025|reactome:R-HSA-5689896|go:"GO:0051019"(mitogen-activated protein kinase binding)|refseq:NP_001239314.1|refseq:NP_001245384.1|refseq:NP_001245385.1|refseq:XP_006714814.1|refseq:XP_006714815.1	-	crc64:66699F37B0013088	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:16Vjb5CuGTAbW2M22qbCxgXtV1o9606	intact-crc:1B4CB41BF508740A|rigid:SBHyqjq5wE+LbLMQbXVnKqxweoo	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q15025	uniprotkb:P12945	intact:EBI-357849|uniprotkb:A4F1W8|uniprotkb:O76008|uniprotkb:Q96EL9|uniprotkb:Q99833|uniprotkb:Q9H1J3|uniprotkb:B7Z699|uniprotkb:Q6N077|ensembl:ENSP00000317891|ensembl:ENSP00000428187|ensembl:ENSP00000430760|uniprotkb:A4F1W9|uniprotkb:A4F1X2|uniprotkb:A4F1X4|uniprotkb:A4F1X5|uniprotkb:A4F1X6|uniprotkb:A4F1X7|uniprotkb:A4F1X9|uniprotkb:E7EPY1|uniprotkb:E7ET96|uniprotkb:Q05KP3|uniprotkb:Q05KP4	intact:EBI-11868|ensemblfungi:YDL040C|uniprotkb:D6VRV5	psi-mi:tnip1_human(display_long)|uniprotkb:TNIP1(gene name)|psi-mi:TNIP1(display_short)|uniprotkb:KIAA0113(gene name synonym)|uniprotkb:NAF1(gene name synonym)|uniprotkb:Nef-associated factor 1(gene name synonym)|uniprotkb:HIV-1 Nef-interacting protein(gene name synonym)|uniprotkb:Virion-associated nuclear shuttling protein(gene name synonym)|uniprotkb:Nip40-1(gene name synonym)|uniprotkb:A20-binding inhibitor of NF-kappa-B activation 1(gene name synonym)	psi-mi:nat1_yeast(display_long)|uniprotkb:NAT1(gene name)|psi-mi:NAT1(display_short)|uniprotkb:AAA1(gene name synonym)|uniprotkb:YDL040C(locus name)|uniprotkb:D2720(orf name)|uniprotkb:Amino-terminal, alpha-amino, acetyltransferase 1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551568|imex:IM-24995-3463	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006049.3|refseq:NP_001239319.1|refseq:NP_001239320.1|refseq:NP_001239321.1|refseq:NP_001239322.1|refseq:NP_001245383.1|dip:DIP-27577N|refseq:NP_001239315.1|ensembl:ENSG00000145901(gene)|ensembl:ENST00000315050(transcript)|ensembl:ENST00000521591(transcript)|ensembl:ENST00000522226(transcript)|go:"GO:0002755"(MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0006952"(defense response)|go:"GO:0006954"(inflammatory response)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0009101"(glycoprotein biosynthetic process)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0085032"(modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade)|go:"GO:1903003"(positive regulation of protein deubiquitination)|interpro:IPR033372|mint:Q15025|reactome:R-HSA-5689896|go:"GO:0051019"(mitogen-activated protein kinase binding)|refseq:NP_001239314.1|refseq:NP_001245384.1|refseq:NP_001245385.1|refseq:XP_006714814.1|refseq:XP_006714815.1	ensemblfungi:YDL040C(gene)|ensemblfungi:YDL040C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006474"(N-terminal protein amino acid acetylation)|go:"GO:0017196"(N-terminal peptidyl-methionine acetylation)|go:"GO:0031415"(NatA complex)|go:"GO:0043022"(ribosome binding)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR021183|rcsb pdb:4HNW|rcsb pdb:4HNY|rcsb pdb:4XNH|rcsb pdb:4XPD|rcsb pdb:4Y49|rcsb pdb:6HD5|rcsb pdb:6HD7|rcsb pdb:6O07|refseq:NP_010244.1|sgd:S000002198|dip:DIP-6329N|mint:P12945	-	-	crc64:DCFB870D049F91E6	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:16Vjb5CuGTAbW2M22qbCxgXtV1o9606	rogid:uzbL/wNoQ9nAcZzglVrbI4GKzOg559292	intact-crc:BE8A31BC2B73C181|rigid:nJkoXSkwLxk4qiNvOrjpzpV7Uos	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P40325	uniprotkb:Q15025	intact:EBI-23614|uniprotkb:D6VV46|ensemblfungi:YGR268C	intact:EBI-357849|uniprotkb:A4F1W8|uniprotkb:O76008|uniprotkb:Q96EL9|uniprotkb:Q99833|uniprotkb:Q9H1J3|uniprotkb:B7Z699|uniprotkb:Q6N077|ensembl:ENSP00000317891|ensembl:ENSP00000428187|ensembl:ENSP00000430760|uniprotkb:A4F1W9|uniprotkb:A4F1X2|uniprotkb:A4F1X4|uniprotkb:A4F1X5|uniprotkb:A4F1X6|uniprotkb:A4F1X7|uniprotkb:A4F1X9|uniprotkb:E7EPY1|uniprotkb:E7ET96|uniprotkb:Q05KP3|uniprotkb:Q05KP4	psi-mi:hua1_yeast(display_long)|uniprotkb:HUA1(gene name)|psi-mi:HUA1(display_short)|uniprotkb:YGR268C(locus name)	psi-mi:tnip1_human(display_long)|uniprotkb:TNIP1(gene name)|psi-mi:TNIP1(display_short)|uniprotkb:KIAA0113(gene name synonym)|uniprotkb:NAF1(gene name synonym)|uniprotkb:Nef-associated factor 1(gene name synonym)|uniprotkb:HIV-1 Nef-interacting protein(gene name synonym)|uniprotkb:Virion-associated nuclear shuttling protein(gene name synonym)|uniprotkb:Nip40-1(gene name synonym)|uniprotkb:A20-binding inhibitor of NF-kappa-B activation 1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551572|imex:IM-24995-3464	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003500|refseq:NP_011784.3|dip:DIP-1987N|ensemblfungi:YGR268C(gene)|ensemblfungi:YGR268C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|interpro:IPR038910	refseq:NP_006049.3|refseq:NP_001239319.1|refseq:NP_001239320.1|refseq:NP_001239321.1|refseq:NP_001239322.1|refseq:NP_001245383.1|dip:DIP-27577N|refseq:NP_001239315.1|ensembl:ENSG00000145901(gene)|ensembl:ENST00000315050(transcript)|ensembl:ENST00000521591(transcript)|ensembl:ENST00000522226(transcript)|go:"GO:0002755"(MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0006952"(defense response)|go:"GO:0006954"(inflammatory response)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0009101"(glycoprotein biosynthetic process)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0085032"(modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade)|go:"GO:1903003"(positive regulation of protein deubiquitination)|interpro:IPR033372|mint:Q15025|reactome:R-HSA-5689896|go:"GO:0051019"(mitogen-activated protein kinase binding)|refseq:NP_001239314.1|refseq:NP_001245384.1|refseq:NP_001245385.1|refseq:XP_006714814.1|refseq:XP_006714815.1	-	crc64:78029FD484168793	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:xliNG9XUWbYRd0Nbu+xzCgxNrAs559292	rogid:16Vjb5CuGTAbW2M22qbCxgXtV1o9606	intact-crc:8533AB17887B2261|rigid:yPFZ0WNJj6iZqkuwZFycMhRekpE	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q02821	uniprotkb:Q15038	intact:EBI-1797|uniprotkb:D6W0Z8|ensemblfungi:YNL189W	intact:EBI-724310|ensembl:ENSP00000394699|uniprotkb:E9PB45|uniprotkb:A8K254|uniprotkb:B4DDT5|uniprotkb:C9JA96|uniprotkb:C9JP84|uniprotkb:B4E1G3|uniprotkb:F8VU62	psi-mi:ima1_yeast(display_long)|uniprotkb:SRP1(gene name)|psi-mi:SRP1(display_short)|uniprotkb:KAP60(gene name synonym)|uniprotkb:YNL189W(locus name)|uniprotkb:N1606(orf name)|uniprotkb:Karyopherin subunit alpha(gene name synonym)|uniprotkb:Karyopherin-60(gene name synonym)|uniprotkb:Serine-rich RNA polymerase I suppressor protein(gene name synonym)	psi-mi:dazp2_human(display_long)|uniprotkb:Deleted in azoospermia-associated protein 2(gene name synonym)|uniprotkb:DAZAP2(gene name)|psi-mi:DAZAP2(display_short)|uniprotkb:KIAA0058(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551592|imex:IM-24995-3469	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014210.1|sgd:S000005133|dip:DIP-728N|mint:Q02821|ensemblfungi:YNL189W(gene)|ensemblfungi:YNL189W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0031144"(proteasome localization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042564"(NLS-dependent protein nuclear import complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|rcsb pdb:1BK5|rcsb pdb:1BK6|rcsb pdb:1EE4|rcsb pdb:1EE5|rcsb pdb:1UN0|rcsb pdb:1WA5|rcsb pdb:2C1T|rcsb pdb:4PVZ|rcsb pdb:4XZR|rcsb pdb:5H2W|rcsb pdb:5H2X|rcsb pdb:5T94	ensembl:ENSG00000183283(gene)|ensembl:ENST00000412716(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0016607"(nuclear speck)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0050699"(WW domain binding)|interpro:IPR022730|mint:Q15038|refseq:NP_001129736.1|refseq:NP_055579.1|ensembl:ENSP00000394699|ensembl:ENST00000425012|ensembl:ENSP00000408251|ensembl:ENST00000439799|ensembl:ENSP00000398804|ensembl:ENST00000449723|ensembl:ENSP00000412812|ensembl:ENST00000549555|ensembl:ENSP00000448051|ensembl:ENST00000549732|ensembl:ENSP00000446554|refseq:NP_001129741.1|refseq:NP_001129739.1|refseq:NP_001129740.1|refseq:NP_001129738.1	-	crc64:8D3A0CB76F2E7C00	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:NyzC93xnBCb8DX/AH346lwg4u2A559292	rogid:ASRqCZBG4q1U/y95PUSMKsgfm/g9606	intact-crc:FC268F3C88292770|rigid:yCLVefhV7x77d29dFaxQHSx62kQ	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q15025	uniprotkb:P32571	intact:EBI-357849|uniprotkb:A4F1W8|uniprotkb:O76008|uniprotkb:Q96EL9|uniprotkb:Q99833|uniprotkb:Q9H1J3|uniprotkb:B7Z699|uniprotkb:Q6N077|ensembl:ENSP00000317891|ensembl:ENSP00000428187|ensembl:ENSP00000430760|uniprotkb:A4F1W9|uniprotkb:A4F1X2|uniprotkb:A4F1X4|uniprotkb:A4F1X5|uniprotkb:A4F1X6|uniprotkb:A4F1X7|uniprotkb:A4F1X9|uniprotkb:E7EPY1|uniprotkb:E7ET96|uniprotkb:Q05KP3|uniprotkb:Q05KP4	intact:EBI-19840|uniprotkb:D6VS55|ensemblfungi:YDR069C	psi-mi:tnip1_human(display_long)|uniprotkb:TNIP1(gene name)|psi-mi:TNIP1(display_short)|uniprotkb:KIAA0113(gene name synonym)|uniprotkb:NAF1(gene name synonym)|uniprotkb:Nef-associated factor 1(gene name synonym)|uniprotkb:HIV-1 Nef-interacting protein(gene name synonym)|uniprotkb:Virion-associated nuclear shuttling protein(gene name synonym)|uniprotkb:Nip40-1(gene name synonym)|uniprotkb:A20-binding inhibitor of NF-kappa-B activation 1(gene name synonym)	psi-mi:ubp4_yeast(display_long)|uniprotkb:DOA4(gene name)|psi-mi:DOA4(display_short)|uniprotkb:MUT4(gene name synonym)|uniprotkb:SSV7(gene name synonym)|uniprotkb:YDR069C(locus name)|uniprotkb:YD9609.23C(orf name)|uniprotkb:YD8554.02C(orf name)|uniprotkb:D4270(orf name)|uniprotkb:NPI2(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 4(gene name synonym)|uniprotkb:Deubiquitinating enzyme 4(gene name synonym)|uniprotkb:Vacuole biogenesis protein SSV7(gene name synonym)|uniprotkb:Ubiquitin thioesterase 4(gene name synonym)|uniprotkb:DOS1(gene name synonym)|uniprotkb:UBP4(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551580|imex:IM-24995-3466	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006049.3|refseq:NP_001239319.1|refseq:NP_001239320.1|refseq:NP_001239321.1|refseq:NP_001239322.1|refseq:NP_001245383.1|dip:DIP-27577N|refseq:NP_001239315.1|ensembl:ENSG00000145901(gene)|ensembl:ENST00000315050(transcript)|ensembl:ENST00000521591(transcript)|ensembl:ENST00000522226(transcript)|go:"GO:0002755"(MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0006952"(defense response)|go:"GO:0006954"(inflammatory response)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0009101"(glycoprotein biosynthetic process)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0085032"(modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade)|go:"GO:1903003"(positive regulation of protein deubiquitination)|interpro:IPR033372|mint:Q15025|reactome:R-HSA-5689896|go:"GO:0051019"(mitogen-activated protein kinase binding)|refseq:NP_001239314.1|refseq:NP_001245384.1|refseq:NP_001245385.1|refseq:XP_006714814.1|refseq:XP_006714815.1	sgd:S000002476|ensemblfungi:YDR069C(gene)|ensemblfungi:YDR069C_mRNA(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005739"(mitochondrion)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0010992"(ubiquitin recycling)|go:"GO:0010995"(free ubiquitin chain depolymerization)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0031902"(late endosome membrane)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0070676"(intralumenal vesicle formation)|go:"GO:1904669"(ATP export)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR001763(Rhodanese-like)|interpro:IPR018200|interpro:IPR028889|interpro:IPR036873|interpro:IPR038765|refseq:NP_010354.3|dip:DIP-5298N|mint:P32571	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:16Vjb5CuGTAbW2M22qbCxgXtV1o9606	rogid:UTBSWmpygyxo1ygxp/sQ8wgqnMo559292	intact-crc:0A9FE66D9403418E|rigid:ijitWknNv+h+mXOvzIRz19XPe8A	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P40956	uniprotkb:Q15038	intact:EBI-7968|uniprotkb:D6VTX2|ensemblfungi:YGL181W	intact:EBI-724310|ensembl:ENSP00000394699|uniprotkb:E9PB45|uniprotkb:A8K254|uniprotkb:B4DDT5|uniprotkb:C9JA96|uniprotkb:C9JP84|uniprotkb:B4E1G3|uniprotkb:F8VU62	psi-mi:gts1_yeast(display_long)|uniprotkb:YGL181W(locus name)|uniprotkb:GTS1(gene name)|psi-mi:GTS1(display_short)|uniprotkb:LSR1(gene name synonym)|uniprotkb:Protein LSR1(gene name synonym)	psi-mi:dazp2_human(display_long)|uniprotkb:Deleted in azoospermia-associated protein 2(gene name synonym)|uniprotkb:DAZAP2(gene name)|psi-mi:DAZAP2(display_short)|uniprotkb:KIAA0058(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551584|imex:IM-24995-3467	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011334.1|sgd:S000003149|mint:P40956|dip:DIP-2746N|ensemblfungi:YGL181W(gene)|ensemblfungi:YGL181W_mRNA(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0006897"(endocytosis)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010512"(negative regulation of phosphatidylinositol biosynthetic process)|go:"GO:0030479"(actin cortical patch)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR037278|interpro:IPR038508	ensembl:ENSG00000183283(gene)|ensembl:ENST00000412716(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0016607"(nuclear speck)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0050699"(WW domain binding)|interpro:IPR022730|mint:Q15038|refseq:NP_001129736.1|refseq:NP_055579.1|ensembl:ENSP00000394699|ensembl:ENST00000425012|ensembl:ENSP00000408251|ensembl:ENST00000439799|ensembl:ENSP00000398804|ensembl:ENST00000449723|ensembl:ENSP00000412812|ensembl:ENST00000549555|ensembl:ENSP00000448051|ensembl:ENST00000549732|ensembl:ENSP00000446554|refseq:NP_001129741.1|refseq:NP_001129739.1|refseq:NP_001129740.1|refseq:NP_001129738.1	-	crc64:D687E3BF6B620795	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:8kgpssCRrHiTHsFaOH2nDK6EIjk559292	rogid:ASRqCZBG4q1U/y95PUSMKsgfm/g9606	intact-crc:2029B4C7298040EF|rigid:tq/jX7xeiamy1eGRo5l6cuOWtgU	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q15038	uniprotkb:P54787	intact:EBI-724310|ensembl:ENSP00000394699|uniprotkb:E9PB45|uniprotkb:A8K254|uniprotkb:B4DDT5|uniprotkb:C9JA96|uniprotkb:C9JP84|uniprotkb:B4E1G3|uniprotkb:F8VU62	intact:EBI-20495|uniprotkb:D6W0I8|ensemblfungi:YML097C	psi-mi:dazp2_human(display_long)|uniprotkb:Deleted in azoospermia-associated protein 2(gene name synonym)|uniprotkb:DAZAP2(gene name)|psi-mi:DAZAP2(display_short)|uniprotkb:KIAA0058(gene name synonym)	psi-mi:vps9_yeast(display_long)|uniprotkb:VPS9(gene name)|psi-mi:VPS9(display_short)|uniprotkb:Vacuolar protein-targeting protein 9(gene name synonym)|uniprotkb:VPT9(gene name synonym)|uniprotkb:YML097C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551588|imex:IM-24995-3468	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000183283(gene)|ensembl:ENST00000412716(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0016607"(nuclear speck)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0050699"(WW domain binding)|interpro:IPR022730|mint:Q15038|refseq:NP_001129736.1|refseq:NP_055579.1|ensembl:ENSP00000394699|ensembl:ENST00000425012|ensembl:ENSP00000408251|ensembl:ENST00000439799|ensembl:ENSP00000398804|ensembl:ENST00000449723|ensembl:ENSP00000412812|ensembl:ENST00000549555|ensembl:ENSP00000448051|ensembl:ENST00000549732|ensembl:ENSP00000446554|refseq:NP_001129741.1|refseq:NP_001129739.1|refseq:NP_001129740.1|refseq:NP_001129738.1	refseq:NP_013612.1|sgd:S000004563|ensemblfungi:YML097C(gene)|ensemblfungi:YML097C_mRNA(transcript)|go:"GO:0000011"(vacuole inheritance)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR009060(UBA-like)|interpro:IPR037191|interpro:IPR041545|interpro:IPR041804|rcsb pdb:1MN3|rcsb pdb:1P3Q|reactome:R-SCE-8876198|reactome:R-SCE-8856828|dip:DIP-4526N|mint:P54787	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:ASRqCZBG4q1U/y95PUSMKsgfm/g9606	rogid:ogXRiOOp698mlPdAiFidYakMtI4559292	intact-crc:18BE70CA8A40005E|rigid:DwpVDWgt7l//tipQ+xSc9Jye/M8	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P39518	uniprotkb:Q15041	intact:EBI-10082|uniprotkb:D3DLR3|ensemblfungi:YER015W	intact:EBI-714543|ensembl:ENSP00000306788|uniprotkb:B7Z6S5|uniprotkb:B7Z791|uniprotkb:F5GXP4	psi-mi:lcf2_yeast(display_long)|uniprotkb:YER015W(locus name)|uniprotkb:FAA2(gene name)|psi-mi:FAA2(display_short)|uniprotkb:FAM1(gene name synonym)|uniprotkb:Long-chain acyl-CoA synthetase 2(gene name synonym)|uniprotkb:Fatty acid activator 2(gene name synonym)	psi-mi:ar6p1_human(display_long)|uniprotkb:ARL6IP(gene name synonym)|uniprotkb:ARL6IP1(gene name)|psi-mi:ARL6IP1(display_short)|uniprotkb:KIAA0069(gene name synonym)|uniprotkb:ARMER(gene name synonym)|uniprotkb:Apoptotic regulator in the membrane of the endoplasmic reticulum(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551612|imex:IM-24995-3474	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000000817|ensemblfungi:YER015W_mRNA(transcript)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0004467"(long-chain fatty acid-CoA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0015910"(long-chain fatty acid import into peroxisome)|go:"GO:0015916"(fatty-acyl-CoA transport)|go:"GO:0016020"(membrane)|go:"GO:0031956"(medium-chain fatty acid-CoA ligase activity)|go:"GO:0031957"(very long-chain fatty acid-CoA ligase activity)|go:"GO:0042760"(very long-chain fatty acid catabolic process)|go:"GO:0102391"(decanoate-CoA ligase activity)|ensemblfungi:YER015W(gene)|interpro:IPR020845|interpro:IPR000873(AMP-dependent synthetase and ligase)|reactome:R-SCE-75876|refseq:NP_010931.3|dip:DIP-6565N	refseq:NP_055976.1|ensembl:ENSG00000170540(gene)|ensembl:ENST00000304414(transcript)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006613"(cotranslational protein targeting to membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0071787"(endoplasmic reticulum tubular network formation)|go:"GO:1903371"(regulation of endoplasmic reticulum tubular network organization)|go:"GO:1990809"(endoplasmic reticulum tubular network membrane organization)|interpro:IPR033301|mint:Q15041|go:"GO:0002038"(positive regulation of L-glutamate import across plasma membrane)|refseq:NP_001300787.1	-	crc64:1E023C18682805BC	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:N0W+wPvCsl01y0k8hJZ156LztOo559292	rogid:3fjkoyvUx25po7xsPcXgpjEeLJg9606	intact-crc:63795F0170FA589E|rigid:ov9rVkwnhLHkf4vKK1snMQdp5sY	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q02724	uniprotkb:Q15041	intact:EBI-20050|uniprotkb:D6W3Z2|ensemblfungi:YPL020C	intact:EBI-714543|ensembl:ENSP00000306788|uniprotkb:B7Z6S5|uniprotkb:B7Z791|uniprotkb:F5GXP4	psi-mi:ulp1_yeast(display_long)|uniprotkb:ULP1(gene name)|psi-mi:ULP1(display_short)|uniprotkb:LPB11C(orf name)|uniprotkb:YPL020C(locus name)	psi-mi:ar6p1_human(display_long)|uniprotkb:ARL6IP(gene name synonym)|uniprotkb:ARL6IP1(gene name)|psi-mi:ARL6IP1(display_short)|uniprotkb:KIAA0069(gene name synonym)|uniprotkb:ARMER(gene name synonym)|uniprotkb:Apoptotic regulator in the membrane of the endoplasmic reticulum(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551608|imex:IM-24995-3473	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015305.1|sgd:S000005941|ensemblfungi:YPL020C(gene)|ensemblfungi:YPL020C_mRNA(transcript)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005730"(nucleolus)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0016926"(protein desumoylation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070140"(SUMO-specific isopeptidase activity)|interpro:IPR003653(Peptidase C48, SUMO/Sentrin/Ubl1)|interpro:IPR038765|rcsb pdb:1EUV|rcsb pdb:2HKP|rcsb pdb:2HL8|rcsb pdb:2HL9|rcsb pdb:5H2V|rcsb pdb:5H2W|rcsb pdb:5H2X|reactome:R-SCE-3065679|reactome:R-SCE-6791226|dip:DIP-4041N|mint:Q02724	refseq:NP_055976.1|ensembl:ENSG00000170540(gene)|ensembl:ENST00000304414(transcript)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006613"(cotranslational protein targeting to membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0071787"(endoplasmic reticulum tubular network formation)|go:"GO:1903371"(regulation of endoplasmic reticulum tubular network organization)|go:"GO:1990809"(endoplasmic reticulum tubular network membrane organization)|interpro:IPR033301|mint:Q15041|go:"GO:0002038"(positive regulation of L-glutamate import across plasma membrane)|refseq:NP_001300787.1	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:H9B4qZf/ZMbHr7u4hbtR4fzz0ec559292	rogid:3fjkoyvUx25po7xsPcXgpjEeLJg9606	intact-crc:E458CFC2E8F614EF|rigid:RIbaQ21M7h0vj230QEBaFTZm9ok	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P47162	uniprotkb:Q15038	intact:EBI-11532550|uniprotkb:A0A1S0T089|ensemblfungi:YJR128W	intact:EBI-724310|ensembl:ENSP00000394699|uniprotkb:E9PB45|uniprotkb:A8K254|uniprotkb:B4DDT5|uniprotkb:C9JA96|uniprotkb:C9JP84|uniprotkb:B4E1G3|uniprotkb:F8VU62	psi-mi:yj98_yeast(display_long)|uniprotkb:J2059(orf name)|uniprotkb:YJR128W(locus name)	psi-mi:dazp2_human(display_long)|uniprotkb:Deleted in azoospermia-associated protein 2(gene name synonym)|uniprotkb:DAZAP2(gene name)|psi-mi:DAZAP2(display_short)|uniprotkb:KIAA0058(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551596|imex:IM-24995-3470	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003889|ensemblfungi:YJR128W(gene)|ensemblfungi:YJR128W_mRNA(transcript)	ensembl:ENSG00000183283(gene)|ensembl:ENST00000412716(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0016607"(nuclear speck)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0050699"(WW domain binding)|interpro:IPR022730|mint:Q15038|refseq:NP_001129736.1|refseq:NP_055579.1|ensembl:ENSP00000394699|ensembl:ENST00000425012|ensembl:ENSP00000408251|ensembl:ENST00000439799|ensembl:ENSP00000398804|ensembl:ENST00000449723|ensembl:ENSP00000412812|ensembl:ENST00000549555|ensembl:ENSP00000448051|ensembl:ENST00000549732|ensembl:ENSP00000446554|refseq:NP_001129741.1|refseq:NP_001129739.1|refseq:NP_001129740.1|refseq:NP_001129738.1	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/03/16	rogid:utEI06SlO/HvqiPnUtJUHtxxOBo559292	rogid:ASRqCZBG4q1U/y95PUSMKsgfm/g9606	intact-crc:C9DDA0509B35EE4C|rigid:wfMFpeoVlRmYhu/ezZM1vkzm8ek	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q15038	uniprotkb:P38340	intact:EBI-724310|ensembl:ENSP00000394699|uniprotkb:E9PB45|uniprotkb:A8K254|uniprotkb:B4DDT5|uniprotkb:C9JA96|uniprotkb:C9JP84|uniprotkb:B4E1G3|uniprotkb:F8VU62	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:dazp2_human(display_long)|uniprotkb:Deleted in azoospermia-associated protein 2(gene name synonym)|uniprotkb:DAZAP2(gene name)|psi-mi:DAZAP2(display_short)|uniprotkb:KIAA0058(gene name synonym)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551600|imex:IM-24995-3471	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000183283(gene)|ensembl:ENST00000412716(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0016607"(nuclear speck)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0050699"(WW domain binding)|interpro:IPR022730|mint:Q15038|refseq:NP_001129736.1|refseq:NP_055579.1|ensembl:ENSP00000394699|ensembl:ENST00000425012|ensembl:ENSP00000408251|ensembl:ENST00000439799|ensembl:ENSP00000398804|ensembl:ENST00000449723|ensembl:ENSP00000412812|ensembl:ENST00000549555|ensembl:ENSP00000448051|ensembl:ENST00000549732|ensembl:ENSP00000446554|refseq:NP_001129741.1|refseq:NP_001129739.1|refseq:NP_001129740.1|refseq:NP_001129738.1	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F	-	-	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:ASRqCZBG4q1U/y95PUSMKsgfm/g9606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:C6E4465A98D029FD|rigid:tWYfZtkHuwaAtyHJIKpEo2Z9YTY	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q15038	uniprotkb:P0CH08	intact:EBI-724310|ensembl:ENSP00000394699|uniprotkb:E9PB45|uniprotkb:A8K254|uniprotkb:B4DDT5|uniprotkb:C9JA96|uniprotkb:C9JP84|uniprotkb:B4E1G3|uniprotkb:F8VU62	intact:EBI-11523108|uniprotkb:D6VVD9|uniprotkb:P04838|uniprotkb:P14796|uniprotkb:P61864|uniprotkb:Q6LA96|ensemblfungi:YIL148W|ensemblfungi:YKR094C	psi-mi:dazp2_human(display_long)|uniprotkb:Deleted in azoospermia-associated protein 2(gene name synonym)|uniprotkb:DAZAP2(gene name)|psi-mi:DAZAP2(display_short)|uniprotkb:KIAA0058(gene name synonym)	psi-mi:rl40a_yeast(display_long)|uniprotkb:RPL40A(gene name)|psi-mi:RPL40A(display_short)|uniprotkb:UBI1(gene name synonym)|uniprotkb:YIL148W(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551604|imex:IM-24995-3472	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000183283(gene)|ensembl:ENST00000412716(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0016607"(nuclear speck)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0050699"(WW domain binding)|interpro:IPR022730|mint:Q15038|refseq:NP_001129736.1|refseq:NP_055579.1|ensembl:ENSP00000394699|ensembl:ENST00000425012|ensembl:ENSP00000408251|ensembl:ENST00000439799|ensembl:ENSP00000398804|ensembl:ENST00000449723|ensembl:ENSP00000412812|ensembl:ENST00000549555|ensembl:ENSP00000448051|ensembl:ENST00000549732|ensembl:ENSP00000446554|refseq:NP_001129741.1|refseq:NP_001129739.1|refseq:NP_001129740.1|refseq:NP_001129738.1	rcsb pdb:5NDG|rcsb pdb:5NDV|rcsb pdb:5NDW|rcsb pdb:5OBM|rcsb pdb:6WOO|interpro:IPR000626(Ubiquitin)|interpro:IPR001975(Ribosomal protein L40e)|interpro:IPR019954|interpro:IPR019956|interpro:IPR029071|rcsb pdb:3J6X|rcsb pdb:3J6Y|rcsb pdb:3J77|rcsb pdb:3J78|rcsb pdb:4U3M|rcsb pdb:4U3N|rcsb pdb:4U3U|rcsb pdb:4U4N|rcsb pdb:4U4O|rcsb pdb:4U4Q|rcsb pdb:4U4R|rcsb pdb:4U4U|rcsb pdb:4U4Y|rcsb pdb:4U4Z|rcsb pdb:4U50|rcsb pdb:4U51|rcsb pdb:4U52|rcsb pdb:4U53|rcsb pdb:4U55|rcsb pdb:4U56|rcsb pdb:4U6F|rcsb pdb:4V6I|rcsb pdb:4V88|rcsb pdb:4V8T|rcsb pdb:4V8Y|rcsb pdb:4V8Z|rcsb pdb:5APN|rcsb pdb:5APO|refseq:NP_012118.1|refseq:NP_013020.3|sgd:S000001410|rcsb pdb:6TB3|rcsb pdb:6TNU|rcsb pdb:5DGE|rcsb pdb:5M1J|rcsb pdb:5MC6|rcsb pdb:5TGM|rcsb pdb:6EF3|rcsb pdb:6OIG|rcsb pdb:6OA9|rcsb pdb:6OAA|rcsb pdb:6QIK|rcsb pdb:6QT0|rcsb pdb:6QTZ|rcsb pdb:6R84|rcsb pdb:6R87|rcsb pdb:6RI5|rcsb pdb:5FCI|rcsb pdb:5FCJ|rcsb pdb:5DGF|rcsb pdb:5DGV|rcsb pdb:5LYB|rcsb pdb:5TGA|rcsb pdb:6HHQ|rcsb pdb:5DC3|rcsb pdb:5I4L|rcsb pdb:6N8M|rcsb pdb:6N8N|rcsb pdb:6N8O|rcsb pdb:6I7O|rcsb pdb:7AZY|rcsb pdb:7B7D|rcsb pdb:7NRC|rcsb pdb:7NRD|reactome:R-SCE-1169408|reactome:R-SCE-5656169|rcsb pdb:5GAK|rcsb pdb:6Q8Y|ensemblfungi:YIL148W(gene)|ensemblfungi:YIL148W_mRNA(transcript)|ensemblfungi:YKR094C(gene)|ensemblfungi:YKR094C_mRNA(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0031386"(protein tag)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042254"(ribosome biogenesis)|rcsb pdb:6HD7|rcsb pdb:5ON6|rcsb pdb:5DAT|rcsb pdb:5JUO|rcsb pdb:5JUP|rcsb pdb:5JUS|rcsb pdb:5JUT|rcsb pdb:5JUU|rcsb pdb:5T62|rcsb pdb:5T6R|interpro:IPR038587|rcsb pdb:5MEI|rcsb pdb:5TBW|rcsb pdb:6GQ1|rcsb pdb:6GQB|rcsb pdb:6GQV|rcsb pdb:6R86|rcsb pdb:6S47|rcsb pdb:6NYO|rcsb pdb:6T4Q|rcsb pdb:6T7I|rcsb pdb:6T7T|rcsb pdb:6T83|rcsb pdb:6SNT|rcsb pdb:6SV4|rcsb pdb:6XIQ|rcsb pdb:6Z6J|rcsb pdb:6Z6K	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/03/16	rogid:ASRqCZBG4q1U/y95PUSMKsgfm/g9606	rogid:6+5uVAktIpS9HyPHQ6BzXEuT/y0559292	intact-crc:A59A0B8F5467275D|rigid:Lh/mIxvSJnpc6qjoQ5u0j8lqgrA	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P32453	uniprotkb:Q15041	intact:EBI-3306|uniprotkb:D6W0N0|ensemblfungi:YNL315C	intact:EBI-714543|ensembl:ENSP00000306788|uniprotkb:B7Z6S5|uniprotkb:B7Z791|uniprotkb:F5GXP4	psi-mi:atp11_yeast(display_long)|uniprotkb:ATP11(gene name)|psi-mi:ATP11(display_short)|uniprotkb:N0357(orf name)|uniprotkb:YNL315C(locus name)	psi-mi:ar6p1_human(display_long)|uniprotkb:ARL6IP(gene name synonym)|uniprotkb:ARL6IP1(gene name)|psi-mi:ARL6IP1(display_short)|uniprotkb:KIAA0069(gene name synonym)|uniprotkb:ARMER(gene name synonym)|uniprotkb:Apoptotic regulator in the membrane of the endoplasmic reticulum(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551628|imex:IM-24995-3478	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014084.1|sgd:S000005259|dip:DIP-3026N|mint:P32453|ensemblfungi:YNL315C(gene)|ensemblfungi:YNL315C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0033615"(mitochondrial proton-transporting ATP synthase complex assembly)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR010591(ATP11)	refseq:NP_055976.1|ensembl:ENSG00000170540(gene)|ensembl:ENST00000304414(transcript)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006613"(cotranslational protein targeting to membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0071787"(endoplasmic reticulum tubular network formation)|go:"GO:1903371"(regulation of endoplasmic reticulum tubular network organization)|go:"GO:1990809"(endoplasmic reticulum tubular network membrane organization)|interpro:IPR033301|mint:Q15041|go:"GO:0002038"(positive regulation of L-glutamate import across plasma membrane)|refseq:NP_001300787.1	-	crc64:61109AA4D338F2CD	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:JsQu6HtKtGqAVhHzaPVc8IMYdqM559292	rogid:3fjkoyvUx25po7xsPcXgpjEeLJg9606	intact-crc:F1BD62B42261209E|rigid:yyzxtYV9KcvFNA2QogAC0WqTvFY	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q02821	uniprotkb:Q15041	intact:EBI-1797|uniprotkb:D6W0Z8|ensemblfungi:YNL189W	intact:EBI-714543|ensembl:ENSP00000306788|uniprotkb:B7Z6S5|uniprotkb:B7Z791|uniprotkb:F5GXP4	psi-mi:ima1_yeast(display_long)|uniprotkb:SRP1(gene name)|psi-mi:SRP1(display_short)|uniprotkb:KAP60(gene name synonym)|uniprotkb:YNL189W(locus name)|uniprotkb:N1606(orf name)|uniprotkb:Karyopherin subunit alpha(gene name synonym)|uniprotkb:Karyopherin-60(gene name synonym)|uniprotkb:Serine-rich RNA polymerase I suppressor protein(gene name synonym)	psi-mi:ar6p1_human(display_long)|uniprotkb:ARL6IP(gene name synonym)|uniprotkb:ARL6IP1(gene name)|psi-mi:ARL6IP1(display_short)|uniprotkb:KIAA0069(gene name synonym)|uniprotkb:ARMER(gene name synonym)|uniprotkb:Apoptotic regulator in the membrane of the endoplasmic reticulum(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551616|imex:IM-24995-3475	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014210.1|sgd:S000005133|dip:DIP-728N|mint:Q02821|ensemblfungi:YNL189W(gene)|ensemblfungi:YNL189W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0031144"(proteasome localization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042564"(NLS-dependent protein nuclear import complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|rcsb pdb:1BK5|rcsb pdb:1BK6|rcsb pdb:1EE4|rcsb pdb:1EE5|rcsb pdb:1UN0|rcsb pdb:1WA5|rcsb pdb:2C1T|rcsb pdb:4PVZ|rcsb pdb:4XZR|rcsb pdb:5H2W|rcsb pdb:5H2X|rcsb pdb:5T94	refseq:NP_055976.1|ensembl:ENSG00000170540(gene)|ensembl:ENST00000304414(transcript)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006613"(cotranslational protein targeting to membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0071787"(endoplasmic reticulum tubular network formation)|go:"GO:1903371"(regulation of endoplasmic reticulum tubular network organization)|go:"GO:1990809"(endoplasmic reticulum tubular network membrane organization)|interpro:IPR033301|mint:Q15041|go:"GO:0002038"(positive regulation of L-glutamate import across plasma membrane)|refseq:NP_001300787.1	-	crc64:8D3A0CB76F2E7C00	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:NyzC93xnBCb8DX/AH346lwg4u2A559292	rogid:3fjkoyvUx25po7xsPcXgpjEeLJg9606	intact-crc:6D9F432BCA780FBC|rigid:IgRYyzm7Dnd+YxZ8YMSEE+zMZNs	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P12612	uniprotkb:Q15041	intact:EBI-19045|uniprotkb:D6VSJ6|ensemblfungi:YDR212W	intact:EBI-714543|ensembl:ENSP00000306788|uniprotkb:B7Z6S5|uniprotkb:B7Z791|uniprotkb:F5GXP4	psi-mi:tcpa_yeast(display_long)|uniprotkb:TCP1(gene name)|psi-mi:TCP1(display_short)|uniprotkb:CCT1(gene name synonym)|uniprotkb:YDR212W(locus name)|uniprotkb:YD8142.13(orf name)|uniprotkb:YD8142B.04(orf name)|uniprotkb:CCT-alpha(gene name synonym)	psi-mi:ar6p1_human(display_long)|uniprotkb:ARL6IP(gene name synonym)|uniprotkb:ARL6IP1(gene name)|psi-mi:ARL6IP1(display_short)|uniprotkb:KIAA0069(gene name synonym)|uniprotkb:ARMER(gene name synonym)|uniprotkb:Apoptotic regulator in the membrane of the endoplasmic reticulum(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551620|imex:IM-24995-3476	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010498.1|sgd:S000002620|ensemblfungi:YDR212W(gene)|ensemblfungi:YDR212W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012715(T-complex protein 1, alpha subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|rcsb pdb:4V81|rcsb pdb:4V8R|rcsb pdb:4V94|rcsb pdb:5GW4|rcsb pdb:5GW5|rcsb pdb:6KRD|rcsb pdb:6KRE|rcsb pdb:6KS6|rcsb pdb:6KS7|rcsb pdb:6KS8|reactome:R-SCE-390471|reactome:R-SCE-6814122|dip:DIP-2965N|mint:P12612	refseq:NP_055976.1|ensembl:ENSG00000170540(gene)|ensembl:ENST00000304414(transcript)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006613"(cotranslational protein targeting to membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0071787"(endoplasmic reticulum tubular network formation)|go:"GO:1903371"(regulation of endoplasmic reticulum tubular network organization)|go:"GO:1990809"(endoplasmic reticulum tubular network membrane organization)|interpro:IPR033301|mint:Q15041|go:"GO:0002038"(positive regulation of L-glutamate import across plasma membrane)|refseq:NP_001300787.1	-	crc64:02C625D329359E61	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:xWMsvY106Y6yQ54SOif2UlScafM559292	rogid:3fjkoyvUx25po7xsPcXgpjEeLJg9606	intact-crc:17DB1F36A8098751|rigid:hg9kriFmHA5VRfK4C/zEWeN7Jeg	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P04819	uniprotkb:Q15041	intact:EBI-5991|uniprotkb:Q12736|uniprotkb:D6VRI7|ensemblfungi:YDL164C	intact:EBI-714543|ensembl:ENSP00000306788|uniprotkb:B7Z6S5|uniprotkb:B7Z791|uniprotkb:F5GXP4	psi-mi:dnli1_yeast(display_long)|uniprotkb:YDL164C(locus name)|uniprotkb:CDC9(gene name)|psi-mi:CDC9(display_short)|uniprotkb:DNA ligase I(gene name synonym)|uniprotkb:Polydeoxyribonucleotide synthase [ATP] 1(gene name synonym)	psi-mi:ar6p1_human(display_long)|uniprotkb:ARL6IP(gene name synonym)|uniprotkb:ARL6IP1(gene name)|psi-mi:ARL6IP1(display_short)|uniprotkb:KIAA0069(gene name synonym)|uniprotkb:ARMER(gene name synonym)|uniprotkb:Apoptotic regulator in the membrane of the endoplasmic reticulum(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551624|imex:IM-24995-3477	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010117.1|sgd:S000002323|dip:DIP-5630N|mint:P04819|ensemblfungi:YDL164C(gene)|ensemblfungi:YDL164C_mRNA(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003677"(DNA binding)|go:"GO:0003910"("DNA ligase (ATP) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006266"(DNA ligation)|go:"GO:0006273"(lagging strand elongation)|go:"GO:0006284"(base-excision repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0035753"(maintenance of DNA trinucleotide repeats)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:0071897"(DNA biosynthetic process)|go:"GO:1903461"(Okazaki fragment processing involved in mitotic DNA replication)|interpro:IPR000977(ATP-dependent DNA ligase)|interpro:IPR012308(DNA ligase, N-terminal)|interpro:IPR012309(ATP dependent DNA ligase, C-terminal)|interpro:IPR012310(ATP dependent DNA ligase, central)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR016059(ATP-dependent DNA ligase, conserved site)|interpro:IPR036599|rcsb pdb:2OD8|reactome:R-SCE-5358565|reactome:R-SCE-5358606|reactome:R-SCE-6782210|reactome:R-SCE-69183	refseq:NP_055976.1|ensembl:ENSG00000170540(gene)|ensembl:ENST00000304414(transcript)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006613"(cotranslational protein targeting to membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0071787"(endoplasmic reticulum tubular network formation)|go:"GO:1903371"(regulation of endoplasmic reticulum tubular network organization)|go:"GO:1990809"(endoplasmic reticulum tubular network membrane organization)|interpro:IPR033301|mint:Q15041|go:"GO:0002038"(positive regulation of L-glutamate import across plasma membrane)|refseq:NP_001300787.1	-	crc64:B7C2ECAF5C61CAE7	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:sl00ubCmkTFwW2bznucqEF60I3M559292	rogid:3fjkoyvUx25po7xsPcXgpjEeLJg9606	intact-crc:118A56353B814AF1|rigid:ERVbPUWiIjvEJNHRtyq/VzxEWUk	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q12259	uniprotkb:Q15041	intact:EBI-30776|uniprotkb:D6VYA8|ensemblfungi:YLR108C	intact:EBI-714543|ensembl:ENSP00000306788|uniprotkb:B7Z6S5|uniprotkb:B7Z791|uniprotkb:F5GXP4	psi-mi:yl108_yeast(display_long)|uniprotkb:L2913(orf name)|uniprotkb:YLR108C(locus name)	psi-mi:ar6p1_human(display_long)|uniprotkb:ARL6IP(gene name synonym)|uniprotkb:ARL6IP1(gene name)|psi-mi:ARL6IP1(display_short)|uniprotkb:KIAA0069(gene name synonym)|uniprotkb:ARMER(gene name synonym)|uniprotkb:Apoptotic regulator in the membrane of the endoplasmic reticulum(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551640|imex:IM-24995-3481	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013209.1|sgd:S000004098|dip:DIP-4075N|ensemblfungi:YLR108C(gene)|ensemblfungi:YLR108C_mRNA(transcript)|go:"GO:0005634"(nucleus)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)	refseq:NP_055976.1|ensembl:ENSG00000170540(gene)|ensembl:ENST00000304414(transcript)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006613"(cotranslational protein targeting to membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0071787"(endoplasmic reticulum tubular network formation)|go:"GO:1903371"(regulation of endoplasmic reticulum tubular network organization)|go:"GO:1990809"(endoplasmic reticulum tubular network membrane organization)|interpro:IPR033301|mint:Q15041|go:"GO:0002038"(positive regulation of L-glutamate import across plasma membrane)|refseq:NP_001300787.1	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:CzknxXhhvgMp3J0/oi197EgZ05U559292	rogid:3fjkoyvUx25po7xsPcXgpjEeLJg9606	intact-crc:8DE1A3E0C4CFE0F4|rigid:z/je0n1TVgGyjkTlmk7fJJZoF6Q	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P53296	uniprotkb:Q15041	intact:EBI-3165|uniprotkb:E9P955|ensemblfungi:YGR177C|uniprotkb:D6VUW1	intact:EBI-714543|ensembl:ENSP00000306788|uniprotkb:B7Z6S5|uniprotkb:B7Z791|uniprotkb:F5GXP4	psi-mi:atf2_yeast(display_long)|uniprotkb:ATF2(gene name)|psi-mi:ATF2(display_short)|uniprotkb:"Acetyl-CoA:pregnenolone acetyltransferase"(gene name synonym)|uniprotkb:G7135(orf name)|uniprotkb:YGR177C(locus name)	psi-mi:ar6p1_human(display_long)|uniprotkb:ARL6IP(gene name synonym)|uniprotkb:ARL6IP1(gene name)|psi-mi:ARL6IP1(display_short)|uniprotkb:KIAA0069(gene name synonym)|uniprotkb:ARMER(gene name synonym)|uniprotkb:Apoptotic regulator in the membrane of the endoplasmic reticulum(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551632|imex:IM-24995-3479	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011693.1|sgd:S000003409|ensemblfungi:YGR177C(gene)|ensemblfungi:YGR177C_mRNA(transcript)|go:"GO:0004026"(alcohol O-acetyltransferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0008080"(N-acetyltransferase activity)|go:"GO:0008202"(steroid metabolic process)|go:"GO:0009636"(response to toxic substance)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0034209"(sterol acetylation)|go:"GO:1901089"(acetate ester metabolic process involved in fermentation)|interpro:IPR010828(Alcohol acetyltransferase)|dip:DIP-5544N|mint:P53296	refseq:NP_055976.1|ensembl:ENSG00000170540(gene)|ensembl:ENST00000304414(transcript)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006613"(cotranslational protein targeting to membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0071787"(endoplasmic reticulum tubular network formation)|go:"GO:1903371"(regulation of endoplasmic reticulum tubular network organization)|go:"GO:1990809"(endoplasmic reticulum tubular network membrane organization)|interpro:IPR033301|mint:Q15041|go:"GO:0002038"(positive regulation of L-glutamate import across plasma membrane)|refseq:NP_001300787.1	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:tFI+2rcFXzDfDteDJv8wwBGUh0c559292	rogid:3fjkoyvUx25po7xsPcXgpjEeLJg9606	intact-crc:C67821B7EC17D5A8|rigid:xG/zV4XbXvlA5eYSWH2Ko7n+JJ0	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q15041	uniprotkb:P53845	intact:EBI-714543|ensembl:ENSP00000306788|uniprotkb:B7Z6S5|uniprotkb:B7Z791|uniprotkb:F5GXP4	intact:EBI-28230|uniprotkb:D6W0T0|ensemblfungi:YNL263C	psi-mi:ar6p1_human(display_long)|uniprotkb:ARL6IP(gene name synonym)|uniprotkb:ARL6IP1(gene name)|psi-mi:ARL6IP1(display_short)|uniprotkb:KIAA0069(gene name synonym)|uniprotkb:ARMER(gene name synonym)|uniprotkb:Apoptotic regulator in the membrane of the endoplasmic reticulum(gene name synonym)	psi-mi:yif1_yeast(display_long)|uniprotkb:YNL263C(locus name)|uniprotkb:N0820(orf name)|uniprotkb:YIF1(gene name)|psi-mi:YIF1(display_short)|uniprotkb:YIP1-interacting factor 1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551636|imex:IM-24995-3480	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055976.1|ensembl:ENSG00000170540(gene)|ensembl:ENST00000304414(transcript)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006613"(cotranslational protein targeting to membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0071787"(endoplasmic reticulum tubular network formation)|go:"GO:1903371"(regulation of endoplasmic reticulum tubular network organization)|go:"GO:1990809"(endoplasmic reticulum tubular network membrane organization)|interpro:IPR033301|mint:Q15041|go:"GO:0002038"(positive regulation of L-glutamate import across plasma membrane)|refseq:NP_001300787.1	refseq:NP_014136.1|sgd:S000005207|dip:DIP-1729N|ensemblfungi:YNL263C(gene)|ensemblfungi:YNL263C_mRNA(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0015031"(protein transport)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0030173"(integral component of Golgi membrane)|interpro:IPR005578(Hrf1)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:3fjkoyvUx25po7xsPcXgpjEeLJg9606	rogid:HEs4ZRFWRAkXinwmuLiWGpmUqsM559292	intact-crc:9D80BB581A59E512|rigid:8t8aGnhVCEYy1sCcPsi+mIFoPcw	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q15415	uniprotkb:P38340	intact:EBI-8642021|uniprotkb:B2R916|intact:MINT-8163253|ensembl:ENSP00000250831|ensembl:ENSP00000307155	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:rby1f_human(display_long)|uniprotkb:RBMY1F(gene name)|psi-mi:RBMY1F(display_short)|uniprotkb:RBMY1J(gene name)|psi-mi:RBMY1J(display_short)|uniprotkb:Y chromosome RNA recognition motif 2(gene name synonym)|uniprotkb:YRRM2(gene name synonym)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551660|imex:IM-24995-3486	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001290339.1|refseq:NP_001006117.2|refseq:NP_689798.1|ensembl:ENSG00000169800(gene)|ensembl:ENSG00000226941(gene)|ensembl:ENST00000250831(transcript)|ensembl:ENST00000303766(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016607"(nuclear speck)|go:"GO:0042802"(identical protein binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012604(RBM1CTR)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F	-	comment:mint	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:lEyv+LmtOFRifaC5g6jDlh5WCnM9606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:3ECAAC347FBDCA28|rigid:wQHrJT0tIFinJYuQMAAo3VWix+M	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q15415	uniprotkb:P36084	intact:EBI-8642021|uniprotkb:B2R916|intact:MINT-8163253|ensembl:ENSP00000250831|ensembl:ENSP00000307155	intact:EBI-11612|ensemblfungi:YKL074C|uniprotkb:D6VXL2	psi-mi:rby1f_human(display_long)|uniprotkb:RBMY1F(gene name)|psi-mi:RBMY1F(display_short)|uniprotkb:RBMY1J(gene name)|psi-mi:RBMY1J(display_short)|uniprotkb:Y chromosome RNA recognition motif 2(gene name synonym)|uniprotkb:YRRM2(gene name synonym)	psi-mi:mud2_yeast(display_long)|uniprotkb:MUD2(gene name)|psi-mi:MUD2(display_short)|uniprotkb:YKL358(orf name)|uniprotkb:YKL074C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551656|imex:IM-24995-3485	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001290339.1|refseq:NP_001006117.2|refseq:NP_689798.1|ensembl:ENSG00000169800(gene)|ensembl:ENSG00000226941(gene)|ensembl:ENST00000250831(transcript)|ensembl:ENST00000303766(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016607"(nuclear speck)|go:"GO:0042802"(identical protein binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012604(RBM1CTR)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979	go:"GO:0000243"(commitment complex)|go:"GO:0000348"(mRNA branch site recognition)|go:"GO:0003729"(mRNA binding)|go:"GO:0008187"(poly-pyrimidine tract binding)|go:"GO:0016607"(nuclear speck)|ensemblfungi:YKL074C(gene)|go:"GO:0030628"(pre-mRNA 3'-splice site binding)|go:"GO:0045131"(pre-mRNA branch point binding)|go:"GO:0071004"(U2-type prespliceosome)|ensemblfungi:YKL074C_mRNA(transcript)|go:"GO:0089701"(U2AF complex)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|refseq:NP_012849.1|sgd:S000001557|mint:P36084|dip:DIP-758N	-	comment:mint	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:lEyv+LmtOFRifaC5g6jDlh5WCnM9606	rogid:l/aBULMxdezuufNxUE5qqnYEN1Y559292	intact-crc:197EFD8B4192EFE4|rigid:w65kkiCHGlmfPuALqJtb8HWbwCA	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P32614	uniprotkb:Q15102	intact:EBI-22366|uniprotkb:D3DLK3|ensemblfungi:YEL047C	intact:EBI-711522|uniprotkb:Q53X88|ensembl:ENSP00000262890|ensembl:ENSP00000444935	psi-mi:frds_yeast(display_long)|uniprotkb:FRD1(gene name)|psi-mi:FRD1(display_short)|uniprotkb:FAD-dependent oxidoreductase(gene name synonym)|uniprotkb:FRDS(gene name synonym)|uniprotkb:FRDS1(gene name synonym)|uniprotkb:NADH-dependent fumarate reductase(gene name synonym)|uniprotkb:Soluble fumarate reductase, cytoplasmic isozyme(gene name synonym)|uniprotkb:SYGP-ORF35(orf name)|uniprotkb:YEL047C(locus name)	psi-mi:pa1b3_human(display_long)|uniprotkb:PAFAH1B3(gene name)|psi-mi:PAFAH1B3(display_short)|uniprotkb:PAFAHG(gene name synonym)|uniprotkb:PAF acetylhydrolase 29 kDa subunit(gene name synonym)|uniprotkb:PAF-AH subunit gamma(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551644|imex:IM-24995-3482	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000000773|refseq:NP_010867.3|dip:DIP-5287N|mint:P32614|ensemblfungi:YEL047C(gene)|ensemblfungi:YEL047C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010181"(FMN binding)|go:"GO:0016156"("fumarate reductase (NADH) activity")|go:"GO:0071454"(cellular response to anoxia)|interpro:IPR003953(Fumarate reductase/succinate dehydrogenase flavoprotein, N-terminal)|interpro:IPR010960(Flavocytochrome c)|interpro:IPR027477|interpro:IPR036188	go:"GO:0016042"(lipid catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0047179"(platelet-activating factor acetyltransferase activity)|interpro:IPR013830(Esterase, SGNH hydrolase-type)|interpro:IPR036514|mint:Q15102|reactome:R-HSA-6811436|go:"GO:0005829"(cytosol)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0008247"(1-alkyl-2-acetylglycerophosphocholine esterase complex)|go:"GO:0016020"(membrane)|ensembl:ENSG00000079462(gene)|ensembl:ENST00000262890(transcript)|ensembl:ENST00000538771(transcript)|go:"GO:0003847"(1-alkyl-2-acetylglycerophosphocholine esterase activity)|go:"GO:0005737"(cytoplasm)|refseq:NP_001139411.1|refseq:NP_001139412.1|refseq:NP_002564.1	-	crc64:63C30B39252DC935	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:hkn/l2LN9LMWWw+e7kXvRXVqvr4559292	rogid:yxVKkXAs2AmH+fZFUW+hZN889k89606	intact-crc:7E0C46FED3CFCE27|rigid:sZ95JGMiTAmt5QKEhbl5f/wX+OE	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q15311	uniprotkb:Q07978	intact:EBI-749285|uniprotkb:D3DUI0|ensembl:ENSP00000019317|ensembl:ENSP00000372924	intact:EBI-38683|uniprotkb:D6VY33|ensemblfungi:YLR031W	psi-mi:rbp1_human(display_long)|uniprotkb:Ral-interacting protein 1(gene name synonym)|uniprotkb:76 kDa Ral-interacting protein(gene name synonym)|uniprotkb:Dinitrophenyl S-glutathione ATPase(gene name synonym)|uniprotkb:RALBP1(gene name)|psi-mi:RALBP1(display_short)|uniprotkb:RLIP1(gene name synonym)|uniprotkb:RLIP76(gene name synonym)|uniprotkb:RLIP(gene name synonym)	psi-mi:yl031_yeast(display_long)|uniprotkb:YLR031W(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551648|imex:IM-24995-3483	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006779.1|ensembl:ENSG00000017797(gene)|ensembl:ENST00000019317(transcript)|ensembl:ENST00000383432(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0006935"(chemotaxis)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008559"(ABC-type xenobiotic transporter activity)|go:"GO:0015431"(ABC-type glutathione S-conjugate transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032489"(regulation of Cdc42 protein signal transduction)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0055085"(transmembrane transport)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:1900753"(doxorubicin transport)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR000198(RhoGAP)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR039767|mint:Q15311|rcsb pdb:2KWH|rcsb pdb:2KWI|rcsb pdb:2MBG|rcsb pdb:6ZQT|rcsb pdb:6ZRN|reactome:R-HSA-9013148|reactome:R-HSA-9013149	sgd:S000004021|refseq:NP_013131.1|dip:DIP-4435N|ensemblfungi:YLR031W(gene)|ensemblfungi:YLR031W_mRNA(transcript)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:6u1yy+UdGWJbJ9SiItSAp+CqeVk9606	rogid:T3r2tgTMVd+abiwf7/Ccb/QJ2ZQ559292	intact-crc:2C338F6F6FB0D319|rigid:0n9EzCn+UfVIyeu8uLmWUuWgaZ4	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q15311	uniprotkb:P40014	intact:EBI-749285|uniprotkb:D3DUI0|ensembl:ENSP00000019317|ensembl:ENSP00000372924	intact:EBI-22458|uniprotkb:D3DLR6|ensemblfungi:YER018C	psi-mi:rbp1_human(display_long)|uniprotkb:Ral-interacting protein 1(gene name synonym)|uniprotkb:76 kDa Ral-interacting protein(gene name synonym)|uniprotkb:Dinitrophenyl S-glutathione ATPase(gene name synonym)|uniprotkb:RALBP1(gene name)|psi-mi:RALBP1(display_short)|uniprotkb:RLIP1(gene name synonym)|uniprotkb:RLIP76(gene name synonym)|uniprotkb:RLIP(gene name synonym)	psi-mi:spc25_yeast(display_long)|uniprotkb:YER018C(locus name)|uniprotkb:SPC25(gene name)|psi-mi:SPC25(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551652|imex:IM-24995-3484	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006779.1|ensembl:ENSG00000017797(gene)|ensembl:ENST00000019317(transcript)|ensembl:ENST00000383432(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0006935"(chemotaxis)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008559"(ABC-type xenobiotic transporter activity)|go:"GO:0015431"(ABC-type glutathione S-conjugate transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032489"(regulation of Cdc42 protein signal transduction)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0055085"(transmembrane transport)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:1900753"(doxorubicin transport)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR000198(RhoGAP)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR039767|mint:Q15311|rcsb pdb:2KWH|rcsb pdb:2KWI|rcsb pdb:2MBG|rcsb pdb:6ZQT|rcsb pdb:6ZRN|reactome:R-HSA-9013148|reactome:R-HSA-9013149	refseq:NP_010934.3|sgd:S000000820|dip:DIP-2990N|mint:P40014|ensemblfungi:YER018C(gene)|ensemblfungi:YER018C_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0051301"(cell division)|go:"GO:0098653"(centromere clustering)|interpro:IPR038066|rcsb pdb:2FTX|rcsb pdb:2FV4|rcsb pdb:4GEQ|rcsb pdb:5T6J|rcsb pdb:5TCS|rcsb pdb:5TD8|rcsb pdb:7KDF	-	-	crc64:1BED6CCFF330A5D8	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:6u1yy+UdGWJbJ9SiItSAp+CqeVk9606	rogid:i5gKRZA7GAjnCVzuX/qP8YmpQRA559292	intact-crc:691D5F62D9912925|rigid:HtFQGc/1uQod6UrVVKxZtrNLaK0	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q15427	uniprotkb:P53829	intact:EBI-348469|ensembl:ENSP00000271628|intact:EBI-1047735|uniprotkb:Q5SZ63	intact:EBI-28306|uniprotkb:D6W0Q5|ensemblfungi:YNL288W	psi-mi:sf3b4_human(display_long)|uniprotkb:SF3B4(gene name)|psi-mi:SF3B4(display_short)|uniprotkb:SAP49(gene name synonym)|uniprotkb:Spliceosome-associated protein 49(gene name synonym)|uniprotkb:Pre-mRNA-splicing factor SF3b 49 kDa subunit(gene name synonym)	psi-mi:caf40_yeast(display_long)|uniprotkb:YNL288W(locus name)|uniprotkb:N0540(orf name)|uniprotkb:40 kDa CCR4-associated factor(gene name synonym)|uniprotkb:CAF40(gene name)|psi-mi:CAF40(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551676|imex:IM-24995-3490	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005841.1|ensembl:ENSG00000143368(gene)|ensembl:ENST00000271628(transcript)|rcsb pdb:6QX9|rcsb pdb:6Y53|rcsb pdb:6Y5Q|rcsb pdb:7ABG|rcsb pdb:7ABH|rcsb pdb:7ABI|rcsb pdb:7DVQ|reactome:R-HSA-72163|reactome:R-HSA-72165|rcsb pdb:6AHD|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:1990935"(splicing factor binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034158|go:"GO:0000375"(RNA splicing, via transesterification reactions)|interpro:IPR034159|interpro:IPR035979|mint:Q15427|rcsb pdb:1X5T|rcsb pdb:5GVQ|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0	refseq:NP_014111.1|sgd:S000005232|dip:DIP-1995N|mint:P53829|ensemblfungi:YNL288W(gene)|ensemblfungi:YNL288W_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR007216(Cell differentiation, Rcd1-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:4CV5	-	-	crc64:F3DBABE6AD3C7F3C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Jgy6WmBFKkphpZLLte2GgsagUVI9606	rogid:etuSSgFGQOcgxPDexEXUqQg6H5s559292	intact-crc:2E41386BB5047818|rigid:dEnI/usfnIkEGrMpac3rNG74SFw	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q15427	uniprotkb:P20081	intact:EBI-348469|ensembl:ENSP00000271628|intact:EBI-1047735|uniprotkb:Q5SZ63	intact:EBI-6961|uniprotkb:D6W147|ensemblfungi:YNL135C	psi-mi:sf3b4_human(display_long)|uniprotkb:SF3B4(gene name)|psi-mi:SF3B4(display_short)|uniprotkb:SAP49(gene name synonym)|uniprotkb:Spliceosome-associated protein 49(gene name synonym)|uniprotkb:Pre-mRNA-splicing factor SF3b 49 kDa subunit(gene name synonym)	psi-mi:fkbp_yeast(display_long)|uniprotkb:RBP1(gene name synonym)|uniprotkb:N1213(orf name)|uniprotkb:N1845(orf name)|uniprotkb:YNL135C(locus name)|uniprotkb:FPR1(gene name)|psi-mi:FPR1(display_short)|uniprotkb:FKB1(gene name synonym)|uniprotkb:Peptidyl-prolyl cis-trans isomerase(gene name synonym)|uniprotkb:Rapamycin-binding protein(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551664|imex:IM-24995-3487	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005841.1|ensembl:ENSG00000143368(gene)|ensembl:ENST00000271628(transcript)|rcsb pdb:6QX9|rcsb pdb:6Y53|rcsb pdb:6Y5Q|rcsb pdb:7ABG|rcsb pdb:7ABH|rcsb pdb:7ABI|rcsb pdb:7DVQ|reactome:R-HSA-72163|reactome:R-HSA-72165|rcsb pdb:6AHD|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:1990935"(splicing factor binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034158|go:"GO:0000375"(RNA splicing, via transesterification reactions)|interpro:IPR034159|interpro:IPR035979|mint:Q15427|rcsb pdb:1X5T|rcsb pdb:5GVQ|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0	refseq:NP_014264.1|sgd:S000005079|dip:DIP-1263N|mint:P20081|ensemblfungi:YNL135C(gene)|ensemblfungi:YNL135C_mRNA(transcript)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005527"(macrolide binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006325"(chromatin organization)|go:"GO:0006457"(protein folding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:1901710"(regulation of homoserine biosynthetic process)|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)|rcsb pdb:1YAT	-	-	crc64:65C134830D300C06	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Jgy6WmBFKkphpZLLte2GgsagUVI9606	rogid:8afvGSk+mPghtqkVoWd2rHJXXhQ559292	intact-crc:5BD8916B31F0B3B0|rigid:225teJT55udQNVL3ZYsd/JkGmp0	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q15427	intact:EBI-11522220	intact:EBI-348469|ensembl:ENSP00000271628|intact:EBI-1047735|uniprotkb:Q5SZ63	-	psi-mi:sf3b4_human(display_long)|uniprotkb:SF3B4(gene name)|psi-mi:SF3B4(display_short)|uniprotkb:SAP49(gene name synonym)|uniprotkb:Spliceosome-associated protein 49(gene name synonym)|uniprotkb:Pre-mRNA-splicing factor SF3b 49 kDa subunit(gene name synonym)	psi-mi:lsb3(display_short)|psi-mi:EBI-11522220(display_long)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551668|imex:IM-24995-3488	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005841.1|ensembl:ENSG00000143368(gene)|ensembl:ENST00000271628(transcript)|rcsb pdb:6QX9|rcsb pdb:6Y53|rcsb pdb:6Y5Q|rcsb pdb:7ABG|rcsb pdb:7ABH|rcsb pdb:7ABI|rcsb pdb:7DVQ|reactome:R-HSA-72163|reactome:R-HSA-72165|rcsb pdb:6AHD|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:1990935"(splicing factor binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034158|go:"GO:0000375"(RNA splicing, via transesterification reactions)|interpro:IPR034159|interpro:IPR035979|mint:Q15427|rcsb pdb:1X5T|rcsb pdb:5GVQ|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0	-	-	-	no-uniprot-update:	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Jgy6WmBFKkphpZLLte2GgsagUVI9606	rogid:lsGJZWImagMoiiCZztCcxCn2LlU4932	intact-crc:389CF80066351633|rigid:NuuZz3pXah3Iu9b4yqvrb3ZKfZE	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q15427	uniprotkb:P38340	intact:EBI-348469|ensembl:ENSP00000271628|intact:EBI-1047735|uniprotkb:Q5SZ63	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:sf3b4_human(display_long)|uniprotkb:SF3B4(gene name)|psi-mi:SF3B4(display_short)|uniprotkb:SAP49(gene name synonym)|uniprotkb:Spliceosome-associated protein 49(gene name synonym)|uniprotkb:Pre-mRNA-splicing factor SF3b 49 kDa subunit(gene name synonym)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551672|imex:IM-24995-3489	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005841.1|ensembl:ENSG00000143368(gene)|ensembl:ENST00000271628(transcript)|rcsb pdb:6QX9|rcsb pdb:6Y53|rcsb pdb:6Y5Q|rcsb pdb:7ABG|rcsb pdb:7ABH|rcsb pdb:7ABI|rcsb pdb:7DVQ|reactome:R-HSA-72163|reactome:R-HSA-72165|rcsb pdb:6AHD|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:1990935"(splicing factor binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034158|go:"GO:0000375"(RNA splicing, via transesterification reactions)|interpro:IPR034159|interpro:IPR035979|mint:Q15427|rcsb pdb:1X5T|rcsb pdb:5GVQ|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F	-	-	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:Jgy6WmBFKkphpZLLte2GgsagUVI9606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:691FEEC25C57C9B2|rigid:3VKOeIx9t1GaLwUpa67IqPqIbOA	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q06676	uniprotkb:Q15437	intact:EBI-30298|uniprotkb:D6VSV0|ensemblfungi:YDR319C	intact:EBI-742673|uniprotkb:Q5W183|uniprotkb:Q9BS15|uniprotkb:Q9BSI2|uniprotkb:Q9H1D7|intact:EBI-1048165|uniprotkb:Q503A9|uniprotkb:D3DW33|ensembl:ENSP00000262544|ensembl:ENSP00000338844|ensembl:ENSP00000366685|ensembl:ENSP00000497473	psi-mi:yft2_yeast(display_long)|uniprotkb:YFT2(gene name)|psi-mi:YFT2(display_short)|uniprotkb:FIT2A(gene name synonym)|uniprotkb:YDR319C(locus name)|uniprotkb:FIT family protein YFT2(gene name synonym)	psi-mi:sc23b_human(display_long)|uniprotkb:SEC23-related protein B(gene name synonym)|uniprotkb:SEC23B(gene name)|psi-mi:SEC23B(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551696|imex:IM-24995-3495	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010605.1|sgd:S000002727|dip:DIP-4731N|reactome:R-SCE-8964572|ensemblfungi:YDR319C(gene)|ensemblfungi:YDR319C_mRNA(transcript)|go:"GO:0005773"(vacuole)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0008654"(phospholipid biosynthetic process)|go:"GO:0016818"(hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides)|go:"GO:0019915"(lipid storage)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0034389"(lipid droplet organization)|go:"GO:0140042"(lipid droplet formation)|go:"GO:1900480"(regulation of diacylglycerol biosynthetic process)|go:"GO:1900481"(negative regulation of diacylglycerol biosynthetic process)|interpro:IPR019388	refseq:NP_001166216.1|refseq:NP_006354.2|refseq:NP_116780.1|refseq:NP_116781.1|ensembl:ENSG00000101310(gene)|ensembl:ENST00000262544(transcript)|ensembl:ENST00000336714(transcript)|ensembl:ENST00000377465(transcript)|ensembl:ENST00000650089(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008270"(zinc ion binding)|go:"GO:0012505"(endomembrane system)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0090110"(COPII-coated vesicle cargo loading)|go:"GO:0070971"(endoplasmic reticulum exit site)|interpro:IPR006895(Zinc finger, Sec23/Sec24-type)|interpro:IPR006896(Sec23/Sec24 trunk region)|interpro:IPR006900(Sec23/Sec24 helical region)|interpro:IPR007123(Gelsolin region)|interpro:IPR012990(Sec23/Sec24 beta-sandwich)|interpro:IPR029006|interpro:IPR036174|interpro:IPR036175|interpro:IPR036180|interpro:IPR036465|interpro:IPR037364|interpro:IPR037550|mint:Q15437|refseq:XP_016883082.1	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:gy1kXEPAQZisfcLxF3V95W1JR60559292	rogid:+3KZ/1jjziSgJRcr81Axquofkl49606	intact-crc:C366878C2BD74C99|rigid:aA65udexRxRSI7Ii6EO8Hq/9uCE	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P39724	uniprotkb:Q15437	intact:EBI-2343154|uniprotkb:D6VPH0|ensemblfungi:YAL046C	intact:EBI-742673|uniprotkb:Q5W183|uniprotkb:Q9BS15|uniprotkb:Q9BSI2|uniprotkb:Q9H1D7|intact:EBI-1048165|uniprotkb:Q503A9|uniprotkb:D3DW33|ensembl:ENSP00000262544|ensembl:ENSP00000338844|ensembl:ENSP00000366685|ensembl:ENSP00000497473	psi-mi:bol3_yeast(display_long)|uniprotkb:BOL3(gene name)|psi-mi:BOL3(display_short)|uniprotkb:AIM1(gene name synonym)|uniprotkb:Altered inheritance of mitochondria protein 1(gene name synonym)|uniprotkb:YAL046C(locus name)	psi-mi:sc23b_human(display_long)|uniprotkb:SEC23-related protein B(gene name synonym)|uniprotkb:SEC23B(gene name)|psi-mi:SEC23B(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551692|imex:IM-24995-3494	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009353.1|sgd:S000000044|interpro:IPR002634(BolA-like protein)|interpro:IPR036065|mint:P39724|ensemblfungi:YAL046C(gene)|ensemblfungi:YAL046C_mRNA(transcript)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0106035"(protein maturation by [4Fe-4S] cluster transfer)	refseq:NP_001166216.1|refseq:NP_006354.2|refseq:NP_116780.1|refseq:NP_116781.1|ensembl:ENSG00000101310(gene)|ensembl:ENST00000262544(transcript)|ensembl:ENST00000336714(transcript)|ensembl:ENST00000377465(transcript)|ensembl:ENST00000650089(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008270"(zinc ion binding)|go:"GO:0012505"(endomembrane system)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0090110"(COPII-coated vesicle cargo loading)|go:"GO:0070971"(endoplasmic reticulum exit site)|interpro:IPR006895(Zinc finger, Sec23/Sec24-type)|interpro:IPR006896(Sec23/Sec24 trunk region)|interpro:IPR006900(Sec23/Sec24 helical region)|interpro:IPR007123(Gelsolin region)|interpro:IPR012990(Sec23/Sec24 beta-sandwich)|interpro:IPR029006|interpro:IPR036174|interpro:IPR036175|interpro:IPR036180|interpro:IPR036465|interpro:IPR037364|interpro:IPR037550|mint:Q15437|refseq:XP_016883082.1	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:MLrW6Iu4YKXf87O1cyx5bY03VdE559292	rogid:+3KZ/1jjziSgJRcr81Axquofkl49606	intact-crc:D629ADAF83980F56|rigid:8MkNnnAeJJBcyFBfag9U5MtleHo	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q15427	uniprotkb:P25343	intact:EBI-348469|ensembl:ENSP00000271628|intact:EBI-1047735|uniprotkb:Q5SZ63	intact:EBI-14490|uniprotkb:D6VR18|ensemblfungi:YCR009C	psi-mi:sf3b4_human(display_long)|uniprotkb:SF3B4(gene name)|psi-mi:SF3B4(display_short)|uniprotkb:SAP49(gene name synonym)|uniprotkb:Spliceosome-associated protein 49(gene name synonym)|uniprotkb:Pre-mRNA-splicing factor SF3b 49 kDa subunit(gene name synonym)	psi-mi:rv161_yeast(display_long)|uniprotkb:RVS161(gene name)|psi-mi:RVS161(display_short)|uniprotkb:END6(gene name synonym)|uniprotkb:SPE161(gene name synonym)|uniprotkb:YCR009C(locus name)|uniprotkb:YCR9C(orf name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551680|imex:IM-24995-3491	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005841.1|ensembl:ENSG00000143368(gene)|ensembl:ENST00000271628(transcript)|rcsb pdb:6QX9|rcsb pdb:6Y53|rcsb pdb:6Y5Q|rcsb pdb:7ABG|rcsb pdb:7ABH|rcsb pdb:7ABI|rcsb pdb:7DVQ|reactome:R-HSA-72163|reactome:R-HSA-72165|rcsb pdb:6AHD|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:1990935"(splicing factor binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034158|go:"GO:0000375"(RNA splicing, via transesterification reactions)|interpro:IPR034159|interpro:IPR035979|mint:Q15427|rcsb pdb:1X5T|rcsb pdb:5GVQ|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0	ensemblfungi:YCR009C(gene)|ensemblfungi:YCR009C_mRNA(transcript)|go:"GO:0000747"(conjugation with cellular fusion)|go:"GO:0005829"(cytosol)|go:"GO:0005937"(mating projection)|go:"GO:0006897"(endocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030479"(actin cortical patch)|go:"GO:0031097"(medial cortex)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0042594"(response to starvation)|go:"GO:0043332"(mating projection tip)|go:"GO:0045121"(membrane raft)|go:"GO:0051666"(actin cortical patch localization)|go:"GO:0060988"(lipid tube assembly)|go:"GO:0097320"(plasma membrane tubulation)|go:"GO:1990528"(Rvs161p-Rvs167p complex)|interpro:IPR004148(BAR)|interpro:IPR027267|go:"GO:0006970"(response to osmotic stress)|interpro:IPR037429|refseq:NP_009935.1|sgd:S000000602|mint:P25343|dip:DIP-1601N	-	-	crc64:B35EA00E0C900E2D	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Jgy6WmBFKkphpZLLte2GgsagUVI9606	rogid:IdjO8RS5vcYMeGxuoPoa/5e7QJQ559292	intact-crc:15DA0B067C55D516|rigid:bknMPZefJNeyCajFqg2U1zUynFk	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q15427	uniprotkb:P32831	intact:EBI-348469|ensembl:ENSP00000271628|intact:EBI-1047735|uniprotkb:Q5SZ63	intact:EBI-12002|ensemblfungi:YBR212W|uniprotkb:D6VQK8	psi-mi:sf3b4_human(display_long)|uniprotkb:SF3B4(gene name)|psi-mi:SF3B4(display_short)|uniprotkb:SAP49(gene name synonym)|uniprotkb:Spliceosome-associated protein 49(gene name synonym)|uniprotkb:Pre-mRNA-splicing factor SF3b 49 kDa subunit(gene name synonym)	psi-mi:ngr1_yeast(display_long)|uniprotkb:NGR1(gene name)|psi-mi:NGR1(display_short)|uniprotkb:RBP1(gene name synonym)|uniprotkb:YBR212W(locus name)|uniprotkb:YBR1459(orf name)|uniprotkb:RNA-binding protein RBP1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551684|imex:IM-24995-3492	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005841.1|ensembl:ENSG00000143368(gene)|ensembl:ENST00000271628(transcript)|rcsb pdb:6QX9|rcsb pdb:6Y53|rcsb pdb:6Y5Q|rcsb pdb:7ABG|rcsb pdb:7ABH|rcsb pdb:7ABI|rcsb pdb:7DVQ|reactome:R-HSA-72163|reactome:R-HSA-72165|rcsb pdb:6AHD|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:1990935"(splicing factor binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034158|go:"GO:0000375"(RNA splicing, via transesterification reactions)|interpro:IPR034159|interpro:IPR035979|mint:Q15427|rcsb pdb:1X5T|rcsb pdb:5GVQ|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0	ensemblfungi:YBR212W(gene)|ensemblfungi:YBR212W_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|refseq:NP_009771.3|sgd:S000000416|mint:P32831|dip:DIP-5160N	-	-	crc64:12F64EC4C5716750	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Jgy6WmBFKkphpZLLte2GgsagUVI9606	rogid:MCNbYrmWkUp7dAyKpebSKsIzOxA559292	intact-crc:FFB1A7770C538D61|rigid:WSu9Xoaj+gpfen6jYmc5WJVxJlk	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q15437	uniprotkb:P22215	intact:EBI-742673|uniprotkb:Q5W183|uniprotkb:Q9BS15|uniprotkb:Q9BSI2|uniprotkb:Q9H1D7|intact:EBI-1048165|uniprotkb:Q503A9|uniprotkb:D3DW33|ensembl:ENSP00000262544|ensembl:ENSP00000338844|ensembl:ENSP00000366685|ensembl:ENSP00000497473	intact:EBI-17397|uniprotkb:D6W307|ensemblfungi:YOR307C	psi-mi:sc23b_human(display_long)|uniprotkb:SEC23-related protein B(gene name synonym)|uniprotkb:SEC23B(gene name)|psi-mi:SEC23B(display_short)	psi-mi:sly41_yeast(display_long)|uniprotkb:O5663(orf name)|uniprotkb:YOR307C(locus name)|uniprotkb:SLY41(gene name)|psi-mi:SLY41(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551688|imex:IM-24995-3493	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001166216.1|refseq:NP_006354.2|refseq:NP_116780.1|refseq:NP_116781.1|ensembl:ENSG00000101310(gene)|ensembl:ENST00000262544(transcript)|ensembl:ENST00000336714(transcript)|ensembl:ENST00000377465(transcript)|ensembl:ENST00000650089(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008270"(zinc ion binding)|go:"GO:0012505"(endomembrane system)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0090110"(COPII-coated vesicle cargo loading)|go:"GO:0070971"(endoplasmic reticulum exit site)|interpro:IPR006895(Zinc finger, Sec23/Sec24-type)|interpro:IPR006896(Sec23/Sec24 trunk region)|interpro:IPR006900(Sec23/Sec24 helical region)|interpro:IPR007123(Gelsolin region)|interpro:IPR012990(Sec23/Sec24 beta-sandwich)|interpro:IPR029006|interpro:IPR036174|interpro:IPR036175|interpro:IPR036180|interpro:IPR036465|interpro:IPR037364|interpro:IPR037550|mint:Q15437|refseq:XP_016883082.1	refseq:NP_014952.1|sgd:S000005834|ensemblfungi:YOR307C(gene)|ensemblfungi:YOR307C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0015297"(antiporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0089721"(phosphoenolpyruvate transmembrane transporter activity)|go:"GO:1990536"(phosphoenolpyruvate transmembrane import into Golgi lumen)|interpro:IPR004696(Tpt phosphate/phosphoenolpyruvate translocator)|interpro:IPR004853(Protein of unknown function DUF250)|dip:DIP-2919N	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:+3KZ/1jjziSgJRcr81Axquofkl49606	rogid:ZlrKRnUmlnFI2o8e365rgea//gA559292	intact-crc:61780897C42D911F|rigid:CEqncGa+9X+oy3T+p0p0cAwbhdo	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P53933	uniprotkb:Q15642-2	intact:EBI-28798|uniprotkb:D6W186|ensemblfungi:YNL094W	intact:EBI-6550597|ensembl:ENSP00000320493	psi-mi:app1_yeast(display_long)|uniprotkb:APP1(gene name)|psi-mi:APP1(display_short)|uniprotkb:Actin patch protein 1(gene name synonym)|uniprotkb:N2219(orf name)|uniprotkb:YNL094W(locus name)	psi-mi:q15642-2(display_long)|uniprotkb:A(isoform synonym)|uniprotkb:W(isoform synonym)|uniprotkb:TRIP10(gene name)|psi-mi:TRIP10(display_short)|uniprotkb:CIP4(gene name synonym)|uniprotkb:STOT(gene name synonym)|uniprotkb:STP(gene name synonym)|uniprotkb:Protein Felic(gene name synonym)|uniprotkb:Salt tolerant protein(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 10(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551712|imex:IM-24995-3499	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014305.1|sgd:S000005038|dip:DIP-2006N|mint:P53933|ensemblfungi:YNL094W(gene)|ensemblfungi:YNL094W_mRNA(transcript)|go:"GO:0008195"(phosphatidate phosphatase activity)|go:"GO:0030479"(actin cortical patch)|go:"GO:0044255"(cellular lipid metabolic process)|interpro:IPR017210(Uncharacterised conserved protein UCP037464, actin patch protein 1)|interpro:IPR019236	uniprotkb:Q15642-2(isoform-parent)|ensembl:ENSG00000125733(gene)|ensembl:ENST00000313285(transcript)|intact:EBI-739936(isoform-parent)	-	crc64:B85C525548BA34BC	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:4ORrWVN2DOL+59LI2qWcKYYVfcE559292	rogid:FppLeIANQu5tcNbD11u+F0kSOBQ9606	intact-crc:7B63613343FEE1D3|rigid:eMVEToYrW+Tmvt0fj+E8dB1WpiE	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P53337	uniprotkb:Q15437	intact:EBI-23662|uniprotkb:E9P8T4|uniprotkb:D6VV61|ensemblfungi:YGR284C	intact:EBI-742673|uniprotkb:Q5W183|uniprotkb:Q9BS15|uniprotkb:Q9BSI2|uniprotkb:Q9H1D7|intact:EBI-1048165|uniprotkb:Q503A9|uniprotkb:D3DW33|ensembl:ENSP00000262544|ensembl:ENSP00000338844|ensembl:ENSP00000366685|ensembl:ENSP00000497473	psi-mi:erv29_yeast(display_long)|uniprotkb:ERV29(gene name)|psi-mi:ERV29(display_short)|uniprotkb:YGR284C(locus name)	psi-mi:sc23b_human(display_long)|uniprotkb:SEC23-related protein B(gene name synonym)|uniprotkb:SEC23B(gene name)|psi-mi:SEC23B(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551700|imex:IM-24995-3496	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011800.3|sgd:S000003516|dip:DIP-8110N|mint:P53337|ensemblfungi:YGR284C(gene)|ensemblfungi:YGR284C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0097020"(COPII receptor activity)|interpro:IPR002995(Surfeit locus 4)|reactome:R-SCE-6798695|reactome:R-SCE-6811434	refseq:NP_001166216.1|refseq:NP_006354.2|refseq:NP_116780.1|refseq:NP_116781.1|ensembl:ENSG00000101310(gene)|ensembl:ENST00000262544(transcript)|ensembl:ENST00000336714(transcript)|ensembl:ENST00000377465(transcript)|ensembl:ENST00000650089(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008270"(zinc ion binding)|go:"GO:0012505"(endomembrane system)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0090110"(COPII-coated vesicle cargo loading)|go:"GO:0070971"(endoplasmic reticulum exit site)|interpro:IPR006895(Zinc finger, Sec23/Sec24-type)|interpro:IPR006896(Sec23/Sec24 trunk region)|interpro:IPR006900(Sec23/Sec24 helical region)|interpro:IPR007123(Gelsolin region)|interpro:IPR012990(Sec23/Sec24 beta-sandwich)|interpro:IPR029006|interpro:IPR036174|interpro:IPR036175|interpro:IPR036180|interpro:IPR036465|interpro:IPR037364|interpro:IPR037550|mint:Q15437|refseq:XP_016883082.1	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:vlRDf0B9mDUXU6M2tLAiWqX4wN8559292	rogid:+3KZ/1jjziSgJRcr81Axquofkl49606	intact-crc:0047EE3DF09DC130|rigid:6ziWyI9R7/6JLtW/u8QQLPdTMm4	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P36125	uniprotkb:Q15437	intact:EBI-26378|uniprotkb:D6VX95|ensemblfungi:YKR030W	intact:EBI-742673|uniprotkb:Q5W183|uniprotkb:Q9BS15|uniprotkb:Q9BSI2|uniprotkb:Q9H1D7|intact:EBI-1048165|uniprotkb:Q503A9|uniprotkb:D3DW33|ensembl:ENSP00000262544|ensembl:ENSP00000338844|ensembl:ENSP00000366685|ensembl:ENSP00000497473	psi-mi:gmh1_yeast(display_long)|uniprotkb:YKR030W(locus name)|uniprotkb:GEA1-6 membrane-associated high-copy suppressor protein 1(gene name synonym)|uniprotkb:GMH1(gene name)|psi-mi:GMH1(display_short)|uniprotkb:MSG1(gene name synonym)	psi-mi:sc23b_human(display_long)|uniprotkb:SEC23-related protein B(gene name synonym)|uniprotkb:SEC23B(gene name)|psi-mi:SEC23B(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551704|imex:IM-24995-3497	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012955.1|sgd:S000001738|mint:P36125|dip:DIP-2023N|ensemblfungi:YKR030W(gene)|ensemblfungi:YKR030W_mRNA(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030173"(integral component of Golgi membrane)|interpro:IPR007881(UNC-50)	refseq:NP_001166216.1|refseq:NP_006354.2|refseq:NP_116780.1|refseq:NP_116781.1|ensembl:ENSG00000101310(gene)|ensembl:ENST00000262544(transcript)|ensembl:ENST00000336714(transcript)|ensembl:ENST00000377465(transcript)|ensembl:ENST00000650089(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008270"(zinc ion binding)|go:"GO:0012505"(endomembrane system)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0090110"(COPII-coated vesicle cargo loading)|go:"GO:0070971"(endoplasmic reticulum exit site)|interpro:IPR006895(Zinc finger, Sec23/Sec24-type)|interpro:IPR006896(Sec23/Sec24 trunk region)|interpro:IPR006900(Sec23/Sec24 helical region)|interpro:IPR007123(Gelsolin region)|interpro:IPR012990(Sec23/Sec24 beta-sandwich)|interpro:IPR029006|interpro:IPR036174|interpro:IPR036175|interpro:IPR036180|interpro:IPR036465|interpro:IPR037364|interpro:IPR037550|mint:Q15437|refseq:XP_016883082.1	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:lmgeWk7CkMQRDAfkDOgwqC9rb/g559292	rogid:+3KZ/1jjziSgJRcr81Axquofkl49606	intact-crc:B197227D7733D90E|rigid:DPf4M4oTuC9pt++S4M+AuOcy+zA	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P38166	uniprotkb:Q15437	intact:EBI-17046|uniprotkb:D6VPQ1|ensemblfungi:YBL102W	intact:EBI-742673|uniprotkb:Q5W183|uniprotkb:Q9BS15|uniprotkb:Q9BSI2|uniprotkb:Q9H1D7|intact:EBI-1048165|uniprotkb:Q503A9|uniprotkb:D3DW33|ensembl:ENSP00000262544|ensembl:ENSP00000338844|ensembl:ENSP00000366685|ensembl:ENSP00000497473	psi-mi:sft2_yeast(display_long)|uniprotkb:YBL0812(orf name)|uniprotkb:YBL102W(locus name)|uniprotkb:SFT2(gene name)|psi-mi:SFT2(display_short)	psi-mi:sc23b_human(display_long)|uniprotkb:SEC23-related protein B(gene name synonym)|uniprotkb:SEC23B(gene name)|psi-mi:SEC23B(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551708|imex:IM-24995-3498	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YBL102W(gene)|ensemblfungi:YBL102W_mRNA(transcript)|go:"GO:0000138"(Golgi trans cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005829"(cytosol)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|interpro:IPR007305(Got1-like protein)|interpro:IPR011691(SFT2-like)|refseq:NP_009448.1|sgd:S000000198|dip:DIP-1865N|mint:P38166	refseq:NP_001166216.1|refseq:NP_006354.2|refseq:NP_116780.1|refseq:NP_116781.1|ensembl:ENSG00000101310(gene)|ensembl:ENST00000262544(transcript)|ensembl:ENST00000336714(transcript)|ensembl:ENST00000377465(transcript)|ensembl:ENST00000650089(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008270"(zinc ion binding)|go:"GO:0012505"(endomembrane system)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0090110"(COPII-coated vesicle cargo loading)|go:"GO:0070971"(endoplasmic reticulum exit site)|interpro:IPR006895(Zinc finger, Sec23/Sec24-type)|interpro:IPR006896(Sec23/Sec24 trunk region)|interpro:IPR006900(Sec23/Sec24 helical region)|interpro:IPR007123(Gelsolin region)|interpro:IPR012990(Sec23/Sec24 beta-sandwich)|interpro:IPR029006|interpro:IPR036174|interpro:IPR036175|interpro:IPR036180|interpro:IPR036465|interpro:IPR037364|interpro:IPR037550|mint:Q15437|refseq:XP_016883082.1	-	crc64:1BF971749814382C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:tGTSgSqEOsu/4dXIp31UzvtkyKs559292	rogid:+3KZ/1jjziSgJRcr81Axquofkl49606	intact-crc:B467DC84F57D0B83|rigid:s/Px0A+1Hb5Mw2Fxv5DKdhsoRtA	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P39724	uniprotkb:Q15654	intact:EBI-2343154|uniprotkb:D6VPH0|ensemblfungi:YAL046C	intact:EBI-742327|uniprotkb:O15170|uniprotkb:O15275|uniprotkb:Q9BTB2|uniprotkb:Q9BUE5|uniprotkb:Q9BXP3|uniprotkb:Q9UNT4|uniprotkb:A4D2E7|ensembl:ENSP00000200457|uniprotkb:F2ZC07|uniprotkb:F2ZC08	psi-mi:bol3_yeast(display_long)|uniprotkb:BOL3(gene name)|psi-mi:BOL3(display_short)|uniprotkb:AIM1(gene name synonym)|uniprotkb:Altered inheritance of mitochondria protein 1(gene name synonym)|uniprotkb:YAL046C(locus name)	psi-mi:trip6_human(display_long)|uniprotkb:TRIP6(gene name)|psi-mi:TRIP6(display_short)|uniprotkb:OIP1(gene name synonym)|uniprotkb:Opa-interacting protein 1(gene name synonym)|uniprotkb:Zyxin-related protein 1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551732|imex:IM-24995-3504	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009353.1|sgd:S000000044|interpro:IPR002634(BolA-like protein)|interpro:IPR036065|mint:P39724|ensemblfungi:YAL046C(gene)|ensemblfungi:YAL046C_mRNA(transcript)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0106035"(protein maturation by [4Fe-4S] cluster transfer)	refseq:NP_003293.2|ensembl:ENSP00000200457|ensembl:ENST00000417475|ensembl:ENSP00000413817|ensembl:ENST00000437505|ensembl:ENSP00000410736|ensembl:ENST00000619988|ensembl:ENSP00000479865|ensembl:ENSG00000087077(gene)|ensembl:ENST00000200457(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003723"(RNA binding)|go:"GO:0005149"(interleukin-1 receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0019900"(kinase binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0043009"(chordate embryonic development)|go:"GO:0046872"(metal ion binding)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|interpro:IPR001781(Zinc finger, LIM-type)|mint:Q15654|rcsb pdb:1X61|rcsb pdb:2DLO|dip:DIP-34466N	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:MLrW6Iu4YKXf87O1cyx5bY03VdE559292	rogid:9Okf3b6sMMwX5awAx991GN9iSsQ9606	intact-crc:0D3D375579514FBF|rigid:DQ5th5VfoAYEXx1mb5UxyiScCQI	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q15654	uniprotkb:P38263	intact:EBI-742327|uniprotkb:O15170|uniprotkb:O15275|uniprotkb:Q9BTB2|uniprotkb:Q9BUE5|uniprotkb:Q9BXP3|uniprotkb:Q9UNT4|uniprotkb:A4D2E7|ensembl:ENSP00000200457|uniprotkb:F2ZC07|uniprotkb:F2ZC08	intact:EBI-20304|uniprotkb:D6VQA4|ensemblfungi:YBR105C	psi-mi:trip6_human(display_long)|uniprotkb:TRIP6(gene name)|psi-mi:TRIP6(display_short)|uniprotkb:OIP1(gene name synonym)|uniprotkb:Opa-interacting protein 1(gene name synonym)|uniprotkb:Zyxin-related protein 1(gene name synonym)	psi-mi:gid4_yeast(display_long)|uniprotkb:VID24(gene name)|psi-mi:VID24(display_short)|uniprotkb:YBR105C(locus name)|uniprotkb:YBR0834(orf name)|uniprotkb:GID4(gene name synonym)|uniprotkb:Glucose-induced degradation protein 4(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551728|imex:IM-24995-3503	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003293.2|ensembl:ENSP00000200457|ensembl:ENST00000417475|ensembl:ENSP00000413817|ensembl:ENST00000437505|ensembl:ENSP00000410736|ensembl:ENST00000619988|ensembl:ENSP00000479865|ensembl:ENSG00000087077(gene)|ensembl:ENST00000200457(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003723"(RNA binding)|go:"GO:0005149"(interleukin-1 receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0019900"(kinase binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0043009"(chordate embryonic development)|go:"GO:0046872"(metal ion binding)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|interpro:IPR001781(Zinc finger, LIM-type)|mint:Q15654|rcsb pdb:1X61|rcsb pdb:2DLO|dip:DIP-34466N	refseq:NP_009663.1|sgd:S000000309|ensemblfungi:YBR105C(gene)|ensemblfungi:YBR105C_mRNA(transcript)|go:"GO:0005773"(vacuole)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0007039"(protein catabolic process in the vacuole)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034657"(GID complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045721"(negative regulation of gluconeogenesis)|go:"GO:0071596"(ubiquitin-dependent protein catabolic process via the N-end rule pathway)|interpro:IPR018618|rcsb pdb:6SWY|dip:DIP-4502N|mint:P38263	-	-	crc64:FF020B239676E0B2	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:9Okf3b6sMMwX5awAx991GN9iSsQ9606	rogid:ag6caXMIP/qIv27yJtSEmlBoI7g559292	intact-crc:D1BEF544615FDFFF|rigid:xb2A35dOA0wawIH6nclhVdXnXro	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q15645	uniprotkb:Q04307	intact:EBI-358993|uniprotkb:C9K0T3|uniprotkb:O15324|ensembl:ENSP00000166345|uniprotkb:D3DTC0	intact:EBI-15858|uniprotkb:Q2VQW5|ensemblfungi:YDR045C|uniprotkb:D6VS33	psi-mi:pch2_human(display_long)|uniprotkb:TRIP13(gene name)|psi-mi:TRIP13(display_short)|uniprotkb:Thyroid receptor-interacting protein 13(gene name synonym)|uniprotkb:PCH2(gene name synonym)|uniprotkb:Thyroid hormone receptor interactor 13(gene name synonym)|uniprotkb:Human papillomavirus type 16 E1 protein-binding protein(gene name synonym)	psi-mi:rpc10_yeast(display_long)|uniprotkb:RPC11(gene name)|psi-mi:RPC11(display_short)|uniprotkb:YDR045C(locus name)|uniprotkb:YD9609.01C(orf name)|uniprotkb:RNA polymerase III subunit C11(gene name synonym)|uniprotkb:DNA-directed RNA polymerases III 12.5 kDa polypeptide(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551716|imex:IM-24995-3500	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004228.1|ensembl:ENSG00000071539(gene)|ensembl:ENST00000166345(transcript)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|refseq:XP_011512465.1|dip:DIP-34493N|go:"GO:0005694"(chromosome)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0007141"(male meiosis I)|go:"GO:0007144"(female meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007286"(spermatid development)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051598"(meiotic recombination checkpoint signaling)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR027417|interpro:IPR044539|mint:Q15645|rcsb pdb:5VQ9|rcsb pdb:5VQA|rcsb pdb:5WC2|rcsb pdb:6F0X|rcsb pdb:6LK0|rcsb pdb:7L9P	ensemblfungi:YDR045C(gene)|refseq:NP_010330.1|sgd:S000002452|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006386"(termination of RNA polymerase III transcription)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042779"(tRNA 3'-trailer cleavage)|go:"GO:0042797"(tRNA transcription by RNA polymerase III)|interpro:IPR001222(Zinc finger, TFIIS-type)|interpro:IPR001529(DNA-directed RNA polymerase, M/15 kDa subunit)|interpro:IPR012164(DNA-directed RNA polymerase, subunit C11/M/9)|interpro:IPR019761|interpro:IPR034014|rcsb pdb:3QT1|ensemblfungi:YDR045C_mRNA(transcript)|rcsb pdb:5FJ8|rcsb pdb:5FJ9|rcsb pdb:5FJA|rcsb pdb:6CNB|rcsb pdb:6CNC|rcsb pdb:6CND|rcsb pdb:6CNF|rcsb pdb:6EU0|rcsb pdb:6EU2|rcsb pdb:6EU3|rcsb pdb:6F40|rcsb pdb:6F41|rcsb pdb:6F42|rcsb pdb:6F44|rcsb pdb:6TUT|reactome:R-SCE-76061|reactome:R-SCE-76066|rcsb pdb:6EU1|dip:DIP-887N|mint:Q04307	-	-	crc64:E4AA802EC9F92230	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:heF2f3R2lGIpZ80mZHnhMktXTE49606	rogid:G2fIQbptabHIUI224iPtTJF+dIs559292	intact-crc:2D977C277830FFBD|rigid:xjGEbc9I5sNUM3H74oZtdRfa8/k	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P40446	uniprotkb:Q15645	intact:EBI-11530862|uniprotkb:D6VVC2|uniprotkb:Q05730|ensemblfungi:YIL165C	intact:EBI-358993|uniprotkb:C9K0T3|uniprotkb:O15324|ensembl:ENSP00000166345|uniprotkb:D3DTC0	psi-mi:yiq5_yeast(display_long)|uniprotkb:YI9402.10AC(orf name)|uniprotkb:YIL165C(locus name)	psi-mi:pch2_human(display_long)|uniprotkb:TRIP13(gene name)|psi-mi:TRIP13(display_short)|uniprotkb:Thyroid receptor-interacting protein 13(gene name synonym)|uniprotkb:PCH2(gene name synonym)|uniprotkb:Thyroid hormone receptor interactor 13(gene name synonym)|uniprotkb:Human papillomavirus type 16 E1 protein-binding protein(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551720|imex:IM-24995-3501	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR003010(Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase)|refseq:NP_012101.1|sgd:S000001427|interpro:IPR044149|ensemblfungi:YIL165C(gene)|ensemblfungi:YIL165C_mRNA(transcript)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0003824"(catalytic activity)|go:"GO:0006807"(nitrogen compound metabolic process)|go:"GO:0016236"(macroautophagy)|interpro:IPR036526	refseq:NP_004228.1|ensembl:ENSG00000071539(gene)|ensembl:ENST00000166345(transcript)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|refseq:XP_011512465.1|dip:DIP-34493N|go:"GO:0005694"(chromosome)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0007141"(male meiosis I)|go:"GO:0007144"(female meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007286"(spermatid development)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051598"(meiotic recombination checkpoint signaling)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR027417|interpro:IPR044539|mint:Q15645|rcsb pdb:5VQ9|rcsb pdb:5VQA|rcsb pdb:5WC2|rcsb pdb:6F0X|rcsb pdb:6LK0|rcsb pdb:7L9P	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/03/16	rogid:5G/EX7rlenWVlKfGQdYrkSF26Lw559292	rogid:heF2f3R2lGIpZ80mZHnhMktXTE49606	intact-crc:301514A01D27C2E1|rigid:tQ+Lq4y8f+dGePQC1yTsxnbJor4	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q15645	uniprotkb:P00330	intact:EBI-358993|uniprotkb:C9K0T3|uniprotkb:O15324|ensembl:ENSP00000166345|uniprotkb:D3DTC0	intact:EBI-2218|uniprotkb:D6W1Y3|ensemblfungi:YOL086C	psi-mi:pch2_human(display_long)|uniprotkb:TRIP13(gene name)|psi-mi:TRIP13(display_short)|uniprotkb:Thyroid receptor-interacting protein 13(gene name synonym)|uniprotkb:PCH2(gene name synonym)|uniprotkb:Thyroid hormone receptor interactor 13(gene name synonym)|uniprotkb:Human papillomavirus type 16 E1 protein-binding protein(gene name synonym)	psi-mi:adh1_yeast(display_long)|uniprotkb:ADH1(gene name)|psi-mi:ADH1(display_short)|uniprotkb:ADC1(gene name synonym)|uniprotkb:YOL086C(locus name)|uniprotkb:O0947(orf name)|uniprotkb:Alcohol dehydrogenase I(gene name synonym)|uniprotkb:YADH-1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551724|imex:IM-24995-3502	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004228.1|ensembl:ENSG00000071539(gene)|ensembl:ENST00000166345(transcript)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|refseq:XP_011512465.1|dip:DIP-34493N|go:"GO:0005694"(chromosome)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0007141"(male meiosis I)|go:"GO:0007144"(female meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007286"(spermatid development)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051598"(meiotic recombination checkpoint signaling)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR027417|interpro:IPR044539|mint:Q15645|rcsb pdb:5VQ9|rcsb pdb:5VQA|rcsb pdb:5WC2|rcsb pdb:6F0X|rcsb pdb:6LK0|rcsb pdb:7L9P	refseq:NP_014555.1|sgd:S000005446|dip:DIP-1143N|mint:P00330|ensemblfungi:YOL086C(gene)|ensemblfungi:YOL086C_mRNA(transcript)|go:"GO:0000947"(amino acid catabolic process to alcohol via Ehrlich pathway)|go:"GO:0004022"("alcohol dehydrogenase (NAD+) activity")|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006116"(NADH oxidation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019170"("methylglyoxal reductase (NADH-dependent) activity")|go:"GO:0042802"(identical protein binding)|go:"GO:0043458"(ethanol biosynthetic process involved in glucose fermentation to ethanol)|go:"GO:0045069"(regulation of viral genome replication)|go:"GO:0046809"(replication compartment)|go:"GO:1904408"(melatonin binding)|interpro:IPR002328(Alcohol dehydrogenase, zinc-containing, conserved site)|interpro:IPR011032(GroES-like)|interpro:IPR013149(Alcohol dehydrogenase, zinc-binding)|interpro:IPR013154(Alcohol dehydrogenase GroES-like)|interpro:IPR020843|interpro:IPR036291|rcsb pdb:4W6Z|rcsb pdb:5ENV	-	-	crc64:F14AE24B5D8D12A5	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:heF2f3R2lGIpZ80mZHnhMktXTE49606	rogid:ud0TIPDwB9vm9Ug9a5a4wY20oZ8559292	intact-crc:9126E6F50CD07291|rigid:84bDhYeVJEiw569dEKt/iNyltFs	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P25372	uniprotkb:Q15654	intact:EBI-19616|uniprotkb:D6VR84|ensemblfungi:YCR083W	intact:EBI-742327|uniprotkb:O15170|uniprotkb:O15275|uniprotkb:Q9BTB2|uniprotkb:Q9BUE5|uniprotkb:Q9BXP3|uniprotkb:Q9UNT4|uniprotkb:A4D2E7|ensembl:ENSP00000200457|uniprotkb:F2ZC07|uniprotkb:F2ZC08	psi-mi:trx3_yeast(display_long)|uniprotkb:TRX3(gene name)|psi-mi:TRX3(display_short)|uniprotkb:YCR83W(orf name)|uniprotkb:YCR083W(locus name)	psi-mi:trip6_human(display_long)|uniprotkb:TRIP6(gene name)|psi-mi:TRIP6(display_short)|uniprotkb:OIP1(gene name synonym)|uniprotkb:Opa-interacting protein 1(gene name synonym)|uniprotkb:Zyxin-related protein 1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551736|imex:IM-24995-3505	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR036249|refseq:NP_010006.1|sgd:S000000679|interpro:IPR017937|interpro:IPR013766(Thioredoxin domain)|rcsb pdb:2OE0|rcsb pdb:2OE1|rcsb pdb:2OE3|ensemblfungi:YCR083W(gene)|ensemblfungi:YCR083W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0015036"(disulfide oxidoreductase activity)|go:"GO:0034599"(cellular response to oxidative stress)|rcsb pdb:5YKW	refseq:NP_003293.2|ensembl:ENSP00000200457|ensembl:ENST00000417475|ensembl:ENSP00000413817|ensembl:ENST00000437505|ensembl:ENSP00000410736|ensembl:ENST00000619988|ensembl:ENSP00000479865|ensembl:ENSG00000087077(gene)|ensembl:ENST00000200457(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003723"(RNA binding)|go:"GO:0005149"(interleukin-1 receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0019900"(kinase binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0043009"(chordate embryonic development)|go:"GO:0046872"(metal ion binding)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|interpro:IPR001781(Zinc finger, LIM-type)|mint:Q15654|rcsb pdb:1X61|rcsb pdb:2DLO|dip:DIP-34466N	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:g0xjGf9GvJRl8iv2qoT5tOs7jXI559292	rogid:9Okf3b6sMMwX5awAx991GN9iSsQ9606	intact-crc:D27F0CD995DEDACB|rigid:LQ5IHqe2DXnYjM69+r3vayu38eE	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P47041	uniprotkb:Q15654	intact:EBI-25889|uniprotkb:D6VWC4|ensemblfungi:YJL058C	intact:EBI-742327|uniprotkb:O15170|uniprotkb:O15275|uniprotkb:Q9BTB2|uniprotkb:Q9BUE5|uniprotkb:Q9BXP3|uniprotkb:Q9UNT4|uniprotkb:A4D2E7|ensembl:ENSP00000200457|uniprotkb:F2ZC07|uniprotkb:F2ZC08	psi-mi:bit61_yeast(display_long)|uniprotkb:YJL058C(locus name)|uniprotkb:J1141(orf name)|uniprotkb:61 kDa binding partner of TOR2 protein(gene name synonym)|uniprotkb:BIT61(gene name)|psi-mi:BIT61(display_short)	psi-mi:trip6_human(display_long)|uniprotkb:TRIP6(gene name)|psi-mi:TRIP6(display_short)|uniprotkb:OIP1(gene name synonym)|uniprotkb:Opa-interacting protein 1(gene name synonym)|uniprotkb:Zyxin-related protein 1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551740|imex:IM-24995-3506	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012477.1|sgd:S000003594|dip:DIP-1444N|reactome:R-SCE-1257604|reactome:R-SCE-389357|reactome:R-SCE-5218920|ensemblfungi:YJL058C(gene)|ensemblfungi:YJL058C_mRNA(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005737"(cytoplasm)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0031932"(TORC2 complex)|go:"GO:0038203"(TORC2 signaling)|go:"GO:0071944"(cell periphery)|interpro:IPR013745(HbrB-like)|reactome:R-SCE-6804757	refseq:NP_003293.2|ensembl:ENSP00000200457|ensembl:ENST00000417475|ensembl:ENSP00000413817|ensembl:ENST00000437505|ensembl:ENSP00000410736|ensembl:ENST00000619988|ensembl:ENSP00000479865|ensembl:ENSG00000087077(gene)|ensembl:ENST00000200457(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003723"(RNA binding)|go:"GO:0005149"(interleukin-1 receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0019900"(kinase binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0043009"(chordate embryonic development)|go:"GO:0046872"(metal ion binding)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|interpro:IPR001781(Zinc finger, LIM-type)|mint:Q15654|rcsb pdb:1X61|rcsb pdb:2DLO|dip:DIP-34466N	-	crc64:99F0F96840311F4B	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:H+zcKwbWL90wsmvD9TfWYmEbRwM559292	rogid:9Okf3b6sMMwX5awAx991GN9iSsQ9606	intact-crc:81FBAAF545136BBB|rigid:TfpCjtS5+M2jhCdi2e0hjGITtNk	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q15834	uniprotkb:O13539	intact:EBI-739674|uniprotkb:Q96HA0|uniprotkb:B2R598|ensembl:ENSP00000311695	intact:EBI-30898|uniprotkb:D3DLB6|ensemblfungi:YHR167W	psi-mi:cc85b_human(display_long)|uniprotkb:CCDC85B(gene name)|psi-mi:CCDC85B(display_short)|uniprotkb:Hepatitis delta antigen-interacting protein A(gene name synonym)|uniprotkb:DIPA(gene name synonym)	psi-mi:thp2_yeast(display_long)|uniprotkb:THP2(gene name)|psi-mi:THP2(display_short)|uniprotkb:YHR167W(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551744|imex:IM-24995-3507	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006839.2|ensembl:ENSG00000175602(gene)|ensembl:ENST00000312579(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005912"(adherens junction)|go:"GO:0030154"(cell differentiation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0070097"(delta-catenin binding)|interpro:IPR019359	refseq:NP_012037.1|sgd:S000001210|dip:DIP-4246N|mint:O13539|ensemblfungi:YHR167W(gene)|ensemblfungi:YHR167W_mRNA(transcript)|go:"GO:0000445"(THO complex part of transcription export complex)|go:"GO:0000446"(nucleoplasmic THO complex)|go:"GO:0000723"(telomere maintenance)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0006310"(DNA recombination)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0034063"(stress granule assembly)|interpro:IPR018557|rcsb pdb:7APX|rcsb pdb:7LUV	-	-	crc64:16EFA6F464507C57	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:DUMY8gDRLRjC4Iu+z7SVBZ6sQkY9606	rogid:SaTSL6jLwX1hTVCqvU8ZNR96r8U559292	intact-crc:DF6C091E9259CF4F|rigid:P/TDjEqBpyXpQmTQQPkNo6/Nytc	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q12318	uniprotkb:Q15911-2	intact:EBI-37340|uniprotkb:D6VZ12|ensemblfungi:YLR376C	intact:EBI-10237226|ensembl:ENSP00000438926	psi-mi:psy3_yeast(display_long)|uniprotkb:PSY3(gene name)|psi-mi:PSY3(display_short)|uniprotkb:L8039.17(orf name)|uniprotkb:YLR376C(locus name)	psi-mi:q15911-2(display_long)|uniprotkb:ZFHX3(gene name)|psi-mi:ZFHX3(display_short)|uniprotkb:AT motif-binding factor 1(gene name synonym)|uniprotkb:AT-binding transcription factor 1(gene name synonym)|uniprotkb:ATBF1(gene name synonym)|uniprotkb:Alpha-fetoprotein enhancer-binding protein(gene name synonym)|uniprotkb:Zinc finger homeodomain protein 3(gene name synonym)|uniprotkb:C16orf47(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551748|imex:IM-24995-3508	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000004368|refseq:NP_013480.1|dip:DIP-1903N|ensemblfungi:YLR376C(gene)|ensemblfungi:YLR376C_mRNA(transcript)|go:"GO:0000725"(recombinational repair)|go:"GO:0000730"(DNA recombinase assembly)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0035861"(site of double-strand break)|go:"GO:0070987"(error-free translesion synthesis)|go:"GO:0097196"(Shu complex)|interpro:IPR027417|interpro:IPR031779|rcsb pdb:3VU9|rcsb pdb:4DT1|rcsb pdb:4EQ6|rcsb pdb:5XYN	intact:EBI-2849611(isoform-parent)|uniprotkb:Q15911-2(isoform-parent)|ensembl:ENST00000397992(transcript)|ensembl:ENSG00000140836(gene)	-	crc64:B652FD8113EB4C12	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:SlNKYcljv2UVV8YxX5/kVQJV/rU559292	rogid:2SwbWXRFfxKEHEbo/SlMGw8/hPU9606	intact-crc:83EEE11223C0AC8B|rigid:lt0Ppo9sfiGTtecbUmGmPV8ZC3U	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P33299	uniprotkb:Q16401	intact:EBI-13910|uniprotkb:D6VX51|ensemblfungi:YKL145W	intact:EBI-752143|uniprotkb:Q15045|uniprotkb:Q4VXG8|intact:EBI-10968906|uniprotkb:B4DZM8|ensembl:ENSP00000210313	psi-mi:prs7_yeast(display_long)|uniprotkb:YKL145W(locus name)|uniprotkb:RPT1(gene name)|psi-mi:RPT1(display_short)|uniprotkb:CIM5(gene name synonym)|uniprotkb:YTA3(gene name synonym)|uniprotkb:Protein CIM5(gene name synonym)|uniprotkb:Tat-binding homolog 3(gene name synonym)	psi-mi:psmd5_human(display_long)|uniprotkb:26S proteasome subunit S5B(gene name synonym)|uniprotkb:26S protease subunit S5 basic(gene name synonym)|uniprotkb:PSMD5(gene name)|psi-mi:PSMD5(display_short)|uniprotkb:KIAA0072(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551752|imex:IM-24995-3509	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012777.1|sgd:S000001628|ensemblfungi:YKL145W(gene)|go:"GO:0070682"(proteasome regulatory particle assembly)|interpro:IPR003593(AAA+ ATPase, core)|ensemblfungi:YKL145W_mRNA(transcript)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|go:"GO:0005524"(ATP binding)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR035245|interpro:IPR041569|rcsb pdb:3JCO|rcsb pdb:3JCP|go:"GO:0005634"(nucleus)|rcsb pdb:3VLF|rcsb pdb:4A3V|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:4JPO|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|rcsb pdb:5A5B|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|rcsb pdb:5MP9|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0045732"(positive regulation of protein catabolic process)|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-6798695|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|rcsb pdb:6EF3|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|mint:P33299|dip:DIP-2883N	refseq:NP_005038.1|refseq:NP_001257356.1|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|ensembl:ENSG00000095261(gene)|ensembl:ENST00000210313(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0070682"(proteasome regulatory particle assembly)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR019538|mint:Q16401|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556	-	crc64:8454BBC9D549EC5C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:8XXo53yZ1KevHObtYWABeFr0hWo559292	rogid:XLVvCeWct98fvc6ktvaWNXwt9dE9606	intact-crc:672A14D428CC7998|rigid:I7TUR8lYODCxwSY3l1utKDnZ0a8	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q16630-2	uniprotkb:P20081	intact:EBI-11088043|ensembl:ENSP00000266679	intact:EBI-6961|uniprotkb:D6W147|ensemblfungi:YNL135C	psi-mi:q16630-2(display_long)|uniprotkb:CPSF6(gene name)|psi-mi:CPSF6(display_short)|uniprotkb:CFIM68(gene name synonym)|uniprotkb:Cleavage and polyadenylation specificity factor 68 kDa subunit(gene name synonym)|uniprotkb:Pre-mRNA cleavage factor Im 68 kDa subunit(gene name synonym)|uniprotkb:Protein HPBRII-4/7(gene name synonym)|uniprotkb:Cleavage factor Im complex 68 kDa subunit(gene name synonym)	psi-mi:fkbp_yeast(display_long)|uniprotkb:RBP1(gene name synonym)|uniprotkb:N1213(orf name)|uniprotkb:N1845(orf name)|uniprotkb:YNL135C(locus name)|uniprotkb:FPR1(gene name)|psi-mi:FPR1(display_short)|uniprotkb:FKB1(gene name synonym)|uniprotkb:Peptidyl-prolyl cis-trans isomerase(gene name synonym)|uniprotkb:Rapamycin-binding protein(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551756|imex:IM-24995-3510	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-358410(isoform-parent)|ensembl:ENSG00000111605(gene)|ensembl:ENST00000266679(transcript)|uniprotkb:Q16630-2(isoform-parent)	refseq:NP_014264.1|sgd:S000005079|dip:DIP-1263N|mint:P20081|ensemblfungi:YNL135C(gene)|ensemblfungi:YNL135C_mRNA(transcript)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005527"(macrolide binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006325"(chromatin organization)|go:"GO:0006457"(protein folding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:1901710"(regulation of homoserine biosynthetic process)|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)|rcsb pdb:1YAT	-	-	crc64:65C134830D300C06	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:y66l9ctsSYs6fhxdYD5CJ0cDZFA9606	rogid:8afvGSk+mPghtqkVoWd2rHJXXhQ559292	intact-crc:01A2BFE9E777877B|rigid:tJHZJQq9S7vVqWv1C+ntEmixQd8	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P20081	uniprotkb:Q16630-3	intact:EBI-6961|uniprotkb:D6W147|ensemblfungi:YNL135C	intact:EBI-11523850	psi-mi:fkbp_yeast(display_long)|uniprotkb:RBP1(gene name synonym)|uniprotkb:N1213(orf name)|uniprotkb:N1845(orf name)|uniprotkb:YNL135C(locus name)|uniprotkb:FPR1(gene name)|psi-mi:FPR1(display_short)|uniprotkb:FKB1(gene name synonym)|uniprotkb:Peptidyl-prolyl cis-trans isomerase(gene name synonym)|uniprotkb:Rapamycin-binding protein(gene name synonym)	psi-mi:q16630-3(display_long)|uniprotkb:CFIM68(gene name synonym)|uniprotkb:Cleavage and polyadenylation specificity factor 68 kDa subunit(gene name synonym)|uniprotkb:Pre-mRNA cleavage factor Im 68 kDa subunit(gene name synonym)|uniprotkb:Protein HPBRII-4/7(gene name synonym)|uniprotkb:CPSF6(gene name)|psi-mi:CPSF6(display_short)|uniprotkb:Cleavage factor Im complex 68 kDa subunit(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551760|imex:IM-24995-3511	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014264.1|sgd:S000005079|dip:DIP-1263N|mint:P20081|ensemblfungi:YNL135C(gene)|ensemblfungi:YNL135C_mRNA(transcript)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005527"(macrolide binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006325"(chromatin organization)|go:"GO:0006457"(protein folding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:1901710"(regulation of homoserine biosynthetic process)|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)|rcsb pdb:1YAT	intact:EBI-358410(isoform-parent)	-	crc64:65C134830D300C06	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:8afvGSk+mPghtqkVoWd2rHJXXhQ559292	rogid:diwzHQNNZ4fMHYzs292gLpdKfE09606	intact-crc:B1AC0EE4252DF2DC|rigid:MYZyptYN7WodpKxm8QFAfiQIfvE	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q16637	uniprotkb:Q12460	intact:EBI-395421|uniprotkb:Q13119|uniprotkb:Q549U5|uniprotkb:Q96J51|ensembl:ENSP00000305857|uniprotkb:A8K0V4|ensembl:ENSP00000370083|ensembl:ENSP00000370117|ensembl:ENSP00000370119|ensembl:ENSP00000479920|ensembl:ENSP00000482966|ensembl:ENSP00000483515|ensembl:ENSP00000483819|ensembl:ENSP00000487206|ensembl:ENSP00000487421	intact:EBI-17148|ensemblfungi:YLR197W|uniprotkb:D6VYK0	psi-mi:smn_human(display_long)|uniprotkb:SMN1(gene name)|psi-mi:SMN1(display_short)|uniprotkb:SMN(gene name synonym)|uniprotkb:SMNT(gene name synonym)|uniprotkb:SMN2(gene name)|psi-mi:SMN2(display_short)|uniprotkb:SMNC(gene name synonym)|uniprotkb:Component of gems 1(gene name synonym)|uniprotkb:Gemin-1(gene name synonym)	psi-mi:nop56_yeast(display_long)|uniprotkb:SIK1(gene name synonym)|uniprotkb:Ribosome biosynthesis protein SIK1(gene name synonym)|uniprotkb:YLR197W(locus name)|uniprotkb:L8167.9(orf name)|uniprotkb:NOP56(gene name)|psi-mi:NOP56(display_short)|uniprotkb:Suppressor of I kappa b protein 1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551764|imex:IM-24995-3512	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000335.1|refseq:NP_059107.1|refseq:NP_075012.1|refseq:NP_075013.1|refseq:NP_075014.1|refseq:NP_075015.1|ensembl:ENSG00000172062(gene)|ensembl:ENSG00000205571(gene)|ensembl:ENSG00000273772(gene)|ensembl:ENSG00000275349(gene)|ensembl:ENSG00000277773(gene)|ensembl:ENST00000351205(transcript)|ensembl:ENST00000380707(transcript)|ensembl:ENST00000380741(transcript)|ensembl:ENST00000380743(transcript)|ensembl:ENST00000614610(transcript)|ensembl:ENST00000618251(transcript)|ensembl:ENST00000618661(transcript)|ensembl:ENST00000622739(transcript)|ensembl:ENST00000627341(transcript)|ensembl:ENST00000629122(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0007399"(nervous system development)|go:"GO:0015030"(Cajal body)|go:"GO:0016604"(nuclear body)|go:"GO:0030018"(Z disc)|go:"GO:0030424"(axon)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043204"(perikaryon)|go:"GO:0097504"(Gemini of coiled bodies)|interpro:IPR002999(Tudor)|interpro:IPR010304(Survival motor neuron)|mint:Q16637|rcsb pdb:1G5V|rcsb pdb:1MHN|rcsb pdb:2LEH|rcsb pdb:4A4E|rcsb pdb:4A4G|rcsb pdb:4GLI|rcsb pdb:4QQ6|rcsb pdb:5XJL|go:"GO:0034719"(SMN-Sm protein complex)|rcsb pdb:5XJQ|rcsb pdb:5XJR|rcsb pdb:5XJS|rcsb pdb:5XJT|rcsb pdb:5XJU|reactome:R-HSA-191859|go:"GO:0032797"(SMN complex)|refseq:NP_001284644.1|ensembl:ENSP00000305857|ensembl:ENSP00000370083|ensembl:ENSP00000370117|ensembl:ENST00000380742|ensembl:ENSP00000370118|ensembl:ENSP00000370119|ensembl:ENST00000503079|ensembl:ENSP00000428128|ensembl:ENST00000506163|ensembl:ENSP00000424926|ensembl:ENST00000611442|ensembl:ENSP00000483768|ensembl:ENST00000614240|ensembl:ENSP00000479279|ensembl:ENSP00000479920|ensembl:ENST00000614773|ensembl:ENSP00000481427|ensembl:ENSP00000483515|ensembl:ENSP00000483819|ensembl:ENST00000622158|ensembl:ENSP00000480906|ensembl:ENSP00000482966|ensembl:ENST00000624634|ensembl:ENSP00000485595|ensembl:ENST00000626847|ensembl:ENSP00000486152|ensembl:ENSP00000487421|ensembl:ENST00000628353|ensembl:ENSP00000487029|ensembl:ENST00000628642|ensembl:ENSP00000487015|ensembl:ENSP00000487206|refseq:XP_016865275.1|dip:DIP-31309N	ensemblfungi:YLR197W(gene)|ensemblfungi:YLR197W_mRNA(transcript)|go:"GO:0000154"(rRNA modification)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|refseq:NP_013298.1|sgd:S000004187|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0030515"(snoRNA binding)|go:"GO:0030686"(90S preribosome)|go:"GO:0031428"(box C/D RNP complex)|go:"GO:0032040"(small-subunit processome)|interpro:IPR002687(Pre-mRNA processing ribonucleoprotein, binding region)|interpro:IPR012974(NOP5, N-terminal)|interpro:IPR012976(NOSIC)|interpro:IPR036070|interpro:IPR042239|rcsb pdb:5WLC|rcsb pdb:5WYJ|rcsb pdb:5WYK|rcsb pdb:6KE6|rcsb pdb:6LQP|rcsb pdb:6LQQ|rcsb pdb:6LQR|rcsb pdb:6LQS|rcsb pdb:6LQT|rcsb pdb:6LQU|rcsb pdb:6LQV|rcsb pdb:6ND4|rcsb pdb:6ZDT|rcsb pdb:6ZQA|rcsb pdb:6ZQB|rcsb pdb:6ZQC|rcsb pdb:6ZQD|rcsb pdb:6ZQE|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-6791226|dip:DIP-4405N|mint:Q12460	-	-	crc64:F8522A5870EF4842	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:QGivm7E8suciCWXO4l0zCUzCl2g9606	rogid:l3UAmoOUECH1uov6nv7MSwSv/3s559292	intact-crc:EA133C39F0FBB082|rigid:P7RgU+Kz+2UAHNUypIgPhi0aL0o	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q16637	uniprotkb:P15646	intact:EBI-395421|uniprotkb:Q13119|uniprotkb:Q549U5|uniprotkb:Q96J51|ensembl:ENSP00000305857|uniprotkb:A8K0V4|ensembl:ENSP00000370083|ensembl:ENSP00000370117|ensembl:ENSP00000370119|ensembl:ENSP00000479920|ensembl:ENSP00000482966|ensembl:ENSP00000483515|ensembl:ENSP00000483819|ensembl:ENSP00000487206|ensembl:ENSP00000487421	intact:EBI-6838|uniprotkb:P89890|uniprotkb:D6VRX5|ensemblfungi:YDL014W	psi-mi:smn_human(display_long)|uniprotkb:SMN1(gene name)|psi-mi:SMN1(display_short)|uniprotkb:SMN(gene name synonym)|uniprotkb:SMNT(gene name synonym)|uniprotkb:SMN2(gene name)|psi-mi:SMN2(display_short)|uniprotkb:SMNC(gene name synonym)|uniprotkb:Component of gems 1(gene name synonym)|uniprotkb:Gemin-1(gene name synonym)	psi-mi:fbrl_yeast(display_long)|uniprotkb:NOP1(gene name)|psi-mi:NOP1(display_short)|uniprotkb:LOT3(gene name synonym)|uniprotkb:YDL014W(locus name)|uniprotkb:D2870(orf name)|uniprotkb:U3 small nucleolar RNA-associated protein NOP1(gene name synonym)|uniprotkb:Histone-glutamine methyltransferase(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551768|imex:IM-24995-3513	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000335.1|refseq:NP_059107.1|refseq:NP_075012.1|refseq:NP_075013.1|refseq:NP_075014.1|refseq:NP_075015.1|ensembl:ENSG00000172062(gene)|ensembl:ENSG00000205571(gene)|ensembl:ENSG00000273772(gene)|ensembl:ENSG00000275349(gene)|ensembl:ENSG00000277773(gene)|ensembl:ENST00000351205(transcript)|ensembl:ENST00000380707(transcript)|ensembl:ENST00000380741(transcript)|ensembl:ENST00000380743(transcript)|ensembl:ENST00000614610(transcript)|ensembl:ENST00000618251(transcript)|ensembl:ENST00000618661(transcript)|ensembl:ENST00000622739(transcript)|ensembl:ENST00000627341(transcript)|ensembl:ENST00000629122(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0007399"(nervous system development)|go:"GO:0015030"(Cajal body)|go:"GO:0016604"(nuclear body)|go:"GO:0030018"(Z disc)|go:"GO:0030424"(axon)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043204"(perikaryon)|go:"GO:0097504"(Gemini of coiled bodies)|interpro:IPR002999(Tudor)|interpro:IPR010304(Survival motor neuron)|mint:Q16637|rcsb pdb:1G5V|rcsb pdb:1MHN|rcsb pdb:2LEH|rcsb pdb:4A4E|rcsb pdb:4A4G|rcsb pdb:4GLI|rcsb pdb:4QQ6|rcsb pdb:5XJL|go:"GO:0034719"(SMN-Sm protein complex)|rcsb pdb:5XJQ|rcsb pdb:5XJR|rcsb pdb:5XJS|rcsb pdb:5XJT|rcsb pdb:5XJU|reactome:R-HSA-191859|go:"GO:0032797"(SMN complex)|refseq:NP_001284644.1|ensembl:ENSP00000305857|ensembl:ENSP00000370083|ensembl:ENSP00000370117|ensembl:ENST00000380742|ensembl:ENSP00000370118|ensembl:ENSP00000370119|ensembl:ENST00000503079|ensembl:ENSP00000428128|ensembl:ENST00000506163|ensembl:ENSP00000424926|ensembl:ENST00000611442|ensembl:ENSP00000483768|ensembl:ENST00000614240|ensembl:ENSP00000479279|ensembl:ENSP00000479920|ensembl:ENST00000614773|ensembl:ENSP00000481427|ensembl:ENSP00000483515|ensembl:ENSP00000483819|ensembl:ENST00000622158|ensembl:ENSP00000480906|ensembl:ENSP00000482966|ensembl:ENST00000624634|ensembl:ENSP00000485595|ensembl:ENST00000626847|ensembl:ENSP00000486152|ensembl:ENSP00000487421|ensembl:ENST00000628353|ensembl:ENSP00000487029|ensembl:ENST00000628642|ensembl:ENSP00000487015|ensembl:ENSP00000487206|refseq:XP_016865275.1|dip:DIP-31309N	refseq:NP_010270.1|sgd:S000002172|mint:P15646|dip:DIP-698N|ensemblfungi:YDL014W(gene)|ensemblfungi:YDL014W_mRNA(transcript)|go:"GO:0000451"(rRNA 2'-O-methylation)|go:"GO:0000494"(box C/D RNA 3'-end processing)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006356"(regulation of transcription by RNA polymerase I)|go:"GO:0006364"(rRNA processing)|go:"GO:0008171"(O-methyltransferase activity)|go:"GO:0008649"(rRNA methyltransferase activity)|go:"GO:0030686"(90S preribosome)|go:"GO:0031167"(rRNA methylation)|go:"GO:0031428"(box C/D RNP complex)|go:"GO:0032040"(small-subunit processome)|go:"GO:0043144"("sno(s)RNA processing")|go:"GO:1990258"(histone glutamine methylation)|go:"GO:1990259"(histone-glutamine methyltransferase activity)|interpro:IPR000692(Fibrillarin)|interpro:IPR020813|interpro:IPR029063|rcsb pdb:5WLC|rcsb pdb:5WYJ|rcsb pdb:5WYK|rcsb pdb:6KE6|rcsb pdb:6LQP|rcsb pdb:6LQQ|rcsb pdb:6LQR|rcsb pdb:6LQS|rcsb pdb:6LQT|rcsb pdb:6LQU|rcsb pdb:6LQV|rcsb pdb:6ND4|rcsb pdb:6ZDT|rcsb pdb:6ZQA|rcsb pdb:6ZQB|rcsb pdb:6ZQC|rcsb pdb:6ZQD|rcsb pdb:6ZQE|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-6791226	-	-	crc64:56A8B958A7B6066E	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:QGivm7E8suciCWXO4l0zCUzCl2g9606	rogid:zc81RbHf8PxId/8oPXPD3/MpmBU559292	intact-crc:BA7A70E5DC6914A0|rigid:lM0zfvKUz7wkBKJV2PFPNPJ+goI	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P47086	uniprotkb:Q16637	intact:EBI-26299|uniprotkb:D6VWI7|uniprotkb:Q6Q5N5|ensemblfungi:YJR011C	intact:EBI-395421|uniprotkb:Q13119|uniprotkb:Q549U5|uniprotkb:Q96J51|ensembl:ENSP00000305857|uniprotkb:A8K0V4|ensembl:ENSP00000370083|ensembl:ENSP00000370117|ensembl:ENSP00000370119|ensembl:ENSP00000479920|ensembl:ENSP00000482966|ensembl:ENSP00000483515|ensembl:ENSP00000483819|ensembl:ENSP00000487206|ensembl:ENSP00000487421	psi-mi:yjy1_yeast(display_long)|uniprotkb:J1438(orf name)|uniprotkb:YJR83.26(orf name)|uniprotkb:YJR011C(locus name)	psi-mi:smn_human(display_long)|uniprotkb:SMN1(gene name)|psi-mi:SMN1(display_short)|uniprotkb:SMN(gene name synonym)|uniprotkb:SMNT(gene name synonym)|uniprotkb:SMN2(gene name)|psi-mi:SMN2(display_short)|uniprotkb:SMNC(gene name synonym)|uniprotkb:Component of gems 1(gene name synonym)|uniprotkb:Gemin-1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551784|imex:IM-24995-3517	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003772|refseq:NP_012545.1|mint:P47086|dip:DIP-5694N|ensemblfungi:YJR011C(gene)|ensemblfungi:YJR011C_mRNA(transcript)	refseq:NP_000335.1|refseq:NP_059107.1|refseq:NP_075012.1|refseq:NP_075013.1|refseq:NP_075014.1|refseq:NP_075015.1|ensembl:ENSG00000172062(gene)|ensembl:ENSG00000205571(gene)|ensembl:ENSG00000273772(gene)|ensembl:ENSG00000275349(gene)|ensembl:ENSG00000277773(gene)|ensembl:ENST00000351205(transcript)|ensembl:ENST00000380707(transcript)|ensembl:ENST00000380741(transcript)|ensembl:ENST00000380743(transcript)|ensembl:ENST00000614610(transcript)|ensembl:ENST00000618251(transcript)|ensembl:ENST00000618661(transcript)|ensembl:ENST00000622739(transcript)|ensembl:ENST00000627341(transcript)|ensembl:ENST00000629122(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0007399"(nervous system development)|go:"GO:0015030"(Cajal body)|go:"GO:0016604"(nuclear body)|go:"GO:0030018"(Z disc)|go:"GO:0030424"(axon)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043204"(perikaryon)|go:"GO:0097504"(Gemini of coiled bodies)|interpro:IPR002999(Tudor)|interpro:IPR010304(Survival motor neuron)|mint:Q16637|rcsb pdb:1G5V|rcsb pdb:1MHN|rcsb pdb:2LEH|rcsb pdb:4A4E|rcsb pdb:4A4G|rcsb pdb:4GLI|rcsb pdb:4QQ6|rcsb pdb:5XJL|go:"GO:0034719"(SMN-Sm protein complex)|rcsb pdb:5XJQ|rcsb pdb:5XJR|rcsb pdb:5XJS|rcsb pdb:5XJT|rcsb pdb:5XJU|reactome:R-HSA-191859|go:"GO:0032797"(SMN complex)|refseq:NP_001284644.1|ensembl:ENSP00000305857|ensembl:ENSP00000370083|ensembl:ENSP00000370117|ensembl:ENST00000380742|ensembl:ENSP00000370118|ensembl:ENSP00000370119|ensembl:ENST00000503079|ensembl:ENSP00000428128|ensembl:ENST00000506163|ensembl:ENSP00000424926|ensembl:ENST00000611442|ensembl:ENSP00000483768|ensembl:ENST00000614240|ensembl:ENSP00000479279|ensembl:ENSP00000479920|ensembl:ENST00000614773|ensembl:ENSP00000481427|ensembl:ENSP00000483515|ensembl:ENSP00000483819|ensembl:ENST00000622158|ensembl:ENSP00000480906|ensembl:ENSP00000482966|ensembl:ENST00000624634|ensembl:ENSP00000485595|ensembl:ENST00000626847|ensembl:ENSP00000486152|ensembl:ENSP00000487421|ensembl:ENST00000628353|ensembl:ENSP00000487029|ensembl:ENST00000628642|ensembl:ENSP00000487015|ensembl:ENSP00000487206|refseq:XP_016865275.1|dip:DIP-31309N	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:b7YXohJEN6FMN8gYKAKboZQkxvQ559292	rogid:QGivm7E8suciCWXO4l0zCUzCl2g9606	intact-crc:A53A6D10AA750BA4|rigid:ZQ6NMREfPqDMd+YBfYo0Pj7l2A0	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P39990	uniprotkb:Q16637	intact:EBI-12032|ensemblfungi:YEL026W|uniprotkb:D3DLM2	intact:EBI-395421|uniprotkb:Q13119|uniprotkb:Q549U5|uniprotkb:Q96J51|ensembl:ENSP00000305857|uniprotkb:A8K0V4|ensembl:ENSP00000370083|ensembl:ENSP00000370117|ensembl:ENSP00000370119|ensembl:ENSP00000479920|ensembl:ENSP00000482966|ensembl:ENSP00000483515|ensembl:ENSP00000483819|ensembl:ENSP00000487206|ensembl:ENSP00000487421	psi-mi:snu13_yeast(display_long)|uniprotkb:YEL026W(locus name)|uniprotkb:SNU13(gene name)|psi-mi:SNU13(display_short)|uniprotkb:Small nuclear ribonucleoprotein-associated protein 1(gene name synonym)	psi-mi:smn_human(display_long)|uniprotkb:SMN1(gene name)|psi-mi:SMN1(display_short)|uniprotkb:SMN(gene name synonym)|uniprotkb:SMNT(gene name synonym)|uniprotkb:SMN2(gene name)|psi-mi:SMN2(display_short)|uniprotkb:SMNC(gene name synonym)|uniprotkb:Component of gems 1(gene name synonym)|uniprotkb:Gemin-1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551772|imex:IM-24995-3514	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YEL026W(gene)|ensemblfungi:YEL026W_mRNA(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0030490"(maturation of SSU-rRNA)|go:"GO:0030621"(U4 snRNA binding)|go:"GO:0031428"(box C/D RNP complex)|go:"GO:0032040"(small-subunit processome)|go:"GO:0034511"(U3 snoRNA binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:1905216"(positive regulation of RNA binding)|interpro:IPR002415(High mobility group-like nuclear protein)|interpro:IPR004037(Ribosomal protein L7Ae)|interpro:IPR004038(Ribosomal protein L7Ae/L30e/S12e/Gadd45)|interpro:IPR018492|interpro:IPR029064|rcsb pdb:1ZWZ|rcsb pdb:2ALE|rcsb pdb:3JCM|go:"GO:0005654"(nucleoplasm)|rcsb pdb:5GAN|rcsb pdb:5GAP|rcsb pdb:5NRL|rcsb pdb:5TZS|rcsb pdb:5WLC|rcsb pdb:5WYJ|rcsb pdb:5WYK|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:6KE6|rcsb pdb:6LQP|rcsb pdb:6LQQ|rcsb pdb:6LQR|rcsb pdb:6LQS|rcsb pdb:6LQT|rcsb pdb:6LQU|rcsb pdb:6LQV|rcsb pdb:6ND4|rcsb pdb:6ZQA|rcsb pdb:6ZQB|rcsb pdb:6ZQC|rcsb pdb:6ZQD|rcsb pdb:6ZQE|rcsb pdb:7AJT|rcsb pdb:7AJU|rcsb pdb:4NUT|reactome:R-SCE-6791226|refseq:NP_010888.1|sgd:S000000752|mint:P39990|dip:DIP-2870N	refseq:NP_000335.1|refseq:NP_059107.1|refseq:NP_075012.1|refseq:NP_075013.1|refseq:NP_075014.1|refseq:NP_075015.1|ensembl:ENSG00000172062(gene)|ensembl:ENSG00000205571(gene)|ensembl:ENSG00000273772(gene)|ensembl:ENSG00000275349(gene)|ensembl:ENSG00000277773(gene)|ensembl:ENST00000351205(transcript)|ensembl:ENST00000380707(transcript)|ensembl:ENST00000380741(transcript)|ensembl:ENST00000380743(transcript)|ensembl:ENST00000614610(transcript)|ensembl:ENST00000618251(transcript)|ensembl:ENST00000618661(transcript)|ensembl:ENST00000622739(transcript)|ensembl:ENST00000627341(transcript)|ensembl:ENST00000629122(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0007399"(nervous system development)|go:"GO:0015030"(Cajal body)|go:"GO:0016604"(nuclear body)|go:"GO:0030018"(Z disc)|go:"GO:0030424"(axon)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043204"(perikaryon)|go:"GO:0097504"(Gemini of coiled bodies)|interpro:IPR002999(Tudor)|interpro:IPR010304(Survival motor neuron)|mint:Q16637|rcsb pdb:1G5V|rcsb pdb:1MHN|rcsb pdb:2LEH|rcsb pdb:4A4E|rcsb pdb:4A4G|rcsb pdb:4GLI|rcsb pdb:4QQ6|rcsb pdb:5XJL|go:"GO:0034719"(SMN-Sm protein complex)|rcsb pdb:5XJQ|rcsb pdb:5XJR|rcsb pdb:5XJS|rcsb pdb:5XJT|rcsb pdb:5XJU|reactome:R-HSA-191859|go:"GO:0032797"(SMN complex)|refseq:NP_001284644.1|ensembl:ENSP00000305857|ensembl:ENSP00000370083|ensembl:ENSP00000370117|ensembl:ENST00000380742|ensembl:ENSP00000370118|ensembl:ENSP00000370119|ensembl:ENST00000503079|ensembl:ENSP00000428128|ensembl:ENST00000506163|ensembl:ENSP00000424926|ensembl:ENST00000611442|ensembl:ENSP00000483768|ensembl:ENST00000614240|ensembl:ENSP00000479279|ensembl:ENSP00000479920|ensembl:ENST00000614773|ensembl:ENSP00000481427|ensembl:ENSP00000483515|ensembl:ENSP00000483819|ensembl:ENST00000622158|ensembl:ENSP00000480906|ensembl:ENSP00000482966|ensembl:ENST00000624634|ensembl:ENSP00000485595|ensembl:ENST00000626847|ensembl:ENSP00000486152|ensembl:ENSP00000487421|ensembl:ENST00000628353|ensembl:ENSP00000487029|ensembl:ENST00000628642|ensembl:ENSP00000487015|ensembl:ENSP00000487206|refseq:XP_016865275.1|dip:DIP-31309N	-	crc64:4489780153E8F182	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:4C07wkvZ4Nts4Oxw4/L7QMkwcmE559292	rogid:QGivm7E8suciCWXO4l0zCUzCl2g9606	intact-crc:9DA0FE33EA7FFBA4|rigid:1WMvd1mwKFzwChd4wkZR1F0aP18	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q16637	intact:EBI-11522403	intact:EBI-395421|uniprotkb:Q13119|uniprotkb:Q549U5|uniprotkb:Q96J51|ensembl:ENSP00000305857|uniprotkb:A8K0V4|ensembl:ENSP00000370083|ensembl:ENSP00000370117|ensembl:ENSP00000370119|ensembl:ENSP00000479920|ensembl:ENSP00000482966|ensembl:ENSP00000483515|ensembl:ENSP00000483819|ensembl:ENSP00000487206|ensembl:ENSP00000487421	-	psi-mi:smn_human(display_long)|uniprotkb:SMN1(gene name)|psi-mi:SMN1(display_short)|uniprotkb:SMN(gene name synonym)|uniprotkb:SMNT(gene name synonym)|uniprotkb:SMN2(gene name)|psi-mi:SMN2(display_short)|uniprotkb:SMNC(gene name synonym)|uniprotkb:Component of gems 1(gene name synonym)|uniprotkb:Gemin-1(gene name synonym)	psi-mi:nhp2(display_short)|psi-mi:EBI-11522403(display_long)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551776|imex:IM-24995-3515	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000335.1|refseq:NP_059107.1|refseq:NP_075012.1|refseq:NP_075013.1|refseq:NP_075014.1|refseq:NP_075015.1|ensembl:ENSG00000172062(gene)|ensembl:ENSG00000205571(gene)|ensembl:ENSG00000273772(gene)|ensembl:ENSG00000275349(gene)|ensembl:ENSG00000277773(gene)|ensembl:ENST00000351205(transcript)|ensembl:ENST00000380707(transcript)|ensembl:ENST00000380741(transcript)|ensembl:ENST00000380743(transcript)|ensembl:ENST00000614610(transcript)|ensembl:ENST00000618251(transcript)|ensembl:ENST00000618661(transcript)|ensembl:ENST00000622739(transcript)|ensembl:ENST00000627341(transcript)|ensembl:ENST00000629122(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0007399"(nervous system development)|go:"GO:0015030"(Cajal body)|go:"GO:0016604"(nuclear body)|go:"GO:0030018"(Z disc)|go:"GO:0030424"(axon)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043204"(perikaryon)|go:"GO:0097504"(Gemini of coiled bodies)|interpro:IPR002999(Tudor)|interpro:IPR010304(Survival motor neuron)|mint:Q16637|rcsb pdb:1G5V|rcsb pdb:1MHN|rcsb pdb:2LEH|rcsb pdb:4A4E|rcsb pdb:4A4G|rcsb pdb:4GLI|rcsb pdb:4QQ6|rcsb pdb:5XJL|go:"GO:0034719"(SMN-Sm protein complex)|rcsb pdb:5XJQ|rcsb pdb:5XJR|rcsb pdb:5XJS|rcsb pdb:5XJT|rcsb pdb:5XJU|reactome:R-HSA-191859|go:"GO:0032797"(SMN complex)|refseq:NP_001284644.1|ensembl:ENSP00000305857|ensembl:ENSP00000370083|ensembl:ENSP00000370117|ensembl:ENST00000380742|ensembl:ENSP00000370118|ensembl:ENSP00000370119|ensembl:ENST00000503079|ensembl:ENSP00000428128|ensembl:ENST00000506163|ensembl:ENSP00000424926|ensembl:ENST00000611442|ensembl:ENSP00000483768|ensembl:ENST00000614240|ensembl:ENSP00000479279|ensembl:ENSP00000479920|ensembl:ENST00000614773|ensembl:ENSP00000481427|ensembl:ENSP00000483515|ensembl:ENSP00000483819|ensembl:ENST00000622158|ensembl:ENSP00000480906|ensembl:ENSP00000482966|ensembl:ENST00000624634|ensembl:ENSP00000485595|ensembl:ENST00000626847|ensembl:ENSP00000486152|ensembl:ENSP00000487421|ensembl:ENST00000628353|ensembl:ENSP00000487029|ensembl:ENST00000628642|ensembl:ENSP00000487015|ensembl:ENSP00000487206|refseq:XP_016865275.1|dip:DIP-31309N	-	-	-	no-uniprot-update:	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:QGivm7E8suciCWXO4l0zCUzCl2g9606	rogid:FFduCSFjK3s7VNWPyW67FjyPE7Y4932	intact-crc:5871A468B0ED17D9|rigid:kJnLGc37hChO//AWrVZFL3x7IuY	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P38340	uniprotkb:Q16637	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-395421|uniprotkb:Q13119|uniprotkb:Q549U5|uniprotkb:Q96J51|ensembl:ENSP00000305857|uniprotkb:A8K0V4|ensembl:ENSP00000370083|ensembl:ENSP00000370117|ensembl:ENSP00000370119|ensembl:ENSP00000479920|ensembl:ENSP00000482966|ensembl:ENSP00000483515|ensembl:ENSP00000483819|ensembl:ENSP00000487206|ensembl:ENSP00000487421	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:smn_human(display_long)|uniprotkb:SMN1(gene name)|psi-mi:SMN1(display_short)|uniprotkb:SMN(gene name synonym)|uniprotkb:SMNT(gene name synonym)|uniprotkb:SMN2(gene name)|psi-mi:SMN2(display_short)|uniprotkb:SMNC(gene name synonym)|uniprotkb:Component of gems 1(gene name synonym)|uniprotkb:Gemin-1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551780|imex:IM-24995-3516	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F	refseq:NP_000335.1|refseq:NP_059107.1|refseq:NP_075012.1|refseq:NP_075013.1|refseq:NP_075014.1|refseq:NP_075015.1|ensembl:ENSG00000172062(gene)|ensembl:ENSG00000205571(gene)|ensembl:ENSG00000273772(gene)|ensembl:ENSG00000275349(gene)|ensembl:ENSG00000277773(gene)|ensembl:ENST00000351205(transcript)|ensembl:ENST00000380707(transcript)|ensembl:ENST00000380741(transcript)|ensembl:ENST00000380743(transcript)|ensembl:ENST00000614610(transcript)|ensembl:ENST00000618251(transcript)|ensembl:ENST00000618661(transcript)|ensembl:ENST00000622739(transcript)|ensembl:ENST00000627341(transcript)|ensembl:ENST00000629122(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0007399"(nervous system development)|go:"GO:0015030"(Cajal body)|go:"GO:0016604"(nuclear body)|go:"GO:0030018"(Z disc)|go:"GO:0030424"(axon)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043204"(perikaryon)|go:"GO:0097504"(Gemini of coiled bodies)|interpro:IPR002999(Tudor)|interpro:IPR010304(Survival motor neuron)|mint:Q16637|rcsb pdb:1G5V|rcsb pdb:1MHN|rcsb pdb:2LEH|rcsb pdb:4A4E|rcsb pdb:4A4G|rcsb pdb:4GLI|rcsb pdb:4QQ6|rcsb pdb:5XJL|go:"GO:0034719"(SMN-Sm protein complex)|rcsb pdb:5XJQ|rcsb pdb:5XJR|rcsb pdb:5XJS|rcsb pdb:5XJT|rcsb pdb:5XJU|reactome:R-HSA-191859|go:"GO:0032797"(SMN complex)|refseq:NP_001284644.1|ensembl:ENSP00000305857|ensembl:ENSP00000370083|ensembl:ENSP00000370117|ensembl:ENST00000380742|ensembl:ENSP00000370118|ensembl:ENSP00000370119|ensembl:ENST00000503079|ensembl:ENSP00000428128|ensembl:ENST00000506163|ensembl:ENSP00000424926|ensembl:ENST00000611442|ensembl:ENSP00000483768|ensembl:ENST00000614240|ensembl:ENSP00000479279|ensembl:ENSP00000479920|ensembl:ENST00000614773|ensembl:ENSP00000481427|ensembl:ENSP00000483515|ensembl:ENSP00000483819|ensembl:ENST00000622158|ensembl:ENSP00000480906|ensembl:ENSP00000482966|ensembl:ENST00000624634|ensembl:ENSP00000485595|ensembl:ENST00000626847|ensembl:ENSP00000486152|ensembl:ENSP00000487421|ensembl:ENST00000628353|ensembl:ENSP00000487029|ensembl:ENST00000628642|ensembl:ENSP00000487015|ensembl:ENSP00000487206|refseq:XP_016865275.1|dip:DIP-31309N	-	crc64:66699F37B0013088	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:QGivm7E8suciCWXO4l0zCUzCl2g9606	intact-crc:FDD7C615397F1899|rigid:Kq/4LIJwTNVmItvsCg9v0/vIhBM	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q12460	uniprotkb:Q16637-3	intact:EBI-17148|ensemblfungi:YLR197W|uniprotkb:D6VYK0	intact:EBI-395447|ensembl:ENSP00000424926|ensembl:ENSP00000486152|ensembl:ENSP00000487015|ensembl:ENSP00000487029|intact:EBI-8628183|intact:MINT-95595	psi-mi:nop56_yeast(display_long)|uniprotkb:SIK1(gene name synonym)|uniprotkb:Ribosome biosynthesis protein SIK1(gene name synonym)|uniprotkb:YLR197W(locus name)|uniprotkb:L8167.9(orf name)|uniprotkb:NOP56(gene name)|psi-mi:NOP56(display_short)|uniprotkb:Suppressor of I kappa b protein 1(gene name synonym)	psi-mi:q16637-3(display_long)|uniprotkb:Iso7-SMN(isoform synonym)|uniprotkb:SMN1(gene name)|psi-mi:SMN1(display_short)|uniprotkb:SMN2(gene name)|psi-mi:SMN2(display_short)|uniprotkb:SMN(gene name synonym)|uniprotkb:SMNT(gene name synonym)|uniprotkb:SMNC(gene name synonym)|uniprotkb:Component of gems 1(gene name synonym)|uniprotkb:Gemin-1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551788|imex:IM-24995-3518	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YLR197W(gene)|ensemblfungi:YLR197W_mRNA(transcript)|go:"GO:0000154"(rRNA modification)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|refseq:NP_013298.1|sgd:S000004187|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0030515"(snoRNA binding)|go:"GO:0030686"(90S preribosome)|go:"GO:0031428"(box C/D RNP complex)|go:"GO:0032040"(small-subunit processome)|interpro:IPR002687(Pre-mRNA processing ribonucleoprotein, binding region)|interpro:IPR012974(NOP5, N-terminal)|interpro:IPR012976(NOSIC)|interpro:IPR036070|interpro:IPR042239|rcsb pdb:5WLC|rcsb pdb:5WYJ|rcsb pdb:5WYK|rcsb pdb:6KE6|rcsb pdb:6LQP|rcsb pdb:6LQQ|rcsb pdb:6LQR|rcsb pdb:6LQS|rcsb pdb:6LQT|rcsb pdb:6LQU|rcsb pdb:6LQV|rcsb pdb:6ND4|rcsb pdb:6ZDT|rcsb pdb:6ZQA|rcsb pdb:6ZQB|rcsb pdb:6ZQC|rcsb pdb:6ZQD|rcsb pdb:6ZQE|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-6791226|dip:DIP-4405N|mint:Q12460	intact:EBI-395421(smn_human)|ensembl:ENSG00000275349(gene)|ensembl:ENST00000506163(transcript)|ensembl:ENST00000626847(transcript)|ensembl:ENST00000628353(transcript)|ensembl:ENST00000628642(transcript)|ensembl:ENSG00000172062(gene)|ensembl:ENSG00000205571(gene)|ensembl:ENSG00000273772(gene)|uniprotkb:Q16637-3(isoform-parent)	-	crc64:F8522A5870EF4842	isoform-comment:Thought to be a non-functional protein that lacks the capacity to oligomerize and thus cannot interact with Sm proteins. Primarily derived from SMN2 gene.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:l3UAmoOUECH1uov6nv7MSwSv/3s559292	rogid:ICA63eidVxJ219M+YZJ20zNh+xU9606	intact-crc:C0A188A9E8497F50|rigid:SFi50B0QqmFhNR2JwpnQnRCGfjs	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q3E793	uniprotkb:P98170	intact:EBI-2344281|uniprotkb:D6VPH1|ensemblfungi:YAL044W-A	intact:EBI-517127|uniprotkb:Q9NQ14|uniprotkb:D3DTF2|ensembl:ENSP00000347858|ensembl:ENSP00000360242|ensembl:ENSP00000395230	psi-mi:bol1_yeast(display_long)|uniprotkb:BOL1(gene name)|psi-mi:BOL1(display_short)|uniprotkb:YAL044W-A(locus name)	psi-mi:xiap_human(display_long)|uniprotkb:Inhibitor of apoptosis protein 3(gene name synonym)|uniprotkb:X-linked inhibitor of apoptosis protein(gene name synonym)|uniprotkb:IAP-like protein(gene name synonym)|uniprotkb:XIAP(gene name)|psi-mi:XIAP(display_short)|uniprotkb:API3(gene name synonym)|uniprotkb:IAP3(gene name synonym)|uniprotkb:BIRC4(gene name synonym)|uniprotkb:Baculoviral IAP repeat-containing protein 4(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase XIAP(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551824|imex:IM-24995-3527	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_075206.1|sgd:S000007586|interpro:IPR002634(BolA-like protein)|interpro:IPR036065|ensemblfungi:YAL044W-A(gene)|ensemblfungi:YAL044W-A_mRNA(transcript)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0044572"([4Fe-4S] cluster assembly)|go:"GO:0106035"(protein maturation by [4Fe-4S] cluster transfer)	refseq:XP_006724817.1|refseq:NP_001158.2|refseq:NP_001191330.1|refseq:XP_011529631.1|dip:DIP-27626N|ensembl:ENSG00000101966(gene)|ensembl:ENST00000355640(transcript)|ensembl:ENST00000371199(transcript)|ensembl:ENST00000434753(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005876"(spindle microtubule)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030510"(regulation of BMP signaling pathway)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0055070"(copper ion homeostasis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070424"(regulation of nucleotide-binding oligomerization domain containing signaling pathway)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:1902530"(positive regulation of protein linear polyubiquitination)|go:"GO:1990001"(inhibition of cysteine-type endopeptidase activity involved in apoptotic process)|interpro:IPR001370(Proteinase inhibitor I32, inhibitor of apoptosis)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011029(DEATH-like)|interpro:IPR042579|mint:P98170|rcsb pdb:1C9Q|rcsb pdb:1F9X|rcsb pdb:1G3F|rcsb pdb:1G73|rcsb pdb:1I3O|rcsb pdb:1I4O|rcsb pdb:1I51|rcsb pdb:1KMC|rcsb pdb:1NW9|rcsb pdb:1TFQ|rcsb pdb:1TFT|rcsb pdb:2ECG|rcsb pdb:2JK7|rcsb pdb:2KNA|rcsb pdb:2OPY|rcsb pdb:2OPZ|rcsb pdb:2POI|rcsb pdb:2POP|rcsb pdb:2QRA|rcsb pdb:2VSL|rcsb pdb:3CLX|rcsb pdb:3CM2|rcsb pdb:3CM7|rcsb pdb:3EYL|rcsb pdb:3G76|rcsb pdb:3HL5|rcsb pdb:3UW4|rcsb pdb:3UW5|rcsb pdb:4EC4|rcsb pdb:4HY0|rcsb pdb:4IC2|rcsb pdb:4IC3|rcsb pdb:4J3Y|rcsb pdb:4J44|rcsb pdb:4J45|rcsb pdb:4J46|rcsb pdb:4J47|rcsb pdb:4J48|rcsb pdb:4KJU|rcsb pdb:4KJV|rcsb pdb:4KMP|rcsb pdb:4MTZ|rcsb pdb:4OXC|rcsb pdb:4WVS|rcsb pdb:4WVT|rcsb pdb:4WVU|rcsb pdb:5C0K|rcsb pdb:5C0L|rcsb pdb:5C3H|rcsb pdb:5C3K|rcsb pdb:5C7A|rcsb pdb:5C7B|rcsb pdb:5C7C|rcsb pdb:5C7D|rcsb pdb:5C83|rcsb pdb:5C84|rcsb pdb:5M6E|rcsb pdb:5M6F|rcsb pdb:5M6H|rcsb pdb:5M6L|rcsb pdb:5M6M|rcsb pdb:5O6T|rcsb pdb:5OQW|rcsb pdb:6EY2|rcsb pdb:6GJW|rcsb pdb:6QCI|reactome:R-HSA-111459|reactome:R-HSA-111463|reactome:R-HSA-111464|reactome:R-HSA-111469|reactome:R-HSA-3769402|reactome:R-HSA-5213460|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5675482|reactome:R-HSA-8948747|reactome:R-HSA-8948751|reactome:R-HSA-9627069	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:9pYGPvGIU56X3neAXP8LQXxWfC4559292	rogid:6eDcOay+c2ZmIAD/pwnCDROBwgM9606	intact-crc:D7BB617FCC67B770|rigid:53Mz0OG+9oFHUkS4vej15mgo2lo	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P39990	uniprotkb:Q16637-3	intact:EBI-12032|ensemblfungi:YEL026W|uniprotkb:D3DLM2	intact:EBI-395447|ensembl:ENSP00000424926|ensembl:ENSP00000486152|ensembl:ENSP00000487015|ensembl:ENSP00000487029|intact:EBI-8628183|intact:MINT-95595	psi-mi:snu13_yeast(display_long)|uniprotkb:YEL026W(locus name)|uniprotkb:SNU13(gene name)|psi-mi:SNU13(display_short)|uniprotkb:Small nuclear ribonucleoprotein-associated protein 1(gene name synonym)	psi-mi:q16637-3(display_long)|uniprotkb:Iso7-SMN(isoform synonym)|uniprotkb:SMN1(gene name)|psi-mi:SMN1(display_short)|uniprotkb:SMN2(gene name)|psi-mi:SMN2(display_short)|uniprotkb:SMN(gene name synonym)|uniprotkb:SMNT(gene name synonym)|uniprotkb:SMNC(gene name synonym)|uniprotkb:Component of gems 1(gene name synonym)|uniprotkb:Gemin-1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551800|imex:IM-24995-3521	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YEL026W(gene)|ensemblfungi:YEL026W_mRNA(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0030490"(maturation of SSU-rRNA)|go:"GO:0030621"(U4 snRNA binding)|go:"GO:0031428"(box C/D RNP complex)|go:"GO:0032040"(small-subunit processome)|go:"GO:0034511"(U3 snoRNA binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:1905216"(positive regulation of RNA binding)|interpro:IPR002415(High mobility group-like nuclear protein)|interpro:IPR004037(Ribosomal protein L7Ae)|interpro:IPR004038(Ribosomal protein L7Ae/L30e/S12e/Gadd45)|interpro:IPR018492|interpro:IPR029064|rcsb pdb:1ZWZ|rcsb pdb:2ALE|rcsb pdb:3JCM|go:"GO:0005654"(nucleoplasm)|rcsb pdb:5GAN|rcsb pdb:5GAP|rcsb pdb:5NRL|rcsb pdb:5TZS|rcsb pdb:5WLC|rcsb pdb:5WYJ|rcsb pdb:5WYK|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:6KE6|rcsb pdb:6LQP|rcsb pdb:6LQQ|rcsb pdb:6LQR|rcsb pdb:6LQS|rcsb pdb:6LQT|rcsb pdb:6LQU|rcsb pdb:6LQV|rcsb pdb:6ND4|rcsb pdb:6ZQA|rcsb pdb:6ZQB|rcsb pdb:6ZQC|rcsb pdb:6ZQD|rcsb pdb:6ZQE|rcsb pdb:7AJT|rcsb pdb:7AJU|rcsb pdb:4NUT|reactome:R-SCE-6791226|refseq:NP_010888.1|sgd:S000000752|mint:P39990|dip:DIP-2870N	intact:EBI-395421(smn_human)|ensembl:ENSG00000275349(gene)|ensembl:ENST00000506163(transcript)|ensembl:ENST00000626847(transcript)|ensembl:ENST00000628353(transcript)|ensembl:ENST00000628642(transcript)|ensembl:ENSG00000172062(gene)|ensembl:ENSG00000205571(gene)|ensembl:ENSG00000273772(gene)|uniprotkb:Q16637-3(isoform-parent)	-	crc64:4489780153E8F182	isoform-comment:Thought to be a non-functional protein that lacks the capacity to oligomerize and thus cannot interact with Sm proteins. Primarily derived from SMN2 gene.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:4C07wkvZ4Nts4Oxw4/L7QMkwcmE559292	rogid:ICA63eidVxJ219M+YZJ20zNh+xU9606	intact-crc:70ECD402040DB0B5|rigid:gHrDiO7IspHzzgYrGnScU0x9cyM	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q16637-3	intact:EBI-11522403	intact:EBI-395447|ensembl:ENSP00000424926|ensembl:ENSP00000486152|ensembl:ENSP00000487015|ensembl:ENSP00000487029|intact:EBI-8628183|intact:MINT-95595	-	psi-mi:q16637-3(display_long)|uniprotkb:Iso7-SMN(isoform synonym)|uniprotkb:SMN1(gene name)|psi-mi:SMN1(display_short)|uniprotkb:SMN2(gene name)|psi-mi:SMN2(display_short)|uniprotkb:SMN(gene name synonym)|uniprotkb:SMNT(gene name synonym)|uniprotkb:SMNC(gene name synonym)|uniprotkb:Component of gems 1(gene name synonym)|uniprotkb:Gemin-1(gene name synonym)	psi-mi:nhp2(display_short)|psi-mi:EBI-11522403(display_long)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551804|imex:IM-24995-3522	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-395421(smn_human)|ensembl:ENSG00000275349(gene)|ensembl:ENST00000506163(transcript)|ensembl:ENST00000626847(transcript)|ensembl:ENST00000628353(transcript)|ensembl:ENST00000628642(transcript)|ensembl:ENSG00000172062(gene)|ensembl:ENSG00000205571(gene)|ensembl:ENSG00000273772(gene)|uniprotkb:Q16637-3(isoform-parent)	-	-	isoform-comment:Thought to be a non-functional protein that lacks the capacity to oligomerize and thus cannot interact with Sm proteins. Primarily derived from SMN2 gene.	no-uniprot-update:	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:ICA63eidVxJ219M+YZJ20zNh+xU9606	rogid:FFduCSFjK3s7VNWPyW67FjyPE7Y4932	intact-crc:2F247B03092B751B|rigid:F+LPh6d3R3r87DAdu/iZ1G3pXbA	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P25635	uniprotkb:Q2NKX8	intact:EBI-14332|uniprotkb:P25633|uniprotkb:P25636|uniprotkb:D6VR63|ensemblfungi:YCR057C	intact:EBI-1042535|uniprotkb:Q8NCI1|uniprotkb:Q96H93|uniprotkb:Q9NXQ8|intact:EBI-2560904|ensembl:ENSP00000334675	psi-mi:pwp2_yeast(display_long)|uniprotkb:PWP2(gene name)|psi-mi:PWP2(display_short)|uniprotkb:UTP1(gene name synonym)|uniprotkb:YCR057C(locus name)|uniprotkb:YCR55C/YCR57C/YCR58C(orf name)|uniprotkb:U3 small nucleolar RNA-associated protein 1(gene name synonym)|uniprotkb:U three protein 1(gene name synonym)	psi-mi:erc6l_human(display_long)|uniprotkb:ERCC6L(gene name)|psi-mi:ERCC6L(display_short)|uniprotkb:PICH(gene name synonym)|uniprotkb:ATP-dependent helicase ERCC6-like(gene name synonym)|uniprotkb:PLK1-interacting checkpoint helicase(gene name synonym)|uniprotkb:Tumor antigen BJ-HCC-15(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551808|imex:IM-24995-3523	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0000920"(septum digestion after cytokinesis)|go:"GO:0003729"(mRNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030686"(90S preribosome)|go:"GO:0032040"(small-subunit processome)|go:"GO:0034388"(Pwp2p-containing subcomplex of 90S preribosome)|interpro:IPR001680(WD40 repeat)|interpro:IPR007148(Small-subunit processome, Utp12)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR027145|interpro:IPR036322|rcsb pdb:5I2T|rcsb pdb:5WLC|rcsb pdb:5WYJ|ensemblfungi:YCR057C(gene)|ensemblfungi:YCR057C_mRNA(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0000447"("endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|rcsb pdb:5WYK|go:"GO:0000472"("endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000480"("endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|rcsb pdb:6KE6|rcsb pdb:6LQP|rcsb pdb:6LQQ|rcsb pdb:6LQR|rcsb pdb:6LQS|rcsb pdb:6LQT|rcsb pdb:6LQU|rcsb pdb:6LQV|rcsb pdb:6ND4|rcsb pdb:6ZQA|rcsb pdb:6ZQB|rcsb pdb:6ZQC|rcsb pdb:6ZQD|rcsb pdb:6ZQE|rcsb pdb:6ZQF|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-6791226|refseq:NP_009984.1|sgd:S000000653|mint:P25635|dip:DIP-1868N	refseq:NP_060139.2|ensembl:ENSG00000186871(gene)|ensembl:ENST00000334463(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0015616"(DNA translocase activity)|go:"GO:0016020"(membrane)|go:"GO:0051301"(cell division)|go:"GO:0070615"|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000330(SNF2-related)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR038718|rcsb pdb:5JNO|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025	-	crc64:CBEE4720F81378B6	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:3JKhaE50yPlCymnkEC14JB9atNY559292	rogid:3HZtZq9pgDyQB+UcxtAQjHv7+7o9606	intact-crc:E061568D2F0B0B99|rigid:Lg3oW65HHrRjOLx+yUC5fbxZUKk	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P38340	uniprotkb:Q16637-3	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-395447|ensembl:ENSP00000424926|ensembl:ENSP00000486152|ensembl:ENSP00000487015|ensembl:ENSP00000487029|intact:EBI-8628183|intact:MINT-95595	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:q16637-3(display_long)|uniprotkb:Iso7-SMN(isoform synonym)|uniprotkb:SMN1(gene name)|psi-mi:SMN1(display_short)|uniprotkb:SMN2(gene name)|psi-mi:SMN2(display_short)|uniprotkb:SMN(gene name synonym)|uniprotkb:SMNT(gene name synonym)|uniprotkb:SMNC(gene name synonym)|uniprotkb:Component of gems 1(gene name synonym)|uniprotkb:Gemin-1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551792|imex:IM-24995-3519	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F	intact:EBI-395421(smn_human)|ensembl:ENSG00000275349(gene)|ensembl:ENST00000506163(transcript)|ensembl:ENST00000626847(transcript)|ensembl:ENST00000628353(transcript)|ensembl:ENST00000628642(transcript)|ensembl:ENSG00000172062(gene)|ensembl:ENSG00000205571(gene)|ensembl:ENSG00000273772(gene)|uniprotkb:Q16637-3(isoform-parent)	-	crc64:66699F37B0013088	isoform-comment:Thought to be a non-functional protein that lacks the capacity to oligomerize and thus cannot interact with Sm proteins. Primarily derived from SMN2 gene.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:ICA63eidVxJ219M+YZJ20zNh+xU9606	intact-crc:03BB2F401E47F96B|rigid:wu48ZQpwfDqQm7Y7vGLoNyQek4Q	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q3E793	uniprotkb:O76003	intact:EBI-2344281|uniprotkb:D6VPH1|ensemblfungi:YAL044W-A	intact:EBI-374781|uniprotkb:Q96CE0|uniprotkb:Q9P1B0|uniprotkb:Q9P1B1|uniprotkb:B3KMP7|uniprotkb:B3KMQ5|uniprotkb:Q5JV01|ensembl:ENSP00000330836|ensembl:ENSP00000357633|ensembl:ENSP00000435445|uniprotkb:D3DRG2	psi-mi:bol1_yeast(display_long)|uniprotkb:BOL1(gene name)|psi-mi:BOL1(display_short)|uniprotkb:YAL044W-A(locus name)	psi-mi:glrx3_human(display_long)|uniprotkb:GLRX3(gene name)|psi-mi:GLRX3(display_short)|uniprotkb:Thioredoxin-like protein 2(gene name synonym)|uniprotkb:PKC-interacting cousin of thioredoxin(gene name synonym)|uniprotkb:PKC-theta-interacting protein(gene name synonym)|uniprotkb:PICOT(gene name synonym)|uniprotkb:HUSSY-22(orf name)|uniprotkb:TXNL2(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551816|imex:IM-24995-3525	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_075206.1|sgd:S000007586|interpro:IPR002634(BolA-like protein)|interpro:IPR036065|ensemblfungi:YAL044W-A(gene)|ensemblfungi:YAL044W-A_mRNA(transcript)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0044572"([4Fe-4S] cluster assembly)|go:"GO:0106035"(protein maturation by [4Fe-4S] cluster transfer)	ensembl:ENSG00000108010(gene)|ensembl:ENST00000331244(transcript)|ensembl:ENST00000368644(transcript)|ensembl:ENST00000481034(transcript)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0003723"(RNA binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0030018"(Z disc)|go:"GO:0030425"(dendrite)|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051536"(iron-sulfur cluster binding)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|go:"GO:0097573"(glutathione oxidoreductase activity)|interpro:IPR002109(Glutaredoxin)|interpro:IPR004480(Glutaredoxin-related protein)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR033658|interpro:IPR036249|mint:O76003|rcsb pdb:2DIY|rcsb pdb:2WZ9|rcsb pdb:2YAN|rcsb pdb:3ZYW|reactome:R-HSA-917937|refseq:NP_001186797.1|refseq:NP_006532.2|dip:DIP-31306N	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:9pYGPvGIU56X3neAXP8LQXxWfC4559292	rogid:iKUSt6zbNzzXSKvW+vXMq3hKsEM9606	intact-crc:13D39E8ECF1AA0F6|rigid:97YEt2Aehe3ybPhcvT6guyxTdD4	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q16637-3	uniprotkb:P47086	intact:EBI-395447|ensembl:ENSP00000424926|ensembl:ENSP00000486152|ensembl:ENSP00000487015|ensembl:ENSP00000487029|intact:EBI-8628183|intact:MINT-95595	intact:EBI-26299|uniprotkb:D6VWI7|uniprotkb:Q6Q5N5|ensemblfungi:YJR011C	psi-mi:q16637-3(display_long)|uniprotkb:Iso7-SMN(isoform synonym)|uniprotkb:SMN1(gene name)|psi-mi:SMN1(display_short)|uniprotkb:SMN2(gene name)|psi-mi:SMN2(display_short)|uniprotkb:SMN(gene name synonym)|uniprotkb:SMNT(gene name synonym)|uniprotkb:SMNC(gene name synonym)|uniprotkb:Component of gems 1(gene name synonym)|uniprotkb:Gemin-1(gene name synonym)	psi-mi:yjy1_yeast(display_long)|uniprotkb:J1438(orf name)|uniprotkb:YJR83.26(orf name)|uniprotkb:YJR011C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551796|imex:IM-24995-3520	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-395421(smn_human)|ensembl:ENSG00000275349(gene)|ensembl:ENST00000506163(transcript)|ensembl:ENST00000626847(transcript)|ensembl:ENST00000628353(transcript)|ensembl:ENST00000628642(transcript)|ensembl:ENSG00000172062(gene)|ensembl:ENSG00000205571(gene)|ensembl:ENSG00000273772(gene)|uniprotkb:Q16637-3(isoform-parent)	sgd:S000003772|refseq:NP_012545.1|mint:P47086|dip:DIP-5694N|ensemblfungi:YJR011C(gene)|ensemblfungi:YJR011C_mRNA(transcript)	-	isoform-comment:Thought to be a non-functional protein that lacks the capacity to oligomerize and thus cannot interact with Sm proteins. Primarily derived from SMN2 gene.	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:ICA63eidVxJ219M+YZJ20zNh+xU9606	rogid:b7YXohJEN6FMN8gYKAKboZQkxvQ559292	intact-crc:47A09FD37C490527|rigid:i7drGLsuBejxbIWgVhYb8wIJ0Ls	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q2TAC2-2	uniprotkb:P53255	intact:EBI-10961624|ensembl:ENSP00000376154	intact:EBI-23234|uniprotkb:D6VUM5|ensemblfungi:YGR093W	psi-mi:q2tac2-2(display_long)|uniprotkb:CCDC57(gene name)|psi-mi:CCDC57(display_short)	psi-mi:drn1_yeast(display_long)|uniprotkb:YGR093W(locus name)|uniprotkb:DRN1(gene name)|psi-mi:DRN1(display_short)|uniprotkb:Debranching enzyme-associated ribonuclease 1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551812|imex:IM-24995-3524	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000176155(gene)|ensembl:ENST00000392343(transcript)|uniprotkb:Q2TAC2-2(isoform-parent)|intact:EBI-2808286(isoform-parent)	sgd:S000003325|interpro:IPR006768(Protein similar to CwfJ, C-terminal 1)|interpro:IPR006767(Protein similar to CwfJ, C-terminal 2)|refseq:NP_011607.3|mint:P53255|interpro:IPR040194|interpro:IPR036265|ensemblfungi:YGR093W(gene)|ensemblfungi:YGR093W_mRNA(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0061632"(RNA lariat debranching enzyme activator activity)|go:"GO:0071014"(post-mRNA release spliceosomal complex)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:RWcF0hgb1geIY959JUKrLK13Jx09606	rogid:oQ6T+SDSiEw5VpFLQvV/N6pRszs559292	intact-crc:234B510B0BD451CB|rigid:yQ2+o04bLwn6oSc0s6yweZVglRA	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q13490	uniprotkb:Q3E793	intact:EBI-514538|uniprotkb:Q16516|uniprotkb:Q4TTG0|uniprotkb:B4E026|ensembl:ENSP00000227758|ensembl:ENSP00000477613	intact:EBI-2344281|uniprotkb:D6VPH1|ensemblfungi:YAL044W-A	psi-mi:birc2_human(display_long)|uniprotkb:Inhibitor of apoptosis protein 2(gene name synonym)|uniprotkb:TNFR2-TRAF-signaling complex protein 2(gene name synonym)|uniprotkb:IAP homolog B(gene name synonym)|uniprotkb:RING finger protein 48(gene name synonym)|uniprotkb:BIRC2(gene name)|psi-mi:BIRC2(display_short)|uniprotkb:API1(gene name synonym)|uniprotkb:MIHB(gene name synonym)|uniprotkb:RNF48(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase BIRC2(gene name synonym)|uniprotkb:Cellular inhibitor of apoptosis 1(gene name synonym)	psi-mi:bol1_yeast(display_long)|uniprotkb:BOL1(gene name)|psi-mi:BOL1(display_short)|uniprotkb:YAL044W-A(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551820|imex:IM-24995-3526	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001157.1|refseq:NP_001243095.1|refseq:NP_001243092.1|dip:DIP-33485N|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0045471"(response to ethanol)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051087"(chaperone binding)|go:"GO:0051591"(response to cAMP)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060544"(regulation of necroptotic process)|go:"GO:0060546"(negative regulation of necroptotic process)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070266"(necroptotic process)|go:"GO:0070424"(regulation of nucleotide-binding oligomerization domain containing signaling pathway)|go:"GO:0098770"(FBXO family protein binding)|go:"GO:1901222"(regulation of NIK/NF-kappaB signaling)|go:"GO:1902443"(negative regulation of ripoptosome assembly involved in necroptotic process)|go:"GO:1902523"(positive regulation of protein K63-linked ubiquitination)|go:"GO:1902524"(positive regulation of protein K48-linked ubiquitination)|go:"GO:1902527"(positive regulation of protein monoubiquitination)|go:"GO:2000116"(regulation of cysteine-type endopeptidase activity)|go:"GO:2000377"(regulation of reactive oxygen species metabolic process)|interpro:IPR001315(Caspase Recruitment)|interpro:IPR001370(Proteinase inhibitor I32, inhibitor of apoptosis)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011029(DEATH-like)|interpro:IPR041933|mint:Q13490|rcsb pdb:1QBH|rcsb pdb:2L9M|rcsb pdb:3D9T|rcsb pdb:3D9U|rcsb pdb:3M1D|rcsb pdb:3MUP|rcsb pdb:3OZ1|rcsb pdb:3T6P|rcsb pdb:3UW4|rcsb pdb:4EB9|rcsb pdb:4HY4|rcsb pdb:4HY5|rcsb pdb:4KMN|rcsb pdb:4LGE|rcsb pdb:4LGU|rcsb pdb:4MTI|rcsb pdb:4MU7|rcsb pdb:5M6N|rcsb pdb:6EXW|rcsb pdb:6HPR|rcsb pdb:6W74|rcsb pdb:6W7O|rcsb pdb:6W8I|reactome:R-HSA-111465|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-5213460|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5668541|reactome:R-HSA-5675482|reactome:R-HSA-5676594|reactome:R-HSA-5689880|reactome:R-HSA-937041|ensembl:ENSG00000110330(gene)|ensembl:ENST00000227758(transcript)|ensembl:ENST00000613397(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001741"(XY body)|go:"GO:0001890"(placenta development)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0016740"(transferase activity)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034121"(regulation of toll-like receptor signaling pathway)|go:"GO:0035631"(CD40 receptor complex)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0039535"(regulation of RIG-I signaling pathway)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)	refseq:NP_075206.1|sgd:S000007586|interpro:IPR002634(BolA-like protein)|interpro:IPR036065|ensemblfungi:YAL044W-A(gene)|ensemblfungi:YAL044W-A_mRNA(transcript)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0044572"([4Fe-4S] cluster assembly)|go:"GO:0106035"(protein maturation by [4Fe-4S] cluster transfer)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:FOikzyDyDtlv2l69i/WNDNq674A9606	rogid:9pYGPvGIU56X3neAXP8LQXxWfC4559292	intact-crc:2F962B0E31AB27FB|rigid:axSefRuPDtrVgBhaqjmLlfAFKg8	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P32502	uniprotkb:Q53EZ4	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	intact:EBI-747776|uniprotkb:Q32WF5|uniprotkb:Q3MV20|uniprotkb:Q5VY28|uniprotkb:Q6N034|ensembl:ENSP00000360540|uniprotkb:Q96H32|uniprotkb:Q9NVS7|uniprotkb:B2RDG8|intact:EBI-10173536|uniprotkb:D3DR37|intact:EBI-28973801	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:cep55_human(display_long)|uniprotkb:Up-regulated in colon cancer 6(gene name synonym)|uniprotkb:CEP55(gene name)|psi-mi:CEP55(display_short)|uniprotkb:URCC6(gene name synonym)|uniprotkb:C10orf3(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551844|imex:IM-24995-3532	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731	refseq:NP_001120654.1|refseq:NP_060601.3|ensembl:ENSG00000138180(gene)|ensembl:ENST00000371485(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0014066"(regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0030496"(midbody)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042802"(identical protein binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0061952"(midbody abscission)|go:"GO:0090543"(Flemming body)|go:"GO:1904888"(cranial skeletal system development)|interpro:IPR022008|interpro:IPR038926|mint:Q53EZ4|rcsb pdb:3E1R|rcsb pdb:3WUT|rcsb pdb:3WUU|rcsb pdb:3WUV|go:"GO:0005814"(centriole)|ensembl:ENSP00000360540|dip:DIP-44581N	-	crc64:A5409FAF1594854C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	rogid:tuo36vVb8ZgPDR81YjZFNEg559w9606	intact-crc:13B5441A15AE2A67|rigid:2kHflvspg2fhw+Zk3atP8GZBmTk	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q53EZ4	intact:EBI-11522371	intact:EBI-747776|uniprotkb:Q32WF5|uniprotkb:Q3MV20|uniprotkb:Q5VY28|uniprotkb:Q6N034|ensembl:ENSP00000360540|uniprotkb:Q96H32|uniprotkb:Q9NVS7|uniprotkb:B2RDG8|intact:EBI-10173536|uniprotkb:D3DR37|intact:EBI-28973801	-	psi-mi:cep55_human(display_long)|uniprotkb:Up-regulated in colon cancer 6(gene name synonym)|uniprotkb:CEP55(gene name)|psi-mi:CEP55(display_short)|uniprotkb:URCC6(gene name synonym)|uniprotkb:C10orf3(gene name synonym)	psi-mi:yjr003c(display_short)|psi-mi:EBI-11522371(display_long)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551840|imex:IM-24995-3531	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001120654.1|refseq:NP_060601.3|ensembl:ENSG00000138180(gene)|ensembl:ENST00000371485(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0014066"(regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0030496"(midbody)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042802"(identical protein binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0061952"(midbody abscission)|go:"GO:0090543"(Flemming body)|go:"GO:1904888"(cranial skeletal system development)|interpro:IPR022008|interpro:IPR038926|mint:Q53EZ4|rcsb pdb:3E1R|rcsb pdb:3WUT|rcsb pdb:3WUU|rcsb pdb:3WUV|go:"GO:0005814"(centriole)|ensembl:ENSP00000360540|dip:DIP-44581N	-	-	-	no-uniprot-update:	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:tuo36vVb8ZgPDR81YjZFNEg559w9606	rogid:dYGrrP3JnrXO2rj4v/nTT64la6A4932	intact-crc:D4F71D3FDC959974|rigid:Ziq/qA2vX/etQxiTQCosKuYngCs	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q53EZ4	uniprotkb:Q06411	intact:EBI-747776|uniprotkb:Q32WF5|uniprotkb:Q3MV20|uniprotkb:Q5VY28|uniprotkb:Q6N034|ensembl:ENSP00000360540|uniprotkb:Q96H32|uniprotkb:Q9NVS7|uniprotkb:B2RDG8|intact:EBI-10173536|uniprotkb:D3DR37|intact:EBI-28973801	intact:EBI-576|uniprotkb:D6VZ60|ensemblfungi:YLR424W	psi-mi:cep55_human(display_long)|uniprotkb:Up-regulated in colon cancer 6(gene name synonym)|uniprotkb:CEP55(gene name)|psi-mi:CEP55(display_short)|uniprotkb:URCC6(gene name synonym)|uniprotkb:C10orf3(gene name synonym)	psi-mi:sp382_yeast(display_long)|uniprotkb:NTR1(gene name synonym)|uniprotkb:YLR424W(locus name)|uniprotkb:SPP382(gene name)|psi-mi:SPP382(display_short)|uniprotkb:CCF8(gene name synonym)|uniprotkb:Suppressor of PRP38 protein 2(gene name synonym)|uniprotkb:Nineteen complex-related protein 1(gene name synonym)|uniprotkb:CLF1 complex factor 8(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551836|imex:IM-24995-3530	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001120654.1|refseq:NP_060601.3|ensembl:ENSG00000138180(gene)|ensembl:ENST00000371485(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0014066"(regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0030496"(midbody)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042802"(identical protein binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0061952"(midbody abscission)|go:"GO:0090543"(Flemming body)|go:"GO:1904888"(cranial skeletal system development)|interpro:IPR022008|interpro:IPR038926|mint:Q53EZ4|rcsb pdb:3E1R|rcsb pdb:3WUT|rcsb pdb:3WUU|rcsb pdb:3WUV|go:"GO:0005814"(centriole)|ensembl:ENSP00000360540|dip:DIP-44581N	refseq:NP_013528.1|sgd:S000004416|dip:DIP-1491N|mint:Q06411|ensemblfungi:YLR424W(gene)|ensemblfungi:YLR424W_mRNA(transcript)|go:"GO:0000349"(generation of catalytic spliceosome for first transesterification step)|go:"GO:0000390"(spliceosomal complex disassembly)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0071008"(U2-type post-mRNA release spliceosomal complex)|go:"GO:1904876"(negative regulation of DNA ligase activity)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR000467(D111/G-patch)|rcsb pdb:5Y88	-	-	crc64:9986B547B9582338	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:tuo36vVb8ZgPDR81YjZFNEg559w9606	rogid:HrG54vTE2zs7jxPSzi+9eeA23/k559292	intact-crc:E34683D8DB5EE41D|rigid:h0XN/2wUCVo5EFf2F1nVYCyhxCE	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q53EZ4	uniprotkb:Q07732	intact:EBI-747776|uniprotkb:Q32WF5|uniprotkb:Q3MV20|uniprotkb:Q5VY28|uniprotkb:Q6N034|ensembl:ENSP00000360540|uniprotkb:Q96H32|uniprotkb:Q9NVS7|uniprotkb:B2RDG8|intact:EBI-10173536|uniprotkb:D3DR37|intact:EBI-28973801	intact:EBI-33406|ensemblfungi:YDL239C|uniprotkb:D6VRB7	psi-mi:cep55_human(display_long)|uniprotkb:Up-regulated in colon cancer 6(gene name synonym)|uniprotkb:CEP55(gene name)|psi-mi:CEP55(display_short)|uniprotkb:URCC6(gene name synonym)|uniprotkb:C10orf3(gene name synonym)	psi-mi:ady3_yeast(display_long)|uniprotkb:YDL239C(locus name)|uniprotkb:ADY3(gene name)|psi-mi:ADY3(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551832|imex:IM-24995-3529	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001120654.1|refseq:NP_060601.3|ensembl:ENSG00000138180(gene)|ensembl:ENST00000371485(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0014066"(regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0030496"(midbody)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042802"(identical protein binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0061952"(midbody abscission)|go:"GO:0090543"(Flemming body)|go:"GO:1904888"(cranial skeletal system development)|interpro:IPR022008|interpro:IPR038926|mint:Q53EZ4|rcsb pdb:3E1R|rcsb pdb:3WUT|rcsb pdb:3WUU|rcsb pdb:3WUV|go:"GO:0005814"(centriole)|ensembl:ENSP00000360540|dip:DIP-44581N	refseq:NP_010042.2|sgd:S000002398|ensemblfungi:YDL239C(gene)|ensemblfungi:YDL239C_mRNA(transcript)|go:"GO:0000001"(mitochondrion inheritance)|go:"GO:0005628"(prospore membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0030435"(sporulation resulting in formation of a cellular spore)|go:"GO:0030476"(ascospore wall assembly)|go:"GO:0032120"(ascospore-type prospore membrane formation)|go:"GO:0051301"(cell division)|go:"GO:0070056"(prospore membrane leading edge)|interpro:IPR021750|mint:Q07732|dip:DIP-1811N	-	-	crc64:46F17474F30FD3D9	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:tuo36vVb8ZgPDR81YjZFNEg559w9606	rogid:Cmac2NLDdbBzVKnJfFricfeeX24559292	intact-crc:3A175A8B2030420F|rigid:6wOQ2W+NyTq4Z43Gtutq8hrUUEs	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q3E7B2	uniprotkb:O43765	intact:EBI-3680840|uniprotkb:D6VWB9|ensemblfungi:YJL062W-A	intact:EBI-347996|ensembl:ENSP00000221566|ensembl:ENSP00000503397|ensembl:ENSP00000504495|uniprotkb:Q9BTZ9|intact:EBI-1045243|uniprotkb:Q6FIA9|uniprotkb:D6W610	psi-mi:coa3_yeast(display_long)|uniprotkb:COA3(gene name)|psi-mi:COA3(display_short)|uniprotkb:COX25(gene name synonym)|uniprotkb:RRG10(gene name synonym)|uniprotkb:Required for respiratory growth protein 10(gene name synonym)|uniprotkb:YJL062W-A(locus name)|uniprotkb:Cytochrome c oxidase protein 25(gene name synonym)	psi-mi:sgta_human(display_long)|uniprotkb:SGTA(gene name)|psi-mi:SGTA(display_short)|uniprotkb:SGT(gene name synonym)|uniprotkb:Alpha-SGT(gene name synonym)|uniprotkb:Vpu-binding protein(gene name synonym)|uniprotkb:SGT1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551828|imex:IM-24995-3528	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	mint:Q3E7B2|sgd:S000007611|refseq:NP_076894.3|ensemblfungi:YJL062W-A(gene)|ensemblfungi:YJL062W-A_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0031305"(integral component of mitochondrial inner membrane)|go:"GO:0033617"(mitochondrial cytochrome c oxidase assembly)|go:"GO:0070130"(negative regulation of mitochondrial translation)|interpro:IPR041752	rcsb pdb:4CPG|rcsb pdb:4GOD|rcsb pdb:4GOE|rcsb pdb:4GOF|reactome:R-HSA-9609523|rcsb pdb:2VYI|ensembl:ENSG00000104969(gene)|ensembl:ENST00000221566(transcript)|ensembl:ENST00000676943(transcript)|ensembl:ENST00000677149(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072380"(TRC complex)|go:"GO:0098850"(extrinsic component of synaptic vesicle membrane)|go:"GO:1903070"(negative regulation of ER-associated ubiquitin-dependent protein catabolic process)|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)|go:"GO:1903646"(positive regulation of chaperone-mediated protein folding)|go:"GO:1904288"(BAT3 complex binding)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR032374|mint:O43765|refseq:XP_011526480.1|refseq:NP_003012.1	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:uBAPwV/LO79+3saLLV4gAWUQPnA559292	rogid:r/Cyj4UJk/cS8QdrbjhTZMPCigI9606	intact-crc:916593BAF5FE4C59|rigid:WHn9ozY9bPYuvwX4RxDe23MdmC4	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P11972	uniprotkb:Q53EZ4	intact:EBI-18232|uniprotkb:Q06207|uniprotkb:D6VZ86|ensemblfungi:YLR452C	intact:EBI-747776|uniprotkb:Q32WF5|uniprotkb:Q3MV20|uniprotkb:Q5VY28|uniprotkb:Q6N034|ensembl:ENSP00000360540|uniprotkb:Q96H32|uniprotkb:Q9NVS7|uniprotkb:B2RDG8|intact:EBI-10173536|uniprotkb:D3DR37|intact:EBI-28973801	psi-mi:sst2_yeast(display_long)|uniprotkb:SST2(gene name)|psi-mi:SST2(display_short)|uniprotkb:L9324.9(orf name)|uniprotkb:YLR452C(locus name)	psi-mi:cep55_human(display_long)|uniprotkb:Up-regulated in colon cancer 6(gene name synonym)|uniprotkb:CEP55(gene name)|psi-mi:CEP55(display_short)|uniprotkb:URCC6(gene name synonym)|uniprotkb:C10orf3(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551856|imex:IM-24995-3535	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013557.1|sgd:S000004444|ensemblfungi:YLR452C(gene)|ensemblfungi:YLR452C_mRNA(transcript)|go:"GO:0000754"(adaptation of signaling pathway by response to pheromone involved in conjugation with cellular fusion)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0009968"(negative regulation of signal transduction)|go:"GO:0035556"(intracellular signal transduction)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR036305|interpro:IPR036388|interpro:IPR036390|interpro:IPR016137(Regulator of G protein signalling superfamily)|dip:DIP-2354N|mint:P11972	refseq:NP_001120654.1|refseq:NP_060601.3|ensembl:ENSG00000138180(gene)|ensembl:ENST00000371485(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0014066"(regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0030496"(midbody)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042802"(identical protein binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0061952"(midbody abscission)|go:"GO:0090543"(Flemming body)|go:"GO:1904888"(cranial skeletal system development)|interpro:IPR022008|interpro:IPR038926|mint:Q53EZ4|rcsb pdb:3E1R|rcsb pdb:3WUT|rcsb pdb:3WUU|rcsb pdb:3WUV|go:"GO:0005814"(centriole)|ensembl:ENSP00000360540|dip:DIP-44581N	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:a452jzptv3MtejNfc+LDrwSFSks559292	rogid:tuo36vVb8ZgPDR81YjZFNEg559w9606	intact-crc:CD665A90E6E63F76|rigid:2CY9YiVxtRxh2T3VgAvA03Km7O0	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P35180	uniprotkb:Q53EZ4	intact:EBI-12522|uniprotkb:D6VUL4|ensemblfungi:YGR082W	intact:EBI-747776|uniprotkb:Q32WF5|uniprotkb:Q3MV20|uniprotkb:Q5VY28|uniprotkb:Q6N034|ensembl:ENSP00000360540|uniprotkb:Q96H32|uniprotkb:Q9NVS7|uniprotkb:B2RDG8|intact:EBI-10173536|uniprotkb:D3DR37|intact:EBI-28973801	psi-mi:tom20_yeast(display_long)|uniprotkb:MOM19(gene name synonym)|uniprotkb:YGR082W(locus name)|uniprotkb:TOM20(gene name)|psi-mi:TOM20(display_short)|uniprotkb:MAS20(gene name synonym)|uniprotkb:Mitochondrial 20 kDa outer membrane protein(gene name synonym)|uniprotkb:Translocase of outer membrane 20 kDa subunit(gene name synonym)|uniprotkb:Protein MAS20(gene name synonym)	psi-mi:cep55_human(display_long)|uniprotkb:Up-regulated in colon cancer 6(gene name synonym)|uniprotkb:CEP55(gene name)|psi-mi:CEP55(display_short)|uniprotkb:URCC6(gene name synonym)|uniprotkb:C10orf3(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551852|imex:IM-24995-3534	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YGR082W(gene)|ensemblfungi:YGR082W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005742"(mitochondrial outer membrane translocase complex)|go:"GO:0016031"(tRNA import into mitochondrion)|go:"GO:0030150"(protein import into mitochondrial matrix)|go:"GO:0030943"(mitochondrion targeting sequence binding)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|interpro:IPR002056(Protein import receptor MAS20)|interpro:IPR023392|refseq:NP_011596.1|sgd:S000003314|dip:DIP-2539N|mint:P35180	refseq:NP_001120654.1|refseq:NP_060601.3|ensembl:ENSG00000138180(gene)|ensembl:ENST00000371485(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0014066"(regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0030496"(midbody)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042802"(identical protein binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0061952"(midbody abscission)|go:"GO:0090543"(Flemming body)|go:"GO:1904888"(cranial skeletal system development)|interpro:IPR022008|interpro:IPR038926|mint:Q53EZ4|rcsb pdb:3E1R|rcsb pdb:3WUT|rcsb pdb:3WUU|rcsb pdb:3WUV|go:"GO:0005814"(centriole)|ensembl:ENSP00000360540|dip:DIP-44581N	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:7U00YLVWcaegWlJEKzGblv6STx4559292	rogid:tuo36vVb8ZgPDR81YjZFNEg559w9606	intact-crc:E04BD2D6651E2F9E|rigid:d0peQzDL8PgCsaXwaCi695W2e0Y	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P38340	uniprotkb:Q53EZ4	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-747776|uniprotkb:Q32WF5|uniprotkb:Q3MV20|uniprotkb:Q5VY28|uniprotkb:Q6N034|ensembl:ENSP00000360540|uniprotkb:Q96H32|uniprotkb:Q9NVS7|uniprotkb:B2RDG8|intact:EBI-10173536|uniprotkb:D3DR37|intact:EBI-28973801	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:cep55_human(display_long)|uniprotkb:Up-regulated in colon cancer 6(gene name synonym)|uniprotkb:CEP55(gene name)|psi-mi:CEP55(display_short)|uniprotkb:URCC6(gene name synonym)|uniprotkb:C10orf3(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551848|imex:IM-24995-3533	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F	refseq:NP_001120654.1|refseq:NP_060601.3|ensembl:ENSG00000138180(gene)|ensembl:ENST00000371485(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0014066"(regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0030496"(midbody)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042802"(identical protein binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0061952"(midbody abscission)|go:"GO:0090543"(Flemming body)|go:"GO:1904888"(cranial skeletal system development)|interpro:IPR022008|interpro:IPR038926|mint:Q53EZ4|rcsb pdb:3E1R|rcsb pdb:3WUT|rcsb pdb:3WUU|rcsb pdb:3WUV|go:"GO:0005814"(centriole)|ensembl:ENSP00000360540|dip:DIP-44581N	-	crc64:66699F37B0013088	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:tuo36vVb8ZgPDR81YjZFNEg559w9606	intact-crc:0CD65B06DAA44391|rigid:dnMfuhgSQScUNIvPg2emyYRhpSc	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P32502	uniprotkb:Q53G59	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	intact:EBI-740929|ensembl:ENSP00000356230|uniprotkb:A6NEN8|uniprotkb:B7Z7B8|uniprotkb:Q9HBX5	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:klh12_human(display_long)|uniprotkb:CUL3-interacting protein 1(gene name synonym)|uniprotkb:KLHL12(gene name)|psi-mi:KLHL12(display_short)|uniprotkb:C3IP1(gene name synonym)|uniprotkb:DKIR homolog(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551872|imex:IM-24995-3539	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731	go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048208"(COPII vesicle coating)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR017096(Kelch-like protein, gigaxonin)|mint:Q53G59|rcsb pdb:2VPJ|rcsb pdb:6TTK|rcsb pdb:6V7O|reactome:R-HSA-4641258|refseq:NP_067646.1|ensembl:ENSG00000117153(gene)|ensembl:ENST00000367261(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0014029"(neural crest formation)|go:"GO:0014032"(neural crest cell development)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0034451"(centriolar satellite)|refseq:NP_001289980.1|refseq:NP_001290038.1	-	crc64:A5409FAF1594854C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	rogid:C4I/Ys9vqNqfG61HsXRZhywP4vE9606	intact-crc:FC43050D58248914|rigid:QkZKqnQnfaRcRbHr7Uib0bBlOJ8	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q53EZ4	uniprotkb:P49089	intact:EBI-747776|uniprotkb:Q32WF5|uniprotkb:Q3MV20|uniprotkb:Q5VY28|uniprotkb:Q6N034|ensembl:ENSP00000360540|uniprotkb:Q96H32|uniprotkb:Q9NVS7|uniprotkb:B2RDG8|intact:EBI-10173536|uniprotkb:D3DR37|intact:EBI-28973801	intact:EBI-3043|uniprotkb:D6W4E2|ensemblfungi:YPR145W	psi-mi:cep55_human(display_long)|uniprotkb:Up-regulated in colon cancer 6(gene name synonym)|uniprotkb:CEP55(gene name)|psi-mi:CEP55(display_short)|uniprotkb:URCC6(gene name synonym)|uniprotkb:C10orf3(gene name synonym)	psi-mi:asns1_yeast(display_long)|uniprotkb:ASN1(gene name)|psi-mi:ASN1(display_short)|uniprotkb:YPR145W(locus name)|uniprotkb:P9659.3(orf name)|uniprotkb:Glutamine-dependent asparagine synthetase 1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551860|imex:IM-24995-3536	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001120654.1|refseq:NP_060601.3|ensembl:ENSG00000138180(gene)|ensembl:ENST00000371485(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0014066"(regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0030496"(midbody)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042802"(identical protein binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0061952"(midbody abscission)|go:"GO:0090543"(Flemming body)|go:"GO:1904888"(cranial skeletal system development)|interpro:IPR022008|interpro:IPR038926|mint:Q53EZ4|rcsb pdb:3E1R|rcsb pdb:3WUT|rcsb pdb:3WUU|rcsb pdb:3WUV|go:"GO:0005814"(centriole)|ensembl:ENSP00000360540|dip:DIP-44581N	refseq:NP_015471.1|sgd:S000006349|dip:DIP-3810N|reactome:R-SCE-8963693|ensemblfungi:YPR145W(gene)|ensemblfungi:YPR145W_mRNA(transcript)|go:"GO:0004066"("asparagine synthase (glutamine-hydrolyzing) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006529"(asparagine biosynthetic process)|go:"GO:0006541"(glutamine metabolic process)|go:"GO:0070981"(L-asparagine biosynthetic process)|interpro:IPR001962(Asparagine synthase)|interpro:IPR006426(Asparagine synthase, glutamine-hydrolyzing)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR017932|interpro:IPR029055|interpro:IPR033738	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:tuo36vVb8ZgPDR81YjZFNEg559w9606	rogid:jel8vvbk1/PZHmUs57fDe2ybZ3Q559292	intact-crc:3F089E6A705B73EC|rigid:VoacHHA6wqVGluBP+KxT9eZssmY	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P53953	uniprotkb:Q53G59	intact:EBI-17006|uniprotkb:D6W1D0|ensemblfungi:YNL049C	intact:EBI-740929|ensembl:ENSP00000356230|uniprotkb:A6NEN8|uniprotkb:B7Z7B8|uniprotkb:Q9HBX5	psi-mi:sfb2_yeast(display_long)|uniprotkb:SFB2(gene name)|psi-mi:SFB2(display_short)|uniprotkb:ISS1(gene name synonym)|uniprotkb:YNL049C(locus name)|uniprotkb:N2505(orf name)|uniprotkb:YNL2505C(orf name)|uniprotkb:SEC24-related protein 2(gene name synonym)	psi-mi:klh12_human(display_long)|uniprotkb:CUL3-interacting protein 1(gene name synonym)|uniprotkb:KLHL12(gene name)|psi-mi:KLHL12(display_short)|uniprotkb:C3IP1(gene name synonym)|uniprotkb:DKIR homolog(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551868|imex:IM-24995-3538	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YNL049C(gene)|ensemblfungi:YNL049C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0005048"(signal sequence binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:0090110"(COPII-coated vesicle cargo loading)|interpro:IPR006896(Sec23/Sec24 trunk region)|interpro:IPR006900(Sec23/Sec24 helical region)|interpro:IPR007123(Gelsolin region)|interpro:IPR012990(Sec23/Sec24 beta-sandwich)|interpro:IPR029006|interpro:IPR036174|interpro:IPR036175|interpro:IPR036180|interpro:IPR036465|interpro:IPR041742|reactome:R-SCE-204005|reactome:R-SCE-5694530|reactome:R-SCE-983170|interpro:IPR006895(Zinc finger, Sec23/Sec24-type)|refseq:NP_014349.1|sgd:S000004994|dip:DIP-4370N|mint:P53953	go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048208"(COPII vesicle coating)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR017096(Kelch-like protein, gigaxonin)|mint:Q53G59|rcsb pdb:2VPJ|rcsb pdb:6TTK|rcsb pdb:6V7O|reactome:R-HSA-4641258|refseq:NP_067646.1|ensembl:ENSG00000117153(gene)|ensembl:ENST00000367261(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0014029"(neural crest formation)|go:"GO:0014032"(neural crest cell development)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0034451"(centriolar satellite)|refseq:NP_001289980.1|refseq:NP_001290038.1	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:rG9Y9x8CduERmQuwFxUU/Z/wD1A559292	rogid:C4I/Ys9vqNqfG61HsXRZhywP4vE9606	intact-crc:6859D358D1E78D2B|rigid:f+ZAsu7g439pPlhuwB+oe75JgIs	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q53EZ4	uniprotkb:P35184	intact:EBI-747776|uniprotkb:Q32WF5|uniprotkb:Q3MV20|uniprotkb:Q5VY28|uniprotkb:Q6N034|ensembl:ENSP00000360540|uniprotkb:Q96H32|uniprotkb:Q9NVS7|uniprotkb:B2RDG8|intact:EBI-10173536|uniprotkb:D3DR37|intact:EBI-28973801	intact:EBI-17971|uniprotkb:D6VVU2|ensemblfungi:YIR012W	psi-mi:cep55_human(display_long)|uniprotkb:Up-regulated in colon cancer 6(gene name synonym)|uniprotkb:CEP55(gene name)|psi-mi:CEP55(display_short)|uniprotkb:URCC6(gene name synonym)|uniprotkb:C10orf3(gene name synonym)	psi-mi:sqt1_yeast(display_long)|uniprotkb:YIB12W(orf name)|uniprotkb:YIR012W(locus name)|uniprotkb:SQT1(gene name)|psi-mi:SQT1(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551864|imex:IM-24995-3537	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001120654.1|refseq:NP_060601.3|ensembl:ENSG00000138180(gene)|ensembl:ENST00000371485(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0014066"(regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0030496"(midbody)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042802"(identical protein binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0061952"(midbody abscission)|go:"GO:0090543"(Flemming body)|go:"GO:1904888"(cranial skeletal system development)|interpro:IPR022008|interpro:IPR038926|mint:Q53EZ4|rcsb pdb:3E1R|rcsb pdb:3WUT|rcsb pdb:3WUU|rcsb pdb:3WUV|go:"GO:0005814"(centriole)|ensembl:ENSP00000360540|dip:DIP-44581N	refseq:NP_012277.1|sgd:S000001451|ensemblfungi:YIR012W_mRNA(transcript)|ensemblfungi:YIR012W(gene)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|rcsb pdb:4ZOV|rcsb pdb:4ZOX|rcsb pdb:5AMS|dip:DIP-2508N|mint:P35184	-	-	crc64:981D566076B0C881	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:tuo36vVb8ZgPDR81YjZFNEg559w9606	rogid:u/Q5uAjR85ZD3op0nHiN20IVCLY559292	intact-crc:F99D15A3C5A85B5B|rigid:kLNE7nwqG2v/iClYBogzIR2poAo	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q06132	uniprotkb:Q53G59	intact:EBI-34377|uniprotkb:D6VYX6|ensemblfungi:YLR336C	intact:EBI-740929|ensembl:ENSP00000356230|uniprotkb:A6NEN8|uniprotkb:B7Z7B8|uniprotkb:Q9HBX5	psi-mi:sgd1_yeast(display_long)|uniprotkb:SGD1(gene name)|psi-mi:SGD1(display_short)|uniprotkb:YLR336C(locus name)	psi-mi:klh12_human(display_long)|uniprotkb:CUL3-interacting protein 1(gene name synonym)|uniprotkb:KLHL12(gene name)|psi-mi:KLHL12(display_short)|uniprotkb:C3IP1(gene name synonym)|uniprotkb:DKIR homolog(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551876|imex:IM-24995-3540	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013440.1|sgd:S000004328|mint:Q06132|dip:DIP-6333N|ensemblfungi:YLR336C(gene)|ensemblfungi:YLR336C_mRNA(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0006972"(hyperosmotic response)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0097078"(FAL1-SGD1 complex)|interpro:IPR003890(MIF4G-like, type 3)|interpro:IPR003891(Initiation factor eIF-4 gamma, MA3)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR016024(Armadillo-type fold)	go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048208"(COPII vesicle coating)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR017096(Kelch-like protein, gigaxonin)|mint:Q53G59|rcsb pdb:2VPJ|rcsb pdb:6TTK|rcsb pdb:6V7O|reactome:R-HSA-4641258|refseq:NP_067646.1|ensembl:ENSG00000117153(gene)|ensembl:ENST00000367261(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0014029"(neural crest formation)|go:"GO:0014032"(neural crest cell development)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0034451"(centriolar satellite)|refseq:NP_001289980.1|refseq:NP_001290038.1	-	crc64:8EEFDB8258407FF3	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:FxZCxGejbcvEs/J2h1HEaWeVZLQ559292	rogid:C4I/Ys9vqNqfG61HsXRZhywP4vE9606	intact-crc:2D9DB3C0BA7BAA14|rigid:uwuWNIj20Jz1K9Kbhna+kcAp4Ks	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q53HC0	uniprotkb:P53930	intact:EBI-719994|uniprotkb:Q9H697|uniprotkb:B3KNQ0|ensembl:ENSP00000238156|ensembl:ENSP00000488830	intact:EBI-28841|uniprotkb:Q6B1N1|uniprotkb:D6W173|ensemblfungi:YNL107W	psi-mi:ccd92_human(display_long)|uniprotkb:Limkain beta-2(gene name synonym)|uniprotkb:CCDC92(gene name)|psi-mi:CCDC92(display_short)	psi-mi:af9_yeast(display_long)|uniprotkb:N1966(orf name)|uniprotkb:YNL107W(locus name)|uniprotkb:YAF9(gene name)|psi-mi:YAF9(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551888|imex:IM-24995-3543	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_079416.1|ensembl:ENSG00000119242(gene)|ensembl:ENSG00000275035(gene)|ensembl:ENST00000238156(transcript)|ensembl:ENST00000632401(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR033224|interpro:IPR039496|interpro:IPR040370|mint:Q53HC0|refseq:NP_001291886.1|refseq:NP_001291887.1|refseq:NP_001291888.1|refseq:NP_001291889.1|refseq:NP_001291890.1|refseq:XP_005253681.1|refseq:XP_016875473.1	sgd:S000005051|refseq:NP_014292.3|dip:DIP-4347N|mint:P53930|ensemblfungi:YNL107W(gene)|ensemblfungi:YNL107W_mRNA(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000812"(Swr1 complex)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006348"|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0043486"(histone exchange)|interpro:IPR005033(YEATS)|interpro:IPR037989|interpro:IPR038704|rcsb pdb:3FK3|rcsb pdb:3RLS|rcsb pdb:6AXJ|reactome:R-SCE-674695|reactome:R-SCE-75955	-	-	crc64:1FE08F72942061D1	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:Iu/FzTqEpzn8N5WUTt1OwoKWxyc9606	rogid:oIwHCTPMu/kBEXUm82Yw5C0YYXw559292	intact-crc:1C85691C0E84553A|rigid:So1yakNwnIwuhyz0Ca1SI8vUTvg	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q53G59	uniprotkb:P53286	intact:EBI-740929|ensembl:ENSP00000356230|uniprotkb:A6NEN8|uniprotkb:B7Z7B8|uniprotkb:Q9HBX5	intact:EBI-3796|uniprotkb:D6VUS2|ensemblfungi:YGR142W	psi-mi:klh12_human(display_long)|uniprotkb:CUL3-interacting protein 1(gene name synonym)|uniprotkb:KLHL12(gene name)|psi-mi:KLHL12(display_short)|uniprotkb:C3IP1(gene name synonym)|uniprotkb:DKIR homolog(gene name synonym)	psi-mi:btn2_yeast(display_long)|uniprotkb:YGR142W(locus name)|uniprotkb:BTN2(gene name)|psi-mi:BTN2(display_short)|uniprotkb:Batten disease protein 2(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551884|imex:IM-24995-3542	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048208"(COPII vesicle coating)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR017096(Kelch-like protein, gigaxonin)|mint:Q53G59|rcsb pdb:2VPJ|rcsb pdb:6TTK|rcsb pdb:6V7O|reactome:R-HSA-4641258|refseq:NP_067646.1|ensembl:ENSG00000117153(gene)|ensembl:ENST00000367261(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0014029"(neural crest formation)|go:"GO:0014032"(neural crest cell development)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0034451"(centriolar satellite)|refseq:NP_001289980.1|refseq:NP_001290038.1	sgd:S000003374|refseq:NP_011658.3|dip:DIP-5534N|mint:P53286|ensemblfungi:YGR142W(gene)|ensemblfungi:YGR142W_mRNA(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005634"(nucleus)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006865"(amino acid transport)|go:"GO:0006885"(regulation of pH)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051087"(chaperone binding)|go:"GO:0140311"(protein sequestering activity)	-	-	crc64:E7AE1EB1E3612F3E	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:C4I/Ys9vqNqfG61HsXRZhywP4vE9606	rogid:Cu27xkwGMNyS4zLvUaG1UeH2mE0559292	intact-crc:9D0C38D8C30872DB|rigid:r2ZpBzJpduxdwbAVvF/LFDNgKak	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q53G59	uniprotkb:Q05021	intact:EBI-740929|ensembl:ENSP00000356230|uniprotkb:A6NEN8|uniprotkb:B7Z7B8|uniprotkb:Q9HBX5	intact:EBI-27490|uniprotkb:D6W052|ensemblfungi:YMR227C	psi-mi:klh12_human(display_long)|uniprotkb:CUL3-interacting protein 1(gene name synonym)|uniprotkb:KLHL12(gene name)|psi-mi:KLHL12(display_short)|uniprotkb:C3IP1(gene name synonym)|uniprotkb:DKIR homolog(gene name synonym)	psi-mi:taf7_yeast(display_long)|uniprotkb:TAF7(gene name)|psi-mi:TAF7(display_short)|uniprotkb:TAF67(gene name synonym)|uniprotkb:YMR227C(locus name)|uniprotkb:YM9959.09C(orf name)|uniprotkb:TBP-associated factor 7(gene name synonym)|uniprotkb:TBP-associated factor 67 kDa(gene name synonym)|uniprotkb:TAFII-67(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551880|imex:IM-24995-3541	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048208"(COPII vesicle coating)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR017096(Kelch-like protein, gigaxonin)|mint:Q53G59|rcsb pdb:2VPJ|rcsb pdb:6TTK|rcsb pdb:6V7O|reactome:R-HSA-4641258|refseq:NP_067646.1|ensembl:ENSG00000117153(gene)|ensembl:ENST00000367261(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0014029"(neural crest formation)|go:"GO:0014032"(neural crest cell development)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0034451"(centriolar satellite)|refseq:NP_001289980.1|refseq:NP_001290038.1	mint:Q05021|refseq:NP_013954.1|sgd:S000004840|dip:DIP-6818N|ensemblfungi:YMR227C(gene)|ensemblfungi:YMR227C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|interpro:IPR006751(TAFII55 protein conserved region)|interpro:IPR037817|rcsb pdb:4OY2|reactome:R-SCE-674695|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-76042	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:C4I/Ys9vqNqfG61HsXRZhywP4vE9606	rogid:VrnziwJxWKBtVBnyE3cijExq6/0559292	intact-crc:3CD7AC9CD42324E2|rigid:cpfrkul7pqqF7qDfIyZG1amofRI	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q5D1E8	uniprotkb:Q02793	intact:EBI-747793|uniprotkb:Q6I9Z1|uniprotkb:Q9H5P1|uniprotkb:D3DPT0|ensembl:ENSP00000362179	intact:EBI-17260|uniprotkb:D6VTU2|ensemblfungi:YGL213C	psi-mi:zc12a_human(display_long)|uniprotkb:MCPIP(gene name synonym)|uniprotkb:MCPIP1(gene name synonym)|uniprotkb:ZC3H12A(gene name)|psi-mi:ZC3H12A(display_short)|uniprotkb:Monocyte chemotactic protein-induced protein 1(gene name synonym)|uniprotkb:Regnase-1(gene name synonym)|uniprotkb:Zinc finger CCCH domain-containing protein 12A(gene name synonym)	psi-mi:ski8_yeast(display_long)|uniprotkb:YGL213C(locus name)|uniprotkb:SKI8(gene name)|psi-mi:SKI8(display_short)|uniprotkb:REC103(gene name synonym)|uniprotkb:Superkiller protein 8(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551892|imex:IM-24995-3544	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_079355.2|refseq:NP_001310479.1|ensembl:ENSG00000163874(gene)|ensembl:ENST00000373087(transcript)|go:"GO:0000294"(nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay)|go:"GO:0000932"(P-body)|go:"GO:0001525"(angiogenesis)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0002757"(immune response-activating signal transduction)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0004532"(exoribonuclease activity)|go:"GO:0004540"(ribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007399"(nervous system development)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010656"(negative regulation of muscle cell apoptotic process)|go:"GO:0010884"(positive regulation of lipid storage)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0030154"(cell differentiation)|go:"GO:0030867"(rough endoplasmic reticulum membrane)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032691"(negative regulation of interleukin-1 beta production)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035198"(miRNA binding)|go:"GO:0035613"(RNA stem-loop binding)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042406"(extrinsic component of endoplasmic reticulum membrane)|go:"GO:0043022"(ribosome binding)|go:"GO:0043031"(negative regulation of macrophage activation)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0044828"(negative regulation by host of viral genome replication)|go:"GO:0045019"(negative regulation of nitric oxide biosynthetic process)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051607"(defense response to virus)|go:"GO:0055118"(negative regulation of cardiac muscle contraction)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0090501"(RNA phosphodiester bond hydrolysis)|go:"GO:0090502"(RNA phosphodiester bond hydrolysis, endonucleolytic)|go:"GO:0098586"(cellular response to virus)|go:"GO:1900016"(negative regulation of cytokine production involved in inflammatory response)|go:"GO:1900119"(positive regulation of execution phase of apoptosis)|go:"GO:1901223"(negative regulation of NIK/NF-kappaB signaling)|go:"GO:1903003"(positive regulation of protein deubiquitination)|go:"GO:1903799"(negative regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1903936"(cellular response to sodium arsenite)|go:"GO:1904637"(cellular response to ionomycin)|go:"GO:1990869"(cellular response to chemokine)|go:"GO:2000320"(negative regulation of T-helper 17 cell differentiation)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|go:"GO:2000627"(positive regulation of miRNA catabolic process)|interpro:IPR021869|interpro:IPR040546|interpro:IPR040757|rcsb pdb:3V32|rcsb pdb:3V33|rcsb pdb:3V34|go:"GO:1900745"(positive regulation of p38MAPK cascade)	refseq:NP_011302.1|sgd:S000003181|ensemblfungi:YGL213C(gene)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034622"|go:"GO:0051607"(defense response to virus)|go:"GO:0055087"(Ski complex)|go:"GO:0065004"(protein-DNA complex assembly)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|rcsb pdb:1S4U|rcsb pdb:1SQ9|rcsb pdb:4BUJ|rcsb pdb:5MC6|reactome:R-SCE-429958|reactome:R-SCE-674695|reactome:R-SCE-75955|ensemblfungi:YGL213C_mRNA(transcript)|dip:DIP-1653N|mint:Q02793	-	-	crc64:C5E7B9D2268F9727	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:3FqqH/XrYjHaa5oJpPXvfYwHKCQ9606	rogid:6K6FJYcctdlT1321Nv6pOnQPwq8559292	intact-crc:FF51085762BD35E4|rigid:BYi2vr6auPKAMD8M263RLfI4o+4	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q5JR59-3	uniprotkb:P28004	intact:EBI-11522433|ensembl:ENSP00000370186	intact:EBI-20640|uniprotkb:D6VPI6|ensemblfungi:YAL032C	psi-mi:q5jr59-3(display_long)|uniprotkb:MTUS2(gene name)|psi-mi:MTUS2(display_short)|uniprotkb:CAZIP(gene name synonym)|uniprotkb:Cardiac zipper protein(gene name synonym)|uniprotkb:KIAA0774(gene name synonym)|uniprotkb:Microtubule plus-end tracking protein TIP150(gene name synonym)|uniprotkb:TIP150(gene name synonym)	psi-mi:prp45_yeast(display_long)|uniprotkb:YAL032C(locus name)|uniprotkb:PRP45(gene name)|psi-mi:PRP45(display_short)|uniprotkb:FUN20(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551936|imex:IM-24995-3555	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000132938(gene)|ensembl:ENST00000380808(transcript)|intact:EBI-742948(isoform-parent)|uniprotkb:Q5JR59-3(isoform-parent)	refseq:NP_009370.1|sgd:S000000030|ensemblfungi:YAL032C(gene)|ensemblfungi:YAL032C_mRNA(transcript)|go:"GO:0000350"(generation of catalytic spliceosome for second transesterification step)|go:"GO:0005634"(nucleus)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|interpro:IPR004015(SKIP/SNW)|interpro:IPR017862|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|dip:DIP-2774N|mint:P28004	-	isoform-comment:No experimental confirmation available.	crc64:FE5A724186D7FE84	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:npId9tC7VoLN/jteoBiRbSYChPs9606	rogid:qoHF1UsO3k+JOTOfigSuy2P84/k559292	intact-crc:F6956985EA3C93E5|rigid:+4ZFzEaiSQIi/mKLMudoTNTyewE	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P32902	uniprotkb:Q5JR59-3	intact:EBI-16248|ensemblfungi:YHL004W|uniprotkb:D3DKR0	intact:EBI-11522433|ensembl:ENSP00000370186	psi-mi:rt04_yeast(display_long)|uniprotkb:MRP4(gene name)|psi-mi:MRP4(display_short)|uniprotkb:MRP4A(gene name synonym)|uniprotkb:Mitochondrial small ribosomal subunit protein uS2m(gene name synonym)|uniprotkb:YHL004W(locus name)	psi-mi:q5jr59-3(display_long)|uniprotkb:MTUS2(gene name)|psi-mi:MTUS2(display_short)|uniprotkb:CAZIP(gene name synonym)|uniprotkb:Cardiac zipper protein(gene name synonym)|uniprotkb:KIAA0774(gene name synonym)|uniprotkb:Microtubule plus-end tracking protein TIP150(gene name synonym)|uniprotkb:TIP150(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551940|imex:IM-24995-3556	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YHL004W(gene)|ensemblfungi:YHL004W_mRNA(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR001865(Ribosomal protein S2)|interpro:IPR005706(Ribosomal protein S2, bacterial-type)|interpro:IPR018130|interpro:IPR023591|rcsb pdb:5MRC|rcsb pdb:5MRE|rcsb pdb:5MRF|refseq:NP_011859.1|sgd:S000000996|dip:DIP-5035N|mint:P32902	ensembl:ENSG00000132938(gene)|ensembl:ENST00000380808(transcript)|intact:EBI-742948(isoform-parent)|uniprotkb:Q5JR59-3(isoform-parent)	-	crc64:81A1CB33134BC559	isoform-comment:No experimental confirmation available.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:BlL3W6HUN+uAKF/AxwlV1zT5YZQ559292	rogid:npId9tC7VoLN/jteoBiRbSYChPs9606	intact-crc:D34C9E15E3F0CF74|rigid:SUqmciFNzecgze196/COIEQtPY0	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P40455	uniprotkb:Q5JR59-3	intact:EBI-25274|uniprotkb:D6VVD5|ensemblfungi:YIL152W	intact:EBI-11522433|ensembl:ENSP00000370186	psi-mi:yip2_yeast(display_long)|uniprotkb:YIL152W(locus name)	psi-mi:q5jr59-3(display_long)|uniprotkb:MTUS2(gene name)|psi-mi:MTUS2(display_short)|uniprotkb:CAZIP(gene name synonym)|uniprotkb:Cardiac zipper protein(gene name synonym)|uniprotkb:KIAA0774(gene name synonym)|uniprotkb:Microtubule plus-end tracking protein TIP150(gene name synonym)|uniprotkb:TIP150(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551944|imex:IM-24995-3557	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000001414|refseq:NP_012114.1|mint:P40455|dip:DIP-2047N|ensemblfungi:YIL152W(gene)|ensemblfungi:YIL152W_mRNA(transcript)	ensembl:ENSG00000132938(gene)|ensembl:ENST00000380808(transcript)|intact:EBI-742948(isoform-parent)|uniprotkb:Q5JR59-3(isoform-parent)	-	crc64:07550E3F491F53A8	isoform-comment:No experimental confirmation available.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:t5hCm1ck6kpFUxpEd8CsyLrHbEw559292	rogid:npId9tC7VoLN/jteoBiRbSYChPs9606	intact-crc:0EA928A735FB88D7|rigid:rDuZDZJuGb65exhgQM2kW3j5YMI	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q5JR59-3	uniprotkb:P40454	intact:EBI-11522433|ensembl:ENSP00000370186	intact:EBI-25278|uniprotkb:D6VVD4|ensemblfungi:YIL153W	psi-mi:q5jr59-3(display_long)|uniprotkb:MTUS2(gene name)|psi-mi:MTUS2(display_short)|uniprotkb:CAZIP(gene name synonym)|uniprotkb:Cardiac zipper protein(gene name synonym)|uniprotkb:KIAA0774(gene name synonym)|uniprotkb:Microtubule plus-end tracking protein TIP150(gene name synonym)|uniprotkb:TIP150(gene name synonym)	psi-mi:ptpa1_yeast(display_long)|uniprotkb:YIL153W(locus name)|uniprotkb:RRD1(gene name)|psi-mi:RRD1(display_short)|uniprotkb:NCS1(gene name synonym)|uniprotkb:YPA1(gene name synonym)|uniprotkb:Peptidyl-prolyl cis-trans isomerase PTPA-1(gene name synonym)|uniprotkb:Phosphotyrosyl phosphatase activator 1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551932|imex:IM-24995-3554	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000132938(gene)|ensembl:ENST00000380808(transcript)|intact:EBI-742948(isoform-parent)|uniprotkb:Q5JR59-3(isoform-parent)	refseq:NP_012113.1|sgd:S000001415|mint:P40454|dip:DIP-5663N|ensemblfungi:YIL153W(gene)|ensemblfungi:YIL153W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006914"(autophagy)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008160"(protein tyrosine phosphatase activator activity)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0043618"(regulation of transcription from RNA polymerase II promoter in response to stress)|interpro:IPR004327(Phosphotyrosyl phosphatase activator, PTPA)|interpro:IPR037218|interpro:IPR043170|rcsb pdb:2IXO|rcsb pdb:2IXP	-	isoform-comment:No experimental confirmation available.	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:npId9tC7VoLN/jteoBiRbSYChPs9606	rogid:It2q8WlpmvLEZ1fqpRF5Fypw9Q4559292	intact-crc:DACA11954EBF8D5D|rigid:63HnY7CBz4Rqs48lh7DgOXN3Gxw	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q5JR59-3	uniprotkb:P40302	intact:EBI-11522433|ensembl:ENSP00000370186	intact:EBI-13955|ensemblfungi:YMR314W|uniprotkb:D6W0E1	psi-mi:q5jr59-3(display_long)|uniprotkb:MTUS2(gene name)|psi-mi:MTUS2(display_short)|uniprotkb:CAZIP(gene name synonym)|uniprotkb:Cardiac zipper protein(gene name synonym)|uniprotkb:KIAA0774(gene name synonym)|uniprotkb:Microtubule plus-end tracking protein TIP150(gene name synonym)|uniprotkb:TIP150(gene name synonym)	psi-mi:psa6_yeast(display_long)|uniprotkb:PRE5(gene name)|psi-mi:PRE5(display_short)|uniprotkb:YMR314W(locus name)|uniprotkb:YM9924.06(orf name)|uniprotkb:Proteasome component PRE5(gene name synonym)|uniprotkb:Macropain subunit PRE5(gene name synonym)|uniprotkb:Proteinase YSCE subunit PRE5(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit PRE5(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551928|imex:IM-24995-3553	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000132938(gene)|ensembl:ENST00000380808(transcript)|intact:EBI-742948(isoform-parent)|uniprotkb:Q5JR59-3(isoform-parent)	rcsb pdb:4Y8T|rcsb pdb:4Y8U|rcsb pdb:4Y9Y|rcsb pdb:4Y9Z|rcsb pdb:4YA0|rcsb pdb:4YA1|rcsb pdb:4YA2|rcsb pdb:4YA3|rcsb pdb:4YA4|rcsb pdb:4YA5|rcsb pdb:4Y7X|rcsb pdb:4Y7Y|rcsb pdb:4Y80|rcsb pdb:4Y81|rcsb pdb:4Y82|rcsb pdb:4Y84|rcsb pdb:4Y8G|rcsb pdb:4Y8H|rcsb pdb:4Y8I|rcsb pdb:4Y8J|rcsb pdb:4Y8K|rcsb pdb:4Y8L|rcsb pdb:4Y8M|rcsb pdb:4Y8N|rcsb pdb:4Y8O|rcsb pdb:4Y8P|rcsb pdb:4Y8Q|rcsb pdb:4Y8R|rcsb pdb:4Y8S|rcsb pdb:5FG7|rcsb pdb:5FG9|rcsb pdb:5FGA|rcsb pdb:4YA7|rcsb pdb:4YA9|rcsb pdb:4Z1L|rcsb pdb:5A5B|rcsb pdb:5AHJ|rcsb pdb:5BOU|rcsb pdb:5BXL|rcsb pdb:5BXN|rcsb pdb:5CGF|rcsb pdb:5CGG|rcsb pdb:5CGH|rcsb pdb:5CGI|rcsb pdb:5CZ4|rcsb pdb:5CZ5|rcsb pdb:5CZ6|rcsb pdb:5CZ7|rcsb pdb:5CZ8|rcsb pdb:5CZ9|rcsb pdb:5CZA|rcsb pdb:5D0S|rcsb pdb:5D0T|rcsb pdb:5D0V|rcsb pdb:5D0W|rcsb pdb:5D0X|rcsb pdb:5D0Z|rcsb pdb:5DKI|rcsb pdb:5DKJ|rcsb pdb:5FGD|rcsb pdb:3HYE|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:3MG0|rcsb pdb:3MG4|rcsb pdb:3MG6|rcsb pdb:3MG7|rcsb pdb:3MG8|rcsb pdb:3NZJ|rcsb pdb:3NZW|rcsb pdb:3NZX|rcsb pdb:3OEU|rcsb pdb:3OEV|rcsb pdb:3OKJ|rcsb pdb:3SDI|rcsb pdb:3SDK|rcsb pdb:3SHJ|rcsb pdb:3TDD|rcsb pdb:3UN4|rcsb pdb:3UN8|rcsb pdb:3WXR|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:4EU2|rcsb pdb:4FZC|rcsb pdb:4FZG|rcsb pdb:4G4S|rcsb pdb:4GK7|rcsb pdb:4HNP|rcsb pdb:4HRC|rcsb pdb:4HRD|rcsb pdb:4INR|rcsb pdb:4INT|rcsb pdb:4INU|rcsb pdb:4J70|rcsb pdb:4JSQ|rcsb pdb:4JSU|rcsb pdb:4JT0|rcsb pdb:4LQI|rcsb pdb:4LTC|rcsb pdb:4NNN|rcsb pdb:4NNW|rcsb pdb:4NO1|rcsb pdb:4NO6|rcsb pdb:4NO8|rcsb pdb:4NO9|rcsb pdb:5FGE|rcsb pdb:5FGF|rcsb pdb:5FGG|rcsb pdb:5FGH|rcsb pdb:5FGI|rcsb pdb:5FHS|rcsb pdb:5JHR|rcsb pdb:5JHS|rcsb pdb:5L52|rcsb pdb:5L54|rcsb pdb:5L55|rcsb pdb:5L5A|rcsb pdb:5L5B|rcsb pdb:5L5D|rcsb pdb:5L5E|rcsb pdb:5L5F|rcsb pdb:5L5H|rcsb pdb:5L5I|rcsb pdb:5L5J|rcsb pdb:5L5O|rcsb pdb:5L5P|rcsb pdb:5L5Q|rcsb pdb:5L5R|rcsb pdb:4Q1S|rcsb pdb:4QBY|rcsb pdb:4QLQ|rcsb pdb:4QLS|rcsb pdb:4QLT|rcsb pdb:4QLU|rcsb pdb:4QLV|rcsb pdb:4QUX|rcsb pdb:4QUY|rcsb pdb:4QV0|rcsb pdb:4QV1|rcsb pdb:4QV3|rcsb pdb:4QV4|rcsb pdb:4QV5|rcsb pdb:4QV6|rcsb pdb:4QV7|rcsb pdb:4QV8|rcsb pdb:4QV9|rcsb pdb:4QVL|ensemblfungi:YMR314W(gene)|ensemblfungi:YMR314W_mRNA(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0042175"(nuclear outer membrane-endoplasmic reticulum membrane network)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR035144|rcsb pdb:1FNT|rcsb pdb:1G0U|rcsb pdb:1G65|rcsb pdb:1JD2|rcsb pdb:1RYP|rcsb pdb:1Z7Q|rcsb pdb:2F16|rcsb pdb:2FAK|rcsb pdb:2GPL|rcsb pdb:2ZCY|rcsb pdb:3BDM|rcsb pdb:3D29|rcsb pdb:3DY3|rcsb pdb:3DY4|rcsb pdb:3E47|rcsb pdb:3GPJ|rcsb pdb:3GPT|rcsb pdb:3GPW|rcsb pdb:4QVM|rcsb pdb:4QVN|rcsb pdb:4QVP|rcsb pdb:4QVQ|rcsb pdb:4QVV|rcsb pdb:4QVW|rcsb pdb:4QVY|rcsb pdb:4QW0|rcsb pdb:4QW1|rcsb pdb:4QW3|rcsb pdb:4QW4|rcsb pdb:4QW5|rcsb pdb:4QW6|rcsb pdb:4QW7|rcsb pdb:4QWF|rcsb pdb:4QWG|rcsb pdb:4QWI|rcsb pdb:4QWJ|rcsb pdb:4QWK|rcsb pdb:4QWL|rcsb pdb:4QWR|rcsb pdb:4QWS|rcsb pdb:4QWU|rcsb pdb:4QWX|rcsb pdb:4QXJ|rcsb pdb:4QZ0|rcsb pdb:4QZ1|rcsb pdb:4QZ2|rcsb pdb:4QZ3|rcsb pdb:4QZ4|rcsb pdb:4QZ5|rcsb pdb:4QZ6|rcsb pdb:4QZ7|rcsb pdb:4QZW|rcsb pdb:4QZX|rcsb pdb:4QZZ|rcsb pdb:4R00|rcsb pdb:4R02|rcsb pdb:4R17|rcsb pdb:4R18|rcsb pdb:4RUR|rcsb pdb:4V7O|rcsb pdb:4X6Z|rcsb pdb:4Y69|rcsb pdb:4Y6A|rcsb pdb:4Y6V|rcsb pdb:4Y6Z|rcsb pdb:4Y70|rcsb pdb:4Y74|rcsb pdb:4Y75|rcsb pdb:4Y77|rcsb pdb:4Y78|rcsb pdb:4Y7W|rcsb pdb:5LTT|rcsb pdb:5M2B|rcsb pdb:5MP9|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5NIF|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6G7F|rcsb pdb:6G8M|rcsb pdb:6G8N|rcsb pdb:6GOP|rcsb pdb:6H39|rcsb pdb:6HTB|rcsb pdb:6HTC|rcsb pdb:6HTD|rcsb pdb:6HTP|rcsb pdb:6HTR|rcsb pdb:6HUB|rcsb pdb:6HUC|rcsb pdb:6HUQ|rcsb pdb:6HUU|rcsb pdb:6HUV|rcsb pdb:6HV3|rcsb pdb:6HV4|rcsb pdb:6HV5|rcsb pdb:6HV7|rcsb pdb:6HVA|rcsb pdb:6HVR|rcsb pdb:6HVS|rcsb pdb:6HVT|rcsb pdb:6HVU|rcsb pdb:6HVV|rcsb pdb:5L5S|rcsb pdb:5L5T|rcsb pdb:5L5U|rcsb pdb:5L5V|rcsb pdb:5L5W|rcsb pdb:5L5X|rcsb pdb:5L5Y|rcsb pdb:5L5Z|rcsb pdb:5L60|rcsb pdb:5L61|rcsb pdb:5L62|rcsb pdb:5L63|rcsb pdb:5L64|rcsb pdb:5L65|rcsb pdb:5L66|rcsb pdb:5L67|rcsb pdb:5L68|rcsb pdb:5L69|rcsb pdb:5L6A|rcsb pdb:5L6B|rcsb pdb:5L6C|rcsb pdb:5LAI|rcsb pdb:5LAJ|rcsb pdb:6HVW|rcsb pdb:6HVX|rcsb pdb:6HVY|rcsb pdb:6HW0|rcsb pdb:6HW3|rcsb pdb:6HW4|rcsb pdb:6HW5|rcsb pdb:6HW6|rcsb pdb:6HW7|rcsb pdb:6HW8|rcsb pdb:6HW9|rcsb pdb:6HWA|rcsb pdb:6HWB|rcsb pdb:6HWC|rcsb pdb:6HWD|rcsb pdb:6HWE|rcsb pdb:6HWF|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2X|rcsb pdb:6J30|rcsb pdb:6ZOU|rcsb pdb:6ZP6|rcsb pdb:6ZP8|rcsb pdb:7LS5|rcsb pdb:7LS6|rcsb pdb:7LSX|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|rcsb pdb:6J2Q|refseq:NP_014045.1|sgd:S000004931|mint:P40302|dip:DIP-1528N	-	isoform-comment:No experimental confirmation available.	crc64:C43CBCC1C6B9E39E	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:npId9tC7VoLN/jteoBiRbSYChPs9606	rogid:C9GPb0JAklkBz0t/YYqRMNEiQss559292	intact-crc:7C48C06B4D7141E8|rigid:VE5JD2ppecB/NGSKdKwKlvM1j3o	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q5JR59-3	uniprotkb:P38744	intact:EBI-11522433|ensembl:ENSP00000370186	intact:EBI-13396|uniprotkb:D3DKR5|ensemblfungi:YHL018W	psi-mi:q5jr59-3(display_long)|uniprotkb:MTUS2(gene name)|psi-mi:MTUS2(display_short)|uniprotkb:CAZIP(gene name synonym)|uniprotkb:Cardiac zipper protein(gene name synonym)|uniprotkb:KIAA0774(gene name synonym)|uniprotkb:Microtubule plus-end tracking protein TIP150(gene name synonym)|uniprotkb:TIP150(gene name synonym)	psi-mi:phs_yeast(display_long)|uniprotkb:4-alpha-hydroxy-tetrahydropterin dehydratase(gene name synonym)|uniprotkb:Pterin carbinolamine dehydratase(gene name synonym)|uniprotkb:YHL018W(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551924|imex:IM-24995-3552	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000132938(gene)|ensembl:ENST00000380808(transcript)|intact:EBI-742948(isoform-parent)|uniprotkb:Q5JR59-3(isoform-parent)	refseq:NP_011845.1|sgd:S000001010|interpro:IPR036428|interpro:IPR001533(Transcriptional coactivator/pterin dehydratase)|ensemblfungi:YHL018W(gene)|ensemblfungi:YHL018W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0008124"(4-alpha-hydroxytetrahydrobiopterin dehydratase activity)|dip:DIP-1872N|reactome:R-SCE-8964208	-	isoform-comment:No experimental confirmation available.	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:npId9tC7VoLN/jteoBiRbSYChPs9606	rogid:7+JuLX1wFw/tkE4NcSCTK62b4DU559292	intact-crc:90740A865A3A42D2|rigid:OqlY1umJIVGHXTYTVzd2M3kGP9k	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q08204	uniprotkb:Q5JR59-3	intact:EBI-34125|uniprotkb:D6W231|ensemblfungi:YOL034W	intact:EBI-11522433|ensembl:ENSP00000370186	psi-mi:smc5_yeast(display_long)|uniprotkb:SMC5(gene name)|psi-mi:SMC5(display_short)|uniprotkb:YOL034W(locus name)	psi-mi:q5jr59-3(display_long)|uniprotkb:MTUS2(gene name)|psi-mi:MTUS2(display_short)|uniprotkb:CAZIP(gene name synonym)|uniprotkb:Cardiac zipper protein(gene name synonym)|uniprotkb:KIAA0774(gene name synonym)|uniprotkb:Microtubule plus-end tracking protein TIP150(gene name synonym)|uniprotkb:TIP150(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551920|imex:IM-24995-3551	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014608.1|sgd:S000005394|mint:Q08204|dip:DIP-1979N|ensemblfungi:YOL034W(gene)|ensemblfungi:YOL034W_mRNA(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000725"(recombinational repair)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006281"(DNA repair)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0016925"(protein sumoylation)|go:"GO:0030915"(Smc5-Smc6 complex)|go:"GO:0051304"(chromosome separation)|go:"GO:0071139"(resolution of recombination intermediates)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR027131|interpro:IPR027417|rcsb pdb:3HTK|reactome:R-SCE-3108214	ensembl:ENSG00000132938(gene)|ensembl:ENST00000380808(transcript)|intact:EBI-742948(isoform-parent)|uniprotkb:Q5JR59-3(isoform-parent)	-	crc64:6752B96438CFB549	isoform-comment:No experimental confirmation available.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:7EBoBNiTfotgfzhZ2+a+PcQTAqc559292	rogid:npId9tC7VoLN/jteoBiRbSYChPs9606	intact-crc:90C3181810F96AFF|rigid:5FCJttU5dvY+BGiAtowtRs3KLuQ	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P39946	uniprotkb:Q5JR59-3	intact:EBI-12838|uniprotkb:D6W2W9|ensemblfungi:YOR269W	intact:EBI-11522433|ensembl:ENSP00000370186	psi-mi:lis1_yeast(display_long)|uniprotkb:PAC1(gene name)|psi-mi:PAC1(display_short)|uniprotkb:nudF homolog(gene name synonym)|uniprotkb:LIS1(gene name synonym)|uniprotkb:Lissencephaly-1 homolog(gene name synonym)|uniprotkb:YOR269W(locus name)	psi-mi:q5jr59-3(display_long)|uniprotkb:MTUS2(gene name)|psi-mi:MTUS2(display_short)|uniprotkb:CAZIP(gene name synonym)|uniprotkb:Cardiac zipper protein(gene name synonym)|uniprotkb:KIAA0774(gene name synonym)|uniprotkb:Microtubule plus-end tracking protein TIP150(gene name synonym)|uniprotkb:TIP150(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551916|imex:IM-24995-3550	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YOR269W(gene)|ensemblfungi:YOR269W_mRNA(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007097"(nuclear migration)|go:"GO:0030473"(nuclear migration along microtubule)|go:"GO:0031023"(microtubule organizing center organization)|go:"GO:0042802"(identical protein binding)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0051012"(microtubule sliding)|go:"GO:0051301"(cell division)|go:"GO:0070840"(dynein complex binding)|go:"GO:1903033"(positive regulation of microtubule plus-end binding)|go:"GO:2000574"(obsolete regulation of microtubule motor activity)|go:"GO:2000582"(obsolete positive regulation of microtubule motor activity, plus-end-directed)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR017252(Dynein regulator)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|interpro:IPR037190|rcsb pdb:5VH9|rcsb pdb:5VLJ|refseq:NP_014912.1|sgd:S000005795|mint:P39946|dip:DIP-1485N	ensembl:ENSG00000132938(gene)|ensembl:ENST00000380808(transcript)|intact:EBI-742948(isoform-parent)|uniprotkb:Q5JR59-3(isoform-parent)	-	crc64:E667E4BA7602FB3B	isoform-comment:No experimental confirmation available.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:tyU5fR5V8csklk2QqAQHt3Mmz7c559292	rogid:npId9tC7VoLN/jteoBiRbSYChPs9606	intact-crc:E97FAC2AA24EB0B2|rigid:mcPqwa1Q/HPtG6yn9wOQcWws6DA	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P32571	uniprotkb:Q5JR59-3	intact:EBI-19840|uniprotkb:D6VS55|ensemblfungi:YDR069C	intact:EBI-11522433|ensembl:ENSP00000370186	psi-mi:ubp4_yeast(display_long)|uniprotkb:DOA4(gene name)|psi-mi:DOA4(display_short)|uniprotkb:MUT4(gene name synonym)|uniprotkb:SSV7(gene name synonym)|uniprotkb:YDR069C(locus name)|uniprotkb:YD9609.23C(orf name)|uniprotkb:YD8554.02C(orf name)|uniprotkb:D4270(orf name)|uniprotkb:NPI2(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 4(gene name synonym)|uniprotkb:Deubiquitinating enzyme 4(gene name synonym)|uniprotkb:Vacuole biogenesis protein SSV7(gene name synonym)|uniprotkb:Ubiquitin thioesterase 4(gene name synonym)|uniprotkb:DOS1(gene name synonym)|uniprotkb:UBP4(gene name synonym)	psi-mi:q5jr59-3(display_long)|uniprotkb:MTUS2(gene name)|psi-mi:MTUS2(display_short)|uniprotkb:CAZIP(gene name synonym)|uniprotkb:Cardiac zipper protein(gene name synonym)|uniprotkb:KIAA0774(gene name synonym)|uniprotkb:Microtubule plus-end tracking protein TIP150(gene name synonym)|uniprotkb:TIP150(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551912|imex:IM-24995-3549	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002476|ensemblfungi:YDR069C(gene)|ensemblfungi:YDR069C_mRNA(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005739"(mitochondrion)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0010992"(ubiquitin recycling)|go:"GO:0010995"(free ubiquitin chain depolymerization)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0031902"(late endosome membrane)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0070676"(intralumenal vesicle formation)|go:"GO:1904669"(ATP export)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR001763(Rhodanese-like)|interpro:IPR018200|interpro:IPR028889|interpro:IPR036873|interpro:IPR038765|refseq:NP_010354.3|dip:DIP-5298N|mint:P32571	ensembl:ENSG00000132938(gene)|ensembl:ENST00000380808(transcript)|intact:EBI-742948(isoform-parent)|uniprotkb:Q5JR59-3(isoform-parent)	-	-	isoform-comment:No experimental confirmation available.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:UTBSWmpygyxo1ygxp/sQ8wgqnMo559292	rogid:npId9tC7VoLN/jteoBiRbSYChPs9606	intact-crc:BF444188D12357CE|rigid:mEWh4UkwNk8Pil//vX8dQyZ9SAA	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q5JR59-3	uniprotkb:P32502	intact:EBI-11522433|ensembl:ENSP00000370186	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:q5jr59-3(display_long)|uniprotkb:MTUS2(gene name)|psi-mi:MTUS2(display_short)|uniprotkb:CAZIP(gene name synonym)|uniprotkb:Cardiac zipper protein(gene name synonym)|uniprotkb:KIAA0774(gene name synonym)|uniprotkb:Microtubule plus-end tracking protein TIP150(gene name synonym)|uniprotkb:TIP150(gene name synonym)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551908|imex:IM-24995-3548	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000132938(gene)|ensembl:ENST00000380808(transcript)|intact:EBI-742948(isoform-parent)|uniprotkb:Q5JR59-3(isoform-parent)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731	-	isoform-comment:No experimental confirmation available.	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:npId9tC7VoLN/jteoBiRbSYChPs9606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:D402D95583468F6B|rigid:TOLzTALWlWRNyacE8+VOm+bAeFA	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q5D1E8	uniprotkb:P20095	intact:EBI-747793|uniprotkb:Q6I9Z1|uniprotkb:Q9H5P1|uniprotkb:D3DPT0|ensembl:ENSP00000362179	intact:EBI-13820|ensemblfungi:YNR011C|uniprotkb:D6W1I6	psi-mi:zc12a_human(display_long)|uniprotkb:MCPIP(gene name synonym)|uniprotkb:MCPIP1(gene name synonym)|uniprotkb:ZC3H12A(gene name)|psi-mi:ZC3H12A(display_short)|uniprotkb:Monocyte chemotactic protein-induced protein 1(gene name synonym)|uniprotkb:Regnase-1(gene name synonym)|uniprotkb:Zinc finger CCCH domain-containing protein 12A(gene name synonym)	psi-mi:prp2_yeast(display_long)|uniprotkb:PRP2(gene name)|psi-mi:PRP2(display_short)|uniprotkb:RNA2(gene name synonym)|uniprotkb:YNR011C(locus name)|uniprotkb:N2048(orf name)|uniprotkb:Pre-mRNA-processing protein 2(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551900|imex:IM-24995-3546	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_079355.2|refseq:NP_001310479.1|ensembl:ENSG00000163874(gene)|ensembl:ENST00000373087(transcript)|go:"GO:0000294"(nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay)|go:"GO:0000932"(P-body)|go:"GO:0001525"(angiogenesis)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0002757"(immune response-activating signal transduction)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0004532"(exoribonuclease activity)|go:"GO:0004540"(ribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007399"(nervous system development)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010656"(negative regulation of muscle cell apoptotic process)|go:"GO:0010884"(positive regulation of lipid storage)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0030154"(cell differentiation)|go:"GO:0030867"(rough endoplasmic reticulum membrane)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032691"(negative regulation of interleukin-1 beta production)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035198"(miRNA binding)|go:"GO:0035613"(RNA stem-loop binding)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042406"(extrinsic component of endoplasmic reticulum membrane)|go:"GO:0043022"(ribosome binding)|go:"GO:0043031"(negative regulation of macrophage activation)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0044828"(negative regulation by host of viral genome replication)|go:"GO:0045019"(negative regulation of nitric oxide biosynthetic process)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051607"(defense response to virus)|go:"GO:0055118"(negative regulation of cardiac muscle contraction)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0090501"(RNA phosphodiester bond hydrolysis)|go:"GO:0090502"(RNA phosphodiester bond hydrolysis, endonucleolytic)|go:"GO:0098586"(cellular response to virus)|go:"GO:1900016"(negative regulation of cytokine production involved in inflammatory response)|go:"GO:1900119"(positive regulation of execution phase of apoptosis)|go:"GO:1901223"(negative regulation of NIK/NF-kappaB signaling)|go:"GO:1903003"(positive regulation of protein deubiquitination)|go:"GO:1903799"(negative regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1903936"(cellular response to sodium arsenite)|go:"GO:1904637"(cellular response to ionomycin)|go:"GO:1990869"(cellular response to chemokine)|go:"GO:2000320"(negative regulation of T-helper 17 cell differentiation)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|go:"GO:2000627"(positive regulation of miRNA catabolic process)|interpro:IPR021869|interpro:IPR040546|interpro:IPR040757|rcsb pdb:3V32|rcsb pdb:3V33|rcsb pdb:3V34|go:"GO:1900745"(positive regulation of p38MAPK cascade)	refseq:NP_014408.1|sgd:S000005294|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|rcsb pdb:5GM6|rcsb pdb:5LQW|rcsb pdb:7DCO|rcsb pdb:7DCP|rcsb pdb:7DCQ|rcsb pdb:7DCR|rcsb pdb:7DD3|go:"GO:0140603"(obsolete ATP hydrolysis activity)|ensemblfungi:YNR011C(gene)|ensemblfungi:YNR011C_mRNA(transcript)|go:"GO:0000349"(generation of catalytic spliceosome for first transesterification step)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0008186"(ATP-dependent activity, acting on RNA)|go:"GO:0034247"(snoRNA splicing)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|mint:P20095|dip:DIP-3961N	-	-	crc64:7EB3E1EE93215F57	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:3FqqH/XrYjHaa5oJpPXvfYwHKCQ9606	rogid:wfkc/eidpcEF1HlVabj2p/arPiY559292	intact-crc:114C94D77CE11435|rigid:1XVpLofLTzJg9RI/NFUp2L3C13M	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q5D1E8	uniprotkb:P53829	intact:EBI-747793|uniprotkb:Q6I9Z1|uniprotkb:Q9H5P1|uniprotkb:D3DPT0|ensembl:ENSP00000362179	intact:EBI-28306|uniprotkb:D6W0Q5|ensemblfungi:YNL288W	psi-mi:zc12a_human(display_long)|uniprotkb:MCPIP(gene name synonym)|uniprotkb:MCPIP1(gene name synonym)|uniprotkb:ZC3H12A(gene name)|psi-mi:ZC3H12A(display_short)|uniprotkb:Monocyte chemotactic protein-induced protein 1(gene name synonym)|uniprotkb:Regnase-1(gene name synonym)|uniprotkb:Zinc finger CCCH domain-containing protein 12A(gene name synonym)	psi-mi:caf40_yeast(display_long)|uniprotkb:YNL288W(locus name)|uniprotkb:N0540(orf name)|uniprotkb:40 kDa CCR4-associated factor(gene name synonym)|uniprotkb:CAF40(gene name)|psi-mi:CAF40(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551896|imex:IM-24995-3545	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_079355.2|refseq:NP_001310479.1|ensembl:ENSG00000163874(gene)|ensembl:ENST00000373087(transcript)|go:"GO:0000294"(nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay)|go:"GO:0000932"(P-body)|go:"GO:0001525"(angiogenesis)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0002757"(immune response-activating signal transduction)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0004532"(exoribonuclease activity)|go:"GO:0004540"(ribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007399"(nervous system development)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010656"(negative regulation of muscle cell apoptotic process)|go:"GO:0010884"(positive regulation of lipid storage)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0030154"(cell differentiation)|go:"GO:0030867"(rough endoplasmic reticulum membrane)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032691"(negative regulation of interleukin-1 beta production)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035198"(miRNA binding)|go:"GO:0035613"(RNA stem-loop binding)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042406"(extrinsic component of endoplasmic reticulum membrane)|go:"GO:0043022"(ribosome binding)|go:"GO:0043031"(negative regulation of macrophage activation)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0044828"(negative regulation by host of viral genome replication)|go:"GO:0045019"(negative regulation of nitric oxide biosynthetic process)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051607"(defense response to virus)|go:"GO:0055118"(negative regulation of cardiac muscle contraction)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0090501"(RNA phosphodiester bond hydrolysis)|go:"GO:0090502"(RNA phosphodiester bond hydrolysis, endonucleolytic)|go:"GO:0098586"(cellular response to virus)|go:"GO:1900016"(negative regulation of cytokine production involved in inflammatory response)|go:"GO:1900119"(positive regulation of execution phase of apoptosis)|go:"GO:1901223"(negative regulation of NIK/NF-kappaB signaling)|go:"GO:1903003"(positive regulation of protein deubiquitination)|go:"GO:1903799"(negative regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1903936"(cellular response to sodium arsenite)|go:"GO:1904637"(cellular response to ionomycin)|go:"GO:1990869"(cellular response to chemokine)|go:"GO:2000320"(negative regulation of T-helper 17 cell differentiation)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|go:"GO:2000627"(positive regulation of miRNA catabolic process)|interpro:IPR021869|interpro:IPR040546|interpro:IPR040757|rcsb pdb:3V32|rcsb pdb:3V33|rcsb pdb:3V34|go:"GO:1900745"(positive regulation of p38MAPK cascade)	refseq:NP_014111.1|sgd:S000005232|dip:DIP-1995N|mint:P53829|ensemblfungi:YNL288W(gene)|ensemblfungi:YNL288W_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR007216(Cell differentiation, Rcd1-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:4CV5	-	-	crc64:F3DBABE6AD3C7F3C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:3FqqH/XrYjHaa5oJpPXvfYwHKCQ9606	rogid:etuSSgFGQOcgxPDexEXUqQg6H5s559292	intact-crc:FF44B266F8DA01B6|rigid:9PZ5wbTppPaR8VCtVhxWGZzUepo	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q5JR59-3	uniprotkb:Q06630	intact:EBI-11522433|ensembl:ENSP00000370186	intact:EBI-36794|uniprotkb:D6VSS5|ensemblfungi:YDR296W	psi-mi:q5jr59-3(display_long)|uniprotkb:MTUS2(gene name)|psi-mi:MTUS2(display_short)|uniprotkb:CAZIP(gene name synonym)|uniprotkb:Cardiac zipper protein(gene name synonym)|uniprotkb:KIAA0774(gene name synonym)|uniprotkb:Microtubule plus-end tracking protein TIP150(gene name synonym)|uniprotkb:TIP150(gene name synonym)	psi-mi:mhr1_yeast(display_long)|uniprotkb:MHR1(gene name)|psi-mi:MHR1(display_short)|uniprotkb:YDR296W(locus name)|uniprotkb:Cross-linked transcription component 1(gene name synonym)|uniprotkb:XTC1(gene name synonym)|uniprotkb:Mitochondrial large ribosomal subunit protein mL67(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551904|imex:IM-24995-3547	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000132938(gene)|ensembl:ENST00000380808(transcript)|intact:EBI-742948(isoform-parent)|uniprotkb:Q5JR59-3(isoform-parent)	sgd:S000002704|refseq:NP_010582.3|mint:Q06630|dip:DIP-5727N|ensemblfungi:YDR296W(gene)|ensemblfungi:YDR296W_mRNA(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0000150"(DNA strand exchange activity)|go:"GO:0003677"(DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0006310"(DNA recombination)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0032543"(mitochondrial translation)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0090297"(positive regulation of mitochondrial DNA replication)|interpro:IPR024629|rcsb pdb:3J6B|rcsb pdb:5MRC|rcsb pdb:5MRE|rcsb pdb:5MRF	-	isoform-comment:No experimental confirmation available.	crc64:F26903A4814091C4	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:npId9tC7VoLN/jteoBiRbSYChPs9606	rogid:eA38S7UNOpP716XSQ0zzhYm2TqA559292	intact-crc:E1BA03BB4ADC9E22|rigid:FVW3iio5D5kaMySpXHM8SU1Py1A	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q5JST6	uniprotkb:Q12354	intact:EBI-2349927|uniprotkb:Q9H653|uniprotkb:Q5JST8|uniprotkb:Q68DK4|uniprotkb:Q8NEI0|intact:EBI-28971886|ensembl:ENSP00000404232	intact:EBI-37732|uniprotkb:D6VYB6|ensemblfungi:YLR118C	psi-mi:efhc2_human(display_long)|uniprotkb:EFHC2(gene name)|psi-mi:EFHC2(display_short)	psi-mi:apth1_yeast(display_long)|uniprotkb:L2955(orf name)|uniprotkb:YLR118C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551980|imex:IM-24995-3566	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000404232|refseq:NP_079460.2|ensembl:ENSG00000183690(gene)|ensembl:ENST00000420999(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005930"(axoneme)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0060285"(cilium-dependent cell motility)|go:"GO:0072686"(mitotic spindle)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR006602(Region of unknown function DM10)|interpro:IPR011992(EF-Hand type)|interpro:IPR040193|rcsb pdb:2Z13|rcsb pdb:2Z14	refseq:NP_013219.1|sgd:S000004108|reactome:R-SCE-203615|dip:DIP-2830N|reactome:R-SCE-9648002|ensemblfungi:YLR118C(gene)|ensemblfungi:YLR118C_mRNA(transcript)|go:"GO:0002084"(protein depalmitoylation)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0008474"("palmitoyl-(protein) hydrolase activity")|go:"GO:0035601"(protein deacylation)|go:"GO:0052689"(carboxylic ester hydrolase activity)|interpro:IPR003140(Phospholipase/carboxylesterase)|interpro:IPR029058	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:O1XriQSkLcYkk7H7AlanQ1FKIBY9606	rogid:z4WO9062CHwiLV2c1/+N6zn0AEE559292	intact-crc:4F1D8D3B0AB66EDF|rigid:ERsx6GWfLx/Ylwy0BOdDl5+83hc	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q5JR59-3	uniprotkb:P40958	intact:EBI-11522433|ensembl:ENSP00000370186	intact:EBI-10362|ensemblfungi:YJL030W|uniprotkb:D6VWF2	psi-mi:q5jr59-3(display_long)|uniprotkb:MTUS2(gene name)|psi-mi:MTUS2(display_short)|uniprotkb:CAZIP(gene name synonym)|uniprotkb:Cardiac zipper protein(gene name synonym)|uniprotkb:KIAA0774(gene name synonym)|uniprotkb:Microtubule plus-end tracking protein TIP150(gene name synonym)|uniprotkb:TIP150(gene name synonym)	psi-mi:mad2_yeast(display_long)|uniprotkb:MAD2(gene name)|psi-mi:MAD2(display_short)|uniprotkb:J1256(orf name)|uniprotkb:YJL030W(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551948|imex:IM-24995-3558	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000132938(gene)|ensembl:ENST00000380808(transcript)|intact:EBI-742948(isoform-parent)|uniprotkb:Q5JR59-3(isoform-parent)	sgd:S000003567|ensemblfungi:YJL030W(gene)|ensemblfungi:YJL030W_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0033597"(mitotic checkpoint complex)|go:"GO:0044774"(mitotic DNA integrity checkpoint signaling)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051301"(cell division)|go:"GO:0051312"(chromosome decondensation)|go:"GO:1902499"(positive regulation of protein autoubiquitination)|interpro:IPR003511(DNA-binding HORMA)|interpro:IPR027097|interpro:IPR036570|reactome:R-SCE-141405|reactome:R-SCE-141430|refseq:NP_012504.3|dip:DIP-815N|mint:P40958	-	isoform-comment:No experimental confirmation available.	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:npId9tC7VoLN/jteoBiRbSYChPs9606	rogid:0pxFckODTcklkGn+JcczltjSHRU559292	intact-crc:CEC505C2A9739AE5|rigid:GcG2aYAqQEdnpQZa1GwLlJzofBc	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P47041	uniprotkb:Q5JR59-3	intact:EBI-25889|uniprotkb:D6VWC4|ensemblfungi:YJL058C	intact:EBI-11522433|ensembl:ENSP00000370186	psi-mi:bit61_yeast(display_long)|uniprotkb:YJL058C(locus name)|uniprotkb:J1141(orf name)|uniprotkb:61 kDa binding partner of TOR2 protein(gene name synonym)|uniprotkb:BIT61(gene name)|psi-mi:BIT61(display_short)	psi-mi:q5jr59-3(display_long)|uniprotkb:MTUS2(gene name)|psi-mi:MTUS2(display_short)|uniprotkb:CAZIP(gene name synonym)|uniprotkb:Cardiac zipper protein(gene name synonym)|uniprotkb:KIAA0774(gene name synonym)|uniprotkb:Microtubule plus-end tracking protein TIP150(gene name synonym)|uniprotkb:TIP150(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551952|imex:IM-24995-3559	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012477.1|sgd:S000003594|dip:DIP-1444N|reactome:R-SCE-1257604|reactome:R-SCE-389357|reactome:R-SCE-5218920|ensemblfungi:YJL058C(gene)|ensemblfungi:YJL058C_mRNA(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005737"(cytoplasm)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0031932"(TORC2 complex)|go:"GO:0038203"(TORC2 signaling)|go:"GO:0071944"(cell periphery)|interpro:IPR013745(HbrB-like)|reactome:R-SCE-6804757	ensembl:ENSG00000132938(gene)|ensembl:ENST00000380808(transcript)|intact:EBI-742948(isoform-parent)|uniprotkb:Q5JR59-3(isoform-parent)	-	crc64:99F0F96840311F4B	isoform-comment:No experimental confirmation available.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:H+zcKwbWL90wsmvD9TfWYmEbRwM559292	rogid:npId9tC7VoLN/jteoBiRbSYChPs9606	intact-crc:F081C3450FF944D4|rigid:hyXrfFtNznuLrOumgbEL9f+b/iI	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P23293	uniprotkb:Q5JR59-3	intact:EBI-17078|ensemblfungi:YPR161C|uniprotkb:D6W4G2	intact:EBI-11522433|ensembl:ENSP00000370186	psi-mi:bur1_yeast(display_long)|uniprotkb:SGV1(gene name)|psi-mi:SGV1(display_short)|uniprotkb:BUR1(gene name synonym)|uniprotkb:YPR161C(locus name)|uniprotkb:P9584.8(orf name)|uniprotkb:Bypass UAS requirement protein 1(gene name synonym)|uniprotkb:Suppressor of GPA1-Vall50 mutation protein 1(gene name synonym)	psi-mi:q5jr59-3(display_long)|uniprotkb:MTUS2(gene name)|psi-mi:MTUS2(display_short)|uniprotkb:CAZIP(gene name synonym)|uniprotkb:Cardiac zipper protein(gene name synonym)|uniprotkb:KIAA0774(gene name synonym)|uniprotkb:Microtubule plus-end tracking protein TIP150(gene name synonym)|uniprotkb:TIP150(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551956|imex:IM-24995-3560	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR011009(Protein kinase-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-SCE-674695|reactome:R-SCE-6796648|reactome:R-SCE-6807505|reactome:R-SCE-75955|reactome:R-SCE-9018519|refseq:NP_015487.1|sgd:S000006365|ensemblfungi:YPR161C(gene)|ensemblfungi:YPR161C_mRNA(transcript)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0030332"(cyclin binding)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|dip:DIP-5916N|mint:P23293	ensembl:ENSG00000132938(gene)|ensembl:ENST00000380808(transcript)|intact:EBI-742948(isoform-parent)|uniprotkb:Q5JR59-3(isoform-parent)	-	crc64:CC9034A4B10A510E	isoform-comment:No experimental confirmation available.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:yPWc2VNSXjSxoSgzeiu7Jy5S1C0559292	rogid:npId9tC7VoLN/jteoBiRbSYChPs9606	intact-crc:4369A55796C01F3C|rigid:/q/RGhuOXkmYRC6xFcgGn2RsXgQ	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
intact:EBI-11522371	uniprotkb:Q5JR59-3	-	intact:EBI-11522433|ensembl:ENSP00000370186	psi-mi:yjr003c(display_short)|psi-mi:EBI-11522371(display_long)	psi-mi:q5jr59-3(display_long)|uniprotkb:MTUS2(gene name)|psi-mi:MTUS2(display_short)|uniprotkb:CAZIP(gene name synonym)|uniprotkb:Cardiac zipper protein(gene name synonym)|uniprotkb:KIAA0774(gene name synonym)|uniprotkb:Microtubule plus-end tracking protein TIP150(gene name synonym)|uniprotkb:TIP150(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551960|imex:IM-24995-3561	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSG00000132938(gene)|ensembl:ENST00000380808(transcript)|intact:EBI-742948(isoform-parent)|uniprotkb:Q5JR59-3(isoform-parent)	-	no-uniprot-update:	isoform-comment:No experimental confirmation available.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:dYGrrP3JnrXO2rj4v/nTT64la6A4932	rogid:npId9tC7VoLN/jteoBiRbSYChPs9606	intact-crc:0F550670F3A5A242|rigid:/VcQ18j57lmRaJc5lZLRViDVBO8	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P48837	uniprotkb:Q5JR59-3	intact:EBI-12324|ensemblfungi:YGR119C|uniprotkb:D6VUQ0	intact:EBI-11522433|ensembl:ENSP00000370186	psi-mi:nup57_yeast(display_long)|uniprotkb:NUP57(gene name)|psi-mi:NUP57(display_short)|uniprotkb:YGR119C(locus name)|uniprotkb:G6320(orf name)|uniprotkb:Nuclear pore protein NUP57(gene name synonym)	psi-mi:q5jr59-3(display_long)|uniprotkb:MTUS2(gene name)|psi-mi:MTUS2(display_short)|uniprotkb:CAZIP(gene name synonym)|uniprotkb:Cardiac zipper protein(gene name synonym)|uniprotkb:KIAA0774(gene name synonym)|uniprotkb:Microtubule plus-end tracking protein TIP150(gene name synonym)|uniprotkb:TIP150(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551964|imex:IM-24995-3562	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YGR119C(gene)|ensemblfungi:YGR119C_mRNA(transcript)|go:"GO:0005643"(nuclear pore)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036228"(protein localization to nuclear inner membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0051028"(mRNA transport)|interpro:IPR024864|interpro:IPR025574|interpro:IPR025712|refseq:NP_011634.1|sgd:S000003351|mint:P48837|dip:DIP-866N	ensembl:ENSG00000132938(gene)|ensembl:ENST00000380808(transcript)|intact:EBI-742948(isoform-parent)|uniprotkb:Q5JR59-3(isoform-parent)	-	-	isoform-comment:No experimental confirmation available.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:ultDTflWHx7n/y2FrlWFf+lBKmw559292	rogid:npId9tC7VoLN/jteoBiRbSYChPs9606	intact-crc:AFE4144899C3F51D|rigid:qPpBrX3s1J3WortwGo2VBLAlPzI	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q5JR59-3	uniprotkb:Q12056	intact:EBI-11522433|ensembl:ENSP00000370186	intact:EBI-30488|uniprotkb:D6W2T0|ensemblfungi:YOR226C	psi-mi:q5jr59-3(display_long)|uniprotkb:MTUS2(gene name)|psi-mi:MTUS2(display_short)|uniprotkb:CAZIP(gene name synonym)|uniprotkb:Cardiac zipper protein(gene name synonym)|uniprotkb:KIAA0774(gene name synonym)|uniprotkb:Microtubule plus-end tracking protein TIP150(gene name synonym)|uniprotkb:TIP150(gene name synonym)	psi-mi:isu2_yeast(display_long)|uniprotkb:Iron sulfur cluster scaffold protein 2(gene name synonym)|uniprotkb:ISU2(gene name)|psi-mi:ISU2(display_short)|uniprotkb:NUA2(gene name synonym)|uniprotkb:YOR226C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551968|imex:IM-24995-3563	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000132938(gene)|ensembl:ENST00000380808(transcript)|intact:EBI-742948(isoform-parent)|uniprotkb:Q5JR59-3(isoform-parent)	sgd:S000005752|refseq:NP_014869.3|dip:DIP-4123N|ensemblfungi:YOR226C(gene)|ensemblfungi:YOR226C_mRNA(transcript)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005737"(cytoplasm)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR002871(NIF system FeS cluster assembly, NifU, N-terminal)|interpro:IPR011339(ISC system FeS cluster assembly, IscU scaffold)	-	isoform-comment:No experimental confirmation available.	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:npId9tC7VoLN/jteoBiRbSYChPs9606	rogid:e4qx7ic8wpO6cTHGl73je/JVzMY559292	intact-crc:E659D2F91BAB9EB0|rigid:ib6N2MWFX4QO5wg3LquH2AFjOl0	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q03654	uniprotkb:Q5JR59-3	intact:EBI-476|uniprotkb:Q6B1D8|ensemblfungi:YMR213W|uniprotkb:D6W038	intact:EBI-11522433|ensembl:ENSP00000370186	psi-mi:cef1_yeast(display_long)|uniprotkb:CEF1(gene name)|psi-mi:CEF1(display_short)|uniprotkb:YMR213W(locus name)|uniprotkb:YM8261.07(orf name)|uniprotkb:NTC85(gene name synonym)|uniprotkb:PRP nineteen-associated complex protein 85(gene name synonym)|uniprotkb:PRP19-associated complex protein 85(gene name synonym)	psi-mi:q5jr59-3(display_long)|uniprotkb:MTUS2(gene name)|psi-mi:MTUS2(display_short)|uniprotkb:CAZIP(gene name synonym)|uniprotkb:Cardiac zipper protein(gene name synonym)|uniprotkb:KIAA0774(gene name synonym)|uniprotkb:Microtubule plus-end tracking protein TIP150(gene name synonym)|uniprotkb:TIP150(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551972|imex:IM-24995-3564	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013940.1|sgd:S000004826|ensemblfungi:YMR213W(gene)|ensemblfungi:YMR213W_mRNA(transcript)|go:"GO:0000350"(generation of catalytic spliceosome for second transesterification step)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000974"(Prp19 complex)|go:"GO:0003677"(DNA binding)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017930|interpro:IPR021786|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|rcsb pdb:7DCO|dip:DIP-1113N|mint:Q03654	ensembl:ENSG00000132938(gene)|ensembl:ENST00000380808(transcript)|intact:EBI-742948(isoform-parent)|uniprotkb:Q5JR59-3(isoform-parent)	-	crc64:A4C417A8B330EA9C	isoform-comment:No experimental confirmation available.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:AsbV7RtNk+8mCzLk2wZYqbULOFg559292	rogid:npId9tC7VoLN/jteoBiRbSYChPs9606	intact-crc:451FA25A43407846|rigid:bQMRsdSCaKABsIAcLn26s2IoIpM	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P47041	uniprotkb:Q5JST6	intact:EBI-25889|uniprotkb:D6VWC4|ensemblfungi:YJL058C	intact:EBI-2349927|uniprotkb:Q9H653|uniprotkb:Q5JST8|uniprotkb:Q68DK4|uniprotkb:Q8NEI0|intact:EBI-28971886|ensembl:ENSP00000404232	psi-mi:bit61_yeast(display_long)|uniprotkb:YJL058C(locus name)|uniprotkb:J1141(orf name)|uniprotkb:61 kDa binding partner of TOR2 protein(gene name synonym)|uniprotkb:BIT61(gene name)|psi-mi:BIT61(display_short)	psi-mi:efhc2_human(display_long)|uniprotkb:EFHC2(gene name)|psi-mi:EFHC2(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551976|imex:IM-24995-3565	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012477.1|sgd:S000003594|dip:DIP-1444N|reactome:R-SCE-1257604|reactome:R-SCE-389357|reactome:R-SCE-5218920|ensemblfungi:YJL058C(gene)|ensemblfungi:YJL058C_mRNA(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005737"(cytoplasm)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0031932"(TORC2 complex)|go:"GO:0038203"(TORC2 signaling)|go:"GO:0071944"(cell periphery)|interpro:IPR013745(HbrB-like)|reactome:R-SCE-6804757	ensembl:ENSP00000404232|refseq:NP_079460.2|ensembl:ENSG00000183690(gene)|ensembl:ENST00000420999(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005930"(axoneme)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0060285"(cilium-dependent cell motility)|go:"GO:0072686"(mitotic spindle)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR006602(Region of unknown function DM10)|interpro:IPR011992(EF-Hand type)|interpro:IPR040193|rcsb pdb:2Z13|rcsb pdb:2Z14	-	crc64:99F0F96840311F4B	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:H+zcKwbWL90wsmvD9TfWYmEbRwM559292	rogid:O1XriQSkLcYkk7H7AlanQ1FKIBY9606	intact-crc:8A5B92B7C0CA4F7C|rigid:04DO0Pw4mEQB80QbSnV9DtvHa8A	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q06616	uniprotkb:Q5SW96	intact:EBI-36065|uniprotkb:D6W4H5|ensemblfungi:YPR174C	intact:EBI-747813|uniprotkb:A2BHI5|uniprotkb:Q6TQS9|uniprotkb:Q8N2Y0|uniprotkb:Q9UFI9|intact:EBI-28971912|ensembl:ENSP00000363458	psi-mi:yp174_yeast(display_long)|uniprotkb:YPR174C(locus name)	psi-mi:arh_human(display_long)|uniprotkb:Autosomal recessive hypercholesterolemia protein(gene name synonym)|uniprotkb:LDLRAP1(gene name)|psi-mi:LDLRAP1(display_short)|uniprotkb:ARH(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552008|imex:IM-24995-3573	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015500.1|sgd:S000006378|dip:DIP-3800N|ensemblfungi:YPR174C(gene)|ensemblfungi:YPR174C_mRNA(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034399"(nuclear periphery)|interpro:IPR013743(Nap binding NBP1, fungi)	ensembl:ENSP00000363458|refseq:NP_056442.2|go:"GO:0042982"(amyloid precursor protein metabolic process)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0055037"(recycling endosome)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0090118"(receptor-mediated endocytosis involved in cholesterol transport)|go:"GO:0090205"(positive regulation of cholesterol metabolic process)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905581"(positive regulation of low-density lipoprotein particle clearance)|go:"GO:1905602"(positive regulation of receptor-mediated endocytosis involved in cholesterol transport)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|rcsb pdb:2G30|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8964026|reactome:R-HSA-8964038|ensembl:ENSG00000157978(gene)|ensembl:ENST00000374338(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005883"(neurofilament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030276"(clathrin binding)|go:"GO:0030301"(cholesterol transport)|go:"GO:0030424"(axon)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031623"(receptor internalization)|go:"GO:0034383"(low-density lipoprotein particle clearance)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0035612"(AP-2 adaptor complex binding)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0035650"(AP-1 adaptor complex binding)|go:"GO:0042632"(cholesterol homeostasis)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:R+7auDlEsOm+VR9gJ1jZsF3ST88559292	rogid:dtBWLcVpVD/R0aKQZr9Nucfa1oo9606	intact-crc:F89A1E3743154862|rigid:PTA3oZL7c7aWBEoYMxjMcJObqJA	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P28004	uniprotkb:Q5T124-6	intact:EBI-20640|uniprotkb:D6VPI6|ensemblfungi:YAL032C	intact:EBI-11524408	psi-mi:prp45_yeast(display_long)|uniprotkb:YAL032C(locus name)|uniprotkb:PRP45(gene name)|psi-mi:PRP45(display_short)|uniprotkb:FUN20(gene name synonym)	psi-mi:q5t124-6(display_long)|uniprotkb:UBXN11(gene name)|psi-mi:UBXN11(display_short)|uniprotkb:Colorectal tumor-associated antigen COA-1(gene name synonym)|uniprotkb:SOC(gene name synonym)|uniprotkb:Socius(gene name synonym)|uniprotkb:UBX domain-containing protein 5(gene name synonym)|uniprotkb:UBXD5(gene name synonym)|uniprotkb:PP2243(orf name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552020|imex:IM-24995-3576	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009370.1|sgd:S000000030|ensemblfungi:YAL032C(gene)|ensemblfungi:YAL032C_mRNA(transcript)|go:"GO:0000350"(generation of catalytic spliceosome for second transesterification step)|go:"GO:0005634"(nucleus)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|interpro:IPR004015(SKIP/SNW)|interpro:IPR017862|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|dip:DIP-2774N|mint:P28004	intact:EBI-746004(isoform-parent)|uniprotkb:Q5T124-6(isoform-parent)	-	crc64:FE5A724186D7FE84	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:qoHF1UsO3k+JOTOfigSuy2P84/k559292	rogid:1YSjG/p2ihcjl4P8KdPCaX2HxiY9606	intact-crc:2092B56602DAEED9|rigid:LrNsNOcmHu7Nauf8ed4RBHZX+Wg	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
intact:EBI-11523186	uniprotkb:P11747	-	intact:EBI-18897|uniprotkb:D6W0I7|ensemblfungi:YML098W	psi-mi:q5t063_human(display_short)|psi-mi:EBI-11523186(display_long)|uniprotkb:COQ3(gene name)|psi-mi:COQ3(display_short)	psi-mi:taf13_yeast(display_long)|uniprotkb:TAF13(gene name)|psi-mi:TAF13(display_short)|uniprotkb:FUN81(gene name synonym)|uniprotkb:TAF19(gene name synonym)|uniprotkb:YML098W(locus name)|uniprotkb:TBP-associated factor 13(gene name synonym)|uniprotkb:TBP-associated factor 19 kDa(gene name synonym)|uniprotkb:TAFII-19(gene name synonym)|uniprotkb:Function unknown 81 protein(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552016|imex:IM-24995-3575	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:Q5T063(uniprot-removed-ac)	refseq:NP_013611.1|sgd:S000004564|ensemblfungi:YML098W(gene)|ensemblfungi:YML098W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|interpro:IPR003195(Transcription initiation factor IID, 18 kDa subunit)|interpro:IPR009072(Histone-fold)|reactome:R-SCE-674695|reactome:R-SCE-6807505|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-76042|dip:DIP-2054N|mint:P11747	-	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:A5Vp86bBACqUThgdTwfnKnqyE6c9606	rogid:N+MUCqLYlBQa1L2NcpyY5ImMIYM559292	intact-crc:21853002C7626CBA|rigid:8gx9Dw6LjBH5VRxbQobSaSpEuIc	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q5JST6	uniprotkb:P40482	intact:EBI-2349927|uniprotkb:Q9H653|uniprotkb:Q5JST8|uniprotkb:Q68DK4|uniprotkb:Q8NEI0|intact:EBI-28971886|ensembl:ENSP00000404232	intact:EBI-16592|ensemblfungi:YIL109C|uniprotkb:D6VVH8	psi-mi:efhc2_human(display_long)|uniprotkb:EFHC2(gene name)|psi-mi:EFHC2(display_short)	psi-mi:sec24_yeast(display_long)|uniprotkb:SEC24(gene name)|psi-mi:SEC24(display_short)|uniprotkb:Abnormal nuclear morphology 1(gene name synonym)|uniprotkb:ANU1(gene name synonym)|uniprotkb:YIL109C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551984|imex:IM-24995-3567	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000404232|refseq:NP_079460.2|ensembl:ENSG00000183690(gene)|ensembl:ENST00000420999(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005930"(axoneme)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0060285"(cilium-dependent cell motility)|go:"GO:0072686"(mitotic spindle)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR006602(Region of unknown function DM10)|interpro:IPR011992(EF-Hand type)|interpro:IPR040193|rcsb pdb:2Z13|rcsb pdb:2Z14	refseq:NP_012157.3|ensemblfungi:YIL109C(gene)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016236"(macroautophagy)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0070971"(endoplasmic reticulum exit site)|ensemblfungi:YIL109C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0090110"(COPII-coated vesicle cargo loading)|interpro:IPR006895(Zinc finger, Sec23/Sec24-type)|interpro:IPR006896(Sec23/Sec24 trunk region)|interpro:IPR006900(Sec23/Sec24 helical region)|interpro:IPR007123(Gelsolin region)|interpro:IPR012990(Sec23/Sec24 beta-sandwich)|interpro:IPR029006|interpro:IPR036174|interpro:IPR036175|interpro:IPR036180|go:"GO:0000149"(SNARE binding)|go:"GO:0000329"(fungal-type vacuole membrane)|interpro:IPR036465|interpro:IPR041742|rcsb pdb:1M2V|rcsb pdb:1PCX|rcsb pdb:1PD0|rcsb pdb:1PD1|rcsb pdb:4BZI|rcsb pdb:6GNI|rcsb pdb:6ZGA|reactome:R-SCE-204005|reactome:R-SCE-5694530|reactome:R-SCE-983170|go:"GO:0005048"(signal sequence binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|sgd:S000001371|dip:DIP-2233N|mint:P40482	-	-	crc64:35E2BDD24CC75899	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:O1XriQSkLcYkk7H7AlanQ1FKIBY9606	rogid:e7ekVFzZJMZvfRUZ9Q2jDQ/hvs0559292	intact-crc:9E28C71788E54D74|rigid:K+jf9WcEspZ15KZ93IpZr04HG7I	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P38340	uniprotkb:Q5JST6	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-2349927|uniprotkb:Q9H653|uniprotkb:Q5JST8|uniprotkb:Q68DK4|uniprotkb:Q8NEI0|intact:EBI-28971886|ensembl:ENSP00000404232	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:efhc2_human(display_long)|uniprotkb:EFHC2(gene name)|psi-mi:EFHC2(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552004|imex:IM-24995-3572	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F	ensembl:ENSP00000404232|refseq:NP_079460.2|ensembl:ENSG00000183690(gene)|ensembl:ENST00000420999(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005930"(axoneme)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0060285"(cilium-dependent cell motility)|go:"GO:0072686"(mitotic spindle)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR006602(Region of unknown function DM10)|interpro:IPR011992(EF-Hand type)|interpro:IPR040193|rcsb pdb:2Z13|rcsb pdb:2Z14	-	crc64:66699F37B0013088	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:O1XriQSkLcYkk7H7AlanQ1FKIBY9606	intact-crc:E6FCC244DF9B9246|rigid:sbi4qDEg3OEUgfzrgQnqO7aHA24	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q5SW96	uniprotkb:P38263	intact:EBI-747813|uniprotkb:A2BHI5|uniprotkb:Q6TQS9|uniprotkb:Q8N2Y0|uniprotkb:Q9UFI9|intact:EBI-28971912|ensembl:ENSP00000363458	intact:EBI-20304|uniprotkb:D6VQA4|ensemblfungi:YBR105C	psi-mi:arh_human(display_long)|uniprotkb:Autosomal recessive hypercholesterolemia protein(gene name synonym)|uniprotkb:LDLRAP1(gene name)|psi-mi:LDLRAP1(display_short)|uniprotkb:ARH(gene name synonym)	psi-mi:gid4_yeast(display_long)|uniprotkb:VID24(gene name)|psi-mi:VID24(display_short)|uniprotkb:YBR105C(locus name)|uniprotkb:YBR0834(orf name)|uniprotkb:GID4(gene name synonym)|uniprotkb:Glucose-induced degradation protein 4(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552012|imex:IM-24995-3574	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000363458|refseq:NP_056442.2|go:"GO:0042982"(amyloid precursor protein metabolic process)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0055037"(recycling endosome)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0090118"(receptor-mediated endocytosis involved in cholesterol transport)|go:"GO:0090205"(positive regulation of cholesterol metabolic process)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905581"(positive regulation of low-density lipoprotein particle clearance)|go:"GO:1905602"(positive regulation of receptor-mediated endocytosis involved in cholesterol transport)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|rcsb pdb:2G30|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8964026|reactome:R-HSA-8964038|ensembl:ENSG00000157978(gene)|ensembl:ENST00000374338(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005883"(neurofilament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030276"(clathrin binding)|go:"GO:0030301"(cholesterol transport)|go:"GO:0030424"(axon)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031623"(receptor internalization)|go:"GO:0034383"(low-density lipoprotein particle clearance)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0035612"(AP-2 adaptor complex binding)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0035650"(AP-1 adaptor complex binding)|go:"GO:0042632"(cholesterol homeostasis)	refseq:NP_009663.1|sgd:S000000309|ensemblfungi:YBR105C(gene)|ensemblfungi:YBR105C_mRNA(transcript)|go:"GO:0005773"(vacuole)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0007039"(protein catabolic process in the vacuole)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034657"(GID complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045721"(negative regulation of gluconeogenesis)|go:"GO:0071596"(ubiquitin-dependent protein catabolic process via the N-end rule pathway)|interpro:IPR018618|rcsb pdb:6SWY|dip:DIP-4502N|mint:P38263	-	-	crc64:FF020B239676E0B2	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:dtBWLcVpVD/R0aKQZr9Nucfa1oo9606	rogid:ag6caXMIP/qIv27yJtSEmlBoI7g559292	intact-crc:B83A75EA46634ED5|rigid:fXQk8T6iq+9VLa3t8eummQvUx0o	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P53038	uniprotkb:Q5JST6	intact:EBI-19106|uniprotkb:D6VUN1|ensemblfungi:YGR099W	intact:EBI-2349927|uniprotkb:Q9H653|uniprotkb:Q5JST8|uniprotkb:Q68DK4|uniprotkb:Q8NEI0|intact:EBI-28971886|ensembl:ENSP00000404232	psi-mi:tel2_yeast(display_long)|uniprotkb:YGR099W(locus name)|uniprotkb:TEL2(gene name)|psi-mi:TEL2(display_short)	psi-mi:efhc2_human(display_long)|uniprotkb:EFHC2(gene name)|psi-mi:EFHC2(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551992|imex:IM-24995-3569	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003331|ensemblfungi:YGR099W(gene)|ensemblfungi:YGR099W_mRNA(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0005829"(cytosol)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0034502"(protein localization to chromosome)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0070209"(ASTRA complex)|interpro:IPR019337|interpro:IPR038528|rcsb pdb:3O4Z|refseq:NP_011613.3|dip:DIP-1245N|mint:P53038	ensembl:ENSP00000404232|refseq:NP_079460.2|ensembl:ENSG00000183690(gene)|ensembl:ENST00000420999(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005930"(axoneme)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0060285"(cilium-dependent cell motility)|go:"GO:0072686"(mitotic spindle)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR006602(Region of unknown function DM10)|interpro:IPR011992(EF-Hand type)|interpro:IPR040193|rcsb pdb:2Z13|rcsb pdb:2Z14	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:SZibPBili0M8YgHIwxf+sKkLk+M559292	rogid:O1XriQSkLcYkk7H7AlanQ1FKIBY9606	intact-crc:470AC07F01D5D6AC|rigid:9giCatqt8PuQndlqWKpR+671cbI	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P26448	uniprotkb:Q5JST6	intact:EBI-3824|uniprotkb:D6VZN0|ensemblfungi:YMR055C	intact:EBI-2349927|uniprotkb:Q9H653|uniprotkb:Q5JST8|uniprotkb:Q68DK4|uniprotkb:Q8NEI0|intact:EBI-28971886|ensembl:ENSP00000404232	psi-mi:bub2_yeast(display_long)|uniprotkb:BUB2(gene name)|psi-mi:BUB2(display_short)|uniprotkb:YMR055C(locus name)|uniprotkb:YM9796.08C(orf name)|uniprotkb:Cell cycle arrest protein BUB2(gene name synonym)	psi-mi:efhc2_human(display_long)|uniprotkb:EFHC2(gene name)|psi-mi:EFHC2(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551996|imex:IM-24995-3570	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013771.1|sgd:S000004659|dip:DIP-1215N|mint:P26448|ensemblfungi:YMR055C(gene)|ensemblfungi:YMR055C_mRNA(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0031030"(negative regulation of septation initiation signaling)|go:"GO:0031578"(mitotic spindle orientation checkpoint signaling)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0051301"(cell division)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:1902543"(negative regulation of protein localization to mitotic spindle pole body)|go:"GO:1990334"(Bfa1-Bub2 complex)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR035969	ensembl:ENSP00000404232|refseq:NP_079460.2|ensembl:ENSG00000183690(gene)|ensembl:ENST00000420999(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005930"(axoneme)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0060285"(cilium-dependent cell motility)|go:"GO:0072686"(mitotic spindle)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR006602(Region of unknown function DM10)|interpro:IPR011992(EF-Hand type)|interpro:IPR040193|rcsb pdb:2Z13|rcsb pdb:2Z14	-	crc64:A1DDBFB548E81EA3	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:+03m4HOOcKjpSjqpEZ8wCgD2Egc559292	rogid:O1XriQSkLcYkk7H7AlanQ1FKIBY9606	intact-crc:9C99A9F221571996|rigid:zdhzFGfHhDSLfJrIv4Q+DERAIGw	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q03759	uniprotkb:Q5JST6	intact:EBI-27937|uniprotkb:D6W0H6|ensemblfungi:YML108W	intact:EBI-2349927|uniprotkb:Q9H653|uniprotkb:Q5JST8|uniprotkb:Q68DK4|uniprotkb:Q8NEI0|intact:EBI-28971886|ensembl:ENSP00000404232	psi-mi:ymk8_yeast(display_long)|uniprotkb:YM8339.11(orf name)|uniprotkb:YML108W(locus name)	psi-mi:efhc2_human(display_long)|uniprotkb:EFHC2(gene name)|psi-mi:EFHC2(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552000|imex:IM-24995-3571	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013599.1|sgd:S000004576|dip:DIP-3849N|ensemblfungi:YML108W(gene)|ensemblfungi:YML108W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|interpro:IPR015080(Protein of unknown function DUF1892)|interpro:IPR035946|rcsb pdb:1N6Z	ensembl:ENSP00000404232|refseq:NP_079460.2|ensembl:ENSG00000183690(gene)|ensembl:ENST00000420999(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005930"(axoneme)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0060285"(cilium-dependent cell motility)|go:"GO:0072686"(mitotic spindle)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR006602(Region of unknown function DM10)|interpro:IPR011992(EF-Hand type)|interpro:IPR040193|rcsb pdb:2Z13|rcsb pdb:2Z14	-	crc64:8D07986085C369C4	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:SLeZv2kwwNuEtzk4nFkrHoP4HOo559292	rogid:O1XriQSkLcYkk7H7AlanQ1FKIBY9606	intact-crc:93EC7B326EE5856F|rigid:5cqc0lY4K7kuTXTQS+ghLIml7NU	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q5JST6	uniprotkb:Q04087	intact:EBI-2349927|uniprotkb:Q9H653|uniprotkb:Q5JST8|uniprotkb:Q68DK4|uniprotkb:Q8NEI0|intact:EBI-28971886|ensembl:ENSP00000404232	intact:EBI-32189|uniprotkb:D6VT66|ensemblfungi:YDR439W	psi-mi:efhc2_human(display_long)|uniprotkb:EFHC2(gene name)|psi-mi:EFHC2(display_short)	psi-mi:lrs4_yeast(display_long)|uniprotkb:Loss of rDNA silencing protein 4(gene name synonym)|uniprotkb:LRS4(gene name)|psi-mi:LRS4(display_short)|uniprotkb:D9461.25(orf name)|uniprotkb:YDR439W(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11551988|imex:IM-24995-3568	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000404232|refseq:NP_079460.2|ensembl:ENSG00000183690(gene)|ensembl:ENST00000420999(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005930"(axoneme)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0060285"(cilium-dependent cell motility)|go:"GO:0072686"(mitotic spindle)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR006602(Region of unknown function DM10)|interpro:IPR011992(EF-Hand type)|interpro:IPR040193|rcsb pdb:2Z13|rcsb pdb:2Z14	refseq:NP_010727.1|sgd:S000002847|dip:DIP-1416N|mint:Q04087|ensemblfungi:YDR439W(gene)|ensemblfungi:YDR439W_mRNA(transcript)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0033551"(monopolin complex)|go:"GO:0034503"(protein localization to nucleolar rDNA repeats)|go:"GO:0045143"(homologous chromosome segregation)|go:"GO:0051455"(monopolar spindle attachment to meiosis I kinetochore)|go:"GO:0070550"(rDNA condensation)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|interpro:IPR018479|rcsb pdb:3N7N	-	-	crc64:60D880BA947B9005	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:O1XriQSkLcYkk7H7AlanQ1FKIBY9606	rogid:XJ/t2ftZBXOTJshr/zQeMxci/6Q559292	intact-crc:D1B1E7EC6BFE086C|rigid:G9MVygKpQUyOlAlbHk3FtZJ1nVc	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q5VSY0	uniprotkb:P32502	intact:EBI-743722|uniprotkb:Q9BYI2|uniprotkb:Q96LI0|uniprotkb:Q9BYI1|uniprotkb:Q9H225|ensembl:ENSP00000365550	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:gkap1_human(display_long)|uniprotkb:GKAP42(gene name synonym)|uniprotkb:cGMP-dependent protein kinase-anchoring protein of 42 kDa(gene name synonym)|uniprotkb:FKSG21(orf name)|uniprotkb:GKAP1(gene name)|psi-mi:GKAP1(display_short)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552064|imex:IM-24995-3587	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000165113(gene)|refseq:NP_001129425.1|refseq:NP_079487.2|refseq:XP_011517360.1|refseq:XP_005252298.1|ensembl:ENST00000376371(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0007165"(signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|interpro:IPR026109|dip:DIP-47324N	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731	-	-	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:WPAqDDTftv300tbwXkusTo6tmUo9606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:D0CDE17C9B90A1EA|rigid:CoAQLd/ljLQV7hG1azX99tfKnaI	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q5VSY0	uniprotkb:Q12161	intact:EBI-743722|uniprotkb:Q9BYI2|uniprotkb:Q96LI0|uniprotkb:Q9BYI1|uniprotkb:Q9H225|ensembl:ENSP00000365550	intact:EBI-34372|uniprotkb:D6W213|ensemblfungi:YOL054W	psi-mi:gkap1_human(display_long)|uniprotkb:GKAP42(gene name synonym)|uniprotkb:cGMP-dependent protein kinase-anchoring protein of 42 kDa(gene name synonym)|uniprotkb:FKSG21(orf name)|uniprotkb:GKAP1(gene name)|psi-mi:GKAP1(display_short)	psi-mi:psh1_yeast(display_long)|uniprotkb:PSH1(gene name)|psi-mi:PSH1(display_short)|uniprotkb:POB3/SPT16 histone-associated protein 1(gene name synonym)|uniprotkb:O1263(orf name)|uniprotkb:YOL054W(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552060|imex:IM-24995-3586	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000165113(gene)|refseq:NP_001129425.1|refseq:NP_079487.2|refseq:XP_011517360.1|refseq:XP_005252298.1|ensembl:ENST00000376371(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0007165"(signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|interpro:IPR026109|dip:DIP-47324N	refseq:NP_014587.1|sgd:S000005415|mint:Q12161|dip:DIP-6481N|ensemblfungi:YOL054W(gene)|ensemblfungi:YOL054W_mRNA(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907	-	-	crc64:CE0ECBCB6D465554	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:WPAqDDTftv300tbwXkusTo6tmUo9606	rogid:AvPMRd/GjfaTyQjEfMPhBVcvOs4559292	intact-crc:E6D0D3D7D2291DBC|rigid:zR49SS5SPC1KEyxWuv82qic6mjc	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
intact:EBI-11522444	uniprotkb:Q5TD97	-	intact:EBI-750641|uniprotkb:Q5TD98|uniprotkb:Q8WW21|uniprotkb:Q9NQU2|uniprotkb:B2RBD1|uniprotkb:E1P526|ensembl:ENSP00000326022|ensembl:ENSP00000396390|ensembl:ENSP00000442357	psi-mi:sen15(display_short)|psi-mi:EBI-11522444(display_long)	psi-mi:fhl5_human(display_long)|uniprotkb:Activator of cAMP-responsive element modulator in testis(gene name synonym)|uniprotkb:FHL5(gene name)|psi-mi:FHL5(display_short)|uniprotkb:ACT(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552056|imex:IM-24995-3585	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001164278.1|refseq:NP_065228.4|refseq:NP_001309395.1|refseq:NP_001309396.1|ensembl:ENSG00000112214(gene)|ensembl:ENST00000326771(transcript)|ensembl:ENST00000450218(transcript)|ensembl:ENST00000541107(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0030018"(Z disc)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR037987|interpro:IPR042947|mint:Q5TD97|rcsb pdb:1X68	-	no-uniprot-update:	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:mmn7/rD7T68r+kJ8RV9USn4gnNI4932	rogid:AYHIHh+ibS4sNYAZY4ghojZOJOI9606	intact-crc:D70BC7DD67251178|rigid:4Hg+guIIlsN0d0amItLmu80gYKc	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P53286	uniprotkb:Q5T124-6	intact:EBI-3796|uniprotkb:D6VUS2|ensemblfungi:YGR142W	intact:EBI-11524408	psi-mi:btn2_yeast(display_long)|uniprotkb:YGR142W(locus name)|uniprotkb:BTN2(gene name)|psi-mi:BTN2(display_short)|uniprotkb:Batten disease protein 2(gene name synonym)	psi-mi:q5t124-6(display_long)|uniprotkb:UBXN11(gene name)|psi-mi:UBXN11(display_short)|uniprotkb:Colorectal tumor-associated antigen COA-1(gene name synonym)|uniprotkb:SOC(gene name synonym)|uniprotkb:Socius(gene name synonym)|uniprotkb:UBX domain-containing protein 5(gene name synonym)|uniprotkb:UBXD5(gene name synonym)|uniprotkb:PP2243(orf name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552052|imex:IM-24995-3584	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003374|refseq:NP_011658.3|dip:DIP-5534N|mint:P53286|ensemblfungi:YGR142W(gene)|ensemblfungi:YGR142W_mRNA(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005634"(nucleus)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006865"(amino acid transport)|go:"GO:0006885"(regulation of pH)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051087"(chaperone binding)|go:"GO:0140311"(protein sequestering activity)	intact:EBI-746004(isoform-parent)|uniprotkb:Q5T124-6(isoform-parent)	-	crc64:E7AE1EB1E3612F3E	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Cu27xkwGMNyS4zLvUaG1UeH2mE0559292	rogid:1YSjG/p2ihcjl4P8KdPCaX2HxiY9606	intact-crc:3056EA601F2B03F9|rigid:ja8+IzdWLG0ECQqfwNmkJEO2qik	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P32902	uniprotkb:Q5T124-6	intact:EBI-16248|ensemblfungi:YHL004W|uniprotkb:D3DKR0	intact:EBI-11524408	psi-mi:rt04_yeast(display_long)|uniprotkb:MRP4(gene name)|psi-mi:MRP4(display_short)|uniprotkb:MRP4A(gene name synonym)|uniprotkb:Mitochondrial small ribosomal subunit protein uS2m(gene name synonym)|uniprotkb:YHL004W(locus name)	psi-mi:q5t124-6(display_long)|uniprotkb:UBXN11(gene name)|psi-mi:UBXN11(display_short)|uniprotkb:Colorectal tumor-associated antigen COA-1(gene name synonym)|uniprotkb:SOC(gene name synonym)|uniprotkb:Socius(gene name synonym)|uniprotkb:UBX domain-containing protein 5(gene name synonym)|uniprotkb:UBXD5(gene name synonym)|uniprotkb:PP2243(orf name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552048|imex:IM-24995-3583	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YHL004W(gene)|ensemblfungi:YHL004W_mRNA(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR001865(Ribosomal protein S2)|interpro:IPR005706(Ribosomal protein S2, bacterial-type)|interpro:IPR018130|interpro:IPR023591|rcsb pdb:5MRC|rcsb pdb:5MRE|rcsb pdb:5MRF|refseq:NP_011859.1|sgd:S000000996|dip:DIP-5035N|mint:P32902	intact:EBI-746004(isoform-parent)|uniprotkb:Q5T124-6(isoform-parent)	-	crc64:81A1CB33134BC559	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:BlL3W6HUN+uAKF/AxwlV1zT5YZQ559292	rogid:1YSjG/p2ihcjl4P8KdPCaX2HxiY9606	intact-crc:C63E1C44406DD855|rigid:Rn3lxpxa/3W/L2hcoFjM/QSt1G4	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q12329	uniprotkb:Q5T124-6	intact:EBI-8571|uniprotkb:D6VSF3|ensemblfungi:YDR171W	intact:EBI-11524408	psi-mi:hsp42_yeast(display_long)|uniprotkb:HSP42(gene name)|psi-mi:HSP42(display_short)|uniprotkb:YDR171W(locus name)|uniprotkb:YD9395.04(orf name)|uniprotkb:42 kDa heat shock protein(gene name synonym)	psi-mi:q5t124-6(display_long)|uniprotkb:UBXN11(gene name)|psi-mi:UBXN11(display_short)|uniprotkb:Colorectal tumor-associated antigen COA-1(gene name synonym)|uniprotkb:SOC(gene name synonym)|uniprotkb:Socius(gene name synonym)|uniprotkb:UBX domain-containing protein 5(gene name synonym)|uniprotkb:UBXD5(gene name synonym)|uniprotkb:PP2243(orf name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552040|imex:IM-24995-3581	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010456.1|sgd:S000002578|mint:Q12329|dip:DIP-2515N|ensemblfungi:YDR171W(gene)|ensemblfungi:YDR171W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0009408"(response to heat)|go:"GO:0009651"(response to salt stress)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043621"(protein self-association)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0140311"(protein sequestering activity)|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR031107	intact:EBI-746004(isoform-parent)|uniprotkb:Q5T124-6(isoform-parent)	-	crc64:DF353A76493E3CE6	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:izvrv04fA3zcBqTeUeHD/erKGf4559292	rogid:1YSjG/p2ihcjl4P8KdPCaX2HxiY9606	intact-crc:EF02D8F23768C50F|rigid:6C7uPE50u2e0rlNYgtHYRIEau/I	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P52917	uniprotkb:Q5T124-6	intact:EBI-20475|uniprotkb:D6W4H4|ensemblfungi:YPR173C	intact:EBI-11524408	psi-mi:vps4_yeast(display_long)|uniprotkb:VPS4(gene name)|psi-mi:VPS4(display_short)|uniprotkb:CSC1(gene name synonym)|uniprotkb:END13(gene name synonym)|uniprotkb:GRD13(gene name synonym)|uniprotkb:DID6(gene name synonym)|uniprotkb:Protein END13(gene name synonym)|uniprotkb:DOA4-independent degradation protein 6(gene name synonym)|uniprotkb:Vacuolar protein-targeting protein 10(gene name synonym)|uniprotkb:VPL4(gene name synonym)|uniprotkb:VPT10(gene name synonym)|uniprotkb:P9705.10(orf name)|uniprotkb:YPR173C(locus name)	psi-mi:q5t124-6(display_long)|uniprotkb:UBXN11(gene name)|psi-mi:UBXN11(display_short)|uniprotkb:Colorectal tumor-associated antigen COA-1(gene name synonym)|uniprotkb:SOC(gene name synonym)|uniprotkb:Socius(gene name synonym)|uniprotkb:UBX domain-containing protein 5(gene name synonym)|uniprotkb:UBXD5(gene name synonym)|uniprotkb:PP2243(orf name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552036|imex:IM-24995-3580	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015499.1|sgd:S000006377|ensemblfungi:YPR173C(gene)|ensemblfungi:YPR173C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0007033"(vacuole organization)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0016197"(endosomal transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045053"(protein retention in Golgi apparatus)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0061709"(reticulophagy)|go:"GO:0070676"(intralumenal vesicle formation)|go:"GO:1990621"(ESCRT IV complex)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR007330(MIT)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR027417|interpro:IPR036181|rcsb pdb:2QP9|rcsb pdb:2QPA|rcsb pdb:2RKO|rcsb pdb:2V6X|rcsb pdb:3EIE|rcsb pdb:3EIH|rcsb pdb:3MHV|rcsb pdb:4NIQ|rcsb pdb:5FVK|rcsb pdb:5FVL|rcsb pdb:5UIE|rcsb pdb:5XMI|rcsb pdb:5XMK|rcsb pdb:6AP1|rcsb pdb:6BMF|rcsb pdb:6NDY|rcsb pdb:6OO2|reactome:R-SCE-917729|reactome:R-SCE-9668328|dip:DIP-1746N|mint:P52917	intact:EBI-746004(isoform-parent)|uniprotkb:Q5T124-6(isoform-parent)	-	crc64:E65BCDB19C9510DD	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:qXGTfZcBZ9jWOVjm6tl3wIR/ngM559292	rogid:1YSjG/p2ihcjl4P8KdPCaX2HxiY9606	intact-crc:E3668B249CF8647F|rigid:7O1nNDYAqyasMOpQILRuAfgc7y0	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q5T124-6	uniprotkb:P32502	intact:EBI-11524408	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:q5t124-6(display_long)|uniprotkb:UBXN11(gene name)|psi-mi:UBXN11(display_short)|uniprotkb:Colorectal tumor-associated antigen COA-1(gene name synonym)|uniprotkb:SOC(gene name synonym)|uniprotkb:Socius(gene name synonym)|uniprotkb:UBX domain-containing protein 5(gene name synonym)|uniprotkb:UBXD5(gene name synonym)|uniprotkb:PP2243(orf name)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552032|imex:IM-24995-3579	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-746004(isoform-parent)|uniprotkb:Q5T124-6(isoform-parent)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731	-	-	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:1YSjG/p2ihcjl4P8KdPCaX2HxiY9606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:3A93B6D7D195E327|rigid:TCELETJrv2CLPOCOuIEVqKThbSA	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P40482	uniprotkb:Q5T124-6	intact:EBI-16592|ensemblfungi:YIL109C|uniprotkb:D6VVH8	intact:EBI-11524408	psi-mi:sec24_yeast(display_long)|uniprotkb:SEC24(gene name)|psi-mi:SEC24(display_short)|uniprotkb:Abnormal nuclear morphology 1(gene name synonym)|uniprotkb:ANU1(gene name synonym)|uniprotkb:YIL109C(locus name)	psi-mi:q5t124-6(display_long)|uniprotkb:UBXN11(gene name)|psi-mi:UBXN11(display_short)|uniprotkb:Colorectal tumor-associated antigen COA-1(gene name synonym)|uniprotkb:SOC(gene name synonym)|uniprotkb:Socius(gene name synonym)|uniprotkb:UBX domain-containing protein 5(gene name synonym)|uniprotkb:UBXD5(gene name synonym)|uniprotkb:PP2243(orf name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552028|imex:IM-24995-3578	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012157.3|ensemblfungi:YIL109C(gene)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016236"(macroautophagy)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0070971"(endoplasmic reticulum exit site)|ensemblfungi:YIL109C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0090110"(COPII-coated vesicle cargo loading)|interpro:IPR006895(Zinc finger, Sec23/Sec24-type)|interpro:IPR006896(Sec23/Sec24 trunk region)|interpro:IPR006900(Sec23/Sec24 helical region)|interpro:IPR007123(Gelsolin region)|interpro:IPR012990(Sec23/Sec24 beta-sandwich)|interpro:IPR029006|interpro:IPR036174|interpro:IPR036175|interpro:IPR036180|go:"GO:0000149"(SNARE binding)|go:"GO:0000329"(fungal-type vacuole membrane)|interpro:IPR036465|interpro:IPR041742|rcsb pdb:1M2V|rcsb pdb:1PCX|rcsb pdb:1PD0|rcsb pdb:1PD1|rcsb pdb:4BZI|rcsb pdb:6GNI|rcsb pdb:6ZGA|reactome:R-SCE-204005|reactome:R-SCE-5694530|reactome:R-SCE-983170|go:"GO:0005048"(signal sequence binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|sgd:S000001371|dip:DIP-2233N|mint:P40482	intact:EBI-746004(isoform-parent)|uniprotkb:Q5T124-6(isoform-parent)	-	crc64:35E2BDD24CC75899	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:e7ekVFzZJMZvfRUZ9Q2jDQ/hvs0559292	rogid:1YSjG/p2ihcjl4P8KdPCaX2HxiY9606	intact-crc:FAD5CE2B03E2A047|rigid:9dTYfYSi8mp0xvSI86f7WG71xgw	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P38340	uniprotkb:Q5T124-6	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-11524408	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:q5t124-6(display_long)|uniprotkb:UBXN11(gene name)|psi-mi:UBXN11(display_short)|uniprotkb:Colorectal tumor-associated antigen COA-1(gene name synonym)|uniprotkb:SOC(gene name synonym)|uniprotkb:Socius(gene name synonym)|uniprotkb:UBX domain-containing protein 5(gene name synonym)|uniprotkb:UBXD5(gene name synonym)|uniprotkb:PP2243(orf name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552024|imex:IM-24995-3577	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F	intact:EBI-746004(isoform-parent)|uniprotkb:Q5T124-6(isoform-parent)	-	crc64:66699F37B0013088	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:1YSjG/p2ihcjl4P8KdPCaX2HxiY9606	intact-crc:8F60DDBFD486B118|rigid:mJIZimAvyqKNqPRmPVlcNf+vq5E	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P25372	uniprotkb:Q5T124-6	intact:EBI-19616|uniprotkb:D6VR84|ensemblfungi:YCR083W	intact:EBI-11524408	psi-mi:trx3_yeast(display_long)|uniprotkb:TRX3(gene name)|psi-mi:TRX3(display_short)|uniprotkb:YCR83W(orf name)|uniprotkb:YCR083W(locus name)	psi-mi:q5t124-6(display_long)|uniprotkb:UBXN11(gene name)|psi-mi:UBXN11(display_short)|uniprotkb:Colorectal tumor-associated antigen COA-1(gene name synonym)|uniprotkb:SOC(gene name synonym)|uniprotkb:Socius(gene name synonym)|uniprotkb:UBX domain-containing protein 5(gene name synonym)|uniprotkb:UBXD5(gene name synonym)|uniprotkb:PP2243(orf name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552044|imex:IM-24995-3582	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR036249|refseq:NP_010006.1|sgd:S000000679|interpro:IPR017937|interpro:IPR013766(Thioredoxin domain)|rcsb pdb:2OE0|rcsb pdb:2OE1|rcsb pdb:2OE3|ensemblfungi:YCR083W(gene)|ensemblfungi:YCR083W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0015036"(disulfide oxidoreductase activity)|go:"GO:0034599"(cellular response to oxidative stress)|rcsb pdb:5YKW	intact:EBI-746004(isoform-parent)|uniprotkb:Q5T124-6(isoform-parent)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:g0xjGf9GvJRl8iv2qoT5tOs7jXI559292	rogid:1YSjG/p2ihcjl4P8KdPCaX2HxiY9606	intact-crc:30DECFAD3461E68D|rigid:u+mMQM8pDMXQxLofCI551fVRpVk	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P40956	uniprotkb:Q6P1W5	intact:EBI-7968|uniprotkb:D6VTX2|ensemblfungi:YGL181W	intact:EBI-946029|uniprotkb:B3KVT1|uniprotkb:Q96IC8|ensembl:ENSP00000435634|uniprotkb:D3DPR3|uniprotkb:E9PJ76	psi-mi:gts1_yeast(display_long)|uniprotkb:YGL181W(locus name)|uniprotkb:GTS1(gene name)|psi-mi:GTS1(display_short)|uniprotkb:LSR1(gene name synonym)|uniprotkb:Protein LSR1(gene name synonym)	psi-mi:ca094_human(display_long)|uniprotkb:C1orf94(gene name)|psi-mi:C1orf94(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552100|imex:IM-24995-3596	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011334.1|sgd:S000003149|mint:P40956|dip:DIP-2746N|ensemblfungi:YGL181W(gene)|ensemblfungi:YGL181W_mRNA(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0006897"(endocytosis)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010512"(negative regulation of phosphatidylinositol biosynthetic process)|go:"GO:0030479"(actin cortical patch)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR037278|interpro:IPR038508	refseq:NP_001128206.1|refseq:NP_116273.2|ensembl:ENSG00000142698(gene)|ensembl:ENST00000488417(transcript)|interpro:IPR031496	-	crc64:D687E3BF6B620795	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:8kgpssCRrHiTHsFaOH2nDK6EIjk559292	rogid:y1o4xWvTl2CBA1J7jsP7y8ZjLzM9606	intact-crc:142956A0DD190F74|rigid:2rsxj/TugFNarklH///ujv8mEKg	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q6P1W5	uniprotkb:P53919	intact:EBI-946029|uniprotkb:B3KVT1|uniprotkb:Q96IC8|ensembl:ENSP00000435634|uniprotkb:D3DPR3|uniprotkb:E9PJ76	intact:EBI-28887|uniprotkb:B0KZR2|uniprotkb:B0KZS1|uniprotkb:B0KZT9|uniprotkb:B0KZZ3|uniprotkb:B0L002|uniprotkb:D6W159|ensemblfungi:YNL124W	psi-mi:ca094_human(display_long)|uniprotkb:C1orf94(gene name)|psi-mi:C1orf94(display_short)	psi-mi:naf1_yeast(display_long)|uniprotkb:YNL124W(locus name)|uniprotkb:N1888(orf name)|uniprotkb:NAF1(gene name)|psi-mi:NAF1(display_short)|uniprotkb:Nuclear assembly factor 1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552096|imex:IM-24995-3595	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001128206.1|refseq:NP_116273.2|ensembl:ENSG00000142698(gene)|ensembl:ENST00000488417(transcript)|interpro:IPR031496	sgd:S000005068|refseq:NP_014275.3|dip:DIP-4345N|ensemblfungi:YNL124W(gene)|ensemblfungi:YNL124W_mRNA(transcript)|go:"GO:0000493"(box H/ACA snoRNP assembly)|go:"GO:0001522"(pseudouridine synthesis)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005732"("sno(s)RNA-containing ribonucleoprotein complex")|go:"GO:0006364"(rRNA processing)|go:"GO:0042254"(ribosome biogenesis)|interpro:IPR007504(Gar1 protein RNA-binding region)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR038664|interpro:IPR040309|rcsb pdb:2V3M	-	-	crc64:5A496278070F6255	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:y1o4xWvTl2CBA1J7jsP7y8ZjLzM9606	rogid:9ZtegpRDLFL25BUqw4ke9qJ393Q559292	intact-crc:802113EB9DFC4E70|rigid:OrHkMbBJnu8C5r+nNaJaggvPGMs	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q6P1W5	uniprotkb:P40473	intact:EBI-946029|uniprotkb:B3KVT1|uniprotkb:Q96IC8|ensembl:ENSP00000435634|uniprotkb:D3DPR3|uniprotkb:E9PJ76	intact:EBI-25207|uniprotkb:D6VVG5|ensemblfungi:YIL122W	psi-mi:ca094_human(display_long)|uniprotkb:C1orf94(gene name)|psi-mi:C1orf94(display_short)	psi-mi:pog1_yeast(display_long)|uniprotkb:YIL122W(locus name)|uniprotkb:POG1(gene name)|psi-mi:POG1(display_short)|uniprotkb:Promoter of growth protein 1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552092|imex:IM-24995-3594	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001128206.1|refseq:NP_116273.2|ensembl:ENSG00000142698(gene)|ensembl:ENST00000488417(transcript)|interpro:IPR031496	sgd:S000001384|refseq:NP_012144.1|dip:DIP-2755N|ensemblfungi:YIL122W(gene)|ensemblfungi:YIL122W_mRNA(transcript)|go:"GO:0000321"(re-entry into mitotic cell cycle after pheromone arrest)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051301"(cell division)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:y1o4xWvTl2CBA1J7jsP7y8ZjLzM9606	rogid:SL7E0QbXBSeu+JDSQhp7p5rNb8M559292	intact-crc:A01DDEE86C300B1C|rigid:sNt+ZNXzPZW48djk2nYkVKMe1kc	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P53286	uniprotkb:Q6IBW4	intact:EBI-3796|uniprotkb:D6VUS2|ensemblfungi:YGR142W	intact:EBI-2548296|ensembl:ENSP00000410088|uniprotkb:Q9BUT3|uniprotkb:Q9BVD1|uniprotkb:B7WPH1|uniprotkb:O43788|uniprotkb:Q13391|uniprotkb:Q96C14|uniprotkb:Q96GJ0|uniprotkb:Q9BQ71	psi-mi:btn2_yeast(display_long)|uniprotkb:YGR142W(locus name)|uniprotkb:BTN2(gene name)|psi-mi:BTN2(display_short)|uniprotkb:Batten disease protein 2(gene name synonym)	psi-mi:cndh2_human(display_long)|uniprotkb:NCAPH2(gene name)|psi-mi:NCAPH2(display_short)|uniprotkb:CAPH2(gene name synonym)|uniprotkb:Non-SMC condensin II complex subunit H2(gene name synonym)|uniprotkb:Chromosome-associated protein H2(gene name synonym)|uniprotkb:Kleisin-beta(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552088|imex:IM-24995-3593	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003374|refseq:NP_011658.3|dip:DIP-5534N|mint:P53286|ensemblfungi:YGR142W(gene)|ensemblfungi:YGR142W_mRNA(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005634"(nucleus)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006865"(amino acid transport)|go:"GO:0006885"(regulation of pH)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051087"(chaperone binding)|go:"GO:0140311"(protein sequestering activity)	ensembl:ENSG00000025770(gene)|ensembl:ENST00000420993(transcript)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000796"(condensin complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0010032"(meiotic chromosome condensation)|go:"GO:0016020"(membrane)|go:"GO:0030054"(cell junction)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0045171"(intercellular bridge)|go:"GO:0051306"(mitotic sister chromatid separation)|go:"GO:0051309"(female meiosis chromosome separation)|interpro:IPR009378(Protein of unknown function DUF1032)|interpro:IPR031719|interpro:IPR031737|interpro:IPR031739|mint:Q6IBW4|reactome:R-HSA-2299718|refseq:NP_001171940.1|refseq:NP_055366.3|refseq:NP_689512.2|dip:DIP-43901N	-	crc64:E7AE1EB1E3612F3E	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Cu27xkwGMNyS4zLvUaG1UeH2mE0559292	rogid:GTOZg0OoAHm+tj3C8/3sCGM+G5E9606	intact-crc:44E96DA90F6234B7|rigid:8Lov5MtCZxiAfmGnN71zLKWgNAk	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q5VWN6	uniprotkb:P89105	intact:EBI-745958|uniprotkb:Q2YD91|uniprotkb:Q5VWN5|uniprotkb:Q6ZRQ8|uniprotkb:Q8IVG4|uniprotkb:Q9BUZ7|uniprotkb:Q9H5J9|uniprotkb:Q9H7A4|uniprotkb:Q9H996|uniprotkb:Q9NXA1|intact:EBI-28974916|ensembl:ENSP00000328426	intact:EBI-5283|uniprotkb:O14409|uniprotkb:Q07332|uniprotkb:Q08292|uniprotkb:D6W1S4|ensemblfungi:YOL145C	psi-mi:taso2_human(display_long)|uniprotkb:TASOR2(gene name)|psi-mi:TASOR2(display_short)|uniprotkb:C10orf18(gene name synonym)|uniprotkb:FAM208B(gene name synonym)|uniprotkb:KIAA2006(gene name synonym)	psi-mi:ctr9_yeast(display_long)|uniprotkb:CTR9(gene name)|psi-mi:CTR9(display_short)|uniprotkb:CDP1(gene name synonym)|uniprotkb:Cln three-requiring protein 9(gene name synonym)|uniprotkb:Centromere-binding factor 1-dependent protein 1(gene name synonym)|uniprotkb:YOL145C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552068|imex:IM-24995-3588	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060252.4|ensembl:ENSP00000328426|refseq:XP_011517827.1|refseq:XP_016871852.1|refseq:XP_016871854.1|ensembl:ENSG00000108021(gene)|ensembl:ENST00000328090(transcript)|go:"GO:0005829"(cytosol)|interpro:IPR022168|interpro:IPR022188|mint:Q5VWN6|go:"GO:0005654"(nucleoplasm)|refseq:XP_005252532.1|refseq:XP_005252537.1|refseq:XP_005252538.1|refseq:XP_005252539.1|refseq:NP_001308712.1|refseq:NP_001308713.1|refseq:NP_001308714.1	refseq:NP_014496.2|sgd:S000005505|dip:DIP-2814N|mint:P89105|ensemblfungi:YOL145C(gene)|ensemblfungi:YOL145C_mRNA(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001015"(snoRNA transcription by RNA polymerase II)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006362"(transcription elongation from RNA polymerase I promoter)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016570"(histone modification)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0031126"("sno(s)RNA 3'-end processing")|go:"GO:0031938"(obsolete regulation of chromatin silencing at telomere)|go:"GO:0035327"|go:"GO:0045142"(triplex DNA binding)|go:"GO:0051569"(regulation of histone H3-K4 methylation)|go:"GO:0060260"(regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0090262"(regulation of transcription-coupled nucleotide-excision repair)|go:"GO:1901525"(negative regulation of mitophagy)|go:"GO:1990269"(RNA polymerase II C-terminal domain phosphoserine binding)|go:"GO:2001165"(positive regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues)|go:"GO:2001173"(regulation of histone H2B conserved C-terminal lysine ubiquitination)|go:"GO:2001209"(positive regulation of transcription elongation from RNA polymerase I promoter)|go:"GO:2001255"(positive regulation of histone H3-K36 trimethylation)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR031101|rcsb pdb:5ZYP|reactome:R-SCE-674695|reactome:R-SCE-75955	-	-	crc64:F794ECBAD26D4820	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:mTRMzWB45dZojaB1ZrsaQRT48YQ9606	rogid:85qAqldtQL8T7JBgNxrvAYtHhd0559292	intact-crc:0CFA5F977E614ADB|rigid:FxzaTQsvu4zvbC5gJ0sb6VL7IaU	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P40507	uniprotkb:Q5VWX1	intact:EBI-25083|uniprotkb:D6VVK5|ensemblfungi:YIL079C	intact:EBI-742808|uniprotkb:Q8TCZ4|uniprotkb:Q8N4I4|uniprotkb:A8K7M8|ensembl:ENSP00000281156	psi-mi:air1_yeast(display_long)|uniprotkb:Arginine methyltransferase-interacting RING finger protein 1(gene name synonym)|uniprotkb:AIR1(gene name)|psi-mi:AIR1(display_short)|uniprotkb:YIL079C(locus name)	psi-mi:khdr2_human(display_long)|uniprotkb:SLM1(gene name synonym)|uniprotkb:Sam68-like mammalian protein 1(gene name synonym)|uniprotkb:KHDRBS2(gene name)|psi-mi:KHDRBS2(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552080|imex:IM-24995-3591	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012186.1|sgd:S000001341|mint:P40507|dip:DIP-2700N|ensemblfungi:YIL079C(gene)|ensemblfungi:YIL079C_mRNA(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031499"(TRAMP complex)|go:"GO:0043629"(ncRNA polyadenylation)|go:"GO:0071031"(nuclear mRNA surveillance of mRNA 3'-end processing)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071036"(nuclear polyadenylation-dependent snoRNA catabolic process)|go:"GO:0071037"(nuclear polyadenylation-dependent snRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071039"(nuclear polyadenylation-dependent CUT catabolic process)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR016713("Poly(A) polymerase complex, Air1/2")|interpro:IPR036875	refseq:NP_689901.2|ensembl:ENSG00000112232(gene)|ensembl:ENST00000281156(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008143"("poly(A) binding")|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0017124"(SH3 domain binding)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR032335|interpro:IPR032571|interpro:IPR036612|reactome:R-HSA-8849468	-	crc64:3CA920FA1204EC9C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:myPxXwP+mJgvoh50PLYk2Q3GMh4559292	rogid:IfFvZO2dIAo0Sdx+BUb5c8F7aQY9606	intact-crc:7ABC7CD54ACACF99|rigid:f2MNvYVqYGJ5XmyCqWbdv28GSI0	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q5VWX1	uniprotkb:P36084	intact:EBI-742808|uniprotkb:Q8TCZ4|uniprotkb:Q8N4I4|uniprotkb:A8K7M8|ensembl:ENSP00000281156	intact:EBI-11612|ensemblfungi:YKL074C|uniprotkb:D6VXL2	psi-mi:khdr2_human(display_long)|uniprotkb:SLM1(gene name synonym)|uniprotkb:Sam68-like mammalian protein 1(gene name synonym)|uniprotkb:KHDRBS2(gene name)|psi-mi:KHDRBS2(display_short)	psi-mi:mud2_yeast(display_long)|uniprotkb:MUD2(gene name)|psi-mi:MUD2(display_short)|uniprotkb:YKL358(orf name)|uniprotkb:YKL074C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552076|imex:IM-24995-3590	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_689901.2|ensembl:ENSG00000112232(gene)|ensembl:ENST00000281156(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008143"("poly(A) binding")|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0017124"(SH3 domain binding)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR032335|interpro:IPR032571|interpro:IPR036612|reactome:R-HSA-8849468	go:"GO:0000243"(commitment complex)|go:"GO:0000348"(mRNA branch site recognition)|go:"GO:0003729"(mRNA binding)|go:"GO:0008187"(poly-pyrimidine tract binding)|go:"GO:0016607"(nuclear speck)|ensemblfungi:YKL074C(gene)|go:"GO:0030628"(pre-mRNA 3'-splice site binding)|go:"GO:0045131"(pre-mRNA branch point binding)|go:"GO:0071004"(U2-type prespliceosome)|ensemblfungi:YKL074C_mRNA(transcript)|go:"GO:0089701"(U2AF complex)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|refseq:NP_012849.1|sgd:S000001557|mint:P36084|dip:DIP-758N	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:IfFvZO2dIAo0Sdx+BUb5c8F7aQY9606	rogid:l/aBULMxdezuufNxUE5qqnYEN1Y559292	intact-crc:13F4846E12B9E3B0|rigid:dOhlVPfRR+6wCHG1eO4oovEzEsw	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P53286	uniprotkb:Q5VWN6	intact:EBI-3796|uniprotkb:D6VUS2|ensemblfungi:YGR142W	intact:EBI-745958|uniprotkb:Q2YD91|uniprotkb:Q5VWN5|uniprotkb:Q6ZRQ8|uniprotkb:Q8IVG4|uniprotkb:Q9BUZ7|uniprotkb:Q9H5J9|uniprotkb:Q9H7A4|uniprotkb:Q9H996|uniprotkb:Q9NXA1|intact:EBI-28974916|ensembl:ENSP00000328426	psi-mi:btn2_yeast(display_long)|uniprotkb:YGR142W(locus name)|uniprotkb:BTN2(gene name)|psi-mi:BTN2(display_short)|uniprotkb:Batten disease protein 2(gene name synonym)	psi-mi:taso2_human(display_long)|uniprotkb:TASOR2(gene name)|psi-mi:TASOR2(display_short)|uniprotkb:C10orf18(gene name synonym)|uniprotkb:FAM208B(gene name synonym)|uniprotkb:KIAA2006(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552072|imex:IM-24995-3589	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003374|refseq:NP_011658.3|dip:DIP-5534N|mint:P53286|ensemblfungi:YGR142W(gene)|ensemblfungi:YGR142W_mRNA(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005634"(nucleus)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006865"(amino acid transport)|go:"GO:0006885"(regulation of pH)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051087"(chaperone binding)|go:"GO:0140311"(protein sequestering activity)	refseq:NP_060252.4|ensembl:ENSP00000328426|refseq:XP_011517827.1|refseq:XP_016871852.1|refseq:XP_016871854.1|ensembl:ENSG00000108021(gene)|ensembl:ENST00000328090(transcript)|go:"GO:0005829"(cytosol)|interpro:IPR022168|interpro:IPR022188|mint:Q5VWN6|go:"GO:0005654"(nucleoplasm)|refseq:XP_005252532.1|refseq:XP_005252537.1|refseq:XP_005252538.1|refseq:XP_005252539.1|refseq:NP_001308712.1|refseq:NP_001308713.1|refseq:NP_001308714.1	-	crc64:E7AE1EB1E3612F3E	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Cu27xkwGMNyS4zLvUaG1UeH2mE0559292	rogid:mTRMzWB45dZojaB1ZrsaQRT48YQ9606	intact-crc:8C675CB1FB4C7078|rigid:7+7MsobuGDkG6QcBDTEJk0uu9fc	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q5VWX1	uniprotkb:P38340	intact:EBI-742808|uniprotkb:Q8TCZ4|uniprotkb:Q8N4I4|uniprotkb:A8K7M8|ensembl:ENSP00000281156	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:khdr2_human(display_long)|uniprotkb:SLM1(gene name synonym)|uniprotkb:Sam68-like mammalian protein 1(gene name synonym)|uniprotkb:KHDRBS2(gene name)|psi-mi:KHDRBS2(display_short)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552084|imex:IM-24995-3592	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_689901.2|ensembl:ENSG00000112232(gene)|ensembl:ENST00000281156(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008143"("poly(A) binding")|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0017124"(SH3 domain binding)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR032335|interpro:IPR032571|interpro:IPR036612|reactome:R-HSA-8849468	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F	-	-	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:IfFvZO2dIAo0Sdx+BUb5c8F7aQY9606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:2C39254B2626458A|rigid:0T4js7J5FoPVuVYAEbM1jIc36Ic	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q6RW13-2	uniprotkb:Q12259	intact:EBI-11522760|ensembl:ENSP00000365816	intact:EBI-30776|uniprotkb:D6VYA8|ensemblfungi:YLR108C	psi-mi:q6rw13-2(display_long)|uniprotkb:AGTRAP(gene name)|psi-mi:AGTRAP(display_short)|uniprotkb:AT1 receptor-associated protein(gene name synonym)|uniprotkb:ATRAP(gene name synonym)	psi-mi:yl108_yeast(display_long)|uniprotkb:L2913(orf name)|uniprotkb:YLR108C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552136|imex:IM-24995-3605	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000177674(gene)|ensembl:ENST00000376629(transcript)|intact:EBI-741181(isoform-parent)|uniprotkb:Q6RW13-2(isoform-parent)	refseq:NP_013209.1|sgd:S000004098|dip:DIP-4075N|ensemblfungi:YLR108C(gene)|ensemblfungi:YLR108C_mRNA(transcript)|go:"GO:0005634"(nucleus)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:PNzVis/8puQZBJ562gCqZKc078s9606	rogid:CzknxXhhvgMp3J0/oi197EgZ05U559292	intact-crc:C02C5E7DD7CE5DC7|rigid:Y/xDLctUWzrTeJsAQfmQs5tk0h8	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q6RW13-2	uniprotkb:P04819	intact:EBI-11522760|ensembl:ENSP00000365816	intact:EBI-5991|uniprotkb:Q12736|uniprotkb:D6VRI7|ensemblfungi:YDL164C	psi-mi:q6rw13-2(display_long)|uniprotkb:AGTRAP(gene name)|psi-mi:AGTRAP(display_short)|uniprotkb:AT1 receptor-associated protein(gene name synonym)|uniprotkb:ATRAP(gene name synonym)	psi-mi:dnli1_yeast(display_long)|uniprotkb:YDL164C(locus name)|uniprotkb:CDC9(gene name)|psi-mi:CDC9(display_short)|uniprotkb:DNA ligase I(gene name synonym)|uniprotkb:Polydeoxyribonucleotide synthase [ATP] 1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552132|imex:IM-24995-3604	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000177674(gene)|ensembl:ENST00000376629(transcript)|intact:EBI-741181(isoform-parent)|uniprotkb:Q6RW13-2(isoform-parent)	refseq:NP_010117.1|sgd:S000002323|dip:DIP-5630N|mint:P04819|ensemblfungi:YDL164C(gene)|ensemblfungi:YDL164C_mRNA(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003677"(DNA binding)|go:"GO:0003910"("DNA ligase (ATP) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006266"(DNA ligation)|go:"GO:0006273"(lagging strand elongation)|go:"GO:0006284"(base-excision repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0035753"(maintenance of DNA trinucleotide repeats)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:0071897"(DNA biosynthetic process)|go:"GO:1903461"(Okazaki fragment processing involved in mitotic DNA replication)|interpro:IPR000977(ATP-dependent DNA ligase)|interpro:IPR012308(DNA ligase, N-terminal)|interpro:IPR012309(ATP dependent DNA ligase, C-terminal)|interpro:IPR012310(ATP dependent DNA ligase, central)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR016059(ATP-dependent DNA ligase, conserved site)|interpro:IPR036599|rcsb pdb:2OD8|reactome:R-SCE-5358565|reactome:R-SCE-5358606|reactome:R-SCE-6782210|reactome:R-SCE-69183	-	-	crc64:B7C2ECAF5C61CAE7	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:PNzVis/8puQZBJ562gCqZKc078s9606	rogid:sl00ubCmkTFwW2bznucqEF60I3M559292	intact-crc:FC81A01B91A31DEE|rigid:BQ0xwnjpl3+ZguuTGK0dY4JVs44	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q02724	uniprotkb:Q6RW13-2	intact:EBI-20050|uniprotkb:D6W3Z2|ensemblfungi:YPL020C	intact:EBI-11522760|ensembl:ENSP00000365816	psi-mi:ulp1_yeast(display_long)|uniprotkb:ULP1(gene name)|psi-mi:ULP1(display_short)|uniprotkb:LPB11C(orf name)|uniprotkb:YPL020C(locus name)	psi-mi:q6rw13-2(display_long)|uniprotkb:AGTRAP(gene name)|psi-mi:AGTRAP(display_short)|uniprotkb:AT1 receptor-associated protein(gene name synonym)|uniprotkb:ATRAP(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552128|imex:IM-24995-3603	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015305.1|sgd:S000005941|ensemblfungi:YPL020C(gene)|ensemblfungi:YPL020C_mRNA(transcript)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005730"(nucleolus)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0016926"(protein desumoylation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070140"(SUMO-specific isopeptidase activity)|interpro:IPR003653(Peptidase C48, SUMO/Sentrin/Ubl1)|interpro:IPR038765|rcsb pdb:1EUV|rcsb pdb:2HKP|rcsb pdb:2HL8|rcsb pdb:2HL9|rcsb pdb:5H2V|rcsb pdb:5H2W|rcsb pdb:5H2X|reactome:R-SCE-3065679|reactome:R-SCE-6791226|dip:DIP-4041N|mint:Q02724	ensembl:ENSG00000177674(gene)|ensembl:ENST00000376629(transcript)|intact:EBI-741181(isoform-parent)|uniprotkb:Q6RW13-2(isoform-parent)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:H9B4qZf/ZMbHr7u4hbtR4fzz0ec559292	rogid:PNzVis/8puQZBJ562gCqZKc078s9606	intact-crc:A9A3C594C157ADE3|rigid:71n37RR9MkaYxPdD0E2912OYv14	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q6RW13-2	uniprotkb:P18496	intact:EBI-11522760|ensembl:ENSP00000365816	intact:EBI-3323|uniprotkb:Q06020|uniprotkb:D6VZ28|ensemblfungi:YLR393W	psi-mi:q6rw13-2(display_long)|uniprotkb:AGTRAP(gene name)|psi-mi:AGTRAP(display_short)|uniprotkb:AT1 receptor-associated protein(gene name synonym)|uniprotkb:ATRAP(gene name synonym)	psi-mi:atp10_yeast(display_long)|uniprotkb:ATP10(gene name)|psi-mi:ATP10(display_short)|uniprotkb:L8084.8(orf name)|uniprotkb:YLR393W(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552124|imex:IM-24995-3602	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000177674(gene)|ensembl:ENST00000376629(transcript)|intact:EBI-741181(isoform-parent)|uniprotkb:Q6RW13-2(isoform-parent)	refseq:NP_013497.1|sgd:S000004385|dip:DIP-4641N|ensemblfungi:YLR393W(gene)|ensemblfungi:YLR393W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0032592"(integral component of mitochondrial membrane)|go:"GO:0033615"(mitochondrial proton-transporting ATP synthase complex assembly)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR007849(ATP10)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:PNzVis/8puQZBJ562gCqZKc078s9606	rogid:3LfbKFFgOegWNYA+M/jOd0ORiAk559292	intact-crc:D6265E1C69434B4B|rigid:RjK1ml/F9cQO92ApAhPt9NTHlcc	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q6RW13-2	uniprotkb:P24280	intact:EBI-11522760|ensembl:ENSP00000365816	intact:EBI-16535|uniprotkb:D6VZQ3|ensemblfungi:YMR079W	psi-mi:q6rw13-2(display_long)|uniprotkb:AGTRAP(gene name)|psi-mi:AGTRAP(display_short)|uniprotkb:AT1 receptor-associated protein(gene name synonym)|uniprotkb:ATRAP(gene name synonym)	psi-mi:sec14_yeast(display_long)|uniprotkb:SEC14(gene name)|psi-mi:SEC14(display_short)|uniprotkb:Phosphatidylinositol/phosphatidylcholine transfer protein(gene name synonym)|uniprotkb:PIT1(gene name synonym)|uniprotkb:YM9582.04(orf name)|uniprotkb:YMR079W(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552120|imex:IM-24995-3601	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000177674(gene)|ensembl:ENST00000376629(transcript)|intact:EBI-741181(isoform-parent)|uniprotkb:Q6RW13-2(isoform-parent)	refseq:NP_013796.1|sgd:S000004684|ensemblfungi:YMR079W(gene)|ensemblfungi:YMR079W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0008525"(phosphatidylcholine transporter activity)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0008526"(phosphatidylinositol transfer activity)|go:"GO:0015914"(phospholipid transport)|go:"GO:0030437"(ascospore formation)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0046488"(phosphatidylinositol metabolic process)|go:"GO:0048194"(Golgi vesicle budding)|go:"GO:1901352"(negative regulation of phosphatidylglycerol biosynthetic process)|go:"GO:2001246"(negative regulation of phosphatidylcholine biosynthetic process)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR011074(Phosphatidylinositol transfer protein-like, N-terminal)|interpro:IPR036273|interpro:IPR036865|rcsb pdb:1AUA|rcsb pdb:6F0E|dip:DIP-1610N|mint:P24280	-	-	crc64:CCB69404A8A0963B	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:PNzVis/8puQZBJ562gCqZKc078s9606	rogid:6KY0fOn92xmZkZBq10NHRCWtd7w559292	intact-crc:877E36A08752FF03|rigid:Om2ejsdhmZcM+TfO/PN828HwyqI	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P53286	uniprotkb:Q6P1W5	intact:EBI-3796|uniprotkb:D6VUS2|ensemblfungi:YGR142W	intact:EBI-946029|uniprotkb:B3KVT1|uniprotkb:Q96IC8|ensembl:ENSP00000435634|uniprotkb:D3DPR3|uniprotkb:E9PJ76	psi-mi:btn2_yeast(display_long)|uniprotkb:YGR142W(locus name)|uniprotkb:BTN2(gene name)|psi-mi:BTN2(display_short)|uniprotkb:Batten disease protein 2(gene name synonym)	psi-mi:ca094_human(display_long)|uniprotkb:C1orf94(gene name)|psi-mi:C1orf94(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552116|imex:IM-24995-3600	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003374|refseq:NP_011658.3|dip:DIP-5534N|mint:P53286|ensemblfungi:YGR142W(gene)|ensemblfungi:YGR142W_mRNA(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005634"(nucleus)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006865"(amino acid transport)|go:"GO:0006885"(regulation of pH)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051087"(chaperone binding)|go:"GO:0140311"(protein sequestering activity)	refseq:NP_001128206.1|refseq:NP_116273.2|ensembl:ENSG00000142698(gene)|ensembl:ENST00000488417(transcript)|interpro:IPR031496	-	crc64:E7AE1EB1E3612F3E	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Cu27xkwGMNyS4zLvUaG1UeH2mE0559292	rogid:y1o4xWvTl2CBA1J7jsP7y8ZjLzM9606	intact-crc:66C90943AACA2A91|rigid:rwo3wJUtUQCT6celj1ZqUnTbioI	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P38868	uniprotkb:Q6P1W5	intact:EBI-24840|uniprotkb:A0A1S0T004|ensemblfungi:YHR180W	intact:EBI-946029|uniprotkb:B3KVT1|uniprotkb:Q96IC8|ensembl:ENSP00000435634|uniprotkb:D3DPR3|uniprotkb:E9PJ76	psi-mi:yhy0_yeast(display_long)|uniprotkb:YHR180W(locus name)	psi-mi:ca094_human(display_long)|uniprotkb:C1orf94(gene name)|psi-mi:C1orf94(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552112|imex:IM-24995-3599	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000001223|dip:DIP-4332N|ensemblfungi:YHR180W(gene)|ensemblfungi:YHR180W_mRNA(transcript)|go:"GO:0016021"(integral component of membrane)	refseq:NP_001128206.1|refseq:NP_116273.2|ensembl:ENSG00000142698(gene)|ensembl:ENST00000488417(transcript)|interpro:IPR031496	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:E7zJN1iVyb08WvBGa7NXcqw4sqw559292	rogid:y1o4xWvTl2CBA1J7jsP7y8ZjLzM9606	intact-crc:8669D901EE592322|rigid:hVpdiBz4Xv9ToxTQ5x2xu/Sj0QU	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q6P1W5	uniprotkb:Q04307	intact:EBI-946029|uniprotkb:B3KVT1|uniprotkb:Q96IC8|ensembl:ENSP00000435634|uniprotkb:D3DPR3|uniprotkb:E9PJ76	intact:EBI-15858|uniprotkb:Q2VQW5|ensemblfungi:YDR045C|uniprotkb:D6VS33	psi-mi:ca094_human(display_long)|uniprotkb:C1orf94(gene name)|psi-mi:C1orf94(display_short)	psi-mi:rpc10_yeast(display_long)|uniprotkb:RPC11(gene name)|psi-mi:RPC11(display_short)|uniprotkb:YDR045C(locus name)|uniprotkb:YD9609.01C(orf name)|uniprotkb:RNA polymerase III subunit C11(gene name synonym)|uniprotkb:DNA-directed RNA polymerases III 12.5 kDa polypeptide(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552108|imex:IM-24995-3598	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001128206.1|refseq:NP_116273.2|ensembl:ENSG00000142698(gene)|ensembl:ENST00000488417(transcript)|interpro:IPR031496	ensemblfungi:YDR045C(gene)|refseq:NP_010330.1|sgd:S000002452|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006386"(termination of RNA polymerase III transcription)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042779"(tRNA 3'-trailer cleavage)|go:"GO:0042797"(tRNA transcription by RNA polymerase III)|interpro:IPR001222(Zinc finger, TFIIS-type)|interpro:IPR001529(DNA-directed RNA polymerase, M/15 kDa subunit)|interpro:IPR012164(DNA-directed RNA polymerase, subunit C11/M/9)|interpro:IPR019761|interpro:IPR034014|rcsb pdb:3QT1|ensemblfungi:YDR045C_mRNA(transcript)|rcsb pdb:5FJ8|rcsb pdb:5FJ9|rcsb pdb:5FJA|rcsb pdb:6CNB|rcsb pdb:6CNC|rcsb pdb:6CND|rcsb pdb:6CNF|rcsb pdb:6EU0|rcsb pdb:6EU2|rcsb pdb:6EU3|rcsb pdb:6F40|rcsb pdb:6F41|rcsb pdb:6F42|rcsb pdb:6F44|rcsb pdb:6TUT|reactome:R-SCE-76061|reactome:R-SCE-76066|rcsb pdb:6EU1|dip:DIP-887N|mint:Q04307	-	-	crc64:E4AA802EC9F92230	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:y1o4xWvTl2CBA1J7jsP7y8ZjLzM9606	rogid:G2fIQbptabHIUI224iPtTJF+dIs559292	intact-crc:E1D422F4778058E8|rigid:lAblKOzNr1tiUBq1jkBoEwAh1X0	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P40014	uniprotkb:Q6P1W5	intact:EBI-22458|uniprotkb:D3DLR6|ensemblfungi:YER018C	intact:EBI-946029|uniprotkb:B3KVT1|uniprotkb:Q96IC8|ensembl:ENSP00000435634|uniprotkb:D3DPR3|uniprotkb:E9PJ76	psi-mi:spc25_yeast(display_long)|uniprotkb:YER018C(locus name)|uniprotkb:SPC25(gene name)|psi-mi:SPC25(display_short)	psi-mi:ca094_human(display_long)|uniprotkb:C1orf94(gene name)|psi-mi:C1orf94(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552104|imex:IM-24995-3597	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010934.3|sgd:S000000820|dip:DIP-2990N|mint:P40014|ensemblfungi:YER018C(gene)|ensemblfungi:YER018C_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0051301"(cell division)|go:"GO:0098653"(centromere clustering)|interpro:IPR038066|rcsb pdb:2FTX|rcsb pdb:2FV4|rcsb pdb:4GEQ|rcsb pdb:5T6J|rcsb pdb:5TCS|rcsb pdb:5TD8|rcsb pdb:7KDF	refseq:NP_001128206.1|refseq:NP_116273.2|ensembl:ENSG00000142698(gene)|ensembl:ENST00000488417(transcript)|interpro:IPR031496	-	crc64:1BED6CCFF330A5D8	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:i5gKRZA7GAjnCVzuX/qP8YmpQRA559292	rogid:y1o4xWvTl2CBA1J7jsP7y8ZjLzM9606	intact-crc:AD7C66972F79B481|rigid:7whOMEJOuuXKJBnESrRfZGxlaI0	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q6RW13-2	uniprotkb:P32453	intact:EBI-11522760|ensembl:ENSP00000365816	intact:EBI-3306|uniprotkb:D6W0N0|ensemblfungi:YNL315C	psi-mi:q6rw13-2(display_long)|uniprotkb:AGTRAP(gene name)|psi-mi:AGTRAP(display_short)|uniprotkb:AT1 receptor-associated protein(gene name synonym)|uniprotkb:ATRAP(gene name synonym)	psi-mi:atp11_yeast(display_long)|uniprotkb:ATP11(gene name)|psi-mi:ATP11(display_short)|uniprotkb:N0357(orf name)|uniprotkb:YNL315C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552144|imex:IM-24995-3607	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000177674(gene)|ensembl:ENST00000376629(transcript)|intact:EBI-741181(isoform-parent)|uniprotkb:Q6RW13-2(isoform-parent)	refseq:NP_014084.1|sgd:S000005259|dip:DIP-3026N|mint:P32453|ensemblfungi:YNL315C(gene)|ensemblfungi:YNL315C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0033615"(mitochondrial proton-transporting ATP synthase complex assembly)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR010591(ATP11)	-	-	crc64:61109AA4D338F2CD	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:PNzVis/8puQZBJ562gCqZKc078s9606	rogid:JsQu6HtKtGqAVhHzaPVc8IMYdqM559292	intact-crc:E81DD303BA7D67E9|rigid:Gl/aNuCOn/VnsjWxu27bfTvUiH8	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q6RW13-2	uniprotkb:P38815	intact:EBI-11522760|ensembl:ENSP00000365816	intact:EBI-24665|uniprotkb:D3DL55|ensemblfungi:YHR105W	psi-mi:q6rw13-2(display_long)|uniprotkb:AGTRAP(gene name)|psi-mi:AGTRAP(display_short)|uniprotkb:AT1 receptor-associated protein(gene name synonym)|uniprotkb:ATRAP(gene name synonym)	psi-mi:ypt35_yeast(display_long)|uniprotkb:YHR105W(locus name)|uniprotkb:YPT35(gene name)|psi-mi:YPT35(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552148|imex:IM-24995-3608	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000177674(gene)|ensembl:ENST00000376629(transcript)|intact:EBI-741181(isoform-parent)|uniprotkb:Q6RW13-2(isoform-parent)	refseq:NP_011973.1|sgd:S000001147|dip:DIP-1881N|ensemblfungi:YHR105W(gene)|ensemblfungi:YHR105W_mRNA(transcript)|go:"GO:0005768"(endosome)|go:"GO:0010008"(endosome membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|interpro:IPR001683(Phox-like)|interpro:IPR036871|interpro:IPR037917	-	-	crc64:2ADD21AF107094DC	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:PNzVis/8puQZBJ562gCqZKc078s9606	rogid:fUTJG8BaTveH3zB/0W1vNh4BU2Y559292	intact-crc:DE84945733C82926|rigid:TljLFTagZAaBJcwIVz4e6tNIXTU	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q6RW13-2	uniprotkb:P49017	intact:EBI-11522760|ensembl:ENSP00000365816	intact:EBI-4937|ensemblfungi:YML110C|uniprotkb:D6W0H4	psi-mi:q6rw13-2(display_long)|uniprotkb:AGTRAP(gene name)|psi-mi:AGTRAP(display_short)|uniprotkb:AT1 receptor-associated protein(gene name synonym)|uniprotkb:ATRAP(gene name synonym)	psi-mi:coq5_yeast(display_long)|uniprotkb:COQ5(gene name)|psi-mi:COQ5(display_short)|uniprotkb:DBI56(gene name synonym)|uniprotkb:YML110C(locus name)|uniprotkb:YM8339.09C(orf name)|uniprotkb:Ubiquinone biosynthesis methyltransferase COQ5(gene name synonym)|uniprotkb:2-hexaprenyl-6-methoxy-1,4-benzoquinol methyltransferase(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552152|imex:IM-24995-3609	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000177674(gene)|ensembl:ENST00000376629(transcript)|intact:EBI-741181(isoform-parent)|uniprotkb:Q6RW13-2(isoform-parent)	ensemblfungi:YML110C(gene)|ensemblfungi:YML110C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006744"(ubiquinone biosynthetic process)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0009060"(aerobic respiration)|go:"GO:0031314"(extrinsic component of mitochondrial inner membrane)|go:"GO:0032259"(methylation)|go:"GO:0043333"(2-octaprenyl-6-methoxy-1,4-benzoquinone methylase activity)|go:"GO:0043334"(2-hexaprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity)|interpro:IPR004033(UbiE/COQ5 methyltransferase)|interpro:IPR023576|interpro:IPR029063|rcsb pdb:4OBW|rcsb pdb:4OBX|refseq:NP_013597.1|sgd:S000004578|dip:DIP-1639N	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:PNzVis/8puQZBJ562gCqZKc078s9606	rogid:rgHxCUvCLn3xoq9Jv4EMhFupCmI559292	intact-crc:64D839FDAF9159CD|rigid:2l2i9Qj0Zo0jzW6ribbZQlzU90w	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P38340	uniprotkb:Q6RW13-2	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-11522760|ensembl:ENSP00000365816	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:q6rw13-2(display_long)|uniprotkb:AGTRAP(gene name)|psi-mi:AGTRAP(display_short)|uniprotkb:AT1 receptor-associated protein(gene name synonym)|uniprotkb:ATRAP(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552156|imex:IM-24995-3610	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F	ensembl:ENSG00000177674(gene)|ensembl:ENST00000376629(transcript)|intact:EBI-741181(isoform-parent)|uniprotkb:Q6RW13-2(isoform-parent)	-	crc64:66699F37B0013088	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:PNzVis/8puQZBJ562gCqZKc078s9606	intact-crc:9F77E5D4AD0B0132|rigid:A+Xt1mCM+n7/uS0ETA2CRRNAvNY	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q12161	uniprotkb:Q7L190	intact:EBI-34372|uniprotkb:D6W213|ensemblfungi:YOL054W	intact:EBI-710457|intact:EBI-28975079|ensembl:ENSP00000335306|uniprotkb:Q9H9N5|uniprotkb:Q9NVI6|uniprotkb:A8K4M7	psi-mi:psh1_yeast(display_long)|uniprotkb:PSH1(gene name)|psi-mi:PSH1(display_short)|uniprotkb:POB3/SPT16 histone-associated protein 1(gene name synonym)|uniprotkb:O1263(orf name)|uniprotkb:YOL054W(locus name)	psi-mi:dppa4_human(display_long)|uniprotkb:DPPA4(gene name)|psi-mi:DPPA4(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552160|imex:IM-24995-3611	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014587.1|sgd:S000005415|mint:Q12161|dip:DIP-6481N|ensemblfungi:YOL054W(gene)|ensemblfungi:YOL054W_mRNA(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907	refseq:NP_060659.3|mint:Q7L190|reactome:R-HSA-2892247|ensembl:ENSG00000121570(gene)|ensembl:ENST00000335658(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0048731"(system development)|go:"GO:0060484"(lung-associated mesenchyme development)|interpro:IPR025891|interpro:IPR025892|interpro:IPR039590|interpro:IPR039836|ensembl:ENSP00000335306	-	crc64:CE0ECBCB6D465554	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:AvPMRd/GjfaTyQjEfMPhBVcvOs4559292	rogid:WKqQ0ipAAfKsDRuXJhtTWJcROdc9606	intact-crc:D5B54528D3FCC861|rigid:ntfXmWM1RHuN/MhAxByifxCsJw4	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P00431	uniprotkb:Q6RW13-2	intact:EBI-4389|uniprotkb:Q6Q5M9|uniprotkb:D6VXC7|ensemblfungi:YKR066C	intact:EBI-11522760|ensembl:ENSP00000365816	psi-mi:ccpr_yeast(display_long)|uniprotkb:CCP1(gene name)|psi-mi:CCP1(display_short)|uniprotkb:CCP(gene name synonym)|uniprotkb:CPO(gene name synonym)|uniprotkb:YKR066C(locus name)	psi-mi:q6rw13-2(display_long)|uniprotkb:AGTRAP(gene name)|psi-mi:AGTRAP(display_short)|uniprotkb:AT1 receptor-associated protein(gene name synonym)|uniprotkb:ATRAP(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552140|imex:IM-24995-3606	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012992.1|sgd:S000001774|dip:DIP-6251N|ensemblfungi:YKR066C(gene)|ensemblfungi:YKR066C_mRNA(transcript)|go:"GO:0000302"(response to reactive oxygen species)|go:"GO:0004130"(cytochrome-c peroxidase activity)|go:"GO:0004601"(peroxidase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0020037"(heme binding)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0046872"(metal ion binding)|interpro:IPR002016(Haem peroxidase, plant/fungal/bacterial)|interpro:IPR002207(Plant ascorbate peroxidase)|interpro:IPR010255(Haem peroxidase)|interpro:IPR019793|interpro:IPR019794|interpro:IPR044831|rcsb pdb:1A2F|rcsb pdb:1A2G|rcsb pdb:1AA4|rcsb pdb:1AC4|rcsb pdb:1AC8|rcsb pdb:1AEB|rcsb pdb:1AED|rcsb pdb:1AEE|rcsb pdb:1AEF|rcsb pdb:1AEG|rcsb pdb:1AEH|rcsb pdb:1AEJ|rcsb pdb:1AEK|rcsb pdb:1AEM|rcsb pdb:1AEN|rcsb pdb:1AEO|rcsb pdb:1AEQ|rcsb pdb:1AES|rcsb pdb:1AET|rcsb pdb:1AEU|rcsb pdb:1AEV|rcsb pdb:1BEJ|rcsb pdb:1BEK|rcsb pdb:1BEM|rcsb pdb:1BEP|rcsb pdb:1BEQ|rcsb pdb:1BES|rcsb pdb:1BJ9|rcsb pdb:1BVA|rcsb pdb:1CCA|rcsb pdb:1CCB|rcsb pdb:1CCC|rcsb pdb:1CCE|rcsb pdb:1CCG|rcsb pdb:1CCI|rcsb pdb:1CCJ|rcsb pdb:1CCK|rcsb pdb:1CCL|rcsb pdb:1CCP|rcsb pdb:1CMP|rcsb pdb:1CMQ|rcsb pdb:1CMT|rcsb pdb:1CPD|rcsb pdb:1CPE|rcsb pdb:1CPF|rcsb pdb:1CPG|rcsb pdb:1CYF|rcsb pdb:1DCC|rcsb pdb:1DJ1|rcsb pdb:1DJ5|rcsb pdb:1DS4|rcsb pdb:1DSE|rcsb pdb:1DSG|rcsb pdb:1DSO|rcsb pdb:1DSP|rcsb pdb:1EBE|rcsb pdb:1JCI|rcsb pdb:1JDR|rcsb pdb:1KOK|rcsb pdb:1KRJ|rcsb pdb:1KXM|rcsb pdb:1KXN|rcsb pdb:1MK8|rcsb pdb:1MKQ|rcsb pdb:1MKR|rcsb pdb:1ML2|rcsb pdb:1RYC|rcsb pdb:1S6V|rcsb pdb:1S73|rcsb pdb:1SBM|rcsb pdb:1SDQ|rcsb pdb:1SOG|rcsb pdb:1STQ|rcsb pdb:1U74|rcsb pdb:1U75|rcsb pdb:1Z53|rcsb pdb:1ZBY|rcsb pdb:1ZBZ|rcsb pdb:2ANZ|rcsb pdb:2AQD|rcsb pdb:2AS1|rcsb pdb:2AS2|rcsb pdb:2AS3|rcsb pdb:2AS4|rcsb pdb:2AS6|rcsb pdb:2B0Z|rcsb pdb:2B10|rcsb pdb:2B11|rcsb pdb:2B12|rcsb pdb:2BCN|rcsb pdb:2CCP|rcsb pdb:2CEP|rcsb pdb:2CYP|rcsb pdb:2EUN|rcsb pdb:2EUO|rcsb pdb:2EUP|rcsb pdb:2EUQ|rcsb pdb:2EUR|rcsb pdb:2EUS|rcsb pdb:2EUT|rcsb pdb:2EUU|rcsb pdb:2GB8|rcsb pdb:2IA8|rcsb pdb:2ICV|rcsb pdb:2JTI|rcsb pdb:2N18|rcsb pdb:2PCB|rcsb pdb:2PCC|rcsb pdb:2RBT|rcsb pdb:2RBU|rcsb pdb:2RBV|rcsb pdb:2RBW|rcsb pdb:2RBX|rcsb pdb:2RBY|rcsb pdb:2RBZ|rcsb pdb:2RC0|rcsb pdb:2RC1|rcsb pdb:2RC2|rcsb pdb:2V23|rcsb pdb:2V2E|rcsb pdb:2X07|rcsb pdb:2X08|rcsb pdb:2XIL|rcsb pdb:2XJ5|rcsb pdb:2XJ8|rcsb pdb:2Y5A|rcsb pdb:2YCG|rcsb pdb:3CCP|rcsb pdb:3CCX|rcsb pdb:3E2N|rcsb pdb:3E2O|rcsb pdb:3EXB|rcsb pdb:3M23|rcsb pdb:3M25|rcsb pdb:3M26|rcsb pdb:3M27|rcsb pdb:3M28|rcsb pdb:3M29|rcsb pdb:3M2A|rcsb pdb:1CMU|rcsb pdb:3M2B|rcsb pdb:3M2C|rcsb pdb:3M2D|rcsb pdb:3M2E|rcsb pdb:3M2F|rcsb pdb:3M2G|rcsb pdb:3M2H|rcsb pdb:3M2I|rcsb pdb:3R98|rcsb pdb:3R99|rcsb pdb:4A6Z|rcsb pdb:4A71|rcsb pdb:4A78|rcsb pdb:4A7M|rcsb pdb:4CCP|rcsb pdb:4CCX|rcsb pdb:4CVI|rcsb pdb:4CVJ|rcsb pdb:4JB4|rcsb pdb:4NFG|rcsb pdb:4P4Q|rcsb pdb:4XV4|rcsb pdb:4XV5|rcsb pdb:4XV6|rcsb pdb:4XV7|rcsb pdb:4XV8|rcsb pdb:4XVA|rcsb pdb:5CCP|rcsb pdb:5CIB|rcsb pdb:5CIC|rcsb pdb:5CID|rcsb pdb:5CIE|rcsb pdb:5CIF|rcsb pdb:5CIG|rcsb pdb:5CIH|rcsb pdb:5D6M|rcsb pdb:5EJT|rcsb pdb:5EJX|rcsb pdb:6CCP|rcsb pdb:6H08|rcsb pdb:6P41|rcsb pdb:6P42|rcsb pdb:6P43|rcsb pdb:6Y1T|rcsb pdb:6Y2Y|rcsb pdb:7CCP	ensembl:ENSG00000177674(gene)|ensembl:ENST00000376629(transcript)|intact:EBI-741181(isoform-parent)|uniprotkb:Q6RW13-2(isoform-parent)	-	crc64:A5D26385DA6F0A0B	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:LkPXY1wuYoCFzMQPSsAtXZrRi8w559292	rogid:PNzVis/8puQZBJ562gCqZKc078s9606	intact-crc:8139815B105AE8A0|rigid:5UDqt3eotijjhpIZik/N0KGkdIo	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P32562	uniprotkb:Q7L5A3	intact:EBI-4440|ensemblfungi:YMR001C|uniprotkb:D6VZH5	intact:EBI-745689|uniprotkb:O60377|uniprotkb:Q9BQ60|uniprotkb:Q9HAI9|uniprotkb:Q9P1Y9|ensembl:ENSP00000319897|ensembl:ENSP00000367819|ensembl:ENSP00000367823|ensembl:ENSP00000474335|ensembl:ENSP00000474833|ensembl:ENSP00000475120|uniprotkb:D3DRN5|uniprotkb:B1AML4|uniprotkb:B1AML5	psi-mi:cdc5_yeast(display_long)|uniprotkb:CDC5(gene name)|psi-mi:CDC5(display_short)|uniprotkb:MSD2(gene name synonym)|uniprotkb:PKX2(gene name synonym)|uniprotkb:YMR001C(locus name)|uniprotkb:YM8270.03C(orf name)	psi-mi:f214b_human(display_long)|uniprotkb:FAM214B(gene name)|psi-mi:FAM214B(display_short)|uniprotkb:KIAA1539(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552168|imex:IM-24995-3613	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YMR001C(gene)|ensemblfungi:YMR001C_mRNA(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0000922"(spindle pole)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0010458"(exit from mitosis)|go:"GO:0010696"(positive regulation of mitotic spindle pole body separation)|go:"GO:0019237"(centromeric DNA binding)|refseq:NP_013714.1|sgd:S000004603|reactome:R-SCE-6804115|reactome:R-SCE-156711|reactome:R-SCE-162658|reactome:R-SCE-2565942|dip:DIP-2321N|reactome:R-SCE-2500257|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0035025"(positive regulation of Rho protein signal transduction)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051301"(cell division)|go:"GO:0070194"(synaptonemal complex disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0110083"(positive regulation of protein localization to cell division site involved in mitotic actomyosin contractile ring assembly)|go:"GO:1902542"(regulation of protein localization to mitotic spindle pole body)|go:"GO:1903353"(regulation of nucleus organization)|go:"GO:1904750"(negative regulation of protein localization to nucleolus)|go:"GO:1905339"(positive regulation of cohesin unloading)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033695|interpro:IPR033701|interpro:IPR036947|rcsb pdb:6MF4|rcsb pdb:6MF5|rcsb pdb:6MF6	refseq:NP_079458.2|refseq:XP_011516339.1|refseq:XP_011516345.1|refseq:XP_011516346.1|ensembl:ENST00000603301(transcript)|ensembl:ENST00000605244(transcript)|go:"GO:0005634"(nucleus)|interpro:IPR025261|interpro:IPR033473|mint:Q7L5A3|ensembl:ENSG00000005238(gene)|ensembl:ENST00000322813(transcript)|ensembl:ENST00000378557(transcript)|ensembl:ENST00000378561(transcript)|ensembl:ENST00000488109(transcript)|refseq:NP_001304920.1|refseq:XP_005251645.1|refseq:XP_005251647.1|refseq:XP_005251648.1|refseq:XP_016870659.1	-	crc64:B5A25F1BBBEAA3DC	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:XXSkltYvBA9Zkh0Kr5s1znazUC0559292	rogid:M9Hjv238OhxmmyVQbKrX6JOYL7k9606	intact-crc:2E82A909C89DFCAA|rigid:6bX+YSG9XqF0QTwLWHdgCismuoA	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q7LHD1	uniprotkb:Q03393	intact:EBI-11537611	intact:EBI-712344|ensembl:ENSP00000280362|uniprotkb:Q8WVG8|uniprotkb:B0YJ87	psi-mi:ccw22_yeast(display_long)|uniprotkb:CCW22(gene name)|psi-mi:CCW22(display_short)|uniprotkb:YD9302.09C/YD9302.10C(orf name)|uniprotkb:YDR134C(locus name)	psi-mi:ptps_human(display_long)|uniprotkb:PTS(gene name)|psi-mi:PTS(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552172|imex:IM-24995-3614	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR025928|sgd:S000002541|go:"GO:0005576"(extracellular region)|go:"GO:0009277"(fungal-type cell wall)|go:"GO:0031225"(anchored component of membrane)	refseq:NP_000308.1|ensembl:ENSG00000150787(gene)|ensembl:ENST00000280362(transcript)|go:"GO:0003874"(6-pyruvoyltetrahydropterin synthase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006520"(cellular amino acid metabolic process)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0007417"(central nervous system development)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR007115(6-pyruvoyl tetrahydropterin synthase-related)|interpro:IPR022469|interpro:IPR022470|interpro:IPR038418|rcsb pdb:3I2B|reactome:R-HSA-1474151	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/03/16	rogid:Jrl6wg+0ObAYQSYzJxhVcNq5QcQ559292	rogid:Qa3bMpzyvRxrvDq9dZUSQlfbpeg9606	intact-crc:CAFF348C8710EBA0|rigid:1S3ndMY8ZrXubpp6jreEYD5mcK0	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P25299	uniprotkb:Q7Z3B4	intact:EBI-15640|uniprotkb:D6VU95|ensemblfungi:YGL044C	intact:EBI-741048|uniprotkb:Q96EA7|uniprotkb:Q9NVL5|uniprotkb:Q9P0I1|uniprotkb:B2RCK7|intact:EBI-10966427|uniprotkb:B4DT35|ensembl:ENSP00000264883	psi-mi:rna15_yeast(display_long)|uniprotkb:YGL044C(locus name)|uniprotkb:RNA15(gene name)|psi-mi:RNA15(display_short)	psi-mi:nup54_human(display_long)|uniprotkb:54 kDa nucleoporin(gene name synonym)|uniprotkb:NUP54(gene name)|psi-mi:NUP54(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552176|imex:IM-24995-3615	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011471.1|sgd:S000003012|ensemblfungi:YGL044C(gene)|ensemblfungi:YGL044C_mRNA(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0005849"(mRNA cleavage factor complex)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0072423"(response to DNA damage checkpoint signaling)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR026896|interpro:IPR035979|interpro:IPR038192|rcsb pdb:2KM8|rcsb pdb:2L9B|rcsb pdb:2X1A|rcsb pdb:2X1B|rcsb pdb:2X1F|dip:DIP-1489N|mint:P25299	refseq:NP_059122.2|refseq:NP_001265532.1|ensembl:ENSG00000138750(gene)|ensembl:ENST00000264883(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0006605"(protein targeting)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036228"(protein localization to nuclear inner membrane)|go:"GO:0042306"(regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051028"(mRNA transport)|interpro:IPR024864|interpro:IPR025712|interpro:IPR040985|mint:Q7Z3B4|rcsb pdb:4JNU|rcsb pdb:4JNV|rcsb pdb:4JO7|rcsb pdb:4JO9|rcsb pdb:5IJN|rcsb pdb:5IJO|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933	-	crc64:10053B8648A71ECB	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:TqfxsTHAh9CPJJ6Q7uH6kz988hk559292	rogid:/X2b8J20uRh86bEeCc1tJSRuaIM9606	intact-crc:3AC7DFF8047F84D0|rigid:DPrDjqDiTFRoLirTjKgYNRaYX3Q	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P32505	uniprotkb:Q86SE5-3	intact:EBI-11770|ensemblfungi:YGL122C|uniprotkb:D6VU26	intact:EBI-11526555|ensembl:ENSP00000430128	psi-mi:nab2_yeast(display_long)|uniprotkb:YGL122C(locus name)|uniprotkb:NAB2(gene name)|psi-mi:NAB2(display_short)	psi-mi:q86se5-3(display_long)|uniprotkb:RALYL(gene name)|psi-mi:RALYL(display_short)|uniprotkb:HNRPCL3(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein C-like 3(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552180|imex:IM-24995-3616	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YGL122C(gene)|ensemblfungi:YGL122C_mRNA(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0008097"(5S rRNA binding)|go:"GO:0008143"("poly(A) binding")|go:"GO:0008312"(7S RNA binding)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0033204"(ribonuclease P RNA binding)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0046872"(metal ion binding)|go:"GO:1900152"(negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|interpro:IPR021083|interpro:IPR040366|go:"GO:0045945"(positive regulation of transcription by RNA polymerase III)|interpro:IPR041044|interpro:IPR043094|rcsb pdb:2JPS|rcsb pdb:2LHN|rcsb pdb:2V75|rcsb pdb:3LCN|rcsb pdb:3ZJ1|rcsb pdb:3ZJ2|rcsb pdb:4JLQ|rcsb pdb:5L2L|refseq:NP_011393.3|sgd:S000003090|mint:P32505|dip:DIP-1331N	ensembl:ENSG00000184672(gene)|ensembl:ENST00000517638(transcript)|intact:EBI-741520(isoform-parent)|uniprotkb:Q86SE5-3(isoform-parent)	-	crc64:40335C3D4658DD91	isoform-comment:No experimental confirmation available.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:tNdhCVVTRYjqg7BES5wD2Gg4rjw559292	rogid:7Vx29NJ3c8JBc76fGQWhrrQ9Stg9606	intact-crc:B7E7C67FD1CA9B9D|rigid:qh+Ucdp9I+wW4n5ydm5yk/WsF0c	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q86UW9	uniprotkb:Q06389	intact:EBI-740376|uniprotkb:Q96H69|uniprotkb:Q9H890|uniprotkb:Q9P200|uniprotkb:Q6XM88|ensembl:ENSP00000322885|ensembl:ENSP00000390218|ensembl:ENSP00000411986|uniprotkb:Q6XM87|intact:EBI-10192429|uniprotkb:Q4ZH49	intact:EBI-11946|ensemblfungi:YDR373W|uniprotkb:D6VT04	psi-mi:dtx2_human(display_long)|uniprotkb:RING finger protein 58(gene name synonym)|uniprotkb:DTX2(gene name)|psi-mi:DTX2(display_short)|uniprotkb:KIAA1528(gene name synonym)|uniprotkb:RNF58(gene name synonym)|uniprotkb:Protein deltex-2(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase DTX2(gene name synonym)	psi-mi:ncs1_yeast(display_long)|uniprotkb:FRQ1(gene name)|psi-mi:FRQ1(display_short)|uniprotkb:NCS1(gene name synonym)|uniprotkb:YDR373W(locus name)|uniprotkb:D9481.6(orf name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552184|imex:IM-24995-3617	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001096064.1|refseq:NP_001096065.1|refseq:NP_001096066.1|refseq:NP_065943.2|ensembl:ENSP00000322885|ensembl:ENSP00000390218|ensembl:ENSP00000411986|ensembl:ENST00000446820|ensembl:ENSP00000392545|ensembl:ENSG00000091073(gene)|ensembl:ENST00000324432(transcript)|ensembl:ENST00000413936(transcript)|ensembl:ENST00000430490(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031965"(nuclear membrane)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR004170(WWE)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR018123|interpro:IPR018957|interpro:IPR037197|interpro:IPR039396|interpro:IPR039398|interpro:IPR039399|mint:Q86UW9|rcsb pdb:6IR0|rcsb pdb:6Y22|rcsb pdb:6Y2X|rcsb pdb:6Y3J|reactome:R-HSA-2122948|refseq:XP_011514074.1|refseq:XP_011514075.1|refseq:XP_011514076.1|refseq:XP_011514077.1|refseq:XP_005250188.1|refseq:XP_005250189.1|refseq:XP_016867212.1|refseq:XP_016867213.1|refseq:XP_016867214.1|refseq:XP_016867215.1|refseq:XP_016867216.1	ensemblfungi:YDR373W(gene)|ensemblfungi:YDR373W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0033101"(cellular bud membrane)|go:"GO:0043128"(positive regulation of 1-phosphatidylinositol 4-kinase activity)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR028846|rcsb pdb:1FPW|rcsb pdb:2JU0|reactome:R-SCE-2514859|refseq:NP_010661.3|sgd:S000002781|mint:Q06389|dip:DIP-2733N	-	-	crc64:5E9D7F48F8AADA21	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:ugnjqAbG6Ekyc8MGugCnjc9zVaI9606	rogid:8mxxTP8CHNx24fQcjCxgDE7xhbs559292	intact-crc:9076AF27DB53C057|rigid:3wWYrx4hFjPIVMUN/p7zZOP9Wqg	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P38744	uniprotkb:Q7L190	intact:EBI-13396|uniprotkb:D3DKR5|ensemblfungi:YHL018W	intact:EBI-710457|intact:EBI-28975079|ensembl:ENSP00000335306|uniprotkb:Q9H9N5|uniprotkb:Q9NVI6|uniprotkb:A8K4M7	psi-mi:phs_yeast(display_long)|uniprotkb:4-alpha-hydroxy-tetrahydropterin dehydratase(gene name synonym)|uniprotkb:Pterin carbinolamine dehydratase(gene name synonym)|uniprotkb:YHL018W(locus name)	psi-mi:dppa4_human(display_long)|uniprotkb:DPPA4(gene name)|psi-mi:DPPA4(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552164|imex:IM-24995-3612	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011845.1|sgd:S000001010|interpro:IPR036428|interpro:IPR001533(Transcriptional coactivator/pterin dehydratase)|ensemblfungi:YHL018W(gene)|ensemblfungi:YHL018W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0008124"(4-alpha-hydroxytetrahydrobiopterin dehydratase activity)|dip:DIP-1872N|reactome:R-SCE-8964208	refseq:NP_060659.3|mint:Q7L190|reactome:R-HSA-2892247|ensembl:ENSG00000121570(gene)|ensembl:ENST00000335658(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0048731"(system development)|go:"GO:0060484"(lung-associated mesenchyme development)|interpro:IPR025891|interpro:IPR025892|interpro:IPR039590|interpro:IPR039836|ensembl:ENSP00000335306	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:7+JuLX1wFw/tkE4NcSCTK62b4DU559292	rogid:WKqQ0ipAAfKsDRuXJhtTWJcROdc9606	intact-crc:967BD4F45CD21E28|rigid:v9KswGtAu+XifBD3ie3kecZgK+w	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P25372	uniprotkb:Q8IUQ4-2	intact:EBI-19616|uniprotkb:D6VR84|ensemblfungi:YCR083W	intact:EBI-11522811|ensembl:ENSP00000349156	psi-mi:trx3_yeast(display_long)|uniprotkb:TRX3(gene name)|psi-mi:TRX3(display_short)|uniprotkb:YCR83W(orf name)|uniprotkb:YCR083W(locus name)	psi-mi:q8iuq4-2(display_long)|uniprotkb:SIAH1(gene name)|psi-mi:SIAH1(display_short)|uniprotkb:HUMSIAH(gene name synonym)|uniprotkb:Seven in absentia homolog 1(gene name synonym)|uniprotkb:Siah-1a(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase SIAH1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552228|imex:IM-24995-3628	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR036249|refseq:NP_010006.1|sgd:S000000679|interpro:IPR017937|interpro:IPR013766(Thioredoxin domain)|rcsb pdb:2OE0|rcsb pdb:2OE1|rcsb pdb:2OE3|ensemblfungi:YCR083W(gene)|ensemblfungi:YCR083W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0015036"(disulfide oxidoreductase activity)|go:"GO:0034599"(cellular response to oxidative stress)|rcsb pdb:5YKW	intact:EBI-747107(isoform-parent)|ensembl:ENSG00000196470(gene)|ensembl:ENST00000356721(transcript)|uniprotkb:Q8IUQ4-2(isoform-parent)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:g0xjGf9GvJRl8iv2qoT5tOs7jXI559292	rogid:M4q06jVbWuq1mGMXvtuFBaMEgZM9606	intact-crc:047EE57C2982BC2F|rigid:ag+O9md4JZaSgB2+97fHyAL1Ft8	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q86UW9	uniprotkb:P38340	intact:EBI-740376|uniprotkb:Q96H69|uniprotkb:Q9H890|uniprotkb:Q9P200|uniprotkb:Q6XM88|ensembl:ENSP00000322885|ensembl:ENSP00000390218|ensembl:ENSP00000411986|uniprotkb:Q6XM87|intact:EBI-10192429|uniprotkb:Q4ZH49	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:dtx2_human(display_long)|uniprotkb:RING finger protein 58(gene name synonym)|uniprotkb:DTX2(gene name)|psi-mi:DTX2(display_short)|uniprotkb:KIAA1528(gene name synonym)|uniprotkb:RNF58(gene name synonym)|uniprotkb:Protein deltex-2(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase DTX2(gene name synonym)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552188|imex:IM-24995-3618	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001096064.1|refseq:NP_001096065.1|refseq:NP_001096066.1|refseq:NP_065943.2|ensembl:ENSP00000322885|ensembl:ENSP00000390218|ensembl:ENSP00000411986|ensembl:ENST00000446820|ensembl:ENSP00000392545|ensembl:ENSG00000091073(gene)|ensembl:ENST00000324432(transcript)|ensembl:ENST00000413936(transcript)|ensembl:ENST00000430490(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031965"(nuclear membrane)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR004170(WWE)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR018123|interpro:IPR018957|interpro:IPR037197|interpro:IPR039396|interpro:IPR039398|interpro:IPR039399|mint:Q86UW9|rcsb pdb:6IR0|rcsb pdb:6Y22|rcsb pdb:6Y2X|rcsb pdb:6Y3J|reactome:R-HSA-2122948|refseq:XP_011514074.1|refseq:XP_011514075.1|refseq:XP_011514076.1|refseq:XP_011514077.1|refseq:XP_005250188.1|refseq:XP_005250189.1|refseq:XP_016867212.1|refseq:XP_016867213.1|refseq:XP_016867214.1|refseq:XP_016867215.1|refseq:XP_016867216.1	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F	-	-	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:ugnjqAbG6Ekyc8MGugCnjc9zVaI9606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:3C26119FCD88FE40|rigid:1Ha/wQdxNX3u33uinTzJuwTQHR4	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q86UW9	uniprotkb:P32477	intact:EBI-740376|uniprotkb:Q96H69|uniprotkb:Q9H890|uniprotkb:Q9P200|uniprotkb:Q6XM88|ensembl:ENSP00000322885|ensembl:ENSP00000390218|ensembl:ENSP00000411986|uniprotkb:Q6XM87|intact:EBI-10192429|uniprotkb:Q4ZH49	intact:EBI-7910|uniprotkb:D6VW83|ensemblfungi:YJL101C	psi-mi:dtx2_human(display_long)|uniprotkb:RING finger protein 58(gene name synonym)|uniprotkb:DTX2(gene name)|psi-mi:DTX2(display_short)|uniprotkb:KIAA1528(gene name synonym)|uniprotkb:RNF58(gene name synonym)|uniprotkb:Protein deltex-2(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase DTX2(gene name synonym)	psi-mi:gsh1_yeast(display_long)|uniprotkb:GSH1(gene name)|psi-mi:GSH1(display_short)|uniprotkb:YJL101C(locus name)|uniprotkb:J0832(orf name)|uniprotkb:Gamma-glutamylcysteine synthetase(gene name synonym)|uniprotkb:Gamma-ECS(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552192|imex:IM-24995-3619	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001096064.1|refseq:NP_001096065.1|refseq:NP_001096066.1|refseq:NP_065943.2|ensembl:ENSP00000322885|ensembl:ENSP00000390218|ensembl:ENSP00000411986|ensembl:ENST00000446820|ensembl:ENSP00000392545|ensembl:ENSG00000091073(gene)|ensembl:ENST00000324432(transcript)|ensembl:ENST00000413936(transcript)|ensembl:ENST00000430490(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031965"(nuclear membrane)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR004170(WWE)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR018123|interpro:IPR018957|interpro:IPR037197|interpro:IPR039396|interpro:IPR039398|interpro:IPR039399|mint:Q86UW9|rcsb pdb:6IR0|rcsb pdb:6Y22|rcsb pdb:6Y2X|rcsb pdb:6Y3J|reactome:R-HSA-2122948|refseq:XP_011514074.1|refseq:XP_011514075.1|refseq:XP_011514076.1|refseq:XP_011514077.1|refseq:XP_005250188.1|refseq:XP_005250189.1|refseq:XP_016867212.1|refseq:XP_016867213.1|refseq:XP_016867214.1|refseq:XP_016867215.1|refseq:XP_016867216.1	refseq:NP_012434.1|sgd:S000003637|interpro:IPR004308(Glutamate-cysteine ligase catalytic subunit)|rcsb pdb:3IG5|rcsb pdb:3IG8|rcsb pdb:3LVV|rcsb pdb:3LVW|interpro:IPR014746(Glutamine synthetase/guanido kinase, catalytic region)|ensemblfungi:YJL101C(gene)|ensemblfungi:YJL101C_mRNA(transcript)|go:"GO:0004357"(glutamate-cysteine ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006750"(glutathione biosynthetic process)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0046686"(response to cadmium ion)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:ugnjqAbG6Ekyc8MGugCnjc9zVaI9606	rogid:83EkWwY4UUf7Rvoxtj6HiUr/uHE559292	intact-crc:297CD7C2885A6D88|rigid:Tf2s0BnZ1YD0Jp6k+Nk+tDfHNzM	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q86V42-3	uniprotkb:P13186	intact:EBI-11523323|ensembl:ENSP00000481212	intact:EBI-9723|uniprotkb:Q12384|ensemblfungi:YLR096W|uniprotkb:D6VY96	psi-mi:q86v42-3(display_long)|uniprotkb:FAM124A(gene name)|psi-mi:FAM124A(display_short)	psi-mi:kin2_yeast(display_long)|uniprotkb:L8004.3(orf name)|uniprotkb:YLR096W(locus name)|uniprotkb:KIN2(gene name)|psi-mi:KIN2(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552196|imex:IM-24995-3620	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000150510(gene)|ensembl:ENST00000615498(transcript)|intact:EBI-744506(isoform-parent)	go:"GO:0005935"(cellular bud neck)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006887"(exocytosis)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0045921"(positive regulation of exocytosis)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903896"(positive regulation of IRE1-mediated unfolded protein response)|interpro:IPR000719(Protein kinase, core)|ensemblfungi:YLR096W(gene)|ensemblfungi:YLR096W_mRNA(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005934"(cellular bud tip)|interpro:IPR001772(Kinase-associated KA1)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR028375|reactome:R-SCE-1632852|reactome:R-SCE-380972|refseq:NP_013197.1|sgd:S000004086|dip:DIP-6276N|mint:P13186	-	-	crc64:AC2660BF3CA69600	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:tWx14HsCfMtI8yIrYJCt8V4lr+c9606	rogid:OkRLTXiGL1oYkrvvB/KznlaEvrE559292	intact-crc:DB6556B479BE19D2|rigid:col8/KUv7mr3nLS9KHMq/YIXCnM	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q86WT6-2	uniprotkb:P38340	intact:EBI-11525489|ensembl:ENSP00000342922|ensembl:ENSP00000479720	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:q86wt6-2(display_long)|uniprotkb:RING-type E3 ubiquitin transferase TRIM69(gene name synonym)|uniprotkb:TRIM69(gene name)|psi-mi:TRIM69(display_short)|uniprotkb:RFP-like domain-containing protein trimless(gene name synonym)|uniprotkb:RING finger protein 36(gene name synonym)|uniprotkb:RNF36(gene name synonym)|uniprotkb:Tripartite motif-containing protein 69(gene name synonym)|uniprotkb:HSD-34(orf name)|uniprotkb:HSD34(orf name)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552200|imex:IM-24995-3621	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-749955(isoform-parent)|uniprotkb:Q86WT6-2(isoform-parent)|ensembl:ENSG00000185880(gene)|ensembl:ENSG00000278211(gene)|ensembl:ENST00000338264(transcript)|ensembl:ENST00000618398(transcript)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F	-	-	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:J0mzn4PSX5vWZqt4X3Ee1Wxx5hw9606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:E380E4C4D07B93EF|rigid:rYUx2nVbzRHViiZnnNUPEFxMCpA	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q86WT6-2	uniprotkb:P32464	intact:EBI-11525489|ensembl:ENSP00000342922|ensembl:ENSP00000479720	intact:EBI-8859|ensemblfungi:YKL189W|uniprotkb:D6VX11	psi-mi:q86wt6-2(display_long)|uniprotkb:RING-type E3 ubiquitin transferase TRIM69(gene name synonym)|uniprotkb:TRIM69(gene name)|psi-mi:TRIM69(display_short)|uniprotkb:RFP-like domain-containing protein trimless(gene name synonym)|uniprotkb:RING finger protein 36(gene name synonym)|uniprotkb:RNF36(gene name synonym)|uniprotkb:Tripartite motif-containing protein 69(gene name synonym)|uniprotkb:HSD-34(orf name)|uniprotkb:HSD34(orf name)	psi-mi:hym1_yeast(display_long)|uniprotkb:YKL189W(locus name)|uniprotkb:HYM1(gene name)|psi-mi:HYM1(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552204|imex:IM-24995-3622	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-749955(isoform-parent)|uniprotkb:Q86WT6-2(isoform-parent)|ensembl:ENSG00000185880(gene)|ensembl:ENSG00000278211(gene)|ensembl:ENST00000338264(transcript)|ensembl:ENST00000618398(transcript)	ensemblfungi:YKL189W(gene)|ensemblfungi:YKL189W_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0000920"(septum digestion after cytokinesis)|go:"GO:0005933"(cellular bud)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007118"(budding cell apical bud growth)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043332"(mating projection tip)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0044732"(mitotic spindle pole body)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013878(Mo25-like)|interpro:IPR016024(Armadillo-type fold)|reactome:R-SCE-6798695|refseq:NP_012732.1|sgd:S000001672|mint:P32464|dip:DIP-5425N	-	-	crc64:F48860754C892BA9	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:J0mzn4PSX5vWZqt4X3Ee1Wxx5hw9606	rogid:pOlQFFuYgFzmqf3ZGUVkBj9h7Uc559292	intact-crc:FB5F7197543AA5E9|rigid:iy9StxYBZ2cOGdyRWb1zM+gLOQA	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P32502	uniprotkb:Q86WT6-2	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	intact:EBI-11525489|ensembl:ENSP00000342922|ensembl:ENSP00000479720	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:q86wt6-2(display_long)|uniprotkb:RING-type E3 ubiquitin transferase TRIM69(gene name synonym)|uniprotkb:TRIM69(gene name)|psi-mi:TRIM69(display_short)|uniprotkb:RFP-like domain-containing protein trimless(gene name synonym)|uniprotkb:RING finger protein 36(gene name synonym)|uniprotkb:RNF36(gene name synonym)|uniprotkb:Tripartite motif-containing protein 69(gene name synonym)|uniprotkb:HSD-34(orf name)|uniprotkb:HSD34(orf name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552208|imex:IM-24995-3623	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731	intact:EBI-749955(isoform-parent)|uniprotkb:Q86WT6-2(isoform-parent)|ensembl:ENSG00000185880(gene)|ensembl:ENSG00000278211(gene)|ensembl:ENST00000338264(transcript)|ensembl:ENST00000618398(transcript)	-	crc64:A5409FAF1594854C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	rogid:J0mzn4PSX5vWZqt4X3Ee1Wxx5hw9606	intact-crc:648CB165209DB1BE|rigid:LgqfhMLw94zWouczTI/WdTVZE4c	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P38340	uniprotkb:Q8IUQ4-2	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-11522811|ensembl:ENSP00000349156	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:q8iuq4-2(display_long)|uniprotkb:SIAH1(gene name)|psi-mi:SIAH1(display_short)|uniprotkb:HUMSIAH(gene name synonym)|uniprotkb:Seven in absentia homolog 1(gene name synonym)|uniprotkb:Siah-1a(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase SIAH1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552212|imex:IM-24995-3624	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F	intact:EBI-747107(isoform-parent)|ensembl:ENSG00000196470(gene)|ensembl:ENST00000356721(transcript)|uniprotkb:Q8IUQ4-2(isoform-parent)	-	crc64:66699F37B0013088	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:M4q06jVbWuq1mGMXvtuFBaMEgZM9606	intact-crc:5F1CBCEF8246DD0F|rigid:0el1JYLTyDSSh/VBenuQxdsjgiE	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P01097	uniprotkb:Q8IUQ4-2	intact:EBI-8874|ensemblfungi:YDL181W|uniprotkb:D6VRH1	intact:EBI-11522811|ensembl:ENSP00000349156	psi-mi:atif_yeast(display_long)|uniprotkb:INH1(gene name)|psi-mi:INH1(display_short)|uniprotkb:ATP synthase F1 subunit epsilon(gene name synonym)|uniprotkb:D1305(orf name)|uniprotkb:YDL181W(locus name)	psi-mi:q8iuq4-2(display_long)|uniprotkb:SIAH1(gene name)|psi-mi:SIAH1(display_short)|uniprotkb:HUMSIAH(gene name synonym)|uniprotkb:Seven in absentia homolog 1(gene name synonym)|uniprotkb:Siah-1a(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase SIAH1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552216|imex:IM-24995-3625	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YDL181W(gene)|ensemblfungi:YDL181W_mRNA(transcript)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0042030"(ATPase inhibitor activity)|interpro:IPR007648(Mitochondrial ATPase inhibitor, IATP)|rcsb pdb:3ZIA|refseq:NP_010100.1|sgd:S000002340|mint:P01097|dip:DIP-2985N	intact:EBI-747107(isoform-parent)|ensembl:ENSG00000196470(gene)|ensembl:ENST00000356721(transcript)|uniprotkb:Q8IUQ4-2(isoform-parent)	-	crc64:E1AF73A47F63CE58	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:3wsu4TOLAZdm97Kfhla8l4UKFEk559292	rogid:M4q06jVbWuq1mGMXvtuFBaMEgZM9606	intact-crc:16C1582C76F1B4CD|rigid:lxgj5yAVRLdMImSQ2jj9qkoEhcI	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8IUQ4-2	uniprotkb:P32502	intact:EBI-11522811|ensembl:ENSP00000349156	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:q8iuq4-2(display_long)|uniprotkb:SIAH1(gene name)|psi-mi:SIAH1(display_short)|uniprotkb:HUMSIAH(gene name synonym)|uniprotkb:Seven in absentia homolog 1(gene name synonym)|uniprotkb:Siah-1a(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase SIAH1(gene name synonym)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552220|imex:IM-24995-3626	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-747107(isoform-parent)|ensembl:ENSG00000196470(gene)|ensembl:ENST00000356721(transcript)|uniprotkb:Q8IUQ4-2(isoform-parent)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731	-	-	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:M4q06jVbWuq1mGMXvtuFBaMEgZM9606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:3DBBB13DFADC4494|rigid:Jfgb2nu4MWuYBnqsnt63a0IKQZw	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8IUQ4-2	uniprotkb:P39518	intact:EBI-11522811|ensembl:ENSP00000349156	intact:EBI-10082|uniprotkb:D3DLR3|ensemblfungi:YER015W	psi-mi:q8iuq4-2(display_long)|uniprotkb:SIAH1(gene name)|psi-mi:SIAH1(display_short)|uniprotkb:HUMSIAH(gene name synonym)|uniprotkb:Seven in absentia homolog 1(gene name synonym)|uniprotkb:Siah-1a(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase SIAH1(gene name synonym)	psi-mi:lcf2_yeast(display_long)|uniprotkb:YER015W(locus name)|uniprotkb:FAA2(gene name)|psi-mi:FAA2(display_short)|uniprotkb:FAM1(gene name synonym)|uniprotkb:Long-chain acyl-CoA synthetase 2(gene name synonym)|uniprotkb:Fatty acid activator 2(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552224|imex:IM-24995-3627	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-747107(isoform-parent)|ensembl:ENSG00000196470(gene)|ensembl:ENST00000356721(transcript)|uniprotkb:Q8IUQ4-2(isoform-parent)	sgd:S000000817|ensemblfungi:YER015W_mRNA(transcript)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0004467"(long-chain fatty acid-CoA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0015910"(long-chain fatty acid import into peroxisome)|go:"GO:0015916"(fatty-acyl-CoA transport)|go:"GO:0016020"(membrane)|go:"GO:0031956"(medium-chain fatty acid-CoA ligase activity)|go:"GO:0031957"(very long-chain fatty acid-CoA ligase activity)|go:"GO:0042760"(very long-chain fatty acid catabolic process)|go:"GO:0102391"(decanoate-CoA ligase activity)|ensemblfungi:YER015W(gene)|interpro:IPR020845|interpro:IPR000873(AMP-dependent synthetase and ligase)|reactome:R-SCE-75876|refseq:NP_010931.3|dip:DIP-6565N	-	-	crc64:1E023C18682805BC	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:M4q06jVbWuq1mGMXvtuFBaMEgZM9606	rogid:N0W+wPvCsl01y0k8hJZ156LztOo559292	intact-crc:3251D693C66FC2B8|rigid:QY3qRKX+Ly4iEvVnVLbkyovBdqQ	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8IYA8	uniprotkb:Q12329	intact:EBI-8638439|intact:EBI-28969497|ensembl:ENSP00000296449|ensembl:ENSP00000391788|ensembl:ENSP00000407837|uniprotkb:C9JJL0|uniprotkb:Q96LP7|intact:MINT-8162095|uniprotkb:Q05DG9	intact:EBI-8571|uniprotkb:D6VSF3|ensemblfungi:YDR171W	psi-mi:iho1_human(display_long)|uniprotkb:IHO1(gene name)|psi-mi:IHO1(display_short)|uniprotkb:CCDC36(gene name synonym)|uniprotkb:Cancer/testis antigen 74(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 36(gene name synonym)	psi-mi:hsp42_yeast(display_long)|uniprotkb:HSP42(gene name)|psi-mi:HSP42(display_short)|uniprotkb:YDR171W(locus name)|uniprotkb:YD9395.04(orf name)|uniprotkb:42 kDa heat shock protein(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552260|imex:IM-24995-3636	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000296449|ensembl:ENST00000366429|ensembl:ENSP00000403700|ensembl:ENSP00000391788|ensembl:ENSP00000407837|ensembl:ENSG00000173421(gene)|ensembl:ENST00000296449(transcript)|ensembl:ENST00000438782(transcript)|ensembl:ENST00000452691(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0006310"(DNA recombination)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0042138"(meiotic DNA double-strand break formation)|go:"GO:0048477"(oogenesis)|go:"GO:0060629"(regulation of homologous chromosome segregation)|interpro:IPR031529|mint:Q8IYA8|refseq:XP_011531974.1|refseq:XP_011531975.1|refseq:NP_001128669.1|refseq:NP_835467.2|refseq:XP_006713187.1	refseq:NP_010456.1|sgd:S000002578|mint:Q12329|dip:DIP-2515N|ensemblfungi:YDR171W(gene)|ensemblfungi:YDR171W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0009408"(response to heat)|go:"GO:0009651"(response to salt stress)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043621"(protein self-association)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0140311"(protein sequestering activity)|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR031107	-	comment:mint	crc64:DF353A76493E3CE6	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:+TNQLExkhmC1NWqsE240Cx7zFVU9606	rogid:izvrv04fA3zcBqTeUeHD/erKGf4559292	intact-crc:BBFB17CC0EF6BE1D|rigid:e2BgtnOteZXZbtFm3URi4h2shDM	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8IYA8	uniprotkb:Q04307	intact:EBI-8638439|intact:EBI-28969497|ensembl:ENSP00000296449|ensembl:ENSP00000391788|ensembl:ENSP00000407837|uniprotkb:C9JJL0|uniprotkb:Q96LP7|intact:MINT-8162095|uniprotkb:Q05DG9	intact:EBI-15858|uniprotkb:Q2VQW5|ensemblfungi:YDR045C|uniprotkb:D6VS33	psi-mi:iho1_human(display_long)|uniprotkb:IHO1(gene name)|psi-mi:IHO1(display_short)|uniprotkb:CCDC36(gene name synonym)|uniprotkb:Cancer/testis antigen 74(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 36(gene name synonym)	psi-mi:rpc10_yeast(display_long)|uniprotkb:RPC11(gene name)|psi-mi:RPC11(display_short)|uniprotkb:YDR045C(locus name)|uniprotkb:YD9609.01C(orf name)|uniprotkb:RNA polymerase III subunit C11(gene name synonym)|uniprotkb:DNA-directed RNA polymerases III 12.5 kDa polypeptide(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552248|imex:IM-24995-3633	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000296449|ensembl:ENST00000366429|ensembl:ENSP00000403700|ensembl:ENSP00000391788|ensembl:ENSP00000407837|ensembl:ENSG00000173421(gene)|ensembl:ENST00000296449(transcript)|ensembl:ENST00000438782(transcript)|ensembl:ENST00000452691(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0006310"(DNA recombination)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0042138"(meiotic DNA double-strand break formation)|go:"GO:0048477"(oogenesis)|go:"GO:0060629"(regulation of homologous chromosome segregation)|interpro:IPR031529|mint:Q8IYA8|refseq:XP_011531974.1|refseq:XP_011531975.1|refseq:NP_001128669.1|refseq:NP_835467.2|refseq:XP_006713187.1	ensemblfungi:YDR045C(gene)|refseq:NP_010330.1|sgd:S000002452|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006386"(termination of RNA polymerase III transcription)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042779"(tRNA 3'-trailer cleavage)|go:"GO:0042797"(tRNA transcription by RNA polymerase III)|interpro:IPR001222(Zinc finger, TFIIS-type)|interpro:IPR001529(DNA-directed RNA polymerase, M/15 kDa subunit)|interpro:IPR012164(DNA-directed RNA polymerase, subunit C11/M/9)|interpro:IPR019761|interpro:IPR034014|rcsb pdb:3QT1|ensemblfungi:YDR045C_mRNA(transcript)|rcsb pdb:5FJ8|rcsb pdb:5FJ9|rcsb pdb:5FJA|rcsb pdb:6CNB|rcsb pdb:6CNC|rcsb pdb:6CND|rcsb pdb:6CNF|rcsb pdb:6EU0|rcsb pdb:6EU2|rcsb pdb:6EU3|rcsb pdb:6F40|rcsb pdb:6F41|rcsb pdb:6F42|rcsb pdb:6F44|rcsb pdb:6TUT|reactome:R-SCE-76061|reactome:R-SCE-76066|rcsb pdb:6EU1|dip:DIP-887N|mint:Q04307	-	comment:mint	crc64:E4AA802EC9F92230	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:+TNQLExkhmC1NWqsE240Cx7zFVU9606	rogid:G2fIQbptabHIUI224iPtTJF+dIs559292	intact-crc:A77997858C3F89D2|rigid:LjCxaMqrV6DJwAVZcb9AK1ol74s	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8IYA8	uniprotkb:P53286	intact:EBI-8638439|intact:EBI-28969497|ensembl:ENSP00000296449|ensembl:ENSP00000391788|ensembl:ENSP00000407837|uniprotkb:C9JJL0|uniprotkb:Q96LP7|intact:MINT-8162095|uniprotkb:Q05DG9	intact:EBI-3796|uniprotkb:D6VUS2|ensemblfungi:YGR142W	psi-mi:iho1_human(display_long)|uniprotkb:IHO1(gene name)|psi-mi:IHO1(display_short)|uniprotkb:CCDC36(gene name synonym)|uniprotkb:Cancer/testis antigen 74(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 36(gene name synonym)	psi-mi:btn2_yeast(display_long)|uniprotkb:YGR142W(locus name)|uniprotkb:BTN2(gene name)|psi-mi:BTN2(display_short)|uniprotkb:Batten disease protein 2(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552256|imex:IM-24995-3635	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000296449|ensembl:ENST00000366429|ensembl:ENSP00000403700|ensembl:ENSP00000391788|ensembl:ENSP00000407837|ensembl:ENSG00000173421(gene)|ensembl:ENST00000296449(transcript)|ensembl:ENST00000438782(transcript)|ensembl:ENST00000452691(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0006310"(DNA recombination)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0042138"(meiotic DNA double-strand break formation)|go:"GO:0048477"(oogenesis)|go:"GO:0060629"(regulation of homologous chromosome segregation)|interpro:IPR031529|mint:Q8IYA8|refseq:XP_011531974.1|refseq:XP_011531975.1|refseq:NP_001128669.1|refseq:NP_835467.2|refseq:XP_006713187.1	sgd:S000003374|refseq:NP_011658.3|dip:DIP-5534N|mint:P53286|ensemblfungi:YGR142W(gene)|ensemblfungi:YGR142W_mRNA(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005634"(nucleus)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006865"(amino acid transport)|go:"GO:0006885"(regulation of pH)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051087"(chaperone binding)|go:"GO:0140311"(protein sequestering activity)	-	comment:mint	crc64:E7AE1EB1E3612F3E	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:+TNQLExkhmC1NWqsE240Cx7zFVU9606	rogid:Cu27xkwGMNyS4zLvUaG1UeH2mE0559292	intact-crc:A266D5E5D07B1FA9|rigid:/wTZoa7rX6rntZfQHb0One7J6Ew	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8IYA8	uniprotkb:Q02647	intact:EBI-8638439|intact:EBI-28969497|ensembl:ENSP00000296449|ensembl:ENSP00000391788|ensembl:ENSP00000407837|uniprotkb:C9JJL0|uniprotkb:Q96LP7|intact:MINT-8162095|uniprotkb:Q05DG9	intact:EBI-6240|uniprotkb:D6VT54|ensemblfungi:YDR424C	psi-mi:iho1_human(display_long)|uniprotkb:IHO1(gene name)|psi-mi:IHO1(display_short)|uniprotkb:CCDC36(gene name synonym)|uniprotkb:Cancer/testis antigen 74(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 36(gene name synonym)	psi-mi:dyl1_yeast(display_long)|uniprotkb:DYN2(gene name)|psi-mi:DYN2(display_short)|uniprotkb:SLC1(gene name synonym)|uniprotkb:YDR424C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552252|imex:IM-24995-3634	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000296449|ensembl:ENST00000366429|ensembl:ENSP00000403700|ensembl:ENSP00000391788|ensembl:ENSP00000407837|ensembl:ENSG00000173421(gene)|ensembl:ENST00000296449(transcript)|ensembl:ENST00000438782(transcript)|ensembl:ENST00000452691(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0006310"(DNA recombination)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0042138"(meiotic DNA double-strand break formation)|go:"GO:0048477"(oogenesis)|go:"GO:0060629"(regulation of homologous chromosome segregation)|interpro:IPR031529|mint:Q8IYA8|refseq:XP_011531974.1|refseq:XP_011531975.1|refseq:NP_001128669.1|refseq:NP_835467.2|refseq:XP_006713187.1	refseq:NP_010712.1|sgd:S000002832|dip:DIP-6480N|mint:Q02647|interpro:IPR001372(Dynein light chain, type 1 and 2)|interpro:IPR019763|interpro:IPR037177|rcsb pdb:4DS1|rcsb pdb:4HT6|reactome:R-SCE-6798695|ensemblfungi:YDR424C(gene)|ensemblfungi:YDR424C_mRNA(transcript)|go:"GO:0005643"(nuclear pore)|go:"GO:0005868"(cytoplasmic dynein complex)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0015031"(protein transport)|go:"GO:0030286"(dynein complex)|go:"GO:0030473"(nuclear migration along microtubule)|go:"GO:0034399"(nuclear periphery)|go:"GO:0040001"(establishment of mitotic spindle localization)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0051028"(mRNA transport)|go:"GO:0051292"(nuclear pore complex assembly)|go:"GO:0051959"(dynein light intermediate chain binding)|go:"GO:1990429"(peroxisomal importomer complex)|go:"GO:2000582"(obsolete positive regulation of microtubule motor activity, plus-end-directed)	-	comment:mint	crc64:C25A690F35C3CEEC	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:+TNQLExkhmC1NWqsE240Cx7zFVU9606	rogid:VzzUwItKMyp/zI7n/iI7VK4QiEA559292	intact-crc:680E1660CA2114D6|rigid:gohT56T3Co0JinL5kHIziH3vKxc	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8IYA8	uniprotkb:Q12259	intact:EBI-8638439|intact:EBI-28969497|ensembl:ENSP00000296449|ensembl:ENSP00000391788|ensembl:ENSP00000407837|uniprotkb:C9JJL0|uniprotkb:Q96LP7|intact:MINT-8162095|uniprotkb:Q05DG9	intact:EBI-30776|uniprotkb:D6VYA8|ensemblfungi:YLR108C	psi-mi:iho1_human(display_long)|uniprotkb:IHO1(gene name)|psi-mi:IHO1(display_short)|uniprotkb:CCDC36(gene name synonym)|uniprotkb:Cancer/testis antigen 74(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 36(gene name synonym)	psi-mi:yl108_yeast(display_long)|uniprotkb:L2913(orf name)|uniprotkb:YLR108C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552264|imex:IM-24995-3637	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000296449|ensembl:ENST00000366429|ensembl:ENSP00000403700|ensembl:ENSP00000391788|ensembl:ENSP00000407837|ensembl:ENSG00000173421(gene)|ensembl:ENST00000296449(transcript)|ensembl:ENST00000438782(transcript)|ensembl:ENST00000452691(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0006310"(DNA recombination)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0042138"(meiotic DNA double-strand break formation)|go:"GO:0048477"(oogenesis)|go:"GO:0060629"(regulation of homologous chromosome segregation)|interpro:IPR031529|mint:Q8IYA8|refseq:XP_011531974.1|refseq:XP_011531975.1|refseq:NP_001128669.1|refseq:NP_835467.2|refseq:XP_006713187.1	refseq:NP_013209.1|sgd:S000004098|dip:DIP-4075N|ensemblfungi:YLR108C(gene)|ensemblfungi:YLR108C_mRNA(transcript)|go:"GO:0005634"(nucleus)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)	-	comment:mint	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:+TNQLExkhmC1NWqsE240Cx7zFVU9606	rogid:CzknxXhhvgMp3J0/oi197EgZ05U559292	intact-crc:4FB6ACF71F270182|rigid:cm1ZX5U6As/tFOEf2aR5MhHMFu0	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P38340	uniprotkb:Q8IXK0-5	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-11527347|ensembl:ENSP00000507877	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:q8ixk0-5(display_long)|uniprotkb:EDR2(gene name synonym)|uniprotkb:Early development regulatory protein 2(gene name synonym)|uniprotkb:PH2(gene name synonym)|uniprotkb:PHC2(gene name)|psi-mi:PHC2(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552240|imex:IM-24995-3631	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F	ensembl:ENSG00000134686(gene)|ensembl:ENST00000683057(transcript)|intact:EBI-713786(isoform-parent)|uniprotkb:Q8IXK0-5(isoform-parent)	-	crc64:66699F37B0013088	isoform-comment:No experimental confirmation available.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:bkZ10pedX8mCMrcppjyd4tl7hm09606	intact-crc:9E35B829411693B3|rigid:UK282+UTG2MbTh7PNk4WAupJt0w	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P38206	uniprotkb:Q8IV61	intact:EBI-15028|uniprotkb:Q05814|uniprotkb:D6VPY0|ensemblfungi:YBL020W	intact:EBI-1047876|uniprotkb:O94931|uniprotkb:Q53SD7|uniprotkb:D6W583|ensembl:ENSP00000384192|ensembl:ENSP00000385886	psi-mi:rft1_yeast(display_long)|uniprotkb:RFT1(gene name)|psi-mi:RFT1(display_short)|uniprotkb:YBL020W(locus name)|uniprotkb:YBL0442(orf name)|uniprotkb:Requiring fifty-three protein 1(gene name synonym)	psi-mi:grp3_human(display_long)|uniprotkb:Calcium and DAG-regulated guanine nucleotide exchange factor III(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor for Rap1(gene name synonym)|uniprotkb:RASGRP3(gene name)|psi-mi:RASGRP3(display_short)|uniprotkb:GRP3(gene name synonym)|uniprotkb:KIAA0846(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552236|imex:IM-24995-3630	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009533.1|sgd:S000000116|ensemblfungi:YBL020W(gene)|ensemblfungi:YBL020W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006488"(dolichol-linked oligosaccharide biosynthetic process)|go:"GO:0008643"(carbohydrate transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034202"(glycolipid floppase activity)|go:"GO:0034203"(glycolipid translocation)|interpro:IPR007594(RFT1)|dip:DIP-3885N|mint:P38206	refseq:NP_001132960.1|refseq:NP_056191.1|refseq:NP_733772.1|refseq:XP_011531048.1|refseq:XP_011531049.1|refseq:XP_016859248.1|refseq:XP_016859249.1|refseq:XP_016859250.1|refseq:XP_016859251.1|refseq:XP_016859252.1|refseq:XP_011531050.2|ensembl:ENSG00000152689(gene)|ensembl:ENST00000402538(transcript)|ensembl:ENST00000403687(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0019900"(kinase binding)|go:"GO:0019992"(diacylglycerol binding)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR000651(Guanine nucleotide exchange factor for Ras-like GTPases, N-terminal)|interpro:IPR001895(Guanine-nucleotide dissociation stimulator CDC25)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008937(Ras guanine nucleotide exchange factor)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR020454|interpro:IPR023578|interpro:IPR029645|interpro:IPR036964|reactome:R-HSA-1169092|reactome:R-HSA-5673001|refseq:XP_005264303.1	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:nBfsGoVh81NwPryblR48jOVVQsU559292	rogid:yO4CIzGZmGYS124YcNmFKQh7+bo9606	intact-crc:2EF855891C132B83|rigid:ni8QLeHB1RRrD7d0Bqy0qtRmISk	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P53243	uniprotkb:Q8IUQ4-2	intact:EBI-23197|uniprotkb:D6VUK1|ensemblfungi:YGR067C	intact:EBI-11522811|ensembl:ENSP00000349156	psi-mi:yg2a_yeast(display_long)|uniprotkb:YGR067C(locus name)	psi-mi:q8iuq4-2(display_long)|uniprotkb:SIAH1(gene name)|psi-mi:SIAH1(display_short)|uniprotkb:HUMSIAH(gene name synonym)|uniprotkb:Seven in absentia homolog 1(gene name synonym)|uniprotkb:Siah-1a(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase SIAH1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552232|imex:IM-24995-3629	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003299|refseq:NP_011581.4|dip:DIP-2819N|mint:P53243|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|ensemblfungi:YGR067C(gene)|ensemblfungi:YGR067C_mRNA(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)	intact:EBI-747107(isoform-parent)|ensembl:ENSG00000196470(gene)|ensembl:ENST00000356721(transcript)|uniprotkb:Q8IUQ4-2(isoform-parent)	-	crc64:BB936C265B7B263F	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:/qkApijbHr7FKeeSJZ6IczHMf28559292	rogid:M4q06jVbWuq1mGMXvtuFBaMEgZM9606	intact-crc:5C5B43E28E736CC5|rigid:trRKgSdgdVLhq8Xh70Mscr/zkUM	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8IYA8	uniprotkb:P47041	intact:EBI-8638439|intact:EBI-28969497|ensembl:ENSP00000296449|ensembl:ENSP00000391788|ensembl:ENSP00000407837|uniprotkb:C9JJL0|uniprotkb:Q96LP7|intact:MINT-8162095|uniprotkb:Q05DG9	intact:EBI-25889|uniprotkb:D6VWC4|ensemblfungi:YJL058C	psi-mi:iho1_human(display_long)|uniprotkb:IHO1(gene name)|psi-mi:IHO1(display_short)|uniprotkb:CCDC36(gene name synonym)|uniprotkb:Cancer/testis antigen 74(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 36(gene name synonym)	psi-mi:bit61_yeast(display_long)|uniprotkb:YJL058C(locus name)|uniprotkb:J1141(orf name)|uniprotkb:61 kDa binding partner of TOR2 protein(gene name synonym)|uniprotkb:BIT61(gene name)|psi-mi:BIT61(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552268|imex:IM-24995-3638	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000296449|ensembl:ENST00000366429|ensembl:ENSP00000403700|ensembl:ENSP00000391788|ensembl:ENSP00000407837|ensembl:ENSG00000173421(gene)|ensembl:ENST00000296449(transcript)|ensembl:ENST00000438782(transcript)|ensembl:ENST00000452691(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0006310"(DNA recombination)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0042138"(meiotic DNA double-strand break formation)|go:"GO:0048477"(oogenesis)|go:"GO:0060629"(regulation of homologous chromosome segregation)|interpro:IPR031529|mint:Q8IYA8|refseq:XP_011531974.1|refseq:XP_011531975.1|refseq:NP_001128669.1|refseq:NP_835467.2|refseq:XP_006713187.1	refseq:NP_012477.1|sgd:S000003594|dip:DIP-1444N|reactome:R-SCE-1257604|reactome:R-SCE-389357|reactome:R-SCE-5218920|ensemblfungi:YJL058C(gene)|ensemblfungi:YJL058C_mRNA(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005737"(cytoplasm)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0031932"(TORC2 complex)|go:"GO:0038203"(TORC2 signaling)|go:"GO:0071944"(cell periphery)|interpro:IPR013745(HbrB-like)|reactome:R-SCE-6804757	-	comment:mint	crc64:99F0F96840311F4B	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:+TNQLExkhmC1NWqsE240Cx7zFVU9606	rogid:H+zcKwbWL90wsmvD9TfWYmEbRwM559292	intact-crc:3DE463AA6C8478D0|rigid:7jlmiMLt3QumiVKx94sv7aao7xc	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8IXK0-5	uniprotkb:P35184	intact:EBI-11527347|ensembl:ENSP00000507877	intact:EBI-17971|uniprotkb:D6VVU2|ensemblfungi:YIR012W	psi-mi:q8ixk0-5(display_long)|uniprotkb:EDR2(gene name synonym)|uniprotkb:Early development regulatory protein 2(gene name synonym)|uniprotkb:PH2(gene name synonym)|uniprotkb:PHC2(gene name)|psi-mi:PHC2(display_short)	psi-mi:sqt1_yeast(display_long)|uniprotkb:YIB12W(orf name)|uniprotkb:YIR012W(locus name)|uniprotkb:SQT1(gene name)|psi-mi:SQT1(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552244|imex:IM-24995-3632	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000134686(gene)|ensembl:ENST00000683057(transcript)|intact:EBI-713786(isoform-parent)|uniprotkb:Q8IXK0-5(isoform-parent)	refseq:NP_012277.1|sgd:S000001451|ensemblfungi:YIR012W_mRNA(transcript)|ensemblfungi:YIR012W(gene)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|rcsb pdb:4ZOV|rcsb pdb:4ZOX|rcsb pdb:5AMS|dip:DIP-2508N|mint:P35184	-	isoform-comment:No experimental confirmation available.	crc64:981D566076B0C881	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:bkZ10pedX8mCMrcppjyd4tl7hm09606	rogid:u/Q5uAjR85ZD3op0nHiN20IVCLY559292	intact-crc:943EE10C9E12CD2B|rigid:Wn06aGS6Uorm+NPpnOaPqfFHt+U	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8IYA8	uniprotkb:P53038	intact:EBI-8638439|intact:EBI-28969497|ensembl:ENSP00000296449|ensembl:ENSP00000391788|ensembl:ENSP00000407837|uniprotkb:C9JJL0|uniprotkb:Q96LP7|intact:MINT-8162095|uniprotkb:Q05DG9	intact:EBI-19106|uniprotkb:D6VUN1|ensemblfungi:YGR099W	psi-mi:iho1_human(display_long)|uniprotkb:IHO1(gene name)|psi-mi:IHO1(display_short)|uniprotkb:CCDC36(gene name synonym)|uniprotkb:Cancer/testis antigen 74(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 36(gene name synonym)	psi-mi:tel2_yeast(display_long)|uniprotkb:YGR099W(locus name)|uniprotkb:TEL2(gene name)|psi-mi:TEL2(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552276|imex:IM-24995-3640	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000296449|ensembl:ENST00000366429|ensembl:ENSP00000403700|ensembl:ENSP00000391788|ensembl:ENSP00000407837|ensembl:ENSG00000173421(gene)|ensembl:ENST00000296449(transcript)|ensembl:ENST00000438782(transcript)|ensembl:ENST00000452691(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0006310"(DNA recombination)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0042138"(meiotic DNA double-strand break formation)|go:"GO:0048477"(oogenesis)|go:"GO:0060629"(regulation of homologous chromosome segregation)|interpro:IPR031529|mint:Q8IYA8|refseq:XP_011531974.1|refseq:XP_011531975.1|refseq:NP_001128669.1|refseq:NP_835467.2|refseq:XP_006713187.1	sgd:S000003331|ensemblfungi:YGR099W(gene)|ensemblfungi:YGR099W_mRNA(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0005829"(cytosol)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0034502"(protein localization to chromosome)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0070209"(ASTRA complex)|interpro:IPR019337|interpro:IPR038528|rcsb pdb:3O4Z|refseq:NP_011613.3|dip:DIP-1245N|mint:P53038	-	comment:mint	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:+TNQLExkhmC1NWqsE240Cx7zFVU9606	rogid:SZibPBili0M8YgHIwxf+sKkLk+M559292	intact-crc:90763784991B3193|rigid:XUwRPk82ZxXogZH7flupK9k8kbk	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8IYA8	uniprotkb:Q12527	intact:EBI-8638439|intact:EBI-28969497|ensembl:ENSP00000296449|ensembl:ENSP00000391788|ensembl:ENSP00000407837|uniprotkb:C9JJL0|uniprotkb:Q96LP7|intact:MINT-8162095|uniprotkb:Q05DG9	intact:EBI-31977|uniprotkb:D6W457|ensemblfungi:YPR049C	psi-mi:iho1_human(display_long)|uniprotkb:IHO1(gene name)|psi-mi:IHO1(display_short)|uniprotkb:CCDC36(gene name synonym)|uniprotkb:Cancer/testis antigen 74(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 36(gene name synonym)	psi-mi:atg11_yeast(display_long)|uniprotkb:Cytoplasm to vacuole targeting protein 9(gene name synonym)|uniprotkb:ATG11(gene name)|psi-mi:ATG11(display_short)|uniprotkb:CVT9(gene name synonym)|uniprotkb:YPR049C(locus name)|uniprotkb:YP9499.07c(orf name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552272|imex:IM-24995-3639	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000296449|ensembl:ENST00000366429|ensembl:ENSP00000403700|ensembl:ENSP00000391788|ensembl:ENSP00000407837|ensembl:ENSG00000173421(gene)|ensembl:ENST00000296449(transcript)|ensembl:ENST00000438782(transcript)|ensembl:ENST00000452691(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0006310"(DNA recombination)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0042138"(meiotic DNA double-strand break formation)|go:"GO:0048477"(oogenesis)|go:"GO:0060629"(regulation of homologous chromosome segregation)|interpro:IPR031529|mint:Q8IYA8|refseq:XP_011531974.1|refseq:XP_011531975.1|refseq:NP_001128669.1|refseq:NP_835467.2|refseq:XP_006713187.1	refseq:NP_015374.1|sgd:S000006253|dip:DIP-1492N|mint:Q12527|ensemblfungi:YPR049C(gene)|ensemblfungi:YPR049C_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000149"(SNARE binding)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0006914"(autophagy)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0034629"|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061709"(reticulophagy)|go:"GO:0140255"(regulation of cellular response to phosphate starvation)|go:"GO:1990316"(Atg1/ULK1 kinase complex)|go:"GO:2000786"(positive regulation of autophagosome assembly)|interpro:IPR019460|interpro:IPR040040|rcsb pdb:6VZF|reactome:R-SCE-1632852	-	comment:mint	crc64:A904B92E9AE79449	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:+TNQLExkhmC1NWqsE240Cx7zFVU9606	rogid:26PElwvrl3YKwoQU7YdkmR0ln3o559292	intact-crc:122E1DD74850DD8E|rigid:yVhxABq4IWXZfrlw9ybCozncEO0	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q06678	uniprotkb:Q8IYF3-3	intact:EBI-392|uniprotkb:D6VSV4|ensemblfungi:YDR322W	intact:EBI-11523345|ensembl:ENSP00000363453	psi-mi:rm35_yeast(display_long)|uniprotkb:MRPL35(gene name)|psi-mi:MRPL35(display_short)|uniprotkb:YDR322W(locus name)|uniprotkb:D9798.5(orf name)|uniprotkb:YmL35(gene name synonym)|uniprotkb:Mitochondrial large ribosomal subunit protein mL38(gene name synonym)	psi-mi:q8iyf3-3(display_long)|uniprotkb:TEX11(gene name)|psi-mi:TEX11(display_short)|uniprotkb:Protein ZIP4 homolog(gene name synonym)|uniprotkb:ZIP4(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552312|imex:IM-24995-3649	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010608.1|sgd:S000002730|ensemblfungi:YDR322W(gene)|ensemblfungi:YDR322W_mRNA(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0030162"(regulation of proteolysis)|go:"GO:0030414"(peptidase inhibitor activity)|go:"GO:0046578"(regulation of Ras protein signal transduction)|interpro:IPR008914(Phosphatidylethanolamine-binding protein PEBP)|interpro:IPR035810|interpro:IPR036610|rcsb pdb:3J6B|rcsb pdb:5MRC|rcsb pdb:5MRE|rcsb pdb:5MRF|dip:DIP-6832N|mint:Q06678	ensembl:ENSG00000120498(gene)|ensembl:ENST00000374333(transcript)|intact:EBI-742397(isoform-parent)|uniprotkb:Q8IYF3-3(isoform-parent)	-	crc64:C6A2C973121FF555	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:yeCXJ6cEZO5bkf31Et3mVexib3A559292	rogid:PUAMFmnm5ZV2rnJ1rhm9ZeRCixg9606	intact-crc:F661EACFA7EE48FF|rigid:lazbbfxyaIRV1E+N0HRaOp/7iZU	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8IYF3-3	uniprotkb:P28004	intact:EBI-11523345|ensembl:ENSP00000363453	intact:EBI-20640|uniprotkb:D6VPI6|ensemblfungi:YAL032C	psi-mi:q8iyf3-3(display_long)|uniprotkb:TEX11(gene name)|psi-mi:TEX11(display_short)|uniprotkb:Protein ZIP4 homolog(gene name synonym)|uniprotkb:ZIP4(gene name synonym)	psi-mi:prp45_yeast(display_long)|uniprotkb:YAL032C(locus name)|uniprotkb:PRP45(gene name)|psi-mi:PRP45(display_short)|uniprotkb:FUN20(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552308|imex:IM-24995-3648	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000120498(gene)|ensembl:ENST00000374333(transcript)|intact:EBI-742397(isoform-parent)|uniprotkb:Q8IYF3-3(isoform-parent)	refseq:NP_009370.1|sgd:S000000030|ensemblfungi:YAL032C(gene)|ensemblfungi:YAL032C_mRNA(transcript)|go:"GO:0000350"(generation of catalytic spliceosome for second transesterification step)|go:"GO:0005634"(nucleus)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|interpro:IPR004015(SKIP/SNW)|interpro:IPR017862|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|dip:DIP-2774N|mint:P28004	-	-	crc64:FE5A724186D7FE84	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:PUAMFmnm5ZV2rnJ1rhm9ZeRCixg9606	rogid:qoHF1UsO3k+JOTOfigSuy2P84/k559292	intact-crc:AB64D28B4750B11B|rigid:bFlrER27s5qGZWGKEo74cSVGA2Y	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8IYF3-3	uniprotkb:P87108	intact:EBI-11523345|ensembl:ENSP00000363453	intact:EBI-9115|ensemblfungi:YHR005C-A|uniprotkb:D3DKU9	psi-mi:q8iyf3-3(display_long)|uniprotkb:TEX11(gene name)|psi-mi:TEX11(display_short)|uniprotkb:Protein ZIP4 homolog(gene name synonym)|uniprotkb:ZIP4(gene name synonym)	psi-mi:tim10_yeast(display_long)|uniprotkb:MRS11(gene name synonym)|uniprotkb:YHR005BC(orf name)|uniprotkb:YHR005C-A(locus name)|uniprotkb:TIM10(gene name)|psi-mi:TIM10(display_short)|uniprotkb:Mitochondrial intermembrane protein MRS11(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552304|imex:IM-24995-3647	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000120498(gene)|ensembl:ENST00000374333(transcript)|intact:EBI-742397(isoform-parent)|uniprotkb:Q8IYF3-3(isoform-parent)	ensemblfungi:YHR005C-A(gene)|ensemblfungi:YHR005C-A_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0042719"(mitochondrial intermembrane space protein transporter complex)|go:"GO:0045039"(protein insertion into mitochondrial inner membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0140318"(protein transporter activity)|interpro:IPR004217(Zinc finger, Tim10/DDP-type)|interpro:IPR027100|interpro:IPR035427|rcsb pdb:3DXR|rcsb pdb:6LO8|reactome:R-SCE-1268020|refseq:NP_011869.1|sgd:S000003530|dip:DIP-1141N|mint:P87108	-	-	crc64:70DD4764B944FF17	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:PUAMFmnm5ZV2rnJ1rhm9ZeRCixg9606	rogid:3AGstULCT5EBmHEk0EGsz9Rk9YA559292	intact-crc:84A917BF03CAB51F|rigid:qwPzymulS4vtLWgly/ubvTgvMCU	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P32902	uniprotkb:Q8IYF3-3	intact:EBI-16248|ensemblfungi:YHL004W|uniprotkb:D3DKR0	intact:EBI-11523345|ensembl:ENSP00000363453	psi-mi:rt04_yeast(display_long)|uniprotkb:MRP4(gene name)|psi-mi:MRP4(display_short)|uniprotkb:MRP4A(gene name synonym)|uniprotkb:Mitochondrial small ribosomal subunit protein uS2m(gene name synonym)|uniprotkb:YHL004W(locus name)	psi-mi:q8iyf3-3(display_long)|uniprotkb:TEX11(gene name)|psi-mi:TEX11(display_short)|uniprotkb:Protein ZIP4 homolog(gene name synonym)|uniprotkb:ZIP4(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552300|imex:IM-24995-3646	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YHL004W(gene)|ensemblfungi:YHL004W_mRNA(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR001865(Ribosomal protein S2)|interpro:IPR005706(Ribosomal protein S2, bacterial-type)|interpro:IPR018130|interpro:IPR023591|rcsb pdb:5MRC|rcsb pdb:5MRE|rcsb pdb:5MRF|refseq:NP_011859.1|sgd:S000000996|dip:DIP-5035N|mint:P32902	ensembl:ENSG00000120498(gene)|ensembl:ENST00000374333(transcript)|intact:EBI-742397(isoform-parent)|uniprotkb:Q8IYF3-3(isoform-parent)	-	crc64:81A1CB33134BC559	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:BlL3W6HUN+uAKF/AxwlV1zT5YZQ559292	rogid:PUAMFmnm5ZV2rnJ1rhm9ZeRCixg9606	intact-crc:9D66A7BD62F87DDB|rigid:5O6jZs2BB4nz3YQQSmrfCo54JsY	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P14907	uniprotkb:Q8IYF3-3	intact:EBI-12265|uniprotkb:D6VWE3	intact:EBI-11523345|ensembl:ENSP00000363453	psi-mi:nsp1_yeast(display_long)|uniprotkb:NSP1(gene name)|psi-mi:NSP1(display_short)|uniprotkb:YJL041W(locus name)|uniprotkb:J1207(orf name)|uniprotkb:Nuclear pore protein NSP1(gene name synonym)|uniprotkb:Nucleoskeletal-like protein(gene name synonym)|uniprotkb:p110(gene name synonym)	psi-mi:q8iyf3-3(display_long)|uniprotkb:TEX11(gene name)|psi-mi:TEX11(display_short)|uniprotkb:Protein ZIP4 homolog(gene name synonym)|uniprotkb:ZIP4(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552296|imex:IM-24995-3645	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005643"(nuclear pore)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006409"(tRNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034399"(nuclear periphery)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0044615"(nuclear pore nuclear basket)|go:"GO:0097064"(ncRNA export from nucleus)|interpro:IPR007758(Nucleoporin, Nsp1-like, C-terminal)|interpro:IPR026010|rcsb pdb:1O6O|refseq:NP_012494.3|sgd:S000003577|mint:P14907|dip:DIP-1484N	ensembl:ENSG00000120498(gene)|ensembl:ENST00000374333(transcript)|intact:EBI-742397(isoform-parent)|uniprotkb:Q8IYF3-3(isoform-parent)	-	crc64:A258003CB1917810	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:wFdC6D8JzkhJpF+k3qtnFj9+4pA559292	rogid:PUAMFmnm5ZV2rnJ1rhm9ZeRCixg9606	intact-crc:DA4DA16929F39833|rigid:Vos9JzohYWyh3B2VJRQIX3CQZAE	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P47041	uniprotkb:Q8IYF3-3	intact:EBI-25889|uniprotkb:D6VWC4|ensemblfungi:YJL058C	intact:EBI-11523345|ensembl:ENSP00000363453	psi-mi:bit61_yeast(display_long)|uniprotkb:YJL058C(locus name)|uniprotkb:J1141(orf name)|uniprotkb:61 kDa binding partner of TOR2 protein(gene name synonym)|uniprotkb:BIT61(gene name)|psi-mi:BIT61(display_short)	psi-mi:q8iyf3-3(display_long)|uniprotkb:TEX11(gene name)|psi-mi:TEX11(display_short)|uniprotkb:Protein ZIP4 homolog(gene name synonym)|uniprotkb:ZIP4(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552292|imex:IM-24995-3644	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012477.1|sgd:S000003594|dip:DIP-1444N|reactome:R-SCE-1257604|reactome:R-SCE-389357|reactome:R-SCE-5218920|ensemblfungi:YJL058C(gene)|ensemblfungi:YJL058C_mRNA(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005737"(cytoplasm)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0031932"(TORC2 complex)|go:"GO:0038203"(TORC2 signaling)|go:"GO:0071944"(cell periphery)|interpro:IPR013745(HbrB-like)|reactome:R-SCE-6804757	ensembl:ENSG00000120498(gene)|ensembl:ENST00000374333(transcript)|intact:EBI-742397(isoform-parent)|uniprotkb:Q8IYF3-3(isoform-parent)	-	crc64:99F0F96840311F4B	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:H+zcKwbWL90wsmvD9TfWYmEbRwM559292	rogid:PUAMFmnm5ZV2rnJ1rhm9ZeRCixg9606	intact-crc:7FF915145C3056E3|rigid:GYyPQ0bcffXr+RKuIm21GO94QJE	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8IYA8	uniprotkb:Q06819	intact:EBI-8638439|intact:EBI-28969497|ensembl:ENSP00000296449|ensembl:ENSP00000391788|ensembl:ENSP00000407837|uniprotkb:C9JJL0|uniprotkb:Q96LP7|intact:MINT-8162095|uniprotkb:Q05DG9	intact:EBI-166|ensemblfungi:YPR082C|uniprotkb:D6W484	psi-mi:iho1_human(display_long)|uniprotkb:IHO1(gene name)|psi-mi:IHO1(display_short)|uniprotkb:CCDC36(gene name synonym)|uniprotkb:Cancer/testis antigen 74(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 36(gene name synonym)	psi-mi:dib1_yeast(display_long)|uniprotkb:DIB1(gene name)|psi-mi:DIB1(display_short)|uniprotkb:CDH1(gene name synonym)|uniprotkb:SNU16(gene name synonym)|uniprotkb:YPR082C(locus name)|uniprotkb:P9513.12(orf name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552288|imex:IM-24995-3643	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000296449|ensembl:ENST00000366429|ensembl:ENSP00000403700|ensembl:ENSP00000391788|ensembl:ENSP00000407837|ensembl:ENSG00000173421(gene)|ensembl:ENST00000296449(transcript)|ensembl:ENST00000438782(transcript)|ensembl:ENST00000452691(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0006310"(DNA recombination)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0042138"(meiotic DNA double-strand break formation)|go:"GO:0048477"(oogenesis)|go:"GO:0060629"(regulation of homologous chromosome segregation)|interpro:IPR031529|mint:Q8IYA8|refseq:XP_011531974.1|refseq:XP_011531975.1|refseq:NP_001128669.1|refseq:NP_835467.2|refseq:XP_006713187.1	refseq:NP_015407.1|sgd:S000006286|ensemblfungi:YPR082C(gene)|ensemblfungi:YPR082C_mRNA(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005682"(U5 snRNP)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|interpro:IPR004123(mRNA splicing factor, thioredoxin-like U5 snRNP)|interpro:IPR036249|rcsb pdb:3JCM|rcsb pdb:5GAN|rcsb pdb:5GAP|rcsb pdb:5NRL|rcsb pdb:5ZWM|rcsb pdb:5ZWO|dip:DIP-1289N	-	comment:mint	crc64:B8C11278571C57E5	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:+TNQLExkhmC1NWqsE240Cx7zFVU9606	rogid:mRibIpinKPlRNdh60VJj/Z0tjUc559292	intact-crc:313580B504D53F3E|rigid:4GejNbKKpIULMOfZDB67JAlCfpM	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8IYA8	uniprotkb:P32502	intact:EBI-8638439|intact:EBI-28969497|ensembl:ENSP00000296449|ensembl:ENSP00000391788|ensembl:ENSP00000407837|uniprotkb:C9JJL0|uniprotkb:Q96LP7|intact:MINT-8162095|uniprotkb:Q05DG9	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:iho1_human(display_long)|uniprotkb:IHO1(gene name)|psi-mi:IHO1(display_short)|uniprotkb:CCDC36(gene name synonym)|uniprotkb:Cancer/testis antigen 74(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 36(gene name synonym)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552280|imex:IM-24995-3641	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000296449|ensembl:ENST00000366429|ensembl:ENSP00000403700|ensembl:ENSP00000391788|ensembl:ENSP00000407837|ensembl:ENSG00000173421(gene)|ensembl:ENST00000296449(transcript)|ensembl:ENST00000438782(transcript)|ensembl:ENST00000452691(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0006310"(DNA recombination)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0042138"(meiotic DNA double-strand break formation)|go:"GO:0048477"(oogenesis)|go:"GO:0060629"(regulation of homologous chromosome segregation)|interpro:IPR031529|mint:Q8IYA8|refseq:XP_011531974.1|refseq:XP_011531975.1|refseq:NP_001128669.1|refseq:NP_835467.2|refseq:XP_006713187.1	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731	-	comment:mint	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:+TNQLExkhmC1NWqsE240Cx7zFVU9606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:63EB230B6F252457|rigid:aD6ReVsQ4vnRgoWlg+1OttnqWGc	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8IYA8	uniprotkb:P25372	intact:EBI-8638439|intact:EBI-28969497|ensembl:ENSP00000296449|ensembl:ENSP00000391788|ensembl:ENSP00000407837|uniprotkb:C9JJL0|uniprotkb:Q96LP7|intact:MINT-8162095|uniprotkb:Q05DG9	intact:EBI-19616|uniprotkb:D6VR84|ensemblfungi:YCR083W	psi-mi:iho1_human(display_long)|uniprotkb:IHO1(gene name)|psi-mi:IHO1(display_short)|uniprotkb:CCDC36(gene name synonym)|uniprotkb:Cancer/testis antigen 74(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 36(gene name synonym)	psi-mi:trx3_yeast(display_long)|uniprotkb:TRX3(gene name)|psi-mi:TRX3(display_short)|uniprotkb:YCR83W(orf name)|uniprotkb:YCR083W(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552284|imex:IM-24995-3642	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000296449|ensembl:ENST00000366429|ensembl:ENSP00000403700|ensembl:ENSP00000391788|ensembl:ENSP00000407837|ensembl:ENSG00000173421(gene)|ensembl:ENST00000296449(transcript)|ensembl:ENST00000438782(transcript)|ensembl:ENST00000452691(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0006310"(DNA recombination)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0042138"(meiotic DNA double-strand break formation)|go:"GO:0048477"(oogenesis)|go:"GO:0060629"(regulation of homologous chromosome segregation)|interpro:IPR031529|mint:Q8IYA8|refseq:XP_011531974.1|refseq:XP_011531975.1|refseq:NP_001128669.1|refseq:NP_835467.2|refseq:XP_006713187.1	interpro:IPR036249|refseq:NP_010006.1|sgd:S000000679|interpro:IPR017937|interpro:IPR013766(Thioredoxin domain)|rcsb pdb:2OE0|rcsb pdb:2OE1|rcsb pdb:2OE3|ensemblfungi:YCR083W(gene)|ensemblfungi:YCR083W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0015036"(disulfide oxidoreductase activity)|go:"GO:0034599"(cellular response to oxidative stress)|rcsb pdb:5YKW	-	comment:mint	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:+TNQLExkhmC1NWqsE240Cx7zFVU9606	rogid:g0xjGf9GvJRl8iv2qoT5tOs7jXI559292	intact-crc:9B6B8B67082BA6AE|rigid:2zq189Faq2pyv39vLJcAMbQ4yiY	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8IYF3-3	uniprotkb:P26343	intact:EBI-11523345|ensembl:ENSP00000363453	intact:EBI-5489|uniprotkb:D6VX97|ensemblfungi:YKR034W	psi-mi:q8iyf3-3(display_long)|uniprotkb:TEX11(gene name)|psi-mi:TEX11(display_short)|uniprotkb:Protein ZIP4 homolog(gene name synonym)|uniprotkb:ZIP4(gene name synonym)	psi-mi:dal80_yeast(display_long)|uniprotkb:YKR034W(locus name)|uniprotkb:DAL80(gene name)|psi-mi:DAL80(display_short)|uniprotkb:UGA43(gene name synonym)|uniprotkb:Regulatory protein UGA43(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552320|imex:IM-24995-3651	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000120498(gene)|ensembl:ENST00000374333(transcript)|intact:EBI-742397(isoform-parent)|uniprotkb:Q8IYF3-3(isoform-parent)	refseq:NP_012959.1|sgd:S000001742|dip:DIP-2094N|ensemblfungi:YKR034W(gene)|ensemblfungi:YKR034W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042128"(nitrate assimilation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0090295"(nitrogen catabolite repression of transcription)|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR039355	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:PUAMFmnm5ZV2rnJ1rhm9ZeRCixg9606	rogid:Qfoc7DZ+/Nwthc4Hf93+iwuYgVg559292	intact-crc:8442AD248A35F829|rigid:1LkqKzGxU6MFIMhwAGfgH8AZjdQ	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8IYF3-3	uniprotkb:P38763	intact:EBI-11523345|ensembl:ENSP00000363453	intact:EBI-24475|uniprotkb:D3DKW8|ensemblfungi:YHR022C	psi-mi:q8iyf3-3(display_long)|uniprotkb:TEX11(gene name)|psi-mi:TEX11(display_short)|uniprotkb:Protein ZIP4 homolog(gene name synonym)|uniprotkb:ZIP4(gene name synonym)	psi-mi:yhi2_yeast(display_long)|uniprotkb:YHR022C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552316|imex:IM-24995-3650	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000120498(gene)|ensembl:ENST00000374333(transcript)|intact:EBI-742397(isoform-parent)|uniprotkb:Q8IYF3-3(isoform-parent)	refseq:NP_011887.1|sgd:S000001064|dip:DIP-1876N|ensemblfungi:YHR022C(gene)|ensemblfungi:YHR022C_mRNA(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0012505"(endomembrane system)|interpro:IPR001806(Ras GTPase)|interpro:IPR027417|reactome:R-SCE-6811440|reactome:R-SCE-8873719|reactome:R-SCE-8876198	-	-	crc64:8A4A500681EF3D74	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:PUAMFmnm5ZV2rnJ1rhm9ZeRCixg9606	rogid:jcjAXgGlLpgsG473/s41ALnbUQo559292	intact-crc:B71E60E0EF8C4548|rigid:8zgdx4i3Cj+n7krc8HseIoEhcHc	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8N0S2	uniprotkb:P15807	intact:EBI-6872807|ensembl:ENSP00000341282|uniprotkb:Q9BWU4|uniprotkb:B2RC80|uniprotkb:Q9BWU3	intact:EBI-10770|ensemblfungi:YBR213W|uniprotkb:D6VQK9	psi-mi:syce1_human(display_long)|uniprotkb:C10orf94(gene name synonym)|uniprotkb:Cancer/testis antigen 76(gene name synonym)|uniprotkb:SYCE1(gene name)|psi-mi:SYCE1(display_short)	psi-mi:met8_yeast(display_long)|uniprotkb:YBR1461(orf name)|uniprotkb:YBR213W(locus name)|uniprotkb:MET8(gene name)|psi-mi:MET8(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552348|imex:IM-24995-3658	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000171772(gene)|ensembl:ENST00000343131(transcript)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0000801"(central element)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051301"(cell division)|interpro:IPR026676|reactome:R-HSA-1221632|refseq:NP_001137235.1|refseq:NP_570140.1	ensemblfungi:YBR213W(gene)|ensemblfungi:YBR213W_mRNA(transcript)|go:"GO:0000103"(sulfate assimilation)|go:"GO:0004325"(ferrochelatase activity)|go:"GO:0019354"(siroheme biosynthetic process)|go:"GO:0043115"(precorrin-2 dehydrogenase activity)|go:"GO:0051266"(sirohydrochlorin ferrochelatase activity)|interpro:IPR028161|interpro:IPR028162|interpro:IPR028281|interpro:IPR036291|rcsb pdb:1KYQ|refseq:NP_009772.1|sgd:S000000417|mint:P15807|dip:DIP-4944N	-	-	crc64:0EE9A6DE8A43673E	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:qLVqIlFiwZJHFfoyYXV3jrqdd609606	rogid:4Z2yZage0Yi6KB2YM/gANFSLcC0559292	intact-crc:41F666FBAC285A39|rigid:hD30oL8Wp0apbcFpk6VS7i9/3u4	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8N0S2	uniprotkb:P38340	intact:EBI-6872807|ensembl:ENSP00000341282|uniprotkb:Q9BWU4|uniprotkb:B2RC80|uniprotkb:Q9BWU3	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:syce1_human(display_long)|uniprotkb:C10orf94(gene name synonym)|uniprotkb:Cancer/testis antigen 76(gene name synonym)|uniprotkb:SYCE1(gene name)|psi-mi:SYCE1(display_short)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552344|imex:IM-24995-3657	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000171772(gene)|ensembl:ENST00000343131(transcript)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0000801"(central element)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051301"(cell division)|interpro:IPR026676|reactome:R-HSA-1221632|refseq:NP_001137235.1|refseq:NP_570140.1	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F	-	-	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:qLVqIlFiwZJHFfoyYXV3jrqdd609606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:8AE29C19B22375E9|rigid:D4In7CizkteBP9/zVwBSbM0sqmA	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8IZ13	uniprotkb:P32381	intact:EBI-7186123|ensembl:ENSP00000386184|ensembl:ENSP00000428831|uniprotkb:Q9H5S8|uniprotkb:D3DQJ9|intact:MINT-8163956|intact:MINT-8247520|uniprotkb:Q9UH87	intact:EBI-2927|uniprotkb:D6VRW3|ensemblfungi:YDL029W	psi-mi:zbed8_human(display_long)|uniprotkb:ZBED8(gene name)|psi-mi:ZBED8(display_short)|uniprotkb:Buster3(gene name synonym)|uniprotkb:C5orf54(gene name synonym)|uniprotkb:Transposon-derived Buster3 transposase-like protein(gene name synonym)|uniprotkb:Zinc finger BED domain-containing protein 8(gene name synonym)	psi-mi:arp2_yeast(display_long)|uniprotkb:ACT2(gene name synonym)|uniprotkb:YDL029W(locus name)|uniprotkb:D2778(orf name)|uniprotkb:ARP2(gene name)|psi-mi:ARP2(display_short)|uniprotkb:Actin-like protein ARP2(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552340|imex:IM-24995-3656	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001290180.1|ensembl:ENSG00000221886(gene)|ensembl:ENST00000408953(transcript)|ensembl:ENST00000523213(transcript)|go:"GO:0005654"(nucleoplasm)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR025398|mint:Q8IZ13|refseq:NP_071373.2	refseq:NP_010255.1|sgd:S000002187|dip:DIP-2217N|mint:P32381|ensemblfungi:YDL029W(gene)|ensemblfungi:YDL029W_mRNA(transcript)|go:"GO:0000001"(mitochondrion inheritance)|go:"GO:0003779"(actin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0030476"(ascospore wall assembly)|go:"GO:0030479"(actin cortical patch)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0044396"(actin cortical patch organization)|go:"GO:0051654"(establishment of mitochondrion localization)|interpro:IPR004000(Actin/actin-like)|interpro:IPR020902|interpro:IPR043129|reactome:R-SCE-2029482|reactome:R-SCE-5663213|reactome:R-SCE-6798695|reactome:R-SCE-8856828	-	comment:mint	crc64:4C9E8952B477A1B9	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:UMQXSqCyTL0MlOJybHaWQazjfPg9606	rogid:baSDcw/PZH3Z8YHhIcYqtlNO3mw559292	intact-crc:F05D9D4E66B21FF3|rigid:6GEbCj29ogHagPn37NpLBoQxNaw	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P46948	uniprotkb:Q8IYX7	intact:EBI-1788|uniprotkb:D6VUX7|ensemblfungi:YGR195W	intact:EBI-3957636|ensembl:ENSP00000369907|intact:EBI-10174528|uniprotkb:A8K880|uniprotkb:Q5VY58	psi-mi:rrp41_yeast(display_long)|uniprotkb:SKI6(gene name)|psi-mi:SKI6(display_short)|uniprotkb:YGR195W(locus name)|uniprotkb:G7587(orf name)|uniprotkb:ECM20(gene name synonym)|uniprotkb:Ribosomal RNA-processing protein 41(gene name synonym)|uniprotkb:Superkiller protein 6(gene name synonym)|uniprotkb:Extracellular mutant protein 20(gene name synonym)|uniprotkb:RRP41(gene name synonym)	psi-mi:saxo1_human(display_long)|uniprotkb:SAXO1(gene name)|psi-mi:SAXO1(display_short)|uniprotkb:C9orf138(gene name synonym)|uniprotkb:FAM154A(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552336|imex:IM-24995-3655	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003427|refseq:NP_011711.3|dip:DIP-2083N|mint:P46948|ensemblfungi:YGR195W(gene)|ensemblfungi:YGR195W_mRNA(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034473"(U1 snRNA 3'-end processing)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0034476"(U5 snRNA 3'-end processing)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071039"(nuclear polyadenylation-dependent CUT catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345|rcsb pdb:2WP8|rcsb pdb:4IFD|rcsb pdb:4OO1|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5G06|rcsb pdb:5JEA|rcsb pdb:5K36|rcsb pdb:5OKZ|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-429958|reactome:R-SCE-450385|reactome:R-SCE-450513|reactome:R-SCE-6791226	ensembl:ENSG00000155875(gene)|ensembl:ENST00000380534(transcript)|go:"GO:0005814"(centriole)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0008017"(microtubule binding)|go:"GO:0009631"(cold acclimation)|go:"GO:0030030"(cell projection organization)|go:"GO:0031514"(motile cilium)|go:"GO:0034453"(microtubule anchoring)|go:"GO:0036064"(ciliary basal body)|go:"GO:0036126"(sperm flagellum)|go:"GO:0045724"(positive regulation of cilium assembly)|go:"GO:0050821"(protein stabilization)|go:"GO:0070417"(cellular response to cold)|interpro:IPR033336|refseq:NP_714918.2|refseq:NP_001273978.1|refseq:NP_001273979.1	-	crc64:C80EFFB528A43044	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:I7vEo0EUB1jZO+3v12H0LwVbgmo559292	rogid:34It0miSDTtv5wwJ+ERHXJzWRiQ9606	intact-crc:321F0B789AFAF395|rigid:tnCrBQySz/SLCacRedV2TfSkLr0	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8IYX7	uniprotkb:P53286	intact:EBI-3957636|ensembl:ENSP00000369907|intact:EBI-10174528|uniprotkb:A8K880|uniprotkb:Q5VY58	intact:EBI-3796|uniprotkb:D6VUS2|ensemblfungi:YGR142W	psi-mi:saxo1_human(display_long)|uniprotkb:SAXO1(gene name)|psi-mi:SAXO1(display_short)|uniprotkb:C9orf138(gene name synonym)|uniprotkb:FAM154A(gene name synonym)	psi-mi:btn2_yeast(display_long)|uniprotkb:YGR142W(locus name)|uniprotkb:BTN2(gene name)|psi-mi:BTN2(display_short)|uniprotkb:Batten disease protein 2(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552332|imex:IM-24995-3654	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000155875(gene)|ensembl:ENST00000380534(transcript)|go:"GO:0005814"(centriole)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0008017"(microtubule binding)|go:"GO:0009631"(cold acclimation)|go:"GO:0030030"(cell projection organization)|go:"GO:0031514"(motile cilium)|go:"GO:0034453"(microtubule anchoring)|go:"GO:0036064"(ciliary basal body)|go:"GO:0036126"(sperm flagellum)|go:"GO:0045724"(positive regulation of cilium assembly)|go:"GO:0050821"(protein stabilization)|go:"GO:0070417"(cellular response to cold)|interpro:IPR033336|refseq:NP_714918.2|refseq:NP_001273978.1|refseq:NP_001273979.1	sgd:S000003374|refseq:NP_011658.3|dip:DIP-5534N|mint:P53286|ensemblfungi:YGR142W(gene)|ensemblfungi:YGR142W_mRNA(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005634"(nucleus)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006865"(amino acid transport)|go:"GO:0006885"(regulation of pH)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051087"(chaperone binding)|go:"GO:0140311"(protein sequestering activity)	-	-	crc64:E7AE1EB1E3612F3E	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:34It0miSDTtv5wwJ+ERHXJzWRiQ9606	rogid:Cu27xkwGMNyS4zLvUaG1UeH2mE0559292	intact-crc:A0C4DCB8F67D441A|rigid:TDKUHObbGC3hTL1Ypp6YkuVWUjU	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8IYX7	uniprotkb:P15303	intact:EBI-3957636|ensembl:ENSP00000369907|intact:EBI-10174528|uniprotkb:A8K880|uniprotkb:Q5VY58	intact:EBI-16584|ensemblfungi:YPR181C|uniprotkb:D6W4I1	psi-mi:saxo1_human(display_long)|uniprotkb:SAXO1(gene name)|psi-mi:SAXO1(display_short)|uniprotkb:C9orf138(gene name synonym)|uniprotkb:FAM154A(gene name synonym)	psi-mi:sec23_yeast(display_long)|uniprotkb:SEC23(gene name)|psi-mi:SEC23(display_short)|uniprotkb:P9705.14(orf name)|uniprotkb:YPR181C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552328|imex:IM-24995-3653	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000155875(gene)|ensembl:ENST00000380534(transcript)|go:"GO:0005814"(centriole)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0008017"(microtubule binding)|go:"GO:0009631"(cold acclimation)|go:"GO:0030030"(cell projection organization)|go:"GO:0031514"(motile cilium)|go:"GO:0034453"(microtubule anchoring)|go:"GO:0036064"(ciliary basal body)|go:"GO:0036126"(sperm flagellum)|go:"GO:0045724"(positive regulation of cilium assembly)|go:"GO:0050821"(protein stabilization)|go:"GO:0070417"(cellular response to cold)|interpro:IPR033336|refseq:NP_714918.2|refseq:NP_001273978.1|refseq:NP_001273979.1	refseq:NP_015507.1|sgd:S000006385|ensemblfungi:YPR181C(gene)|ensemblfungi:YPR181C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003400"(regulation of COPII vesicle coating)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016236"(macroautophagy)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0061709"(reticulophagy)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:0090110"(COPII-coated vesicle cargo loading)|interpro:IPR006895(Zinc finger, Sec23/Sec24-type)|interpro:IPR006896(Sec23/Sec24 trunk region)|interpro:IPR006900(Sec23/Sec24 helical region)|interpro:IPR007123(Gelsolin region)|interpro:IPR012990(Sec23/Sec24 beta-sandwich)|interpro:IPR029006|interpro:IPR036174|interpro:IPR036175|interpro:IPR036180|interpro:IPR036465|interpro:IPR037364|interpro:IPR037550|rcsb pdb:1M2O|rcsb pdb:2QTV|rcsb pdb:4BZI|rcsb pdb:6GNI|rcsb pdb:6ZGA|reactome:R-SCE-204005|reactome:R-SCE-5694530|reactome:R-SCE-983170|rcsb pdb:1M2V|dip:DIP-2232N|mint:P15303	-	-	crc64:69811913848265FB	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:34It0miSDTtv5wwJ+ERHXJzWRiQ9606	rogid:IqC3qOrbef6aMHBztUW5+7DZ4IQ559292	intact-crc:B7947E3B9F645132|rigid:CcnZTitK+IXIqlud5ojOCUOJdcs	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q02831	uniprotkb:Q8IYF3-3	intact:EBI-31828|uniprotkb:D6W3T9|ensemblfungi:YPL077C	intact:EBI-11523345|ensembl:ENSP00000363453	psi-mi:yp077_yeast(display_long)|uniprotkb:YPL077C(locus name)	psi-mi:q8iyf3-3(display_long)|uniprotkb:TEX11(gene name)|psi-mi:TEX11(display_short)|uniprotkb:Protein ZIP4 homolog(gene name synonym)|uniprotkb:ZIP4(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552324|imex:IM-24995-3652	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005998|refseq:NP_015248.1|dip:DIP-4022N|ensemblfungi:YPL077C(gene)|ensemblfungi:YPL077C_mRNA(transcript)	ensembl:ENSG00000120498(gene)|ensembl:ENST00000374333(transcript)|intact:EBI-742397(isoform-parent)|uniprotkb:Q8IYF3-3(isoform-parent)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:yqOn4GWKNmFZ7UvGmyBEpgoyKlA559292	rogid:PUAMFmnm5ZV2rnJ1rhm9ZeRCixg9606	intact-crc:013D1B2D3517B563|rigid:yEHXFav+2oeLW097llC8xw/biz0	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P38340	uniprotkb:Q8N6K7-2	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-11528848|ensembl:ENSP00000324874	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:q8n6k7-2(display_long)|uniprotkb:SAMD3(gene name)|psi-mi:SAMD3(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552388|imex:IM-24995-3668	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F	intact:EBI-748741(isoform-parent)|ensembl:ENSG00000164483(gene)|ensembl:ENST00000324172(transcript)|uniprotkb:Q8N6K7-2(isoform-parent)	-	crc64:66699F37B0013088	isoform-comment:No experimental confirmation available.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:2ZsHFOFMqw/yebw24QlvgpYFVso9606	intact-crc:F0B09EFA12C6A26D|rigid:bEcj5U8qypoTMCNPiWZwGC6WGYY	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P53286	uniprotkb:Q8N6K7-2	intact:EBI-3796|uniprotkb:D6VUS2|ensemblfungi:YGR142W	intact:EBI-11528848|ensembl:ENSP00000324874	psi-mi:btn2_yeast(display_long)|uniprotkb:YGR142W(locus name)|uniprotkb:BTN2(gene name)|psi-mi:BTN2(display_short)|uniprotkb:Batten disease protein 2(gene name synonym)	psi-mi:q8n6k7-2(display_long)|uniprotkb:SAMD3(gene name)|psi-mi:SAMD3(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552384|imex:IM-24995-3667	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003374|refseq:NP_011658.3|dip:DIP-5534N|mint:P53286|ensemblfungi:YGR142W(gene)|ensemblfungi:YGR142W_mRNA(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005634"(nucleus)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006865"(amino acid transport)|go:"GO:0006885"(regulation of pH)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051087"(chaperone binding)|go:"GO:0140311"(protein sequestering activity)	intact:EBI-748741(isoform-parent)|ensembl:ENSG00000164483(gene)|ensembl:ENST00000324172(transcript)|uniprotkb:Q8N6K7-2(isoform-parent)	-	crc64:E7AE1EB1E3612F3E	isoform-comment:No experimental confirmation available.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Cu27xkwGMNyS4zLvUaG1UeH2mE0559292	rogid:2ZsHFOFMqw/yebw24QlvgpYFVso9606	intact-crc:F0DD71773F999D98|rigid:MmC7hO4tzKjiNILYyGE8qh1H7wo	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8N0S2	uniprotkb:Q06543	intact:EBI-6872807|ensembl:ENSP00000341282|uniprotkb:Q9BWU4|uniprotkb:B2RC80|uniprotkb:Q9BWU3	intact:EBI-33132|uniprotkb:D6VYP1|ensemblfungi:YLR243W	psi-mi:syce1_human(display_long)|uniprotkb:C10orf94(gene name synonym)|uniprotkb:Cancer/testis antigen 76(gene name synonym)|uniprotkb:SYCE1(gene name)|psi-mi:SYCE1(display_short)	psi-mi:gpn3_yeast(display_long)|uniprotkb:GPN3(gene name)|psi-mi:GPN3(display_short)|uniprotkb:YLR243W(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552352|imex:IM-24995-3659	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000171772(gene)|ensembl:ENST00000343131(transcript)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0000801"(central element)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051301"(cell division)|interpro:IPR026676|reactome:R-HSA-1221632|refseq:NP_001137235.1|refseq:NP_570140.1	refseq:NP_013344.1|sgd:S000004233|dip:DIP-1911N|ensemblfungi:YLR243W(gene)|ensemblfungi:YLR243W_mRNA(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007064"(mitotic sister chromatid cohesion)|interpro:IPR004130(Protein of unknown function, ATP binding)|interpro:IPR027417|interpro:IPR030228	-	-	crc64:96E478B8DD5988BB	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:qLVqIlFiwZJHFfoyYXV3jrqdd609606	rogid:XGJg0/XoYEbfio5kpjB/7Q9Cvjc559292	intact-crc:750634F6E2549F97|rigid:nA5S7YO2+jToqKP3IVfrj1+eboU	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P32464	uniprotkb:Q8N3J3-3	intact:EBI-8859|ensemblfungi:YKL189W|uniprotkb:D6VX11	intact:EBI-11061081|ensembl:ENSP00000245382	psi-mi:hym1_yeast(display_long)|uniprotkb:YKL189W(locus name)|uniprotkb:HYM1(gene name)|psi-mi:HYM1(display_short)	psi-mi:q8n3j3-3(display_long)|uniprotkb:HROB(gene name)|psi-mi:HROB(display_short)|uniprotkb:C17orf53(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552356|imex:IM-24995-3660	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YKL189W(gene)|ensemblfungi:YKL189W_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0000920"(septum digestion after cytokinesis)|go:"GO:0005933"(cellular bud)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007118"(budding cell apical bud growth)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043332"(mating projection tip)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0044732"(mitotic spindle pole body)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013878(Mo25-like)|interpro:IPR016024(Armadillo-type fold)|reactome:R-SCE-6798695|refseq:NP_012732.1|sgd:S000001672|mint:P32464|dip:DIP-5425N	intact:EBI-8465499(isoform-parent)|uniprotkb:Q8N3J3-3(isoform-parent)|ensembl:ENSG00000125319(gene)|ensembl:ENST00000245382(transcript)	-	crc64:F48860754C892BA9	isoform-comment:No experimental confirmation available.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:pOlQFFuYgFzmqf3ZGUVkBj9h7Uc559292	rogid:CV8rVs1P1HH0w/igNSebho0bupA9606	intact-crc:3521D38B79EB1FCB|rigid:4axyQ/CKyNEmBlfsCq5Oe22Q6PE	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8N4C7	uniprotkb:P25635	intact:EBI-8484990|intact:MINT-6940674|ensembl:ENSP00000320679	intact:EBI-14332|uniprotkb:P25633|uniprotkb:P25636|uniprotkb:D6VR63|ensemblfungi:YCR057C	psi-mi:stx19_human(display_long)|uniprotkb:STX19(gene name)|psi-mi:STX19(display_short)	psi-mi:pwp2_yeast(display_long)|uniprotkb:PWP2(gene name)|psi-mi:PWP2(display_short)|uniprotkb:UTP1(gene name synonym)|uniprotkb:YCR057C(locus name)|uniprotkb:YCR55C/YCR57C/YCR58C(orf name)|uniprotkb:U3 small nucleolar RNA-associated protein 1(gene name synonym)|uniprotkb:U three protein 1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552360|imex:IM-24995-3661	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011511144.1|refseq:NP_001001850.1|ensembl:ENSG00000178750(gene)|ensembl:ENST00000315099(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006887"(exocytosis)|go:"GO:0006906"(vesicle fusion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0048278"(vesicle docking)|go:"GO:0048787"(presynaptic active zone membrane)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006011(Syntaxin, N-terminal)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|interpro:IPR015708(Syntaxin-3)|mint:Q8N4C7	go:"GO:0000920"(septum digestion after cytokinesis)|go:"GO:0003729"(mRNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030686"(90S preribosome)|go:"GO:0032040"(small-subunit processome)|go:"GO:0034388"(Pwp2p-containing subcomplex of 90S preribosome)|interpro:IPR001680(WD40 repeat)|interpro:IPR007148(Small-subunit processome, Utp12)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR027145|interpro:IPR036322|rcsb pdb:5I2T|rcsb pdb:5WLC|rcsb pdb:5WYJ|ensemblfungi:YCR057C(gene)|ensemblfungi:YCR057C_mRNA(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0000447"("endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|rcsb pdb:5WYK|go:"GO:0000472"("endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000480"("endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|rcsb pdb:6KE6|rcsb pdb:6LQP|rcsb pdb:6LQQ|rcsb pdb:6LQR|rcsb pdb:6LQS|rcsb pdb:6LQT|rcsb pdb:6LQU|rcsb pdb:6LQV|rcsb pdb:6ND4|rcsb pdb:6ZQA|rcsb pdb:6ZQB|rcsb pdb:6ZQC|rcsb pdb:6ZQD|rcsb pdb:6ZQE|rcsb pdb:6ZQF|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-6791226|refseq:NP_009984.1|sgd:S000000653|mint:P25635|dip:DIP-1868N	-	comment:mint|comment:homomint	crc64:CBEE4720F81378B6	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:FNBoXbeKnFcWR1+dwnaJVvWJ23c9606	rogid:3JKhaE50yPlCymnkEC14JB9atNY559292	intact-crc:3CAECDD38C0393D5|rigid:8Xnxl0XOXaN/+rHr2sdkkqDMemY	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8N684-3	uniprotkb:P20081	intact:EBI-11523759|ensembl:ENSP00000345412	intact:EBI-6961|uniprotkb:D6W147|ensemblfungi:YNL135C	psi-mi:q8n684-3(display_long)|uniprotkb:Cleavage factor Im complex 59 kDa subunit(gene name synonym)|uniprotkb:CPSF7(gene name)|psi-mi:CPSF7(display_short)|uniprotkb:Cleavage and polyadenylation specificity factor 59 kDa subunit(gene name synonym)|uniprotkb:Pre-mRNA cleavage factor Im 59 kDa subunit(gene name synonym)	psi-mi:fkbp_yeast(display_long)|uniprotkb:RBP1(gene name synonym)|uniprotkb:N1213(orf name)|uniprotkb:N1845(orf name)|uniprotkb:YNL135C(locus name)|uniprotkb:FPR1(gene name)|psi-mi:FPR1(display_short)|uniprotkb:FKB1(gene name synonym)|uniprotkb:Peptidyl-prolyl cis-trans isomerase(gene name synonym)|uniprotkb:Rapamycin-binding protein(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552376|imex:IM-24995-3665	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-746909(isoform-parent)|ensembl:ENSG00000149532(gene)|ensembl:ENST00000340437(transcript)|uniprotkb:Q8N684-3(isoform-parent)	refseq:NP_014264.1|sgd:S000005079|dip:DIP-1263N|mint:P20081|ensemblfungi:YNL135C(gene)|ensemblfungi:YNL135C_mRNA(transcript)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005527"(macrolide binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006325"(chromatin organization)|go:"GO:0006457"(protein folding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:1901710"(regulation of homoserine biosynthetic process)|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)|rcsb pdb:1YAT	-	-	crc64:65C134830D300C06	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:hnk6o9HBKsdIRWKRuEdjdByVKxM9606	rogid:8afvGSk+mPghtqkVoWd2rHJXXhQ559292	intact-crc:4C21AAFC061F139E|rigid:eeeSKW6VR6Te456svsfGznIKuDY	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P39996	uniprotkb:Q8N6G5	intact:EBI-22308|uniprotkb:D3DLN3|ensemblfungi:YEL017W	intact:EBI-10267100|uniprotkb:Q9P1I6|uniprotkb:Q6MZJ5|uniprotkb:B3KWL7|uniprotkb:Q8TCH4|uniprotkb:Q6MZP6|ensembl:ENSP00000363590	psi-mi:gtt3_yeast(display_long)|uniprotkb:GTT3(gene name)|psi-mi:GTT3(display_short)|uniprotkb:YEL017W(locus name)	psi-mi:cgat2_human(display_long)|uniprotkb:CSGALNACT2(gene name)|psi-mi:CSGALNACT2(display_short)|uniprotkb:CHGN2(gene name synonym)|uniprotkb:Chondroitin beta-1,4-N-acetylgalactosaminyltransferase 2(gene name synonym)|uniprotkb:GALNACT2(gene name synonym)|uniprotkb:PRO0082(orf name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552380|imex:IM-24995-3666	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000000743|refseq:NP_010899.3|dip:DIP-2062N|mint:P39996|ensemblfungi:YEL017W(gene)|ensemblfungi:YEL017W_mRNA(transcript)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034399"(nuclear periphery)|interpro:IPR038872	refseq:NP_061060.3|ensembl:ENSG00000169826(gene)|ensembl:ENST00000374466(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0008376"(acetylgalactosaminyltransferase activity)|go:"GO:0016020"(membrane)|go:"GO:0030166"(proteoglycan biosynthetic process)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0030206"(chondroitin sulfate biosynthetic process)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0047237"(glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity)|go:"GO:0047238"(glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity)|go:"GO:0050650"(chondroitin sulfate proteoglycan biosynthetic process)|go:"GO:0050651"(dermatan sulfate proteoglycan biosynthetic process)|go:"GO:0050652"(dermatan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process)|go:"GO:0050653"(chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process)|interpro:IPR008428(Chondroitin N-acetylgalactosaminyltransferase)|interpro:IPR029044|reactome:R-HSA-2022870|refseq:NP_001306583.1|refseq:NP_001306585.1	-	crc64:E9F07EFD2A522006	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:YxznRNPatBf8VkhVPwSCfB5pCDU559292	rogid:uK24H440Kn7+cnVc8C+3dV4SXw89606	intact-crc:55B4E31D997D6DA0|rigid:gWMsutxXJu4ebSSQXUfh46BadP0	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8N684-3	uniprotkb:P20053	intact:EBI-11523759|ensembl:ENSP00000345412	intact:EBI-219|uniprotkb:D6W4H8|ensemblfungi:YPR178W	psi-mi:q8n684-3(display_long)|uniprotkb:Cleavage factor Im complex 59 kDa subunit(gene name synonym)|uniprotkb:CPSF7(gene name)|psi-mi:CPSF7(display_short)|uniprotkb:Cleavage and polyadenylation specificity factor 59 kDa subunit(gene name synonym)|uniprotkb:Pre-mRNA cleavage factor Im 59 kDa subunit(gene name synonym)	psi-mi:prp4_yeast(display_long)|uniprotkb:PRP4(gene name)|psi-mi:PRP4(display_short)|uniprotkb:RNA4(gene name synonym)|uniprotkb:YPR178W(locus name)|uniprotkb:P9705.6(orf name)|uniprotkb:Pre-mRNA-processing protein 4(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552368|imex:IM-24995-3663	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-746909(isoform-parent)|ensembl:ENSG00000149532(gene)|ensembl:ENST00000340437(transcript)|uniprotkb:Q8N684-3(isoform-parent)	refseq:NP_015504.1|sgd:S000006382|mint:P20053|dip:DIP-2607N|ensemblfungi:YPR178W(gene)|ensemblfungi:YPR178W_mRNA(transcript)|go:"GO:0000393"(spliceosomal conformational changes to generate catalytic conformation)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0030621"(U4 snRNA binding)|go:"GO:0034247"(snoRNA splicing)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR014906("Pre-mRNA processing factor 4 (PRP4) like")|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|rcsb pdb:3JCM|rcsb pdb:5GAN|rcsb pdb:5GAP|rcsb pdb:5NRL|rcsb pdb:5ZWM|rcsb pdb:5ZWO	-	-	crc64:7CCCA3A92AC0CE78	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:hnk6o9HBKsdIRWKRuEdjdByVKxM9606	rogid:vvz5G0rqqyrugTvAPelDKit9FpQ559292	intact-crc:E9BDEA4832C086ED|rigid:5QtYmVwYNwdsIJirXMxzEGeQUeU	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8N684-3	uniprotkb:P40956	intact:EBI-11523759|ensembl:ENSP00000345412	intact:EBI-7968|uniprotkb:D6VTX2|ensemblfungi:YGL181W	psi-mi:q8n684-3(display_long)|uniprotkb:Cleavage factor Im complex 59 kDa subunit(gene name synonym)|uniprotkb:CPSF7(gene name)|psi-mi:CPSF7(display_short)|uniprotkb:Cleavage and polyadenylation specificity factor 59 kDa subunit(gene name synonym)|uniprotkb:Pre-mRNA cleavage factor Im 59 kDa subunit(gene name synonym)	psi-mi:gts1_yeast(display_long)|uniprotkb:YGL181W(locus name)|uniprotkb:GTS1(gene name)|psi-mi:GTS1(display_short)|uniprotkb:LSR1(gene name synonym)|uniprotkb:Protein LSR1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552372|imex:IM-24995-3664	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-746909(isoform-parent)|ensembl:ENSG00000149532(gene)|ensembl:ENST00000340437(transcript)|uniprotkb:Q8N684-3(isoform-parent)	refseq:NP_011334.1|sgd:S000003149|mint:P40956|dip:DIP-2746N|ensemblfungi:YGL181W(gene)|ensemblfungi:YGL181W_mRNA(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0006897"(endocytosis)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010512"(negative regulation of phosphatidylinositol biosynthetic process)|go:"GO:0030479"(actin cortical patch)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR037278|interpro:IPR038508	-	-	crc64:D687E3BF6B620795	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:hnk6o9HBKsdIRWKRuEdjdByVKxM9606	rogid:8kgpssCRrHiTHsFaOH2nDK6EIjk559292	intact-crc:D774E28E89690D72|rigid:vh7qvcU5v39+DjimLgDnPocm+bE	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P0CD91	uniprotkb:Q8N6L0	intact:EBI-3820350|uniprotkb:O74680|uniprotkb:P53386|uniprotkb:D6W4J2|ensemblfungi:YPR192W	intact:EBI-749265|uniprotkb:Q96MC3|ensembl:ENSP00000404220	psi-mi:aqy1_yeast(display_long)|uniprotkb:AQY1(gene name)|psi-mi:AQY1(display_short)|uniprotkb:AQY1-2(gene name synonym)|uniprotkb:P9677.5(orf name)|uniprotkb:YPR192W(locus name)	psi-mi:kash5_human(display_long)|uniprotkb:KASH5(gene name)|psi-mi:KASH5(display_short)|uniprotkb:CCDC155(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 155(gene name synonym)|uniprotkb:KASH domain-containing protein 5(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552392|imex:IM-24995-3669	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR034294|refseq:NP_015518.1|sgd:S000006396|interpro:IPR023271|interpro:IPR000425(Major intrinsic protein)|interpro:IPR022357|ensemblfungi:YPR192W(gene)|ensemblfungi:YPR192W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006833"(water transport)|go:"GO:0015250"(water channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030437"(ascospore formation)|go:"GO:0055085"(transmembrane transport)	refseq:NP_653289.3|ensembl:ENSG00000161609(gene)|ensembl:ENST00000447857(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034397"(telomere localization)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051225"(spindle assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0090172"(microtubule cytoskeleton organization involved in homologous chromosome segregation)|go:"GO:0090220"(chromosome localization to nuclear envelope involved in homologous chromosome segregation)|go:"GO:0090619"(meiotic spindle pole)|interpro:IPR011992(EF-Hand type)|interpro:IPR028168|interpro:IPR028170|interpro:IPR039508|mint:Q8N6L0|rcsb pdb:6R2I|rcsb pdb:6WMF	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:SJZXHf9xXd6KcuK51HURax8JgsY559292	rogid:Wl9L7AcvDHCZuKjYLn8QgGIbZTc9606	intact-crc:F738CFB67609FE2E|rigid:nKqk8JDYCD82tNVDhnNg9XNSiyA	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P36019	uniprotkb:Q8N612	intact:EBI-29415|uniprotkb:Q45TZ5|uniprotkb:D6W187|ensemblfungi:YNL093W	intact:EBI-742137|uniprotkb:Q9C0A4|uniprotkb:Q9H0N3|uniprotkb:Q9H624|intact:EBI-28987623|ensembl:ENSP00000416918	psi-mi:ypt53_yeast(display_long)|uniprotkb:YPT53(gene name)|psi-mi:YPT53(display_short)|uniprotkb:N2223(orf name)|uniprotkb:YNL093W(locus name)	psi-mi:fhi1b_human(display_long)|uniprotkb:FHIP1B(gene name)|psi-mi:FHIP1B(display_short)|uniprotkb:C11orf56(gene name synonym)|uniprotkb:FAM160A2(gene name synonym)|uniprotkb:FTS and Hook-interacting protein(gene name synonym)|uniprotkb:KIAA1759(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552364|imex:IM-24995-3662	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005037|refseq:NP_014306.3|dip:DIP-2025N|ensemblfungi:YNL093W(gene)|ensemblfungi:YNL093W_mRNA(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0006897"(endocytosis)|go:"GO:0012505"(endomembrane system)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417	refseq:NP_001092264.1|refseq:NP_115503.2|refseq:XP_011518699.1|ensembl:ENST00000265978|ensembl:ENSP00000265978|ensembl:ENSP00000416918|refseq:XP_006718406.1|ensembl:ENSG00000051009(gene)|ensembl:ENST00000449352(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0007032"(endosome organization)|go:"GO:0007040"(lysosome organization)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0015031"(protein transport)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0070695"(FHF complex)|go:"GO:1905719"(protein localization to perinuclear region of cytoplasm)|interpro:IPR019384	-	crc64:ABA1D926D1EE9F68	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:2IDdF9ESvaxekyjmAzuRL9vMYJ8559292	rogid:sHMptILNXi94k81XAjE55r829C49606	intact-crc:9864ECF15CD9FF72|rigid:LJcwCYkDrCltO+woa97BRuKD/8U	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q12431	uniprotkb:Q8N6L0	intact:EBI-2345238|uniprotkb:D6VXY8|ensemblfungi:YLL014W	intact:EBI-749265|uniprotkb:Q96MC3|ensembl:ENSP00000404220	psi-mi:emc6_yeast(display_long)|uniprotkb:L1321(orf name)|uniprotkb:YLL014W(locus name)|uniprotkb:EMC6(gene name)|psi-mi:EMC6(display_short)	psi-mi:kash5_human(display_long)|uniprotkb:KASH5(gene name)|psi-mi:KASH5(display_short)|uniprotkb:CCDC155(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 155(gene name synonym)|uniprotkb:KASH domain-containing protein 5(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552432|imex:IM-24995-3679	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003937|refseq:NP_013087.1|dip:DIP-988N|ensemblfungi:YLL014W(gene)|ensemblfungi:YLL014W_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0072546"(EMC complex)|interpro:IPR029008|rcsb pdb:6WB9|rcsb pdb:7KRA|rcsb pdb:7KTX	refseq:NP_653289.3|ensembl:ENSG00000161609(gene)|ensembl:ENST00000447857(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034397"(telomere localization)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051225"(spindle assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0090172"(microtubule cytoskeleton organization involved in homologous chromosome segregation)|go:"GO:0090220"(chromosome localization to nuclear envelope involved in homologous chromosome segregation)|go:"GO:0090619"(meiotic spindle pole)|interpro:IPR011992(EF-Hand type)|interpro:IPR028168|interpro:IPR028170|interpro:IPR039508|mint:Q8N6L0|rcsb pdb:6R2I|rcsb pdb:6WMF	-	crc64:36C316F18156823E	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:eDM+DjV86zLNJ9eE07m60y7HWSI559292	rogid:Wl9L7AcvDHCZuKjYLn8QgGIbZTc9606	intact-crc:43461BDA51645A15|rigid:YiShuBqvKw76aSAZ7VNzTxqvKJI	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q08144	uniprotkb:Q8N6L0	intact:EBI-19302|uniprotkb:D6W248|uniprotkb:E9P933|ensemblfungi:YOL018C	intact:EBI-749265|uniprotkb:Q96MC3|ensembl:ENSP00000404220	psi-mi:tlg2_yeast(display_long)|uniprotkb:YOL018C(locus name)|uniprotkb:TLG2(gene name)|psi-mi:TLG2(display_short)|uniprotkb:Syntaxin TLG2(gene name synonym)	psi-mi:kash5_human(display_long)|uniprotkb:KASH5(gene name)|psi-mi:KASH5(display_short)|uniprotkb:CCDC155(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 155(gene name synonym)|uniprotkb:KASH domain-containing protein 5(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552428|imex:IM-24995-3678	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014624.1|sgd:S000005378|ensemblfungi:YOL018C(gene)|ensemblfungi:YOL018C_mRNA(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006673"(inositol phosphoceramide metabolic process)|go:"GO:0006675"(mannosyl-inositol phosphorylceramide metabolic process)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0031303"(integral component of endosome membrane)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0032527"(protein exit from endoplasmic reticulum)|go:"GO:0048278"(vesicle docking)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|interpro:IPR028673|reactome:R-SCE-6811440|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0006897"(endocytosis)|go:"GO:0006906"(vesicle fusion)|go:"GO:0009306"(protein secretion)|dip:DIP-4244N|mint:Q08144	refseq:NP_653289.3|ensembl:ENSG00000161609(gene)|ensembl:ENST00000447857(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034397"(telomere localization)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051225"(spindle assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0090172"(microtubule cytoskeleton organization involved in homologous chromosome segregation)|go:"GO:0090220"(chromosome localization to nuclear envelope involved in homologous chromosome segregation)|go:"GO:0090619"(meiotic spindle pole)|interpro:IPR011992(EF-Hand type)|interpro:IPR028168|interpro:IPR028170|interpro:IPR039508|mint:Q8N6L0|rcsb pdb:6R2I|rcsb pdb:6WMF	-	crc64:CEBD6FE11278B1F0	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:M7Ezt/D1lvPf/T8TrjQwtKNhFhw559292	rogid:Wl9L7AcvDHCZuKjYLn8QgGIbZTc9606	intact-crc:33175C7F03447C68|rigid:7rwn6m3XKT9W7TGcSkZG80H+Vtc	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q03714	uniprotkb:Q8N6L0	intact:EBI-27760|uniprotkb:D6VZE5|ensemblfungi:YML029W	intact:EBI-749265|uniprotkb:Q96MC3|ensembl:ENSP00000404220	psi-mi:usa1_yeast(display_long)|uniprotkb:USA1(gene name)|psi-mi:USA1(display_short)|uniprotkb:YML029W(locus name)	psi-mi:kash5_human(display_long)|uniprotkb:KASH5(gene name)|psi-mi:KASH5(display_short)|uniprotkb:CCDC155(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 155(gene name synonym)|uniprotkb:KASH domain-containing protein 5(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552424|imex:IM-24995-3677	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013683.1|sgd:S000004491|dip:DIP-6423N|mint:Q03714|ensemblfungi:YML029W(gene)|ensemblfungi:YML029W_mRNA(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:1902499"(positive regulation of protein autoubiquitination)|interpro:IPR000626(Ubiquitin)|interpro:IPR029071|rcsb pdb:6VJZ|rcsb pdb:6VK0	refseq:NP_653289.3|ensembl:ENSG00000161609(gene)|ensembl:ENST00000447857(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034397"(telomere localization)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051225"(spindle assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0090172"(microtubule cytoskeleton organization involved in homologous chromosome segregation)|go:"GO:0090220"(chromosome localization to nuclear envelope involved in homologous chromosome segregation)|go:"GO:0090619"(meiotic spindle pole)|interpro:IPR011992(EF-Hand type)|interpro:IPR028168|interpro:IPR028170|interpro:IPR039508|mint:Q8N6L0|rcsb pdb:6R2I|rcsb pdb:6WMF	-	crc64:9B93ECA6C5421FD6	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:k5/W6R8NnkOWchVSQSoXCbvaAZ8559292	rogid:Wl9L7AcvDHCZuKjYLn8QgGIbZTc9606	intact-crc:06AA18F34E769F51|rigid:CfZ0q15whvyngzr6nXKsflD12lg	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8N6L0	uniprotkb:Q12746	intact:EBI-749265|uniprotkb:Q96MC3|ensembl:ENSP00000404220	intact:EBI-27973|uniprotkb:D6W0G0|ensemblfungi:YML125C	psi-mi:kash5_human(display_long)|uniprotkb:KASH5(gene name)|psi-mi:KASH5(display_short)|uniprotkb:CCDC155(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 155(gene name synonym)|uniprotkb:KASH domain-containing protein 5(gene name synonym)	psi-mi:pga3_yeast(display_long)|uniprotkb:YML125C(locus name)|uniprotkb:YM4987.10C(orf name)|uniprotkb:YM7056.01C(orf name)|uniprotkb:PGA3(gene name)|psi-mi:PGA3(display_short)|uniprotkb:NQR1(gene name synonym)|uniprotkb:Processing of GAS1 and ALP protein 3(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552420|imex:IM-24995-3676	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_653289.3|ensembl:ENSG00000161609(gene)|ensembl:ENST00000447857(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034397"(telomere localization)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051225"(spindle assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0090172"(microtubule cytoskeleton organization involved in homologous chromosome segregation)|go:"GO:0090220"(chromosome localization to nuclear envelope involved in homologous chromosome segregation)|go:"GO:0090619"(meiotic spindle pole)|interpro:IPR011992(EF-Hand type)|interpro:IPR028168|interpro:IPR028170|interpro:IPR039508|mint:Q8N6L0|rcsb pdb:6R2I|rcsb pdb:6WMF	refseq:NP_013581.1|sgd:S000004594|dip:DIP-4519N|ensemblfungi:YML125C(gene)|ensemblfungi:YML125C_mRNA(transcript)|go:"GO:0004128"("cytochrome-b5 reductase activity, acting on NAD(P)H")|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|interpro:IPR001433("Oxidoreductase FAD/NAD(P)-binding")|interpro:IPR001709(Flavoprotein pyridine nucleotide cytochrome reductase)|interpro:IPR001834("NADH:cytochrome b5 reductase (CBR)")|interpro:IPR008333(Oxidoreductase FAD-binding region)|interpro:IPR017927|interpro:IPR017938|interpro:IPR039261	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:Wl9L7AcvDHCZuKjYLn8QgGIbZTc9606	rogid:+YTQtKGq+TXHYomne3IHzSiugt4559292	intact-crc:FA7D51C558F2DE7C|rigid:ATjn9y8MMQnYHvcrAnCXMwya3cI	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P38084	uniprotkb:Q8N6L0	intact:EBI-3414|uniprotkb:D6VQ67|ensemblfungi:YBR068C	intact:EBI-749265|uniprotkb:Q96MC3|ensembl:ENSP00000404220	psi-mi:bap2_yeast(display_long)|uniprotkb:Branched-chain amino-acid permease 2(gene name synonym)|uniprotkb:BAP2(gene name)|psi-mi:BAP2(display_short)|uniprotkb:YBR068C(locus name)|uniprotkb:YBR0629(orf name)	psi-mi:kash5_human(display_long)|uniprotkb:KASH5(gene name)|psi-mi:KASH5(display_short)|uniprotkb:CCDC155(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 155(gene name synonym)|uniprotkb:KASH domain-containing protein 5(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552416|imex:IM-24995-3675	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000000272|refseq:NP_009624.4|dip:DIP-4910N|mint:P38084|ensemblfungi:YBR068C(gene)|ensemblfungi:YBR068C_mRNA(transcript)|go:"GO:0003333"(amino acid transmembrane transport)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006865"(amino acid transport)|go:"GO:0015171"(amino acid transmembrane transporter activity)|go:"GO:0015192"(L-phenylalanine transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0055085"(transmembrane transport)|go:"GO:0098713"(leucine import across plasma membrane)|interpro:IPR004762(Amino acid permease, fungi)|interpro:IPR004840(Amino acid permease, conserved site)|interpro:IPR004841(Amino acid permease-associated region)	refseq:NP_653289.3|ensembl:ENSG00000161609(gene)|ensembl:ENST00000447857(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034397"(telomere localization)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051225"(spindle assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0090172"(microtubule cytoskeleton organization involved in homologous chromosome segregation)|go:"GO:0090220"(chromosome localization to nuclear envelope involved in homologous chromosome segregation)|go:"GO:0090619"(meiotic spindle pole)|interpro:IPR011992(EF-Hand type)|interpro:IPR028168|interpro:IPR028170|interpro:IPR039508|mint:Q8N6L0|rcsb pdb:6R2I|rcsb pdb:6WMF	-	crc64:B87FD6A7464E07F5	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:7Fw7+M5mBikZBztHE2tSDpvBi/M559292	rogid:Wl9L7AcvDHCZuKjYLn8QgGIbZTc9606	intact-crc:10B21AB1E17E517F|rigid:06KZtVfu+Zg0jAEL0cOjOPGPNAI	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8N6L0	uniprotkb:P35179	intact:EBI-749265|uniprotkb:Q96MC3|ensembl:ENSP00000404220	intact:EBI-16406|ensemblfungi:YDR086C|uniprotkb:D6VS73	psi-mi:kash5_human(display_long)|uniprotkb:KASH5(gene name)|psi-mi:KASH5(display_short)|uniprotkb:CCDC155(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 155(gene name synonym)|uniprotkb:KASH domain-containing protein 5(gene name synonym)	psi-mi:sc61g_yeast(display_long)|uniprotkb:Sec61 complex subunit SSS1(gene name synonym)|uniprotkb:Ssh1 complex subunit SSS1(gene name synonym)|uniprotkb:D4475(orf name)|uniprotkb:YDR086C(locus name)|uniprotkb:SSS1(gene name)|psi-mi:SSS1(display_short)|uniprotkb:Sec61 complex subunit gamma(gene name synonym)|uniprotkb:Ssh1 complex subunit gamma(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552412|imex:IM-24995-3674	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_653289.3|ensembl:ENSG00000161609(gene)|ensembl:ENST00000447857(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034397"(telomere localization)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051225"(spindle assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0090172"(microtubule cytoskeleton organization involved in homologous chromosome segregation)|go:"GO:0090220"(chromosome localization to nuclear envelope involved in homologous chromosome segregation)|go:"GO:0090619"(meiotic spindle pole)|interpro:IPR011992(EF-Hand type)|interpro:IPR028168|interpro:IPR028170|interpro:IPR039508|mint:Q8N6L0|rcsb pdb:6R2I|rcsb pdb:6WMF	ensemblfungi:YDR086C(gene)|ensemblfungi:YDR086C_mRNA(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0015450"(protein-transporting ATPase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0071261"(Ssh1 translocon complex)|interpro:IPR001901(Protein secE/sec61-gamma protein)|interpro:IPR008158(Protein translocase SEC61 complex gamma subunit)|interpro:IPR023391|rcsb pdb:2WW9|rcsb pdb:2WWA|rcsb pdb:6N3Q|rcsb pdb:6ND1|rcsb pdb:7AFT|rcsb pdb:7KAH|rcsb pdb:7KAI|rcsb pdb:7KAJ|rcsb pdb:7KAO|rcsb pdb:7KAP|rcsb pdb:7KAQ|rcsb pdb:7KAR|rcsb pdb:7KAS|rcsb pdb:7KAT|rcsb pdb:7KAU|rcsb pdb:7KB5|reactome:R-SCE-9609523|refseq:NP_010371.1|sgd:S000002493|dip:DIP-2432N|mint:P35179	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:Wl9L7AcvDHCZuKjYLn8QgGIbZTc9606	rogid:QIi5kN/8mDxTSvxRiJVi2JsPdws559292	intact-crc:C9DF49EE203466E7|rigid:psdiHjU6yqzLy7znfHlfC8W4pSM	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P12945	uniprotkb:Q8N6L0	intact:EBI-11868|ensemblfungi:YDL040C|uniprotkb:D6VRV5	intact:EBI-749265|uniprotkb:Q96MC3|ensembl:ENSP00000404220	psi-mi:nat1_yeast(display_long)|uniprotkb:NAT1(gene name)|psi-mi:NAT1(display_short)|uniprotkb:AAA1(gene name synonym)|uniprotkb:YDL040C(locus name)|uniprotkb:D2720(orf name)|uniprotkb:Amino-terminal, alpha-amino, acetyltransferase 1(gene name synonym)	psi-mi:kash5_human(display_long)|uniprotkb:KASH5(gene name)|psi-mi:KASH5(display_short)|uniprotkb:CCDC155(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 155(gene name synonym)|uniprotkb:KASH domain-containing protein 5(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552404|imex:IM-24995-3672	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YDL040C(gene)|ensemblfungi:YDL040C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006474"(N-terminal protein amino acid acetylation)|go:"GO:0017196"(N-terminal peptidyl-methionine acetylation)|go:"GO:0031415"(NatA complex)|go:"GO:0043022"(ribosome binding)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR021183|rcsb pdb:4HNW|rcsb pdb:4HNY|rcsb pdb:4XNH|rcsb pdb:4XPD|rcsb pdb:4Y49|rcsb pdb:6HD5|rcsb pdb:6HD7|rcsb pdb:6O07|refseq:NP_010244.1|sgd:S000002198|dip:DIP-6329N|mint:P12945	refseq:NP_653289.3|ensembl:ENSG00000161609(gene)|ensembl:ENST00000447857(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034397"(telomere localization)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051225"(spindle assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0090172"(microtubule cytoskeleton organization involved in homologous chromosome segregation)|go:"GO:0090220"(chromosome localization to nuclear envelope involved in homologous chromosome segregation)|go:"GO:0090619"(meiotic spindle pole)|interpro:IPR011992(EF-Hand type)|interpro:IPR028168|interpro:IPR028170|interpro:IPR039508|mint:Q8N6L0|rcsb pdb:6R2I|rcsb pdb:6WMF	-	crc64:DCFB870D049F91E6	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:uzbL/wNoQ9nAcZzglVrbI4GKzOg559292	rogid:Wl9L7AcvDHCZuKjYLn8QgGIbZTc9606	intact-crc:3D234E594A4F525D|rigid:arqSMYQnLNdGXT0Ig8HGi8iPt2c	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8N6L0	uniprotkb:P38842	intact:EBI-749265|uniprotkb:Q96MC3|ensembl:ENSP00000404220	intact:EBI-24752|uniprotkb:D3DL89|uniprotkb:Q6B2K3|ensemblfungi:YHR140W	psi-mi:kash5_human(display_long)|uniprotkb:KASH5(gene name)|psi-mi:KASH5(display_short)|uniprotkb:CCDC155(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 155(gene name synonym)|uniprotkb:KASH domain-containing protein 5(gene name synonym)	psi-mi:yhu0_yeast(display_long)|uniprotkb:YHR140W(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552400|imex:IM-24995-3671	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_653289.3|ensembl:ENSG00000161609(gene)|ensembl:ENST00000447857(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034397"(telomere localization)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051225"(spindle assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0090172"(microtubule cytoskeleton organization involved in homologous chromosome segregation)|go:"GO:0090220"(chromosome localization to nuclear envelope involved in homologous chromosome segregation)|go:"GO:0090619"(meiotic spindle pole)|interpro:IPR011992(EF-Hand type)|interpro:IPR028168|interpro:IPR028170|interpro:IPR039508|mint:Q8N6L0|rcsb pdb:6R2I|rcsb pdb:6WMF	refseq:NP_012009.1|sgd:S000001182|dip:DIP-1786N|ensemblfungi:YHR140W(gene)|ensemblfungi:YHR140W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR006838(FAR-17a/AIG1-like protein)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:Wl9L7AcvDHCZuKjYLn8QgGIbZTc9606	rogid:3CroWy45MlZdD8WyMGvawdwQhrs559292	intact-crc:B26BCB7832FDE019|rigid:pFlcWSa+b6rZZSlavQm3DHY7grw	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q03860	uniprotkb:Q8N6L0	intact:EBI-37537|uniprotkb:D6VS87|ensemblfungi:YDR100W	intact:EBI-749265|uniprotkb:Q96MC3|ensembl:ENSP00000404220	psi-mi:tvp15_yeast(display_long)|uniprotkb:YDR100W(locus name)|uniprotkb:TVP15(gene name)|psi-mi:TVP15(display_short)|uniprotkb:TLG2 compartment vesicle protein 15(gene name synonym)|uniprotkb:TLG2-vesicle protein of 15 kDa(gene name synonym)	psi-mi:kash5_human(display_long)|uniprotkb:KASH5(gene name)|psi-mi:KASH5(display_short)|uniprotkb:CCDC155(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 155(gene name synonym)|uniprotkb:KASH domain-containing protein 5(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552396|imex:IM-24995-3670	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002507|refseq:NP_010385.3|dip:DIP-2049N|mint:Q03860|ensemblfungi:YDR100W(gene)|ensemblfungi:YDR100W_mRNA(transcript)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0042802"(identical protein binding)|interpro:IPR013714(COPI associated)	refseq:NP_653289.3|ensembl:ENSG00000161609(gene)|ensembl:ENST00000447857(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034397"(telomere localization)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051225"(spindle assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0090172"(microtubule cytoskeleton organization involved in homologous chromosome segregation)|go:"GO:0090220"(chromosome localization to nuclear envelope involved in homologous chromosome segregation)|go:"GO:0090619"(meiotic spindle pole)|interpro:IPR011992(EF-Hand type)|interpro:IPR028168|interpro:IPR028170|interpro:IPR039508|mint:Q8N6L0|rcsb pdb:6R2I|rcsb pdb:6WMF	-	crc64:395F700FBB14C569	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:WUrBFK6BrbdV4tMhayDYqINQ5FM559292	rogid:Wl9L7AcvDHCZuKjYLn8QgGIbZTc9606	intact-crc:6E4BC89DAFA1989A|rigid:fuv98/dOVC/xa5CEB2tu0K6VsSg	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8N6L0	uniprotkb:P38206	intact:EBI-749265|uniprotkb:Q96MC3|ensembl:ENSP00000404220	intact:EBI-15028|uniprotkb:Q05814|uniprotkb:D6VPY0|ensemblfungi:YBL020W	psi-mi:kash5_human(display_long)|uniprotkb:KASH5(gene name)|psi-mi:KASH5(display_short)|uniprotkb:CCDC155(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 155(gene name synonym)|uniprotkb:KASH domain-containing protein 5(gene name synonym)	psi-mi:rft1_yeast(display_long)|uniprotkb:RFT1(gene name)|psi-mi:RFT1(display_short)|uniprotkb:YBL020W(locus name)|uniprotkb:YBL0442(orf name)|uniprotkb:Requiring fifty-three protein 1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552408|imex:IM-24995-3673	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_653289.3|ensembl:ENSG00000161609(gene)|ensembl:ENST00000447857(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034397"(telomere localization)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051225"(spindle assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0090172"(microtubule cytoskeleton organization involved in homologous chromosome segregation)|go:"GO:0090220"(chromosome localization to nuclear envelope involved in homologous chromosome segregation)|go:"GO:0090619"(meiotic spindle pole)|interpro:IPR011992(EF-Hand type)|interpro:IPR028168|interpro:IPR028170|interpro:IPR039508|mint:Q8N6L0|rcsb pdb:6R2I|rcsb pdb:6WMF	refseq:NP_009533.1|sgd:S000000116|ensemblfungi:YBL020W(gene)|ensemblfungi:YBL020W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006488"(dolichol-linked oligosaccharide biosynthetic process)|go:"GO:0008643"(carbohydrate transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034202"(glycolipid floppase activity)|go:"GO:0034203"(glycolipid translocation)|interpro:IPR007594(RFT1)|dip:DIP-3885N|mint:P38206	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:Wl9L7AcvDHCZuKjYLn8QgGIbZTc9606	rogid:nBfsGoVh81NwPryblR48jOVVQsU559292	intact-crc:593D1A5D41359025|rigid:+mKcNMiv2h/xD/MRZ7N4T/Iqe50	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P40567	uniprotkb:Q8N6L0	intact:EBI-789|uniprotkb:D6VVT9|ensemblfungi:YIR009W	intact:EBI-749265|uniprotkb:Q96MC3|ensembl:ENSP00000404220	psi-mi:msl1_yeast(display_long)|uniprotkb:YIB9W(orf name)|uniprotkb:YIR009W(locus name)|uniprotkb:MSL1(gene name)|psi-mi:MSL1(display_short)	psi-mi:kash5_human(display_long)|uniprotkb:KASH5(gene name)|psi-mi:KASH5(display_short)|uniprotkb:CCDC155(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 155(gene name synonym)|uniprotkb:KASH domain-containing protein 5(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552460|imex:IM-24995-3686	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012274.1|sgd:S000001448|rcsb pdb:6BK8|ensemblfungi:YIR009W(gene)|ensemblfungi:YIR009W_mRNA(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005685"(U1 snRNP)|go:"GO:0030619"(U1 snRNA binding)|go:"GO:0030620"(U2 snRNA binding)|go:"GO:0071004"(U2-type prespliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5MQ0|rcsb pdb:5NRL|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:5ZWM|rcsb pdb:5ZWO|dip:DIP-816N|mint:P40567|rcsb pdb:6EXN|rcsb pdb:6G90|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q	refseq:NP_653289.3|ensembl:ENSG00000161609(gene)|ensembl:ENST00000447857(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034397"(telomere localization)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051225"(spindle assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0090172"(microtubule cytoskeleton organization involved in homologous chromosome segregation)|go:"GO:0090220"(chromosome localization to nuclear envelope involved in homologous chromosome segregation)|go:"GO:0090619"(meiotic spindle pole)|interpro:IPR011992(EF-Hand type)|interpro:IPR028168|interpro:IPR028170|interpro:IPR039508|mint:Q8N6L0|rcsb pdb:6R2I|rcsb pdb:6WMF	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:GAiHZKcbfNjbem3+i1cZXFm4NfE559292	rogid:Wl9L7AcvDHCZuKjYLn8QgGIbZTc9606	intact-crc:38E8DB7014086AA2|rigid:n1Ez7t+dqoZQpQT8zY35xI/j6uY	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q02724	uniprotkb:Q8N6L0	intact:EBI-20050|uniprotkb:D6W3Z2|ensemblfungi:YPL020C	intact:EBI-749265|uniprotkb:Q96MC3|ensembl:ENSP00000404220	psi-mi:ulp1_yeast(display_long)|uniprotkb:ULP1(gene name)|psi-mi:ULP1(display_short)|uniprotkb:LPB11C(orf name)|uniprotkb:YPL020C(locus name)	psi-mi:kash5_human(display_long)|uniprotkb:KASH5(gene name)|psi-mi:KASH5(display_short)|uniprotkb:CCDC155(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 155(gene name synonym)|uniprotkb:KASH domain-containing protein 5(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552456|imex:IM-24995-3685	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015305.1|sgd:S000005941|ensemblfungi:YPL020C(gene)|ensemblfungi:YPL020C_mRNA(transcript)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005730"(nucleolus)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0016926"(protein desumoylation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070140"(SUMO-specific isopeptidase activity)|interpro:IPR003653(Peptidase C48, SUMO/Sentrin/Ubl1)|interpro:IPR038765|rcsb pdb:1EUV|rcsb pdb:2HKP|rcsb pdb:2HL8|rcsb pdb:2HL9|rcsb pdb:5H2V|rcsb pdb:5H2W|rcsb pdb:5H2X|reactome:R-SCE-3065679|reactome:R-SCE-6791226|dip:DIP-4041N|mint:Q02724	refseq:NP_653289.3|ensembl:ENSG00000161609(gene)|ensembl:ENST00000447857(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034397"(telomere localization)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051225"(spindle assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0090172"(microtubule cytoskeleton organization involved in homologous chromosome segregation)|go:"GO:0090220"(chromosome localization to nuclear envelope involved in homologous chromosome segregation)|go:"GO:0090619"(meiotic spindle pole)|interpro:IPR011992(EF-Hand type)|interpro:IPR028168|interpro:IPR028170|interpro:IPR039508|mint:Q8N6L0|rcsb pdb:6R2I|rcsb pdb:6WMF	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:H9B4qZf/ZMbHr7u4hbtR4fzz0ec559292	rogid:Wl9L7AcvDHCZuKjYLn8QgGIbZTc9606	intact-crc:C4060301EAD20C3D|rigid:kcJcZoruEPpVCr09h4BbpwgBs2s	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8N6L0	uniprotkb:P38736	intact:EBI-749265|uniprotkb:Q96MC3|ensembl:ENSP00000404220	intact:EBI-24365|uniprotkb:D3DKT7|ensemblfungi:YHL031C	psi-mi:kash5_human(display_long)|uniprotkb:KASH5(gene name)|psi-mi:KASH5(display_short)|uniprotkb:CCDC155(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 155(gene name synonym)|uniprotkb:KASH domain-containing protein 5(gene name synonym)	psi-mi:gosr1_yeast(display_long)|uniprotkb:Golgi SNARE protein 1(gene name synonym)|uniprotkb:GOS1(gene name)|psi-mi:GOS1(display_short)|uniprotkb:Protein transport protein GOS1(gene name synonym)|uniprotkb:YHL031C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552452|imex:IM-24995-3684	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_653289.3|ensembl:ENSG00000161609(gene)|ensembl:ENST00000447857(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034397"(telomere localization)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051225"(spindle assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0090172"(microtubule cytoskeleton organization involved in homologous chromosome segregation)|go:"GO:0090220"(chromosome localization to nuclear envelope involved in homologous chromosome segregation)|go:"GO:0090619"(meiotic spindle pole)|interpro:IPR011992(EF-Hand type)|interpro:IPR028168|interpro:IPR028170|interpro:IPR039508|mint:Q8N6L0|rcsb pdb:6R2I|rcsb pdb:6WMF	refseq:NP_011832.1|sgd:S000001023|reactome:R-SCE-6811438|dip:DIP-2490N|reactome:R-SCE-6807878|ensemblfungi:YHL031C(gene)|ensemblfungi:YHL031C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005797"(Golgi medial cisterna)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0048193"(Golgi vesicle transport)|go:"GO:0048209"(regulation of vesicle targeting, to, from or within Golgi)|interpro:IPR023601|go:"GO:0006906"(vesicle fusion)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:Wl9L7AcvDHCZuKjYLn8QgGIbZTc9606	rogid:pAzDzV46XXzIOB4p/oc1PlMc54E559292	intact-crc:27AF610C4FB7B287|rigid:AwEJ1X9wku/5sYyHJ7+ja3HtWaQ	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P47013	uniprotkb:Q8N6L0	intact:EBI-26081|uniprotkb:D6VW50|ensemblfungi:YJL134W	intact:EBI-749265|uniprotkb:Q96MC3|ensembl:ENSP00000404220	psi-mi:ds1p1_yeast(display_long)|uniprotkb:YJL134W(locus name)|uniprotkb:J0671(orf name)|uniprotkb:LCB3(gene name)|psi-mi:LCB3(display_short)|uniprotkb:LBP1(gene name synonym)|uniprotkb:YSR2(gene name synonym)|uniprotkb:Long-chain base protein 3(gene name synonym)|uniprotkb:Sphingolipid resistance protein 2(gene name synonym)	psi-mi:kash5_human(display_long)|uniprotkb:KASH5(gene name)|psi-mi:KASH5(display_short)|uniprotkb:CCDC155(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 155(gene name synonym)|uniprotkb:KASH domain-containing protein 5(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552448|imex:IM-24995-3683	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012401.1|sgd:S000003670|reactome:R-SCE-1660661|dip:DIP-5685N|ensemblfungi:YJL134W(gene)|ensemblfungi:YJL134W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0042392"(sphingosine-1-phosphate phosphatase activity)|go:"GO:0046839"(phospholipid dephosphorylation)|go:"GO:0070780"(dihydrosphingosine-1-phosphate phosphatase activity)|interpro:IPR000326(Phosphatidic acid phosphatase type 2/haloperoxidase)|interpro:IPR036938	refseq:NP_653289.3|ensembl:ENSG00000161609(gene)|ensembl:ENST00000447857(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034397"(telomere localization)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051225"(spindle assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0090172"(microtubule cytoskeleton organization involved in homologous chromosome segregation)|go:"GO:0090220"(chromosome localization to nuclear envelope involved in homologous chromosome segregation)|go:"GO:0090619"(meiotic spindle pole)|interpro:IPR011992(EF-Hand type)|interpro:IPR028168|interpro:IPR028170|interpro:IPR039508|mint:Q8N6L0|rcsb pdb:6R2I|rcsb pdb:6WMF	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:PY4waY+3MkYSvto7aiARAO5UHzI559292	rogid:Wl9L7AcvDHCZuKjYLn8QgGIbZTc9606	intact-crc:2FEC8A3C194DD4CD|rigid:y76M63Y2OBtRHIjH4BLDQsH9Kqc	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8N6L0	uniprotkb:P28496	intact:EBI-749265|uniprotkb:Q96MC3|ensembl:ENSP00000404220	intact:EBI-26585|uniprotkb:D6VXS8|ensemblfungi:YKL008C	psi-mi:kash5_human(display_long)|uniprotkb:KASH5(gene name)|psi-mi:KASH5(display_short)|uniprotkb:CCDC155(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 155(gene name synonym)|uniprotkb:KASH domain-containing protein 5(gene name synonym)	psi-mi:lac1_yeast(display_long)|uniprotkb:LAC1(gene name)|psi-mi:LAC1(display_short)|uniprotkb:DGT1(gene name synonym)|uniprotkb:Very-long-chain ceramide synthase LAC1(gene name synonym)|uniprotkb:YKL156(orf name)|uniprotkb:YKL008C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552444|imex:IM-24995-3682	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_653289.3|ensembl:ENSG00000161609(gene)|ensembl:ENST00000447857(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034397"(telomere localization)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051225"(spindle assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0090172"(microtubule cytoskeleton organization involved in homologous chromosome segregation)|go:"GO:0090220"(chromosome localization to nuclear envelope involved in homologous chromosome segregation)|go:"GO:0090619"(meiotic spindle pole)|interpro:IPR011992(EF-Hand type)|interpro:IPR028168|interpro:IPR028170|interpro:IPR039508|mint:Q8N6L0|rcsb pdb:6R2I|rcsb pdb:6WMF	sgd:S000001491|refseq:NP_012917.3|mint:P28496|dip:DIP-4348N|ensemblfungi:YKL008C(gene)|ensemblfungi:YKL008C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016410"(N-acyltransferase activity)|go:"GO:0034399"(nuclear periphery)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:0050291"(sphingosine N-acyltransferase activity)|go:"GO:0061576"(acyl-CoA ceramide synthase complex)|interpro:IPR006634(TRAM, LAG1 and CLN8 homology)|interpro:IPR013599(TRAM1-like protein)|interpro:IPR016439(Longevity assurance, LAG1/LAC1)|reactome:R-SCE-1660661	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:Wl9L7AcvDHCZuKjYLn8QgGIbZTc9606	rogid:gqRCCAHQcrRAHNO+R2LkQOzJ0mg559292	intact-crc:996D922BEBA38B7C|rigid:uxF2JNsk6pUSjMh4HBozlamYkDE	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q01590	uniprotkb:Q8N6L0	intact:EBI-16930|uniprotkb:D6VY28|ensemblfungi:YLR026C	intact:EBI-749265|uniprotkb:Q96MC3|ensembl:ENSP00000404220	psi-mi:sed5_yeast(display_long)|uniprotkb:SED5(gene name)|psi-mi:SED5(display_short)|uniprotkb:YLR026C(locus name)	psi-mi:kash5_human(display_long)|uniprotkb:KASH5(gene name)|psi-mi:KASH5(display_short)|uniprotkb:CCDC155(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 155(gene name synonym)|uniprotkb:KASH domain-containing protein 5(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552440|imex:IM-24995-3681	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013126.1|sgd:S000004016|ensemblfungi:YLR026C(gene)|ensemblfungi:YLR026C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0006906"(vesicle fusion)|go:"GO:0090083"(regulation of inclusion body assembly)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|interpro:IPR021538|rcsb pdb:1MQS|rcsb pdb:1PD0|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|reactome:R-SCE-204005|reactome:R-SCE-5694530|reactome:R-SCE-6807878|reactome:R-SCE-6811438|reactome:R-SCE-9609523|go:"GO:0031201"(SNARE complex)|go:"GO:0048278"(vesicle docking)|go:"GO:0048280"(vesicle fusion with Golgi apparatus)|dip:DIP-2489N|mint:Q01590	refseq:NP_653289.3|ensembl:ENSG00000161609(gene)|ensembl:ENST00000447857(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034397"(telomere localization)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051225"(spindle assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0090172"(microtubule cytoskeleton organization involved in homologous chromosome segregation)|go:"GO:0090220"(chromosome localization to nuclear envelope involved in homologous chromosome segregation)|go:"GO:0090619"(meiotic spindle pole)|interpro:IPR011992(EF-Hand type)|interpro:IPR028168|interpro:IPR028170|interpro:IPR039508|mint:Q8N6L0|rcsb pdb:6R2I|rcsb pdb:6WMF	-	crc64:B3192B57269A0B83	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:c+W+86qfjxcvWWJ9nMScyH5TjNA559292	rogid:Wl9L7AcvDHCZuKjYLn8QgGIbZTc9606	intact-crc:D0CC5C4944CCA05D|rigid:Tz4PxmOiFDvWjE8O6ssbXUTVHDA	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q6Q595	uniprotkb:Q8N6L0	intact:EBI-2346131|uniprotkb:D6VPR2|ensemblfungi:YBL091C-A	intact:EBI-749265|uniprotkb:Q96MC3|ensembl:ENSP00000404220	psi-mi:scs22_yeast(display_long)|uniprotkb:SCS22(gene name)|psi-mi:SCS22(display_short)|uniprotkb:VAP homolog 2(gene name synonym)|uniprotkb:YBL091C-A(locus name)	psi-mi:kash5_human(display_long)|uniprotkb:KASH5(gene name)|psi-mi:KASH5(display_short)|uniprotkb:CCDC155(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 155(gene name synonym)|uniprotkb:KASH domain-containing protein 5(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552436|imex:IM-24995-3680	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009461.2|sgd:S000007228|interpro:IPR000535(Major sperm protein)|interpro:IPR008962(PapD-like)|interpro:IPR016763(Vesicle-associated membrane protein)|interpro:IPR013783(Immunoglobulin-like fold)|ensemblfungi:YBL091C-A(gene)|ensemblfungi:YBL091C-A_mRNA(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008654"(phospholipid biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033149"(FFAT motif binding)|go:"GO:0060304"(regulation of phosphatidylinositol dephosphorylation)|go:"GO:0061817"(endoplasmic reticulum-plasma membrane tethering)|go:"GO:0090158"(endoplasmic reticulum membrane organization)	refseq:NP_653289.3|ensembl:ENSG00000161609(gene)|ensembl:ENST00000447857(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034397"(telomere localization)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051225"(spindle assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0090172"(microtubule cytoskeleton organization involved in homologous chromosome segregation)|go:"GO:0090220"(chromosome localization to nuclear envelope involved in homologous chromosome segregation)|go:"GO:0090619"(meiotic spindle pole)|interpro:IPR011992(EF-Hand type)|interpro:IPR028168|interpro:IPR028170|interpro:IPR039508|mint:Q8N6L0|rcsb pdb:6R2I|rcsb pdb:6WMF	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:CEe2fGzBKS+GTm7wv+avSs9DXOU559292	rogid:Wl9L7AcvDHCZuKjYLn8QgGIbZTc9606	intact-crc:F3966B1334ECC0AF|rigid:a3ZZyPKBWZv8lo+SV70dEig6Qc0	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8N6L0	uniprotkb:P46965	intact:EBI-749265|uniprotkb:Q96MC3|ensembl:ENSP00000404220	intact:EBI-17823|uniprotkb:D6VWI6|ensemblfungi:YJR010C-A	psi-mi:kash5_human(display_long)|uniprotkb:KASH5(gene name)|psi-mi:KASH5(display_short)|uniprotkb:CCDC155(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 155(gene name synonym)|uniprotkb:KASH domain-containing protein 5(gene name synonym)	psi-mi:spc1_yeast(display_long)|uniprotkb:SPC1(gene name)|psi-mi:SPC1(display_short)|uniprotkb:YJR010C-A(locus name)|uniprotkb:YJR010BW(orf name)|uniprotkb:Microsomal signal peptidase subunit 1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552468|imex:IM-24995-3688	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_653289.3|ensembl:ENSG00000161609(gene)|ensembl:ENST00000447857(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034397"(telomere localization)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051225"(spindle assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0090172"(microtubule cytoskeleton organization involved in homologous chromosome segregation)|go:"GO:0090220"(chromosome localization to nuclear envelope involved in homologous chromosome segregation)|go:"GO:0090619"(meiotic spindle pole)|interpro:IPR011992(EF-Hand type)|interpro:IPR028168|interpro:IPR028170|interpro:IPR039508|mint:Q8N6L0|rcsb pdb:6R2I|rcsb pdb:6WMF	refseq:NP_012544.1|sgd:S000003770|ensemblfungi:YJR010C-A(gene)|ensemblfungi:YJR010C-A_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005787"(signal peptidase complex)|go:"GO:0006465"(signal peptide processing)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0045047"(protein targeting to ER)|interpro:IPR009542(Microsomal signal peptidase 12 kDa subunit)|interpro:IPR037713|mint:P46965|dip:DIP-2770N	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:Wl9L7AcvDHCZuKjYLn8QgGIbZTc9606	rogid:kchUi3mkadvzweVkrWO3QkbbHew559292	intact-crc:A6FDEA4FD8FB26E5|rigid:q6X7Z1tL2sUDclMaelgwNgDtn90	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8N6L0	uniprotkb:P39996	intact:EBI-749265|uniprotkb:Q96MC3|ensembl:ENSP00000404220	intact:EBI-22308|uniprotkb:D3DLN3|ensemblfungi:YEL017W	psi-mi:kash5_human(display_long)|uniprotkb:KASH5(gene name)|psi-mi:KASH5(display_short)|uniprotkb:CCDC155(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 155(gene name synonym)|uniprotkb:KASH domain-containing protein 5(gene name synonym)	psi-mi:gtt3_yeast(display_long)|uniprotkb:GTT3(gene name)|psi-mi:GTT3(display_short)|uniprotkb:YEL017W(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552472|imex:IM-24995-3689	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_653289.3|ensembl:ENSG00000161609(gene)|ensembl:ENST00000447857(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034397"(telomere localization)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051225"(spindle assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0090172"(microtubule cytoskeleton organization involved in homologous chromosome segregation)|go:"GO:0090220"(chromosome localization to nuclear envelope involved in homologous chromosome segregation)|go:"GO:0090619"(meiotic spindle pole)|interpro:IPR011992(EF-Hand type)|interpro:IPR028168|interpro:IPR028170|interpro:IPR039508|mint:Q8N6L0|rcsb pdb:6R2I|rcsb pdb:6WMF	sgd:S000000743|refseq:NP_010899.3|dip:DIP-2062N|mint:P39996|ensemblfungi:YEL017W(gene)|ensemblfungi:YEL017W_mRNA(transcript)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034399"(nuclear periphery)|interpro:IPR038872	-	-	crc64:E9F07EFD2A522006	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:Wl9L7AcvDHCZuKjYLn8QgGIbZTc9606	rogid:YxznRNPatBf8VkhVPwSCfB5pCDU559292	intact-crc:B843A4E29C199763|rigid:ZOF8n/du+kl3uNplIoAReVMTnjI	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8N6L0	uniprotkb:P40312	intact:EBI-749265|uniprotkb:Q96MC3|ensembl:ENSP00000404220	intact:EBI-2095239|uniprotkb:D6W170|ensemblfungi:YNL111C	psi-mi:kash5_human(display_long)|uniprotkb:KASH5(gene name)|psi-mi:KASH5(display_short)|uniprotkb:CCDC155(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 155(gene name synonym)|uniprotkb:KASH domain-containing protein 5(gene name synonym)	psi-mi:cyb5_yeast(display_long)|uniprotkb:N1949(orf name)|uniprotkb:YNL111C(locus name)|uniprotkb:CYB5(gene name)|psi-mi:CYB5(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552476|imex:IM-24995-3690	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_653289.3|ensembl:ENSG00000161609(gene)|ensembl:ENST00000447857(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034397"(telomere localization)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051225"(spindle assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0090172"(microtubule cytoskeleton organization involved in homologous chromosome segregation)|go:"GO:0090220"(chromosome localization to nuclear envelope involved in homologous chromosome segregation)|go:"GO:0090619"(meiotic spindle pole)|interpro:IPR011992(EF-Hand type)|interpro:IPR028168|interpro:IPR028170|interpro:IPR039508|mint:Q8N6L0|rcsb pdb:6R2I|rcsb pdb:6WMF	sgd:S000005055|interpro:IPR001199(Cytochrome b5)|interpro:IPR018506|refseq:NP_014288.3|mint:P40312|interpro:IPR036400|ensemblfungi:YNL111C(gene)|ensemblfungi:YNL111C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0009055"(electron transfer activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016126"(sterol biosynthetic process)|go:"GO:0020037"(heme binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|reactome:R-SCE-196836|reactome:R-SCE-9609523	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:Wl9L7AcvDHCZuKjYLn8QgGIbZTc9606	rogid:aB5Ul8scxDg0gRGx3rkZwTtfNM4559292	intact-crc:BF41F95BBBF38312|rigid:8eqAa6AQQ/XG1Q8umWLNxw2xuiw	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q04969	uniprotkb:Q8N6L0	intact:EBI-27827|uniprotkb:D6VZB9|ensemblfungi:YML055W	intact:EBI-749265|uniprotkb:Q96MC3|ensembl:ENSP00000404220	psi-mi:spc2_yeast(display_long)|uniprotkb:YML055W(locus name)|uniprotkb:YM9958.07(orf name)|uniprotkb:SPC2(gene name)|psi-mi:SPC2(display_short)|uniprotkb:SPY1(gene name synonym)|uniprotkb:Microsomal signal peptidase subunit 2(gene name synonym)	psi-mi:kash5_human(display_long)|uniprotkb:KASH5(gene name)|psi-mi:KASH5(display_short)|uniprotkb:CCDC155(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 155(gene name synonym)|uniprotkb:KASH domain-containing protein 5(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552480|imex:IM-24995-3691	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013657.1|sgd:S000004519|dip:DIP-4540N|mint:Q04969|ensemblfungi:YML055W(gene)|ensemblfungi:YML055W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005787"(signal peptidase complex)|go:"GO:0006465"(signal peptide processing)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045047"(protein targeting to ER)|go:"GO:0120236"(negative regulation of posttranslational protein targeting to membrane, translocation)|interpro:IPR009582(Microsomal signal peptidase 25 kDa subunit)	refseq:NP_653289.3|ensembl:ENSG00000161609(gene)|ensembl:ENST00000447857(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034397"(telomere localization)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051225"(spindle assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0090172"(microtubule cytoskeleton organization involved in homologous chromosome segregation)|go:"GO:0090220"(chromosome localization to nuclear envelope involved in homologous chromosome segregation)|go:"GO:0090619"(meiotic spindle pole)|interpro:IPR011992(EF-Hand type)|interpro:IPR028168|interpro:IPR028170|interpro:IPR039508|mint:Q8N6L0|rcsb pdb:6R2I|rcsb pdb:6WMF	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:ZXf9rPA3/ryPnDqI4JGp0VMNMe4559292	rogid:Wl9L7AcvDHCZuKjYLn8QgGIbZTc9606	intact-crc:A9FAD1B5C9F34537|rigid:400OZ0VEOZXtLA3t20J6oKxeQQQ	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P40533	uniprotkb:Q8N6L0	intact:EBI-24998|uniprotkb:D6VVP3|ensemblfungi:YIL039W	intact:EBI-749265|uniprotkb:Q96MC3|ensembl:ENSP00000404220	psi-mi:ted1_yeast(display_long)|uniprotkb:TED1(gene name)|psi-mi:TED1(display_short)|uniprotkb:Trafficking of EMP24/ERV25-dependent cargo disrupted protein 1(gene name synonym)|uniprotkb:YIL039W(locus name)	psi-mi:kash5_human(display_long)|uniprotkb:KASH5(gene name)|psi-mi:KASH5(display_short)|uniprotkb:CCDC155(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 155(gene name synonym)|uniprotkb:KASH domain-containing protein 5(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552484|imex:IM-24995-3692	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012225.1|sgd:S000001301|mint:P40533|dip:DIP-4575N|ensemblfungi:YIL039W(gene)|ensemblfungi:YIL039W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006506"(GPI anchor biosynthetic process)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016787"(hydrolase activity)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR029052|interpro:IPR033307|interpro:IPR033308	refseq:NP_653289.3|ensembl:ENSG00000161609(gene)|ensembl:ENST00000447857(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034397"(telomere localization)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051225"(spindle assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0090172"(microtubule cytoskeleton organization involved in homologous chromosome segregation)|go:"GO:0090220"(chromosome localization to nuclear envelope involved in homologous chromosome segregation)|go:"GO:0090619"(meiotic spindle pole)|interpro:IPR011992(EF-Hand type)|interpro:IPR028168|interpro:IPR028170|interpro:IPR039508|mint:Q8N6L0|rcsb pdb:6R2I|rcsb pdb:6WMF	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:/O/7xxWpFv7PwN+keOZRqQQPoFw559292	rogid:Wl9L7AcvDHCZuKjYLn8QgGIbZTc9606	intact-crc:F53631DB276A17EB|rigid:atuyt74ltwZk0Cp4nQBel7EZ7BE	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8N6L0	uniprotkb:P32502	intact:EBI-749265|uniprotkb:Q96MC3|ensembl:ENSP00000404220	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:kash5_human(display_long)|uniprotkb:KASH5(gene name)|psi-mi:KASH5(display_short)|uniprotkb:CCDC155(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 155(gene name synonym)|uniprotkb:KASH domain-containing protein 5(gene name synonym)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552488|imex:IM-24995-3693	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_653289.3|ensembl:ENSG00000161609(gene)|ensembl:ENST00000447857(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034397"(telomere localization)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051225"(spindle assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0090172"(microtubule cytoskeleton organization involved in homologous chromosome segregation)|go:"GO:0090220"(chromosome localization to nuclear envelope involved in homologous chromosome segregation)|go:"GO:0090619"(meiotic spindle pole)|interpro:IPR011992(EF-Hand type)|interpro:IPR028168|interpro:IPR028170|interpro:IPR039508|mint:Q8N6L0|rcsb pdb:6R2I|rcsb pdb:6WMF	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731	-	-	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:Wl9L7AcvDHCZuKjYLn8QgGIbZTc9606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:64889C5C3BB571CA|rigid:2JxAFY6iMFYY2m55YCnuCUYq+lE	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q12118	uniprotkb:Q8N6L0	intact:EBI-31784|uniprotkb:D6W273|ensemblfungi:YOR007C	intact:EBI-749265|uniprotkb:Q96MC3|ensembl:ENSP00000404220	psi-mi:sgt2_yeast(display_long)|uniprotkb:Viral protein U-binding protein(gene name synonym)|uniprotkb:SGT/UBP(gene name synonym)|uniprotkb:SGT2(gene name)|psi-mi:SGT2(display_short)|uniprotkb:UNF346(orf name)|uniprotkb:YOR007C(locus name)	psi-mi:kash5_human(display_long)|uniprotkb:KASH5(gene name)|psi-mi:KASH5(display_short)|uniprotkb:CCDC155(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 155(gene name synonym)|uniprotkb:KASH domain-containing protein 5(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552492|imex:IM-24995-3694	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014649.1|sgd:S000005533|dip:DIP-1983N|mint:Q12118|ensemblfungi:YOR007C(gene)|ensemblfungi:YOR007C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0009408"(response to heat)|go:"GO:0016020"(membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0072380"(TRC complex)|go:"GO:1903646"(positive regulation of chaperone-mediated protein folding)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR032374|rcsb pdb:2LXB|rcsb pdb:2LXC|rcsb pdb:3ZDM|rcsb pdb:4ASV|rcsb pdb:4ASW|rcsb pdb:5LYN|rcsb pdb:5LYP|reactome:R-SCE-9609523	refseq:NP_653289.3|ensembl:ENSG00000161609(gene)|ensembl:ENST00000447857(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034397"(telomere localization)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051225"(spindle assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0090172"(microtubule cytoskeleton organization involved in homologous chromosome segregation)|go:"GO:0090220"(chromosome localization to nuclear envelope involved in homologous chromosome segregation)|go:"GO:0090619"(meiotic spindle pole)|interpro:IPR011992(EF-Hand type)|interpro:IPR028168|interpro:IPR028170|interpro:IPR039508|mint:Q8N6L0|rcsb pdb:6R2I|rcsb pdb:6WMF	-	crc64:33539B74F742BD3C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:u4qztYWJIAVQOzZGnkLFnO3S2NA559292	rogid:Wl9L7AcvDHCZuKjYLn8QgGIbZTc9606	intact-crc:70E7F432CC415539|rigid:oOlfY2RAvw3VKWEdOMZwnytHY8o	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8N6L0	uniprotkb:P38695	intact:EBI-749265|uniprotkb:Q96MC3|ensembl:ENSP00000404220	intact:EBI-8778|ensemblfungi:YHR096C|uniprotkb:D3DL46	psi-mi:kash5_human(display_long)|uniprotkb:KASH5(gene name)|psi-mi:KASH5(display_short)|uniprotkb:CCDC155(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 155(gene name synonym)|uniprotkb:KASH domain-containing protein 5(gene name synonym)	psi-mi:hxt5_yeast(display_long)|uniprotkb:YHR096C(locus name)|uniprotkb:HXT5(gene name)|psi-mi:HXT5(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552464|imex:IM-24995-3687	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_653289.3|ensembl:ENSG00000161609(gene)|ensembl:ENST00000447857(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034397"(telomere localization)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051225"(spindle assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0090172"(microtubule cytoskeleton organization involved in homologous chromosome segregation)|go:"GO:0090220"(chromosome localization to nuclear envelope involved in homologous chromosome segregation)|go:"GO:0090619"(meiotic spindle pole)|interpro:IPR011992(EF-Hand type)|interpro:IPR028168|interpro:IPR028170|interpro:IPR039508|mint:Q8N6L0|rcsb pdb:6R2I|rcsb pdb:6WMF	ensemblfungi:YHR096C(gene)|ensemblfungi:YHR096C_mRNA(transcript)|go:"GO:0005351"("carbohydrate:proton symporter activity")|go:"GO:0005355"(glucose transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005353"(fructose transmembrane transporter activity)|go:"GO:0008643"(carbohydrate transport)|go:"GO:0008645"(hexose transmembrane transport)|go:"GO:0015578"(mannose transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|go:"GO:1904659"(glucose transmembrane transport)|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259|refseq:NP_011964.1|sgd:S000001138|mint:P38695|dip:DIP-5594N	-	-	crc64:6906721BAC1A5F87	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:Wl9L7AcvDHCZuKjYLn8QgGIbZTc9606	rogid:aZGrWmUu+AZ4G6qmTG+Z+p6i7hs559292	intact-crc:6C95BA5339BFBD82|rigid:t8lYMWTXrz7eoxfyij3jYiVMNaM	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P46956	uniprotkb:Q8N6L0	intact:EBI-13337|uniprotkb:E9P8T7|ensemblfungi:YJL117W|uniprotkb:D6VW67	intact:EBI-749265|uniprotkb:Q96MC3|ensembl:ENSP00000404220	psi-mi:pho86_yeast(display_long)|uniprotkb:PHO86(gene name)|psi-mi:PHO86(display_short)|uniprotkb:J0744(orf name)|uniprotkb:YJL117W(locus name)	psi-mi:kash5_human(display_long)|uniprotkb:KASH5(gene name)|psi-mi:KASH5(display_short)|uniprotkb:CCDC155(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 155(gene name synonym)|uniprotkb:KASH domain-containing protein 5(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552504|imex:IM-24995-3697	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012418.1|sgd:S000003653|interpro:IPR024297|ensemblfungi:YJL117W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006457"(protein folding)|go:"GO:0006817"(phosphate ion transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0010966"(regulation of phosphate transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0051082"(unfolded protein binding)|ensemblfungi:YJL117W(gene)|mint:P46956|dip:DIP-2769N	refseq:NP_653289.3|ensembl:ENSG00000161609(gene)|ensembl:ENST00000447857(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034397"(telomere localization)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051225"(spindle assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0090172"(microtubule cytoskeleton organization involved in homologous chromosome segregation)|go:"GO:0090220"(chromosome localization to nuclear envelope involved in homologous chromosome segregation)|go:"GO:0090619"(meiotic spindle pole)|interpro:IPR011992(EF-Hand type)|interpro:IPR028168|interpro:IPR028170|interpro:IPR039508|mint:Q8N6L0|rcsb pdb:6R2I|rcsb pdb:6WMF	-	crc64:1CB19C9184BF1C48	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:JITWReptfMoij1Uy6y1e3Oa6dAs559292	rogid:Wl9L7AcvDHCZuKjYLn8QgGIbZTc9606	intact-crc:4DDE1898EFD3E361|rigid:UjXzjWJ+P5RZ9QrBKzqQGs1bp0w	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8N6L0	uniprotkb:P32453	intact:EBI-749265|uniprotkb:Q96MC3|ensembl:ENSP00000404220	intact:EBI-3306|uniprotkb:D6W0N0|ensemblfungi:YNL315C	psi-mi:kash5_human(display_long)|uniprotkb:KASH5(gene name)|psi-mi:KASH5(display_short)|uniprotkb:CCDC155(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 155(gene name synonym)|uniprotkb:KASH domain-containing protein 5(gene name synonym)	psi-mi:atp11_yeast(display_long)|uniprotkb:ATP11(gene name)|psi-mi:ATP11(display_short)|uniprotkb:N0357(orf name)|uniprotkb:YNL315C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552500|imex:IM-24995-3696	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_653289.3|ensembl:ENSG00000161609(gene)|ensembl:ENST00000447857(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034397"(telomere localization)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051225"(spindle assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0090172"(microtubule cytoskeleton organization involved in homologous chromosome segregation)|go:"GO:0090220"(chromosome localization to nuclear envelope involved in homologous chromosome segregation)|go:"GO:0090619"(meiotic spindle pole)|interpro:IPR011992(EF-Hand type)|interpro:IPR028168|interpro:IPR028170|interpro:IPR039508|mint:Q8N6L0|rcsb pdb:6R2I|rcsb pdb:6WMF	refseq:NP_014084.1|sgd:S000005259|dip:DIP-3026N|mint:P32453|ensemblfungi:YNL315C(gene)|ensemblfungi:YNL315C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0033615"(mitochondrial proton-transporting ATP synthase complex assembly)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR010591(ATP11)	-	-	crc64:61109AA4D338F2CD	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Wl9L7AcvDHCZuKjYLn8QgGIbZTc9606	rogid:JsQu6HtKtGqAVhHzaPVc8IMYdqM559292	intact-crc:3BE38CE08026E0CC|rigid:pDy+f65BuJZxYqNgX8MQxtuukRk	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P06197	uniprotkb:Q8N6L0	intact:EBI-13458|uniprotkb:D6W4B2|ensemblfungi:YPR113W	intact:EBI-749265|uniprotkb:Q96MC3|ensembl:ENSP00000404220	psi-mi:pis_yeast(display_long)|uniprotkb:PIS1(gene name)|psi-mi:PIS1(display_short)|uniprotkb:Phosphatidylinositol synthase(gene name synonym)|uniprotkb:PIS(gene name synonym)|uniprotkb:P8283.5(orf name)|uniprotkb:YPR113W(locus name)	psi-mi:kash5_human(display_long)|uniprotkb:KASH5(gene name)|psi-mi:KASH5(display_short)|uniprotkb:CCDC155(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 155(gene name synonym)|uniprotkb:KASH domain-containing protein 5(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552496|imex:IM-24995-3695	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015438.1|sgd:S000006317|mint:P06197|dip:DIP-3815N|ensemblfungi:YPR113W(gene)|ensemblfungi:YPR113W_mRNA(transcript)|go:"GO:0003881"(CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000462(CDP-alcohol phosphatidyltransferase)|interpro:IPR014387(CDP-diacylglycerol-inositol 3-phosphatidyltransferase, eukaryote)|interpro:IPR043130|reactome:R-SCE-1483226	refseq:NP_653289.3|ensembl:ENSG00000161609(gene)|ensembl:ENST00000447857(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034397"(telomere localization)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051225"(spindle assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0090172"(microtubule cytoskeleton organization involved in homologous chromosome segregation)|go:"GO:0090220"(chromosome localization to nuclear envelope involved in homologous chromosome segregation)|go:"GO:0090619"(meiotic spindle pole)|interpro:IPR011992(EF-Hand type)|interpro:IPR028168|interpro:IPR028170|interpro:IPR039508|mint:Q8N6L0|rcsb pdb:6R2I|rcsb pdb:6WMF	-	crc64:6E2E62252B3CB5E2	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:tdcTqpKpIDy8+8RRpLxehIeTrRU559292	rogid:Wl9L7AcvDHCZuKjYLn8QgGIbZTc9606	intact-crc:066307F4246A0312|rigid:9RrThZupbs1yPSEiQudQWJFGrpk	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P23968	uniprotkb:Q8N6L0	intact:EBI-20293|uniprotkb:D3DKX3|ensemblfungi:YHR026W	intact:EBI-749265|uniprotkb:Q96MC3|ensembl:ENSP00000404220	psi-mi:vato_yeast(display_long)|uniprotkb:VMA16(gene name)|psi-mi:VMA16(display_short)|uniprotkb:PPA1(gene name synonym)|uniprotkb:YHR026W(locus name)|uniprotkb:Vacuolar proton pump c'' subunit(gene name synonym)|uniprotkb:V-ATPase 22 kDa proteolipid subunit(gene name synonym)	psi-mi:kash5_human(display_long)|uniprotkb:KASH5(gene name)|psi-mi:KASH5(display_short)|uniprotkb:CCDC155(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 155(gene name synonym)|uniprotkb:KASH domain-containing protein 5(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552516|imex:IM-24995-3700	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011891.1|sgd:S000001068|rcsb pdb:6O7W|rcsb pdb:6O7X|rcsb pdb:6PE4|rcsb pdb:6PE5|reactome:R-SCE-1222556|reactome:R-SCE-77387|reactome:R-SCE-917977|reactome:R-SCE-9639288|ensemblfungi:YHR026W(gene)|ensemblfungi:YHR026W_mRNA(transcript)|go:"GO:0000220"(vacuolar proton-transporting V-type ATPase, V0 domain)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0008553"(P-type proton-exporting transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016471"(vacuolar proton-transporting V-type ATPase complex)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR000245(ATPase, V0 complex, proteolipid subunit C,)|interpro:IPR002379(ATPase, F0/V0 complex, subunit C)|interpro:IPR035921|rcsb pdb:5TJ5|rcsb pdb:5VOX|rcsb pdb:5VOY|rcsb pdb:5VOZ|rcsb pdb:6C6L|rcsb pdb:6M0R|rcsb pdb:6M0S|rcsb pdb:6O7T|rcsb pdb:6O7U|rcsb pdb:6O7V|dip:DIP-4054N|mint:P23968	refseq:NP_653289.3|ensembl:ENSG00000161609(gene)|ensembl:ENST00000447857(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034397"(telomere localization)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051225"(spindle assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0090172"(microtubule cytoskeleton organization involved in homologous chromosome segregation)|go:"GO:0090220"(chromosome localization to nuclear envelope involved in homologous chromosome segregation)|go:"GO:0090619"(meiotic spindle pole)|interpro:IPR011992(EF-Hand type)|interpro:IPR028168|interpro:IPR028170|interpro:IPR039508|mint:Q8N6L0|rcsb pdb:6R2I|rcsb pdb:6WMF	-	crc64:033FF5A516B97F8B	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:pQMMMGsUAtBoa6IF8yVU2t+odQQ559292	rogid:Wl9L7AcvDHCZuKjYLn8QgGIbZTc9606	intact-crc:575FC760DD7D0E4B|rigid:6kULBrDc7RKOSwU40SNKrsukouQ	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8N6L0	uniprotkb:Q12382	intact:EBI-749265|uniprotkb:Q96MC3|ensembl:ENSP00000404220	intact:EBI-36644|uniprotkb:D6W310|ensemblfungi:YOR311C	psi-mi:kash5_human(display_long)|uniprotkb:KASH5(gene name)|psi-mi:KASH5(display_short)|uniprotkb:CCDC155(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 155(gene name synonym)|uniprotkb:KASH domain-containing protein 5(gene name synonym)	psi-mi:dgk1_yeast(display_long)|uniprotkb:High-copy suppressor of SLY1 defect protein 1(gene name synonym)|uniprotkb:DGK1(gene name)|psi-mi:DGK1(display_short)|uniprotkb:HSD1(gene name synonym)|uniprotkb:O6111(orf name)|uniprotkb:YOR311C(locus name)|uniprotkb:Diglyceride kinase 1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552512|imex:IM-24995-3699	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_653289.3|ensembl:ENSG00000161609(gene)|ensembl:ENST00000447857(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034397"(telomere localization)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051225"(spindle assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0090172"(microtubule cytoskeleton organization involved in homologous chromosome segregation)|go:"GO:0090220"(chromosome localization to nuclear envelope involved in homologous chromosome segregation)|go:"GO:0090619"(meiotic spindle pole)|interpro:IPR011992(EF-Hand type)|interpro:IPR028168|interpro:IPR028170|interpro:IPR039508|mint:Q8N6L0|rcsb pdb:6R2I|rcsb pdb:6WMF	sgd:S000005838|refseq:NP_014956.3|dip:DIP-5021N|ensemblfungi:YOR311C(gene)|ensemblfungi:YOR311C_mRNA(transcript)|go:"GO:0004143"(diacylglycerol kinase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006654"(phosphatidic acid biosynthetic process)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:2001210"(regulation of isopentenyl diphosphate biosynthetic process, mevalonate pathway)|interpro:IPR037997	-	-	crc64:F8A0EE6F1018025B	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:Wl9L7AcvDHCZuKjYLn8QgGIbZTc9606	rogid:/QKdWOYiwS8WsUTob40AL05Q9Hw559292	intact-crc:C3157BD2AAB6DE8B|rigid:8uCgzyVNpSfPr0geC3hoJ0hbNeA	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P53012	uniprotkb:Q8N6L0	intact:EBI-16742|ensemblfungi:YGL126W|uniprotkb:E9P8W2|uniprotkb:D6VU22	intact:EBI-749265|uniprotkb:Q96MC3|ensembl:ENSP00000404220	psi-mi:scs3_yeast(display_long)|uniprotkb:SCS3(gene name)|psi-mi:SCS3(display_short)|uniprotkb:YGL126W(locus name)|uniprotkb:G2868(orf name)|uniprotkb:FIT2B(gene name synonym)|uniprotkb:FIT family protein SCS3(gene name synonym)	psi-mi:kash5_human(display_long)|uniprotkb:KASH5(gene name)|psi-mi:KASH5(display_short)|uniprotkb:CCDC155(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 155(gene name synonym)|uniprotkb:KASH domain-containing protein 5(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552508|imex:IM-24995-3698	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011389.3|ensemblfungi:YGL126W(gene)|ensemblfungi:YGL126W_mRNA(transcript)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006644"(phospholipid metabolic process)|go:"GO:0008654"(phospholipid biosynthetic process)|go:"GO:0016818"(hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides)|go:"GO:0019915"(lipid storage)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0034389"(lipid droplet organization)|go:"GO:0140042"(lipid droplet formation)|go:"GO:1900480"(regulation of diacylglycerol biosynthetic process)|go:"GO:1900481"(negative regulation of diacylglycerol biosynthetic process)|interpro:IPR019388|go:"GO:0005783"(endoplasmic reticulum)|sgd:S000003094|reactome:R-SCE-8964572|dip:DIP-1209N	refseq:NP_653289.3|ensembl:ENSG00000161609(gene)|ensembl:ENST00000447857(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034397"(telomere localization)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051225"(spindle assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0090172"(microtubule cytoskeleton organization involved in homologous chromosome segregation)|go:"GO:0090220"(chromosome localization to nuclear envelope involved in homologous chromosome segregation)|go:"GO:0090619"(meiotic spindle pole)|interpro:IPR011992(EF-Hand type)|interpro:IPR028168|interpro:IPR028170|interpro:IPR039508|mint:Q8N6L0|rcsb pdb:6R2I|rcsb pdb:6WMF	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:Hv4EhOlOeuhRkn8ZMn7vejwqoag559292	rogid:Wl9L7AcvDHCZuKjYLn8QgGIbZTc9606	intact-crc:7C11A3A93A8EEDBE|rigid:AiGxQzGNJCywWak4v2aAkBXyVv4	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P53142	uniprotkb:Q8N6L0	intact:EBI-23899|uniprotkb:D6VU42|ensemblfungi:YGL104C	intact:EBI-749265|uniprotkb:Q96MC3|ensembl:ENSP00000404220	psi-mi:vps73_yeast(display_long)|uniprotkb:VPS73(gene name)|psi-mi:VPS73(display_short)|uniprotkb:G3090(orf name)|uniprotkb:YGL104C(locus name)	psi-mi:kash5_human(display_long)|uniprotkb:KASH5(gene name)|psi-mi:KASH5(display_short)|uniprotkb:CCDC155(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 155(gene name synonym)|uniprotkb:KASH domain-containing protein 5(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552548|imex:IM-24995-3708	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003072|refseq:NP_011411.3|reactome:R-SCE-5653890|dip:DIP-1727N|reactome:R-SCE-189200|reactome:R-SCE-196836|reactome:R-SCE-422356|reactome:R-SCE-6798695|reactome:R-SCE-8981373|ensemblfungi:YGL104C(gene)|ensemblfungi:YGL104C_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005739"(mitochondrion)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0055085"(transmembrane transport)|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR020846|interpro:IPR036259	refseq:NP_653289.3|ensembl:ENSG00000161609(gene)|ensembl:ENST00000447857(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034397"(telomere localization)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051225"(spindle assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0090172"(microtubule cytoskeleton organization involved in homologous chromosome segregation)|go:"GO:0090220"(chromosome localization to nuclear envelope involved in homologous chromosome segregation)|go:"GO:0090619"(meiotic spindle pole)|interpro:IPR011992(EF-Hand type)|interpro:IPR028168|interpro:IPR028170|interpro:IPR039508|mint:Q8N6L0|rcsb pdb:6R2I|rcsb pdb:6WMF	-	crc64:D924D9112516450D	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:zkQIzKo7WxqNdwmETnOcsziImGk559292	rogid:Wl9L7AcvDHCZuKjYLn8QgGIbZTc9606	intact-crc:7B2D6D05A83FC30C|rigid:g0C5VCuajHxAAuy2R40a/94nheI	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8N6L0	uniprotkb:Q06616	intact:EBI-749265|uniprotkb:Q96MC3|ensembl:ENSP00000404220	intact:EBI-36065|uniprotkb:D6W4H5|ensemblfungi:YPR174C	psi-mi:kash5_human(display_long)|uniprotkb:KASH5(gene name)|psi-mi:KASH5(display_short)|uniprotkb:CCDC155(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 155(gene name synonym)|uniprotkb:KASH domain-containing protein 5(gene name synonym)	psi-mi:yp174_yeast(display_long)|uniprotkb:YPR174C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552544|imex:IM-24995-3707	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_653289.3|ensembl:ENSG00000161609(gene)|ensembl:ENST00000447857(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034397"(telomere localization)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051225"(spindle assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0090172"(microtubule cytoskeleton organization involved in homologous chromosome segregation)|go:"GO:0090220"(chromosome localization to nuclear envelope involved in homologous chromosome segregation)|go:"GO:0090619"(meiotic spindle pole)|interpro:IPR011992(EF-Hand type)|interpro:IPR028168|interpro:IPR028170|interpro:IPR039508|mint:Q8N6L0|rcsb pdb:6R2I|rcsb pdb:6WMF	refseq:NP_015500.1|sgd:S000006378|dip:DIP-3800N|ensemblfungi:YPR174C(gene)|ensemblfungi:YPR174C_mRNA(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034399"(nuclear periphery)|interpro:IPR013743(Nap binding NBP1, fungi)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:Wl9L7AcvDHCZuKjYLn8QgGIbZTc9606	rogid:R+7auDlEsOm+VR9gJ1jZsF3ST88559292	intact-crc:D291AED65E7BD365|rigid:HcU2H04ieLvzvIfH30kFyH3R7o0	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P53730	uniprotkb:Q8N6L0	intact:EBI-28496|uniprotkb:D6W1K4|ensemblfungi:YNR030W	intact:EBI-749265|uniprotkb:Q96MC3|ensembl:ENSP00000404220	psi-mi:alg12_yeast(display_long)|uniprotkb:ALG12(gene name)|psi-mi:ALG12(display_short)|uniprotkb:ECM39(gene name synonym)|uniprotkb:YNR030W(locus name)|uniprotkb:N3265(orf name)|uniprotkb:Mannosyltransferase ALG12(gene name synonym)|uniprotkb:Extracellular mutant protein 39(gene name synonym)|uniprotkb:"Dolichyl-P-Man:Man(7)GlcNAc(2)-PP-dolichyl-alpha-1,6-mannosyltransferase"(gene name synonym)|uniprotkb:Asparagine-linked glycosylation protein 12(gene name synonym)	psi-mi:kash5_human(display_long)|uniprotkb:KASH5(gene name)|psi-mi:KASH5(display_short)|uniprotkb:CCDC155(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 155(gene name synonym)|uniprotkb:KASH domain-containing protein 5(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552536|imex:IM-24995-3705	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014427.1|sgd:S000005313|dip:DIP-4259N|mint:P53730|ensemblfungi:YNR030W(gene)|ensemblfungi:YNR030W_mRNA(transcript)|go:"GO:0000009"(alpha-1,6-mannosyltransferase activity)|go:"GO:0000030"(mannosyltransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0006488"(dolichol-linked oligosaccharide biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0052917"("dolichyl-P-Man:Man(7)GlcNAc(2)-PP-dolichol alpha-1,6-mannosyltransferase")|interpro:IPR005599(Alg9-like mannosyltransferase)|interpro:IPR039485|reactome:R-SCE-446193	refseq:NP_653289.3|ensembl:ENSG00000161609(gene)|ensembl:ENST00000447857(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034397"(telomere localization)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051225"(spindle assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0090172"(microtubule cytoskeleton organization involved in homologous chromosome segregation)|go:"GO:0090220"(chromosome localization to nuclear envelope involved in homologous chromosome segregation)|go:"GO:0090619"(meiotic spindle pole)|interpro:IPR011992(EF-Hand type)|interpro:IPR028168|interpro:IPR028170|interpro:IPR039508|mint:Q8N6L0|rcsb pdb:6R2I|rcsb pdb:6WMF	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:3OdDOcUZm9NImnU+imd8xJwvb/Q559292	rogid:Wl9L7AcvDHCZuKjYLn8QgGIbZTc9606	intact-crc:95CEEA42B4BE06E7|rigid:zUZNmmlYHAgkp51A+owZX2vazzw	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P53906	uniprotkb:Q8N6L0	intact:EBI-28943|ensemblfungi:YNL146W|uniprotkb:D6W137	intact:EBI-749265|uniprotkb:Q96MC3|ensembl:ENSP00000404220	psi-mi:yno6_yeast(display_long)|uniprotkb:N1203(orf name)|uniprotkb:N1785(orf name)|uniprotkb:YNL146W(locus name)	psi-mi:kash5_human(display_long)|uniprotkb:KASH5(gene name)|psi-mi:KASH5(display_short)|uniprotkb:CCDC155(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 155(gene name synonym)|uniprotkb:KASH domain-containing protein 5(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552532|imex:IM-24995-3704	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005090|ensemblfungi:YNL146W(gene)|refseq:NP_014253.3|dip:DIP-8009N|ensemblfungi:YNL146W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)	refseq:NP_653289.3|ensembl:ENSG00000161609(gene)|ensembl:ENST00000447857(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034397"(telomere localization)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051225"(spindle assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0090172"(microtubule cytoskeleton organization involved in homologous chromosome segregation)|go:"GO:0090220"(chromosome localization to nuclear envelope involved in homologous chromosome segregation)|go:"GO:0090619"(meiotic spindle pole)|interpro:IPR011992(EF-Hand type)|interpro:IPR028168|interpro:IPR028170|interpro:IPR039508|mint:Q8N6L0|rcsb pdb:6R2I|rcsb pdb:6WMF	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:SvwjVFPBttBj4iLtjQSzRM4+w+E559292	rogid:Wl9L7AcvDHCZuKjYLn8QgGIbZTc9606	intact-crc:CA53A1ECF073B7EE|rigid:d3Li+yGLH97Yu1w/g+m3e/WKWPI	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q12259	uniprotkb:Q8N6L0	intact:EBI-30776|uniprotkb:D6VYA8|ensemblfungi:YLR108C	intact:EBI-749265|uniprotkb:Q96MC3|ensembl:ENSP00000404220	psi-mi:yl108_yeast(display_long)|uniprotkb:L2913(orf name)|uniprotkb:YLR108C(locus name)	psi-mi:kash5_human(display_long)|uniprotkb:KASH5(gene name)|psi-mi:KASH5(display_short)|uniprotkb:CCDC155(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 155(gene name synonym)|uniprotkb:KASH domain-containing protein 5(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552528|imex:IM-24995-3703	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013209.1|sgd:S000004098|dip:DIP-4075N|ensemblfungi:YLR108C(gene)|ensemblfungi:YLR108C_mRNA(transcript)|go:"GO:0005634"(nucleus)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)	refseq:NP_653289.3|ensembl:ENSG00000161609(gene)|ensembl:ENST00000447857(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034397"(telomere localization)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051225"(spindle assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0090172"(microtubule cytoskeleton organization involved in homologous chromosome segregation)|go:"GO:0090220"(chromosome localization to nuclear envelope involved in homologous chromosome segregation)|go:"GO:0090619"(meiotic spindle pole)|interpro:IPR011992(EF-Hand type)|interpro:IPR028168|interpro:IPR028170|interpro:IPR039508|mint:Q8N6L0|rcsb pdb:6R2I|rcsb pdb:6WMF	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:CzknxXhhvgMp3J0/oi197EgZ05U559292	rogid:Wl9L7AcvDHCZuKjYLn8QgGIbZTc9606	intact-crc:ADCB6ACF2FA9ADE3|rigid:CL3/fEzVgFnXthyaCwbA3LhmLeI	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8N6L0	uniprotkb:P38837	intact:EBI-749265|uniprotkb:Q96MC3|ensembl:ENSP00000404220	intact:EBI-24733|uniprotkb:D3DL82|uniprotkb:Q6Q5G1|ensemblfungi:YHR133C	psi-mi:kash5_human(display_long)|uniprotkb:KASH5(gene name)|psi-mi:KASH5(display_short)|uniprotkb:CCDC155(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 155(gene name synonym)|uniprotkb:KASH domain-containing protein 5(gene name synonym)	psi-mi:nsg1_yeast(display_long)|uniprotkb:INSIG homolog 1(gene name synonym)|uniprotkb:YHR133C(locus name)|uniprotkb:NSG1(gene name)|psi-mi:NSG1(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552524|imex:IM-24995-3702	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_653289.3|ensembl:ENSG00000161609(gene)|ensembl:ENST00000447857(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034397"(telomere localization)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051225"(spindle assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0090172"(microtubule cytoskeleton organization involved in homologous chromosome segregation)|go:"GO:0090220"(chromosome localization to nuclear envelope involved in homologous chromosome segregation)|go:"GO:0090619"(meiotic spindle pole)|interpro:IPR011992(EF-Hand type)|interpro:IPR028168|interpro:IPR028170|interpro:IPR039508|mint:Q8N6L0|rcsb pdb:6R2I|rcsb pdb:6WMF	sgd:S000001175|refseq:NP_012001.1|dip:DIP-2775N|mint:P38837|ensemblfungi:YHR133C(gene)|ensemblfungi:YHR133C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016126"(sterol biosynthetic process)|go:"GO:0034399"(nuclear periphery)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR025929	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Wl9L7AcvDHCZuKjYLn8QgGIbZTc9606	rogid:ALle5Ub0gjK3Uh+6sfIgbfa7BYw559292	intact-crc:F7CBBF369BC2AFC2|rigid:GGHvrnEzAxYlA3jNZxR9DvvfxHw	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q03579	uniprotkb:Q8N6L0	intact:EBI-27640|uniprotkb:D6W0C5|ensemblfungi:YMR298W	intact:EBI-749265|uniprotkb:Q96MC3|ensembl:ENSP00000404220	psi-mi:lip1_yeast(display_long)|uniprotkb:YMR298W(locus name)|uniprotkb:LIP1(gene name)|psi-mi:LIP1(display_short)|uniprotkb:LAG1/LAC1-interacting protein 1(gene name synonym)	psi-mi:kash5_human(display_long)|uniprotkb:KASH5(gene name)|psi-mi:KASH5(display_short)|uniprotkb:CCDC155(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 155(gene name synonym)|uniprotkb:KASH domain-containing protein 5(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552520|imex:IM-24995-3701	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014027.1|sgd:S000004913|dip:DIP-4392N|ensemblfungi:YMR298W(gene)|ensemblfungi:YMR298W_mRNA(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:0061576"(acyl-CoA ceramide synthase complex)	refseq:NP_653289.3|ensembl:ENSG00000161609(gene)|ensembl:ENST00000447857(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034397"(telomere localization)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051225"(spindle assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0090172"(microtubule cytoskeleton organization involved in homologous chromosome segregation)|go:"GO:0090220"(chromosome localization to nuclear envelope involved in homologous chromosome segregation)|go:"GO:0090619"(meiotic spindle pole)|interpro:IPR011992(EF-Hand type)|interpro:IPR028168|interpro:IPR028170|interpro:IPR039508|mint:Q8N6L0|rcsb pdb:6R2I|rcsb pdb:6WMF	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:9Z3aO01R1mik+xM40fm/dy+A/ec559292	rogid:Wl9L7AcvDHCZuKjYLn8QgGIbZTc9606	intact-crc:DB0FEB66E6969B35|rigid:4vBKopNrNkdVE82v9RXyHdI6Soc	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P53337	uniprotkb:Q8N6L0	intact:EBI-23662|uniprotkb:E9P8T4|uniprotkb:D6VV61|ensemblfungi:YGR284C	intact:EBI-749265|uniprotkb:Q96MC3|ensembl:ENSP00000404220	psi-mi:erv29_yeast(display_long)|uniprotkb:ERV29(gene name)|psi-mi:ERV29(display_short)|uniprotkb:YGR284C(locus name)	psi-mi:kash5_human(display_long)|uniprotkb:KASH5(gene name)|psi-mi:KASH5(display_short)|uniprotkb:CCDC155(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 155(gene name synonym)|uniprotkb:KASH domain-containing protein 5(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552540|imex:IM-24995-3706	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011800.3|sgd:S000003516|dip:DIP-8110N|mint:P53337|ensemblfungi:YGR284C(gene)|ensemblfungi:YGR284C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0097020"(COPII receptor activity)|interpro:IPR002995(Surfeit locus 4)|reactome:R-SCE-6798695|reactome:R-SCE-6811434	refseq:NP_653289.3|ensembl:ENSG00000161609(gene)|ensembl:ENST00000447857(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034397"(telomere localization)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051225"(spindle assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0090172"(microtubule cytoskeleton organization involved in homologous chromosome segregation)|go:"GO:0090220"(chromosome localization to nuclear envelope involved in homologous chromosome segregation)|go:"GO:0090619"(meiotic spindle pole)|interpro:IPR011992(EF-Hand type)|interpro:IPR028168|interpro:IPR028170|interpro:IPR039508|mint:Q8N6L0|rcsb pdb:6R2I|rcsb pdb:6WMF	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:vlRDf0B9mDUXU6M2tLAiWqX4wN8559292	rogid:Wl9L7AcvDHCZuKjYLn8QgGIbZTc9606	intact-crc:73BCD65BBFD88FCE|rigid:tBRhPS3XijxnDuDFWhH4kh8Nlf0	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P40014	uniprotkb:Q8N6Y0	intact:EBI-22458|uniprotkb:D3DLR6|ensemblfungi:YER018C	intact:EBI-739895|uniprotkb:Q8NBX7|uniprotkb:Q96KH3|uniprotkb:Q9BYI8|uniprotkb:A8K7L6|uniprotkb:B2RCR9|ensembl:ENSP00000252597	psi-mi:spc25_yeast(display_long)|uniprotkb:YER018C(locus name)|uniprotkb:SPC25(gene name)|psi-mi:SPC25(display_short)	psi-mi:usbp1_human(display_long)|uniprotkb:USHBP1(gene name)|psi-mi:USHBP1(display_short)|uniprotkb:MCC-2(gene name synonym)|uniprotkb:AIE-75-binding protein(gene name synonym)|uniprotkb:AIEBP(gene name synonym)|uniprotkb:MCC2(gene name synonym)|uniprotkb:Mutated in colon cancer protein 2(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552556|imex:IM-24995-3710	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010934.3|sgd:S000000820|dip:DIP-2990N|mint:P40014|ensemblfungi:YER018C(gene)|ensemblfungi:YER018C_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0051301"(cell division)|go:"GO:0098653"(centromere clustering)|interpro:IPR038066|rcsb pdb:2FTX|rcsb pdb:2FV4|rcsb pdb:4GEQ|rcsb pdb:5T6J|rcsb pdb:5TCS|rcsb pdb:5TD8|rcsb pdb:7KDF	refseq:NP_001284632.1|refseq:NP_114147.2|refseq:NP_001308346.1|ensembl:ENSG00000130307(gene)|ensembl:ENST00000252597(transcript)|go:"GO:0030165"(PDZ domain binding)|interpro:IPR019536|interpro:IPR040171	-	crc64:1BED6CCFF330A5D8	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:i5gKRZA7GAjnCVzuX/qP8YmpQRA559292	rogid:vY1qx73Ju/z7WDu6k1kd10ZDVRo9606	intact-crc:14FE09FBE133022C|rigid:rDgEicRDXpzi4eKB+1VHat4fpJ0	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P35180	uniprotkb:Q8N6Y0	intact:EBI-12522|uniprotkb:D6VUL4|ensemblfungi:YGR082W	intact:EBI-739895|uniprotkb:Q8NBX7|uniprotkb:Q96KH3|uniprotkb:Q9BYI8|uniprotkb:A8K7L6|uniprotkb:B2RCR9|ensembl:ENSP00000252597	psi-mi:tom20_yeast(display_long)|uniprotkb:MOM19(gene name synonym)|uniprotkb:YGR082W(locus name)|uniprotkb:TOM20(gene name)|psi-mi:TOM20(display_short)|uniprotkb:MAS20(gene name synonym)|uniprotkb:Mitochondrial 20 kDa outer membrane protein(gene name synonym)|uniprotkb:Translocase of outer membrane 20 kDa subunit(gene name synonym)|uniprotkb:Protein MAS20(gene name synonym)	psi-mi:usbp1_human(display_long)|uniprotkb:USHBP1(gene name)|psi-mi:USHBP1(display_short)|uniprotkb:MCC-2(gene name synonym)|uniprotkb:AIE-75-binding protein(gene name synonym)|uniprotkb:AIEBP(gene name synonym)|uniprotkb:MCC2(gene name synonym)|uniprotkb:Mutated in colon cancer protein 2(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552560|imex:IM-24995-3711	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YGR082W(gene)|ensemblfungi:YGR082W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005742"(mitochondrial outer membrane translocase complex)|go:"GO:0016031"(tRNA import into mitochondrion)|go:"GO:0030150"(protein import into mitochondrial matrix)|go:"GO:0030943"(mitochondrion targeting sequence binding)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|interpro:IPR002056(Protein import receptor MAS20)|interpro:IPR023392|refseq:NP_011596.1|sgd:S000003314|dip:DIP-2539N|mint:P35180	refseq:NP_001284632.1|refseq:NP_114147.2|refseq:NP_001308346.1|ensembl:ENSG00000130307(gene)|ensembl:ENST00000252597(transcript)|go:"GO:0030165"(PDZ domain binding)|interpro:IPR019536|interpro:IPR040171	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:7U00YLVWcaegWlJEKzGblv6STx4559292	rogid:vY1qx73Ju/z7WDu6k1kd10ZDVRo9606	intact-crc:61166078F0EC2ABB|rigid:vYGsXdseBt/8LAaKlng/wBgT/jY	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P43592	uniprotkb:Q8N6Y0	intact:EBI-22932|uniprotkb:D6VTN8|ensemblfungi:YFR008W	intact:EBI-739895|uniprotkb:Q8NBX7|uniprotkb:Q96KH3|uniprotkb:Q9BYI8|uniprotkb:A8K7L6|uniprotkb:B2RCR9|ensembl:ENSP00000252597	psi-mi:far7_yeast(display_long)|uniprotkb:YFR008W(locus name)|uniprotkb:FAR7(gene name)|psi-mi:FAR7(display_short)	psi-mi:usbp1_human(display_long)|uniprotkb:USHBP1(gene name)|psi-mi:USHBP1(display_short)|uniprotkb:MCC-2(gene name synonym)|uniprotkb:AIE-75-binding protein(gene name synonym)|uniprotkb:AIEBP(gene name synonym)|uniprotkb:MCC2(gene name synonym)|uniprotkb:Mutated in colon cancer protein 2(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552564|imex:IM-24995-3712	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000001904|refseq:NP_116663.1|dip:DIP-1315N|mint:P43592|ensemblfungi:YFR008W(gene)|ensemblfungi:YFR008W_mRNA(transcript)|go:"GO:0000321"(re-entry into mitotic cell cycle after pheromone arrest)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)	refseq:NP_001284632.1|refseq:NP_114147.2|refseq:NP_001308346.1|ensembl:ENSG00000130307(gene)|ensembl:ENST00000252597(transcript)|go:"GO:0030165"(PDZ domain binding)|interpro:IPR019536|interpro:IPR040171	-	crc64:81156978FF7AAD54	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:RB7IaPAzOtEtryalHHz8psxOYqw559292	rogid:vY1qx73Ju/z7WDu6k1kd10ZDVRo9606	intact-crc:BD89BAF1053D05C9|rigid:SHiwDECj2vArFtny+DqMP2mvmOI	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8N6Y0	uniprotkb:P28004	intact:EBI-739895|uniprotkb:Q8NBX7|uniprotkb:Q96KH3|uniprotkb:Q9BYI8|uniprotkb:A8K7L6|uniprotkb:B2RCR9|ensembl:ENSP00000252597	intact:EBI-20640|uniprotkb:D6VPI6|ensemblfungi:YAL032C	psi-mi:usbp1_human(display_long)|uniprotkb:USHBP1(gene name)|psi-mi:USHBP1(display_short)|uniprotkb:MCC-2(gene name synonym)|uniprotkb:AIE-75-binding protein(gene name synonym)|uniprotkb:AIEBP(gene name synonym)|uniprotkb:MCC2(gene name synonym)|uniprotkb:Mutated in colon cancer protein 2(gene name synonym)	psi-mi:prp45_yeast(display_long)|uniprotkb:YAL032C(locus name)|uniprotkb:PRP45(gene name)|psi-mi:PRP45(display_short)|uniprotkb:FUN20(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552568|imex:IM-24995-3713	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001284632.1|refseq:NP_114147.2|refseq:NP_001308346.1|ensembl:ENSG00000130307(gene)|ensembl:ENST00000252597(transcript)|go:"GO:0030165"(PDZ domain binding)|interpro:IPR019536|interpro:IPR040171	refseq:NP_009370.1|sgd:S000000030|ensemblfungi:YAL032C(gene)|ensemblfungi:YAL032C_mRNA(transcript)|go:"GO:0000350"(generation of catalytic spliceosome for second transesterification step)|go:"GO:0005634"(nucleus)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|interpro:IPR004015(SKIP/SNW)|interpro:IPR017862|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|dip:DIP-2774N|mint:P28004	-	-	crc64:FE5A724186D7FE84	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:vY1qx73Ju/z7WDu6k1kd10ZDVRo9606	rogid:qoHF1UsO3k+JOTOfigSuy2P84/k559292	intact-crc:7F75D4D52AB4AEFE|rigid:58s9BfEOehK3LAa3Idmi3Xjo3vE	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P26448	uniprotkb:Q8N6Y0	intact:EBI-3824|uniprotkb:D6VZN0|ensemblfungi:YMR055C	intact:EBI-739895|uniprotkb:Q8NBX7|uniprotkb:Q96KH3|uniprotkb:Q9BYI8|uniprotkb:A8K7L6|uniprotkb:B2RCR9|ensembl:ENSP00000252597	psi-mi:bub2_yeast(display_long)|uniprotkb:BUB2(gene name)|psi-mi:BUB2(display_short)|uniprotkb:YMR055C(locus name)|uniprotkb:YM9796.08C(orf name)|uniprotkb:Cell cycle arrest protein BUB2(gene name synonym)	psi-mi:usbp1_human(display_long)|uniprotkb:USHBP1(gene name)|psi-mi:USHBP1(display_short)|uniprotkb:MCC-2(gene name synonym)|uniprotkb:AIE-75-binding protein(gene name synonym)|uniprotkb:AIEBP(gene name synonym)|uniprotkb:MCC2(gene name synonym)|uniprotkb:Mutated in colon cancer protein 2(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552572|imex:IM-24995-3714	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013771.1|sgd:S000004659|dip:DIP-1215N|mint:P26448|ensemblfungi:YMR055C(gene)|ensemblfungi:YMR055C_mRNA(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0031030"(negative regulation of septation initiation signaling)|go:"GO:0031578"(mitotic spindle orientation checkpoint signaling)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0051301"(cell division)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:1902543"(negative regulation of protein localization to mitotic spindle pole body)|go:"GO:1990334"(Bfa1-Bub2 complex)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR035969	refseq:NP_001284632.1|refseq:NP_114147.2|refseq:NP_001308346.1|ensembl:ENSG00000130307(gene)|ensembl:ENST00000252597(transcript)|go:"GO:0030165"(PDZ domain binding)|interpro:IPR019536|interpro:IPR040171	-	crc64:A1DDBFB548E81EA3	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:+03m4HOOcKjpSjqpEZ8wCgD2Egc559292	rogid:vY1qx73Ju/z7WDu6k1kd10ZDVRo9606	intact-crc:9EBCD17F22E7E33E|rigid:OJuPXnRBhcxEYj7Fg2EWN3c+DGI	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P48232	uniprotkb:Q8N6Y0	intact:EBI-28775|uniprotkb:D6W193|ensemblfungi:YNL086W	intact:EBI-739895|uniprotkb:Q8NBX7|uniprotkb:Q96KH3|uniprotkb:Q9BYI8|uniprotkb:A8K7L6|uniprotkb:B2RCR9|ensembl:ENSP00000252597	psi-mi:snapn_yeast(display_long)|uniprotkb:YNL086W(locus name)|uniprotkb:N2254(orf name)|uniprotkb:SNN1(gene name)|psi-mi:SNN1(display_short)|uniprotkb:SNAPIN-like protein 1(gene name synonym)	psi-mi:usbp1_human(display_long)|uniprotkb:USHBP1(gene name)|psi-mi:USHBP1(display_short)|uniprotkb:MCC-2(gene name synonym)|uniprotkb:AIE-75-binding protein(gene name synonym)|uniprotkb:AIEBP(gene name synonym)|uniprotkb:MCC2(gene name synonym)|uniprotkb:Mutated in colon cancer protein 2(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552576|imex:IM-24995-3715	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014313.1|sgd:S000005030|dip:DIP-1188N|mint:P48232|ensemblfungi:YNL086W(gene)|ensemblfungi:YNL086W_mRNA(transcript)|go:"GO:0005768"(endosome)|go:"GO:0007032"(endosome organization)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0032880"(regulation of protein localization)	refseq:NP_001284632.1|refseq:NP_114147.2|refseq:NP_001308346.1|ensembl:ENSG00000130307(gene)|ensembl:ENST00000252597(transcript)|go:"GO:0030165"(PDZ domain binding)|interpro:IPR019536|interpro:IPR040171	-	crc64:33200D2F0F729DA1	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:XCPaHuGC9oKD/3W0gY5ZY8jKtFs559292	rogid:vY1qx73Ju/z7WDu6k1kd10ZDVRo9606	intact-crc:200054E9C433D626|rigid:DY0xKzsTS1LyJKp5ymhNiy00JT8	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8N6L0	uniprotkb:P11972	intact:EBI-749265|uniprotkb:Q96MC3|ensembl:ENSP00000404220	intact:EBI-18232|uniprotkb:Q06207|uniprotkb:D6VZ86|ensemblfungi:YLR452C	psi-mi:kash5_human(display_long)|uniprotkb:KASH5(gene name)|psi-mi:KASH5(display_short)|uniprotkb:CCDC155(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 155(gene name synonym)|uniprotkb:KASH domain-containing protein 5(gene name synonym)	psi-mi:sst2_yeast(display_long)|uniprotkb:SST2(gene name)|psi-mi:SST2(display_short)|uniprotkb:L9324.9(orf name)|uniprotkb:YLR452C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552552|imex:IM-24995-3709	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_653289.3|ensembl:ENSG00000161609(gene)|ensembl:ENST00000447857(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034397"(telomere localization)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051225"(spindle assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0090172"(microtubule cytoskeleton organization involved in homologous chromosome segregation)|go:"GO:0090220"(chromosome localization to nuclear envelope involved in homologous chromosome segregation)|go:"GO:0090619"(meiotic spindle pole)|interpro:IPR011992(EF-Hand type)|interpro:IPR028168|interpro:IPR028170|interpro:IPR039508|mint:Q8N6L0|rcsb pdb:6R2I|rcsb pdb:6WMF	refseq:NP_013557.1|sgd:S000004444|ensemblfungi:YLR452C(gene)|ensemblfungi:YLR452C_mRNA(transcript)|go:"GO:0000754"(adaptation of signaling pathway by response to pheromone involved in conjugation with cellular fusion)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0009968"(negative regulation of signal transduction)|go:"GO:0035556"(intracellular signal transduction)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR036305|interpro:IPR036388|interpro:IPR036390|interpro:IPR016137(Regulator of G protein signalling superfamily)|dip:DIP-2354N|mint:P11972	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:Wl9L7AcvDHCZuKjYLn8QgGIbZTc9606	rogid:a452jzptv3MtejNfc+LDrwSFSks559292	intact-crc:3D9CEAEB2BD36315|rigid:rEa7jcAmNBUUvSpnXWFPLwT8+Fg	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q02831	uniprotkb:Q8N6Y0	intact:EBI-31828|uniprotkb:D6W3T9|ensemblfungi:YPL077C	intact:EBI-739895|uniprotkb:Q8NBX7|uniprotkb:Q96KH3|uniprotkb:Q9BYI8|uniprotkb:A8K7L6|uniprotkb:B2RCR9|ensembl:ENSP00000252597	psi-mi:yp077_yeast(display_long)|uniprotkb:YPL077C(locus name)	psi-mi:usbp1_human(display_long)|uniprotkb:USHBP1(gene name)|psi-mi:USHBP1(display_short)|uniprotkb:MCC-2(gene name synonym)|uniprotkb:AIE-75-binding protein(gene name synonym)|uniprotkb:AIEBP(gene name synonym)|uniprotkb:MCC2(gene name synonym)|uniprotkb:Mutated in colon cancer protein 2(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552604|imex:IM-24995-3722	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005998|refseq:NP_015248.1|dip:DIP-4022N|ensemblfungi:YPL077C(gene)|ensemblfungi:YPL077C_mRNA(transcript)	refseq:NP_001284632.1|refseq:NP_114147.2|refseq:NP_001308346.1|ensembl:ENSG00000130307(gene)|ensembl:ENST00000252597(transcript)|go:"GO:0030165"(PDZ domain binding)|interpro:IPR019536|interpro:IPR040171	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:yqOn4GWKNmFZ7UvGmyBEpgoyKlA559292	rogid:vY1qx73Ju/z7WDu6k1kd10ZDVRo9606	intact-crc:4586E04487F13C83|rigid:A6DAO/TQOlWtb+Y+m+iQwuLfKpM	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P47133	uniprotkb:Q8N6Y0	intact:EBI-25568|uniprotkb:D6VWQ6|uniprotkb:Q66R61|ensemblfungi:YJR088C	intact:EBI-739895|uniprotkb:Q8NBX7|uniprotkb:Q96KH3|uniprotkb:Q9BYI8|uniprotkb:A8K7L6|uniprotkb:B2RCR9|ensembl:ENSP00000252597	psi-mi:emc2_yeast(display_long)|uniprotkb:EMC2(gene name)|psi-mi:EMC2(display_short)|uniprotkb:J1875(orf name)|uniprotkb:YJR088C(locus name)	psi-mi:usbp1_human(display_long)|uniprotkb:USHBP1(gene name)|psi-mi:USHBP1(display_short)|uniprotkb:MCC-2(gene name synonym)|uniprotkb:AIE-75-binding protein(gene name synonym)|uniprotkb:AIEBP(gene name synonym)|uniprotkb:MCC2(gene name synonym)|uniprotkb:Mutated in colon cancer protein 2(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552600|imex:IM-24995-3721	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012621.1|sgd:S000003848|dip:DIP-7609N|ensemblfungi:YJR088C(gene)|ensemblfungi:YJR088C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0072546"(EMC complex)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR039856|rcsb pdb:6WB9|rcsb pdb:7KRA|rcsb pdb:7KTX	refseq:NP_001284632.1|refseq:NP_114147.2|refseq:NP_001308346.1|ensembl:ENSG00000130307(gene)|ensembl:ENST00000252597(transcript)|go:"GO:0030165"(PDZ domain binding)|interpro:IPR019536|interpro:IPR040171	-	crc64:157A03E75FB9E72A	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:p1r7k3QtfCRO93w9iBzh6wYGL9Q559292	rogid:vY1qx73Ju/z7WDu6k1kd10ZDVRo9606	intact-crc:48A23DEED482A0F0|rigid:FYmRLOyXsbEWBakVmoQuJEvha18	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8N6Y0	uniprotkb:P20053	intact:EBI-739895|uniprotkb:Q8NBX7|uniprotkb:Q96KH3|uniprotkb:Q9BYI8|uniprotkb:A8K7L6|uniprotkb:B2RCR9|ensembl:ENSP00000252597	intact:EBI-219|uniprotkb:D6W4H8|ensemblfungi:YPR178W	psi-mi:usbp1_human(display_long)|uniprotkb:USHBP1(gene name)|psi-mi:USHBP1(display_short)|uniprotkb:MCC-2(gene name synonym)|uniprotkb:AIE-75-binding protein(gene name synonym)|uniprotkb:AIEBP(gene name synonym)|uniprotkb:MCC2(gene name synonym)|uniprotkb:Mutated in colon cancer protein 2(gene name synonym)	psi-mi:prp4_yeast(display_long)|uniprotkb:PRP4(gene name)|psi-mi:PRP4(display_short)|uniprotkb:RNA4(gene name synonym)|uniprotkb:YPR178W(locus name)|uniprotkb:P9705.6(orf name)|uniprotkb:Pre-mRNA-processing protein 4(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552596|imex:IM-24995-3720	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001284632.1|refseq:NP_114147.2|refseq:NP_001308346.1|ensembl:ENSG00000130307(gene)|ensembl:ENST00000252597(transcript)|go:"GO:0030165"(PDZ domain binding)|interpro:IPR019536|interpro:IPR040171	refseq:NP_015504.1|sgd:S000006382|mint:P20053|dip:DIP-2607N|ensemblfungi:YPR178W(gene)|ensemblfungi:YPR178W_mRNA(transcript)|go:"GO:0000393"(spliceosomal conformational changes to generate catalytic conformation)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0030621"(U4 snRNA binding)|go:"GO:0034247"(snoRNA splicing)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR014906("Pre-mRNA processing factor 4 (PRP4) like")|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|rcsb pdb:3JCM|rcsb pdb:5GAN|rcsb pdb:5GAP|rcsb pdb:5NRL|rcsb pdb:5ZWM|rcsb pdb:5ZWO	-	-	crc64:7CCCA3A92AC0CE78	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:vY1qx73Ju/z7WDu6k1kd10ZDVRo9606	rogid:vvz5G0rqqyrugTvAPelDKit9FpQ559292	intact-crc:6D323B765A3403A5|rigid:oGHx2Y1m3J2Qzbyujb+NjaM4buI	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8N6Y0	uniprotkb:P32571	intact:EBI-739895|uniprotkb:Q8NBX7|uniprotkb:Q96KH3|uniprotkb:Q9BYI8|uniprotkb:A8K7L6|uniprotkb:B2RCR9|ensembl:ENSP00000252597	intact:EBI-19840|uniprotkb:D6VS55|ensemblfungi:YDR069C	psi-mi:usbp1_human(display_long)|uniprotkb:USHBP1(gene name)|psi-mi:USHBP1(display_short)|uniprotkb:MCC-2(gene name synonym)|uniprotkb:AIE-75-binding protein(gene name synonym)|uniprotkb:AIEBP(gene name synonym)|uniprotkb:MCC2(gene name synonym)|uniprotkb:Mutated in colon cancer protein 2(gene name synonym)	psi-mi:ubp4_yeast(display_long)|uniprotkb:DOA4(gene name)|psi-mi:DOA4(display_short)|uniprotkb:MUT4(gene name synonym)|uniprotkb:SSV7(gene name synonym)|uniprotkb:YDR069C(locus name)|uniprotkb:YD9609.23C(orf name)|uniprotkb:YD8554.02C(orf name)|uniprotkb:D4270(orf name)|uniprotkb:NPI2(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 4(gene name synonym)|uniprotkb:Deubiquitinating enzyme 4(gene name synonym)|uniprotkb:Vacuole biogenesis protein SSV7(gene name synonym)|uniprotkb:Ubiquitin thioesterase 4(gene name synonym)|uniprotkb:DOS1(gene name synonym)|uniprotkb:UBP4(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552580|imex:IM-24995-3716	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001284632.1|refseq:NP_114147.2|refseq:NP_001308346.1|ensembl:ENSG00000130307(gene)|ensembl:ENST00000252597(transcript)|go:"GO:0030165"(PDZ domain binding)|interpro:IPR019536|interpro:IPR040171	sgd:S000002476|ensemblfungi:YDR069C(gene)|ensemblfungi:YDR069C_mRNA(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005739"(mitochondrion)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0010992"(ubiquitin recycling)|go:"GO:0010995"(free ubiquitin chain depolymerization)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0031902"(late endosome membrane)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0070676"(intralumenal vesicle formation)|go:"GO:1904669"(ATP export)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR001763(Rhodanese-like)|interpro:IPR018200|interpro:IPR028889|interpro:IPR036873|interpro:IPR038765|refseq:NP_010354.3|dip:DIP-5298N|mint:P32571	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:vY1qx73Ju/z7WDu6k1kd10ZDVRo9606	rogid:UTBSWmpygyxo1ygxp/sQ8wgqnMo559292	intact-crc:D0F11E924246F6F5|rigid:DN8zgK0GuI+aCXH3yiBoVoqrj3U	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q06162	uniprotkb:Q8N6Y0	intact:EBI-34256|uniprotkb:D6VYV9|ensemblfungi:YLR315W	intact:EBI-739895|uniprotkb:Q8NBX7|uniprotkb:Q96KH3|uniprotkb:Q9BYI8|uniprotkb:A8K7L6|uniprotkb:B2RCR9|ensembl:ENSP00000252597	psi-mi:nkp2_yeast(display_long)|uniprotkb:NKP2(gene name)|psi-mi:NKP2(display_short)|uniprotkb:Non-essential kinetochore protein 2(gene name synonym)|uniprotkb:YLR315W(locus name)|uniprotkb:Constitutive centromere-associated network protein NKP2(gene name synonym)	psi-mi:usbp1_human(display_long)|uniprotkb:USHBP1(gene name)|psi-mi:USHBP1(display_short)|uniprotkb:MCC-2(gene name synonym)|uniprotkb:AIE-75-binding protein(gene name synonym)|uniprotkb:AIEBP(gene name synonym)|uniprotkb:MCC2(gene name synonym)|uniprotkb:Mutated in colon cancer protein 2(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552588|imex:IM-24995-3718	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000004307|refseq:NP_013419.1|mint:Q06162|dip:DIP-1939N|ensemblfungi:YLR315W(gene)|ensemblfungi:YLR315W_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0007059"(chromosome segregation)|go:"GO:0031511"(Mis6-Sim4 complex)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|interpro:IPR018565|rcsb pdb:6NUW|rcsb pdb:6QLD|rcsb pdb:6QLE|rcsb pdb:6QLF	refseq:NP_001284632.1|refseq:NP_114147.2|refseq:NP_001308346.1|ensembl:ENSG00000130307(gene)|ensembl:ENST00000252597(transcript)|go:"GO:0030165"(PDZ domain binding)|interpro:IPR019536|interpro:IPR040171	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:MT2+IEz8xQ2SVU5vvYYBI91cVKo559292	rogid:vY1qx73Ju/z7WDu6k1kd10ZDVRo9606	intact-crc:47EEF0752AC03BD8|rigid:Rq472ti3Fh+ZBVW5tCcxmNtu0/I	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
intact:EBI-11522208	uniprotkb:Q8N6Y0	-	intact:EBI-739895|uniprotkb:Q8NBX7|uniprotkb:Q96KH3|uniprotkb:Q9BYI8|uniprotkb:A8K7L6|uniprotkb:B2RCR9|ensembl:ENSP00000252597	psi-mi:ylr445w(display_short)|psi-mi:EBI-11522208(display_long)	psi-mi:usbp1_human(display_long)|uniprotkb:USHBP1(gene name)|psi-mi:USHBP1(display_short)|uniprotkb:MCC-2(gene name synonym)|uniprotkb:AIE-75-binding protein(gene name synonym)|uniprotkb:AIEBP(gene name synonym)|uniprotkb:MCC2(gene name synonym)|uniprotkb:Mutated in colon cancer protein 2(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552584|imex:IM-24995-3717	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001284632.1|refseq:NP_114147.2|refseq:NP_001308346.1|ensembl:ENSG00000130307(gene)|ensembl:ENST00000252597(transcript)|go:"GO:0030165"(PDZ domain binding)|interpro:IPR019536|interpro:IPR040171	-	no-uniprot-update:	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:kUe7etYjGLH6i6KZ5N2LXUnjAf04932	rogid:vY1qx73Ju/z7WDu6k1kd10ZDVRo9606	intact-crc:4BF40784F7C9C37D|rigid:ZdV5IG7C1GfGBnajMMlqxT7pdQc	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8N6Y0	uniprotkb:P48837	intact:EBI-739895|uniprotkb:Q8NBX7|uniprotkb:Q96KH3|uniprotkb:Q9BYI8|uniprotkb:A8K7L6|uniprotkb:B2RCR9|ensembl:ENSP00000252597	intact:EBI-12324|ensemblfungi:YGR119C|uniprotkb:D6VUQ0	psi-mi:usbp1_human(display_long)|uniprotkb:USHBP1(gene name)|psi-mi:USHBP1(display_short)|uniprotkb:MCC-2(gene name synonym)|uniprotkb:AIE-75-binding protein(gene name synonym)|uniprotkb:AIEBP(gene name synonym)|uniprotkb:MCC2(gene name synonym)|uniprotkb:Mutated in colon cancer protein 2(gene name synonym)	psi-mi:nup57_yeast(display_long)|uniprotkb:NUP57(gene name)|psi-mi:NUP57(display_short)|uniprotkb:YGR119C(locus name)|uniprotkb:G6320(orf name)|uniprotkb:Nuclear pore protein NUP57(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552592|imex:IM-24995-3719	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001284632.1|refseq:NP_114147.2|refseq:NP_001308346.1|ensembl:ENSG00000130307(gene)|ensembl:ENST00000252597(transcript)|go:"GO:0030165"(PDZ domain binding)|interpro:IPR019536|interpro:IPR040171	ensemblfungi:YGR119C(gene)|ensemblfungi:YGR119C_mRNA(transcript)|go:"GO:0005643"(nuclear pore)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036228"(protein localization to nuclear inner membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0051028"(mRNA transport)|interpro:IPR024864|interpro:IPR025574|interpro:IPR025712|refseq:NP_011634.1|sgd:S000003351|mint:P48837|dip:DIP-866N	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:vY1qx73Ju/z7WDu6k1kd10ZDVRo9606	rogid:ultDTflWHx7n/y2FrlWFf+lBKmw559292	intact-crc:CBAB90272A8A1F1C|rigid:JZ0fyuEAWv0wjPEHyZnsVFCGo1M	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8N7W2-2	uniprotkb:Q12161	intact:EBI-10181188|ensembl:ENSP00000367868	intact:EBI-34372|uniprotkb:D6W213|ensemblfungi:YOL054W	psi-mi:q8n7w2-2(display_long)|uniprotkb:C10orf30(gene name synonym)|uniprotkb:BEND7(gene name)|psi-mi:BEND7(display_short)	psi-mi:psh1_yeast(display_long)|uniprotkb:PSH1(gene name)|psi-mi:PSH1(display_short)|uniprotkb:POB3/SPT16 histone-associated protein 1(gene name synonym)|uniprotkb:O1263(orf name)|uniprotkb:YOL054W(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552628|imex:IM-24995-3728	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000165626(gene)|ensembl:ENST00000378605(transcript)|intact:EBI-743382(isoform-parent)|uniprotkb:Q8N7W2-2(isoform-parent)	refseq:NP_014587.1|sgd:S000005415|mint:Q12161|dip:DIP-6481N|ensemblfungi:YOL054W(gene)|ensemblfungi:YOL054W_mRNA(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907	-	-	crc64:CE0ECBCB6D465554	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:p6qrTn80hLyVU0W2Tvwn50Q4m5I9606	rogid:AvPMRd/GjfaTyQjEfMPhBVcvOs4559292	intact-crc:1B9ACF088D236530|rigid:KM2IIjxphzbMyRqwAMNC5CTyd7g	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8N7W2-2	uniprotkb:P35184	intact:EBI-10181188|ensembl:ENSP00000367868	intact:EBI-17971|uniprotkb:D6VVU2|ensemblfungi:YIR012W	psi-mi:q8n7w2-2(display_long)|uniprotkb:C10orf30(gene name synonym)|uniprotkb:BEND7(gene name)|psi-mi:BEND7(display_short)	psi-mi:sqt1_yeast(display_long)|uniprotkb:YIB12W(orf name)|uniprotkb:YIR012W(locus name)|uniprotkb:SQT1(gene name)|psi-mi:SQT1(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552624|imex:IM-24995-3727	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000165626(gene)|ensembl:ENST00000378605(transcript)|intact:EBI-743382(isoform-parent)|uniprotkb:Q8N7W2-2(isoform-parent)	refseq:NP_012277.1|sgd:S000001451|ensemblfungi:YIR012W_mRNA(transcript)|ensemblfungi:YIR012W(gene)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|rcsb pdb:4ZOV|rcsb pdb:4ZOX|rcsb pdb:5AMS|dip:DIP-2508N|mint:P35184	-	-	crc64:981D566076B0C881	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:p6qrTn80hLyVU0W2Tvwn50Q4m5I9606	rogid:u/Q5uAjR85ZD3op0nHiN20IVCLY559292	intact-crc:F6212E267EEDB3AE|rigid:toOVjX2vGMz6qqn4DYa1Ab6pYvg	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P40454	uniprotkb:Q8N7W2-2	intact:EBI-25278|uniprotkb:D6VVD4|ensemblfungi:YIL153W	intact:EBI-10181188|ensembl:ENSP00000367868	psi-mi:ptpa1_yeast(display_long)|uniprotkb:YIL153W(locus name)|uniprotkb:RRD1(gene name)|psi-mi:RRD1(display_short)|uniprotkb:NCS1(gene name synonym)|uniprotkb:YPA1(gene name synonym)|uniprotkb:Peptidyl-prolyl cis-trans isomerase PTPA-1(gene name synonym)|uniprotkb:Phosphotyrosyl phosphatase activator 1(gene name synonym)	psi-mi:q8n7w2-2(display_long)|uniprotkb:C10orf30(gene name synonym)|uniprotkb:BEND7(gene name)|psi-mi:BEND7(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552620|imex:IM-24995-3726	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012113.1|sgd:S000001415|mint:P40454|dip:DIP-5663N|ensemblfungi:YIL153W(gene)|ensemblfungi:YIL153W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006914"(autophagy)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008160"(protein tyrosine phosphatase activator activity)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0043618"(regulation of transcription from RNA polymerase II promoter in response to stress)|interpro:IPR004327(Phosphotyrosyl phosphatase activator, PTPA)|interpro:IPR037218|interpro:IPR043170|rcsb pdb:2IXO|rcsb pdb:2IXP	ensembl:ENSG00000165626(gene)|ensembl:ENST00000378605(transcript)|intact:EBI-743382(isoform-parent)|uniprotkb:Q8N7W2-2(isoform-parent)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:It2q8WlpmvLEZ1fqpRF5Fypw9Q4559292	rogid:p6qrTn80hLyVU0W2Tvwn50Q4m5I9606	intact-crc:21955E46C28597DB|rigid:8uzaz0eS8i/AV8eTSZYTcOFuBWY	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8N7W2-2	uniprotkb:P38151	intact:EBI-10181188|ensembl:ENSP00000367868	intact:EBI-12968|uniprotkb:D6VQM8|ensemblfungi:YBR233W	psi-mi:q8n7w2-2(display_long)|uniprotkb:C10orf30(gene name synonym)|uniprotkb:BEND7(gene name)|psi-mi:BEND7(display_short)	psi-mi:pbp2_yeast(display_long)|uniprotkb:YBR1531(orf name)|uniprotkb:YBR233W(locus name)|uniprotkb:PBP2(gene name)|psi-mi:PBP2(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552632|imex:IM-24995-3729	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000165626(gene)|ensembl:ENST00000378605(transcript)|intact:EBI-743382(isoform-parent)|uniprotkb:Q8N7W2-2(isoform-parent)	sgd:S000000437|refseq:NP_009792.3|dip:DIP-4947N|ensemblfungi:YBR233W(gene)|ensemblfungi:YBR233W_mRNA(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0051252"(regulation of RNA metabolic process)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR036612	-	-	crc64:638846509BCE1840	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:p6qrTn80hLyVU0W2Tvwn50Q4m5I9606	rogid:zcN9K+pivnit4l3Cl75wfk5F4VI559292	intact-crc:75729DCEE1C06476|rigid:mnpGnz+q9xWMm9vKv1ViKcntT3M	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q04307	uniprotkb:Q8N7W2-2	intact:EBI-15858|uniprotkb:Q2VQW5|ensemblfungi:YDR045C|uniprotkb:D6VS33	intact:EBI-10181188|ensembl:ENSP00000367868	psi-mi:rpc10_yeast(display_long)|uniprotkb:RPC11(gene name)|psi-mi:RPC11(display_short)|uniprotkb:YDR045C(locus name)|uniprotkb:YD9609.01C(orf name)|uniprotkb:RNA polymerase III subunit C11(gene name synonym)|uniprotkb:DNA-directed RNA polymerases III 12.5 kDa polypeptide(gene name synonym)	psi-mi:q8n7w2-2(display_long)|uniprotkb:C10orf30(gene name synonym)|uniprotkb:BEND7(gene name)|psi-mi:BEND7(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552612|imex:IM-24995-3724	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YDR045C(gene)|refseq:NP_010330.1|sgd:S000002452|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006386"(termination of RNA polymerase III transcription)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042779"(tRNA 3'-trailer cleavage)|go:"GO:0042797"(tRNA transcription by RNA polymerase III)|interpro:IPR001222(Zinc finger, TFIIS-type)|interpro:IPR001529(DNA-directed RNA polymerase, M/15 kDa subunit)|interpro:IPR012164(DNA-directed RNA polymerase, subunit C11/M/9)|interpro:IPR019761|interpro:IPR034014|rcsb pdb:3QT1|ensemblfungi:YDR045C_mRNA(transcript)|rcsb pdb:5FJ8|rcsb pdb:5FJ9|rcsb pdb:5FJA|rcsb pdb:6CNB|rcsb pdb:6CNC|rcsb pdb:6CND|rcsb pdb:6CNF|rcsb pdb:6EU0|rcsb pdb:6EU2|rcsb pdb:6EU3|rcsb pdb:6F40|rcsb pdb:6F41|rcsb pdb:6F42|rcsb pdb:6F44|rcsb pdb:6TUT|reactome:R-SCE-76061|reactome:R-SCE-76066|rcsb pdb:6EU1|dip:DIP-887N|mint:Q04307	ensembl:ENSG00000165626(gene)|ensembl:ENST00000378605(transcript)|intact:EBI-743382(isoform-parent)|uniprotkb:Q8N7W2-2(isoform-parent)	-	crc64:E4AA802EC9F92230	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:G2fIQbptabHIUI224iPtTJF+dIs559292	rogid:p6qrTn80hLyVU0W2Tvwn50Q4m5I9606	intact-crc:2ECE123186B34BAC|rigid:9adlJDrnegjPAP7J4eGktnx2ZJI	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P32902	uniprotkb:Q8N6Y0	intact:EBI-16248|ensemblfungi:YHL004W|uniprotkb:D3DKR0	intact:EBI-739895|uniprotkb:Q8NBX7|uniprotkb:Q96KH3|uniprotkb:Q9BYI8|uniprotkb:A8K7L6|uniprotkb:B2RCR9|ensembl:ENSP00000252597	psi-mi:rt04_yeast(display_long)|uniprotkb:MRP4(gene name)|psi-mi:MRP4(display_short)|uniprotkb:MRP4A(gene name synonym)|uniprotkb:Mitochondrial small ribosomal subunit protein uS2m(gene name synonym)|uniprotkb:YHL004W(locus name)	psi-mi:usbp1_human(display_long)|uniprotkb:USHBP1(gene name)|psi-mi:USHBP1(display_short)|uniprotkb:MCC-2(gene name synonym)|uniprotkb:AIE-75-binding protein(gene name synonym)|uniprotkb:AIEBP(gene name synonym)|uniprotkb:MCC2(gene name synonym)|uniprotkb:Mutated in colon cancer protein 2(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552608|imex:IM-24995-3723	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YHL004W(gene)|ensemblfungi:YHL004W_mRNA(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR001865(Ribosomal protein S2)|interpro:IPR005706(Ribosomal protein S2, bacterial-type)|interpro:IPR018130|interpro:IPR023591|rcsb pdb:5MRC|rcsb pdb:5MRE|rcsb pdb:5MRF|refseq:NP_011859.1|sgd:S000000996|dip:DIP-5035N|mint:P32902	refseq:NP_001284632.1|refseq:NP_114147.2|refseq:NP_001308346.1|ensembl:ENSG00000130307(gene)|ensembl:ENST00000252597(transcript)|go:"GO:0030165"(PDZ domain binding)|interpro:IPR019536|interpro:IPR040171	-	crc64:81A1CB33134BC559	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:BlL3W6HUN+uAKF/AxwlV1zT5YZQ559292	rogid:vY1qx73Ju/z7WDu6k1kd10ZDVRo9606	intact-crc:2FA9F82AC475ADBA|rigid:UpZ7rQV1DYkju5zEWzt11XSJgZ0	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8N7W2-2	uniprotkb:Q12055	intact:EBI-10181188|ensembl:ENSP00000367868	intact:EBI-22197|uniprotkb:D6VRI5|uniprotkb:E9P8W4|ensemblfungi:YDL166C	psi-mi:q8n7w2-2(display_long)|uniprotkb:C10orf30(gene name synonym)|uniprotkb:BEND7(gene name)|psi-mi:BEND7(display_short)	psi-mi:kad6_yeast(display_long)|uniprotkb:FAP7(gene name)|psi-mi:FAP7(display_short)|uniprotkb:POS9-activating factor 7(gene name synonym)|uniprotkb:YDL166C(locus name)|uniprotkb:Dual activity adenylate kinase/ATPase(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552616|imex:IM-24995-3725	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000165626(gene)|ensembl:ENST00000378605(transcript)|intact:EBI-743382(isoform-parent)|uniprotkb:Q8N7W2-2(isoform-parent)	refseq:NP_010115.1|sgd:S000002325|reactome:R-SCE-499943|dip:DIP-4793N|ensemblfungi:YDL166C(gene)|ensemblfungi:YDL166C_mRNA(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0004017"(adenylate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0034599"(cellular response to oxidative stress)|interpro:IPR020618|interpro:IPR027417	-	-	crc64:836A25B0D7E2633C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:p6qrTn80hLyVU0W2Tvwn50Q4m5I9606	rogid:/hVE29n+kxI3CjMUlxtJxrvUpYk559292	intact-crc:8037D4EF6828E94D|rigid:tc2fv+VlLxFnsV55ohYeDNQErD8	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q12511	uniprotkb:Q8N9N5-2	intact:EBI-36488|uniprotkb:D6W2F1|ensemblfungi:YOR090C	intact:EBI-11524452|ensembl:ENSP00000347125	psi-mi:pdp1_yeast(display_long)|uniprotkb:PTC5(gene name)|psi-mi:PTC5(display_short)|uniprotkb:Phosphatase two C protein 5(gene name synonym)|uniprotkb:PPP1(gene name synonym)|uniprotkb:Protein phosphatase 2C homolog 5(gene name synonym)|uniprotkb:Protein phosphatase of PDH protein 1(gene name synonym)|uniprotkb:Pyruvate dehydrogenase complex phosphatase 1(gene name synonym)|uniprotkb:YOR3157C(orf name)|uniprotkb:YOR090C(locus name)	psi-mi:q8n9n5-2(display_long)|uniprotkb:BANP(gene name)|psi-mi:BANP(display_short)|uniprotkb:BEN domain-containing protein 1(gene name synonym)|uniprotkb:BEND1(gene name synonym)|uniprotkb:Btg3-associated nuclear protein(gene name synonym)|uniprotkb:SMAR1(gene name synonym)|uniprotkb:Scaffold/matrix-associated region-1-binding protein(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552660|imex:IM-24995-3736	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014733.1|sgd:S000005616|mint:Q12511|dip:DIP-6439N|ensemblfungi:YOR090C(gene)|ensemblfungi:YOR090C_mRNA(transcript)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0004741"("[pyruvate dehydrogenase (lipoamide)] phosphatase activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:1904184"(positive regulation of pyruvate dehydrogenase activity)|interpro:IPR000222(Protein phosphatase 2C,  manganese/magnesium aspartate binding site)|interpro:IPR001932(Protein phosphatase 2C-related)|interpro:IPR015655(Protein phosphatase 2C)|interpro:IPR036457	ensembl:ENSG00000172530(gene)|ensembl:ENST00000355022(transcript)|intact:EBI-744695(isoform-parent)|uniprotkb:Q8N9N5-2(isoform-parent)	-	crc64:07A5AF33FA72CC2A	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:AepMamITZgBeuBC3Gni6DMkg35E559292	rogid:ESe6iCAhvq+i57fQHz3rGyg6UOo9606	intact-crc:57F21352E0A782AF|rigid:LbM1zrUYsHvGH+eLkyJtoDtaJ8E	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8N9N5-2	uniprotkb:Q06011	intact:EBI-11524452|ensembl:ENSP00000347125	intact:EBI-36392|uniprotkb:D6VZ25|ensemblfungi:YLR390W	psi-mi:q8n9n5-2(display_long)|uniprotkb:BANP(gene name)|psi-mi:BANP(display_short)|uniprotkb:BEN domain-containing protein 1(gene name synonym)|uniprotkb:BEND1(gene name synonym)|uniprotkb:Btg3-associated nuclear protein(gene name synonym)|uniprotkb:SMAR1(gene name synonym)|uniprotkb:Scaffold/matrix-associated region-1-binding protein(gene name synonym)	psi-mi:ecm19_yeast(display_long)|uniprotkb:ECM19(gene name)|psi-mi:ECM19(display_short)|uniprotkb:Extracellular mutant protein 19(gene name synonym)|uniprotkb:YLR390W(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552656|imex:IM-24995-3735	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000172530(gene)|ensembl:ENST00000355022(transcript)|intact:EBI-744695(isoform-parent)|uniprotkb:Q8N9N5-2(isoform-parent)	sgd:S000004382|refseq:NP_013494.3|dip:DIP-8813N|ensemblfungi:YLR390W(gene)|ensemblfungi:YLR390W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0071555"(cell wall organization)	-	-	crc64:B469042AC2025AA7	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:ESe6iCAhvq+i57fQHz3rGyg6UOo9606	rogid:UBC9QbTkaTXXDvZdA/6/HJWDVqM559292	intact-crc:B7B98FCB07E1E201|rigid:XAelBa76R8A2YR1Ckv+C/lnQi1I	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q04599	uniprotkb:Q8N9N5-2	intact:EBI-38719|uniprotkb:D6VSA1|ensemblfungi:YDR116C	intact:EBI-11524452|ensembl:ENSP00000347125	psi-mi:rm01_yeast(display_long)|uniprotkb:MRPL1(gene name)|psi-mi:MRPL1(display_short)|uniprotkb:Mitochondrial large ribosomal subunit protein uL1m(gene name synonym)|uniprotkb:YD9727.11C(orf name)|uniprotkb:YDR116C(locus name)	psi-mi:q8n9n5-2(display_long)|uniprotkb:BANP(gene name)|psi-mi:BANP(display_short)|uniprotkb:BEN domain-containing protein 1(gene name synonym)|uniprotkb:BEND1(gene name synonym)|uniprotkb:Btg3-associated nuclear protein(gene name synonym)|uniprotkb:SMAR1(gene name synonym)|uniprotkb:Scaffold/matrix-associated region-1-binding protein(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552652|imex:IM-24995-3734	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010401.1|sgd:S000002523|mint:Q04599|dip:DIP-5223N|ensemblfungi:YDR116C(gene)|ensemblfungi:YDR116C_mRNA(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR002143(Ribosomal protein L1)|interpro:IPR005879(Ribosomal protein L1, mitochondrial)|interpro:IPR016095(Ribosomal protein L1, 3-layer alpha/beta-sandwich)|interpro:IPR023673|interpro:IPR023674|interpro:IPR028364	ensembl:ENSG00000172530(gene)|ensembl:ENST00000355022(transcript)|intact:EBI-744695(isoform-parent)|uniprotkb:Q8N9N5-2(isoform-parent)	-	crc64:59DB6C5D10421A77	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:Vco7wlmhTOETdBwIRgrjIdRR92w559292	rogid:ESe6iCAhvq+i57fQHz3rGyg6UOo9606	intact-crc:B6E7D9BAF9F0666E|rigid:p1xQkU70QRwfT53XY1ZT+tRdRTc	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8N7W2-2	uniprotkb:P25372	intact:EBI-10181188|ensembl:ENSP00000367868	intact:EBI-19616|uniprotkb:D6VR84|ensemblfungi:YCR083W	psi-mi:q8n7w2-2(display_long)|uniprotkb:C10orf30(gene name synonym)|uniprotkb:BEND7(gene name)|psi-mi:BEND7(display_short)	psi-mi:trx3_yeast(display_long)|uniprotkb:TRX3(gene name)|psi-mi:TRX3(display_short)|uniprotkb:YCR83W(orf name)|uniprotkb:YCR083W(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552636|imex:IM-24995-3730	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000165626(gene)|ensembl:ENST00000378605(transcript)|intact:EBI-743382(isoform-parent)|uniprotkb:Q8N7W2-2(isoform-parent)	interpro:IPR036249|refseq:NP_010006.1|sgd:S000000679|interpro:IPR017937|interpro:IPR013766(Thioredoxin domain)|rcsb pdb:2OE0|rcsb pdb:2OE1|rcsb pdb:2OE3|ensemblfungi:YCR083W(gene)|ensemblfungi:YCR083W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0015036"(disulfide oxidoreductase activity)|go:"GO:0034599"(cellular response to oxidative stress)|rcsb pdb:5YKW	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:p6qrTn80hLyVU0W2Tvwn50Q4m5I9606	rogid:g0xjGf9GvJRl8iv2qoT5tOs7jXI559292	intact-crc:0538E6DA448A193B|rigid:o0fB5iTlqwudH6QuYtl3LKu7IBE	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8N9N5-2	uniprotkb:P40455	intact:EBI-11524452|ensembl:ENSP00000347125	intact:EBI-25274|uniprotkb:D6VVD5|ensemblfungi:YIL152W	psi-mi:q8n9n5-2(display_long)|uniprotkb:BANP(gene name)|psi-mi:BANP(display_short)|uniprotkb:BEN domain-containing protein 1(gene name synonym)|uniprotkb:BEND1(gene name synonym)|uniprotkb:Btg3-associated nuclear protein(gene name synonym)|uniprotkb:SMAR1(gene name synonym)|uniprotkb:Scaffold/matrix-associated region-1-binding protein(gene name synonym)	psi-mi:yip2_yeast(display_long)|uniprotkb:YIL152W(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552644|imex:IM-24995-3732	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000172530(gene)|ensembl:ENST00000355022(transcript)|intact:EBI-744695(isoform-parent)|uniprotkb:Q8N9N5-2(isoform-parent)	sgd:S000001414|refseq:NP_012114.1|mint:P40455|dip:DIP-2047N|ensemblfungi:YIL152W(gene)|ensemblfungi:YIL152W_mRNA(transcript)	-	-	crc64:07550E3F491F53A8	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:ESe6iCAhvq+i57fQHz3rGyg6UOo9606	rogid:t5hCm1ck6kpFUxpEd8CsyLrHbEw559292	intact-crc:AB15584F3AD20EC2|rigid:Y6m8Umk009Rd1Pv4uhcYS7loBOg	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8N7W2-2	uniprotkb:P39518	intact:EBI-10181188|ensembl:ENSP00000367868	intact:EBI-10082|uniprotkb:D3DLR3|ensemblfungi:YER015W	psi-mi:q8n7w2-2(display_long)|uniprotkb:C10orf30(gene name synonym)|uniprotkb:BEND7(gene name)|psi-mi:BEND7(display_short)	psi-mi:lcf2_yeast(display_long)|uniprotkb:YER015W(locus name)|uniprotkb:FAA2(gene name)|psi-mi:FAA2(display_short)|uniprotkb:FAM1(gene name synonym)|uniprotkb:Long-chain acyl-CoA synthetase 2(gene name synonym)|uniprotkb:Fatty acid activator 2(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552640|imex:IM-24995-3731	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000165626(gene)|ensembl:ENST00000378605(transcript)|intact:EBI-743382(isoform-parent)|uniprotkb:Q8N7W2-2(isoform-parent)	sgd:S000000817|ensemblfungi:YER015W_mRNA(transcript)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0004467"(long-chain fatty acid-CoA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0015910"(long-chain fatty acid import into peroxisome)|go:"GO:0015916"(fatty-acyl-CoA transport)|go:"GO:0016020"(membrane)|go:"GO:0031956"(medium-chain fatty acid-CoA ligase activity)|go:"GO:0031957"(very long-chain fatty acid-CoA ligase activity)|go:"GO:0042760"(very long-chain fatty acid catabolic process)|go:"GO:0102391"(decanoate-CoA ligase activity)|ensemblfungi:YER015W(gene)|interpro:IPR020845|interpro:IPR000873(AMP-dependent synthetase and ligase)|reactome:R-SCE-75876|refseq:NP_010931.3|dip:DIP-6565N	-	-	crc64:1E023C18682805BC	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:p6qrTn80hLyVU0W2Tvwn50Q4m5I9606	rogid:N0W+wPvCsl01y0k8hJZ156LztOo559292	intact-crc:D22A7606101535AF|rigid:EjK37wZoiPafiy8nv3vpz9zYSac	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8N9N5-2	uniprotkb:P25566	intact:EBI-11524452|ensembl:ENSP00000347125	intact:EBI-21713|uniprotkb:D6VQY2|ensemblfungi:YCL033C	psi-mi:q8n9n5-2(display_long)|uniprotkb:BANP(gene name)|psi-mi:BANP(display_short)|uniprotkb:BEN domain-containing protein 1(gene name synonym)|uniprotkb:BEND1(gene name synonym)|uniprotkb:Btg3-associated nuclear protein(gene name synonym)|uniprotkb:SMAR1(gene name synonym)|uniprotkb:Scaffold/matrix-associated region-1-binding protein(gene name synonym)	psi-mi:mxr2_yeast(display_long)|uniprotkb:YCL033C(locus name)|uniprotkb:YCL33C(orf name)|uniprotkb:MXR2(gene name)|psi-mi:MXR2(display_short)|uniprotkb:MSRB(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552648|imex:IM-24995-3733	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000172530(gene)|ensembl:ENST00000355022(transcript)|intact:EBI-744695(isoform-parent)|uniprotkb:Q8N9N5-2(isoform-parent)	refseq:NP_009897.1|sgd:S000000538|dip:DIP-4861N|ensemblfungi:YCL033C(gene)|ensemblfungi:YCL033C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0030091"(protein repair)|go:"GO:0033743"("peptide-methionine (R)-S-oxide reductase activity")|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0046872"(metal ion binding)|interpro:IPR002579(Methionine sulphoxide reductase B)|interpro:IPR011057(Mss4-like)|interpro:IPR028427	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:ESe6iCAhvq+i57fQHz3rGyg6UOo9606	rogid:iqa3p6vw9Ah3pxugESw1TdFd6bU559292	intact-crc:1AEADC1F5EC29A48|rigid:QDKId1BrMktzR5nKsR1jWENa2Lk	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P35192	uniprotkb:Q8N9N5-2	intact:EBI-10346|ensemblfungi:YMR021C|uniprotkb:D6VZJ5|uniprotkb:E9P8Z5	intact:EBI-11524452|ensembl:ENSP00000347125	psi-mi:mac1_yeast(display_long)|uniprotkb:MAC1(gene name)|psi-mi:MAC1(display_short)|uniprotkb:CUA1(gene name synonym)|uniprotkb:YMR021C(locus name)|uniprotkb:YM9711.11C(orf name)	psi-mi:q8n9n5-2(display_long)|uniprotkb:BANP(gene name)|psi-mi:BANP(display_short)|uniprotkb:BEN domain-containing protein 1(gene name synonym)|uniprotkb:BEND1(gene name synonym)|uniprotkb:Btg3-associated nuclear protein(gene name synonym)|uniprotkb:SMAR1(gene name synonym)|uniprotkb:Scaffold/matrix-associated region-1-binding protein(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552680|imex:IM-24995-3741	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013734.1|sgd:S000004623|ensemblfungi:YMR021C(gene)|ensemblfungi:YMR021C_mRNA(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005507"(copper ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0006878"(cellular copper ion homeostasis)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR036395|interpro:IPR001083(Copper fist DNA-binding)|dip:DIP-4851N	ensembl:ENSG00000172530(gene)|ensembl:ENST00000355022(transcript)|intact:EBI-744695(isoform-parent)|uniprotkb:Q8N9N5-2(isoform-parent)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:qm/hIB5eRjjEZv9H+Zng34N5ops559292	rogid:ESe6iCAhvq+i57fQHz3rGyg6UOo9606	intact-crc:7C258EA8E575FEA7|rigid:Ton7BCxl/TrkXRCpHGyZ531A/dM	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8N9N5-2	uniprotkb:P25372	intact:EBI-11524452|ensembl:ENSP00000347125	intact:EBI-19616|uniprotkb:D6VR84|ensemblfungi:YCR083W	psi-mi:q8n9n5-2(display_long)|uniprotkb:BANP(gene name)|psi-mi:BANP(display_short)|uniprotkb:BEN domain-containing protein 1(gene name synonym)|uniprotkb:BEND1(gene name synonym)|uniprotkb:Btg3-associated nuclear protein(gene name synonym)|uniprotkb:SMAR1(gene name synonym)|uniprotkb:Scaffold/matrix-associated region-1-binding protein(gene name synonym)	psi-mi:trx3_yeast(display_long)|uniprotkb:TRX3(gene name)|psi-mi:TRX3(display_short)|uniprotkb:YCR83W(orf name)|uniprotkb:YCR083W(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552676|imex:IM-24995-3740	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000172530(gene)|ensembl:ENST00000355022(transcript)|intact:EBI-744695(isoform-parent)|uniprotkb:Q8N9N5-2(isoform-parent)	interpro:IPR036249|refseq:NP_010006.1|sgd:S000000679|interpro:IPR017937|interpro:IPR013766(Thioredoxin domain)|rcsb pdb:2OE0|rcsb pdb:2OE1|rcsb pdb:2OE3|ensemblfungi:YCR083W(gene)|ensemblfungi:YCR083W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0015036"(disulfide oxidoreductase activity)|go:"GO:0034599"(cellular response to oxidative stress)|rcsb pdb:5YKW	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:ESe6iCAhvq+i57fQHz3rGyg6UOo9606	rogid:g0xjGf9GvJRl8iv2qoT5tOs7jXI559292	intact-crc:D4A2C64B434C7F4D|rigid:D2t9mdT178XNXvZzowu3vAPVZPE	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8N9N5-2	uniprotkb:P35184	intact:EBI-11524452|ensembl:ENSP00000347125	intact:EBI-17971|uniprotkb:D6VVU2|ensemblfungi:YIR012W	psi-mi:q8n9n5-2(display_long)|uniprotkb:BANP(gene name)|psi-mi:BANP(display_short)|uniprotkb:BEN domain-containing protein 1(gene name synonym)|uniprotkb:BEND1(gene name synonym)|uniprotkb:Btg3-associated nuclear protein(gene name synonym)|uniprotkb:SMAR1(gene name synonym)|uniprotkb:Scaffold/matrix-associated region-1-binding protein(gene name synonym)	psi-mi:sqt1_yeast(display_long)|uniprotkb:YIB12W(orf name)|uniprotkb:YIR012W(locus name)|uniprotkb:SQT1(gene name)|psi-mi:SQT1(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552664|imex:IM-24995-3737	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000172530(gene)|ensembl:ENST00000355022(transcript)|intact:EBI-744695(isoform-parent)|uniprotkb:Q8N9N5-2(isoform-parent)	refseq:NP_012277.1|sgd:S000001451|ensemblfungi:YIR012W_mRNA(transcript)|ensemblfungi:YIR012W(gene)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|rcsb pdb:4ZOV|rcsb pdb:4ZOX|rcsb pdb:5AMS|dip:DIP-2508N|mint:P35184	-	-	crc64:981D566076B0C881	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:ESe6iCAhvq+i57fQHz3rGyg6UOo9606	rogid:u/Q5uAjR85ZD3op0nHiN20IVCLY559292	intact-crc:FBCF9113799F48D9|rigid:kNLcFGB1nOnQGr7O4/Jatl49fLg	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P39724	uniprotkb:Q8N9N5-2	intact:EBI-2343154|uniprotkb:D6VPH0|ensemblfungi:YAL046C	intact:EBI-11524452|ensembl:ENSP00000347125	psi-mi:bol3_yeast(display_long)|uniprotkb:BOL3(gene name)|psi-mi:BOL3(display_short)|uniprotkb:AIM1(gene name synonym)|uniprotkb:Altered inheritance of mitochondria protein 1(gene name synonym)|uniprotkb:YAL046C(locus name)	psi-mi:q8n9n5-2(display_long)|uniprotkb:BANP(gene name)|psi-mi:BANP(display_short)|uniprotkb:BEN domain-containing protein 1(gene name synonym)|uniprotkb:BEND1(gene name synonym)|uniprotkb:Btg3-associated nuclear protein(gene name synonym)|uniprotkb:SMAR1(gene name synonym)|uniprotkb:Scaffold/matrix-associated region-1-binding protein(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552668|imex:IM-24995-3738	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009353.1|sgd:S000000044|interpro:IPR002634(BolA-like protein)|interpro:IPR036065|mint:P39724|ensemblfungi:YAL046C(gene)|ensemblfungi:YAL046C_mRNA(transcript)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0106035"(protein maturation by [4Fe-4S] cluster transfer)	ensembl:ENSG00000172530(gene)|ensembl:ENST00000355022(transcript)|intact:EBI-744695(isoform-parent)|uniprotkb:Q8N9N5-2(isoform-parent)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:MLrW6Iu4YKXf87O1cyx5bY03VdE559292	rogid:ESe6iCAhvq+i57fQHz3rGyg6UOo9606	intact-crc:EE87C9A20C85DA2D|rigid:ccEvLtoXDVwSCelr9mseh0wQBAY	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8N9N5-2	uniprotkb:Q10740	intact:EBI-11524452|ensembl:ENSP00000347125	intact:EBI-10175|uniprotkb:D6W1D4|ensemblfungi:YNL045W	psi-mi:q8n9n5-2(display_long)|uniprotkb:BANP(gene name)|psi-mi:BANP(display_short)|uniprotkb:BEN domain-containing protein 1(gene name synonym)|uniprotkb:BEND1(gene name synonym)|uniprotkb:Btg3-associated nuclear protein(gene name synonym)|uniprotkb:SMAR1(gene name synonym)|uniprotkb:Scaffold/matrix-associated region-1-binding protein(gene name synonym)	psi-mi:lkha4_yeast(display_long)|uniprotkb:LAP2(gene name)|psi-mi:LAP2(display_short)|uniprotkb:Epoxide hydrolase(gene name synonym)|uniprotkb:Leucyl aminopeptidase yscIV(gene name synonym)|uniprotkb:Leukotriene A-4 hydrolase homolog(gene name synonym)|uniprotkb:N2535(orf name)|uniprotkb:YNL045W(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552672|imex:IM-24995-3739	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000172530(gene)|ensembl:ENST00000355022(transcript)|intact:EBI-744695(isoform-parent)|uniprotkb:Q8N9N5-2(isoform-parent)	refseq:NP_014353.1|sgd:S000004990|go:"GO:0008270"(zinc ion binding)|go:"GO:0030163"(protein catabolic process)|go:"GO:0043171"(peptide catabolic process)|go:"GO:0044255"(cellular lipid metabolic process)|ensemblfungi:YNL045W(gene)|ensemblfungi:YNL045W_mRNA(transcript)|go:"GO:0004177"(aminopeptidase activity)|go:"GO:0004301"(epoxide hydrolase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|interpro:IPR001930(Peptidase M1, membrane alanine aminopeptidase)|go:"GO:0005829"(cytosol)|interpro:IPR012777(Leukotriene A-4 hydrolase/aminopeptidase)|go:"GO:0008237"(metallopeptidase activity)|interpro:IPR014782(Peptidase M1, membrane alanine aminopeptidase, N-terminal)|interpro:IPR015211(Peptidase M1, leukotriene A4 hydrolase, aminopeptidase C-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027268|interpro:IPR034015|interpro:IPR038502|interpro:IPR042097|rcsb pdb:2XPZ|rcsb pdb:2XQ0|reactome:R-SCE-2142691|reactome:R-SCE-6798695|reactome:R-SCE-9018676|reactome:R-SCE-9018681|reactome:R-SCE-9018896|reactome:R-SCE-9020265|rcsb pdb:2XPY|reactome:R-SCE-9023661|dip:DIP-4371N|mint:Q10740	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:ESe6iCAhvq+i57fQHz3rGyg6UOo9606	rogid:CqwX8n+boaHaneIOt/jhsAJngF8559292	intact-crc:938E05FB85DAD768|rigid:WO1wZSHxzAEB5Qw2g2FiUe0x0xk	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P32464	uniprotkb:Q8NA61-2	intact:EBI-8859|ensemblfungi:YKL189W|uniprotkb:D6VX11	intact:EBI-11524851|ensembl:ENSP00000368249|ensembl:ENSP00000480148	psi-mi:hym1_yeast(display_long)|uniprotkb:YKL189W(locus name)|uniprotkb:HYM1(gene name)|psi-mi:HYM1(display_short)	psi-mi:q8na61-2(display_long)|uniprotkb:CBY2(gene name)|psi-mi:CBY2(display_short)|uniprotkb:SPERT(gene name synonym)|uniprotkb:Spermatid-associated protein(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552708|imex:IM-24995-3748	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YKL189W(gene)|ensemblfungi:YKL189W_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0000920"(septum digestion after cytokinesis)|go:"GO:0005933"(cellular bud)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007118"(budding cell apical bud growth)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043332"(mating projection tip)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0044732"(mitotic spindle pole body)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013878(Mo25-like)|interpro:IPR016024(Armadillo-type fold)|reactome:R-SCE-6798695|refseq:NP_012732.1|sgd:S000001672|mint:P32464|dip:DIP-5425N	intact:EBI-741724(isoform-parent)|ensembl:ENSG00000174015(gene)|ensembl:ENST00000378966(transcript)|ensembl:ENST00000610924(transcript)|uniprotkb:Q8NA61-2(isoform-parent)	-	crc64:F48860754C892BA9	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:pOlQFFuYgFzmqf3ZGUVkBj9h7Uc559292	rogid:SogYcXGGMYRYzB9xKC5o0pEtsDs9606	intact-crc:485F6DDD3E73C536|rigid:C9ytOIqS0AwNc/ow8UyMDpknYcQ	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P32902	uniprotkb:Q8NA61-2	intact:EBI-16248|ensemblfungi:YHL004W|uniprotkb:D3DKR0	intact:EBI-11524851|ensembl:ENSP00000368249|ensembl:ENSP00000480148	psi-mi:rt04_yeast(display_long)|uniprotkb:MRP4(gene name)|psi-mi:MRP4(display_short)|uniprotkb:MRP4A(gene name synonym)|uniprotkb:Mitochondrial small ribosomal subunit protein uS2m(gene name synonym)|uniprotkb:YHL004W(locus name)	psi-mi:q8na61-2(display_long)|uniprotkb:CBY2(gene name)|psi-mi:CBY2(display_short)|uniprotkb:SPERT(gene name synonym)|uniprotkb:Spermatid-associated protein(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552704|imex:IM-24995-3747	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YHL004W(gene)|ensemblfungi:YHL004W_mRNA(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR001865(Ribosomal protein S2)|interpro:IPR005706(Ribosomal protein S2, bacterial-type)|interpro:IPR018130|interpro:IPR023591|rcsb pdb:5MRC|rcsb pdb:5MRE|rcsb pdb:5MRF|refseq:NP_011859.1|sgd:S000000996|dip:DIP-5035N|mint:P32902	intact:EBI-741724(isoform-parent)|ensembl:ENSG00000174015(gene)|ensembl:ENST00000378966(transcript)|ensembl:ENST00000610924(transcript)|uniprotkb:Q8NA61-2(isoform-parent)	-	crc64:81A1CB33134BC559	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:BlL3W6HUN+uAKF/AxwlV1zT5YZQ559292	rogid:SogYcXGGMYRYzB9xKC5o0pEtsDs9606	intact-crc:B7E848EDA57F51C4|rigid:efXubap58mIr57EWgtd3RkV3SoM	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8NA61-2	uniprotkb:Q07732	intact:EBI-11524851|ensembl:ENSP00000368249|ensembl:ENSP00000480148	intact:EBI-33406|ensemblfungi:YDL239C|uniprotkb:D6VRB7	psi-mi:q8na61-2(display_long)|uniprotkb:CBY2(gene name)|psi-mi:CBY2(display_short)|uniprotkb:SPERT(gene name synonym)|uniprotkb:Spermatid-associated protein(gene name synonym)	psi-mi:ady3_yeast(display_long)|uniprotkb:YDL239C(locus name)|uniprotkb:ADY3(gene name)|psi-mi:ADY3(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552700|imex:IM-24995-3746	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-741724(isoform-parent)|ensembl:ENSG00000174015(gene)|ensembl:ENST00000378966(transcript)|ensembl:ENST00000610924(transcript)|uniprotkb:Q8NA61-2(isoform-parent)	refseq:NP_010042.2|sgd:S000002398|ensemblfungi:YDL239C(gene)|ensemblfungi:YDL239C_mRNA(transcript)|go:"GO:0000001"(mitochondrion inheritance)|go:"GO:0005628"(prospore membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0030435"(sporulation resulting in formation of a cellular spore)|go:"GO:0030476"(ascospore wall assembly)|go:"GO:0032120"(ascospore-type prospore membrane formation)|go:"GO:0051301"(cell division)|go:"GO:0070056"(prospore membrane leading edge)|interpro:IPR021750|mint:Q07732|dip:DIP-1811N	-	-	crc64:46F17474F30FD3D9	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:SogYcXGGMYRYzB9xKC5o0pEtsDs9606	rogid:Cmac2NLDdbBzVKnJfFricfeeX24559292	intact-crc:2E423F7C10CADEE6|rigid:jaZwkCeZ60vDm4aVh1qzmjV6mYk	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q06892	uniprotkb:Q8N9N5-2	intact:EBI-13701|uniprotkb:Q08928|uniprotkb:D6W3I1|ensemblfungi:YPL188W	intact:EBI-11524452|ensembl:ENSP00000347125	psi-mi:pos5_yeast(display_long)|uniprotkb:POS5(gene name)|psi-mi:POS5(display_short)|uniprotkb:YPL188W(locus name)	psi-mi:q8n9n5-2(display_long)|uniprotkb:BANP(gene name)|psi-mi:BANP(display_short)|uniprotkb:BEN domain-containing protein 1(gene name synonym)|uniprotkb:BEND1(gene name synonym)|uniprotkb:Btg3-associated nuclear protein(gene name synonym)|uniprotkb:SMAR1(gene name synonym)|uniprotkb:Scaffold/matrix-associated region-1-binding protein(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552684|imex:IM-24995-3742	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000006109|refseq:NP_015136.1|ensemblfungi:YPL188W(gene)|ensemblfungi:YPL188W_mRNA(transcript)|go:"GO:0003951"(NAD+ kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006741"(NADP biosynthetic process)|go:"GO:0019674"(NAD metabolic process)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0042736"(NADH kinase activity)|interpro:IPR002504(ATP-NAD/AcoX kinase)|interpro:IPR016064(ATP-NAD kinase, PpnK-type)|interpro:IPR017437(ATP-NAD kinase, PpnK-type, all-beta)|interpro:IPR017438(ATP-NAD kinase, PpnK-type, alpha/beta)|rcsb pdb:3AFO|dip:DIP-5503N	ensembl:ENSG00000172530(gene)|ensembl:ENST00000355022(transcript)|intact:EBI-744695(isoform-parent)|uniprotkb:Q8N9N5-2(isoform-parent)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:4n8TcpxeCYBUCHDHMqmxXeNsiGg559292	rogid:ESe6iCAhvq+i57fQHz3rGyg6UOo9606	intact-crc:68D15A6C59D0762D|rigid:fkIWPJt/JzO5lZHgnnu/7NAaj7s	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8NA61-2	uniprotkb:P38340	intact:EBI-11524851|ensembl:ENSP00000368249|ensembl:ENSP00000480148	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:q8na61-2(display_long)|uniprotkb:CBY2(gene name)|psi-mi:CBY2(display_short)|uniprotkb:SPERT(gene name synonym)|uniprotkb:Spermatid-associated protein(gene name synonym)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552692|imex:IM-24995-3744	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-741724(isoform-parent)|ensembl:ENSG00000174015(gene)|ensembl:ENST00000378966(transcript)|ensembl:ENST00000610924(transcript)|uniprotkb:Q8NA61-2(isoform-parent)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F	-	-	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:SogYcXGGMYRYzB9xKC5o0pEtsDs9606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:7CCD55ADBF530825|rigid:NhAM0HIjA6aSDU1k4mqFLCknSvI	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8N9N5-2	uniprotkb:Q12329	intact:EBI-11524452|ensembl:ENSP00000347125	intact:EBI-8571|uniprotkb:D6VSF3|ensemblfungi:YDR171W	psi-mi:q8n9n5-2(display_long)|uniprotkb:BANP(gene name)|psi-mi:BANP(display_short)|uniprotkb:BEN domain-containing protein 1(gene name synonym)|uniprotkb:BEND1(gene name synonym)|uniprotkb:Btg3-associated nuclear protein(gene name synonym)|uniprotkb:SMAR1(gene name synonym)|uniprotkb:Scaffold/matrix-associated region-1-binding protein(gene name synonym)	psi-mi:hsp42_yeast(display_long)|uniprotkb:HSP42(gene name)|psi-mi:HSP42(display_short)|uniprotkb:YDR171W(locus name)|uniprotkb:YD9395.04(orf name)|uniprotkb:42 kDa heat shock protein(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552688|imex:IM-24995-3743	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000172530(gene)|ensembl:ENST00000355022(transcript)|intact:EBI-744695(isoform-parent)|uniprotkb:Q8N9N5-2(isoform-parent)	refseq:NP_010456.1|sgd:S000002578|mint:Q12329|dip:DIP-2515N|ensemblfungi:YDR171W(gene)|ensemblfungi:YDR171W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0009408"(response to heat)|go:"GO:0009651"(response to salt stress)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043621"(protein self-association)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0140311"(protein sequestering activity)|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR031107	-	-	crc64:DF353A76493E3CE6	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:ESe6iCAhvq+i57fQHz3rGyg6UOo9606	rogid:izvrv04fA3zcBqTeUeHD/erKGf4559292	intact-crc:04EB6AAE65EA3D68|rigid:qfKsJw/YTjkS/vwRcAEuCJNyM8o	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P26448	uniprotkb:Q8NA61-2	intact:EBI-3824|uniprotkb:D6VZN0|ensemblfungi:YMR055C	intact:EBI-11524851|ensembl:ENSP00000368249|ensembl:ENSP00000480148	psi-mi:bub2_yeast(display_long)|uniprotkb:BUB2(gene name)|psi-mi:BUB2(display_short)|uniprotkb:YMR055C(locus name)|uniprotkb:YM9796.08C(orf name)|uniprotkb:Cell cycle arrest protein BUB2(gene name synonym)	psi-mi:q8na61-2(display_long)|uniprotkb:CBY2(gene name)|psi-mi:CBY2(display_short)|uniprotkb:SPERT(gene name synonym)|uniprotkb:Spermatid-associated protein(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552696|imex:IM-24995-3745	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013771.1|sgd:S000004659|dip:DIP-1215N|mint:P26448|ensemblfungi:YMR055C(gene)|ensemblfungi:YMR055C_mRNA(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0031030"(negative regulation of septation initiation signaling)|go:"GO:0031578"(mitotic spindle orientation checkpoint signaling)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0051301"(cell division)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:1902543"(negative regulation of protein localization to mitotic spindle pole body)|go:"GO:1990334"(Bfa1-Bub2 complex)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR035969	intact:EBI-741724(isoform-parent)|ensembl:ENSG00000174015(gene)|ensembl:ENST00000378966(transcript)|ensembl:ENST00000610924(transcript)|uniprotkb:Q8NA61-2(isoform-parent)	-	crc64:A1DDBFB548E81EA3	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:+03m4HOOcKjpSjqpEZ8wCgD2Egc559292	rogid:SogYcXGGMYRYzB9xKC5o0pEtsDs9606	intact-crc:C0D5D2CABDBE407B|rigid:aQWoQmRaxtbCXfezUSu0zlJ/56g	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q04307	uniprotkb:Q8ND30	intact:EBI-15858|uniprotkb:Q2VQW5|ensemblfungi:YDR045C|uniprotkb:D6VS33	intact:EBI-744056|uniprotkb:O75337|uniprotkb:Q8WW26|intact:EBI-28975311|uniprotkb:B7Z433|uniprotkb:E9PK77|ensembl:ENSP00000299492	psi-mi:rpc10_yeast(display_long)|uniprotkb:RPC11(gene name)|psi-mi:RPC11(display_short)|uniprotkb:YDR045C(locus name)|uniprotkb:YD9609.01C(orf name)|uniprotkb:RNA polymerase III subunit C11(gene name synonym)|uniprotkb:DNA-directed RNA polymerases III 12.5 kDa polypeptide(gene name synonym)	psi-mi:lipb2_human(display_long)|uniprotkb:Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 2(gene name synonym)|uniprotkb:PPFIBP2(gene name)|psi-mi:PPFIBP2(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552736|imex:IM-24995-3755	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YDR045C(gene)|refseq:NP_010330.1|sgd:S000002452|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006386"(termination of RNA polymerase III transcription)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042779"(tRNA 3'-trailer cleavage)|go:"GO:0042797"(tRNA transcription by RNA polymerase III)|interpro:IPR001222(Zinc finger, TFIIS-type)|interpro:IPR001529(DNA-directed RNA polymerase, M/15 kDa subunit)|interpro:IPR012164(DNA-directed RNA polymerase, subunit C11/M/9)|interpro:IPR019761|interpro:IPR034014|rcsb pdb:3QT1|ensemblfungi:YDR045C_mRNA(transcript)|rcsb pdb:5FJ8|rcsb pdb:5FJ9|rcsb pdb:5FJA|rcsb pdb:6CNB|rcsb pdb:6CNC|rcsb pdb:6CND|rcsb pdb:6CNF|rcsb pdb:6EU0|rcsb pdb:6EU2|rcsb pdb:6EU3|rcsb pdb:6F40|rcsb pdb:6F41|rcsb pdb:6F42|rcsb pdb:6F44|rcsb pdb:6TUT|reactome:R-SCE-76061|reactome:R-SCE-76066|rcsb pdb:6EU1|dip:DIP-887N|mint:Q04307	refseq:NP_003612.2|ensembl:ENSP00000299492|ensembl:ENST00000528883|ensembl:ENSP00000435469|ensembl:ENST00000530181|ensembl:ENSP00000437321|refseq:NP_001243497.1|refseq:XP_016873932.1|dip:DIP-42373N|ensembl:ENSG00000166387(gene)|ensembl:ENST00000299492(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0042802"(identical protein binding)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0050808"(synapse organization)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR029515|interpro:IPR030435|interpro:IPR037617|interpro:IPR037618|interpro:IPR037619|mint:Q8ND30|rcsb pdb:3QH9|reactome:R-HSA-388844	-	crc64:E4AA802EC9F92230	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:G2fIQbptabHIUI224iPtTJF+dIs559292	rogid:36bMLWHJuGN5eItyc1HvhoLonZA9606	intact-crc:619A23BAD26A9167|rigid:Q9dj5jef7/lx/22Iu6UUYIJH55M	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P32502	uniprotkb:Q8NA82	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	intact:EBI-2341554|uniprotkb:D3DU09|uniprotkb:Q8N7Z7|uniprotkb:Q8IYS7|ensembl:ENSP00000311496|ensembl:ENSP00000416177	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:marha_human(display_long)|uniprotkb:MARCHF10(gene name)|psi-mi:MARCHF10(display_short)|uniprotkb:MARCH10(gene name synonym)|uniprotkb:Membrane-associated RING finger protein 10(gene name synonym)|uniprotkb:Membrane-associated RING-CH protein X(gene name synonym)|uniprotkb:RING finger protein 190(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase MARCHF10(gene name synonym)|uniprotkb:RNF190(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552732|imex:IM-24995-3754	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731	refseq:NP_001094345.1|refseq:NP_689811.2|refseq:NP_001275708.1|refseq:NP_001275709.1|ensembl:ENSG00000173838(gene)|ensembl:ENST00000311269(transcript)|ensembl:ENST00000456609(transcript)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016740"(transferase activity)|interpro:IPR011016(Zinc finger, variant RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR042583	-	crc64:A5409FAF1594854C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	rogid:xYNhVYIVxXneNrLbdaSO0uTK9l89606	intact-crc:A2433DF581542840|rigid:3K6aRt9u5yZ2AdstYQGOqazRuOY	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8NA61-2	uniprotkb:P29703	intact:EBI-11524851|ensembl:ENSP00000368249|ensembl:ENSP00000480148	intact:EBI-14814|uniprotkb:D6VXR6|ensemblfungi:YKL019W	psi-mi:q8na61-2(display_long)|uniprotkb:CBY2(gene name)|psi-mi:CBY2(display_short)|uniprotkb:SPERT(gene name synonym)|uniprotkb:Spermatid-associated protein(gene name synonym)	psi-mi:fnta_yeast(display_long)|uniprotkb:YKL019W(locus name)|uniprotkb:RAM2(gene name)|psi-mi:RAM2(display_short)|uniprotkb:CAAX farnesyltransferase subunit alpha(gene name synonym)|uniprotkb:Ras proteins prenyltransferase subunit alpha(gene name synonym)|uniprotkb:FTase-alpha(gene name synonym)|uniprotkb:Type I protein geranyl-geranyltransferase subunit alpha(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552728|imex:IM-24995-3753	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-741724(isoform-parent)|ensembl:ENSG00000174015(gene)|ensembl:ENST00000378966(transcript)|ensembl:ENST00000610924(transcript)|uniprotkb:Q8NA61-2(isoform-parent)	sgd:S000001502|refseq:NP_012906.3|go:"GO:0004662"(CAAX-protein geranylgeranyltransferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005953"(CAAX-protein geranylgeranyltransferase complex)|go:"GO:0005965"(protein farnesyltransferase complex)|go:"GO:0007323"(peptide pheromone maturation)|go:"GO:0018343"(protein farnesylation)|go:"GO:0018344"(protein geranylgeranylation)|interpro:IPR002088(Protein prenyltransferase, alpha subunit)|reactome:R-SCE-9648002|ensemblfungi:YKL019W(gene)|ensemblfungi:YKL019W_mRNA(transcript)|go:"GO:0004660"(protein farnesyltransferase activity)|go:"GO:0004661"(protein geranylgeranyltransferase activity)|dip:DIP-1233N|mint:P29703	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:SogYcXGGMYRYzB9xKC5o0pEtsDs9606	rogid:u2rtpSuSW9Zd8LHWmniip7r5Ycs559292	intact-crc:3C212EA3FA22A590|rigid:i4d4cxUdwD81HyA2LjGD4Qevni8	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8NA61-2	uniprotkb:P47041	intact:EBI-11524851|ensembl:ENSP00000368249|ensembl:ENSP00000480148	intact:EBI-25889|uniprotkb:D6VWC4|ensemblfungi:YJL058C	psi-mi:q8na61-2(display_long)|uniprotkb:CBY2(gene name)|psi-mi:CBY2(display_short)|uniprotkb:SPERT(gene name synonym)|uniprotkb:Spermatid-associated protein(gene name synonym)	psi-mi:bit61_yeast(display_long)|uniprotkb:YJL058C(locus name)|uniprotkb:J1141(orf name)|uniprotkb:61 kDa binding partner of TOR2 protein(gene name synonym)|uniprotkb:BIT61(gene name)|psi-mi:BIT61(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552712|imex:IM-24995-3749	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-741724(isoform-parent)|ensembl:ENSG00000174015(gene)|ensembl:ENST00000378966(transcript)|ensembl:ENST00000610924(transcript)|uniprotkb:Q8NA61-2(isoform-parent)	refseq:NP_012477.1|sgd:S000003594|dip:DIP-1444N|reactome:R-SCE-1257604|reactome:R-SCE-389357|reactome:R-SCE-5218920|ensemblfungi:YJL058C(gene)|ensemblfungi:YJL058C_mRNA(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005737"(cytoplasm)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0031932"(TORC2 complex)|go:"GO:0038203"(TORC2 signaling)|go:"GO:0071944"(cell periphery)|interpro:IPR013745(HbrB-like)|reactome:R-SCE-6804757	-	-	crc64:99F0F96840311F4B	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:SogYcXGGMYRYzB9xKC5o0pEtsDs9606	rogid:H+zcKwbWL90wsmvD9TfWYmEbRwM559292	intact-crc:E8E13EB413099533|rigid:sLZfmeAyOhjxlAPvkl23LA8ehaE	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P48232	uniprotkb:Q8NA61-2	intact:EBI-28775|uniprotkb:D6W193|ensemblfungi:YNL086W	intact:EBI-11524851|ensembl:ENSP00000368249|ensembl:ENSP00000480148	psi-mi:snapn_yeast(display_long)|uniprotkb:YNL086W(locus name)|uniprotkb:N2254(orf name)|uniprotkb:SNN1(gene name)|psi-mi:SNN1(display_short)|uniprotkb:SNAPIN-like protein 1(gene name synonym)	psi-mi:q8na61-2(display_long)|uniprotkb:CBY2(gene name)|psi-mi:CBY2(display_short)|uniprotkb:SPERT(gene name synonym)|uniprotkb:Spermatid-associated protein(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552720|imex:IM-24995-3751	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014313.1|sgd:S000005030|dip:DIP-1188N|mint:P48232|ensemblfungi:YNL086W(gene)|ensemblfungi:YNL086W_mRNA(transcript)|go:"GO:0005768"(endosome)|go:"GO:0007032"(endosome organization)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0032880"(regulation of protein localization)	intact:EBI-741724(isoform-parent)|ensembl:ENSG00000174015(gene)|ensembl:ENST00000378966(transcript)|ensembl:ENST00000610924(transcript)|uniprotkb:Q8NA61-2(isoform-parent)	-	crc64:33200D2F0F729DA1	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:XCPaHuGC9oKD/3W0gY5ZY8jKtFs559292	rogid:SogYcXGGMYRYzB9xKC5o0pEtsDs9606	intact-crc:D8913549E16BDE81|rigid:92+xr8GGy4qpJmxzQhTfRNYxDWE	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8NA61-2	uniprotkb:P40454	intact:EBI-11524851|ensembl:ENSP00000368249|ensembl:ENSP00000480148	intact:EBI-25278|uniprotkb:D6VVD4|ensemblfungi:YIL153W	psi-mi:q8na61-2(display_long)|uniprotkb:CBY2(gene name)|psi-mi:CBY2(display_short)|uniprotkb:SPERT(gene name synonym)|uniprotkb:Spermatid-associated protein(gene name synonym)	psi-mi:ptpa1_yeast(display_long)|uniprotkb:YIL153W(locus name)|uniprotkb:RRD1(gene name)|psi-mi:RRD1(display_short)|uniprotkb:NCS1(gene name synonym)|uniprotkb:YPA1(gene name synonym)|uniprotkb:Peptidyl-prolyl cis-trans isomerase PTPA-1(gene name synonym)|uniprotkb:Phosphotyrosyl phosphatase activator 1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552716|imex:IM-24995-3750	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-741724(isoform-parent)|ensembl:ENSG00000174015(gene)|ensembl:ENST00000378966(transcript)|ensembl:ENST00000610924(transcript)|uniprotkb:Q8NA61-2(isoform-parent)	refseq:NP_012113.1|sgd:S000001415|mint:P40454|dip:DIP-5663N|ensemblfungi:YIL153W(gene)|ensemblfungi:YIL153W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006914"(autophagy)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008160"(protein tyrosine phosphatase activator activity)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0043618"(regulation of transcription from RNA polymerase II promoter in response to stress)|interpro:IPR004327(Phosphotyrosyl phosphatase activator, PTPA)|interpro:IPR037218|interpro:IPR043170|rcsb pdb:2IXO|rcsb pdb:2IXP	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:SogYcXGGMYRYzB9xKC5o0pEtsDs9606	rogid:It2q8WlpmvLEZ1fqpRF5Fypw9Q4559292	intact-crc:7FBDEB4DCCBF6005|rigid:bQV0FaOfr/y8MZEI89atVwxZAjI	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8NA61-2	uniprotkb:P32502	intact:EBI-11524851|ensembl:ENSP00000368249|ensembl:ENSP00000480148	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:q8na61-2(display_long)|uniprotkb:CBY2(gene name)|psi-mi:CBY2(display_short)|uniprotkb:SPERT(gene name synonym)|uniprotkb:Spermatid-associated protein(gene name synonym)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552724|imex:IM-24995-3752	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-741724(isoform-parent)|ensembl:ENSG00000174015(gene)|ensembl:ENST00000378966(transcript)|ensembl:ENST00000610924(transcript)|uniprotkb:Q8NA61-2(isoform-parent)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731	-	-	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:SogYcXGGMYRYzB9xKC5o0pEtsDs9606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:9789B3032590936A|rigid:1B4D21kYGCv/Xe0aARbP71v8ZGY	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P36019	uniprotkb:Q8NEU8	intact:EBI-29415|uniprotkb:Q45TZ5|uniprotkb:D6W187|ensemblfungi:YNL093W	intact:EBI-741261|ensembl:ENSP00000258530|uniprotkb:Q8N4R7|uniprotkb:Q9NVL2|uniprotkb:B7Z411|uniprotkb:B7Z4B0|uniprotkb:F5GZG0|uniprotkb:F8W1P5	psi-mi:ypt53_yeast(display_long)|uniprotkb:YPT53(gene name)|psi-mi:YPT53(display_short)|uniprotkb:N2223(orf name)|uniprotkb:YNL093W(locus name)	psi-mi:dp13b_human(display_long)|uniprotkb:Adapter protein containing PH domain, PTB domain and leucine zipper motif 2(gene name synonym)|uniprotkb:APPL2(gene name)|psi-mi:APPL2(display_short)|uniprotkb:DIP13B(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552760|imex:IM-24995-3761	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005037|refseq:NP_014306.3|dip:DIP-2025N|ensemblfungi:YNL093W(gene)|ensemblfungi:YNL093W_mRNA(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0006897"(endocytosis)|go:"GO:0012505"(endomembrane system)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417	go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0002024"(diet induced thermogenesis)|go:"GO:0005634"(nucleus)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0009631"(cold acclimation)|go:"GO:0010008"(endosome membrane)|go:"GO:0010762"(regulation of fibroblast migration)|go:"GO:0016020"(membrane)|go:"GO:0023052"(signaling)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032009"(early phagosome)|go:"GO:0032587"(ruffle membrane)|go:"GO:0033211"(adiponectin-activated signaling pathway)|go:"GO:0034143"(regulation of toll-like receptor 4 signaling pathway)|go:"GO:0035091"(phosphatidylinositol binding)|ensembl:ENSG00000136044(gene)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0036186"(early phagosome membrane)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|ensembl:ENST00000258530(transcript)|go:"GO:0044354"(macropinosome)|go:"GO:0001726"(ruffle)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000178"(negative regulation of neural precursor cell proliferation)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR027267|mint:Q8NEU8|rcsb pdb:4H8S|rcsb pdb:5C5B|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0046322"(negative regulation of fatty acid oxidation)|go:"GO:0046325"(negative regulation of glucose import)|go:"GO:0050768"(negative regulation of neurogenesis)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060100"(positive regulation of phagocytosis, engulfment)|go:"GO:0070062"(extracellular exosome)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1900016"(negative regulation of cytokine production involved in inflammatory response)|go:"GO:1900077"(negative regulation of cellular response to insulin stimulus)|go:"GO:1905303"(positive regulation of macropinocytosis)|go:"GO:1905451"(positive regulation of Fc-gamma receptor signaling pathway involved in phagocytosis)|refseq:NP_060641.2|refseq:XP_016875042.1|refseq:XP_016875041.1|refseq:NP_001238833.1|refseq:NP_001238834.1	-	crc64:ABA1D926D1EE9F68	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:2IDdF9ESvaxekyjmAzuRL9vMYJ8559292	rogid:8T+Y5phqYZ2On/CsfVVsOChSJNM9606	intact-crc:13948F1CB4FD0310|rigid:Vsh+AYUv89QAliyy3oxOk5Jo9I0	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8NEU8	uniprotkb:P36018	intact:EBI-741261|ensembl:ENSP00000258530|uniprotkb:Q8N4R7|uniprotkb:Q9NVL2|uniprotkb:B7Z411|uniprotkb:B7Z4B0|uniprotkb:F5GZG0|uniprotkb:F8W1P5	intact:EBI-29407|uniprotkb:D6VX79|ensemblfungi:YKR014C	psi-mi:dp13b_human(display_long)|uniprotkb:Adapter protein containing PH domain, PTB domain and leucine zipper motif 2(gene name synonym)|uniprotkb:APPL2(gene name)|psi-mi:APPL2(display_short)|uniprotkb:DIP13B(gene name synonym)	psi-mi:ypt52_yeast(display_long)|uniprotkb:YPT52(gene name)|psi-mi:YPT52(display_short)|uniprotkb:YK112(orf name)|uniprotkb:YKR014C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552756|imex:IM-24995-3760	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0002024"(diet induced thermogenesis)|go:"GO:0005634"(nucleus)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0009631"(cold acclimation)|go:"GO:0010008"(endosome membrane)|go:"GO:0010762"(regulation of fibroblast migration)|go:"GO:0016020"(membrane)|go:"GO:0023052"(signaling)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032009"(early phagosome)|go:"GO:0032587"(ruffle membrane)|go:"GO:0033211"(adiponectin-activated signaling pathway)|go:"GO:0034143"(regulation of toll-like receptor 4 signaling pathway)|go:"GO:0035091"(phosphatidylinositol binding)|ensembl:ENSG00000136044(gene)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0036186"(early phagosome membrane)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|ensembl:ENST00000258530(transcript)|go:"GO:0044354"(macropinosome)|go:"GO:0001726"(ruffle)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000178"(negative regulation of neural precursor cell proliferation)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR027267|mint:Q8NEU8|rcsb pdb:4H8S|rcsb pdb:5C5B|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0046322"(negative regulation of fatty acid oxidation)|go:"GO:0046325"(negative regulation of glucose import)|go:"GO:0050768"(negative regulation of neurogenesis)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060100"(positive regulation of phagocytosis, engulfment)|go:"GO:0070062"(extracellular exosome)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1900016"(negative regulation of cytokine production involved in inflammatory response)|go:"GO:1900077"(negative regulation of cellular response to insulin stimulus)|go:"GO:1905303"(positive regulation of macropinocytosis)|go:"GO:1905451"(positive regulation of Fc-gamma receptor signaling pathway involved in phagocytosis)|refseq:NP_060641.2|refseq:XP_016875042.1|refseq:XP_016875041.1|refseq:NP_001238833.1|refseq:NP_001238834.1	refseq:NP_012939.1|sgd:S000001722|dip:DIP-2121N|mint:P36018|ensemblfungi:YKR014C(gene)|ensemblfungi:YKR014C_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0006897"(endocytosis)|go:"GO:0012505"(endomembrane system)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0036258"(multivesicular body assembly)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|reactome:R-SCE-6798695|reactome:R-SCE-8856828|reactome:R-SCE-8873719|reactome:R-SCE-8876198|reactome:R-SCE-983231	-	-	crc64:34AB2FFE38697261	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:8T+Y5phqYZ2On/CsfVVsOChSJNM9606	rogid:KZ9/F9Ilto2oDHiPHffIM2gcVnY559292	intact-crc:21D06F1529963E5D|rigid:lHzj+ZFvH2+kCKWOePtCz1O1SO8	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P38340	uniprotkb:Q8NDC0	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-741424|uniprotkb:Q96BG5|ensembl:ENSP00000378851|ensembl:ENSP00000481882|uniprotkb:B2RDD8	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:missl_human(display_long)|uniprotkb:C14orf32(gene name synonym)|uniprotkb:Mitogen-activated protein kinase 1-interacting protein 1-like(gene name synonym)|uniprotkb:MAPK1IP1L(gene name)|psi-mi:MAPK1IP1L(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552740|imex:IM-24995-3756	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F	refseq:NP_653179.1|ensembl:ENSG00000168175(gene)|ensembl:ENST00000395468(transcript)|ensembl:ENST00000622254(transcript)|interpro:IPR031653	-	crc64:66699F37B0013088	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:CX220vB2TjggPEso5CHNUVzl79g9606	intact-crc:12D46A0F75168E06|rigid:WWegKoQBJiuvFiywqiCXJStd3AI	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8NEC5	uniprotkb:Q07986	intact:EBI-744545|uniprotkb:Q96P76|ensembl:ENSP00000309052	intact:EBI-37985|uniprotkb:D6VY39|ensemblfungi:YLR036C	psi-mi:ctsr1_human(display_long)|uniprotkb:CATSPER1(gene name)|psi-mi:CATSPER1(display_short)	psi-mi:yl036_yeast(display_long)|uniprotkb:YLR036C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552748|imex:IM-24995-3758	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_444282.3|ensembl:ENSG00000175294(gene)|ensembl:ENST00000312106(transcript)|go:"GO:0005227"(calcium activated cation channel activity)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007283"(spermatogenesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0031514"(motile cilium)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0036128"(CatSper complex)|go:"GO:0060296"(regulation of cilium beat frequency involved in ciliary motility)|interpro:IPR005821(Ion transport)|interpro:IPR027359|interpro:IPR028746|reactome:R-HSA-1300642	sgd:S000004026|refseq:NP_013137.1|dip:DIP-2127N|ensemblfungi:YLR036C(gene)|ensemblfungi:YLR036C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0016021"(integral component of membrane)|interpro:IPR031427	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:hY8kq7xGiDrD6FydKByugAo0t+U9606	rogid:GGcRlz7wYc6R9SI/NTywlmxOu8Q559292	intact-crc:0181AEDB974A8FA6|rigid:J0wMoMK8ttPT5GRI+vP3FHWpcTs	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8NDC0	uniprotkb:P53829	intact:EBI-741424|uniprotkb:Q96BG5|ensembl:ENSP00000378851|ensembl:ENSP00000481882|uniprotkb:B2RDD8	intact:EBI-28306|uniprotkb:D6W0Q5|ensemblfungi:YNL288W	psi-mi:missl_human(display_long)|uniprotkb:C14orf32(gene name synonym)|uniprotkb:Mitogen-activated protein kinase 1-interacting protein 1-like(gene name synonym)|uniprotkb:MAPK1IP1L(gene name)|psi-mi:MAPK1IP1L(display_short)	psi-mi:caf40_yeast(display_long)|uniprotkb:YNL288W(locus name)|uniprotkb:N0540(orf name)|uniprotkb:40 kDa CCR4-associated factor(gene name synonym)|uniprotkb:CAF40(gene name)|psi-mi:CAF40(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552744|imex:IM-24995-3757	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_653179.1|ensembl:ENSG00000168175(gene)|ensembl:ENST00000395468(transcript)|ensembl:ENST00000622254(transcript)|interpro:IPR031653	refseq:NP_014111.1|sgd:S000005232|dip:DIP-1995N|mint:P53829|ensemblfungi:YNL288W(gene)|ensemblfungi:YNL288W_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR007216(Cell differentiation, Rcd1-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:4CV5	-	-	crc64:F3DBABE6AD3C7F3C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:CX220vB2TjggPEso5CHNUVzl79g9606	rogid:etuSSgFGQOcgxPDexEXUqQg6H5s559292	intact-crc:E9E1851F647E0C42|rigid:omG8K9P74/OnVxCpgI4sniKFvzE	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8NEH6	intact:EBI-11522371	intact:EBI-743811|uniprotkb:Q8IYT6|uniprotkb:Q9NUP4|ensembl:ENSP00000260453	-	psi-mi:mns1_human(display_long)|uniprotkb:MNS1(gene name)|psi-mi:MNS1(display_short)	psi-mi:yjr003c(display_short)|psi-mi:EBI-11522371(display_long)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552752|imex:IM-24995-3759	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060835.1|ensembl:ENSG00000138587(gene)|ensembl:ENST00000260453(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005882"(intermediate filament)|go:"GO:0005930"(axoneme)|go:"GO:0007288"(sperm axoneme assembly)|go:"GO:0031514"(motile cilium)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042802"(identical protein binding)|go:"GO:0044782"(cilium organization)|go:"GO:0045724"(positive regulation of cilium assembly)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070986"(left/right axis specification)|interpro:IPR026504|interpro:IPR043597|mint:Q8NEH6	-	-	-	no-uniprot-update:	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:MRimzaWPUjIEXfbT3YufZtjt7Fk9606	rogid:dYGrrP3JnrXO2rj4v/nTT64la6A4932	intact-crc:CD042A58FAFC3F08|rigid:+zu8ArXu8e08GzieRA9lcwUAg1U	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8NHQ1	uniprotkb:P32502	intact:EBI-739624|ensembl:ENSP00000264982|ensembl:ENSP00000419231|uniprotkb:Q96B31|uniprotkb:Q9H2C3|uniprotkb:Q9H2Z1|uniprotkb:Q9H940|uniprotkb:D3DNE9|uniprotkb:B7Z5I8|uniprotkb:B7Z7E8|uniprotkb:F5GZX8	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:cep70_human(display_long)|uniprotkb:CEP70(gene name)|psi-mi:CEP70(display_short)|uniprotkb:BITE(gene name synonym)|uniprotkb:p10-binding protein(gene name synonym)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552788|imex:IM-24995-3768	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114107(gene)|ensembl:ENST00000264982(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|interpro:IPR019734|interpro:IPR037692|mint:Q8NHQ1|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|ensembl:ENST00000484888(transcript)|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_077817.2|refseq:XP_016862764.1|refseq:NP_001275893.1|refseq:NP_001275894.1|refseq:NP_001275895.1|refseq:NP_001275896.1|refseq:NP_001307527.1|refseq:NP_001307529.1	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731	-	-	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:S4yveQWcvdVtAUX65gqrJ5Dv0Mc9606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:987EFAC7F1F05BFC|rigid:wsx4pXsjZLscupso/4I0ctieg94	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P38340	uniprotkb:Q8NHQ1	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-739624|ensembl:ENSP00000264982|ensembl:ENSP00000419231|uniprotkb:Q96B31|uniprotkb:Q9H2C3|uniprotkb:Q9H2Z1|uniprotkb:Q9H940|uniprotkb:D3DNE9|uniprotkb:B7Z5I8|uniprotkb:B7Z7E8|uniprotkb:F5GZX8	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:cep70_human(display_long)|uniprotkb:CEP70(gene name)|psi-mi:CEP70(display_short)|uniprotkb:BITE(gene name synonym)|uniprotkb:p10-binding protein(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552784|imex:IM-24995-3767	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F	ensembl:ENSG00000114107(gene)|ensembl:ENST00000264982(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|interpro:IPR019734|interpro:IPR037692|mint:Q8NHQ1|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|ensembl:ENST00000484888(transcript)|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_077817.2|refseq:XP_016862764.1|refseq:NP_001275893.1|refseq:NP_001275894.1|refseq:NP_001275895.1|refseq:NP_001275896.1|refseq:NP_001307527.1|refseq:NP_001307529.1	-	crc64:66699F37B0013088	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:S4yveQWcvdVtAUX65gqrJ5Dv0Mc9606	intact-crc:D0F2CA0B6051973A|rigid:tp1An3X6liuUeZd/ZN9x5Ms1p3M	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8NHQ1	uniprotkb:P40454	intact:EBI-739624|ensembl:ENSP00000264982|ensembl:ENSP00000419231|uniprotkb:Q96B31|uniprotkb:Q9H2C3|uniprotkb:Q9H2Z1|uniprotkb:Q9H940|uniprotkb:D3DNE9|uniprotkb:B7Z5I8|uniprotkb:B7Z7E8|uniprotkb:F5GZX8	intact:EBI-25278|uniprotkb:D6VVD4|ensemblfungi:YIL153W	psi-mi:cep70_human(display_long)|uniprotkb:CEP70(gene name)|psi-mi:CEP70(display_short)|uniprotkb:BITE(gene name synonym)|uniprotkb:p10-binding protein(gene name synonym)	psi-mi:ptpa1_yeast(display_long)|uniprotkb:YIL153W(locus name)|uniprotkb:RRD1(gene name)|psi-mi:RRD1(display_short)|uniprotkb:NCS1(gene name synonym)|uniprotkb:YPA1(gene name synonym)|uniprotkb:Peptidyl-prolyl cis-trans isomerase PTPA-1(gene name synonym)|uniprotkb:Phosphotyrosyl phosphatase activator 1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552780|imex:IM-24995-3766	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114107(gene)|ensembl:ENST00000264982(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|interpro:IPR019734|interpro:IPR037692|mint:Q8NHQ1|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|ensembl:ENST00000484888(transcript)|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_077817.2|refseq:XP_016862764.1|refseq:NP_001275893.1|refseq:NP_001275894.1|refseq:NP_001275895.1|refseq:NP_001275896.1|refseq:NP_001307527.1|refseq:NP_001307529.1	refseq:NP_012113.1|sgd:S000001415|mint:P40454|dip:DIP-5663N|ensemblfungi:YIL153W(gene)|ensemblfungi:YIL153W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006914"(autophagy)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008160"(protein tyrosine phosphatase activator activity)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0043618"(regulation of transcription from RNA polymerase II promoter in response to stress)|interpro:IPR004327(Phosphotyrosyl phosphatase activator, PTPA)|interpro:IPR037218|interpro:IPR043170|rcsb pdb:2IXO|rcsb pdb:2IXP	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:S4yveQWcvdVtAUX65gqrJ5Dv0Mc9606	rogid:It2q8WlpmvLEZ1fqpRF5Fypw9Q4559292	intact-crc:53BBD70557C4AB66|rigid:xt0sTaF6qMCpURJuIBUzQiFieOM	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8NEU8	uniprotkb:P40303	intact:EBI-741261|ensembl:ENSP00000258530|uniprotkb:Q8N4R7|uniprotkb:Q9NVL2|uniprotkb:B7Z411|uniprotkb:B7Z4B0|uniprotkb:F5GZG0|uniprotkb:F8W1P5	intact:EBI-13980|ensemblfungi:YOL038W|uniprotkb:D6W229	psi-mi:dp13b_human(display_long)|uniprotkb:Adapter protein containing PH domain, PTB domain and leucine zipper motif 2(gene name synonym)|uniprotkb:APPL2(gene name)|psi-mi:APPL2(display_short)|uniprotkb:DIP13B(gene name synonym)	psi-mi:psa4_yeast(display_long)|uniprotkb:PRE6(gene name)|psi-mi:PRE6(display_short)|uniprotkb:YOL038W(locus name)|uniprotkb:Proteasome component PRE6(gene name synonym)|uniprotkb:Macropain subunit PRE6(gene name synonym)|uniprotkb:Proteinase YSCE subunit PRE6(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit PRE6(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552764|imex:IM-24995-3762	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0002024"(diet induced thermogenesis)|go:"GO:0005634"(nucleus)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0009631"(cold acclimation)|go:"GO:0010008"(endosome membrane)|go:"GO:0010762"(regulation of fibroblast migration)|go:"GO:0016020"(membrane)|go:"GO:0023052"(signaling)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032009"(early phagosome)|go:"GO:0032587"(ruffle membrane)|go:"GO:0033211"(adiponectin-activated signaling pathway)|go:"GO:0034143"(regulation of toll-like receptor 4 signaling pathway)|go:"GO:0035091"(phosphatidylinositol binding)|ensembl:ENSG00000136044(gene)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0036186"(early phagosome membrane)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|ensembl:ENST00000258530(transcript)|go:"GO:0044354"(macropinosome)|go:"GO:0001726"(ruffle)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000178"(negative regulation of neural precursor cell proliferation)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR027267|mint:Q8NEU8|rcsb pdb:4H8S|rcsb pdb:5C5B|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0046322"(negative regulation of fatty acid oxidation)|go:"GO:0046325"(negative regulation of glucose import)|go:"GO:0050768"(negative regulation of neurogenesis)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060100"(positive regulation of phagocytosis, engulfment)|go:"GO:0070062"(extracellular exosome)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1900016"(negative regulation of cytokine production involved in inflammatory response)|go:"GO:1900077"(negative regulation of cellular response to insulin stimulus)|go:"GO:1905303"(positive regulation of macropinocytosis)|go:"GO:1905451"(positive regulation of Fc-gamma receptor signaling pathway involved in phagocytosis)|refseq:NP_060641.2|refseq:XP_016875042.1|refseq:XP_016875041.1|refseq:NP_001238833.1|refseq:NP_001238834.1	ensemblfungi:YOL038W(gene)|ensemblfungi:YOL038W_mRNA(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0042175"(nuclear outer membrane-endoplasmic reticulum membrane network)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023332|interpro:IPR029055|rcsb pdb:1FNT|rcsb pdb:1G0U|rcsb pdb:1G65|rcsb pdb:1JD2|rcsb pdb:1RYP|rcsb pdb:1Z7Q|rcsb pdb:2F16|rcsb pdb:2FAK|rcsb pdb:2GPL|rcsb pdb:2ZCY|rcsb pdb:3BDM|rcsb pdb:3D29|rcsb pdb:3DY3|rcsb pdb:3DY4|rcsb pdb:4QZ1|rcsb pdb:4QZ2|rcsb pdb:4QZ3|rcsb pdb:4QZ4|rcsb pdb:4QZ5|rcsb pdb:4QZ6|rcsb pdb:4QZ7|rcsb pdb:4QZW|rcsb pdb:4QZX|rcsb pdb:4QZZ|rcsb pdb:4R00|rcsb pdb:4R02|rcsb pdb:4R17|rcsb pdb:4R18|rcsb pdb:4RUR|rcsb pdb:4V7O|rcsb pdb:4X6Z|rcsb pdb:4Y69|rcsb pdb:4Y6A|rcsb pdb:4Y6V|rcsb pdb:4Y6Z|rcsb pdb:4Y70|rcsb pdb:4Y74|rcsb pdb:4Y75|rcsb pdb:4Y77|rcsb pdb:4Y78|rcsb pdb:4Y7W|rcsb pdb:4Y7X|rcsb pdb:4Y7Y|rcsb pdb:4Y80|rcsb pdb:4QZ0|rcsb pdb:4Y81|rcsb pdb:4Y82|rcsb pdb:4Y84|rcsb pdb:4Y8H|rcsb pdb:4Y8I|rcsb pdb:4Y8J|rcsb pdb:4Y8K|rcsb pdb:4Y8L|rcsb pdb:4Y8M|rcsb pdb:4Y8N|rcsb pdb:4Y8O|rcsb pdb:4Y8P|rcsb pdb:4Y8Q|rcsb pdb:4Y8R|rcsb pdb:4Y8S|rcsb pdb:4Y8T|rcsb pdb:4Y8U|rcsb pdb:4Y9Y|rcsb pdb:4Y9Z|rcsb pdb:4YA0|rcsb pdb:4YA1|rcsb pdb:4YA2|rcsb pdb:4YA3|rcsb pdb:4Y8G|rcsb pdb:4YA4|rcsb pdb:4YA5|rcsb pdb:4YA7|rcsb pdb:4YA9|rcsb pdb:4Z1L|rcsb pdb:5A5B|rcsb pdb:5AHJ|rcsb pdb:5BOU|rcsb pdb:5BXN|rcsb pdb:5CGF|rcsb pdb:5CGG|rcsb pdb:5CGH|rcsb pdb:5CGI|rcsb pdb:5CZ4|rcsb pdb:5CZ5|rcsb pdb:5CZ6|rcsb pdb:5CZ7|rcsb pdb:5CZ8|rcsb pdb:5CZ9|rcsb pdb:5CZA|rcsb pdb:5D0S|rcsb pdb:5D0T|rcsb pdb:5D0V|rcsb pdb:5D0W|rcsb pdb:5D0X|rcsb pdb:5BXL|rcsb pdb:5D0Z|rcsb pdb:5DKI|rcsb pdb:5DKJ|rcsb pdb:5FG9|rcsb pdb:5FGA|rcsb pdb:5FGD|rcsb pdb:5FGE|rcsb pdb:5FGF|rcsb pdb:5FGG|rcsb pdb:5FGH|rcsb pdb:5FG7|rcsb pdb:5FGI|rcsb pdb:5FHS|rcsb pdb:5JHR|rcsb pdb:5JHS|rcsb pdb:5L52|rcsb pdb:5L54|rcsb pdb:5L55|rcsb pdb:5L5A|rcsb pdb:5L5B|rcsb pdb:5L5D|rcsb pdb:5L5E|rcsb pdb:5L5F|rcsb pdb:5L5H|rcsb pdb:5L5I|rcsb pdb:5L5J|rcsb pdb:5L5O|rcsb pdb:5L5P|rcsb pdb:5L5Q|rcsb pdb:5L5R|rcsb pdb:5L5S|rcsb pdb:5L5T|rcsb pdb:5L5U|rcsb pdb:5L5V|rcsb pdb:5L5W|rcsb pdb:5L5X|rcsb pdb:5L5Y|rcsb pdb:5L5Z|rcsb pdb:5L60|rcsb pdb:5L61|rcsb pdb:5L62|rcsb pdb:5L63|rcsb pdb:5L64|rcsb pdb:5L65|rcsb pdb:5L66|rcsb pdb:5L67|rcsb pdb:5L68|rcsb pdb:5L69|rcsb pdb:5L6A|rcsb pdb:5L6B|rcsb pdb:5LAI|rcsb pdb:5LAJ|rcsb pdb:5LTT|rcsb pdb:5M2B|rcsb pdb:5MP9|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5NIF|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:5L6C|rcsb pdb:6FVW|rcsb pdb:6FVY|rcsb pdb:6G7F|rcsb pdb:6G8M|rcsb pdb:6G8N|rcsb pdb:6GOP|rcsb pdb:6H39|rcsb pdb:6HTB|rcsb pdb:6HTC|rcsb pdb:6HTD|rcsb pdb:6HTP|rcsb pdb:6HTR|rcsb pdb:6HUB|rcsb pdb:6HUC|rcsb pdb:6HUQ|rcsb pdb:6FVX|rcsb pdb:6HUU|rcsb pdb:6HUV|rcsb pdb:6HV3|rcsb pdb:6HV4|rcsb pdb:6HV5|rcsb pdb:6HV7|rcsb pdb:6HVA|rcsb pdb:6HVR|rcsb pdb:6HVS|rcsb pdb:6HVT|rcsb pdb:6HVU|rcsb pdb:6HVV|rcsb pdb:6HVW|rcsb pdb:6HVX|rcsb pdb:6HVY|rcsb pdb:6HW0|rcsb pdb:6HW3|rcsb pdb:6HW4|rcsb pdb:6HW5|rcsb pdb:6HW6|rcsb pdb:6HW7|rcsb pdb:6HW8|rcsb pdb:6HW9|rcsb pdb:6HWA|rcsb pdb:6HWB|rcsb pdb:6HWC|rcsb pdb:6HWE|rcsb pdb:6HWF|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6HWD|rcsb pdb:6J2X|rcsb pdb:6J30|rcsb pdb:6ZOU|rcsb pdb:6ZP6|rcsb pdb:6ZP8|rcsb pdb:7LS5|rcsb pdb:7LS6|rcsb pdb:7LSX|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|rcsb pdb:3E47|rcsb pdb:3GPJ|rcsb pdb:3GPT|rcsb pdb:3GPW|rcsb pdb:3HYE|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:3MG0|rcsb pdb:3MG4|rcsb pdb:3MG6|rcsb pdb:3MG7|rcsb pdb:3MG8|rcsb pdb:3NZJ|rcsb pdb:3NZW|rcsb pdb:3NZX|rcsb pdb:3OEU|rcsb pdb:3OEV|rcsb pdb:3OKJ|rcsb pdb:3SDI|rcsb pdb:3SDK|rcsb pdb:3SHJ|rcsb pdb:3TDD|rcsb pdb:3UN4|rcsb pdb:3UN8|rcsb pdb:3WXR|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:4EU2|rcsb pdb:4FZC|rcsb pdb:4FZG|rcsb pdb:4G4S|rcsb pdb:4GK7|rcsb pdb:4HRC|rcsb pdb:4HRD|rcsb pdb:4INR|rcsb pdb:4INT|rcsb pdb:4INU|rcsb pdb:4J70|rcsb pdb:4JSQ|rcsb pdb:4JSU|rcsb pdb:4JT0|rcsb pdb:4LQI|rcsb pdb:4LTC|rcsb pdb:4NNN|rcsb pdb:4NNW|rcsb pdb:4NO1|rcsb pdb:4HNP|rcsb pdb:4NO6|rcsb pdb:4NO8|rcsb pdb:4NO9|rcsb pdb:4Q1S|rcsb pdb:4QBY|rcsb pdb:4QLQ|rcsb pdb:4QLS|rcsb pdb:4QLT|rcsb pdb:4QLU|rcsb pdb:4QLV|rcsb pdb:4QUX|rcsb pdb:4QUY|rcsb pdb:4QV1|rcsb pdb:4QV3|rcsb pdb:4QV4|rcsb pdb:4QV5|rcsb pdb:4QV6|rcsb pdb:4QV7|rcsb pdb:4QV8|rcsb pdb:4QV9|rcsb pdb:4QVL|rcsb pdb:4QVM|rcsb pdb:4QVN|rcsb pdb:4QVP|rcsb pdb:4QVQ|rcsb pdb:4QVV|rcsb pdb:4QVW|rcsb pdb:4QVY|rcsb pdb:4QW0|rcsb pdb:4QW1|rcsb pdb:4QW3|rcsb pdb:4QW4|rcsb pdb:4QW5|rcsb pdb:4QW6|rcsb pdb:4QW7|rcsb pdb:4QWF|rcsb pdb:4QWG|rcsb pdb:4QV0|rcsb pdb:4QWI|rcsb pdb:4QWJ|rcsb pdb:4QWK|rcsb pdb:4QWL|rcsb pdb:4QWR|rcsb pdb:4QWS|rcsb pdb:4QWU|rcsb pdb:4QWX|rcsb pdb:4QXJ|refseq:NP_014604.1|sgd:S000005398|mint:P40303|dip:DIP-4844N	-	-	crc64:73AEE63B836E618A	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:8T+Y5phqYZ2On/CsfVVsOChSJNM9606	rogid:G8IQr0G8FhiWc0DYUlh3vecHQsU559292	intact-crc:81BFE9270FAEB311|rigid:tKdwVIRRkDlkwHnZtCmlUdnHbM4	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P25372	uniprotkb:Q8NF99-2	intact:EBI-19616|uniprotkb:D6VR84|ensemblfungi:YCR083W	intact:EBI-11524467|ensembl:ENSP00000261333	psi-mi:trx3_yeast(display_long)|uniprotkb:TRX3(gene name)|psi-mi:TRX3(display_short)|uniprotkb:YCR83W(orf name)|uniprotkb:YCR083W(locus name)	psi-mi:q8nf99-2(display_long)|uniprotkb:ZNF47(gene name synonym)|uniprotkb:ZSCAN15(gene name synonym)|uniprotkb:Zinc finger and SCAN domain-containing protein 15(gene name synonym)|uniprotkb:Zinc finger protein 47(gene name synonym)|uniprotkb:ZNF397(gene name)|psi-mi:ZNF397(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552772|imex:IM-24995-3764	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR036249|refseq:NP_010006.1|sgd:S000000679|interpro:IPR017937|interpro:IPR013766(Thioredoxin domain)|rcsb pdb:2OE0|rcsb pdb:2OE1|rcsb pdb:2OE3|ensemblfungi:YCR083W(gene)|ensemblfungi:YCR083W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0015036"(disulfide oxidoreductase activity)|go:"GO:0034599"(cellular response to oxidative stress)|rcsb pdb:5YKW	intact:EBI-10213894(isoform-parent)|ensembl:ENSG00000186812(gene)|ensembl:ENST00000261333(transcript)|uniprotkb:Q8NF99-2(isoform-parent)	-	-	isoform-comment:No experimental confirmation available.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:g0xjGf9GvJRl8iv2qoT5tOs7jXI559292	rogid:CGdD3rsdZjS7lhobp1xohK8ewPg9606	intact-crc:0B1F9444944C02D6|rigid:b8nkJhl66djEkj5zPYbYu0c2h4g	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8NF64	uniprotkb:P38635	intact:EBI-745786|uniprotkb:O94790|uniprotkb:Q0VGB4|uniprotkb:Q659A8|uniprotkb:Q6JKL5|uniprotkb:Q8WTX8|uniprotkb:Q96Q01|uniprotkb:Q9BQH7|uniprotkb:A4D2K7|uniprotkb:D3DVL1|intact:EBI-28976701|ensembl:ENSP00000311778|ensembl:ENSP00000414723	intact:EBI-2045554|uniprotkb:D6VTQ5|ensemblfungi:YFR025C	psi-mi:zmiz2_human(display_long)|uniprotkb:PIAS-like protein Zimp7(gene name synonym)|uniprotkb:ZMIZ2(gene name)|psi-mi:ZMIZ2(display_short)|uniprotkb:KIAA1886(gene name synonym)|uniprotkb:HRIHFB2007(orf name)|uniprotkb:ZIMP7(gene name synonym)	psi-mi:his9_yeast(display_long)|uniprotkb:YFR025C(locus name)|uniprotkb:HIS2(gene name)|psi-mi:HIS2(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552768|imex:IM-24995-3763	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_113637.3|refseq:NP_777589.2|ensembl:ENST00000265346|ensembl:ENSP00000265346|ensembl:ENSP00000311778|ensembl:ENST00000413916|ensembl:ENSP00000409648|ensembl:ENSP00000414723|refseq:NP_001287888.1|ensembl:ENSG00000122515(gene)|ensembl:ENST00000309315(transcript)|ensembl:ENST00000441627(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048096"|interpro:IPR004181(Zinc finger, MIZ-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|refseq:XP_005249926.1|refseq:XP_005249929.1	refseq:NP_116681.1|sgd:S000001921|interpro:IPR010140(Histidinol phosphate phosphatase, HisJ)|interpro:IPR004013(PHP, C-terminal)|interpro:IPR016195(Polymerase and histidinol phosphatase-like)|mint:P38635|ensemblfungi:YFR025C(gene)|ensemblfungi:YFR025C_mRNA(transcript)|go:"GO:0000105"(histidine biosynthetic process)|go:"GO:0004401"(histidinol-phosphatase activity)|go:"GO:0005737"(cytoplasm)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:gkO57EyOLACt/8WYxFQbasiqRro9606	rogid:3gGqFDbJWtM4it1O4HJjk6KoTL4559292	intact-crc:CA3D222F7D58DE88|rigid:BOZGMKK7jJJWJv9E7l0s2M5uWlo	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8NFF5-2	uniprotkb:P32502	intact:EBI-11526128|ensembl:ENSP00000317296	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:q8nff5-2(display_long)|uniprotkb:FLAD1(gene name)|psi-mi:FLAD1(display_short)|uniprotkb:FAD pyrophosphorylase(gene name synonym)|uniprotkb:FMN adenylyltransferase(gene name synonym)|uniprotkb:Flavin adenine dinucleotide synthase(gene name synonym)|uniprotkb:PP591(orf name)|uniprotkb:FADS2(isoform synonym)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552776|imex:IM-24995-3765	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:Q8NFF5-2(isoform-parent)|intact:EBI-742815(isoform-parent)|ensembl:ENST00000315144(transcript)|ensembl:ENSG00000160688(gene)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731	-	-	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:BU/WYJYTvm8VgRPN+e8jjYiw5yU9606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:C6CFAAB133E87C75|rigid:LLyV3rv2PbU1E8qBienKt/ARbcE	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8NHQ1	uniprotkb:Q12460	intact:EBI-739624|ensembl:ENSP00000264982|ensembl:ENSP00000419231|uniprotkb:Q96B31|uniprotkb:Q9H2C3|uniprotkb:Q9H2Z1|uniprotkb:Q9H940|uniprotkb:D3DNE9|uniprotkb:B7Z5I8|uniprotkb:B7Z7E8|uniprotkb:F5GZX8	intact:EBI-17148|ensemblfungi:YLR197W|uniprotkb:D6VYK0	psi-mi:cep70_human(display_long)|uniprotkb:CEP70(gene name)|psi-mi:CEP70(display_short)|uniprotkb:BITE(gene name synonym)|uniprotkb:p10-binding protein(gene name synonym)	psi-mi:nop56_yeast(display_long)|uniprotkb:SIK1(gene name synonym)|uniprotkb:Ribosome biosynthesis protein SIK1(gene name synonym)|uniprotkb:YLR197W(locus name)|uniprotkb:L8167.9(orf name)|uniprotkb:NOP56(gene name)|psi-mi:NOP56(display_short)|uniprotkb:Suppressor of I kappa b protein 1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552808|imex:IM-24995-3773	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114107(gene)|ensembl:ENST00000264982(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|interpro:IPR019734|interpro:IPR037692|mint:Q8NHQ1|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|ensembl:ENST00000484888(transcript)|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_077817.2|refseq:XP_016862764.1|refseq:NP_001275893.1|refseq:NP_001275894.1|refseq:NP_001275895.1|refseq:NP_001275896.1|refseq:NP_001307527.1|refseq:NP_001307529.1	ensemblfungi:YLR197W(gene)|ensemblfungi:YLR197W_mRNA(transcript)|go:"GO:0000154"(rRNA modification)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|refseq:NP_013298.1|sgd:S000004187|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0030515"(snoRNA binding)|go:"GO:0030686"(90S preribosome)|go:"GO:0031428"(box C/D RNP complex)|go:"GO:0032040"(small-subunit processome)|interpro:IPR002687(Pre-mRNA processing ribonucleoprotein, binding region)|interpro:IPR012974(NOP5, N-terminal)|interpro:IPR012976(NOSIC)|interpro:IPR036070|interpro:IPR042239|rcsb pdb:5WLC|rcsb pdb:5WYJ|rcsb pdb:5WYK|rcsb pdb:6KE6|rcsb pdb:6LQP|rcsb pdb:6LQQ|rcsb pdb:6LQR|rcsb pdb:6LQS|rcsb pdb:6LQT|rcsb pdb:6LQU|rcsb pdb:6LQV|rcsb pdb:6ND4|rcsb pdb:6ZDT|rcsb pdb:6ZQA|rcsb pdb:6ZQB|rcsb pdb:6ZQC|rcsb pdb:6ZQD|rcsb pdb:6ZQE|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-6791226|dip:DIP-4405N|mint:Q12460	-	-	crc64:F8522A5870EF4842	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:S4yveQWcvdVtAUX65gqrJ5Dv0Mc9606	rogid:l3UAmoOUECH1uov6nv7MSwSv/3s559292	intact-crc:BF3BDE77957B0D11|rigid:RlecPvmCstDP0ZnBJvCs/F+2cLA	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P46682	uniprotkb:Q8NHQ1	intact:EBI-2213|uniprotkb:D6VV40|ensemblfungi:YGR261C	intact:EBI-739624|ensembl:ENSP00000264982|ensembl:ENSP00000419231|uniprotkb:Q96B31|uniprotkb:Q9H2C3|uniprotkb:Q9H2Z1|uniprotkb:Q9H940|uniprotkb:D3DNE9|uniprotkb:B7Z5I8|uniprotkb:B7Z7E8|uniprotkb:F5GZX8	psi-mi:ap3b_yeast(display_long)|uniprotkb:APL6(gene name)|psi-mi:APL6(display_short)|uniprotkb:YKS5(gene name synonym)|uniprotkb:YGR261C(locus name)|uniprotkb:G9331(orf name)|uniprotkb:Beta-3-adaptin(gene name synonym)|uniprotkb:Clathrin assembly protein complex 3 beta large chain(gene name synonym)|uniprotkb:Clathrin assembly protein large beta chain(gene name synonym)|uniprotkb:Adaptor-related protein complex 3 subunit beta(gene name synonym)	psi-mi:cep70_human(display_long)|uniprotkb:CEP70(gene name)|psi-mi:CEP70(display_short)|uniprotkb:BITE(gene name synonym)|uniprotkb:p10-binding protein(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552804|imex:IM-24995-3772	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003493|refseq:NP_011777.3|ensemblfungi:YGR261C(gene)|ensemblfungi:YGR261C_mRNA(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030123"(AP-3 adaptor complex)|go:"GO:0030665"(clathrin-coated vesicle membrane)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026739|interpro:IPR026740|dip:DIP-2684N|mint:P46682	ensembl:ENSG00000114107(gene)|ensembl:ENST00000264982(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|interpro:IPR019734|interpro:IPR037692|mint:Q8NHQ1|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|ensembl:ENST00000484888(transcript)|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_077817.2|refseq:XP_016862764.1|refseq:NP_001275893.1|refseq:NP_001275894.1|refseq:NP_001275895.1|refseq:NP_001275896.1|refseq:NP_001307527.1|refseq:NP_001307529.1	-	crc64:475DA3A4F6E68E97	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:J+pCwMtq9Jhj24BeTVg7XpCHmKE559292	rogid:S4yveQWcvdVtAUX65gqrJ5Dv0Mc9606	intact-crc:3FA7DEBFBDAF523F|rigid:M8Dkr3+t2NvMQ21DMTr7naSknDo	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P25372	uniprotkb:Q8NHQ1	intact:EBI-19616|uniprotkb:D6VR84|ensemblfungi:YCR083W	intact:EBI-739624|ensembl:ENSP00000264982|ensembl:ENSP00000419231|uniprotkb:Q96B31|uniprotkb:Q9H2C3|uniprotkb:Q9H2Z1|uniprotkb:Q9H940|uniprotkb:D3DNE9|uniprotkb:B7Z5I8|uniprotkb:B7Z7E8|uniprotkb:F5GZX8	psi-mi:trx3_yeast(display_long)|uniprotkb:TRX3(gene name)|psi-mi:TRX3(display_short)|uniprotkb:YCR83W(orf name)|uniprotkb:YCR083W(locus name)	psi-mi:cep70_human(display_long)|uniprotkb:CEP70(gene name)|psi-mi:CEP70(display_short)|uniprotkb:BITE(gene name synonym)|uniprotkb:p10-binding protein(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552792|imex:IM-24995-3769	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR036249|refseq:NP_010006.1|sgd:S000000679|interpro:IPR017937|interpro:IPR013766(Thioredoxin domain)|rcsb pdb:2OE0|rcsb pdb:2OE1|rcsb pdb:2OE3|ensemblfungi:YCR083W(gene)|ensemblfungi:YCR083W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0015036"(disulfide oxidoreductase activity)|go:"GO:0034599"(cellular response to oxidative stress)|rcsb pdb:5YKW	ensembl:ENSG00000114107(gene)|ensembl:ENST00000264982(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|interpro:IPR019734|interpro:IPR037692|mint:Q8NHQ1|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|ensembl:ENST00000484888(transcript)|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_077817.2|refseq:XP_016862764.1|refseq:NP_001275893.1|refseq:NP_001275894.1|refseq:NP_001275895.1|refseq:NP_001275896.1|refseq:NP_001307527.1|refseq:NP_001307529.1	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:g0xjGf9GvJRl8iv2qoT5tOs7jXI559292	rogid:S4yveQWcvdVtAUX65gqrJ5Dv0Mc9606	intact-crc:939F05CC0EFCBC1D|rigid:USumgpr/MOfPlWxaf3nEjvTt9Sw	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8NHQ1	uniprotkb:P39724	intact:EBI-739624|ensembl:ENSP00000264982|ensembl:ENSP00000419231|uniprotkb:Q96B31|uniprotkb:Q9H2C3|uniprotkb:Q9H2Z1|uniprotkb:Q9H940|uniprotkb:D3DNE9|uniprotkb:B7Z5I8|uniprotkb:B7Z7E8|uniprotkb:F5GZX8	intact:EBI-2343154|uniprotkb:D6VPH0|ensemblfungi:YAL046C	psi-mi:cep70_human(display_long)|uniprotkb:CEP70(gene name)|psi-mi:CEP70(display_short)|uniprotkb:BITE(gene name synonym)|uniprotkb:p10-binding protein(gene name synonym)	psi-mi:bol3_yeast(display_long)|uniprotkb:BOL3(gene name)|psi-mi:BOL3(display_short)|uniprotkb:AIM1(gene name synonym)|uniprotkb:Altered inheritance of mitochondria protein 1(gene name synonym)|uniprotkb:YAL046C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552796|imex:IM-24995-3770	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114107(gene)|ensembl:ENST00000264982(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|interpro:IPR019734|interpro:IPR037692|mint:Q8NHQ1|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|ensembl:ENST00000484888(transcript)|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_077817.2|refseq:XP_016862764.1|refseq:NP_001275893.1|refseq:NP_001275894.1|refseq:NP_001275895.1|refseq:NP_001275896.1|refseq:NP_001307527.1|refseq:NP_001307529.1	refseq:NP_009353.1|sgd:S000000044|interpro:IPR002634(BolA-like protein)|interpro:IPR036065|mint:P39724|ensemblfungi:YAL046C(gene)|ensemblfungi:YAL046C_mRNA(transcript)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0106035"(protein maturation by [4Fe-4S] cluster transfer)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:S4yveQWcvdVtAUX65gqrJ5Dv0Mc9606	rogid:MLrW6Iu4YKXf87O1cyx5bY03VdE559292	intact-crc:3522F13BFBD72AAA|rigid:8wdt3l1cquQehSaPTrETtvhqtDw	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q06132	uniprotkb:Q8NHQ1	intact:EBI-34377|uniprotkb:D6VYX6|ensemblfungi:YLR336C	intact:EBI-739624|ensembl:ENSP00000264982|ensembl:ENSP00000419231|uniprotkb:Q96B31|uniprotkb:Q9H2C3|uniprotkb:Q9H2Z1|uniprotkb:Q9H940|uniprotkb:D3DNE9|uniprotkb:B7Z5I8|uniprotkb:B7Z7E8|uniprotkb:F5GZX8	psi-mi:sgd1_yeast(display_long)|uniprotkb:SGD1(gene name)|psi-mi:SGD1(display_short)|uniprotkb:YLR336C(locus name)	psi-mi:cep70_human(display_long)|uniprotkb:CEP70(gene name)|psi-mi:CEP70(display_short)|uniprotkb:BITE(gene name synonym)|uniprotkb:p10-binding protein(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552800|imex:IM-24995-3771	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013440.1|sgd:S000004328|mint:Q06132|dip:DIP-6333N|ensemblfungi:YLR336C(gene)|ensemblfungi:YLR336C_mRNA(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0006972"(hyperosmotic response)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0097078"(FAL1-SGD1 complex)|interpro:IPR003890(MIF4G-like, type 3)|interpro:IPR003891(Initiation factor eIF-4 gamma, MA3)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR016024(Armadillo-type fold)	ensembl:ENSG00000114107(gene)|ensembl:ENST00000264982(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|interpro:IPR019734|interpro:IPR037692|mint:Q8NHQ1|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|ensembl:ENST00000484888(transcript)|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_077817.2|refseq:XP_016862764.1|refseq:NP_001275893.1|refseq:NP_001275894.1|refseq:NP_001275895.1|refseq:NP_001275896.1|refseq:NP_001307527.1|refseq:NP_001307529.1	-	crc64:8EEFDB8258407FF3	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:FxZCxGejbcvEs/J2h1HEaWeVZLQ559292	rogid:S4yveQWcvdVtAUX65gqrJ5Dv0Mc9606	intact-crc:0A7568AC74C99FC7|rigid:PjjAmKyVVhJH+yc25AGY624IdxM	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8NHQ1	uniprotkb:P32902	intact:EBI-739624|ensembl:ENSP00000264982|ensembl:ENSP00000419231|uniprotkb:Q96B31|uniprotkb:Q9H2C3|uniprotkb:Q9H2Z1|uniprotkb:Q9H940|uniprotkb:D3DNE9|uniprotkb:B7Z5I8|uniprotkb:B7Z7E8|uniprotkb:F5GZX8	intact:EBI-16248|ensemblfungi:YHL004W|uniprotkb:D3DKR0	psi-mi:cep70_human(display_long)|uniprotkb:CEP70(gene name)|psi-mi:CEP70(display_short)|uniprotkb:BITE(gene name synonym)|uniprotkb:p10-binding protein(gene name synonym)	psi-mi:rt04_yeast(display_long)|uniprotkb:MRP4(gene name)|psi-mi:MRP4(display_short)|uniprotkb:MRP4A(gene name synonym)|uniprotkb:Mitochondrial small ribosomal subunit protein uS2m(gene name synonym)|uniprotkb:YHL004W(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552832|imex:IM-24995-3779	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114107(gene)|ensembl:ENST00000264982(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|interpro:IPR019734|interpro:IPR037692|mint:Q8NHQ1|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|ensembl:ENST00000484888(transcript)|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_077817.2|refseq:XP_016862764.1|refseq:NP_001275893.1|refseq:NP_001275894.1|refseq:NP_001275895.1|refseq:NP_001275896.1|refseq:NP_001307527.1|refseq:NP_001307529.1	ensemblfungi:YHL004W(gene)|ensemblfungi:YHL004W_mRNA(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR001865(Ribosomal protein S2)|interpro:IPR005706(Ribosomal protein S2, bacterial-type)|interpro:IPR018130|interpro:IPR023591|rcsb pdb:5MRC|rcsb pdb:5MRE|rcsb pdb:5MRF|refseq:NP_011859.1|sgd:S000000996|dip:DIP-5035N|mint:P32902	-	-	crc64:81A1CB33134BC559	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:S4yveQWcvdVtAUX65gqrJ5Dv0Mc9606	rogid:BlL3W6HUN+uAKF/AxwlV1zT5YZQ559292	intact-crc:9AB34A4F264148DE|rigid:J2sM+DbG+y7tjVL8ykgESazQzJQ	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8NHQ1	uniprotkb:P53286	intact:EBI-739624|ensembl:ENSP00000264982|ensembl:ENSP00000419231|uniprotkb:Q96B31|uniprotkb:Q9H2C3|uniprotkb:Q9H2Z1|uniprotkb:Q9H940|uniprotkb:D3DNE9|uniprotkb:B7Z5I8|uniprotkb:B7Z7E8|uniprotkb:F5GZX8	intact:EBI-3796|uniprotkb:D6VUS2|ensemblfungi:YGR142W	psi-mi:cep70_human(display_long)|uniprotkb:CEP70(gene name)|psi-mi:CEP70(display_short)|uniprotkb:BITE(gene name synonym)|uniprotkb:p10-binding protein(gene name synonym)	psi-mi:btn2_yeast(display_long)|uniprotkb:YGR142W(locus name)|uniprotkb:BTN2(gene name)|psi-mi:BTN2(display_short)|uniprotkb:Batten disease protein 2(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552828|imex:IM-24995-3778	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114107(gene)|ensembl:ENST00000264982(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|interpro:IPR019734|interpro:IPR037692|mint:Q8NHQ1|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|ensembl:ENST00000484888(transcript)|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_077817.2|refseq:XP_016862764.1|refseq:NP_001275893.1|refseq:NP_001275894.1|refseq:NP_001275895.1|refseq:NP_001275896.1|refseq:NP_001307527.1|refseq:NP_001307529.1	sgd:S000003374|refseq:NP_011658.3|dip:DIP-5534N|mint:P53286|ensemblfungi:YGR142W(gene)|ensemblfungi:YGR142W_mRNA(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005634"(nucleus)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006865"(amino acid transport)|go:"GO:0006885"(regulation of pH)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051087"(chaperone binding)|go:"GO:0140311"(protein sequestering activity)	-	-	crc64:E7AE1EB1E3612F3E	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:S4yveQWcvdVtAUX65gqrJ5Dv0Mc9606	rogid:Cu27xkwGMNyS4zLvUaG1UeH2mE0559292	intact-crc:19321932CF3A98C9|rigid:kjA+AlYSmx6ikhMZAUDlty+Ng0g	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P47130	uniprotkb:Q8NHQ1	intact:EBI-763|uniprotkb:D6VWQ3|ensemblfungi:YJR084W	intact:EBI-739624|ensembl:ENSP00000264982|ensembl:ENSP00000419231|uniprotkb:Q96B31|uniprotkb:Q9H2C3|uniprotkb:Q9H2Z1|uniprotkb:Q9H940|uniprotkb:D3DNE9|uniprotkb:B7Z5I8|uniprotkb:B7Z7E8|uniprotkb:F5GZX8	psi-mi:csn12_yeast(display_long)|uniprotkb:J1860(orf name)|uniprotkb:YJR084W(locus name)|uniprotkb:CSN12(gene name)|psi-mi:CSN12(display_short)	psi-mi:cep70_human(display_long)|uniprotkb:CEP70(gene name)|psi-mi:CEP70(display_short)|uniprotkb:BITE(gene name synonym)|uniprotkb:p10-binding protein(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552812|imex:IM-24995-3774	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012617.1|sgd:S000003844|dip:DIP-6710N|mint:P47130|ensemblfungi:YJR084W(gene)|ensemblfungi:YJR084W_mRNA(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000754"(adaptation of signaling pathway by response to pheromone involved in conjugation with cellular fusion)|go:"GO:0000973"(posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0070390"(transcription export complex 2)|go:"GO:0071033"|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR036388	ensembl:ENSG00000114107(gene)|ensembl:ENST00000264982(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|interpro:IPR019734|interpro:IPR037692|mint:Q8NHQ1|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|ensembl:ENST00000484888(transcript)|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_077817.2|refseq:XP_016862764.1|refseq:NP_001275893.1|refseq:NP_001275894.1|refseq:NP_001275895.1|refseq:NP_001275896.1|refseq:NP_001307527.1|refseq:NP_001307529.1	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:3mwOzmQkVCLzVvabW1WAjChHkg8559292	rogid:S4yveQWcvdVtAUX65gqrJ5Dv0Mc9606	intact-crc:B9A9F6528DA0C9D4|rigid:vZhLFDSYHDxeoMiZ7ixn8lWni20	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P53335	uniprotkb:Q8NHQ1	intact:EBI-23652|uniprotkb:D6VV57|uniprotkb:Q8TG89|intact:EBI-33325|ensemblfungi:YGR280C	intact:EBI-739624|ensembl:ENSP00000264982|ensembl:ENSP00000419231|uniprotkb:Q96B31|uniprotkb:Q9H2C3|uniprotkb:Q9H2Z1|uniprotkb:Q9H940|uniprotkb:D3DNE9|uniprotkb:B7Z5I8|uniprotkb:B7Z7E8|uniprotkb:F5GZX8	psi-mi:pxr1_yeast(display_long)|uniprotkb:PXR1(gene name)|psi-mi:PXR1(display_short)|uniprotkb:GNO1(gene name synonym)|uniprotkb:PinX1-related protein 1(gene name synonym)|uniprotkb:G-patch nucleolar protein(gene name synonym)|uniprotkb:YGR280C(locus name)	psi-mi:cep70_human(display_long)|uniprotkb:CEP70(gene name)|psi-mi:CEP70(display_short)|uniprotkb:BITE(gene name synonym)|uniprotkb:p10-binding protein(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552820|imex:IM-24995-3776	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011796.1|sgd:S000003512|dip:DIP-4308N|mint:P53335|ensemblfungi:YGR280C(gene)|ensemblfungi:YGR280C_mRNA(transcript)|go:"GO:0000494"(box C/D RNA 3'-end processing)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0010521"(telomerase inhibitor activity)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|interpro:IPR000467(D111/G-patch)	ensembl:ENSG00000114107(gene)|ensembl:ENST00000264982(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|interpro:IPR019734|interpro:IPR037692|mint:Q8NHQ1|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|ensembl:ENST00000484888(transcript)|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_077817.2|refseq:XP_016862764.1|refseq:NP_001275893.1|refseq:NP_001275894.1|refseq:NP_001275895.1|refseq:NP_001275896.1|refseq:NP_001307527.1|refseq:NP_001307529.1	-	crc64:D5AB6EB2C129922D	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:SzQtp13uvK3KbuNHyZQPJxKMzwY559292	rogid:S4yveQWcvdVtAUX65gqrJ5Dv0Mc9606	intact-crc:B57DB75BFF4E0274|rigid:w7ywsBjZq3ZfPloH3tu3ec70B7c	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8NHQ1	uniprotkb:P35180	intact:EBI-739624|ensembl:ENSP00000264982|ensembl:ENSP00000419231|uniprotkb:Q96B31|uniprotkb:Q9H2C3|uniprotkb:Q9H2Z1|uniprotkb:Q9H940|uniprotkb:D3DNE9|uniprotkb:B7Z5I8|uniprotkb:B7Z7E8|uniprotkb:F5GZX8	intact:EBI-12522|uniprotkb:D6VUL4|ensemblfungi:YGR082W	psi-mi:cep70_human(display_long)|uniprotkb:CEP70(gene name)|psi-mi:CEP70(display_short)|uniprotkb:BITE(gene name synonym)|uniprotkb:p10-binding protein(gene name synonym)	psi-mi:tom20_yeast(display_long)|uniprotkb:MOM19(gene name synonym)|uniprotkb:YGR082W(locus name)|uniprotkb:TOM20(gene name)|psi-mi:TOM20(display_short)|uniprotkb:MAS20(gene name synonym)|uniprotkb:Mitochondrial 20 kDa outer membrane protein(gene name synonym)|uniprotkb:Translocase of outer membrane 20 kDa subunit(gene name synonym)|uniprotkb:Protein MAS20(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552816|imex:IM-24995-3775	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114107(gene)|ensembl:ENST00000264982(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|interpro:IPR019734|interpro:IPR037692|mint:Q8NHQ1|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|ensembl:ENST00000484888(transcript)|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_077817.2|refseq:XP_016862764.1|refseq:NP_001275893.1|refseq:NP_001275894.1|refseq:NP_001275895.1|refseq:NP_001275896.1|refseq:NP_001307527.1|refseq:NP_001307529.1	ensemblfungi:YGR082W(gene)|ensemblfungi:YGR082W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005742"(mitochondrial outer membrane translocase complex)|go:"GO:0016031"(tRNA import into mitochondrion)|go:"GO:0030150"(protein import into mitochondrial matrix)|go:"GO:0030943"(mitochondrion targeting sequence binding)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|interpro:IPR002056(Protein import receptor MAS20)|interpro:IPR023392|refseq:NP_011596.1|sgd:S000003314|dip:DIP-2539N|mint:P35180	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:S4yveQWcvdVtAUX65gqrJ5Dv0Mc9606	rogid:7U00YLVWcaegWlJEKzGblv6STx4559292	intact-crc:EC82EF59D3C29145|rigid:z7WBjT6L0UwP5vPIEbn0OubQKjM	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q02724	uniprotkb:Q8NHQ1	intact:EBI-20050|uniprotkb:D6W3Z2|ensemblfungi:YPL020C	intact:EBI-739624|ensembl:ENSP00000264982|ensembl:ENSP00000419231|uniprotkb:Q96B31|uniprotkb:Q9H2C3|uniprotkb:Q9H2Z1|uniprotkb:Q9H940|uniprotkb:D3DNE9|uniprotkb:B7Z5I8|uniprotkb:B7Z7E8|uniprotkb:F5GZX8	psi-mi:ulp1_yeast(display_long)|uniprotkb:ULP1(gene name)|psi-mi:ULP1(display_short)|uniprotkb:LPB11C(orf name)|uniprotkb:YPL020C(locus name)	psi-mi:cep70_human(display_long)|uniprotkb:CEP70(gene name)|psi-mi:CEP70(display_short)|uniprotkb:BITE(gene name synonym)|uniprotkb:p10-binding protein(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552824|imex:IM-24995-3777	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015305.1|sgd:S000005941|ensemblfungi:YPL020C(gene)|ensemblfungi:YPL020C_mRNA(transcript)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005730"(nucleolus)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0016926"(protein desumoylation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070140"(SUMO-specific isopeptidase activity)|interpro:IPR003653(Peptidase C48, SUMO/Sentrin/Ubl1)|interpro:IPR038765|rcsb pdb:1EUV|rcsb pdb:2HKP|rcsb pdb:2HL8|rcsb pdb:2HL9|rcsb pdb:5H2V|rcsb pdb:5H2W|rcsb pdb:5H2X|reactome:R-SCE-3065679|reactome:R-SCE-6791226|dip:DIP-4041N|mint:Q02724	ensembl:ENSG00000114107(gene)|ensembl:ENST00000264982(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|interpro:IPR019734|interpro:IPR037692|mint:Q8NHQ1|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|ensembl:ENST00000484888(transcript)|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_077817.2|refseq:XP_016862764.1|refseq:NP_001275893.1|refseq:NP_001275894.1|refseq:NP_001275895.1|refseq:NP_001275896.1|refseq:NP_001307527.1|refseq:NP_001307529.1	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:H9B4qZf/ZMbHr7u4hbtR4fzz0ec559292	rogid:S4yveQWcvdVtAUX65gqrJ5Dv0Mc9606	intact-crc:048C271914A3C938|rigid:f93dJ2zT3oTwvFJuKkqvhFFZJkU	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P47041	uniprotkb:Q8NHQ1	intact:EBI-25889|uniprotkb:D6VWC4|ensemblfungi:YJL058C	intact:EBI-739624|ensembl:ENSP00000264982|ensembl:ENSP00000419231|uniprotkb:Q96B31|uniprotkb:Q9H2C3|uniprotkb:Q9H2Z1|uniprotkb:Q9H940|uniprotkb:D3DNE9|uniprotkb:B7Z5I8|uniprotkb:B7Z7E8|uniprotkb:F5GZX8	psi-mi:bit61_yeast(display_long)|uniprotkb:YJL058C(locus name)|uniprotkb:J1141(orf name)|uniprotkb:61 kDa binding partner of TOR2 protein(gene name synonym)|uniprotkb:BIT61(gene name)|psi-mi:BIT61(display_short)	psi-mi:cep70_human(display_long)|uniprotkb:CEP70(gene name)|psi-mi:CEP70(display_short)|uniprotkb:BITE(gene name synonym)|uniprotkb:p10-binding protein(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552848|imex:IM-24995-3783	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012477.1|sgd:S000003594|dip:DIP-1444N|reactome:R-SCE-1257604|reactome:R-SCE-389357|reactome:R-SCE-5218920|ensemblfungi:YJL058C(gene)|ensemblfungi:YJL058C_mRNA(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005737"(cytoplasm)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0031932"(TORC2 complex)|go:"GO:0038203"(TORC2 signaling)|go:"GO:0071944"(cell periphery)|interpro:IPR013745(HbrB-like)|reactome:R-SCE-6804757	ensembl:ENSG00000114107(gene)|ensembl:ENST00000264982(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|interpro:IPR019734|interpro:IPR037692|mint:Q8NHQ1|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|ensembl:ENST00000484888(transcript)|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_077817.2|refseq:XP_016862764.1|refseq:NP_001275893.1|refseq:NP_001275894.1|refseq:NP_001275895.1|refseq:NP_001275896.1|refseq:NP_001307527.1|refseq:NP_001307529.1	-	crc64:99F0F96840311F4B	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:H+zcKwbWL90wsmvD9TfWYmEbRwM559292	rogid:S4yveQWcvdVtAUX65gqrJ5Dv0Mc9606	intact-crc:B7B8264586FD360D|rigid:wRL/cjvgWWdYQhzhnRhUzoozCiY	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P40348	uniprotkb:Q8NHQ1	intact:EBI-14992|uniprotkb:E9P8U1|uniprotkb:D6VWN9|ensemblfungi:YJR068W	intact:EBI-739624|ensembl:ENSP00000264982|ensembl:ENSP00000419231|uniprotkb:Q96B31|uniprotkb:Q9H2C3|uniprotkb:Q9H2Z1|uniprotkb:Q9H940|uniprotkb:D3DNE9|uniprotkb:B7Z5I8|uniprotkb:B7Z7E8|uniprotkb:F5GZX8	psi-mi:rfc2_yeast(display_long)|uniprotkb:RFC2(gene name)|psi-mi:RFC2(display_short)|uniprotkb:YJR068W(locus name)|uniprotkb:J1808(orf name)|uniprotkb:Activator 1 41 kDa subunit(gene name synonym)	psi-mi:cep70_human(display_long)|uniprotkb:CEP70(gene name)|psi-mi:CEP70(display_short)|uniprotkb:BITE(gene name synonym)|uniprotkb:p10-binding protein(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552836|imex:IM-24995-3780	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003829|refseq:NP_012602.3|ensemblfungi:YJR068W(gene)|ensemblfungi:YJR068W_mRNA(transcript)|go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005663"(DNA replication factor C complex)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006272"(leading strand elongation)|go:"GO:0006281"(DNA repair)|go:"GO:0006298"(mismatch repair)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0031389"(Rad17 RFC-like complex)|go:"GO:0031390"(Ctf18 RFC-like complex)|go:"GO:0031391"(Elg1 RFC-like complex)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR013748(Replication factor C)|interpro:IPR027417|rcsb pdb:1SXJ|reactome:R-SCE-110312|reactome:R-SCE-110320|reactome:R-SCE-176187|reactome:R-SCE-5655862|reactome:R-SCE-5656121|reactome:R-SCE-5656169|reactome:R-SCE-5696397|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-69091|dip:DIP-2528N|mint:P40348	ensembl:ENSG00000114107(gene)|ensembl:ENST00000264982(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|interpro:IPR019734|interpro:IPR037692|mint:Q8NHQ1|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|ensembl:ENST00000484888(transcript)|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_077817.2|refseq:XP_016862764.1|refseq:NP_001275893.1|refseq:NP_001275894.1|refseq:NP_001275895.1|refseq:NP_001275896.1|refseq:NP_001307527.1|refseq:NP_001307529.1	-	crc64:59B2C4223B0D13BF	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:Z0Rwf5Gg3mAcfGIC8toCXrjnD2g559292	rogid:S4yveQWcvdVtAUX65gqrJ5Dv0Mc9606	intact-crc:7613B56DEAFD6665|rigid:ZQXGmLKGNXI8B5Paj1yQo5BBS6A	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P41911	uniprotkb:Q8NHQ1	intact:EBI-7791|uniprotkb:P50905|uniprotkb:D6W208|ensemblfungi:YOL059W	intact:EBI-739624|ensembl:ENSP00000264982|ensembl:ENSP00000419231|uniprotkb:Q96B31|uniprotkb:Q9H2C3|uniprotkb:Q9H2Z1|uniprotkb:Q9H940|uniprotkb:D3DNE9|uniprotkb:B7Z5I8|uniprotkb:B7Z7E8|uniprotkb:F5GZX8	psi-mi:gpd2_yeast(display_long)|uniprotkb:GPD2(gene name)|psi-mi:GPD2(display_short)|uniprotkb:GPD3(gene name synonym)|uniprotkb:YOL059W(locus name)|uniprotkb:O1222(orf name)	psi-mi:cep70_human(display_long)|uniprotkb:CEP70(gene name)|psi-mi:CEP70(display_short)|uniprotkb:BITE(gene name synonym)|uniprotkb:p10-binding protein(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552840|imex:IM-24995-3781	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014582.1|sgd:S000005420|dip:DIP-1348N|mint:P41911|ensemblfungi:YOL059W(gene)|ensemblfungi:YOL059W_mRNA(transcript)|go:"GO:0004367"(glycerol-3-phosphate dehydrogenase [NAD+] activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006071"(glycerol metabolic process)|go:"GO:0006072"(glycerol-3-phosphate metabolic process)|go:"GO:0006116"(NADH oxidation)|go:"GO:0009331"(glycerol-3-phosphate dehydrogenase complex)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046168"(glycerol-3-phosphate catabolic process)|go:"GO:0051287"(NAD binding)|interpro:IPR006109(NAD-dependent glycerol-3-phosphate dehydrogenase, C-terminal)|interpro:IPR006168(NAD-dependent glycerol-3-phosphate dehydrogenase)|interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|interpro:IPR011128(NAD-dependent glycerol-3-phosphate dehydrogenase, N-terminal)|interpro:IPR013328(Dehydrogenase, multihelical)|interpro:IPR017751(NAD-dependent glycerol-3-phosphate dehydrogenase, eukaryotic)|interpro:IPR036291|reactome:R-SCE-1483166	ensembl:ENSG00000114107(gene)|ensembl:ENST00000264982(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|interpro:IPR019734|interpro:IPR037692|mint:Q8NHQ1|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|ensembl:ENST00000484888(transcript)|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_077817.2|refseq:XP_016862764.1|refseq:NP_001275893.1|refseq:NP_001275894.1|refseq:NP_001275895.1|refseq:NP_001275896.1|refseq:NP_001307527.1|refseq:NP_001307529.1	-	crc64:FA6C07034D3EC720	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:RX8TddHnpQdQdh6KN8y9IR8Jgrg559292	rogid:S4yveQWcvdVtAUX65gqrJ5Dv0Mc9606	intact-crc:4F89A62B8CC03CE3|rigid:Iu233k8WKSMtbV2xCJgemKCwEHI	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8NHQ1	uniprotkb:P20053	intact:EBI-739624|ensembl:ENSP00000264982|ensembl:ENSP00000419231|uniprotkb:Q96B31|uniprotkb:Q9H2C3|uniprotkb:Q9H2Z1|uniprotkb:Q9H940|uniprotkb:D3DNE9|uniprotkb:B7Z5I8|uniprotkb:B7Z7E8|uniprotkb:F5GZX8	intact:EBI-219|uniprotkb:D6W4H8|ensemblfungi:YPR178W	psi-mi:cep70_human(display_long)|uniprotkb:CEP70(gene name)|psi-mi:CEP70(display_short)|uniprotkb:BITE(gene name synonym)|uniprotkb:p10-binding protein(gene name synonym)	psi-mi:prp4_yeast(display_long)|uniprotkb:PRP4(gene name)|psi-mi:PRP4(display_short)|uniprotkb:RNA4(gene name synonym)|uniprotkb:YPR178W(locus name)|uniprotkb:P9705.6(orf name)|uniprotkb:Pre-mRNA-processing protein 4(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552844|imex:IM-24995-3782	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114107(gene)|ensembl:ENST00000264982(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|interpro:IPR019734|interpro:IPR037692|mint:Q8NHQ1|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|ensembl:ENST00000484888(transcript)|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_077817.2|refseq:XP_016862764.1|refseq:NP_001275893.1|refseq:NP_001275894.1|refseq:NP_001275895.1|refseq:NP_001275896.1|refseq:NP_001307527.1|refseq:NP_001307529.1	refseq:NP_015504.1|sgd:S000006382|mint:P20053|dip:DIP-2607N|ensemblfungi:YPR178W(gene)|ensemblfungi:YPR178W_mRNA(transcript)|go:"GO:0000393"(spliceosomal conformational changes to generate catalytic conformation)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0030621"(U4 snRNA binding)|go:"GO:0034247"(snoRNA splicing)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR014906("Pre-mRNA processing factor 4 (PRP4) like")|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|rcsb pdb:3JCM|rcsb pdb:5GAN|rcsb pdb:5GAP|rcsb pdb:5NRL|rcsb pdb:5ZWM|rcsb pdb:5ZWO	-	-	crc64:7CCCA3A92AC0CE78	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:S4yveQWcvdVtAUX65gqrJ5Dv0Mc9606	rogid:vvz5G0rqqyrugTvAPelDKit9FpQ559292	intact-crc:4D54E2A8A6D46E4A|rigid:bYutni7rDWOdZwLAyW9uUowQ90M	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P38340	uniprotkb:Q8NHQ1-3	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-11526150|ensembl:ENSP00000419743	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:q8nhq1-3(display_long)|uniprotkb:CEP70(gene name)|psi-mi:CEP70(display_short)|uniprotkb:BITE(gene name synonym)|uniprotkb:p10-binding protein(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552872|imex:IM-24995-3789	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F	ensembl:ENSG00000114107(gene)|ensembl:ENST00000464035(transcript)|intact:EBI-739624(isoform-parent)|uniprotkb:Q8NHQ1-3(isoform-parent)	-	crc64:66699F37B0013088	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:hoF4iYo+GzWQ21hoaWZfTftWKCc9606	intact-crc:7EC1C7B5210FF3BE|rigid:VGCTdbYQlaQljsg+888qhNQjDFE	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8NHQ1	uniprotkb:Q06411	intact:EBI-739624|ensembl:ENSP00000264982|ensembl:ENSP00000419231|uniprotkb:Q96B31|uniprotkb:Q9H2C3|uniprotkb:Q9H2Z1|uniprotkb:Q9H940|uniprotkb:D3DNE9|uniprotkb:B7Z5I8|uniprotkb:B7Z7E8|uniprotkb:F5GZX8	intact:EBI-576|uniprotkb:D6VZ60|ensemblfungi:YLR424W	psi-mi:cep70_human(display_long)|uniprotkb:CEP70(gene name)|psi-mi:CEP70(display_short)|uniprotkb:BITE(gene name synonym)|uniprotkb:p10-binding protein(gene name synonym)	psi-mi:sp382_yeast(display_long)|uniprotkb:NTR1(gene name synonym)|uniprotkb:YLR424W(locus name)|uniprotkb:SPP382(gene name)|psi-mi:SPP382(display_short)|uniprotkb:CCF8(gene name synonym)|uniprotkb:Suppressor of PRP38 protein 2(gene name synonym)|uniprotkb:Nineteen complex-related protein 1(gene name synonym)|uniprotkb:CLF1 complex factor 8(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552868|imex:IM-24995-3788	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114107(gene)|ensembl:ENST00000264982(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|interpro:IPR019734|interpro:IPR037692|mint:Q8NHQ1|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|ensembl:ENST00000484888(transcript)|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_077817.2|refseq:XP_016862764.1|refseq:NP_001275893.1|refseq:NP_001275894.1|refseq:NP_001275895.1|refseq:NP_001275896.1|refseq:NP_001307527.1|refseq:NP_001307529.1	refseq:NP_013528.1|sgd:S000004416|dip:DIP-1491N|mint:Q06411|ensemblfungi:YLR424W(gene)|ensemblfungi:YLR424W_mRNA(transcript)|go:"GO:0000349"(generation of catalytic spliceosome for first transesterification step)|go:"GO:0000390"(spliceosomal complex disassembly)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0071008"(U2-type post-mRNA release spliceosomal complex)|go:"GO:1904876"(negative regulation of DNA ligase activity)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR000467(D111/G-patch)|rcsb pdb:5Y88	-	-	crc64:9986B547B9582338	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:S4yveQWcvdVtAUX65gqrJ5Dv0Mc9606	rogid:HrG54vTE2zs7jxPSzi+9eeA23/k559292	intact-crc:05C1A13D183B3F88|rigid:8gVaAftn5+nVBMvX2UnEShT6XlE	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P28004	uniprotkb:Q8NHQ1	intact:EBI-20640|uniprotkb:D6VPI6|ensemblfungi:YAL032C	intact:EBI-739624|ensembl:ENSP00000264982|ensembl:ENSP00000419231|uniprotkb:Q96B31|uniprotkb:Q9H2C3|uniprotkb:Q9H2Z1|uniprotkb:Q9H940|uniprotkb:D3DNE9|uniprotkb:B7Z5I8|uniprotkb:B7Z7E8|uniprotkb:F5GZX8	psi-mi:prp45_yeast(display_long)|uniprotkb:YAL032C(locus name)|uniprotkb:PRP45(gene name)|psi-mi:PRP45(display_short)|uniprotkb:FUN20(gene name synonym)	psi-mi:cep70_human(display_long)|uniprotkb:CEP70(gene name)|psi-mi:CEP70(display_short)|uniprotkb:BITE(gene name synonym)|uniprotkb:p10-binding protein(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552852|imex:IM-24995-3784	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009370.1|sgd:S000000030|ensemblfungi:YAL032C(gene)|ensemblfungi:YAL032C_mRNA(transcript)|go:"GO:0000350"(generation of catalytic spliceosome for second transesterification step)|go:"GO:0005634"(nucleus)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|interpro:IPR004015(SKIP/SNW)|interpro:IPR017862|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|dip:DIP-2774N|mint:P28004	ensembl:ENSG00000114107(gene)|ensembl:ENST00000264982(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|interpro:IPR019734|interpro:IPR037692|mint:Q8NHQ1|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|ensembl:ENST00000484888(transcript)|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_077817.2|refseq:XP_016862764.1|refseq:NP_001275893.1|refseq:NP_001275894.1|refseq:NP_001275895.1|refseq:NP_001275896.1|refseq:NP_001307527.1|refseq:NP_001307529.1	-	crc64:FE5A724186D7FE84	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:qoHF1UsO3k+JOTOfigSuy2P84/k559292	rogid:S4yveQWcvdVtAUX65gqrJ5Dv0Mc9606	intact-crc:86C663DB9B1608D7|rigid:SN4sk0rmyaezL9EELRiB8gngOQ0	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
intact:EBI-11522371	uniprotkb:Q8NHQ1	-	intact:EBI-739624|ensembl:ENSP00000264982|ensembl:ENSP00000419231|uniprotkb:Q96B31|uniprotkb:Q9H2C3|uniprotkb:Q9H2Z1|uniprotkb:Q9H940|uniprotkb:D3DNE9|uniprotkb:B7Z5I8|uniprotkb:B7Z7E8|uniprotkb:F5GZX8	psi-mi:yjr003c(display_short)|psi-mi:EBI-11522371(display_long)	psi-mi:cep70_human(display_long)|uniprotkb:CEP70(gene name)|psi-mi:CEP70(display_short)|uniprotkb:BITE(gene name synonym)|uniprotkb:p10-binding protein(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552860|imex:IM-24995-3786	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSG00000114107(gene)|ensembl:ENST00000264982(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|interpro:IPR019734|interpro:IPR037692|mint:Q8NHQ1|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|ensembl:ENST00000484888(transcript)|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_077817.2|refseq:XP_016862764.1|refseq:NP_001275893.1|refseq:NP_001275894.1|refseq:NP_001275895.1|refseq:NP_001275896.1|refseq:NP_001307527.1|refseq:NP_001307529.1	-	no-uniprot-update:	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:dYGrrP3JnrXO2rj4v/nTT64la6A4932	rogid:S4yveQWcvdVtAUX65gqrJ5Dv0Mc9606	intact-crc:F6850AFC89915DCF|rigid:jjEF/VSJJhKBsAhjrSDzZiMDUfo	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q03338	uniprotkb:Q8NHQ1	intact:EBI-421|uniprotkb:D6VT97|ensemblfungi:YDR473C	intact:EBI-739624|ensembl:ENSP00000264982|ensembl:ENSP00000419231|uniprotkb:Q96B31|uniprotkb:Q9H2C3|uniprotkb:Q9H2Z1|uniprotkb:Q9H940|uniprotkb:D3DNE9|uniprotkb:B7Z5I8|uniprotkb:B7Z7E8|uniprotkb:F5GZX8	psi-mi:prp3_yeast(display_long)|uniprotkb:PRP3(gene name)|psi-mi:PRP3(display_short)|uniprotkb:RNA3(gene name synonym)|uniprotkb:YDR473C(locus name)|uniprotkb:D8035.16(orf name)|uniprotkb:Pre-mRNA-splicing factor 3(gene name synonym)	psi-mi:cep70_human(display_long)|uniprotkb:CEP70(gene name)|psi-mi:CEP70(display_short)|uniprotkb:BITE(gene name synonym)|uniprotkb:p10-binding protein(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552856|imex:IM-24995-3785	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002881|refseq:NP_010761.3|ensemblfungi:YDR473C(gene)|ensemblfungi:YDR473C_mRNA(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|interpro:IPR010541(Protein of unknown function DUF1115)|interpro:IPR013881(Pre-mRNA-splicing factor 3)|interpro:IPR027104|rcsb pdb:3JCM|rcsb pdb:4YHU|rcsb pdb:4YHV|rcsb pdb:4YHW|rcsb pdb:5GAN|rcsb pdb:5GAP|rcsb pdb:5NRL|rcsb pdb:5ZWM|rcsb pdb:5ZWO|dip:DIP-5266N|mint:Q03338	ensembl:ENSG00000114107(gene)|ensembl:ENST00000264982(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|interpro:IPR019734|interpro:IPR037692|mint:Q8NHQ1|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|ensembl:ENST00000484888(transcript)|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_077817.2|refseq:XP_016862764.1|refseq:NP_001275893.1|refseq:NP_001275894.1|refseq:NP_001275895.1|refseq:NP_001275896.1|refseq:NP_001307527.1|refseq:NP_001307529.1	-	crc64:E977FD9F708BDD91	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:KE0Y/kRXTq9LXt4PGsKnRcY7Sqg559292	rogid:S4yveQWcvdVtAUX65gqrJ5Dv0Mc9606	intact-crc:6378FDEA0E86D692|rigid:EVMV9nZXPApYzcEVft+zDK3DXyo	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8NHQ1	uniprotkb:P40507	intact:EBI-739624|ensembl:ENSP00000264982|ensembl:ENSP00000419231|uniprotkb:Q96B31|uniprotkb:Q9H2C3|uniprotkb:Q9H2Z1|uniprotkb:Q9H940|uniprotkb:D3DNE9|uniprotkb:B7Z5I8|uniprotkb:B7Z7E8|uniprotkb:F5GZX8	intact:EBI-25083|uniprotkb:D6VVK5|ensemblfungi:YIL079C	psi-mi:cep70_human(display_long)|uniprotkb:CEP70(gene name)|psi-mi:CEP70(display_short)|uniprotkb:BITE(gene name synonym)|uniprotkb:p10-binding protein(gene name synonym)	psi-mi:air1_yeast(display_long)|uniprotkb:Arginine methyltransferase-interacting RING finger protein 1(gene name synonym)|uniprotkb:AIR1(gene name)|psi-mi:AIR1(display_short)|uniprotkb:YIL079C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552864|imex:IM-24995-3787	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114107(gene)|ensembl:ENST00000264982(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|interpro:IPR019734|interpro:IPR037692|mint:Q8NHQ1|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|ensembl:ENST00000484888(transcript)|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_077817.2|refseq:XP_016862764.1|refseq:NP_001275893.1|refseq:NP_001275894.1|refseq:NP_001275895.1|refseq:NP_001275896.1|refseq:NP_001307527.1|refseq:NP_001307529.1	refseq:NP_012186.1|sgd:S000001341|mint:P40507|dip:DIP-2700N|ensemblfungi:YIL079C(gene)|ensemblfungi:YIL079C_mRNA(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031499"(TRAMP complex)|go:"GO:0043629"(ncRNA polyadenylation)|go:"GO:0071031"(nuclear mRNA surveillance of mRNA 3'-end processing)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071036"(nuclear polyadenylation-dependent snoRNA catabolic process)|go:"GO:0071037"(nuclear polyadenylation-dependent snRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071039"(nuclear polyadenylation-dependent CUT catabolic process)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR016713("Poly(A) polymerase complex, Air1/2")|interpro:IPR036875	-	-	crc64:3CA920FA1204EC9C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:S4yveQWcvdVtAUX65gqrJ5Dv0Mc9606	rogid:myPxXwP+mJgvoh50PLYk2Q3GMh4559292	intact-crc:49AEC30440C313AB|rigid:Hfww7CA+cje4UceaTeAirQcFeIg	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P28004	uniprotkb:Q8TAP6	intact:EBI-20640|uniprotkb:D6VPI6|ensemblfungi:YAL032C	intact:EBI-742887|ensembl:ENSP00000262127|uniprotkb:Q658N5|uniprotkb:Q9H9U7|uniprotkb:B0YJB2|uniprotkb:B4DXG5|uniprotkb:B4DZW1	psi-mi:prp45_yeast(display_long)|uniprotkb:YAL032C(locus name)|uniprotkb:PRP45(gene name)|psi-mi:PRP45(display_short)|uniprotkb:FUN20(gene name synonym)	psi-mi:cep76_human(display_long)|uniprotkb:CEP76(gene name)|psi-mi:CEP76(display_short)|uniprotkb:C18orf9(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552884|imex:IM-24995-3792	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009370.1|sgd:S000000030|ensemblfungi:YAL032C(gene)|ensemblfungi:YAL032C_mRNA(transcript)|go:"GO:0000350"(generation of catalytic spliceosome for second transesterification step)|go:"GO:0005634"(nucleus)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|interpro:IPR004015(SKIP/SNW)|interpro:IPR017862|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|dip:DIP-2774N|mint:P28004	refseq:NP_079175.2|ensembl:ENSG00000101624(gene)|ensembl:ENST00000262127(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0046599"(regulation of centriole replication)|interpro:IPR028926|interpro:IPR038765|mint:Q8TAP6|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_001258918.1	-	crc64:FE5A724186D7FE84	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:qoHF1UsO3k+JOTOfigSuy2P84/k559292	rogid:fWzb8oIU35oVWomyDrf8u5sbxUk9606	intact-crc:CFCC506072237E78|rigid:asauxzIqMwX/jnbHM8oNmdgnmJs	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P38340	uniprotkb:Q8TAP6	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-742887|ensembl:ENSP00000262127|uniprotkb:Q658N5|uniprotkb:Q9H9U7|uniprotkb:B0YJB2|uniprotkb:B4DXG5|uniprotkb:B4DZW1	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:cep76_human(display_long)|uniprotkb:CEP76(gene name)|psi-mi:CEP76(display_short)|uniprotkb:C18orf9(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552888|imex:IM-24995-3793	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F	refseq:NP_079175.2|ensembl:ENSG00000101624(gene)|ensembl:ENST00000262127(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0046599"(regulation of centriole replication)|interpro:IPR028926|interpro:IPR038765|mint:Q8TAP6|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_001258918.1	-	crc64:66699F37B0013088	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:fWzb8oIU35oVWomyDrf8u5sbxUk9606	intact-crc:56087BDE6BCD775F|rigid:b2+5OSmw5xO3lz9jgC8XS5gTSMk	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8NHQ1-3	uniprotkb:P32502	intact:EBI-11526150|ensembl:ENSP00000419743	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:q8nhq1-3(display_long)|uniprotkb:CEP70(gene name)|psi-mi:CEP70(display_short)|uniprotkb:BITE(gene name synonym)|uniprotkb:p10-binding protein(gene name synonym)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552876|imex:IM-24995-3790	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114107(gene)|ensembl:ENST00000464035(transcript)|intact:EBI-739624(isoform-parent)|uniprotkb:Q8NHQ1-3(isoform-parent)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731	-	-	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:hoF4iYo+GzWQ21hoaWZfTftWKCc9606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:7476BA10A3555A92|rigid:gvbOoDyvh55QDtfHDRmfUJrq5uI	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8TAP6	uniprotkb:P38792	intact:EBI-742887|ensembl:ENSP00000262127|uniprotkb:Q658N5|uniprotkb:Q9H9U7|uniprotkb:B0YJB2|uniprotkb:B4DXG5|uniprotkb:B4DZW1	intact:EBI-1757|uniprotkb:D3DL18|ensemblfungi:YHR069C	psi-mi:cep76_human(display_long)|uniprotkb:CEP76(gene name)|psi-mi:CEP76(display_short)|uniprotkb:C18orf9(gene name synonym)	psi-mi:rrp4_yeast(display_long)|uniprotkb:RRP4(gene name)|psi-mi:RRP4(display_short)|uniprotkb:Ribosomal RNA-processing protein 4(gene name synonym)|uniprotkb:YHR069C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552880|imex:IM-24995-3791	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_079175.2|ensembl:ENSG00000101624(gene)|ensembl:ENST00000262127(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0046599"(regulation of centriole replication)|interpro:IPR028926|interpro:IPR038765|mint:Q8TAP6|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_001258918.1	refseq:NP_011936.1|sgd:S000001111|dip:DIP-5888N|mint:P38792|ensemblfungi:YHR069C(gene)|ensemblfungi:YHR069C_mRNA(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0071034"(CUT catabolic process)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071049"|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR004088(K Homology, type 1)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR025721|interpro:IPR026699|interpro:IPR036612|rcsb pdb:4IFD|rcsb pdb:4OO1|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5G06|rcsb pdb:5JEA|rcsb pdb:5K36|rcsb pdb:5OKZ|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-429958|reactome:R-SCE-450385|reactome:R-SCE-450513|reactome:R-SCE-6791226	-	-	crc64:0718A7ABF42E9B9B	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:fWzb8oIU35oVWomyDrf8u5sbxUk9606	rogid:ZgBS9xjR7jC96sAb0m63ElPvM7M559292	intact-crc:745341D63DA025BC|rigid:FdK9E/hOr2p/p0E8zMPp69HfxXg	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P40302	uniprotkb:Q8TAP6	intact:EBI-13955|ensemblfungi:YMR314W|uniprotkb:D6W0E1	intact:EBI-742887|ensembl:ENSP00000262127|uniprotkb:Q658N5|uniprotkb:Q9H9U7|uniprotkb:B0YJB2|uniprotkb:B4DXG5|uniprotkb:B4DZW1	psi-mi:psa6_yeast(display_long)|uniprotkb:PRE5(gene name)|psi-mi:PRE5(display_short)|uniprotkb:YMR314W(locus name)|uniprotkb:YM9924.06(orf name)|uniprotkb:Proteasome component PRE5(gene name synonym)|uniprotkb:Macropain subunit PRE5(gene name synonym)|uniprotkb:Proteinase YSCE subunit PRE5(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit PRE5(gene name synonym)	psi-mi:cep76_human(display_long)|uniprotkb:CEP76(gene name)|psi-mi:CEP76(display_short)|uniprotkb:C18orf9(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552892|imex:IM-24995-3794	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:4Y8T|rcsb pdb:4Y8U|rcsb pdb:4Y9Y|rcsb pdb:4Y9Z|rcsb pdb:4YA0|rcsb pdb:4YA1|rcsb pdb:4YA2|rcsb pdb:4YA3|rcsb pdb:4YA4|rcsb pdb:4YA5|rcsb pdb:4Y7X|rcsb pdb:4Y7Y|rcsb pdb:4Y80|rcsb pdb:4Y81|rcsb pdb:4Y82|rcsb pdb:4Y84|rcsb pdb:4Y8G|rcsb pdb:4Y8H|rcsb pdb:4Y8I|rcsb pdb:4Y8J|rcsb pdb:4Y8K|rcsb pdb:4Y8L|rcsb pdb:4Y8M|rcsb pdb:4Y8N|rcsb pdb:4Y8O|rcsb pdb:4Y8P|rcsb pdb:4Y8Q|rcsb pdb:4Y8R|rcsb pdb:4Y8S|rcsb pdb:5FG7|rcsb pdb:5FG9|rcsb pdb:5FGA|rcsb pdb:4YA7|rcsb pdb:4YA9|rcsb pdb:4Z1L|rcsb pdb:5A5B|rcsb pdb:5AHJ|rcsb pdb:5BOU|rcsb pdb:5BXL|rcsb pdb:5BXN|rcsb pdb:5CGF|rcsb pdb:5CGG|rcsb pdb:5CGH|rcsb pdb:5CGI|rcsb pdb:5CZ4|rcsb pdb:5CZ5|rcsb pdb:5CZ6|rcsb pdb:5CZ7|rcsb pdb:5CZ8|rcsb pdb:5CZ9|rcsb pdb:5CZA|rcsb pdb:5D0S|rcsb pdb:5D0T|rcsb pdb:5D0V|rcsb pdb:5D0W|rcsb pdb:5D0X|rcsb pdb:5D0Z|rcsb pdb:5DKI|rcsb pdb:5DKJ|rcsb pdb:5FGD|rcsb pdb:3HYE|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:3MG0|rcsb pdb:3MG4|rcsb pdb:3MG6|rcsb pdb:3MG7|rcsb pdb:3MG8|rcsb pdb:3NZJ|rcsb pdb:3NZW|rcsb pdb:3NZX|rcsb pdb:3OEU|rcsb pdb:3OEV|rcsb pdb:3OKJ|rcsb pdb:3SDI|rcsb pdb:3SDK|rcsb pdb:3SHJ|rcsb pdb:3TDD|rcsb pdb:3UN4|rcsb pdb:3UN8|rcsb pdb:3WXR|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:4EU2|rcsb pdb:4FZC|rcsb pdb:4FZG|rcsb pdb:4G4S|rcsb pdb:4GK7|rcsb pdb:4HNP|rcsb pdb:4HRC|rcsb pdb:4HRD|rcsb pdb:4INR|rcsb pdb:4INT|rcsb pdb:4INU|rcsb pdb:4J70|rcsb pdb:4JSQ|rcsb pdb:4JSU|rcsb pdb:4JT0|rcsb pdb:4LQI|rcsb pdb:4LTC|rcsb pdb:4NNN|rcsb pdb:4NNW|rcsb pdb:4NO1|rcsb pdb:4NO6|rcsb pdb:4NO8|rcsb pdb:4NO9|rcsb pdb:5FGE|rcsb pdb:5FGF|rcsb pdb:5FGG|rcsb pdb:5FGH|rcsb pdb:5FGI|rcsb pdb:5FHS|rcsb pdb:5JHR|rcsb pdb:5JHS|rcsb pdb:5L52|rcsb pdb:5L54|rcsb pdb:5L55|rcsb pdb:5L5A|rcsb pdb:5L5B|rcsb pdb:5L5D|rcsb pdb:5L5E|rcsb pdb:5L5F|rcsb pdb:5L5H|rcsb pdb:5L5I|rcsb pdb:5L5J|rcsb pdb:5L5O|rcsb pdb:5L5P|rcsb pdb:5L5Q|rcsb pdb:5L5R|rcsb pdb:4Q1S|rcsb pdb:4QBY|rcsb pdb:4QLQ|rcsb pdb:4QLS|rcsb pdb:4QLT|rcsb pdb:4QLU|rcsb pdb:4QLV|rcsb pdb:4QUX|rcsb pdb:4QUY|rcsb pdb:4QV0|rcsb pdb:4QV1|rcsb pdb:4QV3|rcsb pdb:4QV4|rcsb pdb:4QV5|rcsb pdb:4QV6|rcsb pdb:4QV7|rcsb pdb:4QV8|rcsb pdb:4QV9|rcsb pdb:4QVL|ensemblfungi:YMR314W(gene)|ensemblfungi:YMR314W_mRNA(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0042175"(nuclear outer membrane-endoplasmic reticulum membrane network)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR035144|rcsb pdb:1FNT|rcsb pdb:1G0U|rcsb pdb:1G65|rcsb pdb:1JD2|rcsb pdb:1RYP|rcsb pdb:1Z7Q|rcsb pdb:2F16|rcsb pdb:2FAK|rcsb pdb:2GPL|rcsb pdb:2ZCY|rcsb pdb:3BDM|rcsb pdb:3D29|rcsb pdb:3DY3|rcsb pdb:3DY4|rcsb pdb:3E47|rcsb pdb:3GPJ|rcsb pdb:3GPT|rcsb pdb:3GPW|rcsb pdb:4QVM|rcsb pdb:4QVN|rcsb pdb:4QVP|rcsb pdb:4QVQ|rcsb pdb:4QVV|rcsb pdb:4QVW|rcsb pdb:4QVY|rcsb pdb:4QW0|rcsb pdb:4QW1|rcsb pdb:4QW3|rcsb pdb:4QW4|rcsb pdb:4QW5|rcsb pdb:4QW6|rcsb pdb:4QW7|rcsb pdb:4QWF|rcsb pdb:4QWG|rcsb pdb:4QWI|rcsb pdb:4QWJ|rcsb pdb:4QWK|rcsb pdb:4QWL|rcsb pdb:4QWR|rcsb pdb:4QWS|rcsb pdb:4QWU|rcsb pdb:4QWX|rcsb pdb:4QXJ|rcsb pdb:4QZ0|rcsb pdb:4QZ1|rcsb pdb:4QZ2|rcsb pdb:4QZ3|rcsb pdb:4QZ4|rcsb pdb:4QZ5|rcsb pdb:4QZ6|rcsb pdb:4QZ7|rcsb pdb:4QZW|rcsb pdb:4QZX|rcsb pdb:4QZZ|rcsb pdb:4R00|rcsb pdb:4R02|rcsb pdb:4R17|rcsb pdb:4R18|rcsb pdb:4RUR|rcsb pdb:4V7O|rcsb pdb:4X6Z|rcsb pdb:4Y69|rcsb pdb:4Y6A|rcsb pdb:4Y6V|rcsb pdb:4Y6Z|rcsb pdb:4Y70|rcsb pdb:4Y74|rcsb pdb:4Y75|rcsb pdb:4Y77|rcsb pdb:4Y78|rcsb pdb:4Y7W|rcsb pdb:5LTT|rcsb pdb:5M2B|rcsb pdb:5MP9|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5NIF|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6G7F|rcsb pdb:6G8M|rcsb pdb:6G8N|rcsb pdb:6GOP|rcsb pdb:6H39|rcsb pdb:6HTB|rcsb pdb:6HTC|rcsb pdb:6HTD|rcsb pdb:6HTP|rcsb pdb:6HTR|rcsb pdb:6HUB|rcsb pdb:6HUC|rcsb pdb:6HUQ|rcsb pdb:6HUU|rcsb pdb:6HUV|rcsb pdb:6HV3|rcsb pdb:6HV4|rcsb pdb:6HV5|rcsb pdb:6HV7|rcsb pdb:6HVA|rcsb pdb:6HVR|rcsb pdb:6HVS|rcsb pdb:6HVT|rcsb pdb:6HVU|rcsb pdb:6HVV|rcsb pdb:5L5S|rcsb pdb:5L5T|rcsb pdb:5L5U|rcsb pdb:5L5V|rcsb pdb:5L5W|rcsb pdb:5L5X|rcsb pdb:5L5Y|rcsb pdb:5L5Z|rcsb pdb:5L60|rcsb pdb:5L61|rcsb pdb:5L62|rcsb pdb:5L63|rcsb pdb:5L64|rcsb pdb:5L65|rcsb pdb:5L66|rcsb pdb:5L67|rcsb pdb:5L68|rcsb pdb:5L69|rcsb pdb:5L6A|rcsb pdb:5L6B|rcsb pdb:5L6C|rcsb pdb:5LAI|rcsb pdb:5LAJ|rcsb pdb:6HVW|rcsb pdb:6HVX|rcsb pdb:6HVY|rcsb pdb:6HW0|rcsb pdb:6HW3|rcsb pdb:6HW4|rcsb pdb:6HW5|rcsb pdb:6HW6|rcsb pdb:6HW7|rcsb pdb:6HW8|rcsb pdb:6HW9|rcsb pdb:6HWA|rcsb pdb:6HWB|rcsb pdb:6HWC|rcsb pdb:6HWD|rcsb pdb:6HWE|rcsb pdb:6HWF|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2X|rcsb pdb:6J30|rcsb pdb:6ZOU|rcsb pdb:6ZP6|rcsb pdb:6ZP8|rcsb pdb:7LS5|rcsb pdb:7LS6|rcsb pdb:7LSX|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|rcsb pdb:6J2Q|refseq:NP_014045.1|sgd:S000004931|mint:P40302|dip:DIP-1528N	refseq:NP_079175.2|ensembl:ENSG00000101624(gene)|ensembl:ENST00000262127(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0046599"(regulation of centriole replication)|interpro:IPR028926|interpro:IPR038765|mint:Q8TAP6|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_001258918.1	-	crc64:C43CBCC1C6B9E39E	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:C9GPb0JAklkBz0t/YYqRMNEiQss559292	rogid:fWzb8oIU35oVWomyDrf8u5sbxUk9606	intact-crc:ADA309F705C27E0A|rigid:DHzAsX9ZS6IcNW2eAj2hsBeJhXE	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P13130	uniprotkb:Q8TAP6	intact:EBI-11523294|uniprotkb:D3DL88|ensemblfungi:YHR139C	intact:EBI-742887|ensembl:ENSP00000262127|uniprotkb:Q658N5|uniprotkb:Q9H9U7|uniprotkb:B0YJB2|uniprotkb:B4DXG5|uniprotkb:B4DZW1	psi-mi:ss100_yeast(display_long)|uniprotkb:SPS100(gene name)|psi-mi:SPS100(display_short)|uniprotkb:YHR139C(locus name)	psi-mi:cep76_human(display_long)|uniprotkb:CEP76(gene name)|psi-mi:CEP76(display_short)|uniprotkb:C18orf9(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552896|imex:IM-24995-3795	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR006034(Asparaginase/glutaminase)|refseq:NP_012007.1|sgd:S000001181|ensemblfungi:YHR139C(gene)|ensemblfungi:YHR139C_mRNA(transcript)|go:"GO:0030476"(ascospore wall assembly)|interpro:IPR036152	refseq:NP_079175.2|ensembl:ENSG00000101624(gene)|ensembl:ENST00000262127(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0046599"(regulation of centriole replication)|interpro:IPR028926|interpro:IPR038765|mint:Q8TAP6|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_001258918.1	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/03/16	rogid:ThKMilyLHPEAiJu+3ty4DXcUEE4559292	rogid:fWzb8oIU35oVWomyDrf8u5sbxUk9606	intact-crc:E70EECDA5116829D|rigid:YRjep4LcIYNbHrjtIgVJr+fIq6A	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q07379	uniprotkb:Q8TAP6	intact:EBI-2342994|uniprotkb:D6VRT9|ensemblfungi:YDL057W	intact:EBI-742887|ensembl:ENSP00000262127|uniprotkb:Q658N5|uniprotkb:Q9H9U7|uniprotkb:B0YJB2|uniprotkb:B4DXG5|uniprotkb:B4DZW1	psi-mi:yd057_yeast(display_long)|uniprotkb:YDL057W(locus name)	psi-mi:cep76_human(display_long)|uniprotkb:CEP76(gene name)|psi-mi:CEP76(display_short)|uniprotkb:C18orf9(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552912|imex:IM-24995-3799	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002215|refseq:NP_010226.1|interpro:IPR022742|interpro:IPR029058|ensemblfungi:YDL057W(gene)|ensemblfungi:YDL057W_mRNA(transcript)|go:"GO:0016020"(membrane)|go:"GO:0016298"(lipase activity)	refseq:NP_079175.2|ensembl:ENSG00000101624(gene)|ensembl:ENST00000262127(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0046599"(regulation of centriole replication)|interpro:IPR028926|interpro:IPR038765|mint:Q8TAP6|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_001258918.1	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:U0Sf+t16Ti+vYEOEePrGjlqflhQ559292	rogid:fWzb8oIU35oVWomyDrf8u5sbxUk9606	intact-crc:40CF10F155A57CAA|rigid:aenOWHEG1ZfDrZNsCYxMcOs3fd4	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P38828	uniprotkb:Q8TAP6	intact:EBI-24700|uniprotkb:D3DL71|ensemblfungi:YHR121W	intact:EBI-742887|ensembl:ENSP00000262127|uniprotkb:Q658N5|uniprotkb:Q9H9U7|uniprotkb:B0YJB2|uniprotkb:B4DXG5|uniprotkb:B4DZW1	psi-mi:lsm12_yeast(display_long)|uniprotkb:YHR121W(locus name)|uniprotkb:LSM12(gene name)|psi-mi:LSM12(display_short)|uniprotkb:Sm-like protein 12(gene name synonym)	psi-mi:cep76_human(display_long)|uniprotkb:CEP76(gene name)|psi-mi:CEP76(display_short)|uniprotkb:C18orf9(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552900|imex:IM-24995-3796	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011989.1|sgd:S000001163|dip:DIP-5545N|mint:P38828|ensemblfungi:YHR121W(gene)|ensemblfungi:YHR121W_mRNA(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016070"(RNA metabolic process)|interpro:IPR016521(Uncharacterised conserved protein UCP007783, YHR121w)|interpro:IPR019181|interpro:IPR039683	refseq:NP_079175.2|ensembl:ENSG00000101624(gene)|ensembl:ENST00000262127(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0046599"(regulation of centriole replication)|interpro:IPR028926|interpro:IPR038765|mint:Q8TAP6|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_001258918.1	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:6xw9WGjtFwkmKlO6QHoSSS2aMro559292	rogid:fWzb8oIU35oVWomyDrf8u5sbxUk9606	intact-crc:E564AD009A1D89FF|rigid:4MdpdXBICplRwkaqS7/1NVvtVeQ	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P32502	uniprotkb:Q8TAP6	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	intact:EBI-742887|ensembl:ENSP00000262127|uniprotkb:Q658N5|uniprotkb:Q9H9U7|uniprotkb:B0YJB2|uniprotkb:B4DXG5|uniprotkb:B4DZW1	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:cep76_human(display_long)|uniprotkb:CEP76(gene name)|psi-mi:CEP76(display_short)|uniprotkb:C18orf9(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552904|imex:IM-24995-3797	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731	refseq:NP_079175.2|ensembl:ENSG00000101624(gene)|ensembl:ENST00000262127(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0046599"(regulation of centriole replication)|interpro:IPR028926|interpro:IPR038765|mint:Q8TAP6|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_001258918.1	-	crc64:A5409FAF1594854C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	rogid:fWzb8oIU35oVWomyDrf8u5sbxUk9606	intact-crc:1526EE8258B36B10|rigid:xIEW9O53WNj98bB1gVHS61fa9CM	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P38263	uniprotkb:Q8TAP6	intact:EBI-20304|uniprotkb:D6VQA4|ensemblfungi:YBR105C	intact:EBI-742887|ensembl:ENSP00000262127|uniprotkb:Q658N5|uniprotkb:Q9H9U7|uniprotkb:B0YJB2|uniprotkb:B4DXG5|uniprotkb:B4DZW1	psi-mi:gid4_yeast(display_long)|uniprotkb:VID24(gene name)|psi-mi:VID24(display_short)|uniprotkb:YBR105C(locus name)|uniprotkb:YBR0834(orf name)|uniprotkb:GID4(gene name synonym)|uniprotkb:Glucose-induced degradation protein 4(gene name synonym)	psi-mi:cep76_human(display_long)|uniprotkb:CEP76(gene name)|psi-mi:CEP76(display_short)|uniprotkb:C18orf9(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552908|imex:IM-24995-3798	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009663.1|sgd:S000000309|ensemblfungi:YBR105C(gene)|ensemblfungi:YBR105C_mRNA(transcript)|go:"GO:0005773"(vacuole)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0007039"(protein catabolic process in the vacuole)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034657"(GID complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045721"(negative regulation of gluconeogenesis)|go:"GO:0071596"(ubiquitin-dependent protein catabolic process via the N-end rule pathway)|interpro:IPR018618|rcsb pdb:6SWY|dip:DIP-4502N|mint:P38263	refseq:NP_079175.2|ensembl:ENSG00000101624(gene)|ensembl:ENST00000262127(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0046599"(regulation of centriole replication)|interpro:IPR028926|interpro:IPR038765|mint:Q8TAP6|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_001258918.1	-	crc64:FF020B239676E0B2	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:ag6caXMIP/qIv27yJtSEmlBoI7g559292	rogid:fWzb8oIU35oVWomyDrf8u5sbxUk9606	intact-crc:FB37D98DC359E364|rigid:ZDC0HXWv5sC1tHgjF4wrRkR6x2Q	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P25631	uniprotkb:Q8TBB1	intact:EBI-2347265|uniprotkb:D6VR59|ensemblfungi:YCR051W	intact:EBI-739832|uniprotkb:Q4W5K7|uniprotkb:Q8N4C2|uniprotkb:Q96MJ7|uniprotkb:Q9BY20|ensembl:ENSP00000263925	psi-mi:ycu1_yeast(display_long)|uniprotkb:YCR51W(orf name)|uniprotkb:YCR051W(locus name)	psi-mi:lnx1_human(display_long)|uniprotkb:LNX1(gene name)|psi-mi:LNX1(display_short)|uniprotkb:LNX(gene name synonym)|uniprotkb:Numb-binding protein 1(gene name synonym)|uniprotkb:Ligand of Numb-protein X 1(gene name synonym)|uniprotkb:PDZ domain-containing RING finger protein 2(gene name synonym)|uniprotkb:PDZRN2(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase LNX(gene name synonym)|uniprotkb:UNQ574/PRO1136(orf name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552936|imex:IM-24995-3805	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009980.1|sgd:S000000647|interpro:IPR002110(Ankyrin)|interpro:IPR036770|ensemblfungi:YCR051W(gene)|ensemblfungi:YCR051W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)	refseq:NP_001119800.1|refseq:NP_116011.2|refseq:XP_005265842.1|refseq:XP_016864265.1|ensembl:ENSG00000072201(gene)|ensembl:ENST00000263925(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR036034|mint:Q8TBB1|rcsb pdb:3B76|rcsb pdb:5H7R|rcsb pdb:5H7S|reactome:R-HSA-983168	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:xSvXYNOUhBZjJgwGzwJ+muPq8tU559292	rogid:tWvePnVxh9yxWl8nQd3KZhCSKKo9606	intact-crc:74FD0CBD59A483A3|rigid:/Yna5fluuFNb50rujtP1z/VIRlM	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8TBB1	uniprotkb:P22803	intact:EBI-739832|uniprotkb:Q4W5K7|uniprotkb:Q8N4C2|uniprotkb:Q96MJ7|uniprotkb:Q9BY20|ensembl:ENSP00000263925	intact:EBI-19598|uniprotkb:D6VUZ2|ensemblfungi:YGR209C	psi-mi:lnx1_human(display_long)|uniprotkb:LNX1(gene name)|psi-mi:LNX1(display_short)|uniprotkb:LNX(gene name synonym)|uniprotkb:Numb-binding protein 1(gene name synonym)|uniprotkb:Ligand of Numb-protein X 1(gene name synonym)|uniprotkb:PDZ domain-containing RING finger protein 2(gene name synonym)|uniprotkb:PDZRN2(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase LNX(gene name synonym)|uniprotkb:UNQ574/PRO1136(orf name)	psi-mi:trx2_yeast(display_long)|uniprotkb:TRX2(gene name)|psi-mi:TRX2(display_short)|uniprotkb:TRX1(gene name synonym)|uniprotkb:G7746(orf name)|uniprotkb:YGR209C(locus name)|uniprotkb:Thioredoxin II(gene name synonym)|uniprotkb:Thioredoxin-1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552932|imex:IM-24995-3804	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001119800.1|refseq:NP_116011.2|refseq:XP_005265842.1|refseq:XP_016864265.1|ensembl:ENSG00000072201(gene)|ensembl:ENST00000263925(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR036034|mint:Q8TBB1|rcsb pdb:3B76|rcsb pdb:5H7R|rcsb pdb:5H7S|reactome:R-HSA-983168	sgd:S000003441|go:"GO:0009263"(deoxyribonucleotide biosynthetic process)|go:"GO:0015031"(protein transport)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0015036"(disulfide oxidoreductase activity)|go:"GO:0042144"(vacuole fusion, non-autophagic)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0080058"(protein deglutathionylation)|interpro:IPR005746(Thioredoxin)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017937|interpro:IPR036249|rcsb pdb:2FA4|rcsb pdb:2HSY|rcsb pdb:3PIN|rcsb pdb:4DSS|rcsb pdb:7BVV|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|ensemblfungi:YGR209C(gene)|ensemblfungi:YGR209C_mRNA(transcript)|go:"GO:0000011"(vacuole inheritance)|go:"GO:0000103"(sulfate assimilation)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006662"(glycerol ether metabolic process)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|refseq:NP_011725.3|dip:DIP-5552N|mint:P22803	-	-	crc64:071503762C90D451	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:tWvePnVxh9yxWl8nQd3KZhCSKKo9606	rogid:pRt9fGROPXW+o4g6ynOmCDiclFk559292	intact-crc:E15F5A0D8B18CB77|rigid:MqEiw6U/WmcKG7kZPaq/vJFAgWQ	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q12245	uniprotkb:Q8TAP6	intact:EBI-2343020|uniprotkb:D6W3M5|uniprotkb:Q6Q5F7|ensemblfungi:YPL144W	intact:EBI-742887|ensembl:ENSP00000262127|uniprotkb:Q658N5|uniprotkb:Q9H9U7|uniprotkb:B0YJB2|uniprotkb:B4DXG5|uniprotkb:B4DZW1	psi-mi:poc4_yeast(display_long)|uniprotkb:POC4(gene name)|psi-mi:POC4(display_short)|uniprotkb:YPL144W(locus name)|uniprotkb:DMP1(gene name synonym)	psi-mi:cep76_human(display_long)|uniprotkb:CEP76(gene name)|psi-mi:CEP76(display_short)|uniprotkb:C18orf9(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552916|imex:IM-24995-3800	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015181.1|sgd:S000006065|dip:DIP-8930N|mint:Q12245|ensemblfungi:YPL144W(gene)|ensemblfungi:YPL144W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043248"(proteasome assembly)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|interpro:IPR018854|rcsb pdb:2Z5B|rcsb pdb:2Z5C	refseq:NP_079175.2|ensembl:ENSG00000101624(gene)|ensembl:ENST00000262127(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0046599"(regulation of centriole replication)|interpro:IPR028926|interpro:IPR038765|mint:Q8TAP6|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_001258918.1	-	crc64:1CC7C6074CF4AC08	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:IT8/s4OOCv/pZK9VkZJ5J8ye438559292	rogid:fWzb8oIU35oVWomyDrf8u5sbxUk9606	intact-crc:0470C3517E35C995|rigid:a56IIFxvfAseknEUcfwhRs6fS6c	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q04307	uniprotkb:Q8TAP6	intact:EBI-15858|uniprotkb:Q2VQW5|ensemblfungi:YDR045C|uniprotkb:D6VS33	intact:EBI-742887|ensembl:ENSP00000262127|uniprotkb:Q658N5|uniprotkb:Q9H9U7|uniprotkb:B0YJB2|uniprotkb:B4DXG5|uniprotkb:B4DZW1	psi-mi:rpc10_yeast(display_long)|uniprotkb:RPC11(gene name)|psi-mi:RPC11(display_short)|uniprotkb:YDR045C(locus name)|uniprotkb:YD9609.01C(orf name)|uniprotkb:RNA polymerase III subunit C11(gene name synonym)|uniprotkb:DNA-directed RNA polymerases III 12.5 kDa polypeptide(gene name synonym)	psi-mi:cep76_human(display_long)|uniprotkb:CEP76(gene name)|psi-mi:CEP76(display_short)|uniprotkb:C18orf9(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552924|imex:IM-24995-3802	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YDR045C(gene)|refseq:NP_010330.1|sgd:S000002452|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006386"(termination of RNA polymerase III transcription)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042779"(tRNA 3'-trailer cleavage)|go:"GO:0042797"(tRNA transcription by RNA polymerase III)|interpro:IPR001222(Zinc finger, TFIIS-type)|interpro:IPR001529(DNA-directed RNA polymerase, M/15 kDa subunit)|interpro:IPR012164(DNA-directed RNA polymerase, subunit C11/M/9)|interpro:IPR019761|interpro:IPR034014|rcsb pdb:3QT1|ensemblfungi:YDR045C_mRNA(transcript)|rcsb pdb:5FJ8|rcsb pdb:5FJ9|rcsb pdb:5FJA|rcsb pdb:6CNB|rcsb pdb:6CNC|rcsb pdb:6CND|rcsb pdb:6CNF|rcsb pdb:6EU0|rcsb pdb:6EU2|rcsb pdb:6EU3|rcsb pdb:6F40|rcsb pdb:6F41|rcsb pdb:6F42|rcsb pdb:6F44|rcsb pdb:6TUT|reactome:R-SCE-76061|reactome:R-SCE-76066|rcsb pdb:6EU1|dip:DIP-887N|mint:Q04307	refseq:NP_079175.2|ensembl:ENSG00000101624(gene)|ensembl:ENST00000262127(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0046599"(regulation of centriole replication)|interpro:IPR028926|interpro:IPR038765|mint:Q8TAP6|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_001258918.1	-	crc64:E4AA802EC9F92230	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:G2fIQbptabHIUI224iPtTJF+dIs559292	rogid:fWzb8oIU35oVWomyDrf8u5sbxUk9606	intact-crc:6AE89AA4A6F5F00F|rigid:weMc+1uTiK5j8BMXnQgGYI5a/DA	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q04978	uniprotkb:Q8TAP6	intact:EBI-27823|uniprotkb:D6VZC2|ensemblfungi:YML053C	intact:EBI-742887|ensembl:ENSP00000262127|uniprotkb:Q658N5|uniprotkb:Q9H9U7|uniprotkb:B0YJB2|uniprotkb:B4DXG5|uniprotkb:B4DZW1	psi-mi:ymf3_yeast(display_long)|uniprotkb:YM9958.09C(orf name)|uniprotkb:YML053C(locus name)	psi-mi:cep76_human(display_long)|uniprotkb:CEP76(gene name)|psi-mi:CEP76(display_short)|uniprotkb:C18orf9(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552920|imex:IM-24995-3801	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000004517|refseq:NP_013659.1|dip:DIP-1950N|ensemblfungi:YML053C(gene)|ensemblfungi:YML053C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)	refseq:NP_079175.2|ensembl:ENSG00000101624(gene)|ensembl:ENST00000262127(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0046599"(regulation of centriole replication)|interpro:IPR028926|interpro:IPR038765|mint:Q8TAP6|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_001258918.1	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:eYvLCLQP+e6HSEiAjDeWkJBUCTU559292	rogid:fWzb8oIU35oVWomyDrf8u5sbxUk9606	intact-crc:4E53D08E5F1C790B|rigid:Q71mEizYAeqEhHQP4PwKyLKNgpc	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P46948	uniprotkb:Q8TAP6	intact:EBI-1788|uniprotkb:D6VUX7|ensemblfungi:YGR195W	intact:EBI-742887|ensembl:ENSP00000262127|uniprotkb:Q658N5|uniprotkb:Q9H9U7|uniprotkb:B0YJB2|uniprotkb:B4DXG5|uniprotkb:B4DZW1	psi-mi:rrp41_yeast(display_long)|uniprotkb:SKI6(gene name)|psi-mi:SKI6(display_short)|uniprotkb:YGR195W(locus name)|uniprotkb:G7587(orf name)|uniprotkb:ECM20(gene name synonym)|uniprotkb:Ribosomal RNA-processing protein 41(gene name synonym)|uniprotkb:Superkiller protein 6(gene name synonym)|uniprotkb:Extracellular mutant protein 20(gene name synonym)|uniprotkb:RRP41(gene name synonym)	psi-mi:cep76_human(display_long)|uniprotkb:CEP76(gene name)|psi-mi:CEP76(display_short)|uniprotkb:C18orf9(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552928|imex:IM-24995-3803	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003427|refseq:NP_011711.3|dip:DIP-2083N|mint:P46948|ensemblfungi:YGR195W(gene)|ensemblfungi:YGR195W_mRNA(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034473"(U1 snRNA 3'-end processing)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0034476"(U5 snRNA 3'-end processing)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071039"(nuclear polyadenylation-dependent CUT catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345|rcsb pdb:2WP8|rcsb pdb:4IFD|rcsb pdb:4OO1|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5G06|rcsb pdb:5JEA|rcsb pdb:5K36|rcsb pdb:5OKZ|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-429958|reactome:R-SCE-450385|reactome:R-SCE-450513|reactome:R-SCE-6791226	refseq:NP_079175.2|ensembl:ENSG00000101624(gene)|ensembl:ENST00000262127(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0046599"(regulation of centriole replication)|interpro:IPR028926|interpro:IPR038765|mint:Q8TAP6|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_001258918.1	-	crc64:C80EFFB528A43044	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:I7vEo0EUB1jZO+3v12H0LwVbgmo559292	rogid:fWzb8oIU35oVWomyDrf8u5sbxUk9606	intact-crc:421F676C7680E769|rigid:5TWeomSSqBF09jLn+neEbi3/SeA	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8TGM2	uniprotkb:Q15654	intact:EBI-11537624|ensemblfungi:YLR347W-A	intact:EBI-742327|uniprotkb:O15170|uniprotkb:O15275|uniprotkb:Q9BTB2|uniprotkb:Q9BUE5|uniprotkb:Q9BXP3|uniprotkb:Q9UNT4|uniprotkb:A4D2E7|ensembl:ENSP00000200457|uniprotkb:F2ZC07|uniprotkb:F2ZC08	psi-mi:yl347_yeast(display_long)|uniprotkb:YLR347W-A(locus name)	psi-mi:trip6_human(display_long)|uniprotkb:TRIP6(gene name)|psi-mi:TRIP6(display_short)|uniprotkb:OIP1(gene name synonym)|uniprotkb:Opa-interacting protein 1(gene name synonym)|uniprotkb:Zyxin-related protein 1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552952|imex:IM-24995-3809	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000028681|ensemblfungi:YLR347W-A(gene)|ensemblfungi:YLR347W-A_mRNA(transcript)	refseq:NP_003293.2|ensembl:ENSP00000200457|ensembl:ENST00000417475|ensembl:ENSP00000413817|ensembl:ENST00000437505|ensembl:ENSP00000410736|ensembl:ENST00000619988|ensembl:ENSP00000479865|ensembl:ENSG00000087077(gene)|ensembl:ENST00000200457(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003723"(RNA binding)|go:"GO:0005149"(interleukin-1 receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0019900"(kinase binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0043009"(chordate embryonic development)|go:"GO:0046872"(metal ion binding)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|interpro:IPR001781(Zinc finger, LIM-type)|mint:Q15654|rcsb pdb:1X61|rcsb pdb:2DLO|dip:DIP-34466N	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/03/16	rogid:eZ3330guTyvylD3kiCyArvlGWGI559292	rogid:9Okf3b6sMMwX5awAx991GN9iSsQ9606	intact-crc:C0BAF3EEB0B70A15|rigid:j9x6kqXpb1RT8oOpj+apAitcB6I	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q06819	uniprotkb:Q8TBB1	intact:EBI-166|ensemblfungi:YPR082C|uniprotkb:D6W484	intact:EBI-739832|uniprotkb:Q4W5K7|uniprotkb:Q8N4C2|uniprotkb:Q96MJ7|uniprotkb:Q9BY20|ensembl:ENSP00000263925	psi-mi:dib1_yeast(display_long)|uniprotkb:DIB1(gene name)|psi-mi:DIB1(display_short)|uniprotkb:CDH1(gene name synonym)|uniprotkb:SNU16(gene name synonym)|uniprotkb:YPR082C(locus name)|uniprotkb:P9513.12(orf name)	psi-mi:lnx1_human(display_long)|uniprotkb:LNX1(gene name)|psi-mi:LNX1(display_short)|uniprotkb:LNX(gene name synonym)|uniprotkb:Numb-binding protein 1(gene name synonym)|uniprotkb:Ligand of Numb-protein X 1(gene name synonym)|uniprotkb:PDZ domain-containing RING finger protein 2(gene name synonym)|uniprotkb:PDZRN2(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase LNX(gene name synonym)|uniprotkb:UNQ574/PRO1136(orf name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552940|imex:IM-24995-3806	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015407.1|sgd:S000006286|ensemblfungi:YPR082C(gene)|ensemblfungi:YPR082C_mRNA(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005682"(U5 snRNP)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|interpro:IPR004123(mRNA splicing factor, thioredoxin-like U5 snRNP)|interpro:IPR036249|rcsb pdb:3JCM|rcsb pdb:5GAN|rcsb pdb:5GAP|rcsb pdb:5NRL|rcsb pdb:5ZWM|rcsb pdb:5ZWO|dip:DIP-1289N	refseq:NP_001119800.1|refseq:NP_116011.2|refseq:XP_005265842.1|refseq:XP_016864265.1|ensembl:ENSG00000072201(gene)|ensembl:ENST00000263925(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR036034|mint:Q8TBB1|rcsb pdb:3B76|rcsb pdb:5H7R|rcsb pdb:5H7S|reactome:R-HSA-983168	-	crc64:B8C11278571C57E5	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:mRibIpinKPlRNdh60VJj/Z0tjUc559292	rogid:tWvePnVxh9yxWl8nQd3KZhCSKKo9606	intact-crc:9CC85AE92F59B79B|rigid:Z62+WYYqaD8KbDFQTEubq/DK/Pg	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O14468	uniprotkb:Q8TC20-4	intact:EBI-2343965|uniprotkb:D6W304|ensemblfungi:YOR304C-A	intact:EBI-11522698|ensembl:ENSP00000390644	psi-mi:yo304_yeast(display_long)|uniprotkb:YOR304C-A(locus name)	psi-mi:q8tc20-4(display_long)|uniprotkb:CTAG3(gene name synonym)|uniprotkb:Cancer/testis antigen 3(gene name synonym)|uniprotkb:CAGE1(gene name)|psi-mi:CAGE1(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552944|imex:IM-24995-3807	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005830|refseq:NP_014949.3|mint:O14468|ensemblfungi:YOR304C-A(gene)|ensemblfungi:YOR304C-A_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005933"(cellular bud)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0043332"(mating projection tip)|go:"GO:0051017"(actin filament bundle assembly)	intact:EBI-10196469(isoform-parent)|ensembl:ENSG00000164304(gene)|ensembl:ENST00000458291(transcript)|uniprotkb:Q8TC20-4(isoform-parent)	-	-	isoform-comment:No experimental confirmation available. May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:+5KU/P9FeqlhSbGhpYJ1V6DqQNg559292	rogid:rbycl1bawuMuBA8D5NfrekzCADM9606	intact-crc:B06B6CDD1E2CADDD|rigid:m8EFDhKq0op7IB8ISGsuBL8uk4s	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P40454	uniprotkb:Q8TC20-4	intact:EBI-25278|uniprotkb:D6VVD4|ensemblfungi:YIL153W	intact:EBI-11522698|ensembl:ENSP00000390644	psi-mi:ptpa1_yeast(display_long)|uniprotkb:YIL153W(locus name)|uniprotkb:RRD1(gene name)|psi-mi:RRD1(display_short)|uniprotkb:NCS1(gene name synonym)|uniprotkb:YPA1(gene name synonym)|uniprotkb:Peptidyl-prolyl cis-trans isomerase PTPA-1(gene name synonym)|uniprotkb:Phosphotyrosyl phosphatase activator 1(gene name synonym)	psi-mi:q8tc20-4(display_long)|uniprotkb:CTAG3(gene name synonym)|uniprotkb:Cancer/testis antigen 3(gene name synonym)|uniprotkb:CAGE1(gene name)|psi-mi:CAGE1(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552948|imex:IM-24995-3808	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012113.1|sgd:S000001415|mint:P40454|dip:DIP-5663N|ensemblfungi:YIL153W(gene)|ensemblfungi:YIL153W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006914"(autophagy)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008160"(protein tyrosine phosphatase activator activity)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0043618"(regulation of transcription from RNA polymerase II promoter in response to stress)|interpro:IPR004327(Phosphotyrosyl phosphatase activator, PTPA)|interpro:IPR037218|interpro:IPR043170|rcsb pdb:2IXO|rcsb pdb:2IXP	intact:EBI-10196469(isoform-parent)|ensembl:ENSG00000164304(gene)|ensembl:ENST00000458291(transcript)|uniprotkb:Q8TC20-4(isoform-parent)	-	-	isoform-comment:No experimental confirmation available. May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:It2q8WlpmvLEZ1fqpRF5Fypw9Q4559292	rogid:rbycl1bawuMuBA8D5NfrekzCADM9606	intact-crc:5C2ACF92BD0C3D34|rigid:13PoisQfPDKOkC2l9hFj6Oh7Dzw	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8WTR7	uniprotkb:Q12161	intact:EBI-751409|uniprotkb:Q9ULS9|uniprotkb:Q9Y4Q7|uniprotkb:A8K8T7|intact:EBI-28978826|ensembl:ENSP00000270617|ensembl:ENSP00000375697|ensembl:ENSP00000472808	intact:EBI-34372|uniprotkb:D6W213|ensemblfungi:YOL054W	psi-mi:zn473_human(display_long)|uniprotkb:Zinc finger protein 100 homolog(gene name synonym)|uniprotkb:ZNF473(gene name)|psi-mi:ZNF473(display_short)|uniprotkb:KIAA1141(gene name synonym)|uniprotkb:ZFP100(gene name synonym)	psi-mi:psh1_yeast(display_long)|uniprotkb:PSH1(gene name)|psi-mi:PSH1(display_short)|uniprotkb:POB3/SPT16 histone-associated protein 1(gene name synonym)|uniprotkb:O1263(orf name)|uniprotkb:YOL054W(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552972|imex:IM-24995-3814	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001006657.1|refseq:NP_056243.1|ensembl:ENSP00000270617|ensembl:ENSP00000375697|ensembl:ENSP00000472808|refseq:NP_001295353.1|ensembl:ENSG00000142528(gene)|ensembl:ENST00000270617(transcript)|ensembl:ENST00000391821(transcript)|ensembl:ENST00000595661(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006398"(mRNA 3'-end processing by stem-loop binding and cleavage)|go:"GO:0015030"(Cajal body)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|rcsb pdb:2EMB|rcsb pdb:2EMC|rcsb pdb:2EME|rcsb pdb:2EOU|rcsb pdb:2EOX|rcsb pdb:2EOY|rcsb pdb:2EOZ|rcsb pdb:2YRH|rcsb pdb:2YRJ|rcsb pdb:2YSV|rcsb pdb:2YTD|rcsb pdb:2YTE|rcsb pdb:2YTT|rcsb pdb:2YU5|reactome:R-HSA-111367|reactome:R-HSA-212436|reactome:R-HSA-73856|reactome:R-HSA-77588	refseq:NP_014587.1|sgd:S000005415|mint:Q12161|dip:DIP-6481N|ensemblfungi:YOL054W(gene)|ensemblfungi:YOL054W_mRNA(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907	-	-	crc64:CE0ECBCB6D465554	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Tm+mqhJ8JVqLYFprsek+VYhcnOI9606	rogid:AvPMRd/GjfaTyQjEfMPhBVcvOs4559292	intact-crc:E1EC32624DF07018|rigid:9TdmBK0UL0UE5I8qwhuByTvAazU	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8TGQ7	uniprotkb:Q12846	intact:EBI-2343396|uniprotkb:D6W4G0|ensemblfungi:YPR159C-A	intact:EBI-744942|uniprotkb:Q15525|ensembl:ENSP00000317714|uniprotkb:Q6FHE8|uniprotkb:A8MXY0	psi-mi:yp159_yeast(display_long)|uniprotkb:YPR159C-A(locus name)	psi-mi:stx4_human(display_long)|uniprotkb:Renal carcinoma antigen NY-REN-31(gene name synonym)|uniprotkb:STX4(gene name)|psi-mi:STX4(display_short)|uniprotkb:STX4A(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552968|imex:IM-24995-3813	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000028725|refseq:NP_878184.1|ensemblfungi:YPR159C-A(gene)|ensemblfungi:YPR159C-A_mRNA(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0016021"(integral component of membrane)	ensembl:ENSG00000103496(gene)|refseq:NP_004595.2|ensembl:ENST00000313843(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0000322"(storage vacuole)|go:"GO:0002639"(positive regulation of immunoglobulin production)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005768"(endosome)|go:"GO:0005773"(vacuole)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006887"(exocytosis)|go:"GO:0006906"(vesicle fusion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016230"(sphingomyelin phosphodiesterase activator activity)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0032589"(neuron projection membrane)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035493"(SNARE complex assembly)|go:"GO:0035749"(myelin sheath adaxonal region)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0036477"(somatodendritic compartment)|go:"GO:0042581"(specific granule)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043197"(dendritic spine)|go:"GO:0043219"(lateral loop)|go:"GO:0043311"(positive regulation of eosinophil degranulation)|go:"GO:0045202"(synapse)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0048278"(vesicle docking)|go:"GO:0048284"(organelle fusion)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048787"(presynaptic active zone membrane)|go:"GO:0050921"(positive regulation of chemotaxis)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1902041"(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1903575"(cornified envelope assembly)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|reactome:R-HSA-114516|reactome:R-HSA-1236974|reactome:R-HSA-1445148|reactome:R-HSA-199992|reactome:R-HSA-449836|interpro:IPR006011(Syntaxin, N-terminal)|refseq:NP_001259025.1	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:QGsci3FKQweBQvaMDdLKyHdq8tM559292	rogid:NvOLGIGe/XO2aDPSpdPzrtKniZY9606	intact-crc:497591CF30533F77|rigid:SJ4vQ3B3xUYzq+sCfQ4y92YU6Rk	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8N9N5-2	uniprotkb:Q8TGM2	intact:EBI-11524452|ensembl:ENSP00000347125	intact:EBI-11537624|ensemblfungi:YLR347W-A	psi-mi:q8n9n5-2(display_long)|uniprotkb:BANP(gene name)|psi-mi:BANP(display_short)|uniprotkb:BEN domain-containing protein 1(gene name synonym)|uniprotkb:BEND1(gene name synonym)|uniprotkb:Btg3-associated nuclear protein(gene name synonym)|uniprotkb:SMAR1(gene name synonym)|uniprotkb:Scaffold/matrix-associated region-1-binding protein(gene name synonym)	psi-mi:yl347_yeast(display_long)|uniprotkb:YLR347W-A(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552956|imex:IM-24995-3810	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000172530(gene)|ensembl:ENST00000355022(transcript)|intact:EBI-744695(isoform-parent)|uniprotkb:Q8N9N5-2(isoform-parent)	sgd:S000028681|ensemblfungi:YLR347W-A(gene)|ensemblfungi:YLR347W-A_mRNA(transcript)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/03/16	rogid:ESe6iCAhvq+i57fQHz3rGyg6UOo9606	rogid:eZ3330guTyvylD3kiCyArvlGWGI559292	intact-crc:0418C6DC9796AB20|rigid:I04O0BHD1/XyGh9QCQ1E7JgUl5o	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
intact:EBI-11524292	uniprotkb:Q8TGM2	-	intact:EBI-11537624|ensemblfungi:YLR347W-A	psi-mi:trip6(display_short)|psi-mi:EBI-11524292(display_long)	psi-mi:yl347_yeast(display_long)|uniprotkb:YLR347W-A(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552960|imex:IM-24995-3811	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	-	sgd:S000028681|ensemblfungi:YLR347W-A(gene)|ensemblfungi:YLR347W-A_mRNA(transcript)	-	no-uniprot-update:	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/03/16	rogid:S6W5lkNauGhNejln9bTVoqZjNL49606	rogid:eZ3330guTyvylD3kiCyArvlGWGI559292	intact-crc:F3E1414C7A27DFA2|rigid:zt6zAW9KVan93EIdtiZ7tge+kes	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8TGQ7	uniprotkb:Q8N6L0	intact:EBI-2343396|uniprotkb:D6W4G0|ensemblfungi:YPR159C-A	intact:EBI-749265|uniprotkb:Q96MC3|ensembl:ENSP00000404220	psi-mi:yp159_yeast(display_long)|uniprotkb:YPR159C-A(locus name)	psi-mi:kash5_human(display_long)|uniprotkb:KASH5(gene name)|psi-mi:KASH5(display_short)|uniprotkb:CCDC155(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 155(gene name synonym)|uniprotkb:KASH domain-containing protein 5(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552964|imex:IM-24995-3812	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000028725|refseq:NP_878184.1|ensemblfungi:YPR159C-A(gene)|ensemblfungi:YPR159C-A_mRNA(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0016021"(integral component of membrane)	refseq:NP_653289.3|ensembl:ENSG00000161609(gene)|ensembl:ENST00000447857(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034397"(telomere localization)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051225"(spindle assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0090172"(microtubule cytoskeleton organization involved in homologous chromosome segregation)|go:"GO:0090220"(chromosome localization to nuclear envelope involved in homologous chromosome segregation)|go:"GO:0090619"(meiotic spindle pole)|interpro:IPR011992(EF-Hand type)|interpro:IPR028168|interpro:IPR028170|interpro:IPR039508|mint:Q8N6L0|rcsb pdb:6R2I|rcsb pdb:6WMF	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:QGsci3FKQweBQvaMDdLKyHdq8tM559292	rogid:Wl9L7AcvDHCZuKjYLn8QgGIbZTc9606	intact-crc:35F95178B51A4282|rigid:H0Zg9HThbB8YZRiGY2k7psd6gUs	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P40507	uniprotkb:Q8WV44	intact:EBI-25083|uniprotkb:D6VVK5|ensemblfungi:YIL079C	intact:EBI-725997|uniprotkb:Q5BKT0|uniprotkb:Q7L484|uniprotkb:Q96Q10|intact:EBI-1551110|uniprotkb:Q9BSL8|uniprotkb:B3KNJ6|uniprotkb:D3DWR9|ensembl:ENSP00000320869	psi-mi:air1_yeast(display_long)|uniprotkb:Arginine methyltransferase-interacting RING finger protein 1(gene name synonym)|uniprotkb:AIR1(gene name)|psi-mi:AIR1(display_short)|uniprotkb:YIL079C(locus name)	psi-mi:tri41_human(display_long)|uniprotkb:TRIM41(gene name)|psi-mi:TRIM41(display_short)|uniprotkb:RINCK(gene name synonym)|uniprotkb:Tripartite motif-containing protein 41(gene name synonym)|uniprotkb:RING finger-interacting protein with C kinase(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM41(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552996|imex:IM-24995-3820	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012186.1|sgd:S000001341|mint:P40507|dip:DIP-2700N|ensemblfungi:YIL079C(gene)|ensemblfungi:YIL079C_mRNA(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031499"(TRAMP complex)|go:"GO:0043629"(ncRNA polyadenylation)|go:"GO:0071031"(nuclear mRNA surveillance of mRNA 3'-end processing)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071036"(nuclear polyadenylation-dependent snoRNA catabolic process)|go:"GO:0071037"(nuclear polyadenylation-dependent snRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071039"(nuclear polyadenylation-dependent CUT catabolic process)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR016713("Poly(A) polymerase complex, Air1/2")|interpro:IPR036875	refseq:NP_291027.3|refseq:NP_963921.1|ensembl:ENSG00000146063(gene)|ensembl:ENST00000315073(transcript)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0042802"(identical protein binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071225"(cellular response to muramyl dipeptide)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR042828|interpro:IPR043136|mint:Q8WV44|rcsb pdb:2EGM|reactome:R-HSA-983168	-	crc64:3CA920FA1204EC9C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:myPxXwP+mJgvoh50PLYk2Q3GMh4559292	rogid:BVqf0OHXPGsYe8F66mHzvD4XQ549606	intact-crc:085E693706D64560|rigid:Yz4r4Nxyaosre+oy+CJRJxVqaRc	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8WV44	uniprotkb:Q12259	intact:EBI-725997|uniprotkb:Q5BKT0|uniprotkb:Q7L484|uniprotkb:Q96Q10|intact:EBI-1551110|uniprotkb:Q9BSL8|uniprotkb:B3KNJ6|uniprotkb:D3DWR9|ensembl:ENSP00000320869	intact:EBI-30776|uniprotkb:D6VYA8|ensemblfungi:YLR108C	psi-mi:tri41_human(display_long)|uniprotkb:TRIM41(gene name)|psi-mi:TRIM41(display_short)|uniprotkb:RINCK(gene name synonym)|uniprotkb:Tripartite motif-containing protein 41(gene name synonym)|uniprotkb:RING finger-interacting protein with C kinase(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM41(gene name synonym)	psi-mi:yl108_yeast(display_long)|uniprotkb:L2913(orf name)|uniprotkb:YLR108C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552992|imex:IM-24995-3819	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_291027.3|refseq:NP_963921.1|ensembl:ENSG00000146063(gene)|ensembl:ENST00000315073(transcript)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0042802"(identical protein binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071225"(cellular response to muramyl dipeptide)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR042828|interpro:IPR043136|mint:Q8WV44|rcsb pdb:2EGM|reactome:R-HSA-983168	refseq:NP_013209.1|sgd:S000004098|dip:DIP-4075N|ensemblfungi:YLR108C(gene)|ensemblfungi:YLR108C_mRNA(transcript)|go:"GO:0005634"(nucleus)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:BVqf0OHXPGsYe8F66mHzvD4XQ549606	rogid:CzknxXhhvgMp3J0/oi197EgZ05U559292	intact-crc:0A9CF4483785E920|rigid:/RwvnIwtpDT3qyFJmHFHGzE5acQ	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P40507	uniprotkb:Q8WTR7	intact:EBI-25083|uniprotkb:D6VVK5|ensemblfungi:YIL079C	intact:EBI-751409|uniprotkb:Q9ULS9|uniprotkb:Q9Y4Q7|uniprotkb:A8K8T7|intact:EBI-28978826|ensembl:ENSP00000270617|ensembl:ENSP00000375697|ensembl:ENSP00000472808	psi-mi:air1_yeast(display_long)|uniprotkb:Arginine methyltransferase-interacting RING finger protein 1(gene name synonym)|uniprotkb:AIR1(gene name)|psi-mi:AIR1(display_short)|uniprotkb:YIL079C(locus name)	psi-mi:zn473_human(display_long)|uniprotkb:Zinc finger protein 100 homolog(gene name synonym)|uniprotkb:ZNF473(gene name)|psi-mi:ZNF473(display_short)|uniprotkb:KIAA1141(gene name synonym)|uniprotkb:ZFP100(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552976|imex:IM-24995-3815	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012186.1|sgd:S000001341|mint:P40507|dip:DIP-2700N|ensemblfungi:YIL079C(gene)|ensemblfungi:YIL079C_mRNA(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031499"(TRAMP complex)|go:"GO:0043629"(ncRNA polyadenylation)|go:"GO:0071031"(nuclear mRNA surveillance of mRNA 3'-end processing)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071036"(nuclear polyadenylation-dependent snoRNA catabolic process)|go:"GO:0071037"(nuclear polyadenylation-dependent snRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071039"(nuclear polyadenylation-dependent CUT catabolic process)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR016713("Poly(A) polymerase complex, Air1/2")|interpro:IPR036875	refseq:NP_001006657.1|refseq:NP_056243.1|ensembl:ENSP00000270617|ensembl:ENSP00000375697|ensembl:ENSP00000472808|refseq:NP_001295353.1|ensembl:ENSG00000142528(gene)|ensembl:ENST00000270617(transcript)|ensembl:ENST00000391821(transcript)|ensembl:ENST00000595661(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006398"(mRNA 3'-end processing by stem-loop binding and cleavage)|go:"GO:0015030"(Cajal body)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|rcsb pdb:2EMB|rcsb pdb:2EMC|rcsb pdb:2EME|rcsb pdb:2EOU|rcsb pdb:2EOX|rcsb pdb:2EOY|rcsb pdb:2EOZ|rcsb pdb:2YRH|rcsb pdb:2YRJ|rcsb pdb:2YSV|rcsb pdb:2YTD|rcsb pdb:2YTE|rcsb pdb:2YTT|rcsb pdb:2YU5|reactome:R-HSA-111367|reactome:R-HSA-212436|reactome:R-HSA-73856|reactome:R-HSA-77588	-	crc64:3CA920FA1204EC9C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:myPxXwP+mJgvoh50PLYk2Q3GMh4559292	rogid:Tm+mqhJ8JVqLYFprsek+VYhcnOI9606	intact-crc:2DCA74AE6AAD3870|rigid:mIzg72Yp2WZuS2yd/ygpPJ4s6Xg	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8WTU0	uniprotkb:P10507	intact:EBI-748248|uniprotkb:Q7Z4U6|uniprotkb:Q8WTS3|ensembl:ENSP00000302805	intact:EBI-11212|uniprotkb:D6VYG9|ensemblfungi:YLR163C	psi-mi:ddi1_human(display_long)|uniprotkb:DDI1(gene name)|psi-mi:DDI1(display_short)	psi-mi:mppb_yeast(display_long)|uniprotkb:MAS1(gene name)|psi-mi:MAS1(display_short)|uniprotkb:MIF1(gene name synonym)|uniprotkb:Beta-MPP(gene name synonym)|uniprotkb:Mitochondrial assembly protein 1(gene name synonym)|uniprotkb:Processing enhancing protein(gene name synonym)|uniprotkb:L9632.10(orf name)|uniprotkb:YLR163C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552984|imex:IM-24995-3817	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001001711.1|interpro:IPR000626(Ubiquitin)|interpro:IPR019103|interpro:IPR021109|interpro:IPR029071|interpro:IPR033882|rcsb pdb:3S8I|go:"GO:0097752"(regulation of DNA stability)|ensembl:ENSG00000170967(gene)|ensembl:ENST00000302259(transcript)|go:"GO:0004190"(aspartic-type endopeptidase activity)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0072711"(cellular response to hydroxyurea)|dip:DIP-60626N	rcsb pdb:1HR8|rcsb pdb:1HR9|reactome:R-SCE-611105|ensemblfungi:YLR163C_mRNA(transcript)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006627"(protein processing involved in protein targeting to mitochondrion)|go:"GO:0017087"(mitochondrial processing peptidase complex)|go:"GO:0046872"(metal ion binding)|interpro:IPR001431(Peptidase M16, zinc-binding site)|interpro:IPR007863(Peptidase M16, C-terminal)|interpro:IPR011249(Metalloenzyme, LuxS/M16 peptidase-like, metal-binding)|interpro:IPR011765(Peptidase M16, N-terminal)|rcsb pdb:1HR6|rcsb pdb:1HR7|ensemblfungi:YLR163C(gene)|refseq:NP_013264.1|sgd:S000004153|mint:P10507|dip:DIP-2402N	-	-	crc64:084CE63C495EDFC4	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:000xGRvL5rBRHv7/sbuzB7i7Wtc9606	rogid:VwOYuBlWEvXC631d5WAhOhjVAPc559292	intact-crc:681E46EB233C14F2|rigid:jpx1gdbg9ahPZ4bWDn5eNL6p70k	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P40087	uniprotkb:Q8WTU0	intact:EBI-5717|uniprotkb:D3DM50|ensemblfungi:YER143W	intact:EBI-748248|uniprotkb:Q7Z4U6|uniprotkb:Q8WTS3|ensembl:ENSP00000302805	psi-mi:ddi1_yeast(display_long)|uniprotkb:DDI1(gene name)|psi-mi:DDI1(display_short)|uniprotkb:v-SNARE-master 1(gene name synonym)|uniprotkb:VSM1(gene name synonym)|uniprotkb:YER143W(locus name)	psi-mi:ddi1_human(display_long)|uniprotkb:DDI1(gene name)|psi-mi:DDI1(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552980|imex:IM-24995-3816	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000000945|refseq:NP_011070.3|dip:DIP-1216N|mint:P40087|rcsb pdb:2MRP|rcsb pdb:2MWS|rcsb pdb:2N7E|rcsb pdb:4Z2Z|rcsb pdb:5KES|ensemblfungi:YER143W(gene)|ensemblfungi:YER143W_mRNA(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0004190"(aspartic-type endopeptidase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0009306"(protein secretion)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043328"(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0072710"(response to hydroxyurea)|go:"GO:1904855"(proteasome regulatory particle binding)|interpro:IPR001995(Peptidase A2A, retrovirus, catalytic)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR019103|interpro:IPR021109|interpro:IPR033882|rcsb pdb:2I1A|rcsb pdb:2MR9|rcsb pdb:2MRO	refseq:NP_001001711.1|interpro:IPR000626(Ubiquitin)|interpro:IPR019103|interpro:IPR021109|interpro:IPR029071|interpro:IPR033882|rcsb pdb:3S8I|go:"GO:0097752"(regulation of DNA stability)|ensembl:ENSG00000170967(gene)|ensembl:ENST00000302259(transcript)|go:"GO:0004190"(aspartic-type endopeptidase activity)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0072711"(cellular response to hydroxyurea)|dip:DIP-60626N	-	crc64:B43425B029B7658B	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:DHcLrKv/gQNKEXCievX6k6ikKL0559292	rogid:000xGRvL5rBRHv7/sbuzB7i7Wtc9606	intact-crc:EA6C3776A0DD78CC|rigid:wvG9/y0FG/QD7dqPs2aJuOh5m3I	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8WV44	uniprotkb:P53286	intact:EBI-725997|uniprotkb:Q5BKT0|uniprotkb:Q7L484|uniprotkb:Q96Q10|intact:EBI-1551110|uniprotkb:Q9BSL8|uniprotkb:B3KNJ6|uniprotkb:D3DWR9|ensembl:ENSP00000320869	intact:EBI-3796|uniprotkb:D6VUS2|ensemblfungi:YGR142W	psi-mi:tri41_human(display_long)|uniprotkb:TRIM41(gene name)|psi-mi:TRIM41(display_short)|uniprotkb:RINCK(gene name synonym)|uniprotkb:Tripartite motif-containing protein 41(gene name synonym)|uniprotkb:RING finger-interacting protein with C kinase(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM41(gene name synonym)	psi-mi:btn2_yeast(display_long)|uniprotkb:YGR142W(locus name)|uniprotkb:BTN2(gene name)|psi-mi:BTN2(display_short)|uniprotkb:Batten disease protein 2(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11552988|imex:IM-24995-3818	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_291027.3|refseq:NP_963921.1|ensembl:ENSG00000146063(gene)|ensembl:ENST00000315073(transcript)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0042802"(identical protein binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071225"(cellular response to muramyl dipeptide)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR042828|interpro:IPR043136|mint:Q8WV44|rcsb pdb:2EGM|reactome:R-HSA-983168	sgd:S000003374|refseq:NP_011658.3|dip:DIP-5534N|mint:P53286|ensemblfungi:YGR142W(gene)|ensemblfungi:YGR142W_mRNA(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005634"(nucleus)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006865"(amino acid transport)|go:"GO:0006885"(regulation of pH)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051087"(chaperone binding)|go:"GO:0140311"(protein sequestering activity)	-	-	crc64:E7AE1EB1E3612F3E	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:BVqf0OHXPGsYe8F66mHzvD4XQ549606	rogid:Cu27xkwGMNyS4zLvUaG1UeH2mE0559292	intact-crc:67151863C984A813|rigid:iONbbSGxSDbnGs+cYcaSNydYe7s	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P43556	uniprotkb:Q8WW24	intact:EBI-22845|uniprotkb:D6VTI3|ensemblfungi:YFL047W	intact:EBI-750487|ensembl:ENSP00000295201	psi-mi:rgd2_yeast(display_long)|uniprotkb:RGD2(gene name)|psi-mi:RGD2(display_short)|uniprotkb:YFL047W(locus name)	psi-mi:tekt4_human(display_long)|uniprotkb:TEKT4(gene name)|psi-mi:TEKT4(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553016|imex:IM-24995-3825	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_428268.1|sgd:S000001847|dip:DIP-4958N|mint:P43556|go:"GO:0005935"(cellular bud neck)|interpro:IPR031160|reactome:R-SCE-8856828|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0032153"(cell division site)|interpro:IPR000198(RhoGAP)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR027267|ensemblfungi:YFL047W(gene)|ensemblfungi:YFL047W_mRNA(transcript)|go:"GO:0000935"(division septum)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005934"(cellular bud tip)	refseq:NP_653306.1|ensembl:ENSG00000163060(gene)|ensembl:ENST00000295201(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0036126"(sperm flagellum)|go:"GO:0060271"(cilium assembly)|go:"GO:0060294"(cilium movement involved in cell motility)|interpro:IPR000435(Tektin)	-	crc64:52CF174C5F650157	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:TaphLAmYObi9RXMbE2tJDrHtVxA559292	rogid:uSPBMKPN9VTr6rsdxgUPpfWynIA9606	intact-crc:E61FA8E654346BD5|rigid:W5rR4lur6RJr3g69DaeB1n63rxQ	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q02821	uniprotkb:Q8WVF5	intact:EBI-1797|uniprotkb:D6W0Z8|ensemblfungi:YNL189W	intact:EBI-741463|ensembl:ENSP00000368402|uniprotkb:Q5W0P9	psi-mi:ima1_yeast(display_long)|uniprotkb:SRP1(gene name)|psi-mi:SRP1(display_short)|uniprotkb:KAP60(gene name synonym)|uniprotkb:YNL189W(locus name)|uniprotkb:N1606(orf name)|uniprotkb:Karyopherin subunit alpha(gene name synonym)|uniprotkb:Karyopherin-60(gene name synonym)|uniprotkb:Serine-rich RNA polymerase I suppressor protein(gene name synonym)	psi-mi:kctd4_human(display_long)|uniprotkb:KCTD4(gene name)|psi-mi:KCTD4(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553012|imex:IM-24995-3824	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014210.1|sgd:S000005133|dip:DIP-728N|mint:Q02821|ensemblfungi:YNL189W(gene)|ensemblfungi:YNL189W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0031144"(proteasome localization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042564"(NLS-dependent protein nuclear import complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|rcsb pdb:1BK5|rcsb pdb:1BK6|rcsb pdb:1EE4|rcsb pdb:1EE5|rcsb pdb:1UN0|rcsb pdb:1WA5|rcsb pdb:2C1T|rcsb pdb:4PVZ|rcsb pdb:4XZR|rcsb pdb:5H2W|rcsb pdb:5H2X|rcsb pdb:5T94	ensembl:ENSG00000180332(gene)|ensembl:ENST00000379108(transcript)|go:"GO:0051260"(protein homooligomerization)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR003131(Potassium channel, voltage dependent, Kv,  tetramerisation)|interpro:IPR011333(BTB/POZ fold)|refseq:NP_940686.2	-	crc64:8D3A0CB76F2E7C00	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:NyzC93xnBCb8DX/AH346lwg4u2A559292	rogid:03cd1lqmT8fReXzYqjrKSWUdqY89606	intact-crc:17C9ED55274889BC|rigid:6KdU4mjtwdu6qyVglZVNc05/CUs	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P47009	uniprotkb:Q8WV44	intact:EBI-3680883|uniprotkb:D6VW41|ensemblfungi:YJL144W	intact:EBI-725997|uniprotkb:Q5BKT0|uniprotkb:Q7L484|uniprotkb:Q96Q10|intact:EBI-1551110|uniprotkb:Q9BSL8|uniprotkb:B3KNJ6|uniprotkb:D3DWR9|ensembl:ENSP00000320869	psi-mi:yjo4_yeast(display_long)|uniprotkb:J0646(orf name)|uniprotkb:YJL144W(locus name)	psi-mi:tri41_human(display_long)|uniprotkb:TRIM41(gene name)|psi-mi:TRIM41(display_short)|uniprotkb:RINCK(gene name synonym)|uniprotkb:Tripartite motif-containing protein 41(gene name synonym)|uniprotkb:RING finger-interacting protein with C kinase(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM41(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553000|imex:IM-24995-3821	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	mint:P47009|sgd:S000003680|refseq:NP_012391.1|ensemblfungi:YJL144W(gene)|ensemblfungi:YJL144W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0042631"(cellular response to water deprivation)|go:"GO:0055106"(ubiquitin-protein transferase regulator activity)|go:"GO:0120174"(stress-induced homeostatically regulated protein degradation pathway)	refseq:NP_291027.3|refseq:NP_963921.1|ensembl:ENSG00000146063(gene)|ensembl:ENST00000315073(transcript)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0042802"(identical protein binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071225"(cellular response to muramyl dipeptide)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR042828|interpro:IPR043136|mint:Q8WV44|rcsb pdb:2EGM|reactome:R-HSA-983168	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:7kshIHHxzHSMcpP1vGF+sbEHkfA559292	rogid:BVqf0OHXPGsYe8F66mHzvD4XQ549606	intact-crc:C7027BE8F6552C3E|rigid:eN9UKvDnLfl7ng9xKtR6h2Aal4U	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P35182	uniprotkb:Q8WV92	intact:EBI-12784|uniprotkb:D6VRY2|ensemblfungi:YDL006W	intact:EBI-2691489|uniprotkb:Q69YV0|ensembl:ENSP00000289359	psi-mi:pp2c1_yeast(display_long)|uniprotkb:PTC1(gene name)|psi-mi:PTC1(display_short)|uniprotkb:TPD1(gene name synonym)|uniprotkb:YDL006W(locus name)|uniprotkb:D2925(orf name)	psi-mi:mitd1_human(display_long)|uniprotkb:MITD1(gene name)|psi-mi:MITD1(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553004|imex:IM-24995-3822	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR000222(Protein phosphatase 2C,  manganese/magnesium aspartate binding site)|interpro:IPR001932(Protein phosphatase 2C-related)|interpro:IPR015655(Protein phosphatase 2C)|interpro:IPR036457|ensemblfungi:YDL006W(gene)|ensemblfungi:YDL006W_mRNA(transcript)|go:"GO:0000001"(mitochondrion inheritance)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006388"(tRNA splicing, via endonucleolytic cleavage and ligation)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0046872"(metal ion binding)|go:"GO:0051389"(obsolete inactivation of MAPKK activity)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1990439"(MAP kinase serine/threonine phosphatase activity)|refseq:NP_010278.3|sgd:S000002164|mint:P35182|dip:DIP-1537N	refseq:NP_620153.1|refseq:NP_001307346.1|refseq:NP_001307347.1|refseq:NP_001307348.1|ensembl:ENSG00000158411(gene)|ensembl:ENST00000289359(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030496"(midbody)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0061952"(midbody abscission)|go:"GO:0070062"(extracellular exosome)|interpro:IPR007330(MIT)|interpro:IPR032341|interpro:IPR036181|interpro:IPR038113|rcsb pdb:2YMB|rcsb pdb:4A5X|rcsb pdb:4A5Z	-	crc64:FA384D2541B20D50	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:iWNdaik/M9S814zgZEQNyOktcX8559292	rogid:VY5MeLAmoWXB0gKSJR3d9OhT1Vk9606	intact-crc:793751AB7E6F53C7|rigid:knJUSs7YD4HeXZ2EhLi6hDFYgDI	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P38340	uniprotkb:Q8WVF5	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-741463|ensembl:ENSP00000368402|uniprotkb:Q5W0P9	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:kctd4_human(display_long)|uniprotkb:KCTD4(gene name)|psi-mi:KCTD4(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553008|imex:IM-24995-3823	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F	ensembl:ENSG00000180332(gene)|ensembl:ENST00000379108(transcript)|go:"GO:0051260"(protein homooligomerization)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR003131(Potassium channel, voltage dependent, Kv,  tetramerisation)|interpro:IPR011333(BTB/POZ fold)|refseq:NP_940686.2	-	crc64:66699F37B0013088	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:03cd1lqmT8fReXzYqjrKSWUdqY89606	intact-crc:985816A47683B73C|rigid:VEISpv+OQR1w87VcnwpVTRsUVoQ	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P28004	uniprotkb:Q8WWB3	intact:EBI-20640|uniprotkb:D6VPI6|ensemblfungi:YAL032C	intact:EBI-740680|ensembl:ENSP00000361276|ensembl:ENSP00000361278|ensembl:ENSP00000402890|uniprotkb:Q5QP03|uniprotkb:Q5QP04|uniprotkb:Q6WNP4|uniprotkb:Q6ZU87|uniprotkb:A8K927	psi-mi:prp45_yeast(display_long)|uniprotkb:YAL032C(locus name)|uniprotkb:PRP45(gene name)|psi-mi:PRP45(display_short)|uniprotkb:FUN20(gene name synonym)	psi-mi:dydc1_human(display_long)|uniprotkb:DYDC1(gene name)|psi-mi:DYDC1(display_short)|uniprotkb:DPY30D1(gene name synonym)|uniprotkb:RSD9(orf name)|uniprotkb:RSD-9(orf name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553040|imex:IM-24995-3831	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009370.1|sgd:S000000030|ensemblfungi:YAL032C(gene)|ensemblfungi:YAL032C_mRNA(transcript)|go:"GO:0000350"(generation of catalytic spliceosome for second transesterification step)|go:"GO:0005634"(nucleus)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|interpro:IPR004015(SKIP/SNW)|interpro:IPR017862|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|dip:DIP-2774N|mint:P28004	refseq:NP_620167.1|ensembl:ENSG00000170788(gene)|ensembl:ENST00000372202(transcript)|ensembl:ENST00000372204(transcript)|ensembl:ENST00000421924(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0006348"|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|interpro:IPR007858(Dpy-30)|interpro:IPR037856|refseq:XP_011537636.1|refseq:XP_011537637.1|refseq:NP_001255982.1|refseq:XP_005269606.1|refseq:XP_005269607.1	-	crc64:FE5A724186D7FE84	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:qoHF1UsO3k+JOTOfigSuy2P84/k559292	rogid:W6GUazYFXZGHGijUBpAJ5GiRuXA9606	intact-crc:04FE8CA94ADA7A6C|rigid:m+GJ+aeiVaLiiud/0VLVpK7jNIs	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P47041	uniprotkb:Q8WWB3	intact:EBI-25889|uniprotkb:D6VWC4|ensemblfungi:YJL058C	intact:EBI-740680|ensembl:ENSP00000361276|ensembl:ENSP00000361278|ensembl:ENSP00000402890|uniprotkb:Q5QP03|uniprotkb:Q5QP04|uniprotkb:Q6WNP4|uniprotkb:Q6ZU87|uniprotkb:A8K927	psi-mi:bit61_yeast(display_long)|uniprotkb:YJL058C(locus name)|uniprotkb:J1141(orf name)|uniprotkb:61 kDa binding partner of TOR2 protein(gene name synonym)|uniprotkb:BIT61(gene name)|psi-mi:BIT61(display_short)	psi-mi:dydc1_human(display_long)|uniprotkb:DYDC1(gene name)|psi-mi:DYDC1(display_short)|uniprotkb:DPY30D1(gene name synonym)|uniprotkb:RSD9(orf name)|uniprotkb:RSD-9(orf name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553036|imex:IM-24995-3830	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012477.1|sgd:S000003594|dip:DIP-1444N|reactome:R-SCE-1257604|reactome:R-SCE-389357|reactome:R-SCE-5218920|ensemblfungi:YJL058C(gene)|ensemblfungi:YJL058C_mRNA(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005737"(cytoplasm)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0031932"(TORC2 complex)|go:"GO:0038203"(TORC2 signaling)|go:"GO:0071944"(cell periphery)|interpro:IPR013745(HbrB-like)|reactome:R-SCE-6804757	refseq:NP_620167.1|ensembl:ENSG00000170788(gene)|ensembl:ENST00000372202(transcript)|ensembl:ENST00000372204(transcript)|ensembl:ENST00000421924(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0006348"|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|interpro:IPR007858(Dpy-30)|interpro:IPR037856|refseq:XP_011537636.1|refseq:XP_011537637.1|refseq:NP_001255982.1|refseq:XP_005269606.1|refseq:XP_005269607.1	-	crc64:99F0F96840311F4B	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:H+zcKwbWL90wsmvD9TfWYmEbRwM559292	rogid:W6GUazYFXZGHGijUBpAJ5GiRuXA9606	intact-crc:2E06E8A3A2F08FC2|rigid:jN/mk7rrsZJCN6xIQ7oIzgJAC2c	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8WW34-2	uniprotkb:P38340	intact:EBI-11528917|ensembl:ENSP00000369959	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:q8ww34-2(display_long)|uniprotkb:TMEM239(gene name)|psi-mi:TMEM239(display_short)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553020|imex:IM-24995-3826	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-9675724(isoform-parent)|uniprotkb:Q8WW34-2(isoform-parent)|ensembl:ENSG00000198326(gene)|ensembl:ENST00000380585(transcript)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F	-	isoform-comment:No experimental confirmation available.	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:1VqWIwPpWs6WjW8eDoJUHz2pegw9606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:70FEE2D6B45F1813|rigid:N6bd/BTl+wSDGwf83LA5bfD+5CM	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P38736	uniprotkb:Q8WW34-2	intact:EBI-24365|uniprotkb:D3DKT7|ensemblfungi:YHL031C	intact:EBI-11528917|ensembl:ENSP00000369959	psi-mi:gosr1_yeast(display_long)|uniprotkb:Golgi SNARE protein 1(gene name synonym)|uniprotkb:GOS1(gene name)|psi-mi:GOS1(display_short)|uniprotkb:Protein transport protein GOS1(gene name synonym)|uniprotkb:YHL031C(locus name)	psi-mi:q8ww34-2(display_long)|uniprotkb:TMEM239(gene name)|psi-mi:TMEM239(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553028|imex:IM-24995-3828	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011832.1|sgd:S000001023|reactome:R-SCE-6811438|dip:DIP-2490N|reactome:R-SCE-6807878|ensemblfungi:YHL031C(gene)|ensemblfungi:YHL031C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005797"(Golgi medial cisterna)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0048193"(Golgi vesicle transport)|go:"GO:0048209"(regulation of vesicle targeting, to, from or within Golgi)|interpro:IPR023601|go:"GO:0006906"(vesicle fusion)	intact:EBI-9675724(isoform-parent)|uniprotkb:Q8WW34-2(isoform-parent)|ensembl:ENSG00000198326(gene)|ensembl:ENST00000380585(transcript)	-	-	isoform-comment:No experimental confirmation available.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:pAzDzV46XXzIOB4p/oc1PlMc54E559292	rogid:1VqWIwPpWs6WjW8eDoJUHz2pegw9606	intact-crc:5A54237FCB5F32A5|rigid:JPdB/sKMG5ILWTWJY5RggSkGkzw	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8WW34-2	uniprotkb:P38815	intact:EBI-11528917|ensembl:ENSP00000369959	intact:EBI-24665|uniprotkb:D3DL55|ensemblfungi:YHR105W	psi-mi:q8ww34-2(display_long)|uniprotkb:TMEM239(gene name)|psi-mi:TMEM239(display_short)	psi-mi:ypt35_yeast(display_long)|uniprotkb:YHR105W(locus name)|uniprotkb:YPT35(gene name)|psi-mi:YPT35(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553024|imex:IM-24995-3827	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-9675724(isoform-parent)|uniprotkb:Q8WW34-2(isoform-parent)|ensembl:ENSG00000198326(gene)|ensembl:ENST00000380585(transcript)	refseq:NP_011973.1|sgd:S000001147|dip:DIP-1881N|ensemblfungi:YHR105W(gene)|ensemblfungi:YHR105W_mRNA(transcript)|go:"GO:0005768"(endosome)|go:"GO:0010008"(endosome membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|interpro:IPR001683(Phox-like)|interpro:IPR036871|interpro:IPR037917	-	isoform-comment:No experimental confirmation available.	crc64:2ADD21AF107094DC	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:1VqWIwPpWs6WjW8eDoJUHz2pegw9606	rogid:fUTJG8BaTveH3zB/0W1vNh4BU2Y559292	intact-crc:27339D08DE080056|rigid:Tc5Z00Ijf1H/4/CoUQ9k/8XVdxs	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8WWB3	uniprotkb:P53829	intact:EBI-740680|ensembl:ENSP00000361276|ensembl:ENSP00000361278|ensembl:ENSP00000402890|uniprotkb:Q5QP03|uniprotkb:Q5QP04|uniprotkb:Q6WNP4|uniprotkb:Q6ZU87|uniprotkb:A8K927	intact:EBI-28306|uniprotkb:D6W0Q5|ensemblfungi:YNL288W	psi-mi:dydc1_human(display_long)|uniprotkb:DYDC1(gene name)|psi-mi:DYDC1(display_short)|uniprotkb:DPY30D1(gene name synonym)|uniprotkb:RSD9(orf name)|uniprotkb:RSD-9(orf name)	psi-mi:caf40_yeast(display_long)|uniprotkb:YNL288W(locus name)|uniprotkb:N0540(orf name)|uniprotkb:40 kDa CCR4-associated factor(gene name synonym)|uniprotkb:CAF40(gene name)|psi-mi:CAF40(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553032|imex:IM-24995-3829	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_620167.1|ensembl:ENSG00000170788(gene)|ensembl:ENST00000372202(transcript)|ensembl:ENST00000372204(transcript)|ensembl:ENST00000421924(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0006348"|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|interpro:IPR007858(Dpy-30)|interpro:IPR037856|refseq:XP_011537636.1|refseq:XP_011537637.1|refseq:NP_001255982.1|refseq:XP_005269606.1|refseq:XP_005269607.1	refseq:NP_014111.1|sgd:S000005232|dip:DIP-1995N|mint:P53829|ensemblfungi:YNL288W(gene)|ensemblfungi:YNL288W_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR007216(Cell differentiation, Rcd1-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:4CV5	-	-	crc64:F3DBABE6AD3C7F3C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:W6GUazYFXZGHGijUBpAJ5GiRuXA9606	rogid:etuSSgFGQOcgxPDexEXUqQg6H5s559292	intact-crc:483D9DD0F36CAA2D|rigid:3uApgK1+ckwOYgj1xkBsy5HP/P4	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8WXE1-3	uniprotkb:P32502	intact:EBI-11524582|ensembl:ENSP00000400930	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:q8wxe1-3(display_long)|uniprotkb:ATRIP(gene name)|psi-mi:ATRIP(display_short)|uniprotkb:AGS1(gene name synonym)|uniprotkb:ATM and Rad3-related-interacting protein(gene name synonym)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553060|imex:IM-24995-3836	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-747353(isoform-parent)|ensembl:ENSG00000164053(gene)|ensembl:ENST00000412052(transcript)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731	-	isoform-comment:No experimental confirmation available.	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:NKCjy1jGZEySEhUOf8rJ6h9pyxY9606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:F071F0650F637408|rigid:8PRM6TuIS7PPBbI7W0s2tbT/MLs	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8WXE1-3	uniprotkb:P32902	intact:EBI-11524582|ensembl:ENSP00000400930	intact:EBI-16248|ensemblfungi:YHL004W|uniprotkb:D3DKR0	psi-mi:q8wxe1-3(display_long)|uniprotkb:ATRIP(gene name)|psi-mi:ATRIP(display_short)|uniprotkb:AGS1(gene name synonym)|uniprotkb:ATM and Rad3-related-interacting protein(gene name synonym)	psi-mi:rt04_yeast(display_long)|uniprotkb:MRP4(gene name)|psi-mi:MRP4(display_short)|uniprotkb:MRP4A(gene name synonym)|uniprotkb:Mitochondrial small ribosomal subunit protein uS2m(gene name synonym)|uniprotkb:YHL004W(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553056|imex:IM-24995-3835	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-747353(isoform-parent)|ensembl:ENSG00000164053(gene)|ensembl:ENST00000412052(transcript)	ensemblfungi:YHL004W(gene)|ensemblfungi:YHL004W_mRNA(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR001865(Ribosomal protein S2)|interpro:IPR005706(Ribosomal protein S2, bacterial-type)|interpro:IPR018130|interpro:IPR023591|rcsb pdb:5MRC|rcsb pdb:5MRE|rcsb pdb:5MRF|refseq:NP_011859.1|sgd:S000000996|dip:DIP-5035N|mint:P32902	-	isoform-comment:No experimental confirmation available.	crc64:81A1CB33134BC559	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:NKCjy1jGZEySEhUOf8rJ6h9pyxY9606	rogid:BlL3W6HUN+uAKF/AxwlV1zT5YZQ559292	intact-crc:BAA5B96023A7ABFD|rigid:q4kObxihjWSQ6C9C1opduIO+Xp0	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8WWB3	uniprotkb:Q07978	intact:EBI-740680|ensembl:ENSP00000361276|ensembl:ENSP00000361278|ensembl:ENSP00000402890|uniprotkb:Q5QP03|uniprotkb:Q5QP04|uniprotkb:Q6WNP4|uniprotkb:Q6ZU87|uniprotkb:A8K927	intact:EBI-38683|uniprotkb:D6VY33|ensemblfungi:YLR031W	psi-mi:dydc1_human(display_long)|uniprotkb:DYDC1(gene name)|psi-mi:DYDC1(display_short)|uniprotkb:DPY30D1(gene name synonym)|uniprotkb:RSD9(orf name)|uniprotkb:RSD-9(orf name)	psi-mi:yl031_yeast(display_long)|uniprotkb:YLR031W(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553044|imex:IM-24995-3832	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_620167.1|ensembl:ENSG00000170788(gene)|ensembl:ENST00000372202(transcript)|ensembl:ENST00000372204(transcript)|ensembl:ENST00000421924(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0006348"|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|interpro:IPR007858(Dpy-30)|interpro:IPR037856|refseq:XP_011537636.1|refseq:XP_011537637.1|refseq:NP_001255982.1|refseq:XP_005269606.1|refseq:XP_005269607.1	sgd:S000004021|refseq:NP_013131.1|dip:DIP-4435N|ensemblfungi:YLR031W(gene)|ensemblfungi:YLR031W_mRNA(transcript)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:W6GUazYFXZGHGijUBpAJ5GiRuXA9606	rogid:T3r2tgTMVd+abiwf7/Ccb/QJ2ZQ559292	intact-crc:FC3FB043CEEF4F2A|rigid:L6aPc/q8SYVlXcsNAWhyn+g24+U	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P32902	uniprotkb:Q8WWB3	intact:EBI-16248|ensemblfungi:YHL004W|uniprotkb:D3DKR0	intact:EBI-740680|ensembl:ENSP00000361276|ensembl:ENSP00000361278|ensembl:ENSP00000402890|uniprotkb:Q5QP03|uniprotkb:Q5QP04|uniprotkb:Q6WNP4|uniprotkb:Q6ZU87|uniprotkb:A8K927	psi-mi:rt04_yeast(display_long)|uniprotkb:MRP4(gene name)|psi-mi:MRP4(display_short)|uniprotkb:MRP4A(gene name synonym)|uniprotkb:Mitochondrial small ribosomal subunit protein uS2m(gene name synonym)|uniprotkb:YHL004W(locus name)	psi-mi:dydc1_human(display_long)|uniprotkb:DYDC1(gene name)|psi-mi:DYDC1(display_short)|uniprotkb:DPY30D1(gene name synonym)|uniprotkb:RSD9(orf name)|uniprotkb:RSD-9(orf name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553048|imex:IM-24995-3833	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YHL004W(gene)|ensemblfungi:YHL004W_mRNA(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR001865(Ribosomal protein S2)|interpro:IPR005706(Ribosomal protein S2, bacterial-type)|interpro:IPR018130|interpro:IPR023591|rcsb pdb:5MRC|rcsb pdb:5MRE|rcsb pdb:5MRF|refseq:NP_011859.1|sgd:S000000996|dip:DIP-5035N|mint:P32902	refseq:NP_620167.1|ensembl:ENSG00000170788(gene)|ensembl:ENST00000372202(transcript)|ensembl:ENST00000372204(transcript)|ensembl:ENST00000421924(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0006348"|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|interpro:IPR007858(Dpy-30)|interpro:IPR037856|refseq:XP_011537636.1|refseq:XP_011537637.1|refseq:NP_001255982.1|refseq:XP_005269606.1|refseq:XP_005269607.1	-	crc64:81A1CB33134BC559	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:BlL3W6HUN+uAKF/AxwlV1zT5YZQ559292	rogid:W6GUazYFXZGHGijUBpAJ5GiRuXA9606	intact-crc:BFD702CEA431BB03|rigid:WzjHYqsDg3w44cS5krinjUt9vpI	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P47041	uniprotkb:Q8WXE1-3	intact:EBI-25889|uniprotkb:D6VWC4|ensemblfungi:YJL058C	intact:EBI-11524582|ensembl:ENSP00000400930	psi-mi:bit61_yeast(display_long)|uniprotkb:YJL058C(locus name)|uniprotkb:J1141(orf name)|uniprotkb:61 kDa binding partner of TOR2 protein(gene name synonym)|uniprotkb:BIT61(gene name)|psi-mi:BIT61(display_short)	psi-mi:q8wxe1-3(display_long)|uniprotkb:ATRIP(gene name)|psi-mi:ATRIP(display_short)|uniprotkb:AGS1(gene name synonym)|uniprotkb:ATM and Rad3-related-interacting protein(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553052|imex:IM-24995-3834	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012477.1|sgd:S000003594|dip:DIP-1444N|reactome:R-SCE-1257604|reactome:R-SCE-389357|reactome:R-SCE-5218920|ensemblfungi:YJL058C(gene)|ensemblfungi:YJL058C_mRNA(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005737"(cytoplasm)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0031932"(TORC2 complex)|go:"GO:0038203"(TORC2 signaling)|go:"GO:0071944"(cell periphery)|interpro:IPR013745(HbrB-like)|reactome:R-SCE-6804757	intact:EBI-747353(isoform-parent)|ensembl:ENSG00000164053(gene)|ensembl:ENST00000412052(transcript)	-	crc64:99F0F96840311F4B	isoform-comment:No experimental confirmation available.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:H+zcKwbWL90wsmvD9TfWYmEbRwM559292	rogid:NKCjy1jGZEySEhUOf8rJ6h9pyxY9606	intact-crc:7097980CFF54A171|rigid:CTDrD9+Jv3vAlskisDMRa4OYf/k	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8WZ19	uniprotkb:Q12354	intact:EBI-742916|ensembl:ENSP00000311202|ensembl:ENSP00000455785|uniprotkb:Q96P93|uniprotkb:Q96SA1|uniprotkb:A8K0R5	intact:EBI-37732|uniprotkb:D6VYB6|ensemblfungi:YLR118C	psi-mi:bacd1_human(display_long)|uniprotkb:Polymerase delta-interacting protein 1(gene name synonym)|uniprotkb:TNFAIP1-like protein(gene name synonym)|uniprotkb:KCTD13(gene name)|psi-mi:KCTD13(display_short)|uniprotkb:PDIP1(gene name synonym)|uniprotkb:POLDIP1(gene name synonym)|uniprotkb:FKSG86(orf name)|uniprotkb:PP6832(orf name)|uniprotkb:BACURD1(gene name synonym)|uniprotkb:BTB/POZ domain-containing protein KCTD13(gene name synonym)	psi-mi:apth1_yeast(display_long)|uniprotkb:L2955(orf name)|uniprotkb:YLR118C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553076|imex:IM-24995-3840	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_849194.1|ensembl:ENSG00000174943(gene)|ensembl:ENST00000308768(transcript)|ensembl:ENST00000568000(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016477"(cell migration)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0043149"(stress fiber assembly)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0050806"(positive regulation of synaptic transmission)|go:"GO:0051260"(protein homooligomerization)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR003131(Potassium channel, voltage dependent, Kv,  tetramerisation)|interpro:IPR011333(BTB/POZ fold)|mint:Q8WZ19|rcsb pdb:4UIJ|reactome:R-HSA-9696264|reactome:R-HSA-9696270	refseq:NP_013219.1|sgd:S000004108|reactome:R-SCE-203615|dip:DIP-2830N|reactome:R-SCE-9648002|ensemblfungi:YLR118C(gene)|ensemblfungi:YLR118C_mRNA(transcript)|go:"GO:0002084"(protein depalmitoylation)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0008474"("palmitoyl-(protein) hydrolase activity")|go:"GO:0035601"(protein deacylation)|go:"GO:0052689"(carboxylic ester hydrolase activity)|interpro:IPR003140(Phospholipase/carboxylesterase)|interpro:IPR029058	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:hAH5yJEoda0H1anmnSXWHO0o1ZM9606	rogid:z4WO9062CHwiLV2c1/+N6zn0AEE559292	intact-crc:A6EEFCED73511E5E|rigid:sbZUfm+kDbyU4Pw91svZXTROBu0	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8WXE1-3	uniprotkb:P25377	intact:EBI-11524582|ensembl:ENSP00000400930	intact:EBI-2347652|uniprotkb:D6VRA5|ensemblfungi:YCR105W	psi-mi:q8wxe1-3(display_long)|uniprotkb:ATRIP(gene name)|psi-mi:ATRIP(display_short)|uniprotkb:AGS1(gene name synonym)|uniprotkb:ATM and Rad3-related-interacting protein(gene name synonym)	psi-mi:adh7_yeast(display_long)|uniprotkb:ADH7(gene name)|psi-mi:ADH7(display_short)|uniprotkb:NADP-dependent alcohol dehydrogenase VII(gene name synonym)|uniprotkb:YCR105W(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553064|imex:IM-24995-3837	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-747353(isoform-parent)|ensembl:ENSG00000164053(gene)|ensembl:ENST00000412052(transcript)	refseq:NP_010030.1|sgd:S000000702|dip:DIP-7661N|mint:P25377|ensemblfungi:YCR105W(gene)|ensemblfungi:YCR105W_mRNA(transcript)|go:"GO:0006066"(alcohol metabolic process)|go:"GO:0008106"("alcohol dehydrogenase (NADP+) activity")|go:"GO:0008270"(zinc ion binding)|go:"GO:0016616"(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|interpro:IPR002328(Alcohol dehydrogenase, zinc-containing, conserved site)|interpro:IPR011032(GroES-like)|interpro:IPR013149(Alcohol dehydrogenase, zinc-binding)|interpro:IPR013154(Alcohol dehydrogenase GroES-like)|interpro:IPR020843|interpro:IPR029752|interpro:IPR036291	-	isoform-comment:No experimental confirmation available.	crc64:BFB0E6C5F93D3F07	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:NKCjy1jGZEySEhUOf8rJ6h9pyxY9606	rogid:PGCt+bqhn63vUVgS5IKrrOukXgg559292	intact-crc:3359FC0510FFA5DB|rigid:QIrliXieSc8Ux2A78vwZ+kw2xIU	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8WXE1-3	uniprotkb:P53286	intact:EBI-11524582|ensembl:ENSP00000400930	intact:EBI-3796|uniprotkb:D6VUS2|ensemblfungi:YGR142W	psi-mi:q8wxe1-3(display_long)|uniprotkb:ATRIP(gene name)|psi-mi:ATRIP(display_short)|uniprotkb:AGS1(gene name synonym)|uniprotkb:ATM and Rad3-related-interacting protein(gene name synonym)	psi-mi:btn2_yeast(display_long)|uniprotkb:YGR142W(locus name)|uniprotkb:BTN2(gene name)|psi-mi:BTN2(display_short)|uniprotkb:Batten disease protein 2(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553068|imex:IM-24995-3838	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-747353(isoform-parent)|ensembl:ENSG00000164053(gene)|ensembl:ENST00000412052(transcript)	sgd:S000003374|refseq:NP_011658.3|dip:DIP-5534N|mint:P53286|ensemblfungi:YGR142W(gene)|ensemblfungi:YGR142W_mRNA(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005634"(nucleus)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006865"(amino acid transport)|go:"GO:0006885"(regulation of pH)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051087"(chaperone binding)|go:"GO:0140311"(protein sequestering activity)	-	isoform-comment:No experimental confirmation available.	crc64:E7AE1EB1E3612F3E	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:NKCjy1jGZEySEhUOf8rJ6h9pyxY9606	rogid:Cu27xkwGMNyS4zLvUaG1UeH2mE0559292	intact-crc:F0403DCE8C376659|rigid:QecK8SllrIfV258shEgboJCRAHg	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P28004	uniprotkb:Q8WXE1-3	intact:EBI-20640|uniprotkb:D6VPI6|ensemblfungi:YAL032C	intact:EBI-11524582|ensembl:ENSP00000400930	psi-mi:prp45_yeast(display_long)|uniprotkb:YAL032C(locus name)|uniprotkb:PRP45(gene name)|psi-mi:PRP45(display_short)|uniprotkb:FUN20(gene name synonym)	psi-mi:q8wxe1-3(display_long)|uniprotkb:ATRIP(gene name)|psi-mi:ATRIP(display_short)|uniprotkb:AGS1(gene name synonym)|uniprotkb:ATM and Rad3-related-interacting protein(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553072|imex:IM-24995-3839	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009370.1|sgd:S000000030|ensemblfungi:YAL032C(gene)|ensemblfungi:YAL032C_mRNA(transcript)|go:"GO:0000350"(generation of catalytic spliceosome for second transesterification step)|go:"GO:0005634"(nucleus)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|interpro:IPR004015(SKIP/SNW)|interpro:IPR017862|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|dip:DIP-2774N|mint:P28004	intact:EBI-747353(isoform-parent)|ensembl:ENSG00000164053(gene)|ensembl:ENST00000412052(transcript)	-	crc64:FE5A724186D7FE84	isoform-comment:No experimental confirmation available.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:qoHF1UsO3k+JOTOfigSuy2P84/k559292	rogid:NKCjy1jGZEySEhUOf8rJ6h9pyxY9606	intact-crc:831E1ED8EE36EBEF|rigid:J70e7vmfBgj+wUTeeimePrYnIzM	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q92734	uniprotkb:Q12259	intact:EBI-357061|uniprotkb:Q15656|intact:EBI-357314|uniprotkb:Q969I2|uniprotkb:D3DN49|uniprotkb:K0J5S8|uniprotkb:K0J6K2|intact:EBI-28969365|ensembl:ENSP00000240851|ensembl:ENSP00000419960|ensembl:ENSP00000420797|ensembl:ENSP00000501815|ensembl:ENSP00000502071|ensembl:ENSP00000502450|ensembl:ENSP00000502592|ensembl:ENSP00000502734|uniprotkb:G5E9V1	intact:EBI-30776|uniprotkb:D6VYA8|ensemblfungi:YLR108C	psi-mi:tfg_human(display_long)|uniprotkb:TFG(gene name)|psi-mi:TFG(display_short)|uniprotkb:TRK-fused gene protein(gene name synonym)	psi-mi:yl108_yeast(display_long)|uniprotkb:L2913(orf name)|uniprotkb:YLR108C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553096|imex:IM-24995-3845	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001007566.1|refseq:NP_001182407.1|refseq:NP_001182408.1|refseq:NP_006061.2|ensembl:ENSP00000240851|ensembl:ENST00000463568|ensembl:ENSP00000419504|ensembl:ENST00000476228|ensembl:ENSP00000417952|ensembl:ENSP00000420797|ensembl:ENSP00000419960|ensembl:ENST00000615993|ensembl:ENSP00000479269|ensembl:ENST00000620299|ensembl:ENSP00000479981|ensembl:ENSP00000502734|ensembl:ENST00000674645|ensembl:ENSP00000501892|ensembl:ENST00000674758|ensembl:ENSP00000502502|ensembl:ENST00000675047|ensembl:ENSP00000502497|ensembl:ENSP00000502592|ensembl:ENST00000675420|ensembl:ENSP00000502516|ensembl:ENSP00000502450|ensembl:ENST00000675543|ensembl:ENSP00000501815|ensembl:ENST00000675586|ensembl:ENSP00000502329|ensembl:ENST00000676111|ensembl:ENSP00000502139|ensembl:ENST00000676308|ensembl:ENSP00000502697|ensembl:ENSP00000502071|ensembl:ENST00000676431|ensembl:ENSP00000502698|ensembl:ENSP00000502229|refseq:XP_006713535.1|refseq:XP_006713536.1|ensembl:ENSG00000114354(gene)|ensembl:ENST00000240851(transcript)|ensembl:ENST00000487505(transcript)|ensembl:ENST00000490574(transcript)|ensembl:ENST00000674615(transcript)|ensembl:ENST00000675243(transcript)|ensembl:ENST00000675499(transcript)|ensembl:ENST00000675553(transcript)|ensembl:ENST00000676395(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048208"(COPII vesicle coating)|go:"GO:0070971"(endoplasmic reticulum exit site)|interpro:IPR000270(Octicosapeptide/Phox/Bem1p)|interpro:IPR033512|interpro:IPR034857|mint:Q92734|reactome:R-HSA-204005|refseq:XP_011510636.1|refseq:XP_005247123.1|refseq:XP_016861016.1|refseq:XP_016861017.1|refseq:XP_016861018.1|refseq:XP_016861019.1	refseq:NP_013209.1|sgd:S000004098|dip:DIP-4075N|ensemblfungi:YLR108C(gene)|ensemblfungi:YLR108C_mRNA(transcript)|go:"GO:0005634"(nucleus)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:y7aghh0X3Ewgpzcx5h5nB+X2dII9606	rogid:CzknxXhhvgMp3J0/oi197EgZ05U559292	intact-crc:6FCFD6754B29D51E|rigid:Kmbywoug59wyzgm0IQiNuBFMdqc	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q92734	uniprotkb:P40956	intact:EBI-357061|uniprotkb:Q15656|intact:EBI-357314|uniprotkb:Q969I2|uniprotkb:D3DN49|uniprotkb:K0J5S8|uniprotkb:K0J6K2|intact:EBI-28969365|ensembl:ENSP00000240851|ensembl:ENSP00000419960|ensembl:ENSP00000420797|ensembl:ENSP00000501815|ensembl:ENSP00000502071|ensembl:ENSP00000502450|ensembl:ENSP00000502592|ensembl:ENSP00000502734|uniprotkb:G5E9V1	intact:EBI-7968|uniprotkb:D6VTX2|ensemblfungi:YGL181W	psi-mi:tfg_human(display_long)|uniprotkb:TFG(gene name)|psi-mi:TFG(display_short)|uniprotkb:TRK-fused gene protein(gene name synonym)	psi-mi:gts1_yeast(display_long)|uniprotkb:YGL181W(locus name)|uniprotkb:GTS1(gene name)|psi-mi:GTS1(display_short)|uniprotkb:LSR1(gene name synonym)|uniprotkb:Protein LSR1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553092|imex:IM-24995-3844	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001007566.1|refseq:NP_001182407.1|refseq:NP_001182408.1|refseq:NP_006061.2|ensembl:ENSP00000240851|ensembl:ENST00000463568|ensembl:ENSP00000419504|ensembl:ENST00000476228|ensembl:ENSP00000417952|ensembl:ENSP00000420797|ensembl:ENSP00000419960|ensembl:ENST00000615993|ensembl:ENSP00000479269|ensembl:ENST00000620299|ensembl:ENSP00000479981|ensembl:ENSP00000502734|ensembl:ENST00000674645|ensembl:ENSP00000501892|ensembl:ENST00000674758|ensembl:ENSP00000502502|ensembl:ENST00000675047|ensembl:ENSP00000502497|ensembl:ENSP00000502592|ensembl:ENST00000675420|ensembl:ENSP00000502516|ensembl:ENSP00000502450|ensembl:ENST00000675543|ensembl:ENSP00000501815|ensembl:ENST00000675586|ensembl:ENSP00000502329|ensembl:ENST00000676111|ensembl:ENSP00000502139|ensembl:ENST00000676308|ensembl:ENSP00000502697|ensembl:ENSP00000502071|ensembl:ENST00000676431|ensembl:ENSP00000502698|ensembl:ENSP00000502229|refseq:XP_006713535.1|refseq:XP_006713536.1|ensembl:ENSG00000114354(gene)|ensembl:ENST00000240851(transcript)|ensembl:ENST00000487505(transcript)|ensembl:ENST00000490574(transcript)|ensembl:ENST00000674615(transcript)|ensembl:ENST00000675243(transcript)|ensembl:ENST00000675499(transcript)|ensembl:ENST00000675553(transcript)|ensembl:ENST00000676395(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048208"(COPII vesicle coating)|go:"GO:0070971"(endoplasmic reticulum exit site)|interpro:IPR000270(Octicosapeptide/Phox/Bem1p)|interpro:IPR033512|interpro:IPR034857|mint:Q92734|reactome:R-HSA-204005|refseq:XP_011510636.1|refseq:XP_005247123.1|refseq:XP_016861016.1|refseq:XP_016861017.1|refseq:XP_016861018.1|refseq:XP_016861019.1	refseq:NP_011334.1|sgd:S000003149|mint:P40956|dip:DIP-2746N|ensemblfungi:YGL181W(gene)|ensemblfungi:YGL181W_mRNA(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0006897"(endocytosis)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010512"(negative regulation of phosphatidylinositol biosynthetic process)|go:"GO:0030479"(actin cortical patch)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR037278|interpro:IPR038508	-	-	crc64:D687E3BF6B620795	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:y7aghh0X3Ewgpzcx5h5nB+X2dII9606	rogid:8kgpssCRrHiTHsFaOH2nDK6EIjk559292	intact-crc:ADBF3C8EC9218CE9|rigid:/k+kbKNm/+JBeWuHk0bYBxyr74M	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P38182	uniprotkb:Q92609	intact:EBI-2684|uniprotkb:D6VPS5|ensemblfungi:YBL078C	intact:EBI-742381|uniprotkb:A6NP25|intact:EBI-28978959|ensembl:ENSP00000253692|ensembl:ENSP00000398127|uniprotkb:C9JP52	psi-mi:atg8_yeast(display_long)|uniprotkb:ATG8(gene name)|psi-mi:ATG8(display_short)|uniprotkb:APG8(gene name synonym)|uniprotkb:AUT7(gene name synonym)|uniprotkb:YBL078C(locus name)|uniprotkb:YBL0732(orf name)|uniprotkb:CVT5(gene name synonym)|uniprotkb:Autophagy-related ubiquitin-like modifier ATG8(gene name synonym)|uniprotkb:Cytoplasm to vacuole targeting protein 5(gene name synonym)	psi-mi:tbcd5_human(display_long)|uniprotkb:TBC1D5(gene name)|psi-mi:TBC1D5(display_short)|uniprotkb:KIAA0210(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553080|imex:IM-24995-3841	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000000174|refseq:NP_009475.1|dip:DIP-1197N|mint:P38182|ensemblfungi:YBL078C(gene)|ensemblfungi:YBL078C_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006914"(autophagy)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0008429"(phosphatidylethanolamine binding)|go:"GO:0016236"(macroautophagy)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0031386"(protein tag)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0033110"(Cvt vesicle membrane)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0034629"|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|go:"GO:0061025"(membrane fusion)|go:"GO:0061709"(reticulophagy)|go:"GO:0071211"(protein targeting to vacuole involved in autophagy)|go:"GO:0120095"(vacuole-isolation membrane contact site)|go:"GO:1905153"(regulation of membrane invagination)|interpro:IPR004241("Light chain 3 (LC3)")|interpro:IPR029071|rcsb pdb:2KQ7|rcsb pdb:2KWC|rcsb pdb:2LI5|rcsb pdb:2ZPN|rcsb pdb:3RUI|rcsb pdb:3VH3|rcsb pdb:3VH4|rcsb pdb:3VXW|rcsb pdb:5YEC|rcsb pdb:6AAG|rcsb pdb:6WY6|rcsb pdb:7BRN|reactome:R-SCE-1632852|reactome:R-SCE-8854214|reactome:R-SCE-8934903	ensembl:ENSP00000253692|ensembl:ENSP00000398127|ensembl:ENSP00000402935|ensembl:ENST00000446818|refseq:NP_055559.1|refseq:XP_011532586.1|refseq:XP_011532583.1|refseq:XP_011532585.1|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005776"(autophagosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006914"(autophagy)|go:"GO:0010008"(endosome membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0030904"(retromer complex)|go:"GO:0035612"(AP-2 adaptor complex binding)|ensembl:ENSG00000131374(gene)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042594"(response to starvation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:1905394"(retromer complex binding)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR035969|mint:Q92609|rcsb pdb:5GTU|ensembl:ENST00000253692(transcript)|ensembl:ENST00000429383(transcript)|go:"GO:0002092"(positive regulation of receptor internalization)|refseq:NP_001127853.1|refseq:XP_006713493.1|refseq:XP_016863041.1|refseq:XP_016863042.1|refseq:XP_016863043.1|refseq:XP_016863044.1|refseq:XP_016863045.1|refseq:XP_016863046.1	-	crc64:1246CEFF5A038819	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:UlmpBW3JgdYFHLkZCQeJeb7DpK4559292	rogid:GZ7WP4suMiSPSAJK0TZWQMQZxzU9606	intact-crc:CCA9B2EDEC15AC87|rigid:7v+nlQJThCowWc7ZH5aEqne9ilQ	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q07540	uniprotkb:Q92609	intact:EBI-2206814|uniprotkb:D6VRN0|ensemblfungi:YDL120W	intact:EBI-742381|uniprotkb:A6NP25|intact:EBI-28978959|ensembl:ENSP00000253692|ensembl:ENSP00000398127|uniprotkb:C9JP52	psi-mi:frda_yeast(display_long)|uniprotkb:YFH1(gene name)|psi-mi:YFH1(display_short)|uniprotkb:YDL120W(locus name)	psi-mi:tbcd5_human(display_long)|uniprotkb:TBC1D5(gene name)|psi-mi:TBC1D5(display_short)|uniprotkb:KIAA0210(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553084|imex:IM-24995-3842	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-7485N|refseq:NP_010163.1|sgd:S000002278|mint:Q07540|ensemblfungi:YDL120W(gene)|ensemblfungi:YDL120W_mRNA(transcript)|go:"GO:0004322"(ferroxidase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006121"(mitochondrial electron transport, succinate to ubiquinone)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0006783"(heme biosynthetic process)|go:"GO:0006811"(ion transport)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008199"(ferric iron binding)|go:"GO:0010040"("response to iron(II) ion")|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0018283"(iron incorporation into metallo-sulfur cluster)|go:"GO:0034986"(iron chaperone activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|interpro:IPR002908(Frataxin-like)|interpro:IPR017789(Frataxin)|interpro:IPR020895|interpro:IPR036524|rcsb pdb:2FQL|rcsb pdb:2GA5|rcsb pdb:3OEQ|rcsb pdb:3OER|rcsb pdb:4EC2|rcsb pdb:5T0V|rcsb pdb:5TRE|reactome:R-SCE-1268020|reactome:R-SCE-1362409|go:"GO:0008198"(ferrous iron binding)	ensembl:ENSP00000253692|ensembl:ENSP00000398127|ensembl:ENSP00000402935|ensembl:ENST00000446818|refseq:NP_055559.1|refseq:XP_011532586.1|refseq:XP_011532583.1|refseq:XP_011532585.1|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005776"(autophagosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006914"(autophagy)|go:"GO:0010008"(endosome membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0030904"(retromer complex)|go:"GO:0035612"(AP-2 adaptor complex binding)|ensembl:ENSG00000131374(gene)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042594"(response to starvation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:1905394"(retromer complex binding)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR035969|mint:Q92609|rcsb pdb:5GTU|ensembl:ENST00000253692(transcript)|ensembl:ENST00000429383(transcript)|go:"GO:0002092"(positive regulation of receptor internalization)|refseq:NP_001127853.1|refseq:XP_006713493.1|refseq:XP_016863041.1|refseq:XP_016863042.1|refseq:XP_016863043.1|refseq:XP_016863044.1|refseq:XP_016863045.1|refseq:XP_016863046.1	-	crc64:AB1FF7478EF0E5D6	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:4UcroTodEXb/5+xHGpnXDXf/rd8559292	rogid:GZ7WP4suMiSPSAJK0TZWQMQZxzU9606	intact-crc:0188745C308A2EFA|rigid:ygkxYyPIYj4peP+w7qkAkVu9sz0	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P38302	uniprotkb:Q92733	intact:EBI-20921|uniprotkb:D6VQI3|ensemblfungi:YBR188C	intact:EBI-4397741|uniprotkb:A8K1F7|uniprotkb:O00665|uniprotkb:O00724|uniprotkb:Q5SZ06|ensembl:ENSP00000271526	psi-mi:ntc20_yeast(display_long)|uniprotkb:YBR188C(locus name)|uniprotkb:YBR1316(orf name)|uniprotkb:NTC20(gene name)|psi-mi:NTC20(display_short)|uniprotkb:SNT384(gene name synonym)|uniprotkb:PRP19-associated complex protein 20(gene name synonym)|uniprotkb:Synergistic to PRP19 mutation protein 384(gene name synonym)	psi-mi:prcc_human(display_long)|uniprotkb:PRCC(gene name)|psi-mi:PRCC(display_short)|uniprotkb:TPRC(gene name synonym)|uniprotkb:Papillary renal cell carcinoma translocation-associated gene protein(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553088|imex:IM-24995-3843	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009747.3|sgd:S000000392|mint:P38302|ensemblfungi:YBR188C(gene)|ensemblfungi:YBR188C_mRNA(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000974"(Prp19 complex)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|dip:DIP-1683N	refseq:NP_005964.3|ensembl:ENSG00000143294(gene)|ensembl:ENST00000271526(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0016607"(nuclear speck)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR018800|mint:Q92733|reactome:R-HSA-72163	-	crc64:15C5234B25213223	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Ucc4R0lhhhAQfrsXvs+BtCnuJQg559292	rogid:Q6sXpPQm/3mr9HS0XF0VdxLSFzc9606	intact-crc:C09AD7F53BAB3FC1|rigid:CFrGe6z8//a9KmB1lr9NaETc6wU	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q92997	uniprotkb:P33750	intact:EBI-739789|uniprotkb:O14642|uniprotkb:Q13531|uniprotkb:Q8N5E9|uniprotkb:Q92607|uniprotkb:D3DNT0|intact:EBI-11081380|uniprotkb:B4E3E5|ensembl:ENSP00000316054	intact:EBI-17651|uniprotkb:D6VXZ1|ensemblfungi:YLL011W	psi-mi:dvl3_human(display_long)|uniprotkb:DVL3(gene name)|psi-mi:DVL3(display_short)|uniprotkb:KIAA0208(gene name synonym)|uniprotkb:DSH homolog 3(gene name synonym)	psi-mi:dca13_yeast(display_long)|uniprotkb:SOF1(gene name)|psi-mi:SOF1(display_short)|uniprotkb:YLL011W(locus name)|uniprotkb:L1339(orf name)|uniprotkb:U3 small nucleolar RNA-associated protein SOF1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553116|imex:IM-24995-3850	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004414.3|dip:DIP-34509N|ensembl:ENSG00000161202(gene)|ensembl:ENST00000313143(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002020"(protease binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005109"(frizzled binding)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0038031"(non-canonical Wnt signaling pathway via JNK cascade)|go:"GO:0042493"|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050821"(protein stabilization)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0150012"(positive regulation of neuron projection arborization)|go:"GO:1903827"|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008342(Dishevelled-3 protein, C-terminal)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:Q92997|rcsb pdb:6V7O|rcsb pdb:6ZC6|rcsb pdb:6ZC8|reactome:R-HSA-201681|reactome:R-HSA-201688|reactome:R-HSA-4086400|reactome:R-HSA-4641258|reactome:R-HSA-4641262|reactome:R-HSA-5368598|reactome:R-HSA-5663220|reactome:R-HSA-9673324	ensemblfungi:YLL011W(gene)|ensemblfungi:YLL011W_mRNA(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003729"(mRNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0030686"(90S preribosome)|go:"GO:0032040"(small-subunit processome)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR007287(Sof1-like protein)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR020472|interpro:IPR036322|rcsb pdb:5WLC|rcsb pdb:6KE6|rcsb pdb:6LQP|rcsb pdb:6LQQ|rcsb pdb:6LQR|rcsb pdb:6LQS|rcsb pdb:6LQT|rcsb pdb:6LQU|rcsb pdb:6LQV|rcsb pdb:6ND4|rcsb pdb:6ZQA|rcsb pdb:6ZQB|rcsb pdb:6ZQC|rcsb pdb:6ZQD|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-6791226|refseq:NP_013090.1|sgd:S000003934|dip:DIP-746N|mint:P33750	-	-	crc64:4B28371CC61DE7E4	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:yJ3YIp5IhvKTQwa3bK5yTjNyqXk9606	rogid:stTLdABNsa3SvTkNOZBteSNAVJA559292	intact-crc:63C407E0047C32EC|rigid:MKlnYeGFXqo+k8PhzoxLEikprNI	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P05738	uniprotkb:Q92997	intact:EBI-15439|uniprotkb:D6VU02|ensemblfungi:YGL147C	intact:EBI-739789|uniprotkb:O14642|uniprotkb:Q13531|uniprotkb:Q8N5E9|uniprotkb:Q92607|uniprotkb:D3DNT0|intact:EBI-11081380|uniprotkb:B4E3E5|ensembl:ENSP00000316054	psi-mi:rl9a_yeast(display_long)|uniprotkb:RPL9A(gene name)|psi-mi:RPL9A(display_short)|uniprotkb:RPL9(gene name synonym)|uniprotkb:RPL8A(gene name synonym)|uniprotkb:L8(gene name synonym)|uniprotkb:YL11(gene name synonym)|uniprotkb:RP24(gene name synonym)|uniprotkb:YGL147C(locus name)|uniprotkb:Large ribosomal subunit protein uL6-A(gene name synonym)	psi-mi:dvl3_human(display_long)|uniprotkb:DVL3(gene name)|psi-mi:DVL3(display_short)|uniprotkb:KIAA0208(gene name synonym)|uniprotkb:DSH homolog 3(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553112|imex:IM-24995-3849	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003115|refseq:NP_011368.3|ensemblfungi:YGL147C(gene)|ensemblfungi:YGL147C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0019843"(rRNA binding)|go:"GO:0022625"(cytosolic large ribosomal subunit)|interpro:IPR000702(Ribosomal protein L6)|interpro:IPR002359(Ribosomal protein L6, conserved site-2)|interpro:IPR020040|interpro:IPR036789|rcsb pdb:1K5Y|rcsb pdb:3J16|rcsb pdb:3J6X|rcsb pdb:3J6Y|rcsb pdb:3J77|rcsb pdb:3J78|rcsb pdb:3JCT|rcsb pdb:4U3M|rcsb pdb:4U3N|rcsb pdb:4U3U|rcsb pdb:4U4N|rcsb pdb:4U4O|rcsb pdb:4U4Q|rcsb pdb:4U4R|rcsb pdb:4U4U|rcsb pdb:4U4Y|rcsb pdb:4U4Z|rcsb pdb:4U50|rcsb pdb:4U51|rcsb pdb:4U52|rcsb pdb:4U53|rcsb pdb:4U55|rcsb pdb:4U56|rcsb pdb:4U6F|rcsb pdb:4V4B|rcsb pdb:4V6I|rcsb pdb:4V7F|rcsb pdb:4V7R|rcsb pdb:4V88|rcsb pdb:4V8T|rcsb pdb:4V8Y|rcsb pdb:7NRD|rcsb pdb:4V8Z|rcsb pdb:4V91|rcsb pdb:5APN|rcsb pdb:5APO|rcsb pdb:5DAT|rcsb pdb:5DC3|rcsb pdb:5DGE|rcsb pdb:5DGF|rcsb pdb:5DGV|rcsb pdb:5FCI|rcsb pdb:5FCJ|rcsb pdb:5FL8|rcsb pdb:5GAK|rcsb pdb:5H4P|rcsb pdb:5I4L|rcsb pdb:5JCS|rcsb pdb:5JUO|rcsb pdb:5JUP|rcsb pdb:5JUS|rcsb pdb:5JUT|rcsb pdb:5JUU|rcsb pdb:5LYB|rcsb pdb:5M1J|rcsb pdb:5MC6|rcsb pdb:5MEI|rcsb pdb:5NDG|rcsb pdb:5NDV|rcsb pdb:5NDW|rcsb pdb:5OBM|rcsb pdb:5ON6|rcsb pdb:5T62|rcsb pdb:5T6R|rcsb pdb:5TBW|rcsb pdb:5TGA|rcsb pdb:5TGM|rcsb pdb:5Z3G|rcsb pdb:6ELZ|rcsb pdb:6EM1|rcsb pdb:6EM5|rcsb pdb:6FT6|rcsb pdb:6GQ1|rcsb pdb:6GQB|rcsb pdb:6GQV|rcsb pdb:6HD7|rcsb pdb:6HHQ|rcsb pdb:6I7O|rcsb pdb:6M62|rcsb pdb:6N8J|rcsb pdb:6N8K|rcsb pdb:6N8L|rcsb pdb:6N8M|rcsb pdb:6N8N|rcsb pdb:6N8O|rcsb pdb:6OIG|rcsb pdb:6Q8Y|rcsb pdb:6QIK|rcsb pdb:6QT0|rcsb pdb:6QTZ|rcsb pdb:6R84|rcsb pdb:6R86|rcsb pdb:6R87|rcsb pdb:6RI5|rcsb pdb:6RZZ|rcsb pdb:6S05|rcsb pdb:6S47|rcsb pdb:6SNT|rcsb pdb:6SV4|rcsb pdb:6T4Q|rcsb pdb:6T7I|rcsb pdb:6T7T|rcsb pdb:6T83|rcsb pdb:6TB3|rcsb pdb:6TNU|rcsb pdb:6YLG|rcsb pdb:6YLH|rcsb pdb:6YLX|rcsb pdb:6YLY|rcsb pdb:6Z6J|rcsb pdb:6Z6K|rcsb pdb:7AZY|rcsb pdb:7B7D|rcsb pdb:7BT6|rcsb pdb:7BTB|rcsb pdb:7NRC|dip:DIP-4826N	refseq:NP_004414.3|dip:DIP-34509N|ensembl:ENSG00000161202(gene)|ensembl:ENST00000313143(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002020"(protease binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005109"(frizzled binding)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0038031"(non-canonical Wnt signaling pathway via JNK cascade)|go:"GO:0042493"|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050821"(protein stabilization)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0150012"(positive regulation of neuron projection arborization)|go:"GO:1903827"|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008342(Dishevelled-3 protein, C-terminal)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:Q92997|rcsb pdb:6V7O|rcsb pdb:6ZC6|rcsb pdb:6ZC8|reactome:R-HSA-201681|reactome:R-HSA-201688|reactome:R-HSA-4086400|reactome:R-HSA-4641258|reactome:R-HSA-4641262|reactome:R-HSA-5368598|reactome:R-HSA-5663220|reactome:R-HSA-9673324	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:TCDvdj9QlqdgRadKyIWG7ane1hw559292	rogid:yJ3YIp5IhvKTQwa3bK5yTjNyqXk9606	intact-crc:CBCA3C592B77E111|rigid:zMFEPUFkowDpfM3kSMjbz6SoM/0	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q08686	uniprotkb:Q92748	intact:EBI-19264|uniprotkb:D6W2V2|ensemblfungi:YOR251C	intact:EBI-1749955|uniprotkb:B2R4W7|ensembl:ENSP00000281030	psi-mi:thtr_yeast(display_long)|uniprotkb:YOR251C(locus name)|uniprotkb:TUM1(gene name)|psi-mi:TUM1(display_short)|uniprotkb:Thiouridine modification protein 1(gene name synonym)	psi-mi:thrsp_human(display_long)|uniprotkb:THRSP(gene name)|psi-mi:THRSP(display_short)|uniprotkb:Spot 14 protein(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553100|imex:IM-24995-3846	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005777|ensemblfungi:YOR251C(gene)|ensemblfungi:YOR251C_mRNA(transcript)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0002143"(tRNA wobble position uridine thiolation)|go:"GO:0004792"(thiosulfate sulfurtransferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0019346"(transsulfuration)|interpro:IPR001307(Thiosulphate sulphurtransferase, conserved site)|interpro:IPR001763(Rhodanese-like)|interpro:IPR036873|rcsb pdb:3UTN|refseq:NP_014894.3|dip:DIP-4457N|reactome:R-SCE-1614558	dip:DIP-40451N|refseq:NP_003242.1|ensembl:ENSG00000151365(gene)|ensembl:ENST00000281030(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0009617"(response to bacterium)|go:"GO:0010866"(regulation of triglyceride biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046890"(regulation of lipid biosynthetic process)|interpro:IPR009786(Thyroid hormone-inducible hepatic Spot 14)|mint:Q92748|reactome:R-HSA-200425	-	crc64:F8082DF7CC279E82	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:Hd0nLXm0qNzaqJcSHt/nV73+Pko559292	rogid:tkQQSNiBkUIynoBVT5olWEkCX/o9606	intact-crc:43A5A025978C9866|rigid:frlWGUDksTUPQXs1A9qSmEDDGYs	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q92841	intact:EBI-11522220	intact:EBI-746012|uniprotkb:Q69YT1|uniprotkb:Q6ICD6|uniprotkb:H3BLZ8|uniprotkb:B1AHM0|ensembl:ENSP00000385536	-	psi-mi:ddx17_human(display_long)|uniprotkb:DEAD box protein 17(gene name synonym)|uniprotkb:RNA-dependent helicase p72(gene name synonym)|uniprotkb:DEAD box protein p72(gene name synonym)|uniprotkb:DDX17(gene name)|psi-mi:DDX17(display_short)|uniprotkb:DEAD box protein p82(gene name synonym)	psi-mi:lsb3(display_short)|psi-mi:EBI-11522220(display_long)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553104|imex:IM-24995-3847	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006377.2|ensembl:ENSG00000100201(gene)|ensembl:ENST00000403230(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006364"(rRNA processing)|go:"GO:0006396"(RNA processing)|go:"GO:0008186"(ATP-dependent activity, acting on RNA)|go:"GO:0010586"(miRNA metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0045445"(myoblast differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051607"(defense response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2001014"(regulation of skeletal muscle cell differentiation)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:Q92841|rcsb pdb:6UV0|rcsb pdb:6UV1|rcsb pdb:6UV2|rcsb pdb:6UV3|rcsb pdb:6UV4|reactome:R-HSA-3899300|dip:DIP-29843N	-	-	-	no-uniprot-update:	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:3UhUuhRSZg/zlM7UPDKYCqNmUho9606	rogid:lsGJZWImagMoiiCZztCcxCn2LlU4932	intact-crc:E4353C32B7405D21|rigid:v6GkDh8mDkD5LIPm/bIWOwh+zZ0	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q06630	uniprotkb:Q92997	intact:EBI-36794|uniprotkb:D6VSS5|ensemblfungi:YDR296W	intact:EBI-739789|uniprotkb:O14642|uniprotkb:Q13531|uniprotkb:Q8N5E9|uniprotkb:Q92607|uniprotkb:D3DNT0|intact:EBI-11081380|uniprotkb:B4E3E5|ensembl:ENSP00000316054	psi-mi:mhr1_yeast(display_long)|uniprotkb:MHR1(gene name)|psi-mi:MHR1(display_short)|uniprotkb:YDR296W(locus name)|uniprotkb:Cross-linked transcription component 1(gene name synonym)|uniprotkb:XTC1(gene name synonym)|uniprotkb:Mitochondrial large ribosomal subunit protein mL67(gene name synonym)	psi-mi:dvl3_human(display_long)|uniprotkb:DVL3(gene name)|psi-mi:DVL3(display_short)|uniprotkb:KIAA0208(gene name synonym)|uniprotkb:DSH homolog 3(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553108|imex:IM-24995-3848	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002704|refseq:NP_010582.3|mint:Q06630|dip:DIP-5727N|ensemblfungi:YDR296W(gene)|ensemblfungi:YDR296W_mRNA(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0000150"(DNA strand exchange activity)|go:"GO:0003677"(DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0006310"(DNA recombination)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0032543"(mitochondrial translation)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0090297"(positive regulation of mitochondrial DNA replication)|interpro:IPR024629|rcsb pdb:3J6B|rcsb pdb:5MRC|rcsb pdb:5MRE|rcsb pdb:5MRF	refseq:NP_004414.3|dip:DIP-34509N|ensembl:ENSG00000161202(gene)|ensembl:ENST00000313143(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002020"(protease binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005109"(frizzled binding)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0038031"(non-canonical Wnt signaling pathway via JNK cascade)|go:"GO:0042493"|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050821"(protein stabilization)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0150012"(positive regulation of neuron projection arborization)|go:"GO:1903827"|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008342(Dishevelled-3 protein, C-terminal)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:Q92997|rcsb pdb:6V7O|rcsb pdb:6ZC6|rcsb pdb:6ZC8|reactome:R-HSA-201681|reactome:R-HSA-201688|reactome:R-HSA-4086400|reactome:R-HSA-4641258|reactome:R-HSA-4641262|reactome:R-HSA-5368598|reactome:R-HSA-5663220|reactome:R-HSA-9673324	-	crc64:F26903A4814091C4	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:eA38S7UNOpP716XSQ0zzhYm2TqA559292	rogid:yJ3YIp5IhvKTQwa3bK5yTjNyqXk9606	intact-crc:6376C7BEA4A6612B|rigid:VeX5lQL9qHsDTykQ7ACrwGxW3y0	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q93062-3	uniprotkb:P35184	intact:EBI-740343|ensembl:ENSP00000340176	intact:EBI-17971|uniprotkb:D6VVU2|ensemblfungi:YIR012W	psi-mi:q93062-3(display_long)|uniprotkb:RBPMS(gene name)|psi-mi:RBPMS(display_short)|uniprotkb:HERMES(gene name synonym)|uniprotkb:Heart and RRM expressed sequence(gene name synonym)	psi-mi:sqt1_yeast(display_long)|uniprotkb:YIB12W(orf name)|uniprotkb:YIR012W(locus name)|uniprotkb:SQT1(gene name)|psi-mi:SQT1(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553140|imex:IM-24995-3856	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-740322(rbpms_human)|uniprotkb:Q93062-3(isoform-parent)|ensembl:ENSG00000157110(gene)|ensembl:ENST00000339877(transcript)	refseq:NP_012277.1|sgd:S000001451|ensemblfungi:YIR012W_mRNA(transcript)|ensemblfungi:YIR012W(gene)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|rcsb pdb:4ZOV|rcsb pdb:4ZOX|rcsb pdb:5AMS|dip:DIP-2508N|mint:P35184	-	-	crc64:981D566076B0C881	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:nlPMQAJoKEbPYBwsL3xodmCKd7c9606	rogid:u/Q5uAjR85ZD3op0nHiN20IVCLY559292	intact-crc:666A1735B9FAC088|rigid:RFJo/2SQSQpoKxOsKkKuJxcY/ow	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q93062-3	uniprotkb:P38340	intact:EBI-740343|ensembl:ENSP00000340176	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:q93062-3(display_long)|uniprotkb:RBPMS(gene name)|psi-mi:RBPMS(display_short)|uniprotkb:HERMES(gene name synonym)|uniprotkb:Heart and RRM expressed sequence(gene name synonym)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553136|imex:IM-24995-3855	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-740322(rbpms_human)|uniprotkb:Q93062-3(isoform-parent)|ensembl:ENSG00000157110(gene)|ensembl:ENST00000339877(transcript)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F	-	-	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:nlPMQAJoKEbPYBwsL3xodmCKd7c9606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:A6C7F853820E02F8|rigid:jAPBmauEX7JrUhtS3lKietn4MpQ	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P25566	uniprotkb:Q93062-3	intact:EBI-21713|uniprotkb:D6VQY2|ensemblfungi:YCL033C	intact:EBI-740343|ensembl:ENSP00000340176	psi-mi:mxr2_yeast(display_long)|uniprotkb:YCL033C(locus name)|uniprotkb:YCL33C(orf name)|uniprotkb:MXR2(gene name)|psi-mi:MXR2(display_short)|uniprotkb:MSRB(gene name synonym)	psi-mi:q93062-3(display_long)|uniprotkb:RBPMS(gene name)|psi-mi:RBPMS(display_short)|uniprotkb:HERMES(gene name synonym)|uniprotkb:Heart and RRM expressed sequence(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553120|imex:IM-24995-3851	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009897.1|sgd:S000000538|dip:DIP-4861N|ensemblfungi:YCL033C(gene)|ensemblfungi:YCL033C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0030091"(protein repair)|go:"GO:0033743"("peptide-methionine (R)-S-oxide reductase activity")|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0046872"(metal ion binding)|interpro:IPR002579(Methionine sulphoxide reductase B)|interpro:IPR011057(Mss4-like)|interpro:IPR028427	intact:EBI-740322(rbpms_human)|uniprotkb:Q93062-3(isoform-parent)|ensembl:ENSG00000157110(gene)|ensembl:ENST00000339877(transcript)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:iqa3p6vw9Ah3pxugESw1TdFd6bU559292	rogid:nlPMQAJoKEbPYBwsL3xodmCKd7c9606	intact-crc:C9DBB4ACA2BFC1C4|rigid:tiFI/MCyj+mCRyIppJ+RuLF762E	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P40473	uniprotkb:Q93062-3	intact:EBI-25207|uniprotkb:D6VVG5|ensemblfungi:YIL122W	intact:EBI-740343|ensembl:ENSP00000340176	psi-mi:pog1_yeast(display_long)|uniprotkb:YIL122W(locus name)|uniprotkb:POG1(gene name)|psi-mi:POG1(display_short)|uniprotkb:Promoter of growth protein 1(gene name synonym)	psi-mi:q93062-3(display_long)|uniprotkb:RBPMS(gene name)|psi-mi:RBPMS(display_short)|uniprotkb:HERMES(gene name synonym)|uniprotkb:Heart and RRM expressed sequence(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553128|imex:IM-24995-3853	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000001384|refseq:NP_012144.1|dip:DIP-2755N|ensemblfungi:YIL122W(gene)|ensemblfungi:YIL122W_mRNA(transcript)|go:"GO:0000321"(re-entry into mitotic cell cycle after pheromone arrest)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051301"(cell division)	intact:EBI-740322(rbpms_human)|uniprotkb:Q93062-3(isoform-parent)|ensembl:ENSG00000157110(gene)|ensembl:ENST00000339877(transcript)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:SL7E0QbXBSeu+JDSQhp7p5rNb8M559292	rogid:nlPMQAJoKEbPYBwsL3xodmCKd7c9606	intact-crc:57B6BF25CE0BB874|rigid:LTfvaqT0gfP+tA02L0anJ8XFQLM	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P40956	uniprotkb:Q93062-3	intact:EBI-7968|uniprotkb:D6VTX2|ensemblfungi:YGL181W	intact:EBI-740343|ensembl:ENSP00000340176	psi-mi:gts1_yeast(display_long)|uniprotkb:YGL181W(locus name)|uniprotkb:GTS1(gene name)|psi-mi:GTS1(display_short)|uniprotkb:LSR1(gene name synonym)|uniprotkb:Protein LSR1(gene name synonym)	psi-mi:q93062-3(display_long)|uniprotkb:RBPMS(gene name)|psi-mi:RBPMS(display_short)|uniprotkb:HERMES(gene name synonym)|uniprotkb:Heart and RRM expressed sequence(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553124|imex:IM-24995-3852	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011334.1|sgd:S000003149|mint:P40956|dip:DIP-2746N|ensemblfungi:YGL181W(gene)|ensemblfungi:YGL181W_mRNA(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0006897"(endocytosis)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010512"(negative regulation of phosphatidylinositol biosynthetic process)|go:"GO:0030479"(actin cortical patch)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR037278|interpro:IPR038508	intact:EBI-740322(rbpms_human)|uniprotkb:Q93062-3(isoform-parent)|ensembl:ENSG00000157110(gene)|ensembl:ENST00000339877(transcript)	-	crc64:D687E3BF6B620795	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:8kgpssCRrHiTHsFaOH2nDK6EIjk559292	rogid:nlPMQAJoKEbPYBwsL3xodmCKd7c9606	intact-crc:29C355CE1DA41419|rigid:l+njoww6eYylGUddB6RVXgcNerY	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q93062-3	uniprotkb:Q04307	intact:EBI-740343|ensembl:ENSP00000340176	intact:EBI-15858|uniprotkb:Q2VQW5|ensemblfungi:YDR045C|uniprotkb:D6VS33	psi-mi:q93062-3(display_long)|uniprotkb:RBPMS(gene name)|psi-mi:RBPMS(display_short)|uniprotkb:HERMES(gene name synonym)|uniprotkb:Heart and RRM expressed sequence(gene name synonym)	psi-mi:rpc10_yeast(display_long)|uniprotkb:RPC11(gene name)|psi-mi:RPC11(display_short)|uniprotkb:YDR045C(locus name)|uniprotkb:YD9609.01C(orf name)|uniprotkb:RNA polymerase III subunit C11(gene name synonym)|uniprotkb:DNA-directed RNA polymerases III 12.5 kDa polypeptide(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553132|imex:IM-24995-3854	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-740322(rbpms_human)|uniprotkb:Q93062-3(isoform-parent)|ensembl:ENSG00000157110(gene)|ensembl:ENST00000339877(transcript)	ensemblfungi:YDR045C(gene)|refseq:NP_010330.1|sgd:S000002452|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006386"(termination of RNA polymerase III transcription)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042779"(tRNA 3'-trailer cleavage)|go:"GO:0042797"(tRNA transcription by RNA polymerase III)|interpro:IPR001222(Zinc finger, TFIIS-type)|interpro:IPR001529(DNA-directed RNA polymerase, M/15 kDa subunit)|interpro:IPR012164(DNA-directed RNA polymerase, subunit C11/M/9)|interpro:IPR019761|interpro:IPR034014|rcsb pdb:3QT1|ensemblfungi:YDR045C_mRNA(transcript)|rcsb pdb:5FJ8|rcsb pdb:5FJ9|rcsb pdb:5FJA|rcsb pdb:6CNB|rcsb pdb:6CNC|rcsb pdb:6CND|rcsb pdb:6CNF|rcsb pdb:6EU0|rcsb pdb:6EU2|rcsb pdb:6EU3|rcsb pdb:6F40|rcsb pdb:6F41|rcsb pdb:6F42|rcsb pdb:6F44|rcsb pdb:6TUT|reactome:R-SCE-76061|reactome:R-SCE-76066|rcsb pdb:6EU1|dip:DIP-887N|mint:Q04307	-	-	crc64:E4AA802EC9F92230	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:nlPMQAJoKEbPYBwsL3xodmCKd7c9606	rogid:G2fIQbptabHIUI224iPtTJF+dIs559292	intact-crc:CE1E197DE928C19E|rigid:ivhDb+JqObLZCtlrAtGVpM86ook	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P15365	uniprotkb:Q969F0	intact:EBI-5527|uniprotkb:D6VWX1|ensemblfungi:YJR152W	intact:EBI-743099|ensembl:ENSP00000359375	psi-mi:dal5_yeast(display_long)|uniprotkb:DAL5(gene name)|psi-mi:DAL5(display_short)|uniprotkb:UREP1(gene name synonym)|uniprotkb:YJR152W(locus name)|uniprotkb:J2230(orf name)	psi-mi:fate1_human(display_long)|uniprotkb:Tumor antigen BJ-HCC-2(gene name synonym)|uniprotkb:Cancer/testis antigen 43(gene name synonym)|uniprotkb:FATE1(gene name)|psi-mi:FATE1(display_short)|uniprotkb:FATE(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553164|imex:IM-24995-3862	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003913|refseq:NP_012686.3|dip:DIP-7873N|mint:P15365|ensemblfungi:YJR152W(gene)|ensemblfungi:YJR152W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0015124"(allantoate transmembrane transporter activity)|go:"GO:0015719"(allantoate transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0031224"(intrinsic component of membrane)|go:"GO:0042938"(dipeptide transport)|go:"GO:0042939"(tripeptide transport)|go:"GO:0071916"(dipeptide transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR036259	refseq:NP_149076.1|ensembl:ENSG00000147378(gene)|ensembl:ENST00000370350(transcript)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|go:"GO:0051562"(negative regulation of mitochondrial calcium ion concentration)|interpro:IPR039153|interpro:IPR039433|mint:Q969F0	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Y2kCv3dK4Hjn9hJpK+WK5rp6VKU559292	rogid:Nm1N6lO92MHr5rIKC007oouF5RE9606	intact-crc:ADB0924756A0E514|rigid:RD0RDUauwGS/643juHawjhQo/4A	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
intact:EBI-11522506	uniprotkb:Q969F0	-	intact:EBI-743099|ensembl:ENSP00000359375	psi-mi:mps3(display_short)|psi-mi:EBI-11522506(display_long)	psi-mi:fate1_human(display_long)|uniprotkb:Tumor antigen BJ-HCC-2(gene name synonym)|uniprotkb:Cancer/testis antigen 43(gene name synonym)|uniprotkb:FATE1(gene name)|psi-mi:FATE1(display_short)|uniprotkb:FATE(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553160|imex:IM-24995-3861	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	-	refseq:NP_149076.1|ensembl:ENSG00000147378(gene)|ensembl:ENST00000370350(transcript)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|go:"GO:0051562"(negative regulation of mitochondrial calcium ion concentration)|interpro:IPR039153|interpro:IPR039433|mint:Q969F0	-	no-uniprot-update:	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:L0dsobyr9SpxA4nDPBr9V2OBaqU4932	rogid:Nm1N6lO92MHr5rIKC007oouF5RE9606	intact-crc:C7BE7FE55DFD8DC7|rigid:2wk6m3/qprPOZIJ4MLIY5UEXyU0	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q93062-3	uniprotkb:Q8TGQ8	intact:EBI-740343|ensembl:ENSP00000340176	intact:EBI-11537679|ensemblfungi:YOL085W-A	psi-mi:q93062-3(display_long)|uniprotkb:RBPMS(gene name)|psi-mi:RBPMS(display_short)|uniprotkb:HERMES(gene name synonym)|uniprotkb:Heart and RRM expressed sequence(gene name synonym)	psi-mi:yo85a_yeast(display_long)|uniprotkb:YOL085W-A(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553144|imex:IM-24995-3857	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-740322(rbpms_human)|uniprotkb:Q93062-3(isoform-parent)|ensembl:ENSG00000157110(gene)|ensembl:ENST00000339877(transcript)	sgd:S000028708|ensemblfungi:YOL085W-A(gene)|ensemblfungi:YOL085W-A_mRNA(transcript)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/03/16	rogid:nlPMQAJoKEbPYBwsL3xodmCKd7c9606	rogid:kZcPWq9185AwxM/LykJ1Bui6Hvs559292	intact-crc:65BE8817648A050E|rigid:l4nCtVQGgG4GhFhdK1AAtRyBsHA	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q12484	uniprotkb:Q93062-3	intact:EBI-29987|uniprotkb:A0A1S0T0C0|ensemblfungi:YOR343C	intact:EBI-740343|ensembl:ENSP00000340176	psi-mi:yo343_yeast(display_long)|uniprotkb:O6287(orf name)|uniprotkb:YOR343C(locus name)	psi-mi:q93062-3(display_long)|uniprotkb:RBPMS(gene name)|psi-mi:RBPMS(display_short)|uniprotkb:HERMES(gene name synonym)|uniprotkb:Heart and RRM expressed sequence(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553152|imex:IM-24995-3859	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005870|ensemblfungi:YOR343C(gene)|ensemblfungi:YOR343C_mRNA(transcript)	intact:EBI-740322(rbpms_human)|uniprotkb:Q93062-3(isoform-parent)|ensembl:ENSG00000157110(gene)|ensembl:ENST00000339877(transcript)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:ULgWWTa6oS2393jSgXiCDeyIVlo559292	rogid:nlPMQAJoKEbPYBwsL3xodmCKd7c9606	intact-crc:18411E2801FF510D|rigid:dP4sHialG+KA7qhUhJS0Z/89y2s	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q03020	uniprotkb:Q93062-3	intact:EBI-29901|uniprotkb:D6W3N2|ensemblfungi:YPL135W	intact:EBI-740343|ensembl:ENSP00000340176	psi-mi:isu1_yeast(display_long)|uniprotkb:YPL135W(locus name)|uniprotkb:Iron sulfur cluster scaffold protein 1(gene name synonym)|uniprotkb:ISU1(gene name)|psi-mi:ISU1(display_short)|uniprotkb:NUA1(gene name synonym)	psi-mi:q93062-3(display_long)|uniprotkb:RBPMS(gene name)|psi-mi:RBPMS(display_short)|uniprotkb:HERMES(gene name synonym)|uniprotkb:Heart and RRM expressed sequence(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553148|imex:IM-24995-3858	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015190.1|sgd:S000006056|dip:DIP-6556N|mint:Q03020|ensemblfungi:YPL135W(gene)|ensemblfungi:YPL135W_mRNA(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005506"(iron ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR002871(NIF system FeS cluster assembly, NifU, N-terminal)|interpro:IPR011339(ISC system FeS cluster assembly, IscU scaffold)|rcsb pdb:5T0V|rcsb pdb:5TRE|reactome:R-SCE-1362409	intact:EBI-740322(rbpms_human)|uniprotkb:Q93062-3(isoform-parent)|ensembl:ENSG00000157110(gene)|ensembl:ENST00000339877(transcript)	-	crc64:E240845A27D2E9EE	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:zpPseOgZoK3cF+mCetzw05ct9Kc559292	rogid:nlPMQAJoKEbPYBwsL3xodmCKd7c9606	intact-crc:2F5CEE921D3A3300|rigid:p2Ku2KyhTX79IL6qo7CX0bDyGDc	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P32902	uniprotkb:Q93062-3	intact:EBI-16248|ensemblfungi:YHL004W|uniprotkb:D3DKR0	intact:EBI-740343|ensembl:ENSP00000340176	psi-mi:rt04_yeast(display_long)|uniprotkb:MRP4(gene name)|psi-mi:MRP4(display_short)|uniprotkb:MRP4A(gene name synonym)|uniprotkb:Mitochondrial small ribosomal subunit protein uS2m(gene name synonym)|uniprotkb:YHL004W(locus name)	psi-mi:q93062-3(display_long)|uniprotkb:RBPMS(gene name)|psi-mi:RBPMS(display_short)|uniprotkb:HERMES(gene name synonym)|uniprotkb:Heart and RRM expressed sequence(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553156|imex:IM-24995-3860	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YHL004W(gene)|ensemblfungi:YHL004W_mRNA(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR001865(Ribosomal protein S2)|interpro:IPR005706(Ribosomal protein S2, bacterial-type)|interpro:IPR018130|interpro:IPR023591|rcsb pdb:5MRC|rcsb pdb:5MRE|rcsb pdb:5MRF|refseq:NP_011859.1|sgd:S000000996|dip:DIP-5035N|mint:P32902	intact:EBI-740322(rbpms_human)|uniprotkb:Q93062-3(isoform-parent)|ensembl:ENSG00000157110(gene)|ensembl:ENST00000339877(transcript)	-	crc64:81A1CB33134BC559	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:BlL3W6HUN+uAKF/AxwlV1zT5YZQ559292	rogid:nlPMQAJoKEbPYBwsL3xodmCKd7c9606	intact-crc:D5A6E5C0A09AA64A|rigid:mOQLEyFM/aDCReQLyjzL2d09iKY	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P53262	uniprotkb:Q969F0	intact:EBI-2061527|uniprotkb:D6VUN8|ensemblfungi:YGR106C	intact:EBI-743099|ensembl:ENSP00000359375	psi-mi:voa1_yeast(display_long)|uniprotkb:YGR106C(locus name)|uniprotkb:VOA1(gene name)|psi-mi:VOA1(display_short)	psi-mi:fate1_human(display_long)|uniprotkb:Tumor antigen BJ-HCC-2(gene name synonym)|uniprotkb:Cancer/testis antigen 43(gene name synonym)|uniprotkb:FATE1(gene name)|psi-mi:FATE1(display_short)|uniprotkb:FATE(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553184|imex:IM-24995-3867	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003338|refseq:NP_011620.1|mint:P53262|ensemblfungi:YGR106C(gene)|ensemblfungi:YGR106C_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034622"|rcsb pdb:6C6L|rcsb pdb:6M0R|rcsb pdb:6M0S|rcsb pdb:6O7T|rcsb pdb:6O7U|rcsb pdb:6O7V|rcsb pdb:6O7W|rcsb pdb:6O7X|rcsb pdb:6PE4|rcsb pdb:6PE5	refseq:NP_149076.1|ensembl:ENSG00000147378(gene)|ensembl:ENST00000370350(transcript)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|go:"GO:0051562"(negative regulation of mitochondrial calcium ion concentration)|interpro:IPR039153|interpro:IPR039433|mint:Q969F0	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:lKLIonttSEX36IQaIKlzxS/Cdxg559292	rogid:Nm1N6lO92MHr5rIKC007oouF5RE9606	intact-crc:18007C06B0542B14|rigid:TrqFIPTlPqsUo/Q5JllfF0BXvLI	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q08144	uniprotkb:Q969F0	intact:EBI-19302|uniprotkb:D6W248|uniprotkb:E9P933|ensemblfungi:YOL018C	intact:EBI-743099|ensembl:ENSP00000359375	psi-mi:tlg2_yeast(display_long)|uniprotkb:YOL018C(locus name)|uniprotkb:TLG2(gene name)|psi-mi:TLG2(display_short)|uniprotkb:Syntaxin TLG2(gene name synonym)	psi-mi:fate1_human(display_long)|uniprotkb:Tumor antigen BJ-HCC-2(gene name synonym)|uniprotkb:Cancer/testis antigen 43(gene name synonym)|uniprotkb:FATE1(gene name)|psi-mi:FATE1(display_short)|uniprotkb:FATE(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553180|imex:IM-24995-3866	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014624.1|sgd:S000005378|ensemblfungi:YOL018C(gene)|ensemblfungi:YOL018C_mRNA(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006673"(inositol phosphoceramide metabolic process)|go:"GO:0006675"(mannosyl-inositol phosphorylceramide metabolic process)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0031303"(integral component of endosome membrane)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0032527"(protein exit from endoplasmic reticulum)|go:"GO:0048278"(vesicle docking)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|interpro:IPR028673|reactome:R-SCE-6811440|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0006897"(endocytosis)|go:"GO:0006906"(vesicle fusion)|go:"GO:0009306"(protein secretion)|dip:DIP-4244N|mint:Q08144	refseq:NP_149076.1|ensembl:ENSG00000147378(gene)|ensembl:ENST00000370350(transcript)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|go:"GO:0051562"(negative regulation of mitochondrial calcium ion concentration)|interpro:IPR039153|interpro:IPR039433|mint:Q969F0	-	crc64:CEBD6FE11278B1F0	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:M7Ezt/D1lvPf/T8TrjQwtKNhFhw559292	rogid:Nm1N6lO92MHr5rIKC007oouF5RE9606	intact-crc:AD422C6C24EDC22E|rigid:cQACnOQCbuaL/pzJ2LBnjJi+ikM	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q12006	uniprotkb:Q969F0	intact:EBI-36378|uniprotkb:D6W264|ensemblfungi:YOL003C	intact:EBI-743099|ensembl:ENSP00000359375	psi-mi:pfa4_yeast(display_long)|uniprotkb:PFA4(gene name)|psi-mi:PFA4(display_short)|uniprotkb:UNE378(orf name)|uniprotkb:Protein fatty acyltransferase 4(gene name synonym)|uniprotkb:YOL003C(locus name)|uniprotkb:Protein S-acyltransferase(gene name synonym)	psi-mi:fate1_human(display_long)|uniprotkb:Tumor antigen BJ-HCC-2(gene name synonym)|uniprotkb:Cancer/testis antigen 43(gene name synonym)|uniprotkb:FATE1(gene name)|psi-mi:FATE1(display_short)|uniprotkb:FATE(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553168|imex:IM-24995-3863	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014640.1|sgd:S000005363|dip:DIP-4248N|reactome:R-SCE-203615|ensemblfungi:YOL003C(gene)|ensemblfungi:YOL003C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR033682	refseq:NP_149076.1|ensembl:ENSG00000147378(gene)|ensembl:ENST00000370350(transcript)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|go:"GO:0051562"(negative regulation of mitochondrial calcium ion concentration)|interpro:IPR039153|interpro:IPR039433|mint:Q969F0	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:yzNswK8Xpbra0kf0p0cRh+CXCqo559292	rogid:Nm1N6lO92MHr5rIKC007oouF5RE9606	intact-crc:967DC15C1EDCE1A7|rigid:3rCoXocZsVRHENUsM9wJMEg03BE	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P38340	uniprotkb:Q969F0	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-743099|ensembl:ENSP00000359375	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:fate1_human(display_long)|uniprotkb:Tumor antigen BJ-HCC-2(gene name synonym)|uniprotkb:Cancer/testis antigen 43(gene name synonym)|uniprotkb:FATE1(gene name)|psi-mi:FATE1(display_short)|uniprotkb:FATE(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553172|imex:IM-24995-3864	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F	refseq:NP_149076.1|ensembl:ENSG00000147378(gene)|ensembl:ENST00000370350(transcript)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|go:"GO:0051562"(negative regulation of mitochondrial calcium ion concentration)|interpro:IPR039153|interpro:IPR039433|mint:Q969F0	-	crc64:66699F37B0013088	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:Nm1N6lO92MHr5rIKC007oouF5RE9606	intact-crc:FA829E4B0DEEE020|rigid:/+zc1OuYwsGDsNuo4mQd/iw7VIE	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q969F0	uniprotkb:P25656	intact:EBI-743099|ensembl:ENSP00000359375	intact:EBI-22014|uniprotkb:D6VR94|ensemblfungi:YCR094W	psi-mi:fate1_human(display_long)|uniprotkb:Tumor antigen BJ-HCC-2(gene name synonym)|uniprotkb:Cancer/testis antigen 43(gene name synonym)|uniprotkb:FATE1(gene name)|psi-mi:FATE1(display_short)|uniprotkb:FATE(gene name synonym)	psi-mi:cdc50_yeast(display_long)|uniprotkb:YCR94W(orf name)|uniprotkb:YCR094W(locus name)|uniprotkb:CDC50(gene name)|psi-mi:CDC50(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553176|imex:IM-24995-3865	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_149076.1|ensembl:ENSG00000147378(gene)|ensembl:ENST00000370350(transcript)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|go:"GO:0051562"(negative regulation of mitochondrial calcium ion concentration)|interpro:IPR039153|interpro:IPR039433|mint:Q969F0	refseq:NP_010018.1|sgd:S000000690|dip:DIP-5138N|ensemblfungi:YCR094W(gene)|ensemblfungi:YCR094W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006897"(endocytosis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0045332"(phospholipid translocation)|go:"GO:0051666"(actin cortical patch localization)|go:"GO:0140331"(aminophospholipid translocation)|go:"GO:1990530"(Cdc50p-Drs2p complex)|interpro:IPR005045(Protein of unknown function DUF284, transmembrane eukaryotic)|rcsb pdb:6PSY|rcsb pdb:6ROH|rcsb pdb:6ROI|rcsb pdb:6ROJ|rcsb pdb:7OH4|rcsb pdb:7OH6|rcsb pdb:7OH7|reactome:R-SCE-6798695|rcsb pdb:6PSX|mint:P25656	-	-	crc64:565575CA402C0C91	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Nm1N6lO92MHr5rIKC007oouF5RE9606	rogid:zVi09MNh1hpBUuc5AzasxmCrnKY559292	intact-crc:393E57C470384710|rigid:Wvf8VIUEVahkuI+cHqFOqMHyVSU	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P48362	uniprotkb:Q969G2	intact:EBI-8304|uniprotkb:D6VUX0|ensemblfungi:YGR187C	intact:EBI-2865388|uniprotkb:Q8NHM1|uniprotkb:Q969W2|uniprotkb:Q8TCJ1|uniprotkb:Q8NHE0|uniprotkb:Q8WWX2|ensembl:ENSP00000263726	psi-mi:hgh1_yeast(display_long)|uniprotkb:HGH1(gene name)|psi-mi:HGH1(display_short)|uniprotkb:HMG1/2 protein homolog(gene name synonym)|uniprotkb:G7538(orf name)|uniprotkb:YGR187C(locus name)	psi-mi:lhx4_human(display_long)|uniprotkb:LHX4(gene name)|psi-mi:LHX4(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553208|imex:IM-24995-3873	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003419|refseq:NP_011703.3|mint:P48362|dip:DIP-4721N|ensemblfungi:YGR187C(gene)|ensemblfungi:YGR187C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0061770"(translation elongation factor binding)|interpro:IPR007205(Protein of unknown function DUF383)|interpro:IPR007206(Protein of unknown function DUF384)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR039717|rcsb pdb:6HB1|rcsb pdb:6HB2|rcsb pdb:6HB3	refseq:NP_203129.1|dip:DIP-29454N|ensembl:ENSG00000121454(gene)|ensembl:ENST00000263726(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001890"(placenta development)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0021526"(medial motor column neuron differentiation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|mint:Q969G2|rcsb pdb:5HOD|reactome:R-HSA-9010553	-	crc64:24D4EFAEBD5D7A48	crc64:6499F38E78B79FD1	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:YQkKPiBqhycG0Z+2lxERBLVdy1w559292	rogid:dCB3WgIBMdi0nNvaCFaioh+F9sw9606	intact-crc:34D4CD88D468DCC6|rigid:+aolQ+4ablvd2k8Qys4GsTOkhZg	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q06616	uniprotkb:Q969F0	intact:EBI-36065|uniprotkb:D6W4H5|ensemblfungi:YPR174C	intact:EBI-743099|ensembl:ENSP00000359375	psi-mi:yp174_yeast(display_long)|uniprotkb:YPR174C(locus name)	psi-mi:fate1_human(display_long)|uniprotkb:Tumor antigen BJ-HCC-2(gene name synonym)|uniprotkb:Cancer/testis antigen 43(gene name synonym)|uniprotkb:FATE1(gene name)|psi-mi:FATE1(display_short)|uniprotkb:FATE(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553204|imex:IM-24995-3872	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015500.1|sgd:S000006378|dip:DIP-3800N|ensemblfungi:YPR174C(gene)|ensemblfungi:YPR174C_mRNA(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034399"(nuclear periphery)|interpro:IPR013743(Nap binding NBP1, fungi)	refseq:NP_149076.1|ensembl:ENSG00000147378(gene)|ensembl:ENST00000370350(transcript)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|go:"GO:0051562"(negative regulation of mitochondrial calcium ion concentration)|interpro:IPR039153|interpro:IPR039433|mint:Q969F0	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:R+7auDlEsOm+VR9gJ1jZsF3ST88559292	rogid:Nm1N6lO92MHr5rIKC007oouF5RE9606	intact-crc:0BDFDAC1DD988183|rigid:Lk+btTFjqrWeHn5nH/Yl1jEACt8	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q969F0	uniprotkb:P54074	intact:EBI-743099|ensembl:ENSP00000359375	intact:EBI-27241|uniprotkb:D6VZU2|ensemblfungi:YMR119W	psi-mi:fate1_human(display_long)|uniprotkb:Tumor antigen BJ-HCC-2(gene name synonym)|uniprotkb:Cancer/testis antigen 43(gene name synonym)|uniprotkb:FATE1(gene name)|psi-mi:FATE1(display_short)|uniprotkb:FATE(gene name synonym)	psi-mi:asi1_yeast(display_long)|uniprotkb:YMR119W(locus name)|uniprotkb:YM9718.18(orf name)|uniprotkb:YM8564.01(orf name)|uniprotkb:Amino acid sensor-independent protein 1(gene name synonym)|uniprotkb:ASI1(gene name)|psi-mi:ASI1(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553188|imex:IM-24995-3868	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_149076.1|ensembl:ENSG00000147378(gene)|ensembl:ENST00000370350(transcript)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|go:"GO:0051562"(negative regulation of mitochondrial calcium ion concentration)|interpro:IPR039153|interpro:IPR039433|mint:Q969F0	refseq:NP_013837.1|sgd:S000004725|dip:DIP-7733N|ensemblfungi:YMR119W(gene)|ensemblfungi:YMR119W_mRNA(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034399"(nuclear periphery)|go:"GO:0036369"(transcription factor catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0097658"(Asi complex)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Nm1N6lO92MHr5rIKC007oouF5RE9606	rogid:CvH0AkCWby1t6LwuYC0K/dI2jgo559292	intact-crc:450F2FF3D3C5A1C3|rigid:9yTvzpIj8pynG9tcp0PMLW1HC3U	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P25353	uniprotkb:Q969F0	intact:EBI-3691762|uniprotkb:D6VR36|uniprotkb:Q8NIL9|ensemblfungi:YCR026C	intact:EBI-743099|ensembl:ENSP00000359375	psi-mi:npp1_yeast(display_long)|uniprotkb:NPP1(gene name)|psi-mi:NPP1(display_short)|uniprotkb:YCR26C(orf name)|uniprotkb:YCR246(orf name)|uniprotkb:YCR026C(locus name)	psi-mi:fate1_human(display_long)|uniprotkb:Tumor antigen BJ-HCC-2(gene name synonym)|uniprotkb:Cancer/testis antigen 43(gene name synonym)|uniprotkb:FATE1(gene name)|psi-mi:FATE1(display_short)|uniprotkb:FATE(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553196|imex:IM-24995-3870	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009955.2|sgd:S000000621|interpro:IPR017850(Alkaline-phosphatase-like, core domain)|interpro:IPR002591(Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase)|reactome:R-SCE-1660662|reactome:R-SCE-6814848|ensemblfungi:YCR026C(gene)|ensemblfungi:YCR026C_mRNA(transcript)|go:"GO:0004528"(phosphodiesterase I activity)|go:"GO:0009141"(nucleoside triphosphate metabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016036"(cellular response to phosphate starvation)|go:"GO:0017111"(nucleoside-triphosphatase activity)|go:"GO:0035529"(NADH pyrophosphatase activity)|go:"GO:0036218"(dTTP diphosphatase activity)|go:"GO:0047429"(nucleoside-triphosphate diphosphatase activity)|reactome:R-SCE-196843|reactome:R-SCE-6798695	refseq:NP_149076.1|ensembl:ENSG00000147378(gene)|ensembl:ENST00000370350(transcript)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|go:"GO:0051562"(negative regulation of mitochondrial calcium ion concentration)|interpro:IPR039153|interpro:IPR039433|mint:Q969F0	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:eudbgXN3Y6QR2ebTYl+l1JoNuG0559292	rogid:Nm1N6lO92MHr5rIKC007oouF5RE9606	intact-crc:F8F6181A8515D521|rigid:iOSqFRP5udaWXmqwEmtaFlHj9jM	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q969F0	uniprotkb:A0A6L1C4M5	intact:EBI-743099|ensembl:ENSP00000359375	intact:EBI-11522494	psi-mi:fate1_human(display_long)|uniprotkb:Tumor antigen BJ-HCC-2(gene name synonym)|uniprotkb:Cancer/testis antigen 43(gene name synonym)|uniprotkb:FATE1(gene name)|psi-mi:FATE1(display_short)|uniprotkb:FATE(gene name synonym)	psi-mi:a0a6l1c4m5_yeasx(display_long)|uniprotkb:PACBIOSEQ_LOCUS6219(orf name)|uniprotkb:PACBIOSEQ_LOCUS6225(orf name)|uniprotkb:PACBIOSEQ_LOCUS6235(orf name)|uniprotkb:PACBIOSEQ_LOCUS6264(orf name)|uniprotkb:PACBIOSEQ_LOCUS6286(orf name)|uniprotkb:PACBIOSEQ_LOCUS6327(orf name)|uniprotkb:SCNYR20_0005038000(orf name)|uniprotkb:SCP684_0005037600(orf name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553192|imex:IM-24995-3869	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_149076.1|ensembl:ENSG00000147378(gene)|ensembl:ENST00000370350(transcript)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|go:"GO:0051562"(negative regulation of mitochondrial calcium ion concentration)|interpro:IPR039153|interpro:IPR039433|mint:Q969F0	go:"GO:0016021"(integral component of membrane)|uniprotkb:A0A250WEI1(uniprot-removed-ac)|interpro:IPR019334	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:Nm1N6lO92MHr5rIKC007oouF5RE9606	rogid:SRq+kqkRupgoOO2oywFAv0D2VGc4932	intact-crc:2CD2B75B8A386F44|rigid:q8MR7lCVVaclXUxjJkQXOdptm2w	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P52870	uniprotkb:Q969F0	intact:EBI-16410|ensemblfungi:YER087C-B|uniprotkb:D3DLZ4	intact:EBI-743099|ensembl:ENSP00000359375	psi-mi:sc6b1_yeast(display_long)|uniprotkb:Sec61 complex subunit SBH1(gene name synonym)|uniprotkb:YER087BC(orf name)|uniprotkb:YER087C-B(locus name)|uniprotkb:SBH1(gene name)|psi-mi:SBH1(display_short)|uniprotkb:SEB1(gene name synonym)|uniprotkb:Sec61 complex subunit beta(gene name synonym)	psi-mi:fate1_human(display_long)|uniprotkb:Tumor antigen BJ-HCC-2(gene name synonym)|uniprotkb:Cancer/testis antigen 43(gene name synonym)|uniprotkb:FATE1(gene name)|psi-mi:FATE1(display_short)|uniprotkb:FATE(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553200|imex:IM-24995-3871	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YER087C-B(gene)|ensemblfungi:YER087C-B_mRNA(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|interpro:IPR016482(Preprotein translocase Sec, Sec61-beta subunit, eukarya)|interpro:IPR030671|rcsb pdb:6N3Q|rcsb pdb:6ND1|rcsb pdb:7AFT|rcsb pdb:7KAH|rcsb pdb:7KAI|sgd:S000002128|rcsb pdb:7KAJ|rcsb pdb:7KAO|rcsb pdb:7KAP|rcsb pdb:7KAQ|rcsb pdb:7KAR|rcsb pdb:7KAS|rcsb pdb:7KAT|rcsb pdb:7KAU|rcsb pdb:7KB5|refseq:NP_011011.3|dip:DIP-5681N|mint:P52870	refseq:NP_149076.1|ensembl:ENSG00000147378(gene)|ensembl:ENST00000370350(transcript)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|go:"GO:0051562"(negative regulation of mitochondrial calcium ion concentration)|interpro:IPR039153|interpro:IPR039433|mint:Q969F0	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:9cYnDPhmMpAOdB2GV5TxikzpjI0559292	rogid:Nm1N6lO92MHr5rIKC007oouF5RE9606	intact-crc:F7C823D5F33A0395|rigid:c0v+1AqiLG1L7oPfiRG1Ud9D9w8	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q12161	uniprotkb:Q969J2	intact:EBI-34372|uniprotkb:D6W213|ensemblfungi:YOL054W	intact:EBI-2818641|uniprotkb:B2RE32|uniprotkb:Q5U7L4|intact:EBI-28979011|ensembl:ENSP00000366509	psi-mi:psh1_yeast(display_long)|uniprotkb:PSH1(gene name)|psi-mi:PSH1(display_short)|uniprotkb:POB3/SPT16 histone-associated protein 1(gene name synonym)|uniprotkb:O1263(orf name)|uniprotkb:YOL054W(locus name)	psi-mi:zksc4_human(display_long)|uniprotkb:ZKSCAN4(gene name)|psi-mi:ZKSCAN4(display_short)|uniprotkb:ZNF307(gene name synonym)|uniprotkb:ZNF427(gene name synonym)|uniprotkb:P373c6.1(gene name synonym)|uniprotkb:Zinc finger protein 307(gene name synonym)|uniprotkb:Zinc finger protein 427(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553224|imex:IM-24995-3877	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014587.1|sgd:S000005415|mint:Q12161|dip:DIP-6481N|ensemblfungi:YOL054W(gene)|ensemblfungi:YOL054W_mRNA(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907	refseq:NP_061983.2|ensembl:ENSP00000366509|ensembl:ENSG00000187626(gene)|ensembl:ENST00000377294(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|interpro:IPR038269|mint:Q969J2|reactome:R-HSA-212436|refseq:XP_005249152.1	-	crc64:CE0ECBCB6D465554	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:AvPMRd/GjfaTyQjEfMPhBVcvOs4559292	rogid:5TWhAtzfmCXHkOSbjKwjgLIsCcs9606	intact-crc:ED2432DD25B12A3C|rigid:WiqvZDzvfklS89IxQr5U6KY8I3U	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P36001	uniprotkb:Q969G2	intact:EBI-2083615|uniprotkb:D6VX64|ensemblfungi:YKL132C	intact:EBI-2865388|uniprotkb:Q8NHM1|uniprotkb:Q969W2|uniprotkb:Q8TCJ1|uniprotkb:Q8NHE0|uniprotkb:Q8WWX2|ensembl:ENSP00000263726	psi-mi:folc_yeast(display_long)|uniprotkb:RMA1(gene name)|psi-mi:RMA1(display_short)|uniprotkb:Folylpoly-gamma-glutamate synthetase(gene name synonym)|uniprotkb:Tetrahydrofolylpolyglutamate synthase(gene name synonym)|uniprotkb:YKL132C(locus name)	psi-mi:lhx4_human(display_long)|uniprotkb:LHX4(gene name)|psi-mi:LHX4(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553212|imex:IM-24995-3874	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012790.1|sgd:S000001615|interpro:IPR001645(Folylpolyglutamate synthetase)|interpro:IPR018109|mint:P36001|interpro:IPR036565|interpro:IPR036615|ensemblfungi:YKL132C(gene)|ensemblfungi:YKL132C_mRNA(transcript)|go:"GO:0004326"(tetrahydrofolylpolyglutamate synthase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0008841"(dihydrofolate synthase activity)|go:"GO:0009396"(folic acid-containing compound biosynthetic process)|go:"GO:0016881"(acid-amino acid ligase activity)|go:"GO:0046872"(metal ion binding)	refseq:NP_203129.1|dip:DIP-29454N|ensembl:ENSG00000121454(gene)|ensembl:ENST00000263726(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001890"(placenta development)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0021526"(medial motor column neuron differentiation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|mint:Q969G2|rcsb pdb:5HOD|reactome:R-HSA-9010553	-	-	crc64:6499F38E78B79FD1	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:pL0jH0sRdb39RE+KmXGMCnXkFZw559292	rogid:dCB3WgIBMdi0nNvaCFaioh+F9sw9606	intact-crc:5D69F78762D2A8C4|rigid:ojXQqv3rN6YPRhA+cjelvDLhNDo	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q969J2	uniprotkb:Q03020	intact:EBI-2818641|uniprotkb:B2RE32|uniprotkb:Q5U7L4|intact:EBI-28979011|ensembl:ENSP00000366509	intact:EBI-29901|uniprotkb:D6W3N2|ensemblfungi:YPL135W	psi-mi:zksc4_human(display_long)|uniprotkb:ZKSCAN4(gene name)|psi-mi:ZKSCAN4(display_short)|uniprotkb:ZNF307(gene name synonym)|uniprotkb:ZNF427(gene name synonym)|uniprotkb:P373c6.1(gene name synonym)|uniprotkb:Zinc finger protein 307(gene name synonym)|uniprotkb:Zinc finger protein 427(gene name synonym)	psi-mi:isu1_yeast(display_long)|uniprotkb:YPL135W(locus name)|uniprotkb:Iron sulfur cluster scaffold protein 1(gene name synonym)|uniprotkb:ISU1(gene name)|psi-mi:ISU1(display_short)|uniprotkb:NUA1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553216|imex:IM-24995-3875	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_061983.2|ensembl:ENSP00000366509|ensembl:ENSG00000187626(gene)|ensembl:ENST00000377294(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|interpro:IPR038269|mint:Q969J2|reactome:R-HSA-212436|refseq:XP_005249152.1	refseq:NP_015190.1|sgd:S000006056|dip:DIP-6556N|mint:Q03020|ensemblfungi:YPL135W(gene)|ensemblfungi:YPL135W_mRNA(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005506"(iron ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR002871(NIF system FeS cluster assembly, NifU, N-terminal)|interpro:IPR011339(ISC system FeS cluster assembly, IscU scaffold)|rcsb pdb:5T0V|rcsb pdb:5TRE|reactome:R-SCE-1362409	-	-	crc64:E240845A27D2E9EE	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:5TWhAtzfmCXHkOSbjKwjgLIsCcs9606	rogid:zpPseOgZoK3cF+mCetzw05ct9Kc559292	intact-crc:CFCA9250FD77F68B|rigid:oyK6B/NIQxzojwQvcUz5rhG6Ilw	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P37263	uniprotkb:Q969J2	intact:EBI-21659|uniprotkb:D6VR87|ensemblfungi:YCR087C-A	intact:EBI-2818641|uniprotkb:B2RE32|uniprotkb:Q5U7L4|intact:EBI-28979011|ensembl:ENSP00000366509	psi-mi:yc16_yeast(display_long)|uniprotkb:YCRX16C(orf name)|uniprotkb:YCR087C-A(locus name)	psi-mi:zksc4_human(display_long)|uniprotkb:ZKSCAN4(gene name)|psi-mi:ZKSCAN4(display_short)|uniprotkb:ZNF307(gene name synonym)|uniprotkb:ZNF427(gene name synonym)|uniprotkb:P373c6.1(gene name synonym)|uniprotkb:Zinc finger protein 307(gene name synonym)|uniprotkb:Zinc finger protein 427(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553220|imex:IM-24995-3876	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010011.1|sgd:S000007223|mint:P37263|dip:DIP-4536N|ensemblfungi:YCR087C-A(gene)|ensemblfungi:YCR087C-A_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR014898(Zinc finger, C2H2, LYAR-type)|interpro:IPR036236|interpro:IPR039999	refseq:NP_061983.2|ensembl:ENSP00000366509|ensembl:ENSG00000187626(gene)|ensembl:ENST00000377294(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|interpro:IPR038269|mint:Q969J2|reactome:R-HSA-212436|refseq:XP_005249152.1	-	crc64:B5B3B4CA37B82042	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:I7iIzRqPZAKdWQSe/IeGsW0qQcU559292	rogid:5TWhAtzfmCXHkOSbjKwjgLIsCcs9606	intact-crc:CE10734F3181E315|rigid:sgHcAG6ilUhpQfZrKLC6ENwANsc	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P32502	uniprotkb:Q969V4	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	intact:EBI-10180409|uniprotkb:D3DTM7|ensembl:ENSP00000341346	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:tekt1_human(display_long)|uniprotkb:TEKT1(gene name)|psi-mi:TEKT1(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553244|imex:IM-24995-3882	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731	refseq:NP_444515.1|ensembl:ENSG00000167858(gene)|ensembl:ENST00000338694(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0031514"(motile cilium)|go:"GO:0060271"(cilium assembly)|go:"GO:0060294"(cilium movement involved in cell motility)|interpro:IPR000435(Tektin)	-	crc64:A5409FAF1594854C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	rogid:5hh7T1hcmqrmmiOtJTT1OokmPrU9606	intact-crc:02E6F64805C20429|rigid:WCtLXYrTqxxPifGCBEDTzthl8bg	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q969L2	uniprotkb:P32453	intact:EBI-944295|uniprotkb:Q6ZMD9|uniprotkb:B2R520|ensembl:ENSP00000479708	intact:EBI-3306|uniprotkb:D6W0N0|ensemblfungi:YNL315C	psi-mi:mal2_human(display_long)|uniprotkb:MAL2(gene name)|psi-mi:MAL2(display_short)	psi-mi:atp11_yeast(display_long)|uniprotkb:ATP11(gene name)|psi-mi:ATP11(display_short)|uniprotkb:N0357(orf name)|uniprotkb:YNL315C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553240|imex:IM-24995-3881	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_443118.1|ensembl:ENSG00000147676(gene)|ensembl:ENST00000614891(transcript)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019911"(structural constituent of myelin sheath)|go:"GO:0042552"(myelination)|go:"GO:0045056"(transcytosis)|go:"GO:0045121"(membrane raft)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|interpro:IPR008253(Marvel)|interpro:IPR013295("Myelin and lymphocyte (MAL)")|interpro:IPR033240	refseq:NP_014084.1|sgd:S000005259|dip:DIP-3026N|mint:P32453|ensemblfungi:YNL315C(gene)|ensemblfungi:YNL315C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0033615"(mitochondrial proton-transporting ATP synthase complex assembly)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR010591(ATP11)	-	-	crc64:61109AA4D338F2CD	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:7SApzrGTzj8V3GIwkdO0X/z6geg9606	rogid:JsQu6HtKtGqAVhHzaPVc8IMYdqM559292	intact-crc:9562D809B28EB068|rigid:QrHmWBKsB/Y8StsD9Jm3zScI0eY	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q969K4	uniprotkb:P53212	intact:EBI-7223971|uniprotkb:Q71MF1|uniprotkb:D3DNB0|intact:MINT-1193021|uniprotkb:Q6ZNU9|uniprotkb:Q96S63|uniprotkb:Q96S62|ensembl:ENSP00000232744	intact:EBI-23099|uniprotkb:D6VUF6|ensemblfungi:YGR021W	psi-mi:abtb1_human(display_long)|uniprotkb:ABTB1(gene name)|psi-mi:ABTB1(display_short)|uniprotkb:Elongation factor 1A-binding protein(gene name synonym)|uniprotkb:BPOZ(gene name synonym)|uniprotkb:PP2259(orf name)	psi-mi:yg1d_yeast(display_long)|uniprotkb:YGR021W(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553228|imex:IM-24995-3878	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011511515.1|refseq:NP_115937.1|refseq:NP_742024.1|ensembl:ENSG00000114626(gene)|ensembl:ENST00000232744(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR020683|interpro:IPR036770|interpro:IPR044515|refseq:XP_016862776.1	refseq:NP_011535.1|sgd:S000003253|dip:DIP-6261N|mint:P53212|ensemblfungi:YGR021W(gene)|ensemblfungi:YGR021W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|interpro:IPR002876(Protein of unknown function DUF28)|interpro:IPR017856(Integrase, N-terminal zinc-binding domain-like)|interpro:IPR026564|interpro:IPR029072	-	comment:mint|comment:homomint|function:May act as a mediator of the PTEN growth-suppressive signaling pathway. May play a role in developmental processes	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:uWEJ/hAJBiKef/EJSNxP4OsXloM9606	rogid:/lU8xaIM/O6RTUPSlVUuReKFU5E559292	intact-crc:1AF17A596458F3C6|rigid:Wf1QdDYuUkCLAMcjXza8p6ERQG4	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q969L2	uniprotkb:P00431	intact:EBI-944295|uniprotkb:Q6ZMD9|uniprotkb:B2R520|ensembl:ENSP00000479708	intact:EBI-4389|uniprotkb:Q6Q5M9|uniprotkb:D6VXC7|ensemblfungi:YKR066C	psi-mi:mal2_human(display_long)|uniprotkb:MAL2(gene name)|psi-mi:MAL2(display_short)	psi-mi:ccpr_yeast(display_long)|uniprotkb:CCP1(gene name)|psi-mi:CCP1(display_short)|uniprotkb:CCP(gene name synonym)|uniprotkb:CPO(gene name synonym)|uniprotkb:YKR066C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553232|imex:IM-24995-3879	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_443118.1|ensembl:ENSG00000147676(gene)|ensembl:ENST00000614891(transcript)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019911"(structural constituent of myelin sheath)|go:"GO:0042552"(myelination)|go:"GO:0045056"(transcytosis)|go:"GO:0045121"(membrane raft)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|interpro:IPR008253(Marvel)|interpro:IPR013295("Myelin and lymphocyte (MAL)")|interpro:IPR033240	refseq:NP_012992.1|sgd:S000001774|dip:DIP-6251N|ensemblfungi:YKR066C(gene)|ensemblfungi:YKR066C_mRNA(transcript)|go:"GO:0000302"(response to reactive oxygen species)|go:"GO:0004130"(cytochrome-c peroxidase activity)|go:"GO:0004601"(peroxidase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0020037"(heme binding)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0046872"(metal ion binding)|interpro:IPR002016(Haem peroxidase, plant/fungal/bacterial)|interpro:IPR002207(Plant ascorbate peroxidase)|interpro:IPR010255(Haem peroxidase)|interpro:IPR019793|interpro:IPR019794|interpro:IPR044831|rcsb pdb:1A2F|rcsb pdb:1A2G|rcsb pdb:1AA4|rcsb pdb:1AC4|rcsb pdb:1AC8|rcsb pdb:1AEB|rcsb pdb:1AED|rcsb pdb:1AEE|rcsb pdb:1AEF|rcsb pdb:1AEG|rcsb pdb:1AEH|rcsb pdb:1AEJ|rcsb pdb:1AEK|rcsb pdb:1AEM|rcsb pdb:1AEN|rcsb pdb:1AEO|rcsb pdb:1AEQ|rcsb pdb:1AES|rcsb pdb:1AET|rcsb pdb:1AEU|rcsb pdb:1AEV|rcsb pdb:1BEJ|rcsb pdb:1BEK|rcsb pdb:1BEM|rcsb pdb:1BEP|rcsb pdb:1BEQ|rcsb pdb:1BES|rcsb pdb:1BJ9|rcsb pdb:1BVA|rcsb pdb:1CCA|rcsb pdb:1CCB|rcsb pdb:1CCC|rcsb pdb:1CCE|rcsb pdb:1CCG|rcsb pdb:1CCI|rcsb pdb:1CCJ|rcsb pdb:1CCK|rcsb pdb:1CCL|rcsb pdb:1CCP|rcsb pdb:1CMP|rcsb pdb:1CMQ|rcsb pdb:1CMT|rcsb pdb:1CPD|rcsb pdb:1CPE|rcsb pdb:1CPF|rcsb pdb:1CPG|rcsb pdb:1CYF|rcsb pdb:1DCC|rcsb pdb:1DJ1|rcsb pdb:1DJ5|rcsb pdb:1DS4|rcsb pdb:1DSE|rcsb pdb:1DSG|rcsb pdb:1DSO|rcsb pdb:1DSP|rcsb pdb:1EBE|rcsb pdb:1JCI|rcsb pdb:1JDR|rcsb pdb:1KOK|rcsb pdb:1KRJ|rcsb pdb:1KXM|rcsb pdb:1KXN|rcsb pdb:1MK8|rcsb pdb:1MKQ|rcsb pdb:1MKR|rcsb pdb:1ML2|rcsb pdb:1RYC|rcsb pdb:1S6V|rcsb pdb:1S73|rcsb pdb:1SBM|rcsb pdb:1SDQ|rcsb pdb:1SOG|rcsb pdb:1STQ|rcsb pdb:1U74|rcsb pdb:1U75|rcsb pdb:1Z53|rcsb pdb:1ZBY|rcsb pdb:1ZBZ|rcsb pdb:2ANZ|rcsb pdb:2AQD|rcsb pdb:2AS1|rcsb pdb:2AS2|rcsb pdb:2AS3|rcsb pdb:2AS4|rcsb pdb:2AS6|rcsb pdb:2B0Z|rcsb pdb:2B10|rcsb pdb:2B11|rcsb pdb:2B12|rcsb pdb:2BCN|rcsb pdb:2CCP|rcsb pdb:2CEP|rcsb pdb:2CYP|rcsb pdb:2EUN|rcsb pdb:2EUO|rcsb pdb:2EUP|rcsb pdb:2EUQ|rcsb pdb:2EUR|rcsb pdb:2EUS|rcsb pdb:2EUT|rcsb pdb:2EUU|rcsb pdb:2GB8|rcsb pdb:2IA8|rcsb pdb:2ICV|rcsb pdb:2JTI|rcsb pdb:2N18|rcsb pdb:2PCB|rcsb pdb:2PCC|rcsb pdb:2RBT|rcsb pdb:2RBU|rcsb pdb:2RBV|rcsb pdb:2RBW|rcsb pdb:2RBX|rcsb pdb:2RBY|rcsb pdb:2RBZ|rcsb pdb:2RC0|rcsb pdb:2RC1|rcsb pdb:2RC2|rcsb pdb:2V23|rcsb pdb:2V2E|rcsb pdb:2X07|rcsb pdb:2X08|rcsb pdb:2XIL|rcsb pdb:2XJ5|rcsb pdb:2XJ8|rcsb pdb:2Y5A|rcsb pdb:2YCG|rcsb pdb:3CCP|rcsb pdb:3CCX|rcsb pdb:3E2N|rcsb pdb:3E2O|rcsb pdb:3EXB|rcsb pdb:3M23|rcsb pdb:3M25|rcsb pdb:3M26|rcsb pdb:3M27|rcsb pdb:3M28|rcsb pdb:3M29|rcsb pdb:3M2A|rcsb pdb:1CMU|rcsb pdb:3M2B|rcsb pdb:3M2C|rcsb pdb:3M2D|rcsb pdb:3M2E|rcsb pdb:3M2F|rcsb pdb:3M2G|rcsb pdb:3M2H|rcsb pdb:3M2I|rcsb pdb:3R98|rcsb pdb:3R99|rcsb pdb:4A6Z|rcsb pdb:4A71|rcsb pdb:4A78|rcsb pdb:4A7M|rcsb pdb:4CCP|rcsb pdb:4CCX|rcsb pdb:4CVI|rcsb pdb:4CVJ|rcsb pdb:4JB4|rcsb pdb:4NFG|rcsb pdb:4P4Q|rcsb pdb:4XV4|rcsb pdb:4XV5|rcsb pdb:4XV6|rcsb pdb:4XV7|rcsb pdb:4XV8|rcsb pdb:4XVA|rcsb pdb:5CCP|rcsb pdb:5CIB|rcsb pdb:5CIC|rcsb pdb:5CID|rcsb pdb:5CIE|rcsb pdb:5CIF|rcsb pdb:5CIG|rcsb pdb:5CIH|rcsb pdb:5D6M|rcsb pdb:5EJT|rcsb pdb:5EJX|rcsb pdb:6CCP|rcsb pdb:6H08|rcsb pdb:6P41|rcsb pdb:6P42|rcsb pdb:6P43|rcsb pdb:6Y1T|rcsb pdb:6Y2Y|rcsb pdb:7CCP	-	-	crc64:A5D26385DA6F0A0B	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:7SApzrGTzj8V3GIwkdO0X/z6geg9606	rogid:LkPXY1wuYoCFzMQPSsAtXZrRi8w559292	intact-crc:B572EF746163EAAE|rigid:BmiQ9cVqnLWMzah7G4aLQsu7hF4	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P04819	uniprotkb:Q969L2	intact:EBI-5991|uniprotkb:Q12736|uniprotkb:D6VRI7|ensemblfungi:YDL164C	intact:EBI-944295|uniprotkb:Q6ZMD9|uniprotkb:B2R520|ensembl:ENSP00000479708	psi-mi:dnli1_yeast(display_long)|uniprotkb:YDL164C(locus name)|uniprotkb:CDC9(gene name)|psi-mi:CDC9(display_short)|uniprotkb:DNA ligase I(gene name synonym)|uniprotkb:Polydeoxyribonucleotide synthase [ATP] 1(gene name synonym)	psi-mi:mal2_human(display_long)|uniprotkb:MAL2(gene name)|psi-mi:MAL2(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553236|imex:IM-24995-3880	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010117.1|sgd:S000002323|dip:DIP-5630N|mint:P04819|ensemblfungi:YDL164C(gene)|ensemblfungi:YDL164C_mRNA(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003677"(DNA binding)|go:"GO:0003910"("DNA ligase (ATP) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006266"(DNA ligation)|go:"GO:0006273"(lagging strand elongation)|go:"GO:0006284"(base-excision repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0035753"(maintenance of DNA trinucleotide repeats)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:0071897"(DNA biosynthetic process)|go:"GO:1903461"(Okazaki fragment processing involved in mitotic DNA replication)|interpro:IPR000977(ATP-dependent DNA ligase)|interpro:IPR012308(DNA ligase, N-terminal)|interpro:IPR012309(ATP dependent DNA ligase, C-terminal)|interpro:IPR012310(ATP dependent DNA ligase, central)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR016059(ATP-dependent DNA ligase, conserved site)|interpro:IPR036599|rcsb pdb:2OD8|reactome:R-SCE-5358565|reactome:R-SCE-5358606|reactome:R-SCE-6782210|reactome:R-SCE-69183	refseq:NP_443118.1|ensembl:ENSG00000147676(gene)|ensembl:ENST00000614891(transcript)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019911"(structural constituent of myelin sheath)|go:"GO:0042552"(myelination)|go:"GO:0045056"(transcytosis)|go:"GO:0045121"(membrane raft)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|interpro:IPR008253(Marvel)|interpro:IPR013295("Myelin and lymphocyte (MAL)")|interpro:IPR033240	-	crc64:B7C2ECAF5C61CAE7	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:sl00ubCmkTFwW2bznucqEF60I3M559292	rogid:7SApzrGTzj8V3GIwkdO0X/z6geg9606	intact-crc:E2A63883B75A118B|rigid:/Drab1hR2vpQO5x3xAkCFelwpTQ	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96B96	uniprotkb:P40581	intact:EBI-7055862|ensembl:ENSP00000233047|ensembl:ENSP00000261388|ensembl:ENSP00000460687|ensembl:ENSP00000492164|ensembl:ENSP00000492501|ensembl:ENSP00000491056|intact:MINT-8163962|intact:MINT-8201794|uniprotkb:A6NMA9|uniprotkb:O00323|uniprotkb:B4DEC1	intact:EBI-7869|ensemblfungi:YIR037W|uniprotkb:D6VVW8	psi-mi:ldaf1_human(display_long)|uniprotkb:LDAF1(gene name)|psi-mi:LDAF1(display_short)|uniprotkb:Promethin(gene name synonym)|uniprotkb:TMEM159(gene name synonym)|uniprotkb:Transmembrane protein 159(gene name synonym)	psi-mi:gpx3_yeast(display_long)|uniprotkb:HYR1(gene name)|psi-mi:HYR1(display_short)|uniprotkb:ORP1(gene name synonym)|uniprotkb:Hydrogen peroxide resistance protein 1(gene name synonym)|uniprotkb:Oxidant receptor peroxidase 1(gene name synonym)|uniprotkb:Phospholipid hydroperoxide glutathione peroxidase 3(gene name synonym)|uniprotkb:GPX3(gene name synonym)|uniprotkb:YIR037W(locus name)|uniprotkb:Glutathione peroxidase homolog 3(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553264|imex:IM-24995-3887	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001288698.1|refseq:NP_001288700.1|refseq:NP_001288702.1|refseq:NP_001288703.1|refseq:NP_001288704.1|ensembl:ENSG00000011638(gene)|ensembl:ENSG00000283997(gene)|ensembl:ENST00000233047(transcript)|ensembl:ENST00000261388(transcript)|ensembl:ENST00000572599(transcript)|ensembl:ENST00000638934(transcript)|ensembl:ENST00000640188(transcript)|ensembl:ENST00000640514(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0016021"(integral component of membrane)|go:"GO:0140042"(lipid droplet formation)|interpro:IPR029709|mint:Q96B96|refseq:NP_065155.3|refseq:XP_005255496.1|refseq:XP_006721129.1	refseq:NP_012303.1|sgd:S000001476|ensemblfungi:YIR037W(gene)|ensemblfungi:YIR037W_mRNA(transcript)|go:"GO:0004601"(peroxidase activity)|go:"GO:0004602"(glutathione peroxidase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005829"(cytosol)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0047066"(phospholipid-hydroperoxide glutathione peroxidase activity)|go:"GO:0051920"(peroxiredoxin activity)|interpro:IPR000889(Glutathione peroxidase)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR029760|interpro:IPR036249|rcsb pdb:3CMI|reactome:R-SCE-2142712|reactome:R-SCE-9018676|reactome:R-SCE-9018896|reactome:R-SCE-9020265|reactome:R-SCE-9023661|interpro:IPR029759|mint:P40581|dip:DIP-1275N	-	comment:mint	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:qDMjn8OVxY8eRUFJTc8hxD3Tk0c9606	rogid:Pi8aaZEVc33CTMPyaM0mpscvLU4559292	intact-crc:0B90F4DE8E95B81B|rigid:mgnY5oY9Y6iSPiFRmMFG4UvDHng	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96AT9	uniprotkb:P32502	intact:EBI-372480|uniprotkb:O43767|uniprotkb:Q8N215|uniprotkb:Q96N34|uniprotkb:Q9BSB5|uniprotkb:B4E016|ensembl:ENSP00000352401|uniprotkb:A8K4S0|uniprotkb:C9JPQ7|uniprotkb:Q53TV9	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:rpe_human(display_long)|uniprotkb:Ribulose-5-phosphate-3-epimerase(gene name synonym)|uniprotkb:RPE(gene name)|psi-mi:RPE(display_short)|uniprotkb:HUSSY-17(orf name)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553260|imex:IM-24995-3886	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000197713(gene)|ensembl:ENST00000359429(transcript)|go:"GO:0004750"(D-ribulose-phosphate 3-epimerase activity)|go:"GO:0005829"(cytosol)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006098"(pentose-phosphate shunt)|go:"GO:0009052"(pentose-phosphate shunt, non-oxidative branch)|go:"GO:0019323"(pentose catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044262"(cellular carbohydrate metabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000056(Ribulose-phosphate 3-epimerase)|interpro:IPR011060(Ribulose-phosphate binding barrel)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR026019|rcsb pdb:3OVP|rcsb pdb:3OVQ|rcsb pdb:3OVR|rcsb pdb:3QC3|reactome:R-HSA-71336|refseq:NP_008847.1|refseq:NP_954699.1|refseq:NP_001305855.1|refseq:NP_001305856.1|refseq:NP_001305857.1|refseq:NP_001305858.1|refseq:NP_001305859.1|refseq:NP_001305860.1|refseq:NP_001265211.1|refseq:NP_001265212.1|refseq:NP_001265214.1|refseq:NP_001265215.1|refseq:NP_001265217.1|refseq:NP_001265218.1|refseq:XP_006712740.1	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731	-	-	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:lFQZZpLsSKKpUv9o+wSEvPlqG989606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:DDD31AF085F4B11A|rigid:pD+x8gZiGJrTozR0guYJRc/6Mgs	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q03768	uniprotkb:Q96AA8	intact:EBI-7618|uniprotkb:D6VSD4|ensemblfungi:YDR152W	intact:EBI-752007|uniprotkb:O60302|uniprotkb:B4DSG0|uniprotkb:A4ZZA7|uniprotkb:Q548S1|uniprotkb:A8K5G5|uniprotkb:G5E9Y0|ensembl:ENSP00000265272	psi-mi:gir2_yeast(display_long)|uniprotkb:GIR2(gene name)|psi-mi:GIR2(display_short)|uniprotkb:YDR152W(locus name)|uniprotkb:YD8358.08(orf name)|uniprotkb:DFRP2(gene name synonym)|uniprotkb:DRG family-regulatory protein 2(gene name synonym)|uniprotkb:Genetically interacts with ribosomal genes protein 2(gene name synonym)	psi-mi:jkip2_human(display_long)|uniprotkb:JAMIP2(gene name synonym)|uniprotkb:NECC1(gene name synonym)|uniprotkb:Neuroendocrine long coiled-coil protein 1(gene name synonym)|uniprotkb:CTCL tumor antigen HD-CL-04(gene name synonym)|uniprotkb:JAKMIP2(gene name)|psi-mi:JAKMIP2(display_short)|uniprotkb:KIAA0555(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553248|imex:IM-24995-3883	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002559|refseq:NP_010436.3|mint:Q03768|dip:DIP-1751N|ensemblfungi:YDR152W(gene)|ensemblfungi:YDR152W_mRNA(transcript)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005844"(polysome)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:1903833"(positive regulation of cellular response to amino acid starvation)|interpro:IPR006575(RWD)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR040213	refseq:NP_055605.2|refseq:NP_001257870.1|refseq:NP_001257863.1|refseq:NP_001269211.1|refseq:XP_016865586.1|ensembl:ENSG00000176049(gene)|ensembl:ENST00000265272(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0008017"(microtubule binding)|go:"GO:0019900"(kinase binding)|interpro:IPR024836|interpro:IPR031994	-	crc64:CE09A067388638ED	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:2gb8Bf2IGl8RoOmNcIvEMlmgeTE559292	rogid:WnaHkeDBQXut9F9AzzaCrDYpmAE9606	intact-crc:1EFE136A67E2C898|rigid:f3XZjsvsBmJONZLjVfhud9qGzeo	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96AA8	uniprotkb:P38340	intact:EBI-752007|uniprotkb:O60302|uniprotkb:B4DSG0|uniprotkb:A4ZZA7|uniprotkb:Q548S1|uniprotkb:A8K5G5|uniprotkb:G5E9Y0|ensembl:ENSP00000265272	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:jkip2_human(display_long)|uniprotkb:JAMIP2(gene name synonym)|uniprotkb:NECC1(gene name synonym)|uniprotkb:Neuroendocrine long coiled-coil protein 1(gene name synonym)|uniprotkb:CTCL tumor antigen HD-CL-04(gene name synonym)|uniprotkb:JAKMIP2(gene name)|psi-mi:JAKMIP2(display_short)|uniprotkb:KIAA0555(gene name synonym)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553252|imex:IM-24995-3884	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055605.2|refseq:NP_001257870.1|refseq:NP_001257863.1|refseq:NP_001269211.1|refseq:XP_016865586.1|ensembl:ENSG00000176049(gene)|ensembl:ENST00000265272(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0008017"(microtubule binding)|go:"GO:0019900"(kinase binding)|interpro:IPR024836|interpro:IPR031994	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F	-	-	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:WnaHkeDBQXut9F9AzzaCrDYpmAE9606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:580A4ECFA53AC3E3|rigid:npYgIZdHQ/NERxzGsNzFH1B4wyU	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96AA8	uniprotkb:P26448	intact:EBI-752007|uniprotkb:O60302|uniprotkb:B4DSG0|uniprotkb:A4ZZA7|uniprotkb:Q548S1|uniprotkb:A8K5G5|uniprotkb:G5E9Y0|ensembl:ENSP00000265272	intact:EBI-3824|uniprotkb:D6VZN0|ensemblfungi:YMR055C	psi-mi:jkip2_human(display_long)|uniprotkb:JAMIP2(gene name synonym)|uniprotkb:NECC1(gene name synonym)|uniprotkb:Neuroendocrine long coiled-coil protein 1(gene name synonym)|uniprotkb:CTCL tumor antigen HD-CL-04(gene name synonym)|uniprotkb:JAKMIP2(gene name)|psi-mi:JAKMIP2(display_short)|uniprotkb:KIAA0555(gene name synonym)	psi-mi:bub2_yeast(display_long)|uniprotkb:BUB2(gene name)|psi-mi:BUB2(display_short)|uniprotkb:YMR055C(locus name)|uniprotkb:YM9796.08C(orf name)|uniprotkb:Cell cycle arrest protein BUB2(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553256|imex:IM-24995-3885	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055605.2|refseq:NP_001257870.1|refseq:NP_001257863.1|refseq:NP_001269211.1|refseq:XP_016865586.1|ensembl:ENSG00000176049(gene)|ensembl:ENST00000265272(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0008017"(microtubule binding)|go:"GO:0019900"(kinase binding)|interpro:IPR024836|interpro:IPR031994	refseq:NP_013771.1|sgd:S000004659|dip:DIP-1215N|mint:P26448|ensemblfungi:YMR055C(gene)|ensemblfungi:YMR055C_mRNA(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0031030"(negative regulation of septation initiation signaling)|go:"GO:0031578"(mitotic spindle orientation checkpoint signaling)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0051301"(cell division)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:1902543"(negative regulation of protein localization to mitotic spindle pole body)|go:"GO:1990334"(Bfa1-Bub2 complex)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR035969	-	-	crc64:A1DDBFB548E81EA3	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:WnaHkeDBQXut9F9AzzaCrDYpmAE9606	rogid:+03m4HOOcKjpSjqpEZ8wCgD2Egc559292	intact-crc:B1AF4E5086E7EB31|rigid:QAgHLUiC270GVGiAuKnK088snIY	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96BA8	uniprotkb:Q04969	intact:EBI-6942903|ensembl:ENSP00000481956|intact:MINT-268046|intact:MINT-8162577|uniprotkb:Q8N2D5|uniprotkb:Q96CP0	intact:EBI-27827|uniprotkb:D6VZB9|ensemblfungi:YML055W	psi-mi:cr3l1_human(display_long)|uniprotkb:CREB3L1(gene name)|psi-mi:CREB3L1(display_short)|uniprotkb:OASIS(gene name synonym)|uniprotkb:PSEC0238(orf name)|uniprotkb:Old astrocyte specifically-induced substance(gene name synonym)	psi-mi:spc2_yeast(display_long)|uniprotkb:YML055W(locus name)|uniprotkb:YM9958.07(orf name)|uniprotkb:SPC2(gene name)|psi-mi:SPC2(display_short)|uniprotkb:SPY1(gene name synonym)|uniprotkb:Microsomal signal peptidase subunit 2(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553280|imex:IM-24995-3891	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157613(gene)|ensembl:ENST00000621158(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0070278"(extracellular matrix constituent secretion)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029805|mint:Q96BA8|reactome:R-HSA-8874211|refseq:NP_443086.1	refseq:NP_013657.1|sgd:S000004519|dip:DIP-4540N|mint:Q04969|ensemblfungi:YML055W(gene)|ensemblfungi:YML055W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005787"(signal peptidase complex)|go:"GO:0006465"(signal peptide processing)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045047"(protein targeting to ER)|go:"GO:0120236"(negative regulation of posttranslational protein targeting to membrane, translocation)|interpro:IPR009582(Microsomal signal peptidase 25 kDa subunit)	-	comment:mint|function:"Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE"	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:sMWUFmBeBBCO+T0Y2CuB/un1lBg9606	rogid:ZXf9rPA3/ryPnDqI4JGp0VMNMe4559292	intact-crc:157D190D80234BB7|rigid:4iUkH+SMctTR3eWg5hEqFhhupzc	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96BA8	intact:EBI-11522518	intact:EBI-6942903|ensembl:ENSP00000481956|intact:MINT-268046|intact:MINT-8162577|uniprotkb:Q8N2D5|uniprotkb:Q96CP0	-	psi-mi:cr3l1_human(display_long)|uniprotkb:CREB3L1(gene name)|psi-mi:CREB3L1(display_short)|uniprotkb:OASIS(gene name synonym)|uniprotkb:PSEC0238(orf name)|uniprotkb:Old astrocyte specifically-induced substance(gene name synonym)	psi-mi:ost2(display_short)|psi-mi:EBI-11522518(display_long)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553276|imex:IM-24995-3890	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157613(gene)|ensembl:ENST00000621158(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0070278"(extracellular matrix constituent secretion)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029805|mint:Q96BA8|reactome:R-HSA-8874211|refseq:NP_443086.1	-	-	comment:mint|function:"Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE"	no-uniprot-update:	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:sMWUFmBeBBCO+T0Y2CuB/un1lBg9606	rogid:3gHEG/j4fiaHHY/qWGorqbRMBsg4932	intact-crc:96A09B36BD59A68E|rigid:XEPVU11Ksmf99eDRO+Gztb1+AeY	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96BA8	uniprotkb:P05375	intact:EBI-6942903|ensembl:ENSP00000481956|intact:MINT-268046|intact:MINT-8162577|uniprotkb:Q8N2D5|uniprotkb:Q96CP0	intact:EBI-13119|uniprotkb:D6VWP3|ensemblfungi:YJR073C	psi-mi:cr3l1_human(display_long)|uniprotkb:CREB3L1(gene name)|psi-mi:CREB3L1(display_short)|uniprotkb:OASIS(gene name synonym)|uniprotkb:PSEC0238(orf name)|uniprotkb:Old astrocyte specifically-induced substance(gene name synonym)	psi-mi:plmt_yeast(display_long)|uniprotkb:OPI3(gene name)|psi-mi:OPI3(display_short)|uniprotkb:PEM2(gene name synonym)|uniprotkb:Overproducer of inositol protein 3(gene name synonym)|uniprotkb:Phospholipid methyltransferase(gene name synonym)|uniprotkb:J1824(orf name)|uniprotkb:YJR073C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553272|imex:IM-24995-3889	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157613(gene)|ensembl:ENST00000621158(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0070278"(extracellular matrix constituent secretion)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029805|mint:Q96BA8|reactome:R-HSA-8874211|refseq:NP_443086.1	refseq:NP_012607.1|sgd:S000003834|reactome:R-SCE-1483191|dip:DIP-2888N|ensemblfungi:YJR073C(gene)|ensemblfungi:YJR073C_mRNA(transcript)|go:"GO:0000773"(phosphatidyl-N-methylethanolamine N-methyltransferase activity)|go:"GO:0004608"(phosphatidylethanolamine N-methyltransferase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006656"(phosphatidylcholine biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032259"(methylation)|go:"GO:0071944"(cell periphery)|go:"GO:0080101"(phosphatidyl-N-dimethylethanolamine N-methyltransferase activity)|interpro:IPR007318(Phospholipid methyltransferase)|interpro:IPR024960	-	comment:mint|function:"Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE"	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:sMWUFmBeBBCO+T0Y2CuB/un1lBg9606	rogid:5jLJ+pCvOmgw3FFJDmZ5HOwI+BI559292	intact-crc:F884AB76FC8FC1F6|rigid:mak0qGTKwIm2BLg50IeXlVkEyiA	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96BA8	uniprotkb:P46956	intact:EBI-6942903|ensembl:ENSP00000481956|intact:MINT-268046|intact:MINT-8162577|uniprotkb:Q8N2D5|uniprotkb:Q96CP0	intact:EBI-13337|uniprotkb:E9P8T7|ensemblfungi:YJL117W|uniprotkb:D6VW67	psi-mi:cr3l1_human(display_long)|uniprotkb:CREB3L1(gene name)|psi-mi:CREB3L1(display_short)|uniprotkb:OASIS(gene name synonym)|uniprotkb:PSEC0238(orf name)|uniprotkb:Old astrocyte specifically-induced substance(gene name synonym)	psi-mi:pho86_yeast(display_long)|uniprotkb:PHO86(gene name)|psi-mi:PHO86(display_short)|uniprotkb:J0744(orf name)|uniprotkb:YJL117W(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553268|imex:IM-24995-3888	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157613(gene)|ensembl:ENST00000621158(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0070278"(extracellular matrix constituent secretion)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029805|mint:Q96BA8|reactome:R-HSA-8874211|refseq:NP_443086.1	refseq:NP_012418.1|sgd:S000003653|interpro:IPR024297|ensemblfungi:YJL117W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006457"(protein folding)|go:"GO:0006817"(phosphate ion transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0010966"(regulation of phosphate transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0051082"(unfolded protein binding)|ensemblfungi:YJL117W(gene)|mint:P46956|dip:DIP-2769N	-	comment:mint|function:"Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE"	crc64:1CB19C9184BF1C48	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:sMWUFmBeBBCO+T0Y2CuB/un1lBg9606	rogid:JITWReptfMoij1Uy6y1e3Oa6dAs559292	intact-crc:ADE08A52891CD132|rigid:zNFUhUB559mW5v40Np8eyOmhspM	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96BA8	uniprotkb:Q12006	intact:EBI-6942903|ensembl:ENSP00000481956|intact:MINT-268046|intact:MINT-8162577|uniprotkb:Q8N2D5|uniprotkb:Q96CP0	intact:EBI-36378|uniprotkb:D6W264|ensemblfungi:YOL003C	psi-mi:cr3l1_human(display_long)|uniprotkb:CREB3L1(gene name)|psi-mi:CREB3L1(display_short)|uniprotkb:OASIS(gene name synonym)|uniprotkb:PSEC0238(orf name)|uniprotkb:Old astrocyte specifically-induced substance(gene name synonym)	psi-mi:pfa4_yeast(display_long)|uniprotkb:PFA4(gene name)|psi-mi:PFA4(display_short)|uniprotkb:UNE378(orf name)|uniprotkb:Protein fatty acyltransferase 4(gene name synonym)|uniprotkb:YOL003C(locus name)|uniprotkb:Protein S-acyltransferase(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553284|imex:IM-24995-3892	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157613(gene)|ensembl:ENST00000621158(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0070278"(extracellular matrix constituent secretion)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029805|mint:Q96BA8|reactome:R-HSA-8874211|refseq:NP_443086.1	refseq:NP_014640.1|sgd:S000005363|dip:DIP-4248N|reactome:R-SCE-203615|ensemblfungi:YOL003C(gene)|ensemblfungi:YOL003C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|interpro:IPR001594(Zinc finger, DHHC-type)|interpro:IPR033682	-	comment:mint|function:"Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE"	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:sMWUFmBeBBCO+T0Y2CuB/un1lBg9606	rogid:yzNswK8Xpbra0kf0p0cRh+CXCqo559292	intact-crc:E0BDC84DA304774C|rigid:j03lKme0dkUdMvCvlrnvcab836E	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96BA8	uniprotkb:Q06144	intact:EBI-6942903|ensembl:ENSP00000481956|intact:MINT-268046|intact:MINT-8162577|uniprotkb:Q8N2D5|uniprotkb:Q96CP0	intact:EBI-34916|uniprotkb:D6VYY8|ensemblfungi:YLR350W	psi-mi:cr3l1_human(display_long)|uniprotkb:CREB3L1(gene name)|psi-mi:CREB3L1(display_short)|uniprotkb:OASIS(gene name synonym)|uniprotkb:PSEC0238(orf name)|uniprotkb:Old astrocyte specifically-induced substance(gene name synonym)	psi-mi:orm2_yeast(display_long)|uniprotkb:ORM2(gene name)|psi-mi:ORM2(display_short)|uniprotkb:YLR350W(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553304|imex:IM-24995-3897	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157613(gene)|ensembl:ENST00000621158(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0070278"(extracellular matrix constituent secretion)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029805|mint:Q96BA8|reactome:R-HSA-8874211|refseq:NP_443086.1	refseq:NP_013454.1|sgd:S000004342|mint:Q06144|dip:DIP-5579N|ensemblfungi:YLR350W(gene)|ensemblfungi:YLR350W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035339"(SPOTS complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0090155"(negative regulation of sphingolipid biosynthetic process)|go:"GO:0090156"(cellular sphingolipid homeostasis)|go:"GO:1900060"(negative regulation of ceramide biosynthetic process)|interpro:IPR007203(ORMDL)|reactome:R-SCE-6798695	-	comment:mint|function:"Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE"	crc64:2F474503CAB7C195	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:sMWUFmBeBBCO+T0Y2CuB/un1lBg9606	rogid:sY9Jt1Ogpw+lL+9cnBqUeXBiBdE559292	intact-crc:B4B9903128DC5151|rigid:6cdPaXf69FAZGGC+M/4eauab+6w	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96BA8	uniprotkb:P42836	intact:EBI-6942903|ensembl:ENSP00000481956|intact:MINT-268046|intact:MINT-8162577|uniprotkb:Q8N2D5|uniprotkb:Q96CP0	intact:EBI-28414|uniprotkb:D6W0M1|ensemblfungi:YNL326C	psi-mi:cr3l1_human(display_long)|uniprotkb:CREB3L1(gene name)|psi-mi:CREB3L1(display_short)|uniprotkb:OASIS(gene name synonym)|uniprotkb:PSEC0238(orf name)|uniprotkb:Old astrocyte specifically-induced substance(gene name synonym)	psi-mi:pfa3_yeast(display_long)|uniprotkb:YNL326C(locus name)|uniprotkb:N0325(orf name)|uniprotkb:PFA3(gene name)|psi-mi:PFA3(display_short)|uniprotkb:Protein fatty acyltransferase 3(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553300|imex:IM-24995-3896	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157613(gene)|ensembl:ENST00000621158(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0070278"(extracellular matrix constituent secretion)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029805|mint:Q96BA8|reactome:R-HSA-8874211|refseq:NP_443086.1	refseq:NP_014073.1|sgd:S000005270|dip:DIP-4833N|ensemblfungi:YNL326C(gene)|ensemblfungi:YNL326C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0042144"(vacuole fusion, non-autophagic)|interpro:IPR001594(Zinc finger, DHHC-type)	-	comment:mint|function:"Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE"	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:sMWUFmBeBBCO+T0Y2CuB/un1lBg9606	rogid:wDUIzJoLnfaV6fo96hca+beyKb4559292	intact-crc:34F65FFEAB6DDB10|rigid:+paqGEhcUkhG4sNChbNbQOAbHo0	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96BA8	uniprotkb:P47088	intact:EBI-6942903|ensembl:ENSP00000481956|intact:MINT-268046|intact:MINT-8162577|uniprotkb:Q8N2D5|uniprotkb:Q96CP0	intact:EBI-26307|uniprotkb:D6VWI9|uniprotkb:E9P8R4|ensemblfungi:YJR013W	psi-mi:cr3l1_human(display_long)|uniprotkb:CREB3L1(gene name)|psi-mi:CREB3L1(display_short)|uniprotkb:OASIS(gene name synonym)|uniprotkb:PSEC0238(orf name)|uniprotkb:Old astrocyte specifically-induced substance(gene name synonym)	psi-mi:gpi14_yeast(display_long)|uniprotkb:GPI mannosyltransferase I(gene name synonym)|uniprotkb:Glycosylphosphatidylinositol-anchor biosynthesis protein 14(gene name synonym)|uniprotkb:YJR013W(locus name)|uniprotkb:J1444(orf name)|uniprotkb:YJR83.11(orf name)|uniprotkb:GPI14(gene name)|psi-mi:GPI14(display_short)|uniprotkb:PMH1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553288|imex:IM-24995-3893	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157613(gene)|ensembl:ENST00000621158(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0070278"(extracellular matrix constituent secretion)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029805|mint:Q96BA8|reactome:R-HSA-8874211|refseq:NP_443086.1	refseq:NP_012547.2|sgd:S000003774|interpro:IPR007704(Mannosyltransferase, DXD)|ensemblfungi:YJR013W(gene)|ensemblfungi:YJR013W_mRNA(transcript)|go:"GO:0004376"(glycolipid mannosyltransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006506"(GPI anchor biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0051751"(alpha-1,4-mannosyltransferase activity)|go:"GO:1990529"(glycosylphosphatidylinositol-mannosyltransferase I complex)	-	comment:mint|function:"Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE"	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:sMWUFmBeBBCO+T0Y2CuB/un1lBg9606	rogid:I8WI1aDIsik8nbDq7V/vf4UY9oQ559292	intact-crc:B38B79C29F40C16B|rigid:t6bn5S4A1t6XXfXKIRvCY7ja3UE	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96BA8	uniprotkb:P38736	intact:EBI-6942903|ensembl:ENSP00000481956|intact:MINT-268046|intact:MINT-8162577|uniprotkb:Q8N2D5|uniprotkb:Q96CP0	intact:EBI-24365|uniprotkb:D3DKT7|ensemblfungi:YHL031C	psi-mi:cr3l1_human(display_long)|uniprotkb:CREB3L1(gene name)|psi-mi:CREB3L1(display_short)|uniprotkb:OASIS(gene name synonym)|uniprotkb:PSEC0238(orf name)|uniprotkb:Old astrocyte specifically-induced substance(gene name synonym)	psi-mi:gosr1_yeast(display_long)|uniprotkb:Golgi SNARE protein 1(gene name synonym)|uniprotkb:GOS1(gene name)|psi-mi:GOS1(display_short)|uniprotkb:Protein transport protein GOS1(gene name synonym)|uniprotkb:YHL031C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553292|imex:IM-24995-3894	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157613(gene)|ensembl:ENST00000621158(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0070278"(extracellular matrix constituent secretion)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029805|mint:Q96BA8|reactome:R-HSA-8874211|refseq:NP_443086.1	refseq:NP_011832.1|sgd:S000001023|reactome:R-SCE-6811438|dip:DIP-2490N|reactome:R-SCE-6807878|ensemblfungi:YHL031C(gene)|ensemblfungi:YHL031C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005797"(Golgi medial cisterna)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0048193"(Golgi vesicle transport)|go:"GO:0048209"(regulation of vesicle targeting, to, from or within Golgi)|interpro:IPR023601|go:"GO:0006906"(vesicle fusion)	-	comment:mint|function:"Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE"	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:sMWUFmBeBBCO+T0Y2CuB/un1lBg9606	rogid:pAzDzV46XXzIOB4p/oc1PlMc54E559292	intact-crc:673230A622877349|rigid:nyLw3FZJsmx2KHNyGUz8o3CuFSk	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96BA8	uniprotkb:P47190	intact:EBI-6942903|ensembl:ENSP00000481956|intact:MINT-268046|intact:MINT-8162577|uniprotkb:Q8N2D5|uniprotkb:Q96CP0	intact:EBI-13579|uniprotkb:D6W319|ensemblfungi:YOR321W	psi-mi:cr3l1_human(display_long)|uniprotkb:CREB3L1(gene name)|psi-mi:CREB3L1(display_short)|uniprotkb:OASIS(gene name synonym)|uniprotkb:PSEC0238(orf name)|uniprotkb:Old astrocyte specifically-induced substance(gene name synonym)	psi-mi:pmt3_yeast(display_long)|uniprotkb:PMT3(gene name)|psi-mi:PMT3(display_short)|uniprotkb:O6148(orf name)|uniprotkb:YOR321W(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553296|imex:IM-24995-3895	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157613(gene)|ensembl:ENST00000621158(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0070278"(extracellular matrix constituent secretion)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029805|mint:Q96BA8|reactome:R-HSA-8874211|refseq:NP_443086.1	refseq:NP_014966.1|sgd:S000005848|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:0097582"(dolichyl-phosphate-mannose-protein mannosyltransferase Pmt1p-Pmt2p dimer complex)|go:"GO:0097583"(dolichyl-phosphate-mannose-protein mannosyltransferase Pmt1p-Pmt3p dimer complex)|go:"GO:0097585"(dolichyl-phosphate-mannose-protein mannosyltransferase Pmt5p-Pmt3p dimer complex)|interpro:IPR003342(Glycosyl transferase, family 39)|interpro:IPR016093(MIR motif)|interpro:IPR027005|interpro:IPR032421|ensemblfungi:YOR321W(gene)|ensemblfungi:YOR321W_mRNA(transcript)|go:"GO:0004169"(dolichyl-phosphate-mannose-protein mannosyltransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006493"(protein O-linked glycosylation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035269"(protein O-linked mannosylation)|interpro:IPR036300|rcsb pdb:6ZQQ|dip:DIP-5158N	-	comment:mint|function:"Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE"	crc64:F076473B41EB6CBA	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:sMWUFmBeBBCO+T0Y2CuB/un1lBg9606	rogid:JsPUkzaK8sNWifvo5m9Ixhly2P8559292	intact-crc:DA2462349EE07591|rigid:xKfN74/ZVuRBhxSOHz5/z8hDN4A	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96BA8	uniprotkb:P23968	intact:EBI-6942903|ensembl:ENSP00000481956|intact:MINT-268046|intact:MINT-8162577|uniprotkb:Q8N2D5|uniprotkb:Q96CP0	intact:EBI-20293|uniprotkb:D3DKX3|ensemblfungi:YHR026W	psi-mi:cr3l1_human(display_long)|uniprotkb:CREB3L1(gene name)|psi-mi:CREB3L1(display_short)|uniprotkb:OASIS(gene name synonym)|uniprotkb:PSEC0238(orf name)|uniprotkb:Old astrocyte specifically-induced substance(gene name synonym)	psi-mi:vato_yeast(display_long)|uniprotkb:VMA16(gene name)|psi-mi:VMA16(display_short)|uniprotkb:PPA1(gene name synonym)|uniprotkb:YHR026W(locus name)|uniprotkb:Vacuolar proton pump c'' subunit(gene name synonym)|uniprotkb:V-ATPase 22 kDa proteolipid subunit(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553320|imex:IM-24995-3901	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157613(gene)|ensembl:ENST00000621158(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0070278"(extracellular matrix constituent secretion)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029805|mint:Q96BA8|reactome:R-HSA-8874211|refseq:NP_443086.1	refseq:NP_011891.1|sgd:S000001068|rcsb pdb:6O7W|rcsb pdb:6O7X|rcsb pdb:6PE4|rcsb pdb:6PE5|reactome:R-SCE-1222556|reactome:R-SCE-77387|reactome:R-SCE-917977|reactome:R-SCE-9639288|ensemblfungi:YHR026W(gene)|ensemblfungi:YHR026W_mRNA(transcript)|go:"GO:0000220"(vacuolar proton-transporting V-type ATPase, V0 domain)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0008553"(P-type proton-exporting transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016471"(vacuolar proton-transporting V-type ATPase complex)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR000245(ATPase, V0 complex, proteolipid subunit C,)|interpro:IPR002379(ATPase, F0/V0 complex, subunit C)|interpro:IPR035921|rcsb pdb:5TJ5|rcsb pdb:5VOX|rcsb pdb:5VOY|rcsb pdb:5VOZ|rcsb pdb:6C6L|rcsb pdb:6M0R|rcsb pdb:6M0S|rcsb pdb:6O7T|rcsb pdb:6O7U|rcsb pdb:6O7V|dip:DIP-4054N|mint:P23968	-	comment:mint|function:"Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE"	crc64:033FF5A516B97F8B	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:sMWUFmBeBBCO+T0Y2CuB/un1lBg9606	rogid:pQMMMGsUAtBoa6IF8yVU2t+odQQ559292	intact-crc:DD49264A41DA1B24|rigid:yZXLin542GrbPE4nOM51K4bgRXA	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96BA8	uniprotkb:P53173	intact:EBI-6942903|ensembl:ENSP00000481956|intact:MINT-268046|intact:MINT-8162577|uniprotkb:Q8N2D5|uniprotkb:Q96CP0	intact:EBI-6633|uniprotkb:D6VU87|ensemblfungi:YGL054C	psi-mi:cr3l1_human(display_long)|uniprotkb:CREB3L1(gene name)|psi-mi:CREB3L1(display_short)|uniprotkb:OASIS(gene name synonym)|uniprotkb:PSEC0238(orf name)|uniprotkb:Old astrocyte specifically-induced substance(gene name synonym)	psi-mi:erv14_yeast(display_long)|uniprotkb:ERV14(gene name)|psi-mi:ERV14(display_short)|uniprotkb:YGL054C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553308|imex:IM-24995-3898	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157613(gene)|ensembl:ENST00000621158(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0070278"(extracellular matrix constituent secretion)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029805|mint:Q96BA8|reactome:R-HSA-8874211|refseq:NP_443086.1	refseq:NP_011461.1|sgd:S000003022|dip:DIP-5457N|ensemblfungi:YGL054C(gene)|ensemblfungi:YGL054C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007120"(axial cellular bud site selection)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0030437"(ascospore formation)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0071944"(cell periphery)|go:"GO:1902684"(negative regulation of receptor localization to synapse)|go:"GO:2000311"(regulation of AMPA receptor activity)|interpro:IPR003377(Cornichon)|interpro:IPR033466	-	comment:mint|function:"Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE"	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:sMWUFmBeBBCO+T0Y2CuB/un1lBg9606	rogid:KxwdOCXkpx+NMjtv4y+kU2ID99M559292	intact-crc:A1007FB666C1A7E8|rigid:U6rII9M7DePFPuypuFYYswtZoiM	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96BA8	uniprotkb:Q03362	intact:EBI-6942903|ensembl:ENSP00000481956|intact:MINT-268046|intact:MINT-8162577|uniprotkb:Q8N2D5|uniprotkb:Q96CP0	intact:EBI-2057915|uniprotkb:D6VT99|ensemblfungi:YDR476C	psi-mi:cr3l1_human(display_long)|uniprotkb:CREB3L1(gene name)|psi-mi:CREB3L1(display_short)|uniprotkb:OASIS(gene name synonym)|uniprotkb:PSEC0238(orf name)|uniprotkb:Old astrocyte specifically-induced substance(gene name synonym)	psi-mi:yd476_yeast(display_long)|uniprotkb:YDR476C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553312|imex:IM-24995-3899	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157613(gene)|ensembl:ENST00000621158(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0070278"(extracellular matrix constituent secretion)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029805|mint:Q96BA8|reactome:R-HSA-8874211|refseq:NP_443086.1	sgd:S000002884|refseq:NP_010764.1|mint:Q03362|ensemblfungi:YDR476C(gene)|ensemblfungi:YDR476C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)	-	comment:mint|function:"Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE"	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:sMWUFmBeBBCO+T0Y2CuB/un1lBg9606	rogid:YEqaI+xtDR2srSbbY5vQtWY+h6s559292	intact-crc:D4DA3188B996A6B1|rigid:7R5TCt7NUJ/xrrYIJFayBGRGKLQ	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96BA8	uniprotkb:P53906	intact:EBI-6942903|ensembl:ENSP00000481956|intact:MINT-268046|intact:MINT-8162577|uniprotkb:Q8N2D5|uniprotkb:Q96CP0	intact:EBI-28943|ensemblfungi:YNL146W|uniprotkb:D6W137	psi-mi:cr3l1_human(display_long)|uniprotkb:CREB3L1(gene name)|psi-mi:CREB3L1(display_short)|uniprotkb:OASIS(gene name synonym)|uniprotkb:PSEC0238(orf name)|uniprotkb:Old astrocyte specifically-induced substance(gene name synonym)	psi-mi:yno6_yeast(display_long)|uniprotkb:N1203(orf name)|uniprotkb:N1785(orf name)|uniprotkb:YNL146W(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553316|imex:IM-24995-3900	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157613(gene)|ensembl:ENST00000621158(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0070278"(extracellular matrix constituent secretion)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029805|mint:Q96BA8|reactome:R-HSA-8874211|refseq:NP_443086.1	sgd:S000005090|ensemblfungi:YNL146W(gene)|refseq:NP_014253.3|dip:DIP-8009N|ensemblfungi:YNL146W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)	-	comment:mint|function:"Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE"	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:sMWUFmBeBBCO+T0Y2CuB/un1lBg9606	rogid:SvwjVFPBttBj4iLtjQSzRM4+w+E559292	intact-crc:2D9F8E25026CE4DF|rigid:/A0HvqM6hwAcrJl7MjWObv4NNjc	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96BA8	uniprotkb:P40152	intact:EBI-6942903|ensembl:ENSP00000481956|intact:MINT-268046|intact:MINT-8162577|uniprotkb:Q8N2D5|uniprotkb:Q96CP0	intact:EBI-29148|uniprotkb:D6W0X3|ensemblfungi:YNL217W	psi-mi:cr3l1_human(display_long)|uniprotkb:CREB3L1(gene name)|psi-mi:CREB3L1(display_short)|uniprotkb:OASIS(gene name synonym)|uniprotkb:PSEC0238(orf name)|uniprotkb:Old astrocyte specifically-induced substance(gene name synonym)	psi-mi:ynv7_yeast(display_long)|uniprotkb:N1306(orf name)|uniprotkb:YNL217W(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553340|imex:IM-24995-3906	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157613(gene)|ensembl:ENST00000621158(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0070278"(extracellular matrix constituent secretion)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029805|mint:Q96BA8|reactome:R-HSA-8874211|refseq:NP_443086.1	refseq:NP_014182.1|sgd:S000005161|dip:DIP-4934N|ensemblfungi:YNL217W(gene)|ensemblfungi:YNL217W_mRNA(transcript)|go:"GO:0000298"(endopolyphosphatase activity)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005775"(vacuolar lumen)|go:"GO:0006798"(polyphosphate catabolic process)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR029052	-	comment:mint|function:"Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE"	crc64:D69F22A94C4C6684	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:sMWUFmBeBBCO+T0Y2CuB/un1lBg9606	rogid:t4PQ2ND+pPVb7QdkoNSpFPNr+SE559292	intact-crc:BCD2DE77EF4548A7|rigid:hlK3iuu+1zoyfgZlPVMD9BxN8lk	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96BA8	uniprotkb:P47111	intact:EBI-6942903|ensembl:ENSP00000481956|intact:MINT-268046|intact:MINT-8162577|uniprotkb:Q8N2D5|uniprotkb:Q96CP0	intact:EBI-25497|uniprotkb:D6VWL5|ensemblfungi:YJR044C	psi-mi:cr3l1_human(display_long)|uniprotkb:CREB3L1(gene name)|psi-mi:CREB3L1(display_short)|uniprotkb:OASIS(gene name synonym)|uniprotkb:PSEC0238(orf name)|uniprotkb:Old astrocyte specifically-induced substance(gene name synonym)	psi-mi:vps55_yeast(display_long)|uniprotkb:J1637(orf name)|uniprotkb:YJR044C(locus name)|uniprotkb:VPS55(gene name)|psi-mi:VPS55(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553336|imex:IM-24995-3905	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157613(gene)|ensembl:ENST00000621158(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0070278"(extracellular matrix constituent secretion)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029805|mint:Q96BA8|reactome:R-HSA-8874211|refseq:NP_443086.1	sgd:S000003805|refseq:NP_012578.3|dip:DIP-7667N|mint:P47111|ensemblfungi:YJR044C(gene)|ensemblfungi:YJR044C_mRNA(transcript)|go:"GO:0005768"(endosome)|go:"GO:0005770"(late endosome)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0034424"(Vps55/Vps68 complex)|go:"GO:2000009"(negative regulation of protein localization to cell surface)|interpro:IPR007262(Vacuolar protein sorting 55)	-	comment:mint|function:"Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE"	crc64:1F207E62F093FC6D	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:sMWUFmBeBBCO+T0Y2CuB/un1lBg9606	rogid:J23lc6VW+GZsH/Tu+ukXF5QauPg559292	intact-crc:1731B95916EFB4F7|rigid:pDAsg3dJ2BzWP56eURgXagnzwS8	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96BA8	uniprotkb:P40857	intact:EBI-6942903|ensembl:ENSP00000481956|intact:MINT-268046|intact:MINT-8162577|uniprotkb:Q8N2D5|uniprotkb:Q96CP0	intact:EBI-26003|uniprotkb:D6VW87|ensemblfungi:YJL097W	psi-mi:cr3l1_human(display_long)|uniprotkb:CREB3L1(gene name)|psi-mi:CREB3L1(display_short)|uniprotkb:OASIS(gene name synonym)|uniprotkb:PSEC0238(orf name)|uniprotkb:Old astrocyte specifically-induced substance(gene name synonym)	psi-mi:hacd_yeast(display_long)|uniprotkb:YJL097W(locus name)|uniprotkb:J0902(orf name)|uniprotkb:PTPLA homolog involved in sphingolipid biosynthesis protein 1(gene name synonym)|uniprotkb:PHS1(gene name)|psi-mi:PHS1(display_short)|uniprotkb:3-hydroxyacyl-CoA dehydratase PHS1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553324|imex:IM-24995-3902	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157613(gene)|ensembl:ENST00000621158(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0070278"(extracellular matrix constituent secretion)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029805|mint:Q96BA8|reactome:R-HSA-8874211|refseq:NP_443086.1	refseq:NP_012438.1|sgd:S000003633|reactome:R-SCE-75876|dip:DIP-2104N|ensemblfungi:YJL097W(gene)|ensemblfungi:YJL097W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0004300"(enoyl-CoA hydratase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0042175"(nuclear outer membrane-endoplasmic reticulum membrane network)|go:"GO:0042761"(very long-chain fatty acid biosynthetic process)|go:"GO:0102158"(very-long-chain 3-hydroxyacyl-CoA dehydratase activity)|go:"GO:0102343"(3-hydroxy-arachidoyl-CoA dehydratase activity)|go:"GO:0102344"(3-hydroxy-behenoyl-CoA dehydratase activity)|go:"GO:0102345"(3-hydroxy-lignoceroyl-CoA dehydratase activity)|interpro:IPR007482(Protein-tyrosine phosphatase-like, PTPLA)|go:"GO:0007034"(vacuolar transport)|go:"GO:0018812"(3-hydroxyacyl-CoA dehydratase activity)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030497"(fatty acid elongation)	-	comment:mint|function:"Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE"	crc64:5C87BC9563FB83AA	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:sMWUFmBeBBCO+T0Y2CuB/un1lBg9606	rogid:4C/5U50EeqZ6OR+MR8zFHLo36s8559292	intact-crc:E423E26C2CF0554D|rigid:hgunBsGSYaLR369OyA9xNP3usLI	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96BA8	uniprotkb:P40107	intact:EBI-6942903|ensembl:ENSP00000481956|intact:MINT-268046|intact:MINT-8162577|uniprotkb:Q8N2D5|uniprotkb:Q96CP0	intact:EBI-7764|uniprotkb:D6VVB0|ensemblfungi:YGL225W	psi-mi:cr3l1_human(display_long)|uniprotkb:CREB3L1(gene name)|psi-mi:CREB3L1(display_short)|uniprotkb:OASIS(gene name synonym)|uniprotkb:PSEC0238(orf name)|uniprotkb:Old astrocyte specifically-induced substance(gene name synonym)	psi-mi:gmt1_yeast(display_long)|uniprotkb:VRG4(gene name)|psi-mi:VRG4(display_short)|uniprotkb:MCD3(gene name synonym)|uniprotkb:VAN2(gene name synonym)|uniprotkb:GOG5(gene name synonym)|uniprotkb:LDB3(gene name synonym)|uniprotkb:Vanadate resistance glycosylation protein 4(gene name synonym)|uniprotkb:Low dye-binding protein 3(gene name synonym)|uniprotkb:Morphogenesis checkpoint-dependent protein 3(gene name synonym)|uniprotkb:VIG4(gene name synonym)|uniprotkb:YGL225W(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553328|imex:IM-24995-3903	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157613(gene)|ensembl:ENST00000621158(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0070278"(extracellular matrix constituent secretion)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029805|mint:Q96BA8|reactome:R-HSA-8874211|refseq:NP_443086.1	refseq:NP_011290.1|sgd:S000003193|dip:DIP-5108N|ensemblfungi:YGL225W(gene)|ensemblfungi:YGL225W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005458"(GDP-mannose transmembrane transporter activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0008643"(carbohydrate transport)|go:"GO:0015297"(antiporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:1990570"(GDP-mannose transmembrane transport)|interpro:IPR038736|rcsb pdb:5OGE|rcsb pdb:5OGK|rcsb pdb:6QSK	-	comment:mint|function:"Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE"	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:sMWUFmBeBBCO+T0Y2CuB/un1lBg9606	rogid:ZYzY/DU+8rq6BJZz/a4LlZa8I4w559292	intact-crc:E3DAE3490EE87043|rigid:ZzXUPAYRI5Hrp+MRYH8Rif5ZS9A	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96BA8	uniprotkb:P38842	intact:EBI-6942903|ensembl:ENSP00000481956|intact:MINT-268046|intact:MINT-8162577|uniprotkb:Q8N2D5|uniprotkb:Q96CP0	intact:EBI-24752|uniprotkb:D3DL89|uniprotkb:Q6B2K3|ensemblfungi:YHR140W	psi-mi:cr3l1_human(display_long)|uniprotkb:CREB3L1(gene name)|psi-mi:CREB3L1(display_short)|uniprotkb:OASIS(gene name synonym)|uniprotkb:PSEC0238(orf name)|uniprotkb:Old astrocyte specifically-induced substance(gene name synonym)	psi-mi:yhu0_yeast(display_long)|uniprotkb:YHR140W(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553332|imex:IM-24995-3904	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157613(gene)|ensembl:ENST00000621158(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0070278"(extracellular matrix constituent secretion)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029805|mint:Q96BA8|reactome:R-HSA-8874211|refseq:NP_443086.1	refseq:NP_012009.1|sgd:S000001182|dip:DIP-1786N|ensemblfungi:YHR140W(gene)|ensemblfungi:YHR140W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR006838(FAR-17a/AIG1-like protein)	-	comment:mint|function:"Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE"	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:sMWUFmBeBBCO+T0Y2CuB/un1lBg9606	rogid:3CroWy45MlZdD8WyMGvawdwQhrs559292	intact-crc:EB9D1E15942BE613|rigid:0DA9kqjAyPL7wELZ/7YsnW6pIKk	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96BA8	uniprotkb:Q8TGQ7	intact:EBI-6942903|ensembl:ENSP00000481956|intact:MINT-268046|intact:MINT-8162577|uniprotkb:Q8N2D5|uniprotkb:Q96CP0	intact:EBI-2343396|uniprotkb:D6W4G0|ensemblfungi:YPR159C-A	psi-mi:cr3l1_human(display_long)|uniprotkb:CREB3L1(gene name)|psi-mi:CREB3L1(display_short)|uniprotkb:OASIS(gene name synonym)|uniprotkb:PSEC0238(orf name)|uniprotkb:Old astrocyte specifically-induced substance(gene name synonym)	psi-mi:yp159_yeast(display_long)|uniprotkb:YPR159C-A(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553360|imex:IM-24995-3911	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157613(gene)|ensembl:ENST00000621158(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0070278"(extracellular matrix constituent secretion)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029805|mint:Q96BA8|reactome:R-HSA-8874211|refseq:NP_443086.1	sgd:S000028725|refseq:NP_878184.1|ensemblfungi:YPR159C-A(gene)|ensemblfungi:YPR159C-A_mRNA(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0016021"(integral component of membrane)	-	comment:mint|function:"Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE"	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:sMWUFmBeBBCO+T0Y2CuB/un1lBg9606	rogid:QGsci3FKQweBQvaMDdLKyHdq8tM559292	intact-crc:BCE0FCBFDC4C9CAF|rigid:DeHYvscpGsKzoayjNN8/HmV97AI	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96BA8	uniprotkb:Q12382	intact:EBI-6942903|ensembl:ENSP00000481956|intact:MINT-268046|intact:MINT-8162577|uniprotkb:Q8N2D5|uniprotkb:Q96CP0	intact:EBI-36644|uniprotkb:D6W310|ensemblfungi:YOR311C	psi-mi:cr3l1_human(display_long)|uniprotkb:CREB3L1(gene name)|psi-mi:CREB3L1(display_short)|uniprotkb:OASIS(gene name synonym)|uniprotkb:PSEC0238(orf name)|uniprotkb:Old astrocyte specifically-induced substance(gene name synonym)	psi-mi:dgk1_yeast(display_long)|uniprotkb:High-copy suppressor of SLY1 defect protein 1(gene name synonym)|uniprotkb:DGK1(gene name)|psi-mi:DGK1(display_short)|uniprotkb:HSD1(gene name synonym)|uniprotkb:O6111(orf name)|uniprotkb:YOR311C(locus name)|uniprotkb:Diglyceride kinase 1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553356|imex:IM-24995-3910	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157613(gene)|ensembl:ENST00000621158(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0070278"(extracellular matrix constituent secretion)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029805|mint:Q96BA8|reactome:R-HSA-8874211|refseq:NP_443086.1	sgd:S000005838|refseq:NP_014956.3|dip:DIP-5021N|ensemblfungi:YOR311C(gene)|ensemblfungi:YOR311C_mRNA(transcript)|go:"GO:0004143"(diacylglycerol kinase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006654"(phosphatidic acid biosynthetic process)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:2001210"(regulation of isopentenyl diphosphate biosynthetic process, mevalonate pathway)|interpro:IPR037997	-	comment:mint|function:"Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE"	crc64:F8A0EE6F1018025B	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:sMWUFmBeBBCO+T0Y2CuB/un1lBg9606	rogid:/QKdWOYiwS8WsUTob40AL05Q9Hw559292	intact-crc:92AFD62C43193789|rigid:E1chp7hW5Yli2a5YmWKc7tCZS/4	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96BA8	uniprotkb:Q12078	intact:EBI-6942903|ensembl:ENSP00000481956|intact:MINT-268046|intact:MINT-8162577|uniprotkb:Q8N2D5|uniprotkb:Q96CP0	intact:EBI-37834|uniprotkb:D6VY36|ensemblfungi:YLR034C	psi-mi:cr3l1_human(display_long)|uniprotkb:CREB3L1(gene name)|psi-mi:CREB3L1(display_short)|uniprotkb:OASIS(gene name synonym)|uniprotkb:PSEC0238(orf name)|uniprotkb:Old astrocyte specifically-induced substance(gene name synonym)	psi-mi:smf3_yeast(display_long)|uniprotkb:SMF3(gene name)|psi-mi:SMF3(display_short)|uniprotkb:YLR034C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553344|imex:IM-24995-3907	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157613(gene)|ensembl:ENST00000621158(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0070278"(extracellular matrix constituent secretion)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029805|mint:Q96BA8|reactome:R-HSA-8874211|refseq:NP_443086.1	refseq:NP_013134.1|sgd:S000004024|dip:DIP-4163N|mint:Q12078|ensemblfungi:YLR034C(gene)|ensemblfungi:YLR034C_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005384"(manganese ion transmembrane transporter activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006826"(iron ion transport)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0015086"(cadmium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022890"(inorganic cation transmembrane transporter activity)|go:"GO:0030026"(cellular manganese ion homeostasis)|go:"GO:0046872"(metal ion binding)|interpro:IPR001046(Natural resistance-associated macrophage protein)	-	comment:mint|function:"Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE"	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:sMWUFmBeBBCO+T0Y2CuB/un1lBg9606	rogid:H499EDh2oumEUzbjjW4GvAiVFBo559292	intact-crc:6CD0F1EC24E201C2|rigid:YWJmXxkxAkKRFYGR/c+7lgsFwuo	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96BA8	uniprotkb:P40501	intact:EBI-6942903|ensembl:ENSP00000481956|intact:MINT-268046|intact:MINT-8162577|uniprotkb:Q8N2D5|uniprotkb:Q96CP0	intact:EBI-11531370|uniprotkb:D6VVJ9|ensemblfungi:YIL088C	psi-mi:cr3l1_human(display_long)|uniprotkb:CREB3L1(gene name)|psi-mi:CREB3L1(display_short)|uniprotkb:OASIS(gene name synonym)|uniprotkb:PSEC0238(orf name)|uniprotkb:Old astrocyte specifically-induced substance(gene name synonym)	psi-mi:avt7_yeast(display_long)|uniprotkb:AVT7(gene name)|psi-mi:AVT7(display_short)|uniprotkb:YIL088C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553348|imex:IM-24995-3908	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157613(gene)|ensembl:ENST00000621158(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0070278"(extracellular matrix constituent secretion)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029805|mint:Q96BA8|reactome:R-HSA-8874211|refseq:NP_443086.1	refseq:NP_012178.1|sgd:S000001350|ensemblfungi:YIL088C(gene)|ensemblfungi:YIL088C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0003333"(amino acid transmembrane transport)|go:"GO:0005290"(L-histidine transmembrane transporter activity)|go:"GO:0005302"(L-tyrosine transmembrane transporter activity)|go:"GO:0005313"(L-glutamate transmembrane transporter activity)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006865"(amino acid transport)|go:"GO:0015171"(amino acid transmembrane transporter activity)|go:"GO:0015189"(L-lysine transmembrane transporter activity)|go:"GO:0015194"(L-serine transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0043937"(regulation of sporulation)|go:"GO:0061459"(L-arginine transmembrane transporter activity)|interpro:IPR013057(Amino acid transporter, transmembrane)|dip:DIP-7299N	-	comment:mint|function:"Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE"	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/03/16	rogid:sMWUFmBeBBCO+T0Y2CuB/un1lBg9606	rogid:h/wTkn7UHQvjASI16kH6WV6wtC8559292	intact-crc:E8D50096466A7137|rigid:w+mz918KyG6WmrOmroEz0EEF4YQ	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96BA8	uniprotkb:Q03697	intact:EBI-6942903|ensembl:ENSP00000481956|intact:MINT-268046|intact:MINT-8162577|uniprotkb:Q8N2D5|uniprotkb:Q96CP0	intact:EBI-27776|uniprotkb:D6VZD7|ensemblfungi:YML038C	psi-mi:cr3l1_human(display_long)|uniprotkb:CREB3L1(gene name)|psi-mi:CREB3L1(display_short)|uniprotkb:OASIS(gene name synonym)|uniprotkb:PSEC0238(orf name)|uniprotkb:Old astrocyte specifically-induced substance(gene name synonym)	psi-mi:ymd8_yeast(display_long)|uniprotkb:YML038C(locus name)|uniprotkb:YMD8(gene name)|psi-mi:YMD8(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553352|imex:IM-24995-3909	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157613(gene)|ensembl:ENST00000621158(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0070278"(extracellular matrix constituent secretion)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029805|mint:Q96BA8|reactome:R-HSA-8874211|refseq:NP_443086.1	refseq:NP_013674.1|sgd:S000004502|dip:DIP-1312N|mint:Q03697|ensemblfungi:YML038C(gene)|ensemblfungi:YML038C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005338"(nucleotide-sugar transmembrane transporter activity)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0008643"(carbohydrate transport)|go:"GO:0015297"(antiporter activity)|go:"GO:0015780"(nucleotide-sugar transmembrane transport)|go:"GO:0015786"(UDP-glucose transmembrane transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030663"(COPI-coated vesicle membrane)|interpro:IPR004853(Protein of unknown function DUF250)	-	comment:mint|function:"Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE"	crc64:37A03543D3AB695E	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:sMWUFmBeBBCO+T0Y2CuB/un1lBg9606	rogid:i2Fqb84s31vBiayw4lJW8o3S3WU559292	intact-crc:5A4C415DC9DAB6AE|rigid:QWAjWChgf4EUv0/21VdKrY0yHr4	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96BA8	uniprotkb:P40471	intact:EBI-6942903|ensembl:ENSP00000481956|intact:MINT-268046|intact:MINT-8162577|uniprotkb:Q8N2D5|uniprotkb:Q96CP0	intact:EBI-25213|uniprotkb:D6VVG3|ensemblfungi:YIL124W	psi-mi:cr3l1_human(display_long)|uniprotkb:CREB3L1(gene name)|psi-mi:CREB3L1(display_short)|uniprotkb:OASIS(gene name synonym)|uniprotkb:PSEC0238(orf name)|uniprotkb:Old astrocyte specifically-induced substance(gene name synonym)	psi-mi:ayr1_yeast(display_long)|uniprotkb:AYR1(gene name)|psi-mi:AYR1(display_short)|uniprotkb:Acylglycerone-phosphate reductase(gene name synonym)|uniprotkb:1-acyl DHAP reductase(gene name synonym)|uniprotkb:Acyl/alkyl DHAP reductase(gene name synonym)|uniprotkb:GBG1(gene name synonym)|uniprotkb:Triacylglycerol lipase AYR1(gene name synonym)|uniprotkb:YIL124W(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553376|imex:IM-24995-3915	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157613(gene)|ensembl:ENST00000621158(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0070278"(extracellular matrix constituent secretion)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029805|mint:Q96BA8|reactome:R-HSA-8874211|refseq:NP_443086.1	sgd:S000001386|refseq:NP_012142.3|mint:P40471|dip:DIP-4614N|ensemblfungi:YIL124W(gene)|ensemblfungi:YIL124W_mRNA(transcript)|go:"GO:0000140"(acylglycerone-phosphate reductase activity)|go:"GO:0004806"(triglyceride lipase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0006654"(phosphatidic acid biosynthetic process)|go:"GO:0019433"(triglyceride catabolic process)|go:"GO:0102566"(1-acyl dihydroxyacetone phosphate reductase activity)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR020904|interpro:IPR036291	-	comment:mint|function:"Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE"	crc64:B614C0E0B1FB0CE0	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:sMWUFmBeBBCO+T0Y2CuB/un1lBg9606	rogid:WE4RmSXARj683MNUEsYGLis36Xo559292	intact-crc:65D12DD824A3B296|rigid:PIdRZmUwxOaR2abQ9jw56/9k5Oo	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96BA8	uniprotkb:P38374	intact:EBI-6942903|ensembl:ENSP00000481956|intact:MINT-268046|intact:MINT-8162577|uniprotkb:Q8N2D5|uniprotkb:Q96CP0	intact:EBI-29585|uniprotkb:D6VQF8|ensemblfungi:YBR162W-A	psi-mi:cr3l1_human(display_long)|uniprotkb:CREB3L1(gene name)|psi-mi:CREB3L1(display_short)|uniprotkb:OASIS(gene name synonym)|uniprotkb:PSEC0238(orf name)|uniprotkb:Old astrocyte specifically-induced substance(gene name synonym)	psi-mi:ysy6_yeast(display_long)|uniprotkb:YSY6(gene name)|psi-mi:YSY6(display_short)|uniprotkb:YBR162BW(orf name)|uniprotkb:YBR162W-A(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553364|imex:IM-24995-3912	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157613(gene)|ensembl:ENST00000621158(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0070278"(extracellular matrix constituent secretion)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029805|mint:Q96BA8|reactome:R-HSA-8874211|refseq:NP_443086.1	sgd:S000002158|refseq:NP_009721.1|dip:DIP-4936N|reactome:R-SCE-9609523|ensemblfungi:YBR162W-A(gene)|ensemblfungi:YBR162W-A_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006486"(protein glycosylation)|go:"GO:0009306"(protein secretion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|interpro:IPR010580(Ribosome associated membrane RAMP4)	-	comment:mint|function:"Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE"	crc64:326410AB4772B33D	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:sMWUFmBeBBCO+T0Y2CuB/un1lBg9606	rogid:FwDeAMLCEaMmEgCDK1xjQS4MDFg559292	intact-crc:498F28A429EF7569|rigid:wrj9U3bRG1qZzkdHsBORIH0Q+2s	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96BA8	uniprotkb:Q12207	intact:EBI-6942903|ensembl:ENSP00000481956|intact:MINT-268046|intact:MINT-8162577|uniprotkb:Q8N2D5|uniprotkb:Q96CP0	intact:EBI-11922|ensemblfungi:YPR149W|uniprotkb:D6W4E6	psi-mi:cr3l1_human(display_long)|uniprotkb:CREB3L1(gene name)|psi-mi:CREB3L1(display_short)|uniprotkb:OASIS(gene name synonym)|uniprotkb:PSEC0238(orf name)|uniprotkb:Old astrocyte specifically-induced substance(gene name synonym)	psi-mi:nce2_yeast(display_long)|uniprotkb:NCE102(gene name)|psi-mi:NCE102(display_short)|uniprotkb:NCE2(gene name synonym)|uniprotkb:RTG2S2(gene name synonym)|uniprotkb:YPR149W(locus name)|uniprotkb:P9659.2(orf name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553368|imex:IM-24995-3913	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157613(gene)|ensembl:ENST00000621158(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0070278"(extracellular matrix constituent secretion)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029805|mint:Q96BA8|reactome:R-HSA-8874211|refseq:NP_443086.1	ensemblfungi:YPR149W(gene)|ensemblfungi:YPR149W_mRNA(transcript)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0009306"(protein secretion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032126"(eisosome)|go:"GO:0033101"(cellular bud membrane)|go:"GO:0060237"(regulation of fungal-type cell wall organization)|go:"GO:0061091"(regulation of phospholipid translocation)|go:"GO:0070941"(eisosome assembly)|go:"GO:0071944"(cell periphery)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR008253(Marvel)|go:"GO:0070250"(mating projection membrane)|refseq:NP_015475.1|sgd:S000006353|dip:DIP-5397N	-	comment:mint|function:"Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE"	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:sMWUFmBeBBCO+T0Y2CuB/un1lBg9606	rogid:oSD/cLHQuPxlB/s1v7MZUihJ3XM559292	intact-crc:2C533AC162BBF919|rigid:HJ1uGOLC78ud7cdARENohYzFxfM	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96BA8	uniprotkb:P40533	intact:EBI-6942903|ensembl:ENSP00000481956|intact:MINT-268046|intact:MINT-8162577|uniprotkb:Q8N2D5|uniprotkb:Q96CP0	intact:EBI-24998|uniprotkb:D6VVP3|ensemblfungi:YIL039W	psi-mi:cr3l1_human(display_long)|uniprotkb:CREB3L1(gene name)|psi-mi:CREB3L1(display_short)|uniprotkb:OASIS(gene name synonym)|uniprotkb:PSEC0238(orf name)|uniprotkb:Old astrocyte specifically-induced substance(gene name synonym)	psi-mi:ted1_yeast(display_long)|uniprotkb:TED1(gene name)|psi-mi:TED1(display_short)|uniprotkb:Trafficking of EMP24/ERV25-dependent cargo disrupted protein 1(gene name synonym)|uniprotkb:YIL039W(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553372|imex:IM-24995-3914	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157613(gene)|ensembl:ENST00000621158(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0070278"(extracellular matrix constituent secretion)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029805|mint:Q96BA8|reactome:R-HSA-8874211|refseq:NP_443086.1	refseq:NP_012225.1|sgd:S000001301|mint:P40533|dip:DIP-4575N|ensemblfungi:YIL039W(gene)|ensemblfungi:YIL039W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006506"(GPI anchor biosynthetic process)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016787"(hydrolase activity)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR029052|interpro:IPR033307|interpro:IPR033308	-	comment:mint|function:"Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE"	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:sMWUFmBeBBCO+T0Y2CuB/un1lBg9606	rogid:/O/7xxWpFv7PwN+keOZRqQQPoFw559292	intact-crc:1788756BC3AB065E|rigid:dPR79iA9fNxkT0y99IcuJJhC1RI	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96BA8	uniprotkb:P53053	intact:EBI-6942903|ensembl:ENSP00000481956|intact:MINT-268046|intact:MINT-8162577|uniprotkb:Q8N2D5|uniprotkb:Q96CP0	intact:EBI-5002|uniprotkb:D6VV71|ensemblfungi:YGL263W	psi-mi:cr3l1_human(display_long)|uniprotkb:CREB3L1(gene name)|psi-mi:CREB3L1(display_short)|uniprotkb:OASIS(gene name synonym)|uniprotkb:PSEC0238(orf name)|uniprotkb:Old astrocyte specifically-induced substance(gene name synonym)	psi-mi:cos12_yeast(display_long)|uniprotkb:COS12(gene name)|psi-mi:COS12(display_short)|uniprotkb:NRC380(orf name)|uniprotkb:YGL263W(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553396|imex:IM-24995-3920	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157613(gene)|ensembl:ENST00000621158(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0070278"(extracellular matrix constituent secretion)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029805|mint:Q96BA8|reactome:R-HSA-8874211|refseq:NP_443086.1	sgd:S000003232|refseq:NP_011251.1|dip:DIP-5034N|mint:P53053|ensemblfungi:YGL263W(gene)|ensemblfungi:YGL263W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005768"(endosome)|go:"GO:0016021"(integral component of membrane)|go:"GO:0043328"(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|interpro:IPR001142(Yeast membrane protein DUP)	-	comment:mint|function:"Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE"	crc64:52F58F4E400CA596	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:sMWUFmBeBBCO+T0Y2CuB/un1lBg9606	rogid:SqJH5ysFjpteLzoBp61CbATkXt8559292	intact-crc:BAA4A21741B42FD1|rigid:IuS4cWZcVak54kXl6gI2iKw9N8U	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96BA8	uniprotkb:P38695	intact:EBI-6942903|ensembl:ENSP00000481956|intact:MINT-268046|intact:MINT-8162577|uniprotkb:Q8N2D5|uniprotkb:Q96CP0	intact:EBI-8778|ensemblfungi:YHR096C|uniprotkb:D3DL46	psi-mi:cr3l1_human(display_long)|uniprotkb:CREB3L1(gene name)|psi-mi:CREB3L1(display_short)|uniprotkb:OASIS(gene name synonym)|uniprotkb:PSEC0238(orf name)|uniprotkb:Old astrocyte specifically-induced substance(gene name synonym)	psi-mi:hxt5_yeast(display_long)|uniprotkb:YHR096C(locus name)|uniprotkb:HXT5(gene name)|psi-mi:HXT5(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553392|imex:IM-24995-3919	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157613(gene)|ensembl:ENST00000621158(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0070278"(extracellular matrix constituent secretion)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029805|mint:Q96BA8|reactome:R-HSA-8874211|refseq:NP_443086.1	ensemblfungi:YHR096C(gene)|ensemblfungi:YHR096C_mRNA(transcript)|go:"GO:0005351"("carbohydrate:proton symporter activity")|go:"GO:0005355"(glucose transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005353"(fructose transmembrane transporter activity)|go:"GO:0008643"(carbohydrate transport)|go:"GO:0008645"(hexose transmembrane transport)|go:"GO:0015578"(mannose transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|go:"GO:1904659"(glucose transmembrane transport)|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259|refseq:NP_011964.1|sgd:S000001138|mint:P38695|dip:DIP-5594N	-	comment:mint|function:"Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE"	crc64:6906721BAC1A5F87	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:sMWUFmBeBBCO+T0Y2CuB/un1lBg9606	rogid:aZGrWmUu+AZ4G6qmTG+Z+p6i7hs559292	intact-crc:C87D2B72E569E9C7|rigid:clZKqOoiykAaQU0HwL5bwgX/Tt0	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96BA8	uniprotkb:P50076	intact:EBI-6942903|ensembl:ENSP00000481956|intact:MINT-268046|intact:MINT-8162577|uniprotkb:Q8N2D5|uniprotkb:Q96CP0	intact:EBI-7301533|intact:UNK-5379069|uniprotkb:D6VV08|ensemblfungi:YGR227W	psi-mi:cr3l1_human(display_long)|uniprotkb:CREB3L1(gene name)|psi-mi:CREB3L1(display_short)|uniprotkb:OASIS(gene name synonym)|uniprotkb:PSEC0238(orf name)|uniprotkb:Old astrocyte specifically-induced substance(gene name synonym)	psi-mi:alg10_yeast(display_long)|uniprotkb:Alpha-1,2-glucosyltransferase ALG10-A(gene name synonym)|uniprotkb:DIE2(gene name)|psi-mi:DIE2(display_short)|uniprotkb:ALG10(gene name synonym)|uniprotkb:G8547(orf name)|uniprotkb:YGR227W(locus name)|uniprotkb:Alpha-2-glucosyltransferase ALG10(gene name synonym)|uniprotkb:Dolichyl-phosphoglucose-dependent glucosyltransferase ALG10(gene name synonym)|uniprotkb:Asparagine-linked glycosylation protein 10(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553380|imex:IM-24995-3916	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157613(gene)|ensembl:ENST00000621158(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0070278"(extracellular matrix constituent secretion)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029805|mint:Q96BA8|reactome:R-HSA-8874211|refseq:NP_443086.1	sgd:S000003459|refseq:NP_011743.2|interpro:IPR016900(Alpha-1, 2 glucosyltransferase Alg10)|ensemblfungi:YGR227W(gene)|ensemblfungi:YGR227W_mRNA(transcript)|go:"GO:0004583"(dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0006488"(dolichol-linked oligosaccharide biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|go:"GO:0106073"(dolichyl pyrophosphate Glc2Man9GlcNAc2 alpha-1,2-glucosyltransferase activity)	-	comment:mint|function:"Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE"	comment:mint|function:"Adds the third glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation. Transfers glucose from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide Glc(2)Man(9)GlcNAc(2)-PP-Dol"	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:sMWUFmBeBBCO+T0Y2CuB/un1lBg9606	rogid:CgcGK+aNZdx786YvH8/CbJHTirw559292	intact-crc:A6955DEFCC1DA081|rigid:tBHOTfqU6XaQ5rubwjPCIwnswLA	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96BA8	uniprotkb:P25619	intact:EBI-6942903|ensembl:ENSP00000481956|intact:MINT-268046|intact:MINT-8162577|uniprotkb:Q8N2D5|uniprotkb:Q96CP0	intact:EBI-8563|uniprotkb:Q04556|uniprotkb:D6VR31|ensemblfungi:YCR021C	psi-mi:cr3l1_human(display_long)|uniprotkb:CREB3L1(gene name)|psi-mi:CREB3L1(display_short)|uniprotkb:OASIS(gene name synonym)|uniprotkb:PSEC0238(orf name)|uniprotkb:Old astrocyte specifically-induced substance(gene name synonym)	psi-mi:hsp30_yeast(display_long)|uniprotkb:YCR21C(orf name)|uniprotkb:YCR021C(locus name)|uniprotkb:HSP30(gene name)|psi-mi:HSP30(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553384|imex:IM-24995-3917	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157613(gene)|ensembl:ENST00000621158(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0070278"(extracellular matrix constituent secretion)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029805|mint:Q96BA8|reactome:R-HSA-8874211|refseq:NP_443086.1	refseq:NP_009950.1|sgd:S000000615|mint:P25619|dip:DIP-4586N|ensemblfungi:YCR021C(gene)|ensemblfungi:YCR021C_mRNA(transcript)|go:"GO:0005216"(ion channel activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0034605"(cellular response to heat)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0071470"(cellular response to osmotic stress)|interpro:IPR001425(Rhodopsin, bacterial)|interpro:IPR043476	-	comment:mint|function:"Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE"	crc64:260474A481D29AC5	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:sMWUFmBeBBCO+T0Y2CuB/un1lBg9606	rogid:hkFai3t0xeh5wGaj/RAYUfPwoPw559292	intact-crc:0EC2CEE69627BE94|rigid:67qn36GAPcksjVg01uLfF9E88fk	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96BA8	uniprotkb:P38894	intact:EBI-6942903|ensembl:ENSP00000481956|intact:MINT-268046|intact:MINT-8162577|uniprotkb:Q8N2D5|uniprotkb:Q96CP0	intact:EBI-6990|uniprotkb:D3DLG0|ensemblfungi:YHR211W	psi-mi:cr3l1_human(display_long)|uniprotkb:CREB3L1(gene name)|psi-mi:CREB3L1(display_short)|uniprotkb:OASIS(gene name synonym)|uniprotkb:PSEC0238(orf name)|uniprotkb:Old astrocyte specifically-induced substance(gene name synonym)	psi-mi:flo5_yeast(display_long)|uniprotkb:YHR211W(locus name)|uniprotkb:FLO5(gene name)|psi-mi:FLO5(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553388|imex:IM-24995-3918	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157613(gene)|ensembl:ENST00000621158(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0070278"(extracellular matrix constituent secretion)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029805|mint:Q96BA8|reactome:R-HSA-8874211|refseq:NP_443086.1	refseq:NP_012081.1|sgd:S000001254|dip:DIP-4056N|ensemblfungi:YHR211W(gene)|ensemblfungi:YHR211W_mRNA(transcript)|go:"GO:0000128"(flocculation)|go:"GO:0005537"(mannose binding)|go:"GO:0005576"(extracellular region)|go:"GO:0009277"(fungal-type cell wall)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0031589"(cell-substrate adhesion)|go:"GO:0071944"(cell periphery)|interpro:IPR001389(Flocculin)|interpro:IPR011658(PA14)|interpro:IPR025928|interpro:IPR037524|rcsb pdb:2XJP|rcsb pdb:2XJQ|rcsb pdb:2XJR|rcsb pdb:2XJS|rcsb pdb:2XJT|rcsb pdb:2XJU|rcsb pdb:2XJV|rcsb pdb:4AHW|rcsb pdb:4AHX|rcsb pdb:4AHY|rcsb pdb:4AHZ|rcsb pdb:4AI0|rcsb pdb:4AI1|rcsb pdb:4AI2|rcsb pdb:4AI3	-	comment:mint|function:"Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE"	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:sMWUFmBeBBCO+T0Y2CuB/un1lBg9606	rogid:kWs25Mzne+np7M/ebYwa4Fg1yqg559292	intact-crc:6C3F80B138DEE5EC|rigid:6ICkyyI0yZYCyTwytnUg3TaeUrA	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96BA8	uniprotkb:Q12746	intact:EBI-6942903|ensembl:ENSP00000481956|intact:MINT-268046|intact:MINT-8162577|uniprotkb:Q8N2D5|uniprotkb:Q96CP0	intact:EBI-27973|uniprotkb:D6W0G0|ensemblfungi:YML125C	psi-mi:cr3l1_human(display_long)|uniprotkb:CREB3L1(gene name)|psi-mi:CREB3L1(display_short)|uniprotkb:OASIS(gene name synonym)|uniprotkb:PSEC0238(orf name)|uniprotkb:Old astrocyte specifically-induced substance(gene name synonym)	psi-mi:pga3_yeast(display_long)|uniprotkb:YML125C(locus name)|uniprotkb:YM4987.10C(orf name)|uniprotkb:YM7056.01C(orf name)|uniprotkb:PGA3(gene name)|psi-mi:PGA3(display_short)|uniprotkb:NQR1(gene name synonym)|uniprotkb:Processing of GAS1 and ALP protein 3(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553416|imex:IM-24995-3925	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157613(gene)|ensembl:ENST00000621158(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0070278"(extracellular matrix constituent secretion)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029805|mint:Q96BA8|reactome:R-HSA-8874211|refseq:NP_443086.1	refseq:NP_013581.1|sgd:S000004594|dip:DIP-4519N|ensemblfungi:YML125C(gene)|ensemblfungi:YML125C_mRNA(transcript)|go:"GO:0004128"("cytochrome-b5 reductase activity, acting on NAD(P)H")|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|interpro:IPR001433("Oxidoreductase FAD/NAD(P)-binding")|interpro:IPR001709(Flavoprotein pyridine nucleotide cytochrome reductase)|interpro:IPR001834("NADH:cytochrome b5 reductase (CBR)")|interpro:IPR008333(Oxidoreductase FAD-binding region)|interpro:IPR017927|interpro:IPR017938|interpro:IPR039261	-	comment:mint|function:"Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE"	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:sMWUFmBeBBCO+T0Y2CuB/un1lBg9606	rogid:+YTQtKGq+TXHYomne3IHzSiugt4559292	intact-crc:42A27AEAE44A4060|rigid:s6UzOJF+NDIejfkL7xf1IporXzc	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96BA8	uniprotkb:P52870	intact:EBI-6942903|ensembl:ENSP00000481956|intact:MINT-268046|intact:MINT-8162577|uniprotkb:Q8N2D5|uniprotkb:Q96CP0	intact:EBI-16410|ensemblfungi:YER087C-B|uniprotkb:D3DLZ4	psi-mi:cr3l1_human(display_long)|uniprotkb:CREB3L1(gene name)|psi-mi:CREB3L1(display_short)|uniprotkb:OASIS(gene name synonym)|uniprotkb:PSEC0238(orf name)|uniprotkb:Old astrocyte specifically-induced substance(gene name synonym)	psi-mi:sc6b1_yeast(display_long)|uniprotkb:Sec61 complex subunit SBH1(gene name synonym)|uniprotkb:YER087BC(orf name)|uniprotkb:YER087C-B(locus name)|uniprotkb:SBH1(gene name)|psi-mi:SBH1(display_short)|uniprotkb:SEB1(gene name synonym)|uniprotkb:Sec61 complex subunit beta(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553412|imex:IM-24995-3924	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157613(gene)|ensembl:ENST00000621158(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0070278"(extracellular matrix constituent secretion)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029805|mint:Q96BA8|reactome:R-HSA-8874211|refseq:NP_443086.1	ensemblfungi:YER087C-B(gene)|ensemblfungi:YER087C-B_mRNA(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|interpro:IPR016482(Preprotein translocase Sec, Sec61-beta subunit, eukarya)|interpro:IPR030671|rcsb pdb:6N3Q|rcsb pdb:6ND1|rcsb pdb:7AFT|rcsb pdb:7KAH|rcsb pdb:7KAI|sgd:S000002128|rcsb pdb:7KAJ|rcsb pdb:7KAO|rcsb pdb:7KAP|rcsb pdb:7KAQ|rcsb pdb:7KAR|rcsb pdb:7KAS|rcsb pdb:7KAT|rcsb pdb:7KAU|rcsb pdb:7KB5|refseq:NP_011011.3|dip:DIP-5681N|mint:P52870	-	comment:mint|function:"Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE"	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:sMWUFmBeBBCO+T0Y2CuB/un1lBg9606	rogid:9cYnDPhmMpAOdB2GV5TxikzpjI0559292	intact-crc:ECF18BD41581F23D|rigid:JJlwOt6m3hesNRsZyg8xVuaOAKY	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96BA8	uniprotkb:P40260	intact:EBI-6942903|ensembl:ENSP00000481956|intact:MINT-268046|intact:MINT-8162577|uniprotkb:Q8N2D5|uniprotkb:Q96CP0	intact:EBI-10714|ensemblfungi:YGR121C|uniprotkb:D6VUQ2	psi-mi:cr3l1_human(display_long)|uniprotkb:CREB3L1(gene name)|psi-mi:CREB3L1(display_short)|uniprotkb:OASIS(gene name synonym)|uniprotkb:PSEC0238(orf name)|uniprotkb:Old astrocyte specifically-induced substance(gene name synonym)	psi-mi:mep1_yeast(display_long)|uniprotkb:MEP1(gene name)|psi-mi:MEP1(display_short)|uniprotkb:YGR121C(locus name)|uniprotkb:G6331(orf name)|uniprotkb:AMT1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553400|imex:IM-24995-3921	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157613(gene)|ensembl:ENST00000621158(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0070278"(extracellular matrix constituent secretion)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029805|mint:Q96BA8|reactome:R-HSA-8874211|refseq:NP_443086.1	ensemblfungi:YGR121C(gene)|ensemblfungi:YGR121C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008519"(ammonium transmembrane transporter activity)|go:"GO:0015696"|go:"GO:0019740"(nitrogen utilization)|interpro:IPR001905(Ammonium transporter)|interpro:IPR018047|interpro:IPR024041|interpro:IPR029020|sgd:S000003353|refseq:NP_011636.3|mint:P40260|dip:DIP-5530N	-	comment:mint|function:"Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE"	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:sMWUFmBeBBCO+T0Y2CuB/un1lBg9606	rogid:VnoBl5jhQD24N0SbCLv68HCwl1U559292	intact-crc:E9BBE5199ED1C33E|rigid:ZKdgQdgjnCX7kncCJGtxbUP2YH8	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96BA8	uniprotkb:Q02774	intact:EBI-6942903|ensembl:ENSP00000481956|intact:MINT-268046|intact:MINT-8162577|uniprotkb:Q8N2D5|uniprotkb:Q96CP0	intact:EBI-17099|uniprotkb:Q12413|ensemblfungi:YDL212W|uniprotkb:D6VRE2	psi-mi:cr3l1_human(display_long)|uniprotkb:CREB3L1(gene name)|psi-mi:CREB3L1(display_short)|uniprotkb:OASIS(gene name synonym)|uniprotkb:PSEC0238(orf name)|uniprotkb:Old astrocyte specifically-induced substance(gene name synonym)	psi-mi:shr3_yeast(display_long)|uniprotkb:D1022(orf name)|uniprotkb:YDL212W(locus name)|uniprotkb:SHR3(gene name)|psi-mi:SHR3(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553404|imex:IM-24995-3922	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157613(gene)|ensembl:ENST00000621158(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0070278"(extracellular matrix constituent secretion)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029805|mint:Q96BA8|reactome:R-HSA-8874211|refseq:NP_443086.1	refseq:NP_010069.1|sgd:S000002371|ensemblfungi:YDL212W(gene)|ensemblfungi:YDL212W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006457"(protein folding)|go:"GO:0006865"(amino acid transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0015031"(protein transport)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0043332"(mating projection tip)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0090114"(COPII-coated vesicle budding)|interpro:IPR013248(Shr3 amino acid permease chaperone)|dip:DIP-1615N|mint:Q02774	-	comment:mint|function:"Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE"	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:sMWUFmBeBBCO+T0Y2CuB/un1lBg9606	rogid:IGYbkr6cAVoYYx9LhZxB/B9Onnc559292	intact-crc:B738795CF021D340|rigid:UDV0bPWPNi4/8lKzGW+XAxfEZNg	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96BA8	uniprotkb:P40074	intact:EBI-6942903|ensembl:ENSP00000481956|intact:MINT-268046|intact:MINT-8162577|uniprotkb:Q8N2D5|uniprotkb:Q96CP0	intact:EBI-22666|uniprotkb:D3DM25|ensemblfungi:YER119C	psi-mi:cr3l1_human(display_long)|uniprotkb:CREB3L1(gene name)|psi-mi:CREB3L1(display_short)|uniprotkb:OASIS(gene name synonym)|uniprotkb:PSEC0238(orf name)|uniprotkb:Old astrocyte specifically-induced substance(gene name synonym)	psi-mi:avt6_yeast(display_long)|uniprotkb:YER119C(locus name)|uniprotkb:AVT6(gene name)|psi-mi:AVT6(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553408|imex:IM-24995-3923	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157613(gene)|ensembl:ENST00000621158(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0070278"(extracellular matrix constituent secretion)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029805|mint:Q96BA8|reactome:R-HSA-8874211|refseq:NP_443086.1	refseq:NP_011044.1|sgd:S000000921|dip:DIP-4489N|ensemblfungi:YER119C(gene)|ensemblfungi:YER119C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0003333"(amino acid transmembrane transport)|go:"GO:0005290"(L-histidine transmembrane transporter activity)|go:"GO:0005302"(L-tyrosine transmembrane transporter activity)|go:"GO:0005313"(L-glutamate transmembrane transporter activity)|go:"GO:0015171"(amino acid transmembrane transporter activity)|go:"GO:0015183"(L-aspartate transmembrane transporter activity)|go:"GO:0015189"(L-lysine transmembrane transporter activity)|go:"GO:0015194"(L-serine transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032974"(amino acid transmembrane export from vacuole)|go:"GO:0055085"(transmembrane transport)|go:"GO:0061459"(L-arginine transmembrane transporter activity)|interpro:IPR013057(Amino acid transporter, transmembrane)	-	comment:mint|function:"Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE"	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:sMWUFmBeBBCO+T0Y2CuB/un1lBg9606	rogid:KSuV+ucakPCtl1xQLMI6W54S7r0559292	intact-crc:7CE0AA69A6C69B80|rigid:ejPtOwiLtFx+6GXyn4cOSdiuTUg	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P36118	uniprotkb:Q96BD8	intact:EBI-26362|uniprotkb:D6VX87|ensemblfungi:YKR022C	intact:EBI-741854|uniprotkb:B2R9Y6|uniprotkb:B4E0P4|ensembl:ENSP00000285116|ensembl:ENSP00000381470|ensembl:ENSP00000458992|ensembl:ENSP00000478259	psi-mi:ntr2_yeast(display_long)|uniprotkb:YKR022C(locus name)|uniprotkb:Nineteen complex-related protein 2(gene name synonym)|uniprotkb:NTR2(gene name)|psi-mi:NTR2(display_short)	psi-mi:ska1_human(display_long)|uniprotkb:SKA1(gene name)|psi-mi:SKA1(display_short)|uniprotkb:C18orf24(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553432|imex:IM-24995-3929	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000001730|refseq:NP_012947.1|mint:P36118|dip:DIP-1924N|ensemblfungi:YKR022C(gene)|ensemblfungi:YKR022C_mRNA(transcript)|go:"GO:0000390"(spliceosomal complex disassembly)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0071008"(U2-type post-mRNA release spliceosomal complex)|interpro:IPR028211|rcsb pdb:5Y88	refseq:NP_001034624.1|refseq:NP_659497.1|ensembl:ENSG00000154839(gene)|ensembl:ENSG00000262634(gene)|ensembl:ENST00000285116(transcript)|ensembl:ENST00000398452(transcript)|ensembl:ENST00000571751(transcript)|ensembl:ENST00000616604(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000940"(outer kinetochore)|go:"GO:0005829"(cytosol)|go:"GO:0005876"(spindle microtubule)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008017"(microtubule binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0031110"(regulation of microtubule polymerization or depolymerization)|go:"GO:0051301"(cell division)|go:"GO:0072686"(mitotic spindle)|interpro:IPR009829(Protein of unknown function DUF1395)|interpro:IPR042031|mint:Q96BD8|rcsb pdb:4AJ5|rcsb pdb:4C9Y|rcsb pdb:4CA0|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:q7LBRp/vP0mdE4MGFfqW71T1LQg559292	rogid:Z7y57MeLsUJK0R9JNqHJNBbKr/89606	intact-crc:6F3342EE99DEAE4E|rigid:aA8MCdVRwzodM3hsX3LdAXASxss	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96BA8	uniprotkb:P38775	intact:EBI-6942903|ensembl:ENSP00000481956|intact:MINT-268046|intact:MINT-8162577|uniprotkb:Q8N2D5|uniprotkb:Q96CP0	intact:EBI-24520|uniprotkb:D3DKZ3|ensemblfungi:YHR045W	psi-mi:cr3l1_human(display_long)|uniprotkb:CREB3L1(gene name)|psi-mi:CREB3L1(display_short)|uniprotkb:OASIS(gene name synonym)|uniprotkb:PSEC0238(orf name)|uniprotkb:Old astrocyte specifically-induced substance(gene name synonym)	psi-mi:yhk5_yeast(display_long)|uniprotkb:YHR045W(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553420|imex:IM-24995-3926	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157613(gene)|ensembl:ENST00000621158(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0070278"(extracellular matrix constituent secretion)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029805|mint:Q96BA8|reactome:R-HSA-8874211|refseq:NP_443086.1	sgd:S000001087|refseq:NP_011911.1|dip:DIP-5587N|mint:P38775|ensemblfungi:YHR045W(gene)|ensemblfungi:YHR045W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0016021"(integral component of membrane)	-	comment:mint|function:"Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE"	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:sMWUFmBeBBCO+T0Y2CuB/un1lBg9606	rogid:DIfjsK4iO1b4tmBBj9gsbfGBAoE559292	intact-crc:F821C678C3394231|rigid:AlqmBVYU0BvJlGUq9nEYs5yqXZI	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96BA8	uniprotkb:P47124	intact:EBI-6942903|ensembl:ENSP00000481956|intact:MINT-268046|intact:MINT-8162577|uniprotkb:Q8N2D5|uniprotkb:Q96CP0	intact:EBI-8430|uniprotkb:E9P8X6|uniprotkb:D6VWP5|ensemblfungi:YJR075W	psi-mi:cr3l1_human(display_long)|uniprotkb:CREB3L1(gene name)|psi-mi:CREB3L1(display_short)|uniprotkb:OASIS(gene name synonym)|uniprotkb:PSEC0238(orf name)|uniprotkb:Old astrocyte specifically-induced substance(gene name synonym)	psi-mi:hoc1_yeast(display_long)|uniprotkb:HOC1(gene name)|psi-mi:HOC1(display_short)|uniprotkb:YJR075W(locus name)|uniprotkb:J1830(orf name)|uniprotkb:Mannan polymerase II complex HOC1 subunit(gene name synonym)|uniprotkb:M-Pol II subunit Hoc1p(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553424|imex:IM-24995-3927	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157613(gene)|ensembl:ENST00000621158(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0070278"(extracellular matrix constituent secretion)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029805|mint:Q96BA8|reactome:R-HSA-8874211|refseq:NP_443086.1	sgd:S000003836|refseq:NP_012609.3|dip:DIP-918N|ensemblfungi:YJR075W(gene)|ensemblfungi:YJR075W_mRNA(transcript)|go:"GO:0000009"(alpha-1,6-mannosyltransferase activity)|go:"GO:0000032"(cell wall mannoprotein biosynthetic process)|go:"GO:0000136"(mannan polymerase complex)|go:"GO:0006080"(substituted mannan metabolic process)|go:"GO:0006491"(N-glycan processing)|interpro:IPR007577(Glycosyltransferase sugar-binding region containing DXD motif)|interpro:IPR029044|interpro:IPR039367	-	comment:mint|function:"Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE"	crc64:8BF77385510DE6B0	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:sMWUFmBeBBCO+T0Y2CuB/un1lBg9606	rogid:wfRzXnEiSgEJNFaUo37t6GRAYmY559292	intact-crc:388330F68F81959C|rigid:6zFeAftRsIp5f5CsGelMlyM8KK0	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96BA8	uniprotkb:P47155	intact:EBI-6942903|ensembl:ENSP00000481956|intact:MINT-268046|intact:MINT-8162577|uniprotkb:Q8N2D5|uniprotkb:Q96CP0	intact:EBI-2051644|uniprotkb:D6VWT7|ensemblfungi:YJR118C	psi-mi:cr3l1_human(display_long)|uniprotkb:CREB3L1(gene name)|psi-mi:CREB3L1(display_short)|uniprotkb:OASIS(gene name synonym)|uniprotkb:PSEC0238(orf name)|uniprotkb:Old astrocyte specifically-induced substance(gene name synonym)	psi-mi:ilm1_yeast(display_long)|uniprotkb:Increased loss of mitochondrial DNA protein 1(gene name synonym)|uniprotkb:J2033(orf name)|uniprotkb:ILM1(gene name)|psi-mi:ILM1(display_short)|uniprotkb:YJR118C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553428|imex:IM-24995-3928	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157613(gene)|ensembl:ENST00000621158(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0070278"(extracellular matrix constituent secretion)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029805|mint:Q96BA8|reactome:R-HSA-8874211|refseq:NP_443086.1	sgd:S000003879|interpro:IPR018815|refseq:NP_012652.3|mint:P47155|ensemblfungi:YJR118C(gene)|ensemblfungi:YJR118C_mRNA(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)	-	comment:mint|function:"Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE"	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:sMWUFmBeBBCO+T0Y2CuB/un1lBg9606	rogid:BrQhbXGvUjNG6Bt5c0J7T8qzMeI559292	intact-crc:E444113D065E6042|rigid:lCg7wDQ2zuSIP1rO0i23xqrT9Zg	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96BR9	uniprotkb:P25372	intact:EBI-742740|uniprotkb:Q8IUL5|uniprotkb:Q8IWR9|uniprotkb:Q8N2Y5|uniprotkb:Q96BX0|ensembl:ENSP00000362609	intact:EBI-19616|uniprotkb:D6VR84|ensemblfungi:YCR083W	psi-mi:zbt8a_human(display_long)|uniprotkb:ZBTB8A(gene name)|psi-mi:ZBTB8A(display_short)|uniprotkb:BOZF1(gene name synonym)|uniprotkb:BTB/POZ and zinc-finger domain-containing factor(gene name synonym)|uniprotkb:BTB/POZ and zinc-finger domains factor on chromosome 1(gene name synonym)	psi-mi:trx3_yeast(display_long)|uniprotkb:TRX3(gene name)|psi-mi:TRX3(display_short)|uniprotkb:YCR83W(orf name)|uniprotkb:YCR083W(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553448|imex:IM-24995-3933	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000160062(gene)|ensembl:ENST00000373510(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|refseq:NP_001035531.2|refseq:NP_001278425.1	interpro:IPR036249|refseq:NP_010006.1|sgd:S000000679|interpro:IPR017937|interpro:IPR013766(Thioredoxin domain)|rcsb pdb:2OE0|rcsb pdb:2OE1|rcsb pdb:2OE3|ensemblfungi:YCR083W(gene)|ensemblfungi:YCR083W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0015036"(disulfide oxidoreductase activity)|go:"GO:0034599"(cellular response to oxidative stress)|rcsb pdb:5YKW	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:tsrPT2tHvuBryODKgRXnceXz9s09606	rogid:g0xjGf9GvJRl8iv2qoT5tOs7jXI559292	intact-crc:DEC8D2B2F325F707|rigid:53vtLDth6ciX/tVN2LjZ7vKzi6s	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P48232	uniprotkb:Q96BD8	intact:EBI-28775|uniprotkb:D6W193|ensemblfungi:YNL086W	intact:EBI-741854|uniprotkb:B2R9Y6|uniprotkb:B4E0P4|ensembl:ENSP00000285116|ensembl:ENSP00000381470|ensembl:ENSP00000458992|ensembl:ENSP00000478259	psi-mi:snapn_yeast(display_long)|uniprotkb:YNL086W(locus name)|uniprotkb:N2254(orf name)|uniprotkb:SNN1(gene name)|psi-mi:SNN1(display_short)|uniprotkb:SNAPIN-like protein 1(gene name synonym)	psi-mi:ska1_human(display_long)|uniprotkb:SKA1(gene name)|psi-mi:SKA1(display_short)|uniprotkb:C18orf24(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553436|imex:IM-24995-3930	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014313.1|sgd:S000005030|dip:DIP-1188N|mint:P48232|ensemblfungi:YNL086W(gene)|ensemblfungi:YNL086W_mRNA(transcript)|go:"GO:0005768"(endosome)|go:"GO:0007032"(endosome organization)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0032880"(regulation of protein localization)	refseq:NP_001034624.1|refseq:NP_659497.1|ensembl:ENSG00000154839(gene)|ensembl:ENSG00000262634(gene)|ensembl:ENST00000285116(transcript)|ensembl:ENST00000398452(transcript)|ensembl:ENST00000571751(transcript)|ensembl:ENST00000616604(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000940"(outer kinetochore)|go:"GO:0005829"(cytosol)|go:"GO:0005876"(spindle microtubule)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008017"(microtubule binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0031110"(regulation of microtubule polymerization or depolymerization)|go:"GO:0051301"(cell division)|go:"GO:0072686"(mitotic spindle)|interpro:IPR009829(Protein of unknown function DUF1395)|interpro:IPR042031|mint:Q96BD8|rcsb pdb:4AJ5|rcsb pdb:4C9Y|rcsb pdb:4CA0|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025	-	crc64:33200D2F0F729DA1	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:XCPaHuGC9oKD/3W0gY5ZY8jKtFs559292	rogid:Z7y57MeLsUJK0R9JNqHJNBbKr/89606	intact-crc:4838FFCA68DCF172|rigid:UB/Bin/IhLlBAU8regFNV3ErgzA	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q06132	uniprotkb:Q96BR9	intact:EBI-34377|uniprotkb:D6VYX6|ensemblfungi:YLR336C	intact:EBI-742740|uniprotkb:Q8IUL5|uniprotkb:Q8IWR9|uniprotkb:Q8N2Y5|uniprotkb:Q96BX0|ensembl:ENSP00000362609	psi-mi:sgd1_yeast(display_long)|uniprotkb:SGD1(gene name)|psi-mi:SGD1(display_short)|uniprotkb:YLR336C(locus name)	psi-mi:zbt8a_human(display_long)|uniprotkb:ZBTB8A(gene name)|psi-mi:ZBTB8A(display_short)|uniprotkb:BOZF1(gene name synonym)|uniprotkb:BTB/POZ and zinc-finger domain-containing factor(gene name synonym)|uniprotkb:BTB/POZ and zinc-finger domains factor on chromosome 1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553440|imex:IM-24995-3931	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013440.1|sgd:S000004328|mint:Q06132|dip:DIP-6333N|ensemblfungi:YLR336C(gene)|ensemblfungi:YLR336C_mRNA(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0006972"(hyperosmotic response)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0097078"(FAL1-SGD1 complex)|interpro:IPR003890(MIF4G-like, type 3)|interpro:IPR003891(Initiation factor eIF-4 gamma, MA3)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR016024(Armadillo-type fold)	ensembl:ENSG00000160062(gene)|ensembl:ENST00000373510(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|refseq:NP_001035531.2|refseq:NP_001278425.1	-	crc64:8EEFDB8258407FF3	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:FxZCxGejbcvEs/J2h1HEaWeVZLQ559292	rogid:tsrPT2tHvuBryODKgRXnceXz9s09606	intact-crc:87BC818258DCC138|rigid:OrBST+5s2tv+JURxyCkkkwDRIBs	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P36009	uniprotkb:Q96BR9	intact:EBI-5844|ensemblfungi:YKL078W|uniprotkb:Q07040|uniprotkb:D6VXK9	intact:EBI-742740|uniprotkb:Q8IUL5|uniprotkb:Q8IWR9|uniprotkb:Q8N2Y5|uniprotkb:Q96BX0|ensembl:ENSP00000362609	psi-mi:dhr2_yeast(display_long)|uniprotkb:DHR2(gene name)|psi-mi:DHR2(display_short)|uniprotkb:YKL078W(locus name)|uniprotkb:YKL408(orf name)|uniprotkb:DEAH box RNA helicase DHR2(gene name synonym)|uniprotkb:Helicase JA2(gene name synonym)	psi-mi:zbt8a_human(display_long)|uniprotkb:ZBTB8A(gene name)|psi-mi:ZBTB8A(display_short)|uniprotkb:BOZF1(gene name synonym)|uniprotkb:BTB/POZ and zinc-finger domain-containing factor(gene name synonym)|uniprotkb:BTB/POZ and zinc-finger domains factor on chromosome 1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553444|imex:IM-24995-3932	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YKL078W(gene)|ensemblfungi:YKL078W_mRNA(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|refseq:NP_012845.1|sgd:S000001561|dip:DIP-6424N|mint:P36009|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417	ensembl:ENSG00000160062(gene)|ensembl:ENST00000373510(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|refseq:NP_001035531.2|refseq:NP_001278425.1	-	crc64:AAFA78B5F6215D89	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:UneKv9+4eIsC09fOzm8AvKCOCVs559292	rogid:tsrPT2tHvuBryODKgRXnceXz9s09606	intact-crc:B76D26FE63887F1D|rigid:WbBEdlgDyAgMyDVt3Br/S+A2t+E	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P38340	uniprotkb:Q96BR9	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-742740|uniprotkb:Q8IUL5|uniprotkb:Q8IWR9|uniprotkb:Q8N2Y5|uniprotkb:Q96BX0|ensembl:ENSP00000362609	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:zbt8a_human(display_long)|uniprotkb:ZBTB8A(gene name)|psi-mi:ZBTB8A(display_short)|uniprotkb:BOZF1(gene name synonym)|uniprotkb:BTB/POZ and zinc-finger domain-containing factor(gene name synonym)|uniprotkb:BTB/POZ and zinc-finger domains factor on chromosome 1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553468|imex:IM-24995-3938	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F	ensembl:ENSG00000160062(gene)|ensembl:ENST00000373510(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|refseq:NP_001035531.2|refseq:NP_001278425.1	-	crc64:66699F37B0013088	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:tsrPT2tHvuBryODKgRXnceXz9s09606	intact-crc:ABD84B1DCBB733E5|rigid:DuH/mBVmT+SjtiDNS+xDBvkP3c0	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P39518	uniprotkb:Q96BR9	intact:EBI-10082|uniprotkb:D3DLR3|ensemblfungi:YER015W	intact:EBI-742740|uniprotkb:Q8IUL5|uniprotkb:Q8IWR9|uniprotkb:Q8N2Y5|uniprotkb:Q96BX0|ensembl:ENSP00000362609	psi-mi:lcf2_yeast(display_long)|uniprotkb:YER015W(locus name)|uniprotkb:FAA2(gene name)|psi-mi:FAA2(display_short)|uniprotkb:FAM1(gene name synonym)|uniprotkb:Long-chain acyl-CoA synthetase 2(gene name synonym)|uniprotkb:Fatty acid activator 2(gene name synonym)	psi-mi:zbt8a_human(display_long)|uniprotkb:ZBTB8A(gene name)|psi-mi:ZBTB8A(display_short)|uniprotkb:BOZF1(gene name synonym)|uniprotkb:BTB/POZ and zinc-finger domain-containing factor(gene name synonym)|uniprotkb:BTB/POZ and zinc-finger domains factor on chromosome 1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553464|imex:IM-24995-3937	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000000817|ensemblfungi:YER015W_mRNA(transcript)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0004467"(long-chain fatty acid-CoA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0015910"(long-chain fatty acid import into peroxisome)|go:"GO:0015916"(fatty-acyl-CoA transport)|go:"GO:0016020"(membrane)|go:"GO:0031956"(medium-chain fatty acid-CoA ligase activity)|go:"GO:0031957"(very long-chain fatty acid-CoA ligase activity)|go:"GO:0042760"(very long-chain fatty acid catabolic process)|go:"GO:0102391"(decanoate-CoA ligase activity)|ensemblfungi:YER015W(gene)|interpro:IPR020845|interpro:IPR000873(AMP-dependent synthetase and ligase)|reactome:R-SCE-75876|refseq:NP_010931.3|dip:DIP-6565N	ensembl:ENSG00000160062(gene)|ensembl:ENST00000373510(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|refseq:NP_001035531.2|refseq:NP_001278425.1	-	crc64:1E023C18682805BC	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:N0W+wPvCsl01y0k8hJZ156LztOo559292	rogid:tsrPT2tHvuBryODKgRXnceXz9s09606	intact-crc:35E201268075C531|rigid:Gr/sWGuaQeQTACIYn7TXknaBu6k	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q07732	uniprotkb:Q96BR9	intact:EBI-33406|ensemblfungi:YDL239C|uniprotkb:D6VRB7	intact:EBI-742740|uniprotkb:Q8IUL5|uniprotkb:Q8IWR9|uniprotkb:Q8N2Y5|uniprotkb:Q96BX0|ensembl:ENSP00000362609	psi-mi:ady3_yeast(display_long)|uniprotkb:YDL239C(locus name)|uniprotkb:ADY3(gene name)|psi-mi:ADY3(display_short)	psi-mi:zbt8a_human(display_long)|uniprotkb:ZBTB8A(gene name)|psi-mi:ZBTB8A(display_short)|uniprotkb:BOZF1(gene name synonym)|uniprotkb:BTB/POZ and zinc-finger domain-containing factor(gene name synonym)|uniprotkb:BTB/POZ and zinc-finger domains factor on chromosome 1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553452|imex:IM-24995-3934	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010042.2|sgd:S000002398|ensemblfungi:YDL239C(gene)|ensemblfungi:YDL239C_mRNA(transcript)|go:"GO:0000001"(mitochondrion inheritance)|go:"GO:0005628"(prospore membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0030435"(sporulation resulting in formation of a cellular spore)|go:"GO:0030476"(ascospore wall assembly)|go:"GO:0032120"(ascospore-type prospore membrane formation)|go:"GO:0051301"(cell division)|go:"GO:0070056"(prospore membrane leading edge)|interpro:IPR021750|mint:Q07732|dip:DIP-1811N	ensembl:ENSG00000160062(gene)|ensembl:ENST00000373510(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|refseq:NP_001035531.2|refseq:NP_001278425.1	-	crc64:46F17474F30FD3D9	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Cmac2NLDdbBzVKnJfFricfeeX24559292	rogid:tsrPT2tHvuBryODKgRXnceXz9s09606	intact-crc:DFD6875198BE6F35|rigid:4nDxFkyXOQeI2CPShuXwWPWA6ew	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P32502	uniprotkb:Q96BR9	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	intact:EBI-742740|uniprotkb:Q8IUL5|uniprotkb:Q8IWR9|uniprotkb:Q8N2Y5|uniprotkb:Q96BX0|ensembl:ENSP00000362609	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:zbt8a_human(display_long)|uniprotkb:ZBTB8A(gene name)|psi-mi:ZBTB8A(display_short)|uniprotkb:BOZF1(gene name synonym)|uniprotkb:BTB/POZ and zinc-finger domain-containing factor(gene name synonym)|uniprotkb:BTB/POZ and zinc-finger domains factor on chromosome 1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553456|imex:IM-24995-3935	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731	ensembl:ENSG00000160062(gene)|ensembl:ENST00000373510(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|refseq:NP_001035531.2|refseq:NP_001278425.1	-	crc64:A5409FAF1594854C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	rogid:tsrPT2tHvuBryODKgRXnceXz9s09606	intact-crc:7B84E743F131A156|rigid:pGUYzMu13b6NYTUZKoG4AcVut4o	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96BR9	uniprotkb:P25586	intact:EBI-742740|uniprotkb:Q8IUL5|uniprotkb:Q8IWR9|uniprotkb:Q8N2Y5|uniprotkb:Q96BX0|ensembl:ENSP00000362609	intact:EBI-21773|uniprotkb:D6VQV7|ensemblfungi:YCL059C	psi-mi:zbt8a_human(display_long)|uniprotkb:ZBTB8A(gene name)|psi-mi:ZBTB8A(display_short)|uniprotkb:BOZF1(gene name synonym)|uniprotkb:BTB/POZ and zinc-finger domain-containing factor(gene name synonym)|uniprotkb:BTB/POZ and zinc-finger domains factor on chromosome 1(gene name synonym)	psi-mi:krr1_yeast(display_long)|uniprotkb:KRR1(gene name)|psi-mi:KRR1(display_short)|uniprotkb:KRR-R motif-containing protein 1(gene name synonym)|uniprotkb:Ribosomal RNA assembly protein KRR1(gene name synonym)|uniprotkb:YCL59C(orf name)|uniprotkb:YCL059C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553460|imex:IM-24995-3936	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000160062(gene)|ensembl:ENST00000373510(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|refseq:NP_001035531.2|refseq:NP_001278425.1	refseq:NP_009872.1|sgd:S000000564|mint:P25586|dip:DIP-1408N|ensemblfungi:YCL059C_mRNA(transcript)|go:"GO:0000447"("endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0030686"(90S preribosome)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0032040"(small-subunit processome)|go:"GO:0042274"(ribosomal small subunit biogenesis)|interpro:IPR004087(K Homology)|interpro:IPR024166|interpro:IPR036612|interpro:IPR041174|rcsb pdb:4QMF|rcsb pdb:5WLC|rcsb pdb:5WYJ|rcsb pdb:5WYK|rcsb pdb:6KE6|rcsb pdb:6LQP|rcsb pdb:6LQQ|rcsb pdb:6LQU|rcsb pdb:6ZQA|rcsb pdb:6ZQB|rcsb pdb:6ZQC|rcsb pdb:7AJT|reactome:R-SCE-6791226|ensemblfungi:YCL059C(gene)	-	-	crc64:7A7F964E2C7FD056	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:tsrPT2tHvuBryODKgRXnceXz9s09606	rogid:wveCX/DmVjCNLOIejb/nWbrbX3o559292	intact-crc:E7797A4630330B8F|rigid:14DucJA9ZMk13aDdze4XbiwfpgU	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96C32	uniprotkb:P40325	intact:EBI-745483|ensembl:ENSP00000443053	intact:EBI-23614|uniprotkb:D6VV46|ensemblfungi:YGR268C	psi-mi:q96c32_human(display_long)|uniprotkb:UBC(gene name)|psi-mi:UBC(display_short)	psi-mi:hua1_yeast(display_long)|uniprotkb:HUA1(gene name)|psi-mi:HUA1(display_short)|uniprotkb:YGR268C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553488|imex:IM-24995-3943	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000150991(gene)|ensembl:ENST00000538617(transcript)|interpro:IPR000626(Ubiquitin)|interpro:IPR019954|interpro:IPR019956|interpro:IPR029071	sgd:S000003500|refseq:NP_011784.3|dip:DIP-1987N|ensemblfungi:YGR268C(gene)|ensemblfungi:YGR268C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|interpro:IPR038910	-	-	crc64:78029FD484168793	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:IkHD1AAO/mSSvaZqrZi5tXVfPOw9606	rogid:xliNG9XUWbYRd0Nbu+xzCgxNrAs559292	intact-crc:230F485F88279753|rigid:yFAItV8WCJx6w3KzRXcFvymZeww	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96BR9	uniprotkb:Q03338	intact:EBI-742740|uniprotkb:Q8IUL5|uniprotkb:Q8IWR9|uniprotkb:Q8N2Y5|uniprotkb:Q96BX0|ensembl:ENSP00000362609	intact:EBI-421|uniprotkb:D6VT97|ensemblfungi:YDR473C	psi-mi:zbt8a_human(display_long)|uniprotkb:ZBTB8A(gene name)|psi-mi:ZBTB8A(display_short)|uniprotkb:BOZF1(gene name synonym)|uniprotkb:BTB/POZ and zinc-finger domain-containing factor(gene name synonym)|uniprotkb:BTB/POZ and zinc-finger domains factor on chromosome 1(gene name synonym)	psi-mi:prp3_yeast(display_long)|uniprotkb:PRP3(gene name)|psi-mi:PRP3(display_short)|uniprotkb:RNA3(gene name synonym)|uniprotkb:YDR473C(locus name)|uniprotkb:D8035.16(orf name)|uniprotkb:Pre-mRNA-splicing factor 3(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553484|imex:IM-24995-3942	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000160062(gene)|ensembl:ENST00000373510(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|refseq:NP_001035531.2|refseq:NP_001278425.1	sgd:S000002881|refseq:NP_010761.3|ensemblfungi:YDR473C(gene)|ensemblfungi:YDR473C_mRNA(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|interpro:IPR010541(Protein of unknown function DUF1115)|interpro:IPR013881(Pre-mRNA-splicing factor 3)|interpro:IPR027104|rcsb pdb:3JCM|rcsb pdb:4YHU|rcsb pdb:4YHV|rcsb pdb:4YHW|rcsb pdb:5GAN|rcsb pdb:5GAP|rcsb pdb:5NRL|rcsb pdb:5ZWM|rcsb pdb:5ZWO|dip:DIP-5266N|mint:Q03338	-	-	crc64:E977FD9F708BDD91	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:tsrPT2tHvuBryODKgRXnceXz9s09606	rogid:KE0Y/kRXTq9LXt4PGsKnRcY7Sqg559292	intact-crc:AAFDECAD7642B01E|rigid:IVEbIOp9yqdYWIMXWUGgK0gWKck	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96BR9	uniprotkb:P40482	intact:EBI-742740|uniprotkb:Q8IUL5|uniprotkb:Q8IWR9|uniprotkb:Q8N2Y5|uniprotkb:Q96BX0|ensembl:ENSP00000362609	intact:EBI-16592|ensemblfungi:YIL109C|uniprotkb:D6VVH8	psi-mi:zbt8a_human(display_long)|uniprotkb:ZBTB8A(gene name)|psi-mi:ZBTB8A(display_short)|uniprotkb:BOZF1(gene name synonym)|uniprotkb:BTB/POZ and zinc-finger domain-containing factor(gene name synonym)|uniprotkb:BTB/POZ and zinc-finger domains factor on chromosome 1(gene name synonym)	psi-mi:sec24_yeast(display_long)|uniprotkb:SEC24(gene name)|psi-mi:SEC24(display_short)|uniprotkb:Abnormal nuclear morphology 1(gene name synonym)|uniprotkb:ANU1(gene name synonym)|uniprotkb:YIL109C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553472|imex:IM-24995-3939	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000160062(gene)|ensembl:ENST00000373510(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|refseq:NP_001035531.2|refseq:NP_001278425.1	refseq:NP_012157.3|ensemblfungi:YIL109C(gene)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016236"(macroautophagy)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0070971"(endoplasmic reticulum exit site)|ensemblfungi:YIL109C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0090110"(COPII-coated vesicle cargo loading)|interpro:IPR006895(Zinc finger, Sec23/Sec24-type)|interpro:IPR006896(Sec23/Sec24 trunk region)|interpro:IPR006900(Sec23/Sec24 helical region)|interpro:IPR007123(Gelsolin region)|interpro:IPR012990(Sec23/Sec24 beta-sandwich)|interpro:IPR029006|interpro:IPR036174|interpro:IPR036175|interpro:IPR036180|go:"GO:0000149"(SNARE binding)|go:"GO:0000329"(fungal-type vacuole membrane)|interpro:IPR036465|interpro:IPR041742|rcsb pdb:1M2V|rcsb pdb:1PCX|rcsb pdb:1PD0|rcsb pdb:1PD1|rcsb pdb:4BZI|rcsb pdb:6GNI|rcsb pdb:6ZGA|reactome:R-SCE-204005|reactome:R-SCE-5694530|reactome:R-SCE-983170|go:"GO:0005048"(signal sequence binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|sgd:S000001371|dip:DIP-2233N|mint:P40482	-	-	crc64:35E2BDD24CC75899	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:tsrPT2tHvuBryODKgRXnceXz9s09606	rogid:e7ekVFzZJMZvfRUZ9Q2jDQ/hvs0559292	intact-crc:410C7D996361113A|rigid:TGMPKDd80thAEsAmUjkZybJMmFc	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P12612	uniprotkb:Q96BR9	intact:EBI-19045|uniprotkb:D6VSJ6|ensemblfungi:YDR212W	intact:EBI-742740|uniprotkb:Q8IUL5|uniprotkb:Q8IWR9|uniprotkb:Q8N2Y5|uniprotkb:Q96BX0|ensembl:ENSP00000362609	psi-mi:tcpa_yeast(display_long)|uniprotkb:TCP1(gene name)|psi-mi:TCP1(display_short)|uniprotkb:CCT1(gene name synonym)|uniprotkb:YDR212W(locus name)|uniprotkb:YD8142.13(orf name)|uniprotkb:YD8142B.04(orf name)|uniprotkb:CCT-alpha(gene name synonym)	psi-mi:zbt8a_human(display_long)|uniprotkb:ZBTB8A(gene name)|psi-mi:ZBTB8A(display_short)|uniprotkb:BOZF1(gene name synonym)|uniprotkb:BTB/POZ and zinc-finger domain-containing factor(gene name synonym)|uniprotkb:BTB/POZ and zinc-finger domains factor on chromosome 1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553476|imex:IM-24995-3940	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010498.1|sgd:S000002620|ensemblfungi:YDR212W(gene)|ensemblfungi:YDR212W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012715(T-complex protein 1, alpha subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|rcsb pdb:4V81|rcsb pdb:4V8R|rcsb pdb:4V94|rcsb pdb:5GW4|rcsb pdb:5GW5|rcsb pdb:6KRD|rcsb pdb:6KRE|rcsb pdb:6KS6|rcsb pdb:6KS7|rcsb pdb:6KS8|reactome:R-SCE-390471|reactome:R-SCE-6814122|dip:DIP-2965N|mint:P12612	ensembl:ENSG00000160062(gene)|ensembl:ENST00000373510(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|refseq:NP_001035531.2|refseq:NP_001278425.1	-	crc64:02C625D329359E61	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:xWMsvY106Y6yQ54SOif2UlScafM559292	rogid:tsrPT2tHvuBryODKgRXnceXz9s09606	intact-crc:13DD15D544DA0A05|rigid:eOKcrORbn1aYRa7IKh+kR33ysqI	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96BR9	uniprotkb:Q12259	intact:EBI-742740|uniprotkb:Q8IUL5|uniprotkb:Q8IWR9|uniprotkb:Q8N2Y5|uniprotkb:Q96BX0|ensembl:ENSP00000362609	intact:EBI-30776|uniprotkb:D6VYA8|ensemblfungi:YLR108C	psi-mi:zbt8a_human(display_long)|uniprotkb:ZBTB8A(gene name)|psi-mi:ZBTB8A(display_short)|uniprotkb:BOZF1(gene name synonym)|uniprotkb:BTB/POZ and zinc-finger domain-containing factor(gene name synonym)|uniprotkb:BTB/POZ and zinc-finger domains factor on chromosome 1(gene name synonym)	psi-mi:yl108_yeast(display_long)|uniprotkb:L2913(orf name)|uniprotkb:YLR108C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553480|imex:IM-24995-3941	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000160062(gene)|ensembl:ENST00000373510(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|refseq:NP_001035531.2|refseq:NP_001278425.1	refseq:NP_013209.1|sgd:S000004098|dip:DIP-4075N|ensemblfungi:YLR108C(gene)|ensemblfungi:YLR108C_mRNA(transcript)|go:"GO:0005634"(nucleus)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:tsrPT2tHvuBryODKgRXnceXz9s09606	rogid:CzknxXhhvgMp3J0/oi197EgZ05U559292	intact-crc:73C778AC3F974F11|rigid:be6cdCb6O91+sI6vlgtKlQHNKKQ	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96CG3	uniprotkb:P32502	intact:EBI-740711|ensembl:ENSP00000354911|ensembl:ENSP00000424231	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:tifa_human(display_long)|uniprotkb:Putative NF-kappa-B-activating protein 20(gene name synonym)|uniprotkb:TIFA(gene name)|psi-mi:TIFA(display_short)|uniprotkb:T2BP(gene name synonym)|uniprotkb:TRAF2-binding protein(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM14(gene name synonym)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553504|imex:IM-24995-3947	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_443096.1|ensembl:ENSG00000145365(gene)|ensembl:ENST00000361717(transcript)|ensembl:ENST00000500655(transcript)|go:"GO:0002753"(cytoplasmic pattern recognition receptor signaling pathway)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0051260"(protein homooligomerization)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR033621|rcsb pdb:4YM4|rcsb pdb:4ZGI|rcsb pdb:5ZUJ|rcsb pdb:6A33|reactome:R-HSA-9645460|dip:DIP-40185N	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731	-	-	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:ppKFaTK8YYWSscDQlE1n/mONziY9606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:0F00BDB06F312798|rigid:2KA272tjgq17guvrGjv0gA6SP4E	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P38340	uniprotkb:Q96CD2	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-724333|uniprotkb:Q96SX0|ensembl:ENSP00000343190|uniprotkb:Q9HC17	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:coac_human(display_long)|uniprotkb:CoaC(gene name synonym)|uniprotkb:PPCDC(gene name)|psi-mi:PPCDC(display_short)|uniprotkb:COAC(gene name synonym)|uniprotkb:MDS018(orf name)|uniprotkb:UNQ9365/PRO34154(orf name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553492|imex:IM-24995-3944	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F	refseq:NP_068595.3|rcsb pdb:1QZU|reactome:R-HSA-196783|mint:Q96CD2|ensembl:ENSG00000138621(gene)|ensembl:ENST00000342932(transcript)|go:"GO:0004633"(phosphopantothenoylcysteine decarboxylase activity)|go:"GO:0005829"(cytosol)|go:"GO:0010181"(FMN binding)|go:"GO:0015937"(coenzyme A biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0071513"(phosphopantothenoylcysteine decarboxylase complex)|interpro:IPR003382(Flavoprotein)|interpro:IPR036551|refseq:NP_001288030.1|refseq:NP_001288031.1|refseq:NP_001288032.1|refseq:NP_001288033.1|refseq:NP_001288034.1	-	crc64:66699F37B0013088	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:2d686R1m4jA5uWpf/8O6rI6/Olo9606	intact-crc:A267682F729291D1|rigid:Ie5XThJd1VV+gcdIt5EeSfKwT1g	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q08438	uniprotkb:Q96CD2	intact:EBI-30482|uniprotkb:O00019|uniprotkb:D6W2B8|ensemblfungi:YOR054C	intact:EBI-724333|uniprotkb:Q96SX0|ensembl:ENSP00000343190|uniprotkb:Q9HC17	psi-mi:vhs3_yeast(display_long)|uniprotkb:Viable in a HAL3 SIT4 background protein 3(gene name synonym)|uniprotkb:VHS3(gene name)|psi-mi:VHS3(display_short)|uniprotkb:YOR054C(locus name)|uniprotkb:YOR29-05(orf name)	psi-mi:coac_human(display_long)|uniprotkb:CoaC(gene name synonym)|uniprotkb:PPCDC(gene name)|psi-mi:PPCDC(display_short)|uniprotkb:COAC(gene name synonym)|uniprotkb:MDS018(orf name)|uniprotkb:UNQ9365/PRO34154(orf name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553496|imex:IM-24995-3945	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014697.1|sgd:S000005580|dip:DIP-4172N|mint:Q08438|ensemblfungi:YOR054C(gene)|ensemblfungi:YOR054C_mRNA(transcript)|go:"GO:0003824"(catalytic activity)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0007049"(cell cycle)|go:"GO:0010181"(FMN binding)|go:"GO:0015937"(coenzyme A biosynthetic process)|go:"GO:0030004"(cellular monovalent inorganic cation homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0071513"(phosphopantothenoylcysteine decarboxylase complex)|go:"GO:1990143"(CoA-synthesizing protein complex)|interpro:IPR003382(Flavoprotein)|interpro:IPR036551	refseq:NP_068595.3|rcsb pdb:1QZU|reactome:R-HSA-196783|mint:Q96CD2|ensembl:ENSG00000138621(gene)|ensembl:ENST00000342932(transcript)|go:"GO:0004633"(phosphopantothenoylcysteine decarboxylase activity)|go:"GO:0005829"(cytosol)|go:"GO:0010181"(FMN binding)|go:"GO:0015937"(coenzyme A biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0071513"(phosphopantothenoylcysteine decarboxylase complex)|interpro:IPR003382(Flavoprotein)|interpro:IPR036551|refseq:NP_001288030.1|refseq:NP_001288031.1|refseq:NP_001288032.1|refseq:NP_001288033.1|refseq:NP_001288034.1	-	crc64:A97623473CB6F605	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:xBrkL/88mlDFkk10q3ASQnr0rv0559292	rogid:2d686R1m4jA5uWpf/8O6rI6/Olo9606	intact-crc:6A4DBD7606C4B060|rigid:lDnVx8Qzd0Iw7P3JjS6ee4Lw1FE	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96CD2	uniprotkb:P32502	intact:EBI-724333|uniprotkb:Q96SX0|ensembl:ENSP00000343190|uniprotkb:Q9HC17	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:coac_human(display_long)|uniprotkb:CoaC(gene name synonym)|uniprotkb:PPCDC(gene name)|psi-mi:PPCDC(display_short)|uniprotkb:COAC(gene name synonym)|uniprotkb:MDS018(orf name)|uniprotkb:UNQ9365/PRO34154(orf name)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553500|imex:IM-24995-3946	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_068595.3|rcsb pdb:1QZU|reactome:R-HSA-196783|mint:Q96CD2|ensembl:ENSG00000138621(gene)|ensembl:ENST00000342932(transcript)|go:"GO:0004633"(phosphopantothenoylcysteine decarboxylase activity)|go:"GO:0005829"(cytosol)|go:"GO:0010181"(FMN binding)|go:"GO:0015937"(coenzyme A biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0071513"(phosphopantothenoylcysteine decarboxylase complex)|interpro:IPR003382(Flavoprotein)|interpro:IPR036551|refseq:NP_001288030.1|refseq:NP_001288031.1|refseq:NP_001288032.1|refseq:NP_001288033.1|refseq:NP_001288034.1	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731	-	-	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:2d686R1m4jA5uWpf/8O6rI6/Olo9606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:C58E36B6853DBA4D|rigid:bGg5IRa1rTNv8sVIwXENQbKQ60M	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96CV9	uniprotkb:P40325	intact:EBI-748974|uniprotkb:Q5T672|uniprotkb:Q5T673|uniprotkb:Q5T674|uniprotkb:Q5T675|uniprotkb:Q7LDL9|uniprotkb:Q8N562|uniprotkb:Q9UET9|uniprotkb:Q9UEV4|uniprotkb:Q9Y218|uniprotkb:B3KP00|uniprotkb:D3DRS4|uniprotkb:D3DRS8|ensembl:ENSP00000263036|ensembl:ENSP00000368021|ensembl:ENSP00000368022|ensembl:ENSP00000368032	intact:EBI-23614|uniprotkb:D6VV46|ensemblfungi:YGR268C	psi-mi:optn_human(display_long)|uniprotkb:HYPL(gene name synonym)|uniprotkb:Optic neuropathy-inducing protein(gene name synonym)|uniprotkb:E3-14.7K-interacting protein(gene name synonym)|uniprotkb:FIP-2(gene name synonym)|uniprotkb:Huntingtin-interacting protein L(gene name synonym)|uniprotkb:Huntingtin yeast partner L(gene name synonym)|uniprotkb:NEMO-related protein(gene name synonym)|uniprotkb:Transcription factor IIIA-interacting protein(gene name synonym)|uniprotkb:OPTN(gene name)|psi-mi:OPTN(display_short)|uniprotkb:FIP2(gene name synonym)|uniprotkb:GLC1E(gene name synonym)|uniprotkb:NRP(gene name synonym)|uniprotkb:HIP7(gene name synonym)|uniprotkb:Huntingtin-interacting protein 7(gene name synonym)	psi-mi:hua1_yeast(display_long)|uniprotkb:HUA1(gene name)|psi-mi:HUA1(display_short)|uniprotkb:YGR268C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553524|imex:IM-24995-3952	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001008212.1|refseq:NP_001008213.1|refseq:NP_001008214.1|refseq:NP_068815.2|ensembl:ENSG00000123240(gene)|ensembl:ENST00000263036(transcript)|ensembl:ENST00000378747(transcript)|ensembl:ENST00000378748(transcript)|ensembl:ENST00000378757(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001920"(negative regulation of receptor recycling)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0007030"(Golgi organization)|go:"GO:0007165"(signal transduction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008219"(cell death)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0061734"(parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:1904417"(positive regulation of xenophagy)|interpro:IPR021063|interpro:IPR032419|interpro:IPR032939|interpro:IPR034735|mint:Q96CV9|rcsb pdb:2LO4|rcsb pdb:2LUE|rcsb pdb:3VTV|rcsb pdb:3VTW|rcsb pdb:5AAZ|rcsb pdb:5B83|rcsb pdb:5EOA|rcsb pdb:5EOF|rcsb pdb:7CZM|reactome:R-HSA-2565942|reactome:R-HSA-8854214|dip:DIP-42001N	sgd:S000003500|refseq:NP_011784.3|dip:DIP-1987N|ensemblfungi:YGR268C(gene)|ensemblfungi:YGR268C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|interpro:IPR038910	-	-	crc64:78029FD484168793	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2018/04/06	rogid:jcCTXDx1bJq3K5mgNUD73jeWeBU9606	rogid:xliNG9XUWbYRd0Nbu+xzCgxNrAs559292	intact-crc:2903FF7AF5490995|rigid:XRF29S3IqlMdBF01fxwAe3LRwug	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96CN9	uniprotkb:P31412	intact:EBI-746252|uniprotkb:Q9H6N7|ensembl:ENSP00000318821	intact:EBI-20260|uniprotkb:D6VXK7|ensemblfungi:YKL080W	psi-mi:gcc1_human(display_long)|uniprotkb:Golgi coiled-coil protein 1(gene name synonym)|uniprotkb:GCC1(gene name)|psi-mi:GCC1(display_short)	psi-mi:vatc_yeast(display_long)|uniprotkb:VMA5(gene name)|psi-mi:VMA5(display_short)|uniprotkb:VAT3(gene name synonym)|uniprotkb:VATC(gene name synonym)|uniprotkb:YKL410(orf name)|uniprotkb:YKL080W(locus name)|uniprotkb:Vacuolar proton pump subunit C(gene name synonym)|uniprotkb:V-ATPase 42 kDa subunit(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553520|imex:IM-24995-3951	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_078799.2|ensembl:ENSG00000179562(gene)|ensembl:ENST00000321407(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0031267"(small GTPase binding)|interpro:IPR000237(GRIP)|reactome:R-HSA-6811440|go:"GO:0000138"(Golgi trans cisterna)	refseq:NP_012843.1|sgd:S000001563|ensemblfungi:YKL080W(gene)|ensemblfungi:YKL080W_mRNA(transcript)|go:"GO:0000221"(vacuolar proton-transporting V-type ATPase, V1 domain)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005524"(ATP binding)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|interpro:IPR004907(ATPase, V1 complex, subunit C)|interpro:IPR036132|rcsb pdb:1U7L|rcsb pdb:3J9T|rcsb pdb:3J9U|rcsb pdb:3J9V|rcsb pdb:4DL0|rcsb pdb:4EFA|rcsb pdb:5VOX|rcsb pdb:5VOY|rcsb pdb:5VOZ|rcsb pdb:6O7V|rcsb pdb:6O7W|rcsb pdb:6O7X|reactome:R-SCE-1222556|reactome:R-SCE-77387|reactome:R-SCE-917977|reactome:R-SCE-9639288|dip:DIP-4701N|mint:P31412	-	-	crc64:0CD1B814046C377E	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:SCI+peKjPIvl/HbUUpHGM++qiRE9606	rogid:NBI0upCB5yxAyMQgccBcLhjZk8s559292	intact-crc:2CC480F1C38CBA2B|rigid:RtDrn9y+os/mkYe0mRZfc8/yjS8	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q12083	uniprotkb:Q96CN4	intact:EBI-31634|uniprotkb:D6W3K4|ensemblfungi:YPL164C	intact:EBI-749523|uniprotkb:B9A6I9|ensembl:ENSP00000270530	psi-mi:mlh3_yeast(display_long)|uniprotkb:MLH3(gene name)|psi-mi:MLH3(display_short)|uniprotkb:MutL protein homolog 3(gene name synonym)|uniprotkb:P2550(orf name)|uniprotkb:YPL164C(locus name)	psi-mi:evi5l_human(display_long)|uniprotkb:Ecotropic viral integration site 5-like protein(gene name synonym)|uniprotkb:EVI5L(gene name)|psi-mi:EVI5L(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553508|imex:IM-24995-3948	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015161.1|sgd:S000006085|dip:DIP-2414N|ensemblfungi:YPL164C(gene)|ensemblfungi:YPL164C_mRNA(transcript)|go:"GO:0000710"(meiotic mismatch repair)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006298"(mismatch repair)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0030983"(mismatched DNA binding)|go:"GO:0032300"(mismatch repair complex)|go:"GO:0097587"(MutLgamma complex)|interpro:IPR013507(DNA mismatch repair protein, C-terminal)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR014790(MutL, C-terminal, dimerisation)|interpro:IPR020568|interpro:IPR028830|interpro:IPR036890|interpro:IPR037198|interpro:IPR038973|interpro:IPR042120|rcsb pdb:6RMN|rcsb pdb:6SHX|rcsb pdb:6SNS|rcsb pdb:6SNV	refseq:NP_001153416.1|refseq:NP_660288.1|refseq:XP_005272515.1|refseq:XP_016881728.1|ensembl:ENSG00000142459(gene)|ensembl:ENST00000270530(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0031267"(small GTPase binding)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:1902018"(negative regulation of cilium assembly)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR031214|interpro:IPR035969	-	crc64:970FD7F57EB6E3B1	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:g47/5yM9oWZ13CIZOZ7QT6A+LW0559292	rogid:OKfnOqdRupGBmq6gqoeApO0cgG09606	intact-crc:6BDE2A5358DE7D26|rigid:IqZlr/B4ItdV/mbNSy7C61AoElM	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P53949	uniprotkb:Q96CN4	intact:EBI-28725|uniprotkb:Q6B2U7|uniprotkb:D6W1C2|ensemblfungi:YNL056W	intact:EBI-749523|uniprotkb:B9A6I9|ensembl:ENSP00000270530	psi-mi:oca2_yeast(display_long)|uniprotkb:YNL056W(locus name)|uniprotkb:N2439(orf name)|uniprotkb:YNL2439W(orf name)|uniprotkb:Oxidant-induced cell-cycle arrest protein 2(gene name synonym)|uniprotkb:OCA2(gene name)|psi-mi:OCA2(display_short)	psi-mi:evi5l_human(display_long)|uniprotkb:Ecotropic viral integration site 5-like protein(gene name synonym)|uniprotkb:EVI5L(gene name)|psi-mi:EVI5L(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553512|imex:IM-24995-3949	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005001|refseq:NP_014342.3|dip:DIP-1989N|mint:P53949|ensemblfungi:YNL056W(gene)|ensemblfungi:YNL056W_mRNA(transcript)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005737"(cytoplasm)|interpro:IPR004861(Protein-tyrosine phosphatase, SIW14-like)|interpro:IPR020422|interpro:IPR029021	refseq:NP_001153416.1|refseq:NP_660288.1|refseq:XP_005272515.1|refseq:XP_016881728.1|ensembl:ENSG00000142459(gene)|ensembl:ENST00000270530(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0031267"(small GTPase binding)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:1902018"(negative regulation of cilium assembly)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR031214|interpro:IPR035969	-	crc64:B5CF05FAABD9C236	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:Ydjdu1aqlhPFCckVB/BjaRa1ITI559292	rogid:OKfnOqdRupGBmq6gqoeApO0cgG09606	intact-crc:FE5A45A869A03D6C|rigid:FiiWoxOKb2DhlfBnfPd0ypQsGbc	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96CN9	uniprotkb:Q07732	intact:EBI-746252|uniprotkb:Q9H6N7|ensembl:ENSP00000318821	intact:EBI-33406|ensemblfungi:YDL239C|uniprotkb:D6VRB7	psi-mi:gcc1_human(display_long)|uniprotkb:Golgi coiled-coil protein 1(gene name synonym)|uniprotkb:GCC1(gene name)|psi-mi:GCC1(display_short)	psi-mi:ady3_yeast(display_long)|uniprotkb:YDL239C(locus name)|uniprotkb:ADY3(gene name)|psi-mi:ADY3(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553516|imex:IM-24995-3950	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_078799.2|ensembl:ENSG00000179562(gene)|ensembl:ENST00000321407(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0031267"(small GTPase binding)|interpro:IPR000237(GRIP)|reactome:R-HSA-6811440|go:"GO:0000138"(Golgi trans cisterna)	refseq:NP_010042.2|sgd:S000002398|ensemblfungi:YDL239C(gene)|ensemblfungi:YDL239C_mRNA(transcript)|go:"GO:0000001"(mitochondrion inheritance)|go:"GO:0005628"(prospore membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0030435"(sporulation resulting in formation of a cellular spore)|go:"GO:0030476"(ascospore wall assembly)|go:"GO:0032120"(ascospore-type prospore membrane formation)|go:"GO:0051301"(cell division)|go:"GO:0070056"(prospore membrane leading edge)|interpro:IPR021750|mint:Q07732|dip:DIP-1811N	-	-	crc64:46F17474F30FD3D9	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:SCI+peKjPIvl/HbUUpHGM++qiRE9606	rogid:Cmac2NLDdbBzVKnJfFricfeeX24559292	intact-crc:D78F9D65301DF1B5|rigid:08Jt5ox7qz3ClHaE+1psuSQMvA0	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96CV9	uniprotkb:P40302	intact:EBI-748974|uniprotkb:Q5T672|uniprotkb:Q5T673|uniprotkb:Q5T674|uniprotkb:Q5T675|uniprotkb:Q7LDL9|uniprotkb:Q8N562|uniprotkb:Q9UET9|uniprotkb:Q9UEV4|uniprotkb:Q9Y218|uniprotkb:B3KP00|uniprotkb:D3DRS4|uniprotkb:D3DRS8|ensembl:ENSP00000263036|ensembl:ENSP00000368021|ensembl:ENSP00000368022|ensembl:ENSP00000368032	intact:EBI-13955|ensemblfungi:YMR314W|uniprotkb:D6W0E1	psi-mi:optn_human(display_long)|uniprotkb:HYPL(gene name synonym)|uniprotkb:Optic neuropathy-inducing protein(gene name synonym)|uniprotkb:E3-14.7K-interacting protein(gene name synonym)|uniprotkb:FIP-2(gene name synonym)|uniprotkb:Huntingtin-interacting protein L(gene name synonym)|uniprotkb:Huntingtin yeast partner L(gene name synonym)|uniprotkb:NEMO-related protein(gene name synonym)|uniprotkb:Transcription factor IIIA-interacting protein(gene name synonym)|uniprotkb:OPTN(gene name)|psi-mi:OPTN(display_short)|uniprotkb:FIP2(gene name synonym)|uniprotkb:GLC1E(gene name synonym)|uniprotkb:NRP(gene name synonym)|uniprotkb:HIP7(gene name synonym)|uniprotkb:Huntingtin-interacting protein 7(gene name synonym)	psi-mi:psa6_yeast(display_long)|uniprotkb:PRE5(gene name)|psi-mi:PRE5(display_short)|uniprotkb:YMR314W(locus name)|uniprotkb:YM9924.06(orf name)|uniprotkb:Proteasome component PRE5(gene name synonym)|uniprotkb:Macropain subunit PRE5(gene name synonym)|uniprotkb:Proteinase YSCE subunit PRE5(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit PRE5(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553536|imex:IM-24995-3955	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001008212.1|refseq:NP_001008213.1|refseq:NP_001008214.1|refseq:NP_068815.2|ensembl:ENSG00000123240(gene)|ensembl:ENST00000263036(transcript)|ensembl:ENST00000378747(transcript)|ensembl:ENST00000378748(transcript)|ensembl:ENST00000378757(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001920"(negative regulation of receptor recycling)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0007030"(Golgi organization)|go:"GO:0007165"(signal transduction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008219"(cell death)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0061734"(parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:1904417"(positive regulation of xenophagy)|interpro:IPR021063|interpro:IPR032419|interpro:IPR032939|interpro:IPR034735|mint:Q96CV9|rcsb pdb:2LO4|rcsb pdb:2LUE|rcsb pdb:3VTV|rcsb pdb:3VTW|rcsb pdb:5AAZ|rcsb pdb:5B83|rcsb pdb:5EOA|rcsb pdb:5EOF|rcsb pdb:7CZM|reactome:R-HSA-2565942|reactome:R-HSA-8854214|dip:DIP-42001N	rcsb pdb:4Y8T|rcsb pdb:4Y8U|rcsb pdb:4Y9Y|rcsb pdb:4Y9Z|rcsb pdb:4YA0|rcsb pdb:4YA1|rcsb pdb:4YA2|rcsb pdb:4YA3|rcsb pdb:4YA4|rcsb pdb:4YA5|rcsb pdb:4Y7X|rcsb pdb:4Y7Y|rcsb pdb:4Y80|rcsb pdb:4Y81|rcsb pdb:4Y82|rcsb pdb:4Y84|rcsb pdb:4Y8G|rcsb pdb:4Y8H|rcsb pdb:4Y8I|rcsb pdb:4Y8J|rcsb pdb:4Y8K|rcsb pdb:4Y8L|rcsb pdb:4Y8M|rcsb pdb:4Y8N|rcsb pdb:4Y8O|rcsb pdb:4Y8P|rcsb pdb:4Y8Q|rcsb pdb:4Y8R|rcsb pdb:4Y8S|rcsb pdb:5FG7|rcsb pdb:5FG9|rcsb pdb:5FGA|rcsb pdb:4YA7|rcsb pdb:4YA9|rcsb pdb:4Z1L|rcsb pdb:5A5B|rcsb pdb:5AHJ|rcsb pdb:5BOU|rcsb pdb:5BXL|rcsb pdb:5BXN|rcsb pdb:5CGF|rcsb pdb:5CGG|rcsb pdb:5CGH|rcsb pdb:5CGI|rcsb pdb:5CZ4|rcsb pdb:5CZ5|rcsb pdb:5CZ6|rcsb pdb:5CZ7|rcsb pdb:5CZ8|rcsb pdb:5CZ9|rcsb pdb:5CZA|rcsb pdb:5D0S|rcsb pdb:5D0T|rcsb pdb:5D0V|rcsb pdb:5D0W|rcsb pdb:5D0X|rcsb pdb:5D0Z|rcsb pdb:5DKI|rcsb pdb:5DKJ|rcsb pdb:5FGD|rcsb pdb:3HYE|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:3MG0|rcsb pdb:3MG4|rcsb pdb:3MG6|rcsb pdb:3MG7|rcsb pdb:3MG8|rcsb pdb:3NZJ|rcsb pdb:3NZW|rcsb pdb:3NZX|rcsb pdb:3OEU|rcsb pdb:3OEV|rcsb pdb:3OKJ|rcsb pdb:3SDI|rcsb pdb:3SDK|rcsb pdb:3SHJ|rcsb pdb:3TDD|rcsb pdb:3UN4|rcsb pdb:3UN8|rcsb pdb:3WXR|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:4EU2|rcsb pdb:4FZC|rcsb pdb:4FZG|rcsb pdb:4G4S|rcsb pdb:4GK7|rcsb pdb:4HNP|rcsb pdb:4HRC|rcsb pdb:4HRD|rcsb pdb:4INR|rcsb pdb:4INT|rcsb pdb:4INU|rcsb pdb:4J70|rcsb pdb:4JSQ|rcsb pdb:4JSU|rcsb pdb:4JT0|rcsb pdb:4LQI|rcsb pdb:4LTC|rcsb pdb:4NNN|rcsb pdb:4NNW|rcsb pdb:4NO1|rcsb pdb:4NO6|rcsb pdb:4NO8|rcsb pdb:4NO9|rcsb pdb:5FGE|rcsb pdb:5FGF|rcsb pdb:5FGG|rcsb pdb:5FGH|rcsb pdb:5FGI|rcsb pdb:5FHS|rcsb pdb:5JHR|rcsb pdb:5JHS|rcsb pdb:5L52|rcsb pdb:5L54|rcsb pdb:5L55|rcsb pdb:5L5A|rcsb pdb:5L5B|rcsb pdb:5L5D|rcsb pdb:5L5E|rcsb pdb:5L5F|rcsb pdb:5L5H|rcsb pdb:5L5I|rcsb pdb:5L5J|rcsb pdb:5L5O|rcsb pdb:5L5P|rcsb pdb:5L5Q|rcsb pdb:5L5R|rcsb pdb:4Q1S|rcsb pdb:4QBY|rcsb pdb:4QLQ|rcsb pdb:4QLS|rcsb pdb:4QLT|rcsb pdb:4QLU|rcsb pdb:4QLV|rcsb pdb:4QUX|rcsb pdb:4QUY|rcsb pdb:4QV0|rcsb pdb:4QV1|rcsb pdb:4QV3|rcsb pdb:4QV4|rcsb pdb:4QV5|rcsb pdb:4QV6|rcsb pdb:4QV7|rcsb pdb:4QV8|rcsb pdb:4QV9|rcsb pdb:4QVL|ensemblfungi:YMR314W(gene)|ensemblfungi:YMR314W_mRNA(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0042175"(nuclear outer membrane-endoplasmic reticulum membrane network)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR035144|rcsb pdb:1FNT|rcsb pdb:1G0U|rcsb pdb:1G65|rcsb pdb:1JD2|rcsb pdb:1RYP|rcsb pdb:1Z7Q|rcsb pdb:2F16|rcsb pdb:2FAK|rcsb pdb:2GPL|rcsb pdb:2ZCY|rcsb pdb:3BDM|rcsb pdb:3D29|rcsb pdb:3DY3|rcsb pdb:3DY4|rcsb pdb:3E47|rcsb pdb:3GPJ|rcsb pdb:3GPT|rcsb pdb:3GPW|rcsb pdb:4QVM|rcsb pdb:4QVN|rcsb pdb:4QVP|rcsb pdb:4QVQ|rcsb pdb:4QVV|rcsb pdb:4QVW|rcsb pdb:4QVY|rcsb pdb:4QW0|rcsb pdb:4QW1|rcsb pdb:4QW3|rcsb pdb:4QW4|rcsb pdb:4QW5|rcsb pdb:4QW6|rcsb pdb:4QW7|rcsb pdb:4QWF|rcsb pdb:4QWG|rcsb pdb:4QWI|rcsb pdb:4QWJ|rcsb pdb:4QWK|rcsb pdb:4QWL|rcsb pdb:4QWR|rcsb pdb:4QWS|rcsb pdb:4QWU|rcsb pdb:4QWX|rcsb pdb:4QXJ|rcsb pdb:4QZ0|rcsb pdb:4QZ1|rcsb pdb:4QZ2|rcsb pdb:4QZ3|rcsb pdb:4QZ4|rcsb pdb:4QZ5|rcsb pdb:4QZ6|rcsb pdb:4QZ7|rcsb pdb:4QZW|rcsb pdb:4QZX|rcsb pdb:4QZZ|rcsb pdb:4R00|rcsb pdb:4R02|rcsb pdb:4R17|rcsb pdb:4R18|rcsb pdb:4RUR|rcsb pdb:4V7O|rcsb pdb:4X6Z|rcsb pdb:4Y69|rcsb pdb:4Y6A|rcsb pdb:4Y6V|rcsb pdb:4Y6Z|rcsb pdb:4Y70|rcsb pdb:4Y74|rcsb pdb:4Y75|rcsb pdb:4Y77|rcsb pdb:4Y78|rcsb pdb:4Y7W|rcsb pdb:5LTT|rcsb pdb:5M2B|rcsb pdb:5MP9|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5NIF|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6G7F|rcsb pdb:6G8M|rcsb pdb:6G8N|rcsb pdb:6GOP|rcsb pdb:6H39|rcsb pdb:6HTB|rcsb pdb:6HTC|rcsb pdb:6HTD|rcsb pdb:6HTP|rcsb pdb:6HTR|rcsb pdb:6HUB|rcsb pdb:6HUC|rcsb pdb:6HUQ|rcsb pdb:6HUU|rcsb pdb:6HUV|rcsb pdb:6HV3|rcsb pdb:6HV4|rcsb pdb:6HV5|rcsb pdb:6HV7|rcsb pdb:6HVA|rcsb pdb:6HVR|rcsb pdb:6HVS|rcsb pdb:6HVT|rcsb pdb:6HVU|rcsb pdb:6HVV|rcsb pdb:5L5S|rcsb pdb:5L5T|rcsb pdb:5L5U|rcsb pdb:5L5V|rcsb pdb:5L5W|rcsb pdb:5L5X|rcsb pdb:5L5Y|rcsb pdb:5L5Z|rcsb pdb:5L60|rcsb pdb:5L61|rcsb pdb:5L62|rcsb pdb:5L63|rcsb pdb:5L64|rcsb pdb:5L65|rcsb pdb:5L66|rcsb pdb:5L67|rcsb pdb:5L68|rcsb pdb:5L69|rcsb pdb:5L6A|rcsb pdb:5L6B|rcsb pdb:5L6C|rcsb pdb:5LAI|rcsb pdb:5LAJ|rcsb pdb:6HVW|rcsb pdb:6HVX|rcsb pdb:6HVY|rcsb pdb:6HW0|rcsb pdb:6HW3|rcsb pdb:6HW4|rcsb pdb:6HW5|rcsb pdb:6HW6|rcsb pdb:6HW7|rcsb pdb:6HW8|rcsb pdb:6HW9|rcsb pdb:6HWA|rcsb pdb:6HWB|rcsb pdb:6HWC|rcsb pdb:6HWD|rcsb pdb:6HWE|rcsb pdb:6HWF|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2X|rcsb pdb:6J30|rcsb pdb:6ZOU|rcsb pdb:6ZP6|rcsb pdb:6ZP8|rcsb pdb:7LS5|rcsb pdb:7LS6|rcsb pdb:7LSX|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|rcsb pdb:6J2Q|refseq:NP_014045.1|sgd:S000004931|mint:P40302|dip:DIP-1528N	-	-	crc64:C43CBCC1C6B9E39E	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2018/04/06	rogid:jcCTXDx1bJq3K5mgNUD73jeWeBU9606	rogid:C9GPb0JAklkBz0t/YYqRMNEiQss559292	intact-crc:2CB02136C7E20129|rigid:cavY4vnk2ijUHCXNWZ63l8OL7sk	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P40454	uniprotkb:Q96CV9-2	intact:EBI-25278|uniprotkb:D6VVD4|ensemblfungi:YIL153W	intact:EBI-9091423|ensembl:ENSP00000368027|ensembl:ENSP00000368040	psi-mi:ptpa1_yeast(display_long)|uniprotkb:YIL153W(locus name)|uniprotkb:RRD1(gene name)|psi-mi:RRD1(display_short)|uniprotkb:NCS1(gene name synonym)|uniprotkb:YPA1(gene name synonym)|uniprotkb:Peptidyl-prolyl cis-trans isomerase PTPA-1(gene name synonym)|uniprotkb:Phosphotyrosyl phosphatase activator 1(gene name synonym)	psi-mi:q96cv9-2(display_long)|uniprotkb:E3-14.7K-interacting protein(gene name synonym)|uniprotkb:FIP-2(gene name synonym)|uniprotkb:FIP2(gene name synonym)|uniprotkb:GLC1E(gene name synonym)|uniprotkb:HIP7(gene name synonym)|uniprotkb:HYPL(gene name synonym)|uniprotkb:Huntingtin yeast partner L(gene name synonym)|uniprotkb:Huntingtin-interacting protein 7(gene name synonym)|uniprotkb:Huntingtin-interacting protein L(gene name synonym)|uniprotkb:NEMO-related protein(gene name synonym)|uniprotkb:NRP(gene name synonym)|uniprotkb:Optic neuropathy-inducing protein(gene name synonym)|uniprotkb:Transcription factor IIIA-interacting protein(gene name synonym)|uniprotkb:OPTN(gene name)|psi-mi:OPTN(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553540|imex:IM-24995-3956	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012113.1|sgd:S000001415|mint:P40454|dip:DIP-5663N|ensemblfungi:YIL153W(gene)|ensemblfungi:YIL153W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006914"(autophagy)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008160"(protein tyrosine phosphatase activator activity)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0043618"(regulation of transcription from RNA polymerase II promoter in response to stress)|interpro:IPR004327(Phosphotyrosyl phosphatase activator, PTPA)|interpro:IPR037218|interpro:IPR043170|rcsb pdb:2IXO|rcsb pdb:2IXP	intact:EBI-748974(isoform-parent)|ensembl:ENST00000378752(transcript)|ensembl:ENST00000378764(transcript)|ensembl:ENSG00000123240(gene)|uniprotkb:Q96CV9-2(isoform-parent)	-	-	isoform-comment:No experimental confirmation available.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2018/04/06	rogid:It2q8WlpmvLEZ1fqpRF5Fypw9Q4559292	rogid:ygzEQkiDJwDAMUuFQuOWsSIqwAk9606	intact-crc:612F440C48737DCD|rigid:Bmag+6huo34L9cXAp9+ovi4Xffs	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96CV9	uniprotkb:P01123	intact:EBI-748974|uniprotkb:Q5T672|uniprotkb:Q5T673|uniprotkb:Q5T674|uniprotkb:Q5T675|uniprotkb:Q7LDL9|uniprotkb:Q8N562|uniprotkb:Q9UET9|uniprotkb:Q9UEV4|uniprotkb:Q9Y218|uniprotkb:B3KP00|uniprotkb:D3DRS4|uniprotkb:D3DRS8|ensembl:ENSP00000263036|ensembl:ENSP00000368021|ensembl:ENSP00000368022|ensembl:ENSP00000368032	intact:EBI-29496|uniprotkb:D6VTJ2|ensemblfungi:YFL038C	psi-mi:optn_human(display_long)|uniprotkb:HYPL(gene name synonym)|uniprotkb:Optic neuropathy-inducing protein(gene name synonym)|uniprotkb:E3-14.7K-interacting protein(gene name synonym)|uniprotkb:FIP-2(gene name synonym)|uniprotkb:Huntingtin-interacting protein L(gene name synonym)|uniprotkb:Huntingtin yeast partner L(gene name synonym)|uniprotkb:NEMO-related protein(gene name synonym)|uniprotkb:Transcription factor IIIA-interacting protein(gene name synonym)|uniprotkb:OPTN(gene name)|psi-mi:OPTN(display_short)|uniprotkb:FIP2(gene name synonym)|uniprotkb:GLC1E(gene name synonym)|uniprotkb:NRP(gene name synonym)|uniprotkb:HIP7(gene name synonym)|uniprotkb:Huntingtin-interacting protein 7(gene name synonym)	psi-mi:ypt1_yeast(display_long)|uniprotkb:YFL038C(locus name)|uniprotkb:YPT1(gene name)|psi-mi:YPT1(display_short)|uniprotkb:YP2(gene name synonym)|uniprotkb:Rab GTPase YPT1(gene name synonym)|uniprotkb:Transport GTPase YPT1(gene name synonym)|uniprotkb:Protein YP2(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553528|imex:IM-24995-3953	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001008212.1|refseq:NP_001008213.1|refseq:NP_001008214.1|refseq:NP_068815.2|ensembl:ENSG00000123240(gene)|ensembl:ENST00000263036(transcript)|ensembl:ENST00000378747(transcript)|ensembl:ENST00000378748(transcript)|ensembl:ENST00000378757(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001920"(negative regulation of receptor recycling)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0007030"(Golgi organization)|go:"GO:0007165"(signal transduction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008219"(cell death)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0061734"(parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:1904417"(positive regulation of xenophagy)|interpro:IPR021063|interpro:IPR032419|interpro:IPR032939|interpro:IPR034735|mint:Q96CV9|rcsb pdb:2LO4|rcsb pdb:2LUE|rcsb pdb:3VTV|rcsb pdb:3VTW|rcsb pdb:5AAZ|rcsb pdb:5B83|rcsb pdb:5EOA|rcsb pdb:5EOF|rcsb pdb:7CZM|reactome:R-HSA-2565942|reactome:R-HSA-8854214|dip:DIP-42001N	refseq:NP_116615.1|sgd:S000001856|dip:DIP-2019N|mint:P01123|ensemblfungi:YFL038C(gene)|ensemblfungi:YFL038C_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005795"(Golgi stack)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0012505"(endomembrane system)|go:"GO:0016236"(macroautophagy)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0032456"(endocytic recycling)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0034498"(early endosome to Golgi transport)|go:"GO:0035493"(SNARE complex assembly)|go:"GO:0035494"(SNARE complex disassembly)|go:"GO:0043549"(regulation of kinase activity)|go:"GO:0048194"(Golgi vesicle budding)|go:"GO:0048211"(Golgi vesicle docking)|go:"GO:0061709"(reticulophagy)|go:"GO:0090114"(COPII-coated vesicle budding)|go:"GO:1900101"(regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1990261"(pre-mRNA catabolic process)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|rcsb pdb:1UKV|rcsb pdb:1YZN|rcsb pdb:2BCG|rcsb pdb:3CUE|rcsb pdb:7KMT|reactome:R-SCE-162658|reactome:R-SCE-204005|reactome:R-SCE-6807878|reactome:R-SCE-6811434|reactome:R-SCE-8873719|reactome:R-SCE-8876198	-	-	crc64:F8C704F6BF2D227B	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2018/04/06	rogid:jcCTXDx1bJq3K5mgNUD73jeWeBU9606	rogid:IMz/iERXs1zvX+wgJ9x7Uk0ovQ8559292	intact-crc:E1AD0C5AEF6ECBF8|rigid:XU2Ln8eZWI9Gyv83WsGcWnDzStU	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P40454	uniprotkb:Q96CV9	intact:EBI-25278|uniprotkb:D6VVD4|ensemblfungi:YIL153W	intact:EBI-748974|uniprotkb:Q5T672|uniprotkb:Q5T673|uniprotkb:Q5T674|uniprotkb:Q5T675|uniprotkb:Q7LDL9|uniprotkb:Q8N562|uniprotkb:Q9UET9|uniprotkb:Q9UEV4|uniprotkb:Q9Y218|uniprotkb:B3KP00|uniprotkb:D3DRS4|uniprotkb:D3DRS8|ensembl:ENSP00000263036|ensembl:ENSP00000368021|ensembl:ENSP00000368022|ensembl:ENSP00000368032	psi-mi:ptpa1_yeast(display_long)|uniprotkb:YIL153W(locus name)|uniprotkb:RRD1(gene name)|psi-mi:RRD1(display_short)|uniprotkb:NCS1(gene name synonym)|uniprotkb:YPA1(gene name synonym)|uniprotkb:Peptidyl-prolyl cis-trans isomerase PTPA-1(gene name synonym)|uniprotkb:Phosphotyrosyl phosphatase activator 1(gene name synonym)	psi-mi:optn_human(display_long)|uniprotkb:HYPL(gene name synonym)|uniprotkb:Optic neuropathy-inducing protein(gene name synonym)|uniprotkb:E3-14.7K-interacting protein(gene name synonym)|uniprotkb:FIP-2(gene name synonym)|uniprotkb:Huntingtin-interacting protein L(gene name synonym)|uniprotkb:Huntingtin yeast partner L(gene name synonym)|uniprotkb:NEMO-related protein(gene name synonym)|uniprotkb:Transcription factor IIIA-interacting protein(gene name synonym)|uniprotkb:OPTN(gene name)|psi-mi:OPTN(display_short)|uniprotkb:FIP2(gene name synonym)|uniprotkb:GLC1E(gene name synonym)|uniprotkb:NRP(gene name synonym)|uniprotkb:HIP7(gene name synonym)|uniprotkb:Huntingtin-interacting protein 7(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553532|imex:IM-24995-3954	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012113.1|sgd:S000001415|mint:P40454|dip:DIP-5663N|ensemblfungi:YIL153W(gene)|ensemblfungi:YIL153W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006914"(autophagy)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008160"(protein tyrosine phosphatase activator activity)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0043618"(regulation of transcription from RNA polymerase II promoter in response to stress)|interpro:IPR004327(Phosphotyrosyl phosphatase activator, PTPA)|interpro:IPR037218|interpro:IPR043170|rcsb pdb:2IXO|rcsb pdb:2IXP	refseq:NP_001008212.1|refseq:NP_001008213.1|refseq:NP_001008214.1|refseq:NP_068815.2|ensembl:ENSG00000123240(gene)|ensembl:ENST00000263036(transcript)|ensembl:ENST00000378747(transcript)|ensembl:ENST00000378748(transcript)|ensembl:ENST00000378757(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001920"(negative regulation of receptor recycling)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0007030"(Golgi organization)|go:"GO:0007165"(signal transduction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008219"(cell death)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0061734"(parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:1904417"(positive regulation of xenophagy)|interpro:IPR021063|interpro:IPR032419|interpro:IPR032939|interpro:IPR034735|mint:Q96CV9|rcsb pdb:2LO4|rcsb pdb:2LUE|rcsb pdb:3VTV|rcsb pdb:3VTW|rcsb pdb:5AAZ|rcsb pdb:5B83|rcsb pdb:5EOA|rcsb pdb:5EOF|rcsb pdb:7CZM|reactome:R-HSA-2565942|reactome:R-HSA-8854214|dip:DIP-42001N	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2018/04/06	rogid:It2q8WlpmvLEZ1fqpRF5Fypw9Q4559292	rogid:jcCTXDx1bJq3K5mgNUD73jeWeBU9606	intact-crc:AC96DC00300FDDE5|rigid:qhPMcGgyIW6NDLjpoigBcTOf55k	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q12329	uniprotkb:Q96D09	intact:EBI-8571|uniprotkb:D6VSF3|ensemblfungi:YDR171W	intact:EBI-473189|ensembl:ENSP00000339057|ensembl:ENSP00000437394|ensembl:ENSP00000437872|ensembl:ENSP00000507692|ensembl:ENSP00000508139|uniprotkb:Q8NAB4|uniprotkb:D3DXA0	psi-mi:hsp42_yeast(display_long)|uniprotkb:HSP42(gene name)|psi-mi:HSP42(display_short)|uniprotkb:YDR171W(locus name)|uniprotkb:YD9395.04(orf name)|uniprotkb:42 kDa heat shock protein(gene name synonym)	psi-mi:gasp2_human(display_long)|uniprotkb:GPRASP2(gene name)|psi-mi:GPRASP2(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553564|imex:IM-24995-3962	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010456.1|sgd:S000002578|mint:Q12329|dip:DIP-2515N|ensemblfungi:YDR171W(gene)|ensemblfungi:YDR171W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0009408"(response to heat)|go:"GO:0009651"(response to salt stress)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043621"(protein self-association)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0140311"(protein sequestering activity)|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR031107	ensembl:ENSG00000158301(gene)|ensembl:ENST00000332262(transcript)|ensembl:ENST00000483720(transcript)|ensembl:ENST00000486814(transcript)|ensembl:ENST00000535209(transcript)|ensembl:ENST00000543253(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0061484"(hematopoietic stem cell homeostasis)|interpro:IPR006911(Protein of unknown function DUF634)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR043374|refseq:NP_001004051.1|refseq:NP_001171803.1|refseq:NP_001171804.1|refseq:NP_001171805.1|refseq:NP_001186747.1|refseq:NP_612446.1	-	crc64:DF353A76493E3CE6	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:izvrv04fA3zcBqTeUeHD/erKGf4559292	rogid:aUbvpCvGto1y4Rqnri7qaKaygQ89606	intact-crc:EC666A4B682B2623|rigid:BCJ58eKd4YPAhwvLi21UIAYmB3k	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P22217	uniprotkb:Q96D03	intact:EBI-19607|uniprotkb:D6VY45|ensemblfungi:YLR043C	intact:EBI-742054|uniprotkb:B2R7C3|ensembl:ENSP00000354830	psi-mi:trx1_yeast(display_long)|uniprotkb:TRX1(gene name)|psi-mi:TRX1(display_short)|uniprotkb:TRX2(gene name synonym)|uniprotkb:YLR043C(locus name)|uniprotkb:Thioredoxin I(gene name synonym)|uniprotkb:Thioredoxin-2(gene name synonym)	psi-mi:ddt4l_human(display_long)|uniprotkb:Protein regulated in development and DNA damage response 2(gene name synonym)|uniprotkb:HIF-1 responsive protein RTP801-like(gene name synonym)|uniprotkb:DDIT4L(gene name)|psi-mi:DDIT4L(display_short)|uniprotkb:REDD2(gene name synonym)|uniprotkb:RTP801L(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553560|imex:IM-24995-3961	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013144.1|sgd:S000004033|interpro:IPR005746(Thioredoxin)|interpro:IPR017937|interpro:IPR013766(Thioredoxin domain)|ensemblfungi:YLR043C(gene)|ensemblfungi:YLR043C_mRNA(transcript)|go:"GO:0000011"(vacuole inheritance)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0009263"(deoxyribonucleotide biosynthetic process)|go:"GO:0015031"(protein transport)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0015036"(disulfide oxidoreductase activity)|go:"GO:0042144"(vacuole fusion, non-autophagic)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0080058"(protein deglutathionylation)|rcsb pdb:2I9H|rcsb pdb:2N5A|rcsb pdb:2N5B|rcsb pdb:3F3Q|rcsb pdb:3F3R|go:"GO:0006662"(glycerol ether metabolic process)|mint:P22217|interpro:IPR036249	refseq:NP_660287.1|ensembl:ENSG00000145358(gene)|ensembl:ENST00000273990(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0009968"(negative regulation of signal transduction)|interpro:IPR012918(RTP801, C-terminal)|interpro:IPR038281	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:HTTjl3NGIuQllhjAI5NASyqqIlc559292	rogid:DHXiWraTchl3LZgh/lXlUr3LKwE9606	intact-crc:29C26154E2702A3A|rigid:Yyhl69PcyPOAWqvyRxqGPz4VrB8	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P40302	uniprotkb:Q96CV9-2	intact:EBI-13955|ensemblfungi:YMR314W|uniprotkb:D6W0E1	intact:EBI-9091423|ensembl:ENSP00000368027|ensembl:ENSP00000368040	psi-mi:psa6_yeast(display_long)|uniprotkb:PRE5(gene name)|psi-mi:PRE5(display_short)|uniprotkb:YMR314W(locus name)|uniprotkb:YM9924.06(orf name)|uniprotkb:Proteasome component PRE5(gene name synonym)|uniprotkb:Macropain subunit PRE5(gene name synonym)|uniprotkb:Proteinase YSCE subunit PRE5(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit PRE5(gene name synonym)	psi-mi:q96cv9-2(display_long)|uniprotkb:E3-14.7K-interacting protein(gene name synonym)|uniprotkb:FIP-2(gene name synonym)|uniprotkb:FIP2(gene name synonym)|uniprotkb:GLC1E(gene name synonym)|uniprotkb:HIP7(gene name synonym)|uniprotkb:HYPL(gene name synonym)|uniprotkb:Huntingtin yeast partner L(gene name synonym)|uniprotkb:Huntingtin-interacting protein 7(gene name synonym)|uniprotkb:Huntingtin-interacting protein L(gene name synonym)|uniprotkb:NEMO-related protein(gene name synonym)|uniprotkb:NRP(gene name synonym)|uniprotkb:Optic neuropathy-inducing protein(gene name synonym)|uniprotkb:Transcription factor IIIA-interacting protein(gene name synonym)|uniprotkb:OPTN(gene name)|psi-mi:OPTN(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553544|imex:IM-24995-3957	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:4Y8T|rcsb pdb:4Y8U|rcsb pdb:4Y9Y|rcsb pdb:4Y9Z|rcsb pdb:4YA0|rcsb pdb:4YA1|rcsb pdb:4YA2|rcsb pdb:4YA3|rcsb pdb:4YA4|rcsb pdb:4YA5|rcsb pdb:4Y7X|rcsb pdb:4Y7Y|rcsb pdb:4Y80|rcsb pdb:4Y81|rcsb pdb:4Y82|rcsb pdb:4Y84|rcsb pdb:4Y8G|rcsb pdb:4Y8H|rcsb pdb:4Y8I|rcsb pdb:4Y8J|rcsb pdb:4Y8K|rcsb pdb:4Y8L|rcsb pdb:4Y8M|rcsb pdb:4Y8N|rcsb pdb:4Y8O|rcsb pdb:4Y8P|rcsb pdb:4Y8Q|rcsb pdb:4Y8R|rcsb pdb:4Y8S|rcsb pdb:5FG7|rcsb pdb:5FG9|rcsb pdb:5FGA|rcsb pdb:4YA7|rcsb pdb:4YA9|rcsb pdb:4Z1L|rcsb pdb:5A5B|rcsb pdb:5AHJ|rcsb pdb:5BOU|rcsb pdb:5BXL|rcsb pdb:5BXN|rcsb pdb:5CGF|rcsb pdb:5CGG|rcsb pdb:5CGH|rcsb pdb:5CGI|rcsb pdb:5CZ4|rcsb pdb:5CZ5|rcsb pdb:5CZ6|rcsb pdb:5CZ7|rcsb pdb:5CZ8|rcsb pdb:5CZ9|rcsb pdb:5CZA|rcsb pdb:5D0S|rcsb pdb:5D0T|rcsb pdb:5D0V|rcsb pdb:5D0W|rcsb pdb:5D0X|rcsb pdb:5D0Z|rcsb pdb:5DKI|rcsb pdb:5DKJ|rcsb pdb:5FGD|rcsb pdb:3HYE|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:3MG0|rcsb pdb:3MG4|rcsb pdb:3MG6|rcsb pdb:3MG7|rcsb pdb:3MG8|rcsb pdb:3NZJ|rcsb pdb:3NZW|rcsb pdb:3NZX|rcsb pdb:3OEU|rcsb pdb:3OEV|rcsb pdb:3OKJ|rcsb pdb:3SDI|rcsb pdb:3SDK|rcsb pdb:3SHJ|rcsb pdb:3TDD|rcsb pdb:3UN4|rcsb pdb:3UN8|rcsb pdb:3WXR|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:4EU2|rcsb pdb:4FZC|rcsb pdb:4FZG|rcsb pdb:4G4S|rcsb pdb:4GK7|rcsb pdb:4HNP|rcsb pdb:4HRC|rcsb pdb:4HRD|rcsb pdb:4INR|rcsb pdb:4INT|rcsb pdb:4INU|rcsb pdb:4J70|rcsb pdb:4JSQ|rcsb pdb:4JSU|rcsb pdb:4JT0|rcsb pdb:4LQI|rcsb pdb:4LTC|rcsb pdb:4NNN|rcsb pdb:4NNW|rcsb pdb:4NO1|rcsb pdb:4NO6|rcsb pdb:4NO8|rcsb pdb:4NO9|rcsb pdb:5FGE|rcsb pdb:5FGF|rcsb pdb:5FGG|rcsb pdb:5FGH|rcsb pdb:5FGI|rcsb pdb:5FHS|rcsb pdb:5JHR|rcsb pdb:5JHS|rcsb pdb:5L52|rcsb pdb:5L54|rcsb pdb:5L55|rcsb pdb:5L5A|rcsb pdb:5L5B|rcsb pdb:5L5D|rcsb pdb:5L5E|rcsb pdb:5L5F|rcsb pdb:5L5H|rcsb pdb:5L5I|rcsb pdb:5L5J|rcsb pdb:5L5O|rcsb pdb:5L5P|rcsb pdb:5L5Q|rcsb pdb:5L5R|rcsb pdb:4Q1S|rcsb pdb:4QBY|rcsb pdb:4QLQ|rcsb pdb:4QLS|rcsb pdb:4QLT|rcsb pdb:4QLU|rcsb pdb:4QLV|rcsb pdb:4QUX|rcsb pdb:4QUY|rcsb pdb:4QV0|rcsb pdb:4QV1|rcsb pdb:4QV3|rcsb pdb:4QV4|rcsb pdb:4QV5|rcsb pdb:4QV6|rcsb pdb:4QV7|rcsb pdb:4QV8|rcsb pdb:4QV9|rcsb pdb:4QVL|ensemblfungi:YMR314W(gene)|ensemblfungi:YMR314W_mRNA(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0042175"(nuclear outer membrane-endoplasmic reticulum membrane network)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR035144|rcsb pdb:1FNT|rcsb pdb:1G0U|rcsb pdb:1G65|rcsb pdb:1JD2|rcsb pdb:1RYP|rcsb pdb:1Z7Q|rcsb pdb:2F16|rcsb pdb:2FAK|rcsb pdb:2GPL|rcsb pdb:2ZCY|rcsb pdb:3BDM|rcsb pdb:3D29|rcsb pdb:3DY3|rcsb pdb:3DY4|rcsb pdb:3E47|rcsb pdb:3GPJ|rcsb pdb:3GPT|rcsb pdb:3GPW|rcsb pdb:4QVM|rcsb pdb:4QVN|rcsb pdb:4QVP|rcsb pdb:4QVQ|rcsb pdb:4QVV|rcsb pdb:4QVW|rcsb pdb:4QVY|rcsb pdb:4QW0|rcsb pdb:4QW1|rcsb pdb:4QW3|rcsb pdb:4QW4|rcsb pdb:4QW5|rcsb pdb:4QW6|rcsb pdb:4QW7|rcsb pdb:4QWF|rcsb pdb:4QWG|rcsb pdb:4QWI|rcsb pdb:4QWJ|rcsb pdb:4QWK|rcsb pdb:4QWL|rcsb pdb:4QWR|rcsb pdb:4QWS|rcsb pdb:4QWU|rcsb pdb:4QWX|rcsb pdb:4QXJ|rcsb pdb:4QZ0|rcsb pdb:4QZ1|rcsb pdb:4QZ2|rcsb pdb:4QZ3|rcsb pdb:4QZ4|rcsb pdb:4QZ5|rcsb pdb:4QZ6|rcsb pdb:4QZ7|rcsb pdb:4QZW|rcsb pdb:4QZX|rcsb pdb:4QZZ|rcsb pdb:4R00|rcsb pdb:4R02|rcsb pdb:4R17|rcsb pdb:4R18|rcsb pdb:4RUR|rcsb pdb:4V7O|rcsb pdb:4X6Z|rcsb pdb:4Y69|rcsb pdb:4Y6A|rcsb pdb:4Y6V|rcsb pdb:4Y6Z|rcsb pdb:4Y70|rcsb pdb:4Y74|rcsb pdb:4Y75|rcsb pdb:4Y77|rcsb pdb:4Y78|rcsb pdb:4Y7W|rcsb pdb:5LTT|rcsb pdb:5M2B|rcsb pdb:5MP9|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5NIF|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6G7F|rcsb pdb:6G8M|rcsb pdb:6G8N|rcsb pdb:6GOP|rcsb pdb:6H39|rcsb pdb:6HTB|rcsb pdb:6HTC|rcsb pdb:6HTD|rcsb pdb:6HTP|rcsb pdb:6HTR|rcsb pdb:6HUB|rcsb pdb:6HUC|rcsb pdb:6HUQ|rcsb pdb:6HUU|rcsb pdb:6HUV|rcsb pdb:6HV3|rcsb pdb:6HV4|rcsb pdb:6HV5|rcsb pdb:6HV7|rcsb pdb:6HVA|rcsb pdb:6HVR|rcsb pdb:6HVS|rcsb pdb:6HVT|rcsb pdb:6HVU|rcsb pdb:6HVV|rcsb pdb:5L5S|rcsb pdb:5L5T|rcsb pdb:5L5U|rcsb pdb:5L5V|rcsb pdb:5L5W|rcsb pdb:5L5X|rcsb pdb:5L5Y|rcsb pdb:5L5Z|rcsb pdb:5L60|rcsb pdb:5L61|rcsb pdb:5L62|rcsb pdb:5L63|rcsb pdb:5L64|rcsb pdb:5L65|rcsb pdb:5L66|rcsb pdb:5L67|rcsb pdb:5L68|rcsb pdb:5L69|rcsb pdb:5L6A|rcsb pdb:5L6B|rcsb pdb:5L6C|rcsb pdb:5LAI|rcsb pdb:5LAJ|rcsb pdb:6HVW|rcsb pdb:6HVX|rcsb pdb:6HVY|rcsb pdb:6HW0|rcsb pdb:6HW3|rcsb pdb:6HW4|rcsb pdb:6HW5|rcsb pdb:6HW6|rcsb pdb:6HW7|rcsb pdb:6HW8|rcsb pdb:6HW9|rcsb pdb:6HWA|rcsb pdb:6HWB|rcsb pdb:6HWC|rcsb pdb:6HWD|rcsb pdb:6HWE|rcsb pdb:6HWF|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2X|rcsb pdb:6J30|rcsb pdb:6ZOU|rcsb pdb:6ZP6|rcsb pdb:6ZP8|rcsb pdb:7LS5|rcsb pdb:7LS6|rcsb pdb:7LSX|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|rcsb pdb:6J2Q|refseq:NP_014045.1|sgd:S000004931|mint:P40302|dip:DIP-1528N	intact:EBI-748974(isoform-parent)|ensembl:ENST00000378752(transcript)|ensembl:ENST00000378764(transcript)|ensembl:ENSG00000123240(gene)|uniprotkb:Q96CV9-2(isoform-parent)	-	crc64:C43CBCC1C6B9E39E	isoform-comment:No experimental confirmation available.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2018/04/06	rogid:C9GPb0JAklkBz0t/YYqRMNEiQss559292	rogid:ygzEQkiDJwDAMUuFQuOWsSIqwAk9606	intact-crc:635C35FD101C1506|rigid:oIuyRqKqPpz576ZXWukSRwQC/v4	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P40325	uniprotkb:Q96CV9-2	intact:EBI-23614|uniprotkb:D6VV46|ensemblfungi:YGR268C	intact:EBI-9091423|ensembl:ENSP00000368027|ensembl:ENSP00000368040	psi-mi:hua1_yeast(display_long)|uniprotkb:HUA1(gene name)|psi-mi:HUA1(display_short)|uniprotkb:YGR268C(locus name)	psi-mi:q96cv9-2(display_long)|uniprotkb:E3-14.7K-interacting protein(gene name synonym)|uniprotkb:FIP-2(gene name synonym)|uniprotkb:FIP2(gene name synonym)|uniprotkb:GLC1E(gene name synonym)|uniprotkb:HIP7(gene name synonym)|uniprotkb:HYPL(gene name synonym)|uniprotkb:Huntingtin yeast partner L(gene name synonym)|uniprotkb:Huntingtin-interacting protein 7(gene name synonym)|uniprotkb:Huntingtin-interacting protein L(gene name synonym)|uniprotkb:NEMO-related protein(gene name synonym)|uniprotkb:NRP(gene name synonym)|uniprotkb:Optic neuropathy-inducing protein(gene name synonym)|uniprotkb:Transcription factor IIIA-interacting protein(gene name synonym)|uniprotkb:OPTN(gene name)|psi-mi:OPTN(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553552|imex:IM-24995-3959	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003500|refseq:NP_011784.3|dip:DIP-1987N|ensemblfungi:YGR268C(gene)|ensemblfungi:YGR268C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|interpro:IPR038910	intact:EBI-748974(isoform-parent)|ensembl:ENST00000378752(transcript)|ensembl:ENST00000378764(transcript)|ensembl:ENSG00000123240(gene)|uniprotkb:Q96CV9-2(isoform-parent)	-	crc64:78029FD484168793	isoform-comment:No experimental confirmation available.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2018/04/06	rogid:xliNG9XUWbYRd0Nbu+xzCgxNrAs559292	rogid:ygzEQkiDJwDAMUuFQuOWsSIqwAk9606	intact-crc:CEC8C8952A0BC065|rigid:uOCMr9eJT/Mm90dBbTyVfrbsS5o	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P01123	uniprotkb:Q96CV9-2	intact:EBI-29496|uniprotkb:D6VTJ2|ensemblfungi:YFL038C	intact:EBI-9091423|ensembl:ENSP00000368027|ensembl:ENSP00000368040	psi-mi:ypt1_yeast(display_long)|uniprotkb:YFL038C(locus name)|uniprotkb:YPT1(gene name)|psi-mi:YPT1(display_short)|uniprotkb:YP2(gene name synonym)|uniprotkb:Rab GTPase YPT1(gene name synonym)|uniprotkb:Transport GTPase YPT1(gene name synonym)|uniprotkb:Protein YP2(gene name synonym)	psi-mi:q96cv9-2(display_long)|uniprotkb:E3-14.7K-interacting protein(gene name synonym)|uniprotkb:FIP-2(gene name synonym)|uniprotkb:FIP2(gene name synonym)|uniprotkb:GLC1E(gene name synonym)|uniprotkb:HIP7(gene name synonym)|uniprotkb:HYPL(gene name synonym)|uniprotkb:Huntingtin yeast partner L(gene name synonym)|uniprotkb:Huntingtin-interacting protein 7(gene name synonym)|uniprotkb:Huntingtin-interacting protein L(gene name synonym)|uniprotkb:NEMO-related protein(gene name synonym)|uniprotkb:NRP(gene name synonym)|uniprotkb:Optic neuropathy-inducing protein(gene name synonym)|uniprotkb:Transcription factor IIIA-interacting protein(gene name synonym)|uniprotkb:OPTN(gene name)|psi-mi:OPTN(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553548|imex:IM-24995-3958	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_116615.1|sgd:S000001856|dip:DIP-2019N|mint:P01123|ensemblfungi:YFL038C(gene)|ensemblfungi:YFL038C_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005795"(Golgi stack)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0012505"(endomembrane system)|go:"GO:0016236"(macroautophagy)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0032456"(endocytic recycling)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0034498"(early endosome to Golgi transport)|go:"GO:0035493"(SNARE complex assembly)|go:"GO:0035494"(SNARE complex disassembly)|go:"GO:0043549"(regulation of kinase activity)|go:"GO:0048194"(Golgi vesicle budding)|go:"GO:0048211"(Golgi vesicle docking)|go:"GO:0061709"(reticulophagy)|go:"GO:0090114"(COPII-coated vesicle budding)|go:"GO:1900101"(regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1990261"(pre-mRNA catabolic process)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|rcsb pdb:1UKV|rcsb pdb:1YZN|rcsb pdb:2BCG|rcsb pdb:3CUE|rcsb pdb:7KMT|reactome:R-SCE-162658|reactome:R-SCE-204005|reactome:R-SCE-6807878|reactome:R-SCE-6811434|reactome:R-SCE-8873719|reactome:R-SCE-8876198	intact:EBI-748974(isoform-parent)|ensembl:ENST00000378752(transcript)|ensembl:ENST00000378764(transcript)|ensembl:ENSG00000123240(gene)|uniprotkb:Q96CV9-2(isoform-parent)	-	crc64:F8C704F6BF2D227B	isoform-comment:No experimental confirmation available.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2018/04/06	rogid:IMz/iERXs1zvX+wgJ9x7Uk0ovQ8559292	rogid:ygzEQkiDJwDAMUuFQuOWsSIqwAk9606	intact-crc:B0D355A2BAF541AA|rigid:iKF4Z+I6+j8IuUp9FYB7VvlHFgw	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P22803	uniprotkb:Q96D03	intact:EBI-19598|uniprotkb:D6VUZ2|ensemblfungi:YGR209C	intact:EBI-742054|uniprotkb:B2R7C3|ensembl:ENSP00000354830	psi-mi:trx2_yeast(display_long)|uniprotkb:TRX2(gene name)|psi-mi:TRX2(display_short)|uniprotkb:TRX1(gene name synonym)|uniprotkb:G7746(orf name)|uniprotkb:YGR209C(locus name)|uniprotkb:Thioredoxin II(gene name synonym)|uniprotkb:Thioredoxin-1(gene name synonym)	psi-mi:ddt4l_human(display_long)|uniprotkb:Protein regulated in development and DNA damage response 2(gene name synonym)|uniprotkb:HIF-1 responsive protein RTP801-like(gene name synonym)|uniprotkb:DDIT4L(gene name)|psi-mi:DDIT4L(display_short)|uniprotkb:REDD2(gene name synonym)|uniprotkb:RTP801L(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553556|imex:IM-24995-3960	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003441|go:"GO:0009263"(deoxyribonucleotide biosynthetic process)|go:"GO:0015031"(protein transport)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0015036"(disulfide oxidoreductase activity)|go:"GO:0042144"(vacuole fusion, non-autophagic)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0080058"(protein deglutathionylation)|interpro:IPR005746(Thioredoxin)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017937|interpro:IPR036249|rcsb pdb:2FA4|rcsb pdb:2HSY|rcsb pdb:3PIN|rcsb pdb:4DSS|rcsb pdb:7BVV|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|ensemblfungi:YGR209C(gene)|ensemblfungi:YGR209C_mRNA(transcript)|go:"GO:0000011"(vacuole inheritance)|go:"GO:0000103"(sulfate assimilation)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006662"(glycerol ether metabolic process)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|refseq:NP_011725.3|dip:DIP-5552N|mint:P22803	refseq:NP_660287.1|ensembl:ENSG00000145358(gene)|ensembl:ENST00000273990(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0009968"(negative regulation of signal transduction)|interpro:IPR012918(RTP801, C-terminal)|interpro:IPR038281	-	crc64:071503762C90D451	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:pRt9fGROPXW+o4g6ynOmCDiclFk559292	rogid:DHXiWraTchl3LZgh/lXlUr3LKwE9606	intact-crc:466F78EF79BEFF07|rigid:8t0PJQHcNgIXZyZ5Zhffs+CPVkg	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96DZ9-2	uniprotkb:P32453	intact:EBI-11522780|ensembl:ENSP00000352270|ensembl:ENSP00000497215	intact:EBI-3306|uniprotkb:D6W0N0|ensemblfungi:YNL315C	psi-mi:q96dz9-2(display_long)|uniprotkb:CMTM5(gene name)|psi-mi:CMTM5(display_short)|uniprotkb:CKLFSF5(gene name synonym)|uniprotkb:Chemokine-like factor superfamily member 5(gene name synonym)	psi-mi:atp11_yeast(display_long)|uniprotkb:ATP11(gene name)|psi-mi:ATP11(display_short)|uniprotkb:N0357(orf name)|uniprotkb:YNL315C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553588|imex:IM-24995-3968	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000166091(gene)|ensembl:ENST00000359320(transcript)|ensembl:ENST00000649278(transcript)|intact:EBI-2548702(isoform-parent)|uniprotkb:Q96DZ9-2(isoform-parent)	refseq:NP_014084.1|sgd:S000005259|dip:DIP-3026N|mint:P32453|ensemblfungi:YNL315C(gene)|ensemblfungi:YNL315C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0033615"(mitochondrial proton-transporting ATP synthase complex assembly)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR010591(ATP11)	-	-	crc64:61109AA4D338F2CD	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:2TJ7rZKQNb5hH5gz9i+ujOEOIOg9606	rogid:JsQu6HtKtGqAVhHzaPVc8IMYdqM559292	intact-crc:42C9CCE112D4B301|rigid:bdERYZdEf3ixhCdnf5xhi5ZNSm0	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q05515	uniprotkb:Q96DZ9-2	intact:EBI-38400|uniprotkb:D6VSX6|ensemblfungi:YDR346C	intact:EBI-11522780|ensembl:ENSP00000352270|ensembl:ENSP00000497215	psi-mi:svf1_yeast(display_long)|uniprotkb:SVF1(gene name)|psi-mi:SVF1(display_short)|uniprotkb:SGI1(gene name synonym)|uniprotkb:YDR346C(locus name)	psi-mi:q96dz9-2(display_long)|uniprotkb:CMTM5(gene name)|psi-mi:CMTM5(display_short)|uniprotkb:CKLFSF5(gene name synonym)|uniprotkb:Chemokine-like factor superfamily member 5(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553584|imex:IM-24995-3967	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002754|refseq:NP_010633.3|mint:Q05515|dip:DIP-5243N|ensemblfungi:YDR346C(gene)|ensemblfungi:YDR346C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0034599"(cellular response to oxidative stress)|interpro:IPR013931(Oxidative stress survival, Svf1-like)|interpro:IPR033394	ensembl:ENSG00000166091(gene)|ensembl:ENST00000359320(transcript)|ensembl:ENST00000649278(transcript)|intact:EBI-2548702(isoform-parent)|uniprotkb:Q96DZ9-2(isoform-parent)	-	crc64:926A28FE140F87A5	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:K9DLW9y+JFX3NTUKWKHVb/YpPVg559292	rogid:2TJ7rZKQNb5hH5gz9i+ujOEOIOg9606	intact-crc:AD7290311A177DEF|rigid:cHfqz9yeOR0kWYXEyZ1Kfja6aYE	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P38340	uniprotkb:Q96DZ9-2	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-11522780|ensembl:ENSP00000352270|ensembl:ENSP00000497215	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:q96dz9-2(display_long)|uniprotkb:CMTM5(gene name)|psi-mi:CMTM5(display_short)|uniprotkb:CKLFSF5(gene name synonym)|uniprotkb:Chemokine-like factor superfamily member 5(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553568|imex:IM-24995-3963	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F	ensembl:ENSG00000166091(gene)|ensembl:ENST00000359320(transcript)|ensembl:ENST00000649278(transcript)|intact:EBI-2548702(isoform-parent)|uniprotkb:Q96DZ9-2(isoform-parent)	-	crc64:66699F37B0013088	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:2TJ7rZKQNb5hH5gz9i+ujOEOIOg9606	intact-crc:5DA8067A75D7841D|rigid:7Tza29kWNlcvzcQUi0MEeZ+mf3s	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96DZ9-2	uniprotkb:Q02724	intact:EBI-11522780|ensembl:ENSP00000352270|ensembl:ENSP00000497215	intact:EBI-20050|uniprotkb:D6W3Z2|ensemblfungi:YPL020C	psi-mi:q96dz9-2(display_long)|uniprotkb:CMTM5(gene name)|psi-mi:CMTM5(display_short)|uniprotkb:CKLFSF5(gene name synonym)|uniprotkb:Chemokine-like factor superfamily member 5(gene name synonym)	psi-mi:ulp1_yeast(display_long)|uniprotkb:ULP1(gene name)|psi-mi:ULP1(display_short)|uniprotkb:LPB11C(orf name)|uniprotkb:YPL020C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553576|imex:IM-24995-3965	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000166091(gene)|ensembl:ENST00000359320(transcript)|ensembl:ENST00000649278(transcript)|intact:EBI-2548702(isoform-parent)|uniprotkb:Q96DZ9-2(isoform-parent)	refseq:NP_015305.1|sgd:S000005941|ensemblfungi:YPL020C(gene)|ensemblfungi:YPL020C_mRNA(transcript)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005730"(nucleolus)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0016926"(protein desumoylation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070140"(SUMO-specific isopeptidase activity)|interpro:IPR003653(Peptidase C48, SUMO/Sentrin/Ubl1)|interpro:IPR038765|rcsb pdb:1EUV|rcsb pdb:2HKP|rcsb pdb:2HL8|rcsb pdb:2HL9|rcsb pdb:5H2V|rcsb pdb:5H2W|rcsb pdb:5H2X|reactome:R-SCE-3065679|reactome:R-SCE-6791226|dip:DIP-4041N|mint:Q02724	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:2TJ7rZKQNb5hH5gz9i+ujOEOIOg9606	rogid:H9B4qZf/ZMbHr7u4hbtR4fzz0ec559292	intact-crc:E4F3DB9FBD2EDF5B|rigid:bA9ChALF2ya3z9shfdEU0Vaxy9Q	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96DZ9-2	uniprotkb:Q07540	intact:EBI-11522780|ensembl:ENSP00000352270|ensembl:ENSP00000497215	intact:EBI-2206814|uniprotkb:D6VRN0|ensemblfungi:YDL120W	psi-mi:q96dz9-2(display_long)|uniprotkb:CMTM5(gene name)|psi-mi:CMTM5(display_short)|uniprotkb:CKLFSF5(gene name synonym)|uniprotkb:Chemokine-like factor superfamily member 5(gene name synonym)	psi-mi:frda_yeast(display_long)|uniprotkb:YFH1(gene name)|psi-mi:YFH1(display_short)|uniprotkb:YDL120W(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553572|imex:IM-24995-3964	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000166091(gene)|ensembl:ENST00000359320(transcript)|ensembl:ENST00000649278(transcript)|intact:EBI-2548702(isoform-parent)|uniprotkb:Q96DZ9-2(isoform-parent)	dip:DIP-7485N|refseq:NP_010163.1|sgd:S000002278|mint:Q07540|ensemblfungi:YDL120W(gene)|ensemblfungi:YDL120W_mRNA(transcript)|go:"GO:0004322"(ferroxidase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006121"(mitochondrial electron transport, succinate to ubiquinone)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0006783"(heme biosynthetic process)|go:"GO:0006811"(ion transport)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008199"(ferric iron binding)|go:"GO:0010040"("response to iron(II) ion")|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0018283"(iron incorporation into metallo-sulfur cluster)|go:"GO:0034986"(iron chaperone activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|interpro:IPR002908(Frataxin-like)|interpro:IPR017789(Frataxin)|interpro:IPR020895|interpro:IPR036524|rcsb pdb:2FQL|rcsb pdb:2GA5|rcsb pdb:3OEQ|rcsb pdb:3OER|rcsb pdb:4EC2|rcsb pdb:5T0V|rcsb pdb:5TRE|reactome:R-SCE-1268020|reactome:R-SCE-1362409|go:"GO:0008198"(ferrous iron binding)	-	-	crc64:AB1FF7478EF0E5D6	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:2TJ7rZKQNb5hH5gz9i+ujOEOIOg9606	rogid:4UcroTodEXb/5+xHGpnXDXf/rd8559292	intact-crc:E329965793CC0C88|rigid:TeTvZ46aWQK4pl4xiAKjWRnNeIU	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96DZ9-2	uniprotkb:P00431	intact:EBI-11522780|ensembl:ENSP00000352270|ensembl:ENSP00000497215	intact:EBI-4389|uniprotkb:Q6Q5M9|uniprotkb:D6VXC7|ensemblfungi:YKR066C	psi-mi:q96dz9-2(display_long)|uniprotkb:CMTM5(gene name)|psi-mi:CMTM5(display_short)|uniprotkb:CKLFSF5(gene name synonym)|uniprotkb:Chemokine-like factor superfamily member 5(gene name synonym)	psi-mi:ccpr_yeast(display_long)|uniprotkb:CCP1(gene name)|psi-mi:CCP1(display_short)|uniprotkb:CCP(gene name synonym)|uniprotkb:CPO(gene name synonym)|uniprotkb:YKR066C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553580|imex:IM-24995-3966	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000166091(gene)|ensembl:ENST00000359320(transcript)|ensembl:ENST00000649278(transcript)|intact:EBI-2548702(isoform-parent)|uniprotkb:Q96DZ9-2(isoform-parent)	refseq:NP_012992.1|sgd:S000001774|dip:DIP-6251N|ensemblfungi:YKR066C(gene)|ensemblfungi:YKR066C_mRNA(transcript)|go:"GO:0000302"(response to reactive oxygen species)|go:"GO:0004130"(cytochrome-c peroxidase activity)|go:"GO:0004601"(peroxidase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0020037"(heme binding)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0046872"(metal ion binding)|interpro:IPR002016(Haem peroxidase, plant/fungal/bacterial)|interpro:IPR002207(Plant ascorbate peroxidase)|interpro:IPR010255(Haem peroxidase)|interpro:IPR019793|interpro:IPR019794|interpro:IPR044831|rcsb pdb:1A2F|rcsb pdb:1A2G|rcsb pdb:1AA4|rcsb pdb:1AC4|rcsb pdb:1AC8|rcsb pdb:1AEB|rcsb pdb:1AED|rcsb pdb:1AEE|rcsb pdb:1AEF|rcsb pdb:1AEG|rcsb pdb:1AEH|rcsb pdb:1AEJ|rcsb pdb:1AEK|rcsb pdb:1AEM|rcsb pdb:1AEN|rcsb pdb:1AEO|rcsb pdb:1AEQ|rcsb pdb:1AES|rcsb pdb:1AET|rcsb pdb:1AEU|rcsb pdb:1AEV|rcsb pdb:1BEJ|rcsb pdb:1BEK|rcsb pdb:1BEM|rcsb pdb:1BEP|rcsb pdb:1BEQ|rcsb pdb:1BES|rcsb pdb:1BJ9|rcsb pdb:1BVA|rcsb pdb:1CCA|rcsb pdb:1CCB|rcsb pdb:1CCC|rcsb pdb:1CCE|rcsb pdb:1CCG|rcsb pdb:1CCI|rcsb pdb:1CCJ|rcsb pdb:1CCK|rcsb pdb:1CCL|rcsb pdb:1CCP|rcsb pdb:1CMP|rcsb pdb:1CMQ|rcsb pdb:1CMT|rcsb pdb:1CPD|rcsb pdb:1CPE|rcsb pdb:1CPF|rcsb pdb:1CPG|rcsb pdb:1CYF|rcsb pdb:1DCC|rcsb pdb:1DJ1|rcsb pdb:1DJ5|rcsb pdb:1DS4|rcsb pdb:1DSE|rcsb pdb:1DSG|rcsb pdb:1DSO|rcsb pdb:1DSP|rcsb pdb:1EBE|rcsb pdb:1JCI|rcsb pdb:1JDR|rcsb pdb:1KOK|rcsb pdb:1KRJ|rcsb pdb:1KXM|rcsb pdb:1KXN|rcsb pdb:1MK8|rcsb pdb:1MKQ|rcsb pdb:1MKR|rcsb pdb:1ML2|rcsb pdb:1RYC|rcsb pdb:1S6V|rcsb pdb:1S73|rcsb pdb:1SBM|rcsb pdb:1SDQ|rcsb pdb:1SOG|rcsb pdb:1STQ|rcsb pdb:1U74|rcsb pdb:1U75|rcsb pdb:1Z53|rcsb pdb:1ZBY|rcsb pdb:1ZBZ|rcsb pdb:2ANZ|rcsb pdb:2AQD|rcsb pdb:2AS1|rcsb pdb:2AS2|rcsb pdb:2AS3|rcsb pdb:2AS4|rcsb pdb:2AS6|rcsb pdb:2B0Z|rcsb pdb:2B10|rcsb pdb:2B11|rcsb pdb:2B12|rcsb pdb:2BCN|rcsb pdb:2CCP|rcsb pdb:2CEP|rcsb pdb:2CYP|rcsb pdb:2EUN|rcsb pdb:2EUO|rcsb pdb:2EUP|rcsb pdb:2EUQ|rcsb pdb:2EUR|rcsb pdb:2EUS|rcsb pdb:2EUT|rcsb pdb:2EUU|rcsb pdb:2GB8|rcsb pdb:2IA8|rcsb pdb:2ICV|rcsb pdb:2JTI|rcsb pdb:2N18|rcsb pdb:2PCB|rcsb pdb:2PCC|rcsb pdb:2RBT|rcsb pdb:2RBU|rcsb pdb:2RBV|rcsb pdb:2RBW|rcsb pdb:2RBX|rcsb pdb:2RBY|rcsb pdb:2RBZ|rcsb pdb:2RC0|rcsb pdb:2RC1|rcsb pdb:2RC2|rcsb pdb:2V23|rcsb pdb:2V2E|rcsb pdb:2X07|rcsb pdb:2X08|rcsb pdb:2XIL|rcsb pdb:2XJ5|rcsb pdb:2XJ8|rcsb pdb:2Y5A|rcsb pdb:2YCG|rcsb pdb:3CCP|rcsb pdb:3CCX|rcsb pdb:3E2N|rcsb pdb:3E2O|rcsb pdb:3EXB|rcsb pdb:3M23|rcsb pdb:3M25|rcsb pdb:3M26|rcsb pdb:3M27|rcsb pdb:3M28|rcsb pdb:3M29|rcsb pdb:3M2A|rcsb pdb:1CMU|rcsb pdb:3M2B|rcsb pdb:3M2C|rcsb pdb:3M2D|rcsb pdb:3M2E|rcsb pdb:3M2F|rcsb pdb:3M2G|rcsb pdb:3M2H|rcsb pdb:3M2I|rcsb pdb:3R98|rcsb pdb:3R99|rcsb pdb:4A6Z|rcsb pdb:4A71|rcsb pdb:4A78|rcsb pdb:4A7M|rcsb pdb:4CCP|rcsb pdb:4CCX|rcsb pdb:4CVI|rcsb pdb:4CVJ|rcsb pdb:4JB4|rcsb pdb:4NFG|rcsb pdb:4P4Q|rcsb pdb:4XV4|rcsb pdb:4XV5|rcsb pdb:4XV6|rcsb pdb:4XV7|rcsb pdb:4XV8|rcsb pdb:4XVA|rcsb pdb:5CCP|rcsb pdb:5CIB|rcsb pdb:5CIC|rcsb pdb:5CID|rcsb pdb:5CIE|rcsb pdb:5CIF|rcsb pdb:5CIG|rcsb pdb:5CIH|rcsb pdb:5D6M|rcsb pdb:5EJT|rcsb pdb:5EJX|rcsb pdb:6CCP|rcsb pdb:6H08|rcsb pdb:6P41|rcsb pdb:6P42|rcsb pdb:6P43|rcsb pdb:6Y1T|rcsb pdb:6Y2Y|rcsb pdb:7CCP	-	-	crc64:A5D26385DA6F0A0B	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:2TJ7rZKQNb5hH5gz9i+ujOEOIOg9606	rogid:LkPXY1wuYoCFzMQPSsAtXZrRi8w559292	intact-crc:54D416A1F3836269|rigid:/CtEOzSMFSlCAlHj1MH2wk8S2PA	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P32902	uniprotkb:Q96ED9-2	intact:EBI-16248|ensemblfungi:YHL004W|uniprotkb:D3DKR0	intact:EBI-10961706|ensembl:ENSP00000264827	psi-mi:rt04_yeast(display_long)|uniprotkb:MRP4(gene name)|psi-mi:MRP4(display_short)|uniprotkb:MRP4A(gene name synonym)|uniprotkb:Mitochondrial small ribosomal subunit protein uS2m(gene name synonym)|uniprotkb:YHL004W(locus name)	psi-mi:q96ed9-2(display_long)|uniprotkb:HOOK2(gene name)|psi-mi:HOOK2(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553612|imex:IM-24995-3974	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YHL004W(gene)|ensemblfungi:YHL004W_mRNA(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR001865(Ribosomal protein S2)|interpro:IPR005706(Ribosomal protein S2, bacterial-type)|interpro:IPR018130|interpro:IPR023591|rcsb pdb:5MRC|rcsb pdb:5MRE|rcsb pdb:5MRF|refseq:NP_011859.1|sgd:S000000996|dip:DIP-5035N|mint:P32902	ensembl:ENSG00000095066(gene)|ensembl:ENST00000264827(transcript)|intact:EBI-743290(isoform-parent)|uniprotkb:Q96ED9-2(isoform-parent)	-	crc64:81A1CB33134BC559	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:BlL3W6HUN+uAKF/AxwlV1zT5YZQ559292	rogid:aJZ/iDJpRk5dFL1NiouLuTjnOnc9606	intact-crc:C2091CAF095BCDAC|rigid:mdXrbh47M7UccastJZrUUg9uqFo	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96ED9-2	uniprotkb:O13541	intact:EBI-10961706|ensembl:ENSP00000264827	intact:EBI-11522678|ensemblfungi:YLR280C	psi-mi:q96ed9-2(display_long)|uniprotkb:HOOK2(gene name)|psi-mi:HOOK2(display_short)	psi-mi:yl280_yeast(display_long)|uniprotkb:YLR280C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553608|imex:IM-24995-3973	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000095066(gene)|ensembl:ENST00000264827(transcript)|intact:EBI-743290(isoform-parent)|uniprotkb:Q96ED9-2(isoform-parent)	ensemblfungi:YLR280C(gene)|ensemblfungi:YLR280C_mRNA(transcript)|sgd:S000004270	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/03/16	rogid:aJZ/iDJpRk5dFL1NiouLuTjnOnc9606	rogid:tBIn1i72eUTn5Ht00WY4yxkAAFU559292	intact-crc:0B6BA82F75CBC830|rigid:Zg6EYZUtXKY0+thghDqrLPJuSnw	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P24280	uniprotkb:Q96DZ9-2	intact:EBI-16535|uniprotkb:D6VZQ3|ensemblfungi:YMR079W	intact:EBI-11522780|ensembl:ENSP00000352270|ensembl:ENSP00000497215	psi-mi:sec14_yeast(display_long)|uniprotkb:SEC14(gene name)|psi-mi:SEC14(display_short)|uniprotkb:Phosphatidylinositol/phosphatidylcholine transfer protein(gene name synonym)|uniprotkb:PIT1(gene name synonym)|uniprotkb:YM9582.04(orf name)|uniprotkb:YMR079W(locus name)	psi-mi:q96dz9-2(display_long)|uniprotkb:CMTM5(gene name)|psi-mi:CMTM5(display_short)|uniprotkb:CKLFSF5(gene name synonym)|uniprotkb:Chemokine-like factor superfamily member 5(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553592|imex:IM-24995-3969	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013796.1|sgd:S000004684|ensemblfungi:YMR079W(gene)|ensemblfungi:YMR079W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0008525"(phosphatidylcholine transporter activity)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0008526"(phosphatidylinositol transfer activity)|go:"GO:0015914"(phospholipid transport)|go:"GO:0030437"(ascospore formation)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0046488"(phosphatidylinositol metabolic process)|go:"GO:0048194"(Golgi vesicle budding)|go:"GO:1901352"(negative regulation of phosphatidylglycerol biosynthetic process)|go:"GO:2001246"(negative regulation of phosphatidylcholine biosynthetic process)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR011074(Phosphatidylinositol transfer protein-like, N-terminal)|interpro:IPR036273|interpro:IPR036865|rcsb pdb:1AUA|rcsb pdb:6F0E|dip:DIP-1610N|mint:P24280	ensembl:ENSG00000166091(gene)|ensembl:ENST00000359320(transcript)|ensembl:ENST00000649278(transcript)|intact:EBI-2548702(isoform-parent)|uniprotkb:Q96DZ9-2(isoform-parent)	-	crc64:CCB69404A8A0963B	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:6KY0fOn92xmZkZBq10NHRCWtd7w559292	rogid:2TJ7rZKQNb5hH5gz9i+ujOEOIOg9606	intact-crc:03766AF062756D58|rigid:L/SnJTuS/SdJO7xn0y/aL4LubYI	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P38148	uniprotkb:Q96ED9-2	intact:EBI-21161|uniprotkb:D6VQS2|ensemblfungi:YBR276C	intact:EBI-10961706|ensembl:ENSP00000264827	psi-mi:pps1_yeast(display_long)|uniprotkb:YBR2013(orf name)|uniprotkb:YBR276C(locus name)|uniprotkb:PPS1(gene name)|psi-mi:PPS1(display_short)	psi-mi:q96ed9-2(display_long)|uniprotkb:HOOK2(gene name)|psi-mi:HOOK2(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553600|imex:IM-24995-3971	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009835.3|sgd:S000000480|mint:P38148|dip:DIP-6546N|ensemblfungi:YBR276C(gene)|ensemblfungi:YBR276C_mRNA(transcript)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0008138"(protein tyrosine/serine/threonine phosphatase activity)|go:"GO:0033260"(nuclear DNA replication)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR000340(Protein-tyrosine phosphatase, dual specificity)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR020422|interpro:IPR029021	ensembl:ENSG00000095066(gene)|ensembl:ENST00000264827(transcript)|intact:EBI-743290(isoform-parent)|uniprotkb:Q96ED9-2(isoform-parent)	-	crc64:17840CF7256EF785	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:wB3u8/rxsyTrBOJKCyqomBBHGyE559292	rogid:aJZ/iDJpRk5dFL1NiouLuTjnOnc9606	intact-crc:65A54B909BE29611|rigid:G1FQB0O5hccyrpSsh+7wLum1r9I	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96DZ9-2	uniprotkb:P04819	intact:EBI-11522780|ensembl:ENSP00000352270|ensembl:ENSP00000497215	intact:EBI-5991|uniprotkb:Q12736|uniprotkb:D6VRI7|ensemblfungi:YDL164C	psi-mi:q96dz9-2(display_long)|uniprotkb:CMTM5(gene name)|psi-mi:CMTM5(display_short)|uniprotkb:CKLFSF5(gene name synonym)|uniprotkb:Chemokine-like factor superfamily member 5(gene name synonym)	psi-mi:dnli1_yeast(display_long)|uniprotkb:YDL164C(locus name)|uniprotkb:CDC9(gene name)|psi-mi:CDC9(display_short)|uniprotkb:DNA ligase I(gene name synonym)|uniprotkb:Polydeoxyribonucleotide synthase [ATP] 1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553596|imex:IM-24995-3970	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000166091(gene)|ensembl:ENST00000359320(transcript)|ensembl:ENST00000649278(transcript)|intact:EBI-2548702(isoform-parent)|uniprotkb:Q96DZ9-2(isoform-parent)	refseq:NP_010117.1|sgd:S000002323|dip:DIP-5630N|mint:P04819|ensemblfungi:YDL164C(gene)|ensemblfungi:YDL164C_mRNA(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003677"(DNA binding)|go:"GO:0003910"("DNA ligase (ATP) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006266"(DNA ligation)|go:"GO:0006273"(lagging strand elongation)|go:"GO:0006284"(base-excision repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0035753"(maintenance of DNA trinucleotide repeats)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:0071897"(DNA biosynthetic process)|go:"GO:1903461"(Okazaki fragment processing involved in mitotic DNA replication)|interpro:IPR000977(ATP-dependent DNA ligase)|interpro:IPR012308(DNA ligase, N-terminal)|interpro:IPR012309(ATP dependent DNA ligase, C-terminal)|interpro:IPR012310(ATP dependent DNA ligase, central)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR016059(ATP-dependent DNA ligase, conserved site)|interpro:IPR036599|rcsb pdb:2OD8|reactome:R-SCE-5358565|reactome:R-SCE-5358606|reactome:R-SCE-6782210|reactome:R-SCE-69183	-	-	crc64:B7C2ECAF5C61CAE7	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:2TJ7rZKQNb5hH5gz9i+ujOEOIOg9606	rogid:sl00ubCmkTFwW2bznucqEF60I3M559292	intact-crc:8F8E0E88BA24C290|rigid:3eAaeCLoVTYQ+m29PX6da1v9rFg	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96ED9-2	uniprotkb:P32571	intact:EBI-10961706|ensembl:ENSP00000264827	intact:EBI-19840|uniprotkb:D6VS55|ensemblfungi:YDR069C	psi-mi:q96ed9-2(display_long)|uniprotkb:HOOK2(gene name)|psi-mi:HOOK2(display_short)	psi-mi:ubp4_yeast(display_long)|uniprotkb:DOA4(gene name)|psi-mi:DOA4(display_short)|uniprotkb:MUT4(gene name synonym)|uniprotkb:SSV7(gene name synonym)|uniprotkb:YDR069C(locus name)|uniprotkb:YD9609.23C(orf name)|uniprotkb:YD8554.02C(orf name)|uniprotkb:D4270(orf name)|uniprotkb:NPI2(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 4(gene name synonym)|uniprotkb:Deubiquitinating enzyme 4(gene name synonym)|uniprotkb:Vacuole biogenesis protein SSV7(gene name synonym)|uniprotkb:Ubiquitin thioesterase 4(gene name synonym)|uniprotkb:DOS1(gene name synonym)|uniprotkb:UBP4(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553604|imex:IM-24995-3972	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000095066(gene)|ensembl:ENST00000264827(transcript)|intact:EBI-743290(isoform-parent)|uniprotkb:Q96ED9-2(isoform-parent)	sgd:S000002476|ensemblfungi:YDR069C(gene)|ensemblfungi:YDR069C_mRNA(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005739"(mitochondrion)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0010992"(ubiquitin recycling)|go:"GO:0010995"(free ubiquitin chain depolymerization)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0031902"(late endosome membrane)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0070676"(intralumenal vesicle formation)|go:"GO:1904669"(ATP export)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR001763(Rhodanese-like)|interpro:IPR018200|interpro:IPR028889|interpro:IPR036873|interpro:IPR038765|refseq:NP_010354.3|dip:DIP-5298N|mint:P32571	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:aJZ/iDJpRk5dFL1NiouLuTjnOnc9606	rogid:UTBSWmpygyxo1ygxp/sQ8wgqnMo559292	intact-crc:1FF8EB0ADD74E205|rigid:u6BwzFlMwt2j4xi/nZM8QYjxRkI	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96EV8	uniprotkb:P48232	intact:EBI-465804|uniprotkb:Q5THY3|uniprotkb:Q5THY4|uniprotkb:Q96NV2|intact:EBI-28986386|ensembl:ENSP00000341680|uniprotkb:Q9H0U2|uniprotkb:Q9H3J5|uniprotkb:A8K3V3	intact:EBI-28775|uniprotkb:D6W193|ensemblfungi:YNL086W	psi-mi:dtbp1_human(display_long)|uniprotkb:My031(orf name)|uniprotkb:DTNBP1(gene name)|psi-mi:DTNBP1(display_short)|uniprotkb:Dystrobrevin-binding protein 1(gene name synonym)|uniprotkb:Hermansky-Pudlak syndrome 7 protein(gene name synonym)|uniprotkb:Dysbindin-1(gene name synonym)|uniprotkb:BLOC1S8(gene name synonym)|uniprotkb:Biogenesis of lysosome-related organelles complex 1 subunit 8(gene name synonym)	psi-mi:snapn_yeast(display_long)|uniprotkb:YNL086W(locus name)|uniprotkb:N2254(orf name)|uniprotkb:SNN1(gene name)|psi-mi:SNN1(display_short)|uniprotkb:SNAPIN-like protein 1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553632|imex:IM-24995-3979	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000047579(gene)|ensembl:ENST00000344537(transcript)|go:"GO:0001956"(positive regulation of neurotransmitter secretion)|go:"GO:0005634"(nucleus)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007596"(blood coagulation)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014059"(regulation of dopamine secretion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016528"(sarcoplasm)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0030496"(midbody)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032438"(melanosome organization)|go:"GO:0033162"(melanosome membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0043005"(neuron projection)|go:"GO:0043197"(dendritic spine)|go:"GO:0005737"(cytoplasm)|go:"GO:0043506"(regulation of JUN kinase activity)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0060155"(platelet dense granule organization)|go:"GO:0060159"(regulation of dopamine receptor signaling pathway)|go:"GO:0071901"(negative regulation of protein serine/threonine kinase activity)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR007531(Dysbindin)|reactome:R-HSA-432722|go:"GO:0048490"(anterograde synaptic vesicle transport)|refseq:NP_115498.2|refseq:NP_898861.1|refseq:NP_001258597.1|refseq:NP_001258598.1|ensembl:ENST00000338950|ensembl:ENSP00000344718|ensembl:ENSP00000341680|refseq:NP_001258596.1	refseq:NP_014313.1|sgd:S000005030|dip:DIP-1188N|mint:P48232|ensemblfungi:YNL086W(gene)|ensemblfungi:YNL086W_mRNA(transcript)|go:"GO:0005768"(endosome)|go:"GO:0007032"(endosome organization)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0032880"(regulation of protein localization)	-	-	crc64:33200D2F0F729DA1	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:PBwxp1vobm9l5yGoqev97lzkMHg9606	rogid:XCPaHuGC9oKD/3W0gY5ZY8jKtFs559292	intact-crc:6294CCF203EB7B58|rigid:G5QXP+d4EP28p40fQo/bbxOmhiQ	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P32610	uniprotkb:Q96EV8	intact:EBI-20264|uniprotkb:D3DLJ9|ensemblfungi:YEL051W	intact:EBI-465804|uniprotkb:Q5THY3|uniprotkb:Q5THY4|uniprotkb:Q96NV2|intact:EBI-28986386|ensembl:ENSP00000341680|uniprotkb:Q9H0U2|uniprotkb:Q9H3J5|uniprotkb:A8K3V3	psi-mi:vatd_yeast(display_long)|uniprotkb:VMA8(gene name)|psi-mi:VMA8(display_short)|uniprotkb:YEL051W(locus name)|uniprotkb:SYGP-ORF11(orf name)|uniprotkb:Vacuolar proton pump subunit D(gene name synonym)	psi-mi:dtbp1_human(display_long)|uniprotkb:My031(orf name)|uniprotkb:DTNBP1(gene name)|psi-mi:DTNBP1(display_short)|uniprotkb:Dystrobrevin-binding protein 1(gene name synonym)|uniprotkb:Hermansky-Pudlak syndrome 7 protein(gene name synonym)|uniprotkb:Dysbindin-1(gene name synonym)|uniprotkb:BLOC1S8(gene name synonym)|uniprotkb:Biogenesis of lysosome-related organelles complex 1 subunit 8(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553628|imex:IM-24995-3978	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010863.1|sgd:S000000777|ensemblfungi:YEL051W(gene)|ensemblfungi:YEL051W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0016471"(vacuolar proton-transporting V-type ATPase complex)|go:"GO:0033176"(proton-transporting V-type ATPase complex)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR002699(ATPase, V1/A1 complex, subunit D)|rcsb pdb:3J9T|rcsb pdb:3J9U|rcsb pdb:3J9V|rcsb pdb:4RND|rcsb pdb:5BW9|rcsb pdb:5D80|rcsb pdb:5VOX|rcsb pdb:5VOY|rcsb pdb:5VOZ|rcsb pdb:6O7V|rcsb pdb:6O7W|rcsb pdb:6O7X|reactome:R-SCE-1222556|reactome:R-SCE-6798695|reactome:R-SCE-77387|reactome:R-SCE-917977|reactome:R-SCE-9639288|dip:DIP-2959N|mint:P32610	ensembl:ENSG00000047579(gene)|ensembl:ENST00000344537(transcript)|go:"GO:0001956"(positive regulation of neurotransmitter secretion)|go:"GO:0005634"(nucleus)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007596"(blood coagulation)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014059"(regulation of dopamine secretion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016528"(sarcoplasm)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0030496"(midbody)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032438"(melanosome organization)|go:"GO:0033162"(melanosome membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0043005"(neuron projection)|go:"GO:0043197"(dendritic spine)|go:"GO:0005737"(cytoplasm)|go:"GO:0043506"(regulation of JUN kinase activity)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0060155"(platelet dense granule organization)|go:"GO:0060159"(regulation of dopamine receptor signaling pathway)|go:"GO:0071901"(negative regulation of protein serine/threonine kinase activity)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR007531(Dysbindin)|reactome:R-HSA-432722|go:"GO:0048490"(anterograde synaptic vesicle transport)|refseq:NP_115498.2|refseq:NP_898861.1|refseq:NP_001258597.1|refseq:NP_001258598.1|ensembl:ENST00000338950|ensembl:ENSP00000344718|ensembl:ENSP00000341680|refseq:NP_001258596.1	-	crc64:FDE93E1FAF0AEC5B	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:rrwRno7lCnDeTNwawONkGwV8Hkg559292	rogid:PBwxp1vobm9l5yGoqev97lzkMHg9606	intact-crc:4491AAEAFD7BFBB1|rigid:SIIATUHtRJRLyRIKE2irBgkXGmA	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P17695	uniprotkb:Q96EQ0	intact:EBI-7699|uniprotkb:Q6B234|uniprotkb:D6VTD4|ensemblfungi:YDR513W	intact:EBI-744081|ensembl:ENSP00000370395	psi-mi:glrx2_yeast(display_long)|uniprotkb:TTR(gene name synonym)|uniprotkb:GRX2(gene name)|psi-mi:GRX2(display_short)|uniprotkb:Thioltransferase(gene name synonym)|uniprotkb:Glutathione-dependent oxidoreductase 2(gene name synonym)|uniprotkb:TTR1(gene name synonym)|uniprotkb:D9719.17(orf name)|uniprotkb:YDR513W(locus name)	psi-mi:sgtb_human(display_long)|uniprotkb:Beta-SGT(gene name synonym)|uniprotkb:Small glutamine-rich protein with tetratricopeptide repeats 2(gene name synonym)|uniprotkb:SGTB(gene name)|psi-mi:SGTB(display_short)|uniprotkb:SGT2(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553616|imex:IM-24995-3975	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010801.1|sgd:S000002921|dip:DIP-5271N|ensemblfungi:YDR513W(gene)|ensemblfungi:YDR513W_mRNA(transcript)|go:"GO:0004362"("glutathione-disulfide reductase (NADPH) activity")|go:"GO:0004364"(glutathione transferase activity)|go:"GO:0004602"(glutathione peroxidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0015036"(disulfide oxidoreductase activity)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0097573"(glutathione oxidoreductase activity)|interpro:IPR002109(Glutaredoxin)|interpro:IPR011767(Glutaredoxin active site)|interpro:IPR011899(Glutaredoxin, eukaryotic and viruses)|interpro:IPR014025(Glutaredoxin subgroup)|interpro:IPR036249|rcsb pdb:3CTF|rcsb pdb:3CTG|rcsb pdb:3D4M|rcsb pdb:3D5J	refseq:NP_061945.1|refseq:XP_005248605.1|ensembl:ENSG00000197860(gene)|ensembl:ENST00000381007(transcript)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0072380"(TRC complex)|go:"GO:1903646"(positive regulation of chaperone-mediated protein folding)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR032374	-	crc64:99A79B87695B2266	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:u4CcRMaG3tJhhzqf3yNKktvKfv4559292	rogid:emIgH8U/yVmXT00Ty9yybIqQqas9606	intact-crc:428E7A458A8068C4|rigid:UOpuro/yb07aRANWDzKKbv6TiI8	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P35176	uniprotkb:Q96EQ0	intact:EBI-5458|uniprotkb:D6VST3|ensemblfungi:YDR304C	intact:EBI-744081|ensembl:ENSP00000370395	psi-mi:cypd_yeast(display_long)|uniprotkb:CPR5(gene name)|psi-mi:CPR5(display_short)|uniprotkb:YDR304C(locus name)|uniprotkb:D9740.14(orf name)|uniprotkb:CYP5(gene name synonym)|uniprotkb:CYPD(gene name synonym)|uniprotkb:Cyclophilin D(gene name synonym)|uniprotkb:Rotamase D(gene name synonym)	psi-mi:sgtb_human(display_long)|uniprotkb:Beta-SGT(gene name synonym)|uniprotkb:Small glutamine-rich protein with tetratricopeptide repeats 2(gene name synonym)|uniprotkb:SGTB(gene name)|psi-mi:SGTB(display_short)|uniprotkb:SGT2(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553620|imex:IM-24995-3976	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002712|refseq:NP_010590.3|dip:DIP-5222N|mint:P35176|ensemblfungi:YDR304C(gene)|ensemblfungi:YDR304C_mRNA(transcript)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006457"(protein folding)|go:"GO:0016018"(cyclosporin A binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|interpro:IPR020892|interpro:IPR029000	refseq:NP_061945.1|refseq:XP_005248605.1|ensembl:ENSG00000197860(gene)|ensembl:ENST00000381007(transcript)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0072380"(TRC complex)|go:"GO:1903646"(positive regulation of chaperone-mediated protein folding)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR032374	-	crc64:F4861424C8443B58	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:aCn3loYoSVWfy5Tb5i+MsOHcUEo559292	rogid:emIgH8U/yVmXT00Ty9yybIqQqas9606	intact-crc:713636A343A3B504|rigid:moBP3cAFyw6oKkz6/z7bg7JEHGU	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q04110	uniprotkb:Q96EV8	intact:EBI-37150|uniprotkb:D6VT71|ensemblfungi:YDR446W	intact:EBI-465804|uniprotkb:Q5THY3|uniprotkb:Q5THY4|uniprotkb:Q96NV2|intact:EBI-28986386|ensembl:ENSP00000341680|uniprotkb:Q9H0U2|uniprotkb:Q9H3J5|uniprotkb:A8K3V3	psi-mi:ecm11_yeast(display_long)|uniprotkb:ECM11(gene name)|psi-mi:ECM11(display_short)|uniprotkb:YDR446W(locus name)|uniprotkb:D9461.31(orf name)|uniprotkb:Extracellular mutant protein 11(gene name synonym)	psi-mi:dtbp1_human(display_long)|uniprotkb:My031(orf name)|uniprotkb:DTNBP1(gene name)|psi-mi:DTNBP1(display_short)|uniprotkb:Dystrobrevin-binding protein 1(gene name synonym)|uniprotkb:Hermansky-Pudlak syndrome 7 protein(gene name synonym)|uniprotkb:Dysbindin-1(gene name synonym)|uniprotkb:BLOC1S8(gene name synonym)|uniprotkb:Biogenesis of lysosome-related organelles complex 1 subunit 8(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553624|imex:IM-24995-3977	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002854|refseq:NP_010734.1|dip:DIP-2060N|ensemblfungi:YDR446W(gene)|ensemblfungi:YDR446W_mRNA(transcript)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0005634"(nucleus)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0070193"(synaptonemal complex organization)|go:"GO:0071555"(cell wall organization)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|interpro:IPR029178	ensembl:ENSG00000047579(gene)|ensembl:ENST00000344537(transcript)|go:"GO:0001956"(positive regulation of neurotransmitter secretion)|go:"GO:0005634"(nucleus)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007596"(blood coagulation)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014059"(regulation of dopamine secretion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016528"(sarcoplasm)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0030496"(midbody)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032438"(melanosome organization)|go:"GO:0033162"(melanosome membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0043005"(neuron projection)|go:"GO:0043197"(dendritic spine)|go:"GO:0005737"(cytoplasm)|go:"GO:0043506"(regulation of JUN kinase activity)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0060155"(platelet dense granule organization)|go:"GO:0060159"(regulation of dopamine receptor signaling pathway)|go:"GO:0071901"(negative regulation of protein serine/threonine kinase activity)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR007531(Dysbindin)|reactome:R-HSA-432722|go:"GO:0048490"(anterograde synaptic vesicle transport)|refseq:NP_115498.2|refseq:NP_898861.1|refseq:NP_001258597.1|refseq:NP_001258598.1|ensembl:ENST00000338950|ensembl:ENSP00000344718|ensembl:ENSP00000341680|refseq:NP_001258596.1	-	crc64:CB6890F4EE069232	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:F5ueMuYv+ymWlt2junW3o49OB/g559292	rogid:PBwxp1vobm9l5yGoqev97lzkMHg9606	intact-crc:2FCF331C8CC13684|rigid:eqNiwv+OLd0YenZ8twdCDnpnE6U	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P38182	uniprotkb:Q96GX9	intact:EBI-2684|uniprotkb:D6VPS5|ensemblfungi:YBL078C	intact:EBI-359248|ensembl:ENSP00000379133|intact:EBI-2848621|uniprotkb:Q6PJX6|uniprotkb:Q8WVU2|uniprotkb:Q96HK2|uniprotkb:Q9Y318|uniprotkb:A8K9D3	psi-mi:atg8_yeast(display_long)|uniprotkb:ATG8(gene name)|psi-mi:ATG8(display_short)|uniprotkb:APG8(gene name synonym)|uniprotkb:AUT7(gene name synonym)|uniprotkb:YBL078C(locus name)|uniprotkb:YBL0732(orf name)|uniprotkb:CVT5(gene name synonym)|uniprotkb:Autophagy-related ubiquitin-like modifier ATG8(gene name synonym)|uniprotkb:Cytoplasm to vacuole targeting protein 5(gene name synonym)	psi-mi:mtnb_human(display_long)|uniprotkb:APIP(gene name)|psi-mi:APIP(display_short)|uniprotkb:CGI-29(orf name)|uniprotkb:APAF1-interacting protein(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553656|imex:IM-24995-3985	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000000174|refseq:NP_009475.1|dip:DIP-1197N|mint:P38182|ensemblfungi:YBL078C(gene)|ensemblfungi:YBL078C_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006914"(autophagy)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0008429"(phosphatidylethanolamine binding)|go:"GO:0016236"(macroautophagy)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0031386"(protein tag)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0033110"(Cvt vesicle membrane)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0034629"|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|go:"GO:0061025"(membrane fusion)|go:"GO:0061709"(reticulophagy)|go:"GO:0071211"(protein targeting to vacuole involved in autophagy)|go:"GO:0120095"(vacuole-isolation membrane contact site)|go:"GO:1905153"(regulation of membrane invagination)|interpro:IPR004241("Light chain 3 (LC3)")|interpro:IPR029071|rcsb pdb:2KQ7|rcsb pdb:2KWC|rcsb pdb:2LI5|rcsb pdb:2ZPN|rcsb pdb:3RUI|rcsb pdb:3VH3|rcsb pdb:3VH4|rcsb pdb:3VXW|rcsb pdb:5YEC|rcsb pdb:6AAG|rcsb pdb:6WY6|rcsb pdb:7BRN|reactome:R-SCE-1632852|reactome:R-SCE-8854214|reactome:R-SCE-8934903	ensembl:ENSG00000149089(gene)|ensembl:ENST00000395787(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019284"(L-methionine salvage from S-adenosylmethionine)|go:"GO:0019509"(L-methionine salvage from methylthioadenosine)|refseq:NP_057041.2|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0046570"(methylthioribulose 1-phosphate dehydratase activity)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0070269"(pyroptosis)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|interpro:IPR001303(Class II aldolase/adducin, N-terminal)|interpro:IPR017714(Methylthioribulose-1-phosphate dehydratase)|interpro:IPR027514|interpro:IPR036409|rcsb pdb:4M6R|reactome:R-HSA-111458|reactome:R-HSA-1237112|reactome:R-HSA-9627069	-	crc64:1246CEFF5A038819	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:UlmpBW3JgdYFHLkZCQeJeb7DpK4559292	rogid:k+IcLEB6jPgZW0Zl597PZyGbHH49606	intact-crc:BA927DD217C97F60|rigid:wgy+lOhNd+Qn5eTzjT8SW6Hbl6g	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P52870	uniprotkb:Q96G97-4	intact:EBI-16410|ensemblfungi:YER087C-B|uniprotkb:D3DLZ4	intact:EBI-10178113|ensembl:ENSP00000354032|ensembl:ENSP00000433888|ensembl:ENSP00000505838	psi-mi:sc6b1_yeast(display_long)|uniprotkb:Sec61 complex subunit SBH1(gene name synonym)|uniprotkb:YER087BC(orf name)|uniprotkb:YER087C-B(locus name)|uniprotkb:SBH1(gene name)|psi-mi:SBH1(display_short)|uniprotkb:SEB1(gene name synonym)|uniprotkb:Sec61 complex subunit beta(gene name synonym)	psi-mi:q96g97-4(display_long)|uniprotkb:Bernardinelli-Seip congenital lipodystrophy type 2 protein(gene name synonym)|uniprotkb:BSCL2(gene name)|psi-mi:BSCL2(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553652|imex:IM-24995-3984	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YER087C-B(gene)|ensemblfungi:YER087C-B_mRNA(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|interpro:IPR016482(Preprotein translocase Sec, Sec61-beta subunit, eukarya)|interpro:IPR030671|rcsb pdb:6N3Q|rcsb pdb:6ND1|rcsb pdb:7AFT|rcsb pdb:7KAH|rcsb pdb:7KAI|sgd:S000002128|rcsb pdb:7KAJ|rcsb pdb:7KAO|rcsb pdb:7KAP|rcsb pdb:7KAQ|rcsb pdb:7KAR|rcsb pdb:7KAS|rcsb pdb:7KAT|rcsb pdb:7KAU|rcsb pdb:7KB5|refseq:NP_011011.3|dip:DIP-5681N|mint:P52870	ensembl:ENSG00000168000(gene)|ensembl:ENST00000360796(transcript)|ensembl:ENST00000524862(transcript)|ensembl:ENST00000679883(transcript)|intact:EBI-741806(isoform-parent)|uniprotkb:Q96G97-4(isoform-parent)	-	-	isoform-comment:No experimental confirmation available.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:9cYnDPhmMpAOdB2GV5TxikzpjI0559292	rogid:Kewl3FQYPECmEGogRRGyAethllI9606	intact-crc:FFFBE98AD1E066A6|rigid:9CIBlAnJj1YRJCicuLOS1cjr4Xc	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96EY1-3	uniprotkb:P38340	intact:EBI-11526226|ensembl:ENSP00000393970	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:q96ey1-3(display_long)|uniprotkb:DnaJ protein Tid-1(gene name synonym)|uniprotkb:HCA57(gene name synonym)|uniprotkb:Hepatocellular carcinoma-associated antigen 57(gene name synonym)|uniprotkb:TID1(gene name synonym)|uniprotkb:Tumorous imaginal discs protein Tid56 homolog(gene name synonym)|uniprotkb:DNAJA3(gene name)|psi-mi:DNAJA3(display_short)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553636|imex:IM-24995-3980	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-356767(isoform-parent)|ensembl:ENSG00000103423(gene)|ensembl:ENST00000431375(transcript)|uniprotkb:Q96EY1-3(isoform-parent)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F	-	isoform-comment:"Ref.3 (BAG58345) sequence is in conflict in position: 33:Y->H."	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:nMH4IaOZYO5w5bh+cdX4LoPSisc9606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:DEA97782550AE2BB|rigid:k6U6xtX0na4XLi0xPmqP91pJVWY	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96EY1-3	uniprotkb:P54784	intact:EBI-11526226|ensembl:ENSP00000393970	intact:EBI-12568|uniprotkb:D6VZA8|ensemblfungi:YML065W	psi-mi:q96ey1-3(display_long)|uniprotkb:DnaJ protein Tid-1(gene name synonym)|uniprotkb:HCA57(gene name synonym)|uniprotkb:Hepatocellular carcinoma-associated antigen 57(gene name synonym)|uniprotkb:TID1(gene name synonym)|uniprotkb:Tumorous imaginal discs protein Tid56 homolog(gene name synonym)|uniprotkb:DNAJA3(gene name)|psi-mi:DNAJA3(display_short)	psi-mi:orc1_yeast(display_long)|uniprotkb:ORC1(gene name)|psi-mi:ORC1(display_short)|uniprotkb:YML065W(locus name)|uniprotkb:Origin recognition complex 120 kDa subunit(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553644|imex:IM-24995-3982	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-356767(isoform-parent)|ensembl:ENSG00000103423(gene)|ensembl:ENST00000431375(transcript)|uniprotkb:Q96EY1-3(isoform-parent)	rcsb pdb:6WGG|rcsb pdb:6WGI|rcsb pdb:7MCA|reactome:R-SCE-68616|rcsb pdb:6WGC|reactome:R-SCE-68949|reactome:R-SCE-68962|ensemblfungi:YML065W(gene)|ensemblfungi:YML065W_mRNA(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031491"(nucleosome binding)|go:"GO:0033314"(mitotic DNA replication checkpoint signaling)|go:"GO:0043007"(maintenance of rDNA)|go:"GO:0046872"(metal ion binding)|interpro:IPR001025(Bromo adjacent region)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR020793|interpro:IPR027417|interpro:IPR041083|interpro:IPR043151|rcsb pdb:1M4Z|rcsb pdb:1ZBX|rcsb pdb:1ZHI|rcsb pdb:5V8F|rcsb pdb:5ZR1|rcsb pdb:6OM3|rcsb pdb:6RQC|refseq:NP_013646.1|sgd:S000004530|dip:DIP-2284N|mint:P54784	-	isoform-comment:"Ref.3 (BAG58345) sequence is in conflict in position: 33:Y->H."	crc64:BDAA9D3E40B4B76A	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:nMH4IaOZYO5w5bh+cdX4LoPSisc9606	rogid:ZTOvWqU+Rxwll7cRwOUsRqJC08M559292	intact-crc:823850CA7BB38FE5|rigid:uyQdY0emWwd3M6pHBgtdiMY4lq0	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96EY1-3	uniprotkb:P32502	intact:EBI-11526226|ensembl:ENSP00000393970	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:q96ey1-3(display_long)|uniprotkb:DnaJ protein Tid-1(gene name synonym)|uniprotkb:HCA57(gene name synonym)|uniprotkb:Hepatocellular carcinoma-associated antigen 57(gene name synonym)|uniprotkb:TID1(gene name synonym)|uniprotkb:Tumorous imaginal discs protein Tid56 homolog(gene name synonym)|uniprotkb:DNAJA3(gene name)|psi-mi:DNAJA3(display_short)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553640|imex:IM-24995-3981	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-356767(isoform-parent)|ensembl:ENSG00000103423(gene)|ensembl:ENST00000431375(transcript)|uniprotkb:Q96EY1-3(isoform-parent)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731	-	isoform-comment:"Ref.3 (BAG58345) sequence is in conflict in position: 33:Y->H."	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:nMH4IaOZYO5w5bh+cdX4LoPSisc9606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:D999D6CE4A7E96C8|rigid:aTXYAL3WN3g4e2tWaFZyCDv0gP0	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96EY1-3	uniprotkb:P47041	intact:EBI-11526226|ensembl:ENSP00000393970	intact:EBI-25889|uniprotkb:D6VWC4|ensemblfungi:YJL058C	psi-mi:q96ey1-3(display_long)|uniprotkb:DnaJ protein Tid-1(gene name synonym)|uniprotkb:HCA57(gene name synonym)|uniprotkb:Hepatocellular carcinoma-associated antigen 57(gene name synonym)|uniprotkb:TID1(gene name synonym)|uniprotkb:Tumorous imaginal discs protein Tid56 homolog(gene name synonym)|uniprotkb:DNAJA3(gene name)|psi-mi:DNAJA3(display_short)	psi-mi:bit61_yeast(display_long)|uniprotkb:YJL058C(locus name)|uniprotkb:J1141(orf name)|uniprotkb:61 kDa binding partner of TOR2 protein(gene name synonym)|uniprotkb:BIT61(gene name)|psi-mi:BIT61(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553648|imex:IM-24995-3983	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-356767(isoform-parent)|ensembl:ENSG00000103423(gene)|ensembl:ENST00000431375(transcript)|uniprotkb:Q96EY1-3(isoform-parent)	refseq:NP_012477.1|sgd:S000003594|dip:DIP-1444N|reactome:R-SCE-1257604|reactome:R-SCE-389357|reactome:R-SCE-5218920|ensemblfungi:YJL058C(gene)|ensemblfungi:YJL058C_mRNA(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005737"(cytoplasm)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0031932"(TORC2 complex)|go:"GO:0038203"(TORC2 signaling)|go:"GO:0071944"(cell periphery)|interpro:IPR013745(HbrB-like)|reactome:R-SCE-6804757	-	isoform-comment:"Ref.3 (BAG58345) sequence is in conflict in position: 33:Y->H."	crc64:99F0F96840311F4B	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:nMH4IaOZYO5w5bh+cdX4LoPSisc9606	rogid:H+zcKwbWL90wsmvD9TfWYmEbRwM559292	intact-crc:F20B48DBF067A195|rigid:BIUcqDzPWeKiECjMQJFdyG5lduk	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96H20-2	uniprotkb:P47142	intact:EBI-11121416|ensembl:ENSP00000290330	intact:EBI-25595|uniprotkb:D6VWS1|ensemblfungi:YJR102C	psi-mi:q96h20-2(display_long)|uniprotkb:SNF8(gene name)|psi-mi:SNF8(display_short)|uniprotkb:EAP30(gene name synonym)|uniprotkb:ELL-associated protein of 30 kDa(gene name synonym)|uniprotkb:ESCRT-II complex subunit VPS22(gene name synonym)	psi-mi:vps25_yeast(display_long)|uniprotkb:YJR102C(locus name)|uniprotkb:J1957(orf name)|uniprotkb:VPS25(gene name)|psi-mi:VPS25(display_short)|uniprotkb:VPT25(gene name synonym)|uniprotkb:ESCRT-II complex subunit VPS25(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553676|imex:IM-24995-3990	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-747719(isoform-parent)|ensembl:ENSG00000159210(gene)|ensembl:ENST00000290330(transcript)	refseq:NP_012636.1|sgd:S000003863|mint:P47142|dip:DIP-4446N|ensemblfungi:YJR102C(gene)|ensemblfungi:YJR102C_mRNA(transcript)|go:"GO:0000433"(carbon catabolite repression of transcription from RNA polymerase II promoter by glucose)|go:"GO:0000814"(ESCRT II complex)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043328"(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:1904669"(ATP export)|interpro:IPR008570(ESCRT-II complex, vps25 subunit)|interpro:IPR014041(ESCRT-II complex, vps25 subunit, N-terminal winged helix)|interpro:IPR036388|interpro:IPR036390|rcsb pdb:1U5T|rcsb pdb:1W7P|rcsb pdb:1XB4|reactome:R-SCE-917729	-	isoform-comment:No experimental confirmation available.	crc64:6A4545A8BC772CA2	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Q8Kde7wzzgiTELEbfVpV36PVV5E9606	rogid:LlNZVpWKYsWsgu0FcP2sL10lYHc559292	intact-crc:338D39228DFCF9FC|rigid:B0FGWfS0RZ18UHY60iRrpmjLYVQ	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P47142	uniprotkb:Q96H20	intact:EBI-25595|uniprotkb:D6VWS1|ensemblfungi:YJR102C	intact:EBI-747719|uniprotkb:Q8IXY3|uniprotkb:Q9UN50|ensembl:ENSP00000421380	psi-mi:vps25_yeast(display_long)|uniprotkb:YJR102C(locus name)|uniprotkb:J1957(orf name)|uniprotkb:VPS25(gene name)|psi-mi:VPS25(display_short)|uniprotkb:VPT25(gene name synonym)|uniprotkb:ESCRT-II complex subunit VPS25(gene name synonym)	psi-mi:snf8_human(display_long)|uniprotkb:ELL-associated protein of 30 kDa(gene name synonym)|uniprotkb:SNF8(gene name)|psi-mi:SNF8(display_short)|uniprotkb:EAP30(gene name synonym)|uniprotkb:ESCRT-II complex subunit VPS22(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553672|imex:IM-24995-3989	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012636.1|sgd:S000003863|mint:P47142|dip:DIP-4446N|ensemblfungi:YJR102C(gene)|ensemblfungi:YJR102C_mRNA(transcript)|go:"GO:0000433"(carbon catabolite repression of transcription from RNA polymerase II promoter by glucose)|go:"GO:0000814"(ESCRT II complex)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043328"(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:1904669"(ATP export)|interpro:IPR008570(ESCRT-II complex, vps25 subunit)|interpro:IPR014041(ESCRT-II complex, vps25 subunit, N-terminal winged helix)|interpro:IPR036388|interpro:IPR036390|rcsb pdb:1U5T|rcsb pdb:1W7P|rcsb pdb:1XB4|reactome:R-SCE-917729	refseq:NP_009172.2|refseq:NP_001304121.1|refseq:NP_001304122.1|refseq:NP_001304123.1|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010008"(endosome membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0016247"(channel regulator activity)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043328"(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055037"(recycling endosome)|go:"GO:0061635"(regulation of protein complex stability)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071985"(multivesicular body sorting pathway)|go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:1903772"(regulation of viral budding via host ESCRT complex)|interpro:IPR016689(ESCRT-2 complex, Snf8)|interpro:IPR036388|interpro:IPR036390|interpro:IPR040608|mint:Q96H20|rcsb pdb:2ZME|rcsb pdb:3CUQ|reactome:R-HSA-917729|reactome:R-HSA-9610379|ensembl:ENSG00000159210(gene)|ensembl:ENST00000502492(transcript)|go:"GO:0000814"(ESCRT II complex)	-	crc64:6A4545A8BC772CA2	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:LlNZVpWKYsWsgu0FcP2sL10lYHc559292	rogid:FyjlBpOt9okBFV8Z+g8YLUeyCm49606	intact-crc:B1CFD6FE9A9DCC48|rigid:FYnf8xbP9QsNSNXgRnwRbzuWSOE	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P40454	uniprotkb:Q96GX9	intact:EBI-25278|uniprotkb:D6VVD4|ensemblfungi:YIL153W	intact:EBI-359248|ensembl:ENSP00000379133|intact:EBI-2848621|uniprotkb:Q6PJX6|uniprotkb:Q8WVU2|uniprotkb:Q96HK2|uniprotkb:Q9Y318|uniprotkb:A8K9D3	psi-mi:ptpa1_yeast(display_long)|uniprotkb:YIL153W(locus name)|uniprotkb:RRD1(gene name)|psi-mi:RRD1(display_short)|uniprotkb:NCS1(gene name synonym)|uniprotkb:YPA1(gene name synonym)|uniprotkb:Peptidyl-prolyl cis-trans isomerase PTPA-1(gene name synonym)|uniprotkb:Phosphotyrosyl phosphatase activator 1(gene name synonym)	psi-mi:mtnb_human(display_long)|uniprotkb:APIP(gene name)|psi-mi:APIP(display_short)|uniprotkb:CGI-29(orf name)|uniprotkb:APAF1-interacting protein(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553660|imex:IM-24995-3986	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012113.1|sgd:S000001415|mint:P40454|dip:DIP-5663N|ensemblfungi:YIL153W(gene)|ensemblfungi:YIL153W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006914"(autophagy)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008160"(protein tyrosine phosphatase activator activity)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0043618"(regulation of transcription from RNA polymerase II promoter in response to stress)|interpro:IPR004327(Phosphotyrosyl phosphatase activator, PTPA)|interpro:IPR037218|interpro:IPR043170|rcsb pdb:2IXO|rcsb pdb:2IXP	ensembl:ENSG00000149089(gene)|ensembl:ENST00000395787(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019284"(L-methionine salvage from S-adenosylmethionine)|go:"GO:0019509"(L-methionine salvage from methylthioadenosine)|refseq:NP_057041.2|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0046570"(methylthioribulose 1-phosphate dehydratase activity)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0070269"(pyroptosis)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|interpro:IPR001303(Class II aldolase/adducin, N-terminal)|interpro:IPR017714(Methylthioribulose-1-phosphate dehydratase)|interpro:IPR027514|interpro:IPR036409|rcsb pdb:4M6R|reactome:R-HSA-111458|reactome:R-HSA-1237112|reactome:R-HSA-9627069	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:It2q8WlpmvLEZ1fqpRF5Fypw9Q4559292	rogid:k+IcLEB6jPgZW0Zl597PZyGbHH49606	intact-crc:FDB7751381210FC4|rigid:HYMUYXyFDqqwnxfs/MAmVdVHFVU	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P38822	uniprotkb:Q96GY0	intact:EBI-3889|uniprotkb:E9P8V2|uniprotkb:D3DL64|ensemblfungi:YHR114W	intact:EBI-5458880|uniprotkb:Q9Y372|ensembl:ENSP00000263849	psi-mi:bzz1_yeast(display_long)|uniprotkb:BZZ1(gene name)|psi-mi:BZZ1(display_short)|uniprotkb:LAS17-binding protein 7(gene name synonym)|uniprotkb:LSB7(gene name synonym)|uniprotkb:YHR114W(locus name)	psi-mi:zc21a_human(display_long)|uniprotkb:ZC2HC1A(gene name)|psi-mi:ZC2HC1A(display_short)|uniprotkb:C8orf70(gene name synonym)|uniprotkb:FAM164A(gene name synonym)|uniprotkb:CGI-62(orf name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553664|imex:IM-24995-3987	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011982.1|sgd:S000001156|dip:DIP-2143N|mint:P38822|ensemblfungi:YHR114W(gene)|ensemblfungi:YHR114W_mRNA(transcript)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006897"(endocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0009651"(response to salt stress)|go:"GO:0030479"(actin cortical patch)|go:"GO:0043332"(mating projection tip)|go:"GO:0045010"(actin nucleation)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR027267|interpro:IPR031160|interpro:IPR036028|rcsb pdb:1ZUU|rcsb pdb:2A28|reactome:R-SCE-8856828|reactome:R-SCE-9013406|reactome:R-SCE-9696270	refseq:NP_057094.2|ensembl:ENSG00000104427(gene)|ensembl:ENST00000263849(transcript)|go:"GO:0046872"(metal ion binding)|interpro:IPR026319	-	crc64:5C73DACC69611B41	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:lnoTdZ+pWCE2mDz3Ha7VQOOCfM8559292	rogid:5QYEwHhPJBrdqbU1jKnxdZFYC7c9606	intact-crc:1362AD1E73CCB0CE|rigid:c7PMZXUdiAE6cIMTeiRiWPtID/c	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96H20	uniprotkb:Q04272	intact:EBI-747719|uniprotkb:Q8IXY3|uniprotkb:Q9UN50|ensembl:ENSP00000421380	intact:EBI-28157|uniprotkb:D6VZQ1|ensemblfungi:YMR077C	psi-mi:snf8_human(display_long)|uniprotkb:ELL-associated protein of 30 kDa(gene name synonym)|uniprotkb:SNF8(gene name)|psi-mi:SNF8(display_short)|uniprotkb:EAP30(gene name synonym)|uniprotkb:ESCRT-II complex subunit VPS22(gene name synonym)	psi-mi:vps20_yeast(display_long)|uniprotkb:ASI10(gene name synonym)|uniprotkb:CHM6(gene name synonym)|uniprotkb:VPT20(gene name synonym)|uniprotkb:YM9582.02C(orf name)|uniprotkb:YMR077C(locus name)|uniprotkb:VPS20(gene name)|psi-mi:VPS20(display_short)|uniprotkb:Vacuolar protein-targeting protein 20(gene name synonym)|uniprotkb:Amino acid sensor-independent protein 10(gene name synonym)|uniprotkb:Charged multivesicular body protein 6(gene name synonym)|uniprotkb:ESCRT-III complex subunit VPS20(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553668|imex:IM-24995-3988	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009172.2|refseq:NP_001304121.1|refseq:NP_001304122.1|refseq:NP_001304123.1|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010008"(endosome membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0016247"(channel regulator activity)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043328"(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055037"(recycling endosome)|go:"GO:0061635"(regulation of protein complex stability)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071985"(multivesicular body sorting pathway)|go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:1903772"(regulation of viral budding via host ESCRT complex)|interpro:IPR016689(ESCRT-2 complex, Snf8)|interpro:IPR036388|interpro:IPR036390|interpro:IPR040608|mint:Q96H20|rcsb pdb:2ZME|rcsb pdb:3CUQ|reactome:R-HSA-917729|reactome:R-HSA-9610379|ensembl:ENSG00000159210(gene)|ensembl:ENST00000502492(transcript)|go:"GO:0000814"(ESCRT II complex)	reactome:R-SCE-1632852|refseq:NP_013794.1|sgd:S000004682|dip:DIP-1961N|reactome:R-SCE-917729|reactome:R-SCE-9668328|ensemblfungi:YMR077C(gene)|ensemblfungi:YMR077C_mRNA(transcript)|go:"GO:0000815"(ESCRT III complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005771"(multivesicular body)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0015031"(protein transport)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0070676"(intralumenal vesicle formation)|go:"GO:1904669"(ATP export)|interpro:IPR005024(Snf7)|rcsb pdb:5FVL	-	-	crc64:CDC88BC4ADA3D602	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:FyjlBpOt9okBFV8Z+g8YLUeyCm49606	rogid:K6P+RVrruRMbHsMdRoH/v0f+0Z0559292	intact-crc:687BE40913C4B025|rigid:Z6nSM53uGs9aFz1mYDvVCNl7R4w	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P38331	uniprotkb:Q96HH9	intact:EBI-21083|uniprotkb:D6VQN8|ensemblfungi:YBR242W	intact:EBI-2832937|uniprotkb:Q9H753|uniprotkb:D3DSZ3|uniprotkb:B7Z1F2|uniprotkb:B7Z3R1|uniprotkb:B7Z6D8|uniprotkb:B7Z8T2|ensembl:ENSP00000285689	psi-mi:yb92_yeast(display_long)|uniprotkb:YBR1627(orf name)|uniprotkb:YBR242W(locus name)	psi-mi:grm2b_human(display_long)|uniprotkb:GRAMD2B(gene name)|psi-mi:GRAMD2B(display_short)|uniprotkb:GRAMD3(gene name synonym)|uniprotkb:HCV NS3-transactivated protein 2(gene name synonym)|uniprotkb:NS3TP2(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553700|imex:IM-24995-3996	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009801.1|sgd:S000000446|dip:DIP-4887N|ensemblfungi:YBR242W(gene)|ensemblfungi:YBR242W_mRNA(transcript)|go:"GO:0002953"(5'-deoxynucleotidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009159"(deoxyribonucleoside monophosphate catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0050484"(GMP 5'-nucleotidase activity)|interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|interpro:IPR039356	refseq:XP_016865274.1|refseq:NP_001139791.1|refseq:NP_001139792.1|refseq:NP_001139793.1|refseq:NP_001139794.1|refseq:NP_076416.2|refseq:XP_005272120.1|ensembl:ENSG00000155324(gene)|ensembl:ENST00000285689(transcript)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0042802"(identical protein binding)|interpro:IPR004182(GRAM)|interpro:IPR011993(Pleckstrin homology-type)	-	crc64:CDE8283134B6F48F	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:YD0aYpVRCD7mMD3RTxVDksZoE1Q559292	rogid:6UkVJddV5/mHpLX/rk00jMwCA+k9606	intact-crc:3DD6600C39833B91|rigid:ss4LaWn4LwpKJo9z82Mte3KQUTQ	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96HH9	uniprotkb:P25641	intact:EBI-2832937|uniprotkb:Q9H753|uniprotkb:D3DSZ3|uniprotkb:B7Z1F2|uniprotkb:B7Z3R1|uniprotkb:B7Z6D8|uniprotkb:B7Z8T2|ensembl:ENSP00000285689	intact:EBI-375693|uniprotkb:Q8NIL6|uniprotkb:D6VR71|ensemblfungi:YCR068W	psi-mi:grm2b_human(display_long)|uniprotkb:GRAMD2B(gene name)|psi-mi:GRAMD2B(display_short)|uniprotkb:GRAMD3(gene name synonym)|uniprotkb:HCV NS3-transactivated protein 2(gene name synonym)|uniprotkb:NS3TP2(gene name synonym)	psi-mi:atg15_yeast(display_long)|uniprotkb:ATG15(gene name)|psi-mi:ATG15(display_short)|uniprotkb:AUT5(gene name synonym)|uniprotkb:CVT17(gene name synonym)|uniprotkb:YCR068W(locus name)|uniprotkb:YCR68W(orf name)|uniprotkb:Autophagy-related protein 15(gene name synonym)|uniprotkb:Cytoplasm to vacuole targeting protein 17(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553696|imex:IM-24995-3995	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_016865274.1|refseq:NP_001139791.1|refseq:NP_001139792.1|refseq:NP_001139793.1|refseq:NP_001139794.1|refseq:NP_076416.2|refseq:XP_005272120.1|ensembl:ENSG00000155324(gene)|ensembl:ENST00000285689(transcript)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0042802"(identical protein binding)|interpro:IPR004182(GRAM)|interpro:IPR011993(Pleckstrin homology-type)	ensemblfungi:YCR068W_mRNA(transcript)|go:"GO:0000425"(pexophagy)|go:"GO:0004620"(phospholipase activity)|go:"GO:0004806"(triglyceride lipase activity)|go:"GO:0005775"(vacuolar lumen)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006624"(vacuolar protein processing)|go:"GO:0006660"(phosphatidylserine catabolic process)|go:"GO:0006914"(autophagy)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0030397"(membrane disassembly)|go:"GO:0032585"(multivesicular body membrane)|go:"GO:0034496"(multivesicular body membrane disassembly)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0046461"(neutral lipid catabolic process)|interpro:IPR002921(Lipase, class 3)|interpro:IPR029058|ensemblfungi:YCR068W(gene)|refseq:NP_009994.2|sgd:S000000664|dip:DIP-5001N	-	-	crc64:B56ABAB72B999019	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:6UkVJddV5/mHpLX/rk00jMwCA+k9606	rogid:ttgDIIQIdYUuP+ME547oz2gZuEA559292	intact-crc:7DDF6E8BCE4E3FD2|rigid:O18CJOhduXKvpXhJ8XULUTU5KbU	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P32502	uniprotkb:Q96HA8	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	intact:EBI-741158|uniprotkb:B4DE68|uniprotkb:Q9NW95|ensembl:ENSP00000287387	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:ntaq1_human(display_long)|uniprotkb:NTAQ1(gene name)|psi-mi:NTAQ1(display_short)|uniprotkb:C8orf32(gene name synonym)|uniprotkb:Protein NH2-terminal glutamine deamidase(gene name synonym)|uniprotkb:WDYHV motif-containing protein 1(gene name synonym)|uniprotkb:WDYHV1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553680|imex:IM-24995-3991	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731	refseq:NP_060494.1|refseq:NP_001269953.1|ensembl:ENSG00000156795(gene)|ensembl:ENST00000287387(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0008418"(protein-N-terminal asparagine amidohydrolase activity)|interpro:IPR023128|interpro:IPR037132|interpro:IPR039733|mint:Q96HA8|rcsb pdb:3C9Q|rcsb pdb:4W79|rcsb pdb:6KGJ|go:"GO:0070773"(protein-N-terminal glutamine amidohydrolase activity)	-	crc64:A5409FAF1594854C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	rogid:RKX6ww+Z/Zw6bmOXa0r8C0mxlvc9606	intact-crc:AEF70C5898B15169|rigid:xjYCO1ebvGyeUhWxDtdeHBql7yk	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96HD9	uniprotkb:P32502	intact:EBI-3916242|ensembl:ENSP00000255082	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:acy3_human(display_long)|uniprotkb:ACY3(gene name)|psi-mi:ACY3(display_short)|uniprotkb:Aspartoacylase-2(gene name synonym)|uniprotkb:ASPA2(gene name synonym)|uniprotkb:Acylase III(gene name synonym)|uniprotkb:Aminoacylase-3(gene name synonym)|uniprotkb:Hepatitis C virus core-binding protein 1(gene name synonym)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553688|imex:IM-24995-3993	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_542389.1|ensembl:ENSG00000132744(gene)|ensembl:ENST00000255082(transcript)|go:"GO:0004046"(aminoacylase activity)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016788"(hydrolase activity, acting on ester bonds)|go:"GO:0016811"("hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides")|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR007036(Succinylglutamate desuccinylase/aspartoacylase)|interpro:IPR016708(Aspartoacylase)|mint:Q96HD9|reactome:R-HSA-5423646|go:"GO:0005829"(cytosol)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731	-	-	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:Zjs7m7GTDeoVuV1/ggtGOu1LRhM9606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:FCD03993CB9901AB|rigid:Lbvd1J6/Qa1iLlH2qOS4/t3acXI	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P39946	uniprotkb:Q96HB5	intact:EBI-12838|uniprotkb:D6W2W9|ensemblfungi:YOR269W	intact:EBI-744556|uniprotkb:B4DTU2|ensembl:ENSP00000470294|ensembl:ENSP00000474761|ensembl:ENSP00000475676|uniprotkb:A8K5Q5|uniprotkb:B4DF24|uniprotkb:F5GZU4|uniprotkb:B4DFC1	psi-mi:lis1_yeast(display_long)|uniprotkb:PAC1(gene name)|psi-mi:PAC1(display_short)|uniprotkb:nudF homolog(gene name synonym)|uniprotkb:LIS1(gene name synonym)|uniprotkb:Lissencephaly-1 homolog(gene name synonym)|uniprotkb:YOR269W(locus name)	psi-mi:cc120_human(display_long)|uniprotkb:CCDC120(gene name)|psi-mi:CCDC120(display_short)|uniprotkb:JM11(orf name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553684|imex:IM-24995-3992	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YOR269W(gene)|ensemblfungi:YOR269W_mRNA(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007097"(nuclear migration)|go:"GO:0030473"(nuclear migration along microtubule)|go:"GO:0031023"(microtubule organizing center organization)|go:"GO:0042802"(identical protein binding)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0051012"(microtubule sliding)|go:"GO:0051301"(cell division)|go:"GO:0070840"(dynein complex binding)|go:"GO:1903033"(positive regulation of microtubule plus-end binding)|go:"GO:2000574"(obsolete regulation of microtubule motor activity)|go:"GO:2000582"(obsolete positive regulation of microtubule motor activity, plus-end-directed)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR017252(Dynein regulator)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|interpro:IPR037190|rcsb pdb:5VH9|rcsb pdb:5VLJ|refseq:NP_014912.1|sgd:S000005795|mint:P39946|dip:DIP-1485N	refseq:NP_001156795.1|refseq:NP_296375.1|go:"GO:0005814"(centriole)|go:"GO:0008104"(protein localization)|go:"GO:0030426"(growth cone)|go:"GO:0034454"(microtubule anchoring at centrosome)|go:"GO:0120103"(centriolar subdistal appendage)|interpro:IPR021774|interpro:IPR039108|interpro:IPR043447|ensembl:ENSG00000147144(gene)|ensembl:ENST00000496529(transcript)|ensembl:ENST00000597275(transcript)|ensembl:ENST00000606812(transcript)|go:"GO:0005768"(endosome)|refseq:NP_001258764.1|refseq:NP_001258765.1|refseq:NP_001156793.2|refseq:NP_001156794.1	-	crc64:E667E4BA7602FB3B	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:tyU5fR5V8csklk2QqAQHt3Mmz7c559292	rogid:uBgmQJDTqECaTKOU/uQQHkWB/Nc9606	intact-crc:1F5E53C971B7C467|rigid:uN0faWdTYD57KDUYwnOtCHBY2BE	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P52870	uniprotkb:Q96HH9	intact:EBI-16410|ensemblfungi:YER087C-B|uniprotkb:D3DLZ4	intact:EBI-2832937|uniprotkb:Q9H753|uniprotkb:D3DSZ3|uniprotkb:B7Z1F2|uniprotkb:B7Z3R1|uniprotkb:B7Z6D8|uniprotkb:B7Z8T2|ensembl:ENSP00000285689	psi-mi:sc6b1_yeast(display_long)|uniprotkb:Sec61 complex subunit SBH1(gene name synonym)|uniprotkb:YER087BC(orf name)|uniprotkb:YER087C-B(locus name)|uniprotkb:SBH1(gene name)|psi-mi:SBH1(display_short)|uniprotkb:SEB1(gene name synonym)|uniprotkb:Sec61 complex subunit beta(gene name synonym)	psi-mi:grm2b_human(display_long)|uniprotkb:GRAMD2B(gene name)|psi-mi:GRAMD2B(display_short)|uniprotkb:GRAMD3(gene name synonym)|uniprotkb:HCV NS3-transactivated protein 2(gene name synonym)|uniprotkb:NS3TP2(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553692|imex:IM-24995-3994	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YER087C-B(gene)|ensemblfungi:YER087C-B_mRNA(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|interpro:IPR016482(Preprotein translocase Sec, Sec61-beta subunit, eukarya)|interpro:IPR030671|rcsb pdb:6N3Q|rcsb pdb:6ND1|rcsb pdb:7AFT|rcsb pdb:7KAH|rcsb pdb:7KAI|sgd:S000002128|rcsb pdb:7KAJ|rcsb pdb:7KAO|rcsb pdb:7KAP|rcsb pdb:7KAQ|rcsb pdb:7KAR|rcsb pdb:7KAS|rcsb pdb:7KAT|rcsb pdb:7KAU|rcsb pdb:7KB5|refseq:NP_011011.3|dip:DIP-5681N|mint:P52870	refseq:XP_016865274.1|refseq:NP_001139791.1|refseq:NP_001139792.1|refseq:NP_001139793.1|refseq:NP_001139794.1|refseq:NP_076416.2|refseq:XP_005272120.1|ensembl:ENSG00000155324(gene)|ensembl:ENST00000285689(transcript)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0042802"(identical protein binding)|interpro:IPR004182(GRAM)|interpro:IPR011993(Pleckstrin homology-type)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:9cYnDPhmMpAOdB2GV5TxikzpjI0559292	rogid:6UkVJddV5/mHpLX/rk00jMwCA+k9606	intact-crc:2B2F44787166B5E6|rigid:yvhZg8l9r++wGI/kFZEEQLd35DU	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96HR9	uniprotkb:P53845	intact:EBI-750345|uniprotkb:Q96LM0|uniprotkb:B2RE01|uniprotkb:A0A1L5BXV3|uniprotkb:D6W5Z0|ensembl:ENSP00000378861	intact:EBI-28230|uniprotkb:D6W0T0|ensemblfungi:YNL263C	psi-mi:reep6_human(display_long)|uniprotkb:Polyposis locus protein 1-like 1(gene name synonym)|uniprotkb:REEP6(gene name)|psi-mi:REEP6(display_short)|uniprotkb:C19orf32(gene name synonym)|uniprotkb:DP1L1(gene name synonym)	psi-mi:yif1_yeast(display_long)|uniprotkb:YNL263C(locus name)|uniprotkb:N0820(orf name)|uniprotkb:YIF1(gene name)|psi-mi:YIF1(display_short)|uniprotkb:YIP1-interacting factor 1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553716|imex:IM-24995-4000	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_612402.1|refseq:NP_001316485.1|ensembl:ENSG00000115255(gene)|ensembl:ENST00000395479(transcript)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030665"(clathrin-coated vesicle membrane)|go:"GO:0032386"(regulation of intracellular transport)|go:"GO:0050908"(detection of light stimulus involved in visual perception)|interpro:IPR004345(TB2/DP1 and HVA22 related protein)|mint:Q96HR9|reactome:R-HSA-381753|go:"GO:0005634"(nucleus)	refseq:NP_014136.1|sgd:S000005207|dip:DIP-1729N|ensemblfungi:YNL263C(gene)|ensemblfungi:YNL263C_mRNA(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0015031"(protein transport)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0030173"(integral component of Golgi membrane)|interpro:IPR005578(Hrf1)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2017/05/05	rogid:pB8AjjNTpmaaLJ8j7MCBM45UAHE9606	rogid:HEs4ZRFWRAkXinwmuLiWGpmUqsM559292	intact-crc:65A1DB2296558E01|rigid:NrYeqeWFOpq/h3AvUoDJC6WdpbE	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96HR9	uniprotkb:P38340	intact:EBI-750345|uniprotkb:Q96LM0|uniprotkb:B2RE01|uniprotkb:A0A1L5BXV3|uniprotkb:D6W5Z0|ensembl:ENSP00000378861	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:reep6_human(display_long)|uniprotkb:Polyposis locus protein 1-like 1(gene name synonym)|uniprotkb:REEP6(gene name)|psi-mi:REEP6(display_short)|uniprotkb:C19orf32(gene name synonym)|uniprotkb:DP1L1(gene name synonym)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553704|imex:IM-24995-3997	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_612402.1|refseq:NP_001316485.1|ensembl:ENSG00000115255(gene)|ensembl:ENST00000395479(transcript)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030665"(clathrin-coated vesicle membrane)|go:"GO:0032386"(regulation of intracellular transport)|go:"GO:0050908"(detection of light stimulus involved in visual perception)|interpro:IPR004345(TB2/DP1 and HVA22 related protein)|mint:Q96HR9|reactome:R-HSA-381753|go:"GO:0005634"(nucleus)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F	-	-	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2017/05/05	rogid:pB8AjjNTpmaaLJ8j7MCBM45UAHE9606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:0694ED5C28D41430|rigid:L17CSpZs0kLHM9zevg3Ez0Ws3s4	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96HR9	uniprotkb:P32502	intact:EBI-750345|uniprotkb:Q96LM0|uniprotkb:B2RE01|uniprotkb:A0A1L5BXV3|uniprotkb:D6W5Z0|ensembl:ENSP00000378861	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:reep6_human(display_long)|uniprotkb:Polyposis locus protein 1-like 1(gene name synonym)|uniprotkb:REEP6(gene name)|psi-mi:REEP6(display_short)|uniprotkb:C19orf32(gene name synonym)|uniprotkb:DP1L1(gene name synonym)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553708|imex:IM-24995-3998	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_612402.1|refseq:NP_001316485.1|ensembl:ENSG00000115255(gene)|ensembl:ENST00000395479(transcript)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030665"(clathrin-coated vesicle membrane)|go:"GO:0032386"(regulation of intracellular transport)|go:"GO:0050908"(detection of light stimulus involved in visual perception)|interpro:IPR004345(TB2/DP1 and HVA22 related protein)|mint:Q96HR9|reactome:R-HSA-381753|go:"GO:0005634"(nucleus)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731	-	-	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2017/05/05	rogid:pB8AjjNTpmaaLJ8j7MCBM45UAHE9606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:E267CCCD4E638FED|rigid:6hotnndLX78u2i77ARKqwuySncI	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96HR9	uniprotkb:P38815	intact:EBI-750345|uniprotkb:Q96LM0|uniprotkb:B2RE01|uniprotkb:A0A1L5BXV3|uniprotkb:D6W5Z0|ensembl:ENSP00000378861	intact:EBI-24665|uniprotkb:D3DL55|ensemblfungi:YHR105W	psi-mi:reep6_human(display_long)|uniprotkb:Polyposis locus protein 1-like 1(gene name synonym)|uniprotkb:REEP6(gene name)|psi-mi:REEP6(display_short)|uniprotkb:C19orf32(gene name synonym)|uniprotkb:DP1L1(gene name synonym)	psi-mi:ypt35_yeast(display_long)|uniprotkb:YHR105W(locus name)|uniprotkb:YPT35(gene name)|psi-mi:YPT35(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553712|imex:IM-24995-3999	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_612402.1|refseq:NP_001316485.1|ensembl:ENSG00000115255(gene)|ensembl:ENST00000395479(transcript)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030665"(clathrin-coated vesicle membrane)|go:"GO:0032386"(regulation of intracellular transport)|go:"GO:0050908"(detection of light stimulus involved in visual perception)|interpro:IPR004345(TB2/DP1 and HVA22 related protein)|mint:Q96HR9|reactome:R-HSA-381753|go:"GO:0005634"(nucleus)	refseq:NP_011973.1|sgd:S000001147|dip:DIP-1881N|ensemblfungi:YHR105W(gene)|ensemblfungi:YHR105W_mRNA(transcript)|go:"GO:0005768"(endosome)|go:"GO:0010008"(endosome membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|interpro:IPR001683(Phox-like)|interpro:IPR036871|interpro:IPR037917	-	-	crc64:2ADD21AF107094DC	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2017/05/05	rogid:pB8AjjNTpmaaLJ8j7MCBM45UAHE9606	rogid:fUTJG8BaTveH3zB/0W1vNh4BU2Y559292	intact-crc:46F97988FCE21596|rigid:c9CbZDzhbB3Kso14dHqlrn66Jag	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96IK5	uniprotkb:P21651	intact:EBI-2548508|ensembl:ENSP00000282570|uniprotkb:Q9H826|uniprotkb:Q9H8V7|uniprotkb:Q9H927	intact:EBI-10742|ensemblfungi:YJR021C|uniprotkb:D6VWJ5	psi-mi:gmcl1_human(display_long)|uniprotkb:GMCL1(gene name)|psi-mi:GMCL1(display_short)|uniprotkb:GCL(gene name synonym)|uniprotkb:BTBD13(gene name synonym)|uniprotkb:SPATA29(gene name synonym)|uniprotkb:Spermatogenesis-associated protein 29(gene name synonym)	psi-mi:re107_yeast(display_long)|uniprotkb:MER2(gene name synonym)|uniprotkb:J1462(orf name)|uniprotkb:YJR021C(locus name)|uniprotkb:REC107(gene name)|psi-mi:REC107(display_short)|uniprotkb:Meiotic recombination protein 2(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553740|imex:IM-24995-4006	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000087338(gene)|ensembl:ENST00000282570(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0007281"(germ cell development)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016363"(nuclear matrix)|go:"GO:0042802"(identical protein binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR043380|refseq:NP_848526.1	ensemblfungi:YJR021C(gene)|ensemblfungi:YJR021C_mRNA(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0042802"(identical protein binding)|interpro:IPR015159(Mer2)|sgd:S000003782|refseq:NP_012555.1|dip:DIP-5265N	-	-	crc64:46F426AC0DFDFAD0	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:ED8yqySVu7BWxpw3DUSNBZSQWrk9606	rogid:v9kR3rBIptwb/cZE7B5IMAkYWKc559292	intact-crc:313460A6C3021EF3|rigid:bOFaBcDqb6RObTx/Mdo/KzneuAU	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96IK5	uniprotkb:P20459	intact:EBI-2548508|ensembl:ENSP00000282570|uniprotkb:Q9H826|uniprotkb:Q9H8V7|uniprotkb:Q9H927	intact:EBI-8915|uniprotkb:E9P8T6|ensemblfungi:YJR007W|uniprotkb:D6VWI2	psi-mi:gmcl1_human(display_long)|uniprotkb:GMCL1(gene name)|psi-mi:GMCL1(display_short)|uniprotkb:GCL(gene name synonym)|uniprotkb:BTBD13(gene name synonym)|uniprotkb:SPATA29(gene name synonym)|uniprotkb:Spermatogenesis-associated protein 29(gene name synonym)	psi-mi:if2a_yeast(display_long)|uniprotkb:SUI2(gene name)|psi-mi:SUI2(display_short)|uniprotkb:TIF211(gene name synonym)|uniprotkb:YJR007W(locus name)|uniprotkb:J1429(orf name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553736|imex:IM-24995-4005	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000087338(gene)|ensembl:ENST00000282570(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0007281"(germ cell development)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016363"(nuclear matrix)|go:"GO:0042802"(identical protein binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR043380|refseq:NP_848526.1	interpro:IPR022967|interpro:IPR024054|interpro:IPR024055|interpro:IPR044126|rcsb pdb:1Q46|rcsb pdb:2A19|rcsb pdb:2A1A|rcsb pdb:3J81|rcsb pdb:3JAP|rcsb pdb:3JAQ|rcsb pdb:6FYX|rcsb pdb:6FYY|rcsb pdb:6GSM|rcsb pdb:6GSN|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6JLY|rcsb pdb:6JLZ|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-156827|reactome:R-SCE-381042|reactome:R-SCE-72649|reactome:R-SCE-72695|reactome:R-SCE-72702|reactome:R-SCE-72731|ensemblfungi:YJR007W(gene)|ensemblfungi:YJR007W_mRNA(transcript)|go:"GO:0001731"(formation of translation preinitiation complex)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005850"(eukaryotic translation initiation factor 2 complex)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0043022"(ribosome binding)|go:"GO:0043614"(multi-eIF complex)|interpro:IPR003029(S1, RNA binding)|interpro:IPR011488(Eukaryotic translation initiation factor 2, alpha subunit)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|refseq:NP_012540.3|sgd:S000003767|mint:P20459|dip:DIP-2327N	-	-	crc64:AF4F1C80303A4E98	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:ED8yqySVu7BWxpw3DUSNBZSQWrk9606	rogid:9/iGImP9/c8HSYwgmItME27z7lE559292	intact-crc:6DCC7EB6C4E9C27F|rigid:IoMb+WSQ/W6Elnkz1GDET4tvspo	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O14468	uniprotkb:Q96HT8	intact:EBI-2343965|uniprotkb:D6W304|ensemblfungi:YOR304C-A	intact:EBI-748896|uniprotkb:Q6NXT8|uniprotkb:Q9P0J5|uniprotkb:B2R6R0|ensembl:ENSP00000318154	psi-mi:yo304_yeast(display_long)|uniprotkb:YOR304C-A(locus name)	psi-mi:mr1l1_human(display_long)|uniprotkb:PP784(orf name)|uniprotkb:MRFAP1L1(gene name)|psi-mi:MRFAP1L1(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553720|imex:IM-24995-4001	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005830|refseq:NP_014949.3|mint:O14468|ensemblfungi:YOR304C-A(gene)|ensemblfungi:YOR304C-A_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005933"(cellular bud)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0043332"(mating projection tip)|go:"GO:0051017"(actin filament bundle assembly)	refseq:NP_982287.1|refseq:XP_005247989.1|ensembl:ENSG00000178988(gene)|ensembl:ENST00000320848(transcript)|go:"GO:0042802"(identical protein binding)|interpro:IPR029254|mint:Q96HT8|dip:DIP-29019N	-	-	caution:This sequence has been withdrawn from Uniprot.|crc64:6C914B0B4BEECAE5	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:+5KU/P9FeqlhSbGhpYJ1V6DqQNg559292	rogid:hb4enqSS7DeieOByDoLDkXkSlIk9606	intact-crc:3770AC26E67EBD5D|rigid:vkfqnxFf5tR9GxUo1dAyIRUfIB0	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P25637	uniprotkb:Q96HT8	intact:EBI-21951|uniprotkb:D6VR64|ensemblfungi:YCR059C	intact:EBI-748896|uniprotkb:Q6NXT8|uniprotkb:Q9P0J5|uniprotkb:B2R6R0|ensembl:ENSP00000318154	psi-mi:yih1_yeast(display_long)|uniprotkb:YCR59C(orf name)|uniprotkb:YCR059C(locus name)|uniprotkb:YIH1(gene name)|psi-mi:YIH1(display_short)	psi-mi:mr1l1_human(display_long)|uniprotkb:PP784(orf name)|uniprotkb:MRFAP1L1(gene name)|psi-mi:MRFAP1L1(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553728|imex:IM-24995-4003	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009985.1|sgd:S000000655|mint:P25637|dip:DIP-1846N|ensemblfungi:YCR059C(gene)|ensemblfungi:YCR059C_mRNA(transcript)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0003785"(actin monomer binding)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0033673"(negative regulation of kinase activity)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0043022"(ribosome binding)|go:"GO:0140469"(GCN2-mediated signaling)|go:"GO:1905538"(polysome binding)|interpro:IPR001498(Protein of unknown function UPF0029, N-terminal)|interpro:IPR006575(RWD)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR020568|interpro:IPR020569|interpro:IPR023582|interpro:IPR036956|rcsb pdb:6BQI|rcsb pdb:6U1L|rcsb pdb:6U1O	refseq:NP_982287.1|refseq:XP_005247989.1|ensembl:ENSG00000178988(gene)|ensembl:ENST00000320848(transcript)|go:"GO:0042802"(identical protein binding)|interpro:IPR029254|mint:Q96HT8|dip:DIP-29019N	-	-	caution:This sequence has been withdrawn from Uniprot.|crc64:6C914B0B4BEECAE5	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:aAbGir3o4M0LUpwOv6YBC25KpQQ559292	rogid:hb4enqSS7DeieOByDoLDkXkSlIk9606	intact-crc:14AA6FDF4D6374B6|rigid:DmLeJugk9z8HWbVTC4xBweyUnV0	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P32902	uniprotkb:Q96HT8	intact:EBI-16248|ensemblfungi:YHL004W|uniprotkb:D3DKR0	intact:EBI-748896|uniprotkb:Q6NXT8|uniprotkb:Q9P0J5|uniprotkb:B2R6R0|ensembl:ENSP00000318154	psi-mi:rt04_yeast(display_long)|uniprotkb:MRP4(gene name)|psi-mi:MRP4(display_short)|uniprotkb:MRP4A(gene name synonym)|uniprotkb:Mitochondrial small ribosomal subunit protein uS2m(gene name synonym)|uniprotkb:YHL004W(locus name)	psi-mi:mr1l1_human(display_long)|uniprotkb:PP784(orf name)|uniprotkb:MRFAP1L1(gene name)|psi-mi:MRFAP1L1(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553724|imex:IM-24995-4002	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YHL004W(gene)|ensemblfungi:YHL004W_mRNA(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR001865(Ribosomal protein S2)|interpro:IPR005706(Ribosomal protein S2, bacterial-type)|interpro:IPR018130|interpro:IPR023591|rcsb pdb:5MRC|rcsb pdb:5MRE|rcsb pdb:5MRF|refseq:NP_011859.1|sgd:S000000996|dip:DIP-5035N|mint:P32902	refseq:NP_982287.1|refseq:XP_005247989.1|ensembl:ENSG00000178988(gene)|ensembl:ENST00000320848(transcript)|go:"GO:0042802"(identical protein binding)|interpro:IPR029254|mint:Q96HT8|dip:DIP-29019N	-	crc64:81A1CB33134BC559	caution:This sequence has been withdrawn from Uniprot.|crc64:6C914B0B4BEECAE5	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:BlL3W6HUN+uAKF/AxwlV1zT5YZQ559292	rogid:hb4enqSS7DeieOByDoLDkXkSlIk9606	intact-crc:247CD87C93554BE3|rigid:BDBlsC/ZZCeS2HYGVz/rgdVL+1Y	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96HU1	uniprotkb:P38913	intact:EBI-7362971|uniprotkb:B0QY79|intact:UNK-5498582|uniprotkb:Q7Z709|uniprotkb:Q9NT69|ensembl:ENSP00000248929	intact:EBI-6763|ensemblfungi:YDL045C|uniprotkb:D6VRV1	psi-mi:sgsm3_human(display_long)|uniprotkb:SGSM3(gene name)|psi-mi:SGSM3(display_short)|uniprotkb:MAP(gene name synonym)|uniprotkb:RABGAPLP(gene name synonym)|uniprotkb:RUTBC3(gene name synonym)|uniprotkb:RUN and TBC1 domain-containing protein 3(gene name synonym)|uniprotkb:Rab-GTPase-activating protein-like protein(gene name synonym)|uniprotkb:Merlin-associated protein(gene name synonym)	psi-mi:fad1_yeast(display_long)|uniprotkb:FAD1(gene name)|psi-mi:FAD1(display_short)|uniprotkb:FMN adenylyltransferase(gene name synonym)|uniprotkb:D2702(orf name)|uniprotkb:YDL045C(locus name)|uniprotkb:FAD pyrophosphorylase(gene name synonym)|uniprotkb:Flavin adenine dinucleotide synthase(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553732|imex:IM-24995-4004	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001288778.1|refseq:NP_056520.2|ensembl:ENSG00000100359(gene)|ensembl:ENST00000248929(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005829"(cytosol)|go:"GO:0005921"(gap junction)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007049"(cell cycle)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032483"(regulation of Rab protein signal transduction)|go:"GO:0032486"(Rap protein signal transduction)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0048227"(plasma membrane to endosome transport)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR001452(Src homology-3)|interpro:IPR004012(RUN)|interpro:IPR035833|interpro:IPR035969|interpro:IPR036028|interpro:IPR037213	refseq:NP_010239.1|sgd:S000002203|ensemblfungi:YDL045C(gene)|ensemblfungi:YDL045C_mRNA(transcript)|go:"GO:0003919"(FMN adenylyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006747"(FAD biosynthetic process)|interpro:IPR002500(Phosphoadenosine phosphosulphate reductase)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|rcsb pdb:2WSI|reactome:R-SCE-196843|dip:DIP-4735N	-	function:May play a cooperative role in NF2-mediated growth suppression of cells|comment:mint|comment:homomint	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:9V+BpqGXordWG7hcdP/l6QL4+Lg9606	rogid:fdv5ldkxx7ZxwNTBS+oAAbwPkOc559292	intact-crc:FB59C2FAF1520AAD|rigid:MBbbXEOtPz5tgr0lhq0U/cqNHgA	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
intact:EBI-11522371	uniprotkb:Q96IK5	-	intact:EBI-2548508|ensembl:ENSP00000282570|uniprotkb:Q9H826|uniprotkb:Q9H8V7|uniprotkb:Q9H927	psi-mi:yjr003c(display_short)|psi-mi:EBI-11522371(display_long)	psi-mi:gmcl1_human(display_long)|uniprotkb:GMCL1(gene name)|psi-mi:GMCL1(display_short)|uniprotkb:GCL(gene name synonym)|uniprotkb:BTBD13(gene name synonym)|uniprotkb:SPATA29(gene name synonym)|uniprotkb:Spermatogenesis-associated protein 29(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553744|imex:IM-24995-4007	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSG00000087338(gene)|ensembl:ENST00000282570(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0007281"(germ cell development)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016363"(nuclear matrix)|go:"GO:0042802"(identical protein binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR043380|refseq:NP_848526.1	-	no-uniprot-update:	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:dYGrrP3JnrXO2rj4v/nTT64la6A4932	rogid:ED8yqySVu7BWxpw3DUSNBZSQWrk9606	intact-crc:4F940A34BC9BFFD9|rigid:dbccop0gcphLz75QVz1aGzwaVvg	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96IK5	uniprotkb:P38986	intact:EBI-2548508|ensembl:ENSP00000282570|uniprotkb:Q9H826|uniprotkb:Q9H8V7|uniprotkb:Q9H927	intact:EBI-3014|uniprotkb:D6VSV3|ensemblfungi:YDR321W	psi-mi:gmcl1_human(display_long)|uniprotkb:GMCL1(gene name)|psi-mi:GMCL1(display_short)|uniprotkb:GCL(gene name synonym)|uniprotkb:BTBD13(gene name synonym)|uniprotkb:SPATA29(gene name synonym)|uniprotkb:Spermatogenesis-associated protein 29(gene name synonym)	psi-mi:aspg1_yeast(display_long)|uniprotkb:YDR321W(locus name)|uniprotkb:D9798.6(orf name)|uniprotkb:ASP1(gene name)|psi-mi:ASP1(display_short)|uniprotkb:L-asparaginase I(gene name synonym)|uniprotkb:L-asparagine amidohydrolase I(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553756|imex:IM-24995-4010	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000087338(gene)|ensembl:ENST00000282570(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0007281"(germ cell development)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016363"(nuclear matrix)|go:"GO:0042802"(identical protein binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR043380|refseq:NP_848526.1	sgd:S000002729|refseq:NP_010607.3|dip:DIP-4030N|mint:P38986|ensemblfungi:YDR321W(gene)|ensemblfungi:YDR321W_mRNA(transcript)|go:"GO:0004067"(asparaginase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006530"(asparagine catabolic process)|go:"GO:0042597"(periplasmic space)|interpro:IPR004550(L-asparaginase, type II)|interpro:IPR006034(Asparaginase/glutaminase)|interpro:IPR020827|interpro:IPR027473|interpro:IPR027474|interpro:IPR027475|interpro:IPR036152|interpro:IPR037152|interpro:IPR040919	-	-	crc64:8204CB7C58B5B75F	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:ED8yqySVu7BWxpw3DUSNBZSQWrk9606	rogid:vIy3riBmCKfYQjsh3cIcO7o1Bzw559292	intact-crc:0DF82D00EDDDB826|rigid:oy943M8+iFCiGMpW9GCtR8GGXvI	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96IK5	uniprotkb:Q12259	intact:EBI-2548508|ensembl:ENSP00000282570|uniprotkb:Q9H826|uniprotkb:Q9H8V7|uniprotkb:Q9H927	intact:EBI-30776|uniprotkb:D6VYA8|ensemblfungi:YLR108C	psi-mi:gmcl1_human(display_long)|uniprotkb:GMCL1(gene name)|psi-mi:GMCL1(display_short)|uniprotkb:GCL(gene name synonym)|uniprotkb:BTBD13(gene name synonym)|uniprotkb:SPATA29(gene name synonym)|uniprotkb:Spermatogenesis-associated protein 29(gene name synonym)	psi-mi:yl108_yeast(display_long)|uniprotkb:L2913(orf name)|uniprotkb:YLR108C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553752|imex:IM-24995-4009	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000087338(gene)|ensembl:ENST00000282570(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0007281"(germ cell development)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016363"(nuclear matrix)|go:"GO:0042802"(identical protein binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR043380|refseq:NP_848526.1	refseq:NP_013209.1|sgd:S000004098|dip:DIP-4075N|ensemblfungi:YLR108C(gene)|ensemblfungi:YLR108C_mRNA(transcript)|go:"GO:0005634"(nucleus)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:ED8yqySVu7BWxpw3DUSNBZSQWrk9606	rogid:CzknxXhhvgMp3J0/oi197EgZ05U559292	intact-crc:613A9B2A3FA71AE5|rigid:gCLE2yb9pKKf3IwPtUB5pCdLuxk	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96IK5	uniprotkb:P40507	intact:EBI-2548508|ensembl:ENSP00000282570|uniprotkb:Q9H826|uniprotkb:Q9H8V7|uniprotkb:Q9H927	intact:EBI-25083|uniprotkb:D6VVK5|ensemblfungi:YIL079C	psi-mi:gmcl1_human(display_long)|uniprotkb:GMCL1(gene name)|psi-mi:GMCL1(display_short)|uniprotkb:GCL(gene name synonym)|uniprotkb:BTBD13(gene name synonym)|uniprotkb:SPATA29(gene name synonym)|uniprotkb:Spermatogenesis-associated protein 29(gene name synonym)	psi-mi:air1_yeast(display_long)|uniprotkb:Arginine methyltransferase-interacting RING finger protein 1(gene name synonym)|uniprotkb:AIR1(gene name)|psi-mi:AIR1(display_short)|uniprotkb:YIL079C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553748|imex:IM-24995-4008	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000087338(gene)|ensembl:ENST00000282570(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0007281"(germ cell development)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016363"(nuclear matrix)|go:"GO:0042802"(identical protein binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR043380|refseq:NP_848526.1	refseq:NP_012186.1|sgd:S000001341|mint:P40507|dip:DIP-2700N|ensemblfungi:YIL079C(gene)|ensemblfungi:YIL079C_mRNA(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031499"(TRAMP complex)|go:"GO:0043629"(ncRNA polyadenylation)|go:"GO:0071031"(nuclear mRNA surveillance of mRNA 3'-end processing)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071036"(nuclear polyadenylation-dependent snoRNA catabolic process)|go:"GO:0071037"(nuclear polyadenylation-dependent snRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071039"(nuclear polyadenylation-dependent CUT catabolic process)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR016713("Poly(A) polymerase complex, Air1/2")|interpro:IPR036875	-	-	crc64:3CA920FA1204EC9C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:ED8yqySVu7BWxpw3DUSNBZSQWrk9606	rogid:myPxXwP+mJgvoh50PLYk2Q3GMh4559292	intact-crc:0D8ECDB2073DBF18|rigid:vdWOOQGg2EmQkl9dneCG+ZkcJBk	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96KN7-4	uniprotkb:P32902	intact:EBI-11525164|ensembl:ENSP00000372391	intact:EBI-16248|ensemblfungi:YHL004W|uniprotkb:D3DKR0	psi-mi:q96kn7-4(display_long)|uniprotkb:RPGRIP1(gene name)|psi-mi:RPGRIP1(display_short)	psi-mi:rt04_yeast(display_long)|uniprotkb:MRP4(gene name)|psi-mi:MRP4(display_short)|uniprotkb:MRP4A(gene name synonym)|uniprotkb:Mitochondrial small ribosomal subunit protein uS2m(gene name synonym)|uniprotkb:YHL004W(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553784|imex:IM-24995-4017	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-1050213(isoform-parent)|ensembl:ENSG00000092200(gene)|ensembl:ENST00000382933(transcript)|uniprotkb:Q96KN7-4(isoform-parent)	ensemblfungi:YHL004W(gene)|ensemblfungi:YHL004W_mRNA(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR001865(Ribosomal protein S2)|interpro:IPR005706(Ribosomal protein S2, bacterial-type)|interpro:IPR018130|interpro:IPR023591|rcsb pdb:5MRC|rcsb pdb:5MRE|rcsb pdb:5MRF|refseq:NP_011859.1|sgd:S000000996|dip:DIP-5035N|mint:P32902	-	-	crc64:81A1CB33134BC559	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Xy0433uM/nWhWLM/EsfESPJDIy49606	rogid:BlL3W6HUN+uAKF/AxwlV1zT5YZQ559292	intact-crc:8916F47704A6F456|rigid:XlxHB0UGXHGaHmIOBTNAOgoMUEc	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96KN7-4	uniprotkb:P39518	intact:EBI-11525164|ensembl:ENSP00000372391	intact:EBI-10082|uniprotkb:D3DLR3|ensemblfungi:YER015W	psi-mi:q96kn7-4(display_long)|uniprotkb:RPGRIP1(gene name)|psi-mi:RPGRIP1(display_short)	psi-mi:lcf2_yeast(display_long)|uniprotkb:YER015W(locus name)|uniprotkb:FAA2(gene name)|psi-mi:FAA2(display_short)|uniprotkb:FAM1(gene name synonym)|uniprotkb:Long-chain acyl-CoA synthetase 2(gene name synonym)|uniprotkb:Fatty acid activator 2(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553776|imex:IM-24995-4015	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-1050213(isoform-parent)|ensembl:ENSG00000092200(gene)|ensembl:ENST00000382933(transcript)|uniprotkb:Q96KN7-4(isoform-parent)	sgd:S000000817|ensemblfungi:YER015W_mRNA(transcript)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0004467"(long-chain fatty acid-CoA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0015910"(long-chain fatty acid import into peroxisome)|go:"GO:0015916"(fatty-acyl-CoA transport)|go:"GO:0016020"(membrane)|go:"GO:0031956"(medium-chain fatty acid-CoA ligase activity)|go:"GO:0031957"(very long-chain fatty acid-CoA ligase activity)|go:"GO:0042760"(very long-chain fatty acid catabolic process)|go:"GO:0102391"(decanoate-CoA ligase activity)|ensemblfungi:YER015W(gene)|interpro:IPR020845|interpro:IPR000873(AMP-dependent synthetase and ligase)|reactome:R-SCE-75876|refseq:NP_010931.3|dip:DIP-6565N	-	-	crc64:1E023C18682805BC	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Xy0433uM/nWhWLM/EsfESPJDIy49606	rogid:N0W+wPvCsl01y0k8hJZ156LztOo559292	intact-crc:765A9725D719E8F4|rigid:/6AjyN53VR+VGsZRy2aKUCAVJLw	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P53829	uniprotkb:Q96IK5	intact:EBI-28306|uniprotkb:D6W0Q5|ensemblfungi:YNL288W	intact:EBI-2548508|ensembl:ENSP00000282570|uniprotkb:Q9H826|uniprotkb:Q9H8V7|uniprotkb:Q9H927	psi-mi:caf40_yeast(display_long)|uniprotkb:YNL288W(locus name)|uniprotkb:N0540(orf name)|uniprotkb:40 kDa CCR4-associated factor(gene name synonym)|uniprotkb:CAF40(gene name)|psi-mi:CAF40(display_short)	psi-mi:gmcl1_human(display_long)|uniprotkb:GMCL1(gene name)|psi-mi:GMCL1(display_short)|uniprotkb:GCL(gene name synonym)|uniprotkb:BTBD13(gene name synonym)|uniprotkb:SPATA29(gene name synonym)|uniprotkb:Spermatogenesis-associated protein 29(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553768|imex:IM-24995-4013	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014111.1|sgd:S000005232|dip:DIP-1995N|mint:P53829|ensemblfungi:YNL288W(gene)|ensemblfungi:YNL288W_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR007216(Cell differentiation, Rcd1-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:4CV5	ensembl:ENSG00000087338(gene)|ensembl:ENST00000282570(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0007281"(germ cell development)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016363"(nuclear matrix)|go:"GO:0042802"(identical protein binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR043380|refseq:NP_848526.1	-	crc64:F3DBABE6AD3C7F3C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:etuSSgFGQOcgxPDexEXUqQg6H5s559292	rogid:ED8yqySVu7BWxpw3DUSNBZSQWrk9606	intact-crc:8A1493CA8F1D4150|rigid:9+9FWWtCkFBRiYY6flmnSQGpyz4	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96IK5	uniprotkb:P10507	intact:EBI-2548508|ensembl:ENSP00000282570|uniprotkb:Q9H826|uniprotkb:Q9H8V7|uniprotkb:Q9H927	intact:EBI-11212|uniprotkb:D6VYG9|ensemblfungi:YLR163C	psi-mi:gmcl1_human(display_long)|uniprotkb:GMCL1(gene name)|psi-mi:GMCL1(display_short)|uniprotkb:GCL(gene name synonym)|uniprotkb:BTBD13(gene name synonym)|uniprotkb:SPATA29(gene name synonym)|uniprotkb:Spermatogenesis-associated protein 29(gene name synonym)	psi-mi:mppb_yeast(display_long)|uniprotkb:MAS1(gene name)|psi-mi:MAS1(display_short)|uniprotkb:MIF1(gene name synonym)|uniprotkb:Beta-MPP(gene name synonym)|uniprotkb:Mitochondrial assembly protein 1(gene name synonym)|uniprotkb:Processing enhancing protein(gene name synonym)|uniprotkb:L9632.10(orf name)|uniprotkb:YLR163C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553764|imex:IM-24995-4012	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000087338(gene)|ensembl:ENST00000282570(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0007281"(germ cell development)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016363"(nuclear matrix)|go:"GO:0042802"(identical protein binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR043380|refseq:NP_848526.1	rcsb pdb:1HR8|rcsb pdb:1HR9|reactome:R-SCE-611105|ensemblfungi:YLR163C_mRNA(transcript)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006627"(protein processing involved in protein targeting to mitochondrion)|go:"GO:0017087"(mitochondrial processing peptidase complex)|go:"GO:0046872"(metal ion binding)|interpro:IPR001431(Peptidase M16, zinc-binding site)|interpro:IPR007863(Peptidase M16, C-terminal)|interpro:IPR011249(Metalloenzyme, LuxS/M16 peptidase-like, metal-binding)|interpro:IPR011765(Peptidase M16, N-terminal)|rcsb pdb:1HR6|rcsb pdb:1HR7|ensemblfungi:YLR163C(gene)|refseq:NP_013264.1|sgd:S000004153|mint:P10507|dip:DIP-2402N	-	-	crc64:084CE63C495EDFC4	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:ED8yqySVu7BWxpw3DUSNBZSQWrk9606	rogid:VwOYuBlWEvXC631d5WAhOhjVAPc559292	intact-crc:4D73BE68B5352990|rigid:kUmOXYm7g25dCm8NYfT0YIStVMA	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P53202	uniprotkb:Q96IK5	intact:EBI-23065|uniprotkb:D6VUE0|ensemblfungi:YGR003W	intact:EBI-2548508|ensembl:ENSP00000282570|uniprotkb:Q9H826|uniprotkb:Q9H8V7|uniprotkb:Q9H927	psi-mi:cul3_yeast(display_long)|uniprotkb:CUL3(gene name)|psi-mi:CUL3(display_short)|uniprotkb:Cullin-B(gene name synonym)|uniprotkb:YGR003W(locus name)	psi-mi:gmcl1_human(display_long)|uniprotkb:GMCL1(gene name)|psi-mi:GMCL1(display_short)|uniprotkb:GCL(gene name synonym)|uniprotkb:BTBD13(gene name synonym)|uniprotkb:SPATA29(gene name synonym)|uniprotkb:Spermatogenesis-associated protein 29(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553760|imex:IM-24995-4011	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011517.1|sgd:S000003235|dip:DIP-5506N|mint:P53202|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|ensemblfungi:YGR003W(gene)|ensemblfungi:YGR003W_mRNA(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)	ensembl:ENSG00000087338(gene)|ensembl:ENST00000282570(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0007281"(germ cell development)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016363"(nuclear matrix)|go:"GO:0042802"(identical protein binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR043380|refseq:NP_848526.1	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:FvYjEpmLA9mF35UTi97nLZwp0eE559292	rogid:ED8yqySVu7BWxpw3DUSNBZSQWrk9606	intact-crc:19486C7D89E92C21|rigid:kjnuALvK/s4J4YRNLcNbpMJrLbA	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96KN7-4	uniprotkb:P29461	intact:EBI-11525164|ensembl:ENSP00000372391	intact:EBI-14188|ensemblfungi:YOR208W|uniprotkb:D6W2R4	psi-mi:q96kn7-4(display_long)|uniprotkb:RPGRIP1(gene name)|psi-mi:RPGRIP1(display_short)	psi-mi:ptp2_yeast(display_long)|uniprotkb:Protein-tyrosine phosphatase 2(gene name synonym)|uniprotkb:PTP2(gene name)|psi-mi:PTP2(display_short)|uniprotkb:YOR208W(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553780|imex:IM-24995-4016	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-1050213(isoform-parent)|ensembl:ENSG00000092200(gene)|ensembl:ENST00000382933(transcript)|uniprotkb:Q96KN7-4(isoform-parent)	sgd:S000005734|ensemblfungi:YOR208W(gene)|ensemblfungi:YOR208W_mRNA(transcript)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0043937"(regulation of sporulation)|go:"GO:0051457"(maintenance of protein location in nucleus)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|refseq:NP_014851.3|dip:DIP-2369N	-	-	crc64:1033D2F0AA23BD35	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Xy0433uM/nWhWLM/EsfESPJDIy49606	rogid:y6lL7sE5o4uuIJ2YtaKCUzxz8o0559292	intact-crc:EDAC653F1D007AF7|rigid:sWHPGmW1pLVHtqfUvOASr//pG4M	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q07732	uniprotkb:Q96IK5	intact:EBI-33406|ensemblfungi:YDL239C|uniprotkb:D6VRB7	intact:EBI-2548508|ensembl:ENSP00000282570|uniprotkb:Q9H826|uniprotkb:Q9H8V7|uniprotkb:Q9H927	psi-mi:ady3_yeast(display_long)|uniprotkb:YDL239C(locus name)|uniprotkb:ADY3(gene name)|psi-mi:ADY3(display_short)	psi-mi:gmcl1_human(display_long)|uniprotkb:GMCL1(gene name)|psi-mi:GMCL1(display_short)|uniprotkb:GCL(gene name synonym)|uniprotkb:BTBD13(gene name synonym)|uniprotkb:SPATA29(gene name synonym)|uniprotkb:Spermatogenesis-associated protein 29(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553772|imex:IM-24995-4014	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010042.2|sgd:S000002398|ensemblfungi:YDL239C(gene)|ensemblfungi:YDL239C_mRNA(transcript)|go:"GO:0000001"(mitochondrion inheritance)|go:"GO:0005628"(prospore membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0030435"(sporulation resulting in formation of a cellular spore)|go:"GO:0030476"(ascospore wall assembly)|go:"GO:0032120"(ascospore-type prospore membrane formation)|go:"GO:0051301"(cell division)|go:"GO:0070056"(prospore membrane leading edge)|interpro:IPR021750|mint:Q07732|dip:DIP-1811N	ensembl:ENSG00000087338(gene)|ensembl:ENST00000282570(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0007281"(germ cell development)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016363"(nuclear matrix)|go:"GO:0042802"(identical protein binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR043380|refseq:NP_848526.1	-	crc64:46F17474F30FD3D9	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Cmac2NLDdbBzVKnJfFricfeeX24559292	rogid:ED8yqySVu7BWxpw3DUSNBZSQWrk9606	intact-crc:B035E00327EAC475|rigid:tPzkqD4O/YtqXvlondCuqaUq5Yk	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96L14	uniprotkb:P36108	intact:EBI-743488	intact:EBI-26574|uniprotkb:D6VXT5|ensemblfungi:YKL002W	psi-mi:c170l_human(display_long)|uniprotkb:KIAA0470L(gene name synonym)|uniprotkb:CEP170P1(gene name)|psi-mi:CEP170P1(display_short)|uniprotkb:CEP170L(gene name synonym)|uniprotkb:CEP170 pseudogene 1(gene name synonym)	psi-mi:did4_yeast(display_long)|uniprotkb:VPL2(gene name synonym)|uniprotkb:VPS2(gene name synonym)|uniprotkb:VPT14(gene name synonym)|uniprotkb:YKL002W(locus name)|uniprotkb:DID4(gene name)|psi-mi:DID4(display_short)|uniprotkb:CHM2(gene name synonym)|uniprotkb:GRD7(gene name synonym)|uniprotkb:REN1(gene name synonym)|uniprotkb:Vacuolar protein-sorting-associated protein 2(gene name synonym)|uniprotkb:Vacuolar protein-targeting protein 14(gene name synonym)|uniprotkb:ESCRT-III complex subunit VPS2(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553796|imex:IM-24995-4020	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR026644|interpro:IPR029300|go:"GO:0042802"(identical protein binding)	refseq:NP_012924.2|sgd:S000001485|mint:P36108|dip:DIP-1916N|ensemblfungi:YKL002W(gene)|ensemblfungi:YKL002W_mRNA(transcript)|go:"GO:0000815"(ESCRT III complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005771"(multivesicular body)|go:"GO:0015031"(protein transport)|go:"GO:0032509"(endosome transport via multivesicular body sorting pathway)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0045053"(protein retention in Golgi apparatus)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0070676"(intralumenal vesicle formation)|go:"GO:1904669"(ATP export)|interpro:IPR005024(Snf7)|rcsb pdb:2V6X|rcsb pdb:6AP1|rcsb pdb:6BMF|reactome:R-SCE-1632852|reactome:R-SCE-917729|reactome:R-SCE-9668328	-	-	crc64:200D07DB4C45DCBC	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:Z/Rium0Kwj3ZUHa4WE5PPksPXdg9606	rogid:iQ8lcGhal3Pt46dwcOkIW2fp/G0559292	intact-crc:381DC0586A3CBBDD|rigid:RYPdLnjN5ZPY/1MSObzNeUAzgKo	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96KN7-4	uniprotkb:P38781	intact:EBI-11525164|ensembl:ENSP00000372391	intact:EBI-24549|uniprotkb:D3DL05|ensemblfungi:YHR056C	psi-mi:q96kn7-4(display_long)|uniprotkb:RPGRIP1(gene name)|psi-mi:RPGRIP1(display_short)	psi-mi:rsc30_yeast(display_long)|uniprotkb:RSC30(gene name)|psi-mi:RSC30(display_short)|uniprotkb:Remodel the structure of chromatin complex subunit 30(gene name synonym)|uniprotkb:YHR056C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553788|imex:IM-24995-4018	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-1050213(isoform-parent)|ensembl:ENSG00000092200(gene)|ensembl:ENST00000382933(transcript)|uniprotkb:Q96KN7-4(isoform-parent)	refseq:NP_011923.2|sgd:S000001098|dip:DIP-4275N|ensemblfungi:YHR056C(gene)|ensemblfungi:YHR056C_mRNA(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006337"(nucleosome disassembly)|rcsb pdb:6KW4|rcsb pdb:6KW5|rcsb pdb:6V8O|rcsb pdb:6V92|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016586"(RSC-type complex)|interpro:IPR001138(Fungal transcriptional regulatory protein, N-terminal)|interpro:IPR036864|rcsb pdb:6K15|rcsb pdb:6KW3	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:Xy0433uM/nWhWLM/EsfESPJDIy49606	rogid:NzGOxIaNyDat2EcQdWPobugunh0559292	intact-crc:ADBACBB573251D10|rigid:+lhorYUPJWwM4GE9f+q87nqe1Iw	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P46948	uniprotkb:Q96L14	intact:EBI-1788|uniprotkb:D6VUX7|ensemblfungi:YGR195W	intact:EBI-743488	psi-mi:rrp41_yeast(display_long)|uniprotkb:SKI6(gene name)|psi-mi:SKI6(display_short)|uniprotkb:YGR195W(locus name)|uniprotkb:G7587(orf name)|uniprotkb:ECM20(gene name synonym)|uniprotkb:Ribosomal RNA-processing protein 41(gene name synonym)|uniprotkb:Superkiller protein 6(gene name synonym)|uniprotkb:Extracellular mutant protein 20(gene name synonym)|uniprotkb:RRP41(gene name synonym)	psi-mi:c170l_human(display_long)|uniprotkb:KIAA0470L(gene name synonym)|uniprotkb:CEP170P1(gene name)|psi-mi:CEP170P1(display_short)|uniprotkb:CEP170L(gene name synonym)|uniprotkb:CEP170 pseudogene 1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553792|imex:IM-24995-4019	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003427|refseq:NP_011711.3|dip:DIP-2083N|mint:P46948|ensemblfungi:YGR195W(gene)|ensemblfungi:YGR195W_mRNA(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034473"(U1 snRNA 3'-end processing)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0034476"(U5 snRNA 3'-end processing)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071039"(nuclear polyadenylation-dependent CUT catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345|rcsb pdb:2WP8|rcsb pdb:4IFD|rcsb pdb:4OO1|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5G06|rcsb pdb:5JEA|rcsb pdb:5K36|rcsb pdb:5OKZ|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-429958|reactome:R-SCE-450385|reactome:R-SCE-450513|reactome:R-SCE-6791226	interpro:IPR026644|interpro:IPR029300|go:"GO:0042802"(identical protein binding)	-	crc64:C80EFFB528A43044	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:I7vEo0EUB1jZO+3v12H0LwVbgmo559292	rogid:Z/Rium0Kwj3ZUHa4WE5PPksPXdg9606	intact-crc:2CF256351712F43D|rigid:lfDGJ3ZVkgNWvR78oVXv8QekVDA	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P48232	uniprotkb:Q96L14	intact:EBI-28775|uniprotkb:D6W193|ensemblfungi:YNL086W	intact:EBI-743488	psi-mi:snapn_yeast(display_long)|uniprotkb:YNL086W(locus name)|uniprotkb:N2254(orf name)|uniprotkb:SNN1(gene name)|psi-mi:SNN1(display_short)|uniprotkb:SNAPIN-like protein 1(gene name synonym)	psi-mi:c170l_human(display_long)|uniprotkb:KIAA0470L(gene name synonym)|uniprotkb:CEP170P1(gene name)|psi-mi:CEP170P1(display_short)|uniprotkb:CEP170L(gene name synonym)|uniprotkb:CEP170 pseudogene 1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553800|imex:IM-24995-4021	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014313.1|sgd:S000005030|dip:DIP-1188N|mint:P48232|ensemblfungi:YNL086W(gene)|ensemblfungi:YNL086W_mRNA(transcript)|go:"GO:0005768"(endosome)|go:"GO:0007032"(endosome organization)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0032880"(regulation of protein localization)	interpro:IPR026644|interpro:IPR029300|go:"GO:0042802"(identical protein binding)	-	crc64:33200D2F0F729DA1	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:XCPaHuGC9oKD/3W0gY5ZY8jKtFs559292	rogid:Z/Rium0Kwj3ZUHa4WE5PPksPXdg9606	intact-crc:42D5A11F9A2A08B1|rigid:Nt9hHYoJV/gor2whzS37apTB0CM	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P38271	uniprotkb:Q96LP2	intact:EBI-12563|uniprotkb:D6VQC6|ensemblfungi:YBR129C	intact:EBI-10290827|ensembl:ENSP00000283357	psi-mi:opy1_yeast(display_long)|uniprotkb:OPY1(gene name)|psi-mi:OPY1(display_short)|uniprotkb:YBR129C(locus name)|uniprotkb:YBR1004(orf name)|uniprotkb:Overproduction-induced pheromone-resistant yeast protein 1(gene name synonym)	psi-mi:fa81b_human(display_long)|uniprotkb:FAM81B(gene name)|psi-mi:FAM81B(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553804|imex:IM-24995-4022	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YBR129C(gene)|ensemblfungi:YBR129C_mRNA(transcript)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:1902647"(negative regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016609(Uncharacterised conserved protein UCP013217, Opy1p)|refseq:NP_009687.1|sgd:S000000333|dip:DIP-4768N	refseq:NP_689761.2|ensembl:ENSG00000153347(gene)|ensembl:ENST00000283357(transcript)|go:"GO:0005634"(nucleus)|interpro:IPR029619|interpro:IPR029620	-	crc64:BB4BECCA7C67A5D9	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2020/03/03	rogid:97mFgMzTXaBI8NoMtAweXDE8i3s559292	rogid:V9VtnYUHk767ZnWUCuuxiUfJF+09606	intact-crc:DA11991EAB0C418F|rigid:n0Yhpn+39w5sOOefaMKMeX8eiVc	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P40956	uniprotkb:Q96MA1	intact:EBI-7968|uniprotkb:D6VTX2|ensemblfungi:YGL181W	intact:EBI-954466|uniprotkb:Q96SD2|ensembl:ENSP00000360500	psi-mi:gts1_yeast(display_long)|uniprotkb:YGL181W(locus name)|uniprotkb:GTS1(gene name)|psi-mi:GTS1(display_short)|uniprotkb:LSR1(gene name synonym)|uniprotkb:Protein LSR1(gene name synonym)	psi-mi:dmrtb_human(display_long)|uniprotkb:DMRTB1(gene name)|psi-mi:DMRTB1(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553812|imex:IM-24995-4024	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011334.1|sgd:S000003149|mint:P40956|dip:DIP-2746N|ensemblfungi:YGL181W(gene)|ensemblfungi:YGL181W_mRNA(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0006897"(endocytosis)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010512"(negative regulation of phosphatidylinositol biosynthetic process)|go:"GO:0030479"(actin cortical patch)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR037278|interpro:IPR038508	go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|ensembl:ENSG00000143006(gene)|ensembl:ENST00000371445(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007281"(germ cell development)|go:"GO:0007548"(sex differentiation)|go:"GO:0046872"(metal ion binding)|interpro:IPR001275(DM DNA-binding)|interpro:IPR026607|interpro:IPR036407|mint:Q96MA1|refseq:NP_149056.1|ensembl:ENSP00000360500	-	crc64:D687E3BF6B620795	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:8kgpssCRrHiTHsFaOH2nDK6EIjk559292	rogid:GU1xgsv/Oyy91PEorOlxBqAvIzc9606	intact-crc:86EE9406A385FFC7|rigid:uwFrWjBNeLBqWbAyoWmobXU9zyQ	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96MA1	uniprotkb:P39682	intact:EBI-954466|uniprotkb:Q96SD2|ensembl:ENSP00000360500	intact:EBI-612|uniprotkb:D6VZC9|uniprotkb:E9P8Z1|ensemblfungi:YML046W	psi-mi:dmrtb_human(display_long)|uniprotkb:DMRTB1(gene name)|psi-mi:DMRTB1(display_short)	psi-mi:prp39_yeast(display_long)|uniprotkb:YM9827.06(orf name)|uniprotkb:YML046W(locus name)|uniprotkb:PRP39(gene name)|psi-mi:PRP39(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553816|imex:IM-24995-4025	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|ensembl:ENSG00000143006(gene)|ensembl:ENST00000371445(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007281"(germ cell development)|go:"GO:0007548"(sex differentiation)|go:"GO:0046872"(metal ion binding)|interpro:IPR001275(DM DNA-binding)|interpro:IPR026607|interpro:IPR036407|mint:Q96MA1|refseq:NP_149056.1|ensembl:ENSP00000360500	refseq:NP_013667.1|sgd:S000004509|dip:DIP-812N|mint:P39682|ensemblfungi:YML046W(gene)|ensemblfungi:YML046W_mRNA(transcript)|go:"GO:0000243"(commitment complex)|go:"GO:0000395"(mRNA 5'-splice site recognition)|go:"GO:0005685"(U1 snRNP)|go:"GO:0071004"(U2-type prespliceosome)|interpro:IPR003107(RNA-processing protein, HAT helix)|interpro:IPR011990(Tetratricopeptide-like helical)|rcsb pdb:5ZWN|rcsb pdb:6G90|rcsb pdb:6N7P|rcsb pdb:6N7R|rcsb pdb:6N7X	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:GU1xgsv/Oyy91PEorOlxBqAvIzc9606	rogid:urVLzQFKnYT1bYOs3yRd9dd7lMk559292	intact-crc:8311861B2DC49FBB|rigid:FUMZ+VXl/dUFXcBRRDFQsjRZQLA	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q12329	uniprotkb:Q96MA1	intact:EBI-8571|uniprotkb:D6VSF3|ensemblfungi:YDR171W	intact:EBI-954466|uniprotkb:Q96SD2|ensembl:ENSP00000360500	psi-mi:hsp42_yeast(display_long)|uniprotkb:HSP42(gene name)|psi-mi:HSP42(display_short)|uniprotkb:YDR171W(locus name)|uniprotkb:YD9395.04(orf name)|uniprotkb:42 kDa heat shock protein(gene name synonym)	psi-mi:dmrtb_human(display_long)|uniprotkb:DMRTB1(gene name)|psi-mi:DMRTB1(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553820|imex:IM-24995-4026	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010456.1|sgd:S000002578|mint:Q12329|dip:DIP-2515N|ensemblfungi:YDR171W(gene)|ensemblfungi:YDR171W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0009408"(response to heat)|go:"GO:0009651"(response to salt stress)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043621"(protein self-association)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0140311"(protein sequestering activity)|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR031107	go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|ensembl:ENSG00000143006(gene)|ensembl:ENST00000371445(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007281"(germ cell development)|go:"GO:0007548"(sex differentiation)|go:"GO:0046872"(metal ion binding)|interpro:IPR001275(DM DNA-binding)|interpro:IPR026607|interpro:IPR036407|mint:Q96MA1|refseq:NP_149056.1|ensembl:ENSP00000360500	-	crc64:DF353A76493E3CE6	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:izvrv04fA3zcBqTeUeHD/erKGf4559292	rogid:GU1xgsv/Oyy91PEorOlxBqAvIzc9606	intact-crc:54D0485B93961F9A|rigid:uf8t2oK/UJIv8f9JHFrABaIU750	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P38340	uniprotkb:Q96MA1	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-954466|uniprotkb:Q96SD2|ensembl:ENSP00000360500	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:dmrtb_human(display_long)|uniprotkb:DMRTB1(gene name)|psi-mi:DMRTB1(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553824|imex:IM-24995-4027	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F	go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|ensembl:ENSG00000143006(gene)|ensembl:ENST00000371445(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007281"(germ cell development)|go:"GO:0007548"(sex differentiation)|go:"GO:0046872"(metal ion binding)|interpro:IPR001275(DM DNA-binding)|interpro:IPR026607|interpro:IPR036407|mint:Q96MA1|refseq:NP_149056.1|ensembl:ENSP00000360500	-	crc64:66699F37B0013088	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:GU1xgsv/Oyy91PEorOlxBqAvIzc9606	intact-crc:F8557EEF7D1CD323|rigid:XEOf/4DkhSl+14Sc5v3TJ+135Jo	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P38340	uniprotkb:Q96MF2	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-745680|uniprotkb:B4DUK9|uniprotkb:Q96HU5|ensembl:ENSP00000329200	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:stac3_human(display_long)|uniprotkb:STAC3(gene name)|psi-mi:STAC3(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553828|imex:IM-24995-4028	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F	refseq:NP_001273185.1|refseq:NP_001273186.1|refseq:NP_659501.1|refseq:XP_011536428.1|ensembl:ENSG00000185482(gene)|ensembl:ENST00000332782(transcript)|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0030315"(T-tubule)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:1901387"(positive regulation of voltage-gated calcium channel activity)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|interpro:IPR001452(Src homology-3)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR035736|interpro:IPR036028|interpro:IPR039688|mint:Q96MF2|rcsb pdb:2DB6|rcsb pdb:6B29|rcsb pdb:6UY7|rcsb pdb:6UY8|rcsb pdb:6UY9	-	crc64:66699F37B0013088	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:PzyVrp74OzLhtbODzinH5fHSGRc9606	intact-crc:4CB079E21B626DB7|rigid:7E6s5XTKhed7xn4oHkLVynXBEvY	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96MF2	uniprotkb:Q06132	intact:EBI-745680|uniprotkb:B4DUK9|uniprotkb:Q96HU5|ensembl:ENSP00000329200	intact:EBI-34377|uniprotkb:D6VYX6|ensemblfungi:YLR336C	psi-mi:stac3_human(display_long)|uniprotkb:STAC3(gene name)|psi-mi:STAC3(display_short)	psi-mi:sgd1_yeast(display_long)|uniprotkb:SGD1(gene name)|psi-mi:SGD1(display_short)|uniprotkb:YLR336C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553832|imex:IM-24995-4029	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001273185.1|refseq:NP_001273186.1|refseq:NP_659501.1|refseq:XP_011536428.1|ensembl:ENSG00000185482(gene)|ensembl:ENST00000332782(transcript)|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0030315"(T-tubule)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:1901387"(positive regulation of voltage-gated calcium channel activity)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|interpro:IPR001452(Src homology-3)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR035736|interpro:IPR036028|interpro:IPR039688|mint:Q96MF2|rcsb pdb:2DB6|rcsb pdb:6B29|rcsb pdb:6UY7|rcsb pdb:6UY8|rcsb pdb:6UY9	refseq:NP_013440.1|sgd:S000004328|mint:Q06132|dip:DIP-6333N|ensemblfungi:YLR336C(gene)|ensemblfungi:YLR336C_mRNA(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0006972"(hyperosmotic response)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0097078"(FAL1-SGD1 complex)|interpro:IPR003890(MIF4G-like, type 3)|interpro:IPR003891(Initiation factor eIF-4 gamma, MA3)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR016024(Armadillo-type fold)	-	-	crc64:8EEFDB8258407FF3	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:PzyVrp74OzLhtbODzinH5fHSGRc9606	rogid:FxZCxGejbcvEs/J2h1HEaWeVZLQ559292	intact-crc:39F9F20D673C2553|rigid:cHruQ2Bu9L+amyG30Q0+EETJouQ	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96MT8-3	uniprotkb:P01097	intact:EBI-11522539|ensembl:ENSP00000507703|ensembl:ENSP00000328382|ensembl:ENSP00000506728|ensembl:ENSP00000506791|ensembl:ENSP00000506828|ensembl:ENSP00000507228	intact:EBI-8874|ensemblfungi:YDL181W|uniprotkb:D6VRH1	psi-mi:q96mt8-3(display_long)|uniprotkb:CEP63(gene name)|psi-mi:CEP63(display_short)	psi-mi:atif_yeast(display_long)|uniprotkb:INH1(gene name)|psi-mi:INH1(display_short)|uniprotkb:ATP synthase F1 subunit epsilon(gene name synonym)|uniprotkb:D1305(orf name)|uniprotkb:YDL181W(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553836|imex:IM-24995-4030	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-741977(isoform-parent)|ensembl:ENST00000332047(transcript)|ensembl:ENST00000682042(transcript)|ensembl:ENST00000682800(transcript)|ensembl:ENST00000682858(transcript)|ensembl:ENST00000683177(transcript)|ensembl:ENST00000683861(transcript)|ensembl:ENSG00000182923(gene)|uniprotkb:Q96MT8-3(isoform-parent)	ensemblfungi:YDL181W(gene)|ensemblfungi:YDL181W_mRNA(transcript)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0042030"(ATPase inhibitor activity)|interpro:IPR007648(Mitochondrial ATPase inhibitor, IATP)|rcsb pdb:3ZIA|refseq:NP_010100.1|sgd:S000002340|mint:P01097|dip:DIP-2985N	-	-	crc64:E1AF73A47F63CE58	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:U0uvVcOCzA8Qp2cCB0ilixgd4Yc9606	rogid:3wsu4TOLAZdm97Kfhla8l4UKFEk559292	intact-crc:A335100F1A520F08|rigid:5ZYraKRCqZFQ5aHI1Bh7OK50qkY	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96M27	uniprotkb:P32562	intact:EBI-2560879|intact:EBI-28987821|uniprotkb:Q8NEZ7|uniprotkb:Q86Y42|uniprotkb:Q69YM8|uniprotkb:Q7L2U7|uniprotkb:Q96AJ3|uniprotkb:Q8IVL4|uniprotkb:Q8IVJ4|ensembl:ENSP00000296666	intact:EBI-4440|ensemblfungi:YMR001C|uniprotkb:D6VZH5	psi-mi:prrc1_human(display_long)|uniprotkb:PRRC1(gene name)|psi-mi:PRRC1(display_short)|uniprotkb:Proline-rich and coiled-coil-containing protein 1(gene name synonym)	psi-mi:cdc5_yeast(display_long)|uniprotkb:CDC5(gene name)|psi-mi:CDC5(display_short)|uniprotkb:MSD2(gene name synonym)|uniprotkb:PKX2(gene name synonym)|uniprotkb:YMR001C(locus name)|uniprotkb:YM8270.03C(orf name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553808|imex:IM-24995-4023	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_570721.1|refseq:NP_001273737.1|ensembl:ENSP00000296666|ensembl:ENST00000442138|ensembl:ENSP00000392873|ensembl:ENST00000512635|ensembl:ENSP00000421965|refseq:XP_006714592.1|ensembl:ENSG00000164244(gene)|ensembl:ENST00000296666(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0034199"(activation of protein kinase A activity)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|interpro:IPR026533|interpro:IPR026534|interpro:IPR029001|mint:Q96M27	ensemblfungi:YMR001C(gene)|ensemblfungi:YMR001C_mRNA(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0000922"(spindle pole)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0010458"(exit from mitosis)|go:"GO:0010696"(positive regulation of mitotic spindle pole body separation)|go:"GO:0019237"(centromeric DNA binding)|refseq:NP_013714.1|sgd:S000004603|reactome:R-SCE-6804115|reactome:R-SCE-156711|reactome:R-SCE-162658|reactome:R-SCE-2565942|dip:DIP-2321N|reactome:R-SCE-2500257|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0035025"(positive regulation of Rho protein signal transduction)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051301"(cell division)|go:"GO:0070194"(synaptonemal complex disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0110083"(positive regulation of protein localization to cell division site involved in mitotic actomyosin contractile ring assembly)|go:"GO:1902542"(regulation of protein localization to mitotic spindle pole body)|go:"GO:1903353"(regulation of nucleus organization)|go:"GO:1904750"(negative regulation of protein localization to nucleolus)|go:"GO:1905339"(positive regulation of cohesin unloading)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033695|interpro:IPR033701|interpro:IPR036947|rcsb pdb:6MF4|rcsb pdb:6MF5|rcsb pdb:6MF6	-	-	crc64:B5A25F1BBBEAA3DC	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:PLR9r6Zo0BDrdOArwQjuDiVPIik9606	rogid:XXSkltYvBA9Zkh0Kr5s1znazUC0559292	intact-crc:1272BB0B5007759B|rigid:VWvzr7qeIgW0D1wCs3qAY4B3Ng8	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96MT8-3	uniprotkb:Q04712	intact:EBI-11522539|ensembl:ENSP00000507703|ensembl:ENSP00000328382|ensembl:ENSP00000506728|ensembl:ENSP00000506791|ensembl:ENSP00000506828|ensembl:ENSP00000507228	intact:EBI-27790|uniprotkb:D6VZD2|ensemblfungi:YML043C	psi-mi:q96mt8-3(display_long)|uniprotkb:CEP63(gene name)|psi-mi:CEP63(display_short)	psi-mi:rrn11_yeast(display_long)|uniprotkb:YM9827.09C(orf name)|uniprotkb:YML043C(locus name)|uniprotkb:RRN11(gene name)|psi-mi:RRN11(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553844|imex:IM-24995-4032	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-741977(isoform-parent)|ensembl:ENST00000332047(transcript)|ensembl:ENST00000682042(transcript)|ensembl:ENST00000682800(transcript)|ensembl:ENST00000682858(transcript)|ensembl:ENST00000683177(transcript)|ensembl:ENST00000683861(transcript)|ensembl:ENSG00000182923(gene)|uniprotkb:Q96MT8-3(isoform-parent)	refseq:NP_013669.1|sgd:S000004507|dip:DIP-4542N|mint:Q04712|ensemblfungi:YML043C(gene)|ensemblfungi:YML043C_mRNA(transcript)|go:"GO:0001164"(RNA polymerase I core promoter sequence-specific DNA binding)|go:"GO:0001181"(RNA polymerase I general transcription initiation factor activity)|go:"GO:0005730"(nucleolus)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0042790"(nucleolar large rRNA transcription by RNA polymerase I)|go:"GO:0070860"(RNA polymerase I core factor complex)|interpro:IPR007224(RNA polymerase I specific initiation factor)|interpro:IPR016850(Core factor complex, Rrn11 component)|rcsb pdb:5N5Y|rcsb pdb:5N5Z|rcsb pdb:5N60|rcsb pdb:5N61|rcsb pdb:5O7X|rcsb pdb:5OA1|rcsb pdb:5W5Y|rcsb pdb:5W64|rcsb pdb:5W65|rcsb pdb:5W66|rcsb pdb:6RQH|rcsb pdb:6RQL|rcsb pdb:6RRD|rcsb pdb:6RUI|rcsb pdb:6RUO|rcsb pdb:6RWE|rcsb pdb:6TPS	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:U0uvVcOCzA8Qp2cCB0ilixgd4Yc9606	rogid:HeXVovHQGBfbg6FbSkFO9/T64hE559292	intact-crc:C7F1CD558E3AFFD1|rigid:AF4Ija845Zk96YrfkC9lGqse1sk	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96MT8-3	uniprotkb:P28004	intact:EBI-11522539|ensembl:ENSP00000507703|ensembl:ENSP00000328382|ensembl:ENSP00000506728|ensembl:ENSP00000506791|ensembl:ENSP00000506828|ensembl:ENSP00000507228	intact:EBI-20640|uniprotkb:D6VPI6|ensemblfungi:YAL032C	psi-mi:q96mt8-3(display_long)|uniprotkb:CEP63(gene name)|psi-mi:CEP63(display_short)	psi-mi:prp45_yeast(display_long)|uniprotkb:YAL032C(locus name)|uniprotkb:PRP45(gene name)|psi-mi:PRP45(display_short)|uniprotkb:FUN20(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553848|imex:IM-24995-4033	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-741977(isoform-parent)|ensembl:ENST00000332047(transcript)|ensembl:ENST00000682042(transcript)|ensembl:ENST00000682800(transcript)|ensembl:ENST00000682858(transcript)|ensembl:ENST00000683177(transcript)|ensembl:ENST00000683861(transcript)|ensembl:ENSG00000182923(gene)|uniprotkb:Q96MT8-3(isoform-parent)	refseq:NP_009370.1|sgd:S000000030|ensemblfungi:YAL032C(gene)|ensemblfungi:YAL032C_mRNA(transcript)|go:"GO:0000350"(generation of catalytic spliceosome for second transesterification step)|go:"GO:0005634"(nucleus)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|interpro:IPR004015(SKIP/SNW)|interpro:IPR017862|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|dip:DIP-2774N|mint:P28004	-	-	crc64:FE5A724186D7FE84	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:U0uvVcOCzA8Qp2cCB0ilixgd4Yc9606	rogid:qoHF1UsO3k+JOTOfigSuy2P84/k559292	intact-crc:5F01FE8005DF5291|rigid:EJ/r7IxMZYX8LJ5I6R1QwOOTrEs	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
intact:EBI-11522371	uniprotkb:Q96MT8-3	-	intact:EBI-11522539|ensembl:ENSP00000507703|ensembl:ENSP00000328382|ensembl:ENSP00000506728|ensembl:ENSP00000506791|ensembl:ENSP00000506828|ensembl:ENSP00000507228	psi-mi:yjr003c(display_short)|psi-mi:EBI-11522371(display_long)	psi-mi:q96mt8-3(display_long)|uniprotkb:CEP63(gene name)|psi-mi:CEP63(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553852|imex:IM-24995-4034	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	-	intact:EBI-741977(isoform-parent)|ensembl:ENST00000332047(transcript)|ensembl:ENST00000682042(transcript)|ensembl:ENST00000682800(transcript)|ensembl:ENST00000682858(transcript)|ensembl:ENST00000683177(transcript)|ensembl:ENST00000683861(transcript)|ensembl:ENSG00000182923(gene)|uniprotkb:Q96MT8-3(isoform-parent)	-	no-uniprot-update:	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:dYGrrP3JnrXO2rj4v/nTT64la6A4932	rogid:U0uvVcOCzA8Qp2cCB0ilixgd4Yc9606	intact-crc:DC4804D519366FBD|rigid:vrpSQQZOtDJzpIaBlSp7W6As+vI	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q03654	uniprotkb:Q96MT8-3	intact:EBI-476|uniprotkb:Q6B1D8|ensemblfungi:YMR213W|uniprotkb:D6W038	intact:EBI-11522539|ensembl:ENSP00000507703|ensembl:ENSP00000328382|ensembl:ENSP00000506728|ensembl:ENSP00000506791|ensembl:ENSP00000506828|ensembl:ENSP00000507228	psi-mi:cef1_yeast(display_long)|uniprotkb:CEF1(gene name)|psi-mi:CEF1(display_short)|uniprotkb:YMR213W(locus name)|uniprotkb:YM8261.07(orf name)|uniprotkb:NTC85(gene name synonym)|uniprotkb:PRP nineteen-associated complex protein 85(gene name synonym)|uniprotkb:PRP19-associated complex protein 85(gene name synonym)	psi-mi:q96mt8-3(display_long)|uniprotkb:CEP63(gene name)|psi-mi:CEP63(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553856|imex:IM-24995-4035	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013940.1|sgd:S000004826|ensemblfungi:YMR213W(gene)|ensemblfungi:YMR213W_mRNA(transcript)|go:"GO:0000350"(generation of catalytic spliceosome for second transesterification step)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000974"(Prp19 complex)|go:"GO:0003677"(DNA binding)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017930|interpro:IPR021786|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|rcsb pdb:7DCO|dip:DIP-1113N|mint:Q03654	intact:EBI-741977(isoform-parent)|ensembl:ENST00000332047(transcript)|ensembl:ENST00000682042(transcript)|ensembl:ENST00000682800(transcript)|ensembl:ENST00000682858(transcript)|ensembl:ENST00000683177(transcript)|ensembl:ENST00000683861(transcript)|ensembl:ENSG00000182923(gene)|uniprotkb:Q96MT8-3(isoform-parent)	-	crc64:A4C417A8B330EA9C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:AsbV7RtNk+8mCzLk2wZYqbULOFg559292	rogid:U0uvVcOCzA8Qp2cCB0ilixgd4Yc9606	intact-crc:0A57D4AA821DE17C|rigid:M1Vh7K1UdJklmCjhPNABta8/GdY	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P01098	uniprotkb:Q96MT8-3	intact:EBI-8080380|intact:MINT-2785764|uniprotkb:D6VRL9|ensemblfungi:YDL130W-A	intact:EBI-11522539|ensembl:ENSP00000507703|ensembl:ENSP00000328382|ensembl:ENSP00000506728|ensembl:ENSP00000506791|ensembl:ENSP00000506828|ensembl:ENSP00000507228	psi-mi:stf1_yeast(display_long)|uniprotkb:STF1(gene name)|psi-mi:STF1(display_short)|uniprotkb:AIS2(gene name synonym)|uniprotkb:ATP synthase F1 subunit epsilon(gene name synonym)|uniprotkb:YDL130BW(orf name)|uniprotkb:YDL130W-A(locus name)	psi-mi:q96mt8-3(display_long)|uniprotkb:CEP63(gene name)|psi-mi:CEP63(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553840|imex:IM-24995-4031	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010152.1|mint:P01098|interpro:IPR007648(Mitochondrial ATPase inhibitor, IATP)|sgd:S000007232|ensemblfungi:YDL130W-A_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0042030"(ATPase inhibitor activity)|go:"GO:0051117"(ATPase binding)|ensemblfungi:YDL130W-A(gene)	intact:EBI-741977(isoform-parent)|ensembl:ENST00000332047(transcript)|ensembl:ENST00000682042(transcript)|ensembl:ENST00000682800(transcript)|ensembl:ENST00000682858(transcript)|ensembl:ENST00000683177(transcript)|ensembl:ENST00000683861(transcript)|ensembl:ENSG00000182923(gene)|uniprotkb:Q96MT8-3(isoform-parent)	-	comment:mint|function:This is 1 of 2 proteins that can stabilize the ATPase-inhibitor complex, which normally dissociates when externally added ATP has been consumed	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:YxrqEhb1G8Ln3oLqBYbVRmFM7E4559292	rogid:U0uvVcOCzA8Qp2cCB0ilixgd4Yc9606	intact-crc:6BB7AE2432457654|rigid:EPQDMBePklXPquu8Tb6djvAIJwc	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P40454	uniprotkb:Q96MT8-3	intact:EBI-25278|uniprotkb:D6VVD4|ensemblfungi:YIL153W	intact:EBI-11522539|ensembl:ENSP00000507703|ensembl:ENSP00000328382|ensembl:ENSP00000506728|ensembl:ENSP00000506791|ensembl:ENSP00000506828|ensembl:ENSP00000507228	psi-mi:ptpa1_yeast(display_long)|uniprotkb:YIL153W(locus name)|uniprotkb:RRD1(gene name)|psi-mi:RRD1(display_short)|uniprotkb:NCS1(gene name synonym)|uniprotkb:YPA1(gene name synonym)|uniprotkb:Peptidyl-prolyl cis-trans isomerase PTPA-1(gene name synonym)|uniprotkb:Phosphotyrosyl phosphatase activator 1(gene name synonym)	psi-mi:q96mt8-3(display_long)|uniprotkb:CEP63(gene name)|psi-mi:CEP63(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553864|imex:IM-24995-4037	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012113.1|sgd:S000001415|mint:P40454|dip:DIP-5663N|ensemblfungi:YIL153W(gene)|ensemblfungi:YIL153W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006914"(autophagy)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008160"(protein tyrosine phosphatase activator activity)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0043618"(regulation of transcription from RNA polymerase II promoter in response to stress)|interpro:IPR004327(Phosphotyrosyl phosphatase activator, PTPA)|interpro:IPR037218|interpro:IPR043170|rcsb pdb:2IXO|rcsb pdb:2IXP	intact:EBI-741977(isoform-parent)|ensembl:ENST00000332047(transcript)|ensembl:ENST00000682042(transcript)|ensembl:ENST00000682800(transcript)|ensembl:ENST00000682858(transcript)|ensembl:ENST00000683177(transcript)|ensembl:ENST00000683861(transcript)|ensembl:ENSG00000182923(gene)|uniprotkb:Q96MT8-3(isoform-parent)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:It2q8WlpmvLEZ1fqpRF5Fypw9Q4559292	rogid:U0uvVcOCzA8Qp2cCB0ilixgd4Yc9606	intact-crc:60FBFC112C85D3B5|rigid:Ql13sIEA35Z0th8Tdvq89H0re2s	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96PU8	uniprotkb:P38151	intact:EBI-945792|uniprotkb:Q2I375|uniprotkb:Q5MJQ1|uniprotkb:Q969L9|uniprotkb:Q96EJ3|uniprotkb:Q96KA3|uniprotkb:Q96PU6|uniprotkb:Q96PU7|uniprotkb:Q9P0X6|uniprotkb:Q9P0X7|uniprotkb:Q9P0X8|uniprotkb:Q9P0X9|uniprotkb:Q9P0Y0|uniprotkb:Q9P0Y1|ensembl:ENSP00000355094	intact:EBI-12968|uniprotkb:D6VQM8|ensemblfungi:YBR233W	psi-mi:qki_human(display_long)|uniprotkb:QKI(gene name)|psi-mi:QKI(display_short)|uniprotkb:HKQ(gene name synonym)	psi-mi:pbp2_yeast(display_long)|uniprotkb:YBR1531(orf name)|uniprotkb:YBR233W(locus name)|uniprotkb:PBP2(gene name)|psi-mi:PBP2(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553868|imex:IM-24995-4038	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006766.1|refseq:NP_996735.1|refseq:NP_996736.1|refseq:NP_996737.1|refseq:NP_001288014.1|refseq:XP_011534561.1|ensembl:ENSG00000112531(gene)|ensembl:ENST00000361752(transcript)|go:"GO:0001570"(vasculogenesis)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0006417"(regulation of translation)|go:"GO:0007286"(spermatid development)|go:"GO:0008380"(RNA splicing)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0042552"(myelination)|go:"GO:0042692"(muscle cell differentiation)|go:"GO:0042759"(long-chain fatty acid biosynthetic process)|go:"GO:0045202"(synapse)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0051028"(mRNA transport)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR032367|interpro:IPR032377|interpro:IPR036612|mint:Q96PU8|rcsb pdb:4JVH|reactome:R-HSA-6802952	sgd:S000000437|refseq:NP_009792.3|dip:DIP-4947N|ensemblfungi:YBR233W(gene)|ensemblfungi:YBR233W_mRNA(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0051252"(regulation of RNA metabolic process)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR036612	-	-	crc64:638846509BCE1840	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:7dcw5OyNAhQTE+yTch3qbSlZJdE9606	rogid:zcN9K+pivnit4l3Cl75wfk5F4VI559292	intact-crc:5C397206837C7967|rigid:LpPFQcO9qpi9sQJVGxaytAmOhKc	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P38340	uniprotkb:Q96PU8	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-945792|uniprotkb:Q2I375|uniprotkb:Q5MJQ1|uniprotkb:Q969L9|uniprotkb:Q96EJ3|uniprotkb:Q96KA3|uniprotkb:Q96PU6|uniprotkb:Q96PU7|uniprotkb:Q9P0X6|uniprotkb:Q9P0X7|uniprotkb:Q9P0X8|uniprotkb:Q9P0X9|uniprotkb:Q9P0Y0|uniprotkb:Q9P0Y1|ensembl:ENSP00000355094	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:qki_human(display_long)|uniprotkb:QKI(gene name)|psi-mi:QKI(display_short)|uniprotkb:HKQ(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553872|imex:IM-24995-4039	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F	refseq:NP_006766.1|refseq:NP_996735.1|refseq:NP_996736.1|refseq:NP_996737.1|refseq:NP_001288014.1|refseq:XP_011534561.1|ensembl:ENSG00000112531(gene)|ensembl:ENST00000361752(transcript)|go:"GO:0001570"(vasculogenesis)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0006417"(regulation of translation)|go:"GO:0007286"(spermatid development)|go:"GO:0008380"(RNA splicing)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0042552"(myelination)|go:"GO:0042692"(muscle cell differentiation)|go:"GO:0042759"(long-chain fatty acid biosynthetic process)|go:"GO:0045202"(synapse)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0051028"(mRNA transport)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR032367|interpro:IPR032377|interpro:IPR036612|mint:Q96PU8|rcsb pdb:4JVH|reactome:R-HSA-6802952	-	crc64:66699F37B0013088	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:7dcw5OyNAhQTE+yTch3qbSlZJdE9606	intact-crc:3DE9DB69D0E226BD|rigid:gys1RPpQVAeyV88aDboHQby7lpw	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P32571	uniprotkb:Q96MT8-3	intact:EBI-19840|uniprotkb:D6VS55|ensemblfungi:YDR069C	intact:EBI-11522539|ensembl:ENSP00000507703|ensembl:ENSP00000328382|ensembl:ENSP00000506728|ensembl:ENSP00000506791|ensembl:ENSP00000506828|ensembl:ENSP00000507228	psi-mi:ubp4_yeast(display_long)|uniprotkb:DOA4(gene name)|psi-mi:DOA4(display_short)|uniprotkb:MUT4(gene name synonym)|uniprotkb:SSV7(gene name synonym)|uniprotkb:YDR069C(locus name)|uniprotkb:YD9609.23C(orf name)|uniprotkb:YD8554.02C(orf name)|uniprotkb:D4270(orf name)|uniprotkb:NPI2(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 4(gene name synonym)|uniprotkb:Deubiquitinating enzyme 4(gene name synonym)|uniprotkb:Vacuole biogenesis protein SSV7(gene name synonym)|uniprotkb:Ubiquitin thioesterase 4(gene name synonym)|uniprotkb:DOS1(gene name synonym)|uniprotkb:UBP4(gene name synonym)	psi-mi:q96mt8-3(display_long)|uniprotkb:CEP63(gene name)|psi-mi:CEP63(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553860|imex:IM-24995-4036	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002476|ensemblfungi:YDR069C(gene)|ensemblfungi:YDR069C_mRNA(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005739"(mitochondrion)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0010992"(ubiquitin recycling)|go:"GO:0010995"(free ubiquitin chain depolymerization)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0031902"(late endosome membrane)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0070676"(intralumenal vesicle formation)|go:"GO:1904669"(ATP export)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR001763(Rhodanese-like)|interpro:IPR018200|interpro:IPR028889|interpro:IPR036873|interpro:IPR038765|refseq:NP_010354.3|dip:DIP-5298N|mint:P32571	intact:EBI-741977(isoform-parent)|ensembl:ENST00000332047(transcript)|ensembl:ENST00000682042(transcript)|ensembl:ENST00000682800(transcript)|ensembl:ENST00000682858(transcript)|ensembl:ENST00000683177(transcript)|ensembl:ENST00000683861(transcript)|ensembl:ENSG00000182923(gene)|uniprotkb:Q96MT8-3(isoform-parent)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:UTBSWmpygyxo1ygxp/sQ8wgqnMo559292	rogid:U0uvVcOCzA8Qp2cCB0ilixgd4Yc9606	intact-crc:8862C06523F00311|rigid:kI8D2HOV+rSIzOY7Cz4dnMIPdhc	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q15415	uniprotkb:Q99383	intact:EBI-8642021|uniprotkb:B2R916|intact:MINT-8163253|ensembl:ENSP00000250831|ensembl:ENSP00000307155	intact:EBI-11783|uniprotkb:Q02741|ensemblfungi:YOL123W|uniprotkb:D6W1U5	psi-mi:rby1f_human(display_long)|uniprotkb:RBMY1F(gene name)|psi-mi:RBMY1F(display_short)|uniprotkb:RBMY1J(gene name)|psi-mi:RBMY1J(display_short)|uniprotkb:Y chromosome RNA recognition motif 2(gene name synonym)|uniprotkb:YRRM2(gene name synonym)	psi-mi:hrp1_yeast(display_long)|uniprotkb:YOL123W(locus name)|uniprotkb:HRP1(gene name)|psi-mi:HRP1(display_short)|uniprotkb:NAB4(gene name synonym)|uniprotkb:NAB5(gene name synonym)|uniprotkb:Cleavage factor IB(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553916|imex:IM-24995-4050	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001290339.1|refseq:NP_001006117.2|refseq:NP_689798.1|ensembl:ENSG00000169800(gene)|ensembl:ENSG00000226941(gene)|ensembl:ENST00000250831(transcript)|ensembl:ENST00000303766(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016607"(nuclear speck)|go:"GO:0042802"(identical protein binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012604(RBM1CTR)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979	ensemblfungi:YOL123W(gene)|ensemblfungi:YOL123W_mRNA(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005849"(mRNA cleavage factor complex)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0072423"(response to DNA damage checkpoint signaling)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034155|interpro:IPR034156|interpro:IPR035979|rcsb pdb:2CJK|rcsb pdb:2KM8|go:"GO:0005737"(cytoplasm)|refseq:NP_014518.1|sgd:S000005483|dip:DIP-1371N	-	comment:mint	crc64:1B231069437B093D	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:lEyv+LmtOFRifaC5g6jDlh5WCnM9606	rogid:8EWzxKR7UWoJhDGSB/0C2d0Qn6k559292	intact-crc:96C2E81A18080059|rigid:307E09SLKg3CbMqdndHvbV6z96I	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P38159	uniprotkb:Q99383	intact:EBI-743526|ensembl:ENSP00000359645|uniprotkb:Q5JQ67|uniprotkb:Q969R3|uniprotkb:D3DWH0|uniprotkb:E9PG86|uniprotkb:Q8N8Y7|uniprotkb:B4E3U4	intact:EBI-11783|uniprotkb:Q02741|ensemblfungi:YOL123W|uniprotkb:D6W1U5	psi-mi:rbmx_human(display_long)|uniprotkb:Glycoprotein p43(gene name synonym)|uniprotkb:RBMX(gene name)|psi-mi:RBMX(display_short)|uniprotkb:HNRPG(gene name synonym)|uniprotkb:RBMXP1(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein G(gene name synonym)	psi-mi:hrp1_yeast(display_long)|uniprotkb:YOL123W(locus name)|uniprotkb:HRP1(gene name)|psi-mi:HRP1(display_short)|uniprotkb:NAB4(gene name synonym)|uniprotkb:NAB5(gene name synonym)|uniprotkb:Cleavage factor IB(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553912|imex:IM-24995-4049	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000147274(gene)|ensembl:ENST00000320676(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000791"(euchromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0044530"(supraspliceosomal complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0006509"(membrane protein ectodomain proteolysis)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012604(RBM1CTR)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|mint:P38159|rcsb pdb:2MB0|rcsb pdb:2MKS|reactome:R-HSA-72163|reactome:R-HSA-72203|reactome:R-HSA-9013418|reactome:R-HSA-9013422|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273|refseq:NP_002130.2|refseq:NP_001158275.1|dip:DIP-34447N	ensemblfungi:YOL123W(gene)|ensemblfungi:YOL123W_mRNA(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005849"(mRNA cleavage factor complex)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0072423"(response to DNA damage checkpoint signaling)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034155|interpro:IPR034156|interpro:IPR035979|rcsb pdb:2CJK|rcsb pdb:2KM8|go:"GO:0005737"(cytoplasm)|refseq:NP_014518.1|sgd:S000005483|dip:DIP-1371N	-	-	crc64:1B231069437B093D	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:ocCkdy9PxjeVLUQf0tMVCEhFfO89606	rogid:8EWzxKR7UWoJhDGSB/0C2d0Qn6k559292	intact-crc:4E16AC8C06BB87BD|rigid:cUrutqqJPJxYJQwe6Pf/PkZWYfc	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O43765	uniprotkb:Q99380	intact:EBI-347996|ensembl:ENSP00000221566|ensembl:ENSP00000503397|ensembl:ENSP00000504495|uniprotkb:Q9BTZ9|intact:EBI-1045243|uniprotkb:Q6FIA9|uniprotkb:D6W610	intact:EBI-12689|uniprotkb:D6VRC4|ensemblfungi:YDL232W	psi-mi:sgta_human(display_long)|uniprotkb:SGTA(gene name)|psi-mi:SGTA(display_short)|uniprotkb:SGT(gene name synonym)|uniprotkb:Alpha-SGT(gene name synonym)|uniprotkb:Vpu-binding protein(gene name synonym)|uniprotkb:SGT1(gene name synonym)	psi-mi:ost4_yeast(display_long)|uniprotkb:OST4(gene name)|psi-mi:OST4(display_short)|uniprotkb:Oligosaccharyl transferase 4 kDa subunit(gene name synonym)|uniprotkb:YDL232W(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553908|imex:IM-24995-4048	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:4CPG|rcsb pdb:4GOD|rcsb pdb:4GOE|rcsb pdb:4GOF|reactome:R-HSA-9609523|rcsb pdb:2VYI|ensembl:ENSG00000104969(gene)|ensembl:ENST00000221566(transcript)|ensembl:ENST00000676943(transcript)|ensembl:ENST00000677149(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072380"(TRC complex)|go:"GO:0098850"(extrinsic component of synaptic vesicle membrane)|go:"GO:1903070"(negative regulation of ER-associated ubiquitin-dependent protein catabolic process)|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)|go:"GO:1903646"(positive regulation of chaperone-mediated protein folding)|go:"GO:1904288"(BAT3 complex binding)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR032374|mint:O43765|refseq:XP_011526480.1|refseq:NP_003012.1	ensemblfungi:YDL232W(gene)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0008250"(oligosaccharyltransferase complex)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030674"(protein-macromolecule adaptor activity)|interpro:IPR018943|interpro:IPR036330|rcsb pdb:1RKL|rcsb pdb:6C26|rcsb pdb:6EZN|ensemblfungi:YDL232W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|refseq:NP_010049.1|sgd:S000002391|dip:DIP-2457N	-	-	crc64:BA14A9C3B197F12A	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:r/Cyj4UJk/cS8QdrbjhTZMPCigI9606	rogid:JOKTdHukiAM2CO87EYm3TT8UxDQ559292	intact-crc:A64452D338F72CF3|rigid:AZC00OrV2+nxyUj43yl1ONPojW4	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96EQ0	uniprotkb:Q99380	intact:EBI-744081|ensembl:ENSP00000370395	intact:EBI-12689|uniprotkb:D6VRC4|ensemblfungi:YDL232W	psi-mi:sgtb_human(display_long)|uniprotkb:Beta-SGT(gene name synonym)|uniprotkb:Small glutamine-rich protein with tetratricopeptide repeats 2(gene name synonym)|uniprotkb:SGTB(gene name)|psi-mi:SGTB(display_short)|uniprotkb:SGT2(gene name synonym)	psi-mi:ost4_yeast(display_long)|uniprotkb:OST4(gene name)|psi-mi:OST4(display_short)|uniprotkb:Oligosaccharyl transferase 4 kDa subunit(gene name synonym)|uniprotkb:YDL232W(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553904|imex:IM-24995-4047	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_061945.1|refseq:XP_005248605.1|ensembl:ENSG00000197860(gene)|ensembl:ENST00000381007(transcript)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0072380"(TRC complex)|go:"GO:1903646"(positive regulation of chaperone-mediated protein folding)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR032374	ensemblfungi:YDL232W(gene)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0008250"(oligosaccharyltransferase complex)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030674"(protein-macromolecule adaptor activity)|interpro:IPR018943|interpro:IPR036330|rcsb pdb:1RKL|rcsb pdb:6C26|rcsb pdb:6EZN|ensemblfungi:YDL232W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|refseq:NP_010049.1|sgd:S000002391|dip:DIP-2457N	-	-	crc64:BA14A9C3B197F12A	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:emIgH8U/yVmXT00Ty9yybIqQqas9606	rogid:JOKTdHukiAM2CO87EYm3TT8UxDQ559292	intact-crc:E71CE08EAB0CA0D5|rigid:gJrsNUC7PlhReDpRaF6wp5nPNLo	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q99288	uniprotkb:O76003	intact:EBI-30580|uniprotkb:Q05314|uniprotkb:P87337|uniprotkb:Q7LHX4|uniprotkb:D6VS38|ensemblfungi:YDR051C	intact:EBI-374781|uniprotkb:Q96CE0|uniprotkb:Q9P1B0|uniprotkb:Q9P1B1|uniprotkb:B3KMP7|uniprotkb:B3KMQ5|uniprotkb:Q5JV01|ensembl:ENSP00000330836|ensembl:ENSP00000357633|ensembl:ENSP00000435445|uniprotkb:D3DRG2	psi-mi:det1_yeast(display_long)|uniprotkb:DET1(gene name)|psi-mi:DET1(display_short)|uniprotkb:D4202(orf name)|uniprotkb:YDR051C(locus name)|uniprotkb:Decreased ergosterol transport protein 1(gene name synonym)	psi-mi:glrx3_human(display_long)|uniprotkb:GLRX3(gene name)|psi-mi:GLRX3(display_short)|uniprotkb:Thioredoxin-like protein 2(gene name synonym)|uniprotkb:PKC-interacting cousin of thioredoxin(gene name synonym)|uniprotkb:PKC-theta-interacting protein(gene name synonym)|uniprotkb:PICOT(gene name synonym)|uniprotkb:HUSSY-22(orf name)|uniprotkb:TXNL2(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553900|imex:IM-24995-4046	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002458|refseq:NP_010336.3|dip:DIP-1816N|mint:Q99288|ensemblfungi:YDR051C(gene)|ensemblfungi:YDR051C_mRNA(transcript)|go:"GO:0003993"(acid phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016311"(dephosphorylation)|go:"GO:0016791"(phosphatase activity)|go:"GO:0032366"(intracellular sterol transport)|interpro:IPR001345(Phosphoglycerate/bisphosphoglycerate mutase)|interpro:IPR013078(Phosphoglycerate mutase)|interpro:IPR029033	ensembl:ENSG00000108010(gene)|ensembl:ENST00000331244(transcript)|ensembl:ENST00000368644(transcript)|ensembl:ENST00000481034(transcript)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0003723"(RNA binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0030018"(Z disc)|go:"GO:0030425"(dendrite)|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051536"(iron-sulfur cluster binding)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|go:"GO:0097573"(glutathione oxidoreductase activity)|interpro:IPR002109(Glutaredoxin)|interpro:IPR004480(Glutaredoxin-related protein)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR033658|interpro:IPR036249|mint:O76003|rcsb pdb:2DIY|rcsb pdb:2WZ9|rcsb pdb:2YAN|rcsb pdb:3ZYW|reactome:R-HSA-917937|refseq:NP_001186797.1|refseq:NP_006532.2|dip:DIP-31306N	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:vwXFLCqrDTeOaIJG7tr6C6a1cFs559292	rogid:iKUSt6zbNzzXSKvW+vXMq3hKsEM9606	intact-crc:9A951611B0F9CB7A|rigid:a92h/SOoY3koogqVQEMXPj4UnsY	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P53286	uniprotkb:Q96Q35-2	intact:EBI-3796|uniprotkb:D6VUS2|ensemblfungi:YGR142W	intact:EBI-11533409|ensembl:ENSP00000376086|ensembl:ENSP00000412073	psi-mi:btn2_yeast(display_long)|uniprotkb:YGR142W(locus name)|uniprotkb:BTN2(gene name)|psi-mi:BTN2(display_short)|uniprotkb:Batten disease protein 2(gene name synonym)	psi-mi:q96q35-2(display_long)|uniprotkb:FLACC1(gene name)|psi-mi:FLACC1(display_short)|uniprotkb:ALS2CR12(gene name synonym)|uniprotkb:Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 12 protein(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553876|imex:IM-24995-4040	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003374|refseq:NP_011658.3|dip:DIP-5534N|mint:P53286|ensemblfungi:YGR142W(gene)|ensemblfungi:YGR142W_mRNA(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005634"(nucleus)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006865"(amino acid transport)|go:"GO:0006885"(regulation of pH)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051087"(chaperone binding)|go:"GO:0140311"(protein sequestering activity)	intact:EBI-750451(isoform-parent)|uniprotkb:Q96Q35-2(isoform-parent)|ensembl:ENSG00000155749(gene)|ensembl:ENST00000392257(transcript)|ensembl:ENST00000439709(transcript)	-	crc64:E7AE1EB1E3612F3E	isoform-comment:No experimental confirmation available.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:Cu27xkwGMNyS4zLvUaG1UeH2mE0559292	rogid:bdqsMHSGebh2qVAwEO8DhTbZOHM9606	intact-crc:3AF914F76E2F71A8|rigid:fCuK39rzQsrSPULT0uqqR2hP8KQ	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q99189	uniprotkb:Q13557-8	intact:EBI-11597|ensemblfungi:YOR160W|uniprotkb:D6W2L7	intact:EBI-11534483|ensembl:ENSP00000296402|ensembl:ENSP00000369098	psi-mi:mtr10_yeast(display_long)|uniprotkb:YOR160W(locus name)|uniprotkb:MTR10(gene name)|psi-mi:MTR10(display_short)	psi-mi:q13557-8(display_long)|uniprotkb:CAMKD(gene name synonym)|uniprotkb:CAMK2D(gene name)|psi-mi:CAMK2D(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553892|imex:IM-24995-4044	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005737"(cytoplasm)|go:"GO:0006403"(RNA localization)|go:"GO:0006404"(RNA import into nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0034399"(nuclear periphery)|go:"GO:0051031"(tRNA transport)|go:"GO:0061015"(snRNA import into nucleus)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013598(Exportin-1/Importin-beta-like)|interpro:IPR016024(Armadillo-type fold)|ensemblfungi:YOR160W(gene)|ensemblfungi:YOR160W_mRNA(transcript)|go:"GO:0005634"(nucleus)|refseq:NP_014803.1|sgd:S000005686|dip:DIP-2358N	intact:EBI-351018(isoform-parent)|ensembl:ENSG00000145349(gene)|ensembl:ENST00000296402(transcript)|ensembl:ENST00000379773(transcript)|uniprotkb:Q13557-8(isoform-parent)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:EbfcB0um6KIUegXNsKf6yAD8VRs559292	rogid:44T/I8JdalScCNE5Vp/H+PnfdFo9606	intact-crc:E05E10239D134348|rigid:coBbrglAnlIAVfwMr7tOu50OVkI	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96S82	uniprotkb:P53243	intact:EBI-348604|uniprotkb:Q96I03|ensembl:ENSP00000378518|ensembl:ENSP00000454828|ensembl:ENSP00000457703|ensembl:ENSP00000457708|ensembl:ENSP00000500164|ensembl:ENSP00000500266|ensembl:ENSP00000500442|ensembl:ENSP00000500520|ensembl:ENSP00000500882|ensembl:ENSP00000354883|uniprotkb:D3DW57	intact:EBI-23197|uniprotkb:D6VUK1|ensemblfungi:YGR067C	psi-mi:ubl7_human(display_long)|uniprotkb:Ubiquitin-like protein SB132(gene name synonym)|uniprotkb:Bone marrow stromal cell ubiquitin-like protein(gene name synonym)|uniprotkb:UBL7(gene name)|psi-mi:UBL7(display_short)|uniprotkb:BMSCUBP(gene name synonym)|uniprotkb:SB132(orf name)	psi-mi:yg2a_yeast(display_long)|uniprotkb:YGR067C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553888|imex:IM-24995-4043	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_116296.1|refseq:NP_957717.1|ensembl:ENST00000361351(transcript)|ensembl:ENST00000395081(transcript)|ensembl:ENST00000564488(transcript)|ensembl:ENST00000565335(transcript)|ensembl:ENST00000567435(transcript)|ensembl:ENST00000673054(transcript)|ensembl:ENST00000673073(transcript)|ensembl:ENST00000673120(transcript)|ensembl:ENST00000673153(transcript)|ensembl:ENST00000673461(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR029071|rcsb pdb:2CWB|rcsb pdb:2DEN|ensembl:ENSG00000138629(gene)|ensembl:ENSG00000288408(gene)|refseq:NP_001273668.1|refseq:NP_001273669.1|refseq:NP_001273670.1|refseq:NP_001273671.1	sgd:S000003299|refseq:NP_011581.4|dip:DIP-2819N|mint:P53243|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|ensemblfungi:YGR067C(gene)|ensemblfungi:YGR067C_mRNA(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)	-	-	crc64:BB936C265B7B263F	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:4E0ErEIkP/AQb+OHRuOd5wbXU/s9606	rogid:/qkApijbHr7FKeeSJZ6IczHMf28559292	intact-crc:3B611B43B4CA8671|rigid:S8zvAGQgBgIYqHUo1UXlwXsgxy8	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96QF0-2	uniprotkb:P32502	intact:EBI-747865|ensembl:ENSP00000247833	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:q96qf0-2(display_long)|uniprotkb:alpha1(isoform synonym)|uniprotkb:RAB3IP(gene name)|psi-mi:RAB3IP(display_short)|uniprotkb:Rabin-3(gene name synonym)|uniprotkb:SSX2-interacting protein(gene name synonym)|uniprotkb:RABIN8(gene name synonym)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553884|imex:IM-24995-4042	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-747844(rab3i_human)|ensembl:ENSG00000127328(gene)|ensembl:ENST00000247833(transcript)|uniprotkb:Q96QF0-2(isoform-parent)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731	-	-	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Vpmox/vANEwz2l+XaBdJslXrwyo9606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:25BFC5B967A6934E|rigid:RCBuD0oAg2xoF8AhY+F76pm7vTg	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96Q35-2	uniprotkb:Q12161	intact:EBI-11533409|ensembl:ENSP00000376086|ensembl:ENSP00000412073	intact:EBI-34372|uniprotkb:D6W213|ensemblfungi:YOL054W	psi-mi:q96q35-2(display_long)|uniprotkb:FLACC1(gene name)|psi-mi:FLACC1(display_short)|uniprotkb:ALS2CR12(gene name synonym)|uniprotkb:Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 12 protein(gene name synonym)	psi-mi:psh1_yeast(display_long)|uniprotkb:PSH1(gene name)|psi-mi:PSH1(display_short)|uniprotkb:POB3/SPT16 histone-associated protein 1(gene name synonym)|uniprotkb:O1263(orf name)|uniprotkb:YOL054W(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553880|imex:IM-24995-4041	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-750451(isoform-parent)|uniprotkb:Q96Q35-2(isoform-parent)|ensembl:ENSG00000155749(gene)|ensembl:ENST00000392257(transcript)|ensembl:ENST00000439709(transcript)	refseq:NP_014587.1|sgd:S000005415|mint:Q12161|dip:DIP-6481N|ensemblfungi:YOL054W(gene)|ensemblfungi:YOL054W_mRNA(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907	-	isoform-comment:No experimental confirmation available.	crc64:CE0ECBCB6D465554	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:bdqsMHSGebh2qVAwEO8DhTbZOHM9606	rogid:AvPMRd/GjfaTyQjEfMPhBVcvOs4559292	intact-crc:CF793D35510DB3D8|rigid:9Lw5c07SoW0m9ntpxDUfHEqxDkQ	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P38635	uniprotkb:Q99259	intact:EBI-2045554|uniprotkb:D6VTQ5|ensemblfungi:YFR025C	intact:EBI-743184|ensembl:ENSP00000350928|uniprotkb:Q53TQ7|uniprotkb:Q9BU91|uniprotkb:Q9UHH4|uniprotkb:Q49AK1	psi-mi:his9_yeast(display_long)|uniprotkb:YFR025C(locus name)|uniprotkb:HIS2(gene name)|psi-mi:HIS2(display_short)	psi-mi:dce1_human(display_long)|uniprotkb:Glutamate decarboxylase 67 kDa isoform(gene name synonym)|uniprotkb:67 kDa glutamic acid decarboxylase(gene name synonym)|uniprotkb:GAD1(gene name)|psi-mi:GAD1(display_short)|uniprotkb:GAD(gene name synonym)|uniprotkb:GAD67(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553896|imex:IM-24995-4045	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_116681.1|sgd:S000001921|interpro:IPR010140(Histidinol phosphate phosphatase, HisJ)|interpro:IPR004013(PHP, C-terminal)|interpro:IPR016195(Polymerase and histidinol phosphatase-like)|mint:P38635|ensemblfungi:YFR025C(gene)|ensemblfungi:YFR025C_mRNA(transcript)|go:"GO:0000105"(histidine biosynthetic process)|go:"GO:0004401"(histidinol-phosphatase activity)|go:"GO:0005737"(cytoplasm)	refseq:NP_000808.2|refseq:NP_038473.2|ensembl:ENSG00000128683(gene)|ensembl:ENST00000358196(transcript)|go:"GO:0004351"(glutamate decarboxylase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0060077"(inhibitory synapse)|go:"GO:0061202"(clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006538"(glutamate catabolic process)|go:"GO:0006540"(glutamate decarboxylation to succinate)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0009449"(gamma-aminobutyric acid biosynthetic process)|go:"GO:0012506"(vesicle membrane)|go:"GO:0016595"(glutamate binding)|go:"GO:0018352"(protein-pyridoxal-5-phosphate linkage)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0035176"(social behavior)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0042136"(neurotransmitter biosynthetic process)|go:"GO:0042493"|go:"GO:0043679"(axon terminus)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048786"(presynaptic active zone)|interpro:IPR002129(Pyridoxal phosphate-dependent decarboxylase)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR021115|mint:Q99259|rcsb pdb:2OKJ|rcsb pdb:3VP6|reactome:R-HSA-888568|reactome:R-HSA-888590|reactome:R-HSA-9022927|refseq:XP_011509224.1|refseq:XP_005246501.1|refseq:XP_016859245.1|refseq:XP_016859247.1|dip:DIP-29292N	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:3gGqFDbJWtM4it1O4HJjk6KoTL4559292	rogid:tFlqx11D9m3HofJUdpZynm2jKIQ9606	intact-crc:F1EB82020DDEAEBB|rigid:RPeVitSwH4UGTGHiXyA/r5yXpQU	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q99836	uniprotkb:P38340	intact:EBI-447677|uniprotkb:P78397|uniprotkb:Q53XS7|uniprotkb:B4DKH8|uniprotkb:B4DKU4|uniprotkb:J3KPU4|uniprotkb:J3KQ87|uniprotkb:J3KQJ6|uniprotkb:B4DQ60|uniprotkb:B4DQ72|ensembl:ENSP00000379625|ensembl:ENSP00000498360	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:myd88_human(display_long)|uniprotkb:MYD88(gene name)|psi-mi:MYD88(display_short)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553956|imex:IM-24995-4060	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001166037.1|refseq:NP_001166039.1|refseq:NP_001166040.1|refseq:NP_002459.2|dip:DIP-31349N|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032740"(positive regulation of interleukin-17 production)|go:"GO:0032747"(positive regulation of interleukin-23 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034158"(toll-like receptor 8 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042802"(identical protein binding)|go:"GO:0042832"(defense response to protozoan)|go:"GO:0050671"(positive regulation of lymphocyte proliferation)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043621"(protein self-association)|go:"GO:0045087"(innate immune response)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:1902622"(regulation of neutrophil migration)|go:"GO:2000338"("regulation of chemokine (C-X-C motif) ligand 1 production")|go:"GO:2000341"("regulation of chemokine (C-X-C motif) ligand 2 production")|interpro:IPR000157(Toll-Interleukin receptor)|interpro:IPR000488(Death)|interpro:IPR011029(DEATH-like)|interpro:IPR017281(Myeloid differentiation primary response protein MyD88)|interpro:IPR034249|interpro:IPR035897|mint:Q99836|rcsb pdb:2JS7|rcsb pdb:2Z5V|rcsb pdb:3MOP|rcsb pdb:4DOM|rcsb pdb:4EO7|rcsb pdb:6I3N|rcsb pdb:7BEQ|rcsb pdb:7BER|rcsb pdb:7L6W|reactome:R-HSA-1236974|reactome:R-HSA-1257604|reactome:R-HSA-166058|reactome:R-HSA-1810476|reactome:R-HSA-209543|reactome:R-HSA-3134963|reactome:R-HSA-5602498|reactome:R-HSA-5602680|reactome:R-HSA-5603037|reactome:R-HSA-5603041|reactome:R-HSA-6811558|reactome:R-HSA-9020702|reactome:R-HSA-975110|reactome:R-HSA-975155|reactome:R-HSA-975871|reactome:R-HSA-975138|ensembl:ENSG00000172936(gene)|ensembl:ENST00000396334(transcript)|ensembl:ENST00000650905(transcript)|go:"GO:0002238"(response to molecule of fungal origin)|go:"GO:0002269"(leukocyte activation involved in inflammatory response)|go:"GO:0002283"(neutrophil activation involved in immune response)|go:"GO:0002755"(MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0005121"(Toll binding)|go:"GO:0005123"(death receptor binding)|go:"GO:0005149"(interleukin-1 receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007254"(JNK cascade)|go:"GO:0008063"(Toll signaling pathway)|go:"GO:0009682"(induced systemic resistance)|go:"GO:0010008"(endosome membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032494"(response to peptidoglycan)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051607"(defense response to virus)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0070498"(interleukin-1-mediated signaling pathway)|go:"GO:0070555"(response to interleukin-1)|go:"GO:0070935"(3'-UTR-mediated mRNA stabilization)|go:"GO:0070944"(neutrophil-mediated killing of bacterium)|go:"GO:0070976"(TIR domain binding)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0090557"(establishment of endothelial intestinal barrier)|go:"GO:0140052"(cellular response to oxidised low-density lipoprotein particle stimulus)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:1900227"(positive regulation of NLRP3 inflammasome complex assembly)|go:"GO:0050830"(defense response to Gram-positive bacterium)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F	-	-	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:B920s5F0eUql/jtwlByyhI7ojGI9606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:A99FA2CF4B21A52A|rigid:9WjnDYl3V5Wej9V4AXAdqGwm5XY	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q99750	uniprotkb:Q12259	intact:EBI-724076|ensembl:ENSP00000230321|ensembl:ENSP00000362142	intact:EBI-30776|uniprotkb:D6VYA8|ensemblfungi:YLR108C	psi-mi:mdfi_human(display_long)|uniprotkb:Myogenic repressor I-mf(gene name synonym)|uniprotkb:MDFI(gene name)|psi-mi:MDFI(display_short)	psi-mi:yl108_yeast(display_long)|uniprotkb:L2913(orf name)|uniprotkb:YLR108C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553952|imex:IM-24995-4059	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005577.1|ensembl:ENSG00000112559(gene)|ensembl:ENST00000230321(transcript)|ensembl:ENST00000373051(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR026134|mint:Q99750|refseq:NP_001287733.1|refseq:NP_001287734.1|refseq:NP_001287735.1	refseq:NP_013209.1|sgd:S000004098|dip:DIP-4075N|ensemblfungi:YLR108C(gene)|ensemblfungi:YLR108C_mRNA(transcript)|go:"GO:0005634"(nucleus)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:V3vU0fihMOW18DMHAiDbuZ3asNU9606	rogid:CzknxXhhvgMp3J0/oi197EgZ05U559292	intact-crc:3035F5276907CCED|rigid:WRPqLXL2xvGWgfOHpP3Zau+273c	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q99750	uniprotkb:P42947	intact:EBI-724076|ensembl:ENSP00000230321|ensembl:ENSP00000362142	intact:EBI-26023|uniprotkb:D6VW77|ensemblfungi:YJL107C	psi-mi:mdfi_human(display_long)|uniprotkb:Myogenic repressor I-mf(gene name synonym)|uniprotkb:MDFI(gene name)|psi-mi:MDFI(display_short)	psi-mi:yjk7_yeast(display_long)|uniprotkb:J0813(orf name)|uniprotkb:YJL107C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553948|imex:IM-24995-4058	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005577.1|ensembl:ENSG00000112559(gene)|ensembl:ENST00000230321(transcript)|ensembl:ENST00000373051(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR026134|mint:Q99750|refseq:NP_001287733.1|refseq:NP_001287734.1|refseq:NP_001287735.1	sgd:S000003643|refseq:NP_012428.1|mint:P42947|dip:DIP-5095N|ensemblfungi:YJL107C(gene)|ensemblfungi:YJL107C_mRNA(transcript)|interpro:IPR010619(Protein of unknown function DUF1212)	-	-	crc64:D7659D1955F5677F	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:V3vU0fihMOW18DMHAiDbuZ3asNU9606	rogid:U2SdxE3xuNnsKGX/4Gb0dpB6M+w559292	intact-crc:5E7641EF3E49B7FB|rigid:SfauxaIjEe1YZMuZdEusbsmH1v8	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q99750	uniprotkb:Q12329	intact:EBI-724076|ensembl:ENSP00000230321|ensembl:ENSP00000362142	intact:EBI-8571|uniprotkb:D6VSF3|ensemblfungi:YDR171W	psi-mi:mdfi_human(display_long)|uniprotkb:Myogenic repressor I-mf(gene name synonym)|uniprotkb:MDFI(gene name)|psi-mi:MDFI(display_short)	psi-mi:hsp42_yeast(display_long)|uniprotkb:HSP42(gene name)|psi-mi:HSP42(display_short)|uniprotkb:YDR171W(locus name)|uniprotkb:YD9395.04(orf name)|uniprotkb:42 kDa heat shock protein(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553944|imex:IM-24995-4057	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005577.1|ensembl:ENSG00000112559(gene)|ensembl:ENST00000230321(transcript)|ensembl:ENST00000373051(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR026134|mint:Q99750|refseq:NP_001287733.1|refseq:NP_001287734.1|refseq:NP_001287735.1	refseq:NP_010456.1|sgd:S000002578|mint:Q12329|dip:DIP-2515N|ensemblfungi:YDR171W(gene)|ensemblfungi:YDR171W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0009408"(response to heat)|go:"GO:0009651"(response to salt stress)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043621"(protein self-association)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0140311"(protein sequestering activity)|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR031107	-	-	crc64:DF353A76493E3CE6	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:V3vU0fihMOW18DMHAiDbuZ3asNU9606	rogid:izvrv04fA3zcBqTeUeHD/erKGf4559292	intact-crc:1160E562597B4C41|rigid:1gAG+ma3vqbrFavwjVgrbasv7A8	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q99598	uniprotkb:P48606	intact:EBI-742638|intact:EBI-1050136|uniprotkb:B1APC6|refseq:NP_005990|dip:DIP-29463N	intact:EBI-18991|uniprotkb:D6W2W5|ensemblfungi:YOR265W	psi-mi:tsnax_human(display_long)|uniprotkb:Translin-associated factor X(gene name synonym)|uniprotkb:TSNAX(gene name)|psi-mi:TSNAX(display_short)|uniprotkb:TRAX(gene name synonym)	psi-mi:tbca_yeast(display_long)|uniprotkb:YOR265W(locus name)|uniprotkb:RBL2(gene name)|psi-mi:RBL2(display_short)|uniprotkb:Tubulin-folding cofactor A(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553920|imex:IM-24995-4051	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005634"(nucleus)|go:"GO:0008565"(obsolete protein transporter activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0007275"(multicellular organism development)|go:"GO:0007283"(spermatogenesis)|refseq:NP_005990.1|interpro:IPR002848(Translin)|interpro:IPR016068(Translin, N-terminal)|rcsb pdb:3PJA|rcsb pdb:3QB5|ensembl:ENST00000366639|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0031047"(gene silencing by RNA)|reactome:R-HSA-426486|go:"GO:0030422"(production of siRNA involved in RNA interference)|interpro:IPR036081|go:"GO:0003677"(DNA binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0046872"(metal ion binding)|go:"GO:0005829"(cytosol)|ensembl:ENSG00000116918|ensembl:ENSP00000355599|go:"GO:0005654"(nucleoplasm)|go:"GO:0003723"(RNA binding)|dip:DIP-29463N|mint:MINT-1347706|go:"GO:0044822"|interpro:IPR016069(Translin, C-terminal)|go:"GO:0031687"(A2A adenosine receptor binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0003697"(single-stranded DNA binding)	ensemblfungi:YOR265W(gene)|ensemblfungi:YOR265W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:0007023"(post-chaperonin tubulin folding pathway)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0015631"(tubulin binding)|go:"GO:0048487"(beta-tubulin binding)|interpro:IPR004226(Tubulin binding cofactor A)|interpro:IPR036126|rcsb pdb:1QSD|refseq:NP_014908.1|sgd:S000005791|dip:DIP-4101N|mint:P48606	-	crc64:D38B0DD96B50C0B9|no-uniprot-update:|caution:"The protein could not be merged with EBI-12908040 because of some conflicts with the protein sequence (features which cannot be shifted)."	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:TaNIxjLHGusdq32WbdJ21DG9yBQ9606	rogid:Qbjv1Un+CKyQZ+gTbJl7ETlkc9o559292	intact-crc:14841DFDE62EC736|rigid:SmxS0R0ePAiBfY3hx6PXEYderCQ	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q99750	uniprotkb:P06782	intact:EBI-724076|ensembl:ENSP00000230321|ensembl:ENSP00000362142	intact:EBI-17516|uniprotkb:D6VTA0|ensemblfungi:YDR477W	psi-mi:mdfi_human(display_long)|uniprotkb:Myogenic repressor I-mf(gene name synonym)|uniprotkb:MDFI(gene name)|psi-mi:MDFI(display_short)	psi-mi:snf1_yeast(display_long)|uniprotkb:SNF1(gene name)|psi-mi:SNF1(display_short)|uniprotkb:CAT1(gene name synonym)|uniprotkb:CCR1(gene name synonym)|uniprotkb:GLC2(gene name synonym)|uniprotkb:PAS14(gene name synonym)|uniprotkb:Sucrose nonfermentating protein 1(gene name synonym)|uniprotkb:D8035.20(orf name)|uniprotkb:YDR477W(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553936|imex:IM-24995-4055	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005577.1|ensembl:ENSG00000112559(gene)|ensembl:ENST00000230321(transcript)|ensembl:ENST00000373051(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR026134|mint:Q99750|refseq:NP_001287733.1|refseq:NP_001287734.1|refseq:NP_001287735.1	refseq:NP_010765.3|sgd:S000002885|ensemblfungi:YDR477W(gene)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0071940"(fungal-type cell wall assembly)|go:"GO:0090606"(single-species surface biofilm formation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900436"(positive regulation of filamentous growth of a population of unicellular organisms in response to starvation)|go:"GO:2000222"(positive regulation of pseudohyphal growth)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013896(Ubiquitin-associated region 2)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR028375|interpro:IPR032270|rcsb pdb:2FH9|rcsb pdb:2QLV|rcsb pdb:3DAE|rcsb pdb:3HYH|rcsb pdb:3MN3|rcsb pdb:3T4N|rcsb pdb:3TDH|rcsb pdb:3TE5|reactome:R-SCE-1632852|reactome:R-SCE-163680|reactome:R-SCE-200425|reactome:R-SCE-380972|ensemblfungi:YDR477W_mRNA(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000144"(cellular bud neck septin ring)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004679"(AMP-activated protein kinase activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005641"(nuclear envelope lumen)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0007155"(cell adhesion)|go:"GO:0016239"(positive regulation of macroautophagy)|dip:DIP-18N|mint:P06782	-	-	crc64:F5C63565C986C4E3	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:V3vU0fihMOW18DMHAiDbuZ3asNU9606	rogid:O/SAW1kJE3fpoXPHGLG01i9RePs559292	intact-crc:881F8AC7B823C0B5|rigid:cSDwEv05Wb9pdoi2U44eYzMbaHM	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q99750	uniprotkb:P32589	intact:EBI-724076|ensembl:ENSP00000230321|ensembl:ENSP00000362142	intact:EBI-8648|uniprotkb:D6W3R1|ensemblfungi:YPL106C	psi-mi:mdfi_human(display_long)|uniprotkb:Myogenic repressor I-mf(gene name synonym)|uniprotkb:MDFI(gene name)|psi-mi:MDFI(display_short)	psi-mi:hsp7f_yeast(display_long)|uniprotkb:SSE1(gene name)|psi-mi:SSE1(display_short)|uniprotkb:MSI3(gene name synonym)|uniprotkb:YPL106C(locus name)|uniprotkb:LPG3C(orf name)|uniprotkb:Chaperone protein MSI3(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553932|imex:IM-24995-4054	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005577.1|ensembl:ENSG00000112559(gene)|ensembl:ENST00000230321(transcript)|ensembl:ENST00000373051(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR026134|mint:Q99750|refseq:NP_001287733.1|refseq:NP_001287734.1|refseq:NP_001287735.1	refseq:NP_015219.1|sgd:S000006027|mint:P32589|dip:DIP-6645N|ensemblfungi:YPL106C(gene)|ensemblfungi:YPL106C_mRNA(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0006457"(protein folding)|go:"GO:0006914"(autophagy)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0042026"(protein refolding)|go:"GO:0042277"(peptide binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|rcsb pdb:2QXL|rcsb pdb:3C7N|rcsb pdb:3D2E|rcsb pdb:3D2F	-	-	crc64:6558259111B0BC38	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:V3vU0fihMOW18DMHAiDbuZ3asNU9606	rogid:16yTg05haoflKGNZTW4EqC7FSs0559292	intact-crc:01EBD69AA0C6FE1D|rigid:p5E3oQwlivMCNoDUDVqTwze95nY	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P35184	uniprotkb:Q99750	intact:EBI-17971|uniprotkb:D6VVU2|ensemblfungi:YIR012W	intact:EBI-724076|ensembl:ENSP00000230321|ensembl:ENSP00000362142	psi-mi:sqt1_yeast(display_long)|uniprotkb:YIB12W(orf name)|uniprotkb:YIR012W(locus name)|uniprotkb:SQT1(gene name)|psi-mi:SQT1(display_short)	psi-mi:mdfi_human(display_long)|uniprotkb:Myogenic repressor I-mf(gene name synonym)|uniprotkb:MDFI(gene name)|psi-mi:MDFI(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553928|imex:IM-24995-4053	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012277.1|sgd:S000001451|ensemblfungi:YIR012W_mRNA(transcript)|ensemblfungi:YIR012W(gene)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|rcsb pdb:4ZOV|rcsb pdb:4ZOX|rcsb pdb:5AMS|dip:DIP-2508N|mint:P35184	refseq:NP_005577.1|ensembl:ENSG00000112559(gene)|ensembl:ENST00000230321(transcript)|ensembl:ENST00000373051(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR026134|mint:Q99750|refseq:NP_001287733.1|refseq:NP_001287734.1|refseq:NP_001287735.1	-	crc64:981D566076B0C881	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:u/Q5uAjR85ZD3op0nHiN20IVCLY559292	rogid:V3vU0fihMOW18DMHAiDbuZ3asNU9606	intact-crc:0B663BE4463E4965|rigid:m98TxjikmR5tLdYm+xJ8H80jw/s	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q99614	uniprotkb:Q05899	intact:EBI-742074|uniprotkb:Q9BVT3|uniprotkb:B2RCT2|uniprotkb:D3DQJ8|ensembl:ENSP00000231238|ensembl:ENSP00000429225|ensembl:ENSP00000507891	intact:EBI-33462|uniprotkb:D6VYU1|ensemblfungi:YLR297W	psi-mi:ttc1_human(display_long)|uniprotkb:TTC1(gene name)|psi-mi:TTC1(display_short)|uniprotkb:TPR1(gene name synonym)	psi-mi:yl297_yeast(display_long)|uniprotkb:YLR297W(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553924|imex:IM-24995-4052	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001269429.1|refseq:NP_003305.1|ensembl:ENST00000231238(transcript)|ensembl:ENST00000522793(transcript)|ensembl:ENST00000682719(transcript)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|ensembl:ENSG00000113312(gene)	sgd:S000004288|refseq:NP_013400.1|dip:DIP-4684N|ensemblfungi:YLR297W(gene)|ensemblfungi:YLR297W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016021"(integral component of membrane)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:jpDASWCrto0zMhBm3Cj9aDQURm09606	rogid:5NnJTt1UJw0+xxbJS5roF36sLGI559292	intact-crc:6B3C7ABDA90CB23C|rigid:EBQypxPb9QJrQeke+M9gnc/IFBo	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q99750	uniprotkb:P34164	intact:EBI-724076|ensembl:ENSP00000230321|ensembl:ENSP00000362142	intact:EBI-17187|uniprotkb:D6VTU7|ensemblfungi:YGL208W	psi-mi:mdfi_human(display_long)|uniprotkb:Myogenic repressor I-mf(gene name synonym)|uniprotkb:MDFI(gene name)|psi-mi:MDFI(display_short)	psi-mi:sip2_yeast(display_long)|uniprotkb:SIP2(gene name)|psi-mi:SIP2(display_short)|uniprotkb:SPM2(gene name synonym)|uniprotkb:YGL208W(locus name)|uniprotkb:G1155(orf name)|uniprotkb:Protein SPM2(gene name synonym)|uniprotkb:SNF1-interacting protein 2(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553940|imex:IM-24995-4056	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005577.1|ensembl:ENSG00000112559(gene)|ensembl:ENST00000230321(transcript)|ensembl:ENST00000373051(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR026134|mint:Q99750|refseq:NP_001287733.1|refseq:NP_001287734.1|refseq:NP_001287735.1	refseq:NP_011307.1|sgd:S000003176|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0080090"(regulation of primary metabolic process)|go:"GO:2000222"(positive regulation of pseudohyphal growth)|interpro:IPR006828(5-AMP-activated protein kinase, beta subunit, complex-interacting region)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030077|interpro:IPR032640|interpro:IPR037256|rcsb pdb:2QLV|rcsb pdb:3T4N|rcsb pdb:3TDH|rcsb pdb:3TE5|reactome:R-SCE-1632852|reactome:R-SCE-380972|go:"GO:0043254"(regulation of protein-containing complex assembly)|ensemblfungi:YGL208W(gene)|ensemblfungi:YGL208W_mRNA(transcript)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0042149"(cellular response to glucose starvation)|dip:DIP-865N|mint:P34164	-	-	crc64:CBB4FCE0070A563F	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:V3vU0fihMOW18DMHAiDbuZ3asNU9606	rogid:KBJuNhrNAHm6B0INUd1UIiASmok559292	intact-crc:9D8B6F93C6392108|rigid:lVjeUXAAI3amze6bCE5iNeVAqCk	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9BQC3	uniprotkb:P40487	intact:EBI-10237931|uniprotkb:O60623|uniprotkb:B4DNI8|uniprotkb:B2RDE3|uniprotkb:A8MVC9|ensembl:ENSP00000255108	intact:EBI-25162|uniprotkb:D6VVI4|ensemblfungi:YIL103W	psi-mi:dph2_human(display_long)|uniprotkb:Diphthamide biosynthesis protein 2(gene name synonym)|uniprotkb:Diphtheria toxin resistance protein 2(gene name synonym)|uniprotkb:DPH2(gene name)|psi-mi:DPH2(display_short)|uniprotkb:DPH2L2(gene name synonym)|uniprotkb:"S-adenosyl-L-methionine:L-histidine 3-amino-3-carboxypropyltransferase 2"(gene name synonym)	psi-mi:dph1_yeast(display_long)|uniprotkb:DPH1(gene name)|psi-mi:DPH1(display_short)|uniprotkb:Diphthamide biosynthesis protein 1(gene name synonym)|uniprotkb:Diphtheria toxin resistance protein 1(gene name synonym)|uniprotkb:"S-adenosyl-L-methionine:L-histidine 3-amino-3-carboxypropyltransferase 1"(gene name synonym)|uniprotkb:YIL103W(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553984|imex:IM-24995-4067	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306095.1|refseq:NP_001306098.1|refseq:NP_001034678.1|refseq:NP_001375.2|ensembl:ENSG00000132768(gene)|ensembl:ENST00000255108(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0017183"(peptidyl-diphthamide biosynthetic process from peptidyl-histidine)|go:"GO:0090560"("2-(3-amino-3-carboxypropyl)histidine synthase activity")|interpro:IPR010014(Diphthamide synthesis, DHP2)|interpro:IPR016435(Diphthamide synthesis, DHP1)|interpro:IPR042263|interpro:IPR042265|reactome:R-HSA-5358493	refseq:NP_012163.1|sgd:S000001365|mint:P40487|dip:DIP-5653N|ensemblfungi:YIL103W(gene)|ensemblfungi:YIL103W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0017183"(peptidyl-diphthamide biosynthetic process from peptidyl-histidine)|go:"GO:0090560"("2-(3-amino-3-carboxypropyl)histidine synthase activity")|interpro:IPR016435(Diphthamide synthesis, DHP1)|interpro:IPR035435|interpro:IPR042263|interpro:IPR042264|interpro:IPR042265|reactome:R-SCE-5358493	-	-	crc64:22E93852E03C6722	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:/Z9UhAa8qkHe3rPFS3OPfiJ4RFM9606	rogid:zk1Esuvz7u5GtymKbFzfv+PFAPQ559292	intact-crc:16729CC7FAB74691|rigid:2KWZtj6bcqiQy22WKS9+Eu5pQSw	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9BQC3	uniprotkb:P32502	intact:EBI-10237931|uniprotkb:O60623|uniprotkb:B4DNI8|uniprotkb:B2RDE3|uniprotkb:A8MVC9|ensembl:ENSP00000255108	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:dph2_human(display_long)|uniprotkb:Diphthamide biosynthesis protein 2(gene name synonym)|uniprotkb:Diphtheria toxin resistance protein 2(gene name synonym)|uniprotkb:DPH2(gene name)|psi-mi:DPH2(display_short)|uniprotkb:DPH2L2(gene name synonym)|uniprotkb:"S-adenosyl-L-methionine:L-histidine 3-amino-3-carboxypropyltransferase 2"(gene name synonym)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553980|imex:IM-24995-4066	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306095.1|refseq:NP_001306098.1|refseq:NP_001034678.1|refseq:NP_001375.2|ensembl:ENSG00000132768(gene)|ensembl:ENST00000255108(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0017183"(peptidyl-diphthamide biosynthetic process from peptidyl-histidine)|go:"GO:0090560"("2-(3-amino-3-carboxypropyl)histidine synthase activity")|interpro:IPR010014(Diphthamide synthesis, DHP2)|interpro:IPR016435(Diphthamide synthesis, DHP1)|interpro:IPR042263|interpro:IPR042265|reactome:R-HSA-5358493	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731	-	-	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:/Z9UhAa8qkHe3rPFS3OPfiJ4RFM9606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:FDFDA736A682776D|rigid:nG0On3X0/CoAisHrSzA34Kvk14s	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P34164	uniprotkb:Q9BQ66	intact:EBI-17187|uniprotkb:D6VTU7|ensemblfungi:YGL208W	intact:EBI-739863|uniprotkb:A3KMC5|uniprotkb:Q495I0|ensembl:ENSP00000377582|ensembl:ENSP00000458979	psi-mi:sip2_yeast(display_long)|uniprotkb:SIP2(gene name)|psi-mi:SIP2(display_short)|uniprotkb:SPM2(gene name synonym)|uniprotkb:YGL208W(locus name)|uniprotkb:G1155(orf name)|uniprotkb:Protein SPM2(gene name synonym)|uniprotkb:SNF1-interacting protein 2(gene name synonym)	psi-mi:kr412_human(display_long)|uniprotkb:KRTAP4-12(gene name)|psi-mi:KRTAP4-12(display_short)|uniprotkb:KAP4.12(gene name synonym)|uniprotkb:KRTAP4.12(gene name synonym)|uniprotkb:Keratin-associated protein 4.12(gene name synonym)|uniprotkb:Ultrahigh sulfur keratin-associated protein 4.12(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553976|imex:IM-24995-4065	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011307.1|sgd:S000003176|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0080090"(regulation of primary metabolic process)|go:"GO:2000222"(positive regulation of pseudohyphal growth)|interpro:IPR006828(5-AMP-activated protein kinase, beta subunit, complex-interacting region)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030077|interpro:IPR032640|interpro:IPR037256|rcsb pdb:2QLV|rcsb pdb:3T4N|rcsb pdb:3TDH|rcsb pdb:3TE5|reactome:R-SCE-1632852|reactome:R-SCE-380972|go:"GO:0043254"(regulation of protein-containing complex assembly)|ensemblfungi:YGL208W(gene)|ensemblfungi:YGL208W_mRNA(transcript)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0042149"(cellular response to glucose starvation)|dip:DIP-865N|mint:P34164	refseq:NP_114060.1|ensembl:ENSG00000213416(gene)|ensembl:ENSG00000263236(gene)|ensembl:ENST00000394014(transcript)|ensembl:ENST00000571271(transcript)|go:"GO:0045095"(keratin filament)|interpro:IPR002494(Keratin, high sulphur B2 protein)	-	crc64:CBB4FCE0070A563F	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:KBJuNhrNAHm6B0INUd1UIiASmok559292	rogid:XLiYOwNd549kn287BJWgx5zmDCY9606	intact-crc:C732EE51705DD284|rigid:hJwboUKLqAXxX4FMOLJNHYPWlWM	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q99942	uniprotkb:P38340	intact:EBI-348482|ensembl:ENSP00000364235|ensembl:ENSP00000387879|ensembl:ENSP00000388795|ensembl:ENSP00000401172|ensembl:ENSP00000413131|ensembl:ENSP00000415127|ensembl:ENSP00000415784|uniprotkb:A2BFI6|uniprotkb:Q0VDB7|uniprotkb:Q9UMQ2|uniprotkb:B2R4K3	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:rnf5_human(display_long)|uniprotkb:RNF5(gene name)|psi-mi:RNF5(display_short)|uniprotkb:G16(gene name synonym)|uniprotkb:RING finger protein 5(gene name synonym)|uniprotkb:Protein G16(gene name synonym)|uniprotkb:NG2(gene name synonym)|uniprotkb:RMA1(gene name synonym)|uniprotkb:Ram1 homolog(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF5(gene name synonym)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553960|imex:IM-24995-4061	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_008844.1|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009617"(response to bacterium)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031648"(protein destabilization)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0036503"(ERAD pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0044257"(cellular protein catabolic process)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0044390"(ubiquitin-like protein conjugating enzyme binding)|ensembl:ENST00000456167(transcript)|ensembl:ENSG00000183574(gene)|ensembl:ENSG00000204308(gene)|ensembl:ENSG00000223767(gene)|ensembl:ENSG00000225452(gene)|ensembl:ENSG00000227277(gene)|ensembl:ENSG00000228405(gene)|ensembl:ENSG00000228907(gene)|ensembl:ENST00000375094(transcript)|ensembl:ENST00000413786(transcript)|ensembl:ENST00000432616(transcript)|ensembl:ENST00000445885(transcript)|ensembl:ENST00000449794(transcript)|ensembl:ENST00000453473(transcript)|go:"GO:0055085"(transmembrane transport)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|go:"GO:2000785"(regulation of autophagosome assembly)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|reactome:R-HSA-382556|reactome:R-HSA-5678895|reactome:R-HSA-901032|go:"GO:0044877"(protein-containing complex binding)|dip:DIP-29268N	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F	-	-	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:eHlCD+xbWmpzFdhVn6OC5MPqeNE9606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:04E9B324C32A74C4|rigid:wnWWHJark3LiQ8F96socQHho5FA	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P38340	uniprotkb:Q9BPX1	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-742664|uniprotkb:Q9UKU3|ensembl:ENSP00000263278	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:dhb14_human(display_long)|uniprotkb:DHRS10(gene name synonym)|uniprotkb:Dehydrogenase/reductase SDR family member 10(gene name synonym)|uniprotkb:17-beta-hydroxysteroid dehydrogenase DHRS10(gene name synonym)|uniprotkb:Retinal short-chain dehydrogenase/reductase retSDR3(gene name synonym)|uniprotkb:HSD17B14(gene name)|psi-mi:HSD17B14(display_short)|uniprotkb:SDR3(gene name synonym)|uniprotkb:SDR47C1(gene name synonym)|uniprotkb:Short chain dehydrogenase/reductase family 47C member 1(gene name synonym)|uniprotkb:UNQ502/PRO474(orf name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553968|imex:IM-24995-4063	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F	refseq:NP_057330.2|ensembl:ENSG00000087076(gene)|ensembl:ENST00000263278(transcript)|go:"GO:0004303"(estradiol 17-beta-dehydrogenase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006706"(steroid catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0044594"("17-beta-hydroxysteroid dehydrogenase (NAD+) activity")|go:"GO:0047045"("testosterone 17-beta-dehydrogenase (NADP+) activity")|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR020904|interpro:IPR036291|rcsb pdb:1YDE|rcsb pdb:5EN4|rcsb pdb:5HS6|rcsb pdb:5ICM|rcsb pdb:5ICS|rcsb pdb:5JS6|rcsb pdb:5JSF|rcsb pdb:5L7T|rcsb pdb:5L7W|rcsb pdb:5L7Y|rcsb pdb:5O42|rcsb pdb:5O43|rcsb pdb:5O6O|rcsb pdb:5O6X|rcsb pdb:5O6Z|rcsb pdb:5O72|rcsb pdb:5O7C|rcsb pdb:6EMM|rcsb pdb:6FFB|rcsb pdb:6G4L|rcsb pdb:6GBT|rcsb pdb:6GTB|rcsb pdb:6GTU|rcsb pdb:6H0M|rcsb pdb:6HNO|rcsb pdb:6QCK|rcsb pdb:6ZDE|rcsb pdb:6ZDI|reactome:R-HSA-193144	-	crc64:66699F37B0013088	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:/t03kHO/EWlqKNv7+TkWbTV9jpM9606	intact-crc:8822D04838AD7E6E|rigid:YpBKWwGDzxQyIyVR8BXnGsfOtRo	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9BPX1	uniprotkb:P32502	intact:EBI-742664|uniprotkb:Q9UKU3|ensembl:ENSP00000263278	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:dhb14_human(display_long)|uniprotkb:DHRS10(gene name synonym)|uniprotkb:Dehydrogenase/reductase SDR family member 10(gene name synonym)|uniprotkb:17-beta-hydroxysteroid dehydrogenase DHRS10(gene name synonym)|uniprotkb:Retinal short-chain dehydrogenase/reductase retSDR3(gene name synonym)|uniprotkb:HSD17B14(gene name)|psi-mi:HSD17B14(display_short)|uniprotkb:SDR3(gene name synonym)|uniprotkb:SDR47C1(gene name synonym)|uniprotkb:Short chain dehydrogenase/reductase family 47C member 1(gene name synonym)|uniprotkb:UNQ502/PRO474(orf name)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553964|imex:IM-24995-4062	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_057330.2|ensembl:ENSG00000087076(gene)|ensembl:ENST00000263278(transcript)|go:"GO:0004303"(estradiol 17-beta-dehydrogenase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006706"(steroid catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0044594"("17-beta-hydroxysteroid dehydrogenase (NAD+) activity")|go:"GO:0047045"("testosterone 17-beta-dehydrogenase (NADP+) activity")|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR020904|interpro:IPR036291|rcsb pdb:1YDE|rcsb pdb:5EN4|rcsb pdb:5HS6|rcsb pdb:5ICM|rcsb pdb:5ICS|rcsb pdb:5JS6|rcsb pdb:5JSF|rcsb pdb:5L7T|rcsb pdb:5L7W|rcsb pdb:5L7Y|rcsb pdb:5O42|rcsb pdb:5O43|rcsb pdb:5O6O|rcsb pdb:5O6X|rcsb pdb:5O6Z|rcsb pdb:5O72|rcsb pdb:5O7C|rcsb pdb:6EMM|rcsb pdb:6FFB|rcsb pdb:6G4L|rcsb pdb:6GBT|rcsb pdb:6GTB|rcsb pdb:6GTU|rcsb pdb:6H0M|rcsb pdb:6HNO|rcsb pdb:6QCK|rcsb pdb:6ZDE|rcsb pdb:6ZDI|reactome:R-HSA-193144	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731	-	-	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:/t03kHO/EWlqKNv7+TkWbTV9jpM9606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:148CDB428770F1C5|rigid:vs25FILt8u/ffJMBLpyvWk9P8Cs	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P06782	uniprotkb:Q9BQ66	intact:EBI-17516|uniprotkb:D6VTA0|ensemblfungi:YDR477W	intact:EBI-739863|uniprotkb:A3KMC5|uniprotkb:Q495I0|ensembl:ENSP00000377582|ensembl:ENSP00000458979	psi-mi:snf1_yeast(display_long)|uniprotkb:SNF1(gene name)|psi-mi:SNF1(display_short)|uniprotkb:CAT1(gene name synonym)|uniprotkb:CCR1(gene name synonym)|uniprotkb:GLC2(gene name synonym)|uniprotkb:PAS14(gene name synonym)|uniprotkb:Sucrose nonfermentating protein 1(gene name synonym)|uniprotkb:D8035.20(orf name)|uniprotkb:YDR477W(locus name)	psi-mi:kr412_human(display_long)|uniprotkb:KRTAP4-12(gene name)|psi-mi:KRTAP4-12(display_short)|uniprotkb:KAP4.12(gene name synonym)|uniprotkb:KRTAP4.12(gene name synonym)|uniprotkb:Keratin-associated protein 4.12(gene name synonym)|uniprotkb:Ultrahigh sulfur keratin-associated protein 4.12(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553972|imex:IM-24995-4064	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010765.3|sgd:S000002885|ensemblfungi:YDR477W(gene)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0071940"(fungal-type cell wall assembly)|go:"GO:0090606"(single-species surface biofilm formation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900436"(positive regulation of filamentous growth of a population of unicellular organisms in response to starvation)|go:"GO:2000222"(positive regulation of pseudohyphal growth)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013896(Ubiquitin-associated region 2)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR028375|interpro:IPR032270|rcsb pdb:2FH9|rcsb pdb:2QLV|rcsb pdb:3DAE|rcsb pdb:3HYH|rcsb pdb:3MN3|rcsb pdb:3T4N|rcsb pdb:3TDH|rcsb pdb:3TE5|reactome:R-SCE-1632852|reactome:R-SCE-163680|reactome:R-SCE-200425|reactome:R-SCE-380972|ensemblfungi:YDR477W_mRNA(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000144"(cellular bud neck septin ring)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004679"(AMP-activated protein kinase activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005641"(nuclear envelope lumen)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0007155"(cell adhesion)|go:"GO:0016239"(positive regulation of macroautophagy)|dip:DIP-18N|mint:P06782	refseq:NP_114060.1|ensembl:ENSG00000213416(gene)|ensembl:ENSG00000263236(gene)|ensembl:ENST00000394014(transcript)|ensembl:ENST00000571271(transcript)|go:"GO:0045095"(keratin filament)|interpro:IPR002494(Keratin, high sulphur B2 protein)	-	crc64:F5C63565C986C4E3	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:O/SAW1kJE3fpoXPHGLG01i9RePs559292	rogid:XLiYOwNd549kn287BJWgx5zmDCY9606	intact-crc:2DEB5EB90A2C1379|rigid:aFoJnKS6fhMQMaDuej7AMRvcy2c	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9BQY4	uniprotkb:Q03373	intact:EBI-372094|uniprotkb:Q9BR00|ensembl:ENSP00000360441	intact:EBI-34019|uniprotkb:D6VTA3|ensemblfungi:YDR480W	psi-mi:rhxf2_human(display_long)|uniprotkb:RHOXF2(gene name)|psi-mi:RHOXF2(display_short)|uniprotkb:THG1(gene name synonym)|uniprotkb:Paired-like homeobox protein PEPP-2(gene name synonym)|uniprotkb:Testis homeobox gene 1(gene name synonym)|uniprotkb:PEPP2(gene name synonym)	psi-mi:dig2_yeast(display_long)|uniprotkb:DIG2(gene name)|psi-mi:DIG2(display_short)|uniprotkb:Regulator of sterile twelve 2(gene name synonym)|uniprotkb:Regulator of STE12 protein 2(gene name synonym)|uniprotkb:RST2(gene name synonym)|uniprotkb:D8035.23(orf name)|uniprotkb:YDR480W(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554004|imex:IM-24995-4072	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_115887.1|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0042802"(identical protein binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|ensembl:ENSG00000131721(gene)|ensembl:ENST00000371388(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)	sgd:S000002888|refseq:NP_010768.1|mint:Q03373|dip:DIP-1292N|ensemblfungi:YDR480W(gene)|ensemblfungi:YDR480W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0008134"(transcription factor binding)|go:"GO:0046020"(negative regulation of transcription from RNA polymerase II promoter by pheromones)|go:"GO:1990526"(Ste12p-Dig1p-Dig2p complex)|go:"GO:2000218"(negative regulation of invasive growth in response to glucose limitation)|go:"GO:2000221"(negative regulation of pseudohyphal growth)	-	-	crc64:8E71278ED6D3A912	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:shpgPqf80gNt+gFDv1K+827ELUQ9606	rogid:Uh6OsQDXtmnLKMAEZHl/NTKCEYY559292	intact-crc:A70D7A16D7A06791|rigid:fsCVKuQevcaXnW0lHqXZOKF+bPI	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P40956	uniprotkb:Q9BQY4	intact:EBI-7968|uniprotkb:D6VTX2|ensemblfungi:YGL181W	intact:EBI-372094|uniprotkb:Q9BR00|ensembl:ENSP00000360441	psi-mi:gts1_yeast(display_long)|uniprotkb:YGL181W(locus name)|uniprotkb:GTS1(gene name)|psi-mi:GTS1(display_short)|uniprotkb:LSR1(gene name synonym)|uniprotkb:Protein LSR1(gene name synonym)	psi-mi:rhxf2_human(display_long)|uniprotkb:RHOXF2(gene name)|psi-mi:RHOXF2(display_short)|uniprotkb:THG1(gene name synonym)|uniprotkb:Paired-like homeobox protein PEPP-2(gene name synonym)|uniprotkb:Testis homeobox gene 1(gene name synonym)|uniprotkb:PEPP2(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554000|imex:IM-24995-4071	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011334.1|sgd:S000003149|mint:P40956|dip:DIP-2746N|ensemblfungi:YGL181W(gene)|ensemblfungi:YGL181W_mRNA(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0006897"(endocytosis)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010512"(negative regulation of phosphatidylinositol biosynthetic process)|go:"GO:0030479"(actin cortical patch)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR037278|interpro:IPR038508	refseq:NP_115887.1|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0042802"(identical protein binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|ensembl:ENSG00000131721(gene)|ensembl:ENST00000371388(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)	-	crc64:D687E3BF6B620795	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:8kgpssCRrHiTHsFaOH2nDK6EIjk559292	rogid:shpgPqf80gNt+gFDv1K+827ELUQ9606	intact-crc:C933063652106D3A|rigid:RFaTOGL6SABsauK/jjDGC+NhWAY	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P53829	uniprotkb:Q9BQY4	intact:EBI-28306|uniprotkb:D6W0Q5|ensemblfungi:YNL288W	intact:EBI-372094|uniprotkb:Q9BR00|ensembl:ENSP00000360441	psi-mi:caf40_yeast(display_long)|uniprotkb:YNL288W(locus name)|uniprotkb:N0540(orf name)|uniprotkb:40 kDa CCR4-associated factor(gene name synonym)|uniprotkb:CAF40(gene name)|psi-mi:CAF40(display_short)	psi-mi:rhxf2_human(display_long)|uniprotkb:RHOXF2(gene name)|psi-mi:RHOXF2(display_short)|uniprotkb:THG1(gene name synonym)|uniprotkb:Paired-like homeobox protein PEPP-2(gene name synonym)|uniprotkb:Testis homeobox gene 1(gene name synonym)|uniprotkb:PEPP2(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553996|imex:IM-24995-4070	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014111.1|sgd:S000005232|dip:DIP-1995N|mint:P53829|ensemblfungi:YNL288W(gene)|ensemblfungi:YNL288W_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR007216(Cell differentiation, Rcd1-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:4CV5	refseq:NP_115887.1|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0042802"(identical protein binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|ensembl:ENSG00000131721(gene)|ensembl:ENST00000371388(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)	-	crc64:F3DBABE6AD3C7F3C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:etuSSgFGQOcgxPDexEXUqQg6H5s559292	rogid:shpgPqf80gNt+gFDv1K+827ELUQ9606	intact-crc:2FA68C5750F64805|rigid:cr3njtD9XOdDhbJXnJOvYX9vN0Q	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P32502	uniprotkb:Q9BQD3	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	intact:EBI-739657|uniprotkb:O76098|ensembl:ENSP00000472678|ensembl:ENSP00000472836|ensembl:ENSP00000222307|ensembl:ENSP00000438903|ensembl:ENSP00000443549|ensembl:ENSP00000468990|ensembl:ENSP00000471554	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:kxdl1_human(display_long)|uniprotkb:KXD1(gene name)|psi-mi:KXD1(display_short)|uniprotkb:C19orf50(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553992|imex:IM-24995-4069	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731	refseq:NP_001165419.1|refseq:NP_001165420.1|refseq:NP_076974.2|ensembl:ENST00000222307(transcript)|ensembl:ENST00000539106(transcript)|ensembl:ENST00000540691(transcript)|ensembl:ENST00000595073(transcript)|ensembl:ENST00000599319(transcript)|ensembl:ENST00000600654(transcript)|ensembl:ENST00000602094(transcript)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0032418"(lysosome localization)|go:"GO:0099078"(BORC complex)|interpro:IPR019371|interpro:IPR039843|ensembl:ENSG00000105700(gene)|refseq:XP_016882770.1|refseq:XP_011526574.1|refseq:XP_011526575.1|refseq:XP_006722946.1	-	crc64:A5409FAF1594854C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	rogid:5BoR6AN0Ywb1eI04Rw4chmlWVI09606	intact-crc:63EF28444D478AD5|rigid:/PHNZMGCVLir4/q0DlagUS4LjNQ	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9BQD3	uniprotkb:P40368	intact:EBI-739657|uniprotkb:O76098|ensembl:ENSP00000472678|ensembl:ENSP00000472836|ensembl:ENSP00000222307|ensembl:ENSP00000438903|ensembl:ENSP00000443549|ensembl:ENSP00000468990|ensembl:ENSP00000471554	intact:EBI-12331|ensemblfungi:YJL061W|uniprotkb:D6VWC1	psi-mi:kxdl1_human(display_long)|uniprotkb:KXD1(gene name)|psi-mi:KXD1(display_short)|uniprotkb:C19orf50(gene name synonym)	psi-mi:nup82_yeast(display_long)|uniprotkb:NUP82(gene name)|psi-mi:NUP82(display_short)|uniprotkb:YJL061W(locus name)|uniprotkb:J1135(orf name)|uniprotkb:HRB187(orf name)|uniprotkb:Nuclear pore protein NUP82(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11553988|imex:IM-24995-4068	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001165419.1|refseq:NP_001165420.1|refseq:NP_076974.2|ensembl:ENST00000222307(transcript)|ensembl:ENST00000539106(transcript)|ensembl:ENST00000540691(transcript)|ensembl:ENST00000595073(transcript)|ensembl:ENST00000599319(transcript)|ensembl:ENST00000600654(transcript)|ensembl:ENST00000602094(transcript)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0032418"(lysosome localization)|go:"GO:0099078"(BORC complex)|interpro:IPR019371|interpro:IPR039843|ensembl:ENSG00000105700(gene)|refseq:XP_016882770.1|refseq:XP_011526574.1|refseq:XP_011526575.1|refseq:XP_006722946.1	refseq:NP_012474.1|sgd:S000003597|ensemblfungi:YJL061W(gene)|ensemblfungi:YJL061W_mRNA(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0005634"(nucleus)|interpro:IPR037700|rcsb pdb:3PBP|rcsb pdb:3TKN|go:"GO:0005643"(nuclear pore)|go:"GO:0005829"(cytosol)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0044612"(nuclear pore linkers)|go:"GO:0044614"(nuclear pore cytoplasmic filaments)|mint:P40368|dip:DIP-913N	-	-	crc64:C379B5E111E26B50	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:5BoR6AN0Ywb1eI04Rw4chmlWVI09606	rogid:g1+jqOMmde8phrNI9H7nFlXwjH0559292	intact-crc:22297BDD37F6B904|rigid:z+3r6dsLXpSeZpn1SwXxTO88OOM	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9BQY9-2	uniprotkb:P25651	intact:EBI-11524759|ensembl:ENSP00000349822|ensembl:ENSP00000354250|ensembl:ENSP00000361795|ensembl:ENSP00000361797|ensembl:ENSP00000361808	intact:EBI-22001|uniprotkb:D6VR86|ensemblfungi:YCR086W	psi-mi:q9bqy9-2(display_long)|uniprotkb:DBNDD2(gene name)|psi-mi:DBNDD2(display_short)|uniprotkb:C20orf35(gene name synonym)|uniprotkb:Casein kinase-1 binding protein(gene name synonym)|uniprotkb:HSMNP1(gene name synonym)	psi-mi:csm1_yeast(display_long)|uniprotkb:YCR086W(locus name)|uniprotkb:YCR86W(orf name)|uniprotkb:Chromosome segregation in meiosis protein 1(gene name synonym)|uniprotkb:CSM1(gene name)|psi-mi:CSM1(display_short)|uniprotkb:SPO86(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554008|imex:IM-24995-4073	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-747462(isoform-parent)|ensembl:ENSG00000244274(gene)|ensembl:ENST00000357275(transcript)|ensembl:ENST00000360981(transcript)|ensembl:ENST00000372710(transcript)|ensembl:ENST00000372712(transcript)|ensembl:ENST00000372723(transcript)	refseq:NP_010009.1|sgd:S000000682|dip:DIP-1283N|ensemblfungi:YCR086W(gene)|ensemblfungi:YCR086W_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005730"(nucleolus)|go:"GO:0033551"(monopolin complex)|go:"GO:0034503"(protein localization to nucleolar rDNA repeats)|go:"GO:0034506"(chromosome, centromeric core domain)|go:"GO:0042802"(identical protein binding)|go:"GO:0045132"(meiotic chromosome segregation)|go:"GO:0045143"(homologous chromosome segregation)|go:"GO:0045144"(meiotic sister chromatid segregation)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051455"(monopolar spindle attachment to meiosis I kinetochore)|go:"GO:0070550"(rDNA condensation)|go:"GO:0072686"(mitotic spindle)|go:"GO:1990644"(microtubule site clamp)|interpro:IPR020981|interpro:IPR038608|interpro:IPR040349|interpro:IPR041671|rcsb pdb:3N4R|rcsb pdb:3N4S|rcsb pdb:3N4X|rcsb pdb:3N7N|rcsb pdb:5KTB|rcsb pdb:5V1A|rcsb pdb:5V3N|rcsb pdb:6DEI|mint:P25651	-	-	crc64:9650E0DA89B31CC5	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:AfeXaSlYyOOp2QaUjv0FRzdfTNY9606	rogid:rN1hGW+i7AN2+SmrIrwqz4ZSbQk559292	intact-crc:726C6E8D12DE390F|rigid:21rU79/LxmF6xVE+3TJFcYKgeYU	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q12476	uniprotkb:Q9BRK4	intact:EBI-31475|uniprotkb:D6VRH7|ensemblfungi:YDL175C	intact:EBI-741037|ensembl:ENSP00000359240|ensembl:ENSP00000359243|uniprotkb:Q8N3I0|uniprotkb:Q96J79|uniprotkb:Q96JL2|uniprotkb:B1AL14|uniprotkb:D3DR72	psi-mi:air2_yeast(display_long)|uniprotkb:Arginine methyltransferase-interacting RING finger protein 2(gene name synonym)|uniprotkb:AIR2(gene name)|psi-mi:AIR2(display_short)|uniprotkb:YDL175C(locus name)	psi-mi:lzts2_human(display_long)|uniprotkb:Protein LAPSER1(gene name synonym)|uniprotkb:LZTS2(gene name)|psi-mi:LZTS2(display_short)|uniprotkb:KIAA1813(gene name synonym)|uniprotkb:LAPSER1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554024|imex:IM-24995-4077	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010106.1|sgd:S000002334|dip:DIP-2543N|mint:Q12476|ensemblfungi:YDL175C(gene)|ensemblfungi:YDL175C_mRNA(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0006400"(tRNA modification)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031499"(TRAMP complex)|go:"GO:0043629"(ncRNA polyadenylation)|go:"GO:0071031"(nuclear mRNA surveillance of mRNA 3'-end processing)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071036"(nuclear polyadenylation-dependent snoRNA catabolic process)|go:"GO:0071037"(nuclear polyadenylation-dependent snRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071039"(nuclear polyadenylation-dependent CUT catabolic process)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR016713("Poly(A) polymerase complex, Air1/2")|interpro:IPR036875|rcsb pdb:2LLI|rcsb pdb:3NYB|rcsb pdb:4U4C	refseq:NP_115805.1|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030496"(midbody)|go:"GO:0031982"(vesicle)|go:"GO:0051013"(microtubule severing)|go:"GO:0051168"(nuclear export)|go:"GO:0051255"(spindle midzone assembly)|go:"GO:0060682"(primary ureteric bud growth)|go:"GO:0072197"(ureter morphogenesis)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|interpro:IPR028597|mint:Q9BRK4|ensembl:ENSG00000107816(gene)|ensembl:ENST00000370220(transcript)|ensembl:ENST00000370223(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0008285"(negative regulation of cell population proliferation)|refseq:XP_016872269.1|refseq:NP_001305028.1|refseq:NP_001305029.1|refseq:NP_001305030.1|refseq:XP_005270279.1	-	crc64:5915C97FA39D6AFC	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:bgMS2UPxQlkuE3+ip5+hgnIdNrE559292	rogid:OaMJmnmfm6JniKUJeyg7fS6zRcw9606	intact-crc:137872AA7B811A04|rigid:csCOY3mXj3Y8GtsSvIi66tvohpw	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P40455	uniprotkb:Q9BRK4	intact:EBI-25274|uniprotkb:D6VVD5|ensemblfungi:YIL152W	intact:EBI-741037|ensembl:ENSP00000359240|ensembl:ENSP00000359243|uniprotkb:Q8N3I0|uniprotkb:Q96J79|uniprotkb:Q96JL2|uniprotkb:B1AL14|uniprotkb:D3DR72	psi-mi:yip2_yeast(display_long)|uniprotkb:YIL152W(locus name)	psi-mi:lzts2_human(display_long)|uniprotkb:Protein LAPSER1(gene name synonym)|uniprotkb:LZTS2(gene name)|psi-mi:LZTS2(display_short)|uniprotkb:KIAA1813(gene name synonym)|uniprotkb:LAPSER1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554020|imex:IM-24995-4076	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000001414|refseq:NP_012114.1|mint:P40455|dip:DIP-2047N|ensemblfungi:YIL152W(gene)|ensemblfungi:YIL152W_mRNA(transcript)	refseq:NP_115805.1|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030496"(midbody)|go:"GO:0031982"(vesicle)|go:"GO:0051013"(microtubule severing)|go:"GO:0051168"(nuclear export)|go:"GO:0051255"(spindle midzone assembly)|go:"GO:0060682"(primary ureteric bud growth)|go:"GO:0072197"(ureter morphogenesis)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|interpro:IPR028597|mint:Q9BRK4|ensembl:ENSG00000107816(gene)|ensembl:ENST00000370220(transcript)|ensembl:ENST00000370223(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0008285"(negative regulation of cell population proliferation)|refseq:XP_016872269.1|refseq:NP_001305028.1|refseq:NP_001305029.1|refseq:NP_001305030.1|refseq:XP_005270279.1	-	crc64:07550E3F491F53A8	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:t5hCm1ck6kpFUxpEd8CsyLrHbEw559292	rogid:OaMJmnmfm6JniKUJeyg7fS6zRcw9606	intact-crc:AD7CC42A6A6F59C8|rigid:GoCOO6g/qfkgYjYzvQ4SGVZo+/Y	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P25372	uniprotkb:Q9BRK4	intact:EBI-19616|uniprotkb:D6VR84|ensemblfungi:YCR083W	intact:EBI-741037|ensembl:ENSP00000359240|ensembl:ENSP00000359243|uniprotkb:Q8N3I0|uniprotkb:Q96J79|uniprotkb:Q96JL2|uniprotkb:B1AL14|uniprotkb:D3DR72	psi-mi:trx3_yeast(display_long)|uniprotkb:TRX3(gene name)|psi-mi:TRX3(display_short)|uniprotkb:YCR83W(orf name)|uniprotkb:YCR083W(locus name)	psi-mi:lzts2_human(display_long)|uniprotkb:Protein LAPSER1(gene name synonym)|uniprotkb:LZTS2(gene name)|psi-mi:LZTS2(display_short)|uniprotkb:KIAA1813(gene name synonym)|uniprotkb:LAPSER1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554016|imex:IM-24995-4075	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR036249|refseq:NP_010006.1|sgd:S000000679|interpro:IPR017937|interpro:IPR013766(Thioredoxin domain)|rcsb pdb:2OE0|rcsb pdb:2OE1|rcsb pdb:2OE3|ensemblfungi:YCR083W(gene)|ensemblfungi:YCR083W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0015036"(disulfide oxidoreductase activity)|go:"GO:0034599"(cellular response to oxidative stress)|rcsb pdb:5YKW	refseq:NP_115805.1|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030496"(midbody)|go:"GO:0031982"(vesicle)|go:"GO:0051013"(microtubule severing)|go:"GO:0051168"(nuclear export)|go:"GO:0051255"(spindle midzone assembly)|go:"GO:0060682"(primary ureteric bud growth)|go:"GO:0072197"(ureter morphogenesis)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|interpro:IPR028597|mint:Q9BRK4|ensembl:ENSG00000107816(gene)|ensembl:ENST00000370220(transcript)|ensembl:ENST00000370223(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0008285"(negative regulation of cell population proliferation)|refseq:XP_016872269.1|refseq:NP_001305028.1|refseq:NP_001305029.1|refseq:NP_001305030.1|refseq:XP_005270279.1	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:g0xjGf9GvJRl8iv2qoT5tOs7jXI559292	rogid:OaMJmnmfm6JniKUJeyg7fS6zRcw9606	intact-crc:BF805D80834AE371|rigid:v5gLRQMqyctMImI8qbPOhcFVTqE	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P32464	uniprotkb:Q9BRK4	intact:EBI-8859|ensemblfungi:YKL189W|uniprotkb:D6VX11	intact:EBI-741037|ensembl:ENSP00000359240|ensembl:ENSP00000359243|uniprotkb:Q8N3I0|uniprotkb:Q96J79|uniprotkb:Q96JL2|uniprotkb:B1AL14|uniprotkb:D3DR72	psi-mi:hym1_yeast(display_long)|uniprotkb:YKL189W(locus name)|uniprotkb:HYM1(gene name)|psi-mi:HYM1(display_short)	psi-mi:lzts2_human(display_long)|uniprotkb:Protein LAPSER1(gene name synonym)|uniprotkb:LZTS2(gene name)|psi-mi:LZTS2(display_short)|uniprotkb:KIAA1813(gene name synonym)|uniprotkb:LAPSER1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554012|imex:IM-24995-4074	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YKL189W(gene)|ensemblfungi:YKL189W_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0000920"(septum digestion after cytokinesis)|go:"GO:0005933"(cellular bud)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007118"(budding cell apical bud growth)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043332"(mating projection tip)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0044732"(mitotic spindle pole body)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013878(Mo25-like)|interpro:IPR016024(Armadillo-type fold)|reactome:R-SCE-6798695|refseq:NP_012732.1|sgd:S000001672|mint:P32464|dip:DIP-5425N	refseq:NP_115805.1|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030496"(midbody)|go:"GO:0031982"(vesicle)|go:"GO:0051013"(microtubule severing)|go:"GO:0051168"(nuclear export)|go:"GO:0051255"(spindle midzone assembly)|go:"GO:0060682"(primary ureteric bud growth)|go:"GO:0072197"(ureter morphogenesis)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|interpro:IPR028597|mint:Q9BRK4|ensembl:ENSG00000107816(gene)|ensembl:ENST00000370220(transcript)|ensembl:ENST00000370223(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0008285"(negative regulation of cell population proliferation)|refseq:XP_016872269.1|refseq:NP_001305028.1|refseq:NP_001305029.1|refseq:NP_001305030.1|refseq:XP_005270279.1	-	crc64:F48860754C892BA9	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:pOlQFFuYgFzmqf3ZGUVkBj9h7Uc559292	rogid:OaMJmnmfm6JniKUJeyg7fS6zRcw9606	intact-crc:AB538527FBC167FC|rigid:mGzOaKzCbGqGbkKZDZDgf+WUa10	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9BRK4	uniprotkb:P18961	intact:EBI-741037|ensembl:ENSP00000359240|ensembl:ENSP00000359243|uniprotkb:Q8N3I0|uniprotkb:Q96J79|uniprotkb:Q96JL2|uniprotkb:B1AL14|uniprotkb:D3DR72	intact:EBI-29484|uniprotkb:D6VZS6|ensemblfungi:YMR104C	psi-mi:lzts2_human(display_long)|uniprotkb:Protein LAPSER1(gene name synonym)|uniprotkb:LZTS2(gene name)|psi-mi:LZTS2(display_short)|uniprotkb:KIAA1813(gene name synonym)|uniprotkb:LAPSER1(gene name synonym)	psi-mi:ypk2_yeast(display_long)|uniprotkb:YPK2(gene name)|psi-mi:YPK2(display_short)|uniprotkb:YKR2(gene name synonym)|uniprotkb:YMR104C(locus name)|uniprotkb:YM9718.03C(orf name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554028|imex:IM-24995-4078	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_115805.1|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030496"(midbody)|go:"GO:0031982"(vesicle)|go:"GO:0051013"(microtubule severing)|go:"GO:0051168"(nuclear export)|go:"GO:0051255"(spindle midzone assembly)|go:"GO:0060682"(primary ureteric bud growth)|go:"GO:0072197"(ureter morphogenesis)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|interpro:IPR028597|mint:Q9BRK4|ensembl:ENSG00000107816(gene)|ensembl:ENST00000370220(transcript)|ensembl:ENST00000370223(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0008285"(negative regulation of cell population proliferation)|refseq:XP_016872269.1|refseq:NP_001305028.1|refseq:NP_001305029.1|refseq:NP_001305030.1|refseq:XP_005270279.1	refseq:NP_013822.1|sgd:S000004710|dip:DIP-4438N|mint:P18961|ensemblfungi:YMR104C(gene)|ensemblfungi:YMR104C_mRNA(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0060237"(regulation of fungal-type cell wall organization)|go:"GO:0070941"(eisosome assembly)|go:"GO:0071555"(cell wall organization)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892	-	-	crc64:E1FAB0295386A113	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:OaMJmnmfm6JniKUJeyg7fS6zRcw9606	rogid:wDHCJlSmOMy9MWExwxHzLA4+dO0559292	intact-crc:2B9CDEF7CBF90059|rigid:jd2ap/wQphjhYJ/mLe0t8IsF0HU	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q03920	uniprotkb:Q9BUY5	intact:EBI-31378|uniprotkb:D6VSC3|ensemblfungi:YDR140W	intact:EBI-743265|ensembl:ENSP00000253115|ensembl:ENSP00000439017|uniprotkb:B3KTL2	psi-mi:mtq2_yeast(display_long)|uniprotkb:MTQ2(gene name)|psi-mi:MTQ2(display_short)|uniprotkb:MTC6(gene name synonym)|uniprotkb:"N(5)-glutamine methyltransferase MTQ2"(gene name synonym)|uniprotkb:YDR140W(locus name)	psi-mi:zn426_human(display_long)|uniprotkb:ZNF426(gene name)|psi-mi:ZNF426(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554076|imex:IM-24995-4090	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010424.3|sgd:S000002547|dip:DIP-1755N|mint:Q03920|ensemblfungi:YDR140W(gene)|ensemblfungi:YDR140W_mRNA(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006417"(regulation of translation)|go:"GO:0008276"(protein methyltransferase activity)|go:"GO:0008757"(S-adenosylmethionine-dependent methyltransferase activity)|go:"GO:0018364"(peptidyl-glutamine methylation)|go:"GO:0035657"(eRF1 methyltransferase complex)|go:"GO:0102559"("protein-(glutamine-N5) methyltransferase activity")|interpro:IPR002052(N-6 adenine-specific DNA methylase, conserved site)|interpro:IPR004557(Putative methylase)|interpro:IPR007848(Methyltransferase small)|interpro:IPR029063|reactome:R-SCE-156581|reactome:R-SCE-72764	refseq:NP_077011.1|ensembl:ENSG00000130818(gene)|ensembl:ENST00000253115(transcript)|ensembl:ENST00000535489(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|refseq:NP_001304984.1|refseq:NP_001304985.1	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:pu/ERTe9ojnsy8nxRKkRA+sHq80559292	rogid:QPI15/Fod+FtlArvKKNMPGSu3zQ9606	intact-crc:D818F8BC0B8211D6|rigid:XdZxrTaU/RWJjyUcL48LBOGZOr8	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P48232	uniprotkb:Q9BUW7	intact:EBI-28775|uniprotkb:D6W193|ensemblfungi:YNL086W	intact:EBI-752084|uniprotkb:Q9Y3F7|uniprotkb:Q5SYV8|ensembl:ENSP00000362085	psi-mi:snapn_yeast(display_long)|uniprotkb:YNL086W(locus name)|uniprotkb:N2254(orf name)|uniprotkb:SNN1(gene name)|psi-mi:SNN1(display_short)|uniprotkb:SNAPIN-like protein 1(gene name synonym)	psi-mi:bbln_human(display_long)|uniprotkb:BBLN(gene name)|psi-mi:BBLN(display_short)|uniprotkb:C9orf16(gene name synonym)|uniprotkb:UPF0184 protein C9orf16(gene name synonym)|uniprotkb:EST00098(orf name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554072|imex:IM-24995-4089	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014313.1|sgd:S000005030|dip:DIP-1188N|mint:P48232|ensemblfungi:YNL086W(gene)|ensemblfungi:YNL086W_mRNA(transcript)|go:"GO:0005768"(endosome)|go:"GO:0007032"(endosome organization)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0032880"(regulation of protein localization)	refseq:NP_077017.1|dip:DIP-29481N|ensembl:ENSG00000171159(gene)|ensembl:ENST00000372994(transcript)|interpro:IPR005374(Protein of unknown function UPF0184)	-	crc64:33200D2F0F729DA1	crc64:EBE1D0AFAAD6DABB	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:XCPaHuGC9oKD/3W0gY5ZY8jKtFs559292	rogid:O4VcHghk63gMrjyh5XKmkZovFZ49606	intact-crc:36986DE73D2600EC|rigid:iljLLz95tUWEiho68kbnmxPDoTE	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9BUW7	uniprotkb:P32610	intact:EBI-752084|uniprotkb:Q9Y3F7|uniprotkb:Q5SYV8|ensembl:ENSP00000362085	intact:EBI-20264|uniprotkb:D3DLJ9|ensemblfungi:YEL051W	psi-mi:bbln_human(display_long)|uniprotkb:BBLN(gene name)|psi-mi:BBLN(display_short)|uniprotkb:C9orf16(gene name synonym)|uniprotkb:UPF0184 protein C9orf16(gene name synonym)|uniprotkb:EST00098(orf name)	psi-mi:vatd_yeast(display_long)|uniprotkb:VMA8(gene name)|psi-mi:VMA8(display_short)|uniprotkb:YEL051W(locus name)|uniprotkb:SYGP-ORF11(orf name)|uniprotkb:Vacuolar proton pump subunit D(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554068|imex:IM-24995-4088	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_077017.1|dip:DIP-29481N|ensembl:ENSG00000171159(gene)|ensembl:ENST00000372994(transcript)|interpro:IPR005374(Protein of unknown function UPF0184)	refseq:NP_010863.1|sgd:S000000777|ensemblfungi:YEL051W(gene)|ensemblfungi:YEL051W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0016471"(vacuolar proton-transporting V-type ATPase complex)|go:"GO:0033176"(proton-transporting V-type ATPase complex)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR002699(ATPase, V1/A1 complex, subunit D)|rcsb pdb:3J9T|rcsb pdb:3J9U|rcsb pdb:3J9V|rcsb pdb:4RND|rcsb pdb:5BW9|rcsb pdb:5D80|rcsb pdb:5VOX|rcsb pdb:5VOY|rcsb pdb:5VOZ|rcsb pdb:6O7V|rcsb pdb:6O7W|rcsb pdb:6O7X|reactome:R-SCE-1222556|reactome:R-SCE-6798695|reactome:R-SCE-77387|reactome:R-SCE-917977|reactome:R-SCE-9639288|dip:DIP-2959N|mint:P32610	-	crc64:EBE1D0AFAAD6DABB	crc64:FDE93E1FAF0AEC5B	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:O4VcHghk63gMrjyh5XKmkZovFZ49606	rogid:rrwRno7lCnDeTNwawONkGwV8Hkg559292	intact-crc:6E143796E9192490|rigid:HBf3s4T1v7ErHlrRAY5ESbOe+30	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q06819	uniprotkb:Q9BUT1	intact:EBI-166|ensemblfungi:YPR082C|uniprotkb:D6W484	intact:EBI-6137689|uniprotkb:A8K295|uniprotkb:B4DUF6|uniprotkb:Q503A0|uniprotkb:Q6IA46|uniprotkb:Q6UWD3|uniprotkb:Q9H8S8|uniprotkb:Q9NRX8|ensembl:ENSP00000296424	psi-mi:dib1_yeast(display_long)|uniprotkb:DIB1(gene name)|psi-mi:DIB1(display_short)|uniprotkb:CDH1(gene name synonym)|uniprotkb:SNU16(gene name synonym)|uniprotkb:YPR082C(locus name)|uniprotkb:P9513.12(orf name)	psi-mi:bdh2_human(display_long)|uniprotkb:SDR15C1(gene name synonym)|uniprotkb:Short chain dehydrogenase/reductase family 15C member 1(gene name synonym)|uniprotkb:UNQ6308/PRO20933(orf name)|uniprotkb:BDH2(gene name)|psi-mi:BDH2(display_short)|uniprotkb:DHRS6(gene name synonym)|uniprotkb:Dehydrogenase/reductase SDR family member 6(gene name synonym)|uniprotkb:Oxidoreductase UCPA(gene name synonym)|uniprotkb:R-beta-hydroxybutyrate dehydrogenase(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554064|imex:IM-24995-4087	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015407.1|sgd:S000006286|ensemblfungi:YPR082C(gene)|ensemblfungi:YPR082C_mRNA(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005682"(U5 snRNP)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|interpro:IPR004123(mRNA splicing factor, thioredoxin-like U5 snRNP)|interpro:IPR036249|rcsb pdb:3JCM|rcsb pdb:5GAN|rcsb pdb:5GAP|rcsb pdb:5NRL|rcsb pdb:5ZWM|rcsb pdb:5ZWO|dip:DIP-1289N	refseq:XP_011530430.1|refseq:NP_064524.3|refseq:XP_016863951.1|ensembl:ENSG00000164039(gene)|ensembl:ENST00000296424(transcript)|go:"GO:0003858"(3-hydroxybutyrate dehydrogenase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0016616"(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|go:"GO:0016628"(oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor)|go:"GO:0019290"(siderophore biosynthetic process)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0042168"(heme metabolic process)|go:"GO:0051287"(NAD binding)|go:"GO:0055072"(iron ion homeostasis)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR020904|interpro:IPR036291|rcsb pdb:2AG5|reactome:R-HSA-77111	-	crc64:B8C11278571C57E5	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:mRibIpinKPlRNdh60VJj/Z0tjUc559292	rogid:jo1enuFW27NpCn5SWMEBipbUKXA9606	intact-crc:5403DC672C6B3142|rigid:PXBSTSrHAtEBVhKdNzJ15cl3Y9w	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P30665	uniprotkb:Q9BTE3-2	intact:EBI-4326|uniprotkb:D6W429|ensemblfungi:YPR019W	intact:EBI-9384556|ensembl:ENSP00000358073	psi-mi:mcm4_yeast(display_long)|uniprotkb:MCM4(gene name)|psi-mi:MCM4(display_short)|uniprotkb:HCD21(gene name synonym)|uniprotkb:YPR019W(locus name)|uniprotkb:YP9531.13(orf name)|uniprotkb:CDC54(gene name synonym)|uniprotkb:Cell division control protein 54(gene name synonym)	psi-mi:q9bte3-2(display_long)|uniprotkb:MCMBP(gene name)|psi-mi:MCMBP(display_short)|uniprotkb:C10orf119(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554060|imex:IM-24995-4086	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-2409N|refseq:NP_015344.1|sgd:S000006223|mint:P30665|ensemblfungi:YPR019W(gene)|ensemblfungi:YPR019W_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0033260"(nuclear DNA replication)|go:"GO:0034214"(protein hexamerization)|go:"GO:0042555"(MCM complex)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0071162"(CMG complex)|go:"GO:0097373"(MCM core complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902975"(mitotic DNA replication initiation)|interpro:IPR001208(MCM)|interpro:IPR008047(MCM protein 4)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR036388|interpro:IPR041562|rcsb pdb:3JA8|rcsb pdb:3JC5|rcsb pdb:3JC6|rcsb pdb:3JC7|rcsb pdb:5BK4|rcsb pdb:5U8S|rcsb pdb:5U8T|rcsb pdb:5V8F|rcsb pdb:5XF8|rcsb pdb:6EYC|rcsb pdb:6F0L|rcsb pdb:6HV9|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6RQC|rcsb pdb:6SKL|rcsb pdb:6SKO|rcsb pdb:6U0M|rcsb pdb:6WGF|rcsb pdb:6WGG|rcsb pdb:6WGI|reactome:R-SCE-68949|reactome:R-SCE-68962|reactome:R-SCE-69052	intact:EBI-749378(isoform-parent)|uniprotkb:Q9BTE3-2(isoform-parent)|ensembl:ENSG00000197771(gene)|ensembl:ENST00000369077(transcript)	-	crc64:382D542AE38975E3	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:KpsdSZBisjpmXnNAJTZncPINxYI559292	rogid:nJOq6jis1maK+M/X0TcR44HlxRw9606	intact-crc:88095AA3D0511523|rigid:YECPGzZy7IokEtBFfv3t22SmfDw	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q12083	uniprotkb:Q9BRK4	intact:EBI-31634|uniprotkb:D6W3K4|ensemblfungi:YPL164C	intact:EBI-741037|ensembl:ENSP00000359240|ensembl:ENSP00000359243|uniprotkb:Q8N3I0|uniprotkb:Q96J79|uniprotkb:Q96JL2|uniprotkb:B1AL14|uniprotkb:D3DR72	psi-mi:mlh3_yeast(display_long)|uniprotkb:MLH3(gene name)|psi-mi:MLH3(display_short)|uniprotkb:MutL protein homolog 3(gene name synonym)|uniprotkb:P2550(orf name)|uniprotkb:YPL164C(locus name)	psi-mi:lzts2_human(display_long)|uniprotkb:Protein LAPSER1(gene name synonym)|uniprotkb:LZTS2(gene name)|psi-mi:LZTS2(display_short)|uniprotkb:KIAA1813(gene name synonym)|uniprotkb:LAPSER1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554032|imex:IM-24995-4079	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015161.1|sgd:S000006085|dip:DIP-2414N|ensemblfungi:YPL164C(gene)|ensemblfungi:YPL164C_mRNA(transcript)|go:"GO:0000710"(meiotic mismatch repair)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006298"(mismatch repair)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0030983"(mismatched DNA binding)|go:"GO:0032300"(mismatch repair complex)|go:"GO:0097587"(MutLgamma complex)|interpro:IPR013507(DNA mismatch repair protein, C-terminal)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR014790(MutL, C-terminal, dimerisation)|interpro:IPR020568|interpro:IPR028830|interpro:IPR036890|interpro:IPR037198|interpro:IPR038973|interpro:IPR042120|rcsb pdb:6RMN|rcsb pdb:6SHX|rcsb pdb:6SNS|rcsb pdb:6SNV	refseq:NP_115805.1|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030496"(midbody)|go:"GO:0031982"(vesicle)|go:"GO:0051013"(microtubule severing)|go:"GO:0051168"(nuclear export)|go:"GO:0051255"(spindle midzone assembly)|go:"GO:0060682"(primary ureteric bud growth)|go:"GO:0072197"(ureter morphogenesis)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|interpro:IPR028597|mint:Q9BRK4|ensembl:ENSG00000107816(gene)|ensembl:ENST00000370220(transcript)|ensembl:ENST00000370223(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0008285"(negative regulation of cell population proliferation)|refseq:XP_016872269.1|refseq:NP_001305028.1|refseq:NP_001305029.1|refseq:NP_001305030.1|refseq:XP_005270279.1	-	crc64:970FD7F57EB6E3B1	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:g47/5yM9oWZ13CIZOZ7QT6A+LW0559292	rogid:OaMJmnmfm6JniKUJeyg7fS6zRcw9606	intact-crc:42F223CA607619EC|rigid:tr5QsIWPV4A3k7Sonu0je+Nrc7w	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P24279	uniprotkb:Q9BTE3-2	intact:EBI-10541|ensemblfungi:YEL032W|uniprotkb:D3DLL7	intact:EBI-9384556|ensembl:ENSP00000358073	psi-mi:mcm3_yeast(display_long)|uniprotkb:MCM3(gene name)|psi-mi:MCM3(display_short)|uniprotkb:YEL032W(locus name)|uniprotkb:SYGP-ORF23(orf name)|uniprotkb:Minichromosome maintenance protein 3(gene name synonym)	psi-mi:q9bte3-2(display_long)|uniprotkb:MCMBP(gene name)|psi-mi:MCMBP(display_short)|uniprotkb:C10orf119(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554056|imex:IM-24995-4085	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010882.1|sgd:S000000758|go:"GO:0005524"(ATP binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006348"|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0042555"(MCM complex)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902975"(mitotic DNA replication initiation)|go:"GO:1904931"(MCM complex binding)|interpro:IPR001208(MCM)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR008046(MCM protein 3)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|rcsb pdb:3JA8|rcsb pdb:3JC5|rcsb pdb:3JC6|rcsb pdb:3JC7|rcsb pdb:5BK4|rcsb pdb:5U8S|rcsb pdb:5U8T|rcsb pdb:5V8F|rcsb pdb:6EYC|rcsb pdb:6F0L|rcsb pdb:6HV9|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6RQC|rcsb pdb:6SKL|rcsb pdb:6SKO|rcsb pdb:6U0M|rcsb pdb:6WGC|rcsb pdb:6WGF|rcsb pdb:6WGG|rcsb pdb:6WGI|reactome:R-SCE-68949|reactome:R-SCE-68962|reactome:R-SCE-69052|rcsb pdb:5XF8|ensemblfungi:YEL032W(gene)|ensemblfungi:YEL032W_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|mint:P24279|dip:DIP-2407N	intact:EBI-749378(isoform-parent)|uniprotkb:Q9BTE3-2(isoform-parent)|ensembl:ENSG00000197771(gene)|ensembl:ENST00000369077(transcript)	-	crc64:43DD4DACAF4456DC	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:OsFbdaTeE1vPQObriGt5M6mTPzk559292	rogid:nJOq6jis1maK+M/X0TcR44HlxRw9606	intact-crc:DF0D6B6F8650FA90|rigid:vu2Hl8RYLaSrtUaj8zIr7gqfUhw	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q03362	uniprotkb:Q9BSE4	intact:EBI-2057915|uniprotkb:D6VT99|ensemblfungi:YDR476C	intact:EBI-2868124|uniprotkb:A4D1Y8|uniprotkb:Q9H6F9|ensembl:ENSP00000310729|ensembl:ENSP00000379390	psi-mi:yd476_yeast(display_long)|uniprotkb:YDR476C(locus name)	psi-mi:herp2_human(display_long)|uniprotkb:HERPUD2(gene name)|psi-mi:HERPUD2(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554052|imex:IM-24995-4084	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002884|refseq:NP_010764.1|mint:Q03362|ensemblfungi:YDR476C(gene)|ensemblfungi:YDR476C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)	refseq:NP_071768.3|refseq:XP_016867995.1|ensembl:ENSG00000122557(gene)|ensembl:ENST00000311350(transcript)|ensembl:ENST00000396081(transcript)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|interpro:IPR000626(Ubiquitin)|interpro:IPR029071|interpro:IPR039751|rcsb pdb:2KDB	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:YEqaI+xtDR2srSbbY5vQtWY+h6s559292	rogid:h4jBbYdKwKQBN6Jd3/QQA0hNOQw9606	intact-crc:20E47D8B4E8DC3BC|rigid:OJa1EzKTf96bXA5efxhhBZ6EO/s	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9BSE2	uniprotkb:P52870	intact:EBI-8649725|ensembl:ENSP00000295694|ensembl:ENSP00000384748|intact:MINT-8163648|uniprotkb:D3DVB8|uniprotkb:B2RE22	intact:EBI-16410|ensemblfungi:YER087C-B|uniprotkb:D3DLZ4	psi-mi:tmm79_human(display_long)|uniprotkb:MATT(gene name synonym)|uniprotkb:TMEM79(gene name)|psi-mi:TMEM79(display_short)|uniprotkb:Mattrin(gene name synonym)	psi-mi:sc6b1_yeast(display_long)|uniprotkb:Sec61 complex subunit SBH1(gene name synonym)|uniprotkb:YER087BC(orf name)|uniprotkb:YER087C-B(locus name)|uniprotkb:SBH1(gene name)|psi-mi:SBH1(display_short)|uniprotkb:SEB1(gene name synonym)|uniprotkb:Sec61 complex subunit beta(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554044|imex:IM-24995-4082	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000163472(gene)|ensembl:ENST00000295694(transcript)|ensembl:ENST00000405535(transcript)|go:"GO:0002070"(epithelial cell maturation)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031069"(hair follicle morphogenesis)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0042335"(cuticle development)|go:"GO:0042802"(identical protein binding)|go:"GO:0045055"(regulated exocytosis)|go:"GO:0045684"(positive regulation of epidermis development)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070268"(cornification)|mint:Q9BSE2|refseq:NP_115699.1	ensemblfungi:YER087C-B(gene)|ensemblfungi:YER087C-B_mRNA(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|interpro:IPR016482(Preprotein translocase Sec, Sec61-beta subunit, eukarya)|interpro:IPR030671|rcsb pdb:6N3Q|rcsb pdb:6ND1|rcsb pdb:7AFT|rcsb pdb:7KAH|rcsb pdb:7KAI|sgd:S000002128|rcsb pdb:7KAJ|rcsb pdb:7KAO|rcsb pdb:7KAP|rcsb pdb:7KAQ|rcsb pdb:7KAR|rcsb pdb:7KAS|rcsb pdb:7KAT|rcsb pdb:7KAU|rcsb pdb:7KB5|refseq:NP_011011.3|dip:DIP-5681N|mint:P52870	-	comment:mint	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:QdmILKEdTJzJUhBdigw/4vC4R3o9606	rogid:9cYnDPhmMpAOdB2GV5TxikzpjI0559292	intact-crc:1E32873D4465089B|rigid:cSjcXahvE4kqU+2ue6xd72Sc1Rg	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9BSE2	uniprotkb:P39547	intact:EBI-8649725|ensembl:ENSP00000295694|ensembl:ENSP00000384748|intact:MINT-8163648|uniprotkb:D3DVB8|uniprotkb:B2RE22	intact:EBI-20760|uniprotkb:D6VPM9|ensemblfungi:YAR027W	psi-mi:tmm79_human(display_long)|uniprotkb:MATT(gene name synonym)|uniprotkb:TMEM79(gene name)|psi-mi:TMEM79(display_short)|uniprotkb:Mattrin(gene name synonym)	psi-mi:uip3_yeast(display_long)|uniprotkb:UIP3(gene name)|psi-mi:UIP3(display_short)|uniprotkb:YAR027W(locus name)|uniprotkb:FUN55(orf name)|uniprotkb:DUP240 protein UIP3(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554040|imex:IM-24995-4081	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000163472(gene)|ensembl:ENST00000295694(transcript)|ensembl:ENST00000405535(transcript)|go:"GO:0002070"(epithelial cell maturation)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031069"(hair follicle morphogenesis)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0042335"(cuticle development)|go:"GO:0042802"(identical protein binding)|go:"GO:0045055"(regulated exocytosis)|go:"GO:0045684"(positive regulation of epidermis development)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070268"(cornification)|mint:Q9BSE2|refseq:NP_115699.1	sgd:S000000075|refseq:NP_009414.1|ensemblfungi:YAR027W(gene)|ensemblfungi:YAR027W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031965"(nuclear membrane)|interpro:IPR001142(Yeast membrane protein DUP)|dip:DIP-2031N	-	comment:mint	crc64:9DBF29F9C2395AB2	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:QdmILKEdTJzJUhBdigw/4vC4R3o9606	rogid:2Eb82iBxbdvlroWw/nM4BQeiVIc559292	intact-crc:DA8BA8356C9F91C8|rigid:9DZxVoVQDjwUMiByyxSNbVWEbJ0	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9BRK4	uniprotkb:P40454	intact:EBI-741037|ensembl:ENSP00000359240|ensembl:ENSP00000359243|uniprotkb:Q8N3I0|uniprotkb:Q96J79|uniprotkb:Q96JL2|uniprotkb:B1AL14|uniprotkb:D3DR72	intact:EBI-25278|uniprotkb:D6VVD4|ensemblfungi:YIL153W	psi-mi:lzts2_human(display_long)|uniprotkb:Protein LAPSER1(gene name synonym)|uniprotkb:LZTS2(gene name)|psi-mi:LZTS2(display_short)|uniprotkb:KIAA1813(gene name synonym)|uniprotkb:LAPSER1(gene name synonym)	psi-mi:ptpa1_yeast(display_long)|uniprotkb:YIL153W(locus name)|uniprotkb:RRD1(gene name)|psi-mi:RRD1(display_short)|uniprotkb:NCS1(gene name synonym)|uniprotkb:YPA1(gene name synonym)|uniprotkb:Peptidyl-prolyl cis-trans isomerase PTPA-1(gene name synonym)|uniprotkb:Phosphotyrosyl phosphatase activator 1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554036|imex:IM-24995-4080	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_115805.1|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030496"(midbody)|go:"GO:0031982"(vesicle)|go:"GO:0051013"(microtubule severing)|go:"GO:0051168"(nuclear export)|go:"GO:0051255"(spindle midzone assembly)|go:"GO:0060682"(primary ureteric bud growth)|go:"GO:0072197"(ureter morphogenesis)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|interpro:IPR028597|mint:Q9BRK4|ensembl:ENSG00000107816(gene)|ensembl:ENST00000370220(transcript)|ensembl:ENST00000370223(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0008285"(negative regulation of cell population proliferation)|refseq:XP_016872269.1|refseq:NP_001305028.1|refseq:NP_001305029.1|refseq:NP_001305030.1|refseq:XP_005270279.1	refseq:NP_012113.1|sgd:S000001415|mint:P40454|dip:DIP-5663N|ensemblfungi:YIL153W(gene)|ensemblfungi:YIL153W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006914"(autophagy)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008160"(protein tyrosine phosphatase activator activity)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0043618"(regulation of transcription from RNA polymerase II promoter in response to stress)|interpro:IPR004327(Phosphotyrosyl phosphatase activator, PTPA)|interpro:IPR037218|interpro:IPR043170|rcsb pdb:2IXO|rcsb pdb:2IXP	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:OaMJmnmfm6JniKUJeyg7fS6zRcw9606	rogid:It2q8WlpmvLEZ1fqpRF5Fypw9Q4559292	intact-crc:54CB0973BBE260C9|rigid:vNww3lkR6EPnywLIB41ksn2lzxs	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9BSE2	uniprotkb:P15303	intact:EBI-8649725|ensembl:ENSP00000295694|ensembl:ENSP00000384748|intact:MINT-8163648|uniprotkb:D3DVB8|uniprotkb:B2RE22	intact:EBI-16584|ensemblfungi:YPR181C|uniprotkb:D6W4I1	psi-mi:tmm79_human(display_long)|uniprotkb:MATT(gene name synonym)|uniprotkb:TMEM79(gene name)|psi-mi:TMEM79(display_short)|uniprotkb:Mattrin(gene name synonym)	psi-mi:sec23_yeast(display_long)|uniprotkb:SEC23(gene name)|psi-mi:SEC23(display_short)|uniprotkb:P9705.14(orf name)|uniprotkb:YPR181C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554048|imex:IM-24995-4083	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000163472(gene)|ensembl:ENST00000295694(transcript)|ensembl:ENST00000405535(transcript)|go:"GO:0002070"(epithelial cell maturation)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031069"(hair follicle morphogenesis)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0042335"(cuticle development)|go:"GO:0042802"(identical protein binding)|go:"GO:0045055"(regulated exocytosis)|go:"GO:0045684"(positive regulation of epidermis development)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070268"(cornification)|mint:Q9BSE2|refseq:NP_115699.1	refseq:NP_015507.1|sgd:S000006385|ensemblfungi:YPR181C(gene)|ensemblfungi:YPR181C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003400"(regulation of COPII vesicle coating)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016236"(macroautophagy)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0061709"(reticulophagy)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:0090110"(COPII-coated vesicle cargo loading)|interpro:IPR006895(Zinc finger, Sec23/Sec24-type)|interpro:IPR006896(Sec23/Sec24 trunk region)|interpro:IPR006900(Sec23/Sec24 helical region)|interpro:IPR007123(Gelsolin region)|interpro:IPR012990(Sec23/Sec24 beta-sandwich)|interpro:IPR029006|interpro:IPR036174|interpro:IPR036175|interpro:IPR036180|interpro:IPR036465|interpro:IPR037364|interpro:IPR037550|rcsb pdb:1M2O|rcsb pdb:2QTV|rcsb pdb:4BZI|rcsb pdb:6GNI|rcsb pdb:6ZGA|reactome:R-SCE-204005|reactome:R-SCE-5694530|reactome:R-SCE-983170|rcsb pdb:1M2V|dip:DIP-2232N|mint:P15303	-	comment:mint	crc64:69811913848265FB	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:QdmILKEdTJzJUhBdigw/4vC4R3o9606	rogid:IqC3qOrbef6aMHBztUW5+7DZ4IQ559292	intact-crc:F29DAE692C4F028E|rigid:24mlGqSFa+DOaxDKtlfF/GK7GEg	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9BYV6-2	uniprotkb:P23180	intact:EBI-11522718|ensembl:ENSP00000297348	intact:EBI-24332|uniprotkb:D3DKP4|ensemblfungi:YHL021C	psi-mi:q9byv6-2(display_long)|uniprotkb:TRIM55(gene name)|psi-mi:TRIM55(display_short)|uniprotkb:MURF2(gene name synonym)|uniprotkb:Muscle-specific RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 29(gene name synonym)|uniprotkb:RNF29(gene name synonym)|uniprotkb:p50(isoform synonym)	psi-mi:aim17_yeast(display_long)|uniprotkb:AIM17(gene name)|psi-mi:AIM17(display_short)|uniprotkb:FMP12(gene name synonym)|uniprotkb:Altered inheritance of mitochondria protein 17, mitochondrial(gene name synonym)|uniprotkb:Found in mitochondrial proteome protein 12(gene name synonym)|uniprotkb:YHL021C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554124|imex:IM-24995-4102	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-2341179(isoform-parent)|uniprotkb:Q9BYV6-2(isoform-parent)|ensembl:ENSG00000147573(gene)|ensembl:ENST00000353317(transcript)	refseq:NP_011842.1|sgd:S000001013|reactome:R-SCE-71262|dip:DIP-4919N|ensemblfungi:YHL021C(gene)|ensemblfungi:YHL021C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0045329"(carnitine biosynthetic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0051213"(dioxygenase activity)|interpro:IPR003819(Taurine catabolism dioxygenase TauD/TfdA)|interpro:IPR042098	-	-	crc64:568B17051DB60899	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:9t8UhK+Z1yBqjnQrOqPD76NuXGg9606	rogid:EckG7oFiGF7UJou9Cu2fZCGiUKE559292	intact-crc:1F2503A00F47F995|rigid:r5UIlR4ULSzRqRpAZyIMdIwM8e8	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9BXL8	uniprotkb:P38770	intact:EBI-1773949|uniprotkb:Q8TB18|uniprotkb:Q9NWK7|ensembl:ENSP00000337226|ensembl:ENSP00000376369	intact:EBI-24507|uniprotkb:D3DKY3|ensemblfungi:YHR036W	psi-mi:cdca4_human(display_long)|uniprotkb:CDCA4(gene name)|psi-mi:CDCA4(display_short)|uniprotkb:HEPP(gene name synonym)|uniprotkb:Hematopoietic progenitor protein(gene name synonym)	psi-mi:brl1_yeast(display_long)|uniprotkb:BRL1(gene name)|psi-mi:BRL1(display_short)|uniprotkb:BRR6-like protein 1(gene name synonym)|uniprotkb:YHR036W(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554120|imex:IM-24995-4101	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060425.2|refseq:NP_663747.1|ensembl:ENSG00000170779(gene)|ensembl:ENST00000336219(transcript)|ensembl:ENST00000392590(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0048096"|interpro:IPR009263(SERTA)|mint:Q9BXL8	refseq:NP_011901.1|sgd:S000001078|dip:DIP-5580N|mint:P38770|ensemblfungi:YHR036W(gene)|ensemblfungi:YHR036W_mRNA(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006998"(nuclear envelope organization)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0051028"(mRNA transport)|go:"GO:0055088"(lipid homeostasis)|interpro:IPR018767|interpro:IPR040202	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:sxwZ0Yw0uG+MjnhKtVv+8PHvPCo9606	rogid:gLJXF3VREvr8+oW8HZYTfHDho4A559292	intact-crc:4F898722859C8CB5|rigid:X/OgNRGYdVkcb3UluzUCgcjpNdI	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q12154	uniprotkb:Q9BXJ1-2	intact:EBI-2989|uniprotkb:Q6B1B6|uniprotkb:D6VRQ0|ensemblfungi:YDL100C	intact:EBI-11536642	psi-mi:get3_yeast(display_long)|uniprotkb:YDL100C(locus name)|uniprotkb:GET3(gene name)|psi-mi:GET3(display_short)|uniprotkb:ARR4(gene name synonym)|uniprotkb:D2371(orf name)|uniprotkb:Arsenical pump-driving ATPase(gene name synonym)|uniprotkb:Arsenite-stimulated ATPase(gene name synonym)|uniprotkb:Guided entry of tail-anchored proteins 3(gene name synonym)|uniprotkb:Golgi to ER traffic protein 3(gene name synonym)	psi-mi:q9bxj1-2(display_long)|uniprotkb:CTRP1(gene name synonym)|uniprotkb:G protein-coupled receptor-interacting protein(gene name synonym)|uniprotkb:UNQ310/PRO353(orf name)|uniprotkb:C1QTNF1(gene name)|psi-mi:C1QTNF1(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554116|imex:IM-24995-4100	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010183.1|sgd:S000002258|dip:DIP-3908N|mint:Q12154|ensemblfungi:YDL100C(gene)|ensemblfungi:YDL100C_mRNA(transcript)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0009408"(response to heat)|go:"GO:0010038"(response to metal ion)|go:"GO:0016787"(hydrolase activity)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043529"(GET complex)|go:"GO:0045048"(protein insertion into ER membrane)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0046872"(metal ion binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:1990507"(obsolete ATP-independent chaperone mediated protein folding)|interpro:IPR016300(Arsenite-transporting ATPase)|interpro:IPR025723|interpro:IPR027417|interpro:IPR027542|rcsb pdb:2WOJ|rcsb pdb:3A36|rcsb pdb:3A37|rcsb pdb:3B2E|rcsb pdb:3H84|rcsb pdb:3IDQ|rcsb pdb:3SJA|rcsb pdb:3SJB|rcsb pdb:3SJC|rcsb pdb:3SJD|rcsb pdb:3VLC|rcsb pdb:3ZS8|rcsb pdb:3ZS9|rcsb pdb:4PWX|rcsb pdb:4XTR|rcsb pdb:4XVU|rcsb pdb:4XWO|rcsb pdb:5BW8|rcsb pdb:5BWK	intact:EBI-750200(isoform-parent)|uniprotkb:Q9BXJ1-2(isoform-parent)	-	crc64:F795C359B5A4A461	isoform-comment:No experimental confirmation available.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:Y+PTDg+beVeCH5mn4BvWi5wBP4A559292	rogid:zxCXWIEWsl8hYnOP6DlBiu0oiNw9606	intact-crc:5A4167E300C83344|rigid:eVXYasvZvmyJ90iVGaxTTZv/h60	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q12161	uniprotkb:Q9BWC9	intact:EBI-34372|uniprotkb:D6W213|ensemblfungi:YOL054W	intact:EBI-711501|ensembl:ENSP00000309681|ensembl:ENSP00000465757|uniprotkb:Q99786|ensembl:ENSP00000466870|ensembl:ENSP00000468539|uniprotkb:B3KUF9|uniprotkb:D3K183	psi-mi:psh1_yeast(display_long)|uniprotkb:PSH1(gene name)|psi-mi:PSH1(display_short)|uniprotkb:POB3/SPT16 histone-associated protein 1(gene name synonym)|uniprotkb:O1263(orf name)|uniprotkb:YOL054W(locus name)	psi-mi:cc106_human(display_long)|uniprotkb:CCDC106(gene name)|psi-mi:CCDC106(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554112|imex:IM-24995-4099	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014587.1|sgd:S000005415|mint:Q12161|dip:DIP-6481N|ensemblfungi:YOL054W(gene)|ensemblfungi:YOL054W_mRNA(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907	ensembl:ENSG00000173581(gene)|ensembl:ENST00000308964(transcript)|ensembl:ENST00000586790(transcript)|ensembl:ENST00000588740(transcript)|ensembl:ENST00000591578(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR031591|refseq:NP_037433.2|refseq:XP_005258884.1|refseq:XP_005258885.1	-	crc64:CE0ECBCB6D465554	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:AvPMRd/GjfaTyQjEfMPhBVcvOs4559292	rogid:i15R76tObPsPuullqYoTxebAIC09606	intact-crc:1879F94408BFA8B8|rigid:Q6sxByKFDf9HnDLF5/Oba8hmifw	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9BW62	uniprotkb:P25337	intact:EBI-743591|uniprotkb:A8K5X4|ensembl:ENSP00000369989|ensembl:ENSP00000369991	intact:EBI-547|ensemblfungi:YCR063W|uniprotkb:D6VR67	psi-mi:katl1_human(display_long)|uniprotkb:p60 katanin-like 1(gene name synonym)|uniprotkb:KATNAL1(gene name)|psi-mi:KATNAL1(display_short)	psi-mi:bud31_yeast(display_long)|uniprotkb:BUD31(gene name)|psi-mi:BUD31(display_short)|uniprotkb:Bud site selection protein 31(gene name synonym)|uniprotkb:CWC14(gene name synonym)|uniprotkb:Complexed with CEF1 protein 14(gene name synonym)|uniprotkb:YCR63W(orf name)|uniprotkb:YCR903(orf name)|uniprotkb:YCR063W(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554108|imex:IM-24995-4098	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001014402.1|refseq:NP_115492.1|refseq:XP_005266631.1|ensembl:ENSG00000102781(gene)|ensembl:ENST00000380615(transcript)|ensembl:ENST00000380617(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005874"(microtubule)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008017"(microtubule binding)|go:"GO:0008568"(microtubule-severing ATPase activity)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016853"(isomerase activity)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0042802"(identical protein binding)|go:"GO:0051013"(microtubule severing)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR027417|interpro:IPR028594|interpro:IPR028596|interpro:IPR041569|rcsb pdb:6B5C	refseq:NP_009990.1|sgd:S000000659|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005686"(U2 snRNP)|interpro:IPR001748(G10 protein)|interpro:IPR018230|rcsb pdb:2MY1|ensemblfungi:YCR063W(gene)|ensemblfungi:YCR063W_mRNA(transcript)|go:"GO:0000282"(cellular bud site selection)|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|dip:DIP-1180N|mint:P25337	-	-	crc64:70A8B15F8DA6F85D	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Usi4KXsvZnNfMOGuWVSz4mfrTaE9606	rogid:DImrf7jgUrSuQtfiOvBeJr5Cl/w559292	intact-crc:70C51A35D23365AE|rigid:gvpInP+Nf6YG6/dZY+d6nRz8z3k	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9BUZ4	uniprotkb:P38340	intact:EBI-3650647|uniprotkb:O75615|uniprotkb:Q14848|uniprotkb:Q2KJU4|uniprotkb:Q2PJN8|ensembl:ENSP00000262395	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:traf4_human(display_long)|uniprotkb:TRAF4(gene name)|psi-mi:TRAF4(display_short)|uniprotkb:CART1(gene name synonym)|uniprotkb:MLN62(gene name synonym)|uniprotkb:RNF83(gene name synonym)|uniprotkb:Cysteine-rich domain associated with RING and Traf domains protein 1(gene name synonym)|uniprotkb:Metastatic lymph node gene 62 protein(gene name synonym)|uniprotkb:RING finger protein 83(gene name synonym)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554080|imex:IM-24995-4091	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004286.2|dip:DIP-40910N|ensembl:ENSG00000076604(gene)|ensembl:ENST00000262395(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006915"(apoptotic process)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030323"(respiratory tube development)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031996"(thioesterase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050699"(WW domain binding)|interpro:IPR001293(Zinc finger, TRAF-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|interpro:IPR012227(TNF receptor-associated factor TRAF)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018957|interpro:IPR027138|interpro:IPR037307|interpro:IPR043211|mint:Q9BUZ4|rcsb pdb:2EOD|rcsb pdb:2YUC|rcsb pdb:3ZJB|rcsb pdb:4K8U|rcsb pdb:4M4E|rcsb pdb:5YC1	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F	-	-	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:9Bjl/NCcleyKgZb7suHw3AVWpG09606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:8A21F71F733CABA7|rigid:IG24QeboR2KuQKIq2Km2w4i+Gto	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9BW62	uniprotkb:P38306	intact:EBI-743591|uniprotkb:A8K5X4|ensembl:ENSP00000369989|ensembl:ENSP00000369991	intact:EBI-20943|uniprotkb:D6VQJ3|ensemblfungi:YBR197C	psi-mi:katl1_human(display_long)|uniprotkb:p60 katanin-like 1(gene name synonym)|uniprotkb:KATNAL1(gene name)|psi-mi:KATNAL1(display_short)	psi-mi:yb47_yeast(display_long)|uniprotkb:YBR1409(orf name)|uniprotkb:YBR197C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554100|imex:IM-24995-4096	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001014402.1|refseq:NP_115492.1|refseq:XP_005266631.1|ensembl:ENSG00000102781(gene)|ensembl:ENST00000380615(transcript)|ensembl:ENST00000380617(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005874"(microtubule)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008017"(microtubule binding)|go:"GO:0008568"(microtubule-severing ATPase activity)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016853"(isomerase activity)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0042802"(identical protein binding)|go:"GO:0051013"(microtubule severing)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR027417|interpro:IPR028594|interpro:IPR028596|interpro:IPR041569|rcsb pdb:6B5C	sgd:S000000401|refseq:NP_009756.1|mint:P38306|dip:DIP-4258N|ensemblfungi:YBR197C(gene)|ensemblfungi:YBR197C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:Usi4KXsvZnNfMOGuWVSz4mfrTaE9606	rogid:mHsNhEvvGEIB7YFXO768m+tkHeU559292	intact-crc:89E47D2DCFCC20C6|rigid:AfadzUHZucs5QWHSQjJNH2h/fGs	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P33441	uniprotkb:Q9BW62	intact:EBI-10841|ensemblfungi:YML062C|uniprotkb:D6VZB1	intact:EBI-743591|uniprotkb:A8K5X4|ensembl:ENSP00000369989|ensembl:ENSP00000369991	psi-mi:mft1_yeast(display_long)|uniprotkb:YML062C(locus name)|uniprotkb:MFT1(gene name)|psi-mi:MFT1(display_short)|uniprotkb:Mitochondrial fusion target protein 1(gene name synonym)	psi-mi:katl1_human(display_long)|uniprotkb:p60 katanin-like 1(gene name synonym)|uniprotkb:KATNAL1(gene name)|psi-mi:KATNAL1(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554096|imex:IM-24995-4095	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0006397"(mRNA processing)|ensemblfungi:YML062C(gene)|ensemblfungi:YML062C_mRNA(transcript)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0034063"(stress granule assembly)|go:"GO:0060090"(molecular adaptor activity)|interpro:IPR008501(Protein of unknown function DUF783)|go:"GO:0000445"(THO complex part of transcription export complex)|go:"GO:0000446"(nucleoplasmic THO complex)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0006310"(DNA recombination)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|rcsb pdb:7APX|rcsb pdb:7AQO|rcsb pdb:7LUV|refseq:NP_013649.1|sgd:S000004527|mint:P33441|dip:DIP-4537N	refseq:NP_001014402.1|refseq:NP_115492.1|refseq:XP_005266631.1|ensembl:ENSG00000102781(gene)|ensembl:ENST00000380615(transcript)|ensembl:ENST00000380617(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005874"(microtubule)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008017"(microtubule binding)|go:"GO:0008568"(microtubule-severing ATPase activity)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016853"(isomerase activity)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0042802"(identical protein binding)|go:"GO:0051013"(microtubule severing)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR027417|interpro:IPR028594|interpro:IPR028596|interpro:IPR041569|rcsb pdb:6B5C	-	crc64:45A775F8C1DA3E29	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:QFj+JFK+eAlExAo8oPxdoeJOpNY559292	rogid:Usi4KXsvZnNfMOGuWVSz4mfrTaE9606	intact-crc:66486E64634A2516|rigid:vg/BvNAYp1SCVbcB+iAfapVORnk	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P53829	uniprotkb:Q9BW62	intact:EBI-28306|uniprotkb:D6W0Q5|ensemblfungi:YNL288W	intact:EBI-743591|uniprotkb:A8K5X4|ensembl:ENSP00000369989|ensembl:ENSP00000369991	psi-mi:caf40_yeast(display_long)|uniprotkb:YNL288W(locus name)|uniprotkb:N0540(orf name)|uniprotkb:40 kDa CCR4-associated factor(gene name synonym)|uniprotkb:CAF40(gene name)|psi-mi:CAF40(display_short)	psi-mi:katl1_human(display_long)|uniprotkb:p60 katanin-like 1(gene name synonym)|uniprotkb:KATNAL1(gene name)|psi-mi:KATNAL1(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554092|imex:IM-24995-4094	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014111.1|sgd:S000005232|dip:DIP-1995N|mint:P53829|ensemblfungi:YNL288W(gene)|ensemblfungi:YNL288W_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR007216(Cell differentiation, Rcd1-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:4CV5	refseq:NP_001014402.1|refseq:NP_115492.1|refseq:XP_005266631.1|ensembl:ENSG00000102781(gene)|ensembl:ENST00000380615(transcript)|ensembl:ENST00000380617(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005874"(microtubule)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008017"(microtubule binding)|go:"GO:0008568"(microtubule-severing ATPase activity)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016853"(isomerase activity)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0042802"(identical protein binding)|go:"GO:0051013"(microtubule severing)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR027417|interpro:IPR028594|interpro:IPR028596|interpro:IPR041569|rcsb pdb:6B5C	-	crc64:F3DBABE6AD3C7F3C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:etuSSgFGQOcgxPDexEXUqQg6H5s559292	rogid:Usi4KXsvZnNfMOGuWVSz4mfrTaE9606	intact-crc:06B0261C9D59059D|rigid:iztkWzEAJT7OQQ9kuB+uGAcdOOs	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9BV19	uniprotkb:P38340	intact:EBI-2874661|ensembl:ENSP00000361603	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:ca050_human(display_long)|uniprotkb:C1orf50(gene name)|psi-mi:C1orf50(display_short)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554088|imex:IM-24995-4093	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000164008(gene)|ensembl:ENST00000372525(transcript)|go:"GO:0042802"(identical protein binding)|interpro:IPR019534|refseq:NP_077002.2	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F	-	-	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:TZfvza3lr44CQW5Piu+83qv5Igo9606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:54FDF2A0298E08FA|rigid:apcvklzGvvboxdB4d6bfWHA+zIQ	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9BV19	uniprotkb:P32902	intact:EBI-2874661|ensembl:ENSP00000361603	intact:EBI-16248|ensemblfungi:YHL004W|uniprotkb:D3DKR0	psi-mi:ca050_human(display_long)|uniprotkb:C1orf50(gene name)|psi-mi:C1orf50(display_short)	psi-mi:rt04_yeast(display_long)|uniprotkb:MRP4(gene name)|psi-mi:MRP4(display_short)|uniprotkb:MRP4A(gene name synonym)|uniprotkb:Mitochondrial small ribosomal subunit protein uS2m(gene name synonym)|uniprotkb:YHL004W(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554084|imex:IM-24995-4092	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000164008(gene)|ensembl:ENST00000372525(transcript)|go:"GO:0042802"(identical protein binding)|interpro:IPR019534|refseq:NP_077002.2	ensemblfungi:YHL004W(gene)|ensemblfungi:YHL004W_mRNA(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR001865(Ribosomal protein S2)|interpro:IPR005706(Ribosomal protein S2, bacterial-type)|interpro:IPR018130|interpro:IPR023591|rcsb pdb:5MRC|rcsb pdb:5MRE|rcsb pdb:5MRF|refseq:NP_011859.1|sgd:S000000996|dip:DIP-5035N|mint:P32902	-	-	crc64:81A1CB33134BC559	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:TZfvza3lr44CQW5Piu+83qv5Igo9606	rogid:BlL3W6HUN+uAKF/AxwlV1zT5YZQ559292	intact-crc:F6EB22FA00CA1D5D|rigid:TPzZxZtze0xixf9tIGcLTCyl0wE	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q02831	uniprotkb:Q9BW62	intact:EBI-31828|uniprotkb:D6W3T9|ensemblfungi:YPL077C	intact:EBI-743591|uniprotkb:A8K5X4|ensembl:ENSP00000369989|ensembl:ENSP00000369991	psi-mi:yp077_yeast(display_long)|uniprotkb:YPL077C(locus name)	psi-mi:katl1_human(display_long)|uniprotkb:p60 katanin-like 1(gene name synonym)|uniprotkb:KATNAL1(gene name)|psi-mi:KATNAL1(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554104|imex:IM-24995-4097	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005998|refseq:NP_015248.1|dip:DIP-4022N|ensemblfungi:YPL077C(gene)|ensemblfungi:YPL077C_mRNA(transcript)	refseq:NP_001014402.1|refseq:NP_115492.1|refseq:XP_005266631.1|ensembl:ENSG00000102781(gene)|ensembl:ENST00000380615(transcript)|ensembl:ENST00000380617(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005874"(microtubule)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008017"(microtubule binding)|go:"GO:0008568"(microtubule-severing ATPase activity)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016853"(isomerase activity)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0042802"(identical protein binding)|go:"GO:0051013"(microtubule severing)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR027417|interpro:IPR028594|interpro:IPR028596|interpro:IPR041569|rcsb pdb:6B5C	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:yqOn4GWKNmFZ7UvGmyBEpgoyKlA559292	rogid:Usi4KXsvZnNfMOGuWVSz4mfrTaE9606	intact-crc:841598DEFE46D79A|rigid:2q/MAHUgYzbqg3hSIr9fvteYX7Q	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9C0F1	uniprotkb:Q12259	intact:EBI-744115|uniprotkb:A8K8W9|uniprotkb:B3KT53|uniprotkb:Q8IXZ4|uniprotkb:A8MW11|uniprotkb:D3DP42|ensembl:ENSP00000296519|ensembl:ENSP00000380009|ensembl:ENSP00000423153	intact:EBI-30776|uniprotkb:D6VYA8|ensemblfungi:YLR108C	psi-mi:cep44_human(display_long)|uniprotkb:HBV PreS1-transactivated protein 3(gene name synonym)|uniprotkb:CEP44(gene name)|psi-mi:CEP44(display_short)|uniprotkb:KIAA1712(gene name synonym)	psi-mi:yl108_yeast(display_long)|uniprotkb:L2913(orf name)|uniprotkb:YLR108C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554164|imex:IM-24995-4112	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001035247.1|refseq:NP_001138786.1|refseq:XP_011530587.1|refseq:XP_011530588.1|refseq:XP_011530589.1|refseq:XP_016864143.1|refseq:XP_016864144.1|ensembl:ENSG00000164118(gene)|ensembl:ENST00000296519(transcript)|ensembl:ENST00000396791(transcript)|ensembl:ENST00000503780(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007099"(centriole replication)|go:"GO:0008017"(microtubule binding)|go:"GO:0010457"(centriole-centriole cohesion)|go:"GO:0030496"(midbody)|interpro:IPR029157|interpro:IPR033603|mint:Q9C0F1	refseq:NP_013209.1|sgd:S000004098|dip:DIP-4075N|ensemblfungi:YLR108C(gene)|ensemblfungi:YLR108C_mRNA(transcript)|go:"GO:0005634"(nucleus)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:gDTC64oDhudGdsssC7v+suIHZkA9606	rogid:CzknxXhhvgMp3J0/oi197EgZ05U559292	intact-crc:295C7F68D4971C80|rigid:tQl1GNaqNU+YjUPEuZ8OaQB9VPM	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P21734	uniprotkb:Q9C040	intact:EBI-19717|uniprotkb:D6VSF9|ensemblfungi:YDR177W	intact:EBI-749840|uniprotkb:O60272|uniprotkb:Q9BSI9|uniprotkb:Q9UFZ1|ensembl:ENSP00000415812|ensembl:ENSP00000501586|ensembl:ENSP00000501612|ensembl:ENSP00000501652|ensembl:ENSP00000501662|ensembl:ENSP00000501792|ensembl:ENSP00000501822|ensembl:ENSP00000501951|ensembl:ENSP00000501994|ensembl:ENSP00000502089|ensembl:ENSP00000502114|ensembl:ENSP00000502159|ensembl:ENSP00000502273|ensembl:ENSP00000502348|ensembl:ENSP00000502356|ensembl:ENSP00000502519|ensembl:ENSP00000502543|ensembl:ENSP00000502676|uniprotkb:D3DP09	psi-mi:ubc1_yeast(display_long)|uniprotkb:UBC1(gene name)|psi-mi:UBC1(display_short)|uniprotkb:YDR177W(locus name)|uniprotkb:YD9395.10(orf name)|uniprotkb:Ubiquitin-protein ligase(gene name synonym)|uniprotkb:Ubiquitin carrier protein(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-24 kDa(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme 1(gene name synonym)	psi-mi:trim2_human(display_long)|uniprotkb:RING finger protein 86(gene name synonym)|uniprotkb:TRIM2(gene name)|psi-mi:TRIM2(display_short)|uniprotkb:KIAA0517(gene name synonym)|uniprotkb:RNF86(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM2(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase TRIM2(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554160|imex:IM-24995-4111	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002584|ensemblfungi:YDR177W(gene)|ensemblfungi:YDR177W_mRNA(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016050"(vesicle organization)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070628"(proteasome binding)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR009060(UBA-like)|interpro:IPR015368(Ubiquitin-conjugating enzyme, C-terminal fungi)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1FXT|rcsb pdb:1FZY|rcsb pdb:1TTE|reactome:R-SCE-8866652|reactome:R-SCE-983168|refseq:NP_010462.3|dip:DIP-6594N|mint:P21734	refseq:NP_001123539.1|refseq:NP_056086.2|ensembl:ENST00000437508(transcript)|ensembl:ENST00000674874(transcript)|ensembl:ENST00000674876(transcript)|ensembl:ENSG00000109654(gene)|refseq:XP_016863433.1|refseq:XP_016863434.1|refseq:XP_016863437.1|refseq:XP_016863438.1|refseq:XP_016863439.1|refseq:XP_016863440.1|refseq:XP_016863441.1|ensembl:ENST00000674976(transcript)|ensembl:ENST00000675054(transcript)|ensembl:ENST00000675159(transcript)|ensembl:ENST00000675293(transcript)|ensembl:ENST00000675315(transcript)|ensembl:ENST00000675384(transcript)|ensembl:ENST00000675745(transcript)|ensembl:ENST00000675835(transcript)|ensembl:ENST00000676172(transcript)|ensembl:ENST00000676252(transcript)|ensembl:ENST00000676264(transcript)|ensembl:ENST00000676348(transcript)|ensembl:ENST00000676374(transcript)|ensembl:ENST00000676423(transcript)|ensembl:ENST00000676458(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017868|interpro:IPR017907|interpro:IPR027370|mint:Q9C040|rcsb pdb:7B2R|reactome:R-HSA-877300|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001258(NHL repeat)|interpro:IPR001298(Filamin/ABP280 repeat)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR013017(NHL repeat, subgroup)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)	-	crc64:899CC397A1285145	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:3N1WHZJcgMeK0OglGpGI2m4XU8Q559292	rogid:vcyraMhX0YqrCi9PXhvlJ7QqhGs9606	intact-crc:414BB3BDA8E4FE58|rigid:U5sD2HuFEJJxijpgqcIgCEoEveU	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9C040	uniprotkb:Q12341	intact:EBI-749840|uniprotkb:O60272|uniprotkb:Q9BSI9|uniprotkb:Q9UFZ1|ensembl:ENSP00000415812|ensembl:ENSP00000501586|ensembl:ENSP00000501612|ensembl:ENSP00000501652|ensembl:ENSP00000501662|ensembl:ENSP00000501792|ensembl:ENSP00000501822|ensembl:ENSP00000501951|ensembl:ENSP00000501994|ensembl:ENSP00000502089|ensembl:ENSP00000502114|ensembl:ENSP00000502159|ensembl:ENSP00000502273|ensembl:ENSP00000502348|ensembl:ENSP00000502356|ensembl:ENSP00000502519|ensembl:ENSP00000502543|ensembl:ENSP00000502676|uniprotkb:D3DP09	intact:EBI-8176|uniprotkb:Q6Q5I5|uniprotkb:D6W411|ensemblfungi:YPL001W	psi-mi:trim2_human(display_long)|uniprotkb:RING finger protein 86(gene name synonym)|uniprotkb:TRIM2(gene name)|psi-mi:TRIM2(display_short)|uniprotkb:KIAA0517(gene name synonym)|uniprotkb:RNF86(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM2(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase TRIM2(gene name synonym)	psi-mi:hat1_yeast(display_long)|uniprotkb:LPA16W(orf name)|uniprotkb:YP8132.12(orf name)|uniprotkb:HAT1(gene name)|psi-mi:HAT1(display_short)|uniprotkb:YPL001W(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554156|imex:IM-24995-4110	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001123539.1|refseq:NP_056086.2|ensembl:ENST00000437508(transcript)|ensembl:ENST00000674874(transcript)|ensembl:ENST00000674876(transcript)|ensembl:ENSG00000109654(gene)|refseq:XP_016863433.1|refseq:XP_016863434.1|refseq:XP_016863437.1|refseq:XP_016863438.1|refseq:XP_016863439.1|refseq:XP_016863440.1|refseq:XP_016863441.1|ensembl:ENST00000674976(transcript)|ensembl:ENST00000675054(transcript)|ensembl:ENST00000675159(transcript)|ensembl:ENST00000675293(transcript)|ensembl:ENST00000675315(transcript)|ensembl:ENST00000675384(transcript)|ensembl:ENST00000675745(transcript)|ensembl:ENST00000675835(transcript)|ensembl:ENST00000676172(transcript)|ensembl:ENST00000676252(transcript)|ensembl:ENST00000676264(transcript)|ensembl:ENST00000676348(transcript)|ensembl:ENST00000676374(transcript)|ensembl:ENST00000676423(transcript)|ensembl:ENST00000676458(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017868|interpro:IPR017907|interpro:IPR027370|mint:Q9C040|rcsb pdb:7B2R|reactome:R-HSA-877300|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001258(NHL repeat)|interpro:IPR001298(Filamin/ABP280 repeat)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR013017(NHL repeat, subgroup)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)	sgd:S000005922|refseq:NP_015324.1|mint:Q12341|dip:DIP-2362N|ensemblfungi:YPL001W(gene)|ensemblfungi:YPL001W_mRNA(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003682"(chromatin binding)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006348"|go:"GO:0010485"(H4 histone acetyltransferase activity)|go:"GO:0016573"(histone acetylation)|go:"GO:0042393"(histone binding)|go:"GO:0043967"(histone H4 acetylation)|interpro:IPR000182(GCN5-related N-acetyltransferase)|interpro:IPR013523(Histone acetyltransferase HAT1, C-terminal)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR017380(Histone acetyltransferase type B, catalytic subunit)|interpro:IPR019467|interpro:IPR037113|rcsb pdb:1BOB|rcsb pdb:4PSW|rcsb pdb:4PSX|reactome:R-SCE-3214847	-	-	crc64:8DECA134274413E6	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:vcyraMhX0YqrCi9PXhvlJ7QqhGs9606	rogid:IUMaZUpA1qs4/hc8K6ezZAIpQTY559292	intact-crc:EDF9DEA61A6B4E01|rigid:IMZDvVUmODZSsGzO/6xoJIj8o9w	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9C005	intact:EBI-11522552	intact:EBI-744973|uniprotkb:D6W578|ensembl:ENSP00000295066|ensembl:ENSP00000345837	-	psi-mi:dpy30_human(display_long)|uniprotkb:DPY30(gene name)|psi-mi:DPY30(display_short)|uniprotkb:Dpy-30-like protein(gene name synonym)	psi-mi:urh1(display_short)|psi-mi:EBI-11522552(display_long)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554152|imex:IM-24995-4109	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_115963.1|ensembl:ENSG00000162961(gene)|ensembl:ENST00000295066(transcript)|ensembl:ENST00000342166(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006348"|go:"GO:0016197"(endosomal transport)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|interpro:IPR007858(Dpy-30)|interpro:IPR037856|mint:Q9C005|rcsb pdb:3G36|rcsb pdb:4RIQ|rcsb pdb:4RT4|rcsb pdb:4RTA|rcsb pdb:6E2H|rcsb pdb:6PWV|reactome:R-HSA-3214841|reactome:R-HSA-8936459|refseq:NP_001308138.1|dip:DIP-34476N	-	-	-	no-uniprot-update:	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:yC9NJhTfEIT+YyfWRSJLGbRsQkc9606	rogid:uuys9fg/B71sAw+Tb2BvegAXdp84932	intact-crc:B148D9EA1F88B571|rigid:EL2T1hfc1Qz1xHaMPIuYHKHh9+c	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9BYV6-2	uniprotkb:P38340	intact:EBI-11522718|ensembl:ENSP00000297348	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:q9byv6-2(display_long)|uniprotkb:TRIM55(gene name)|psi-mi:TRIM55(display_short)|uniprotkb:MURF2(gene name synonym)|uniprotkb:Muscle-specific RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 29(gene name synonym)|uniprotkb:RNF29(gene name synonym)|uniprotkb:p50(isoform synonym)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554128|imex:IM-24995-4103	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-2341179(isoform-parent)|uniprotkb:Q9BYV6-2(isoform-parent)|ensembl:ENSG00000147573(gene)|ensembl:ENST00000353317(transcript)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F	-	-	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:9t8UhK+Z1yBqjnQrOqPD76NuXGg9606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:833D5278C239922F|rigid:D6TuJ5LQQI7/fHckMWSouMivIz0	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P32464	uniprotkb:Q9BYV6-2	intact:EBI-8859|ensemblfungi:YKL189W|uniprotkb:D6VX11	intact:EBI-11522718|ensembl:ENSP00000297348	psi-mi:hym1_yeast(display_long)|uniprotkb:YKL189W(locus name)|uniprotkb:HYM1(gene name)|psi-mi:HYM1(display_short)	psi-mi:q9byv6-2(display_long)|uniprotkb:TRIM55(gene name)|psi-mi:TRIM55(display_short)|uniprotkb:MURF2(gene name synonym)|uniprotkb:Muscle-specific RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 29(gene name synonym)|uniprotkb:RNF29(gene name synonym)|uniprotkb:p50(isoform synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554144|imex:IM-24995-4107	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YKL189W(gene)|ensemblfungi:YKL189W_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0000920"(septum digestion after cytokinesis)|go:"GO:0005933"(cellular bud)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007118"(budding cell apical bud growth)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043332"(mating projection tip)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0044732"(mitotic spindle pole body)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013878(Mo25-like)|interpro:IPR016024(Armadillo-type fold)|reactome:R-SCE-6798695|refseq:NP_012732.1|sgd:S000001672|mint:P32464|dip:DIP-5425N	intact:EBI-2341179(isoform-parent)|uniprotkb:Q9BYV6-2(isoform-parent)|ensembl:ENSG00000147573(gene)|ensembl:ENST00000353317(transcript)	-	crc64:F48860754C892BA9	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:pOlQFFuYgFzmqf3ZGUVkBj9h7Uc559292	rogid:9t8UhK+Z1yBqjnQrOqPD76NuXGg9606	intact-crc:8503BB56BDA990F6|rigid:Q00+a0cI06mHJvICa9lINScSzyk	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q12100	uniprotkb:Q9BYV6-2	intact:EBI-36072|uniprotkb:D6VRW6|ensemblfungi:YDL025C	intact:EBI-11522718|ensembl:ENSP00000297348	psi-mi:rtk1_yeast(display_long)|uniprotkb:YDL025C(locus name)|uniprotkb:D2810(orf name)|uniprotkb:RTK1(gene name)|psi-mi:RTK1(display_short)|uniprotkb:Ribosome biogenesis and tRNA synthetase-associated kinase 1(gene name synonym)	psi-mi:q9byv6-2(display_long)|uniprotkb:TRIM55(gene name)|psi-mi:TRIM55(display_short)|uniprotkb:MURF2(gene name synonym)|uniprotkb:Muscle-specific RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 29(gene name synonym)|uniprotkb:RNF29(gene name synonym)|uniprotkb:p50(isoform synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554140|imex:IM-24995-4106	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010259.1|sgd:S000002183|dip:DIP-6483N|ensemblfungi:YDL025C(gene)|ensemblfungi:YDL025C_mRNA(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0071944"(cell periphery)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)	intact:EBI-2341179(isoform-parent)|uniprotkb:Q9BYV6-2(isoform-parent)|ensembl:ENSG00000147573(gene)|ensembl:ENST00000353317(transcript)	-	crc64:AD6160F19F3B75CF	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:XBcHXpXSRZDscEoj+hGRn4NJORE559292	rogid:9t8UhK+Z1yBqjnQrOqPD76NuXGg9606	intact-crc:DD9E6DC34497089D|rigid:qG6u9WnJpwZk5+NacyJyKRqP1tg	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9BYV6-2	uniprotkb:P38886	intact:EBI-11522718|ensembl:ENSP00000297348	intact:EBI-15949|ensemblfungi:YHR200W|uniprotkb:D3DLE9	psi-mi:q9byv6-2(display_long)|uniprotkb:TRIM55(gene name)|psi-mi:TRIM55(display_short)|uniprotkb:MURF2(gene name synonym)|uniprotkb:Muscle-specific RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 29(gene name synonym)|uniprotkb:RNF29(gene name synonym)|uniprotkb:p50(isoform synonym)	psi-mi:rpn10_yeast(display_long)|uniprotkb:RPN10(gene name)|psi-mi:RPN10(display_short)|uniprotkb:MCB1(gene name synonym)|uniprotkb:SUN1(gene name synonym)|uniprotkb:YHR200W(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554136|imex:IM-24995-4105	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-2341179(isoform-parent)|uniprotkb:Q9BYV6-2(isoform-parent)|ensembl:ENSG00000147573(gene)|ensembl:ENST00000353317(transcript)	ensemblfungi:YHR200W(gene)|ensemblfungi:YHR200W_mRNA(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|sgd:S000001243|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0036435"(K48-linked polyubiquitin modification-dependent protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043248"(proteasome assembly)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR027040|interpro:IPR036465|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5LN1|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5MPD|rcsb pdb:5MPE|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|refseq:NP_012070.3|dip:DIP-2100N|mint:P38886	-	-	crc64:8A05198B0CD7C0C3	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:9t8UhK+Z1yBqjnQrOqPD76NuXGg9606	rogid:Lg2bjPWMUcvXdLDZZMWFWyXbCcA559292	intact-crc:D2D545AF40A47D6F|rigid:YoDMoSc/LsIPVqeFajJU5v39FdY	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9BYV6-2	uniprotkb:O14468	intact:EBI-11522718|ensembl:ENSP00000297348	intact:EBI-2343965|uniprotkb:D6W304|ensemblfungi:YOR304C-A	psi-mi:q9byv6-2(display_long)|uniprotkb:TRIM55(gene name)|psi-mi:TRIM55(display_short)|uniprotkb:MURF2(gene name synonym)|uniprotkb:Muscle-specific RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 29(gene name synonym)|uniprotkb:RNF29(gene name synonym)|uniprotkb:p50(isoform synonym)	psi-mi:yo304_yeast(display_long)|uniprotkb:YOR304C-A(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554132|imex:IM-24995-4104	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-2341179(isoform-parent)|uniprotkb:Q9BYV6-2(isoform-parent)|ensembl:ENSG00000147573(gene)|ensembl:ENST00000353317(transcript)	sgd:S000005830|refseq:NP_014949.3|mint:O14468|ensemblfungi:YOR304C-A(gene)|ensemblfungi:YOR304C-A_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005933"(cellular bud)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0043332"(mating projection tip)|go:"GO:0051017"(actin filament bundle assembly)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:9t8UhK+Z1yBqjnQrOqPD76NuXGg9606	rogid:+5KU/P9FeqlhSbGhpYJ1V6DqQNg559292	intact-crc:A4B1D0C7A4DB2454|rigid:psr/fBzv8+d0CL4Ih+FUBQXeXww	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P40482	uniprotkb:Q9BYV6-2	intact:EBI-16592|ensemblfungi:YIL109C|uniprotkb:D6VVH8	intact:EBI-11522718|ensembl:ENSP00000297348	psi-mi:sec24_yeast(display_long)|uniprotkb:SEC24(gene name)|psi-mi:SEC24(display_short)|uniprotkb:Abnormal nuclear morphology 1(gene name synonym)|uniprotkb:ANU1(gene name synonym)|uniprotkb:YIL109C(locus name)	psi-mi:q9byv6-2(display_long)|uniprotkb:TRIM55(gene name)|psi-mi:TRIM55(display_short)|uniprotkb:MURF2(gene name synonym)|uniprotkb:Muscle-specific RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 29(gene name synonym)|uniprotkb:RNF29(gene name synonym)|uniprotkb:p50(isoform synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554148|imex:IM-24995-4108	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012157.3|ensemblfungi:YIL109C(gene)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016236"(macroautophagy)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0070971"(endoplasmic reticulum exit site)|ensemblfungi:YIL109C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0090110"(COPII-coated vesicle cargo loading)|interpro:IPR006895(Zinc finger, Sec23/Sec24-type)|interpro:IPR006896(Sec23/Sec24 trunk region)|interpro:IPR006900(Sec23/Sec24 helical region)|interpro:IPR007123(Gelsolin region)|interpro:IPR012990(Sec23/Sec24 beta-sandwich)|interpro:IPR029006|interpro:IPR036174|interpro:IPR036175|interpro:IPR036180|go:"GO:0000149"(SNARE binding)|go:"GO:0000329"(fungal-type vacuole membrane)|interpro:IPR036465|interpro:IPR041742|rcsb pdb:1M2V|rcsb pdb:1PCX|rcsb pdb:1PD0|rcsb pdb:1PD1|rcsb pdb:4BZI|rcsb pdb:6GNI|rcsb pdb:6ZGA|reactome:R-SCE-204005|reactome:R-SCE-5694530|reactome:R-SCE-983170|go:"GO:0005048"(signal sequence binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|sgd:S000001371|dip:DIP-2233N|mint:P40482	intact:EBI-2341179(isoform-parent)|uniprotkb:Q9BYV6-2(isoform-parent)|ensembl:ENSG00000147573(gene)|ensembl:ENST00000353317(transcript)	-	crc64:35E2BDD24CC75899	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:e7ekVFzZJMZvfRUZ9Q2jDQ/hvs0559292	rogid:9t8UhK+Z1yBqjnQrOqPD76NuXGg9606	intact-crc:DE989659C639AE0E|rigid:KagW2q0P9FpPsKOn82dMJCHzfjw	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P37263	uniprotkb:Q9H190	intact:EBI-21659|uniprotkb:D6VR87|ensemblfungi:YCR087C-A	intact:EBI-742426|ensembl:ENSP00000371233|uniprotkb:O95892|uniprotkb:Q5W0X1|uniprotkb:Q9BZ42|uniprotkb:Q9H567|uniprotkb:Q9NRY8|intact:EBI-28983470|ensembl:ENSP00000342935|ensembl:ENSP00000354013	psi-mi:yc16_yeast(display_long)|uniprotkb:YCRX16C(orf name)|uniprotkb:YCR087C-A(locus name)	psi-mi:sdcb2_human(display_long)|uniprotkb:Similar to TACIP18(gene name synonym)|uniprotkb:SDCBP2(gene name)|psi-mi:SDCBP2(display_short)|uniprotkb:SITAC18(gene name synonym)|uniprotkb:Syndecan-binding protein 2(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554212|imex:IM-24995-4124	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010011.1|sgd:S000007223|mint:P37263|dip:DIP-4536N|ensemblfungi:YCR087C-A(gene)|ensemblfungi:YCR087C-A_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR014898(Zinc finger, C2H2, LYAR-type)|interpro:IPR036236|interpro:IPR039999	refseq:NP_001186713.1|refseq:NP_056500.2|refseq:NP_536737.3|ensembl:ENSP00000342935|ensembl:ENSP00000354013|ensembl:ENST00000381808|ensembl:ENSP00000371229|ensembl:ENSP00000371233|ensembl:ENSG00000125775(gene)|ensembl:ENST00000360779(transcript)|ensembl:ENST00000381812(transcript)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007399"(nervous system development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016607"(nuclear speck)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046907"(intracellular transport)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036034|interpro:IPR041489|ensembl:ENST00000339987(transcript)	-	crc64:B5B3B4CA37B82042	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:I7iIzRqPZAKdWQSe/IeGsW0qQcU559292	rogid:vlEtVZkwLTte5PJ4i8ce+SwE/4Y9606	intact-crc:A8E7607A3F283E84|rigid:GZKCUp0YggGGRChHC1eqHtSHdEc	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P32502	uniprotkb:Q9H0E2	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	intact:EBI-74615|ensembl:ENSP00000314733|uniprotkb:Q9H9E6|uniprotkb:Q9UJ69|uniprotkb:B3KXC6	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:tolip_human(display_long)|uniprotkb:TOLLIP(gene name)|psi-mi:TOLLIP(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554208|imex:IM-24995-4123	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731	ensembl:ENSG00000078902(gene)|ensembl:ENST00000317204(transcript)|go:"GO:0005150"(interleukin-1, type I receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006914"(autophagy)|go:"GO:0007165"(signal transduction)|go:"GO:0016310"(phosphorylation)|go:"GO:0016604"(nuclear body)|go:"GO:0019900"(kinase binding)|go:"GO:0006954"(inflammatory response)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032183"(SUMO binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0035580"(specific granule lumen)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045321"(leukocyte activation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070498"(interleukin-1-mediated signaling pathway)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR009060(UBA-like)|interpro:IPR035892|interpro:IPR037301|interpro:IPR041799|rcsb pdb:1WGL|rcsb pdb:2N31|reactome:R-HSA-6798695|reactome:R-HSA-9020702|refseq:NP_061882.2|refseq:NP_001305441.1|refseq:NP_001305443.1|refseq:NP_001305444.1|refseq:NP_001305445.1|dip:DIP-30845N	-	crc64:A5409FAF1594854C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	rogid:HR6/CGVYMtuDqxW44fBD/KjScnk9606	intact-crc:80E8C6B741950B6F|rigid:10OUQ1rGrklUcPLFH/qVdVfhXPU	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9H0B3-3	uniprotkb:P53141	intact:EBI-11533070	intact:EBI-10988|ensemblfungi:YGL106W|uniprotkb:D6VU40	psi-mi:q9h0b3-3(display_long)|uniprotkb:IQCN(gene name)|psi-mi:IQCN(display_short)|uniprotkb:KIAA1683(gene name synonym)	psi-mi:mlc1_yeast(display_long)|uniprotkb:G3080(orf name)|uniprotkb:MLC1(gene name)|psi-mi:MLC1(display_short)|uniprotkb:YGL106W(locus name)|uniprotkb:Myosin-2 light chain(gene name synonym)|uniprotkb:Calmodulin-like myosin light chain MLC1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554204|imex:IM-24995-4122	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-745878(isoform-parent)	ensemblfungi:YGL106W(gene)|ensemblfungi:YGL106W_mRNA(transcript)|go:"GO:0000142"(cellular bud neck contractile ring)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005934"(cellular bud tip)|go:"GO:0006903"(vesicle targeting)|go:"GO:0016460"(myosin II complex)|go:"GO:0030427"(site of polarized growth)|go:"GO:0031489"(myosin V binding)|go:"GO:0031982"(vesicle)|go:"GO:0032038"(myosin II heavy chain binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0120155"(MIH complex)|go:"GO:1903476"(protein localization to cell division site involved in mitotic actomyosin contractile ring assembly)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|rcsb pdb:1M45|rcsb pdb:1M46|rcsb pdb:1N2D|rcsb pdb:2FCD|rcsb pdb:2FCE|reactome:R-SCE-5627123|go:"GO:0005935"(cellular bud neck)|refseq:NP_011409.1|sgd:S000003074|mint:P53141|dip:DIP-5576N	-	-	crc64:D7508123C101E4A6	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:oC4OG+AsWyQjmj2DKSPcLkrGYb89606	rogid:eC7nuA9RcHvmBgTFHG73tBQWfIY559292	intact-crc:444470F68681EDA9|rigid:jOXjZZKV7oegFRCcMw2x0MI7Ig8	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P10823	uniprotkb:Q9GZZ9	intact:EBI-7382|uniprotkb:D3DLR9|ensemblfungi:YER020W	intact:EBI-747805|uniprotkb:A6NJL3|uniprotkb:Q96ST1|uniprotkb:D3DNC8|ensembl:ENSP00000348565	psi-mi:gpa2_yeast(display_long)|uniprotkb:YER020W(locus name)|uniprotkb:GPA2(gene name)|psi-mi:GPA2(display_short)|uniprotkb:SSP101(gene name synonym)|uniprotkb:GP2-alpha(gene name synonym)	psi-mi:uba5_human(display_long)|uniprotkb:Ubiquitin-activating enzyme E1 domain-containing protein 1(gene name synonym)|uniprotkb:UFM1-activating enzyme(gene name synonym)|uniprotkb:ThiFP1(gene name synonym)|uniprotkb:UBA5(gene name)|psi-mi:UBA5(display_short)|uniprotkb:UBE1DC1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554200|imex:IM-24995-4121	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000000822|refseq:NP_010937.3|mint:P10823|dip:DIP-4346N|ensemblfungi:YER020W(gene)|ensemblfungi:YER020W_mRNA(transcript)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0007165"(signal transduction)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0008361"(regulation of cell size)|go:"GO:0009757"(hexose mediated signaling)|go:"GO:0010255"(glucose mediated signaling pathway)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0030437"(ascospore formation)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR002975(Fungal G-protein, alpha subunit)|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|reactome:R-SCE-112043|reactome:R-SCE-202040|reactome:R-SCE-399997|reactome:R-SCE-416476|reactome:R-SCE-416482|reactome:R-SCE-418592|reactome:R-SCE-434316|reactome:R-SCE-9013148	refseq:NP_079094.1|refseq:NP_938143.1|refseq:NP_001307139.1|refseq:NP_001308167.1|refseq:NP_001308168.1|ensembl:ENSG00000081307(gene)|ensembl:ENST00000356232(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030219"(megakaryocyte differentiation)|go:"GO:0032446"(protein modification by small protein conjugation)|go:"GO:0033146"(regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050905"(neuromuscular process)|go:"GO:0061709"(reticulophagy)|go:"GO:0071566"(UFM1 activating enzyme activity)|go:"GO:0071569"(protein ufmylation)|go:"GO:1990592"(protein K69-linked ufmylation)|interpro:IPR000594(UBA/THIF-type NAD/FAD binding fold)|interpro:IPR029752|interpro:IPR035985|rcsb pdb:3GUC|rcsb pdb:3H8V|rcsb pdb:5HKH|rcsb pdb:5IA8|rcsb pdb:5IAA|rcsb pdb:5L95|rcsb pdb:6H77|rcsb pdb:6H78|rcsb pdb:6H8C|reactome:R-HSA-983168	-	crc64:881B91792AE91748	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:ujQYVD/yCqR8/T2eRPygiuTD7Jg559292	rogid:qEziScb8+GA1rGAqnWD5O1w7MIg9606	intact-crc:42A0FA7573793C5A|rigid:1hPwqqR0NCPfLZp0/Inpe8QzEmk	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P43588	uniprotkb:Q9GZT8	intact:EBI-11219|uniprotkb:Q8J0T5|uniprotkb:D6VTN4|ensemblfungi:YFR004W	intact:EBI-740897|uniprotkb:Q9H2D2|uniprotkb:Q9HC18|uniprotkb:Q6X735|uniprotkb:Q53TX4|ensembl:ENSP00000386394|ensembl:ENSP00000387315|ensembl:ENSP00000498853	psi-mi:rpn11_yeast(display_long)|uniprotkb:YFR004W(locus name)|uniprotkb:RPN11(gene name)|psi-mi:RPN11(display_short)|uniprotkb:MPR1(gene name synonym)|uniprotkb:Protein MPR1(gene name synonym)|uniprotkb:26S proteasome regulatory subunit RPN11(gene name synonym)	psi-mi:nif3l_human(display_long)|uniprotkb:Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 1 protein(gene name synonym)|uniprotkb:MDS015(orf name)|uniprotkb:My018(orf name)|uniprotkb:NIF3L1(gene name)|psi-mi:NIF3L1(display_short)|uniprotkb:ALS2CR1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554196|imex:IM-24995-4120	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YFR004W(gene)|ensemblfungi:YFR004W_mRNA(transcript)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0016559"(peroxisome fission)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043248"(proteasome assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0061578"(Lys63-specific deubiquitinase activity)|go:"GO:0070628"(proteasome binding)|go:"GO:1902906"(proteasome storage granule assembly)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR024969|interpro:IPR035299|interpro:IPR037518|rcsb pdb:3J47|rcsb pdb:3JCK|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:4O8X|rcsb pdb:4O8Y|rcsb pdb:4OCL|rcsb pdb:4OCM|go:"GO:0070122"(isopeptidase activity)|rcsb pdb:4OCN|rcsb pdb:4OWP|rcsb pdb:5A5B|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5MPD|rcsb pdb:5MPE|rcsb pdb:5U4P|rcsb pdb:5W83|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-5689901|reactome:R-SCE-6798695|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|refseq:NP_116659.1|sgd:S000001900|mint:P43588|dip:DIP-1573N	refseq:NP_001129511.1|refseq:NP_001135827.1|refseq:NP_068596.2|refseq:XP_011509887.1|refseq:XP_011509884.1|refseq:XP_011509885.1|refseq:XP_011509886.1|refseq:NP_001135828.1|refseq:XP_005246799.1|refseq:XP_016860119.1|ensembl:ENSG00000196290(gene)|ensembl:ENST00000409020(transcript)|ensembl:ENST00000409357(transcript)|ensembl:ENST00000651500(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:1903507"(negative regulation of nucleic acid-templated transcription)|interpro:IPR002678(NGG1p interacting factor 3, NIF3)|interpro:IPR017222(Uncharacterised conserved protein UCP037490, NIF3, eukaryota)|interpro:IPR036069|mint:Q9GZT8	-	crc64:9DDE8BD74890894D	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:f3lAMY9siMcO2dAOfKvVrvKzfNM559292	rogid:Vvyb7CJpcwGtGAVKT2Zoqycr2yQ9606	intact-crc:B07E92A707C1AD2D|rigid:8KKyIvG5++kvD+nzm1lq/NQVyMQ	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P12612	uniprotkb:Q9C0F1	intact:EBI-19045|uniprotkb:D6VSJ6|ensemblfungi:YDR212W	intact:EBI-744115|uniprotkb:A8K8W9|uniprotkb:B3KT53|uniprotkb:Q8IXZ4|uniprotkb:A8MW11|uniprotkb:D3DP42|ensembl:ENSP00000296519|ensembl:ENSP00000380009|ensembl:ENSP00000423153	psi-mi:tcpa_yeast(display_long)|uniprotkb:TCP1(gene name)|psi-mi:TCP1(display_short)|uniprotkb:CCT1(gene name synonym)|uniprotkb:YDR212W(locus name)|uniprotkb:YD8142.13(orf name)|uniprotkb:YD8142B.04(orf name)|uniprotkb:CCT-alpha(gene name synonym)	psi-mi:cep44_human(display_long)|uniprotkb:HBV PreS1-transactivated protein 3(gene name synonym)|uniprotkb:CEP44(gene name)|psi-mi:CEP44(display_short)|uniprotkb:KIAA1712(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554168|imex:IM-24995-4113	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010498.1|sgd:S000002620|ensemblfungi:YDR212W(gene)|ensemblfungi:YDR212W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012715(T-complex protein 1, alpha subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|rcsb pdb:4V81|rcsb pdb:4V8R|rcsb pdb:4V94|rcsb pdb:5GW4|rcsb pdb:5GW5|rcsb pdb:6KRD|rcsb pdb:6KRE|rcsb pdb:6KS6|rcsb pdb:6KS7|rcsb pdb:6KS8|reactome:R-SCE-390471|reactome:R-SCE-6814122|dip:DIP-2965N|mint:P12612	refseq:NP_001035247.1|refseq:NP_001138786.1|refseq:XP_011530587.1|refseq:XP_011530588.1|refseq:XP_011530589.1|refseq:XP_016864143.1|refseq:XP_016864144.1|ensembl:ENSG00000164118(gene)|ensembl:ENST00000296519(transcript)|ensembl:ENST00000396791(transcript)|ensembl:ENST00000503780(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007099"(centriole replication)|go:"GO:0008017"(microtubule binding)|go:"GO:0010457"(centriole-centriole cohesion)|go:"GO:0030496"(midbody)|interpro:IPR029157|interpro:IPR033603|mint:Q9C0F1	-	crc64:02C625D329359E61	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:xWMsvY106Y6yQ54SOif2UlScafM559292	rogid:gDTC64oDhudGdsssC7v+suIHZkA9606	intact-crc:25D150D05E204013|rigid:/6ENGopr6rtDq1OlgLpBBq/+eik	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q08224	uniprotkb:Q9C0F1	intact:EBI-35298|uniprotkb:Q05664|uniprotkb:Q6B2F0|uniprotkb:D6W212|ensemblfungi:YOL055C	intact:EBI-744115|uniprotkb:A8K8W9|uniprotkb:B3KT53|uniprotkb:Q8IXZ4|uniprotkb:A8MW11|uniprotkb:D3DP42|ensembl:ENSP00000296519|ensembl:ENSP00000380009|ensembl:ENSP00000423153	psi-mi:thi20_yeast(display_long)|uniprotkb:THI20(gene name)|psi-mi:THI20(display_short)|uniprotkb:Hydroxymethylpyrimidine kinase(gene name synonym)|uniprotkb:YOL055C(locus name)|uniprotkb:O1239(orf name)|uniprotkb:Hydroxymethylpyrimidine phosphate kinase(gene name synonym)	psi-mi:cep44_human(display_long)|uniprotkb:HBV PreS1-transactivated protein 3(gene name synonym)|uniprotkb:CEP44(gene name)|psi-mi:CEP44(display_short)|uniprotkb:KIAA1712(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554188|imex:IM-24995-4118	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014586.1|sgd:S000005416|dip:DIP-8852N|ensemblfungi:YOL055C(gene)|ensemblfungi:YOL055C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0008902"(hydroxymethylpyrimidine kinase activity)|go:"GO:0008972"(phosphomethylpyrimidine kinase activity)|go:"GO:0009228"(thiamine biosynthetic process)|go:"GO:0009229"(thiamine diphosphate biosynthetic process)|go:"GO:0009230"(thiamine catabolic process)|go:"GO:0050334"(thiaminase activity)|interpro:IPR004305(TENA/THI-4 protein/Coenzyme PQQ biosynthesis protein C)|interpro:IPR004399(Phosphomethylpyrimidine kinase type-2)|interpro:IPR013749(Phosphomethylpyrimidine kinase type-1)|interpro:IPR016084(Haem oxygenase-like, multi-helical)|interpro:IPR027574|interpro:IPR029056|rcsb pdb:3RM5	refseq:NP_001035247.1|refseq:NP_001138786.1|refseq:XP_011530587.1|refseq:XP_011530588.1|refseq:XP_011530589.1|refseq:XP_016864143.1|refseq:XP_016864144.1|ensembl:ENSG00000164118(gene)|ensembl:ENST00000296519(transcript)|ensembl:ENST00000396791(transcript)|ensembl:ENST00000503780(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007099"(centriole replication)|go:"GO:0008017"(microtubule binding)|go:"GO:0010457"(centriole-centriole cohesion)|go:"GO:0030496"(midbody)|interpro:IPR029157|interpro:IPR033603|mint:Q9C0F1	-	crc64:D57D1C6B693EE401	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:8Z2moCtUE4aAGFn00SHe4PMjdT4559292	rogid:gDTC64oDhudGdsssC7v+suIHZkA9606	intact-crc:9E7107CA99016DEA|rigid:uD4lCFeYF3kBtM74SDEXQnnErKA	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P01097	uniprotkb:Q9C0F1	intact:EBI-8874|ensemblfungi:YDL181W|uniprotkb:D6VRH1	intact:EBI-744115|uniprotkb:A8K8W9|uniprotkb:B3KT53|uniprotkb:Q8IXZ4|uniprotkb:A8MW11|uniprotkb:D3DP42|ensembl:ENSP00000296519|ensembl:ENSP00000380009|ensembl:ENSP00000423153	psi-mi:atif_yeast(display_long)|uniprotkb:INH1(gene name)|psi-mi:INH1(display_short)|uniprotkb:ATP synthase F1 subunit epsilon(gene name synonym)|uniprotkb:D1305(orf name)|uniprotkb:YDL181W(locus name)	psi-mi:cep44_human(display_long)|uniprotkb:HBV PreS1-transactivated protein 3(gene name synonym)|uniprotkb:CEP44(gene name)|psi-mi:CEP44(display_short)|uniprotkb:KIAA1712(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554184|imex:IM-24995-4117	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YDL181W(gene)|ensemblfungi:YDL181W_mRNA(transcript)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0042030"(ATPase inhibitor activity)|interpro:IPR007648(Mitochondrial ATPase inhibitor, IATP)|rcsb pdb:3ZIA|refseq:NP_010100.1|sgd:S000002340|mint:P01097|dip:DIP-2985N	refseq:NP_001035247.1|refseq:NP_001138786.1|refseq:XP_011530587.1|refseq:XP_011530588.1|refseq:XP_011530589.1|refseq:XP_016864143.1|refseq:XP_016864144.1|ensembl:ENSG00000164118(gene)|ensembl:ENST00000296519(transcript)|ensembl:ENST00000396791(transcript)|ensembl:ENST00000503780(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007099"(centriole replication)|go:"GO:0008017"(microtubule binding)|go:"GO:0010457"(centriole-centriole cohesion)|go:"GO:0030496"(midbody)|interpro:IPR029157|interpro:IPR033603|mint:Q9C0F1	-	crc64:E1AF73A47F63CE58	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:3wsu4TOLAZdm97Kfhla8l4UKFEk559292	rogid:gDTC64oDhudGdsssC7v+suIHZkA9606	intact-crc:22F2D0322F931FD0|rigid:p+z+1wfAmX+mwOWyhlzLBKNFvtg	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q03338	uniprotkb:Q9C0F1	intact:EBI-421|uniprotkb:D6VT97|ensemblfungi:YDR473C	intact:EBI-744115|uniprotkb:A8K8W9|uniprotkb:B3KT53|uniprotkb:Q8IXZ4|uniprotkb:A8MW11|uniprotkb:D3DP42|ensembl:ENSP00000296519|ensembl:ENSP00000380009|ensembl:ENSP00000423153	psi-mi:prp3_yeast(display_long)|uniprotkb:PRP3(gene name)|psi-mi:PRP3(display_short)|uniprotkb:RNA3(gene name synonym)|uniprotkb:YDR473C(locus name)|uniprotkb:D8035.16(orf name)|uniprotkb:Pre-mRNA-splicing factor 3(gene name synonym)	psi-mi:cep44_human(display_long)|uniprotkb:HBV PreS1-transactivated protein 3(gene name synonym)|uniprotkb:CEP44(gene name)|psi-mi:CEP44(display_short)|uniprotkb:KIAA1712(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554180|imex:IM-24995-4116	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002881|refseq:NP_010761.3|ensemblfungi:YDR473C(gene)|ensemblfungi:YDR473C_mRNA(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|interpro:IPR010541(Protein of unknown function DUF1115)|interpro:IPR013881(Pre-mRNA-splicing factor 3)|interpro:IPR027104|rcsb pdb:3JCM|rcsb pdb:4YHU|rcsb pdb:4YHV|rcsb pdb:4YHW|rcsb pdb:5GAN|rcsb pdb:5GAP|rcsb pdb:5NRL|rcsb pdb:5ZWM|rcsb pdb:5ZWO|dip:DIP-5266N|mint:Q03338	refseq:NP_001035247.1|refseq:NP_001138786.1|refseq:XP_011530587.1|refseq:XP_011530588.1|refseq:XP_011530589.1|refseq:XP_016864143.1|refseq:XP_016864144.1|ensembl:ENSG00000164118(gene)|ensembl:ENST00000296519(transcript)|ensembl:ENST00000396791(transcript)|ensembl:ENST00000503780(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007099"(centriole replication)|go:"GO:0008017"(microtubule binding)|go:"GO:0010457"(centriole-centriole cohesion)|go:"GO:0030496"(midbody)|interpro:IPR029157|interpro:IPR033603|mint:Q9C0F1	-	crc64:E977FD9F708BDD91	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:KE0Y/kRXTq9LXt4PGsKnRcY7Sqg559292	rogid:gDTC64oDhudGdsssC7v+suIHZkA9606	intact-crc:010CD3A3C0B2A10C|rigid:qeZhAvTXkppjcuZ0FEe42k4EFUM	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9C0F1	uniprotkb:Q02831	intact:EBI-744115|uniprotkb:A8K8W9|uniprotkb:B3KT53|uniprotkb:Q8IXZ4|uniprotkb:A8MW11|uniprotkb:D3DP42|ensembl:ENSP00000296519|ensembl:ENSP00000380009|ensembl:ENSP00000423153	intact:EBI-31828|uniprotkb:D6W3T9|ensemblfungi:YPL077C	psi-mi:cep44_human(display_long)|uniprotkb:HBV PreS1-transactivated protein 3(gene name synonym)|uniprotkb:CEP44(gene name)|psi-mi:CEP44(display_short)|uniprotkb:KIAA1712(gene name synonym)	psi-mi:yp077_yeast(display_long)|uniprotkb:YPL077C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554176|imex:IM-24995-4115	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001035247.1|refseq:NP_001138786.1|refseq:XP_011530587.1|refseq:XP_011530588.1|refseq:XP_011530589.1|refseq:XP_016864143.1|refseq:XP_016864144.1|ensembl:ENSG00000164118(gene)|ensembl:ENST00000296519(transcript)|ensembl:ENST00000396791(transcript)|ensembl:ENST00000503780(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007099"(centriole replication)|go:"GO:0008017"(microtubule binding)|go:"GO:0010457"(centriole-centriole cohesion)|go:"GO:0030496"(midbody)|interpro:IPR029157|interpro:IPR033603|mint:Q9C0F1	sgd:S000005998|refseq:NP_015248.1|dip:DIP-4022N|ensemblfungi:YPL077C(gene)|ensemblfungi:YPL077C_mRNA(transcript)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:gDTC64oDhudGdsssC7v+suIHZkA9606	rogid:yqOn4GWKNmFZ7UvGmyBEpgoyKlA559292	intact-crc:C5C499DEE99312A8|rigid:50Q2gyGzBzcnEF7jVh1IkGQULws	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P38340	uniprotkb:Q9C0F1	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-744115|uniprotkb:A8K8W9|uniprotkb:B3KT53|uniprotkb:Q8IXZ4|uniprotkb:A8MW11|uniprotkb:D3DP42|ensembl:ENSP00000296519|ensembl:ENSP00000380009|ensembl:ENSP00000423153	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:cep44_human(display_long)|uniprotkb:HBV PreS1-transactivated protein 3(gene name synonym)|uniprotkb:CEP44(gene name)|psi-mi:CEP44(display_short)|uniprotkb:KIAA1712(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554172|imex:IM-24995-4114	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F	refseq:NP_001035247.1|refseq:NP_001138786.1|refseq:XP_011530587.1|refseq:XP_011530588.1|refseq:XP_011530589.1|refseq:XP_016864143.1|refseq:XP_016864144.1|ensembl:ENSG00000164118(gene)|ensembl:ENST00000296519(transcript)|ensembl:ENST00000396791(transcript)|ensembl:ENST00000503780(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007099"(centriole replication)|go:"GO:0008017"(microtubule binding)|go:"GO:0010457"(centriole-centriole cohesion)|go:"GO:0030496"(midbody)|interpro:IPR029157|interpro:IPR033603|mint:Q9C0F1	-	crc64:66699F37B0013088	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:gDTC64oDhudGdsssC7v+suIHZkA9606	intact-crc:7B6A55A2BFE6CE74|rigid:b9Pj/2akUY0/l21/+ZcQGgH58UM	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P47086	uniprotkb:Q9C0F1	intact:EBI-26299|uniprotkb:D6VWI7|uniprotkb:Q6Q5N5|ensemblfungi:YJR011C	intact:EBI-744115|uniprotkb:A8K8W9|uniprotkb:B3KT53|uniprotkb:Q8IXZ4|uniprotkb:A8MW11|uniprotkb:D3DP42|ensembl:ENSP00000296519|ensembl:ENSP00000380009|ensembl:ENSP00000423153	psi-mi:yjy1_yeast(display_long)|uniprotkb:J1438(orf name)|uniprotkb:YJR83.26(orf name)|uniprotkb:YJR011C(locus name)	psi-mi:cep44_human(display_long)|uniprotkb:HBV PreS1-transactivated protein 3(gene name synonym)|uniprotkb:CEP44(gene name)|psi-mi:CEP44(display_short)|uniprotkb:KIAA1712(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554192|imex:IM-24995-4119	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003772|refseq:NP_012545.1|mint:P47086|dip:DIP-5694N|ensemblfungi:YJR011C(gene)|ensemblfungi:YJR011C_mRNA(transcript)	refseq:NP_001035247.1|refseq:NP_001138786.1|refseq:XP_011530587.1|refseq:XP_011530588.1|refseq:XP_011530589.1|refseq:XP_016864143.1|refseq:XP_016864144.1|ensembl:ENSG00000164118(gene)|ensembl:ENST00000296519(transcript)|ensembl:ENST00000396791(transcript)|ensembl:ENST00000503780(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007099"(centriole replication)|go:"GO:0008017"(microtubule binding)|go:"GO:0010457"(centriole-centriole cohesion)|go:"GO:0030496"(midbody)|interpro:IPR029157|interpro:IPR033603|mint:Q9C0F1	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:b7YXohJEN6FMN8gYKAKboZQkxvQ559292	rogid:gDTC64oDhudGdsssC7v+suIHZkA9606	intact-crc:F32B515922DB709C|rigid:IlkQ17p7yZ9vPCBu6RWm03zPPBQ	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9H4P4	uniprotkb:P49723	intact:EBI-2130266|uniprotkb:B2RBT8|uniprotkb:O75598|intact:EBI-2563208|intact:EBI-11576203|uniprotkb:A6NFW0|ensembl:ENSP00000342755|ensembl:ENSP00000447303|ensembl:ENSP00000484671	intact:EBI-15251|uniprotkb:Q66R92|uniprotkb:D6VUW4|ensemblfungi:YGR180C	psi-mi:rnf41_human(display_long)|uniprotkb:RNF41(gene name)|psi-mi:RNF41(display_short)|uniprotkb:FLRF(gene name synonym)|uniprotkb:NRDP1(gene name synonym)|uniprotkb:RING finger protein 41(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase NRDP1(gene name synonym)|uniprotkb:SBBI03(orf name)	psi-mi:rir4_yeast(display_long)|uniprotkb:RNR4(gene name)|psi-mi:RNR4(display_short)|uniprotkb:YGR180C(locus name)|uniprotkb:CRT3(gene name synonym)|uniprotkb:Ribonucleotide reductase small subunit 2(gene name synonym)|uniprotkb:Ribonucleotide reductase R2 subunit 2(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554252|imex:IM-24995-4134	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011536036.1|refseq:XP_011536037.1|refseq:NP_001229755.1|refseq:NP_005776.1|refseq:NP_919340.1|refseq:NP_919339.1|refseq:XP_005268618.1|ensembl:ENSG00000181852(gene)|ensembl:ENST00000345093(transcript)|ensembl:ENST00000552656(transcript)|ensembl:ENST00000615206(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:2000377"(regulation of reactive oxygen species metabolic process)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013010(Zinc finger, SIAH-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR015036(USP8 interacting)|interpro:IPR017907|interpro:IPR037255|rcsb pdb:2FZP|rcsb pdb:2GWF|reactome:R-HSA-1358803|reactome:R-HSA-983168	sgd:S000003412|refseq:NP_011696.3|ensemblfungi:YGR180C(gene)|ensemblfungi:YGR180C_mRNA(transcript)|go:"GO:0004748"(ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005971"(ribonucleoside-diphosphate reductase complex)|go:"GO:0006260"(DNA replication)|go:"GO:0009263"(deoxyribonucleotide biosynthetic process)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR000358(Ribonucleotide reductase)|interpro:IPR012348(Ribonucleotide reductase-related)|interpro:IPR030475|interpro:IPR033909|rcsb pdb:1JK0|rcsb pdb:1SMS|rcsb pdb:1ZZD|interpro:IPR009078(Ferritin/ribonucleotide reductase-like)|dip:DIP-5381N|mint:P49723	-	-	crc64:712853F2D87D3972	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:jthVZwxUECSdqeJ2jZQ5UL28kDY9606	rogid:/Mx5xMzGpJSBsCDX8nwJMacQ6d4559292	intact-crc:111691FA3BAD73D9|rigid:5hHeel0/IkqZUsqHDInWX+FA8ZQ	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P40454	uniprotkb:Q9H257-2	intact:EBI-25278|uniprotkb:D6VVD4|ensemblfungi:YIL153W	intact:EBI-11530605|ensembl:ENSP00000360799	psi-mi:ptpa1_yeast(display_long)|uniprotkb:YIL153W(locus name)|uniprotkb:RRD1(gene name)|psi-mi:RRD1(display_short)|uniprotkb:NCS1(gene name synonym)|uniprotkb:YPA1(gene name synonym)|uniprotkb:Peptidyl-prolyl cis-trans isomerase PTPA-1(gene name synonym)|uniprotkb:Phosphotyrosyl phosphatase activator 1(gene name synonym)	psi-mi:q9h257-2(display_long)|uniprotkb:CARD9(gene name)|psi-mi:CARD9(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554248|imex:IM-24995-4133	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012113.1|sgd:S000001415|mint:P40454|dip:DIP-5663N|ensemblfungi:YIL153W(gene)|ensemblfungi:YIL153W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006914"(autophagy)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008160"(protein tyrosine phosphatase activator activity)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0043618"(regulation of transcription from RNA polymerase II promoter in response to stress)|interpro:IPR004327(Phosphotyrosyl phosphatase activator, PTPA)|interpro:IPR037218|interpro:IPR043170|rcsb pdb:2IXO|rcsb pdb:2IXP	intact:EBI-751319(isoform-parent)|uniprotkb:Q9H257-2(isoform-parent)|ensembl:ENSG00000187796(gene)|ensembl:ENST00000371734(transcript)	-	-	isoform-comment:No experimental confirmation available.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:It2q8WlpmvLEZ1fqpRF5Fypw9Q4559292	rogid:ZXH7B3K5NAzF1LZaeK50ciH1RTE9606	intact-crc:DE2C27C21B81C072|rigid:2z6QF0mbGBZcvk5p+cUtRMrS6YM	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9H257-2	uniprotkb:P40302	intact:EBI-11530605|ensembl:ENSP00000360799	intact:EBI-13955|ensemblfungi:YMR314W|uniprotkb:D6W0E1	psi-mi:q9h257-2(display_long)|uniprotkb:CARD9(gene name)|psi-mi:CARD9(display_short)	psi-mi:psa6_yeast(display_long)|uniprotkb:PRE5(gene name)|psi-mi:PRE5(display_short)|uniprotkb:YMR314W(locus name)|uniprotkb:YM9924.06(orf name)|uniprotkb:Proteasome component PRE5(gene name synonym)|uniprotkb:Macropain subunit PRE5(gene name synonym)|uniprotkb:Proteinase YSCE subunit PRE5(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit PRE5(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554244|imex:IM-24995-4132	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-751319(isoform-parent)|uniprotkb:Q9H257-2(isoform-parent)|ensembl:ENSG00000187796(gene)|ensembl:ENST00000371734(transcript)	rcsb pdb:4Y8T|rcsb pdb:4Y8U|rcsb pdb:4Y9Y|rcsb pdb:4Y9Z|rcsb pdb:4YA0|rcsb pdb:4YA1|rcsb pdb:4YA2|rcsb pdb:4YA3|rcsb pdb:4YA4|rcsb pdb:4YA5|rcsb pdb:4Y7X|rcsb pdb:4Y7Y|rcsb pdb:4Y80|rcsb pdb:4Y81|rcsb pdb:4Y82|rcsb pdb:4Y84|rcsb pdb:4Y8G|rcsb pdb:4Y8H|rcsb pdb:4Y8I|rcsb pdb:4Y8J|rcsb pdb:4Y8K|rcsb pdb:4Y8L|rcsb pdb:4Y8M|rcsb pdb:4Y8N|rcsb pdb:4Y8O|rcsb pdb:4Y8P|rcsb pdb:4Y8Q|rcsb pdb:4Y8R|rcsb pdb:4Y8S|rcsb pdb:5FG7|rcsb pdb:5FG9|rcsb pdb:5FGA|rcsb pdb:4YA7|rcsb pdb:4YA9|rcsb pdb:4Z1L|rcsb pdb:5A5B|rcsb pdb:5AHJ|rcsb pdb:5BOU|rcsb pdb:5BXL|rcsb pdb:5BXN|rcsb pdb:5CGF|rcsb pdb:5CGG|rcsb pdb:5CGH|rcsb pdb:5CGI|rcsb pdb:5CZ4|rcsb pdb:5CZ5|rcsb pdb:5CZ6|rcsb pdb:5CZ7|rcsb pdb:5CZ8|rcsb pdb:5CZ9|rcsb pdb:5CZA|rcsb pdb:5D0S|rcsb pdb:5D0T|rcsb pdb:5D0V|rcsb pdb:5D0W|rcsb pdb:5D0X|rcsb pdb:5D0Z|rcsb pdb:5DKI|rcsb pdb:5DKJ|rcsb pdb:5FGD|rcsb pdb:3HYE|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:3MG0|rcsb pdb:3MG4|rcsb pdb:3MG6|rcsb pdb:3MG7|rcsb pdb:3MG8|rcsb pdb:3NZJ|rcsb pdb:3NZW|rcsb pdb:3NZX|rcsb pdb:3OEU|rcsb pdb:3OEV|rcsb pdb:3OKJ|rcsb pdb:3SDI|rcsb pdb:3SDK|rcsb pdb:3SHJ|rcsb pdb:3TDD|rcsb pdb:3UN4|rcsb pdb:3UN8|rcsb pdb:3WXR|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:4EU2|rcsb pdb:4FZC|rcsb pdb:4FZG|rcsb pdb:4G4S|rcsb pdb:4GK7|rcsb pdb:4HNP|rcsb pdb:4HRC|rcsb pdb:4HRD|rcsb pdb:4INR|rcsb pdb:4INT|rcsb pdb:4INU|rcsb pdb:4J70|rcsb pdb:4JSQ|rcsb pdb:4JSU|rcsb pdb:4JT0|rcsb pdb:4LQI|rcsb pdb:4LTC|rcsb pdb:4NNN|rcsb pdb:4NNW|rcsb pdb:4NO1|rcsb pdb:4NO6|rcsb pdb:4NO8|rcsb pdb:4NO9|rcsb pdb:5FGE|rcsb pdb:5FGF|rcsb pdb:5FGG|rcsb pdb:5FGH|rcsb pdb:5FGI|rcsb pdb:5FHS|rcsb pdb:5JHR|rcsb pdb:5JHS|rcsb pdb:5L52|rcsb pdb:5L54|rcsb pdb:5L55|rcsb pdb:5L5A|rcsb pdb:5L5B|rcsb pdb:5L5D|rcsb pdb:5L5E|rcsb pdb:5L5F|rcsb pdb:5L5H|rcsb pdb:5L5I|rcsb pdb:5L5J|rcsb pdb:5L5O|rcsb pdb:5L5P|rcsb pdb:5L5Q|rcsb pdb:5L5R|rcsb pdb:4Q1S|rcsb pdb:4QBY|rcsb pdb:4QLQ|rcsb pdb:4QLS|rcsb pdb:4QLT|rcsb pdb:4QLU|rcsb pdb:4QLV|rcsb pdb:4QUX|rcsb pdb:4QUY|rcsb pdb:4QV0|rcsb pdb:4QV1|rcsb pdb:4QV3|rcsb pdb:4QV4|rcsb pdb:4QV5|rcsb pdb:4QV6|rcsb pdb:4QV7|rcsb pdb:4QV8|rcsb pdb:4QV9|rcsb pdb:4QVL|ensemblfungi:YMR314W(gene)|ensemblfungi:YMR314W_mRNA(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0042175"(nuclear outer membrane-endoplasmic reticulum membrane network)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR035144|rcsb pdb:1FNT|rcsb pdb:1G0U|rcsb pdb:1G65|rcsb pdb:1JD2|rcsb pdb:1RYP|rcsb pdb:1Z7Q|rcsb pdb:2F16|rcsb pdb:2FAK|rcsb pdb:2GPL|rcsb pdb:2ZCY|rcsb pdb:3BDM|rcsb pdb:3D29|rcsb pdb:3DY3|rcsb pdb:3DY4|rcsb pdb:3E47|rcsb pdb:3GPJ|rcsb pdb:3GPT|rcsb pdb:3GPW|rcsb pdb:4QVM|rcsb pdb:4QVN|rcsb pdb:4QVP|rcsb pdb:4QVQ|rcsb pdb:4QVV|rcsb pdb:4QVW|rcsb pdb:4QVY|rcsb pdb:4QW0|rcsb pdb:4QW1|rcsb pdb:4QW3|rcsb pdb:4QW4|rcsb pdb:4QW5|rcsb pdb:4QW6|rcsb pdb:4QW7|rcsb pdb:4QWF|rcsb pdb:4QWG|rcsb pdb:4QWI|rcsb pdb:4QWJ|rcsb pdb:4QWK|rcsb pdb:4QWL|rcsb pdb:4QWR|rcsb pdb:4QWS|rcsb pdb:4QWU|rcsb pdb:4QWX|rcsb pdb:4QXJ|rcsb pdb:4QZ0|rcsb pdb:4QZ1|rcsb pdb:4QZ2|rcsb pdb:4QZ3|rcsb pdb:4QZ4|rcsb pdb:4QZ5|rcsb pdb:4QZ6|rcsb pdb:4QZ7|rcsb pdb:4QZW|rcsb pdb:4QZX|rcsb pdb:4QZZ|rcsb pdb:4R00|rcsb pdb:4R02|rcsb pdb:4R17|rcsb pdb:4R18|rcsb pdb:4RUR|rcsb pdb:4V7O|rcsb pdb:4X6Z|rcsb pdb:4Y69|rcsb pdb:4Y6A|rcsb pdb:4Y6V|rcsb pdb:4Y6Z|rcsb pdb:4Y70|rcsb pdb:4Y74|rcsb pdb:4Y75|rcsb pdb:4Y77|rcsb pdb:4Y78|rcsb pdb:4Y7W|rcsb pdb:5LTT|rcsb pdb:5M2B|rcsb pdb:5MP9|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5NIF|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6G7F|rcsb pdb:6G8M|rcsb pdb:6G8N|rcsb pdb:6GOP|rcsb pdb:6H39|rcsb pdb:6HTB|rcsb pdb:6HTC|rcsb pdb:6HTD|rcsb pdb:6HTP|rcsb pdb:6HTR|rcsb pdb:6HUB|rcsb pdb:6HUC|rcsb pdb:6HUQ|rcsb pdb:6HUU|rcsb pdb:6HUV|rcsb pdb:6HV3|rcsb pdb:6HV4|rcsb pdb:6HV5|rcsb pdb:6HV7|rcsb pdb:6HVA|rcsb pdb:6HVR|rcsb pdb:6HVS|rcsb pdb:6HVT|rcsb pdb:6HVU|rcsb pdb:6HVV|rcsb pdb:5L5S|rcsb pdb:5L5T|rcsb pdb:5L5U|rcsb pdb:5L5V|rcsb pdb:5L5W|rcsb pdb:5L5X|rcsb pdb:5L5Y|rcsb pdb:5L5Z|rcsb pdb:5L60|rcsb pdb:5L61|rcsb pdb:5L62|rcsb pdb:5L63|rcsb pdb:5L64|rcsb pdb:5L65|rcsb pdb:5L66|rcsb pdb:5L67|rcsb pdb:5L68|rcsb pdb:5L69|rcsb pdb:5L6A|rcsb pdb:5L6B|rcsb pdb:5L6C|rcsb pdb:5LAI|rcsb pdb:5LAJ|rcsb pdb:6HVW|rcsb pdb:6HVX|rcsb pdb:6HVY|rcsb pdb:6HW0|rcsb pdb:6HW3|rcsb pdb:6HW4|rcsb pdb:6HW5|rcsb pdb:6HW6|rcsb pdb:6HW7|rcsb pdb:6HW8|rcsb pdb:6HW9|rcsb pdb:6HWA|rcsb pdb:6HWB|rcsb pdb:6HWC|rcsb pdb:6HWD|rcsb pdb:6HWE|rcsb pdb:6HWF|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2X|rcsb pdb:6J30|rcsb pdb:6ZOU|rcsb pdb:6ZP6|rcsb pdb:6ZP8|rcsb pdb:7LS5|rcsb pdb:7LS6|rcsb pdb:7LSX|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|rcsb pdb:6J2Q|refseq:NP_014045.1|sgd:S000004931|mint:P40302|dip:DIP-1528N	-	isoform-comment:No experimental confirmation available.	crc64:C43CBCC1C6B9E39E	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:ZXH7B3K5NAzF1LZaeK50ciH1RTE9606	rogid:C9GPb0JAklkBz0t/YYqRMNEiQss559292	intact-crc:66E148D75242B814|rigid:VeHZM7S8tZjQXJfmOgOF/t5Ecz4	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q12134	uniprotkb:Q9H190	intact:EBI-37262|uniprotkb:D6W2Y2|ensemblfungi:YOR284W	intact:EBI-742426|ensembl:ENSP00000371233|uniprotkb:O95892|uniprotkb:Q5W0X1|uniprotkb:Q9BZ42|uniprotkb:Q9H567|uniprotkb:Q9NRY8|intact:EBI-28983470|ensembl:ENSP00000342935|ensembl:ENSP00000354013	psi-mi:hua2_yeast(display_long)|uniprotkb:HUA2(gene name)|psi-mi:HUA2(display_short)|uniprotkb:YOR284W(locus name)	psi-mi:sdcb2_human(display_long)|uniprotkb:Similar to TACIP18(gene name synonym)|uniprotkb:SDCBP2(gene name)|psi-mi:SDCBP2(display_short)|uniprotkb:SITAC18(gene name synonym)|uniprotkb:Syndecan-binding protein 2(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554240|imex:IM-24995-4131	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005810|refseq:NP_014927.3|dip:DIP-1472N|ensemblfungi:YOR284W(gene)|ensemblfungi:YOR284W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)	refseq:NP_001186713.1|refseq:NP_056500.2|refseq:NP_536737.3|ensembl:ENSP00000342935|ensembl:ENSP00000354013|ensembl:ENST00000381808|ensembl:ENSP00000371229|ensembl:ENSP00000371233|ensembl:ENSG00000125775(gene)|ensembl:ENST00000360779(transcript)|ensembl:ENST00000381812(transcript)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007399"(nervous system development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016607"(nuclear speck)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046907"(intracellular transport)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036034|interpro:IPR041489|ensembl:ENST00000339987(transcript)	-	crc64:B1F3A81B7C0F65AC	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:1pZZ+nqYY1Ah7Zdeu4QP4kvKfsw559292	rogid:vlEtVZkwLTte5PJ4i8ce+SwE/4Y9606	intact-crc:E8F6FC9226ABEA4D|rigid:4ghmKfu8fA2mV/jIaTlq1waDxbs	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9H190	uniprotkb:Q12196	intact:EBI-742426|ensembl:ENSP00000371233|uniprotkb:O95892|uniprotkb:Q5W0X1|uniprotkb:Q9BZ42|uniprotkb:Q9H567|uniprotkb:Q9NRY8|intact:EBI-28983470|ensembl:ENSP00000342935|ensembl:ENSP00000354013	intact:EBI-15224|uniprotkb:Q00602|uniprotkb:D6W2H8|ensemblfungi:YOR119C	psi-mi:sdcb2_human(display_long)|uniprotkb:Similar to TACIP18(gene name synonym)|uniprotkb:SDCBP2(gene name)|psi-mi:SDCBP2(display_short)|uniprotkb:SITAC18(gene name synonym)|uniprotkb:Syndecan-binding protein 2(gene name synonym)	psi-mi:rio1_yeast(display_long)|uniprotkb:RIO1(gene name)|psi-mi:RIO1(display_short)|uniprotkb:RRP10(gene name synonym)|uniprotkb:O3266(orf name)|uniprotkb:YOR3266C(orf name)|uniprotkb:YOR119C(locus name)|uniprotkb:Ribosomal RNA-processing protein 10(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554216|imex:IM-24995-4125	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001186713.1|refseq:NP_056500.2|refseq:NP_536737.3|ensembl:ENSP00000342935|ensembl:ENSP00000354013|ensembl:ENST00000381808|ensembl:ENSP00000371229|ensembl:ENSP00000371233|ensembl:ENSG00000125775(gene)|ensembl:ENST00000360779(transcript)|ensembl:ENST00000381812(transcript)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007399"(nervous system development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016607"(nuclear speck)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046907"(intracellular transport)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036034|interpro:IPR041489|ensembl:ENST00000339987(transcript)	sgd:S000005645|reactome:R-SCE-6791226|refseq:NP_014762.3|ensemblfungi:YOR119C(gene)|ensemblfungi:YOR119C_mRNA(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0016479"(negative regulation of transcription by RNA polymerase I)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0030874"(nucleolar chromatin)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000234"(positive regulation of rRNA processing)|interpro:IPR000687(RIO kinase)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017407(Serine/threonine-protein kinase Rio1)|interpro:IPR018935|go:"GO:0030490"(maturation of SSU-rRNA)|dip:DIP-4146N	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:vlEtVZkwLTte5PJ4i8ce+SwE/4Y9606	rogid:wLf+Zbnca7AHLdHkLrakVxXltKw559292	intact-crc:D4A2ED0CA439529C|rigid:BbGHj1eDv/Y2183yBJaJc8WoQFY	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9H190	uniprotkb:P32796	intact:EBI-742426|ensembl:ENSP00000371233|uniprotkb:O95892|uniprotkb:Q5W0X1|uniprotkb:Q9BZ42|uniprotkb:Q9H567|uniprotkb:Q9NRY8|intact:EBI-28983470|ensembl:ENSP00000342935|ensembl:ENSP00000354013	intact:EBI-3935|uniprotkb:D6VZD3|ensemblfungi:YML042W	psi-mi:sdcb2_human(display_long)|uniprotkb:Similar to TACIP18(gene name synonym)|uniprotkb:SDCBP2(gene name)|psi-mi:SDCBP2(display_short)|uniprotkb:SITAC18(gene name synonym)|uniprotkb:Syndecan-binding protein 2(gene name synonym)	psi-mi:cacp_yeast(display_long)|uniprotkb:CAT2(gene name)|psi-mi:CAT2(display_short)|uniprotkb:CAT(gene name synonym)|uniprotkb:YCAT(gene name synonym)|uniprotkb:YML042W(locus name)|uniprotkb:YM8054.01(orf name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554232|imex:IM-24995-4129	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001186713.1|refseq:NP_056500.2|refseq:NP_536737.3|ensembl:ENSP00000342935|ensembl:ENSP00000354013|ensembl:ENST00000381808|ensembl:ENSP00000371229|ensembl:ENSP00000371233|ensembl:ENSG00000125775(gene)|ensembl:ENST00000360779(transcript)|ensembl:ENST00000381812(transcript)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007399"(nervous system development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016607"(nuclear speck)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046907"(intracellular transport)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036034|interpro:IPR041489|ensembl:ENST00000339987(transcript)	refseq:NP_013670.1|sgd:S000004506|dip:DIP-2476N|reactome:R-SCE-1483191|reactome:R-SCE-264642|reactome:R-SCE-389887|reactome:R-SCE-9033241|ensemblfungi:YML042W(gene)|ensemblfungi:YML042W_mRNA(transcript)|go:"GO:0004092"(carnitine O-acetyltransferase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005777"(peroxisome)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0009437"(carnitine metabolic process)|interpro:IPR000542(Acyltransferase ChoActase/COT/CPT)|interpro:IPR023213|interpro:IPR039551|interpro:IPR042231	-	-	crc64:C707BAC7ECB4D095	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:vlEtVZkwLTte5PJ4i8ce+SwE/4Y9606	rogid:2UCscm7QlYT+CY3gtU/Wg37C/+Y559292	intact-crc:232F3FB2E0AEB3F9|rigid:GebY+wTkfNrK55hJdHdAHIewoxc	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P32342	uniprotkb:Q9H190	intact:EBI-17984|uniprotkb:D6VXG8|ensemblfungi:YKL122C	intact:EBI-742426|ensembl:ENSP00000371233|uniprotkb:O95892|uniprotkb:Q5W0X1|uniprotkb:Q9BZ42|uniprotkb:Q9H567|uniprotkb:Q9NRY8|intact:EBI-28983470|ensembl:ENSP00000342935|ensembl:ENSP00000354013	psi-mi:srp21_yeast(display_long)|uniprotkb:SRP21(gene name)|psi-mi:SRP21(display_short)|uniprotkb:YKL122C(locus name)|uniprotkb:YKL527(orf name)|uniprotkb:Signal recognition particle 21 kDa protein(gene name synonym)	psi-mi:sdcb2_human(display_long)|uniprotkb:Similar to TACIP18(gene name synonym)|uniprotkb:SDCBP2(gene name)|psi-mi:SDCBP2(display_short)|uniprotkb:SITAC18(gene name synonym)|uniprotkb:Syndecan-binding protein 2(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554228|imex:IM-24995-4128	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012800.1|sgd:S000001605|ensemblfungi:YKL122C(gene)|ensemblfungi:YKL122C_mRNA(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005786"(signal recognition particle, endoplasmic reticulum targeting)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|interpro:IPR039432|reactome:R-SCE-1799339|dip:DIP-4863N|mint:P32342	refseq:NP_001186713.1|refseq:NP_056500.2|refseq:NP_536737.3|ensembl:ENSP00000342935|ensembl:ENSP00000354013|ensembl:ENST00000381808|ensembl:ENSP00000371229|ensembl:ENSP00000371233|ensembl:ENSG00000125775(gene)|ensembl:ENST00000360779(transcript)|ensembl:ENST00000381812(transcript)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007399"(nervous system development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016607"(nuclear speck)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046907"(intracellular transport)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036034|interpro:IPR041489|ensembl:ENST00000339987(transcript)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:UXyZkJvr4xO44RgYpDeA8lsND/k559292	rogid:vlEtVZkwLTte5PJ4i8ce+SwE/4Y9606	intact-crc:A032721C1E438D9C|rigid:aHpe/9H37iI703H7ZyZKFbRzWX8	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P53927	uniprotkb:Q9H190	intact:EBI-28853|uniprotkb:D6W171|ensemblfungi:YNL110C	intact:EBI-742426|ensembl:ENSP00000371233|uniprotkb:O95892|uniprotkb:Q5W0X1|uniprotkb:Q9BZ42|uniprotkb:Q9H567|uniprotkb:Q9NRY8|intact:EBI-28983470|ensembl:ENSP00000342935|ensembl:ENSP00000354013	psi-mi:nop15_yeast(display_long)|uniprotkb:YNL110C(locus name)|uniprotkb:N1954(orf name)|uniprotkb:Nucleolar protein 15(gene name synonym)|uniprotkb:NOP15(gene name)|psi-mi:NOP15(display_short)	psi-mi:sdcb2_human(display_long)|uniprotkb:Similar to TACIP18(gene name synonym)|uniprotkb:SDCBP2(gene name)|psi-mi:SDCBP2(display_short)|uniprotkb:SITAC18(gene name synonym)|uniprotkb:Syndecan-binding protein 2(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554224|imex:IM-24995-4127	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014289.1|sgd:S000005054|dip:DIP-4741N|mint:P53927|ensemblfungi:YNL110C(gene)|ensemblfungi:YNL110C_mRNA(transcript)|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0019843"(rRNA binding)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0042273"(ribosomal large subunit biogenesis)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034469|interpro:IPR035979|rcsb pdb:3JCT|rcsb pdb:5T9P|rcsb pdb:5Z3G|rcsb pdb:6C0F|rcsb pdb:6CB1|rcsb pdb:6ELZ|rcsb pdb:6EM1|rcsb pdb:6EM3|rcsb pdb:6EM4|rcsb pdb:6EM5|rcsb pdb:6M62|rcsb pdb:6YLX|rcsb pdb:6YLY|rcsb pdb:7BTB	refseq:NP_001186713.1|refseq:NP_056500.2|refseq:NP_536737.3|ensembl:ENSP00000342935|ensembl:ENSP00000354013|ensembl:ENST00000381808|ensembl:ENSP00000371229|ensembl:ENSP00000371233|ensembl:ENSG00000125775(gene)|ensembl:ENST00000360779(transcript)|ensembl:ENST00000381812(transcript)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007399"(nervous system development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016607"(nuclear speck)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046907"(intracellular transport)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036034|interpro:IPR041489|ensembl:ENST00000339987(transcript)	-	crc64:EC86E3C77C863292	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:WHuY5zx7DUsm1G+00Bc6wM8JAJc559292	rogid:vlEtVZkwLTte5PJ4i8ce+SwE/4Y9606	intact-crc:A50F74F232865C31|rigid:/s3CJWR5qBcco0QZMZrfaau1PRs	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9H190	uniprotkb:P42846	intact:EBI-742426|ensembl:ENSP00000371233|uniprotkb:O95892|uniprotkb:Q5W0X1|uniprotkb:Q9BZ42|uniprotkb:Q9H567|uniprotkb:Q9NRY8|intact:EBI-28983470|ensembl:ENSP00000342935|ensembl:ENSP00000354013	intact:EBI-28360|uniprotkb:D6W0N7|ensemblfungi:YNL308C	psi-mi:sdcb2_human(display_long)|uniprotkb:Similar to TACIP18(gene name synonym)|uniprotkb:SDCBP2(gene name)|psi-mi:SDCBP2(display_short)|uniprotkb:SITAC18(gene name synonym)|uniprotkb:Syndecan-binding protein 2(gene name synonym)	psi-mi:kri1_yeast(display_long)|uniprotkb:YNL308C(locus name)|uniprotkb:N0388(orf name)|uniprotkb:KRR1-interacting protein 1(gene name synonym)|uniprotkb:KRI1(gene name)|psi-mi:KRI1(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554220|imex:IM-24995-4126	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001186713.1|refseq:NP_056500.2|refseq:NP_536737.3|ensembl:ENSP00000342935|ensembl:ENSP00000354013|ensembl:ENST00000381808|ensembl:ENSP00000371229|ensembl:ENSP00000371233|ensembl:ENSG00000125775(gene)|ensembl:ENST00000360779(transcript)|ensembl:ENST00000381812(transcript)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007399"(nervous system development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016607"(nuclear speck)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046907"(intracellular transport)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036034|interpro:IPR041489|ensembl:ENST00000339987(transcript)	refseq:NP_014091.1|sgd:S000005252|dip:DIP-4073N|mint:P42846|ensemblfungi:YNL308C(gene)|ensemblfungi:YNL308C_mRNA(transcript)|go:"GO:0000447"("endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0005730"(nucleolus)|go:"GO:0030686"(90S preribosome)|interpro:IPR018034|interpro:IPR024626	-	-	crc64:3B637571EDB05EA6	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:vlEtVZkwLTte5PJ4i8ce+SwE/4Y9606	rogid:NhrYBQD07sx7vTVgiDFulg1FrAI559292	intact-crc:F38B69FEF48FE718|rigid:7fCfnus8xIBHPRTPaAKnPuow3RE	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9H190	uniprotkb:P33322	intact:EBI-742426|ensembl:ENSP00000371233|uniprotkb:O95892|uniprotkb:Q5W0X1|uniprotkb:Q9BZ42|uniprotkb:Q9H567|uniprotkb:Q9NRY8|intact:EBI-28983470|ensembl:ENSP00000342935|ensembl:ENSP00000354013	intact:EBI-4105|ensemblfungi:YLR175W|uniprotkb:D6VYH9	psi-mi:sdcb2_human(display_long)|uniprotkb:Similar to TACIP18(gene name synonym)|uniprotkb:SDCBP2(gene name)|psi-mi:SDCBP2(display_short)|uniprotkb:SITAC18(gene name synonym)|uniprotkb:Syndecan-binding protein 2(gene name synonym)	psi-mi:cbf5_yeast(display_long)|uniprotkb:Small nucleolar RNP protein CBF5(gene name synonym)|uniprotkb:L9470.11(orf name)|uniprotkb:YLR175W(locus name)|uniprotkb:CBF5(gene name)|psi-mi:CBF5(display_short)|uniprotkb:Centromere/microtubule-binding protein CBF5(gene name synonym)|uniprotkb:Centromere-binding factor 5(gene name synonym)|uniprotkb:H/ACA snoRNP protein CBF5(gene name synonym)|uniprotkb:p64'(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554236|imex:IM-24995-4130	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001186713.1|refseq:NP_056500.2|refseq:NP_536737.3|ensembl:ENSP00000342935|ensembl:ENSP00000354013|ensembl:ENST00000381808|ensembl:ENSP00000371229|ensembl:ENSP00000371233|ensembl:ENSG00000125775(gene)|ensembl:ENST00000360779(transcript)|ensembl:ENST00000381812(transcript)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007399"(nervous system development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016607"(nuclear speck)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046907"(intracellular transport)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036034|interpro:IPR041489|ensembl:ENST00000339987(transcript)	ensemblfungi:YLR175W(gene)|ensemblfungi:YLR175W_mRNA(transcript)|go:"GO:0000154"(rRNA modification)|go:"GO:0000495"(box H/ACA RNA 3'-end processing)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0006364"(rRNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0009982"(pseudouridine synthase activity)|go:"GO:0030686"(90S preribosome)|go:"GO:0031118"(rRNA pseudouridine synthesis)|go:"GO:0031120"(snRNA pseudouridine synthesis)|go:"GO:0031429"(box H/ACA snoRNP complex)|go:"GO:0051301"(cell division)|go:"GO:1990481"(mRNA pseudouridine synthesis)|refseq:NP_013276.1|sgd:S000004165|dip:DIP-4472N|mint:P33322|interpro:IPR002478(PUA)|interpro:IPR002501(tRNA pseudouridine synthase B, N-terminal)|interpro:IPR004521(Uncharacterized domain 2)|interpro:IPR004802(Putative rRNA pseudouridine synthase)|interpro:IPR012960(DKCLD)|interpro:IPR015947(PUA-like)|interpro:IPR020103|interpro:IPR032819|interpro:IPR036974|rcsb pdb:3U28|rcsb pdb:3UAI|rcsb pdb:3ZV0|reactome:R-SCE-171319	-	-	crc64:D356B39FDCC32E2D	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:vlEtVZkwLTte5PJ4i8ce+SwE/4Y9606	rogid:cBheN/I3bpmiXhl3cWX8OT/YWco559292	intact-crc:D61F0500A6A0623F|rigid:4zkyrwd7cHP1mj/wDfoxx/iBTEU	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P32502	uniprotkb:Q9H773	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	intact:EBI-723569|intact:EBI-1384169|ensembl:ENSP00000322524	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:dctp1_human(display_long)|uniprotkb:DCTPP1(gene name)|psi-mi:DCTPP1(display_short)|uniprotkb:RS21C6(gene name synonym)|uniprotkb:CDA03(orf name)|uniprotkb:XTP3TPA(gene name synonym)|uniprotkb:Deoxycytidine-triphosphatase 1(gene name synonym)|uniprotkb:XTP3-transactivated gene A protein(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554260|imex:IM-24995-4136	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731	refseq:NP_077001.1|ensembl:ENST00000319285(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006253"(dCTP catabolic process)|go:"GO:0009143"(nucleoside triphosphate catabolic process)|go:"GO:0032556"(pyrimidine deoxyribonucleotide binding)|go:"GO:0042262"(DNA protection)|go:"GO:0042802"(identical protein binding)|go:"GO:0047429"(nucleoside-triphosphate diphosphatase activity)|go:"GO:0047840"(dCTP diphosphatase activity)|interpro:IPR025984|mint:Q9H773|reactome:R-HSA-499943|ensembl:ENSG00000179958(gene)	-	crc64:A5409FAF1594854C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	rogid:4EfV2ZU2MgDiFXShthfualZnat09606	intact-crc:2B96C64FDD23D0C2|rigid:prSEHirUfm6oCGHNCI6tZroyySY	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9H6J7-4	uniprotkb:Q12071	intact:EBI-11536490|ensembl:ENSP00000367881	intact:EBI-36751|uniprotkb:D6VS12|ensemblfungi:YDR027C	psi-mi:q9h6j7-4(display_long)|uniprotkb:C11orf49(gene name)|psi-mi:C11orf49(display_short)	psi-mi:vps54_yeast(display_long)|uniprotkb:VPS54(gene name)|psi-mi:VPS54(display_short)|uniprotkb:CGP1(gene name synonym)|uniprotkb:CPF1 genetically-interacting protein 1(gene name synonym)|uniprotkb:Temperature-sensitive clathrin synthetic mutation protein 3(gene name synonym)|uniprotkb:LUV1(gene name synonym)|uniprotkb:RKI1(gene name synonym)|uniprotkb:TCS3(gene name synonym)|uniprotkb:YDR027C(locus name)|uniprotkb:PZF889(orf name)|uniprotkb:YD9813.05C(orf name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554256|imex:IM-24995-4135	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-721300(isoform-parent)|ensembl:ENSG00000149179(gene)|ensembl:ENST00000378618(transcript)	refseq:NP_010310.1|sgd:S000002434|mint:Q12071|dip:DIP-5903N|ensemblfungi:YDR027C(gene)|ensemblfungi:YDR027C_mRNA(transcript)|go:"GO:0000938"(GARP complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030476"(ascospore wall assembly)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0090156"(cellular sphingolipid homeostasis)|interpro:IPR039745	-	isoform-comment:No experimental confirmation available.	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:IXWzzwfToJyIlZmm7FsAk7WFslY9606	rogid:zouXMNMGbIJwjId/O7zsCZccY90559292	intact-crc:91280798FF44C1A7|rigid:QA97QFpcKzHeViAEcPx06mRXIoQ	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q12161	uniprotkb:Q9H9D4	intact:EBI-34372|uniprotkb:D6W213|ensemblfungi:YOL054W	intact:EBI-347633|ensembl:ENSP00000309606	psi-mi:psh1_yeast(display_long)|uniprotkb:PSH1(gene name)|psi-mi:PSH1(display_short)|uniprotkb:POB3/SPT16 histone-associated protein 1(gene name synonym)|uniprotkb:O1263(orf name)|uniprotkb:YOL054W(locus name)	psi-mi:zn408_human(display_long)|uniprotkb:ZNF408(gene name)|psi-mi:ZNF408(display_short)|uniprotkb:PFM14(gene name synonym)|uniprotkb:PRDM17(gene name synonym)|uniprotkb:PR domain zinc finger protein 17(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554288|imex:IM-24995-4143	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014587.1|sgd:S000005415|mint:Q12161|dip:DIP-6481N|ensemblfungi:YOL054W(gene)|ensemblfungi:YOL054W_mRNA(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907	refseq:NP_001171680.1|refseq:NP_079017.1|ensembl:ENSG00000175213(gene)|ensembl:ENST00000311764(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR044412	-	crc64:CE0ECBCB6D465554	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:AvPMRd/GjfaTyQjEfMPhBVcvOs4559292	rogid:VYheZbRzNxXoFvtRSwYv//yTtOU9606	intact-crc:91734BFDF91F555A|rigid:TLsLvV1Wg8fZQazeThoTw+yKyxE	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P25044	uniprotkb:Q9H972-2	intact:EBI-14183|ensemblfungi:YDL230W|uniprotkb:D6VRC6	intact:EBI-11524174|ensembl:ENSP00000341353	psi-mi:ptp1_yeast(display_long)|uniprotkb:Protein-tyrosine phosphatase 1(gene name synonym)|uniprotkb:PTP1(gene name)|psi-mi:PTP1(display_short)|uniprotkb:YDL230W(locus name)	psi-mi:q9h972-2(display_long)|uniprotkb:C14orf93(gene name)|psi-mi:C14orf93(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554284|imex:IM-24995-4142	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010051.1|sgd:S000002389|ensemblfungi:YDL230W(gene)|ensemblfungi:YDL230W_mRNA(transcript)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007124"(pseudohyphal growth)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR016277(Non-receptor tyrosine-protein phosphatase type 1, yeast)|interpro:IPR029021|go:"GO:0005737"(cytoplasm)|dip:DIP-2765N|reactome:R-SCE-6798695	intact:EBI-10329620(isoform-parent)|ensembl:ENSG00000100802(gene)|ensembl:ENST00000341470(transcript)|uniprotkb:Q9H972-2(isoform-parent)	-	crc64:15F71E50694BE562	isoform-comment:No experimental confirmation available.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:uQd7Homoz5Z834hLaSgQssol+EE559292	rogid:78CwgvNc8HhvQM4urISJ8VU88BU9606	intact-crc:EE24AB9747D5669C|rigid:BlfdJ2WU+yBQv0fitvOxz4ATEXg	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P40302	uniprotkb:Q9H773	intact:EBI-13955|ensemblfungi:YMR314W|uniprotkb:D6W0E1	intact:EBI-723569|intact:EBI-1384169|ensembl:ENSP00000322524	psi-mi:psa6_yeast(display_long)|uniprotkb:PRE5(gene name)|psi-mi:PRE5(display_short)|uniprotkb:YMR314W(locus name)|uniprotkb:YM9924.06(orf name)|uniprotkb:Proteasome component PRE5(gene name synonym)|uniprotkb:Macropain subunit PRE5(gene name synonym)|uniprotkb:Proteinase YSCE subunit PRE5(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit PRE5(gene name synonym)	psi-mi:dctp1_human(display_long)|uniprotkb:DCTPP1(gene name)|psi-mi:DCTPP1(display_short)|uniprotkb:RS21C6(gene name synonym)|uniprotkb:CDA03(orf name)|uniprotkb:XTP3TPA(gene name synonym)|uniprotkb:Deoxycytidine-triphosphatase 1(gene name synonym)|uniprotkb:XTP3-transactivated gene A protein(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554264|imex:IM-24995-4137	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:4Y8T|rcsb pdb:4Y8U|rcsb pdb:4Y9Y|rcsb pdb:4Y9Z|rcsb pdb:4YA0|rcsb pdb:4YA1|rcsb pdb:4YA2|rcsb pdb:4YA3|rcsb pdb:4YA4|rcsb pdb:4YA5|rcsb pdb:4Y7X|rcsb pdb:4Y7Y|rcsb pdb:4Y80|rcsb pdb:4Y81|rcsb pdb:4Y82|rcsb pdb:4Y84|rcsb pdb:4Y8G|rcsb pdb:4Y8H|rcsb pdb:4Y8I|rcsb pdb:4Y8J|rcsb pdb:4Y8K|rcsb pdb:4Y8L|rcsb pdb:4Y8M|rcsb pdb:4Y8N|rcsb pdb:4Y8O|rcsb pdb:4Y8P|rcsb pdb:4Y8Q|rcsb pdb:4Y8R|rcsb pdb:4Y8S|rcsb pdb:5FG7|rcsb pdb:5FG9|rcsb pdb:5FGA|rcsb pdb:4YA7|rcsb pdb:4YA9|rcsb pdb:4Z1L|rcsb pdb:5A5B|rcsb pdb:5AHJ|rcsb pdb:5BOU|rcsb pdb:5BXL|rcsb pdb:5BXN|rcsb pdb:5CGF|rcsb pdb:5CGG|rcsb pdb:5CGH|rcsb pdb:5CGI|rcsb pdb:5CZ4|rcsb pdb:5CZ5|rcsb pdb:5CZ6|rcsb pdb:5CZ7|rcsb pdb:5CZ8|rcsb pdb:5CZ9|rcsb pdb:5CZA|rcsb pdb:5D0S|rcsb pdb:5D0T|rcsb pdb:5D0V|rcsb pdb:5D0W|rcsb pdb:5D0X|rcsb pdb:5D0Z|rcsb pdb:5DKI|rcsb pdb:5DKJ|rcsb pdb:5FGD|rcsb pdb:3HYE|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:3MG0|rcsb pdb:3MG4|rcsb pdb:3MG6|rcsb pdb:3MG7|rcsb pdb:3MG8|rcsb pdb:3NZJ|rcsb pdb:3NZW|rcsb pdb:3NZX|rcsb pdb:3OEU|rcsb pdb:3OEV|rcsb pdb:3OKJ|rcsb pdb:3SDI|rcsb pdb:3SDK|rcsb pdb:3SHJ|rcsb pdb:3TDD|rcsb pdb:3UN4|rcsb pdb:3UN8|rcsb pdb:3WXR|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:4EU2|rcsb pdb:4FZC|rcsb pdb:4FZG|rcsb pdb:4G4S|rcsb pdb:4GK7|rcsb pdb:4HNP|rcsb pdb:4HRC|rcsb pdb:4HRD|rcsb pdb:4INR|rcsb pdb:4INT|rcsb pdb:4INU|rcsb pdb:4J70|rcsb pdb:4JSQ|rcsb pdb:4JSU|rcsb pdb:4JT0|rcsb pdb:4LQI|rcsb pdb:4LTC|rcsb pdb:4NNN|rcsb pdb:4NNW|rcsb pdb:4NO1|rcsb pdb:4NO6|rcsb pdb:4NO8|rcsb pdb:4NO9|rcsb pdb:5FGE|rcsb pdb:5FGF|rcsb pdb:5FGG|rcsb pdb:5FGH|rcsb pdb:5FGI|rcsb pdb:5FHS|rcsb pdb:5JHR|rcsb pdb:5JHS|rcsb pdb:5L52|rcsb pdb:5L54|rcsb pdb:5L55|rcsb pdb:5L5A|rcsb pdb:5L5B|rcsb pdb:5L5D|rcsb pdb:5L5E|rcsb pdb:5L5F|rcsb pdb:5L5H|rcsb pdb:5L5I|rcsb pdb:5L5J|rcsb pdb:5L5O|rcsb pdb:5L5P|rcsb pdb:5L5Q|rcsb pdb:5L5R|rcsb pdb:4Q1S|rcsb pdb:4QBY|rcsb pdb:4QLQ|rcsb pdb:4QLS|rcsb pdb:4QLT|rcsb pdb:4QLU|rcsb pdb:4QLV|rcsb pdb:4QUX|rcsb pdb:4QUY|rcsb pdb:4QV0|rcsb pdb:4QV1|rcsb pdb:4QV3|rcsb pdb:4QV4|rcsb pdb:4QV5|rcsb pdb:4QV6|rcsb pdb:4QV7|rcsb pdb:4QV8|rcsb pdb:4QV9|rcsb pdb:4QVL|ensemblfungi:YMR314W(gene)|ensemblfungi:YMR314W_mRNA(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0042175"(nuclear outer membrane-endoplasmic reticulum membrane network)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR035144|rcsb pdb:1FNT|rcsb pdb:1G0U|rcsb pdb:1G65|rcsb pdb:1JD2|rcsb pdb:1RYP|rcsb pdb:1Z7Q|rcsb pdb:2F16|rcsb pdb:2FAK|rcsb pdb:2GPL|rcsb pdb:2ZCY|rcsb pdb:3BDM|rcsb pdb:3D29|rcsb pdb:3DY3|rcsb pdb:3DY4|rcsb pdb:3E47|rcsb pdb:3GPJ|rcsb pdb:3GPT|rcsb pdb:3GPW|rcsb pdb:4QVM|rcsb pdb:4QVN|rcsb pdb:4QVP|rcsb pdb:4QVQ|rcsb pdb:4QVV|rcsb pdb:4QVW|rcsb pdb:4QVY|rcsb pdb:4QW0|rcsb pdb:4QW1|rcsb pdb:4QW3|rcsb pdb:4QW4|rcsb pdb:4QW5|rcsb pdb:4QW6|rcsb pdb:4QW7|rcsb pdb:4QWF|rcsb pdb:4QWG|rcsb pdb:4QWI|rcsb pdb:4QWJ|rcsb pdb:4QWK|rcsb pdb:4QWL|rcsb pdb:4QWR|rcsb pdb:4QWS|rcsb pdb:4QWU|rcsb pdb:4QWX|rcsb pdb:4QXJ|rcsb pdb:4QZ0|rcsb pdb:4QZ1|rcsb pdb:4QZ2|rcsb pdb:4QZ3|rcsb pdb:4QZ4|rcsb pdb:4QZ5|rcsb pdb:4QZ6|rcsb pdb:4QZ7|rcsb pdb:4QZW|rcsb pdb:4QZX|rcsb pdb:4QZZ|rcsb pdb:4R00|rcsb pdb:4R02|rcsb pdb:4R17|rcsb pdb:4R18|rcsb pdb:4RUR|rcsb pdb:4V7O|rcsb pdb:4X6Z|rcsb pdb:4Y69|rcsb pdb:4Y6A|rcsb pdb:4Y6V|rcsb pdb:4Y6Z|rcsb pdb:4Y70|rcsb pdb:4Y74|rcsb pdb:4Y75|rcsb pdb:4Y77|rcsb pdb:4Y78|rcsb pdb:4Y7W|rcsb pdb:5LTT|rcsb pdb:5M2B|rcsb pdb:5MP9|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5NIF|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6G7F|rcsb pdb:6G8M|rcsb pdb:6G8N|rcsb pdb:6GOP|rcsb pdb:6H39|rcsb pdb:6HTB|rcsb pdb:6HTC|rcsb pdb:6HTD|rcsb pdb:6HTP|rcsb pdb:6HTR|rcsb pdb:6HUB|rcsb pdb:6HUC|rcsb pdb:6HUQ|rcsb pdb:6HUU|rcsb pdb:6HUV|rcsb pdb:6HV3|rcsb pdb:6HV4|rcsb pdb:6HV5|rcsb pdb:6HV7|rcsb pdb:6HVA|rcsb pdb:6HVR|rcsb pdb:6HVS|rcsb pdb:6HVT|rcsb pdb:6HVU|rcsb pdb:6HVV|rcsb pdb:5L5S|rcsb pdb:5L5T|rcsb pdb:5L5U|rcsb pdb:5L5V|rcsb pdb:5L5W|rcsb pdb:5L5X|rcsb pdb:5L5Y|rcsb pdb:5L5Z|rcsb pdb:5L60|rcsb pdb:5L61|rcsb pdb:5L62|rcsb pdb:5L63|rcsb pdb:5L64|rcsb pdb:5L65|rcsb pdb:5L66|rcsb pdb:5L67|rcsb pdb:5L68|rcsb pdb:5L69|rcsb pdb:5L6A|rcsb pdb:5L6B|rcsb pdb:5L6C|rcsb pdb:5LAI|rcsb pdb:5LAJ|rcsb pdb:6HVW|rcsb pdb:6HVX|rcsb pdb:6HVY|rcsb pdb:6HW0|rcsb pdb:6HW3|rcsb pdb:6HW4|rcsb pdb:6HW5|rcsb pdb:6HW6|rcsb pdb:6HW7|rcsb pdb:6HW8|rcsb pdb:6HW9|rcsb pdb:6HWA|rcsb pdb:6HWB|rcsb pdb:6HWC|rcsb pdb:6HWD|rcsb pdb:6HWE|rcsb pdb:6HWF|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2X|rcsb pdb:6J30|rcsb pdb:6ZOU|rcsb pdb:6ZP6|rcsb pdb:6ZP8|rcsb pdb:7LS5|rcsb pdb:7LS6|rcsb pdb:7LSX|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|rcsb pdb:6J2Q|refseq:NP_014045.1|sgd:S000004931|mint:P40302|dip:DIP-1528N	refseq:NP_077001.1|ensembl:ENST00000319285(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006253"(dCTP catabolic process)|go:"GO:0009143"(nucleoside triphosphate catabolic process)|go:"GO:0032556"(pyrimidine deoxyribonucleotide binding)|go:"GO:0042262"(DNA protection)|go:"GO:0042802"(identical protein binding)|go:"GO:0047429"(nucleoside-triphosphate diphosphatase activity)|go:"GO:0047840"(dCTP diphosphatase activity)|interpro:IPR025984|mint:Q9H773|reactome:R-HSA-499943|ensembl:ENSG00000179958(gene)	-	crc64:C43CBCC1C6B9E39E	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:C9GPb0JAklkBz0t/YYqRMNEiQss559292	rogid:4EfV2ZU2MgDiFXShthfualZnat09606	intact-crc:078E42AC57488731|rigid:mfoAdWwBictblqsBI2yhgBhCIQQ	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9H898-2	uniprotkb:P38732	intact:EBI-11529334|ensembl:ENSP00000319785	intact:EBI-24379|uniprotkb:D3DKT0|ensemblfungi:YHL039W	psi-mi:q9h898-2(display_long)|uniprotkb:ZMAT4(gene name)|psi-mi:ZMAT4(display_short)	psi-mi:efm1_yeast(display_long)|uniprotkb:EFM1(gene name)|psi-mi:EFM1(display_short)|uniprotkb:Elongation factor methyltransferase 1(gene name synonym)|uniprotkb:YHL039W(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554276|imex:IM-24995-4140	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000165061(gene)|ensembl:ENST00000315769(transcript)|intact:EBI-2548542(isoform-parent)|uniprotkb:Q9H898-2(isoform-parent)	refseq:NP_011824.1|sgd:S000001031|dip:DIP-6582N|mint:P38732|ensemblfungi:YHL039W(gene)|ensemblfungi:YHL039W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0018026"(peptidyl-lysine monomethylation)|go:"GO:0018027"(peptidyl-lysine dimethylation)|interpro:IPR001214(SET)|interpro:IPR017119(Ribosomal lysine methyltransferase 1)|interpro:IPR044432	-	-	crc64:84BC2D3A204D9D29	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:LOS8TGoD/X97NtzSXSQ3uppdS6s9606	rogid:e5E4ijHZAIzzKWrxCzPqifR2v8U559292	intact-crc:07A9F643C774295A|rigid:yR7MxZvdtOouBGQrd9CwGxb10Ro	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9H898-2	uniprotkb:P53202	intact:EBI-11529334|ensembl:ENSP00000319785	intact:EBI-23065|uniprotkb:D6VUE0|ensemblfungi:YGR003W	psi-mi:q9h898-2(display_long)|uniprotkb:ZMAT4(gene name)|psi-mi:ZMAT4(display_short)	psi-mi:cul3_yeast(display_long)|uniprotkb:CUL3(gene name)|psi-mi:CUL3(display_short)|uniprotkb:Cullin-B(gene name synonym)|uniprotkb:YGR003W(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554272|imex:IM-24995-4139	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000165061(gene)|ensembl:ENST00000315769(transcript)|intact:EBI-2548542(isoform-parent)|uniprotkb:Q9H898-2(isoform-parent)	refseq:NP_011517.1|sgd:S000003235|dip:DIP-5506N|mint:P53202|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|ensemblfungi:YGR003W(gene)|ensemblfungi:YGR003W_mRNA(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:LOS8TGoD/X97NtzSXSQ3uppdS6s9606	rogid:FvYjEpmLA9mF35UTi97nLZwp0eE559292	intact-crc:4D8E190564FD3E28|rigid:vDYwV4mPVgbNuC6HBYVnBl6io+E	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P32902	uniprotkb:Q9H892-2	intact:EBI-16248|ensemblfungi:YHL004W|uniprotkb:D3DKR0	intact:EBI-10274410|ensembl:ENSP00000315160|ensembl:ENSP00000435291	psi-mi:rt04_yeast(display_long)|uniprotkb:MRP4(gene name)|psi-mi:MRP4(display_short)|uniprotkb:MRP4A(gene name synonym)|uniprotkb:Mitochondrial small ribosomal subunit protein uS2m(gene name synonym)|uniprotkb:YHL004W(locus name)	psi-mi:q9h892-2(display_long)|uniprotkb:TTC12(gene name)|psi-mi:TTC12(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554268|imex:IM-24995-4138	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YHL004W(gene)|ensemblfungi:YHL004W_mRNA(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR001865(Ribosomal protein S2)|interpro:IPR005706(Ribosomal protein S2, bacterial-type)|interpro:IPR018130|interpro:IPR023591|rcsb pdb:5MRC|rcsb pdb:5MRE|rcsb pdb:5MRF|refseq:NP_011859.1|sgd:S000000996|dip:DIP-5035N|mint:P32902	ensembl:ENSG00000149292(gene)|ensembl:ENST00000314756(transcript)|ensembl:ENST00000494714(transcript)|intact:EBI-2548354(isoform-parent)|uniprotkb:Q9H892-2(isoform-parent)	-	crc64:81A1CB33134BC559	isoform-comment:May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:BlL3W6HUN+uAKF/AxwlV1zT5YZQ559292	rogid:OEjSVGC92wY/pn1l/B1t3wDa3s89606	intact-crc:6C8672EF93EB2A9A|rigid:zk8lMiY4sUBQ9FH8bwjlD/O+26U	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q01976	uniprotkb:Q9H8Y8	intact:EBI-2344265|uniprotkb:D6VQB0|ensemblfungi:YBR111C	intact:EBI-739467|uniprotkb:Q96I74|uniprotkb:Q96K84|uniprotkb:Q9H946|uniprotkb:Q9UFW4|uniprotkb:Q53TE3|intact:EBI-28970723|uniprotkb:B4DKT0|ensembl:ENSP00000234160	psi-mi:adpp_yeast(display_long)|uniprotkb:YSA1(gene name)|psi-mi:YSA1(display_short)|uniprotkb:ADP-ribose diphosphatase(gene name synonym)|uniprotkb:Adenosine diphosphoribose pyrophosphatase(gene name synonym)|uniprotkb:ADP-ribose phosphohydrolase(gene name synonym)|uniprotkb:YBR0907(orf name)|uniprotkb:YBR111C(locus name)	psi-mi:gors2_human(display_long)|uniprotkb:GORASP2(gene name)|psi-mi:GORASP2(display_short)|uniprotkb:Golgi reassembly-stacking protein of 55 kDa(gene name synonym)|uniprotkb:p59(gene name synonym)|uniprotkb:Golgi phosphoprotein 6(gene name synonym)|uniprotkb:GOLPH6(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554280|imex:IM-24995-4141	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009669.1|sgd:S000000315|interpro:IPR020084|interpro:IPR000086(NUDIX hydrolase, core)|interpro:IPR015797(NUDIX)|reactome:R-SCE-2393930|ensemblfungi:YBR111C(gene)|ensemblfungi:YBR111C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006753"(nucleoside phosphate metabolic process)|go:"GO:0019693"(ribose phosphate metabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0047631"(ADP-ribose diphosphatase activity)	ensembl:ENSP00000234160|refseq:NP_001188357.1|refseq:NP_056345.3|refseq:XP_006712471.1|ensembl:ENSG00000115806(gene)|ensembl:ENST00000234160(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006996"(organelle organization)|go:"GO:0007030"(Golgi organization)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016020"(membrane)|go:"GO:0030154"(cell differentiation)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0061951"(establishment of protein localization to plasma membrane)|go:"GO:0070925"(organelle assembly)|interpro:IPR007583(GRASP55/65)|interpro:IPR024958|interpro:IPR036034|mint:Q9H8Y8|rcsb pdb:3RLE|rcsb pdb:4EDJ|reactome:R-HSA-162658	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:tpdVT9ttt/pL+UevSr0zW+rfyIc559292	rogid:xSy3HsObmteg/doer5eLoZiz+fU9606	intact-crc:BD1C9EAA24214418|rigid:OHa3n2x9t+6nqKgGZYVRAB//z5Q	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9HCK0	uniprotkb:Q12306	intact:EBI-3918996|ensembl:ENSP00000362758|ensembl:ENSP00000362760|uniprotkb:B3KQ53|uniprotkb:Q8WTR1	intact:EBI-17490|uniprotkb:D6VTD1|ensemblfungi:YDR510W	psi-mi:zbt26_human(display_long)|uniprotkb:ZBTB26(gene name)|psi-mi:ZBTB26(display_short)|uniprotkb:KIAA1572(gene name synonym)|uniprotkb:ZNF481(gene name synonym)|uniprotkb:Zinc finger protein 481(gene name synonym)|uniprotkb:Zinc finger protein Bioref(gene name synonym)	psi-mi:smt3_yeast(display_long)|uniprotkb:SMT3(gene name)|psi-mi:SMT3(display_short)|uniprotkb:D9719.15(orf name)|uniprotkb:YDR510W(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554336|imex:IM-24995-4155	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000171448(gene)|ensembl:ENST00000373654(transcript)|ensembl:ENST00000373656(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|refseq:NP_001291292.1|refseq:NP_001291293.1|refseq:NP_065975.1	refseq:NP_010798.1|sgd:S000002918|ensemblfungi:YDR510W(gene)|ensemblfungi:YDR510W_mRNA(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005940"(septin ring)|go:"GO:0016925"(protein sumoylation)|go:"GO:0031386"(protein tag)|go:"GO:0042802"(identical protein binding)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR022617|interpro:IPR029071|rcsb pdb:1EUV|rcsb pdb:1L2N|rcsb pdb:2EKE|rcsb pdb:3PGE|rcsb pdb:3QHT|rcsb pdb:3TIX|rcsb pdb:3UF8|rcsb pdb:3UQA|rcsb pdb:3UQB|rcsb pdb:3V60|rcsb pdb:3V61|rcsb pdb:3V62|rcsb pdb:3VAW|rcsb pdb:4FN2|rcsb pdb:4G50|rcsb pdb:4GGQ|rcsb pdb:4GIV|rcsb pdb:5D6J|rcsb pdb:5JNE|rcsb pdb:5KLX|rcsb pdb:5V8T|rcsb pdb:5YC2|rcsb pdb:5YCA|rcsb pdb:6CFP|rcsb pdb:6P81|rcsb pdb:6Q2S|rcsb pdb:6RPQ|rcsb pdb:6UKM|rcsb pdb:6UKU|rcsb pdb:6UKV|rcsb pdb:6UKW|rcsb pdb:6UKX|rcsb pdb:6UKY|rcsb pdb:6UKZ|rcsb pdb:6UL0|rcsb pdb:6VEL|rcsb pdb:6VW2|rcsb pdb:7LTO|reactome:R-SCE-3065676|reactome:R-SCE-3065678|reactome:R-SCE-3065679|reactome:R-SCE-3108214|reactome:R-SCE-3108232|reactome:R-SCE-3232118|reactome:R-SCE-3899300|reactome:R-SCE-4085377|reactome:R-SCE-4551638|reactome:R-SCE-4570464|reactome:R-SCE-4615885|reactome:R-SCE-9615933|dip:DIP-1364N|mint:Q12306	-	-	crc64:A2790DE7F315E1A7	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:o5XKyl1Z7AtQOJH5HBqkYh5w1n89606	rogid:oFdVBxN9WlDXTM7oAnv+1vfcXFQ559292	intact-crc:28BDC014445AEE28|rigid:i8fjIddAhSTcipIKW5M/FEzX96I	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P38340	uniprotkb:Q9HCK0	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-3918996|ensembl:ENSP00000362758|ensembl:ENSP00000362760|uniprotkb:B3KQ53|uniprotkb:Q8WTR1	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:zbt26_human(display_long)|uniprotkb:ZBTB26(gene name)|psi-mi:ZBTB26(display_short)|uniprotkb:KIAA1572(gene name synonym)|uniprotkb:ZNF481(gene name synonym)|uniprotkb:Zinc finger protein 481(gene name synonym)|uniprotkb:Zinc finger protein Bioref(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554332|imex:IM-24995-4154	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F	ensembl:ENSG00000171448(gene)|ensembl:ENST00000373654(transcript)|ensembl:ENST00000373656(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|refseq:NP_001291292.1|refseq:NP_001291293.1|refseq:NP_065975.1	-	crc64:66699F37B0013088	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:o5XKyl1Z7AtQOJH5HBqkYh5w1n89606	intact-crc:6DAA5D270F96676F|rigid:Ft7v8Okidfj2nRLaVFStbCWJREY	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q12259	uniprotkb:Q9HCK0	intact:EBI-30776|uniprotkb:D6VYA8|ensemblfungi:YLR108C	intact:EBI-3918996|ensembl:ENSP00000362758|ensembl:ENSP00000362760|uniprotkb:B3KQ53|uniprotkb:Q8WTR1	psi-mi:yl108_yeast(display_long)|uniprotkb:L2913(orf name)|uniprotkb:YLR108C(locus name)	psi-mi:zbt26_human(display_long)|uniprotkb:ZBTB26(gene name)|psi-mi:ZBTB26(display_short)|uniprotkb:KIAA1572(gene name synonym)|uniprotkb:ZNF481(gene name synonym)|uniprotkb:Zinc finger protein 481(gene name synonym)|uniprotkb:Zinc finger protein Bioref(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554328|imex:IM-24995-4153	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013209.1|sgd:S000004098|dip:DIP-4075N|ensemblfungi:YLR108C(gene)|ensemblfungi:YLR108C_mRNA(transcript)|go:"GO:0005634"(nucleus)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)	ensembl:ENSG00000171448(gene)|ensembl:ENST00000373654(transcript)|ensembl:ENST00000373656(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|refseq:NP_001291292.1|refseq:NP_001291293.1|refseq:NP_065975.1	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:CzknxXhhvgMp3J0/oi197EgZ05U559292	rogid:o5XKyl1Z7AtQOJH5HBqkYh5w1n89606	intact-crc:1FBAEB122FAA4E5F|rigid:5tlb+6Z+vOSQbEKkHD1npNvJT58	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9HCK0	uniprotkb:Q12161	intact:EBI-3918996|ensembl:ENSP00000362758|ensembl:ENSP00000362760|uniprotkb:B3KQ53|uniprotkb:Q8WTR1	intact:EBI-34372|uniprotkb:D6W213|ensemblfungi:YOL054W	psi-mi:zbt26_human(display_long)|uniprotkb:ZBTB26(gene name)|psi-mi:ZBTB26(display_short)|uniprotkb:KIAA1572(gene name synonym)|uniprotkb:ZNF481(gene name synonym)|uniprotkb:Zinc finger protein 481(gene name synonym)|uniprotkb:Zinc finger protein Bioref(gene name synonym)	psi-mi:psh1_yeast(display_long)|uniprotkb:PSH1(gene name)|psi-mi:PSH1(display_short)|uniprotkb:POB3/SPT16 histone-associated protein 1(gene name synonym)|uniprotkb:O1263(orf name)|uniprotkb:YOL054W(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554324|imex:IM-24995-4152	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000171448(gene)|ensembl:ENST00000373654(transcript)|ensembl:ENST00000373656(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|refseq:NP_001291292.1|refseq:NP_001291293.1|refseq:NP_065975.1	refseq:NP_014587.1|sgd:S000005415|mint:Q12161|dip:DIP-6481N|ensemblfungi:YOL054W(gene)|ensemblfungi:YOL054W_mRNA(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907	-	-	crc64:CE0ECBCB6D465554	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:o5XKyl1Z7AtQOJH5HBqkYh5w1n89606	rogid:AvPMRd/GjfaTyQjEfMPhBVcvOs4559292	intact-crc:E74B8664BADF82D2|rigid:jKLBoB6/t8N4vc0+0DqdOEqdbWY	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q02821	uniprotkb:Q9HAN9	intact:EBI-1797|uniprotkb:D6W0Z8|ensemblfungi:YNL189W	intact:EBI-3917542|uniprotkb:Q8TAE9|uniprotkb:Q9H6B6|uniprotkb:Q9H247|uniprotkb:B1AN63|ensembl:ENSP00000366410|ensembl:ENSP00000435134	psi-mi:ima1_yeast(display_long)|uniprotkb:SRP1(gene name)|psi-mi:SRP1(display_short)|uniprotkb:KAP60(gene name synonym)|uniprotkb:YNL189W(locus name)|uniprotkb:N1606(orf name)|uniprotkb:Karyopherin subunit alpha(gene name synonym)|uniprotkb:Karyopherin-60(gene name synonym)|uniprotkb:Serine-rich RNA polymerase I suppressor protein(gene name synonym)	psi-mi:nmna1_human(display_long)|uniprotkb:NMNAT1(gene name)|psi-mi:NMNAT1(display_short)|uniprotkb:NMNAT(gene name synonym)|uniprotkb:Nicotinate-nucleotide adenylyltransferase 1(gene name synonym)|uniprotkb:Nicotinamide-nucleotide adenylyltransferase 1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554320|imex:IM-24995-4151	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014210.1|sgd:S000005133|dip:DIP-728N|mint:Q02821|ensemblfungi:YNL189W(gene)|ensemblfungi:YNL189W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0031144"(proteasome localization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042564"(NLS-dependent protein nuclear import complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|rcsb pdb:1BK5|rcsb pdb:1BK6|rcsb pdb:1EE4|rcsb pdb:1EE5|rcsb pdb:1UN0|rcsb pdb:1WA5|rcsb pdb:2C1T|rcsb pdb:4PVZ|rcsb pdb:4XZR|rcsb pdb:5H2W|rcsb pdb:5H2X|rcsb pdb:5T94	refseq:NP_001284707.1|refseq:NP_073624.2|ensembl:ENSG00000173614(gene)|ensembl:ENST00000377205(transcript)|ensembl:ENST00000462686(transcript)|go:"GO:0000309"(nicotinamide-nucleotide adenylyltransferase activity)|go:"GO:0004515"(nicotinate-nucleotide adenylyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0009165"(nucleotide biosynthetic process)|go:"GO:0009435"(NAD biosynthetic process)|go:"GO:0009611"(response to wounding)|go:"GO:0016604"(nuclear body)|go:"GO:0042802"(identical protein binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:1902511"(negative regulation of apoptotic DNA fragmentation)|go:"GO:1990966"(ATP generation from poly-ADP-D-ribose)|interpro:IPR004821(Cytidyltransferase-related)|interpro:IPR005248(Probable nicotinate-nucleotide adenylyltransferase)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|mint:Q9HAN9|rcsb pdb:1GZU|rcsb pdb:1KKU|rcsb pdb:1KQN|rcsb pdb:1KQO|rcsb pdb:1KR2|reactome:R-HSA-196807|refseq:XP_016857596.1|dip:DIP-60881N	-	crc64:8D3A0CB76F2E7C00	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:NyzC93xnBCb8DX/AH346lwg4u2A559292	rogid:KwV9lz04z3ptlVpKu3b534Yekpc9606	intact-crc:2F1295E709008C19|rigid:hiVoR93U7NxzHo9Ck1njCpBKh28	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
intact:EBI-11522220	uniprotkb:Q9H9H4	-	intact:EBI-4400866|intact:EBI-28975719|ensembl:ENSP00000267202	psi-mi:lsb3(display_short)|psi-mi:EBI-11522220(display_long)	psi-mi:vp37b_human(display_long)|uniprotkb:VPS37B(gene name)|psi-mi:VPS37B(display_short)|uniprotkb:ESCRT-I complex subunit VPS37B(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554292|imex:IM-24995-4144	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSP00000267202|refseq:NP_078943.1|ensembl:ENSG00000139722(gene)|ensembl:ENST00000267202(transcript)|go:"GO:0000813"(ESCRT I complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0010008"(endosome membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0030496"(midbody)|go:"GO:0031902"(late endosome membrane)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1902188"(obsolete positive regulation of viral release from host cell)|go:"GO:1903774"(positive regulation of viral budding via host ESCRT complex)|interpro:IPR009851(Modifier of rudimentary, Modr)|interpro:IPR029012|interpro:IPR037202|mint:Q9H9H4|rcsb pdb:6VME|reactome:R-HSA-162588|reactome:R-HSA-174490|reactome:R-HSA-917729|reactome:R-HSA-9610379|reactome:R-HSA-9615710	-	no-uniprot-update:	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:lsGJZWImagMoiiCZztCcxCn2LlU4932	rogid:dj398+zsegXf+gk9OiSeZAVlmqk9606	intact-crc:54B3F4F7CD077888|rigid:UNiURDIqj4ktekX/LN3iVCNQy6o	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9HAN9	uniprotkb:Q06178	intact:EBI-3917542|uniprotkb:Q8TAE9|uniprotkb:Q9H6B6|uniprotkb:Q9H247|uniprotkb:B1AN63|ensembl:ENSP00000366410|ensembl:ENSP00000435134	intact:EBI-11803|ensemblfungi:YLR328W|uniprotkb:D6VYX0	psi-mi:nmna1_human(display_long)|uniprotkb:NMNAT1(gene name)|psi-mi:NMNAT1(display_short)|uniprotkb:NMNAT(gene name synonym)|uniprotkb:Nicotinate-nucleotide adenylyltransferase 1(gene name synonym)|uniprotkb:Nicotinamide-nucleotide adenylyltransferase 1(gene name synonym)	psi-mi:nma1_yeast(display_long)|uniprotkb:NMA1(gene name)|psi-mi:NMA1(display_short)|uniprotkb:"NAD(+) pyrophosphorylase 1"(gene name synonym)|uniprotkb:"NAD(+) diphosphorylase 1"(gene name synonym)|uniprotkb:Nicotinamide-nucleotide adenylyltransferase 1(gene name synonym)|uniprotkb:Nicotinate-nucleotide adenylyltransferase 1(gene name synonym)|uniprotkb:L8543.16(orf name)|uniprotkb:YLR328W(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554312|imex:IM-24995-4149	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001284707.1|refseq:NP_073624.2|ensembl:ENSG00000173614(gene)|ensembl:ENST00000377205(transcript)|ensembl:ENST00000462686(transcript)|go:"GO:0000309"(nicotinamide-nucleotide adenylyltransferase activity)|go:"GO:0004515"(nicotinate-nucleotide adenylyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0009165"(nucleotide biosynthetic process)|go:"GO:0009435"(NAD biosynthetic process)|go:"GO:0009611"(response to wounding)|go:"GO:0016604"(nuclear body)|go:"GO:0042802"(identical protein binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:1902511"(negative regulation of apoptotic DNA fragmentation)|go:"GO:1990966"(ATP generation from poly-ADP-D-ribose)|interpro:IPR004821(Cytidyltransferase-related)|interpro:IPR005248(Probable nicotinate-nucleotide adenylyltransferase)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|mint:Q9HAN9|rcsb pdb:1GZU|rcsb pdb:1KKU|rcsb pdb:1KQN|rcsb pdb:1KQO|rcsb pdb:1KR2|reactome:R-HSA-196807|refseq:XP_016857596.1|dip:DIP-60881N	ensemblfungi:YLR328W(gene)|ensemblfungi:YLR328W_mRNA(transcript)|go:"GO:0000309"(nicotinamide-nucleotide adenylyltransferase activity)|go:"GO:0004515"(nicotinate-nucleotide adenylyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009435"(NAD biosynthetic process)|go:"GO:0042802"(identical protein binding)|interpro:IPR004821(Cytidyltransferase-related)|interpro:IPR005248(Probable nicotinate-nucleotide adenylyltransferase)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|reactome:R-SCE-196807|refseq:NP_013432.1|sgd:S000004320|dip:DIP-1228N|mint:Q06178	-	-	crc64:A176964E56A30DD8	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:KwV9lz04z3ptlVpKu3b534Yekpc9606	rogid:VzrKsykGbQsR8Eh7CHCwn/bCID8559292	intact-crc:761AEC21B7DFA423|rigid:7dZJEHyGoAiPQXKWTkcPwt6rJi0	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P38340	uniprotkb:Q9HAN9	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-3917542|uniprotkb:Q8TAE9|uniprotkb:Q9H6B6|uniprotkb:Q9H247|uniprotkb:B1AN63|ensembl:ENSP00000366410|ensembl:ENSP00000435134	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:nmna1_human(display_long)|uniprotkb:NMNAT1(gene name)|psi-mi:NMNAT1(display_short)|uniprotkb:NMNAT(gene name synonym)|uniprotkb:Nicotinate-nucleotide adenylyltransferase 1(gene name synonym)|uniprotkb:Nicotinamide-nucleotide adenylyltransferase 1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554308|imex:IM-24995-4148	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F	refseq:NP_001284707.1|refseq:NP_073624.2|ensembl:ENSG00000173614(gene)|ensembl:ENST00000377205(transcript)|ensembl:ENST00000462686(transcript)|go:"GO:0000309"(nicotinamide-nucleotide adenylyltransferase activity)|go:"GO:0004515"(nicotinate-nucleotide adenylyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0009165"(nucleotide biosynthetic process)|go:"GO:0009435"(NAD biosynthetic process)|go:"GO:0009611"(response to wounding)|go:"GO:0016604"(nuclear body)|go:"GO:0042802"(identical protein binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:1902511"(negative regulation of apoptotic DNA fragmentation)|go:"GO:1990966"(ATP generation from poly-ADP-D-ribose)|interpro:IPR004821(Cytidyltransferase-related)|interpro:IPR005248(Probable nicotinate-nucleotide adenylyltransferase)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|mint:Q9HAN9|rcsb pdb:1GZU|rcsb pdb:1KKU|rcsb pdb:1KQN|rcsb pdb:1KQO|rcsb pdb:1KR2|reactome:R-HSA-196807|refseq:XP_016857596.1|dip:DIP-60881N	-	crc64:66699F37B0013088	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:KwV9lz04z3ptlVpKu3b534Yekpc9606	intact-crc:3929D5191F6D05DD|rigid:TsLbVS534F30ED4+TUYXBnjmJXc	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9H9H4	uniprotkb:P53829	intact:EBI-4400866|intact:EBI-28975719|ensembl:ENSP00000267202	intact:EBI-28306|uniprotkb:D6W0Q5|ensemblfungi:YNL288W	psi-mi:vp37b_human(display_long)|uniprotkb:VPS37B(gene name)|psi-mi:VPS37B(display_short)|uniprotkb:ESCRT-I complex subunit VPS37B(gene name synonym)	psi-mi:caf40_yeast(display_long)|uniprotkb:YNL288W(locus name)|uniprotkb:N0540(orf name)|uniprotkb:40 kDa CCR4-associated factor(gene name synonym)|uniprotkb:CAF40(gene name)|psi-mi:CAF40(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554304|imex:IM-24995-4147	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000267202|refseq:NP_078943.1|ensembl:ENSG00000139722(gene)|ensembl:ENST00000267202(transcript)|go:"GO:0000813"(ESCRT I complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0010008"(endosome membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0030496"(midbody)|go:"GO:0031902"(late endosome membrane)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1902188"(obsolete positive regulation of viral release from host cell)|go:"GO:1903774"(positive regulation of viral budding via host ESCRT complex)|interpro:IPR009851(Modifier of rudimentary, Modr)|interpro:IPR029012|interpro:IPR037202|mint:Q9H9H4|rcsb pdb:6VME|reactome:R-HSA-162588|reactome:R-HSA-174490|reactome:R-HSA-917729|reactome:R-HSA-9610379|reactome:R-HSA-9615710	refseq:NP_014111.1|sgd:S000005232|dip:DIP-1995N|mint:P53829|ensemblfungi:YNL288W(gene)|ensemblfungi:YNL288W_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR007216(Cell differentiation, Rcd1-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:4CV5	-	-	crc64:F3DBABE6AD3C7F3C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:dj398+zsegXf+gk9OiSeZAVlmqk9606	rogid:etuSSgFGQOcgxPDexEXUqQg6H5s559292	intact-crc:DDB4EFBF3D70FB01|rigid:l24RfhSGwCw99FUchlCxB27/nQY	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P25343	uniprotkb:Q9H9H4	intact:EBI-14490|uniprotkb:D6VR18|ensemblfungi:YCR009C	intact:EBI-4400866|intact:EBI-28975719|ensembl:ENSP00000267202	psi-mi:rv161_yeast(display_long)|uniprotkb:RVS161(gene name)|psi-mi:RVS161(display_short)|uniprotkb:END6(gene name synonym)|uniprotkb:SPE161(gene name synonym)|uniprotkb:YCR009C(locus name)|uniprotkb:YCR9C(orf name)	psi-mi:vp37b_human(display_long)|uniprotkb:VPS37B(gene name)|psi-mi:VPS37B(display_short)|uniprotkb:ESCRT-I complex subunit VPS37B(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554300|imex:IM-24995-4146	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YCR009C(gene)|ensemblfungi:YCR009C_mRNA(transcript)|go:"GO:0000747"(conjugation with cellular fusion)|go:"GO:0005829"(cytosol)|go:"GO:0005937"(mating projection)|go:"GO:0006897"(endocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030479"(actin cortical patch)|go:"GO:0031097"(medial cortex)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0042594"(response to starvation)|go:"GO:0043332"(mating projection tip)|go:"GO:0045121"(membrane raft)|go:"GO:0051666"(actin cortical patch localization)|go:"GO:0060988"(lipid tube assembly)|go:"GO:0097320"(plasma membrane tubulation)|go:"GO:1990528"(Rvs161p-Rvs167p complex)|interpro:IPR004148(BAR)|interpro:IPR027267|go:"GO:0006970"(response to osmotic stress)|interpro:IPR037429|refseq:NP_009935.1|sgd:S000000602|mint:P25343|dip:DIP-1601N	ensembl:ENSP00000267202|refseq:NP_078943.1|ensembl:ENSG00000139722(gene)|ensembl:ENST00000267202(transcript)|go:"GO:0000813"(ESCRT I complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0010008"(endosome membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0030496"(midbody)|go:"GO:0031902"(late endosome membrane)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1902188"(obsolete positive regulation of viral release from host cell)|go:"GO:1903774"(positive regulation of viral budding via host ESCRT complex)|interpro:IPR009851(Modifier of rudimentary, Modr)|interpro:IPR029012|interpro:IPR037202|mint:Q9H9H4|rcsb pdb:6VME|reactome:R-HSA-162588|reactome:R-HSA-174490|reactome:R-HSA-917729|reactome:R-HSA-9610379|reactome:R-HSA-9615710	-	crc64:B35EA00E0C900E2D	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:IdjO8RS5vcYMeGxuoPoa/5e7QJQ559292	rogid:dj398+zsegXf+gk9OiSeZAVlmqk9606	intact-crc:A750A036527B8063|rigid:pgwHh6rLZ+gz+I8+RrqpD7S9KyI	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9H9H4	uniprotkb:P39961	intact:EBI-4400866|intact:EBI-28975719|ensembl:ENSP00000267202	intact:EBI-22239|uniprotkb:D3DM93|ensemblfungi:YER184C	psi-mi:vp37b_human(display_long)|uniprotkb:VPS37B(gene name)|psi-mi:VPS37B(display_short)|uniprotkb:ESCRT-I complex subunit VPS37B(gene name synonym)	psi-mi:tog1_yeast(display_long)|uniprotkb:TOG1(gene name)|psi-mi:TOG1(display_short)|uniprotkb:Transcriptional regulator of oleate 1(gene name synonym)|uniprotkb:YER184C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554296|imex:IM-24995-4145	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000267202|refseq:NP_078943.1|ensembl:ENSG00000139722(gene)|ensembl:ENST00000267202(transcript)|go:"GO:0000813"(ESCRT I complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0010008"(endosome membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0030496"(midbody)|go:"GO:0031902"(late endosome membrane)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1902188"(obsolete positive regulation of viral release from host cell)|go:"GO:1903774"(positive regulation of viral budding via host ESCRT complex)|interpro:IPR009851(Modifier of rudimentary, Modr)|interpro:IPR029012|interpro:IPR037202|mint:Q9H9H4|rcsb pdb:6VME|reactome:R-HSA-162588|reactome:R-HSA-174490|reactome:R-HSA-917729|reactome:R-HSA-9610379|reactome:R-HSA-9615710	refseq:NP_011111.1|sgd:S000000986|dip:DIP-5488N|mint:P39961|ensemblfungi:YER184C(gene)|ensemblfungi:YER184C_mRNA(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR001138(Fungal transcriptional regulatory protein, N-terminal)|interpro:IPR007219(Fungal specific transcription factor)|interpro:IPR036864	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:dj398+zsegXf+gk9OiSeZAVlmqk9606	rogid:5LvJUSL4Do4rBxPon6hQplqYXFU559292	intact-crc:812F4C19C1069711|rigid:T3u93KxnR1U6au4MV/V3opPIwjE	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9HAN9	uniprotkb:P38151	intact:EBI-3917542|uniprotkb:Q8TAE9|uniprotkb:Q9H6B6|uniprotkb:Q9H247|uniprotkb:B1AN63|ensembl:ENSP00000366410|ensembl:ENSP00000435134	intact:EBI-12968|uniprotkb:D6VQM8|ensemblfungi:YBR233W	psi-mi:nmna1_human(display_long)|uniprotkb:NMNAT1(gene name)|psi-mi:NMNAT1(display_short)|uniprotkb:NMNAT(gene name synonym)|uniprotkb:Nicotinate-nucleotide adenylyltransferase 1(gene name synonym)|uniprotkb:Nicotinamide-nucleotide adenylyltransferase 1(gene name synonym)	psi-mi:pbp2_yeast(display_long)|uniprotkb:YBR1531(orf name)|uniprotkb:YBR233W(locus name)|uniprotkb:PBP2(gene name)|psi-mi:PBP2(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554316|imex:IM-24995-4150	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001284707.1|refseq:NP_073624.2|ensembl:ENSG00000173614(gene)|ensembl:ENST00000377205(transcript)|ensembl:ENST00000462686(transcript)|go:"GO:0000309"(nicotinamide-nucleotide adenylyltransferase activity)|go:"GO:0004515"(nicotinate-nucleotide adenylyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0009165"(nucleotide biosynthetic process)|go:"GO:0009435"(NAD biosynthetic process)|go:"GO:0009611"(response to wounding)|go:"GO:0016604"(nuclear body)|go:"GO:0042802"(identical protein binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:1902511"(negative regulation of apoptotic DNA fragmentation)|go:"GO:1990966"(ATP generation from poly-ADP-D-ribose)|interpro:IPR004821(Cytidyltransferase-related)|interpro:IPR005248(Probable nicotinate-nucleotide adenylyltransferase)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|mint:Q9HAN9|rcsb pdb:1GZU|rcsb pdb:1KKU|rcsb pdb:1KQN|rcsb pdb:1KQO|rcsb pdb:1KR2|reactome:R-HSA-196807|refseq:XP_016857596.1|dip:DIP-60881N	sgd:S000000437|refseq:NP_009792.3|dip:DIP-4947N|ensemblfungi:YBR233W(gene)|ensemblfungi:YBR233W_mRNA(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0051252"(regulation of RNA metabolic process)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR036612	-	-	crc64:638846509BCE1840	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:KwV9lz04z3ptlVpKu3b534Yekpc9606	rogid:zcN9K+pivnit4l3Cl75wfk5F4VI559292	intact-crc:E0B4CE68BEE5F9AB|rigid:ueKN62aID4CjKR81IgQzdYM3Tk8	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9HCM9-2	uniprotkb:P52917	intact:EBI-11523450|ensembl:ENSP00000365847|ensembl:ENSP00000373095|ensembl:ENSP00000373097|ensembl:ENSP00000379797|ensembl:ENSP00000379800|ensembl:ENSP00000383486|ensembl:ENSP00000387445|ensembl:ENSP00000389198|ensembl:ENSP00000389852|ensembl:ENSP00000392130|ensembl:ENSP00000394353|ensembl:ENSP00000396986|ensembl:ENSP00000398956|ensembl:ENSP00000401071|ensembl:ENSP00000401184|ensembl:ENSP00000404340|ensembl:ENSP00000404904|ensembl:ENSP00000411582|ensembl:ENSP00000412743|ensembl:ENSP00000414525|ensembl:ENSP00000415259	intact:EBI-20475|uniprotkb:D6W4H4|ensemblfungi:YPR173C	psi-mi:q9hcm9-2(display_long)|uniprotkb:TRIM39(gene name)|psi-mi:TRIM39(display_short)|uniprotkb:RING finger protein 23(gene name synonym)|uniprotkb:RNF23(gene name synonym)|uniprotkb:TFP(gene name synonym)|uniprotkb:Testis-abundant finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 39(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM39(gene name synonym)|uniprotkb:TIM39beta(isoform synonym)	psi-mi:vps4_yeast(display_long)|uniprotkb:VPS4(gene name)|psi-mi:VPS4(display_short)|uniprotkb:CSC1(gene name synonym)|uniprotkb:END13(gene name synonym)|uniprotkb:GRD13(gene name synonym)|uniprotkb:DID6(gene name synonym)|uniprotkb:Protein END13(gene name synonym)|uniprotkb:DOA4-independent degradation protein 6(gene name synonym)|uniprotkb:Vacuolar protein-targeting protein 10(gene name synonym)|uniprotkb:VPL4(gene name synonym)|uniprotkb:VPT10(gene name synonym)|uniprotkb:P9705.10(orf name)|uniprotkb:YPR173C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554368|imex:IM-24995-4163	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-739510(isoform-parent)|ensembl:ENSG00000204599(gene)|ensembl:ENSG00000206495(gene)|ensembl:ENSG00000224994(gene)|ensembl:ENSG00000226437(gene)|ensembl:ENSG00000229929(gene)|ensembl:ENSG00000230308(gene)|ensembl:ENSG00000232839(gene)|ensembl:ENST00000376659(transcript)|ensembl:ENST00000383601(transcript)|ensembl:ENST00000383603(transcript)|ensembl:ENST00000396548(transcript)|ensembl:ENST00000396551(transcript)|ensembl:ENST00000400644(transcript)|ensembl:ENST00000414015(transcript)|ensembl:ENST00000419790(transcript)|ensembl:ENST00000430502(transcript)|ensembl:ENST00000431272(transcript)|ensembl:ENST00000433900(transcript)|ensembl:ENST00000438076(transcript)|ensembl:ENST00000438859(transcript)|ensembl:ENST00000440117(transcript)|ensembl:ENST00000443109(transcript)|ensembl:ENST00000446397(transcript)|ensembl:ENST00000449318(transcript)|ensembl:ENST00000450778(transcript)|ensembl:ENST00000451132(transcript)|ensembl:ENST00000452705(transcript)|ensembl:ENST00000458607(transcript)|uniprotkb:Q9HCM9-2(isoform-parent)	refseq:NP_015499.1|sgd:S000006377|ensemblfungi:YPR173C(gene)|ensemblfungi:YPR173C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0007033"(vacuole organization)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0016197"(endosomal transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045053"(protein retention in Golgi apparatus)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0061709"(reticulophagy)|go:"GO:0070676"(intralumenal vesicle formation)|go:"GO:1990621"(ESCRT IV complex)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR007330(MIT)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR027417|interpro:IPR036181|rcsb pdb:2QP9|rcsb pdb:2QPA|rcsb pdb:2RKO|rcsb pdb:2V6X|rcsb pdb:3EIE|rcsb pdb:3EIH|rcsb pdb:3MHV|rcsb pdb:4NIQ|rcsb pdb:5FVK|rcsb pdb:5FVL|rcsb pdb:5UIE|rcsb pdb:5XMI|rcsb pdb:5XMK|rcsb pdb:6AP1|rcsb pdb:6BMF|rcsb pdb:6NDY|rcsb pdb:6OO2|reactome:R-SCE-917729|reactome:R-SCE-9668328|dip:DIP-1746N|mint:P52917	-	-	crc64:E65BCDB19C9510DD	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:UfSn2+IVRxtGomVeDGdZpL7mz5I9606	rogid:qXGTfZcBZ9jWOVjm6tl3wIR/ngM559292	intact-crc:3B4315F59289ABF2|rigid:QNirPDE+f0Ap2Ljj1NcZWn7j2PE	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9HCM9-2	uniprotkb:P47107	intact:EBI-11523450|ensembl:ENSP00000365847|ensembl:ENSP00000373095|ensembl:ENSP00000373097|ensembl:ENSP00000379797|ensembl:ENSP00000379800|ensembl:ENSP00000383486|ensembl:ENSP00000387445|ensembl:ENSP00000389198|ensembl:ENSP00000389852|ensembl:ENSP00000392130|ensembl:ENSP00000394353|ensembl:ENSP00000396986|ensembl:ENSP00000398956|ensembl:ENSP00000401071|ensembl:ENSP00000401184|ensembl:ENSP00000404340|ensembl:ENSP00000404904|ensembl:ENSP00000411582|ensembl:ENSP00000412743|ensembl:ENSP00000414525|ensembl:ENSP00000415259	intact:EBI-2344909|uniprotkb:D6VWL0|ensemblfungi:YJR039W	psi-mi:q9hcm9-2(display_long)|uniprotkb:TRIM39(gene name)|psi-mi:TRIM39(display_short)|uniprotkb:RING finger protein 23(gene name synonym)|uniprotkb:RNF23(gene name synonym)|uniprotkb:TFP(gene name synonym)|uniprotkb:Testis-abundant finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 39(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM39(gene name synonym)|uniprotkb:TIM39beta(isoform synonym)	psi-mi:yj09_yeast(display_long)|uniprotkb:J1614(orf name)|uniprotkb:YJR039W(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554364|imex:IM-24995-4162	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-739510(isoform-parent)|ensembl:ENSG00000204599(gene)|ensembl:ENSG00000206495(gene)|ensembl:ENSG00000224994(gene)|ensembl:ENSG00000226437(gene)|ensembl:ENSG00000229929(gene)|ensembl:ENSG00000230308(gene)|ensembl:ENSG00000232839(gene)|ensembl:ENST00000376659(transcript)|ensembl:ENST00000383601(transcript)|ensembl:ENST00000383603(transcript)|ensembl:ENST00000396548(transcript)|ensembl:ENST00000396551(transcript)|ensembl:ENST00000400644(transcript)|ensembl:ENST00000414015(transcript)|ensembl:ENST00000419790(transcript)|ensembl:ENST00000430502(transcript)|ensembl:ENST00000431272(transcript)|ensembl:ENST00000433900(transcript)|ensembl:ENST00000438076(transcript)|ensembl:ENST00000438859(transcript)|ensembl:ENST00000440117(transcript)|ensembl:ENST00000443109(transcript)|ensembl:ENST00000446397(transcript)|ensembl:ENST00000449318(transcript)|ensembl:ENST00000450778(transcript)|ensembl:ENST00000451132(transcript)|ensembl:ENST00000452705(transcript)|ensembl:ENST00000458607(transcript)|uniprotkb:Q9HCM9-2(isoform-parent)	sgd:S000003800|refseq:NP_012573.1|ensemblfungi:YJR039W(gene)|ensemblfungi:YJR039W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:UfSn2+IVRxtGomVeDGdZpL7mz5I9606	rogid:79jOtKfgrrdJYmThBSRaCtpPF5A559292	intact-crc:A4E9C2A153FE634D|rigid:0feV6Q6LdnFm13FzOqFPEOK8Dyg	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P21734	uniprotkb:Q9HCM9-2	intact:EBI-19717|uniprotkb:D6VSF9|ensemblfungi:YDR177W	intact:EBI-11523450|ensembl:ENSP00000365847|ensembl:ENSP00000373095|ensembl:ENSP00000373097|ensembl:ENSP00000379797|ensembl:ENSP00000379800|ensembl:ENSP00000383486|ensembl:ENSP00000387445|ensembl:ENSP00000389198|ensembl:ENSP00000389852|ensembl:ENSP00000392130|ensembl:ENSP00000394353|ensembl:ENSP00000396986|ensembl:ENSP00000398956|ensembl:ENSP00000401071|ensembl:ENSP00000401184|ensembl:ENSP00000404340|ensembl:ENSP00000404904|ensembl:ENSP00000411582|ensembl:ENSP00000412743|ensembl:ENSP00000414525|ensembl:ENSP00000415259	psi-mi:ubc1_yeast(display_long)|uniprotkb:UBC1(gene name)|psi-mi:UBC1(display_short)|uniprotkb:YDR177W(locus name)|uniprotkb:YD9395.10(orf name)|uniprotkb:Ubiquitin-protein ligase(gene name synonym)|uniprotkb:Ubiquitin carrier protein(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-24 kDa(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme 1(gene name synonym)	psi-mi:q9hcm9-2(display_long)|uniprotkb:TRIM39(gene name)|psi-mi:TRIM39(display_short)|uniprotkb:RING finger protein 23(gene name synonym)|uniprotkb:RNF23(gene name synonym)|uniprotkb:TFP(gene name synonym)|uniprotkb:Testis-abundant finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 39(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM39(gene name synonym)|uniprotkb:TIM39beta(isoform synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554360|imex:IM-24995-4161	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002584|ensemblfungi:YDR177W(gene)|ensemblfungi:YDR177W_mRNA(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016050"(vesicle organization)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070628"(proteasome binding)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR009060(UBA-like)|interpro:IPR015368(Ubiquitin-conjugating enzyme, C-terminal fungi)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1FXT|rcsb pdb:1FZY|rcsb pdb:1TTE|reactome:R-SCE-8866652|reactome:R-SCE-983168|refseq:NP_010462.3|dip:DIP-6594N|mint:P21734	intact:EBI-739510(isoform-parent)|ensembl:ENSG00000204599(gene)|ensembl:ENSG00000206495(gene)|ensembl:ENSG00000224994(gene)|ensembl:ENSG00000226437(gene)|ensembl:ENSG00000229929(gene)|ensembl:ENSG00000230308(gene)|ensembl:ENSG00000232839(gene)|ensembl:ENST00000376659(transcript)|ensembl:ENST00000383601(transcript)|ensembl:ENST00000383603(transcript)|ensembl:ENST00000396548(transcript)|ensembl:ENST00000396551(transcript)|ensembl:ENST00000400644(transcript)|ensembl:ENST00000414015(transcript)|ensembl:ENST00000419790(transcript)|ensembl:ENST00000430502(transcript)|ensembl:ENST00000431272(transcript)|ensembl:ENST00000433900(transcript)|ensembl:ENST00000438076(transcript)|ensembl:ENST00000438859(transcript)|ensembl:ENST00000440117(transcript)|ensembl:ENST00000443109(transcript)|ensembl:ENST00000446397(transcript)|ensembl:ENST00000449318(transcript)|ensembl:ENST00000450778(transcript)|ensembl:ENST00000451132(transcript)|ensembl:ENST00000452705(transcript)|ensembl:ENST00000458607(transcript)|uniprotkb:Q9HCM9-2(isoform-parent)	-	crc64:899CC397A1285145	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:3N1WHZJcgMeK0OglGpGI2m4XU8Q559292	rogid:UfSn2+IVRxtGomVeDGdZpL7mz5I9606	intact-crc:0AD1BF6926AA2C79|rigid:diOzZx6LRU1fphQaRrHjmYvYAd0	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P26343	uniprotkb:Q9HCM9-2	intact:EBI-5489|uniprotkb:D6VX97|ensemblfungi:YKR034W	intact:EBI-11523450|ensembl:ENSP00000365847|ensembl:ENSP00000373095|ensembl:ENSP00000373097|ensembl:ENSP00000379797|ensembl:ENSP00000379800|ensembl:ENSP00000383486|ensembl:ENSP00000387445|ensembl:ENSP00000389198|ensembl:ENSP00000389852|ensembl:ENSP00000392130|ensembl:ENSP00000394353|ensembl:ENSP00000396986|ensembl:ENSP00000398956|ensembl:ENSP00000401071|ensembl:ENSP00000401184|ensembl:ENSP00000404340|ensembl:ENSP00000404904|ensembl:ENSP00000411582|ensembl:ENSP00000412743|ensembl:ENSP00000414525|ensembl:ENSP00000415259	psi-mi:dal80_yeast(display_long)|uniprotkb:YKR034W(locus name)|uniprotkb:DAL80(gene name)|psi-mi:DAL80(display_short)|uniprotkb:UGA43(gene name synonym)|uniprotkb:Regulatory protein UGA43(gene name synonym)	psi-mi:q9hcm9-2(display_long)|uniprotkb:TRIM39(gene name)|psi-mi:TRIM39(display_short)|uniprotkb:RING finger protein 23(gene name synonym)|uniprotkb:RNF23(gene name synonym)|uniprotkb:TFP(gene name synonym)|uniprotkb:Testis-abundant finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 39(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM39(gene name synonym)|uniprotkb:TIM39beta(isoform synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554340|imex:IM-24995-4156	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012959.1|sgd:S000001742|dip:DIP-2094N|ensemblfungi:YKR034W(gene)|ensemblfungi:YKR034W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042128"(nitrate assimilation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0090295"(nitrogen catabolite repression of transcription)|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR039355	intact:EBI-739510(isoform-parent)|ensembl:ENSG00000204599(gene)|ensembl:ENSG00000206495(gene)|ensembl:ENSG00000224994(gene)|ensembl:ENSG00000226437(gene)|ensembl:ENSG00000229929(gene)|ensembl:ENSG00000230308(gene)|ensembl:ENSG00000232839(gene)|ensembl:ENST00000376659(transcript)|ensembl:ENST00000383601(transcript)|ensembl:ENST00000383603(transcript)|ensembl:ENST00000396548(transcript)|ensembl:ENST00000396551(transcript)|ensembl:ENST00000400644(transcript)|ensembl:ENST00000414015(transcript)|ensembl:ENST00000419790(transcript)|ensembl:ENST00000430502(transcript)|ensembl:ENST00000431272(transcript)|ensembl:ENST00000433900(transcript)|ensembl:ENST00000438076(transcript)|ensembl:ENST00000438859(transcript)|ensembl:ENST00000440117(transcript)|ensembl:ENST00000443109(transcript)|ensembl:ENST00000446397(transcript)|ensembl:ENST00000449318(transcript)|ensembl:ENST00000450778(transcript)|ensembl:ENST00000451132(transcript)|ensembl:ENST00000452705(transcript)|ensembl:ENST00000458607(transcript)|uniprotkb:Q9HCM9-2(isoform-parent)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Qfoc7DZ+/Nwthc4Hf93+iwuYgVg559292	rogid:UfSn2+IVRxtGomVeDGdZpL7mz5I9606	intact-crc:A3125D098AB10662|rigid:yi5zVgyt3q9xUyRgtYtQ4W4qgXI	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P37263	uniprotkb:Q9HCM9-2	intact:EBI-21659|uniprotkb:D6VR87|ensemblfungi:YCR087C-A	intact:EBI-11523450|ensembl:ENSP00000365847|ensembl:ENSP00000373095|ensembl:ENSP00000373097|ensembl:ENSP00000379797|ensembl:ENSP00000379800|ensembl:ENSP00000383486|ensembl:ENSP00000387445|ensembl:ENSP00000389198|ensembl:ENSP00000389852|ensembl:ENSP00000392130|ensembl:ENSP00000394353|ensembl:ENSP00000396986|ensembl:ENSP00000398956|ensembl:ENSP00000401071|ensembl:ENSP00000401184|ensembl:ENSP00000404340|ensembl:ENSP00000404904|ensembl:ENSP00000411582|ensembl:ENSP00000412743|ensembl:ENSP00000414525|ensembl:ENSP00000415259	psi-mi:yc16_yeast(display_long)|uniprotkb:YCRX16C(orf name)|uniprotkb:YCR087C-A(locus name)	psi-mi:q9hcm9-2(display_long)|uniprotkb:TRIM39(gene name)|psi-mi:TRIM39(display_short)|uniprotkb:RING finger protein 23(gene name synonym)|uniprotkb:RNF23(gene name synonym)|uniprotkb:TFP(gene name synonym)|uniprotkb:Testis-abundant finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 39(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM39(gene name synonym)|uniprotkb:TIM39beta(isoform synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554352|imex:IM-24995-4159	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010011.1|sgd:S000007223|mint:P37263|dip:DIP-4536N|ensemblfungi:YCR087C-A(gene)|ensemblfungi:YCR087C-A_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR014898(Zinc finger, C2H2, LYAR-type)|interpro:IPR036236|interpro:IPR039999	intact:EBI-739510(isoform-parent)|ensembl:ENSG00000204599(gene)|ensembl:ENSG00000206495(gene)|ensembl:ENSG00000224994(gene)|ensembl:ENSG00000226437(gene)|ensembl:ENSG00000229929(gene)|ensembl:ENSG00000230308(gene)|ensembl:ENSG00000232839(gene)|ensembl:ENST00000376659(transcript)|ensembl:ENST00000383601(transcript)|ensembl:ENST00000383603(transcript)|ensembl:ENST00000396548(transcript)|ensembl:ENST00000396551(transcript)|ensembl:ENST00000400644(transcript)|ensembl:ENST00000414015(transcript)|ensembl:ENST00000419790(transcript)|ensembl:ENST00000430502(transcript)|ensembl:ENST00000431272(transcript)|ensembl:ENST00000433900(transcript)|ensembl:ENST00000438076(transcript)|ensembl:ENST00000438859(transcript)|ensembl:ENST00000440117(transcript)|ensembl:ENST00000443109(transcript)|ensembl:ENST00000446397(transcript)|ensembl:ENST00000449318(transcript)|ensembl:ENST00000450778(transcript)|ensembl:ENST00000451132(transcript)|ensembl:ENST00000452705(transcript)|ensembl:ENST00000458607(transcript)|uniprotkb:Q9HCM9-2(isoform-parent)	-	crc64:B5B3B4CA37B82042	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:I7iIzRqPZAKdWQSe/IeGsW0qQcU559292	rogid:UfSn2+IVRxtGomVeDGdZpL7mz5I9606	intact-crc:B1F27E683A693C1C|rigid:s7Y0G+75Dh7YfGv3z3b4iFW+XHA	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9HCM9-2	uniprotkb:P38879	intact:EBI-11523450|ensembl:ENSP00000365847|ensembl:ENSP00000373095|ensembl:ENSP00000373097|ensembl:ENSP00000379797|ensembl:ENSP00000379800|ensembl:ENSP00000383486|ensembl:ENSP00000387445|ensembl:ENSP00000389198|ensembl:ENSP00000389852|ensembl:ENSP00000392130|ensembl:ENSP00000394353|ensembl:ENSP00000396986|ensembl:ENSP00000398956|ensembl:ENSP00000401071|ensembl:ENSP00000401184|ensembl:ENSP00000404340|ensembl:ENSP00000404904|ensembl:ENSP00000411582|ensembl:ENSP00000412743|ensembl:ENSP00000414525|ensembl:ENSP00000415259	intact:EBI-6379|uniprotkb:D3DLE1|ensemblfungi:YHR193C	psi-mi:q9hcm9-2(display_long)|uniprotkb:TRIM39(gene name)|psi-mi:TRIM39(display_short)|uniprotkb:RING finger protein 23(gene name synonym)|uniprotkb:RNF23(gene name synonym)|uniprotkb:TFP(gene name synonym)|uniprotkb:Testis-abundant finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 39(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM39(gene name synonym)|uniprotkb:TIM39beta(isoform synonym)	psi-mi:naca_yeast(display_long)|uniprotkb:EGD2(gene name)|psi-mi:EGD2(display_short)|uniprotkb:Alpha-NAC(gene name synonym)|uniprotkb:GAL4 DNA-binding enhancer protein 2(gene name synonym)|uniprotkb:YHR193C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554348|imex:IM-24995-4158	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-739510(isoform-parent)|ensembl:ENSG00000204599(gene)|ensembl:ENSG00000206495(gene)|ensembl:ENSG00000224994(gene)|ensembl:ENSG00000226437(gene)|ensembl:ENSG00000229929(gene)|ensembl:ENSG00000230308(gene)|ensembl:ENSG00000232839(gene)|ensembl:ENST00000376659(transcript)|ensembl:ENST00000383601(transcript)|ensembl:ENST00000383603(transcript)|ensembl:ENST00000396548(transcript)|ensembl:ENST00000396551(transcript)|ensembl:ENST00000400644(transcript)|ensembl:ENST00000414015(transcript)|ensembl:ENST00000419790(transcript)|ensembl:ENST00000430502(transcript)|ensembl:ENST00000431272(transcript)|ensembl:ENST00000433900(transcript)|ensembl:ENST00000438076(transcript)|ensembl:ENST00000438859(transcript)|ensembl:ENST00000440117(transcript)|ensembl:ENST00000443109(transcript)|ensembl:ENST00000446397(transcript)|ensembl:ENST00000449318(transcript)|ensembl:ENST00000450778(transcript)|ensembl:ENST00000451132(transcript)|ensembl:ENST00000452705(transcript)|ensembl:ENST00000458607(transcript)|uniprotkb:Q9HCM9-2(isoform-parent)	sgd:S000001236|refseq:NP_012063.3|mint:P38879|dip:DIP-2098N|ensemblfungi:YHR193C(gene)|ensemblfungi:YHR193C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005854"(nascent polypeptide-associated complex)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0070300"(phosphatidic acid binding)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|interpro:IPR002715(Nascent polypeptide-associated complex NAC)|interpro:IPR009060(UBA-like)|interpro:IPR016641(Nascent polypeptide-associated complex, alpha subunit)|interpro:IPR038187|interpro:IPR044034	-	-	crc64:86CE0C4E6194C286	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:UfSn2+IVRxtGomVeDGdZpL7mz5I9606	rogid:IjsgR+hZDgTQDvy2Wf8JEX4kF+A559292	intact-crc:DCD4D199BC8DE544|rigid:A0MHhunKyob6sVK1SSl8etIg/pU	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9HCM9-2	uniprotkb:Q02209	intact:EBI-11523450|ensembl:ENSP00000365847|ensembl:ENSP00000373095|ensembl:ENSP00000373097|ensembl:ENSP00000379797|ensembl:ENSP00000379800|ensembl:ENSP00000383486|ensembl:ENSP00000387445|ensembl:ENSP00000389198|ensembl:ENSP00000389852|ensembl:ENSP00000392130|ensembl:ENSP00000394353|ensembl:ENSP00000396986|ensembl:ENSP00000398956|ensembl:ENSP00000401071|ensembl:ENSP00000401184|ensembl:ENSP00000404340|ensembl:ENSP00000404904|ensembl:ENSP00000411582|ensembl:ENSP00000412743|ensembl:ENSP00000414525|ensembl:ENSP00000415259	intact:EBI-27066|uniprotkb:D6VX77|ensemblfungi:YKR011C	psi-mi:q9hcm9-2(display_long)|uniprotkb:TRIM39(gene name)|psi-mi:TRIM39(display_short)|uniprotkb:RING finger protein 23(gene name synonym)|uniprotkb:RNF23(gene name synonym)|uniprotkb:TFP(gene name synonym)|uniprotkb:Testis-abundant finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 39(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM39(gene name synonym)|uniprotkb:TIM39beta(isoform synonym)	psi-mi:ykz1_yeast(display_long)|uniprotkb:YK110(orf name)|uniprotkb:YKR011C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554344|imex:IM-24995-4157	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-739510(isoform-parent)|ensembl:ENSG00000204599(gene)|ensembl:ENSG00000206495(gene)|ensembl:ENSG00000224994(gene)|ensembl:ENSG00000226437(gene)|ensembl:ENSG00000229929(gene)|ensembl:ENSG00000230308(gene)|ensembl:ENSG00000232839(gene)|ensembl:ENST00000376659(transcript)|ensembl:ENST00000383601(transcript)|ensembl:ENST00000383603(transcript)|ensembl:ENST00000396548(transcript)|ensembl:ENST00000396551(transcript)|ensembl:ENST00000400644(transcript)|ensembl:ENST00000414015(transcript)|ensembl:ENST00000419790(transcript)|ensembl:ENST00000430502(transcript)|ensembl:ENST00000431272(transcript)|ensembl:ENST00000433900(transcript)|ensembl:ENST00000438076(transcript)|ensembl:ENST00000438859(transcript)|ensembl:ENST00000440117(transcript)|ensembl:ENST00000443109(transcript)|ensembl:ENST00000446397(transcript)|ensembl:ENST00000449318(transcript)|ensembl:ENST00000450778(transcript)|ensembl:ENST00000451132(transcript)|ensembl:ENST00000452705(transcript)|ensembl:ENST00000458607(transcript)|uniprotkb:Q9HCM9-2(isoform-parent)	sgd:S000001719|refseq:NP_012936.1|mint:Q02209|dip:DIP-1923N|ensemblfungi:YKR011C(gene)|ensemblfungi:YKR011C_mRNA(transcript)|go:"GO:0005634"(nucleus)	-	-	crc64:785423803C0EAD6A	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:UfSn2+IVRxtGomVeDGdZpL7mz5I9606	rogid:DWbgg9PhX711mFipd/pvqT970D4559292	intact-crc:67C910166DE7D3F6|rigid:4pCUiK7bgdX8xPoHVTffVv/B03Q	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9HCM9-2	uniprotkb:Q07379	intact:EBI-11523450|ensembl:ENSP00000365847|ensembl:ENSP00000373095|ensembl:ENSP00000373097|ensembl:ENSP00000379797|ensembl:ENSP00000379800|ensembl:ENSP00000383486|ensembl:ENSP00000387445|ensembl:ENSP00000389198|ensembl:ENSP00000389852|ensembl:ENSP00000392130|ensembl:ENSP00000394353|ensembl:ENSP00000396986|ensembl:ENSP00000398956|ensembl:ENSP00000401071|ensembl:ENSP00000401184|ensembl:ENSP00000404340|ensembl:ENSP00000404904|ensembl:ENSP00000411582|ensembl:ENSP00000412743|ensembl:ENSP00000414525|ensembl:ENSP00000415259	intact:EBI-2342994|uniprotkb:D6VRT9|ensemblfungi:YDL057W	psi-mi:q9hcm9-2(display_long)|uniprotkb:TRIM39(gene name)|psi-mi:TRIM39(display_short)|uniprotkb:RING finger protein 23(gene name synonym)|uniprotkb:RNF23(gene name synonym)|uniprotkb:TFP(gene name synonym)|uniprotkb:Testis-abundant finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 39(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM39(gene name synonym)|uniprotkb:TIM39beta(isoform synonym)	psi-mi:yd057_yeast(display_long)|uniprotkb:YDL057W(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554356|imex:IM-24995-4160	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-739510(isoform-parent)|ensembl:ENSG00000204599(gene)|ensembl:ENSG00000206495(gene)|ensembl:ENSG00000224994(gene)|ensembl:ENSG00000226437(gene)|ensembl:ENSG00000229929(gene)|ensembl:ENSG00000230308(gene)|ensembl:ENSG00000232839(gene)|ensembl:ENST00000376659(transcript)|ensembl:ENST00000383601(transcript)|ensembl:ENST00000383603(transcript)|ensembl:ENST00000396548(transcript)|ensembl:ENST00000396551(transcript)|ensembl:ENST00000400644(transcript)|ensembl:ENST00000414015(transcript)|ensembl:ENST00000419790(transcript)|ensembl:ENST00000430502(transcript)|ensembl:ENST00000431272(transcript)|ensembl:ENST00000433900(transcript)|ensembl:ENST00000438076(transcript)|ensembl:ENST00000438859(transcript)|ensembl:ENST00000440117(transcript)|ensembl:ENST00000443109(transcript)|ensembl:ENST00000446397(transcript)|ensembl:ENST00000449318(transcript)|ensembl:ENST00000450778(transcript)|ensembl:ENST00000451132(transcript)|ensembl:ENST00000452705(transcript)|ensembl:ENST00000458607(transcript)|uniprotkb:Q9HCM9-2(isoform-parent)	sgd:S000002215|refseq:NP_010226.1|interpro:IPR022742|interpro:IPR029058|ensemblfungi:YDL057W(gene)|ensemblfungi:YDL057W_mRNA(transcript)|go:"GO:0016020"(membrane)|go:"GO:0016298"(lipase activity)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:UfSn2+IVRxtGomVeDGdZpL7mz5I9606	rogid:U0Sf+t16Ti+vYEOEePrGjlqflhQ559292	intact-crc:D76B2977D8CC2871|rigid:LujSrb70dn9603zLaNySPeB9lTQ	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9HD26-2	uniprotkb:P21651	intact:EBI-11102276|ensembl:ENSP00000052569	intact:EBI-10742|ensemblfungi:YJR021C|uniprotkb:D6VWJ5	psi-mi:q9hd26-2(display_long)|uniprotkb:GOPC(gene name)|psi-mi:GOPC(display_short)|uniprotkb:CAL(gene name synonym)|uniprotkb:CFTR-associated ligand(gene name synonym)|uniprotkb:FIG(gene name synonym)|uniprotkb:Fused in glioblastoma(gene name synonym)|uniprotkb:PDZ protein interacting specifically with TC10(gene name synonym)	psi-mi:re107_yeast(display_long)|uniprotkb:MER2(gene name synonym)|uniprotkb:J1462(orf name)|uniprotkb:YJR021C(locus name)|uniprotkb:REC107(gene name)|psi-mi:REC107(display_short)|uniprotkb:Meiotic recombination protein 2(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554396|imex:IM-24995-4170	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000047932(gene)|ensembl:ENST00000052569(transcript)|intact:EBI-349832(isoform-parent)|uniprotkb:Q9HD26-2(isoform-parent)	ensemblfungi:YJR021C(gene)|ensemblfungi:YJR021C_mRNA(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0042802"(identical protein binding)|interpro:IPR015159(Mer2)|sgd:S000003782|refseq:NP_012555.1|dip:DIP-5265N	-	-	crc64:46F426AC0DFDFAD0	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:QoEGY54FfmwTrpGVMQN9ASGPgVI9606	rogid:v9kR3rBIptwb/cZE7B5IMAkYWKc559292	intact-crc:573EC7D9180CED35|rigid:GfCz05Or0PqXzJLkD4GZ2URvuhY	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9HD26-2	uniprotkb:P15625	intact:EBI-11102276|ensembl:ENSP00000052569	intact:EBI-18678|uniprotkb:D6VTK8|ensemblfungi:YFL022C	psi-mi:q9hd26-2(display_long)|uniprotkb:GOPC(gene name)|psi-mi:GOPC(display_short)|uniprotkb:CAL(gene name synonym)|uniprotkb:CFTR-associated ligand(gene name synonym)|uniprotkb:FIG(gene name synonym)|uniprotkb:Fused in glioblastoma(gene name synonym)|uniprotkb:PDZ protein interacting specifically with TC10(gene name synonym)	psi-mi:syfa_yeast(display_long)|uniprotkb:FRS2(gene name)|psi-mi:FRS2(display_short)|uniprotkb:Phenylalanyl-tRNA synthetase alpha subunit(gene name synonym)|uniprotkb:YFL022C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554392|imex:IM-24995-4169	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000047932(gene)|ensembl:ENST00000052569(transcript)|intact:EBI-349832(isoform-parent)|uniprotkb:Q9HD26-2(isoform-parent)	refseq:NP_116631.1|sgd:S000001872|ensemblfungi:YFL022C(gene)|ensemblfungi:YFL022C_mRNA(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0002161"(aminoacyl-tRNA editing activity)|go:"GO:0004826"(phenylalanine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006432"(phenylalanyl-tRNA aminoacylation)|go:"GO:0009328"(phenylalanine-tRNA ligase complex)|interpro:IPR002319(Phenylalanyl-tRNA synthetase, class IIc)|interpro:IPR004529(Phenylalanyl-tRNA synthetase, class IIc, alpha subunit)|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR040586|interpro:IPR040725|dip:DIP-5428N|mint:P15625	-	-	crc64:50B7EAC675AB559B	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:QoEGY54FfmwTrpGVMQN9ASGPgVI9606	rogid:hOEtrjcfIHQLY9FwCDb3XI593A4559292	intact-crc:B41F860F82676103|rigid:srErfDzAAmIU+g7YaBH+fja4yiM	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9HD26-2	intact:EBI-11522575	intact:EBI-11102276|ensembl:ENSP00000052569	-	psi-mi:q9hd26-2(display_long)|uniprotkb:GOPC(gene name)|psi-mi:GOPC(display_short)|uniprotkb:CAL(gene name synonym)|uniprotkb:CFTR-associated ligand(gene name synonym)|uniprotkb:FIG(gene name synonym)|uniprotkb:Fused in glioblastoma(gene name synonym)|uniprotkb:PDZ protein interacting specifically with TC10(gene name synonym)	psi-mi:mrpl15(display_short)|psi-mi:EBI-11522575(display_long)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554388|imex:IM-24995-4168	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000047932(gene)|ensembl:ENST00000052569(transcript)|intact:EBI-349832(isoform-parent)|uniprotkb:Q9HD26-2(isoform-parent)	-	-	-	no-uniprot-update:	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:QoEGY54FfmwTrpGVMQN9ASGPgVI9606	rogid:ZU12R+PdYknw8Q1ARUw5V55WN/84932	intact-crc:518A21B630938F4D|rigid:vQuqXIXBBj18kH4Ysh8GtSN2BtU	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P40368	uniprotkb:Q9HCM9-2	intact:EBI-12331|ensemblfungi:YJL061W|uniprotkb:D6VWC1	intact:EBI-11523450|ensembl:ENSP00000365847|ensembl:ENSP00000373095|ensembl:ENSP00000373097|ensembl:ENSP00000379797|ensembl:ENSP00000379800|ensembl:ENSP00000383486|ensembl:ENSP00000387445|ensembl:ENSP00000389198|ensembl:ENSP00000389852|ensembl:ENSP00000392130|ensembl:ENSP00000394353|ensembl:ENSP00000396986|ensembl:ENSP00000398956|ensembl:ENSP00000401071|ensembl:ENSP00000401184|ensembl:ENSP00000404340|ensembl:ENSP00000404904|ensembl:ENSP00000411582|ensembl:ENSP00000412743|ensembl:ENSP00000414525|ensembl:ENSP00000415259	psi-mi:nup82_yeast(display_long)|uniprotkb:NUP82(gene name)|psi-mi:NUP82(display_short)|uniprotkb:YJL061W(locus name)|uniprotkb:J1135(orf name)|uniprotkb:HRB187(orf name)|uniprotkb:Nuclear pore protein NUP82(gene name synonym)	psi-mi:q9hcm9-2(display_long)|uniprotkb:TRIM39(gene name)|psi-mi:TRIM39(display_short)|uniprotkb:RING finger protein 23(gene name synonym)|uniprotkb:RNF23(gene name synonym)|uniprotkb:TFP(gene name synonym)|uniprotkb:Testis-abundant finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 39(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM39(gene name synonym)|uniprotkb:TIM39beta(isoform synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554372|imex:IM-24995-4164	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012474.1|sgd:S000003597|ensemblfungi:YJL061W(gene)|ensemblfungi:YJL061W_mRNA(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0005634"(nucleus)|interpro:IPR037700|rcsb pdb:3PBP|rcsb pdb:3TKN|go:"GO:0005643"(nuclear pore)|go:"GO:0005829"(cytosol)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0044612"(nuclear pore linkers)|go:"GO:0044614"(nuclear pore cytoplasmic filaments)|mint:P40368|dip:DIP-913N	intact:EBI-739510(isoform-parent)|ensembl:ENSG00000204599(gene)|ensembl:ENSG00000206495(gene)|ensembl:ENSG00000224994(gene)|ensembl:ENSG00000226437(gene)|ensembl:ENSG00000229929(gene)|ensembl:ENSG00000230308(gene)|ensembl:ENSG00000232839(gene)|ensembl:ENST00000376659(transcript)|ensembl:ENST00000383601(transcript)|ensembl:ENST00000383603(transcript)|ensembl:ENST00000396548(transcript)|ensembl:ENST00000396551(transcript)|ensembl:ENST00000400644(transcript)|ensembl:ENST00000414015(transcript)|ensembl:ENST00000419790(transcript)|ensembl:ENST00000430502(transcript)|ensembl:ENST00000431272(transcript)|ensembl:ENST00000433900(transcript)|ensembl:ENST00000438076(transcript)|ensembl:ENST00000438859(transcript)|ensembl:ENST00000440117(transcript)|ensembl:ENST00000443109(transcript)|ensembl:ENST00000446397(transcript)|ensembl:ENST00000449318(transcript)|ensembl:ENST00000450778(transcript)|ensembl:ENST00000451132(transcript)|ensembl:ENST00000452705(transcript)|ensembl:ENST00000458607(transcript)|uniprotkb:Q9HCM9-2(isoform-parent)	-	crc64:C379B5E111E26B50	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:g1+jqOMmde8phrNI9H7nFlXwjH0559292	rogid:UfSn2+IVRxtGomVeDGdZpL7mz5I9606	intact-crc:F48655A57D36E0A3|rigid:puDWn9l6XgDWaTpECixgtQCXIGI	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9HCM9-2	uniprotkb:P15732	intact:EBI-11523450|ensembl:ENSP00000365847|ensembl:ENSP00000373095|ensembl:ENSP00000373097|ensembl:ENSP00000379797|ensembl:ENSP00000379800|ensembl:ENSP00000383486|ensembl:ENSP00000387445|ensembl:ENSP00000389198|ensembl:ENSP00000389852|ensembl:ENSP00000392130|ensembl:ENSP00000394353|ensembl:ENSP00000396986|ensembl:ENSP00000398956|ensembl:ENSP00000401071|ensembl:ENSP00000401184|ensembl:ENSP00000404340|ensembl:ENSP00000404904|ensembl:ENSP00000411582|ensembl:ENSP00000412743|ensembl:ENSP00000414525|ensembl:ENSP00000415259	intact:EBI-2097669|uniprotkb:D6VS45|ensemblfungi:YDR059C	psi-mi:q9hcm9-2(display_long)|uniprotkb:TRIM39(gene name)|psi-mi:TRIM39(display_short)|uniprotkb:RING finger protein 23(gene name synonym)|uniprotkb:RNF23(gene name synonym)|uniprotkb:TFP(gene name synonym)|uniprotkb:Testis-abundant finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 39(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM39(gene name synonym)|uniprotkb:TIM39beta(isoform synonym)	psi-mi:ubc5_yeast(display_long)|uniprotkb:UBC5(gene name)|psi-mi:UBC5(display_short)|uniprotkb:Ubiquitin-protein ligase(gene name synonym)|uniprotkb:Ubiquitin carrier protein(gene name synonym)|uniprotkb:YD9609.13C(orf name)|uniprotkb:D4234(orf name)|uniprotkb:YDR059C(locus name)|uniprotkb:E2 ubiquitin-conjugating enzyme 5(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554380|imex:IM-24995-4166	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-739510(isoform-parent)|ensembl:ENSG00000204599(gene)|ensembl:ENSG00000206495(gene)|ensembl:ENSG00000224994(gene)|ensembl:ENSG00000226437(gene)|ensembl:ENSG00000229929(gene)|ensembl:ENSG00000230308(gene)|ensembl:ENSG00000232839(gene)|ensembl:ENST00000376659(transcript)|ensembl:ENST00000383601(transcript)|ensembl:ENST00000383603(transcript)|ensembl:ENST00000396548(transcript)|ensembl:ENST00000396551(transcript)|ensembl:ENST00000400644(transcript)|ensembl:ENST00000414015(transcript)|ensembl:ENST00000419790(transcript)|ensembl:ENST00000430502(transcript)|ensembl:ENST00000431272(transcript)|ensembl:ENST00000433900(transcript)|ensembl:ENST00000438076(transcript)|ensembl:ENST00000438859(transcript)|ensembl:ENST00000440117(transcript)|ensembl:ENST00000443109(transcript)|ensembl:ENST00000446397(transcript)|ensembl:ENST00000449318(transcript)|ensembl:ENST00000450778(transcript)|ensembl:ENST00000451132(transcript)|ensembl:ENST00000452705(transcript)|ensembl:ENST00000458607(transcript)|uniprotkb:Q9HCM9-2(isoform-parent)	refseq:NP_010344.1|sgd:S000002466|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR023313|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|mint:P15732|ensemblfungi:YDR059C(gene)|ensemblfungi:YDR059C_mRNA(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034605"(cellular response to heat)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070628"(proteasome binding)|reactome:R-SCE-8866652|reactome:R-SCE-8866654|reactome:R-SCE-9033241|reactome:R-SCE-983168	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:UfSn2+IVRxtGomVeDGdZpL7mz5I9606	rogid:lhkS9orGIZV1O+L0mEfzlpRvgtk559292	intact-crc:0A95F6AB48ABE70C|rigid:P6Z55egYY1Vj8JOem5y9wSpIWKA	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P38151	uniprotkb:Q9HCM9-2	intact:EBI-12968|uniprotkb:D6VQM8|ensemblfungi:YBR233W	intact:EBI-11523450|ensembl:ENSP00000365847|ensembl:ENSP00000373095|ensembl:ENSP00000373097|ensembl:ENSP00000379797|ensembl:ENSP00000379800|ensembl:ENSP00000383486|ensembl:ENSP00000387445|ensembl:ENSP00000389198|ensembl:ENSP00000389852|ensembl:ENSP00000392130|ensembl:ENSP00000394353|ensembl:ENSP00000396986|ensembl:ENSP00000398956|ensembl:ENSP00000401071|ensembl:ENSP00000401184|ensembl:ENSP00000404340|ensembl:ENSP00000404904|ensembl:ENSP00000411582|ensembl:ENSP00000412743|ensembl:ENSP00000414525|ensembl:ENSP00000415259	psi-mi:pbp2_yeast(display_long)|uniprotkb:YBR1531(orf name)|uniprotkb:YBR233W(locus name)|uniprotkb:PBP2(gene name)|psi-mi:PBP2(display_short)	psi-mi:q9hcm9-2(display_long)|uniprotkb:TRIM39(gene name)|psi-mi:TRIM39(display_short)|uniprotkb:RING finger protein 23(gene name synonym)|uniprotkb:RNF23(gene name synonym)|uniprotkb:TFP(gene name synonym)|uniprotkb:Testis-abundant finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 39(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM39(gene name synonym)|uniprotkb:TIM39beta(isoform synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554376|imex:IM-24995-4165	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000000437|refseq:NP_009792.3|dip:DIP-4947N|ensemblfungi:YBR233W(gene)|ensemblfungi:YBR233W_mRNA(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0051252"(regulation of RNA metabolic process)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR036612	intact:EBI-739510(isoform-parent)|ensembl:ENSG00000204599(gene)|ensembl:ENSG00000206495(gene)|ensembl:ENSG00000224994(gene)|ensembl:ENSG00000226437(gene)|ensembl:ENSG00000229929(gene)|ensembl:ENSG00000230308(gene)|ensembl:ENSG00000232839(gene)|ensembl:ENST00000376659(transcript)|ensembl:ENST00000383601(transcript)|ensembl:ENST00000383603(transcript)|ensembl:ENST00000396548(transcript)|ensembl:ENST00000396551(transcript)|ensembl:ENST00000400644(transcript)|ensembl:ENST00000414015(transcript)|ensembl:ENST00000419790(transcript)|ensembl:ENST00000430502(transcript)|ensembl:ENST00000431272(transcript)|ensembl:ENST00000433900(transcript)|ensembl:ENST00000438076(transcript)|ensembl:ENST00000438859(transcript)|ensembl:ENST00000440117(transcript)|ensembl:ENST00000443109(transcript)|ensembl:ENST00000446397(transcript)|ensembl:ENST00000449318(transcript)|ensembl:ENST00000450778(transcript)|ensembl:ENST00000451132(transcript)|ensembl:ENST00000452705(transcript)|ensembl:ENST00000458607(transcript)|uniprotkb:Q9HCM9-2(isoform-parent)	-	crc64:638846509BCE1840	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:zcN9K+pivnit4l3Cl75wfk5F4VI559292	rogid:UfSn2+IVRxtGomVeDGdZpL7mz5I9606	intact-crc:D8F72ADD56BFE67C|rigid:bVlRgMoN5MAv7jTlzTgLikI5FNw	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9HD26-2	uniprotkb:P27882	intact:EBI-11102276|ensembl:ENSP00000052569	intact:EBI-6621|uniprotkb:D6VUG4|ensemblfungi:YGR029W	psi-mi:q9hd26-2(display_long)|uniprotkb:GOPC(gene name)|psi-mi:GOPC(display_short)|uniprotkb:CAL(gene name synonym)|uniprotkb:CFTR-associated ligand(gene name synonym)|uniprotkb:FIG(gene name synonym)|uniprotkb:Fused in glioblastoma(gene name synonym)|uniprotkb:PDZ protein interacting specifically with TC10(gene name synonym)	psi-mi:erv1_yeast(display_long)|uniprotkb:Essential for respiration and vegetative growth protein 1(gene name synonym)|uniprotkb:14 kDa regulatory protein(gene name synonym)|uniprotkb:ERV1(gene name)|psi-mi:ERV1(display_short)|uniprotkb:YGR029W(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554384|imex:IM-24995-4167	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000047932(gene)|ensembl:ENST00000052569(transcript)|intact:EBI-349832(isoform-parent)|uniprotkb:Q9HD26-2(isoform-parent)	refseq:NP_011543.4|sgd:S000003261|interpro:IPR017905|interpro:IPR036774|mint:P27882|interpro:IPR039799|ensemblfungi:YGR029W(gene)|ensemblfungi:YGR029W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0016971"(flavin-linked sulfhydryl oxidase activity)|go:"GO:0016972"(thiol oxidase activity)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0045041"(protein import into mitochondrial intermembrane space)|go:"GO:0050660"(flavin adenine dinucleotide binding)|rcsb pdb:3W4Y|rcsb pdb:4E0H|rcsb pdb:4E0I	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:QoEGY54FfmwTrpGVMQN9ASGPgVI9606	rogid:nYYS2xiutIkSeWN8DabWui0hzr4559292	intact-crc:50E8C88B2998B5F4|rigid:xOqd6gwSBIX/gIXoj2DzzoCzauI	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P25375	uniprotkb:Q9NPC3	intact:EBI-13932|uniprotkb:E9P942|uniprotkb:D6VQW0|ensemblfungi:YCL057W	intact:EBI-745269|ensembl:ENSP00000337396|ensembl:ENSP00000351810|ensembl:ENSP00000381226|ensembl:ENSP00000381229|ensembl:ENSP00000381235|ensembl:ENSP00000409896	psi-mi:prtd_yeast(display_long)|uniprotkb:PRD1(gene name)|psi-mi:PRD1(display_short)|uniprotkb:YCL057W(locus name)|uniprotkb:YCL57W(orf name)|uniprotkb:Protease D(gene name synonym)|uniprotkb:Proteinase yscD(gene name synonym)|uniprotkb:Oligopeptidase YSCD(gene name synonym)	psi-mi:cip1_human(display_long)|uniprotkb:Cyclin-B1-interacting protein 1(gene name synonym)|uniprotkb:Human enhancer of invasion 10(gene name synonym)|uniprotkb:CCNB1IP1(gene name)|psi-mi:CCNB1IP1(display_short)|uniprotkb:C14orf18(gene name synonym)|uniprotkb:HEI10(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase CCNB1IP1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554420|imex:IM-24995-4176	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009874.1|sgd:S000000562|ensemblfungi:YCL057W(gene)|ensemblfungi:YCL057W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006508"(proteolysis)|go:"GO:0006518"(peptide metabolic process)|go:"GO:0046872"(metal ion binding)|interpro:IPR001567(Peptidase M3A and M3B, thimet/oligopeptidase F)|interpro:IPR024077|interpro:IPR024079|interpro:IPR024080|reactome:R-SCE-983168|mint:P25375|dip:DIP-4938N	refseq:NP_067001.3|refseq:NP_878269.1|refseq:NP_878272.1|ensembl:ENSG00000100814(gene)|ensembl:ENST00000353689(transcript)|ensembl:ENST00000358932(transcript)|ensembl:ENST00000398160(transcript)|ensembl:ENST00000398163(transcript)|ensembl:ENST00000398169(transcript)|ensembl:ENST00000437553(transcript)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001825"(blastocyst formation)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0007286"(spermatid development)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051026"(chiasma assembly)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR042448	-	crc64:340910B7FDAFBE37	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:WXFCl27lNmdlkUaDqmVZl0u4bGg559292	rogid:UyF392Md+IuOz5wp9kW2Pjr2ZzY9606	intact-crc:E486D9935304D10E|rigid:81gO47TC1Ngvuv+dQnrkjbeuJPc	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q12161	uniprotkb:Q9NTW7	intact:EBI-34372|uniprotkb:D6W213|ensemblfungi:YOL054W	intact:EBI-711679|uniprotkb:Q9NTS7|uniprotkb:Q9NVH4|ensembl:ENSP00000355179|intact:EBI-10965088|intact:EBI-8637652|intact:MINT-8162399|intact:EBI-745730|uniprotkb:A2A2N4|uniprotkb:Q53H69|uniprotkb:Q53XQ1|uniprotkb:Q5JWM0|uniprotkb:Q5JWM1|uniprotkb:Q8WU98|uniprotkb:Q9H9P1|uniprotkb:Q9NPA5	psi-mi:psh1_yeast(display_long)|uniprotkb:PSH1(gene name)|psi-mi:PSH1(display_short)|uniprotkb:POB3/SPT16 histone-associated protein 1(gene name synonym)|uniprotkb:O1263(orf name)|uniprotkb:YOL054W(locus name)	psi-mi:zf64b_human(display_long)|uniprotkb:Zinc finger protein 338(gene name synonym)|uniprotkb:ZFP64(gene name)|psi-mi:ZFP64(display_short)|uniprotkb:ZNF338(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554416|imex:IM-24995-4175	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014587.1|sgd:S000005415|mint:Q12161|dip:DIP-6481N|ensemblfungi:YOL054W(gene)|ensemblfungi:YOL054W_mRNA(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907	refseq:NP_955459.2|ensembl:ENSG00000020256(gene)|ensembl:ENST00000361387(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|rcsb pdb:1X5W|rcsb pdb:2DMD|interpro:IPR036236|refseq:NP_001306075.1|refseq:NP_060667.2|refseq:NP_071371.3|refseq:NP_955458.1	-	crc64:CE0ECBCB6D465554	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2019/04/15	rogid:AvPMRd/GjfaTyQjEfMPhBVcvOs4559292	rogid:aTPOj1Ms8ghVMxTJUwnDUyonUQU9606	intact-crc:8560C940D7CDE61C|rigid:H1grh63KX7jGkuDU2e4yb81EM2Q	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9HD26-2	uniprotkb:P25299	intact:EBI-11102276|ensembl:ENSP00000052569	intact:EBI-15640|uniprotkb:D6VU95|ensemblfungi:YGL044C	psi-mi:q9hd26-2(display_long)|uniprotkb:GOPC(gene name)|psi-mi:GOPC(display_short)|uniprotkb:CAL(gene name synonym)|uniprotkb:CFTR-associated ligand(gene name synonym)|uniprotkb:FIG(gene name synonym)|uniprotkb:Fused in glioblastoma(gene name synonym)|uniprotkb:PDZ protein interacting specifically with TC10(gene name synonym)	psi-mi:rna15_yeast(display_long)|uniprotkb:YGL044C(locus name)|uniprotkb:RNA15(gene name)|psi-mi:RNA15(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554400|imex:IM-24995-4171	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000047932(gene)|ensembl:ENST00000052569(transcript)|intact:EBI-349832(isoform-parent)|uniprotkb:Q9HD26-2(isoform-parent)	refseq:NP_011471.1|sgd:S000003012|ensemblfungi:YGL044C(gene)|ensemblfungi:YGL044C_mRNA(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0005849"(mRNA cleavage factor complex)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0072423"(response to DNA damage checkpoint signaling)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR026896|interpro:IPR035979|interpro:IPR038192|rcsb pdb:2KM8|rcsb pdb:2L9B|rcsb pdb:2X1A|rcsb pdb:2X1B|rcsb pdb:2X1F|dip:DIP-1489N|mint:P25299	-	-	crc64:10053B8648A71ECB	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:QoEGY54FfmwTrpGVMQN9ASGPgVI9606	rogid:TqfxsTHAh9CPJJ6Q7uH6kz988hk559292	intact-crc:7B886A01D6B28E68|rigid:uWGqexURRYxTTx+kiSeq1kdSbkc	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P37263	uniprotkb:Q9NP64	intact:EBI-21659|uniprotkb:D6VR87|ensemblfungi:YCR087C-A	intact:EBI-746345|uniprotkb:Q6PKH4|uniprotkb:Q9NYG4|uniprotkb:Q9P0M8|uniprotkb:D3DPN4|ensembl:ENSP00000343557|ensembl:ENSP00000362819|uniprotkb:B4DY38	psi-mi:yc16_yeast(display_long)|uniprotkb:YCRX16C(orf name)|uniprotkb:YCR087C-A(locus name)	psi-mi:no40_human(display_long)|uniprotkb:Zinc finger CCHC domain-containing protein 17(gene name synonym)|uniprotkb:Putative S1 RNA-binding domain protein(gene name synonym)|uniprotkb:Pnn-interacting nucleolar protein(gene name synonym)|uniprotkb:ZCCHC17(gene name)|psi-mi:ZCCHC17(display_short)|uniprotkb:HSPC243(orf name)|uniprotkb:HSPC251(orf name)|uniprotkb:LDC4(orf name)|uniprotkb:PS1D(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554408|imex:IM-24995-4173	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010011.1|sgd:S000007223|mint:P37263|dip:DIP-4536N|ensemblfungi:YCR087C-A(gene)|ensemblfungi:YCR087C-A_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR014898(Zinc finger, C2H2, LYAR-type)|interpro:IPR036236|interpro:IPR039999	refseq:NP_001269495.1|refseq:NP_001269496.1|refseq:NP_001269497.1|refseq:NP_001269498.1|refseq:NP_001269499.1|refseq:NP_001269500.1|refseq:NP_001269501.1|refseq:NP_001269502.1|refseq:NP_001269503.1|refseq:XP_006710744.1|refseq:NP_057589.2|refseq:XP_011539869.1|ensembl:ENSG00000121766(gene)|ensembl:ENST00000344147(transcript)|ensembl:ENST00000373714(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0042802"(identical protein binding)|go:"GO:0043489"(RNA stabilization)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR003029(S1, RNA binding)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR022967|interpro:IPR037320|mint:Q9NP64|rcsb pdb:2CQO	-	crc64:B5B3B4CA37B82042	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:I7iIzRqPZAKdWQSe/IeGsW0qQcU559292	rogid:e71wAulRWX6cM59s3g8R42PWXeU9606	intact-crc:2F765A6F3C480F8D|rigid:Ml0Q/8mbm2fJgykAKfM9sgQUtFs	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9NNX1-2	uniprotkb:Q04307	intact:EBI-11535232|ensembl:ENSP00000357841	intact:EBI-15858|uniprotkb:Q2VQW5|ensemblfungi:YDR045C|uniprotkb:D6VS33	psi-mi:q9nnx1-2(display_long)|uniprotkb:TUFT1(gene name)|psi-mi:TUFT1(display_short)	psi-mi:rpc10_yeast(display_long)|uniprotkb:RPC11(gene name)|psi-mi:RPC11(display_short)|uniprotkb:YDR045C(locus name)|uniprotkb:YD9609.01C(orf name)|uniprotkb:RNA polymerase III subunit C11(gene name synonym)|uniprotkb:DNA-directed RNA polymerases III 12.5 kDa polypeptide(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554404|imex:IM-24995-4172	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-2557363(isoform-parent)|ensembl:ENSG00000143367(gene)|ensembl:ENST00000368848(transcript)|uniprotkb:Q9NNX1-2(isoform-parent)	ensemblfungi:YDR045C(gene)|refseq:NP_010330.1|sgd:S000002452|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006386"(termination of RNA polymerase III transcription)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042779"(tRNA 3'-trailer cleavage)|go:"GO:0042797"(tRNA transcription by RNA polymerase III)|interpro:IPR001222(Zinc finger, TFIIS-type)|interpro:IPR001529(DNA-directed RNA polymerase, M/15 kDa subunit)|interpro:IPR012164(DNA-directed RNA polymerase, subunit C11/M/9)|interpro:IPR019761|interpro:IPR034014|rcsb pdb:3QT1|ensemblfungi:YDR045C_mRNA(transcript)|rcsb pdb:5FJ8|rcsb pdb:5FJ9|rcsb pdb:5FJA|rcsb pdb:6CNB|rcsb pdb:6CNC|rcsb pdb:6CND|rcsb pdb:6CNF|rcsb pdb:6EU0|rcsb pdb:6EU2|rcsb pdb:6EU3|rcsb pdb:6F40|rcsb pdb:6F41|rcsb pdb:6F42|rcsb pdb:6F44|rcsb pdb:6TUT|reactome:R-SCE-76061|reactome:R-SCE-76066|rcsb pdb:6EU1|dip:DIP-887N|mint:Q04307	-	-	crc64:E4AA802EC9F92230	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Xt8rl/ePRyc25U9+KY9b8o1IcNs9606	rogid:G2fIQbptabHIUI224iPtTJF+dIs559292	intact-crc:42B8393C73A8C5CC|rigid:LHE5xu/Xg2ztWFBt6i7YHI5S7XU	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9NP66	uniprotkb:P40956	intact:EBI-740641|ensembl:ENSP00000336856|ensembl:ENSP00000371133|uniprotkb:A6NHY3|uniprotkb:Q53G31|uniprotkb:Q9NSF6|uniprotkb:D3DW78	intact:EBI-7968|uniprotkb:D6VTX2|ensemblfungi:YGL181W	psi-mi:hm20a_human(display_long)|uniprotkb:HMG box-containing protein 20A(gene name synonym)|uniprotkb:HMG domain-containing protein HMGX1(gene name synonym)|uniprotkb:HMG20A(gene name)|psi-mi:HMG20A(display_short)|uniprotkb:HMGX1(gene name synonym)|uniprotkb:HMGXB1(gene name synonym)|uniprotkb:HMG domain-containing protein 1(gene name synonym)	psi-mi:gts1_yeast(display_long)|uniprotkb:YGL181W(locus name)|uniprotkb:GTS1(gene name)|psi-mi:GTS1(display_short)|uniprotkb:LSR1(gene name synonym)|uniprotkb:Protein LSR1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554412|imex:IM-24995-4174	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060670.1|ensembl:ENSG00000140382(gene)|ensembl:ENST00000336216(transcript)|ensembl:ENST00000381714(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0033234"(negative regulation of protein sumoylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045665"(negative regulation of neuron differentiation)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR036910|mint:Q9NP66|refseq:NP_001291433.1|refseq:NP_001291434.1|refseq:XP_011519460.1	refseq:NP_011334.1|sgd:S000003149|mint:P40956|dip:DIP-2746N|ensemblfungi:YGL181W(gene)|ensemblfungi:YGL181W_mRNA(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0006897"(endocytosis)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010512"(negative regulation of phosphatidylinositol biosynthetic process)|go:"GO:0030479"(actin cortical patch)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR037278|interpro:IPR038508	-	-	crc64:D687E3BF6B620795	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:LhilayeP+xv97pbYzIA8yMvwUbc9606	rogid:8kgpssCRrHiTHsFaOH2nDK6EIjk559292	intact-crc:B638B58DCD510116|rigid:KFGEdcORXXfJ143rC9druKM9Cf8	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P32502	uniprotkb:Q9NQC3-3	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	intact:EBI-11526335|ensembl:ENSP00000378107	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:q9nqc3-3(display_long)|uniprotkb:Foocen(gene name synonym)|uniprotkb:KIAA0886(gene name synonym)|uniprotkb:NOGO(gene name synonym)|uniprotkb:Neurite outgrowth inhibitor(gene name synonym)|uniprotkb:Neuroendocrine-specific protein(gene name synonym)|uniprotkb:Neuroendocrine-specific protein C homolog(gene name synonym)|uniprotkb:RTN-x(gene name synonym)|uniprotkb:Reticulon-5(gene name synonym)|uniprotkb:My043(orf name)|uniprotkb:SP1507(orf name)|uniprotkb:Foocen-S(isoform synonym)|uniprotkb:Nogo-C(isoform synonym)|uniprotkb:RTN4(gene name)|psi-mi:RTN4(display_short)|uniprotkb:RTN4C(isoform synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554452|imex:IM-24995-4184	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731	intact:EBI-715945(isoform-parent)|ensembl:ENSG00000115310(gene)|ensembl:ENST00000394609(transcript)	-	crc64:A5409FAF1594854C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	rogid:Iq/LlFtXjFyIIfxZ1l3NTKURpyA9606	intact-crc:23BD1E6DA5ADB0C5|rigid:vyF0xIDaWGKzxa2afM0/ZpIdraI	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
intact:EBI-11522208	uniprotkb:Q9NPJ6	-	intact:EBI-394607|uniprotkb:Q9BS95|uniprotkb:Q9NYR5|uniprotkb:Q53GB4|uniprotkb:Q53H68|uniprotkb:Q5T912|uniprotkb:Q6FHC4|uniprotkb:Q6IA79|uniprotkb:B4DX67|ensembl:ENSP00000258648	psi-mi:ylr445w(display_short)|psi-mi:EBI-11522208(display_long)	psi-mi:med4_human(display_long)|uniprotkb:HSPC126(orf name)|uniprotkb:DRIP36(gene name synonym)|uniprotkb:MED4(gene name)|psi-mi:MED4(display_short)|uniprotkb:ARC36(gene name synonym)|uniprotkb:Mediator complex subunit 4(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex 36 kDa component(gene name synonym)|uniprotkb:Activator-recruited cofactor 36 kDa component(gene name synonym)|uniprotkb:TRAP/SMCC/PC2 subunit p36 subunit(gene name synonym)|uniprotkb:VDRIP(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554448|imex:IM-24995-4183	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001257558.1|refseq:NP_054885.1|ensembl:ENSG00000136146(gene)|ensembl:ENST00000258648(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0070847"(core mediator complex)|interpro:IPR019258|mint:Q9NPJ6|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340	-	no-uniprot-update:	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:kUe7etYjGLH6i6KZ5N2LXUnjAf04932	rogid:Bept2Oec50gruA9e4pf+eEUiANM9606	intact-crc:747CC28D85A35851|rigid:5GC7wSGOu6bpZglvGPIeDsMqEms	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9NPJ6	uniprotkb:P32502	intact:EBI-394607|uniprotkb:Q9BS95|uniprotkb:Q9NYR5|uniprotkb:Q53GB4|uniprotkb:Q53H68|uniprotkb:Q5T912|uniprotkb:Q6FHC4|uniprotkb:Q6IA79|uniprotkb:B4DX67|ensembl:ENSP00000258648	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:med4_human(display_long)|uniprotkb:HSPC126(orf name)|uniprotkb:DRIP36(gene name synonym)|uniprotkb:MED4(gene name)|psi-mi:MED4(display_short)|uniprotkb:ARC36(gene name synonym)|uniprotkb:Mediator complex subunit 4(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex 36 kDa component(gene name synonym)|uniprotkb:Activator-recruited cofactor 36 kDa component(gene name synonym)|uniprotkb:TRAP/SMCC/PC2 subunit p36 subunit(gene name synonym)|uniprotkb:VDRIP(gene name synonym)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554444|imex:IM-24995-4182	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001257558.1|refseq:NP_054885.1|ensembl:ENSG00000136146(gene)|ensembl:ENST00000258648(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0070847"(core mediator complex)|interpro:IPR019258|mint:Q9NPJ6|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731	-	-	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Bept2Oec50gruA9e4pf+eEUiANM9606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:F6BCA176275CA560|rigid:+53+PRs9H9BVSg/T98CNrYqG7DA	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9NPI6	uniprotkb:Q3E7X9	intact:EBI-374238|ensembl:ENSP00000476386|uniprotkb:B4DHN9|uniprotkb:U3KQM8	intact:EBI-2343611|uniprotkb:D6W2M5|uniprotkb:P02380|ensemblfungi:YOR167C	psi-mi:dcp1a_human(display_long)|uniprotkb:DCP1A(gene name)|psi-mi:DCP1A(display_short)|uniprotkb:Transcription factor SMIF(gene name synonym)|uniprotkb:Smad4-interacting transcriptional co-activator(gene name synonym)|uniprotkb:SMIF(gene name synonym)	psi-mi:rs28a_yeast(display_long)|uniprotkb:RPS28A(gene name)|psi-mi:RPS28A(display_short)|uniprotkb:RPS33(gene name synonym)|uniprotkb:RPS33A(gene name synonym)|uniprotkb:S33(gene name synonym)|uniprotkb:YS27(gene name synonym)|uniprotkb:O3600(orf name)|uniprotkb:YOR167C(locus name)|uniprotkb:Small ribosomal subunit protein eS28-A(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554424|imex:IM-24995-4177	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000272886(gene)|ensembl:ENST00000610213(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016020"(membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0019894"(kinesin binding)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|interpro:IPR010334(Dcp1-like decapping)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR031953|mint:Q9NPI6|rcsb pdb:2WX3|rcsb pdb:4B6H|reactome:R-HSA-430039|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-975957|refseq:NP_060873.4|refseq:NP_001277133.1|refseq:NP_001277136.1|refseq:NP_001277134.1|refseq:NP_001277135.1|dip:DIP-31292N	refseq:NP_014810.1|sgd:S000005693|dip:DIP-29384N|ensemblfungi:YOR167C(gene)|ensemblfungi:YOR167C_mRNA(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0006407"(rRNA export from nucleus)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0030490"(maturation of SSU-rRNA)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|interpro:IPR000289(Ribosomal protein S28e)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR028626|rcsb pdb:3J6X|rcsb pdb:3J6Y|rcsb pdb:3J77|rcsb pdb:3J78|rcsb pdb:4U3M|rcsb pdb:4U3N|rcsb pdb:4U3U|rcsb pdb:4U4N|rcsb pdb:4U4O|rcsb pdb:4U4Q|rcsb pdb:4U4R|rcsb pdb:4U4U|rcsb pdb:4U4Y|rcsb pdb:4U4Z|rcsb pdb:4U50|rcsb pdb:4U51|rcsb pdb:4U52|rcsb pdb:4U53|rcsb pdb:4U55|rcsb pdb:4U56|rcsb pdb:4U6F|rcsb pdb:4V6I|rcsb pdb:4V7R|rcsb pdb:4V88|rcsb pdb:4V8Y|rcsb pdb:4V8Z|rcsb pdb:4V92|rcsb pdb:5DAT|rcsb pdb:5DC3|rcsb pdb:5DGE|rcsb pdb:5DGF|rcsb pdb:5DGV|rcsb pdb:5FCI|rcsb pdb:5FCJ|rcsb pdb:5I4L|rcsb pdb:5JPQ|rcsb pdb:5JUO|rcsb pdb:5JUP|rcsb pdb:5JUS|rcsb pdb:5JUT|rcsb pdb:5JUU|rcsb pdb:5LYB|rcsb pdb:5MEI|rcsb pdb:5NDG|rcsb pdb:5NDV|rcsb pdb:5NDW|rcsb pdb:5OBM|rcsb pdb:5ON6|rcsb pdb:5TBW|rcsb pdb:5TGA|rcsb pdb:5TGM|rcsb pdb:5TZS|rcsb pdb:5WLC|rcsb pdb:5WYJ|rcsb pdb:5WYK|rcsb pdb:6FAI|rcsb pdb:6GQ1|rcsb pdb:6GQB|rcsb pdb:6GQV|rcsb pdb:6HHQ|rcsb pdb:6I7O|rcsb pdb:6KE6|rcsb pdb:6LQP|rcsb pdb:6LQQ|rcsb pdb:6LQR|rcsb pdb:6LQS|rcsb pdb:6LQT|rcsb pdb:6LQU|rcsb pdb:6LQV|rcsb pdb:6Q8Y|rcsb pdb:6RBD|rcsb pdb:6RBE|rcsb pdb:6S47|rcsb pdb:6T4Q|rcsb pdb:6TB3|rcsb pdb:6TNU|rcsb pdb:6WDR|rcsb pdb:6WOO|rcsb pdb:6Y7C|rcsb pdb:6Z6J|rcsb pdb:6Z6K|rcsb pdb:6ZQA|rcsb pdb:6ZQB|rcsb pdb:6ZQC|rcsb pdb:6ZQD|rcsb pdb:6ZQE|rcsb pdb:6ZQF|rcsb pdb:6ZQG|rcsb pdb:6ZVI|rcsb pdb:7A1G|rcsb pdb:7AJT|rcsb pdb:7AJU|rcsb pdb:7B7D|rcsb pdb:7NRC|rcsb pdb:7NRD	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2018/09/18	rogid:KIg2pPmAEIiig2SXAJNziN91oCY9606	rogid:gvC4obwu3fwLTPwW+gv2KPlZ02A559292	intact-crc:45CC5D9BFBC9A2AD|rigid:vROv6ZoiAAm/VhBjEm6qTGKgggk	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9NPJ6	uniprotkb:P39518	intact:EBI-394607|uniprotkb:Q9BS95|uniprotkb:Q9NYR5|uniprotkb:Q53GB4|uniprotkb:Q53H68|uniprotkb:Q5T912|uniprotkb:Q6FHC4|uniprotkb:Q6IA79|uniprotkb:B4DX67|ensembl:ENSP00000258648	intact:EBI-10082|uniprotkb:D3DLR3|ensemblfungi:YER015W	psi-mi:med4_human(display_long)|uniprotkb:HSPC126(orf name)|uniprotkb:DRIP36(gene name synonym)|uniprotkb:MED4(gene name)|psi-mi:MED4(display_short)|uniprotkb:ARC36(gene name synonym)|uniprotkb:Mediator complex subunit 4(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex 36 kDa component(gene name synonym)|uniprotkb:Activator-recruited cofactor 36 kDa component(gene name synonym)|uniprotkb:TRAP/SMCC/PC2 subunit p36 subunit(gene name synonym)|uniprotkb:VDRIP(gene name synonym)	psi-mi:lcf2_yeast(display_long)|uniprotkb:YER015W(locus name)|uniprotkb:FAA2(gene name)|psi-mi:FAA2(display_short)|uniprotkb:FAM1(gene name synonym)|uniprotkb:Long-chain acyl-CoA synthetase 2(gene name synonym)|uniprotkb:Fatty acid activator 2(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554436|imex:IM-24995-4180	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001257558.1|refseq:NP_054885.1|ensembl:ENSG00000136146(gene)|ensembl:ENST00000258648(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0070847"(core mediator complex)|interpro:IPR019258|mint:Q9NPJ6|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340	sgd:S000000817|ensemblfungi:YER015W_mRNA(transcript)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0004467"(long-chain fatty acid-CoA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0015910"(long-chain fatty acid import into peroxisome)|go:"GO:0015916"(fatty-acyl-CoA transport)|go:"GO:0016020"(membrane)|go:"GO:0031956"(medium-chain fatty acid-CoA ligase activity)|go:"GO:0031957"(very long-chain fatty acid-CoA ligase activity)|go:"GO:0042760"(very long-chain fatty acid catabolic process)|go:"GO:0102391"(decanoate-CoA ligase activity)|ensemblfungi:YER015W(gene)|interpro:IPR020845|interpro:IPR000873(AMP-dependent synthetase and ligase)|reactome:R-SCE-75876|refseq:NP_010931.3|dip:DIP-6565N	-	-	crc64:1E023C18682805BC	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Bept2Oec50gruA9e4pf+eEUiANM9606	rogid:N0W+wPvCsl01y0k8hJZ156LztOo559292	intact-crc:BABE978A7CED4961|rigid:i1z/5yTyyQ+u3OtNUB+vUE5MzCI	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P48837	uniprotkb:Q9NPJ6	intact:EBI-12324|ensemblfungi:YGR119C|uniprotkb:D6VUQ0	intact:EBI-394607|uniprotkb:Q9BS95|uniprotkb:Q9NYR5|uniprotkb:Q53GB4|uniprotkb:Q53H68|uniprotkb:Q5T912|uniprotkb:Q6FHC4|uniprotkb:Q6IA79|uniprotkb:B4DX67|ensembl:ENSP00000258648	psi-mi:nup57_yeast(display_long)|uniprotkb:NUP57(gene name)|psi-mi:NUP57(display_short)|uniprotkb:YGR119C(locus name)|uniprotkb:G6320(orf name)|uniprotkb:Nuclear pore protein NUP57(gene name synonym)	psi-mi:med4_human(display_long)|uniprotkb:HSPC126(orf name)|uniprotkb:DRIP36(gene name synonym)|uniprotkb:MED4(gene name)|psi-mi:MED4(display_short)|uniprotkb:ARC36(gene name synonym)|uniprotkb:Mediator complex subunit 4(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex 36 kDa component(gene name synonym)|uniprotkb:Activator-recruited cofactor 36 kDa component(gene name synonym)|uniprotkb:TRAP/SMCC/PC2 subunit p36 subunit(gene name synonym)|uniprotkb:VDRIP(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554432|imex:IM-24995-4179	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YGR119C(gene)|ensemblfungi:YGR119C_mRNA(transcript)|go:"GO:0005643"(nuclear pore)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036228"(protein localization to nuclear inner membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0051028"(mRNA transport)|interpro:IPR024864|interpro:IPR025574|interpro:IPR025712|refseq:NP_011634.1|sgd:S000003351|mint:P48837|dip:DIP-866N	refseq:NP_001257558.1|refseq:NP_054885.1|ensembl:ENSG00000136146(gene)|ensembl:ENST00000258648(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0070847"(core mediator complex)|interpro:IPR019258|mint:Q9NPJ6|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:ultDTflWHx7n/y2FrlWFf+lBKmw559292	rogid:Bept2Oec50gruA9e4pf+eEUiANM9606	intact-crc:DCE698E19F8853AE|rigid:E4yC3H7ZNEmr16/ErOuydE6jpDM	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P40325	uniprotkb:Q9NPJ6	intact:EBI-23614|uniprotkb:D6VV46|ensemblfungi:YGR268C	intact:EBI-394607|uniprotkb:Q9BS95|uniprotkb:Q9NYR5|uniprotkb:Q53GB4|uniprotkb:Q53H68|uniprotkb:Q5T912|uniprotkb:Q6FHC4|uniprotkb:Q6IA79|uniprotkb:B4DX67|ensembl:ENSP00000258648	psi-mi:hua1_yeast(display_long)|uniprotkb:HUA1(gene name)|psi-mi:HUA1(display_short)|uniprotkb:YGR268C(locus name)	psi-mi:med4_human(display_long)|uniprotkb:HSPC126(orf name)|uniprotkb:DRIP36(gene name synonym)|uniprotkb:MED4(gene name)|psi-mi:MED4(display_short)|uniprotkb:ARC36(gene name synonym)|uniprotkb:Mediator complex subunit 4(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex 36 kDa component(gene name synonym)|uniprotkb:Activator-recruited cofactor 36 kDa component(gene name synonym)|uniprotkb:TRAP/SMCC/PC2 subunit p36 subunit(gene name synonym)|uniprotkb:VDRIP(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554428|imex:IM-24995-4178	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003500|refseq:NP_011784.3|dip:DIP-1987N|ensemblfungi:YGR268C(gene)|ensemblfungi:YGR268C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|interpro:IPR038910	refseq:NP_001257558.1|refseq:NP_054885.1|ensembl:ENSG00000136146(gene)|ensembl:ENST00000258648(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0070847"(core mediator complex)|interpro:IPR019258|mint:Q9NPJ6|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340	-	crc64:78029FD484168793	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:xliNG9XUWbYRd0Nbu+xzCgxNrAs559292	rogid:Bept2Oec50gruA9e4pf+eEUiANM9606	intact-crc:C35EAB7C2011B4D9|rigid:YjjL0fdYfJwMYhA7NMox2pVSZCI	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P48232	uniprotkb:Q9NPJ6	intact:EBI-28775|uniprotkb:D6W193|ensemblfungi:YNL086W	intact:EBI-394607|uniprotkb:Q9BS95|uniprotkb:Q9NYR5|uniprotkb:Q53GB4|uniprotkb:Q53H68|uniprotkb:Q5T912|uniprotkb:Q6FHC4|uniprotkb:Q6IA79|uniprotkb:B4DX67|ensembl:ENSP00000258648	psi-mi:snapn_yeast(display_long)|uniprotkb:YNL086W(locus name)|uniprotkb:N2254(orf name)|uniprotkb:SNN1(gene name)|psi-mi:SNN1(display_short)|uniprotkb:SNAPIN-like protein 1(gene name synonym)	psi-mi:med4_human(display_long)|uniprotkb:HSPC126(orf name)|uniprotkb:DRIP36(gene name synonym)|uniprotkb:MED4(gene name)|psi-mi:MED4(display_short)|uniprotkb:ARC36(gene name synonym)|uniprotkb:Mediator complex subunit 4(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex 36 kDa component(gene name synonym)|uniprotkb:Activator-recruited cofactor 36 kDa component(gene name synonym)|uniprotkb:TRAP/SMCC/PC2 subunit p36 subunit(gene name synonym)|uniprotkb:VDRIP(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554440|imex:IM-24995-4181	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014313.1|sgd:S000005030|dip:DIP-1188N|mint:P48232|ensemblfungi:YNL086W(gene)|ensemblfungi:YNL086W_mRNA(transcript)|go:"GO:0005768"(endosome)|go:"GO:0007032"(endosome organization)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0032880"(regulation of protein localization)	refseq:NP_001257558.1|refseq:NP_054885.1|ensembl:ENSG00000136146(gene)|ensembl:ENST00000258648(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0070847"(core mediator complex)|interpro:IPR019258|mint:Q9NPJ6|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340	-	crc64:33200D2F0F729DA1	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:XCPaHuGC9oKD/3W0gY5ZY8jKtFs559292	rogid:Bept2Oec50gruA9e4pf+eEUiANM9606	intact-crc:7A9D0B14D9769C32|rigid:ZUrZqOehAmrIHlIcTMuqZVSdGYo	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P32502	uniprotkb:Q9NRG1	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	intact:EBI-739759|uniprotkb:Q53HA7|uniprotkb:Q59EL9|uniprotkb:Q5VV18|uniprotkb:Q5VV20|uniprotkb:B7Z1Z3|ensembl:ENSP00000318602	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:prdc1_human(display_long)|uniprotkb:PRTFDC1(gene name)|psi-mi:PRTFDC1(display_short)|uniprotkb:HHGP(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554484|imex:IM-24995-4192	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731	refseq:NP_001269715.1|refseq:NP_064585.1|ensembl:ENSG00000099256(gene)|ensembl:ENST00000320152(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0006166"(purine ribonucleoside salvage)|go:"GO:0042803"(protein homodimerization activity)|interpro:IPR000836(Phosphoribosyltransferase)|interpro:IPR005904(Hypoxanthine phosphoribosyl transferase)|interpro:IPR029057|rcsb pdb:2JBH	-	crc64:A5409FAF1594854C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	rogid:grTZnSalFILRSeeZBjM1mTtF0xo9606	intact-crc:025C1644A51BD29C|rigid:zxrZ2roKd1hs5E5IEnuM1CbHXBk	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9NRF8	uniprotkb:Q02872	intact:EBI-740874|ensembl:ENSP00000352222|ensembl:ENSP00000369590|ensembl:ENSP00000401264|uniprotkb:Q9BRI0|uniprotkb:Q9H809|uniprotkb:Q9H8K9|uniprotkb:B3KWM2	intact:EBI-38045|uniprotkb:D6W3Q9|ensemblfungi:YPL108W	psi-mi:pyrg2_human(display_long)|uniprotkb:UTP--ammonia ligase 2(gene name synonym)|uniprotkb:CTP synthetase 2(gene name synonym)|uniprotkb:CTPS2(gene name)|psi-mi:CTPS2(display_short)	psi-mi:yp108_yeast(display_long)|uniprotkb:YPL108W(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554480|imex:IM-24995-4191	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000047230(gene)|refseq:NP_001137474.1|refseq:NP_062831.3|refseq:NP_787055.1|ensembl:ENST00000359276(transcript)|ensembl:ENST00000380241(transcript)|ensembl:ENST00000443824(transcript)|go:"GO:0003883"(CTP synthase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006220"(pyrimidine nucleotide metabolic process)|go:"GO:0006241"(CTP biosynthetic process)|go:"GO:0006541"(glutamine metabolic process)|go:"GO:0019856"(pyrimidine nucleobase biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0044210"('de novo' CTP biosynthetic process)|go:"GO:0097268"(cytoophidium)|interpro:IPR004468(CTP synthase)|interpro:IPR017456(CTP synthase, N-terminal)|interpro:IPR017926|interpro:IPR027417|interpro:IPR029062|interpro:IPR033828|rcsb pdb:2V4U|rcsb pdb:2VKT|rcsb pdb:3IHL|rcsb pdb:6PK4|rcsb pdb:6PK7|reactome:R-HSA-499943|refseq:XP_006724566.1|refseq:XP_005274619.1	sgd:S000006029|refseq:NP_015217.1|dip:DIP-5256N|ensemblfungi:YPL108W(gene)|ensemblfungi:YPL108W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)	-	-	crc64:65A39A86CDA75D43	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:BU/tvZTUS1d42+j0qSGAg7ND25Y9606	rogid:AzmIxOHHcaAoK/Paeo2aThOM2i8559292	intact-crc:DD9A21A6AFDDB15D|rigid:W3tjJMSZcOCTqlcWwqXtIEyUQy8	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P40956	uniprotkb:Q9NRA8-2	intact:EBI-7968|uniprotkb:D6VTX2|ensemblfungi:YGL181W	intact:EBI-11531709|ensembl:ENSP00000342927	psi-mi:gts1_yeast(display_long)|uniprotkb:YGL181W(locus name)|uniprotkb:GTS1(gene name)|psi-mi:GTS1(display_short)|uniprotkb:LSR1(gene name synonym)|uniprotkb:Protein LSR1(gene name synonym)	psi-mi:q9nra8-2(display_long)|uniprotkb:Eukaryotic translation initiation factor 4E nuclear import factor 1(gene name synonym)|uniprotkb:EIF4ENIF1(gene name)|psi-mi:EIF4ENIF1(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554476|imex:IM-24995-4190	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011334.1|sgd:S000003149|mint:P40956|dip:DIP-2746N|ensemblfungi:YGL181W(gene)|ensemblfungi:YGL181W_mRNA(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0006897"(endocytosis)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010512"(negative regulation of phosphatidylinositol biosynthetic process)|go:"GO:0030479"(actin cortical patch)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR037278|interpro:IPR038508	ensembl:ENSG00000184708(gene)|ensembl:ENST00000344710(transcript)|intact:EBI-301024(isoform-parent)|uniprotkb:Q9NRA8-2(isoform-parent)	-	crc64:D687E3BF6B620795	isoform-comment:No experimental confirmation available.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:8kgpssCRrHiTHsFaOH2nDK6EIjk559292	rogid:VQghhcptYh8k783QTJChpGbP/lU9606	intact-crc:796AE885E8E4B3A2|rigid:WE2+SYyQQcCNUzCbGUz+wCkFZFo	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9NQC3-3	uniprotkb:P38340	intact:EBI-11526335|ensembl:ENSP00000378107	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:q9nqc3-3(display_long)|uniprotkb:Foocen(gene name synonym)|uniprotkb:KIAA0886(gene name synonym)|uniprotkb:NOGO(gene name synonym)|uniprotkb:Neurite outgrowth inhibitor(gene name synonym)|uniprotkb:Neuroendocrine-specific protein(gene name synonym)|uniprotkb:Neuroendocrine-specific protein C homolog(gene name synonym)|uniprotkb:RTN-x(gene name synonym)|uniprotkb:Reticulon-5(gene name synonym)|uniprotkb:My043(orf name)|uniprotkb:SP1507(orf name)|uniprotkb:Foocen-S(isoform synonym)|uniprotkb:Nogo-C(isoform synonym)|uniprotkb:RTN4(gene name)|psi-mi:RTN4(display_short)|uniprotkb:RTN4C(isoform synonym)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554456|imex:IM-24995-4185	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-715945(isoform-parent)|ensembl:ENSG00000115310(gene)|ensembl:ENST00000394609(transcript)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F	-	-	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:Iq/LlFtXjFyIIfxZ1l3NTKURpyA9606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:2AF390FF83DF8EBA|rigid:RPbYVC0UaomGCxRAx3vYWwqIvCQ	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P53286	uniprotkb:Q9NRA8	intact:EBI-3796|uniprotkb:D6VUS2|ensemblfungi:YGR142W	intact:EBI-301024|uniprotkb:B1AKL2|uniprotkb:Q8NCF2|uniprotkb:Q9H708|uniprotkb:B2RBF1|ensembl:ENSP00000328103|ensembl:ENSP00000380659|intact:EBI-877635|uniprotkb:B1AKL3	psi-mi:btn2_yeast(display_long)|uniprotkb:YGR142W(locus name)|uniprotkb:BTN2(gene name)|psi-mi:BTN2(display_short)|uniprotkb:Batten disease protein 2(gene name synonym)	psi-mi:4et_human(display_long)|uniprotkb:EIF4ENIF1(gene name)|psi-mi:EIF4ENIF1(display_short)|uniprotkb:Eukaryotic translation initiation factor 4E nuclear import factor 1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554468|imex:IM-24995-4188	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003374|refseq:NP_011658.3|dip:DIP-5534N|mint:P53286|ensemblfungi:YGR142W(gene)|ensemblfungi:YGR142W_mRNA(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005634"(nucleus)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006865"(amino acid transport)|go:"GO:0006885"(regulation of pH)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051087"(chaperone binding)|go:"GO:0140311"(protein sequestering activity)	ensembl:ENSP00000328103|ensembl:ENST00000344710|ensembl:ENSP00000342927|ensembl:ENSP00000380659|ensembl:ENSG00000184708(gene)|ensembl:ENST00000330125(transcript)|ensembl:ENST00000397525(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0016020"(membrane)|go:"GO:0016605"(PML body)|go:"GO:0016607"(nuclear speck)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019900"(kinase binding)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0033962"(P-body assembly)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0106289"(negative regulation of deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:1905618"(positive regulation of miRNA-mediated gene silencing by inhibition of translation)|interpro:IPR018862|mint:Q9NRA8|rcsb pdb:5ANR|rcsb pdb:6F9W|rcsb pdb:6X2R|refseq:NP_001157973.1|refseq:NP_001157974.1|refseq:NP_062817.2|refseq:XP_011528582.1|refseq:XP_011528583.1|refseq:XP_005261743.1|refseq:XP_005261744.1|refseq:XP_005261745.1|refseq:XP_016884353.1	-	crc64:E7AE1EB1E3612F3E	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Cu27xkwGMNyS4zLvUaG1UeH2mE0559292	rogid:4A9mF81S/ePAraruTNYgovUdkT49606	intact-crc:6077328B6EB32558|rigid:rK4UkiAgNVvsp9+KRrX3rwJzKz4	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P40454	uniprotkb:Q9NR46	intact:EBI-25278|uniprotkb:D6VVD4|ensemblfungi:YIL153W	intact:EBI-749607|uniprotkb:A8MPS4|uniprotkb:Q8WY61|uniprotkb:Q96JH9|uniprotkb:A6NC47|ensembl:ENSP00000361640|ensembl:ENSP00000361645	psi-mi:ptpa1_yeast(display_long)|uniprotkb:YIL153W(locus name)|uniprotkb:RRD1(gene name)|psi-mi:RRD1(display_short)|uniprotkb:NCS1(gene name synonym)|uniprotkb:YPA1(gene name synonym)|uniprotkb:Peptidyl-prolyl cis-trans isomerase PTPA-1(gene name synonym)|uniprotkb:Phosphotyrosyl phosphatase activator 1(gene name synonym)	psi-mi:shlb2_human(display_long)|uniprotkb:SH3 domain-containing GRB2-like protein B2(gene name synonym)|uniprotkb:SH3GLB2(gene name)|psi-mi:SH3GLB2(display_short)|uniprotkb:KIAA1848(gene name synonym)|uniprotkb:PP578(orf name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554464|imex:IM-24995-4187	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012113.1|sgd:S000001415|mint:P40454|dip:DIP-5663N|ensemblfungi:YIL153W(gene)|ensemblfungi:YIL153W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006914"(autophagy)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008160"(protein tyrosine phosphatase activator activity)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0043618"(regulation of transcription from RNA polymerase II promoter in response to stress)|interpro:IPR004327(Phosphotyrosyl phosphatase activator, PTPA)|interpro:IPR037218|interpro:IPR043170|rcsb pdb:2IXO|rcsb pdb:2IXP	refseq:NP_064530.1|refseq:NP_001273974.1|refseq:NP_001273975.1|refseq:XP_005252158.1|ensembl:ENSG00000148341(gene)|ensembl:ENST00000372559(transcript)|ensembl:ENST00000372564(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|interpro:IPR001452(Src homology-3)|interpro:IPR004148(BAR)|interpro:IPR027267|interpro:IPR035640|interpro:IPR036028|mint:Q9NR46	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:It2q8WlpmvLEZ1fqpRF5Fypw9Q4559292	rogid:9C0QF9xLb5A6eYQBK2aU/J1aGVo9606	intact-crc:CF88CC0DD875093D|rigid:HyVSTToe8JVRRQ/VlG5SkOii4/4	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P53296	uniprotkb:Q9NQC3-3	intact:EBI-3165|uniprotkb:E9P955|ensemblfungi:YGR177C|uniprotkb:D6VUW1	intact:EBI-11526335|ensembl:ENSP00000378107	psi-mi:atf2_yeast(display_long)|uniprotkb:ATF2(gene name)|psi-mi:ATF2(display_short)|uniprotkb:"Acetyl-CoA:pregnenolone acetyltransferase"(gene name synonym)|uniprotkb:G7135(orf name)|uniprotkb:YGR177C(locus name)	psi-mi:q9nqc3-3(display_long)|uniprotkb:Foocen(gene name synonym)|uniprotkb:KIAA0886(gene name synonym)|uniprotkb:NOGO(gene name synonym)|uniprotkb:Neurite outgrowth inhibitor(gene name synonym)|uniprotkb:Neuroendocrine-specific protein(gene name synonym)|uniprotkb:Neuroendocrine-specific protein C homolog(gene name synonym)|uniprotkb:RTN-x(gene name synonym)|uniprotkb:Reticulon-5(gene name synonym)|uniprotkb:My043(orf name)|uniprotkb:SP1507(orf name)|uniprotkb:Foocen-S(isoform synonym)|uniprotkb:Nogo-C(isoform synonym)|uniprotkb:RTN4(gene name)|psi-mi:RTN4(display_short)|uniprotkb:RTN4C(isoform synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554460|imex:IM-24995-4186	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011693.1|sgd:S000003409|ensemblfungi:YGR177C(gene)|ensemblfungi:YGR177C_mRNA(transcript)|go:"GO:0004026"(alcohol O-acetyltransferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0008080"(N-acetyltransferase activity)|go:"GO:0008202"(steroid metabolic process)|go:"GO:0009636"(response to toxic substance)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0034209"(sterol acetylation)|go:"GO:1901089"(acetate ester metabolic process involved in fermentation)|interpro:IPR010828(Alcohol acetyltransferase)|dip:DIP-5544N|mint:P53296	intact:EBI-715945(isoform-parent)|ensembl:ENSG00000115310(gene)|ensembl:ENST00000394609(transcript)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:tFI+2rcFXzDfDteDJv8wwBGUh0c559292	rogid:Iq/LlFtXjFyIIfxZ1l3NTKURpyA9606	intact-crc:E2645851CBC34008|rigid:YGDqpIyHMtZotWwLPGQNqshzKi0	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P40956	uniprotkb:Q9NRA8	intact:EBI-7968|uniprotkb:D6VTX2|ensemblfungi:YGL181W	intact:EBI-301024|uniprotkb:B1AKL2|uniprotkb:Q8NCF2|uniprotkb:Q9H708|uniprotkb:B2RBF1|ensembl:ENSP00000328103|ensembl:ENSP00000380659|intact:EBI-877635|uniprotkb:B1AKL3	psi-mi:gts1_yeast(display_long)|uniprotkb:YGL181W(locus name)|uniprotkb:GTS1(gene name)|psi-mi:GTS1(display_short)|uniprotkb:LSR1(gene name synonym)|uniprotkb:Protein LSR1(gene name synonym)	psi-mi:4et_human(display_long)|uniprotkb:EIF4ENIF1(gene name)|psi-mi:EIF4ENIF1(display_short)|uniprotkb:Eukaryotic translation initiation factor 4E nuclear import factor 1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554472|imex:IM-24995-4189	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011334.1|sgd:S000003149|mint:P40956|dip:DIP-2746N|ensemblfungi:YGL181W(gene)|ensemblfungi:YGL181W_mRNA(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0006897"(endocytosis)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010512"(negative regulation of phosphatidylinositol biosynthetic process)|go:"GO:0030479"(actin cortical patch)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR037278|interpro:IPR038508	ensembl:ENSP00000328103|ensembl:ENST00000344710|ensembl:ENSP00000342927|ensembl:ENSP00000380659|ensembl:ENSG00000184708(gene)|ensembl:ENST00000330125(transcript)|ensembl:ENST00000397525(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0016020"(membrane)|go:"GO:0016605"(PML body)|go:"GO:0016607"(nuclear speck)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019900"(kinase binding)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0033962"(P-body assembly)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0106289"(negative regulation of deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:1905618"(positive regulation of miRNA-mediated gene silencing by inhibition of translation)|interpro:IPR018862|mint:Q9NRA8|rcsb pdb:5ANR|rcsb pdb:6F9W|rcsb pdb:6X2R|refseq:NP_001157973.1|refseq:NP_001157974.1|refseq:NP_062817.2|refseq:XP_011528582.1|refseq:XP_011528583.1|refseq:XP_005261743.1|refseq:XP_005261744.1|refseq:XP_005261745.1|refseq:XP_016884353.1	-	crc64:D687E3BF6B620795	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:8kgpssCRrHiTHsFaOH2nDK6EIjk559292	rogid:4A9mF81S/ePAraruTNYgovUdkT49606	intact-crc:5DABA2C33F755433|rigid:M4JgLF5EA5zU5iL3Fn5trsEiHac	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9NS73	uniprotkb:Q06411	intact:EBI-741953|uniprotkb:Q86TZ2|uniprotkb:Q96AS5|uniprotkb:Q9BS93|uniprotkb:Q9NZE1|ensembl:ENSP00000399718	intact:EBI-576|uniprotkb:D6VZ60|ensemblfungi:YLR424W	psi-mi:mbip1_human(display_long)|uniprotkb:MAPK upstream kinase-binding inhibitory protein(gene name synonym)|uniprotkb:MBIP(gene name)|psi-mi:MBIP(display_short)|uniprotkb:BM-015(orf name)	psi-mi:sp382_yeast(display_long)|uniprotkb:NTR1(gene name synonym)|uniprotkb:YLR424W(locus name)|uniprotkb:SPP382(gene name)|psi-mi:SPP382(display_short)|uniprotkb:CCF8(gene name synonym)|uniprotkb:Suppressor of PRP38 protein 2(gene name synonym)|uniprotkb:Nineteen complex-related protein 1(gene name synonym)|uniprotkb:CLF1 complex factor 8(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554508|imex:IM-24995-4198	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001138363.1|refseq:NP_057670.2|ensembl:ENSG00000151332(gene)|ensembl:ENST00000416007(transcript)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0042802"(identical protein binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0046330"(positive regulation of JNK cascade)|interpro:IPR026062|mint:Q9NS73|reactome:R-HSA-3214847|go:"GO:0005654"(nucleoplasm)|refseq:NP_001295039.1	refseq:NP_013528.1|sgd:S000004416|dip:DIP-1491N|mint:Q06411|ensemblfungi:YLR424W(gene)|ensemblfungi:YLR424W_mRNA(transcript)|go:"GO:0000349"(generation of catalytic spliceosome for first transesterification step)|go:"GO:0000390"(spliceosomal complex disassembly)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0071008"(U2-type post-mRNA release spliceosomal complex)|go:"GO:1904876"(negative regulation of DNA ligase activity)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR000467(D111/G-patch)|rcsb pdb:5Y88	-	-	crc64:9986B547B9582338	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:PjaEuab6wwOyGImpNYFZfQ+TUvU9606	rogid:HrG54vTE2zs7jxPSzi+9eeA23/k559292	intact-crc:0B1FBEEE6E1BB7EA|rigid:8UFlC1frtUrvlYzYlmHIuHNhawM	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P38340	uniprotkb:Q9NRY6	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-750734|uniprotkb:Q567U0|uniprotkb:Q8NBW6|uniprotkb:Q96F13|uniprotkb:A8K252|ensembl:ENSP00000316021|ensembl:ENSP00000459019|ensembl:ENSP00000459419|ensembl:ENSP00000491350|ensembl:ENSP00000491393|ensembl:ENSP00000492026|ensembl:ENSP00000492083|ensembl:ENSP00000483743	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:pls3_human(display_long)|uniprotkb:"Ca(2+)-dependent phospholipid scramblase 3"(gene name synonym)|uniprotkb:PLSCR3(gene name)|psi-mi:PLSCR3(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554504|imex:IM-24995-4197	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F	refseq:NP_001188505.1|refseq:NP_065093.2|ensembl:ENSG00000187838(gene)|ensembl:ENSG00000284009(gene)|ensembl:ENST00000324822(transcript)|ensembl:ENST00000574401(transcript)|ensembl:ENST00000576201(transcript)|ensembl:ENST00000619711(transcript)|ensembl:ENST00000639780(transcript)|ensembl:ENST00000639874(transcript)|ensembl:ENST00000640053(transcript)|ensembl:ENST00000640375(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017121"(plasma membrane phospholipid scrambling)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0017128"(phospholipid scramblase activity)|go:"GO:0032049"(cardiolipin biosynthetic process)|go:"GO:0032791"(lead ion binding)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043621"(protein self-association)|go:"GO:0045340"(mercury ion binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0090199"(regulation of release of cytochrome c from mitochondria)|interpro:IPR005552(Scramblase)	-	crc64:66699F37B0013088	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:JKzacFCwrCQpcI3EJsLvpAbLFCA9606	intact-crc:B2CB77425375CC7C|rigid:kYHWB6acjNUbKK6TPDe1djT2Fc0	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P53829	uniprotkb:Q9NRG1	intact:EBI-28306|uniprotkb:D6W0Q5|ensemblfungi:YNL288W	intact:EBI-739759|uniprotkb:Q53HA7|uniprotkb:Q59EL9|uniprotkb:Q5VV18|uniprotkb:Q5VV20|uniprotkb:B7Z1Z3|ensembl:ENSP00000318602	psi-mi:caf40_yeast(display_long)|uniprotkb:YNL288W(locus name)|uniprotkb:N0540(orf name)|uniprotkb:40 kDa CCR4-associated factor(gene name synonym)|uniprotkb:CAF40(gene name)|psi-mi:CAF40(display_short)	psi-mi:prdc1_human(display_long)|uniprotkb:PRTFDC1(gene name)|psi-mi:PRTFDC1(display_short)|uniprotkb:HHGP(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554488|imex:IM-24995-4193	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014111.1|sgd:S000005232|dip:DIP-1995N|mint:P53829|ensemblfungi:YNL288W(gene)|ensemblfungi:YNL288W_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR007216(Cell differentiation, Rcd1-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:4CV5	refseq:NP_001269715.1|refseq:NP_064585.1|ensembl:ENSG00000099256(gene)|ensembl:ENST00000320152(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0006166"(purine ribonucleoside salvage)|go:"GO:0042803"(protein homodimerization activity)|interpro:IPR000836(Phosphoribosyltransferase)|interpro:IPR005904(Hypoxanthine phosphoribosyl transferase)|interpro:IPR029057|rcsb pdb:2JBH	-	crc64:F3DBABE6AD3C7F3C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:etuSSgFGQOcgxPDexEXUqQg6H5s559292	rogid:grTZnSalFILRSeeZBjM1mTtF0xo9606	intact-crc:8B18700BBBB088CA|rigid:djKy/pJTqauRfpWeChUlWsatnr4	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P38128	uniprotkb:Q9NRQ2	intact:EBI-17469|uniprotkb:D6VQH6|ensemblfungi:YBR182C	intact:EBI-769257|uniprotkb:Q2TTR3|uniprotkb:Q658L3|uniprotkb:Q7Z505|uniprotkb:A8K2E9|uniprotkb:Q6ZR73|ensembl:ENSP00000347038|ensembl:ENSP00000399315|ensembl:ENSP00000419040	psi-mi:smp1_yeast(display_long)|uniprotkb:YBR1245(orf name)|uniprotkb:YBR182C(locus name)|uniprotkb:SMP1(gene name)|psi-mi:SMP1(display_short)	psi-mi:pls4_human(display_long)|uniprotkb:"Ca(2+)-dependent phospholipid scramblase 4"(gene name synonym)|uniprotkb:TRA1(gene name synonym)|uniprotkb:Cell growth-inhibiting gene 43 protein(gene name synonym)|uniprotkb:PLSCR4(gene name)|psi-mi:PLSCR4(display_short)|uniprotkb:GIG43(orf name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554496|imex:IM-24995-4195	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009741.3|sgd:S000000386|interpro:IPR002100(Transcription factor, MADS-box)|ensemblfungi:YBR182C(gene)|ensemblfungi:YBR182C_mRNA(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|reactome:R-SCE-525793|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR033896|interpro:IPR036879	refseq:XP_005247711.1|refseq:XP_005247712.1|refseq:NP_001121778.1|refseq:NP_001170775.1|refseq:NP_065086.2|refseq:NP_001121776.1|refseq:NP_001121777.1|refseq:XP_011511333.1|ensembl:ENSP00000347038|ensembl:ENST00000433593|ensembl:ENSP00000415605|ensembl:ENSP00000399315|ensembl:ENSP00000419040|ensembl:ENSG00000114698(gene)|ensembl:ENST00000354952(transcript)|ensembl:ENST00000446574(transcript)|ensembl:ENST00000493382(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017121"(plasma membrane phospholipid scrambling)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0017128"(phospholipid scramblase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0071222"(cellular response to lipopolysaccharide)|interpro:IPR005552(Scramblase)|rcsb pdb:3Q5U	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:+iBP5NzZkrXnslYfo1RDMrlTAIQ559292	rogid:bqEhBoGZZebMZn4JWpg/X0qU49A9606	intact-crc:9BDB351CB01B7E95|rigid:dnwTh4HBKpMmYhau8jiYq073Chc	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9NRG1	uniprotkb:P15202	intact:EBI-739759|uniprotkb:Q53HA7|uniprotkb:Q59EL9|uniprotkb:Q5VV18|uniprotkb:Q5VV20|uniprotkb:B7Z1Z3|ensembl:ENSP00000318602	intact:EBI-4061|uniprotkb:E9P947|uniprotkb:D6VSN6|ensemblfungi:YDR256C	psi-mi:prdc1_human(display_long)|uniprotkb:PRTFDC1(gene name)|psi-mi:PRTFDC1(display_short)|uniprotkb:HHGP(gene name synonym)	psi-mi:cata_yeast(display_long)|uniprotkb:YD9320A.06C(orf name)|uniprotkb:YDR256C(locus name)|uniprotkb:CTA1(gene name)|psi-mi:CTA1(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554492|imex:IM-24995-4194	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001269715.1|refseq:NP_064585.1|ensembl:ENSG00000099256(gene)|ensembl:ENST00000320152(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0006166"(purine ribonucleoside salvage)|go:"GO:0042803"(protein homodimerization activity)|interpro:IPR000836(Phosphoribosyltransferase)|interpro:IPR005904(Hypoxanthine phosphoribosyl transferase)|interpro:IPR029057|rcsb pdb:2JBH	sgd:S000002664|refseq:NP_010542.1|dip:DIP-4320N|mint:P15202|ensemblfungi:YDR256C(gene)|ensemblfungi:YDR256C_mRNA(transcript)|go:"GO:0000302"(response to reactive oxygen species)|go:"GO:0001315"(age-dependent response to reactive oxygen species)|go:"GO:0004096"(catalase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005777"(peroxisome)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0020037"(heme binding)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0046872"(metal ion binding)|interpro:IPR002226(Catalase)|interpro:IPR010582(Catalase-related)|interpro:IPR011614(Catalase, N-terminal)|interpro:IPR018028|interpro:IPR020835|interpro:IPR024708|interpro:IPR024711|rcsb pdb:1A4E	-	-	crc64:22DFCC599D79801F	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:grTZnSalFILRSeeZBjM1mTtF0xo9606	rogid:+NMosmB3jzYGleF7X88sJ2qLm/Y559292	intact-crc:4B7ED639CB3B3C01|rigid:9q7gYQNJc5B+h4/yED4XUFOSjUs	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P32502	uniprotkb:Q9NRY6	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	intact:EBI-750734|uniprotkb:Q567U0|uniprotkb:Q8NBW6|uniprotkb:Q96F13|uniprotkb:A8K252|ensembl:ENSP00000316021|ensembl:ENSP00000459019|ensembl:ENSP00000459419|ensembl:ENSP00000491350|ensembl:ENSP00000491393|ensembl:ENSP00000492026|ensembl:ENSP00000492083|ensembl:ENSP00000483743	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:pls3_human(display_long)|uniprotkb:"Ca(2+)-dependent phospholipid scramblase 3"(gene name synonym)|uniprotkb:PLSCR3(gene name)|psi-mi:PLSCR3(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554500|imex:IM-24995-4196	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731	refseq:NP_001188505.1|refseq:NP_065093.2|ensembl:ENSG00000187838(gene)|ensembl:ENSG00000284009(gene)|ensembl:ENST00000324822(transcript)|ensembl:ENST00000574401(transcript)|ensembl:ENST00000576201(transcript)|ensembl:ENST00000619711(transcript)|ensembl:ENST00000639780(transcript)|ensembl:ENST00000639874(transcript)|ensembl:ENST00000640053(transcript)|ensembl:ENST00000640375(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017121"(plasma membrane phospholipid scrambling)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0017128"(phospholipid scramblase activity)|go:"GO:0032049"(cardiolipin biosynthetic process)|go:"GO:0032791"(lead ion binding)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043621"(protein self-association)|go:"GO:0045340"(mercury ion binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0090199"(regulation of release of cytochrome c from mitochondria)|interpro:IPR005552(Scramblase)	-	crc64:A5409FAF1594854C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	rogid:JKzacFCwrCQpcI3EJsLvpAbLFCA9606	intact-crc:7096FEB691AC2CC2|rigid:J7CqgW3akkZCt3ZZ9/kD37ajjBI	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q06411	uniprotkb:Q9NS73-5	intact:EBI-576|uniprotkb:D6VZ60|ensemblfungi:YLR424W	intact:EBI-10182361|ensembl:ENSP00000324444	psi-mi:sp382_yeast(display_long)|uniprotkb:NTR1(gene name synonym)|uniprotkb:YLR424W(locus name)|uniprotkb:SPP382(gene name)|psi-mi:SPP382(display_short)|uniprotkb:CCF8(gene name synonym)|uniprotkb:Suppressor of PRP38 protein 2(gene name synonym)|uniprotkb:Nineteen complex-related protein 1(gene name synonym)|uniprotkb:CLF1 complex factor 8(gene name synonym)	psi-mi:q9ns73-5(display_long)|uniprotkb:MAPK upstream kinase-binding inhibitory protein(gene name synonym)|uniprotkb:BM-015(orf name)|uniprotkb:MBIP(gene name)|psi-mi:MBIP(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554516|imex:IM-24995-4200	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013528.1|sgd:S000004416|dip:DIP-1491N|mint:Q06411|ensemblfungi:YLR424W(gene)|ensemblfungi:YLR424W_mRNA(transcript)|go:"GO:0000349"(generation of catalytic spliceosome for first transesterification step)|go:"GO:0000390"(spliceosomal complex disassembly)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0071008"(U2-type post-mRNA release spliceosomal complex)|go:"GO:1904876"(negative regulation of DNA ligase activity)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR000467(D111/G-patch)|rcsb pdb:5Y88	ensembl:ENSG00000151332(gene)|ensembl:ENST00000318473(transcript)|intact:EBI-741953(isoform-parent)|uniprotkb:Q9NS73-5(isoform-parent)	-	crc64:9986B547B9582338	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:HrG54vTE2zs7jxPSzi+9eeA23/k559292	rogid:JVmcJrT3SXRZwv9U285cNqnXWQE9606	intact-crc:634DCBBEFF63F9F2|rigid:jFJGl0qhOY6Tud0wyHcxNT3P9XU	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q02821	uniprotkb:Q9NS73	intact:EBI-1797|uniprotkb:D6W0Z8|ensemblfungi:YNL189W	intact:EBI-741953|uniprotkb:Q86TZ2|uniprotkb:Q96AS5|uniprotkb:Q9BS93|uniprotkb:Q9NZE1|ensembl:ENSP00000399718	psi-mi:ima1_yeast(display_long)|uniprotkb:SRP1(gene name)|psi-mi:SRP1(display_short)|uniprotkb:KAP60(gene name synonym)|uniprotkb:YNL189W(locus name)|uniprotkb:N1606(orf name)|uniprotkb:Karyopherin subunit alpha(gene name synonym)|uniprotkb:Karyopherin-60(gene name synonym)|uniprotkb:Serine-rich RNA polymerase I suppressor protein(gene name synonym)	psi-mi:mbip1_human(display_long)|uniprotkb:MAPK upstream kinase-binding inhibitory protein(gene name synonym)|uniprotkb:MBIP(gene name)|psi-mi:MBIP(display_short)|uniprotkb:BM-015(orf name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554512|imex:IM-24995-4199	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014210.1|sgd:S000005133|dip:DIP-728N|mint:Q02821|ensemblfungi:YNL189W(gene)|ensemblfungi:YNL189W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0031144"(proteasome localization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042564"(NLS-dependent protein nuclear import complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|rcsb pdb:1BK5|rcsb pdb:1BK6|rcsb pdb:1EE4|rcsb pdb:1EE5|rcsb pdb:1UN0|rcsb pdb:1WA5|rcsb pdb:2C1T|rcsb pdb:4PVZ|rcsb pdb:4XZR|rcsb pdb:5H2W|rcsb pdb:5H2X|rcsb pdb:5T94	refseq:NP_001138363.1|refseq:NP_057670.2|ensembl:ENSG00000151332(gene)|ensembl:ENST00000416007(transcript)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0042802"(identical protein binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0046330"(positive regulation of JNK cascade)|interpro:IPR026062|mint:Q9NS73|reactome:R-HSA-3214847|go:"GO:0005654"(nucleoplasm)|refseq:NP_001295039.1	-	crc64:8D3A0CB76F2E7C00	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:NyzC93xnBCb8DX/AH346lwg4u2A559292	rogid:PjaEuab6wwOyGImpNYFZfQ+TUvU9606	intact-crc:5442B40CCCBBBCDE|rigid:QDAkj1JjcjC1M6fXPGwGjxHqPWE	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P32571	uniprotkb:Q9NSC5	intact:EBI-19840|uniprotkb:D6VS55|ensemblfungi:YDR069C	intact:EBI-748420|uniprotkb:O14580|uniprotkb:O95350|uniprotkb:Q9NSB9|uniprotkb:Q9NSC0|intact:EBI-2557809|uniprotkb:E9PCW9|uniprotkb:Q9NSC1|intact:EBI-28972925|ensembl:ENSP00000376162|ensembl:ENSP00000439937|ensembl:ENSP00000446026|intact:EBI-10175777|uniprotkb:B2RA10	psi-mi:ubp4_yeast(display_long)|uniprotkb:DOA4(gene name)|psi-mi:DOA4(display_short)|uniprotkb:MUT4(gene name synonym)|uniprotkb:SSV7(gene name synonym)|uniprotkb:YDR069C(locus name)|uniprotkb:YD9609.23C(orf name)|uniprotkb:YD8554.02C(orf name)|uniprotkb:D4270(orf name)|uniprotkb:NPI2(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 4(gene name synonym)|uniprotkb:Deubiquitinating enzyme 4(gene name synonym)|uniprotkb:Vacuole biogenesis protein SSV7(gene name synonym)|uniprotkb:Ubiquitin thioesterase 4(gene name synonym)|uniprotkb:DOS1(gene name synonym)|uniprotkb:UBP4(gene name synonym)	psi-mi:home3_human(display_long)|uniprotkb:HOMER3(gene name)|psi-mi:HOMER3(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554536|imex:IM-24995-4205	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002476|ensemblfungi:YDR069C(gene)|ensemblfungi:YDR069C_mRNA(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005739"(mitochondrion)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0010992"(ubiquitin recycling)|go:"GO:0010995"(free ubiquitin chain depolymerization)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0031902"(late endosome membrane)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0070676"(intralumenal vesicle formation)|go:"GO:1904669"(ATP export)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR001763(Rhodanese-like)|interpro:IPR018200|interpro:IPR028889|interpro:IPR036873|interpro:IPR038765|refseq:NP_010354.3|dip:DIP-5298N|mint:P32571	ensembl:ENST00000221222|ensembl:ENSP00000221222|ensembl:ENSP00000376162|ensembl:ENST00000433218|ensembl:ENSP00000396154|ensembl:ENSP00000439937|ensembl:ENSP00000446026|ensembl:ENST00000594439|ensembl:ENSP00000471835|refseq:XP_006723006.1|refseq:XP_006723007.1|refseq:NP_001139193.1|refseq:NP_001139194.1|refseq:NP_004829.3|refseq:NP_001139196.1|ensembl:ENSG00000051128(gene)|ensembl:ENST00000392351(transcript)|ensembl:ENST00000539827(transcript)|ensembl:ENST00000542541(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006605"(protein targeting)|go:"GO:0007216"(G protein-coupled glutamate receptor signaling pathway)|go:"GO:0014069"(postsynaptic density)|go:"GO:0030425"(dendrite)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0035256"(G protein-coupled glutamate receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|go:"GO:2001256"(regulation of store-operated calcium entry)|interpro:IPR000697(EVH1)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR044100|mint:Q9NSC5|rcsb pdb:2P8V|rcsb pdb:3CVF|reactome:R-HSA-6794361	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:UTBSWmpygyxo1ygxp/sQ8wgqnMo559292	rogid:U1y/y52nnf7zQUCNQlqk7JDgXi49606	intact-crc:5A86BD8C847447D0|rigid:9DyDDr3Gmjn5La0X0Ir9/eLyM+c	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9NS73-5	uniprotkb:Q02821	intact:EBI-10182361|ensembl:ENSP00000324444	intact:EBI-1797|uniprotkb:D6W0Z8|ensemblfungi:YNL189W	psi-mi:q9ns73-5(display_long)|uniprotkb:MAPK upstream kinase-binding inhibitory protein(gene name synonym)|uniprotkb:BM-015(orf name)|uniprotkb:MBIP(gene name)|psi-mi:MBIP(display_short)	psi-mi:ima1_yeast(display_long)|uniprotkb:SRP1(gene name)|psi-mi:SRP1(display_short)|uniprotkb:KAP60(gene name synonym)|uniprotkb:YNL189W(locus name)|uniprotkb:N1606(orf name)|uniprotkb:Karyopherin subunit alpha(gene name synonym)|uniprotkb:Karyopherin-60(gene name synonym)|uniprotkb:Serine-rich RNA polymerase I suppressor protein(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554520|imex:IM-24995-4201	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000151332(gene)|ensembl:ENST00000318473(transcript)|intact:EBI-741953(isoform-parent)|uniprotkb:Q9NS73-5(isoform-parent)	refseq:NP_014210.1|sgd:S000005133|dip:DIP-728N|mint:Q02821|ensemblfungi:YNL189W(gene)|ensemblfungi:YNL189W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0031144"(proteasome localization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042564"(NLS-dependent protein nuclear import complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|rcsb pdb:1BK5|rcsb pdb:1BK6|rcsb pdb:1EE4|rcsb pdb:1EE5|rcsb pdb:1UN0|rcsb pdb:1WA5|rcsb pdb:2C1T|rcsb pdb:4PVZ|rcsb pdb:4XZR|rcsb pdb:5H2W|rcsb pdb:5H2X|rcsb pdb:5T94	-	-	crc64:8D3A0CB76F2E7C00	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:JVmcJrT3SXRZwv9U285cNqnXWQE9606	rogid:NyzC93xnBCb8DX/AH346lwg4u2A559292	intact-crc:6CD37C76D6D9E439|rigid:keYNqWVWUF9B+O6/G0K2ascnBwA	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P38340	uniprotkb:Q9NSC5	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-748420|uniprotkb:O14580|uniprotkb:O95350|uniprotkb:Q9NSB9|uniprotkb:Q9NSC0|intact:EBI-2557809|uniprotkb:E9PCW9|uniprotkb:Q9NSC1|intact:EBI-28972925|ensembl:ENSP00000376162|ensembl:ENSP00000439937|ensembl:ENSP00000446026|intact:EBI-10175777|uniprotkb:B2RA10	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:home3_human(display_long)|uniprotkb:HOMER3(gene name)|psi-mi:HOMER3(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554528|imex:IM-24995-4203	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F	ensembl:ENST00000221222|ensembl:ENSP00000221222|ensembl:ENSP00000376162|ensembl:ENST00000433218|ensembl:ENSP00000396154|ensembl:ENSP00000439937|ensembl:ENSP00000446026|ensembl:ENST00000594439|ensembl:ENSP00000471835|refseq:XP_006723006.1|refseq:XP_006723007.1|refseq:NP_001139193.1|refseq:NP_001139194.1|refseq:NP_004829.3|refseq:NP_001139196.1|ensembl:ENSG00000051128(gene)|ensembl:ENST00000392351(transcript)|ensembl:ENST00000539827(transcript)|ensembl:ENST00000542541(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006605"(protein targeting)|go:"GO:0007216"(G protein-coupled glutamate receptor signaling pathway)|go:"GO:0014069"(postsynaptic density)|go:"GO:0030425"(dendrite)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0035256"(G protein-coupled glutamate receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|go:"GO:2001256"(regulation of store-operated calcium entry)|interpro:IPR000697(EVH1)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR044100|mint:Q9NSC5|rcsb pdb:2P8V|rcsb pdb:3CVF|reactome:R-HSA-6794361	-	crc64:66699F37B0013088	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:U1y/y52nnf7zQUCNQlqk7JDgXi49606	intact-crc:0EDDC5C7A7055C5F|rigid:MadKq7FrrRQ7KphkPSb9mHcWQFQ	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9NSC5	uniprotkb:P40302	intact:EBI-748420|uniprotkb:O14580|uniprotkb:O95350|uniprotkb:Q9NSB9|uniprotkb:Q9NSC0|intact:EBI-2557809|uniprotkb:E9PCW9|uniprotkb:Q9NSC1|intact:EBI-28972925|ensembl:ENSP00000376162|ensembl:ENSP00000439937|ensembl:ENSP00000446026|intact:EBI-10175777|uniprotkb:B2RA10	intact:EBI-13955|ensemblfungi:YMR314W|uniprotkb:D6W0E1	psi-mi:home3_human(display_long)|uniprotkb:HOMER3(gene name)|psi-mi:HOMER3(display_short)	psi-mi:psa6_yeast(display_long)|uniprotkb:PRE5(gene name)|psi-mi:PRE5(display_short)|uniprotkb:YMR314W(locus name)|uniprotkb:YM9924.06(orf name)|uniprotkb:Proteasome component PRE5(gene name synonym)|uniprotkb:Macropain subunit PRE5(gene name synonym)|uniprotkb:Proteinase YSCE subunit PRE5(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit PRE5(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554524|imex:IM-24995-4202	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000221222|ensembl:ENSP00000221222|ensembl:ENSP00000376162|ensembl:ENST00000433218|ensembl:ENSP00000396154|ensembl:ENSP00000439937|ensembl:ENSP00000446026|ensembl:ENST00000594439|ensembl:ENSP00000471835|refseq:XP_006723006.1|refseq:XP_006723007.1|refseq:NP_001139193.1|refseq:NP_001139194.1|refseq:NP_004829.3|refseq:NP_001139196.1|ensembl:ENSG00000051128(gene)|ensembl:ENST00000392351(transcript)|ensembl:ENST00000539827(transcript)|ensembl:ENST00000542541(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006605"(protein targeting)|go:"GO:0007216"(G protein-coupled glutamate receptor signaling pathway)|go:"GO:0014069"(postsynaptic density)|go:"GO:0030425"(dendrite)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0035256"(G protein-coupled glutamate receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|go:"GO:2001256"(regulation of store-operated calcium entry)|interpro:IPR000697(EVH1)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR044100|mint:Q9NSC5|rcsb pdb:2P8V|rcsb pdb:3CVF|reactome:R-HSA-6794361	rcsb pdb:4Y8T|rcsb pdb:4Y8U|rcsb pdb:4Y9Y|rcsb pdb:4Y9Z|rcsb pdb:4YA0|rcsb pdb:4YA1|rcsb pdb:4YA2|rcsb pdb:4YA3|rcsb pdb:4YA4|rcsb pdb:4YA5|rcsb pdb:4Y7X|rcsb pdb:4Y7Y|rcsb pdb:4Y80|rcsb pdb:4Y81|rcsb pdb:4Y82|rcsb pdb:4Y84|rcsb pdb:4Y8G|rcsb pdb:4Y8H|rcsb pdb:4Y8I|rcsb pdb:4Y8J|rcsb pdb:4Y8K|rcsb pdb:4Y8L|rcsb pdb:4Y8M|rcsb pdb:4Y8N|rcsb pdb:4Y8O|rcsb pdb:4Y8P|rcsb pdb:4Y8Q|rcsb pdb:4Y8R|rcsb pdb:4Y8S|rcsb pdb:5FG7|rcsb pdb:5FG9|rcsb pdb:5FGA|rcsb pdb:4YA7|rcsb pdb:4YA9|rcsb pdb:4Z1L|rcsb pdb:5A5B|rcsb pdb:5AHJ|rcsb pdb:5BOU|rcsb pdb:5BXL|rcsb pdb:5BXN|rcsb pdb:5CGF|rcsb pdb:5CGG|rcsb pdb:5CGH|rcsb pdb:5CGI|rcsb pdb:5CZ4|rcsb pdb:5CZ5|rcsb pdb:5CZ6|rcsb pdb:5CZ7|rcsb pdb:5CZ8|rcsb pdb:5CZ9|rcsb pdb:5CZA|rcsb pdb:5D0S|rcsb pdb:5D0T|rcsb pdb:5D0V|rcsb pdb:5D0W|rcsb pdb:5D0X|rcsb pdb:5D0Z|rcsb pdb:5DKI|rcsb pdb:5DKJ|rcsb pdb:5FGD|rcsb pdb:3HYE|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:3MG0|rcsb pdb:3MG4|rcsb pdb:3MG6|rcsb pdb:3MG7|rcsb pdb:3MG8|rcsb pdb:3NZJ|rcsb pdb:3NZW|rcsb pdb:3NZX|rcsb pdb:3OEU|rcsb pdb:3OEV|rcsb pdb:3OKJ|rcsb pdb:3SDI|rcsb pdb:3SDK|rcsb pdb:3SHJ|rcsb pdb:3TDD|rcsb pdb:3UN4|rcsb pdb:3UN8|rcsb pdb:3WXR|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:4EU2|rcsb pdb:4FZC|rcsb pdb:4FZG|rcsb pdb:4G4S|rcsb pdb:4GK7|rcsb pdb:4HNP|rcsb pdb:4HRC|rcsb pdb:4HRD|rcsb pdb:4INR|rcsb pdb:4INT|rcsb pdb:4INU|rcsb pdb:4J70|rcsb pdb:4JSQ|rcsb pdb:4JSU|rcsb pdb:4JT0|rcsb pdb:4LQI|rcsb pdb:4LTC|rcsb pdb:4NNN|rcsb pdb:4NNW|rcsb pdb:4NO1|rcsb pdb:4NO6|rcsb pdb:4NO8|rcsb pdb:4NO9|rcsb pdb:5FGE|rcsb pdb:5FGF|rcsb pdb:5FGG|rcsb pdb:5FGH|rcsb pdb:5FGI|rcsb pdb:5FHS|rcsb pdb:5JHR|rcsb pdb:5JHS|rcsb pdb:5L52|rcsb pdb:5L54|rcsb pdb:5L55|rcsb pdb:5L5A|rcsb pdb:5L5B|rcsb pdb:5L5D|rcsb pdb:5L5E|rcsb pdb:5L5F|rcsb pdb:5L5H|rcsb pdb:5L5I|rcsb pdb:5L5J|rcsb pdb:5L5O|rcsb pdb:5L5P|rcsb pdb:5L5Q|rcsb pdb:5L5R|rcsb pdb:4Q1S|rcsb pdb:4QBY|rcsb pdb:4QLQ|rcsb pdb:4QLS|rcsb pdb:4QLT|rcsb pdb:4QLU|rcsb pdb:4QLV|rcsb pdb:4QUX|rcsb pdb:4QUY|rcsb pdb:4QV0|rcsb pdb:4QV1|rcsb pdb:4QV3|rcsb pdb:4QV4|rcsb pdb:4QV5|rcsb pdb:4QV6|rcsb pdb:4QV7|rcsb pdb:4QV8|rcsb pdb:4QV9|rcsb pdb:4QVL|ensemblfungi:YMR314W(gene)|ensemblfungi:YMR314W_mRNA(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0042175"(nuclear outer membrane-endoplasmic reticulum membrane network)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR035144|rcsb pdb:1FNT|rcsb pdb:1G0U|rcsb pdb:1G65|rcsb pdb:1JD2|rcsb pdb:1RYP|rcsb pdb:1Z7Q|rcsb pdb:2F16|rcsb pdb:2FAK|rcsb pdb:2GPL|rcsb pdb:2ZCY|rcsb pdb:3BDM|rcsb pdb:3D29|rcsb pdb:3DY3|rcsb pdb:3DY4|rcsb pdb:3E47|rcsb pdb:3GPJ|rcsb pdb:3GPT|rcsb pdb:3GPW|rcsb pdb:4QVM|rcsb pdb:4QVN|rcsb pdb:4QVP|rcsb pdb:4QVQ|rcsb pdb:4QVV|rcsb pdb:4QVW|rcsb pdb:4QVY|rcsb pdb:4QW0|rcsb pdb:4QW1|rcsb pdb:4QW3|rcsb pdb:4QW4|rcsb pdb:4QW5|rcsb pdb:4QW6|rcsb pdb:4QW7|rcsb pdb:4QWF|rcsb pdb:4QWG|rcsb pdb:4QWI|rcsb pdb:4QWJ|rcsb pdb:4QWK|rcsb pdb:4QWL|rcsb pdb:4QWR|rcsb pdb:4QWS|rcsb pdb:4QWU|rcsb pdb:4QWX|rcsb pdb:4QXJ|rcsb pdb:4QZ0|rcsb pdb:4QZ1|rcsb pdb:4QZ2|rcsb pdb:4QZ3|rcsb pdb:4QZ4|rcsb pdb:4QZ5|rcsb pdb:4QZ6|rcsb pdb:4QZ7|rcsb pdb:4QZW|rcsb pdb:4QZX|rcsb pdb:4QZZ|rcsb pdb:4R00|rcsb pdb:4R02|rcsb pdb:4R17|rcsb pdb:4R18|rcsb pdb:4RUR|rcsb pdb:4V7O|rcsb pdb:4X6Z|rcsb pdb:4Y69|rcsb pdb:4Y6A|rcsb pdb:4Y6V|rcsb pdb:4Y6Z|rcsb pdb:4Y70|rcsb pdb:4Y74|rcsb pdb:4Y75|rcsb pdb:4Y77|rcsb pdb:4Y78|rcsb pdb:4Y7W|rcsb pdb:5LTT|rcsb pdb:5M2B|rcsb pdb:5MP9|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5NIF|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6G7F|rcsb pdb:6G8M|rcsb pdb:6G8N|rcsb pdb:6GOP|rcsb pdb:6H39|rcsb pdb:6HTB|rcsb pdb:6HTC|rcsb pdb:6HTD|rcsb pdb:6HTP|rcsb pdb:6HTR|rcsb pdb:6HUB|rcsb pdb:6HUC|rcsb pdb:6HUQ|rcsb pdb:6HUU|rcsb pdb:6HUV|rcsb pdb:6HV3|rcsb pdb:6HV4|rcsb pdb:6HV5|rcsb pdb:6HV7|rcsb pdb:6HVA|rcsb pdb:6HVR|rcsb pdb:6HVS|rcsb pdb:6HVT|rcsb pdb:6HVU|rcsb pdb:6HVV|rcsb pdb:5L5S|rcsb pdb:5L5T|rcsb pdb:5L5U|rcsb pdb:5L5V|rcsb pdb:5L5W|rcsb pdb:5L5X|rcsb pdb:5L5Y|rcsb pdb:5L5Z|rcsb pdb:5L60|rcsb pdb:5L61|rcsb pdb:5L62|rcsb pdb:5L63|rcsb pdb:5L64|rcsb pdb:5L65|rcsb pdb:5L66|rcsb pdb:5L67|rcsb pdb:5L68|rcsb pdb:5L69|rcsb pdb:5L6A|rcsb pdb:5L6B|rcsb pdb:5L6C|rcsb pdb:5LAI|rcsb pdb:5LAJ|rcsb pdb:6HVW|rcsb pdb:6HVX|rcsb pdb:6HVY|rcsb pdb:6HW0|rcsb pdb:6HW3|rcsb pdb:6HW4|rcsb pdb:6HW5|rcsb pdb:6HW6|rcsb pdb:6HW7|rcsb pdb:6HW8|rcsb pdb:6HW9|rcsb pdb:6HWA|rcsb pdb:6HWB|rcsb pdb:6HWC|rcsb pdb:6HWD|rcsb pdb:6HWE|rcsb pdb:6HWF|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2X|rcsb pdb:6J30|rcsb pdb:6ZOU|rcsb pdb:6ZP6|rcsb pdb:6ZP8|rcsb pdb:7LS5|rcsb pdb:7LS6|rcsb pdb:7LSX|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|rcsb pdb:6J2Q|refseq:NP_014045.1|sgd:S000004931|mint:P40302|dip:DIP-1528N	-	-	crc64:C43CBCC1C6B9E39E	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:U1y/y52nnf7zQUCNQlqk7JDgXi49606	rogid:C9GPb0JAklkBz0t/YYqRMNEiQss559292	intact-crc:DC84C981F8C6BF99|rigid:xJu4udRnt8uJIyFOJNW18Br9+yU	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9NSC5	uniprotkb:P17157	intact:EBI-748420|uniprotkb:O14580|uniprotkb:O95350|uniprotkb:Q9NSB9|uniprotkb:Q9NSC0|intact:EBI-2557809|uniprotkb:E9PCW9|uniprotkb:Q9NSC1|intact:EBI-28972925|ensembl:ENSP00000376162|ensembl:ENSP00000439937|ensembl:ENSP00000446026|intact:EBI-10175777|uniprotkb:B2RA10	intact:EBI-13327|uniprotkb:Q03089|uniprotkb:Q06888|ensemblfungi:YPL031C|uniprotkb:D6W3Y2	psi-mi:home3_human(display_long)|uniprotkb:HOMER3(gene name)|psi-mi:HOMER3(display_short)	psi-mi:pho85_yeast(display_long)|uniprotkb:PHO85(gene name)|psi-mi:PHO85(display_short)|uniprotkb:SSG3(gene name synonym)|uniprotkb:P7102.18A(orf name)|uniprotkb:Serine/threonine-protein kinase PHO85(gene name synonym)|uniprotkb:Negative regulator of the PHO system(gene name synonym)|uniprotkb:YPL031C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554532|imex:IM-24995-4204	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000221222|ensembl:ENSP00000221222|ensembl:ENSP00000376162|ensembl:ENST00000433218|ensembl:ENSP00000396154|ensembl:ENSP00000439937|ensembl:ENSP00000446026|ensembl:ENST00000594439|ensembl:ENSP00000471835|refseq:XP_006723006.1|refseq:XP_006723007.1|refseq:NP_001139193.1|refseq:NP_001139194.1|refseq:NP_004829.3|refseq:NP_001139196.1|ensembl:ENSG00000051128(gene)|ensembl:ENST00000392351(transcript)|ensembl:ENST00000539827(transcript)|ensembl:ENST00000542541(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006605"(protein targeting)|go:"GO:0007216"(G protein-coupled glutamate receptor signaling pathway)|go:"GO:0014069"(postsynaptic density)|go:"GO:0030425"(dendrite)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0035256"(G protein-coupled glutamate receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|go:"GO:2001256"(regulation of store-operated calcium entry)|interpro:IPR000697(EVH1)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR044100|mint:Q9NSC5|rcsb pdb:2P8V|rcsb pdb:3CVF|reactome:R-HSA-6794361	refseq:NP_015294.1|sgd:S000005952|ensemblfungi:YPL031C(gene)|ensemblfungi:YPL031C_mRNA(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016242"(negative regulation of macroautophagy)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032878"(regulation of establishment or maintenance of cell polarity)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045719"(negative regulation of glycogen biosynthetic process)|go:"GO:0045936"(negative regulation of phosphate metabolic process)|go:"GO:0046822"(regulation of nucleocytoplasmic transport)|go:"GO:0050849"(negative regulation of calcium-mediated signaling)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0005737"(cytoplasm)|rcsb pdb:2PK9|rcsb pdb:2PMI|rcsb pdb:4KRC|rcsb pdb:4KRD|go:"GO:0005634"(nucleus)|go:"GO:0071073"(positive regulation of phospholipid biosynthetic process)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901987"(regulation of cell cycle phase transition)|go:"GO:1990860"(Pho85-Pho80 CDK-cyclin complex)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P17157|dip:DIP-1493N	-	-	crc64:246A4358870B00EC	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:U1y/y52nnf7zQUCNQlqk7JDgXi49606	rogid:hrRlpgrzGGTT3/GQ5x0LgsjaGeE559292	intact-crc:872B8E8DC5FD75D9|rigid:t1O3hmM+iD7DreqbG4upHbUR+uI	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9NSC5	uniprotkb:P32502	intact:EBI-748420|uniprotkb:O14580|uniprotkb:O95350|uniprotkb:Q9NSB9|uniprotkb:Q9NSC0|intact:EBI-2557809|uniprotkb:E9PCW9|uniprotkb:Q9NSC1|intact:EBI-28972925|ensembl:ENSP00000376162|ensembl:ENSP00000439937|ensembl:ENSP00000446026|intact:EBI-10175777|uniprotkb:B2RA10	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:home3_human(display_long)|uniprotkb:HOMER3(gene name)|psi-mi:HOMER3(display_short)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554548|imex:IM-24995-4208	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000221222|ensembl:ENSP00000221222|ensembl:ENSP00000376162|ensembl:ENST00000433218|ensembl:ENSP00000396154|ensembl:ENSP00000439937|ensembl:ENSP00000446026|ensembl:ENST00000594439|ensembl:ENSP00000471835|refseq:XP_006723006.1|refseq:XP_006723007.1|refseq:NP_001139193.1|refseq:NP_001139194.1|refseq:NP_004829.3|refseq:NP_001139196.1|ensembl:ENSG00000051128(gene)|ensembl:ENST00000392351(transcript)|ensembl:ENST00000539827(transcript)|ensembl:ENST00000542541(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006605"(protein targeting)|go:"GO:0007216"(G protein-coupled glutamate receptor signaling pathway)|go:"GO:0014069"(postsynaptic density)|go:"GO:0030425"(dendrite)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0035256"(G protein-coupled glutamate receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|go:"GO:2001256"(regulation of store-operated calcium entry)|interpro:IPR000697(EVH1)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR044100|mint:Q9NSC5|rcsb pdb:2P8V|rcsb pdb:3CVF|reactome:R-HSA-6794361	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731	-	-	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:U1y/y52nnf7zQUCNQlqk7JDgXi49606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:BCA2BABA43DA24DC|rigid:nQ/5cQZN/Z9bvMLr5D5+hLXF3n0	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P52286	uniprotkb:Q9NVF7	intact:EBI-4090|uniprotkb:Q07186|uniprotkb:D6VSW0|ensemblfungi:YDR328C	intact:EBI-740282|uniprotkb:O75070|ensembl:ENSP00000355827|uniprotkb:E9PEM8	psi-mi:skp1_yeast(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:CBF3D(gene name synonym)|uniprotkb:YDR328C(locus name)|uniprotkb:D9798.14(orf name)|uniprotkb:Centromere DNA-binding protein complex CBF3 subunit D(gene name synonym)|uniprotkb:E3 ubiquitin ligase complex SCF subunit SKP1(gene name synonym)	psi-mi:fbx28_human(display_long)|uniprotkb:FBXO28(gene name)|psi-mi:FBXO28(display_short)|uniprotkb:KIAA0483(gene name synonym)|uniprotkb:CENP-30(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554564|imex:IM-24995-4212	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002736|refseq:NP_010615.3|dip:DIP-1236N|mint:P52286|ensemblfungi:YDR328C(gene)|ensemblfungi:YDR328C_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0000921"(septin ring assembly)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0010458"(exit from mitosis)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031518"(CBF3 complex)|go:"GO:0034622"|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0043291"(RAVE complex)|go:"GO:0045116"(protein neddylation)|go:"GO:0051382"(kinetochore assembly)|go:"GO:0097602"(cullin family protein binding)|go:"GO:2000766"(negative regulation of cytoplasmic translation)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|rcsb pdb:1NEX|rcsb pdb:3MKS|rcsb pdb:3V7D|rcsb pdb:5AN3|rcsb pdb:6F07|rcsb pdb:6FE8|rcsb pdb:6GSA|rcsb pdb:6GYP|rcsb pdb:6GYS|rcsb pdb:6GYU|rcsb pdb:7K79|reactome:R-SCE-174113|reactome:R-SCE-68949|reactome:R-SCE-8854050|reactome:R-SCE-8951664|reactome:R-SCE-983168	refseq:NP_055991.1|ensembl:ENSG00000143756(gene)|ensembl:ENST00000366862(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000776"(kinetochore)|go:"GO:0042802"(identical protein binding)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR036047|interpro:IPR039719|refseq:NP_001129587.1|dip:DIP-56683N	-	crc64:746DDE6470A69432	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:HO5Uz+KzzWNBubxoXRDNTVi8eIA559292	rogid:Iz7yI5ugv60KqYH7MAdBjXjw2vs9606	intact-crc:325D2C602800E12F|rigid:9LW09gw2oiP7ymssRKHBhvSsnlc	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9NTW7	uniprotkb:Q12161	intact:EBI-711679|uniprotkb:Q9NTS7|uniprotkb:Q9NVH4|ensembl:ENSP00000355179|intact:EBI-10965088|intact:EBI-8637652|intact:MINT-8162399|intact:EBI-745730|uniprotkb:A2A2N4|uniprotkb:Q53H69|uniprotkb:Q53XQ1|uniprotkb:Q5JWM0|uniprotkb:Q5JWM1|uniprotkb:Q8WU98|uniprotkb:Q9H9P1|uniprotkb:Q9NPA5	intact:EBI-34372|uniprotkb:D6W213|ensemblfungi:YOL054W	psi-mi:zf64b_human(display_long)|uniprotkb:Zinc finger protein 338(gene name synonym)|uniprotkb:ZFP64(gene name)|psi-mi:ZFP64(display_short)|uniprotkb:ZNF338(gene name synonym)	psi-mi:psh1_yeast(display_long)|uniprotkb:PSH1(gene name)|psi-mi:PSH1(display_short)|uniprotkb:POB3/SPT16 histone-associated protein 1(gene name synonym)|uniprotkb:O1263(orf name)|uniprotkb:YOL054W(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554560|imex:IM-24995-4211	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_955459.2|ensembl:ENSG00000020256(gene)|ensembl:ENST00000361387(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|rcsb pdb:1X5W|rcsb pdb:2DMD|interpro:IPR036236|refseq:NP_001306075.1|refseq:NP_060667.2|refseq:NP_071371.3|refseq:NP_955458.1	refseq:NP_014587.1|sgd:S000005415|mint:Q12161|dip:DIP-6481N|ensemblfungi:YOL054W(gene)|ensemblfungi:YOL054W_mRNA(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907	-	-	crc64:CE0ECBCB6D465554	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2019/04/15	rogid:aTPOj1Ms8ghVMxTJUwnDUyonUQU9606	rogid:AvPMRd/GjfaTyQjEfMPhBVcvOs4559292	intact-crc:7E316D7364C93A76|rigid:H1grh63KX7jGkuDU2e4yb81EM2Q	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9NSC5	uniprotkb:P28004	intact:EBI-748420|uniprotkb:O14580|uniprotkb:O95350|uniprotkb:Q9NSB9|uniprotkb:Q9NSC0|intact:EBI-2557809|uniprotkb:E9PCW9|uniprotkb:Q9NSC1|intact:EBI-28972925|ensembl:ENSP00000376162|ensembl:ENSP00000439937|ensembl:ENSP00000446026|intact:EBI-10175777|uniprotkb:B2RA10	intact:EBI-20640|uniprotkb:D6VPI6|ensemblfungi:YAL032C	psi-mi:home3_human(display_long)|uniprotkb:HOMER3(gene name)|psi-mi:HOMER3(display_short)	psi-mi:prp45_yeast(display_long)|uniprotkb:YAL032C(locus name)|uniprotkb:PRP45(gene name)|psi-mi:PRP45(display_short)|uniprotkb:FUN20(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554540|imex:IM-24995-4206	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000221222|ensembl:ENSP00000221222|ensembl:ENSP00000376162|ensembl:ENST00000433218|ensembl:ENSP00000396154|ensembl:ENSP00000439937|ensembl:ENSP00000446026|ensembl:ENST00000594439|ensembl:ENSP00000471835|refseq:XP_006723006.1|refseq:XP_006723007.1|refseq:NP_001139193.1|refseq:NP_001139194.1|refseq:NP_004829.3|refseq:NP_001139196.1|ensembl:ENSG00000051128(gene)|ensembl:ENST00000392351(transcript)|ensembl:ENST00000539827(transcript)|ensembl:ENST00000542541(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006605"(protein targeting)|go:"GO:0007216"(G protein-coupled glutamate receptor signaling pathway)|go:"GO:0014069"(postsynaptic density)|go:"GO:0030425"(dendrite)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0035256"(G protein-coupled glutamate receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|go:"GO:2001256"(regulation of store-operated calcium entry)|interpro:IPR000697(EVH1)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR044100|mint:Q9NSC5|rcsb pdb:2P8V|rcsb pdb:3CVF|reactome:R-HSA-6794361	refseq:NP_009370.1|sgd:S000000030|ensemblfungi:YAL032C(gene)|ensemblfungi:YAL032C_mRNA(transcript)|go:"GO:0000350"(generation of catalytic spliceosome for second transesterification step)|go:"GO:0005634"(nucleus)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|interpro:IPR004015(SKIP/SNW)|interpro:IPR017862|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|dip:DIP-2774N|mint:P28004	-	-	crc64:FE5A724186D7FE84	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:U1y/y52nnf7zQUCNQlqk7JDgXi49606	rogid:qoHF1UsO3k+JOTOfigSuy2P84/k559292	intact-crc:6E7C56E8052E32AD|rigid:Eduwq3iPRqhvty7rIjhzv5EAGG8	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P39682	uniprotkb:Q9NSC5	intact:EBI-612|uniprotkb:D6VZC9|uniprotkb:E9P8Z1|ensemblfungi:YML046W	intact:EBI-748420|uniprotkb:O14580|uniprotkb:O95350|uniprotkb:Q9NSB9|uniprotkb:Q9NSC0|intact:EBI-2557809|uniprotkb:E9PCW9|uniprotkb:Q9NSC1|intact:EBI-28972925|ensembl:ENSP00000376162|ensembl:ENSP00000439937|ensembl:ENSP00000446026|intact:EBI-10175777|uniprotkb:B2RA10	psi-mi:prp39_yeast(display_long)|uniprotkb:YM9827.06(orf name)|uniprotkb:YML046W(locus name)|uniprotkb:PRP39(gene name)|psi-mi:PRP39(display_short)	psi-mi:home3_human(display_long)|uniprotkb:HOMER3(gene name)|psi-mi:HOMER3(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554552|imex:IM-24995-4209	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013667.1|sgd:S000004509|dip:DIP-812N|mint:P39682|ensemblfungi:YML046W(gene)|ensemblfungi:YML046W_mRNA(transcript)|go:"GO:0000243"(commitment complex)|go:"GO:0000395"(mRNA 5'-splice site recognition)|go:"GO:0005685"(U1 snRNP)|go:"GO:0071004"(U2-type prespliceosome)|interpro:IPR003107(RNA-processing protein, HAT helix)|interpro:IPR011990(Tetratricopeptide-like helical)|rcsb pdb:5ZWN|rcsb pdb:6G90|rcsb pdb:6N7P|rcsb pdb:6N7R|rcsb pdb:6N7X	ensembl:ENST00000221222|ensembl:ENSP00000221222|ensembl:ENSP00000376162|ensembl:ENST00000433218|ensembl:ENSP00000396154|ensembl:ENSP00000439937|ensembl:ENSP00000446026|ensembl:ENST00000594439|ensembl:ENSP00000471835|refseq:XP_006723006.1|refseq:XP_006723007.1|refseq:NP_001139193.1|refseq:NP_001139194.1|refseq:NP_004829.3|refseq:NP_001139196.1|ensembl:ENSG00000051128(gene)|ensembl:ENST00000392351(transcript)|ensembl:ENST00000539827(transcript)|ensembl:ENST00000542541(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006605"(protein targeting)|go:"GO:0007216"(G protein-coupled glutamate receptor signaling pathway)|go:"GO:0014069"(postsynaptic density)|go:"GO:0030425"(dendrite)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0035256"(G protein-coupled glutamate receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|go:"GO:2001256"(regulation of store-operated calcium entry)|interpro:IPR000697(EVH1)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR044100|mint:Q9NSC5|rcsb pdb:2P8V|rcsb pdb:3CVF|reactome:R-HSA-6794361	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:urVLzQFKnYT1bYOs3yRd9dd7lMk559292	rogid:U1y/y52nnf7zQUCNQlqk7JDgXi49606	intact-crc:27CCA4F8F4C87F9E|rigid:PoE+zlZR11lNp7vEcRbZ8w/iRpo	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9NSC5	uniprotkb:P35191	intact:EBI-748420|uniprotkb:O14580|uniprotkb:O95350|uniprotkb:Q9NSB9|uniprotkb:Q9NSC0|intact:EBI-2557809|uniprotkb:E9PCW9|uniprotkb:Q9NSC1|intact:EBI-28972925|ensembl:ENSP00000376162|ensembl:ENSP00000439937|ensembl:ENSP00000446026|intact:EBI-10175777|uniprotkb:B2RA10	intact:EBI-10603|ensemblfungi:YFL016C|uniprotkb:D6VTL4	psi-mi:home3_human(display_long)|uniprotkb:HOMER3(gene name)|psi-mi:HOMER3(display_short)	psi-mi:mdj1_yeast(display_long)|uniprotkb:YFL016C(locus name)|uniprotkb:MDJ1(gene name)|psi-mi:MDJ1(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554544|imex:IM-24995-4207	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000221222|ensembl:ENSP00000221222|ensembl:ENSP00000376162|ensembl:ENST00000433218|ensembl:ENSP00000396154|ensembl:ENSP00000439937|ensembl:ENSP00000446026|ensembl:ENST00000594439|ensembl:ENSP00000471835|refseq:XP_006723006.1|refseq:XP_006723007.1|refseq:NP_001139193.1|refseq:NP_001139194.1|refseq:NP_004829.3|refseq:NP_001139196.1|ensembl:ENSG00000051128(gene)|ensembl:ENST00000392351(transcript)|ensembl:ENST00000539827(transcript)|ensembl:ENST00000542541(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006605"(protein targeting)|go:"GO:0007216"(G protein-coupled glutamate receptor signaling pathway)|go:"GO:0014069"(postsynaptic density)|go:"GO:0030425"(dendrite)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0035256"(G protein-coupled glutamate receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|go:"GO:2001256"(regulation of store-operated calcium entry)|interpro:IPR000697(EVH1)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR044100|mint:Q9NSC5|rcsb pdb:2P8V|rcsb pdb:3CVF|reactome:R-HSA-6794361	ensemblfungi:YFL016C(gene)|ensemblfungi:YFL016C_mRNA(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0009408"(response to heat)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031314"(extrinsic component of mitochondrial inner membrane)|go:"GO:0042026"(protein refolding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|interpro:IPR001305(Heat shock protein DnaJ, cysteine-rich region)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR012724(Chaperone DnaJ)|interpro:IPR018253|interpro:IPR036410|interpro:IPR036869|go:"GO:0005759"(mitochondrial matrix)|refseq:NP_116638.1|sgd:S000001878|mint:P35191|dip:DIP-764N	-	-	crc64:007343427C66D2B6	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:U1y/y52nnf7zQUCNQlqk7JDgXi49606	rogid:2JbQztkUZ2kj7Y45Ghq1vTAhYdU559292	intact-crc:081E6CF540C63D93|rigid:bMATE5CfS2vO46/cf0YpYoWM7VY	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9NTM9	uniprotkb:P32502	intact:EBI-714918|uniprotkb:Q5TCZ8|uniprotkb:Q9Y321|ensembl:ENSP00000359507	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:cutc_human(display_long)|uniprotkb:CUTC(gene name)|psi-mi:CUTC(display_short)|uniprotkb:CGI-32(orf name)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554556|imex:IM-24995-4210	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000119929(gene)|ensembl:ENST00000370476(transcript)|go:"GO:0005507"(copper ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006825"(copper ion transport)|go:"GO:0051262"(protein tetramerization)|go:"GO:0055070"(copper ion homeostasis)|interpro:IPR005627(CutC)|interpro:IPR023648|interpro:IPR036822|mint:Q9NTM9|refseq:NP_057044.2|reactome:R-HSA-936837|rcsb pdb:3IWP	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731	-	-	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:MkxQTQ5IGq+/IZzPy3wSurdtB6w9606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:0E3988469D3BD60B|rigid:QuTE3NJKYsTVaEHhlnQxe8Ufvpc	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9NVV9	uniprotkb:P38340	intact:EBI-741515|uniprotkb:Q53FQ1|uniprotkb:Q6IA99|ensembl:ENSP00000254250|uniprotkb:A6NCB6|uniprotkb:D3DSY5|uniprotkb:H9KV49	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:thap1_human(display_long)|uniprotkb:THAP1(gene name)|psi-mi:THAP1(display_short)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554588|imex:IM-24995-4218	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060575.1|ensembl:ENSG00000131931(gene)|ensembl:ENST00000254250(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001650"(fibrillar center)|go:"GO:0001935"(endothelial cell proliferation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007049"(cell cycle)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016605"(PML body)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR006612(Zinc finger, C2CH-type)|interpro:IPR026516|interpro:IPR038441|mint:Q9NVV9|rcsb pdb:2JTG|rcsb pdb:2KO0|rcsb pdb:2L1G|refseq:NP_945354.1	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F	-	-	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:/KO90pu5tBnIVq9SMx1JYPXFCEQ9606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:46806989A8F0C32D|rigid:nXSsDqXxvAuQuiN3QMDBNnUTHxk	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9NVV9	uniprotkb:P35184	intact:EBI-741515|uniprotkb:Q53FQ1|uniprotkb:Q6IA99|ensembl:ENSP00000254250|uniprotkb:A6NCB6|uniprotkb:D3DSY5|uniprotkb:H9KV49	intact:EBI-17971|uniprotkb:D6VVU2|ensemblfungi:YIR012W	psi-mi:thap1_human(display_long)|uniprotkb:THAP1(gene name)|psi-mi:THAP1(display_short)	psi-mi:sqt1_yeast(display_long)|uniprotkb:YIB12W(orf name)|uniprotkb:YIR012W(locus name)|uniprotkb:SQT1(gene name)|psi-mi:SQT1(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554584|imex:IM-24995-4217	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060575.1|ensembl:ENSG00000131931(gene)|ensembl:ENST00000254250(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001650"(fibrillar center)|go:"GO:0001935"(endothelial cell proliferation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007049"(cell cycle)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016605"(PML body)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR006612(Zinc finger, C2CH-type)|interpro:IPR026516|interpro:IPR038441|mint:Q9NVV9|rcsb pdb:2JTG|rcsb pdb:2KO0|rcsb pdb:2L1G|refseq:NP_945354.1	refseq:NP_012277.1|sgd:S000001451|ensemblfungi:YIR012W_mRNA(transcript)|ensemblfungi:YIR012W(gene)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|rcsb pdb:4ZOV|rcsb pdb:4ZOX|rcsb pdb:5AMS|dip:DIP-2508N|mint:P35184	-	-	crc64:981D566076B0C881	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:/KO90pu5tBnIVq9SMx1JYPXFCEQ9606	rogid:u/Q5uAjR85ZD3op0nHiN20IVCLY559292	intact-crc:083DF4FAAB6AC82F|rigid:MYQZw2Ov9iO6TKFJqd/zpvZgQTc	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P25372	uniprotkb:Q9NVV9	intact:EBI-19616|uniprotkb:D6VR84|ensemblfungi:YCR083W	intact:EBI-741515|uniprotkb:Q53FQ1|uniprotkb:Q6IA99|ensembl:ENSP00000254250|uniprotkb:A6NCB6|uniprotkb:D3DSY5|uniprotkb:H9KV49	psi-mi:trx3_yeast(display_long)|uniprotkb:TRX3(gene name)|psi-mi:TRX3(display_short)|uniprotkb:YCR83W(orf name)|uniprotkb:YCR083W(locus name)	psi-mi:thap1_human(display_long)|uniprotkb:THAP1(gene name)|psi-mi:THAP1(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554568|imex:IM-24995-4213	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR036249|refseq:NP_010006.1|sgd:S000000679|interpro:IPR017937|interpro:IPR013766(Thioredoxin domain)|rcsb pdb:2OE0|rcsb pdb:2OE1|rcsb pdb:2OE3|ensemblfungi:YCR083W(gene)|ensemblfungi:YCR083W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0015036"(disulfide oxidoreductase activity)|go:"GO:0034599"(cellular response to oxidative stress)|rcsb pdb:5YKW	refseq:NP_060575.1|ensembl:ENSG00000131931(gene)|ensembl:ENST00000254250(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001650"(fibrillar center)|go:"GO:0001935"(endothelial cell proliferation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007049"(cell cycle)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016605"(PML body)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR006612(Zinc finger, C2CH-type)|interpro:IPR026516|interpro:IPR038441|mint:Q9NVV9|rcsb pdb:2JTG|rcsb pdb:2KO0|rcsb pdb:2L1G|refseq:NP_945354.1	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:g0xjGf9GvJRl8iv2qoT5tOs7jXI559292	rogid:/KO90pu5tBnIVq9SMx1JYPXFCEQ9606	intact-crc:8AD336E6C14784C0|rigid:gt2+hlOW9j2rlOxnM5RKPuBqBs4	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9NVV9	uniprotkb:Q02821	intact:EBI-741515|uniprotkb:Q53FQ1|uniprotkb:Q6IA99|ensembl:ENSP00000254250|uniprotkb:A6NCB6|uniprotkb:D3DSY5|uniprotkb:H9KV49	intact:EBI-1797|uniprotkb:D6W0Z8|ensemblfungi:YNL189W	psi-mi:thap1_human(display_long)|uniprotkb:THAP1(gene name)|psi-mi:THAP1(display_short)	psi-mi:ima1_yeast(display_long)|uniprotkb:SRP1(gene name)|psi-mi:SRP1(display_short)|uniprotkb:KAP60(gene name synonym)|uniprotkb:YNL189W(locus name)|uniprotkb:N1606(orf name)|uniprotkb:Karyopherin subunit alpha(gene name synonym)|uniprotkb:Karyopherin-60(gene name synonym)|uniprotkb:Serine-rich RNA polymerase I suppressor protein(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554576|imex:IM-24995-4215	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060575.1|ensembl:ENSG00000131931(gene)|ensembl:ENST00000254250(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001650"(fibrillar center)|go:"GO:0001935"(endothelial cell proliferation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007049"(cell cycle)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016605"(PML body)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR006612(Zinc finger, C2CH-type)|interpro:IPR026516|interpro:IPR038441|mint:Q9NVV9|rcsb pdb:2JTG|rcsb pdb:2KO0|rcsb pdb:2L1G|refseq:NP_945354.1	refseq:NP_014210.1|sgd:S000005133|dip:DIP-728N|mint:Q02821|ensemblfungi:YNL189W(gene)|ensemblfungi:YNL189W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0031144"(proteasome localization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042564"(NLS-dependent protein nuclear import complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|rcsb pdb:1BK5|rcsb pdb:1BK6|rcsb pdb:1EE4|rcsb pdb:1EE5|rcsb pdb:1UN0|rcsb pdb:1WA5|rcsb pdb:2C1T|rcsb pdb:4PVZ|rcsb pdb:4XZR|rcsb pdb:5H2W|rcsb pdb:5H2X|rcsb pdb:5T94	-	-	crc64:8D3A0CB76F2E7C00	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:/KO90pu5tBnIVq9SMx1JYPXFCEQ9606	rogid:NyzC93xnBCb8DX/AH346lwg4u2A559292	intact-crc:B3E03FA6A70AC490|rigid:x/UGKue0dWbjDEhVKK+hw+DNx6Q	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9NVV9	uniprotkb:Q12259	intact:EBI-741515|uniprotkb:Q53FQ1|uniprotkb:Q6IA99|ensembl:ENSP00000254250|uniprotkb:A6NCB6|uniprotkb:D3DSY5|uniprotkb:H9KV49	intact:EBI-30776|uniprotkb:D6VYA8|ensemblfungi:YLR108C	psi-mi:thap1_human(display_long)|uniprotkb:THAP1(gene name)|psi-mi:THAP1(display_short)	psi-mi:yl108_yeast(display_long)|uniprotkb:L2913(orf name)|uniprotkb:YLR108C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554572|imex:IM-24995-4214	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060575.1|ensembl:ENSG00000131931(gene)|ensembl:ENST00000254250(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001650"(fibrillar center)|go:"GO:0001935"(endothelial cell proliferation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007049"(cell cycle)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016605"(PML body)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR006612(Zinc finger, C2CH-type)|interpro:IPR026516|interpro:IPR038441|mint:Q9NVV9|rcsb pdb:2JTG|rcsb pdb:2KO0|rcsb pdb:2L1G|refseq:NP_945354.1	refseq:NP_013209.1|sgd:S000004098|dip:DIP-4075N|ensemblfungi:YLR108C(gene)|ensemblfungi:YLR108C_mRNA(transcript)|go:"GO:0005634"(nucleus)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:/KO90pu5tBnIVq9SMx1JYPXFCEQ9606	rogid:CzknxXhhvgMp3J0/oi197EgZ05U559292	intact-crc:633295CB0A09272F|rigid:HPH0K7k7xwZtExAi0j4OHsry67o	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P32502	uniprotkb:Q9NVV9	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	intact:EBI-741515|uniprotkb:Q53FQ1|uniprotkb:Q6IA99|ensembl:ENSP00000254250|uniprotkb:A6NCB6|uniprotkb:D3DSY5|uniprotkb:H9KV49	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:thap1_human(display_long)|uniprotkb:THAP1(gene name)|psi-mi:THAP1(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554580|imex:IM-24995-4216	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731	refseq:NP_060575.1|ensembl:ENSG00000131931(gene)|ensembl:ENST00000254250(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001650"(fibrillar center)|go:"GO:0001935"(endothelial cell proliferation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007049"(cell cycle)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016605"(PML body)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR006612(Zinc finger, C2CH-type)|interpro:IPR026516|interpro:IPR038441|mint:Q9NVV9|rcsb pdb:2JTG|rcsb pdb:2KO0|rcsb pdb:2L1G|refseq:NP_945354.1	-	crc64:A5409FAF1594854C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	rogid:/KO90pu5tBnIVq9SMx1JYPXFCEQ9606	intact-crc:C119C34BF5E51B00|rigid:WfQwtYrbxl994hjGKdwyREUxCyI	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P47086	uniprotkb:Q9NWT6	intact:EBI-26299|uniprotkb:D6VWI7|uniprotkb:Q6Q5N5|ensemblfungi:YJR011C	intact:EBI-745632|uniprotkb:Q969Q7|uniprotkb:Q9NPV5|uniprotkb:Q5W147|ensembl:ENSP00000299163|uniprotkb:D3DR69	psi-mi:yjy1_yeast(display_long)|uniprotkb:J1438(orf name)|uniprotkb:YJR83.26(orf name)|uniprotkb:YJR011C(locus name)	psi-mi:hif1n_human(display_long)|uniprotkb:Hypoxia-inducible factor asparagine hydroxylase(gene name synonym)|uniprotkb:Factor inhibiting HIF-1(gene name synonym)|uniprotkb:HIF1AN(gene name)|psi-mi:HIF1AN(display_short)|uniprotkb:FIH1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554616|imex:IM-24995-4225	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003772|refseq:NP_012545.1|mint:P47086|dip:DIP-5694N|ensemblfungi:YJR011C(gene)|ensemblfungi:YJR011C_mRNA(transcript)	refseq:NP_060372.2|ensembl:ENSG00000166135(gene)|ensembl:ENST00000299163(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0036138"(peptidyl-histidine hydroxylation)|go:"GO:0036139"(peptidyl-histidine dioxygenase activity)|go:"GO:0036140"(peptidyl-asparagine 3-dioxygenase activity)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0042265"(peptidyl-asparagine hydroxylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0102113"(hypoxia-inducible factor-asparagine oxygenase activity)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027445|interpro:IPR027452|interpro:IPR041667|mint:Q9NWT6|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1H2N|rcsb pdb:1IZ3|rcsb pdb:1MZE|rcsb pdb:1MZF|rcsb pdb:1YCI|rcsb pdb:2CGN|rcsb pdb:2CGO|rcsb pdb:2ILM|rcsb pdb:2W0X|rcsb pdb:2WA3|rcsb pdb:2WA4|rcsb pdb:2XUM|rcsb pdb:2Y0I|rcsb pdb:2YC0|rcsb pdb:2YDE|rcsb pdb:3D8C|rcsb pdb:3KCX|rcsb pdb:3KCY|rcsb pdb:3OD4|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:4AI8|rcsb pdb:4B7E|rcsb pdb:4B7K|rcsb pdb:4BIO|rcsb pdb:4JAA|rcsb pdb:4NR1|rcsb pdb:4Z1V|rcsb pdb:4Z2W|rcsb pdb:5JWK|rcsb pdb:5JWL|rcsb pdb:5JWP|rcsb pdb:5OP6|rcsb pdb:6H9J|rcsb pdb:6HA6|rcsb pdb:6HC8|rcsb pdb:6HKP|rcsb pdb:6HL5|rcsb pdb:6HL6|rcsb pdb:6RUJ|reactome:R-HSA-1234174|rcsb pdb:5OP8|rcsb pdb:5OPC|dip:DIP-35527N	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:b7YXohJEN6FMN8gYKAKboZQkxvQ559292	rogid:lvPtfqlB1+hOcdCAwcopj/Yl+3Y9606	intact-crc:A7CE2C78862AA9DF|rigid:nR1XPi9ZWReYQ/dZTk2ZSoxjNy4	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9NWS6	uniprotkb:P32502	intact:EBI-8638992|uniprotkb:B4DY02|ensembl:ENSP00000216214|ensembl:ENSP00000395892|intact:MINT-8162875|uniprotkb:Q5TII5|uniprotkb:B3KWG4|uniprotkb:Q96CY3	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:f118a_human(display_long)|uniprotkb:FAM118A(gene name)|psi-mi:FAM118A(display_short)|uniprotkb:C22orf8(gene name synonym)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554612|imex:IM-24995-4224	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000100376(gene)|ensembl:ENST00000216214(transcript)|ensembl:ENST00000441876(transcript)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|interpro:IPR033353|interpro:IPR038916|interpro:IPR039444|refseq:NP_060381.2|refseq:NP_001098065.1	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731	-	comment:mint	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:zZMOyeZwAeoDNLBQ9EKYRw4+0BM9606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:5D65BC7313364EAD|rigid:r/x3t0aXwgqnxLaZbMM7TomZnds	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9NWS6	uniprotkb:Q12259	intact:EBI-8638992|uniprotkb:B4DY02|ensembl:ENSP00000216214|ensembl:ENSP00000395892|intact:MINT-8162875|uniprotkb:Q5TII5|uniprotkb:B3KWG4|uniprotkb:Q96CY3	intact:EBI-30776|uniprotkb:D6VYA8|ensemblfungi:YLR108C	psi-mi:f118a_human(display_long)|uniprotkb:FAM118A(gene name)|psi-mi:FAM118A(display_short)|uniprotkb:C22orf8(gene name synonym)	psi-mi:yl108_yeast(display_long)|uniprotkb:L2913(orf name)|uniprotkb:YLR108C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554608|imex:IM-24995-4223	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000100376(gene)|ensembl:ENST00000216214(transcript)|ensembl:ENST00000441876(transcript)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|interpro:IPR033353|interpro:IPR038916|interpro:IPR039444|refseq:NP_060381.2|refseq:NP_001098065.1	refseq:NP_013209.1|sgd:S000004098|dip:DIP-4075N|ensemblfungi:YLR108C(gene)|ensemblfungi:YLR108C_mRNA(transcript)|go:"GO:0005634"(nucleus)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)	-	comment:mint	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:zZMOyeZwAeoDNLBQ9EKYRw4+0BM9606	rogid:CzknxXhhvgMp3J0/oi197EgZ05U559292	intact-crc:81652F3F29723443|rigid:T1dDPKLlQd2I0aehmcKfvO0ceZU	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P53829	uniprotkb:Q9NVV9	intact:EBI-28306|uniprotkb:D6W0Q5|ensemblfungi:YNL288W	intact:EBI-741515|uniprotkb:Q53FQ1|uniprotkb:Q6IA99|ensembl:ENSP00000254250|uniprotkb:A6NCB6|uniprotkb:D3DSY5|uniprotkb:H9KV49	psi-mi:caf40_yeast(display_long)|uniprotkb:YNL288W(locus name)|uniprotkb:N0540(orf name)|uniprotkb:40 kDa CCR4-associated factor(gene name synonym)|uniprotkb:CAF40(gene name)|psi-mi:CAF40(display_short)	psi-mi:thap1_human(display_long)|uniprotkb:THAP1(gene name)|psi-mi:THAP1(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554592|imex:IM-24995-4219	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014111.1|sgd:S000005232|dip:DIP-1995N|mint:P53829|ensemblfungi:YNL288W(gene)|ensemblfungi:YNL288W_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR007216(Cell differentiation, Rcd1-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:4CV5	refseq:NP_060575.1|ensembl:ENSG00000131931(gene)|ensembl:ENST00000254250(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001650"(fibrillar center)|go:"GO:0001935"(endothelial cell proliferation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007049"(cell cycle)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016605"(PML body)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR006612(Zinc finger, C2CH-type)|interpro:IPR026516|interpro:IPR038441|mint:Q9NVV9|rcsb pdb:2JTG|rcsb pdb:2KO0|rcsb pdb:2L1G|refseq:NP_945354.1	-	crc64:F3DBABE6AD3C7F3C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:etuSSgFGQOcgxPDexEXUqQg6H5s559292	rogid:/KO90pu5tBnIVq9SMx1JYPXFCEQ9606	intact-crc:3245A9D16F61834F|rigid:EOb1ad62YBbD7PDY8Bl/GbqC7i0	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9NVV9	uniprotkb:Q12161	intact:EBI-741515|uniprotkb:Q53FQ1|uniprotkb:Q6IA99|ensembl:ENSP00000254250|uniprotkb:A6NCB6|uniprotkb:D3DSY5|uniprotkb:H9KV49	intact:EBI-34372|uniprotkb:D6W213|ensemblfungi:YOL054W	psi-mi:thap1_human(display_long)|uniprotkb:THAP1(gene name)|psi-mi:THAP1(display_short)	psi-mi:psh1_yeast(display_long)|uniprotkb:PSH1(gene name)|psi-mi:PSH1(display_short)|uniprotkb:POB3/SPT16 histone-associated protein 1(gene name synonym)|uniprotkb:O1263(orf name)|uniprotkb:YOL054W(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554600|imex:IM-24995-4221	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060575.1|ensembl:ENSG00000131931(gene)|ensembl:ENST00000254250(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001650"(fibrillar center)|go:"GO:0001935"(endothelial cell proliferation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007049"(cell cycle)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016605"(PML body)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR006612(Zinc finger, C2CH-type)|interpro:IPR026516|interpro:IPR038441|mint:Q9NVV9|rcsb pdb:2JTG|rcsb pdb:2KO0|rcsb pdb:2L1G|refseq:NP_945354.1	refseq:NP_014587.1|sgd:S000005415|mint:Q12161|dip:DIP-6481N|ensemblfungi:YOL054W(gene)|ensemblfungi:YOL054W_mRNA(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907	-	-	crc64:CE0ECBCB6D465554	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:/KO90pu5tBnIVq9SMx1JYPXFCEQ9606	rogid:AvPMRd/GjfaTyQjEfMPhBVcvOs4559292	intact-crc:A2596DBF1ED2C4EB|rigid:cAs9Rb52eg8KN0sVdXYKvRhbD7E	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9NVV9	uniprotkb:P53335	intact:EBI-741515|uniprotkb:Q53FQ1|uniprotkb:Q6IA99|ensembl:ENSP00000254250|uniprotkb:A6NCB6|uniprotkb:D3DSY5|uniprotkb:H9KV49	intact:EBI-23652|uniprotkb:D6VV57|uniprotkb:Q8TG89|intact:EBI-33325|ensemblfungi:YGR280C	psi-mi:thap1_human(display_long)|uniprotkb:THAP1(gene name)|psi-mi:THAP1(display_short)	psi-mi:pxr1_yeast(display_long)|uniprotkb:PXR1(gene name)|psi-mi:PXR1(display_short)|uniprotkb:GNO1(gene name synonym)|uniprotkb:PinX1-related protein 1(gene name synonym)|uniprotkb:G-patch nucleolar protein(gene name synonym)|uniprotkb:YGR280C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554596|imex:IM-24995-4220	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060575.1|ensembl:ENSG00000131931(gene)|ensembl:ENST00000254250(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001650"(fibrillar center)|go:"GO:0001935"(endothelial cell proliferation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007049"(cell cycle)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016605"(PML body)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR006612(Zinc finger, C2CH-type)|interpro:IPR026516|interpro:IPR038441|mint:Q9NVV9|rcsb pdb:2JTG|rcsb pdb:2KO0|rcsb pdb:2L1G|refseq:NP_945354.1	refseq:NP_011796.1|sgd:S000003512|dip:DIP-4308N|mint:P53335|ensemblfungi:YGR280C(gene)|ensemblfungi:YGR280C_mRNA(transcript)|go:"GO:0000494"(box C/D RNA 3'-end processing)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0010521"(telomerase inhibitor activity)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|interpro:IPR000467(D111/G-patch)	-	-	crc64:D5AB6EB2C129922D	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:/KO90pu5tBnIVq9SMx1JYPXFCEQ9606	rogid:SzQtp13uvK3KbuNHyZQPJxKMzwY559292	intact-crc:2029660936EE3776|rigid:3ht2BQNn8IjNP9ovA40HOmWiBTc	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9NWS6	uniprotkb:P38340	intact:EBI-8638992|uniprotkb:B4DY02|ensembl:ENSP00000216214|ensembl:ENSP00000395892|intact:MINT-8162875|uniprotkb:Q5TII5|uniprotkb:B3KWG4|uniprotkb:Q96CY3	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:f118a_human(display_long)|uniprotkb:FAM118A(gene name)|psi-mi:FAM118A(display_short)|uniprotkb:C22orf8(gene name synonym)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554604|imex:IM-24995-4222	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000100376(gene)|ensembl:ENST00000216214(transcript)|ensembl:ENST00000441876(transcript)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|interpro:IPR033353|interpro:IPR038916|interpro:IPR039444|refseq:NP_060381.2|refseq:NP_001098065.1	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F	-	comment:mint	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:zZMOyeZwAeoDNLBQ9EKYRw4+0BM9606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:FBCE9E55FC6ABDF5|rigid:ViXk1gZdB3sdHGkhG4tOPMJF124	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9NYB9-2	uniprotkb:Q03782	intact:EBI-11096309|ensembl:ENSP00000261017	intact:EBI-627|uniprotkb:D6VSM1|ensemblfungi:YDR240C	psi-mi:q9nyb9-2(display_long)|uniprotkb:ABI2(gene name)|psi-mi:ABI2(display_short)|uniprotkb:ARGBPIA(gene name synonym)|uniprotkb:Abelson interactor 2(gene name synonym)|uniprotkb:Abl-binding protein 3(gene name synonym)|uniprotkb:Arg-binding protein 1(gene name synonym)	psi-mi:snu56_yeast(display_long)|uniprotkb:YDR240C(locus name)|uniprotkb:SNU56(gene name)|psi-mi:SNU56(display_short)|uniprotkb:MUD10(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554636|imex:IM-24995-4230	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-743598(isoform-parent)|ensembl:ENSG00000138443(gene)|ensembl:ENST00000261017(transcript)|uniprotkb:Q9NYB9-2(isoform-parent)	sgd:S000002648|refseq:NP_010526.1|dip:DIP-6514N|mint:Q03782|ensemblfungi:YDR240C(gene)|ensemblfungi:YDR240C_mRNA(transcript)|go:"GO:0000243"(commitment complex)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005685"(U1 snRNP)|go:"GO:0071004"(U2-type prespliceosome)|interpro:IPR043954|rcsb pdb:5ZWN|rcsb pdb:6G90|rcsb pdb:6N7P|rcsb pdb:6N7R|rcsb pdb:6N7X	-	-	crc64:5E0C7A1FD577808F	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:VNi9aUeavD8+CCi+n1DXS+7mmbs9606	rogid:gz3aUh/8pFF7Yn8XS9gdhSWrVNs559292	intact-crc:421598567B680617|rigid:9EPgDys2FUgB+pXASx5eV7k66h4	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q12446	uniprotkb:Q9NYB9-2	intact:EBI-10022|uniprotkb:D6W2N7|ensemblfungi:YOR181W	intact:EBI-11096309|ensembl:ENSP00000261017	psi-mi:las17_yeast(display_long)|uniprotkb:LAS17(gene name)|psi-mi:LAS17(display_short)|uniprotkb:YOR181W(locus name)	psi-mi:q9nyb9-2(display_long)|uniprotkb:ABI2(gene name)|psi-mi:ABI2(display_short)|uniprotkb:ARGBPIA(gene name synonym)|uniprotkb:Abelson interactor 2(gene name synonym)|uniprotkb:Abl-binding protein 3(gene name synonym)|uniprotkb:Arg-binding protein 1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554632|imex:IM-24995-4229	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014824.1|sgd:S000005707|ensemblfungi:YOR181W(gene)|ensemblfungi:YOR181W_mRNA(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007015"(actin filament organization)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030479"(actin cortical patch)|go:"GO:0032233"(positive regulation of actin filament bundle assembly)|go:"GO:0043332"(mating projection tip)|go:"GO:0045010"(actin nucleation)|go:"GO:0051666"(actin cortical patch localization)|go:"GO:0071933"(Arp2/3 complex binding)|go:"GO:0140224"(SLAC complex)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR000697(EVH1)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR027641|interpro:IPR033927|rcsb pdb:1ZUK|dip:DIP-963N|mint:Q12446	intact:EBI-743598(isoform-parent)|ensembl:ENSG00000138443(gene)|ensembl:ENST00000261017(transcript)|uniprotkb:Q9NYB9-2(isoform-parent)	-	crc64:4488355563AA2645	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:TfQ256gBQPp1T8Ntu2AvktFnypA559292	rogid:VNi9aUeavD8+CCi+n1DXS+7mmbs9606	intact-crc:A67FEE4B3F594A17|rigid:sfFzHpyPEZSJfLqmdNn/LCsybpA	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P08458	uniprotkb:Q9NWX6	intact:EBI-17889|uniprotkb:D6VTE3|ensemblfungi:YDR523C	intact:EBI-746510|uniprotkb:Q53G12|uniprotkb:Q7L5R3|uniprotkb:Q9H0S2|uniprotkb:D3DQJ5|ensembl:ENSP00000231198	psi-mi:sps1_yeast(display_long)|uniprotkb:D9719.27(orf name)|uniprotkb:YDR523C(locus name)|uniprotkb:SPS1(gene name)|psi-mi:SPS1(display_short)	psi-mi:thg1_human(display_long)|uniprotkb:Induced in high glucose-1(gene name synonym)|uniprotkb:tRNA-histidine guanylyltransferase(gene name synonym)|uniprotkb:Interphase cytoplasmic foci protein 45(gene name synonym)|uniprotkb:THG1L(gene name)|psi-mi:THG1L(display_short)|uniprotkb:ICF45(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554620|imex:IM-24995-4226	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010811.1|sgd:S000002931|ensemblfungi:YDR523C(gene)|ensemblfungi:YDR523C_mRNA(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005628"(prospore membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0030437"(ascospore formation)|go:"GO:0030476"(ascospore wall assembly)|go:"GO:0051229"(meiotic spindle disassembly)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903024"(positive regulation of ascospore-type prospore membrane formation)|go:"GO:1904750"(negative regulation of protein localization to nucleolus)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|dip:DIP-6598N|mint:P08458	refseq:NP_001304753.1|refseq:NP_001304754.1|refseq:NP_001304755.1|refseq:NP_060342.2|ensembl:ENSG00000113272(gene)|ensembl:ENST00000231198(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006400"(tRNA modification)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008033"(tRNA processing)|go:"GO:0008053"(mitochondrial fusion)|go:"GO:0008193"(tRNA guanylyltransferase activity)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0051289"(protein homotetramerization)|go:"GO:1990046"(stress-induced mitochondrial fusion)|go:"GO:1990234"(transferase complex)|interpro:IPR007537(tRNAHis guanylyltransferase)|interpro:IPR024956|interpro:IPR025845|interpro:IPR038469|rcsb pdb:3OTB|rcsb pdb:3OTC|rcsb pdb:3OTD|rcsb pdb:3OTE|rcsb pdb:7CV1|reactome:R-HSA-6782315|dip:DIP-59479N	-	crc64:6143055E85BAF4FF	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:icg6ZPlLWE0X6aii9Onq9FVzOuM559292	rogid:P1Q3muoqX06qZw9Xu0Gz5f8ALv49606	intact-crc:17DBE255054929FE|rigid:SrDa8HKNeMAkeD8LtzmHv59JIFQ	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q12015	uniprotkb:Q9NX47	intact:EBI-31423|uniprotkb:D6W2S8|ensemblfungi:YOR223W	intact:EBI-2341610|ensembl:ENSP00000351813	psi-mi:dsc3_yeast(display_long)|uniprotkb:DSC3(gene name)|psi-mi:DSC3(display_short)|uniprotkb:Defective for SREBP cleavage protein 3(gene name synonym)|uniprotkb:YOR50-13(orf name)|uniprotkb:YOR223W(locus name)	psi-mi:marh5_human(display_long)|uniprotkb:MARCH5(gene name synonym)|uniprotkb:Membrane-associated RING finger protein 5(gene name synonym)|uniprotkb:Membrane-associated RING-CH protein V(gene name synonym)|uniprotkb:Mitochondrial ubiquitin ligase(gene name synonym)|uniprotkb:RING finger protein 153(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase MARCHF5(gene name synonym)|uniprotkb:MARCHF5(gene name)|psi-mi:MARCHF5(display_short)|uniprotkb:RNF153(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554624|imex:IM-24995-4227	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014866.3|sgd:S000005749|interpro:IPR019413|interpro:IPR025390|ensemblfungi:YOR223W(gene)|ensemblfungi:YOR223W_mRNA(transcript)|go:"GO:0000328"(fungal-type vacuole lumen)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016485"(protein processing)|go:"GO:0044695"(Dsc E3 ubiquitin ligase complex)	refseq:NP_060294.1|ensembl:ENSG00000198060(gene)|ensembl:ENST00000358935(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0051020"(GTPase binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070585"(protein localization to mitochondrion)|go:"GO:0090140"(regulation of mitochondrial fission)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0090344"(negative regulation of cell aging)|interpro:IPR011016(Zinc finger, variant RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|mint:Q9NX47	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:ebWSvkqYXzLugE3xFfu285Cil8Y559292	rogid:/w+L/oINlKM5ZSm1OkI+R+8PxXg9606	intact-crc:0A5F338405D3D6F2|rigid:i4kciKb1mhGdajNeZoHVy8oStDY	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P52286	uniprotkb:Q9NXK8	intact:EBI-4090|uniprotkb:Q07186|uniprotkb:D6VSW0|ensemblfungi:YDR328C	intact:EBI-719790|uniprotkb:Q9H5K4|uniprotkb:B3KSJ8|ensembl:ENSP00000247977	psi-mi:skp1_yeast(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:CBF3D(gene name synonym)|uniprotkb:YDR328C(locus name)|uniprotkb:D9798.14(orf name)|uniprotkb:Centromere DNA-binding protein complex CBF3 subunit D(gene name synonym)|uniprotkb:E3 ubiquitin ligase complex SCF subunit SKP1(gene name synonym)	psi-mi:fxl12_human(display_long)|uniprotkb:F-box and leucine-rich repeat protein 12(gene name synonym)|uniprotkb:F-box protein FBL12(gene name synonym)|uniprotkb:FBXL12(gene name)|psi-mi:FBXL12(display_short)|uniprotkb:FBL12(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554628|imex:IM-24995-4228	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002736|refseq:NP_010615.3|dip:DIP-1236N|mint:P52286|ensemblfungi:YDR328C(gene)|ensemblfungi:YDR328C_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0000921"(septin ring assembly)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0010458"(exit from mitosis)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031518"(CBF3 complex)|go:"GO:0034622"|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0043291"(RAVE complex)|go:"GO:0045116"(protein neddylation)|go:"GO:0051382"(kinetochore assembly)|go:"GO:0097602"(cullin family protein binding)|go:"GO:2000766"(negative regulation of cytoplasmic translation)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|rcsb pdb:1NEX|rcsb pdb:3MKS|rcsb pdb:3V7D|rcsb pdb:5AN3|rcsb pdb:6F07|rcsb pdb:6FE8|rcsb pdb:6GSA|rcsb pdb:6GYP|rcsb pdb:6GYS|rcsb pdb:6GYU|rcsb pdb:7K79|reactome:R-SCE-174113|reactome:R-SCE-68949|reactome:R-SCE-8854050|reactome:R-SCE-8951664|reactome:R-SCE-983168	refseq:NP_060173.1|refseq:NP_001303865.1|refseq:NP_001303866.1|refseq:NP_001303867.1|refseq:NP_001303868.1|refseq:NP_001303869.1|refseq:NP_001303870.1|refseq:NP_001303871.1|ensembl:ENSG00000127452(gene)|ensembl:ENST00000247977(transcript)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR032675|interpro:IPR036047|mint:Q9NXK8|reactome:R-HSA-8951664|reactome:R-HSA-983168	-	crc64:746DDE6470A69432	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:HO5Uz+KzzWNBubxoXRDNTVi8eIA559292	rogid:b+3vZLMbZvEww+hdTa3YnLkPiC49606	intact-crc:DE6BC8598133DB8C|rigid:YrtKB5yhPOVeqJBX+IeEhvzitc4	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q12208	uniprotkb:Q9P1Z2	intact:EBI-31589|uniprotkb:D6VYC7|ensemblfungi:YLR132C	intact:EBI-749920|uniprotkb:B3KVA8|uniprotkb:Q6FI59|uniprotkb:Q71RC3|uniprotkb:Q86WF8|uniprotkb:Q96JU3|uniprotkb:Q9H090|intact:EBI-2558801|ensembl:ENSP00000449960	psi-mi:usb1_yeast(display_long)|uniprotkb:USB1(gene name)|psi-mi:USB1(display_short)|uniprotkb:U six biogenesis protein 1(gene name synonym)|uniprotkb:L3127(orf name)|uniprotkb:YLR132C(locus name)	psi-mi:caco1_human(display_long)|uniprotkb:CALCOCO1(gene name)|psi-mi:CALCOCO1(display_short)|uniprotkb:KIAA1536(gene name synonym)|uniprotkb:Calphoglin(gene name synonym)|uniprotkb:Sarcoma antigen NY-SAR-3(gene name synonym)|uniprotkb:Coiled-coil coactivator protein(gene name synonym)|uniprotkb:PP13275(orf name)|uniprotkb:UNQ2436/PRO4996(orf name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554664|imex:IM-24995-4237	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013233.1|sgd:S000004122|dip:DIP-2147N|mint:Q12208|ensemblfungi:YLR132C(gene)|ensemblfungi:YLR132C_mRNA(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0008663"(2',3'-cyclic-nucleotide 2'-phosphodiesterase activity)|go:"GO:0034477"(U6 snRNA 3'-end processing)|go:"GO:1990838"("poly(U)-specific exoribonuclease activity, producing 3' uridine cyclic phosphate ends")|interpro:IPR027521|rcsb pdb:5UQJ	refseq:NP_001137154.1|refseq:NP_065949.1|refseq:XP_016875196.1|dip:DIP-47322N|ensembl:ENSG00000012822(gene)|ensembl:ENST00000550804(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0007165"(signal transduction)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0070016"(armadillo repeat domain binding)|interpro:IPR012852(Coiled-coil transcriptional coactivator-like)|interpro:IPR041611|interpro:IPR041641|mint:Q9P1Z2	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:vJ6GZFlbc3RC9UKZdc4+yyCFQfs559292	rogid:4M9Qyq+7GZ1w2UAN6k0ntGQNTvw9606	intact-crc:E70757D6F33AD81B|rigid:uDRyJNp12uggzE8+eBl83Rl0XIc	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9P1Z2	uniprotkb:P46678	intact:EBI-749920|uniprotkb:B3KVA8|uniprotkb:Q6FI59|uniprotkb:Q71RC3|uniprotkb:Q86WF8|uniprotkb:Q96JU3|uniprotkb:Q9H090|intact:EBI-2558801|ensembl:ENSP00000449960	intact:EBI-19164|uniprotkb:D6W1E0|ensemblfungi:YNL039W	psi-mi:caco1_human(display_long)|uniprotkb:CALCOCO1(gene name)|psi-mi:CALCOCO1(display_short)|uniprotkb:KIAA1536(gene name synonym)|uniprotkb:Calphoglin(gene name synonym)|uniprotkb:Sarcoma antigen NY-SAR-3(gene name synonym)|uniprotkb:Coiled-coil coactivator protein(gene name synonym)|uniprotkb:PP13275(orf name)|uniprotkb:UNQ2436/PRO4996(orf name)	psi-mi:tfc5_yeast(display_long)|uniprotkb:TFIIIB90(gene name synonym)|uniprotkb:BDP1(gene name)|psi-mi:BDP1(display_short)|uniprotkb:TFC5(gene name synonym)|uniprotkb:YNL039W(locus name)|uniprotkb:N2682(orf name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554660|imex:IM-24995-4236	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001137154.1|refseq:NP_065949.1|refseq:XP_016875196.1|dip:DIP-47322N|ensembl:ENSG00000012822(gene)|ensembl:ENST00000550804(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0007165"(signal transduction)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0070016"(armadillo repeat domain binding)|interpro:IPR012852(Coiled-coil transcriptional coactivator-like)|interpro:IPR041611|interpro:IPR041641|mint:Q9P1Z2	sgd:S000004984|ensemblfungi:YNL039W(gene)|ensemblfungi:YNL039W_mRNA(transcript)|go:"GO:0000126"(transcription factor TFIIIB complex)|go:"GO:0000995"(RNA polymerase III general transcription initiation factor activity)|go:"GO:0001112"(DNA-templated transcription open complex formation)|go:"GO:0001156"(TFIIIC-class transcription factor complex binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0070896"(positive regulation of transposon integration)|go:"GO:0070898"(RNA polymerase III preinitiation complex assembly)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017174(Transcription factor IIIB, Bdp1 subunit, fungi)|interpro:IPR039467|rcsb pdb:6CNB|rcsb pdb:6CNC|rcsb pdb:6CND|rcsb pdb:6CNF|rcsb pdb:6EU0|rcsb pdb:6F40|rcsb pdb:6F41|rcsb pdb:6F42|rcsb pdb:6F44|reactome:R-SCE-76061|reactome:R-SCE-76066|refseq:NP_014359.3|dip:DIP-964N|mint:P46678	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:4M9Qyq+7GZ1w2UAN6k0ntGQNTvw9606	rogid:UHI3UvDK3qlouZn4JrhYcxOhr1s559292	intact-crc:DBEED9852FB01648|rigid:jQCvoloeNiBRCXgyf7rudSND1Ws	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q04264	uniprotkb:Q9P1Z2	intact:EBI-13077|uniprotkb:Q04780|uniprotkb:D6VZQ0|ensemblfungi:YMR076C	intact:EBI-749920|uniprotkb:B3KVA8|uniprotkb:Q6FI59|uniprotkb:Q71RC3|uniprotkb:Q86WF8|uniprotkb:Q96JU3|uniprotkb:Q9H090|intact:EBI-2558801|ensembl:ENSP00000449960	psi-mi:pds5_yeast(display_long)|uniprotkb:PDS5(gene name)|psi-mi:PDS5(display_short)|uniprotkb:YMR076C(locus name)|uniprotkb:YM9916.15C(orf name)|uniprotkb:YM9582.01C(orf name)|uniprotkb:Precocious dissociation of sisters protein 5(gene name synonym)	psi-mi:caco1_human(display_long)|uniprotkb:CALCOCO1(gene name)|psi-mi:CALCOCO1(display_short)|uniprotkb:KIAA1536(gene name synonym)|uniprotkb:Calphoglin(gene name synonym)|uniprotkb:Sarcoma antigen NY-SAR-3(gene name synonym)|uniprotkb:Coiled-coil coactivator protein(gene name synonym)|uniprotkb:PP13275(orf name)|uniprotkb:UNQ2436/PRO4996(orf name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554656|imex:IM-24995-4235	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013793.1|sgd:S000004681|mint:Q04264|dip:DIP-6799N|ensemblfungi:YMR076C(gene)|ensemblfungi:YMR076C_mRNA(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0035808"(meiotic recombination initiation complex)|go:"GO:0042138"(meiotic DNA double-strand break formation)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0140588"(chromatin looping)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR032682|interpro:IPR039776|rcsb pdb:5FRP|rcsb pdb:5FRR|rcsb pdb:5FRS|reactome:R-SCE-2468052|reactome:R-SCE-2500257	refseq:NP_001137154.1|refseq:NP_065949.1|refseq:XP_016875196.1|dip:DIP-47322N|ensembl:ENSG00000012822(gene)|ensembl:ENST00000550804(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0007165"(signal transduction)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0070016"(armadillo repeat domain binding)|interpro:IPR012852(Coiled-coil transcriptional coactivator-like)|interpro:IPR041611|interpro:IPR041641|mint:Q9P1Z2	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:JtsuFYTdfc1TRvCvtjuJ8AAHCoU559292	rogid:4M9Qyq+7GZ1w2UAN6k0ntGQNTvw9606	intact-crc:DE570AF918290820|rigid:xsK8GEqbD9RUATwoolwsYbSf/uw	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P25372	uniprotkb:Q9NYB9-2	intact:EBI-19616|uniprotkb:D6VR84|ensemblfungi:YCR083W	intact:EBI-11096309|ensembl:ENSP00000261017	psi-mi:trx3_yeast(display_long)|uniprotkb:TRX3(gene name)|psi-mi:TRX3(display_short)|uniprotkb:YCR83W(orf name)|uniprotkb:YCR083W(locus name)	psi-mi:q9nyb9-2(display_long)|uniprotkb:ABI2(gene name)|psi-mi:ABI2(display_short)|uniprotkb:ARGBPIA(gene name synonym)|uniprotkb:Abelson interactor 2(gene name synonym)|uniprotkb:Abl-binding protein 3(gene name synonym)|uniprotkb:Arg-binding protein 1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554640|imex:IM-24995-4231	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR036249|refseq:NP_010006.1|sgd:S000000679|interpro:IPR017937|interpro:IPR013766(Thioredoxin domain)|rcsb pdb:2OE0|rcsb pdb:2OE1|rcsb pdb:2OE3|ensemblfungi:YCR083W(gene)|ensemblfungi:YCR083W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0015036"(disulfide oxidoreductase activity)|go:"GO:0034599"(cellular response to oxidative stress)|rcsb pdb:5YKW	intact:EBI-743598(isoform-parent)|ensembl:ENSG00000138443(gene)|ensembl:ENST00000261017(transcript)|uniprotkb:Q9NYB9-2(isoform-parent)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:g0xjGf9GvJRl8iv2qoT5tOs7jXI559292	rogid:VNi9aUeavD8+CCi+n1DXS+7mmbs9606	intact-crc:70EDEEACE1615B87|rigid:nwQyVIFS3EIBtCZK24g9kspA1yM	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P09435	uniprotkb:Q9NZL4	intact:EBI-8611|uniprotkb:P18862|uniprotkb:D6VPS7|ensemblfungi:YBL075C	intact:EBI-356763|uniprotkb:O95351|uniprotkb:Q6ZNU5|uniprotkb:B3KQP0|uniprotkb:B4DG11|ensembl:ENSP00000255631|ensembl:ENSP00000398244|ensembl:ENSP00000467574	psi-mi:hsp73_yeast(display_long)|uniprotkb:YBL06.07(orf name)|uniprotkb:YBL0610(orf name)|uniprotkb:YBL075C(locus name)|uniprotkb:SSA3(gene name)|psi-mi:SSA3(display_short)	psi-mi:hpbp1_human(display_long)|uniprotkb:HSPBP1(gene name)|psi-mi:HSPBP1(display_short)|uniprotkb:HSPBP(gene name synonym)|uniprotkb:PP1845(orf name)|uniprotkb:Heat shock protein-binding protein 1(gene name synonym)|uniprotkb:Hsp70-interacting protein 1(gene name synonym)|uniprotkb:Hsp70-binding protein 2(gene name synonym)|uniprotkb:Hsp70-interacting protein 2(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554648|imex:IM-24995-4233	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009478.1|sgd:S000000171|mint:P09435|dip:DIP-2266N|ensemblfungi:YBL075C(gene)|ensemblfungi:YBL075C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129	refseq:NP_001123578.1|refseq:NP_036399.3|ensembl:ENSG00000133265(gene)|ensembl:ENST00000255631(transcript)|ensembl:ENST00000433386(transcript)|ensembl:ENST00000587922(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006457"(protein folding)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013918(Nucleotide exchange factor Fes1)|interpro:IPR016024(Armadillo-type fold)|mint:Q9NZL4|rcsb pdb:1XQR|rcsb pdb:1XQS|refseq:NP_001284529.1|refseq:XP_016882033.1	-	crc64:F4B136759B7D4636	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2018/09/18	rogid:u3ayjvFHnVNMMrDZdrB7NWaGzBg559292	rogid:26Au2GesO5ysT/yhYX/0oOO9Md89606	intact-crc:F90F908593F2C9E8|rigid:dUh2qq010WSAE0IUFY/aCrP3YqM	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9NYB9-2	uniprotkb:P16523	intact:EBI-11096309|ensembl:ENSP00000261017	intact:EBI-10736|ensemblfungi:YNL210W|uniprotkb:D6W0Y0	psi-mi:q9nyb9-2(display_long)|uniprotkb:ABI2(gene name)|psi-mi:ABI2(display_short)|uniprotkb:ARGBPIA(gene name synonym)|uniprotkb:Abelson interactor 2(gene name synonym)|uniprotkb:Abl-binding protein 3(gene name synonym)|uniprotkb:Arg-binding protein 1(gene name synonym)	psi-mi:mer1_yeast(display_long)|uniprotkb:N1330(orf name)|uniprotkb:YNL210W(locus name)|uniprotkb:MER1(gene name)|psi-mi:MER1(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554644|imex:IM-24995-4232	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-743598(isoform-parent)|ensembl:ENSG00000138443(gene)|ensembl:ENST00000261017(transcript)|uniprotkb:Q9NYB9-2(isoform-parent)	ensemblfungi:YNL210W(gene)|ensemblfungi:YNL210W_mRNA(transcript)|go:"GO:0000280"(nuclear division)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005844"(polysome)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:1990446"(U1 snRNP binding)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR036612|refseq:NP_014189.1|sgd:S000005154|dip:DIP-1436N	-	-	crc64:D23EC9B4849D73BA	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:VNi9aUeavD8+CCi+n1DXS+7mmbs9606	rogid:z5sxL8DmpJlmKWc7u/shEOoJkrQ559292	intact-crc:66349FB9E1ACE3EB|rigid:41Yb9vz0z9pMOt+GLAV4Yrjvdx4	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P09435	uniprotkb:Q9NZL4-3	intact:EBI-8611|uniprotkb:P18862|uniprotkb:D6VPS7|ensemblfungi:YBL075C	intact:EBI-11523082	psi-mi:hsp73_yeast(display_long)|uniprotkb:YBL06.07(orf name)|uniprotkb:YBL0610(orf name)|uniprotkb:YBL075C(locus name)|uniprotkb:SSA3(gene name)|psi-mi:SSA3(display_short)	psi-mi:q9nzl4-3(display_long)|uniprotkb:Hsp70-binding protein 2(gene name synonym)|uniprotkb:Hsp70-interacting protein 1(gene name synonym)|uniprotkb:Hsp70-interacting protein 2(gene name synonym)|uniprotkb:PP1845(orf name)|uniprotkb:HSPBP(gene name synonym)|uniprotkb:Heat shock protein-binding protein 1(gene name synonym)|uniprotkb:HSPBP1(gene name)|psi-mi:HSPBP1(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554652|imex:IM-24995-4234	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009478.1|sgd:S000000171|mint:P09435|dip:DIP-2266N|ensemblfungi:YBL075C(gene)|ensemblfungi:YBL075C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129	intact:EBI-356763(isoform-parent)	-	crc64:F4B136759B7D4636	isoform-comment:No experimental confirmation available.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2018/09/18	rogid:u3ayjvFHnVNMMrDZdrB7NWaGzBg559292	rogid:eksiodSyAZ64buylaUz3lcTN4lU9606	intact-crc:420BA1E19A9CE42C|rigid:D5OQrSCWKVj1rcaOah6eGHnz/Hg	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P38340	uniprotkb:Q9P2A4	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-742038|uniprotkb:C9IZN8|ensembl:ENSP00000225941|uniprotkb:Q9H0P6	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:abi3_human(display_long)|uniprotkb:New molecule including SH3(gene name synonym)|uniprotkb:ABI3(gene name)|psi-mi:ABI3(display_short)|uniprotkb:NESH(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554692|imex:IM-24995-4244	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F	refseq:NP_001128658.1|refseq:NP_057512.1|ensembl:ENSG00000108798(gene)|ensembl:ENST00000225941(transcript)|go:"GO:0002357"(defense response to tumor cell)|go:"GO:0005737"(cytoplasm)|go:"GO:0010593"(negative regulation of lamellipodium assembly)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031209"(SCAR complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0051015"(actin filament binding)|go:"GO:0061001"(regulation of dendritic spine morphogenesis)|go:"GO:0099151"(regulation of postsynaptic density assembly)|go:"GO:1900028"(negative regulation of ruffle assembly)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|go:"GO:2000249"(regulation of actin cytoskeleton reorganization)|go:"GO:2000774"(positive regulation of cellular senescence)|interpro:IPR001452(Src homology-3)|interpro:IPR012849(Abl-interactor, homeo-domain homologous region)|interpro:IPR028455|interpro:IPR028457|interpro:IPR036028|mint:Q9P2A4	-	crc64:66699F37B0013088	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:VAjz40ulLa5L+GmfL7ia5wTDND49606	intact-crc:565570FB95269B43|rigid:ZzmrJLOHIzqscfc6FvWmLPw50F8	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9P2A4	uniprotkb:O14468	intact:EBI-742038|uniprotkb:C9IZN8|ensembl:ENSP00000225941|uniprotkb:Q9H0P6	intact:EBI-2343965|uniprotkb:D6W304|ensemblfungi:YOR304C-A	psi-mi:abi3_human(display_long)|uniprotkb:New molecule including SH3(gene name synonym)|uniprotkb:ABI3(gene name)|psi-mi:ABI3(display_short)|uniprotkb:NESH(gene name synonym)	psi-mi:yo304_yeast(display_long)|uniprotkb:YOR304C-A(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554688|imex:IM-24995-4243	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001128658.1|refseq:NP_057512.1|ensembl:ENSG00000108798(gene)|ensembl:ENST00000225941(transcript)|go:"GO:0002357"(defense response to tumor cell)|go:"GO:0005737"(cytoplasm)|go:"GO:0010593"(negative regulation of lamellipodium assembly)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031209"(SCAR complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0051015"(actin filament binding)|go:"GO:0061001"(regulation of dendritic spine morphogenesis)|go:"GO:0099151"(regulation of postsynaptic density assembly)|go:"GO:1900028"(negative regulation of ruffle assembly)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|go:"GO:2000249"(regulation of actin cytoskeleton reorganization)|go:"GO:2000774"(positive regulation of cellular senescence)|interpro:IPR001452(Src homology-3)|interpro:IPR012849(Abl-interactor, homeo-domain homologous region)|interpro:IPR028455|interpro:IPR028457|interpro:IPR036028|mint:Q9P2A4	sgd:S000005830|refseq:NP_014949.3|mint:O14468|ensemblfungi:YOR304C-A(gene)|ensemblfungi:YOR304C-A_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005933"(cellular bud)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0043332"(mating projection tip)|go:"GO:0051017"(actin filament bundle assembly)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:VAjz40ulLa5L+GmfL7ia5wTDND49606	rogid:+5KU/P9FeqlhSbGhpYJ1V6DqQNg559292	intact-crc:1450E553FDF7DA40|rigid:SQBbXoZnK7LCw4iWRo2H61tTfMM	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P39682	uniprotkb:Q9P2A4	intact:EBI-612|uniprotkb:D6VZC9|uniprotkb:E9P8Z1|ensemblfungi:YML046W	intact:EBI-742038|uniprotkb:C9IZN8|ensembl:ENSP00000225941|uniprotkb:Q9H0P6	psi-mi:prp39_yeast(display_long)|uniprotkb:YM9827.06(orf name)|uniprotkb:YML046W(locus name)|uniprotkb:PRP39(gene name)|psi-mi:PRP39(display_short)	psi-mi:abi3_human(display_long)|uniprotkb:New molecule including SH3(gene name synonym)|uniprotkb:ABI3(gene name)|psi-mi:ABI3(display_short)|uniprotkb:NESH(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554684|imex:IM-24995-4242	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013667.1|sgd:S000004509|dip:DIP-812N|mint:P39682|ensemblfungi:YML046W(gene)|ensemblfungi:YML046W_mRNA(transcript)|go:"GO:0000243"(commitment complex)|go:"GO:0000395"(mRNA 5'-splice site recognition)|go:"GO:0005685"(U1 snRNP)|go:"GO:0071004"(U2-type prespliceosome)|interpro:IPR003107(RNA-processing protein, HAT helix)|interpro:IPR011990(Tetratricopeptide-like helical)|rcsb pdb:5ZWN|rcsb pdb:6G90|rcsb pdb:6N7P|rcsb pdb:6N7R|rcsb pdb:6N7X	refseq:NP_001128658.1|refseq:NP_057512.1|ensembl:ENSG00000108798(gene)|ensembl:ENST00000225941(transcript)|go:"GO:0002357"(defense response to tumor cell)|go:"GO:0005737"(cytoplasm)|go:"GO:0010593"(negative regulation of lamellipodium assembly)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031209"(SCAR complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0051015"(actin filament binding)|go:"GO:0061001"(regulation of dendritic spine morphogenesis)|go:"GO:0099151"(regulation of postsynaptic density assembly)|go:"GO:1900028"(negative regulation of ruffle assembly)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|go:"GO:2000249"(regulation of actin cytoskeleton reorganization)|go:"GO:2000774"(positive regulation of cellular senescence)|interpro:IPR001452(Src homology-3)|interpro:IPR012849(Abl-interactor, homeo-domain homologous region)|interpro:IPR028455|interpro:IPR028457|interpro:IPR036028|mint:Q9P2A4	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:urVLzQFKnYT1bYOs3yRd9dd7lMk559292	rogid:VAjz40ulLa5L+GmfL7ia5wTDND49606	intact-crc:7F37C62DBA23219B|rigid:UCLOxnRR+nFmXuBy6ddfW7m0mDc	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q12259	uniprotkb:Q9P209	intact:EBI-30776|uniprotkb:D6VYA8|ensemblfungi:YLR108C	intact:EBI-739498|uniprotkb:Q9BV03|uniprotkb:Q9BWM3|uniprotkb:Q9NVR4|uniprotkb:B4DR26|ensembl:ENSP00000264935	psi-mi:yl108_yeast(display_long)|uniprotkb:L2913(orf name)|uniprotkb:YLR108C(locus name)	psi-mi:cep72_human(display_long)|uniprotkb:CEP72(gene name)|psi-mi:CEP72(display_short)|uniprotkb:KIAA1519(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554668|imex:IM-24995-4238	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013209.1|sgd:S000004098|dip:DIP-4075N|ensemblfungi:YLR108C(gene)|ensemblfungi:YLR108C_mRNA(transcript)|go:"GO:0005634"(nucleus)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)	refseq:NP_060610.2|ensembl:ENSG00000112877(gene)|ensembl:ENST00000264935(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007051"(spindle organization)|go:"GO:0007099"(centriole replication)|go:"GO:0033566"(gamma-tubulin complex localization)|go:"GO:0034451"(centriolar satellite)|go:"GO:1904779"(regulation of protein localization to centrosome)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR003603(U2A'/phosphoprotein 32 family A, C-terminal)|interpro:IPR032675|interpro:IPR040146|mint:Q9P209|reactome:R-HSA-2565942|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|refseq:XP_011512365.1|dip:DIP-54272N	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:CzknxXhhvgMp3J0/oi197EgZ05U559292	rogid:c00WdgE2iudiQUz3kXNZL5d0nuQ9606	intact-crc:13DB4F85B4942F27|rigid:ONT4emawE0Sz85EvUQeNZ2+b7Hg	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P32474	uniprotkb:Q9P286	intact:EBI-2343998|uniprotkb:D6VTD9|uniprotkb:E9P901|ensemblfungi:YDR518W	intact:EBI-741896|ensembl:ENSP00000322957|ensembl:ENSP00000367679|ensembl:ENSP00000367686|intact:EBI-1051061|uniprotkb:A8K5T6|uniprotkb:D3DW14|uniprotkb:Q5W115|uniprotkb:Q8TB93|uniprotkb:Q9BX09|uniprotkb:Q9ULF6	psi-mi:eug1_yeast(display_long)|uniprotkb:EUG1(gene name)|psi-mi:EUG1(display_short)|uniprotkb:Endoplasmic reticulum protein EUG1(gene name synonym)|uniprotkb:D9719.23(orf name)|uniprotkb:YDR518W(locus name)	psi-mi:pak5_human(display_long)|uniprotkb:PAK5(gene name)|psi-mi:PAK5(display_short)|uniprotkb:KIAA1264(gene name synonym)|uniprotkb:PAK7(gene name synonym)|uniprotkb:p21-activated kinase 5(gene name synonym)|uniprotkb:p21-activated kinase 7(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554676|imex:IM-24995-4240	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010806.1|sgd:S000002926|interpro:IPR005792(Protein disulphide isomerase)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR036249|ensemblfungi:YDR518W(gene)|ensemblfungi:YDR518W_mRNA(transcript)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006457"(protein folding)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0019153"("protein-disulfide reductase (glutathione) activity")|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0051082"(unfolded protein binding)	ensembl:ENSG00000101349(gene)|go:"GO:0045202"(synapse)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR028754|interpro:IPR033923|interpro:IPR036936|rcsb pdb:2F57|reactome:R-HSA-428540|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013405|reactome:R-HSA-9013407|go:"GO:0043408"(regulation of MAPK cascade)|ensembl:ENST00000353224(transcript)|ensembl:ENST00000378423(transcript)|ensembl:ENST00000378429(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007165"(signal transduction)|go:"GO:0007612"(learning)|go:"GO:0007613"(memory)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016477"(cell migration)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0035556"(intracellular signal transduction)|refseq:NP_065074.1|refseq:NP_817127.1|refseq:XP_016883449.1|refseq:XP_016883450.1|refseq:XP_016883451.1|refseq:XP_016883452.1|refseq:XP_016883453.1|refseq:XP_016883454.1	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2017/06/28	rogid:HGjMgN6bwOoRQeGJ4/p/rM1ay1g559292	rogid:xxNDwmHn4jv8toBmviGjFwBU32E9606	intact-crc:A647C3115ED92440|rigid:5tzMT9/FZi944PcoXr1XnJ9v9mA	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9P286	uniprotkb:P47041	intact:EBI-741896|ensembl:ENSP00000322957|ensembl:ENSP00000367679|ensembl:ENSP00000367686|intact:EBI-1051061|uniprotkb:A8K5T6|uniprotkb:D3DW14|uniprotkb:Q5W115|uniprotkb:Q8TB93|uniprotkb:Q9BX09|uniprotkb:Q9ULF6	intact:EBI-25889|uniprotkb:D6VWC4|ensemblfungi:YJL058C	psi-mi:pak5_human(display_long)|uniprotkb:PAK5(gene name)|psi-mi:PAK5(display_short)|uniprotkb:KIAA1264(gene name synonym)|uniprotkb:PAK7(gene name synonym)|uniprotkb:p21-activated kinase 5(gene name synonym)|uniprotkb:p21-activated kinase 7(gene name synonym)	psi-mi:bit61_yeast(display_long)|uniprotkb:YJL058C(locus name)|uniprotkb:J1141(orf name)|uniprotkb:61 kDa binding partner of TOR2 protein(gene name synonym)|uniprotkb:BIT61(gene name)|psi-mi:BIT61(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554672|imex:IM-24995-4239	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000101349(gene)|go:"GO:0045202"(synapse)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR028754|interpro:IPR033923|interpro:IPR036936|rcsb pdb:2F57|reactome:R-HSA-428540|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013405|reactome:R-HSA-9013407|go:"GO:0043408"(regulation of MAPK cascade)|ensembl:ENST00000353224(transcript)|ensembl:ENST00000378423(transcript)|ensembl:ENST00000378429(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007165"(signal transduction)|go:"GO:0007612"(learning)|go:"GO:0007613"(memory)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016477"(cell migration)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0035556"(intracellular signal transduction)|refseq:NP_065074.1|refseq:NP_817127.1|refseq:XP_016883449.1|refseq:XP_016883450.1|refseq:XP_016883451.1|refseq:XP_016883452.1|refseq:XP_016883453.1|refseq:XP_016883454.1	refseq:NP_012477.1|sgd:S000003594|dip:DIP-1444N|reactome:R-SCE-1257604|reactome:R-SCE-389357|reactome:R-SCE-5218920|ensemblfungi:YJL058C(gene)|ensemblfungi:YJL058C_mRNA(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005737"(cytoplasm)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0031932"(TORC2 complex)|go:"GO:0038203"(TORC2 signaling)|go:"GO:0071944"(cell periphery)|interpro:IPR013745(HbrB-like)|reactome:R-SCE-6804757	-	-	crc64:99F0F96840311F4B	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2017/06/28	rogid:xxNDwmHn4jv8toBmviGjFwBU32E9606	rogid:H+zcKwbWL90wsmvD9TfWYmEbRwM559292	intact-crc:4546D49E859836E4|rigid:WEa7pLLKEqJ07g0CUxe3Q2BVVu0	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9P286	uniprotkb:P32502	intact:EBI-741896|ensembl:ENSP00000322957|ensembl:ENSP00000367679|ensembl:ENSP00000367686|intact:EBI-1051061|uniprotkb:A8K5T6|uniprotkb:D3DW14|uniprotkb:Q5W115|uniprotkb:Q8TB93|uniprotkb:Q9BX09|uniprotkb:Q9ULF6	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:pak5_human(display_long)|uniprotkb:PAK5(gene name)|psi-mi:PAK5(display_short)|uniprotkb:KIAA1264(gene name synonym)|uniprotkb:PAK7(gene name synonym)|uniprotkb:p21-activated kinase 5(gene name synonym)|uniprotkb:p21-activated kinase 7(gene name synonym)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554680|imex:IM-24995-4241	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000101349(gene)|go:"GO:0045202"(synapse)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR028754|interpro:IPR033923|interpro:IPR036936|rcsb pdb:2F57|reactome:R-HSA-428540|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013405|reactome:R-HSA-9013407|go:"GO:0043408"(regulation of MAPK cascade)|ensembl:ENST00000353224(transcript)|ensembl:ENST00000378423(transcript)|ensembl:ENST00000378429(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007165"(signal transduction)|go:"GO:0007612"(learning)|go:"GO:0007613"(memory)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016477"(cell migration)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0035556"(intracellular signal transduction)|refseq:NP_065074.1|refseq:NP_817127.1|refseq:XP_016883449.1|refseq:XP_016883450.1|refseq:XP_016883451.1|refseq:XP_016883452.1|refseq:XP_016883453.1|refseq:XP_016883454.1	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731	-	-	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2017/06/28	rogid:xxNDwmHn4jv8toBmviGjFwBU32E9606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:69FF174217E8B081|rigid:b6e7eWLgobYY9K2Dq57PbP/v+1I	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9UFD9	uniprotkb:P23059	intact:EBI-10182375|uniprotkb:Q9UFQ5|uniprotkb:Q8IYP7|uniprotkb:Q9BY94|intact:EBI-28984856|ensembl:ENSP00000483386	intact:EBI-10950|ensemblfungi:YCR020C-A|uniprotkb:D6VR29	psi-mi:rim3a_human(display_long)|uniprotkb:RIMBP3(gene name)|psi-mi:RIMBP3(display_short)|uniprotkb:KIAA1666(gene name synonym)|uniprotkb:RIMBP3A(gene name synonym)|uniprotkb:RIMS-binding protein 3.1(gene name synonym)	psi-mi:naa38_yeast(display_long)|uniprotkb:MAK31(gene name)|psi-mi:MAK31(display_short)|uniprotkb:YCR020C-A(locus name)|uniprotkb:YCR20C-A(orf name)|uniprotkb:L-A virus GAG protein N-acetyltransferase subunit MAK31(gene name synonym)|uniprotkb:Maintenance of killer protein 31(gene name synonym)|uniprotkb:NAA38(gene name synonym)|uniprotkb:N-terminal acetyltransferase C complex subunit MAK31(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554712|imex:IM-24995-4249	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_056487.1|ensembl:ENSP00000483386|ensembl:ENSG00000275793(gene)|ensembl:ENST00000619918(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007286"(spermatid development)|go:"GO:0009566"(fertilization)|go:"GO:0030156"(benzodiazepine receptor binding)|go:"GO:0045202"(synapse)|interpro:IPR001452(Src homology-3)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR035515|interpro:IPR036028|interpro:IPR036116|interpro:IPR040325|rcsb pdb:2EGE	ensemblfungi:YCR020C-A(gene)|ensemblfungi:YCR020C-A_mRNA(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005688"(U6 snRNP)|go:"GO:0005829"(cytosol)|go:"GO:0006474"(N-terminal protein amino acid acetylation)|go:"GO:0016070"(RNA metabolic process)|go:"GO:0031417"(NatC complex)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071011"(precatalytic spliceosome)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR034110|rcsb pdb:6YGA|rcsb pdb:6YGB|rcsb pdb:6YGC|rcsb pdb:6YGD|refseq:NP_009948.1|sgd:S000000614|mint:P23059|dip:DIP-1429N	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:iw34Gee4nqAH3pqUfCgQ6Jj++AA9606	rogid:VUwG0xxj0NeyZKANRYCAgJGuqs8559292	intact-crc:974498A1B0E01515|rigid:zNTOeTjSl+BVSEzL3VF/E9J4h2o	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P32502	uniprotkb:Q9UDV6	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	intact:EBI-1640204|uniprotkb:Q13396|uniprotkb:Q8N664|uniprotkb:B2RCF4|ensembl:ENSP00000338572	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:zn212_human(display_long)|uniprotkb:ZNF212(gene name)|psi-mi:ZNF212(display_short)|uniprotkb:ZNFC150(gene name synonym)|uniprotkb:Zinc finger protein C2H2-150(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554708|imex:IM-24995-4248	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731	refseq:NP_036388.2|ensembl:ENSG00000170260(gene)|ensembl:ENST00000335870(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR022137|interpro:IPR036051|interpro:IPR036236|mint:Q9UDV6|reactome:R-HSA-212436	-	crc64:A5409FAF1594854C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	rogid:jZtScr5t/MR83+d1tdA9OiP4JCA9606	intact-crc:918685DF3C96AFCB|rigid:hz8jvORgxHnLSOF79Y5sMHeFAbc	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9P2K3-2	uniprotkb:P33297	intact:EBI-1504830|ensembl:ENSP00000355973	intact:EBI-13920|uniprotkb:D6W2H6|ensemblfungi:YOR117W	psi-mi:q9p2k3-2(display_long)|uniprotkb:RCOR3(gene name)|psi-mi:RCOR3(display_short)|uniprotkb:KIAA1343(gene name synonym)	psi-mi:prs6a_yeast(display_long)|uniprotkb:RPT5(gene name)|psi-mi:RPT5(display_short)|uniprotkb:YTA1(gene name synonym)|uniprotkb:YOR117W(locus name)|uniprotkb:O3258(orf name)|uniprotkb:YOR3258W(orf name)|uniprotkb:Tat-binding protein homolog 1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554696|imex:IM-24995-4245	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000117625(gene)|ensembl:ENST00000367006(transcript)|intact:EBI-743428(isoform-parent)|uniprotkb:Q9P2K3-2(isoform-parent)	sgd:S000005643|rcsb pdb:3WHL|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MP9|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|rcsb pdb:3WHK|reactome:R-SCE-5689880|reactome:R-SCE-6798695|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|ensemblfungi:YOR117W(gene)|ensemblfungi:YOR117W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0070682"(proteasome regulatory particle assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035254|interpro:IPR041569|rcsb pdb:3JCO|rcsb pdb:3JCP|refseq:NP_014760.3|mint:P33297|dip:DIP-1590N	-	isoform-comment:No experimental confirmation available.	crc64:C215422033FCE830	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:RU9KkQB+JnxYVfG5IlAeNKnVFjw9606	rogid:jsQE3SjBA0ZZcysuLgFe/5M6pOc559292	intact-crc:9F1C6DF70841F1AF|rigid:KGMSSmrer4j3RPiU5j612Dn4HRc	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9UDV6	uniprotkb:P38340	intact:EBI-1640204|uniprotkb:Q13396|uniprotkb:Q8N664|uniprotkb:B2RCF4|ensembl:ENSP00000338572	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:zn212_human(display_long)|uniprotkb:ZNF212(gene name)|psi-mi:ZNF212(display_short)|uniprotkb:ZNFC150(gene name synonym)|uniprotkb:Zinc finger protein C2H2-150(gene name synonym)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554700|imex:IM-24995-4246	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_036388.2|ensembl:ENSG00000170260(gene)|ensembl:ENST00000335870(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR022137|interpro:IPR036051|interpro:IPR036236|mint:Q9UDV6|reactome:R-HSA-212436	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F	-	-	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:jZtScr5t/MR83+d1tdA9OiP4JCA9606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:AD425D457AC51C58|rigid:qXq1mnyZehMkMSTEz8juyKSjq8E	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P28004	uniprotkb:Q9UDV6	intact:EBI-20640|uniprotkb:D6VPI6|ensemblfungi:YAL032C	intact:EBI-1640204|uniprotkb:Q13396|uniprotkb:Q8N664|uniprotkb:B2RCF4|ensembl:ENSP00000338572	psi-mi:prp45_yeast(display_long)|uniprotkb:YAL032C(locus name)|uniprotkb:PRP45(gene name)|psi-mi:PRP45(display_short)|uniprotkb:FUN20(gene name synonym)	psi-mi:zn212_human(display_long)|uniprotkb:ZNF212(gene name)|psi-mi:ZNF212(display_short)|uniprotkb:ZNFC150(gene name synonym)|uniprotkb:Zinc finger protein C2H2-150(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554704|imex:IM-24995-4247	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009370.1|sgd:S000000030|ensemblfungi:YAL032C(gene)|ensemblfungi:YAL032C_mRNA(transcript)|go:"GO:0000350"(generation of catalytic spliceosome for second transesterification step)|go:"GO:0005634"(nucleus)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|interpro:IPR004015(SKIP/SNW)|interpro:IPR017862|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|dip:DIP-2774N|mint:P28004	refseq:NP_036388.2|ensembl:ENSG00000170260(gene)|ensembl:ENST00000335870(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR022137|interpro:IPR036051|interpro:IPR036236|mint:Q9UDV6|reactome:R-HSA-212436	-	crc64:FE5A724186D7FE84	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:qoHF1UsO3k+JOTOfigSuy2P84/k559292	rogid:jZtScr5t/MR83+d1tdA9OiP4JCA9606	intact-crc:E0FBF664812581ED|rigid:JZrk/DQKgLpkDiy4/hqJoGL3uvo	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q01976	uniprotkb:Q9UGJ1-2	intact:EBI-2344265|uniprotkb:D6VQB0|ensemblfungi:YBR111C	intact:EBI-10964469|ensembl:ENSP00000456648	psi-mi:adpp_yeast(display_long)|uniprotkb:YSA1(gene name)|psi-mi:YSA1(display_short)|uniprotkb:ADP-ribose diphosphatase(gene name synonym)|uniprotkb:Adenosine diphosphoribose pyrophosphatase(gene name synonym)|uniprotkb:ADP-ribose phosphohydrolase(gene name synonym)|uniprotkb:YBR0907(orf name)|uniprotkb:YBR111C(locus name)	psi-mi:q9ugj1-2(display_long)|uniprotkb:TUBGCP4(gene name)|psi-mi:TUBGCP4(display_short)|uniprotkb:76P(gene name synonym)|uniprotkb:GCP4(gene name synonym)|uniprotkb:Gamma-ring complex protein 76 kDa(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554732|imex:IM-24995-4254	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009669.1|sgd:S000000315|interpro:IPR020084|interpro:IPR000086(NUDIX hydrolase, core)|interpro:IPR015797(NUDIX)|reactome:R-SCE-2393930|ensemblfungi:YBR111C(gene)|ensemblfungi:YBR111C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006753"(nucleoside phosphate metabolic process)|go:"GO:0019693"(ribose phosphate metabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0047631"(ADP-ribose diphosphatase activity)	intact:EBI-1052544(isoform-parent)|ensembl:ENSG00000137822(gene)|ensembl:ENST00000564079(transcript)|uniprotkb:Q9UGJ1-2(isoform-parent)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:tpdVT9ttt/pL+UevSr0zW+rfyIc559292	rogid:+lfeIRS3N2OU1+y84kUyKY7ePNA9606	intact-crc:12F03E34B787282C|rigid:Nl6vjWQsboG3a+WfLlabYcKtJaI	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9UGJ1-2	uniprotkb:P18961	intact:EBI-10964469|ensembl:ENSP00000456648	intact:EBI-29484|uniprotkb:D6VZS6|ensemblfungi:YMR104C	psi-mi:q9ugj1-2(display_long)|uniprotkb:TUBGCP4(gene name)|psi-mi:TUBGCP4(display_short)|uniprotkb:76P(gene name synonym)|uniprotkb:GCP4(gene name synonym)|uniprotkb:Gamma-ring complex protein 76 kDa(gene name synonym)	psi-mi:ypk2_yeast(display_long)|uniprotkb:YPK2(gene name)|psi-mi:YPK2(display_short)|uniprotkb:YKR2(gene name synonym)|uniprotkb:YMR104C(locus name)|uniprotkb:YM9718.03C(orf name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554728|imex:IM-24995-4253	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-1052544(isoform-parent)|ensembl:ENSG00000137822(gene)|ensembl:ENST00000564079(transcript)|uniprotkb:Q9UGJ1-2(isoform-parent)	refseq:NP_013822.1|sgd:S000004710|dip:DIP-4438N|mint:P18961|ensemblfungi:YMR104C(gene)|ensemblfungi:YMR104C_mRNA(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0060237"(regulation of fungal-type cell wall organization)|go:"GO:0070941"(eisosome assembly)|go:"GO:0071555"(cell wall organization)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892	-	-	crc64:E1FAB0295386A113	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:+lfeIRS3N2OU1+y84kUyKY7ePNA9606	rogid:wDHCJlSmOMy9MWExwxHzLA4+dO0559292	intact-crc:3BE69682BAA0BBC3|rigid:ipJEgY3MjfpnuYhhjgXoypki4dk	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P31384	uniprotkb:Q9UFF9	intact:EBI-4396|uniprotkb:D6VPJ7|ensemblfungi:YAL021C	intact:EBI-742299|uniprotkb:O95709|uniprotkb:Q7Z521|uniprotkb:Q9H6Y1|uniprotkb:D3DQI8|uniprotkb:B2RAR8|intact:EBI-10979182|uniprotkb:B0AZS3|uniprotkb:B7Z8R1|ensembl:ENSP00000285896|ensembl:ENSP00000384747|ensembl:ENSP00000430493	psi-mi:ccr4_yeast(display_long)|uniprotkb:CCR4(gene name)|psi-mi:CCR4(display_short)|uniprotkb:Carbon catabolite repressor protein 4(gene name synonym)|uniprotkb:Cytoplasmic deadenylase(gene name synonym)|uniprotkb:Glucose-repressible alcohol dehydrogenase transcriptional effector(gene name synonym)|uniprotkb:FUN27(orf name)|uniprotkb:YAL021C(locus name)	psi-mi:cnot8_human(display_long)|uniprotkb:CNOT8(gene name)|psi-mi:CNOT8(display_short)|uniprotkb:CALIF(gene name synonym)|uniprotkb:POP2(gene name synonym)|uniprotkb:CCR4-associated factor 8(gene name synonym)|uniprotkb:CAF1-like protein(gene name synonym)|uniprotkb:CAF2(gene name synonym)|uniprotkb:Caf1b(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554724|imex:IM-24995-4252	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009381.1|sgd:S000000019|dip:DIP-2522N|mint:P31384|ensemblfungi:YAL021C(gene)|ensemblfungi:YAL021C_mRNA(transcript)|go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0004535"("poly(A)-specific ribonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0007089"(traversing start control point of mitotic cell cycle)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0046872"(metal ion binding)|go:"GO:0048478"(replication fork protection)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR005135(Endonuclease/exonuclease/phosphatase)|interpro:IPR025875|interpro:IPR032675|interpro:IPR036691|rcsb pdb:4B8C	refseq:NP_004770.4|refseq:XP_005268584.1|refseq:NP_001288002.1|refseq:NP_001288003.1|refseq:NP_001288004.1|refseq:NP_001288006.1|refseq:NP_001288009.1|refseq:NP_001288011.1|refseq:NP_001288012.1|refseq:NP_001288015.1|refseq:XP_011536008.1|refseq:XP_011536010.1|refseq:XP_016865537.1|refseq:XP_016865538.1|refseq:XP_016865539.1|refseq:XP_016865540.1|refseq:XP_016865541.1|refseq:XP_016865542.1|refseq:XP_016865543.1|refseq:XP_016865544.1|refseq:XP_016865545.1|refseq:XP_016865546.1|ensembl:ENSG00000155508(gene)|ensembl:ENST00000285896(transcript)|ensembl:ENST00000403027(transcript)|ensembl:ENST00000517876(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0004535"("poly(A)-specific ribonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0035195"(gene silencing by miRNA)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0046872"(metal ion binding)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|interpro:IPR006941(Ribonuclease CAF1)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR027212|interpro:IPR036397|interpro:IPR039637|mint:Q9UFF9|reactome:R-HSA-429947|reactome:R-HSA-6804115|dip:DIP-29084N	-	crc64:5CDB2E8FEDDBEF6F	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:f5gxp32WdxKuHQnE8O9/EhhA3Gw559292	rogid:pjaQYzYBGJWC7z5R5s8Te+v2sRA9606	intact-crc:8EEEAC08A8E946F3|rigid:gFrxQ5V6bJZQ9MZJK/RYIsyvq/U	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P47041	uniprotkb:Q9UFD9	intact:EBI-25889|uniprotkb:D6VWC4|ensemblfungi:YJL058C	intact:EBI-10182375|uniprotkb:Q9UFQ5|uniprotkb:Q8IYP7|uniprotkb:Q9BY94|intact:EBI-28984856|ensembl:ENSP00000483386	psi-mi:bit61_yeast(display_long)|uniprotkb:YJL058C(locus name)|uniprotkb:J1141(orf name)|uniprotkb:61 kDa binding partner of TOR2 protein(gene name synonym)|uniprotkb:BIT61(gene name)|psi-mi:BIT61(display_short)	psi-mi:rim3a_human(display_long)|uniprotkb:RIMBP3(gene name)|psi-mi:RIMBP3(display_short)|uniprotkb:KIAA1666(gene name synonym)|uniprotkb:RIMBP3A(gene name synonym)|uniprotkb:RIMS-binding protein 3.1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554720|imex:IM-24995-4251	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012477.1|sgd:S000003594|dip:DIP-1444N|reactome:R-SCE-1257604|reactome:R-SCE-389357|reactome:R-SCE-5218920|ensemblfungi:YJL058C(gene)|ensemblfungi:YJL058C_mRNA(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005737"(cytoplasm)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0031932"(TORC2 complex)|go:"GO:0038203"(TORC2 signaling)|go:"GO:0071944"(cell periphery)|interpro:IPR013745(HbrB-like)|reactome:R-SCE-6804757	refseq:NP_056487.1|ensembl:ENSP00000483386|ensembl:ENSG00000275793(gene)|ensembl:ENST00000619918(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007286"(spermatid development)|go:"GO:0009566"(fertilization)|go:"GO:0030156"(benzodiazepine receptor binding)|go:"GO:0045202"(synapse)|interpro:IPR001452(Src homology-3)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR035515|interpro:IPR036028|interpro:IPR036116|interpro:IPR040325|rcsb pdb:2EGE	-	crc64:99F0F96840311F4B	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:H+zcKwbWL90wsmvD9TfWYmEbRwM559292	rogid:iw34Gee4nqAH3pqUfCgQ6Jj++AA9606	intact-crc:E7DDA6CBE3D50BD4|rigid:znyYkX0tH6uay7ZGWZwtp67LFKk	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9UFD9	uniprotkb:P42937	intact:EBI-10182375|uniprotkb:Q9UFQ5|uniprotkb:Q8IYP7|uniprotkb:Q9BY94|intact:EBI-28984856|ensembl:ENSP00000483386	intact:EBI-23470|uniprotkb:D6VUY5|ensemblfungi:YGR203W	psi-mi:rim3a_human(display_long)|uniprotkb:RIMBP3(gene name)|psi-mi:RIMBP3(display_short)|uniprotkb:KIAA1666(gene name synonym)|uniprotkb:RIMBP3A(gene name synonym)|uniprotkb:RIMS-binding protein 3.1(gene name synonym)	psi-mi:ych1_yeast(display_long)|uniprotkb:YGR203W(locus name)|uniprotkb:G7731(orf name)|uniprotkb:YCH1(gene name)|psi-mi:YCH1(display_short)|uniprotkb:CDC25 homolog 1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554716|imex:IM-24995-4250	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_056487.1|ensembl:ENSP00000483386|ensembl:ENSG00000275793(gene)|ensembl:ENST00000619918(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007286"(spermatid development)|go:"GO:0009566"(fertilization)|go:"GO:0030156"(benzodiazepine receptor binding)|go:"GO:0045202"(synapse)|interpro:IPR001452(Src homology-3)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR035515|interpro:IPR036028|interpro:IPR036116|interpro:IPR040325|rcsb pdb:2EGE	refseq:NP_011719.1|sgd:S000003435|dip:DIP-885N|ensemblfungi:YGR203W(gene)|ensemblfungi:YGR203W_mRNA(transcript)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0004792"(thiosulfate sulfurtransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016311"(dephosphorylation)|go:"GO:0016791"(phosphatase activity)|interpro:IPR001763(Rhodanese-like)|interpro:IPR036873|rcsb pdb:3F4A|rcsb pdb:3FS5	-	-	crc64:41527DB282CBFF11	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:iw34Gee4nqAH3pqUfCgQ6Jj++AA9606	rogid:p8SYf/V7HMF1NdntyAYkfOBvlPk559292	intact-crc:9320E4C6A4F79670|rigid:9l31IlXMhzvSc+WdrwcdhX/6RaY	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P49955	uniprotkb:Q9UHX1-2	intact:EBI-664|uniprotkb:D6W0B5|ensemblfungi:YMR288W	intact:EBI-11529177|ensembl:ENSP00000322036|ensembl:ENSP00000478495	psi-mi:sf3b1_yeast(display_long)|uniprotkb:YMR288W(locus name)|uniprotkb:YM8021.14(orf name)|uniprotkb:HSH155(gene name)|psi-mi:HSH155(display_short)	psi-mi:q9uhx1-2(display_long)|uniprotkb:PUF60(gene name)|psi-mi:PUF60(display_short)|uniprotkb:"60 kDa poly(U)-binding-splicing factor"(gene name synonym)|uniprotkb:FIR(gene name synonym)|uniprotkb:FUSE-binding protein-interacting repressor(gene name synonym)|uniprotkb:ROBPI(gene name synonym)|uniprotkb:Ro-binding protein 1(gene name synonym)|uniprotkb:SIAHBP1(gene name synonym)|uniprotkb:Siah-binding protein 1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554756|imex:IM-24995-4260	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014015.1|sgd:S000004901|dip:DIP-2628N|mint:P49955|ensemblfungi:YMR288W(gene)|ensemblfungi:YMR288W_mRNA(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005686"(U2 snRNP)|go:"GO:0071004"(U2-type prespliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR038737|rcsb pdb:5GM6|rcsb pdb:5LQW|rcsb pdb:5NRL|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:6G90	intact:EBI-1053259(isoform-parent)|ensembl:ENSG00000179950(gene)|ensembl:ENSG00000274081(gene)|ensembl:ENST00000349157(transcript)|ensembl:ENST00000612237(transcript)|uniprotkb:Q9UHX1-2(isoform-parent)	-	crc64:27D26E4252A788E2	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:t0fwQOOum/AO/xL8vhZdF2EGymo559292	rogid:snVN9Lw5+MP2/aiq4z08ANwvr209606	intact-crc:57B9678A7CE09F11|rigid:+F97wpeDmVKWuj1/V1IUtVEp+iQ	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9UHV2	uniprotkb:P48362	intact:EBI-748601|uniprotkb:Q9BUE7|ensembl:ENSP00000350633	intact:EBI-8304|uniprotkb:D6VUX0|ensemblfungi:YGR187C	psi-mi:srtd1_human(display_long)|uniprotkb:Transcriptional regulator interacting with the PHD-bromodomain 1(gene name synonym)|uniprotkb:CDK4-binding protein p34SEI1(gene name synonym)|uniprotkb:SERTAD1(gene name)|psi-mi:SERTAD1(display_short)|uniprotkb:SEI1(gene name synonym)|uniprotkb:TRIPBR1(gene name synonym)	psi-mi:hgh1_yeast(display_long)|uniprotkb:HGH1(gene name)|psi-mi:HGH1(display_short)|uniprotkb:HMG1/2 protein homolog(gene name synonym)|uniprotkb:G7538(orf name)|uniprotkb:YGR187C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554752|imex:IM-24995-4259	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_037508.2|ensembl:ENSG00000197019(gene)|ensembl:ENST00000357949(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048096"|interpro:IPR009263(SERTA)|mint:Q9UHV2	sgd:S000003419|refseq:NP_011703.3|mint:P48362|dip:DIP-4721N|ensemblfungi:YGR187C(gene)|ensemblfungi:YGR187C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0061770"(translation elongation factor binding)|interpro:IPR007205(Protein of unknown function DUF383)|interpro:IPR007206(Protein of unknown function DUF384)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR039717|rcsb pdb:6HB1|rcsb pdb:6HB2|rcsb pdb:6HB3	-	-	crc64:24D4EFAEBD5D7A48	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:40dvjniwxY/UQiyoVREicctpWe09606	rogid:YQkKPiBqhycG0Z+2lxERBLVdy1w559292	intact-crc:9354C89929A8F117|rigid:kPL182n1L1WDQj5e2ABipEAp9dM	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9UGJ1-2	intact:EBI-11522552	intact:EBI-10964469|ensembl:ENSP00000456648	-	psi-mi:q9ugj1-2(display_long)|uniprotkb:TUBGCP4(gene name)|psi-mi:TUBGCP4(display_short)|uniprotkb:76P(gene name synonym)|uniprotkb:GCP4(gene name synonym)|uniprotkb:Gamma-ring complex protein 76 kDa(gene name synonym)	psi-mi:urh1(display_short)|psi-mi:EBI-11522552(display_long)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554736|imex:IM-24995-4255	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-1052544(isoform-parent)|ensembl:ENSG00000137822(gene)|ensembl:ENST00000564079(transcript)|uniprotkb:Q9UGJ1-2(isoform-parent)	-	-	-	no-uniprot-update:	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:+lfeIRS3N2OU1+y84kUyKY7ePNA9606	rogid:uuys9fg/B71sAw+Tb2BvegAXdp84932	intact-crc:117DB15E86124C46|rigid:00J1gknyAajcVLBEJSsfaooFtGE	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P38182	uniprotkb:Q9UH92-3	intact:EBI-2684|uniprotkb:D6VPS5|ensemblfungi:YBL078C	intact:EBI-8852072|ensembl:ENSP00000416627	psi-mi:atg8_yeast(display_long)|uniprotkb:ATG8(gene name)|psi-mi:ATG8(display_short)|uniprotkb:APG8(gene name synonym)|uniprotkb:AUT7(gene name synonym)|uniprotkb:YBL078C(locus name)|uniprotkb:YBL0732(orf name)|uniprotkb:CVT5(gene name synonym)|uniprotkb:Autophagy-related ubiquitin-like modifier ATG8(gene name synonym)|uniprotkb:Cytoplasm to vacuole targeting protein 5(gene name synonym)	psi-mi:q9uh92-3(display_long)|uniprotkb:MLX(gene name)|psi-mi:MLX(display_short)|uniprotkb:BHLHD13(gene name synonym)|uniprotkb:TCFL4(gene name synonym)|uniprotkb:Class D basic helix-loop-helix protein 13(gene name synonym)|uniprotkb:Max-like bHLHZip protein(gene name synonym)|uniprotkb:Protein BigMax(gene name synonym)|uniprotkb:Transcription factor-like protein 4(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554744|imex:IM-24995-4257	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000000174|refseq:NP_009475.1|dip:DIP-1197N|mint:P38182|ensemblfungi:YBL078C(gene)|ensemblfungi:YBL078C_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006914"(autophagy)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0008429"(phosphatidylethanolamine binding)|go:"GO:0016236"(macroautophagy)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0031386"(protein tag)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0033110"(Cvt vesicle membrane)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0034629"|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|go:"GO:0061025"(membrane fusion)|go:"GO:0061709"(reticulophagy)|go:"GO:0071211"(protein targeting to vacuole involved in autophagy)|go:"GO:0120095"(vacuole-isolation membrane contact site)|go:"GO:1905153"(regulation of membrane invagination)|interpro:IPR004241("Light chain 3 (LC3)")|interpro:IPR029071|rcsb pdb:2KQ7|rcsb pdb:2KWC|rcsb pdb:2LI5|rcsb pdb:2ZPN|rcsb pdb:3RUI|rcsb pdb:3VH3|rcsb pdb:3VH4|rcsb pdb:3VXW|rcsb pdb:5YEC|rcsb pdb:6AAG|rcsb pdb:6WY6|rcsb pdb:7BRN|reactome:R-SCE-1632852|reactome:R-SCE-8854214|reactome:R-SCE-8934903	ensembl:ENSG00000108788(gene)|ensembl:ENST00000435881(transcript)|intact:EBI-741109(isoform-parent)|uniprotkb:Q9UH92-3(isoform-parent)	-	crc64:1246CEFF5A038819	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:UlmpBW3JgdYFHLkZCQeJeb7DpK4559292	rogid:M3gABDaYvwenMrLrp6Tbpl6ZU909606	intact-crc:111AAECB2388B0CC|rigid:EWuh8wGIWzo/TY2TXJgjg7rbuHc	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9UH77	uniprotkb:Q08273	intact:EBI-8524663|uniprotkb:Q9ULU0|uniprotkb:B2RBK7|intact:UNK-6172988|uniprotkb:Q9UH76|uniprotkb:Q9UH75|uniprotkb:Q9Y6V6|ensembl:ENSP00000312397	intact:EBI-31686|uniprotkb:D6W1T5|ensemblfungi:YOL133W	psi-mi:klhl3_human(display_long)|uniprotkb:KLHL3(gene name)|psi-mi:KLHL3(display_short)|uniprotkb:KIAA1129(gene name synonym)	psi-mi:rbx1_yeast(display_long)|uniprotkb:E3 ubiquitin-protein ligase complex SCF subunit HRT1(gene name synonym)|uniprotkb:High level expression reduces Ty3 transposition protein 1(gene name synonym)|uniprotkb:HRT1(gene name)|psi-mi:HRT1(display_short)|uniprotkb:RBX1(gene name synonym)|uniprotkb:ROC1(gene name synonym)|uniprotkb:Regulator of cullins protein 1(gene name synonym)|uniprotkb:YOL133W(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554740|imex:IM-24995-4256	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_059111.2|refseq:NP_001244124.1|refseq:NP_001244123.1|ensembl:ENSG00000146021(gene)|ensembl:ENST00000309755(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0050801"(ion homeostasis)|go:"GO:0061912"(selective autophagy)|go:"GO:0070294"(renal sodium ion absorption)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0072156"(distal tubule morphogenesis)|go:"GO:0097602"(cullin family protein binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR017096(Kelch-like protein, gigaxonin)|interpro:IPR030578|rcsb pdb:4CH9|rcsb pdb:4HXI|rcsb pdb:5NKP|reactome:R-HSA-8951664|reactome:R-HSA-983168	refseq:NP_014508.1|sgd:S000005493|dip:DIP-1373N|mint:Q08273|ensemblfungi:YOL133W(gene)|ensemblfungi:YOL133W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0035361"(Cul8-RING ubiquitin ligase complex)|go:"GO:0051301"(cell division)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097602"(cullin family protein binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR024766|reactome:R-SCE-5696395|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-68949|reactome:R-SCE-8854050|reactome:R-SCE-8951664|reactome:R-SCE-983168	-	comment:mint|comment:homomint|function:Probable substrate-specific adapter of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins	crc64:A9C3193E48CAF881	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:6iZNPY/wNDhLlUWeFLl0FyqtFXM9606	rogid:7LBUfvb6zpWuPkbMDrEAnrMuJj8559292	intact-crc:DFDCA9604DC4C0CD|rigid:stfWFAyIC45liOFdXxuWXPy9o8Y	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P35180	uniprotkb:Q9UHV2	intact:EBI-12522|uniprotkb:D6VUL4|ensemblfungi:YGR082W	intact:EBI-748601|uniprotkb:Q9BUE7|ensembl:ENSP00000350633	psi-mi:tom20_yeast(display_long)|uniprotkb:MOM19(gene name synonym)|uniprotkb:YGR082W(locus name)|uniprotkb:TOM20(gene name)|psi-mi:TOM20(display_short)|uniprotkb:MAS20(gene name synonym)|uniprotkb:Mitochondrial 20 kDa outer membrane protein(gene name synonym)|uniprotkb:Translocase of outer membrane 20 kDa subunit(gene name synonym)|uniprotkb:Protein MAS20(gene name synonym)	psi-mi:srtd1_human(display_long)|uniprotkb:Transcriptional regulator interacting with the PHD-bromodomain 1(gene name synonym)|uniprotkb:CDK4-binding protein p34SEI1(gene name synonym)|uniprotkb:SERTAD1(gene name)|psi-mi:SERTAD1(display_short)|uniprotkb:SEI1(gene name synonym)|uniprotkb:TRIPBR1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554748|imex:IM-24995-4258	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YGR082W(gene)|ensemblfungi:YGR082W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005742"(mitochondrial outer membrane translocase complex)|go:"GO:0016031"(tRNA import into mitochondrion)|go:"GO:0030150"(protein import into mitochondrial matrix)|go:"GO:0030943"(mitochondrion targeting sequence binding)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|interpro:IPR002056(Protein import receptor MAS20)|interpro:IPR023392|refseq:NP_011596.1|sgd:S000003314|dip:DIP-2539N|mint:P35180	refseq:NP_037508.2|ensembl:ENSG00000197019(gene)|ensembl:ENST00000357949(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048096"|interpro:IPR009263(SERTA)|mint:Q9UHV2	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:7U00YLVWcaegWlJEKzGblv6STx4559292	rogid:40dvjniwxY/UQiyoVREicctpWe09606	intact-crc:E82478C264035C3A|rigid:gFB1jmG7TnN9Eb/EoV3Dfz5AHN0	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P39682	uniprotkb:Q9UHX1-5	intact:EBI-612|uniprotkb:D6VZC9|uniprotkb:E9P8Z1|ensemblfungi:YML046W	intact:EBI-11526420|ensembl:ENSP00000395417|ensembl:ENSP00000478209	psi-mi:prp39_yeast(display_long)|uniprotkb:YM9827.06(orf name)|uniprotkb:YML046W(locus name)|uniprotkb:PRP39(gene name)|psi-mi:PRP39(display_short)	psi-mi:q9uhx1-5(display_long)|uniprotkb:PUF60(gene name)|psi-mi:PUF60(display_short)|uniprotkb:"60 kDa poly(U)-binding-splicing factor"(gene name synonym)|uniprotkb:FIR(gene name synonym)|uniprotkb:FUSE-binding protein-interacting repressor(gene name synonym)|uniprotkb:ROBPI(gene name synonym)|uniprotkb:Ro-binding protein 1(gene name synonym)|uniprotkb:SIAHBP1(gene name synonym)|uniprotkb:Siah-binding protein 1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554772|imex:IM-24995-4264	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013667.1|sgd:S000004509|dip:DIP-812N|mint:P39682|ensemblfungi:YML046W(gene)|ensemblfungi:YML046W_mRNA(transcript)|go:"GO:0000243"(commitment complex)|go:"GO:0000395"(mRNA 5'-splice site recognition)|go:"GO:0005685"(U1 snRNP)|go:"GO:0071004"(U2-type prespliceosome)|interpro:IPR003107(RNA-processing protein, HAT helix)|interpro:IPR011990(Tetratricopeptide-like helical)|rcsb pdb:5ZWN|rcsb pdb:6G90|rcsb pdb:6N7P|rcsb pdb:6N7R|rcsb pdb:6N7X	intact:EBI-1053259(isoform-parent)|ensembl:ENSG00000179950(gene)|ensembl:ENSG00000274081(gene)|ensembl:ENST00000456095(transcript)|ensembl:ENST00000620953(transcript)	-	-	isoform-comment:"Contains a glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) at position 14."	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:urVLzQFKnYT1bYOs3yRd9dd7lMk559292	rogid:PSbIU++DIL6ysF0ccd3ZHzeJ5rs9606	intact-crc:F72713FC38B0BC03|rigid:Spa7EzJSdtfwuHn1cV5zMiXBmgs	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9UHX1-5	uniprotkb:P38340	intact:EBI-11526420|ensembl:ENSP00000395417|ensembl:ENSP00000478209	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:q9uhx1-5(display_long)|uniprotkb:PUF60(gene name)|psi-mi:PUF60(display_short)|uniprotkb:"60 kDa poly(U)-binding-splicing factor"(gene name synonym)|uniprotkb:FIR(gene name synonym)|uniprotkb:FUSE-binding protein-interacting repressor(gene name synonym)|uniprotkb:ROBPI(gene name synonym)|uniprotkb:Ro-binding protein 1(gene name synonym)|uniprotkb:SIAHBP1(gene name synonym)|uniprotkb:Siah-binding protein 1(gene name synonym)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554768|imex:IM-24995-4263	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-1053259(isoform-parent)|ensembl:ENSG00000179950(gene)|ensembl:ENSG00000274081(gene)|ensembl:ENST00000456095(transcript)|ensembl:ENST00000620953(transcript)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F	-	isoform-comment:"Contains a glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) at position 14."	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:PSbIU++DIL6ysF0ccd3ZHzeJ5rs9606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:E52D1D394AE18FEA|rigid:arMDTNRejdWEm+w41YUmN6muyD8	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P32502	uniprotkb:Q9UHX1-5	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	intact:EBI-11526420|ensembl:ENSP00000395417|ensembl:ENSP00000478209	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:q9uhx1-5(display_long)|uniprotkb:PUF60(gene name)|psi-mi:PUF60(display_short)|uniprotkb:"60 kDa poly(U)-binding-splicing factor"(gene name synonym)|uniprotkb:FIR(gene name synonym)|uniprotkb:FUSE-binding protein-interacting repressor(gene name synonym)|uniprotkb:ROBPI(gene name synonym)|uniprotkb:Ro-binding protein 1(gene name synonym)|uniprotkb:SIAHBP1(gene name synonym)|uniprotkb:Siah-binding protein 1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554776|imex:IM-24995-4265	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731	intact:EBI-1053259(isoform-parent)|ensembl:ENSG00000179950(gene)|ensembl:ENSG00000274081(gene)|ensembl:ENST00000456095(transcript)|ensembl:ENST00000620953(transcript)	-	crc64:A5409FAF1594854C	isoform-comment:"Contains a glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) at position 14."	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	rogid:PSbIU++DIL6ysF0ccd3ZHzeJ5rs9606	intact-crc:0A6F3A7DF0D27D20|rigid:PzoP+QJrcfD3B9lJsjj4mbQViMs	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9UHX1-2	uniprotkb:P38340	intact:EBI-11529177|ensembl:ENSP00000322036|ensembl:ENSP00000478495	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:q9uhx1-2(display_long)|uniprotkb:PUF60(gene name)|psi-mi:PUF60(display_short)|uniprotkb:"60 kDa poly(U)-binding-splicing factor"(gene name synonym)|uniprotkb:FIR(gene name synonym)|uniprotkb:FUSE-binding protein-interacting repressor(gene name synonym)|uniprotkb:ROBPI(gene name synonym)|uniprotkb:Ro-binding protein 1(gene name synonym)|uniprotkb:SIAHBP1(gene name synonym)|uniprotkb:Siah-binding protein 1(gene name synonym)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554760|imex:IM-24995-4261	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-1053259(isoform-parent)|ensembl:ENSG00000179950(gene)|ensembl:ENSG00000274081(gene)|ensembl:ENST00000349157(transcript)|ensembl:ENST00000612237(transcript)|uniprotkb:Q9UHX1-2(isoform-parent)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F	-	-	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:snVN9Lw5+MP2/aiq4z08ANwvr209606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:2C82D6597A3806D2|rigid:9yjNEVIDBi5WlCsKOQdzJS9UL3I	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9UHX1-5	uniprotkb:P49955	intact:EBI-11526420|ensembl:ENSP00000395417|ensembl:ENSP00000478209	intact:EBI-664|uniprotkb:D6W0B5|ensemblfungi:YMR288W	psi-mi:q9uhx1-5(display_long)|uniprotkb:PUF60(gene name)|psi-mi:PUF60(display_short)|uniprotkb:"60 kDa poly(U)-binding-splicing factor"(gene name synonym)|uniprotkb:FIR(gene name synonym)|uniprotkb:FUSE-binding protein-interacting repressor(gene name synonym)|uniprotkb:ROBPI(gene name synonym)|uniprotkb:Ro-binding protein 1(gene name synonym)|uniprotkb:SIAHBP1(gene name synonym)|uniprotkb:Siah-binding protein 1(gene name synonym)	psi-mi:sf3b1_yeast(display_long)|uniprotkb:YMR288W(locus name)|uniprotkb:YM8021.14(orf name)|uniprotkb:HSH155(gene name)|psi-mi:HSH155(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554780|imex:IM-24995-4266	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-1053259(isoform-parent)|ensembl:ENSG00000179950(gene)|ensembl:ENSG00000274081(gene)|ensembl:ENST00000456095(transcript)|ensembl:ENST00000620953(transcript)	refseq:NP_014015.1|sgd:S000004901|dip:DIP-2628N|mint:P49955|ensemblfungi:YMR288W(gene)|ensemblfungi:YMR288W_mRNA(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005686"(U2 snRNP)|go:"GO:0071004"(U2-type prespliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR038737|rcsb pdb:5GM6|rcsb pdb:5LQW|rcsb pdb:5NRL|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:6G90	-	isoform-comment:"Contains a glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) at position 14."	crc64:27D26E4252A788E2	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:PSbIU++DIL6ysF0ccd3ZHzeJ5rs9606	rogid:t0fwQOOum/AO/xL8vhZdF2EGymo559292	intact-crc:BB3D3563AE52629D|rigid:WDsds/ohoeSWpFKVxrSEtMUSDIU	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P39682	uniprotkb:Q9UHX1-2	intact:EBI-612|uniprotkb:D6VZC9|uniprotkb:E9P8Z1|ensemblfungi:YML046W	intact:EBI-11529177|ensembl:ENSP00000322036|ensembl:ENSP00000478495	psi-mi:prp39_yeast(display_long)|uniprotkb:YM9827.06(orf name)|uniprotkb:YML046W(locus name)|uniprotkb:PRP39(gene name)|psi-mi:PRP39(display_short)	psi-mi:q9uhx1-2(display_long)|uniprotkb:PUF60(gene name)|psi-mi:PUF60(display_short)|uniprotkb:"60 kDa poly(U)-binding-splicing factor"(gene name synonym)|uniprotkb:FIR(gene name synonym)|uniprotkb:FUSE-binding protein-interacting repressor(gene name synonym)|uniprotkb:ROBPI(gene name synonym)|uniprotkb:Ro-binding protein 1(gene name synonym)|uniprotkb:SIAHBP1(gene name synonym)|uniprotkb:Siah-binding protein 1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554764|imex:IM-24995-4262	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013667.1|sgd:S000004509|dip:DIP-812N|mint:P39682|ensemblfungi:YML046W(gene)|ensemblfungi:YML046W_mRNA(transcript)|go:"GO:0000243"(commitment complex)|go:"GO:0000395"(mRNA 5'-splice site recognition)|go:"GO:0005685"(U1 snRNP)|go:"GO:0071004"(U2-type prespliceosome)|interpro:IPR003107(RNA-processing protein, HAT helix)|interpro:IPR011990(Tetratricopeptide-like helical)|rcsb pdb:5ZWN|rcsb pdb:6G90|rcsb pdb:6N7P|rcsb pdb:6N7R|rcsb pdb:6N7X	intact:EBI-1053259(isoform-parent)|ensembl:ENSG00000179950(gene)|ensembl:ENSG00000274081(gene)|ensembl:ENST00000349157(transcript)|ensembl:ENST00000612237(transcript)|uniprotkb:Q9UHX1-2(isoform-parent)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:urVLzQFKnYT1bYOs3yRd9dd7lMk559292	rogid:snVN9Lw5+MP2/aiq4z08ANwvr209606	intact-crc:CCDCAB0796CCADF3|rigid:C3+tQHyQVRHPL3u5/4qmzT1w/iw	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9UI14	uniprotkb:P38295	intact:EBI-712367|ensembl:ENSP00000222008|uniprotkb:Q7Z4Y2|uniprotkb:Q9Y3R1	intact:EBI-20890|uniprotkb:D6VQH2|ensemblfungi:YBR177C	psi-mi:praf1_human(display_long)|uniprotkb:PRA1 family protein 1(gene name synonym)|uniprotkb:RABAC1(gene name)|psi-mi:RABAC1(display_short)|uniprotkb:PRA1(gene name synonym)|uniprotkb:PRAF1(gene name synonym)	psi-mi:mcfs2_yeast(display_long)|uniprotkb:YBR177C(locus name)|uniprotkb:YBR1239(orf name)|uniprotkb:EHT1(gene name)|psi-mi:EHT1(display_short)|uniprotkb:Alcohol O-acetyltransferase(gene name synonym)|uniprotkb:Ethanol hexanoyl transferase 1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554804|imex:IM-24995-4272	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006414.2|ensembl:ENSG00000105404(gene)|ensembl:ENST00000222008(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0070064"(proline-rich region binding)|interpro:IPR004895(Prenylated rab acceptor PRA1)|mint:Q9UI14	refseq:NP_009736.3|sgd:S000000381|interpro:IPR012020(AB-hydrolase YheT, putative)|interpro:IPR000073(Alpha/beta hydrolase fold-1)|interpro:IPR000952(Protein of unknown function UPF0017, hydrolase-like, conserved site)|mint:P38295|interpro:IPR029058|ensemblfungi:YBR177C(gene)|ensemblfungi:YBR177C_mRNA(transcript)|go:"GO:0004026"(alcohol O-acetyltransferase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0008126"(acetylesterase activity)|go:"GO:0017171"(serine hydrolase activity)|go:"GO:0034319"(alcohol O-butanoyltransferase activity)|go:"GO:0034338"(short-chain carboxylesterase activity)|go:"GO:0044255"(cellular lipid metabolic process)|go:"GO:0047372"(acylglycerol lipase activity)|go:"GO:0051792"(medium-chain fatty acid biosynthetic process)|go:"GO:0051793"(medium-chain fatty acid catabolic process)|reactome:R-SCE-1483191	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:WS2rUY7yXRbR7pqWgfUCbnEiDbg9606	rogid:9arzlcrZmkK0VXN7Zw87dAe1Txc559292	intact-crc:B24B35F1F5C31561|rigid:PLLUrVsNaFuk2Qvs8fALPfUfHE4	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9UI14	uniprotkb:P40454	intact:EBI-712367|ensembl:ENSP00000222008|uniprotkb:Q7Z4Y2|uniprotkb:Q9Y3R1	intact:EBI-25278|uniprotkb:D6VVD4|ensemblfungi:YIL153W	psi-mi:praf1_human(display_long)|uniprotkb:PRA1 family protein 1(gene name synonym)|uniprotkb:RABAC1(gene name)|psi-mi:RABAC1(display_short)|uniprotkb:PRA1(gene name synonym)|uniprotkb:PRAF1(gene name synonym)	psi-mi:ptpa1_yeast(display_long)|uniprotkb:YIL153W(locus name)|uniprotkb:RRD1(gene name)|psi-mi:RRD1(display_short)|uniprotkb:NCS1(gene name synonym)|uniprotkb:YPA1(gene name synonym)|uniprotkb:Peptidyl-prolyl cis-trans isomerase PTPA-1(gene name synonym)|uniprotkb:Phosphotyrosyl phosphatase activator 1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554800|imex:IM-24995-4271	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006414.2|ensembl:ENSG00000105404(gene)|ensembl:ENST00000222008(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0070064"(proline-rich region binding)|interpro:IPR004895(Prenylated rab acceptor PRA1)|mint:Q9UI14	refseq:NP_012113.1|sgd:S000001415|mint:P40454|dip:DIP-5663N|ensemblfungi:YIL153W(gene)|ensemblfungi:YIL153W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006914"(autophagy)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008160"(protein tyrosine phosphatase activator activity)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0043618"(regulation of transcription from RNA polymerase II promoter in response to stress)|interpro:IPR004327(Phosphotyrosyl phosphatase activator, PTPA)|interpro:IPR037218|interpro:IPR043170|rcsb pdb:2IXO|rcsb pdb:2IXP	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:WS2rUY7yXRbR7pqWgfUCbnEiDbg9606	rogid:It2q8WlpmvLEZ1fqpRF5Fypw9Q4559292	intact-crc:2682A4AB710C47D4|rigid:AUXe+NvVLCGB7t8ALTMh9ZY60R4	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P49955	uniprotkb:Q9UHX1-6	intact:EBI-664|uniprotkb:D6W0B5|ensemblfungi:YMR288W	intact:EBI-11085298|ensembl:ENSP00000431960	psi-mi:sf3b1_yeast(display_long)|uniprotkb:YMR288W(locus name)|uniprotkb:YM8021.14(orf name)|uniprotkb:HSH155(gene name)|psi-mi:HSH155(display_short)	psi-mi:q9uhx1-6(display_long)|uniprotkb:PUF60(gene name)|psi-mi:PUF60(display_short)|uniprotkb:"60 kDa poly(U)-binding-splicing factor"(gene name synonym)|uniprotkb:FIR(gene name synonym)|uniprotkb:FUSE-binding protein-interacting repressor(gene name synonym)|uniprotkb:ROBPI(gene name synonym)|uniprotkb:Ro-binding protein 1(gene name synonym)|uniprotkb:SIAHBP1(gene name synonym)|uniprotkb:Siah-binding protein 1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554784|imex:IM-24995-4267	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014015.1|sgd:S000004901|dip:DIP-2628N|mint:P49955|ensemblfungi:YMR288W(gene)|ensemblfungi:YMR288W_mRNA(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005686"(U2 snRNP)|go:"GO:0071004"(U2-type prespliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR038737|rcsb pdb:5GM6|rcsb pdb:5LQW|rcsb pdb:5NRL|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:6G90	ensembl:ENSG00000179950(gene)|ensembl:ENST00000527197(transcript)|intact:EBI-1053259(isoform-parent)|uniprotkb:Q9UHX1-6(isoform-parent)	-	crc64:27D26E4252A788E2	isoform-comment:"Contains a glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) at position 14."	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:t0fwQOOum/AO/xL8vhZdF2EGymo559292	rogid:rSsTImwmpEAWMCxLzF5Y4zVdeFM9606	intact-crc:DE4D37CF20F78B86|rigid:8EH56eX/wnavTFpdm70DHzxrVZI	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9UHX1-6	uniprotkb:P39682	intact:EBI-11085298|ensembl:ENSP00000431960	intact:EBI-612|uniprotkb:D6VZC9|uniprotkb:E9P8Z1|ensemblfungi:YML046W	psi-mi:q9uhx1-6(display_long)|uniprotkb:PUF60(gene name)|psi-mi:PUF60(display_short)|uniprotkb:"60 kDa poly(U)-binding-splicing factor"(gene name synonym)|uniprotkb:FIR(gene name synonym)|uniprotkb:FUSE-binding protein-interacting repressor(gene name synonym)|uniprotkb:ROBPI(gene name synonym)|uniprotkb:Ro-binding protein 1(gene name synonym)|uniprotkb:SIAHBP1(gene name synonym)|uniprotkb:Siah-binding protein 1(gene name synonym)	psi-mi:prp39_yeast(display_long)|uniprotkb:YM9827.06(orf name)|uniprotkb:YML046W(locus name)|uniprotkb:PRP39(gene name)|psi-mi:PRP39(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554792|imex:IM-24995-4269	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000179950(gene)|ensembl:ENST00000527197(transcript)|intact:EBI-1053259(isoform-parent)|uniprotkb:Q9UHX1-6(isoform-parent)	refseq:NP_013667.1|sgd:S000004509|dip:DIP-812N|mint:P39682|ensemblfungi:YML046W(gene)|ensemblfungi:YML046W_mRNA(transcript)|go:"GO:0000243"(commitment complex)|go:"GO:0000395"(mRNA 5'-splice site recognition)|go:"GO:0005685"(U1 snRNP)|go:"GO:0071004"(U2-type prespliceosome)|interpro:IPR003107(RNA-processing protein, HAT helix)|interpro:IPR011990(Tetratricopeptide-like helical)|rcsb pdb:5ZWN|rcsb pdb:6G90|rcsb pdb:6N7P|rcsb pdb:6N7R|rcsb pdb:6N7X	-	isoform-comment:"Contains a glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) at position 14."	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:rSsTImwmpEAWMCxLzF5Y4zVdeFM9606	rogid:urVLzQFKnYT1bYOs3yRd9dd7lMk559292	intact-crc:6413510FEFAE896E|rigid:h06io8tHQ7CJ44GBbEpCK/JxMjc	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P38340	uniprotkb:Q9UHX1-6	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-11085298|ensembl:ENSP00000431960	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:q9uhx1-6(display_long)|uniprotkb:PUF60(gene name)|psi-mi:PUF60(display_short)|uniprotkb:"60 kDa poly(U)-binding-splicing factor"(gene name synonym)|uniprotkb:FIR(gene name synonym)|uniprotkb:FUSE-binding protein-interacting repressor(gene name synonym)|uniprotkb:ROBPI(gene name synonym)|uniprotkb:Ro-binding protein 1(gene name synonym)|uniprotkb:SIAHBP1(gene name synonym)|uniprotkb:Siah-binding protein 1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554788|imex:IM-24995-4268	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F	ensembl:ENSG00000179950(gene)|ensembl:ENST00000527197(transcript)|intact:EBI-1053259(isoform-parent)|uniprotkb:Q9UHX1-6(isoform-parent)	-	crc64:66699F37B0013088	isoform-comment:"Contains a glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) at position 14."	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:rSsTImwmpEAWMCxLzF5Y4zVdeFM9606	intact-crc:93E66DE2B8BAEB36|rigid:AGw+HnxGbnqrYFDQxeuC0bO441g	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P32502	uniprotkb:Q9UHX1-6	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	intact:EBI-11085298|ensembl:ENSP00000431960	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:q9uhx1-6(display_long)|uniprotkb:PUF60(gene name)|psi-mi:PUF60(display_short)|uniprotkb:"60 kDa poly(U)-binding-splicing factor"(gene name synonym)|uniprotkb:FIR(gene name synonym)|uniprotkb:FUSE-binding protein-interacting repressor(gene name synonym)|uniprotkb:ROBPI(gene name synonym)|uniprotkb:Ro-binding protein 1(gene name synonym)|uniprotkb:SIAHBP1(gene name synonym)|uniprotkb:Siah-binding protein 1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554796|imex:IM-24995-4270	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731	ensembl:ENSG00000179950(gene)|ensembl:ENST00000527197(transcript)|intact:EBI-1053259(isoform-parent)|uniprotkb:Q9UHX1-6(isoform-parent)	-	crc64:A5409FAF1594854C	isoform-comment:"Contains a glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) at position 14."	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	rogid:rSsTImwmpEAWMCxLzF5Y4zVdeFM9606	intact-crc:A6BE4B3422E83FD3|rigid:t73OVeVNVLQvgjkmczlo9d3vUIw	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9UI14	uniprotkb:P53296	intact:EBI-712367|ensembl:ENSP00000222008|uniprotkb:Q7Z4Y2|uniprotkb:Q9Y3R1	intact:EBI-3165|uniprotkb:E9P955|ensemblfungi:YGR177C|uniprotkb:D6VUW1	psi-mi:praf1_human(display_long)|uniprotkb:PRA1 family protein 1(gene name synonym)|uniprotkb:RABAC1(gene name)|psi-mi:RABAC1(display_short)|uniprotkb:PRA1(gene name synonym)|uniprotkb:PRAF1(gene name synonym)	psi-mi:atf2_yeast(display_long)|uniprotkb:ATF2(gene name)|psi-mi:ATF2(display_short)|uniprotkb:"Acetyl-CoA:pregnenolone acetyltransferase"(gene name synonym)|uniprotkb:G7135(orf name)|uniprotkb:YGR177C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554832|imex:IM-24995-4279	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006414.2|ensembl:ENSG00000105404(gene)|ensembl:ENST00000222008(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0070064"(proline-rich region binding)|interpro:IPR004895(Prenylated rab acceptor PRA1)|mint:Q9UI14	refseq:NP_011693.1|sgd:S000003409|ensemblfungi:YGR177C(gene)|ensemblfungi:YGR177C_mRNA(transcript)|go:"GO:0004026"(alcohol O-acetyltransferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0008080"(N-acetyltransferase activity)|go:"GO:0008202"(steroid metabolic process)|go:"GO:0009636"(response to toxic substance)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0034209"(sterol acetylation)|go:"GO:1901089"(acetate ester metabolic process involved in fermentation)|interpro:IPR010828(Alcohol acetyltransferase)|dip:DIP-5544N|mint:P53296	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:WS2rUY7yXRbR7pqWgfUCbnEiDbg9606	rogid:tFI+2rcFXzDfDteDJv8wwBGUh0c559292	intact-crc:6A640A587473417A|rigid:mh1TetBF8MwxyPIhB9F7I1csQsE	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9UI14	uniprotkb:P38340	intact:EBI-712367|ensembl:ENSP00000222008|uniprotkb:Q7Z4Y2|uniprotkb:Q9Y3R1	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:praf1_human(display_long)|uniprotkb:PRA1 family protein 1(gene name synonym)|uniprotkb:RABAC1(gene name)|psi-mi:RABAC1(display_short)|uniprotkb:PRA1(gene name synonym)|uniprotkb:PRAF1(gene name synonym)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554828|imex:IM-24995-4278	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006414.2|ensembl:ENSG00000105404(gene)|ensembl:ENST00000222008(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0070064"(proline-rich region binding)|interpro:IPR004895(Prenylated rab acceptor PRA1)|mint:Q9UI14	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F	-	-	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:WS2rUY7yXRbR7pqWgfUCbnEiDbg9606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:741AB6F971B23C38|rigid:BK1n3/d6sldlD+wVYtMoikRhz2E	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9UI14	uniprotkb:P39518	intact:EBI-712367|ensembl:ENSP00000222008|uniprotkb:Q7Z4Y2|uniprotkb:Q9Y3R1	intact:EBI-10082|uniprotkb:D3DLR3|ensemblfungi:YER015W	psi-mi:praf1_human(display_long)|uniprotkb:PRA1 family protein 1(gene name synonym)|uniprotkb:RABAC1(gene name)|psi-mi:RABAC1(display_short)|uniprotkb:PRA1(gene name synonym)|uniprotkb:PRAF1(gene name synonym)	psi-mi:lcf2_yeast(display_long)|uniprotkb:YER015W(locus name)|uniprotkb:FAA2(gene name)|psi-mi:FAA2(display_short)|uniprotkb:FAM1(gene name synonym)|uniprotkb:Long-chain acyl-CoA synthetase 2(gene name synonym)|uniprotkb:Fatty acid activator 2(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554824|imex:IM-24995-4277	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006414.2|ensembl:ENSG00000105404(gene)|ensembl:ENST00000222008(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0070064"(proline-rich region binding)|interpro:IPR004895(Prenylated rab acceptor PRA1)|mint:Q9UI14	sgd:S000000817|ensemblfungi:YER015W_mRNA(transcript)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0004467"(long-chain fatty acid-CoA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0015910"(long-chain fatty acid import into peroxisome)|go:"GO:0015916"(fatty-acyl-CoA transport)|go:"GO:0016020"(membrane)|go:"GO:0031956"(medium-chain fatty acid-CoA ligase activity)|go:"GO:0031957"(very long-chain fatty acid-CoA ligase activity)|go:"GO:0042760"(very long-chain fatty acid catabolic process)|go:"GO:0102391"(decanoate-CoA ligase activity)|ensemblfungi:YER015W(gene)|interpro:IPR020845|interpro:IPR000873(AMP-dependent synthetase and ligase)|reactome:R-SCE-75876|refseq:NP_010931.3|dip:DIP-6565N	-	-	crc64:1E023C18682805BC	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:WS2rUY7yXRbR7pqWgfUCbnEiDbg9606	rogid:N0W+wPvCsl01y0k8hJZ156LztOo559292	intact-crc:0B4A4137192B268E|rigid:jPhhAt1Bsy7WNtT3Ax4kIVJhUQo	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P32502	uniprotkb:Q9UI14	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	intact:EBI-712367|ensembl:ENSP00000222008|uniprotkb:Q7Z4Y2|uniprotkb:Q9Y3R1	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:praf1_human(display_long)|uniprotkb:PRA1 family protein 1(gene name synonym)|uniprotkb:RABAC1(gene name)|psi-mi:RABAC1(display_short)|uniprotkb:PRA1(gene name synonym)|uniprotkb:PRAF1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554808|imex:IM-24995-4273	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731	refseq:NP_006414.2|ensembl:ENSG00000105404(gene)|ensembl:ENST00000222008(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0070064"(proline-rich region binding)|interpro:IPR004895(Prenylated rab acceptor PRA1)|mint:Q9UI14	-	crc64:A5409FAF1594854C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	rogid:WS2rUY7yXRbR7pqWgfUCbnEiDbg9606	intact-crc:D1EB36D3E54793DB|rigid:1nv/6BMInnXsSwk8QbyMG8XZv/s	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9UI14	uniprotkb:Q01590	intact:EBI-712367|ensembl:ENSP00000222008|uniprotkb:Q7Z4Y2|uniprotkb:Q9Y3R1	intact:EBI-16930|uniprotkb:D6VY28|ensemblfungi:YLR026C	psi-mi:praf1_human(display_long)|uniprotkb:PRA1 family protein 1(gene name synonym)|uniprotkb:RABAC1(gene name)|psi-mi:RABAC1(display_short)|uniprotkb:PRA1(gene name synonym)|uniprotkb:PRAF1(gene name synonym)	psi-mi:sed5_yeast(display_long)|uniprotkb:SED5(gene name)|psi-mi:SED5(display_short)|uniprotkb:YLR026C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554816|imex:IM-24995-4275	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006414.2|ensembl:ENSG00000105404(gene)|ensembl:ENST00000222008(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0070064"(proline-rich region binding)|interpro:IPR004895(Prenylated rab acceptor PRA1)|mint:Q9UI14	refseq:NP_013126.1|sgd:S000004016|ensemblfungi:YLR026C(gene)|ensemblfungi:YLR026C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0006906"(vesicle fusion)|go:"GO:0090083"(regulation of inclusion body assembly)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|interpro:IPR021538|rcsb pdb:1MQS|rcsb pdb:1PD0|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|reactome:R-SCE-204005|reactome:R-SCE-5694530|reactome:R-SCE-6807878|reactome:R-SCE-6811438|reactome:R-SCE-9609523|go:"GO:0031201"(SNARE complex)|go:"GO:0048278"(vesicle docking)|go:"GO:0048280"(vesicle fusion with Golgi apparatus)|dip:DIP-2489N|mint:Q01590	-	-	crc64:B3192B57269A0B83	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:WS2rUY7yXRbR7pqWgfUCbnEiDbg9606	rogid:c+W+86qfjxcvWWJ9nMScyH5TjNA559292	intact-crc:77F3D96B086920D5|rigid:RgVmkjyaRYAZv3poNv9+Q5mqOo4	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9UI14	uniprotkb:Q05637	intact:EBI-712367|ensembl:ENSP00000222008|uniprotkb:Q7Z4Y2|uniprotkb:Q9Y3R1	intact:EBI-37326|uniprotkb:D6VSR1|ensemblfungi:YDR281C	psi-mi:praf1_human(display_long)|uniprotkb:PRA1 family protein 1(gene name synonym)|uniprotkb:RABAC1(gene name)|psi-mi:RABAC1(display_short)|uniprotkb:PRA1(gene name synonym)|uniprotkb:PRAF1(gene name synonym)	psi-mi:phm6_yeast(display_long)|uniprotkb:PHM6(gene name)|psi-mi:PHM6(display_short)|uniprotkb:D9954.14(orf name)|uniprotkb:YDR281C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554812|imex:IM-24995-4274	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006414.2|ensembl:ENSG00000105404(gene)|ensembl:ENST00000222008(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0070064"(proline-rich region binding)|interpro:IPR004895(Prenylated rab acceptor PRA1)|mint:Q9UI14	sgd:S000002689|refseq:NP_010567.1|dip:DIP-4775N|ensemblfungi:YDR281C(gene)|ensemblfungi:YDR281C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0016021"(integral component of membrane)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:WS2rUY7yXRbR7pqWgfUCbnEiDbg9606	rogid:4CXswPUeUtOazQ3jQAWOO1E96Lg559292	intact-crc:724056CA9F00DDCF|rigid:2WjLcCnzVfgd0x11TZ7gu507FkI	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9UI14	uniprotkb:P38815	intact:EBI-712367|ensembl:ENSP00000222008|uniprotkb:Q7Z4Y2|uniprotkb:Q9Y3R1	intact:EBI-24665|uniprotkb:D3DL55|ensemblfungi:YHR105W	psi-mi:praf1_human(display_long)|uniprotkb:PRA1 family protein 1(gene name synonym)|uniprotkb:RABAC1(gene name)|psi-mi:RABAC1(display_short)|uniprotkb:PRA1(gene name synonym)|uniprotkb:PRAF1(gene name synonym)	psi-mi:ypt35_yeast(display_long)|uniprotkb:YHR105W(locus name)|uniprotkb:YPT35(gene name)|psi-mi:YPT35(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554820|imex:IM-24995-4276	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006414.2|ensembl:ENSG00000105404(gene)|ensembl:ENST00000222008(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0070064"(proline-rich region binding)|interpro:IPR004895(Prenylated rab acceptor PRA1)|mint:Q9UI14	refseq:NP_011973.1|sgd:S000001147|dip:DIP-1881N|ensemblfungi:YHR105W(gene)|ensemblfungi:YHR105W_mRNA(transcript)|go:"GO:0005768"(endosome)|go:"GO:0010008"(endosome membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|interpro:IPR001683(Phox-like)|interpro:IPR036871|interpro:IPR037917	-	-	crc64:2ADD21AF107094DC	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:WS2rUY7yXRbR7pqWgfUCbnEiDbg9606	rogid:fUTJG8BaTveH3zB/0W1vNh4BU2Y559292	intact-crc:24343A0CAC20D7DA|rigid:prvpKhWrJiDUl4kjr1YUwrA7ZTc	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P23059	uniprotkb:Q9UJV3-2	intact:EBI-10950|ensemblfungi:YCR020C-A|uniprotkb:D6VR29	intact:EBI-10172526|ensembl:ENSP00000413976	psi-mi:naa38_yeast(display_long)|uniprotkb:MAK31(gene name)|psi-mi:MAK31(display_short)|uniprotkb:YCR020C-A(locus name)|uniprotkb:YCR20C-A(orf name)|uniprotkb:L-A virus GAG protein N-acetyltransferase subunit MAK31(gene name synonym)|uniprotkb:Maintenance of killer protein 31(gene name synonym)|uniprotkb:NAA38(gene name synonym)|uniprotkb:N-terminal acetyltransferase C complex subunit MAK31(gene name synonym)	psi-mi:q9ujv3-2(display_long)|uniprotkb:RING-type E3 ubiquitin transferase MID2(gene name synonym)|uniprotkb:FXY2(gene name synonym)|uniprotkb:Midin-2(gene name synonym)|uniprotkb:Midline defect 2(gene name synonym)|uniprotkb:Midline-2(gene name synonym)|uniprotkb:RING finger protein 60(gene name synonym)|uniprotkb:RNF60(gene name synonym)|uniprotkb:TRIM1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 1(gene name synonym)|uniprotkb:MID2(gene name)|psi-mi:MID2(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554864|imex:IM-24995-4287	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YCR020C-A(gene)|ensemblfungi:YCR020C-A_mRNA(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005688"(U6 snRNP)|go:"GO:0005829"(cytosol)|go:"GO:0006474"(N-terminal protein amino acid acetylation)|go:"GO:0016070"(RNA metabolic process)|go:"GO:0031417"(NatC complex)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071011"(precatalytic spliceosome)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR034110|rcsb pdb:6YGA|rcsb pdb:6YGB|rcsb pdb:6YGC|rcsb pdb:6YGD|refseq:NP_009948.1|sgd:S000000614|mint:P23059|dip:DIP-1429N	intact:EBI-751983(isoform-parent)|uniprotkb:Q9UJV3-2(isoform-parent)|ensembl:ENSG00000080561(gene)|ensembl:ENST00000443968(transcript)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:VUwG0xxj0NeyZKANRYCAgJGuqs8559292	rogid:/FJ+V2H7SaWon7caUWkEkmHFVxQ9606	intact-crc:C47C117CD46093FB|rigid:UHUc4T8tYrgIDj6hGi2K0oJGCYk	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q12259	uniprotkb:Q9UJV3-2	intact:EBI-30776|uniprotkb:D6VYA8|ensemblfungi:YLR108C	intact:EBI-10172526|ensembl:ENSP00000413976	psi-mi:yl108_yeast(display_long)|uniprotkb:L2913(orf name)|uniprotkb:YLR108C(locus name)	psi-mi:q9ujv3-2(display_long)|uniprotkb:RING-type E3 ubiquitin transferase MID2(gene name synonym)|uniprotkb:FXY2(gene name synonym)|uniprotkb:Midin-2(gene name synonym)|uniprotkb:Midline defect 2(gene name synonym)|uniprotkb:Midline-2(gene name synonym)|uniprotkb:RING finger protein 60(gene name synonym)|uniprotkb:RNF60(gene name synonym)|uniprotkb:TRIM1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 1(gene name synonym)|uniprotkb:MID2(gene name)|psi-mi:MID2(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554860|imex:IM-24995-4286	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013209.1|sgd:S000004098|dip:DIP-4075N|ensemblfungi:YLR108C(gene)|ensemblfungi:YLR108C_mRNA(transcript)|go:"GO:0005634"(nucleus)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)	intact:EBI-751983(isoform-parent)|uniprotkb:Q9UJV3-2(isoform-parent)|ensembl:ENSG00000080561(gene)|ensembl:ENST00000443968(transcript)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:CzknxXhhvgMp3J0/oi197EgZ05U559292	rogid:/FJ+V2H7SaWon7caUWkEkmHFVxQ9606	intact-crc:7B1BBF3620CECD52|rigid:a7+6SPKWP0N9Pw7PFvF9AgHEh4w	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q12056	uniprotkb:Q9UJC3	intact:EBI-30488|uniprotkb:D6W2T0|ensemblfungi:YOR226C	intact:EBI-746704|uniprotkb:O60561|uniprotkb:Q5TG44|uniprotkb:A8MU44|uniprotkb:B4DX15|uniprotkb:A8K8E9|intact:EBI-10969618|ensembl:ENSP00000360252	psi-mi:isu2_yeast(display_long)|uniprotkb:Iron sulfur cluster scaffold protein 2(gene name synonym)|uniprotkb:ISU2(gene name)|psi-mi:ISU2(display_short)|uniprotkb:NUA2(gene name synonym)|uniprotkb:YOR226C(locus name)	psi-mi:hook1_human(display_long)|uniprotkb:HOOK1(gene name)|psi-mi:HOOK1(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554856|imex:IM-24995-4285	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005752|refseq:NP_014869.3|dip:DIP-4123N|ensemblfungi:YOR226C(gene)|ensemblfungi:YOR226C_mRNA(transcript)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005737"(cytoplasm)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR002871(NIF system FeS cluster assembly, NifU, N-terminal)|interpro:IPR011339(ISC system FeS cluster assembly, IscU scaffold)	refseq:NP_056972.1|ensembl:ENSG00000134709(gene)|ensembl:ENST00000371208(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0007030"(Golgi organization)|go:"GO:0007032"(endosome organization)|go:"GO:0007040"(lysosome organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0015031"(protein transport)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0051959"(dynein light intermediate chain binding)|go:"GO:0070695"(FHF complex)|go:"GO:1905198"(manchette assembly)|go:"GO:1905719"(protein localization to perinuclear region of cytoplasm)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR008636(HOOK)|interpro:IPR036872|interpro:IPR043936|mint:Q9UJC3	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:e4qx7ic8wpO6cTHGl73je/JVzMY559292	rogid:QOcYbuKfnNIlNKzos5v+0+A2h3I9606	intact-crc:B09F923EDF316104|rigid:gr7ksJ1UTUAWMb+nNZCp/sOdtA0	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9UJ70-2	uniprotkb:P43556	intact:EBI-11526455|ensembl:ENSP00000389087|ensembl:ENSP00000477639	intact:EBI-22845|uniprotkb:D6VTI3|ensemblfungi:YFL047W	psi-mi:q9uj70-2(display_long)|uniprotkb:GlcNAc kinase(gene name synonym)|uniprotkb:NAGK(gene name)|psi-mi:NAGK(display_short)	psi-mi:rgd2_yeast(display_long)|uniprotkb:RGD2(gene name)|psi-mi:RGD2(display_short)|uniprotkb:YFL047W(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554836|imex:IM-24995-4280	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-372578(isoform-parent)|ensembl:ENSG00000124357(gene)|ensembl:ENST00000455662(transcript)|ensembl:ENST00000613852(transcript)|uniprotkb:Q9UJ70-2(isoform-parent)	refseq:NP_428268.1|sgd:S000001847|dip:DIP-4958N|mint:P43556|go:"GO:0005935"(cellular bud neck)|interpro:IPR031160|reactome:R-SCE-8856828|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0032153"(cell division site)|interpro:IPR000198(RhoGAP)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR027267|ensemblfungi:YFL047W(gene)|ensemblfungi:YFL047W_mRNA(transcript)|go:"GO:0000935"(division septum)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005934"(cellular bud tip)	-	-	crc64:52CF174C5F650157	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:zoy4C+HK341UnmDRUlMuJucczr89606	rogid:TaphLAmYObi9RXMbE2tJDrHtVxA559292	intact-crc:EFD2CDF90D9B4CA1|rigid:7yBeKNZ0uHkUv4s/ch83jqe0tK4	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9UJC3	uniprotkb:P20133	intact:EBI-746704|uniprotkb:O60561|uniprotkb:Q5TG44|uniprotkb:A8MU44|uniprotkb:B4DX15|uniprotkb:A8K8E9|intact:EBI-10969618|ensembl:ENSP00000360252	intact:EBI-3559|uniprotkb:P32433|uniprotkb:D6W4H7|ensemblfungi:YPR176C	psi-mi:hook1_human(display_long)|uniprotkb:HOOK1(gene name)|psi-mi:HOOK1(display_short)	psi-mi:pgtb2_yeast(display_long)|uniprotkb:Geranylgeranyl transferase type II subunit beta(gene name synonym)|uniprotkb:Type II protein geranyl-geranyltransferase subunit beta(gene name synonym)|uniprotkb:YPT1/SEC4 proteins geranylgeranyltransferase subunit beta(gene name synonym)|uniprotkb:BET2(gene name)|psi-mi:BET2(display_short)|uniprotkb:YPR176C(locus name)|uniprotkb:P9705.12(orf name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554848|imex:IM-24995-4283	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_056972.1|ensembl:ENSG00000134709(gene)|ensembl:ENST00000371208(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0007030"(Golgi organization)|go:"GO:0007032"(endosome organization)|go:"GO:0007040"(lysosome organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0015031"(protein transport)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0051959"(dynein light intermediate chain binding)|go:"GO:0070695"(FHF complex)|go:"GO:1905198"(manchette assembly)|go:"GO:1905719"(protein localization to perinuclear region of cytoplasm)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR008636(HOOK)|interpro:IPR036872|interpro:IPR043936|mint:Q9UJC3	refseq:NP_015502.1|sgd:S000006380|reactome:R-SCE-6803205|reactome:R-SCE-8873719|dip:DIP-2214N|ensemblfungi:YPR176C(gene)|ensemblfungi:YPR176C_mRNA(transcript)|go:"GO:0004663"(Rab geranylgeranyltransferase activity)|go:"GO:0005829"(cytosol)|go:"GO:0005968"(Rab-protein geranylgeranyltransferase complex)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0008270"(zinc ion binding)|go:"GO:0018342"(protein prenylation)|go:"GO:0018344"(protein geranylgeranylation)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001330(Prenyltransferase/squalene oxidase)|interpro:IPR008930(Terpenoid cylases/protein prenyltransferase alpha-alpha toroid)|interpro:IPR026873	-	-	crc64:6A9C44DFBE62AAFC	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:QOcYbuKfnNIlNKzos5v+0+A2h3I9606	rogid:Fxribu0N2yK6IA2GZDfO0YmqLAo559292	intact-crc:C77C078C54ECFC47|rigid:FQ1SnE45bUOCAXYw9TLiJyl8nCw	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P25299	uniprotkb:Q9UJ83	intact:EBI-15640|uniprotkb:D6VU95|ensemblfungi:YGL044C	intact:EBI-746580|uniprotkb:Q9BV42|uniprotkb:Q9P0A2|ensembl:ENSP00000323811|uniprotkb:E9PEN4|uniprotkb:B4DWI1|uniprotkb:B4DXI5	psi-mi:rna15_yeast(display_long)|uniprotkb:YGL044C(locus name)|uniprotkb:RNA15(gene name)|psi-mi:RNA15(display_short)	psi-mi:hacl1_human(display_long)|uniprotkb:2-hydroxyphytanoyl-CoA lyase(gene name synonym)|uniprotkb:Phytanoyl-CoA 2-hydroxylase 2(gene name synonym)|uniprotkb:HACL1(gene name)|psi-mi:HACL1(display_short)|uniprotkb:HPCL2(gene name synonym)|uniprotkb:HSPC279(orf name)|uniprotkb:HPCL(gene name synonym)|uniprotkb:PHYH2(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554844|imex:IM-24995-4282	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011471.1|sgd:S000003012|ensemblfungi:YGL044C(gene)|ensemblfungi:YGL044C_mRNA(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0005849"(mRNA cleavage factor complex)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0072423"(response to DNA damage checkpoint signaling)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR026896|interpro:IPR035979|interpro:IPR038192|rcsb pdb:2KM8|rcsb pdb:2L9B|rcsb pdb:2X1A|rcsb pdb:2X1B|rcsb pdb:2X1F|dip:DIP-1489N|mint:P25299	refseq:NP_001271344.1|refseq:NP_036392.2|ensembl:ENSG00000131373(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005777"(peroxisome)|ensembl:ENST00000321169(transcript)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006625"(protein targeting to peroxisome)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0016830"(carbon-carbon lyase activity)|go:"GO:0030976"(thiamine pyrophosphate binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0097089"(methyl-branched fatty acid metabolic process)|go:"GO:0106360"(2-hydroxy-3-methylhexadecanoyl-CoA lyase activity)|go:"GO:0106376"(2-hydroxyphytanoyl-CoA lyase activity)|go:"GO:1903512"(phytanic acid metabolic process)|interpro:IPR011766(Thiamine pyrophosphate enzyme, C-terminal TPP-binding)|interpro:IPR012000(Thiamine pyrophosphate enzyme, central region)|interpro:IPR012001(Thiamine pyrophosphate enzyme, N-terminal TPP binding region)|interpro:IPR029035|interpro:IPR029061|reactome:R-HSA-389599|reactome:R-HSA-9033241|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001561"(fatty acid alpha-oxidation)|refseq:NP_001271342.1|refseq:NP_001271345.1	-	crc64:10053B8648A71ECB	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:TqfxsTHAh9CPJJ6Q7uH6kz988hk559292	rogid:030QpE5/e+3ZEuyUaK+RM3w8x4A9606	intact-crc:832FA55E36BCB45A|rigid:Ufyq0B2HZmr8lq+Ii+gGlqTRJ1E	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P32502	uniprotkb:Q9UJ70-2	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	intact:EBI-11526455|ensembl:ENSP00000389087|ensembl:ENSP00000477639	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:q9uj70-2(display_long)|uniprotkb:GlcNAc kinase(gene name synonym)|uniprotkb:NAGK(gene name)|psi-mi:NAGK(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554840|imex:IM-24995-4281	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731	intact:EBI-372578(isoform-parent)|ensembl:ENSG00000124357(gene)|ensembl:ENST00000455662(transcript)|ensembl:ENST00000613852(transcript)|uniprotkb:Q9UJ70-2(isoform-parent)	-	crc64:A5409FAF1594854C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	rogid:zoy4C+HK341UnmDRUlMuJucczr89606	intact-crc:72FD170EDDD746B0|rigid:n0pwos02ttUq0m9zwT4vZ4lEN7E	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P32502	uniprotkb:Q9UJC3	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	intact:EBI-746704|uniprotkb:O60561|uniprotkb:Q5TG44|uniprotkb:A8MU44|uniprotkb:B4DX15|uniprotkb:A8K8E9|intact:EBI-10969618|ensembl:ENSP00000360252	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:hook1_human(display_long)|uniprotkb:HOOK1(gene name)|psi-mi:HOOK1(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554852|imex:IM-24995-4284	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731	refseq:NP_056972.1|ensembl:ENSG00000134709(gene)|ensembl:ENST00000371208(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0007030"(Golgi organization)|go:"GO:0007032"(endosome organization)|go:"GO:0007040"(lysosome organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0015031"(protein transport)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0051959"(dynein light intermediate chain binding)|go:"GO:0070695"(FHF complex)|go:"GO:1905198"(manchette assembly)|go:"GO:1905719"(protein localization to perinuclear region of cytoplasm)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR008636(HOOK)|interpro:IPR036872|interpro:IPR043936|mint:Q9UJC3	-	crc64:A5409FAF1594854C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	rogid:QOcYbuKfnNIlNKzos5v+0+A2h3I9606	intact-crc:78712CC3458C2580|rigid:7kYUYjTM18DA+gT+GyTew1DPD6Y	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9UJV3-2	uniprotkb:Q06630	intact:EBI-10172526|ensembl:ENSP00000413976	intact:EBI-36794|uniprotkb:D6VSS5|ensemblfungi:YDR296W	psi-mi:q9ujv3-2(display_long)|uniprotkb:RING-type E3 ubiquitin transferase MID2(gene name synonym)|uniprotkb:FXY2(gene name synonym)|uniprotkb:Midin-2(gene name synonym)|uniprotkb:Midline defect 2(gene name synonym)|uniprotkb:Midline-2(gene name synonym)|uniprotkb:RING finger protein 60(gene name synonym)|uniprotkb:RNF60(gene name synonym)|uniprotkb:TRIM1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 1(gene name synonym)|uniprotkb:MID2(gene name)|psi-mi:MID2(display_short)	psi-mi:mhr1_yeast(display_long)|uniprotkb:MHR1(gene name)|psi-mi:MHR1(display_short)|uniprotkb:YDR296W(locus name)|uniprotkb:Cross-linked transcription component 1(gene name synonym)|uniprotkb:XTC1(gene name synonym)|uniprotkb:Mitochondrial large ribosomal subunit protein mL67(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554888|imex:IM-24995-4293	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-751983(isoform-parent)|uniprotkb:Q9UJV3-2(isoform-parent)|ensembl:ENSG00000080561(gene)|ensembl:ENST00000443968(transcript)	sgd:S000002704|refseq:NP_010582.3|mint:Q06630|dip:DIP-5727N|ensemblfungi:YDR296W(gene)|ensemblfungi:YDR296W_mRNA(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0000150"(DNA strand exchange activity)|go:"GO:0003677"(DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0006310"(DNA recombination)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0032543"(mitochondrial translation)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0090297"(positive regulation of mitochondrial DNA replication)|interpro:IPR024629|rcsb pdb:3J6B|rcsb pdb:5MRC|rcsb pdb:5MRE|rcsb pdb:5MRF	-	-	crc64:F26903A4814091C4	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:/FJ+V2H7SaWon7caUWkEkmHFVxQ9606	rogid:eA38S7UNOpP716XSQ0zzhYm2TqA559292	intact-crc:8DC0098809DA160D|rigid:uav9RSJq+r8k5yH7EhWpKx59nQ0	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9UJV3-2	uniprotkb:P46945	intact:EBI-10172526|ensembl:ENSP00000413976	intact:EBI-11531997|uniprotkb:D6VTX6|ensemblfungi:YGL176C	psi-mi:q9ujv3-2(display_long)|uniprotkb:RING-type E3 ubiquitin transferase MID2(gene name synonym)|uniprotkb:FXY2(gene name synonym)|uniprotkb:Midin-2(gene name synonym)|uniprotkb:Midline defect 2(gene name synonym)|uniprotkb:Midline-2(gene name synonym)|uniprotkb:RING finger protein 60(gene name synonym)|uniprotkb:RNF60(gene name synonym)|uniprotkb:TRIM1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 1(gene name synonym)|uniprotkb:MID2(gene name)|psi-mi:MID2(display_short)	psi-mi:ygs6_yeast(display_long)|uniprotkb:G1636(orf name)|uniprotkb:YGL176C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554884|imex:IM-24995-4292	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-751983(isoform-parent)|uniprotkb:Q9UJV3-2(isoform-parent)|ensembl:ENSG00000080561(gene)|ensembl:ENST00000443968(transcript)	refseq:NP_011339.1|sgd:S000003144|ensemblfungi:YGL176C(gene)|ensemblfungi:YGL176C_mRNA(transcript)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/03/16	rogid:/FJ+V2H7SaWon7caUWkEkmHFVxQ9606	rogid:vWpHYgTdiHjJQSg5gUHb94U3Uhk559292	intact-crc:731A565999C6BC0B|rigid:eG8fkGozVkfJ5tFaS2KYEDcONnA	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P39946	uniprotkb:Q9UJV3-2	intact:EBI-12838|uniprotkb:D6W2W9|ensemblfungi:YOR269W	intact:EBI-10172526|ensembl:ENSP00000413976	psi-mi:lis1_yeast(display_long)|uniprotkb:PAC1(gene name)|psi-mi:PAC1(display_short)|uniprotkb:nudF homolog(gene name synonym)|uniprotkb:LIS1(gene name synonym)|uniprotkb:Lissencephaly-1 homolog(gene name synonym)|uniprotkb:YOR269W(locus name)	psi-mi:q9ujv3-2(display_long)|uniprotkb:RING-type E3 ubiquitin transferase MID2(gene name synonym)|uniprotkb:FXY2(gene name synonym)|uniprotkb:Midin-2(gene name synonym)|uniprotkb:Midline defect 2(gene name synonym)|uniprotkb:Midline-2(gene name synonym)|uniprotkb:RING finger protein 60(gene name synonym)|uniprotkb:RNF60(gene name synonym)|uniprotkb:TRIM1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 1(gene name synonym)|uniprotkb:MID2(gene name)|psi-mi:MID2(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554868|imex:IM-24995-4288	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YOR269W(gene)|ensemblfungi:YOR269W_mRNA(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007097"(nuclear migration)|go:"GO:0030473"(nuclear migration along microtubule)|go:"GO:0031023"(microtubule organizing center organization)|go:"GO:0042802"(identical protein binding)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0051012"(microtubule sliding)|go:"GO:0051301"(cell division)|go:"GO:0070840"(dynein complex binding)|go:"GO:1903033"(positive regulation of microtubule plus-end binding)|go:"GO:2000574"(obsolete regulation of microtubule motor activity)|go:"GO:2000582"(obsolete positive regulation of microtubule motor activity, plus-end-directed)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR017252(Dynein regulator)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|interpro:IPR037190|rcsb pdb:5VH9|rcsb pdb:5VLJ|refseq:NP_014912.1|sgd:S000005795|mint:P39946|dip:DIP-1485N	intact:EBI-751983(isoform-parent)|uniprotkb:Q9UJV3-2(isoform-parent)|ensembl:ENSG00000080561(gene)|ensembl:ENST00000443968(transcript)	-	crc64:E667E4BA7602FB3B	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:tyU5fR5V8csklk2QqAQHt3Mmz7c559292	rogid:/FJ+V2H7SaWon7caUWkEkmHFVxQ9606	intact-crc:E6E0641A839CF12F|rigid:ARbzysojGHvgGNGr1TPCQwd7Vfc	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P47041	uniprotkb:Q9UJV3-2	intact:EBI-25889|uniprotkb:D6VWC4|ensemblfungi:YJL058C	intact:EBI-10172526|ensembl:ENSP00000413976	psi-mi:bit61_yeast(display_long)|uniprotkb:YJL058C(locus name)|uniprotkb:J1141(orf name)|uniprotkb:61 kDa binding partner of TOR2 protein(gene name synonym)|uniprotkb:BIT61(gene name)|psi-mi:BIT61(display_short)	psi-mi:q9ujv3-2(display_long)|uniprotkb:RING-type E3 ubiquitin transferase MID2(gene name synonym)|uniprotkb:FXY2(gene name synonym)|uniprotkb:Midin-2(gene name synonym)|uniprotkb:Midline defect 2(gene name synonym)|uniprotkb:Midline-2(gene name synonym)|uniprotkb:RING finger protein 60(gene name synonym)|uniprotkb:RNF60(gene name synonym)|uniprotkb:TRIM1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 1(gene name synonym)|uniprotkb:MID2(gene name)|psi-mi:MID2(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554876|imex:IM-24995-4290	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012477.1|sgd:S000003594|dip:DIP-1444N|reactome:R-SCE-1257604|reactome:R-SCE-389357|reactome:R-SCE-5218920|ensemblfungi:YJL058C(gene)|ensemblfungi:YJL058C_mRNA(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005737"(cytoplasm)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0031932"(TORC2 complex)|go:"GO:0038203"(TORC2 signaling)|go:"GO:0071944"(cell periphery)|interpro:IPR013745(HbrB-like)|reactome:R-SCE-6804757	intact:EBI-751983(isoform-parent)|uniprotkb:Q9UJV3-2(isoform-parent)|ensembl:ENSG00000080561(gene)|ensembl:ENST00000443968(transcript)	-	crc64:99F0F96840311F4B	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:H+zcKwbWL90wsmvD9TfWYmEbRwM559292	rogid:/FJ+V2H7SaWon7caUWkEkmHFVxQ9606	intact-crc:0DBFA55139D3F3C0|rigid:hf9JTYnvR2caA0SqjlDsK8X6LhY	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9UJV3-2	uniprotkb:Q12056	intact:EBI-10172526|ensembl:ENSP00000413976	intact:EBI-30488|uniprotkb:D6W2T0|ensemblfungi:YOR226C	psi-mi:q9ujv3-2(display_long)|uniprotkb:RING-type E3 ubiquitin transferase MID2(gene name synonym)|uniprotkb:FXY2(gene name synonym)|uniprotkb:Midin-2(gene name synonym)|uniprotkb:Midline defect 2(gene name synonym)|uniprotkb:Midline-2(gene name synonym)|uniprotkb:RING finger protein 60(gene name synonym)|uniprotkb:RNF60(gene name synonym)|uniprotkb:TRIM1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 1(gene name synonym)|uniprotkb:MID2(gene name)|psi-mi:MID2(display_short)	psi-mi:isu2_yeast(display_long)|uniprotkb:Iron sulfur cluster scaffold protein 2(gene name synonym)|uniprotkb:ISU2(gene name)|psi-mi:ISU2(display_short)|uniprotkb:NUA2(gene name synonym)|uniprotkb:YOR226C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554872|imex:IM-24995-4289	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-751983(isoform-parent)|uniprotkb:Q9UJV3-2(isoform-parent)|ensembl:ENSG00000080561(gene)|ensembl:ENST00000443968(transcript)	sgd:S000005752|refseq:NP_014869.3|dip:DIP-4123N|ensemblfungi:YOR226C(gene)|ensemblfungi:YOR226C_mRNA(transcript)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005737"(cytoplasm)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR002871(NIF system FeS cluster assembly, NifU, N-terminal)|interpro:IPR011339(ISC system FeS cluster assembly, IscU scaffold)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:/FJ+V2H7SaWon7caUWkEkmHFVxQ9606	rogid:e4qx7ic8wpO6cTHGl73je/JVzMY559292	intact-crc:68E64F5F83EAE378|rigid:AvoXwGtX3clmjr6s4MtRim19PzA	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9UJV3-2	uniprotkb:P35184	intact:EBI-10172526|ensembl:ENSP00000413976	intact:EBI-17971|uniprotkb:D6VVU2|ensemblfungi:YIR012W	psi-mi:q9ujv3-2(display_long)|uniprotkb:RING-type E3 ubiquitin transferase MID2(gene name synonym)|uniprotkb:FXY2(gene name synonym)|uniprotkb:Midin-2(gene name synonym)|uniprotkb:Midline defect 2(gene name synonym)|uniprotkb:Midline-2(gene name synonym)|uniprotkb:RING finger protein 60(gene name synonym)|uniprotkb:RNF60(gene name synonym)|uniprotkb:TRIM1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 1(gene name synonym)|uniprotkb:MID2(gene name)|psi-mi:MID2(display_short)	psi-mi:sqt1_yeast(display_long)|uniprotkb:YIB12W(orf name)|uniprotkb:YIR012W(locus name)|uniprotkb:SQT1(gene name)|psi-mi:SQT1(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554880|imex:IM-24995-4291	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-751983(isoform-parent)|uniprotkb:Q9UJV3-2(isoform-parent)|ensembl:ENSG00000080561(gene)|ensembl:ENST00000443968(transcript)	refseq:NP_012277.1|sgd:S000001451|ensemblfungi:YIR012W_mRNA(transcript)|ensemblfungi:YIR012W(gene)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|rcsb pdb:4ZOV|rcsb pdb:4ZOX|rcsb pdb:5AMS|dip:DIP-2508N|mint:P35184	-	-	crc64:981D566076B0C881	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:/FJ+V2H7SaWon7caUWkEkmHFVxQ9606	rogid:u/Q5uAjR85ZD3op0nHiN20IVCLY559292	intact-crc:0D423B993A05DF4F|rigid:SKAxlSi558MbzGjE3wZvuhoaL34	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P15732	uniprotkb:Q9UJV3-2	intact:EBI-2097669|uniprotkb:D6VS45|ensemblfungi:YDR059C	intact:EBI-10172526|ensembl:ENSP00000413976	psi-mi:ubc5_yeast(display_long)|uniprotkb:UBC5(gene name)|psi-mi:UBC5(display_short)|uniprotkb:Ubiquitin-protein ligase(gene name synonym)|uniprotkb:Ubiquitin carrier protein(gene name synonym)|uniprotkb:YD9609.13C(orf name)|uniprotkb:D4234(orf name)|uniprotkb:YDR059C(locus name)|uniprotkb:E2 ubiquitin-conjugating enzyme 5(gene name synonym)	psi-mi:q9ujv3-2(display_long)|uniprotkb:RING-type E3 ubiquitin transferase MID2(gene name synonym)|uniprotkb:FXY2(gene name synonym)|uniprotkb:Midin-2(gene name synonym)|uniprotkb:Midline defect 2(gene name synonym)|uniprotkb:Midline-2(gene name synonym)|uniprotkb:RING finger protein 60(gene name synonym)|uniprotkb:RNF60(gene name synonym)|uniprotkb:TRIM1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 1(gene name synonym)|uniprotkb:MID2(gene name)|psi-mi:MID2(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554904|imex:IM-24995-4297	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010344.1|sgd:S000002466|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR023313|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|mint:P15732|ensemblfungi:YDR059C(gene)|ensemblfungi:YDR059C_mRNA(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034605"(cellular response to heat)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070628"(proteasome binding)|reactome:R-SCE-8866652|reactome:R-SCE-8866654|reactome:R-SCE-9033241|reactome:R-SCE-983168	intact:EBI-751983(isoform-parent)|uniprotkb:Q9UJV3-2(isoform-parent)|ensembl:ENSG00000080561(gene)|ensembl:ENST00000443968(transcript)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:lhkS9orGIZV1O+L0mEfzlpRvgtk559292	rogid:/FJ+V2H7SaWon7caUWkEkmHFVxQ9606	intact-crc:1FDF576CE0667D8B|rigid:7Oh3b3p86ZEAyVjJqseGj5X4AeE	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P20053	uniprotkb:Q9UJV3-2	intact:EBI-219|uniprotkb:D6W4H8|ensemblfungi:YPR178W	intact:EBI-10172526|ensembl:ENSP00000413976	psi-mi:prp4_yeast(display_long)|uniprotkb:PRP4(gene name)|psi-mi:PRP4(display_short)|uniprotkb:RNA4(gene name synonym)|uniprotkb:YPR178W(locus name)|uniprotkb:P9705.6(orf name)|uniprotkb:Pre-mRNA-processing protein 4(gene name synonym)	psi-mi:q9ujv3-2(display_long)|uniprotkb:RING-type E3 ubiquitin transferase MID2(gene name synonym)|uniprotkb:FXY2(gene name synonym)|uniprotkb:Midin-2(gene name synonym)|uniprotkb:Midline defect 2(gene name synonym)|uniprotkb:Midline-2(gene name synonym)|uniprotkb:RING finger protein 60(gene name synonym)|uniprotkb:RNF60(gene name synonym)|uniprotkb:TRIM1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 1(gene name synonym)|uniprotkb:MID2(gene name)|psi-mi:MID2(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554892|imex:IM-24995-4294	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015504.1|sgd:S000006382|mint:P20053|dip:DIP-2607N|ensemblfungi:YPR178W(gene)|ensemblfungi:YPR178W_mRNA(transcript)|go:"GO:0000393"(spliceosomal conformational changes to generate catalytic conformation)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0030621"(U4 snRNA binding)|go:"GO:0034247"(snoRNA splicing)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR014906("Pre-mRNA processing factor 4 (PRP4) like")|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|rcsb pdb:3JCM|rcsb pdb:5GAN|rcsb pdb:5GAP|rcsb pdb:5NRL|rcsb pdb:5ZWM|rcsb pdb:5ZWO	intact:EBI-751983(isoform-parent)|uniprotkb:Q9UJV3-2(isoform-parent)|ensembl:ENSG00000080561(gene)|ensembl:ENST00000443968(transcript)	-	crc64:7CCCA3A92AC0CE78	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:vvz5G0rqqyrugTvAPelDKit9FpQ559292	rogid:/FJ+V2H7SaWon7caUWkEkmHFVxQ9606	intact-crc:875E215134744AE4|rigid:Y29ymQkU+f+NbtmdHZNAvPot/9U	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9UJV3-2	uniprotkb:Q06411	intact:EBI-10172526|ensembl:ENSP00000413976	intact:EBI-576|uniprotkb:D6VZ60|ensemblfungi:YLR424W	psi-mi:q9ujv3-2(display_long)|uniprotkb:RING-type E3 ubiquitin transferase MID2(gene name synonym)|uniprotkb:FXY2(gene name synonym)|uniprotkb:Midin-2(gene name synonym)|uniprotkb:Midline defect 2(gene name synonym)|uniprotkb:Midline-2(gene name synonym)|uniprotkb:RING finger protein 60(gene name synonym)|uniprotkb:RNF60(gene name synonym)|uniprotkb:TRIM1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 1(gene name synonym)|uniprotkb:MID2(gene name)|psi-mi:MID2(display_short)	psi-mi:sp382_yeast(display_long)|uniprotkb:NTR1(gene name synonym)|uniprotkb:YLR424W(locus name)|uniprotkb:SPP382(gene name)|psi-mi:SPP382(display_short)|uniprotkb:CCF8(gene name synonym)|uniprotkb:Suppressor of PRP38 protein 2(gene name synonym)|uniprotkb:Nineteen complex-related protein 1(gene name synonym)|uniprotkb:CLF1 complex factor 8(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554896|imex:IM-24995-4295	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-751983(isoform-parent)|uniprotkb:Q9UJV3-2(isoform-parent)|ensembl:ENSG00000080561(gene)|ensembl:ENST00000443968(transcript)	refseq:NP_013528.1|sgd:S000004416|dip:DIP-1491N|mint:Q06411|ensemblfungi:YLR424W(gene)|ensemblfungi:YLR424W_mRNA(transcript)|go:"GO:0000349"(generation of catalytic spliceosome for first transesterification step)|go:"GO:0000390"(spliceosomal complex disassembly)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0071008"(U2-type post-mRNA release spliceosomal complex)|go:"GO:1904876"(negative regulation of DNA ligase activity)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR000467(D111/G-patch)|rcsb pdb:5Y88	-	-	crc64:9986B547B9582338	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:/FJ+V2H7SaWon7caUWkEkmHFVxQ9606	rogid:HrG54vTE2zs7jxPSzi+9eeA23/k559292	intact-crc:509CCEAC168DEB91|rigid:aCrhFYu1TtUd69F8tpEKOaWJIBc	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P40454	uniprotkb:Q9UJV3-2	intact:EBI-25278|uniprotkb:D6VVD4|ensemblfungi:YIL153W	intact:EBI-10172526|ensembl:ENSP00000413976	psi-mi:ptpa1_yeast(display_long)|uniprotkb:YIL153W(locus name)|uniprotkb:RRD1(gene name)|psi-mi:RRD1(display_short)|uniprotkb:NCS1(gene name synonym)|uniprotkb:YPA1(gene name synonym)|uniprotkb:Peptidyl-prolyl cis-trans isomerase PTPA-1(gene name synonym)|uniprotkb:Phosphotyrosyl phosphatase activator 1(gene name synonym)	psi-mi:q9ujv3-2(display_long)|uniprotkb:RING-type E3 ubiquitin transferase MID2(gene name synonym)|uniprotkb:FXY2(gene name synonym)|uniprotkb:Midin-2(gene name synonym)|uniprotkb:Midline defect 2(gene name synonym)|uniprotkb:Midline-2(gene name synonym)|uniprotkb:RING finger protein 60(gene name synonym)|uniprotkb:RNF60(gene name synonym)|uniprotkb:TRIM1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 1(gene name synonym)|uniprotkb:MID2(gene name)|psi-mi:MID2(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554900|imex:IM-24995-4296	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012113.1|sgd:S000001415|mint:P40454|dip:DIP-5663N|ensemblfungi:YIL153W(gene)|ensemblfungi:YIL153W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006914"(autophagy)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008160"(protein tyrosine phosphatase activator activity)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0043618"(regulation of transcription from RNA polymerase II promoter in response to stress)|interpro:IPR004327(Phosphotyrosyl phosphatase activator, PTPA)|interpro:IPR037218|interpro:IPR043170|rcsb pdb:2IXO|rcsb pdb:2IXP	intact:EBI-751983(isoform-parent)|uniprotkb:Q9UJV3-2(isoform-parent)|ensembl:ENSG00000080561(gene)|ensembl:ENST00000443968(transcript)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:It2q8WlpmvLEZ1fqpRF5Fypw9Q4559292	rogid:/FJ+V2H7SaWon7caUWkEkmHFVxQ9606	intact-crc:3E865E557BC6AEC3|rigid:CcpVbbc0xfEqFA2I3Oq4E/m04K8	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P38770	uniprotkb:Q9UJW9	intact:EBI-24507|uniprotkb:D3DKY3|ensemblfungi:YHR036W	intact:EBI-748621|uniprotkb:Q96CQ2|uniprotkb:B3KQB3|ensembl:ENSP00000325414|ensembl:ENSP00000375882	psi-mi:brl1_yeast(display_long)|uniprotkb:BRL1(gene name)|psi-mi:BRL1(display_short)|uniprotkb:BRR6-like protein 1(gene name synonym)|uniprotkb:YHR036W(locus name)	psi-mi:srtd3_human(display_long)|uniprotkb:Replication protein-binding trans-activator(gene name synonym)|uniprotkb:SERTAD3(gene name)|psi-mi:SERTAD3(display_short)|uniprotkb:RBT1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554928|imex:IM-24995-4303	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011901.1|sgd:S000001078|dip:DIP-5580N|mint:P38770|ensemblfungi:YHR036W(gene)|ensemblfungi:YHR036W_mRNA(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006998"(nuclear envelope organization)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0051028"(mRNA transport)|go:"GO:0055088"(lipid homeostasis)|interpro:IPR018767|interpro:IPR040202	refseq:XP_006723242.1|refseq:NP_037500.2|refseq:NP_976219.1|refseq:XP_005258889.1|ensembl:ENSG00000167565(gene)|ensembl:ENST00000322354(transcript)|ensembl:ENST00000392028(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR009263(SERTA)|interpro:IPR039585	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:gLJXF3VREvr8+oW8HZYTfHDho4A559292	rogid:zraVKcqHA7SNRrMV50iyPK6O7ok9606	intact-crc:48AED466503563B6|rigid:PAl3pboTff33jepoEJ8ViVlEyUk	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9UJW9	uniprotkb:Q04307	intact:EBI-748621|uniprotkb:Q96CQ2|uniprotkb:B3KQB3|ensembl:ENSP00000325414|ensembl:ENSP00000375882	intact:EBI-15858|uniprotkb:Q2VQW5|ensemblfungi:YDR045C|uniprotkb:D6VS33	psi-mi:srtd3_human(display_long)|uniprotkb:Replication protein-binding trans-activator(gene name synonym)|uniprotkb:SERTAD3(gene name)|psi-mi:SERTAD3(display_short)|uniprotkb:RBT1(gene name synonym)	psi-mi:rpc10_yeast(display_long)|uniprotkb:RPC11(gene name)|psi-mi:RPC11(display_short)|uniprotkb:YDR045C(locus name)|uniprotkb:YD9609.01C(orf name)|uniprotkb:RNA polymerase III subunit C11(gene name synonym)|uniprotkb:DNA-directed RNA polymerases III 12.5 kDa polypeptide(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554924|imex:IM-24995-4302	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006723242.1|refseq:NP_037500.2|refseq:NP_976219.1|refseq:XP_005258889.1|ensembl:ENSG00000167565(gene)|ensembl:ENST00000322354(transcript)|ensembl:ENST00000392028(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR009263(SERTA)|interpro:IPR039585	ensemblfungi:YDR045C(gene)|refseq:NP_010330.1|sgd:S000002452|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006386"(termination of RNA polymerase III transcription)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042779"(tRNA 3'-trailer cleavage)|go:"GO:0042797"(tRNA transcription by RNA polymerase III)|interpro:IPR001222(Zinc finger, TFIIS-type)|interpro:IPR001529(DNA-directed RNA polymerase, M/15 kDa subunit)|interpro:IPR012164(DNA-directed RNA polymerase, subunit C11/M/9)|interpro:IPR019761|interpro:IPR034014|rcsb pdb:3QT1|ensemblfungi:YDR045C_mRNA(transcript)|rcsb pdb:5FJ8|rcsb pdb:5FJ9|rcsb pdb:5FJA|rcsb pdb:6CNB|rcsb pdb:6CNC|rcsb pdb:6CND|rcsb pdb:6CNF|rcsb pdb:6EU0|rcsb pdb:6EU2|rcsb pdb:6EU3|rcsb pdb:6F40|rcsb pdb:6F41|rcsb pdb:6F42|rcsb pdb:6F44|rcsb pdb:6TUT|reactome:R-SCE-76061|reactome:R-SCE-76066|rcsb pdb:6EU1|dip:DIP-887N|mint:Q04307	-	-	crc64:E4AA802EC9F92230	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:zraVKcqHA7SNRrMV50iyPK6O7ok9606	rogid:G2fIQbptabHIUI224iPtTJF+dIs559292	intact-crc:2B8E3B7AE8614E37|rigid:MzT3LybxicBeAZjMmgwBKUpdDGo	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P53038	uniprotkb:Q9UJV3-2	intact:EBI-19106|uniprotkb:D6VUN1|ensemblfungi:YGR099W	intact:EBI-10172526|ensembl:ENSP00000413976	psi-mi:tel2_yeast(display_long)|uniprotkb:YGR099W(locus name)|uniprotkb:TEL2(gene name)|psi-mi:TEL2(display_short)	psi-mi:q9ujv3-2(display_long)|uniprotkb:RING-type E3 ubiquitin transferase MID2(gene name synonym)|uniprotkb:FXY2(gene name synonym)|uniprotkb:Midin-2(gene name synonym)|uniprotkb:Midline defect 2(gene name synonym)|uniprotkb:Midline-2(gene name synonym)|uniprotkb:RING finger protein 60(gene name synonym)|uniprotkb:RNF60(gene name synonym)|uniprotkb:TRIM1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 1(gene name synonym)|uniprotkb:MID2(gene name)|psi-mi:MID2(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554908|imex:IM-24995-4298	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003331|ensemblfungi:YGR099W(gene)|ensemblfungi:YGR099W_mRNA(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0005829"(cytosol)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0034502"(protein localization to chromosome)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0070209"(ASTRA complex)|interpro:IPR019337|interpro:IPR038528|rcsb pdb:3O4Z|refseq:NP_011613.3|dip:DIP-1245N|mint:P53038	intact:EBI-751983(isoform-parent)|uniprotkb:Q9UJV3-2(isoform-parent)|ensembl:ENSG00000080561(gene)|ensembl:ENST00000443968(transcript)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:SZibPBili0M8YgHIwxf+sKkLk+M559292	rogid:/FJ+V2H7SaWon7caUWkEkmHFVxQ9606	intact-crc:E5BD4520AB1E9C59|rigid:six8sufYSUVN6LDhYbISxep+gaM	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9UJV3-2	uniprotkb:P38260	intact:EBI-10172526|ensembl:ENSP00000413976	intact:EBI-21563|uniprotkb:D6VQA0|ensemblfungi:YBR101C	psi-mi:q9ujv3-2(display_long)|uniprotkb:RING-type E3 ubiquitin transferase MID2(gene name synonym)|uniprotkb:FXY2(gene name synonym)|uniprotkb:Midin-2(gene name synonym)|uniprotkb:Midline defect 2(gene name synonym)|uniprotkb:Midline-2(gene name synonym)|uniprotkb:RING finger protein 60(gene name synonym)|uniprotkb:RNF60(gene name synonym)|uniprotkb:TRIM1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 1(gene name synonym)|uniprotkb:MID2(gene name)|psi-mi:MID2(display_short)	psi-mi:fes1_yeast(display_long)|uniprotkb:YBR101C(locus name)|uniprotkb:YBR0830(orf name)|uniprotkb:Factor exchange for SSA1 protein 1(gene name synonym)|uniprotkb:FES1(gene name)|psi-mi:FES1(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554916|imex:IM-24995-4300	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-751983(isoform-parent)|uniprotkb:Q9UJV3-2(isoform-parent)|ensembl:ENSG00000080561(gene)|ensembl:ENST00000443968(transcript)	sgd:S000000305|refseq:NP_009659.3|mint:P38260|dip:DIP-4918N|ensemblfungi:YBR101C(gene)|ensemblfungi:YBR101C_mRNA(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006417"(regulation of translation)|go:"GO:0071629"(cytoplasm protein quality control by the ubiquitin-proteasome system)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013918(Nucleotide exchange factor Fes1)|interpro:IPR016024(Armadillo-type fold)	-	-	crc64:4A50D069625BA500	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:/FJ+V2H7SaWon7caUWkEkmHFVxQ9606	rogid:swXhGbIfsVTGs+eOqqViPwySpI0559292	intact-crc:9B17326328C200F7|rigid:qDyPLF8u93/d6IjBmA8FV6aV7CI	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P32502	uniprotkb:Q9UJV3-2	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	intact:EBI-10172526|ensembl:ENSP00000413976	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:q9ujv3-2(display_long)|uniprotkb:RING-type E3 ubiquitin transferase MID2(gene name synonym)|uniprotkb:FXY2(gene name synonym)|uniprotkb:Midin-2(gene name synonym)|uniprotkb:Midline defect 2(gene name synonym)|uniprotkb:Midline-2(gene name synonym)|uniprotkb:RING finger protein 60(gene name synonym)|uniprotkb:RNF60(gene name synonym)|uniprotkb:TRIM1(gene name synonym)|uniprotkb:Tripartite motif-containing protein 1(gene name synonym)|uniprotkb:MID2(gene name)|psi-mi:MID2(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554912|imex:IM-24995-4299	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731	intact:EBI-751983(isoform-parent)|uniprotkb:Q9UJV3-2(isoform-parent)|ensembl:ENSG00000080561(gene)|ensembl:ENST00000443968(transcript)	-	crc64:A5409FAF1594854C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	rogid:/FJ+V2H7SaWon7caUWkEkmHFVxQ9606	intact-crc:731CFC2243E3E5D1|rigid:gLKZX2c9WnbLhrFzr0iSTW6taIU	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9UJW9	uniprotkb:P47086	intact:EBI-748621|uniprotkb:Q96CQ2|uniprotkb:B3KQB3|ensembl:ENSP00000325414|ensembl:ENSP00000375882	intact:EBI-26299|uniprotkb:D6VWI7|uniprotkb:Q6Q5N5|ensemblfungi:YJR011C	psi-mi:srtd3_human(display_long)|uniprotkb:Replication protein-binding trans-activator(gene name synonym)|uniprotkb:SERTAD3(gene name)|psi-mi:SERTAD3(display_short)|uniprotkb:RBT1(gene name synonym)	psi-mi:yjy1_yeast(display_long)|uniprotkb:J1438(orf name)|uniprotkb:YJR83.26(orf name)|uniprotkb:YJR011C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554920|imex:IM-24995-4301	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006723242.1|refseq:NP_037500.2|refseq:NP_976219.1|refseq:XP_005258889.1|ensembl:ENSG00000167565(gene)|ensembl:ENST00000322354(transcript)|ensembl:ENST00000392028(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR009263(SERTA)|interpro:IPR039585	sgd:S000003772|refseq:NP_012545.1|mint:P47086|dip:DIP-5694N|ensemblfungi:YJR011C(gene)|ensemblfungi:YJR011C_mRNA(transcript)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:zraVKcqHA7SNRrMV50iyPK6O7ok9606	rogid:b7YXohJEN6FMN8gYKAKboZQkxvQ559292	intact-crc:2B1729BAA98077AA|rigid:lPET/7vwNIdmGxP+T7v5gnf7vjE	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9UKT9	uniprotkb:P06782	intact:EBI-747204|uniprotkb:Q8WWQ9|uniprotkb:Q8WWR0|uniprotkb:Q8WWR1|uniprotkb:Q8WWR2|uniprotkb:Q8WWR3|uniprotkb:Q8N574|uniprotkb:B4DVV5|uniprotkb:Q69BL6|uniprotkb:Q69BL7|uniprotkb:Q69BL8|uniprotkb:Q69BL9|uniprotkb:Q69BM0|uniprotkb:Q69BM1|uniprotkb:Q69BM2|uniprotkb:Q69BM3|uniprotkb:Q69BM5|ensembl:ENSP00000344544	intact:EBI-17516|uniprotkb:D6VTA0|ensemblfungi:YDR477W	psi-mi:ikzf3_human(display_long)|uniprotkb:ZNFN1A3(gene name synonym)|uniprotkb:Ikaros family zinc finger protein 3(gene name synonym)|uniprotkb:IKZF3(gene name)|psi-mi:IKZF3(display_short)	psi-mi:snf1_yeast(display_long)|uniprotkb:SNF1(gene name)|psi-mi:SNF1(display_short)|uniprotkb:CAT1(gene name synonym)|uniprotkb:CCR1(gene name synonym)|uniprotkb:GLC2(gene name synonym)|uniprotkb:PAS14(gene name synonym)|uniprotkb:Sucrose nonfermentating protein 1(gene name synonym)|uniprotkb:D8035.20(orf name)|uniprotkb:YDR477W(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554948|imex:IM-24995-4308	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001271443.1|refseq:NP_001271444.1|refseq:NP_036613.2|refseq:NP_899051.1|refseq:NP_899052.1|refseq:NP_899053.1|refseq:NP_899054.1|refseq:NP_899055.1|refseq:NP_001271445.1|refseq:NP_001244337.1|refseq:NP_001244338.1|refseq:NP_001244339.1|refseq:NP_001244340.1|refseq:NP_001244341.1|refseq:NP_001244342.1|refseq:NP_001244343.1|ensembl:ENSG00000161405(gene)|ensembl:ENST00000346872(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007498"(mesoderm development)|go:"GO:0009617"(response to bacterium)|go:"GO:0030888"(regulation of B cell proliferation)|go:"GO:0042113"(B cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045577"(regulation of B cell differentiation)|go:"GO:0045619"(regulation of lymphocyte differentiation)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|go:"GO:0046872"(metal ion binding)|dip:DIP-56975N	refseq:NP_010765.3|sgd:S000002885|ensemblfungi:YDR477W(gene)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0071940"(fungal-type cell wall assembly)|go:"GO:0090606"(single-species surface biofilm formation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900436"(positive regulation of filamentous growth of a population of unicellular organisms in response to starvation)|go:"GO:2000222"(positive regulation of pseudohyphal growth)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013896(Ubiquitin-associated region 2)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR028375|interpro:IPR032270|rcsb pdb:2FH9|rcsb pdb:2QLV|rcsb pdb:3DAE|rcsb pdb:3HYH|rcsb pdb:3MN3|rcsb pdb:3T4N|rcsb pdb:3TDH|rcsb pdb:3TE5|reactome:R-SCE-1632852|reactome:R-SCE-163680|reactome:R-SCE-200425|reactome:R-SCE-380972|ensemblfungi:YDR477W_mRNA(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000144"(cellular bud neck septin ring)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004679"(AMP-activated protein kinase activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005641"(nuclear envelope lumen)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0007155"(cell adhesion)|go:"GO:0016239"(positive regulation of macroautophagy)|dip:DIP-18N|mint:P06782	-	-	crc64:F5C63565C986C4E3	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:2Kp6LefSLfK5VIiE6DmQusFIfMY9606	rogid:O/SAW1kJE3fpoXPHGLG01i9RePs559292	intact-crc:2A0F4A6B2B7125AF|rigid:lqfFs/MV9M4ricnpIgL3cu1sG64	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9UKT9	uniprotkb:P47041	intact:EBI-747204|uniprotkb:Q8WWQ9|uniprotkb:Q8WWR0|uniprotkb:Q8WWR1|uniprotkb:Q8WWR2|uniprotkb:Q8WWR3|uniprotkb:Q8N574|uniprotkb:B4DVV5|uniprotkb:Q69BL6|uniprotkb:Q69BL7|uniprotkb:Q69BL8|uniprotkb:Q69BL9|uniprotkb:Q69BM0|uniprotkb:Q69BM1|uniprotkb:Q69BM2|uniprotkb:Q69BM3|uniprotkb:Q69BM5|ensembl:ENSP00000344544	intact:EBI-25889|uniprotkb:D6VWC4|ensemblfungi:YJL058C	psi-mi:ikzf3_human(display_long)|uniprotkb:ZNFN1A3(gene name synonym)|uniprotkb:Ikaros family zinc finger protein 3(gene name synonym)|uniprotkb:IKZF3(gene name)|psi-mi:IKZF3(display_short)	psi-mi:bit61_yeast(display_long)|uniprotkb:YJL058C(locus name)|uniprotkb:J1141(orf name)|uniprotkb:61 kDa binding partner of TOR2 protein(gene name synonym)|uniprotkb:BIT61(gene name)|psi-mi:BIT61(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554944|imex:IM-24995-4307	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001271443.1|refseq:NP_001271444.1|refseq:NP_036613.2|refseq:NP_899051.1|refseq:NP_899052.1|refseq:NP_899053.1|refseq:NP_899054.1|refseq:NP_899055.1|refseq:NP_001271445.1|refseq:NP_001244337.1|refseq:NP_001244338.1|refseq:NP_001244339.1|refseq:NP_001244340.1|refseq:NP_001244341.1|refseq:NP_001244342.1|refseq:NP_001244343.1|ensembl:ENSG00000161405(gene)|ensembl:ENST00000346872(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007498"(mesoderm development)|go:"GO:0009617"(response to bacterium)|go:"GO:0030888"(regulation of B cell proliferation)|go:"GO:0042113"(B cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045577"(regulation of B cell differentiation)|go:"GO:0045619"(regulation of lymphocyte differentiation)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|go:"GO:0046872"(metal ion binding)|dip:DIP-56975N	refseq:NP_012477.1|sgd:S000003594|dip:DIP-1444N|reactome:R-SCE-1257604|reactome:R-SCE-389357|reactome:R-SCE-5218920|ensemblfungi:YJL058C(gene)|ensemblfungi:YJL058C_mRNA(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005737"(cytoplasm)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0031932"(TORC2 complex)|go:"GO:0038203"(TORC2 signaling)|go:"GO:0071944"(cell periphery)|interpro:IPR013745(HbrB-like)|reactome:R-SCE-6804757	-	-	crc64:99F0F96840311F4B	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:2Kp6LefSLfK5VIiE6DmQusFIfMY9606	rogid:H+zcKwbWL90wsmvD9TfWYmEbRwM559292	intact-crc:17434FA21A0B0CDA|rigid:Jn6qVPw1QCEseCWRZX5P5z2dM34	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9UJX2	intact:EBI-11522371	intact:EBI-396137|uniprotkb:O75433|uniprotkb:Q9BS73|uniprotkb:B4E3A2|uniprotkb:B7WP05|uniprotkb:Q53FN2|uniprotkb:A8K6E5|uniprotkb:D3DQB7|ensembl:ENSP00000378350	-	psi-mi:cdc23_human(display_long)|uniprotkb:CDC23(gene name)|psi-mi:CDC23(display_short)|uniprotkb:ANAPC8(gene name synonym)|uniprotkb:Anaphase-promoting complex subunit 8(gene name synonym)|uniprotkb:Cyclosome subunit 8(gene name synonym)	psi-mi:yjr003c(display_short)|psi-mi:EBI-11522371(display_long)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554932|imex:IM-24995-4304	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004652.2|dip:DIP-32959N|ensembl:ENSG00000094880(gene)|ensembl:ENST00000394886(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0007091"(metaphase/anaphase transition of mitotic cell cycle)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030071"(regulation of mitotic metaphase/anaphase transition)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0051301"(cell division)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR007192(Cdc23)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|mint:Q9UJX2|rcsb pdb:4UI9|rcsb pdb:5A31|rcsb pdb:5G04|rcsb pdb:5G05|rcsb pdb:5KHR|rcsb pdb:5KHU|rcsb pdb:5L9T|rcsb pdb:5L9U|rcsb pdb:5LCW|rcsb pdb:6Q6G|rcsb pdb:6Q6H|rcsb pdb:6TLJ|rcsb pdb:6TM5|rcsb pdb:6TNT|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-9687136|reactome:R-HSA-983168	-	-	-	no-uniprot-update:	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:uTZL2UHzZHLoKnio/1LcuSzZpW09606	rogid:dYGrrP3JnrXO2rj4v/nTT64la6A4932	intact-crc:6D93545C10877F6D|rigid:PDeq10RYhZ+fN+OuxIR+rI3fZWw	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P32502	uniprotkb:Q9UJX2	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	intact:EBI-396137|uniprotkb:O75433|uniprotkb:Q9BS73|uniprotkb:B4E3A2|uniprotkb:B7WP05|uniprotkb:Q53FN2|uniprotkb:A8K6E5|uniprotkb:D3DQB7|ensembl:ENSP00000378350	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:cdc23_human(display_long)|uniprotkb:CDC23(gene name)|psi-mi:CDC23(display_short)|uniprotkb:ANAPC8(gene name synonym)|uniprotkb:Anaphase-promoting complex subunit 8(gene name synonym)|uniprotkb:Cyclosome subunit 8(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554936|imex:IM-24995-4305	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731	refseq:NP_004652.2|dip:DIP-32959N|ensembl:ENSG00000094880(gene)|ensembl:ENST00000394886(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0007091"(metaphase/anaphase transition of mitotic cell cycle)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030071"(regulation of mitotic metaphase/anaphase transition)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0051301"(cell division)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR007192(Cdc23)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|mint:Q9UJX2|rcsb pdb:4UI9|rcsb pdb:5A31|rcsb pdb:5G04|rcsb pdb:5G05|rcsb pdb:5KHR|rcsb pdb:5KHU|rcsb pdb:5L9T|rcsb pdb:5L9U|rcsb pdb:5LCW|rcsb pdb:6Q6G|rcsb pdb:6Q6H|rcsb pdb:6TLJ|rcsb pdb:6TM5|rcsb pdb:6TNT|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-9687136|reactome:R-HSA-983168	-	crc64:A5409FAF1594854C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	rogid:uTZL2UHzZHLoKnio/1LcuSzZpW09606	intact-crc:05E4311AFA35EDEF|rigid:oByXm7mip5OSH18LrnwpeWvZn+U	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q08204	uniprotkb:Q9UKS7-2	intact:EBI-34125|uniprotkb:D6W231|ensemblfungi:YOL034W	intact:EBI-11536241|ensembl:ENSP00000363439	psi-mi:smc5_yeast(display_long)|uniprotkb:SMC5(gene name)|psi-mi:SMC5(display_short)|uniprotkb:YOL034W(locus name)	psi-mi:q9uks7-2(display_long)|uniprotkb:HELIOS(gene name synonym)|uniprotkb:Ikaros family zinc finger protein 2(gene name synonym)|uniprotkb:ZNFN1A2(gene name synonym)|uniprotkb:Helios 1v(isoform synonym)|uniprotkb:IKZF2(gene name)|psi-mi:IKZF2(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554940|imex:IM-24995-4306	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014608.1|sgd:S000005394|mint:Q08204|dip:DIP-1979N|ensemblfungi:YOL034W(gene)|ensemblfungi:YOL034W_mRNA(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000725"(recombinational repair)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006281"(DNA repair)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0016925"(protein sumoylation)|go:"GO:0030915"(Smc5-Smc6 complex)|go:"GO:0051304"(chromosome separation)|go:"GO:0071139"(resolution of recombination intermediates)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR027131|interpro:IPR027417|rcsb pdb:3HTK|reactome:R-SCE-3108214	intact:EBI-3893057(isoform-parent)|ensembl:ENSG00000030419(gene)|ensembl:ENST00000374319(transcript)|uniprotkb:Q9UKS7-2(isoform-parent)	-	crc64:6752B96438CFB549	isoform-comment:"Contains a glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) at position 95."	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:7EBoBNiTfotgfzhZ2+a+PcQTAqc559292	rogid:BPYW+3VwNBn9+7Qbh63ii8np0F09606	intact-crc:970E63BAA24244C2|rigid:BcCyHJrysULnVjzARp46XnwdqmM	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9UKT9	uniprotkb:P40014	intact:EBI-747204|uniprotkb:Q8WWQ9|uniprotkb:Q8WWR0|uniprotkb:Q8WWR1|uniprotkb:Q8WWR2|uniprotkb:Q8WWR3|uniprotkb:Q8N574|uniprotkb:B4DVV5|uniprotkb:Q69BL6|uniprotkb:Q69BL7|uniprotkb:Q69BL8|uniprotkb:Q69BL9|uniprotkb:Q69BM0|uniprotkb:Q69BM1|uniprotkb:Q69BM2|uniprotkb:Q69BM3|uniprotkb:Q69BM5|ensembl:ENSP00000344544	intact:EBI-22458|uniprotkb:D3DLR6|ensemblfungi:YER018C	psi-mi:ikzf3_human(display_long)|uniprotkb:ZNFN1A3(gene name synonym)|uniprotkb:Ikaros family zinc finger protein 3(gene name synonym)|uniprotkb:IKZF3(gene name)|psi-mi:IKZF3(display_short)	psi-mi:spc25_yeast(display_long)|uniprotkb:YER018C(locus name)|uniprotkb:SPC25(gene name)|psi-mi:SPC25(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554972|imex:IM-24995-4314	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001271443.1|refseq:NP_001271444.1|refseq:NP_036613.2|refseq:NP_899051.1|refseq:NP_899052.1|refseq:NP_899053.1|refseq:NP_899054.1|refseq:NP_899055.1|refseq:NP_001271445.1|refseq:NP_001244337.1|refseq:NP_001244338.1|refseq:NP_001244339.1|refseq:NP_001244340.1|refseq:NP_001244341.1|refseq:NP_001244342.1|refseq:NP_001244343.1|ensembl:ENSG00000161405(gene)|ensembl:ENST00000346872(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007498"(mesoderm development)|go:"GO:0009617"(response to bacterium)|go:"GO:0030888"(regulation of B cell proliferation)|go:"GO:0042113"(B cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045577"(regulation of B cell differentiation)|go:"GO:0045619"(regulation of lymphocyte differentiation)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|go:"GO:0046872"(metal ion binding)|dip:DIP-56975N	refseq:NP_010934.3|sgd:S000000820|dip:DIP-2990N|mint:P40014|ensemblfungi:YER018C(gene)|ensemblfungi:YER018C_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0051301"(cell division)|go:"GO:0098653"(centromere clustering)|interpro:IPR038066|rcsb pdb:2FTX|rcsb pdb:2FV4|rcsb pdb:4GEQ|rcsb pdb:5T6J|rcsb pdb:5TCS|rcsb pdb:5TD8|rcsb pdb:7KDF	-	-	crc64:1BED6CCFF330A5D8	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:2Kp6LefSLfK5VIiE6DmQusFIfMY9606	rogid:i5gKRZA7GAjnCVzuX/qP8YmpQRA559292	intact-crc:3614FE406452E85F|rigid:fjco9Hw8L8MpKcC5f63nO4QBPYE	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9UKT9	uniprotkb:P23059	intact:EBI-747204|uniprotkb:Q8WWQ9|uniprotkb:Q8WWR0|uniprotkb:Q8WWR1|uniprotkb:Q8WWR2|uniprotkb:Q8WWR3|uniprotkb:Q8N574|uniprotkb:B4DVV5|uniprotkb:Q69BL6|uniprotkb:Q69BL7|uniprotkb:Q69BL8|uniprotkb:Q69BL9|uniprotkb:Q69BM0|uniprotkb:Q69BM1|uniprotkb:Q69BM2|uniprotkb:Q69BM3|uniprotkb:Q69BM5|ensembl:ENSP00000344544	intact:EBI-10950|ensemblfungi:YCR020C-A|uniprotkb:D6VR29	psi-mi:ikzf3_human(display_long)|uniprotkb:ZNFN1A3(gene name synonym)|uniprotkb:Ikaros family zinc finger protein 3(gene name synonym)|uniprotkb:IKZF3(gene name)|psi-mi:IKZF3(display_short)	psi-mi:naa38_yeast(display_long)|uniprotkb:MAK31(gene name)|psi-mi:MAK31(display_short)|uniprotkb:YCR020C-A(locus name)|uniprotkb:YCR20C-A(orf name)|uniprotkb:L-A virus GAG protein N-acetyltransferase subunit MAK31(gene name synonym)|uniprotkb:Maintenance of killer protein 31(gene name synonym)|uniprotkb:NAA38(gene name synonym)|uniprotkb:N-terminal acetyltransferase C complex subunit MAK31(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554968|imex:IM-24995-4313	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001271443.1|refseq:NP_001271444.1|refseq:NP_036613.2|refseq:NP_899051.1|refseq:NP_899052.1|refseq:NP_899053.1|refseq:NP_899054.1|refseq:NP_899055.1|refseq:NP_001271445.1|refseq:NP_001244337.1|refseq:NP_001244338.1|refseq:NP_001244339.1|refseq:NP_001244340.1|refseq:NP_001244341.1|refseq:NP_001244342.1|refseq:NP_001244343.1|ensembl:ENSG00000161405(gene)|ensembl:ENST00000346872(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007498"(mesoderm development)|go:"GO:0009617"(response to bacterium)|go:"GO:0030888"(regulation of B cell proliferation)|go:"GO:0042113"(B cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045577"(regulation of B cell differentiation)|go:"GO:0045619"(regulation of lymphocyte differentiation)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|go:"GO:0046872"(metal ion binding)|dip:DIP-56975N	ensemblfungi:YCR020C-A(gene)|ensemblfungi:YCR020C-A_mRNA(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005688"(U6 snRNP)|go:"GO:0005829"(cytosol)|go:"GO:0006474"(N-terminal protein amino acid acetylation)|go:"GO:0016070"(RNA metabolic process)|go:"GO:0031417"(NatC complex)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071011"(precatalytic spliceosome)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR034110|rcsb pdb:6YGA|rcsb pdb:6YGB|rcsb pdb:6YGC|rcsb pdb:6YGD|refseq:NP_009948.1|sgd:S000000614|mint:P23059|dip:DIP-1429N	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:2Kp6LefSLfK5VIiE6DmQusFIfMY9606	rogid:VUwG0xxj0NeyZKANRYCAgJGuqs8559292	intact-crc:AAF1588BDD4FF30B|rigid:7/DvT/1dtf1pZQqfsZaJOCyhnUI	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q02831	uniprotkb:Q9UKT9	intact:EBI-31828|uniprotkb:D6W3T9|ensemblfungi:YPL077C	intact:EBI-747204|uniprotkb:Q8WWQ9|uniprotkb:Q8WWR0|uniprotkb:Q8WWR1|uniprotkb:Q8WWR2|uniprotkb:Q8WWR3|uniprotkb:Q8N574|uniprotkb:B4DVV5|uniprotkb:Q69BL6|uniprotkb:Q69BL7|uniprotkb:Q69BL8|uniprotkb:Q69BL9|uniprotkb:Q69BM0|uniprotkb:Q69BM1|uniprotkb:Q69BM2|uniprotkb:Q69BM3|uniprotkb:Q69BM5|ensembl:ENSP00000344544	psi-mi:yp077_yeast(display_long)|uniprotkb:YPL077C(locus name)	psi-mi:ikzf3_human(display_long)|uniprotkb:ZNFN1A3(gene name synonym)|uniprotkb:Ikaros family zinc finger protein 3(gene name synonym)|uniprotkb:IKZF3(gene name)|psi-mi:IKZF3(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554952|imex:IM-24995-4309	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005998|refseq:NP_015248.1|dip:DIP-4022N|ensemblfungi:YPL077C(gene)|ensemblfungi:YPL077C_mRNA(transcript)	refseq:NP_001271443.1|refseq:NP_001271444.1|refseq:NP_036613.2|refseq:NP_899051.1|refseq:NP_899052.1|refseq:NP_899053.1|refseq:NP_899054.1|refseq:NP_899055.1|refseq:NP_001271445.1|refseq:NP_001244337.1|refseq:NP_001244338.1|refseq:NP_001244339.1|refseq:NP_001244340.1|refseq:NP_001244341.1|refseq:NP_001244342.1|refseq:NP_001244343.1|ensembl:ENSG00000161405(gene)|ensembl:ENST00000346872(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007498"(mesoderm development)|go:"GO:0009617"(response to bacterium)|go:"GO:0030888"(regulation of B cell proliferation)|go:"GO:0042113"(B cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045577"(regulation of B cell differentiation)|go:"GO:0045619"(regulation of lymphocyte differentiation)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|go:"GO:0046872"(metal ion binding)|dip:DIP-56975N	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:yqOn4GWKNmFZ7UvGmyBEpgoyKlA559292	rogid:2Kp6LefSLfK5VIiE6DmQusFIfMY9606	intact-crc:0FF697104DB889AD|rigid:oScBJtu7xWOjgUIb5f5LQdYTiGI	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9UKT9	uniprotkb:P38261	intact:EBI-747204|uniprotkb:Q8WWQ9|uniprotkb:Q8WWR0|uniprotkb:Q8WWR1|uniprotkb:Q8WWR2|uniprotkb:Q8WWR3|uniprotkb:Q8N574|uniprotkb:B4DVV5|uniprotkb:Q69BL6|uniprotkb:Q69BL7|uniprotkb:Q69BL8|uniprotkb:Q69BL9|uniprotkb:Q69BM0|uniprotkb:Q69BM1|uniprotkb:Q69BM2|uniprotkb:Q69BM3|uniprotkb:Q69BM5|ensembl:ENSP00000344544	intact:EBI-21567|uniprotkb:D6VQA1|ensemblfungi:YBR102C	psi-mi:ikzf3_human(display_long)|uniprotkb:ZNFN1A3(gene name synonym)|uniprotkb:Ikaros family zinc finger protein 3(gene name synonym)|uniprotkb:IKZF3(gene name)|psi-mi:IKZF3(display_short)	psi-mi:exo84_yeast(display_long)|uniprotkb:YBR102C(locus name)|uniprotkb:YBR0831(orf name)|uniprotkb:Exocyst complex protein of 84 kDa(gene name synonym)|uniprotkb:EXO84(gene name)|psi-mi:EXO84(display_short)|uniprotkb:USA3(gene name synonym)|uniprotkb:U1 SNP1-associating protein 3(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554960|imex:IM-24995-4311	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001271443.1|refseq:NP_001271444.1|refseq:NP_036613.2|refseq:NP_899051.1|refseq:NP_899052.1|refseq:NP_899053.1|refseq:NP_899054.1|refseq:NP_899055.1|refseq:NP_001271445.1|refseq:NP_001244337.1|refseq:NP_001244338.1|refseq:NP_001244339.1|refseq:NP_001244340.1|refseq:NP_001244341.1|refseq:NP_001244342.1|refseq:NP_001244343.1|ensembl:ENSG00000161405(gene)|ensembl:ENST00000346872(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007498"(mesoderm development)|go:"GO:0009617"(response to bacterium)|go:"GO:0030888"(regulation of B cell proliferation)|go:"GO:0042113"(B cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045577"(regulation of B cell differentiation)|go:"GO:0045619"(regulation of lymphocyte differentiation)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|go:"GO:0046872"(metal ion binding)|dip:DIP-56975N	refseq:NP_009660.1|sgd:S000000306|mint:P38261|dip:DIP-2732N|ensemblfungi:YBR102C(gene)|ensemblfungi:YBR102C_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0000145"(exocyst)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0001927"(exocyst assembly)|go:"GO:0005628"(prospore membrane)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0008104"(protein localization)|go:"GO:0015031"(protein transport)|go:"GO:0030133"(transport vesicle)|go:"GO:0043332"(mating projection tip)|go:"GO:0051601"(exocyst localization)|go:"GO:0090522"(vesicle tethering involved in exocytosis)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR032403|interpro:IPR033961|interpro:IPR042560|interpro:IPR042561|rcsb pdb:2D2S|rcsb pdb:5YFP|rcsb pdb:6VKL|reactome:R-SCE-264876	-	-	crc64:1BCDE834466C3536	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:2Kp6LefSLfK5VIiE6DmQusFIfMY9606	rogid:tJ29//zd8m0QGJu94oH597pBVTg559292	intact-crc:F850C56EBA6A2AB3|rigid:vWYb+BjNTJ6s0RM+v9zw/HiC52w	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P53286	uniprotkb:Q9UKT9	intact:EBI-3796|uniprotkb:D6VUS2|ensemblfungi:YGR142W	intact:EBI-747204|uniprotkb:Q8WWQ9|uniprotkb:Q8WWR0|uniprotkb:Q8WWR1|uniprotkb:Q8WWR2|uniprotkb:Q8WWR3|uniprotkb:Q8N574|uniprotkb:B4DVV5|uniprotkb:Q69BL6|uniprotkb:Q69BL7|uniprotkb:Q69BL8|uniprotkb:Q69BL9|uniprotkb:Q69BM0|uniprotkb:Q69BM1|uniprotkb:Q69BM2|uniprotkb:Q69BM3|uniprotkb:Q69BM5|ensembl:ENSP00000344544	psi-mi:btn2_yeast(display_long)|uniprotkb:YGR142W(locus name)|uniprotkb:BTN2(gene name)|psi-mi:BTN2(display_short)|uniprotkb:Batten disease protein 2(gene name synonym)	psi-mi:ikzf3_human(display_long)|uniprotkb:ZNFN1A3(gene name synonym)|uniprotkb:Ikaros family zinc finger protein 3(gene name synonym)|uniprotkb:IKZF3(gene name)|psi-mi:IKZF3(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554956|imex:IM-24995-4310	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003374|refseq:NP_011658.3|dip:DIP-5534N|mint:P53286|ensemblfungi:YGR142W(gene)|ensemblfungi:YGR142W_mRNA(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005634"(nucleus)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006865"(amino acid transport)|go:"GO:0006885"(regulation of pH)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051087"(chaperone binding)|go:"GO:0140311"(protein sequestering activity)	refseq:NP_001271443.1|refseq:NP_001271444.1|refseq:NP_036613.2|refseq:NP_899051.1|refseq:NP_899052.1|refseq:NP_899053.1|refseq:NP_899054.1|refseq:NP_899055.1|refseq:NP_001271445.1|refseq:NP_001244337.1|refseq:NP_001244338.1|refseq:NP_001244339.1|refseq:NP_001244340.1|refseq:NP_001244341.1|refseq:NP_001244342.1|refseq:NP_001244343.1|ensembl:ENSG00000161405(gene)|ensembl:ENST00000346872(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007498"(mesoderm development)|go:"GO:0009617"(response to bacterium)|go:"GO:0030888"(regulation of B cell proliferation)|go:"GO:0042113"(B cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045577"(regulation of B cell differentiation)|go:"GO:0045619"(regulation of lymphocyte differentiation)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|go:"GO:0046872"(metal ion binding)|dip:DIP-56975N	-	crc64:E7AE1EB1E3612F3E	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Cu27xkwGMNyS4zLvUaG1UeH2mE0559292	rogid:2Kp6LefSLfK5VIiE6DmQusFIfMY9606	intact-crc:50F41C67BF33B40E|rigid:M2ObKjk04l5z10jOQwXnunL8BtE	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q06411	uniprotkb:Q9UKT9	intact:EBI-576|uniprotkb:D6VZ60|ensemblfungi:YLR424W	intact:EBI-747204|uniprotkb:Q8WWQ9|uniprotkb:Q8WWR0|uniprotkb:Q8WWR1|uniprotkb:Q8WWR2|uniprotkb:Q8WWR3|uniprotkb:Q8N574|uniprotkb:B4DVV5|uniprotkb:Q69BL6|uniprotkb:Q69BL7|uniprotkb:Q69BL8|uniprotkb:Q69BL9|uniprotkb:Q69BM0|uniprotkb:Q69BM1|uniprotkb:Q69BM2|uniprotkb:Q69BM3|uniprotkb:Q69BM5|ensembl:ENSP00000344544	psi-mi:sp382_yeast(display_long)|uniprotkb:NTR1(gene name synonym)|uniprotkb:YLR424W(locus name)|uniprotkb:SPP382(gene name)|psi-mi:SPP382(display_short)|uniprotkb:CCF8(gene name synonym)|uniprotkb:Suppressor of PRP38 protein 2(gene name synonym)|uniprotkb:Nineteen complex-related protein 1(gene name synonym)|uniprotkb:CLF1 complex factor 8(gene name synonym)	psi-mi:ikzf3_human(display_long)|uniprotkb:ZNFN1A3(gene name synonym)|uniprotkb:Ikaros family zinc finger protein 3(gene name synonym)|uniprotkb:IKZF3(gene name)|psi-mi:IKZF3(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554964|imex:IM-24995-4312	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013528.1|sgd:S000004416|dip:DIP-1491N|mint:Q06411|ensemblfungi:YLR424W(gene)|ensemblfungi:YLR424W_mRNA(transcript)|go:"GO:0000349"(generation of catalytic spliceosome for first transesterification step)|go:"GO:0000390"(spliceosomal complex disassembly)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0071008"(U2-type post-mRNA release spliceosomal complex)|go:"GO:1904876"(negative regulation of DNA ligase activity)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR000467(D111/G-patch)|rcsb pdb:5Y88	refseq:NP_001271443.1|refseq:NP_001271444.1|refseq:NP_036613.2|refseq:NP_899051.1|refseq:NP_899052.1|refseq:NP_899053.1|refseq:NP_899054.1|refseq:NP_899055.1|refseq:NP_001271445.1|refseq:NP_001244337.1|refseq:NP_001244338.1|refseq:NP_001244339.1|refseq:NP_001244340.1|refseq:NP_001244341.1|refseq:NP_001244342.1|refseq:NP_001244343.1|ensembl:ENSG00000161405(gene)|ensembl:ENST00000346872(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007498"(mesoderm development)|go:"GO:0009617"(response to bacterium)|go:"GO:0030888"(regulation of B cell proliferation)|go:"GO:0042113"(B cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045577"(regulation of B cell differentiation)|go:"GO:0045619"(regulation of lymphocyte differentiation)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|go:"GO:0046872"(metal ion binding)|dip:DIP-56975N	-	crc64:9986B547B9582338	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:HrG54vTE2zs7jxPSzi+9eeA23/k559292	rogid:2Kp6LefSLfK5VIiE6DmQusFIfMY9606	intact-crc:53A3EFECF0DA6A13|rigid:7PHYXTkfUcGLLjnZ7vE+v4asd6U	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P46678	uniprotkb:Q9UL45	intact:EBI-19164|uniprotkb:D6W1E0|ensemblfungi:YNL039W	intact:EBI-465781|ensembl:ENSP00000220531	psi-mi:tfc5_yeast(display_long)|uniprotkb:TFIIIB90(gene name synonym)|uniprotkb:BDP1(gene name)|psi-mi:BDP1(display_short)|uniprotkb:TFC5(gene name synonym)|uniprotkb:YNL039W(locus name)|uniprotkb:N2682(orf name)	psi-mi:bl1s6_human(display_long)|uniprotkb:BLOC1S6(gene name)|psi-mi:BLOC1S6(display_short)|uniprotkb:PA(gene name synonym)|uniprotkb:PLDN(gene name synonym)|uniprotkb:Pallid protein homolog(gene name synonym)|uniprotkb:Pallidin(gene name synonym)|uniprotkb:Syntaxin 13-interacting protein(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554992|imex:IM-24995-4319	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000004984|ensemblfungi:YNL039W(gene)|ensemblfungi:YNL039W_mRNA(transcript)|go:"GO:0000126"(transcription factor TFIIIB complex)|go:"GO:0000995"(RNA polymerase III general transcription initiation factor activity)|go:"GO:0001112"(DNA-templated transcription open complex formation)|go:"GO:0001156"(TFIIIC-class transcription factor complex binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0070896"(positive regulation of transposon integration)|go:"GO:0070898"(RNA polymerase III preinitiation complex assembly)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017174(Transcription factor IIIB, Bdp1 subunit, fungi)|interpro:IPR039467|rcsb pdb:6CNB|rcsb pdb:6CNC|rcsb pdb:6CND|rcsb pdb:6CNF|rcsb pdb:6EU0|rcsb pdb:6F40|rcsb pdb:6F41|rcsb pdb:6F42|rcsb pdb:6F44|reactome:R-SCE-76061|reactome:R-SCE-76066|refseq:NP_014359.3|dip:DIP-964N|mint:P46678	ensembl:ENSG00000104164(gene)|ensembl:ENST00000220531(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0007596"(blood coagulation)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0016081"(synaptic vesicle docking)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030133"(transport vesicle)|go:"GO:0030318"(melanocyte differentiation)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0032402"(melanosome transport)|go:"GO:0032438"(melanosome organization)|go:"GO:0032816"(positive regulation of natural killer cell activation)|go:"GO:0033299"(secretion of lysosomal enzymes)|go:"GO:0035646"(endosome to melanosome transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046907"(intracellular transport)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0050942"(positive regulation of pigment cell differentiation)|go:"GO:0051015"(actin filament binding)|go:"GO:0061025"(membrane fusion)|go:"GO:0098793"(presynapse)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR017242(BLOC-1 complex, pallidin subunit)|go:"GO:0031175"(neuron projection development)|interpro:IPR028119|mint:Q9UL45|reactome:R-HSA-432722|refseq:NP_036520.1	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:UHI3UvDK3qlouZn4JrhYcxOhr1s559292	rogid:s5/ikwpqtA8Mm8gMd6ttfmBBKSA9606	intact-crc:6952851F8C0C7AA9|rigid:DTzuh9oFssqrZFkUaM1psx1rxzQ	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9UKT9	uniprotkb:P38263	intact:EBI-747204|uniprotkb:Q8WWQ9|uniprotkb:Q8WWR0|uniprotkb:Q8WWR1|uniprotkb:Q8WWR2|uniprotkb:Q8WWR3|uniprotkb:Q8N574|uniprotkb:B4DVV5|uniprotkb:Q69BL6|uniprotkb:Q69BL7|uniprotkb:Q69BL8|uniprotkb:Q69BL9|uniprotkb:Q69BM0|uniprotkb:Q69BM1|uniprotkb:Q69BM2|uniprotkb:Q69BM3|uniprotkb:Q69BM5|ensembl:ENSP00000344544	intact:EBI-20304|uniprotkb:D6VQA4|ensemblfungi:YBR105C	psi-mi:ikzf3_human(display_long)|uniprotkb:ZNFN1A3(gene name synonym)|uniprotkb:Ikaros family zinc finger protein 3(gene name synonym)|uniprotkb:IKZF3(gene name)|psi-mi:IKZF3(display_short)	psi-mi:gid4_yeast(display_long)|uniprotkb:VID24(gene name)|psi-mi:VID24(display_short)|uniprotkb:YBR105C(locus name)|uniprotkb:YBR0834(orf name)|uniprotkb:GID4(gene name synonym)|uniprotkb:Glucose-induced degradation protein 4(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554988|imex:IM-24995-4318	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001271443.1|refseq:NP_001271444.1|refseq:NP_036613.2|refseq:NP_899051.1|refseq:NP_899052.1|refseq:NP_899053.1|refseq:NP_899054.1|refseq:NP_899055.1|refseq:NP_001271445.1|refseq:NP_001244337.1|refseq:NP_001244338.1|refseq:NP_001244339.1|refseq:NP_001244340.1|refseq:NP_001244341.1|refseq:NP_001244342.1|refseq:NP_001244343.1|ensembl:ENSG00000161405(gene)|ensembl:ENST00000346872(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007498"(mesoderm development)|go:"GO:0009617"(response to bacterium)|go:"GO:0030888"(regulation of B cell proliferation)|go:"GO:0042113"(B cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045577"(regulation of B cell differentiation)|go:"GO:0045619"(regulation of lymphocyte differentiation)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|go:"GO:0046872"(metal ion binding)|dip:DIP-56975N	refseq:NP_009663.1|sgd:S000000309|ensemblfungi:YBR105C(gene)|ensemblfungi:YBR105C_mRNA(transcript)|go:"GO:0005773"(vacuole)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0007039"(protein catabolic process in the vacuole)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034657"(GID complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045721"(negative regulation of gluconeogenesis)|go:"GO:0071596"(ubiquitin-dependent protein catabolic process via the N-end rule pathway)|interpro:IPR018618|rcsb pdb:6SWY|dip:DIP-4502N|mint:P38263	-	-	crc64:FF020B239676E0B2	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:2Kp6LefSLfK5VIiE6DmQusFIfMY9606	rogid:ag6caXMIP/qIv27yJtSEmlBoI7g559292	intact-crc:F43BF1CA4ED31E6E|rigid:cTZ1r5urqYii2IhNTMEvDSPo/oQ	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9UKT9	uniprotkb:P46948	intact:EBI-747204|uniprotkb:Q8WWQ9|uniprotkb:Q8WWR0|uniprotkb:Q8WWR1|uniprotkb:Q8WWR2|uniprotkb:Q8WWR3|uniprotkb:Q8N574|uniprotkb:B4DVV5|uniprotkb:Q69BL6|uniprotkb:Q69BL7|uniprotkb:Q69BL8|uniprotkb:Q69BL9|uniprotkb:Q69BM0|uniprotkb:Q69BM1|uniprotkb:Q69BM2|uniprotkb:Q69BM3|uniprotkb:Q69BM5|ensembl:ENSP00000344544	intact:EBI-1788|uniprotkb:D6VUX7|ensemblfungi:YGR195W	psi-mi:ikzf3_human(display_long)|uniprotkb:ZNFN1A3(gene name synonym)|uniprotkb:Ikaros family zinc finger protein 3(gene name synonym)|uniprotkb:IKZF3(gene name)|psi-mi:IKZF3(display_short)	psi-mi:rrp41_yeast(display_long)|uniprotkb:SKI6(gene name)|psi-mi:SKI6(display_short)|uniprotkb:YGR195W(locus name)|uniprotkb:G7587(orf name)|uniprotkb:ECM20(gene name synonym)|uniprotkb:Ribosomal RNA-processing protein 41(gene name synonym)|uniprotkb:Superkiller protein 6(gene name synonym)|uniprotkb:Extracellular mutant protein 20(gene name synonym)|uniprotkb:RRP41(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554976|imex:IM-24995-4315	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001271443.1|refseq:NP_001271444.1|refseq:NP_036613.2|refseq:NP_899051.1|refseq:NP_899052.1|refseq:NP_899053.1|refseq:NP_899054.1|refseq:NP_899055.1|refseq:NP_001271445.1|refseq:NP_001244337.1|refseq:NP_001244338.1|refseq:NP_001244339.1|refseq:NP_001244340.1|refseq:NP_001244341.1|refseq:NP_001244342.1|refseq:NP_001244343.1|ensembl:ENSG00000161405(gene)|ensembl:ENST00000346872(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007498"(mesoderm development)|go:"GO:0009617"(response to bacterium)|go:"GO:0030888"(regulation of B cell proliferation)|go:"GO:0042113"(B cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045577"(regulation of B cell differentiation)|go:"GO:0045619"(regulation of lymphocyte differentiation)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|go:"GO:0046872"(metal ion binding)|dip:DIP-56975N	sgd:S000003427|refseq:NP_011711.3|dip:DIP-2083N|mint:P46948|ensemblfungi:YGR195W(gene)|ensemblfungi:YGR195W_mRNA(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034473"(U1 snRNA 3'-end processing)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0034476"(U5 snRNA 3'-end processing)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071039"(nuclear polyadenylation-dependent CUT catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345|rcsb pdb:2WP8|rcsb pdb:4IFD|rcsb pdb:4OO1|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5G06|rcsb pdb:5JEA|rcsb pdb:5K36|rcsb pdb:5OKZ|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-429958|reactome:R-SCE-450385|reactome:R-SCE-450513|reactome:R-SCE-6791226	-	-	crc64:C80EFFB528A43044	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:2Kp6LefSLfK5VIiE6DmQusFIfMY9606	rogid:I7vEo0EUB1jZO+3v12H0LwVbgmo559292	intact-crc:6D941F9BC948FED0|rigid:qKDGoE2ZgJtQkWAc5Ljsw98xx9w	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9UKT9	uniprotkb:P39729	intact:EBI-747204|uniprotkb:Q8WWQ9|uniprotkb:Q8WWR0|uniprotkb:Q8WWR1|uniprotkb:Q8WWR2|uniprotkb:Q8WWR3|uniprotkb:Q8N574|uniprotkb:B4DVV5|uniprotkb:Q69BL6|uniprotkb:Q69BL7|uniprotkb:Q69BL8|uniprotkb:Q69BL9|uniprotkb:Q69BM0|uniprotkb:Q69BM1|uniprotkb:Q69BM2|uniprotkb:Q69BM3|uniprotkb:Q69BM5|ensembl:ENSP00000344544	intact:EBI-20651|uniprotkb:D6VPI1|ensemblfungi:YAL036C	psi-mi:ikzf3_human(display_long)|uniprotkb:ZNFN1A3(gene name synonym)|uniprotkb:Ikaros family zinc finger protein 3(gene name synonym)|uniprotkb:IKZF3(gene name)|psi-mi:IKZF3(display_short)	psi-mi:rbg1_yeast(display_long)|uniprotkb:GTP-binding protein RBG1(gene name synonym)|uniprotkb:YAL036C(locus name)|uniprotkb:RBG1(gene name)|psi-mi:RBG1(display_short)|uniprotkb:FUN11(gene name synonym)|uniprotkb:Genetically interacts with ribosomal genes protein 1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554980|imex:IM-24995-4316	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001271443.1|refseq:NP_001271444.1|refseq:NP_036613.2|refseq:NP_899051.1|refseq:NP_899052.1|refseq:NP_899053.1|refseq:NP_899054.1|refseq:NP_899055.1|refseq:NP_001271445.1|refseq:NP_001244337.1|refseq:NP_001244338.1|refseq:NP_001244339.1|refseq:NP_001244340.1|refseq:NP_001244341.1|refseq:NP_001244342.1|refseq:NP_001244343.1|ensembl:ENSG00000161405(gene)|ensembl:ENST00000346872(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007498"(mesoderm development)|go:"GO:0009617"(response to bacterium)|go:"GO:0030888"(regulation of B cell proliferation)|go:"GO:0042113"(B cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045577"(regulation of B cell differentiation)|go:"GO:0045619"(regulation of lymphocyte differentiation)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|go:"GO:0046872"(metal ion binding)|dip:DIP-56975N	refseq:NP_009364.1|sgd:S000000034|ensemblfungi:YAL036C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005844"(polysome)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:1903833"(positive regulation of cellular response to amino acid starvation)|interpro:IPR004095(TGS)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006073(GTP1/OBG)|interpro:IPR006074(GTP1/OBG, conserved site)|interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|interpro:IPR012676(TGS-like)|interpro:IPR027417|interpro:IPR031167|interpro:IPR031662|rcsb pdb:4A9A|ensemblfungi:YAL036C(gene)|dip:DIP-1750N|mint:P39729	-	-	crc64:D25C6C732B462A6B	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:2Kp6LefSLfK5VIiE6DmQusFIfMY9606	rogid:PYUgCeuX5pWutVTDI01InMby/OE559292	intact-crc:0F5E4133981A491A|rigid:Sa2J/1L1/w2ba1KoabuxlTAyzQE	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P28004	uniprotkb:Q9UKT9	intact:EBI-20640|uniprotkb:D6VPI6|ensemblfungi:YAL032C	intact:EBI-747204|uniprotkb:Q8WWQ9|uniprotkb:Q8WWR0|uniprotkb:Q8WWR1|uniprotkb:Q8WWR2|uniprotkb:Q8WWR3|uniprotkb:Q8N574|uniprotkb:B4DVV5|uniprotkb:Q69BL6|uniprotkb:Q69BL7|uniprotkb:Q69BL8|uniprotkb:Q69BL9|uniprotkb:Q69BM0|uniprotkb:Q69BM1|uniprotkb:Q69BM2|uniprotkb:Q69BM3|uniprotkb:Q69BM5|ensembl:ENSP00000344544	psi-mi:prp45_yeast(display_long)|uniprotkb:YAL032C(locus name)|uniprotkb:PRP45(gene name)|psi-mi:PRP45(display_short)|uniprotkb:FUN20(gene name synonym)	psi-mi:ikzf3_human(display_long)|uniprotkb:ZNFN1A3(gene name synonym)|uniprotkb:Ikaros family zinc finger protein 3(gene name synonym)|uniprotkb:IKZF3(gene name)|psi-mi:IKZF3(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554984|imex:IM-24995-4317	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009370.1|sgd:S000000030|ensemblfungi:YAL032C(gene)|ensemblfungi:YAL032C_mRNA(transcript)|go:"GO:0000350"(generation of catalytic spliceosome for second transesterification step)|go:"GO:0005634"(nucleus)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|interpro:IPR004015(SKIP/SNW)|interpro:IPR017862|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|dip:DIP-2774N|mint:P28004	refseq:NP_001271443.1|refseq:NP_001271444.1|refseq:NP_036613.2|refseq:NP_899051.1|refseq:NP_899052.1|refseq:NP_899053.1|refseq:NP_899054.1|refseq:NP_899055.1|refseq:NP_001271445.1|refseq:NP_001244337.1|refseq:NP_001244338.1|refseq:NP_001244339.1|refseq:NP_001244340.1|refseq:NP_001244341.1|refseq:NP_001244342.1|refseq:NP_001244343.1|ensembl:ENSG00000161405(gene)|ensembl:ENST00000346872(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007498"(mesoderm development)|go:"GO:0009617"(response to bacterium)|go:"GO:0030888"(regulation of B cell proliferation)|go:"GO:0042113"(B cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045577"(regulation of B cell differentiation)|go:"GO:0045619"(regulation of lymphocyte differentiation)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|go:"GO:0046872"(metal ion binding)|dip:DIP-56975N	-	crc64:FE5A724186D7FE84	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:qoHF1UsO3k+JOTOfigSuy2P84/k559292	rogid:2Kp6LefSLfK5VIiE6DmQusFIfMY9606	intact-crc:9C8EE0D3328F3B9E|rigid:v6leynU3zaB55LIQL3Ag/PFxtks	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P40092	uniprotkb:Q9UMX0	intact:EBI-22721|uniprotkb:D3DM57|ensemblfungi:YER150W	intact:EBI-741480|uniprotkb:Q8IXS9|uniprotkb:Q8N2Q3|uniprotkb:Q9H0T8|uniprotkb:Q9H3R4|uniprotkb:Q9HAZ5|intact:EBI-28967608|ensembl:ENSP00000365576|uniprotkb:Q5T6J5|uniprotkb:Q5T6J9|uniprotkb:A0A024R284	psi-mi:spi1_yeast(display_long)|uniprotkb:YER150W(locus name)|uniprotkb:SPI1(gene name)|psi-mi:SPI1(display_short)|uniprotkb:Stationary phase-induced protein 1(gene name synonym)	psi-mi:ubql1_human(display_long)|uniprotkb:Protein linking IAP with cytoskeleton 1(gene name synonym)|uniprotkb:UBQLN1(gene name)|psi-mi:UBQLN1(display_short)|uniprotkb:DA41(gene name synonym)|uniprotkb:PLIC1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11555012|imex:IM-24995-4324	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000000952|refseq:NP_011077.1|dip:DIP-2064N|go:"GO:0071944"(cell periphery)|interpro:IPR038843|go:"GO:0031505"(fungal-type cell wall organization)|ensemblfungi:YER150W(gene)|ensemblfungi:YER150W_mRNA(transcript)|go:"GO:0005199"(structural constituent of cell wall)|go:"GO:0005576"(extracellular region)|go:"GO:0009277"(fungal-type cell wall)|go:"GO:0010447"(response to acidic pH)|go:"GO:0031225"(anchored component of membrane)	ensembl:ENST00000257468|ensembl:ENSP00000257468|ensembl:ENSP00000365576|ensembl:ENSG00000135018(gene)|ensembl:ENST00000376395(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000502"(proteasome complex)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016235"(aggresome)|go:"GO:0016236"(macroautophagy)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0019900"(kinase binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035973"(aggrephagy)|go:"GO:0042802"(identical protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0097352"(autophagosome maturation)|go:"GO:1901340"(negative regulation of store-operated calcium channel activity)|go:"GO:1902175"(regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)|interpro:IPR000626(Ubiquitin)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR028430|interpro:IPR029071|mint:Q9UMX0|rcsb pdb:2JY5|rcsb pdb:2JY6|rcsb pdb:2KLC|reactome:R-HSA-8856825|refseq:NP_038466.2|refseq:NP_444295.1|dip:DIP-41629N	-	crc64:F65B20225FE2A5ED	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:0S1OQwJ9EXGKjALQ4oF2uW7KCjc559292	rogid:nCFfZbGCTvRYaXhQ4R99XblslvM9606	intact-crc:56A6BD1D6B5AAF8D|rigid:01eOMBD/vl6nTSTP4Kt9aXWkDe0	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P38886	uniprotkb:Q9UMX0	intact:EBI-15949|ensemblfungi:YHR200W|uniprotkb:D3DLE9	intact:EBI-741480|uniprotkb:Q8IXS9|uniprotkb:Q8N2Q3|uniprotkb:Q9H0T8|uniprotkb:Q9H3R4|uniprotkb:Q9HAZ5|intact:EBI-28967608|ensembl:ENSP00000365576|uniprotkb:Q5T6J5|uniprotkb:Q5T6J9|uniprotkb:A0A024R284	psi-mi:rpn10_yeast(display_long)|uniprotkb:RPN10(gene name)|psi-mi:RPN10(display_short)|uniprotkb:MCB1(gene name synonym)|uniprotkb:SUN1(gene name synonym)|uniprotkb:YHR200W(locus name)	psi-mi:ubql1_human(display_long)|uniprotkb:Protein linking IAP with cytoskeleton 1(gene name synonym)|uniprotkb:UBQLN1(gene name)|psi-mi:UBQLN1(display_short)|uniprotkb:DA41(gene name synonym)|uniprotkb:PLIC1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11555008|imex:IM-24995-4323	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YHR200W(gene)|ensemblfungi:YHR200W_mRNA(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|sgd:S000001243|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0036435"(K48-linked polyubiquitin modification-dependent protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043248"(proteasome assembly)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR027040|interpro:IPR036465|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5LN1|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5MPD|rcsb pdb:5MPE|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|refseq:NP_012070.3|dip:DIP-2100N|mint:P38886	ensembl:ENST00000257468|ensembl:ENSP00000257468|ensembl:ENSP00000365576|ensembl:ENSG00000135018(gene)|ensembl:ENST00000376395(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000502"(proteasome complex)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016235"(aggresome)|go:"GO:0016236"(macroautophagy)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0019900"(kinase binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035973"(aggrephagy)|go:"GO:0042802"(identical protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0097352"(autophagosome maturation)|go:"GO:1901340"(negative regulation of store-operated calcium channel activity)|go:"GO:1902175"(regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)|interpro:IPR000626(Ubiquitin)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR028430|interpro:IPR029071|mint:Q9UMX0|rcsb pdb:2JY5|rcsb pdb:2JY6|rcsb pdb:2KLC|reactome:R-HSA-8856825|refseq:NP_038466.2|refseq:NP_444295.1|dip:DIP-41629N	-	crc64:8A05198B0CD7C0C3	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:Lg2bjPWMUcvXdLDZZMWFWyXbCcA559292	rogid:nCFfZbGCTvRYaXhQ4R99XblslvM9606	intact-crc:6232C1FDDE847A8C|rigid:jRQ6SH8wVZdoEyLJO0cGcrIO2eI	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P38340	uniprotkb:Q9ULA0	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-748356|uniprotkb:Q9BW44|uniprotkb:Q9NUV5|uniprotkb:Q9NV55|ensembl:ENSP00000273075	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:dnpep_human(display_long)|uniprotkb:ASPEP(gene name synonym)|uniprotkb:DAP(gene name synonym)|uniprotkb:DNPEP(gene name)|psi-mi:DNPEP(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11554996|imex:IM-24995-4320	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F	refseq:NP_001306049.1|refseq:NP_036232.2|ensembl:ENSG00000123992(gene)|ensembl:ENST00000273075(transcript)|go:"GO:0004177"(aminopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006518"(peptide metabolic process)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0072562"(blood microparticle)|interpro:IPR001948(Peptidase M18, aminopeptidase I)|interpro:IPR023358|rcsb pdb:4DYO	-	crc64:66699F37B0013088	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2020/10/21	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:xG06vZosglPmA5ktZd8A8EH9h0g9606	intact-crc:BC39BDFF4CE82059|rigid:Fp77wJo8+HbRZpyPHuZBtGTjUXA	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P15202	uniprotkb:Q9ULX6	intact:EBI-4061|uniprotkb:E9P947|uniprotkb:D6VSN6|ensemblfungi:YDR256C	intact:EBI-357530|uniprotkb:O94792|uniprotkb:Q96J58|uniprotkb:Q9NRQ0|uniprotkb:Q9UGM0|uniprotkb:B5BU90|uniprotkb:B4DJ74|ensembl:ENSP00000380557	psi-mi:cata_yeast(display_long)|uniprotkb:YD9320A.06C(orf name)|uniprotkb:YDR256C(locus name)|uniprotkb:CTA1(gene name)|psi-mi:CTA1(display_short)	psi-mi:akp8l_human(display_long)|uniprotkb:AKAP8L(gene name)|psi-mi:AKAP8L(display_short)|uniprotkb:HRIHFB2018(orf name)|uniprotkb:NAKAP95(gene name synonym)|uniprotkb:Neighbor of A-kinase-anchoring protein 95(gene name synonym)|uniprotkb:Homologous to AKAP95 protein(gene name synonym)|uniprotkb:Helicase A-binding protein 95(gene name synonym)|uniprotkb:NAKAP(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11555000|imex:IM-24995-4321	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002664|refseq:NP_010542.1|dip:DIP-4320N|mint:P15202|ensemblfungi:YDR256C(gene)|ensemblfungi:YDR256C_mRNA(transcript)|go:"GO:0000302"(response to reactive oxygen species)|go:"GO:0001315"(age-dependent response to reactive oxygen species)|go:"GO:0004096"(catalase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005777"(peroxisome)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0020037"(heme binding)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0046872"(metal ion binding)|interpro:IPR002226(Catalase)|interpro:IPR010582(Catalase-related)|interpro:IPR011614(Catalase, N-terminal)|interpro:IPR018028|interpro:IPR020835|interpro:IPR024708|interpro:IPR024711|rcsb pdb:1A4E	refseq:NP_001278407.1|refseq:NP_055186.3|dip:DIP-27541N|ensembl:ENSG00000011243(gene)|ensembl:ENST00000397410(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010793"(regulation of mRNA export from nucleus)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016605"(PML body)|go:"GO:0016607"(nuclear speck)|go:"GO:0017151"(DEAD/H-box RNA helicase binding)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0033127"(regulation of histone phosphorylation)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0044839"(cell cycle G2/M phase transition)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0051081"(nuclear membrane disassembly)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR007071("A-kinase anchoring protein 95 (AKAP95)")|interpro:IPR034736|mint:Q9ULX6	-	crc64:22DFCC599D79801F	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2018/09/18	rogid:+NMosmB3jzYGleF7X88sJ2qLm/Y559292	rogid:SAs8jxuWxLOiWN/TRyjVvr5m/5Y9606	intact-crc:62067FF06D4588D8|rigid:MQs7mJ+EXKvoppESJeluyw51LxA	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q04201	uniprotkb:Q9UMX0	intact:EBI-27928|uniprotkb:D6W0I3|ensemblfungi:YML101C	intact:EBI-741480|uniprotkb:Q8IXS9|uniprotkb:Q8N2Q3|uniprotkb:Q9H0T8|uniprotkb:Q9H3R4|uniprotkb:Q9HAZ5|intact:EBI-28967608|ensembl:ENSP00000365576|uniprotkb:Q5T6J5|uniprotkb:Q5T6J9|uniprotkb:A0A024R284	psi-mi:cue4_yeast(display_long)|uniprotkb:YML101C(locus name)|uniprotkb:Coupling of ubiquitin conjugation to ER degradation protein 4(gene name synonym)|uniprotkb:CUE4(gene name)|psi-mi:CUE4(display_short)	psi-mi:ubql1_human(display_long)|uniprotkb:Protein linking IAP with cytoskeleton 1(gene name synonym)|uniprotkb:UBQLN1(gene name)|psi-mi:UBQLN1(display_short)|uniprotkb:DA41(gene name synonym)|uniprotkb:PLIC1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11555004|imex:IM-24995-4322	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013607.1|sgd:S000004568|dip:DIP-4525N|mint:Q04201|ensemblfungi:YML101C(gene)|ensemblfungi:YML101C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR003892(Ubiquitin system component Cue)	ensembl:ENST00000257468|ensembl:ENSP00000257468|ensembl:ENSP00000365576|ensembl:ENSG00000135018(gene)|ensembl:ENST00000376395(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000502"(proteasome complex)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016235"(aggresome)|go:"GO:0016236"(macroautophagy)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0019900"(kinase binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035973"(aggrephagy)|go:"GO:0042802"(identical protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0097352"(autophagosome maturation)|go:"GO:1901340"(negative regulation of store-operated calcium channel activity)|go:"GO:1902175"(regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)|interpro:IPR000626(Ubiquitin)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR028430|interpro:IPR029071|mint:Q9UMX0|rcsb pdb:2JY5|rcsb pdb:2JY6|rcsb pdb:2KLC|reactome:R-HSA-8856825|refseq:NP_038466.2|refseq:NP_444295.1|dip:DIP-41629N	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:NMBJHZbX4/gU01fk4evPDXm/M6w559292	rogid:nCFfZbGCTvRYaXhQ4R99XblslvM9606	intact-crc:133682E4FABD7A20|rigid:ZKinB3+wtv/LmQxyK10PpKsDcag	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P00431	uniprotkb:Q9UMX0	intact:EBI-4389|uniprotkb:Q6Q5M9|uniprotkb:D6VXC7|ensemblfungi:YKR066C	intact:EBI-741480|uniprotkb:Q8IXS9|uniprotkb:Q8N2Q3|uniprotkb:Q9H0T8|uniprotkb:Q9H3R4|uniprotkb:Q9HAZ5|intact:EBI-28967608|ensembl:ENSP00000365576|uniprotkb:Q5T6J5|uniprotkb:Q5T6J9|uniprotkb:A0A024R284	psi-mi:ccpr_yeast(display_long)|uniprotkb:CCP1(gene name)|psi-mi:CCP1(display_short)|uniprotkb:CCP(gene name synonym)|uniprotkb:CPO(gene name synonym)|uniprotkb:YKR066C(locus name)	psi-mi:ubql1_human(display_long)|uniprotkb:Protein linking IAP with cytoskeleton 1(gene name synonym)|uniprotkb:UBQLN1(gene name)|psi-mi:UBQLN1(display_short)|uniprotkb:DA41(gene name synonym)|uniprotkb:PLIC1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11555028|imex:IM-24995-4328	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012992.1|sgd:S000001774|dip:DIP-6251N|ensemblfungi:YKR066C(gene)|ensemblfungi:YKR066C_mRNA(transcript)|go:"GO:0000302"(response to reactive oxygen species)|go:"GO:0004130"(cytochrome-c peroxidase activity)|go:"GO:0004601"(peroxidase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0020037"(heme binding)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0046872"(metal ion binding)|interpro:IPR002016(Haem peroxidase, plant/fungal/bacterial)|interpro:IPR002207(Plant ascorbate peroxidase)|interpro:IPR010255(Haem peroxidase)|interpro:IPR019793|interpro:IPR019794|interpro:IPR044831|rcsb pdb:1A2F|rcsb pdb:1A2G|rcsb pdb:1AA4|rcsb pdb:1AC4|rcsb pdb:1AC8|rcsb pdb:1AEB|rcsb pdb:1AED|rcsb pdb:1AEE|rcsb pdb:1AEF|rcsb pdb:1AEG|rcsb pdb:1AEH|rcsb pdb:1AEJ|rcsb pdb:1AEK|rcsb pdb:1AEM|rcsb pdb:1AEN|rcsb pdb:1AEO|rcsb pdb:1AEQ|rcsb pdb:1AES|rcsb pdb:1AET|rcsb pdb:1AEU|rcsb pdb:1AEV|rcsb pdb:1BEJ|rcsb pdb:1BEK|rcsb pdb:1BEM|rcsb pdb:1BEP|rcsb pdb:1BEQ|rcsb pdb:1BES|rcsb pdb:1BJ9|rcsb pdb:1BVA|rcsb pdb:1CCA|rcsb pdb:1CCB|rcsb pdb:1CCC|rcsb pdb:1CCE|rcsb pdb:1CCG|rcsb pdb:1CCI|rcsb pdb:1CCJ|rcsb pdb:1CCK|rcsb pdb:1CCL|rcsb pdb:1CCP|rcsb pdb:1CMP|rcsb pdb:1CMQ|rcsb pdb:1CMT|rcsb pdb:1CPD|rcsb pdb:1CPE|rcsb pdb:1CPF|rcsb pdb:1CPG|rcsb pdb:1CYF|rcsb pdb:1DCC|rcsb pdb:1DJ1|rcsb pdb:1DJ5|rcsb pdb:1DS4|rcsb pdb:1DSE|rcsb pdb:1DSG|rcsb pdb:1DSO|rcsb pdb:1DSP|rcsb pdb:1EBE|rcsb pdb:1JCI|rcsb pdb:1JDR|rcsb pdb:1KOK|rcsb pdb:1KRJ|rcsb pdb:1KXM|rcsb pdb:1KXN|rcsb pdb:1MK8|rcsb pdb:1MKQ|rcsb pdb:1MKR|rcsb pdb:1ML2|rcsb pdb:1RYC|rcsb pdb:1S6V|rcsb pdb:1S73|rcsb pdb:1SBM|rcsb pdb:1SDQ|rcsb pdb:1SOG|rcsb pdb:1STQ|rcsb pdb:1U74|rcsb pdb:1U75|rcsb pdb:1Z53|rcsb pdb:1ZBY|rcsb pdb:1ZBZ|rcsb pdb:2ANZ|rcsb pdb:2AQD|rcsb pdb:2AS1|rcsb pdb:2AS2|rcsb pdb:2AS3|rcsb pdb:2AS4|rcsb pdb:2AS6|rcsb pdb:2B0Z|rcsb pdb:2B10|rcsb pdb:2B11|rcsb pdb:2B12|rcsb pdb:2BCN|rcsb pdb:2CCP|rcsb pdb:2CEP|rcsb pdb:2CYP|rcsb pdb:2EUN|rcsb pdb:2EUO|rcsb pdb:2EUP|rcsb pdb:2EUQ|rcsb pdb:2EUR|rcsb pdb:2EUS|rcsb pdb:2EUT|rcsb pdb:2EUU|rcsb pdb:2GB8|rcsb pdb:2IA8|rcsb pdb:2ICV|rcsb pdb:2JTI|rcsb pdb:2N18|rcsb pdb:2PCB|rcsb pdb:2PCC|rcsb pdb:2RBT|rcsb pdb:2RBU|rcsb pdb:2RBV|rcsb pdb:2RBW|rcsb pdb:2RBX|rcsb pdb:2RBY|rcsb pdb:2RBZ|rcsb pdb:2RC0|rcsb pdb:2RC1|rcsb pdb:2RC2|rcsb pdb:2V23|rcsb pdb:2V2E|rcsb pdb:2X07|rcsb pdb:2X08|rcsb pdb:2XIL|rcsb pdb:2XJ5|rcsb pdb:2XJ8|rcsb pdb:2Y5A|rcsb pdb:2YCG|rcsb pdb:3CCP|rcsb pdb:3CCX|rcsb pdb:3E2N|rcsb pdb:3E2O|rcsb pdb:3EXB|rcsb pdb:3M23|rcsb pdb:3M25|rcsb pdb:3M26|rcsb pdb:3M27|rcsb pdb:3M28|rcsb pdb:3M29|rcsb pdb:3M2A|rcsb pdb:1CMU|rcsb pdb:3M2B|rcsb pdb:3M2C|rcsb pdb:3M2D|rcsb pdb:3M2E|rcsb pdb:3M2F|rcsb pdb:3M2G|rcsb pdb:3M2H|rcsb pdb:3M2I|rcsb pdb:3R98|rcsb pdb:3R99|rcsb pdb:4A6Z|rcsb pdb:4A71|rcsb pdb:4A78|rcsb pdb:4A7M|rcsb pdb:4CCP|rcsb pdb:4CCX|rcsb pdb:4CVI|rcsb pdb:4CVJ|rcsb pdb:4JB4|rcsb pdb:4NFG|rcsb pdb:4P4Q|rcsb pdb:4XV4|rcsb pdb:4XV5|rcsb pdb:4XV6|rcsb pdb:4XV7|rcsb pdb:4XV8|rcsb pdb:4XVA|rcsb pdb:5CCP|rcsb pdb:5CIB|rcsb pdb:5CIC|rcsb pdb:5CID|rcsb pdb:5CIE|rcsb pdb:5CIF|rcsb pdb:5CIG|rcsb pdb:5CIH|rcsb pdb:5D6M|rcsb pdb:5EJT|rcsb pdb:5EJX|rcsb pdb:6CCP|rcsb pdb:6H08|rcsb pdb:6P41|rcsb pdb:6P42|rcsb pdb:6P43|rcsb pdb:6Y1T|rcsb pdb:6Y2Y|rcsb pdb:7CCP	ensembl:ENST00000257468|ensembl:ENSP00000257468|ensembl:ENSP00000365576|ensembl:ENSG00000135018(gene)|ensembl:ENST00000376395(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000502"(proteasome complex)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016235"(aggresome)|go:"GO:0016236"(macroautophagy)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0019900"(kinase binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035973"(aggrephagy)|go:"GO:0042802"(identical protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0097352"(autophagosome maturation)|go:"GO:1901340"(negative regulation of store-operated calcium channel activity)|go:"GO:1902175"(regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)|interpro:IPR000626(Ubiquitin)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR028430|interpro:IPR029071|mint:Q9UMX0|rcsb pdb:2JY5|rcsb pdb:2JY6|rcsb pdb:2KLC|reactome:R-HSA-8856825|refseq:NP_038466.2|refseq:NP_444295.1|dip:DIP-41629N	-	crc64:A5D26385DA6F0A0B	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:LkPXY1wuYoCFzMQPSsAtXZrRi8w559292	rogid:nCFfZbGCTvRYaXhQ4R99XblslvM9606	intact-crc:5DC342579DD38897|rigid:g40l7JFLNqTJJNp+yGPGLvMZdY4	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:A0A6A5PVQ3	uniprotkb:Q9UMX0	intact:EBI-11522614	intact:EBI-741480|uniprotkb:Q8IXS9|uniprotkb:Q8N2Q3|uniprotkb:Q9H0T8|uniprotkb:Q9H3R4|uniprotkb:Q9HAZ5|intact:EBI-28967608|ensembl:ENSP00000365576|uniprotkb:Q5T6J5|uniprotkb:Q5T6J9|uniprotkb:A0A024R284	psi-mi:a0a6a5pvq3_yeasx(display_long)|uniprotkb:PACBIOSEQ_LOCUS3560(orf name)|uniprotkb:PACBIOSEQ_LOCUS3564(orf name)|uniprotkb:PACBIOSEQ_LOCUS3592(orf name)|uniprotkb:PACBIOSEQ_LOCUS3594(orf name)|uniprotkb:PACBIOSEQ_LOCUS3635(orf name)|uniprotkb:SCNYR20_0010010900(orf name)|uniprotkb:SCP684_0010010800(orf name)	psi-mi:ubql1_human(display_long)|uniprotkb:Protein linking IAP with cytoskeleton 1(gene name synonym)|uniprotkb:UBQLN1(gene name)|psi-mi:UBQLN1(display_short)|uniprotkb:DA41(gene name synonym)|uniprotkb:PLIC1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11555024|imex:IM-24995-4327	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR000420(Yeast PIR protein repeat)|go:"GO:0005199"(structural constituent of cell wall)|go:"GO:0005618"(cell wall)|uniprotkb:A0A250WIX2(uniprot-removed-ac)	ensembl:ENST00000257468|ensembl:ENSP00000257468|ensembl:ENSP00000365576|ensembl:ENSG00000135018(gene)|ensembl:ENST00000376395(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000502"(proteasome complex)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016235"(aggresome)|go:"GO:0016236"(macroautophagy)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0019900"(kinase binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035973"(aggrephagy)|go:"GO:0042802"(identical protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0097352"(autophagosome maturation)|go:"GO:1901340"(negative regulation of store-operated calcium channel activity)|go:"GO:1902175"(regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)|interpro:IPR000626(Ubiquitin)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR028430|interpro:IPR029071|mint:Q9UMX0|rcsb pdb:2JY5|rcsb pdb:2JY6|rcsb pdb:2KLC|reactome:R-HSA-8856825|refseq:NP_038466.2|refseq:NP_444295.1|dip:DIP-41629N	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:I1pf6N/8dUODvb5jhcXC902uuew4932	rogid:nCFfZbGCTvRYaXhQ4R99XblslvM9606	intact-crc:E408171E1F316128|rigid:+8QzAI8pX+olAfWRefZI12z170I	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P54860	uniprotkb:Q9UMX0	intact:EBI-20003|uniprotkb:D6VRG3|ensemblfungi:YDL190C	intact:EBI-741480|uniprotkb:Q8IXS9|uniprotkb:Q8N2Q3|uniprotkb:Q9H0T8|uniprotkb:Q9H3R4|uniprotkb:Q9HAZ5|intact:EBI-28967608|ensembl:ENSP00000365576|uniprotkb:Q5T6J5|uniprotkb:Q5T6J9|uniprotkb:A0A024R284	psi-mi:ufd2_yeast(display_long)|uniprotkb:UFD2(gene name)|psi-mi:UFD2(display_short)|uniprotkb:YDL190C(locus name)|uniprotkb:D1255(orf name)|uniprotkb:Ubiquitin fusion degradation protein 2(gene name synonym)|uniprotkb:Ubiquitin conjugation factor E4(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase UFD2(gene name synonym)	psi-mi:ubql1_human(display_long)|uniprotkb:Protein linking IAP with cytoskeleton 1(gene name synonym)|uniprotkb:UBQLN1(gene name)|psi-mi:UBQLN1(display_short)|uniprotkb:DA41(gene name synonym)|uniprotkb:PLIC1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11555032|imex:IM-24995-4329	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010091.2|sgd:S000002349|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR003613(U box)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|go:"GO:0016567"(protein ubiquitination)|interpro:IPR019474|rcsb pdb:2QIZ|rcsb pdb:2QJ0|rcsb pdb:3M62|rcsb pdb:3M63|reactome:R-SCE-983168|ensemblfungi:YDL190C(gene)|ensemblfungi:YDL190C_mRNA(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|dip:DIP-5925N|mint:P54860	ensembl:ENST00000257468|ensembl:ENSP00000257468|ensembl:ENSP00000365576|ensembl:ENSG00000135018(gene)|ensembl:ENST00000376395(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000502"(proteasome complex)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016235"(aggresome)|go:"GO:0016236"(macroautophagy)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0019900"(kinase binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035973"(aggrephagy)|go:"GO:0042802"(identical protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0097352"(autophagosome maturation)|go:"GO:1901340"(negative regulation of store-operated calcium channel activity)|go:"GO:1902175"(regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)|interpro:IPR000626(Ubiquitin)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR028430|interpro:IPR029071|mint:Q9UMX0|rcsb pdb:2JY5|rcsb pdb:2JY6|rcsb pdb:2KLC|reactome:R-HSA-8856825|refseq:NP_038466.2|refseq:NP_444295.1|dip:DIP-41629N	-	crc64:877ACB59AC29634A	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:E8YkPPAM7RTsLwjUHSHNCjQWq9M559292	rogid:nCFfZbGCTvRYaXhQ4R99XblslvM9606	intact-crc:4E600367AF5D4742|rigid:4IfUBzrlDlTBoaaa1l8LS7SojVE	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P38868	uniprotkb:Q9UMX0	intact:EBI-24840|uniprotkb:A0A1S0T004|ensemblfungi:YHR180W	intact:EBI-741480|uniprotkb:Q8IXS9|uniprotkb:Q8N2Q3|uniprotkb:Q9H0T8|uniprotkb:Q9H3R4|uniprotkb:Q9HAZ5|intact:EBI-28967608|ensembl:ENSP00000365576|uniprotkb:Q5T6J5|uniprotkb:Q5T6J9|uniprotkb:A0A024R284	psi-mi:yhy0_yeast(display_long)|uniprotkb:YHR180W(locus name)	psi-mi:ubql1_human(display_long)|uniprotkb:Protein linking IAP with cytoskeleton 1(gene name synonym)|uniprotkb:UBQLN1(gene name)|psi-mi:UBQLN1(display_short)|uniprotkb:DA41(gene name synonym)|uniprotkb:PLIC1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11555016|imex:IM-24995-4325	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000001223|dip:DIP-4332N|ensemblfungi:YHR180W(gene)|ensemblfungi:YHR180W_mRNA(transcript)|go:"GO:0016021"(integral component of membrane)	ensembl:ENST00000257468|ensembl:ENSP00000257468|ensembl:ENSP00000365576|ensembl:ENSG00000135018(gene)|ensembl:ENST00000376395(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000502"(proteasome complex)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016235"(aggresome)|go:"GO:0016236"(macroautophagy)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0019900"(kinase binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035973"(aggrephagy)|go:"GO:0042802"(identical protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0097352"(autophagosome maturation)|go:"GO:1901340"(negative regulation of store-operated calcium channel activity)|go:"GO:1902175"(regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)|interpro:IPR000626(Ubiquitin)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR028430|interpro:IPR029071|mint:Q9UMX0|rcsb pdb:2JY5|rcsb pdb:2JY6|rcsb pdb:2KLC|reactome:R-HSA-8856825|refseq:NP_038466.2|refseq:NP_444295.1|dip:DIP-41629N	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:E7zJN1iVyb08WvBGa7NXcqw4sqw559292	rogid:nCFfZbGCTvRYaXhQ4R99XblslvM9606	intact-crc:0F511F85F9841BCF|rigid:q50hN7Nm+coUXkalINXCfafkEsE	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9UMX0	intact:EBI-11522626	intact:EBI-741480|uniprotkb:Q8IXS9|uniprotkb:Q8N2Q3|uniprotkb:Q9H0T8|uniprotkb:Q9H3R4|uniprotkb:Q9HAZ5|intact:EBI-28967608|ensembl:ENSP00000365576|uniprotkb:Q5T6J5|uniprotkb:Q5T6J9|uniprotkb:A0A024R284	-	psi-mi:ubql1_human(display_long)|uniprotkb:Protein linking IAP with cytoskeleton 1(gene name synonym)|uniprotkb:UBQLN1(gene name)|psi-mi:UBQLN1(display_short)|uniprotkb:DA41(gene name synonym)|uniprotkb:PLIC1(gene name synonym)	psi-mi:a0a6a5q521_yeasx(display_short)|psi-mi:EBI-11522626(display_long)|uniprotkb:PACBIOSEQ_LOCUS284(orf name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11555020|imex:IM-24995-4326	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000257468|ensembl:ENSP00000257468|ensembl:ENSP00000365576|ensembl:ENSG00000135018(gene)|ensembl:ENST00000376395(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000502"(proteasome complex)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016235"(aggresome)|go:"GO:0016236"(macroautophagy)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0019900"(kinase binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035973"(aggrephagy)|go:"GO:0042802"(identical protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0097352"(autophagosome maturation)|go:"GO:1901340"(negative regulation of store-operated calcium channel activity)|go:"GO:1902175"(regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)|interpro:IPR000626(Ubiquitin)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR028430|interpro:IPR029071|mint:Q9UMX0|rcsb pdb:2JY5|rcsb pdb:2JY6|rcsb pdb:2KLC|reactome:R-HSA-8856825|refseq:NP_038466.2|refseq:NP_444295.1|dip:DIP-41629N	uniprotkb:A0A6A5Q521(uniprot-removed-ac)	-	-	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:nCFfZbGCTvRYaXhQ4R99XblslvM9606	rogid:FaEZGfVcEXllbT1sM1VpEOeuSZ44932	intact-crc:F8B3E8E35F1DBF7D|rigid:Tg01hQ8vVfdjzmV3F2fkNjQw2B4	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9UMX0	uniprotkb:P61829	intact:EBI-741480|uniprotkb:Q8IXS9|uniprotkb:Q8N2Q3|uniprotkb:Q9H0T8|uniprotkb:Q9H3R4|uniprotkb:Q9HAZ5|intact:EBI-28967608|ensembl:ENSP00000365576|uniprotkb:Q5T6J5|uniprotkb:Q5T6J9|uniprotkb:A0A024R284	intact:EBI-9016907|uniprotkb:P00841|uniprotkb:Q37750|uniprotkb:A0A0A7P075|ensemblfungi:Q0130	psi-mi:ubql1_human(display_long)|uniprotkb:Protein linking IAP with cytoskeleton 1(gene name synonym)|uniprotkb:UBQLN1(gene name)|psi-mi:UBQLN1(display_short)|uniprotkb:DA41(gene name synonym)|uniprotkb:PLIC1(gene name synonym)	psi-mi:atp9_yeast(display_long)|uniprotkb:OLI1(gene name)|psi-mi:OLI1(display_short)|uniprotkb:ATP9(gene name synonym)|uniprotkb:Lipid-binding protein(gene name synonym)|uniprotkb:OLI3(gene name synonym)|uniprotkb:Oligomycin resistance protein 1(gene name synonym)|uniprotkb:PHO2(gene name synonym)|uniprotkb:Q0130(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11555052|imex:IM-24995-4334	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000257468|ensembl:ENSP00000257468|ensembl:ENSP00000365576|ensembl:ENSG00000135018(gene)|ensembl:ENST00000376395(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000502"(proteasome complex)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016235"(aggresome)|go:"GO:0016236"(macroautophagy)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0019900"(kinase binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035973"(aggrephagy)|go:"GO:0042802"(identical protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0097352"(autophagosome maturation)|go:"GO:1901340"(negative regulation of store-operated calcium channel activity)|go:"GO:1902175"(regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)|interpro:IPR000626(Ubiquitin)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR028430|interpro:IPR029071|mint:Q9UMX0|rcsb pdb:2JY5|rcsb pdb:2JY6|rcsb pdb:2KLC|reactome:R-HSA-8856825|refseq:NP_038466.2|refseq:NP_444295.1|dip:DIP-41629N	reactome:R-SCE-163210|reactome:R-SCE-8949613|refseq:NP_009319.1|sgd:S000007274|refseq:YP_009144710.1|ensemblfungi:Q0130(gene)|ensemblfungi:Q0130_mRNA(transcript)|go:"GO:0000276"("mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)")|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005829"(cytosol)|go:"GO:0008289"(lipid binding)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045263"("proton-transporting ATP synthase complex, coupling factor F(o)")|interpro:IPR000454(ATPase, F0 complex, subunit C)|interpro:IPR002379(ATPase, F0/V0 complex, subunit C)|interpro:IPR020537|interpro:IPR035921|interpro:IPR038662|rcsb pdb:2WPD|rcsb pdb:2XOK|rcsb pdb:3U2F|rcsb pdb:3U2Y|rcsb pdb:3U32|rcsb pdb:3UD0|rcsb pdb:3ZRY|rcsb pdb:4B2Q|rcsb pdb:4F4S|rcsb pdb:5BPS|rcsb pdb:5BQ6|rcsb pdb:5BQA|rcsb pdb:5BQJ|rcsb pdb:6B2Z|rcsb pdb:6B8H|rcsb pdb:6CP3|rcsb pdb:6CP5|rcsb pdb:6CP6|rcsb pdb:6CP7|rcsb pdb:6WTD|dip:DIP-3041N	-	-	crc64:82B4477D6F75D758	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:nCFfZbGCTvRYaXhQ4R99XblslvM9606	rogid:z8+f6dq67i096v23FKqgqAt3Ba4559292	intact-crc:A923E679879BA9DB|rigid:jygzs/RZYkYaXr521b/0wzywZAs	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9UMX0	uniprotkb:Q02771	intact:EBI-741480|uniprotkb:Q8IXS9|uniprotkb:Q8N2Q3|uniprotkb:Q9H0T8|uniprotkb:Q9H3R4|uniprotkb:Q9HAZ5|intact:EBI-28967608|ensembl:ENSP00000365576|uniprotkb:Q5T6J5|uniprotkb:Q5T6J9|uniprotkb:A0A024R284	intact:EBI-14092|ensemblfungi:YER058W|uniprotkb:D3DLW2	psi-mi:ubql1_human(display_long)|uniprotkb:Protein linking IAP with cytoskeleton 1(gene name synonym)|uniprotkb:UBQLN1(gene name)|psi-mi:UBQLN1(display_short)|uniprotkb:DA41(gene name synonym)|uniprotkb:PLIC1(gene name synonym)	psi-mi:pt117_yeast(display_long)|uniprotkb:PET117(gene name)|psi-mi:PET117(display_short)|uniprotkb:YER058W(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11555048|imex:IM-24995-4333	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000257468|ensembl:ENSP00000257468|ensembl:ENSP00000365576|ensembl:ENSG00000135018(gene)|ensembl:ENST00000376395(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000502"(proteasome complex)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016235"(aggresome)|go:"GO:0016236"(macroautophagy)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0019900"(kinase binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035973"(aggrephagy)|go:"GO:0042802"(identical protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0097352"(autophagosome maturation)|go:"GO:1901340"(negative regulation of store-operated calcium channel activity)|go:"GO:1902175"(regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)|interpro:IPR000626(Ubiquitin)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR028430|interpro:IPR029071|mint:Q9UMX0|rcsb pdb:2JY5|rcsb pdb:2JY6|rcsb pdb:2KLC|reactome:R-HSA-8856825|refseq:NP_038466.2|refseq:NP_444295.1|dip:DIP-41629N	sgd:S000000860|refseq:NP_010979.1|ensemblfungi:YER058W(gene)|ensemblfungi:YER058W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0033617"(mitochondrial cytochrome c oxidase assembly)|go:"GO:0099616"(extrinsic component of matrix side of mitochondrial inner membrane)|interpro:IPR031568|dip:DIP-5118N	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:nCFfZbGCTvRYaXhQ4R99XblslvM9606	rogid:olrpTXf4PLFKXG++Rcnf3PlDjLM559292	intact-crc:F057A3FB5565C937|rigid:XtkcU8jqAgTu14EfwtOcBwul8ZE	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P35176	uniprotkb:Q9UMX0	intact:EBI-5458|uniprotkb:D6VST3|ensemblfungi:YDR304C	intact:EBI-741480|uniprotkb:Q8IXS9|uniprotkb:Q8N2Q3|uniprotkb:Q9H0T8|uniprotkb:Q9H3R4|uniprotkb:Q9HAZ5|intact:EBI-28967608|ensembl:ENSP00000365576|uniprotkb:Q5T6J5|uniprotkb:Q5T6J9|uniprotkb:A0A024R284	psi-mi:cypd_yeast(display_long)|uniprotkb:CPR5(gene name)|psi-mi:CPR5(display_short)|uniprotkb:YDR304C(locus name)|uniprotkb:D9740.14(orf name)|uniprotkb:CYP5(gene name synonym)|uniprotkb:CYPD(gene name synonym)|uniprotkb:Cyclophilin D(gene name synonym)|uniprotkb:Rotamase D(gene name synonym)	psi-mi:ubql1_human(display_long)|uniprotkb:Protein linking IAP with cytoskeleton 1(gene name synonym)|uniprotkb:UBQLN1(gene name)|psi-mi:UBQLN1(display_short)|uniprotkb:DA41(gene name synonym)|uniprotkb:PLIC1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11555036|imex:IM-24995-4330	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002712|refseq:NP_010590.3|dip:DIP-5222N|mint:P35176|ensemblfungi:YDR304C(gene)|ensemblfungi:YDR304C_mRNA(transcript)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006457"(protein folding)|go:"GO:0016018"(cyclosporin A binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|interpro:IPR020892|interpro:IPR029000	ensembl:ENST00000257468|ensembl:ENSP00000257468|ensembl:ENSP00000365576|ensembl:ENSG00000135018(gene)|ensembl:ENST00000376395(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000502"(proteasome complex)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016235"(aggresome)|go:"GO:0016236"(macroautophagy)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0019900"(kinase binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035973"(aggrephagy)|go:"GO:0042802"(identical protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0097352"(autophagosome maturation)|go:"GO:1901340"(negative regulation of store-operated calcium channel activity)|go:"GO:1902175"(regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)|interpro:IPR000626(Ubiquitin)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR028430|interpro:IPR029071|mint:Q9UMX0|rcsb pdb:2JY5|rcsb pdb:2JY6|rcsb pdb:2KLC|reactome:R-HSA-8856825|refseq:NP_038466.2|refseq:NP_444295.1|dip:DIP-41629N	-	crc64:F4861424C8443B58	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:aCn3loYoSVWfy5Tb5i+MsOHcUEo559292	rogid:nCFfZbGCTvRYaXhQ4R99XblslvM9606	intact-crc:512A542E1A3DC615|rigid:YcVJPAT45FfmKo8R3+pr/TEAB2w	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P13130	uniprotkb:Q9UMX0	intact:EBI-11523294|uniprotkb:D3DL88|ensemblfungi:YHR139C	intact:EBI-741480|uniprotkb:Q8IXS9|uniprotkb:Q8N2Q3|uniprotkb:Q9H0T8|uniprotkb:Q9H3R4|uniprotkb:Q9HAZ5|intact:EBI-28967608|ensembl:ENSP00000365576|uniprotkb:Q5T6J5|uniprotkb:Q5T6J9|uniprotkb:A0A024R284	psi-mi:ss100_yeast(display_long)|uniprotkb:SPS100(gene name)|psi-mi:SPS100(display_short)|uniprotkb:YHR139C(locus name)	psi-mi:ubql1_human(display_long)|uniprotkb:Protein linking IAP with cytoskeleton 1(gene name synonym)|uniprotkb:UBQLN1(gene name)|psi-mi:UBQLN1(display_short)|uniprotkb:DA41(gene name synonym)|uniprotkb:PLIC1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11555040|imex:IM-24995-4331	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR006034(Asparaginase/glutaminase)|refseq:NP_012007.1|sgd:S000001181|ensemblfungi:YHR139C(gene)|ensemblfungi:YHR139C_mRNA(transcript)|go:"GO:0030476"(ascospore wall assembly)|interpro:IPR036152	ensembl:ENST00000257468|ensembl:ENSP00000257468|ensembl:ENSP00000365576|ensembl:ENSG00000135018(gene)|ensembl:ENST00000376395(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000502"(proteasome complex)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016235"(aggresome)|go:"GO:0016236"(macroautophagy)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0019900"(kinase binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035973"(aggrephagy)|go:"GO:0042802"(identical protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0097352"(autophagosome maturation)|go:"GO:1901340"(negative regulation of store-operated calcium channel activity)|go:"GO:1902175"(regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)|interpro:IPR000626(Ubiquitin)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR028430|interpro:IPR029071|mint:Q9UMX0|rcsb pdb:2JY5|rcsb pdb:2JY6|rcsb pdb:2KLC|reactome:R-HSA-8856825|refseq:NP_038466.2|refseq:NP_444295.1|dip:DIP-41629N	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/03/16	rogid:ThKMilyLHPEAiJu+3ty4DXcUEE4559292	rogid:nCFfZbGCTvRYaXhQ4R99XblslvM9606	intact-crc:75E3D135ABFAD394|rigid:KGsi58uLomNB8/QsHP3n0SrQW/M	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P40325	uniprotkb:Q9UMX0	intact:EBI-23614|uniprotkb:D6VV46|ensemblfungi:YGR268C	intact:EBI-741480|uniprotkb:Q8IXS9|uniprotkb:Q8N2Q3|uniprotkb:Q9H0T8|uniprotkb:Q9H3R4|uniprotkb:Q9HAZ5|intact:EBI-28967608|ensembl:ENSP00000365576|uniprotkb:Q5T6J5|uniprotkb:Q5T6J9|uniprotkb:A0A024R284	psi-mi:hua1_yeast(display_long)|uniprotkb:HUA1(gene name)|psi-mi:HUA1(display_short)|uniprotkb:YGR268C(locus name)	psi-mi:ubql1_human(display_long)|uniprotkb:Protein linking IAP with cytoskeleton 1(gene name synonym)|uniprotkb:UBQLN1(gene name)|psi-mi:UBQLN1(display_short)|uniprotkb:DA41(gene name synonym)|uniprotkb:PLIC1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11555044|imex:IM-24995-4332	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003500|refseq:NP_011784.3|dip:DIP-1987N|ensemblfungi:YGR268C(gene)|ensemblfungi:YGR268C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|interpro:IPR038910	ensembl:ENST00000257468|ensembl:ENSP00000257468|ensembl:ENSP00000365576|ensembl:ENSG00000135018(gene)|ensembl:ENST00000376395(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000502"(proteasome complex)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016235"(aggresome)|go:"GO:0016236"(macroautophagy)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0019900"(kinase binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035973"(aggrephagy)|go:"GO:0042802"(identical protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0097352"(autophagosome maturation)|go:"GO:1901340"(negative regulation of store-operated calcium channel activity)|go:"GO:1902175"(regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)|interpro:IPR000626(Ubiquitin)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR028430|interpro:IPR029071|mint:Q9UMX0|rcsb pdb:2JY5|rcsb pdb:2JY6|rcsb pdb:2KLC|reactome:R-HSA-8856825|refseq:NP_038466.2|refseq:NP_444295.1|dip:DIP-41629N	-	crc64:78029FD484168793	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:xliNG9XUWbYRd0Nbu+xzCgxNrAs559292	rogid:nCFfZbGCTvRYaXhQ4R99XblslvM9606	intact-crc:14705A6513635771|rigid:MJOj4t/4plp19fbfmUPOCxunltg	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q04712	uniprotkb:Q9UPY8	intact:EBI-27790|uniprotkb:D6VZD2|ensemblfungi:YML043C	intact:EBI-726739|uniprotkb:O00265|uniprotkb:Q6FI15|uniprotkb:Q9BZP7|uniprotkb:Q9BZP8|uniprotkb:B7WPK5|uniprotkb:Q6FHB0|ensembl:ENSP00000233121	psi-mi:rrn11_yeast(display_long)|uniprotkb:YM9827.09C(orf name)|uniprotkb:YML043C(locus name)|uniprotkb:RRN11(gene name)|psi-mi:RRN11(display_short)	psi-mi:mare3_human(display_long)|uniprotkb:End-binding protein 3(gene name synonym)|uniprotkb:EB1 protein family member 3(gene name synonym)|uniprotkb:RP3(gene name synonym)|uniprotkb:MAPRE3(gene name)|psi-mi:MAPRE3(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11555076|imex:IM-24995-4340	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013669.1|sgd:S000004507|dip:DIP-4542N|mint:Q04712|ensemblfungi:YML043C(gene)|ensemblfungi:YML043C_mRNA(transcript)|go:"GO:0001164"(RNA polymerase I core promoter sequence-specific DNA binding)|go:"GO:0001181"(RNA polymerase I general transcription initiation factor activity)|go:"GO:0005730"(nucleolus)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0042790"(nucleolar large rRNA transcription by RNA polymerase I)|go:"GO:0070860"(RNA polymerase I core factor complex)|interpro:IPR007224(RNA polymerase I specific initiation factor)|interpro:IPR016850(Core factor complex, Rrn11 component)|rcsb pdb:5N5Y|rcsb pdb:5N5Z|rcsb pdb:5N60|rcsb pdb:5N61|rcsb pdb:5O7X|rcsb pdb:5OA1|rcsb pdb:5W5Y|rcsb pdb:5W64|rcsb pdb:5W65|rcsb pdb:5W66|rcsb pdb:6RQH|rcsb pdb:6RQL|rcsb pdb:6RRD|rcsb pdb:6RUI|rcsb pdb:6RUO|rcsb pdb:6RWE|rcsb pdb:6TPS	refseq:NP_036458.2|refseq:XP_016859086.1|refseq:NP_001289979.1|refseq:XP_006712030.1|refseq:XP_011531002.1|dip:DIP-56069N|ensembl:ENSG00000084764(gene)|ensembl:ENST00000233121(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0008017"(microtubule binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030496"(midbody)|go:"GO:0031110"(regulation of microtubule polymerization or depolymerization)|go:"GO:0031113"(regulation of microtubule polymerization)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0042802"(identical protein binding)|go:"GO:0045737"(positive regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051233"(spindle midzone)|go:"GO:0051301"(cell division)|go:"GO:1903033"(positive regulation of microtubule plus-end binding)|go:"GO:1904825"(protein localization to microtubule plus-end)|go:"GO:1905721"(mitotic spindle astral microtubule end)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR004953(EB1, C-terminal)|interpro:IPR027328|interpro:IPR027738|interpro:IPR036133|interpro:IPR036872|mint:Q9UPY8|rcsb pdb:1WYO|rcsb pdb:3CO1|rcsb pdb:3JAK|rcsb pdb:3JAL|rcsb pdb:3JAR|rcsb pdb:3TQ7	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:HeXVovHQGBfbg6FbSkFO9/T64hE559292	rogid:LHuufxyNrygS3iFW5mmg13R43NE9606	intact-crc:5567AE0178E00ED4|rigid:EFNPljGHdNbt+95Zb2JFXjKST4A	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9UPT5-1	uniprotkb:P40482	intact:EBI-6251402|ensembl:ENSP00000468404	intact:EBI-16592|ensemblfungi:YIL109C|uniprotkb:D6VVH8	psi-mi:q9upt5-1(display_long)|uniprotkb:EXOC7(gene name)|psi-mi:EXOC7(display_short)|uniprotkb:EXO70(gene name synonym)|uniprotkb:KIAA1067(gene name synonym)|uniprotkb:Exocyst complex component Exo70(gene name synonym)	psi-mi:sec24_yeast(display_long)|uniprotkb:SEC24(gene name)|psi-mi:SEC24(display_short)|uniprotkb:Abnormal nuclear morphology 1(gene name synonym)|uniprotkb:ANU1(gene name synonym)|uniprotkb:YIL109C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11555072|imex:IM-24995-4339	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000182473(gene)|ensembl:ENST00000589210(transcript)|intact:EBI-720048(isoform-parent)|uniprotkb:Q9UPT5-1(isoform-parent)	refseq:NP_012157.3|ensemblfungi:YIL109C(gene)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016236"(macroautophagy)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0070971"(endoplasmic reticulum exit site)|ensemblfungi:YIL109C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0090110"(COPII-coated vesicle cargo loading)|interpro:IPR006895(Zinc finger, Sec23/Sec24-type)|interpro:IPR006896(Sec23/Sec24 trunk region)|interpro:IPR006900(Sec23/Sec24 helical region)|interpro:IPR007123(Gelsolin region)|interpro:IPR012990(Sec23/Sec24 beta-sandwich)|interpro:IPR029006|interpro:IPR036174|interpro:IPR036175|interpro:IPR036180|go:"GO:0000149"(SNARE binding)|go:"GO:0000329"(fungal-type vacuole membrane)|interpro:IPR036465|interpro:IPR041742|rcsb pdb:1M2V|rcsb pdb:1PCX|rcsb pdb:1PD0|rcsb pdb:1PD1|rcsb pdb:4BZI|rcsb pdb:6GNI|rcsb pdb:6ZGA|reactome:R-SCE-204005|reactome:R-SCE-5694530|reactome:R-SCE-983170|go:"GO:0005048"(signal sequence binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|sgd:S000001371|dip:DIP-2233N|mint:P40482	-	-	crc64:35E2BDD24CC75899	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:CKIeTOGXIWrHA1Duuw7x1ycRPoc9606	rogid:e7ekVFzZJMZvfRUZ9Q2jDQ/hvs0559292	intact-crc:D5FE35B16C4B8719|rigid:2Mrw3Ks+1DL9VaeNNYSumHGSw9g	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9UNE7	uniprotkb:P32502	intact:EBI-357085|uniprotkb:O60526|uniprotkb:Q969U2|uniprotkb:Q9HBT1|uniprotkb:A2IDB9|ensembl:ENSP00000219548	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:chip_human(display_long)|uniprotkb:CHIP(gene name synonym)|uniprotkb:STUB1(gene name)|psi-mi:STUB1(display_short)|uniprotkb:PP1131(orf name)|uniprotkb:Carboxy terminus of Hsp70-interacting protein(gene name synonym)|uniprotkb:STIP1 homology and U box-containing protein 1(gene name synonym)|uniprotkb:CLL-associated antigen KW-8(gene name synonym)|uniprotkb:Antigen NY-CO-7(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase CHIP(gene name synonym)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11555056|imex:IM-24995-4335	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-29752N|refseq:NP_005852.2|refseq:NP_001280126.1|ensembl:ENSG00000103266(gene)|ensembl:ENST00000219548(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0002931"(response to ischemia)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030911"(TPR domain binding)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031371"(ubiquitin conjugating enzyme complex)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031943"(regulation of glucocorticoid metabolic process)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|go:"GO:0034605"(cellular response to heat)|go:"GO:0038128"(ERBB2 signaling pathway)|go:"GO:0042405"(nuclear inclusion body)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0046332"(SMAD binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0051604"(protein maturation)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0030579"(ubiquitin-dependent SMAD protein catabolic process)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061684"(chaperone-mediated autophagy)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0071218"(cellular response to misfolded protein)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0090035"(positive regulation of chaperone-mediated protein complex assembly)|go:"GO:0101031"(chaperone complex)|interpro:IPR003613(U box)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019734|interpro:IPR041312|mint:Q9UNE7|rcsb pdb:4KBQ|rcsb pdb:6EFK|rcsb pdb:6NSV|reactome:R-HSA-2173788|reactome:R-HSA-5213460|reactome:R-HSA-5675482|reactome:R-HSA-8863795|reactome:R-HSA-8939902|reactome:R-HSA-8948751|reactome:R-HSA-983168	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731	-	-	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:h4QyIM0TptgkQppPUgiKn68XjP49606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:9EA7DC7AAE07EA14|rigid:zTTDiLY+4UF0EULVlTU2BY5Jh4s	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P53933	uniprotkb:Q9UNF0	intact:EBI-28798|uniprotkb:D6W186|ensemblfungi:YNL094W	intact:EBI-742503|uniprotkb:O95921|uniprotkb:Q96HV9|uniprotkb:Q9H0D3|uniprotkb:Q9NPN1|uniprotkb:Q9Y4V2|ensembl:ENSP00000385040|ensembl:ENSP00000385372|ensembl:ENSP00000263246	psi-mi:app1_yeast(display_long)|uniprotkb:APP1(gene name)|psi-mi:APP1(display_short)|uniprotkb:Actin patch protein 1(gene name synonym)|uniprotkb:N2219(orf name)|uniprotkb:YNL094W(locus name)	psi-mi:pacn2_human(display_long)|uniprotkb:PACSIN2(gene name)|psi-mi:PACSIN2(display_short)|uniprotkb:Syndapin-II(gene name synonym)|uniprotkb:Syndapin-2(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11555064|imex:IM-24995-4337	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014305.1|sgd:S000005038|dip:DIP-2006N|mint:P53933|ensemblfungi:YNL094W(gene)|ensemblfungi:YNL094W_mRNA(transcript)|go:"GO:0008195"(phosphatidate phosphatase activity)|go:"GO:0030479"(actin cortical patch)|go:"GO:0044255"(cellular lipid metabolic process)|interpro:IPR017210(Uncharacterised conserved protein UCP037464, actin patch protein 1)|interpro:IPR019236	refseq:NP_001171899.1|refseq:NP_001171900.1|refseq:NP_009160.2|refseq:XP_005261376.1|refseq:XP_016884053.1|ensembl:ENST00000263246(transcript)|ensembl:ENST00000402229(transcript)|ensembl:ENST00000403744(transcript)|go:"GO:0005215"(transporter activity)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|ensembl:ENSG00000100266(gene)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0032587"(ruffle membrane)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045296"(cadherin binding)|go:"GO:0045806"(negative regulation of endocytosis)|go:"GO:0048858"(cell projection morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070300"(phosphatidic acid binding)|go:"GO:0070836"(caveola assembly)|go:"GO:0072584"(caveolin-mediated endocytosis)|go:"GO:0097320"(plasma membrane tubulation)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR027267|interpro:IPR028521|interpro:IPR031160|interpro:IPR035743|interpro:IPR036028|interpro:IPR037453|mint:Q9UNF0|rcsb pdb:3ABH|rcsb pdb:3ACO|rcsb pdb:3HAJ|rcsb pdb:3Q0K|reactome:R-HSA-8856828	-	crc64:B85C525548BA34BC	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:4ORrWVN2DOL+59LI2qWcKYYVfcE559292	rogid:oEGsyQlsPg61RRGLjBdPGKDmkXc9606	intact-crc:4DAA426F7160CFCE|rigid:NP6BsaMOKux/N0SroiC1XlUAyrw	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P38247	uniprotkb:Q9UNE7	intact:EBI-21507|uniprotkb:D6VQ76|ensemblfungi:YBR077C	intact:EBI-357085|uniprotkb:O60526|uniprotkb:Q969U2|uniprotkb:Q9HBT1|uniprotkb:A2IDB9|ensembl:ENSP00000219548	psi-mi:slm4_yeast(display_long)|uniprotkb:YBR077C(locus name)|uniprotkb:YBR0723(orf name)|uniprotkb:GSE complex subunit 1(gene name synonym)|uniprotkb:EGO complex subunit 3(gene name synonym)|uniprotkb:SLM4(gene name)|psi-mi:SLM4(display_short)|uniprotkb:EGO3(gene name synonym)|uniprotkb:GSE1(gene name synonym)	psi-mi:chip_human(display_long)|uniprotkb:CHIP(gene name synonym)|uniprotkb:STUB1(gene name)|psi-mi:STUB1(display_short)|uniprotkb:PP1131(orf name)|uniprotkb:Carboxy terminus of Hsp70-interacting protein(gene name synonym)|uniprotkb:STIP1 homology and U box-containing protein 1(gene name synonym)|uniprotkb:CLL-associated antigen KW-8(gene name synonym)|uniprotkb:Antigen NY-CO-7(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase CHIP(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11555060|imex:IM-24995-4336	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009633.3|sgd:S000000281|mint:P38247|dip:DIP-1763N|ensemblfungi:YBR077C(gene)|ensemblfungi:YBR077C_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0007165"(signal transduction)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016237"(lysosomal microautophagy)|go:"GO:0031902"(late endosome membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0071986"(Ragulator complex)|interpro:IPR020233|rcsb pdb:3LGO|rcsb pdb:4FTX|rcsb pdb:4FUW|rcsb pdb:4XPM|rcsb pdb:6JWP	dip:DIP-29752N|refseq:NP_005852.2|refseq:NP_001280126.1|ensembl:ENSG00000103266(gene)|ensembl:ENST00000219548(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0002931"(response to ischemia)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030911"(TPR domain binding)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031371"(ubiquitin conjugating enzyme complex)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031943"(regulation of glucocorticoid metabolic process)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|go:"GO:0034605"(cellular response to heat)|go:"GO:0038128"(ERBB2 signaling pathway)|go:"GO:0042405"(nuclear inclusion body)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0046332"(SMAD binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0051604"(protein maturation)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0030579"(ubiquitin-dependent SMAD protein catabolic process)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061684"(chaperone-mediated autophagy)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0071218"(cellular response to misfolded protein)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0090035"(positive regulation of chaperone-mediated protein complex assembly)|go:"GO:0101031"(chaperone complex)|interpro:IPR003613(U box)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019734|interpro:IPR041312|mint:Q9UNE7|rcsb pdb:4KBQ|rcsb pdb:6EFK|rcsb pdb:6NSV|reactome:R-HSA-2173788|reactome:R-HSA-5213460|reactome:R-HSA-5675482|reactome:R-HSA-8863795|reactome:R-HSA-8939902|reactome:R-HSA-8948751|reactome:R-HSA-983168	-	crc64:D64ABDE1CDF265FD	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:BCEWjA3PQvwm3n08QwY0D//TpbA559292	rogid:h4QyIM0TptgkQppPUgiKn68XjP49606	intact-crc:9782CD648E2481F3|rigid:iLCs6fLjNe3KPIp16E3mT4+dQwM	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P69851	uniprotkb:Q9UPT5-1	intact:EBI-975389|uniprotkb:D6VSV2|ensemblfungi:YDR320C-A	intact:EBI-6251402|ensembl:ENSP00000468404	psi-mi:dad4_yeast(display_long)|uniprotkb:Outer kinetochore protein DAD4(gene name synonym)|uniprotkb:DUO1 and DAM1-interacting protein 4(gene name synonym)|uniprotkb:Helper of ASK1 protein 2(gene name synonym)|uniprotkb:DAD4(gene name)|psi-mi:DAD4(display_short)|uniprotkb:HSK2(gene name synonym)|uniprotkb:YDR320C-A(locus name)	psi-mi:q9upt5-1(display_long)|uniprotkb:EXOC7(gene name)|psi-mi:EXOC7(display_short)|uniprotkb:EXO70(gene name synonym)|uniprotkb:KIAA1067(gene name synonym)|uniprotkb:Exocyst complex component Exo70(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11555068|imex:IM-24995-4338	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YDR320C-A(gene)|ensemblfungi:YDR320C-A_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0008608"(attachment of spindle microtubules to kinetochore)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0042729"(DASH complex)|go:"GO:0051301"(cell division)|go:"GO:0051987"(positive regulation of attachment of spindle microtubules to kinetochore)|go:"GO:0072686"(mitotic spindle)|sgd:S000007604|interpro:IPR013959(DASH complex, subunit Dad4)|refseq:NP_710144.3|mint:P69851	ensembl:ENSG00000182473(gene)|ensembl:ENST00000589210(transcript)|intact:EBI-720048(isoform-parent)|uniprotkb:Q9UPT5-1(isoform-parent)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:P+GXHuoP14//+W2vOt26MEdTBNo559292	rogid:CKIeTOGXIWrHA1Duuw7x1ycRPoc9606	intact-crc:C4CE9F939DEBEA85|rigid:Dz3cuiQPy1CeDZl+jtjPoiO0azk	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P38340	uniprotkb:Q9Y281	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-351218|uniprotkb:G3V5P4|ensembl:ENSP00000298159|ensembl:ENSP00000340635|ensembl:ENSP00000500375|ensembl:ENSP00000500532	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:cof2_human(display_long)|uniprotkb:CFL2(gene name)|psi-mi:CFL2(display_short)|uniprotkb:Cofilin, muscle isoform(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11555096|imex:IM-24995-4345	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F	refseq:NP_068733.1|refseq:NP_619579.1|refseq:XP_011534665.1|refseq:NP_001230574.1|dip:DIP-33178N|ensembl:ENSG00000165410(gene)|ensembl:ENST00000298159(transcript)|ensembl:ENST00000341223(transcript)|ensembl:ENST00000672163(transcript)|ensembl:ENST00000672517(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016363"(nuclear matrix)|go:"GO:0030018"(Z disc)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030043"(actin filament fragmentation)|go:"GO:0030836"(positive regulation of actin filament depolymerization)|go:"GO:0031674"(I band)|go:"GO:0045214"(sarcomere organization)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0048870"(cell motility)|go:"GO:0051014"(actin filament severing)|go:"GO:0051015"(actin filament binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002108(Actin-binding, cofilin/tropomyosin type)|interpro:IPR017904|interpro:IPR029006|mint:Q9Y281	-	crc64:66699F37B0013088	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:HwYoUPZRkuRzqMLvuQctwNCOREA9606	intact-crc:DC49207EE03BE75A|rigid:dkDxg6oyNPMCnLXoGQkGZlDBp1E	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P46680	uniprotkb:Q9Y281	intact:EBI-2406|uniprotkb:D6VZR5|ensemblfungi:YMR092C	intact:EBI-351218|uniprotkb:G3V5P4|ensembl:ENSP00000298159|ensembl:ENSP00000340635|ensembl:ENSP00000500375|ensembl:ENSP00000500532	psi-mi:aip1_yeast(display_long)|uniprotkb:AIP1(gene name)|psi-mi:AIP1(display_short)|uniprotkb:YM9582.17C(orf name)|uniprotkb:YMR092C(locus name)	psi-mi:cof2_human(display_long)|uniprotkb:CFL2(gene name)|psi-mi:CFL2(display_short)|uniprotkb:Cofilin, muscle isoform(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11555092|imex:IM-24995-4344	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013810.1|sgd:S000004698|reactome:R-SCE-114608|dip:DIP-890N|ensemblfungi:YMR092C(gene)|ensemblfungi:YMR092C_mRNA(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005884"(actin filament)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030479"(actin cortical patch)|go:"GO:0030836"(positive regulation of actin filament depolymerization)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032466"(negative regulation of cytokinesis)|go:"GO:0043332"(mating projection tip)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|rcsb pdb:1PGU|rcsb pdb:1PI6	refseq:NP_068733.1|refseq:NP_619579.1|refseq:XP_011534665.1|refseq:NP_001230574.1|dip:DIP-33178N|ensembl:ENSG00000165410(gene)|ensembl:ENST00000298159(transcript)|ensembl:ENST00000341223(transcript)|ensembl:ENST00000672163(transcript)|ensembl:ENST00000672517(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016363"(nuclear matrix)|go:"GO:0030018"(Z disc)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030043"(actin filament fragmentation)|go:"GO:0030836"(positive regulation of actin filament depolymerization)|go:"GO:0031674"(I band)|go:"GO:0045214"(sarcomere organization)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0048870"(cell motility)|go:"GO:0051014"(actin filament severing)|go:"GO:0051015"(actin filament binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002108(Actin-binding, cofilin/tropomyosin type)|interpro:IPR017904|interpro:IPR029006|mint:Q9Y281	-	crc64:B8340BF68DD08257	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:TwLC/U+xqc7crYws+782F2f1rEo559292	rogid:HwYoUPZRkuRzqMLvuQctwNCOREA9606	intact-crc:C878FCE608C9975E|rigid:3XBdOAwfyGwKG/zP3T5emtfdSgk	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9UPY8	uniprotkb:P32502	intact:EBI-726739|uniprotkb:O00265|uniprotkb:Q6FI15|uniprotkb:Q9BZP7|uniprotkb:Q9BZP8|uniprotkb:B7WPK5|uniprotkb:Q6FHB0|ensembl:ENSP00000233121	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:mare3_human(display_long)|uniprotkb:End-binding protein 3(gene name synonym)|uniprotkb:EB1 protein family member 3(gene name synonym)|uniprotkb:RP3(gene name synonym)|uniprotkb:MAPRE3(gene name)|psi-mi:MAPRE3(display_short)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11555080|imex:IM-24995-4341	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_036458.2|refseq:XP_016859086.1|refseq:NP_001289979.1|refseq:XP_006712030.1|refseq:XP_011531002.1|dip:DIP-56069N|ensembl:ENSG00000084764(gene)|ensembl:ENST00000233121(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0008017"(microtubule binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030496"(midbody)|go:"GO:0031110"(regulation of microtubule polymerization or depolymerization)|go:"GO:0031113"(regulation of microtubule polymerization)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0042802"(identical protein binding)|go:"GO:0045737"(positive regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051233"(spindle midzone)|go:"GO:0051301"(cell division)|go:"GO:1903033"(positive regulation of microtubule plus-end binding)|go:"GO:1904825"(protein localization to microtubule plus-end)|go:"GO:1905721"(mitotic spindle astral microtubule end)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR004953(EB1, C-terminal)|interpro:IPR027328|interpro:IPR027738|interpro:IPR036133|interpro:IPR036872|mint:Q9UPY8|rcsb pdb:1WYO|rcsb pdb:3CO1|rcsb pdb:3JAK|rcsb pdb:3JAL|rcsb pdb:3JAR|rcsb pdb:3TQ7	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731	-	-	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:LHuufxyNrygS3iFW5mmg13R43NE9606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:E646F87F23F137BA|rigid:pcUI+ZAYoWEoUxXaEdL9Ti4WkEA	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9UPY8	uniprotkb:P32902	intact:EBI-726739|uniprotkb:O00265|uniprotkb:Q6FI15|uniprotkb:Q9BZP7|uniprotkb:Q9BZP8|uniprotkb:B7WPK5|uniprotkb:Q6FHB0|ensembl:ENSP00000233121	intact:EBI-16248|ensemblfungi:YHL004W|uniprotkb:D3DKR0	psi-mi:mare3_human(display_long)|uniprotkb:End-binding protein 3(gene name synonym)|uniprotkb:EB1 protein family member 3(gene name synonym)|uniprotkb:RP3(gene name synonym)|uniprotkb:MAPRE3(gene name)|psi-mi:MAPRE3(display_short)	psi-mi:rt04_yeast(display_long)|uniprotkb:MRP4(gene name)|psi-mi:MRP4(display_short)|uniprotkb:MRP4A(gene name synonym)|uniprotkb:Mitochondrial small ribosomal subunit protein uS2m(gene name synonym)|uniprotkb:YHL004W(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11555084|imex:IM-24995-4342	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_036458.2|refseq:XP_016859086.1|refseq:NP_001289979.1|refseq:XP_006712030.1|refseq:XP_011531002.1|dip:DIP-56069N|ensembl:ENSG00000084764(gene)|ensembl:ENST00000233121(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0008017"(microtubule binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030496"(midbody)|go:"GO:0031110"(regulation of microtubule polymerization or depolymerization)|go:"GO:0031113"(regulation of microtubule polymerization)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0042802"(identical protein binding)|go:"GO:0045737"(positive regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051233"(spindle midzone)|go:"GO:0051301"(cell division)|go:"GO:1903033"(positive regulation of microtubule plus-end binding)|go:"GO:1904825"(protein localization to microtubule plus-end)|go:"GO:1905721"(mitotic spindle astral microtubule end)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR004953(EB1, C-terminal)|interpro:IPR027328|interpro:IPR027738|interpro:IPR036133|interpro:IPR036872|mint:Q9UPY8|rcsb pdb:1WYO|rcsb pdb:3CO1|rcsb pdb:3JAK|rcsb pdb:3JAL|rcsb pdb:3JAR|rcsb pdb:3TQ7	ensemblfungi:YHL004W(gene)|ensemblfungi:YHL004W_mRNA(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR001865(Ribosomal protein S2)|interpro:IPR005706(Ribosomal protein S2, bacterial-type)|interpro:IPR018130|interpro:IPR023591|rcsb pdb:5MRC|rcsb pdb:5MRE|rcsb pdb:5MRF|refseq:NP_011859.1|sgd:S000000996|dip:DIP-5035N|mint:P32902	-	-	crc64:81A1CB33134BC559	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:LHuufxyNrygS3iFW5mmg13R43NE9606	rogid:BlL3W6HUN+uAKF/AxwlV1zT5YZQ559292	intact-crc:DB1E0F6DE0343D93|rigid:y7KhdkY3BxPcBy0QUN8WFq2gJzU	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:G5E962	uniprotkb:Q9URQ5	intact:EBI-11525615|ensembl:ENSP00000328177	intact:EBI-8717|ensemblfungi:YCR020W-B|uniprotkb:D6VR30	psi-mi:g5e962_human(display_long)|uniprotkb:hCG_1644200(orf name)|uniprotkb:MAGEA11(gene name)|psi-mi:MAGEA11(display_short)	psi-mi:htl1_yeast(display_long)|uniprotkb:YCR020W-B(locus name)|uniprotkb:HTL1(gene name)|psi-mi:HTL1(display_short)|uniprotkb:DRT1(gene name synonym)|uniprotkb:Chromatin structure-remodeling complex protein HTL1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11555088|imex:IM-24995-4343	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001011544.1|ensembl:ENSG00000185247(gene)|ensembl:ENST00000333104(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016604"(nuclear body)|interpro:IPR002190(MAGE protein)|interpro:IPR021072|interpro:IPR030099|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899	go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016586"(RSC-type complex)|rcsb pdb:6K15|rcsb pdb:6KW3|rcsb pdb:6KW4|rcsb pdb:6KW5|rcsb pdb:6TDA|rcsb pdb:6V8O|ensemblfungi:YCR020W-B(gene)|ensemblfungi:YCR020W-B_mRNA(transcript)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0005634"(nucleus)|rcsb pdb:6V92|refseq:NP_009949.1|sgd:S000006439|mint:Q9URQ5	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:sVB0aA6yibWUx/d2SE+pwpKKgtI9606	rogid:Le5HdUusNnY+/Cgn/WyISowVdbs559292	intact-crc:FA1D0A82CC7C686A|rigid:MnNibLqcnWogRNb0/1fThCATswY	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9Y2D8	uniprotkb:Q04712	intact:EBI-2212028|uniprotkb:B4DFE3|uniprotkb:J3KR02|uniprotkb:A8K8W0|uniprotkb:D3DT13|uniprotkb:Q6P2P8|uniprotkb:Q6ULS1|uniprotkb:Q7L168|uniprotkb:Q9UIX0|intact:EBI-10964529|ensembl:ENSP00000340279	intact:EBI-27790|uniprotkb:D6VZD2|ensemblfungi:YML043C	psi-mi:adip_human(display_long)|uniprotkb:SSX2IP(gene name)|psi-mi:SSX2IP(display_short)|uniprotkb:KIAA0923(gene name synonym)|uniprotkb:Afadin DIL domain-interacting protein(gene name synonym)|uniprotkb:SSX2-interacting protein(gene name synonym)	psi-mi:rrn11_yeast(display_long)|uniprotkb:YM9827.09C(orf name)|uniprotkb:YML043C(locus name)|uniprotkb:RRN11(gene name)|psi-mi:RRN11(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11555116|imex:IM-24995-4350	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011538912.1|refseq:NP_001159765.1|refseq:NP_001159766.1|refseq:NP_001159767.1|refseq:NP_001159889.1|refseq:NP_054740.3|refseq:XP_005270484.1|refseq:XP_005270485.1|refseq:XP_006710394.1|refseq:XP_016855723.1|ensembl:ENSG00000117155(gene)|ensembl:ENST00000342203(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005912"(adherens junction)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031252"(cell leading edge)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0035735"(intraciliary transport involved in cilium assembly)|go:"GO:0036064"(ciliary basal body)|go:"GO:0060271"(cilium assembly)|go:"GO:2000145"(regulation of cell motility)|interpro:IPR021622|mint:Q9Y2D8	refseq:NP_013669.1|sgd:S000004507|dip:DIP-4542N|mint:Q04712|ensemblfungi:YML043C(gene)|ensemblfungi:YML043C_mRNA(transcript)|go:"GO:0001164"(RNA polymerase I core promoter sequence-specific DNA binding)|go:"GO:0001181"(RNA polymerase I general transcription initiation factor activity)|go:"GO:0005730"(nucleolus)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0042790"(nucleolar large rRNA transcription by RNA polymerase I)|go:"GO:0070860"(RNA polymerase I core factor complex)|interpro:IPR007224(RNA polymerase I specific initiation factor)|interpro:IPR016850(Core factor complex, Rrn11 component)|rcsb pdb:5N5Y|rcsb pdb:5N5Z|rcsb pdb:5N60|rcsb pdb:5N61|rcsb pdb:5O7X|rcsb pdb:5OA1|rcsb pdb:5W5Y|rcsb pdb:5W64|rcsb pdb:5W65|rcsb pdb:5W66|rcsb pdb:6RQH|rcsb pdb:6RQL|rcsb pdb:6RRD|rcsb pdb:6RUI|rcsb pdb:6RUO|rcsb pdb:6RWE|rcsb pdb:6TPS	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:E0VeMRF9SrpQKSJFP01XEbMjeF89606	rogid:HeXVovHQGBfbg6FbSkFO9/T64hE559292	intact-crc:ACB52ED177BE8CB0|rigid:b6xKGsfdNTImjel1uUuhs1+q4Gs	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9Y2D8	uniprotkb:Q12259	intact:EBI-2212028|uniprotkb:B4DFE3|uniprotkb:J3KR02|uniprotkb:A8K8W0|uniprotkb:D3DT13|uniprotkb:Q6P2P8|uniprotkb:Q6ULS1|uniprotkb:Q7L168|uniprotkb:Q9UIX0|intact:EBI-10964529|ensembl:ENSP00000340279	intact:EBI-30776|uniprotkb:D6VYA8|ensemblfungi:YLR108C	psi-mi:adip_human(display_long)|uniprotkb:SSX2IP(gene name)|psi-mi:SSX2IP(display_short)|uniprotkb:KIAA0923(gene name synonym)|uniprotkb:Afadin DIL domain-interacting protein(gene name synonym)|uniprotkb:SSX2-interacting protein(gene name synonym)	psi-mi:yl108_yeast(display_long)|uniprotkb:L2913(orf name)|uniprotkb:YLR108C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11555112|imex:IM-24995-4349	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011538912.1|refseq:NP_001159765.1|refseq:NP_001159766.1|refseq:NP_001159767.1|refseq:NP_001159889.1|refseq:NP_054740.3|refseq:XP_005270484.1|refseq:XP_005270485.1|refseq:XP_006710394.1|refseq:XP_016855723.1|ensembl:ENSG00000117155(gene)|ensembl:ENST00000342203(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005912"(adherens junction)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031252"(cell leading edge)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0035735"(intraciliary transport involved in cilium assembly)|go:"GO:0036064"(ciliary basal body)|go:"GO:0060271"(cilium assembly)|go:"GO:2000145"(regulation of cell motility)|interpro:IPR021622|mint:Q9Y2D8	refseq:NP_013209.1|sgd:S000004098|dip:DIP-4075N|ensemblfungi:YLR108C(gene)|ensemblfungi:YLR108C_mRNA(transcript)|go:"GO:0005634"(nucleus)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:E0VeMRF9SrpQKSJFP01XEbMjeF89606	rogid:CzknxXhhvgMp3J0/oi197EgZ05U559292	intact-crc:844BC45FEA5E2BFF|rigid:1VHJ2RXiv00qeKbkVSavFpLhMM0	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9Y294	uniprotkb:P02309	intact:EBI-749553|uniprotkb:Q6IA08|uniprotkb:Q9P014|ensembl:ENSP00000229595	intact:EBI-8113|uniprotkb:D6VQ10|ensemblfungi:YBR009C|ensemblfungi:YNL030W	psi-mi:asf1a_human(display_long)|uniprotkb:Anti-silencing function protein 1 homolog A(gene name synonym)|uniprotkb:CCG1-interacting factor A(gene name synonym)|uniprotkb:ASF1A(gene name)|psi-mi:ASF1A(display_short)|uniprotkb:CGI-98(orf name)|uniprotkb:HSPC146(orf name)	psi-mi:h4_yeast(display_long)|uniprotkb:N2752(orf name)|uniprotkb:YBR0122(orf name)|uniprotkb:YBR009C(locus name)|uniprotkb:YNL030W(locus name)|uniprotkb:HHF1(gene name)|psi-mi:HHF1(display_short)|uniprotkb:HHF2(gene name)|psi-mi:HHF2(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11555100|imex:IM-24995-4346	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_054753.1|dip:DIP-29241N|ensembl:ENSG00000111875(gene)|ensembl:ENST00000229595(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0042692"(muscle cell differentiation)|interpro:IPR006818(Anti-silencing protein, ASF1-like)|interpro:IPR036747|mint:Q9Y294|rcsb pdb:1TEY|rcsb pdb:2I32|rcsb pdb:2IIJ|rcsb pdb:2IO5|rcsb pdb:3AAD|rcsb pdb:5C3I|rcsb pdb:6F0G|rcsb pdb:6F0H|rcsb pdb:6ZUF|reactome:R-HSA-2559584|rcsb pdb:6F0F	refseq:NP_009563.1|refseq:NP_014368.1|sgd:S000000213|sgd:S000004975|dip:DIP-418N|mint:P02309|ensemblfungi:YBR009C(gene)|ensemblfungi:YBR009C_mRNA(transcript)|ensemblfungi:YNL030W(gene)|ensemblfungi:YNL030W_mRNA(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0006333"(chromatin assembly or disassembly)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0034729"(histone H3-K79 methylation)|go:"GO:0043935"(sexual sporulation resulting in formation of a cellular spore)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0061587"(transfer RNA gene-mediated silencing)|interpro:IPR001951(Histone H4)|interpro:IPR009072(Histone-fold)|interpro:IPR019809|interpro:IPR035425|rcsb pdb:1E6I|rcsb pdb:1ID3|rcsb pdb:1Q1A|rcsb pdb:1SZC|rcsb pdb:1SZD|rcsb pdb:2DVQ|rcsb pdb:2DVR|rcsb pdb:2E3K|rcsb pdb:2FSB|rcsb pdb:2H2H|rcsb pdb:2L5A|rcsb pdb:2QQF|rcsb pdb:2QQG|rcsb pdb:3TO6|rcsb pdb:4JJN|rcsb pdb:4KUD|rcsb pdb:4PSX|rcsb pdb:4TWI|rcsb pdb:4TWJ|rcsb pdb:5W0V|rcsb pdb:5ZBA|rcsb pdb:5ZBB|rcsb pdb:6GEJ|rcsb pdb:6GEN|rcsb pdb:6QLD|rcsb pdb:6RXJ|rcsb pdb:6RXK|rcsb pdb:6RXL|rcsb pdb:6RXM|rcsb pdb:6RXO|rcsb pdb:6RXP|rcsb pdb:6RXQ|rcsb pdb:6RXR|rcsb pdb:7K78|rcsb pdb:7K7G|reactome:R-SCE-2299718|reactome:R-SCE-2559580|reactome:R-SCE-3214842|reactome:R-SCE-3214847|reactome:R-SCE-3214858|reactome:R-SCE-4551638|reactome:R-SCE-9018519	-	caution:This sequence has been withdrawn from Uniprot.	crc64:69B7D1F89E62DE41	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:rIMptRSOYD+wfp0dMEHjhNNsHXQ9606	rogid:wGtUrumyxGKsW9BEzkBW3FwvwUo559292	intact-crc:75F331A0D9D4B0C0|rigid:CcW8ft9xR+nvB26MswK/6i200ZQ	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9Y294	uniprotkb:Q12161	intact:EBI-749553|uniprotkb:Q6IA08|uniprotkb:Q9P014|ensembl:ENSP00000229595	intact:EBI-34372|uniprotkb:D6W213|ensemblfungi:YOL054W	psi-mi:asf1a_human(display_long)|uniprotkb:Anti-silencing function protein 1 homolog A(gene name synonym)|uniprotkb:CCG1-interacting factor A(gene name synonym)|uniprotkb:ASF1A(gene name)|psi-mi:ASF1A(display_short)|uniprotkb:CGI-98(orf name)|uniprotkb:HSPC146(orf name)	psi-mi:psh1_yeast(display_long)|uniprotkb:PSH1(gene name)|psi-mi:PSH1(display_short)|uniprotkb:POB3/SPT16 histone-associated protein 1(gene name synonym)|uniprotkb:O1263(orf name)|uniprotkb:YOL054W(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11555104|imex:IM-24995-4347	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_054753.1|dip:DIP-29241N|ensembl:ENSG00000111875(gene)|ensembl:ENST00000229595(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0042692"(muscle cell differentiation)|interpro:IPR006818(Anti-silencing protein, ASF1-like)|interpro:IPR036747|mint:Q9Y294|rcsb pdb:1TEY|rcsb pdb:2I32|rcsb pdb:2IIJ|rcsb pdb:2IO5|rcsb pdb:3AAD|rcsb pdb:5C3I|rcsb pdb:6F0G|rcsb pdb:6F0H|rcsb pdb:6ZUF|reactome:R-HSA-2559584|rcsb pdb:6F0F	refseq:NP_014587.1|sgd:S000005415|mint:Q12161|dip:DIP-6481N|ensemblfungi:YOL054W(gene)|ensemblfungi:YOL054W_mRNA(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907	-	caution:This sequence has been withdrawn from Uniprot.	crc64:CE0ECBCB6D465554	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:rIMptRSOYD+wfp0dMEHjhNNsHXQ9606	rogid:AvPMRd/GjfaTyQjEfMPhBVcvOs4559292	intact-crc:A9C74F56BE140391|rigid:yPa4Yh8Wg9LcdUz1Ez3K/7ckA9M	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9Y2D8	uniprotkb:P32502	intact:EBI-2212028|uniprotkb:B4DFE3|uniprotkb:J3KR02|uniprotkb:A8K8W0|uniprotkb:D3DT13|uniprotkb:Q6P2P8|uniprotkb:Q6ULS1|uniprotkb:Q7L168|uniprotkb:Q9UIX0|intact:EBI-10964529|ensembl:ENSP00000340279	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:adip_human(display_long)|uniprotkb:SSX2IP(gene name)|psi-mi:SSX2IP(display_short)|uniprotkb:KIAA0923(gene name synonym)|uniprotkb:Afadin DIL domain-interacting protein(gene name synonym)|uniprotkb:SSX2-interacting protein(gene name synonym)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11555108|imex:IM-24995-4348	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011538912.1|refseq:NP_001159765.1|refseq:NP_001159766.1|refseq:NP_001159767.1|refseq:NP_001159889.1|refseq:NP_054740.3|refseq:XP_005270484.1|refseq:XP_005270485.1|refseq:XP_006710394.1|refseq:XP_016855723.1|ensembl:ENSG00000117155(gene)|ensembl:ENST00000342203(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005912"(adherens junction)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031252"(cell leading edge)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0035735"(intraciliary transport involved in cilium assembly)|go:"GO:0036064"(ciliary basal body)|go:"GO:0060271"(cilium assembly)|go:"GO:2000145"(regulation of cell motility)|interpro:IPR021622|mint:Q9Y2D8	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731	-	-	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:E0VeMRF9SrpQKSJFP01XEbMjeF89606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:057463E34B87B187|rigid:RUc60KIbnAdYEr1IMFPesdm94Xs	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P40498	uniprotkb:Q9Y2D8	intact:EBI-25113|uniprotkb:D6VVJ6|ensemblfungi:YIL091C	intact:EBI-2212028|uniprotkb:B4DFE3|uniprotkb:J3KR02|uniprotkb:A8K8W0|uniprotkb:D3DT13|uniprotkb:Q6P2P8|uniprotkb:Q6ULS1|uniprotkb:Q7L168|uniprotkb:Q9UIX0|intact:EBI-10964529|ensembl:ENSP00000340279	psi-mi:utp25_yeast(display_long)|uniprotkb:YIL091C(locus name)|uniprotkb:UTP25(gene name)|psi-mi:UTP25(display_short)|uniprotkb:U three protein 25(gene name synonym)	psi-mi:adip_human(display_long)|uniprotkb:SSX2IP(gene name)|psi-mi:SSX2IP(display_short)|uniprotkb:KIAA0923(gene name synonym)|uniprotkb:Afadin DIL domain-interacting protein(gene name synonym)|uniprotkb:SSX2-interacting protein(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11555132|imex:IM-24995-4354	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012175.1|sgd:S000001353|mint:P40498|dip:DIP-5629N|ensemblfungi:YIL091C(gene)|ensemblfungi:YIL091C_mRNA(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0019843"(rRNA binding)|go:"GO:0032040"(small-subunit processome)|go:"GO:0034511"(U3 snoRNA binding)|go:"GO:0042274"(ribosomal small subunit biogenesis)|interpro:IPR010678(Protein of unknown function DUF1253)|interpro:IPR027417|reactome:R-SCE-6791226	refseq:XP_011538912.1|refseq:NP_001159765.1|refseq:NP_001159766.1|refseq:NP_001159767.1|refseq:NP_001159889.1|refseq:NP_054740.3|refseq:XP_005270484.1|refseq:XP_005270485.1|refseq:XP_006710394.1|refseq:XP_016855723.1|ensembl:ENSG00000117155(gene)|ensembl:ENST00000342203(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005912"(adherens junction)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031252"(cell leading edge)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0035735"(intraciliary transport involved in cilium assembly)|go:"GO:0036064"(ciliary basal body)|go:"GO:0060271"(cilium assembly)|go:"GO:2000145"(regulation of cell motility)|interpro:IPR021622|mint:Q9Y2D8	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:9OTjSNDfUXoxYLjdDlhobs3AKa8559292	rogid:E0VeMRF9SrpQKSJFP01XEbMjeF89606	intact-crc:5A36602C77F1EEF0|rigid:0S6RBVnmIXiApeCgZprKXozyULk	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P47041	uniprotkb:Q9Y2D8	intact:EBI-25889|uniprotkb:D6VWC4|ensemblfungi:YJL058C	intact:EBI-2212028|uniprotkb:B4DFE3|uniprotkb:J3KR02|uniprotkb:A8K8W0|uniprotkb:D3DT13|uniprotkb:Q6P2P8|uniprotkb:Q6ULS1|uniprotkb:Q7L168|uniprotkb:Q9UIX0|intact:EBI-10964529|ensembl:ENSP00000340279	psi-mi:bit61_yeast(display_long)|uniprotkb:YJL058C(locus name)|uniprotkb:J1141(orf name)|uniprotkb:61 kDa binding partner of TOR2 protein(gene name synonym)|uniprotkb:BIT61(gene name)|psi-mi:BIT61(display_short)	psi-mi:adip_human(display_long)|uniprotkb:SSX2IP(gene name)|psi-mi:SSX2IP(display_short)|uniprotkb:KIAA0923(gene name synonym)|uniprotkb:Afadin DIL domain-interacting protein(gene name synonym)|uniprotkb:SSX2-interacting protein(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11555120|imex:IM-24995-4351	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012477.1|sgd:S000003594|dip:DIP-1444N|reactome:R-SCE-1257604|reactome:R-SCE-389357|reactome:R-SCE-5218920|ensemblfungi:YJL058C(gene)|ensemblfungi:YJL058C_mRNA(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005737"(cytoplasm)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0031932"(TORC2 complex)|go:"GO:0038203"(TORC2 signaling)|go:"GO:0071944"(cell periphery)|interpro:IPR013745(HbrB-like)|reactome:R-SCE-6804757	refseq:XP_011538912.1|refseq:NP_001159765.1|refseq:NP_001159766.1|refseq:NP_001159767.1|refseq:NP_001159889.1|refseq:NP_054740.3|refseq:XP_005270484.1|refseq:XP_005270485.1|refseq:XP_006710394.1|refseq:XP_016855723.1|ensembl:ENSG00000117155(gene)|ensembl:ENST00000342203(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005912"(adherens junction)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031252"(cell leading edge)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0035735"(intraciliary transport involved in cilium assembly)|go:"GO:0036064"(ciliary basal body)|go:"GO:0060271"(cilium assembly)|go:"GO:2000145"(regulation of cell motility)|interpro:IPR021622|mint:Q9Y2D8	-	crc64:99F0F96840311F4B	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:H+zcKwbWL90wsmvD9TfWYmEbRwM559292	rogid:E0VeMRF9SrpQKSJFP01XEbMjeF89606	intact-crc:47E916FCBD6C01F8|rigid:GsJ5roI+fl2JX8Dy+oaZhNpR7Fc	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9Y2D8	uniprotkb:Q08204	intact:EBI-2212028|uniprotkb:B4DFE3|uniprotkb:J3KR02|uniprotkb:A8K8W0|uniprotkb:D3DT13|uniprotkb:Q6P2P8|uniprotkb:Q6ULS1|uniprotkb:Q7L168|uniprotkb:Q9UIX0|intact:EBI-10964529|ensembl:ENSP00000340279	intact:EBI-34125|uniprotkb:D6W231|ensemblfungi:YOL034W	psi-mi:adip_human(display_long)|uniprotkb:SSX2IP(gene name)|psi-mi:SSX2IP(display_short)|uniprotkb:KIAA0923(gene name synonym)|uniprotkb:Afadin DIL domain-interacting protein(gene name synonym)|uniprotkb:SSX2-interacting protein(gene name synonym)	psi-mi:smc5_yeast(display_long)|uniprotkb:SMC5(gene name)|psi-mi:SMC5(display_short)|uniprotkb:YOL034W(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11555124|imex:IM-24995-4352	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011538912.1|refseq:NP_001159765.1|refseq:NP_001159766.1|refseq:NP_001159767.1|refseq:NP_001159889.1|refseq:NP_054740.3|refseq:XP_005270484.1|refseq:XP_005270485.1|refseq:XP_006710394.1|refseq:XP_016855723.1|ensembl:ENSG00000117155(gene)|ensembl:ENST00000342203(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005912"(adherens junction)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031252"(cell leading edge)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0035735"(intraciliary transport involved in cilium assembly)|go:"GO:0036064"(ciliary basal body)|go:"GO:0060271"(cilium assembly)|go:"GO:2000145"(regulation of cell motility)|interpro:IPR021622|mint:Q9Y2D8	refseq:NP_014608.1|sgd:S000005394|mint:Q08204|dip:DIP-1979N|ensemblfungi:YOL034W(gene)|ensemblfungi:YOL034W_mRNA(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000725"(recombinational repair)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006281"(DNA repair)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0016925"(protein sumoylation)|go:"GO:0030915"(Smc5-Smc6 complex)|go:"GO:0051304"(chromosome separation)|go:"GO:0071139"(resolution of recombination intermediates)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR027131|interpro:IPR027417|rcsb pdb:3HTK|reactome:R-SCE-3108214	-	-	crc64:6752B96438CFB549	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:E0VeMRF9SrpQKSJFP01XEbMjeF89606	rogid:7EBoBNiTfotgfzhZ2+a+PcQTAqc559292	intact-crc:B1BA54F14B98DA33|rigid:wstO6eypXHeYmVjGP2B+Nh8mE2M	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q07379	uniprotkb:Q9Y2D8	intact:EBI-2342994|uniprotkb:D6VRT9|ensemblfungi:YDL057W	intact:EBI-2212028|uniprotkb:B4DFE3|uniprotkb:J3KR02|uniprotkb:A8K8W0|uniprotkb:D3DT13|uniprotkb:Q6P2P8|uniprotkb:Q6ULS1|uniprotkb:Q7L168|uniprotkb:Q9UIX0|intact:EBI-10964529|ensembl:ENSP00000340279	psi-mi:yd057_yeast(display_long)|uniprotkb:YDL057W(locus name)	psi-mi:adip_human(display_long)|uniprotkb:SSX2IP(gene name)|psi-mi:SSX2IP(display_short)|uniprotkb:KIAA0923(gene name synonym)|uniprotkb:Afadin DIL domain-interacting protein(gene name synonym)|uniprotkb:SSX2-interacting protein(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11555128|imex:IM-24995-4353	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002215|refseq:NP_010226.1|interpro:IPR022742|interpro:IPR029058|ensemblfungi:YDL057W(gene)|ensemblfungi:YDL057W_mRNA(transcript)|go:"GO:0016020"(membrane)|go:"GO:0016298"(lipase activity)	refseq:XP_011538912.1|refseq:NP_001159765.1|refseq:NP_001159766.1|refseq:NP_001159767.1|refseq:NP_001159889.1|refseq:NP_054740.3|refseq:XP_005270484.1|refseq:XP_005270485.1|refseq:XP_006710394.1|refseq:XP_016855723.1|ensembl:ENSG00000117155(gene)|ensembl:ENST00000342203(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005912"(adherens junction)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031252"(cell leading edge)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0035735"(intraciliary transport involved in cilium assembly)|go:"GO:0036064"(ciliary basal body)|go:"GO:0060271"(cilium assembly)|go:"GO:2000145"(regulation of cell motility)|interpro:IPR021622|mint:Q9Y2D8	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:U0Sf+t16Ti+vYEOEePrGjlqflhQ559292	rogid:E0VeMRF9SrpQKSJFP01XEbMjeF89606	intact-crc:32D463E7E6BA52F2|rigid:LpBusrQr3b/2e4C6qtgDdqgBuNo	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9Y2J4	uniprotkb:P33297	intact:EBI-746752|intact:EBI-28986657|ensembl:ENSP00000409999|uniprotkb:Q53EP1|uniprotkb:Q96F99|uniprotkb:Q9UKB4|uniprotkb:A8K6F1|uniprotkb:B7Z5Q1|uniprotkb:E9PHW3	intact:EBI-13920|uniprotkb:D6W2H6|ensemblfungi:YOR117W	psi-mi:amol2_human(display_long)|uniprotkb:Leman coiled-coil protein(gene name synonym)|uniprotkb:AMOTL2(gene name)|psi-mi:AMOTL2(display_short)|uniprotkb:KIAA0989(gene name synonym)	psi-mi:prs6a_yeast(display_long)|uniprotkb:RPT5(gene name)|psi-mi:RPT5(display_short)|uniprotkb:YTA1(gene name synonym)|uniprotkb:YOR117W(locus name)|uniprotkb:O3258(orf name)|uniprotkb:YOR3258W(orf name)|uniprotkb:Tat-binding protein homolog 1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11555152|imex:IM-24995-4359	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001265612.1|refseq:NP_001265614.1|ensembl:ENSG00000114019(gene)|refseq:XP_006713717.1|refseq:NP_057285.3|refseq:XP_011511183.1|ensembl:ENST00000422605(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0003365"(establishment of cell polarity involved in ameboidal cell migration)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0035329"(hippo signaling)|go:"GO:0055037"(recycling endosome)|interpro:IPR009114(Angiomotin)|interpro:IPR024646|mint:Q9Y2J4|reactome:R-HSA-2028269|refseq:XP_016862069.1|refseq:XP_016862070.1|refseq:XP_016862071.1|ensembl:ENST00000249883|ensembl:ENSP00000249883|ensembl:ENSP00000409999|ensembl:ENST00000513145|ensembl:ENSP00000425475|ensembl:ENST00000514516|ensembl:ENSP00000424765|dip:DIP-57510N	sgd:S000005643|rcsb pdb:3WHL|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MP9|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|rcsb pdb:3WHK|reactome:R-SCE-5689880|reactome:R-SCE-6798695|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|ensemblfungi:YOR117W(gene)|ensemblfungi:YOR117W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0070682"(proteasome regulatory particle assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035254|interpro:IPR041569|rcsb pdb:3JCO|rcsb pdb:3JCP|refseq:NP_014760.3|mint:P33297|dip:DIP-1590N	-	-	crc64:C215422033FCE830	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:SHtKAcLLnTpSSLwVE7yQ1WECoZk9606	rogid:jsQE3SjBA0ZZcysuLgFe/5M6pOc559292	intact-crc:E5F8CA7879727E21|rigid:trg69QZNG/6NNJMYouXfyimxBg0	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9Y2J4	uniprotkb:P53129	intact:EBI-746752|intact:EBI-28986657|ensembl:ENSP00000409999|uniprotkb:Q53EP1|uniprotkb:Q96F99|uniprotkb:Q9UKB4|uniprotkb:A8K6F1|uniprotkb:B7Z5Q1|uniprotkb:E9PHW3	intact:EBI-23945|uniprotkb:D6VU24|ensemblfungi:YGL124C	psi-mi:amol2_human(display_long)|uniprotkb:Leman coiled-coil protein(gene name synonym)|uniprotkb:AMOTL2(gene name)|psi-mi:AMOTL2(display_short)|uniprotkb:KIAA0989(gene name synonym)	psi-mi:mon1_yeast(display_long)|uniprotkb:YGL124C(locus name)|uniprotkb:G2889(orf name)|uniprotkb:MON1(gene name)|psi-mi:MON1(display_short)|uniprotkb:AUT12(gene name synonym)|uniprotkb:Monensin sensitivity protein 1(gene name synonym)|uniprotkb:Autophagy-related protein 12(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11555148|imex:IM-24995-4358	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001265612.1|refseq:NP_001265614.1|ensembl:ENSG00000114019(gene)|refseq:XP_006713717.1|refseq:NP_057285.3|refseq:XP_011511183.1|ensembl:ENST00000422605(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0003365"(establishment of cell polarity involved in ameboidal cell migration)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0035329"(hippo signaling)|go:"GO:0055037"(recycling endosome)|interpro:IPR009114(Angiomotin)|interpro:IPR024646|mint:Q9Y2J4|reactome:R-HSA-2028269|refseq:XP_016862069.1|refseq:XP_016862070.1|refseq:XP_016862071.1|ensembl:ENST00000249883|ensembl:ENSP00000249883|ensembl:ENSP00000409999|ensembl:ENST00000513145|ensembl:ENSP00000425475|ensembl:ENST00000514516|ensembl:ENSP00000424765|dip:DIP-57510N	refseq:NP_011391.2|sgd:S000003092|dip:DIP-5483N|mint:P53129|ensemblfungi:YGL124C(gene)|ensemblfungi:YGL124C_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006914"(autophagy)|go:"GO:0010314"(phosphatidylinositol-5-phosphate binding)|go:"GO:0016236"(macroautophagy)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0032585"(multivesicular body membrane)|go:"GO:0035658"(Mon1-Ccz1 complex)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044395"(protein targeting to vacuolar membrane)|go:"GO:0048278"(vesicle docking)|interpro:IPR004353(Protein of unknown function DUF254, SAND)|interpro:IPR043970|interpro:IPR043971|interpro:IPR043972|reactome:R-SCE-8876198	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:SHtKAcLLnTpSSLwVE7yQ1WECoZk9606	rogid:9tNVB/LFcvinM/mEzRj6ezSNCWo559292	intact-crc:D60DCAB9D500FFA0|rigid:4ZMhJLKK2G42jq8MacT3eZcTpvs	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P38340	uniprotkb:Q9Y2D8	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	intact:EBI-2212028|uniprotkb:B4DFE3|uniprotkb:J3KR02|uniprotkb:A8K8W0|uniprotkb:D3DT13|uniprotkb:Q6P2P8|uniprotkb:Q6ULS1|uniprotkb:Q7L168|uniprotkb:Q9UIX0|intact:EBI-10964529|ensembl:ENSP00000340279	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:adip_human(display_long)|uniprotkb:SSX2IP(gene name)|psi-mi:SSX2IP(display_short)|uniprotkb:KIAA0923(gene name synonym)|uniprotkb:Afadin DIL domain-interacting protein(gene name synonym)|uniprotkb:SSX2-interacting protein(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11555136|imex:IM-24995-4355	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F	refseq:XP_011538912.1|refseq:NP_001159765.1|refseq:NP_001159766.1|refseq:NP_001159767.1|refseq:NP_001159889.1|refseq:NP_054740.3|refseq:XP_005270484.1|refseq:XP_005270485.1|refseq:XP_006710394.1|refseq:XP_016855723.1|ensembl:ENSG00000117155(gene)|ensembl:ENST00000342203(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005912"(adherens junction)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031252"(cell leading edge)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0035735"(intraciliary transport involved in cilium assembly)|go:"GO:0036064"(ciliary basal body)|go:"GO:0060271"(cilium assembly)|go:"GO:2000145"(regulation of cell motility)|interpro:IPR021622|mint:Q9Y2D8	-	crc64:66699F37B0013088	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	rogid:E0VeMRF9SrpQKSJFP01XEbMjeF89606	intact-crc:3DFDB8B0986BAED0|rigid:6qAMXpSLuBuvHe7iirMVkcK0K8o	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P40454	uniprotkb:Q9Y2J4	intact:EBI-25278|uniprotkb:D6VVD4|ensemblfungi:YIL153W	intact:EBI-746752|intact:EBI-28986657|ensembl:ENSP00000409999|uniprotkb:Q53EP1|uniprotkb:Q96F99|uniprotkb:Q9UKB4|uniprotkb:A8K6F1|uniprotkb:B7Z5Q1|uniprotkb:E9PHW3	psi-mi:ptpa1_yeast(display_long)|uniprotkb:YIL153W(locus name)|uniprotkb:RRD1(gene name)|psi-mi:RRD1(display_short)|uniprotkb:NCS1(gene name synonym)|uniprotkb:YPA1(gene name synonym)|uniprotkb:Peptidyl-prolyl cis-trans isomerase PTPA-1(gene name synonym)|uniprotkb:Phosphotyrosyl phosphatase activator 1(gene name synonym)	psi-mi:amol2_human(display_long)|uniprotkb:Leman coiled-coil protein(gene name synonym)|uniprotkb:AMOTL2(gene name)|psi-mi:AMOTL2(display_short)|uniprotkb:KIAA0989(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11555140|imex:IM-24995-4356	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012113.1|sgd:S000001415|mint:P40454|dip:DIP-5663N|ensemblfungi:YIL153W(gene)|ensemblfungi:YIL153W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006914"(autophagy)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008160"(protein tyrosine phosphatase activator activity)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0043618"(regulation of transcription from RNA polymerase II promoter in response to stress)|interpro:IPR004327(Phosphotyrosyl phosphatase activator, PTPA)|interpro:IPR037218|interpro:IPR043170|rcsb pdb:2IXO|rcsb pdb:2IXP	refseq:NP_001265612.1|refseq:NP_001265614.1|ensembl:ENSG00000114019(gene)|refseq:XP_006713717.1|refseq:NP_057285.3|refseq:XP_011511183.1|ensembl:ENST00000422605(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0003365"(establishment of cell polarity involved in ameboidal cell migration)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0035329"(hippo signaling)|go:"GO:0055037"(recycling endosome)|interpro:IPR009114(Angiomotin)|interpro:IPR024646|mint:Q9Y2J4|reactome:R-HSA-2028269|refseq:XP_016862069.1|refseq:XP_016862070.1|refseq:XP_016862071.1|ensembl:ENST00000249883|ensembl:ENSP00000249883|ensembl:ENSP00000409999|ensembl:ENST00000513145|ensembl:ENSP00000425475|ensembl:ENST00000514516|ensembl:ENSP00000424765|dip:DIP-57510N	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:It2q8WlpmvLEZ1fqpRF5Fypw9Q4559292	rogid:SHtKAcLLnTpSSLwVE7yQ1WECoZk9606	intact-crc:03A47BC98B7F9CDE|rigid:rgEEfEcCVSwx03CIHbOgbMIWwIs	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9Y2J4	uniprotkb:Q07732	intact:EBI-746752|intact:EBI-28986657|ensembl:ENSP00000409999|uniprotkb:Q53EP1|uniprotkb:Q96F99|uniprotkb:Q9UKB4|uniprotkb:A8K6F1|uniprotkb:B7Z5Q1|uniprotkb:E9PHW3	intact:EBI-33406|ensemblfungi:YDL239C|uniprotkb:D6VRB7	psi-mi:amol2_human(display_long)|uniprotkb:Leman coiled-coil protein(gene name synonym)|uniprotkb:AMOTL2(gene name)|psi-mi:AMOTL2(display_short)|uniprotkb:KIAA0989(gene name synonym)	psi-mi:ady3_yeast(display_long)|uniprotkb:YDL239C(locus name)|uniprotkb:ADY3(gene name)|psi-mi:ADY3(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11555144|imex:IM-24995-4357	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001265612.1|refseq:NP_001265614.1|ensembl:ENSG00000114019(gene)|refseq:XP_006713717.1|refseq:NP_057285.3|refseq:XP_011511183.1|ensembl:ENST00000422605(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0003365"(establishment of cell polarity involved in ameboidal cell migration)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0035329"(hippo signaling)|go:"GO:0055037"(recycling endosome)|interpro:IPR009114(Angiomotin)|interpro:IPR024646|mint:Q9Y2J4|reactome:R-HSA-2028269|refseq:XP_016862069.1|refseq:XP_016862070.1|refseq:XP_016862071.1|ensembl:ENST00000249883|ensembl:ENSP00000249883|ensembl:ENSP00000409999|ensembl:ENST00000513145|ensembl:ENSP00000425475|ensembl:ENST00000514516|ensembl:ENSP00000424765|dip:DIP-57510N	refseq:NP_010042.2|sgd:S000002398|ensemblfungi:YDL239C(gene)|ensemblfungi:YDL239C_mRNA(transcript)|go:"GO:0000001"(mitochondrion inheritance)|go:"GO:0005628"(prospore membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0030435"(sporulation resulting in formation of a cellular spore)|go:"GO:0030476"(ascospore wall assembly)|go:"GO:0032120"(ascospore-type prospore membrane formation)|go:"GO:0051301"(cell division)|go:"GO:0070056"(prospore membrane leading edge)|interpro:IPR021750|mint:Q07732|dip:DIP-1811N	-	-	crc64:46F17474F30FD3D9	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:SHtKAcLLnTpSSLwVE7yQ1WECoZk9606	rogid:Cmac2NLDdbBzVKnJfFricfeeX24559292	intact-crc:E56D158DC809E7B5|rigid:O4SyFP0fLm1NYk8An6KJOIssr18	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P40482	uniprotkb:Q9Y2W2	intact:EBI-16592|ensemblfungi:YIL109C|uniprotkb:D6VVH8	intact:EBI-714455|ensembl:ENSP00000261167|uniprotkb:Q96AY8	psi-mi:sec24_yeast(display_long)|uniprotkb:SEC24(gene name)|psi-mi:SEC24(display_short)|uniprotkb:Abnormal nuclear morphology 1(gene name synonym)|uniprotkb:ANU1(gene name synonym)|uniprotkb:YIL109C(locus name)	psi-mi:wbp11_human(display_long)|uniprotkb:SH3 domain-binding protein SNP70(gene name synonym)|uniprotkb:Npw38-binding protein(gene name synonym)|uniprotkb:WBP11(gene name)|psi-mi:WBP11(display_short)|uniprotkb:NPWBP(gene name synonym)|uniprotkb:SNP70(gene name synonym)|uniprotkb:SIPP1(gene name synonym)|uniprotkb:Splicing factor that interacts with PQBP-1 and PP1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11555172|imex:IM-24995-4364	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012157.3|ensemblfungi:YIL109C(gene)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016236"(macroautophagy)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0070971"(endoplasmic reticulum exit site)|ensemblfungi:YIL109C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0090110"(COPII-coated vesicle cargo loading)|interpro:IPR006895(Zinc finger, Sec23/Sec24-type)|interpro:IPR006896(Sec23/Sec24 trunk region)|interpro:IPR006900(Sec23/Sec24 helical region)|interpro:IPR007123(Gelsolin region)|interpro:IPR012990(Sec23/Sec24 beta-sandwich)|interpro:IPR029006|interpro:IPR036174|interpro:IPR036175|interpro:IPR036180|go:"GO:0000149"(SNARE binding)|go:"GO:0000329"(fungal-type vacuole membrane)|interpro:IPR036465|interpro:IPR041742|rcsb pdb:1M2V|rcsb pdb:1PCX|rcsb pdb:1PD0|rcsb pdb:1PD1|rcsb pdb:4BZI|rcsb pdb:6GNI|rcsb pdb:6ZGA|reactome:R-SCE-204005|reactome:R-SCE-5694530|reactome:R-SCE-983170|go:"GO:0005048"(signal sequence binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|sgd:S000001371|dip:DIP-2233N|mint:P40482	rcsb pdb:7ABG|reactome:R-HSA-72163|ensembl:ENSG00000084463(gene)|ensembl:ENST00000261167(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045292"(mRNA cis splicing, via spliceosome)|go:"GO:0050699"(WW domain binding)|interpro:IPR019007|mint:Q9Y2W2|rcsb pdb:7ABF|refseq:NP_057396.1	-	crc64:35E2BDD24CC75899	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:e7ekVFzZJMZvfRUZ9Q2jDQ/hvs0559292	rogid:qE03bpSsQiJouJbn6ISt8DnD/pA9606	intact-crc:05BACACF58DE9F04|rigid:dzrYIXOOYHA8fIJECJRnipXxixE	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P53829	uniprotkb:Q9Y2J4	intact:EBI-28306|uniprotkb:D6W0Q5|ensemblfungi:YNL288W	intact:EBI-746752|intact:EBI-28986657|ensembl:ENSP00000409999|uniprotkb:Q53EP1|uniprotkb:Q96F99|uniprotkb:Q9UKB4|uniprotkb:A8K6F1|uniprotkb:B7Z5Q1|uniprotkb:E9PHW3	psi-mi:caf40_yeast(display_long)|uniprotkb:YNL288W(locus name)|uniprotkb:N0540(orf name)|uniprotkb:40 kDa CCR4-associated factor(gene name synonym)|uniprotkb:CAF40(gene name)|psi-mi:CAF40(display_short)	psi-mi:amol2_human(display_long)|uniprotkb:Leman coiled-coil protein(gene name synonym)|uniprotkb:AMOTL2(gene name)|psi-mi:AMOTL2(display_short)|uniprotkb:KIAA0989(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11555168|imex:IM-24995-4363	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014111.1|sgd:S000005232|dip:DIP-1995N|mint:P53829|ensemblfungi:YNL288W(gene)|ensemblfungi:YNL288W_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR007216(Cell differentiation, Rcd1-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:4CV5	refseq:NP_001265612.1|refseq:NP_001265614.1|ensembl:ENSG00000114019(gene)|refseq:XP_006713717.1|refseq:NP_057285.3|refseq:XP_011511183.1|ensembl:ENST00000422605(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0003365"(establishment of cell polarity involved in ameboidal cell migration)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0035329"(hippo signaling)|go:"GO:0055037"(recycling endosome)|interpro:IPR009114(Angiomotin)|interpro:IPR024646|mint:Q9Y2J4|reactome:R-HSA-2028269|refseq:XP_016862069.1|refseq:XP_016862070.1|refseq:XP_016862071.1|ensembl:ENST00000249883|ensembl:ENSP00000249883|ensembl:ENSP00000409999|ensembl:ENST00000513145|ensembl:ENSP00000425475|ensembl:ENST00000514516|ensembl:ENSP00000424765|dip:DIP-57510N	-	crc64:F3DBABE6AD3C7F3C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:etuSSgFGQOcgxPDexEXUqQg6H5s559292	rogid:SHtKAcLLnTpSSLwVE7yQ1WECoZk9606	intact-crc:A01EFC5F91FD3F6E|rigid:wL97b/N7Zx3p3qCYb4ZACTiLgkw	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9Y2J4	uniprotkb:P32458	intact:EBI-746752|intact:EBI-28986657|ensembl:ENSP00000409999|uniprotkb:Q53EP1|uniprotkb:Q96F99|uniprotkb:Q9UKB4|uniprotkb:A8K6F1|uniprotkb:B7Z5Q1|uniprotkb:E9PHW3	intact:EBI-4178|uniprotkb:D6VWP6|ensemblfungi:YJR076C	psi-mi:amol2_human(display_long)|uniprotkb:Leman coiled-coil protein(gene name synonym)|uniprotkb:AMOTL2(gene name)|psi-mi:AMOTL2(display_short)|uniprotkb:KIAA0989(gene name synonym)	psi-mi:cdc11_yeast(display_long)|uniprotkb:CDC11(gene name)|psi-mi:CDC11(display_short)|uniprotkb:PSL9(gene name synonym)|uniprotkb:YJR076C(locus name)|uniprotkb:J1833(orf name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11555156|imex:IM-24995-4360	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001265612.1|refseq:NP_001265614.1|ensembl:ENSG00000114019(gene)|refseq:XP_006713717.1|refseq:NP_057285.3|refseq:XP_011511183.1|ensembl:ENST00000422605(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0003365"(establishment of cell polarity involved in ameboidal cell migration)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0035329"(hippo signaling)|go:"GO:0055037"(recycling endosome)|interpro:IPR009114(Angiomotin)|interpro:IPR024646|mint:Q9Y2J4|reactome:R-HSA-2028269|refseq:XP_016862069.1|refseq:XP_016862070.1|refseq:XP_016862071.1|ensembl:ENST00000249883|ensembl:ENSP00000249883|ensembl:ENSP00000409999|ensembl:ENST00000513145|ensembl:ENSP00000425475|ensembl:ENST00000514516|ensembl:ENSP00000424765|dip:DIP-57510N	refseq:NP_012610.1|sgd:S000003837|dip:DIP-1656N|mint:P32458|ensemblfungi:YJR076C(gene)|ensemblfungi:YJR076C_mRNA(transcript)|go:"GO:0000144"(cellular bud neck septin ring)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000915"(actomyosin contractile ring assembly)|go:"GO:0000917"(division septum assembly)|go:"GO:0001400"(mating projection base)|go:"GO:0003924"(GTPase activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005619"(ascospore wall)|go:"GO:0005628"(prospore membrane)|go:"GO:0005876"(spindle microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0005935"(cellular bud neck)|go:"GO:0005940"(septin ring)|go:"GO:0010314"(phosphatidylinositol-5-phosphate binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030011"(maintenance of cell polarity)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0032160"(septin filament array)|go:"GO:0032186"(cellular bud neck septin ring organization)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042802"(identical protein binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0072687"(meiotic spindle)|go:"GO:0097271"(protein localization to bud neck)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|rcsb pdb:5AR1	-	-	crc64:5CFFD4CD1F6C57D4	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:SHtKAcLLnTpSSLwVE7yQ1WECoZk9606	rogid:KRcNMx6EOTmvHb+6u15UrVoyb3s559292	intact-crc:3BDFE0023673EEFD|rigid:jvPfSTR3KoFtSOGZW0zusIT43Pw	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q07379	uniprotkb:Q9Y2J4	intact:EBI-2342994|uniprotkb:D6VRT9|ensemblfungi:YDL057W	intact:EBI-746752|intact:EBI-28986657|ensembl:ENSP00000409999|uniprotkb:Q53EP1|uniprotkb:Q96F99|uniprotkb:Q9UKB4|uniprotkb:A8K6F1|uniprotkb:B7Z5Q1|uniprotkb:E9PHW3	psi-mi:yd057_yeast(display_long)|uniprotkb:YDL057W(locus name)	psi-mi:amol2_human(display_long)|uniprotkb:Leman coiled-coil protein(gene name synonym)|uniprotkb:AMOTL2(gene name)|psi-mi:AMOTL2(display_short)|uniprotkb:KIAA0989(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11555160|imex:IM-24995-4361	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002215|refseq:NP_010226.1|interpro:IPR022742|interpro:IPR029058|ensemblfungi:YDL057W(gene)|ensemblfungi:YDL057W_mRNA(transcript)|go:"GO:0016020"(membrane)|go:"GO:0016298"(lipase activity)	refseq:NP_001265612.1|refseq:NP_001265614.1|ensembl:ENSG00000114019(gene)|refseq:XP_006713717.1|refseq:NP_057285.3|refseq:XP_011511183.1|ensembl:ENST00000422605(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0003365"(establishment of cell polarity involved in ameboidal cell migration)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0035329"(hippo signaling)|go:"GO:0055037"(recycling endosome)|interpro:IPR009114(Angiomotin)|interpro:IPR024646|mint:Q9Y2J4|reactome:R-HSA-2028269|refseq:XP_016862069.1|refseq:XP_016862070.1|refseq:XP_016862071.1|ensembl:ENST00000249883|ensembl:ENSP00000249883|ensembl:ENSP00000409999|ensembl:ENST00000513145|ensembl:ENSP00000425475|ensembl:ENST00000514516|ensembl:ENSP00000424765|dip:DIP-57510N	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:U0Sf+t16Ti+vYEOEePrGjlqflhQ559292	rogid:SHtKAcLLnTpSSLwVE7yQ1WECoZk9606	intact-crc:352971468E67D04D|rigid:lshhUmMY13Dj00iSsAILwXja8W8	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9Y2J4	uniprotkb:Q99344	intact:EBI-746752|intact:EBI-28986657|ensembl:ENSP00000409999|uniprotkb:Q53EP1|uniprotkb:Q96F99|uniprotkb:Q9UKB4|uniprotkb:A8K6F1|uniprotkb:B7Z5Q1|uniprotkb:E9PHW3	intact:EBI-37997|uniprotkb:D6W470|uniprotkb:E9P8X1|ensemblfungi:YPR066W	psi-mi:amol2_human(display_long)|uniprotkb:Leman coiled-coil protein(gene name synonym)|uniprotkb:AMOTL2(gene name)|psi-mi:AMOTL2(display_short)|uniprotkb:KIAA0989(gene name synonym)	psi-mi:uba3_yeast(display_long)|uniprotkb:Ubiquitin-activating enzyme E1 3(gene name synonym)|uniprotkb:RUB1-activating enzyme E1(gene name synonym)|uniprotkb:Ubiquitin-like protein-activating enzyme(gene name synonym)|uniprotkb:UBA3(gene name)|psi-mi:UBA3(display_short)|uniprotkb:YPR066W(locus name)|uniprotkb:YP9499.21(orf name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11555164|imex:IM-24995-4362	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001265612.1|refseq:NP_001265614.1|ensembl:ENSG00000114019(gene)|refseq:XP_006713717.1|refseq:NP_057285.3|refseq:XP_011511183.1|ensembl:ENST00000422605(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0003365"(establishment of cell polarity involved in ameboidal cell migration)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0035329"(hippo signaling)|go:"GO:0055037"(recycling endosome)|interpro:IPR009114(Angiomotin)|interpro:IPR024646|mint:Q9Y2J4|reactome:R-HSA-2028269|refseq:XP_016862069.1|refseq:XP_016862070.1|refseq:XP_016862071.1|ensembl:ENST00000249883|ensembl:ENSP00000249883|ensembl:ENSP00000409999|ensembl:ENST00000513145|ensembl:ENSP00000425475|ensembl:ENST00000514516|ensembl:ENSP00000424765|dip:DIP-57510N	refseq:NP_015391.1|sgd:S000006270|ensemblfungi:YPR066W(gene)|ensemblfungi:YPR066W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0019781"(NEDD8 activating enzyme activity)|go:"GO:0032446"(protein modification by small protein conjugation)|go:"GO:0045116"(protein neddylation)|interpro:IPR000594(UBA/THIF-type NAD/FAD binding fold)|interpro:IPR023318|interpro:IPR030468|interpro:IPR033127|dip:DIP-1719N|interpro:IPR035985|reactome:R-SCE-983168	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:SHtKAcLLnTpSSLwVE7yQ1WECoZk9606	rogid:W38WpbRWXZjHVLC7ECqtRkmDBpI559292	intact-crc:8CE5668CC3091D92|rigid:W4gM1LLSUF8w2gQk797gpk3Abkc	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9Y3A3	uniprotkb:P40454	intact:EBI-713935|uniprotkb:Q7Z4Y6|uniprotkb:Q9H2P3|uniprotkb:Q53SE0|uniprotkb:Q9H5J1|uniprotkb:Q9Y4T8|ensembl:ENSP00000315702|uniprotkb:B4DML0	intact:EBI-25278|uniprotkb:D6VVD4|ensemblfungi:YIL153W	psi-mi:phocn_human(display_long)|uniprotkb:MOB4(gene name)|psi-mi:MOB4(display_short)|uniprotkb:2C4D(gene name synonym)|uniprotkb:Class II mMOB1(gene name synonym)|uniprotkb:MOB3(gene name synonym)|uniprotkb:MOBKL3(gene name synonym)|uniprotkb:Mob1 homolog 3(gene name synonym)|uniprotkb:Mps one binder kinase activator-like 3(gene name synonym)|uniprotkb:PHOCN(gene name synonym)|uniprotkb:PREI3(gene name synonym)|uniprotkb:Preimplantation protein 3(gene name synonym)|uniprotkb:CGI-95(orf name)	psi-mi:ptpa1_yeast(display_long)|uniprotkb:YIL153W(locus name)|uniprotkb:RRD1(gene name)|psi-mi:RRD1(display_short)|uniprotkb:NCS1(gene name synonym)|uniprotkb:YPA1(gene name synonym)|uniprotkb:Peptidyl-prolyl cis-trans isomerase PTPA-1(gene name synonym)|uniprotkb:Phosphotyrosyl phosphatase activator 1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11555200|imex:IM-24995-4371	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000115540(gene)|ensembl:ENST00000323303(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR005301(Mob1/phocein)|interpro:IPR036703|mint:Q9Y3A3|rcsb pdb:5YF4|rcsb pdb:7K36|refseq:NP_001094289.1|refseq:NP_001191023.1|refseq:NP_056202.2|refseq:NP_955776.1	refseq:NP_012113.1|sgd:S000001415|mint:P40454|dip:DIP-5663N|ensemblfungi:YIL153W(gene)|ensemblfungi:YIL153W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006914"(autophagy)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008160"(protein tyrosine phosphatase activator activity)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0043618"(regulation of transcription from RNA polymerase II promoter in response to stress)|interpro:IPR004327(Phosphotyrosyl phosphatase activator, PTPA)|interpro:IPR037218|interpro:IPR043170|rcsb pdb:2IXO|rcsb pdb:2IXP	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:ihsb3qrdGqwKdh6ZhHlJlwBGJbc9606	rogid:It2q8WlpmvLEZ1fqpRF5Fypw9Q4559292	intact-crc:8C35E55F8873A403|rigid:Cbagm22pvT6WWsyDkpFx9yTzWz4	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9Y371	uniprotkb:P38340	intact:EBI-2623095|uniprotkb:Q9H3Z0|uniprotkb:Q9NYA9|uniprotkb:Q9NR47|uniprotkb:Q5H8U5|ensembl:ENSP00000473267|uniprotkb:B4E182	intact:EBI-21116|uniprotkb:D6VQQ8|ensemblfungi:YBR261C	psi-mi:shlb1_human(display_long)|uniprotkb:KIAA0491(gene name synonym)|uniprotkb:Bax-interacting factor 1(gene name synonym)|uniprotkb:SH3 domain-containing GRB2-like protein B1(gene name synonym)|uniprotkb:CGI-61(orf name)|uniprotkb:SH3GLB1(gene name)|psi-mi:SH3GLB1(display_short)	psi-mi:ntm1_yeast(display_long)|uniprotkb:YBR261C(locus name)|uniprotkb:YBR1729(orf name)|uniprotkb:TAE1(gene name)|psi-mi:TAE1(display_short)|uniprotkb:NTM1(gene name synonym)|uniprotkb:Translation associated element 1(gene name synonym)|uniprotkb:X-Pro-Lys N-terminal protein methyltransferase 1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11555196|imex:IM-24995-4370	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001193580.1|refseq:NP_001193581.1|refseq:NP_057093.1|go:"GO:0030496"(midbody)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032801"(receptor catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0048102"(autophagic cell death)|go:"GO:0090148"(membrane fission)|go:"GO:1903527"(positive regulation of membrane tubulation)|go:"GO:1903778"(protein localization to vacuolar membrane)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|go:"GO:2000786"(positive regulation of autophagosome assembly)|interpro:IPR001452(Src homology-3)|interpro:IPR004148(BAR)|interpro:IPR027267|interpro:IPR028503|interpro:IPR035695|interpro:IPR036028|mint:Q9Y371|rcsb pdb:6UP6|rcsb pdb:6UPN|ensembl:ENSG00000097033(gene)|ensembl:ENST00000370558(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0006915"(apoptotic process)|go:"GO:0008289"(lipid binding)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016241"(regulation of macroautophagy)|refseq:NP_001193582.1|dip:DIP-41970N	refseq:NP_009820.1|sgd:S000000465|dip:DIP-4951N|ensemblfungi:YBR261C(gene)|ensemblfungi:YBR261C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006480"(N-terminal protein amino acid methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0018016"(N-terminal peptidyl-proline dimethylation)|go:"GO:0071885"(N-terminal protein N-methyltransferase activity)|interpro:IPR008576(Protein of unknown function DUF858, methyltransferase-like)|interpro:IPR029063|rcsb pdb:7D8D|rcsb pdb:7D8F	-	-	crc64:66699F37B0013088	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:HSs455W45ciZL56fJSPOIvfhUIw9606	rogid:y1CNvIFYUIwljWylqqxSrg74BxA559292	intact-crc:750A60F69AAC1AAA|rigid:y/esqv3+RMBW2Zk3eJGXwnsBAZ0	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P53218	uniprotkb:Q9Y371	intact:EBI-13662|uniprotkb:D6VUG5|ensemblfungi:YGR030C	intact:EBI-2623095|uniprotkb:Q9H3Z0|uniprotkb:Q9NYA9|uniprotkb:Q9NR47|uniprotkb:Q5H8U5|ensembl:ENSP00000473267|uniprotkb:B4E182	psi-mi:pop6_yeast(display_long)|uniprotkb:POP6(gene name)|psi-mi:POP6(display_short)|uniprotkb:RNA-processing protein POP6(gene name synonym)|uniprotkb:RNases P/MRP 18.2 kDa subunit(gene name synonym)|uniprotkb:YGR030C(locus name)	psi-mi:shlb1_human(display_long)|uniprotkb:KIAA0491(gene name synonym)|uniprotkb:Bax-interacting factor 1(gene name synonym)|uniprotkb:SH3 domain-containing GRB2-like protein B1(gene name synonym)|uniprotkb:CGI-61(orf name)|uniprotkb:SH3GLB1(gene name)|psi-mi:SH3GLB1(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11555192|imex:IM-24995-4369	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011544.1|sgd:S000003262|ensemblfungi:YGR030C(gene)|ensemblfungi:YGR030C_mRNA(transcript)|go:"GO:0000172"(ribonuclease MRP complex)|go:"GO:0000294"(nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay)|go:"GO:0003723"(RNA binding)|go:"GO:0004526"(ribonuclease P activity)|go:"GO:0005634"(nucleus)|go:"GO:0005655"(nucleolar ribonuclease P complex)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0008033"(tRNA processing)|go:"GO:0034965"(intronic box C/D RNA processing)|go:"GO:0042134"(rRNA primary transcript binding)|interpro:IPR002775(Alba, DNA/RNA-binding protein)|rcsb pdb:3IAB|rcsb pdb:6AGB|rcsb pdb:6AH3|rcsb pdb:6W6V|rcsb pdb:7C79|rcsb pdb:7C7A|mint:P53218|dip:DIP-6775N	refseq:NP_001193580.1|refseq:NP_001193581.1|refseq:NP_057093.1|go:"GO:0030496"(midbody)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032801"(receptor catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0048102"(autophagic cell death)|go:"GO:0090148"(membrane fission)|go:"GO:1903527"(positive regulation of membrane tubulation)|go:"GO:1903778"(protein localization to vacuolar membrane)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|go:"GO:2000786"(positive regulation of autophagosome assembly)|interpro:IPR001452(Src homology-3)|interpro:IPR004148(BAR)|interpro:IPR027267|interpro:IPR028503|interpro:IPR035695|interpro:IPR036028|mint:Q9Y371|rcsb pdb:6UP6|rcsb pdb:6UPN|ensembl:ENSG00000097033(gene)|ensembl:ENST00000370558(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0006915"(apoptotic process)|go:"GO:0008289"(lipid binding)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016241"(regulation of macroautophagy)|refseq:NP_001193582.1|dip:DIP-41970N	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:ynYc14nNfgwjbvWl8qgK5nKGOOo559292	rogid:HSs455W45ciZL56fJSPOIvfhUIw9606	intact-crc:A194E581D6014992|rigid:eV2qszuzE22qQIQPSb168a36WRY	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9Y2W2	uniprotkb:P39682	intact:EBI-714455|ensembl:ENSP00000261167|uniprotkb:Q96AY8	intact:EBI-612|uniprotkb:D6VZC9|uniprotkb:E9P8Z1|ensemblfungi:YML046W	psi-mi:wbp11_human(display_long)|uniprotkb:SH3 domain-binding protein SNP70(gene name synonym)|uniprotkb:Npw38-binding protein(gene name synonym)|uniprotkb:WBP11(gene name)|psi-mi:WBP11(display_short)|uniprotkb:NPWBP(gene name synonym)|uniprotkb:SNP70(gene name synonym)|uniprotkb:SIPP1(gene name synonym)|uniprotkb:Splicing factor that interacts with PQBP-1 and PP1(gene name synonym)	psi-mi:prp39_yeast(display_long)|uniprotkb:YM9827.06(orf name)|uniprotkb:YML046W(locus name)|uniprotkb:PRP39(gene name)|psi-mi:PRP39(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11555176|imex:IM-24995-4365	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:7ABG|reactome:R-HSA-72163|ensembl:ENSG00000084463(gene)|ensembl:ENST00000261167(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045292"(mRNA cis splicing, via spliceosome)|go:"GO:0050699"(WW domain binding)|interpro:IPR019007|mint:Q9Y2W2|rcsb pdb:7ABF|refseq:NP_057396.1	refseq:NP_013667.1|sgd:S000004509|dip:DIP-812N|mint:P39682|ensemblfungi:YML046W(gene)|ensemblfungi:YML046W_mRNA(transcript)|go:"GO:0000243"(commitment complex)|go:"GO:0000395"(mRNA 5'-splice site recognition)|go:"GO:0005685"(U1 snRNP)|go:"GO:0071004"(U2-type prespliceosome)|interpro:IPR003107(RNA-processing protein, HAT helix)|interpro:IPR011990(Tetratricopeptide-like helical)|rcsb pdb:5ZWN|rcsb pdb:6G90|rcsb pdb:6N7P|rcsb pdb:6N7R|rcsb pdb:6N7X	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:qE03bpSsQiJouJbn6ISt8DnD/pA9606	rogid:urVLzQFKnYT1bYOs3yRd9dd7lMk559292	intact-crc:D327114D1A333FAB|rigid:oltImCl3zp8ZWC8W1/c6MUH6kTI	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P23285	uniprotkb:Q9Y2W7	intact:EBI-5448|uniprotkb:D3DL06|ensemblfungi:YHR057C	intact:EBI-751501|uniprotkb:Q53TJ5|uniprotkb:Q96T40|uniprotkb:Q9UJ84|uniprotkb:Q9UJ85|uniprotkb:Q3YAC3|uniprotkb:Q3YAC4|uniprotkb:H7BY46|ensembl:ENSP00000295225	psi-mi:cypb_yeast(display_long)|uniprotkb:CYP2(gene name synonym)|uniprotkb:YHR057C(locus name)|uniprotkb:CPR2(gene name)|psi-mi:CPR2(display_short)|uniprotkb:CRG(gene name synonym)|uniprotkb:SCC2(gene name synonym)|uniprotkb:Cyclophilin B(gene name synonym)|uniprotkb:Cyclophilin-related protein(gene name synonym)|uniprotkb:Rotamase B(gene name synonym)	psi-mi:csen_human(display_long)|uniprotkb:Kv channel-interacting protein 3(gene name synonym)|uniprotkb:A-type potassium channel modulatory protein 3(gene name synonym)|uniprotkb:DRE-antagonist modulator(gene name synonym)|uniprotkb:KCNIP3(gene name)|psi-mi:KCNIP3(display_short)|uniprotkb:DREAM(gene name synonym)|uniprotkb:KCHIP3(gene name synonym)|uniprotkb:CSEN(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11555184|imex:IM-24995-4367	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011924.1|sgd:S000001099|dip:DIP-1280N|ensemblfungi:YHR057C(gene)|ensemblfungi:YHR057C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006457"(protein folding)|go:"GO:0016018"(cyclosporin A binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|interpro:IPR020892|interpro:IPR024936|interpro:IPR029000	refseq:NP_001030086.1|refseq:NP_038462.1|ensembl:ENSG00000115041(gene)|ensembl:ENST00000295225(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005244"(voltage-gated ion channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0030425"(dendrite)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0043679"(axon terminus)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:1901379"(regulation of potassium ion transmembrane transport)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR028846|rcsb pdb:2E6W|reactome:R-HSA-5576894	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:jKSwBj1KpYZTRNaWOrKxCwC0rAY559292	rogid:Mqp4XdEur4uc6jY9dGsn8CHLE4w9606	intact-crc:47639A90DD24EF0C|rigid:aQbFCfB0uPIea3j+XVISVUl8XIw	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9Y2W2	uniprotkb:P20081	intact:EBI-714455|ensembl:ENSP00000261167|uniprotkb:Q96AY8	intact:EBI-6961|uniprotkb:D6W147|ensemblfungi:YNL135C	psi-mi:wbp11_human(display_long)|uniprotkb:SH3 domain-binding protein SNP70(gene name synonym)|uniprotkb:Npw38-binding protein(gene name synonym)|uniprotkb:WBP11(gene name)|psi-mi:WBP11(display_short)|uniprotkb:NPWBP(gene name synonym)|uniprotkb:SNP70(gene name synonym)|uniprotkb:SIPP1(gene name synonym)|uniprotkb:Splicing factor that interacts with PQBP-1 and PP1(gene name synonym)	psi-mi:fkbp_yeast(display_long)|uniprotkb:RBP1(gene name synonym)|uniprotkb:N1213(orf name)|uniprotkb:N1845(orf name)|uniprotkb:YNL135C(locus name)|uniprotkb:FPR1(gene name)|psi-mi:FPR1(display_short)|uniprotkb:FKB1(gene name synonym)|uniprotkb:Peptidyl-prolyl cis-trans isomerase(gene name synonym)|uniprotkb:Rapamycin-binding protein(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11555180|imex:IM-24995-4366	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:7ABG|reactome:R-HSA-72163|ensembl:ENSG00000084463(gene)|ensembl:ENST00000261167(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045292"(mRNA cis splicing, via spliceosome)|go:"GO:0050699"(WW domain binding)|interpro:IPR019007|mint:Q9Y2W2|rcsb pdb:7ABF|refseq:NP_057396.1	refseq:NP_014264.1|sgd:S000005079|dip:DIP-1263N|mint:P20081|ensemblfungi:YNL135C(gene)|ensemblfungi:YNL135C_mRNA(transcript)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005527"(macrolide binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006325"(chromatin organization)|go:"GO:0006457"(protein folding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:1901710"(regulation of homoserine biosynthetic process)|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)|rcsb pdb:1YAT	-	-	crc64:65C134830D300C06	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:qE03bpSsQiJouJbn6ISt8DnD/pA9606	rogid:8afvGSk+mPghtqkVoWd2rHJXXhQ559292	intact-crc:F22D0DE148E55BA0|rigid:Yp9hgufBgRCAaH1qCnbXNzwHKb0	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P35176	uniprotkb:Q9Y2W7	intact:EBI-5458|uniprotkb:D6VST3|ensemblfungi:YDR304C	intact:EBI-751501|uniprotkb:Q53TJ5|uniprotkb:Q96T40|uniprotkb:Q9UJ84|uniprotkb:Q9UJ85|uniprotkb:Q3YAC3|uniprotkb:Q3YAC4|uniprotkb:H7BY46|ensembl:ENSP00000295225	psi-mi:cypd_yeast(display_long)|uniprotkb:CPR5(gene name)|psi-mi:CPR5(display_short)|uniprotkb:YDR304C(locus name)|uniprotkb:D9740.14(orf name)|uniprotkb:CYP5(gene name synonym)|uniprotkb:CYPD(gene name synonym)|uniprotkb:Cyclophilin D(gene name synonym)|uniprotkb:Rotamase D(gene name synonym)	psi-mi:csen_human(display_long)|uniprotkb:Kv channel-interacting protein 3(gene name synonym)|uniprotkb:A-type potassium channel modulatory protein 3(gene name synonym)|uniprotkb:DRE-antagonist modulator(gene name synonym)|uniprotkb:KCNIP3(gene name)|psi-mi:KCNIP3(display_short)|uniprotkb:DREAM(gene name synonym)|uniprotkb:KCHIP3(gene name synonym)|uniprotkb:CSEN(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11555188|imex:IM-24995-4368	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002712|refseq:NP_010590.3|dip:DIP-5222N|mint:P35176|ensemblfungi:YDR304C(gene)|ensemblfungi:YDR304C_mRNA(transcript)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006457"(protein folding)|go:"GO:0016018"(cyclosporin A binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|interpro:IPR020892|interpro:IPR029000	refseq:NP_001030086.1|refseq:NP_038462.1|ensembl:ENSG00000115041(gene)|ensembl:ENST00000295225(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005244"(voltage-gated ion channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0030425"(dendrite)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0043679"(axon terminus)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:1901379"(regulation of potassium ion transmembrane transport)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR028846|rcsb pdb:2E6W|reactome:R-HSA-5576894	-	crc64:F4861424C8443B58	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:aCn3loYoSVWfy5Tb5i+MsOHcUEo559292	rogid:Mqp4XdEur4uc6jY9dGsn8CHLE4w9606	intact-crc:0F38E9E7B465964D|rigid:Rgk6L/T/O7f9603f2m87crcxBaE	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9Y3Q8	uniprotkb:P25372	intact:EBI-739485|uniprotkb:A8MWR6|ensembl:ENSP00000300181|uniprotkb:A4D2C3|uniprotkb:D6W5V9	intact:EBI-19616|uniprotkb:D6VR84|ensemblfungi:YCR083W	psi-mi:t22d4_human(display_long)|uniprotkb:TSC22D4(gene name)|psi-mi:TSC22D4(display_short)|uniprotkb:TILZ2(gene name synonym)|uniprotkb:TSC22-related-inducible leucine zipper protein 2(gene name synonym)|uniprotkb:Tsc-22-like protein THG-1(gene name synonym)|uniprotkb:THG1(gene name synonym)	psi-mi:trx3_yeast(display_long)|uniprotkb:TRX3(gene name)|psi-mi:TRX3(display_short)|uniprotkb:YCR83W(orf name)|uniprotkb:YCR083W(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11555224|imex:IM-24995-4377	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000166925(gene)|ensembl:ENST00000300181(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006970"(response to osmotic stress)|interpro:IPR000580(TSC-22 / Dip / Bun)|interpro:IPR042553|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|refseq:NP_112197.1|refseq:NP_001289972.1	interpro:IPR036249|refseq:NP_010006.1|sgd:S000000679|interpro:IPR017937|interpro:IPR013766(Thioredoxin domain)|rcsb pdb:2OE0|rcsb pdb:2OE1|rcsb pdb:2OE3|ensemblfungi:YCR083W(gene)|ensemblfungi:YCR083W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0015036"(disulfide oxidoreductase activity)|go:"GO:0034599"(cellular response to oxidative stress)|rcsb pdb:5YKW	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:eL12cHY76zEPOXzT1HFKPSckS8Y9606	rogid:g0xjGf9GvJRl8iv2qoT5tOs7jXI559292	intact-crc:5E853C1C03B4956F|rigid:YczFP5l/qUDh5ND1iOxBAW2Cp9w	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P46948	uniprotkb:Q9Y3Q8	intact:EBI-1788|uniprotkb:D6VUX7|ensemblfungi:YGR195W	intact:EBI-739485|uniprotkb:A8MWR6|ensembl:ENSP00000300181|uniprotkb:A4D2C3|uniprotkb:D6W5V9	psi-mi:rrp41_yeast(display_long)|uniprotkb:SKI6(gene name)|psi-mi:SKI6(display_short)|uniprotkb:YGR195W(locus name)|uniprotkb:G7587(orf name)|uniprotkb:ECM20(gene name synonym)|uniprotkb:Ribosomal RNA-processing protein 41(gene name synonym)|uniprotkb:Superkiller protein 6(gene name synonym)|uniprotkb:Extracellular mutant protein 20(gene name synonym)|uniprotkb:RRP41(gene name synonym)	psi-mi:t22d4_human(display_long)|uniprotkb:TSC22D4(gene name)|psi-mi:TSC22D4(display_short)|uniprotkb:TILZ2(gene name synonym)|uniprotkb:TSC22-related-inducible leucine zipper protein 2(gene name synonym)|uniprotkb:Tsc-22-like protein THG-1(gene name synonym)|uniprotkb:THG1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11555220|imex:IM-24995-4376	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003427|refseq:NP_011711.3|dip:DIP-2083N|mint:P46948|ensemblfungi:YGR195W(gene)|ensemblfungi:YGR195W_mRNA(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034473"(U1 snRNA 3'-end processing)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0034476"(U5 snRNA 3'-end processing)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071039"(nuclear polyadenylation-dependent CUT catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345|rcsb pdb:2WP8|rcsb pdb:4IFD|rcsb pdb:4OO1|rcsb pdb:5C0W|rcsb pdb:5C0X|rcsb pdb:5G06|rcsb pdb:5JEA|rcsb pdb:5K36|rcsb pdb:5OKZ|rcsb pdb:5VZJ|rcsb pdb:6FSZ|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-429958|reactome:R-SCE-450385|reactome:R-SCE-450513|reactome:R-SCE-6791226	ensembl:ENSG00000166925(gene)|ensembl:ENST00000300181(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006970"(response to osmotic stress)|interpro:IPR000580(TSC-22 / Dip / Bun)|interpro:IPR042553|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|refseq:NP_112197.1|refseq:NP_001289972.1	-	crc64:C80EFFB528A43044	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:I7vEo0EUB1jZO+3v12H0LwVbgmo559292	rogid:eL12cHY76zEPOXzT1HFKPSckS8Y9606	intact-crc:B9DFB1321EC8DDD4|rigid:ZXtHWRBKdozAbydNT2AWOJTR0OE	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P40368	uniprotkb:Q9Y3C0	intact:EBI-12331|ensemblfungi:YJL061W|uniprotkb:D6VWC1	intact:EBI-712969|ensembl:ENSP00000240079|uniprotkb:Q53FF0|uniprotkb:Q6IAI4|uniprotkb:Q96QK0|uniprotkb:B2RC74	psi-mi:nup82_yeast(display_long)|uniprotkb:NUP82(gene name)|psi-mi:NUP82(display_short)|uniprotkb:YJL061W(locus name)|uniprotkb:J1135(orf name)|uniprotkb:HRB187(orf name)|uniprotkb:Nuclear pore protein NUP82(gene name synonym)	psi-mi:wasc3_human(display_long)|uniprotkb:WASHC3(gene name)|psi-mi:WASHC3(display_short)|uniprotkb:Coiled-coil domain-containing protein 53(gene name synonym)|uniprotkb:AD-016(orf name)|uniprotkb:CCDC53(orf name)|uniprotkb:CGI-116(orf name)|uniprotkb:x0009(orf name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11555204|imex:IM-24995-4372	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012474.1|sgd:S000003597|ensemblfungi:YJL061W(gene)|ensemblfungi:YJL061W_mRNA(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0005634"(nucleus)|interpro:IPR037700|rcsb pdb:3PBP|rcsb pdb:3TKN|go:"GO:0005643"(nuclear pore)|go:"GO:0005829"(cytosol)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0044612"(nuclear pore linkers)|go:"GO:0044614"(nuclear pore cytoplasmic filaments)|mint:P40368|dip:DIP-913N	ensembl:ENSG00000120860(gene)|ensembl:ENST00000240079(transcript)|go:"GO:0005769"(early endosome)|go:"GO:0006887"(exocytosis)|go:"GO:0015031"(protein transport)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0071203"(WASH complex)|interpro:IPR019309|mint:Q9Y3C0|refseq:NP_057137.1	-	crc64:C379B5E111E26B50	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:g1+jqOMmde8phrNI9H7nFlXwjH0559292	rogid:jonEQJt0wEcrS2YEiKcmmIiZjCA9606	intact-crc:00E17A2914F5B483|rigid:+K6/4kcgYqa47kJX3VAfnTyqRmY	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P32502	uniprotkb:Q9Y3Q8	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	intact:EBI-739485|uniprotkb:A8MWR6|ensembl:ENSP00000300181|uniprotkb:A4D2C3|uniprotkb:D6W5V9	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:t22d4_human(display_long)|uniprotkb:TSC22D4(gene name)|psi-mi:TSC22D4(display_short)|uniprotkb:TILZ2(gene name synonym)|uniprotkb:TSC22-related-inducible leucine zipper protein 2(gene name synonym)|uniprotkb:Tsc-22-like protein THG-1(gene name synonym)|uniprotkb:THG1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11555212|imex:IM-24995-4374	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731	ensembl:ENSG00000166925(gene)|ensembl:ENST00000300181(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006970"(response to osmotic stress)|interpro:IPR000580(TSC-22 / Dip / Bun)|interpro:IPR042553|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|refseq:NP_112197.1|refseq:NP_001289972.1	-	crc64:A5409FAF1594854C	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	rogid:eL12cHY76zEPOXzT1HFKPSckS8Y9606	intact-crc:5952031FDA6899B0|rigid:Di+XqheOggbNvebETiEmKrLRyVg	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9Y3Q8	uniprotkb:P40455	intact:EBI-739485|uniprotkb:A8MWR6|ensembl:ENSP00000300181|uniprotkb:A4D2C3|uniprotkb:D6W5V9	intact:EBI-25274|uniprotkb:D6VVD5|ensemblfungi:YIL152W	psi-mi:t22d4_human(display_long)|uniprotkb:TSC22D4(gene name)|psi-mi:TSC22D4(display_short)|uniprotkb:TILZ2(gene name synonym)|uniprotkb:TSC22-related-inducible leucine zipper protein 2(gene name synonym)|uniprotkb:Tsc-22-like protein THG-1(gene name synonym)|uniprotkb:THG1(gene name synonym)	psi-mi:yip2_yeast(display_long)|uniprotkb:YIL152W(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11555208|imex:IM-24995-4373	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000166925(gene)|ensembl:ENST00000300181(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006970"(response to osmotic stress)|interpro:IPR000580(TSC-22 / Dip / Bun)|interpro:IPR042553|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|refseq:NP_112197.1|refseq:NP_001289972.1	sgd:S000001414|refseq:NP_012114.1|mint:P40455|dip:DIP-2047N|ensemblfungi:YIL152W(gene)|ensemblfungi:YIL152W_mRNA(transcript)	-	-	crc64:07550E3F491F53A8	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:eL12cHY76zEPOXzT1HFKPSckS8Y9606	rogid:t5hCm1ck6kpFUxpEd8CsyLrHbEw559292	intact-crc:A408617DEAFD5091|rigid:PGN/CnxnWOmURFFkj+OFUHbLKt4	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P28004	uniprotkb:Q9Y3Q8	intact:EBI-20640|uniprotkb:D6VPI6|ensemblfungi:YAL032C	intact:EBI-739485|uniprotkb:A8MWR6|ensembl:ENSP00000300181|uniprotkb:A4D2C3|uniprotkb:D6W5V9	psi-mi:prp45_yeast(display_long)|uniprotkb:YAL032C(locus name)|uniprotkb:PRP45(gene name)|psi-mi:PRP45(display_short)|uniprotkb:FUN20(gene name synonym)	psi-mi:t22d4_human(display_long)|uniprotkb:TSC22D4(gene name)|psi-mi:TSC22D4(display_short)|uniprotkb:TILZ2(gene name synonym)|uniprotkb:TSC22-related-inducible leucine zipper protein 2(gene name synonym)|uniprotkb:Tsc-22-like protein THG-1(gene name synonym)|uniprotkb:THG1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11555216|imex:IM-24995-4375	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009370.1|sgd:S000000030|ensemblfungi:YAL032C(gene)|ensemblfungi:YAL032C_mRNA(transcript)|go:"GO:0000350"(generation of catalytic spliceosome for second transesterification step)|go:"GO:0005634"(nucleus)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|interpro:IPR004015(SKIP/SNW)|interpro:IPR017862|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|dip:DIP-2774N|mint:P28004	ensembl:ENSG00000166925(gene)|ensembl:ENST00000300181(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006970"(response to osmotic stress)|interpro:IPR000580(TSC-22 / Dip / Bun)|interpro:IPR042553|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|refseq:NP_112197.1|refseq:NP_001289972.1	-	crc64:FE5A724186D7FE84	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:qoHF1UsO3k+JOTOfigSuy2P84/k559292	rogid:eL12cHY76zEPOXzT1HFKPSckS8Y9606	intact-crc:D53BC243FA2178DB|rigid:riVze4uPf7Sha0q+RYw99zeY8eI	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P53933	uniprotkb:Q9Y5X1	intact:EBI-28798|uniprotkb:D6W186|ensemblfungi:YNL094W	intact:EBI-77848|ensembl:ENSP00000376024|ensembl:ENSP00000506326|uniprotkb:Q9BSI7|uniprotkb:Q9BVM1|uniprotkb:Q9UJH6|uniprotkb:Q9UP20	psi-mi:app1_yeast(display_long)|uniprotkb:APP1(gene name)|psi-mi:APP1(display_short)|uniprotkb:Actin patch protein 1(gene name synonym)|uniprotkb:N2219(orf name)|uniprotkb:YNL094W(locus name)	psi-mi:snx9_human(display_long)|uniprotkb:SNX9(gene name)|psi-mi:SNX9(display_short)|uniprotkb:SH3PX1(gene name synonym)|uniprotkb:SH3PXD3A(gene name synonym)|uniprotkb:SH3 and PX domain-containing protein 1(gene name synonym)|uniprotkb:SH3 and PX domain-containing protein 3A(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11555248|imex:IM-24995-4383	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014305.1|sgd:S000005038|dip:DIP-2006N|mint:P53933|ensemblfungi:YNL094W(gene)|ensemblfungi:YNL094W_mRNA(transcript)|go:"GO:0008195"(phosphatidate phosphatase activity)|go:"GO:0030479"(actin cortical patch)|go:"GO:0044255"(cellular lipid metabolic process)|interpro:IPR017210(Uncharacterised conserved protein UCP037464, actin patch protein 1)|interpro:IPR019236	ensembl:ENSG00000130340(gene)|ensembl:ENST00000392185(transcript)|ensembl:ENST00000679814(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0001726"(ruffle)|go:"GO:0005545"(1-phosphatidylinositol binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006897"(endocytosis)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0016197"(endosomal transport)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032437"(cuticular plate)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0036089"(cleavage furrow formation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0051044"(positive regulation of membrane protein ectodomain proteolysis)|go:"GO:0060988"(lipid tube assembly)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071933"(Arp2/3 complex binding)|go:"GO:0097320"(plasma membrane tubulation)|interpro:IPR001452(Src homology-3)|interpro:IPR001683(Phox-like)|interpro:IPR014536(Sorting nexin, Snx9 type)|interpro:IPR019497|interpro:IPR027267|interpro:IPR028644|interpro:IPR035558|interpro:IPR036028|interpro:IPR036871|interpro:IPR037425|interpro:IPR037426|mint:Q9Y5X1|rcsb pdb:2RAI|rcsb pdb:2RAJ|rcsb pdb:2RAK|rcsb pdb:3DYT|rcsb pdb:3DYU|rcsb pdb:3LGE|reactome:R-HSA-432722|reactome:R-HSA-8856828|refseq:NP_057308.1|dip:DIP-30997N	-	crc64:B85C525548BA34BC	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:4ORrWVN2DOL+59LI2qWcKYYVfcE559292	rogid:qtqmMew2psrK6OJPAOWQGTVmNJA9606	intact-crc:86E2FCD231270FC9|rigid:heE4QMrICB90mjOoLbcWatLpn+8	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q02256	uniprotkb:Q9Y5P8-2	intact:EBI-14322|uniprotkb:D6VVV7|ensemblfungi:YIR026C	intact:EBI-11534240	psi-mi:pvh1_yeast(display_long)|uniprotkb:YIR026C(locus name)|uniprotkb:YVH1(gene name)|psi-mi:YVH1(display_short)	psi-mi:q9y5p8-2(display_long)|uniprotkb:PP2A subunit B isoform PR48(gene name synonym)|uniprotkb:PPP2R3L(gene name synonym)|uniprotkb:Protein phosphatase 2A 48 kDa regulatory subunit(gene name synonym)|uniprotkb:PPP2R3B(gene name)|psi-mi:PPP2R3B(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11555244|imex:IM-24995-4382	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YIR026C_mRNA(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|ensemblfungi:YIR026C(gene)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0008138"(protein tyrosine/serine/threonine phosphatase activity)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0030476"(ascospore wall assembly)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:1990275"(preribosome binding)|go:"GO:2000786"(positive regulation of autophagosome assembly)|interpro:IPR000340(Protein-tyrosine phosphatase, dual specificity)|interpro:IPR000387(Protein-tyrosine phosphatase)|sgd:S000001465|interpro:IPR020422|interpro:IPR029021|rcsb pdb:6N8M|interpro:IPR016278(Tyrosine protein phosphatase, dual specificity, 12)|rcsb pdb:6N8N|rcsb pdb:6N8O|rcsb pdb:6RZZ|rcsb pdb:6S05|refseq:NP_012292.3|mint:Q02256|dip:DIP-5192N	intact:EBI-2479826(isoform-parent)	-	crc64:9E75C7CC14353B43	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:9C9+S3aubsVjSLE5Kklpws+PA0A559292	rogid:u/vhz15um2LQ5BCN/pXjf+NVCTc9606	intact-crc:01262D62CEDB4262|rigid:VWGXq5x4MxFS/EKpecUkXmORX84	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q03020	uniprotkb:Q9Y3Q8	intact:EBI-29901|uniprotkb:D6W3N2|ensemblfungi:YPL135W	intact:EBI-739485|uniprotkb:A8MWR6|ensembl:ENSP00000300181|uniprotkb:A4D2C3|uniprotkb:D6W5V9	psi-mi:isu1_yeast(display_long)|uniprotkb:YPL135W(locus name)|uniprotkb:Iron sulfur cluster scaffold protein 1(gene name synonym)|uniprotkb:ISU1(gene name)|psi-mi:ISU1(display_short)|uniprotkb:NUA1(gene name synonym)	psi-mi:t22d4_human(display_long)|uniprotkb:TSC22D4(gene name)|psi-mi:TSC22D4(display_short)|uniprotkb:TILZ2(gene name synonym)|uniprotkb:TSC22-related-inducible leucine zipper protein 2(gene name synonym)|uniprotkb:Tsc-22-like protein THG-1(gene name synonym)|uniprotkb:THG1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11555228|imex:IM-24995-4378	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015190.1|sgd:S000006056|dip:DIP-6556N|mint:Q03020|ensemblfungi:YPL135W(gene)|ensemblfungi:YPL135W_mRNA(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005506"(iron ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR002871(NIF system FeS cluster assembly, NifU, N-terminal)|interpro:IPR011339(ISC system FeS cluster assembly, IscU scaffold)|rcsb pdb:5T0V|rcsb pdb:5TRE|reactome:R-SCE-1362409	ensembl:ENSG00000166925(gene)|ensembl:ENST00000300181(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006970"(response to osmotic stress)|interpro:IPR000580(TSC-22 / Dip / Bun)|interpro:IPR042553|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|refseq:NP_112197.1|refseq:NP_001289972.1	-	crc64:E240845A27D2E9EE	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:zpPseOgZoK3cF+mCetzw05ct9Kc559292	rogid:eL12cHY76zEPOXzT1HFKPSckS8Y9606	intact-crc:A3FA653800F1BE95|rigid:7/fk/v7+VK0rnscXpMwupZD/a2Y	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P15732	uniprotkb:Q9Y4K3	intact:EBI-2097669|uniprotkb:D6VS45|ensemblfungi:YDR059C	intact:EBI-359276|uniprotkb:Q8NEH5|uniprotkb:A6NKI7|uniprotkb:A8KAB3|ensembl:ENSP00000337853|ensembl:ENSP00000433623|uniprotkb:D3DR16	psi-mi:ubc5_yeast(display_long)|uniprotkb:UBC5(gene name)|psi-mi:UBC5(display_short)|uniprotkb:Ubiquitin-protein ligase(gene name synonym)|uniprotkb:Ubiquitin carrier protein(gene name synonym)|uniprotkb:YD9609.13C(orf name)|uniprotkb:D4234(orf name)|uniprotkb:YDR059C(locus name)|uniprotkb:E2 ubiquitin-conjugating enzyme 5(gene name synonym)	psi-mi:traf6_human(display_long)|uniprotkb:TRAF6(gene name)|psi-mi:TRAF6(display_short)|uniprotkb:RNF85(gene name synonym)|uniprotkb:Interleukin-1 signal transducer(gene name synonym)|uniprotkb:RING finger protein 85(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase TRAF6(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRAF6(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11555236|imex:IM-24995-4380	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010344.1|sgd:S000002466|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR023313|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|mint:P15732|ensemblfungi:YDR059C(gene)|ensemblfungi:YDR059C_mRNA(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034605"(cellular response to heat)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070628"(proteasome binding)|reactome:R-SCE-8866652|reactome:R-SCE-8866654|reactome:R-SCE-9033241|reactome:R-SCE-983168	refseq:NP_004611.1|refseq:NP_665802.1|ensembl:ENSG00000175104(gene)|ensembl:ENST00000348124(transcript)|ensembl:ENST00000526995(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001503"(ossification)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001843"(neural tube closure)|go:"GO:0002223"(stimulatory C-type lectin receptor signaling pathway)|go:"GO:0002637"(regulation of immunoglobulin production)|go:"GO:0002726"(positive regulation of T cell cytokine production)|go:"GO:0002753"(cytoplasmic pattern recognition receptor signaling pathway)|go:"GO:0002755"(MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007254"(JNK cascade)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030316"(osteoclast differentiation)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031666"(positive regulation of lipopolysaccharide-mediated signaling pathway)|go:"GO:0031996"(thioesterase binding)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035631"(CD40 receptor complex)|go:"GO:0038095"(Fc-epsilon receptor signaling pathway)|go:"GO:0042088"(T-helper 1 type immune response)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043011"(myeloid dendritic cell differentiation)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0045453"(bone resorption)|go:"GO:0045672"(positive regulation of osteoclast differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048468"(cell development)|go:"GO:0032813"(tumor necrosis factor receptor superfamily binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051865"(protein autoubiquitination)|interpro:IPR012227(TNF receptor-associated factor TRAF)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR027139|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070498"(interleukin-1-mediated signaling pathway)|interpro:IPR037309|interpro:IPR041310|interpro:IPR043211|mint:Q9Y4K3|rcsb pdb:1LB4|rcsb pdb:1LB5|go:"GO:0070534"(protein K63-linked ubiquitination)|rcsb pdb:1LB6|rcsb pdb:2ECI|rcsb pdb:2JMD|rcsb pdb:3HCS|rcsb pdb:3HCT|rcsb pdb:3HCU|rcsb pdb:4Z8M|rcsb pdb:5ZUJ|rcsb pdb:6A33|go:"GO:0070555"(response to interleukin-1)|rcsb pdb:7L3L|reactome:R-HSA-1257604|reactome:R-HSA-166058|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-205043|go:"GO:0071222"(cellular response to lipopolysaccharide)|reactome:R-HSA-209543|reactome:R-HSA-209560|reactome:R-HSA-2871837|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0097400"(interleukin-17-mediated signaling pathway)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1904996"(positive regulation of leukocyte adhesion to vascular endothelial cell)|go:"GO:2000679"(positive regulation of transcription regulatory region DNA binding)|interpro:IPR001293(Zinc finger, TRAF-type)|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-5607764|reactome:R-HSA-5689880|reactome:R-HSA-5689896|reactome:R-HSA-6811558|reactome:R-HSA-9014325|reactome:R-HSA-9020702|reactome:R-HSA-933541|reactome:R-HSA-933542|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-937042|reactome:R-HSA-937072|reactome:R-HSA-9645460|reactome:R-HSA-975110|reactome:R-HSA-975138|reactome:R-HSA-975144|reactome:R-HSA-975155|reactome:R-HSA-975163|reactome:R-HSA-975871|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|dip:DIP-27515N	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:lhkS9orGIZV1O+L0mEfzlpRvgtk559292	rogid:m0TTXwlrtXnnjXWbg0MsEULlq0I9606	intact-crc:0EE6BF1DD8C1A1AA|rigid:WyHHVlaKokHfqjsp56sg2/L1Sg8	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9Y3Q8	uniprotkb:P40454	intact:EBI-739485|uniprotkb:A8MWR6|ensembl:ENSP00000300181|uniprotkb:A4D2C3|uniprotkb:D6W5V9	intact:EBI-25278|uniprotkb:D6VVD4|ensemblfungi:YIL153W	psi-mi:t22d4_human(display_long)|uniprotkb:TSC22D4(gene name)|psi-mi:TSC22D4(display_short)|uniprotkb:TILZ2(gene name synonym)|uniprotkb:TSC22-related-inducible leucine zipper protein 2(gene name synonym)|uniprotkb:Tsc-22-like protein THG-1(gene name synonym)|uniprotkb:THG1(gene name synonym)	psi-mi:ptpa1_yeast(display_long)|uniprotkb:YIL153W(locus name)|uniprotkb:RRD1(gene name)|psi-mi:RRD1(display_short)|uniprotkb:NCS1(gene name synonym)|uniprotkb:YPA1(gene name synonym)|uniprotkb:Peptidyl-prolyl cis-trans isomerase PTPA-1(gene name synonym)|uniprotkb:Phosphotyrosyl phosphatase activator 1(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11555232|imex:IM-24995-4379	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000166925(gene)|ensembl:ENST00000300181(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006970"(response to osmotic stress)|interpro:IPR000580(TSC-22 / Dip / Bun)|interpro:IPR042553|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|refseq:NP_112197.1|refseq:NP_001289972.1	refseq:NP_012113.1|sgd:S000001415|mint:P40454|dip:DIP-5663N|ensemblfungi:YIL153W(gene)|ensemblfungi:YIL153W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006914"(autophagy)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008160"(protein tyrosine phosphatase activator activity)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0043618"(regulation of transcription from RNA polymerase II promoter in response to stress)|interpro:IPR004327(Phosphotyrosyl phosphatase activator, PTPA)|interpro:IPR037218|interpro:IPR043170|rcsb pdb:2IXO|rcsb pdb:2IXP	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:eL12cHY76zEPOXzT1HFKPSckS8Y9606	rogid:It2q8WlpmvLEZ1fqpRF5Fypw9Q4559292	intact-crc:592260592B4EA6F4|rigid:Z3ZOSQgaqcMkkGs4LrBuRiUQYSc	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P13130	uniprotkb:Q9Y5P4-2	intact:EBI-11523294|uniprotkb:D3DL88|ensemblfungi:YHR139C	intact:EBI-11156432|ensembl:ENSP00000493563|ensembl:ENSP00000495446|ensembl:ENSP00000496243	psi-mi:ss100_yeast(display_long)|uniprotkb:SPS100(gene name)|psi-mi:SPS100(display_short)|uniprotkb:YHR139C(locus name)	psi-mi:q9y5p4-2(display_long)|uniprotkb:Goodpasture antigen-binding protein(gene name synonym)|uniprotkb:STARD11(gene name synonym)|uniprotkb:START domain-containing protein 11(gene name synonym)|uniprotkb:StAR-related lipid transfer protein 11(gene name synonym)|uniprotkb:CERT(isoform synonym)|uniprotkb:Delta26(isoform synonym)|uniprotkb:GPBPD26(isoform synonym)|uniprotkb:CERT(gene name synonym)|uniprotkb:COL4A3BP(gene name synonym)|uniprotkb:CERT1(gene name)|psi-mi:CERT1(display_short)|uniprotkb:Collagen type IV alpha-3-binding protein(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11555240|imex:IM-24995-4381	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR006034(Asparaginase/glutaminase)|refseq:NP_012007.1|sgd:S000001181|ensemblfungi:YHR139C(gene)|ensemblfungi:YHR139C_mRNA(transcript)|go:"GO:0030476"(ascospore wall assembly)|interpro:IPR036152	ensembl:ENSG00000113163(gene)|ensembl:ENST00000644445(transcript)|ensembl:ENST00000645483(transcript)|ensembl:ENST00000646511(transcript)|intact:EBI-739994(isoform-parent)|uniprotkb:Q9Y5P4-2(isoform-parent)	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/03/16	rogid:ThKMilyLHPEAiJu+3ty4DXcUEE4559292	rogid:UXQeqtW4rknHeYKQlqBZ9HMX8Qs9606	intact-crc:3079BE29C31E4EE9|rigid:VsTEV5Bu7ezKNSFK0ZMGd3Tp0yo	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9Y6D9	uniprotkb:P53933	intact:EBI-742610|uniprotkb:B3KR41|uniprotkb:Q9UNH0|uniprotkb:Q13312|uniprotkb:Q75MI0|uniprotkb:Q86UM4|ensembl:ENSP00000265854|ensembl:ENSP00000382562|ensembl:ENSP00000385334	intact:EBI-28798|uniprotkb:D6W186|ensemblfungi:YNL094W	psi-mi:md1l1_human(display_long)|uniprotkb:Mitotic arrest deficient 1-like protein 1(gene name synonym)|uniprotkb:Mitotic checkpoint MAD1 protein homolog(gene name synonym)|uniprotkb:Tax-binding protein 181(gene name synonym)|uniprotkb:MAD1L1(gene name)|psi-mi:MAD1L1(display_short)|uniprotkb:MAD1(gene name synonym)|uniprotkb:TXBP181(gene name synonym)	psi-mi:app1_yeast(display_long)|uniprotkb:APP1(gene name)|psi-mi:APP1(display_short)|uniprotkb:Actin patch protein 1(gene name synonym)|uniprotkb:N2219(orf name)|uniprotkb:YNL094W(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11555272|imex:IM-24995-4389	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001013858.1|refseq:NP_001013859.1|refseq:NP_003541.2|refseq:NP_001291452.1|refseq:NP_001291453.1|ensembl:ENSG00000002822(gene)|ensembl:ENST00000265854(transcript)|go:"GO:0090235"(regulation of metaphase plate congression)|go:"GO:1902426"(deactivation of mitotic spindle assembly checkpoint)|interpro:IPR008672(Mitotic checkpoint)|mint:Q9Y6D9|rcsb pdb:1GO4|rcsb pdb:4DZO|rcsb pdb:7B1F|rcsb pdb:7B1H|rcsb pdb:7B1J|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|ensembl:ENST00000399654(transcript)|ensembl:ENST00000406869(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043515"(kinetochore binding)|go:"GO:0044615"(nuclear pore nuclear basket)|go:"GO:0048538"(thymus development)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0072686"(mitotic spindle)|refseq:XP_005249934.1|dip:DIP-29654N	refseq:NP_014305.1|sgd:S000005038|dip:DIP-2006N|mint:P53933|ensemblfungi:YNL094W(gene)|ensemblfungi:YNL094W_mRNA(transcript)|go:"GO:0008195"(phosphatidate phosphatase activity)|go:"GO:0030479"(actin cortical patch)|go:"GO:0044255"(cellular lipid metabolic process)|interpro:IPR017210(Uncharacterised conserved protein UCP037464, actin patch protein 1)|interpro:IPR019236	-	-	crc64:B85C525548BA34BC	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:9CcqpZlN0IgqC939rIo7vNgOvLQ9606	rogid:4ORrWVN2DOL+59LI2qWcKYYVfcE559292	intact-crc:76929F0ED7C15530|rigid:DNKK0rxktXI+kd4CBEvrsnfZ2CA	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9Y6D9	uniprotkb:P32502	intact:EBI-742610|uniprotkb:B3KR41|uniprotkb:Q9UNH0|uniprotkb:Q13312|uniprotkb:Q75MI0|uniprotkb:Q86UM4|ensembl:ENSP00000265854|ensembl:ENSP00000382562|ensembl:ENSP00000385334	intact:EBI-6260|uniprotkb:D6VYT7|ensemblfungi:YLR291C	psi-mi:md1l1_human(display_long)|uniprotkb:Mitotic arrest deficient 1-like protein 1(gene name synonym)|uniprotkb:Mitotic checkpoint MAD1 protein homolog(gene name synonym)|uniprotkb:Tax-binding protein 181(gene name synonym)|uniprotkb:MAD1L1(gene name)|psi-mi:MAD1L1(display_short)|uniprotkb:MAD1(gene name synonym)|uniprotkb:TXBP181(gene name synonym)	psi-mi:ei2bb_yeast(display_long)|uniprotkb:GCD7(gene name)|psi-mi:GCD7(display_short)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:GCD complex subunit GCD7(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor subunit GCD7(gene name synonym)|uniprotkb:TIF222(gene name synonym)|uniprotkb:L8003.17(orf name)|uniprotkb:YLR291C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11555268|imex:IM-24995-4388	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001013858.1|refseq:NP_001013859.1|refseq:NP_003541.2|refseq:NP_001291452.1|refseq:NP_001291453.1|ensembl:ENSG00000002822(gene)|ensembl:ENST00000265854(transcript)|go:"GO:0090235"(regulation of metaphase plate congression)|go:"GO:1902426"(deactivation of mitotic spindle assembly checkpoint)|interpro:IPR008672(Mitotic checkpoint)|mint:Q9Y6D9|rcsb pdb:1GO4|rcsb pdb:4DZO|rcsb pdb:7B1F|rcsb pdb:7B1H|rcsb pdb:7B1J|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|ensembl:ENST00000399654(transcript)|ensembl:ENST00000406869(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043515"(kinetochore binding)|go:"GO:0044615"(nuclear pore nuclear basket)|go:"GO:0048538"(thymus development)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0072686"(mitotic spindle)|refseq:XP_005249934.1|dip:DIP-29654N	refseq:NP_013394.1|sgd:S000004282|dip:DIP-1185N|mint:P32502|ensemblfungi:YLR291C(gene)|ensemblfungi:YLR291C_mRNA(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6I3M|rcsb pdb:6I7T|rcsb pdb:6QG0|rcsb pdb:6QG1|rcsb pdb:6QG2|rcsb pdb:6QG3|rcsb pdb:6QG5|rcsb pdb:6QG6|reactome:R-SCE-72731	-	-	crc64:A5409FAF1594854C	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:9CcqpZlN0IgqC939rIo7vNgOvLQ9606	rogid:q1S3/Y7SQ6GxEkTz0kycc3b2B8I559292	intact-crc:52AFCF26BF2F4A34|rigid:i1ztDpU8PgAzP0pVDv/71CBfv5k	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P32571	uniprotkb:Q9Y6D9	intact:EBI-19840|uniprotkb:D6VS55|ensemblfungi:YDR069C	intact:EBI-742610|uniprotkb:B3KR41|uniprotkb:Q9UNH0|uniprotkb:Q13312|uniprotkb:Q75MI0|uniprotkb:Q86UM4|ensembl:ENSP00000265854|ensembl:ENSP00000382562|ensembl:ENSP00000385334	psi-mi:ubp4_yeast(display_long)|uniprotkb:DOA4(gene name)|psi-mi:DOA4(display_short)|uniprotkb:MUT4(gene name synonym)|uniprotkb:SSV7(gene name synonym)|uniprotkb:YDR069C(locus name)|uniprotkb:YD9609.23C(orf name)|uniprotkb:YD8554.02C(orf name)|uniprotkb:D4270(orf name)|uniprotkb:NPI2(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 4(gene name synonym)|uniprotkb:Deubiquitinating enzyme 4(gene name synonym)|uniprotkb:Vacuole biogenesis protein SSV7(gene name synonym)|uniprotkb:Ubiquitin thioesterase 4(gene name synonym)|uniprotkb:DOS1(gene name synonym)|uniprotkb:UBP4(gene name synonym)	psi-mi:md1l1_human(display_long)|uniprotkb:Mitotic arrest deficient 1-like protein 1(gene name synonym)|uniprotkb:Mitotic checkpoint MAD1 protein homolog(gene name synonym)|uniprotkb:Tax-binding protein 181(gene name synonym)|uniprotkb:MAD1L1(gene name)|psi-mi:MAD1L1(display_short)|uniprotkb:MAD1(gene name synonym)|uniprotkb:TXBP181(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11555252|imex:IM-24995-4384	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002476|ensemblfungi:YDR069C(gene)|ensemblfungi:YDR069C_mRNA(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005739"(mitochondrion)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0010992"(ubiquitin recycling)|go:"GO:0010995"(free ubiquitin chain depolymerization)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0031902"(late endosome membrane)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0070676"(intralumenal vesicle formation)|go:"GO:1904669"(ATP export)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR001763(Rhodanese-like)|interpro:IPR018200|interpro:IPR028889|interpro:IPR036873|interpro:IPR038765|refseq:NP_010354.3|dip:DIP-5298N|mint:P32571	refseq:NP_001013858.1|refseq:NP_001013859.1|refseq:NP_003541.2|refseq:NP_001291452.1|refseq:NP_001291453.1|ensembl:ENSG00000002822(gene)|ensembl:ENST00000265854(transcript)|go:"GO:0090235"(regulation of metaphase plate congression)|go:"GO:1902426"(deactivation of mitotic spindle assembly checkpoint)|interpro:IPR008672(Mitotic checkpoint)|mint:Q9Y6D9|rcsb pdb:1GO4|rcsb pdb:4DZO|rcsb pdb:7B1F|rcsb pdb:7B1H|rcsb pdb:7B1J|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|ensembl:ENST00000399654(transcript)|ensembl:ENST00000406869(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043515"(kinetochore binding)|go:"GO:0044615"(nuclear pore nuclear basket)|go:"GO:0048538"(thymus development)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0072686"(mitotic spindle)|refseq:XP_005249934.1|dip:DIP-29654N	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:UTBSWmpygyxo1ygxp/sQ8wgqnMo559292	rogid:9CcqpZlN0IgqC939rIo7vNgOvLQ9606	intact-crc:A9ADF2A709A19953|rigid:SJ0gDSH+tfkGAInWADUpSnggA8Y	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9Y6D9	uniprotkb:P28004	intact:EBI-742610|uniprotkb:B3KR41|uniprotkb:Q9UNH0|uniprotkb:Q13312|uniprotkb:Q75MI0|uniprotkb:Q86UM4|ensembl:ENSP00000265854|ensembl:ENSP00000382562|ensembl:ENSP00000385334	intact:EBI-20640|uniprotkb:D6VPI6|ensemblfungi:YAL032C	psi-mi:md1l1_human(display_long)|uniprotkb:Mitotic arrest deficient 1-like protein 1(gene name synonym)|uniprotkb:Mitotic checkpoint MAD1 protein homolog(gene name synonym)|uniprotkb:Tax-binding protein 181(gene name synonym)|uniprotkb:MAD1L1(gene name)|psi-mi:MAD1L1(display_short)|uniprotkb:MAD1(gene name synonym)|uniprotkb:TXBP181(gene name synonym)	psi-mi:prp45_yeast(display_long)|uniprotkb:YAL032C(locus name)|uniprotkb:PRP45(gene name)|psi-mi:PRP45(display_short)|uniprotkb:FUN20(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11555260|imex:IM-24995-4386	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001013858.1|refseq:NP_001013859.1|refseq:NP_003541.2|refseq:NP_001291452.1|refseq:NP_001291453.1|ensembl:ENSG00000002822(gene)|ensembl:ENST00000265854(transcript)|go:"GO:0090235"(regulation of metaphase plate congression)|go:"GO:1902426"(deactivation of mitotic spindle assembly checkpoint)|interpro:IPR008672(Mitotic checkpoint)|mint:Q9Y6D9|rcsb pdb:1GO4|rcsb pdb:4DZO|rcsb pdb:7B1F|rcsb pdb:7B1H|rcsb pdb:7B1J|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|ensembl:ENST00000399654(transcript)|ensembl:ENST00000406869(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043515"(kinetochore binding)|go:"GO:0044615"(nuclear pore nuclear basket)|go:"GO:0048538"(thymus development)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0072686"(mitotic spindle)|refseq:XP_005249934.1|dip:DIP-29654N	refseq:NP_009370.1|sgd:S000000030|ensemblfungi:YAL032C(gene)|ensemblfungi:YAL032C_mRNA(transcript)|go:"GO:0000350"(generation of catalytic spliceosome for second transesterification step)|go:"GO:0005634"(nucleus)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|interpro:IPR004015(SKIP/SNW)|interpro:IPR017862|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|dip:DIP-2774N|mint:P28004	-	-	crc64:FE5A724186D7FE84	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:9CcqpZlN0IgqC939rIo7vNgOvLQ9606	rogid:qoHF1UsO3k+JOTOfigSuy2P84/k559292	intact-crc:D2E9E098BB0E4047|rigid:kbuda1h/jrILQ/THd5wtekEKM/4	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P39976	uniprotkb:Q9Y6D9	intact:EBI-5933|uniprotkb:D3DLI0|ensemblfungi:YEL071W	intact:EBI-742610|uniprotkb:B3KR41|uniprotkb:Q9UNH0|uniprotkb:Q13312|uniprotkb:Q75MI0|uniprotkb:Q86UM4|ensembl:ENSP00000265854|ensembl:ENSP00000382562|ensembl:ENSP00000385334	psi-mi:dld3_yeast(display_long)|uniprotkb:YEL071W(locus name)|uniprotkb:DLD3(gene name)|psi-mi:DLD3(display_short)|uniprotkb:D-lactate ferricytochrome C oxidoreductase(gene name synonym)|uniprotkb:"(R)-2-hydroxyglutarate--pyruvate transhydrogenase"(gene name synonym)|uniprotkb:D-lactate dehydrogenase [cytochrome] 3(gene name synonym)	psi-mi:md1l1_human(display_long)|uniprotkb:Mitotic arrest deficient 1-like protein 1(gene name synonym)|uniprotkb:Mitotic checkpoint MAD1 protein homolog(gene name synonym)|uniprotkb:Tax-binding protein 181(gene name synonym)|uniprotkb:MAD1L1(gene name)|psi-mi:MAD1L1(display_short)|uniprotkb:MAD1(gene name synonym)|uniprotkb:TXBP181(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11555256|imex:IM-24995-4385	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010843.1|sgd:S000000797|dip:DIP-6418N|mint:P39976|ensemblfungi:YEL071W(gene)|ensemblfungi:YEL071W_mRNA(transcript)|go:"GO:0004458"("D-lactate dehydrogenase (cytochrome) activity")|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0019249"(lactate biosynthetic process)|go:"GO:0030447"(filamentous growth)|go:"GO:0071949"(FAD binding)|go:"GO:0099615"("(D)-2-hydroxyglutarate-pyruvate transhydrogenase activity")|interpro:IPR004113(FAD-linked oxidase, C-terminal)|interpro:IPR006094(FAD linked oxidase, N-terminal)|interpro:IPR016164(FAD-linked oxidase-like, C-terminal)|interpro:IPR016166(FAD-binding, type 2)|interpro:IPR016167(FAD-binding, type 2, subdomain 1)|interpro:IPR016169(CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2)|interpro:IPR016171(Vanillyl-alcohol oxidase, C-terminal subdomain 2)|interpro:IPR036318	refseq:NP_001013858.1|refseq:NP_001013859.1|refseq:NP_003541.2|refseq:NP_001291452.1|refseq:NP_001291453.1|ensembl:ENSG00000002822(gene)|ensembl:ENST00000265854(transcript)|go:"GO:0090235"(regulation of metaphase plate congression)|go:"GO:1902426"(deactivation of mitotic spindle assembly checkpoint)|interpro:IPR008672(Mitotic checkpoint)|mint:Q9Y6D9|rcsb pdb:1GO4|rcsb pdb:4DZO|rcsb pdb:7B1F|rcsb pdb:7B1H|rcsb pdb:7B1J|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|ensembl:ENST00000399654(transcript)|ensembl:ENST00000406869(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043515"(kinetochore binding)|go:"GO:0044615"(nuclear pore nuclear basket)|go:"GO:0048538"(thymus development)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0072686"(mitotic spindle)|refseq:XP_005249934.1|dip:DIP-29654N	-	crc64:4809F74EDF07F520	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:f0zrUtFfKHDu2gUN7thcyPp/Z50559292	rogid:9CcqpZlN0IgqC939rIo7vNgOvLQ9606	intact-crc:3D6CC8DF1B8B983E|rigid:T24bmbHLm6aNwasOX9GG0Wfbgy0	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9Y6D9	uniprotkb:Q03718	intact:EBI-742610|uniprotkb:B3KR41|uniprotkb:Q9UNH0|uniprotkb:Q13312|uniprotkb:Q75MI0|uniprotkb:Q86UM4|ensembl:ENSP00000265854|ensembl:ENSP00000382562|ensembl:ENSP00000385334	intact:EBI-27756|uniprotkb:D6VZF1|ensemblfungi:YML023C	psi-mi:md1l1_human(display_long)|uniprotkb:Mitotic arrest deficient 1-like protein 1(gene name synonym)|uniprotkb:Mitotic checkpoint MAD1 protein homolog(gene name synonym)|uniprotkb:Tax-binding protein 181(gene name synonym)|uniprotkb:MAD1L1(gene name)|psi-mi:MAD1L1(display_short)|uniprotkb:MAD1(gene name synonym)|uniprotkb:TXBP181(gene name synonym)	psi-mi:nse5_yeast(display_long)|uniprotkb:YML023C(locus name)|uniprotkb:NSE5(gene name)|psi-mi:NSE5(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11555264|imex:IM-24995-4387	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001013858.1|refseq:NP_001013859.1|refseq:NP_003541.2|refseq:NP_001291452.1|refseq:NP_001291453.1|ensembl:ENSG00000002822(gene)|ensembl:ENST00000265854(transcript)|go:"GO:0090235"(regulation of metaphase plate congression)|go:"GO:1902426"(deactivation of mitotic spindle assembly checkpoint)|interpro:IPR008672(Mitotic checkpoint)|mint:Q9Y6D9|rcsb pdb:1GO4|rcsb pdb:4DZO|rcsb pdb:7B1F|rcsb pdb:7B1H|rcsb pdb:7B1J|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|ensembl:ENST00000399654(transcript)|ensembl:ENST00000406869(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043515"(kinetochore binding)|go:"GO:0044615"(nuclear pore nuclear basket)|go:"GO:0048538"(thymus development)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0072686"(mitotic spindle)|refseq:XP_005249934.1|dip:DIP-29654N	refseq:NP_013689.1|sgd:S000004485|dip:DIP-4547N|ensemblfungi:YML023C(gene)|ensemblfungi:YML023C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0016925"(protein sumoylation)|go:"GO:0030915"(Smc5-Smc6 complex)|interpro:IPR014803(DNA repair protein Nse5)|rcsb pdb:7LTO	-	-	crc64:6680A04D91E537DD	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:9CcqpZlN0IgqC939rIo7vNgOvLQ9606	rogid:xDmbHW4E/uX4NGGcDCMXTnUDQGk559292	intact-crc:8C24C994B431E269|rigid:xPpbcd/v/e7dd9G01hJetUFUDS8	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9Y6N9-4	uniprotkb:P38781	intact:EBI-11523636|ensembl:ENSP00000436934	intact:EBI-24549|uniprotkb:D3DL05|ensemblfungi:YHR056C	psi-mi:q9y6n9-4(display_long)|uniprotkb:USH1C(gene name)|psi-mi:USH1C(display_short)|uniprotkb:AIE75(gene name synonym)|uniprotkb:Antigen NY-CO-38/NY-CO-37(gene name synonym)|uniprotkb:Autoimmune enteropathy-related antigen AIE-75(gene name synonym)|uniprotkb:Protein PDZ-73(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-3(gene name synonym)|uniprotkb:Usher syndrome type-1C protein(gene name synonym)	psi-mi:rsc30_yeast(display_long)|uniprotkb:RSC30(gene name)|psi-mi:RSC30(display_short)|uniprotkb:Remodel the structure of chromatin complex subunit 30(gene name synonym)|uniprotkb:YHR056C(locus name)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11555284|imex:IM-24995-4392	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000006611(gene)|ensembl:ENST00000527020(transcript)|intact:EBI-954308(isoform-parent)|uniprotkb:Q9Y6N9-4(isoform-parent)	refseq:NP_011923.2|sgd:S000001098|dip:DIP-4275N|ensemblfungi:YHR056C(gene)|ensemblfungi:YHR056C_mRNA(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006337"(nucleosome disassembly)|rcsb pdb:6KW4|rcsb pdb:6KW5|rcsb pdb:6V8O|rcsb pdb:6V92|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016586"(RSC-type complex)|interpro:IPR001138(Fungal transcriptional regulatory protein, N-terminal)|interpro:IPR036864|rcsb pdb:6K15|rcsb pdb:6KW3	-	isoform-comment:No experimental confirmation available.	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:lC4fbXfsFOZFtutcdQYHSWpgcJY9606	rogid:NzGOxIaNyDat2EcQdWPobugunh0559292	intact-crc:8C81818EBE24F50D|rigid:NGbrqKUhac/AX2xIvvMSab9r7RA	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9Y6K9	uniprotkb:Q04712	intact:EBI-81279|intact:EBI-356130|uniprotkb:Q7LBY6|uniprotkb:Q7Z7F1|ensembl:ENSP00000471166|ensembl:ENSP00000479662	intact:EBI-27790|uniprotkb:D6VZD2|ensemblfungi:YML043C	psi-mi:nemo_human(display_long)|uniprotkb:IKBKG(gene name)|psi-mi:IKBKG(display_short)|uniprotkb:FIP3(gene name synonym)|uniprotkb:NEMO(gene name synonym)|uniprotkb:NF-kappa-B essential modifier(gene name synonym)|uniprotkb:Inhibitor of nuclear factor kappa-B kinase subunit gamma(gene name synonym)|uniprotkb:IkB kinase-associated protein 1(gene name synonym)|uniprotkb:FIP-3(gene name synonym)	psi-mi:rrn11_yeast(display_long)|uniprotkb:YM9827.09C(orf name)|uniprotkb:YML043C(locus name)|uniprotkb:RRN11(gene name)|psi-mi:RRN11(display_short)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11555276|imex:IM-24995-4390	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001308325.1|refseq:NP_001308326.1|refseq:NP_001093326.2|refseq:NP_001093327.1|refseq:NP_001138727.1|refseq:NP_003630.1|dip:DIP-27528N|ensembl:ENSG00000269335(gene)|ensembl:ENST00000594239(transcript)|ensembl:ENST00000611071(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0008385"(IkappaB kinase complex)|go:"GO:0009615"(response to virus)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043276"(anoikis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050862"(positive regulation of T cell receptor signaling pathway)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051650"(establishment of vesicle localization)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1990450"(linear polyubiquitin binding)|go:"GO:1990459"(transferrin receptor binding)|interpro:IPR021063|interpro:IPR032419|interpro:IPR034735|mint:Q9Y6K9|rcsb pdb:2JVX|rcsb pdb:2JVY|rcsb pdb:3BRT|rcsb pdb:3BRV|rcsb pdb:3CL3|rcsb pdb:3FX0|rcsb pdb:4BWN|rcsb pdb:5AAY|rcsb pdb:5LDE|rcsb pdb:6MI3|rcsb pdb:6MI4|rcsb pdb:6YEK|reactome:R-HSA-1169091|reactome:R-HSA-1236974|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-1810476|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-4755510|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5602636|reactome:R-HSA-5603027|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5684264|reactome:R-HSA-5689880|reactome:R-HSA-5689896|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-933543|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-975144	refseq:NP_013669.1|sgd:S000004507|dip:DIP-4542N|mint:Q04712|ensemblfungi:YML043C(gene)|ensemblfungi:YML043C_mRNA(transcript)|go:"GO:0001164"(RNA polymerase I core promoter sequence-specific DNA binding)|go:"GO:0001181"(RNA polymerase I general transcription initiation factor activity)|go:"GO:0005730"(nucleolus)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0042790"(nucleolar large rRNA transcription by RNA polymerase I)|go:"GO:0070860"(RNA polymerase I core factor complex)|interpro:IPR007224(RNA polymerase I specific initiation factor)|interpro:IPR016850(Core factor complex, Rrn11 component)|rcsb pdb:5N5Y|rcsb pdb:5N5Z|rcsb pdb:5N60|rcsb pdb:5N61|rcsb pdb:5O7X|rcsb pdb:5OA1|rcsb pdb:5W5Y|rcsb pdb:5W64|rcsb pdb:5W65|rcsb pdb:5W66|rcsb pdb:6RQH|rcsb pdb:6RQL|rcsb pdb:6RRD|rcsb pdb:6RUI|rcsb pdb:6RUO|rcsb pdb:6RWE|rcsb pdb:6TPS	-	-	-	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/09	rogid:9OeZIMeJvNtDEMoiLaKwVEpxSSM9606	rogid:HeXVovHQGBfbg6FbSkFO9/T64hE559292	intact-crc:CD779060F40F917B|rigid:Yb0h9SnRLz93S+simkWtrCpcYQg	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P17967	uniprotkb:Q9Y6N9-4	intact:EBI-13012|uniprotkb:D6VQX3|ensemblfungi:YCL043C	intact:EBI-11523636|ensembl:ENSP00000436934	psi-mi:pdi_yeast(display_long)|uniprotkb:TRG1(gene name synonym)|uniprotkb:YCL313(orf name)|uniprotkb:PDI1(gene name)|psi-mi:PDI1(display_short)|uniprotkb:MFP1(gene name synonym)|uniprotkb:Thioredoxin-related glycoprotein 1(gene name synonym)|uniprotkb:YCL43C(orf name)|uniprotkb:YCL043C(locus name)	psi-mi:q9y6n9-4(display_long)|uniprotkb:USH1C(gene name)|psi-mi:USH1C(display_short)|uniprotkb:AIE75(gene name synonym)|uniprotkb:Antigen NY-CO-38/NY-CO-37(gene name synonym)|uniprotkb:Autoimmune enteropathy-related antigen AIE-75(gene name synonym)|uniprotkb:Protein PDZ-73(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-3(gene name synonym)|uniprotkb:Usher syndrome type-1C protein(gene name synonym)	psi-mi:"MI:1356"(validated two hybrid)	Zhong et al. (2015)	pubmed:27107014|imex:IM-24995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11555280|imex:IM-24995-4391	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009887.1|sgd:S000000548|mint:P17967|dip:DIP-4978N|ensemblfungi:YCL043C(gene)|ensemblfungi:YCL043C_mRNA(transcript)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006457"(protein folding)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0036508"(protein alpha-1,2-demannosylation)|go:"GO:0051082"(unfolded protein binding)|go:"GO:1904382"(mannose trimming involved in glycoprotein ERAD pathway)|interpro:IPR005792(Protein disulphide isomerase)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017937|interpro:IPR036249|rcsb pdb:2B5E|rcsb pdb:3BOA|reactome:R-SCE-901042	ensembl:ENSG00000006611(gene)|ensembl:ENST00000527020(transcript)|intact:EBI-954308(isoform-parent)|uniprotkb:Q9Y6N9-4(isoform-parent)	-	crc64:69CF3E05D7F74C94	isoform-comment:No experimental confirmation available.	figure legend:Table EV2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2015/12/14	2016/02/04	rogid:tyy52cf76yr9hl+9ggGGS4zDO/A559292	rogid:lC4fbXfsFOZFtutcdQYHSWpgcJY9606	intact-crc:C3439785A8151A16|rigid:O5OTQq4ev081rwavpiPaYwg+7MA	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)